[{"Gene":"ABCB6","Gene synonym":["EST45597","MTABC3","umat"],"Ensembl":"ENSG00000115657","Gene description":"ATP binding cassette subfamily B member 6 (Langereis blood group)","Uniprot":["Q9NP58"],"Chromosome":"2","Position":"219209772-219218994","Protein class":["Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":["Translocase"],"Disease involvement":["Disease variant","Dyskeratosis congenita","Microphthalmia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"14.7","Excitatory neurons":"12.9","Gastric mucus-secreting cells":"5.1","Inhibitory neurons":"10.9","Oligodendrocyte precursor cells":"13.6","Oligodendrocytes":"5.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"65.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046723","HPA058011"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Plasma membrane","Mitochondria","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Plasma membrane","Mitochondria","Cytosol"],"Antibody RRID":{"HPA046723":"AB_10960288","HPA058011":"AB_2683578"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.45e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.52e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.2","Tissue RNA - adrenal gland [nTPM]":"8.7","Tissue RNA - amygdala [nTPM]":"4.3","Tissue RNA - appendix [nTPM]":"3.4","Tissue RNA - basal ganglia [nTPM]":"3.9","Tissue RNA - bone marrow [nTPM]":"10.4","Tissue RNA - breast [nTPM]":"7.6","Tissue RNA - cerebellum [nTPM]":"3.2","Tissue RNA - cerebral cortex [nTPM]":"4.6","Tissue RNA - cervix [nTPM]":"7.7","Tissue RNA - choroid plexus [nTPM]":"4.4","Tissue RNA - colon [nTPM]":"6.5","Tissue RNA - duodenum [nTPM]":"6.9","Tissue RNA - endometrium 1 [nTPM]":"8.4","Tissue RNA - epididymis [nTPM]":"8.2","Tissue RNA - esophagus [nTPM]":"11.4","Tissue RNA - fallopian tube [nTPM]":"9.6","Tissue RNA - gallbladder [nTPM]":"7.1","Tissue RNA - heart muscle [nTPM]":"8.5","Tissue RNA - hippocampal formation [nTPM]":"4.0","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"5.2","Tissue RNA - liver [nTPM]":"15.9","Tissue RNA - lung [nTPM]":"5.9","Tissue RNA - lymph node [nTPM]":"1.9","Tissue RNA - medulla oblongata [nTPM]":"4.4","Tissue RNA - midbrain [nTPM]":"4.2","Tissue RNA - ovary [nTPM]":"12.9","Tissue RNA - pancreas [nTPM]":"5.7","Tissue RNA - parathyroid gland [nTPM]":"4.8","Tissue RNA - pituitary gland [nTPM]":"6.0","Tissue RNA - placenta [nTPM]":"3.1","Tissue RNA - pons [nTPM]":"6.2","Tissue RNA - prostate [nTPM]":"8.0","Tissue RNA - rectum [nTPM]":"3.3","Tissue RNA - retina [nTPM]":"3.0","Tissue RNA - salivary gland [nTPM]":"6.2","Tissue RNA - seminal vesicle [nTPM]":"8.6","Tissue RNA - skeletal muscle [nTPM]":"30.4","Tissue RNA - skin 1 [nTPM]":"6.8","Tissue RNA - small intestine [nTPM]":"6.3","Tissue RNA - smooth muscle [nTPM]":"7.9","Tissue RNA - spinal cord [nTPM]":"4.1","Tissue RNA - spleen [nTPM]":"3.9","Tissue RNA - stomach 1 [nTPM]":"7.9","Tissue RNA - testis [nTPM]":"18.0","Tissue RNA - thalamus [nTPM]":"5.7","Tissue RNA - thymus [nTPM]":"2.6","Tissue RNA - thyroid gland [nTPM]":"10.7","Tissue RNA - tongue [nTPM]":"9.8","Tissue RNA - tonsil [nTPM]":"2.9","Tissue RNA - urinary bladder [nTPM]":"14.9","Tissue RNA - vagina [nTPM]":"7.9","Tissue RNA - white matter [nTPM]":"5.0","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"22.9","Cell RNA - AF22 [nTPM]":"4.7","Cell RNA - AN3-CA [nTPM]":"28.8","Cell RNA - ASC diff [nTPM]":"30.8","Cell RNA - ASC TERT1 [nTPM]":"11.1","Cell RNA - BEWO [nTPM]":"27.6","Cell RNA - BJ [nTPM]":"8.5","Cell RNA - BJ hTERT+ [nTPM]":"7.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.2","Cell RNA - CACO-2 [nTPM]":"35.5","Cell RNA - CAPAN-2 [nTPM]":"5.0","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"42.8","Cell RNA - fHDF\/TERT166 [nTPM]":"8.6","Cell RNA - GAMG [nTPM]":"5.0","Cell RNA - HaCaT [nTPM]":"49.1","Cell RNA - HAP1 [nTPM]":"0.6","Cell RNA - HBEC3-KT [nTPM]":"3.6","Cell RNA - HBF TERT88 [nTPM]":"3.0","Cell RNA - HDLM-2 [nTPM]":"15.0","Cell RNA - HEK 293 [nTPM]":"4.7","Cell RNA - HEL [nTPM]":"36.3","Cell RNA - HeLa [nTPM]":"24.9","Cell RNA - Hep G2 [nTPM]":"65.8","Cell RNA - HHSteC [nTPM]":"37.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"12.0","Cell RNA - HSkMC [nTPM]":"16.3","Cell RNA - hTCEpi [nTPM]":"4.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.2","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"13.9","Cell RNA - HUVEC TERT2 [nTPM]":"16.3","Cell RNA - JURKAT [nTPM]":"4.8","Cell RNA - K-562 [nTPM]":"31.4","Cell RNA - Karpas-707 [nTPM]":"4.4","Cell RNA - LHCN-M2 [nTPM]":"6.3","Cell RNA - MCF7 [nTPM]":"12.0","Cell RNA - MOLT-4 [nTPM]":"2.3","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"7.2","Cell RNA - OE19 [nTPM]":"53.6","Cell RNA - PC-3 [nTPM]":"9.2","Cell RNA - REH [nTPM]":"12.3","Cell RNA - RH-30 [nTPM]":"14.3","Cell RNA - RPMI-8226 [nTPM]":"1.6","Cell RNA - RPTEC TERT1 [nTPM]":"5.1","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"16.6","Cell RNA - SH-SY5Y [nTPM]":"17.8","Cell RNA - SiHa [nTPM]":"17.6","Cell RNA - SK-BR-3 [nTPM]":"41.4","Cell RNA - SK-MEL-30 [nTPM]":"18.7","Cell RNA - SuSa [nTPM]":"17.4","Cell RNA - T-47d [nTPM]":"12.4","Cell RNA - THP-1 [nTPM]":"0.8","Cell RNA - TIME [nTPM]":"7.5","Cell RNA - U-138 MG [nTPM]":"12.5","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"16.9","Cell RNA - U-251 MG [nTPM]":"10.3","Cell RNA - U-266\/70 [nTPM]":"11.2","Cell RNA - U-266\/84 [nTPM]":"9.6","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"14.0","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"17.0","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.8","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"2.3","Blood RNA - T-reg [nTPM]":"0.5","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"4.3","Brain RNA - basal ganglia [nTPM]":"3.9","Brain RNA - cerebellum [nTPM]":"3.2","Brain RNA - cerebral cortex [nTPM]":"4.6","Brain RNA - hippocampal formation [nTPM]":"4.0","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"4.4","Brain RNA - midbrain [nTPM]":"4.2","Brain RNA - pons [nTPM]":"6.2","Brain RNA - spinal cord [nTPM]":"4.1","Brain RNA - thalamus [nTPM]":"5.7","Brain RNA - white matter [nTPM]":"5.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"ADAR","Gene synonym":["ADAR1","G1P1","IFI4"],"Ensembl":"ENSG00000160710","Gene description":"Adenosine deaminase RNA specific","Uniprot":["P55265"],"Chromosome":"1","Position":"154581695-154628013","Protein class":["Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Antiviral defense","Immunity","Innate immunity","mRNA processing","RNA-mediated gene silencing"],"Molecular function":["DNA-binding","Hydrolase","RNA-binding"],"Disease involvement":["Aicardi-Goutieres syndrome","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003890","HPA051519","CAB056157"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB056157":"AB_2665578","HPA003890":"AB_1078103","HPA051519":"AB_2681520"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.30e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-2"},"Tissue RNA - adipose tissue [nTPM]":"41.9","Tissue RNA - adrenal gland [nTPM]":"44.7","Tissue RNA - amygdala [nTPM]":"30.4","Tissue RNA - appendix [nTPM]":"57.2","Tissue RNA - basal ganglia [nTPM]":"29.9","Tissue RNA - bone marrow [nTPM]":"47.1","Tissue RNA - breast [nTPM]":"41.1","Tissue RNA - cerebellum [nTPM]":"18.0","Tissue RNA - cerebral cortex [nTPM]":"35.1","Tissue RNA - cervix [nTPM]":"49.4","Tissue RNA - choroid plexus [nTPM]":"16.3","Tissue RNA - colon [nTPM]":"42.9","Tissue RNA - duodenum [nTPM]":"46.4","Tissue RNA - endometrium 1 [nTPM]":"50.2","Tissue RNA - epididymis [nTPM]":"26.3","Tissue RNA - esophagus [nTPM]":"37.9","Tissue RNA - fallopian tube [nTPM]":"50.3","Tissue RNA - gallbladder [nTPM]":"45.6","Tissue RNA - heart muscle [nTPM]":"36.1","Tissue RNA - hippocampal formation [nTPM]":"31.5","Tissue RNA - hypothalamus [nTPM]":"40.0","Tissue RNA - kidney [nTPM]":"51.7","Tissue RNA - liver [nTPM]":"56.1","Tissue RNA - lung [nTPM]":"54.6","Tissue RNA - lymph node [nTPM]":"66.1","Tissue RNA - medulla oblongata [nTPM]":"32.1","Tissue RNA - midbrain [nTPM]":"33.8","Tissue RNA - ovary [nTPM]":"54.9","Tissue RNA - pancreas [nTPM]":"40.6","Tissue RNA - parathyroid gland [nTPM]":"62.8","Tissue RNA - pituitary gland [nTPM]":"53.9","Tissue RNA - placenta [nTPM]":"46.5","Tissue RNA - pons [nTPM]":"34.8","Tissue RNA - prostate [nTPM]":"42.8","Tissue RNA - rectum [nTPM]":"44.4","Tissue RNA - retina [nTPM]":"47.9","Tissue RNA - salivary gland [nTPM]":"59.4","Tissue RNA - seminal vesicle [nTPM]":"43.0","Tissue RNA - skeletal muscle [nTPM]":"18.8","Tissue RNA - skin 1 [nTPM]":"39.9","Tissue RNA - small intestine [nTPM]":"52.8","Tissue RNA - smooth muscle [nTPM]":"56.6","Tissue RNA - spinal cord [nTPM]":"39.2","Tissue RNA - spleen [nTPM]":"73.5","Tissue RNA - stomach 1 [nTPM]":"40.3","Tissue RNA - testis [nTPM]":"34.4","Tissue RNA - thalamus [nTPM]":"37.8","Tissue RNA - thymus [nTPM]":"85.2","Tissue RNA - thyroid gland [nTPM]":"47.1","Tissue RNA - tongue [nTPM]":"27.6","Tissue RNA - tonsil [nTPM]":"65.0","Tissue RNA - urinary bladder [nTPM]":"50.5","Tissue RNA - vagina [nTPM]":"40.0","Tissue RNA - white matter [nTPM]":"25.5","Cell RNA - A-431 [nTPM]":"93.2","Cell RNA - A549 [nTPM]":"103.1","Cell RNA - AF22 [nTPM]":"84.4","Cell RNA - AN3-CA [nTPM]":"104.8","Cell RNA - ASC diff [nTPM]":"87.4","Cell RNA - ASC TERT1 [nTPM]":"88.5","Cell RNA - BEWO [nTPM]":"97.8","Cell RNA - BJ [nTPM]":"59.5","Cell RNA - BJ hTERT+ [nTPM]":"132.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"209.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"183.4","Cell RNA - CACO-2 [nTPM]":"87.8","Cell RNA - CAPAN-2 [nTPM]":"85.3","Cell RNA - Daudi [nTPM]":"162.6","Cell RNA - EFO-21 [nTPM]":"97.7","Cell RNA - fHDF\/TERT166 [nTPM]":"98.7","Cell RNA - GAMG [nTPM]":"112.4","Cell RNA - HaCaT [nTPM]":"85.4","Cell RNA - HAP1 [nTPM]":"111.9","Cell RNA - HBEC3-KT [nTPM]":"115.5","Cell RNA - HBF TERT88 [nTPM]":"109.8","Cell RNA - HDLM-2 [nTPM]":"159.1","Cell RNA - HEK 293 [nTPM]":"52.3","Cell RNA - HEL [nTPM]":"84.9","Cell RNA - HeLa [nTPM]":"66.2","Cell RNA - Hep G2 [nTPM]":"48.4","Cell RNA - HHSteC [nTPM]":"96.7","Cell RNA - HL-60 [nTPM]":"122.8","Cell RNA - HMC-1 [nTPM]":"83.8","Cell RNA - HSkMC [nTPM]":"86.2","Cell RNA - hTCEpi [nTPM]":"84.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"100.4","Cell RNA - hTERT-HME1 [nTPM]":"104.1","Cell RNA - hTERT-RPE1 [nTPM]":"81.2","Cell RNA - HUVEC TERT2 [nTPM]":"104.5","Cell RNA - JURKAT [nTPM]":"112.4","Cell RNA - K-562 [nTPM]":"82.4","Cell RNA - Karpas-707 [nTPM]":"111.6","Cell RNA - LHCN-M2 [nTPM]":"72.0","Cell RNA - MCF7 [nTPM]":"107.8","Cell RNA - MOLT-4 [nTPM]":"165.0","Cell RNA - NB-4 [nTPM]":"43.3","Cell RNA - NTERA-2 [nTPM]":"139.7","Cell RNA - OE19 [nTPM]":"125.5","Cell RNA - PC-3 [nTPM]":"74.6","Cell RNA - REH [nTPM]":"140.1","Cell RNA - RH-30 [nTPM]":"74.2","Cell RNA - RPMI-8226 [nTPM]":"131.2","Cell RNA - RPTEC TERT1 [nTPM]":"67.6","Cell RNA - RT4 [nTPM]":"106.1","Cell RNA - SCLC-21H [nTPM]":"84.8","Cell RNA - SH-SY5Y [nTPM]":"100.2","Cell RNA - SiHa [nTPM]":"104.4","Cell RNA - SK-BR-3 [nTPM]":"167.9","Cell RNA - SK-MEL-30 [nTPM]":"126.2","Cell RNA - SuSa [nTPM]":"128.1","Cell RNA - T-47d [nTPM]":"113.4","Cell RNA - THP-1 [nTPM]":"148.2","Cell RNA - TIME [nTPM]":"94.3","Cell RNA - U-138 MG [nTPM]":"67.5","Cell RNA - U-2 OS [nTPM]":"68.5","Cell RNA - U-2197 [nTPM]":"58.8","Cell RNA - U-251 MG [nTPM]":"71.5","Cell RNA - U-266\/70 [nTPM]":"132.9","Cell RNA - U-266\/84 [nTPM]":"179.0","Cell RNA - U-698 [nTPM]":"177.6","Cell RNA - U-87 MG [nTPM]":"70.2","Cell RNA - U-937 [nTPM]":"78.4","Cell RNA - WM-115 [nTPM]":"81.0","Blood RNA - basophil [nTPM]":"7.8","Blood RNA - classical monocyte [nTPM]":"8.1","Blood RNA - eosinophil [nTPM]":"15.0","Blood RNA - gdT-cell [nTPM]":"10.8","Blood RNA - intermediate monocyte [nTPM]":"9.9","Blood RNA - MAIT T-cell [nTPM]":"10.2","Blood RNA - memory B-cell [nTPM]":"9.0","Blood RNA - memory CD4 T-cell [nTPM]":"10.6","Blood RNA - memory CD8 T-cell [nTPM]":"11.2","Blood RNA - myeloid DC [nTPM]":"7.8","Blood RNA - naive B-cell [nTPM]":"5.8","Blood RNA - naive CD4 T-cell [nTPM]":"9.8","Blood RNA - naive CD8 T-cell [nTPM]":"10.0","Blood RNA - neutrophil [nTPM]":"29.1","Blood RNA - NK-cell [nTPM]":"8.6","Blood RNA - non-classical monocyte [nTPM]":"9.4","Blood RNA - plasmacytoid DC [nTPM]":"6.3","Blood RNA - T-reg [nTPM]":"9.1","Blood RNA - total PBMC [nTPM]":"7.4","Brain RNA - amygdala [nTPM]":"30.4","Brain RNA - basal ganglia [nTPM]":"29.9","Brain RNA - cerebellum [nTPM]":"18.0","Brain RNA - cerebral cortex [nTPM]":"35.1","Brain RNA - hippocampal formation [nTPM]":"31.5","Brain RNA - hypothalamus [nTPM]":"40.0","Brain RNA - medulla oblongata [nTPM]":"32.1","Brain RNA - midbrain [nTPM]":"33.8","Brain RNA - pons [nTPM]":"34.8","Brain RNA - spinal cord [nTPM]":"39.2","Brain RNA - thalamus [nTPM]":"37.8","Brain RNA - white matter [nTPM]":"25.5","Single Cell Type RNA - Adipocytes [nTPM]":"73.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"83.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"51.2","Single Cell Type RNA - Astrocytes [nTPM]":"37.5","Single Cell Type RNA - B-cells [nTPM]":"80.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"33.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"39.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"39.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"32.5","Single Cell Type RNA - Bipolar cells [nTPM]":"94.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"43.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"36.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"22.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"45.8","Single Cell Type RNA - Club cells [nTPM]":"44.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"95.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"41.2","Single Cell Type RNA - dendritic cells [nTPM]":"103.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"73.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"49.2","Single Cell Type RNA - Early spermatids [nTPM]":"4.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"48.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"61.0","Single Cell Type RNA - Endothelial cells [nTPM]":"86.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"63.1","Single Cell Type RNA - Erythroid cells [nTPM]":"45.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"44.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"66.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"57.8","Single Cell Type RNA - Fibroblasts [nTPM]":"49.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"56.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"52.4","Single Cell Type RNA - granulocytes [nTPM]":"62.1","Single Cell Type RNA - Granulosa cells [nTPM]":"88.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"84.9","Single Cell Type RNA - Hepatocytes [nTPM]":"93.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"53.5","Single Cell Type RNA - Horizontal cells [nTPM]":"168.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"53.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"53.9","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"104.1","Single Cell Type RNA - Langerhans cells [nTPM]":"43.9","Single Cell Type RNA - Late spermatids [nTPM]":"13.1","Single Cell Type RNA - Leydig cells [nTPM]":"73.7","Single Cell Type RNA - Macrophages [nTPM]":"78.0","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"32.8","Single Cell Type RNA - monocytes [nTPM]":"110.2","Single Cell Type RNA - Muller glia cells [nTPM]":"37.9","Single Cell Type RNA - NK-cells [nTPM]":"126.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"38.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"39.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"69.6","Single Cell Type RNA - Paneth cells [nTPM]":"62.7","Single Cell Type RNA - Peritubular cells [nTPM]":"59.0","Single Cell Type RNA - Plasma cells [nTPM]":"87.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"61.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"86.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"42.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"50.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"80.2","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"40.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"45.2","Single Cell Type RNA - Spermatocytes [nTPM]":"11.4","Single Cell Type RNA - Spermatogonia [nTPM]":"35.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"37.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"40.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.5","Single Cell Type RNA - T-cells [nTPM]":"85.6","Single Cell Type RNA - Theca cells [nTPM]":"66.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"56.2","Single Cell Type RNA - Urothelial cells [nTPM]":"53.8"},{"Gene":"ADGRE2","Gene synonym":["CD312","EMR2"],"Ensembl":"ENSG00000127507","Gene description":"Adhesion G protein-coupled receptor E2","Uniprot":["Q9UHX3"],"Chromosome":"19","Position":"14732392-14778560","Protein class":["CD markers","Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Cell adhesion","Inflammatory response"],"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"19.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"granulocytes":"47.9","Kupffer cells":"69.4","Macrophages":"73.2","monocytes":"49.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"70.0","eosinophil":"74.7","intermediate monocyte":"46.9","neutrophil":"55.7","non-classical monocyte":"89.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"74.7","monocytes":"89.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"11.8","HMC-1":"18.3","NB-4":"11.5","RPMI-8226":"8.4","U-937":"14.9"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055200"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA055200":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.35e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Tissue RNA - adipose tissue [nTPM]":"4.9","Tissue RNA - adrenal gland [nTPM]":"1.5","Tissue RNA - amygdala [nTPM]":"1.0","Tissue RNA - appendix [nTPM]":"19.4","Tissue RNA - basal ganglia [nTPM]":"1.3","Tissue RNA - bone marrow [nTPM]":"6.9","Tissue RNA - breast [nTPM]":"1.8","Tissue RNA - cerebellum [nTPM]":"1.2","Tissue RNA - cerebral cortex [nTPM]":"2.1","Tissue RNA - cervix [nTPM]":"0.9","Tissue RNA - choroid plexus [nTPM]":"1.3","Tissue RNA - colon [nTPM]":"1.4","Tissue RNA - duodenum [nTPM]":"1.9","Tissue RNA - endometrium 1 [nTPM]":"0.7","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"0.9","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"2.5","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"1.0","Tissue RNA - hypothalamus [nTPM]":"1.5","Tissue RNA - kidney [nTPM]":"2.1","Tissue RNA - liver [nTPM]":"2.0","Tissue RNA - lung [nTPM]":"4.2","Tissue RNA - lymph node [nTPM]":"3.0","Tissue RNA - medulla oblongata [nTPM]":"2.5","Tissue RNA - midbrain [nTPM]":"1.6","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"1.1","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"1.6","Tissue RNA - pons [nTPM]":"2.2","Tissue RNA - prostate [nTPM]":"1.1","Tissue RNA - rectum [nTPM]":"1.9","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"2.8","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"2.0","Tissue RNA - small intestine [nTPM]":"2.3","Tissue RNA - smooth muscle [nTPM]":"1.6","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"15.6","Tissue RNA - stomach 1 [nTPM]":"1.5","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"1.8","Tissue RNA - thymus [nTPM]":"2.4","Tissue RNA - thyroid gland [nTPM]":"0.6","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"2.2","Tissue RNA - urinary bladder [nTPM]":"5.4","Tissue RNA - vagina [nTPM]":"0.9","Tissue RNA - white matter [nTPM]":"2.4","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"1.2","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"1.2","Cell RNA - BJ [nTPM]":"0.9","Cell RNA - BJ hTERT+ [nTPM]":"1.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.7","Cell RNA - GAMG [nTPM]":"2.3","Cell RNA - HaCaT [nTPM]":"1.9","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"11.8","Cell RNA - HeLa [nTPM]":"3.8","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.5","Cell RNA - HL-60 [nTPM]":"4.3","Cell RNA - HMC-1 [nTPM]":"18.3","Cell RNA - HSkMC [nTPM]":"0.9","Cell RNA - hTCEpi [nTPM]":"1.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.1","Cell RNA - hTERT-HME1 [nTPM]":"0.6","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"1.0","Cell RNA - K-562 [nTPM]":"2.7","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"1.3","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"1.5","Cell RNA - NB-4 [nTPM]":"11.5","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.8","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"1.5","Cell RNA - RPMI-8226 [nTPM]":"8.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"2.4","Cell RNA - SK-BR-3 [nTPM]":"2.0","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"5.4","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"1.1","Cell RNA - U-937 [nTPM]":"14.9","Cell RNA - WM-115 [nTPM]":"0.6","Blood RNA - basophil [nTPM]":"70.0","Blood RNA - classical monocyte [nTPM]":"13.9","Blood RNA - eosinophil [nTPM]":"74.7","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"46.9","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"9.3","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"55.7","Blood RNA - NK-cell [nTPM]":"3.3","Blood RNA - non-classical monocyte [nTPM]":"89.9","Blood RNA - plasmacytoid DC [nTPM]":"1.9","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"7.3","Brain RNA - amygdala [nTPM]":"1.0","Brain RNA - basal ganglia [nTPM]":"1.3","Brain RNA - cerebellum [nTPM]":"1.2","Brain RNA - cerebral cortex [nTPM]":"2.1","Brain RNA - hippocampal formation [nTPM]":"1.0","Brain RNA - hypothalamus [nTPM]":"1.5","Brain RNA - medulla oblongata [nTPM]":"2.5","Brain RNA - midbrain [nTPM]":"1.6","Brain RNA - pons [nTPM]":"2.2","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"1.8","Brain RNA - white matter [nTPM]":"2.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"1.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"12.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.5","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"1.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.9","Single Cell Type RNA - granulocytes [nTPM]":"47.9","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"69.4","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"73.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"49.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"2.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"3.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"3.0"},{"Gene":"AP1S3","Gene synonym":[],"Ensembl":"ENSG00000152056","Gene description":"Adaptor related protein complex 1 subunit sigma 3","Uniprot":["Q96PC3"],"Chromosome":"2","Position":"223751686-223838027","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Protein transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"52.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"64.6","Cytotrophoblasts":"48.2","Pancreatic endocrine cells":"44.2","Urothelial cells":"69.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"4.9","dendritic cells":"4.0","granulocytes":"4.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"151.1","RPTEC TERT1":"56.8","RT4":"52.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066782"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA066782":"AB_2685720"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.45e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.52e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.36e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.08e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.61e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.7","Tissue RNA - adrenal gland [nTPM]":"0.8","Tissue RNA - amygdala [nTPM]":"3.4","Tissue RNA - appendix [nTPM]":"3.3","Tissue RNA - basal ganglia [nTPM]":"3.2","Tissue RNA - bone marrow [nTPM]":"4.0","Tissue RNA - breast [nTPM]":"2.1","Tissue RNA - cerebellum [nTPM]":"3.9","Tissue RNA - cerebral cortex [nTPM]":"3.5","Tissue RNA - cervix [nTPM]":"2.2","Tissue RNA - choroid plexus [nTPM]":"0.5","Tissue RNA - colon [nTPM]":"2.7","Tissue RNA - duodenum [nTPM]":"5.3","Tissue RNA - endometrium 1 [nTPM]":"0.9","Tissue RNA - epididymis [nTPM]":"52.8","Tissue RNA - esophagus [nTPM]":"4.8","Tissue RNA - fallopian tube [nTPM]":"2.3","Tissue RNA - gallbladder [nTPM]":"5.2","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"2.8","Tissue RNA - hypothalamus [nTPM]":"3.0","Tissue RNA - kidney [nTPM]":"5.6","Tissue RNA - liver [nTPM]":"1.4","Tissue RNA - lung [nTPM]":"4.7","Tissue RNA - lymph node [nTPM]":"4.2","Tissue RNA - medulla oblongata [nTPM]":"2.0","Tissue RNA - midbrain [nTPM]":"1.6","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"2.4","Tissue RNA - parathyroid gland [nTPM]":"3.8","Tissue RNA - pituitary gland [nTPM]":"1.1","Tissue RNA - placenta [nTPM]":"6.6","Tissue RNA - pons [nTPM]":"1.5","Tissue RNA - prostate [nTPM]":"2.9","Tissue RNA - rectum [nTPM]":"2.6","Tissue RNA - retina [nTPM]":"5.7","Tissue RNA - salivary gland [nTPM]":"1.6","Tissue RNA - seminal vesicle [nTPM]":"5.4","Tissue RNA - skeletal muscle [nTPM]":"0.9","Tissue RNA - skin 1 [nTPM]":"1.9","Tissue RNA - small intestine [nTPM]":"5.0","Tissue RNA - smooth muscle [nTPM]":"0.7","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"2.8","Tissue RNA - stomach 1 [nTPM]":"9.8","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"3.2","Tissue RNA - thymus [nTPM]":"1.6","Tissue RNA - thyroid gland [nTPM]":"14.4","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"5.2","Tissue RNA - urinary bladder [nTPM]":"8.1","Tissue RNA - vagina [nTPM]":"1.2","Tissue RNA - white matter [nTPM]":"2.1","Cell RNA - A-431 [nTPM]":"28.7","Cell RNA - A549 [nTPM]":"17.7","Cell RNA - AF22 [nTPM]":"2.4","Cell RNA - AN3-CA [nTPM]":"12.0","Cell RNA - ASC diff [nTPM]":"1.5","Cell RNA - ASC TERT1 [nTPM]":"0.6","Cell RNA - BEWO [nTPM]":"13.5","Cell RNA - BJ [nTPM]":"11.5","Cell RNA - BJ hTERT+ [nTPM]":"2.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.2","Cell RNA - CACO-2 [nTPM]":"151.1","Cell RNA - CAPAN-2 [nTPM]":"21.8","Cell RNA - Daudi [nTPM]":"11.0","Cell RNA - EFO-21 [nTPM]":"8.0","Cell RNA - fHDF\/TERT166 [nTPM]":"1.7","Cell RNA - GAMG [nTPM]":"5.8","Cell RNA - HaCaT [nTPM]":"43.8","Cell RNA - HAP1 [nTPM]":"6.4","Cell RNA - HBEC3-KT [nTPM]":"30.3","Cell RNA - HBF TERT88 [nTPM]":"6.8","Cell RNA - HDLM-2 [nTPM]":"15.3","Cell RNA - HEK 293 [nTPM]":"8.9","Cell RNA - HEL [nTPM]":"1.2","Cell RNA - HeLa [nTPM]":"33.7","Cell RNA - Hep G2 [nTPM]":"15.7","Cell RNA - HHSteC [nTPM]":"0.6","Cell RNA - HL-60 [nTPM]":"3.4","Cell RNA - HMC-1 [nTPM]":"1.3","Cell RNA - HSkMC [nTPM]":"0.6","Cell RNA - hTCEpi [nTPM]":"31.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.1","Cell RNA - hTERT-HME1 [nTPM]":"30.1","Cell RNA - hTERT-RPE1 [nTPM]":"11.2","Cell RNA - HUVEC TERT2 [nTPM]":"3.4","Cell RNA - JURKAT [nTPM]":"5.8","Cell RNA - K-562 [nTPM]":"1.8","Cell RNA - Karpas-707 [nTPM]":"2.9","Cell RNA - LHCN-M2 [nTPM]":"2.9","Cell RNA - MCF7 [nTPM]":"12.3","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"0.9","Cell RNA - NTERA-2 [nTPM]":"3.8","Cell RNA - OE19 [nTPM]":"32.8","Cell RNA - PC-3 [nTPM]":"15.5","Cell RNA - REH [nTPM]":"4.3","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"4.5","Cell RNA - RPTEC TERT1 [nTPM]":"56.8","Cell RNA - RT4 [nTPM]":"52.1","Cell RNA - SCLC-21H [nTPM]":"7.4","Cell RNA - SH-SY5Y [nTPM]":"2.1","Cell RNA - SiHa [nTPM]":"5.4","Cell RNA - SK-BR-3 [nTPM]":"11.8","Cell RNA - SK-MEL-30 [nTPM]":"3.8","Cell RNA - SuSa [nTPM]":"6.1","Cell RNA - T-47d [nTPM]":"5.0","Cell RNA - THP-1 [nTPM]":"6.3","Cell RNA - TIME [nTPM]":"2.0","Cell RNA - U-138 MG [nTPM]":"1.6","Cell RNA - U-2 OS [nTPM]":"4.6","Cell RNA - U-2197 [nTPM]":"3.1","Cell RNA - U-251 MG [nTPM]":"9.2","Cell RNA - U-266\/70 [nTPM]":"10.2","Cell RNA - U-266\/84 [nTPM]":"9.0","Cell RNA - U-698 [nTPM]":"28.2","Cell RNA - U-87 MG [nTPM]":"4.4","Cell RNA - U-937 [nTPM]":"2.0","Cell RNA - WM-115 [nTPM]":"6.0","Blood RNA - basophil [nTPM]":"4.9","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"4.9","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"1.2","Blood RNA - naive B-cell [nTPM]":"2.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"4.0","Blood RNA - T-reg [nTPM]":"1.0","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"3.4","Brain RNA - basal ganglia [nTPM]":"3.2","Brain RNA - cerebellum [nTPM]":"3.9","Brain RNA - cerebral cortex [nTPM]":"3.5","Brain RNA - hippocampal formation [nTPM]":"2.8","Brain RNA - hypothalamus [nTPM]":"3.0","Brain RNA - medulla oblongata [nTPM]":"2.0","Brain RNA - midbrain [nTPM]":"1.6","Brain RNA - pons [nTPM]":"1.5","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"3.2","Brain RNA - white matter [nTPM]":"2.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.7","Single Cell Type RNA - Astrocytes [nTPM]":"8.8","Single Cell Type RNA - B-cells [nTPM]":"24.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"3.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"15.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"64.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"48.2","Single Cell Type RNA - dendritic cells [nTPM]":"13.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"17.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.1","Single Cell Type RNA - Endothelial cells [nTPM]":"2.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.4","Single Cell Type RNA - Fibroblasts [nTPM]":"3.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.1","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.7","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.6","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"38.1","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"7.5","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"7.4","Single Cell Type RNA - Muller glia cells [nTPM]":"1.9","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"44.2","Single Cell Type RNA - Paneth cells [nTPM]":"4.6","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"10.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"26.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.1","Single Cell Type RNA - T-cells [nTPM]":"6.9","Single Cell Type RNA - Theca cells [nTPM]":"1.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.7","Single Cell Type RNA - Urothelial cells [nTPM]":"69.6"},{"Gene":"APCDD1","Gene synonym":["B7323"],"Ensembl":"ENSG00000154856","Gene description":"APC down-regulated 1","Uniprot":["Q8J025"],"Chromosome":"18","Position":"10454635-10489949","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":null,"Disease involvement":["Disease variant","Hypotrichosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"129.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"120.5","Cholangiocytes":"85.8","Endometrial stromal cells":"429.5","Melanocytes":"80.0","Oligodendrocyte precursor cells":"110.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"32.0","BJ hTERT+":"70.4","HaCaT":"43.0","HHSteC":"18.9","HSkMC":"39.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 36: Stromal cells - Cell proliferation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.39e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.23e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-2"},"Tissue RNA - adipose tissue [nTPM]":"52.5","Tissue RNA - adrenal gland [nTPM]":"14.2","Tissue RNA - amygdala [nTPM]":"33.4","Tissue RNA - appendix [nTPM]":"6.9","Tissue RNA - basal ganglia [nTPM]":"31.1","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"31.4","Tissue RNA - cerebellum [nTPM]":"30.4","Tissue RNA - cerebral cortex [nTPM]":"34.3","Tissue RNA - cervix [nTPM]":"35.6","Tissue RNA - choroid plexus [nTPM]":"17.0","Tissue RNA - colon [nTPM]":"12.8","Tissue RNA - duodenum [nTPM]":"3.5","Tissue RNA - endometrium 1 [nTPM]":"32.7","Tissue RNA - epididymis [nTPM]":"15.6","Tissue RNA - esophagus [nTPM]":"27.7","Tissue RNA - fallopian tube [nTPM]":"32.6","Tissue RNA - gallbladder [nTPM]":"21.9","Tissue RNA - heart muscle [nTPM]":"32.0","Tissue RNA - hippocampal formation [nTPM]":"39.5","Tissue RNA - hypothalamus [nTPM]":"33.0","Tissue RNA - kidney [nTPM]":"6.2","Tissue RNA - liver [nTPM]":"1.4","Tissue RNA - lung [nTPM]":"13.2","Tissue RNA - lymph node [nTPM]":"1.2","Tissue RNA - medulla oblongata [nTPM]":"33.0","Tissue RNA - midbrain [nTPM]":"36.9","Tissue RNA - ovary [nTPM]":"33.0","Tissue RNA - pancreas [nTPM]":"8.9","Tissue RNA - parathyroid gland [nTPM]":"3.4","Tissue RNA - pituitary gland [nTPM]":"3.2","Tissue RNA - placenta [nTPM]":"26.9","Tissue RNA - pons [nTPM]":"29.8","Tissue RNA - prostate [nTPM]":"33.3","Tissue RNA - rectum [nTPM]":"13.2","Tissue RNA - retina [nTPM]":"1.6","Tissue RNA - salivary gland [nTPM]":"10.6","Tissue RNA - seminal vesicle [nTPM]":"14.1","Tissue RNA - skeletal muscle [nTPM]":"7.3","Tissue RNA - skin 1 [nTPM]":"129.8","Tissue RNA - small intestine [nTPM]":"14.5","Tissue RNA - smooth muscle [nTPM]":"10.6","Tissue RNA - spinal cord [nTPM]":"26.6","Tissue RNA - spleen [nTPM]":"4.1","Tissue RNA - stomach 1 [nTPM]":"23.8","Tissue RNA - testis [nTPM]":"2.7","Tissue RNA - thalamus [nTPM]":"33.8","Tissue RNA - thymus [nTPM]":"2.2","Tissue RNA - thyroid gland [nTPM]":"5.3","Tissue RNA - tongue [nTPM]":"18.5","Tissue RNA - tonsil [nTPM]":"4.7","Tissue RNA - urinary bladder [nTPM]":"36.6","Tissue RNA - vagina [nTPM]":"35.5","Tissue RNA - white matter [nTPM]":"29.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"32.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"5.4","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"2.4","Cell RNA - BJ hTERT+ [nTPM]":"70.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.9","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"13.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"43.0","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"3.3","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.6","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.7","Cell RNA - HHSteC [nTPM]":"18.9","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"39.3","Cell RNA - hTCEpi [nTPM]":"1.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.5","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"3.1","Cell RNA - MCF7 [nTPM]":"2.1","Cell RNA - MOLT-4 [nTPM]":"1.8","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"5.2","Cell RNA - OE19 [nTPM]":"15.3","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.9","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"0.8","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"3.6","Cell RNA - SuSa [nTPM]":"2.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"3.8","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"4.8","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"33.4","Brain RNA - basal ganglia [nTPM]":"31.1","Brain RNA - cerebellum [nTPM]":"30.4","Brain RNA - cerebral cortex [nTPM]":"34.3","Brain RNA - hippocampal formation [nTPM]":"39.5","Brain RNA - hypothalamus [nTPM]":"33.0","Brain RNA - medulla oblongata [nTPM]":"33.0","Brain RNA - midbrain [nTPM]":"36.9","Brain RNA - pons [nTPM]":"29.8","Brain RNA - spinal cord [nTPM]":"26.6","Brain RNA - thalamus [nTPM]":"33.8","Brain RNA - white matter [nTPM]":"29.6","Single Cell Type RNA - Adipocytes [nTPM]":"3.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.6","Single Cell Type RNA - Astrocytes [nTPM]":"120.5","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"65.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"4.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"85.8","Single Cell Type RNA - Club cells [nTPM]":"2.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.4","Single Cell Type RNA - dendritic cells [nTPM]":"1.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"11.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"28.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"429.5","Single Cell Type RNA - Endothelial cells [nTPM]":"47.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"64.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.9","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.1","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"35.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"8.7","Single Cell Type RNA - Macrophages [nTPM]":"3.3","Single Cell Type RNA - Melanocytes [nTPM]":"80.0","Single Cell Type RNA - Microglial cells [nTPM]":"67.5","Single Cell Type RNA - monocytes [nTPM]":"1.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"110.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"15.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"37.6","Single Cell Type RNA - Plasma cells [nTPM]":"1.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.2","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"28.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"53.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"4.2","Single Cell Type RNA - Theca cells [nTPM]":"1.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.4","Single Cell Type RNA - Urothelial cells [nTPM]":"4.5"},{"Gene":"BANK1","Gene synonym":["BANK","FLJ20706"],"Ensembl":"ENSG00000153064","Gene description":"B cell scaffold protein with ankyrin repeats 1","Uniprot":["Q8NDB2"],"Chromosome":"4","Position":"101411286-102074812","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["B-cell activation"],"Molecular function":null,"Disease involvement":["Systemic lupus erythematosus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"24.2","lymphoid tissue":"96.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"B-cells":"455.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"6.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"14","RNA blood cell specific nTPM":{"memory B-cell":"310.4","naive B-cell":"253.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"B-cells":"310.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"13.6","HEL":"10.6","HL-60":"9.6","U-266\/70":"31.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037002"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"19000","Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA037002":"AB_10672383"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Tissue RNA - adipose tissue [nTPM]":"8.5","Tissue RNA - adrenal gland [nTPM]":"3.6","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"35.1","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"6.2","Tissue RNA - breast [nTPM]":"2.2","Tissue RNA - cerebellum [nTPM]":"1.5","Tissue RNA - cerebral cortex [nTPM]":"0.9","Tissue RNA - cervix [nTPM]":"2.3","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"2.8","Tissue RNA - duodenum [nTPM]":"2.4","Tissue RNA - endometrium 1 [nTPM]":"0.8","Tissue RNA - epididymis [nTPM]":"3.2","Tissue RNA - esophagus [nTPM]":"0.8","Tissue RNA - fallopian tube [nTPM]":"2.3","Tissue RNA - gallbladder [nTPM]":"3.0","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"0.5","Tissue RNA - hypothalamus [nTPM]":"0.7","Tissue RNA - kidney [nTPM]":"3.2","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"8.1","Tissue RNA - lymph node [nTPM]":"82.2","Tissue RNA - medulla oblongata [nTPM]":"0.8","Tissue RNA - midbrain [nTPM]":"0.8","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"0.8","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"5.8","Tissue RNA - rectum [nTPM]":"3.3","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"2.4","Tissue RNA - seminal vesicle [nTPM]":"4.7","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"24.2","Tissue RNA - smooth muscle [nTPM]":"1.0","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"56.1","Tissue RNA - stomach 1 [nTPM]":"7.4","Tissue RNA - testis [nTPM]":"3.0","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"9.7","Tissue RNA - thyroid gland [nTPM]":"12.9","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"96.4","Tissue RNA - urinary bladder [nTPM]":"7.6","Tissue RNA - vagina [nTPM]":"0.7","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"3.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"3.4","Cell RNA - ASC TERT1 [nTPM]":"1.4","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.6","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"4.6","Cell RNA - Daudi [nTPM]":"13.6","Cell RNA - EFO-21 [nTPM]":"1.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"1.5","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"10.6","Cell RNA - HeLa [nTPM]":"2.6","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"9.6","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.6","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"4.0","Cell RNA - LHCN-M2 [nTPM]":"0.6","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.4","Cell RNA - PC-3 [nTPM]":"5.7","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.6","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.4","Cell RNA - RT4 [nTPM]":"6.1","Cell RNA - SCLC-21H [nTPM]":"2.6","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.5","Cell RNA - THP-1 [nTPM]":"2.5","Cell RNA - TIME [nTPM]":"1.3","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"31.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"2.2","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"5.3","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"10.8","Blood RNA - classical monocyte [nTPM]":"1.7","Blood RNA - eosinophil [nTPM]":"19.7","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"310.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"10.5","Blood RNA - naive B-cell [nTPM]":"253.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.9","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"5.2","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"11.3","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"1.5","Brain RNA - cerebral cortex [nTPM]":"0.9","Brain RNA - hippocampal formation [nTPM]":"0.5","Brain RNA - hypothalamus [nTPM]":"0.7","Brain RNA - medulla oblongata [nTPM]":"0.8","Brain RNA - midbrain [nTPM]":"0.8","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"3.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.1","Single Cell Type RNA - Astrocytes [nTPM]":"6.8","Single Cell Type RNA - B-cells [nTPM]":"455.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"10.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.1","Single Cell Type RNA - dendritic cells [nTPM]":"5.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"2.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"6.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.6","Single Cell Type RNA - Fibroblasts [nTPM]":"1.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.2","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.9","Single Cell Type RNA - Langerhans cells [nTPM]":"25.1","Single Cell Type RNA - Late spermatids [nTPM]":"2.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"13.0","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"2.8","Single Cell Type RNA - Muller glia cells [nTPM]":"1.8","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.1","Single Cell Type RNA - Paneth cells [nTPM]":"1.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"13.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.8","Single Cell Type RNA - Spermatocytes [nTPM]":"1.9","Single Cell Type RNA - Spermatogonia [nTPM]":"5.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"12.9","Single Cell Type RNA - Theca cells [nTPM]":"2.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.1","Single Cell Type RNA - Urothelial cells [nTPM]":"4.3"},{"Gene":"C1QA","Gene synonym":[],"Ensembl":"ENSG00000173372","Gene description":"Complement C1q A chain","Uniprot":["P02745"],"Chromosome":"1","Position":"22636628-22639678","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":["Complement pathway","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"1092.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"Hofbauer cells":"1663.2","Kupffer cells":"5007.4","Macrophages":"1874.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"39","RNA blood cell specific nTPM":{"intermediate monocyte":"226.1","non-classical monocyte":"181.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"60","RNA blood lineage specific nTPM":{"monocytes":"226.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"2.3","NB-4":"1.4","RPMI-8226":"7.1","SCLC-21H":"3.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002350","CAB009823"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2700000000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB009823":"AB_2228238","HPA002350":"AB_1078552"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.58e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Tissue RNA - adipose tissue [nTPM]":"375.1","Tissue RNA - adrenal gland [nTPM]":"235.6","Tissue RNA - amygdala [nTPM]":"86.6","Tissue RNA - appendix [nTPM]":"134.0","Tissue RNA - basal ganglia [nTPM]":"85.6","Tissue RNA - bone marrow [nTPM]":"53.9","Tissue RNA - breast [nTPM]":"95.9","Tissue RNA - cerebellum [nTPM]":"85.8","Tissue RNA - cerebral cortex [nTPM]":"135.3","Tissue RNA - cervix [nTPM]":"75.8","Tissue RNA - choroid plexus [nTPM]":"120.0","Tissue RNA - colon [nTPM]":"142.8","Tissue RNA - duodenum [nTPM]":"172.3","Tissue RNA - endometrium 1 [nTPM]":"43.1","Tissue RNA - epididymis [nTPM]":"26.0","Tissue RNA - esophagus [nTPM]":"58.3","Tissue RNA - fallopian tube [nTPM]":"75.6","Tissue RNA - gallbladder [nTPM]":"172.4","Tissue RNA - heart muscle [nTPM]":"74.8","Tissue RNA - hippocampal formation [nTPM]":"82.9","Tissue RNA - hypothalamus [nTPM]":"93.7","Tissue RNA - kidney [nTPM]":"56.2","Tissue RNA - liver [nTPM]":"208.8","Tissue RNA - lung [nTPM]":"404.3","Tissue RNA - lymph node [nTPM]":"532.3","Tissue RNA - medulla oblongata [nTPM]":"126.7","Tissue RNA - midbrain [nTPM]":"110.1","Tissue RNA - ovary [nTPM]":"37.5","Tissue RNA - pancreas [nTPM]":"34.3","Tissue RNA - parathyroid gland [nTPM]":"26.2","Tissue RNA - pituitary gland [nTPM]":"46.3","Tissue RNA - placenta [nTPM]":"256.3","Tissue RNA - pons [nTPM]":"110.3","Tissue RNA - prostate [nTPM]":"47.1","Tissue RNA - rectum [nTPM]":"120.2","Tissue RNA - retina [nTPM]":"4.1","Tissue RNA - salivary gland [nTPM]":"48.1","Tissue RNA - seminal vesicle [nTPM]":"54.6","Tissue RNA - skeletal muscle [nTPM]":"14.8","Tissue RNA - skin 1 [nTPM]":"21.8","Tissue RNA - small intestine [nTPM]":"190.1","Tissue RNA - smooth muscle [nTPM]":"195.0","Tissue RNA - spinal cord [nTPM]":"107.5","Tissue RNA - spleen [nTPM]":"1092.6","Tissue RNA - stomach 1 [nTPM]":"90.8","Tissue RNA - testis [nTPM]":"38.2","Tissue RNA - thalamus [nTPM]":"109.4","Tissue RNA - thymus [nTPM]":"100.3","Tissue RNA - thyroid gland [nTPM]":"36.5","Tissue RNA - tongue [nTPM]":"49.3","Tissue RNA - tonsil [nTPM]":"68.0","Tissue RNA - urinary bladder [nTPM]":"257.5","Tissue RNA - vagina [nTPM]":"30.4","Tissue RNA - white matter [nTPM]":"131.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.8","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"2.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"1.4","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.5","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"7.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"3.0","Cell RNA - SH-SY5Y [nTPM]":"0.9","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.5","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.8","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"5.2","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"226.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"3.7","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"181.7","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"9.7","Brain RNA - amygdala [nTPM]":"86.6","Brain RNA - basal ganglia [nTPM]":"85.6","Brain RNA - cerebellum [nTPM]":"85.8","Brain RNA - cerebral cortex [nTPM]":"135.3","Brain RNA - hippocampal formation [nTPM]":"82.9","Brain RNA - hypothalamus [nTPM]":"93.7","Brain RNA - medulla oblongata [nTPM]":"126.7","Brain RNA - midbrain [nTPM]":"110.1","Brain RNA - pons [nTPM]":"110.3","Brain RNA - spinal cord [nTPM]":"107.5","Brain RNA - thalamus [nTPM]":"109.4","Brain RNA - white matter [nTPM]":"131.6","Single Cell Type RNA - Adipocytes [nTPM]":"17.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"55.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"19.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"37.1","Single Cell Type RNA - Club cells [nTPM]":"18.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.7","Single Cell Type RNA - dendritic cells [nTPM]":"2.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"4.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"46.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"41.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.3","Single Cell Type RNA - Fibroblasts [nTPM]":"9.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"21.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"76.1","Single Cell Type RNA - Hepatocytes [nTPM]":"26.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"1663.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"5007.4","Single Cell Type RNA - Langerhans cells [nTPM]":"291.4","Single Cell Type RNA - Late spermatids [nTPM]":"9.9","Single Cell Type RNA - Leydig cells [nTPM]":"13.1","Single Cell Type RNA - Macrophages [nTPM]":"1874.2","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"16.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"2.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"78.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"2.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.2","Single Cell Type RNA - T-cells [nTPM]":"11.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"CARD14","Gene synonym":["BIMP2","CARMA2","PSORS2"],"Ensembl":"ENSG00000141527","Gene description":"Caspase recruitment domain family member 14","Uniprot":["Q9BXL6"],"Chromosome":"17","Position":"80169992-80209331","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"13.5","skin 1":"14.4","vagina":"7.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"8.2","Microglial cells":"6.5","Oligodendrocytes":"11.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"5.2","SK-BR-3":"6.9","T-47d":"10.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023388"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Aggresome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 35: Glandular cells - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":["Aggresome"],"Antibody RRID":{"HPA023388":"AB_1846020"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"1.1","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"2.6","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"4.9","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"1.1","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"13.5","Tissue RNA - fallopian tube [nTPM]":"0.6","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"0.6","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"2.5","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"3.3","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"14.4","Tissue RNA - small intestine [nTPM]":"0.8","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"1.5","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"1.6","Tissue RNA - urinary bladder [nTPM]":"1.0","Tissue RNA - vagina [nTPM]":"7.3","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"1.7","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.9","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.8","Cell RNA - HEK 293 [nTPM]":"0.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"1.9","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.9","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"5.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"1.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"1.1","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"1.6","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"6.9","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"10.4","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"2.2","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"2.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"0.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"8.2","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"1.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.5","Single Cell Type RNA - Urothelial cells [nTPM]":"3.6"},{"Gene":"CCL5","Gene synonym":["D17S136E","MGC17164","RANTES","SCYA5","SISd","TCP228"],"Ensembl":"ENSG00000271503","Gene description":"C-C motif chemokine ligand 5","Uniprot":["P13501"],"Chromosome":"17","Position":"35871491-35880793","Protein class":["Cancer-related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Chemotaxis","Inflammatory response"],"Molecular function":["Cytokine"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"122.1","lymphoid tissue":"135.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"dendritic cells":"2049.9","NK-cells":"2344.0","T-cells":"1947.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"6788.6","memory CD8 T-cell":"7164.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"NK-cells":"2041.1","T-cells":"7164.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HL-60":"94.1","NB-4":"539.9","THP-1":"139.9","U-937":"120.1"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB078447"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":20100000,"Blood concentration - Conc. blood MS [pg\/L]":"2900000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB078447":"AB_223462"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.34e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.37e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.42e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.61e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Tissue RNA - adipose tissue [nTPM]":"17.2","Tissue RNA - adrenal gland [nTPM]":"17.1","Tissue RNA - amygdala [nTPM]":"3.9","Tissue RNA - appendix [nTPM]":"36.3","Tissue RNA - basal ganglia [nTPM]":"4.0","Tissue RNA - bone marrow [nTPM]":"122.1","Tissue RNA - breast [nTPM]":"19.5","Tissue RNA - cerebellum [nTPM]":"3.8","Tissue RNA - cerebral cortex [nTPM]":"6.5","Tissue RNA - cervix [nTPM]":"15.5","Tissue RNA - choroid plexus [nTPM]":"5.4","Tissue RNA - colon [nTPM]":"27.7","Tissue RNA - duodenum [nTPM]":"48.7","Tissue RNA - endometrium 1 [nTPM]":"15.7","Tissue RNA - epididymis [nTPM]":"14.4","Tissue RNA - esophagus [nTPM]":"15.8","Tissue RNA - fallopian tube [nTPM]":"14.0","Tissue RNA - gallbladder [nTPM]":"42.9","Tissue RNA - heart muscle [nTPM]":"8.9","Tissue RNA - hippocampal formation [nTPM]":"3.9","Tissue RNA - hypothalamus [nTPM]":"3.7","Tissue RNA - kidney [nTPM]":"7.5","Tissue RNA - liver [nTPM]":"28.4","Tissue RNA - lung [nTPM]":"57.4","Tissue RNA - lymph node [nTPM]":"135.2","Tissue RNA - medulla oblongata [nTPM]":"7.3","Tissue RNA - midbrain [nTPM]":"4.3","Tissue RNA - ovary [nTPM]":"16.9","Tissue RNA - pancreas [nTPM]":"7.0","Tissue RNA - parathyroid gland [nTPM]":"3.0","Tissue RNA - pituitary gland [nTPM]":"3.8","Tissue RNA - placenta [nTPM]":"6.3","Tissue RNA - pons [nTPM]":"6.4","Tissue RNA - prostate [nTPM]":"10.4","Tissue RNA - rectum [nTPM]":"25.6","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"33.5","Tissue RNA - seminal vesicle [nTPM]":"7.9","Tissue RNA - skeletal muscle [nTPM]":"4.8","Tissue RNA - skin 1 [nTPM]":"4.0","Tissue RNA - small intestine [nTPM]":"84.5","Tissue RNA - smooth muscle [nTPM]":"10.5","Tissue RNA - spinal cord [nTPM]":"5.8","Tissue RNA - spleen [nTPM]":"123.9","Tissue RNA - stomach 1 [nTPM]":"47.9","Tissue RNA - testis [nTPM]":"4.6","Tissue RNA - thalamus [nTPM]":"4.7","Tissue RNA - thymus [nTPM]":"29.5","Tissue RNA - thyroid gland [nTPM]":"11.5","Tissue RNA - tongue [nTPM]":"2.7","Tissue RNA - tonsil [nTPM]":"33.4","Tissue RNA - urinary bladder [nTPM]":"31.4","Tissue RNA - vagina [nTPM]":"9.5","Tissue RNA - white matter [nTPM]":"6.1","Cell RNA - A-431 [nTPM]":"0.7","Cell RNA - A549 [nTPM]":"0.5","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.5","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"0.8","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"4.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.8","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"1.7","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"1.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.9","Cell RNA - GAMG [nTPM]":"1.3","Cell RNA - HaCaT [nTPM]":"0.9","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"2.3","Cell RNA - HDLM-2 [nTPM]":"6.5","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"1.5","Cell RNA - Hep G2 [nTPM]":"0.6","Cell RNA - HHSteC [nTPM]":"0.5","Cell RNA - HL-60 [nTPM]":"94.1","Cell RNA - HMC-1 [nTPM]":"0.8","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.5","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"12.5","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.6","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"539.9","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.6","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"14.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"1.2","Cell RNA - SK-MEL-30 [nTPM]":"13.4","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"139.9","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.6","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.6","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"14.2","Cell RNA - U-266\/84 [nTPM]":"6.6","Cell RNA - U-698 [nTPM]":"0.8","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"120.1","Cell RNA - WM-115 [nTPM]":"1.3","Blood RNA - basophil [nTPM]":"657.8","Blood RNA - classical monocyte [nTPM]":"30.0","Blood RNA - eosinophil [nTPM]":"35.8","Blood RNA - gdT-cell [nTPM]":"6788.6","Blood RNA - intermediate monocyte [nTPM]":"21.3","Blood RNA - MAIT T-cell [nTPM]":"4221.0","Blood RNA - memory B-cell [nTPM]":"61.3","Blood RNA - memory CD4 T-cell [nTPM]":"1394.5","Blood RNA - memory CD8 T-cell [nTPM]":"7164.3","Blood RNA - myeloid DC [nTPM]":"49.8","Blood RNA - naive B-cell [nTPM]":"41.6","Blood RNA - naive CD4 T-cell [nTPM]":"332.4","Blood RNA - naive CD8 T-cell [nTPM]":"4032.4","Blood RNA - neutrophil [nTPM]":"189.9","Blood RNA - NK-cell [nTPM]":"2041.1","Blood RNA - non-classical monocyte [nTPM]":"26.1","Blood RNA - plasmacytoid DC [nTPM]":"46.5","Blood RNA - T-reg [nTPM]":"25.9","Blood RNA - total PBMC [nTPM]":"6664.4","Brain RNA - amygdala [nTPM]":"3.9","Brain RNA - basal ganglia [nTPM]":"4.0","Brain RNA - cerebellum [nTPM]":"3.8","Brain RNA - cerebral cortex [nTPM]":"6.5","Brain RNA - hippocampal formation [nTPM]":"3.9","Brain RNA - hypothalamus [nTPM]":"3.7","Brain RNA - medulla oblongata [nTPM]":"7.3","Brain RNA - midbrain [nTPM]":"4.3","Brain RNA - pons [nTPM]":"6.4","Brain RNA - spinal cord [nTPM]":"5.8","Brain RNA - thalamus [nTPM]":"4.7","Brain RNA - white matter [nTPM]":"6.1","Single Cell Type RNA - Adipocytes [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"99.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"244.4","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"55.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"41.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.8","Single Cell Type RNA - dendritic cells [nTPM]":"2049.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.4","Single Cell Type RNA - Endothelial cells [nTPM]":"24.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"106.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.1","Single Cell Type RNA - Fibroblasts [nTPM]":"26.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"46.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.7","Single Cell Type RNA - granulocytes [nTPM]":"80.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"45.0","Single Cell Type RNA - Hepatocytes [nTPM]":"7.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"33.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"48.0","Single Cell Type RNA - Langerhans cells [nTPM]":"25.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"256.3","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"38.5","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"2344.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.6","Single Cell Type RNA - Paneth cells [nTPM]":"6.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"179.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"28.2","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.0","Single Cell Type RNA - T-cells [nTPM]":"1947.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.5","Single Cell Type RNA - Urothelial cells [nTPM]":"1.9"},{"Gene":"CCR6","Gene synonym":["BN-1","CD196","CKR-L3","CMKBR6","DCR2","DRY-6","GPR-CY4","GPR29","STRL22"],"Ensembl":"ENSG00000112486","Gene description":"C-C motif chemokine receptor 6","Uniprot":["P51684"],"Chromosome":"6","Position":"167111807-167139696","Protein class":["CD markers","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"lymphoid tissue":"35.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"B-cells":"44.0","Late spermatids":"26.4","T-cells":"40.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"77.4","T-cells":"74.5"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Hep G2":"9.4","OE19":"3.2"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"7","RNA mouse brain regional specific nTPM":{"basal ganglia":"1.8"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB006820","HPA014488"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB006820":null,"HPA014488":"AB_1846639"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.98e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"11.4","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"2.5","Tissue RNA - breast [nTPM]":"2.2","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"0.9","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"1.9","Tissue RNA - duodenum [nTPM]":"2.8","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"1.4","Tissue RNA - fallopian tube [nTPM]":"0.6","Tissue RNA - gallbladder [nTPM]":"2.1","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.6","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"0.5","Tissue RNA - liver [nTPM]":"0.6","Tissue RNA - lung [nTPM]":"1.2","Tissue RNA - lymph node [nTPM]":"18.1","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"1.0","Tissue RNA - rectum [nTPM]":"2.2","Tissue RNA - retina [nTPM]":"1.4","Tissue RNA - salivary gland [nTPM]":"0.6","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"2.4","Tissue RNA - small intestine [nTPM]":"6.6","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"12.5","Tissue RNA - stomach 1 [nTPM]":"3.6","Tissue RNA - testis [nTPM]":"2.7","Tissue RNA - thalamus [nTPM]":"0.5","Tissue RNA - thymus [nTPM]":"3.6","Tissue RNA - thyroid gland [nTPM]":"0.6","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"35.8","Tissue RNA - urinary bladder [nTPM]":"4.4","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.8","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.9","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"9.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"3.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"4.5","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"74.5","Blood RNA - memory B-cell [nTPM]":"69.0","Blood RNA - memory CD4 T-cell [nTPM]":"30.7","Blood RNA - memory CD8 T-cell [nTPM]":"11.6","Blood RNA - myeloid DC [nTPM]":"17.5","Blood RNA - naive B-cell [nTPM]":"77.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"58.7","Blood RNA - total PBMC [nTPM]":"6.9","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"0.6","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.5","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.2","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"44.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"3.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"8.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"7.3","Single Cell Type RNA - Late spermatids [nTPM]":"26.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"5.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"3.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"5.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"2.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"40.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.8","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"CD151","Gene synonym":["PETA-3","RAPH","SFA-1","TSPAN24"],"Ensembl":"ENSG00000177697","Gene description":"CD151 molecule (Raph blood group)","Uniprot":["P48509"],"Chromosome":"11","Position":"832887-839831","Protein class":["Blood group antigen proteins","CD markers","Disease related genes","Human disease related genes","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Host-virus interaction"],"Molecular function":["Blood group antigen"],"Disease involvement":["Deafness","Epidermolysis bullosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"716.2","Exocrine glandular cells":"636.7","Pancreatic endocrine cells":"736.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002428","HPA011906"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 1: Pancreatic cells - Digestion","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002428":"AB_564129","HPA011906":"AB_1846245"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.58e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.46e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.92e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Tissue RNA - adipose tissue [nTPM]":"332.4","Tissue RNA - adrenal gland [nTPM]":"159.5","Tissue RNA - amygdala [nTPM]":"54.0","Tissue RNA - appendix [nTPM]":"79.7","Tissue RNA - basal ganglia [nTPM]":"53.5","Tissue RNA - bone marrow [nTPM]":"25.0","Tissue RNA - breast [nTPM]":"277.8","Tissue RNA - cerebellum [nTPM]":"52.5","Tissue RNA - cerebral cortex [nTPM]":"67.6","Tissue RNA - cervix [nTPM]":"181.6","Tissue RNA - choroid plexus [nTPM]":"66.1","Tissue RNA - colon [nTPM]":"219.7","Tissue RNA - duodenum [nTPM]":"140.6","Tissue RNA - endometrium 1 [nTPM]":"264.6","Tissue RNA - epididymis [nTPM]":"103.0","Tissue RNA - esophagus [nTPM]":"97.5","Tissue RNA - fallopian tube [nTPM]":"184.3","Tissue RNA - gallbladder [nTPM]":"132.4","Tissue RNA - heart muscle [nTPM]":"345.8","Tissue RNA - hippocampal formation [nTPM]":"54.2","Tissue RNA - hypothalamus [nTPM]":"65.3","Tissue RNA - kidney [nTPM]":"194.3","Tissue RNA - liver [nTPM]":"145.3","Tissue RNA - lung [nTPM]":"240.1","Tissue RNA - lymph node [nTPM]":"35.4","Tissue RNA - medulla oblongata [nTPM]":"64.5","Tissue RNA - midbrain [nTPM]":"57.4","Tissue RNA - ovary [nTPM]":"116.2","Tissue RNA - pancreas [nTPM]":"278.3","Tissue RNA - parathyroid gland [nTPM]":"85.9","Tissue RNA - pituitary gland [nTPM]":"81.1","Tissue RNA - placenta [nTPM]":"110.1","Tissue RNA - pons [nTPM]":"60.5","Tissue RNA - prostate [nTPM]":"182.9","Tissue RNA - rectum [nTPM]":"99.8","Tissue RNA - retina [nTPM]":"9.6","Tissue RNA - salivary gland [nTPM]":"243.5","Tissue RNA - seminal vesicle [nTPM]":"194.2","Tissue RNA - skeletal muscle [nTPM]":"113.1","Tissue RNA - skin 1 [nTPM]":"107.0","Tissue RNA - small intestine [nTPM]":"149.4","Tissue RNA - smooth muscle [nTPM]":"255.2","Tissue RNA - spinal cord [nTPM]":"58.3","Tissue RNA - spleen [nTPM]":"94.8","Tissue RNA - stomach 1 [nTPM]":"187.3","Tissue RNA - testis [nTPM]":"44.8","Tissue RNA - thalamus [nTPM]":"58.6","Tissue RNA - thymus [nTPM]":"15.0","Tissue RNA - thyroid gland [nTPM]":"133.5","Tissue RNA - tongue [nTPM]":"77.0","Tissue RNA - tonsil [nTPM]":"30.6","Tissue RNA - urinary bladder [nTPM]":"203.1","Tissue RNA - vagina [nTPM]":"151.3","Tissue RNA - white matter [nTPM]":"58.0","Cell RNA - A-431 [nTPM]":"380.0","Cell RNA - A549 [nTPM]":"475.3","Cell RNA - AF22 [nTPM]":"71.8","Cell RNA - AN3-CA [nTPM]":"256.3","Cell RNA - ASC diff [nTPM]":"1088.7","Cell RNA - ASC TERT1 [nTPM]":"422.8","Cell RNA - BEWO [nTPM]":"110.4","Cell RNA - BJ [nTPM]":"587.1","Cell RNA - BJ hTERT+ [nTPM]":"400.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"285.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"241.2","Cell RNA - CACO-2 [nTPM]":"252.6","Cell RNA - CAPAN-2 [nTPM]":"677.2","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"224.0","Cell RNA - fHDF\/TERT166 [nTPM]":"943.5","Cell RNA - GAMG [nTPM]":"388.4","Cell RNA - HaCaT [nTPM]":"358.4","Cell RNA - HAP1 [nTPM]":"71.1","Cell RNA - HBEC3-KT [nTPM]":"498.4","Cell RNA - HBF TERT88 [nTPM]":"96.1","Cell RNA - HDLM-2 [nTPM]":"135.0","Cell RNA - HEK 293 [nTPM]":"236.6","Cell RNA - HEL [nTPM]":"112.8","Cell RNA - HeLa [nTPM]":"139.1","Cell RNA - Hep G2 [nTPM]":"193.4","Cell RNA - HHSteC [nTPM]":"366.7","Cell RNA - HL-60 [nTPM]":"90.2","Cell RNA - HMC-1 [nTPM]":"157.4","Cell RNA - HSkMC [nTPM]":"388.6","Cell RNA - hTCEpi [nTPM]":"328.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"164.5","Cell RNA - hTERT-HME1 [nTPM]":"367.8","Cell RNA - hTERT-RPE1 [nTPM]":"1089.2","Cell RNA - HUVEC TERT2 [nTPM]":"348.8","Cell RNA - JURKAT [nTPM]":"16.4","Cell RNA - K-562 [nTPM]":"135.1","Cell RNA - Karpas-707 [nTPM]":"56.3","Cell RNA - LHCN-M2 [nTPM]":"485.9","Cell RNA - MCF7 [nTPM]":"196.1","Cell RNA - MOLT-4 [nTPM]":"1.9","Cell RNA - NB-4 [nTPM]":"99.5","Cell RNA - NTERA-2 [nTPM]":"48.0","Cell RNA - OE19 [nTPM]":"232.9","Cell RNA - PC-3 [nTPM]":"569.4","Cell RNA - REH [nTPM]":"20.0","Cell RNA - RH-30 [nTPM]":"173.7","Cell RNA - RPMI-8226 [nTPM]":"106.4","Cell RNA - RPTEC TERT1 [nTPM]":"642.8","Cell RNA - RT4 [nTPM]":"102.1","Cell RNA - SCLC-21H [nTPM]":"99.5","Cell RNA - SH-SY5Y [nTPM]":"111.8","Cell RNA - SiHa [nTPM]":"578.9","Cell RNA - SK-BR-3 [nTPM]":"371.5","Cell RNA - SK-MEL-30 [nTPM]":"121.5","Cell RNA - SuSa [nTPM]":"81.6","Cell RNA - T-47d [nTPM]":"145.8","Cell RNA - THP-1 [nTPM]":"102.4","Cell RNA - TIME [nTPM]":"600.0","Cell RNA - U-138 MG [nTPM]":"462.6","Cell RNA - U-2 OS [nTPM]":"209.3","Cell RNA - U-2197 [nTPM]":"147.5","Cell RNA - U-251 MG [nTPM]":"352.9","Cell RNA - U-266\/70 [nTPM]":"62.0","Cell RNA - U-266\/84 [nTPM]":"66.5","Cell RNA - U-698 [nTPM]":"4.5","Cell RNA - U-87 MG [nTPM]":"437.5","Cell RNA - U-937 [nTPM]":"89.7","Cell RNA - WM-115 [nTPM]":"265.8","Blood RNA - basophil [nTPM]":"24.6","Blood RNA - classical monocyte [nTPM]":"19.1","Blood RNA - eosinophil [nTPM]":"15.2","Blood RNA - gdT-cell [nTPM]":"5.7","Blood RNA - intermediate monocyte [nTPM]":"19.3","Blood RNA - MAIT T-cell [nTPM]":"6.8","Blood RNA - memory B-cell [nTPM]":"3.0","Blood RNA - memory CD4 T-cell [nTPM]":"4.7","Blood RNA - memory CD8 T-cell [nTPM]":"5.0","Blood RNA - myeloid DC [nTPM]":"11.9","Blood RNA - naive B-cell [nTPM]":"2.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"3.0","Blood RNA - neutrophil [nTPM]":"7.3","Blood RNA - NK-cell [nTPM]":"8.2","Blood RNA - non-classical monocyte [nTPM]":"24.1","Blood RNA - plasmacytoid DC [nTPM]":"1.8","Blood RNA - T-reg [nTPM]":"2.9","Blood RNA - total PBMC [nTPM]":"10.8","Brain RNA - amygdala [nTPM]":"54.0","Brain RNA - basal ganglia [nTPM]":"53.5","Brain RNA - cerebellum [nTPM]":"52.5","Brain RNA - cerebral cortex [nTPM]":"67.6","Brain RNA - hippocampal formation [nTPM]":"54.2","Brain RNA - hypothalamus [nTPM]":"65.3","Brain RNA - medulla oblongata [nTPM]":"64.5","Brain RNA - midbrain [nTPM]":"57.4","Brain RNA - pons [nTPM]":"60.5","Brain RNA - spinal cord [nTPM]":"58.3","Brain RNA - thalamus [nTPM]":"58.6","Brain RNA - white matter [nTPM]":"58.0","Single Cell Type RNA - Adipocytes [nTPM]":"294.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"208.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"79.1","Single Cell Type RNA - Astrocytes [nTPM]":"13.1","Single Cell Type RNA - B-cells [nTPM]":"12.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"70.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"143.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"328.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"60.9","Single Cell Type RNA - Bipolar cells [nTPM]":"16.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"180.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"203.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"180.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"133.0","Single Cell Type RNA - Club cells [nTPM]":"159.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"248.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"222.6","Single Cell Type RNA - dendritic cells [nTPM]":"15.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"542.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"716.2","Single Cell Type RNA - Early spermatids [nTPM]":"2.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"60.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"114.6","Single Cell Type RNA - Endothelial cells [nTPM]":"214.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"127.6","Single Cell Type RNA - Erythroid cells [nTPM]":"28.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"636.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"423.8","Single Cell Type RNA - Fibroblasts [nTPM]":"173.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"236.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"143.7","Single Cell Type RNA - granulocytes [nTPM]":"81.3","Single Cell Type RNA - Granulosa cells [nTPM]":"103.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"265.2","Single Cell Type RNA - Hepatocytes [nTPM]":"54.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"130.0","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"388.5","Single Cell Type RNA - Ionocytes [nTPM]":"138.4","Single Cell Type RNA - Kupffer cells [nTPM]":"59.3","Single Cell Type RNA - Langerhans cells [nTPM]":"70.4","Single Cell Type RNA - Late spermatids [nTPM]":"11.3","Single Cell Type RNA - Leydig cells [nTPM]":"123.6","Single Cell Type RNA - Macrophages [nTPM]":"81.8","Single Cell Type RNA - Melanocytes [nTPM]":"128.1","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"75.6","Single Cell Type RNA - Muller glia cells [nTPM]":"94.8","Single Cell Type RNA - NK-cells [nTPM]":"23.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"736.6","Single Cell Type RNA - Paneth cells [nTPM]":"477.9","Single Cell Type RNA - Peritubular cells [nTPM]":"283.2","Single Cell Type RNA - Plasma cells [nTPM]":"26.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"307.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"440.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"124.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"52.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.0","Single Cell Type RNA - Sertoli cells [nTPM]":"210.4","Single Cell Type RNA - Skeletal myocytes [nTPM]":"96.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"310.3","Single Cell Type RNA - Spermatocytes [nTPM]":"5.6","Single Cell Type RNA - Spermatogonia [nTPM]":"13.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"73.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"54.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"185.7","Single Cell Type RNA - T-cells [nTPM]":"29.7","Single Cell Type RNA - Theca cells [nTPM]":"61.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"289.8","Single Cell Type RNA - Urothelial cells [nTPM]":"199.6"},{"Gene":"CD247","Gene synonym":["CD3H","CD3Q","CD3Z"],"Ensembl":"ENSG00000198821","Gene description":"CD247 molecule","Uniprot":["P20963"],"Chromosome":"1","Position":"167430640-167518610","Protein class":["CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity"],"Molecular function":["Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"bone marrow":"49.0","lymphoid tissue":"179.4"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"9","RNA single cell type specific nTPM":{"dendritic cells":"492.1","NK-cells":"727.1","T-cells":"247.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"25","RNA blood cell specific nTPM":{"gdT-cell":"376.4","MAIT T-cell":"208.9","memory CD4 T-cell":"190.0","memory CD8 T-cell":"219.7","naive CD4 T-cell":"237.8","naive CD8 T-cell":"195.1","NK-cell":"225.3","T-reg":"254.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"32","RNA blood lineage specific nTPM":{"NK-cells":"225.3","T-cells":"376.4"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"25","RNA cell line specific nTPM":{"HDLM-2":"155.9","JURKAT":"113.1","MOLT-4":"167.1"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004651","HPA008750"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB004651":"AB_425347","HPA008750":"AB_1857863"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.12e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.63e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.98e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.94e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-3"},"Tissue RNA - adipose tissue [nTPM]":"3.2","Tissue RNA - adrenal gland [nTPM]":"1.7","Tissue RNA - amygdala [nTPM]":"2.3","Tissue RNA - appendix [nTPM]":"25.3","Tissue RNA - basal ganglia [nTPM]":"2.3","Tissue RNA - bone marrow [nTPM]":"49.0","Tissue RNA - breast [nTPM]":"1.9","Tissue RNA - cerebellum [nTPM]":"2.2","Tissue RNA - cerebral cortex [nTPM]":"2.5","Tissue RNA - cervix [nTPM]":"1.9","Tissue RNA - choroid plexus [nTPM]":"1.9","Tissue RNA - colon [nTPM]":"4.3","Tissue RNA - duodenum [nTPM]":"7.1","Tissue RNA - endometrium 1 [nTPM]":"2.3","Tissue RNA - epididymis [nTPM]":"3.1","Tissue RNA - esophagus [nTPM]":"2.1","Tissue RNA - fallopian tube [nTPM]":"1.8","Tissue RNA - gallbladder [nTPM]":"5.5","Tissue RNA - heart muscle [nTPM]":"1.3","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"2.3","Tissue RNA - kidney [nTPM]":"2.0","Tissue RNA - liver [nTPM]":"5.4","Tissue RNA - lung [nTPM]":"10.9","Tissue RNA - lymph node [nTPM]":"57.7","Tissue RNA - medulla oblongata [nTPM]":"2.3","Tissue RNA - midbrain [nTPM]":"2.2","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":"0.8","Tissue RNA - placenta [nTPM]":"1.4","Tissue RNA - pons [nTPM]":"2.2","Tissue RNA - prostate [nTPM]":"1.8","Tissue RNA - rectum [nTPM]":"4.6","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"2.4","Tissue RNA - seminal vesicle [nTPM]":"1.6","Tissue RNA - skeletal muscle [nTPM]":"1.4","Tissue RNA - skin 1 [nTPM]":"1.1","Tissue RNA - small intestine [nTPM]":"14.3","Tissue RNA - smooth muscle [nTPM]":"1.5","Tissue RNA - spinal cord [nTPM]":"2.1","Tissue RNA - spleen [nTPM]":"40.2","Tissue RNA - stomach 1 [nTPM]":"7.0","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"2.9","Tissue RNA - thymus [nTPM]":"179.4","Tissue RNA - thyroid gland [nTPM]":"2.5","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"36.4","Tissue RNA - urinary bladder [nTPM]":"7.3","Tissue RNA - vagina [nTPM]":"1.9","Tissue RNA - white matter [nTPM]":"2.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"5.7","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"155.9","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.8","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"113.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"167.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.8","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"8.3","Blood RNA - classical monocyte [nTPM]":"1.0","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"376.4","Blood RNA - intermediate monocyte [nTPM]":"1.4","Blood RNA - MAIT T-cell [nTPM]":"208.9","Blood RNA - memory B-cell [nTPM]":"9.3","Blood RNA - memory CD4 T-cell [nTPM]":"190.0","Blood RNA - memory CD8 T-cell [nTPM]":"219.7","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"4.9","Blood RNA - naive CD4 T-cell [nTPM]":"237.8","Blood RNA - naive CD8 T-cell [nTPM]":"195.1","Blood RNA - neutrophil [nTPM]":"8.7","Blood RNA - NK-cell [nTPM]":"225.3","Blood RNA - non-classical monocyte [nTPM]":"1.2","Blood RNA - plasmacytoid DC [nTPM]":"2.8","Blood RNA - T-reg [nTPM]":"254.5","Blood RNA - total PBMC [nTPM]":"231.2","Brain RNA - amygdala [nTPM]":"2.3","Brain RNA - basal ganglia [nTPM]":"2.3","Brain RNA - cerebellum [nTPM]":"2.2","Brain RNA - cerebral cortex [nTPM]":"2.5","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"2.3","Brain RNA - medulla oblongata [nTPM]":"2.3","Brain RNA - midbrain [nTPM]":"2.2","Brain RNA - pons [nTPM]":"2.2","Brain RNA - spinal cord [nTPM]":"2.1","Brain RNA - thalamus [nTPM]":"2.9","Brain RNA - white matter [nTPM]":"2.5","Single Cell Type RNA - Adipocytes [nTPM]":"3.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.0","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"8.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"492.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.8","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"14.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"2.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.1","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.1","Single Cell Type RNA - Hepatocytes [nTPM]":"1.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"7.8","Single Cell Type RNA - Langerhans cells [nTPM]":"1.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"5.9","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"7.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"727.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"51.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"2.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"247.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"CDSN","Gene synonym":["D6S586E"],"Ensembl":"ENSG00000204539","Gene description":"Corneodesmosin","Uniprot":[],"Chromosome":"6","Position":"31115087-31120446","Protein class":["Human disease related genes","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"104","RNA tissue specific nTPM":{"skin 1":"696.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"2.6","Gastric mucus-secreting cells":"2.0","Glandular and luminal cells":"7.1","granulocytes":"4.5","Suprabasal keratinocytes":"5.3"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"8","RNA cancer specific FPKM":{"head and neck cancer":"2.4","melanoma":"2.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"A-431":"1.6"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebral cortex":"1.5"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044730","HPA054184"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA044730":"AB_10964923","HPA054184":"AB_2682409"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"1.9","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"3.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"696.5","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"6.6","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"1.6","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.1","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"CIB1","Gene synonym":["CIB","KIP","SIP2-28"],"Ensembl":"ENSG00000185043","Gene description":"Calcium and integrin binding 1","Uniprot":["Q99828"],"Chromosome":"15","Position":"90229975-90234047","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Angiogenesis","Apoptosis","Cell adhesion","Cell cycle","Cell division","Differentiation","Spermatogenesis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"1385.8","Respiratory ciliated cells":"1103.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012991","HPA042413","HPA048825"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB012991":"AB_2533205","HPA042413":"AB_2732498","HPA048825":"AB_2680533"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.26e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.29e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Tissue RNA - adipose tissue [nTPM]":"65.6","Tissue RNA - adrenal gland [nTPM]":"163.6","Tissue RNA - amygdala [nTPM]":"65.4","Tissue RNA - appendix [nTPM]":"79.7","Tissue RNA - basal ganglia [nTPM]":"69.2","Tissue RNA - bone marrow [nTPM]":"205.5","Tissue RNA - breast [nTPM]":"67.4","Tissue RNA - cerebellum [nTPM]":"67.8","Tissue RNA - cerebral cortex [nTPM]":"76.5","Tissue RNA - cervix [nTPM]":"93.8","Tissue RNA - choroid plexus [nTPM]":"96.7","Tissue RNA - colon [nTPM]":"147.9","Tissue RNA - duodenum [nTPM]":"130.1","Tissue RNA - endometrium 1 [nTPM]":"44.6","Tissue RNA - epididymis [nTPM]":"88.1","Tissue RNA - esophagus [nTPM]":"127.3","Tissue RNA - fallopian tube [nTPM]":"146.6","Tissue RNA - gallbladder [nTPM]":"77.4","Tissue RNA - heart muscle [nTPM]":"101.9","Tissue RNA - hippocampal formation [nTPM]":"62.7","Tissue RNA - hypothalamus [nTPM]":"68.8","Tissue RNA - kidney [nTPM]":"220.1","Tissue RNA - liver [nTPM]":"195.7","Tissue RNA - lung [nTPM]":"86.7","Tissue RNA - lymph node [nTPM]":"97.0","Tissue RNA - medulla oblongata [nTPM]":"70.1","Tissue RNA - midbrain [nTPM]":"70.3","Tissue RNA - ovary [nTPM]":"43.9","Tissue RNA - pancreas [nTPM]":"214.1","Tissue RNA - parathyroid gland [nTPM]":"98.3","Tissue RNA - pituitary gland [nTPM]":"93.0","Tissue RNA - placenta [nTPM]":"38.0","Tissue RNA - pons [nTPM]":"68.7","Tissue RNA - prostate [nTPM]":"127.6","Tissue RNA - rectum [nTPM]":"138.1","Tissue RNA - retina [nTPM]":"29.1","Tissue RNA - salivary gland [nTPM]":"116.6","Tissue RNA - seminal vesicle [nTPM]":"72.7","Tissue RNA - skeletal muscle [nTPM]":"58.8","Tissue RNA - skin 1 [nTPM]":"40.4","Tissue RNA - small intestine [nTPM]":"128.5","Tissue RNA - smooth muscle [nTPM]":"45.3","Tissue RNA - spinal cord [nTPM]":"69.3","Tissue RNA - spleen [nTPM]":"117.0","Tissue RNA - stomach 1 [nTPM]":"99.3","Tissue RNA - testis [nTPM]":"113.8","Tissue RNA - thalamus [nTPM]":"69.2","Tissue RNA - thymus [nTPM]":"64.4","Tissue RNA - thyroid gland [nTPM]":"89.1","Tissue RNA - tongue [nTPM]":"42.3","Tissue RNA - tonsil [nTPM]":"120.9","Tissue RNA - urinary bladder [nTPM]":"93.7","Tissue RNA - vagina [nTPM]":"68.3","Tissue RNA - white matter [nTPM]":"69.3","Cell RNA - A-431 [nTPM]":"119.5","Cell RNA - A549 [nTPM]":"261.4","Cell RNA - AF22 [nTPM]":"23.8","Cell RNA - AN3-CA [nTPM]":"83.7","Cell RNA - ASC diff [nTPM]":"98.7","Cell RNA - ASC TERT1 [nTPM]":"102.7","Cell RNA - BEWO [nTPM]":"38.9","Cell RNA - BJ [nTPM]":"123.8","Cell RNA - BJ hTERT+ [nTPM]":"107.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"99.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"87.2","Cell RNA - CACO-2 [nTPM]":"104.7","Cell RNA - CAPAN-2 [nTPM]":"207.4","Cell RNA - Daudi [nTPM]":"34.7","Cell RNA - EFO-21 [nTPM]":"129.7","Cell RNA - fHDF\/TERT166 [nTPM]":"144.0","Cell RNA - GAMG [nTPM]":"125.7","Cell RNA - HaCaT [nTPM]":"124.2","Cell RNA - HAP1 [nTPM]":"48.0","Cell RNA - HBEC3-KT [nTPM]":"141.8","Cell RNA - HBF TERT88 [nTPM]":"54.0","Cell RNA - HDLM-2 [nTPM]":"81.9","Cell RNA - HEK 293 [nTPM]":"114.2","Cell RNA - HEL [nTPM]":"77.5","Cell RNA - HeLa [nTPM]":"182.3","Cell RNA - Hep G2 [nTPM]":"175.9","Cell RNA - HHSteC [nTPM]":"96.2","Cell RNA - HL-60 [nTPM]":"155.2","Cell RNA - HMC-1 [nTPM]":"71.4","Cell RNA - HSkMC [nTPM]":"72.2","Cell RNA - hTCEpi [nTPM]":"84.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"91.9","Cell RNA - hTERT-HME1 [nTPM]":"64.6","Cell RNA - hTERT-RPE1 [nTPM]":"113.7","Cell RNA - HUVEC TERT2 [nTPM]":"129.1","Cell RNA - JURKAT [nTPM]":"83.7","Cell RNA - K-562 [nTPM]":"105.8","Cell RNA - Karpas-707 [nTPM]":"53.5","Cell RNA - LHCN-M2 [nTPM]":"76.4","Cell RNA - MCF7 [nTPM]":"233.3","Cell RNA - MOLT-4 [nTPM]":"118.4","Cell RNA - NB-4 [nTPM]":"179.4","Cell RNA - NTERA-2 [nTPM]":"36.7","Cell RNA - OE19 [nTPM]":"223.9","Cell RNA - PC-3 [nTPM]":"134.0","Cell RNA - REH [nTPM]":"66.1","Cell RNA - RH-30 [nTPM]":"62.8","Cell RNA - RPMI-8226 [nTPM]":"139.7","Cell RNA - RPTEC TERT1 [nTPM]":"256.1","Cell RNA - RT4 [nTPM]":"199.4","Cell RNA - SCLC-21H [nTPM]":"18.7","Cell RNA - SH-SY5Y [nTPM]":"22.8","Cell RNA - SiHa [nTPM]":"168.7","Cell RNA - SK-BR-3 [nTPM]":"136.5","Cell RNA - SK-MEL-30 [nTPM]":"135.7","Cell RNA - SuSa [nTPM]":"41.5","Cell RNA - T-47d [nTPM]":"105.3","Cell RNA - THP-1 [nTPM]":"93.3","Cell RNA - TIME [nTPM]":"81.7","Cell RNA - U-138 MG [nTPM]":"109.6","Cell RNA - U-2 OS [nTPM]":"77.0","Cell RNA - U-2197 [nTPM]":"132.0","Cell RNA - U-251 MG [nTPM]":"153.2","Cell RNA - U-266\/70 [nTPM]":"73.0","Cell RNA - U-266\/84 [nTPM]":"122.0","Cell RNA - U-698 [nTPM]":"40.3","Cell RNA - U-87 MG [nTPM]":"176.1","Cell RNA - U-937 [nTPM]":"174.9","Cell RNA - WM-115 [nTPM]":"47.8","Blood RNA - basophil [nTPM]":"168.9","Blood RNA - classical monocyte [nTPM]":"201.8","Blood RNA - eosinophil [nTPM]":"271.3","Blood RNA - gdT-cell [nTPM]":"226.9","Blood RNA - intermediate monocyte [nTPM]":"248.9","Blood RNA - MAIT T-cell [nTPM]":"188.0","Blood RNA - memory B-cell [nTPM]":"476.4","Blood RNA - memory CD4 T-cell [nTPM]":"269.9","Blood RNA - memory CD8 T-cell [nTPM]":"249.4","Blood RNA - myeloid DC [nTPM]":"224.4","Blood RNA - naive B-cell [nTPM]":"418.0","Blood RNA - naive CD4 T-cell [nTPM]":"221.5","Blood RNA - naive CD8 T-cell [nTPM]":"218.0","Blood RNA - neutrophil [nTPM]":"118.2","Blood RNA - NK-cell [nTPM]":"205.7","Blood RNA - non-classical monocyte [nTPM]":"230.0","Blood RNA - plasmacytoid DC [nTPM]":"149.7","Blood RNA - T-reg [nTPM]":"245.8","Blood RNA - total PBMC [nTPM]":"399.6","Brain RNA - amygdala [nTPM]":"65.4","Brain RNA - basal ganglia [nTPM]":"69.2","Brain RNA - cerebellum [nTPM]":"67.8","Brain RNA - cerebral cortex [nTPM]":"76.5","Brain RNA - hippocampal formation [nTPM]":"62.7","Brain RNA - hypothalamus [nTPM]":"68.8","Brain RNA - medulla oblongata [nTPM]":"70.1","Brain RNA - midbrain [nTPM]":"70.3","Brain RNA - pons [nTPM]":"68.7","Brain RNA - spinal cord [nTPM]":"69.3","Brain RNA - thalamus [nTPM]":"69.2","Brain RNA - white matter [nTPM]":"69.3","Single Cell Type RNA - Adipocytes [nTPM]":"77.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"89.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"104.2","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"203.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"85.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"253.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"520.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"84.8","Single Cell Type RNA - Bipolar cells [nTPM]":"12.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"152.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"118.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"86.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"128.7","Single Cell Type RNA - Club cells [nTPM]":"469.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"183.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"106.7","Single Cell Type RNA - dendritic cells [nTPM]":"198.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"670.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"453.9","Single Cell Type RNA - Ductal cells [nTPM]":"372.1","Single Cell Type RNA - Early spermatids [nTPM]":"380.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"480.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"101.3","Single Cell Type RNA - Endothelial cells [nTPM]":"83.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"97.1","Single Cell Type RNA - Erythroid cells [nTPM]":"62.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"662.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"117.6","Single Cell Type RNA - Fibroblasts [nTPM]":"96.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"149.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"222.8","Single Cell Type RNA - granulocytes [nTPM]":"138.8","Single Cell Type RNA - Granulosa cells [nTPM]":"66.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"79.6","Single Cell Type RNA - Hepatocytes [nTPM]":"230.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"209.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"379.5","Single Cell Type RNA - Ionocytes [nTPM]":"463.9","Single Cell Type RNA - Kupffer cells [nTPM]":"102.5","Single Cell Type RNA - Langerhans cells [nTPM]":"148.0","Single Cell Type RNA - Late spermatids [nTPM]":"1385.8","Single Cell Type RNA - Leydig cells [nTPM]":"105.3","Single Cell Type RNA - Macrophages [nTPM]":"180.5","Single Cell Type RNA - Melanocytes [nTPM]":"128.1","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"187.5","Single Cell Type RNA - Muller glia cells [nTPM]":"138.4","Single Cell Type RNA - NK-cells [nTPM]":"184.