[{"Gene":"BRAF","Gene synonym":["BRAF1"],"Ensembl":"ENSG00000157764","Gene description":"B-Raf proto-oncogene, serine\/threonine kinase","Uniprot":["P15056"],"Chromosome":"7","Position":"140719327-140924929","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Allosteric enzyme","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Cardiomyopathy","Deafness","Disease variant","Ectodermal dysplasia","FDA approved drug targets","Mental retardation","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"252.3","Inhibitory neurons":"242.4","Oligodendrocyte precursor cells":"206.1","Oligodendrocytes":"202.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001328","CAB004552","HPA071048"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004552":"AB_626760","HPA001328":"AB_1078296","HPA071048":"AB_2686336"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.8","Tissue RNA - adrenal gland [nTPM]":"5.8","Tissue RNA - amygdala [nTPM]":"6.3","Tissue RNA - appendix [nTPM]":"5.6","Tissue RNA - basal ganglia [nTPM]":"7.7","Tissue RNA - bone marrow [nTPM]":"15.9","Tissue RNA - breast [nTPM]":"8.8","Tissue RNA - cerebellum [nTPM]":"12.5","Tissue RNA - cerebral cortex [nTPM]":"8.7","Tissue RNA - cervix [nTPM]":"8.2","Tissue RNA - choroid plexus [nTPM]":"5.4","Tissue RNA - colon [nTPM]":"8.6","Tissue RNA - duodenum [nTPM]":"4.7","Tissue RNA - endometrium 1 [nTPM]":"8.3","Tissue RNA - epididymis [nTPM]":"8.3","Tissue RNA - esophagus [nTPM]":"7.5","Tissue RNA - fallopian tube [nTPM]":"8.0","Tissue RNA - gallbladder [nTPM]":"5.8","Tissue RNA - heart muscle [nTPM]":"7.6","Tissue RNA - hippocampal formation [nTPM]":"8.3","Tissue RNA - hypothalamus [nTPM]":"6.7","Tissue RNA - kidney [nTPM]":"7.6","Tissue RNA - liver [nTPM]":"6.6","Tissue RNA - lung [nTPM]":"9.9","Tissue RNA - lymph node [nTPM]":"6.9","Tissue RNA - medulla oblongata [nTPM]":"4.0","Tissue RNA - midbrain [nTPM]":"3.6","Tissue RNA - ovary [nTPM]":"9.8","Tissue RNA - pancreas [nTPM]":"8.3","Tissue RNA - parathyroid gland [nTPM]":"11.5","Tissue RNA - pituitary gland [nTPM]":"9.0","Tissue RNA - placenta [nTPM]":"7.2","Tissue RNA - pons [nTPM]":"4.6","Tissue RNA - prostate [nTPM]":"8.2","Tissue RNA - rectum [nTPM]":"5.4","Tissue RNA - retina [nTPM]":"17.0","Tissue RNA - salivary gland [nTPM]":"7.2","Tissue RNA - seminal vesicle [nTPM]":"5.9","Tissue RNA - skeletal muscle [nTPM]":"8.6","Tissue RNA - skin 1 [nTPM]":"10.4","Tissue RNA - small intestine [nTPM]":"6.9","Tissue RNA - smooth muscle [nTPM]":"6.0","Tissue RNA - spinal cord [nTPM]":"3.1","Tissue RNA - spleen [nTPM]":"6.7","Tissue RNA - stomach 1 [nTPM]":"7.8","Tissue RNA - testis [nTPM]":"13.7","Tissue RNA - thalamus [nTPM]":"5.2","Tissue RNA - thymus [nTPM]":"8.7","Tissue RNA - thyroid gland [nTPM]":"10.2","Tissue RNA - tongue [nTPM]":"8.4","Tissue RNA - tonsil [nTPM]":"6.4","Tissue RNA - urinary bladder [nTPM]":"9.9","Tissue RNA - vagina [nTPM]":"8.5","Tissue RNA - white matter [nTPM]":"6.7","Cell RNA - A-431 [nTPM]":"6.3","Cell RNA - A549 [nTPM]":"5.2","Cell RNA - AF22 [nTPM]":"7.7","Cell RNA - AN3-CA [nTPM]":"9.4","Cell RNA - ASC diff [nTPM]":"9.1","Cell RNA - ASC TERT1 [nTPM]":"11.8","Cell RNA - BEWO [nTPM]":"12.3","Cell RNA - BJ [nTPM]":"6.8","Cell RNA - BJ hTERT+ [nTPM]":"7.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.6","Cell RNA - CACO-2 [nTPM]":"5.7","Cell RNA - CAPAN-2 [nTPM]":"6.7","Cell RNA - Daudi [nTPM]":"10.8","Cell RNA - EFO-21 [nTPM]":"5.0","Cell RNA - fHDF\/TERT166 [nTPM]":"7.3","Cell RNA - GAMG [nTPM]":"8.4","Cell RNA - HaCaT [nTPM]":"3.4","Cell RNA - HAP1 [nTPM]":"6.8","Cell RNA - HBEC3-KT [nTPM]":"5.5","Cell RNA - HBF TERT88 [nTPM]":"10.0","Cell RNA - HDLM-2 [nTPM]":"9.8","Cell RNA - HEK 293 [nTPM]":"5.4","Cell RNA - HEL [nTPM]":"7.1","Cell RNA - HeLa [nTPM]":"5.1","Cell RNA - Hep G2 [nTPM]":"5.2","Cell RNA - HHSteC [nTPM]":"7.6","Cell RNA - HL-60 [nTPM]":"11.7","Cell RNA - HMC-1 [nTPM]":"6.8","Cell RNA - HSkMC [nTPM]":"7.9","Cell RNA - hTCEpi [nTPM]":"6.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.0","Cell RNA - hTERT-HME1 [nTPM]":"12.0","Cell RNA - hTERT-RPE1 [nTPM]":"8.2","Cell RNA - HUVEC TERT2 [nTPM]":"6.6","Cell RNA - JURKAT [nTPM]":"7.7","Cell RNA - K-562 [nTPM]":"11.3","Cell RNA - Karpas-707 [nTPM]":"19.1","Cell RNA - LHCN-M2 [nTPM]":"9.8","Cell RNA - MCF7 [nTPM]":"3.3","Cell RNA - MOLT-4 [nTPM]":"15.6","Cell RNA - NB-4 [nTPM]":"12.0","Cell RNA - NTERA-2 [nTPM]":"6.9","Cell RNA - OE19 [nTPM]":"6.2","Cell RNA - PC-3 [nTPM]":"3.1","Cell RNA - REH [nTPM]":"10.1","Cell RNA - RH-30 [nTPM]":"6.5","Cell RNA - RPMI-8226 [nTPM]":"8.9","Cell RNA - RPTEC TERT1 [nTPM]":"5.3","Cell RNA - RT4 [nTPM]":"11.9","Cell RNA - SCLC-21H [nTPM]":"8.9","Cell RNA - SH-SY5Y [nTPM]":"7.3","Cell RNA - SiHa [nTPM]":"7.9","Cell RNA - SK-BR-3 [nTPM]":"4.9","Cell RNA - SK-MEL-30 [nTPM]":"7.3","Cell RNA - SuSa [nTPM]":"7.5","Cell RNA - T-47d [nTPM]":"4.5","Cell RNA - THP-1 [nTPM]":"7.8","Cell RNA - TIME [nTPM]":"9.7","Cell RNA - U-138 MG [nTPM]":"5.9","Cell RNA - U-2 OS [nTPM]":"4.3","Cell RNA - U-2197 [nTPM]":"12.9","Cell RNA - U-251 MG [nTPM]":"5.5","Cell RNA - U-266\/70 [nTPM]":"21.6","Cell RNA - U-266\/84 [nTPM]":"12.9","Cell RNA - U-698 [nTPM]":"16.7","Cell RNA - U-87 MG [nTPM]":"9.7","Cell RNA - U-937 [nTPM]":"11.3","Cell RNA - WM-115 [nTPM]":"6.6","Blood RNA - basophil [nTPM]":"1.9","Blood RNA - classical monocyte [nTPM]":"1.0","Blood RNA - eosinophil [nTPM]":"4.1","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.2","Blood RNA - myeloid DC [nTPM]":"0.8","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"2.0","Blood RNA - NK-cell [nTPM]":"3.5","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"1.5","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"6.3","Brain RNA - basal ganglia [nTPM]":"7.7","Brain RNA - cerebellum [nTPM]":"12.5","Brain RNA - cerebral cortex [nTPM]":"8.7","Brain RNA - hippocampal formation [nTPM]":"8.3","Brain RNA - hypothalamus [nTPM]":"6.7","Brain RNA - medulla oblongata [nTPM]":"4.0","Brain RNA - midbrain [nTPM]":"3.6","Brain RNA - pons [nTPM]":"4.6","Brain RNA - spinal cord [nTPM]":"3.1","Brain RNA - thalamus [nTPM]":"5.2","Brain RNA - white matter [nTPM]":"6.7","Single Cell Type RNA - Adipocytes [nTPM]":"43.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"45.7","Single Cell Type RNA - Astrocytes [nTPM]":"151.1","Single Cell Type RNA - B-cells [nTPM]":"58.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"21.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.3","Single Cell Type RNA - Bipolar cells [nTPM]":"29.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"31.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"18.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.7","Single Cell Type RNA - dendritic cells [nTPM]":"73.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"14.3","Single Cell Type RNA - Early spermatids [nTPM]":"68.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"50.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.4","Single Cell Type RNA - Endothelial cells [nTPM]":"23.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.2","Single Cell Type RNA - Erythroid cells [nTPM]":"14.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"252.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.9","Single Cell Type RNA - Fibroblasts [nTPM]":"22.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"69.2","Single Cell Type RNA - granulocytes [nTPM]":"24.7","Single Cell Type RNA - Granulosa cells [nTPM]":"45.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.3","Single Cell Type RNA - Hepatocytes [nTPM]":"9.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.4","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"242.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.8","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"13.6","Single Cell Type RNA - Langerhans cells [nTPM]":"37.1","Single Cell Type RNA - Late spermatids [nTPM]":"36.5","Single Cell Type RNA - Leydig cells [nTPM]":"16.4","Single Cell Type RNA - Macrophages [nTPM]":"30.1","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"126.5","Single Cell Type RNA - monocytes [nTPM]":"14.6","Single Cell Type RNA - Muller glia cells [nTPM]":"11.3","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"206.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"202.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.4","Single Cell Type RNA - Paneth cells [nTPM]":"8.1","Single Cell Type RNA - Peritubular cells [nTPM]":"10.1","Single Cell Type RNA - Plasma cells [nTPM]":"48.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"33.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"24.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.7","Single Cell Type RNA - Spermatocytes [nTPM]":"43.8","Single Cell Type RNA - Spermatogonia [nTPM]":"26.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"75.5","Single Cell Type RNA - T-cells [nTPM]":"41.4","Single Cell Type RNA - Theca cells [nTPM]":"30.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.7","Single Cell Type RNA - Urothelial cells [nTPM]":"33.4"},{"Gene":"CDK4","Gene synonym":["PSK-J3"],"Ensembl":"ENSG00000135446","Gene description":"Cyclin dependent kinase 4","Uniprot":["P11802"],"Chromosome":"12","Position":"57747727-57756013","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"175.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"HBEC3-KT":"2594.8","LHCN-M2":"2819.4","RH-30":"8902.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006024","CAB013116","CAB069405"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Nuclear membrane","Nucleoli"],"Antibody RRID":{"CAB013116":"AB_2536376","CAB069405":"AB_1613464","HPA006024":"AB_2667497"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.09e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.15e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Tissue RNA - adipose tissue [nTPM]":"69.7","Tissue RNA - adrenal gland [nTPM]":"87.8","Tissue RNA - amygdala [nTPM]":"35.0","Tissue RNA - appendix [nTPM]":"52.8","Tissue RNA - basal ganglia [nTPM]":"37.9","Tissue RNA - bone marrow [nTPM]":"72.0","Tissue RNA - breast [nTPM]":"76.6","Tissue RNA - cerebellum [nTPM]":"37.7","Tissue RNA - cerebral cortex [nTPM]":"36.9","Tissue RNA - cervix [nTPM]":"84.3","Tissue RNA - choroid plexus [nTPM]":"35.9","Tissue RNA - colon [nTPM]":"62.6","Tissue RNA - duodenum [nTPM]":"40.2","Tissue RNA - endometrium 1 [nTPM]":"97.4","Tissue RNA - epididymis [nTPM]":"64.2","Tissue RNA - esophagus [nTPM]":"57.2","Tissue RNA - fallopian tube [nTPM]":"69.4","Tissue RNA - gallbladder [nTPM]":"57.1","Tissue RNA - heart muscle [nTPM]":"58.9","Tissue RNA - hippocampal formation [nTPM]":"33.6","Tissue RNA - hypothalamus [nTPM]":"37.1","Tissue RNA - kidney [nTPM]":"58.5","Tissue RNA - liver [nTPM]":"51.5","Tissue RNA - lung [nTPM]":"58.0","Tissue RNA - lymph node [nTPM]":"66.8","Tissue RNA - medulla oblongata [nTPM]":"37.1","Tissue RNA - midbrain [nTPM]":"36.9","Tissue RNA - ovary [nTPM]":"97.3","Tissue RNA - pancreas [nTPM]":"70.9","Tissue RNA - parathyroid gland [nTPM]":"63.5","Tissue RNA - pituitary gland [nTPM]":"67.7","Tissue RNA - placenta [nTPM]":"52.4","Tissue RNA - pons [nTPM]":"36.8","Tissue RNA - prostate [nTPM]":"52.7","Tissue RNA - rectum [nTPM]":"63.3","Tissue RNA - retina [nTPM]":"14.5","Tissue RNA - salivary gland [nTPM]":"54.4","Tissue RNA - seminal vesicle [nTPM]":"54.1","Tissue RNA - skeletal muscle [nTPM]":"48.2","Tissue RNA - skin 1 [nTPM]":"58.9","Tissue RNA - small intestine [nTPM]":"47.2","Tissue RNA - smooth muscle [nTPM]":"80.4","Tissue RNA - spinal cord [nTPM]":"37.3","Tissue RNA - spleen [nTPM]":"51.5","Tissue RNA - stomach 1 [nTPM]":"54.8","Tissue RNA - testis [nTPM]":"24.1","Tissue RNA - thalamus [nTPM]":"37.3","Tissue RNA - thymus [nTPM]":"67.6","Tissue RNA - thyroid gland [nTPM]":"66.0","Tissue RNA - tongue [nTPM]":"52.7","Tissue RNA - tonsil [nTPM]":"70.6","Tissue RNA - urinary bladder [nTPM]":"71.6","Tissue RNA - vagina [nTPM]":"60.7","Tissue RNA - white matter [nTPM]":"37.6","Cell RNA - A-431 [nTPM]":"207.1","Cell RNA - A549 [nTPM]":"235.7","Cell RNA - AF22 [nTPM]":"295.7","Cell RNA - AN3-CA [nTPM]":"268.0","Cell RNA - ASC diff [nTPM]":"253.7","Cell RNA - ASC TERT1 [nTPM]":"220.7","Cell RNA - BEWO [nTPM]":"210.4","Cell RNA - BJ [nTPM]":"116.1","Cell RNA - BJ hTERT+ [nTPM]":"347.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"468.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"385.7","Cell RNA - CACO-2 [nTPM]":"338.2","Cell RNA - CAPAN-2 [nTPM]":"189.1","Cell RNA - Daudi [nTPM]":"297.4","Cell RNA - EFO-21 [nTPM]":"200.2","Cell RNA - fHDF\/TERT166 [nTPM]":"173.6","Cell RNA - GAMG [nTPM]":"293.2","Cell RNA - HaCaT [nTPM]":"158.0","Cell RNA - HAP1 [nTPM]":"396.3","Cell RNA - HBEC3-KT [nTPM]":"2594.8","Cell RNA - HBF TERT88 [nTPM]":"354.9","Cell RNA - HDLM-2 [nTPM]":"150.9","Cell RNA - HEK 293 [nTPM]":"209.0","Cell RNA - HEL [nTPM]":"275.4","Cell RNA - HeLa [nTPM]":"149.5","Cell RNA - Hep G2 [nTPM]":"237.9","Cell RNA - HHSteC [nTPM]":"297.0","Cell RNA - HL-60 [nTPM]":"309.7","Cell RNA - HMC-1 [nTPM]":"182.5","Cell RNA - HSkMC [nTPM]":"221.5","Cell RNA - hTCEpi [nTPM]":"180.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"294.2","Cell RNA - hTERT-HME1 [nTPM]":"326.7","Cell RNA - hTERT-RPE1 [nTPM]":"326.4","Cell RNA - HUVEC TERT2 [nTPM]":"304.8","Cell RNA - JURKAT [nTPM]":"280.0","Cell RNA - K-562 [nTPM]":"301.3","Cell RNA - Karpas-707 [nTPM]":"242.7","Cell RNA - LHCN-M2 [nTPM]":"2819.4","Cell RNA - MCF7 [nTPM]":"304.9","Cell RNA - MOLT-4 [nTPM]":"296.7","Cell RNA - NB-4 [nTPM]":"256.5","Cell RNA - NTERA-2 [nTPM]":"347.0","Cell RNA - OE19 [nTPM]":"208.0","Cell RNA - PC-3 [nTPM]":"249.8","Cell RNA - REH [nTPM]":"267.3","Cell RNA - RH-30 [nTPM]":"8902.5","Cell RNA - RPMI-8226 [nTPM]":"272.1","Cell RNA - RPTEC TERT1 [nTPM]":"147.2","Cell RNA - RT4 [nTPM]":"320.6","Cell RNA - SCLC-21H [nTPM]":"271.2","Cell RNA - SH-SY5Y [nTPM]":"251.7","Cell RNA - SiHa [nTPM]":"205.3","Cell RNA - SK-BR-3 [nTPM]":"150.2","Cell RNA - SK-MEL-30 [nTPM]":"310.0","Cell RNA - SuSa [nTPM]":"195.1","Cell RNA - T-47d [nTPM]":"202.8","Cell RNA - THP-1 [nTPM]":"380.7","Cell RNA - TIME [nTPM]":"146.1","Cell RNA - U-138 MG [nTPM]":"233.6","Cell RNA - U-2 OS [nTPM]":"217.0","Cell RNA - U-2197 [nTPM]":"265.8","Cell RNA - U-251 MG [nTPM]":"233.1","Cell RNA - U-266\/70 [nTPM]":"122.2","Cell RNA - U-266\/84 [nTPM]":"206.1","Cell RNA - U-698 [nTPM]":"450.8","Cell RNA - U-87 MG [nTPM]":"214.1","Cell RNA - U-937 [nTPM]":"291.3","Cell RNA - WM-115 [nTPM]":"286.9","Blood RNA - basophil [nTPM]":"9.5","Blood RNA - classical monocyte [nTPM]":"46.5","Blood RNA - eosinophil [nTPM]":"10.3","Blood RNA - gdT-cell [nTPM]":"79.6","Blood RNA - intermediate monocyte [nTPM]":"65.6","Blood RNA - MAIT T-cell [nTPM]":"81.8","Blood RNA - memory B-cell [nTPM]":"93.5","Blood RNA - memory CD4 T-cell [nTPM]":"70.0","Blood RNA - memory CD8 T-cell [nTPM]":"72.5","Blood RNA - myeloid DC [nTPM]":"66.7","Blood RNA - naive B-cell [nTPM]":"90.0","Blood RNA - naive CD4 T-cell [nTPM]":"93.0","Blood RNA - naive CD8 T-cell [nTPM]":"84.4","Blood RNA - neutrophil [nTPM]":"4.4","Blood RNA - NK-cell [nTPM]":"56.6","Blood RNA - non-classical monocyte [nTPM]":"41.9","Blood RNA - plasmacytoid DC [nTPM]":"84.9","Blood RNA - T-reg [nTPM]":"57.0","Blood RNA - total PBMC [nTPM]":"73.6","Brain RNA - amygdala [nTPM]":"35.0","Brain RNA - basal ganglia [nTPM]":"37.9","Brain RNA - cerebellum [nTPM]":"37.7","Brain RNA - cerebral cortex [nTPM]":"36.9","Brain RNA - hippocampal formation [nTPM]":"33.6","Brain RNA - hypothalamus [nTPM]":"37.1","Brain RNA - medulla oblongata [nTPM]":"37.1","Brain RNA - midbrain [nTPM]":"36.9","Brain RNA - pons [nTPM]":"36.8","Brain RNA - spinal cord [nTPM]":"37.3","Brain RNA - thalamus [nTPM]":"37.3","Brain RNA - white matter [nTPM]":"37.6","Single Cell Type RNA - Adipocytes [nTPM]":"47.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.8","Single Cell Type RNA - Astrocytes [nTPM]":"7.8","Single Cell Type RNA - B-cells [nTPM]":"40.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"89.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"78.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"83.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"74.0","Single Cell Type RNA - Bipolar cells [nTPM]":"15.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"67.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"82.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"51.5","Single Cell Type RNA - Club cells [nTPM]":"35.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"82.9","Single Cell Type RNA - dendritic cells [nTPM]":"26.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"70.5","Single Cell Type RNA - Ductal cells [nTPM]":"93.1","Single Cell Type RNA - Early spermatids [nTPM]":"13.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"77.7","Single Cell Type RNA - Endothelial cells [nTPM]":"50.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"45.6","Single Cell Type RNA - Erythroid cells [nTPM]":"98.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"62.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"134.5","Single Cell Type RNA - Fibroblasts [nTPM]":"79.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"22.6","Single Cell Type RNA - granulocytes [nTPM]":"69.1","Single Cell Type RNA - Granulosa cells [nTPM]":"60.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"39.7","Single Cell Type RNA - Hepatocytes [nTPM]":"35.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"132.9","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"42.2","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"25.1","Single Cell Type RNA - Langerhans cells [nTPM]":"44.1","Single Cell Type RNA - Late spermatids [nTPM]":"8.0","Single Cell Type RNA - Leydig cells [nTPM]":"64.0","Single Cell Type RNA - Macrophages [nTPM]":"31.2","Single Cell Type RNA - Melanocytes [nTPM]":"53.4","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"41.9","Single Cell Type RNA - Muller glia cells [nTPM]":"51.4","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"48.3","Single Cell Type RNA - Paneth cells [nTPM]":"18.9","Single Cell Type RNA - Peritubular cells [nTPM]":"63.2","Single Cell Type RNA - Plasma cells [nTPM]":"57.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"113.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"80.