Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ACD "Pip1, Ptop, Tint1, Tpp1" ENSG00000102977 "ACD shelterin complex subunit and telomerase recruitment factor" Q96AP0 16 67657512-67660815 "Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 71.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049411, HPA057660" Approved Enhanced "Nuclear bodies" NA Yes "Cluster 6: Non-specific - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nuclear bodies" "HPA049411: AB_2680752, HPA057660: AB_2683493" "unprognostic (1.47e-1)" "unprognostic (3.77e-2)" "unprognostic (1.09e-2)" "unprognostic (7.15e-3)" "unprognostic (2.22e-1)" "unprognostic (4.24e-3)" "prognostic unfavorable (2.42e-6)" "unprognostic (1.50e-2)" "unprognostic (4.75e-2)" "unprognostic (2.02e-1)" "unprognostic (1.13e-3)" "unprognostic (3.27e-2)" "unprognostic (8.88e-2)" "unprognostic (6.34e-2)" "unprognostic (2.00e-1)" "unprognostic (1.18e-1)" "unprognostic (3.30e-1)" 13.0 9.9 14.2 7.3 14.4 10.1 12.9 14.4 17.7 17.1 12.0 14.8 4.2 16.4 4.0 9.1 15.6 5.2 11.2 14.6 14.2 10.8 6.7 9.9 10.1 14.6 14.2 19.9 12.4 6.3 13.7 4.7 15.0 12.2 2.3 2.7 9.4 6.3 9.8 11.4 12.1 4.6 14.1 14.9 11.2 23.7 14.6 5.5 10.0 3.2 5.6 15.5 12.2 14.6 42.1 32.3 18.4 19.2 8.3 5.8 39.5 17.1 11.3 25.0 30.3 42.0 20.3 11.6 19.4 9.4 22.5 32.7 11.3 32.8 8.2 12.6 37.4 24.9 13.4 42.4 5.8 32.5 37.6 8.3 10.0 33.7 17.7 9.4 15.9 34.3 15.7 8.1 12.6 45.2 31.8 31.8 23.5 16.3 21.5 44.1 19.8 48.0 10.5 16.6 26.3 23.1 64.0 6.7 14.5 5.3 15.8 17.9 13.8 26.6 22.4 31.9 26.1 21.7 28.6 35.9 24.7 20.5 23.3 34.5 18.2 22.8 40.2 22.2 34.1 46.4 36.7 34.8 21.0 37.7 28.5 30.3 25.9 43.5 25.8 22.9 39.5 24.7 14.2 14.4 14.4 17.7 14.6 14.2 14.6 14.2 15.0 14.1 14.6 14.6 19.4 6.4 11.9 5.5 22.3 14.4 15.9 22.6 21.6 14.7 13.7 16.0 2.8 8.6 12.6 11.0 4.2 25.1 22.5 5.5 9.8 21.3 59.3 6.6 7.7 15.4 12.5 11.6 6.2 19.6 22.8 14.1 9.7 6.8 27.9 13.6 12.8 4.7 15.5 13.5 6.1 6.4 6.1 7.6 20.6 71.4 15.2 13.4 23.2 4.7 19.3 14.3 30.9 4.0 3.6 18.4 9.2 11.7 17.0 9.9 10.2 13.2 16.1 10.8 6.6 11.8 14.8 58.1 24.1 7.1 9.7 11.4 27.0 6.9 9.0 10.0 AK4 "AK3, AK3L1" ENSG00000162433 "Adenylate kinase 4" P27144 1 65147549-65232145 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 183.5;liver: 104.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 242.6;Proximal tubular cells: 595.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.1;myeloid DC: 2.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 208.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042753, HPA049461" Enhanced Supported Mitochondria "Intracellular and membrane" NA Yes 39000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA042753: AB_2678146, HPA049461: AB_2680776" "unprognostic (3.73e-2)" "prognostic unfavorable (4.17e-4)" "unprognostic (2.25e-1)" "unprognostic (3.05e-3)" "unprognostic (1.48e-2)" "prognostic unfavorable (8.83e-4)" "unprognostic (1.16e-3)" "unprognostic (3.89e-2)" "unprognostic (4.03e-1)" "unprognostic (5.39e-2)" "prognostic unfavorable (4.34e-5)" "unprognostic (6.71e-2)" "prognostic unfavorable (4.36e-4)" "prognostic unfavorable (4.87e-4)" "unprognostic (2.69e-1)" "unprognostic (7.07e-2)" "unprognostic (7.57e-2)" 24.7 1.9 19.5 6.6 21.0 4.9 26.6 17.8 20.8 6.1 17.5 19.7 4.3 7.0 4.2 23.4 7.6 13.7 51.7 21.4 21.2 183.5 104.0 2.8 1.6 19.0 22.8 4.6 1.2 18.3 4.7 8.3 22.8 16.2 14.0 21.9 9.6 12.7 1.7 27.4 6.6 21.4 18.5 1.2 15.0 11.3 22.7 5.7 2.5 38.8 3.3 19.1 11.8 21.1 73.2 5.0 5.6 23.9 51.6 48.7 12.0 12.1 15.0 25.6 70.8 108.1 8.6 39.1 31.0 19.0 32.1 46.1 18.8 89.9 101.9 33.0 21.5 37.9 21.9 208.6 2.5 29.9 4.6 27.2 49.6 25.1 73.0 42.2 0.9 12.2 48.0 0.6 39.6 31.2 1.1 1.3 24.6 1.0 42.5 0.2 41.0 7.1 37.8 3.2 20.5 15.4 21.6 1.5 16.7 25.8 29.7 12.9 4.2 42.4 36.2 3.3 20.9 39.5 18.8 2.1 68.7 10.9 2.5 0.9 3.1 0.0 0.1 0.6 0.2 0.2 0.1 0.2 2.7 0.1 0.1 0.1 0.4 0.3 0.1 0.4 0.0 0.8 19.5 21.0 17.8 20.8 21.4 21.2 19.0 22.8 22.8 18.5 22.7 21.1 11.2 0.0 0.5 51.2 4.7 49.7 23.6 44.2 63.7 24.5 48.9 44.7 105.7 52.9 14.3 31.3 2.1 2.2 0.6 15.8 56.7 18.6 3.4 30.1 8.2 19.6 5.4 13.9 17.1 12.1 21.1 11.4 27.5 52.2 0.0 36.4 11.7 242.6 3.3 16.8 7.7 8.7 24.4 7.8 9.2 5.8 4.1 6.9 24.9 3.7 5.7 32.7 0.0 9.5 2.5 31.9 4.3 9.4 0.4 38.7 18.8 595.5 12.3 6.5 6.6 5.6 18.8 1.8 9.5 43.1 74.3 4.9 3.6 0.7 23.1 20.4 AL031777.2 ENSG00000282988 "Novel protein" 6 26195595-26199293 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 5.1;Extravillous trophoblasts: 6.7;Hofbauer cells: 9.1;Syncytiotrophoblasts: 20.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 16.9;neutrophil: 30.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 30.6" "Cell line enhanced" "Detected in some" "K-562: 6.9;SiHa: 7.7;T-47d: 4.6;U-2 OS: 5.1;U-266/70: 9.3;U-266/84: 5.6" HPA041189 Uncertain Approved Nucleoplasm NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 16: U-266 - Nucleosome" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "HPA041189: AB_2677357" 0.6 0.3 0.5 0.2 0.6 1.5 1.1 1.3 1.2 2.0 1.6 0.7 0.3 0.1 0.0 3.4 0.4 0.1 0.4 0.6 0.5 0.8 1.9 2.2 0.3 1.2 0.8 0.4 0.1 0.1 0.3 0.3 1.1 2.5 0.3 0.1 0.5 0.0 0.0 0.8 0.6 0.1 1.0 2.0 0.5 0.7 1.0 0.8 0.4 0.0 0.1 0.4 2.4 1.4 0.2 0.7 0.2 0.7 1.5 0.1 0.5 0.6 0.1 1.2 0.4 0.2 0.5 0.1 2.0 0.1 0.5 1.4 0.1 0.0 0.2 2.6 0.2 0.4 2.1 0.3 0.1 0.1 0.9 1.0 0.0 0.1 0.3 0.2 0.0 0.6 6.9 1.5 0.0 1.0 0.1 0.4 0.2 2.6 1.6 0.2 0.1 3.0 0.0 0.0 0.6 0.2 7.7 0.5 0.3 0.3 4.6 0.0 0.0 0.7 5.1 0.0 0.0 9.3 5.6 0.7 0.0 1.9 0.7 16.9 0.6 5.1 1.6 0.7 3.6 2.1 0.8 1.1 2.3 4.7 0.8 0.5 30.6 0.9 1.5 5.2 2.3 1.1 0.5 0.6 1.3 1.2 0.6 0.5 1.2 0.8 1.1 1.0 1.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.7 0.0 0.0 0.0 0.0 AP1S1 "AP19, CLAPS1, EKV3, SIGMA1A, WUGSC:H_DJ0747G18.2" ENSG00000106367 "Adaptor related protein complex 1 subunit sigma 1" P61966 7 101154456-101161596 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Deafness, Ichthyosis, Mental retardation, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 344.4;Proximal enterocytes: 241.3;Proximal tubular cells: 304.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060945 Supported Supported "Golgi apparatus,Vesicles" NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus, Vesicles" "HPA060945: AB_2684393" "unprognostic (1.98e-2)" "unprognostic (5.41e-3)" "unprognostic (1.02e-1)" "unprognostic (3.34e-2)" "unprognostic (2.98e-3)" "unprognostic (8.70e-3)" "unprognostic (7.06e-3)" "unprognostic (1.12e-1)" "unprognostic (1.76e-1)" "unprognostic (7.79e-2)" "unprognostic (1.34e-1)" "unprognostic (3.75e-2)" "unprognostic (2.81e-2)" "unprognostic (2.14e-2)" "unprognostic (1.74e-1)" "unprognostic (1.49e-1)" "unprognostic (2.75e-1)" 14.4 24.6 72.2 13.9 75.7 5.8 17.2 43.7 82.6 18.3 34.6 28.6 39.0 16.9 17.0 34.2 13.8 12.8 11.8 85.2 59.6 41.2 36.2 14.7 11.9 53.6 51.9 13.5 21.9 22.8 31.0 15.9 53.4 22.2 22.4 14.6 20.3 9.3 6.4 39.2 30.3 12.7 46.1 20.2 22.0 16.4 62.5 19.1 15.2 8.5 13.6 20.1 19.5 62.7 121.0 87.3 63.3 118.4 42.8 70.4 138.2 76.8 51.1 50.8 52.8 47.3 147.5 24.9 127.5 84.6 97.1 59.0 35.3 116.0 45.6 57.0 56.6 16.8 52.0 61.4 54.2 46.8 87.7 79.1 91.0 49.4 20.6 76.7 76.8 54.1 56.7 103.2 129.9 292.1 40.4 107.8 97.8 177.0 188.2 24.9 27.2 54.6 127.8 88.8 47.5 157.7 40.4 121.1 151.4 101.6 50.7 46.8 79.0 74.1 132.3 27.6 55.2 21.4 51.4 48.4 195.2 50.1 152.9 0.5 3.3 0.3 2.3 3.1 2.2 2.6 3.2 2.5 4.6 2.0 1.9 1.8 1.2 1.3 1.8 5.0 3.3 2.4 72.2 75.7 43.7 82.6 85.2 59.6 53.6 51.9 53.4 46.1 62.5 62.7 34.4 6.4 0.0 2.3 17.9 38.7 29.7 173.0 46.7 30.7 54.8 49.0 1.1 45.8 72.9 55.2 8.4 170.7 19.8 88.4 344.4 128.2 2.5 28.8 34.2 36.7 90.3 16.2 21.2 111.7 101.3 27.7 42.8 31.9 5.7 85.3 28.9 43.0 95.2 30.3 10.3 96.5 116.0 24.8 21.6 3.4 35.1 27.3 53.4 7.5 58.0 34.1 17.5 2.5 9.8 183.3 86.1 21.8 17.4 34.9 241.3 304.8 34.9 22.3 19.7 11.4 38.4 13.1 70.9 51.4 45.5 60.5 19.5 157.4 119.9 38.2 APEX2 "APE2, APEXL2, XTH2, ZGRF2" ENSG00000169188 "Apurinic/apyrimidinic endodeoxyribonuclease 2" Q9UBZ4 X 55000363-55009057 "Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair" "DNA-binding, Endonuclease, Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 52.7;Syncytiotrophoblasts: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048577 Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nucleoli fibrillar center" Vesicles "HPA048577: AB_2680448" "unprognostic (2.90e-2)" "prognostic favorable (6.17e-4)" "unprognostic (4.32e-2)" "unprognostic (2.39e-1)" "unprognostic (1.62e-1)" "unprognostic (5.62e-2)" "prognostic unfavorable (6.13e-7)" "unprognostic (5.89e-2)" "unprognostic (4.87e-2)" "prognostic favorable (5.21e-4)" "unprognostic (7.46e-2)" "unprognostic (3.16e-1)" "unprognostic (6.86e-2)" "unprognostic (1.03e-2)" "unprognostic (3.17e-2)" "unprognostic (1.40e-1)" "prognostic favorable (6.63e-4)" 7.2 8.9 6.1 8.8 6.3 10.0 7.2 6.0 6.6 7.6 6.5 8.9 8.9 7.4 8.5 15.5 7.3 6.3 9.0 5.9 6.4 10.8 11.0 7.2 11.3 6.4 6.3 9.6 7.4 7.1 7.0 9.0 6.3 7.8 10.5 2.3 7.0 6.6 7.5 12.2 9.1 7.0 6.3 11.2 7.9 4.1 6.6 10.9 6.3 7.3 13.5 10.2 9.4 6.7 36.9 32.4 12.5 18.3 17.9 11.9 21.3 14.8 19.8 28.0 27.2 17.8 30.0 24.1 22.7 14.0 33.0 26.9 29.1 28.2 21.0 19.7 22.1 29.4 31.6 18.3 11.5 18.3 26.6 11.8 22.6 39.6 14.2 13.2 22.6 25.3 15.4 15.9 21.2 35.7 24.9 23.8 25.0 17.4 38.6 21.8 20.8 26.4 15.2 18.1 11.6 12.7 28.0 33.4 14.7 28.5 26.4 14.1 13.1 16.6 23.9 33.7 19.6 16.4 22.9 19.9 17.7 30.9 20.1 16.2 11.5 13.1 10.2 14.4 8.6 8.2 9.6 10.2 13.7 8.5 8.5 8.4 4.1 42.0 13.4 7.4 11.6 10.1 6.1 6.3 6.0 6.6 5.9 6.4 6.4 6.3 6.3 6.3 6.6 6.7 6.1 3.2 11.8 1.6 12.7 12.9 12.5 20.1 6.8 3.6 7.2 7.1 5.9 15.7 14.9 11.0 0.0 52.7 7.1 17.9 15.6 31.5 0.3 6.0 5.7 11.5 6.1 31.5 0.8 15.1 35.3 7.6 10.2 9.7 8.8 13.1 10.4 11.4 24.2 6.7 0.7 10.1 10.2 10.9 11.1 1.1 5.9 12.0 0.0 1.9 21.7 5.2 16.5 1.0 1.9 20.5 19.1 8.6 9.8 10.5 16.6 21.6 11.8 2.1 19.7 4.4 6.9 1.4 10.6 13.8 12.6 47.6 11.6 12.4 13.7 13.2 ARL6IP6 MGC33864 ENSG00000177917 "ADP ribosylation factor like GTPase 6 interacting protein 6" Q8N6S5 2 152717893-152762396 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 155.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 214.0;eosinophil: 161.8" "Lineage enriched" "Detected in all" 9 "granulocytes: 214.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014743 Approved Approved "Nuclear membrane,Cytosol" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear membrane" Cytosol "HPA014743: AB_1845030" "unprognostic (4.41e-1)" "unprognostic (6.52e-2)" "unprognostic (1.31e-1)" "unprognostic (9.81e-3)" "unprognostic (1.28e-1)" "unprognostic (9.86e-3)" "prognostic unfavorable (1.73e-4)" "unprognostic (5.43e-2)" "unprognostic (2.07e-2)" "unprognostic (2.00e-3)" "unprognostic (4.95e-2)" "unprognostic (1.88e-1)" "prognostic unfavorable (2.14e-4)" "unprognostic (2.14e-1)" "unprognostic (2.67e-1)" "unprognostic (4.57e-1)" "unprognostic (7.39e-2)" 5.1 3.9 3.0 1.8 4.0 8.3 4.7 3.2 3.0 4.4 2.2 3.7 2.4 4.2 1.2 6.0 3.8 1.2 2.7 2.6 3.1 2.5 1.9 4.0 3.4 3.9 3.3 5.0 2.7 1.1 3.1 4.4 4.3 3.1 1.9 3.2 3.9 1.8 3.5 7.1 3.5 1.6 3.6 4.4 3.1 5.3 3.3 3.9 3.2 2.0 2.4 4.2 5.5 5.3 9.6 6.2 13.7 3.9 4.1 4.6 19.7 11.6 4.9 9.6 12.2 14.2 13.3 17.2 10.6 5.2 4.3 10.7 8.1 5.7 10.4 26.1 15.1 14.2 5.3 13.0 4.5 12.1 12.4 3.3 6.5 10.6 8.9 3.4 7.5 11.9 14.9 10.6 7.8 7.1 12.1 12.6 13.3 3.2 12.7 13.0 13.4 13.9 4.5 7.2 11.6 12.0 10.4 1.1 9.7 4.7 4.7 7.9 10.0 14.4 9.9 10.2 10.3 9.9 10.3 13.1 6.8 10.4 12.3 214.0 9.1 161.8 13.2 10.2 13.2 20.3 13.3 13.5 10.9 18.4 13.6 11.4 24.8 9.7 12.8 24.8 19.7 13.2 3.0 4.0 3.2 3.0 2.6 3.1 3.9 3.3 4.3 3.6 3.3 5.3 34.3 16.0 10.0 30.7 41.9 106.6 48.5 74.0 50.7 6.3 20.3 14.9 4.3 17.2 29.9 11.0 4.2 155.7 42.4 14.1 17.6 24.9 14.1 17.7 20.0 31.3 13.8 81.0 21.0 18.6 136.2 27.9 30.1 25.0 27.3 19.4 28.5 5.9 39.8 8.4 23.8 22.2 38.7 24.2 57.2 24.2 19.6 33.6 46.2 30.9 46.2 19.8 32.0 38.7 56.8 22.5 18.6 17.0 33.8 40.3 16.3 8.8 29.2 15.8 32.9 22.2 24.9 24.4 30.0 43.4 106.6 108.4 45.2 27.9 24.5 51.3 ARRDC3 "KIAA1376, TLIMP" ENSG00000113369 "Arrestin domain containing 3" Q96B67 5 91368631-91383317 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 394.2;Syncytiotrophoblasts: 339.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 115.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 20: HeLa - Mitochondria" "Cluster 41: Macrophages - Immune response" "unprognostic (2.28e-1)" "unprognostic (2.24e-1)" "unprognostic (9.42e-2)" "unprognostic (1.28e-1)" "unprognostic (4.07e-2)" "unprognostic (7.36e-2)" "unprognostic (1.57e-3)" "unprognostic (4.91e-2)" "unprognostic (2.44e-1)" "prognostic unfavorable (3.30e-4)" "unprognostic (1.50e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.25e-8)" "prognostic unfavorable (2.26e-4)" "unprognostic (1.34e-1)" "unprognostic (5.74e-2)" "unprognostic (2.15e-1)" 36.8 80.1 16.9 26.8 22.6 167.4 94.6 23.7 32.5 44.8 24.0 19.9 9.9 40.5 27.1 38.7 24.9 39.0 24.7 16.3 20.1 52.7 75.9 44.5 29.3 27.8 20.2 93.2 20.8 54.3 21.5 76.8 22.3 30.3 27.5 75.1 63.9 24.3 34.2 41.3 16.8 33.0 23.8 37.1 25.7 16.6 18.1 28.0 84.0 44.9 28.2 57.0 42.0 41.9 6.6 10.7 12.1 16.6 18.4 31.0 40.2 15.8 14.7 9.3 16.2 5.2 26.9 7.9 13.0 16.2 26.1 14.6 13.4 13.3 8.5 8.2 1.4 3.9 43.3 8.5 14.3 27.9 1.6 13.3 21.2 8.1 20.9 56.4 26.1 7.6 11.5 37.7 14.4 3.7 29.9 4.1 4.3 2.8 11.3 24.8 15.2 41.5 60.4 11.9 21.1 14.0 48.2 3.7 2.9 30.2 17.9 13.1 28.3 7.7 11.2 12.4 9.6 28.6 40.9 16.1 45.8 16.4 8.7 28.7 15.2 20.4 29.1 13.1 21.1 12.3 18.3 22.8 9.3 9.4 24.0 37.7 115.3 14.9 22.2 2.2 21.9 19.9 16.9 22.6 23.7 32.5 16.3 20.1 27.8 20.2 22.3 23.8 18.1 41.9 53.8 51.3 166.5 6.5 47.0 112.0 17.6 51.2 9.1 30.9 89.5 48.5 34.5 20.0 72.4 97.5 31.3 89.9 110.2 21.2 154.6 72.6 27.1 28.9 43.1 143.3 73.0 37.1 10.5 79.5 81.6 95.7 38.7 51.4 37.3 36.4 37.5 155.1 48.7 32.0 15.5 32.4 10.2 106.9 394.2 22.3 21.1 100.3 120.9 14.0 56.6 97.0 50.4 13.6 28.3 41.2 16.1 15.1 58.8 31.2 9.3 57.3 28.5 67.2 19.7 32.1 54.9 8.1 9.6 55.6 118.3 339.4 66.3 23.4 20.2 22.7 ATAD2 "ANCCA, CT137, DKFZp667N1320, MGC29843, MGC5254, PRO2000" ENSG00000156802 "ATPase family AAA domain containing 2" Q6PL18 8 123319850-123416350 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 28.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 79.1;Spermatocytes: 106.0;Spermatogonia: 82.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 294.4" "Low region specificity" "Detected in all" "HPA029424, CAB056158" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 33: Neutrophils - Chromatin organization" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB056158: AB_2665580, HPA029424: AB_10611680" "unprognostic (1.56e-1)" "unprognostic (4.55e-2)" "unprognostic (2.07e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.08e-1)" "unprognostic (4.44e-2)" "unprognostic (2.98e-2)" "unprognostic (2.74e-3)" "unprognostic (2.02e-3)" "unprognostic (5.62e-2)" "unprognostic (1.19e-2)" "unprognostic (4.98e-2)" "prognostic unfavorable (8.33e-15)" "unprognostic (1.15e-2)" "unprognostic (1.82e-1)" "unprognostic (4.84e-2)" "unprognostic (6.17e-2)" 2.9 3.4 3.8 7.7 3.6 26.5 6.8 2.6 3.9 12.8 2.0 5.3 5.0 4.3 3.8 6.8 3.4 3.2 5.8 3.2 4.5 1.4 9.9 4.1 14.4 2.9 3.8 7.0 3.3 1.9 3.9 4.8 2.6 10.3 6.9 1.4 4.3 4.7 9.3 6.8 5.2 4.1 2.8 4.9 4.7 18.9 5.1 28.3 3.9 3.2 12.8 4.8 3.9 2.8 103.7 39.6 55.0 19.0 9.7 12.3 24.3 79.2 27.2 66.8 73.9 30.1 43.8 67.2 23.6 25.2 26.5 48.3 74.2 25.6 106.1 94.3 39.0 121.2 41.0 61.4 3.8 44.6 57.4 4.1 3.8 63.6 21.0 14.3 20.7 38.6 57.7 66.4 50.4 107.1 129.5 32.8 10.0 77.8 38.4 66.5 65.6 36.4 23.8 46.7 70.2 30.5 114.4 294.4 20.8 22.1 60.2 41.2 13.0 50.4 69.3 40.2 96.6 21.2 40.7 60.8 32.9 72.9 40.4 5.3 0.8 3.3 1.6 0.8 2.2 2.6 2.3 2.7 1.4 1.5 1.5 1.7 0.2 2.5 1.9 0.1 4.6 1.0 3.8 3.6 2.6 3.9 3.2 4.5 2.9 3.8 2.6 2.8 5.1 2.8 4.8 6.4 11.0 9.4 18.5 15.8 27.9 9.1 14.2 2.8 17.3 21.2 27.3 2.8 10.2 3.7 4.2 14.9 15.3 9.0 1.9 3.5 54.9 7.9 17.3 9.6 1.2 79.1 25.6 2.2 26.2 17.1 13.3 17.5 14.5 37.9 7.1 16.3 11.2 1.7 16.4 13.1 4.1 8.2 6.9 24.4 7.5 11.7 1.8 14.0 6.3 6.3 17.5 11.6 2.8 3.5 4.3 13.9 34.0 20.7 3.1 1.0 5.4 1.9 0.0 9.5 17.5 106.0 82.4 23.7 12.1 13.5 22.8 3.7 14.6 24.5 ATF3 ENSG00000162772 "Activating transcription factor 3" P18847 1 212565334-212620777 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 1462.0;Endometrial ciliated cells: 1049.4;Glandular and luminal cells: 1429.