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"620.2","Single Cell Type RNA - Paneth cells [nTPM]":"794.2","Single Cell Type RNA - Peritubular cells [nTPM]":"92.6","Single Cell Type RNA - Plasma cells [nTPM]":"88.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"699.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"661.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"668.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1103.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.5","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"62.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"140.4","Single Cell Type RNA - Spermatocytes [nTPM]":"160.3","Single Cell Type RNA - Spermatogonia [nTPM]":"69.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"218.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"67.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"66.1","Single Cell Type RNA - T-cells [nTPM]":"227.5","Single Cell Type RNA - Theca cells [nTPM]":"91.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"315.5","Single Cell Type RNA - Urothelial cells [nTPM]":"577.8"},{"Gene":"CLDN10","Gene synonym":["CPETRL3","OSP-L"],"Ensembl":"ENSG00000134873","Gene description":"Claudin 10","Uniprot":["P78369"],"Chromosome":"13","Position":"95433604-95579759","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Ion transport","Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"kidney":"135.2","pancreas":"216.5","salivary gland":"91.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"182.4","Cholangiocytes":"328.8","Club cells":"251.6","Ductal cells":"394.1","Glandular and luminal cells":"220.2","Proximal tubular cells":"285.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"pancreatic cancer":"19.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"eosinophil":"1.3","neutrophil":"4.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"granulocytes":"4.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HUVEC TERT2":"14.9","NTERA-2":"12.7","RPTEC TERT1":"29.0","SuSa":"73.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012969","HPA042348"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB012969":"AB_2533386","HPA042348":"AB_2677955"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.46e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.13e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-3"},"Tissue RNA - adipose tissue [nTPM]":"1.0","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"33.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"31.3","Tissue RNA - bone marrow [nTPM]":"3.2","Tissue RNA - breast [nTPM]":"3.1","Tissue RNA - cerebellum [nTPM]":"28.6","Tissue RNA - cerebral cortex [nTPM]":"45.8","Tissue RNA - cervix [nTPM]":"30.4","Tissue RNA - choroid plexus [nTPM]":"24.1","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"1.1","Tissue RNA - endometrium 1 [nTPM]":"9.3","Tissue RNA - epididymis [nTPM]":"20.8","Tissue RNA - esophagus [nTPM]":"7.9","Tissue RNA - fallopian tube [nTPM]":"19.2","Tissue RNA - gallbladder [nTPM]":"25.5","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"32.6","Tissue RNA - hypothalamus [nTPM]":"30.5","Tissue RNA - kidney [nTPM]":"135.2","Tissue RNA - liver [nTPM]":"3.7","Tissue RNA - lung [nTPM]":"2.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"27.9","Tissue RNA - midbrain [nTPM]":"30.2","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"216.5","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"3.1","Tissue RNA - placenta [nTPM]":"0.8","Tissue RNA - pons [nTPM]":"27.2","Tissue RNA - prostate [nTPM]":"1.3","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"2.7","Tissue RNA - salivary gland [nTPM]":"91.5","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"16.8","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"27.4","Tissue RNA - spleen [nTPM]":"0.7","Tissue RNA - stomach 1 [nTPM]":"0.9","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"30.1","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"27.4","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"29.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.9","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"2.7","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"4.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.3","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"3.9","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"1.9","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"2.9","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.5","Cell RNA - HUVEC TERT2 [nTPM]":"14.9","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"12.7","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"29.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"73.3","Cell RNA - T-47d [nTPM]":"0.7","Cell RNA - THP-1 [nTPM]":"1.8","Cell RNA - TIME [nTPM]":"0.6","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"1.3","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"4.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"33.0","Brain RNA - basal ganglia [nTPM]":"31.3","Brain RNA - cerebellum [nTPM]":"28.6","Brain RNA - cerebral cortex [nTPM]":"45.8","Brain RNA - hippocampal formation [nTPM]":"32.6","Brain RNA - hypothalamus [nTPM]":"30.5","Brain RNA - medulla oblongata [nTPM]":"27.9","Brain RNA - midbrain [nTPM]":"30.2","Brain RNA - pons [nTPM]":"27.2","Brain RNA - spinal cord [nTPM]":"27.4","Brain RNA - thalamus [nTPM]":"30.1","Brain RNA - white matter [nTPM]":"29.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"93.4","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"182.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"328.8","Single Cell Type RNA - Club cells [nTPM]":"251.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"99.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"135.0","Single Cell Type RNA - Ductal cells [nTPM]":"394.1","Single Cell Type RNA - Early spermatids [nTPM]":"3.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"83.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"28.5","Single Cell Type RNA - Endothelial cells [nTPM]":"4.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"82.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.9","Single Cell Type RNA - Fibroblasts [nTPM]":"1.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"220.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"77.3","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"2.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.8","Single Cell Type RNA - Melanocytes [nTPM]":"69.4","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"78.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"33.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"103.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"22.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"285.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"43.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.8","Single Cell Type RNA - Spermatocytes [nTPM]":"12.2","Single Cell Type RNA - Spermatogonia [nTPM]":"19.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.1","Single Cell Type RNA - T-cells [nTPM]":"2.2","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"5.0"},{"Gene":"COL6A5","Gene synonym":["COL29A1","FLJ35880","VWA4"],"Ensembl":"ENSG00000172752","Gene description":"Collagen type VI alpha 5 chain","Uniprot":[],"Chromosome":"3","Position":"130345516-130484844","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"lung":"5.6","skin 1":"6.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Basal keratinocytes":"3.4","Early spermatids":"5.6","Erythroid cells":"3.8","Fibroblasts":"5.5","Langerhans cells":"5.2","Late spermatids":"3.0","Suprabasal keratinocytes":"3.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"midbrain":"1.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"64","RNA cell line specific nTPM":{"HDLM-2":"15.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043138"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043138":"AB_10796687"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-6"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.58e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.9","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"5.6","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"1.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"6.2","Tissue RNA - small intestine [nTPM]":"0.7","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"1.0","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"1.2","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"15.8","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"1.1","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"5.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"5.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"5.2","Single Cell Type RNA - Late spermatids [nTPM]":"3.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"COL7A1","Gene synonym":["EBD1","EBDCT","EBR1"],"Ensembl":"ENSG00000114270","Gene description":"Collagen type VII alpha 1 chain","Uniprot":["Q02388"],"Chromosome":"3","Position":"48564073-48595329","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Protease inhibitor","Serine protease inhibitor"],"Disease involvement":["Disease variant","Epidermolysis bullosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"98.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"72.5","Basal respiratory cells":"59.3","Basal squamous epithelial cells":"67.2","Endometrial stromal cells":"45.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"41.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"65.7","HaCaT":"63.5","HBEC3-KT":"100.6","HDLM-2":"97.8","HeLa":"146.2","SiHa":"82.8"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016357","HPA018877","HPA042420"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Vesicles"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6000","Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB016357":"AB_2229746","HPA018877":null,"HPA042420":"AB_2677990"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.31e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.86e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.8","Tissue RNA - adrenal gland [nTPM]":"1.1","Tissue RNA - amygdala [nTPM]":"1.4","Tissue RNA - appendix [nTPM]":"3.8","Tissue RNA - basal ganglia [nTPM]":"1.0","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"4.9","Tissue RNA - cerebellum [nTPM]":"2.8","Tissue RNA - cerebral cortex [nTPM]":"2.1","Tissue RNA - cervix [nTPM]":"24.3","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"2.9","Tissue RNA - duodenum [nTPM]":"1.7","Tissue RNA - endometrium 1 [nTPM]":"12.1","Tissue RNA - epididymis [nTPM]":"6.7","Tissue RNA - esophagus [nTPM]":"21.8","Tissue RNA - fallopian tube [nTPM]":"6.4","Tissue RNA - gallbladder [nTPM]":"4.0","Tissue RNA - heart muscle [nTPM]":"3.2","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"6.5","Tissue RNA - kidney [nTPM]":"7.4","Tissue RNA - liver [nTPM]":"1.3","Tissue RNA - lung [nTPM]":"1.7","Tissue RNA - lymph node [nTPM]":"1.2","Tissue RNA - medulla oblongata [nTPM]":"7.0","Tissue RNA - midbrain [nTPM]":"3.2","Tissue RNA - ovary [nTPM]":"3.4","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"2.5","Tissue RNA - placenta [nTPM]":"1.6","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"34.2","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"1.4","Tissue RNA - salivary gland [nTPM]":"11.5","Tissue RNA - seminal vesicle [nTPM]":"12.2","Tissue RNA - skeletal muscle [nTPM]":"3.5","Tissue RNA - skin 1 [nTPM]":"98.2","Tissue RNA - small intestine [nTPM]":"4.1","Tissue RNA - smooth muscle [nTPM]":"2.5","Tissue RNA - spinal cord [nTPM]":"2.6","Tissue RNA - spleen [nTPM]":"6.5","Tissue RNA - stomach 1 [nTPM]":"2.1","Tissue RNA - testis [nTPM]":"3.6","Tissue RNA - thalamus [nTPM]":"6.5","Tissue RNA - thymus [nTPM]":"1.2","Tissue RNA - thyroid gland [nTPM]":"0.5","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"1.3","Tissue RNA - urinary bladder [nTPM]":"6.6","Tissue RNA - vagina [nTPM]":"29.2","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"25.4","Cell RNA - AF22 [nTPM]":"1.2","Cell RNA - AN3-CA [nTPM]":"0.5","Cell RNA - ASC diff [nTPM]":"9.2","Cell RNA - ASC TERT1 [nTPM]":"12.3","Cell RNA - BEWO [nTPM]":"31.0","Cell RNA - BJ [nTPM]":"65.7","Cell RNA - BJ hTERT+ [nTPM]":"40.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.0","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"0.5","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"2.0","Cell RNA - fHDF\/TERT166 [nTPM]":"15.0","Cell RNA - GAMG [nTPM]":"15.4","Cell RNA - HaCaT [nTPM]":"63.5","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"100.6","Cell RNA - HBF TERT88 [nTPM]":"3.1","Cell RNA - HDLM-2 [nTPM]":"97.8","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"146.2","Cell RNA - Hep G2 [nTPM]":"4.3","Cell RNA - HHSteC [nTPM]":"25.6","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"19.9","Cell RNA - hTCEpi [nTPM]":"58.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"34.4","Cell RNA - hTERT-HME1 [nTPM]":"26.8","Cell RNA - hTERT-RPE1 [nTPM]":"23.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"2.0","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.9","Cell RNA - NTERA-2 [nTPM]":"3.1","Cell RNA - OE19 [nTPM]":"1.3","Cell RNA - PC-3 [nTPM]":"1.3","Cell RNA - REH [nTPM]":"0.5","Cell RNA - RH-30 [nTPM]":"2.2","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"9.2","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"82.8","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"3.7","Cell RNA - T-47d [nTPM]":"1.3","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"5.6","Cell RNA - U-2 OS [nTPM]":"3.2","Cell RNA - U-2197 [nTPM]":"3.2","Cell RNA - U-251 MG [nTPM]":"50.1","Cell RNA - U-266\/70 [nTPM]":"1.8","Cell RNA - U-266\/84 [nTPM]":"1.8","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"49.0","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"2.8","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.4","Brain RNA - basal ganglia [nTPM]":"1.0","Brain RNA - cerebellum [nTPM]":"2.8","Brain RNA - cerebral cortex [nTPM]":"2.1","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"6.5","Brain RNA - medulla oblongata [nTPM]":"7.0","Brain RNA - midbrain [nTPM]":"3.2","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"2.6","Brain RNA - thalamus [nTPM]":"6.5","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"72.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"59.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"67.2","Single Cell Type RNA - Bipolar cells [nTPM]":"17.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"10.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.9","Single Cell Type RNA - Early spermatids [nTPM]":"11.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"45.3","Single Cell Type RNA - Endothelial cells [nTPM]":"1.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.0","Single Cell Type RNA - Fibroblasts [nTPM]":"8.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.6","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"4.2","Single Cell Type RNA - Late spermatids [nTPM]":"6.3","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"0.8","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"2.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"5.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.4","Single Cell Type RNA - Spermatocytes [nTPM]":"2.6","Single Cell Type RNA - Spermatogonia [nTPM]":"1.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"5.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"5.8"},{"Gene":"CTNNB1","Gene synonym":["armadillo","beta-catenin","CTNNB"],"Ensembl":"ENSG00000168036","Gene description":"Catenin beta 1","Uniprot":["P35222"],"Chromosome":"3","Position":"41194741-41260096","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell adhesion","Host-virus interaction","Neurogenesis","Transcription","Transcription regulation","Wnt signaling pathway"],"Molecular function":["Activator"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"539.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000108","CAB001950","HPA029159","HPA029160"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB000108":null,"CAB001950":null,"HPA029159":"AB_10599619","HPA029160":"AB_10600996"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.54e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-2"},"Tissue RNA - adipose tissue [nTPM]":"130.8","Tissue RNA - adrenal gland [nTPM]":"112.2","Tissue RNA - amygdala [nTPM]":"106.7","Tissue RNA - appendix [nTPM]":"98.7","Tissue RNA - basal ganglia [nTPM]":"85.3","Tissue RNA - bone marrow [nTPM]":"162.4","Tissue RNA - breast [nTPM]":"194.3","Tissue RNA - cerebellum [nTPM]":"147.8","Tissue RNA - cerebral cortex [nTPM]":"87.5","Tissue RNA - cervix [nTPM]":"179.4","Tissue RNA - choroid plexus [nTPM]":"94.7","Tissue RNA - colon [nTPM]":"141.2","Tissue RNA - duodenum [nTPM]":"136.9","Tissue RNA - endometrium 1 [nTPM]":"149.4","Tissue RNA - epididymis [nTPM]":"84.4","Tissue RNA - esophagus [nTPM]":"113.7","Tissue RNA - fallopian tube [nTPM]":"131.0","Tissue RNA - gallbladder [nTPM]":"121.8","Tissue RNA - heart muscle [nTPM]":"109.9","Tissue RNA - hippocampal formation [nTPM]":"88.1","Tissue RNA - hypothalamus [nTPM]":"105.3","Tissue RNA - kidney [nTPM]":"106.5","Tissue RNA - liver [nTPM]":"147.9","Tissue RNA - lung [nTPM]":"132.9","Tissue RNA - lymph node [nTPM]":"81.9","Tissue RNA - medulla oblongata [nTPM]":"101.3","Tissue RNA - midbrain [nTPM]":"112.9","Tissue RNA - ovary [nTPM]":"173.9","Tissue RNA - pancreas [nTPM]":"93.3","Tissue RNA - parathyroid gland [nTPM]":"137.2","Tissue RNA - pituitary gland [nTPM]":"84.7","Tissue RNA - placenta [nTPM]":"200.0","Tissue RNA - pons [nTPM]":"94.0","Tissue RNA - prostate [nTPM]":"132.3","Tissue RNA - rectum [nTPM]":"134.5","Tissue RNA - retina [nTPM]":"88.8","Tissue RNA - salivary gland [nTPM]":"110.9","Tissue RNA - seminal vesicle [nTPM]":"126.3","Tissue RNA - skeletal muscle [nTPM]":"87.3","Tissue RNA - skin 1 [nTPM]":"99.0","Tissue RNA - small intestine [nTPM]":"142.9","Tissue RNA - smooth muscle [nTPM]":"178.4","Tissue RNA - spinal cord [nTPM]":"104.9","Tissue RNA - spleen [nTPM]":"92.5","Tissue RNA - stomach 1 [nTPM]":"81.8","Tissue RNA - testis [nTPM]":"59.5","Tissue RNA - thalamus [nTPM]":"129.4","Tissue RNA - thymus [nTPM]":"95.6","Tissue RNA - thyroid gland [nTPM]":"140.6","Tissue RNA - tongue [nTPM]":"89.9","Tissue RNA - tonsil [nTPM]":"99.5","Tissue RNA - urinary bladder [nTPM]":"158.3","Tissue RNA - vagina [nTPM]":"109.3","Tissue RNA - white matter [nTPM]":"108.4","Cell RNA - A-431 [nTPM]":"161.6","Cell RNA - A549 [nTPM]":"210.0","Cell RNA - AF22 [nTPM]":"423.6","Cell RNA - AN3-CA [nTPM]":"242.8","Cell RNA - ASC diff [nTPM]":"226.9","Cell RNA - ASC TERT1 [nTPM]":"184.7","Cell RNA - BEWO [nTPM]":"333.8","Cell RNA - BJ [nTPM]":"179.6","Cell RNA - BJ hTERT+ [nTPM]":"249.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"288.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"284.3","Cell RNA - CACO-2 [nTPM]":"146.3","Cell RNA - CAPAN-2 [nTPM]":"224.0","Cell RNA - Daudi [nTPM]":"131.7","Cell RNA - EFO-21 [nTPM]":"157.8","Cell RNA - fHDF\/TERT166 [nTPM]":"314.1","Cell RNA - GAMG [nTPM]":"129.0","Cell RNA - HaCaT [nTPM]":"119.6","Cell RNA - HAP1 [nTPM]":"315.8","Cell RNA - HBEC3-KT [nTPM]":"510.0","Cell RNA - HBF TERT88 [nTPM]":"306.2","Cell RNA - HDLM-2 [nTPM]":"123.3","Cell RNA - HEK 293 [nTPM]":"215.7","Cell RNA - HEL [nTPM]":"215.5","Cell RNA - HeLa [nTPM]":"261.0","Cell RNA - Hep G2 [nTPM]":"523.7","Cell RNA - HHSteC [nTPM]":"169.5","Cell RNA - HL-60 [nTPM]":"121.8","Cell RNA - HMC-1 [nTPM]":"99.1","Cell RNA - HSkMC [nTPM]":"271.6","Cell RNA - hTCEpi [nTPM]":"226.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"345.5","Cell RNA - hTERT-HME1 [nTPM]":"208.7","Cell RNA - hTERT-RPE1 [nTPM]":"235.7","Cell RNA - HUVEC TERT2 [nTPM]":"258.1","Cell RNA - JURKAT [nTPM]":"63.0","Cell RNA - K-562 [nTPM]":"153.7","Cell RNA - Karpas-707 [nTPM]":"80.3","Cell RNA - LHCN-M2 [nTPM]":"324.1","Cell RNA - MCF7 [nTPM]":"161.8","Cell RNA - MOLT-4 [nTPM]":"87.3","Cell RNA - NB-4 [nTPM]":"68.3","Cell RNA - NTERA-2 [nTPM]":"397.2","Cell RNA - OE19 [nTPM]":"211.0","Cell RNA - PC-3 [nTPM]":"159.3","Cell RNA - REH [nTPM]":"64.9","Cell RNA - RH-30 [nTPM]":"281.9","Cell RNA - RPMI-8226 [nTPM]":"88.3","Cell RNA - RPTEC TERT1 [nTPM]":"177.9","Cell RNA - RT4 [nTPM]":"494.8","Cell RNA - SCLC-21H [nTPM]":"102.9","Cell RNA - SH-SY5Y [nTPM]":"172.4","Cell RNA - SiHa [nTPM]":"296.2","Cell RNA - SK-BR-3 [nTPM]":"147.1","Cell RNA - SK-MEL-30 [nTPM]":"809.4","Cell RNA - SuSa [nTPM]":"509.8","Cell RNA - T-47d [nTPM]":"242.1","Cell RNA - THP-1 [nTPM]":"248.6","Cell RNA - TIME [nTPM]":"340.8","Cell RNA - U-138 MG [nTPM]":"217.1","Cell RNA - U-2 OS [nTPM]":"163.6","Cell RNA - U-2197 [nTPM]":"139.3","Cell RNA - U-251 MG [nTPM]":"264.0","Cell RNA - U-266\/70 [nTPM]":"50.7","Cell RNA - U-266\/84 [nTPM]":"82.7","Cell RNA - U-698 [nTPM]":"138.4","Cell RNA - U-87 MG [nTPM]":"221.5","Cell RNA - U-937 [nTPM]":"150.5","Cell RNA - WM-115 [nTPM]":"369.7","Blood RNA - basophil [nTPM]":"4.7","Blood RNA - classical monocyte [nTPM]":"7.3","Blood RNA - eosinophil [nTPM]":"6.4","Blood RNA - gdT-cell [nTPM]":"9.2","Blood RNA - intermediate monocyte [nTPM]":"12.3","Blood RNA - MAIT T-cell [nTPM]":"10.9","Blood RNA - memory B-cell [nTPM]":"7.7","Blood RNA - memory CD4 T-cell [nTPM]":"8.6","Blood RNA - memory CD8 T-cell [nTPM]":"10.1","Blood RNA - myeloid DC [nTPM]":"11.8","Blood RNA - naive B-cell [nTPM]":"8.0","Blood RNA - naive CD4 T-cell [nTPM]":"8.6","Blood RNA - naive CD8 T-cell [nTPM]":"9.4","Blood RNA - neutrophil [nTPM]":"6.6","Blood RNA - NK-cell [nTPM]":"9.6","Blood RNA - non-classical monocyte [nTPM]":"12.6","Blood RNA - plasmacytoid DC [nTPM]":"10.0","Blood RNA - T-reg [nTPM]":"10.8","Blood RNA - total PBMC [nTPM]":"5.6","Brain RNA - amygdala [nTPM]":"106.7","Brain RNA - basal ganglia [nTPM]":"85.3","Brain RNA - cerebellum [nTPM]":"147.8","Brain RNA - cerebral cortex [nTPM]":"87.5","Brain RNA - hippocampal formation [nTPM]":"88.1","Brain RNA - hypothalamus [nTPM]":"105.3","Brain RNA - medulla oblongata [nTPM]":"101.3","Brain RNA - midbrain [nTPM]":"112.9","Brain RNA - pons [nTPM]":"94.0","Brain RNA - spinal cord [nTPM]":"104.9","Brain RNA - thalamus [nTPM]":"129.4","Brain RNA - white matter [nTPM]":"108.4","Single Cell Type RNA - Adipocytes [nTPM]":"171.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"137.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"179.5","Single Cell Type RNA - Astrocytes [nTPM]":"58.1","Single Cell Type RNA - B-cells [nTPM]":"71.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"213.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"130.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"75.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"116.1","Single Cell Type RNA - Bipolar cells [nTPM]":"40.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"232.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"168.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"84.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"90.1","Single Cell Type RNA - Club cells [nTPM]":"119.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"62.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"318.9","Single Cell Type RNA - dendritic cells [nTPM]":"99.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"251.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"132.2","Single Cell Type RNA - Early spermatids [nTPM]":"11.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"90.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"125.9","Single Cell Type RNA - Endothelial cells [nTPM]":"187.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"93.8","Single Cell Type RNA - Erythroid cells [nTPM]":"43.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"50.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"78.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"115.6","Single Cell Type RNA - Fibroblasts [nTPM]":"116.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"53.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"95.5","Single Cell Type RNA - granulocytes [nTPM]":"116.6","Single Cell Type RNA - Granulosa cells [nTPM]":"137.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"139.2","Single Cell Type RNA - Hepatocytes [nTPM]":"172.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"115.1","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"82.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"145.9","Single Cell Type RNA - Ionocytes [nTPM]":"42.7","Single Cell Type RNA - Kupffer cells [nTPM]":"154.6","Single Cell Type RNA - Langerhans cells [nTPM]":"228.1","Single Cell Type RNA - Late spermatids [nTPM]":"9.5","Single Cell Type RNA - Leydig cells [nTPM]":"59.7","Single Cell Type RNA - Macrophages [nTPM]":"161.1","Single Cell Type RNA - Melanocytes [nTPM]":"202.7","Single Cell Type RNA - Microglial cells [nTPM]":"124.6","Single Cell Type RNA - monocytes [nTPM]":"98.3","Single Cell Type RNA - Muller glia cells [nTPM]":"89.2","Single Cell Type RNA - NK-cells [nTPM]":"49.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"70.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"62.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"139.8","Single Cell Type RNA - Paneth cells [nTPM]":"249.5","Single Cell Type RNA - Peritubular cells [nTPM]":"86.9","Single Cell Type RNA - Plasma cells [nTPM]":"55.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"128.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"160.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"93.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"96.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"62.0","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"175.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"137.3","Single Cell Type RNA - Spermatocytes [nTPM]":"78.4","Single Cell Type RNA - Spermatogonia [nTPM]":"40.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"70.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"174.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"539.5","Single Cell Type RNA - T-cells [nTPM]":"77.0","Single Cell Type RNA - Theca cells [nTPM]":"245.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"189.6","Single Cell Type RNA - Urothelial cells [nTPM]":"127.9"},{"Gene":"CYLD","Gene synonym":["CYLD1","KIAA0849","USPL2"],"Ensembl":"ENSG00000083799","Gene description":"CYLD lysine 63 deubiquitinase","Uniprot":["Q9NQC7"],"Chromosome":"16","Position":"50742050-50801935","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","Immunity","Innate immunity","Ubl conjugation pathway","Wnt signaling pathway"],"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"94.3"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"136.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011713","HPA050095"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Centriolar satellite"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Centriolar satellite"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB011713":"AB_731794","HPA050095":"AB_2681013"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.42e-2"},"Tissue RNA - adipose tissue [nTPM]":"14.3","Tissue RNA - adrenal gland [nTPM]":"22.0","Tissue RNA - amygdala [nTPM]":"23.9","Tissue RNA - appendix [nTPM]":"38.8","Tissue RNA - basal ganglia [nTPM]":"23.5","Tissue RNA - bone marrow [nTPM]":"94.3","Tissue RNA - breast [nTPM]":"13.6","Tissue RNA - cerebellum [nTPM]":"17.9","Tissue RNA - cerebral cortex [nTPM]":"18.2","Tissue RNA - cervix [nTPM]":"13.0","Tissue RNA - choroid plexus [nTPM]":"22.3","Tissue RNA - colon [nTPM]":"16.3","Tissue RNA - duodenum [nTPM]":"16.1","Tissue RNA - endometrium 1 [nTPM]":"15.1","Tissue RNA - epididymis [nTPM]":"12.1","Tissue RNA - esophagus [nTPM]":"23.3","Tissue RNA - fallopian tube [nTPM]":"11.0","Tissue RNA - gallbladder [nTPM]":"20.5","Tissue RNA - heart muscle [nTPM]":"20.1","Tissue RNA - hippocampal formation [nTPM]":"17.3","Tissue RNA - hypothalamus [nTPM]":"23.3","Tissue RNA - kidney [nTPM]":"14.2","Tissue RNA - liver [nTPM]":"21.0","Tissue RNA - lung [nTPM]":"21.5","Tissue RNA - lymph node [nTPM]":"53.4","Tissue RNA - medulla oblongata [nTPM]":"21.3","Tissue RNA - midbrain [nTPM]":"27.8","Tissue RNA - ovary [nTPM]":"15.4","Tissue RNA - pancreas [nTPM]":"15.2","Tissue RNA - parathyroid gland [nTPM]":"23.0","Tissue RNA - pituitary gland [nTPM]":"15.4","Tissue RNA - placenta [nTPM]":"15.4","Tissue RNA - pons [nTPM]":"23.6","Tissue RNA - prostate [nTPM]":"16.3","Tissue RNA - rectum [nTPM]":"19.3","Tissue RNA - retina [nTPM]":"22.0","Tissue RNA - salivary gland [nTPM]":"18.9","Tissue RNA - seminal vesicle [nTPM]":"16.0","Tissue RNA - skeletal muscle [nTPM]":"34.3","Tissue RNA - skin 1 [nTPM]":"15.2","Tissue RNA - small intestine [nTPM]":"16.2","Tissue RNA - smooth muscle [nTPM]":"16.8","Tissue RNA - spinal cord [nTPM]":"21.6","Tissue RNA - spleen [nTPM]":"39.0","Tissue RNA - stomach 1 [nTPM]":"19.9","Tissue RNA - testis [nTPM]":"38.3","Tissue RNA - thalamus [nTPM]":"32.7","Tissue RNA - thymus [nTPM]":"35.6","Tissue RNA - thyroid gland [nTPM]":"24.9","Tissue RNA - tongue [nTPM]":"20.5","Tissue RNA - tonsil [nTPM]":"48.4","Tissue RNA - urinary bladder [nTPM]":"24.1","Tissue RNA - vagina [nTPM]":"12.9","Tissue RNA - white matter [nTPM]":"24.2","Cell RNA - A-431 [nTPM]":"26.9","Cell RNA - A549 [nTPM]":"8.3","Cell RNA - AF22 [nTPM]":"9.4","Cell RNA - AN3-CA [nTPM]":"10.6","Cell RNA - ASC diff [nTPM]":"14.3","Cell RNA - ASC TERT1 [nTPM]":"21.0","Cell RNA - BEWO [nTPM]":"8.7","Cell RNA - BJ [nTPM]":"39.1","Cell RNA - BJ hTERT+ [nTPM]":"56.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"39.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.4","Cell RNA - CACO-2 [nTPM]":"6.9","Cell RNA - CAPAN-2 [nTPM]":"12.5","Cell RNA - Daudi [nTPM]":"30.7","Cell RNA - EFO-21 [nTPM]":"13.7","Cell RNA - fHDF\/TERT166 [nTPM]":"38.3","Cell RNA - GAMG [nTPM]":"43.4","Cell RNA - HaCaT [nTPM]":"10.3","Cell RNA - HAP1 [nTPM]":"11.3","Cell RNA - HBEC3-KT [nTPM]":"23.7","Cell RNA - HBF TERT88 [nTPM]":"58.7","Cell RNA - HDLM-2 [nTPM]":"136.6","Cell RNA - HEK 293 [nTPM]":"16.6","Cell RNA - HEL [nTPM]":"15.5","Cell RNA - HeLa [nTPM]":"15.3","Cell RNA - Hep G2 [nTPM]":"5.8","Cell RNA - HHSteC [nTPM]":"29.1","Cell RNA - HL-60 [nTPM]":"15.4","Cell RNA - HMC-1 [nTPM]":"69.5","Cell RNA - HSkMC [nTPM]":"23.0","Cell RNA - hTCEpi [nTPM]":"18.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"48.1","Cell RNA - hTERT-HME1 [nTPM]":"50.1","Cell RNA - hTERT-RPE1 [nTPM]":"37.7","Cell RNA - HUVEC TERT2 [nTPM]":"16.3","Cell RNA - JURKAT [nTPM]":"21.3","Cell RNA - K-562 [nTPM]":"6.6","Cell RNA - Karpas-707 [nTPM]":"26.1","Cell RNA - LHCN-M2 [nTPM]":"56.4","Cell RNA - MCF7 [nTPM]":"4.0","Cell RNA - MOLT-4 [nTPM]":"14.4","Cell RNA - NB-4 [nTPM]":"22.3","Cell RNA - NTERA-2 [nTPM]":"10.1","Cell RNA - OE19 [nTPM]":"8.5","Cell RNA - PC-3 [nTPM]":"13.3","Cell RNA - REH [nTPM]":"13.4","Cell RNA - RH-30 [nTPM]":"18.8","Cell RNA - RPMI-8226 [nTPM]":"29.4","Cell RNA - RPTEC TERT1 [nTPM]":"12.9","Cell RNA - RT4 [nTPM]":"9.1","Cell RNA - SCLC-21H [nTPM]":"12.0","Cell RNA - SH-SY5Y [nTPM]":"9.2","Cell RNA - SiHa [nTPM]":"33.1","Cell RNA - SK-BR-3 [nTPM]":"11.2","Cell RNA - SK-MEL-30 [nTPM]":"9.8","Cell RNA - SuSa [nTPM]":"14.3","Cell RNA - T-47d [nTPM]":"11.0","Cell RNA - THP-1 [nTPM]":"18.9","Cell RNA - TIME [nTPM]":"18.6","Cell RNA - U-138 MG [nTPM]":"67.2","Cell RNA - U-2 OS [nTPM]":"15.4","Cell RNA - U-2197 [nTPM]":"23.4","Cell RNA - U-251 MG [nTPM]":"15.9","Cell RNA - U-266\/70 [nTPM]":"68.0","Cell RNA - U-266\/84 [nTPM]":"68.4","Cell RNA - U-698 [nTPM]":"33.2","Cell RNA - U-87 MG [nTPM]":"49.3","Cell RNA - U-937 [nTPM]":"16.7","Cell RNA - WM-115 [nTPM]":"14.7","Blood RNA - basophil [nTPM]":"64.6","Blood RNA - classical monocyte [nTPM]":"15.2","Blood RNA - eosinophil [nTPM]":"38.3","Blood RNA - gdT-cell [nTPM]":"18.1","Blood RNA - intermediate monocyte [nTPM]":"17.7","Blood RNA - MAIT T-cell [nTPM]":"21.8","Blood RNA - memory B-cell [nTPM]":"17.2","Blood RNA - memory CD4 T-cell [nTPM]":"27.1","Blood RNA - memory CD8 T-cell [nTPM]":"24.5","Blood RNA - myeloid DC [nTPM]":"18.3","Blood RNA - naive B-cell [nTPM]":"11.1","Blood RNA - naive CD4 T-cell [nTPM]":"24.4","Blood RNA - naive CD8 T-cell [nTPM]":"19.4","Blood RNA - neutrophil [nTPM]":"32.3","Blood RNA - NK-cell [nTPM]":"25.7","Blood RNA - non-classical monocyte [nTPM]":"18.8","Blood RNA - plasmacytoid DC [nTPM]":"11.0","Blood RNA - T-reg [nTPM]":"37.3","Blood RNA - total PBMC [nTPM]":"19.5","Brain RNA - amygdala [nTPM]":"23.9","Brain RNA - basal ganglia [nTPM]":"23.5","Brain RNA - cerebellum [nTPM]":"17.9","Brain RNA - cerebral cortex [nTPM]":"18.2","Brain RNA - hippocampal formation [nTPM]":"17.3","Brain RNA - hypothalamus [nTPM]":"23.3","Brain RNA - medulla oblongata [nTPM]":"21.3","Brain RNA - midbrain [nTPM]":"27.8","Brain RNA - pons [nTPM]":"23.6","Brain RNA - spinal cord [nTPM]":"21.6","Brain RNA - thalamus [nTPM]":"32.7","Brain RNA - white matter [nTPM]":"24.2","Single Cell Type RNA - Adipocytes [nTPM]":"28.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.8","Single Cell Type RNA - Astrocytes [nTPM]":"31.6","Single Cell Type RNA - B-cells [nTPM]":"87.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"120.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"59.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"32.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"40.9","Single Cell Type RNA - Bipolar cells [nTPM]":"89.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"35.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"26.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"34.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"32.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"93.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.8","Single Cell Type RNA - dendritic cells [nTPM]":"84.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"28.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"20.0","Single Cell Type RNA - Early spermatids [nTPM]":"48.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.9","Single Cell Type RNA - Endothelial cells [nTPM]":"36.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"31.1","Single Cell Type RNA - Erythroid cells [nTPM]":"26.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"51.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.4","Single Cell Type RNA - Fibroblasts [nTPM]":"37.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"22.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"47.1","Single Cell Type RNA - granulocytes [nTPM]":"80.5","Single Cell Type RNA - Granulosa cells [nTPM]":"21.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.8","Single Cell Type RNA - Hepatocytes [nTPM]":"25.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"21.5","Single Cell Type RNA - Horizontal cells [nTPM]":"67.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"54.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.7","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"40.0","Single Cell Type RNA - Langerhans cells [nTPM]":"127.6","Single Cell Type RNA - Late spermatids [nTPM]":"31.3","Single Cell Type RNA - Leydig cells [nTPM]":"25.4","Single Cell Type RNA - Macrophages [nTPM]":"66.4","Single Cell Type RNA - Melanocytes [nTPM]":"74.7","Single Cell Type RNA - Microglial cells [nTPM]":"57.1","Single Cell Type RNA - monocytes [nTPM]":"63.7","Single Cell Type RNA - Muller glia cells [nTPM]":"23.3","Single Cell Type RNA - NK-cells [nTPM]":"70.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"51.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"119.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.0","Single Cell Type RNA - Paneth cells [nTPM]":"22.4","Single Cell Type RNA - Peritubular cells [nTPM]":"21.1","Single Cell Type RNA - Plasma cells [nTPM]":"79.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"66.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"48.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"54.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"30.5","Single Cell Type RNA - Spermatocytes [nTPM]":"59.2","Single Cell Type RNA - Spermatogonia [nTPM]":"15.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"64.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"155.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - T-cells [nTPM]":"119.5","Single Cell Type RNA - Theca cells [nTPM]":"21.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.8","Single Cell Type RNA - Urothelial cells [nTPM]":"66.7"},{"Gene":"DSC3","Gene synonym":["CDHF3","DSC","DSC1","DSC2","DSC4"],"Ensembl":"ENSG00000134762","Gene description":"Desmocollin 3","Uniprot":["Q14574"],"Chromosome":"18","Position":"30989365-31042815","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Hypotrichosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"esophagus":"99.2","skin 1":"372.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Basal keratinocytes":"500.7","Basal squamous epithelial cells":"214.5","Squamous epithelial cells":"419.6","Suprabasal keratinocytes":"688.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"78.6","head and neck cancer":"107.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"246.2","HBEC3-KT":"54.6","hTCEpi":"156.7","hTERT-HME1":"103.6","REH":"44.8"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hippocampal formation":"3.3"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037328","HPA049265","HPA073937"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 61: Squamous epithelial cells - Keratinization","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"CAB037328":null,"HPA049265":"AB_2680695","HPA073937":"AB_2686645"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.44e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.04e-5"},"Tissue RNA - adipose tissue [nTPM]":"4.8","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"12.5","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"23.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"1.2","Tissue RNA - esophagus [nTPM]":"99.2","Tissue RNA - fallopian tube [nTPM]":"1.3","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"3.4","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"12.5","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"6.0","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"19.6","Tissue RNA - seminal vesicle [nTPM]":"1.3","Tissue RNA - skeletal muscle [nTPM]":"1.0","Tissue RNA - skin 1 [nTPM]":"372.6","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"7.7","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"24.7","Tissue RNA - urinary bladder [nTPM]":"3.5","Tissue RNA - vagina [nTPM]":"48.5","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"17.2","Cell RNA - A549 [nTPM]":"1.8","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"6.6","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"246.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"54.6","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"14.6","Cell RNA - HEL [nTPM]":"0.9","Cell RNA - HeLa [nTPM]":"4.7","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"9.7","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"10.2","Cell RNA - hTCEpi [nTPM]":"156.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"103.6","Cell RNA - hTERT-RPE1 [nTPM]":"19.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.9","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"21.8","Cell RNA - REH [nTPM]":"44.8","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.6","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"500.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"62.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"49.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"214.5","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"30.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"73.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"3.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"14.2","Single Cell Type RNA - Fibroblasts [nTPM]":"4.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"34.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"39.2","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"32.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"419.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"688.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.0","Single Cell Type RNA - T-cells [nTPM]":"2.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"89.1"},{"Gene":"DSG4","Gene synonym":["CDHF13","LAH"],"Ensembl":"ENSG00000175065","Gene description":"Desmoglein 4","Uniprot":["Q86SJ6"],"Chromosome":"18","Position":"31376777-31414912","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Disease variant","Hypotrichosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"skin 1":"2.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"1.4","Squamous epithelial cells":"1.0","Urothelial cells":"1.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"133","RNA cell line specific nTPM":{"HaCaT":"37.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059456","HPA079244"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"320000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 61: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA059456":"AB_2684025","HPA079244":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"2.9","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"37.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"ENPP1","Gene synonym":["M6S1","NPPS","PC-1","PCA1","PDNP1"],"Ensembl":"ENSG00000197594","Gene description":"Ectonucleotide pyrophosphatase\/phosphodiesterase 1","Uniprot":["P22413"],"Chromosome":"6","Position":"131808016-131895155","Protein class":["CD markers","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Biomineralization"],"Molecular function":["Hydrolase"],"Disease involvement":["Diabetes mellitus","Disease variant","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"44.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"80.2","Fibroblasts":"56.9","Hepatocytes":"111.6","Peritubular cells":"70.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"1.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"34.1","LHCN-M2":"21.1","U-138 MG":"27.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB032904","HPA062066"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4400000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB032904":"AB_2099635","HPA062066":"AB_2684674"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-3"},"Tissue RNA - adipose tissue [nTPM]":"8.4","Tissue RNA - adrenal gland [nTPM]":"3.1","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"1.4","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"7.1","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"7.1","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"2.3","Tissue RNA - duodenum [nTPM]":"1.8","Tissue RNA - endometrium 1 [nTPM]":"22.1","Tissue RNA - epididymis [nTPM]":"7.4","Tissue RNA - esophagus [nTPM]":"2.3","Tissue RNA - fallopian tube [nTPM]":"6.9","Tissue RNA - gallbladder [nTPM]":"1.2","Tissue RNA - heart muscle [nTPM]":"1.6","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"0.7","Tissue RNA - kidney [nTPM]":"4.2","Tissue RNA - liver [nTPM]":"31.9","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"1.4","Tissue RNA - medulla oblongata [nTPM]":"1.2","Tissue RNA - midbrain [nTPM]":"1.4","Tissue RNA - ovary [nTPM]":"8.3","Tissue RNA - pancreas [nTPM]":"28.5","Tissue RNA - parathyroid gland [nTPM]":"27.8","Tissue RNA - pituitary gland [nTPM]":"10.9","Tissue RNA - placenta [nTPM]":"44.0","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"3.4","Tissue RNA - rectum [nTPM]":"2.0","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"4.2","Tissue RNA - seminal vesicle [nTPM]":"5.8","Tissue RNA - skeletal muscle [nTPM]":"2.7","Tissue RNA - skin 1 [nTPM]":"1.7","Tissue RNA - small intestine [nTPM]":"1.3","Tissue RNA - smooth muscle [nTPM]":"10.2","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"1.9","Tissue RNA - stomach 1 [nTPM]":"1.7","Tissue RNA - testis [nTPM]":"1.6","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"2.2","Tissue RNA - thyroid gland [nTPM]":"20.1","Tissue RNA - tongue [nTPM]":"3.2","Tissue RNA - tonsil [nTPM]":"0.8","Tissue RNA - urinary bladder [nTPM]":"2.7","Tissue RNA - vagina [nTPM]":"4.9","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"1.3","Cell RNA - AF22 [nTPM]":"1.2","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"34.1","Cell RNA - ASC TERT1 [nTPM]":"5.3","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"9.2","Cell RNA - BJ hTERT+ [nTPM]":"9.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.5","Cell RNA - CACO-2 [nTPM]":"4.1","Cell RNA - CAPAN-2 [nTPM]":"1.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.8","Cell RNA - fHDF\/TERT166 [nTPM]":"5.9","Cell RNA - GAMG [nTPM]":"7.2","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.3","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"14.8","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"1.8","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"1.1","Cell RNA - Hep G2 [nTPM]":"12.0","Cell RNA - HHSteC [nTPM]":"1.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"4.2","Cell RNA - HSkMC [nTPM]":"8.8","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.6","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"4.1","Cell RNA - HUVEC TERT2 [nTPM]":"4.3","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"1.8","Cell RNA - LHCN-M2 [nTPM]":"21.1","Cell RNA - MCF7 [nTPM]":"2.6","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"7.9","Cell RNA - OE19 [nTPM]":"1.6","Cell RNA - PC-3 [nTPM]":"1.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"10.2","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"3.4","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"1.3","Cell RNA - SK-MEL-30 [nTPM]":"4.2","Cell RNA - SuSa [nTPM]":"5.7","Cell RNA - T-47d [nTPM]":"3.9","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"2.9","Cell RNA - U-138 MG [nTPM]":"27.6","Cell RNA - U-2 OS [nTPM]":"1.0","Cell RNA - U-2197 [nTPM]":"1.9","Cell RNA - U-251 MG [nTPM]":"9.1","Cell RNA - U-266\/70 [nTPM]":"3.4","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"12.6","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"3.5","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"1.6","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"0.7","Brain RNA - medulla oblongata [nTPM]":"1.2","Brain RNA - midbrain [nTPM]":"1.4","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"2.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"1.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"4.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"4.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"80.2","Single Cell Type RNA - Endothelial cells [nTPM]":"4.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.1","Single Cell Type RNA - Fibroblasts [nTPM]":"56.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"9.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"111.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.6","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.9","Single Cell Type RNA - Langerhans cells [nTPM]":"5.9","Single Cell Type RNA - Late spermatids [nTPM]":"6.7","Single Cell Type RNA - Leydig cells [nTPM]":"25.1","Single Cell Type RNA - Macrophages [nTPM]":"3.9","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"3.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.2","Single Cell Type RNA - Paneth cells [nTPM]":"3.9","Single Cell Type RNA - Peritubular cells [nTPM]":"70.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"25.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.8","Single Cell Type RNA - Spermatocytes [nTPM]":"4.1","Single Cell Type RNA - Spermatogonia [nTPM]":"2.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.2","Single Cell Type RNA - T-cells [nTPM]":"2.6","Single Cell Type RNA - Theca cells [nTPM]":"1.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.5","Single Cell Type RNA - Urothelial cells [nTPM]":"1.7"},{"Gene":"EPS8L3","Gene synonym":["FLJ21522","MGC16817"],"Ensembl":"ENSG00000198758","Gene description":"EPS8 like 3","Uniprot":["Q8TE67"],"Chromosome":"1","Position":"109750080-109764027","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Hypotrichosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"gallbladder":"35.7","intestine":"142.1","stomach 1":"50.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"254.4","Gastric mucus-secreting cells":"80.5","Intestinal goblet cells":"103.4","Late spermatids":"144.6","Paneth cells":"257.8","Proximal enterocytes":"285.3","Undifferentiated cells":"112.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"colorectal cancer":"52.5","pancreatic cancer":"29.7","stomach cancer":"26.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"15.6","CAPAN-2":"14.4","Hep G2":"36.2","OE19":"67.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030998"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA030998":"AB_2673691"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.13e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-3"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.52e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.82e-4"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"10.8","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"1.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"77.1","Tissue RNA - duodenum [nTPM]":"141.8","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"35.7","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.7","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"77.1","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"142.1","Tissue RNA - smooth muscle [nTPM]":"2.9","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"50.7","Tissue RNA - testis [nTPM]":"2.5","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"1.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"1.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"15.6","Cell RNA - CAPAN-2 [nTPM]":"14.4","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"5.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"36.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"67.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"0.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"254.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"11.6","Single Cell Type RNA - Early spermatids [nTPM]":"28.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"51.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"80.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.0","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"103.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"144.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"44.5","Single Cell Type RNA - Paneth cells [nTPM]":"257.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"285.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"112.6","Single Cell Type RNA - Urothelial cells [nTPM]":"1.8"},{"Gene":"ERCC2","Gene synonym":["EM9","MAG","MGC102762","MGC126218","MGC126219","XPD"],"Ensembl":"ENSG00000104884","Gene description":"ERCC excision repair 2, TFIIH core complex helicase subunit","Uniprot":["P18074"],"Chromosome":"19","Position":"45349837-45370918","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Chromosome partition","DNA damage","DNA repair","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Cancer-related genes","Cataract","Cockayne syndrome","Deafness","Disease variant","Dwarfism","Ichthyosis","Xeroderma pigmentosum"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"34.1","Spermatocytes":"30.5","Theca cells":"29.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005375","HPA038057","HPA069266"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB005375":"AB_2100152","HPA038057":"AB_2675810","HPA069266":"AB_2686104"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.26e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.8","Tissue RNA - adrenal gland [nTPM]":"13.0","Tissue RNA - amygdala [nTPM]":"10.5","Tissue RNA - appendix [nTPM]":"6.9","Tissue RNA - basal ganglia [nTPM]":"10.3","Tissue RNA - bone marrow [nTPM]":"4.8","Tissue RNA - breast [nTPM]":"6.5","Tissue RNA - cerebellum [nTPM]":"8.4","Tissue RNA - cerebral cortex [nTPM]":"11.7","Tissue RNA - cervix [nTPM]":"7.5","Tissue RNA - choroid plexus [nTPM]":"8.4","Tissue RNA - colon [nTPM]":"7.5","Tissue RNA - duodenum [nTPM]":"4.9","Tissue RNA - endometrium 1 [nTPM]":"9.7","Tissue RNA - epididymis [nTPM]":"3.2","Tissue RNA - esophagus [nTPM]":"6.3","Tissue RNA - fallopian tube [nTPM]":"8.0","Tissue RNA - gallbladder [nTPM]":"4.1","Tissue RNA - heart muscle [nTPM]":"7.0","Tissue RNA - hippocampal formation [nTPM]":"10.8","Tissue RNA - hypothalamus [nTPM]":"9.3","Tissue RNA - kidney [nTPM]":"7.6","Tissue RNA - liver [nTPM]":"9.0","Tissue RNA - lung [nTPM]":"5.8","Tissue RNA - lymph node [nTPM]":"5.8","Tissue RNA - medulla oblongata [nTPM]":"10.6","Tissue RNA - midbrain [nTPM]":"9.9","Tissue RNA - ovary [nTPM]":"7.8","Tissue RNA - pancreas [nTPM]":"7.7","Tissue RNA - parathyroid gland [nTPM]":"7.7","Tissue RNA - pituitary gland [nTPM]":"9.7","Tissue RNA - placenta [nTPM]":"4.5","Tissue RNA - pons [nTPM]":"9.6","Tissue RNA - prostate [nTPM]":"6.7","Tissue RNA - rectum [nTPM]":"4.0","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"7.3","Tissue RNA - seminal vesicle [nTPM]":"6.7","Tissue RNA - skeletal muscle [nTPM]":"11.7","Tissue RNA - skin 1 [nTPM]":"7.2","Tissue RNA - small intestine [nTPM]":"6.6","Tissue RNA - smooth muscle [nTPM]":"6.9","Tissue RNA - spinal cord [nTPM]":"8.1","Tissue RNA - spleen [nTPM]":"8.1","Tissue RNA - stomach 1 [nTPM]":"7.5","Tissue RNA - testis [nTPM]":"13.9","Tissue RNA - thalamus [nTPM]":"10.1","Tissue RNA - thymus [nTPM]":"5.3","Tissue RNA - thyroid gland [nTPM]":"8.4","Tissue RNA - tongue [nTPM]":"6.3","Tissue RNA - tonsil [nTPM]":"5.2","Tissue RNA - urinary bladder [nTPM]":"7.5","Tissue RNA - vagina [nTPM]":"5.9","Tissue RNA - white matter [nTPM]":"8.9","Cell RNA - A-431 [nTPM]":"28.0","Cell RNA - A549 [nTPM]":"13.3","Cell RNA - AF22 [nTPM]":"27.1","Cell RNA - AN3-CA [nTPM]":"38.4","Cell RNA - ASC diff [nTPM]":"16.3","Cell RNA - ASC TERT1 [nTPM]":"19.4","Cell RNA - BEWO [nTPM]":"15.2","Cell RNA - BJ [nTPM]":"38.8","Cell RNA - BJ hTERT+ [nTPM]":"27.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"50.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"40.2","Cell RNA - CACO-2 [nTPM]":"32.6","Cell RNA - CAPAN-2 [nTPM]":"18.6","Cell RNA - Daudi [nTPM]":"10.0","Cell RNA - EFO-21 [nTPM]":"21.6","Cell RNA - fHDF\/TERT166 [nTPM]":"39.9","Cell RNA - GAMG [nTPM]":"19.1","Cell RNA - HaCaT [nTPM]":"14.0","Cell RNA - HAP1 [nTPM]":"19.1","Cell RNA - HBEC3-KT [nTPM]":"32.9","Cell RNA - HBF TERT88 [nTPM]":"18.5","Cell RNA - HDLM-2 [nTPM]":"24.4","Cell RNA - HEK 293 [nTPM]":"31.8","Cell RNA - HEL [nTPM]":"16.9","Cell RNA - HeLa [nTPM]":"26.8","Cell RNA - Hep G2 [nTPM]":"35.4","Cell RNA - HHSteC [nTPM]":"33.3","Cell RNA - HL-60 [nTPM]":"27.1","Cell RNA - HMC-1 [nTPM]":"28.4","Cell RNA - HSkMC [nTPM]":"22.4","Cell RNA - hTCEpi [nTPM]":"5.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"55.8","Cell RNA - hTERT-HME1 [nTPM]":"31.9","Cell RNA - hTERT-RPE1 [nTPM]":"28.2","Cell RNA - HUVEC TERT2 [nTPM]":"29.1","Cell RNA - JURKAT [nTPM]":"28.8","Cell RNA - K-562 [nTPM]":"41.8","Cell RNA - Karpas-707 [nTPM]":"10.9","Cell RNA - LHCN-M2 [nTPM]":"34.8","Cell RNA - MCF7 [nTPM]":"14.7","Cell RNA - MOLT-4 [nTPM]":"16.1","Cell RNA - NB-4 [nTPM]":"17.9","Cell RNA - NTERA-2 [nTPM]":"12.7","Cell RNA - OE19 [nTPM]":"27.2","Cell RNA - PC-3 [nTPM]":"24.6","Cell RNA - REH [nTPM]":"30.3","Cell RNA - RH-30 [nTPM]":"19.4","Cell RNA - RPMI-8226 [nTPM]":"8.3","Cell RNA - RPTEC TERT1 [nTPM]":"14.0","Cell RNA - RT4 [nTPM]":"24.9","Cell RNA - SCLC-21H [nTPM]":"15.8","Cell RNA - SH-SY5Y [nTPM]":"17.1","Cell RNA - SiHa [nTPM]":"34.2","Cell RNA - SK-BR-3 [nTPM]":"23.9","Cell RNA - SK-MEL-30 [nTPM]":"13.6","Cell RNA - SuSa [nTPM]":"20.6","Cell RNA - T-47d [nTPM]":"22.8","Cell RNA - THP-1 [nTPM]":"35.4","Cell RNA - TIME [nTPM]":"37.9","Cell RNA - U-138 MG [nTPM]":"46.4","Cell RNA - U-2 OS [nTPM]":"25.3","Cell RNA - U-2197 [nTPM]":"19.9","Cell RNA - U-251 MG [nTPM]":"88.0","Cell RNA - U-266\/70 [nTPM]":"24.9","Cell RNA - U-266\/84 [nTPM]":"15.8","Cell RNA - U-698 [nTPM]":"14.2","Cell RNA - U-87 MG [nTPM]":"13.8","Cell RNA - U-937 [nTPM]":"16.4","Cell RNA - WM-115 [nTPM]":"21.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"17.2","Blood RNA - eosinophil [nTPM]":"6.5","Blood RNA - gdT-cell [nTPM]":"9.1","Blood RNA - intermediate monocyte [nTPM]":"18.0","Blood RNA - MAIT T-cell [nTPM]":"11.9","Blood RNA - memory B-cell [nTPM]":"9.1","Blood RNA - memory CD4 T-cell [nTPM]":"8.9","Blood RNA - memory CD8 T-cell [nTPM]":"8.9","Blood RNA - myeloid DC [nTPM]":"21.8","Blood RNA - naive B-cell [nTPM]":"6.5","Blood RNA - naive CD4 T-cell [nTPM]":"8.2","Blood RNA - naive CD8 T-cell [nTPM]":"8.7","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"15.6","Blood RNA - non-classical monocyte [nTPM]":"14.9","Blood RNA - plasmacytoid DC [nTPM]":"10.4","Blood RNA - T-reg [nTPM]":"9.8","Blood RNA - total PBMC [nTPM]":"12.1","Brain RNA - amygdala [nTPM]":"10.5","Brain RNA - basal ganglia [nTPM]":"10.3","Brain RNA - cerebellum [nTPM]":"8.4","Brain RNA - cerebral cortex [nTPM]":"11.7","Brain RNA - hippocampal formation [nTPM]":"10.8","Brain RNA - hypothalamus [nTPM]":"9.3","Brain RNA - medulla oblongata [nTPM]":"10.6","Brain RNA - midbrain [nTPM]":"9.9","Brain RNA - pons [nTPM]":"9.6","Brain RNA - spinal cord [nTPM]":"8.1","Brain RNA - thalamus [nTPM]":"10.1","Brain RNA - white matter [nTPM]":"8.9","Single Cell Type RNA - Adipocytes [nTPM]":"4.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.4","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"5.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"8.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.5","Single Cell Type RNA - dendritic cells [nTPM]":"4.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"10.7","Single Cell Type RNA - Early spermatids [nTPM]":"4.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.5","Single Cell Type RNA - Endothelial cells [nTPM]":"5.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"5.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.1","Single Cell Type RNA - Fibroblasts [nTPM]":"6.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"34.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"12.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.5","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"8.2","Single Cell Type RNA - Langerhans cells [nTPM]":"4.2","Single Cell Type RNA - Late spermatids [nTPM]":"2.8","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"6.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"4.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.1","Single Cell Type RNA - Paneth cells [nTPM]":"3.1","Single Cell Type RNA - Peritubular cells [nTPM]":"7.9","Single Cell Type RNA - Plasma cells [nTPM]":"7.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.9","Single Cell Type RNA - Spermatocytes [nTPM]":"30.5","Single Cell Type RNA - Spermatogonia [nTPM]":"13.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.8","Single Cell Type RNA - T-cells [nTPM]":"4.7","Single Cell Type RNA - Theca cells [nTPM]":"29.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.8","Single Cell Type RNA - Urothelial cells [nTPM]":"3.2"},{"Gene":"ERCC3","Gene synonym":["BTF2","RAD25","XPB"],"Ensembl":"ENSG00000163161","Gene description":"ERCC excision repair 3, TFIIH core complex helicase subunit","Uniprot":["P19447"],"Chromosome":"2","Position":"127257290-127294166","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Cancer-related genes","Cockayne syndrome","Deafness","Disease variant","Dwarfism","Ichthyosis","Xeroderma pigmentosum"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037153","HPA046077"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB037153":"AB_796181","HPA046077":"AB_2679527"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.62e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.30e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-2"},"Tissue RNA - adipose tissue [nTPM]":"24.4","Tissue RNA - adrenal gland [nTPM]":"25.9","Tissue RNA - amygdala [nTPM]":"15.0","Tissue RNA - appendix [nTPM]":"14.5","Tissue RNA - basal ganglia [nTPM]":"16.0","Tissue RNA - bone marrow [nTPM]":"19.8","Tissue RNA - breast [nTPM]":"24.4","Tissue RNA - cerebellum [nTPM]":"15.1","Tissue RNA - cerebral cortex [nTPM]":"16.5","Tissue RNA - cervix [nTPM]":"32.2","Tissue RNA - choroid plexus [nTPM]":"19.6","Tissue RNA - colon [nTPM]":"28.9","Tissue RNA - duodenum [nTPM]":"9.6","Tissue RNA - endometrium 1 [nTPM]":"27.0","Tissue RNA - epididymis [nTPM]":"11.6","Tissue RNA - esophagus [nTPM]":"22.7","Tissue RNA - fallopian tube [nTPM]":"28.9","Tissue RNA - gallbladder [nTPM]":"14.2","Tissue RNA - heart muscle [nTPM]":"23.4","Tissue RNA - hippocampal formation [nTPM]":"16.6","Tissue RNA - hypothalamus [nTPM]":"14.9","Tissue RNA - kidney [nTPM]":"22.8","Tissue RNA - liver [nTPM]":"22.2","Tissue RNA - lung [nTPM]":"22.1","Tissue RNA - lymph node [nTPM]":"21.6","Tissue RNA - medulla oblongata [nTPM]":"15.7","Tissue RNA - midbrain [nTPM]":"14.8","Tissue RNA - ovary [nTPM]":"29.5","Tissue RNA - pancreas [nTPM]":"23.8","Tissue RNA - parathyroid gland [nTPM]":"26.3","Tissue RNA - pituitary gland [nTPM]":"33.8","Tissue RNA - placenta [nTPM]":"13.6","Tissue RNA - pons [nTPM]":"16.0","Tissue RNA - prostate [nTPM]":"27.4","Tissue RNA - rectum [nTPM]":"13.8","Tissue RNA - retina [nTPM]":"4.4","Tissue RNA - salivary gland [nTPM]":"23.2","Tissue RNA - seminal vesicle [nTPM]":"16.8","Tissue RNA - skeletal muscle [nTPM]":"35.3","Tissue RNA - skin 1 [nTPM]":"27.7","Tissue RNA - small intestine [nTPM]":"24.3","Tissue RNA - smooth muscle [nTPM]":"21.5","Tissue RNA - spinal cord [nTPM]":"15.1","Tissue RNA - spleen [nTPM]":"32.6","Tissue RNA - stomach 1 [nTPM]":"23.7","Tissue RNA - testis [nTPM]":"29.8","Tissue RNA - thalamus [nTPM]":"15.6","Tissue RNA - thymus [nTPM]":"26.6","Tissue RNA - thyroid gland [nTPM]":"25.0","Tissue RNA - tongue [nTPM]":"25.6","Tissue RNA - tonsil [nTPM]":"22.4","Tissue RNA - urinary bladder [nTPM]":"27.2","Tissue RNA - vagina [nTPM]":"26.4","Tissue RNA - white matter [nTPM]":"15.2","Cell RNA - A-431 [nTPM]":"45.9","Cell RNA - A549 [nTPM]":"30.8","Cell RNA - AF22 [nTPM]":"37.8","Cell RNA - AN3-CA [nTPM]":"40.6","Cell RNA - ASC diff [nTPM]":"40.6","Cell RNA - ASC TERT1 [nTPM]":"27.8","Cell RNA - BEWO [nTPM]":"46.4","Cell RNA - BJ [nTPM]":"41.3","Cell RNA - BJ hTERT+ [nTPM]":"52.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"65.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"62.5","Cell RNA - CACO-2 [nTPM]":"48.1","Cell RNA - CAPAN-2 [nTPM]":"32.9","Cell RNA - Daudi [nTPM]":"34.5","Cell RNA - EFO-21 [nTPM]":"33.2","Cell RNA - fHDF\/TERT166 [nTPM]":"37.8","Cell RNA - GAMG [nTPM]":"41.7","Cell RNA - HaCaT [nTPM]":"40.2","Cell RNA - HAP1 [nTPM]":"57.7","Cell RNA - HBEC3-KT [nTPM]":"43.3","Cell RNA - HBF TERT88 [nTPM]":"56.1","Cell RNA - HDLM-2 [nTPM]":"54.4","Cell RNA - HEK 293 [nTPM]":"51.4","Cell RNA - HEL [nTPM]":"43.6","Cell RNA - HeLa [nTPM]":"35.8","Cell RNA - Hep G2 [nTPM]":"51.0","Cell RNA - HHSteC [nTPM]":"30.5","Cell RNA - HL-60 [nTPM]":"38.1","Cell RNA - HMC-1 [nTPM]":"45.4","Cell RNA - HSkMC [nTPM]":"28.9","Cell RNA - hTCEpi [nTPM]":"39.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"75.7","Cell RNA - hTERT-HME1 [nTPM]":"32.4","Cell RNA - hTERT-RPE1 [nTPM]":"41.5","Cell RNA - HUVEC TERT2 [nTPM]":"42.4","Cell RNA - JURKAT [nTPM]":"44.3","Cell RNA - K-562 [nTPM]":"43.0","Cell RNA - Karpas-707 [nTPM]":"22.1","Cell RNA - LHCN-M2 [nTPM]":"41.7","Cell RNA - MCF7 [nTPM]":"45.1","Cell RNA - MOLT-4 [nTPM]":"54.8","Cell RNA - NB-4 [nTPM]":"42.2","Cell RNA - NTERA-2 [nTPM]":"55.0","Cell RNA - OE19 [nTPM]":"29.2","Cell RNA - PC-3 [nTPM]":"47.3","Cell RNA - REH [nTPM]":"44.5","Cell RNA - RH-30 [nTPM]":"42.7","Cell RNA - RPMI-8226 [nTPM]":"28.8","Cell RNA - RPTEC TERT1 [nTPM]":"36.4","Cell RNA - RT4 [nTPM]":"42.2","Cell RNA - SCLC-21H [nTPM]":"45.2","Cell RNA - SH-SY5Y [nTPM]":"49.2","Cell RNA - SiHa [nTPM]":"35.3","Cell RNA - SK-BR-3 [nTPM]":"52.6","Cell RNA - SK-MEL-30 [nTPM]":"55.0","Cell RNA - SuSa [nTPM]":"42.4","Cell RNA - T-47d [nTPM]":"28.7","Cell RNA - THP-1 [nTPM]":"43.0","Cell RNA - TIME [nTPM]":"34.1","Cell RNA - U-138 MG [nTPM]":"39.2","Cell RNA - U-2 OS [nTPM]":"45.2","Cell RNA - U-2197 [nTPM]":"35.8","Cell RNA - U-251 MG [nTPM]":"49.7","Cell RNA - U-266\/70 [nTPM]":"39.2","Cell RNA - U-266\/84 [nTPM]":"81.5","Cell RNA - U-698 [nTPM]":"54.0","Cell RNA - U-87 MG [nTPM]":"34.3","Cell RNA - U-937 [nTPM]":"18.0","Cell RNA - WM-115 [nTPM]":"42.8","Blood RNA - basophil [nTPM]":"8.0","Blood RNA - classical monocyte [nTPM]":"11.5","Blood RNA - eosinophil [nTPM]":"8.8","Blood RNA - gdT-cell [nTPM]":"18.2","Blood RNA - intermediate monocyte [nTPM]":"12.0","Blood RNA - MAIT T-cell [nTPM]":"18.4","Blood RNA - memory B-cell [nTPM]":"13.7","Blood RNA - memory CD4 T-cell [nTPM]":"13.1","Blood RNA - memory CD8 T-cell [nTPM]":"15.7","Blood RNA - myeloid DC [nTPM]":"16.9","Blood RNA - naive B-cell [nTPM]":"12.7","Blood RNA - naive CD4 T-cell [nTPM]":"17.7","Blood RNA - naive CD8 T-cell [nTPM]":"12.2","Blood RNA - neutrophil [nTPM]":"3.5","Blood RNA - NK-cell [nTPM]":"25.0","Blood RNA - non-classical monocyte [nTPM]":"9.9","Blood RNA - plasmacytoid DC [nTPM]":"13.6","Blood RNA - T-reg [nTPM]":"20.5","Blood RNA - total PBMC [nTPM]":"15.5","Brain RNA - amygdala [nTPM]":"15.0","Brain RNA - basal ganglia [nTPM]":"16.0","Brain RNA - cerebellum [nTPM]":"15.1","Brain RNA - cerebral cortex [nTPM]":"16.5","Brain RNA - hippocampal formation [nTPM]":"16.6","Brain RNA - hypothalamus [nTPM]":"14.9","Brain RNA - medulla oblongata [nTPM]":"15.7","Brain RNA - midbrain [nTPM]":"14.8","Brain RNA - pons [nTPM]":"16.0","Brain RNA - spinal cord [nTPM]":"15.1","Brain RNA - thalamus [nTPM]":"15.6","Brain RNA - white matter [nTPM]":"15.2","Single Cell Type RNA - Adipocytes [nTPM]":"12.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.6","Single Cell Type RNA - Astrocytes [nTPM]":"24.8","Single Cell Type RNA - B-cells [nTPM]":"17.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"20.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.1","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"25.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.6","Single Cell Type RNA - dendritic cells [nTPM]":"18.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.7","Single Cell Type RNA - Early spermatids [nTPM]":"9.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.9","Single Cell Type RNA - Endothelial cells [nTPM]":"12.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.1","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.2","Single Cell Type RNA - Fibroblasts [nTPM]":"16.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.1","Single Cell Type RNA - granulocytes [nTPM]":"10.1","Single Cell Type RNA - Granulosa cells [nTPM]":"17.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.4","Single Cell Type RNA - Hepatocytes [nTPM]":"8.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"23.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.0","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"12.5","Single Cell Type RNA - Langerhans cells [nTPM]":"7.6","Single Cell Type RNA - Late spermatids [nTPM]":"5.1","Single Cell Type RNA - Leydig cells [nTPM]":"16.4","Single Cell Type RNA - Macrophages [nTPM]":"10.7","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"12.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"22.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.5","Single Cell Type RNA - Paneth cells [nTPM]":"7.3","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"16.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"45.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.3","Single Cell Type RNA - Spermatocytes [nTPM]":"41.1","Single Cell Type RNA - Spermatogonia [nTPM]":"31.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.6","Single Cell Type RNA - T-cells [nTPM]":"15.7","Single Cell Type RNA - Theca cells [nTPM]":"12.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.6","Single Cell Type RNA - Urothelial cells [nTPM]":"8.5"},{"Gene":"ERCC6","Gene synonym":["ARMD5","CKN2","CSB","RAD26"],"Ensembl":"ENSG00000225830","Gene description":"ERCC excision repair 6, chromatin remodeling factor","Uniprot":["P0DP91","Q03468"],"Chromosome":"10","Position":"49454168-49539538","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Neurogenesis","Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Age-related macular degeneration","Cancer-related genes","Cataract","Cockayne syndrome","Deafness","Disease variant","Dwarfism","Mental retardation","Premature ovarian failure","Xeroderma pigmentosum"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTERT-HME1":"53.8","hTERT-RPE1":"123.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA071297"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA071297":"AB_2732177"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.05e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.7","Tissue RNA - adrenal gland [nTPM]":"2.1","Tissue RNA - amygdala [nTPM]":"1.6","Tissue RNA - appendix [nTPM]":"1.9","Tissue RNA - basal ganglia [nTPM]":"1.5","Tissue RNA - bone marrow [nTPM]":"4.6","Tissue RNA - breast [nTPM]":"3.8","Tissue RNA - cerebellum [nTPM]":"3.0","Tissue RNA - cerebral cortex [nTPM]":"2.3","Tissue RNA - cervix [nTPM]":"3.1","Tissue RNA - choroid plexus [nTPM]":"7.7","Tissue RNA - colon [nTPM]":"2.4","Tissue RNA - duodenum [nTPM]":"2.0","Tissue RNA - endometrium 1 [nTPM]":"3.0","Tissue RNA - epididymis [nTPM]":"1.5","Tissue RNA - esophagus [nTPM]":"3.8","Tissue RNA - fallopian tube [nTPM]":"2.9","Tissue RNA - gallbladder [nTPM]":"2.7","Tissue RNA - heart muscle [nTPM]":"3.4","Tissue RNA - hippocampal formation [nTPM]":"1.2","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"3.2","Tissue RNA - liver [nTPM]":"3.3","Tissue RNA - lung [nTPM]":"2.7","Tissue RNA - lymph node [nTPM]":"2.9","Tissue RNA - medulla oblongata [nTPM]":"2.4","Tissue RNA - midbrain [nTPM]":"1.9","Tissue RNA - ovary [nTPM]":"4.5","Tissue RNA - pancreas [nTPM]":"3.1","Tissue RNA - parathyroid gland [nTPM]":"5.9","Tissue RNA - pituitary gland [nTPM]":"2.8","Tissue RNA - placenta [nTPM]":"3.4","Tissue RNA - pons [nTPM]":"2.1","Tissue RNA - prostate [nTPM]":"3.3","Tissue RNA - rectum [nTPM]":"2.7","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"3.2","Tissue RNA - seminal vesicle [nTPM]":"2.2","Tissue RNA - skeletal muscle [nTPM]":"3.5","Tissue RNA - skin 1 [nTPM]":"4.6","Tissue RNA - small intestine [nTPM]":"2.5","Tissue RNA - smooth muscle [nTPM]":"2.3","Tissue RNA - spinal cord [nTPM]":"2.2","Tissue RNA - spleen [nTPM]":"2.9","Tissue RNA - stomach 1 [nTPM]":"2.4","Tissue RNA - testis [nTPM]":"3.1","Tissue RNA - thalamus [nTPM]":"2.1","Tissue RNA - thymus [nTPM]":"3.3","Tissue RNA - thyroid gland [nTPM]":"5.1","Tissue RNA - tongue [nTPM]":"3.6","Tissue RNA - tonsil [nTPM]":"3.4","Tissue RNA - urinary bladder [nTPM]":"2.6","Tissue RNA - vagina [nTPM]":"3.3","Tissue RNA - white matter [nTPM]":"1.9","Cell RNA - A-431 [nTPM]":"11.2","Cell RNA - A549 [nTPM]":"5.5","Cell RNA - AF22 [nTPM]":"4.1","Cell RNA - AN3-CA [nTPM]":"2.1","Cell RNA - ASC diff [nTPM]":"6.6","Cell RNA - ASC TERT1 [nTPM]":"10.5","Cell RNA - BEWO [nTPM]":"3.4","Cell RNA - BJ [nTPM]":"21.2","Cell RNA - BJ hTERT+ [nTPM]":"27.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.9","Cell RNA - CACO-2 [nTPM]":"6.2","Cell RNA - CAPAN-2 [nTPM]":"5.6","Cell RNA - Daudi [nTPM]":"4.9","Cell RNA - EFO-21 [nTPM]":"3.7","Cell RNA - fHDF\/TERT166 [nTPM]":"18.7","Cell RNA - GAMG [nTPM]":"6.7","Cell RNA - HaCaT [nTPM]":"9.5","Cell RNA - HAP1 [nTPM]":"6.3","Cell RNA - HBEC3-KT [nTPM]":"16.6","Cell RNA - HBF TERT88 [nTPM]":"13.5","Cell RNA - HDLM-2 [nTPM]":"8.4","Cell RNA - HEK 293 [nTPM]":"4.1","Cell RNA - HEL [nTPM]":"3.9","Cell RNA - HeLa [nTPM]":"21.7","Cell RNA - Hep G2 [nTPM]":"3.4","Cell RNA - HHSteC [nTPM]":"3.9","Cell RNA - HL-60 [nTPM]":"5.0","Cell RNA - HMC-1 [nTPM]":"3.7","Cell RNA - HSkMC [nTPM]":"4.3","Cell RNA - hTCEpi [nTPM]":"17.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.9","Cell RNA - hTERT-HME1 [nTPM]":"53.8","Cell RNA - hTERT-RPE1 [nTPM]":"123.4","Cell RNA - HUVEC TERT2 [nTPM]":"19.8","Cell RNA - JURKAT [nTPM]":"2.9","Cell RNA - K-562 [nTPM]":"6.8","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"16.8","Cell RNA - MCF7 [nTPM]":"8.3","Cell RNA - MOLT-4 [nTPM]":"3.4","Cell RNA - NB-4 [nTPM]":"2.0","Cell RNA - NTERA-2 [nTPM]":"4.0","Cell RNA - OE19 [nTPM]":"3.5","Cell RNA - PC-3 [nTPM]":"10.2","Cell RNA - REH [nTPM]":"2.3","Cell RNA - RH-30 [nTPM]":"5.8","Cell RNA - RPMI-8226 [nTPM]":"2.6","Cell RNA - RPTEC TERT1 [nTPM]":"4.1","Cell RNA - RT4 [nTPM]":"7.1","Cell RNA - SCLC-21H [nTPM]":"5.9","Cell RNA - SH-SY5Y [nTPM]":"4.7","Cell RNA - SiHa [nTPM]":"15.4","Cell RNA - SK-BR-3 [nTPM]":"3.6","Cell RNA - SK-MEL-30 [nTPM]":"8.2","Cell RNA - SuSa [nTPM]":"9.4","Cell RNA - T-47d [nTPM]":"7.1","Cell RNA - THP-1 [nTPM]":"2.7","Cell RNA - TIME [nTPM]":"38.9","Cell RNA - U-138 MG [nTPM]":"7.0","Cell RNA - U-2 OS [nTPM]":"5.5","Cell RNA - U-2197 [nTPM]":"8.6","Cell RNA - U-251 MG [nTPM]":"5.2","Cell RNA - U-266\/70 [nTPM]":"3.3","Cell RNA - U-266\/84 [nTPM]":"4.5","Cell RNA - U-698 [nTPM]":"4.1","Cell RNA - U-87 MG [nTPM]":"7.3","Cell RNA - U-937 [nTPM]":"5.0","Cell RNA - WM-115 [nTPM]":"5.1","Blood RNA - basophil [nTPM]":"13.1","Blood RNA - classical monocyte [nTPM]":"3.0","Blood RNA - eosinophil [nTPM]":"7.5","Blood RNA - gdT-cell [nTPM]":"4.1","Blood RNA - intermediate monocyte [nTPM]":"2.6","Blood RNA - MAIT T-cell [nTPM]":"3.0","Blood RNA - memory B-cell [nTPM]":"6.8","Blood RNA - memory CD4 T-cell [nTPM]":"2.3","Blood RNA - memory CD8 T-cell [nTPM]":"2.2","Blood RNA - myeloid DC [nTPM]":"3.9","Blood RNA - naive B-cell [nTPM]":"5.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"7.2","Blood RNA - NK-cell [nTPM]":"1.2","Blood RNA - non-classical monocyte [nTPM]":"5.3","Blood RNA - plasmacytoid DC [nTPM]":"2.2","Blood RNA - T-reg [nTPM]":"3.1","Blood RNA - total PBMC [nTPM]":"1.8","Brain RNA - amygdala [nTPM]":"1.6","Brain RNA - basal ganglia [nTPM]":"1.5","Brain RNA - cerebellum [nTPM]":"3.0","Brain RNA - cerebral cortex [nTPM]":"2.3","Brain RNA - hippocampal formation [nTPM]":"1.2","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"2.4","Brain RNA - midbrain [nTPM]":"1.9","Brain RNA - pons [nTPM]":"2.1","Brain RNA - spinal cord [nTPM]":"2.2","Brain RNA - thalamus [nTPM]":"2.1","Brain RNA - white matter [nTPM]":"1.9","Single Cell Type RNA - Adipocytes [nTPM]":"6.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.2","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"6.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"8.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - dendritic cells [nTPM]":"10.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.2","Single Cell Type RNA - Early spermatids [nTPM]":"11.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.7","Single Cell Type RNA - Endothelial cells [nTPM]":"5.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"24.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.1","Single Cell Type RNA - Fibroblasts [nTPM]":"4.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.1","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"8.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"4.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.4","Single Cell Type RNA - Langerhans cells [nTPM]":"2.6","Single Cell Type RNA - Late spermatids [nTPM]":"15.3","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"8.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"11.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.2","Single Cell Type RNA - Paneth cells [nTPM]":"2.6","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"3.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.2","Single Cell Type RNA - Spermatocytes [nTPM]":"5.3","Single Cell Type RNA - Spermatogonia [nTPM]":"5.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.8","Single Cell Type RNA - T-cells [nTPM]":"7.4","Single Cell Type RNA - Theca cells [nTPM]":"11.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.8","Single Cell Type RNA - Urothelial cells [nTPM]":"1.9"},{"Gene":"ERCC8","Gene synonym":["CKN1","CSA"],"Ensembl":"ENSG00000049167","Gene description":"ERCC excision repair 8, CSA ubiquitin ligase complex subunit","Uniprot":["Q13216"],"Chromosome":"5","Position":"60866454-60945073","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":["Cockayne syndrome","Deafness","Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"47.3","Excitatory neurons":"51.8","Inhibitory neurons":"47.9","Oligodendrocyte precursor cells":"44.2","Oligodendrocytes":"57.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029328"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA029328":"AB_2673000"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.4","Tissue RNA - adrenal gland [nTPM]":"3.1","Tissue RNA - amygdala [nTPM]":"2.3","Tissue RNA - appendix [nTPM]":"1.6","Tissue RNA - basal ganglia [nTPM]":"2.4","Tissue RNA - bone marrow [nTPM]":"2.0","Tissue RNA - breast [nTPM]":"3.1","Tissue RNA - cerebellum [nTPM]":"3.1","Tissue RNA - cerebral cortex [nTPM]":"3.2","Tissue RNA - cervix [nTPM]":"2.5","Tissue RNA - choroid plexus [nTPM]":"1.5","Tissue RNA - colon [nTPM]":"2.6","Tissue RNA - duodenum [nTPM]":"1.7","Tissue RNA - endometrium 1 [nTPM]":"3.0","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"2.8","Tissue RNA - fallopian tube [nTPM]":"2.4","Tissue RNA - gallbladder [nTPM]":"1.9","Tissue RNA - heart muscle [nTPM]":"3.2","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"1.7","Tissue RNA - kidney [nTPM]":"4.0","Tissue RNA - liver [nTPM]":"3.2","Tissue RNA - lung [nTPM]":"2.2","Tissue RNA - lymph node [nTPM]":"1.6","Tissue RNA - medulla oblongata [nTPM]":"1.9","Tissue RNA - midbrain [nTPM]":"1.8","Tissue RNA - ovary [nTPM]":"2.7","Tissue RNA - pancreas [nTPM]":"2.7","Tissue RNA - parathyroid gland [nTPM]":"3.0","Tissue RNA - pituitary gland [nTPM]":"2.5","Tissue RNA - placenta [nTPM]":"2.1","Tissue RNA - pons [nTPM]":"2.1","Tissue RNA - prostate [nTPM]":"2.2","Tissue RNA - rectum [nTPM]":"2.4","Tissue RNA - retina [nTPM]":"2.7","Tissue RNA - salivary gland [nTPM]":"2.7","Tissue RNA - seminal vesicle [nTPM]":"2.1","Tissue RNA - skeletal muscle [nTPM]":"3.0","Tissue RNA - skin 1 [nTPM]":"2.4","Tissue RNA - small intestine [nTPM]":"2.2","Tissue RNA - smooth muscle [nTPM]":"2.3","Tissue RNA - spinal cord [nTPM]":"1.4","Tissue RNA - spleen [nTPM]":"2.6","Tissue RNA - stomach 1 [nTPM]":"2.5","Tissue RNA - testis [nTPM]":"4.1","Tissue RNA - thalamus [nTPM]":"2.0","Tissue RNA - thymus [nTPM]":"2.8","Tissue RNA - thyroid gland [nTPM]":"2.9","Tissue RNA - tongue [nTPM]":"2.9","Tissue RNA - tonsil [nTPM]":"2.2","Tissue RNA - urinary bladder [nTPM]":"2.5","Tissue RNA - vagina [nTPM]":"2.6","Tissue RNA - white matter [nTPM]":"2.9","Cell RNA - A-431 [nTPM]":"4.8","Cell RNA - A549 [nTPM]":"4.9","Cell RNA - AF22 [nTPM]":"7.3","Cell RNA - AN3-CA [nTPM]":"9.5","Cell RNA - ASC diff [nTPM]":"6.0","Cell RNA - ASC TERT1 [nTPM]":"4.2","Cell RNA - BEWO [nTPM]":"8.2","Cell RNA - BJ [nTPM]":"7.6","Cell RNA - BJ hTERT+ [nTPM]":"6.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.2","Cell RNA - CACO-2 [nTPM]":"6.9","Cell RNA - CAPAN-2 [nTPM]":"8.6","Cell RNA - Daudi [nTPM]":"7.3","Cell RNA - EFO-21 [nTPM]":"9.4","Cell RNA - fHDF\/TERT166 [nTPM]":"4.2","Cell RNA - GAMG [nTPM]":"14.4","Cell RNA - HaCaT [nTPM]":"4.0","Cell RNA - HAP1 [nTPM]":"10.6","Cell RNA - HBEC3-KT [nTPM]":"7.4","Cell RNA - HBF TERT88 [nTPM]":"11.1","Cell RNA - HDLM-2 [nTPM]":"7.6","Cell RNA - HEK 293 [nTPM]":"6.0","Cell RNA - HEL [nTPM]":"5.3","Cell RNA - HeLa [nTPM]":"7.3","Cell RNA - Hep G2 [nTPM]":"7.7","Cell RNA - HHSteC [nTPM]":"5.0","Cell RNA - HL-60 [nTPM]":"4.9","Cell RNA - HMC-1 [nTPM]":"4.5","Cell RNA - HSkMC [nTPM]":"6.5","Cell RNA - hTCEpi [nTPM]":"6.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.1","Cell RNA - hTERT-HME1 [nTPM]":"7.5","Cell RNA - hTERT-RPE1 [nTPM]":"3.3","Cell RNA - HUVEC TERT2 [nTPM]":"9.9","Cell RNA - JURKAT [nTPM]":"8.8","Cell RNA - K-562 [nTPM]":"8.0","Cell RNA - Karpas-707 [nTPM]":"4.2","Cell RNA - LHCN-M2 [nTPM]":"5.2","Cell RNA - MCF7 [nTPM]":"8.1","Cell RNA - MOLT-4 [nTPM]":"6.9","Cell RNA - NB-4 [nTPM]":"8.0","Cell RNA - NTERA-2 [nTPM]":"6.5","Cell RNA - OE19 [nTPM]":"2.8","Cell RNA - PC-3 [nTPM]":"3.1","Cell RNA - REH [nTPM]":"11.0","Cell RNA - RH-30 [nTPM]":"9.6","Cell RNA - RPMI-8226 [nTPM]":"9.1","Cell RNA - RPTEC TERT1 [nTPM]":"4.7","Cell RNA - RT4 [nTPM]":"5.9","Cell RNA - SCLC-21H [nTPM]":"6.1","Cell RNA - SH-SY5Y [nTPM]":"11.3","Cell RNA - SiHa [nTPM]":"8.6","Cell RNA - SK-BR-3 [nTPM]":"3.6","Cell RNA - SK-MEL-30 [nTPM]":"6.5","Cell RNA - SuSa [nTPM]":"7.6","Cell RNA - T-47d [nTPM]":"11.2","Cell RNA - THP-1 [nTPM]":"3.6","Cell RNA - TIME [nTPM]":"3.8","Cell RNA - U-138 MG [nTPM]":"3.8","Cell RNA - U-2 OS [nTPM]":"7.4","Cell RNA - U-2197 [nTPM]":"7.6","Cell RNA - U-251 MG [nTPM]":"10.1","Cell RNA - U-266\/70 [nTPM]":"5.5","Cell RNA - U-266\/84 [nTPM]":"11.9","Cell RNA - U-698 [nTPM]":"12.7","Cell RNA - U-87 MG [nTPM]":"5.9","Cell RNA - U-937 [nTPM]":"10.1","Cell RNA - WM-115 [nTPM]":"8.3","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"4.2","Blood RNA - eosinophil [nTPM]":"0.9","Blood RNA - gdT-cell [nTPM]":"3.1","Blood RNA - intermediate monocyte [nTPM]":"3.4","Blood RNA - MAIT T-cell [nTPM]":"2.5","Blood RNA - memory B-cell [nTPM]":"2.7","Blood RNA - memory CD4 T-cell [nTPM]":"2.4","Blood RNA - memory CD8 T-cell [nTPM]":"2.8","Blood RNA - myeloid DC [nTPM]":"7.1","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"2.8","Blood RNA - naive CD8 T-cell [nTPM]":"3.2","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"2.2","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"3.5","Blood RNA - T-reg [nTPM]":"3.3","Blood RNA - total PBMC [nTPM]":"2.1","Brain RNA - amygdala [nTPM]":"2.3","Brain RNA - basal ganglia [nTPM]":"2.4","Brain RNA - cerebellum [nTPM]":"3.1","Brain RNA - cerebral cortex [nTPM]":"3.2","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"1.7","Brain RNA - medulla oblongata [nTPM]":"1.9","Brain RNA - midbrain [nTPM]":"1.8","Brain RNA - pons [nTPM]":"2.1","Brain RNA - spinal cord [nTPM]":"1.4","Brain RNA - thalamus [nTPM]":"2.0","Brain RNA - white matter [nTPM]":"2.9","Single Cell Type RNA - Adipocytes [nTPM]":"3.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.6","Single Cell Type RNA - Astrocytes [nTPM]":"28.4","Single Cell Type RNA - B-cells [nTPM]":"6.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"3.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.7","Single Cell Type RNA - dendritic cells [nTPM]":"4.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"5.0","Single Cell Type RNA - Early spermatids [nTPM]":"47.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.2","Single Cell Type RNA - Endothelial cells [nTPM]":"3.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"10.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"51.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.2","Single Cell Type RNA - Fibroblasts [nTPM]":"5.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.1","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"8.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"5.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"47.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.8","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"7.1","Single Cell Type RNA - Langerhans cells [nTPM]":"5.5","Single Cell Type RNA - Late spermatids [nTPM]":"11.2","Single Cell Type RNA - Leydig cells [nTPM]":"4.7","Single Cell Type RNA - Macrophages [nTPM]":"6.5","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"7.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"44.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"57.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.2","Single Cell Type RNA - Paneth cells [nTPM]":"2.2","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"11.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.6","Single Cell Type RNA - Spermatocytes [nTPM]":"22.5","Single Cell Type RNA - Spermatogonia [nTPM]":"9.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - T-cells [nTPM]":"6.5","Single Cell Type RNA - Theca cells [nTPM]":"8.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.4","Single Cell Type RNA - Urothelial cells [nTPM]":"3.5"},{"Gene":"FBN1","Gene synonym":["FBN","MASS","MFS1","OCTD","SGS","WMS"],"Ensembl":"ENSG00000166147","Gene description":"Fibrillin 1","Uniprot":["P35555"],"Chromosome":"15","Position":"48408313-48645721","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Heparin-binding","Hormone"],"Disease involvement":["Aortic aneurysm","Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"60.9","placenta":"76.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"132.4","Fibroblasts":"388.5","Leydig cells":"236.1","Oligodendrocytes":"218.7","Peritubular cells":"227.2","Skeletal myocytes":"139.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"215.1","ASC TERT1":"460.7","fHDF\/TERT166":"420.8","HSkMC":"251.3","hTERT-RPE1":"211.1","U-138 MG":"206.9","U-2197":"305.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002670","HPA017759","HPA021057","CAB058696","CAB068188"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"520000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB002670":null,"CAB058696":"AB_2665596","CAB068188":"AB_2665597","HPA017759":"AB_1848584","HPA021057":"AB_1848586"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.44e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.57e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.11e-4"},"Tissue RNA - adipose tissue [nTPM]":"60.9","Tissue RNA - adrenal gland [nTPM]":"4.4","Tissue RNA - amygdala [nTPM]":"1.4","Tissue RNA - appendix [nTPM]":"14.5","Tissue RNA - basal ganglia [nTPM]":"5.4","Tissue RNA - bone marrow [nTPM]":"3.4","Tissue RNA - breast [nTPM]":"13.7","Tissue RNA - cerebellum [nTPM]":"2.8","Tissue RNA - cerebral cortex [nTPM]":"2.8","Tissue RNA - cervix [nTPM]":"36.0","Tissue RNA - choroid plexus [nTPM]":"9.5","Tissue RNA - colon [nTPM]":"8.3","Tissue RNA - duodenum [nTPM]":"3.8","Tissue RNA - endometrium 1 [nTPM]":"15.2","Tissue RNA - epididymis [nTPM]":"6.3","Tissue RNA - esophagus [nTPM]":"12.6","Tissue RNA - fallopian tube [nTPM]":"12.2","Tissue RNA - gallbladder [nTPM]":"27.3","Tissue RNA - heart muscle [nTPM]":"23.5","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"2.0","Tissue RNA - kidney [nTPM]":"2.7","Tissue RNA - liver [nTPM]":"2.9","Tissue RNA - lung [nTPM]":"10.0","Tissue RNA - lymph node [nTPM]":"3.7","Tissue RNA - medulla oblongata [nTPM]":"5.2","Tissue RNA - midbrain [nTPM]":"6.0","Tissue RNA - ovary [nTPM]":"28.4","Tissue RNA - pancreas [nTPM]":"3.3","Tissue RNA - parathyroid gland [nTPM]":"3.0","Tissue RNA - pituitary gland [nTPM]":"2.5","Tissue RNA - placenta [nTPM]":"76.7","Tissue RNA - pons [nTPM]":"3.7","Tissue RNA - prostate [nTPM]":"8.0","Tissue RNA - rectum [nTPM]":"11.7","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"4.6","Tissue RNA - seminal vesicle [nTPM]":"13.2","Tissue RNA - skeletal muscle [nTPM]":"4.5","Tissue RNA - skin 1 [nTPM]":"5.7","Tissue RNA - small intestine [nTPM]":"6.6","Tissue RNA - smooth muscle [nTPM]":"35.7","Tissue RNA - spinal cord [nTPM]":"2.3","Tissue RNA - spleen [nTPM]":"6.4","Tissue RNA - stomach 1 [nTPM]":"6.0","Tissue RNA - testis [nTPM]":"7.1","Tissue RNA - thalamus [nTPM]":"4.7","Tissue RNA - thymus [nTPM]":"2.9","Tissue RNA - thyroid gland [nTPM]":"18.6","Tissue RNA - tongue [nTPM]":"21.2","Tissue RNA - tonsil [nTPM]":"3.5","Tissue RNA - urinary bladder [nTPM]":"18.8","Tissue RNA - vagina [nTPM]":"9.9","Tissue RNA - white matter [nTPM]":"5.0","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"5.2","Cell RNA - AF22 [nTPM]":"19.8","Cell RNA - AN3-CA [nTPM]":"22.4","Cell RNA - ASC diff [nTPM]":"215.1","Cell RNA - ASC TERT1 [nTPM]":"460.7","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"175.8","Cell RNA - BJ hTERT+ [nTPM]":"62.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"51.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"32.4","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"7.9","Cell RNA - fHDF\/TERT166 [nTPM]":"420.8","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.7","Cell RNA - HAP1 [nTPM]":"3.9","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"45.9","Cell RNA - HDLM-2 [nTPM]":"20.7","Cell RNA - HEK 293 [nTPM]":"1.2","Cell RNA - HEL [nTPM]":"2.0","Cell RNA - HeLa [nTPM]":"88.5","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"120.7","Cell RNA - HL-60 [nTPM]":"0.8","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"251.3","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"135.9","Cell RNA - hTERT-HME1 [nTPM]":"15.6","Cell RNA - hTERT-RPE1 [nTPM]":"211.1","Cell RNA - HUVEC TERT2 [nTPM]":"55.5","Cell RNA - JURKAT [nTPM]":"1.6","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"55.6","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"1.5","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"4.0","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"7.1","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"17.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"5.9","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"12.9","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"2.2","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"15.3","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"1.4","Cell RNA - TIME [nTPM]":"106.8","Cell RNA - U-138 MG [nTPM]":"206.9","Cell RNA - U-2 OS [nTPM]":"6.2","Cell RNA - U-2197 [nTPM]":"305.8","Cell RNA - U-251 MG [nTPM]":"37.6","Cell RNA - U-266\/70 [nTPM]":"1.2","Cell RNA - U-266\/84 [nTPM]":"1.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"138.9","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"13.9","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.4","Brain RNA - basal ganglia [nTPM]":"5.4","Brain RNA - cerebellum [nTPM]":"2.8","Brain RNA - cerebral cortex [nTPM]":"2.8","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"2.0","Brain RNA - medulla oblongata [nTPM]":"5.2","Brain RNA - midbrain [nTPM]":"6.0","Brain RNA - pons [nTPM]":"3.7","Brain RNA - spinal cord [nTPM]":"2.3","Brain RNA - thalamus [nTPM]":"4.7","Brain RNA - white matter [nTPM]":"5.0","Single Cell Type RNA - Adipocytes [nTPM]":"50.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.3","Single Cell Type RNA - Astrocytes [nTPM]":"34.9","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"25.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"6.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"5.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"132.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"8.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"105.2","Single Cell Type RNA - Endothelial cells [nTPM]":"36.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"82.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"40.8","Single Cell Type RNA - Fibroblasts [nTPM]":"388.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"22.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"34.6","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"123.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"39.0","Single Cell Type RNA - Late spermatids [nTPM]":"22.8","Single Cell Type RNA - Leydig cells [nTPM]":"236.1","Single Cell Type RNA - Macrophages [nTPM]":"5.7","Single Cell Type RNA - Melanocytes [nTPM]":"42.7","Single Cell Type RNA - Microglial cells [nTPM]":"30.0","Single Cell Type RNA - monocytes [nTPM]":"2.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"76.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"218.