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.9","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"62.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"61.9","Single Cell Type RNA - Spermatocytes [nTPM]":"32.1","Single Cell Type RNA - Spermatogonia [nTPM]":"48.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"74.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"86.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"46.8","Single Cell Type RNA - T-cells [nTPM]":"32.3","Single Cell Type RNA - Theca cells [nTPM]":"78.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"78.7","Single Cell Type RNA - Urothelial cells [nTPM]":"49.4"},{"Gene":"CDKN2A","Gene synonym":["ARF","CDK4I","CDKN2","CMM2","INK4","INK4a","MLM","MTS1","p14","p14ARF","p16","p16INK4a","p19","p19Arf"],"Ensembl":"ENSG00000147889","Gene description":"Cyclin dependent kinase inhibitor 2A","Uniprot":["P42771","Q8N726"],"Chromosome":"9","Position":"21967752-21995301","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis","Cell cycle","rRNA processing","Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Li-Fraumeni syndrome","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"31.7","pituitary gland":"33.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"170.1","Club cells":"145.9","Early spermatids":"227.5","Late spermatids":"447.9","Pancreatic endocrine cells":"417.7","Respiratory ciliated cells":"221.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"49.9","ovarian cancer":"57.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"37.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"15.6","T-cells":"37.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"289.2","HEK 293":"389.7","HeLa":"311.1","SK-MEL-30":"318.7"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000093","CAB000445","CAB018232","HPA047838"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"18000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 16: Pancreatic endocrine cells - Mixed function","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"CAB000093":"AB_442119","CAB000445":null,"CAB018232":"AB_785018","HPA047838":"AB_2680174"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.82e-7"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.19e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.17e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.76e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.7","Tissue RNA - adrenal gland [nTPM]":"10.1","Tissue RNA - amygdala [nTPM]":"7.4","Tissue RNA - appendix [nTPM]":"1.7","Tissue RNA - basal ganglia [nTPM]":"8.3","Tissue RNA - bone marrow [nTPM]":"1.3","Tissue RNA - breast [nTPM]":"3.1","Tissue RNA - cerebellum [nTPM]":"5.9","Tissue RNA - cerebral cortex [nTPM]":"8.5","Tissue RNA - cervix [nTPM]":"1.1","Tissue RNA - choroid plexus [nTPM]":"31.7","Tissue RNA - colon [nTPM]":"1.9","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"0.7","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"7.4","Tissue RNA - fallopian tube [nTPM]":"2.2","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"6.7","Tissue RNA - hypothalamus [nTPM]":"6.4","Tissue RNA - kidney [nTPM]":"0.5","Tissue RNA - liver [nTPM]":"0.7","Tissue RNA - lung [nTPM]":"2.3","Tissue RNA - lymph node [nTPM]":"2.1","Tissue RNA - medulla oblongata [nTPM]":"7.4","Tissue RNA - midbrain [nTPM]":"5.8","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"1.5","Tissue RNA - parathyroid gland [nTPM]":"2.1","Tissue RNA - pituitary gland [nTPM]":"33.7","Tissue RNA - placenta [nTPM]":"2.6","Tissue RNA - pons [nTPM]":"7.2","Tissue RNA - prostate [nTPM]":"2.1","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"1.6","Tissue RNA - seminal vesicle [nTPM]":"1.6","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"3.6","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"6.2","Tissue RNA - spleen [nTPM]":"5.5","Tissue RNA - stomach 1 [nTPM]":"3.9","Tissue RNA - testis [nTPM]":"14.8","Tissue RNA - thalamus [nTPM]":"8.0","Tissue RNA - thymus [nTPM]":"2.1","Tissue RNA - thyroid gland [nTPM]":"1.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"2.5","Tissue RNA - urinary bladder [nTPM]":"2.4","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"9.2","Cell RNA - A-431 [nTPM]":"11.8","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"1.7","Cell RNA - AN3-CA [nTPM]":"82.2","Cell RNA - ASC diff [nTPM]":"0.8","Cell RNA - ASC TERT1 [nTPM]":"0.9","Cell RNA - BEWO [nTPM]":"39.1","Cell RNA - BJ [nTPM]":"15.9","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"111.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"196.0","Cell RNA - CACO-2 [nTPM]":"19.1","Cell RNA - CAPAN-2 [nTPM]":"289.2","Cell RNA - Daudi [nTPM]":"47.1","Cell RNA - EFO-21 [nTPM]":"167.7","Cell RNA - fHDF\/TERT166 [nTPM]":"9.5","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"36.0","Cell RNA - HAP1 [nTPM]":"34.3","Cell RNA - HBEC3-KT [nTPM]":"211.0","Cell RNA - HBF TERT88 [nTPM]":"91.4","Cell RNA - HDLM-2 [nTPM]":"212.2","Cell RNA - HEK 293 [nTPM]":"389.7","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"311.1","Cell RNA - Hep G2 [nTPM]":"13.6","Cell RNA - HHSteC [nTPM]":"8.8","Cell RNA - HL-60 [nTPM]":"22.4","Cell RNA - HMC-1 [nTPM]":"17.3","Cell RNA - HSkMC [nTPM]":"21.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"112.2","Cell RNA - hTERT-HME1 [nTPM]":"61.9","Cell RNA - hTERT-RPE1 [nTPM]":"236.3","Cell RNA - HUVEC TERT2 [nTPM]":"11.7","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"188.4","Cell RNA - LHCN-M2 [nTPM]":"105.7","Cell RNA - MCF7 [nTPM]":"0.8","Cell RNA - MOLT-4 [nTPM]":"1.9","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"2.6","Cell RNA - OE19 [nTPM]":"24.2","Cell RNA - PC-3 [nTPM]":"185.9","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"80.2","Cell RNA - RPMI-8226 [nTPM]":"166.3","Cell RNA - RPTEC TERT1 [nTPM]":"23.4","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"195.2","Cell RNA - SH-SY5Y [nTPM]":"14.0","Cell RNA - SiHa [nTPM]":"219.9","Cell RNA - SK-BR-3 [nTPM]":"36.6","Cell RNA - SK-MEL-30 [nTPM]":"318.7","Cell RNA - SuSa [nTPM]":"9.4","Cell RNA - T-47d [nTPM]":"42.8","Cell RNA - THP-1 [nTPM]":"0.7","Cell RNA - TIME [nTPM]":"39.5","Cell RNA - U-138 MG [nTPM]":"0.9","Cell RNA - U-2 OS [nTPM]":"2.6","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"84.7","Cell RNA - U-266\/84 [nTPM]":"49.6","Cell RNA - U-698 [nTPM]":"177.8","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"62.9","Cell RNA - WM-115 [nTPM]":"1.0","Blood RNA - basophil [nTPM]":"1.5","Blood RNA - classical monocyte [nTPM]":"2.1","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"9.9","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"14.1","Blood RNA - memory B-cell [nTPM]":"11.1","Blood RNA - memory CD4 T-cell [nTPM]":"11.4","Blood RNA - memory CD8 T-cell [nTPM]":"17.6","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"15.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"6.7","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"4.2","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"37.4","Blood RNA - total PBMC [nTPM]":"3.6","Brain RNA - amygdala [nTPM]":"7.4","Brain RNA - basal ganglia [nTPM]":"8.3","Brain RNA - cerebellum [nTPM]":"5.9","Brain RNA - cerebral cortex [nTPM]":"8.5","Brain RNA - hippocampal formation [nTPM]":"6.7","Brain RNA - hypothalamus [nTPM]":"6.4","Brain RNA - medulla oblongata [nTPM]":"7.4","Brain RNA - midbrain [nTPM]":"5.8","Brain RNA - pons [nTPM]":"7.2","Brain RNA - spinal cord [nTPM]":"6.2","Brain RNA - thalamus [nTPM]":"8.0","Brain RNA - white matter [nTPM]":"9.2","Single Cell Type RNA - Adipocytes [nTPM]":"1.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"11.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"170.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"145.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.9","Single Cell Type RNA - dendritic cells [nTPM]":"6.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"29.7","Single Cell Type RNA - Early spermatids [nTPM]":"227.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"36.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.7","Single Cell Type RNA - Endothelial cells [nTPM]":"2.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"70.9","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"43.8","Single Cell Type RNA - Fibroblasts [nTPM]":"7.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.2","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"4.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.3","Single Cell Type RNA - Ionocytes [nTPM]":"122.1","Single Cell Type RNA - Kupffer cells [nTPM]":"10.5","Single Cell Type RNA - Langerhans cells [nTPM]":"4.2","Single Cell Type RNA - Late spermatids [nTPM]":"447.9","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"2.9","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"16.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.9","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"417.7","Single Cell Type RNA - Paneth cells [nTPM]":"12.1","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"38.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"35.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"32.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"221.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.8","Single Cell Type RNA - Spermatocytes [nTPM]":"7.2","Single Cell Type RNA - Spermatogonia [nTPM]":"6.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.2","Single Cell Type RNA - T-cells [nTPM]":"12.7","Single Cell Type RNA - Theca cells [nTPM]":"11.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.8","Single Cell Type RNA - Urothelial cells [nTPM]":"54.4"},{"Gene":"CDKN2B","Gene synonym":["CDK4I","INK4B","MTS2","P15","p15INK4b","TP15"],"Ensembl":"ENSG00000147883","Gene description":"Cyclin dependent kinase inhibitor 2B","Uniprot":["P42772"],"Chromosome":"9","Position":"22002903-22009305","Protein class":["Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle"],"Molecular function":null,"Disease involvement":["Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"36.2","intestine":"30.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"240.7","Pancreatic endocrine cells":"164.5","Proximal enterocytes":"139.0","Squamous epithelial cells":"142.0","Urothelial cells":"241.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"classical monocyte":"3.3","intermediate monocyte":"3.3","non-classical monocyte":"9.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"17","RNA blood lineage specific nTPM":{"monocytes":"9.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC TERT1":"38.1","HaCaT":"35.0","HeLa":"33.9","hTERT-RPE1":"60.1","SiHa":"48.0","SK-MEL-30":"35.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000349","HPA052838","HPA063327"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB000349":null,"HPA052838":null,"HPA063327":"AB_2684987"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.47e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.49e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.03e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Tissue RNA - adipose tissue [nTPM]":"18.7","Tissue RNA - adrenal gland [nTPM]":"1.9","Tissue RNA - amygdala [nTPM]":"2.0","Tissue RNA - appendix [nTPM]":"2.9","Tissue RNA - basal ganglia [nTPM]":"1.8","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"8.6","Tissue RNA - cerebellum [nTPM]":"1.1","Tissue RNA - cerebral cortex [nTPM]":"1.9","Tissue RNA - cervix [nTPM]":"9.6","Tissue RNA - choroid plexus [nTPM]":"9.1","Tissue RNA - colon [nTPM]":"22.4","Tissue RNA - duodenum [nTPM]":"21.7","Tissue RNA - endometrium 1 [nTPM]":"3.8","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"36.2","Tissue RNA - fallopian tube [nTPM]":"1.7","Tissue RNA - gallbladder [nTPM]":"2.4","Tissue RNA - heart muscle [nTPM]":"1.0","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"2.2","Tissue RNA - kidney [nTPM]":"1.2","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"12.6","Tissue RNA - lymph node [nTPM]":"1.1","Tissue RNA - medulla oblongata [nTPM]":"2.7","Tissue RNA - midbrain [nTPM]":"1.5","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"1.2","Tissue RNA - parathyroid gland [nTPM]":"3.3","Tissue RNA - pituitary gland [nTPM]":"3.5","Tissue RNA - placenta [nTPM]":"2.3","Tissue RNA - pons [nTPM]":"2.3","Tissue RNA - prostate [nTPM]":"3.6","Tissue RNA - rectum [nTPM]":"19.7","Tissue RNA - retina [nTPM]":"2.8","Tissue RNA - salivary gland [nTPM]":"6.7","Tissue RNA - seminal vesicle [nTPM]":"4.7","Tissue RNA - skeletal muscle [nTPM]":"7.2","Tissue RNA - skin 1 [nTPM]":"12.9","Tissue RNA - small intestine [nTPM]":"30.9","Tissue RNA - smooth muscle [nTPM]":"2.1","Tissue RNA - spinal cord [nTPM]":"1.7","Tissue RNA - spleen [nTPM]":"4.6","Tissue RNA - stomach 1 [nTPM]":"6.0","Tissue RNA - testis [nTPM]":"5.3","Tissue RNA - thalamus [nTPM]":"2.4","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"1.1","Tissue RNA - tongue [nTPM]":"1.1","Tissue RNA - tonsil [nTPM]":"8.1","Tissue RNA - urinary bladder [nTPM]":"7.9","Tissue RNA - vagina [nTPM]":"20.2","Tissue RNA - white matter [nTPM]":"2.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"2.1","Cell RNA - ASC diff [nTPM]":"28.2","Cell RNA - ASC TERT1 [nTPM]":"38.1","Cell RNA - BEWO [nTPM]":"0.7","Cell RNA - BJ [nTPM]":"1.8","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.6","Cell RNA - CACO-2 [nTPM]":"3.6","Cell RNA - CAPAN-2 [nTPM]":"10.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"3.4","Cell RNA - fHDF\/TERT166 [nTPM]":"2.3","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"35.0","Cell RNA - HAP1 [nTPM]":"0.8","Cell RNA - HBEC3-KT [nTPM]":"6.9","Cell RNA - HBF TERT88 [nTPM]":"5.5","Cell RNA - HDLM-2 [nTPM]":"2.6","Cell RNA - HEK 293 [nTPM]":"9.7","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"33.9","Cell RNA - Hep G2 [nTPM]":"1.5","Cell RNA - HHSteC [nTPM]":"14.4","Cell RNA - HL-60 [nTPM]":"1.1","Cell RNA - HMC-1 [nTPM]":"6.1","Cell RNA - HSkMC [nTPM]":"8.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.5","Cell RNA - hTERT-HME1 [nTPM]":"25.8","Cell RNA - hTERT-RPE1 [nTPM]":"60.1","Cell RNA - HUVEC TERT2 [nTPM]":"4.4","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"17.1","Cell RNA - LHCN-M2 [nTPM]":"7.3","Cell RNA - MCF7 [nTPM]":"2.8","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"1.7","Cell RNA - OE19 [nTPM]":"1.7","Cell RNA - PC-3 [nTPM]":"19.5","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"2.4","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"10.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"5.4","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"48.0","Cell RNA - SK-BR-3 [nTPM]":"11.5","Cell RNA - SK-MEL-30 [nTPM]":"35.7","Cell RNA - SuSa [nTPM]":"25.8","Cell RNA - T-47d [nTPM]":"3.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"14.8","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"13.5","Cell RNA - U-266\/84 [nTPM]":"8.4","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"1.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"3.3","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"3.3","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"9.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"2.0","Brain RNA - basal ganglia [nTPM]":"1.8","Brain RNA - cerebellum [nTPM]":"1.1","Brain RNA - cerebral cortex [nTPM]":"1.9","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"2.2","Brain RNA - medulla oblongata [nTPM]":"2.7","Brain RNA - midbrain [nTPM]":"1.5","Brain RNA - pons [nTPM]":"2.3","Brain RNA - spinal cord [nTPM]":"1.7","Brain RNA - thalamus [nTPM]":"2.4","Brain RNA - white matter [nTPM]":"2.4","Single Cell Type RNA - Adipocytes [nTPM]":"3.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"67.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"2.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"40.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"3.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"37.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - dendritic cells [nTPM]":"3.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"240.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"57.7","Single Cell Type RNA - Early spermatids [nTPM]":"11.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"31.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.5","Single Cell Type RNA - Endothelial cells [nTPM]":"4.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.7","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"38.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"11.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"30.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"37.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.6","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"17.6","Single Cell Type RNA - Langerhans cells [nTPM]":"3.8","Single Cell Type RNA - Late spermatids [nTPM]":"2.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"5.6","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"3.2","Single Cell Type RNA - Muller glia cells [nTPM]":"4.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"164.5","Single Cell Type RNA - Paneth cells [nTPM]":"75.6","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"2.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"65.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"139.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.9","Single Cell Type RNA - Spermatocytes [nTPM]":"13.8","Single Cell Type RNA - Spermatogonia [nTPM]":"3.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"142.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.1","Single Cell Type RNA - T-cells [nTPM]":"2.9","Single Cell Type RNA - Theca cells [nTPM]":"1.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.3","Single Cell Type RNA - Urothelial cells [nTPM]":"241.6"},{"Gene":"FAS","Gene synonym":["APO-1","APT1","CD95","FAS1","TNFRSF6"],"Ensembl":"ENSG00000026103","Gene description":"Fas cell surface death receptor","Uniprot":["P25445"],"Chromosome":"10","Position":"88990531-89017059","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","CD markers","Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Apoptosis"],"Molecular function":["Calmodulin-binding","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"109.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"114.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"114.7","T-cells":"96.