Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"	"Tissue RNA - adipose tissue [nTPM]"	"Tissue RNA - adrenal gland [nTPM]"	"Tissue RNA - amygdala [nTPM]"	"Tissue RNA - appendix [nTPM]"	"Tissue RNA - basal ganglia [nTPM]"	"Tissue RNA - bone marrow [nTPM]"	"Tissue RNA - breast [nTPM]"	"Tissue RNA - cerebellum [nTPM]"	"Tissue RNA - cerebral cortex [nTPM]"	"Tissue RNA - cervix [nTPM]"	"Tissue RNA - choroid plexus [nTPM]"	"Tissue RNA - colon [nTPM]"	"Tissue RNA - duodenum [nTPM]"	"Tissue RNA - endometrium 1 [nTPM]"	"Tissue RNA - epididymis [nTPM]"	"Tissue RNA - esophagus [nTPM]"	"Tissue RNA - fallopian tube [nTPM]"	"Tissue RNA - gallbladder [nTPM]"	"Tissue RNA - heart muscle [nTPM]"	"Tissue RNA - hippocampal formation [nTPM]"	"Tissue RNA - hypothalamus [nTPM]"	"Tissue RNA - kidney [nTPM]"	"Tissue RNA - liver [nTPM]"	"Tissue RNA - lung [nTPM]"	"Tissue RNA - lymph node [nTPM]"	"Tissue RNA - medulla oblongata [nTPM]"	"Tissue RNA - midbrain [nTPM]"	"Tissue RNA - ovary [nTPM]"	"Tissue RNA - pancreas [nTPM]"	"Tissue RNA - parathyroid gland [nTPM]"	"Tissue RNA - pituitary gland [nTPM]"	"Tissue RNA - placenta [nTPM]"	"Tissue RNA - pons [nTPM]"	"Tissue RNA - prostate [nTPM]"	"Tissue RNA - rectum [nTPM]"	"Tissue RNA - retina [nTPM]"	"Tissue RNA - salivary gland [nTPM]"	"Tissue RNA - seminal vesicle [nTPM]"	"Tissue RNA - skeletal muscle [nTPM]"	"Tissue RNA - skin 1 [nTPM]"	"Tissue RNA - small intestine [nTPM]"	"Tissue RNA - smooth muscle [nTPM]"	"Tissue RNA - spinal cord [nTPM]"	"Tissue RNA - spleen [nTPM]"	"Tissue RNA - stomach 1 [nTPM]"	"Tissue RNA - testis [nTPM]"	"Tissue RNA - thalamus [nTPM]"	"Tissue RNA - thymus [nTPM]"	"Tissue RNA - thyroid gland [nTPM]"	"Tissue RNA - tongue [nTPM]"	"Tissue RNA - tonsil [nTPM]"	"Tissue RNA - urinary bladder [nTPM]"	"Tissue RNA - vagina [nTPM]"	"Tissue RNA - white matter [nTPM]"	"Cell RNA - A-431 [nTPM]"	"Cell RNA - A549 [nTPM]"	"Cell RNA - AF22 [nTPM]"	"Cell RNA - AN3-CA [nTPM]"	"Cell RNA - ASC diff [nTPM]"	"Cell RNA - ASC TERT1 [nTPM]"	"Cell RNA - BEWO [nTPM]"	"Cell RNA - BJ [nTPM]"	"Cell RNA - BJ hTERT+ [nTPM]"	"Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]"	"Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]"	"Cell RNA - CACO-2 [nTPM]"	"Cell RNA - CAPAN-2 [nTPM]"	"Cell RNA - Daudi [nTPM]"	"Cell RNA - EFO-21 [nTPM]"	"Cell RNA - fHDF/TERT166 [nTPM]"	"Cell RNA - GAMG [nTPM]"	"Cell RNA - HaCaT [nTPM]"	"Cell RNA - HAP1 [nTPM]"	"Cell RNA - HBEC3-KT [nTPM]"	"Cell RNA - HBF TERT88 [nTPM]"	"Cell RNA - HDLM-2 [nTPM]"	"Cell RNA - HEK 293 [nTPM]"	"Cell RNA - HEL [nTPM]"	"Cell RNA - HeLa [nTPM]"	"Cell RNA - Hep G2 [nTPM]"	"Cell RNA - HHSteC [nTPM]"	"Cell RNA - HL-60 [nTPM]"	"Cell RNA - HMC-1 [nTPM]"	"Cell RNA - HSkMC [nTPM]"	"Cell RNA - hTCEpi [nTPM]"	"Cell RNA - hTEC/SVTERT24-B [nTPM]"	"Cell RNA - hTERT-HME1 [nTPM]"	"Cell RNA - hTERT-RPE1 [nTPM]"	"Cell RNA - HUVEC TERT2 [nTPM]"	"Cell RNA - JURKAT [nTPM]"	"Cell RNA - K-562 [nTPM]"	"Cell RNA - Karpas-707 [nTPM]"	"Cell RNA - LHCN-M2 [nTPM]"	"Cell RNA - MCF7 [nTPM]"	"Cell RNA - MOLT-4 [nTPM]"	"Cell RNA - NB-4 [nTPM]"	"Cell RNA - NTERA-2 [nTPM]"	"Cell RNA - OE19 [nTPM]"	"Cell RNA - PC-3 [nTPM]"	"Cell RNA - REH [nTPM]"	"Cell RNA - RH-30 [nTPM]"	"Cell RNA - RPMI-8226 [nTPM]"	"Cell RNA - RPTEC TERT1 [nTPM]"	"Cell RNA - RT4 [nTPM]"	"Cell RNA - SCLC-21H [nTPM]"	"Cell RNA - SH-SY5Y [nTPM]"	"Cell RNA - SiHa [nTPM]"	"Cell RNA - SK-BR-3 [nTPM]"	"Cell RNA - SK-MEL-30 [nTPM]"	"Cell RNA - SuSa [nTPM]"	"Cell RNA - T-47d [nTPM]"	"Cell RNA - THP-1 [nTPM]"	"Cell RNA - TIME [nTPM]"	"Cell RNA - U-138 MG [nTPM]"	"Cell RNA - U-2 OS [nTPM]"	"Cell RNA - U-2197 [nTPM]"	"Cell RNA - U-251 MG [nTPM]"	"Cell RNA - U-266/70 [nTPM]"	"Cell RNA - U-266/84 [nTPM]"	"Cell RNA - U-698 [nTPM]"	"Cell RNA - U-87 MG [nTPM]"	"Cell RNA - U-937 [nTPM]"	"Cell RNA - WM-115 [nTPM]"	"Blood RNA - basophil [nTPM]"	"Blood RNA - classical monocyte [nTPM]"	"Blood RNA - eosinophil [nTPM]"	"Blood RNA - gdT-cell [nTPM]"	"Blood RNA - intermediate monocyte [nTPM]"	"Blood RNA - MAIT T-cell [nTPM]"	"Blood RNA - memory B-cell [nTPM]"	"Blood RNA - memory CD4 T-cell [nTPM]"	"Blood RNA - memory CD8 T-cell [nTPM]"	"Blood RNA - myeloid DC [nTPM]"	"Blood RNA - naive B-cell [nTPM]"	"Blood RNA - naive CD4 T-cell [nTPM]"	"Blood RNA - naive CD8 T-cell [nTPM]"	"Blood RNA - neutrophil [nTPM]"	"Blood RNA - NK-cell [nTPM]"	"Blood RNA - non-classical monocyte [nTPM]"	"Blood RNA - plasmacytoid DC [nTPM]"	"Blood RNA - T-reg [nTPM]"	"Blood RNA - total PBMC [nTPM]"	"Brain RNA - amygdala [nTPM]"	"Brain RNA - basal ganglia [nTPM]"	"Brain RNA - cerebellum [nTPM]"	"Brain RNA - cerebral cortex [nTPM]"	"Brain RNA - hippocampal formation [nTPM]"	"Brain RNA - hypothalamus [nTPM]"	"Brain RNA - medulla oblongata [nTPM]"	"Brain RNA - midbrain [nTPM]"	"Brain RNA - pons [nTPM]"	"Brain RNA - spinal cord [nTPM]"	"Brain RNA - thalamus [nTPM]"	"Brain RNA - white matter [nTPM]"	"Single Cell Type RNA - Adipocytes [nTPM]"	"Single Cell Type RNA - Alveolar cells type 1 [nTPM]"	"Single Cell Type RNA - Alveolar cells type 2 [nTPM]"	"Single Cell Type RNA - Astrocytes [nTPM]"	"Single Cell Type RNA - B-cells [nTPM]"	"Single Cell Type RNA - Basal keratinocytes [nTPM]"	"Single Cell Type RNA - Basal prostatic cells [nTPM]"	"Single Cell Type RNA - Basal respiratory cells [nTPM]"	"Single Cell Type RNA - Basal squamous epithelial cells [nTPM]"	"Single Cell Type RNA - Bipolar cells [nTPM]"	"Single Cell Type RNA - Breast glandular cells [nTPM]"	"Single Cell Type RNA - Breast myoepithelial cells [nTPM]"	"Single Cell Type RNA - Cardiomyocytes [nTPM]"	"Single Cell Type RNA - Cholangiocytes [nTPM]"	"Single Cell Type RNA - Club cells [nTPM]"	"Single Cell Type RNA - Collecting duct cells [nTPM]"	"Single Cell Type RNA - Cone photoreceptor cells [nTPM]"	"Single Cell Type RNA - Cytotrophoblasts [nTPM]"	"Single Cell Type RNA - dendritic cells [nTPM]"	"Single Cell Type RNA - Distal enterocytes [nTPM]"	"Single Cell Type RNA - Distal tubular cells [nTPM]"	"Single Cell Type RNA - Ductal cells [nTPM]"	"Single Cell Type RNA - Early spermatids [nTPM]"	"Single Cell Type RNA - Endometrial ciliated cells [nTPM]"	"Single Cell Type RNA - Endometrial stromal cells [nTPM]"	"Single Cell Type RNA - Endothelial cells [nTPM]"	"Single Cell Type RNA - Enteroendocrine cells [nTPM]"	"Single Cell Type RNA - Erythroid cells [nTPM]"	"Single Cell Type RNA - Excitatory neurons [nTPM]"	"Single Cell Type RNA - Exocrine glandular cells [nTPM]"	"Single Cell Type RNA - Extravillous trophoblasts [nTPM]"	"Single Cell Type RNA - Fibroblasts [nTPM]"	"Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]"	"Single Cell Type RNA - Glandular and luminal cells [nTPM]"	"Single Cell Type RNA - granulocytes [nTPM]"	"Single Cell Type RNA - Granulosa cells [nTPM]"	"Single Cell Type RNA - Hepatic stellate cells [nTPM]"	"Single Cell Type RNA - Hepatocytes [nTPM]"	"Single Cell Type RNA - Hofbauer cells [nTPM]"	"Single Cell Type RNA - Horizontal cells [nTPM]"	"Single Cell Type RNA - Inhibitory neurons [nTPM]"	"Single Cell Type RNA - Intestinal goblet cells [nTPM]"	"Single Cell Type RNA - Ionocytes [nTPM]"	"Single Cell Type RNA - Kupffer cells [nTPM]"	"Single Cell Type RNA - Langerhans cells [nTPM]"	"Single Cell Type RNA - Late spermatids [nTPM]"	"Single Cell Type RNA - Leydig cells [nTPM]"	"Single Cell Type RNA - Macrophages [nTPM]"	"Single Cell Type RNA - Melanocytes [nTPM]"	"Single Cell Type RNA - Microglial cells [nTPM]"	"Single Cell Type RNA - monocytes [nTPM]"	"Single Cell Type RNA - Muller glia cells [nTPM]"	"Single Cell Type RNA - NK-cells [nTPM]"	"Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]"	"Single Cell Type RNA - Oligodendrocytes [nTPM]"	"Single Cell Type RNA - Pancreatic endocrine cells [nTPM]"	"Single Cell Type RNA - Paneth cells [nTPM]"	"Single Cell Type RNA - Peritubular cells [nTPM]"	"Single Cell Type RNA - Plasma cells [nTPM]"	"Single Cell Type RNA - Prostatic glandular cells [nTPM]"	"Single Cell Type RNA - Proximal enterocytes [nTPM]"	"Single Cell Type RNA - Proximal tubular cells [nTPM]"	"Single Cell Type RNA - Respiratory ciliated cells [nTPM]"	"Single Cell Type RNA - Rod photoreceptor cells [nTPM]"	"Single Cell Type RNA - Sertoli cells [nTPM]"	"Single Cell Type RNA - Skeletal myocytes [nTPM]"	"Single Cell Type RNA - Smooth muscle cells [nTPM]"	"Single Cell Type RNA - Spermatocytes [nTPM]"	"Single Cell Type RNA - Spermatogonia [nTPM]"	"Single Cell Type RNA - Squamous epithelial cells [nTPM]"	"Single Cell Type RNA - Suprabasal keratinocytes [nTPM]"	"Single Cell Type RNA - Syncytiotrophoblasts [nTPM]"	"Single Cell Type RNA - T-cells [nTPM]"	"Single Cell Type RNA - Theca cells [nTPM]"	"Single Cell Type RNA - Undifferentiated cells [nTPM]"	"Single Cell Type RNA - Urothelial cells [nTPM]"
BRAF	BRAF1	ENSG00000157764	"B-Raf proto-oncogene, serine/threonine kinase"	P15056	7	140719327-140924929	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins"		"Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Cardiomyopathy, Deafness, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Mental retardation, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Excitatory neurons: 252.3;Inhibitory neurons: 242.4;Oligodendrocyte precursor cells: 206.1;Oligodendrocytes: 202.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001328, CAB004552, HPA071048"	Approved		Approved	Vesicles,Cytosol		No	No			"Cluster 15: NK-cells - Transcription"	"Cluster 34: Non-specific - Transcription"	"Cluster 29: U-266 - Adaptive immune response"	"Cluster 52: Non-specific - Transcription"	Vesicles	Cytosol	"CAB004552: AB_626760, HPA001328: AB_1078296, HPA071048: AB_2686336"	"unprognostic (2.98e-3)"	"unprognostic (5.66e-2)"	"unprognostic (2.20e-2)"	"unprognostic (2.66e-3)"	"unprognostic (2.44e-1)"	"unprognostic (1.48e-2)"	"unprognostic (2.07e-2)"	"unprognostic (4.23e-2)"	"unprognostic (4.07e-2)"	"unprognostic (1.58e-2)"	"unprognostic (6.53e-2)"	"unprognostic (1.91e-2)"	"unprognostic (3.79e-3)"	"unprognostic (2.08e-1)"	"unprognostic (1.76e-1)"	"unprognostic (8.01e-2)"	"unprognostic (5.46e-2)"	8.8	5.8	6.3	5.6	7.7	15.9	8.8	12.5	8.7	8.2	5.4	8.6	4.7	8.3	8.3	7.5	8.0	5.8	7.6	8.3	6.7	7.6	6.6	9.9	6.9	4.0	3.6	9.8	8.3	11.5	9.0	7.2	4.6	8.2	5.4	17.0	7.2	5.9	8.6	10.4	6.9	6.0	3.1	6.7	7.8	13.7	5.2	8.7	10.2	8.4	6.4	9.9	8.5	6.7	6.3	5.2	7.7	9.4	9.1	11.8	12.3	6.8	7.5	5.4	7.6	5.7	6.7	10.8	5.0	7.3	8.4	3.4	6.8	5.5	10.0	9.8	5.4	7.1	5.1	5.2	7.6	11.7	6.8	7.9	6.1	6.0	12.0	8.2	6.6	7.7	11.3	19.1	9.8	3.3	15.6	12.0	6.9	6.2	3.1	10.1	6.5	8.9	5.3	11.9	8.9	7.3	7.9	4.9	7.3	7.5	4.5	7.8	9.7	5.9	4.3	12.9	5.5	21.6	12.9	16.7	9.7	11.3	6.6	1.9	1.0	4.1	1.5	0.9	1.0	1.3	1.5	1.2	0.8	1.1	2.6	1.3	2.0	3.5	1.3	1.0	1.5	0.6	6.3	7.7	12.5	8.7	8.3	6.7	4.0	3.6	4.6	3.1	5.2	6.7	43.4	22.4	45.7	151.1	58.4	21.5	24.6	6.0	23.3	29.7	31.2	21.2	19.8	10.0	18.7	25.8	35.5	15.7	73.5	8.8	7.9	14.3	68.6	50.6	37.4	23.4	19.2	14.9	252.3	9.8	12.9	22.0	21.9	69.2	24.7	45.5	9.3	9.6	9.4	25.2	242.4	9.8	8.2	13.6	37.1	36.5	16.4	30.1	16.0	126.5	14.6	11.3	15.5	206.1	202.6	15.4	8.1	10.1	48.7	23.8	8.0	13.4	20.0	33.0	6.6	24.1	24.7	43.8	26.0	14.5	24.0	75.5	41.4	30.9	8.7	33.4
CDK4	PSK-J3	ENSG00000135446	"Cyclin dependent kinase 4"	P11802	12	57747727-57756013	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, Cell division"	"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Cancer enriched"	"Detected in all"	5	"glioma: 175.8"	"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Group enriched"	"Detected in all"	10	"HBEC3-KT: 2594.8;LHCN-M2: 2819.4;RH-30: 8902.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA006024, CAB013116, CAB069405"	Supported		Supported	"Nucleoplasm,Nuclear membrane,Nucleoli,Cytosol"		NA	NA			"Cluster 12: Non-specific - Basic cellular processes"	"Cluster 89: Fibroblasts - ECM organization"	"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction"	"Cluster 39: Non-specific - Basic cellular processes"	Cytosol	"Nucleoplasm, Nuclear membrane, Nucleoli"	"CAB013116: AB_2536376, CAB069405: AB_1613464, HPA006024: AB_2667497"	"unprognostic (8.88e-2)"	"unprognostic (2.53e-1)"	"unprognostic (5.27e-2)"	"unprognostic (9.01e-2)"	"unprognostic (2.21e-1)"	"unprognostic (1.10e-1)"	"prognostic unfavorable (2.09e-7)"	"unprognostic (7.39e-2)"	"unprognostic (3.23e-3)"	"unprognostic (2.93e-2)"	"unprognostic (3.19e-2)"	"unprognostic (9.10e-2)"	"prognostic unfavorable (3.15e-5)"	"unprognostic (3.32e-1)"	"unprognostic (1.67e-1)"	"unprognostic (3.64e-1)"	"unprognostic (1.57e-2)"	69.7	87.8	35.0	52.8	37.9	72.0	76.6	37.7	36.9	84.3	35.9	62.6	40.2	97.4	64.2	57.2	69.4	57.1	58.9	33.6	37.1	58.5	51.5	58.0	66.8	37.1	36.9	97.3	70.9	63.5	67.7	52.4	36.8	52.7	63.3	14.5	54.4	54.1	