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"227.2","Single Cell Type RNA - Plasma cells [nTPM]":"1.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"139.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"55.8","Single Cell Type RNA - Spermatocytes [nTPM]":"3.3","Single Cell Type RNA - Spermatogonia [nTPM]":"3.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"65.8","Single Cell Type RNA - T-cells [nTPM]":"4.3","Single Cell Type RNA - Theca cells [nTPM]":"51.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"FERMT1","Gene synonym":["C20orf42","FLJ20116","KIND1","UNC112A","URP1"],"Ensembl":"ENSG00000101311","Gene description":"Fermitin family member 1","Uniprot":["Q9BQL6"],"Chromosome":"20","Position":"6074845-6123030","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"35.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"121.3","Oligodendrocyte precursor cells":"229.7","Pancreatic endocrine cells":"384.1","Undifferentiated cells":"95.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"59.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"84.3","HaCaT":"95.4","HBEC3-KT":"100.2","OE19":"75.1","RT4":"54.4"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"hippocampal formation":"2.0"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039778","HPA041966"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 16: Pancreatic endocrine cells - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039778":"AB_10805593","HPA041966":"AB_10795387"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.60e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.33e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.6","Tissue RNA - adrenal gland [nTPM]":"11.4","Tissue RNA - amygdala [nTPM]":"1.4","Tissue RNA - appendix [nTPM]":"9.3","Tissue RNA - basal ganglia [nTPM]":"2.2","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"1.5","Tissue RNA - cerebellum [nTPM]":"1.5","Tissue RNA - cerebral cortex [nTPM]":"1.4","Tissue RNA - cervix [nTPM]":"2.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"24.6","Tissue RNA - duodenum [nTPM]":"14.8","Tissue RNA - endometrium 1 [nTPM]":"2.3","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"12.8","Tissue RNA - fallopian tube [nTPM]":"3.5","Tissue RNA - gallbladder [nTPM]":"2.6","Tissue RNA - heart muscle [nTPM]":"1.0","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"2.0","Tissue RNA - kidney [nTPM]":"4.0","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"3.1","Tissue RNA - midbrain [nTPM]":"2.8","Tissue RNA - ovary [nTPM]":"4.2","Tissue RNA - pancreas [nTPM]":"2.7","Tissue RNA - parathyroid gland [nTPM]":"12.5","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"4.8","Tissue RNA - pons [nTPM]":"3.2","Tissue RNA - prostate [nTPM]":"5.0","Tissue RNA - rectum [nTPM]":"35.8","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"1.9","Tissue RNA - seminal vesicle [nTPM]":"4.3","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"17.6","Tissue RNA - small intestine [nTPM]":"11.0","Tissue RNA - smooth muscle [nTPM]":"2.0","Tissue RNA - spinal cord [nTPM]":"2.6","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"13.0","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"2.2","Tissue RNA - thymus [nTPM]":"2.4","Tissue RNA - thyroid gland [nTPM]":"2.9","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"5.1","Tissue RNA - urinary bladder [nTPM]":"6.8","Tissue RNA - vagina [nTPM]":"3.4","Tissue RNA - white matter [nTPM]":"3.4","Cell RNA - A-431 [nTPM]":"53.4","Cell RNA - A549 [nTPM]":"14.4","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.4","Cell RNA - ASC TERT1 [nTPM]":"5.0","Cell RNA - BEWO [nTPM]":"18.5","Cell RNA - BJ [nTPM]":"2.8","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.8","Cell RNA - CACO-2 [nTPM]":"24.8","Cell RNA - CAPAN-2 [nTPM]":"84.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"14.1","Cell RNA - fHDF\/TERT166 [nTPM]":"2.9","Cell RNA - GAMG [nTPM]":"6.3","Cell RNA - HaCaT [nTPM]":"95.4","Cell RNA - HAP1 [nTPM]":"36.8","Cell RNA - HBEC3-KT [nTPM]":"100.2","Cell RNA - HBF TERT88 [nTPM]":"2.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"2.6","Cell RNA - HEL [nTPM]":"8.2","Cell RNA - HeLa [nTPM]":"10.7","Cell RNA - Hep G2 [nTPM]":"26.8","Cell RNA - HHSteC [nTPM]":"1.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"2.5","Cell RNA - HSkMC [nTPM]":"4.8","Cell RNA - hTCEpi [nTPM]":"43.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.5","Cell RNA - hTERT-HME1 [nTPM]":"24.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.4","Cell RNA - HUVEC TERT2 [nTPM]":"1.2","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"2.4","Cell RNA - MCF7 [nTPM]":"1.4","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"2.4","Cell RNA - NTERA-2 [nTPM]":"11.5","Cell RNA - OE19 [nTPM]":"75.1","Cell RNA - PC-3 [nTPM]":"41.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"12.5","Cell RNA - RPMI-8226 [nTPM]":"29.9","Cell RNA - RPTEC TERT1 [nTPM]":"9.9","Cell RNA - RT4 [nTPM]":"54.4","Cell RNA - SCLC-21H [nTPM]":"7.7","Cell RNA - SH-SY5Y [nTPM]":"0.9","Cell RNA - SiHa [nTPM]":"8.8","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.7","Cell RNA - T-47d [nTPM]":"8.4","Cell RNA - THP-1 [nTPM]":"2.2","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"5.1","Cell RNA - U-2 OS [nTPM]":"3.4","Cell RNA - U-2197 [nTPM]":"0.7","Cell RNA - U-251 MG [nTPM]":"39.5","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"3.7","Cell RNA - U-937 [nTPM]":"9.5","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.4","Brain RNA - basal ganglia [nTPM]":"2.2","Brain RNA - cerebellum [nTPM]":"1.5","Brain RNA - cerebral cortex [nTPM]":"1.4","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"2.0","Brain RNA - medulla oblongata [nTPM]":"3.1","Brain RNA - midbrain [nTPM]":"2.8","Brain RNA - pons [nTPM]":"3.2","Brain RNA - spinal cord [nTPM]":"2.6","Brain RNA - thalamus [nTPM]":"2.2","Brain RNA - white matter [nTPM]":"3.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"41.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"51.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"44.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"121.3","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"16.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"65.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"61.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"34.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"31.8","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.6","Single Cell Type RNA - Erythroid cells [nTPM]":"8.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"40.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"31.3","Single Cell Type RNA - Fibroblasts [nTPM]":"7.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"46.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"13.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"49.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.1","Single Cell Type RNA - Leydig cells [nTPM]":"10.8","Single Cell Type RNA - Macrophages [nTPM]":"1.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"229.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"384.1","Single Cell Type RNA - Paneth cells [nTPM]":"23.5","Single Cell Type RNA - Peritubular cells [nTPM]":"3.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"80.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"43.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.3","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"6.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"95.2","Single Cell Type RNA - Urothelial cells [nTPM]":"44.8"},{"Gene":"FGF5","Gene synonym":[],"Ensembl":"ENSG00000138675","Gene description":"Fibroblast growth factor 5","Uniprot":["P12034"],"Chromosome":"4","Position":"80266599-80336680","Protein class":["Disease related genes","Human disease related genes","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Growth factor","Mitogen"],"Disease involvement":["Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"11.7","gallbladder":"3.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"1.9","Excitatory neurons":"9.4","Microglial cells":"1.9","Proximal tubular cells":"4.1"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"11.7"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"64.1","BJ hTERT+":"120.0","fHDF\/TERT166":"88.0","HBF TERT88":"88.0","LHCN-M2":"81.1","U-138 MG":"109.5","U-251 MG":"55.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010313","HPA042442"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Cytosol"],"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"CAB010313":"AB_2102677","HPA042442":"AB_2678001"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.49e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-16"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"11.7","Tissue RNA - cerebral cortex [nTPM]":"1.2","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.4","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"3.4","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.6","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.8","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"2.7","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"1.1","Tissue RNA - smooth muscle [nTPM]":"1.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.5","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.5","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"6.1","Cell RNA - ASC TERT1 [nTPM]":"21.8","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"64.1","Cell RNA - BJ hTERT+ [nTPM]":"120.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.2","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"88.0","Cell RNA - GAMG [nTPM]":"1.2","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"22.5","Cell RNA - HBF TERT88 [nTPM]":"88.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.1","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"1.7","Cell RNA - HL-60 [nTPM]":"0.6","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"6.3","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"48.6","Cell RNA - hTERT-HME1 [nTPM]":"23.0","Cell RNA - hTERT-RPE1 [nTPM]":"27.9","Cell RNA - HUVEC TERT2 [nTPM]":"5.7","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"81.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"2.1","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"20.9","Cell RNA - U-138 MG [nTPM]":"109.5","Cell RNA - U-2 OS [nTPM]":"4.6","Cell RNA - U-2197 [nTPM]":"5.4","Cell RNA - U-251 MG [nTPM]":"55.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"6.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"2.4","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"11.7","Brain RNA - cerebral cortex [nTPM]":"1.2","Brain RNA - hippocampal formation [nTPM]":"0.6","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"2.7","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.5","Brain RNA - white matter [nTPM]":"0.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"FLG","Gene synonym":[],"Ensembl":"ENSG00000143631","Gene description":"Filaggrin","Uniprot":["P20930"],"Chromosome":"1","Position":"152302165-152325239","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":["Cancer-related genes","Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"29","RNA tissue specific nTPM":{"skin 1":"458.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"13","RNA single cell type specific nTPM":{"Suprabasal keratinocytes":"44.0"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"melanoma":"11.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"10.1","NTERA-2":"3.1","TIME":"2.1","U-2 OS":"2.4","U-2197":"2.6","WM-115":"2.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002210","HPA027505","HPA030188","HPA030189"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytoplasmic bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3800000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 28: Keratinocytes - Keratinization","Subcellular main location":["Cytoplasmic bodies"],"Subcellular additional location":null,"Antibody RRID":{"CAB002210":"AB_563731","HPA027505":"AB_10600107","HPA030188":"AB_10601749","HPA030189":"AB_10601999"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.41e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"15.7","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"6.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.5","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"12.0","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"1.4","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"1.6","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"0.4","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"1.2","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"2.7","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"1.8","Tissue RNA - skin 1 [nTPM]":"458.2","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.8","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"4.9","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"1.3","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.5","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"10.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.8","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"3.1","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"0.7","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"1.3","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"2.1","Cell RNA - U-138 MG [nTPM]":"0.8","Cell RNA - U-2 OS [nTPM]":"2.4","Cell RNA - U-2197 [nTPM]":"2.6","Cell RNA - U-251 MG [nTPM]":"1.9","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"2.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"1.4","Brain RNA - medulla oblongata [nTPM]":"1.6","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"1.2","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"0.8","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.1","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"44.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"FZD6","Gene synonym":["Hfz6"],"Ensembl":"ENSG00000164930","Gene description":"Frizzled class receptor 6","Uniprot":["O60353"],"Chromosome":"8","Position":"103298433-103332866","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"73.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"NK-cell":"4.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"NK-cells":"4.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTCEpi":"127.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017991"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA017991":"AB_1849138"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.20e-6"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.54e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.7","Tissue RNA - adrenal gland [nTPM]":"10.6","Tissue RNA - amygdala [nTPM]":"3.0","Tissue RNA - appendix [nTPM]":"4.2","Tissue RNA - basal ganglia [nTPM]":"2.8","Tissue RNA - bone marrow [nTPM]":"1.0","Tissue RNA - breast [nTPM]":"15.1","Tissue RNA - cerebellum [nTPM]":"3.1","Tissue RNA - cerebral cortex [nTPM]":"4.3","Tissue RNA - cervix [nTPM]":"14.2","Tissue RNA - choroid plexus [nTPM]":"5.7","Tissue RNA - colon [nTPM]":"7.0","Tissue RNA - duodenum [nTPM]":"5.7","Tissue RNA - endometrium 1 [nTPM]":"13.0","Tissue RNA - epididymis [nTPM]":"9.5","Tissue RNA - esophagus [nTPM]":"18.7","Tissue RNA - fallopian tube [nTPM]":"23.5","Tissue RNA - gallbladder [nTPM]":"10.6","Tissue RNA - heart muscle [nTPM]":"9.1","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"3.0","Tissue RNA - kidney [nTPM]":"14.5","Tissue RNA - liver [nTPM]":"4.0","Tissue RNA - lung [nTPM]":"18.6","Tissue RNA - lymph node [nTPM]":"5.1","Tissue RNA - medulla oblongata [nTPM]":"3.8","Tissue RNA - midbrain [nTPM]":"3.1","Tissue RNA - ovary [nTPM]":"5.4","Tissue RNA - pancreas [nTPM]":"11.2","Tissue RNA - parathyroid gland [nTPM]":"25.3","Tissue RNA - pituitary gland [nTPM]":"9.8","Tissue RNA - placenta [nTPM]":"15.1","Tissue RNA - pons [nTPM]":"3.8","Tissue RNA - prostate [nTPM]":"12.6","Tissue RNA - rectum [nTPM]":"7.0","Tissue RNA - retina [nTPM]":"4.6","Tissue RNA - salivary gland [nTPM]":"11.7","Tissue RNA - seminal vesicle [nTPM]":"10.3","Tissue RNA - skeletal muscle [nTPM]":"2.0","Tissue RNA - skin 1 [nTPM]":"24.0","Tissue RNA - small intestine [nTPM]":"4.6","Tissue RNA - smooth muscle [nTPM]":"9.3","Tissue RNA - spinal cord [nTPM]":"3.0","Tissue RNA - spleen [nTPM]":"4.0","Tissue RNA - stomach 1 [nTPM]":"7.4","Tissue RNA - testis [nTPM]":"3.6","Tissue RNA - thalamus [nTPM]":"3.3","Tissue RNA - thymus [nTPM]":"10.0","Tissue RNA - thyroid gland [nTPM]":"22.3","Tissue RNA - tongue [nTPM]":"5.6","Tissue RNA - tonsil [nTPM]":"9.9","Tissue RNA - urinary bladder [nTPM]":"21.6","Tissue RNA - vagina [nTPM]":"10.2","Tissue RNA - white matter [nTPM]":"3.2","Cell RNA - A-431 [nTPM]":"59.8","Cell RNA - A549 [nTPM]":"11.0","Cell RNA - AF22 [nTPM]":"29.6","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"7.9","Cell RNA - ASC TERT1 [nTPM]":"20.6","Cell RNA - BEWO [nTPM]":"17.1","Cell RNA - BJ [nTPM]":"31.0","Cell RNA - BJ hTERT+ [nTPM]":"34.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"27.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"17.6","Cell RNA - CACO-2 [nTPM]":"6.2","Cell RNA - CAPAN-2 [nTPM]":"47.8","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"51.4","Cell RNA - fHDF\/TERT166 [nTPM]":"29.7","Cell RNA - GAMG [nTPM]":"9.1","Cell RNA - HaCaT [nTPM]":"90.3","Cell RNA - HAP1 [nTPM]":"16.8","Cell RNA - HBEC3-KT [nTPM]":"65.7","Cell RNA - HBF TERT88 [nTPM]":"51.0","Cell RNA - HDLM-2 [nTPM]":"13.5","Cell RNA - HEK 293 [nTPM]":"18.0","Cell RNA - HEL [nTPM]":"31.4","Cell RNA - HeLa [nTPM]":"12.2","Cell RNA - Hep G2 [nTPM]":"8.5","Cell RNA - HHSteC [nTPM]":"93.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"23.0","Cell RNA - hTCEpi [nTPM]":"127.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"29.4","Cell RNA - hTERT-HME1 [nTPM]":"91.5","Cell RNA - hTERT-RPE1 [nTPM]":"67.1","Cell RNA - HUVEC TERT2 [nTPM]":"58.2","Cell RNA - JURKAT [nTPM]":"7.0","Cell RNA - K-562 [nTPM]":"3.2","Cell RNA - Karpas-707 [nTPM]":"27.0","Cell RNA - LHCN-M2 [nTPM]":"31.5","Cell RNA - MCF7 [nTPM]":"25.5","Cell RNA - MOLT-4 [nTPM]":"29.8","Cell RNA - NB-4 [nTPM]":"2.7","Cell RNA - NTERA-2 [nTPM]":"6.7","Cell RNA - OE19 [nTPM]":"4.7","Cell RNA - PC-3 [nTPM]":"20.6","Cell RNA - REH [nTPM]":"2.3","Cell RNA - RH-30 [nTPM]":"12.3","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"59.1","Cell RNA - RT4 [nTPM]":"39.5","Cell RNA - SCLC-21H [nTPM]":"10.0","Cell RNA - SH-SY5Y [nTPM]":"7.9","Cell RNA - SiHa [nTPM]":"44.8","Cell RNA - SK-BR-3 [nTPM]":"22.8","Cell RNA - SK-MEL-30 [nTPM]":"59.9","Cell RNA - SuSa [nTPM]":"15.8","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"11.6","Cell RNA - TIME [nTPM]":"4.1","Cell RNA - U-138 MG [nTPM]":"6.1","Cell RNA - U-2 OS [nTPM]":"32.0","Cell RNA - U-2197 [nTPM]":"24.9","Cell RNA - U-251 MG [nTPM]":"32.7","Cell RNA - U-266\/70 [nTPM]":"6.4","Cell RNA - U-266\/84 [nTPM]":"3.7","Cell RNA - U-698 [nTPM]":"13.3","Cell RNA - U-87 MG [nTPM]":"18.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"40.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.9","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"4.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"3.0","Brain RNA - basal ganglia [nTPM]":"2.8","Brain RNA - cerebellum [nTPM]":"3.1","Brain RNA - cerebral cortex [nTPM]":"4.3","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"3.0","Brain RNA - medulla oblongata [nTPM]":"3.8","Brain RNA - midbrain [nTPM]":"3.1","Brain RNA - pons [nTPM]":"3.8","Brain RNA - spinal cord [nTPM]":"3.0","Brain RNA - thalamus [nTPM]":"3.3","Brain RNA - white matter [nTPM]":"3.2","Single Cell Type RNA - Adipocytes [nTPM]":"38.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.5","Single Cell Type RNA - Astrocytes [nTPM]":"10.1","Single Cell Type RNA - B-cells [nTPM]":"2.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"46.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"15.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"51.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"42.7","Single Cell Type RNA - Bipolar cells [nTPM]":"4.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"35.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"22.7","Single Cell Type RNA - dendritic cells [nTPM]":"2.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"11.7","Single Cell Type RNA - Early spermatids [nTPM]":"9.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"51.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.8","Single Cell Type RNA - Endothelial cells [nTPM]":"42.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.3","Single Cell Type RNA - Erythroid cells [nTPM]":"6.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.1","Single Cell Type RNA - Fibroblasts [nTPM]":"7.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"73.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"11.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.9","Single Cell Type RNA - Hepatocytes [nTPM]":"3.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.4","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.4","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"5.1","Single Cell Type RNA - Late spermatids [nTPM]":"2.9","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"1.3","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"11.8","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.5","Single Cell Type RNA - Paneth cells [nTPM]":"3.2","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"8.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"53.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.7","Single Cell Type RNA - Spermatocytes [nTPM]":"7.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"41.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"44.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.6","Single Cell Type RNA - T-cells [nTPM]":"3.0","Single Cell Type RNA - Theca cells [nTPM]":"1.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.6","Single Cell Type RNA - Urothelial cells [nTPM]":"23.2"},{"Gene":"GPNMB","Gene synonym":["HGFIN","NMB"],"Ensembl":"ENSG00000136235","Gene description":"Glycoprotein nmb","Uniprot":["Q14956"],"Chromosome":"7","Position":"23235967-23275108","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Amyloidosis","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"581.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"327.1","Fibroblasts":"285.8","Hofbauer cells":"814.1","Macrophages":"328.9","Melanocytes":"597.7","Suprabasal keratinocytes":"359.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"354.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"2.1","intermediate monocyte":"3.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"monocytes":"3.9"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"ASC diff":"5015.0"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"olfactory bulb":"9.7"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"33000000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-2"},"Tissue RNA - adipose tissue [nTPM]":"152.9","Tissue RNA - adrenal gland [nTPM]":"25.9","Tissue RNA - amygdala [nTPM]":"20.9","Tissue RNA - appendix [nTPM]":"41.7","Tissue RNA - basal ganglia [nTPM]":"20.9","Tissue RNA - bone marrow [nTPM]":"6.6","Tissue RNA - breast [nTPM]":"135.6","Tissue RNA - cerebellum [nTPM]":"19.0","Tissue RNA - cerebral cortex [nTPM]":"70.9","Tissue RNA - cervix [nTPM]":"303.9","Tissue RNA - choroid plexus [nTPM]":"77.6","Tissue RNA - colon [nTPM]":"78.8","Tissue RNA - duodenum [nTPM]":"22.5","Tissue RNA - endometrium 1 [nTPM]":"180.9","Tissue RNA - epididymis [nTPM]":"43.8","Tissue RNA - esophagus [nTPM]":"111.8","Tissue RNA - fallopian tube [nTPM]":"72.8","Tissue RNA - gallbladder [nTPM]":"270.7","Tissue RNA - heart muscle [nTPM]":"323.5","Tissue RNA - hippocampal formation [nTPM]":"21.2","Tissue RNA - hypothalamus [nTPM]":"23.1","Tissue RNA - kidney [nTPM]":"32.7","Tissue RNA - liver [nTPM]":"52.5","Tissue RNA - lung [nTPM]":"215.8","Tissue RNA - lymph node [nTPM]":"169.0","Tissue RNA - medulla oblongata [nTPM]":"32.2","Tissue RNA - midbrain [nTPM]":"21.5","Tissue RNA - ovary [nTPM]":"77.7","Tissue RNA - pancreas [nTPM]":"20.6","Tissue RNA - parathyroid gland [nTPM]":"15.3","Tissue RNA - pituitary gland [nTPM]":"12.8","Tissue RNA - placenta [nTPM]":"148.6","Tissue RNA - pons [nTPM]":"31.0","Tissue RNA - prostate [nTPM]":"30.4","Tissue RNA - rectum [nTPM]":"92.9","Tissue RNA - retina [nTPM]":"2.9","Tissue RNA - salivary gland [nTPM]":"66.1","Tissue RNA - seminal vesicle [nTPM]":"55.8","Tissue RNA - skeletal muscle [nTPM]":"15.4","Tissue RNA - skin 1 [nTPM]":"581.2","Tissue RNA - small intestine [nTPM]":"48.5","Tissue RNA - smooth muscle [nTPM]":"151.5","Tissue RNA - spinal cord [nTPM]":"27.3","Tissue RNA - spleen [nTPM]":"31.9","Tissue RNA - stomach 1 [nTPM]":"37.1","Tissue RNA - testis [nTPM]":"26.2","Tissue RNA - thalamus [nTPM]":"34.6","Tissue RNA - thymus [nTPM]":"89.5","Tissue RNA - thyroid gland [nTPM]":"51.5","Tissue RNA - tongue [nTPM]":"72.4","Tissue RNA - tonsil [nTPM]":"103.4","Tissue RNA - urinary bladder [nTPM]":"190.9","Tissue RNA - vagina [nTPM]":"151.0","Tissue RNA - white matter [nTPM]":"66.5","Cell RNA - A-431 [nTPM]":"19.2","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"5015.0","Cell RNA - ASC TERT1 [nTPM]":"908.0","Cell RNA - BEWO [nTPM]":"0.4","Cell RNA - BJ [nTPM]":"33.6","Cell RNA - BJ hTERT+ [nTPM]":"564.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"27.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"116.2","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.8","Cell RNA - Daudi [nTPM]":"0.7","Cell RNA - EFO-21 [nTPM]":"1.4","Cell RNA - fHDF\/TERT166 [nTPM]":"109.5","Cell RNA - GAMG [nTPM]":"49.1","Cell RNA - HaCaT [nTPM]":"118.3","Cell RNA - HAP1 [nTPM]":"0.7","Cell RNA - HBEC3-KT [nTPM]":"0.7","Cell RNA - HBF TERT88 [nTPM]":"14.2","Cell RNA - HDLM-2 [nTPM]":"1.3","Cell RNA - HEK 293 [nTPM]":"1.3","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.9","Cell RNA - Hep G2 [nTPM]":"2.5","Cell RNA - HHSteC [nTPM]":"61.5","Cell RNA - HL-60 [nTPM]":"1.5","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"630.3","Cell RNA - hTCEpi [nTPM]":"134.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"46.3","Cell RNA - hTERT-HME1 [nTPM]":"4.7","Cell RNA - hTERT-RPE1 [nTPM]":"734.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"1.4","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.6","Cell RNA - LHCN-M2 [nTPM]":"150.2","Cell RNA - MCF7 [nTPM]":"3.5","Cell RNA - MOLT-4 [nTPM]":"0.7","Cell RNA - NB-4 [nTPM]":"0.7","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"0.5","Cell RNA - PC-3 [nTPM]":"0.5","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"1.4","Cell RNA - RPMI-8226 [nTPM]":"7.6","Cell RNA - RPTEC TERT1 [nTPM]":"71.2","Cell RNA - RT4 [nTPM]":"443.4","Cell RNA - SCLC-21H [nTPM]":"2.4","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"175.6","Cell RNA - SK-MEL-30 [nTPM]":"841.5","Cell RNA - SuSa [nTPM]":"1.3","Cell RNA - T-47d [nTPM]":"2.3","Cell RNA - THP-1 [nTPM]":"2.8","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"163.0","Cell RNA - U-2 OS [nTPM]":"17.8","Cell RNA - U-2197 [nTPM]":"297.8","Cell RNA - U-251 MG [nTPM]":"5.5","Cell RNA - U-266\/70 [nTPM]":"5.1","Cell RNA - U-266\/84 [nTPM]":"8.6","Cell RNA - U-698 [nTPM]":"1.2","Cell RNA - U-87 MG [nTPM]":"56.3","Cell RNA - U-937 [nTPM]":"2.6","Cell RNA - WM-115 [nTPM]":"166.1","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"2.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"3.9","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"20.9","Brain RNA - basal ganglia [nTPM]":"20.9","Brain RNA - cerebellum [nTPM]":"19.0","Brain RNA - cerebral cortex [nTPM]":"70.9","Brain RNA - hippocampal formation [nTPM]":"21.2","Brain RNA - hypothalamus [nTPM]":"23.1","Brain RNA - medulla oblongata [nTPM]":"32.2","Brain RNA - midbrain [nTPM]":"21.5","Brain RNA - pons [nTPM]":"31.0","Brain RNA - spinal cord [nTPM]":"27.3","Brain RNA - thalamus [nTPM]":"34.6","Brain RNA - white matter [nTPM]":"66.5","Single Cell Type RNA - Adipocytes [nTPM]":"18.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"24.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"3.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"327.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"58.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"150.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"204.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"16.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"75.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.2","Single Cell Type RNA - dendritic cells [nTPM]":"2.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.6","Single Cell Type RNA - Early spermatids [nTPM]":"3.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"44.0","Single Cell Type RNA - Endothelial cells [nTPM]":"15.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.6","Single Cell Type RNA - Fibroblasts [nTPM]":"285.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.5","Single Cell Type RNA - granulocytes [nTPM]":"22.7","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.6","Single Cell Type RNA - Hepatocytes [nTPM]":"5.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"814.1","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"188.4","Single Cell Type RNA - Langerhans cells [nTPM]":"100.7","Single Cell Type RNA - Late spermatids [nTPM]":"5.5","Single Cell Type RNA - Leydig cells [nTPM]":"129.8","Single Cell Type RNA - Macrophages [nTPM]":"328.9","Single Cell Type RNA - Melanocytes [nTPM]":"597.7","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"3.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"55.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"108.0","Single Cell Type RNA - Plasma cells [nTPM]":"10.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"53.4","Single Cell Type RNA - Spermatocytes [nTPM]":"3.9","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"65.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"359.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"28.9","Single Cell Type RNA - T-cells [nTPM]":"5.7","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"11.9"},{"Gene":"GTF2E2","Gene synonym":["FE","TF2E2","TFIIE-B"],"Ensembl":"ENSG00000197265","Gene description":"General transcription factor IIE subunit 2","Uniprot":["P29084"],"Chromosome":"8","Position":"30578318-30658236","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004816","CAB009603","HPA025065"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 22: Non-specific - Unknown function","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB009603":"AB_2114537","HPA004816":"AB_2667252","HPA025065":"AB_10601658"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.38e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.20e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.30e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.82e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Tissue RNA - adipose tissue [nTPM]":"24.5","Tissue RNA - adrenal gland [nTPM]":"29.1","Tissue RNA - amygdala [nTPM]":"14.9","Tissue RNA - appendix [nTPM]":"17.8","Tissue RNA - basal ganglia [nTPM]":"16.1","Tissue RNA - bone marrow [nTPM]":"9.4","Tissue RNA - breast [nTPM]":"19.9","Tissue RNA - cerebellum [nTPM]":"19.9","Tissue RNA - cerebral cortex [nTPM]":"19.3","Tissue RNA - cervix [nTPM]":"25.1","Tissue RNA - choroid plexus [nTPM]":"16.9","Tissue RNA - colon [nTPM]":"20.9","Tissue RNA - duodenum [nTPM]":"19.5","Tissue RNA - endometrium 1 [nTPM]":"19.4","Tissue RNA - epididymis [nTPM]":"17.2","Tissue RNA - esophagus [nTPM]":"26.4","Tissue RNA - fallopian tube [nTPM]":"16.4","Tissue RNA - gallbladder [nTPM]":"13.2","Tissue RNA - heart muscle [nTPM]":"16.2","Tissue RNA - hippocampal formation [nTPM]":"15.9","Tissue RNA - hypothalamus [nTPM]":"17.3","Tissue RNA - kidney [nTPM]":"21.4","Tissue RNA - liver [nTPM]":"28.1","Tissue RNA - lung [nTPM]":"17.8","Tissue RNA - lymph node [nTPM]":"25.9","Tissue RNA - medulla oblongata [nTPM]":"14.8","Tissue RNA - midbrain [nTPM]":"15.1","Tissue RNA - ovary [nTPM]":"30.3","Tissue RNA - pancreas [nTPM]":"51.8","Tissue RNA - parathyroid gland [nTPM]":"15.4","Tissue RNA - pituitary gland [nTPM]":"20.1","Tissue RNA - placenta [nTPM]":"16.8","Tissue RNA - pons [nTPM]":"15.0","Tissue RNA - prostate [nTPM]":"18.7","Tissue RNA - rectum [nTPM]":"16.0","Tissue RNA - retina [nTPM]":"11.6","Tissue RNA - salivary gland [nTPM]":"15.9","Tissue RNA - seminal vesicle [nTPM]":"14.6","Tissue RNA - skeletal muscle [nTPM]":"13.4","Tissue RNA - skin 1 [nTPM]":"20.6","Tissue RNA - small intestine [nTPM]":"17.5","Tissue RNA - smooth muscle [nTPM]":"18.5","Tissue RNA - spinal cord [nTPM]":"14.7","Tissue RNA - spleen [nTPM]":"20.4","Tissue RNA - stomach 1 [nTPM]":"24.4","Tissue RNA - testis [nTPM]":"32.7","Tissue RNA - thalamus [nTPM]":"16.5","Tissue RNA - thymus [nTPM]":"22.4","Tissue RNA - thyroid gland [nTPM]":"17.4","Tissue RNA - tongue [nTPM]":"11.0","Tissue RNA - tonsil [nTPM]":"26.6","Tissue RNA - urinary bladder [nTPM]":"24.1","Tissue RNA - vagina [nTPM]":"24.1","Tissue RNA - white matter [nTPM]":"15.8","Cell RNA - A-431 [nTPM]":"53.7","Cell RNA - A549 [nTPM]":"43.7","Cell RNA - AF22 [nTPM]":"29.2","Cell RNA - AN3-CA [nTPM]":"31.2","Cell RNA - ASC diff [nTPM]":"77.4","Cell RNA - ASC TERT1 [nTPM]":"68.2","Cell RNA - BEWO [nTPM]":"22.0","Cell RNA - BJ [nTPM]":"57.7","Cell RNA - BJ hTERT+ [nTPM]":"52.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"46.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"58.6","Cell RNA - CACO-2 [nTPM]":"26.2","Cell RNA - CAPAN-2 [nTPM]":"38.2","Cell RNA - Daudi [nTPM]":"70.0","Cell RNA - EFO-21 [nTPM]":"48.0","Cell RNA - fHDF\/TERT166 [nTPM]":"51.9","Cell RNA - GAMG [nTPM]":"67.0","Cell RNA - HaCaT [nTPM]":"37.8","Cell RNA - HAP1 [nTPM]":"49.1","Cell RNA - HBEC3-KT [nTPM]":"53.8","Cell RNA - HBF TERT88 [nTPM]":"61.5","Cell RNA - HDLM-2 [nTPM]":"31.8","Cell RNA - HEK 293 [nTPM]":"28.2","Cell RNA - HEL [nTPM]":"34.9","Cell RNA - HeLa [nTPM]":"28.9","Cell RNA - Hep G2 [nTPM]":"63.0","Cell RNA - HHSteC [nTPM]":"75.4","Cell RNA - HL-60 [nTPM]":"17.1","Cell RNA - HMC-1 [nTPM]":"29.5","Cell RNA - HSkMC [nTPM]":"50.6","Cell RNA - hTCEpi [nTPM]":"70.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"49.7","Cell RNA - hTERT-HME1 [nTPM]":"50.7","Cell RNA - hTERT-RPE1 [nTPM]":"46.3","Cell RNA - HUVEC TERT2 [nTPM]":"65.3","Cell RNA - JURKAT [nTPM]":"51.2","Cell RNA - K-562 [nTPM]":"68.7","Cell RNA - Karpas-707 [nTPM]":"42.1","Cell RNA - LHCN-M2 [nTPM]":"74.5","Cell RNA - MCF7 [nTPM]":"37.3","Cell RNA - MOLT-4 [nTPM]":"83.7","Cell RNA - NB-4 [nTPM]":"42.9","Cell RNA - NTERA-2 [nTPM]":"33.1","Cell RNA - OE19 [nTPM]":"66.0","Cell RNA - PC-3 [nTPM]":"51.9","Cell RNA - REH [nTPM]":"43.2","Cell RNA - RH-30 [nTPM]":"31.6","Cell RNA - RPMI-8226 [nTPM]":"35.4","Cell RNA - RPTEC TERT1 [nTPM]":"50.9","Cell RNA - RT4 [nTPM]":"36.7","Cell RNA - SCLC-21H [nTPM]":"22.4","Cell RNA - SH-SY5Y [nTPM]":"29.1","Cell RNA - SiHa [nTPM]":"32.1","Cell RNA - SK-BR-3 [nTPM]":"21.5","Cell RNA - SK-MEL-30 [nTPM]":"46.5","Cell RNA - SuSa [nTPM]":"38.3","Cell RNA - T-47d [nTPM]":"20.8","Cell RNA - THP-1 [nTPM]":"20.9","Cell RNA - TIME [nTPM]":"49.9","Cell RNA - U-138 MG [nTPM]":"30.6","Cell RNA - U-2 OS [nTPM]":"31.4","Cell RNA - U-2197 [nTPM]":"25.9","Cell RNA - U-251 MG [nTPM]":"39.8","Cell RNA - U-266\/70 [nTPM]":"42.6","Cell RNA - U-266\/84 [nTPM]":"62.7","Cell RNA - U-698 [nTPM]":"77.0","Cell RNA - U-87 MG [nTPM]":"48.2","Cell RNA - U-937 [nTPM]":"28.8","Cell RNA - WM-115 [nTPM]":"41.3","Blood RNA - basophil [nTPM]":"4.3","Blood RNA - classical monocyte [nTPM]":"4.2","Blood RNA - eosinophil [nTPM]":"6.4","Blood RNA - gdT-cell [nTPM]":"3.6","Blood RNA - intermediate monocyte [nTPM]":"3.5","Blood RNA - MAIT T-cell [nTPM]":"4.1","Blood RNA - memory B-cell [nTPM]":"18.8","Blood RNA - memory CD4 T-cell [nTPM]":"5.7","Blood RNA - memory CD8 T-cell [nTPM]":"7.6","Blood RNA - myeloid DC [nTPM]":"7.3","Blood RNA - naive B-cell [nTPM]":"11.7","Blood RNA - naive CD4 T-cell [nTPM]":"5.6","Blood RNA - naive CD8 T-cell [nTPM]":"5.5","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"9.7","Blood RNA - non-classical monocyte [nTPM]":"3.7","Blood RNA - plasmacytoid DC [nTPM]":"8.2","Blood RNA - T-reg [nTPM]":"7.0","Blood RNA - total PBMC [nTPM]":"2.8","Brain RNA - amygdala [nTPM]":"14.9","Brain RNA - basal ganglia [nTPM]":"16.1","Brain RNA - cerebellum [nTPM]":"19.9","Brain RNA - cerebral cortex [nTPM]":"19.3","Brain RNA - hippocampal formation [nTPM]":"15.9","Brain RNA - hypothalamus [nTPM]":"17.3","Brain RNA - medulla oblongata [nTPM]":"14.8","Brain RNA - midbrain [nTPM]":"15.1","Brain RNA - pons [nTPM]":"15.0","Brain RNA - spinal cord [nTPM]":"14.7","Brain RNA - thalamus [nTPM]":"16.5","Brain RNA - white matter [nTPM]":"15.8","Single Cell Type RNA - Adipocytes [nTPM]":"20.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.4","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"48.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"47.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"48.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"44.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"48.3","Single Cell Type RNA - Bipolar cells [nTPM]":"9.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"28.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"43.0","Single Cell Type RNA - dendritic cells [nTPM]":"32.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"26.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"31.5","Single Cell Type RNA - Early spermatids [nTPM]":"96.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"42.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"33.8","Single Cell Type RNA - Endothelial cells [nTPM]":"22.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.2","Single Cell Type RNA - Erythroid cells [nTPM]":"14.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"30.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"33.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"51.4","Single Cell Type RNA - Fibroblasts [nTPM]":"30.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"31.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"29.0","Single Cell Type RNA - granulocytes [nTPM]":"11.4","Single Cell Type RNA - Granulosa cells [nTPM]":"17.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.4","Single Cell Type RNA - Hepatocytes [nTPM]":"27.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"34.1","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"30.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.2","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"21.6","Single Cell Type RNA - Langerhans cells [nTPM]":"39.3","Single Cell Type RNA - Late spermatids [nTPM]":"58.9","Single Cell Type RNA - Leydig cells [nTPM]":"39.4","Single Cell Type RNA - Macrophages [nTPM]":"28.4","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"58.8","Single Cell Type RNA - Muller glia cells [nTPM]":"9.0","Single Cell Type RNA - NK-cells [nTPM]":"46.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"43.3","Single Cell Type RNA - Paneth cells [nTPM]":"23.4","Single Cell Type RNA - Peritubular cells [nTPM]":"70.7","Single Cell Type RNA - Plasma cells [nTPM]":"35.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"72.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"46.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"48.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"40.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.9","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"28.0","Single Cell Type RNA - Spermatocytes [nTPM]":"74.3","Single Cell Type RNA - Spermatogonia [nTPM]":"87.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"38.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"46.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"62.1","Single Cell Type RNA - T-cells [nTPM]":"36.9","Single Cell Type RNA - Theca cells [nTPM]":"26.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.5","Single Cell Type RNA - Urothelial cells [nTPM]":"91.8"},{"Gene":"GTF2H5","Gene synonym":["bA120J8.2","C6orf175","FLJ30544","TFB5","TFIIH","TTD","TTD-A","TTDA"],"Ensembl":"ENSG00000272047","Gene description":"General transcription factor IIH subunit 5","Uniprot":["Q6ZYL4"],"Chromosome":"6","Position":"158168350-158199344","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Transcription","Transcription regulation"],"Molecular function":null,"Disease involvement":["Disease variant","Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"425.8","Proximal tubular cells":"504.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.59e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.11e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Tissue RNA - adipose tissue [nTPM]":"18.0","Tissue RNA - adrenal gland [nTPM]":"21.5","Tissue RNA - amygdala [nTPM]":"18.9","Tissue RNA - appendix [nTPM]":"8.3","Tissue RNA - basal ganglia [nTPM]":"20.7","Tissue RNA - bone marrow [nTPM]":"5.1","Tissue RNA - breast [nTPM]":"14.1","Tissue RNA - cerebellum [nTPM]":"19.0","Tissue RNA - cerebral cortex [nTPM]":"32.5","Tissue RNA - cervix [nTPM]":"9.1","Tissue RNA - choroid plexus [nTPM]":"17.9","Tissue RNA - colon [nTPM]":"9.6","Tissue RNA - duodenum [nTPM]":"7.4","Tissue RNA - endometrium 1 [nTPM]":"8.0","Tissue RNA - epididymis [nTPM]":"20.8","Tissue RNA - esophagus [nTPM]":"10.1","Tissue RNA - fallopian tube [nTPM]":"10.7","Tissue RNA - gallbladder [nTPM]":"7.8","Tissue RNA - heart muscle [nTPM]":"14.0","Tissue RNA - hippocampal formation [nTPM]":"19.7","Tissue RNA - hypothalamus [nTPM]":"20.1","Tissue RNA - kidney [nTPM]":"17.7","Tissue RNA - liver [nTPM]":"21.8","Tissue RNA - lung [nTPM]":"7.7","Tissue RNA - lymph node [nTPM]":"9.9","Tissue RNA - medulla oblongata [nTPM]":"19.3","Tissue RNA - midbrain [nTPM]":"18.7","Tissue RNA - ovary [nTPM]":"10.2","Tissue RNA - pancreas [nTPM]":"11.3","Tissue RNA - parathyroid gland [nTPM]":"13.5","Tissue RNA - pituitary gland [nTPM]":"3.2","Tissue RNA - placenta [nTPM]":"8.3","Tissue RNA - pons [nTPM]":"19.6","Tissue RNA - prostate [nTPM]":"12.7","Tissue RNA - rectum [nTPM]":"7.8","Tissue RNA - retina [nTPM]":"18.2","Tissue RNA - salivary gland [nTPM]":"9.0","Tissue RNA - seminal vesicle [nTPM]":"10.8","Tissue RNA - skeletal muscle [nTPM]":"27.7","Tissue RNA - skin 1 [nTPM]":"7.2","Tissue RNA - small intestine [nTPM]":"8.2","Tissue RNA - smooth muscle [nTPM]":"9.6","Tissue RNA - spinal cord [nTPM]":"19.7","Tissue RNA - spleen [nTPM]":"9.2","Tissue RNA - stomach 1 [nTPM]":"8.9","Tissue RNA - testis [nTPM]":"15.1","Tissue RNA - thalamus [nTPM]":"19.3","Tissue RNA - thymus [nTPM]":"15.4","Tissue RNA - thyroid gland [nTPM]":"8.4","Tissue RNA - tongue [nTPM]":"18.1","Tissue RNA - tonsil [nTPM]":"9.8","Tissue RNA - urinary bladder [nTPM]":"11.3","Tissue RNA - vagina [nTPM]":"3.1","Tissue RNA - white matter [nTPM]":"21.3","Cell RNA - A-431 [nTPM]":"18.5","Cell RNA - A549 [nTPM]":"14.6","Cell RNA - AF22 [nTPM]":"24.3","Cell RNA - AN3-CA [nTPM]":"27.5","Cell RNA - ASC diff [nTPM]":"32.2","Cell RNA - ASC TERT1 [nTPM]":"40.7","Cell RNA - BEWO [nTPM]":"20.8","Cell RNA - BJ [nTPM]":"30.2","Cell RNA - BJ hTERT+ [nTPM]":"26.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"30.4","Cell RNA - CACO-2 [nTPM]":"10.2","Cell RNA - CAPAN-2 [nTPM]":"17.4","Cell RNA - Daudi [nTPM]":"20.6","Cell RNA - EFO-21 [nTPM]":"48.5","Cell RNA - fHDF\/TERT166 [nTPM]":"29.6","Cell RNA - GAMG [nTPM]":"42.7","Cell RNA - HaCaT [nTPM]":"13.7","Cell RNA - HAP1 [nTPM]":"12.0","Cell RNA - HBEC3-KT [nTPM]":"29.4","Cell RNA - HBF TERT88 [nTPM]":"29.3","Cell RNA - HDLM-2 [nTPM]":"26.6","Cell RNA - HEK 293 [nTPM]":"33.3","Cell RNA - HEL [nTPM]":"28.1","Cell RNA - HeLa [nTPM]":"16.1","Cell RNA - Hep G2 [nTPM]":"44.2","Cell RNA - HHSteC [nTPM]":"29.4","Cell RNA - HL-60 [nTPM]":"16.1","Cell RNA - HMC-1 [nTPM]":"14.4","Cell RNA - HSkMC [nTPM]":"36.2","Cell RNA - hTCEpi [nTPM]":"30.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"23.8","Cell RNA - hTERT-HME1 [nTPM]":"29.0","Cell RNA - hTERT-RPE1 [nTPM]":"48.5","Cell RNA - HUVEC TERT2 [nTPM]":"19.9","Cell RNA - JURKAT [nTPM]":"29.3","Cell RNA - K-562 [nTPM]":"34.3","Cell RNA - Karpas-707 [nTPM]":"14.7","Cell RNA - LHCN-M2 [nTPM]":"46.7","Cell RNA - MCF7 [nTPM]":"11.1","Cell RNA - MOLT-4 [nTPM]":"24.7","Cell RNA - NB-4 [nTPM]":"39.1","Cell RNA - NTERA-2 [nTPM]":"25.2","Cell RNA - OE19 [nTPM]":"23.2","Cell RNA - PC-3 [nTPM]":"17.3","Cell RNA - REH [nTPM]":"15.6","Cell RNA - RH-30 [nTPM]":"15.1","Cell RNA - RPMI-8226 [nTPM]":"32.4","Cell RNA - RPTEC TERT1 [nTPM]":"50.3","Cell RNA - RT4 [nTPM]":"16.2","Cell RNA - SCLC-21H [nTPM]":"18.4","Cell RNA - SH-SY5Y [nTPM]":"14.7","Cell RNA - SiHa [nTPM]":"26.9","Cell RNA - SK-BR-3 [nTPM]":"26.1","Cell RNA - SK-MEL-30 [nTPM]":"27.0","Cell RNA - SuSa [nTPM]":"31.0","Cell RNA - T-47d [nTPM]":"21.6","Cell RNA - THP-1 [nTPM]":"38.1","Cell RNA - TIME [nTPM]":"31.8","Cell RNA - U-138 MG [nTPM]":"18.4","Cell RNA - U-2 OS [nTPM]":"22.5","Cell RNA - U-2197 [nTPM]":"25.5","Cell RNA - U-251 MG [nTPM]":"39.4","Cell RNA - U-266\/70 [nTPM]":"14.1","Cell RNA - U-266\/84 [nTPM]":"16.9","Cell RNA - U-698 [nTPM]":"30.0","Cell RNA - U-87 MG [nTPM]":"37.1","Cell RNA - U-937 [nTPM]":"15.3","Cell RNA - WM-115 [nTPM]":"38.0","Blood RNA - basophil [nTPM]":"11.6","Blood RNA - classical monocyte [nTPM]":"23.8","Blood RNA - eosinophil [nTPM]":"16.9","Blood RNA - gdT-cell [nTPM]":"25.4","Blood RNA - intermediate monocyte [nTPM]":"31.1","Blood RNA - MAIT T-cell [nTPM]":"22.4","Blood RNA - memory B-cell [nTPM]":"32.7","Blood RNA - memory CD4 T-cell [nTPM]":"27.9","Blood RNA - memory CD8 T-cell [nTPM]":"25.9","Blood RNA - myeloid DC [nTPM]":"30.6","Blood RNA - naive B-cell [nTPM]":"27.8","Blood RNA - naive CD4 T-cell [nTPM]":"33.0","Blood RNA - naive CD8 T-cell [nTPM]":"31.7","Blood RNA - neutrophil [nTPM]":"5.6","Blood RNA - NK-cell [nTPM]":"31.9","Blood RNA - non-classical monocyte [nTPM]":"33.4","Blood RNA - plasmacytoid DC [nTPM]":"41.9","Blood RNA - T-reg [nTPM]":"35.9","Blood RNA - total PBMC [nTPM]":"24.3","Brain RNA - amygdala [nTPM]":"18.9","Brain RNA - basal ganglia [nTPM]":"20.7","Brain RNA - cerebellum [nTPM]":"19.0","Brain RNA - cerebral cortex [nTPM]":"32.5","Brain RNA - hippocampal formation [nTPM]":"19.7","Brain RNA - hypothalamus [nTPM]":"20.1","Brain RNA - medulla oblongata [nTPM]":"19.3","Brain RNA - midbrain [nTPM]":"18.7","Brain RNA - pons [nTPM]":"19.6","Brain RNA - spinal cord [nTPM]":"19.7","Brain RNA - thalamus [nTPM]":"19.3","Brain RNA - white matter [nTPM]":"21.3","Single Cell Type RNA - Adipocytes [nTPM]":"79.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"58.4","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"49.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"45.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"113.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"232.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"46.1","Single Cell Type RNA - Bipolar cells [nTPM]":"45.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"91.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"122.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"86.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"88.6","Single Cell Type RNA - Club cells [nTPM]":"130.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"141.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"187.8","Single Cell Type RNA - dendritic cells [nTPM]":"62.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"418.7","Single Cell Type RNA - Ductal cells [nTPM]":"130.1","Single Cell Type RNA - Early spermatids [nTPM]":"425.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"207.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"76.0","Single Cell Type RNA - Endothelial cells [nTPM]":"61.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"46.6","Single Cell Type RNA - Erythroid cells [nTPM]":"33.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"122.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"167.4","Single Cell Type RNA - Fibroblasts [nTPM]":"93.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"54.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"120.6","Single Cell Type RNA - granulocytes [nTPM]":"65.2","Single Cell Type RNA - Granulosa cells [nTPM]":"126.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"92.4","Single Cell Type RNA - Hepatocytes [nTPM]":"180.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"162.0","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"75.1","Single Cell Type RNA - Ionocytes [nTPM]":"166.8","Single Cell Type RNA - Kupffer cells [nTPM]":"80.0","Single Cell Type RNA - Langerhans cells [nTPM]":"49.2","Single Cell Type RNA - Late spermatids [nTPM]":"103.3","Single Cell Type RNA - Leydig cells [nTPM]":"112.5","Single Cell Type RNA - Macrophages [nTPM]":"80.3","Single Cell Type RNA - Melanocytes [nTPM]":"80.0","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"120.6","Single Cell Type RNA - Muller glia cells [nTPM]":"120.5","Single Cell Type RNA - NK-cells [nTPM]":"117.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"25.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"92.1","Single Cell Type RNA - Paneth cells [nTPM]":"52.7","Single Cell Type RNA - Peritubular cells [nTPM]":"110.2","Single Cell Type RNA - Plasma cells [nTPM]":"24.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"94.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"71.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"504.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"205.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"50.2","Single Cell Type RNA - Sertoli cells [nTPM]":"72.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"71.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"87.7","Single Cell Type RNA - Spermatocytes [nTPM]":"227.3","Single Cell Type RNA - Spermatogonia [nTPM]":"130.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"98.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"63.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"132.8","Single Cell Type RNA - T-cells [nTPM]":"57.8","Single Cell Type RNA - Theca cells [nTPM]":"177.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"76.1","Single Cell Type RNA - Urothelial cells [nTPM]":"127.2"},{"Gene":"HLA-A","Gene synonym":[],"Ensembl":"ENSG00000206503","Gene description":"Major histocompatibility complex, class I, A","Uniprot":["P04439"],"Chromosome":"6","Position":"29941260-29945884","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Ductal cells":"3747.8","Proximal enterocytes":"5267.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"1363.9","fHDF\/TERT166":"360.3","HBEC3-KT":"366.7","RPMI-8226":"372.1","U-266\/70":"344.6"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB078470"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000000","Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB078470":"AB_10985125"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.59e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.47e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Tissue RNA - adipose tissue [nTPM]":"635.4","Tissue RNA - adrenal gland [nTPM]":"714.2","Tissue RNA - amygdala [nTPM]":"15.0","Tissue RNA - appendix [nTPM]":"34.8","Tissue RNA - basal ganglia [nTPM]":"15.5","Tissue RNA - bone marrow [nTPM]":"137.7","Tissue RNA - breast [nTPM]":"566.7","Tissue RNA - cerebellum [nTPM]":"14.7","Tissue RNA - cerebral cortex [nTPM]":"36.5","Tissue RNA - cervix [nTPM]":"504.9","Tissue RNA - choroid plexus [nTPM]":"18.0","Tissue RNA - colon [nTPM]":"737.5","Tissue RNA - duodenum [nTPM]":"278.3","Tissue RNA - endometrium 1 [nTPM]":"476.1","Tissue RNA - epididymis [nTPM]":"181.1","Tissue RNA - esophagus [nTPM]":"366.8","Tissue RNA - fallopian tube [nTPM]":"390.3","Tissue RNA - gallbladder [nTPM]":"239.9","Tissue RNA - heart muscle [nTPM]":"473.4","Tissue RNA - hippocampal formation [nTPM]":"14.6","Tissue RNA - hypothalamus [nTPM]":"17.0","Tissue RNA - kidney [nTPM]":"687.0","Tissue RNA - liver [nTPM]":"392.0","Tissue RNA - lung [nTPM]":"1007.3","Tissue RNA - lymph node [nTPM]":"132.0","Tissue RNA - medulla oblongata [nTPM]":"19.1","Tissue RNA - midbrain [nTPM]":"15.8","Tissue RNA - ovary [nTPM]":"338.8","Tissue RNA - pancreas [nTPM]":"200.0","Tissue RNA - parathyroid gland [nTPM]":"18.5","Tissue RNA - pituitary gland [nTPM]":"406.5","Tissue RNA - placenta [nTPM]":"52.1","Tissue RNA - pons [nTPM]":"16.5","Tissue RNA - prostate [nTPM]":"370.9","Tissue RNA - rectum [nTPM]":"94.6","Tissue RNA - retina [nTPM]":"9.9","Tissue RNA - salivary gland [nTPM]":"364.1","Tissue RNA - seminal vesicle [nTPM]":"1.2","Tissue RNA - skeletal muscle [nTPM]":"246.5","Tissue RNA - skin 1 [nTPM]":"673.3","Tissue RNA - small intestine [nTPM]":"959.1","Tissue RNA - smooth muscle [nTPM]":"14.5","Tissue RNA - spinal cord [nTPM]":"16.8","Tissue RNA - spleen [nTPM]":"1413.1","Tissue RNA - stomach 1 [nTPM]":"442.2","Tissue RNA - testis [nTPM]":"132.6","Tissue RNA - thalamus [nTPM]":"18.0","Tissue RNA - thymus [nTPM]":"138.9","Tissue RNA - thyroid gland [nTPM]":"531.9","Tissue RNA - tongue [nTPM]":"14.5","Tissue RNA - tonsil [nTPM]":"178.3","Tissue RNA - urinary bladder [nTPM]":"412.3","Tissue RNA - vagina [nTPM]":"466.8","Tissue RNA - white matter [nTPM]":"18.3","Cell RNA - A-431 [nTPM]":"1363.9","Cell RNA - A549 [nTPM]":"35.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"205.9","Cell RNA - ASC TERT1 [nTPM]":"193.7","Cell RNA - BEWO [nTPM]":"1.4","Cell RNA - BJ [nTPM]":"1.4","Cell RNA - BJ hTERT+ [nTPM]":"2.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.3","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"4.0","Cell RNA - EFO-21 [nTPM]":"0.6","Cell RNA - fHDF\/TERT166 [nTPM]":"360.3","Cell RNA - GAMG [nTPM]":"179.1","Cell RNA - HaCaT [nTPM]":"31.2","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"366.7","Cell RNA - HBF TERT88 [nTPM]":"0.5","Cell RNA - HDLM-2 [nTPM]":"3.1","Cell RNA - HEK 293 [nTPM]":"13.5","Cell RNA - HEL [nTPM]":"237.5","Cell RNA - HeLa [nTPM]":"9.5","Cell RNA - Hep G2 [nTPM]":"7.4","Cell RNA - HHSteC [nTPM]":"11.2","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"14.4","Cell RNA - HSkMC [nTPM]":"2.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.5","Cell RNA - hTERT-HME1 [nTPM]":"1.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"177.8","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"1.4","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"1.1","Cell RNA - NB-4 [nTPM]":"24.3","Cell RNA - NTERA-2 [nTPM]":"2.9","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"4.1","Cell RNA - REH [nTPM]":"27.5","Cell RNA - RH-30 [nTPM]":"2.5","Cell RNA - RPMI-8226 [nTPM]":"372.1","Cell RNA - RPTEC TERT1 [nTPM]":"246.7","Cell RNA - RT4 [nTPM]":"276.5","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"12.4","Cell RNA - SiHa [nTPM]":"29.3","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"11.8","Cell RNA - SuSa [nTPM]":"82.8","Cell RNA - T-47d [nTPM]":"1.6","Cell RNA - THP-1 [nTPM]":"30.4","Cell RNA - TIME [nTPM]":"5.8","Cell RNA - U-138 MG [nTPM]":"18.7","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"5.8","Cell RNA - U-251 MG [nTPM]":"4.0","Cell RNA - U-266\/70 [nTPM]":"344.6","Cell RNA - U-266\/84 [nTPM]":"92.6","Cell RNA - U-698 [nTPM]":"77.7","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"199.9","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"321.6","Blood RNA - classical monocyte [nTPM]":"119.0","Blood RNA - eosinophil [nTPM]":"182.7","Blood RNA - gdT-cell [nTPM]":"164.7","Blood RNA - intermediate monocyte [nTPM]":"95.5","Blood RNA - MAIT T-cell [nTPM]":"134.8","Blood RNA - memory B-cell [nTPM]":"96.9","Blood RNA - memory CD4 T-cell [nTPM]":"125.4","Blood RNA - memory CD8 T-cell [nTPM]":"146.3","Blood RNA - myeloid DC [nTPM]":"18.6","Blood RNA - naive B-cell [nTPM]":"64.3","Blood RNA - naive CD4 T-cell [nTPM]":"86.5","Blood RNA - naive CD8 T-cell [nTPM]":"119.2","Blood RNA - neutrophil [nTPM]":"248.7","Blood RNA - NK-cell [nTPM]":"133.1","Blood RNA - non-classical monocyte [nTPM]":"109.6","Blood RNA - plasmacytoid DC [nTPM]":"54.6","Blood RNA - T-reg [nTPM]":"222.2","Blood RNA - total PBMC [nTPM]":"191.9","Brain RNA - amygdala [nTPM]":"15.0","Brain RNA - basal ganglia [nTPM]":"15.5","Brain RNA - cerebellum [nTPM]":"14.7","Brain RNA - cerebral cortex [nTPM]":"36.5","Brain RNA - hippocampal formation [nTPM]":"14.6","Brain RNA - hypothalamus [nTPM]":"17.0","Brain RNA - medulla oblongata [nTPM]":"19.1","Brain RNA - midbrain [nTPM]":"15.8","Brain RNA - pons [nTPM]":"16.5","Brain RNA - spinal cord [nTPM]":"16.8","Brain RNA - thalamus [nTPM]":"18.0","Brain RNA - white matter [nTPM]":"18.3","Single Cell Type RNA - Adipocytes [nTPM]":"1622.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"371.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"478.6","Single Cell Type RNA - Astrocytes [nTPM]":"22.9","Single Cell Type RNA - B-cells [nTPM]":"1316.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"856.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"886.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1417.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"228.8","Single Cell Type RNA - Bipolar cells [nTPM]":"30.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"289.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"188.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"147.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"936.5","Single Cell Type RNA - Club cells [nTPM]":"952.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"503.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.3","Single Cell Type RNA - dendritic cells [nTPM]":"1879.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"2631.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"88.0","Single Cell Type RNA - Ductal cells [nTPM]":"3747.8","Single Cell Type RNA - Early spermatids [nTPM]":"52.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"239.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"374.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1717.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"955.2","Single Cell Type RNA - Erythroid cells [nTPM]":"499.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1310.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.5","Single Cell Type RNA - Fibroblasts [nTPM]":"743.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"853.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"556.2","Single Cell Type RNA - granulocytes [nTPM]":"603.0","Single Cell Type RNA - Granulosa cells [nTPM]":"253.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1266.2","Single Cell Type RNA - Hepatocytes [nTPM]":"276.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"1840.9","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"19.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1755.3","Single Cell Type RNA - Ionocytes [nTPM]":"1265.4","Single Cell Type RNA - Kupffer cells [nTPM]":"1575.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1124.0","Single Cell Type RNA - Late spermatids [nTPM]":"95.6","Single Cell Type RNA - Leydig cells [nTPM]":"704.6","Single Cell Type RNA - Macrophages [nTPM]":"1419.1","Single Cell Type RNA - Melanocytes [nTPM]":"635.0","Single Cell Type RNA - Microglial cells [nTPM]":"67.5","Single Cell Type RNA - monocytes [nTPM]":"3258.0","Single Cell Type RNA - Muller glia cells [nTPM]":"170.4","Single Cell Type RNA - NK-cells [nTPM]":"3201.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"49.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1802.9","Single Cell Type RNA - Paneth cells [nTPM]":"2452.4","Single Cell Type RNA - Peritubular cells [nTPM]":"484.1","Single Cell Type RNA - Plasma cells [nTPM]":"1110.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1026.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5267.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"294.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"609.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.4","Single Cell Type RNA - Sertoli cells [nTPM]":"558.8","Single Cell Type RNA - Skeletal myocytes [nTPM]":"397.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"579.2","Single Cell Type RNA - Spermatocytes [nTPM]":"197.4","Single Cell Type RNA - Spermatogonia [nTPM]":"23.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"216.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"947.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.7","Single Cell Type RNA - T-cells [nTPM]":"2234.9","Single Cell Type RNA - Theca cells [nTPM]":"1021.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1225.4","Single Cell Type RNA - Urothelial cells [nTPM]":"1262.8"},{"Gene":"HLA-B","Gene synonym":["AS"],"Ensembl":"ENSG00000234745","Gene description":"Major histocompatibility complex, class I, B","Uniprot":["P01889"],"Chromosome":"6","Position":"31353872-31357188","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"2493.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"5683.6","NK-cells":"7881.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"638.3","EFO-21":"547.1","U-266\/70":"1285.6","U-698":"377.2"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015418"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"190000000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB015418":"AB_831547"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.90e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.28e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.24e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Tissue RNA - adipose tissue [nTPM]":"944.9","Tissue RNA - adrenal gland [nTPM]":"581.6","Tissue RNA - amygdala [nTPM]":"5.5","Tissue RNA - appendix [nTPM]":"429.4","Tissue RNA - basal ganglia [nTPM]":"8.1","Tissue RNA - bone marrow [nTPM]":"53.5","Tissue RNA - breast [nTPM]":"850.0","Tissue RNA - cerebellum [nTPM]":"5.5","Tissue RNA - cerebral cortex [nTPM]":"14.4","Tissue RNA - cervix [nTPM]":"552.0","Tissue RNA - choroid plexus [nTPM]":"6.0","Tissue RNA - colon [nTPM]":"912.0","Tissue RNA - duodenum [nTPM]":"4.7","Tissue RNA - endometrium 1 [nTPM]":"567.1","Tissue RNA - epididymis [nTPM]":"222.1","Tissue RNA - esophagus [nTPM]":"434.4","Tissue RNA - fallopian tube [nTPM]":"488.6","Tissue RNA - gallbladder [nTPM]":"461.2","Tissue RNA - heart muscle [nTPM]":"563.1","Tissue RNA - hippocampal formation [nTPM]":"4.6","Tissue RNA - hypothalamus [nTPM]":"6.7","Tissue RNA - kidney [nTPM]":"731.7","Tissue RNA - liver [nTPM]":"488.9","Tissue RNA - lung [nTPM]":"1646.3","Tissue RNA - lymph node [nTPM]":"1061.9","Tissue RNA - medulla oblongata [nTPM]":"9.6","Tissue RNA - midbrain [nTPM]":"10.4","Tissue RNA - ovary [nTPM]":"296.9","Tissue RNA - pancreas [nTPM]":"268.7","Tissue RNA - parathyroid gland [nTPM]":"24.2","Tissue RNA - pituitary gland [nTPM]":"288.3","Tissue RNA - placenta [nTPM]":"106.6","Tissue RNA - pons [nTPM]":"7.5","Tissue RNA - prostate [nTPM]":"439.2","Tissue RNA - rectum [nTPM]":"238.5","Tissue RNA - retina [nTPM]":"8.1","Tissue RNA - salivary gland [nTPM]":"485.9","Tissue RNA - seminal vesicle [nTPM]":"3.8","Tissue RNA - skeletal muscle [nTPM]":"237.9","Tissue RNA - skin 1 [nTPM]":"936.4","Tissue RNA - small intestine [nTPM]":"1295.6","Tissue RNA - smooth muscle [nTPM]":"75.4","Tissue RNA - spinal cord [nTPM]":"7.7","Tissue RNA - spleen [nTPM]":"2493.7","Tissue RNA - stomach 1 [nTPM]":"540.1","Tissue RNA - testis [nTPM]":"132.6","Tissue RNA - thalamus [nTPM]":"6.7","Tissue RNA - thymus [nTPM]":"4.4","Tissue RNA - thyroid gland [nTPM]":"593.2","Tissue RNA - tongue [nTPM]":"3.8","Tissue RNA - tonsil [nTPM]":"414.9","Tissue RNA - urinary bladder [nTPM]":"476.2","Tissue RNA - vagina [nTPM]":"582.0","Tissue RNA - white matter [nTPM]":"7.9","Cell RNA - A-431 [nTPM]":"638.3","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"13.5","Cell RNA - ASC TERT1 [nTPM]":"98.9","Cell RNA - BEWO [nTPM]":"3.8","Cell RNA - BJ [nTPM]":"0.5","Cell RNA - BJ hTERT+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"1.9","Cell RNA - Daudi [nTPM]":"22.7","Cell RNA - EFO-21 [nTPM]":"547.1","Cell RNA - fHDF\/TERT166 [nTPM]":"111.0","Cell RNA - GAMG [nTPM]":"203.2","Cell RNA - HaCaT [nTPM]":"231.9","Cell RNA - HAP1 [nTPM]":"116.4","Cell RNA - HBEC3-KT [nTPM]":"112.4","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"2.3","Cell RNA - HEK 293 [nTPM]":"29.9","Cell RNA - HEL [nTPM]":"8.3","Cell RNA - HeLa [nTPM]":"0.8","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"79.8","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"2.4","Cell RNA - HSkMC [nTPM]":"200.2","Cell RNA - hTCEpi [nTPM]":"0.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"13.9","Cell RNA - hTERT-RPE1 [nTPM]":"183.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"39.8","Cell RNA - K-562 [nTPM]":"1.3","Cell RNA - Karpas-707 [nTPM]":"30.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"1.5","Cell RNA - NB-4 [nTPM]":"161.4","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"19.7","Cell RNA - RH-30 [nTPM]":"3.4","Cell RNA - RPMI-8226 [nTPM]":"4.7","Cell RNA - RPTEC TERT1 [nTPM]":"163.5","Cell RNA - RT4 [nTPM]":"0.6","Cell RNA - SCLC-21H [nTPM]":"0.9","Cell RNA - SH-SY5Y [nTPM]":"3.7","Cell RNA - SiHa [nTPM]":"5.5","Cell RNA - SK-BR-3 [nTPM]":"1.4","Cell RNA - SK-MEL-30 [nTPM]":"1.4","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"32.6","Cell RNA - THP-1 [nTPM]":"6.2","Cell RNA - TIME [nTPM]":"134.7","Cell RNA - U-138 MG [nTPM]":"21.4","Cell RNA - U-2 OS [nTPM]":"4.8","Cell RNA - U-2197 [nTPM]":"4.9","Cell RNA - U-251 MG [nTPM]":"2.3","Cell RNA - U-266\/70 [nTPM]":"1285.6","Cell RNA - U-266\/84 [nTPM]":"291.0","Cell RNA - U-698 [nTPM]":"377.2","Cell RNA - U-87 MG [nTPM]":"1.1","Cell RNA - U-937 [nTPM]":"6.5","Cell RNA - WM-115 [nTPM]":"0.6","Blood RNA - basophil [nTPM]":"141.1","Blood RNA - classical monocyte [nTPM]":"196.5","Blood RNA - eosinophil [nTPM]":"232.6","Blood RNA - gdT-cell [nTPM]":"233.0","Blood RNA - intermediate monocyte [nTPM]":"163.6","Blood RNA - MAIT T-cell [nTPM]":"215.7","Blood RNA - memory B-cell [nTPM]":"162.4","Blood RNA - memory CD4 T-cell [nTPM]":"194.8","Blood RNA - memory CD8 T-cell [nTPM]":"198.8","Blood RNA - myeloid DC [nTPM]":"150.8","Blood RNA - naive B-cell [nTPM]":"113.0","Blood RNA - naive CD4 T-cell [nTPM]":"150.9","Blood RNA - naive CD8 T-cell [nTPM]":"212.0","Blood RNA - neutrophil [nTPM]":"420.5","Blood RNA - NK-cell [nTPM]":"179.3","Blood RNA - non-classical monocyte [nTPM]":"123.6","Blood RNA - plasmacytoid DC [nTPM]":"127.3","Blood RNA - T-reg [nTPM]":"213.1","Blood RNA - total PBMC [nTPM]":"400.2","Brain RNA - amygdala [nTPM]":"5.5","Brain RNA - basal ganglia [nTPM]":"8.1","Brain RNA - cerebellum [nTPM]":"5.5","Brain RNA - cerebral cortex [nTPM]":"14.4","Brain RNA - hippocampal formation [nTPM]":"4.6","Brain RNA - hypothalamus [nTPM]":"6.7","Brain RNA - medulla oblongata [nTPM]":"9.6","Brain RNA - midbrain [nTPM]":"10.4","Brain RNA - pons [nTPM]":"7.5","Brain RNA - spinal cord [nTPM]":"7.7","Brain RNA - thalamus [nTPM]":"6.7","Brain RNA - white matter [nTPM]":"7.9","Single Cell Type RNA - Adipocytes [nTPM]":"2836.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"913.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1007.9","Single Cell Type RNA - Astrocytes [nTPM]":"14.0","Single Cell Type RNA - B-cells [nTPM]":"2936.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1165.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"761.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1139.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"396.1","Single Cell Type RNA - Bipolar cells [nTPM]":"27.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"533.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"550.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"168.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"1382.6","Single Cell Type RNA - Club cells [nTPM]":"948.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"388.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"31.4","Single Cell Type RNA - dendritic cells [nTPM]":"3876.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"3264.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"68.4","Single Cell Type RNA - Ductal cells [nTPM]":"4206.8","Single Cell Type RNA - Early spermatids [nTPM]":"63.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"311.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"349.2","Single Cell Type RNA - Endothelial cells [nTPM]":"2480.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"836.0","Single Cell Type RNA - Erythroid cells [nTPM]":"550.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1771.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"182.3","Single Cell Type RNA - Fibroblasts [nTPM]":"777.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1044.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"773.2","Single Cell Type RNA - granulocytes [nTPM]":"620.5","Single Cell Type RNA - Granulosa cells [nTPM]":"212.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2189.2","Single Cell Type RNA - Hepatocytes [nTPM]":"701.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"2602.0","Single Cell Type RNA - Horizontal cells [nTPM]":"60.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2121.8","Single Cell Type RNA - Ionocytes [nTPM]":"1129.1","Single Cell Type RNA - Kupffer cells [nTPM]":"4229.7","Single Cell Type RNA - Langerhans cells [nTPM]":"2158.6","Single Cell Type RNA - Late spermatids [nTPM]":"65.7","Single Cell Type RNA - Leydig cells [nTPM]":"644.9","Single Cell Type RNA - Macrophages [nTPM]":"2674.7","Single Cell Type RNA - Melanocytes [nTPM]":"891.2","Single Cell Type RNA - Microglial cells [nTPM]":"126.5","Single Cell Type RNA - monocytes [nTPM]":"5683.6","Single Cell Type RNA - Muller glia cells [nTPM]":"209.2","Single Cell Type RNA - NK-cells [nTPM]":"7881.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"25.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2085.3","Single Cell Type RNA - Paneth cells [nTPM]":"2327.5","Single Cell Type RNA - Peritubular cells [nTPM]":"306.9","Single Cell Type RNA - Plasma cells [nTPM]":"2983.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"993.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4541.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"183.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"829.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"27.3","Single Cell Type RNA - Sertoli cells [nTPM]":"1314.8","Single Cell Type RNA - Skeletal myocytes [nTPM]":"356.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"729.7","Single Cell Type RNA - Spermatocytes [nTPM]":"652.9","Single Cell Type RNA - Spermatogonia [nTPM]":"91.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"360.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1004.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"50.9","Single Cell Type RNA - T-cells [nTPM]":"3661.2","Single Cell Type RNA - Theca cells [nTPM]":"1219.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1527.4","Single Cell Type RNA - Urothelial cells [nTPM]":"1161.2"},{"Gene":"HLA-C","Gene synonym":["D6S204","HLA-JY3","PSORS1"],"Ensembl":"ENSG00000204525","Gene description":"Major histocompatibility complex, class I, C","Uniprot":["P10321"],"Chromosome":"6","Position":"31268749-31272130","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"1445.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"3899.1","Proximal enterocytes":"3582.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"760.0","EFO-21":"795.5","RPTEC TERT1":"462.7","U-266\/70":"481.6","U-266\/84":"401.0","U-698":"289.3"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"240000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.12e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.16e-2"},"Tissue RNA - adipose tissue [nTPM]":"538.6","Tissue RNA - adrenal gland [nTPM]":"417.5","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"274.6","Tissue RNA - basal ganglia [nTPM]":"2.4","Tissue RNA - bone marrow [nTPM]":"122.3","Tissue RNA - breast [nTPM]":"507.4","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"0.9","Tissue RNA - cervix [nTPM]":"464.4","Tissue RNA - choroid plexus [nTPM]":"1.5","Tissue RNA - colon [nTPM]":"594.3","Tissue RNA - duodenum [nTPM]":"1.6","Tissue RNA - endometrium 1 [nTPM]":"434.8","Tissue RNA - epididymis [nTPM]":"259.5","Tissue RNA - esophagus [nTPM]":"277.6","Tissue RNA - fallopian tube [nTPM]":"411.7","Tissue RNA - gallbladder [nTPM]":"103.9","Tissue RNA - heart muscle [nTPM]":"424.3","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"561.0","Tissue RNA - liver [nTPM]":"485.7","Tissue RNA - lung [nTPM]":"1078.3","Tissue RNA - lymph node [nTPM]":"334.0","Tissue RNA - medulla oblongata [nTPM]":"1.6","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"266.3","Tissue RNA - pancreas [nTPM]":"245.3","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"269.6","Tissue RNA - placenta [nTPM]":"34.5","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"344.2","Tissue RNA - rectum [nTPM]":"27.7","Tissue RNA - retina [nTPM]":"13.7","Tissue RNA - salivary gland [nTPM]":"389.5","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"190.6","Tissue RNA - skin 1 [nTPM]":"449.6","Tissue RNA - small intestine [nTPM]":"750.0","Tissue RNA - smooth muscle [nTPM]":"51.0","Tissue RNA - spinal cord [nTPM]":"1.3","Tissue RNA - spleen [nTPM]":"1445.7","Tissue RNA - stomach 1 [nTPM]":"419.4","Tissue RNA - testis [nTPM]":"62.3","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"2.4","Tissue RNA - thyroid gland [nTPM]":"382.9","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"0.7","Tissue RNA - urinary bladder [nTPM]":"372.7","Tissue RNA - vagina [nTPM]":"377.5","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"760.0","Cell RNA - A549 [nTPM]":"1.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"120.1","Cell RNA - ASC TERT1 [nTPM]":"94.1","Cell RNA - BEWO [nTPM]":"1.7","Cell RNA - BJ [nTPM]":"3.1","Cell RNA - BJ hTERT+ [nTPM]":"0.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.3","Cell RNA - CACO-2 [nTPM]":"0.9","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"795.5","Cell RNA - fHDF\/TERT166 [nTPM]":"190.8","Cell RNA - GAMG [nTPM]":"208.7","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"188.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1.4","Cell RNA - HEK 293 [nTPM]":"170.4","Cell RNA - HEL [nTPM]":"0.8","Cell RNA - HeLa [nTPM]":"8.1","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.8","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"80.5","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.5","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"272.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"92.5","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"7.8","Cell RNA - NB-4 [nTPM]":"4.8","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.8","Cell RNA - REH [nTPM]":"1.9","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"1.9","Cell RNA - RPTEC TERT1 [nTPM]":"462.7","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.9","Cell RNA - SH-SY5Y [nTPM]":"1.5","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"2.2","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"3.3","Cell RNA - TIME [nTPM]":"0.6","Cell RNA - U-138 MG [nTPM]":"196.4","Cell RNA - U-2 OS [nTPM]":"65.8","Cell RNA - U-2197 [nTPM]":"2.3","Cell RNA - U-251 MG [nTPM]":"2.5","Cell RNA - U-266\/70 [nTPM]":"481.6","Cell RNA - U-266\/84 [nTPM]":"401.0","Cell RNA - U-698 [nTPM]":"289.3","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"8.2","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"1.9","Blood RNA - classical monocyte [nTPM]":"2.8","Blood RNA - eosinophil [nTPM]":"2.3","Blood RNA - gdT-cell [nTPM]":"0.7","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"2.8","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.9","Blood RNA - total PBMC [nTPM]":"46.1","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"2.4","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"0.9","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"1.6","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"1.3","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"1903.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"227.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"328.1","Single Cell Type RNA - Astrocytes [nTPM]":"13.1","Single Cell Type RNA - B-cells [nTPM]":"1576.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"729.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"757.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1082.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"236.8","Single Cell Type RNA - Bipolar cells [nTPM]":"33.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"457.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"342.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"61.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"807.8","Single Cell Type RNA - Club cells [nTPM]":"662.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"483.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"39.5","Single Cell Type RNA - dendritic cells [nTPM]":"2429.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"1994.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"84.1","Single Cell Type RNA - Ductal cells [nTPM]":"1966.4","Single Cell Type RNA - Early spermatids [nTPM]":"25.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"233.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"343.8","Single Cell Type RNA - Endothelial cells [nTPM]":"1466.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"482.2","Single Cell Type RNA - Erythroid cells [nTPM]":"301.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1511.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1010.7","Single Cell Type RNA - Fibroblasts [nTPM]":"608.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"648.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"557.2","Single Cell Type RNA - granulocytes [nTPM]":"344.1","Single Cell Type RNA - Granulosa cells [nTPM]":"256.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1390.0","Single Cell Type RNA - Hepatocytes [nTPM]":"469.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"1579.0","Single Cell Type RNA - Horizontal cells [nTPM]":"99.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1375.7","Single Cell Type RNA - Ionocytes [nTPM]":"923.7","Single Cell Type RNA - Kupffer cells [nTPM]":"2050.7","Single Cell Type RNA - Langerhans cells [nTPM]":"1492.7","Single Cell Type RNA - Late spermatids [nTPM]":"32.1","Single Cell Type RNA - Leydig cells [nTPM]":"507.3","Single Cell Type RNA - Macrophages [nTPM]":"1595.9","Single Cell Type RNA - Melanocytes [nTPM]":"836.0","Single Cell Type RNA - Microglial cells [nTPM]":"76.8","Single Cell Type RNA - monocytes [nTPM]":"2570.1","Single Cell Type RNA - Muller glia cells [nTPM]":"207.3","Single Cell Type RNA - NK-cells [nTPM]":"3899.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1272.7","Single Cell Type RNA - Paneth cells [nTPM]":"2195.7","Single Cell Type RNA - Peritubular cells [nTPM]":"333.6","Single Cell Type RNA - Plasma cells [nTPM]":"2482.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1038.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3582.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"232.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"548.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.0","Single Cell Type RNA - Sertoli cells [nTPM]":"1203.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"336.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"558.8","Single Cell Type RNA - Spermatocytes [nTPM]":"142.0","Single Cell Type RNA - Spermatogonia [nTPM]":"43.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"192.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"651.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"121.6","Single Cell Type RNA - T-cells [nTPM]":"2212.1","Single Cell Type RNA - Theca cells [nTPM]":"786.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1003.1","Single Cell Type RNA - Urothelial cells [nTPM]":"1160.6"},{"Gene":"HLA-DPA1","Gene synonym":["HLA-DP1A"],"Ensembl":"ENSG00000231389","Gene description":"Major histocompatibility complex, class II, DP alpha 1","Uniprot":["P20036"],"Chromosome":"6","Position":"33064569-33080775","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"319.9","lymphoid tissue":"359.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"1387.3","Kupffer cells":"1794.6","Langerhans cells":"8122.8","Macrophages":"2736.9","monocytes":"2940.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"81.8","intermediate monocyte":"187.4","memory B-cell":"150.4","myeloid DC":"296.0","naive B-cell":"136.5","non-classical monocyte":"124.1","plasmacytoid DC":"82.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"B-cells":"150.4","dendritic cells":"296.0","monocytes":"187.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"37.2","HDLM-2":"115.9","REH":"30.3","U-698":"26.1"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017967"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"240000","Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA017967":"AB_1853929"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.93e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Tissue RNA - adipose tissue [nTPM]":"180.8","Tissue RNA - adrenal gland [nTPM]":"108.0","Tissue RNA - amygdala [nTPM]":"2.2","Tissue RNA - appendix [nTPM]":"33.4","Tissue RNA - basal ganglia [nTPM]":"2.0","Tissue RNA - bone marrow [nTPM]":"12.8","Tissue RNA - breast [nTPM]":"138.4","Tissue RNA - cerebellum [nTPM]":"2.7","Tissue RNA - cerebral cortex [nTPM]":"3.3","Tissue RNA - cervix [nTPM]":"76.7","Tissue RNA - choroid plexus [nTPM]":"2.5","Tissue RNA - colon [nTPM]":"72.1","Tissue RNA - duodenum [nTPM]":"20.2","Tissue RNA - endometrium 1 [nTPM]":"55.3","Tissue RNA - epididymis [nTPM]":"8.3","Tissue RNA - esophagus [nTPM]":"43.1","Tissue RNA - fallopian tube [nTPM]":"63.0","Tissue RNA - gallbladder [nTPM]":"13.0","Tissue RNA - heart muscle [nTPM]":"62.0","Tissue RNA - hippocampal formation [nTPM]":"2.0","Tissue RNA - hypothalamus [nTPM]":"3.4","Tissue RNA - kidney [nTPM]":"99.0","Tissue RNA - liver [nTPM]":"36.8","Tissue RNA - lung [nTPM]":"319.9","Tissue RNA - lymph node [nTPM]":"51.3","Tissue RNA - medulla oblongata [nTPM]":"4.9","Tissue RNA - midbrain [nTPM]":"2.8","Tissue RNA - ovary [nTPM]":"24.9","Tissue RNA - pancreas [nTPM]":"28.6","Tissue RNA - parathyroid gland [nTPM]":"5.9","Tissue RNA - pituitary gland [nTPM]":"58.0","Tissue RNA - placenta [nTPM]":"3.4","Tissue RNA - pons [nTPM]":"4.3","Tissue RNA - prostate [nTPM]":"64.0","Tissue RNA - rectum [nTPM]":"16.1","Tissue RNA - retina [nTPM]":"2.0","Tissue RNA - salivary gland [nTPM]":"59.5","Tissue RNA - seminal vesicle [nTPM]":"16.2","Tissue RNA - skeletal muscle [nTPM]":"29.5","Tissue RNA - skin 1 [nTPM]":"66.3","Tissue RNA - small intestine [nTPM]":"174.4","Tissue RNA - smooth muscle [nTPM]":"14.6","Tissue RNA - spinal cord [nTPM]":"4.3","Tissue RNA - spleen [nTPM]":"359.6","Tissue RNA - stomach 1 [nTPM]":"52.1","Tissue RNA - testis [nTPM]":"13.4","Tissue RNA - thalamus [nTPM]":"3.1","Tissue RNA - thymus [nTPM]":"30.2","Tissue RNA - thyroid gland [nTPM]":"76.6","Tissue RNA - tongue [nTPM]":"7.3","Tissue RNA - tonsil [nTPM]":"51.5","Tissue RNA - urinary bladder [nTPM]":"58.6","Tissue RNA - vagina [nTPM]":"60.0","Tissue RNA - white matter [nTPM]":"4.4","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.8","Cell RNA - ASC TERT1 [nTPM]":"1.3","Cell RNA - BEWO [nTPM]":"1.1","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"4.9","Cell RNA - Daudi [nTPM]":"37.2","Cell RNA - EFO-21 [nTPM]":"5.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.9","Cell RNA - GAMG [nTPM]":"7.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"115.9","Cell RNA - HEK 293 [nTPM]":"2.5","Cell RNA - HEL [nTPM]":"6.2","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"11.6","Cell RNA - HSkMC [nTPM]":"1.7","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.6","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"3.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"30.3","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"4.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"2.9","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"1.3","Cell RNA - TIME [nTPM]":"2.6","Cell RNA - U-138 MG [nTPM]":"7.8","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"5.6","Cell RNA - U-266\/84 [nTPM]":"0.9","Cell RNA - U-698 [nTPM]":"26.1","Cell RNA - U-87 MG [nTPM]":"12.2","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"4.4","Blood RNA - basophil [nTPM]":"2.2","Blood RNA - classical monocyte [nTPM]":"81.8","Blood RNA - eosinophil [nTPM]":"6.6","Blood RNA - gdT-cell [nTPM]":"21.6","Blood RNA - intermediate monocyte [nTPM]":"187.4","Blood RNA - MAIT T-cell [nTPM]":"5.7","Blood RNA - memory B-cell [nTPM]":"150.4","Blood RNA - memory CD4 T-cell [nTPM]":"9.6","Blood RNA - memory CD8 T-cell [nTPM]":"23.9","Blood RNA - myeloid DC [nTPM]":"296.0","Blood RNA - naive B-cell [nTPM]":"136.5","Blood RNA - naive CD4 T-cell [nTPM]":"3.4","Blood RNA - naive CD8 T-cell [nTPM]":"15.7","Blood RNA - neutrophil [nTPM]":"3.0","Blood RNA - NK-cell [nTPM]":"20.9","Blood RNA - non-classical monocyte [nTPM]":"124.1","Blood RNA - plasmacytoid DC [nTPM]":"82.6","Blood RNA - T-reg [nTPM]":"29.2","Blood RNA - total PBMC [nTPM]":"136.0","Brain RNA - amygdala [nTPM]":"2.2","Brain RNA - basal ganglia [nTPM]":"2.0","Brain RNA - cerebellum [nTPM]":"2.7","Brain RNA - cerebral cortex [nTPM]":"3.3","Brain RNA - hippocampal formation [nTPM]":"2.0","Brain RNA - hypothalamus [nTPM]":"3.4","Brain RNA - medulla oblongata [nTPM]":"4.9","Brain RNA - midbrain [nTPM]":"2.8","Brain RNA - pons [nTPM]":"4.3","Brain RNA - spinal cord [nTPM]":"4.3","Brain RNA - thalamus [nTPM]":"3.1","Brain RNA - white matter [nTPM]":"4.4","Single Cell Type RNA - Adipocytes [nTPM]":"621.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"83.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"404.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"1387.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"206.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"2.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"41.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"110.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"64.3","Single Cell Type RNA - Club cells [nTPM]":"107.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - dendritic cells [nTPM]":"574.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"36.4","Single Cell Type RNA - Early spermatids [nTPM]":"2.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.1","Single Cell Type RNA - Endothelial cells [nTPM]":"337.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.2","Single Cell Type RNA - Erythroid cells [nTPM]":"80.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.3","Single Cell Type RNA - Fibroblasts [nTPM]":"53.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"48.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.8","Single Cell Type RNA - granulocytes [nTPM]":"64.6","Single Cell Type RNA - Granulosa cells [nTPM]":"14.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"62.2","Single Cell Type RNA - Hepatocytes [nTPM]":"7.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"1153.8","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.2","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"1794.6","Single Cell Type RNA - Langerhans cells [nTPM]":"8122.8","Single Cell Type RNA - Late spermatids [nTPM]":"11.7","Single Cell Type RNA - Leydig cells [nTPM]":"18.0","Single Cell Type RNA - Macrophages [nTPM]":"2736.9","Single Cell Type RNA - Melanocytes [nTPM]":"302.4","Single Cell Type RNA - Microglial cells [nTPM]":"32.8","Single Cell Type RNA - monocytes [nTPM]":"2940.3","Single Cell Type RNA - Muller glia cells [nTPM]":"5.1","Single Cell Type RNA - NK-cells [nTPM]":"94.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.7","Single Cell Type RNA - Paneth cells [nTPM]":"5.4","Single Cell Type RNA - Peritubular cells [nTPM]":"27.4","Single Cell Type RNA - Plasma cells [nTPM]":"100.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"114.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"42.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"129.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.0","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"29.8","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"4.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"175.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.8","Single Cell Type RNA - T-cells [nTPM]":"157.8","Single Cell Type RNA - Theca cells [nTPM]":"11.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"28.6","Single Cell Type RNA - Urothelial cells [nTPM]":"34.4"},{"Gene":"HLA-DPB1","Gene synonym":["HLA-DP1B"],"Ensembl":"ENSG00000223865","Gene description":"Major histocompatibility complex, class II, DP beta 1","Uniprot":["P04440"],"Chromosome":"6","Position":"33075990-33089696","Protein class":["Human disease related genes","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"278.7","lymphoid tissue":"409.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"1569.6","Kupffer cells":"2374.2","Langerhans cells":"12627.8","Macrophages":"2453.8","monocytes":"3754.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"285.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"B-cells":"227.8","dendritic cells":"285.5","monocytes":"137.5"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"HDLM-2":"65.9","REH":"26.5"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011078","HPA058509"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"470000","Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Cell Junctions"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA011078":"AB_1079378","HPA058509":"AB_2683737"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.38e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Tissue RNA - adipose tissue [nTPM]":"151.6","Tissue RNA - adrenal gland [nTPM]":"101.3","Tissue RNA - amygdala [nTPM]":"1.0","Tissue RNA - appendix [nTPM]":"42.0","Tissue RNA - basal ganglia [nTPM]":"1.0","Tissue RNA - bone marrow [nTPM]":"5.8","Tissue RNA - breast [nTPM]":"112.8","Tissue RNA - cerebellum [nTPM]":"3.3","Tissue RNA - cerebral cortex [nTPM]":"1.3","Tissue RNA - cervix [nTPM]":"68.2","Tissue RNA - choroid plexus [nTPM]":"0.9","Tissue RNA - colon [nTPM]":"69.4","Tissue RNA - duodenum [nTPM]":"12.4","Tissue RNA - endometrium 1 [nTPM]":"50.2","Tissue RNA - epididymis [nTPM]":"2.9","Tissue RNA - esophagus [nTPM]":"43.9","Tissue RNA - fallopian tube [nTPM]":"55.7","Tissue RNA - gallbladder [nTPM]":"17.2","Tissue RNA - heart muscle [nTPM]":"51.1","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"1.8","Tissue RNA - kidney [nTPM]":"96.1","Tissue RNA - liver [nTPM]":"38.6","Tissue RNA - lung [nTPM]":"278.7","Tissue RNA - lymph node [nTPM]":"66.7","Tissue RNA - medulla oblongata [nTPM]":"1.8","Tissue RNA - midbrain [nTPM]":"1.3","Tissue RNA - ovary [nTPM]":"26.2","Tissue RNA - pancreas [nTPM]":"32.4","Tissue RNA - parathyroid gland [nTPM]":"1.0","Tissue RNA - pituitary gland [nTPM]":"51.5","Tissue RNA - placenta [nTPM]":"0.8","Tissue RNA - pons [nTPM]":"1.8","Tissue RNA - prostate [nTPM]":"70.3","Tissue RNA - rectum [nTPM]":"2.5","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"57.2","Tissue RNA - seminal vesicle [nTPM]":"6.4","Tissue RNA - skeletal muscle [nTPM]":"25.1","Tissue RNA - skin 1 [nTPM]":"72.3","Tissue RNA - small intestine [nTPM]":"176.5","Tissue RNA - smooth muscle [nTPM]":"4.7","Tissue RNA - spinal cord [nTPM]":"2.1","Tissue RNA - spleen [nTPM]":"409.4","Tissue RNA - stomach 1 [nTPM]":"54.1","Tissue RNA - testis [nTPM]":"12.8","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"10.9","Tissue RNA - thyroid gland [nTPM]":"69.5","Tissue RNA - tongue [nTPM]":"1.3","Tissue RNA - tonsil [nTPM]":"42.2","Tissue RNA - urinary bladder [nTPM]":"49.2","Tissue RNA - vagina [nTPM]":"56.5","Tissue RNA - white matter [nTPM]":"3.