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"83.4","Karpas-707":"109.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027444"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies","Plasma membrane","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":11900000,"Blood concentration - Conc. blood MS [pg\/L]":"420000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear bodies","Cytosol"],"Antibody RRID":{"HPA027444":"AB_10601378"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Tissue RNA - adipose tissue [nTPM]":"14.1","Tissue RNA - adrenal gland [nTPM]":"26.3","Tissue RNA - amygdala [nTPM]":"3.6","Tissue RNA - appendix [nTPM]":"17.0","Tissue RNA - basal ganglia [nTPM]":"3.6","Tissue RNA - bone marrow [nTPM]":"20.8","Tissue RNA - breast [nTPM]":"10.9","Tissue RNA - cerebellum [nTPM]":"2.9","Tissue RNA - cerebral cortex [nTPM]":"4.7","Tissue RNA - cervix [nTPM]":"12.7","Tissue RNA - choroid plexus [nTPM]":"2.8","Tissue RNA - colon [nTPM]":"16.4","Tissue RNA - duodenum [nTPM]":"7.0","Tissue RNA - endometrium 1 [nTPM]":"12.8","Tissue RNA - epididymis [nTPM]":"10.3","Tissue RNA - esophagus [nTPM]":"10.8","Tissue RNA - fallopian tube [nTPM]":"14.8","Tissue RNA - gallbladder [nTPM]":"15.7","Tissue RNA - heart muscle [nTPM]":"7.5","Tissue RNA - hippocampal formation [nTPM]":"3.6","Tissue RNA - hypothalamus [nTPM]":"3.7","Tissue RNA - kidney [nTPM]":"7.2","Tissue RNA - liver [nTPM]":"23.3","Tissue RNA - lung [nTPM]":"21.7","Tissue RNA - lymph node [nTPM]":"18.9","Tissue RNA - medulla oblongata [nTPM]":"4.6","Tissue RNA - midbrain [nTPM]":"3.1","Tissue RNA - ovary [nTPM]":"20.1","Tissue RNA - pancreas [nTPM]":"3.7","Tissue RNA - parathyroid gland [nTPM]":"2.7","Tissue RNA - pituitary gland [nTPM]":"3.7","Tissue RNA - placenta [nTPM]":"10.4","Tissue RNA - pons [nTPM]":"4.0","Tissue RNA - prostate [nTPM]":"8.9","Tissue RNA - rectum [nTPM]":"23.3","Tissue RNA - retina [nTPM]":"3.3","Tissue RNA - salivary gland [nTPM]":"6.5","Tissue RNA - seminal vesicle [nTPM]":"9.3","Tissue RNA - skeletal muscle [nTPM]":"2.3","Tissue RNA - skin 1 [nTPM]":"9.4","Tissue RNA - small intestine [nTPM]":"9.2","Tissue RNA - smooth muscle [nTPM]":"15.0","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"11.2","Tissue RNA - stomach 1 [nTPM]":"4.4","Tissue RNA - testis [nTPM]":"2.6","Tissue RNA - thalamus [nTPM]":"3.9","Tissue RNA - thymus [nTPM]":"14.4","Tissue RNA - thyroid gland [nTPM]":"7.3","Tissue RNA - tongue [nTPM]":"2.6","Tissue RNA - tonsil [nTPM]":"15.6","Tissue RNA - urinary bladder [nTPM]":"12.9","Tissue RNA - vagina [nTPM]":"10.2","Tissue RNA - white matter [nTPM]":"4.3","Cell RNA - A-431 [nTPM]":"22.7","Cell RNA - A549 [nTPM]":"8.2","Cell RNA - AF22 [nTPM]":"5.4","Cell RNA - AN3-CA [nTPM]":"13.9","Cell RNA - ASC diff [nTPM]":"37.0","Cell RNA - ASC TERT1 [nTPM]":"51.3","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"51.8","Cell RNA - BJ hTERT+ [nTPM]":"50.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.1","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"23.4","Cell RNA - Daudi [nTPM]":"4.7","Cell RNA - EFO-21 [nTPM]":"19.0","Cell RNA - fHDF\/TERT166 [nTPM]":"52.1","Cell RNA - GAMG [nTPM]":"9.6","Cell RNA - HaCaT [nTPM]":"4.0","Cell RNA - HAP1 [nTPM]":"1.0","Cell RNA - HBEC3-KT [nTPM]":"44.8","Cell RNA - HBF TERT88 [nTPM]":"3.2","Cell RNA - HDLM-2 [nTPM]":"83.4","Cell RNA - HEK 293 [nTPM]":"8.7","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"5.2","Cell RNA - Hep G2 [nTPM]":"14.7","Cell RNA - HHSteC [nTPM]":"31.6","Cell RNA - HL-60 [nTPM]":"3.4","Cell RNA - HMC-1 [nTPM]":"1.6","Cell RNA - HSkMC [nTPM]":"69.2","Cell RNA - hTCEpi [nTPM]":"38.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"31.4","Cell RNA - hTERT-HME1 [nTPM]":"66.0","Cell RNA - hTERT-RPE1 [nTPM]":"24.5","Cell RNA - HUVEC TERT2 [nTPM]":"4.7","Cell RNA - JURKAT [nTPM]":"17.8","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"109.0","Cell RNA - LHCN-M2 [nTPM]":"44.0","Cell RNA - MCF7 [nTPM]":"1.4","Cell RNA - MOLT-4 [nTPM]":"6.4","Cell RNA - NB-4 [nTPM]":"3.4","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"1.8","Cell RNA - REH [nTPM]":"1.4","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"5.0","Cell RNA - RPTEC TERT1 [nTPM]":"60.7","Cell RNA - RT4 [nTPM]":"7.3","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"7.7","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"7.0","Cell RNA - T-47d [nTPM]":"13.9","Cell RNA - THP-1 [nTPM]":"1.0","Cell RNA - TIME [nTPM]":"9.5","Cell RNA - U-138 MG [nTPM]":"15.8","Cell RNA - U-2 OS [nTPM]":"9.0","Cell RNA - U-2197 [nTPM]":"15.2","Cell RNA - U-251 MG [nTPM]":"12.3","Cell RNA - U-266\/70 [nTPM]":"45.3","Cell RNA - U-266\/84 [nTPM]":"5.3","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"11.8","Cell RNA - U-937 [nTPM]":"10.2","Cell RNA - WM-115 [nTPM]":"4.5","Blood RNA - basophil [nTPM]":"43.1","Blood RNA - classical monocyte [nTPM]":"9.4","Blood RNA - eosinophil [nTPM]":"30.9","Blood RNA - gdT-cell [nTPM]":"9.9","Blood RNA - intermediate monocyte [nTPM]":"12.3","Blood RNA - MAIT T-cell [nTPM]":"13.8","Blood RNA - memory B-cell [nTPM]":"7.5","Blood RNA - memory CD4 T-cell [nTPM]":"27.6","Blood RNA - memory CD8 T-cell [nTPM]":"19.6","Blood RNA - myeloid DC [nTPM]":"11.5","Blood RNA - naive B-cell [nTPM]":"4.0","Blood RNA - naive CD4 T-cell [nTPM]":"3.1","Blood RNA - naive CD8 T-cell [nTPM]":"10.0","Blood RNA - neutrophil [nTPM]":"114.7","Blood RNA - NK-cell [nTPM]":"3.1","Blood RNA - non-classical monocyte [nTPM]":"22.1","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"96.2","Blood RNA - total PBMC [nTPM]":"12.8","Brain RNA - amygdala [nTPM]":"3.6","Brain RNA - basal ganglia [nTPM]":"3.6","Brain RNA - cerebellum [nTPM]":"2.9","Brain RNA - cerebral cortex [nTPM]":"4.7","Brain RNA - hippocampal formation [nTPM]":"3.6","Brain RNA - hypothalamus [nTPM]":"3.7","Brain RNA - medulla oblongata [nTPM]":"4.6","Brain RNA - midbrain [nTPM]":"3.1","Brain RNA - pons [nTPM]":"4.0","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"3.9","Brain RNA - white matter [nTPM]":"4.3","Single Cell Type RNA - Adipocytes [nTPM]":"10.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"57.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.8","Single Cell Type RNA - Astrocytes [nTPM]":"40.1","Single Cell Type RNA - B-cells [nTPM]":"12.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"45.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"109.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"53.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"39.9","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"27.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"16.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.3","Single Cell Type RNA - Early spermatids [nTPM]":"11.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.3","Single Cell Type RNA - Endothelial cells [nTPM]":"8.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"9.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"35.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.5","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"4.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"19.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.5","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.4","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.0","Single Cell Type RNA - Langerhans cells [nTPM]":"31.7","Single Cell Type RNA - Late spermatids [nTPM]":"4.9","Single Cell Type RNA - Leydig cells [nTPM]":"19.0","Single Cell Type RNA - Macrophages [nTPM]":"17.7","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"20.9","Single Cell Type RNA - Muller glia cells [nTPM]":"14.5","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.5","Single Cell Type RNA - Paneth cells [nTPM]":"8.7","Single Cell Type RNA - Peritubular cells [nTPM]":"13.9","Single Cell Type RNA - Plasma cells [nTPM]":"32.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"46.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"26.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"26.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"29.1","Single Cell Type RNA - Spermatocytes [nTPM]":"11.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"43.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"48.4","Single Cell Type RNA - Theca cells [nTPM]":"11.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.4","Single Cell Type RNA - Urothelial cells [nTPM]":"30.0"},{"Gene":"HRAS","Gene synonym":["HRAS1"],"Ensembl":"ENSG00000174775","Gene description":"HRas proto-oncogene, GTPase","Uniprot":["P01112"],"Chromosome":"11","Position":"532242-537287","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Suprabasal keratinocytes":"145.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"4.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002015","HPA049830","HPA070222"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB002015":null,"HPA049830":"AB_2680903","HPA070222":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.32e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Tissue RNA - adipose tissue [nTPM]":"28.1","Tissue RNA - adrenal gland [nTPM]":"24.6","Tissue RNA - amygdala [nTPM]":"64.6","Tissue RNA - appendix [nTPM]":"3.5","Tissue RNA - basal ganglia [nTPM]":"67.2","Tissue RNA - bone marrow [nTPM]":"2.9","Tissue RNA - breast [nTPM]":"27.0","Tissue RNA - cerebellum [nTPM]":"62.1","Tissue RNA - cerebral cortex [nTPM]":"86.8","Tissue RNA - cervix [nTPM]":"30.4","Tissue RNA - choroid plexus [nTPM]":"58.3","Tissue RNA - colon [nTPM]":"34.3","Tissue RNA - duodenum [nTPM]":"2.8","Tissue RNA - endometrium 1 [nTPM]":"23.6","Tissue RNA - epididymis [nTPM]":"12.5","Tissue RNA - esophagus [nTPM]":"80.1","Tissue RNA - fallopian tube [nTPM]":"18.9","Tissue RNA - gallbladder [nTPM]":"3.6","Tissue RNA - heart muscle [nTPM]":"56.8","Tissue RNA - hippocampal formation [nTPM]":"64.4","Tissue RNA - hypothalamus [nTPM]":"64.6","Tissue RNA - kidney [nTPM]":"33.8","Tissue RNA - liver [nTPM]":"21.8","Tissue RNA - lung [nTPM]":"27.1","Tissue RNA - lymph node [nTPM]":"4.3","Tissue RNA - medulla oblongata [nTPM]":"65.6","Tissue RNA - midbrain [nTPM]":"65.3","Tissue RNA - ovary [nTPM]":"20.0","Tissue RNA - pancreas [nTPM]":"20.5","Tissue RNA - parathyroid gland [nTPM]":"13.1","Tissue RNA - pituitary gland [nTPM]":"38.2","Tissue RNA - placenta [nTPM]":"9.0","Tissue RNA - pons [nTPM]":"66.9","Tissue RNA - prostate [nTPM]":"38.3","Tissue RNA - rectum [nTPM]":"6.9","Tissue RNA - retina [nTPM]":"10.2","Tissue RNA - salivary gland [nTPM]":"27.3","Tissue RNA - seminal vesicle [nTPM]":"12.3","Tissue RNA - skeletal muscle [nTPM]":"59.0","Tissue RNA - skin 1 [nTPM]":"69.9","Tissue RNA - small intestine [nTPM]":"19.5","Tissue RNA - smooth muscle [nTPM]":"8.9","Tissue RNA - spinal cord [nTPM]":"64.2","Tissue RNA - spleen [nTPM]":"20.6","Tissue RNA - stomach 1 [nTPM]":"24.2","Tissue RNA - testis [nTPM]":"16.5","Tissue RNA - thalamus [nTPM]":"64.8","Tissue RNA - thymus [nTPM]":"9.2","Tissue RNA - thyroid gland [nTPM]":"20.5","Tissue RNA - tongue [nTPM]":"25.2","Tissue RNA - tonsil [nTPM]":"10.2","Tissue RNA - urinary bladder [nTPM]":"34.5","Tissue RNA - vagina [nTPM]":"44.2","Tissue RNA - white matter [nTPM]":"65.4","Cell RNA - A-431 [nTPM]":"59.0","Cell RNA - A549 [nTPM]":"105.6","Cell RNA - AF22 [nTPM]":"44.2","Cell RNA - AN3-CA [nTPM]":"25.6","Cell RNA - ASC diff [nTPM]":"22.2","Cell RNA - ASC TERT1 [nTPM]":"17.5","Cell RNA - BEWO [nTPM]":"39.6","Cell RNA - BJ [nTPM]":"49.9","Cell RNA - BJ hTERT+ [nTPM]":"25.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"64.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"29.5","Cell RNA - CACO-2 [nTPM]":"62.4","Cell RNA - CAPAN-2 [nTPM]":"29.7","Cell RNA - Daudi [nTPM]":"20.4","Cell RNA - EFO-21 [nTPM]":"10.9","Cell RNA - fHDF\/TERT166 [nTPM]":"63.2","Cell RNA - GAMG [nTPM]":"60.7","Cell RNA - HaCaT [nTPM]":"43.7","Cell RNA - HAP1 [nTPM]":"46.0","Cell RNA - HBEC3-KT [nTPM]":"114.1","Cell RNA - HBF TERT88 [nTPM]":"19.3","Cell RNA - HDLM-2 [nTPM]":"19.5","Cell RNA - HEK 293 [nTPM]":"108.4","Cell RNA - HEL [nTPM]":"6.6","Cell RNA - HeLa [nTPM]":"43.7","Cell RNA - Hep G2 [nTPM]":"56.1","Cell RNA - HHSteC [nTPM]":"38.5","Cell RNA - HL-60 [nTPM]":"13.9","Cell RNA - HMC-1 [nTPM]":"12.0","Cell RNA - HSkMC [nTPM]":"28.3","Cell RNA - hTCEpi [nTPM]":"118.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"42.0","Cell RNA - hTERT-HME1 [nTPM]":"51.5","Cell RNA - hTERT-RPE1 [nTPM]":"19.6","Cell RNA - HUVEC TERT2 [nTPM]":"31.5","Cell RNA - JURKAT [nTPM]":"34.3","Cell RNA - K-562 [nTPM]":"29.7","Cell RNA - Karpas-707 [nTPM]":"32.3","Cell RNA - LHCN-M2 [nTPM]":"40.9","Cell RNA - MCF7 [nTPM]":"110.6","Cell RNA - MOLT-4 [nTPM]":"34.0","Cell RNA - NB-4 [nTPM]":"50.5","Cell RNA - NTERA-2 [nTPM]":"26.5","Cell RNA - OE19 [nTPM]":"39.9","Cell RNA - PC-3 [nTPM]":"94.5","Cell RNA - REH [nTPM]":"31.6","Cell RNA - RH-30 [nTPM]":"40.7","Cell RNA - RPMI-8226 [nTPM]":"18.2","Cell RNA - RPTEC TERT1 [nTPM]":"47.0","Cell RNA - RT4 [nTPM]":"33.2","Cell RNA - SCLC-21H [nTPM]":"87.6","Cell RNA - SH-SY5Y [nTPM]":"43.7","Cell RNA - SiHa [nTPM]":"25.5","Cell RNA - SK-BR-3 [nTPM]":"55.4","Cell RNA - SK-MEL-30 [nTPM]":"17.9","Cell RNA - SuSa [nTPM]":"31.5","Cell RNA - T-47d [nTPM]":"43.3","Cell RNA - THP-1 [nTPM]":"14.8","Cell RNA - TIME [nTPM]":"35.4","Cell RNA - U-138 MG [nTPM]":"47.3","Cell RNA - U-2 OS [nTPM]":"44.7","Cell RNA - U-2197 [nTPM]":"16.4","Cell RNA - U-251 MG [nTPM]":"39.7","Cell RNA - U-266\/70 [nTPM]":"20.3","Cell RNA - U-266\/84 [nTPM]":"17.7","Cell RNA - U-698 [nTPM]":"15.4","Cell RNA - U-87 MG [nTPM]":"39.1","Cell RNA - U-937 [nTPM]":"17.0","Cell RNA - WM-115 [nTPM]":"38.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"2.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.9","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"4.0","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"1.5","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"64.6","Brain RNA - basal ganglia [nTPM]":"67.2","Brain RNA - cerebellum [nTPM]":"62.1","Brain RNA - cerebral cortex [nTPM]":"86.8","Brain RNA - hippocampal formation [nTPM]":"64.4","Brain RNA - hypothalamus [nTPM]":"64.6","Brain RNA - medulla oblongata [nTPM]":"65.6","Brain RNA - midbrain [nTPM]":"65.3","Brain RNA - pons [nTPM]":"66.9","Brain RNA - spinal cord [nTPM]":"64.2","Brain RNA - thalamus [nTPM]":"64.8","Brain RNA - white matter [nTPM]":"65.4","Single Cell Type RNA - Adipocytes [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.7","Single Cell Type RNA - Astrocytes [nTPM]":"9.1","Single Cell Type RNA - B-cells [nTPM]":"18.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"131.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"101.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"25.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"82.0","Single Cell Type RNA - Bipolar cells [nTPM]":"46.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"38.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"75.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"11.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"78.8","Single Cell Type RNA - dendritic cells [nTPM]":"21.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"72.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"74.3","Single Cell Type RNA - Ductal cells [nTPM]":"35.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"36.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"28.6","Single Cell Type RNA - Endothelial cells [nTPM]":"32.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"29.3","Single Cell Type RNA - Erythroid cells [nTPM]":"11.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"37.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"63.4","Single Cell Type RNA - Fibroblasts [nTPM]":"25.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"34.1","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"26.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.9","Single Cell Type RNA - Hepatocytes [nTPM]":"17.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"39.9","Single Cell Type RNA - Horizontal cells [nTPM]":"48.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.5","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"11.7","Single Cell Type RNA - Langerhans cells [nTPM]":"38.4","Single Cell Type RNA - Late spermatids [nTPM]":"7.9","Single Cell Type RNA - Leydig cells [nTPM]":"17.1","Single Cell Type RNA - Macrophages [nTPM]":"21.3","Single Cell Type RNA - Melanocytes [nTPM]":"64.0","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"12.8","Single Cell Type RNA - Muller glia cells [nTPM]":"50.8","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"48.2","Single Cell Type RNA - Paneth cells [nTPM]":"30.9","Single Cell Type RNA - Peritubular cells [nTPM]":"23.0","Single Cell Type RNA - Plasma cells [nTPM]":"26.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"61.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"30.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"54.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"37.6","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"40.3","Single Cell Type RNA - Spermatocytes [nTPM]":"5.4","Single Cell Type RNA - Spermatogonia [nTPM]":"21.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"118.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"145.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"78.1","Single Cell Type RNA - T-cells [nTPM]":"22.0","Single Cell Type RNA - Theca cells [nTPM]":"18.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.2","Single Cell Type RNA - Urothelial cells [nTPM]":"106.4"},{"Gene":"JUNB","Gene synonym":[],"Ensembl":"ENSG00000171223","Gene description":"JunB proto-oncogene, AP-1 transcription factor subunit","Uniprot":["P17275"],"Chromosome":"19","Position":"12791486-12793315","Protein class":["Human disease related genes","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"679.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"679.4","monocytes":"182.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"629.0","U-266\/70":"256.4","U-266\/84":"411.