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 6.4;intermediate monocyte: 4.0;myeloid DC: 1.6;non-classical monocyte: 6.3" "Group enriched" "Detected in many" 15 "dendritic cells: 1.6;granulocytes: 6.4;monocytes: 6.3" "Cell line enhanced" "Detected in many" "BEWO: 131.5;HDLM-2: 100.4;SuSa: 155.0" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 9.3" HPA001562 Approved Supported Nucleoplasm,Nucleoli Yes Yes "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nucleoli" "HPA001562: AB_1078233" "unprognostic (2.66e-2)" "unprognostic (1.52e-2)" "unprognostic (2.80e-1)" "unprognostic (4.27e-3)" "unprognostic (3.29e-1)" "unprognostic (1.46e-1)" "unprognostic (1.31e-1)" "unprognostic (1.73e-1)" "unprognostic (9.31e-2)" "unprognostic (8.65e-3)" "unprognostic (8.75e-2)" "unprognostic (1.52e-1)" "unprognostic (6.97e-2)" "unprognostic (3.31e-2)" "unprognostic (1.10e-1)" "unprognostic (2.04e-2)" "unprognostic (2.08e-2)" 176.1 82.8 14.2 63.3 17.7 45.3 97.6 16.5 18.7 106.2 17.1 66.6 21.0 108.6 9.3 128.4 122.6 135.0 113.7 14.4 20.2 98.1 139.9 116.0 20.8 21.1 16.7 40.2 67.2 48.8 45.0 66.3 17.2 116.3 60.0 16.2 33.1 24.1 30.7 154.9 45.6 313.0 15.4 24.4 104.8 3.9 18.8 84.5 181.1 30.0 3.1 281.2 55.2 25.0 21.1 1.2 40.7 8.7 3.9 10.4 131.5 14.7 11.9 12.5 29.8 27.7 15.5 0.4 6.5 0.9 68.0 11.6 24.6 4.0 20.5 100.4 24.6 1.6 11.6 10.0 72.9 9.0 22.7 18.3 65.3 34.9 80.4 2.4 2.6 23.9 10.0 77.0 1.9 2.8 27.5 5.9 29.2 11.5 9.2 8.1 27.1 18.4 1.8 3.0 18.3 18.4 19.1 34.2 59.0 155.0 19.9 6.5 2.4 3.6 19.5 12.3 6.7 60.4 27.9 7.4 11.9 4.8 10.8 6.4 0.7 0.0 0.3 4.0 0.3 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.2 0.0 6.3 0.8 0.0 0.7 14.2 17.7 16.5 18.7 14.4 20.2 21.1 16.7 17.2 15.4 18.8 25.0 568.2 423.1 146.5 1.6 55.3 202.8 866.2 236.1 1462.0 4.4 753.9 510.9 689.3 92.9 136.0 55.2 0.0 178.9 100.3 611.7 1.9 186.2 3.7 1049.4 318.2 176.2 889.6 2.7 2.6 122.7 330.8 452.6 966.9 1429.3 78.6 5.6 30.7 25.8 103.7 1.7 2.4 758.4 114.0 29.8 282.8 2.8 17.4 351.8 174.3 3.7 32.3 39.9 0.0 1.5 10.8 185.7 484.8 1.2 161.0 457.5 421.3 3.3 133.2 5.3 98.6 279.4 573.7 2.2 3.1 474.6 202.7 420.6 97.1 5.8 349.6 263.6 BARD1 ENSG00000138376 "BRCA1 associated RING domain 1" Q99728 2 214725646-214809683 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 68.6;Basal prostatic cells: 62.2;Suprabasal keratinocytes: 74.4;Urothelial cells: 67.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034106, HPA035354, HPA044864" Enhanced Supported "Nucleoplasm,Nuclear speckles,Cytoplasmic bodies" No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Nuclear speckles" "Cytoplasmic bodies" "CAB034106: AB_2061237, HPA035354: AB_2674585, HPA044864: AB_2679119" "unprognostic (4.85e-2)" "unprognostic (1.87e-2)" "unprognostic (1.74e-2)" "unprognostic (8.37e-3)" "unprognostic (2.57e-2)" "unprognostic (1.03e-2)" "unprognostic (6.25e-4)" "unprognostic (1.99e-1)" "unprognostic (2.16e-2)" "unprognostic (3.92e-3)" "unprognostic (2.80e-2)" "unprognostic (7.41e-2)" "unprognostic (1.94e-8)" "unprognostic (3.94e-2)" "unprognostic (2.28e-1)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" 1.8 0.6 3.0 2.7 4.6 11.4 2.9 2.2 2.7 3.1 0.2 2.9 2.3 3.3 2.6 5.1 1.9 2.0 1.5 2.3 4.1 0.8 1.0 2.5 5.5 3.8 3.2 2.3 1.6 2.3 1.2 2.3 3.9 2.9 3.6 2.0 1.9 3.6 4.2 8.8 2.1 3.9 3.9 2.6 1.9 6.6 4.1 7.0 1.4 2.3 6.6 2.1 3.8 4.2 12.3 8.8 20.2 9.3 2.7 4.0 12.0 17.3 10.6 17.8 21.8 12.0 12.2 12.6 7.6 8.5 9.5 12.7 16.5 10.5 22.7 11.5 6.4 12.5 13.8 8.7 0.9 13.9 12.7 4.7 1.1 15.0 8.1 4.5 6.1 14.7 7.9 36.0 13.7 10.7 27.9 12.5 14.3 7.9 3.7 24.7 19.8 11.2 3.9 14.0 5.8 8.8 15.0 14.7 5.3 10.9 16.3 13.4 4.7 18.0 14.0 11.7 13.6 10.2 12.6 28.0 7.6 11.3 13.4 3.9 2.0 5.8 4.6 4.0 3.2 9.7 5.4 5.5 3.6 8.2 2.4 4.0 0.3 7.3 3.8 6.9 17.1 2.3 3.0 4.6 2.2 2.7 2.3 4.1 3.8 3.2 3.9 3.9 4.1 4.2 12.3 6.4 2.2 14.7 13.0 68.6 62.2 13.0 14.2 3.3 9.9 14.1 17.4 17.2 12.7 9.2 0.0 18.2 11.3 8.2 3.9 8.0 9.2 13.3 11.9 9.6 1.2 34.5 5.5 6.9 16.0 10.0 10.2 18.0 15.2 28.2 10.0 4.2 12.5 1.7 15.4 13.1 8.2 10.1 12.2 5.7 6.2 11.2 3.6 15.9 16.6 4.4 9.2 19.6 31.7 6.5 6.5 10.1 22.0 22.9 3.2 0.7 12.3 6.8 19.7 15.4 16.9 27.6 43.4 28.6 74.4 5.1 13.4 10.5 14.7 67.2 BDNF ENSG00000176697 "Brain derived neurotrophic factor" P23560 11 27654893-27722058 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 38.5;Bipolar cells: 13.8;Cardiomyocytes: 9.1;Excitatory neurons: 22.3;Smooth muscle cells: 25.8;Theca cells: 9.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 36.6;BJ hTERT+ SV40 Large T+: 28.0;BJ hTERT+ SV40 Large T+ RasG12V: 20.9;HBF TERT88: 26.5;U-138 MG: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB009564, HPA031440, HPA056104" Enhanced Supported "Nuclear speckles,Mitochondria" "Secreted to blood" NA Yes 16000000 24000 "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Mitochondria" "CAB009564: AB_2064213, HPA031440: AB_2673883, HPA056104: AB_2683038" "unprognostic (1.25e-2)" "unprognostic (2.84e-1)" "unprognostic (4.35e-2)" "unprognostic (2.54e-2)" "unprognostic (1.01e-2)" "unprognostic (6.82e-2)" "unprognostic (2.39e-2)" "unprognostic (2.21e-1)" "unprognostic (3.20e-1)" "unprognostic (1.78e-1)" "unprognostic (1.22e-2)" "unprognostic (2.65e-1)" "unprognostic (3.22e-2)" "unprognostic (3.88e-2)" "unprognostic (5.88e-2)" "unprognostic (1.40e-1)" "unprognostic (2.84e-3)" 0.4 0.5 1.9 0.2 2.4 0.2 0.2 3.3 5.3 0.6 0.1 0.4 0.3 0.2 3.3 0.6 0.1 0.7 3.6 8.2 1.9 0.6 0.1 2.0 0.1 3.3 2.1 0.5 0.4 0.0 1.2 1.6 2.5 2.0 0.1 0.7 0.3 1.8 0.4 0.9 0.1 0.1 0.4 0.1 0.3 0.6 1.6 0.3 1.0 0.0 0.1 2.1 0.6 0.8 2.9 12.2 0.3 0.0 3.7 2.2 0.0 36.6 7.9 28.0 20.9 0.1 4.0 0.0 3.7 11.8 0.5 1.4 0.1 0.2 26.5 0.2 0.1 0.0 3.5 0.0 17.4 0.2 0.2 9.2 4.2 6.8 3.7 18.1 1.3 0.1 0.0 0.1 4.8 0.0 0.0 0.0 4.0 0.1 2.9 0.0 2.0 0.0 4.5 0.0 0.2 1.1 7.8 0.1 0.1 1.7 0.2 0.0 11.0 37.6 6.9 14.4 9.2 0.5 0.1 0.0 14.1 1.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.4 3.3 5.3 8.2 1.9 3.3 2.1 2.5 0.4 1.6 0.8 0.2 38.5 0.5 1.6 0.0 0.6 0.4 0.5 1.8 13.8 0.5 0.9 9.1 0.0 0.4 1.8 4.2 0.4 0.0 0.1 0.0 0.8 1.8 0.3 0.3 0.2 0.0 0.0 22.3 0.0 0.5 6.1 0.0 0.1 1.3 1.9 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.4 1.5 0.3 0.9 1.8 0.0 0.0 0.2 0.0 2.0 2.2 0.2 0.0 0.0 0.0 0.8 0.0 1.5 0.1 1.8 0.0 1.8 25.8 3.7 0.8 2.3 0.0 0.7 0.0 9.3 0.1 0.1 BIRC5 "API4, EPR-1, survivin" ENSG00000089685 "Baculoviral IAP repeat containing 5" O15392 17 78214186-78225636 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis, Transcription, Transcription regulation" "Protease inhibitor, Repressor, Thiol protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.9;lymphoid tissue: 41.0;testis: 19.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 74.7;Early spermatids: 94.1;Erythroid cells: 166.7;Extravillous trophoblasts: 162.0;Spermatocytes: 191.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 14.1" "Lineage enriched" "Detected in many" 6 "T-cells: 14.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002830, CAB004270" Enhanced Supported "Cytokinetic bridge" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Cytokinetic bridge" "CAB004270: AB_628302, HPA002830: AB_1857672" "unprognostic (8.04e-2)" "unprognostic (3.51e-2)" "unprognostic (4.48e-3)" "unprognostic (2.72e-3)" "unprognostic (3.37e-1)" "unprognostic (3.84e-2)" "prognostic unfavorable (5.28e-6)" "prognostic unfavorable (4.49e-4)" "unprognostic (3.56e-3)" "unprognostic (4.53e-3)" "unprognostic (2.87e-3)" "unprognostic (6.67e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.77e-2)" "unprognostic (4.70e-2)" "unprognostic (1.59e-1)" "unprognostic (1.16e-1)" 0.9 1.1 0.3 8.5 0.5 37.9 5.1 0.6 0.6 1.9 0.4 6.7 7.9 1.6 0.0 12.8 0.6 1.1 0.5 0.4 0.4 0.7 2.1 1.9 16.2 0.6 0.6 0.4 0.6 0.2 0.2 6.1 0.5 0.6 8.0 0.1 1.8 0.2 1.1 5.8 7.6 4.3 0.4 5.8 3.7 19.6 1.0 41.0 0.4 0.1 16.3 2.6 3.2 0.8 139.1 126.2 111.3 121.5 6.7 11.3 41.0 103.6 57.5 144.0 94.2 104.0 52.9 140.7 41.5 60.5 108.7 71.9 113.6 66.6 125.2 48.2 157.5 93.2 71.4 123.1 0.8 90.8 67.0 3.9 4.5 79.8 59.2 21.0 103.5 104.3 118.8 116.0 112.6 79.7 195.5 86.2 83.4 96.3 218.0 100.5 180.2 108.4 34.5 50.2 136.8 94.8 80.3 88.6 71.7 54.1 117.5 84.8 39.5 173.1 152.6 76.0 150.4 83.3 72.2 163.3 63.3 37.8 154.4 0.0 0.0 0.0 0.7 0.0 0.1 2.4 4.1 2.8 0.8 0.2 0.0 0.4 0.5 2.4 0.0 0.2 14.1 3.1 0.3 0.5 0.6 0.6 0.4 0.4 0.6 0.6 0.5 0.4 1.0 0.8 1.2 0.0 20.0 0.0 15.9 8.2 3.7 12.2 2.8 0.7 7.7 8.6 2.3 2.8 10.8 0.0 0.0 74.7 3.3 10.7 0.0 2.0 94.1 5.4 5.1 8.8 3.0 166.7 0.4 0.0 162.0 15.1 8.6 6.9 9.5 42.7 12.8 2.7 52.1 0.0 0.2 17.1 10.2 13.7 13.8 68.4 3.1 9.6 1.8 0.0 0.6 0.4 7.2 0.0 0.3 0.4 2.5 0.7 50.2 2.8 3.2 0.1 2.6 0.5 6.6 0.9 15.2 191.1 58.2 31.3 6.5 19.2 10.1 3.4 38.8 6.3 BRCA1 "BRCC1, FANCS, PPP1R53, RNF53" ENSG00000012048 "BRCA1 DNA repair associated" P38398 17 43044295-43170245 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 42.5;Granulosa cells: 38.2;Spermatocytes: 105.8;Spermatogonia: 73.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 6.8;classical monocyte: 14.7;intermediate monocyte: 4.7;myeloid DC: 10.9;neutrophil: 11.3" "Group enriched" "Detected in all" 6 "dendritic cells: 10.9;granulocytes: 11.3;monocytes: 14.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB001946, HPA004840, HPA034966, HPA057371" Approved Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nuclear bodies" "CAB001946: , HPA004840: , HPA034966: AB_10795287, HPA057371: AB_2732611" "unprognostic (7.87e-3)" "unprognostic (6.97e-2)" "unprognostic (3.53e-3)" "unprognostic (2.39e-1)" "unprognostic (5.42e-2)" "unprognostic (7.07e-3)" "unprognostic (1.56e-3)" "unprognostic (4.14e-3)" "unprognostic (9.62e-3)" "unprognostic (2.47e-1)" "unprognostic (5.53e-3)" "unprognostic (1.28e-1)" "unprognostic (1.08e-4)" "unprognostic (1.08e-3)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (8.31e-2)" 3.1 1.8 4.2 7.5 7.2 13.0 3.6 4.7 5.2 2.7 2.7 6.8 3.2 3.1 2.2 4.0 3.7 1.9 3.0 3.6 4.1 2.0 5.6 3.2 10.3 5.6 5.0 2.8 2.8 5.9 2.8 3.8 6.0 2.4 7.4 8.2 3.2 1.6 4.2 6.0 5.1 3.9 3.7 3.9 3.6 13.0 5.5 14.5 7.8 3.7 11.2 2.8 2.4 10.8 44.1 69.1 37.8 30.1 6.0 13.4 36.6 50.6 21.5 41.9 39.3 42.3 33.4 100.8 9.1 19.0 49.0 49.5 51.9 28.3 69.5 46.9 38.0 48.1 54.0 37.1 1.3 86.0 39.9 3.8 4.5 63.1 20.0 10.6 22.3 46.6 73.7 42.2 39.7 30.0 72.0 27.8 20.5 29.1 18.7 49.0 79.8 40.8 15.4 42.1 25.8 27.4 38.8 12.5 19.4 25.5 33.9 39.6 13.8 37.2 29.6 49.0 53.2 20.1 51.2 75.5 29.6 49.6 39.4 6.8 14.7 2.2 1.5 4.7 1.5 1.2 1.5 1.2 10.9 2.1 1.3 1.5 11.3 1.5 2.0 1.7 0.5 17.5 4.2 7.2 4.7 5.2 3.6 4.1 5.6 5.0 6.0 3.7 5.5 10.8 5.0 0.0 2.8 9.4 5.8 2.9 4.5 1.9 1.2 10.3 4.4 5.2 10.1 5.7 3.5 1.8 22.9 12.8 8.1 6.2 0.0 3.0 11.9 14.0 6.3 4.7 0.0 42.5 3.0 1.1 18.2 7.4 6.1 4.2 8.2 38.2 5.3 18.3 10.1 11.8 4.4 7.5 0.0 3.9 2.8 8.0 2.5 6.4 0.0 4.7 4.9 2.4 5.2 3.0 18.7 1.7 2.4 1.5 16.6 2.3 1.1 1.0 10.0 22.8 6.6 13.7 5.5 105.8 73.5 8.2 2.3 4.0 4.7 9.7 12.7 3.4 BRI3BP "BNAS1, HCCR-2, HCCRBP-3, KG19" ENSG00000184992 "BRI3 binding protein" Q8WY22 12 124993645-125031231 "Predicted membrane proteins, Transporters" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 20.8" "Cell type enhanced" "Detected in many" "Late spermatids: 174.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 13.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Daudi: 114.9;U-698: 161.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014957 Approved Approved Nucleoplasm,Mitochondria NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 45: Intestine - Brush border" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria" "HPA014957: AB_1845447" "unprognostic (1.62e-2)" "unprognostic (6.82e-2)" "unprognostic (1.53e-2)" "unprognostic (9.95e-2)" "unprognostic (4.66e-2)" "unprognostic (1.20e-2)" "prognostic unfavorable (6.87e-4)" "unprognostic (7.65e-3)" "unprognostic (2.84e-2)" "unprognostic (3.47e-3)" "unprognostic (7.40e-2)" "unprognostic (4.82e-2)" "unprognostic (2.72e-3)" "unprognostic (1.44e-3)" "unprognostic (2.20e-1)" "unprognostic (9.20e-2)" "unprognostic (1.55e-1)" 3.3 2.0 9.2 8.9 10.7 5.5 5.5 8.2 10.7 3.0 7.1 15.5 20.8 2.1 2.2 6.8 4.1 4.8 2.5 9.2 7.9 6.9 4.8 2.8 13.8 9.6 9.7 1.5 5.1 9.1 2.1 2.1 10.2 2.9 15.3 10.0 2.5 2.2 1.7 5.5 18.8 2.6 9.1 5.9 8.2 1.8 9.1 7.0 4.4 2.1 16.2 2.5 2.6 9.4 34.1 43.8 13.8 12.5 10.9 5.6 24.1 22.2 4.6 13.7 7.1 36.1 22.3 114.9 27.8 5.0 8.9 38.7 30.7 17.3 10.9 26.9 25.5 58.4 16.9 24.8 2.2 86.8 72.2 2.5 9.9 15.0 7.1 5.3 5.1 41.0 23.5 8.0 12.0 31.3 45.1 33.3 9.9 29.9 17.3 30.2 23.0 30.7 17.3 46.8 19.0 13.2 27.6 26.9 9.2 4.6 48.8 60.8 5.9 13.0 16.2 12.5 23.4 26.9 49.7 161.8 11.9 28.7 29.1 4.2 2.2 13.1 0.8 1.6 0.8 1.4 0.6 0.7 1.7 1.5 0.5 0.7 2.2 0.9 1.2 4.2 0.7 0.6 9.2 10.7 8.2 10.7 9.2 7.9 9.6 9.7 10.2 9.1 9.1 9.4 3.4 9.6 10.4 13.4 23.6 12.2 9.1 8.2 5.2 37.1 14.9 6.3 7.2 31.5 9.2 9.2 14.6 15.4 24.3 65.5 3.9 9.1 25.6 16.1 7.2 5.1 7.8 21.5 32.6 10.4 24.0 7.1 32.1 18.0 18.4 7.2 4.2 27.4 19.8 25.2 43.8 42.8 8.2 31.5 26.1 174.4 1.2 23.6 10.6 11.2 28.8 12.1 9.2 11.1 23.4 17.1 43.3 4.1 39.5 9.6 60.2 12.7 15.0 27.9 0.0 9.2 6.9 1.1 11.5 20.7 18.3 5.2 11.5 6.8 72.6 9.7 BRIP1 "BACH1, FANCJ, OF" ENSG00000136492 "BRCA1 interacting protein C-terminal helicase 1" Q9BX63 17 61679139-61863528 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Helicase, Hydrolase" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 7.2;lymphoid tissue: 5.9;testis: 7.0" "Group enriched" "Detected in many" 12 "Early spermatids: 186.2;Late spermatids: 194.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 88.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005474 Approved Supported "Nucleoplasm,Nuclear membrane" NA Yes "Cluster 26: Non-specific - Mitochondria" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Nuclear membrane" "HPA005474: AB_2667333" "unprognostic (1.88e-1)" "unprognostic (1.55e-2)" "prognostic favorable (3.45e-5)" "unprognostic (6.85e-4)" "unprognostic (3.09e-1)" "prognostic favorable (3.62e-4)" "unprognostic (2.60e-3)" "unprognostic (5.60e-2)" "unprognostic (5.66e-3)" "unprognostic (6.71e-2)" "unprognostic (1.50e-3)" "unprognostic (2.75e-2)" "unprognostic (3.41e-12)" "unprognostic (1.19e-2)" "unprognostic (2.25e-1)" "unprognostic (3.96e-2)" "unprognostic (3.62e-3)" 0.3 0.3 0.8 1.7 0.6 7.2 0.9 1.3 0.9 0.4 0.0 1.7 2.0 0.8 0.4 1.5 0.3 0.6 0.1 0.5 0.2 0.3 1.6 0.4 2.8 0.3 0.0 1.1 0.3 0.1 0.0 0.8 0.4 0.4 1.9 0.5 0.4 0.2 0.1 2.0 1.9 0.9 0.0 0.7 0.9 7.0 0.2 5.9 0.3 0.1 3.3 0.7 0.6 0.8 26.6 9.4 25.0 14.1 0.9 2.1 5.5 23.6 13.3 24.6 31.8 9.5 8.0 14.9 5.2 4.9 7.7 9.2 12.8 4.5 33.3 3.8 15.8 15.5 14.4 10.5 0.2 20.3 8.8 0.6 0.4 20.2 5.1 3.4 5.0 14.8 11.6 10.5 14.4 88.9 32.5 6.7 5.3 5.9 7.3 19.7 50.1 7.1 3.0 12.8 10.0 24.2 9.4 3.0 3.3 9.1 8.3 7.3 4.5 36.9 26.5 13.5 26.6 6.3 13.3 16.6 7.3 9.3 8.8 1.0 0.1 0.4 0.1 0.0 0.1 0.5 0.3 0.1 0.1 0.6 0.4 0.2 0.3 0.1 0.1 0.1 1.0 0.1 0.8 0.6 1.3 0.9 0.5 0.2 0.3 0.0 0.4 0.0 0.2 0.8 0.2 0.0 0.5 1.0 1.6 2.3 1.3 0.8 0.6 0.3 1.1 1.8 0.6 0.0 4.0 0.0 0.0 2.0 2.0 1.8 0.0 0.3 186.2 0.7 1.7 0.8 0.0 7.4 4.6 0.2 3.0 2.0 2.0 1.6 0.0 15.5 0.4 3.4 1.7 0.0 3.3 1.8 0.0 0.8 1.1 194.1 1.2 1.0 3.6 2.8 0.6 0.2 1.0 1.5 1.0 0.8 0.1 1.2 4.8 0.4 1.4 0.2 0.8 0.2 0.0 2.5 1.8 12.1 6.0 2.9 0.4 0.3 2.3 2.1 4.7 0.7 BTF3 "BTF3a, BTF3b, NACB" ENSG00000145741 "Basic transcription factor 3" P20290 5 73498408-73505635 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013007, HPA056420" Approved Supported Cytosol NA Yes 180000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Cytosol "CAB013007: , HPA056420: AB_2683125" "unprognostic (3.48e-3)" "unprognostic (2.11e-1)" "unprognostic (2.87e-3)" "unprognostic (1.86e-1)" "unprognostic (6.25e-2)" "unprognostic (1.41e-1)" "unprognostic (1.90e-3)" "unprognostic (1.78e-2)" "unprognostic (8.20e-3)" "unprognostic (5.18e-2)" "unprognostic (8.47e-2)" "unprognostic (1.01e-1)" "unprognostic (2.36e-2)" "unprognostic (1.06e-1)" "unprognostic (2.87e-1)" "unprognostic (1.26e-2)" "unprognostic (2.16e-1)" 633.3 440.1 241.0 373.7 251.2 861.1 763.0 250.7 307.9 658.2 234.9 593.6 460.9 547.0 422.0 735.8 584.3 376.6 477.8 230.9 261.7 469.8 522.5 416.4 644.4 256.5 247.8 1180.8 609.6 401.9 288.1 429.5 259.1 441.1 540.1 183.9 509.2 390.8 880.0 782.4 446.7 459.1 256.5 393.7 534.8 181.7 242.0 629.3 440.1 600.1 758.9 624.2 626.6 272.0 1148.3 747.2 798.7 1145.9 779.6 1301.4 1246.4 781.1 1084.9 1327.8 1267.4 972.1 1267.3 1719.2 1203.2 816.0 963.9 787.9 1176.6 2011.7 1517.2 716.2 1502.5 976.3 652.7 1280.2 1132.7 934.0 754.5 1139.7 1597.0 857.6 1572.3 1512.0 1227.4 975.3 924.1 1087.8 1134.7 1037.8 1410.0 1735.0 1017.4 423.0 742.0 1061.5 944.4 2147.0 1414.6 1126.0 930.6 1239.4 767.0 861.7 1650.4 744.4 1108.4 1884.6 894.7 569.6 780.5 690.2 2142.1 1020.7 1114.3 1607.2 757.0 1405.3 862.8 261.1 883.1 221.9 535.6 684.0 907.0 957.3 906.7 754.3 1140.2 788.4 986.3 892.7 116.0 878.6 556.1 637.6 1146.0 2128.9 241.0 251.2 250.7 307.9 230.9 261.7 256.5 247.8 259.1 256.5 242.0 272.0 753.2 246.8 324.7 17.0 889.7 1962.5 2039.6 2425.9 1664.7 138.9 1675.6 2355.4 357.8 566.2 908.0 323.7 43.8 1370.6 740.7 648.3 909.8 971.1 718.0 502.1 809.7 864.3 592.8 968.4 25.2 1219.7 2062.4 753.8 465.3 646.9 417.7 935.1 742.8 439.4 1066.3 85.8 29.3 1169.4 787.3 968.7 1357.2 464.2 1248.3 803.3 791.5 29.0 1487.9 376.5 726.1 20.6 49.6 1221.7 998.2 846.3 540.1 1626.5 1308.9 1229.5 432.9 137.6 644.2 1023.8 1051.0 333.7 238.2 1582.0 1953.2 1712.1 868.7 1029.7 1337.1 2269.9 CALM2 "CAMII, PHKD" ENSG00000143933 "Calmodulin 2" P0DP24 2 47160083-47176921 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007790, HPA044999" Approved NA Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB007790: AB_562257, HPA044999: AB_2679177" "prognostic unfavorable (5.05e-4)" "unprognostic (2.94e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.84e-4)" "unprognostic (9.21e-2)" "unprognostic (2.04e-3)" "prognostic unfavorable (8.35e-5)" "unprognostic (1.63e-2)" "unprognostic (4.67e-3)" "unprognostic (1.79e-2)" "unprognostic (1.97e-2)" "unprognostic (1.24e-2)" "unprognostic (1.14e-1)" "unprognostic (1.18e-2)" "unprognostic (2.29e-2)" "prognostic favorable (1.94e-5)" "unprognostic (1.24e-1)" 509.3 652.1 1177.9 334.4 1219.1 240.3 686.1 1229.7 1745.6 420.1 988.8 683.9 549.8 507.6 551.1 366.8 526.5 390.8 443.0 1229.0 1219.0 445.7 493.1 505.6 427.9 1209.1 1192.8 416.1 213.3 332.3 441.3 468.9 1227.6 449.1 706.0 574.8 490.8 561.5 262.9 304.2 621.2 634.7 1209.4 643.0 390.4 508.8 1257.9 571.0 443.3 258.1 467.2 459.0 340.2 1411.8 2459.6 905.8 1062.2 459.7 579.4 679.5 655.8 2177.2 1504.3 1437.1 1240.1 958.1 923.2 956.1 979.5 1753.2 1030.4 624.7 878.3 855.6 1907.0 729.3 438.6 821.6 526.6 1409.6 779.5 996.3 686.2 381.2 825.0 1265.3 1347.0 1230.4 977.3 312.8 812.1 854.7 3485.7 635.9 1270.2 984.3 801.3 2961.6 488.6 314.3 1142.9 1021.9 1631.0 441.0 756.8 2016.6 726.5 756.0 1120.1 1144.3 573.7 556.7 1084.8 1060.8 1135.8 627.0 1703.6 648.8 529.1 1038.2 718.8 711.3 1357.7 944.7 447.6 776.8 139.7 844.1 177.2 285.6 203.4 213.2 354.0 182.1 173.7 201.6 417.9 277.1 761.4 445.6 227.4 496.5 1177.9 1219.1 1229.7 1745.6 1229.0 1219.0 1209.1 1192.8 1227.6 1209.4 1257.9 1411.8 597.4 1387.8 613.5 195.2 570.7 1780.5 1101.0 2616.3 524.8 654.3 844.4 572.9 639.6 581.9 1751.8 759.6 98.0 931.4 649.8 906.5 2304.8 1977.0 312.7 889.1 363.8 652.0 597.1 697.1 317.5 683.4 627.9 943.6 354.8 452.5 665.4 484.5 280.6 536.6 1267.1 341.6 179.0 1020.1 3352.8 867.1 1858.2 287.0 1055.3 911.0 1771.6 143.4 1167.2 2063.1 350.1 129.7 339.8 2584.9 1114.4 863.6 309.7 1016.8 1231.6 1020.2 3245.3 334.2 907.2 671.6 1882.0 2193.5 714.3 503.0 1663.1 255.3 669.1 615.4 771.1 1062.2 CANT1 "SCAN-1, SHAPY" ENSG00000171302 "Calcium activated nucleotidase 1" Q8WVQ1 17 78991716-79009867 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 139.5;Intestinal goblet cells: 155.6;Syncytiotrophoblasts: 101.5;Undifferentiated cells: 100.