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"3.6","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"1.3","Cell RNA - EFO-21 [nTPM]":"6.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"65.9","Cell RNA - HEK 293 [nTPM]":"1.9","Cell RNA - HEL [nTPM]":"1.5","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"1.4","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.9","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"4.9","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"26.5","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.9","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"1.8","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"7.2","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"4.4","Cell RNA - U-87 MG [nTPM]":"1.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"59.6","Blood RNA - eosinophil [nTPM]":"4.0","Blood RNA - gdT-cell [nTPM]":"14.8","Blood RNA - intermediate monocyte [nTPM]":"137.5","Blood RNA - MAIT T-cell [nTPM]":"1.8","Blood RNA - memory B-cell [nTPM]":"226.6","Blood RNA - memory CD4 T-cell [nTPM]":"5.1","Blood RNA - memory CD8 T-cell [nTPM]":"22.2","Blood RNA - myeloid DC [nTPM]":"285.5","Blood RNA - naive B-cell [nTPM]":"227.8","Blood RNA - naive CD4 T-cell [nTPM]":"2.3","Blood RNA - naive CD8 T-cell [nTPM]":"11.9","Blood RNA - neutrophil [nTPM]":"1.6","Blood RNA - NK-cell [nTPM]":"8.2","Blood RNA - non-classical monocyte [nTPM]":"60.3","Blood RNA - plasmacytoid DC [nTPM]":"77.5","Blood RNA - T-reg [nTPM]":"22.7","Blood RNA - total PBMC [nTPM]":"107.8","Brain RNA - amygdala [nTPM]":"1.0","Brain RNA - basal ganglia [nTPM]":"1.0","Brain RNA - cerebellum [nTPM]":"3.3","Brain RNA - cerebral cortex [nTPM]":"1.3","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"1.8","Brain RNA - medulla oblongata [nTPM]":"1.8","Brain RNA - midbrain [nTPM]":"1.3","Brain RNA - pons [nTPM]":"1.8","Brain RNA - spinal cord [nTPM]":"2.1","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"3.0","Single Cell Type RNA - Adipocytes [nTPM]":"354.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"67.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"330.7","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"1569.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"300.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"26.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Bipolar cells [nTPM]":"26.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"54.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"123.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"67.2","Single Cell Type RNA - Club cells [nTPM]":"62.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.8","Single Cell Type RNA - dendritic cells [nTPM]":"692.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"58.3","Single Cell Type RNA - Early spermatids [nTPM]":"3.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.3","Single Cell Type RNA - Endothelial cells [nTPM]":"297.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"87.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.1","Single Cell Type RNA - Fibroblasts [nTPM]":"62.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"48.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.7","Single Cell Type RNA - granulocytes [nTPM]":"61.6","Single Cell Type RNA - Granulosa cells [nTPM]":"13.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"97.1","Single Cell Type RNA - Hepatocytes [nTPM]":"8.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"1099.4","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.0","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"2374.2","Single Cell Type RNA - Langerhans cells [nTPM]":"12627.8","Single Cell Type RNA - Late spermatids [nTPM]":"10.1","Single Cell Type RNA - Leydig cells [nTPM]":"27.4","Single Cell Type RNA - Macrophages [nTPM]":"2453.8","Single Cell Type RNA - Melanocytes [nTPM]":"323.7","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"3754.7","Single Cell Type RNA - Muller glia cells [nTPM]":"43.3","Single Cell Type RNA - NK-cells [nTPM]":"203.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.4","Single Cell Type RNA - Paneth cells [nTPM]":"10.0","Single Cell Type RNA - Peritubular cells [nTPM]":"21.1","Single Cell Type RNA - Plasma cells [nTPM]":"50.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"28.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"154.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"60.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"54.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.9","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"47.5","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"7.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"233.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.0","Single Cell Type RNA - T-cells [nTPM]":"200.7","Single Cell Type RNA - Theca cells [nTPM]":"3.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.0","Single Cell Type RNA - Urothelial cells [nTPM]":"51.7"},{"Gene":"HLA-DQA1","Gene synonym":["CELIAC1","HLA-DQA"],"Ensembl":"ENSG00000196735","Gene description":"Major histocompatibility complex, class II, DQ alpha 1","Uniprot":["P01909"],"Chromosome":"6","Position":"32628179-32647062","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"333.9","lymphoid tissue":"335.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Langerhans cells":"4114.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"666.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"B-cells":"287.6","dendritic cells":"666.6","monocytes":"257.6"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"HDLM-2":"1419.1"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012315"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"200000","Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA012315":"AB_1853930"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.81e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Tissue RNA - adipose tissue [nTPM]":"61.7","Tissue RNA - adrenal gland [nTPM]":"45.7","Tissue RNA - amygdala [nTPM]":"2.3","Tissue RNA - appendix [nTPM]":"111.0","Tissue RNA - basal ganglia [nTPM]":"2.2","Tissue RNA - bone marrow [nTPM]":"7.1","Tissue RNA - breast [nTPM]":"41.6","Tissue RNA - cerebellum [nTPM]":"2.4","Tissue RNA - cerebral cortex [nTPM]":"2.8","Tissue RNA - cervix [nTPM]":"49.9","Tissue RNA - choroid plexus [nTPM]":"5.2","Tissue RNA - colon [nTPM]":"76.8","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"27.7","Tissue RNA - epididymis [nTPM]":"32.2","Tissue RNA - esophagus [nTPM]":"32.1","Tissue RNA - fallopian tube [nTPM]":"29.1","Tissue RNA - gallbladder [nTPM]":"127.4","Tissue RNA - heart muscle [nTPM]":"20.8","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"39.6","Tissue RNA - liver [nTPM]":"95.1","Tissue RNA - lung [nTPM]":"333.9","Tissue RNA - lymph node [nTPM]":"335.8","Tissue RNA - medulla oblongata [nTPM]":"4.3","Tissue RNA - midbrain [nTPM]":"2.6","Tissue RNA - ovary [nTPM]":"18.6","Tissue RNA - pancreas [nTPM]":"15.0","Tissue RNA - parathyroid gland [nTPM]":"2.6","Tissue RNA - pituitary gland [nTPM]":"15.2","Tissue RNA - placenta [nTPM]":"13.7","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"15.1","Tissue RNA - rectum [nTPM]":"115.8","Tissue RNA - retina [nTPM]":"1.9","Tissue RNA - salivary gland [nTPM]":"34.8","Tissue RNA - seminal vesicle [nTPM]":"7.8","Tissue RNA - skeletal muscle [nTPM]":"7.5","Tissue RNA - skin 1 [nTPM]":"30.0","Tissue RNA - small intestine [nTPM]":"74.0","Tissue RNA - smooth muscle [nTPM]":"19.2","Tissue RNA - spinal cord [nTPM]":"5.4","Tissue RNA - spleen [nTPM]":"180.0","Tissue RNA - stomach 1 [nTPM]":"103.3","Tissue RNA - testis [nTPM]":"12.2","Tissue RNA - thalamus [nTPM]":"3.4","Tissue RNA - thymus [nTPM]":"234.3","Tissue RNA - thyroid gland [nTPM]":"26.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"322.3","Tissue RNA - urinary bladder [nTPM]":"175.9","Tissue RNA - vagina [nTPM]":"16.3","Tissue RNA - white matter [nTPM]":"11.1","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"213.6","Cell RNA - EFO-21 [nTPM]":"1.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1419.1","Cell RNA - HEK 293 [nTPM]":"0.9","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"4.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"1.4","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"2.4","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.6","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"63.2","Cell RNA - U-266\/84 [nTPM]":"1.5","Cell RNA - U-698 [nTPM]":"156.1","Cell RNA - U-87 MG [nTPM]":"24.4","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"1.9","Blood RNA - classical monocyte [nTPM]":"105.8","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"2.4","Blood RNA - intermediate monocyte [nTPM]":"257.6","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"287.6","Blood RNA - memory CD4 T-cell [nTPM]":"3.3","Blood RNA - memory CD8 T-cell [nTPM]":"16.5","Blood RNA - myeloid DC [nTPM]":"666.6","Blood RNA - naive B-cell [nTPM]":"274.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"4.3","Blood RNA - neutrophil [nTPM]":"3.0","Blood RNA - NK-cell [nTPM]":"8.2","Blood RNA - non-classical monocyte [nTPM]":"68.3","Blood RNA - plasmacytoid DC [nTPM]":"162.7","Blood RNA - T-reg [nTPM]":"21.6","Blood RNA - total PBMC [nTPM]":"129.0","Brain RNA - amygdala [nTPM]":"2.3","Brain RNA - basal ganglia [nTPM]":"2.2","Brain RNA - cerebellum [nTPM]":"2.4","Brain RNA - cerebral cortex [nTPM]":"2.8","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"4.3","Brain RNA - midbrain [nTPM]":"2.6","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"5.4","Brain RNA - thalamus [nTPM]":"3.4","Brain RNA - white matter [nTPM]":"11.1","Single Cell Type RNA - Adipocytes [nTPM]":"67.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"86.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"972.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"50.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"28.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"19.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - dendritic cells [nTPM]":"179.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"97.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"38.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.4","Single Cell Type RNA - Fibroblasts [nTPM]":"14.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.9","Single Cell Type RNA - granulocytes [nTPM]":"50.4","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"12.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"381.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"518.6","Single Cell Type RNA - Langerhans cells [nTPM]":"4114.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"874.3","Single Cell Type RNA - Melanocytes [nTPM]":"71.2","Single Cell Type RNA - Microglial cells [nTPM]":"12.2","Single Cell Type RNA - monocytes [nTPM]":"957.1","Single Cell Type RNA - Muller glia cells [nTPM]":"1.0","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"96.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"27.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.5","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"41.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.1","Single Cell Type RNA - T-cells [nTPM]":"56.0","Single Cell Type RNA - Theca cells [nTPM]":"1.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.7","Single Cell Type RNA - Urothelial cells [nTPM]":"7.6"},{"Gene":"HLA-DQA2","Gene synonym":["HLA-DXA"],"Ensembl":"ENSG00000237541","Gene description":"Major histocompatibility complex, class II, DQ alpha 2","Uniprot":["P01906"],"Chromosome":"6","Position":"32741391-32747198","Protein class":["Human disease related genes","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"20.8","lymphoid tissue":"27.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Langerhans cells":"1196.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.9","Tissue RNA - adrenal gland [nTPM]":"4.5","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"7.2","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"3.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"3.9","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"2.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"3.0","Tissue RNA - fallopian tube [nTPM]":"2.8","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"2.3","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"5.8","Tissue RNA - liver [nTPM]":"1.7","Tissue RNA - lung [nTPM]":"20.8","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"1.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"2.5","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"2.5","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"3.4","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"1.4","Tissue RNA - skin 1 [nTPM]":"8.4","Tissue RNA - small intestine [nTPM]":"11.6","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"27.1","Tissue RNA - stomach 1 [nTPM]":"2.9","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"3.7","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"3.0","Tissue RNA - vagina [nTPM]":"3.6","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"46.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"179.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"23.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"7.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"144.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"20.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"1.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"110.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"78.9","Single Cell Type RNA - Langerhans cells [nTPM]":"1196.5","Single Cell Type RNA - Late spermatids [nTPM]":"2.0","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"243.1","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"125.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"9.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"23.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"13.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"HLA-DQB1","Gene synonym":["CELIAC1","HLA-DQB","IDDM1"],"Ensembl":"ENSG00000179344","Gene description":"Major histocompatibility complex, class II, DQ beta 1","Uniprot":[],"Chromosome":"6","Position":"32659467-32668383","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"179.1","lymphoid tissue":"301.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"995.1","Langerhans cells":"4144.8","Macrophages":"1090.5","monocytes":"1038.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"153.5","intermediate monocyte":"142.9","memory B-cell":"159.2","myeloid DC":"386.3","naive B-cell":"169.1","plasmacytoid DC":"116.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"169.1","dendritic cells":"386.3","monocytes":"153.5"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"HDLM-2":"599.9"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013667"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Rods & Rings"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Rods & Rings"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA013667":"AB_1853932"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.91e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Tissue RNA - adipose tissue [nTPM]":"56.6","Tissue RNA - adrenal gland [nTPM]":"23.9","Tissue RNA - amygdala [nTPM]":"2.2","Tissue RNA - appendix [nTPM]":"77.8","Tissue RNA - basal ganglia [nTPM]":"2.2","Tissue RNA - bone marrow [nTPM]":"40.0","Tissue RNA - breast [nTPM]":"45.3","Tissue RNA - cerebellum [nTPM]":"2.7","Tissue RNA - cerebral cortex [nTPM]":"3.1","Tissue RNA - cervix [nTPM]":"19.9","Tissue RNA - choroid plexus [nTPM]":"3.0","Tissue RNA - colon [nTPM]":"45.8","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"18.9","Tissue RNA - epididymis [nTPM]":"126.9","Tissue RNA - esophagus [nTPM]":"21.3","Tissue RNA - fallopian tube [nTPM]":"22.2","Tissue RNA - gallbladder [nTPM]":"43.6","Tissue RNA - heart muscle [nTPM]":"21.6","Tissue RNA - hippocampal formation [nTPM]":"2.0","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"34.3","Tissue RNA - liver [nTPM]":"37.1","Tissue RNA - lung [nTPM]":"179.1","Tissue RNA - lymph node [nTPM]":"301.8","Tissue RNA - medulla oblongata [nTPM]":"4.7","Tissue RNA - midbrain [nTPM]":"3.8","Tissue RNA - ovary [nTPM]":"7.4","Tissue RNA - pancreas [nTPM]":"14.3","Tissue RNA - parathyroid gland [nTPM]":"10.6","Tissue RNA - pituitary gland [nTPM]":"21.3","Tissue RNA - placenta [nTPM]":"10.1","Tissue RNA - pons [nTPM]":"2.9","Tissue RNA - prostate [nTPM]":"17.1","Tissue RNA - rectum [nTPM]":"39.0","Tissue RNA - retina [nTPM]":"1.7","Tissue RNA - salivary gland [nTPM]":"24.2","Tissue RNA - seminal vesicle [nTPM]":"11.9","Tissue RNA - skeletal muscle [nTPM]":"9.6","Tissue RNA - skin 1 [nTPM]":"31.8","Tissue RNA - small intestine [nTPM]":"78.0","Tissue RNA - smooth muscle [nTPM]":"11.2","Tissue RNA - spinal cord [nTPM]":"4.6","Tissue RNA - spleen [nTPM]":"139.3","Tissue RNA - stomach 1 [nTPM]":"128.0","Tissue RNA - testis [nTPM]":"7.0","Tissue RNA - thalamus [nTPM]":"3.1","Tissue RNA - thymus [nTPM]":"108.2","Tissue RNA - thyroid gland [nTPM]":"26.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"122.3","Tissue RNA - urinary bladder [nTPM]":"89.9","Tissue RNA - vagina [nTPM]":"16.9","Tissue RNA - white matter [nTPM]":"5.5","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"93.9","Cell RNA - EFO-21 [nTPM]":"2.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"19.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"19.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"599.9","Cell RNA - HEK 293 [nTPM]":"13.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"7.8","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"3.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"2.9","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"1.8","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"7.2","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.9","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"1.3","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"1.6","Cell RNA - SK-BR-3 [nTPM]":"1.1","Cell RNA - SK-MEL-30 [nTPM]":"1.4","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"3.3","Cell RNA - THP-1 [nTPM]":"10.9","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"0.8","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"68.7","Cell RNA - U-266\/84 [nTPM]":"2.1","Cell RNA - U-698 [nTPM]":"66.0","Cell RNA - U-87 MG [nTPM]":"47.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"153.5","Blood RNA - eosinophil [nTPM]":"27.9","Blood RNA - gdT-cell [nTPM]":"12.8","Blood RNA - intermediate monocyte [nTPM]":"142.9","Blood RNA - MAIT T-cell [nTPM]":"6.6","Blood RNA - memory B-cell [nTPM]":"159.2","Blood RNA - memory CD4 T-cell [nTPM]":"6.9","Blood RNA - memory CD8 T-cell [nTPM]":"20.0","Blood RNA - myeloid DC [nTPM]":"386.3","Blood RNA - naive B-cell [nTPM]":"169.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"6.3","Blood RNA - neutrophil [nTPM]":"11.8","Blood RNA - NK-cell [nTPM]":"10.4","Blood RNA - non-classical monocyte [nTPM]":"41.1","Blood RNA - plasmacytoid DC [nTPM]":"116.5","Blood RNA - T-reg [nTPM]":"41.1","Blood RNA - total PBMC [nTPM]":"217.0","Brain RNA - amygdala [nTPM]":"2.2","Brain RNA - basal ganglia [nTPM]":"2.2","Brain RNA - cerebellum [nTPM]":"2.7","Brain RNA - cerebral cortex [nTPM]":"3.1","Brain RNA - hippocampal formation [nTPM]":"2.0","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"4.7","Brain RNA - midbrain [nTPM]":"3.8","Brain RNA - pons [nTPM]":"2.9","Brain RNA - spinal cord [nTPM]":"4.6","Brain RNA - thalamus [nTPM]":"3.1","Brain RNA - white matter [nTPM]":"5.5","Single Cell Type RNA - Adipocytes [nTPM]":"162.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"181.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"995.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"89.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"23.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.3","Single Cell Type RNA - Bipolar cells [nTPM]":"5.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"32.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"40.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - dendritic cells [nTPM]":"188.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"38.8","Single Cell Type RNA - Early spermatids [nTPM]":"16.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.0","Single Cell Type RNA - Endothelial cells [nTPM]":"135.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.8","Single Cell Type RNA - Erythroid cells [nTPM]":"37.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.0","Single Cell Type RNA - Fibroblasts [nTPM]":"18.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"41.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.2","Single Cell Type RNA - granulocytes [nTPM]":"38.5","Single Cell Type RNA - Granulosa cells [nTPM]":"7.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.0","Single Cell Type RNA - Hepatocytes [nTPM]":"2.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"422.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.7","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"487.3","Single Cell Type RNA - Langerhans cells [nTPM]":"4144.8","Single Cell Type RNA - Late spermatids [nTPM]":"7.5","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"1090.5","Single Cell Type RNA - Melanocytes [nTPM]":"97.8","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"1038.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.1","Single Cell Type RNA - NK-cells [nTPM]":"25.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"28.3","Single Cell Type RNA - Paneth cells [nTPM]":"27.4","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"86.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"417.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"53.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.6","Single Cell Type RNA - Spermatocytes [nTPM]":"2.7","Single Cell Type RNA - Spermatogonia [nTPM]":"2.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"66.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - T-cells [nTPM]":"84.5","Single Cell Type RNA - Theca cells [nTPM]":"0.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"36.1","Single Cell Type RNA - Urothelial cells [nTPM]":"49.1"},{"Gene":"HLA-DRB1","Gene synonym":["HLA-DR1B"],"Ensembl":"ENSG00000196126","Gene description":"Major histocompatibility complex, class II, DR beta 1","Uniprot":["P01911"],"Chromosome":"6","Position":"32578769-32589848","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"581.3","lymphoid tissue":"651.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"2149.9","Langerhans cells":"11630.1","Macrophages":"3622.3","monocytes":"3104.1","Proximal enterocytes":"1849.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"47.5"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"749.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"B-cells":"257.9","dendritic cells":"749.2","monocytes":"371.3"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"1181.9","HMC-1":"159.7","THP-1":"140.4","U-266\/70":"150.3","U-698":"202.5","U-87 MG":"308.9"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015400","CAB034021","HPA043151"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB015400":"AB_784538","CAB034021":"AB_1124844","HPA043151":"AB_2678342"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Tissue RNA - adipose tissue [nTPM]":"311.4","Tissue RNA - adrenal gland [nTPM]":"162.1","Tissue RNA - amygdala [nTPM]":"7.2","Tissue RNA - appendix [nTPM]":"220.8","Tissue RNA - basal ganglia [nTPM]":"7.8","Tissue RNA - bone marrow [nTPM]":"61.3","Tissue RNA - breast [nTPM]":"239.4","Tissue RNA - cerebellum [nTPM]":"6.4","Tissue RNA - cerebral cortex [nTPM]":"47.5","Tissue RNA - cervix [nTPM]":"121.4","Tissue RNA - choroid plexus [nTPM]":"11.1","Tissue RNA - colon [nTPM]":"113.5","Tissue RNA - duodenum [nTPM]":"2.4","Tissue RNA - endometrium 1 [nTPM]":"90.3","Tissue RNA - epididymis [nTPM]":"140.6","Tissue RNA - esophagus [nTPM]":"71.7","Tissue RNA - fallopian tube [nTPM]":"119.4","Tissue RNA - gallbladder [nTPM]":"66.9","Tissue RNA - heart muscle [nTPM]":"134.6","Tissue RNA - hippocampal formation [nTPM]":"6.2","Tissue RNA - hypothalamus [nTPM]":"11.4","Tissue RNA - kidney [nTPM]":"217.5","Tissue RNA - liver [nTPM]":"100.6","Tissue RNA - lung [nTPM]":"581.3","Tissue RNA - lymph node [nTPM]":"651.4","Tissue RNA - medulla oblongata [nTPM]":"6.8","Tissue RNA - midbrain [nTPM]":"7.1","Tissue RNA - ovary [nTPM]":"40.4","Tissue RNA - pancreas [nTPM]":"50.8","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"80.2","Tissue RNA - placenta [nTPM]":"13.6","Tissue RNA - pons [nTPM]":"6.9","Tissue RNA - prostate [nTPM]":"88.4","Tissue RNA - rectum [nTPM]":"135.3","Tissue RNA - retina [nTPM]":"5.2","Tissue RNA - salivary gland [nTPM]":"93.8","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"58.3","Tissue RNA - skin 1 [nTPM]":"122.5","Tissue RNA - small intestine [nTPM]":"353.2","Tissue RNA - smooth muscle [nTPM]":"11.1","Tissue RNA - spinal cord [nTPM]":"9.9","Tissue RNA - spleen [nTPM]":"516.2","Tissue RNA - stomach 1 [nTPM]":"232.3","Tissue RNA - testis [nTPM]":"25.5","Tissue RNA - thalamus [nTPM]":"9.2","Tissue RNA - thymus [nTPM]":"254.3","Tissue RNA - thyroid gland [nTPM]":"129.5","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"257.4","Tissue RNA - urinary bladder [nTPM]":"116.2","Tissue RNA - vagina [nTPM]":"91.5","Tissue RNA - white matter [nTPM]":"13.4","Cell RNA - A-431 [nTPM]":"0.6","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.4","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"2.4","Cell RNA - EFO-21 [nTPM]":"17.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"1.9","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"4.7","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1181.9","Cell RNA - HEK 293 [nTPM]":"12.9","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"159.7","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"12.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"28.5","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"2.3","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"4.4","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"6.5","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"26.7","Cell RNA - SuSa [nTPM]":"1.5","Cell RNA - T-47d [nTPM]":"4.8","Cell RNA - THP-1 [nTPM]":"140.4","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"2.1","Cell RNA - U-251 MG [nTPM]":"0.7","Cell RNA - U-266\/70 [nTPM]":"150.3","Cell RNA - U-266\/84 [nTPM]":"4.4","Cell RNA - U-698 [nTPM]":"202.5","Cell RNA - U-87 MG [nTPM]":"308.9","Cell RNA - U-937 [nTPM]":"5.8","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"2.5","Blood RNA - classical monocyte [nTPM]":"323.0","Blood RNA - eosinophil [nTPM]":"53.7","Blood RNA - gdT-cell [nTPM]":"12.2","Blood RNA - intermediate monocyte [nTPM]":"371.3","Blood RNA - MAIT T-cell [nTPM]":"2.2","Blood RNA - memory B-cell [nTPM]":"225.4","Blood RNA - memory CD4 T-cell [nTPM]":"9.0","Blood RNA - memory CD8 T-cell [nTPM]":"27.2","Blood RNA - myeloid DC [nTPM]":"749.2","Blood RNA - naive B-cell [nTPM]":"257.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"12.2","Blood RNA - neutrophil [nTPM]":"8.9","Blood RNA - NK-cell [nTPM]":"21.0","Blood RNA - non-classical monocyte [nTPM]":"223.8","Blood RNA - plasmacytoid DC [nTPM]":"147.6","Blood RNA - T-reg [nTPM]":"35.4","Blood RNA - total PBMC [nTPM]":"411.8","Brain RNA - amygdala [nTPM]":"7.2","Brain RNA - basal ganglia [nTPM]":"7.8","Brain RNA - cerebellum [nTPM]":"6.4","Brain RNA - cerebral cortex [nTPM]":"47.5","Brain RNA - hippocampal formation [nTPM]":"6.2","Brain RNA - hypothalamus [nTPM]":"11.4","Brain RNA - medulla oblongata [nTPM]":"6.8","Brain RNA - midbrain [nTPM]":"7.1","Brain RNA - pons [nTPM]":"6.9","Brain RNA - spinal cord [nTPM]":"9.9","Brain RNA - thalamus [nTPM]":"9.2","Brain RNA - white matter [nTPM]":"13.4","Single Cell Type RNA - Adipocytes [nTPM]":"1241.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"147.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"609.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2149.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"173.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"78.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"51.8","Single Cell Type RNA - Bipolar cells [nTPM]":"2.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"96.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"150.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"30.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"90.1","Single Cell Type RNA - Club cells [nTPM]":"277.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"141.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.7","Single Cell Type RNA - dendritic cells [nTPM]":"484.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"92.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"272.8","Single Cell Type RNA - Early spermatids [nTPM]":"4.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.0","Single Cell Type RNA - Endothelial cells [nTPM]":"721.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"36.0","Single Cell Type RNA - Erythroid cells [nTPM]":"120.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"73.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.0","Single Cell Type RNA - Fibroblasts [nTPM]":"77.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"131.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.6","Single Cell Type RNA - granulocytes [nTPM]":"124.0","Single Cell Type RNA - Granulosa cells [nTPM]":"47.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"179.9","Single Cell Type RNA - Hepatocytes [nTPM]":"5.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1417.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"92.7","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"1755.3","Single Cell Type RNA - Langerhans cells [nTPM]":"11630.1","Single Cell Type RNA - Late spermatids [nTPM]":"12.3","Single Cell Type RNA - Leydig cells [nTPM]":"14.9","Single Cell Type RNA - Macrophages [nTPM]":"3622.3","Single Cell Type RNA - Melanocytes [nTPM]":"217.1","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"3104.1","Single Cell Type RNA - Muller glia cells [nTPM]":"7.7","Single Cell Type RNA - NK-cells [nTPM]":"55.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"89.1","Single Cell Type RNA - Paneth cells [nTPM]":"308.9","Single Cell Type RNA - Peritubular cells [nTPM]":"26.7","Single Cell Type RNA - Plasma cells [nTPM]":"120.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1849.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"218.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"357.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.7","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"47.9","Single Cell Type RNA - Spermatocytes [nTPM]":"2.4","Single Cell Type RNA - Spermatogonia [nTPM]":"3.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"147.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.8","Single Cell Type RNA - T-cells [nTPM]":"245.6","Single Cell Type RNA - Theca cells [nTPM]":"52.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"152.2","Single Cell Type RNA - Urothelial cells [nTPM]":"125.5"},{"Gene":"HR","Gene synonym":["ALUNC","AU"],"Ensembl":"ENSG00000168453","Gene description":"HR lysine demethylase and nuclear receptor corepressor","Uniprot":["O43593"],"Chromosome":"8","Position":"22114419-22133384","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Oxidoreductase"],"Disease involvement":["Disease variant","Hypotrichosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"20.9","skin 1":"52.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"91.4","Cone photoreceptor cells":"33.3","Distal enterocytes":"27.5","Gastric mucus-secreting cells":"26.5","Paneth cells":"31.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"21.2","HaCaT":"81.7","OE19":"39.9","SiHa":"28.8","T-47d":"30.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054888"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA054888":"AB_2682630"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.00e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.4","Tissue RNA - adrenal gland [nTPM]":"1.0","Tissue RNA - amygdala [nTPM]":"4.3","Tissue RNA - appendix [nTPM]":"1.8","Tissue RNA - basal ganglia [nTPM]":"6.7","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"2.7","Tissue RNA - cerebellum [nTPM]":"7.8","Tissue RNA - cerebral cortex [nTPM]":"14.5","Tissue RNA - cervix [nTPM]":"3.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"9.0","Tissue RNA - duodenum [nTPM]":"4.8","Tissue RNA - endometrium 1 [nTPM]":"1.6","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"20.9","Tissue RNA - fallopian tube [nTPM]":"1.1","Tissue RNA - gallbladder [nTPM]":"1.3","Tissue RNA - heart muscle [nTPM]":"2.3","Tissue RNA - hippocampal formation [nTPM]":"3.1","Tissue RNA - hypothalamus [nTPM]":"4.8","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"11.3","Tissue RNA - midbrain [nTPM]":"9.0","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"2.7","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"12.0","Tissue RNA - prostate [nTPM]":"3.8","Tissue RNA - rectum [nTPM]":"3.2","Tissue RNA - retina [nTPM]":"1.8","Tissue RNA - salivary gland [nTPM]":"5.1","Tissue RNA - seminal vesicle [nTPM]":"4.2","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"52.7","Tissue RNA - small intestine [nTPM]":"4.7","Tissue RNA - smooth muscle [nTPM]":"1.5","Tissue RNA - spinal cord [nTPM]":"2.4","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"7.7","Tissue RNA - testis [nTPM]":"5.3","Tissue RNA - thalamus [nTPM]":"8.8","Tissue RNA - thymus [nTPM]":"0.6","Tissue RNA - thyroid gland [nTPM]":"4.3","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"3.0","Tissue RNA - vagina [nTPM]":"11.7","Tissue RNA - white matter [nTPM]":"11.5","Cell RNA - A-431 [nTPM]":"1.9","Cell RNA - A549 [nTPM]":"21.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.6","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"2.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"20.7","Cell RNA - fHDF\/TERT166 [nTPM]":"1.5","Cell RNA - GAMG [nTPM]":"1.0","Cell RNA - HaCaT [nTPM]":"81.7","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"2.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"17.8","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"4.7","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"4.1","Cell RNA - hTCEpi [nTPM]":"12.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"1.4","Cell RNA - hTERT-RPE1 [nTPM]":"1.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"2.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"12.7","Cell RNA - MOLT-4 [nTPM]":"1.5","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"39.9","Cell RNA - PC-3 [nTPM]":"16.3","Cell RNA - REH [nTPM]":"1.9","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"5.7","Cell RNA - SCLC-21H [nTPM]":"1.0","Cell RNA - SH-SY5Y [nTPM]":"4.7","Cell RNA - SiHa [nTPM]":"28.8","Cell RNA - SK-BR-3 [nTPM]":"6.4","Cell RNA - SK-MEL-30 [nTPM]":"6.5","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"30.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.4","Cell RNA - U-2 OS [nTPM]":"17.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"7.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.3","Brain RNA - basal ganglia [nTPM]":"6.7","Brain RNA - cerebellum [nTPM]":"7.8","Brain RNA - cerebral cortex [nTPM]":"14.5","Brain RNA - hippocampal formation [nTPM]":"3.1","Brain RNA - hypothalamus [nTPM]":"4.8","Brain RNA - medulla oblongata [nTPM]":"11.3","Brain RNA - midbrain [nTPM]":"9.0","Brain RNA - pons [nTPM]":"12.0","Brain RNA - spinal cord [nTPM]":"2.4","Brain RNA - thalamus [nTPM]":"8.8","Brain RNA - white matter [nTPM]":"11.5","Single Cell Type RNA - Adipocytes [nTPM]":"1.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"91.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"2.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"2.1","Single Cell Type RNA - Late spermatids [nTPM]":"1.9","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"3.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"31.2","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.5","Single Cell Type RNA - Urothelial cells [nTPM]":"6.8"},{"Gene":"IL10","Gene synonym":["CSIF","IL-10","IL10A","TGIF"],"Ensembl":"ENSG00000136634","Gene description":"Interleukin 10","Uniprot":["P22301"],"Chromosome":"1","Position":"206767602-206774541","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Cytokine"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"6.7","lymphoid tissue":"7.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Hofbauer cells":"28.3","Kupffer cells":"44.4","Langerhans cells":"35.5","Macrophages":"99.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"thalamus":"3.5"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"2.1","intermediate monocyte":"1.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"monocytes":"2.1"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"HMC-1":"14.6","U-266\/70":"6.8"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013120","HPA071391"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":5670,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB013120":null,"HPA071391":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.7","Tissue RNA - adrenal gland [nTPM]":"2.1","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"7.7","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"3.2","Tissue RNA - breast [nTPM]":"0.7","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"0.8","Tissue RNA - choroid plexus [nTPM]":"0.9","Tissue RNA - colon [nTPM]":"1.0","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"1.5","Tissue RNA - fallopian tube [nTPM]":"1.4","Tissue RNA - gallbladder [nTPM]":"3.5","Tissue RNA - heart muscle [nTPM]":"1.1","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.5","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"1.6","Tissue RNA - lung [nTPM]":"1.5","Tissue RNA - lymph node [nTPM]":"5.7","Tissue RNA - medulla oblongata [nTPM]":"0.7","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.4","Tissue RNA - placenta [nTPM]":"1.9","Tissue RNA - pons [nTPM]":"0.6","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"1.3","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.7","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"1.1","Tissue RNA - smooth muscle [nTPM]":"3.1","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"4.9","Tissue RNA - stomach 1 [nTPM]":"0.8","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"3.5","Tissue RNA - thymus [nTPM]":"2.9","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"2.0","Tissue RNA - urinary bladder [nTPM]":"2.9","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"1.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"14.6","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"6.8","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"1.8","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.5","Brain RNA - medulla oblongata [nTPM]":"0.7","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.6","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"3.5","Brain RNA - white matter [nTPM]":"1.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"5.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"1.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"6.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"1.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"44.4","Single Cell Type RNA - Langerhans cells [nTPM]":"35.5","Single Cell Type RNA - Late spermatids [nTPM]":"2.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"99.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"12.9","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"IL12RB2","Gene synonym":[],"Ensembl":"ENSG00000081985","Gene description":"Interleukin 12 receptor subunit beta 2","Uniprot":["Q99665"],"Chromosome":"1","Position":"67307364-67398724","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"4.5","placenta":"7.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"8.4","Excitatory neurons":"22.5","Inhibitory neurons":"16.6","T-cells":"12.8"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"cervical cancer":"1.8","head and neck cancer":"2.5","melanoma":"5.6","renal cancer":"1.7"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"hippocampal formation":"4.5"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"21.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"35","RNA blood lineage specific nTPM":{"NK-cells":"21.3","T-cells":"6.0"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"HMC-1":"4.6","SCLC-21H":"6.8","SK-MEL-30":"18.4","THP-1":"13.4"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"olfactory bulb":"1.4"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA024168"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 58: T-cells - T-cell receptor","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA024168":"AB_1851629"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.11e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.9","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"1.2","Tissue RNA - appendix [nTPM]":"1.2","Tissue RNA - basal ganglia [nTPM]":"1.6","Tissue RNA - bone marrow [nTPM]":"0.8","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"2.3","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"0.8","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"4.5","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.8","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"1.8","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.7","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"2.6","Tissue RNA - parathyroid gland [nTPM]":"0.8","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"7.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"1.3","Tissue RNA - seminal vesicle [nTPM]":"0.7","Tissue RNA - skeletal muscle [nTPM]":"3.5","Tissue RNA - skin 1 [nTPM]":"1.4","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"1.4","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"0.9","Tissue RNA - urinary bladder [nTPM]":"0.7","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.7","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"1.2","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"4.6","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"6.8","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"18.4","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"13.4","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"6.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"3.2","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"1.6","Blood RNA - memory CD8 T-cell [nTPM]":"1.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"21.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"3.9","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"1.2","Brain RNA - basal ganglia [nTPM]":"1.6","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"2.3","Brain RNA - hippocampal formation [nTPM]":"4.5","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.7","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.3","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"8.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"0.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"12.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"IL13","Gene synonym":["ALRH","BHR1","IL-13","MGC116786","MGC116788","MGC116789","P600"],"Ensembl":"ENSG00000169194","Gene description":"Interleukin 13","Uniprot":["P35225"],"Chromosome":"5","Position":"132656263-132661110","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Cytokine"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"19","RNA tissue specific nTPM":{"testis":"24.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"96.7","Late spermatids":"200.7","Spermatocytes":"44.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"187","RNA cell line specific nTPM":{"HDLM-2":"41.1"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042421"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":40000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 83: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA042421":"AB_10795504"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"1.2","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"24.3","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.6","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"41.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"96.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"17.7","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"3.4","Single Cell Type RNA - Late spermatids [nTPM]":"200.7","Single Cell Type RNA - Leydig cells [nTPM]":"2.8","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"44.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"14.7","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"IL16","Gene synonym":["FLJ16806","FLJ42735","HsT19289","IL-16","LCF","prIL-16"],"Ensembl":"ENSG00000172349","Gene description":"Interleukin 16","Uniprot":["Q14005"],"Chromosome":"15","Position":"81159575-81314058","Protein class":["Cancer-related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Chemotaxis","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Cytokine"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"135.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"135.3","dendritic cells":"78.1","Kupffer cells":"59.2","Langerhans cells":"94.4","NK-cells":"121.5","Plasma cells":"55.6","T-cells":"76.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebellum":"57.3"},"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"27.7","HEL":"29.4","HMC-1":"50.6","RPMI-8226":"51.0","U-266\/70":"60.3","U-698":"25.8","U-937":"35.1"},"RNA mouse brain regional specificity":"Group enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"11","RNA mouse brain regional specific nTPM":{"cerebellum":"54.5","hippocampal formation":"27.0"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"12","RNA pig brain regional specific nTPM":{"cerebellum":"48.8"},"Antibody":["CAB005247","HPA018467","HPA048861"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles","Plasma membrane","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":208000,"Blood concentration - Conc. blood MS [pg\/L]":"7300","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"CAB005247":"AB_2124730","HPA018467":"AB_1851642","HPA048861":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.61e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Tissue RNA - adipose tissue [nTPM]":"18.9","Tissue RNA - adrenal gland [nTPM]":"6.3","Tissue RNA - amygdala [nTPM]":"3.5","Tissue RNA - appendix [nTPM]":"63.3","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"62.1","Tissue RNA - breast [nTPM]":"15.5","Tissue RNA - cerebellum [nTPM]":"57.3","Tissue RNA - cerebral cortex [nTPM]":"4.1","Tissue RNA - cervix [nTPM]":"9.6","Tissue RNA - choroid plexus [nTPM]":"13.8","Tissue RNA - colon [nTPM]":"14.4","Tissue RNA - duodenum [nTPM]":"11.3","Tissue RNA - endometrium 1 [nTPM]":"9.9","Tissue RNA - epididymis [nTPM]":"7.7","Tissue RNA - esophagus [nTPM]":"7.4","Tissue RNA - fallopian tube [nTPM]":"17.8","Tissue RNA - gallbladder [nTPM]":"16.2","Tissue RNA - heart muscle [nTPM]":"5.9","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"5.7","Tissue RNA - kidney [nTPM]":"3.2","Tissue RNA - liver [nTPM]":"9.7","Tissue RNA - lung [nTPM]":"23.7","Tissue RNA - lymph node [nTPM]":"132.6","Tissue RNA - medulla oblongata [nTPM]":"5.9","Tissue RNA - midbrain [nTPM]":"5.7","Tissue RNA - ovary [nTPM]":"6.1","Tissue RNA - pancreas [nTPM]":"2.6","Tissue RNA - parathyroid gland [nTPM]":"2.3","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"9.0","Tissue RNA - pons [nTPM]":"10.5","Tissue RNA - prostate [nTPM]":"5.8","Tissue RNA - rectum [nTPM]":"16.8","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"11.2","Tissue RNA - seminal vesicle [nTPM]":"4.5","Tissue RNA - skeletal muscle [nTPM]":"3.3","Tissue RNA - skin 1 [nTPM]":"12.0","Tissue RNA - small intestine [nTPM]":"39.9","Tissue RNA - smooth muscle [nTPM]":"9.8","Tissue RNA - spinal cord [nTPM]":"5.8","Tissue RNA - spleen [nTPM]":"86.2","Tissue RNA - stomach 1 [nTPM]":"15.6","Tissue RNA - testis [nTPM]":"4.2","Tissue RNA - thalamus [nTPM]":"5.2","Tissue RNA - thymus [nTPM]":"130.4","Tissue RNA - thyroid gland [nTPM]":"6.9","Tissue RNA - tongue [nTPM]":"8.5","Tissue RNA - tonsil [nTPM]":"135.3","Tissue RNA - urinary bladder [nTPM]":"18.9","Tissue RNA - vagina [nTPM]":"10.4","Tissue RNA - white matter [nTPM]":"7.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"17.5","Cell RNA - ASC TERT1 [nTPM]":"7.2","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"27.7","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"29.4","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.9","Cell RNA - HL-60 [nTPM]":"21.0","Cell RNA - HMC-1 [nTPM]":"50.6","Cell RNA - HSkMC [nTPM]":"0.9","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.6","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.4","Cell RNA - JURKAT [nTPM]":"3.5","Cell RNA - K-562 [nTPM]":"3.2","Cell RNA - Karpas-707 [nTPM]":"10.7","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"1.7","Cell RNA - NB-4 [nTPM]":"22.2","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"51.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"9.9","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"4.6","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"1.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"60.3","Cell RNA - U-266\/84 [nTPM]":"5.5","Cell RNA - U-698 [nTPM]":"25.8","Cell RNA - U-87 MG [nTPM]":"1.8","Cell RNA - U-937 [nTPM]":"35.1","Cell RNA - WM-115 [nTPM]":"1.5","Blood RNA - basophil [nTPM]":"252.8","Blood RNA - classical monocyte [nTPM]":"116.2","Blood RNA - eosinophil [nTPM]":"321.3","Blood RNA - gdT-cell [nTPM]":"164.5","Blood RNA - intermediate monocyte [nTPM]":"142.7","Blood RNA - MAIT T-cell [nTPM]":"185.9","Blood RNA - memory B-cell [nTPM]":"166.0","Blood RNA - memory CD4 T-cell [nTPM]":"170.6","Blood RNA - memory CD8 T-cell [nTPM]":"180.6","Blood RNA - myeloid DC [nTPM]":"150.9","Blood RNA - naive B-cell [nTPM]":"157.2","Blood RNA - naive CD4 T-cell [nTPM]":"224.9","Blood RNA - naive CD8 T-cell [nTPM]":"185.6","Blood RNA - neutrophil [nTPM]":"282.5","Blood RNA - NK-cell [nTPM]":"213.2","Blood RNA - non-classical monocyte [nTPM]":"149.1","Blood RNA - plasmacytoid DC [nTPM]":"113.7","Blood RNA - T-reg [nTPM]":"197.0","Blood RNA - total PBMC [nTPM]":"338.0","Brain RNA - amygdala [nTPM]":"3.5","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"57.3","Brain RNA - cerebral cortex [nTPM]":"4.1","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"5.7","Brain RNA - medulla oblongata [nTPM]":"5.9","Brain RNA - midbrain [nTPM]":"5.7","Brain RNA - pons [nTPM]":"10.5","Brain RNA - spinal cord [nTPM]":"5.8","Brain RNA - thalamus [nTPM]":"5.2","Brain RNA - white matter [nTPM]":"7.6","Single Cell Type RNA - Adipocytes [nTPM]":"9.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"135.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"1.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"78.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.6","Single Cell Type RNA - Endothelial cells [nTPM]":"7.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"20.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"15.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"27.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.7","Single Cell Type RNA - Hepatocytes [nTPM]":"9.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"59.2","Single Cell Type RNA - Langerhans cells [nTPM]":"94.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"10.8","Single Cell Type RNA - Macrophages [nTPM]":"33.1","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"30.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"121.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"18.0","Single Cell Type RNA - Plasma cells [nTPM]":"55.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.2","Single Cell Type RNA - Spermatocytes [nTPM]":"2.1","Single Cell Type RNA - Spermatogonia [nTPM]":"7.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"76.3","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.7","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"IL1A","Gene synonym":["IL-1A","IL1","IL1-ALPHA","IL1F1"],"Ensembl":"ENSG00000115008","Gene description":"Interleukin 1 alpha","Uniprot":["P01583"],"Chromosome":"2","Position":"112773925-112784493","Protein class":["Cancer-related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins","Transporters"],"Biological process":["Inflammatory response"],"Molecular function":["Cytokine","Mitogen","Pyrogen"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"13.3","testis":"10.4","urinary bladder":"26.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"22.6","Club cells":"9.8","Endometrial ciliated cells":"11.5","Glandular and luminal cells":"29.4","Macrophages":"30.6","Squamous epithelial cells":"9.4"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"22.3","urothelial cancer":"17.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"HBEC3-KT":"447.6","hTCEpi":"216.2","hTERT-HME1":"283.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":10800,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.52e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.03e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.54e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.03e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"0.4","Tissue RNA - bone marrow [nTPM]":"1.0","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"4.8","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"2.5","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"13.3","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"2.3","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"0.5","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"2.3","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"0.9","Tissue RNA - midbrain [nTPM]":"0.8","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"1.5","Tissue RNA - pons [nTPM]":"1.0","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"1.2","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.8","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.7","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"10.4","Tissue RNA - thalamus [nTPM]":"0.5","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"8.7","Tissue RNA - urinary bladder [nTPM]":"26.0","Tissue RNA - vagina [nTPM]":"1.3","Tissue RNA - white matter [nTPM]":"1.2","Cell RNA - A-431 [nTPM]":"12.5","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"13.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"0.8","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"52.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"65.9","Cell RNA - HaCaT [nTPM]":"3.6","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"447.6","Cell RNA - HBF TERT88 [nTPM]":"1.7","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.7","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"1.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"216.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.8","Cell RNA - hTERT-HME1 [nTPM]":"283.4","Cell RNA - hTERT-RPE1 [nTPM]":"3.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"4.2","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.5","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"55.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"1.6","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"1.7","Cell RNA - U-138 MG [nTPM]":"1.3","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"5.2","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"2.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.4","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"0.5","Brain RNA - medulla oblongata [nTPM]":"0.9","Brain RNA - midbrain [nTPM]":"0.8","Brain RNA - pons [nTPM]":"1.0","Brain RNA - spinal cord [nTPM]":"0.7","Brain RNA - thalamus [nTPM]":"0.5","Brain RNA - white matter [nTPM]":"1.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"9.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.6","Single Cell Type RNA - Early spermatids [nTPM]":"8.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.8","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"29.4","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"4.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"30.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"2.4"},{"Gene":"IL1B","Gene synonym":["IL-1B","IL1-BETA","IL1F2"],"Ensembl":"ENSG00000125538","Gene description":"Interleukin 1 beta","Uniprot":["P01584"],"Chromosome":"2","Position":"112829751-112836816","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins","Transporters"],"Biological process":["Inflammatory response"],"Molecular function":["Cytokine","Mitogen","Pyrogen"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"201.7","urinary bladder":"126.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Langerhans cells":"1451.9","Macrophages":"1510.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"neutrophil":"94.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"94.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"649.3","HBEC3-KT":"293.3","HMC-1":"235.1","hTEC\/SVTERT24-B":"319.1","hTERT-RPE1":"277.0","U-87 MG":"571.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":2330,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.31e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.49e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Tissue RNA - adipose tissue [nTPM]":"43.9","Tissue RNA - adrenal gland [nTPM]":"7.6","Tissue RNA - amygdala [nTPM]":"2.5","Tissue RNA - appendix [nTPM]":"53.6","Tissue RNA - basal ganglia [nTPM]":"2.2","Tissue RNA - bone marrow [nTPM]":"201.7","Tissue RNA - breast [nTPM]":"2.0","Tissue RNA - cerebellum [nTPM]":"3.1","Tissue RNA - cerebral cortex [nTPM]":"4.6","Tissue RNA - cervix [nTPM]":"3.7","Tissue RNA - choroid plexus [nTPM]":"4.2","Tissue RNA - colon [nTPM]":"8.1","Tissue RNA - duodenum [nTPM]":"3.0","Tissue RNA - endometrium 1 [nTPM]":"7.4","Tissue RNA - epididymis [nTPM]":"2.0","Tissue RNA - esophagus [nTPM]":"3.4","Tissue RNA - fallopian tube [nTPM]":"4.1","Tissue RNA - gallbladder [nTPM]":"19.0","Tissue RNA - heart muscle [nTPM]":"3.3","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"3.4","Tissue RNA - kidney [nTPM]":"7.7","Tissue RNA - liver [nTPM]":"9.1","Tissue RNA - lung [nTPM]":"17.4","Tissue RNA - lymph node [nTPM]":"9.5","Tissue RNA - medulla oblongata [nTPM]":"4.8","Tissue RNA - midbrain [nTPM]":"4.6","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"4.4","Tissue RNA - parathyroid gland [nTPM]":"3.0","Tissue RNA - pituitary gland [nTPM]":"2.6","Tissue RNA - placenta [nTPM]":"7.8","Tissue RNA - pons [nTPM]":"3.8","Tissue RNA - prostate [nTPM]":"6.1","Tissue RNA - rectum [nTPM]":"6.5","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"3.8","Tissue RNA - seminal vesicle [nTPM]":"1.8","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"3.5","Tissue RNA - smooth muscle [nTPM]":"9.2","Tissue RNA - spinal cord [nTPM]":"4.4","Tissue RNA - spleen [nTPM]":"17.8","Tissue RNA - stomach 1 [nTPM]":"25.5","Tissue RNA - testis [nTPM]":"1.1","Tissue RNA - thalamus [nTPM]":"2.8","Tissue RNA - thymus [nTPM]":"9.4","Tissue RNA - thyroid gland [nTPM]":"2.6","Tissue RNA - tongue [nTPM]":"7.0","Tissue RNA - tonsil [nTPM]":"12.8","Tissue RNA - urinary bladder [nTPM]":"126.2","Tissue RNA - vagina [nTPM]":"1.0","Tissue RNA - white matter [nTPM]":"6.6","Cell RNA - A-431 [nTPM]":"6.3","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.4","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"2.1","Cell RNA - BJ hTERT+ [nTPM]":"649.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.5","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"18.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.5","Cell RNA - GAMG [nTPM]":"11.3","Cell RNA - HaCaT [nTPM]":"14.7","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"293.3","Cell RNA - HBF TERT88 [nTPM]":"39.2","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"29.5","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"2.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"235.1","Cell RNA - HSkMC [nTPM]":"1.1","Cell RNA - hTCEpi [nTPM]":"8.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"319.1","Cell RNA - hTERT-HME1 [nTPM]":"103.5","Cell RNA - hTERT-RPE1 [nTPM]":"277.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"0.6","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"2.9","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"1.2","Cell RNA - PC-3 [nTPM]":"26.2","Cell RNA - REH [nTPM]":"1.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"48.2","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"1.7","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"2.5","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"2.8","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"15.3","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.7","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"571.5","Cell RNA - U-937 [nTPM]":"14.0","Cell RNA - WM-115 [nTPM]":"22.7","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"12.3","Blood RNA - eosinophil [nTPM]":"4.4","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"19.5","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"19.5","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"94.1","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"7.7","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"3.4","Brain RNA - amygdala [nTPM]":"2.5","Brain RNA - basal ganglia [nTPM]":"2.2","Brain RNA - cerebellum [nTPM]":"3.1","Brain RNA - cerebral cortex [nTPM]":"4.6","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"3.4","Brain RNA - medulla oblongata [nTPM]":"4.8","Brain RNA - midbrain [nTPM]":"4.6","Brain RNA - pons [nTPM]":"3.8","Brain RNA - spinal cord [nTPM]":"4.4","Brain RNA - thalamus [nTPM]":"2.8","Brain RNA - white matter [nTPM]":"6.6","Single Cell Type RNA - Adipocytes [nTPM]":"23.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"28.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"14.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"25.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"16.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - dendritic cells [nTPM]":"7.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"33.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.0","Single Cell Type RNA - Endothelial cells [nTPM]":"20.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"58.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.6","Single Cell Type RNA - Fibroblasts [nTPM]":"8.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"44.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.4","Single Cell Type RNA - granulocytes [nTPM]":"41.7","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"108.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.7","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"130.5","Single Cell Type RNA - Langerhans cells [nTPM]":"1451.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1510.7","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"7.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.9","Single Cell Type RNA - Paneth cells [nTPM]":"10.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"9.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.4","Single Cell Type RNA - T-cells [nTPM]":"6.3","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.9","Single Cell Type RNA - Urothelial cells [nTPM]":"6.1"},{"Gene":"IL1R1","Gene synonym":["CD121A","D2S1473","IL1R","IL1RA"],"Ensembl":"ENSG00000115594","Gene description":"Interleukin 1 receptor type 1","Uniprot":["P14778"],"Chromosome":"2","Position":"102064544-102179874","Protein class":["Cancer-related genes","CD markers","Enzymes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Inflammatory response"],"Molecular function":["Hydrolase","Receptor"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"127.1","Endometrial stromal cells":"280.2","Glandular and luminal cells":"315.4","Hepatic stellate cells":"146.7","Langerhans cells":"188.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"624.9","ASC TERT1":"276.8","HHSteC":"196.3","HSkMC":"770.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001237","HPA005823","CAB007779","HPA029560"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1400000","Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"CAB007779":"AB_562073","HPA001237":null,"HPA005823":"AB_2667445","HPA029560":"AB_2673094"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.92e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-2"},"Tissue RNA - adipose tissue [nTPM]":"137.3","Tissue RNA - adrenal gland [nTPM]":"68.0","Tissue RNA - amygdala [nTPM]":"7.1","Tissue RNA - appendix [nTPM]":"69.5","Tissue RNA - basal ganglia [nTPM]":"8.3","Tissue RNA - bone marrow [nTPM]":"18.0","Tissue RNA - breast [nTPM]":"77.5","Tissue RNA - cerebellum [nTPM]":"7.5","Tissue RNA - cerebral cortex [nTPM]":"11.0","Tissue RNA - cervix [nTPM]":"161.1","Tissue RNA - choroid plexus [nTPM]":"16.2","Tissue RNA - colon [nTPM]":"39.3","Tissue RNA - duodenum [nTPM]":"20.7","Tissue RNA - endometrium 1 [nTPM]":"33.5","Tissue RNA - epididymis [nTPM]":"105.2","Tissue RNA - esophagus [nTPM]":"32.1","Tissue RNA - fallopian tube [nTPM]":"52.0","Tissue RNA - gallbladder [nTPM]":"92.0","Tissue RNA - heart muscle [nTPM]":"58.3","Tissue RNA - hippocampal formation [nTPM]":"7.6","Tissue RNA - hypothalamus [nTPM]":"9.0","Tissue RNA - kidney [nTPM]":"45.7","Tissue RNA - liver [nTPM]":"75.5","Tissue RNA - lung [nTPM]":"115.5","Tissue RNA - lymph node [nTPM]":"17.1","Tissue RNA - medulla oblongata [nTPM]":"16.2","Tissue RNA - midbrain [nTPM]":"8.4","Tissue RNA - ovary [nTPM]":"31.1","Tissue RNA - pancreas [nTPM]":"43.3","Tissue RNA - parathyroid gland [nTPM]":"126.7","Tissue RNA - pituitary gland [nTPM]":"13.1","Tissue RNA - placenta [nTPM]":"120.8","Tissue RNA - pons [nTPM]":"8.9","Tissue RNA - prostate [nTPM]":"66.7","Tissue RNA - rectum [nTPM]":"30.5","Tissue RNA - retina [nTPM]":"8.5","Tissue RNA - salivary gland [nTPM]":"34.2","Tissue RNA - seminal vesicle [nTPM]":"47.4","Tissue RNA - skeletal muscle [nTPM]":"18.6","Tissue RNA - skin 1 [nTPM]":"40.1","Tissue RNA - small intestine [nTPM]":"40.3","Tissue RNA - smooth muscle [nTPM]":"49.9","Tissue RNA - spinal cord [nTPM]":"10.0","Tissue RNA - spleen [nTPM]":"41.0","Tissue RNA - stomach 1 [nTPM]":"43.9","Tissue RNA - testis [nTPM]":"20.6","Tissue RNA - thalamus [nTPM]":"14.9","Tissue RNA - thymus [nTPM]":"21.7","Tissue RNA - thyroid gland [nTPM]":"52.5","Tissue RNA - tongue [nTPM]":"16.0","Tissue RNA - tonsil [nTPM]":"19.7","Tissue RNA - urinary bladder [nTPM]":"87.4","Tissue RNA - vagina [nTPM]":"40.2","Tissue RNA - white matter [nTPM]":"7.7","Cell RNA - A-431 [nTPM]":"2.0","Cell RNA - A549 [nTPM]":"12.8","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"10.8","Cell RNA - ASC diff [nTPM]":"624.9","Cell RNA - ASC TERT1 [nTPM]":"276.8","Cell RNA - BEWO [nTPM]":"4.4","Cell RNA - BJ [nTPM]":"27.4","Cell RNA - BJ hTERT+ [nTPM]":"123.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.7","Cell RNA - CACO-2 [nTPM]":"5.7","Cell RNA - CAPAN-2 [nTPM]":"3.4","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"19.8","Cell RNA - fHDF\/TERT166 [nTPM]":"55.0","Cell RNA - GAMG [nTPM]":"33.9","Cell RNA - HaCaT [nTPM]":"5.5","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"2.2","Cell RNA - HBF TERT88 [nTPM]":"16.1","Cell RNA - HDLM-2 [nTPM]":"55.5","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.7","Cell RNA - HeLa [nTPM]":"2.9","Cell RNA - Hep G2 [nTPM]":"31.3","Cell RNA - HHSteC [nTPM]":"196.3","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"770.6","Cell RNA - hTCEpi [nTPM]":"2.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.7","Cell RNA - hTERT-HME1 [nTPM]":"5.2","Cell RNA - hTERT-RPE1 [nTPM]":"8.4","Cell RNA - HUVEC TERT2 [nTPM]":"8.7","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"3.5","Cell RNA - Karpas-707 [nTPM]":"1.1","Cell RNA - LHCN-M2 [nTPM]":"28.1","Cell RNA - MCF7 [nTPM]":"5.6","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"1.2","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"5.6","Cell RNA - PC-3 [nTPM]":"0.9","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"2.0","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"18.3","Cell RNA - RT4 [nTPM]":"13.4","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"12.5","Cell RNA - SK-BR-3 [nTPM]":"7.7","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"3.6","Cell RNA - T-47d [nTPM]":"11.1","Cell RNA - THP-1 [nTPM]":"0.8","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"54.7","Cell RNA - U-2 OS [nTPM]":"3.6","Cell RNA - U-2197 [nTPM]":"92.1","Cell RNA - U-251 MG [nTPM]":"2.2","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"21.3","Cell RNA - U-937 [nTPM]":"0.6","Cell RNA - WM-115 [nTPM]":"3.6","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"1.2","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"7.1","Brain RNA - basal ganglia [nTPM]":"8.3","Brain RNA - cerebellum [nTPM]":"7.5","Brain RNA - cerebral cortex [nTPM]":"11.0","Brain RNA - hippocampal formation [nTPM]":"7.6","Brain RNA - hypothalamus [nTPM]":"9.0","Brain RNA - medulla oblongata [nTPM]":"16.2","Brain RNA - midbrain [nTPM]":"8.4","Brain RNA - pons [nTPM]":"8.9","Brain RNA - spinal cord [nTPM]":"10.0","Brain RNA - thalamus [nTPM]":"14.9","Brain RNA - white matter [nTPM]":"7.7","Single Cell Type RNA - Adipocytes [nTPM]":"99.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"73.2","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"1.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"31.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"46.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"28.6","Single Cell Type RNA - Club cells [nTPM]":"68.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.1","Single Cell Type RNA - dendritic cells [nTPM]":"2.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"31.7","Single Cell Type RNA - Early spermatids [nTPM]":"7.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"127.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"280.2","Single Cell Type RNA - Endothelial cells [nTPM]":"103.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"14.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"82.8","Single Cell Type RNA - Fibroblasts [nTPM]":"79.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"315.4","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"146.7","Single Cell Type RNA - Hepatocytes [nTPM]":"47.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.5","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"12.0","Single Cell Type RNA - Langerhans cells [nTPM]":"188.2","Single Cell Type RNA - Late spermatids [nTPM]":"12.6","Single Cell Type RNA - Leydig cells [nTPM]":"28.0","Single Cell Type RNA - Macrophages [nTPM]":"26.0","Single Cell Type RNA - Melanocytes [nTPM]":"19.6","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"7.0","Single Cell Type RNA - Muller glia cells [nTPM]":"9.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"1.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"65.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"37.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"34.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"38.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.9","Single Cell Type RNA - T-cells [nTPM]":"8.5","Single Cell Type RNA - Theca cells [nTPM]":"4.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.8","Single Cell Type RNA - Urothelial cells [nTPM]":"23.6"},{"Gene":"IL23R","Gene synonym":["IL-23R"],"Ensembl":"ENSG00000162594","Gene description":"Interleukin 23 receptor","Uniprot":["Q5VWK5"],"Chromosome":"1","Position":"67138907-67259979","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"1.6","testis":"1.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"11.1","Enteroendocrine cells":"3.0","Late spermatids":"6.0","T-cells":"4.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"8","RNA blood cell specific nTPM":{"MAIT T-cell":"21.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"29","RNA blood lineage specific nTPM":{"T-cells":"21.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HL-60":"2.4","HMC-1":"9.1","K-562":"3.6","U-2197":"13.8"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA056427"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA056427":"AB_2683129"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.64e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"1.6","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.9","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"0.4","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.6","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.5","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"2.4","Cell RNA - HMC-1 [nTPM]":"9.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"3.6","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.4","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"1.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"13.8","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.9","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"21.7","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.5","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"11.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.2","Single Cell Type RNA - Late spermatids [nTPM]":"6.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"4.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"IL31RA","Gene synonym":["CRL","CRL3","GLM-R","Glmr","IL-31RA"],"Ensembl":"ENSG00000164509","Gene description":"Interleukin 31 receptor A","Uniprot":["Q8NI17"],"Chromosome":"5","Position":"55851357-55922854","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Immunity"],"Molecular function":["Receptor"],"Disease involvement":["Amyloidosis","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"1.6","lymphoid tissue":"2.1","testis":"1.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"2.2","Late spermatids":"1.2","Spermatocytes":"2.5","Syncytiotrophoblasts":"1.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"0.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"GAMG":"26.3","HBEC3-KT":"10.3","HHSteC":"9.5","hTERT-HME1":"11.5","U-2 OS":"16.8","U-87 MG":"20.8"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebral cortex":"1.2"},"Antibody":["HPA051532","HPA068114"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA051532":null,"HPA068114":"AB_2732779"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"1.6","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.2","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"1.8","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"2.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"1.4","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"26.3","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"10.3","Cell RNA - HBF TERT88 [nTPM]":"2.2","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"9.5","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"7.3","Cell RNA - hTCEpi [nTPM]":"2.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.8","Cell RNA - hTERT-HME1 [nTPM]":"11.5","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"4.1","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"1.4","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"1.2","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"6.8","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"1.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"1.8","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"3.5","Cell RNA - TIME [nTPM]":"2.0","Cell RNA - U-138 MG [nTPM]":"0.5","Cell RNA - U-2 OS [nTPM]":"16.8","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.8","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"20.8","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"2.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"2.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"IL36RN","Gene synonym":["FIL1","FIL1(DELTA)","FIL1D","IL-1F5","IL1F5","IL1HY1","IL1L1","IL1RP3","IL36RA","MGC29840"],"Ensembl":"ENSG00000136695","Gene description":"Interleukin 36 receptor antagonist","Uniprot":["Q9UBH0"],"Chromosome":"2","Position":"113058638-113065382","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":["Cytokine"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"esophagus":"26.5","lymphoid tissue":"43.7","skin 1":"60.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"8.9","Extravillous trophoblasts":"2.0","Syncytiotrophoblasts":"3.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"head and neck cancer":"25.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"13","RNA cell line specific nTPM":{"BEWO":"26.6","GAMG":"11.1","U-87 MG":"19.9"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":107000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"2.4","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"2.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"26.5","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"1.4","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"3.4","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"4.6","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"60.3","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"43.7","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"9.1","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"1.4","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"26.6","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"1.1","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"11.1","Cell RNA - HaCaT [nTPM]":"1.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.5","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.9","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.6","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"19.9","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.9","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.6","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.8","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"IL4R","Gene synonym":["CD124"],"Ensembl":"ENSG00000077238","Gene description":"Interleukin 4 receptor","Uniprot":["P24394"],"Chromosome":"16","Position":"27313668-27364778","Protein class":["Cancer-related genes","CD markers","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","Transporters"],"Biological process":["Immunity"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"92.0","granulocytes":"110.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"78.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"78.1","granulocytes":"31.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"124.2","HBEC3-KT":"115.0","HDLM-2":"110.6","U-698":"119.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004451","HPA050124","HPA070380"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Centriolar satellite"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":38500,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":["Centriolar satellite"],"Antibody RRID":{"CAB004451":"AB_626889","HPA050124":"AB_2681026","HPA070380":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.43e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.23e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.58e-2"},"Tissue RNA - adipose tissue [nTPM]":"49.4","Tissue RNA - adrenal gland [nTPM]":"45.2","Tissue RNA - amygdala [nTPM]":"22.7","Tissue RNA - appendix [nTPM]":"82.3","Tissue RNA - basal ganglia [nTPM]":"19.7","Tissue RNA - bone marrow [nTPM]":"103.4","Tissue RNA - breast [nTPM]":"34.1","Tissue RNA - cerebellum [nTPM]":"19.2","Tissue RNA - cerebral cortex [nTPM]":"22.0","Tissue RNA - cervix [nTPM]":"39.7","Tissue RNA - choroid plexus [nTPM]":"21.4","Tissue RNA - colon [nTPM]":"97.0","Tissue RNA - duodenum [nTPM]":"27.3","Tissue RNA - endometrium 1 [nTPM]":"35.8","Tissue RNA - epididymis [nTPM]":"5.9","Tissue RNA - esophagus [nTPM]":"70.8","Tissue RNA - fallopian tube [nTPM]":"42.3","Tissue RNA - gallbladder [nTPM]":"41.2","Tissue RNA - heart muscle [nTPM]":"34.2","Tissue RNA - hippocampal formation [nTPM]":"18.7","Tissue RNA - hypothalamus [nTPM]":"21.0","Tissue RNA - kidney [nTPM]":"50.8","Tissue RNA - liver [nTPM]":"116.0","Tissue RNA - lung [nTPM]":"119.2","Tissue RNA - lymph node [nTPM]":"117.1","Tissue RNA - medulla oblongata [nTPM]":"29.4","Tissue RNA - midbrain [nTPM]":"22.2","Tissue RNA - ovary [nTPM]":"14.3","Tissue RNA - pancreas [nTPM]":"29.8","Tissue RNA - parathyroid gland [nTPM]":"31.7","Tissue RNA - pituitary gland [nTPM]":"14.9","Tissue RNA - placenta [nTPM]":"39.3","Tissue RNA - pons [nTPM]":"24.0","Tissue RNA - prostate [nTPM]":"49.9","Tissue RNA - rectum [nTPM]":"35.6","Tissue RNA - retina [nTPM]":"2.4","Tissue RNA - salivary gland [nTPM]":"20.5","Tissue RNA - seminal vesicle [nTPM]":"25.6","Tissue RNA - skeletal muscle [nTPM]":"9.3","Tissue RNA - skin 1 [nTPM]":"24.4","Tissue RNA - small intestine [nTPM]":"55.7","Tissue RNA - smooth muscle [nTPM]":"37.3","Tissue RNA - spinal cord [nTPM]":"25.5","Tissue RNA - spleen [nTPM]":"90.0","Tissue RNA - stomach 1 [nTPM]":"55.0","Tissue RNA - testis [nTPM]":"15.5","Tissue RNA - thalamus [nTPM]":"25.3","Tissue RNA - thymus [nTPM]":"22.3","Tissue RNA - thyroid gland [nTPM]":"24.2","Tissue RNA - tongue [nTPM]":"6.6","Tissue RNA - tonsil [nTPM]":"89.6","Tissue RNA - urinary bladder [nTPM]":"63.2","Tissue RNA - vagina [nTPM]":"45.4","Tissue RNA - white matter [nTPM]":"23.8","Cell RNA - A-431 [nTPM]":"39.9","Cell RNA - A549 [nTPM]":"10.1","Cell RNA - AF22 [nTPM]":"6.4","Cell RNA - AN3-CA [nTPM]":"13.1","Cell RNA - ASC diff [nTPM]":"3.1","Cell RNA - ASC TERT1 [nTPM]":"14.1","Cell RNA - BEWO [nTPM]":"14.3","Cell RNA - BJ [nTPM]":"24.7","Cell RNA - BJ hTERT+ [nTPM]":"27.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.7","Cell RNA - CACO-2 [nTPM]":"20.4","Cell RNA - CAPAN-2 [nTPM]":"105.2","Cell RNA - Daudi [nTPM]":"124.2","Cell RNA - EFO-21 [nTPM]":"30.1","Cell RNA - fHDF\/TERT166 [nTPM]":"38.5","Cell RNA - GAMG [nTPM]":"18.3","Cell RNA - HaCaT [nTPM]":"39.7","Cell RNA - HAP1 [nTPM]":"7.3","Cell RNA - HBEC3-KT [nTPM]":"115.0","Cell RNA - HBF TERT88 [nTPM]":"8.2","Cell RNA - HDLM-2 [nTPM]":"110.6","Cell RNA - HEK 293 [nTPM]":"4.0","Cell RNA - HEL [nTPM]":"22.6","Cell RNA - HeLa [nTPM]":"6.6","Cell RNA - Hep G2 [nTPM]":"31.6","Cell RNA - HHSteC [nTPM]":"40.8","Cell RNA - HL-60 [nTPM]":"6.1","Cell RNA - HMC-1 [nTPM]":"61.7","Cell RNA - HSkMC [nTPM]":"23.5","Cell RNA - hTCEpi [nTPM]":"45.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"44.2","Cell RNA - hTERT-HME1 [nTPM]":"26.5","Cell RNA - hTERT-RPE1 [nTPM]":"48.7","Cell RNA - HUVEC TERT2 [nTPM]":"50.7","Cell RNA - JURKAT [nTPM]":"6.8","Cell RNA - K-562 [nTPM]":"10.5","Cell RNA - Karpas-707 [nTPM]":"9.8","Cell RNA - LHCN-M2 [nTPM]":"15.0","Cell RNA - MCF7 [nTPM]":"17.3","Cell RNA - MOLT-4 [nTPM]":"0.7","Cell RNA - NB-4 [nTPM]":"18.8","Cell RNA - NTERA-2 [nTPM]":"8.0","Cell RNA - OE19 [nTPM]":"34.2","Cell RNA - PC-3 [nTPM]":"9.1","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"47.5","Cell RNA - RPMI-8226 [nTPM]":"10.2","Cell RNA - RPTEC TERT1 [nTPM]":"42.9","Cell RNA - RT4 [nTPM]":"43.2","Cell RNA - SCLC-21H [nTPM]":"1.9","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"3.7","Cell RNA - SK-BR-3 [nTPM]":"24.7","Cell RNA - SK-MEL-30 [nTPM]":"5.0","Cell RNA - SuSa [nTPM]":"15.6","Cell RNA - T-47d [nTPM]":"8.2","Cell RNA - THP-1 [nTPM]":"23.5","Cell RNA - TIME [nTPM]":"81.0","Cell RNA - U-138 MG [nTPM]":"21.0","Cell RNA - U-2 OS [nTPM]":"9.8","Cell RNA - U-2197 [nTPM]":"19.0","Cell RNA - U-251 MG [nTPM]":"17.6","Cell RNA - U-266\/70 [nTPM]":"6.1","Cell RNA - U-266\/84 [nTPM]":"2.1","Cell RNA - U-698 [nTPM]":"119.7","Cell RNA - U-87 MG [nTPM]":"2.1","Cell RNA - U-937 [nTPM]":"21.1","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"1.4","Blood RNA - classical monocyte [nTPM]":"7.2","Blood RNA - eosinophil [nTPM]":"13.0","Blood RNA - gdT-cell [nTPM]":"4.2","Blood RNA - intermediate monocyte [nTPM]":"3.1","Blood RNA - MAIT T-cell [nTPM]":"3.4","Blood RNA - memory B-cell [nTPM]":"25.8","Blood RNA - memory CD4 T-cell [nTPM]":"6.9","Blood RNA - memory CD8 T-cell [nTPM]":"4.4","Blood RNA - myeloid DC [nTPM]":"4.1","Blood RNA - naive B-cell [nTPM]":"78.1","Blood RNA - naive CD4 T-cell [nTPM]":"10.0","Blood RNA - naive CD8 T-cell [nTPM]":"5.0","Blood RNA - neutrophil [nTPM]":"31.1","Blood RNA - NK-cell [nTPM]":"8.2","Blood RNA - non-classical monocyte [nTPM]":"1.8","Blood RNA - plasmacytoid DC [nTPM]":"4.8","Blood RNA - T-reg [nTPM]":"5.3","Blood RNA - total PBMC [nTPM]":"5.8","Brain RNA - amygdala [nTPM]":"22.7","Brain RNA - basal ganglia [nTPM]":"19.7","Brain RNA - cerebellum [nTPM]":"19.2","Brain RNA - cerebral cortex [nTPM]":"22.0","Brain RNA - hippocampal formation [nTPM]":"18.7","Brain RNA - hypothalamus [nTPM]":"21.0","Brain RNA - medulla oblongata [nTPM]":"29.4","Brain RNA - midbrain [nTPM]":"22.2","Brain RNA - pons [nTPM]":"24.0","Brain RNA - spinal cord [nTPM]":"25.5","Brain RNA - thalamus [nTPM]":"25.3","Brain RNA - white matter [nTPM]":"23.8","Single Cell Type RNA - Adipocytes [nTPM]":"30.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"49.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"92.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"43.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"34.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"33.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.6","Single Cell Type RNA - dendritic cells [nTPM]":"29.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"60.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"39.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.2","Single Cell Type RNA - Endothelial cells [nTPM]":"39.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"23.4","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.8","Single Cell Type RNA - Fibroblasts [nTPM]":"17.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.2","Single Cell Type RNA - granulocytes [nTPM]":"110.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"62.8","Single Cell Type RNA - Hepatocytes [nTPM]":"45.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"27.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"35.5","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"30.6","Single Cell Type RNA - Langerhans cells [nTPM]":"29.9","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"34.3","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"38.4","Single Cell Type RNA - monocytes [nTPM]":"39.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"49.3","Single Cell Type RNA - Paneth cells [nTPM]":"28.7","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"13.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"37.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"24.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"3.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"24.9","Single Cell Type RNA - T-cells [nTPM]":"38.3","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.7","Single Cell Type RNA - Urothelial cells [nTPM]":"46.9"},{"Gene":"IL7","Gene synonym":["IL-7"],"Ensembl":"ENSG00000104432","Gene description":"Interleukin 7","Uniprot":["P13232"],"Chromosome":"8","Position":"78675743-78805523","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Cytokine","Growth factor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"108.8","Late spermatids":"145.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"memory B-cell":"9.7","naive B-cell":"8.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"7.6","HDLM-2":"15.4","HEL":"18.2","HMC-1":"25.4"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019590"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":60700,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA019590":"AB_10794621"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.57e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.37e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.69e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-4"},"Tissue RNA - adipose tissue [nTPM]":"2.3","Tissue RNA - adrenal gland [nTPM]":"1.2","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"4.1","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"2.1","Tissue RNA - breast [nTPM]":"1.5","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"2.3","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"5.1","Tissue RNA - duodenum [nTPM]":"6.7","Tissue RNA - endometrium 1 [nTPM]":"1.1","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"3.5","Tissue RNA - fallopian tube [nTPM]":"4.8","Tissue RNA - gallbladder [nTPM]":"3.1","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.5","Tissue RNA - kidney [nTPM]":"1.4","Tissue RNA - liver [nTPM]":"4.2","Tissue RNA - lung [nTPM]":"3.3","Tissue RNA - lymph node [nTPM]":"8.7","Tissue RNA - medulla oblongata [nTPM]":"0.6","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"1.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"1.8","Tissue RNA - rectum [nTPM]":"4.4","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"1.1","Tissue RNA - seminal vesicle [nTPM]":"0.9","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"8.8","Tissue RNA - small intestine [nTPM]":"8.7","Tissue RNA - smooth muscle [nTPM]":"1.1","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"3.5","Tissue RNA - stomach 1 [nTPM]":"3.8","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"1.3","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"4.2","Tissue RNA - urinary bladder [nTPM]":"2.8","Tissue RNA - vagina [nTPM]":"1.5","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.4","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"1.4","Cell RNA - BJ hTERT+ [nTPM]":"1.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.9","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"7.6","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"4.4","Cell RNA - GAMG [nTPM]":"4.5","Cell RNA - HaCaT [nTPM]":"4.2","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"15.4","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"18.2","Cell RNA - HeLa [nTPM]":"0.6","Cell RNA - Hep G2 [nTPM]":"2.1","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"25.4","Cell RNA - HSkMC [nTPM]":"1.3","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.6","Cell RNA - hTERT-RPE1 [nTPM]":"4.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"1.4","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"1.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"5.4","Cell RNA - RT4 [nTPM]":"3.2","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"2.4","Cell RNA - SiHa [nTPM]":"2.6","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.8","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"2.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"3.4","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.9","Blood RNA - basophil [nTPM]":"5.2","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"9.7","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.0","Blood RNA - myeloid DC [nTPM]":"2.2","Blood RNA - naive B-cell [nTPM]":"8.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.8","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"7.3","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.5","Brain RNA - medulla oblongata [nTPM]":"0.6","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.6","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"12.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"2.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"1.2","Single Cell Type RNA - Early spermatids [nTPM]":"108.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.8","Single Cell Type RNA - Endothelial cells [nTPM]":"4.