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004464","HPA019149"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB004464":"AB_2130023","HPA019149":"AB_1852053"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.65e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.05e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"722.8","Tissue RNA - adrenal gland [nTPM]":"259.5","Tissue RNA - amygdala [nTPM]":"22.9","Tissue RNA - appendix [nTPM]":"110.3","Tissue RNA - basal ganglia [nTPM]":"28.0","Tissue RNA - bone marrow [nTPM]":"455.2","Tissue RNA - breast [nTPM]":"248.5","Tissue RNA - cerebellum [nTPM]":"90.1","Tissue RNA - cerebral cortex [nTPM]":"65.2","Tissue RNA - cervix [nTPM]":"283.3","Tissue RNA - choroid plexus [nTPM]":"30.4","Tissue RNA - colon [nTPM]":"287.0","Tissue RNA - duodenum [nTPM]":"52.8","Tissue RNA - endometrium 1 [nTPM]":"130.1","Tissue RNA - epididymis [nTPM]":"2.2","Tissue RNA - esophagus [nTPM]":"449.1","Tissue RNA - fallopian tube [nTPM]":"874.8","Tissue RNA - gallbladder [nTPM]":"92.6","Tissue RNA - heart muscle [nTPM]":"383.5","Tissue RNA - hippocampal formation [nTPM]":"28.3","Tissue RNA - hypothalamus [nTPM]":"68.8","Tissue RNA - kidney [nTPM]":"184.2","Tissue RNA - liver [nTPM]":"279.0","Tissue RNA - lung [nTPM]":"399.2","Tissue RNA - lymph node [nTPM]":"65.0","Tissue RNA - medulla oblongata [nTPM]":"83.5","Tissue RNA - midbrain [nTPM]":"29.8","Tissue RNA - ovary [nTPM]":"649.5","Tissue RNA - pancreas [nTPM]":"150.0","Tissue RNA - parathyroid gland [nTPM]":"20.8","Tissue RNA - pituitary gland [nTPM]":"351.9","Tissue RNA - placenta [nTPM]":"39.4","Tissue RNA - pons [nTPM]":"33.6","Tissue RNA - prostate [nTPM]":"195.0","Tissue RNA - rectum [nTPM]":"22.0","Tissue RNA - retina [nTPM]":"32.0","Tissue RNA - salivary gland [nTPM]":"131.6","Tissue RNA - seminal vesicle [nTPM]":"56.1","Tissue RNA - skeletal muscle [nTPM]":"144.6","Tissue RNA - skin 1 [nTPM]":"605.9","Tissue RNA - small intestine [nTPM]":"145.0","Tissue RNA - smooth muscle [nTPM]":"58.1","Tissue RNA - spinal cord [nTPM]":"51.5","Tissue RNA - spleen [nTPM]":"153.3","Tissue RNA - stomach 1 [nTPM]":"309.8","Tissue RNA - testis [nTPM]":"30.0","Tissue RNA - thalamus [nTPM]":"31.3","Tissue RNA - thymus [nTPM]":"78.8","Tissue RNA - thyroid gland [nTPM]":"198.7","Tissue RNA - tongue [nTPM]":"73.3","Tissue RNA - tonsil [nTPM]":"12.9","Tissue RNA - urinary bladder [nTPM]":"333.0","Tissue RNA - vagina [nTPM]":"330.6","Tissue RNA - white matter [nTPM]":"34.8","Cell RNA - A-431 [nTPM]":"52.9","Cell RNA - A549 [nTPM]":"10.4","Cell RNA - AF22 [nTPM]":"2.8","Cell RNA - AN3-CA [nTPM]":"6.4","Cell RNA - ASC diff [nTPM]":"11.3","Cell RNA - ASC TERT1 [nTPM]":"27.4","Cell RNA - BEWO [nTPM]":"10.2","Cell RNA - BJ [nTPM]":"22.8","Cell RNA - BJ hTERT+ [nTPM]":"19.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.0","Cell RNA - CACO-2 [nTPM]":"6.8","Cell RNA - CAPAN-2 [nTPM]":"30.4","Cell RNA - Daudi [nTPM]":"18.2","Cell RNA - EFO-21 [nTPM]":"77.4","Cell RNA - fHDF\/TERT166 [nTPM]":"8.4","Cell RNA - GAMG [nTPM]":"33.5","Cell RNA - HaCaT [nTPM]":"98.5","Cell RNA - HAP1 [nTPM]":"2.5","Cell RNA - HBEC3-KT [nTPM]":"34.3","Cell RNA - HBF TERT88 [nTPM]":"1.2","Cell RNA - HDLM-2 [nTPM]":"629.0","Cell RNA - HEK 293 [nTPM]":"9.9","Cell RNA - HEL [nTPM]":"18.0","Cell RNA - HeLa [nTPM]":"42.2","Cell RNA - Hep G2 [nTPM]":"9.0","Cell RNA - HHSteC [nTPM]":"15.1","Cell RNA - HL-60 [nTPM]":"24.3","Cell RNA - HMC-1 [nTPM]":"80.5","Cell RNA - HSkMC [nTPM]":"34.9","Cell RNA - hTCEpi [nTPM]":"97.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.0","Cell RNA - hTERT-HME1 [nTPM]":"7.5","Cell RNA - hTERT-RPE1 [nTPM]":"22.0","Cell RNA - HUVEC TERT2 [nTPM]":"5.3","Cell RNA - JURKAT [nTPM]":"12.9","Cell RNA - K-562 [nTPM]":"48.1","Cell RNA - Karpas-707 [nTPM]":"32.6","Cell RNA - LHCN-M2 [nTPM]":"3.6","Cell RNA - MCF7 [nTPM]":"158.8","Cell RNA - MOLT-4 [nTPM]":"16.8","Cell RNA - NB-4 [nTPM]":"147.5","Cell RNA - NTERA-2 [nTPM]":"1.7","Cell RNA - OE19 [nTPM]":"36.1","Cell RNA - PC-3 [nTPM]":"40.0","Cell RNA - REH [nTPM]":"22.4","Cell RNA - RH-30 [nTPM]":"7.7","Cell RNA - RPMI-8226 [nTPM]":"38.8","Cell RNA - RPTEC TERT1 [nTPM]":"7.5","Cell RNA - RT4 [nTPM]":"65.5","Cell RNA - SCLC-21H [nTPM]":"23.7","Cell RNA - SH-SY5Y [nTPM]":"36.0","Cell RNA - SiHa [nTPM]":"98.4","Cell RNA - SK-BR-3 [nTPM]":"59.5","Cell RNA - SK-MEL-30 [nTPM]":"30.5","Cell RNA - SuSa [nTPM]":"1.7","Cell RNA - T-47d [nTPM]":"10.5","Cell RNA - THP-1 [nTPM]":"27.0","Cell RNA - TIME [nTPM]":"17.6","Cell RNA - U-138 MG [nTPM]":"32.2","Cell RNA - U-2 OS [nTPM]":"18.7","Cell RNA - U-2197 [nTPM]":"64.3","Cell RNA - U-251 MG [nTPM]":"28.9","Cell RNA - U-266\/70 [nTPM]":"256.4","Cell RNA - U-266\/84 [nTPM]":"411.4","Cell RNA - U-698 [nTPM]":"17.1","Cell RNA - U-87 MG [nTPM]":"37.7","Cell RNA - U-937 [nTPM]":"62.7","Cell RNA - WM-115 [nTPM]":"8.9","Blood RNA - basophil [nTPM]":"29.1","Blood RNA - classical monocyte [nTPM]":"132.2","Blood RNA - eosinophil [nTPM]":"132.2","Blood RNA - gdT-cell [nTPM]":"33.4","Blood RNA - intermediate monocyte [nTPM]":"182.7","Blood RNA - MAIT T-cell [nTPM]":"33.4","Blood RNA - memory B-cell [nTPM]":"30.6","Blood RNA - memory CD4 T-cell [nTPM]":"36.8","Blood RNA - memory CD8 T-cell [nTPM]":"42.0","Blood RNA - myeloid DC [nTPM]":"87.1","Blood RNA - naive B-cell [nTPM]":"25.4","Blood RNA - naive CD4 T-cell [nTPM]":"25.5","Blood RNA - naive CD8 T-cell [nTPM]":"28.5","Blood RNA - neutrophil [nTPM]":"679.4","Blood RNA - NK-cell [nTPM]":"18.6","Blood RNA - non-classical monocyte [nTPM]":"177.2","Blood RNA - plasmacytoid DC [nTPM]":"7.9","Blood RNA - T-reg [nTPM]":"38.7","Blood RNA - total PBMC [nTPM]":"124.1","Brain RNA - amygdala [nTPM]":"22.9","Brain RNA - basal ganglia [nTPM]":"28.0","Brain RNA - cerebellum [nTPM]":"90.1","Brain RNA - cerebral cortex [nTPM]":"65.2","Brain RNA - hippocampal formation [nTPM]":"28.3","Brain RNA - hypothalamus [nTPM]":"68.8","Brain RNA - medulla oblongata [nTPM]":"83.5","Brain RNA - midbrain [nTPM]":"29.8","Brain RNA - pons [nTPM]":"33.6","Brain RNA - spinal cord [nTPM]":"51.5","Brain RNA - thalamus [nTPM]":"31.3","Brain RNA - white matter [nTPM]":"34.8","Single Cell Type RNA - Adipocytes [nTPM]":"3158.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"115.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"423.2","Single Cell Type RNA - Astrocytes [nTPM]":"130.2","Single Cell Type RNA - B-cells [nTPM]":"1751.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1463.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1778.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2367.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1985.1","Single Cell Type RNA - Bipolar cells [nTPM]":"81.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1296.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1693.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"374.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"474.7","Single Cell Type RNA - Club cells [nTPM]":"707.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"154.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"129.7","Single Cell Type RNA - dendritic cells [nTPM]":"1766.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"819.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"49.0","Single Cell Type RNA - Ductal cells [nTPM]":"833.3","Single Cell Type RNA - Early spermatids [nTPM]":"9.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"468.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1091.4","Single Cell Type RNA - Endothelial cells [nTPM]":"1469.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1502.1","Single Cell Type RNA - Erythroid cells [nTPM]":"244.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"546.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"224.7","Single Cell Type RNA - Fibroblasts [nTPM]":"2182.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1060.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"627.8","Single Cell Type RNA - granulocytes [nTPM]":"510.5","Single Cell Type RNA - Granulosa cells [nTPM]":"310.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"852.4","Single Cell Type RNA - Hepatocytes [nTPM]":"84.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"1178.4","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1029.3","Single Cell Type RNA - Ionocytes [nTPM]":"740.6","Single Cell Type RNA - Kupffer cells [nTPM]":"674.1","Single Cell Type RNA - Langerhans cells [nTPM]":"2747.6","Single Cell Type RNA - Late spermatids [nTPM]":"27.9","Single Cell Type RNA - Leydig cells [nTPM]":"815.2","Single Cell Type RNA - Macrophages [nTPM]":"1583.3","Single Cell Type RNA - Melanocytes [nTPM]":"894.6","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"379.3","Single Cell Type RNA - Muller glia cells [nTPM]":"634.6","Single Cell Type RNA - NK-cells [nTPM]":"115.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1026.7","Single Cell Type RNA - Paneth cells [nTPM]":"875.3","Single Cell Type RNA - Peritubular cells [nTPM]":"263.3","Single Cell Type RNA - Plasma cells [nTPM]":"842.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1036.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"701.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"84.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"337.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"168.8","Single Cell Type RNA - Sertoli cells [nTPM]":"1163.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2566.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2624.1","Single Cell Type RNA - Spermatocytes [nTPM]":"9.4","Single Cell Type RNA - Spermatogonia [nTPM]":"10.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1164.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1804.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"440.3","Single Cell Type RNA - T-cells [nTPM]":"2362.6","Single Cell Type RNA - Theca cells [nTPM]":"417.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"687.7","Single Cell Type RNA - Urothelial cells [nTPM]":"472.6"},{"Gene":"KRAS","Gene synonym":["KRAS1","KRAS2"],"Ensembl":"ENSG00000133703","Gene description":"KRAS proto-oncogene, GTPase","Uniprot":["P01116"],"Chromosome":"12","Position":"25205246-25250936","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","Cardiomyopathy","Deafness","Disease variant","Ectodermal dysplasia","Mental retardation","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049830"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3300000","Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049830":"AB_2680903"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.59e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.75e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.97e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.8","Tissue RNA - adrenal gland [nTPM]":"9.1","Tissue RNA - amygdala [nTPM]":"11.0","Tissue RNA - appendix [nTPM]":"16.2","Tissue RNA - basal ganglia [nTPM]":"12.2","Tissue RNA - bone marrow [nTPM]":"27.8","Tissue RNA - breast [nTPM]":"10.0","Tissue RNA - cerebellum [nTPM]":"11.7","Tissue RNA - cerebral cortex [nTPM]":"12.3","Tissue RNA - cervix [nTPM]":"9.5","Tissue RNA - choroid plexus [nTPM]":"4.6","Tissue RNA - colon [nTPM]":"22.0","Tissue RNA - duodenum [nTPM]":"14.0","Tissue RNA - endometrium 1 [nTPM]":"11.0","Tissue RNA - epididymis [nTPM]":"6.8","Tissue RNA - esophagus [nTPM]":"19.3","Tissue RNA - fallopian tube [nTPM]":"7.4","Tissue RNA - gallbladder [nTPM]":"13.1","Tissue RNA - heart muscle [nTPM]":"8.6","Tissue RNA - hippocampal formation [nTPM]":"12.5","Tissue RNA - hypothalamus [nTPM]":"12.0","Tissue RNA - kidney [nTPM]":"11.7","Tissue RNA - liver [nTPM]":"15.3","Tissue RNA - lung [nTPM]":"13.2","Tissue RNA - lymph node [nTPM]":"17.9","Tissue RNA - medulla oblongata [nTPM]":"8.5","Tissue RNA - midbrain [nTPM]":"9.7","Tissue RNA - ovary [nTPM]":"8.0","Tissue RNA - pancreas [nTPM]":"12.6","Tissue RNA - parathyroid gland [nTPM]":"11.1","Tissue RNA - pituitary gland [nTPM]":"5.7","Tissue RNA - placenta [nTPM]":"17.0","Tissue RNA - pons [nTPM]":"8.7","Tissue RNA - prostate [nTPM]":"11.8","Tissue RNA - rectum [nTPM]":"23.0","Tissue RNA - retina [nTPM]":"22.7","Tissue RNA - salivary gland [nTPM]":"11.9","Tissue RNA - seminal vesicle [nTPM]":"8.3","Tissue RNA - skeletal muscle [nTPM]":"7.6","Tissue RNA - skin 1 [nTPM]":"13.6","Tissue RNA - small intestine [nTPM]":"19.5","Tissue RNA - smooth muscle [nTPM]":"13.6","Tissue RNA - spinal cord [nTPM]":"8.1","Tissue RNA - spleen [nTPM]":"12.0","Tissue RNA - stomach 1 [nTPM]":"20.3","Tissue RNA - testis [nTPM]":"8.9","Tissue RNA - thalamus [nTPM]":"12.9","Tissue RNA - thymus [nTPM]":"17.2","Tissue RNA - thyroid gland [nTPM]":"10.8","Tissue RNA - tongue [nTPM]":"10.3","Tissue RNA - tonsil [nTPM]":"17.4","Tissue RNA - urinary bladder [nTPM]":"16.2","Tissue RNA - vagina [nTPM]":"11.4","Tissue RNA - white matter [nTPM]":"8.6","Cell RNA - A-431 [nTPM]":"15.9","Cell RNA - A549 [nTPM]":"14.3","Cell RNA - AF22 [nTPM]":"39.4","Cell RNA - AN3-CA [nTPM]":"20.7","Cell RNA - ASC diff [nTPM]":"14.1","Cell RNA - ASC TERT1 [nTPM]":"19.9","Cell RNA - BEWO [nTPM]":"68.9","Cell RNA - BJ [nTPM]":"17.3","Cell RNA - BJ hTERT+ [nTPM]":"22.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.9","Cell RNA - CACO-2 [nTPM]":"51.5","Cell RNA - CAPAN-2 [nTPM]":"30.7","Cell RNA - Daudi [nTPM]":"38.7","Cell RNA - EFO-21 [nTPM]":"10.4","Cell RNA - fHDF\/TERT166 [nTPM]":"32.0","Cell RNA - GAMG [nTPM]":"23.4","Cell RNA - HaCaT [nTPM]":"18.6","Cell RNA - HAP1 [nTPM]":"44.9","Cell RNA - HBEC3-KT [nTPM]":"17.3","Cell RNA - HBF TERT88 [nTPM]":"34.3","Cell RNA - HDLM-2 [nTPM]":"26.7","Cell RNA - HEK 293 [nTPM]":"15.0","Cell RNA - HEL [nTPM]":"37.6","Cell RNA - HeLa [nTPM]":"17.6","Cell RNA - Hep G2 [nTPM]":"15.6","Cell RNA - HHSteC [nTPM]":"15.8","Cell RNA - HL-60 [nTPM]":"32.8","Cell RNA - HMC-1 [nTPM]":"25.6","Cell RNA - HSkMC [nTPM]":"18.1","Cell RNA - hTCEpi [nTPM]":"25.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.9","Cell RNA - hTERT-HME1 [nTPM]":"20.2","Cell RNA - hTERT-RPE1 [nTPM]":"33.6","Cell RNA - HUVEC TERT2 [nTPM]":"27.1","Cell RNA - JURKAT [nTPM]":"28.7","Cell RNA - K-562 [nTPM]":"28.0","Cell RNA - Karpas-707 [nTPM]":"17.3","Cell RNA - LHCN-M2 [nTPM]":"27.6","Cell RNA - MCF7 [nTPM]":"14.1","Cell RNA - MOLT-4 [nTPM]":"46.8","Cell RNA - NB-4 [nTPM]":"56.6","Cell RNA - NTERA-2 [nTPM]":"87.6","Cell RNA - OE19 [nTPM]":"25.3","Cell RNA - PC-3 [nTPM]":"7.4","Cell RNA - REH [nTPM]":"43.4","Cell RNA - RH-30 [nTPM]":"39.9","Cell RNA - RPMI-8226 [nTPM]":"59.9","Cell RNA - RPTEC TERT1 [nTPM]":"27.2","Cell RNA - RT4 [nTPM]":"22.4","Cell RNA - SCLC-21H [nTPM]":"11.2","Cell RNA - SH-SY5Y [nTPM]":"32.4","Cell RNA - SiHa [nTPM]":"20.5","Cell RNA - SK-BR-3 [nTPM]":"24.9","Cell RNA - SK-MEL-30 [nTPM]":"21.8","Cell RNA - SuSa [nTPM]":"97.4","Cell RNA - T-47d [nTPM]":"28.9","Cell RNA - THP-1 [nTPM]":"26.9","Cell RNA - TIME [nTPM]":"28.1","Cell RNA - U-138 MG [nTPM]":"18.7","Cell RNA - U-2 OS [nTPM]":"24.8","Cell RNA - U-2197 [nTPM]":"38.2","Cell RNA - U-251 MG [nTPM]":"22.0","Cell RNA - U-266\/70 [nTPM]":"16.4","Cell RNA - U-266\/84 [nTPM]":"28.5","Cell RNA - U-698 [nTPM]":"41.9","Cell RNA - U-87 MG [nTPM]":"15.4","Cell RNA - U-937 [nTPM]":"20.0","Cell RNA - WM-115 [nTPM]":"15.0","Blood RNA - basophil [nTPM]":"31.2","Blood RNA - classical monocyte [nTPM]":"8.1","Blood RNA - eosinophil [nTPM]":"13.7","Blood RNA - gdT-cell [nTPM]":"11.6","Blood RNA - intermediate monocyte [nTPM]":"16.4","Blood RNA - MAIT T-cell [nTPM]":"7.9","Blood RNA - memory B-cell [nTPM]":"10.7","Blood RNA - memory CD4 T-cell [nTPM]":"10.1","Blood RNA - memory CD8 T-cell [nTPM]":"13.1","Blood RNA - myeloid DC [nTPM]":"7.9","Blood RNA - naive B-cell [nTPM]":"10.5","Blood RNA - naive CD4 T-cell [nTPM]":"13.8","Blood RNA - naive CD8 T-cell [nTPM]":"12.4","Blood RNA - neutrophil [nTPM]":"19.2","Blood RNA - NK-cell [nTPM]":"11.2","Blood RNA - non-classical monocyte [nTPM]":"22.4","Blood RNA - plasmacytoid DC [nTPM]":"7.8","Blood RNA - T-reg [nTPM]":"7.6","Blood RNA - total PBMC [nTPM]":"5.8","Brain RNA - amygdala [nTPM]":"11.0","Brain RNA - basal ganglia [nTPM]":"12.2","Brain RNA - cerebellum [nTPM]":"11.7","Brain RNA - cerebral cortex [nTPM]":"12.3","Brain RNA - hippocampal formation [nTPM]":"12.5","Brain RNA - hypothalamus [nTPM]":"12.0","Brain RNA - medulla oblongata [nTPM]":"8.5","Brain RNA - midbrain [nTPM]":"9.7","Brain RNA - pons [nTPM]":"8.7","Brain RNA - spinal cord [nTPM]":"8.1","Brain RNA - thalamus [nTPM]":"12.9","Brain RNA - white matter [nTPM]":"8.6","Single Cell Type RNA - Adipocytes [nTPM]":"73.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"32.1","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"90.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"100.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"96.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"57.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"72.3","Single Cell Type RNA - Bipolar cells [nTPM]":"63.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"59.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"38.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"64.3","Single Cell Type RNA - Club cells [nTPM]":"53.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"73.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"94.2","Single Cell Type RNA - dendritic cells [nTPM]":"66.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"161.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"58.7","Single Cell Type RNA - Ductal cells [nTPM]":"77.5","Single Cell Type RNA - Early spermatids [nTPM]":"3.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"45.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"40.8","Single Cell Type RNA - Endothelial cells [nTPM]":"77.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"78.8","Single Cell Type RNA - Erythroid cells [nTPM]":"60.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"42.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"91.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.4","Single Cell Type RNA - Fibroblasts [nTPM]":"50.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"98.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"53.4","Single Cell Type RNA - granulocytes [nTPM]":"24.1","Single Cell Type RNA - Granulosa cells [nTPM]":"26.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"77.8","Single Cell Type RNA - Hepatocytes [nTPM]":"56.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"51.5","Single Cell Type RNA - Horizontal cells [nTPM]":"92.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"45.