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 445.4;T-47d: 282.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019627, HPA019639, HPA022818" Enhanced Supported "Golgi apparatus" NA Yes 3300000 "Cluster 52: Eosinophils - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus" "HPA019627: AB_1845969, HPA019639: AB_1845970, HPA022818: AB_1845971" "unprognostic (1.98e-2)" "unprognostic (2.49e-2)" "unprognostic (1.50e-2)" "unprognostic (5.36e-2)" "unprognostic (2.13e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (1.41e-4)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.76e-1)" "unprognostic (9.00e-2)" "unprognostic (3.30e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (6.21e-4)" "unprognostic (7.04e-2)" "unprognostic (5.06e-2)" "unprognostic (1.16e-1)" "unprognostic (7.23e-2)" 15.8 23.9 10.4 24.7 12.4 19.1 25.4 13.6 11.3 32.3 13.8 89.2 51.9 17.4 8.7 44.8 18.2 25.2 17.0 11.1 12.6 16.1 17.3 16.4 15.2 14.6 14.5 14.6 19.6 24.5 17.5 25.9 13.9 71.8 82.8 7.4 62.7 32.4 14.9 14.9 55.5 15.5 13.8 26.5 51.1 20.7 14.5 14.7 13.9 12.4 15.1 16.7 21.7 17.8 106.5 112.1 31.9 46.3 29.7 35.2 38.9 66.0 51.3 66.7 55.9 53.8 99.6 25.3 36.1 46.1 83.0 53.7 27.1 49.8 68.4 43.0 46.4 33.7 34.1 45.9 25.0 33.0 51.6 33.7 32.4 62.7 34.2 40.9 116.1 42.5 42.3 43.2 46.4 58.4 50.2 19.8 22.1 445.4 103.1 27.6 51.8 29.8 29.8 53.5 45.6 45.4 33.9 227.2 50.2 50.3 282.6 38.6 56.6 101.9 90.5 46.4 83.1 48.9 43.8 24.3 64.4 24.9 65.3 6.3 4.0 8.7 5.5 4.4 5.7 3.9 4.3 4.8 3.8 2.5 4.1 4.1 17.4 3.1 3.0 2.7 3.6 4.6 10.4 12.4 13.6 11.3 11.1 12.6 14.6 14.5 13.9 13.8 14.5 17.8 12.6 28.9 20.6 5.9 11.8 16.6 15.3 16.8 6.8 6.4 49.9 16.3 13.3 14.3 15.1 12.9 14.6 36.6 8.9 139.5 3.9 34.7 14.0 10.7 13.1 16.3 51.0 15.2 4.1 28.8 39.4 13.5 38.2 19.0 5.7 20.0 41.7 14.4 24.9 5.0 5.2 155.6 16.2 12.4 9.5 15.7 11.8 14.2 14.2 3.7 18.1 8.1 11.3 5.0 10.2 37.7 55.8 7.5 16.6 33.4 39.4 6.7 9.7 8.7 6.6 9.5 13.3 23.9 5.8 12.0 13.1 101.5 11.1 11.3 100.2 19.4 CASP2 "ICH1, MGC2181, NEDD2, PPP1R57" ENSG00000106144 "Caspase 2" P42575 7 143288215-143307696 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 51.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012175, HPA050678" Approved Approved Nucleoplasm NA Yes "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "CAB012175: , HPA050678: AB_2681214" "unprognostic (6.96e-2)" "prognostic favorable (7.38e-4)" "unprognostic (2.74e-2)" "unprognostic (7.51e-2)" "unprognostic (4.24e-2)" "unprognostic (2.39e-2)" "prognostic unfavorable (2.34e-4)" "unprognostic (1.74e-2)" "unprognostic (1.34e-2)" "prognostic favorable (2.89e-4)" "unprognostic (1.91e-2)" "unprognostic (1.64e-1)" "prognostic unfavorable (5.01e-6)" "unprognostic (2.66e-3)" "unprognostic (9.48e-2)" "unprognostic (1.19e-1)" "unprognostic (1.64e-1)" 10.3 6.6 6.0 13.9 6.7 40.2 10.5 7.8 6.7 11.8 6.7 11.1 10.7 10.2 9.6 15.3 10.3 7.0 8.4 5.9 6.2 9.1 6.4 10.4 22.0 7.2 6.4 9.3 8.4 11.1 5.3 12.4 7.7 7.6 12.7 7.7 11.9 6.3 3.9 17.4 15.4 9.4 5.9 19.0 9.6 9.1 6.9 27.5 8.8 5.0 27.1 7.5 11.2 10.0 27.5 25.4 28.8 51.0 15.1 17.5 15.4 27.7 13.0 25.4 27.8 26.0 31.3 52.0 25.9 18.4 19.4 27.3 29.4 22.6 34.0 45.8 22.5 31.2 40.4 18.3 8.4 60.7 37.4 13.0 18.1 31.0 11.0 11.3 22.0 41.3 26.3 32.6 27.5 27.5 109.1 64.4 36.5 27.4 26.3 79.1 14.6 32.6 15.1 23.3 31.5 34.2 54.8 24.3 17.3 19.6 26.3 23.4 24.1 22.5 15.5 40.7 28.1 27.0 28.5 59.4 24.9 72.6 41.1 69.2 17.9 17.2 24.5 21.7 24.2 25.7 33.3 25.3 17.3 28.8 24.3 28.3 21.7 24.2 34.1 21.1 38.9 15.3 6.0 6.7 7.8 6.7 5.9 6.2 7.2 6.4 7.7 5.9 6.9 10.0 14.1 9.6 8.3 4.2 17.4 15.2 7.0 9.4 6.2 4.8 19.0 13.5 6.2 17.2 7.0 7.3 8.4 20.0 19.3 8.7 3.9 8.1 36.6 10.8 17.9 16.4 10.7 9.7 11.2 7.7 14.6 9.3 8.2 20.1 10.1 22.7 18.2 7.2 10.1 6.7 8.8 11.5 0.0 16.9 23.3 51.0 11.8 12.2 21.4 4.7 20.8 4.4 13.4 4.5 22.4 9.4 5.9 8.2 13.0 5.8 9.1 4.2 4.9 15.4 0.0 8.3 10.9 13.7 25.9 16.1 13.8 5.7 16.7 9.3 15.5 7.0 CBX3 HP1Hs-gamma ENSG00000122565 "Chromobox 3" Q13185 7 26201162-26213607 "Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001973, HPA004902" Supported Supported "Nucleoplasm,Nuclear bodies" NA Yes 180000 "Cluster 49: Eosinophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "CAB001973: , HPA004902: AB_1850635" "prognostic unfavorable (7.92e-4)" "unprognostic (1.43e-1)" "unprognostic (4.84e-2)" "unprognostic (1.12e-2)" "unprognostic (4.85e-2)" "unprognostic (9.25e-3)" "prognostic unfavorable (2.20e-8)" "unprognostic (2.13e-2)" "unprognostic (3.95e-2)" "unprognostic (3.71e-3)" "prognostic unfavorable (4.00e-4)" "unprognostic (1.16e-1)" "prognostic unfavorable (4.56e-7)" "unprognostic (7.79e-2)" "unprognostic (4.69e-2)" "unprognostic (1.17e-1)" "unprognostic (5.78e-2)" 76.2 93.0 55.5 99.2 57.8 168.8 98.5 58.8 74.1 65.0 56.6 75.3 105.8 76.7 79.7 63.9 62.9 58.5 64.2 54.2 63.2 87.6 84.9 62.1 145.7 60.2 61.0 79.5 56.3 51.5 40.5 88.8 60.7 56.6 87.2 122.7 61.3 59.8 87.2 54.7 99.0 65.9 60.2 82.0 61.7 99.6 58.2 190.4 55.3 68.6 140.4 84.1 55.7 63.6 365.4 156.3 330.0 332.2 115.0 205.8 257.8 275.9 209.1 205.2 207.2 185.8 296.8 544.1 218.7 183.9 440.6 283.0 275.7 231.2 332.1 151.8 209.1 312.8 201.0 208.5 126.1 508.3 294.7 153.9 197.5 163.2 231.2 253.9 281.7 343.2 506.1 263.9 351.7 207.5 489.4 625.9 424.4 311.3 225.1 313.6 303.9 452.3 303.8 201.4 401.1 448.2 230.5 482.6 274.9 345.3 412.4 455.1 212.0 186.0 340.5 222.1 376.8 394.6 596.5 929.3 163.2 422.3 864.3 135.7 85.9 137.7 77.3 116.3 96.9 86.8 114.4 96.1 89.1 77.7 118.4 119.6 92.6 99.2 123.2 72.4 148.3 87.2 55.5 57.8 58.8 74.1 54.2 63.2 60.2 61.0 60.7 60.2 58.2 63.6 139.1 109.0 98.4 16.3 158.5 143.6 93.3 128.0 105.3 101.8 223.8 181.0 124.1 133.0 119.7 64.4 77.2 176.3 138.7 111.2 140.8 167.6 162.2 132.4 215.4 142.6 110.2 306.6 27.4 141.4 362.1 123.6 81.1 129.0 222.0 166.2 145.3 289.2 143.1 50.5 26.8 156.6 107.8 254.9 200.0 41.9 136.4 157.6 104.9 15.0 183.3 155.9 166.9 23.1 35.8 166.3 103.8 98.2 129.1 135.1 112.6 187.4 107.3 132.1 78.9 60.0 110.1 274.5 388.6 112.5 107.8 270.8 155.2 133.1 205.9 110.9 CBX6 ENSG00000183741 "Chromobox 6" O95503 22 38861422-38872249 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 88.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048653 Uncertain Approved Nucleoplasm,Mitochondria NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Mitochondria" "HPA048653: AB_2680479" "unprognostic (1.65e-2)" "unprognostic (8.66e-2)" "unprognostic (6.20e-3)" "unprognostic (3.14e-3)" "unprognostic (1.56e-1)" "unprognostic (2.62e-1)" "prognostic unfavorable (8.30e-4)" "unprognostic (2.90e-2)" "unprognostic (3.72e-3)" "unprognostic (5.97e-2)" "prognostic favorable (2.46e-6)" "unprognostic (2.75e-1)" "unprognostic (1.27e-3)" "unprognostic (7.39e-2)" "unprognostic (1.03e-1)" "unprognostic (1.94e-1)" "unprognostic (2.26e-2)" 16.3 22.4 67.1 16.5 53.6 28.3 12.3 9.9 83.6 21.0 0.0 39.3 6.5 34.0 14.5 13.3 27.0 11.3 17.7 88.2 10.1 18.7 6.3 17.2 14.2 16.6 14.0 24.4 17.1 49.5 27.5 4.3 10.0 22.0 7.2 8.5 13.7 25.9 8.9 8.2 17.1 26.1 5.5 15.9 20.5 4.3 21.8 12.5 19.0 6.7 15.3 31.0 11.9 30.8 40.3 41.7 9.1 31.3 68.5 38.2 2.8 42.8 24.5 21.8 20.3 21.1 36.5 65.3 31.2 29.5 15.3 46.8 17.0 18.3 11.9 63.1 53.0 6.7 18.5 7.4 37.2 32.6 31.1 57.0 9.1 49.7 23.5 30.1 24.9 18.4 14.9 32.2 15.1 45.5 20.2 9.5 8.1 23.1 31.9 29.9 30.5 25.9 31.3 37.4 44.3 9.8 27.5 36.4 23.7 3.2 25.0 19.3 32.7 18.9 57.9 33.2 29.6 32.9 34.1 23.5 37.0 33.6 40.1 2.2 9.1 4.7 18.6 12.4 15.3 6.7 12.6 13.1 9.1 7.7 10.3 12.6 4.0 9.1 12.5 46.1 8.0 20.0 67.1 53.6 9.9 83.6 88.2 10.1 16.6 14.0 10.0 5.5 21.8 30.8 30.5 16.0 14.7 9.8 25.1 33.9 47.4 18.4 16.5 100.4 42.6 31.6 27.5 52.9 22.1 73.5 39.6 12.4 83.0 9.6 35.2 102.6 1.1 6.9 46.0 36.4 122.7 17.7 28.9 50.1 2.0 48.5 3.1 17.5 6.3 18.7 46.8 32.4 19.8 124.5 27.3 3.2 30.5 40.8 121.1 2.9 74.3 33.2 81.8 14.0 91.1 91.2 57.7 15.1 23.3 46.9 9.1 80.9 24.5 58.9 0.1 51.7 18.0 59.4 72.3 54.4 85.1 4.2 6.8 10.4 34.0 4.7 35.8 40.9 0.9 82.6 CCNB1 CCNB ENSG00000134057 "Cyclin B1" P14635 5 69167135-69178245 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 52.9;lymphoid tissue: 76.2" "Cell type enriched" "Detected in many" 6 "Extravillous trophoblasts: 723.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 3.0;white matter: 8.3" "Not detected" "Not detected" "CAB000115, CAB003804, HPA030741, HPA061448" Enhanced Enhanced Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "CAB000115: , CAB003804: AB_562272, HPA030741: AB_2673586, HPA061448: AB_2684522" "unprognostic (4.12e-2)" "unprognostic (2.75e-2)" "unprognostic (1.91e-3)" "unprognostic (4.08e-3)" "unprognostic (2.78e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.54e-7)" "prognostic unfavorable (3.38e-4)" "unprognostic (1.43e-2)" "unprognostic (1.63e-2)" "unprognostic (2.49e-3)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.11e-16)" "unprognostic (2.44e-1)" "unprognostic (3.73e-1)" "unprognostic (1.44e-1)" "unprognostic (5.15e-3)" 4.0 5.1 4.0 26.0 3.9 52.9 10.0 6.0 4.9 6.3 2.8 22.2 20.9 7.7 5.4 36.0 8.2 4.0 3.0 3.8 4.0 4.8 4.3 3.9 54.5 6.2 4.4 5.0 4.2 5.8 2.6 20.8 6.5 3.8 29.5 5.7 6.5 3.9 3.4 14.5 19.5 14.4 3.5 11.1 10.8 32.9 5.2 76.2 9.3 2.0 67.0 8.4 10.4 4.0 466.0 317.1 423.5 377.1 22.2 37.1 980.2 201.3 150.8 521.3 437.0 471.2 423.9 285.2 239.1 187.6 594.2 284.2 432.4 442.8 577.2 281.4 217.2 181.6 243.2 323.2 6.8 160.5 197.7 16.6 27.7 300.5 207.2 47.7 282.8 274.2 223.5 217.9 430.2 441.4 220.5 184.7 236.7 153.3 199.3 228.4 305.2 288.2 192.6 168.2 212.7 133.5 347.7 160.3 141.9 236.4 306.4 162.5 119.8 114.4 368.5 207.6 510.2 109.2 216.6 399.8 158.8 271.9 358.6 3.1 2.0 1.5 3.2 5.1 4.5 15.4 8.3 7.4 6.0 11.1 2.7 2.6 1.3 8.2 2.4 5.0 17.6 6.2 4.0 3.9 6.0 4.9 3.8 4.0 6.2 4.4 6.5 3.5 5.2 4.0 4.0 0.0 0.5 2.0 11.8 11.5 7.2 32.1 4.6 4.8 9.8 12.3 1.9 1.5 8.8 5.5 2.1 108.2 8.3 9.5 1.9 6.5 110.2 15.2 7.4 6.6 1.2 76.2 2.7 1.4 723.1 18.3 21.4 13.0 2.5 63.0 8.9 3.2 60.2 0.0 2.1 13.8 73.2 12.0 7.2 17.8 3.1 9.7 3.6 1.0 2.7 3.9 2.1 0.5 1.0 2.4 1.5 2.6 24.1 4.5 2.5 5.6 13.1 4.1 6.6 4.9 18.5 74.3 62.2 37.4 7.2 41.5 8.0 11.8 33.4 7.8 CCNB2 HsT17299 ENSG00000157456 "Cyclin B2" O95067 15 59105126-59125045 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 74.6;lymphoid tissue: 73.1;testis: 69.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 67.9;Early spermatids: 228.5;Erythroid cells: 123.6;Extravillous trophoblasts: 128.3;Spermatocytes: 288.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 5 "T-reg: 22.7" "Lineage enriched" "Detected in many" 6 "T-cells: 22.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA008873, CAB009575" Enhanced Enhanced "Golgi apparatus,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Golgi apparatus" "CAB009575: AB_2072392, HPA008873: AB_1078604" "unprognostic (2.69e-2)" "unprognostic (2.25e-1)" "unprognostic (4.43e-2)" "unprognostic (1.96e-2)" "unprognostic (1.77e-1)" "unprognostic (4.65e-2)" "prognostic unfavorable (2.83e-4)" "prognostic unfavorable (4.63e-4)" "prognostic unfavorable (3.21e-5)" "unprognostic (1.09e-1)" "prognostic unfavorable (1.74e-5)" "unprognostic (4.48e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.96e-1)" "unprognostic (1.41e-1)" "unprognostic (3.98e-2)" "unprognostic (4.44e-1)" 1.0 1.1 0.4 12.2 1.1 74.6 2.9 0.7 0.7 2.9 1.1 14.3 14.1 2.6 0.3 16.1 1.1 1.9 0.7 0.6 0.7 1.1 1.4 2.2 33.0 1.3 1.0 0.8 0.7 0.2 0.3 11.4 1.0 1.6 16.8 0.3 2.8 0.4 0.7 9.4 12.0 6.4 0.7 7.1 5.6 69.4 1.1 73.1 1.0 0.4 43.7 3.6 5.6 2.2 132.5 112.1 188.6 47.1 8.5 16.6 97.5 104.8 69.9 165.2 135.6 187.8 81.1 122.1 75.4 71.8 97.2 160.1 181.4 92.6 157.8 124.1 92.4 153.1 127.3 108.1 2.5 118.1 98.6 6.3 12.6 71.4 91.9 32.7 114.1 147.0 163.1 194.5 128.2 96.5 137.9 177.2 138.6 58.5 65.2 157.5 260.0 124.4 53.3 91.9 115.2 75.9 148.9 80.2 97.3 147.9 139.4 120.4 58.5 81.6 134.4 90.5 210.5 84.2 133.2 213.8 53.6 267.1 117.9 0.0 0.1 0.7 0.1 0.0 0.3 2.1 4.6 5.0 3.0 1.7 0.0 0.1 0.8 3.6 0.1 0.1 22.7 2.1 0.4 1.1 0.7 0.7 0.6 0.7 1.3 1.0 1.0 0.7 1.1 2.2 0.3 0.0 0.6 0.0 6.8 4.8 2.8 11.5 1.8 0.2 2.5 3.3 0.5 0.0 3.2 0.0 0.0 67.9 1.6 4.1 0.0 0.7 228.5 5.3 3.1 3.9 3.0 123.6 0.7 0.2 128.3 7.2 7.1 5.9 0.0 29.9 6.1 1.1 29.9 0.0 0.8 10.1 20.3 10.6 3.3 53.5 4.4 7.9 0.0 0.0 2.4 0.2 1.0 0.0 1.4 0.4 1.9 1.9 18.7 2.3 2.1 0.0 1.8 0.3 0.0 1.0 5.7 288.7 32.1 20.3 6.1 16.3 4.4 4.1 23.4 5.0 CCND2 ENSG00000118971 "Cyclin D2" P30279 12 4269771-4305353 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 354.3;Granulosa cells: 438.5;Langerhans cells: 255.3;Plasma cells: 371.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 152.4;HBEC3-KT: 136.6;HDLM-2: 238.8;Karpas-707: 287.9;RH-30: 202.7;RPMI-8226: 114.2" "HPA049138, HPA054196" Approved Enhanced Nucleoplasm Yes Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA049138: AB_2680650, HPA054196: AB_2682412" "unprognostic (2.98e-3)" "unprognostic (1.15e-1)" "unprognostic (7.21e-2)" "unprognostic (1.65e-2)" "unprognostic (1.70e-2)" "unprognostic (4.82e-2)" "unprognostic (4.94e-2)" "unprognostic (2.01e-3)" "unprognostic (3.16e-2)" "unprognostic (1.66e-2)" "prognostic favorable (2.52e-4)" "unprognostic (1.75e-1)" "unprognostic (1.25e-1)" "unprognostic (8.23e-2)" "unprognostic (4.52e-1)" "prognostic favorable (9.76e-5)" "unprognostic (7.06e-2)" 20.0 52.6 5.4 8.7 12.9 20.3 13.0 0.0 13.5 26.9 0.0 40.8 17.4 26.1 7.5 12.2 22.1 2.7 51.9 14.4 1.1 9.7 1.9 17.2 5.3 9.6 0.2 14.2 24.5 9.9 23.5 12.9 2.7 20.7 10.4 0.7 10.8 9.1 1.8 12.6 25.9 9.8 7.8 19.7 12.7 4.0 0.0 3.2 20.3 0.0 5.1 26.5 19.9 4.5 0.0 0.0 152.4 0.0 10.1 0.4 0.0 0.0 0.0 0.0 0.0 62.8 0.0 0.0 0.4 0.0 0.0 16.2 0.1 136.6 0.0 238.8 2.5 0.7 0.0 0.0 0.0 57.0 12.6 23.8 2.4 0.0 97.0 0.0 0.0 0.8 17.0 287.9 6.8 0.0 0.0 52.8 50.8 0.0 0.0 0.0 202.7 114.2 0.0 8.1 0.0 0.0 0.0 0.0 0.0 89.6 0.0 0.0 4.2 0.0 39.3 0.0 0.0 1.4 60.7 0.0 0.0 32.3 0.0 6.6 0.4 4.7 11.1 0.0 17.1 3.1 16.3 13.8 0.4 1.7 10.4 12.1 1.1 9.4 0.0 1.1 13.6 6.8 5.4 12.9 0.0 13.5 14.4 1.1 9.6 0.2 2.7 7.8 0.0 4.5 23.9 60.9 46.6 10.1 82.9 106.8 23.9 73.4 174.2 7.6 3.4 41.8 354.3 2.8 37.4 12.9 0.0 4.0 128.7 37.5 0.0 3.1 0.8 3.3 110.8 35.7 64.8 37.2 54.1 68.3 2.7 123.6 4.6 3.6 55.8 438.5 19.6 2.2 13.0 3.3 55.2 147.7 12.2 11.9 255.3 3.3 52.5 39.3 39.2 19.7 9.8 170.0 89.6 55.3 4.0 20.7 49.4 124.1 371.2 35.8 34.4 1.4 10.3 6.5 26.3 21.4 112.6 0.8 5.1 50.9 39.6 6.3 122.6 41.5 159.7 8.4 CCNE2 CYCE2 ENSG00000175305 "Cyclin E2" O96020 8 94879770-94896678 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 33.6;Oligodendrocytes: 34.5;Spermatocytes: 77.7;Spermatogonia: 26.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 5.