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"10.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"2.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"2.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"3.3","Single Cell Type RNA - Late spermatids [nTPM]":"145.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"1.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"3.4","Single Cell Type RNA - Muller glia cells [nTPM]":"2.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"20.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.6","Single Cell Type RNA - Paneth cells [nTPM]":"11.5","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"1.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"24.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"2.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.6","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.6","Single Cell Type RNA - Urothelial cells [nTPM]":"1.7"},{"Gene":"IRAK2","Gene synonym":[],"Ensembl":"ENSG00000134070","Gene description":"Interleukin 1 receptor associated kinase 2","Uniprot":["O43187"],"Chromosome":"3","Position":"10164919-10243745","Protein class":["Enzymes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"23.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"43.7","Oligodendrocytes":"34.3","Prostatic glandular cells":"23.4","Urothelial cells":"30.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"33.2","BJ hTERT+":"35.2","CAPAN-2":"35.6","GAMG":"62.6","RT4":"49.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013483","HPA050520"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB013483":null,"HPA050520":"AB_2681154"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.35e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.26e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.60e-5"},"Tissue RNA - adipose tissue [nTPM]":"6.4","Tissue RNA - adrenal gland [nTPM]":"3.6","Tissue RNA - amygdala [nTPM]":"4.0","Tissue RNA - appendix [nTPM]":"6.0","Tissue RNA - basal ganglia [nTPM]":"3.9","Tissue RNA - bone marrow [nTPM]":"23.3","Tissue RNA - breast [nTPM]":"4.6","Tissue RNA - cerebellum [nTPM]":"3.9","Tissue RNA - cerebral cortex [nTPM]":"8.0","Tissue RNA - cervix [nTPM]":"2.9","Tissue RNA - choroid plexus [nTPM]":"1.7","Tissue RNA - colon [nTPM]":"2.1","Tissue RNA - duodenum [nTPM]":"2.0","Tissue RNA - endometrium 1 [nTPM]":"2.0","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"7.2","Tissue RNA - fallopian tube [nTPM]":"1.8","Tissue RNA - gallbladder [nTPM]":"4.4","Tissue RNA - heart muscle [nTPM]":"1.9","Tissue RNA - hippocampal formation [nTPM]":"3.2","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"3.4","Tissue RNA - liver [nTPM]":"10.8","Tissue RNA - lung [nTPM]":"10.4","Tissue RNA - lymph node [nTPM]":"3.8","Tissue RNA - medulla oblongata [nTPM]":"5.1","Tissue RNA - midbrain [nTPM]":"4.1","Tissue RNA - ovary [nTPM]":"1.0","Tissue RNA - pancreas [nTPM]":"1.9","Tissue RNA - parathyroid gland [nTPM]":"1.0","Tissue RNA - pituitary gland [nTPM]":"1.2","Tissue RNA - placenta [nTPM]":"2.2","Tissue RNA - pons [nTPM]":"5.6","Tissue RNA - prostate [nTPM]":"3.3","Tissue RNA - rectum [nTPM]":"1.7","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"3.6","Tissue RNA - seminal vesicle [nTPM]":"1.8","Tissue RNA - skeletal muscle [nTPM]":"17.0","Tissue RNA - skin 1 [nTPM]":"5.2","Tissue RNA - small intestine [nTPM]":"5.4","Tissue RNA - smooth muscle [nTPM]":"1.4","Tissue RNA - spinal cord [nTPM]":"3.4","Tissue RNA - spleen [nTPM]":"4.5","Tissue RNA - stomach 1 [nTPM]":"3.4","Tissue RNA - testis [nTPM]":"1.3","Tissue RNA - thalamus [nTPM]":"4.2","Tissue RNA - thymus [nTPM]":"3.9","Tissue RNA - thyroid gland [nTPM]":"3.1","Tissue RNA - tongue [nTPM]":"4.3","Tissue RNA - tonsil [nTPM]":"11.5","Tissue RNA - urinary bladder [nTPM]":"16.1","Tissue RNA - vagina [nTPM]":"4.5","Tissue RNA - white matter [nTPM]":"8.0","Cell RNA - A-431 [nTPM]":"2.7","Cell RNA - A549 [nTPM]":"7.6","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"1.0","Cell RNA - ASC diff [nTPM]":"8.1","Cell RNA - ASC TERT1 [nTPM]":"6.7","Cell RNA - BEWO [nTPM]":"33.2","Cell RNA - BJ [nTPM]":"2.9","Cell RNA - BJ hTERT+ [nTPM]":"35.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.5","Cell RNA - CACO-2 [nTPM]":"3.6","Cell RNA - CAPAN-2 [nTPM]":"35.6","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.9","Cell RNA - fHDF\/TERT166 [nTPM]":"4.3","Cell RNA - GAMG [nTPM]":"62.6","Cell RNA - HaCaT [nTPM]":"0.8","Cell RNA - HAP1 [nTPM]":"0.8","Cell RNA - HBEC3-KT [nTPM]":"9.0","Cell RNA - HBF TERT88 [nTPM]":"6.3","Cell RNA - HDLM-2 [nTPM]":"2.3","Cell RNA - HEK 293 [nTPM]":"2.5","Cell RNA - HEL [nTPM]":"0.8","Cell RNA - HeLa [nTPM]":"1.7","Cell RNA - Hep G2 [nTPM]":"9.9","Cell RNA - HHSteC [nTPM]":"3.9","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.1","Cell RNA - HSkMC [nTPM]":"4.1","Cell RNA - hTCEpi [nTPM]":"1.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.3","Cell RNA - hTERT-HME1 [nTPM]":"22.4","Cell RNA - hTERT-RPE1 [nTPM]":"12.4","Cell RNA - HUVEC TERT2 [nTPM]":"9.7","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"1.8","Cell RNA - Karpas-707 [nTPM]":"10.7","Cell RNA - LHCN-M2 [nTPM]":"5.7","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"1.8","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"4.2","Cell RNA - PC-3 [nTPM]":"7.5","Cell RNA - REH [nTPM]":"1.7","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"10.3","Cell RNA - RT4 [nTPM]":"49.2","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"3.3","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"0.8","Cell RNA - T-47d [nTPM]":"0.8","Cell RNA - THP-1 [nTPM]":"1.7","Cell RNA - TIME [nTPM]":"10.1","Cell RNA - U-138 MG [nTPM]":"10.7","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"6.5","Cell RNA - U-251 MG [nTPM]":"7.0","Cell RNA - U-266\/70 [nTPM]":"3.6","Cell RNA - U-266\/84 [nTPM]":"11.3","Cell RNA - U-698 [nTPM]":"2.1","Cell RNA - U-87 MG [nTPM]":"22.9","Cell RNA - U-937 [nTPM]":"4.7","Cell RNA - WM-115 [nTPM]":"1.9","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"1.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"5.8","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"6.0","Blood RNA - memory B-cell [nTPM]":"4.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.7","Blood RNA - memory CD8 T-cell [nTPM]":"3.3","Blood RNA - myeloid DC [nTPM]":"1.0","Blood RNA - naive B-cell [nTPM]":"3.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"3.0","Blood RNA - neutrophil [nTPM]":"2.1","Blood RNA - NK-cell [nTPM]":"7.4","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"2.2","Brain RNA - amygdala [nTPM]":"4.0","Brain RNA - basal ganglia [nTPM]":"3.9","Brain RNA - cerebellum [nTPM]":"3.9","Brain RNA - cerebral cortex [nTPM]":"8.0","Brain RNA - hippocampal formation [nTPM]":"3.2","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"5.1","Brain RNA - midbrain [nTPM]":"4.1","Brain RNA - pons [nTPM]":"5.6","Brain RNA - spinal cord [nTPM]":"3.4","Brain RNA - thalamus [nTPM]":"4.2","Brain RNA - white matter [nTPM]":"8.0","Single Cell Type RNA - Adipocytes [nTPM]":"3.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.1","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"8.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"6.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"3.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"9.8","Single Cell Type RNA - Early spermatids [nTPM]":"4.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.4","Single Cell Type RNA - Endothelial cells [nTPM]":"12.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"4.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"4.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.7","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"2.9","Single Cell Type RNA - Langerhans cells [nTPM]":"43.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"20.9","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"1.9","Single Cell Type RNA - Muller glia cells [nTPM]":"2.1","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"34.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"7.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"3.9","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.5","Single Cell Type RNA - Urothelial cells [nTPM]":"30.4"},{"Gene":"IRF5","Gene synonym":[],"Ensembl":"ENSG00000128604","Gene description":"Interferon regulatory factor 5","Uniprot":["Q13568"],"Chromosome":"7","Position":"128937457-128950038","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Antiviral defense","Immunity","Inflammatory response","Innate immunity","Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Systemic lupus erythematosus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"20.2","Hofbauer cells":"38.4","Kupffer cells":"34.5","Macrophages":"27.8","monocytes":"76.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"17.6","dendritic cells":"43.6","monocytes":"53.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"124.3","RPMI-8226":"91.9","THP-1":"50.0","U-937":"62.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046700","HPA076024"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 3: Monocytes - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA046700":"AB_2679761","HPA076024":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-3"},"Tissue RNA - adipose tissue [nTPM]":"5.5","Tissue RNA - adrenal gland [nTPM]":"3.5","Tissue RNA - amygdala [nTPM]":"4.8","Tissue RNA - appendix [nTPM]":"13.1","Tissue RNA - basal ganglia [nTPM]":"3.9","Tissue RNA - bone marrow [nTPM]":"20.6","Tissue RNA - breast [nTPM]":"3.2","Tissue RNA - cerebellum [nTPM]":"4.9","Tissue RNA - cerebral cortex [nTPM]":"5.2","Tissue RNA - cervix [nTPM]":"3.2","Tissue RNA - choroid plexus [nTPM]":"3.9","Tissue RNA - colon [nTPM]":"4.4","Tissue RNA - duodenum [nTPM]":"9.5","Tissue RNA - endometrium 1 [nTPM]":"1.6","Tissue RNA - epididymis [nTPM]":"3.0","Tissue RNA - esophagus [nTPM]":"12.6","Tissue RNA - fallopian tube [nTPM]":"4.5","Tissue RNA - gallbladder [nTPM]":"6.3","Tissue RNA - heart muscle [nTPM]":"1.8","Tissue RNA - hippocampal formation [nTPM]":"4.3","Tissue RNA - hypothalamus [nTPM]":"6.4","Tissue RNA - kidney [nTPM]":"13.5","Tissue RNA - liver [nTPM]":"5.1","Tissue RNA - lung [nTPM]":"10.6","Tissue RNA - lymph node [nTPM]":"16.2","Tissue RNA - medulla oblongata [nTPM]":"8.7","Tissue RNA - midbrain [nTPM]":"6.3","Tissue RNA - ovary [nTPM]":"1.0","Tissue RNA - pancreas [nTPM]":"5.9","Tissue RNA - parathyroid gland [nTPM]":"6.4","Tissue RNA - pituitary gland [nTPM]":"5.2","Tissue RNA - placenta [nTPM]":"3.9","Tissue RNA - pons [nTPM]":"7.4","Tissue RNA - prostate [nTPM]":"3.3","Tissue RNA - rectum [nTPM]":"3.6","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"6.8","Tissue RNA - seminal vesicle [nTPM]":"12.7","Tissue RNA - skeletal muscle [nTPM]":"0.8","Tissue RNA - skin 1 [nTPM]":"8.6","Tissue RNA - small intestine [nTPM]":"11.2","Tissue RNA - smooth muscle [nTPM]":"3.1","Tissue RNA - spinal cord [nTPM]":"7.6","Tissue RNA - spleen [nTPM]":"24.0","Tissue RNA - stomach 1 [nTPM]":"4.6","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"7.9","Tissue RNA - thymus [nTPM]":"4.2","Tissue RNA - thyroid gland [nTPM]":"2.2","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"11.8","Tissue RNA - urinary bladder [nTPM]":"6.5","Tissue RNA - vagina [nTPM]":"5.8","Tissue RNA - white matter [nTPM]":"11.3","Cell RNA - A-431 [nTPM]":"13.9","Cell RNA - A549 [nTPM]":"4.6","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"1.4","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.9","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"5.7","Cell RNA - Daudi [nTPM]":"10.8","Cell RNA - EFO-21 [nTPM]":"5.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"12.1","Cell RNA - HaCaT [nTPM]":"12.9","Cell RNA - HAP1 [nTPM]":"3.4","Cell RNA - HBEC3-KT [nTPM]":"2.6","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"124.3","Cell RNA - HEK 293 [nTPM]":"2.9","Cell RNA - HEL [nTPM]":"18.3","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"1.9","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"2.7","Cell RNA - HMC-1 [nTPM]":"25.4","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"15.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.3","Cell RNA - hTERT-HME1 [nTPM]":"1.8","Cell RNA - hTERT-RPE1 [nTPM]":"1.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"31.5","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"5.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"4.8","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"1.7","Cell RNA - PC-3 [nTPM]":"2.6","Cell RNA - REH [nTPM]":"0.8","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"91.9","Cell RNA - RPTEC TERT1 [nTPM]":"3.8","Cell RNA - RT4 [nTPM]":"8.1","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"2.0","Cell RNA - SiHa [nTPM]":"2.7","Cell RNA - SK-BR-3 [nTPM]":"3.0","Cell RNA - SK-MEL-30 [nTPM]":"1.4","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"4.8","Cell RNA - THP-1 [nTPM]":"50.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"1.2","Cell RNA - U-266\/70 [nTPM]":"19.4","Cell RNA - U-266\/84 [nTPM]":"13.5","Cell RNA - U-698 [nTPM]":"4.5","Cell RNA - U-87 MG [nTPM]":"0.5","Cell RNA - U-937 [nTPM]":"62.6","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"1.8","Blood RNA - classical monocyte [nTPM]":"42.7","Blood RNA - eosinophil [nTPM]":"4.2","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"53.1","Blood RNA - MAIT T-cell [nTPM]":"4.0","Blood RNA - memory B-cell [nTPM]":"17.6","Blood RNA - memory CD4 T-cell [nTPM]":"2.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"43.6","Blood RNA - naive B-cell [nTPM]":"15.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"2.9","Blood RNA - NK-cell [nTPM]":"4.9","Blood RNA - non-classical monocyte [nTPM]":"38.0","Blood RNA - plasmacytoid DC [nTPM]":"10.4","Blood RNA - T-reg [nTPM]":"6.2","Blood RNA - total PBMC [nTPM]":"22.7","Brain RNA - amygdala [nTPM]":"4.8","Brain RNA - basal ganglia [nTPM]":"3.9","Brain RNA - cerebellum [nTPM]":"4.9","Brain RNA - cerebral cortex [nTPM]":"5.2","Brain RNA - hippocampal formation [nTPM]":"4.3","Brain RNA - hypothalamus [nTPM]":"6.4","Brain RNA - medulla oblongata [nTPM]":"8.7","Brain RNA - midbrain [nTPM]":"6.3","Brain RNA - pons [nTPM]":"7.4","Brain RNA - spinal cord [nTPM]":"7.6","Brain RNA - thalamus [nTPM]":"7.9","Brain RNA - white matter [nTPM]":"11.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"12.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"2.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"7.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"6.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.6","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"38.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"34.5","Single Cell Type RNA - Langerhans cells [nTPM]":"16.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"27.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"76.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.3","Single Cell Type RNA - Paneth cells [nTPM]":"1.7","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"9.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"3.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.5","Single Cell Type RNA - Urothelial cells [nTPM]":"2.1"},{"Gene":"ITPR2","Gene synonym":["CFAP48","IP3R2"],"Ensembl":"ENSG00000123104","Gene description":"Inositol 1,4,5-trisphosphate receptor type 2","Uniprot":["Q14571"],"Chromosome":"12","Position":"26335352-26833194","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Calcium transport","Ion transport","Transport"],"Molecular function":["Calcium channel","Ion channel","Ligand-gated ion channel","Receptor"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"44.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"551.4","Excitatory neurons":"287.2","Microglial cells":"802.9","Oligodendrocyte precursor cells":"441.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"32.4"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"TIME":"62.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059144","HPA062260"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA059144":"AB_2683925","HPA062260":"AB_2684728"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-1"},"Tissue RNA - adipose tissue [nTPM]":"8.3","Tissue RNA - adrenal gland [nTPM]":"10.4","Tissue RNA - amygdala [nTPM]":"10.5","Tissue RNA - appendix [nTPM]":"8.1","Tissue RNA - basal ganglia [nTPM]":"7.3","Tissue RNA - bone marrow [nTPM]":"6.0","Tissue RNA - breast [nTPM]":"17.3","Tissue RNA - cerebellum [nTPM]":"6.3","Tissue RNA - cerebral cortex [nTPM]":"9.7","Tissue RNA - cervix [nTPM]":"4.8","Tissue RNA - choroid plexus [nTPM]":"3.4","Tissue RNA - colon [nTPM]":"6.2","Tissue RNA - duodenum [nTPM]":"5.3","Tissue RNA - endometrium 1 [nTPM]":"5.2","Tissue RNA - epididymis [nTPM]":"5.7","Tissue RNA - esophagus [nTPM]":"7.4","Tissue RNA - fallopian tube [nTPM]":"5.5","Tissue RNA - gallbladder [nTPM]":"5.5","Tissue RNA - heart muscle [nTPM]":"3.7","Tissue RNA - hippocampal formation [nTPM]":"7.7","Tissue RNA - hypothalamus [nTPM]":"8.7","Tissue RNA - kidney [nTPM]":"12.6","Tissue RNA - liver [nTPM]":"44.3","Tissue RNA - lung [nTPM]":"5.6","Tissue RNA - lymph node [nTPM]":"7.9","Tissue RNA - medulla oblongata [nTPM]":"19.1","Tissue RNA - midbrain [nTPM]":"13.2","Tissue RNA - ovary [nTPM]":"5.9","Tissue RNA - pancreas [nTPM]":"7.7","Tissue RNA - parathyroid gland [nTPM]":"11.4","Tissue RNA - pituitary gland [nTPM]":"2.2","Tissue RNA - placenta [nTPM]":"10.9","Tissue RNA - pons [nTPM]":"14.9","Tissue RNA - prostate [nTPM]":"5.5","Tissue RNA - rectum [nTPM]":"6.6","Tissue RNA - retina [nTPM]":"8.8","Tissue RNA - salivary gland [nTPM]":"16.9","Tissue RNA - seminal vesicle [nTPM]":"2.9","Tissue RNA - skeletal muscle [nTPM]":"1.8","Tissue RNA - skin 1 [nTPM]":"10.2","Tissue RNA - small intestine [nTPM]":"4.9","Tissue RNA - smooth muscle [nTPM]":"4.5","Tissue RNA - spinal cord [nTPM]":"13.1","Tissue RNA - spleen [nTPM]":"6.7","Tissue RNA - stomach 1 [nTPM]":"5.2","Tissue RNA - testis [nTPM]":"2.5","Tissue RNA - thalamus [nTPM]":"16.1","Tissue RNA - thymus [nTPM]":"20.1","Tissue RNA - thyroid gland [nTPM]":"4.3","Tissue RNA - tongue [nTPM]":"4.1","Tissue RNA - tonsil [nTPM]":"6.8","Tissue RNA - urinary bladder [nTPM]":"4.9","Tissue RNA - vagina [nTPM]":"4.7","Tissue RNA - white matter [nTPM]":"15.6","Cell RNA - A-431 [nTPM]":"4.9","Cell RNA - A549 [nTPM]":"2.0","Cell RNA - AF22 [nTPM]":"2.9","Cell RNA - AN3-CA [nTPM]":"4.6","Cell RNA - ASC diff [nTPM]":"8.5","Cell RNA - ASC TERT1 [nTPM]":"8.6","Cell RNA - BEWO [nTPM]":"3.0","Cell RNA - BJ [nTPM]":"4.4","Cell RNA - BJ hTERT+ [nTPM]":"6.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.1","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"2.4","Cell RNA - Daudi [nTPM]":"16.5","Cell RNA - EFO-21 [nTPM]":"2.7","Cell RNA - fHDF\/TERT166 [nTPM]":"5.9","Cell RNA - GAMG [nTPM]":"3.3","Cell RNA - HaCaT [nTPM]":"5.2","Cell RNA - HAP1 [nTPM]":"15.1","Cell RNA - HBEC3-KT [nTPM]":"9.3","Cell RNA - HBF TERT88 [nTPM]":"4.0","Cell RNA - HDLM-2 [nTPM]":"3.9","Cell RNA - HEK 293 [nTPM]":"5.1","Cell RNA - HEL [nTPM]":"13.5","Cell RNA - HeLa [nTPM]":"4.4","Cell RNA - Hep G2 [nTPM]":"27.1","Cell RNA - HHSteC [nTPM]":"7.9","Cell RNA - HL-60 [nTPM]":"12.0","Cell RNA - HMC-1 [nTPM]":"5.8","Cell RNA - HSkMC [nTPM]":"8.1","Cell RNA - hTCEpi [nTPM]":"1.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.3","Cell RNA - hTERT-HME1 [nTPM]":"11.6","Cell RNA - hTERT-RPE1 [nTPM]":"6.2","Cell RNA - HUVEC TERT2 [nTPM]":"28.5","Cell RNA - JURKAT [nTPM]":"6.5","Cell RNA - K-562 [nTPM]":"6.4","Cell RNA - Karpas-707 [nTPM]":"5.1","Cell RNA - LHCN-M2 [nTPM]":"3.9","Cell RNA - MCF7 [nTPM]":"4.0","Cell RNA - MOLT-4 [nTPM]":"8.6","Cell RNA - NB-4 [nTPM]":"17.8","Cell RNA - NTERA-2 [nTPM]":"12.2","Cell RNA - OE19 [nTPM]":"4.4","Cell RNA - PC-3 [nTPM]":"1.5","Cell RNA - REH [nTPM]":"2.9","Cell RNA - RH-30 [nTPM]":"7.0","Cell RNA - RPMI-8226 [nTPM]":"10.7","Cell RNA - RPTEC TERT1 [nTPM]":"7.3","Cell RNA - RT4 [nTPM]":"7.4","Cell RNA - SCLC-21H [nTPM]":"0.9","Cell RNA - SH-SY5Y [nTPM]":"4.5","Cell RNA - SiHa [nTPM]":"19.8","Cell RNA - SK-BR-3 [nTPM]":"3.5","Cell RNA - SK-MEL-30 [nTPM]":"11.4","Cell RNA - SuSa [nTPM]":"11.3","Cell RNA - T-47d [nTPM]":"7.7","Cell RNA - THP-1 [nTPM]":"6.0","Cell RNA - TIME [nTPM]":"62.6","Cell RNA - U-138 MG [nTPM]":"6.0","Cell RNA - U-2 OS [nTPM]":"2.3","Cell RNA - U-2197 [nTPM]":"5.9","Cell RNA - U-251 MG [nTPM]":"5.7","Cell RNA - U-266\/70 [nTPM]":"4.9","Cell RNA - U-266\/84 [nTPM]":"4.2","Cell RNA - U-698 [nTPM]":"31.2","Cell RNA - U-87 MG [nTPM]":"5.7","Cell RNA - U-937 [nTPM]":"5.6","Cell RNA - WM-115 [nTPM]":"3.9","Blood RNA - basophil [nTPM]":"32.4","Blood RNA - classical monocyte [nTPM]":"6.4","Blood RNA - eosinophil [nTPM]":"9.9","Blood RNA - gdT-cell [nTPM]":"2.9","Blood RNA - intermediate monocyte [nTPM]":"2.7","Blood RNA - MAIT T-cell [nTPM]":"2.5","Blood RNA - memory B-cell [nTPM]":"5.4","Blood RNA - memory CD4 T-cell [nTPM]":"2.6","Blood RNA - memory CD8 T-cell [nTPM]":"2.4","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"5.0","Blood RNA - naive CD4 T-cell [nTPM]":"3.0","Blood RNA - naive CD8 T-cell [nTPM]":"2.7","Blood RNA - neutrophil [nTPM]":"17.3","Blood RNA - NK-cell [nTPM]":"4.8","Blood RNA - non-classical monocyte [nTPM]":"4.3","Blood RNA - plasmacytoid DC [nTPM]":"11.9","Blood RNA - T-reg [nTPM]":"4.4","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"10.5","Brain RNA - basal ganglia [nTPM]":"7.3","Brain RNA - cerebellum [nTPM]":"6.3","Brain RNA - cerebral cortex [nTPM]":"9.7","Brain RNA - hippocampal formation [nTPM]":"7.7","Brain RNA - hypothalamus [nTPM]":"8.7","Brain RNA - medulla oblongata [nTPM]":"19.1","Brain RNA - midbrain [nTPM]":"13.2","Brain RNA - pons [nTPM]":"14.9","Brain RNA - spinal cord [nTPM]":"13.1","Brain RNA - thalamus [nTPM]":"16.1","Brain RNA - white matter [nTPM]":"15.6","Single Cell Type RNA - Adipocytes [nTPM]":"27.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"52.9","Single Cell Type RNA - Astrocytes [nTPM]":"551.4","Single Cell Type RNA - B-cells [nTPM]":"45.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.3","Single Cell Type RNA - Bipolar cells [nTPM]":"3.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"87.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"57.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"24.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"8.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"146.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.0","Single Cell Type RNA - dendritic cells [nTPM]":"39.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"20.8","Single Cell Type RNA - Early spermatids [nTPM]":"3.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"64.9","Single Cell Type RNA - Endothelial cells [nTPM]":"38.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"78.5","Single Cell Type RNA - Erythroid cells [nTPM]":"33.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"287.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.5","Single Cell Type RNA - Fibroblasts [nTPM]":"20.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"22.7","Single Cell Type RNA - granulocytes [nTPM]":"44.4","Single Cell Type RNA - Granulosa cells [nTPM]":"60.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.0","Single Cell Type RNA - Hepatocytes [nTPM]":"123.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"39.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"99.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"46.1","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"46.3","Single Cell Type RNA - Langerhans cells [nTPM]":"8.2","Single Cell Type RNA - Late spermatids [nTPM]":"6.7","Single Cell Type RNA - Leydig cells [nTPM]":"18.0","Single Cell Type RNA - Macrophages [nTPM]":"68.7","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"802.9","Single Cell Type RNA - monocytes [nTPM]":"28.2","Single Cell Type RNA - Muller glia cells [nTPM]":"13.0","Single Cell Type RNA - NK-cells [nTPM]":"41.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"441.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"22.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.6","Single Cell Type RNA - Paneth cells [nTPM]":"37.0","Single Cell Type RNA - Peritubular cells [nTPM]":"17.7","Single Cell Type RNA - Plasma cells [nTPM]":"83.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"25.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"64.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.6","Single Cell Type RNA - Spermatocytes [nTPM]":"3.6","Single Cell Type RNA - Spermatogonia [nTPM]":"6.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"54.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"26.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.9","Single Cell Type RNA - T-cells [nTPM]":"29.2","Single Cell Type RNA - Theca cells [nTPM]":"43.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.7","Single Cell Type RNA - Urothelial cells [nTPM]":"15.8"},{"Gene":"KITLG","Gene synonym":["DFNA69","FPH2","Kitl","KL-1","MGF","SCF","SF","SLF"],"Ensembl":"ENSG00000049130","Gene description":"KIT ligand","Uniprot":["P21583"],"Chromosome":"12","Position":"88492793-88580851","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Growth factor"],"Disease involvement":["Cancer-related genes","Deafness","Disease variant","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"83.6","Collecting duct cells":"69.9","Excitatory neurons":"46.5","Inhibitory neurons":"61.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"299.8","SK-BR-3":"118.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA070395"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"260000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA070395":"AB_2686264"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.01e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.61e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.81e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Tissue RNA - adipose tissue [nTPM]":"13.2","Tissue RNA - adrenal gland [nTPM]":"3.9","Tissue RNA - amygdala [nTPM]":"2.3","Tissue RNA - appendix [nTPM]":"8.2","Tissue RNA - basal ganglia [nTPM]":"3.5","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"10.6","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"3.1","Tissue RNA - cervix [nTPM]":"12.9","Tissue RNA - choroid plexus [nTPM]":"1.2","Tissue RNA - colon [nTPM]":"18.7","Tissue RNA - duodenum [nTPM]":"9.6","Tissue RNA - endometrium 1 [nTPM]":"15.1","Tissue RNA - epididymis [nTPM]":"2.8","Tissue RNA - esophagus [nTPM]":"14.3","Tissue RNA - fallopian tube [nTPM]":"4.0","Tissue RNA - gallbladder [nTPM]":"18.5","Tissue RNA - heart muscle [nTPM]":"7.0","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"0.3","Tissue RNA - kidney [nTPM]":"16.0","Tissue RNA - liver [nTPM]":"2.3","Tissue RNA - lung [nTPM]":"31.6","Tissue RNA - lymph node [nTPM]":"3.3","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"2.5","Tissue RNA - ovary [nTPM]":"6.0","Tissue RNA - pancreas [nTPM]":"3.7","Tissue RNA - parathyroid gland [nTPM]":"3.7","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"15.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"15.1","Tissue RNA - rectum [nTPM]":"22.6","Tissue RNA - retina [nTPM]":"2.3","Tissue RNA - salivary gland [nTPM]":"8.8","Tissue RNA - seminal vesicle [nTPM]":"14.8","Tissue RNA - skeletal muscle [nTPM]":"3.1","Tissue RNA - skin 1 [nTPM]":"7.1","Tissue RNA - small intestine [nTPM]":"11.6","Tissue RNA - smooth muscle [nTPM]":"18.8","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"3.5","Tissue RNA - stomach 1 [nTPM]":"17.4","Tissue RNA - testis [nTPM]":"6.3","Tissue RNA - thalamus [nTPM]":"5.2","Tissue RNA - thymus [nTPM]":"5.1","Tissue RNA - thyroid gland [nTPM]":"5.9","Tissue RNA - tongue [nTPM]":"14.4","Tissue RNA - tonsil [nTPM]":"10.4","Tissue RNA - urinary bladder [nTPM]":"12.3","Tissue RNA - vagina [nTPM]":"1.3","Tissue RNA - white matter [nTPM]":"6.2","Cell RNA - A-431 [nTPM]":"14.3","Cell RNA - A549 [nTPM]":"7.1","Cell RNA - AF22 [nTPM]":"7.1","Cell RNA - AN3-CA [nTPM]":"0.9","Cell RNA - ASC diff [nTPM]":"29.0","Cell RNA - ASC TERT1 [nTPM]":"61.5","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"77.6","Cell RNA - BJ hTERT+ [nTPM]":"60.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.4","Cell RNA - CACO-2 [nTPM]":"299.8","Cell RNA - CAPAN-2 [nTPM]":"11.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"2.2","Cell RNA - fHDF\/TERT166 [nTPM]":"73.3","Cell RNA - GAMG [nTPM]":"14.9","Cell RNA - HaCaT [nTPM]":"49.5","Cell RNA - HAP1 [nTPM]":"11.5","Cell RNA - HBEC3-KT [nTPM]":"20.1","Cell RNA - HBF TERT88 [nTPM]":"14.2","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"9.5","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"9.5","Cell RNA - Hep G2 [nTPM]":"2.6","Cell RNA - HHSteC [nTPM]":"4.4","Cell RNA - HL-60 [nTPM]":"1.9","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"53.5","Cell RNA - hTCEpi [nTPM]":"20.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"41.6","Cell RNA - hTERT-HME1 [nTPM]":"26.8","Cell RNA - hTERT-RPE1 [nTPM]":"6.3","Cell RNA - HUVEC TERT2 [nTPM]":"17.9","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"6.8","Cell RNA - MCF7 [nTPM]":"2.5","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"4.8","Cell RNA - OE19 [nTPM]":"17.7","Cell RNA - PC-3 [nTPM]":"17.9","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"12.6","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"25.0","Cell RNA - RT4 [nTPM]":"6.5","Cell RNA - SCLC-21H [nTPM]":"2.3","Cell RNA - SH-SY5Y [nTPM]":"4.8","Cell RNA - SiHa [nTPM]":"18.5","Cell RNA - SK-BR-3 [nTPM]":"118.9","Cell RNA - SK-MEL-30 [nTPM]":"2.2","Cell RNA - SuSa [nTPM]":"6.5","Cell RNA - T-47d [nTPM]":"57.2","Cell RNA - THP-1 [nTPM]":"4.3","Cell RNA - TIME [nTPM]":"10.0","Cell RNA - U-138 MG [nTPM]":"60.7","Cell RNA - U-2 OS [nTPM]":"7.4","Cell RNA - U-2197 [nTPM]":"69.0","Cell RNA - U-251 MG [nTPM]":"6.8","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"8.4","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"5.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.3","Brain RNA - basal ganglia [nTPM]":"3.5","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"3.1","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"0.3","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"2.5","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"5.2","Brain RNA - white matter [nTPM]":"6.2","Single Cell Type RNA - Adipocytes [nTPM]":"42.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"38.3","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"83.6","Single Cell Type RNA - Bipolar cells [nTPM]":"2.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"16.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"69.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.8","Single Cell Type RNA - Endothelial cells [nTPM]":"43.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"46.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"34.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"43.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.2","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"61.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.5","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"3.2","Single Cell Type RNA - Langerhans cells [nTPM]":"5.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"14.0","Single Cell Type RNA - Macrophages [nTPM]":"1.9","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.7","Single Cell Type RNA - Paneth cells [nTPM]":"3.0","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"1.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"4.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.7","Single Cell Type RNA - Urothelial cells [nTPM]":"3.2"},{"Gene":"KRT5","Gene synonym":["EBS2","KRT5A"],"Ensembl":"ENSG00000186081","Gene description":"Keratin 5","Uniprot":["P13647"],"Chromosome":"12","Position":"52514575-52520530","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Epidermolysis bullosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"esophagus":"5865.0","skin 1":"5885.4","vagina":"2150.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"5870.1","Basal prostatic cells":"1037.6","Basal squamous epithelial cells":"1571.3","Squamous epithelial cells":"4370.9","Suprabasal keratinocytes":"2020.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"cervical cancer":"1863.2","head and neck cancer":"3340.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"326","RNA blood cell specific nTPM":{"plasmacytoid DC":"32.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"326","RNA blood lineage specific nTPM":{"dendritic cells":"32.6"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"HaCaT":"3368.0","HBEC3-KT":"5990.5","hTCEpi":"13326.8"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"8","RNA pig brain regional specific nTPM":{"spinal cord":"36.4"},"Antibody":["CAB000027","CAB000129","HPA059479"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Intermediate filaments"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3600000000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 61: Squamous epithelial cells - Keratinization","Subcellular main location":["Intermediate filaments"],"Subcellular additional location":null,"Antibody RRID":{"CAB000027":"AB_2281083","CAB000129":null,"HPA059479":"AB_2684034"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.27e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.01e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-3"},"Tissue RNA - adipose tissue [nTPM]":"10.0","Tissue RNA - adrenal gland [nTPM]":"1.7","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"1.8","Tissue RNA - basal ganglia [nTPM]":"0.8","Tissue RNA - bone marrow [nTPM]":"4.6","Tissue RNA - breast [nTPM]":"252.5","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"826.2","Tissue RNA - choroid plexus [nTPM]":"58.9","Tissue RNA - colon [nTPM]":"1.9","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"2.0","Tissue RNA - epididymis [nTPM]":"97.2","Tissue RNA - esophagus [nTPM]":"5865.0","Tissue RNA - fallopian tube [nTPM]":"12.5","Tissue RNA - gallbladder [nTPM]":"2.0","Tissue RNA - heart muscle [nTPM]":"3.8","Tissue RNA - hippocampal formation [nTPM]":"1.7","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"1.3","Tissue RNA - liver [nTPM]":"3.5","Tissue RNA - lung [nTPM]":"6.4","Tissue RNA - lymph node [nTPM]":"3.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"2.2","Tissue RNA - pancreas [nTPM]":"4.7","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"8.2","Tissue RNA - placenta [nTPM]":"2.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"125.8","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"880.3","Tissue RNA - seminal vesicle [nTPM]":"100.0","Tissue RNA - skeletal muscle [nTPM]":"9.9","Tissue RNA - skin 1 [nTPM]":"5885.4","Tissue RNA - small intestine [nTPM]":"1.8","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"1.7","Tissue RNA - stomach 1 [nTPM]":"5.0","Tissue RNA - testis [nTPM]":"2.1","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"527.1","Tissue RNA - thyroid gland [nTPM]":"3.0","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"648.6","Tissue RNA - urinary bladder [nTPM]":"93.2","Tissue RNA - vagina [nTPM]":"2150.9","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"50.6","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"2.3","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.8","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.0","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"2.4","Cell RNA - EFO-21 [nTPM]":"0.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"3368.0","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"5990.5","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.6","Cell RNA - HL-60 [nTPM]":"1.4","Cell RNA - HMC-1 [nTPM]":"2.8","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"13326.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"1049.7","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.8","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"1.8","Cell RNA - Karpas-707 [nTPM]":"4.0","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"1.0","Cell RNA - RPMI-8226 [nTPM]":"1.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.8","Cell RNA - RT4 [nTPM]":"0.9","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"1.2","Cell RNA - SK-BR-3 [nTPM]":"0.8","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"1.5","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"10.1","Cell RNA - U-266\/84 [nTPM]":"1.0","Cell RNA - U-698 [nTPM]":"0.9","Cell RNA - U-87 MG [nTPM]":"4.0","Cell RNA - U-937 [nTPM]":"1.4","Cell RNA - WM-115 [nTPM]":"0.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"32.6","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.8","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"1.7","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"1.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5870.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1037.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"627.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1571.3","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"43.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"226.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"180.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"39.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"31.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.2","Single Cell Type RNA - Endothelial cells [nTPM]":"26.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"29.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"44.7","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"273.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"7.3","Single Cell Type RNA - Melanocytes [nTPM]":"286.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"22.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"789.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"34.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"33.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4370.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2020.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"17.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"459.8"},{"Gene":"KRT71","Gene synonym":["K6IRS1","KRT6IRS","KRT6IRS1"],"Ensembl":"ENSG00000139648","Gene description":"Keratin 71","Uniprot":["Q3SY84"],"Chromosome":"12","Position":"52543909-52553145","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Hypotrichosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"23","RNA tissue specific nTPM":{"skin 1":"100.0"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"0.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"15","RNA cell line specific nTPM":{"CACO-2":"6.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049404"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049404":"AB_2680748"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.3","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"4.4","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"100.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.7","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"6.3","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"KRT74","Gene synonym":["K6IRS4","KRT5C","KRT6IRS4"],"Ensembl":"ENSG00000170484","Gene description":"Keratin 74","Uniprot":["Q7RTS7"],"Chromosome":"12","Position":"52565782-52573843","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Ectodermal dysplasia","Hypotrichosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"epididymis":"5.6","skin 1":"16.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Late spermatids":"5.2"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040655","HPA048596"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Intermediate filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"130000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Intermediate filaments"],"Subcellular additional location":["Nucleoli","Cytosol"],"Antibody RRID":{"HPA040655":null,"HPA048596":"AB_2680457"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-3"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.8","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"5.6","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"16.3","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"5.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"KRT75","Gene synonym":["K6HF"],"Ensembl":"ENSG00000170454","Gene description":"Keratin 75","Uniprot":["O95678"],"Chromosome":"12","Position":"52424070-52434371","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"skin 1":"27.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nTPM":{"Ductal cells":"20.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"head and neck cancer":"36.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"PC-3":"38.5","U-2 OS":"50.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019367","HPA076201"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1500000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 9: U-2 OS - Unknown function","Single cell expression cluster":"Cluster 1: Pancreatic cells - Digestion","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA019367":"AB_1852239","HPA076201":"AB_2686786"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.7","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"27.5","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"1.8","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.7","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"7.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"38.5","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"50.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"3.4","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"20.4","Single Cell Type RNA - Early spermatids [nTPM]":"2.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"LBR","Gene synonym":["DHCR14B","TDRD18"],"Ensembl":"ENSG00000143815","Gene description":"Lamin B receptor","Uniprot":["Q14739"],"Chromosome":"1","Position":"225401502-225428925","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cholesterol biosynthesis","Cholesterol metabolism","Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis","Steroid metabolism","Sterol biosynthesis","Sterol metabolism"],"Molecular function":["DNA-binding","Oxidoreductase","Receptor"],"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"248.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA062236"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA062236":"AB_2684721"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.30e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.45e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Tissue RNA - adipose tissue [nTPM]":"28.6","Tissue RNA - adrenal gland [nTPM]":"9.1","Tissue RNA - amygdala [nTPM]":"8.8","Tissue RNA - appendix [nTPM]":"53.2","Tissue RNA - basal ganglia [nTPM]":"9.7","Tissue RNA - bone marrow [nTPM]":"95.7","Tissue RNA - breast [nTPM]":"17.1","Tissue RNA - cerebellum [nTPM]":"9.3","Tissue RNA - cerebral cortex [nTPM]":"11.9","Tissue RNA - cervix [nTPM]":"27.3","Tissue RNA - choroid plexus [nTPM]":"9.2","Tissue RNA - colon [nTPM]":"61.4","Tissue RNA - duodenum [nTPM]":"40.7","Tissue RNA - endometrium 1 [nTPM]":"47.0","Tissue RNA - epididymis [nTPM]":"44.4","Tissue RNA - esophagus [nTPM]":"29.7","Tissue RNA - fallopian tube [nTPM]":"31.8","Tissue RNA - gallbladder [nTPM]":"21.7","Tissue RNA - heart muscle [nTPM]":"10.0","Tissue RNA - hippocampal formation [nTPM]":"8.5","Tissue RNA - hypothalamus [nTPM]":"10.1","Tissue RNA - kidney [nTPM]":"19.4","Tissue RNA - liver [nTPM]":"47.3","Tissue RNA - lung [nTPM]":"19.2","Tissue RNA - lymph node [nTPM]":"81.6","Tissue RNA - medulla oblongata [nTPM]":"12.0","Tissue RNA - midbrain [nTPM]":"9.8","Tissue RNA - ovary [nTPM]":"19.4","Tissue RNA - pancreas [nTPM]":"16.9","Tissue RNA - parathyroid gland [nTPM]":"5.6","Tissue RNA - pituitary gland [nTPM]":"6.5","Tissue RNA - placenta [nTPM]":"27.6","Tissue RNA - pons [nTPM]":"11.2","Tissue RNA - prostate [nTPM]":"23.8","Tissue RNA - rectum [nTPM]":"46.2","Tissue RNA - retina [nTPM]":"5.3","Tissue RNA - salivary gland [nTPM]":"11.1","Tissue RNA - seminal vesicle [nTPM]":"36.7","Tissue RNA - skeletal muscle [nTPM]":"9.8","Tissue RNA - skin 1 [nTPM]":"13.8","Tissue RNA - small intestine [nTPM]":"39.9","Tissue RNA - smooth muscle [nTPM]":"41.4","Tissue RNA - spinal cord [nTPM]":"10.2","Tissue RNA - spleen [nTPM]":"41.5","Tissue RNA - stomach 1 [nTPM]":"28.2","Tissue RNA - testis [nTPM]":"20.5","Tissue RNA - thalamus [nTPM]":"9.5","Tissue RNA - thymus [nTPM]":"105.5","Tissue RNA - thyroid gland [nTPM]":"11.8","Tissue RNA - tongue [nTPM]":"12.8","Tissue RNA - tonsil [nTPM]":"70.7","Tissue RNA - urinary bladder [nTPM]":"32.3","Tissue RNA - vagina [nTPM]":"23.0","Tissue RNA - white matter [nTPM]":"13.1","Cell RNA - A-431 [nTPM]":"122.2","Cell RNA - A549 [nTPM]":"42.0","Cell RNA - AF22 [nTPM]":"154.9","Cell RNA - AN3-CA [nTPM]":"69.3","Cell RNA - ASC diff [nTPM]":"64.8","Cell RNA - ASC TERT1 [nTPM]":"39.7","Cell RNA - BEWO [nTPM]":"77.3","Cell RNA - BJ [nTPM]":"31.2","Cell RNA - BJ hTERT+ [nTPM]":"39.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"65.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"69.0","Cell RNA - CACO-2 [nTPM]":"87.2","Cell RNA - CAPAN-2 [nTPM]":"207.2","Cell RNA - Daudi [nTPM]":"248.4","Cell RNA - EFO-21 [nTPM]":"66.6","Cell RNA - fHDF\/TERT166 [nTPM]":"32.8","Cell RNA - GAMG [nTPM]":"38.6","Cell RNA - HaCaT [nTPM]":"88.8","Cell RNA - HAP1 [nTPM]":"114.2","Cell RNA - HBEC3-KT [nTPM]":"32.9","Cell RNA - HBF TERT88 [nTPM]":"98.5","Cell RNA - HDLM-2 [nTPM]":"142.2","Cell RNA - HEK 293 [nTPM]":"107.1","Cell RNA - HEL [nTPM]":"61.4","Cell RNA - HeLa [nTPM]":"40.4","Cell RNA - Hep G2 [nTPM]":"81.5","Cell RNA - HHSteC [nTPM]":"39.9","Cell RNA - HL-60 [nTPM]":"274.7","Cell RNA - HMC-1 [nTPM]":"105.5","Cell RNA - HSkMC [nTPM]":"34.3","Cell RNA - hTCEpi [nTPM]":"21.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"58.9","Cell RNA - hTERT-HME1 [nTPM]":"52.0","Cell RNA - hTERT-RPE1 [nTPM]":"33.1","Cell RNA - HUVEC TERT2 [nTPM]":"82.9","Cell RNA - JURKAT [nTPM]":"117.4","Cell RNA - K-562 [nTPM]":"189.6","Cell RNA - Karpas-707 [nTPM]":"164.6","Cell RNA - LHCN-M2 [nTPM]":"44.4","Cell RNA - MCF7 [nTPM]":"16.3","Cell RNA - MOLT-4 [nTPM]":"254.9","Cell RNA - NB-4 [nTPM]":"156.6","Cell RNA - NTERA-2 [nTPM]":"140.6","Cell RNA - OE19 [nTPM]":"121.8","Cell RNA - PC-3 [nTPM]":"14.2","Cell RNA - REH [nTPM]":"164.9","Cell RNA - RH-30 [nTPM]":"141.4","Cell RNA - RPMI-8226 [nTPM]":"234.0","Cell RNA - RPTEC TERT1 [nTPM]":"75.6","Cell RNA - RT4 [nTPM]":"52.7","Cell RNA - SCLC-21H [nTPM]":"40.6","Cell RNA - SH-SY5Y [nTPM]":"53.4","Cell RNA - SiHa [nTPM]":"52.7","Cell RNA - SK-BR-3 [nTPM]":"39.6","Cell RNA - SK-MEL-30 [nTPM]":"26.6","Cell RNA - SuSa [nTPM]":"68.2","Cell RNA - T-47d [nTPM]":"53.3","Cell RNA - THP-1 [nTPM]":"181.0","Cell RNA - TIME [nTPM]":"50.5","Cell RNA - U-138 MG [nTPM]":"17.6","Cell RNA - U-2 OS [nTPM]":"91.7","Cell RNA - U-2197 [nTPM]":"49.3","Cell RNA - U-251 MG [nTPM]":"115.9","Cell RNA - U-266\/70 [nTPM]":"56.6","Cell RNA - U-266\/84 [nTPM]":"83.0","Cell RNA - U-698 [nTPM]":"274.5","Cell RNA - U-87 MG [nTPM]":"24.3","Cell RNA - U-937 [nTPM]":"120.5","Cell RNA - WM-115 [nTPM]":"61.2","Blood RNA - basophil [nTPM]":"83.6","Blood RNA - classical monocyte [nTPM]":"44.3","Blood RNA - eosinophil [nTPM]":"67.3","Blood RNA - gdT-cell [nTPM]":"43.6","Blood RNA - intermediate monocyte [nTPM]":"31.6","Blood RNA - MAIT T-cell [nTPM]":"50.9","Blood RNA - memory B-cell [nTPM]":"39.0","Blood RNA - memory CD4 T-cell [nTPM]":"43.5","Blood RNA - memory CD8 T-cell [nTPM]":"48.8","Blood RNA - myeloid DC [nTPM]":"38.4","Blood RNA - naive B-cell [nTPM]":"39.5","Blood RNA - naive CD4 T-cell [nTPM]":"42.4","Blood RNA - naive CD8 T-cell [nTPM]":"52.9","Blood RNA - neutrophil [nTPM]":"211.4","Blood RNA - NK-cell [nTPM]":"41.3","Blood RNA - non-classical monocyte [nTPM]":"25.2","Blood RNA - plasmacytoid DC [nTPM]":"21.5","Blood RNA - T-reg [nTPM]":"61.9","Blood RNA - total PBMC [nTPM]":"69.8","Brain RNA - amygdala [nTPM]":"8.8","Brain RNA - basal ganglia [nTPM]":"9.7","Brain RNA - cerebellum [nTPM]":"9.3","Brain RNA - cerebral cortex [nTPM]":"11.9","Brain RNA - hippocampal formation [nTPM]":"8.5","Brain RNA - hypothalamus [nTPM]":"10.1","Brain RNA - medulla oblongata [nTPM]":"12.0","Brain RNA - midbrain [nTPM]":"9.8","Brain RNA - pons [nTPM]":"11.2","Brain RNA - spinal cord [nTPM]":"10.2","Brain RNA - thalamus [nTPM]":"9.5","Brain RNA - white matter [nTPM]":"13.1","Single Cell Type RNA - Adipocytes [nTPM]":"98.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"36.4","Single Cell Type RNA - Astrocytes [nTPM]":"13.4","Single Cell Type RNA - B-cells [nTPM]":"86.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"27.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"33.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.6","Single Cell Type RNA - Bipolar cells [nTPM]":"4.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"48.6","Single Cell Type RNA - Club cells [nTPM]":"34.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"40.5","Single Cell Type RNA - dendritic cells [nTPM]":"98.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"33.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"23.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"31.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"31.0","Single Cell Type RNA - Endothelial cells [nTPM]":"53.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"27.0","Single Cell Type RNA - Erythroid cells [nTPM]":"248.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"23.9","Single Cell Type RNA - Fibroblasts [nTPM]":"29.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"29.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"53.9","Single Cell Type RNA - granulocytes [nTPM]":"10.1","Single Cell Type RNA - Granulosa cells [nTPM]":"24.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"48.5","Single Cell Type RNA - Hepatocytes [nTPM]":"73.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"44.4","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"43.0","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"88.5","Single Cell Type RNA - Langerhans cells [nTPM]":"18.1","Single Cell Type RNA - Late spermatids [nTPM]":"3.4","Single Cell Type RNA - Leydig cells [nTPM]":"33.8","Single Cell Type RNA - Macrophages [nTPM]":"71.7","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"56.0","Single Cell Type RNA - Muller glia cells [nTPM]":"11.6","Single Cell Type RNA - NK-cells [nTPM]":"82.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"37.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"34.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.6","Single Cell Type RNA - Paneth cells [nTPM]":"24.6","Single Cell Type RNA - Peritubular cells [nTPM]":"32.4","Single Cell Type RNA - Plasma cells [nTPM]":"74.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"32.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"26.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"26.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"46.6","Single Cell Type RNA - Spermatocytes [nTPM]":"21.0","Single Cell Type RNA - Spermatogonia [nTPM]":"26.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"68.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"35.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.1","Single Cell Type RNA - T-cells [nTPM]":"81.3","Single Cell Type RNA - Theca cells [nTPM]":"13.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"73.8","Single Cell Type RNA - Urothelial cells [nTPM]":"36.7"},{"Gene":"LIPH","Gene synonym":["LPDLR","mPA-PLA1","mPA-PLA1alpha","PLA1B"],"Ensembl":"ENSG00000163898","Gene description":"Lipase H","Uniprot":["Q8WWY8"],"Chromosome":"3","Position":"185506262-185552588","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Heparin-binding","Hydrolase"],"Disease involvement":["Disease variant","Hypotrichosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"37.7","stomach 1":"48.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"144.2","Club cells":"135.5","Distal enterocytes":"312.3","Gastric mucus-secreting cells":"236.5","Intestinal goblet cells":"139.8","Proximal enterocytes":"226.1","Urothelial cells":"158.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"74.1","OE19":"17.2","RPTEC TERT1":"36.7","T-47d":"17.6","U-266\/84":"18.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049079"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049079":"AB_2680623"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.40e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.59e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.20e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.21e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"2.8","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"3.8","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"2.8","Tissue RNA - choroid plexus [nTPM]":"6.9","Tissue RNA - colon [nTPM]":"36.3","Tissue RNA - duodenum [nTPM]":"11.1","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"7.1","Tissue RNA - esophagus [nTPM]":"14.7","Tissue RNA - fallopian tube [nTPM]":"1.1","Tissue RNA - gallbladder [nTPM]":"12.3","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"0.4","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"7.8","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"18.3","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"5.5","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"6.8","Tissue RNA - rectum [nTPM]":"37.7","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"13.2","Tissue RNA - seminal vesicle [nTPM]":"2.0","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"7.4","Tissue RNA - small intestine [nTPM]":"11.8","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"48.2","Tissue RNA - testis [nTPM]":"2.7","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"3.0","Tissue RNA - urinary bladder [nTPM]":"12.2","Tissue RNA - vagina [nTPM]":"4.3","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"10.3","Cell RNA - A549 [nTPM]":"13.5","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"2.9","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"1.3","Cell RNA - CAPAN-2 [nTPM]":"74.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"7.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"2.9","Cell RNA - HaCaT [nTPM]":"3.6","Cell RNA - HAP1 [nTPM]":"5.6","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"1.6","Cell RNA - HEL [nTPM]":"1.8","Cell RNA - HeLa [nTPM]":"1.8","Cell RNA - Hep G2 [nTPM]":"1.4","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"5.4","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.3","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"17.2","Cell RNA - PC-3 [nTPM]":"1.1","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.0","Cell RNA - RPTEC TERT1 [nTPM]":"36.7","Cell RNA - RT4 [nTPM]":"9.2","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"1.1","Cell RNA - SK-BR-3 [nTPM]":"12.2","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"17.6","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"1.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"1.2","Cell RNA - U-266\/84 [nTPM]":"18.9","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.4","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"144.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"38.5","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"76.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"55.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"94.4","Single Cell Type RNA - Club cells [nTPM]":"135.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"68.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"1.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"312.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"57.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"1.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"236.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.7","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"36.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"139.8","Single Cell Type RNA - Ionocytes [nTPM]":"38.7","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.4","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"60.4","Single Cell Type RNA - Paneth cells [nTPM]":"102.7","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"72.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"226.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"105.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.5","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"12.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"102.1","Single Cell Type RNA - Urothelial cells [nTPM]":"158.0"},{"Gene":"LPAR6","Gene synonym":["P2RY5","P2Y5"],"Ensembl":"ENSG00000139679","Gene description":"Lysophosphatidic acid receptor 6","Uniprot":["P43657"],"Chromosome":"13","Position":"48389567-48444704","Protein class":["Disease related genes","G-protein coupled receptors","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","Hypotrichosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"266.1","Basal squamous epithelial cells":"327.2","Early spermatids":"334.0","Langerhans cells":"703.7","Late spermatids":"321.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"21.6","HUVEC TERT2":"35.3","MOLT-4":"20.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028934"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA028934":"AB_2672833"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.30e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.22e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.60e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Tissue RNA - adipose tissue [nTPM]":"41.0","Tissue RNA - adrenal gland [nTPM]":"26.5","Tissue RNA - amygdala [nTPM]":"14.5","Tissue RNA - appendix [nTPM]":"26.8","Tissue RNA - basal ganglia [nTPM]":"14.7","Tissue RNA - bone marrow [nTPM]":"6.1","Tissue RNA - breast [nTPM]":"43.0","Tissue RNA - cerebellum [nTPM]":"15.2","Tissue RNA - cerebral cortex [nTPM]":"27.1","Tissue RNA - cervix [nTPM]":"41.9","Tissue RNA - choroid plexus [nTPM]":"18.3","Tissue RNA - colon [nTPM]":"22.1","Tissue RNA - duodenum [nTPM]":"15.0","Tissue RNA - endometrium 1 [nTPM]":"28.7","Tissue RNA - epididymis [nTPM]":"39.5","Tissue RNA - esophagus [nTPM]":"81.8","Tissue RNA - fallopian tube [nTPM]":"22.2","Tissue RNA - gallbladder [nTPM]":"35.5","Tissue RNA - heart muscle [nTPM]":"24.9","Tissue RNA - hippocampal formation [nTPM]":"14.0","Tissue RNA - hypothalamus [nTPM]":"15.8","Tissue RNA - kidney [nTPM]":"26.2","Tissue RNA - liver [nTPM]":"23.2","Tissue RNA - lung [nTPM]":"34.6","Tissue RNA - lymph node [nTPM]":"45.6","Tissue RNA - medulla oblongata [nTPM]":"19.0","Tissue RNA - midbrain [nTPM]":"16.4","Tissue RNA - ovary [nTPM]":"14.9","Tissue RNA - pancreas [nTPM]":"8.7","Tissue RNA - parathyroid gland [nTPM]":"9.7","Tissue RNA - pituitary gland [nTPM]":"15.9","Tissue RNA - placenta [nTPM]":"77.7","Tissue RNA - pons [nTPM]":"18.0","Tissue RNA - prostate [nTPM]":"60.7","Tissue RNA - rectum [nTPM]":"27.6","Tissue RNA - retina [nTPM]":"5.8","Tissue RNA - salivary gland [nTPM]":"59.7","Tissue RNA - seminal vesicle [nTPM]":"32.2","Tissue RNA - skeletal muscle [nTPM]":"9.0","Tissue RNA - skin 1 [nTPM]":"33.9","Tissue RNA - small intestine [nTPM]":"21.7","Tissue RNA - smooth muscle [nTPM]":"27.1","Tissue RNA - spinal cord [nTPM]":"18.2","Tissue RNA - spleen [nTPM]":"40.2","Tissue RNA - stomach 1 [nTPM]":"21.6","Tissue RNA - testis [nTPM]":"8.1","Tissue RNA - thalamus [nTPM]":"16.7","Tissue RNA - thymus [nTPM]":"36.4","Tissue RNA - thyroid gland [nTPM]":"24.3","Tissue RNA - tongue [nTPM]":"20.8","Tissue RNA - tonsil [nTPM]":"41.1","Tissue RNA - urinary bladder [nTPM]":"40.8","Tissue RNA - vagina [nTPM]":"75.1","Tissue RNA - white matter [nTPM]":"21.0","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"2.1","Cell RNA - AF22 [nTPM]":"21.6","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"7.0","Cell RNA - ASC TERT1 [nTPM]":"8.6","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"4.5","Cell RNA - BJ hTERT+ [nTPM]":"12.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.5","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"6.4","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"4.9","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"12.7","Cell RNA - HAP1 [nTPM]":"0.6","Cell RNA - HBEC3-KT [nTPM]":"7.2","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"4.3","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"15.9","Cell RNA - HHSteC [nTPM]":"4.6","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"11.5","Cell RNA - hTCEpi [nTPM]":"12.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.5","Cell RNA - hTERT-HME1 [nTPM]":"7.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"35.3","Cell RNA - JURKAT [nTPM]":"7.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"4.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"20.0","Cell RNA - NB-4 [nTPM]":"6.3","Cell RNA - NTERA-2 [nTPM]":"8.6","Cell RNA - OE19 [nTPM]":"0.4","Cell RNA - PC-3 [nTPM]":"5.9","Cell RNA - REH [nTPM]":"16.9","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"5.9","Cell RNA - RT4 [nTPM]":"13.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"4.5","Cell RNA - SuSa [nTPM]":"13.2","Cell RNA - T-47d [nTPM]":"2.2","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"9.1","Cell RNA - U-138 MG [nTPM]":"2.4","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"1.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.7","Cell RNA - U-937 [nTPM]":"1.1","Cell RNA - WM-115 [nTPM]":"7.8","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"71.9","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"24.6","Blood RNA - intermediate monocyte [nTPM]":"112.0","Blood RNA - MAIT T-cell [nTPM]":"13.6","Blood RNA - memory B-cell [nTPM]":"1.2","Blood RNA - memory CD4 T-cell [nTPM]":"70.0","Blood RNA - memory CD8 T-cell [nTPM]":"29.4","Blood RNA - myeloid DC [nTPM]":"26.0","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"49.3","Blood RNA - naive CD8 T-cell [nTPM]":"15.6","Blood RNA - neutrophil [nTPM]":"5.9","Blood RNA - NK-cell [nTPM]":"6.9","Blood RNA - non-classical monocyte [nTPM]":"103.6","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"83.9","Blood RNA - total PBMC [nTPM]":"58.2","Brain RNA - amygdala [nTPM]":"14.5","Brain RNA - basal ganglia [nTPM]":"14.7","Brain RNA - cerebellum [nTPM]":"15.2","Brain RNA - cerebral cortex [nTPM]":"27.1","Brain RNA - hippocampal formation [nTPM]":"14.0","Brain RNA - hypothalamus [nTPM]":"15.8","Brain RNA - medulla oblongata [nTPM]":"19.0","Brain RNA - midbrain [nTPM]":"16.4","Brain RNA - pons [nTPM]":"18.0","Brain RNA - spinal cord [nTPM]":"18.2","Brain RNA - thalamus [nTPM]":"16.7","Brain RNA - white matter [nTPM]":"21.0","Single Cell Type RNA - Adipocytes [nTPM]":"266.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.7","Single Cell Type RNA - Astrocytes [nTPM]":"4.9","Single Cell Type RNA - B-cells [nTPM]":"5.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"120.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"196.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"155.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"327.2","Single Cell Type RNA - Bipolar cells [nTPM]":"1.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"30.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"76.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - dendritic cells [nTPM]":"22.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"10.4","Single Cell Type RNA - Early spermatids [nTPM]":"334.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.7","Single Cell Type RNA - Endothelial cells [nTPM]":"140.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.4","Single Cell Type RNA - Erythroid cells [nTPM]":"8.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"23.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.8","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"5.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"136.0","Single Cell Type RNA - Hepatocytes [nTPM]":"2.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"82.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.9","Single Cell Type RNA - Ionocytes [nTPM]":"42.7","Single Cell Type RNA - Kupffer cells [nTPM]":"74.0","Single Cell Type RNA - Langerhans cells [nTPM]":"703.7","Single Cell Type RNA - Late spermatids [nTPM]":"321.7","Single Cell Type RNA - Leydig cells [nTPM]":"22.7","Single Cell Type RNA - Macrophages [nTPM]":"111.9","Single Cell Type RNA - Melanocytes [nTPM]":"49.8","Single Cell Type RNA - Microglial cells [nTPM]":"177.1","Single Cell Type RNA - monocytes [nTPM]":"76.4","Single Cell Type RNA - Muller glia cells [nTPM]":"11.3","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.7","Single Cell Type RNA - Paneth cells [nTPM]":"4.1","Single Cell Type RNA - Peritubular cells [nTPM]":"15.8","Single Cell Type RNA - Plasma cells [nTPM]":"6.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"107.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"25.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"49.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.3","Single Cell Type RNA - Spermatocytes [nTPM]":"2.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"182.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"142.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"52.3","Single Cell Type RNA - Theca cells [nTPM]":"14.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.6","Single Cell Type RNA - Urothelial cells [nTPM]":"143.5"},{"Gene":"LSS","Gene synonym":["OSC"],"Ensembl":"ENSG00000160285","Gene description":"Lanosterol synthase","Uniprot":["P48449"],"Chromosome":"21","Position":"46188141-46228824","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Steroid biosynthesis"],"Molecular function":["Isomerase"],"Disease involvement":["Cataract","Disease variant","Hypotrichosis","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"132.0","Oligodendrocytes":"158.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"GAMG":"234.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032060","HPA032062","CAB034116"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 15: Hepatocytes - Hemostasis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB034116":"AB_2138611","HPA032060":"AB_10671085","HPA032062":"AB_2674134"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.80e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.07e-4"},"Tissue RNA - adipose tissue [nTPM]":"29.3","Tissue RNA - adrenal gland [nTPM]":"38.9","Tissue RNA - amygdala [nTPM]":"20.0","Tissue RNA - appendix [nTPM]":"10.8","Tissue RNA - basal ganglia [nTPM]":"30.8","Tissue RNA - bone marrow [nTPM]":"5.7","Tissue RNA - breast [nTPM]":"22.3","Tissue RNA - cerebellum [nTPM]":"38.9","Tissue RNA - cerebral cortex [nTPM]":"33.5","Tissue RNA - cervix [nTPM]":"20.8","Tissue RNA - choroid plexus [nTPM]":"7.1","Tissue RNA - colon [nTPM]":"22.9","Tissue RNA - duodenum [nTPM]":"28.5","Tissue RNA - endometrium 1 [nTPM]":"26.6","Tissue RNA - epididymis [nTPM]":"12.1","Tissue RNA - esophagus [nTPM]":"39.7","Tissue RNA - fallopian tube [nTPM]":"18.0","Tissue RNA - gallbladder [nTPM]":"9.0","Tissue RNA - heart muscle [nTPM]":"25.1","Tissue RNA - hippocampal formation [nTPM]":"15.7","Tissue RNA - hypothalamus [nTPM]":"26.2","Tissue RNA - kidney [nTPM]":"10.7","Tissue RNA - liver [nTPM]":"54.8","Tissue RNA - lung [nTPM]":"24.1","Tissue RNA - lymph node [nTPM]":"9.4","Tissue RNA - medulla oblongata [nTPM]":"62.3","Tissue RNA - midbrain [nTPM]":"40.7","Tissue RNA - ovary [nTPM]":"30.3","Tissue RNA - pancreas [nTPM]":"19.4","Tissue RNA - parathyroid gland [nTPM]":"12.2","Tissue RNA - pituitary gland [nTPM]":"25.9","Tissue RNA - placenta [nTPM]":"8.0","Tissue RNA - pons [nTPM]":"65.7","Tissue RNA - prostate [nTPM]":"24.0","Tissue RNA - rectum [nTPM]":"10.7","Tissue RNA - retina [nTPM]":"6.8","Tissue RNA - salivary gland [nTPM]":"16.1","Tissue RNA - seminal vesicle [nTPM]":"12.4","Tissue RNA - skeletal muscle [nTPM]":"29.0","Tissue RNA - skin 1 [nTPM]":"27.6","Tissue RNA - small intestine [nTPM]":"17.4","Tissue RNA - smooth muscle [nTPM]":"12.2","Tissue RNA - spinal cord [nTPM]":"28.4","Tissue RNA - spleen [nTPM]":"7.6","Tissue RNA - stomach 1 [nTPM]":"23.3","Tissue RNA - testis [nTPM]":"17.5","Tissue RNA - thalamus [nTPM]":"40.4","Tissue RNA - thymus [nTPM]":"12.3","Tissue RNA - thyroid gland [nTPM]":"10.2","Tissue RNA - tongue [nTPM]":"19.5","Tissue RNA - tonsil [nTPM]":"8.0","Tissue RNA - urinary bladder [nTPM]":"20.2","Tissue RNA - vagina [nTPM]":"19.6","Tissue RNA - white matter [nTPM]":"58.7","Cell RNA - A-431 [nTPM]":"70.4","Cell RNA - A549 [nTPM]":"22.2","Cell RNA - AF22 [nTPM]":"70.9","Cell RNA - AN3-CA [nTPM]":"30.6","Cell RNA - ASC diff [nTPM]":"94.1","Cell RNA - ASC TERT1 [nTPM]":"90.6","Cell RNA - BEWO [nTPM]":"20.3","Cell RNA - BJ [nTPM]":"26.8","Cell RNA - BJ hTERT+ [nTPM]":"186.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"32.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"62.7","Cell RNA - CACO-2 [nTPM]":"73.9","Cell RNA - CAPAN-2 [nTPM]":"54.4","Cell RNA - Daudi [nTPM]":"15.4","Cell RNA - EFO-21 [nTPM]":"22.3","Cell RNA - fHDF\/TERT166 [nTPM]":"51.7","Cell RNA - GAMG [nTPM]":"234.6","Cell RNA - HaCaT [nTPM]":"32.7","Cell RNA - HAP1 [nTPM]":"63.2","Cell RNA - HBEC3-KT [nTPM]":"110.9","Cell RNA - HBF TERT88 [nTPM]":"12.9","Cell RNA - HDLM-2 [nTPM]":"14.9","Cell RNA - HEK 293 [nTPM]":"34.5","Cell RNA - HEL [nTPM]":"37.7","Cell RNA - HeLa [nTPM]":"38.6","Cell RNA - Hep G2 [nTPM]":"48.3","Cell RNA - HHSteC [nTPM]":"85.5","Cell RNA - HL-60 [nTPM]":"13.7","Cell RNA - HMC-1 [nTPM]":"25.1","Cell RNA - HSkMC [nTPM]":"89.0","Cell RNA - hTCEpi [nTPM]":"41.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"59.7","Cell RNA - hTERT-HME1 [nTPM]":"25.6","Cell RNA - hTERT-RPE1 [nTPM]":"22.2","Cell RNA - HUVEC TERT2 [nTPM]":"26.9","Cell RNA - JURKAT [nTPM]":"72.1","Cell RNA - K-562 [nTPM]":"37.4","Cell RNA - Karpas-707 [nTPM]":"87.3","Cell RNA - LHCN-M2 [nTPM]":"27.8","Cell RNA - MCF7 [nTPM]":"23.8","Cell RNA - MOLT-4 [nTPM]":"29.9","Cell RNA - NB-4 [nTPM]":"19.7","Cell RNA - NTERA-2 [nTPM]":"115.4","Cell RNA - OE19 [nTPM]":"11.3","Cell RNA - PC-3 [nTPM]":"20.1","Cell RNA - REH [nTPM]":"34.9","Cell RNA - RH-30 [nTPM]":"21.9","Cell RNA - RPMI-8226 [nTPM]":"92.2","Cell RNA - RPTEC TERT1 [nTPM]":"82.8","Cell RNA - RT4 [nTPM]":"38.1","Cell RNA - SCLC-21H [nTPM]":"41.4","Cell RNA - SH-SY5Y [nTPM]":"36.7","Cell RNA - SiHa [nTPM]":"31.4","Cell RNA - SK-BR-3 [nTPM]":"24.0","Cell RNA - SK-MEL-30 [nTPM]":"27.5","Cell RNA - SuSa [nTPM]":"30.6","Cell RNA - T-47d [nTPM]":"38.0","Cell RNA - THP-1 [nTPM]":"33.7","Cell RNA - TIME [nTPM]":"40.8","Cell RNA - U-138 MG [nTPM]":"37.9","Cell RNA - U-2 OS [nTPM]":"30.2","Cell RNA - U-2197 [nTPM]":"33.8","Cell RNA - U-251 MG [nTPM]":"21.1","Cell RNA - U-266\/70 [nTPM]":"31.8","Cell RNA - U-266\/84 [nTPM]":"29.5","Cell RNA - U-698 [nTPM]":"30.6","Cell RNA - U-87 MG [nTPM]":"39.7","Cell RNA - U-937 [nTPM]":"59.4","Cell RNA - WM-115 [nTPM]":"16.6","Blood RNA - basophil [nTPM]":"4.6","Blood RNA - classical monocyte [nTPM]":"2.1","Blood RNA - eosinophil [nTPM]":"2.2","Blood RNA - gdT-cell [nTPM]":"4.0","Blood RNA - intermediate monocyte [nTPM]":"1.8","Blood RNA - MAIT T-cell [nTPM]":"2.8","Blood RNA - memory B-cell [nTPM]":"3.1","Blood RNA - memory CD4 T-cell [nTPM]":"2.9","Blood RNA - memory CD8 T-cell [nTPM]":"4.9","Blood RNA - myeloid DC [nTPM]":"2.4","Blood RNA - naive B-cell [nTPM]":"1.5","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"3.6","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.7","Blood RNA - non-classical monocyte [nTPM]":"1.5","Blood RNA - plasmacytoid DC [nTPM]":"5.0","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"3.6","Brain RNA - amygdala [nTPM]":"20.0","Brain RNA - basal ganglia [nTPM]":"30.8","Brain RNA - cerebellum [nTPM]":"38.9","Brain RNA - cerebral cortex [nTPM]":"33.5","Brain RNA - hippocampal formation [nTPM]":"15.7","Brain RNA - hypothalamus [nTPM]":"26.2","Brain RNA - medulla oblongata [nTPM]":"62.3","Brain RNA - midbrain [nTPM]":"40.7","Brain RNA - pons [nTPM]":"65.7","Brain RNA - spinal cord [nTPM]":"28.4","Brain RNA - thalamus [nTPM]":"40.4","Brain RNA - white matter [nTPM]":"58.7","Single Cell Type RNA - Adipocytes [nTPM]":"13.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"36.8","Single Cell Type RNA - Astrocytes [nTPM]":"66.6","Single Cell Type RNA - B-cells [nTPM]":"7.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"37.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"16.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"18.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.7","Single Cell Type RNA - dendritic cells [nTPM]":"11.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"10.5","Single Cell Type RNA - Early spermatids [nTPM]":"6.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.4","Single Cell Type RNA - Endothelial cells [nTPM]":"10.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.7","Single Cell Type RNA - Erythroid cells [nTPM]":"16.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"21.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.7","Single Cell Type RNA - Fibroblasts [nTPM]":"19.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.6","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"20.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.4","Single Cell Type RNA - Hepatocytes [nTPM]":"132.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.7","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"24.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.6","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.5","Single Cell Type RNA - Langerhans cells [nTPM]":"13.7","Single Cell Type RNA - Late spermatids [nTPM]":"6.6","Single Cell Type RNA - Leydig cells [nTPM]":"21.1","Single Cell Type RNA - Macrophages [nTPM]":"4.9","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"12.0","Single Cell Type RNA - Muller glia cells [nTPM]":"7.5","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"22.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"158.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"14.0","Single Cell Type RNA - Paneth cells [nTPM]":"2.7","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"6.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.5","Single Cell Type RNA - Spermatocytes [nTPM]":"20.3","Single Cell Type RNA - Spermatogonia [nTPM]":"18.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"54.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.3","Single Cell Type RNA - T-cells [nTPM]":"7.9","Single Cell Type RNA - Theca cells [nTPM]":"18.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.9","Single Cell Type RNA - Urothelial cells [nTPM]":"4.6"},{"Gene":"LTBP4","Gene synonym":["FLJ46318","FLJ90018","LTBP-4","LTBP-4L"],"Ensembl":"ENSG00000090006","Gene description":"Latent transforming growth factor beta binding protein 4","Uniprot":["Q8N2S1"],"Chromosome":"19","Position":"40592883-40629818","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Growth factor binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"327.1","Leydig cells":"972.3","Peritubular cells":"624.4","Skeletal myocytes":"229.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"120.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015194"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9700000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB015194":"AB_2139064"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.36e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-2"},"Tissue RNA - adipose tissue [nTPM]":"138.5","Tissue RNA - adrenal gland [nTPM]":"48.5","Tissue RNA - amygdala [nTPM]":"11.3","Tissue RNA - appendix [nTPM]":"22.3","Tissue RNA - basal ganglia [nTPM]":"10.9","Tissue RNA - bone marrow [nTPM]":"8.3","Tissue RNA - breast [nTPM]":"98.8","Tissue RNA - cerebellum [nTPM]":"1.7","Tissue RNA - cerebral cortex [nTPM]":"13.3","Tissue RNA - cervix [nTPM]":"334.6","Tissue RNA - choroid plexus [nTPM]":"9.6","Tissue RNA - colon [nTPM]":"144.5","Tissue RNA - duodenum [nTPM]":"59.2","Tissue RNA - endometrium 1 [nTPM]":"309.6","Tissue RNA - epididymis [nTPM]":"44.7","Tissue RNA - esophagus [nTPM]":"100.6","Tissue RNA - fallopian tube [nTPM]":"246.8","Tissue RNA - gallbladder [nTPM]":"39.3","Tissue RNA - heart muscle [nTPM]":"401.9","Tissue RNA - hippocampal formation [nTPM]":"10.7","Tissue RNA - hypothalamus [nTPM]":"14.2","Tissue RNA - kidney [nTPM]":"64.7","Tissue RNA - liver [nTPM]":"37.4","Tissue RNA - lung [nTPM]":"242.5","Tissue RNA - lymph node [nTPM]":"24.8","Tissue RNA - medulla oblongata [nTPM]":"16.2","Tissue RNA - midbrain [nTPM]":"10.3","Tissue RNA - ovary [nTPM]":"315.2","Tissue RNA - pancreas [nTPM]":"37.2","Tissue RNA - parathyroid gland [nTPM]":"22.6","Tissue RNA - pituitary gland [nTPM]":"75.9","Tissue RNA - placenta [nTPM]":"38.3","Tissue RNA - pons [nTPM]":"16.4","Tissue RNA - prostate [nTPM]":"253.6","Tissue RNA - rectum [nTPM]":"38.2","Tissue RNA - retina [nTPM]":"3.7","Tissue RNA - salivary gland [nTPM]":"82.8","Tissue RNA - seminal vesicle [nTPM]":"126.3","Tissue RNA - skeletal muscle [nTPM]":"63.0","Tissue RNA - skin 1 [nTPM]":"73.0","Tissue RNA - small intestine [nTPM]":"135.4","Tissue RNA - smooth muscle [nTPM]":"74.4","Tissue RNA - spinal cord [nTPM]":"11.3","Tissue RNA - spleen [nTPM]":"80.5","Tissue RNA - stomach 1 [nTPM]":"125.3","Tissue RNA - testis [nTPM]":"78.5","Tissue RNA - thalamus [nTPM]":"14.2","Tissue RNA - thymus [nTPM]":"12.9","Tissue RNA - thyroid gland [nTPM]":"173.2","Tissue RNA - tongue [nTPM]":"156.7","Tissue RNA - tonsil [nTPM]":"14.0","Tissue RNA - urinary bladder [nTPM]":"188.6","Tissue RNA - vagina [nTPM]":"374.5","Tissue RNA - white matter [nTPM]":"15.3","Cell RNA - A-431 [nTPM]":"19.8","Cell RNA - A549 [nTPM]":"21.3","Cell RNA - AF22 [nTPM]":"41.7","Cell RNA - AN3-CA [nTPM]":"56.5","Cell RNA - ASC diff [nTPM]":"15.1","Cell RNA - ASC TERT1 [nTPM]":"16.0","Cell RNA - BEWO [nTPM]":"6.6","Cell RNA - BJ [nTPM]":"7.7","Cell RNA - BJ hTERT+ [nTPM]":"24.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.4","Cell RNA - CACO-2 [nTPM]":"6.4","Cell RNA - CAPAN-2 [nTPM]":"43.8","Cell RNA - Daudi [nTPM]":"22.4","Cell RNA - EFO-21 [nTPM]":"34.9","Cell RNA - fHDF\/TERT166 [nTPM]":"13.1","Cell RNA - GAMG [nTPM]":"12.4","Cell RNA - HaCaT [nTPM]":"26.3","Cell RNA - HAP1 [nTPM]":"10.6","Cell RNA - HBEC3-KT [nTPM]":"26.8","Cell RNA - HBF TERT88 [nTPM]":"2.6","Cell RNA - HDLM-2 [nTPM]":"61.0","Cell RNA - HEK 293 [nTPM]":"3.3","Cell RNA - HEL [nTPM]":"7.3","Cell RNA - HeLa [nTPM]":"53.7","Cell RNA - Hep G2 [nTPM]":"2.4","Cell RNA - HHSteC [nTPM]":"49.4","Cell RNA - HL-60 [nTPM]":"3.0","Cell RNA - HMC-1 [nTPM]":"23.1","Cell RNA - HSkMC [nTPM]":"19.9","Cell RNA - hTCEpi [nTPM]":"21.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.6","Cell RNA - hTERT-HME1 [nTPM]":"27.8","Cell RNA - hTERT-RPE1 [nTPM]":"41.0","Cell RNA - HUVEC TERT2 [nTPM]":"4.9","Cell RNA - JURKAT [nTPM]":"21.6","Cell RNA - K-562 [nTPM]":"46.7","Cell RNA - Karpas-707 [nTPM]":"120.3","Cell RNA - LHCN-M2 [nTPM]":"1.9","Cell RNA - MCF7 [nTPM]":"19.7","Cell RNA - MOLT-4 [nTPM]":"3.1","Cell RNA - NB-4 [nTPM]":"1.3","Cell RNA - NTERA-2 [nTPM]":"4.9","Cell RNA - OE19 [nTPM]":"56.1","Cell RNA - PC-3 [nTPM]":"24.9","Cell RNA - REH [nTPM]":"51.9","Cell RNA - RH-30 [nTPM]":"1.1","Cell RNA - RPMI-8226 [nTPM]":"35.6","Cell RNA - RPTEC TERT1 [nTPM]":"3.9","Cell RNA - RT4 [nTPM]":"1.7","Cell RNA - SCLC-21H [nTPM]":"1.8","Cell RNA - SH-SY5Y [nTPM]":"17.4","Cell RNA - SiHa [nTPM]":"28.3","Cell RNA - SK-BR-3 [nTPM]":"21.5","Cell RNA - SK-MEL-30 [nTPM]":"7.4","Cell RNA - SuSa [nTPM]":"6.4","Cell RNA - T-47d [nTPM]":"11.9","Cell RNA - THP-1 [nTPM]":"11.3","Cell RNA - TIME [nTPM]":"20.4","Cell RNA - U-138 MG [nTPM]":"1.3","Cell RNA - U-2 OS [nTPM]":"81.4","Cell RNA - U-2197 [nTPM]":"2.6","Cell RNA - U-251 MG [nTPM]":"16.7","Cell RNA - U-266\/70 [nTPM]":"26.8","Cell RNA - U-266\/84 [nTPM]":"24.9","Cell RNA - U-698 [nTPM]":"7.1","Cell RNA - U-87 MG [nTPM]":"35.1","Cell RNA - U-937 [nTPM]":"28.5","Cell RNA - WM-115 [nTPM]":"20.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"8.1","Blood RNA - intermediate monocyte [nTPM]":"2.4","Blood RNA - MAIT T-cell [nTPM]":"5.5","Blood RNA - memory B-cell [nTPM]":"3.5","Blood RNA - memory CD4 T-cell [nTPM]":"7.7","Blood RNA - memory CD8 T-cell [nTPM]":"6.5","Blood RNA - myeloid DC [nTPM]":"2.7","Blood RNA - naive B-cell [nTPM]":"2.0","Blood RNA - naive CD4 T-cell [nTPM]":"3.2","Blood RNA - naive CD8 T-cell [nTPM]":"3.4","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"3.0","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"5.0","Blood RNA - T-reg [nTPM]":"5.5","Blood RNA - total PBMC [nTPM]":"2.3","Brain RNA - amygdala [nTPM]":"11.3","Brain RNA - basal ganglia [nTPM]":"10.9","Brain RNA - cerebellum [nTPM]":"1.7","Brain RNA - cerebral cortex [nTPM]":"13.3","Brain RNA - hippocampal formation [nTPM]":"10.7","Brain RNA - hypothalamus [nTPM]":"14.2","Brain RNA - medulla oblongata [nTPM]":"16.2","Brain RNA - midbrain [nTPM]":"10.3","Brain RNA - pons [nTPM]":"16.4","Brain RNA - spinal cord [nTPM]":"11.3","Brain RNA - thalamus [nTPM]":"14.2","Brain RNA - white matter [nTPM]":"15.3","Single Cell Type RNA - Adipocytes [nTPM]":"84.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.1","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"11.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"57.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"30.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"62.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"56.3","Single Cell Type RNA - Bipolar cells [nTPM]":"60.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"18.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - dendritic cells [nTPM]":"12.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"38.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.3","Single Cell Type RNA - Early spermatids [nTPM]":"11.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"154.7","Single Cell Type RNA - Endothelial cells [nTPM]":"29.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"12.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.6","Single Cell Type RNA - Fibroblasts [nTPM]":"327.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"37.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.2","Single Cell Type RNA - granulocytes [nTPM]":"10.2","Single Cell Type RNA - Granulosa cells [nTPM]":"13.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"102.4","Single Cell Type RNA - Hepatocytes [nTPM]":"3.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.5","Single Cell Type RNA - Horizontal cells [nTPM]":"40.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"42.2","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"6.4","Single Cell Type RNA - Langerhans cells [nTPM]":"39.6","Single Cell Type RNA - Late spermatids [nTPM]":"39.0","Single Cell Type RNA - Leydig cells [nTPM]":"972.3","Single Cell Type RNA - Macrophages [nTPM]":"13.9","Single Cell Type RNA - Melanocytes [nTPM]":"58.7","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"9.5","Single Cell Type RNA - Muller glia cells [nTPM]":"3.5","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.9","Single Cell Type RNA - Paneth cells [nTPM]":"16.6","Single Cell Type RNA - Peritubular cells [nTPM]":"624.4","Single Cell Type RNA - Plasma cells [nTPM]":"16.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"97.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.2","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"229.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"52.8","Single Cell Type RNA - Spermatocytes [nTPM]":"50.7","Single Cell Type RNA - Spermatogonia [nTPM]":"36.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"38.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"29.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - T-cells [nTPM]":"24.9","Single Cell Type RNA - Theca cells [nTPM]":"10.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"36.4","Single Cell Type RNA - Urothelial cells [nTPM]":"27.2"},{"Gene":"MPLKIP","Gene synonym":["C7orf11","ORF20","TTDN1"],"Ensembl":"ENSG00000168303","Gene description":"M-phase specific PLK1 interacting protein","Uniprot":["Q8TAP9"],"Chromosome":"7","Position":"40126027-40134622","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Mitosis"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058457","HPA065463"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus","Vesicles"],"Antibody RRID":{"HPA058457":"AB_2683724","HPA065463":"AB_2685493"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.08e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.9","Tissue RNA - adrenal gland [nTPM]":"3.8","Tissue RNA - amygdala [nTPM]":"2.6","Tissue RNA - appendix [nTPM]":"2.0","Tissue RNA - basal ganglia [nTPM]":"2.6","Tissue RNA - bone marrow [nTPM]":"2.4","Tissue RNA - breast [nTPM]":"2.8","Tissue RNA - cerebellum [nTPM]":"4.7","Tissue RNA - cerebral cortex [nTPM]":"3.0","Tissue RNA - cervix [nTPM]":"2.8","Tissue RNA - choroid plexus [nTPM]":"3.0","Tissue RNA - colon [nTPM]":"2.8","Tissue RNA - duodenum [nTPM]":"2.2","Tissue RNA - endometrium 1 [nTPM]":"2.6","Tissue RNA - epididymis [nTPM]":"2.0","Tissue RNA - esophagus [nTPM]":"3.1","Tissue RNA - fallopian tube [nTPM]":"2.5","Tissue RNA - gallbladder [nTPM]":"1.2","Tissue RNA - heart muscle [nTPM]":"2.1","Tissue RNA - hippocampal formation [nTPM]":"2.6","Tissue RNA - hypothalamus [nTPM]":"2.3","Tissue RNA - kidney [nTPM]":"4.2","Tissue RNA - liver [nTPM]":"8.0","Tissue RNA - lung [nTPM]":"2.1","Tissue RNA - lymph node [nTPM]":"2.6","Tissue RNA - medulla oblongata [nTPM]":"2.4","Tissue RNA - midbrain [nTPM]":"2.3","Tissue RNA - ovary [nTPM]":"2.8","Tissue RNA - pancreas [nTPM]":"2.9","Tissue RNA - parathyroid gland [nTPM]":"2.5","Tissue RNA - pituitary gland [nTPM]":"3.0","Tissue RNA - placenta [nTPM]":"1.8","Tissue RNA - pons [nTPM]":"2.6","Tissue RNA - prostate [nTPM]":"2.5","Tissue RNA - rectum [nTPM]":"1.8","Tissue RNA - retina [nTPM]":"3.1","Tissue RNA - salivary gland [nTPM]":"2.7","Tissue RNA - seminal vesicle [nTPM]":"1.5","Tissue RNA - skeletal muscle [nTPM]":"2.4","Tissue RNA - skin 1 [nTPM]":"3.0","Tissue RNA - small intestine [nTPM]":"2.6","Tissue RNA - smooth muscle [nTPM]":"1.1","Tissue RNA - spinal cord [nTPM]":"2.0","Tissue RNA - spleen [nTPM]":"3.1","Tissue RNA - stomach 1 [nTPM]":"2.4","Tissue RNA - testis [nTPM]":"2.3","Tissue RNA - thalamus [nTPM]":"2.5","Tissue RNA - thymus [nTPM]":"3.3","Tissue RNA - thyroid gland [nTPM]":"3.0","Tissue RNA - tongue [nTPM]":"1.4","Tissue RNA - tonsil [nTPM]":"2.0","Tissue RNA - urinary bladder [nTPM]":"2.5","Tissue RNA - vagina [nTPM]":"2.7","Tissue RNA - white matter [nTPM]":"4.0","Cell RNA - A-431 [nTPM]":"8.2","Cell RNA - A549 [nTPM]":"2.5","Cell RNA - AF22 [nTPM]":"4.8","Cell RNA - AN3-CA [nTPM]":"6.6","Cell RNA - ASC diff [nTPM]":"4.3","Cell RNA - ASC TERT1 [nTPM]":"4.9","Cell RNA - BEWO [nTPM]":"4.9","Cell RNA - BJ [nTPM]":"3.1","Cell RNA - BJ hTERT+ [nTPM]":"3.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.3","Cell RNA - CACO-2 [nTPM]":"3.1","Cell RNA - CAPAN-2 [nTPM]":"4.0","Cell RNA - Daudi [nTPM]":"6.8","Cell RNA - EFO-21 [nTPM]":"4.2","Cell RNA - fHDF\/TERT166 [nTPM]":"3.0","Cell RNA - GAMG [nTPM]":"8.7","Cell RNA - HaCaT [nTPM]":"10.3","Cell RNA - HAP1 [nTPM]":"3.0","Cell RNA - HBEC3-KT [nTPM]":"5.3","Cell RNA - HBF TERT88 [nTPM]":"5.6","Cell RNA - HDLM-2 [nTPM]":"5.2","Cell RNA - HEK 293 [nTPM]":"9.2","Cell RNA - HEL [nTPM]":"5.4","Cell RNA - HeLa [nTPM]":"3.7","Cell RNA - Hep G2 [nTPM]":"6.9","Cell RNA - HHSteC [nTPM]":"4.9","Cell RNA - HL-60 [nTPM]":"6.7","Cell RNA - HMC-1 [nTPM]":"5.2","Cell RNA - HSkMC [nTPM]":"4.8","Cell RNA - hTCEpi [nTPM]":"6.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.4","Cell RNA - hTERT-HME1 [nTPM]":"4.1","Cell RNA - hTERT-RPE1 [nTPM]":"4.5","Cell RNA - HUVEC TERT2 [nTPM]":"5.1","Cell RNA - JURKAT [nTPM]":"7.5","Cell RNA - K-562 [nTPM]":"13.1","Cell RNA - Karpas-707 [nTPM]":"5.5","Cell RNA - LHCN-M2 [nTPM]":"4.4","Cell RNA - MCF7 [nTPM]":"4.1","Cell RNA - MOLT-4 [nTPM]":"6.8","Cell RNA - NB-4 [nTPM]":"20.4","Cell RNA - NTERA-2 [nTPM]":"6.7","Cell RNA - OE19 [nTPM]":"6.7","Cell RNA - PC-3 [nTPM]":"7.4","Cell RNA - REH [nTPM]":"9.6","Cell RNA - RH-30 [nTPM]":"3.3","Cell RNA - RPMI-8226 [nTPM]":"8.9","Cell RNA - RPTEC TERT1 [nTPM]":"5.0","Cell RNA - RT4 [nTPM]":"2.1","Cell RNA - SCLC-21H [nTPM]":"7.1","Cell RNA - SH-SY5Y [nTPM]":"8.4","Cell RNA - SiHa [nTPM]":"5.0","Cell RNA - SK-BR-3 [nTPM]":"4.8","Cell RNA - SK-MEL-30 [nTPM]":"7.7","Cell RNA - SuSa [nTPM]":"6.2","Cell RNA - T-47d [nTPM]":"6.1","Cell RNA - THP-1 [nTPM]":"9.3","Cell RNA - TIME [nTPM]":"5.5","Cell RNA - U-138 MG [nTPM]":"2.8","Cell RNA - U-2 OS [nTPM]":"7.5","Cell RNA - U-2197 [nTPM]":"3.6","Cell RNA - U-251 MG [nTPM]":"4.7","Cell RNA - U-266\/70 [nTPM]":"8.6","Cell RNA - U-266\/84 [nTPM]":"9.6","Cell RNA - U-698 [nTPM]":"10.9","Cell RNA - U-87 MG [nTPM]":"4.4","Cell RNA - U-937 [nTPM]":"10.5","Cell RNA - WM-115 [nTPM]":"7.6","Blood RNA - basophil [nTPM]":"20.6","Blood RNA - classical monocyte [nTPM]":"11.2","Blood RNA - eosinophil [nTPM]":"16.8","Blood RNA - gdT-cell [nTPM]":"8.0","Blood RNA - intermediate monocyte [nTPM]":"10.8","Blood RNA - MAIT T-cell [nTPM]":"9.0","Blood RNA - memory B-cell [nTPM]":"16.9","Blood RNA - memory CD4 T-cell [nTPM]":"10.1","Blood RNA - memory CD8 T-cell [nTPM]":"9.4","Blood RNA - myeloid DC [nTPM]":"11.8","Blood RNA - naive B-cell [nTPM]":"15.3","Blood RNA - naive CD4 T-cell [nTPM]":"11.3","Blood RNA - naive CD8 T-cell [nTPM]":"9.9","Blood RNA - neutrophil [nTPM]":"9.2","Blood RNA - NK-cell [nTPM]":"10.6","Blood RNA - non-classical monocyte [nTPM]":"10.4","Blood RNA - plasmacytoid DC [nTPM]":"13.1","Blood RNA - T-reg [nTPM]":"14.2","Blood RNA - total PBMC [nTPM]":"13.1","Brain RNA - amygdala [nTPM]":"2.6","Brain RNA - basal ganglia [nTPM]":"2.6","Brain RNA - cerebellum [nTPM]":"4.7","Brain RNA - cerebral cortex [nTPM]":"3.0","Brain RNA - hippocampal formation [nTPM]":"2.6","Brain RNA - hypothalamus [nTPM]":"2.3","Brain RNA - medulla oblongata [nTPM]":"2.4","Brain RNA - midbrain [nTPM]":"2.3","Brain RNA - pons [nTPM]":"2.6","Brain RNA - spinal cord [nTPM]":"2.0","Brain RNA - thalamus [nTPM]":"2.5","Brain RNA - white matter [nTPM]":"4.0","Single Cell Type RNA - Adipocytes [nTPM]":"49.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"34.5","Single Cell Type RNA - Astrocytes [nTPM]":"6.5","Single Cell Type RNA - B-cells [nTPM]":"53.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"110.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"96.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"151.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"58.6","Single Cell Type RNA - Bipolar cells [nTPM]":"43.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"53.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"66.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"67.2","Single Cell Type RNA - Club cells [nTPM]":"79.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"58.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"110.8","Single Cell Type RNA - dendritic cells [nTPM]":"41.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"60.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"117.4","Single Cell Type RNA - Ductal cells [nTPM]":"66.6","Single Cell Type RNA - Early spermatids [nTPM]":"118.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"73.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"62.3","Single Cell Type RNA - Endothelial cells [nTPM]":"58.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"48.6","Single Cell Type RNA - Erythroid cells [nTPM]":"52.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"54.