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"92.9","Single Cell Type RNA - Ionocytes [nTPM]":"36.7","Single Cell Type RNA - Kupffer cells [nTPM]":"53.9","Single Cell Type RNA - Langerhans cells [nTPM]":"83.7","Single Cell Type RNA - Late spermatids [nTPM]":"5.9","Single Cell Type RNA - Leydig cells [nTPM]":"40.7","Single Cell Type RNA - Macrophages [nTPM]":"75.3","Single Cell Type RNA - Melanocytes [nTPM]":"62.2","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"82.9","Single Cell Type RNA - Muller glia cells [nTPM]":"41.7","Single Cell Type RNA - NK-cells [nTPM]":"49.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"114.2","Single Cell Type RNA - Paneth cells [nTPM]":"104.7","Single Cell Type RNA - Peritubular cells [nTPM]":"51.6","Single Cell Type RNA - Plasma cells [nTPM]":"85.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"130.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"63.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"52.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"42.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"65.8","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"53.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"52.2","Single Cell Type RNA - Spermatocytes [nTPM]":"53.0","Single Cell Type RNA - Spermatogonia [nTPM]":"40.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"93.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"155.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"139.1","Single Cell Type RNA - T-cells [nTPM]":"83.0","Single Cell Type RNA - Theca cells [nTPM]":"36.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"96.7","Single Cell Type RNA - Urothelial cells [nTPM]":"176.9"},{"Gene":"MITF","Gene synonym":["bHLHe32","MI","WS2","WS2A"],"Ensembl":"ENSG00000187098","Gene description":"Melanocyte inducing transcription factor","Uniprot":["O75030"],"Chromosome":"3","Position":"69739464-69968336","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","DNA-binding"],"Disease involvement":["Albinism","Cancer-related genes","Deafness","Disease variant","Microphthalmia","Osteopetrosis","Waardenburg syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"133.5","Melanocytes":"585.2","Oligodendrocyte precursor cells":"166.9","Oligodendrocytes":"240.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"melanoma":"39.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"5.2","classical monocyte":"9.4","intermediate monocyte":"3.3","myeloid DC":"6.1","non-classical monocyte":"5.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"6.1","granulocytes":"5.2","monocytes":"9.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"89.1","SK-MEL-30":"254.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002578","HPA003259"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002578":"AB_564111","HPA003259":"AB_1079381"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.35e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Tissue RNA - adipose tissue [nTPM]":"13.8","Tissue RNA - adrenal gland [nTPM]":"4.4","Tissue RNA - amygdala [nTPM]":"5.1","Tissue RNA - appendix [nTPM]":"3.8","Tissue RNA - basal ganglia [nTPM]":"9.2","Tissue RNA - bone marrow [nTPM]":"1.7","Tissue RNA - breast [nTPM]":"10.0","Tissue RNA - cerebellum [nTPM]":"9.4","Tissue RNA - cerebral cortex [nTPM]":"6.3","Tissue RNA - cervix [nTPM]":"51.3","Tissue RNA - choroid plexus [nTPM]":"21.2","Tissue RNA - colon [nTPM]":"18.8","Tissue RNA - duodenum [nTPM]":"2.8","Tissue RNA - endometrium 1 [nTPM]":"46.2","Tissue RNA - epididymis [nTPM]":"4.5","Tissue RNA - esophagus [nTPM]":"8.9","Tissue RNA - fallopian tube [nTPM]":"10.3","Tissue RNA - gallbladder [nTPM]":"16.8","Tissue RNA - heart muscle [nTPM]":"31.1","Tissue RNA - hippocampal formation [nTPM]":"5.2","Tissue RNA - hypothalamus [nTPM]":"9.3","Tissue RNA - kidney [nTPM]":"20.0","Tissue RNA - liver [nTPM]":"2.2","Tissue RNA - lung [nTPM]":"9.7","Tissue RNA - lymph node [nTPM]":"3.4","Tissue RNA - medulla oblongata [nTPM]":"12.5","Tissue RNA - midbrain [nTPM]":"9.5","Tissue RNA - ovary [nTPM]":"18.7","Tissue RNA - pancreas [nTPM]":"4.2","Tissue RNA - parathyroid gland [nTPM]":"16.8","Tissue RNA - pituitary gland [nTPM]":"3.8","Tissue RNA - placenta [nTPM]":"3.3","Tissue RNA - pons [nTPM]":"10.4","Tissue RNA - prostate [nTPM]":"8.4","Tissue RNA - rectum [nTPM]":"4.5","Tissue RNA - retina [nTPM]":"1.2","Tissue RNA - salivary gland [nTPM]":"5.1","Tissue RNA - seminal vesicle [nTPM]":"14.1","Tissue RNA - skeletal muscle [nTPM]":"50.6","Tissue RNA - skin 1 [nTPM]":"11.0","Tissue RNA - small intestine [nTPM]":"5.8","Tissue RNA - smooth muscle [nTPM]":"46.0","Tissue RNA - spinal cord [nTPM]":"7.0","Tissue RNA - spleen [nTPM]":"2.0","Tissue RNA - stomach 1 [nTPM]":"9.4","Tissue RNA - testis [nTPM]":"2.3","Tissue RNA - thalamus [nTPM]":"10.3","Tissue RNA - thymus [nTPM]":"2.2","Tissue RNA - thyroid gland [nTPM]":"7.6","Tissue RNA - tongue [nTPM]":"43.3","Tissue RNA - tonsil [nTPM]":"1.5","Tissue RNA - urinary bladder [nTPM]":"10.6","Tissue RNA - vagina [nTPM]":"16.6","Tissue RNA - white matter [nTPM]":"13.8","Cell RNA - A-431 [nTPM]":"17.2","Cell RNA - A549 [nTPM]":"12.2","Cell RNA - AF22 [nTPM]":"1.3","Cell RNA - AN3-CA [nTPM]":"5.1","Cell RNA - ASC diff [nTPM]":"18.8","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"2.0","Cell RNA - BJ [nTPM]":"16.9","Cell RNA - BJ hTERT+ [nTPM]":"9.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.8","Cell RNA - CACO-2 [nTPM]":"6.1","Cell RNA - CAPAN-2 [nTPM]":"0.8","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"4.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.3","Cell RNA - GAMG [nTPM]":"21.6","Cell RNA - HaCaT [nTPM]":"8.6","Cell RNA - HAP1 [nTPM]":"3.7","Cell RNA - HBEC3-KT [nTPM]":"9.4","Cell RNA - HBF TERT88 [nTPM]":"8.6","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"2.5","Cell RNA - HEL [nTPM]":"37.1","Cell RNA - HeLa [nTPM]":"24.5","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"4.5","Cell RNA - HL-60 [nTPM]":"0.8","Cell RNA - HMC-1 [nTPM]":"89.1","Cell RNA - HSkMC [nTPM]":"15.3","Cell RNA - hTCEpi [nTPM]":"3.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.2","Cell RNA - hTERT-HME1 [nTPM]":"8.6","Cell RNA - hTERT-RPE1 [nTPM]":"29.1","Cell RNA - HUVEC TERT2 [nTPM]":"2.4","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"12.3","Cell RNA - Karpas-707 [nTPM]":"5.2","Cell RNA - LHCN-M2 [nTPM]":"5.4","Cell RNA - MCF7 [nTPM]":"1.2","Cell RNA - MOLT-4 [nTPM]":"0.7","Cell RNA - NB-4 [nTPM]":"1.0","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"0.7","Cell RNA - PC-3 [nTPM]":"8.3","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"1.9","Cell RNA - RPMI-8226 [nTPM]":"7.7","Cell RNA - RPTEC TERT1 [nTPM]":"45.2","Cell RNA - RT4 [nTPM]":"9.0","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"1.9","Cell RNA - SiHa [nTPM]":"8.8","Cell RNA - SK-BR-3 [nTPM]":"3.1","Cell RNA - SK-MEL-30 [nTPM]":"254.1","Cell RNA - SuSa [nTPM]":"2.0","Cell RNA - T-47d [nTPM]":"0.7","Cell RNA - THP-1 [nTPM]":"2.3","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"3.8","Cell RNA - U-2 OS [nTPM]":"13.3","Cell RNA - U-2197 [nTPM]":"5.1","Cell RNA - U-251 MG [nTPM]":"3.5","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"1.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"7.7","Cell RNA - U-937 [nTPM]":"2.6","Cell RNA - WM-115 [nTPM]":"9.2","Blood RNA - basophil [nTPM]":"5.2","Blood RNA - classical monocyte [nTPM]":"9.4","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"3.3","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"6.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"5.9","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"3.1","Brain RNA - amygdala [nTPM]":"5.1","Brain RNA - basal ganglia [nTPM]":"9.2","Brain RNA - cerebellum [nTPM]":"9.4","Brain RNA - cerebral cortex [nTPM]":"6.3","Brain RNA - hippocampal formation [nTPM]":"5.2","Brain RNA - hypothalamus [nTPM]":"9.3","Brain RNA - medulla oblongata [nTPM]":"12.5","Brain RNA - midbrain [nTPM]":"9.5","Brain RNA - pons [nTPM]":"10.4","Brain RNA - spinal cord [nTPM]":"7.0","Brain RNA - thalamus [nTPM]":"10.3","Brain RNA - white matter [nTPM]":"13.8","Single Cell Type RNA - Adipocytes [nTPM]":"4.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.8","Single Cell Type RNA - Astrocytes [nTPM]":"34.3","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"42.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"1.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"109.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"18.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"50.9","Single Cell Type RNA - Ductal cells [nTPM]":"14.7","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"24.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"94.3","Single Cell Type RNA - Endothelial cells [nTPM]":"7.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"8.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.0","Single Cell Type RNA - Fibroblasts [nTPM]":"38.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"71.2","Single Cell Type RNA - granulocytes [nTPM]":"106.8","Single Cell Type RNA - Granulosa cells [nTPM]":"10.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.6","Single Cell Type RNA - Hepatocytes [nTPM]":"2.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"45.8","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"133.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"30.8","Single Cell Type RNA - Langerhans cells [nTPM]":"30.9","Single Cell Type RNA - Late spermatids [nTPM]":"3.4","Single Cell Type RNA - Leydig cells [nTPM]":"44.4","Single Cell Type RNA - Macrophages [nTPM]":"24.3","Single Cell Type RNA - Melanocytes [nTPM]":"585.2","Single Cell Type RNA - Microglial cells [nTPM]":"50.6","Single Cell Type RNA - monocytes [nTPM]":"10.6","Single Cell Type RNA - Muller glia cells [nTPM]":"1.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"166.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"240.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"50.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.6","Single Cell Type RNA - Spermatocytes [nTPM]":"4.0","Single Cell Type RNA - Spermatogonia [nTPM]":"6.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"3.8","Single Cell Type RNA - Theca cells [nTPM]":"5.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"7.1"},{"Gene":"MYC","Gene synonym":["bHLHe39","c-Myc","MYCC"],"Ensembl":"ENSG00000136997","Gene description":"MYC proto-oncogene, bHLH transcription factor","Uniprot":["P01106"],"Chromosome":"8","Position":"127735434-127742951","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"254.6","skin 1":"289.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"1013.3","Basal prostatic cells":"1080.5","Basal squamous epithelial cells":"1270.8","Squamous epithelial cells":"768.8","Suprabasal keratinocytes":"1070.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RPMI-8226":"1069.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000084","CAB010307","HPA055893","HPA066556"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 61: Squamous epithelial cells - Keratinization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB000084":null,"CAB010307":"AB_631274","HPA055893":"AB_2682960","HPA066556":"AB_2685691"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.52e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.49e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.96e-5"},"Tissue RNA - adipose tissue [nTPM]":"254.6","Tissue RNA - adrenal gland [nTPM]":"59.8","Tissue RNA - amygdala [nTPM]":"2.6","Tissue RNA - appendix [nTPM]":"62.3","Tissue RNA - basal ganglia [nTPM]":"2.2","Tissue RNA - bone marrow [nTPM]":"53.7","Tissue RNA - breast [nTPM]":"115.8","Tissue RNA - cerebellum [nTPM]":"3.7","Tissue RNA - cerebral cortex [nTPM]":"3.3","Tissue RNA - cervix [nTPM]":"54.4","Tissue RNA - choroid plexus [nTPM]":"3.0","Tissue RNA - colon [nTPM]":"57.9","Tissue RNA - duodenum [nTPM]":"30.6","Tissue RNA - endometrium 1 [nTPM]":"53.8","Tissue RNA - epididymis [nTPM]":"3.8","Tissue RNA - esophagus [nTPM]":"99.5","Tissue RNA - fallopian tube [nTPM]":"167.5","Tissue RNA - gallbladder [nTPM]":"83.3","Tissue RNA - heart muscle [nTPM]":"45.5","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"6.3","Tissue RNA - kidney [nTPM]":"20.0","Tissue RNA - liver [nTPM]":"64.9","Tissue RNA - lung [nTPM]":"47.0","Tissue RNA - lymph node [nTPM]":"49.4","Tissue RNA - medulla oblongata [nTPM]":"9.2","Tissue RNA - midbrain [nTPM]":"5.0","Tissue RNA - ovary [nTPM]":"100.0","Tissue RNA - pancreas [nTPM]":"103.1","Tissue RNA - parathyroid gland [nTPM]":"7.0","Tissue RNA - pituitary gland [nTPM]":"12.3","Tissue RNA - placenta [nTPM]":"33.4","Tissue RNA - pons [nTPM]":"6.0","Tissue RNA - prostate [nTPM]":"32.7","Tissue RNA - rectum [nTPM]":"36.8","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"42.2","Tissue RNA - seminal vesicle [nTPM]":"14.1","Tissue RNA - skeletal muscle [nTPM]":"50.6","Tissue RNA - skin 1 [nTPM]":"289.1","Tissue RNA - small intestine [nTPM]":"48.6","Tissue RNA - smooth muscle [nTPM]":"54.8","Tissue RNA - spinal cord [nTPM]":"4.5","Tissue RNA - spleen [nTPM]":"60.1","Tissue RNA - stomach 1 [nTPM]":"70.6","Tissue RNA - testis [nTPM]":"12.5","Tissue RNA - thalamus [nTPM]":"5.5","Tissue RNA - thymus [nTPM]":"47.2","Tissue RNA - thyroid gland [nTPM]":"27.0","Tissue RNA - tongue [nTPM]":"15.7","Tissue RNA - tonsil [nTPM]":"39.2","Tissue RNA - urinary bladder [nTPM]":"63.2","Tissue RNA - vagina [nTPM]":"96.3","Tissue RNA - white matter [nTPM]":"4.4","Cell RNA - A-431 [nTPM]":"56.8","Cell RNA - A549 [nTPM]":"89.3","Cell RNA - AF22 [nTPM]":"9.3","Cell RNA - AN3-CA [nTPM]":"100.9","Cell RNA - ASC diff [nTPM]":"166.6","Cell RNA - ASC TERT1 [nTPM]":"209.8","Cell RNA - BEWO [nTPM]":"28.4","Cell RNA - BJ [nTPM]":"72.2","Cell RNA - BJ hTERT+ [nTPM]":"31.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"87.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"72.7","Cell RNA - CACO-2 [nTPM]":"137.0","Cell RNA - CAPAN-2 [nTPM]":"150.2","Cell RNA - Daudi [nTPM]":"587.3","Cell RNA - EFO-21 [nTPM]":"86.4","Cell RNA - fHDF\/TERT166 [nTPM]":"43.0","Cell RNA - GAMG [nTPM]":"82.4","Cell RNA - HaCaT [nTPM]":"122.2","Cell RNA - HAP1 [nTPM]":"383.8","Cell RNA - HBEC3-KT [nTPM]":"226.5","Cell RNA - HBF TERT88 [nTPM]":"67.8","Cell RNA - HDLM-2 [nTPM]":"128.9","Cell RNA - HEK 293 [nTPM]":"167.0","Cell RNA - HEL [nTPM]":"370.7","Cell RNA - HeLa [nTPM]":"189.5","Cell RNA - Hep G2 [nTPM]":"203.6","Cell RNA - HHSteC [nTPM]":"150.0","Cell RNA - HL-60 [nTPM]":"282.0","Cell RNA - HMC-1 [nTPM]":"52.0","Cell RNA - HSkMC [nTPM]":"138.8","Cell RNA - hTCEpi [nTPM]":"560.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"55.5","Cell RNA - hTERT-HME1 [nTPM]":"490.8","Cell RNA - hTERT-RPE1 [nTPM]":"74.8","Cell RNA - HUVEC TERT2 [nTPM]":"104.3","Cell RNA - JURKAT [nTPM]":"217.3","Cell RNA - K-562 [nTPM]":"549.8","Cell RNA - Karpas-707 [nTPM]":"315.5","Cell RNA - LHCN-M2 [nTPM]":"49.7","Cell RNA - MCF7 [nTPM]":"151.9","Cell RNA - MOLT-4 [nTPM]":"394.4","Cell RNA - NB-4 [nTPM]":"616.9","Cell RNA - NTERA-2 [nTPM]":"27.4","Cell RNA - OE19 [nTPM]":"273.2","Cell RNA - PC-3 [nTPM]":"204.0","Cell RNA - REH [nTPM]":"203.7","Cell RNA - RH-30 [nTPM]":"46.1","Cell RNA - RPMI-8226 [nTPM]":"1069.6","Cell RNA - RPTEC TERT1 [nTPM]":"79.2","Cell RNA - RT4 [nTPM]":"61.9","Cell RNA - SCLC-21H [nTPM]":"660.7","Cell RNA - SH-SY5Y [nTPM]":"64.9","Cell RNA - SiHa [nTPM]":"32.6","Cell RNA - SK-BR-3 [nTPM]":"270.7","Cell RNA - SK-MEL-30 [nTPM]":"195.9","Cell RNA - SuSa [nTPM]":"17.5","Cell RNA - T-47d [nTPM]":"106.4","Cell RNA - THP-1 [nTPM]":"172.2","Cell RNA - TIME [nTPM]":"120.5","Cell RNA - U-138 MG [nTPM]":"63.4","Cell RNA - U-2 OS [nTPM]":"71.6","Cell RNA - U-2197 [nTPM]":"49.7","Cell RNA - U-251 MG [nTPM]":"87.2","Cell RNA - U-266\/70 [nTPM]":"5.5","Cell RNA - U-266\/84 [nTPM]":"8.7","Cell RNA - U-698 [nTPM]":"275.9","Cell RNA - U-87 MG [nTPM]":"55.3","Cell RNA - U-937 [nTPM]":"286.2","Cell RNA - WM-115 [nTPM]":"30.8","Blood RNA - basophil [nTPM]":"3.0","Blood RNA - classical monocyte [nTPM]":"39.5","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"31.5","Blood RNA - intermediate monocyte [nTPM]":"36.0","Blood RNA - MAIT T-cell [nTPM]":"161.5","Blood RNA - memory B-cell [nTPM]":"92.0","Blood RNA - memory CD4 T-cell [nTPM]":"114.3","Blood RNA - memory CD8 T-cell [nTPM]":"67.4","Blood RNA - myeloid DC [nTPM]":"33.5","Blood RNA - naive B-cell [nTPM]":"71.4","Blood RNA - naive CD4 T-cell [nTPM]":"195.2","Blood RNA - naive CD8 T-cell [nTPM]":"128.0","Blood RNA - neutrophil [nTPM]":"4.1","Blood RNA - NK-cell [nTPM]":"85.5","Blood RNA - non-classical monocyte [nTPM]":"26.9","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"95.6","Blood RNA - total PBMC [nTPM]":"88.9","Brain RNA - amygdala [nTPM]":"2.6","Brain RNA - basal ganglia [nTPM]":"2.2","Brain RNA - cerebellum [nTPM]":"3.7","Brain RNA - cerebral cortex [nTPM]":"3.3","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"6.3","Brain RNA - medulla oblongata [nTPM]":"9.2","Brain RNA - midbrain [nTPM]":"5.0","Brain RNA - pons [nTPM]":"6.0","Brain RNA - spinal cord [nTPM]":"4.5","Brain RNA - thalamus [nTPM]":"5.5","Brain RNA - white matter [nTPM]":"4.4","Single Cell Type RNA - Adipocytes [nTPM]":"218.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"57.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"70.4","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"108.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1013.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1080.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"278.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1270.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"251.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"207.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"44.3","Single Cell Type RNA - Club cells [nTPM]":"98.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.6","Single Cell Type RNA - dendritic cells [nTPM]":"20.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"78.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"43.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"224.5","Single Cell Type RNA - Endothelial cells [nTPM]":"158.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.5","Single Cell Type RNA - Erythroid cells [nTPM]":"189.