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 101.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007825, CAB019374" Enhanced NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "CAB007825: AB_598148, CAB019374: " "unprognostic (1.80e-2)" "unprognostic (4.81e-2)" "unprognostic (7.49e-2)" "unprognostic (2.08e-2)" "unprognostic (2.36e-1)" "prognostic favorable (5.87e-4)" "unprognostic (8.37e-4)" "prognostic unfavorable (8.77e-4)" "unprognostic (3.18e-2)" "unprognostic (2.19e-2)" "unprognostic (3.64e-2)" "unprognostic (1.04e-2)" "unprognostic (7.01e-12)" "unprognostic (1.81e-2)" "unprognostic (1.50e-1)" "unprognostic (1.06e-2)" "unprognostic (3.03e-1)" 2.0 0.6 3.7 6.9 8.3 37.0 2.2 9.0 7.7 1.7 0.3 5.4 3.6 1.8 0.1 4.7 0.6 2.4 1.4 3.2 5.4 0.5 2.3 1.8 10.9 9.9 8.1 1.5 1.8 0.5 0.6 4.3 8.8 1.2 5.7 5.2 1.8 0.2 0.7 5.9 4.3 2.2 7.4 2.3 4.0 14.5 8.0 15.1 1.7 0.7 9.6 2.1 1.5 13.4 47.2 6.2 24.0 15.0 2.9 5.4 16.5 47.3 16.6 29.4 28.9 11.3 20.6 24.5 31.4 20.3 9.1 24.4 19.4 17.5 39.5 17.4 17.5 49.5 26.6 4.2 0.2 20.2 29.0 1.4 1.1 21.4 2.1 6.4 15.5 30.1 21.7 101.5 42.5 14.2 77.8 9.7 8.1 37.4 14.1 54.1 41.7 11.7 8.1 26.4 34.8 14.5 31.8 8.4 5.9 3.0 42.0 21.2 13.0 30.7 20.2 22.9 42.8 19.1 21.1 59.3 24.8 36.1 23.1 0.0 0.2 0.1 0.8 0.2 0.3 0.3 1.1 1.3 0.7 1.0 0.3 0.6 0.6 1.5 0.1 0.0 5.2 0.6 3.7 8.3 9.0 7.7 3.2 5.4 9.9 8.1 8.8 7.4 8.0 13.4 7.5 6.4 1.7 0.7 3.0 4.2 1.6 2.3 6.8 2.9 5.9 8.9 2.5 0.0 1.9 1.8 6.2 7.2 7.2 12.3 0.0 0.2 6.9 1.3 2.7 3.5 0.0 33.6 2.3 0.2 7.8 2.6 4.1 2.9 0.0 2.1 2.5 1.3 4.4 8.4 2.6 4.0 0.0 2.5 1.9 9.0 1.2 4.8 0.0 0.0 0.0 1.0 1.0 1.5 34.5 0.2 2.4 0.4 14.6 1.1 6.3 0.1 1.1 4.7 6.6 2.6 4.3 77.7 26.2 9.5 3.8 1.9 7.5 1.2 3.3 0.8 CDC20 "CDC20A, p55CDC" ENSG00000117399 "Cell division cycle 20" Q12834 1 43358981-43363203 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 53.9;lymphoid tissue: 52.6;testis: 49.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 65.0;Early spermatids: 135.0;Erythroid cells: 96.0;Extravillous trophoblasts: 146.2;Spermatocytes: 126.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7 "memory B-cell: 4.2;memory CD4 T-cell: 3.2;memory CD8 T-cell: 3.5;NK-cell: 9.5;T-reg: 11.6" "Group enriched" "Detected in many" 9 "B-cells: 4.2;NK-cells: 9.5;T-cells: 11.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB004525, HPA045842, HPA055288" Enhanced Enhanced Nucleoplasm,Cytosol Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "CAB004525: AB_628089, HPA045842: AB_2679470, HPA055288: AB_2682773" "unprognostic (1.66e-2)" "unprognostic (1.09e-1)" "unprognostic (1.73e-2)" "unprognostic (2.14e-3)" "unprognostic (1.58e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (4.00e-8)" "unprognostic (9.06e-3)" "unprognostic (1.17e-2)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.32e-4)" "unprognostic (8.55e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.84e-2)" "unprognostic (2.28e-1)" "unprognostic (2.01e-1)" "unprognostic (1.29e-2)" 1.6 1.5 0.6 16.2 1.1 53.9 5.2 0.8 1.3 3.5 0.4 14.8 13.7 2.3 2.5 27.2 1.7 1.2 0.9 0.7 1.1 2.3 1.7 2.5 32.6 1.3 1.1 0.7 0.6 0.2 0.3 9.7 1.1 0.8 16.0 0.2 4.4 0.7 0.3 11.3 12.2 7.3 0.8 11.7 7.0 49.1 1.7 52.6 1.7 0.2 50.8 3.3 7.0 1.3 311.9 148.2 202.8 133.4 6.9 17.6 193.5 140.3 125.0 400.0 211.4 234.5 250.9 178.3 80.1 130.1 140.6 212.8 225.3 267.9 331.5 140.8 165.6 261.4 143.6 147.3 2.1 184.3 91.4 6.0 12.4 278.2 249.6 35.1 172.2 167.5 120.2 119.3 184.0 120.4 179.2 113.5 257.2 147.0 196.9 255.8 277.9 112.9 98.5 81.3 119.2 58.9 248.1 165.8 76.6 154.9 116.3 231.7 90.2 118.9 276.2 133.7 445.0 90.6 86.7 185.7 85.2 227.6 181.6 0.0 0.1 0.0 0.3 0.0 0.0 4.2 3.2 3.5 0.9 0.9 0.1 0.3 0.7 9.5 0.0 0.2 11.6 2.8 0.6 1.1 0.8 1.3 0.7 1.1 1.3 1.1 1.1 0.8 1.7 1.3 2.1 0.0 1.1 0.0 12.2 10.5 3.8 17.6 6.2 0.5 6.4 9.7 0.7 1.5 4.8 0.0 0.0 65.0 2.8 16.9 0.0 2.2 135.0 14.6 2.4 4.5 0.0 96.0 0.2 0.4 146.2 9.3 11.7 4.6 0.0 46.5 7.9 1.3 37.4 0.0 0.0 18.5 24.4 6.2 7.5 18.5 2.8 9.3 0.0 0.0 1.8 0.3 0.0 0.0 1.6 0.7 0.5 1.9 34.4 2.7 3.2 3.1 8.3 2.9 0.0 1.0 25.4 126.5 39.8 47.3 8.4 10.7 5.1 1.6 37.5 7.4 CDC25A ENSG00000164045 "Cell division cycle 25A" P30304 3 48157146-48188417 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.3;lymphoid tissue: 8.8;testis: 13.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 111.2;Early spermatids: 18.3;Late spermatids: 31.8;Spermatogonia: 16.3" "Cancer enhanced" "Detected in many" "testis cancer: 19.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005855, HPA008803" Approved "Nucleoplasm,Golgi apparatus" NA Yes "Cluster 43: B-cells - Humoral immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "Golgi apparatus" "HPA005855: AB_1846364, HPA008803: " "unprognostic (1.49e-1)" "unprognostic (8.13e-2)" "unprognostic (1.20e-2)" "unprognostic (1.43e-3)" "unprognostic (2.14e-1)" "unprognostic (9.51e-2)" "unprognostic (7.05e-7)" "unprognostic (1.35e-2)" "unprognostic (4.32e-3)" "unprognostic (8.92e-3)" "unprognostic (4.41e-2)" "unprognostic (9.09e-2)" "unprognostic (4.41e-3)" "unprognostic (1.57e-3)" "unprognostic (1.07e-1)" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" 0.7 0.9 0.8 3.3 0.8 15.3 1.1 0.7 1.0 0.6 0.7 3.5 2.0 0.6 0.9 2.4 0.2 0.3 0.4 0.8 2.0 0.7 0.8 0.3 4.4 1.1 1.9 2.2 0.7 0.8 0.8 2.6 1.7 0.6 3.9 2.0 0.8 0.6 0.4 0.6 1.8 1.1 0.8 2.0 0.9 13.3 2.0 8.8 1.8 0.3 5.6 0.9 0.9 0.7 22.2 10.7 50.0 27.2 1.7 3.2 34.2 29.9 11.3 36.7 29.6 46.8 11.2 64.9 11.4 8.0 23.4 16.3 86.6 20.6 38.6 21.4 45.1 83.8 19.0 23.1 1.7 59.4 23.4 1.7 3.1 45.8 19.6 4.6 14.1 47.8 67.6 33.6 20.1 11.8 74.8 46.6 73.4 20.2 24.2 33.2 32.9 35.1 9.5 20.7 23.5 28.8 18.6 21.6 9.5 31.7 11.3 41.9 7.2 18.0 27.7 20.3 41.4 16.7 54.2 101.5 13.5 65.2 15.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.7 1.0 0.8 2.0 1.1 1.9 1.7 0.8 2.0 0.7 0.3 0.0 0.0 1.0 1.1 0.4 0.4 0.8 1.8 0.5 1.2 1.0 111.2 0.0 0.1 0.0 2.1 4.2 0.2 2.4 0.0 0.4 18.3 0.5 0.9 2.7 1.2 8.0 0.2 0.9 7.4 1.5 1.5 1.3 0.0 4.6 1.4 0.3 3.1 0.0 0.5 2.0 0.0 0.6 0.9 31.8 1.5 0.5 0.0 0.0 0.1 1.1 0.0 0.5 0.0 1.1 0.8 1.9 13.0 0.7 0.4 0.4 0.2 0.4 0.0 0.1 2.2 14.5 16.3 4.3 0.0 0.3 0.6 2.4 4.1 0.5 CDC25B ENSG00000101224 "Cell division cycle 25B" P30305 20 3786772-3806121 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "B-cells: 7.2;NK-cells: 18.1;T-cells: 28.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038892, HPA038893, HPA075215" Enhanced Uncertain "Vesicles,Mitotic spindle" Yes Yes "Cluster 20: T-cells - T-cell receptor" "Cluster 64: Macrophages - Immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Mitotic spindle" "HPA038892: AB_2676258, HPA038893: AB_2676259, HPA075215: " "unprognostic (4.69e-2)" "unprognostic (5.74e-2)" "unprognostic (2.93e-2)" "prognostic unfavorable (4.76e-4)" "unprognostic (1.13e-1)" "unprognostic (4.23e-1)" "prognostic unfavorable (1.19e-4)" "unprognostic (1.31e-2)" "unprognostic (4.92e-2)" "unprognostic (2.74e-1)" "unprognostic (1.67e-1)" "unprognostic (6.03e-2)" "prognostic unfavorable (2.94e-13)" "unprognostic (1.15e-1)" "unprognostic (2.38e-1)" "unprognostic (3.94e-1)" "unprognostic (9.46e-2)" 29.2 15.6 30.5 28.8 32.4 29.4 25.1 39.2 33.2 41.7 23.2 37.6 14.4 35.0 9.4 27.1 31.5 17.9 16.3 27.6 32.5 31.3 24.8 78.4 47.6 31.3 29.9 37.4 12.8 3.8 45.7 31.1 30.2 25.4 11.3 7.8 16.7 8.9 10.5 21.8 41.2 14.2 27.4 56.1 30.1 12.4 30.9 44.7 41.8 6.3 32.8 35.8 30.2 35.8 129.6 273.2 36.5 60.0 43.8 43.0 19.3 63.3 95.3 103.1 75.9 49.2 182.9 91.3 27.5 65.4 253.5 183.5 50.6 105.8 50.2 36.2 54.4 49.4 88.5 59.6 178.4 38.6 25.0 41.1 85.0 95.4 115.7 35.6 58.4 44.2 33.3 232.7 63.1 105.5 119.0 57.7 27.3 90.9 116.9 62.0 102.6 67.5 73.2 12.2 25.8 56.9 148.6 140.8 78.1 31.7 48.1 20.4 48.6 55.1 66.2 101.5 85.0 57.8 97.8 36.8 28.1 38.0 54.6 3.9 2.4 0.0 22.7 3.4 21.3 5.8 22.6 23.3 2.4 7.2 18.6 21.6 0.3 18.1 1.7 1.3 28.2 11.2 30.5 32.4 39.2 33.2 27.6 32.5 31.3 29.9 30.2 27.4 30.9 35.8 14.0 9.6 21.7 18.6 21.7 11.2 6.0 10.9 7.4 14.4 4.8 5.5 8.6 8.6 4.5 7.3 2.1 11.9 30.6 5.8 0.0 9.9 0.7 2.7 20.6 27.1 7.8 32.6 39.2 4.8 17.7 15.7 17.3 5.4 1.3 11.5 14.3 13.7 30.4 3.3 38.0 10.4 12.2 14.8 9.4 1.1 7.2 12.4 17.8 6.5 8.8 8.3 44.3 22.6 13.2 15.0 4.3 9.1 49.6 6.0 5.5 11.1 3.7 2.6 0.0 26.5 14.0 2.3 12.3 10.3 11.2 3.6 36.4 7.1 10.9 4.4 CDC45 "CDC45L, CDC45L2" ENSG00000093009 "Cell division cycle 45" O75419 22 19479457-19520612 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.4;lymphoid tissue: 20.4;testis: 23.4" "Cell type enhanced" "Detected in many" "Early spermatids: 120.5;Erythroid cells: 29.7;Spermatocytes: 72.3;Spermatogonia: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "K-562: 370.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000614, CAB009459" Enhanced Supported Nucleoplasm,Centrosome,Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Centrosome, Cytosol" "CAB009459: AB_2078507, HPA000614: AB_1078487" "unprognostic (5.56e-2)" "unprognostic (6.12e-3)" "unprognostic (1.17e-3)" "unprognostic (3.42e-3)" "unprognostic (3.57e-1)" "unprognostic (7.42e-2)" "prognostic unfavorable (6.95e-6)" "unprognostic (6.01e-3)" "unprognostic (1.85e-3)" "unprognostic (1.47e-2)" "prognostic unfavorable (8.94e-4)" "unprognostic (7.28e-2)" "unprognostic (0.00e+0)" "unprognostic (7.62e-3)" "unprognostic (2.02e-1)" "unprognostic (8.52e-2)" "unprognostic (1.10e-1)" 0.5 0.5 0.7 6.2 0.5 25.4 1.5 0.2 0.2 1.1 0.4 4.6 3.5 0.9 0.3 5.3 0.4 0.5 0.3 0.2 0.4 0.3 1.2 0.9 11.3 0.5 0.4 0.2 0.2 0.2 0.1 3.2 0.5 0.4 6.0 0.1 0.9 0.2 0.1 3.3 3.1 1.8 0.2 2.8 2.6 23.4 1.1 20.4 0.3 0.0 11.8 1.9 1.7 0.3 57.4 42.2 56.4 42.9 2.0 5.6 24.4 65.4 31.6 75.5 75.5 35.8 30.5 62.2 23.2 21.0 28.9 51.9 58.2 45.9 59.5 72.3 96.3 82.8 50.1 41.3 3.1 125.0 43.7 1.3 2.4 57.9 26.0 7.0 38.8 63.0 370.6 73.3 44.8 77.2 98.1 56.5 16.7 106.2 34.4 77.1 95.5 26.5 16.9 49.3 72.1 37.0 38.1 40.0 12.0 21.7 26.2 51.0 15.0 60.0 91.6 46.0 62.8 24.6 46.8 67.5 30.1 58.9 82.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.3 0.7 0.1 0.0 0.2 0.1 0.5 0.5 0.1 0.3 0.9 0.6 0.7 0.5 0.2 0.2 0.2 0.4 0.5 0.4 0.5 0.2 1.1 0.3 0.2 0.0 0.0 0.0 1.9 2.7 1.7 3.7 0.0 0.0 0.7 0.8 0.4 0.0 0.5 0.0 0.0 11.9 1.4 1.9 0.0 0.8 120.5 0.9 0.7 1.2 0.0 29.7 0.1 0.0 19.8 2.3 1.5 1.0 0.0 5.5 3.6 0.0 7.2 0.0 0.1 1.2 4.1 0.6 1.0 14.4 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.7 12.6 0.2 0.4 0.0 0.3 0.0 6.6 1.5 13.9 72.3 50.7 3.3 1.8 4.9 1.2 0.8 5.1 2.5 CDC6 CDC18L ENSG00000094804 "Cell division cycle 6" Q99741 17 40287879-40304657 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.2;lymphoid tissue: 17.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 23.2;Erythroid cells: 37.2;Extravillous trophoblasts: 34.6;Plasma cells: 31.6;Spermatocytes: 69.5;Spermatogonia: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.6" "Group enriched" "Detected in many" 6 "dendritic cells: 3.6;NK-cells: 1.5;T-cells: 2.4" "Cell line enhanced" "Detected in all" "SK-BR-3: 500.3" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA050114, HPA065070" Approved Approved "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "Cytokinetic bridge, Mitotic spindle" "HPA050114: AB_2681021, HPA065070: AB_2732729" "unprognostic (1.29e-1)" "unprognostic (7.22e-2)" "unprognostic (1.23e-3)" "unprognostic (7.97e-2)" "unprognostic (7.12e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (5.96e-8)" "unprognostic (2.31e-3)" "unprognostic (1.46e-3)" "unprognostic (1.41e-1)" "prognostic unfavorable (2.90e-4)" "unprognostic (5.47e-2)" "unprognostic (3.00e-15)" "unprognostic (1.86e-2)" "unprognostic (1.35e-1)" "unprognostic (3.95e-3)" "unprognostic (3.88e-2)" 2.1 1.9 0.5 13.7 0.8 27.2 3.4 0.2 1.9 3.2 0.0 8.4 7.5 2.2 1.1 5.7 1.0 2.8 0.6 1.1 0.1 0.5 3.0 1.4 16.4 0.1 0.0 0.9 1.9 0.8 0.5 9.3 0.3 1.1 8.7 0.5 1.3 1.2 0.3 2.8 6.7 3.7 0.0 3.7 3.6 10.1 0.2 16.7 1.7 0.5 17.1 4.3 1.8 0.6 155.1 119.0 115.1 86.5 6.7 12.7 118.0 159.9 49.0 149.2 166.5 135.8 64.9 123.9 99.6 35.9 85.9 214.0 112.2 76.2 148.9 64.5 98.4 96.2 122.3 134.6 4.4 133.3 55.1 4.7 8.1 156.4 107.1 14.8 46.9 84.2 183.0 109.0 71.9 95.8 199.3 43.3 101.6 96.9 48.7 145.0 286.8 119.9 30.3 184.8 85.6 76.9 146.9 500.3 55.4 100.3 100.8 120.0 34.7 95.5 146.3 170.8 196.1 46.1 103.6 222.8 84.6 93.9 109.2 0.1 0.1 0.0 0.8 0.0 0.5 0.4 0.6 1.1 0.7 0.3 0.4 1.1 0.1 1.5 0.0 3.6 2.4 0.6 0.5 0.8 0.2 1.9 1.1 0.1 0.1 0.0 0.3 0.0 0.2 0.6 2.2 0.0 2.0 0.7 4.9 4.2 1.1 3.7 3.4 0.2 2.1 2.2 0.9 1.5 1.3 0.0 0.0 23.2 2.3 7.8 0.0 1.3 2.2 1.3 2.9 2.1 0.0 37.2 2.0 0.6 34.6 5.6 3.6 5.1 0.0 8.1 1.1 0.9 8.3 0.0 0.7 6.1 0.0 1.3 2.1 1.0 2.8 1.5 0.0 0.0 0.0 0.4 2.1 0.0 0.2 1.5 3.0 0.7 31.6 1.3 0.8 0.2 0.2 0.3 13.1 0.6 4.6 69.5 57.2 9.1 1.6 16.7 3.3 1.9 9.3 2.4 CDCA7 "FLJ14736, JPO1" ENSG00000144354 "Cell division cycle associated 7" Q9BWT1 2 173354820-173368997 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.4;lymphoid tissue: 50.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 45.7;Intestinal goblet cells: 40.7;Leydig cells: 53.7;Undifferentiated cells: 124.2" "Cancer enhanced" "Detected in all" "colorectal cancer: 43.3" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "T-reg: 7.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MOLT-4: 279.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005565 Supported Nucleoplasm,Cytosol No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "HPA005565: AB_2078680" "unprognostic (1.67e-3)" "unprognostic (2.26e-1)" "unprognostic (1.21e-1)" "unprognostic (1.54e-2)" "unprognostic (2.16e-1)" "unprognostic (1.44e-2)" "prognostic unfavorable (4.20e-4)" "unprognostic (7.54e-2)" "prognostic unfavorable (5.50e-4)" "unprognostic (4.96e-2)" "unprognostic (2.83e-1)" "unprognostic (8.97e-3)" "unprognostic (0.00e+0)" "unprognostic (4.53e-3)" "unprognostic (1.96e-1)" "unprognostic (2.04e-1)" "unprognostic (2.47e-2)" 1.7 0.3 0.7 13.1 0.6 23.0 2.4 0.5 0.7 12.6 6.5 25.5 30.7 13.8 3.3 10.1 3.8 1.5 0.8 0.7 1.2 0.5 0.3 1.6 37.5 0.7 0.9 1.1 1.7 0.3 0.1 7.4 0.7 3.0 29.5 0.4 2.5 1.2 3.1 11.7 32.4 3.4 0.7 2.4 14.3 6.0 1.2 50.1 0.5 0.8 41.2 2.8 6.7 1.0 44.2 33.3 76.4 83.3 3.6 14.0 79.9 26.0 9.2 60.3 67.2 51.6 54.4 122.1 32.2 15.8 23.5 45.0 122.4 46.6 87.0 59.2 67.4 27.6 24.6 66.0 3.8 181.2 25.1 11.4 3.9 32.8 27.3 7.8 28.0 158.1 67.4 27.2 17.7 35.4 279.7 181.7 90.4 103.4 22.7 194.4 58.2 77.3 29.5 38.2 22.3 39.2 40.8 13.4 22.0 67.9 0.3 70.5 13.0 39.3 16.8 12.9 48.5 7.4 17.1 173.0 24.4 99.8 34.0 0.0 0.5 0.0 1.1 0.0 0.4 1.9 3.0 5.9 3.5 0.3 0.2 1.0 0.2 3.2 0.0 0.5 7.9 2.3 0.7 0.6 0.5 0.7 0.7 1.2 0.7 0.9 0.7 0.7 1.2 1.0 1.0 0.0 0.6 0.7 3.0 20.3 14.9 3.3 14.8 0.0 2.6 6.5 1.1 0.0 0.3 0.0 0.0 45.7 1.6 17.1 0.0 0.2 0.9 3.2 33.0 3.4 12.2 33.6 0.1 0.2 29.9 4.1 22.4 6.8 0.0 18.5 0.0 0.2 10.4 0.0 10.5 40.7 4.1 1.0 4.4 2.2 53.7 2.3 3.6 0.0 1.2 0.7 0.0 0.5 0.1 1.0 11.1 34.6 3.8 5.3 11.9 0.0 0.1 0.0 0.0 1.1 7.2 13.8 28.9 21.8 15.9 10.1 9.1 2.7 124.2 3.8 CDCA7L "JPO2, R1, RAM2" ENSG00000164649 "Cell division cycle associated 7 like" Q96GN5 7 21900899-21945903 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 51.0;Spermatogonia: 63.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 101.0;naive B-cell: 124.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 4 "olfactory bulb: 10.1" "HPA027169, HPA074623" Approved Supported Nucleoplasm,Nucleoli,Cytosol No Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Nucleoli" Cytosol "HPA027169: AB_1856058, HPA074623: " "unprognostic (5.13e-3)" "unprognostic (5.94e-2)" "unprognostic (1.91e-1)" "unprognostic (4.63e-2)" "unprognostic (2.33e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (4.36e-6)" "unprognostic (4.09e-2)" "unprognostic (2.86e-1)" "unprognostic (3.87e-2)" "unprognostic (3.22e-2)" "unprognostic (2.34e-1)" "prognostic unfavorable (1.98e-4)" "unprognostic (2.00e-1)" "unprognostic (1.60e-1)" "unprognostic (1.73e-1)" "unprognostic (2.83e-3)" 5.9 1.4 3.9 15.0 9.1 51.7 15.7 5.7 5.2 8.7 17.8 17.0 10.7 13.8 5.5 11.2 11.5 8.1 25.3 3.9 3.5 2.8 4.8 14.0 37.1 6.9 4.8 21.8 13.0 1.8 1.1 4.7 3.8 7.3 19.0 5.1 9.0 7.6 6.2 18.5 13.6 11.9 5.0 13.3 17.8 18.5 7.8 49.0 29.8 3.4 31.8 6.3 8.1 9.8 84.5 27.6 26.0 0.6 14.5 17.9 0.0 65.9 58.2 51.8 73.5 11.3 75.4 173.6 21.8 59.3 102.4 51.1 41.4 69.4 103.6 0.3 28.6 42.3 83.8 7.4 21.1 111.1 0.4 35.2 12.7 40.0 116.9 54.9 104.8 133.5 58.3 0.1 41.4 34.5 146.1 46.1 153.2 17.4 36.2 141.0 94.0 119.8 15.4 14.8 96.9 79.7 30.3 19.9 29.9 34.4 45.6 54.6 43.0 57.1 68.5 101.3 83.8 90.6 63.6 223.0 55.7 154.6 54.5 1.1 2.3 43.2 2.2 3.8 0.3 101.0 6.4 3.2 14.9 124.5 30.9 12.8 3.8 3.4 4.9 75.9 9.9 12.2 3.9 9.1 5.7 5.2 3.9 3.5 6.9 4.8 3.8 5.0 7.8 9.8 1.0 19.2 31.5 7.5 51.0 27.1 23.7 6.9 17.1 1.5 12.5 20.7 38.7 11.5 19.0 0.0 2.1 0.5 30.7 8.4 3.9 8.9 7.3 5.4 2.7 4.8 10.7 21.9 0.5 6.2 0.3 13.4 18.3 5.3 8.8 14.9 1.4 4.0 10.8 13.5 1.0 26.1 8.2 15.2 3.5 5.2 4.1 7.0 8.8 1.9 1.6 2.4 1.0 15.1 8.7 3.9 7.4 2.6 20.2 14.2 1.5 0.1 4.2 2.7 13.1 6.8 12.4 4.6 63.5 9.6 7.7 0.3 5.4 8.3 23.0 6.2 CDH11 "CAD11, OB" ENSG00000140937 "Cadherin 11" P55287 16 64943753-65126112 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 178.2;placenta: 122.2" "Cell type enhanced" "Detected in many" "Astrocytes: 93.0;Endometrial stromal cells: 125.0;Excitatory neurons: 122.2;Fibroblasts: 102.2;Microglial cells: 145.2;Oligodendrocyte precursor cells: 158.3;Oligodendrocytes: 106.3;Theca cells: 160.