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"79.7","Single Cell Type RNA - Fibroblasts [nTPM]":"51.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"35.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"56.6","Single Cell Type RNA - granulocytes [nTPM]":"51.3","Single Cell Type RNA - Granulosa cells [nTPM]":"63.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"47.2","Single Cell Type RNA - Hepatocytes [nTPM]":"133.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"69.0","Single Cell Type RNA - Horizontal cells [nTPM]":"53.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"63.4","Single Cell Type RNA - Ionocytes [nTPM]":"85.5","Single Cell Type RNA - Kupffer cells [nTPM]":"59.3","Single Cell Type RNA - Langerhans cells [nTPM]":"62.6","Single Cell Type RNA - Late spermatids [nTPM]":"38.6","Single Cell Type RNA - Leydig cells [nTPM]":"75.8","Single Cell Type RNA - Macrophages [nTPM]":"50.4","Single Cell Type RNA - Melanocytes [nTPM]":"58.7","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"74.6","Single Cell Type RNA - Muller glia cells [nTPM]":"52.9","Single Cell Type RNA - NK-cells [nTPM]":"66.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"59.9","Single Cell Type RNA - Paneth cells [nTPM]":"97.2","Single Cell Type RNA - Peritubular cells [nTPM]":"55.3","Single Cell Type RNA - Plasma cells [nTPM]":"36.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"76.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"61.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"190.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"91.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"50.1","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"57.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"58.4","Single Cell Type RNA - Spermatocytes [nTPM]":"66.6","Single Cell Type RNA - Spermatogonia [nTPM]":"53.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"67.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"134.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"95.6","Single Cell Type RNA - T-cells [nTPM]":"46.8","Single Cell Type RNA - Theca cells [nTPM]":"125.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"82.3","Single Cell Type RNA - Urothelial cells [nTPM]":"105.7"},{"Gene":"NCSTN","Gene synonym":["APH2","KIAA0253"],"Ensembl":"ENSG00000162736","Gene description":"Nicastrin","Uniprot":["Q92542"],"Chromosome":"1","Position":"160343316-160358952","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Notch signaling pathway"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"147.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB021982","HPA054846","HPA070642"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"130000","Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB021982":null,"HPA054846":"AB_2682624","HPA070642":"AB_2686289"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.75e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-2"},"Tissue RNA - adipose tissue [nTPM]":"51.0","Tissue RNA - adrenal gland [nTPM]":"36.6","Tissue RNA - amygdala [nTPM]":"30.6","Tissue RNA - appendix [nTPM]":"42.1","Tissue RNA - basal ganglia [nTPM]":"36.1","Tissue RNA - bone marrow [nTPM]":"38.1","Tissue RNA - breast [nTPM]":"43.9","Tissue RNA - cerebellum [nTPM]":"38.5","Tissue RNA - cerebral cortex [nTPM]":"32.5","Tissue RNA - cervix [nTPM]":"52.4","Tissue RNA - choroid plexus [nTPM]":"42.0","Tissue RNA - colon [nTPM]":"58.4","Tissue RNA - duodenum [nTPM]":"80.4","Tissue RNA - endometrium 1 [nTPM]":"40.3","Tissue RNA - epididymis [nTPM]":"56.4","Tissue RNA - esophagus [nTPM]":"35.1","Tissue RNA - fallopian tube [nTPM]":"49.7","Tissue RNA - gallbladder [nTPM]":"42.9","Tissue RNA - heart muscle [nTPM]":"50.6","Tissue RNA - hippocampal formation [nTPM]":"29.9","Tissue RNA - hypothalamus [nTPM]":"35.8","Tissue RNA - kidney [nTPM]":"59.7","Tissue RNA - liver [nTPM]":"59.3","Tissue RNA - lung [nTPM]":"56.0","Tissue RNA - lymph node [nTPM]":"38.3","Tissue RNA - medulla oblongata [nTPM]":"40.0","Tissue RNA - midbrain [nTPM]":"34.0","Tissue RNA - ovary [nTPM]":"51.7","Tissue RNA - pancreas [nTPM]":"63.8","Tissue RNA - parathyroid gland [nTPM]":"86.0","Tissue RNA - pituitary gland [nTPM]":"30.1","Tissue RNA - placenta [nTPM]":"98.7","Tissue RNA - pons [nTPM]":"41.6","Tissue RNA - prostate [nTPM]":"45.2","Tissue RNA - rectum [nTPM]":"60.9","Tissue RNA - retina [nTPM]":"48.1","Tissue RNA - salivary gland [nTPM]":"60.5","Tissue RNA - seminal vesicle [nTPM]":"47.3","Tissue RNA - skeletal muscle [nTPM]":"37.6","Tissue RNA - skin 1 [nTPM]":"38.9","Tissue RNA - small intestine [nTPM]":"63.5","Tissue RNA - smooth muscle [nTPM]":"52.1","Tissue RNA - spinal cord [nTPM]":"37.3","Tissue RNA - spleen [nTPM]":"46.2","Tissue RNA - stomach 1 [nTPM]":"45.7","Tissue RNA - testis [nTPM]":"41.8","Tissue RNA - thalamus [nTPM]":"36.4","Tissue RNA - thymus [nTPM]":"40.0","Tissue RNA - thyroid gland [nTPM]":"63.8","Tissue RNA - tongue [nTPM]":"38.4","Tissue RNA - tonsil [nTPM]":"43.0","Tissue RNA - urinary bladder [nTPM]":"45.6","Tissue RNA - vagina [nTPM]":"31.5","Tissue RNA - white matter [nTPM]":"48.9","Cell RNA - A-431 [nTPM]":"52.1","Cell RNA - A549 [nTPM]":"57.4","Cell RNA - AF22 [nTPM]":"100.4","Cell RNA - AN3-CA [nTPM]":"82.8","Cell RNA - ASC diff [nTPM]":"301.0","Cell RNA - ASC TERT1 [nTPM]":"153.4","Cell RNA - BEWO [nTPM]":"108.3","Cell RNA - BJ [nTPM]":"104.0","Cell RNA - BJ hTERT+ [nTPM]":"177.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"95.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"109.9","Cell RNA - CACO-2 [nTPM]":"47.9","Cell RNA - CAPAN-2 [nTPM]":"140.0","Cell RNA - Daudi [nTPM]":"36.6","Cell RNA - EFO-21 [nTPM]":"208.6","Cell RNA - fHDF\/TERT166 [nTPM]":"209.3","Cell RNA - GAMG [nTPM]":"67.1","Cell RNA - HaCaT [nTPM]":"81.5","Cell RNA - HAP1 [nTPM]":"47.3","Cell RNA - HBEC3-KT [nTPM]":"95.9","Cell RNA - HBF TERT88 [nTPM]":"82.4","Cell RNA - HDLM-2 [nTPM]":"56.5","Cell RNA - HEK 293 [nTPM]":"42.3","Cell RNA - HEL [nTPM]":"36.6","Cell RNA - HeLa [nTPM]":"70.9","Cell RNA - Hep G2 [nTPM]":"70.0","Cell RNA - HHSteC [nTPM]":"118.6","Cell RNA - HL-60 [nTPM]":"82.8","Cell RNA - HMC-1 [nTPM]":"152.0","Cell RNA - HSkMC [nTPM]":"155.7","Cell RNA - hTCEpi [nTPM]":"92.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"94.3","Cell RNA - hTERT-HME1 [nTPM]":"93.6","Cell RNA - hTERT-RPE1 [nTPM]":"207.2","Cell RNA - HUVEC TERT2 [nTPM]":"139.9","Cell RNA - JURKAT [nTPM]":"54.3","Cell RNA - K-562 [nTPM]":"66.9","Cell RNA - Karpas-707 [nTPM]":"100.2","Cell RNA - LHCN-M2 [nTPM]":"142.2","Cell RNA - MCF7 [nTPM]":"34.3","Cell RNA - MOLT-4 [nTPM]":"26.8","Cell RNA - NB-4 [nTPM]":"39.8","Cell RNA - NTERA-2 [nTPM]":"82.2","Cell RNA - OE19 [nTPM]":"130.6","Cell RNA - PC-3 [nTPM]":"33.8","Cell RNA - REH [nTPM]":"35.1","Cell RNA - RH-30 [nTPM]":"59.9","Cell RNA - RPMI-8226 [nTPM]":"103.6","Cell RNA - RPTEC TERT1 [nTPM]":"130.5","Cell RNA - RT4 [nTPM]":"69.9","Cell RNA - SCLC-21H [nTPM]":"34.2","Cell RNA - SH-SY5Y [nTPM]":"75.6","Cell RNA - SiHa [nTPM]":"109.1","Cell RNA - SK-BR-3 [nTPM]":"118.5","Cell RNA - SK-MEL-30 [nTPM]":"70.9","Cell RNA - SuSa [nTPM]":"158.0","Cell RNA - T-47d [nTPM]":"108.2","Cell RNA - THP-1 [nTPM]":"186.3","Cell RNA - TIME [nTPM]":"125.5","Cell RNA - U-138 MG [nTPM]":"70.3","Cell RNA - U-2 OS [nTPM]":"46.4","Cell RNA - U-2197 [nTPM]":"48.8","Cell RNA - U-251 MG [nTPM]":"79.9","Cell RNA - U-266\/70 [nTPM]":"130.8","Cell RNA - U-266\/84 [nTPM]":"194.4","Cell RNA - U-698 [nTPM]":"38.6","Cell RNA - U-87 MG [nTPM]":"106.6","Cell RNA - U-937 [nTPM]":"49.8","Cell RNA - WM-115 [nTPM]":"129.4","Blood RNA - basophil [nTPM]":"71.4","Blood RNA - classical monocyte [nTPM]":"79.0","Blood RNA - eosinophil [nTPM]":"67.8","Blood RNA - gdT-cell [nTPM]":"27.4","Blood RNA - intermediate monocyte [nTPM]":"79.0","Blood RNA - MAIT T-cell [nTPM]":"26.2","Blood RNA - memory B-cell [nTPM]":"31.1","Blood RNA - memory CD4 T-cell [nTPM]":"23.5","Blood RNA - memory CD8 T-cell [nTPM]":"24.0","Blood RNA - myeloid DC [nTPM]":"75.1","Blood RNA - naive B-cell [nTPM]":"27.8","Blood RNA - naive CD4 T-cell [nTPM]":"23.9","Blood RNA - naive CD8 T-cell [nTPM]":"23.3","Blood RNA - neutrophil [nTPM]":"69.2","Blood RNA - NK-cell [nTPM]":"36.6","Blood RNA - non-classical monocyte [nTPM]":"79.6","Blood RNA - plasmacytoid DC [nTPM]":"45.1","Blood RNA - T-reg [nTPM]":"26.5","Blood RNA - total PBMC [nTPM]":"52.2","Brain RNA - amygdala [nTPM]":"30.6","Brain RNA - basal ganglia [nTPM]":"36.1","Brain RNA - cerebellum [nTPM]":"38.5","Brain RNA - cerebral cortex [nTPM]":"32.5","Brain RNA - hippocampal formation [nTPM]":"29.9","Brain RNA - hypothalamus [nTPM]":"35.8","Brain RNA - medulla oblongata [nTPM]":"40.0","Brain RNA - midbrain [nTPM]":"34.0","Brain RNA - pons [nTPM]":"41.6","Brain RNA - spinal cord [nTPM]":"37.3","Brain RNA - thalamus [nTPM]":"36.4","Brain RNA - white matter [nTPM]":"48.9","Single Cell Type RNA - Adipocytes [nTPM]":"28.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"23.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"59.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Bipolar cells [nTPM]":"20.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"27.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"45.8","Single Cell Type RNA - Club cells [nTPM]":"42.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"53.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"107.7","Single Cell Type RNA - dendritic cells [nTPM]":"27.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"53.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"38.9","Single Cell Type RNA - Early spermatids [nTPM]":"2.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.7","Single Cell Type RNA - Endothelial cells [nTPM]":"23.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.3","Single Cell Type RNA - Erythroid cells [nTPM]":"17.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"27.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"95.7","Single Cell Type RNA - Fibroblasts [nTPM]":"33.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"30.2","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"25.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"29.6","Single Cell Type RNA - Hepatocytes [nTPM]":"31.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"58.0","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.8","Single Cell Type RNA - Ionocytes [nTPM]":"46.8","Single Cell Type RNA - Kupffer cells [nTPM]":"47.1","Single Cell Type RNA - Langerhans cells [nTPM]":"18.8","Single Cell Type RNA - Late spermatids [nTPM]":"4.7","Single Cell Type RNA - Leydig cells [nTPM]":"27.1","Single Cell Type RNA - Macrophages [nTPM]":"33.4","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"31.7","Single Cell Type RNA - Muller glia cells [nTPM]":"35.0","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"34.8","Single Cell Type RNA - Paneth cells [nTPM]":"33.4","Single Cell Type RNA - Peritubular cells [nTPM]":"21.1","Single Cell Type RNA - Plasma cells [nTPM]":"33.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"66.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"26.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.6","Single Cell Type RNA - Spermatocytes [nTPM]":"44.6","Single Cell Type RNA - Spermatogonia [nTPM]":"35.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"147.4","Single Cell Type RNA - T-cells [nTPM]":"16.5","Single Cell Type RNA - Theca cells [nTPM]":"32.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"29.6","Single Cell Type RNA - Urothelial cells [nTPM]":"20.5"},{"Gene":"NLRP1","Gene synonym":["CARD7","CLR17.1","DEFCAP","DKFZp586O1822","KIAA0926","NAC","NALP1","SLEV1","VAMAS1"],"Ensembl":"ENSG00000091592","Gene description":"NLR family pyrin domain containing 1","Uniprot":["Q9C000"],"Chromosome":"17","Position":"5499427-5619424","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Host-virus interaction","Immunity","Inflammatory response","Innate immunity","Necrosis"],"Molecular function":["Hydrolase","Protease"],"Disease involvement":["Disease variant","Ectodermal dysplasia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"561.7","Muller glia cells":"151.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"20.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"55.4","Karpas-707":"90.9","U-266\/70":"45.0"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009189","HPA064431"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 23: Spermatids - Flagellum & Golgi organization","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB009189":null,"HPA064431":"AB_2685262"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.57e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.60e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Tissue RNA - adipose tissue [nTPM]":"27.9","Tissue RNA - adrenal gland [nTPM]":"4.0","Tissue RNA - amygdala [nTPM]":"3.6","Tissue RNA - appendix [nTPM]":"27.8","Tissue RNA - basal ganglia [nTPM]":"3.7","Tissue RNA - bone marrow [nTPM]":"25.0","Tissue RNA - breast [nTPM]":"22.1","Tissue RNA - cerebellum [nTPM]":"3.2","Tissue RNA - cerebral cortex [nTPM]":"5.3","Tissue RNA - cervix [nTPM]":"22.9","Tissue RNA - choroid plexus [nTPM]":"3.5","Tissue RNA - colon [nTPM]":"10.8","Tissue RNA - duodenum [nTPM]":"5.8","Tissue RNA - endometrium 1 [nTPM]":"13.8","Tissue RNA - epididymis [nTPM]":"1.8","Tissue RNA - esophagus [nTPM]":"16.2","Tissue RNA - fallopian tube [nTPM]":"14.4","Tissue RNA - gallbladder [nTPM]":"13.4","Tissue RNA - heart muscle [nTPM]":"15.7","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"3.7","Tissue RNA - kidney [nTPM]":"9.4","Tissue RNA - liver [nTPM]":"5.3","Tissue RNA - lung [nTPM]":"26.9","Tissue RNA - lymph node [nTPM]":"38.1","Tissue RNA - medulla oblongata [nTPM]":"5.5","Tissue RNA - midbrain [nTPM]":"3.8","Tissue RNA - ovary [nTPM]":"5.8","Tissue RNA - pancreas [nTPM]":"3.2","Tissue RNA - parathyroid gland [nTPM]":"1.8","Tissue RNA - pituitary gland [nTPM]":"4.1","Tissue RNA - placenta [nTPM]":"12.1","Tissue RNA - pons [nTPM]":"5.5","Tissue RNA - prostate [nTPM]":"13.2","Tissue RNA - rectum [nTPM]":"7.8","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"10.8","Tissue RNA - seminal vesicle [nTPM]":"9.0","Tissue RNA - skeletal muscle [nTPM]":"7.7","Tissue RNA - skin 1 [nTPM]":"50.8","Tissue RNA - small intestine [nTPM]":"31.1","Tissue RNA - smooth muscle [nTPM]":"9.7","Tissue RNA - spinal cord [nTPM]":"3.7","Tissue RNA - spleen [nTPM]":"56.3","Tissue RNA - stomach 1 [nTPM]":"6.9","Tissue RNA - testis [nTPM]":"6.1","Tissue RNA - thalamus [nTPM]":"4.0","Tissue RNA - thymus [nTPM]":"15.1","Tissue RNA - thyroid gland [nTPM]":"21.8","Tissue RNA - tongue [nTPM]":"7.7","Tissue RNA - tonsil [nTPM]":"32.4","Tissue RNA - urinary bladder [nTPM]":"15.8","Tissue RNA - vagina [nTPM]":"27.7","Tissue RNA - white matter [nTPM]":"4.1","Cell RNA - A-431 [nTPM]":"14.2","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"8.6","Cell RNA - ASC TERT1 [nTPM]":"10.2","Cell RNA - BEWO [nTPM]":"1.8","Cell RNA - BJ [nTPM]":"6.9","Cell RNA - BJ hTERT+ [nTPM]":"6.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.7","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"5.5","Cell RNA - Daudi [nTPM]":"5.3","Cell RNA - EFO-21 [nTPM]":"20.8","Cell RNA - fHDF\/TERT166 [nTPM]":"7.6","Cell RNA - GAMG [nTPM]":"1.1","Cell RNA - HaCaT [nTPM]":"6.5","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"23.4","Cell RNA - HBF TERT88 [nTPM]":"4.0","Cell RNA - HDLM-2 [nTPM]":"55.4","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"1.4","Cell RNA - HeLa [nTPM]":"4.8","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"7.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.6","Cell RNA - HSkMC [nTPM]":"6.6","Cell RNA - hTCEpi [nTPM]":"14.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.7","Cell RNA - hTERT-HME1 [nTPM]":"13.7","Cell RNA - hTERT-RPE1 [nTPM]":"10.4","Cell RNA - HUVEC TERT2 [nTPM]":"25.6","Cell RNA - JURKAT [nTPM]":"1.1","Cell RNA - K-562 [nTPM]":"13.0","Cell RNA - Karpas-707 [nTPM]":"90.9","Cell RNA - LHCN-M2 [nTPM]":"11.8","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"4.6","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"6.0","Cell RNA - RH-30 [nTPM]":"4.0","Cell RNA - RPMI-8226 [nTPM]":"23.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"4.8","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"0.6","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"25.2","Cell RNA - U-138 MG [nTPM]":"5.3","Cell RNA - U-2 OS [nTPM]":"3.0","Cell RNA - U-2197 [nTPM]":"3.2","Cell RNA - U-251 MG [nTPM]":"1.1","Cell RNA - U-266\/70 [nTPM]":"45.0","Cell RNA - U-266\/84 [nTPM]":"15.9","Cell RNA - U-698 [nTPM]":"4.1","Cell RNA - U-87 MG [nTPM]":"8.7","Cell RNA - U-937 [nTPM]":"0.6","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"18.3","Blood RNA - classical monocyte [nTPM]":"7.1","Blood RNA - eosinophil [nTPM]":"5.0","Blood RNA - gdT-cell [nTPM]":"5.9","Blood RNA - intermediate monocyte [nTPM]":"4.9","Blood RNA - MAIT T-cell [nTPM]":"6.6","Blood RNA - memory B-cell [nTPM]":"4.4","Blood RNA - memory CD4 T-cell [nTPM]":"5.1","Blood RNA - memory CD8 T-cell [nTPM]":"6.3","Blood RNA - myeloid DC [nTPM]":"5.0","Blood RNA - naive B-cell [nTPM]":"4.9","Blood RNA - naive CD4 T-cell [nTPM]":"5.5","Blood RNA - naive CD8 T-cell [nTPM]":"5.2","Blood RNA - neutrophil [nTPM]":"18.9","Blood RNA - NK-cell [nTPM]":"4.2","Blood RNA - non-classical monocyte [nTPM]":"8.6","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"7.7","Blood RNA - total PBMC [nTPM]":"4.6","Brain RNA - amygdala [nTPM]":"3.6","Brain RNA - basal ganglia [nTPM]":"3.7","Brain RNA - cerebellum [nTPM]":"3.2","Brain RNA - cerebral cortex [nTPM]":"5.3","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"3.7","Brain RNA - medulla oblongata [nTPM]":"5.5","Brain RNA - midbrain [nTPM]":"3.8","Brain RNA - pons [nTPM]":"5.5","Brain RNA - spinal cord [nTPM]":"3.7","Brain RNA - thalamus [nTPM]":"4.0","Brain RNA - white matter [nTPM]":"4.1","Single Cell Type RNA - Adipocytes [nTPM]":"46.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.8","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"29.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Bipolar cells [nTPM]":"60.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"10.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - dendritic cells [nTPM]":"30.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"561.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.0","Single Cell Type RNA - Endothelial cells [nTPM]":"26.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"77.9","Single Cell Type RNA - Erythroid cells [nTPM]":"3.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.1","Single Cell Type RNA - Fibroblasts [nTPM]":"31.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.0","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"7.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"44.6","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.0","Single Cell Type RNA - Horizontal cells [nTPM]":"85.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"23.0","Single Cell Type RNA - Langerhans cells [nTPM]":"24.3","Single Cell Type RNA - Late spermatids [nTPM]":"93.4","Single Cell Type RNA - Leydig cells [nTPM]":"25.4","Single Cell Type RNA - Macrophages [nTPM]":"26.2","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"56.2","Single Cell Type RNA - monocytes [nTPM]":"27.0","Single Cell Type RNA - Muller glia cells [nTPM]":"151.8","Single Cell Type RNA - NK-cells [nTPM]":"26.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"28.2","Single Cell Type RNA - Plasma cells [nTPM]":"25.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"33.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.3","Single Cell Type RNA - Spermatocytes [nTPM]":"25.0","Single Cell Type RNA - Spermatogonia [nTPM]":"11.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"37.6","Single Cell Type RNA - Theca cells [nTPM]":"3.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"8.0"},{"Gene":"NOD1","Gene synonym":["CARD4","CLR7.1","NLRC1"],"Ensembl":"ENSG00000106100","Gene description":"Nucleotide binding oligomerization domain containing 1","Uniprot":["Q9Y239"],"Chromosome":"7","Position":"30424527-30478784","Protein class":["Human disease related genes","Predicted intracellular proteins"],"Biological process":["Apoptosis","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"19.3","Microglial cells":"26.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"11.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074367"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 19: Lung - Lung function","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA074367":"AB_2686683"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.68e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.95e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.6","Tissue RNA - adrenal gland [nTPM]":"2.9","Tissue RNA - amygdala [nTPM]":"3.0","Tissue RNA - appendix [nTPM]":"8.8","Tissue RNA - basal ganglia [nTPM]":"3.2","Tissue RNA - bone marrow [nTPM]":"6.8","Tissue RNA - breast [nTPM]":"9.5","Tissue RNA - cerebellum [nTPM]":"2.5","Tissue RNA - cerebral cortex [nTPM]":"2.6","Tissue RNA - cervix [nTPM]":"5.3","Tissue RNA - choroid plexus [nTPM]":"4.6","Tissue RNA - colon [nTPM]":"5.3","Tissue RNA - duodenum [nTPM]":"2.2","Tissue RNA - endometrium 1 [nTPM]":"6.1","Tissue RNA - epididymis [nTPM]":"2.6","Tissue RNA - esophagus [nTPM]":"4.7","Tissue RNA - fallopian tube [nTPM]":"6.5","Tissue RNA - gallbladder [nTPM]":"5.4","Tissue RNA - heart muscle [nTPM]":"7.3","Tissue RNA - hippocampal formation [nTPM]":"2.4","Tissue RNA - hypothalamus [nTPM]":"3.2","Tissue RNA - kidney [nTPM]":"3.9","Tissue RNA - liver [nTPM]":"2.2","Tissue RNA - lung [nTPM]":"11.9","Tissue RNA - lymph node [nTPM]":"6.1","Tissue RNA - medulla oblongata [nTPM]":"7.6","Tissue RNA - midbrain [nTPM]":"4.9","Tissue RNA - ovary [nTPM]":"10.3","Tissue RNA - pancreas [nTPM]":"1.8","Tissue RNA - parathyroid gland [nTPM]":"2.7","Tissue RNA - pituitary gland [nTPM]":"2.9","Tissue RNA - placenta [nTPM]":"12.2","Tissue RNA - pons [nTPM]":"4.7","Tissue RNA - prostate [nTPM]":"4.0","Tissue RNA - rectum [nTPM]":"4.3","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"6.2","Tissue RNA - seminal vesicle [nTPM]":"3.2","Tissue RNA - skeletal muscle [nTPM]":"4.0","Tissue RNA - skin 1 [nTPM]":"5.9","Tissue RNA - small intestine [nTPM]":"5.4","Tissue RNA - smooth muscle [nTPM]":"7.3","Tissue RNA - spinal cord [nTPM]":"3.6","Tissue RNA - spleen [nTPM]":"11.1","Tissue RNA - stomach 1 [nTPM]":"4.8","Tissue RNA - testis [nTPM]":"1.9","Tissue RNA - thalamus [nTPM]":"5.6","Tissue RNA - thymus [nTPM]":"3.5","Tissue RNA - thyroid gland [nTPM]":"10.8","Tissue RNA - tongue [nTPM]":"4.0","Tissue RNA - tonsil [nTPM]":"5.0","Tissue RNA - urinary bladder [nTPM]":"7.3","Tissue RNA - vagina [nTPM]":"5.0","Tissue RNA - white matter [nTPM]":"2.8","Cell RNA - A-431 [nTPM]":"4.8","Cell RNA - A549 [nTPM]":"2.5","Cell RNA - AF22 [nTPM]":"3.5","Cell RNA - AN3-CA [nTPM]":"10.5","Cell RNA - ASC diff [nTPM]":"2.2","Cell RNA - ASC TERT1 [nTPM]":"10.3","Cell RNA - BEWO [nTPM]":"5.3","Cell RNA - BJ [nTPM]":"3.3","Cell RNA - BJ hTERT+ [nTPM]":"2.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.0","Cell RNA - CACO-2 [nTPM]":"2.2","Cell RNA - CAPAN-2 [nTPM]":"5.7","Cell RNA - Daudi [nTPM]":"6.9","Cell RNA - EFO-21 [nTPM]":"3.8","Cell RNA - fHDF\/TERT166 [nTPM]":"4.2","Cell RNA - GAMG [nTPM]":"6.1","Cell RNA - HaCaT [nTPM]":"11.2","Cell RNA - HAP1 [nTPM]":"3.5","Cell RNA - HBEC3-KT [nTPM]":"5.8","Cell RNA - HBF TERT88 [nTPM]":"3.7","Cell RNA - HDLM-2 [nTPM]":"3.6","Cell RNA - HEK 293 [nTPM]":"3.0","Cell RNA - HEL [nTPM]":"9.7","Cell RNA - HeLa [nTPM]":"7.7","Cell RNA - Hep G2 [nTPM]":"2.2","Cell RNA - HHSteC [nTPM]":"2.8","Cell RNA - HL-60 [nTPM]":"4.3","Cell RNA - HMC-1 [nTPM]":"7.0","Cell RNA - HSkMC [nTPM]":"9.6","Cell RNA - hTCEpi [nTPM]":"2.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.5","Cell RNA - hTERT-HME1 [nTPM]":"3.0","Cell RNA - hTERT-RPE1 [nTPM]":"4.9","Cell RNA - HUVEC TERT2 [nTPM]":"18.3","Cell RNA - JURKAT [nTPM]":"10.1","Cell RNA - K-562 [nTPM]":"5.2","Cell RNA - Karpas-707 [nTPM]":"2.4","Cell RNA - LHCN-M2 [nTPM]":"5.0","Cell RNA - MCF7 [nTPM]":"2.8","Cell RNA - MOLT-4 [nTPM]":"6.2","Cell RNA - NB-4 [nTPM]":"7.7","Cell RNA - NTERA-2 [nTPM]":"4.1","Cell RNA - OE19 [nTPM]":"5.3","Cell RNA - PC-3 [nTPM]":"4.5","Cell RNA - REH [nTPM]":"7.4","Cell RNA - RH-30 [nTPM]":"4.0","Cell RNA - RPMI-8226 [nTPM]":"6.3","Cell RNA - RPTEC TERT1 [nTPM]":"1.8","Cell RNA - RT4 [nTPM]":"3.8","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"12.4","Cell RNA - SiHa [nTPM]":"4.2","Cell RNA - SK-BR-3 [nTPM]":"10.7","Cell RNA - SK-MEL-30 [nTPM]":"3.7","Cell RNA - SuSa [nTPM]":"4.8","Cell RNA - T-47d [nTPM]":"3.6","Cell RNA - THP-1 [nTPM]":"9.6","Cell RNA - TIME [nTPM]":"7.7","Cell RNA - U-138 MG [nTPM]":"4.8","Cell RNA - U-2 OS [nTPM]":"7.6","Cell RNA - U-2197 [nTPM]":"6.0","Cell RNA - U-251 MG [nTPM]":"4.5","Cell RNA - U-266\/70 [nTPM]":"2.2","Cell RNA - U-266\/84 [nTPM]":"8.0","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"3.5","Cell RNA - U-937 [nTPM]":"15.1","Cell RNA - WM-115 [nTPM]":"5.1","Blood RNA - basophil [nTPM]":"13.7","Blood RNA - classical monocyte [nTPM]":"3.7","Blood RNA - eosinophil [nTPM]":"13.5","Blood RNA - gdT-cell [nTPM]":"8.1","Blood RNA - intermediate monocyte [nTPM]":"5.0","Blood RNA - MAIT T-cell [nTPM]":"8.9","Blood RNA - memory B-cell [nTPM]":"7.5","Blood RNA - memory CD4 T-cell [nTPM]":"5.5","Blood RNA - memory CD8 T-cell [nTPM]":"5.3","Blood RNA - myeloid DC [nTPM]":"3.3","Blood RNA - naive B-cell [nTPM]":"10.9","Blood RNA - naive CD4 T-cell [nTPM]":"4.9","Blood RNA - naive CD8 T-cell [nTPM]":"4.0","Blood RNA - neutrophil [nTPM]":"2.8","Blood RNA - NK-cell [nTPM]":"8.5","Blood RNA - non-classical monocyte [nTPM]":"6.6","Blood RNA - plasmacytoid DC [nTPM]":"8.0","Blood RNA - T-reg [nTPM]":"4.8","Blood RNA - total PBMC [nTPM]":"2.6","Brain RNA - amygdala [nTPM]":"3.0","Brain RNA - basal ganglia [nTPM]":"3.2","Brain RNA - cerebellum [nTPM]":"2.5","Brain RNA - cerebral cortex [nTPM]":"2.6","Brain RNA - hippocampal formation [nTPM]":"2.4","Brain RNA - hypothalamus [nTPM]":"3.2","Brain RNA - medulla oblongata [nTPM]":"7.6","Brain RNA - midbrain [nTPM]":"4.9","Brain RNA - pons [nTPM]":"4.7","Brain RNA - spinal cord [nTPM]":"3.6","Brain RNA - thalamus [nTPM]":"5.6","Brain RNA - white matter [nTPM]":"2.8","Single Cell Type RNA - Adipocytes [nTPM]":"19.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.1","Single Cell Type RNA - Astrocytes [nTPM]":"7.2","Single Cell Type RNA - B-cells [nTPM]":"6.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"2.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"5.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.0","Single Cell Type RNA - dendritic cells [nTPM]":"6.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.7","Single Cell Type RNA - Endothelial cells [nTPM]":"12.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.3","Single Cell Type RNA - Fibroblasts [nTPM]":"8.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.6","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"7.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"1.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.5","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.1","Single Cell Type RNA - Langerhans cells [nTPM]":"3.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"4.3","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"26.2","Single Cell Type RNA - monocytes [nTPM]":"4.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.7","Single Cell Type RNA - Paneth cells [nTPM]":"1.7","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"3.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"5.3","Single Cell Type RNA - Theca cells [nTPM]":"1.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"NOD2","Gene synonym":["BLAU","CARD15","CD","CLR16.3","IBD1","NLRC2","PSORAS1"],"Ensembl":"ENSG00000167207","Gene description":"Nucleotide binding oligomerization domain containing 2","Uniprot":["Q9HC29"],"Chromosome":"16","Position":"50693588-50734041","Protein class":["Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"13.6","esophagus":"11.7","skin 1":"14.4","vagina":"12.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"8.3","Kupffer cells":"9.0","Langerhans cells":"22.5","Macrophages":"15.2","monocytes":"15.6","Suprabasal keratinocytes":"15.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"23.0","eosinophil":"6.0","intermediate monocyte":"13.1","myeloid DC":"21.3","neutrophil":"10.5","non-classical monocyte":"9.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"21.3","granulocytes":"10.5","monocytes":"23.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"11.6","T-47d":"5.8","THP-1":"7.3","U-266\/70":"15.9","U-266\/84":"7.2"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041985","HPA054494"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA041985":"AB_2677780","HPA054494":"AB_2682505"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.91e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.94e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.5","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"5.9","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"13.6","Tissue RNA - breast [nTPM]":"1.5","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"1.0","Tissue RNA - cervix [nTPM]":"5.6","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"0.9","Tissue RNA - duodenum [nTPM]":"1.5","Tissue RNA - endometrium 1 [nTPM]":"0.6","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"11.7","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"1.3","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.4","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"1.7","Tissue RNA - lung [nTPM]":"4.3","Tissue RNA - lymph node [nTPM]":"2.7","Tissue RNA - medulla oblongata [nTPM]":"1.0","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.4","Tissue RNA - placenta [nTPM]":"1.2","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"0.9","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"4.3","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"14.4","Tissue RNA - small intestine [nTPM]":"1.3","Tissue RNA - smooth muscle [nTPM]":"1.8","Tissue RNA - spinal cord [nTPM]":"0.7","Tissue RNA - spleen [nTPM]":"4.4","Tissue RNA - stomach 1 [nTPM]":"1.4","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"1.4","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"2.3","Tissue RNA - urinary bladder [nTPM]":"1.6","Tissue RNA - vagina [nTPM]":"12.3","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"0.6","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1.4","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"11.6","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"2.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"2.8","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"3.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"1.5","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"5.8","Cell RNA - THP-1 [nTPM]":"7.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"15.9","Cell RNA - U-266\/84 [nTPM]":"7.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"3.0","Blood RNA - classical monocyte [nTPM]":"23.0","Blood RNA - eosinophil [nTPM]":"6.0","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"13.1","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"21.3","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"10.5","Blood RNA - NK-cell [nTPM]":"3.4","Blood RNA - non-classical monocyte [nTPM]":"9.0","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"0.9","Blood RNA - total PBMC [nTPM]":"11.1","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"1.0","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.4","Brain RNA - medulla oblongata [nTPM]":"1.0","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.7","Brain RNA - thalamus [nTPM]":"1.4","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"2.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.8","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"9.0","Single Cell Type RNA - Langerhans cells [nTPM]":"22.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"15.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"15.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"4.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"2.3","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"NOTCH3","Gene synonym":["CADASIL","CASIL"],"Ensembl":"ENSG00000074181","Gene description":"Notch receptor 3","Uniprot":["Q9UM47"],"Chromosome":"19","Position":"15159038-15200995","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Notch signaling pathway","Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Sertoli cells":"414.2","Skeletal myocytes":"131.6","Smooth muscle cells":"317.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"66.3","MCF7":"66.9","RT4":"41.2","U-87 MG":"45.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005393","HPA044392"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"46000000","Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Actin filaments"],"Antibody RRID":{"CAB005393":"AB_2151246","HPA044392":"AB_2678926"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.92e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.53e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-3"},"Tissue RNA - adipose tissue [nTPM]":"85.7","Tissue RNA - adrenal gland [nTPM]":"5.3","Tissue RNA - amygdala [nTPM]":"14.8","Tissue RNA - appendix [nTPM]":"10.4","Tissue RNA - basal ganglia [nTPM]":"12.4","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"50.5","Tissue RNA - cerebellum [nTPM]":"11.0","Tissue RNA - cerebral cortex [nTPM]":"21.3","Tissue RNA - cervix [nTPM]":"49.4","Tissue RNA - choroid plexus [nTPM]":"7.1","Tissue RNA - colon [nTPM]":"14.8","Tissue RNA - duodenum [nTPM]":"5.5","Tissue RNA - endometrium 1 [nTPM]":"39.9","Tissue RNA - epididymis [nTPM]":"16.9","Tissue RNA - esophagus [nTPM]":"74.3","Tissue RNA - fallopian tube [nTPM]":"35.8","Tissue RNA - gallbladder [nTPM]":"23.5","Tissue RNA - heart muscle [nTPM]":"43.6","Tissue RNA - hippocampal formation [nTPM]":"9.5","Tissue RNA - hypothalamus [nTPM]":"11.3","Tissue RNA - kidney [nTPM]":"26.0","Tissue RNA - liver [nTPM]":"3.2","Tissue RNA - lung [nTPM]":"38.3","Tissue RNA - lymph node [nTPM]":"9.2","Tissue RNA - medulla oblongata [nTPM]":"12.0","Tissue RNA - midbrain [nTPM]":"15.2","Tissue RNA - ovary [nTPM]":"18.9","Tissue RNA - pancreas [nTPM]":"10.7","Tissue RNA - parathyroid gland [nTPM]":"12.6","Tissue RNA - pituitary gland [nTPM]":"10.3","Tissue RNA - placenta [nTPM]":"59.8","Tissue RNA - pons [nTPM]":"14.3","Tissue RNA - prostate [nTPM]":"22.0","Tissue RNA - rectum [nTPM]":"4.2","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"24.4","Tissue RNA - seminal vesicle [nTPM]":"16.5","Tissue RNA - skeletal muscle [nTPM]":"29.7","Tissue RNA - skin 1 [nTPM]":"82.1","Tissue RNA - small intestine [nTPM]":"14.3","Tissue RNA - smooth muscle [nTPM]":"16.9","Tissue RNA - spinal cord [nTPM]":"8.2","Tissue RNA - spleen [nTPM]":"15.0","Tissue RNA - stomach 1 [nTPM]":"11.6","Tissue RNA - testis [nTPM]":"3.8","Tissue RNA - thalamus [nTPM]":"15.8","Tissue RNA - thymus [nTPM]":"34.1","Tissue RNA - thyroid gland [nTPM]":"32.3","Tissue RNA - tongue [nTPM]":"25.1","Tissue RNA - tonsil [nTPM]":"10.4","Tissue RNA - urinary bladder [nTPM]":"26.3","Tissue RNA - vagina [nTPM]":"55.1","Tissue RNA - white matter [nTPM]":"10.0","Cell RNA - A-431 [nTPM]":"13.0","Cell RNA - A549 [nTPM]":"8.1","Cell RNA - AF22 [nTPM]":"66.3","Cell RNA - AN3-CA [nTPM]":"30.3","Cell RNA - ASC diff [nTPM]":"9.2","Cell RNA - ASC TERT1 [nTPM]":"7.3","Cell RNA - BEWO [nTPM]":"29.8","Cell RNA - BJ [nTPM]":"10.2","Cell RNA - BJ hTERT+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"15.6","Cell RNA - CAPAN-2 [nTPM]":"13.4","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"7.7","Cell RNA - fHDF\/TERT166 [nTPM]":"18.9","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"15.1","Cell RNA - HAP1 [nTPM]":"12.1","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.6","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"3.1","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"12.4","Cell RNA - Hep G2 [nTPM]":"3.5","Cell RNA - HHSteC [nTPM]":"4.5","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.2","Cell RNA - HSkMC [nTPM]":"8.4","Cell RNA - hTCEpi [nTPM]":"7.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.5","Cell RNA - hTERT-HME1 [nTPM]":"1.6","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.8","Cell RNA - JURKAT [nTPM]":"4.6","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"0.6","Cell RNA - LHCN-M2 [nTPM]":"1.2","Cell RNA - MCF7 [nTPM]":"66.9","Cell RNA - MOLT-4 [nTPM]":"15.9","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"38.8","Cell RNA - OE19 [nTPM]":"11.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"3.7","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"41.2","Cell RNA - SCLC-21H [nTPM]":"1.9","Cell RNA - SH-SY5Y [nTPM]":"21.4","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"37.8","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"19.6","Cell RNA - T-47d [nTPM]":"40.3","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"1.9","Cell RNA - U-2 OS [nTPM]":"21.0","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.7","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"45.7","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"1.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"14.8","Brain RNA - basal ganglia [nTPM]":"12.4","Brain RNA - cerebellum [nTPM]":"11.0","Brain RNA - cerebral cortex [nTPM]":"21.3","Brain RNA - hippocampal formation [nTPM]":"9.5","Brain RNA - hypothalamus [nTPM]":"11.3","Brain RNA - medulla oblongata [nTPM]":"12.0","Brain RNA - midbrain [nTPM]":"15.2","Brain RNA - pons [nTPM]":"14.3","Brain RNA - spinal cord [nTPM]":"8.2","Brain RNA - thalamus [nTPM]":"15.8","Brain RNA - white matter [nTPM]":"10.0","Single Cell Type RNA - Adipocytes [nTPM]":"39.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.5","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"41.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"60.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"28.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.2","Single Cell Type RNA - dendritic cells [nTPM]":"1.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"14.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.5","Single Cell Type RNA - Endothelial cells [nTPM]":"32.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.9","Single Cell Type RNA - Fibroblasts [nTPM]":"24.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"5.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"10.4","Single Cell Type RNA - Langerhans cells [nTPM]":"12.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"9.0","Single Cell Type RNA - Macrophages [nTPM]":"4.1","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"11.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"414.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"131.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"317.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.9","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"72.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"72.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.5","Single Cell Type RNA - T-cells [nTPM]":"2.0","Single Cell Type RNA - Theca cells [nTPM]":"1.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"36.0"},{"Gene":"OSMR","Gene synonym":["OSMRB","OSMRbeta"],"Ensembl":"ENSG00000145623","Gene description":"Oncostatin M receptor","Uniprot":["Q99650"],"Chromosome":"5","Position":"38845858-38945596","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Amyloidosis","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"74.9","Pancreatic endocrine cells":"72.4","Prostatic glandular cells":"73.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC TERT1":"154.3","GAMG":"162.7","HSkMC":"192.7","U-2197":"158.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA017278"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"51000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA017278":"AB_1854818"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.87e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.96e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-2"},"Tissue RNA - adipose tissue [nTPM]":"59.3","Tissue RNA - adrenal gland [nTPM]":"29.8","Tissue RNA - amygdala [nTPM]":"7.8","Tissue RNA - appendix [nTPM]":"25.3","Tissue RNA - basal ganglia [nTPM]":"7.6","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"37.3","Tissue RNA - cerebellum [nTPM]":"7.4","Tissue RNA - cerebral cortex [nTPM]":"8.4","Tissue RNA - cervix [nTPM]":"26.0","Tissue RNA - choroid plexus [nTPM]":"9.7","Tissue RNA - colon [nTPM]":"25.2","Tissue RNA - duodenum [nTPM]":"5.5","Tissue RNA - endometrium 1 [nTPM]":"22.9","Tissue RNA - epididymis [nTPM]":"7.6","Tissue RNA - esophagus [nTPM]":"17.1","Tissue RNA - fallopian tube [nTPM]":"27.8","Tissue RNA - gallbladder [nTPM]":"28.8","Tissue RNA - heart muscle [nTPM]":"27.6","Tissue RNA - hippocampal formation [nTPM]":"6.5","Tissue RNA - hypothalamus [nTPM]":"10.5","Tissue RNA - kidney [nTPM]":"29.9","Tissue RNA - liver [nTPM]":"19.2","Tissue RNA - lung [nTPM]":"46.2","Tissue RNA - lymph node [nTPM]":"16.0","Tissue RNA - medulla oblongata [nTPM]":"13.4","Tissue RNA - midbrain [nTPM]":"10.8","Tissue RNA - ovary [nTPM]":"24.6","Tissue RNA - pancreas [nTPM]":"16.4","Tissue RNA - parathyroid gland [nTPM]":"6.5","Tissue RNA - pituitary gland [nTPM]":"10.4","Tissue RNA - placenta [nTPM]":"35.3","Tissue RNA - pons [nTPM]":"10.2","Tissue RNA - prostate [nTPM]":"24.6","Tissue RNA - rectum [nTPM]":"10.5","Tissue RNA - retina [nTPM]":"4.3","Tissue RNA - salivary gland [nTPM]":"27.4","Tissue RNA - seminal vesicle [nTPM]":"13.5","Tissue RNA - skeletal muscle [nTPM]":"11.8","Tissue RNA - skin 1 [nTPM]":"21.9","Tissue RNA - small intestine [nTPM]":"15.1","Tissue RNA - smooth muscle [nTPM]":"39.0","Tissue RNA - spinal cord [nTPM]":"9.3","Tissue RNA - spleen [nTPM]":"17.9","Tissue RNA - stomach 1 [nTPM]":"18.4","Tissue RNA - testis [nTPM]":"5.6","Tissue RNA - thalamus [nTPM]":"11.5","Tissue RNA - thymus [nTPM]":"13.9","Tissue RNA - thyroid gland [nTPM]":"23.9","Tissue RNA - tongue [nTPM]":"8.5","Tissue RNA - tonsil [nTPM]":"15.1","Tissue RNA - urinary bladder [nTPM]":"40.9","Tissue RNA - vagina [nTPM]":"22.3","Tissue RNA - white matter [nTPM]":"8.1","Cell RNA - A-431 [nTPM]":"32.6","Cell RNA - A549 [nTPM]":"41.2","Cell RNA - AF22 [nTPM]":"6.9","Cell RNA - AN3-CA [nTPM]":"17.7","Cell RNA - ASC diff [nTPM]":"72.6","Cell RNA - ASC TERT1 [nTPM]":"154.3","Cell RNA - BEWO [nTPM]":"23.4","Cell RNA - BJ [nTPM]":"51.7","Cell RNA - BJ hTERT+ [nTPM]":"81.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"49.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"66.4","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"85.9","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"23.9","Cell RNA - fHDF\/TERT166 [nTPM]":"55.3","Cell RNA - GAMG [nTPM]":"162.7","Cell RNA - HaCaT [nTPM]":"43.9","Cell RNA - HAP1 [nTPM]":"8.9","Cell RNA - HBEC3-KT [nTPM]":"63.6","Cell RNA - HBF TERT88 [nTPM]":"79.8","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"5.1","Cell RNA - HEL [nTPM]":"2.2","Cell RNA - HeLa [nTPM]":"31.2","Cell RNA - Hep G2 [nTPM]":"31.6","Cell RNA - HHSteC [nTPM]":"82.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"192.7","Cell RNA - hTCEpi [nTPM]":"37.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"111.9","Cell RNA - hTERT-HME1 [nTPM]":"94.9","Cell RNA - hTERT-RPE1 [nTPM]":"92.3","Cell RNA - HUVEC TERT2 [nTPM]":"7.7","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"31.8","Cell RNA - MCF7 [nTPM]":"8.8","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"1.1","Cell RNA - OE19 [nTPM]":"6.8","Cell RNA - PC-3 [nTPM]":"13.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"2.3","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"99.8","Cell RNA - RT4 [nTPM]":"9.5","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"116.8","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"9.5","Cell RNA - T-47d [nTPM]":"35.4","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"12.2","Cell RNA - U-138 MG [nTPM]":"120.6","Cell RNA - U-2 OS [nTPM]":"45.1","Cell RNA - U-2197 [nTPM]":"158.1","Cell RNA - U-251 MG [nTPM]":"28.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"96.8","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"26.7","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"7.8","Brain RNA - basal ganglia [nTPM]":"7.6","Brain RNA - cerebellum [nTPM]":"7.4","Brain RNA - cerebral cortex [nTPM]":"8.4","Brain RNA - hippocampal formation [nTPM]":"6.5","Brain RNA - hypothalamus [nTPM]":"10.5","Brain RNA - medulla oblongata [nTPM]":"13.4","Brain RNA - midbrain [nTPM]":"10.8","Brain RNA - pons [nTPM]":"10.2","Brain RNA - spinal cord [nTPM]":"9.3","Brain RNA - thalamus [nTPM]":"11.5","Brain RNA - white matter [nTPM]":"8.1","Single Cell Type RNA - Adipocytes [nTPM]":"41.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"56.8","Single Cell Type RNA - Astrocytes [nTPM]":"13.4","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"74.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"55.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.3","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"51.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.9","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"48.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"38.9","Single Cell Type RNA - Endothelial cells [nTPM]":"47.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"48.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.8","Single Cell Type RNA - Fibroblasts [nTPM]":"37.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.2","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"2.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"55.0","Single Cell Type RNA - Hepatocytes [nTPM]":"16.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"6.1","Single Cell Type RNA - Langerhans cells [nTPM]":"7.6","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"41.7","Single Cell Type RNA - Macrophages [nTPM]":"1.1","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"46.9","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"72.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"73.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"32.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"33.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.1","Single Cell Type RNA - T-cells [nTPM]":"1.7","Single Cell Type RNA - Theca cells [nTPM]":"4.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"57.7"},{"Gene":"PADI3","Gene synonym":["PDI3"],"Ensembl":"ENSG00000142619","Gene description":"Peptidyl arginine deiminase 3","Uniprot":["Q9ULW8"],"Chromosome":"1","Position":"17249098-17284233","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"esophagus":"17.0","urinary bladder":"25.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"1.8","Ionocytes":"6.1","Squamous epithelial cells":"1.1","Urothelial cells":"7.9"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"urothelial cancer":"48.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"14.0","RT4":"17.4","T-47d":"12.8"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043739"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA043739":"AB_10959466"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.32e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.22e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.55e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.73e-3"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"17.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"2.3","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.9","Tissue RNA - seminal vesicle [nTPM]":"3.4","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"3.7","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"25.6","Tissue RNA - vagina [nTPM]":"3.6","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"3.8","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.9","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"14.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"1.4","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"2.6","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"1.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.6","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"2.3","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"17.4","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"2.5","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"12.8","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"3.8","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"7.9"},{"Gene":"PDGFRB","Gene synonym":["CD140b","JTK12","PDGFR","PDGFR1"],"Ensembl":"ENSG00000113721","Gene description":"Platelet derived growth factor receptor beta","Uniprot":["P09619"],"Chromosome":"5","Position":"150113839-150155872","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Chemotaxis"],"Molecular function":["Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Sertoli cells":"1288.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"1.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"ASC diff":"1350.1","ASC TERT1":"462.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003842","CAB018144","HPA028499"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"39000000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB003842":"AB_562328","CAB018144":"AB_2162497","HPA028499":"AB_10602018"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.87e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.11e-4"},"Tissue RNA - adipose tissue [nTPM]":"171.2","Tissue RNA - adrenal gland [nTPM]":"25.1","Tissue RNA - amygdala [nTPM]":"25.4","Tissue RNA - appendix [nTPM]":"27.5","Tissue RNA - basal ganglia [nTPM]":"27.2","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"106.3","Tissue RNA - cerebellum [nTPM]":"20.5","Tissue RNA - cerebral cortex [nTPM]":"33.3","Tissue RNA - cervix [nTPM]":"155.9","Tissue RNA - choroid plexus [nTPM]":"43.5","Tissue RNA - colon [nTPM]":"41.6","Tissue RNA - duodenum [nTPM]":"11.9","Tissue RNA - endometrium 1 [nTPM]":"101.1","Tissue RNA - epididymis [nTPM]":"24.2","Tissue RNA - esophagus [nTPM]":"24.1","Tissue RNA - fallopian tube [nTPM]":"89.6","Tissue RNA - gallbladder [nTPM]":"124.5","Tissue RNA - heart muscle [nTPM]":"75.7","Tissue RNA - hippocampal formation [nTPM]":"22.1","Tissue RNA - hypothalamus [nTPM]":"23.2","Tissue RNA - kidney [nTPM]":"49.7","Tissue RNA - liver [nTPM]":"13.4","Tissue RNA - lung [nTPM]":"98.3","Tissue RNA - lymph node [nTPM]":"27.5","Tissue RNA - medulla oblongata [nTPM]":"22.1","Tissue RNA - midbrain [nTPM]":"24.6","Tissue RNA - ovary [nTPM]":"105.5","Tissue RNA - pancreas [nTPM]":"20.8","Tissue RNA - parathyroid gland [nTPM]":"21.9","Tissue RNA - pituitary gland [nTPM]":"23.0","Tissue RNA - placenta [nTPM]":"113.3","Tissue RNA - pons [nTPM]":"22.8","Tissue RNA - prostate [nTPM]":"56.2","Tissue RNA - rectum [nTPM]":"14.1","Tissue RNA - retina [nTPM]":"6.3","Tissue RNA - salivary gland [nTPM]":"34.5","Tissue RNA - seminal vesicle [nTPM]":"43.3","Tissue RNA - skeletal muscle [nTPM]":"38.1","Tissue RNA - skin 1 [nTPM]":"65.0","Tissue RNA - small intestine [nTPM]":"37.9","Tissue RNA - smooth muscle [nTPM]":"68.9","Tissue RNA - spinal cord [nTPM]":"19.4","Tissue RNA - spleen [nTPM]":"41.4","Tissue RNA - stomach 1 [nTPM]":"27.9","Tissue RNA - testis [nTPM]":"18.4","Tissue RNA - thalamus [nTPM]":"27.7","Tissue RNA - thymus [nTPM]":"8.7","Tissue RNA - thyroid gland [nTPM]":"66.5","Tissue RNA - tongue [nTPM]":"44.1","Tissue RNA - tonsil [nTPM]":"13.8","Tissue RNA - urinary bladder [nTPM]":"58.3","Tissue RNA - vagina [nTPM]":"98.6","Tissue RNA - white matter [nTPM]":"21.6","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"8.3","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"1350.1","Cell RNA - ASC TERT1 [nTPM]":"462.7","Cell RNA - BEWO [nTPM]":"3.0","Cell RNA - BJ [nTPM]":"48.9","Cell RNA - BJ hTERT+ [nTPM]":"202.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"33.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"56.4","Cell RNA - CACO-2 [nTPM]":"5.4","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"6.4","Cell RNA - fHDF\/TERT166 [nTPM]":"142.0","Cell RNA - GAMG [nTPM]":"19.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"15.8","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"3.3","Cell RNA - Hep G2 [nTPM]":"3.5","Cell RNA - HHSteC [nTPM]":"190.7","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"210.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"46.3","Cell RNA - hTERT-HME1 [nTPM]":"0.6","Cell RNA - hTERT-RPE1 [nTPM]":"106.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"5.5","Cell RNA - LHCN-M2 [nTPM]":"5.5","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"9.0","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"3.7","Cell RNA - RH-30 [nTPM]":"2.5","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"24.8","Cell RNA - SiHa [nTPM]":"0.5","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"38.2","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.6","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"53.7","Cell RNA - U-2 OS [nTPM]":"17.2","Cell RNA - U-2197 [nTPM]":"23.1","Cell RNA - U-251 MG [nTPM]":"2.8","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"33.4","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"1.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"1.6","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"25.4","Brain RNA - basal ganglia [nTPM]":"27.2","Brain RNA - cerebellum [nTPM]":"20.5","Brain RNA - cerebral cortex [nTPM]":"33.3","Brain RNA - hippocampal formation [nTPM]":"22.1","Brain RNA - hypothalamus [nTPM]":"23.2","Brain RNA - medulla oblongata [nTPM]":"22.1","Brain RNA - midbrain [nTPM]":"24.6","Brain RNA - pons [nTPM]":"22.8","Brain RNA - spinal cord [nTPM]":"19.4","Brain RNA - thalamus [nTPM]":"27.7","Brain RNA - white matter [nTPM]":"21.6","Single Cell Type RNA - Adipocytes [nTPM]":"50.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"81.9","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"6.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"6.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"99.5","Single Cell Type RNA - Endothelial cells [nTPM]":"32.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.1","Single Cell Type RNA - Fibroblasts [nTPM]":"123.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"1.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"35.6","Single Cell Type RNA - Late spermatids [nTPM]":"10.9","Single Cell Type RNA - Leydig cells [nTPM]":"165.3","Single Cell Type RNA - Macrophages [nTPM]":"3.1","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"45.0","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"50.7","Single Cell Type RNA - NK-cells [nTPM]":"23.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"203.8","Single Cell Type RNA - Plasma cells [nTPM]":"2.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.9","Single Cell Type RNA - Sertoli cells [nTPM]":"1288.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"288.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.9","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"4.8","Single Cell Type RNA - Theca cells [nTPM]":"4.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"1.1"},{"Gene":"PLCD1","Gene synonym":[],"Ensembl":"ENSG00000187091","Gene description":"Phospholipase C delta 1","Uniprot":["P51178"],"Chromosome":"3","Position":"38007496-38029642","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase","Transducer"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"89.5","Theca cells":"53.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"25.3","fHDF\/TERT166":"26.3","hTCEpi":"31.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009913","HPA020107","HPA021677"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Microtubules"],"Subcellular additional location":null,"Antibody RRID":{"CAB009913":"AB_2163388","HPA020107":"AB_1855318","HPA021677":"AB_1855319"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.67e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.25e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.25e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.88e-2"},"Tissue RNA - adipose tissue [nTPM]":"14.8","Tissue RNA - adrenal gland [nTPM]":"12.9","Tissue RNA - amygdala [nTPM]":"14.3","Tissue RNA - appendix [nTPM]":"4.6","Tissue RNA - basal ganglia [nTPM]":"16.1","Tissue RNA - bone marrow [nTPM]":"4.3","Tissue RNA - breast [nTPM]":"10.6","Tissue RNA - cerebellum [nTPM]":"15.4","Tissue RNA - cerebral cortex [nTPM]":"15.6","Tissue RNA - cervix [nTPM]":"15.9","Tissue RNA - choroid plexus [nTPM]":"9.7","Tissue RNA - colon [nTPM]":"15.7","Tissue RNA - duodenum [nTPM]":"4.9","Tissue RNA - endometrium 1 [nTPM]":"11.5","Tissue RNA - epididymis [nTPM]":"4.2","Tissue RNA - esophagus [nTPM]":"26.2","Tissue RNA - fallopian tube [nTPM]":"9.8","Tissue RNA - gallbladder [nTPM]":"5.6","Tissue RNA - heart muscle [nTPM]":"7.2","Tissue RNA - hippocampal formation [nTPM]":"12.8","Tissue RNA - hypothalamus [nTPM]":"19.0","Tissue RNA - kidney [nTPM]":"10.1","Tissue RNA - liver [nTPM]":"5.4","Tissue RNA - lung [nTPM]":"11.3","Tissue RNA - lymph node [nTPM]":"6.6","Tissue RNA - medulla oblongata [nTPM]":"20.3","Tissue RNA - midbrain [nTPM]":"18.5","Tissue RNA - ovary [nTPM]":"12.7","Tissue RNA - pancreas [nTPM]":"6.0","Tissue RNA - parathyroid gland [nTPM]":"3.9","Tissue RNA - pituitary gland [nTPM]":"9.3","Tissue RNA - placenta [nTPM]":"3.8","Tissue RNA - pons [nTPM]":"19.6","Tissue RNA - prostate [nTPM]":"9.1","Tissue RNA - rectum [nTPM]":"10.1","Tissue RNA - retina [nTPM]":"2.8","Tissue RNA - salivary gland [nTPM]":"13.0","Tissue RNA - seminal vesicle [nTPM]":"8.8","Tissue RNA - skeletal muscle [nTPM]":"2.9","Tissue RNA - skin 1 [nTPM]":"18.5","Tissue RNA - small intestine [nTPM]":"8.3","Tissue RNA - smooth muscle [nTPM]":"5.6","Tissue RNA - spinal cord [nTPM]":"19.4","Tissue RNA - spleen [nTPM]":"7.2","Tissue RNA - stomach 1 [nTPM]":"8.3","Tissue RNA - testis [nTPM]":"32.6","Tissue RNA - thalamus [nTPM]":"16.9","Tissue RNA - thymus [nTPM]":"9.1","Tissue RNA - thyroid gland [nTPM]":"8.3","Tissue RNA - tongue [nTPM]":"4.1","Tissue RNA - tonsil [nTPM]":"6.6","Tissue RNA - urinary bladder [nTPM]":"15.7","Tissue RNA - vagina [nTPM]":"19.0","Tissue RNA - white matter [nTPM]":"21.9","Cell RNA - A-431 [nTPM]":"1.0","Cell RNA - A549 [nTPM]":"2.7","Cell RNA - AF22 [nTPM]":"9.4","Cell RNA - AN3-CA [nTPM]":"2.6","Cell RNA - ASC diff [nTPM]":"25.3","Cell RNA - ASC TERT1 [nTPM]":"22.2","Cell RNA - BEWO [nTPM]":"2.8","Cell RNA - BJ [nTPM]":"2.8","Cell RNA - BJ hTERT+ [nTPM]":"11.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.4","Cell RNA - CACO-2 [nTPM]":"1.0","Cell RNA - CAPAN-2 [nTPM]":"2.3","Cell RNA - Daudi [nTPM]":"0.6","Cell RNA - EFO-21 [nTPM]":"1.4","Cell RNA - fHDF\/TERT166 [nTPM]":"26.3","Cell RNA - GAMG [nTPM]":"2.9","Cell RNA - HaCaT [nTPM]":"15.0","Cell RNA - HAP1 [nTPM]":"4.8","Cell RNA - HBEC3-KT [nTPM]":"3.0","Cell RNA - HBF TERT88 [nTPM]":"1.3","Cell RNA - HDLM-2 [nTPM]":"3.9","Cell RNA - HEK 293 [nTPM]":"1.2","Cell RNA - HEL [nTPM]":"0.5","Cell RNA - HeLa [nTPM]":"1.7","Cell RNA - Hep G2 [nTPM]":"4.7","Cell RNA - HHSteC [nTPM]":"14.7","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.6","Cell RNA - HSkMC [nTPM]":"18.0","Cell RNA - hTCEpi [nTPM]":"31.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.9","Cell RNA - hTERT-HME1 [nTPM]":"1.7","Cell RNA - hTERT-RPE1 [nTPM]":"9.4","Cell RNA - HUVEC TERT2 [nTPM]":"8.2","Cell RNA - JURKAT [nTPM]":"2.2","Cell RNA - K-562 [nTPM]":"16.3","Cell RNA - Karpas-707 [nTPM]":"1.3","Cell RNA - LHCN-M2 [nTPM]":"9.6","Cell RNA - MCF7 [nTPM]":"1.2","Cell RNA - MOLT-4 [nTPM]":"2.2","Cell RNA - NB-4 [nTPM]":"1.1","Cell RNA - NTERA-2 [nTPM]":"2.4","Cell RNA - OE19 [nTPM]":"5.5","Cell RNA - PC-3 [nTPM]":"2.7","Cell RNA - REH [nTPM]":"0.9","Cell RNA - RH-30 [nTPM]":"1.3","Cell RNA - RPMI-8226 [nTPM]":"3.6","Cell RNA - RPTEC TERT1 [nTPM]":"5.1","Cell RNA - RT4 [nTPM]":"5.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"2.6","Cell RNA - SiHa [nTPM]":"0.8","Cell RNA - SK-BR-3 [nTPM]":"12.4","Cell RNA - SK-MEL-30 [nTPM]":"3.2","Cell RNA - SuSa [nTPM]":"3.1","Cell RNA - T-47d [nTPM]":"2.7","Cell RNA - THP-1 [nTPM]":"1.2","Cell RNA - TIME [nTPM]":"4.4","Cell RNA - U-138 MG [nTPM]":"2.5","Cell RNA - U-2 OS [nTPM]":"6.3","Cell RNA - U-2197 [nTPM]":"6.7","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"5.2","Cell RNA - U-266\/84 [nTPM]":"2.2","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"6.4","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"1.3","Blood RNA - basophil [nTPM]":"14.6","Blood RNA - classical monocyte [nTPM]":"2.7","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"13.0","Blood RNA - intermediate monocyte [nTPM]":"3.7","Blood RNA - MAIT T-cell [nTPM]":"15.2","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"16.9","Blood RNA - memory CD8 T-cell [nTPM]":"12.8","Blood RNA - myeloid DC [nTPM]":"3.8","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"10.1","Blood RNA - naive CD8 T-cell [nTPM]":"7.9","Blood RNA - neutrophil [nTPM]":"9.9","Blood RNA - NK-cell [nTPM]":"5.9","Blood RNA - non-classical monocyte [nTPM]":"2.2","Blood RNA - plasmacytoid DC [nTPM]":"2.0","Blood RNA - T-reg [nTPM]":"16.6","Blood RNA - total PBMC [nTPM]":"7.4","Brain RNA - amygdala [nTPM]":"14.3","Brain RNA - basal ganglia [nTPM]":"16.1","Brain RNA - cerebellum [nTPM]":"15.4","Brain RNA - cerebral cortex [nTPM]":"15.6","Brain RNA - hippocampal formation [nTPM]":"12.8","Brain RNA - hypothalamus [nTPM]":"19.0","Brain RNA - medulla oblongata [nTPM]":"20.3","Brain RNA - midbrain [nTPM]":"18.5","Brain RNA - pons [nTPM]":"19.6","Brain RNA - spinal cord [nTPM]":"19.4","Brain RNA - thalamus [nTPM]":"16.9","Brain RNA - white matter [nTPM]":"21.9","Single Cell Type RNA - Adipocytes [nTPM]":"5.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.5","Single Cell Type RNA - Astrocytes [nTPM]":"22.9","Single Cell Type RNA - B-cells [nTPM]":"3.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"7.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.8","Single Cell Type RNA - dendritic cells [nTPM]":"4.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"89.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.4","Single Cell Type RNA - Early spermatids [nTPM]":"1.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.3","Single Cell Type RNA - Endothelial cells [nTPM]":"8.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.9","Single Cell Type RNA - Erythroid cells [nTPM]":"3.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.1","Single Cell Type RNA - Fibroblasts [nTPM]":"10.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.8","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"3.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.0","Single Cell Type RNA - Hepatocytes [nTPM]":"4.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.3","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"3.8","Single Cell Type RNA - Langerhans cells [nTPM]":"14.5","Single Cell Type RNA - Late spermatids [nTPM]":"3.6","Single Cell Type RNA - Leydig cells [nTPM]":"12.8","Single Cell Type RNA - Macrophages [nTPM]":"4.3","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"3.4","Single Cell Type RNA - Muller glia cells [nTPM]":"13.3","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.1","Single Cell Type RNA - Paneth cells [nTPM]":"34.7","Single Cell Type RNA - Peritubular cells [nTPM]":"14.3","Single Cell Type RNA - Plasma cells [nTPM]":"5.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.2","Single Cell Type RNA - Spermatocytes [nTPM]":"3.1","Single Cell Type RNA - Spermatogonia [nTPM]":"3.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"7.4","Single Cell Type RNA - Theca cells [nTPM]":"53.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.3","Single Cell Type RNA - Urothelial cells [nTPM]":"14.7"},{"Gene":"POFUT1","Gene synonym":["FUT12","KIAA0180","O-Fuc-T","O-FUT"],"Ensembl":"ENSG00000101346","Gene description":"Protein O-fucosyltransferase 1","Uniprot":["Q9H488"],"Chromosome":"20","Position":"32207880-32238658","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Carbohydrate metabolism","Fucose metabolism","Notch signaling pathway"],"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"39.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"20.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"20.9"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054519","HPA059935"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"60000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"HPA054519":"AB_2682515","HPA059935":"AB_2684171"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.86e-3"},"Tissue RNA - adipose tissue [nTPM]":"17.6","Tissue RNA - adrenal gland [nTPM]":"10.8","Tissue RNA - amygdala [nTPM]":"7.9","Tissue RNA - appendix [nTPM]":"11.7","Tissue RNA - basal ganglia [nTPM]":"8.4","Tissue RNA - bone marrow [nTPM]":"10.5","Tissue RNA - breast [nTPM]":"16.5","Tissue RNA - cerebellum [nTPM]":"7.2","Tissue RNA - cerebral cortex [nTPM]":"7.7","Tissue RNA - cervix [nTPM]":"15.2","Tissue RNA - choroid plexus [nTPM]":"9.1","Tissue RNA - colon [nTPM]":"20.0","Tissue RNA - duodenum [nTPM]":"20.4","Tissue RNA - endometrium 1 [nTPM]":"14.9","Tissue RNA - epididymis [nTPM]":"14.4","Tissue RNA - esophagus [nTPM]":"12.4","Tissue RNA - fallopian tube [nTPM]":"20.4","Tissue RNA - gallbladder [nTPM]":"11.4","Tissue RNA - heart muscle [nTPM]":"17.5","Tissue RNA - hippocampal formation [nTPM]":"7.7","Tissue RNA - hypothalamus [nTPM]":"7.3","Tissue RNA - kidney [nTPM]":"16.1","Tissue RNA - liver [nTPM]":"30.9","Tissue RNA - lung [nTPM]":"12.2","Tissue RNA - lymph node [nTPM]":"9.1","Tissue RNA - medulla oblongata [nTPM]":"9.3","Tissue RNA - midbrain [nTPM]":"8.3","Tissue RNA - ovary [nTPM]":"20.0","Tissue RNA - pancreas [nTPM]":"13.8","Tissue RNA - parathyroid gland [nTPM]":"23.8","Tissue RNA - pituitary gland [nTPM]":"9.1","Tissue RNA - placenta [nTPM]":"16.4","Tissue RNA - pons [nTPM]":"8.0","Tissue RNA - prostate [nTPM]":"14.5","Tissue RNA - rectum [nTPM]":"19.1","Tissue RNA - retina [nTPM]":"5.9","Tissue RNA - salivary gland [nTPM]":"13.0","Tissue RNA - seminal vesicle [nTPM]":"18.1","Tissue RNA - skeletal muscle [nTPM]":"12.8","Tissue RNA - skin 1 [nTPM]":"13.7","Tissue RNA - small intestine [nTPM]":"24.0","Tissue RNA - smooth muscle [nTPM]":"18.1","Tissue RNA - spinal cord [nTPM]":"8.0","Tissue RNA - spleen [nTPM]":"9.4","Tissue RNA - stomach 1 [nTPM]":"11.1","Tissue RNA - testis [nTPM]":"9.5","Tissue RNA - thalamus [nTPM]":"8.1","Tissue RNA - thymus [nTPM]":"10.5","Tissue RNA - thyroid gland [nTPM]":"18.9","Tissue RNA - tongue [nTPM]":"14.0","Tissue RNA - tonsil [nTPM]":"10.0","Tissue RNA - urinary bladder [nTPM]":"14.0","Tissue RNA - vagina [nTPM]":"10.9","Tissue RNA - white matter [nTPM]":"8.2","Cell RNA - A-431 [nTPM]":"47.1","Cell RNA - A549 [nTPM]":"37.2","Cell RNA - AF22 [nTPM]":"31.5","Cell RNA - AN3-CA [nTPM]":"34.7","Cell RNA - ASC diff [nTPM]":"52.9","Cell RNA - ASC TERT1 [nTPM]":"51.4","Cell RNA - BEWO [nTPM]":"58.8","Cell RNA - BJ [nTPM]":"47.8","Cell RNA - BJ hTERT+ [nTPM]":"56.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"78.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"51.3","Cell RNA - CACO-2 [nTPM]":"111.9","Cell RNA - CAPAN-2 [nTPM]":"62.1","Cell RNA - Daudi [nTPM]":"31.7","Cell RNA - EFO-21 [nTPM]":"69.8","Cell RNA - fHDF\/TERT166 [nTPM]":"53.5","Cell RNA - GAMG [nTPM]":"87.2","Cell RNA - HaCaT [nTPM]":"51.2","Cell RNA - HAP1 [nTPM]":"30.5","Cell RNA - HBEC3-KT [nTPM]":"59.0","Cell RNA - HBF TERT88 [nTPM]":"68.0","Cell RNA - HDLM-2 [nTPM]":"16.5","Cell RNA - HEK 293 [nTPM]":"19.2","Cell RNA - HEL [nTPM]":"47.1","Cell RNA - HeLa [nTPM]":"32.1","Cell RNA - Hep G2 [nTPM]":"51.2","Cell RNA - HHSteC [nTPM]":"41.2","Cell RNA - HL-60 [nTPM]":"41.0","Cell RNA - HMC-1 [nTPM]":"28.9","Cell RNA - HSkMC [nTPM]":"45.4","Cell RNA - hTCEpi [nTPM]":"45.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"59.7","Cell RNA - hTERT-HME1 [nTPM]":"38.8","Cell RNA - hTERT-RPE1 [nTPM]":"33.5","Cell RNA - HUVEC TERT2 [nTPM]":"44.6","Cell RNA - JURKAT [nTPM]":"30.0","Cell RNA - K-562 [nTPM]":"36.3","Cell RNA - Karpas-707 [nTPM]":"17.6","Cell RNA - LHCN-M2 [nTPM]":"55.6","Cell RNA - MCF7 [nTPM]":"23.1","Cell RNA - MOLT-4 [nTPM]":"28.4","Cell RNA - NB-4 [nTPM]":"31.4","Cell RNA - NTERA-2 [nTPM]":"16.2","Cell RNA - OE19 [nTPM]":"45.2","Cell RNA - PC-3 [nTPM]":"59.4","Cell RNA - REH [nTPM]":"23.3","Cell RNA - RH-30 [nTPM]":"83.6","Cell RNA - RPMI-8226 [nTPM]":"29.5","Cell RNA - RPTEC TERT1 [nTPM]":"24.2","Cell RNA - RT4 [nTPM]":"30.7","Cell RNA - SCLC-21H [nTPM]":"20.6","Cell RNA - SH-SY5Y [nTPM]":"26.5","Cell RNA - SiHa [nTPM]":"109.5","Cell RNA - SK-BR-3 [nTPM]":"30.0","Cell RNA - SK-MEL-30 [nTPM]":"41.0","Cell RNA - SuSa [nTPM]":"24.0","Cell RNA - T-47d [nTPM]":"44.7","Cell RNA - THP-1 [nTPM]":"48.5","Cell RNA - TIME [nTPM]":"38.8","Cell RNA - U-138 MG [nTPM]":"113.4","Cell RNA - U-2 OS [nTPM]":"42.2","Cell RNA - U-2197 [nTPM]":"71.8","Cell RNA - U-251 MG [nTPM]":"82.4","Cell RNA - U-266\/70 [nTPM]":"21.4","Cell RNA - U-266\/84 [nTPM]":"29.3","Cell RNA - U-698 [nTPM]":"28.7","Cell RNA - U-87 MG [nTPM]":"68.5","Cell RNA - U-937 [nTPM]":"139.9","Cell RNA - WM-115 [nTPM]":"73.0","Blood RNA - basophil [nTPM]":"4.3","Blood RNA - classical monocyte [nTPM]":"5.4","Blood RNA - eosinophil [nTPM]":"2.6","Blood RNA - gdT-cell [nTPM]":"3.2","Blood RNA - intermediate monocyte [nTPM]":"15.1","Blood RNA - MAIT T-cell [nTPM]":"3.6","Blood RNA - memory B-cell [nTPM]":"3.2","Blood RNA - memory CD4 T-cell [nTPM]":"2.8","Blood RNA - memory CD8 T-cell [nTPM]":"3.0","Blood RNA - myeloid DC [nTPM]":"4.6","Blood RNA - naive B-cell [nTPM]":"2.6","Blood RNA - naive CD4 T-cell [nTPM]":"3.6","Blood RNA - naive CD8 T-cell [nTPM]":"2.5","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"2.0","Blood RNA - non-classical monocyte [nTPM]":"20.9","Blood RNA - plasmacytoid DC [nTPM]":"3.4","Blood RNA - T-reg [nTPM]":"3.3","Blood RNA - total PBMC [nTPM]":"4.2","Brain RNA - amygdala [nTPM]":"7.9","Brain RNA - basal ganglia [nTPM]":"8.4","Brain RNA - cerebellum [nTPM]":"7.2","Brain RNA - cerebral cortex [nTPM]":"7.7","Brain RNA - hippocampal formation [nTPM]":"7.7","Brain RNA - hypothalamus [nTPM]":"7.3","Brain RNA - medulla oblongata [nTPM]":"9.3","Brain RNA - midbrain [nTPM]":"8.3","Brain RNA - pons [nTPM]":"8.0","Brain RNA - spinal cord [nTPM]":"8.0","Brain RNA - thalamus [nTPM]":"8.1","Brain RNA - white matter [nTPM]":"8.2","Single Cell Type RNA - Adipocytes [nTPM]":"7.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.5","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"5.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"3.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"7.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.2","Single Cell Type RNA - dendritic cells [nTPM]":"5.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.8","Single Cell Type RNA - Endothelial cells [nTPM]":"9.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.0","Single Cell Type RNA - Erythroid cells [nTPM]":"9.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.2","Single Cell Type RNA - Fibroblasts [nTPM]":"12.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.6","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"13.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.9","Single Cell Type RNA - Hepatocytes [nTPM]":"39.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.7","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.4","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"8.1","Single Cell Type RNA - Langerhans cells [nTPM]":"3.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"10.5","Single Cell Type RNA - Macrophages [nTPM]":"6.5","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"9.3","Single Cell Type RNA - Muller glia cells [nTPM]":"5.2","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.6","Single Cell Type RNA - Paneth cells [nTPM]":"11.9","Single Cell Type RNA - Peritubular cells [nTPM]":"14.3","Single Cell Type RNA - Plasma cells [nTPM]":"8.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"31.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.3","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.4","Single Cell Type RNA - Spermatocytes [nTPM]":"2.9","Single Cell Type RNA - Spermatogonia [nTPM]":"7.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.7","Single Cell Type RNA - T-cells [nTPM]":"5.0","Single Cell Type RNA - Theca cells [nTPM]":"26.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.0","Single Cell Type RNA - Urothelial cells [nTPM]":"4.1"},{"Gene":"PSEN1","Gene synonym":["AD3","FAD","PS1","S182"],"Ensembl":"ENSG00000080815","Gene description":"Presenilin 1","Uniprot":["P49768"],"Chromosome":"14","Position":"73136418-73223691","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis","Cell adhesion","Notch signaling pathway"],"Molecular function":["Hydrolase","Protease"],"Disease involvement":["Alzheimer disease","Amyloidosis","Cancer-related genes","Cardiomyopathy","Disease variant","Neurodegeneration"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Oligodendrocytes":"395.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB006844","HPA030760","HPA067496"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Cell Junctions"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Cell Junctions"],"Antibody RRID":{"CAB006844":null,"HPA030760":"AB_10696211","HPA067496":"AB_2685853"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.48e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.99e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.52e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.12e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Tissue RNA - adipose tissue [nTPM]":"25.1","Tissue RNA - adrenal gland [nTPM]":"22.6","Tissue RNA - amygdala [nTPM]":"44.3","Tissue RNA - appendix [nTPM]":"26.5","Tissue RNA - basal ganglia [nTPM]":"80.7","Tissue RNA - bone marrow [nTPM]":"39.6","Tissue RNA - breast [nTPM]":"28.2","Tissue RNA - cerebellum [nTPM]":"62.4","Tissue RNA - cerebral cortex [nTPM]":"56.0","Tissue RNA - cervix [nTPM]":"28.1","Tissue RNA - choroid plexus [nTPM]":"48.9","Tissue RNA - colon [nTPM]":"49.5","Tissue RNA - duodenum [nTPM]":"50.2","Tissue RNA - endometrium 1 [nTPM]":"25.3","Tissue RNA - epididymis [nTPM]":"26.9","Tissue RNA - esophagus [nTPM]":"35.2","Tissue RNA - fallopian tube [nTPM]":"22.9","Tissue RNA - gallbladder [nTPM]":"31.7","Tissue RNA - heart muscle [nTPM]":"18.0","Tissue RNA - hippocampal formation [nTPM]":"47.4","Tissue RNA - hypothalamus [nTPM]":"51.6","Tissue RNA - kidney [nTPM]":"35.5","Tissue RNA - liver [nTPM]":"31.9","Tissue RNA - lung [nTPM]":"32.1","Tissue RNA - lymph node [nTPM]":"22.4","Tissue RNA - medulla oblongata [nTPM]":"73.0","Tissue RNA - midbrain [nTPM]":"63.8","Tissue RNA - ovary [nTPM]":"22.0","Tissue RNA - pancreas [nTPM]":"22.9","Tissue RNA - parathyroid gland [nTPM]":"35.1","Tissue RNA - pituitary gland [nTPM]":"11.6","Tissue RNA - placenta [nTPM]":"43.1","Tissue RNA - pons [nTPM]":"71.5","Tissue RNA - prostate [nTPM]":"24.3","Tissue RNA - rectum [nTPM]":"46.3","Tissue RNA - retina [nTPM]":"23.4","Tissue RNA - salivary gland [nTPM]":"22.9","Tissue RNA - seminal vesicle [nTPM]":"23.4","Tissue RNA - skeletal muscle [nTPM]":"18.4","Tissue RNA - skin 1 [nTPM]":"38.2","Tissue RNA - small intestine [nTPM]":"49.0","Tissue RNA - smooth muscle [nTPM]":"27.1","Tissue RNA - spinal cord [nTPM]":"55.7","Tissue RNA - spleen [nTPM]":"22.6","Tissue RNA - stomach 1 [nTPM]":"31.0","Tissue RNA - testis [nTPM]":"32.5","Tissue RNA - thalamus [nTPM]":"60.8","Tissue RNA - thymus [nTPM]":"26.2","Tissue RNA - thyroid gland [nTPM]":"36.9","Tissue RNA - tongue [nTPM]":"23.3","Tissue RNA - tonsil [nTPM]":"30.7","Tissue RNA - urinary bladder [nTPM]":"35.0","Tissue RNA - vagina [nTPM]":"19.2","Tissue RNA - white matter [nTPM]":"119.1","Cell RNA - A-431 [nTPM]":"37.1","Cell RNA - A549 [nTPM]":"55.9","Cell RNA - AF22 [nTPM]":"50.6","Cell RNA - AN3-CA [nTPM]":"20.0","Cell RNA - ASC diff [nTPM]":"68.9","Cell RNA - ASC TERT1 [nTPM]":"49.9","Cell RNA - BEWO [nTPM]":"46.7","Cell RNA - BJ [nTPM]":"52.5","Cell RNA - BJ hTERT+ [nTPM]":"60.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"52.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"66.7","Cell RNA - CACO-2 [nTPM]":"69.9","Cell RNA - CAPAN-2 [nTPM]":"88.9","Cell RNA - Daudi [nTPM]":"23.7","Cell RNA - EFO-21 [nTPM]":"34.1","Cell RNA - fHDF\/TERT166 [nTPM]":"50.5","Cell RNA - GAMG [nTPM]":"43.0","Cell RNA - HaCaT [nTPM]":"94.9","Cell RNA - HAP1 [nTPM]":"43.2","Cell RNA - HBEC3-KT [nTPM]":"40.1","Cell RNA - HBF TERT88 [nTPM]":"57.3","Cell RNA - HDLM-2 [nTPM]":"54.6","Cell RNA - HEK 293 [nTPM]":"26.7","Cell RNA - HEL [nTPM]":"27.1","Cell RNA - HeLa [nTPM]":"35.1","Cell RNA - Hep G2 [nTPM]":"34.4","Cell RNA - HHSteC [nTPM]":"63.8","Cell RNA - HL-60 [nTPM]":"27.7","Cell RNA - HMC-1 [nTPM]":"50.7","Cell RNA - HSkMC [nTPM]":"50.4","Cell RNA - hTCEpi [nTPM]":"71.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"44.3","Cell RNA - hTERT-HME1 [nTPM]":"54.4","Cell RNA - hTERT-RPE1 [nTPM]":"48.5","Cell RNA - HUVEC TERT2 [nTPM]":"43.2","Cell RNA - JURKAT [nTPM]":"26.2","Cell RNA - K-562 [nTPM]":"31.0","Cell RNA - Karpas-707 [nTPM]":"46.6","Cell RNA - LHCN-M2 [nTPM]":"50.0","Cell RNA - MCF7 [nTPM]":"72.8","Cell RNA - MOLT-4 [nTPM]":"21.0","Cell RNA - NB-4 [nTPM]":"35.7","Cell RNA - NTERA-2 [nTPM]":"22.0","Cell RNA - OE19 [nTPM]":"64.5","Cell RNA - PC-3 [nTPM]":"40.4","Cell RNA - REH [nTPM]":"26.4","Cell RNA - RH-30 [nTPM]":"42.7","Cell RNA - RPMI-8226 [nTPM]":"30.2","Cell RNA - RPTEC TERT1 [nTPM]":"73.7","Cell RNA - RT4 [nTPM]":"76.5","Cell RNA - SCLC-21H [nTPM]":"28.1","Cell RNA - SH-SY5Y [nTPM]":"38.3","Cell RNA - SiHa [nTPM]":"57.4","Cell RNA - SK-BR-3 [nTPM]":"53.0","Cell RNA - SK-MEL-30 [nTPM]":"47.1","Cell RNA - SuSa [nTPM]":"45.4","Cell RNA - T-47d [nTPM]":"66.3","Cell RNA - THP-1 [nTPM]":"60.7","Cell RNA - TIME [nTPM]":"45.7","Cell RNA - U-138 MG [nTPM]":"53.1","Cell RNA - U-2 OS [nTPM]":"43.5","Cell RNA - U-2197 [nTPM]":"44.1","Cell RNA - U-251 MG [nTPM]":"25.3","Cell RNA - U-266\/70 [nTPM]":"30.3","Cell RNA - U-266\/84 [nTPM]":"47.9","Cell RNA - U-698 [nTPM]":"23.7","Cell RNA - U-87 MG [nTPM]":"44.9","Cell RNA - U-937 [nTPM]":"32.8","Cell RNA - WM-115 [nTPM]":"33.3","Blood RNA - basophil [nTPM]":"126.8","Blood RNA - classical monocyte [nTPM]":"94.5","Blood RNA - eosinophil [nTPM]":"96.3","Blood RNA - gdT-cell [nTPM]":"23.1","Blood RNA - intermediate monocyte [nTPM]":"106.0","Blood RNA - MAIT T-cell [nTPM]":"22.6","Blood RNA - memory B-cell [nTPM]":"23.1","Blood RNA - memory CD4 T-cell [nTPM]":"22.3","Blood RNA - memory CD8 T-cell [nTPM]":"19.0","Blood RNA - myeloid DC [nTPM]":"83.4","Blood RNA - naive B-cell [nTPM]":"31.8","Blood RNA - naive CD4 T-cell [nTPM]":"20.7","Blood RNA - naive CD8 T-cell [nTPM]":"20.1","Blood RNA - neutrophil [nTPM]":"129.3","Blood RNA - NK-cell [nTPM]":"42.8","Blood RNA - non-classical monocyte [nTPM]":"125.0","Blood RNA - plasmacytoid DC [nTPM]":"43.6","Blood RNA - T-reg [nTPM]":"37.0","Blood RNA - total PBMC [nTPM]":"70.3","Brain RNA - amygdala [nTPM]":"44.3","Brain RNA - basal ganglia [nTPM]":"80.7","Brain RNA - cerebellum [nTPM]":"62.4","Brain RNA - cerebral cortex [nTPM]":"56.0","Brain RNA - hippocampal formation [nTPM]":"47.4","Brain RNA - hypothalamus [nTPM]":"51.6","Brain RNA - medulla oblongata [nTPM]":"73.0","Brain RNA - midbrain [nTPM]":"63.8","Brain RNA - pons [nTPM]":"71.5","Brain RNA - spinal cord [nTPM]":"55.7","Brain RNA - thalamus [nTPM]":"60.8","Brain RNA - white matter [nTPM]":"119.1","Single Cell Type RNA - Adipocytes [nTPM]":"22.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.5","Single Cell Type RNA - Astrocytes [nTPM]":"35.9","Single Cell Type RNA - B-cells [nTPM]":"25.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"28.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"24.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Bipolar cells [nTPM]":"17.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"30.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.1","Single Cell Type RNA - dendritic cells [nTPM]":"30.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"79.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"27.1","Single Cell Type RNA - Early spermatids [nTPM]":"22.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.4","Single Cell Type RNA - Endothelial cells [nTPM]":"22.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.2","Single Cell Type RNA - Erythroid cells [nTPM]":"12.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"38.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"29.2","Single Cell Type RNA - Fibroblasts [nTPM]":"23.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"47.4","Single Cell Type RNA - granulocytes [nTPM]":"18.3","Single Cell Type RNA - Granulosa cells [nTPM]":"29.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.7","Single Cell Type RNA - Hepatocytes [nTPM]":"24.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.5","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"40.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.5","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"50.5","Single Cell Type RNA - Langerhans cells [nTPM]":"40.8","Single Cell Type RNA - Late spermatids [nTPM]":"12.9","Single Cell Type RNA - Leydig cells [nTPM]":"16.4","Single Cell Type RNA - Macrophages [nTPM]":"52.3","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"39.4","Single Cell Type RNA - monocytes [nTPM]":"51.8","Single Cell Type RNA - Muller glia cells [nTPM]":"13.8","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"48.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"395.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"38.2","Single Cell Type RNA - Paneth cells [nTPM]":"58.8","Single Cell Type RNA - Peritubular cells [nTPM]":"15.4","Single Cell Type RNA - Plasma cells [nTPM]":"23.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"38.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"76.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"28.0","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.0","Single Cell Type RNA - Spermatocytes [nTPM]":"40.2","Single Cell Type RNA - Spermatogonia [nTPM]":"14.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"33.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"49.9","Single Cell Type RNA - T-cells [nTPM]":"21.6","Single Cell Type RNA - Theca cells [nTPM]":"18.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"41.3","Single Cell Type RNA - Urothelial cells [nTPM]":"51.5"},{"Gene":"PSENEN","Gene synonym":["PEN2"],"Ensembl":"ENSG00000205155","Gene description":"Presenilin enhancer, gamma-secretase subunit","Uniprot":["Q9NZ42"],"Chromosome":"19","Position":"35745600-35747519","Protein class":["Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":["Notch signaling pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"573.3","Respiratory ciliated cells":"954.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047435"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047435":"AB_2680047"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.70e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-3"},"Tissue RNA - adipose tissue [nTPM]":"50.4","Tissue RNA - adrenal gland [nTPM]":"65.7","Tissue RNA - amygdala [nTPM]":"87.8","Tissue RNA - appendix [nTPM]":"39.0","Tissue RNA - basal ganglia [nTPM]":"86.9","Tissue RNA - bone marrow [nTPM]":"35.6","Tissue RNA - breast [nTPM]":"54.2","Tissue RNA - cerebellum [nTPM]":"91.0","Tissue RNA - cerebral cortex [nTPM]":"89.6","Tissue RNA - cervix [nTPM]":"59.4","Tissue RNA - choroid plexus [nTPM]":"127.3","Tissue RNA - colon [nTPM]":"57.3","Tissue RNA - duodenum [nTPM]":"42.0","Tissue RNA - endometrium 1 [nTPM]":"46.5","Tissue RNA - epididymis [nTPM]":"134.6","Tissue RNA - esophagus [nTPM]":"69.5","Tissue RNA - fallopian tube [nTPM]":"228.0","Tissue RNA - gallbladder [nTPM]":"37.8","Tissue RNA - heart muscle [nTPM]":"55.2","Tissue RNA - hippocampal formation [nTPM]":"88.5","Tissue RNA - hypothalamus [nTPM]":"96.1","Tissue RNA - kidney [nTPM]":"76.5","Tissue RNA - liver [nTPM]":"78.4","Tissue RNA - lung [nTPM]":"54.9","Tissue RNA - lymph node [nTPM]":"41.2","Tissue RNA - medulla oblongata [nTPM]":"95.5","Tissue RNA - midbrain [nTPM]":"103.8","Tissue RNA - ovary [nTPM]":"37.5","Tissue RNA - pancreas [nTPM]":"63.0","Tissue RNA - parathyroid gland [nTPM]":"75.1","Tissue RNA - pituitary gland [nTPM]":"60.0","Tissue RNA - placenta [nTPM]":"36.4","Tissue RNA - pons [nTPM]":"100.2","Tissue RNA - prostate [nTPM]":"46.7","Tissue RNA - rectum [nTPM]":"63.4","Tissue RNA - retina [nTPM]":"38.5","Tissue RNA - salivary gland [nTPM]":"55.6","Tissue RNA - seminal vesicle [nTPM]":"53.3","Tissue RNA - skeletal muscle [nTPM]":"51.9","Tissue RNA - skin 1 [nTPM]":"45.4","Tissue RNA - small intestine [nTPM]":"43.1","Tissue RNA - smooth muscle [nTPM]":"47.7","Tissue RNA - spinal cord [nTPM]":"96.0","Tissue RNA - spleen [nTPM]":"57.6","Tissue RNA - stomach 1 [nTPM]":"52.2","Tissue RNA - testis [nTPM]":"148.9","Tissue RNA - thalamus [nTPM]":"89.3","Tissue RNA - thymus [nTPM]":"54.0","Tissue RNA - thyroid gland [nTPM]":"58.4","Tissue RNA - tongue [nTPM]":"46.7","Tissue RNA - tonsil [nTPM]":"61.7","Tissue RNA - urinary bladder [nTPM]":"59.3","Tissue RNA - vagina [nTPM]":"44.6","Tissue RNA - white matter [nTPM]":"97.5","Cell RNA - A-431 [nTPM]":"94.2","Cell RNA - A549 [nTPM]":"187.8","Cell RNA - AF22 [nTPM]":"75.1","Cell RNA - AN3-CA [nTPM]":"87.2","Cell RNA - ASC diff [nTPM]":"136.5","Cell RNA - ASC TERT1 [nTPM]":"85.3","Cell RNA - BEWO [nTPM]":"43.2","Cell RNA - BJ [nTPM]":"49.8","Cell RNA - BJ hTERT+ [nTPM]":"108.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"111.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"117.7","Cell RNA - CACO-2 [nTPM]":"52.3","Cell RNA - CAPAN-2 [nTPM]":"173.7","Cell RNA - Daudi [nTPM]":"48.9","Cell RNA - EFO-21 [nTPM]":"116.0","Cell RNA - fHDF\/TERT166 [nTPM]":"99.4","Cell RNA - GAMG [nTPM]":"76.2","Cell RNA - HaCaT [nTPM]":"54.6","Cell RNA - HAP1 [nTPM]":"65.3","Cell RNA - HBEC3-KT [nTPM]":"86.1","Cell RNA - HBF TERT88 [nTPM]":"105.0","Cell RNA - HDLM-2 [nTPM]":"81.8","Cell RNA - HEK 293 [nTPM]":"55.1","Cell RNA - HEL [nTPM]":"34.5","Cell RNA - HeLa [nTPM]":"44.1","Cell RNA - Hep G2 [nTPM]":"50.6","Cell RNA - HHSteC [nTPM]":"118.9","Cell RNA - HL-60 [nTPM]":"53.7","Cell RNA - HMC-1 [nTPM]":"60.5","Cell RNA - HSkMC [nTPM]":"88.8","Cell RNA - hTCEpi [nTPM]":"153.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"129.7","Cell RNA - hTERT-HME1 [nTPM]":"106.2","Cell RNA - hTERT-RPE1 [nTPM]":"95.8","Cell RNA - HUVEC TERT2 [nTPM]":"112.2","Cell RNA - JURKAT [nTPM]":"94.1","Cell RNA - K-562 [nTPM]":"53.7","Cell RNA - Karpas-707 [nTPM]":"116.5","Cell RNA - LHCN-M2 [nTPM]":"127.8","Cell RNA - MCF7 [nTPM]":"108.5","Cell RNA - MOLT-4 [nTPM]":"62.8","Cell RNA - NB-4 [nTPM]":"63.7","Cell RNA - NTERA-2 [nTPM]":"55.9","Cell RNA - OE19 [nTPM]":"214.9","Cell RNA - PC-3 [nTPM]":"49.7","Cell RNA - REH [nTPM]":"58.8","Cell RNA - RH-30 [nTPM]":"30.2","Cell RNA - RPMI-8226 [nTPM]":"89.9","Cell RNA - RPTEC TERT1 [nTPM]":"226.4","Cell RNA - RT4 [nTPM]":"46.7","Cell RNA - SCLC-21H [nTPM]":"62.1","Cell RNA - SH-SY5Y [nTPM]":"94.5","Cell RNA - SiHa [nTPM]":"65.6","Cell RNA - SK-BR-3 [nTPM]":"144.3","Cell RNA - SK-MEL-30 [nTPM]":"45.6","Cell RNA - SuSa [nTPM]":"98.8","Cell RNA - T-47d [nTPM]":"92.0","Cell RNA - THP-1 [nTPM]":"119.7","Cell RNA - TIME [nTPM]":"46.4","Cell RNA - U-138 MG [nTPM]":"88.4","Cell RNA - U-2 OS [nTPM]":"52.9","Cell RNA - U-2197 [nTPM]":"60.3","Cell RNA - U-251 MG [nTPM]":"81.1","Cell RNA - U-266\/70 [nTPM]":"88.0","Cell RNA - U-266\/84 [nTPM]":"107.6","Cell RNA - U-698 [nTPM]":"62.1","Cell RNA - U-87 MG [nTPM]":"152.0","Cell RNA - U-937 [nTPM]":"50.3","Cell RNA - WM-115 [nTPM]":"72.1","Blood RNA - basophil [nTPM]":"140.8","Blood RNA - classical monocyte [nTPM]":"208.3","Blood RNA - eosinophil [nTPM]":"202.0","Blood RNA - gdT-cell [nTPM]":"131.3","Blood RNA - intermediate monocyte [nTPM]":"232.9","Blood RNA - MAIT T-cell [nTPM]":"123.9","Blood RNA - memory B-cell [nTPM]":"109.3","Blood RNA - memory CD4 T-cell [nTPM]":"95.8","Blood RNA - memory CD8 T-cell [nTPM]":"114.0","Blood RNA - myeloid DC [nTPM]":"154.8","Blood RNA - naive B-cell [nTPM]":"100.4","Blood RNA - naive CD4 T-cell [nTPM]":"73.1","Blood RNA - naive CD8 T-cell [nTPM]":"92.9","Blood RNA - neutrophil [nTPM]":"539.2","Blood RNA - NK-cell [nTPM]":"91.4","Blood RNA - non-classical monocyte [nTPM]":"191.1","Blood RNA - plasmacytoid DC [nTPM]":"337.1","Blood RNA - T-reg [nTPM]":"107.4","Blood RNA - total PBMC [nTPM]":"245.3","Brain RNA - amygdala [nTPM]":"87.8","Brain RNA - basal ganglia [nTPM]":"86.9","Brain RNA - cerebellum [nTPM]":"91.0","Brain RNA - cerebral cortex [nTPM]":"89.6","Brain RNA - hippocampal formation [nTPM]":"88.5","Brain RNA - hypothalamus [nTPM]":"96.1","Brain RNA - medulla oblongata [nTPM]":"95.5","Brain RNA - midbrain [nTPM]":"103.8","Brain RNA - pons [nTPM]":"100.2","Brain RNA - spinal cord [nTPM]":"96.0","Brain RNA - thalamus [nTPM]":"89.3","Brain RNA - white matter [nTPM]":"97.5","Single Cell Type RNA - Adipocytes [nTPM]":"58.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"38.2","Single Cell Type RNA - Astrocytes [nTPM]":"4.2","Single Cell Type RNA - B-cells [nTPM]":"53.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"38.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"59.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"192.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"39.3","Single Cell Type RNA - Bipolar cells [nTPM]":"13.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"55.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"36.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"29.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"51.5","Single Cell Type RNA - Club cells [nTPM]":"137.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"128.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"92.5","Single Cell Type RNA - dendritic cells [nTPM]":"73.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"132.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"60.7","Single Cell Type RNA - Ductal cells [nTPM]":"146.8","Single Cell Type RNA - Early spermatids [nTPM]":"199.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"573.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"42.7","Single Cell Type RNA - Endothelial cells [nTPM]":"52.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"70.2","Single Cell Type RNA - Erythroid cells [nTPM]":"36.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"151.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"135.9","Single Cell Type RNA - Fibroblasts [nTPM]":"50.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"34.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"75.6","Single Cell Type RNA - granulocytes [nTPM]":"57.7","Single Cell Type RNA - Granulosa cells [nTPM]":"22.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"42.1","Single Cell Type RNA - Hepatocytes [nTPM]":"49.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"164.4","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"66.1","Single Cell Type RNA - Ionocytes [nTPM]":"185.1","Single Cell Type RNA - Kupffer cells [nTPM]":"51.2","Single Cell Type RNA - Langerhans cells [nTPM]":"90.9","Single Cell Type RNA - Late spermatids [nTPM]":"126.5","Single Cell Type RNA - Leydig cells [nTPM]":"54.7","Single Cell Type RNA - Macrophages [nTPM]":"69.8","Single Cell Type RNA - Melanocytes [nTPM]":"71.2","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"85.9","Single Cell Type RNA - Muller glia cells [nTPM]":"58.6","Single Cell Type RNA - NK-cells [nTPM]":"86.