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"43.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"61.2","Single Cell Type RNA - Fibroblasts [nTPM]":"337.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"46.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"72.0","Single Cell Type RNA - granulocytes [nTPM]":"57.0","Single Cell Type RNA - Granulosa cells [nTPM]":"47.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"141.0","Single Cell Type RNA - Hepatocytes [nTPM]":"25.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"26.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"67.8","Single Cell Type RNA - Ionocytes [nTPM]":"97.6","Single Cell Type RNA - Kupffer cells [nTPM]":"43.7","Single Cell Type RNA - Langerhans cells [nTPM]":"133.1","Single Cell Type RNA - Late spermatids [nTPM]":"3.9","Single Cell Type RNA - Leydig cells [nTPM]":"98.8","Single Cell Type RNA - Macrophages [nTPM]":"23.3","Single Cell Type RNA - Melanocytes [nTPM]":"168.9","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"17.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.4","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"66.5","Single Cell Type RNA - Paneth cells [nTPM]":"40.4","Single Cell Type RNA - Peritubular cells [nTPM]":"67.4","Single Cell Type RNA - Plasma cells [nTPM]":"45.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"364.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"458.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"349.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"768.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1070.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.9","Single Cell Type RNA - T-cells [nTPM]":"75.0","Single Cell Type RNA - Theca cells [nTPM]":"56.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"117.7","Single Cell Type RNA - Urothelial cells [nTPM]":"409.4"},{"Gene":"NAV3","Gene synonym":["KIAA0938","POMFIL1"],"Ensembl":"ENSG00000067798","Gene description":"Neuron navigator 3","Uniprot":["Q8IVL0"],"Chromosome":"12","Position":"77324641-78213010","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"17.3","ovary":"18.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Astrocytes":"882.1","Excitatory neurons":"1473.6","Inhibitory neurons":"753.8","Microglial cells":"534.0","Oligodendrocyte precursor cells":"786.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"8","RNA brain regional specific nTPM":{"amygdala":"9.7","basal ganglia":"15.0","cerebral cortex":"17.3","hippocampal formation":"13.6","white matter":"10.3"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"1.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTEC\/SVTERT24-B":"47.0","THP-1":"41.8","U-138 MG":"30.8","WM-115":"38.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032111","HPA061392"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA032111":"AB_10603881","HPA061392":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.86e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-3"},"Tissue RNA - adipose tissue [nTPM]":"3.8","Tissue RNA - adrenal gland [nTPM]":"4.8","Tissue RNA - amygdala [nTPM]":"9.7","Tissue RNA - appendix [nTPM]":"1.0","Tissue RNA - basal ganglia [nTPM]":"15.0","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"4.0","Tissue RNA - cerebellum [nTPM]":"0.9","Tissue RNA - cerebral cortex [nTPM]":"17.3","Tissue RNA - cervix [nTPM]":"1.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.7","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"2.0","Tissue RNA - epididymis [nTPM]":"2.9","Tissue RNA - esophagus [nTPM]":"1.9","Tissue RNA - fallopian tube [nTPM]":"2.2","Tissue RNA - gallbladder [nTPM]":"5.1","Tissue RNA - heart muscle [nTPM]":"1.9","Tissue RNA - hippocampal formation [nTPM]":"13.6","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"1.0","Tissue RNA - lung [nTPM]":"3.3","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"0.7","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"18.3","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"3.1","Tissue RNA - placenta [nTPM]":"2.2","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"2.1","Tissue RNA - rectum [nTPM]":"0.8","Tissue RNA - retina [nTPM]":"5.2","Tissue RNA - salivary gland [nTPM]":"0.9","Tissue RNA - seminal vesicle [nTPM]":"2.5","Tissue RNA - skeletal muscle [nTPM]":"1.3","Tissue RNA - skin 1 [nTPM]":"2.6","Tissue RNA - small intestine [nTPM]":"0.6","Tissue RNA - smooth muscle [nTPM]":"2.5","Tissue RNA - spinal cord [nTPM]":"1.4","Tissue RNA - spleen [nTPM]":"8.0","Tissue RNA - stomach 1 [nTPM]":"0.8","Tissue RNA - testis [nTPM]":"2.8","Tissue RNA - thalamus [nTPM]":"1.6","Tissue RNA - thymus [nTPM]":"1.9","Tissue RNA - thyroid gland [nTPM]":"1.2","Tissue RNA - tongue [nTPM]":"3.4","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"3.3","Tissue RNA - vagina [nTPM]":"1.7","Tissue RNA - white matter [nTPM]":"10.3","Cell RNA - A-431 [nTPM]":"3.5","Cell RNA - A549 [nTPM]":"8.7","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"8.5","Cell RNA - ASC TERT1 [nTPM]":"18.1","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"26.5","Cell RNA - BJ hTERT+ [nTPM]":"20.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.3","Cell RNA - CACO-2 [nTPM]":"1.7","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"1.9","Cell RNA - fHDF\/TERT166 [nTPM]":"22.0","Cell RNA - GAMG [nTPM]":"7.2","Cell RNA - HaCaT [nTPM]":"2.5","Cell RNA - HAP1 [nTPM]":"7.8","Cell RNA - HBEC3-KT [nTPM]":"4.0","Cell RNA - HBF TERT88 [nTPM]":"19.3","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"3.9","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"6.7","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"6.2","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"47.0","Cell RNA - hTERT-HME1 [nTPM]":"11.1","Cell RNA - hTERT-RPE1 [nTPM]":"9.3","Cell RNA - HUVEC TERT2 [nTPM]":"16.4","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"26.2","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"12.0","Cell RNA - NTERA-2 [nTPM]":"2.7","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"2.1","Cell RNA - REH [nTPM]":"1.0","Cell RNA - RH-30 [nTPM]":"2.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"1.7","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"1.6","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"3.5","Cell RNA - SuSa [nTPM]":"0.8","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"41.8","Cell RNA - TIME [nTPM]":"14.1","Cell RNA - U-138 MG [nTPM]":"30.8","Cell RNA - U-2 OS [nTPM]":"8.1","Cell RNA - U-2197 [nTPM]":"12.0","Cell RNA - U-251 MG [nTPM]":"18.2","Cell RNA - U-266\/70 [nTPM]":"1.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.7","Cell RNA - U-87 MG [nTPM]":"8.8","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"38.7","Blood RNA - basophil [nTPM]":"0.8","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"9.7","Brain RNA - basal ganglia [nTPM]":"15.0","Brain RNA - cerebellum [nTPM]":"0.9","Brain RNA - cerebral cortex [nTPM]":"17.3","Brain RNA - hippocampal formation [nTPM]":"13.6","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.7","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"1.4","Brain RNA - thalamus [nTPM]":"1.6","Brain RNA - white matter [nTPM]":"10.3","Single Cell Type RNA - Adipocytes [nTPM]":"11.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.0","Single Cell Type RNA - Astrocytes [nTPM]":"882.1","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"5.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"7.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.2","Single Cell Type RNA - Early spermatids [nTPM]":"10.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.2","Single Cell Type RNA - Endothelial cells [nTPM]":"5.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1473.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"18.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.3","Single Cell Type RNA - granulocytes [nTPM]":"11.4","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.3","Single Cell Type RNA - Horizontal cells [nTPM]":"50.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"753.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"3.7","Single Cell Type RNA - Late spermatids [nTPM]":"4.7","Single Cell Type RNA - Leydig cells [nTPM]":"23.9","Single Cell Type RNA - Macrophages [nTPM]":"1.4","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"534.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"18.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"786.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"144.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"1.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"28.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"1.3","Single Cell Type RNA - Theca cells [nTPM]":"73.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"2.9"},{"Gene":"NRAS","Gene synonym":["N-ras"],"Ensembl":"ENSG00000213281","Gene description":"NRAS proto-oncogene, GTPase","Uniprot":["P01111"],"Chromosome":"1","Position":"114704469-114716771","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010157","HPA049830","CAB079912"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 16: Pancreatic endocrine cells - Mixed function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB010157":"AB_632073","CAB079912":"AB_2784586","HPA049830":"AB_2680903"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.59e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.03e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.36e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.87e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Tissue RNA - adipose tissue [nTPM]":"19.0","Tissue RNA - adrenal gland [nTPM]":"9.1","Tissue RNA - amygdala [nTPM]":"10.3","Tissue RNA - appendix [nTPM]":"25.7","Tissue RNA - basal ganglia [nTPM]":"11.2","Tissue RNA - bone marrow [nTPM]":"58.5","Tissue RNA - breast [nTPM]":"18.0","Tissue RNA - cerebellum [nTPM]":"11.5","Tissue RNA - cerebral cortex [nTPM]":"12.3","Tissue RNA - cervix [nTPM]":"12.5","Tissue RNA - choroid plexus [nTPM]":"8.6","Tissue RNA - colon [nTPM]":"27.8","Tissue RNA - duodenum [nTPM]":"21.5","Tissue RNA - endometrium 1 [nTPM]":"12.4","Tissue RNA - epididymis [nTPM]":"7.8","Tissue RNA - esophagus [nTPM]":"20.7","Tissue RNA - fallopian tube [nTPM]":"10.3","Tissue RNA - gallbladder [nTPM]":"17.2","Tissue RNA - heart muscle [nTPM]":"8.3","Tissue RNA - hippocampal formation [nTPM]":"10.2","Tissue RNA - hypothalamus [nTPM]":"12.2","Tissue RNA - kidney [nTPM]":"20.9","Tissue RNA - liver [nTPM]":"24.9","Tissue RNA - lung [nTPM]":"18.5","Tissue RNA - lymph node [nTPM]":"30.4","Tissue RNA - medulla oblongata [nTPM]":"12.3","Tissue RNA - midbrain [nTPM]":"12.1","Tissue RNA - ovary [nTPM]":"9.6","Tissue RNA - pancreas [nTPM]":"11.4","Tissue RNA - parathyroid gland [nTPM]":"9.0","Tissue RNA - pituitary gland [nTPM]":"4.3","Tissue RNA - placenta [nTPM]":"28.3","Tissue RNA - pons [nTPM]":"12.3","Tissue RNA - prostate [nTPM]":"11.4","Tissue RNA - rectum [nTPM]":"26.6","Tissue RNA - retina [nTPM]":"6.6","Tissue RNA - salivary gland [nTPM]":"10.9","Tissue RNA - seminal vesicle [nTPM]":"7.1","Tissue RNA - skeletal muscle [nTPM]":"7.7","Tissue RNA - skin 1 [nTPM]":"19.8","Tissue RNA - small intestine [nTPM]":"22.5","Tissue RNA - smooth muscle [nTPM]":"14.1","Tissue RNA - spinal cord [nTPM]":"11.7","Tissue RNA - spleen [nTPM]":"18.6","Tissue RNA - stomach 1 [nTPM]":"21.8","Tissue RNA - testis [nTPM]":"9.6","Tissue RNA - thalamus [nTPM]":"11.4","Tissue RNA - thymus [nTPM]":"39.0","Tissue RNA - thyroid gland [nTPM]":"16.1","Tissue RNA - tongue [nTPM]":"7.8","Tissue RNA - tonsil [nTPM]":"29.7","Tissue RNA - urinary bladder [nTPM]":"22.2","Tissue RNA - vagina [nTPM]":"8.6","Tissue RNA - white matter [nTPM]":"13.4","Cell RNA - A-431 [nTPM]":"93.7","Cell RNA - A549 [nTPM]":"24.9","Cell RNA - AF22 [nTPM]":"65.2","Cell RNA - AN3-CA [nTPM]":"24.9","Cell RNA - ASC diff [nTPM]":"26.4","Cell RNA - ASC TERT1 [nTPM]":"56.3","Cell RNA - BEWO [nTPM]":"46.5","Cell RNA - BJ [nTPM]":"43.5","Cell RNA - BJ hTERT+ [nTPM]":"48.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"79.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"89.0","Cell RNA - CACO-2 [nTPM]":"50.4","Cell RNA - CAPAN-2 [nTPM]":"33.9","Cell RNA - Daudi [nTPM]":"70.4","Cell RNA - EFO-21 [nTPM]":"56.3","Cell RNA - fHDF\/TERT166 [nTPM]":"58.9","Cell RNA - GAMG [nTPM]":"55.4","Cell RNA - HaCaT [nTPM]":"26.0","Cell RNA - HAP1 [nTPM]":"88.2","Cell RNA - HBEC3-KT [nTPM]":"70.6","Cell RNA - HBF TERT88 [nTPM]":"113.4","Cell RNA - HDLM-2 [nTPM]":"96.5","Cell RNA - HEK 293 [nTPM]":"34.2","Cell RNA - HEL [nTPM]":"47.8","Cell RNA - HeLa [nTPM]":"34.5","Cell RNA - Hep G2 [nTPM]":"60.2","Cell RNA - HHSteC [nTPM]":"52.3","Cell RNA - HL-60 [nTPM]":"120.0","Cell RNA - HMC-1 [nTPM]":"71.0","Cell RNA - HSkMC [nTPM]":"51.1","Cell RNA - hTCEpi [nTPM]":"56.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"91.5","Cell RNA - hTERT-HME1 [nTPM]":"66.2","Cell RNA - hTERT-RPE1 [nTPM]":"25.0","Cell RNA - HUVEC TERT2 [nTPM]":"102.8","Cell RNA - JURKAT [nTPM]":"54.6","Cell RNA - K-562 [nTPM]":"77.3","Cell RNA - Karpas-707 [nTPM]":"78.5","Cell RNA - LHCN-M2 [nTPM]":"71.0","Cell RNA - MCF7 [nTPM]":"248.9","Cell RNA - MOLT-4 [nTPM]":"83.5","Cell RNA - NB-4 [nTPM]":"46.4","Cell RNA - NTERA-2 [nTPM]":"111.0","Cell RNA - OE19 [nTPM]":"30.2","Cell RNA - PC-3 [nTPM]":"17.9","Cell RNA - REH [nTPM]":"62.9","Cell RNA - RH-30 [nTPM]":"116.0","Cell RNA - RPMI-8226 [nTPM]":"44.1","Cell RNA - RPTEC TERT1 [nTPM]":"70.6","Cell RNA - RT4 [nTPM]":"49.5","Cell RNA - SCLC-21H [nTPM]":"39.4","Cell RNA - SH-SY5Y [nTPM]":"59.0","Cell RNA - SiHa [nTPM]":"44.7","Cell RNA - SK-BR-3 [nTPM]":"36.4","Cell RNA - SK-MEL-30 [nTPM]":"107.1","Cell RNA - SuSa [nTPM]":"75.4","Cell RNA - T-47d [nTPM]":"31.9","Cell RNA - THP-1 [nTPM]":"96.2","Cell RNA - TIME [nTPM]":"79.2","Cell RNA - U-138 MG [nTPM]":"43.3","Cell RNA - U-2 OS [nTPM]":"82.2","Cell RNA - U-2197 [nTPM]":"81.5","Cell RNA - U-251 MG [nTPM]":"90.3","Cell RNA - U-266\/70 [nTPM]":"137.7","Cell RNA - U-266\/84 [nTPM]":"101.6","Cell RNA - U-698 [nTPM]":"81.6","Cell RNA - U-87 MG [nTPM]":"86.4","Cell RNA - U-937 [nTPM]":"64.6","Cell RNA - WM-115 [nTPM]":"159.0","Blood RNA - basophil [nTPM]":"38.7","Blood RNA - classical monocyte [nTPM]":"12.8","Blood RNA - eosinophil [nTPM]":"12.6","Blood RNA - gdT-cell [nTPM]":"11.7","Blood RNA - intermediate monocyte [nTPM]":"19.2","Blood RNA - MAIT T-cell [nTPM]":"10.5","Blood RNA - memory B-cell [nTPM]":"12.8","Blood RNA - memory CD4 T-cell [nTPM]":"9.3","Blood RNA - memory CD8 T-cell [nTPM]":"11.6","Blood RNA - myeloid DC [nTPM]":"12.6","Blood RNA - naive B-cell [nTPM]":"10.5","Blood RNA - naive CD4 T-cell [nTPM]":"9.9","Blood RNA - naive CD8 T-cell [nTPM]":"12.9","Blood RNA - neutrophil [nTPM]":"3.4","Blood RNA - NK-cell [nTPM]":"15.5","Blood RNA - non-classical monocyte [nTPM]":"17.6","Blood RNA - plasmacytoid DC [nTPM]":"9.6","Blood RNA - T-reg [nTPM]":"13.4","Blood RNA - total PBMC [nTPM]":"13.1","Brain RNA - amygdala [nTPM]":"10.3","Brain RNA - basal ganglia [nTPM]":"11.2","Brain RNA - cerebellum [nTPM]":"11.5","Brain RNA - cerebral cortex [nTPM]":"12.3","Brain RNA - hippocampal formation [nTPM]":"10.2","Brain RNA - hypothalamus [nTPM]":"12.2","Brain RNA - medulla oblongata [nTPM]":"12.3","Brain RNA - midbrain [nTPM]":"12.1","Brain RNA - pons [nTPM]":"12.3","Brain RNA - spinal cord [nTPM]":"11.7","Brain RNA - thalamus [nTPM]":"11.4","Brain RNA - white matter [nTPM]":"13.4","Single Cell Type RNA - Adipocytes [nTPM]":"22.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.5","Single Cell Type RNA - Astrocytes [nTPM]":"8.1","Single Cell Type RNA - B-cells [nTPM]":"25.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"31.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"23.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Bipolar cells [nTPM]":"5.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"19.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"22.4","Single Cell Type RNA - dendritic cells [nTPM]":"27.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"49.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"34.1","Single Cell Type RNA - Early spermatids [nTPM]":"3.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.7","Single Cell Type RNA - Endothelial cells [nTPM]":"29.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"24.6","Single Cell Type RNA - Erythroid cells [nTPM]":"31.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"31.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"50.4","Single Cell Type RNA - Fibroblasts [nTPM]":"16.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"29.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"38.0","Single Cell Type RNA - granulocytes [nTPM]":"31.1","Single Cell Type RNA - Granulosa cells [nTPM]":"22.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"33.2","Single Cell Type RNA - Hepatocytes [nTPM]":"29.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"49.2","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.1","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"44.9","Single Cell Type RNA - Langerhans cells [nTPM]":"30.7","Single Cell Type RNA - Late spermatids [nTPM]":"5.9","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"30.4","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"41.6","Single Cell Type RNA - Muller glia cells [nTPM]":"7.8","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"51.4","Single Cell Type RNA - Paneth cells [nTPM]":"32.9","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"39.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"39.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.3","Single Cell Type RNA - Spermatocytes [nTPM]":"7.3","Single Cell Type RNA - Spermatogonia [nTPM]":"15.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"36.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.2","Single Cell Type RNA - T-cells [nTPM]":"21.9","Single Cell Type RNA - Theca cells [nTPM]":"13.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"28.8","Single Cell Type RNA - Urothelial cells [nTPM]":"40.2"},{"Gene":"PTCH1","Gene synonym":["BCNS","NBCCS","PTCH"],"Ensembl":"ENSG00000185920","Gene description":"Patched 1","Uniprot":["Q13635"],"Chromosome":"9","Position":"95442980-95517057","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","Holoprosencephaly","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"26.