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 246.5;BJ hTERT+: 139.3;fHDF/TERT166: 332.3;HSkMC: 217.4;PC-3: 291.2;U-2197: 194.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013072 Enhanced NA Yes 4800000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB013072: AB_2533068" "unprognostic (1.77e-1)" "unprognostic (1.51e-1)" "unprognostic (1.50e-1)" "unprognostic (6.93e-2)" "unprognostic (6.00e-2)" "unprognostic (1.02e-1)" "unprognostic (6.96e-2)" "unprognostic (1.28e-1)" "unprognostic (2.09e-1)" "unprognostic (2.30e-2)" "unprognostic (3.74e-2)" "unprognostic (6.75e-2)" "prognostic unfavorable (2.48e-9)" "unprognostic (1.43e-3)" "unprognostic (3.20e-2)" "unprognostic (1.26e-1)" "unprognostic (5.07e-3)" 15.1 8.6 12.4 25.7 27.9 0.3 10.7 10.8 15.8 57.7 13.8 11.4 7.0 52.8 9.5 7.4 12.5 58.6 10.2 19.2 21.4 10.2 1.8 45.6 17.5 17.1 24.1 178.2 3.4 2.6 10.4 122.2 17.3 20.0 12.2 14.0 12.7 24.3 2.6 10.9 8.9 54.3 21.1 89.3 11.8 8.0 19.3 3.7 8.1 3.1 13.0 47.6 13.6 21.4 0.2 0.0 51.4 0.1 35.7 77.5 0.3 246.5 139.3 61.0 34.5 4.6 0.2 0.0 0.0 332.3 0.0 0.1 0.1 1.7 43.4 0.0 2.1 0.0 1.4 0.0 29.7 0.0 14.4 217.4 0.1 74.7 14.9 0.0 17.4 0.0 0.0 0.0 33.1 0.3 0.1 0.3 19.2 37.4 291.2 0.8 38.0 0.0 0.0 0.0 0.8 36.0 0.1 0.3 0.2 64.5 0.3 0.1 0.0 124.4 17.2 194.0 70.1 0.0 0.0 0.1 21.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 27.9 10.8 15.8 19.2 21.4 17.1 24.1 17.3 21.1 19.3 21.4 11.4 3.2 0.0 93.0 0.1 3.8 1.0 7.9 0.0 19.9 1.0 7.4 3.1 1.5 3.3 0.0 0.0 2.6 0.2 0.1 0.0 0.1 2.7 3.9 125.0 17.8 0.0 2.7 122.2 0.0 2.3 102.2 0.5 2.7 0.0 60.0 68.9 0.0 4.7 0.0 67.6 0.6 0.0 0.6 6.9 4.2 52.5 0.9 5.4 145.2 0.0 41.9 0.0 158.3 106.3 0.8 0.0 77.5 0.0 1.6 0.0 1.4 0.4 2.1 26.3 12.8 38.0 1.7 1.1 0.5 3.1 5.6 1.1 160.2 0.3 0.5 CDH18 "CDH14, EY-CADHERIN" ENSG00000145526 "Cadherin 18" Q13634 5 19471296-20575873 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 35.9" "Group enriched" "Detected in some" 5 "Excitatory neurons: 923.8;Inhibitory neurons: 694.3;Oligodendrocyte precursor cells: 248.3" "Cancer enhanced" "Detected in some" "ovarian cancer: 0.7" "Region enhanced" "Detected in many" "cerebellum: 35.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 4.4;GAMG: 7.6;hTERT-RPE1: 4.2;U-2 OS: 6.8;U-2197: 6.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014416 Uncertain "Intracellular and membrane" NA Yes "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA014416: AB_2668996" "unprognostic (1.57e-1)" "unprognostic (1.68e-1)" "unprognostic (5.26e-7)" "unprognostic (6.36e-2)" "unprognostic (1.10e-1)" "unprognostic (1.44e-2)" "unprognostic (1.20e-1)" "unprognostic (8.78e-2)" "unprognostic (3.30e-2)" "unprognostic (1.51e-2)" "unprognostic (8.69e-2)" "unprognostic (1.76e-2)" 0.0 4.6 2.7 0.0 6.8 0.0 0.0 35.9 12.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 8.4 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.9 4.0 0.0 5.7 0.0 0.0 2.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 1.8 1.9 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.2 0.0 0.3 0.0 0.6 2.9 2.5 0.1 1.6 0.1 0.5 0.0 0.0 0.0 4.4 0.0 7.6 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 1.7 4.2 0.0 0.0 0.1 0.5 0.3 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.9 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 6.8 6.2 0.0 1.7 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 6.8 35.9 12.3 6.1 8.4 0.0 0.4 5.7 0.0 1.9 1.9 0.0 0.0 0.0 22.9 0.0 0.0 1.3 0.0 0.0 6.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 109.9 0.0 0.0 0.0 0.0 0.0 923.8 0.0 5.3 0.3 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.0 694.3 0.0 0.0 0.0 0.0 19.2 0.3 0.1 0.0 17.8 0.0 0.2 0.0 248.3 15.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.0 1.6 0.0 0.1 0.1 6.4 3.4 0.0 0.0 0.3 0.0 0.3 0.0 0.0 CDKN3 "CDI1, KAP" ENSG00000100526 "Cyclin dependent kinase inhibitor 3" Q16667 14 54396849-54420218 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 207.0" "Cell type enhanced" "Detected in many" "Early spermatids: 2630.9;Late spermatids: 659.4;Spermatocytes: 606.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 18.8" "Group enriched" "Detected in all" 6 "NK-cells: 6.4;T-cells: 18.8" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005285, HPA039311, HPA058874" Enhanced Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "CAB005285: AB_2078884, HPA039311: , HPA058874: AB_2683842" "unprognostic (3.46e-2)" "unprognostic (9.95e-2)" "unprognostic (5.79e-2)" "unprognostic (6.78e-3)" "unprognostic (2.73e-1)" "unprognostic (6.08e-2)" "unprognostic (1.51e-3)" "prognostic unfavorable (4.52e-4)" "unprognostic (2.50e-3)" "unprognostic (2.85e-3)" "prognostic unfavorable (7.46e-4)" "unprognostic (5.89e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.71e-1)" "unprognostic (7.30e-2)" "unprognostic (7.92e-2)" "unprognostic (4.31e-2)" 3.4 1.6 2.8 12.2 2.7 43.4 3.4 5.0 4.2 2.2 3.4 13.9 12.4 2.8 0.4 10.2 1.3 2.9 5.3 2.9 3.1 2.0 2.4 2.1 28.4 2.5 2.7 1.3 1.1 0.5 1.6 6.7 3.3 1.6 16.9 2.6 3.3 0.7 3.0 5.9 12.6 7.4 2.1 4.9 5.0 207.0 3.5 30.9 1.7 4.1 30.0 5.8 4.1 2.6 276.7 102.5 74.0 78.2 12.5 15.3 46.5 63.1 97.0 135.8 146.9 81.8 136.5 139.9 44.4 96.7 135.9 195.9 114.6 78.3 245.6 169.5 59.3 65.8 69.0 126.8 10.1 86.2 47.6 5.4 4.9 84.3 138.3 44.4 88.4 129.8 36.1 162.2 159.8 186.9 118.1 67.9 27.9 254.7 216.4 72.7 66.6 29.7 70.5 56.9 30.6 42.0 118.7 67.4 52.5 54.6 142.9 69.4 33.0 59.2 195.8 91.7 155.0 38.6 47.4 91.4 98.6 120.4 110.9 0.0 1.3 1.3 1.6 1.7 0.7 2.1 5.5 4.8 1.8 0.9 2.9 2.3 1.0 6.4 1.2 1.5 18.8 3.1 2.8 2.7 5.0 4.2 2.9 3.1 2.5 2.7 3.3 2.1 3.5 2.6 1.4 0.0 0.0 0.7 10.5 9.3 4.3 9.7 4.6 3.2 6.4 11.6 9.7 0.0 2.4 1.8 2.1 42.6 2.7 7.3 0.0 3.5 2630.9 2.7 3.5 6.8 7.8 125.5 2.5 2.4 35.0 10.2 9.2 3.5 7.0 31.3 6.1 3.1 37.7 5.0 3.9 17.9 4.1 9.8 8.8 659.4 21.5 8.9 1.8 1.0 2.9 1.7 0.0 0.0 0.2 1.9 7.2 10.5 41.0 4.0 3.4 2.8 0.2 2.9 0.0 3.0 20.5 606.9 39.8 22.5 6.5 4.1 8.3 3.9 31.2 5.3 CDT1 "DUP, RIS2" ENSG00000167513 "Chromatin licensing and DNA replication factor 1" Q9H211 16 88803789-88809258 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" "Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "bone marrow: 38.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 51.4;Erythroid cells: 71.3;Extravillous trophoblasts: 92.0;Spermatogonia: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NB-4: 149.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA017224 Approved Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA017224: AB_1846468" "unprognostic (1.33e-1)" "unprognostic (2.04e-2)" "unprognostic (7.32e-2)" "unprognostic (2.67e-1)" "unprognostic (4.34e-1)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.12e-6)" "unprognostic (3.44e-3)" "unprognostic (2.81e-2)" "unprognostic (4.59e-2)" "unprognostic (1.21e-1)" "unprognostic (9.34e-2)" "prognostic unfavorable (2.69e-6)" "unprognostic (7.72e-3)" "unprognostic (5.79e-2)" "unprognostic (2.80e-2)" "unprognostic (8.54e-2)" 0.7 0.8 0.8 3.8 1.2 38.5 0.7 2.5 1.3 1.7 0.0 3.3 4.1 0.5 0.2 6.7 0.5 0.2 0.5 0.8 2.3 0.7 1.0 1.3 4.8 2.2 1.1 0.4 0.6 1.3 2.1 2.8 1.9 0.7 1.6 0.4 1.1 0.2 0.1 3.6 3.9 0.6 0.7 3.1 2.4 3.5 1.1 8.7 0.6 0.0 3.3 0.5 2.3 1.0 33.6 34.5 16.5 25.3 0.7 3.4 64.2 24.1 6.6 19.4 12.0 79.3 33.8 51.4 24.2 5.5 12.7 46.0 21.6 17.7 6.2 18.2 92.1 51.8 28.8 59.9 0.3 28.8 21.5 1.8 1.4 19.8 4.4 1.6 5.9 60.9 80.8 18.4 7.6 90.6 109.3 149.4 41.8 12.2 31.6 120.3 22.9 42.4 4.3 23.8 36.6 26.2 44.4 13.1 16.9 7.4 39.0 55.9 5.9 24.6 42.6 37.2 35.4 61.4 55.7 73.6 19.3 71.9 31.6 0.2 0.1 0.9 0.3 0.0 0.0 0.1 0.1 0.2 0.3 0.2 0.1 0.1 0.7 0.4 0.1 0.1 0.7 0.2 0.8 1.2 2.5 1.3 0.8 2.3 2.2 1.1 1.9 0.7 1.1 1.0 0.4 0.0 1.1 0.7 4.9 11.2 4.3 1.4 7.4 0.7 5.4 7.5 2.2 1.5 1.7 1.8 0.0 51.4 2.2 12.7 1.9 1.1 0.4 1.4 1.4 2.2 2.4 71.3 0.2 0.0 92.0 5.2 9.2 2.2 0.0 29.0 0.4 1.0 19.5 0.0 0.8 16.1 4.1 5.6 5.5 1.2 0.3 2.8 1.8 0.0 1.9 1.5 4.1 0.0 0.6 0.6 2.3 0.4 23.1 2.2 2.0 1.6 2.1 1.9 0.0 2.1 3.4 6.6 37.1 10.8 7.1 24.8 5.4 5.7 30.1 4.4 CENPF hcp-1 ENSG00000117724 "Centromere protein F" P49454 1 214603195-214664571 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, DNA synthesis, Mitosis, Myogenesis" "Developmental protein" "Cancer-related genes, Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.8;lymphoid tissue: 33.0" "Cell type enhanced" "Detected in many" "Early spermatids: 84.4;Erythroid cells: 268.7;Extravillous trophoblasts: 78.8;Granulosa cells: 165.8;Spermatocytes: 107.5;Spermatogonia: 107.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "HPA052382, HPA064308, CAB070134" Enhanced Supported Nucleoplasm Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB070134: AB_2229328, HPA052382: AB_2681808, HPA064308: AB_2732711" "unprognostic (2.80e-1)" "unprognostic (2.16e-1)" "unprognostic (2.65e-1)" "unprognostic (5.30e-2)" "unprognostic (1.73e-1)" "unprognostic (2.40e-2)" "prognostic unfavorable (2.29e-5)" "unprognostic (1.13e-2)" "unprognostic (2.58e-3)" "unprognostic (1.11e-1)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.58e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.92e-2)" "unprognostic (1.71e-1)" "unprognostic (1.89e-2)" "unprognostic (4.12e-1)" 0.8 1.1 0.1 4.4 0.1 28.8 1.8 0.0 0.3 1.3 0.5 5.8 6.1 1.8 0.1 8.6 0.6 0.7 0.4 0.3 0.0 0.4 0.9 0.9 8.5 0.3 0.5 0.7 0.3 0.2 0.1 3.1 0.3 0.5 5.7 1.0 1.4 0.1 0.2 6.2 4.3 2.5 0.2 2.4 2.6 10.5 0.5 33.0 0.4 0.6 10.0 1.4 2.6 0.3 123.7 68.4 144.3 75.8 5.4 7.2 56.3 74.6 30.3 43.9 42.8 54.6 74.1 116.3 43.1 41.7 39.8 74.7 89.9 49.2 74.1 102.6 56.6 96.0 111.4 78.6 0.8 137.0 50.5 2.7 3.8 63.3 72.3 12.7 46.9 52.6 88.4 68.0 79.4 47.0 81.5 54.3 127.9 36.8 30.0 85.7 203.7 38.6 43.2 30.3 67.4 91.2 100.7 66.2 38.9 76.2 79.1 51.9 61.7 78.9 92.2 66.2 155.9 51.6 60.7 108.7 34.4 96.7 71.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.3 0.3 0.0 0.3 0.5 0.3 0.2 0.5 0.3 3.0 0.0 3.1 0.0 11.5 9.3 2.8 11.2 3.4 4.7 10.0 6.7 1.9 1.5 9.9 0.0 0.0 53.3 10.8 19.1 0.0 2.0 84.4 30.1 19.3 12.4 0.0 268.7 1.3 0.4 78.8 19.0 32.1 25.2 1.3 165.8 8.9 2.6 32.2 1.7 0.8 20.1 14.2 16.6 6.6 19.8 1.2 16.2 1.8 1.0 0.7 1.4 5.2 0.0 0.1 0.5 1.1 3.0 25.9 2.3 2.1 0.1 16.7 3.1 0.0 8.3 23.9 107.5 107.1 44.6 5.5 5.1 23.3 11.7 41.3 3.7 CENPQ "C6orf139, CENP-Q, FLJ10545" ENSG00000031691 "Centromere protein Q" Q7L2Z9 6 49463370-49493107 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatogonia: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029043, HPA046634, HPA054965" Approved Supported Nucleoplasm NA Yes "Cluster 37: B-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA029043: AB_2672881, HPA046634: AB_2679728, HPA054965: AB_2682653" "unprognostic (7.39e-2)" "unprognostic (7.33e-2)" "unprognostic (1.37e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (2.49e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (2.21e-5)" "unprognostic (1.36e-1)" "unprognostic (1.76e-2)" "prognostic favorable (6.26e-4)" "unprognostic (2.89e-1)" "unprognostic (8.19e-2)" "unprognostic (1.48e-3)" "unprognostic (8.93e-2)" "unprognostic (7.47e-2)" "unprognostic (2.74e-3)" "unprognostic (2.56e-1)" 4.8 4.7 4.7 5.4 5.8 4.9 5.4 5.8 6.9 3.1 3.8 3.9 2.8 4.7 3.0 4.3 4.0 3.5 6.4 4.2 5.1 3.8 4.4 3.8 7.0 5.8 5.2 6.2 2.5 3.6 2.3 5.9 6.0 4.5 4.7 4.2 2.8 3.3 5.0 4.0 3.3 4.4 5.3 4.7 3.8 6.0 4.8 9.4 3.7 8.4 8.4 3.7 3.3 7.6 35.3 9.7 30.1 18.9 8.0 12.4 26.4 44.6 25.5 41.9 58.4 11.9 13.8 23.7 21.7 12.7 32.8 12.5 15.8 16.2 61.6 25.9 22.0 17.5 14.6 19.2 3.4 37.4 21.2 5.7 8.7 51.5 17.9 10.7 15.5 20.4 27.3 22.9 31.4 10.2 26.4 17.6 18.8 30.6 8.7 18.8 35.6 25.8 12.3 14.3 16.2 16.0 21.0 12.4 23.9 29.6 15.9 33.8 9.2 32.3 25.2 25.7 40.4 10.4 28.9 21.4 21.9 27.8 32.0 2.2 1.2 4.1 2.0 1.4 2.0 4.4 2.1 2.3 1.3 4.5 2.3 2.3 0.9 2.4 1.8 2.7 3.2 1.2 4.7 5.8 5.8 6.9 4.2 5.1 5.8 5.2 6.0 5.3 4.8 7.6 8.6 0.0 2.7 7.2 9.5 8.7 9.9 10.4 8.6 6.3 4.1 4.7 6.2 4.3 5.2 7.3 2.1 17.3 8.7 4.2 7.9 7.8 1.3 8.8 5.6 8.0 2.4 5.9 3.0 7.9 30.8 9.3 6.6 5.4 4.5 6.3 14.3 3.4 10.1 6.7 3.1 3.7 2.0 11.4 6.0 2.3 8.7 5.9 3.6 11.2 7.6 14.5 13.4 6.6 13.5 7.8 8.0 10.9 7.5 5.4 1.7 4.4 9.4 5.1 6.6 15.2 6.5 17.7 34.6 6.5 7.0 12.4 5.9 4.2 5.9 6.2 CEP55 "C10orf3, CT111, FLJ10540" ENSG00000138180 "Centrosomal protein 55" Q53EZ4 10 93496612-93529092 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 27.4;testis: 21.7" "Cell type enhanced" "Detected in many" "Early spermatids: 29.4;Extravillous trophoblasts: 17.1;Granulosa cells: 19.8;Spermatocytes: 77.3;Spermatogonia: 17.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 8 "T-reg: 1.3" "Lineage enriched" "Detected in single" 14 "T-cells: 1.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA023430 Approved Approved "Plasma membrane,Midbody,Centriolar satellite" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Centriolar satellite" Midbody "HPA023430: AB_10960212" "unprognostic (9.85e-2)" "unprognostic (1.12e-2)" "unprognostic (1.04e-1)" "unprognostic (1.29e-1)" "unprognostic (5.15e-2)" "unprognostic (4.26e-2)" "prognostic unfavorable (3.20e-9)" "prognostic unfavorable (1.45e-4)" "unprognostic (1.50e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.66e-5)" "unprognostic (3.99e-2)" "prognostic unfavorable (0.00e+0)" "prognostic favorable (3.15e-4)" "unprognostic (7.86e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" 1.3 0.6 0.0 7.6 0.0 5.0 1.4 0.0 0.2 1.7 0.0 7.0 6.7 1.4 0.1 7.3 0.4 1.4 0.3 0.0 0.1 0.3 0.6 1.3 14.7 0.1 0.3 0.2 0.2 0.2 0.3 3.5 0.2 0.3 8.8 0.0 1.2 0.3 0.1 4.5 6.3 5.2 0.0 2.4 4.6 21.7 0.4 27.4 0.5 0.2 15.5 3.1 2.3 0.1 208.5 81.5 53.0 67.7 5.8 12.0 29.6 112.4 78.2 103.5 106.4 87.2 108.6 55.4 48.2 72.8 69.6 115.4 64.8 54.8 123.4 167.2 33.7 21.0 49.2 29.9 0.6 36.3 46.3 2.8 3.8 110.6 133.5 30.7 97.1 89.9 19.3 101.8 118.5 48.3 96.3 54.8 20.9 64.2 58.8 41.3 86.9 30.3 47.1 25.5 21.7 30.7 86.3 26.3 64.9 40.1 68.9 36.4 61.4 65.3 90.6 90.5 186.7 45.1 66.1 66.8 51.0 134.8 59.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.3 0.2 0.0 0.4 0.1 0.2 0.0 1.3 0.0 2.7 3.6 0.9 1.9 0.0 0.0 1.8 2.0 0.4 2.8 0.2 0.0 0.0 7.7 0.9 3.3 0.0 0.6 29.4 1.7 2.0 1.5 0.0 2.5 0.5 0.2 17.1 2.3 8.2 3.6 0.0 19.8 2.2 0.3 12.9 0.0 0.3 4.5 4.1 7.0 5.1 8.2 0.3 5.1 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.3 0.0 0.4 14.8 1.1 0.4 0.0 0.2 0.0 0.0 0.5 4.5 77.3 17.3 16.1 1.3 1.5 4.3 1.6 7.9 1.7 CHAF1A "CAF-1, CAF1, CAF1B, CAF1P150, MGC71229, P150" ENSG00000167670 "Chromatin assembly factor 1 subunit A" Q13111 19 4402640-4445018 "Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, DNA replication" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 31.4" "Cell type enhanced" "Detected in many" "Erythroid cells: 50.3;Spermatocytes: 94.3;Spermatogonia: 103.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 15.7" "Group enriched" "Detected in many" 4 "dendritic cells: 15.7;granulocytes: 4.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB015186 Enhanced Supported Nucleoplasm,Cytosol NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "CAB015186: AB_628065" "unprognostic (1.91e-1)" "prognostic favorable (8.22e-5)" "unprognostic (2.49e-1)" "unprognostic (4.71e-2)" "unprognostic (2.06e-1)" "unprognostic (1.89e-3)" "unprognostic (5.30e-3)" "unprognostic (8.78e-2)" "unprognostic (2.06e-2)" "unprognostic (2.12e-2)" "unprognostic (2.46e-2)" "unprognostic (1.16e-1)" "unprognostic (8.54e-2)" "prognostic favorable (4.15e-6)" "unprognostic (1.71e-1)" "unprognostic (2.11e-3)" "unprognostic (4.03e-2)" 4.9 4.4 3.5 9.7 3.0 31.4 4.8 5.6 6.6 4.7 1.3 6.9 6.5 3.9 2.0 10.2 4.0 2.7 3.9 3.7 3.0 2.4 4.1 4.0 13.4 3.4 3.1 3.7 3.9 3.3 3.7 6.2 3.0 5.8 6.6 3.4 5.5 3.0 12.2 10.8 6.7 4.1 2.4 6.9 5.1 14.5 3.1 16.3 2.9 4.1 10.5 4.7 5.6 4.1 65.8 44.0 71.8 45.3 7.0 8.5 36.7 61.2 24.8 50.5 56.7 53.5 22.8 100.4 24.7 19.6 28.6 50.3 61.6 41.5 59.8 58.1 67.2 62.9 69.4 42.7 3.5 73.7 48.8 4.8 8.6 41.5 17.7 9.4 24.0 54.9 76.8 88.0 31.3 37.8 119.2 40.7 80.1 33.5 35.6 87.2 56.8 57.2 13.1 76.7 50.6 39.2 41.6 29.1 24.5 45.2 25.7 53.9 17.5 41.3 35.9 71.1 74.9 43.7 71.0 96.3 34.7 92.8 49.9 3.8 2.3 4.7 0.5 2.3 0.4 1.6 0.6 0.1 2.1 1.0 0.5 0.4 1.2 1.2 0.4 15.7 0.9 0.9 3.5 3.0 5.6 6.6 3.7 3.0 3.4 3.1 3.0 2.4 3.1 4.1 2.3 0.0 3.9 2.0 12.5 9.7 4.6 3.5 6.2 12.1 5.1 3.6 5.7 1.5 2.6 5.5 2.1 25.3 17.3 13.9 1.9 8.5 6.7 5.3 4.2 4.6 1.8 50.3 4.1 6.7 37.9 6.1 10.7 6.5 2.5 19.3 3.3 4.8 12.1 1.7 3.6 10.7 0.0 4.8 21.4 6.7 3.1 11.8 1.8 1.9 11.5 5.2 5.2 2.5 2.9 6.8 1.7 3.8 32.5 4.1 4.6 1.8 5.0 8.4 32.9 5.7 5.5 94.3 103.8 18.7 14.9 14.6 7.7 9.4 14.6 5.9 CHKA "CHK, CKI" ENSG00000110721 "Choline kinase alpha" P35790 11 68052859-68121444 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 179.6;Early spermatids: 357.3;Late spermatids: 267.3;Oligodendrocytes: 203.