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"171.4","Single Cell Type RNA - Paneth cells [nTPM]":"152.5","Single Cell Type RNA - Peritubular cells [nTPM]":"40.6","Single Cell Type RNA - Plasma cells [nTPM]":"83.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"44.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"122.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"194.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"954.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.7","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"33.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"147.7","Single Cell Type RNA - Spermatocytes [nTPM]":"344.8","Single Cell Type RNA - Spermatogonia [nTPM]":"35.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"48.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"48.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"104.1","Single Cell Type RNA - T-cells [nTPM]":"53.3","Single Cell Type RNA - Theca cells [nTPM]":"56.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"67.3","Single Cell Type RNA - Urothelial cells [nTPM]":"74.0"},{"Gene":"PTCH1","Gene synonym":["BCNS","NBCCS","PTCH"],"Ensembl":"ENSG00000185920","Gene description":"Patched 1","Uniprot":["Q13635"],"Chromosome":"9","Position":"95442980-95517057","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","Holoprosencephaly","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"26.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"237.5","Leydig cells":"191.0","Peritubular cells":"444.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"6.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"T-cells":"6.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NTERA-2":"29.6","WM-115":"71.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013717","HPA075072"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB013717":null,"HPA075072":"AB_2686733"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.0","Tissue RNA - adrenal gland [nTPM]":"3.5","Tissue RNA - amygdala [nTPM]":"9.5","Tissue RNA - appendix [nTPM]":"4.0","Tissue RNA - basal ganglia [nTPM]":"11.6","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"2.8","Tissue RNA - cerebellum [nTPM]":"24.6","Tissue RNA - cerebral cortex [nTPM]":"5.6","Tissue RNA - cervix [nTPM]":"26.7","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"11.3","Tissue RNA - duodenum [nTPM]":"8.1","Tissue RNA - endometrium 1 [nTPM]":"15.6","Tissue RNA - epididymis [nTPM]":"2.7","Tissue RNA - esophagus [nTPM]":"2.9","Tissue RNA - fallopian tube [nTPM]":"7.1","Tissue RNA - gallbladder [nTPM]":"8.1","Tissue RNA - heart muscle [nTPM]":"2.9","Tissue RNA - hippocampal formation [nTPM]":"4.7","Tissue RNA - hypothalamus [nTPM]":"17.8","Tissue RNA - kidney [nTPM]":"4.6","Tissue RNA - liver [nTPM]":"2.2","Tissue RNA - lung [nTPM]":"5.5","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"16.0","Tissue RNA - midbrain [nTPM]":"12.7","Tissue RNA - ovary [nTPM]":"5.0","Tissue RNA - pancreas [nTPM]":"6.4","Tissue RNA - parathyroid gland [nTPM]":"2.5","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"3.8","Tissue RNA - pons [nTPM]":"8.0","Tissue RNA - prostate [nTPM]":"6.8","Tissue RNA - rectum [nTPM]":"12.3","Tissue RNA - retina [nTPM]":"8.3","Tissue RNA - salivary gland [nTPM]":"7.5","Tissue RNA - seminal vesicle [nTPM]":"4.0","Tissue RNA - skeletal muscle [nTPM]":"3.0","Tissue RNA - skin 1 [nTPM]":"3.2","Tissue RNA - small intestine [nTPM]":"11.6","Tissue RNA - smooth muscle [nTPM]":"2.4","Tissue RNA - spinal cord [nTPM]":"7.0","Tissue RNA - spleen [nTPM]":"3.3","Tissue RNA - stomach 1 [nTPM]":"12.5","Tissue RNA - testis [nTPM]":"14.5","Tissue RNA - thalamus [nTPM]":"24.0","Tissue RNA - thymus [nTPM]":"2.1","Tissue RNA - thyroid gland [nTPM]":"4.7","Tissue RNA - tongue [nTPM]":"4.8","Tissue RNA - tonsil [nTPM]":"3.0","Tissue RNA - urinary bladder [nTPM]":"7.2","Tissue RNA - vagina [nTPM]":"2.9","Tissue RNA - white matter [nTPM]":"4.5","Cell RNA - A-431 [nTPM]":"10.1","Cell RNA - A549 [nTPM]":"4.7","Cell RNA - AF22 [nTPM]":"20.3","Cell RNA - AN3-CA [nTPM]":"12.9","Cell RNA - ASC diff [nTPM]":"3.0","Cell RNA - ASC TERT1 [nTPM]":"5.0","Cell RNA - BEWO [nTPM]":"11.4","Cell RNA - BJ [nTPM]":"1.9","Cell RNA - BJ hTERT+ [nTPM]":"1.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.4","Cell RNA - CACO-2 [nTPM]":"4.9","Cell RNA - CAPAN-2 [nTPM]":"4.8","Cell RNA - Daudi [nTPM]":"8.0","Cell RNA - EFO-21 [nTPM]":"3.3","Cell RNA - fHDF\/TERT166 [nTPM]":"3.8","Cell RNA - GAMG [nTPM]":"4.4","Cell RNA - HaCaT [nTPM]":"22.3","Cell RNA - HAP1 [nTPM]":"11.7","Cell RNA - HBEC3-KT [nTPM]":"1.6","Cell RNA - HBF TERT88 [nTPM]":"1.4","Cell RNA - HDLM-2 [nTPM]":"7.9","Cell RNA - HEK 293 [nTPM]":"7.8","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"4.8","Cell RNA - Hep G2 [nTPM]":"2.3","Cell RNA - HHSteC [nTPM]":"2.7","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"4.2","Cell RNA - HSkMC [nTPM]":"4.7","Cell RNA - hTCEpi [nTPM]":"2.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.2","Cell RNA - hTERT-HME1 [nTPM]":"1.4","Cell RNA - hTERT-RPE1 [nTPM]":"4.3","Cell RNA - HUVEC TERT2 [nTPM]":"4.2","Cell RNA - JURKAT [nTPM]":"3.5","Cell RNA - K-562 [nTPM]":"7.3","Cell RNA - Karpas-707 [nTPM]":"9.1","Cell RNA - LHCN-M2 [nTPM]":"1.0","Cell RNA - MCF7 [nTPM]":"1.9","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"3.2","Cell RNA - NTERA-2 [nTPM]":"29.6","Cell RNA - OE19 [nTPM]":"7.2","Cell RNA - PC-3 [nTPM]":"1.8","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"15.5","Cell RNA - RPMI-8226 [nTPM]":"4.2","Cell RNA - RPTEC TERT1 [nTPM]":"1.6","Cell RNA - RT4 [nTPM]":"1.5","Cell RNA - SCLC-21H [nTPM]":"13.8","Cell RNA - SH-SY5Y [nTPM]":"7.0","Cell RNA - SiHa [nTPM]":"7.1","Cell RNA - SK-BR-3 [nTPM]":"6.8","Cell RNA - SK-MEL-30 [nTPM]":"2.9","Cell RNA - SuSa [nTPM]":"18.8","Cell RNA - T-47d [nTPM]":"1.8","Cell RNA - THP-1 [nTPM]":"2.1","Cell RNA - TIME [nTPM]":"1.1","Cell RNA - U-138 MG [nTPM]":"2.6","Cell RNA - U-2 OS [nTPM]":"12.9","Cell RNA - U-2197 [nTPM]":"13.6","Cell RNA - U-251 MG [nTPM]":"1.5","Cell RNA - U-266\/70 [nTPM]":"18.0","Cell RNA - U-266\/84 [nTPM]":"16.8","Cell RNA - U-698 [nTPM]":"5.3","Cell RNA - U-87 MG [nTPM]":"3.8","Cell RNA - U-937 [nTPM]":"3.9","Cell RNA - WM-115 [nTPM]":"71.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"6.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"3.3","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"2.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"9.5","Brain RNA - basal ganglia [nTPM]":"11.6","Brain RNA - cerebellum [nTPM]":"24.6","Brain RNA - cerebral cortex [nTPM]":"5.6","Brain RNA - hippocampal formation [nTPM]":"4.7","Brain RNA - hypothalamus [nTPM]":"17.8","Brain RNA - medulla oblongata [nTPM]":"16.0","Brain RNA - midbrain [nTPM]":"12.7","Brain RNA - pons [nTPM]":"8.0","Brain RNA - spinal cord [nTPM]":"7.0","Brain RNA - thalamus [nTPM]":"24.0","Brain RNA - white matter [nTPM]":"4.5","Single Cell Type RNA - Adipocytes [nTPM]":"6.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.4","Single Cell Type RNA - Astrocytes [nTPM]":"49.0","Single Cell Type RNA - B-cells [nTPM]":"3.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"20.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"2.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - dendritic cells [nTPM]":"11.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.5","Single Cell Type RNA - Early spermatids [nTPM]":"88.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"89.8","Single Cell Type RNA - Endothelial cells [nTPM]":"5.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.7","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.9","Single Cell Type RNA - Fibroblasts [nTPM]":"27.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"2.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"2.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.8","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.9","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"237.5","Single Cell Type RNA - Leydig cells [nTPM]":"191.0","Single Cell Type RNA - Macrophages [nTPM]":"1.4","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.8","Single Cell Type RNA - Muller glia cells [nTPM]":"55.6","Single Cell Type RNA - NK-cells [nTPM]":"54.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"39.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.4","Single Cell Type RNA - Paneth cells [nTPM]":"3.1","Single Cell Type RNA - Peritubular cells [nTPM]":"444.5","Single Cell Type RNA - Plasma cells [nTPM]":"3.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.4","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.4","Single Cell Type RNA - Spermatocytes [nTPM]":"4.4","Single Cell Type RNA - Spermatogonia [nTPM]":"35.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"6.5","Single Cell Type RNA - Theca cells [nTPM]":"71.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.7","Single Cell Type RNA - Urothelial cells [nTPM]":"1.4"},{"Gene":"PTCH2","Gene synonym":[],"Ensembl":"ENSG00000117425","Gene description":"Patched 2","Uniprot":["Q9Y6C5"],"Chromosome":"1","Position":"44819844-44843253","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"ovary":"24.6","parathyroid gland":"59.1","salivary gland":"75.2","testis":"25.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Leydig cells":"107.8","Peritubular cells":"68.1","Plasma cells":"67.1","Theca cells":"138.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"9.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-266\/84":"11.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046839"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA046839":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.74e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.81e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.2","Tissue RNA - adrenal gland [nTPM]":"3.1","Tissue RNA - amygdala [nTPM]":"6.1","Tissue RNA - appendix [nTPM]":"0.8","Tissue RNA - basal ganglia [nTPM]":"3.5","Tissue RNA - bone marrow [nTPM]":"9.4","Tissue RNA - breast [nTPM]":"3.4","Tissue RNA - cerebellum [nTPM]":"6.8","Tissue RNA - cerebral cortex [nTPM]":"6.8","Tissue RNA - cervix [nTPM]":"5.1","Tissue RNA - choroid plexus [nTPM]":"3.6","Tissue RNA - colon [nTPM]":"3.6","Tissue RNA - duodenum [nTPM]":"1.0","Tissue RNA - endometrium 1 [nTPM]":"6.4","Tissue RNA - epididymis [nTPM]":"1.6","Tissue RNA - esophagus [nTPM]":"0.9","Tissue RNA - fallopian tube [nTPM]":"4.3","Tissue RNA - gallbladder [nTPM]":"2.5","Tissue RNA - heart muscle [nTPM]":"1.3","Tissue RNA - hippocampal formation [nTPM]":"3.1","Tissue RNA - hypothalamus [nTPM]":"4.4","Tissue RNA - kidney [nTPM]":"1.3","Tissue RNA - liver [nTPM]":"1.3","Tissue RNA - lung [nTPM]":"1.0","Tissue RNA - lymph node [nTPM]":"2.3","Tissue RNA - medulla oblongata [nTPM]":"2.9","Tissue RNA - midbrain [nTPM]":"4.8","Tissue RNA - ovary [nTPM]":"24.6","Tissue RNA - pancreas [nTPM]":"1.0","Tissue RNA - parathyroid gland [nTPM]":"59.1","Tissue RNA - pituitary gland [nTPM]":"9.9","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"2.0","Tissue RNA - prostate [nTPM]":"3.0","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"3.6","Tissue RNA - salivary gland [nTPM]":"75.2","Tissue RNA - seminal vesicle [nTPM]":"1.3","Tissue RNA - skeletal muscle [nTPM]":"2.0","Tissue RNA - skin 1 [nTPM]":"3.6","Tissue RNA - small intestine [nTPM]":"1.8","Tissue RNA - smooth muscle [nTPM]":"1.2","Tissue RNA - spinal cord [nTPM]":"1.6","Tissue RNA - spleen [nTPM]":"2.4","Tissue RNA - stomach 1 [nTPM]":"2.0","Tissue RNA - testis [nTPM]":"25.6","Tissue RNA - thalamus [nTPM]":"6.5","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"4.6","Tissue RNA - tongue [nTPM]":"0.8","Tissue RNA - tonsil [nTPM]":"0.7","Tissue RNA - urinary bladder [nTPM]":"3.1","Tissue RNA - vagina [nTPM]":"3.4","Tissue RNA - white matter [nTPM]":"4.8","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"1.0","Cell RNA - AN3-CA [nTPM]":"2.5","Cell RNA - ASC diff [nTPM]":"0.8","Cell RNA - ASC TERT1 [nTPM]":"0.9","Cell RNA - BEWO [nTPM]":"1.0","Cell RNA - BJ [nTPM]":"0.8","Cell RNA - BJ hTERT+ [nTPM]":"1.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"1.1","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.2","Cell RNA - HDLM-2 [nTPM]":"2.1","Cell RNA - HEK 293 [nTPM]":"1.9","Cell RNA - HEL [nTPM]":"0.6","Cell RNA - HeLa [nTPM]":"1.0","Cell RNA - Hep G2 [nTPM]":"0.8","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"1.1","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"1.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"1.0","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"1.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"1.4","Cell RNA - NB-4 [nTPM]":"2.1","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"1.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.5","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"1.2","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"1.3","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"1.9","Cell RNA - U-266\/84 [nTPM]":"11.6","Cell RNA - U-698 [nTPM]":"3.2","Cell RNA - U-87 MG [nTPM]":"0.6","Cell RNA - U-937 [nTPM]":"3.0","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"2.5","Blood RNA - classical monocyte [nTPM]":"1.9","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"1.2","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"3.6","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"6.1","Brain RNA - basal ganglia [nTPM]":"3.5","Brain RNA - cerebellum [nTPM]":"6.8","Brain RNA - cerebral cortex [nTPM]":"6.8","Brain RNA - hippocampal formation [nTPM]":"3.1","Brain RNA - hypothalamus [nTPM]":"4.4","Brain RNA - medulla oblongata [nTPM]":"2.9","Brain RNA - midbrain [nTPM]":"4.8","Brain RNA - pons [nTPM]":"2.0","Brain RNA - spinal cord [nTPM]":"1.6","Brain RNA - thalamus [nTPM]":"6.5","Brain RNA - white matter [nTPM]":"4.8","Single Cell Type RNA - Adipocytes [nTPM]":"2.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"14.0","Single Cell Type RNA - B-cells [nTPM]":"13.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"1.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.4","Single Cell Type RNA - dendritic cells [nTPM]":"6.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.5","Single Cell Type RNA - Early spermatids [nTPM]":"2.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.5","Single Cell Type RNA - Endothelial cells [nTPM]":"2.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.5","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"23.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.6","Single Cell Type RNA - Fibroblasts [nTPM]":"14.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"4.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"7.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.7","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"27.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.9","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"24.5","Single Cell Type RNA - Langerhans cells [nTPM]":"2.2","Single Cell Type RNA - Late spermatids [nTPM]":"8.0","Single Cell Type RNA - Leydig cells [nTPM]":"107.8","Single Cell Type RNA - Macrophages [nTPM]":"17.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"3.9","Single Cell Type RNA - Muller glia cells [nTPM]":"2.4","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.1","Single Cell Type RNA - Paneth cells [nTPM]":"2.5","Single Cell Type RNA - Peritubular cells [nTPM]":"68.1","Single Cell Type RNA - Plasma cells [nTPM]":"67.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.6","Single Cell Type RNA - Spermatocytes [nTPM]":"5.0","Single Cell Type RNA - Spermatogonia [nTPM]":"3.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.3","Single Cell Type RNA - T-cells [nTPM]":"7.5","Single Cell Type RNA - Theca cells [nTPM]":"138.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.5","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"PTPN22","Gene synonym":["Lyp","Lyp1","Lyp2","PTPN8"],"Ensembl":"ENSG00000134242","Gene description":"Protein tyrosine phosphatase non-receptor type 22","Uniprot":["Q9Y2R2"],"Chromosome":"1","Position":"113813811-113871753","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Autophagy","Immunity"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Diabetes mellitus","Disease variant","Systemic lupus erythematosus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"38.0","lymphoid tissue":"20.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"B-cells":"67.4","dendritic cells":"176.0","NK-cells":"108.1","Plasma cells":"79.6","T-cells":"151.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"69.3","HL-60":"27.7","U-266\/70":"29.2","U-698":"37.5","U-937":"28.4"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"11","RNA mouse brain regional specific nTPM":{"cerebellum":"5.3"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004912","CAB012209","HPA013350"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles","Plasma membrane"],"Antibody RRID":{"CAB012209":null,"HPA004912":"AB_10602069","HPA013350":"AB_10601570"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.0","Tissue RNA - adrenal gland [nTPM]":"1.5","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"11.5","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"38.0","Tissue RNA - breast [nTPM]":"2.3","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"1.8","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"4.0","Tissue RNA - duodenum [nTPM]":"6.4","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"1.1","Tissue RNA - esophagus [nTPM]":"1.7","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"4.8","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"2.0","Tissue RNA - lung [nTPM]":"7.5","Tissue RNA - lymph node [nTPM]":"20.3","Tissue RNA - medulla oblongata [nTPM]":"0.5","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"1.3","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.8","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"1.0","Tissue RNA - rectum [nTPM]":"4.3","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"1.3","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"8.6","Tissue RNA - smooth muscle [nTPM]":"1.6","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"13.2","Tissue RNA - stomach 1 [nTPM]":"5.2","Tissue RNA - testis [nTPM]":"1.4","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"20.0","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"13.5","Tissue RNA - urinary bladder [nTPM]":"4.2","Tissue RNA - vagina [nTPM]":"0.9","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.9","Cell RNA - BJ hTERT+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.7","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"69.3","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.5","Cell RNA - HDLM-2 [nTPM]":"6.5","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"10.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"27.7","Cell RNA - HMC-1 [nTPM]":"21.1","Cell RNA - HSkMC [nTPM]":"5.7","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.8","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"5.1","Cell RNA - HUVEC TERT2 [nTPM]":"10.6","Cell RNA - JURKAT [nTPM]":"17.2","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"15.7","Cell RNA - LHCN-M2 [nTPM]":"10.3","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"20.1","Cell RNA - NB-4 [nTPM]":"15.7","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"1.2","Cell RNA - RH-30 [nTPM]":"6.7","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.5","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"10.0","Cell RNA - TIME [nTPM]":"5.0","Cell RNA - U-138 MG [nTPM]":"16.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"29.2","Cell RNA - U-266\/84 [nTPM]":"6.6","Cell RNA - U-698 [nTPM]":"37.5","Cell RNA - U-87 MG [nTPM]":"11.1","Cell RNA - U-937 [nTPM]":"28.4","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"15.8","Blood RNA - classical monocyte [nTPM]":"4.8","Blood RNA - eosinophil [nTPM]":"25.0","Blood RNA - gdT-cell [nTPM]":"17.0","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"20.1","Blood RNA - memory B-cell [nTPM]":"9.9","Blood RNA - memory CD4 T-cell [nTPM]":"8.4","Blood RNA - memory CD8 T-cell [nTPM]":"13.6","Blood RNA - myeloid DC [nTPM]":"8.7","Blood RNA - naive B-cell [nTPM]":"7.4","Blood RNA - naive CD4 T-cell [nTPM]":"5.0","Blood RNA - naive CD8 T-cell [nTPM]":"12.1","Blood RNA - neutrophil [nTPM]":"2.4","Blood RNA - NK-cell [nTPM]":"11.0","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"5.2","Blood RNA - T-reg [nTPM]":"14.5","Blood RNA - total PBMC [nTPM]":"7.3","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.5","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"2.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"67.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"176.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"1.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"16.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"2.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.0","Single Cell Type RNA - granulocytes [nTPM]":"27.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"17.3","Single Cell Type RNA - Langerhans cells [nTPM]":"26.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"26.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"14.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"108.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"0.8","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"79.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"151.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"RHOH","Gene synonym":["ARHH","TTF"],"Ensembl":"ENSG00000168421","Gene description":"Ras homolog family member H","Uniprot":["Q15669"],"Chromosome":"4","Position":"40191053-40246967","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"62.9","lymphoid tissue":"98.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"273.0","dendritic cells":"90.5","granulocytes":"141.8","NK-cells":"64.9","Plasma cells":"183.1","T-cells":"223.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"4.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"126.3","HMC-1":"92.5","JURKAT":"123.7","MOLT-4":"179.4","U-266\/70":"65.5","U-266\/84":"56.8","U-698":"116.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030345","HPA061314"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Golgi apparatus","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA030345":"AB_10601607","HPA061314":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.2","Tissue RNA - adrenal gland [nTPM]":"0.9","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"36.4","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"62.9","Tissue RNA - breast [nTPM]":"13.2","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"0.8","Tissue RNA - cervix [nTPM]":"2.9","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"6.3","Tissue RNA - duodenum [nTPM]":"4.8","Tissue RNA - endometrium 1 [nTPM]":"1.6","Tissue RNA - epididymis [nTPM]":"0.9","Tissue RNA - esophagus [nTPM]":"2.9","Tissue RNA - fallopian tube [nTPM]":"1.5","Tissue RNA - gallbladder [nTPM]":"6.4","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"0.6","Tissue RNA - hypothalamus [nTPM]":"0.8","Tissue RNA - kidney [nTPM]":"1.2","Tissue RNA - liver [nTPM]":"2.7","Tissue RNA - lung [nTPM]":"5.7","Tissue RNA - lymph node [nTPM]":"86.0","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"1.3","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"1.4","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"0.7","Tissue RNA - placenta [nTPM]":"0.9","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"2.7","Tissue RNA - rectum [nTPM]":"5.6","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"3.9","Tissue RNA - seminal vesicle [nTPM]":"0.9","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"1.2","Tissue RNA - small intestine [nTPM]":"20.6","Tissue RNA - smooth muscle [nTPM]":"1.5","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"42.6","Tissue RNA - stomach 1 [nTPM]":"8.2","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"0.8","Tissue RNA - thymus [nTPM]":"98.2","Tissue RNA - thyroid gland [nTPM]":"1.8","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"85.2","Tissue RNA - urinary bladder [nTPM]":"10.6","Tissue RNA - vagina [nTPM]":"1.6","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"126.3","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"2.6","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"18.8","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"21.1","Cell RNA - HMC-1 [nTPM]":"92.5","Cell RNA - HSkMC [nTPM]":"1.5","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"123.7","Cell RNA - K-562 [nTPM]":"1.4","Cell RNA - Karpas-707 [nTPM]":"1.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"179.4","Cell RNA - NB-4 [nTPM]":"13.3","Cell RNA - NTERA-2 [nTPM]":"2.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"19.1","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"4.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.8","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"5.7","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"65.5","Cell RNA - U-266\/84 [nTPM]":"56.8","Cell RNA - U-698 [nTPM]":"116.3","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"4.4","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"210.3","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"168.7","Blood RNA - gdT-cell [nTPM]":"112.2","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"99.3","Blood RNA - memory B-cell [nTPM]":"164.3","Blood RNA - memory CD4 T-cell [nTPM]":"176.9","Blood RNA - memory CD8 T-cell [nTPM]":"151.1","Blood RNA - myeloid DC [nTPM]":"1.9","Blood RNA - naive B-cell [nTPM]":"212.1","Blood RNA - naive CD4 T-cell [nTPM]":"274.3","Blood RNA - naive CD8 T-cell [nTPM]":"220.5","Blood RNA - neutrophil [nTPM]":"8.4","Blood RNA - NK-cell [nTPM]":"74.2","Blood RNA - non-classical monocyte [nTPM]":"1.2","Blood RNA - plasmacytoid DC [nTPM]":"26.1","Blood RNA - T-reg [nTPM]":"268.4","Blood RNA - total PBMC [nTPM]":"124.1","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"0.8","Brain RNA - hippocampal formation [nTPM]":"0.6","Brain RNA - hypothalamus [nTPM]":"0.8","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"1.3","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"0.8","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"2.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"273.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"2.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"90.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"2.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"23.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"3.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.0","Single Cell Type RNA - granulocytes [nTPM]":"141.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.4","Single Cell Type RNA - Langerhans cells [nTPM]":"16.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"28.4","Single Cell Type RNA - Melanocytes [nTPM]":"56.9","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"11.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"64.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"183.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"223.6","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"2.0"},{"Gene":"RIN2","Gene synonym":["RASSF4"],"Ensembl":"ENSG00000132669","Gene description":"Ras and Rab interactor 2","Uniprot":["Q8WYP3"],"Chromosome":"20","Position":"19757606-20002457","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Endocytosis"],"Molecular function":["GTPase activation"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"198.5","Microglial cells":"191.1","Oligodendrocyte precursor cells":"296.6","Oligodendrocytes":"202.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"classical monocyte":"1.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"PC-3":"47.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA034641"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoli","Golgi apparatus"],"Antibody RRID":{"HPA034641":"AB_10671230"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.23e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.09e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.34e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Tissue RNA - adipose tissue [nTPM]":"14.2","Tissue RNA - adrenal gland [nTPM]":"6.4","Tissue RNA - amygdala [nTPM]":"8.7","Tissue RNA - appendix [nTPM]":"8.6","Tissue RNA - basal ganglia [nTPM]":"13.5","Tissue RNA - bone marrow [nTPM]":"6.1","Tissue RNA - breast [nTPM]":"9.5","Tissue RNA - cerebellum [nTPM]":"9.4","Tissue RNA - cerebral cortex [nTPM]":"7.1","Tissue RNA - cervix [nTPM]":"14.4","Tissue RNA - choroid plexus [nTPM]":"14.4","Tissue RNA - colon [nTPM]":"12.5","Tissue RNA - duodenum [nTPM]":"13.3","Tissue RNA - endometrium 1 [nTPM]":"14.1","Tissue RNA - epididymis [nTPM]":"3.9","Tissue RNA - esophagus [nTPM]":"13.6","Tissue RNA - fallopian tube [nTPM]":"11.7","Tissue RNA - gallbladder [nTPM]":"17.8","Tissue RNA - heart muscle [nTPM]":"18.7","Tissue RNA - hippocampal formation [nTPM]":"9.5","Tissue RNA - hypothalamus [nTPM]":"10.8","Tissue RNA - kidney [nTPM]":"12.1","Tissue RNA - liver [nTPM]":"5.3","Tissue RNA - lung [nTPM]":"18.3","Tissue RNA - lymph node [nTPM]":"4.7","Tissue RNA - medulla oblongata [nTPM]":"14.6","Tissue RNA - midbrain [nTPM]":"13.2","Tissue RNA - ovary [nTPM]":"15.0","Tissue RNA - pancreas [nTPM]":"6.5","Tissue RNA - parathyroid gland [nTPM]":"4.6","Tissue RNA - pituitary gland [nTPM]":"1.4","Tissue RNA - placenta [nTPM]":"19.8","Tissue RNA - pons [nTPM]":"12.8","Tissue RNA - prostate [nTPM]":"9.4","Tissue RNA - rectum [nTPM]":"12.7","Tissue RNA - retina [nTPM]":"5.5","Tissue RNA - salivary gland [nTPM]":"15.6","Tissue RNA - seminal vesicle [nTPM]":"13.5","Tissue RNA - skeletal muscle [nTPM]":"9.4","Tissue RNA - skin 1 [nTPM]":"8.2","Tissue RNA - small intestine [nTPM]":"14.7","Tissue RNA - smooth muscle [nTPM]":"16.2","Tissue RNA - spinal cord [nTPM]":"9.5","Tissue RNA - spleen [nTPM]":"16.8","Tissue RNA - stomach 1 [nTPM]":"8.8","Tissue RNA - testis [nTPM]":"1.8","Tissue RNA - thalamus [nTPM]":"12.7","Tissue RNA - thymus [nTPM]":"3.0","Tissue RNA - thyroid gland [nTPM]":"13.7","Tissue RNA - tongue [nTPM]":"13.2","Tissue RNA - tonsil [nTPM]":"5.3","Tissue RNA - urinary bladder [nTPM]":"8.1","Tissue RNA - vagina [nTPM]":"3.8","Tissue RNA - white matter [nTPM]":"14.0","Cell RNA - A-431 [nTPM]":"6.7","Cell RNA - A549 [nTPM]":"22.4","Cell RNA - AF22 [nTPM]":"4.1","Cell RNA - AN3-CA [nTPM]":"13.7","Cell RNA - ASC diff [nTPM]":"23.3","Cell RNA - ASC TERT1 [nTPM]":"14.2","Cell RNA - BEWO [nTPM]":"13.1","Cell RNA - BJ [nTPM]":"5.9","Cell RNA - BJ hTERT+ [nTPM]":"22.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.0","Cell RNA - CACO-2 [nTPM]":"10.0","Cell RNA - CAPAN-2 [nTPM]":"5.8","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"24.0","Cell RNA - fHDF\/TERT166 [nTPM]":"14.6","Cell RNA - GAMG [nTPM]":"10.6","Cell RNA - HaCaT [nTPM]":"24.7","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"33.5","Cell RNA - HBF TERT88 [nTPM]":"6.3","Cell RNA - HDLM-2 [nTPM]":"2.7","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"3.5","Cell RNA - Hep G2 [nTPM]":"0.8","Cell RNA - HHSteC [nTPM]":"5.4","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"21.7","Cell RNA - hTCEpi [nTPM]":"6.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.7","Cell RNA - hTERT-HME1 [nTPM]":"11.9","Cell RNA - hTERT-RPE1 [nTPM]":"13.4","Cell RNA - HUVEC TERT2 [nTPM]":"30.6","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"17.0","Cell RNA - MCF7 [nTPM]":"5.3","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"3.2","Cell RNA - PC-3 [nTPM]":"47.1","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"13.8","Cell RNA - RPMI-8226 [nTPM]":"3.4","Cell RNA - RPTEC TERT1 [nTPM]":"7.2","Cell RNA - RT4 [nTPM]":"9.2","Cell RNA - SCLC-21H [nTPM]":"3.5","Cell RNA - SH-SY5Y [nTPM]":"0.9","Cell RNA - SiHa [nTPM]":"5.3","Cell RNA - SK-BR-3 [nTPM]":"23.7","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"4.1","Cell RNA - T-47d [nTPM]":"2.0","Cell RNA - THP-1 [nTPM]":"1.4","Cell RNA - TIME [nTPM]":"33.7","Cell RNA - U-138 MG [nTPM]":"11.4","Cell RNA - U-2 OS [nTPM]":"2.9","Cell RNA - U-2197 [nTPM]":"8.1","Cell RNA - U-251 MG [nTPM]":"9.2","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"8.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"2.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"1.6","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.8","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"1.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"8.7","Brain RNA - basal ganglia [nTPM]":"13.5","Brain RNA - cerebellum [nTPM]":"9.4","Brain RNA - cerebral cortex [nTPM]":"7.1","Brain RNA - hippocampal formation [nTPM]":"9.5","Brain RNA - hypothalamus [nTPM]":"10.8","Brain RNA - medulla oblongata [nTPM]":"14.6","Brain RNA - midbrain [nTPM]":"13.2","Brain RNA - pons [nTPM]":"12.8","Brain RNA - spinal cord [nTPM]":"9.5","Brain RNA - thalamus [nTPM]":"12.7","Brain RNA - white matter [nTPM]":"14.0","Single Cell Type RNA - Adipocytes [nTPM]":"52.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"64.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.5","Single Cell Type RNA - Astrocytes [nTPM]":"198.5","Single Cell Type RNA - B-cells [nTPM]":"1.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"41.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"6.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"34.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"23.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.8","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"30.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"43.0","Single Cell Type RNA - Ductal cells [nTPM]":"17.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"50.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"47.3","Single Cell Type RNA - Endothelial cells [nTPM]":"52.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"34.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.4","Single Cell Type RNA - Fibroblasts [nTPM]":"33.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"87.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"32.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"105.3","Single Cell Type RNA - Hepatocytes [nTPM]":"4.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"100.2","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"82.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.2","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"60.3","Single Cell Type RNA - Langerhans cells [nTPM]":"40.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"19.3","Single Cell Type RNA - Macrophages [nTPM]":"37.7","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"191.1","Single Cell Type RNA - monocytes [nTPM]":"21.4","Single Cell Type RNA - Muller glia cells [nTPM]":"33.2","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"296.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"202.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"26.2","Single Cell Type RNA - Paneth cells [nTPM]":"10.5","Single Cell Type RNA - Peritubular cells [nTPM]":"15.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"22.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"50.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"27.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"33.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"54.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.1","Single Cell Type RNA - T-cells [nTPM]":"2.9","Single Cell Type RNA - Theca cells [nTPM]":"43.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"21.9","Single Cell Type RNA - Urothelial cells [nTPM]":"32.2"},{"Gene":"RNF113A","Gene synonym":["Cwc24","RNF113","ZNF183"],"Ensembl":"ENSG00000125352","Gene description":"Ring finger protein 113A","Uniprot":["O15541"],"Chromosome":"X","Position":"119870475-119871733","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","mRNA processing","mRNA splicing","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000160","HPA076658"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA000160":"AB_1079821","HPA076658":"AB_2732319"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.93e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.23e-4"},"Tissue RNA - adipose tissue [nTPM]":"11.0","Tissue RNA - adrenal gland [nTPM]":"9.6","Tissue RNA - amygdala [nTPM]":"11.5","Tissue RNA - appendix [nTPM]":"13.0","Tissue RNA - basal ganglia [nTPM]":"12.1","Tissue RNA - bone marrow [nTPM]":"35.3","Tissue RNA - breast [nTPM]":"10.2","Tissue RNA - cerebellum [nTPM]":"13.0","Tissue RNA - cerebral cortex [nTPM]":"14.4","Tissue RNA - cervix [nTPM]":"10.5","Tissue RNA - choroid plexus [nTPM]":"11.3","Tissue RNA - colon [nTPM]":"11.4","Tissue RNA - duodenum [nTPM]":"13.2","Tissue RNA - endometrium 1 [nTPM]":"9.8","Tissue RNA - epididymis [nTPM]":"9.6","Tissue RNA - esophagus [nTPM]":"11.3","Tissue RNA - fallopian tube [nTPM]":"10.2","Tissue RNA - gallbladder [nTPM]":"8.2","Tissue RNA - heart muscle [nTPM]":"12.7","Tissue RNA - hippocampal formation [nTPM]":"11.7","Tissue RNA - hypothalamus [nTPM]":"13.9","Tissue RNA - kidney [nTPM]":"9.2","Tissue RNA - liver [nTPM]":"17.7","Tissue RNA - lung [nTPM]":"11.0","Tissue RNA - lymph node [nTPM]":"24.7","Tissue RNA - medulla oblongata [nTPM]":"12.7","Tissue RNA - midbrain [nTPM]":"13.0","Tissue RNA - ovary [nTPM]":"13.4","Tissue RNA - pancreas [nTPM]":"19.1","Tissue RNA - parathyroid gland [nTPM]":"9.2","Tissue RNA - pituitary gland [nTPM]":"10.0","Tissue RNA - placenta [nTPM]":"9.0","Tissue RNA - pons [nTPM]":"13.1","Tissue RNA - prostate [nTPM]":"8.9","Tissue RNA - rectum [nTPM]":"9.5","Tissue RNA - retina [nTPM]":"15.6","Tissue RNA - salivary gland [nTPM]":"14.4","Tissue RNA - seminal vesicle [nTPM]":"8.8","Tissue RNA - skeletal muscle [nTPM]":"12.3","Tissue RNA - skin 1 [nTPM]":"17.1","Tissue RNA - small intestine [nTPM]":"17.5","Tissue RNA - smooth muscle [nTPM]":"7.5","Tissue RNA - spinal cord [nTPM]":"11.9","Tissue RNA - spleen [nTPM]":"24.3","Tissue RNA - stomach 1 [nTPM]":"12.1","Tissue RNA - testis [nTPM]":"3.4","Tissue RNA - thalamus [nTPM]":"13.1","Tissue RNA - thymus [nTPM]":"24.7","Tissue RNA - thyroid gland [nTPM]":"9.9","Tissue RNA - tongue [nTPM]":"10.6","Tissue RNA - tonsil [nTPM]":"19.0","Tissue RNA - urinary bladder [nTPM]":"10.8","Tissue RNA - vagina [nTPM]":"10.3","Tissue RNA - white matter [nTPM]":"12.6","Cell RNA - A-431 [nTPM]":"16.9","Cell RNA - A549 [nTPM]":"22.9","Cell RNA - AF22 [nTPM]":"11.0","Cell RNA - AN3-CA [nTPM]":"17.7","Cell RNA - ASC diff [nTPM]":"20.7","Cell RNA - ASC TERT1 [nTPM]":"14.9","Cell RNA - BEWO [nTPM]":"22.3","Cell RNA - BJ [nTPM]":"14.8","Cell RNA - BJ hTERT+ [nTPM]":"25.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.0","Cell RNA - CACO-2 [nTPM]":"19.7","Cell RNA - CAPAN-2 [nTPM]":"14.1","Cell RNA - Daudi [nTPM]":"28.0","Cell RNA - EFO-21 [nTPM]":"28.1","Cell RNA - fHDF\/TERT166 [nTPM]":"13.8","Cell RNA - GAMG [nTPM]":"25.1","Cell RNA - HaCaT [nTPM]":"20.4","Cell RNA - HAP1 [nTPM]":"24.4","Cell RNA - HBEC3-KT [nTPM]":"19.1","Cell RNA - HBF TERT88 [nTPM]":"13.1","Cell RNA - HDLM-2 [nTPM]":"21.9","Cell RNA - HEK 293 [nTPM]":"18.0","Cell RNA - HEL [nTPM]":"17.0","Cell RNA - HeLa [nTPM]":"25.8","Cell RNA - Hep G2 [nTPM]":"23.5","Cell RNA - HHSteC [nTPM]":"28.3","Cell RNA - HL-60 [nTPM]":"33.7","Cell RNA - HMC-1 [nTPM]":"28.3","Cell RNA - HSkMC [nTPM]":"18.4","Cell RNA - hTCEpi [nTPM]":"20.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.7","Cell RNA - hTERT-HME1 [nTPM]":"26.0","Cell RNA - hTERT-RPE1 [nTPM]":"20.7","Cell RNA - HUVEC TERT2 [nTPM]":"17.1","Cell RNA - JURKAT [nTPM]":"19.4","Cell RNA - K-562 [nTPM]":"12.2","Cell RNA - Karpas-707 [nTPM]":"38.4","Cell RNA - LHCN-M2 [nTPM]":"17.3","Cell RNA - MCF7 [nTPM]":"47.5","Cell RNA - MOLT-4 [nTPM]":"23.5","Cell RNA - NB-4 [nTPM]":"39.9","Cell RNA - NTERA-2 [nTPM]":"16.1","Cell RNA - OE19 [nTPM]":"29.5","Cell RNA - PC-3 [nTPM]":"32.8","Cell RNA - REH [nTPM]":"21.7","Cell RNA - RH-30 [nTPM]":"23.2","Cell RNA - RPMI-8226 [nTPM]":"45.3","Cell RNA - RPTEC TERT1 [nTPM]":"18.5","Cell RNA - RT4 [nTPM]":"20.6","Cell RNA - SCLC-21H [nTPM]":"14.7","Cell RNA - SH-SY5Y [nTPM]":"12.9","Cell RNA - SiHa [nTPM]":"23.1","Cell RNA - SK-BR-3 [nTPM]":"35.5","Cell RNA - SK-MEL-30 [nTPM]":"33.1","Cell RNA - SuSa [nTPM]":"12.9","Cell RNA - T-47d [nTPM]":"8.7","Cell RNA - THP-1 [nTPM]":"32.9","Cell RNA - TIME [nTPM]":"13.1","Cell RNA - U-138 MG [nTPM]":"18.6","Cell RNA - U-2 OS [nTPM]":"6.6","Cell RNA - U-2197 [nTPM]":"26.7","Cell RNA - U-251 MG [nTPM]":"29.7","Cell RNA - U-266\/70 [nTPM]":"43.2","Cell RNA - U-266\/84 [nTPM]":"36.0","Cell RNA - U-698 [nTPM]":"27.9","Cell RNA - U-87 MG [nTPM]":"16.8","Cell RNA - U-937 [nTPM]":"44.1","Cell RNA - WM-115 [nTPM]":"12.3","Blood RNA - basophil [nTPM]":"96.4","Blood RNA - classical monocyte [nTPM]":"59.5","Blood RNA - eosinophil [nTPM]":"109.5","Blood RNA - gdT-cell [nTPM]":"73.9","Blood RNA - intermediate monocyte [nTPM]":"60.3","Blood RNA - MAIT T-cell [nTPM]":"74.4","Blood RNA - memory B-cell [nTPM]":"83.6","Blood RNA - memory CD4 T-cell [nTPM]":"78.3","Blood RNA - memory CD8 T-cell [nTPM]":"79.0","Blood RNA - myeloid DC [nTPM]":"63.4","Blood RNA - naive B-cell [nTPM]":"88.6","Blood RNA - naive CD4 T-cell [nTPM]":"81.3","Blood RNA - naive CD8 T-cell [nTPM]":"73.1","Blood RNA - neutrophil [nTPM]":"27.5","Blood RNA - NK-cell [nTPM]":"65.9","Blood RNA - non-classical monocyte [nTPM]":"72.6","Blood RNA - plasmacytoid DC [nTPM]":"53.3","Blood RNA - T-reg [nTPM]":"96.6","Blood RNA - total PBMC [nTPM]":"73.6","Brain RNA - amygdala [nTPM]":"11.5","Brain RNA - basal ganglia [nTPM]":"12.1","Brain RNA - cerebellum [nTPM]":"13.0","Brain RNA - cerebral cortex [nTPM]":"14.4","Brain RNA - hippocampal formation [nTPM]":"11.7","Brain RNA - hypothalamus [nTPM]":"13.9","Brain RNA - medulla oblongata [nTPM]":"12.7","Brain RNA - midbrain [nTPM]":"13.0","Brain RNA - pons [nTPM]":"13.1","Brain RNA - spinal cord [nTPM]":"11.9","Brain RNA - thalamus [nTPM]":"13.1","Brain RNA - white matter [nTPM]":"12.6","Single Cell Type RNA - Adipocytes [nTPM]":"14.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.8","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"42.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"26.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"30.7","Single Cell Type RNA - Bipolar cells [nTPM]":"11.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"21.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.5","Single Cell Type RNA - dendritic cells [nTPM]":"51.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"18.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.8","Single Cell Type RNA - Endothelial cells [nTPM]":"17.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"10.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"37.6","Single Cell Type RNA - Fibroblasts [nTPM]":"15.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.5","Single Cell Type RNA - granulocytes [nTPM]":"26.5","Single Cell Type RNA - Granulosa cells [nTPM]":"14.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.2","Single Cell Type RNA - Hepatocytes [nTPM]":"13.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.4","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.8","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"17.6","Single Cell Type RNA - Langerhans cells [nTPM]":"23.1","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"12.2","Single Cell Type RNA - Macrophages [nTPM]":"17.0","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"17.2","Single Cell Type RNA - Muller glia cells [nTPM]":"16.5","Single Cell Type RNA - NK-cells [nTPM]":"39.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.5","Single Cell Type RNA - Paneth cells [nTPM]":"17.8","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"59.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"34.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"25.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.3","Single Cell Type RNA - Spermatocytes [nTPM]":"2.9","Single Cell Type RNA - Spermatogonia [nTPM]":"5.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"26.4","Single Cell Type RNA - T-cells [nTPM]":"50.2","Single Cell Type RNA - Theca cells [nTPM]":"15.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.5","Single Cell Type RNA - Urothelial cells [nTPM]":"14.3"},{"Gene":"RPL21","Gene synonym":["DKFZp686C06101","FLJ27458","L21","MGC104274","MGC104275","MGC71252"],"Ensembl":"ENSG00000122026","Gene description":"Ribosomal protein L21","Uniprot":["P46778"],"Chromosome":"13","Position":"27251309-27256691","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Ribosomal proteins"],"Biological process":null,"Molecular function":["Ribonucleoprotein","Ribosomal protein"],"Disease involvement":["Disease variant","Hypotrichosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047252"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli fibrillar center","Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"34000","Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 32: Non-specific - Translation","Subcellular main location":["Nucleoli fibrillar center","Endoplasmic reticulum","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA047252":"AB_2680000"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.66e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Tissue RNA - adipose tissue [nTPM]":"1565.0","Tissue RNA - adrenal gland [nTPM]":"1042.6","Tissue RNA - amygdala [nTPM]":"1087.8","Tissue RNA - appendix [nTPM]":"714.2","Tissue RNA - basal ganglia [nTPM]":"1108.1","Tissue RNA - bone marrow [nTPM]":"2293.7","Tissue RNA - breast [nTPM]":"1689.3","Tissue RNA - cerebellum [nTPM]":"1066.4","Tissue RNA - cerebral cortex [nTPM]":"1946.8","Tissue RNA - cervix [nTPM]":"2047.0","Tissue RNA - choroid plexus [nTPM]":"1061.5","Tissue RNA - colon [nTPM]":"1733.4","Tissue RNA - duodenum [nTPM]":"625.1","Tissue RNA - endometrium 1 [nTPM]":"1329.1","Tissue RNA - epididymis [nTPM]":"725.7","Tissue RNA - esophagus [nTPM]":"1504.9","Tissue RNA - fallopian tube [nTPM]":"1718.1","Tissue RNA - gallbladder [nTPM]":"553.6","Tissue RNA - heart muscle [nTPM]":"1306.5","Tissue RNA - hippocampal formation [nTPM]":"1047.9","Tissue RNA - hypothalamus [nTPM]":"1131.1","Tissue RNA - kidney [nTPM]":"1421.7","Tissue RNA - liver [nTPM]":"1085.9","Tissue RNA - lung [nTPM]":"1181.3","Tissue RNA - lymph node [nTPM]":"1633.8","Tissue RNA - medulla oblongata [nTPM]":"1112.2","Tissue RNA - midbrain [nTPM]":"1089.9","Tissue RNA - ovary [nTPM]":"3100.5","Tissue RNA - pancreas [nTPM]":"2449.9","Tissue RNA - parathyroid gland [nTPM]":"514.5","Tissue RNA - pituitary gland [nTPM]":"1047.0","Tissue RNA - placenta [nTPM]":"626.6","Tissue RNA - pons [nTPM]":"1107.4","Tissue RNA - prostate [nTPM]":"1381.0","Tissue RNA - rectum [nTPM]":"803.3","Tissue RNA - retina [nTPM]":"419.1","Tissue RNA - salivary gland [nTPM]":"1325.3","Tissue RNA - seminal vesicle [nTPM]":"643.2","Tissue RNA - skeletal muscle [nTPM]":"1855.2","Tissue RNA - skin 1 [nTPM]":"1987.4","Tissue RNA - small intestine [nTPM]":"1471.7","Tissue RNA - smooth muscle [nTPM]":"594.3","Tissue RNA - spinal cord [nTPM]":"1106.4","Tissue RNA - spleen [nTPM]":"1794.1","Tissue RNA - stomach 1 [nTPM]":"1487.8","Tissue RNA - testis [nTPM]":"317.3","Tissue RNA - thalamus [nTPM]":"1103.9","Tissue RNA - thymus [nTPM]":"1072.9","Tissue RNA - thyroid gland [nTPM]":"1114.9","Tissue RNA - tongue [nTPM]":"769.6","Tissue RNA - tonsil [nTPM]":"1395.1","Tissue RNA - urinary bladder [nTPM]":"1631.4","Tissue RNA - vagina [nTPM]":"1650.9","Tissue RNA - white matter [nTPM]":"1117.2","Cell RNA - A-431 [nTPM]":"942.9","Cell RNA - A549 [nTPM]":"772.1","Cell RNA - AF22 [nTPM]":"1337.0","Cell RNA - AN3-CA [nTPM]":"1086.2","Cell RNA - ASC diff [nTPM]":"1361.4","Cell RNA - ASC TERT1 [nTPM]":"2569.1","Cell RNA - BEWO [nTPM]":"1130.1","Cell RNA - BJ [nTPM]":"1664.7","Cell RNA - BJ hTERT+ [nTPM]":"1515.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1277.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"822.1","Cell RNA - CACO-2 [nTPM]":"1875.1","Cell RNA - CAPAN-2 [nTPM]":"1700.0","Cell RNA - Daudi [nTPM]":"3578.7","Cell RNA - EFO-21 [nTPM]":"627.8","Cell RNA - fHDF\/TERT166 [nTPM]":"1332.5","Cell RNA - GAMG [nTPM]":"571.7","Cell RNA - HaCaT [nTPM]":"1220.3","Cell RNA - HAP1 [nTPM]":"1552.8","Cell RNA - HBEC3-KT [nTPM]":"1694.0","Cell RNA - HBF TERT88 [nTPM]":"1495.8","Cell RNA - HDLM-2 [nTPM]":"1139.5","Cell RNA - HEK 293 [nTPM]":"1410.3","Cell RNA - HEL [nTPM]":"2803.5","Cell RNA - HeLa [nTPM]":"738.9","Cell RNA - Hep G2 [nTPM]":"1470.3","Cell RNA - HHSteC [nTPM]":"1284.7","Cell RNA - HL-60 [nTPM]":"3871.3","Cell RNA - HMC-1 [nTPM]":"1063.8","Cell RNA - HSkMC [nTPM]":"2304.6","Cell RNA - hTCEpi [nTPM]":"2722.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"837.5","Cell RNA - hTERT-HME1 [nTPM]":"2112.0","Cell RNA - hTERT-RPE1 [nTPM]":"1751.9","Cell RNA - HUVEC TERT2 [nTPM]":"1454.0","Cell RNA - JURKAT [nTPM]":"1562.9","Cell RNA - K-562 [nTPM]":"1181.8","Cell RNA - Karpas-707 [nTPM]":"865.5","Cell RNA - LHCN-M2 [nTPM]":"1468.6","Cell RNA - MCF7 [nTPM]":"1340.3","Cell RNA - MOLT-4 [nTPM]":"1970.6","Cell RNA - NB-4 [nTPM]":"2398.9","Cell RNA - NTERA-2 [nTPM]":"1754.3","Cell RNA - OE19 [nTPM]":"2792.4","Cell RNA - PC-3 [nTPM]":"1281.4","Cell RNA - REH [nTPM]":"1446.1","Cell RNA - RH-30 [nTPM]":"2566.6","Cell RNA - RPMI-8226 [nTPM]":"1511.2","Cell RNA - RPTEC TERT1 [nTPM]":"1201.2","Cell RNA - RT4 [nTPM]":"1111.2","Cell RNA - SCLC-21H [nTPM]":"1153.8","Cell RNA - SH-SY5Y [nTPM]":"1071.6","Cell RNA - SiHa [nTPM]":"773.3","Cell RNA - SK-BR-3 [nTPM]":"1531.6","Cell RNA - SK-MEL-30 [nTPM]":"1390.1","Cell RNA - SuSa [nTPM]":"1120.4","Cell RNA - T-47d [nTPM]":"1033.9","Cell RNA - THP-1 [nTPM]":"3406.6","Cell RNA - TIME [nTPM]":"1619.7","Cell RNA - U-138 MG [nTPM]":"563.1","Cell RNA - U-2 OS [nTPM]":"731.3","Cell RNA - U-2197 [nTPM]":"895.3","Cell RNA - U-251 MG [nTPM]":"1384.6","Cell RNA - U-266\/70 [nTPM]":"579.7","Cell RNA - U-266\/84 [nTPM]":"874.2","Cell RNA - U-698 [nTPM]":"2583.3","Cell RNA - U-87 MG [nTPM]":"722.1","Cell RNA - U-937 [nTPM]":"2415.5","Cell RNA - WM-115 [nTPM]":"978.6","Blood RNA - basophil [nTPM]":"948.5","Blood RNA - classical monocyte [nTPM]":"1201.5","Blood RNA - eosinophil [nTPM]":"493.2","Blood RNA - gdT-cell [nTPM]":"1996.0","Blood RNA - intermediate monocyte [nTPM]":"1257.2","Blood RNA - MAIT T-cell [nTPM]":"3233.0","Blood RNA - memory B-cell [nTPM]":"3717.7","Blood RNA - memory CD4 T-cell [nTPM]":"2993.5","Blood RNA - memory CD8 T-cell [nTPM]":"2504.4","Blood RNA - myeloid DC [nTPM]":"1607.9","Blood RNA - naive B-cell [nTPM]":"3347.5","Blood RNA - naive CD4 T-cell [nTPM]":"4294.2","Blood RNA - naive CD8 T-cell [nTPM]":"3510.3","Blood RNA - neutrophil [nTPM]":"249.1","Blood RNA - NK-cell [nTPM]":"2178.4","Blood RNA - non-classical monocyte [nTPM]":"1308.5","Blood RNA - plasmacytoid DC [nTPM]":"2181.4","Blood RNA - T-reg [nTPM]":"2271.1","Blood RNA - total PBMC [nTPM]":"6723.7","Brain RNA - amygdala [nTPM]":"1087.8","Brain RNA - basal ganglia [nTPM]":"1108.1","Brain RNA - cerebellum [nTPM]":"1066.4","Brain RNA - cerebral cortex [nTPM]":"1946.8","Brain RNA - hippocampal formation [nTPM]":"1047.9","Brain RNA - hypothalamus [nTPM]":"1131.1","Brain RNA - medulla oblongata [nTPM]":"1112.2","Brain RNA - midbrain [nTPM]":"1089.9","Brain RNA - pons [nTPM]":"1107.4","Brain RNA - spinal cord [nTPM]":"1106.4","Brain RNA - thalamus [nTPM]":"1103.9","Brain RNA - white matter [nTPM]":"1117.2","Single Cell Type RNA - Adipocytes [nTPM]":"1464.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"1685.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2658.5","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"6395.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7645.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5673.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7552.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1649.3","Single Cell Type RNA - Bipolar cells [nTPM]":"375.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"4496.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3380.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"191.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"4000.5","Single Cell Type RNA - Club cells [nTPM]":"3789.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"1565.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"143.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5240.1","Single Cell Type RNA - dendritic cells [nTPM]":"4382.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"1695.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"5290.4","Single Cell Type RNA - Ductal cells [nTPM]":"3849.1","Single Cell Type RNA - Early spermatids [nTPM]":"74.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1089.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2417.7","Single Cell Type RNA - Endothelial cells [nTPM]":"2670.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2385.5","Single Cell Type RNA - Erythroid cells [nTPM]":"4124.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7829.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6183.8","Single Cell Type RNA - Fibroblasts [nTPM]":"2401.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"924.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1200.5","Single Cell Type RNA - granulocytes [nTPM]":"2817.5","Single Cell Type RNA - Granulosa cells [nTPM]":"2227.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4446.9","Single Cell Type RNA - Hepatocytes [nTPM]":"4944.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"3952.9","Single Cell Type RNA - Horizontal cells [nTPM]":"159.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4869.4","Single Cell Type RNA - Ionocytes [nTPM]":"2518.7","Single Cell Type RNA - Kupffer cells [nTPM]":"7461.4","Single Cell Type RNA - Langerhans cells [nTPM]":"9266.1","Single Cell Type RNA - Late spermatids [nTPM]":"225.9","Single Cell Type RNA - Leydig cells [nTPM]":"3957.2","Single Cell Type RNA - Macrophages [nTPM]":"3114.0","Single Cell Type RNA - Melanocytes [nTPM]":"5229.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"9465.6","Single Cell Type RNA - Muller glia cells [nTPM]":"1525.3","Single Cell Type RNA - NK-cells [nTPM]":"6167.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4983.3","Single Cell Type RNA - Paneth cells [nTPM]":"3923.7","Single Cell Type RNA - Peritubular cells [nTPM]":"2403.1","Single Cell Type RNA - Plasma cells [nTPM]":"2133.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4379.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4261.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6230.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1742.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"634.1","Single Cell Type RNA - Sertoli cells [nTPM]":"1899.8","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4878.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2645.8","Single Cell Type RNA - Spermatocytes [nTPM]":"650.7","Single Cell Type RNA - Spermatogonia [nTPM]":"1016.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2107.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8226.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5507.4","Single Cell Type RNA - T-cells [nTPM]":"5413.5","Single Cell Type RNA - Theca cells [nTPM]":"1829.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5416.3","Single Cell Type RNA - Urothelial cells [nTPM]":"4837.4"},{"Gene":"RSPO4","Gene synonym":["C20orf182","dJ824F16.3"],"Ensembl":"ENSG00000101282","Gene description":"R-spondin 4","Uniprot":["Q2I0M5"],"Chromosome":"20","Position":"958452-1002311","Protein class":["Disease related genes","Human disease related genes","Predicted secreted proteins"],"Biological process":["Sensory transduction","Wnt signaling pathway"],"Molecular function":["Heparin-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"13.0","lung":"12.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"10.7","Early spermatids":"6.6","Late spermatids":"7.3","Oligodendrocyte precursor cells":"8.5","Oligodendrocytes":"7.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"6.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"3.0","EFO-21":"2.0","fHDF\/TERT166":"2.4","NTERA-2":"6.3","SK-BR-3":"4.3","U-2 OS":"6.9"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"1.2"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048887"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048887":"AB_2680545"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.98e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.26e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.18e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"4.3","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"4.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"1.3","Tissue RNA - cerebellum [nTPM]":"2.1","Tissue RNA - cerebral cortex [nTPM]":"6.7","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"1.1","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"0.8","Tissue RNA - fallopian tube [nTPM]":"1.6","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.5","Tissue RNA - hippocampal formation [nTPM]":"3.4","Tissue RNA - hypothalamus [nTPM]":"7.6","Tissue RNA - kidney [nTPM]":"0.6","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"12.6","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"13.0","Tissue RNA - midbrain [nTPM]":"8.4","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"12.6","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"1.2","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"3.0","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"3.8","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"3.2","Tissue RNA - thalamus [nTPM]":"9.6","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"3.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"2.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"3.0","Cell RNA - BJ [nTPM]":"1.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.8","Cell RNA - EFO-21 [nTPM]":"2.0","Cell RNA - fHDF\/TERT166 [nTPM]":"2.4","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"6.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"4.3","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"6.9","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"1.4","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.3","Brain RNA - basal ganglia [nTPM]":"4.6","Brain RNA - cerebellum [nTPM]":"2.1","Brain RNA - cerebral cortex [nTPM]":"6.7","Brain RNA - hippocampal formation [nTPM]":"3.4","Brain RNA - hypothalamus [nTPM]":"7.6","Brain RNA - medulla oblongata [nTPM]":"13.0","Brain RNA - midbrain [nTPM]":"8.4","Brain RNA - pons [nTPM]":"12.6","Brain RNA - spinal cord [nTPM]":"3.8","Brain RNA - thalamus [nTPM]":"9.6","Brain RNA - white matter [nTPM]":"2.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.7","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"6.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.6","Single Cell Type RNA - Fibroblasts [nTPM]":"0.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.8","Single Cell Type RNA - Late spermatids [nTPM]":"7.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.5","Single Cell Type RNA - Spermatocytes [nTPM]":"2.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SASH1","Gene synonym":["dJ323M4.1","KIAA0790","SH3D6A"],"Ensembl":"ENSG00000111961","Gene description":"SAM and SH3 domain containing 1","Uniprot":["O94885"],"Chromosome":"6","Position":"148272304-148552048","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Hypotrichosis","Palmoplantar keratoderma","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"194.8","Astrocytes":"426.7","Microglial cells":"179.9","Oligodendrocyte precursor cells":"186.5","Oligodendrocytes":"328.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"17","RNA blood cell specific nTPM":{"classical monocyte":"1.2","intermediate monocyte":"2.6","non-classical monocyte":"1.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"26","RNA blood lineage specific nTPM":{"monocytes":"2.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"198.0","ASC TERT1":"74.7","fHDF\/TERT166":"73.4","HUVEC TERT2":"75.0","WM-115":"95.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA029947","HPA029949"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA029947":"AB_10598915","HPA029949":"AB_10602280"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.42e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.76e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Tissue RNA - adipose tissue [nTPM]":"76.1","Tissue RNA - adrenal gland [nTPM]":"6.1","Tissue RNA - amygdala [nTPM]":"45.5","Tissue RNA - appendix [nTPM]":"6.6","Tissue RNA - basal ganglia [nTPM]":"62.5","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"47.6","Tissue RNA - cerebellum [nTPM]":"58.2","Tissue RNA - cerebral cortex [nTPM]":"35.4","Tissue RNA - cervix [nTPM]":"24.5","Tissue RNA - choroid plexus [nTPM]":"10.3","Tissue RNA - colon [nTPM]":"18.1","Tissue RNA - duodenum [nTPM]":"6.8","Tissue RNA - endometrium 1 [nTPM]":"13.6","Tissue RNA - epididymis [nTPM]":"5.1","Tissue RNA - esophagus [nTPM]":"45.2","Tissue RNA - fallopian tube [nTPM]":"15.9","Tissue RNA - gallbladder [nTPM]":"19.7","Tissue RNA - heart muscle [nTPM]":"17.0","Tissue RNA - hippocampal formation [nTPM]":"40.0","Tissue RNA - hypothalamus [nTPM]":"43.0","Tissue RNA - kidney [nTPM]":"15.0","Tissue RNA - liver [nTPM]":"9.3","Tissue RNA - lung [nTPM]":"26.5","Tissue RNA - lymph node [nTPM]":"6.2","Tissue RNA - medulla oblongata [nTPM]":"72.1","Tissue RNA - midbrain [nTPM]":"60.0","Tissue RNA - ovary [nTPM]":"6.5","Tissue RNA - pancreas [nTPM]":"9.5","Tissue RNA - parathyroid gland [nTPM]":"14.2","Tissue RNA - pituitary gland [nTPM]":"5.1","Tissue RNA - placenta [nTPM]":"30.3","Tissue RNA - pons [nTPM]":"59.4","Tissue RNA - prostate [nTPM]":"11.6","Tissue RNA - rectum [nTPM]":"9.8","Tissue RNA - retina [nTPM]":"15.4","Tissue RNA - salivary gland [nTPM]":"19.8","Tissue RNA - seminal vesicle [nTPM]":"9.2","Tissue RNA - skeletal muscle [nTPM]":"17.9","Tissue RNA - skin 1 [nTPM]":"31.0","Tissue RNA - small intestine [nTPM]":"11.8","Tissue RNA - smooth muscle [nTPM]":"16.1","Tissue RNA - spinal cord [nTPM]":"49.1","Tissue RNA - spleen [nTPM]":"13.7","Tissue RNA - stomach 1 [nTPM]":"9.5","Tissue RNA - testis [nTPM]":"4.6","Tissue RNA - thalamus [nTPM]":"65.1","Tissue RNA - thymus [nTPM]":"5.1","Tissue RNA - thyroid gland [nTPM]":"39.0","Tissue RNA - tongue [nTPM]":"22.5","Tissue RNA - tonsil [nTPM]":"7.8","Tissue RNA - urinary bladder [nTPM]":"13.8","Tissue RNA - vagina [nTPM]":"27.9","Tissue RNA - white matter [nTPM]":"59.3","Cell RNA - A-431 [nTPM]":"4.8","Cell RNA - A549 [nTPM]":"2.9","Cell RNA - AF22 [nTPM]":"23.6","Cell RNA - AN3-CA [nTPM]":"7.9","Cell RNA - ASC diff [nTPM]":"198.0","Cell RNA - ASC TERT1 [nTPM]":"74.7","Cell RNA - BEWO [nTPM]":"3.9","Cell RNA - BJ [nTPM]":"27.3","Cell RNA - BJ hTERT+ [nTPM]":"65.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"30.7","Cell RNA - CACO-2 [nTPM]":"6.2","Cell RNA - CAPAN-2 [nTPM]":"5.7","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"14.1","Cell RNA - fHDF\/TERT166 [nTPM]":"73.4","Cell RNA - GAMG [nTPM]":"10.1","Cell RNA - HaCaT [nTPM]":"5.7","Cell RNA - HAP1 [nTPM]":"7.3","Cell RNA - HBEC3-KT [nTPM]":"6.7","Cell RNA - HBF TERT88 [nTPM]":"16.9","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"5.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"13.6","Cell RNA - Hep G2 [nTPM]":"5.7","Cell RNA - HHSteC [nTPM]":"6.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.3","Cell RNA - HSkMC [nTPM]":"35.1","Cell RNA - hTCEpi [nTPM]":"6.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"30.6","Cell RNA - hTERT-HME1 [nTPM]":"8.3","Cell RNA - hTERT-RPE1 [nTPM]":"8.3","Cell RNA - HUVEC TERT2 [nTPM]":"75.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"19.1","Cell RNA - MCF7 [nTPM]":"5.5","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"6.9","Cell RNA - OE19 [nTPM]":"2.6","Cell RNA - PC-3 [nTPM]":"3.8","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"16.8","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"15.1","Cell RNA - RT4 [nTPM]":"15.1","Cell RNA - SCLC-21H [nTPM]":"0.9","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"8.4","Cell RNA - SK-BR-3 [nTPM]":"30.8","Cell RNA - SK-MEL-30 [nTPM]":"21.5","Cell RNA - SuSa [nTPM]":"6.1","Cell RNA - T-47d [nTPM]":"2.4","Cell RNA - THP-1 [nTPM]":"14.0","Cell RNA - TIME [nTPM]":"65.6","Cell RNA - U-138 MG [nTPM]":"19.7","Cell RNA - U-2 OS [nTPM]":"4.0","Cell RNA - U-2197 [nTPM]":"63.1","Cell RNA - U-251 MG [nTPM]":"5.9","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"31.6","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"95.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"1.2","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"2.6","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"45.5","Brain RNA - basal ganglia [nTPM]":"62.5","Brain RNA - cerebellum [nTPM]":"58.2","Brain RNA - cerebral cortex [nTPM]":"35.4","Brain RNA - hippocampal formation [nTPM]":"40.0","Brain RNA - hypothalamus [nTPM]":"43.0","Brain RNA - medulla oblongata [nTPM]":"72.1","Brain RNA - midbrain [nTPM]":"60.0","Brain RNA - pons [nTPM]":"59.4","Brain RNA - spinal cord [nTPM]":"49.1","Brain RNA - thalamus [nTPM]":"65.1","Brain RNA - white matter [nTPM]":"59.3","Single Cell Type RNA - Adipocytes [nTPM]":"194.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.7","Single Cell Type RNA - Astrocytes [nTPM]":"426.7","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"41.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"29.6","Single Cell Type RNA - Bipolar cells [nTPM]":"21.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"18.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"46.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"45.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"36.2","Single Cell Type RNA - Endothelial cells [nTPM]":"104.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"59.5","Single Cell Type RNA - Fibroblasts [nTPM]":"66.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"40.1","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"2.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"60.3","Single Cell Type RNA - Hepatocytes [nTPM]":"8.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.8","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"120.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.3","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"42.4","Single Cell Type RNA - Langerhans cells [nTPM]":"18.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"18.3","Single Cell Type RNA - Macrophages [nTPM]":"15.6","Single Cell Type RNA - Melanocytes [nTPM]":"42.7","Single Cell Type RNA - Microglial cells [nTPM]":"179.9","Single Cell Type RNA - monocytes [nTPM]":"4.9","Single Cell Type RNA - Muller glia cells [nTPM]":"100.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"186.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"328.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.5","Single Cell Type RNA - Paneth cells [nTPM]":"2.9","Single Cell Type RNA - Peritubular cells [nTPM]":"28.2","Single Cell Type RNA - Plasma cells [nTPM]":"1.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.7","Single Cell Type RNA - Sertoli cells [nTPM]":"78.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"49.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"73.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"3.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"46.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"33.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"32.7","Single Cell Type RNA - T-cells [nTPM]":"1.6","Single Cell Type RNA - Theca cells [nTPM]":"3.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.2","Single Cell Type RNA - Urothelial cells [nTPM]":"7.4"},{"Gene":"SNRPE","Gene synonym":["Sm-E"],"Ensembl":"ENSG00000182004","Gene description":"Small nuclear ribonucleoprotein polypeptide E","Uniprot":["P62304"],"Chromosome":"1","Position":"203861599-203871152","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":["Ribonucleoprotein","RNA-binding"],"Disease involvement":["Disease variant","Hypotrichosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"34000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 32: Non-specific - Translation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.95e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.38e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-3"},"Tissue RNA - adipose tissue [nTPM]":"36.5","Tissue RNA - adrenal gland [nTPM]":"50.0","Tissue RNA - amygdala [nTPM]":"37.5","Tissue RNA - appendix [nTPM]":"50.4","Tissue RNA - basal ganglia [nTPM]":"39.6","Tissue RNA - bone marrow [nTPM]":"87.2","Tissue RNA - breast [nTPM]":"65.7","Tissue RNA - cerebellum [nTPM]":"43.3","Tissue RNA - cerebral cortex [nTPM]":"61.3","Tissue RNA - cervix [nTPM]":"41.4","Tissue RNA - choroid plexus [nTPM]":"43.9","Tissue RNA - colon [nTPM]":"52.5","Tissue RNA - duodenum [nTPM]":"31.8","Tissue RNA - endometrium 1 [nTPM]":"42.4","Tissue RNA - epididymis [nTPM]":"59.5","Tissue RNA - esophagus [nTPM]":"39.1","Tissue RNA - fallopian tube [nTPM]":"38.5","Tissue RNA - gallbladder [nTPM]":"24.1","Tissue RNA - heart muscle [nTPM]":"34.5","Tissue RNA - hippocampal formation [nTPM]":"38.2","Tissue RNA - hypothalamus [nTPM]":"41.2","Tissue RNA - kidney [nTPM]":"47.3","Tissue RNA - liver [nTPM]":"46.1","Tissue RNA - lung [nTPM]":"25.6","Tissue RNA - lymph node [nTPM]":"50.0","Tissue RNA - medulla oblongata [nTPM]":"38.0","Tissue RNA - midbrain [nTPM]":"39.8","Tissue RNA - ovary [nTPM]":"64.7","Tissue RNA - pancreas [nTPM]":"38.0","Tissue RNA - parathyroid gland [nTPM]":"37.6","Tissue RNA - pituitary gland [nTPM]":"24.9","Tissue RNA - placenta [nTPM]":"39.3","Tissue RNA - pons [nTPM]":"40.5","Tissue RNA - prostate [nTPM]":"29.6","Tissue RNA - rectum [nTPM]":"41.5","Tissue RNA - retina [nTPM]":"37.8","Tissue RNA - salivary gland [nTPM]":"33.0","Tissue RNA - seminal vesicle [nTPM]":"29.2","Tissue RNA - skeletal muscle [nTPM]":"39.9","Tissue RNA - skin 1 [nTPM]":"31.0","Tissue RNA - small intestine [nTPM]":"33.9","Tissue RNA - smooth muscle [nTPM]":"27.2","Tissue RNA - spinal cord [nTPM]":"41.1","Tissue RNA - spleen [nTPM]":"33.3","Tissue RNA - stomach 1 [nTPM]":"35.7","Tissue RNA - testis [nTPM]":"22.4","Tissue RNA - thalamus [nTPM]":"38.0","Tissue RNA - thymus [nTPM]":"100.4","Tissue RNA - thyroid gland [nTPM]":"27.8","Tissue RNA - tongue [nTPM]":"22.3","Tissue RNA - tonsil [nTPM]":"58.2","Tissue RNA - urinary bladder [nTPM]":"51.4","Tissue RNA - vagina [nTPM]":"33.9","Tissue RNA - white matter [nTPM]":"43.4","Cell RNA - A-431 [nTPM]":"262.9","Cell RNA - A549 [nTPM]":"85.4","Cell RNA - AF22 [nTPM]":"307.0","Cell RNA - AN3-CA [nTPM]":"157.4","Cell RNA - ASC diff [nTPM]":"64.6","Cell RNA - ASC TERT1 [nTPM]":"131.4","Cell RNA - BEWO [nTPM]":"179.1","Cell RNA - BJ [nTPM]":"187.1","Cell RNA - BJ hTERT+ [nTPM]":"111.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"159.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"147.5","Cell RNA - CACO-2 [nTPM]":"103.1","Cell RNA - CAPAN-2 [nTPM]":"200.6","Cell RNA - Daudi [nTPM]":"258.4","Cell RNA - EFO-21 [nTPM]":"154.3","Cell RNA - fHDF\/TERT166 [nTPM]":"111.9","Cell RNA - GAMG [nTPM]":"164.0","Cell RNA - HaCaT [nTPM]":"185.7","Cell RNA - HAP1 [nTPM]":"258.1","Cell RNA - HBEC3-KT [nTPM]":"206.8","Cell RNA - HBF TERT88 [nTPM]":"205.2","Cell RNA - HDLM-2 [nTPM]":"105.1","Cell RNA - HEK 293 [nTPM]":"120.4","Cell RNA - HEL [nTPM]":"166.4","Cell RNA - HeLa [nTPM]":"169.8","Cell RNA - Hep G2 [nTPM]":"144.5","Cell RNA - HHSteC [nTPM]":"106.8","Cell RNA - HL-60 [nTPM]":"375.6","Cell RNA - HMC-1 [nTPM]":"168.1","Cell RNA - HSkMC [nTPM]":"113.7","Cell RNA - hTCEpi [nTPM]":"55.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"190.1","Cell RNA - hTERT-HME1 [nTPM]":"176.1","Cell RNA - hTERT-RPE1 [nTPM]":"151.4","Cell RNA - HUVEC TERT2 [nTPM]":"146.4","Cell RNA - JURKAT [nTPM]":"288.3","Cell RNA - K-562 [nTPM]":"310.0","Cell RNA - Karpas-707 [nTPM]":"155.7","Cell RNA - LHCN-M2 [nTPM]":"138.9","Cell RNA - MCF7 [nTPM]":"150.7","Cell RNA - MOLT-4 [nTPM]":"372.6","Cell RNA - NB-4 [nTPM]":"360.0","Cell RNA - NTERA-2 [nTPM]":"413.1","Cell RNA - OE19 [nTPM]":"175.6","Cell RNA - PC-3 [nTPM]":"91.4","Cell RNA - REH [nTPM]":"242.9","Cell RNA - RH-30 [nTPM]":"295.0","Cell RNA - RPMI-8226 [nTPM]":"303.9","Cell RNA - RPTEC TERT1 [nTPM]":"201.5","Cell RNA - RT4 [nTPM]":"96.1","Cell RNA - SCLC-21H [nTPM]":"160.9","Cell RNA - SH-SY5Y [nTPM]":"210.2","Cell RNA - SiHa [nTPM]":"130.5","Cell RNA - SK-BR-3 [nTPM]":"275.7","Cell RNA - SK-MEL-30 [nTPM]":"347.6","Cell RNA - SuSa [nTPM]":"271.2","Cell RNA - T-47d [nTPM]":"203.7","Cell RNA - THP-1 [nTPM]":"261.7","Cell RNA - TIME [nTPM]":"98.4","Cell RNA - U-138 MG [nTPM]":"127.6","Cell RNA - U-2 OS [nTPM]":"216.4","Cell RNA - U-2197 [nTPM]":"115.9","Cell RNA - U-251 MG [nTPM]":"341.7","Cell RNA - U-266\/70 [nTPM]":"130.7","Cell RNA - U-266\/84 [nTPM]":"184.3","Cell RNA - U-698 [nTPM]":"574.1","Cell RNA - U-87 MG [nTPM]":"125.6","Cell RNA - U-937 [nTPM]":"198.3","Cell RNA - WM-115 [nTPM]":"146.9","Blood RNA - basophil [nTPM]":"14.6","Blood RNA - classical monocyte [nTPM]":"22.6","Blood RNA - eosinophil [nTPM]":"13.7","Blood RNA - gdT-cell [nTPM]":"19.7","Blood RNA - intermediate monocyte [nTPM]":"21.1","Blood RNA - MAIT T-cell [nTPM]":"30.2","Blood RNA - memory B-cell [nTPM]":"24.0","Blood RNA - memory CD4 T-cell [nTPM]":"26.7","Blood RNA - memory CD8 T-cell [nTPM]":"20.9","Blood RNA - myeloid DC [nTPM]":"34.1","Blood RNA - naive B-cell [nTPM]":"21.5","Blood RNA - naive CD4 T-cell [nTPM]":"26.7","Blood RNA - naive CD8 T-cell [nTPM]":"26.3","Blood RNA - neutrophil [nTPM]":"7.4","Blood RNA - NK-cell [nTPM]":"37.0","Blood RNA - non-classical monocyte [nTPM]":"25.4","Blood RNA - plasmacytoid DC [nTPM]":"46.0","Blood RNA - T-reg [nTPM]":"23.1","Blood RNA - total PBMC [nTPM]":"19.1","Brain RNA - amygdala [nTPM]":"37.5","Brain RNA - basal ganglia [nTPM]":"39.6","Brain RNA - cerebellum [nTPM]":"43.3","Brain RNA - cerebral cortex [nTPM]":"61.3","Brain RNA - hippocampal formation [nTPM]":"38.2","Brain RNA - hypothalamus [nTPM]":"41.2","Brain RNA - medulla oblongata [nTPM]":"38.0","Brain RNA - midbrain [nTPM]":"39.8","Brain RNA - pons [nTPM]":"40.5","Brain RNA - spinal cord [nTPM]":"41.1","Brain RNA - thalamus [nTPM]":"38.0","Brain RNA - white matter [nTPM]":"43.4","Single Cell Type RNA - Adipocytes [nTPM]":"125.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"128.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"116.4","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"153.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"244.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"284.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"442.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"101.3","Single Cell Type RNA - Bipolar cells [nTPM]":"48.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"190.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"204.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"73.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"204.5","Single Cell Type RNA - Club cells [nTPM]":"226.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"128.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"454.6","Single Cell Type RNA - dendritic cells [nTPM]":"146.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"92.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"424.6","Single Cell Type RNA - Ductal cells [nTPM]":"408.6","Single Cell Type RNA - Early spermatids [nTPM]":"23.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"179.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"197.6","Single Cell Type RNA - Endothelial cells [nTPM]":"173.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"163.4","Single Cell Type RNA - Erythroid cells [nTPM]":"176.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"473.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"612.3","Single Cell Type RNA - Fibroblasts [nTPM]":"159.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"72.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"188.6","Single Cell Type RNA - granulocytes [nTPM]":"112.7","Single Cell Type RNA - Granulosa cells [nTPM]":"190.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"138.5","Single Cell Type RNA - Hepatocytes [nTPM]":"278.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"300.7","Single Cell Type RNA - Horizontal cells [nTPM]":"57.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"241.2","Single Cell Type RNA - Ionocytes [nTPM]":"341.8","Single Cell Type RNA - Kupffer cells [nTPM]":"172.9","Single Cell Type RNA - Langerhans cells [nTPM]":"177.6","Single Cell Type RNA - Late spermatids [nTPM]":"34.8","Single Cell Type RNA - Leydig cells [nTPM]":"237.0","Single Cell Type RNA - Macrophages [nTPM]":"117.6","Single Cell Type RNA - Melanocytes [nTPM]":"172.5","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"304.5","Single Cell Type RNA - Muller glia cells [nTPM]":"149.7","Single Cell Type RNA - NK-cells [nTPM]":"212.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"421.8","Single Cell Type RNA - Paneth cells [nTPM]":"136.7","Single Cell Type RNA - Peritubular cells [nTPM]":"164.0","Single Cell Type RNA - Plasma cells [nTPM]":"97.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"351.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"113.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"434.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"162.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"48.3","Single Cell Type RNA - Sertoli cells [nTPM]":"98.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"272.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"240.4","Single Cell Type RNA - Spermatocytes [nTPM]":"217.7","Single Cell Type RNA - Spermatogonia [nTPM]":"239.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"128.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"256.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"225.1","Single Cell Type RNA - T-cells [nTPM]":"126.2","Single Cell Type RNA - Theca cells [nTPM]":"178.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"313.8","Single Cell Type RNA - Urothelial cells [nTPM]":"294.1"},{"Gene":"SPINK5","Gene synonym":["DKFZp686K19184","FLJ21544","FLJ97536","FLJ97596","FLJ99794","LEKTI","LETKI","NETS","NS","VAKTI"],"Ensembl":"ENSG00000133710","Gene description":"Serine peptidase inhibitor Kazal type 5","Uniprot":["Q9NQ38"],"Chromosome":"5","Position":"148025683-148137382","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Protease inhibitor","Serine protease inhibitor"],"Disease involvement":["Hypotrichosis","Ichthyosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"338.5","esophagus":"1015.0","skin 1":"318.2","vagina":"582.6"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Squamous epithelial cells":"1622.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"45.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"14.7","HeLa":"22.7","Karpas-707":"19.3","SuSa":"6.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009067","HPA011351","CAB015347"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Vesicles"],"Secretome location":"Secreted in other tissues","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"43000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 61: Squamous epithelial cells - Keratinization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB015347":"AB_2196138","HPA009067":"AB_1080084","HPA011351":"AB_1857447"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.85e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.1","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"17.5","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"338.5","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"4.8","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.6","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"1015.0","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"1.8","Tissue RNA - heart muscle [nTPM]":"1.7","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.8","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"2.0","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"1.0","Tissue RNA - pituitary gland [nTPM]":"2.0","Tissue RNA - placenta [nTPM]":"2.4","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"1.3","Tissue RNA - rectum [nTPM]":"10.6","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"145.0","Tissue RNA - seminal vesicle [nTPM]":"0.5","Tissue RNA - skeletal muscle [nTPM]":"1.8","Tissue RNA - skin 1 [nTPM]":"318.2","Tissue RNA - small intestine [nTPM]":"0.6","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"5.0","Tissue RNA - testis [nTPM]":"1.6","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"9.1","Tissue RNA - thyroid gland [nTPM]":"2.2","Tissue RNA - tongue [nTPM]":"1.1","Tissue RNA - tonsil [nTPM]":"292.9","Tissue RNA - urinary bladder [nTPM]":"0.7","Tissue RNA - vagina [nTPM]":"582.6","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.8","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"1.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"14.7","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"1.3","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"22.7","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"3.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.9","Cell RNA - Karpas-707 [nTPM]":"19.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"2.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"2.6","Cell RNA - OE19 [nTPM]":"2.0","Cell RNA - PC-3 [nTPM]":"0.3","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"5.7","Cell RNA - SCLC-21H [nTPM]":"2.8","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.6","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"6.6","Cell RNA - T-47d [nTPM]":"4.6","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"5.0","Cell RNA - U-266\/84 [nTPM]":"2.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"5.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"45.4","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"53.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"331.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"102.4","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"115.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"177.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"11.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"12.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.1","Single Cell Type RNA - Fibroblasts [nTPM]":"2.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.8","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"33.8","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"2.1","Single Cell Type RNA - Late spermatids [nTPM]":"3.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.6","Single Cell Type RNA - Paneth cells [nTPM]":"60.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"3.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.4","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"4.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1622.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"64.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"1.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"97.9","Single Cell Type RNA - Urothelial cells [nTPM]":"2.7"},{"Gene":"STAT4","Gene synonym":[],"Ensembl":"ENSG00000138378","Gene description":"Signal transducer and activator of transcription 4","Uniprot":["Q14765"],"Chromosome":"2","Position":"191029576-191151596","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Cancer-related genes","Systemic lupus erythematosus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"23.0","testis":"29.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"139.0","Early spermatids":"275.1","Excitatory neurons":"85.9","Late spermatids":"66.0","NK-cells":"108.1","Plasma cells":"83.8","T-cells":"137.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"NK-cells":"76.6","T-cells":"121.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"58.8","U-266\/70":"32.9","U-266\/84":"12.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001860","CAB013108"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB013108":null,"HPA001860":"AB_1080104"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.45e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.88e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.07e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.02e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Tissue RNA - adipose tissue [nTPM]":"4.7","Tissue RNA - adrenal gland [nTPM]":"4.0","Tissue RNA - amygdala [nTPM]":"3.4","Tissue RNA - appendix [nTPM]":"11.5","Tissue RNA - basal ganglia [nTPM]":"4.4","Tissue RNA - bone marrow [nTPM]":"15.7","Tissue RNA - breast [nTPM]":"3.0","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"10.4","Tissue RNA - cervix [nTPM]":"1.6","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"2.8","Tissue RNA - duodenum [nTPM]":"4.5","Tissue RNA - endometrium 1 [nTPM]":"1.9","Tissue RNA - epididymis [nTPM]":"2.6","Tissue RNA - esophagus [nTPM]":"1.4","Tissue RNA - fallopian tube [nTPM]":"1.6","Tissue RNA - gallbladder [nTPM]":"5.1","Tissue RNA - heart muscle [nTPM]":"23.0","Tissue RNA - hippocampal formation [nTPM]":"3.8","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"4.5","Tissue RNA - liver [nTPM]":"9.5","Tissue RNA - lung [nTPM]":"7.8","Tissue RNA - lymph node [nTPM]":"18.0","Tissue RNA - medulla oblongata [nTPM]":"2.1","Tissue RNA - midbrain [nTPM]":"1.7","Tissue RNA - ovary [nTPM]":"1.5","Tissue RNA - pancreas [nTPM]":"2.2","Tissue RNA - parathyroid gland [nTPM]":"1.2","Tissue RNA - pituitary gland [nTPM]":"15.0","Tissue RNA - placenta [nTPM]":"2.6","Tissue RNA - pons [nTPM]":"2.0","Tissue RNA - prostate [nTPM]":"1.8","Tissue RNA - rectum [nTPM]":"3.4","Tissue RNA - retina [nTPM]":"2.1","Tissue RNA - salivary gland [nTPM]":"2.2","Tissue RNA - seminal vesicle [nTPM]":"1.3","Tissue RNA - skeletal muscle [nTPM]":"1.2","Tissue RNA - skin 1 [nTPM]":"1.1","Tissue RNA - small intestine [nTPM]":"6.9","Tissue RNA - smooth muscle [nTPM]":"1.4","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"15.5","Tissue RNA - stomach 1 [nTPM]":"4.4","Tissue RNA - testis [nTPM]":"29.2","Tissue RNA - thalamus [nTPM]":"3.4","Tissue RNA - thymus [nTPM]":"9.0","Tissue RNA - thyroid gland [nTPM]":"2.4","Tissue RNA - tongue [nTPM]":"1.0","Tissue RNA - tonsil [nTPM]":"10.4","Tissue RNA - urinary bladder [nTPM]":"5.9","Tissue RNA - vagina [nTPM]":"1.8","Tissue RNA - white matter [nTPM]":"4.5","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"1.7","Cell RNA - AF22 [nTPM]":"1.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"3.6","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"0.6","Cell RNA - BJ hTERT+ [nTPM]":"2.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.2","Cell RNA - CACO-2 [nTPM]":"0.4","Cell RNA - CAPAN-2 [nTPM]":"0.8","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"2.8","Cell RNA - GAMG [nTPM]":"1.6","Cell RNA - HaCaT [nTPM]":"0.9","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"4.7","Cell RNA - HBF TERT88 [nTPM]":"1.2","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.8","Cell RNA - HEL [nTPM]":"1.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.6","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"1.5","Cell RNA - hTCEpi [nTPM]":"2.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.1","Cell RNA - hTERT-HME1 [nTPM]":"0.5","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"6.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"58.8","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"3.5","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.9","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"4.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"1.2","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"1.6","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"32.9","Cell RNA - U-266\/84 [nTPM]":"12.8","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"15.7","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"121.2","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"107.3","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"71.6","Blood RNA - memory CD8 T-cell [nTPM]":"101.2","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"68.1","Blood RNA - naive CD8 T-cell [nTPM]":"95.8","Blood RNA - neutrophil [nTPM]":"2.8","Blood RNA - NK-cell [nTPM]":"76.6","Blood RNA - non-classical monocyte [nTPM]":"0.8","Blood RNA - plasmacytoid DC [nTPM]":"9.3","Blood RNA - T-reg [nTPM]":"28.1","Blood RNA - total PBMC [nTPM]":"55.3","Brain RNA - amygdala [nTPM]":"3.4","Brain RNA - basal ganglia [nTPM]":"4.4","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"10.4","Brain RNA - hippocampal formation [nTPM]":"3.8","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"2.1","Brain RNA - midbrain [nTPM]":"1.7","Brain RNA - pons [nTPM]":"2.0","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"3.4","Brain RNA - white matter [nTPM]":"4.5","Single Cell Type RNA - Adipocytes [nTPM]":"2.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.2","Single Cell Type RNA - Astrocytes [nTPM]":"2.6","Single Cell Type RNA - B-cells [nTPM]":"14.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"139.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.6","Single Cell Type RNA - Early spermatids [nTPM]":"275.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"1.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"10.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"85.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.9","Single Cell Type RNA - Fibroblasts [nTPM]":"2.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"1.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"59.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"6.3","Single Cell Type RNA - Langerhans cells [nTPM]":"10.6","Single Cell Type RNA - Late spermatids [nTPM]":"66.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"14.4","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"6.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"108.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"83.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.7","Single Cell Type RNA - Spermatocytes [nTPM]":"8.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"137.4","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"SUFU","Gene synonym":["PRO1280","SUFUH","SUFUXL"],"Ensembl":"ENSG00000107882","Gene description":"SUFU negative regulator of hedgehog signaling","Uniprot":["Q9UMX1"],"Chromosome":"10","Position":"102503972-102633535","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":["Cancer-related genes","Ciliopathy","Disease variant","Joubert syndrome","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"129.2","Late spermatids":"115.