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"237.5","Leydig cells":"191.0","Peritubular cells":"444.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"6.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"T-cells":"6.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NTERA-2":"29.6","WM-115":"71.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013717","HPA075072"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB013717":null,"HPA075072":"AB_2686733"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.0","Tissue RNA - adrenal gland [nTPM]":"3.5","Tissue RNA - amygdala [nTPM]":"9.5","Tissue RNA - appendix [nTPM]":"4.0","Tissue RNA - basal ganglia [nTPM]":"11.6","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"2.8","Tissue RNA - cerebellum [nTPM]":"24.6","Tissue RNA - cerebral cortex [nTPM]":"5.6","Tissue RNA - cervix [nTPM]":"26.7","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"11.3","Tissue RNA - duodenum [nTPM]":"8.1","Tissue RNA - endometrium 1 [nTPM]":"15.6","Tissue RNA - epididymis [nTPM]":"2.7","Tissue RNA - esophagus [nTPM]":"2.9","Tissue RNA - fallopian tube [nTPM]":"7.1","Tissue RNA - gallbladder [nTPM]":"8.1","Tissue RNA - heart muscle [nTPM]":"2.9","Tissue RNA - hippocampal formation [nTPM]":"4.7","Tissue RNA - hypothalamus [nTPM]":"17.8","Tissue RNA - kidney [nTPM]":"4.6","Tissue RNA - liver [nTPM]":"2.2","Tissue RNA - lung [nTPM]":"5.5","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"16.0","Tissue RNA - midbrain [nTPM]":"12.7","Tissue RNA - ovary [nTPM]":"5.0","Tissue RNA - pancreas [nTPM]":"6.4","Tissue RNA - parathyroid gland [nTPM]":"2.5","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"3.8","Tissue RNA - pons [nTPM]":"8.0","Tissue RNA - prostate [nTPM]":"6.8","Tissue RNA - rectum [nTPM]":"12.3","Tissue RNA - retina [nTPM]":"8.3","Tissue RNA - salivary gland [nTPM]":"7.5","Tissue RNA - seminal vesicle [nTPM]":"4.0","Tissue RNA - skeletal muscle [nTPM]":"3.0","Tissue RNA - skin 1 [nTPM]":"3.2","Tissue RNA - small intestine [nTPM]":"11.6","Tissue RNA - smooth muscle [nTPM]":"2.4","Tissue RNA - spinal cord [nTPM]":"7.0","Tissue RNA - spleen [nTPM]":"3.3","Tissue RNA - stomach 1 [nTPM]":"12.5","Tissue RNA - testis [nTPM]":"14.5","Tissue RNA - thalamus [nTPM]":"24.0","Tissue RNA - thymus [nTPM]":"2.1","Tissue RNA - thyroid gland [nTPM]":"4.7","Tissue RNA - tongue [nTPM]":"4.8","Tissue RNA - tonsil [nTPM]":"3.0","Tissue RNA - urinary bladder [nTPM]":"7.2","Tissue RNA - vagina [nTPM]":"2.9","Tissue RNA - white matter [nTPM]":"4.5","Cell RNA - A-431 [nTPM]":"10.1","Cell RNA - A549 [nTPM]":"4.7","Cell RNA - AF22 [nTPM]":"20.3","Cell RNA - AN3-CA [nTPM]":"12.9","Cell RNA - ASC diff [nTPM]":"3.0","Cell RNA - ASC TERT1 [nTPM]":"5.0","Cell RNA - BEWO [nTPM]":"11.4","Cell RNA - BJ [nTPM]":"1.9","Cell RNA - BJ hTERT+ [nTPM]":"1.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.4","Cell RNA - CACO-2 [nTPM]":"4.9","Cell RNA - CAPAN-2 [nTPM]":"4.8","Cell RNA - Daudi [nTPM]":"8.0","Cell RNA - EFO-21 [nTPM]":"3.3","Cell RNA - fHDF\/TERT166 [nTPM]":"3.8","Cell RNA - GAMG [nTPM]":"4.4","Cell RNA - HaCaT [nTPM]":"22.3","Cell RNA - HAP1 [nTPM]":"11.7","Cell RNA - HBEC3-KT [nTPM]":"1.6","Cell RNA - HBF TERT88 [nTPM]":"1.4","Cell RNA - HDLM-2 [nTPM]":"7.9","Cell RNA - HEK 293 [nTPM]":"7.8","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"4.8","Cell RNA - Hep G2 [nTPM]":"2.3","Cell RNA - HHSteC [nTPM]":"2.7","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"4.2","Cell RNA - HSkMC [nTPM]":"4.7","Cell RNA - hTCEpi [nTPM]":"2.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.2","Cell RNA - hTERT-HME1 [nTPM]":"1.4","Cell RNA - hTERT-RPE1 [nTPM]":"4.3","Cell RNA - HUVEC TERT2 [nTPM]":"4.2","Cell RNA - JURKAT [nTPM]":"3.5","Cell RNA - K-562 [nTPM]":"7.3","Cell RNA - Karpas-707 [nTPM]":"9.1","Cell RNA - LHCN-M2 [nTPM]":"1.0","Cell RNA - MCF7 [nTPM]":"1.9","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"3.2","Cell RNA - NTERA-2 [nTPM]":"29.6","Cell RNA - OE19 [nTPM]":"7.2","Cell RNA - PC-3 [nTPM]":"1.8","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"15.5","Cell RNA - RPMI-8226 [nTPM]":"4.2","Cell RNA - RPTEC TERT1 [nTPM]":"1.6","Cell RNA - RT4 [nTPM]":"1.5","Cell RNA - SCLC-21H [nTPM]":"13.8","Cell RNA - SH-SY5Y [nTPM]":"7.0","Cell RNA - SiHa [nTPM]":"7.1","Cell RNA - SK-BR-3 [nTPM]":"6.8","Cell RNA - SK-MEL-30 [nTPM]":"2.9","Cell RNA - SuSa [nTPM]":"18.8","Cell RNA - T-47d [nTPM]":"1.8","Cell RNA - THP-1 [nTPM]":"2.1","Cell RNA - TIME [nTPM]":"1.1","Cell RNA - U-138 MG [nTPM]":"2.6","Cell RNA - U-2 OS [nTPM]":"12.9","Cell RNA - U-2197 [nTPM]":"13.6","Cell RNA - U-251 MG [nTPM]":"1.5","Cell RNA - U-266\/70 [nTPM]":"18.0","Cell RNA - U-266\/84 [nTPM]":"16.8","Cell RNA - U-698 [nTPM]":"5.3","Cell RNA - U-87 MG [nTPM]":"3.8","Cell RNA - U-937 [nTPM]":"3.9","Cell RNA - WM-115 [nTPM]":"71.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"6.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"3.3","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"2.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"9.5","Brain RNA - basal ganglia [nTPM]":"11.6","Brain RNA - cerebellum [nTPM]":"24.6","Brain RNA - cerebral cortex [nTPM]":"5.6","Brain RNA - hippocampal formation [nTPM]":"4.7","Brain RNA - hypothalamus [nTPM]":"17.8","Brain RNA - medulla oblongata [nTPM]":"16.0","Brain RNA - midbrain [nTPM]":"12.7","Brain RNA - pons [nTPM]":"8.0","Brain RNA - spinal cord [nTPM]":"7.0","Brain RNA - thalamus [nTPM]":"24.0","Brain RNA - white matter [nTPM]":"4.5","Single Cell Type RNA - Adipocytes [nTPM]":"6.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.4","Single Cell Type RNA - Astrocytes [nTPM]":"49.0","Single Cell Type RNA - B-cells [nTPM]":"3.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"20.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"2.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - dendritic cells [nTPM]":"11.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.5","Single Cell Type RNA - Early spermatids [nTPM]":"88.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"89.8","Single Cell Type RNA - Endothelial cells [nTPM]":"5.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.7","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.9","Single Cell Type RNA - Fibroblasts [nTPM]":"27.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"2.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"2.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.8","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.9","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"237.5","Single Cell Type RNA - Leydig cells [nTPM]":"191.0","Single Cell Type RNA - Macrophages [nTPM]":"1.4","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.8","Single Cell Type RNA - Muller glia cells [nTPM]":"55.6","Single Cell Type RNA - NK-cells [nTPM]":"54.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"39.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.4","Single Cell Type RNA - Paneth cells [nTPM]":"3.1","Single Cell Type RNA - Peritubular cells [nTPM]":"444.5","Single Cell Type RNA - Plasma cells [nTPM]":"3.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.4","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.4","Single Cell Type RNA - Spermatocytes [nTPM]":"4.4","Single Cell Type RNA - Spermatogonia [nTPM]":"35.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"6.5","Single Cell Type RNA - Theca cells [nTPM]":"71.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.7","Single Cell Type RNA - Urothelial cells [nTPM]":"1.4"},{"Gene":"PTEN","Gene synonym":["BZS","MHAM","MMAC1","PTEN1","TEP1"],"Ensembl":"ENSG00000171862","Gene description":"Phosphatase and tensin homolog","Uniprot":["P60484"],"Chromosome":"10","Position":"87863625-87971930","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Lipid metabolism","Neurogenesis"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Autism spectrum disorder","Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"60.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004076","HPA031335"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004076":"AB_390810","HPA031335":"AB_2797221"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.35e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Tissue RNA - adipose tissue [nTPM]":"64.0","Tissue RNA - adrenal gland [nTPM]":"25.4","Tissue RNA - amygdala [nTPM]":"17.8","Tissue RNA - appendix [nTPM]":"18.6","Tissue RNA - basal ganglia [nTPM]":"19.3","Tissue RNA - bone marrow [nTPM]":"12.9","Tissue RNA - breast [nTPM]":"47.6","Tissue RNA - cerebellum [nTPM]":"34.5","Tissue RNA - cerebral cortex [nTPM]":"23.4","Tissue RNA - cervix [nTPM]":"54.8","Tissue RNA - choroid plexus [nTPM]":"15.6","Tissue RNA - colon [nTPM]":"28.1","Tissue RNA - duodenum [nTPM]":"12.9","Tissue RNA - endometrium 1 [nTPM]":"27.4","Tissue RNA - epididymis [nTPM]":"18.6","Tissue RNA - esophagus [nTPM]":"28.3","Tissue RNA - fallopian tube [nTPM]":"35.2","Tissue RNA - gallbladder [nTPM]":"15.6","Tissue RNA - heart muscle [nTPM]":"29.7","Tissue RNA - hippocampal formation [nTPM]":"20.4","Tissue RNA - hypothalamus [nTPM]":"18.4","Tissue RNA - kidney [nTPM]":"22.6","Tissue RNA - liver [nTPM]":"39.2","Tissue RNA - lung [nTPM]":"39.5","Tissue RNA - lymph node [nTPM]":"21.4","Tissue RNA - medulla oblongata [nTPM]":"16.6","Tissue RNA - midbrain [nTPM]":"17.8","Tissue RNA - ovary [nTPM]":"28.0","Tissue RNA - pancreas [nTPM]":"33.2","Tissue RNA - parathyroid gland [nTPM]":"11.9","Tissue RNA - pituitary gland [nTPM]":"17.3","Tissue RNA - placenta [nTPM]":"30.5","Tissue RNA - pons [nTPM]":"16.4","Tissue RNA - prostate [nTPM]":"26.3","Tissue RNA - rectum [nTPM]":"14.6","Tissue RNA - retina [nTPM]":"30.0","Tissue RNA - salivary gland [nTPM]":"19.6","Tissue RNA - seminal vesicle [nTPM]":"16.5","Tissue RNA - skeletal muscle [nTPM]":"23.7","Tissue RNA - skin 1 [nTPM]":"25.9","Tissue RNA - small intestine [nTPM]":"24.5","Tissue RNA - smooth muscle [nTPM]":"22.2","Tissue RNA - spinal cord [nTPM]":"14.5","Tissue RNA - spleen [nTPM]":"40.0","Tissue RNA - stomach 1 [nTPM]":"25.6","Tissue RNA - testis [nTPM]":"28.2","Tissue RNA - thalamus [nTPM]":"19.7","Tissue RNA - thymus [nTPM]":"31.8","Tissue RNA - thyroid gland [nTPM]":"26.1","Tissue RNA - tongue [nTPM]":"14.0","Tissue RNA - tonsil [nTPM]":"16.5","Tissue RNA - urinary bladder [nTPM]":"28.1","Tissue RNA - vagina [nTPM]":"38.4","Tissue RNA - white matter [nTPM]":"17.6","Cell RNA - A-431 [nTPM]":"23.5","Cell RNA - A549 [nTPM]":"10.8","Cell RNA - AF22 [nTPM]":"12.3","Cell RNA - AN3-CA [nTPM]":"11.2","Cell RNA - ASC diff [nTPM]":"28.5","Cell RNA - ASC TERT1 [nTPM]":"19.7","Cell RNA - BEWO [nTPM]":"10.9","Cell RNA - BJ [nTPM]":"12.5","Cell RNA - BJ hTERT+ [nTPM]":"28.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.4","Cell RNA - CACO-2 [nTPM]":"10.9","Cell RNA - CAPAN-2 [nTPM]":"28.0","Cell RNA - Daudi [nTPM]":"28.1","Cell RNA - EFO-21 [nTPM]":"8.0","Cell RNA - fHDF\/TERT166 [nTPM]":"20.9","Cell RNA - GAMG [nTPM]":"8.3","Cell RNA - HaCaT [nTPM]":"14.1","Cell RNA - HAP1 [nTPM]":"16.6","Cell RNA - HBEC3-KT [nTPM]":"14.3","Cell RNA - HBF TERT88 [nTPM]":"22.8","Cell RNA - HDLM-2 [nTPM]":"14.1","Cell RNA - HEK 293 [nTPM]":"4.7","Cell RNA - HEL [nTPM]":"9.3","Cell RNA - HeLa [nTPM]":"28.5","Cell RNA - Hep G2 [nTPM]":"13.8","Cell RNA - HHSteC [nTPM]":"30.1","Cell RNA - HL-60 [nTPM]":"31.9","Cell RNA - HMC-1 [nTPM]":"15.3","Cell RNA - HSkMC [nTPM]":"13.5","Cell RNA - hTCEpi [nTPM]":"38.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.0","Cell RNA - hTERT-HME1 [nTPM]":"23.7","Cell RNA - hTERT-RPE1 [nTPM]":"60.3","Cell RNA - HUVEC TERT2 [nTPM]":"20.8","Cell RNA - JURKAT [nTPM]":"17.7","Cell RNA - K-562 [nTPM]":"7.0","Cell RNA - Karpas-707 [nTPM]":"72.6","Cell RNA - LHCN-M2 [nTPM]":"13.5","Cell RNA - MCF7 [nTPM]":"18.1","Cell RNA - MOLT-4 [nTPM]":"17.8","Cell RNA - NB-4 [nTPM]":"56.3","Cell RNA - NTERA-2 [nTPM]":"4.6","Cell RNA - OE19 [nTPM]":"19.9","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"27.6","Cell RNA - RH-30 [nTPM]":"6.4","Cell RNA - RPMI-8226 [nTPM]":"20.8","Cell RNA - RPTEC TERT1 [nTPM]":"22.9","Cell RNA - RT4 [nTPM]":"13.4","Cell RNA - SCLC-21H [nTPM]":"4.5","Cell RNA - SH-SY5Y [nTPM]":"19.9","Cell RNA - SiHa [nTPM]":"16.6","Cell RNA - SK-BR-3 [nTPM]":"7.9","Cell RNA - SK-MEL-30 [nTPM]":"23.0","Cell RNA - SuSa [nTPM]":"9.7","Cell RNA - T-47d [nTPM]":"21.9","Cell RNA - THP-1 [nTPM]":"45.2","Cell RNA - TIME [nTPM]":"17.9","Cell RNA - U-138 MG [nTPM]":"44.6","Cell RNA - U-2 OS [nTPM]":"10.8","Cell RNA - U-2197 [nTPM]":"18.3","Cell RNA - U-251 MG [nTPM]":"10.1","Cell RNA - U-266\/70 [nTPM]":"23.9","Cell RNA - U-266\/84 [nTPM]":"32.9","Cell RNA - U-698 [nTPM]":"30.7","Cell RNA - U-87 MG [nTPM]":"14.6","Cell RNA - U-937 [nTPM]":"29.2","Cell RNA - WM-115 [nTPM]":"2.9","Blood RNA - basophil [nTPM]":"21.3","Blood RNA - classical monocyte [nTPM]":"14.2","Blood RNA - eosinophil [nTPM]":"25.8","Blood RNA - gdT-cell [nTPM]":"6.8","Blood RNA - intermediate monocyte [nTPM]":"21.8","Blood RNA - MAIT T-cell [nTPM]":"7.2","Blood RNA - memory B-cell [nTPM]":"7.9","Blood RNA - memory CD4 T-cell [nTPM]":"7.2","Blood RNA - memory CD8 T-cell [nTPM]":"6.6","Blood RNA - myeloid DC [nTPM]":"10.3","Blood RNA - naive B-cell [nTPM]":"6.8","Blood RNA - naive CD4 T-cell [nTPM]":"8.3","Blood RNA - naive CD8 T-cell [nTPM]":"8.3","Blood RNA - neutrophil [nTPM]":"60.5","Blood RNA - NK-cell [nTPM]":"8.9","Blood RNA - non-classical monocyte [nTPM]":"15.6","Blood RNA - plasmacytoid DC [nTPM]":"8.2","Blood RNA - T-reg [nTPM]":"7.0","Blood RNA - total PBMC [nTPM]":"4.5","Brain RNA - amygdala [nTPM]":"17.8","Brain RNA - basal ganglia [nTPM]":"19.3","Brain RNA - cerebellum [nTPM]":"34.5","Brain RNA - cerebral cortex [nTPM]":"23.4","Brain RNA - hippocampal formation [nTPM]":"20.4","Brain RNA - hypothalamus [nTPM]":"18.4","Brain RNA - medulla oblongata [nTPM]":"16.6","Brain RNA - midbrain [nTPM]":"17.8","Brain RNA - pons [nTPM]":"16.4","Brain RNA - spinal cord [nTPM]":"14.5","Brain RNA - thalamus [nTPM]":"19.7","Brain RNA - white matter [nTPM]":"17.6","Single Cell Type RNA - Adipocytes [nTPM]":"67.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"63.3","Single Cell Type RNA - Astrocytes [nTPM]":"83.6","Single Cell Type RNA - B-cells [nTPM]":"48.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"56.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"57.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"31.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"47.3","Single Cell Type RNA - Bipolar cells [nTPM]":"113.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"49.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"41.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"46.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"57.2","Single Cell Type RNA - Club cells [nTPM]":"31.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.8","Single Cell Type RNA - dendritic cells [nTPM]":"64.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"57.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"24.7","Single Cell Type RNA - Early spermatids [nTPM]":"70.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"40.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"114.5","Single Cell Type RNA - Endothelial cells [nTPM]":"56.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"31.2","Single Cell Type RNA - Erythroid cells [nTPM]":"52.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"141.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"62.2","Single Cell Type RNA - Fibroblasts [nTPM]":"79.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"33.6","Single Cell Type RNA - granulocytes [nTPM]":"25.4","Single Cell Type RNA - Granulosa cells [nTPM]":"39.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"53.9","Single Cell Type RNA - Hepatocytes [nTPM]":"64.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.0","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"132.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"44.7","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"206.1","Single Cell Type RNA - Langerhans cells [nTPM]":"97.2","Single Cell Type RNA - Late spermatids [nTPM]":"92.1","Single Cell Type RNA - Leydig cells [nTPM]":"56.8","Single Cell Type RNA - Macrophages [nTPM]":"105.2","Single Cell Type RNA - Melanocytes [nTPM]":"62.2","Single Cell Type RNA - Microglial cells [nTPM]":"196.8","Single Cell Type RNA - monocytes [nTPM]":"101.5","Single Cell Type RNA - Muller glia cells [nTPM]":"61.6","Single Cell Type RNA - NK-cells [nTPM]":"44.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"139.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"95.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"30.6","Single Cell Type RNA - Paneth cells [nTPM]":"39.7","Single Cell Type RNA - Peritubular cells [nTPM]":"54.5","Single Cell Type RNA - Plasma cells [nTPM]":"39.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"45.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"50.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"38.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"31.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"61.2","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"66.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"170.7","Single Cell Type RNA - Spermatocytes [nTPM]":"33.5","Single Cell Type RNA - Spermatogonia [nTPM]":"25.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"45.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"60.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"57.3","Single Cell Type RNA - T-cells [nTPM]":"46.3","Single Cell Type RNA - Theca cells [nTPM]":"44.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"46.1","Single Cell Type RNA - Urothelial cells [nTPM]":"64.0"},{"Gene":"SHH","Gene synonym":["HHG1","HLP3","HPE3","MCOPCB5","SMMCI","TPT","TPTPS"],"Ensembl":"ENSG00000164690","Gene description":"Sonic hedgehog signaling molecule","Uniprot":["Q15465"],"Chromosome":"7","Position":"155799980-155812463","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Developmental protein","Hydrolase","Protease"],"Disease involvement":["Disease variant","Holoprosencephaly","Microphthalmia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"13.6","stomach 1":"10.5","urinary bladder":"16.