48.2	58.9	47.2	80.4	37.3	51.5	54.8	24.1	37.3	67.6	66.0	52.7	70.6	71.6	60.7	37.6	207.1	235.7	295.7	268.0	253.7	220.7	210.4	116.1	347.9	468.5	385.7	338.2	189.1	297.4	200.2	173.6	293.2	158.0	396.3	2594.8	354.9	150.9	209.0	275.4	149.5	237.9	297.0	309.7	182.5	221.5	180.9	294.2	326.7	326.4	304.8	280.0	301.3	242.7	2819.4	304.9	296.7	256.5	347.0	208.0	249.8	267.3	8902.5	272.1	147.2	320.6	271.2	251.7	205.3	150.2	310.0	195.1	202.8	380.7	146.1	233.6	217.0	265.8	233.1	122.2	206.1	450.8	214.1	291.3	286.9	9.5	46.5	10.3	79.6	65.6	81.8	93.5	70.0	72.5	66.7	90.0	93.0	84.4	4.4	56.6	41.9	84.9	57.0	73.6	35.0	37.9	37.7	36.9	33.6	37.1	37.1	36.9	36.8	37.3	37.3	37.6	47.1	22.4	30.8	7.8	40.0	89.7	78.6	83.4	74.0	15.9	67.2	82.2	0.7	51.5	35.3	47.8	10.4	82.9	26.1	15.9	70.5	93.1	13.5	14.9	77.7	50.8	45.6	98.0	5.2	62.5	134.5	79.4	28.5	22.6	69.1	60.2	39.7	35.8	132.9	18.5	6.7	42.2	40.7	25.1	44.1	8.0	64.0	31.2	53.4	6.5	41.9	51.4	29.9	5.5	8.0	48.3	18.9	63.2	57.8	113.9	14.0	80.9	7.4	17.9	32.9	62.1	61.9	32.1	48.3	74.5	86.1	46.8	32.3	78.8	78.7	49.4
CDKN2A	"ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, p14, p14ARF, p16, p16INK4a, p19, p19Arf"	ENSG00000147889	"Cyclin dependent kinase inhibitor 2A"	"P42771, Q8N726"	9	21967752-21995301	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Apoptosis, Cell cycle, rRNA processing, Transcription, Transcription regulation, Ubl conjugation pathway"	DNA-binding	"Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"choroid plexus: 31.7;pituitary gland: 33.7"	"Cell type enhanced"	"Detected in many"		"Basal respiratory cells: 170.1;Club cells: 145.9;Early spermatids: 227.5;Late spermatids: 447.9;Pancreatic endocrine cells: 417.7;Respiratory ciliated cells: 221.9"	"Cancer enhanced"	"Detected in all"		"cervical cancer: 49.9;ovarian cancer: 57.6"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"T-reg: 37.4"	"Group enriched"	"Detected in many"	6	"B-cells: 15.6;T-cells: 37.4"	"Cell line enhanced"	"Detected in many"		"CAPAN-2: 289.2;HEK 293: 389.7;HeLa: 311.1;SK-MEL-30: 318.7"					"Low region specificity"	"Detected in some"			"CAB000093, CAB000445, CAB018232, HPA047838"	Enhanced		Supported	Nucleoli		NA	NA		18000	"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 26: Pituitary gland - Hormone signaling"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 16: Pancreatic endocrine cells - Mixed function"	Nucleoli		"CAB000093: AB_442119, CAB000445: , CAB018232: AB_785018, HPA047838: AB_2680174"	"unprognostic (3.41e-2)"	"unprognostic (4.51e-2)"	"unprognostic (3.00e-3)"	"prognostic unfavorable (1.82e-7)"	"unprognostic (5.22e-2)"	"prognostic favorable (5.19e-4)"	"prognostic unfavorable (2.17e-4)"	"unprognostic (1.25e-2)"	"unprognostic (1.05e-1)"	"unprognostic (1.04e-1)"	"unprognostic (1.71e-1)"	"unprognostic (1.56e-2)"	"prognostic unfavorable (5.76e-7)"	"unprognostic (9.41e-2)"	"unprognostic (1.22e-2)"	"unprognostic (3.05e-2)"	"unprognostic (3.55e-1)"	3.7	10.1	7.4	1.7	8.3	1.3	3.1	5.9	8.5	1.1	31.7	1.9	0.8	0.7	1.0	7.4	2.2	0.5	0.7	6.7	6.4	0.5	0.7	2.3	2.1	7.4	5.8	0.8	1.5	2.1	33.7	2.6	7.2	2.1	0.7	0.1	1.6	1.6	0.6	0.9	3.6	0.3	6.2	5.5	3.9	14.8	8.0	2.1	1.3	0.0	2.5	2.4	2.3	9.2	11.8	0.0	1.7	82.2	0.8	0.9	39.1	15.9	0.0	111.7	196.0	19.1	289.2	47.1	167.7	9.5	0.0	36.0	34.3	211.0	91.4	212.2	389.7	0.1	311.1	13.6	8.8	22.4	17.3	21.2	0.0	112.2	61.9	236.3	11.7	0.0	0.1	188.4	105.7	0.8	1.9	0.0	2.6	24.2	185.9	0.2	80.2	166.3	23.4	0.0	195.2	14.0	219.9	36.6	318.7	9.4	42.8	0.7	39.5	0.9	2.6	0.3	0.5	84.7	49.6	177.8	0.2	62.9	1.0	1.5	2.1	0.3	9.9	1.3	14.1	11.1	11.4	17.6	0.3	15.6	0.6	6.7	0.5	0.8	4.2	0.0	37.4	3.6	7.4	8.3	5.9	8.5	6.7	6.4	7.4	5.8	7.2	6.2	8.0	9.2	1.6	0.0	0.0	1.0	11.5	1.8	2.3	170.1	0.0	0.6	6.1	10.4	4.2	0.0	145.9	11.0	0.0	27.9	6.2	8.1	0.0	29.7	227.5	36.4	6.7	2.6	70.9	0.0	1.2	26.4	43.8	7.7	0.0	6.2	4.5	4.6	1.4	0.3	7.6	0.0	3.5	6.3	122.1	10.5	4.2	447.9	3.1	2.9	8.8	7.5	16.2	0.9	5.2	4.5	6.6	417.7	12.1	1.9	38.7	35.4	32.8	0.0	221.9	0.1	0.0	1.1	20.8	7.2	6.2	7.2	0.4	9.2	12.7	11.0	3.8	54.4
CDKN2B	"CDK4I, INK4B, MTS2, P15, p15INK4b, TP15"	ENSG00000147883	"Cyclin dependent kinase inhibitor 2B"	P42772	9	22002903-22009305	"Human disease related genes, Predicted intracellular proteins"	"Cell cycle"		"Tumor suppressor"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"esophagus: 36.2;intestine: 30.9"	"Cell type enhanced"	"Detected in many"		"Distal enterocytes: 240.7;Pancreatic endocrine cells: 164.5;Proximal enterocytes: 139.0;Squamous epithelial cells: 142.0;Urothelial cells: 241.6"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	10	"classical monocyte: 3.3;intermediate monocyte: 3.3;non-classical monocyte: 9.0"	"Lineage enriched"	"Detected in single"	17	"monocytes: 9.0"	"Cell line enhanced"	"Detected in many"		"ASC TERT1: 38.1;HaCaT: 35.0;HeLa: 33.9;hTERT-RPE1: 60.1;SiHa: 48.0;SK-MEL-30: 35.7"	"Low region specificity"	"Detected in some"			"Low region specificity"	"Detected in all"			"CAB000349, HPA052838, HPA063327"	Uncertain		Approved	Nucleoplasm		NA	NA			"Cluster 14: Monocytes - Unknown function"	"Cluster 37: Intestine - Unknown function"	"Cluster 20: HeLa - Mitochondria"	"Cluster 53: Intestinal epithelial cells - Unknown function"	Nucleoplasm		"CAB000349: , HPA052838: , HPA063327: AB_2684987"	"unprognostic (2.30e-1)"	"unprognostic (9.23e-2)"	"unprognostic (2.19e-1)"	"prognostic unfavorable (4.47e-6)"	"unprognostic (2.10e-1)"	"unprognostic (7.40e-2)"	"prognostic unfavorable (1.49e-4)"	"unprognostic (2.01e-1)"	"unprognostic (3.03e-2)"	"unprognostic (3.19e-2)"	"unprognostic (1.13e-1)"	"unprognostic (1.36e-1)"	"prognostic unfavorable (1.03e-4)"	"unprognostic (9.14e-3)"	"unprognostic (1.29e-1)"	"unprognostic (2.72e-1)"	"unprognostic (7.28e-2)"	18.7	1.9	2.0	2.9	1.8	0.4	8.6	1.1	1.9	9.6	9.1	22.4	21.7	3.8	0.6	36.2	1.7	2.4	1.0	1.6	2.2	1.2	1.2	12.6	1.1	2.7	1.5	0.9	1.2	3.3	3.5	2.3	2.3	3.6	19.7	2.8	6.7	4.7	7.2	12.9	30.9	2.1	1.7	4.6	6.0	5.3	2.4	0.8	1.1	1.1	8.1	7.9	20.2	2.4	0.0	0.0	0.3	2.1	28.2	38.1	0.7	1.8	0.0	4.6	12.6	3.6	10.3	0.0	3.4	2.3	0.0	35.0	0.8	6.9	5.5	2.6	9.7	0.0	33.9	1.5	14.4	1.1	6.1	8.1	0.0	6.5	25.8	60.1	4.4	0.0	0.0	17.1	7.3	2.8	0.0	0.1	1.7	1.7	19.5	0.0	2.4	0.7	10.0	0.0	5.4	0.1	48.0	11.5	35.7	25.8	3.0	0.0	14.8	0.0	0.7	0.1	0.0	13.5	8.4	0.1	0.0	1.0	0.0	0.0	3.3	0.0	0.1	3.3	0.0	0.0	0.2	0.3	0.5	0.0	0.0	0.1	0.0	0.0	9.0	0.0	0.0	1.0	2.0	1.8	1.1	1.9	1.6	2.2	2.7	1.5	2.3	1.7	2.4	2.4	3.5	67.3	6.7	0.3	2.9	5.4	27.0	40.5	5.7	3.2	6.4	9.8	3.1	1.5	37.5	5.5	0.0	1.2	3.2	240.7	0.0	57.7	11.3	31.8	7.5	4.1	7.7	0.0	0.1	38.2	0.8	11.5	30.5	37.2	0.0	0.4	1.8	0.1	1.2	0.0	0.5	31.6	14.2	17.6	3.8	2.7	0.6	5.6	3.6	2.8	3.2	4.8	0.0	1.0	0.5	164.5	75.6	1.2	2.1	65.3	139.0	0.1	17.9	7.2	0.0	2.7	8.9	13.8	3.5	142.0	24.2	3.1	2.9	1.2	23.3	241.6