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008700"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 23: AN3-CA - Transcription regulation","Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA008700":"AB_1080125"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-3"},"Tissue RNA - adipose tissue [nTPM]":"6.6","Tissue RNA - adrenal gland [nTPM]":"7.2","Tissue RNA - amygdala [nTPM]":"8.8","Tissue RNA - appendix [nTPM]":"7.1","Tissue RNA - basal ganglia [nTPM]":"8.5","Tissue RNA - bone marrow [nTPM]":"2.0","Tissue RNA - breast [nTPM]":"6.1","Tissue RNA - cerebellum [nTPM]":"8.9","Tissue RNA - cerebral cortex [nTPM]":"8.0","Tissue RNA - cervix [nTPM]":"8.6","Tissue RNA - choroid plexus [nTPM]":"5.5","Tissue RNA - colon [nTPM]":"6.8","Tissue RNA - duodenum [nTPM]":"3.9","Tissue RNA - endometrium 1 [nTPM]":"7.4","Tissue RNA - epididymis [nTPM]":"4.9","Tissue RNA - esophagus [nTPM]":"9.2","Tissue RNA - fallopian tube [nTPM]":"7.1","Tissue RNA - gallbladder [nTPM]":"6.6","Tissue RNA - heart muscle [nTPM]":"6.3","Tissue RNA - hippocampal formation [nTPM]":"7.8","Tissue RNA - hypothalamus [nTPM]":"7.3","Tissue RNA - kidney [nTPM]":"6.1","Tissue RNA - liver [nTPM]":"6.2","Tissue RNA - lung [nTPM]":"5.8","Tissue RNA - lymph node [nTPM]":"7.2","Tissue RNA - medulla oblongata [nTPM]":"8.3","Tissue RNA - midbrain [nTPM]":"8.2","Tissue RNA - ovary [nTPM]":"8.9","Tissue RNA - pancreas [nTPM]":"4.1","Tissue RNA - parathyroid gland [nTPM]":"11.1","Tissue RNA - pituitary gland [nTPM]":"4.3","Tissue RNA - placenta [nTPM]":"7.4","Tissue RNA - pons [nTPM]":"7.8","Tissue RNA - prostate [nTPM]":"8.5","Tissue RNA - rectum [nTPM]":"4.4","Tissue RNA - retina [nTPM]":"4.6","Tissue RNA - salivary gland [nTPM]":"7.1","Tissue RNA - seminal vesicle [nTPM]":"5.2","Tissue RNA - skeletal muscle [nTPM]":"8.6","Tissue RNA - skin 1 [nTPM]":"14.4","Tissue RNA - small intestine [nTPM]":"5.7","Tissue RNA - smooth muscle [nTPM]":"7.3","Tissue RNA - spinal cord [nTPM]":"6.7","Tissue RNA - spleen [nTPM]":"7.4","Tissue RNA - stomach 1 [nTPM]":"4.6","Tissue RNA - testis [nTPM]":"11.5","Tissue RNA - thalamus [nTPM]":"8.0","Tissue RNA - thymus [nTPM]":"7.8","Tissue RNA - thyroid gland [nTPM]":"3.4","Tissue RNA - tongue [nTPM]":"7.3","Tissue RNA - tonsil [nTPM]":"8.1","Tissue RNA - urinary bladder [nTPM]":"8.8","Tissue RNA - vagina [nTPM]":"9.2","Tissue RNA - white matter [nTPM]":"7.3","Cell RNA - A-431 [nTPM]":"8.7","Cell RNA - A549 [nTPM]":"9.1","Cell RNA - AF22 [nTPM]":"14.4","Cell RNA - AN3-CA [nTPM]":"20.8","Cell RNA - ASC diff [nTPM]":"14.5","Cell RNA - ASC TERT1 [nTPM]":"12.1","Cell RNA - BEWO [nTPM]":"7.0","Cell RNA - BJ [nTPM]":"8.8","Cell RNA - BJ hTERT+ [nTPM]":"17.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.3","Cell RNA - CACO-2 [nTPM]":"8.5","Cell RNA - CAPAN-2 [nTPM]":"6.3","Cell RNA - Daudi [nTPM]":"8.9","Cell RNA - EFO-21 [nTPM]":"24.5","Cell RNA - fHDF\/TERT166 [nTPM]":"9.9","Cell RNA - GAMG [nTPM]":"5.0","Cell RNA - HaCaT [nTPM]":"6.0","Cell RNA - HAP1 [nTPM]":"17.8","Cell RNA - HBEC3-KT [nTPM]":"9.8","Cell RNA - HBF TERT88 [nTPM]":"8.2","Cell RNA - HDLM-2 [nTPM]":"5.5","Cell RNA - HEK 293 [nTPM]":"13.8","Cell RNA - HEL [nTPM]":"21.2","Cell RNA - HeLa [nTPM]":"5.2","Cell RNA - Hep G2 [nTPM]":"8.0","Cell RNA - HHSteC [nTPM]":"6.9","Cell RNA - HL-60 [nTPM]":"7.7","Cell RNA - HMC-1 [nTPM]":"14.6","Cell RNA - HSkMC [nTPM]":"13.9","Cell RNA - hTCEpi [nTPM]":"7.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.3","Cell RNA - hTERT-HME1 [nTPM]":"7.5","Cell RNA - hTERT-RPE1 [nTPM]":"22.9","Cell RNA - HUVEC TERT2 [nTPM]":"16.3","Cell RNA - JURKAT [nTPM]":"8.5","Cell RNA - K-562 [nTPM]":"4.8","Cell RNA - Karpas-707 [nTPM]":"7.9","Cell RNA - LHCN-M2 [nTPM]":"7.8","Cell RNA - MCF7 [nTPM]":"7.2","Cell RNA - MOLT-4 [nTPM]":"14.8","Cell RNA - NB-4 [nTPM]":"11.6","Cell RNA - NTERA-2 [nTPM]":"4.1","Cell RNA - OE19 [nTPM]":"5.6","Cell RNA - PC-3 [nTPM]":"6.7","Cell RNA - REH [nTPM]":"15.8","Cell RNA - RH-30 [nTPM]":"15.5","Cell RNA - RPMI-8226 [nTPM]":"4.7","Cell RNA - RPTEC TERT1 [nTPM]":"8.3","Cell RNA - RT4 [nTPM]":"12.8","Cell RNA - SCLC-21H [nTPM]":"4.8","Cell RNA - SH-SY5Y [nTPM]":"7.8","Cell RNA - SiHa [nTPM]":"7.0","Cell RNA - SK-BR-3 [nTPM]":"6.4","Cell RNA - SK-MEL-30 [nTPM]":"8.1","Cell RNA - SuSa [nTPM]":"13.1","Cell RNA - T-47d [nTPM]":"14.2","Cell RNA - THP-1 [nTPM]":"5.0","Cell RNA - TIME [nTPM]":"18.1","Cell RNA - U-138 MG [nTPM]":"5.5","Cell RNA - U-2 OS [nTPM]":"7.8","Cell RNA - U-2197 [nTPM]":"6.0","Cell RNA - U-251 MG [nTPM]":"9.8","Cell RNA - U-266\/70 [nTPM]":"6.4","Cell RNA - U-266\/84 [nTPM]":"4.5","Cell RNA - U-698 [nTPM]":"6.4","Cell RNA - U-87 MG [nTPM]":"6.9","Cell RNA - U-937 [nTPM]":"14.9","Cell RNA - WM-115 [nTPM]":"3.8","Blood RNA - basophil [nTPM]":"2.0","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"2.9","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"2.4","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"1.9","Blood RNA - naive B-cell [nTPM]":"0.8","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"2.5","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"8.8","Brain RNA - basal ganglia [nTPM]":"8.5","Brain RNA - cerebellum [nTPM]":"8.9","Brain RNA - cerebral cortex [nTPM]":"8.0","Brain RNA - hippocampal formation [nTPM]":"7.8","Brain RNA - hypothalamus [nTPM]":"7.3","Brain RNA - medulla oblongata [nTPM]":"8.3","Brain RNA - midbrain [nTPM]":"8.2","Brain RNA - pons [nTPM]":"7.8","Brain RNA - spinal cord [nTPM]":"6.7","Brain RNA - thalamus [nTPM]":"8.0","Brain RNA - white matter [nTPM]":"7.3","Single Cell Type RNA - Adipocytes [nTPM]":"3.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.7","Single Cell Type RNA - Astrocytes [nTPM]":"28.7","Single Cell Type RNA - B-cells [nTPM]":"4.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"4.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"4.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.8","Single Cell Type RNA - dendritic cells [nTPM]":"3.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.4","Single Cell Type RNA - Early spermatids [nTPM]":"129.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.2","Single Cell Type RNA - Endothelial cells [nTPM]":"5.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.5","Single Cell Type RNA - Fibroblasts [nTPM]":"6.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.5","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"3.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.8","Single Cell Type RNA - Hepatocytes [nTPM]":"5.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.4","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"9.4","Single Cell Type RNA - Langerhans cells [nTPM]":"6.3","Single Cell Type RNA - Late spermatids [nTPM]":"115.9","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"8.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"32.8","Single Cell Type RNA - monocytes [nTPM]":"7.8","Single Cell Type RNA - Muller glia cells [nTPM]":"2.7","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.1","Single Cell Type RNA - Paneth cells [nTPM]":"1.3","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"4.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.5","Single Cell Type RNA - Spermatocytes [nTPM]":"8.7","Single Cell Type RNA - Spermatogonia [nTPM]":"5.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.0","Single Cell Type RNA - T-cells [nTPM]":"7.1","Single Cell Type RNA - Theca cells [nTPM]":"7.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"TCHH","Gene synonym":["THH"],"Ensembl":"ENSG00000159450","Gene description":"Trichohyalin","Uniprot":["Q07283"],"Chromosome":"1","Position":"152106317-152115454","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Keratinization"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"19","RNA tissue specific nTPM":{"skin 1":"41.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"26.2","Langerhans cells":"9.5","Macrophages":"21.8","Spermatocytes":"22.6","Spermatogonia":"29.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"2.8"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"3.6","SCLC-21H":"1.1","THP-1":"2.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028375"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Skin - Cornification","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA028375":"AB_10601722"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.97e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.12e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.55e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.28e-7"},"Tissue RNA - adipose tissue [nTPM]":"0.7","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.2","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"1.1","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"41.4","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"2.2","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.6","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"3.6","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"1.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"1.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.9","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"2.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"1.0","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.2","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"5.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"6.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"3.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.5","Single Cell Type RNA - Fibroblasts [nTPM]":"0.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"26.2","Single Cell Type RNA - Langerhans cells [nTPM]":"9.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"21.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"3.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.4","Single Cell Type RNA - Spermatocytes [nTPM]":"22.6","Single Cell Type RNA - Spermatogonia [nTPM]":"29.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.2","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"TGM3","Gene synonym":["TGE"],"Ensembl":"ENSG00000125780","Gene description":"Transglutaminase 3","Uniprot":["Q08188"],"Chromosome":"20","Position":"2296001-2341079","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Keratinization"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"esophagus":"1838.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Enteroendocrine cells":"46.2","Squamous epithelial cells":"22.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"9","RNA cancer specific FPKM":{"head and neck cancer":"81.6"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"295","RNA blood cell specific nTPM":{"neutrophil":"30.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"303","RNA blood lineage specific nTPM":{"granulocytes":"30.3"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"14","RNA cell line specific nTPM":{"EFO-21":"5.2"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004728"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"14000000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 61: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA004728":"AB_1080360"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.88e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.78e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.67e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.6","Tissue RNA - adrenal gland [nTPM]":"0.3","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"1.4","Tissue RNA - breast [nTPM]":"3.9","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"54.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"1838.1","Tissue RNA - fallopian tube [nTPM]":"1.4","Tissue RNA - gallbladder [nTPM]":"2.2","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.8","Tissue RNA - lung [nTPM]":"0.5","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.3","Tissue RNA - pancreas [nTPM]":"1.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.6","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.6","Tissue RNA - rectum [nTPM]":"0.8","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"229.3","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"83.1","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"2.2","Tissue RNA - testis [nTPM]":"2.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"142.9","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"31.4","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"5.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"30.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"46.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"4.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"TLR2","Gene synonym":["CD282","TIL4"],"Ensembl":"ENSG00000137462","Gene description":"Toll like receptor 2","Uniprot":["O60603"],"Chromosome":"4","Position":"153684070-153706260","Protein class":["CD markers","Enzymes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Hydrolase","Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"69.9","lymphoid tissue":"51.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"77.3","Kupffer cells":"117.2","Langerhans cells":"35.7","Macrophages":"101.8","Microglial cells":"33.7","monocytes":"68.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"199.6","intermediate monocyte":"178.9","myeloid DC":"121.3","neutrophil":"457.8","non-classical monocyte":"121.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"49","RNA blood lineage specific nTPM":{"dendritic cells":"121.3","granulocytes":"457.8","monocytes":"199.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HL-60":"11.6","HSkMC":"12.5","hTCEpi":"12.7","NB-4":"11.4","RPTEC TERT1":"13.3","RT4":"16.3","THP-1":"62.0","U-937":"11.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA060231","HPA071546"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA060231":null,"HPA071546":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.11e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.93e-3"},"Tissue RNA - adipose tissue [nTPM]":"26.8","Tissue RNA - adrenal gland [nTPM]":"11.8","Tissue RNA - amygdala [nTPM]":"4.3","Tissue RNA - appendix [nTPM]":"51.7","Tissue RNA - basal ganglia [nTPM]":"4.4","Tissue RNA - bone marrow [nTPM]":"69.9","Tissue RNA - breast [nTPM]":"12.5","Tissue RNA - cerebellum [nTPM]":"4.6","Tissue RNA - cerebral cortex [nTPM]":"7.5","Tissue RNA - cervix [nTPM]":"7.9","Tissue RNA - choroid plexus [nTPM]":"7.6","Tissue RNA - colon [nTPM]":"4.6","Tissue RNA - duodenum [nTPM]":"3.9","Tissue RNA - endometrium 1 [nTPM]":"3.3","Tissue RNA - epididymis [nTPM]":"11.8","Tissue RNA - esophagus [nTPM]":"5.4","Tissue RNA - fallopian tube [nTPM]":"8.2","Tissue RNA - gallbladder [nTPM]":"16.3","Tissue RNA - heart muscle [nTPM]":"6.1","Tissue RNA - hippocampal formation [nTPM]":"4.0","Tissue RNA - hypothalamus [nTPM]":"5.3","Tissue RNA - kidney [nTPM]":"5.1","Tissue RNA - liver [nTPM]":"11.3","Tissue RNA - lung [nTPM]":"39.9","Tissue RNA - lymph node [nTPM]":"8.8","Tissue RNA - medulla oblongata [nTPM]":"9.5","Tissue RNA - midbrain [nTPM]":"5.9","Tissue RNA - ovary [nTPM]":"2.5","Tissue RNA - pancreas [nTPM]":"8.8","Tissue RNA - parathyroid gland [nTPM]":"3.4","Tissue RNA - pituitary gland [nTPM]":"4.0","Tissue RNA - placenta [nTPM]":"11.4","Tissue RNA - pons [nTPM]":"7.9","Tissue RNA - prostate [nTPM]":"4.7","Tissue RNA - rectum [nTPM]":"3.3","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"17.2","Tissue RNA - seminal vesicle [nTPM]":"12.3","Tissue RNA - skeletal muscle [nTPM]":"1.7","Tissue RNA - skin 1 [nTPM]":"3.5","Tissue RNA - small intestine [nTPM]":"4.9","Tissue RNA - smooth muscle [nTPM]":"11.7","Tissue RNA - spinal cord [nTPM]":"7.1","Tissue RNA - spleen [nTPM]":"35.9","Tissue RNA - stomach 1 [nTPM]":"5.2","Tissue RNA - testis [nTPM]":"1.9","Tissue RNA - thalamus [nTPM]":"7.4","Tissue RNA - thymus [nTPM]":"3.6","Tissue RNA - thyroid gland [nTPM]":"3.4","Tissue RNA - tongue [nTPM]":"3.7","Tissue RNA - tonsil [nTPM]":"15.4","Tissue RNA - urinary bladder [nTPM]":"23.6","Tissue RNA - vagina [nTPM]":"4.0","Tissue RNA - white matter [nTPM]":"10.1","Cell RNA - A-431 [nTPM]":"7.1","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"1.0","Cell RNA - ASC TERT1 [nTPM]":"2.9","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.8","Cell RNA - CACO-2 [nTPM]":"3.3","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"6.4","Cell RNA - HAP1 [nTPM]":"0.6","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.8","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"11.6","Cell RNA - HMC-1 [nTPM]":"0.9","Cell RNA - HSkMC [nTPM]":"12.5","Cell RNA - hTCEpi [nTPM]":"12.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"11.4","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"2.7","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"13.3","Cell RNA - RT4 [nTPM]":"16.3","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.7","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"3.3","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"62.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.7","Cell RNA - U-937 [nTPM]":"11.3","Cell RNA - WM-115 [nTPM]":"1.7","Blood RNA - basophil [nTPM]":"48.4","Blood RNA - classical monocyte [nTPM]":"199.6","Blood RNA - eosinophil [nTPM]":"1.8","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"178.9","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"121.3","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"457.8","Blood RNA - NK-cell [nTPM]":"5.3","Blood RNA - non-classical monocyte [nTPM]":"121.5","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"76.2","Brain RNA - amygdala [nTPM]":"4.3","Brain RNA - basal ganglia [nTPM]":"4.4","Brain RNA - cerebellum [nTPM]":"4.6","Brain RNA - cerebral cortex [nTPM]":"7.5","Brain RNA - hippocampal formation [nTPM]":"4.0","Brain RNA - hypothalamus [nTPM]":"5.3","Brain RNA - medulla oblongata [nTPM]":"9.5","Brain RNA - midbrain [nTPM]":"5.9","Brain RNA - pons [nTPM]":"7.9","Brain RNA - spinal cord [nTPM]":"7.1","Brain RNA - thalamus [nTPM]":"7.4","Brain RNA - white matter [nTPM]":"10.1","Single Cell Type RNA - Adipocytes [nTPM]":"1.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"77.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"19.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"2.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"1.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.9","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"1.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"17.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"117.2","Single Cell Type RNA - Langerhans cells [nTPM]":"35.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"101.8","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"33.7","Single Cell Type RNA - monocytes [nTPM]":"68.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.4","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"2.3","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.5","Single Cell Type RNA - Urothelial cells [nTPM]":"2.0"},{"Gene":"TLR9","Gene synonym":["CD289"],"Ensembl":"ENSG00000239732","Gene description":"Toll like receptor 9","Uniprot":["Q9NR96"],"Chromosome":"3","Position":"52221080-52225645","Protein class":["CD markers","FDA approved drug targets","Human disease related genes","Predicted membrane proteins"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Receptor"],"Disease involvement":["FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"6.1","lymphoid tissue":"6.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"B-cells":"3.3","Microglial cells":"1.0","Paneth cells":"1.1","Plasma cells":"1.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"plasmacytoid DC":"166.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"dendritic cells":"166.9"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Daudi":"53.5","RPMI-8226":"52.4","U-698":"27.6"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-7"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.91e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.9","Tissue RNA - appendix [nTPM]":"2.6","Tissue RNA - basal ganglia [nTPM]":"1.0","Tissue RNA - bone marrow [nTPM]":"1.3","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"2.2","Tissue RNA - cerebral cortex [nTPM]":"6.1","Tissue RNA - cervix [nTPM]":"1.2","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"0.9","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"0.7","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"0.6","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"1.1","Tissue RNA - hypothalamus [nTPM]":"0.8","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"0.6","Tissue RNA - lymph node [nTPM]":"6.0","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"1.0","Tissue RNA - ovary [nTPM]":"1.5","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"1.7","Tissue RNA - prostate [nTPM]":"0.7","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.7","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"1.2","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"1.3","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"3.0","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"0.9","Tissue RNA - thymus [nTPM]":"1.5","Tissue RNA - thyroid gland [nTPM]":"0.6","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"4.1","Tissue RNA - urinary bladder [nTPM]":"0.7","Tissue RNA - vagina [nTPM]":"0.8","Tissue RNA - white matter [nTPM]":"1.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.5","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"53.5","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.5","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.9","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"5.4","Cell RNA - NB-4 [nTPM]":"1.1","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"1.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"52.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"2.7","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"3.6","Cell RNA - U-266\/84 [nTPM]":"1.7","Cell RNA - U-698 [nTPM]":"27.6","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"2.5","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"2.7","Blood RNA - memory B-cell [nTPM]":"23.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"12.8","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"166.9","Blood RNA - T-reg [nTPM]":"2.5","Blood RNA - total PBMC [nTPM]":"1.8","Brain RNA - amygdala [nTPM]":"0.9","Brain RNA - basal ganglia [nTPM]":"1.0","Brain RNA - cerebellum [nTPM]":"2.2","Brain RNA - cerebral cortex [nTPM]":"6.1","Brain RNA - hippocampal formation [nTPM]":"1.1","Brain RNA - hypothalamus [nTPM]":"0.8","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"1.0","Brain RNA - pons [nTPM]":"1.7","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"0.9","Brain RNA - white matter [nTPM]":"1.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"3.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"1.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"TMC6","Gene synonym":["EVER1","EVIN1","LAK-4P","TNRC6C-AS1"],"Ensembl":"ENSG00000141524","Gene description":"Transmembrane channel like 6","Uniprot":["Q7Z403"],"Chromosome":"17","Position":"78107397-78132407","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"110.5"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"K-562":"108.7","SK-BR-3":"121.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051430"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051430":"AB_2681483"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.34e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.27e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.82e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.20e-4"},"Tissue RNA - adipose tissue [nTPM]":"29.5","Tissue RNA - adrenal gland [nTPM]":"6.8","Tissue RNA - amygdala [nTPM]":"19.2","Tissue RNA - appendix [nTPM]":"45.4","Tissue RNA - basal ganglia [nTPM]":"50.5","Tissue RNA - bone marrow [nTPM]":"72.7","Tissue RNA - breast [nTPM]":"25.2","Tissue RNA - cerebellum [nTPM]":"43.4","Tissue RNA - cerebral cortex [nTPM]":"33.5","Tissue RNA - cervix [nTPM]":"11.3","Tissue RNA - choroid plexus [nTPM]":"5.2","Tissue RNA - colon [nTPM]":"23.5","Tissue RNA - duodenum [nTPM]":"21.7","Tissue RNA - endometrium 1 [nTPM]":"7.6","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"25.4","Tissue RNA - fallopian tube [nTPM]":"14.1","Tissue RNA - gallbladder [nTPM]":"9.7","Tissue RNA - heart muscle [nTPM]":"35.9","Tissue RNA - hippocampal formation [nTPM]":"19.3","Tissue RNA - hypothalamus [nTPM]":"26.4","Tissue RNA - kidney [nTPM]":"20.6","Tissue RNA - liver [nTPM]":"9.1","Tissue RNA - lung [nTPM]":"40.3","Tissue RNA - lymph node [nTPM]":"69.7","Tissue RNA - medulla oblongata [nTPM]":"59.3","Tissue RNA - midbrain [nTPM]":"49.7","Tissue RNA - ovary [nTPM]":"3.8","Tissue RNA - pancreas [nTPM]":"14.6","Tissue RNA - parathyroid gland [nTPM]":"3.1","Tissue RNA - pituitary gland [nTPM]":"5.6","Tissue RNA - placenta [nTPM]":"8.8","Tissue RNA - pons [nTPM]":"55.9","Tissue RNA - prostate [nTPM]":"20.2","Tissue RNA - rectum [nTPM]":"6.6","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"29.3","Tissue RNA - seminal vesicle [nTPM]":"7.9","Tissue RNA - skeletal muscle [nTPM]":"3.5","Tissue RNA - skin 1 [nTPM]":"17.9","Tissue RNA - small intestine [nTPM]":"50.6","Tissue RNA - smooth muscle [nTPM]":"3.5","Tissue RNA - spinal cord [nTPM]":"35.8","Tissue RNA - spleen [nTPM]":"110.5","Tissue RNA - stomach 1 [nTPM]":"14.6","Tissue RNA - testis [nTPM]":"2.6","Tissue RNA - thalamus [nTPM]":"48.4","Tissue RNA - thymus [nTPM]":"26.3","Tissue RNA - thyroid gland [nTPM]":"12.9","Tissue RNA - tongue [nTPM]":"1.8","Tissue RNA - tonsil [nTPM]":"32.4","Tissue RNA - urinary bladder [nTPM]":"14.6","Tissue RNA - vagina [nTPM]":"18.4","Tissue RNA - white matter [nTPM]":"81.9","Cell RNA - A-431 [nTPM]":"17.9","Cell RNA - A549 [nTPM]":"14.0","Cell RNA - AF22 [nTPM]":"7.5","Cell RNA - AN3-CA [nTPM]":"6.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"15.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"25.2","Cell RNA - CAPAN-2 [nTPM]":"19.2","Cell RNA - Daudi [nTPM]":"19.7","Cell RNA - EFO-21 [nTPM]":"23.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"6.3","Cell RNA - HaCaT [nTPM]":"31.0","Cell RNA - HAP1 [nTPM]":"1.0","Cell RNA - HBEC3-KT [nTPM]":"5.9","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"2.0","Cell RNA - HEK 293 [nTPM]":"11.3","Cell RNA - HEL [nTPM]":"41.3","Cell RNA - HeLa [nTPM]":"4.2","Cell RNA - Hep G2 [nTPM]":"31.0","Cell RNA - HHSteC [nTPM]":"1.9","Cell RNA - HL-60 [nTPM]":"38.3","Cell RNA - HMC-1 [nTPM]":"67.0","Cell RNA - HSkMC [nTPM]":"1.1","Cell RNA - hTCEpi [nTPM]":"16.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"1.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.2","Cell RNA - HUVEC TERT2 [nTPM]":"14.7","Cell RNA - JURKAT [nTPM]":"9.2","Cell RNA - K-562 [nTPM]":"108.7","Cell RNA - Karpas-707 [nTPM]":"73.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"36.1","Cell RNA - MOLT-4 [nTPM]":"18.9","Cell RNA - NB-4 [nTPM]":"65.4","Cell RNA - NTERA-2 [nTPM]":"5.9","Cell RNA - OE19 [nTPM]":"32.9","Cell RNA - PC-3 [nTPM]":"4.9","Cell RNA - REH [nTPM]":"8.4","Cell RNA - RH-30 [nTPM]":"0.6","Cell RNA - RPMI-8226 [nTPM]":"58.9","Cell RNA - RPTEC TERT1 [nTPM]":"11.4","Cell RNA - RT4 [nTPM]":"65.1","Cell RNA - SCLC-21H [nTPM]":"1.9","Cell RNA - SH-SY5Y [nTPM]":"4.9","Cell RNA - SiHa [nTPM]":"5.7","Cell RNA - SK-BR-3 [nTPM]":"121.0","Cell RNA - SK-MEL-30 [nTPM]":"33.2","Cell RNA - SuSa [nTPM]":"9.7","Cell RNA - T-47d [nTPM]":"68.7","Cell RNA - THP-1 [nTPM]":"57.6","Cell RNA - TIME [nTPM]":"5.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"8.7","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"57.6","Cell RNA - U-266\/84 [nTPM]":"27.3","Cell RNA - U-698 [nTPM]":"13.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"60.4","Cell RNA - WM-115 [nTPM]":"1.0","Blood RNA - basophil [nTPM]":"17.7","Blood RNA - classical monocyte [nTPM]":"11.6","Blood RNA - eosinophil [nTPM]":"23.2","Blood RNA - gdT-cell [nTPM]":"56.2","Blood RNA - intermediate monocyte [nTPM]":"38.3","Blood RNA - MAIT T-cell [nTPM]":"49.0","Blood RNA - memory B-cell [nTPM]":"28.5","Blood RNA - memory CD4 T-cell [nTPM]":"41.7","Blood RNA - memory CD8 T-cell [nTPM]":"46.2","Blood RNA - myeloid DC [nTPM]":"18.6","Blood RNA - naive B-cell [nTPM]":"21.7","Blood RNA - naive CD4 T-cell [nTPM]":"36.5","Blood RNA - naive CD8 T-cell [nTPM]":"39.6","Blood RNA - neutrophil [nTPM]":"15.3","Blood RNA - NK-cell [nTPM]":"35.8","Blood RNA - non-classical monocyte [nTPM]":"63.5","Blood RNA - plasmacytoid DC [nTPM]":"5.7","Blood RNA - T-reg [nTPM]":"38.0","Blood RNA - total PBMC [nTPM]":"33.5","Brain RNA - amygdala [nTPM]":"19.2","Brain RNA - basal ganglia [nTPM]":"50.5","Brain RNA - cerebellum [nTPM]":"43.4","Brain RNA - cerebral cortex [nTPM]":"33.5","Brain RNA - hippocampal formation [nTPM]":"19.3","Brain RNA - hypothalamus [nTPM]":"26.4","Brain RNA - medulla oblongata [nTPM]":"59.3","Brain RNA - midbrain [nTPM]":"49.7","Brain RNA - pons [nTPM]":"55.9","Brain RNA - spinal cord [nTPM]":"35.8","Brain RNA - thalamus [nTPM]":"48.4","Brain RNA - white matter [nTPM]":"81.9","Single Cell Type RNA - Adipocytes [nTPM]":"43.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.6","Single Cell Type RNA - Astrocytes [nTPM]":"8.1","Single Cell Type RNA - B-cells [nTPM]":"69.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"3.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"41.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - dendritic cells [nTPM]":"79.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"41.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.6","Single Cell Type RNA - Endothelial cells [nTPM]":"19.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.1","Single Cell Type RNA - Erythroid cells [nTPM]":"28.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.4","Single Cell Type RNA - Fibroblasts [nTPM]":"4.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.0","Single Cell Type RNA - granulocytes [nTPM]":"40.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.6","Single Cell Type RNA - Hepatocytes [nTPM]":"2.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"67.0","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.0","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"66.2","Single Cell Type RNA - Langerhans cells [nTPM]":"29.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"9.6","Single Cell Type RNA - Macrophages [nTPM]":"44.7","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"62.0","Single Cell Type RNA - Muller glia cells [nTPM]":"7.5","Single Cell Type RNA - NK-cells [nTPM]":"85.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"50.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"40.5","Single Cell Type RNA - Paneth cells [nTPM]":"53.7","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"62.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"31.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.8","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"2.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.7","Single Cell Type RNA - T-cells [nTPM]":"83.7","Single Cell Type RNA - Theca cells [nTPM]":"2.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"30.3","Single Cell Type RNA - Urothelial cells [nTPM]":"37.4"},{"Gene":"TMC8","Gene synonym":["EVER2","EVIN2"],"Ensembl":"ENSG00000167895","Gene description":"Transmembrane channel like 8","Uniprot":["Q8IU68"],"Chromosome":"17","Position":"78130770-78142968","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Transport"],"Molecular function":["Ion channel"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"bone marrow":"91.8","intestine":"54.6","lymphoid tissue":"117.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"44.9","dendritic cells":"52.3","granulocytes":"41.2","Langerhans cells":"44.6","NK-cells":"85.5","T-cells":"68.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"46.3","HL-60":"63.0","HMC-1":"119.9","Karpas-707":"103.9","RPMI-8226":"66.6","U-266\/70":"49.3","U-937":"51.9"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047387","HPA054429"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA047387":null,"HPA054429":"AB_2682485"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.45e-6"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.19e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.47e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.96e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.8","Tissue RNA - adrenal gland [nTPM]":"3.0","Tissue RNA - amygdala [nTPM]":"3.6","Tissue RNA - appendix [nTPM]":"56.0","Tissue RNA - basal ganglia [nTPM]":"4.4","Tissue RNA - bone marrow [nTPM]":"91.8","Tissue RNA - breast [nTPM]":"3.7","Tissue RNA - cerebellum [nTPM]":"3.7","Tissue RNA - cerebral cortex [nTPM]":"5.1","Tissue RNA - cervix [nTPM]":"3.7","Tissue RNA - choroid plexus [nTPM]":"3.5","Tissue RNA - colon [nTPM]":"8.2","Tissue RNA - duodenum [nTPM]":"10.3","Tissue RNA - endometrium 1 [nTPM]":"2.5","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"4.8","Tissue RNA - fallopian tube [nTPM]":"4.0","Tissue RNA - gallbladder [nTPM]":"7.4","Tissue RNA - heart muscle [nTPM]":"2.7","Tissue RNA - hippocampal formation [nTPM]":"3.6","Tissue RNA - hypothalamus [nTPM]":"4.8","Tissue RNA - kidney [nTPM]":"5.2","Tissue RNA - liver [nTPM]":"7.1","Tissue RNA - lung [nTPM]":"18.4","Tissue RNA - lymph node [nTPM]":"100.5","Tissue RNA - medulla oblongata [nTPM]":"5.8","Tissue RNA - midbrain [nTPM]":"4.7","Tissue RNA - ovary [nTPM]":"1.3","Tissue RNA - pancreas [nTPM]":"2.0","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":"2.2","Tissue RNA - placenta [nTPM]":"3.9","Tissue RNA - pons [nTPM]":"5.6","Tissue RNA - prostate [nTPM]":"4.9","Tissue RNA - rectum [nTPM]":"4.5","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"5.8","Tissue RNA - seminal vesicle [nTPM]":"1.3","Tissue RNA - skeletal muscle [nTPM]":"1.8","Tissue RNA - skin 1 [nTPM]":"3.6","Tissue RNA - small intestine [nTPM]":"54.6","Tissue RNA - smooth muscle [nTPM]":"2.4","Tissue RNA - spinal cord [nTPM]":"5.0","Tissue RNA - spleen [nTPM]":"117.0","Tissue RNA - stomach 1 [nTPM]":"10.4","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"7.8","Tissue RNA - thymus [nTPM]":"60.1","Tissue RNA - thyroid gland [nTPM]":"6.4","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"46.7","Tissue RNA - urinary bladder [nTPM]":"6.4","Tissue RNA - vagina [nTPM]":"5.0","Tissue RNA - white matter [nTPM]":"7.2","Cell RNA - A-431 [nTPM]":"0.5","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"1.3","Cell RNA - Daudi [nTPM]":"46.3","Cell RNA - EFO-21 [nTPM]":"2.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"3.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"16.4","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.8","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"63.0","Cell RNA - HMC-1 [nTPM]":"119.9","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"22.1","Cell RNA - K-562 [nTPM]":"4.0","Cell RNA - Karpas-707 [nTPM]":"103.9","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.3","Cell RNA - MOLT-4 [nTPM]":"20.9","Cell RNA - NB-4 [nTPM]":"2.8","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"3.5","Cell RNA - PC-3 [nTPM]":"0.5","Cell RNA - REH [nTPM]":"1.4","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"66.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"2.2","Cell RNA - SK-MEL-30 [nTPM]":"0.6","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"6.9","Cell RNA - THP-1 [nTPM]":"12.7","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"49.3","Cell RNA - U-266\/84 [nTPM]":"2.0","Cell RNA - U-698 [nTPM]":"4.6","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"51.9","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"2.6","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"6.6","Blood RNA - gdT-cell [nTPM]":"13.4","Blood RNA - intermediate monocyte [nTPM]":"3.4","Blood RNA - MAIT T-cell [nTPM]":"9.7","Blood RNA - memory B-cell [nTPM]":"5.5","Blood RNA - memory CD4 T-cell [nTPM]":"10.8","Blood RNA - memory CD8 T-cell [nTPM]":"13.3","Blood RNA - myeloid DC [nTPM]":"2.3","Blood RNA - naive B-cell [nTPM]":"4.8","Blood RNA - naive CD4 T-cell [nTPM]":"9.4","Blood RNA - naive CD8 T-cell [nTPM]":"8.6","Blood RNA - neutrophil [nTPM]":"3.3","Blood RNA - NK-cell [nTPM]":"7.5","Blood RNA - non-classical monocyte [nTPM]":"7.9","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"6.5","Blood RNA - total PBMC [nTPM]":"5.5","Brain RNA - amygdala [nTPM]":"3.6","Brain RNA - basal ganglia [nTPM]":"4.4","Brain RNA - cerebellum [nTPM]":"3.7","Brain RNA - cerebral cortex [nTPM]":"5.1","Brain RNA - hippocampal formation [nTPM]":"3.6","Brain RNA - hypothalamus [nTPM]":"4.8","Brain RNA - medulla oblongata [nTPM]":"5.8","Brain RNA - midbrain [nTPM]":"4.7","Brain RNA - pons [nTPM]":"5.6","Brain RNA - spinal cord [nTPM]":"5.0","Brain RNA - thalamus [nTPM]":"7.8","Brain RNA - white matter [nTPM]":"7.2","Single Cell Type RNA - Adipocytes [nTPM]":"3.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.2","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"44.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"6.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"52.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.6","Single Cell Type RNA - Endothelial cells [nTPM]":"3.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"17.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.4","Single Cell Type RNA - Fibroblasts [nTPM]":"2.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.8","Single Cell Type RNA - granulocytes [nTPM]":"41.2","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.4","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"28.2","Single Cell Type RNA - Langerhans cells [nTPM]":"44.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"22.0","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"24.4","Single Cell Type RNA - monocytes [nTPM]":"30.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"85.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"3.6","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"20.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"68.6","Single Cell Type RNA - Theca cells [nTPM]":"2.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.0","Single Cell Type RNA - Urothelial cells [nTPM]":"10.7"},{"Gene":"TNFAIP3","Gene synonym":["A20","OTUD7C"],"Ensembl":"ENSG00000118503","Gene description":"TNF alpha induced protein 3","Uniprot":["P21580"],"Chromosome":"6","Position":"137867214-137883312","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Inflammatory response","Ubl conjugation pathway"],"Molecular function":["DNA-binding","Hydrolase","Multifunctional enzyme","Protease","Thiol protease","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"519.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"774.9","Endometrial ciliated cells":"605.2","Glandular and luminal cells":"1498.3","Macrophages":"596.6","Suprabasal keratinocytes":"745.7","T-cells":"624.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"GAMG":"106.5","Karpas-707":"161.3","REH":"151.5","U-266\/84":"131.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002116"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Centrosome","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA002116":"AB_1858162"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.05e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Tissue RNA - adipose tissue [nTPM]":"57.0","Tissue RNA - adrenal gland [nTPM]":"15.6","Tissue RNA - amygdala [nTPM]":"4.4","Tissue RNA - appendix [nTPM]":"114.6","Tissue RNA - basal ganglia [nTPM]":"3.8","Tissue RNA - bone marrow [nTPM]":"519.5","Tissue RNA - breast [nTPM]":"23.3","Tissue RNA - cerebellum [nTPM]":"2.9","Tissue RNA - cerebral cortex [nTPM]":"23.9","Tissue RNA - cervix [nTPM]":"27.5","Tissue RNA - choroid plexus [nTPM]":"12.0","Tissue RNA - colon [nTPM]":"22.6","Tissue RNA - duodenum [nTPM]":"21.4","Tissue RNA - endometrium 1 [nTPM]":"31.3","Tissue RNA - epididymis [nTPM]":"5.2","Tissue RNA - esophagus [nTPM]":"26.6","Tissue RNA - fallopian tube [nTPM]":"23.4","Tissue RNA - gallbladder [nTPM]":"47.8","Tissue RNA - heart muscle [nTPM]":"23.0","Tissue RNA - hippocampal formation [nTPM]":"3.2","Tissue RNA - hypothalamus [nTPM]":"2.8","Tissue RNA - kidney [nTPM]":"13.8","Tissue RNA - liver [nTPM]":"27.4","Tissue RNA - lung [nTPM]":"56.2","Tissue RNA - lymph node [nTPM]":"76.8","Tissue RNA - medulla oblongata [nTPM]":"6.1","Tissue RNA - midbrain [nTPM]":"3.9","Tissue RNA - ovary [nTPM]":"73.2","Tissue RNA - pancreas [nTPM]":"25.8","Tissue RNA - parathyroid gland [nTPM]":"25.8","Tissue RNA - pituitary gland [nTPM]":"7.5","Tissue RNA - placenta [nTPM]":"28.9","Tissue RNA - pons [nTPM]":"6.7","Tissue RNA - prostate [nTPM]":"17.3","Tissue RNA - rectum [nTPM]":"24.7","Tissue RNA - retina [nTPM]":"19.1","Tissue RNA - salivary gland [nTPM]":"16.1","Tissue RNA - seminal vesicle [nTPM]":"10.3","Tissue RNA - skeletal muscle [nTPM]":"8.6","Tissue RNA - skin 1 [nTPM]":"50.5","Tissue RNA - small intestine [nTPM]":"30.7","Tissue RNA - smooth muscle [nTPM]":"33.5","Tissue RNA - spinal cord [nTPM]":"6.6","Tissue RNA - spleen [nTPM]":"46.1","Tissue RNA - stomach 1 [nTPM]":"22.8","Tissue RNA - testis [nTPM]":"8.3","Tissue RNA - thalamus [nTPM]":"9.5","Tissue RNA - thymus [nTPM]":"71.1","Tissue RNA - thyroid gland [nTPM]":"11.7","Tissue RNA - tongue [nTPM]":"3.8","Tissue RNA - tonsil [nTPM]":"55.7","Tissue RNA - urinary bladder [nTPM]":"171.1","Tissue RNA - vagina [nTPM]":"14.6","Tissue RNA - white matter [nTPM]":"6.2","Cell RNA - A-431 [nTPM]":"32.6","Cell RNA - A549 [nTPM]":"4.8","Cell RNA - AF22 [nTPM]":"1.8","Cell RNA - AN3-CA [nTPM]":"2.8","Cell RNA - ASC diff [nTPM]":"10.1","Cell RNA - ASC TERT1 [nTPM]":"16.9","Cell RNA - BEWO [nTPM]":"7.8","Cell RNA - BJ [nTPM]":"18.8","Cell RNA - BJ hTERT+ [nTPM]":"67.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.7","Cell RNA - CACO-2 [nTPM]":"34.9","Cell RNA - CAPAN-2 [nTPM]":"8.8","Cell RNA - Daudi [nTPM]":"7.3","Cell RNA - EFO-21 [nTPM]":"43.1","Cell RNA - fHDF\/TERT166 [nTPM]":"20.0","Cell RNA - GAMG [nTPM]":"106.5","Cell RNA - HaCaT [nTPM]":"22.6","Cell RNA - HAP1 [nTPM]":"1.1","Cell RNA - HBEC3-KT [nTPM]":"50.4","Cell RNA - HBF TERT88 [nTPM]":"8.9","Cell RNA - HDLM-2 [nTPM]":"46.8","Cell RNA - HEK 293 [nTPM]":"2.2","Cell RNA - HEL [nTPM]":"7.5","Cell RNA - HeLa [nTPM]":"19.8","Cell RNA - Hep G2 [nTPM]":"21.1","Cell RNA - HHSteC [nTPM]":"11.2","Cell RNA - HL-60 [nTPM]":"10.3","Cell RNA - HMC-1 [nTPM]":"12.8","Cell RNA - HSkMC [nTPM]":"15.6","Cell RNA - hTCEpi [nTPM]":"7.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"56.4","Cell RNA - hTERT-HME1 [nTPM]":"53.6","Cell RNA - hTERT-RPE1 [nTPM]":"5.6","Cell RNA - HUVEC TERT2 [nTPM]":"2.9","Cell RNA - JURKAT [nTPM]":"21.2","Cell RNA - K-562 [nTPM]":"17.4","Cell RNA - Karpas-707 [nTPM]":"161.3","Cell RNA - LHCN-M2 [nTPM]":"8.4","Cell RNA - MCF7 [nTPM]":"1.8","Cell RNA - MOLT-4 [nTPM]":"56.2","Cell RNA - NB-4 [nTPM]":"41.4","Cell RNA - NTERA-2 [nTPM]":"1.5","Cell RNA - OE19 [nTPM]":"2.1","Cell RNA - PC-3 [nTPM]":"1.4","Cell RNA - REH [nTPM]":"151.5","Cell RNA - RH-30 [nTPM]":"39.4","Cell RNA - RPMI-8226 [nTPM]":"6.1","Cell RNA - RPTEC TERT1 [nTPM]":"14.8","Cell RNA - RT4 [nTPM]":"15.1","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"3.6","Cell RNA - SK-BR-3 [nTPM]":"5.3","Cell RNA - SK-MEL-30 [nTPM]":"16.9","Cell RNA - SuSa [nTPM]":"7.0","Cell RNA - T-47d [nTPM]":"3.4","Cell RNA - THP-1 [nTPM]":"11.7","Cell RNA - TIME [nTPM]":"14.8","Cell RNA - U-138 MG [nTPM]":"46.9","Cell RNA - U-2 OS [nTPM]":"6.8","Cell RNA - U-2197 [nTPM]":"46.0","Cell RNA - U-251 MG [nTPM]":"9.6","Cell RNA - U-266\/70 [nTPM]":"48.7","Cell RNA - U-266\/84 [nTPM]":"131.4","Cell RNA - U-698 [nTPM]":"14.0","Cell RNA - U-87 MG [nTPM]":"16.9","Cell RNA - U-937 [nTPM]":"13.1","Cell RNA - WM-115 [nTPM]":"6.1","Blood RNA - basophil [nTPM]":"7.3","Blood RNA - classical monocyte [nTPM]":"12.6","Blood RNA - eosinophil [nTPM]":"9.6","Blood RNA - gdT-cell [nTPM]":"19.6","Blood RNA - intermediate monocyte [nTPM]":"9.3","Blood RNA - MAIT T-cell [nTPM]":"27.9","Blood RNA - memory B-cell [nTPM]":"7.4","Blood RNA - memory CD4 T-cell [nTPM]":"19.4","Blood RNA - memory CD8 T-cell [nTPM]":"18.0","Blood RNA - myeloid DC [nTPM]":"14.3","Blood RNA - naive B-cell [nTPM]":"7.8","Blood RNA - naive CD4 T-cell [nTPM]":"13.1","Blood RNA - naive CD8 T-cell [nTPM]":"10.1","Blood RNA - neutrophil [nTPM]":"13.6","Blood RNA - NK-cell [nTPM]":"11.1","Blood RNA - non-classical monocyte [nTPM]":"5.1","Blood RNA - plasmacytoid DC [nTPM]":"26.2","Blood RNA - T-reg [nTPM]":"19.2","Blood RNA - total PBMC [nTPM]":"14.8","Brain RNA - amygdala [nTPM]":"4.4","Brain RNA - basal ganglia [nTPM]":"3.8","Brain RNA - cerebellum [nTPM]":"2.9","Brain RNA - cerebral cortex [nTPM]":"23.9","Brain RNA - hippocampal formation [nTPM]":"3.2","Brain RNA - hypothalamus [nTPM]":"2.8","Brain RNA - medulla oblongata [nTPM]":"6.1","Brain RNA - midbrain [nTPM]":"3.9","Brain RNA - pons [nTPM]":"6.7","Brain RNA - spinal cord [nTPM]":"6.6","Brain RNA - thalamus [nTPM]":"9.5","Brain RNA - white matter [nTPM]":"6.2","Single Cell Type RNA - Adipocytes [nTPM]":"71.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"76.3","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"94.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"774.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"150.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"102.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"384.7","Single Cell Type RNA - Bipolar cells [nTPM]":"1.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"42.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"53.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.1","Single Cell Type RNA - dendritic cells [nTPM]":"395.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"53.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"60.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"605.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"365.9","Single Cell Type RNA - Endothelial cells [nTPM]":"114.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.9","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"104.8","Single Cell Type RNA - Fibroblasts [nTPM]":"110.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"111.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1498.3","Single Cell Type RNA - granulocytes [nTPM]":"255.9","Single Cell Type RNA - Granulosa cells [nTPM]":"2.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"48.5","Single Cell Type RNA - Hepatocytes [nTPM]":"13.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"45.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"38.6","Single Cell Type RNA - Ionocytes [nTPM]":"67.1","Single Cell Type RNA - Kupffer cells [nTPM]":"125.2","Single Cell Type RNA - Langerhans cells [nTPM]":"461.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"6.8","Single Cell Type RNA - Macrophages [nTPM]":"596.6","Single Cell Type RNA - Melanocytes [nTPM]":"129.9","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"59.1","Single Cell Type RNA - Muller glia cells [nTPM]":"1.7","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"30.5","Single Cell Type RNA - Paneth cells [nTPM]":"29.5","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"331.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"170.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"37.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"84.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"29.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"94.9","Single Cell Type RNA - Spermatocytes [nTPM]":"2.7","Single Cell Type RNA - Spermatogonia [nTPM]":"2.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"367.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"745.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.1","Single Cell Type RNA - T-cells [nTPM]":"624.2","Single Cell Type RNA - Theca cells [nTPM]":"14.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.9","Single Cell Type RNA - Urothelial cells [nTPM]":"78.1"},{"Gene":"TNFSF4","Gene synonym":["CD252","gp34","OX-40L","TXGP1"],"Ensembl":"ENSG00000117586","Gene description":"TNF superfamily member 4","Uniprot":["P23510"],"Chromosome":"1","Position":"173183731-173207331","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Cytokine"],"Disease involvement":["Cancer-related genes","Systemic lupus erythematosus"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"8.5","Granulosa cells":"37.0","Macrophages":"26.4","monocytes":"8.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"fHDF\/TERT166":"42.0","HHSteC":"17.3","HUVEC TERT2":"81.2","LHCN-M2":"67.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059579"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 32: Brain & Lymphoid tissue - Unknown function","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 51: Myeloid cells - Hemostasis","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA059579":"AB_2684071"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.2","Tissue RNA - adrenal gland [nTPM]":"2.0","Tissue RNA - amygdala [nTPM]":"1.1","Tissue RNA - appendix [nTPM]":"2.3","Tissue RNA - basal ganglia [nTPM]":"1.2","Tissue RNA - bone marrow [nTPM]":"0.6","Tissue RNA - breast [nTPM]":"0.6","Tissue RNA - cerebellum [nTPM]":"1.8","Tissue RNA - cerebral cortex [nTPM]":"1.5","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"1.0","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.8","Tissue RNA - epididymis [nTPM]":"0.5","Tissue RNA - esophagus [nTPM]":"0.6","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"1.0","Tissue RNA - hippocampal formation [nTPM]":"1.1","Tissue RNA - hypothalamus [nTPM]":"0.9","Tissue RNA - kidney [nTPM]":"0.8","Tissue RNA - liver [nTPM]":"0.9","Tissue RNA - lung [nTPM]":"1.2","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"1.2","Tissue RNA - midbrain [nTPM]":"1.2","Tissue RNA - ovary [nTPM]":"1.1","Tissue RNA - pancreas [nTPM]":"1.1","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"1.2","Tissue RNA - prostate [nTPM]":"1.4","Tissue RNA - rectum [nTPM]":"1.2","Tissue RNA - retina [nTPM]":"1.4","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.8","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"1.7","Tissue RNA - stomach 1 [nTPM]":"0.7","Tissue RNA - testis [nTPM]":"4.0","Tissue RNA - thalamus [nTPM]":"1.1","Tissue RNA - thymus [nTPM]":"3.7","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"1.9","Tissue RNA - urinary bladder [nTPM]":"1.5","Tissue RNA - vagina [nTPM]":"0.8","Tissue RNA - white matter [nTPM]":"1.2","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"1.2","Cell RNA - ASC diff [nTPM]":"2.7","Cell RNA - ASC TERT1 [nTPM]":"14.1","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"4.1","Cell RNA - BJ hTERT+ [nTPM]":"0.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.7","Cell RNA - fHDF\/TERT166 [nTPM]":"42.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"0.7","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"1.6","Cell RNA - HHSteC [nTPM]":"17.3","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"6.2","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.1","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"1.3","Cell RNA - HUVEC TERT2 [nTPM]":"81.2","Cell RNA - JURKAT [nTPM]":"1.5","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"67.5","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.7","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.6","Cell RNA - REH [nTPM]":"2.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.6","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.9","Cell RNA - SuSa [nTPM]":"1.3","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.7","Cell RNA - TIME [nTPM]":"0.6","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.4","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"1.4","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"7.7","Cell RNA - WM-115 [nTPM]":"4.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"1.7","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"2.8","Brain RNA - amygdala [nTPM]":"1.1","Brain RNA - basal ganglia [nTPM]":"1.2","Brain RNA - cerebellum [nTPM]":"1.8","Brain RNA - cerebral cortex [nTPM]":"1.5","Brain RNA - hippocampal formation [nTPM]":"1.1","Brain RNA - hypothalamus [nTPM]":"0.9","Brain RNA - medulla oblongata [nTPM]":"1.2","Brain RNA - midbrain [nTPM]":"1.2","Brain RNA - pons [nTPM]":"1.2","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"1.1","Brain RNA - white matter [nTPM]":"1.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"8.5","Single Cell Type RNA - B-cells [nTPM]":"0.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"2.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"5.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"3.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"37.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"2.3","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"26.4","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"8.2","Single Cell Type RNA - Muller glia cells [nTPM]":"1.3","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"2.4","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"TNIP1","Gene synonym":["ABIN-1","KIAA0113","NAF1","VAN"],"Ensembl":"ENSG00000145901","Gene description":"TNFAIP3 interacting protein 1","Uniprot":["Q15025"],"Chromosome":"5","Position":"151029945-151093577","Protein class":["Human disease related genes","Predicted intracellular proteins"],"Biological process":["Inflammatory response"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Pancreatic endocrine cells":"265.5","Proximal enterocytes":"257.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HBEC3-KT":"406.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA037893","HPA037894","HPA071950"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA037893":"AB_10672468","HPA037894":"AB_2675723","HPA071950":"AB_2686476"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.69e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.86e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.45e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.35e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.42e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.68e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.84e-2"},"Tissue RNA - adipose tissue [nTPM]":"120.0","Tissue RNA - adrenal gland [nTPM]":"49.7","Tissue RNA - amygdala [nTPM]":"34.1","Tissue RNA - appendix [nTPM]":"79.6","Tissue RNA - basal ganglia [nTPM]":"33.4","Tissue RNA - bone marrow [nTPM]":"128.0","Tissue RNA - breast [nTPM]":"90.7","Tissue RNA - cerebellum [nTPM]":"35.3","Tissue RNA - cerebral cortex [nTPM]":"40.8","Tissue RNA - cervix [nTPM]":"60.1","Tissue RNA - choroid plexus [nTPM]":"33.3","Tissue RNA - colon [nTPM]":"72.7","Tissue RNA - duodenum [nTPM]":"73.2","Tissue RNA - endometrium 1 [nTPM]":"37.6","Tissue RNA - epididymis [nTPM]":"22.4","Tissue RNA - esophagus [nTPM]":"89.3","Tissue RNA - fallopian tube [nTPM]":"37.9","Tissue RNA - gallbladder [nTPM]":"54.3","Tissue RNA - heart muscle [nTPM]":"96.3","Tissue RNA - hippocampal formation [nTPM]":"31.5","Tissue RNA - hypothalamus [nTPM]":"36.5","Tissue RNA - kidney [nTPM]":"83.3","Tissue RNA - liver [nTPM]":"107.9","Tissue RNA - lung [nTPM]":"91.7","Tissue RNA - lymph node [nTPM]":"69.4","Tissue RNA - medulla oblongata [nTPM]":"40.5","Tissue RNA - midbrain [nTPM]":"37.4","Tissue RNA - ovary [nTPM]":"41.8","Tissue RNA - pancreas [nTPM]":"71.6","Tissue RNA - parathyroid gland [nTPM]":"42.8","Tissue RNA - pituitary gland [nTPM]":"27.2","Tissue RNA - placenta [nTPM]":"28.7","Tissue RNA - pons [nTPM]":"39.0","Tissue RNA - prostate [nTPM]":"47.9","Tissue RNA - rectum [nTPM]":"52.4","Tissue RNA - retina [nTPM]":"17.4","Tissue RNA - salivary gland [nTPM]":"53.1","Tissue RNA - seminal vesicle [nTPM]":"39.2","Tissue RNA - skeletal muscle [nTPM]":"211.2","Tissue RNA - skin 1 [nTPM]":"60.4","Tissue RNA - small intestine [nTPM]":"90.8","Tissue RNA - smooth muscle [nTPM]":"32.6","Tissue RNA - spinal cord [nTPM]":"37.6","Tissue RNA - spleen [nTPM]":"101.2","Tissue RNA - stomach 1 [nTPM]":"63.5","Tissue RNA - testis [nTPM]":"14.6","Tissue RNA - thalamus [nTPM]":"37.1","Tissue RNA - thymus [nTPM]":"43.4","Tissue RNA - thyroid gland [nTPM]":"45.9","Tissue RNA - tongue [nTPM]":"130.7","Tissue RNA - tonsil [nTPM]":"83.3","Tissue RNA - urinary bladder [nTPM]":"84.4","Tissue RNA - vagina [nTPM]":"69.3","Tissue RNA - white matter [nTPM]":"35.3","Cell RNA - A-431 [nTPM]":"117.7","Cell RNA - A549 [nTPM]":"81.3","Cell RNA - AF22 [nTPM]":"15.4","Cell RNA - AN3-CA [nTPM]":"55.7","Cell RNA - ASC diff [nTPM]":"58.4","Cell RNA - ASC TERT1 [nTPM]":"58.6","Cell RNA - BEWO [nTPM]":"39.4","Cell RNA - BJ [nTPM]":"54.7","Cell RNA - BJ hTERT+ [nTPM]":"174.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"48.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"91.1","Cell RNA - CACO-2 [nTPM]":"78.4","Cell RNA - CAPAN-2 [nTPM]":"155.5","Cell RNA - Daudi [nTPM]":"95.8","Cell RNA - EFO-21 [nTPM]":"182.3","Cell RNA - fHDF\/TERT166 [nTPM]":"74.2","Cell RNA - GAMG [nTPM]":"285.3","Cell RNA - HaCaT [nTPM]":"68.3","Cell RNA - HAP1 [nTPM]":"25.2","Cell RNA - HBEC3-KT [nTPM]":"406.4","Cell RNA - HBF TERT88 [nTPM]":"59.4","Cell RNA - HDLM-2 [nTPM]":"167.8","Cell RNA - HEK 293 [nTPM]":"34.6","Cell RNA - HEL [nTPM]":"37.8","Cell RNA - HeLa [nTPM]":"44.4","Cell RNA - Hep G2 [nTPM]":"51.1","Cell RNA - HHSteC [nTPM]":"111.4","Cell RNA - HL-60 [nTPM]":"43.6","Cell RNA - HMC-1 [nTPM]":"168.3","Cell RNA - HSkMC [nTPM]":"84.3","Cell RNA - hTCEpi [nTPM]":"74.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"80.3","Cell RNA - hTERT-HME1 [nTPM]":"166.2","Cell RNA - hTERT-RPE1 [nTPM]":"134.1","Cell RNA - HUVEC TERT2 [nTPM]":"69.1","Cell RNA - JURKAT [nTPM]":"37.2","Cell RNA - K-562 [nTPM]":"24.6","Cell RNA - Karpas-707 [nTPM]":"94.2","Cell RNA - LHCN-M2 [nTPM]":"122.7","Cell RNA - MCF7 [nTPM]":"43.7","Cell RNA - MOLT-4 [nTPM]":"48.2","Cell RNA - NB-4 [nTPM]":"60.0","Cell RNA - NTERA-2 [nTPM]":"13.9","Cell RNA - OE19 [nTPM]":"41.1","Cell RNA - PC-3 [nTPM]":"43.4","Cell RNA - REH [nTPM]":"39.0","Cell RNA - RH-30 [nTPM]":"118.4","Cell RNA - RPMI-8226 [nTPM]":"131.4","Cell RNA - RPTEC TERT1 [nTPM]":"152.3","Cell RNA - RT4 [nTPM]":"85.0","Cell RNA - SCLC-21H [nTPM]":"21.7","Cell RNA - SH-SY5Y [nTPM]":"49.9","Cell RNA - SiHa [nTPM]":"42.4","Cell RNA - SK-BR-3 [nTPM]":"131.5","Cell RNA - SK-MEL-30 [nTPM]":"57.2","Cell RNA - SuSa [nTPM]":"41.6","Cell RNA - T-47d [nTPM]":"67.5","Cell RNA - THP-1 [nTPM]":"54.5","Cell RNA - TIME [nTPM]":"107.8","Cell RNA - U-138 MG [nTPM]":"162.7","Cell RNA - U-2 OS [nTPM]":"53.0","Cell RNA - U-2197 [nTPM]":"28.7","Cell RNA - U-251 MG [nTPM]":"79.2","Cell RNA - U-266\/70 [nTPM]":"184.6","Cell RNA - U-266\/84 [nTPM]":"102.2","Cell RNA - U-698 [nTPM]":"43.4","Cell RNA - U-87 MG [nTPM]":"177.0","Cell RNA - U-937 [nTPM]":"63.7","Cell RNA - WM-115 [nTPM]":"39.6","Blood RNA - basophil [nTPM]":"18.2","Blood RNA - classical monocyte [nTPM]":"12.1","Blood RNA - eosinophil [nTPM]":"36.0","Blood RNA - gdT-cell [nTPM]":"11.9","Blood RNA - intermediate monocyte [nTPM]":"11.1","Blood RNA - MAIT T-cell [nTPM]":"14.0","Blood RNA - memory B-cell [nTPM]":"12.7","Blood RNA - memory CD4 T-cell [nTPM]":"13.9","Blood RNA - memory CD8 T-cell [nTPM]":"12.0","Blood RNA - myeloid DC [nTPM]":"9.2","Blood RNA - naive B-cell [nTPM]":"16.8","Blood RNA - naive CD4 T-cell [nTPM]":"7.1","Blood RNA - naive CD8 T-cell [nTPM]":"7.9","Blood RNA - neutrophil [nTPM]":"41.3","Blood RNA - NK-cell [nTPM]":"12.4","Blood RNA - non-classical monocyte [nTPM]":"10.8","Blood RNA - plasmacytoid DC [nTPM]":"12.8","Blood RNA - T-reg [nTPM]":"21.2","Blood RNA - total PBMC [nTPM]":"10.4","Brain RNA - amygdala [nTPM]":"34.1","Brain RNA - basal ganglia [nTPM]":"33.4","Brain RNA - cerebellum [nTPM]":"35.3","Brain RNA - cerebral cortex [nTPM]":"40.8","Brain RNA - hippocampal formation [nTPM]":"31.5","Brain RNA - hypothalamus [nTPM]":"36.5","Brain RNA - medulla oblongata [nTPM]":"40.5","Brain RNA - midbrain [nTPM]":"37.4","Brain RNA - pons [nTPM]":"39.0","Brain RNA - spinal cord [nTPM]":"37.6","Brain RNA - thalamus [nTPM]":"37.1","Brain RNA - white matter [nTPM]":"35.3","Single Cell Type RNA - Adipocytes [nTPM]":"31.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"57.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"45.4","Single Cell Type RNA - Astrocytes [nTPM]":"4.9","Single Cell Type RNA - B-cells [nTPM]":"73.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"29.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"50.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"119.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.3","Single Cell Type RNA - Bipolar cells [nTPM]":"14.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"48.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"54.3","Single Cell Type RNA - Club cells [nTPM]":"72.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.3","Single Cell Type RNA - dendritic cells [nTPM]":"53.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"233.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"72.4","Single Cell Type RNA - Ductal cells [nTPM]":"218.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"39.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.0","Single Cell Type RNA - Endothelial cells [nTPM]":"75.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"37.3","Single Cell Type RNA - Erythroid cells [nTPM]":"52.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"139.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"31.3","Single Cell Type RNA - Fibroblasts [nTPM]":"38.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"92.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"64.8","Single Cell Type RNA - granulocytes [nTPM]":"48.2","Single Cell Type RNA - Granulosa cells [nTPM]":"105.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"42.1","Single Cell Type RNA - Hepatocytes [nTPM]":"62.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"39.0","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"69.0","Single Cell Type RNA - Ionocytes [nTPM]":"46.8","Single Cell Type RNA - Kupffer cells [nTPM]":"49.6","Single Cell Type RNA - Langerhans cells [nTPM]":"113.1","Single Cell Type RNA - Late spermatids [nTPM]":"6.9","Single Cell Type RNA - Leydig cells [nTPM]":"27.1","Single Cell Type RNA - Macrophages [nTPM]":"64.9","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"238.3","Single Cell Type RNA - Muller glia cells [nTPM]":"20.3","Single Cell Type RNA - NK-cells [nTPM]":"68.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"265.5","Single Cell Type RNA - Paneth cells [nTPM]":"173.9","Single Cell Type RNA - Peritubular cells [nTPM]":"23.7","Single Cell Type RNA - Plasma cells [nTPM]":"63.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"179.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"257.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"56.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"49.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.0","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"69.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"45.7","Single Cell Type RNA - Spermatocytes [nTPM]":"2.2","Single Cell Type RNA - Spermatogonia [nTPM]":"13.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"30.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"28.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"48.2","Single Cell Type RNA - T-cells [nTPM]":"60.7","Single Cell Type RNA - Theca cells [nTPM]":"12.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"77.1","Single Cell Type RNA - Urothelial cells [nTPM]":"158.6"},{"Gene":"TRAF3IP2","Gene synonym":["ACT1","C6orf2","C6orf4","C6orf5","C6orf6","CIKS","DKFZP586G0522"],"Ensembl":"ENSG00000056972","Gene description":"TRAF3 interacting protein 2","Uniprot":["O43734"],"Chromosome":"6","Position":"111555381-111606906","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Inflammatory response","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"61.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-2197":"149.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036352"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 68: Epididymis - Unknown function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA036352":"AB_10672085"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.21e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.73e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.93e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.16e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Tissue RNA - adipose tissue [nTPM]":"19.7","Tissue RNA - adrenal gland [nTPM]":"16.3","Tissue RNA - amygdala [nTPM]":"24.8","Tissue RNA - appendix [nTPM]":"19.5","Tissue RNA - basal ganglia [nTPM]":"24.8","Tissue RNA - bone marrow [nTPM]":"32.4","Tissue RNA - breast [nTPM]":"19.9","Tissue RNA - cerebellum [nTPM]":"24.3","Tissue RNA - cerebral cortex [nTPM]":"29.4","Tissue RNA - cervix [nTPM]":"24.9","Tissue RNA - choroid plexus [nTPM]":"23.7","Tissue RNA - colon [nTPM]":"34.0","Tissue RNA - duodenum [nTPM]":"28.6","Tissue RNA - endometrium 1 [nTPM]":"36.2","Tissue RNA - epididymis [nTPM]":"47.2","Tissue RNA - esophagus [nTPM]":"26.5","Tissue RNA - fallopian tube [nTPM]":"34.7","Tissue RNA - gallbladder [nTPM]":"14.2","Tissue RNA - heart muscle [nTPM]":"8.3","Tissue RNA - hippocampal formation [nTPM]":"24.4","Tissue RNA - hypothalamus [nTPM]":"26.0","Tissue RNA - kidney [nTPM]":"9.3","Tissue RNA - liver [nTPM]":"8.6","Tissue RNA - lung [nTPM]":"17.5","Tissue RNA - lymph node [nTPM]":"16.3","Tissue RNA - medulla oblongata [nTPM]":"27.2","Tissue RNA - midbrain [nTPM]":"28.2","Tissue RNA - ovary [nTPM]":"13.9","Tissue RNA - pancreas [nTPM]":"21.6","Tissue RNA - parathyroid gland [nTPM]":"13.6","Tissue RNA - pituitary gland [nTPM]":"9.3","Tissue RNA - placenta [nTPM]":"14.2","Tissue RNA - pons [nTPM]":"25.6","Tissue RNA - prostate [nTPM]":"19.2","Tissue RNA - rectum [nTPM]":"26.4","Tissue RNA - retina [nTPM]":"5.9","Tissue RNA - salivary gland [nTPM]":"25.3","Tissue RNA - seminal vesicle [nTPM]":"30.8","Tissue RNA - skeletal muscle [nTPM]":"11.4","Tissue RNA - skin 1 [nTPM]":"35.0","Tissue RNA - small intestine [nTPM]":"25.1","Tissue RNA - smooth muscle [nTPM]":"22.1","Tissue RNA - spinal cord [nTPM]":"21.7","Tissue RNA - spleen [nTPM]":"6.8","Tissue RNA - stomach 1 [nTPM]":"35.5","Tissue RNA - testis [nTPM]":"3.0","Tissue RNA - thalamus [nTPM]":"28.7","Tissue RNA - thymus [nTPM]":"21.0","Tissue RNA - thyroid gland [nTPM]":"14.8","Tissue RNA - tongue [nTPM]":"14.8","Tissue RNA - tonsil [nTPM]":"22.5","Tissue RNA - urinary bladder [nTPM]":"26.5","Tissue RNA - vagina [nTPM]":"18.1","Tissue RNA - white matter [nTPM]":"22.9","Cell RNA - A-431 [nTPM]":"32.2","Cell RNA - A549 [nTPM]":"11.0","Cell RNA - AF22 [nTPM]":"6.8","Cell RNA - AN3-CA [nTPM]":"15.7","Cell RNA - ASC diff [nTPM]":"35.9","Cell RNA - ASC TERT1 [nTPM]":"39.0","Cell RNA - BEWO [nTPM]":"15.6","Cell RNA - BJ [nTPM]":"39.8","Cell RNA - BJ hTERT+ [nTPM]":"62.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"14.1","Cell RNA - CACO-2 [nTPM]":"8.7","Cell RNA - CAPAN-2 [nTPM]":"14.1","Cell RNA - Daudi [nTPM]":"6.2","Cell RNA - EFO-21 [nTPM]":"13.2","Cell RNA - fHDF\/TERT166 [nTPM]":"33.5","Cell RNA - GAMG [nTPM]":"35.5","Cell RNA - HaCaT [nTPM]":"58.2","Cell RNA - HAP1 [nTPM]":"8.0","Cell RNA - HBEC3-KT [nTPM]":"86.2","Cell RNA - HBF TERT88 [nTPM]":"18.4","Cell RNA - HDLM-2 [nTPM]":"43.2","Cell RNA - HEK 293 [nTPM]":"11.6","Cell RNA - HEL [nTPM]":"12.7","Cell RNA - HeLa [nTPM]":"10.6","Cell RNA - Hep G2 [nTPM]":"11.9","Cell RNA - HHSteC [nTPM]":"13.9","Cell RNA - HL-60 [nTPM]":"6.9","Cell RNA - HMC-1 [nTPM]":"22.6","Cell RNA - HSkMC [nTPM]":"47.1","Cell RNA - hTCEpi [nTPM]":"57.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"29.9","Cell RNA - hTERT-HME1 [nTPM]":"110.1","Cell RNA - hTERT-RPE1 [nTPM]":"24.9","Cell RNA - HUVEC TERT2 [nTPM]":"20.0","Cell RNA - JURKAT [nTPM]":"15.2","Cell RNA - K-562 [nTPM]":"13.6","Cell RNA - Karpas-707 [nTPM]":"1.9","Cell RNA - LHCN-M2 [nTPM]":"13.2","Cell RNA - MCF7 [nTPM]":"22.0","Cell RNA - MOLT-4 [nTPM]":"51.2","Cell RNA - NB-4 [nTPM]":"19.4","Cell RNA - NTERA-2 [nTPM]":"9.0","Cell RNA - OE19 [nTPM]":"30.6","Cell RNA - PC-3 [nTPM]":"8.8","Cell RNA - REH [nTPM]":"53.3","Cell RNA - RH-30 [nTPM]":"12.4","Cell RNA - RPMI-8226 [nTPM]":"2.7","Cell RNA - RPTEC TERT1 [nTPM]":"29.5","Cell RNA - RT4 [nTPM]":"52.4","Cell RNA - SCLC-21H [nTPM]":"27.3","Cell RNA - SH-SY5Y [nTPM]":"6.9","Cell RNA - SiHa [nTPM]":"12.1","Cell RNA - SK-BR-3 [nTPM]":"71.8","Cell RNA - SK-MEL-30 [nTPM]":"47.8","Cell RNA - SuSa [nTPM]":"12.7","Cell RNA - T-47d [nTPM]":"31.6","Cell RNA - THP-1 [nTPM]":"18.0","Cell RNA - TIME [nTPM]":"9.2","Cell RNA - U-138 MG [nTPM]":"19.2","Cell RNA - U-2 OS [nTPM]":"7.6","Cell RNA - U-2197 [nTPM]":"149.7","Cell RNA - U-251 MG [nTPM]":"35.5","Cell RNA - U-266\/70 [nTPM]":"0.8","Cell RNA - U-266\/84 [nTPM]":"12.4","Cell RNA - U-698 [nTPM]":"16.8","Cell RNA - U-87 MG [nTPM]":"45.8","Cell RNA - U-937 [nTPM]":"10.8","Cell RNA - WM-115 [nTPM]":"50.1","Blood RNA - basophil [nTPM]":"25.8","Blood RNA - classical monocyte [nTPM]":"2.5","Blood RNA - eosinophil [nTPM]":"5.3","Blood RNA - gdT-cell [nTPM]":"3.8","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"12.7","Blood RNA - memory B-cell [nTPM]":"6.4","Blood RNA - memory CD4 T-cell [nTPM]":"7.6","Blood RNA - memory CD8 T-cell [nTPM]":"5.6","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"8.6","Blood RNA - naive CD4 T-cell [nTPM]":"7.6","Blood RNA - naive CD8 T-cell [nTPM]":"7.4","Blood RNA - neutrophil [nTPM]":"3.5","Blood RNA - NK-cell [nTPM]":"5.7","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"17.9","Blood RNA - total PBMC [nTPM]":"3.1","Brain RNA - amygdala [nTPM]":"24.8","Brain RNA - basal ganglia [nTPM]":"24.8","Brain RNA - cerebellum [nTPM]":"24.3","Brain RNA - cerebral cortex [nTPM]":"29.4","Brain RNA - hippocampal formation [nTPM]":"24.4","Brain RNA - hypothalamus [nTPM]":"26.0","Brain RNA - medulla oblongata [nTPM]":"27.2","Brain RNA - midbrain [nTPM]":"28.2","Brain RNA - pons [nTPM]":"25.6","Brain RNA - spinal cord [nTPM]":"21.7","Brain RNA - thalamus [nTPM]":"28.7","Brain RNA - white matter [nTPM]":"22.9","Single Cell Type RNA - Adipocytes [nTPM]":"24.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.8","Single Cell Type RNA - Astrocytes [nTPM]":"26.1","Single Cell Type RNA - B-cells [nTPM]":"10.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"61.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"46.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"7.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"21.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.3","Single Cell Type RNA - dendritic cells [nTPM]":"3.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"30.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"35.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.5","Single Cell Type RNA - Endothelial cells [nTPM]":"18.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.2","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"31.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.8","Single Cell Type RNA - Fibroblasts [nTPM]":"14.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"32.7","Single Cell Type RNA - granulocytes [nTPM]":"20.2","Single Cell Type RNA - Granulosa cells [nTPM]":"7.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"5.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.0","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.9","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"10.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"5.8","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"6.2","Single Cell Type RNA - Muller glia cells [nTPM]":"14.2","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.2","Single Cell Type RNA - Paneth cells [nTPM]":"26.3","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"4.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"42.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"2.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.9","Single Cell Type RNA - T-cells [nTPM]":"7.9","Single Cell Type RNA - Theca cells [nTPM]":"4.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"21.9","Single Cell Type RNA - Urothelial cells [nTPM]":"45.0"},{"Gene":"USB1","Gene synonym":["C16orf57","FLJ13154","HVSL1","Mpn1"],"Ensembl":"ENSG00000103005","Gene description":"U6 snRNA biogenesis phosphodiesterase 1","Uniprot":["Q9BQ65"],"Chromosome":"16","Position":"57999546-58021618","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Nuclease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041791","HPA059854"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA041791":"AB_10793933","HPA059854":"AB_2684143"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.69e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.02e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-2"},"Tissue RNA - adipose tissue [nTPM]":"21.5","Tissue RNA - adrenal gland [nTPM]":"27.5","Tissue RNA - amygdala [nTPM]":"24.0","Tissue RNA - appendix [nTPM]":"27.6","Tissue RNA - basal ganglia [nTPM]":"23.4","Tissue RNA - bone marrow [nTPM]":"30.9","Tissue RNA - breast [nTPM]":"14.8","Tissue RNA - cerebellum [nTPM]":"22.4","Tissue RNA - cerebral cortex [nTPM]":"26.2","Tissue RNA - cervix [nTPM]":"15.6","Tissue RNA - choroid plexus [nTPM]":"20.9","Tissue RNA - colon [nTPM]":"22.8","Tissue RNA - duodenum [nTPM]":"14.3","Tissue RNA - endometrium 1 [nTPM]":"19.0","Tissue RNA - epididymis [nTPM]":"16.3","Tissue RNA - esophagus [nTPM]":"17.4","Tissue RNA - fallopian tube [nTPM]":"15.7","Tissue RNA - gallbladder [nTPM]":"14.7","Tissue RNA - heart muscle [nTPM]":"27.7","Tissue RNA - hippocampal formation [nTPM]":"23.6","Tissue RNA - hypothalamus [nTPM]":"25.8","Tissue RNA - kidney [nTPM]":"19.0","Tissue RNA - liver [nTPM]":"29.9","Tissue RNA - lung [nTPM]":"20.5","Tissue RNA - lymph node [nTPM]":"20.2","Tissue RNA - medulla oblongata [nTPM]":"26.5","Tissue RNA - midbrain [nTPM]":"24.9","Tissue RNA - ovary [nTPM]":"11.8","Tissue RNA - pancreas [nTPM]":"17.6","Tissue RNA - parathyroid gland [nTPM]":"14.7","Tissue RNA - pituitary gland [nTPM]":"13.4","Tissue RNA - placenta [nTPM]":"16.6","Tissue RNA - pons [nTPM]":"26.3","Tissue RNA - prostate [nTPM]":"17.2","Tissue RNA - rectum [nTPM]":"18.6","Tissue RNA - retina [nTPM]":"6.7","Tissue RNA - salivary gland [nTPM]":"14.1","Tissue RNA - seminal vesicle [nTPM]":"18.4","Tissue RNA - skeletal muscle [nTPM]":"15.6","Tissue RNA - skin 1 [nTPM]":"15.2","Tissue RNA - small intestine [nTPM]":"18.1","Tissue RNA - smooth muscle [nTPM]":"24.8","Tissue RNA - spinal cord [nTPM]":"23.8","Tissue RNA - spleen [nTPM]":"25.7","Tissue RNA - stomach 1 [nTPM]":"19.4","Tissue RNA - testis [nTPM]":"20.2","Tissue RNA - thalamus [nTPM]":"25.7","Tissue RNA - thymus [nTPM]":"18.4","Tissue RNA - thyroid gland [nTPM]":"19.1","Tissue RNA - tongue [nTPM]":"13.0","Tissue RNA - tonsil [nTPM]":"20.8","Tissue RNA - urinary bladder [nTPM]":"28.1","Tissue RNA - vagina [nTPM]":"15.4","Tissue RNA - white matter [nTPM]":"23.5","Cell RNA - A-431 [nTPM]":"53.2","Cell RNA - A549 [nTPM]":"109.2","Cell RNA - AF22 [nTPM]":"36.5","Cell RNA - AN3-CA [nTPM]":"69.7","Cell RNA - ASC diff [nTPM]":"46.4","Cell RNA - ASC TERT1 [nTPM]":"32.5","Cell RNA - BEWO [nTPM]":"57.6","Cell RNA - BJ [nTPM]":"43.9","Cell RNA - BJ hTERT+ [nTPM]":"58.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"68.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"48.3","Cell RNA - CACO-2 [nTPM]":"70.9","Cell RNA - CAPAN-2 [nTPM]":"31.0","Cell RNA - Daudi [nTPM]":"32.5","Cell RNA - EFO-21 [nTPM]":"56.6","Cell RNA - fHDF\/TERT166 [nTPM]":"65.3","Cell RNA - GAMG [nTPM]":"61.0","Cell RNA - HaCaT [nTPM]":"38.6","Cell RNA - HAP1 [nTPM]":"58.2","Cell RNA - HBEC3-KT [nTPM]":"93.6","Cell RNA - HBF TERT88 [nTPM]":"97.6","Cell RNA - HDLM-2 [nTPM]":"31.9","Cell RNA - HEK 293 [nTPM]":"32.9","Cell RNA - HEL [nTPM]":"40.5","Cell RNA - HeLa [nTPM]":"43.0","Cell RNA - Hep G2 [nTPM]":"103.8","Cell RNA - HHSteC [nTPM]":"52.7","Cell RNA - HL-60 [nTPM]":"54.2","Cell RNA - HMC-1 [nTPM]":"114.1","Cell RNA - HSkMC [nTPM]":"46.6","Cell RNA - hTCEpi [nTPM]":"54.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"87.2","Cell RNA - hTERT-HME1 [nTPM]":"50.8","Cell RNA - hTERT-RPE1 [nTPM]":"45.4","Cell RNA - HUVEC TERT2 [nTPM]":"76.1","Cell RNA - JURKAT [nTPM]":"69.7","Cell RNA - K-562 [nTPM]":"55.4","Cell RNA - Karpas-707 [nTPM]":"15.4","Cell RNA - LHCN-M2 [nTPM]":"58.2","Cell RNA - MCF7 [nTPM]":"56.0","Cell RNA - MOLT-4 [nTPM]":"50.1","Cell RNA - NB-4 [nTPM]":"62.3","Cell RNA - NTERA-2 [nTPM]":"60.6","Cell RNA - OE19 [nTPM]":"47.7","Cell RNA - PC-3 [nTPM]":"88.5","Cell RNA - REH [nTPM]":"49.3","Cell RNA - RH-30 [nTPM]":"32.9","Cell RNA - RPMI-8226 [nTPM]":"53.8","Cell RNA - RPTEC TERT1 [nTPM]":"49.1","Cell RNA - RT4 [nTPM]":"63.4","Cell RNA - SCLC-21H [nTPM]":"17.6","Cell RNA - SH-SY5Y [nTPM]":"41.6","Cell RNA - SiHa [nTPM]":"114.8","Cell RNA - SK-BR-3 [nTPM]":"29.8","Cell RNA - SK-MEL-30 [nTPM]":"27.6","Cell RNA - SuSa [nTPM]":"57.6","Cell RNA - T-47d [nTPM]":"14.8","Cell RNA - THP-1 [nTPM]":"54.5","Cell RNA - TIME [nTPM]":"82.6","Cell RNA - U-138 MG [nTPM]":"40.2","Cell RNA - U-2 OS [nTPM]":"59.0","Cell RNA - U-2197 [nTPM]":"43.3","Cell RNA - U-251 MG [nTPM]":"60.5","Cell RNA - U-266\/70 [nTPM]":"23.4","Cell RNA - U-266\/84 [nTPM]":"37.3","Cell RNA - U-698 [nTPM]":"58.9","Cell RNA - U-87 MG [nTPM]":"48.3","Cell RNA - U-937 [nTPM]":"51.1","Cell RNA - WM-115 [nTPM]":"50.0","Blood RNA - basophil [nTPM]":"112.3","Blood RNA - classical monocyte [nTPM]":"58.4","Blood RNA - eosinophil [nTPM]":"86.8","Blood RNA - gdT-cell [nTPM]":"57.1","Blood RNA - intermediate monocyte [nTPM]":"67.8","Blood RNA - MAIT T-cell [nTPM]":"37.4","Blood RNA - memory B-cell [nTPM]":"19.5","Blood RNA - memory CD4 T-cell [nTPM]":"33.2","Blood RNA - memory CD8 T-cell [nTPM]":"43.7","Blood RNA - myeloid DC [nTPM]":"54.8","Blood RNA - naive B-cell [nTPM]":"13.4","Blood RNA - naive CD4 T-cell [nTPM]":"20.3","Blood RNA - naive CD8 T-cell [nTPM]":"36.7","Blood RNA - neutrophil [nTPM]":"162.2","Blood RNA - NK-cell [nTPM]":"45.5","Blood RNA - non-classical monocyte [nTPM]":"95.5","Blood RNA - plasmacytoid DC [nTPM]":"23.8","Blood RNA - T-reg [nTPM]":"45.1","Blood RNA - total PBMC [nTPM]":"32.4","Brain RNA - amygdala [nTPM]":"24.0","Brain RNA - basal ganglia [nTPM]":"23.4","Brain RNA - cerebellum [nTPM]":"22.4","Brain RNA - cerebral cortex [nTPM]":"26.2","Brain RNA - hippocampal formation [nTPM]":"23.6","Brain RNA - hypothalamus [nTPM]":"25.8","Brain RNA - medulla oblongata [nTPM]":"26.5","Brain RNA - midbrain [nTPM]":"24.9","Brain RNA - pons [nTPM]":"26.3","Brain RNA - spinal cord [nTPM]":"23.8","Brain RNA - thalamus [nTPM]":"25.7","Brain RNA - white matter [nTPM]":"23.5","Single Cell Type RNA - Adipocytes [nTPM]":"12.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.2","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"12.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.1","Single Cell Type RNA - Bipolar cells [nTPM]":"3.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"12.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"29.3","Single Cell Type RNA - dendritic cells [nTPM]":"33.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"30.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"39.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.7","Single Cell Type RNA - Endothelial cells [nTPM]":"13.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.6","Single Cell Type RNA - Erythroid cells [nTPM]":"9.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"46.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"55.3","Single Cell Type RNA - Fibroblasts [nTPM]":"13.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.7","Single Cell Type RNA - granulocytes [nTPM]":"16.5","Single Cell Type RNA - Granulosa cells [nTPM]":"6.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.5","Single Cell Type RNA - Hepatocytes [nTPM]":"13.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"42.0","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.9","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"19.8","Single Cell Type RNA - Langerhans cells [nTPM]":"16.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"26.5","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"37.2","Single Cell Type RNA - Muller glia cells [nTPM]":"11.5","Single Cell Type RNA - NK-cells [nTPM]":"48.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"49.7","Single Cell Type RNA - Paneth cells [nTPM]":"20.0","Single Cell Type RNA - Peritubular cells [nTPM]":"11.7","Single Cell Type RNA - Plasma cells [nTPM]":"16.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.3","Single Cell Type RNA - Spermatocytes [nTPM]":"12.6","Single Cell Type RNA - Spermatogonia [nTPM]":"22.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.5","Single Cell Type RNA - T-cells [nTPM]":"24.3","Single Cell Type RNA - Theca cells [nTPM]":"13.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.2","Single Cell Type RNA - Urothelial cells [nTPM]":"15.2"},{"Gene":"UVSSA","Gene synonym":["KIAA1530"],"Ensembl":"ENSG00000163945","Gene description":"UV stimulated scaffold protein A","Uniprot":["Q2YD98"],"Chromosome":"4","Position":"1345691-1395989","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":null,"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"NK-cell":"3.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050824","HPA053496"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA050824":"AB_2681251","HPA053496":"AB_2682170"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.40e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.90e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.87e-4"},"Tissue RNA - adipose tissue [nTPM]":"4.2","Tissue RNA - adrenal gland [nTPM]":"4.3","Tissue RNA - amygdala [nTPM]":"3.5","Tissue RNA - appendix [nTPM]":"5.5","Tissue RNA - basal ganglia [nTPM]":"4.1","Tissue RNA - bone marrow [nTPM]":"8.0","Tissue RNA - breast [nTPM]":"4.4","Tissue RNA - cerebellum [nTPM]":"3.4","Tissue RNA - cerebral cortex [nTPM]":"5.1","Tissue RNA - cervix [nTPM]":"4.5","Tissue RNA - choroid plexus [nTPM]":"5.5","Tissue RNA - colon [nTPM]":"4.7","Tissue RNA - duodenum [nTPM]":"5.5","Tissue RNA - endometrium 1 [nTPM]":"5.0","Tissue RNA - epididymis [nTPM]":"6.0","Tissue RNA - esophagus [nTPM]":"4.2","Tissue RNA - fallopian tube [nTPM]":"6.4","Tissue RNA - gallbladder [nTPM]":"3.4","Tissue RNA - heart muscle [nTPM]":"2.9","Tissue RNA - hippocampal formation [nTPM]":"3.3","Tissue RNA - hypothalamus [nTPM]":"3.1","Tissue RNA - kidney [nTPM]":"3.2","Tissue RNA - liver [nTPM]":"3.9","Tissue RNA - lung [nTPM]":"6.0","Tissue RNA - lymph node [nTPM]":"3.8","Tissue RNA - medulla oblongata [nTPM]":"5.7","Tissue RNA - midbrain [nTPM]":"3.9","Tissue RNA - ovary [nTPM]":"5.5","Tissue RNA - pancreas [nTPM]":"6.7","Tissue RNA - parathyroid gland [nTPM]":"2.6","Tissue RNA - pituitary gland [nTPM]":"9.3","Tissue RNA - placenta [nTPM]":"2.8","Tissue RNA - pons [nTPM]":"4.7","Tissue RNA - prostate [nTPM]":"4.1","Tissue RNA - rectum [nTPM]":"3.5","Tissue RNA - retina [nTPM]":"4.7","Tissue RNA - salivary gland [nTPM]":"5.7","Tissue RNA - seminal vesicle [nTPM]":"2.7","Tissue RNA - skeletal muscle [nTPM]":"4.6","Tissue RNA - skin 1 [nTPM]":"9.2","Tissue RNA - small intestine [nTPM]":"5.3","Tissue RNA - smooth muscle [nTPM]":"2.5","Tissue RNA - spinal cord [nTPM]":"3.0","Tissue RNA - spleen [nTPM]":"5.6","Tissue RNA - stomach 1 [nTPM]":"5.5","Tissue RNA - testis [nTPM]":"9.4","Tissue RNA - thalamus [nTPM]":"5.4","Tissue RNA - thymus [nTPM]":"3.8","Tissue RNA - thyroid gland [nTPM]":"7.1","Tissue RNA - tongue [nTPM]":"1.5","Tissue RNA - tonsil [nTPM]":"3.4","Tissue RNA - urinary bladder [nTPM]":"4.7","Tissue RNA - vagina [nTPM]":"4.5","Tissue RNA - white matter [nTPM]":"7.5","Cell RNA - A-431 [nTPM]":"3.7","Cell RNA - A549 [nTPM]":"4.1","Cell RNA - AF22 [nTPM]":"6.1","Cell RNA - AN3-CA [nTPM]":"5.7","Cell RNA - ASC diff [nTPM]":"7.0","Cell RNA - ASC TERT1 [nTPM]":"9.0","Cell RNA - BEWO [nTPM]":"4.6","Cell RNA - BJ [nTPM]":"3.4","Cell RNA - BJ hTERT+ [nTPM]":"2.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.6","Cell RNA - CACO-2 [nTPM]":"3.4","Cell RNA - CAPAN-2 [nTPM]":"7.5","Cell RNA - Daudi [nTPM]":"2.7","Cell RNA - EFO-21 [nTPM]":"6.5","Cell RNA - fHDF\/TERT166 [nTPM]":"3.4","Cell RNA - GAMG [nTPM]":"7.9","Cell RNA - HaCaT [nTPM]":"4.4","Cell RNA - HAP1 [nTPM]":"3.8","Cell RNA - HBEC3-KT [nTPM]":"3.9","Cell RNA - HBF TERT88 [nTPM]":"2.6","Cell RNA - HDLM-2 [nTPM]":"3.7","Cell RNA - HEK 293 [nTPM]":"1.6","Cell RNA - HEL [nTPM]":"6.4","Cell RNA - HeLa [nTPM]":"7.9","Cell RNA - Hep G2 [nTPM]":"4.0","Cell RNA - HHSteC [nTPM]":"2.7","Cell RNA - HL-60 [nTPM]":"3.9","Cell RNA - HMC-1 [nTPM]":"7.6","Cell RNA - HSkMC [nTPM]":"2.6","Cell RNA - hTCEpi [nTPM]":"7.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.4","Cell RNA - hTERT-HME1 [nTPM]":"4.4","Cell RNA - hTERT-RPE1 [nTPM]":"3.4","Cell RNA - HUVEC TERT2 [nTPM]":"5.0","Cell RNA - JURKAT [nTPM]":"4.6","Cell RNA - K-562 [nTPM]":"6.2","Cell RNA - Karpas-707 [nTPM]":"8.9","Cell RNA - LHCN-M2 [nTPM]":"3.7","Cell RNA - MCF7 [nTPM]":"2.1","Cell RNA - MOLT-4 [nTPM]":"5.8","Cell RNA - NB-4 [nTPM]":"8.1","Cell RNA - NTERA-2 [nTPM]":"6.0","Cell RNA - OE19 [nTPM]":"2.9","Cell RNA - PC-3 [nTPM]":"5.2","Cell RNA - REH [nTPM]":"5.0","Cell RNA - RH-30 [nTPM]":"3.1","Cell RNA - RPMI-8226 [nTPM]":"3.4","Cell RNA - RPTEC TERT1 [nTPM]":"2.7","Cell RNA - RT4 [nTPM]":"5.4","Cell RNA - SCLC-21H [nTPM]":"4.4","Cell RNA - SH-SY5Y [nTPM]":"5.8","Cell RNA - SiHa [nTPM]":"2.6","Cell RNA - SK-BR-3 [nTPM]":"3.0","Cell RNA - SK-MEL-30 [nTPM]":"3.8","Cell RNA - SuSa [nTPM]":"5.3","Cell RNA - T-47d [nTPM]":"8.0","Cell RNA - THP-1 [nTPM]":"2.2","Cell RNA - TIME [nTPM]":"9.5","Cell RNA - U-138 MG [nTPM]":"11.4","Cell RNA - U-2 OS [nTPM]":"2.8","Cell RNA - U-2197 [nTPM]":"4.2","Cell RNA - U-251 MG [nTPM]":"5.9","Cell RNA - U-266\/70 [nTPM]":"13.4","Cell RNA - U-266\/84 [nTPM]":"9.0","Cell RNA - U-698 [nTPM]":"6.1","Cell RNA - U-87 MG [nTPM]":"8.5","Cell RNA - U-937 [nTPM]":"4.4","Cell RNA - WM-115 [nTPM]":"6.9","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.9","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"1.0","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"3.3","Blood RNA - non-classical monocyte [nTPM]":"0.8","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"3.5","Brain RNA - basal ganglia [nTPM]":"4.1","Brain RNA - cerebellum [nTPM]":"3.4","Brain RNA - cerebral cortex [nTPM]":"5.1","Brain RNA - hippocampal formation [nTPM]":"3.3","Brain RNA - hypothalamus [nTPM]":"3.1","Brain RNA - medulla oblongata [nTPM]":"5.7","Brain RNA - midbrain [nTPM]":"3.9","Brain RNA - pons [nTPM]":"4.7","Brain RNA - spinal cord [nTPM]":"3.0","Brain RNA - thalamus [nTPM]":"5.4","Brain RNA - white matter [nTPM]":"7.5","Single Cell Type RNA - Adipocytes [nTPM]":"20.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.2","Single Cell Type RNA - Astrocytes [nTPM]":"16.3","Single Cell Type RNA - B-cells [nTPM]":"11.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"18.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"8.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - dendritic cells [nTPM]":"17.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.0","Single Cell Type RNA - Early spermatids [nTPM]":"7.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.1","Single Cell Type RNA - Endothelial cells [nTPM]":"9.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.9","Single Cell Type RNA - Fibroblasts [nTPM]":"10.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.1","Single Cell Type RNA - granulocytes [nTPM]":"8.8","Single Cell Type RNA - Granulosa cells [nTPM]":"16.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"12.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.8","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.9","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"10.8","Single Cell Type RNA - Langerhans cells [nTPM]":"6.3","Single Cell Type RNA - Late spermatids [nTPM]":"7.3","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"13.4","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"7.6","Single Cell Type RNA - Muller glia cells [nTPM]":"9.0","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.1","Single Cell Type RNA - Paneth cells [nTPM]":"6.7","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"12.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.4","Single Cell Type RNA - Spermatocytes [nTPM]":"23.2","Single Cell Type RNA - Spermatogonia [nTPM]":"9.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.7","Single Cell Type RNA - T-cells [nTPM]":"12.0","Single Cell Type RNA - Theca cells [nTPM]":"12.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"6.5","Single Cell Type RNA - Urothelial cells [nTPM]":"4.5"},{"Gene":"ZNF750","Gene synonym":["FLJ13841","Zfp750"],"Ensembl":"ENSG00000141579","Gene description":"Zinc finger protein 750","Uniprot":["Q32MQ0"],"Chromosome":"17","Position":"82829434-82840022","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Differentiation","Transcription","Transcription regulation"],"Molecular function":["Activator"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"96.1","skin 1":"139.0","vagina":"51.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"33.3","Squamous epithelial cells":"156.8","Suprabasal keratinocytes":"41.1","Syncytiotrophoblasts":"68.1","Urothelial cells":"51.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"20.5","head and neck cancer":"24.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"18.3","hTCEpi":"7.2","MCF7":"5.4","SK-BR-3":"14.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021573","HPA023012"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 11: Squamous epithelial cells - Epithelial cell function","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 61: Squamous epithelial cells - Keratinization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA021573":"AB_1859438","HPA023012":"AB_1859439"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.48e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.55e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.30e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.30e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"1.2","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"5.1","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"0.9","Tissue RNA - cervix [nTPM]":"25.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"4.1","Tissue RNA - esophagus [nTPM]":"96.1","Tissue RNA - fallopian tube [nTPM]":"0.6","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.6","Tissue RNA - hippocampal formation [nTPM]":"0.6","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"2.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"1.0","Tissue RNA - midbrain [nTPM]":"0.3","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"2.2","Tissue RNA - pituitary gland [nTPM]":"2.9","Tissue RNA - placenta [nTPM]":"3.9","Tissue RNA - pons [nTPM]":"1.0","Tissue RNA - prostate [nTPM]":"3.3","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"33.6","Tissue RNA - seminal vesicle [nTPM]":"2.7","Tissue RNA - skeletal muscle [nTPM]":"12.0","Tissue RNA - skin 1 [nTPM]":"139.0","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"5.1","Tissue RNA - thyroid gland [nTPM]":"3.5","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"14.7","Tissue RNA - urinary bladder [nTPM]":"4.9","Tissue RNA - vagina [nTPM]":"51.7","Tissue RNA - white matter [nTPM]":"2.3","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"18.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.7","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"7.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"5.4","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"3.3","Cell RNA - SCLC-21H [nTPM]":"1.2","Cell RNA - SH-SY5Y [nTPM]":"1.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"14.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.7","Cell RNA - T-47d [nTPM]":"2.3","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"1.2","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"0.9","Brain RNA - hippocampal formation [nTPM]":"0.6","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"1.0","Brain RNA - midbrain [nTPM]":"0.3","Brain RNA - pons [nTPM]":"1.0","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"2.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"21.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.9","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"33.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.8","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"156.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"41.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"68.1","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"51.3"}]