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 6.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "SK-MEL-30: 183.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024153, CAB072803" Approved Approved "Endoplasmic reticulum" NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 34: Spermatids - Unknown function" "Endoplasmic reticulum" "CAB072803: , HPA024153: AB_1846664" "unprognostic (5.16e-2)" "unprognostic (1.46e-1)" "unprognostic (2.52e-1)" "unprognostic (2.51e-1)" "unprognostic (2.66e-1)" "unprognostic (2.81e-1)" "prognostic unfavorable (7.75e-4)" "unprognostic (2.36e-3)" "unprognostic (1.66e-3)" "unprognostic (1.67e-2)" "unprognostic (1.33e-1)" "unprognostic (1.99e-1)" "unprognostic (5.97e-3)" "unprognostic (5.00e-2)" "unprognostic (6.06e-2)" "unprognostic (1.82e-1)" "unprognostic (4.73e-2)" 17.0 35.8 49.4 7.1 54.2 33.8 20.9 51.8 57.8 18.3 53.5 25.8 21.6 12.2 20.5 6.2 13.2 10.3 14.5 49.5 50.7 23.9 43.3 17.8 9.0 56.6 53.6 20.1 38.0 8.0 21.6 5.2 61.5 31.0 12.8 21.1 44.9 16.4 8.3 8.7 23.1 5.4 51.0 30.0 40.0 75.5 54.0 5.7 43.6 4.5 5.5 19.4 9.3 71.7 25.6 21.3 24.2 24.1 8.0 6.1 24.5 7.7 13.6 22.5 14.4 92.2 70.5 18.9 27.4 12.4 23.2 16.2 34.4 5.6 18.5 8.7 12.1 23.8 29.6 106.9 22.9 25.6 12.5 11.0 9.4 10.0 4.8 12.3 12.7 11.9 23.1 34.7 12.0 19.4 14.6 68.4 40.1 83.2 14.2 21.3 26.1 54.6 18.1 27.3 17.9 19.6 14.9 74.6 183.8 19.9 31.6 34.4 7.3 14.2 16.3 32.4 10.4 37.0 42.5 34.4 14.6 32.8 13.0 0.0 0.8 6.1 0.1 1.5 0.0 0.7 0.1 0.2 0.9 0.3 0.4 0.2 0.4 1.1 0.9 0.7 0.2 0.2 49.4 54.2 51.8 57.8 49.5 50.7 56.6 53.6 61.5 51.0 54.0 71.7 27.2 44.8 36.6 179.6 10.1 15.8 16.6 6.5 18.2 10.6 49.4 35.7 3.6 35.8 20.2 3.7 33.3 8.2 14.2 48.1 13.7 9.6 357.3 42.7 16.2 13.6 28.1 6.7 89.0 19.3 3.4 9.2 37.2 59.0 19.0 23.4 11.7 19.8 17.6 57.2 63.2 16.3 0.0 28.5 19.4 267.3 6.2 31.0 23.2 59.0 8.5 21.4 2.1 100.0 203.5 18.4 18.0 2.6 10.1 17.3 21.6 4.6 23.1 28.4 0.0 9.6 9.8 121.9 20.7 9.2 10.4 13.0 8.2 16.9 31.7 39.2 CKAP5 "ch-TOG, KIAA0097, TOG, TOGp" ENSG00000175216 "Cytoskeleton associated protein 5" Q14008 11 46743048-46846308 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 119.7;Spermatocytes: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039377, HPA040375" Supported Approved "Nucleoli,Nucleoli rim,Plasma membrane,Centrosome" NA Yes 360000 "Cluster 27: Non-specific - Gene expression" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Centrosome" "Nucleoli, Nucleoli rim" "HPA039377: AB_10805477, HPA040375: AB_10794739" "unprognostic (8.00e-2)" "unprognostic (7.35e-2)" "unprognostic (2.35e-1)" "unprognostic (4.12e-2)" "unprognostic (1.91e-1)" "unprognostic (2.08e-2)" "prognostic unfavorable (1.03e-6)" "unprognostic (6.09e-2)" "unprognostic (1.12e-2)" "unprognostic (2.21e-2)" "unprognostic (4.30e-3)" "unprognostic (3.77e-2)" "unprognostic (2.03e-1)" "unprognostic (2.71e-1)" "unprognostic (1.12e-1)" "unprognostic (3.48e-1)" "unprognostic (4.69e-2)" 12.8 30.7 15.9 15.1 19.5 25.9 14.9 30.8 24.3 11.7 5.2 18.5 12.6 15.7 12.2 13.0 11.5 12.2 21.3 21.4 18.0 11.5 45.5 10.4 18.4 21.0 17.4 27.8 9.0 21.2 12.5 17.3 22.9 15.9 17.2 57.0 9.1 13.2 37.8 13.7 12.3 19.3 17.5 11.9 16.1 33.0 20.2 36.4 9.6 28.8 18.5 13.5 10.8 24.6 104.7 95.8 212.6 90.8 48.7 73.0 48.3 117.1 69.4 107.8 114.6 76.8 33.3 104.5 41.0 76.0 117.0 116.2 144.0 62.7 134.3 102.0 107.6 176.6 80.2 78.4 35.0 139.6 76.7 37.0 34.0 60.3 125.6 56.1 79.3 97.9 129.5 103.8 89.2 71.2 127.9 39.2 114.7 78.8 73.0 131.2 210.0 98.3 34.7 63.3 96.8 83.9 149.8 56.9 57.3 88.9 103.9 39.1 64.0 106.2 92.9 180.8 176.2 59.2 137.3 158.6 66.5 64.9 105.9 4.6 4.2 4.6 6.1 6.2 5.9 6.5 4.5 6.9 6.1 6.2 5.4 5.8 0.7 8.6 6.2 3.9 5.6 3.1 15.9 19.5 30.8 24.3 21.4 18.0 21.0 17.4 22.9 17.5 20.2 24.6 13.4 25.6 23.6 32.3 17.4 8.5 11.0 17.9 16.5 19.3 11.6 12.3 65.2 12.8 18.8 9.2 37.5 19.4 11.2 13.3 9.8 12.2 119.7 19.7 21.0 16.5 12.1 32.6 61.9 7.8 15.0 27.8 29.0 18.8 37.9 55.5 11.7 8.1 18.7 13.5 63.1 16.9 16.2 17.6 5.6 50.7 19.6 19.6 7.2 30.9 16.5 16.2 16.5 32.6 51.7 13.7 15.2 29.0 26.4 14.2 9.1 9.3 30.7 25.6 19.7 18.0 21.4 107.4 59.3 24.3 11.6 11.5 16.1 83.3 19.8 9.7 CKS2 ENSG00000123975 "CDC28 protein kinase regulatory subunit 2" P33552 9 89311195-89316703 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 177.3;testis: 186.3" "Cell type enhanced" "Detected in many" "Langerhans cells: 474.6;Spermatocytes: 692.7;Spermatogonia: 503.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 187.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003424, HPA030762" Approved Approved Nucleoplasm,Vesicles,Mitochondria,Cytosol NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Mitochondria, Cytosol" "Nucleoplasm, Vesicles" "HPA003424: AB_2666948, HPA030762: AB_10670044" "unprognostic (8.30e-2)" "unprognostic (3.00e-1)" "unprognostic (1.50e-2)" "unprognostic (2.80e-2)" "unprognostic (2.96e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (2.51e-6)" "unprognostic (3.57e-3)" "unprognostic (7.04e-2)" "unprognostic (1.34e-2)" "prognostic unfavorable (6.85e-4)" "unprognostic (1.24e-2)" "prognostic unfavorable (1.78e-5)" "unprognostic (2.13e-3)" "unprognostic (1.44e-1)" "unprognostic (2.84e-1)" "unprognostic (1.84e-1)" 13.6 82.9 9.6 38.5 10.0 177.3 20.1 11.9 26.9 10.1 11.8 44.1 43.3 13.0 8.8 53.2 12.1 18.7 10.3 12.7 10.3 35.6 31.2 24.0 102.8 10.5 10.1 9.4 4.2 19.8 4.8 44.3 11.0 15.0 41.0 27.9 10.8 17.8 9.4 19.9 33.1 17.6 10.6 32.6 20.4 186.3 10.8 121.1 12.8 4.8 84.7 26.5 19.9 11.3 685.9 570.1 342.6 230.6 98.7 89.1 249.5 396.1 211.4 428.1 340.0 236.1 328.6 504.9 228.4 149.1 761.4 466.5 415.5 305.1 488.2 398.1 335.5 257.5 378.9 637.5 42.4 531.7 281.2 33.0 69.2 307.2 269.1 162.9 403.2 409.1 313.2 430.6 556.0 509.1 420.7 928.3 501.6 795.5 521.5 358.4 376.4 303.7 342.8 153.5 288.4 171.7 328.7 314.9 324.5 318.4 379.7 304.2 231.4 184.1 350.3 449.6 588.2 345.9 759.2 415.3 271.3 303.1 268.5 40.8 19.5 44.1 22.6 26.5 25.3 61.3 30.4 21.9 22.5 44.7 16.3 21.8 14.5 40.9 14.8 187.9 62.7 23.6 9.6 10.0 11.9 26.9 12.7 10.3 10.5 10.1 11.0 10.6 10.8 11.3 138.6 38.5 103.9 0.3 175.7 280.2 92.1 126.1 259.0 4.1 107.2 169.0 61.3 5.7 49.9 14.7 0.0 231.1 201.1 79.4 23.5 20.1 37.3 149.7 66.4 66.1 122.3 266.9 1.2 11.2 379.4 63.1 74.9 250.2 145.0 144.7 29.3 25.0 184.6 0.0 1.9 164.9 111.9 40.5 474.6 77.0 25.7 164.3 140.5 1.9 31.0 26.1 28.8 1.0 1.1 31.1 67.1 16.6 89.3 72.1 37.6 209.7 32.8 7.3 46.0 75.2 206.5 692.7 503.6 197.5 299.1 199.5 156.0 70.3 162.7 102.1 CLSPN ENSG00000092853 Claspin Q9HAW4 1 35720218-35769978 "Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.3;lymphoid tissue: 7.9;retina: 6.8;testis: 5.7" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 101.0;Spermatocytes: 281.1;Spermatogonia: 263.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Region enriched" "Detected in some" 6 "basal ganglia: 7.8" "Low region specificity" "Detected in many" "HPA026305, HPA026312" Enhanced "Nucleoplasm,Golgi apparatus" Yes Yes "Cluster 17: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Golgi apparatus" "HPA026305: AB_2671833, HPA026312: AB_2671837" "unprognostic (4.75e-2)" "unprognostic (1.01e-1)" "unprognostic (9.64e-3)" "unprognostic (3.54e-2)" "unprognostic (6.82e-2)" "unprognostic (1.62e-2)" "unprognostic (1.18e-6)" "unprognostic (3.99e-3)" "unprognostic (2.08e-3)" "unprognostic (1.63e-2)" "unprognostic (8.71e-6)" "unprognostic (3.23e-2)" "unprognostic (7.61e-6)" "prognostic favorable (4.92e-4)" "unprognostic (5.12e-1)" "unprognostic (1.73e-1)" "unprognostic (1.29e-1)" 0.5 0.2 0.7 3.2 0.6 11.3 0.5 0.6 1.4 0.2 0.4 1.4 1.0 0.4 0.7 0.9 0.2 0.3 0.1 1.3 0.3 0.2 0.5 0.4 4.9 0.4 0.4 0.1 0.1 0.2 0.0 1.5 0.6 0.2 2.0 6.8 0.2 0.1 0.6 1.2 1.0 0.9 0.2 1.3 0.9 5.7 0.6 7.9 0.2 0.0 5.2 0.6 0.4 0.9 22.0 17.5 37.8 19.9 2.6 4.8 14.1 43.6 12.0 31.0 41.3 27.9 19.6 45.7 13.9 11.8 22.7 21.4 37.1 14.9 48.1 31.6 16.8 64.5 38.1 12.6 0.1 54.0 36.8 1.0 0.6 53.8 3.7 3.7 16.9 27.1 44.2 30.8 30.3 14.1 56.9 13.1 36.0 14.9 12.2 36.0 57.0 13.8 6.4 35.3 14.0 16.2 37.7 11.6 7.4 25.6 10.0 21.1 12.5 44.6 33.8 27.6 49.3 11.1 29.1 47.1 14.1 37.4 37.0 1.1 0.3 0.3 0.3 0.2 0.1 0.1 0.2 0.2 0.2 0.3 0.1 0.2 1.0 0.5 0.2 0.2 0.3 0.3 0.7 0.6 0.6 1.4 1.3 0.3 0.4 0.4 0.6 0.2 0.6 0.9 2.6 0.0 0.5 0.3 6.5 5.6 5.7 4.4 1.2 9.4 2.9 3.8 1.4 2.8 2.7 0.0 12.5 19.7 4.6 12.8 0.0 1.6 7.9 1.0 3.6 3.6 1.2 55.6 1.6 0.6 41.1 5.2 4.6 3.3 1.3 12.0 2.2 0.4 16.9 1.7 1.5 9.4 2.0 3.0 8.2 6.1 2.5 5.8 3.6 0.0 9.1 9.4 4.1 0.0 0.6 1.4 9.5 0.4 32.5 1.8 0.4 0.2 0.0 101.0 6.6 5.3 8.7 281.1 263.3 5.8 2.0 10.4 7.2 1.2 12.0 3.9 CNTRL "CEP1, CEP110" ENSG00000119397 Centriolin Q7Z7A1 9 121074753-121177610 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 28.0;testis: 35.3" "Cell type enhanced" "Detected in many" "Early spermatids: 131.7;Spermatocytes: 385.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HL-60: 81.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020468, HPA020480, HPA051583" Approved Approved "Centriolar satellite,Centrosome,Cytosol" NA Yes "Cluster 6: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Centrosome, Cytosol" "Centriolar satellite" "HPA020468: AB_2670455, HPA020480: AB_2670457, HPA051583: AB_2681542" "unprognostic (4.33e-3)" "unprognostic (2.89e-3)" "unprognostic (2.09e-2)" "unprognostic (7.97e-2)" "unprognostic (1.17e-2)" "prognostic favorable (9.21e-5)" "unprognostic (1.05e-2)" "unprognostic (3.22e-3)" "unprognostic (3.74e-3)" "unprognostic (2.02e-1)" "unprognostic (1.78e-2)" "unprognostic (5.47e-2)" "unprognostic (3.60e-3)" "unprognostic (9.83e-3)" "unprognostic (2.43e-1)" "unprognostic (3.57e-2)" "unprognostic (1.13e-2)" 5.3 3.7 2.5 13.8 3.6 28.0 5.0 4.0 3.2 4.4 6.9 4.6 4.0 6.7 2.7 4.1 7.8 5.4 2.8 2.1 3.3 2.8 4.1 6.7 23.3 5.4 5.5 7.5 3.9 2.8 3.1 6.3 4.1 4.5 5.6 7.5 3.6 3.8 1.1 4.9 5.2 4.9 3.7 12.6 7.8 35.3 3.4 23.9 4.8 1.8 21.7 6.5 2.8 5.3 12.6 8.3 22.5 16.4 3.3 4.9 4.2 8.4 6.2 6.6 5.6 4.7 13.2 55.7 3.3 6.3 11.8 25.2 7.6 5.2 10.4 34.3 5.5 29.4 15.2 6.1 4.5 81.0 34.1 3.1 3.8 6.9 16.5 2.8 14.6 22.7 19.2 31.0 6.5 7.9 31.2 21.5 8.1 16.0 6.6 30.1 33.4 17.4 3.1 5.7 8.5 12.9 28.4 5.2 6.3 3.9 11.0 36.0 10.3 6.7 11.6 10.8 15.8 22.0 25.6 37.8 5.6 32.2 16.1 16.2 7.0 17.0 7.2 4.3 5.5 11.7 7.5 5.5 3.7 11.9 9.0 6.4 2.7 5.0 6.5 10.6 11.5 2.8 2.5 3.6 4.0 3.2 2.1 3.3 5.4 5.5 4.1 3.7 3.4 5.3 19.8 28.9 32.8 34.9 78.7 3.3 13.8 6.8 9.1 33.5 7.4 12.2 8.9 10.0 29.5 3.7 37.5 2.7 58.2 2.7 3.9 5.1 131.7 61.8 12.3 14.8 8.4 33.2 35.4 6.0 3.0 15.1 14.8 10.9 53.0 20.6 14.6 3.9 27.2 30.3 43.8 8.4 4.1 33.9 16.5 44.3 13.7 50.7 8.8 52.5 55.2 8.2 49.4 37.2 53.1 6.3 4.5 12.0 39.1 4.3 2.2 1.4 114.6 59.6 39.5 33.8 14.5 385.0 114.1 10.9 5.7 0.8 57.0 13.1 6.4 6.2 CREB5 "CRE-BPA, H_GS165L15.1" ENSG00000146592 "CAMP responsive element binding protein 5" Q02930 7 28299321-28825894 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.0" "Cell type enhanced" "Detected in many" "Adipocytes: 165.7;Basal prostatic cells: 192.2;monocytes: 163.9;Oligodendrocyte precursor cells: 229.7;Oligodendrocytes: 734.9" "Cancer enhanced" "Detected in many" "renal cancer: 5.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 198.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 198.8" "Cell line enhanced" "Detected in many" "HL-60: 62.5;Karpas-707: 25.0;U-2 OS: 25.7;U-2197: 28.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA050020, HPA061622" Approved "Nucleoplasm,Vesicles,Plasma membrane" NA Yes "Cluster 50: Neutrophils - Cellular senescence" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Vesicles, Plasma membrane" "HPA050020: AB_2680993, HPA061622: AB_2684569" "unprognostic (3.59e-2)" "unprognostic (3.80e-1)" "unprognostic (1.06e-1)" "unprognostic (6.46e-2)" "unprognostic (1.01e-1)" "unprognostic (4.90e-3)" "unprognostic (2.01e-3)" "unprognostic (2.87e-1)" "unprognostic (3.31e-1)" "unprognostic (1.04e-1)" "unprognostic (3.49e-1)" "unprognostic (2.67e-1)" "unprognostic (4.91e-3)" "unprognostic (6.61e-2)" "unprognostic (3.95e-1)" "unprognostic (1.60e-1)" "unprognostic (1.52e-3)" 10.5 1.3 6.3 7.9 20.5 6.1 5.0 6.8 12.7 1.7 0.0 3.5 0.9 8.4 2.8 3.5 2.2 11.4 5.3 9.6 19.9 3.0 1.8 6.1 0.9 19.7 14.6 0.7 3.2 0.2 1.1 3.7 15.8 1.2 1.7 1.3 3.5 1.0 3.2 2.9 2.2 4.7 2.9 7.4 1.4 0.7 23.0 0.7 1.8 4.0 0.8 4.4 2.2 35.0 0.1 0.6 7.3 0.4 0.4 10.3 0.3 0.7 1.6 4.4 6.6 4.2 2.7 18.9 1.3 1.8 4.5 0.7 0.2 6.4 13.8 0.0 5.0 20.4 4.2 0.4 0.4 62.5 0.7 1.3 1.2 18.9 20.1 0.9 3.0 0.1 2.4 25.0 1.5 0.1 0.1 0.0 9.1 0.1 7.4 0.5 6.8 0.5 9.0 2.0 0.7 5.2 0.3 0.4 2.2 10.0 0.2 1.5 0.8 8.6 25.7 28.7 8.5 1.5 4.5 0.2 9.4 0.3 14.8 0.1 29.9 0.0 0.0 9.7 0.0 1.9 0.0 0.0 18.2 0.1 0.0 0.0 198.8 0.0 3.9 0.3 0.0 7.0 6.3 20.5 6.8 12.7 9.6 19.9 19.7 14.6 15.8 2.9 23.0 35.0 165.7 6.4 7.2 10.7 3.2 21.9 192.2 8.2 13.1 1.3 10.7 8.9 16.8 17.2 6.3 12.9 0.0 4.0 0.8 0.0 1.9 74.2 0.4 41.0 56.3 31.3 0.0 0.4 17.0 27.4 13.4 108.0 3.1 69.7 14.0 0.6 14.3 0.5 8.3 5.0 22.2 0.0 6.1 47.4 118.2 1.6 5.9 75.8 30.2 22.5 163.9 14.3 4.1 229.7 734.9 22.5 0.0 0.4 3.2 44.9 0.0 25.6 4.7 0.9 19.7 143.5 31.8 12.6 7.3 12.0 13.2 24.8 3.1 2.6 0.0 35.1 CSKMT "CS-KMT, METTL12, U99HG" ENSG00000214756 "Citrate synthase lysine methyltransferase" A8MUP2 11 62665309-62668496 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Adipocytes: 40.4;Alveolar cells type 2: 41.4;Breast glandular cells: 65.9;Breast myoepithelial cells: 68.5;dendritic cells: 46.3;Endometrial stromal cells: 37.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in some" "Low region specificity" "Detected in all" HPA038533 Approved NA Yes "Cluster 30: Non-specific - Translation" "Cluster 6: T47d - Mammary gland" "Cluster 7: Non-specific - Mitochondria" "HPA038533: AB_10697392" "prognostic favorable (8.73e-4)" "unprognostic (2.59e-1)" "unprognostic (3.84e-1)" "unprognostic (1.15e-1)" "unprognostic (1.48e-2)" "unprognostic (3.17e-1)" "unprognostic (9.43e-5)" "unprognostic (1.55e-2)" "unprognostic (7.62e-2)" "unprognostic (2.88e-1)" "unprognostic (1.07e-1)" "unprognostic (2.54e-1)" "unprognostic (4.98e-3)" "unprognostic (2.72e-3)" "unprognostic (1.85e-1)" "unprognostic (1.57e-2)" "unprognostic (3.28e-1)" 0.3 0.3 0.4 0.1 0.3 0.1 0.4 0.3 0.7 0.5 0.3 0.4 0.5 0.4 0.1 0.5 0.5 0.1 0.3 0.3 0.4 0.3 0.3 0.2 0.2 0.4 0.3 0.6 0.7 0.1 0.2 0.5 0.4 0.4 0.4 0.1 0.3 0.4 0.9 0.3 0.2 0.1 0.3 0.2 0.4 0.0 0.4 0.2 0.2 0.2 0.3 0.4 0.5 0.4 0.9 0.9 0.3 0.4 2.6 1.0 0.4 0.3 0.6 0.7 0.9 0.7 0.9 1.6 0.4 1.2 0.2 1.7 1.6 0.8 1.4 0.5 0.0 0.6 0.0 1.0 0.0 0.0 0.6 0.9 2.7 0.2 1.0 0.7 0.2 0.2 0.7 0.0 1.0 0.8 0.5 0.7 1.6 0.0 0.8 0.8 0.4 0.2 0.3 0.1 0.0 0.0 0.8 1.0 0.9 0.4 2.0 0.2 0.0 0.2 0.9 2.4 0.0 0.3 0.0 0.0 0.2 0.4 0.4 0.7 1.1 0.1 0.8 1.8 1.7 2.9 2.4 1.1 1.1 1.5 2.9 2.5 0.0 0.5 1.3 1.3 1.3 1.4 0.4 0.3 0.3 0.7 0.3 0.4 0.4 0.3 0.4 0.3 0.4 0.4 40.4 12.8 41.4 0.0 25.0 0.0 0.0 0.0 0.0 0.0 65.9 68.5 0.0 0.0 21.1 18.4 0.0 27.7 46.3 0.0 5.9 7.4 0.0 17.5 37.7 10.1 0.0 0.0 0.0 5.6 20.0 13.2 0.0 23.0 27.8 15.3 0.0 0.0 19.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 0.0 0.0 2.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 8.8 0.0 0.0 9.8 6.6 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.0 26.5 24.4 13.5 0.0 0.0 DCLRE1B "APOLLO, FLJ12810, FLJ13998, SNM1B" ENSG00000118655 "DNA cross-link repair 1B" Q9H816 1 113905213-113914086 "Disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 23.6;Sertoli cells: 26.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 57.