FAS	"APO-1, APT1, CD95, FAS1, TNFRSF6"	ENSG00000026103	"Fas cell surface death receptor"	P25445	10	88990531-89017059	"Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins"	Apoptosis	"Calmodulin-binding, Receptor"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Basal prostatic cells: 109.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"neutrophil: 114.7"	"Group enriched"	"Detected in all"	5	"granulocytes: 114.7;T-cells: 96.2"	"Cell line enhanced"	"Detected in many"		"HDLM-2: 83.4;Karpas-707: 109.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA027444	Uncertain		Supported	"Nuclear bodies,Plasma membrane,Cytosol"	"Secreted to blood"	NA	NA	11900000	420000	"Cluster 31: Non-specific - Inflammatory response"	"Cluster 85: Liver - Metabolism"	"Cluster 2: Karpas-707 - Immune response"	"Cluster 24: Non-specific - Transcription regulation"	"Plasma membrane"	"Nuclear bodies, Cytosol"	"HPA027444: AB_10601378"	"unprognostic (6.84e-2)"	"unprognostic (2.88e-3)"	"unprognostic (8.38e-3)"	"unprognostic (1.94e-1)"	"unprognostic (2.35e-2)"	"unprognostic (9.56e-2)"	"unprognostic (7.00e-2)"	"unprognostic (2.05e-1)"	"unprognostic (3.01e-1)"	"unprognostic (7.70e-2)"	"unprognostic (1.26e-2)"	"unprognostic (1.98e-1)"	"unprognostic (1.52e-3)"	"unprognostic (2.10e-1)"	"unprognostic (2.32e-2)"	"unprognostic (4.95e-3)"	"unprognostic (1.65e-1)"	14.1	26.3	3.6	17.0	3.6	20.8	10.9	2.9	4.7	12.7	2.8	16.4	7.0	12.8	10.3	10.8	14.8	15.7	7.5	3.6	3.7	7.2	23.3	21.7	18.9	4.6	3.1	20.1	3.7	2.7	3.7	10.4	4.0	8.9	23.3	3.3	6.5	9.3	2.3	9.4	9.2	15.0	3.5	11.2	4.4	2.6	3.9	14.4	7.3	2.6	15.6	12.9	10.2	4.3	22.7	8.2	5.4	13.9	37.0	51.3	0.0	51.8	50.2	1.7	9.1	0.1	23.4	4.7	19.0	52.1	9.6	4.0	1.0	44.8	3.2	83.4	8.7	0.4	5.2	14.7	31.6	3.4	1.6	69.2	38.7	31.4	66.0	24.5	4.7	17.8	0.0	109.0	44.0	1.4	6.4	3.4	0.6	0.2	1.8	1.4	0.5	5.0	60.7	7.3	0.4	0.2	7.7	0.0	0.8	7.0	13.9	1.0	9.5	15.8	9.0	15.2	12.3	45.3	5.3	0.4	11.8	10.2	4.5	43.1	9.4	30.9	9.9	12.3	13.8	7.5	27.6	19.6	11.5	4.0	3.1	10.0	114.7	3.1	22.1	0.2	96.2	12.8	3.6	3.6	2.9	4.7	3.6	3.7	4.6	3.1	4.0	3.5	3.9	4.3	10.3	57.7	13.8	40.1	12.8	45.9	109.7	53.1	39.9	0.0	5.5	9.5	3.5	12.8	27.5	9.2	0.0	0.4	16.3	24.9	0.0	6.3	11.3	9.2	22.3	8.9	8.4	9.5	8.8	4.3	0.2	35.4	8.6	15.5	3.8	4.9	2.2	19.3	5.5	1.7	2.8	14.4	8.2	7.0	31.7	4.9	19.0	17.7	12.4	17.8	20.9	14.5	10.3	8.0	0.7	6.5	8.7	13.9	32.2	46.0	15.6	14.4	26.3	0.7	6.6	26.8	29.1	11.3	1.1	28.5	43.9	0.4	48.4	11.8	24.4	30.0
HRAS	HRAS1	ENSG00000174775	"HRas proto-oncogene, GTPase"	P01112	11	532242-537287	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins"		Hydrolase	"Cancer-related genes, Disease variant, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Suprabasal keratinocytes: 145.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"non-classical monocyte: 4.0"	"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002015, HPA049830, HPA070222"	Approved		Approved	Nucleoplasm,Cytosol		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 27: Brain & Skin - Unknown function"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 22: Epithelial cell types - Mixed function"	"Nucleoplasm, Cytosol"		"CAB002015: , HPA049830: AB_2680903, HPA070222: "	"unprognostic (3.06e-2)"	"unprognostic (2.98e-2)"	"unprognostic (7.01e-2)"	"unprognostic (3.08e-3)"	"unprognostic (3.49e-3)"	"unprognostic (3.87e-1)"	"prognostic unfavorable (2.32e-4)"	"unprognostic (1.07e-1)"	"unprognostic (2.25e-1)"	"unprognostic (1.50e-1)"	"unprognostic (2.88e-3)"	"unprognostic (9.85e-2)"	"unprognostic (2.81e-1)"	"unprognostic (1.85e-1)"	"unprognostic (1.80e-1)"	"unprognostic (1.58e-2)"	"unprognostic (1.38e-1)"	28.1	24.6	64.6	3.5	67.2	2.9	27.0	62.1	86.8	30.4	58.3	34.3	2.8	23.6	12.5	80.1	18.9	3.6	56.8	64.4	64.6	33.8	21.8	27.1	4.3	65.6	65.3	20.0	20.5	13.1	38.2	9.0	66.9	38.3	6.9	10.2	27.3	12.3	59.0	69.9	19.5	8.9	64.2	20.6	24.2	16.5	64.8	9.2	20.5	25.2	10.2	34.5	44.2	65.4	59.0	105.6	44.2	25.6	22.2	17.5	39.6	49.9	25.1	64.5	29.5	62.4	29.7	20.4	10.9	63.2	60.7	43.7	46.0	114.1	19.3	19.5	108.4	6.6	43.7	56.1	38.5	13.9	12.0	28.3	118.0	42.0	51.5	19.6	31.5	34.3	29.7	32.3	40.9	110.6	34.0	50.5	26.5	39.9	94.5	31.6	40.7	18.2	47.0	33.2	87.6	43.7	25.5	55.4	17.9	31.5	43.3	14.8	35.4	47.3	44.7	16.4	39.7	20.3	17.7	15.4	39.1	17.0	38.3	0.0	0.5	0.6	0.8	0.7	0.4	0.3	0.9	0.8	0.7	2.0	0.9	0.3	0.0	0.1	4.0	0.9	1.5	0.2	64.6	67.2	62.1	86.8	64.4	64.6	65.6	65.3	66.9	64.2	64.8	65.4	51.3	12.8	10.7	9.1	18.0	131.2	101.7	25.4	82.0	46.0	38.8	75.7	25.2	22.8	11.2	35.0	18.8	78.8	21.5	72.2	74.3	35.2	1.6	36.1	28.6	32.0	29.3	11.2	9.8	37.4	63.4	25.9	33.6	34.1	2.5	26.8	22.9	17.4	39.9	48.8	10.6	26.5	4.1	11.7	38.4	7.9	17.1	21.3	64.0	10.3	12.8	50.8	11.3	4.0	12.3	48.2	30.9	23.0	26.5	61.2	30.8	54.6	20.0	37.6	32.9	20.3	40.3	5.4	21.4	118.1	145.9	78.1	22.0	18.8	26.2	106.4
JUNB		ENSG00000171223	"JunB proto-oncogene, AP-1 transcription factor subunit"	P17275	19	12791486-12793315	"Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	DNA-binding		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"neutrophil: 679.4"	"Group enriched"	"Detected in all"	5	"granulocytes: 679.4;monocytes: 182.7"	"Cell line enhanced"	"Detected in all"		"HDLM-2: 629.0;U-266/70: 256.4;U-266/84: 411.4"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004464, HPA019149"	Approved		Supported	Nucleoplasm		NA	NA			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 89: Fibroblasts - ECM organization"	"Cluster 44: HDLM-2 - Immune response"	"Cluster 7: Non-specific - Mitochondria"	Nucleoplasm		"CAB004464: AB_2130023, HPA019149: AB_1852053"	"unprognostic (1.03e-2)"	"unprognostic (1.10e-1)"	"unprognostic (2.11e-1)"	"unprognostic (1.04e-1)"	"unprognostic (7.17e-2)"	"unprognostic (1.77e-2)"	"unprognostic (2.19e-1)"	"unprognostic (2.13e-2)"	"unprognostic (1.12e-1)"	"prognostic unfavorable (3.65e-4)"	"unprognostic (1.79e-1)"	"unprognostic (9.78e-2)"	"prognostic unfavorable (1.05e-4)"	"unprognostic (7.20e-2)"	"unprognostic (7.06e-2)"	"unprognostic (3.77e-1)"	"unprognostic (1.02e-1)"	722.8	259.5	22.9	110.3	28.0	455.2	248.5	90.1	