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"8.3","Cholangiocytes":"18.6","Collecting duct cells":"9.2","Gastric mucus-secreting cells":"9.7","Hepatocytes":"20.1","Intestinal goblet cells":"8.6","Pancreatic endocrine cells":"11.7","Urothelial cells":"8.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"8.9","GAMG":"39.8","OE19":"10.2","RT4":"25.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5500000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.62e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"8.7","Tissue RNA - amygdala [nTPM]":"1.3","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"1.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"1.6","Tissue RNA - cerebral cortex [nTPM]":"1.2","Tissue RNA - cervix [nTPM]":"4.4","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"1.3","Tissue RNA - duodenum [nTPM]":"1.4","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"3.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"3.8","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"6.2","Tissue RNA - kidney [nTPM]":"3.3","Tissue RNA - liver [nTPM]":"13.6","Tissue RNA - lung [nTPM]":"1.7","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"3.3","Tissue RNA - midbrain [nTPM]":"1.6","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"4.6","Tissue RNA - prostate [nTPM]":"1.2","Tissue RNA - rectum [nTPM]":"1.0","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"1.2","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"1.4","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"10.5","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"2.6","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"16.2","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"1.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"1.3","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"5.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"8.9","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"39.8","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"3.9","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"10.2","Cell RNA - PC-3 [nTPM]":"4.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"2.0","Cell RNA - RT4 [nTPM]":"25.7","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"1.1","Cell RNA - TIME [nTPM]":"2.4","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.3","Brain RNA - basal ganglia [nTPM]":"1.2","Brain RNA - cerebellum [nTPM]":"1.6","Brain RNA - cerebral cortex [nTPM]":"1.2","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"6.2","Brain RNA - medulla oblongata [nTPM]":"3.3","Brain RNA - midbrain [nTPM]":"1.6","Brain RNA - pons [nTPM]":"4.6","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"2.6","Brain RNA - white matter [nTPM]":"1.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.2","Single Cell Type RNA - Early spermatids [nTPM]":"4.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"20.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"2.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.0","Single Cell Type RNA - Urothelial cells [nTPM]":"8.3"},{"Gene":"SMO","Gene synonym":["FZD11","SMOH"],"Ensembl":"ENSG00000128602","Gene description":"Smoothened, frizzled class receptor","Uniprot":["Q99835"],"Chromosome":"7","Position":"129188633-129213545","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"27.4","Granulosa cells":"13.0","Leydig cells":"20.8","Muller glia cells":"16.6","Peritubular cells":"21.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"45.3","AN3-CA":"84.9","NTERA-2":"64.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011446"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 23: AN3-CA - Transcription regulation","Single cell expression cluster":"Cluster 36: Stromal cells - Cell proliferation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB011446":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.2","Tissue RNA - adrenal gland [nTPM]":"6.0","Tissue RNA - amygdala [nTPM]":"9.4","Tissue RNA - appendix [nTPM]":"2.6","Tissue RNA - basal ganglia [nTPM]":"10.8","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"5.5","Tissue RNA - cerebellum [nTPM]":"9.9","Tissue RNA - cerebral cortex [nTPM]":"9.6","Tissue RNA - cervix [nTPM]":"27.4","Tissue RNA - choroid plexus [nTPM]":"18.4","Tissue RNA - colon [nTPM]":"9.6","Tissue RNA - duodenum [nTPM]":"2.5","Tissue RNA - endometrium 1 [nTPM]":"19.2","Tissue RNA - epididymis [nTPM]":"18.6","Tissue RNA - esophagus [nTPM]":"12.0","Tissue RNA - fallopian tube [nTPM]":"14.5","Tissue RNA - gallbladder [nTPM]":"8.4","Tissue RNA - heart muscle [nTPM]":"8.0","Tissue RNA - hippocampal formation [nTPM]":"8.9","Tissue RNA - hypothalamus [nTPM]":"10.0","Tissue RNA - kidney [nTPM]":"19.0","Tissue RNA - liver [nTPM]":"23.9","Tissue RNA - lung [nTPM]":"3.6","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"12.4","Tissue RNA - midbrain [nTPM]":"12.4","Tissue RNA - ovary [nTPM]":"28.3","Tissue RNA - pancreas [nTPM]":"6.3","Tissue RNA - parathyroid gland [nTPM]":"16.1","Tissue RNA - pituitary gland [nTPM]":"19.2","Tissue RNA - placenta [nTPM]":"2.6","Tissue RNA - pons [nTPM]":"9.9","Tissue RNA - prostate [nTPM]":"20.0","Tissue RNA - rectum [nTPM]":"2.1","Tissue RNA - retina [nTPM]":"2.0","Tissue RNA - salivary gland [nTPM]":"11.5","Tissue RNA - seminal vesicle [nTPM]":"12.3","Tissue RNA - skeletal muscle [nTPM]":"3.7","Tissue RNA - skin 1 [nTPM]":"17.1","Tissue RNA - small intestine [nTPM]":"5.7","Tissue RNA - smooth muscle [nTPM]":"8.1","Tissue RNA - spinal cord [nTPM]":"11.8","Tissue RNA - spleen [nTPM]":"2.8","Tissue RNA - stomach 1 [nTPM]":"6.3","Tissue RNA - testis [nTPM]":"5.6","Tissue RNA - thalamus [nTPM]":"11.4","Tissue RNA - thymus [nTPM]":"4.4","Tissue RNA - thyroid gland [nTPM]":"9.1","Tissue RNA - tongue [nTPM]":"3.7","Tissue RNA - tonsil [nTPM]":"2.0","Tissue RNA - urinary bladder [nTPM]":"9.0","Tissue RNA - vagina [nTPM]":"16.7","Tissue RNA - white matter [nTPM]":"9.7","Cell RNA - A-431 [nTPM]":"1.6","Cell RNA - A549 [nTPM]":"18.2","Cell RNA - AF22 [nTPM]":"45.3","Cell RNA - AN3-CA [nTPM]":"84.9","Cell RNA - ASC diff [nTPM]":"1.1","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"14.3","Cell RNA - BJ [nTPM]":"5.2","Cell RNA - BJ hTERT+ [nTPM]":"6.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.8","Cell RNA - CACO-2 [nTPM]":"13.8","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"13.9","Cell RNA - fHDF\/TERT166 [nTPM]":"10.4","Cell RNA - GAMG [nTPM]":"22.8","Cell RNA - HaCaT [nTPM]":"28.3","Cell RNA - HAP1 [nTPM]":"27.4","Cell RNA - HBEC3-KT [nTPM]":"1.5","Cell RNA - HBF TERT88 [nTPM]":"3.9","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"23.0","Cell RNA - HEL [nTPM]":"9.4","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"22.5","Cell RNA - HHSteC [nTPM]":"5.5","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"16.2","Cell RNA - hTCEpi [nTPM]":"11.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.3","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"19.9","Cell RNA - HUVEC TERT2 [nTPM]":"5.8","Cell RNA - JURKAT [nTPM]":"24.9","Cell RNA - K-562 [nTPM]":"1.5","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"3.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"24.4","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"64.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"5.3","Cell RNA - REH [nTPM]":"35.1","Cell RNA - RH-30 [nTPM]":"19.7","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"5.2","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.3","Cell RNA - SH-SY5Y [nTPM]":"30.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"12.3","Cell RNA - SuSa [nTPM]":"16.8","Cell RNA - T-47d [nTPM]":"11.1","Cell RNA - THP-1 [nTPM]":"5.8","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.7","Cell RNA - U-2 OS [nTPM]":"14.1","Cell RNA - U-2197 [nTPM]":"17.6","Cell RNA - U-251 MG [nTPM]":"10.1","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"16.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"9.4","Brain RNA - basal ganglia [nTPM]":"10.8","Brain RNA - cerebellum [nTPM]":"9.9","Brain RNA - cerebral cortex [nTPM]":"9.6","Brain RNA - hippocampal formation [nTPM]":"8.9","Brain RNA - hypothalamus [nTPM]":"10.0","Brain RNA - medulla oblongata [nTPM]":"12.4","Brain RNA - midbrain [nTPM]":"12.4","Brain RNA - pons [nTPM]":"9.9","Brain RNA - spinal cord [nTPM]":"11.8","Brain RNA - thalamus [nTPM]":"11.4","Brain RNA - white matter [nTPM]":"9.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"27.4","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"3.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"7.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"13.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"8.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"20.8","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"16.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"21.8","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"2.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"6.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"TP53","Gene synonym":["LFS1","p53"],"Ensembl":"ENSG00000141510","Gene description":"Tumor protein p53","Uniprot":["P04637"],"Chromosome":"17","Position":"7661779-7687538","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transcription factors","Transporters"],"Biological process":["Apoptosis","Biological rhythms","Cell cycle","Host-virus interaction","Necrosis","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant","Li-Fraumeni syndrome","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002973","CAB039238","CAB039239","HPA051244","HPA063532","CAB072876","CAB079965"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 14: REH - Unknown function","Single cell expression cluster":"Cluster 32: Non-specific - Translation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Mitochondria","Cytosol"],"Antibody RRID":{"CAB002973":"AB_2206626","CAB039238":null,"CAB039239":null,"CAB072876":"AB_2665731","CAB079965":null,"HPA051244":"AB_2681403","HPA063532":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.35e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.01e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Tissue RNA - adipose tissue [nTPM]":"19.3","Tissue RNA - adrenal gland [nTPM]":"13.8","Tissue RNA - amygdala [nTPM]":"10.4","Tissue RNA - appendix [nTPM]":"27.1","Tissue RNA - basal ganglia [nTPM]":"12.6","Tissue RNA - bone marrow [nTPM]":"19.6","Tissue RNA - breast [nTPM]":"22.5","Tissue RNA - cerebellum [nTPM]":"10.4","Tissue RNA - cerebral cortex [nTPM]":"16.5","Tissue RNA - cervix [nTPM]":"19.9","Tissue RNA - choroid plexus [nTPM]":"10.3","Tissue RNA - colon [nTPM]":"29.0","Tissue RNA - duodenum [nTPM]":"18.9","Tissue RNA - endometrium 1 [nTPM]":"24.5","Tissue RNA - epididymis [nTPM]":"12.8","Tissue RNA - esophagus [nTPM]":"28.8","Tissue RNA - fallopian tube [nTPM]":"31.3","Tissue RNA - gallbladder [nTPM]":"13.2","Tissue RNA - heart muscle [nTPM]":"11.1","Tissue RNA - hippocampal formation [nTPM]":"10.1","Tissue RNA - hypothalamus [nTPM]":"11.4","Tissue RNA - kidney [nTPM]":"14.9","Tissue RNA - liver [nTPM]":"16.5","Tissue RNA - lung [nTPM]":"15.1","Tissue RNA - lymph node [nTPM]":"34.6","Tissue RNA - medulla oblongata [nTPM]":"18.7","Tissue RNA - midbrain [nTPM]":"13.6","Tissue RNA - ovary [nTPM]":"27.3","Tissue RNA - pancreas [nTPM]":"18.3","Tissue RNA - parathyroid gland [nTPM]":"9.4","Tissue RNA - pituitary gland [nTPM]":"7.3","Tissue RNA - placenta [nTPM]":"23.5","Tissue RNA - pons [nTPM]":"12.5","Tissue RNA - prostate [nTPM]":"17.7","Tissue RNA - rectum [nTPM]":"27.5","Tissue RNA - retina [nTPM]":"4.1","Tissue RNA - salivary gland [nTPM]":"18.9","Tissue RNA - seminal vesicle [nTPM]":"15.3","Tissue RNA - skeletal muscle [nTPM]":"12.3","Tissue RNA - skin 1 [nTPM]":"37.4","Tissue RNA - small intestine [nTPM]":"20.4","Tissue RNA - smooth muscle [nTPM]":"24.6","Tissue RNA - spinal cord [nTPM]":"12.6","Tissue RNA - spleen [nTPM]":"31.1","Tissue RNA - stomach 1 [nTPM]":"22.6","Tissue RNA - testis [nTPM]":"10.4","Tissue RNA - thalamus [nTPM]":"12.3","Tissue RNA - thymus [nTPM]":"47.2","Tissue RNA - thyroid gland [nTPM]":"17.4","Tissue RNA - tongue [nTPM]":"6.1","Tissue RNA - tonsil [nTPM]":"45.4","Tissue RNA - urinary bladder [nTPM]":"20.8","Tissue RNA - vagina [nTPM]":"19.9","Tissue RNA - white matter [nTPM]":"13.3","Cell RNA - A-431 [nTPM]":"81.5","Cell RNA - A549 [nTPM]":"145.3","Cell RNA - AF22 [nTPM]":"81.1","Cell RNA - AN3-CA [nTPM]":"57.3","Cell RNA - ASC diff [nTPM]":"37.3","Cell RNA - ASC TERT1 [nTPM]":"43.9","Cell RNA - BEWO [nTPM]":"82.8","Cell RNA - BJ [nTPM]":"28.4","Cell RNA - BJ hTERT+ [nTPM]":"66.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"78.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"100.2","Cell RNA - CACO-2 [nTPM]":"4.2","Cell RNA - CAPAN-2 [nTPM]":"40.6","Cell RNA - Daudi [nTPM]":"190.5","Cell RNA - EFO-21 [nTPM]":"126.9","Cell RNA - fHDF\/TERT166 [nTPM]":"58.7","Cell RNA - GAMG [nTPM]":"77.6","Cell RNA - HaCaT [nTPM]":"174.9","Cell RNA - HAP1 [nTPM]":"119.7","Cell RNA - HBEC3-KT [nTPM]":"80.4","Cell RNA - HBF TERT88 [nTPM]":"72.8","Cell RNA - HDLM-2 [nTPM]":"42.7","Cell RNA - HEK 293 [nTPM]":"76.5","Cell RNA - HEL [nTPM]":"77.6","Cell RNA - HeLa [nTPM]":"76.8","Cell RNA - Hep G2 [nTPM]":"70.9","Cell RNA - HHSteC [nTPM]":"111.5","Cell RNA - HL-60 [nTPM]":"1.6","Cell RNA - HMC-1 [nTPM]":"37.0","Cell RNA - HSkMC [nTPM]":"55.7","Cell RNA - hTCEpi [nTPM]":"93.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"38.9","Cell RNA - hTERT-HME1 [nTPM]":"106.5","Cell RNA - hTERT-RPE1 [nTPM]":"45.6","Cell RNA - HUVEC TERT2 [nTPM]":"79.4","Cell RNA - JURKAT [nTPM]":"24.7","Cell RNA - K-562 [nTPM]":"3.8","Cell RNA - Karpas-707 [nTPM]":"6.9","Cell RNA - LHCN-M2 [nTPM]":"41.5","Cell RNA - MCF7 [nTPM]":"145.1","Cell RNA - MOLT-4 [nTPM]":"130.0","Cell RNA - NB-4 [nTPM]":"96.3","Cell RNA - NTERA-2 [nTPM]":"80.2","Cell RNA - OE19 [nTPM]":"10.4","Cell RNA - PC-3 [nTPM]":"2.4","Cell RNA - REH [nTPM]":"252.2","Cell RNA - RH-30 [nTPM]":"56.1","Cell RNA - RPMI-8226 [nTPM]":"66.2","Cell RNA - RPTEC TERT1 [nTPM]":"59.4","Cell RNA - RT4 [nTPM]":"87.3","Cell RNA - SCLC-21H [nTPM]":"46.0","Cell RNA - SH-SY5Y [nTPM]":"80.5","Cell RNA - SiHa [nTPM]":"94.1","Cell RNA - SK-BR-3 [nTPM]":"62.6","Cell RNA - SK-MEL-30 [nTPM]":"24.3","Cell RNA - SuSa [nTPM]":"39.4","Cell RNA - T-47d [nTPM]":"109.2","Cell RNA - THP-1 [nTPM]":"7.4","Cell RNA - TIME [nTPM]":"100.7","Cell RNA - U-138 MG [nTPM]":"91.6","Cell RNA - U-2 OS [nTPM]":"30.2","Cell RNA - U-2197 [nTPM]":"1.0","Cell RNA - U-251 MG [nTPM]":"48.3","Cell RNA - U-266\/70 [nTPM]":"47.6","Cell RNA - U-266\/84 [nTPM]":"37.9","Cell RNA - U-698 [nTPM]":"82.5","Cell RNA - U-87 MG [nTPM]":"23.6","Cell RNA - U-937 [nTPM]":"9.7","Cell RNA - WM-115 [nTPM]":"80.1","Blood RNA - basophil [nTPM]":"1.2","Blood RNA - classical monocyte [nTPM]":"21.2","Blood RNA - eosinophil [nTPM]":"3.4","Blood RNA - gdT-cell [nTPM]":"13.0","Blood RNA - intermediate monocyte [nTPM]":"21.7","Blood RNA - MAIT T-cell [nTPM]":"15.9","Blood RNA - memory B-cell [nTPM]":"21.5","Blood RNA - memory CD4 T-cell [nTPM]":"13.3","Blood RNA - memory CD8 T-cell [nTPM]":"14.6","Blood RNA - myeloid DC [nTPM]":"30.3","Blood RNA - naive B-cell [nTPM]":"19.1","Blood RNA - naive CD4 T-cell [nTPM]":"13.7","Blood RNA - naive CD8 T-cell [nTPM]":"15.4","Blood RNA - neutrophil [nTPM]":"2.4","Blood RNA - NK-cell [nTPM]":"17.5","Blood RNA - non-classical monocyte [nTPM]":"19.3","Blood RNA - plasmacytoid DC [nTPM]":"27.3","Blood RNA - T-reg [nTPM]":"17.3","Blood RNA - total PBMC [nTPM]":"14.7","Brain RNA - amygdala [nTPM]":"10.4","Brain RNA - basal ganglia [nTPM]":"12.6","Brain RNA - cerebellum [nTPM]":"10.4","Brain RNA - cerebral cortex [nTPM]":"16.5","Brain RNA - hippocampal formation [nTPM]":"10.1","Brain RNA - hypothalamus [nTPM]":"11.4","Brain RNA - medulla oblongata [nTPM]":"18.7","Brain RNA - midbrain [nTPM]":"13.6","Brain RNA - pons [nTPM]":"12.5","Brain RNA - spinal cord [nTPM]":"12.6","Brain RNA - thalamus [nTPM]":"12.3","Brain RNA - white matter [nTPM]":"13.3","Single Cell Type RNA - Adipocytes [nTPM]":"21.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.8","Single Cell Type RNA - Astrocytes [nTPM]":"16.3","Single Cell Type RNA - B-cells [nTPM]":"26.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"28.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"24.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"2.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"36.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"15.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"36.9","Single Cell Type RNA - dendritic cells [nTPM]":"24.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"24.8","Single Cell Type RNA - Early spermatids [nTPM]":"12.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.0","Single Cell Type RNA - Endothelial cells [nTPM]":"24.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"30.7","Single Cell Type RNA - Erythroid cells [nTPM]":"21.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"39.6","Single Cell Type RNA - Fibroblasts [nTPM]":"17.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"31.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.1","Single Cell Type RNA - Hepatocytes [nTPM]":"18.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"43.0","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"27.8","Single Cell Type RNA - Langerhans cells [nTPM]":"20.1","Single Cell Type RNA - Late spermatids [nTPM]":"3.8","Single Cell Type RNA - Leydig cells [nTPM]":"23.0","Single Cell Type RNA - Macrophages [nTPM]":"19.3","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"31.9","Single Cell Type RNA - Muller glia cells [nTPM]":"4.9","Single Cell Type RNA - NK-cells [nTPM]":"25.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.8","Single Cell Type RNA - Paneth cells [nTPM]":"16.4","Single Cell Type RNA - Peritubular cells [nTPM]":"17.0","Single Cell Type RNA - Plasma cells [nTPM]":"7.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"4.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"32.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.4","Single Cell Type RNA - T-cells [nTPM]":"16.5","Single Cell Type RNA - Theca cells [nTPM]":"27.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"54.1","Single Cell Type RNA - Urothelial cells [nTPM]":"11.5"}]