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064934 Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Nuclear bodies" "HPA064934: AB_2685387" "unprognostic (1.21e-1)" "unprognostic (3.38e-2)" "unprognostic (4.47e-3)" "unprognostic (4.92e-3)" "unprognostic (1.89e-1)" "unprognostic (1.02e-2)" "prognostic unfavorable (4.50e-5)" "unprognostic (1.31e-2)" "unprognostic (9.67e-3)" "unprognostic (2.73e-2)" "prognostic unfavorable (6.70e-4)" "unprognostic (1.15e-1)" "prognostic unfavorable (5.03e-7)" "unprognostic (1.24e-2)" "unprognostic (2.13e-1)" "unprognostic (1.25e-1)" "unprognostic (5.08e-2)" 3.5 1.2 2.5 3.7 2.7 6.0 2.9 4.5 2.8 2.5 2.1 2.8 1.7 2.4 1.6 3.0 2.7 2.2 1.3 2.4 2.7 1.6 1.7 3.2 4.1 2.5 2.7 3.0 0.9 1.1 0.7 3.5 2.5 1.7 3.0 1.2 1.2 1.9 0.8 2.6 1.9 3.3 2.5 4.0 1.6 2.4 2.8 4.8 2.0 1.0 3.9 2.2 1.6 3.3 14.1 5.5 9.9 10.5 7.9 5.4 5.7 11.1 7.4 14.2 15.3 6.0 3.9 14.3 6.8 7.8 6.4 6.4 13.7 11.2 19.6 12.0 10.1 12.4 7.8 5.9 1.5 14.1 12.1 6.2 4.4 18.5 10.6 3.9 7.9 16.5 17.5 11.8 16.7 57.8 21.7 11.5 7.7 5.5 12.6 17.2 30.4 6.5 5.6 6.1 8.7 8.0 12.0 9.2 7.7 7.8 6.1 14.9 4.8 18.6 19.6 31.3 15.8 5.2 5.6 16.0 15.7 13.8 32.9 1.9 4.5 1.3 2.3 3.7 2.5 0.9 2.6 2.2 2.6 1.4 1.7 2.2 0.2 5.8 2.1 1.0 1.8 2.5 2.5 2.7 4.5 2.8 2.4 2.7 2.5 2.7 2.5 2.5 2.8 3.3 3.0 3.2 2.0 0.3 2.8 3.6 1.2 1.7 8.0 3.0 2.6 2.0 1.2 1.5 0.8 0.0 2.1 4.6 4.0 1.0 1.9 4.4 1.3 4.1 2.3 3.4 3.0 23.6 0.8 2.7 9.8 3.4 0.5 2.4 1.3 5.6 2.2 1.6 9.7 1.7 0.9 3.1 2.0 8.5 12.8 0.6 1.8 10.5 0.0 1.0 13.5 0.9 2.1 0.0 1.1 3.7 0.5 2.2 5.0 1.5 0.3 1.7 3.1 1.4 26.3 2.1 5.5 7.9 11.4 6.2 2.7 1.4 4.4 3.0 4.2 1.0 DCTPP1 "CDA03, MGC5627, RS21C6, XTP3TPA" ENSG00000179958 "DCTP pyrophosphatase 1" Q9H773 16 30423615-30430030 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002832 Uncertain Supported Nucleoplasm,Cytosol NA Yes 61000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "HPA002832: AB_1080615" "prognostic unfavorable (1.64e-5)" "unprognostic (1.61e-1)" "unprognostic (1.99e-3)" "unprognostic (1.17e-2)" "unprognostic (1.36e-1)" "unprognostic (4.09e-2)" "prognostic unfavorable (6.28e-4)" "unprognostic (2.23e-1)" "unprognostic (1.07e-1)" "unprognostic (4.35e-2)" "unprognostic (2.43e-2)" "unprognostic (3.65e-2)" "prognostic favorable (9.71e-9)" "unprognostic (1.10e-3)" "unprognostic (8.78e-3)" "unprognostic (1.10e-2)" "unprognostic (2.53e-1)" 21.0 21.4 17.6 27.4 18.4 22.2 30.5 18.7 22.5 18.6 18.9 56.4 32.0 18.6 20.0 28.3 28.1 19.5 31.1 18.4 19.5 39.7 21.8 16.2 35.5 18.1 17.6 14.0 24.9 32.1 10.3 16.0 19.0 21.8 58.4 12.2 25.5 19.3 44.7 25.1 27.7 20.5 18.4 27.8 24.3 9.1 18.1 24.5 20.1 36.9 35.7 27.0 19.1 19.4 124.7 149.8 66.8 85.8 18.4 24.1 61.9 58.4 35.1 87.4 87.9 114.7 103.4 168.1 119.1 36.8 54.9 95.9 141.4 115.1 103.5 89.2 221.0 98.3 61.5 150.3 24.1 177.0 144.2 28.6 64.8 96.4 55.6 25.4 88.7 88.2 125.8 57.4 61.5 217.8 210.0 189.9 88.8 124.2 119.2 293.1 74.8 218.1 98.9 80.2 141.4 80.4 39.0 137.7 55.3 41.5 118.4 73.9 45.9 66.0 59.1 85.8 107.2 36.9 118.4 217.5 43.8 145.7 79.6 70.6 36.7 38.1 54.0 70.0 75.8 146.7 68.4 61.4 86.7 128.7 60.9 59.0 4.6 76.1 79.2 94.6 76.4 81.0 17.6 18.4 18.7 22.5 18.4 19.5 18.1 17.6 19.0 18.4 18.1 19.4 34.0 19.2 15.2 0.7 38.2 90.2 53.3 92.5 33.6 23.3 45.8 48.9 34.8 51.5 37.9 44.1 8.4 103.2 22.7 130.3 127.2 135.6 13.4 32.6 29.9 47.4 38.5 29.6 2.6 124.8 101.0 28.3 27.5 66.5 31.1 40.2 31.1 23.2 76.9 15.2 2.7 142.3 73.2 21.0 49.1 45.1 19.6 26.9 48.0 1.0 73.2 25.0 23.7 2.5 4.4 89.0 115.8 19.9 24.1 86.9 68.8 76.7 27.8 21.4 19.7 23.7 40.0 3.3 44.8 39.4 80.3 27.8 28.3 53.8 168.5 45.7 DDX11 "CHL1, CHLR1, KRG2, WABS" ENSG00000013573 "DEAD/H-box helicase 11" Q96FC9 12 31073860-31104799 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Host-virus interaction, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Helicase, Hydrolase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 25.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA065197 Supported Supported Nucleoplasm,Nucleoli No Yes "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 5: NTERA-2 - Transcription" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "HPA065197: AB_2685430" "unprognostic (6.10e-2)" "unprognostic (1.48e-2)" "unprognostic (1.02e-1)" "unprognostic (5.09e-2)" "unprognostic (1.45e-1)" "unprognostic (2.79e-3)" "prognostic unfavorable (2.40e-4)" "unprognostic (4.87e-2)" "unprognostic (3.89e-3)" "unprognostic (3.53e-1)" "unprognostic (5.66e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (5.23e-8)" "unprognostic (1.89e-2)" "unprognostic (3.64e-2)" "unprognostic (1.02e-1)" "unprognostic (8.03e-3)" 5.9 6.4 6.0 10.2 6.8 29.2 7.2 6.9 7.3 10.7 7.1 9.6 8.0 7.5 4.3 9.5 8.0 5.9 5.3 6.0 6.1 9.2 9.3 6.1 13.2 6.9 6.4 11.0 17.5 5.8 9.4 5.4 6.9 10.0 10.1 6.6 8.6 5.3 10.6 16.7 13.4 3.6 6.1 13.8 9.6 8.8 6.7 24.0 8.0 6.6 11.1 6.9 9.8 6.9 36.5 35.0 42.2 34.5 5.8 11.0 58.7 21.8 10.4 25.2 28.5 44.1 58.6 49.2 23.9 10.8 23.6 35.0 31.7 28.9 21.3 43.4 66.6 47.4 71.0 25.4 2.1 37.4 35.0 11.9 13.0 32.6 24.8 16.9 12.6 55.2 26.6 103.3 17.6 30.9 64.5 60.7 84.0 39.9 19.5 55.0 53.3 66.2 13.3 38.5 30.2 21.7 23.4 33.2 10.4 65.0 27.3 25.5 8.2 22.0 42.1 42.2 40.0 39.4 29.6 95.3 24.6 32.5 20.3 0.0 1.3 0.8 2.0 1.2 1.5 2.5 1.9 1.5 1.5 2.6 2.0 2.6 0.5 2.2 4.4 2.4 2.0 1.3 6.0 6.8 6.9 7.3 6.0 6.1 6.9 6.4 6.9 6.1 6.7 6.9 10.1 3.2 9.5 1.6 9.0 6.0 4.0 6.0 2.2 9.4 8.3 7.1 2.5 4.3 6.0 0.0 14.6 7.6 8.8 7.8 0.0 2.0 1.7 5.5 8.9 5.4 0.0 15.3 2.5 3.3 7.5 5.7 9.7 7.4 5.7 15.6 6.1 7.7 5.2 8.4 3.6 6.5 10.2 4.1 5.4 1.3 7.2 4.4 7.2 3.7 3.5 2.7 4.1 1.5 1.7 3.2 2.7 4.5 17.2 6.0 2.3 1.4 6.7 25.8 0.0 4.9 4.8 5.3 18.0 5.5 6.5 2.6 8.4 4.1 9.5 5.1 DLGAP5 "DLG1, DLG7, HURP, KIAA0008" ENSG00000126787 "DLG associated protein 5" Q15398 14 55148112-55191608 "Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 29.7;lymphoid tissue: 42.0;testis: 17.4" "Cell type enhanced" "Detected in many" "Erythroid cells: 92.6;Extravillous trophoblasts: 23.1;Plasma cells: 22.1;Spermatocytes: 68.1;Spermatogonia: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 5.4" "Lineage enriched" "Detected in many" 5 "T-cells: 5.4" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA005546 Enhanced Supported "Centriolar satellite,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Centriolar satellite, Cytosol" "HPA005546: AB_1078677" "unprognostic (2.24e-1)" "unprognostic (1.77e-1)" "unprognostic (1.19e-3)" "prognostic unfavorable (4.59e-4)" "unprognostic (1.42e-1)" "unprognostic (1.66e-2)" "prognostic unfavorable (1.52e-6)" "prognostic unfavorable (7.85e-4)" "unprognostic (6.15e-3)" "unprognostic (3.55e-1)" "prognostic unfavorable (9.94e-6)" "unprognostic (4.69e-2)" "unprognostic (0.00e+0)" "unprognostic (1.06e-2)" "unprognostic (3.64e-1)" "unprognostic (1.29e-1)" "unprognostic (1.93e-2)" 0.8 0.3 1.4 8.1 0.9 29.7 1.4 0.4 1.8 0.8 0.6 5.5 5.0 1.3 0.1 5.2 0.4 0.8 0.2 1.0 1.7 0.2 0.7 0.7 17.9 0.7 1.0 0.2 0.1 0.2 0.0 4.1 0.8 0.2 6.7 0.1 0.8 0.1 0.1 3.1 4.6 2.7 0.3 2.6 3.0 17.4 1.1 42.0 0.4 0.0 18.7 2.0 1.5 3.8 144.8 56.8 140.6 63.7 3.3 13.4 43.8 80.3 52.7 115.3 109.3 45.9 75.8 82.1 44.2 46.9 47.4 85.6 91.5 64.0 150.5 101.9 45.7 84.4 49.9 39.3 0.4 82.7 49.3 2.8 2.2 54.8 27.0 18.9 129.0 82.5 70.5 79.8 109.3 69.2 105.0 42.7 72.6 63.3 57.3 80.8 137.9 39.0 37.9 45.2 71.7 40.7 84.8 31.7 30.8 60.6 71.6 31.6 49.6 52.4 133.3 50.6 94.6 19.4 44.9 108.9 35.9 59.6 83.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.9 1.4 0.3 0.0 0.2 0.1 0.2 1.0 0.0 0.0 5.4 0.7 1.4 0.9 0.4 1.8 1.0 1.7 0.7 1.0 0.8 0.3 1.1 3.8 0.1 0.0 0.5 0.0 4.4 1.1 0.7 3.3 0.0 0.0 1.2 0.9 0.4 0.0 1.3 0.0 0.0 11.6 1.4 3.2 0.0 0.4 19.7 7.2 2.6 2.4 0.0 92.6 0.3 0.0 23.1 4.2 7.7 4.5 0.0 15.8 3.9 0.5 10.5 0.0 0.3 3.6 8.2 4.1 1.6 6.0 0.9 3.7 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.2 0.2 1.2 22.1 0.6 0.3 0.1 1.3 0.0 6.6 0.0 3.8 68.1 31.7 11.6 0.4 1.9 4.0 0.9 6.9 1.4 DNA2 "DNA2L, KIAA0083" ENSG00000138346 "DNA replication helicase/nuclease 2" P51530 10 68414064-68472121 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, Endonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease" "Disease variant, Dwarfism, Mental retardation, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 33.2;Excitatory neurons: 14.1;Inhibitory neurons: 15.5;Oligodendrocytes: 18.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "NK-cell: 1.8" "Lineage enriched" "Detected in single" 5 "NK-cells: 1.8" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA037487, HPA057526" Approved Supported Mitochondria No Yes "Cluster 15: NK-cells - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "HPA037487: AB_10672493, HPA057526: AB_2683456" "unprognostic (1.79e-1)" "unprognostic (1.35e-1)" "unprognostic (4.37e-3)" "unprognostic (4.60e-3)" "unprognostic (1.53e-1)" "unprognostic (1.86e-2)" "unprognostic (4.50e-5)" "unprognostic (3.36e-2)" "unprognostic (4.70e-2)" "unprognostic (3.72e-2)" "unprognostic (1.30e-2)" "unprognostic (3.29e-4)" "unprognostic (1.09e-10)" "unprognostic (3.43e-2)" "unprognostic (1.98e-1)" "unprognostic (9.36e-2)" "unprognostic (1.23e-2)" 1.3 0.9 1.9 2.8 2.1 4.6 1.8 2.5 3.6 1.4 1.0 2.3 2.1 1.1 0.9 1.9 0.9 0.9 1.8 1.8 1.9 2.6 4.2 1.8 5.2 2.3 1.9 1.2 1.6 0.4 1.5 1.6 2.4 1.9 2.8 5.3 1.6 0.4 1.6 1.8 3.2 1.1 1.6 2.1 1.9 2.9 2.1 8.1 1.0 0.9 4.2 1.4 1.4 3.2 25.6 13.0 29.0 20.7 3.2 2.2 20.4 12.4 10.3 17.4 21.2 31.1 16.1 26.1 4.6 3.8 6.7 15.2 16.8 6.5 20.7 16.2 12.6 15.8 8.5 12.3 0.9 27.7 16.4 1.8 2.6 12.3 3.6 4.5 7.9 17.0 23.6 22.8 10.1 9.0 42.8 19.8 20.5 10.9 24.0 33.1 20.0 8.4 7.5 11.7 13.1 15.7 16.9 21.4 4.2 20.1 16.5 11.6 3.4 6.6 20.5 8.5 23.8 11.5 13.9 38.3 5.7 26.1 8.9 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.1 0.1 0.0 1.8 0.0 0.0 0.1 0.0 1.9 2.1 2.5 3.6 1.8 1.9 2.3 1.9 2.4 1.6 2.1 3.2 1.0 6.4 1.1 4.9 1.3 2.3 0.9 1.7 2.8 2.5 2.3 1.4 10.5 2.8 1.1 1.8 6.2 3.9 2.2 1.7 0.0 0.8 2.2 2.0 1.4 2.0 1.2 33.2 14.1 0.9 4.8 2.0 2.6 2.8 0.0 6.0 0.7 4.6 2.2 0.0 15.5 1.8 0.0 1.3 0.7 3.7 0.6 1.5 0.0 4.7 0.5 0.5 2.1 5.5 18.4 0.7 0.1 0.7 7.4 2.5 2.4 0.6 0.8 4.3 0.0 2.4 1.1 9.1 12.2 4.7 1.7 1.2 1.6 0.7 3.7 1.0 DNAJA1 "dj-2, hdj-2, HSJ2, HSPF4, NEDD7" ENSG00000086061 "DnaJ heat shock protein family (Hsp40) member A1" P31689 9 33025273-33039907 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 438.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001306, CAB033665" Approved Supported Microtubules,Cytosol NA Yes 160000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 65: Brain - Ion transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Cytosol Microtubules "CAB033665: AB_2094242, HPA001306: AB_1079043" "unprognostic (3.11e-2)" "unprognostic (5.05e-2)" "unprognostic (5.14e-2)" "unprognostic (1.16e-1)" "unprognostic (1.07e-1)" "unprognostic (9.80e-2)" "unprognostic (3.17e-2)" "unprognostic (2.88e-2)" "unprognostic (5.58e-2)" "prognostic favorable (5.39e-4)" "unprognostic (1.69e-2)" "unprognostic (1.05e-1)" "prognostic favorable (3.40e-4)" "unprognostic (3.27e-1)" "unprognostic (2.65e-1)" "unprognostic (1.25e-1)" "unprognostic (4.70e-2)" 102.6 134.7 143.9 83.9 154.7 148.8 65.8 147.4 438.9 83.7 142.7 61.9 44.5 81.0 80.4 51.7 102.7 83.6 72.9 154.1 159.8 114.6 216.9 94.4 80.6 147.7 152.8 83.5 59.7 105.2 80.7 108.3 160.9 85.8 63.5 78.2 61.0 64.7 47.3 43.8 50.1 87.2 155.3 72.0 67.7 135.0 164.6 95.7 66.0 61.5 89.1 130.7 57.3 174.0 255.6 447.5 353.7 123.6 240.2 155.1 202.4 256.5 205.9 451.2 348.2 299.2 115.0 259.5 191.6 175.4 254.9 113.1 515.7 154.7 386.1 368.2 150.2 208.3 537.3 382.7 115.1 242.5 234.2 96.1 156.1 170.4 53.9 218.4 273.6 110.9 330.5 109.7 262.0 208.6 407.7 530.3 345.3 254.2 308.2 294.7 126.6 132.9 254.1 148.8 223.8 243.5 345.4 220.6 120.0 262.5 103.5 231.5 236.1 160.0 273.1 184.6 346.2 69.9 233.3 271.7 209.9 208.3 140.9 154.1 140.8 160.9 93.3 202.0 111.1 127.5 116.8 105.7 127.8 119.7 119.6 113.4 176.2 117.8 268.3 213.4 110.4 209.9 143.9 154.7 147.4 438.9 154.1 159.8 147.7 152.8 160.9 155.3 164.6 174.0 1110.8 214.7 154.9 7.8 368.7 264.6 942.8 245.3 327.8 209.3 307.8 513.5 187.7 95.8 257.7 82.8 208.5 274.0 619.1 287.9 172.1 247.7 536.4 549.2 348.2 427.8 391.1 198.9 16.2 181.1 341.6 392.8 188.6 526.1 424.7 127.6 133.2 129.6 231.1 121.1 16.7 327.3 213.6 156.0 497.4 222.2 99.1 402.3 284.6 22.5 243.7 150.5 91.6 8.0 22.5 189.8 334.7 94.8 195.8 393.8 134.7 178.1 417.8 161.7 105.2 391.1 476.0 492.7 209.4 238.5 265.4 464.9 678.9 179.2 273.3 636.8 DNAJC2 "MPHOSPH11, MPP11, ZRF1, ZUO1, zuotin" ENSG00000105821 "DnaJ heat shock protein family (Hsp40) member C2" Q99543 7 103312289-103344830 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chaperone, Chromatin regulator" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 248.5;Spermatocytes: 238.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 61.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020454 Approved Supported Cytosol NA Yes "Cluster 42: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA020454: AB_1859492" "unprognostic (1.07e-1)" "unprognostic (1.66e-1)" "unprognostic (5.53e-2)" "unprognostic (2.20e-2)" "unprognostic (1.11e-1)" "unprognostic (7.71e-2)" "unprognostic (2.13e-3)" "unprognostic (2.13e-3)" "unprognostic (1.63e-2)" "unprognostic (5.35e-2)" "unprognostic (2.21e-2)" "unprognostic (1.27e-2)" "prognostic unfavorable (1.12e-5)" "unprognostic (1.11e-1)" "unprognostic (2.30e-1)" "unprognostic (3.51e-1)" "unprognostic (3.28e-1)" 15.7 13.4 10.2 12.2 10.7 42.0 13.4 12.7 19.2 13.1 10.5 11.9 14.7 12.8 9.7 13.8 12.1 9.8 13.5 10.5 10.4 16.4 15.7 11.2 16.8 10.0 10.7 15.7 13.4 9.0 12.6 11.9 10.3 12.3 11.9 8.7 12.6 7.7 32.5 13.6 11.9 7.4 9.3 12.2 12.9 31.3 11.4 12.3 12.7 12.7 13.2 18.8 12.8 11.8 52.7 38.1 21.4 38.7 16.1 22.6 41.6 35.1 25.8 38.5 28.6 52.9 37.2 74.9 53.7 24.4 55.2 35.5 57.5 25.7 58.4 40.6 43.4 55.1 38.7 47.3 28.6 97.9 41.2 19.6 21.9 44.9 39.4 16.2 25.6 27.8 128.3 46.2 32.0 83.8 95.0 102.1 75.9 56.8 57.0 59.7 43.0 70.1 22.8 24.8 40.6 38.7 47.7 66.2 39.7 39.6 28.1 49.8 30.8 37.5 59.9 83.3 68.1 48.9 67.8 146.0 27.3 97.9 47.6 61.3 9.0 9.3 10.9 10.3 12.1 11.7 10.9 11.7 9.4 13.7 12.5 12.5 3.6 16.4 15.3 11.2 12.8 5.9 10.2 10.7 12.7 19.2 10.5 10.4 10.0 10.7 10.3 9.3 11.4 11.8 31.3 25.6 47.0 10.7 46.1 64.6 78.7 37.3 35.3 27.1 26.3 36.6 32.3 22.8 50.2 22.0 41.7 43.7 45.9 31.1 35.2 45.0 248.5 43.8 50.1 39.6 35.3 29.9 24.7 46.0 75.5 41.0 42.8 44.2 53.7 50.1 18.5 30.6 39.6 21.9 17.9 39.0 26.4 24.5 41.3 37.3 39.4 37.8 19.6 13.1 42.9 19.3 44.3 24.1 20.6 50.2 32.9 31.2 36.9 79.2 36.4 31.0 43.4 29.0 39.5 63.7 64.8 238.7 131.9 33.5 62.1 55.4 43.2 58.3 51.9 91.5 DTL "CDT2, DCAF2, L2DTL, RAMP" ENSG00000143476 "Denticleless E3 ubiquitin protein ligase homolog" Q9NZJ0 1 212035553-212107400 "Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA replication, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 14.6;intestine: 4.7;lymphoid tissue: 14.2;placenta: 3.9;testis: 13.7" "Cell type enhanced" "Detected in many" "Early spermatids: 25.3;Erythroid cells: 36.2;Extravillous trophoblasts: 16.2;Spermatocytes: 53.2;Spermatogonia: 20.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 2.0" "Lineage enriched" "Detected in single" 8 "T-cells: 2.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028016, HPA032023, HPA032031" Supported Supported Nucleoplasm,Nucleoli,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli, Cytosol" "HPA028016: AB_10611958, HPA032023: AB_2674114, HPA032031: AB_2674119" "unprognostic (7.61e-2)" "unprognostic (1.01e-3)" "unprognostic (2.14e-2)" "unprognostic (3.05e-2)" "unprognostic (2.19e-1)" "unprognostic (5.31e-2)" "prognostic unfavorable (4.41e-5)" "unprognostic (8.96e-3)" "unprognostic (2.45e-3)" "unprognostic (8.83e-3)" "unprognostic (2.52e-3)" "unprognostic (2.83e-2)" "prognostic unfavorable (1.71e-9)" "unprognostic (5.93e-2)" "unprognostic (2.01e-1)" "unprognostic (1.96e-2)" "unprognostic (2.82e-1)" 0.6 0.2 0.0 4.1 0.0 14.6 1.9 0.0 0.1 0.6 0.0 3.3 2.3 1.1 0.1 1.9 0.4 0.4 0.1 0.0 0.0 0.1 1.2 1.4 5.6 0.0 0.1 0.1 0.1 0.5 0.2 3.9 0.0 0.4 4.7 0.0 0.4 0.1 0.1 2.1 3.0 1.9 0.0 2.5 1.3 13.7 0.1 14.2 0.5 0.0 6.4 1.2 0.7 0.0 34.1 28.1 48.0 23.6 2.9 5.8 23.3 41.3 25.5 38.1 56.1 17.6 29.0 25.2 15.4 16.1 25.0 25.8 62.5 34.9 54.7 31.4 30.9 40.7 33.6 21.5 0.1 54.1 25.3 2.5 1.2 62.2 32.4 6.8 17.7 44.7 49.1 51.1 44.4 13.5 75.3 24.3 56.6 25.2 32.9 57.2 84.0 49.2 11.6 22.9 29.6 46.0 39.2 37.5 17.6 47.7 32.0 24.1 9.7 38.2 28.6 40.5 47.8 18.4 30.5 57.7 19.1 35.5 37.8 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.3 0.5 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 2.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 2.3 2.3 0.4 1.7 0.0 0.0 1.3 1.3 7.0 1.5 0.9 0.0 0.0 12.8 1.4 1.5 0.0 0.4 25.3 0.4 1.3 5.2 0.0 36.2 0.2 0.0 16.2 2.4 3.1 1.0 0.0 11.4 0.7 0.4 4.7 0.0 0.3 3.3 0.0 0.3 0.8 12.4 1.2 2.2 0.0 1.0 0.2 0.0 0.0 0.0 0.1 0.6 0.4 0.0 12.8 0.2 0.6 0.0 0.1 0.0 0.0 0.2 2.7 53.2 20.8 5.6 1.7 1.5 2.6 1.6 5.2 0.7 DUT dUTPase ENSG00000128951 "Deoxyuridine triphosphatase" P33316 15 48331011-48343373 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 508.