65.2	283.3	30.4	287.0	52.8	130.1	2.2	449.1	874.8	92.6	383.5	28.3	68.8	184.2	279.0	399.2	65.0	83.5	29.8	649.5	150.0	20.8	351.9	39.4	33.6	195.0	22.0	32.0	131.6	56.1	144.6	605.9	145.0	58.1	51.5	153.3	309.8	30.0	31.3	78.8	198.7	73.3	12.9	333.0	330.6	34.8	52.9	10.4	2.8	6.4	11.3	27.4	10.2	22.8	19.2	11.0	10.0	6.8	30.4	18.2	77.4	8.4	33.5	98.5	2.5	34.3	1.2	629.0	9.9	18.0	42.2	9.0	15.1	24.3	80.5	34.9	97.6	10.0	7.5	22.0	5.3	12.9	48.1	32.6	3.6	158.8	16.8	147.5	1.7	36.1	40.0	22.4	7.7	38.8	7.5	65.5	23.7	36.0	98.4	59.5	30.5	1.7	10.5	27.0	17.6	32.2	18.7	64.3	28.9	256.4	411.4	17.1	37.7	62.7	8.9	29.1	132.2	132.2	33.4	182.7	33.4	30.6	36.8	42.0	87.1	25.4	25.5	28.5	679.4	18.6	177.2	7.9	38.7	124.1	22.9	28.0	90.1	65.2	28.3	68.8	83.5	29.8	33.6	51.5	31.3	34.8	3158.0	115.4	423.2	130.2	1751.7	1463.9	1778.3	2367.7	1985.1	81.0	1296.9	1693.1	374.0	474.7	707.4	154.5	39.6	129.7	1766.9	819.7	49.0	833.3	9.5	468.5	1091.4	1469.5	1502.1	244.8	8.7	546.7	224.7	2182.3	1060.1	627.8	510.5	310.0	852.4	84.6	1178.4	21.9	4.4	1029.3	740.6	674.1	2747.6	27.9	815.2	1583.3	894.6	20.6	379.3	634.6	115.4	4.5	2.4	1026.7	875.3	263.3	842.5	1036.7	701.0	84.2	337.3	168.8	1163.6	2566.6	2624.1	9.4	10.5	1164.3	1804.1	440.3	2362.6	417.0	687.7	472.6
KRAS	"KRAS1, KRAS2"	ENSG00000133703	"KRAS proto-oncogene, GTPase"	P01116	12	25205246-25250936	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins"		Hydrolase	"Cancer-related genes, Cardiomyopathy, Deafness, Disease variant, Ectodermal dysplasia, Mental retardation, Proto-oncogene"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA049830	Approved					NA	NA		3300000	"Cluster 18: Basophils - Vesicular transport"	"Cluster 75: Bone marrow - mRNA splicing & Cell cycle"	"Cluster 5: NTERA-2 - Transcription"	"Cluster 22: Epithelial cell types - Mixed function"			"HPA049830: AB_2680903"	"unprognostic (2.24e-2)"	"unprognostic (2.16e-2)"	"unprognostic (4.86e-3)"	"unprognostic (1.08e-2)"	"unprognostic (7.39e-2)"	"unprognostic (1.51e-1)"	"unprognostic (1.47e-2)"	"unprognostic (3.74e-2)"	"unprognostic (1.79e-1)"	"unprognostic (2.39e-1)"	"prognostic unfavorable (3.59e-4)"	"unprognostic (6.42e-2)"	"prognostic favorable (2.75e-5)"	"unprognostic (1.95e-2)"	"unprognostic (2.37e-1)"	"unprognostic (2.81e-2)"	"unprognostic (9.97e-2)"	11.8	9.1	11.0	16.2	12.2	27.8	10.0	11.7	12.3	9.5	4.6	22.0	14.0	11.0	6.8	19.3	7.4	13.1	8.6	12.5	12.0	11.7	15.3	13.2	17.9	8.5	9.7	8.0	12.6	11.1	5.7	17.0	8.7	11.8	23.0	22.7	11.9	8.3	7.6	13.6	19.5	13.6	8.1	12.0	20.3	8.9	12.9	17.2	10.8	10.3	17.4	16.2	11.4	8.6	15.9	14.3	39.4	20.7	14.1	19.9	68.9	17.3	22.8	18.0	21.9	51.5	30.7	38.7	10.4	32.0	23.4	18.6	44.9	17.3	34.3	26.7	15.0	37.6	17.6	15.6	15.8	32.8	25.6	18.1	25.5	21.9	20.2	33.6	27.1	28.7	28.0	17.3	27.6	14.1	46.8	56.6	87.6	25.3	7.4	43.4	39.9	59.9	27.2	22.4	11.2	32.4	20.5	24.9	21.8	97.4	28.9	26.9	28.1	18.7	24.8	38.2	22.0	16.4	28.5	41.9	15.4	20.0	15.0	31.2	8.1	13.7	11.6	16.4	7.9	10.7	10.1	13.1	7.9	10.5	13.8	12.4	19.2	11.2	22.4	7.8	7.6	5.8	11.0	12.2	11.7	12.3	12.5	12.0	8.5	9.7	8.7	8.1	12.9	8.6	73.7	48.1	32.1	16.6	90.8	100.9	96.4	57.2	72.3	63.4	59.9	38.0	16.3	64.3	53.6	38.6	73.0	94.2	66.0	161.9	58.7	77.5	3.9	45.4	40.8	77.3	78.8	60.2	42.0	91.8	21.4	50.1	98.4	53.4	24.1	26.6	77.8	56.9	51.5	92.5	45.3	92.9	36.7	53.9	83.7	5.9	40.7	75.3	62.2	28.1	82.9	41.7	49.4	19.6	16.6	114.2	104.7	51.6	85.0	130.1	63.0	52.3	42.5	65.8	26.3	53.7	52.2	53.0	40.3	93.0	155.7	139.1	83.0	36.5	96.7	176.9
MITF	"bHLHe32, MI, WS2, WS2A"	ENSG00000187098	"Melanocyte inducing transcription factor"	O75030	3	69739464-69968336	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, Developmental protein, DNA-binding"	"Albinism, Cancer-related genes, Deafness, Disease variant, Microphthalmia, Osteopetrosis, Waardenburg syndrome"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Inhibitory neurons: 133.5;Melanocytes: 585.2;Oligodendrocyte precursor cells: 166.9;Oligodendrocytes: 240.3"	"Cancer enriched"	"Detected in all"	4	"melanoma: 39.2"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	5	"basophil: 5.2;classical monocyte: 9.4;intermediate monocyte: 3.3;myeloid DC: 6.1;non-classical monocyte: 5.9"	"Group enriched"	"Detected in many"	6	"dendritic cells: 6.1;granulocytes: 5.2;monocytes: 9.4"	"Cell line enhanced"	"Detected in many"		"HMC-1: 89.1;SK-MEL-30: 254.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002578, HPA003259"	Enhanced					NA	NA			"Cluster 14: Monocytes - Unknown function"	"Cluster 13: Striated muscle - Muscle contraction"	"Cluster 33: SK-MEL-30 - Melanocyte processes"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"			"CAB002578: AB_564111, HPA003259: AB_1079381"	"unprognostic (3.29e-1)"	"unprognostic (4.26e-2)"	"unprognostic (2.98e-2)"	"unprognostic (6.04e-2)"	"unprognostic (1.03e-1)"	"unprognostic (3.25e-1)"	"unprognostic (1.04e-2)"	"unprognostic (1.09e-1)"	"unprognostic (2.75e-1)"	"unprognostic (5.31e-3)"	"unprognostic (3.87e-3)"	"unprognostic (1.94e-1)"	"prognostic favorable (8.35e-10)"	"unprognostic (6.37e-2)"	"unprognostic (1.08e-1)"	"unprognostic (2.04e-1)"	"unprognostic (1.73e-1)"	13.8	4.4	5.1	3.8	9.2	1.7	10.0	9.4	6.3	51.3	21.2	18.8	2.8	46.2	4.5	8.9	10.3	16.8	31.1	5.2	9.3	20.0	2.2	9.7	3.4	12.5	9.5	18.7	4.2	16.8	3.8	3.3	10.4	8.4	4.5	1.2	5.1	14.1	50.6	11.0	5.8	46.0	7.0	2.0	9.4	2.3	10.3	2.2	7.6	43.3	1.5	10.6	16.6	13.8	17.2	12.2	1.3	5.1	18.8	0.3	2.0	16.9	9.9	7.8	4.8	6.1	0.8	0.0	4.0	0.3	21.6	8.6	3.7	9.4	8.6	0.0	2.5	37.1	24.5	0.3	4.5	0.8	89.1	15.3	3.9	2.2	8.6	29.1	2.4	0.0	12.3	5.2	5.4	1.2	0.7	1.0	0.7	0.7	8.3	0.1	1.9	7.7	45.2	9.0	0.4	1.9	8.8	3.1	254.1	2.0	0.7	2.3	0.1	3.8	13.3	5.1	3.5	0.6	1.0	0.1	7.7	2.6	9.2	5.2	9.4	0.0	0.0	3.3	0.0	0.0	0.0	0.1	6.1	0.0	0.0	0.0	0.7	1.1	5.9	0.5	0.0	3.1	5.1	9.2	9.4	6.3	5.2	9.3	12.5	9.5	10.4	7.0	10.3	13.8	4.6	28.9	6.8	34.3	0.2	42.8	3.6	16.7	7.4	1.6	1.8	1.8	109.5	11.5	18.2	14.7	0.0	1.3	0.6	0.4	50.9	14.7	1.6	24.5	94.3	7.4	1.2	8.6	14.7	8.8	1.0	38.3	9.7	71.2	106.8	10.9	4.6	2.1	45.8	6.7	133.5	0.3	12.2	30.8	30.9	3.4	44.4	24.3	585.2	50.6	10.6	1.4	0.0	166.9	240.3	7.7	0.0	50.4	0.4	5.2	0.2	24.3	12.5	0.2	13.1	17.8	22.6	4.0	6.3	7.2	18.9	1.1	3.8	5.5	0.6	7.1
MYC	"bHLHe39, c-Myc, MYCC"	ENSG00000136997	"MYC proto-oncogene, bHLH transcription factor"	P01106	8	127735434-127742951	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, DNA-binding"	"Cancer-related genes, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"adipose tissue: 254.6;skin 1: 289.1"	"Cell type enhanced"	"Detected in many"		"Basal keratinocytes: 1013.3;Basal prostatic cells: 1080.5;Basal squamous epithelial cells: 1270.8;Squamous epithelial cells: 768.8;Suprabasal keratinocytes: 1070.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"RPMI-8226: 1069.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000084, CAB010307, HPA055893, HPA066556"	Approved		Enhanced	Nucleoplasm		NA	NA			"Cluster 32: T-cells - Unknown function"	"Cluster 31: Skin - Epidermis development"	"Cluster 25: RPMI-8226 - Immune response"	"Cluster 61: Squamous epithelial cells - Keratinization"	Nucleoplasm		"CAB000084: , CAB010307: AB_631274, HPA055893: AB_2682960, HPA066556: AB_2685691"	"unprognostic (1.45e-2)"	"unprognostic (4.00e-3)"	"unprognostic (3.94e-3)"	"unprognostic (2.41e-3)"	"unprognostic (8.14e-2)"	"unprognostic (3.36e-3)"	"unprognostic (5.80e-2)"	"unprognostic (4.94e-3)"	"unprognostic (1.59e-1)"	"prognostic unfavorable (7.52e-4)"	"unprognostic (5.19e-3)"	"unprognostic (9.86e-3)"	"prognostic unfavorable (5.49e-8)"	"unprognostic (7.85e-2)"	"unprognostic (4.66e-2)"	"unprognostic (2.48e-1)"	"prognostic unfavorable (4.96e-5)"	254.6	59.8	2.6	62.3	2.2	53.7	115.8	3.7	3.3	54.4	3.0	57.9	30.6	53.8	3.8	99.5	167.5	83.3	45.5	2.3	6.3	20.0	64.9	47.0	49.4	9.2	5.0	100.0	103.1	7.0	12.3	33.4	6.0	32.7	36.8	0.7	42.2	14.1	50.6	289.1	48.6	54.8	4.5	60.1	70.6	12.5	5.5	47.2	27.0	15.7	39.2	63.2	96.3	4.4	56.8	89.3	9.3	100.9	166.6	209.8	28.4	72.2	31.6	87.5	72.7	137.0	150.2	587.3	86.4	43.0	82.4	122.2	383.8	226.5	67.8	128.9	167.0	370.7	189.5	203.6	150.0	282.0	52.0	138.8	560.4	55.5	490.8	74.8	104.3	217.3	549.8	315.5	49.7	151.9	394.4	616.9	27.4	273.2	204.0	203.7	46.1	1069.6	79.2	61.9	660.7	64.9	32.6	270.7	195.9	17.5	106.4	172.2	120.5	63.4	71.6	49.7	87.2	5.5	8.7	275.9	55.3	286.2	30.8	3.0	39.5	0.7	31.5	36.0	161.5	92.0	114.3	67.4	33.5	71.4	195.2	128.0	4.1	85.5	26.9	1.4	95.6	88.9	2.6	2.2	3.7	3.3	2.3	6.3	9.2	5.0	6.0	4.5	5.5	4.4	218.0	57.7	70.4	0.7	108.0	1013.3	1080.5	278.9	1270.8	0.6	251.3	207.3	10.9	44.3	98.4	12.9	0.0	20.6	20.9	23.0	1.9	78.3	1.0	43.9	224.5	158.0	12.5	189.1	1.6	43.6	61.2	337.9	46.4	72.0	57.0	47.6	141.0	25.8	26.9	0.0	1.1	67.8	97.6	43.7	133.1	3.9	98.8	23.3	168.9	1.0	17.0	1.4	5.2	0.0	0.2	66.5	40.4	67.4	45.7	364.8	4.8	13.3	21.5	0.3	46.0	458.5	349.1	0.6	0.6	768.8	1070.1	5.9	75.0	56.0	117.7	409.4
NAV3	"KIAA0938, POMFIL1"	ENSG00000067798	"Neuron navigator 3"	Q8IVL0	12	77324641-78213010	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"			"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 17.3;ovary: 18.3"	"Group enriched"	"Detected in many"	6	"Astrocytes: 882.1;Excitatory neurons: 1473.6;Inhibitory neurons: 753.8;Microglial cells: 534.0;Oligodendrocyte precursor cells: 786.1"	"Low cancer specificity"	"Detected in many"			"Group enriched"	"Detected in many"	8	"amygdala: 9.7;basal ganglia: 15.0;cerebral cortex: 17.3;hippocampal formation: 13.6;white matter: 10.3"	"Immune cell enhanced"	"Detected in single"		"neutrophil: 1.0"	"Lineage enriched"	"Detected in single"	9	"granulocytes: 1.0"	"Cell line enhanced"	"Detected in many"		"hTEC/SVTERT24-B: 47.0;THP-1: 41.8;U-138 MG: 30.8;WM-115: 38.7"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA032111, HPA061392"	Approved		Approved	"Nuclear membrane,Cytosol"		NA	NA			"Cluster 17: Basophils - Unknown function"	"Cluster 10: Brain - Neuronal signaling"	"Cluster 10: BJ & FHDF - ECM organization"	"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling"	"Nuclear membrane"	Cytosol	"HPA032111: AB_10603881, HPA061392: "	"unprognostic (3.51e-1)"	"unprognostic (6.72e-2)"	"unprognostic (1.09e-2)"	"unprognostic (1.79e-1)"	"unprognostic (8.98e-2)"	"unprognostic (2.14e-1)"	"unprognostic (2.78e-1)"	"unprognostic (3.25e-2)"	"unprognostic (3.03e-2)"	"unprognostic (2.06e-2)"	"unprognostic (2.99e-1)"	"unprognostic (1.90e-1)"	"unprognostic (5.68e-7)"	"unprognostic (6.86e-3)"	"unprognostic (1.23e-1)"	"unprognostic (1.58e-2)"	"unprognostic (2.29e-3)"	3.8	4.8	9.7	1.0	15.0	0.5	4.0	0.9	17.3	1.2	0.0	1.7	0.3	2.0	2.9	1.9	2.2	5.1	1.9	13.6	0.0	0.4	1.0	3.3	0.6	0.7	0.4	18.3	0.5	0.4	3.1	2.2	0.0	2.1	0.8	5.2	0.9	2.5	1.3	2.6	0.6	2.5	1.4	8.0	0.8	2.8	1.6	1.9	1.2	3.4	0.4	3.3	1.7	10.3	3.5	8.7	0.6	0.2	8.5	18.1	0.3	26.5	20.9	10.7	5.3	1.7	0.6	0.2	1.9	22.0	7.2	2.5	7.8	4.0	19.3	0.1	0.2	0.2	3.9	0.2	6.7	0.1	0.2	6.2	0.2	47.0	11.1	9.3	16.4	0.1	0.0	0.1	26.2	0.5	0.2	12.0	2.7	0.3	2.1	1.0	2.1	0.0	1.7	0.1	0.6	0.0	1.6	0.3	3.5	0.8	0.1	41.8	14.1	30.8	8.1	12.0	18.2	1.2	0.0	0.7	8.8	0.5	38.7	0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	1.0	0.0	0.0	0.0	0.0	0.0	9.7	15.0	0.9	17.3	13.6	0.0	0.7	0.4	0.0	1.4	1.6	10.3	11.1	19.2	10.0	882.1	0.0	3.6	8.4	0.2	0.0	5.0	3.8	3.8	3.4	0.0	7.5	0.0	0.0	0.1	0.0	0.2	0.0	4.2	10.4	4.2	8.2	5.6	16.4	0.0	1473.6	1.6	0.1	18.7	0.5	10.3	11.4	0.8	3.9	0.0	7.3	50.5	753.8	0.0	0.0	0.0	3.7	4.7	23.9	1.4	12.4	534.0	0.1	18.3	0.0	786.1	144.1	19.2	0.0	7.5	1.2	18.0	0.0	0.3	8.7	2.0	0.0	28.8	5.3	0.3	0.8	0.2	1.4	0.3	1.3	73.7	0.0	2.9
NRAS	N-ras	ENSG00000213281	"NRAS proto-oncogene, GTPase"	P01111	1	114704469-114716771	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins"		Hydrolase	"Cancer-related genes, Disease variant, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB010157, HPA049830, CAB079912"	Uncertain		Supported	"Plasma membrane"		NA	NA			"Cluster 38: Basophils - Unknown function"	"Cluster 53: Non-specific - Cell cycle regulation"	"Cluster 40: Non-specific - Basic cellular processes"	"Cluster 16: Pancreatic endocrine cells - Mixed function"	"Plasma membrane"		"CAB010157: AB_632073, CAB079912: AB_2784586, HPA049830: AB_2680903"	"unprognostic (4.75e-2)"	"unprognostic (2.81e-1)"	"unprognostic (1.09e-3)"	"unprognostic (2.11e-2)"	"unprognostic (8.59e-3)"	"unprognostic (1.14e-1)"	"prognostic unfavorable (3.03e-7)"	"unprognostic (7.76e-3)"	"unprognostic (1.57e-2)"	"unprognostic (1.01e-3)"	"prognostic unfavorable (1.36e-4)"	"unprognostic (6.60e-3)"	"prognostic unfavorable (7.87e-4)"	"unprognostic (2.68e-1)"	"unprognostic (1.30e-1)"	"unprognostic (1.16e-1)"	"unprognostic (3.33e-2)"	19.0	9.1	10.3	25.7	11.2	58.5	18.0	11.5	12.3	12.5	8.6	27.8	21.5	12.4	7.8	20.7	10.3	17.2	8.3	10.2	12.2	20.9	24.9	18.5	30.4	12.3	12.1	9.6	11.4	9.0	4.3	28.3	12.3	11.4	26.6	6.6	10.9	7.1	7.7	19.8	22.5	14.1	11.7	18.6	21.8	9.6	11.4	39.0	16.1	7.8	29.7	22.2	8.6	13.4	93.7	24.9	65.2	24.9	26.4	56.3	46.5	43.5	48.4	79.5	89.0	50.4	33.9	70.4	56.3	58.9	55.4	26.0	88.2	70.6	113.4	96.5	34.2	47.8	34.5	60.2	52.3	120.0	71.0	51.1	56.1	91.5	66.2	25.0	102.8	54.6	77.3	78.5	71.0	248.9	83.5	46.4	111.0	30.2	17.9	62.9	116.0	44.1	70.6	49.5	39.4	59.0	44.7	36.4	107.1	75.4	31.9	96.2	79.2	43.3	82.2	81.5	90.3	137.7	101.6	81.6	86.4	64.6	159.0	38.7	12.8	12.6	11.7	19.2	10.5	12.8	9.3	11.6	12.6	10.5	9.9	12.9	3.4	15.5	17.6	9.6	13.4	13.1	10.3	11.2	11.5	12.3	10.2	12.2	12.3	12.1	12.3	11.7	11.4	13.4	22.7	16.0	16.5	8.1	25.9	30.7	31.2	23.1	15.4	5.2	18.5	13.6	5.6	18.6	19.3	22.0	8.4	22.4	27.7	49.2	13.7	34.1	3.9	22.9	24.7	29.2	24.6	31.6	5.8	31.5	50.4	16.1	29.0	38.0	31.1	22.2	33.2	29.7	49.2	5.0	5.2	28.1	30.5	44.9	30.7	5.9	8.1	30.4	23.2	9.4	41.6	7.8	22.6	5.0	8.1	51.4	32.9	6.4	39.6	30.6	28.1	39.4	23.1	3.3	6.6	12.8	15.3	7.3	15.4	24.6	36.2	31.2	21.9	13.8	28.8	40.2
PTCH1	"BCNS, NBCCS, PTCH"	ENSG00000185920	"Patched 1"	Q13635	9	95442980-95517057	"Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters"		Receptor	"Cancer-related genes, Disease variant, Holoprosencephaly, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"cervix: 26.7"	"Cell type enhanced"	"Detected in many"		"Late spermatids: 237.5;Leydig cells: 191.0;Peritubular cells: 444.5"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"gdT-cell: 6.1"	"Lineage enriched"	"Detected in single"	9	"T-cells: 6.1"	"Cell line enhanced"	"Detected in many"		"NTERA-2: 29.6;WM-115: 71.0"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB013717, HPA075072"	Uncertain		Approved	"Golgi apparatus"		NA	NA			"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 57: Non-specific - Angiogenesis"	"Cluster 17: WM-115 - Nervous system development"	"Cluster 52: Non-specific - Transcription"	"Golgi apparatus"		"CAB013717: , HPA075072: AB_2686733"	"unprognostic (1.46e-1)"	"unprognostic (1.06e-1)"	"unprognostic (3.16e-1)"	"unprognostic (1.79e-2)"	"unprognostic (3.22e-2)"	"unprognostic (9.01e-2)"	"unprognostic (2.13e-1)"	"unprognostic (3.54e-3)"	"unprognostic (2.63e-1)"	"unprognostic (8.66e-3)"	"unprognostic (1.52e-2)"	"unprognostic (2.82e-1)"	"unprognostic (1.13e-6)"	"unprognostic (8.63e-2)"	"unprognostic (4.40e-2)"	"unprognostic (2.76e-1)"	"unprognostic (2.82e-1)"	3.0	3.5	9.5	4.0	11.6	0.7	2.8	24.6	5.6	26.7	2.7	11.3	8.1	15.6	2.7	2.9	7.1	8.1	2.9	4.7	17.8	4.6	2.2	5.5	2.2	16.0	12.7	5.0	6.4	2.5	2.1	3.8	8.0	6.8	12.3	8.3	7.5	4.0	3.0	3.2	11.6	2.4	7.0	3.3	12.5	14.5	24.0	2.1	4.7	4.8	3.0	7.2	2.9	4.5	10.1	4.7	20.3	12.9	3.0	5.0	11.4	1.9	1.7	2.2	1.4	4.9	4.8	8.0	3.3	3.8	4.4	22.3	11.7	1.6	1.4	7.9	7.8	0.0	4.8	2.3	2.7	0.2	4.2	4.7	2.4	2.2	1.4	4.3	4.2	3.5	7.3	9.1	1.0	1.9	0.1	3.2	29.6	7.2	1.8	0.0	15.5	4.2	1.6	1.5	13.8	7.0	7.1	6.8	2.9	18.8	1.8	2.1	1.1	2.6	12.9	13.6	1.5	18.0	16.8	5.3	3.8	3.9	71.0	0.0	0.0	0.0	6.1	0.0	3.3	0.7	1.1	2.5	0.0	0.2	1.9	2.2	0.0	0.3	0.0	0.0	1.2	1.7	9.5	11.6	24.6	5.6	4.7	17.8	16.0	12.7	8.0	7.0	24.0	4.5	6.0	0.0	6.4	49.0	3.0	4.0	2.7	3.0	4.6	20.3	3.5	4.6	5.9	25.8	2.7	0.0	41.7	3.0	11.8	2.0	5.9	3.5	88.4	12.2	89.8	5.4	21.7	0.4	15.2	4.2	1.9	27.2	1.1	11.0	1.3	2.6	6.4	2.9	0.8	20.2	10.7	11.0	4.1	0.9	1.2	237.5	191.0	1.4	12.4	4.7	0.8	55.6	54.6	39.7	20.5	2.4	3.1	444.5	3.1	4.9	3.1	1.6	5.5	13.4	39.5	4.8	9.4	4.4	35.5	3.0	4.4	1.4	6.5	71.7	4.7	1.4
PTEN	"BZS, MHAM, MMAC1, PTEN1, TEP1"	ENSG00000171862	"Phosphatase and tensin homolog"	P60484	10	87863625-87971930	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Apoptosis, Lipid metabolism, Neurogenesis"	"Hydrolase, Protein phosphatase"	"Autism spectrum disorder, Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"neutrophil: 60.5"	"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in many"			"Low region specificity"	"Detected in all"							"CAB004076, HPA031335"	Approved		Supported	Nucleoplasm,Cytosol	"Intracellular and membrane"	NA	NA			"Cluster 9: Neutrophils - Innate immune response"	"Cluster 82: Adipose tissue - ECM organization"	"Cluster 24: NB-4 - Immune response"	"Cluster 48: Smooth muscle cells - ECM organization"	Nucleoplasm	Cytosol	"CAB004076: AB_390810, HPA031335: AB_2797221"	"unprognostic (8.72e-2)"	"unprognostic (2.45e-1)"	"unprognostic (5.43e-1)"	"unprognostic (1.50e-2)"	"unprognostic (3.71e-2)"	"unprognostic (1.30e-1)"	"unprognostic (2.18e-1)"	"unprognostic (2.08e-1)"	"unprognostic (2.07e-1)"	"unprognostic (6.87e-2)"	"unprognostic (9.77e-2)"	"unprognostic (2.71e-1)"	"prognostic unfavorable (7.35e-4)"	"unprognostic (1.57e-1)"	"unprognostic (2.73e-1)"	"unprognostic (6.54e-3)"	"unprognostic (2.41e-1)"	64.0	25.4	17.8	18.6	19.3	12.9	47.6	34.5	23.4	54.8	15.6	28.1	12.9	27.4	18.6	28.3	35.2	15.6	29.7	20.4	18.4	22.6	39.2	39.5	21.4	16.6	17.8	28.0	33.2	11.9	17.3	30.5	16.4	26.3	14.6	30.0	19.6	16.5	23.7	25.9	24.5	22.2	14.5	40.0	25.6	28.2	19.7	31.8	26.1	14.0	16.5	28.1	38.4	17.6	23.5	10.8	12.3	11.2	28.5	19.7	10.9	12.5	28.0	14.5	20.4	10.9	28.0	28.1	8.0	20.9	8.3	14.1	16.6	14.3	22.8	14.1	4.7	9.3	28.5	13.8	30.1	31.9	15.3	13.5	38.7	18.0	23.7	60.3	20.8	17.7	7.0	72.6	13.5	18.1	17.8	56.3	4.6	19.9	0.0	27.6	6.4	20.8	22.9	13.4	4.5	19.9	16.6	7.9	23.0	9.7	21.9	45.2	17.9	44.6	10.8	18.3	10.1	23.9	32.9	30.7	14.6	29.2	2.9	21.3	14.2	25.8	6.8	21.8	7.2	7.9	7.2	6.6	10.3	6.8	8.3	8.3	60.5	8.9	15.6	8.2	7.0	4.5	17.8	19.3	34.5	23.4	20.4	18.4	16.6	17.8	16.4	14.5	19.7	17.6	67.2	35.3	63.3	83.6	48.3	56.1	57.4	31.5	47.3	113.0	49.4	41.9	46.5	57.2	31.2	29.5	39.6	25.8	64.4	57.7	33.2	24.7	70.1	40.0	114.5	56.0	31.2	52.0	141.0	30.0	62.2	79.3	39.8	33.6	25.4	39.6	53.9	64.1	35.0	45.4	132.4	44.7	12.2	206.1	97.2	92.1	56.8	105.2	62.2	196.8	101.5	61.6	44.3	139.2	95.7	30.6	39.7	54.5	39.3	45.1	50.1	38.0	31.2	61.2	92.1	66.4	170.7	33.5	25.4	45.2	60.1	57.3	46.3	44.7	46.1	64.0
SHH	"HHG1, HLP3, HPE3, MCOPCB5, SMMCI, TPT, TPTPS"	ENSG00000164690	"Sonic hedgehog signaling molecule"	Q15465	7	155799980-155812463	"Disease related genes, Human disease related genes, Predicted intracellular proteins"		"Developmental protein, Hydrolase, Protease"	"Disease variant, Holoprosencephaly, Microphthalmia"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"liver: 13.6;stomach 1: 10.5;urinary bladder: 16.2"	"Cell type enhanced"	"Detected in some"		"Basal prostatic cells: 8.3;Cholangiocytes: 18.6;Collecting duct cells: 9.2;Gastric mucus-secreting cells: 9.7;Hepatocytes: 20.1;Intestinal goblet cells: 8.6;Pancreatic endocrine cells: 11.7;Urothelial cells: 8.3"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"EFO-21: 8.9;GAMG: 39.8;OE19: 10.2;RT4: 25.7"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in many"								"Intracellular and membrane"	NA	NA		5500000		"Cluster 85: Liver - Metabolism"	"Cluster 4: Mesenchymal cell lines - Antiviral immune response"	"Cluster 22: Epithelial cell types - Mixed function"				"unprognostic (7.17e-2)"	"unprognostic (7.68e-3)"	"unprognostic (6.70e-2)"	"prognostic favorable (8.62e-5)"	"unprognostic (1.59e-1)"	"unprognostic (2.50e-2)"	"unprognostic (2.39e-3)"	"unprognostic (1.82e-2)"	"unprognostic (1.83e-1)"	"unprognostic (2.16e-2)"	"unprognostic (3.47e-1)"	"unprognostic (1.56e-1)"	"unprognostic (1.77e-3)"	"unprognostic (2.86e-1)"	"unprognostic (2.85e-1)"	"unprognostic (3.43e-2)"	"unprognostic (2.66e-2)"	0.0	8.7	1.3	0.3	1.2	0.0	0.0	1.6	1.2	4.4	0.3	1.3	1.4	0.4	3.0	0.0	0.1	3.8	0.0	0.8	6.2	3.3	13.6	1.7	0.0	3.3	1.6	0.0	0.2	0.0	0.1	0.0	4.6	1.2	1.0	0.3	0.0	1.2	0.0	0.1	1.4	0.0	1.0	0.0	10.5	0.1	2.6	0.0	0.0	0.0	0.0	16.2	0.3	1.6	0.0	1.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.7	5.2	0.0	8.9	0.0	39.8	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	3.9	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.3	0.1	10.2	4.0	0.0	0.0	0.0	2.0	25.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.1	2.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.1	0.0	0.0	1.3	1.2	1.6	1.2	0.8	6.2	3.3	1.6	4.6	1.0	2.6	1.6	0.0	3.2	7.8	0.0	0.0	0.0	8.3	0.0	0.0	1.5	0.0	0.0	0.7	18.6	1.3	9.2	0.0	0.0	0.0	3.7	0.0	1.2	4.7	5.4	0.5	0.2	0.0	0.0	0.1	0.8	0.2	0.1	9.7	7.6	0.0	0.0	0.4	20.1	0.0	0.0	0.4	8.6	0.0	0.6	0.0	1.7	0.0	0.2	0.0	0.0	0.0	0.1	0.0	0.0	0.0	11.7	0.5	0.4	0.1	1.3	2.5	6.6	0.0	0.1	0.0	0.0	0.1	2.7	0.2	0.0	0.0	0.0	0.0	0.0	3.0	8.3
SMO	"FZD11, SMOH"	ENSG00000128602	"Smoothened, frizzled class receptor"	Q99835	7	129188633-129213545	"Cancer-related genes, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters"		"Developmental protein, G-protein coupled receptor, Receptor, Transducer"	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Astrocytes: 27.4;Granulosa cells: 13.0;Leydig cells: 20.8;Muller glia cells: 16.6;Peritubular cells: 21.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"AF22: 45.3;AN3-CA: 84.9;NTERA-2: 64.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB011446	Approved					NA	NA				"Cluster 15: Liver - Metabolism"	"Cluster 23: AN3-CA - Transcription regulation"	"Cluster 36: Stromal cells - Cell proliferation"			"CAB011446: "	"unprognostic (2.48e-2)"	"unprognostic (2.69e-2)"	"unprognostic (7.09e-2)"	"unprognostic (1.10e-1)"	"unprognostic (8.16e-2)"	"unprognostic (2.02e-1)"	"unprognostic (3.63e-1)"	"unprognostic (5.89e-2)"	"unprognostic (5.38e-3)"	"unprognostic (1.59e-1)"	"unprognostic (1.17e-2)"	"unprognostic (8.74e-3)"	"unprognostic (1.62e-1)"	"unprognostic (5.15e-3)"	"unprognostic (2.09e-1)"	"unprognostic (2.25e-1)"	"unprognostic (2.61e-2)"	5.2	6.0	9.4	2.6	10.8	0.4	5.5	9.9	9.6	27.4	18.4	9.6	2.5	19.2	18.6	12.0	14.5	8.4	8.0	8.9	10.0	19.0	23.9	3.6	2.2	12.4	12.4	28.3	6.3	16.1	19.2	2.6	9.9	20.0	2.1	2.0	11.5	12.3	3.7	17.1	5.7	8.1	11.8	2.8	6.3	5.6	11.4	4.4	9.1	3.7	2.0	9.0	16.7	9.7	1.6	18.2	45.3	84.9	1.1	0.2	14.3	5.2	6.7	10.1	5.8	13.8	0.1	0.0	13.9	10.4	22.8	28.3	27.4	1.5	3.9	0.0	23.0	9.4	0.0	22.5	5.5	0.4	0.0	16.2	11.0	3.3	0.0	19.9	5.8	24.9	1.5	0.0	3.1	0.0	24.4	0.1	64.2	0.0	5.3	35.1	19.7	0.0	5.2	0.0	1.3	30.2	0.0	0.0	12.3	16.8	11.1	5.8	0.0	0.7	14.1	17.6	10.1	0.6	0.0	0.0	0.0	0.0	16.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	9.4	10.8	9.9	9.6	8.9	10.0	12.4	12.4	9.9	11.8	11.4	9.7	0.4	0.0	0.0	27.4	0.2	1.9	2.3	3.9	2.8	0.7	3.3	5.2	1.4	2.8	3.8	11.0	0.0	0.3	0.4	0.0	1.9	3.4	0.4	1.0	8.6	0.6	0.0	0.0	1.4	1.1	0.3	7.6	0.0	1.3	0.0	13.0	1.4	8.4	4.2	0.0	0.8	0.1	2.0	1.6	1.8	1.3	20.8	1.0	0.0	3.7	0.6	16.6	0.0	4.5	0.5	1.3	0.1	21.8	0.0	2.7	0.0	3.9	0.7	0.4	6.6	3.5	3.9	0.0	2.0	3.3	2.8	0.5	0.1	6.9	0.6	0.7
TP53	"LFS1, p53"	ENSG00000141510	"Tumor protein p53"	P04637	17	7661779-7687538	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters"	"Apoptosis, Biological rhythms, Cell cycle, Host-virus interaction, Necrosis, Transcription, Transcription regulation"	"Activator, DNA-binding, Repressor"	"Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002973, CAB039238, CAB039239, HPA051244, HPA063532, CAB072876, CAB079965"	Enhanced		Supported	Nucleoplasm,Mitochondria,Cytosol		Yes	No			"Cluster 39: Non-specific - mRNA processing"	"Cluster 3: T-cells - Adaptive immune response"	"Cluster 14: REH - Unknown function"	"Cluster 32: Non-specific - Translation"	Nucleoplasm	"Mitochondria, Cytosol"	"CAB002973: AB_2206626, CAB039238: , CAB039239: , CAB072876: AB_2665731, CAB079965: , HPA051244: AB_2681403, HPA063532: "	"unprognostic (2.29e-2)"	"unprognostic (8.83e-3)"	"unprognostic (1.26e-2)"	"prognostic favorable (1.35e-4)"	"unprognostic (9.95e-2)"	"unprognostic (4.00e-2)"	"unprognostic (2.79e-3)"	"unprognostic (4.99e-2)"	"unprognostic (2.75e-2)"	"unprognostic (2.55e-1)"	"unprognostic (1.30e-1)"	"prognostic unfavorable (5.01e-4)"	"unprognostic (1.86e-3)"	"unprognostic (7.89e-3)"	"unprognostic (8.05e-2)"	"unprognostic (2.74e-1)"	"unprognostic (1.08e-1)"	19.3	13.8	10.4	27.1	12.6	19.6	22.5	10.4	16.5	19.9	10.3	29.0	18.9	24.5	12.8	28.8	31.3	13.2	11.1	10.1	11.4	14.9	16.5	15.1	34.6	18.7	13.6	27.3	18.3	9.4	7.3	23.5	12.5	17.7	27.5	4.1	18.9	15.3	12.3	37.4	20.4	24.6	12.6	31.1	22.6	10.4	12.3	47.2	17.4	6.1	45.4	20.8	19.9	13.3	81.5	145.3	81.1	57.3	37.3	43.9	82.8	28.4	66.1	78.5	100.2	4.2	40.6	190.5	126.9	58.7	77.6	174.9	119.7	80.4	72.8	42.7	76.5	77.6	76.8	70.9	111.5	1.6	37.0	55.7	93.0	38.9	106.5	45.6	79.4	24.7	3.8	6.9	41.5	145.1	130.0	96.3	80.2	10.4	2.4	252.2	56.1	66.2	59.4	87.3	46.0	80.5	94.1	62.6	24.3	39.4	109.2	7.4	100.7	91.6	30.2	1.0	48.3	47.6	37.9	82.5	23.6	9.7	80.1	1.2	21.2	3.4	13.0	21.7	15.9	21.5	13.3	14.6	30.3	19.1	13.7	15.4	2.4	17.5	19.3	27.3	17.3	14.7	10.4	12.6	10.4	16.5	10.1	11.4	18.7	13.6	12.5	12.6	12.3	13.3	21.1	9.6	12.8	16.3	26.0	28.7	14.5	24.6	24.5	2.6	36.1	30.4	2.5	18.6	15.4	20.2	0.0	36.9	24.7	16.9	9.8	24.8	12.8	11.5	29.0	24.5	30.7	21.7	2.1	18.1	39.6	17.0	11.2	19.5	1.3	31.7	22.1	18.0	24.2	0.0	3.2	43.0	18.3	27.8	20.1	3.8	23.0	19.3	12.4	7.5	31.9	4.9	25.7	9.0	8.0	15.8	16.4	17.0	7.8	15.7	10.3	10.1	8.8	2.6	13.1	25.9	20.6	0.5	4.9	28.7	32.8	22.4	16.5	27.4	54.1	11.5