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054422, HPA060360" Enhanced Supported Nucleoplasm No Yes 31000 "Cluster 26: Non-specific - Mitochondria" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA054422: AB_2682483, HPA060360: AB_2684262" "unprognostic (1.82e-1)" "unprognostic (3.49e-2)" "unprognostic (7.89e-2)" "unprognostic (5.27e-2)" "unprognostic (2.20e-1)" "unprognostic (7.17e-2)" "unprognostic (1.65e-1)" "unprognostic (1.16e-2)" "unprognostic (4.42e-3)" "unprognostic (1.87e-2)" "unprognostic (4.25e-1)" "unprognostic (3.54e-2)" "unprognostic (3.68e-2)" "unprognostic (4.23e-2)" "unprognostic (1.47e-1)" "unprognostic (2.09e-2)" "unprognostic (1.71e-2)" 73.0 65.3 54.7 61.7 58.9 162.9 76.4 57.1 77.2 90.7 60.0 69.5 29.3 76.9 49.7 72.1 77.6 33.6 68.9 53.9 59.6 67.6 53.6 58.1 97.8 58.2 55.5 86.1 53.2 48.3 80.0 45.1 58.3 77.8 47.1 49.1 66.5 48.3 57.9 71.6 66.5 40.4 57.7 82.1 61.5 57.3 57.5 111.4 89.2 53.0 87.8 69.1 78.0 63.5 196.1 60.2 143.9 137.1 98.4 104.0 85.3 202.1 128.1 182.8 224.6 69.8 131.0 539.3 106.0 112.0 149.4 262.1 152.4 138.4 177.6 383.4 157.2 442.2 151.8 96.1 54.8 469.0 202.0 64.4 92.1 123.9 65.0 117.8 123.3 316.6 244.0 297.6 136.5 79.3 422.4 548.7 90.7 197.4 114.5 338.6 313.9 570.0 120.8 130.4 207.2 210.1 150.0 119.6 184.4 145.5 169.6 368.6 103.0 190.1 183.1 228.3 269.7 238.1 534.3 532.5 143.6 789.4 213.4 32.5 50.3 46.8 52.9 53.1 68.7 94.8 94.7 84.6 74.0 90.0 97.4 64.3 30.9 60.5 68.4 85.3 94.3 71.4 54.7 58.9 57.1 77.2 53.9 59.6 58.2 55.5 58.3 57.7 57.5 63.5 153.6 54.5 38.9 39.8 126.8 179.6 212.0 222.4 131.5 48.3 158.0 205.5 120.1 95.8 118.5 104.8 14.6 221.8 103.9 62.8 203.5 94.3 36.8 67.2 123.5 123.0 96.1 418.8 36.5 46.5 286.8 147.9 76.5 86.0 84.4 118.3 101.4 77.6 174.5 82.4 32.1 98.4 105.8 87.7 112.6 31.5 184.8 92.0 154.7 23.4 89.5 106.3 95.8 23.6 45.1 45.4 58.8 177.6 192.3 133.2 27.2 256.4 59.6 40.9 157.8 167.1 154.0 508.7 270.0 206.4 168.5 97.1 124.4 82.3 195.4 181.2 DYNLL1 "DLC1, DLC8, DNCL1, hdlc1, LC8, PIN" ENSG00000088986 "Dynein light chain LC8-type 1" P63167 12 120469850-120498493 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Transcription, Transcription regulation, Transport" "Activator, Motor protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 4098.6;Respiratory ciliated cells: 2679.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039954 Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA Yes 890000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 27: Brain & Skin - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA039954: AB_2676771" "unprognostic (1.94e-1)" "unprognostic (1.08e-1)" "unprognostic (3.43e-2)" "unprognostic (2.88e-2)" "unprognostic (5.63e-2)" "unprognostic (7.09e-2)" "prognostic unfavorable (7.33e-5)" "unprognostic (4.41e-3)" "unprognostic (4.64e-2)" "unprognostic (6.17e-3)" "unprognostic (1.61e-2)" "unprognostic (9.10e-2)" "prognostic unfavorable (7.97e-7)" "unprognostic (4.91e-2)" "unprognostic (2.80e-2)" "unprognostic (7.91e-2)" "unprognostic (1.62e-1)" 268.6 261.9 912.5 186.7 967.7 126.8 268.0 895.2 1292.9 354.2 894.7 325.8 162.8 319.4 322.3 719.9 544.2 242.7 257.5 975.4 944.7 352.6 238.4 222.6 241.6 896.1 898.5 247.0 225.1 228.2 309.7 259.2 914.2 225.9 327.4 181.3 245.4 264.6 85.6 626.7 206.3 390.1 935.1 185.2 244.5 360.3 909.7 306.5 176.1 163.9 357.8 389.8 474.4 1001.2 721.6 811.4 779.2 600.8 677.1 713.6 250.8 968.0 451.6 785.6 466.7 770.8 472.3 400.6 510.3 945.1 753.0 629.6 949.3 818.3 781.0 528.3 617.9 390.4 532.9 1062.5 676.2 412.8 620.5 436.2 863.0 584.6 477.5 855.7 831.8 421.5 502.0 446.1 1056.8 960.1 541.4 894.8 642.2 917.7 935.7 543.0 403.0 499.2 1143.1 659.8 535.2 392.0 789.3 677.7 926.6 812.6 673.6 595.3 635.2 592.3 502.1 525.6 852.2 264.0 562.8 404.6 656.8 645.1 776.6 516.6 291.9 384.2 200.6 303.3 155.3 310.4 207.2 211.7 281.8 219.0 132.0 165.7 50.1 282.9 334.8 461.6 373.5 353.0 912.5 967.7 895.2 1292.9 975.4 944.7 896.1 898.5 914.2 935.1 909.7 1001.2 810.1 195.5 101.9 79.3 341.4 922.2 359.1 1275.0 356.8 138.4 800.0 949.4 170.8 303.1 764.6 399.1 83.4 524.6 484.1 689.9 1113.2 691.2 1407.2 1842.5 528.5 541.9 480.8 332.9 111.2 538.9 897.4 538.5 240.5 488.1 316.7 611.9 521.9 499.0 732.1 85.8 62.8 801.6 1121.0 329.4 706.1 4098.6 516.6 466.3 595.9 42.2 701.6 164.0 248.2 47.3 156.4 754.9 798.6 701.8 234.9 304.7 533.4 1125.0 2679.6 193.5 368.1 440.7 1016.3 961.5 721.4 1005.4 1610.1 1006.6 396.6 586.3 498.2 389.6 E2F1 "RBBP3, RBP3" ENSG00000101412 "E2F transcription factor 1" Q01094 20 33675477-33686385 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 25.0;Granulosa cells: 11.4;Spermatogonia: 32.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000329, HPA008003, CAB019308, HPA029735" Enhanced Supported Nucleoplasm,Centrosome NA Yes "Cluster 22: NK-cells - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Centrosome" "CAB000329: AB_627476, CAB019308: , HPA008003: AB_1847936, HPA029735: AB_2673176" "unprognostic (7.46e-2)" "prognostic favorable (9.22e-6)" "unprognostic (2.11e-2)" "prognostic unfavorable (4.33e-5)" "unprognostic (1.51e-1)" "unprognostic (1.21e-2)" "prognostic unfavorable (3.83e-5)" "unprognostic (1.25e-2)" "unprognostic (8.23e-2)" "unprognostic (9.66e-2)" "prognostic unfavorable (4.18e-4)" "unprognostic (3.15e-2)" "prognostic unfavorable (8.99e-5)" "unprognostic (1.05e-2)" "unprognostic (7.50e-2)" "prognostic favorable (1.62e-4)" "unprognostic (1.91e-1)" 1.8 5.5 7.1 5.6 7.1 34.3 1.6 5.2 9.2 1.8 3.9 3.8 3.2 1.2 0.2 5.7 1.3 0.7 1.4 6.1 5.6 0.9 1.8 3.7 8.7 7.6 6.4 3.5 1.0 1.3 0.6 2.4 6.5 1.9 3.9 0.7 1.9 0.9 1.6 4.7 4.1 2.8 7.0 5.0 3.7 10.4 6.9 10.7 0.8 0.8 6.9 2.4 2.5 8.3 48.1 45.4 52.0 40.5 5.2 3.6 39.3 45.0 21.4 55.9 46.7 81.1 48.0 87.3 44.2 20.2 67.7 35.4 25.3 23.8 24.8 26.4 36.5 71.6 71.9 47.7 0.4 34.0 43.6 2.8 1.4 30.6 5.4 5.7 14.6 54.4 19.3 60.0 34.9 42.3 72.8 71.6 15.6 47.9 64.6 71.4 140.7 36.2 9.6 28.7 76.7 54.1 54.6 37.6 22.7 14.8 47.3 42.4 7.9 65.0 37.7 45.8 64.8 58.1 42.0 72.6 54.1 20.0 39.3 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.4 1.0 0.1 0.1 0.1 7.1 7.1 5.2 9.2 6.1 5.6 7.6 6.4 6.5 7.0 6.9 8.3 1.1 0.0 1.1 0.7 3.6 2.9 1.7 0.5 0.0 2.3 3.1 4.3 0.4 0.0 1.4 0.0 0.0 5.0 2.9 2.4 0.0 0.9 1.0 0.3 1.0 1.6 0.0 25.0 1.5 0.2 9.6 3.0 7.7 1.2 0.0 11.4 0.7 0.8 4.4 0.0 0.5 4.6 2.0 0.6 2.1 3.1 2.1 3.1 1.8 1.0 0.1 1.5 1.0 1.0 3.4 0.6 0.5 1.2 9.7 0.5 1.4 0.1 0.2 2.3 0.0 1.0 3.0 7.5 32.9 3.7 1.7 1.8 3.3 1.2 7.0 3.5 E2F2 E2F-2 ENSG00000007968 "E2F transcription factor 2" Q14209 1 23506438-23531233 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 25.1;esophagus: 8.7;lymphoid tissue: 15.8" "Group enriched" "Detected in many" 4 "Early spermatids: 50.2;Erythroid cells: 45.7;Late spermatids: 110.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 4.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 46.7;Karpas-707: 38.9;U-266/84: 37.2;U-698: 38.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" CAB016313 Uncertain NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" "CAB016313: AB_2096794" "unprognostic (3.14e-2)" "unprognostic (5.74e-3)" "unprognostic (1.31e-3)" "unprognostic (4.18e-2)" "unprognostic (8.54e-2)" "unprognostic (1.70e-3)" "unprognostic (6.43e-6)" "unprognostic (7.83e-3)" "unprognostic (1.53e-2)" "unprognostic (7.33e-2)" "unprognostic (1.51e-3)" "unprognostic (1.86e-2)" "unprognostic (0.00e+0)" "unprognostic (1.00e-3)" "unprognostic (2.82e-1)" "unprognostic (8.67e-3)" "unprognostic (1.84e-1)" 0.2 0.2 0.0 1.8 0.0 25.1 0.1 0.1 0.1 0.9 0.1 3.4 1.5 0.1 0.0 8.7 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.8 3.2 0.0 0.1 0.0 0.1 0.0 0.0 0.8 0.1 0.1 2.1 0.0 0.8 0.0 0.1 3.5 2.1 0.3 0.0 5.1 0.7 3.6 0.1 15.8 0.2 0.0 3.7 0.3 1.9 0.1 5.4 3.9 6.4 10.2 0.2 0.2 4.5 2.5 1.2 2.4 3.1 2.5 3.1 46.7 3.0 1.3 1.1 10.6 12.9 0.6 2.2 11.8 4.2 7.4 10.7 2.8 0.0 5.4 9.3 0.0 0.1 1.7 0.2 0.3 0.7 21.4 5.8 38.9 1.1 3.2 24.3 5.0 1.4 5.8 1.9 26.4 13.7 15.7 0.9 1.4 8.3 11.6 4.3 5.4 1.3 0.8 4.0 3.9 0.5 2.2 6.1 7.0 3.6 28.5 37.2 38.0 2.1 5.8 4.3 4.1 0.2 0.8 0.0 0.6 0.0 0.4 0.3 0.2 0.5 0.3 0.0 0.0 0.1 0.1 0.9 0.4 1.3 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 3.4 0.8 0.2 0.2 1.8 0.0 1.0 1.3 0.6 0.0 0.3 1.8 0.0 3.4 0.7 14.5 0.0 0.1 50.2 0.3 0.3 0.6 1.2 45.7 0.1 0.0 4.8 1.1 3.1 1.1 0.0 4.2 0.4 0.4 2.3 0.0 0.1 5.9 0.0 3.1 0.8 110.3 0.3 2.7 0.0 1.0 1.4 0.0 0.0 0.5 0.1 0.1 7.3 0.4 14.5 0.6 1.8 0.1 0.0 0.0 0.0 0.1 0.8 2.5 5.2 10.2 1.0 0.5 1.7 0.7 9.5 1.3 EBP "CDPX2, CHO2, CPX, CPXD" ENSG00000147155 "EBP cholestenol delta-isomerase" Q15125 X 48521799-48528716 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Isomerase "Cataract, Disease variant, Dwarfism, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 328.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 674.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003130 Approved Supported "Endoplasmic reticulum" NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "HPA003130: AB_1078717" "unprognostic (1.90e-1)" "unprognostic (2.64e-2)" "unprognostic (2.80e-1)" "unprognostic (6.27e-2)" "unprognostic (3.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.13e-1)" "unprognostic (1.15e-1)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" "unprognostic (4.72e-2)" "unprognostic (1.47e-1)" "unprognostic (5.14e-2)" "unprognostic (4.04e-2)" "unprognostic (5.39e-2)" "unprognostic (4.13e-1)" "unprognostic (1.36e-1)" 10.2 73.3 16.7 17.1 17.2 48.3 17.4 18.5 17.8 19.4 22.0 50.6 85.5 11.0 17.3 41.3 14.3 10.5 32.5 16.8 18.7 44.0 328.5 24.4 18.8 24.4 16.6 12.7 26.0 44.0 7.2 8.2 24.2 40.6 57.5 10.7 25.0 11.7 9.5 27.8 54.2 14.9 15.8 16.9 31.6 14.2 15.9 28.2 14.4 10.6 32.7 14.1 23.3 16.0 224.5 96.4 107.4 77.0 74.5 39.2 50.5 48.2 43.6 64.3 93.9 169.9 382.7 115.9 35.2 41.3 83.5 230.3 217.5 293.8 49.8 85.8 149.7 50.1 115.2 139.3 57.8 179.2 138.2 51.3 108.6 112.9 86.4 22.5 46.5 98.1 77.6 119.5 50.7 163.7 119.1 199.9 118.2 88.3 199.1 93.8 10.3 363.7 175.6 68.8 110.0 59.6 175.4 122.6 31.2 91.5 122.9 71.1 46.6 33.1 56.2 132.9 63.1 47.5 72.1 107.7 78.7 239.7 40.6 96.1 37.7 97.1 129.4 53.4 104.5 71.5 90.5 116.7 53.5 57.2 76.5 99.7 7.3 63.9 57.2 105.4 103.1 93.6 16.7 17.2 18.5 17.8 16.8 18.7 24.4 16.6 24.2 15.8 15.9 16.0 15.2 32.1 49.8 2.9 38.9 37.1 58.2 245.6 23.3 23.8 57.8 26.2 49.9 77.2 116.6 53.3 8.4 55.9 74.5 140.3 39.2 91.7 10.5 30.5 14.7 26.1 30.0 48.8 7.4 239.1 113.0 21.4 36.2 56.5 40.6 41.2 27.1 674.6 65.0 8.4 10.3 96.8 93.6 30.2 36.0 11.8 13.4 31.9 37.4 4.7 34.8 19.3 101.0 5.0 5.1 156.7 137.3 14.7 54.4 46.4 171.9 99.7 34.8 23.3 13.1 12.5 23.6 8.7 22.7 47.6 45.5 37.5 57.1 128.7 149.1 71.1 ECT2 ARHGEF31 ENSG00000114346 "Epithelial cell transforming 2" Q9H8V3 3 172750682-172821474 "Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Neurogenesis, Protein transport, Transport" "Guanine-nucleotide releasing factor" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 64.6;Spermatocytes: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA036363, HPA053261" Enhanced Nucleoplasm,Cytosol No Yes "Cluster 1: Neutrophils - Mixed function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA036363: AB_2732472, HPA053261: AB_2682094" "unprognostic (3.83e-2)" "unprognostic (4.34e-1)" "unprognostic (1.27e-2)" "unprognostic (4.22e-3)" "unprognostic (4.49e-2)" "unprognostic (5.02e-3)" "prognostic unfavorable (6.82e-6)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.82e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (2.24e-5)" "unprognostic (2.44e-2)" "prognostic unfavorable (1.19e-5)" "unprognostic (1.08e-2)" "unprognostic (1.46e-1)" "unprognostic (1.29e-1)" "unprognostic (1.33e-1)" 3.6 3.3 2.1 8.2 1.9 19.8 7.5 3.4 3.4 8.1 1.4 11.5 9.3 4.4 1.8 8.9 3.3 5.3 3.2 2.4 1.4 4.3 2.6 5.2 10.5 2.1 1.7 1.3 2.9 3.6 1.2 8.8 2.7 3.2 15.8 12.5 5.6 2.6 2.1 7.1 7.6 7.5 0.7 4.3 9.4 15.9 2.3 23.3 3.9 2.7 11.4 6.9 4.2 3.5 192.0 133.6 103.2 54.0 10.6 21.8 51.6 81.5 67.5 121.4 116.9 74.7 196.9 47.2 122.1 48.8 116.0 81.8 84.2 53.1 164.3 67.8 46.6 29.6 70.0 38.5 4.6 46.2 32.8 7.1 9.0 72.2 73.2 34.0 53.0 68.6 31.3 67.2 97.2 67.6 47.5 34.6 84.4 156.7 72.0 33.7 101.1 60.7 92.2 43.7 68.6 44.1 104.5 117.4 42.2 51.5 195.4 34.1 46.5 58.5 55.7 79.6 174.9 32.8 47.2 88.2 51.6 39.7 78.0 6.0 2.0 0.7 1.0 1.7 1.1 1.4 1.4 0.9 1.6 1.3 0.6 0.9 6.3 0.7 0.7 1.6 2.5 0.7 2.1 1.9 3.4 3.4 2.4 1.4 2.1 1.7 2.7 0.7 2.3 3.5 6.7 6.4 3.2 4.2 3.8 19.5 4.9 6.2 9.1 3.4 10.1 6.5 3.6 5.7 5.7 3.7 64.6 12.0 2.9 10.7 0.0 9.5 3.3 20.1 6.6 7.7 4.8 25.2 6.5 9.2 14.9 6.0 17.9 20.5 0.0 17.9 5.3 2.9 7.3 0.0 2.5 13.5 10.2 4.7 6.3 2.8 0.9 5.1 7.2 15.0 2.8 3.1 2.1 3.0 4.9 20.7 3.8 1.5 9.6 12.8 1.5 3.7 11.0 16.3 0.0 2.9 5.2 42.6 30.4 16.9 12.8 3.8 4.1 3.3 13.5 8.8 EED "HEED, WAIT-1" ENSG00000074266 "Embryonic ectoderm development" O75530 11 86244753-86278813 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012211, HPA060089, HPA061140" Supported Supported Nucleoplasm NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 21: OE19 - Mitochondria" "Cluster 59: Non-specific - Transcription" Nucleoplasm "CAB012211: AB_2262066, HPA060089: AB_2684201, HPA061140: AB_2684437" "unprognostic (7.46e-2)" "unprognostic (4.40e-2)" "unprognostic (1.65e-1)" "unprognostic (1.02e-2)" "unprognostic (1.33e-1)" "unprognostic (3.13e-2)" "prognostic unfavorable (1.80e-5)" "unprognostic (2.90e-1)" "unprognostic (1.32e-2)" "unprognostic (2.39e-1)" "unprognostic (2.31e-1)" "unprognostic (9.19e-3)" "prognostic unfavorable (1.36e-7)" "unprognostic (1.67e-1)" "unprognostic (1.71e-1)" "unprognostic (1.33e-2)" "prognostic favorable (2.27e-5)" 9.3 9.0 13.2 16.3 13.1 9.2 11.4 15.0 15.8 13.8 13.1 12.1 12.1 11.5 15.2 12.7 10.6 9.3 8.9 12.8 13.5 11.5 11.9 8.5 28.8 12.9 12.8 12.1 10.5 9.1 9.4 14.5 13.1 11.7 11.9 16.4 10.3 10.6 10.5 12.1 11.6 10.2 12.9 14.4 10.9 10.3 13.6 17.8 10.7 11.1 32.1 13.0 12.1 13.9 34.2 37.8 40.9 16.8 22.6 20.2 47.0 49.2 22.6 46.3 46.8 121.0 64.4 79.8 50.6 15.8 44.2 41.4 48.7 26.8 43.2 79.7 22.7 51.4 38.7 36.3 19.8 54.2 33.4 12.4 18.0 46.8 20.1 17.5 20.9 34.7 58.8 16.2 39.0 55.2 51.5 55.4 30.4 107.8 18.4 56.2 49.1 38.8 29.1 55.4 27.5 22.4 63.5 29.6 14.5 29.1 49.2 22.6 19.0 48.1 44.1 70.0 43.2 9.2 32.1 63.9 13.7 46.6 36.8 31.0 9.1 15.0 25.4 15.3 22.1 45.0 33.2 32.0 13.9 47.3 26.4 29.6 3.9 19.3 16.8 9.2 58.6 19.1 13.2 13.1 15.0 15.8 12.8 13.5 12.9 12.8 13.1 12.9 13.6 13.9 15.4 6.4 9.3 28.1 32.7 25.6 11.6 27.5 25.0 26.4 13.3 11.8 9.5 11.5 15.4 7.3 18.8 45.2 31.0 16.1 19.6 14.5 7.7 17.6 17.1 16.6 7.2 15.8 35.0 10.2 36.8 14.8 16.3 15.5 15.9 15.0 13.2 11.4 16.9 32.0 45.6 12.8 12.2 14.5 32.5 3.6 22.7 15.2 19.6 37.5 30.4 11.5 25.7 31.2 38.9 11.9 11.1 17.3 17.6 11.9 11.7 8.6 21.3 18.3 6.6 14.3 24.5 18.7 20.0 16.9 16.8 24.9 31.6 17.5 15.0 20.9 EFNA1 "ECKLG, EPLG1, GMAN, LERK1, TNFAIP4" ENSG00000169242 "Ephrin A1" P20827 1 155127876-155134899 "Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 472.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 942.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "naive CD4 T-cell: 11.4;naive CD8 T-cell: 5.9" "Lineage enriched" "Detected in single" 23 "T-cells: 11.4" "Cell line enhanced" "Detected in many" "BEWO: 266.5;HaCaT: 95.5;SiHa: 156.9;SK-BR-3: 227.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069549 Approved "Secreted to blood" NA Yes 2800000 "Cluster 32: T-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA069549: " "unprognostic (5.14e-2)" "unprognostic (3.04e-3)" "unprognostic (5.03e-2)" "unprognostic (2.01e-1)" "unprognostic (1.59e-1)" "unprognostic (2.47e-2)" "unprognostic (1.78e-2)" "unprognostic (5.80e-3)" "unprognostic (1.53e-1)" "unprognostic (4.56e-2)" "unprognostic (2.00e-2)" "unprognostic (2.23e-1)" "unprognostic (4.44e-2)" "unprognostic (3.58e-1)" "unprognostic (1.93e-1)" "unprognostic (2.41e-1)" "unprognostic (1.32e-1)" 43.2 24.0 25.6 4.9 30.0 1.3 64.7 27.2 33.9 31.7 21.8 42.5 57.9 23.7 28.5 54.7 23.2 24.5 47.1 25.5 25.9 73.8 472.8 86.7 8.1 31.0 29.0 17.5 53.6 29.7 19.5 109.9 29.8 79.5 51.6 7.8 66.6 22.1 18.5 123.1 69.3 13.4 27.8 8.6 40.7 4.1 27.6 21.0 79.9 38.6 12.5 36.9 55.5 35.2 15.1 5.9 0.9 11.5 2.1 0.1 266.5 0.0 0.5 0.2 0.3 13.9 32.0 0.0 26.3 0.0 9.0 95.5 6.6 35.3 0.2 9.8 2.2 0.1 19.0 76.1 0.9 0.2 1.5 4.9 84.5 0.0 30.2 7.3 53.6 0.9 2.8 0.3 0.0 52.2 0.3 1.1 1.7 52.3 17.7 6.1 1.5 9.3 66.4 22.4 9.8 14.2 156.9 227.1 6.0 48.8 51.1 0.0 6.7 0.1 9.1 0.6 1.5 2.3 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 1.0 0.7 0.0 0.3 11.4 5.9 0.4 0.4 0.0 0.0 0.0 1.6 25.6 30.0 27.2 33.9 25.5 25.9 31.0 29.0 29.8 27.8 27.6 35.2 116.8 198.7 113.1 0.7 2.3 127.7 103.7 91.6 327.8 3.0 198.3 151.9 47.8 95.8 101.2 18.4 0.0 195.6 4.4 265.0 13.7 130.1 0.3 100.4 19.1 148.9 18.6 4.0 0.7 63.9 942.6 23.2 124.9 163.5 6.3 0.1 106.4 133.2 28.2 5.0 0.8 114.1 101.7 4.3 19.5 0.7 4.7 4.2 62.2 2.8 0.6 5.7 0.0 3.5 28.7 73.9 205.5 0.4 4.1 197.8 238.6 34.5 54.5 1.1 0.0 6.5 35.9 0.8 2.6 253.2 217.8 254.2 7.5 1.3 95.9 135.9 EFNA5 "AF1, EPLG7, LERK7" ENSG00000184349 "Ephrin A5" P52803 5 107376894-107670937 "Cancer-related genes, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 13 "Astrocytes: 291.2;Excitatory neurons: 798.5;Inhibitory neurons: 373.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 35.2;RPTEC TERT1: 50.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013282, HPA054047" Approved Approved Vesicles,Cytosol NA Yes 10000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Cytosol" "CAB013282: AB_2533353, HPA054047: AB_2682355" "unprognostic (1.67e-1)" "unprognostic (4.04e-2)" "unprognostic (7.52e-2)" "unprognostic (2.15e-3)" "unprognostic (3.98e-3)" "unprognostic (2.74e-2)" "unprognostic (8.91e-4)" "unprognostic (9.46e-3)" "unprognostic (4.92e-1)" "unprognostic (2.28e-3)" "unprognostic (1.26e-3)" "unprognostic (1.47e-1)" "prognostic unfavorable (1.92e-7)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.52e-1)" "unprognostic (2.13e-2)" "unprognostic (1.27e-1)" 4.1 1.1 4.5 2.0 6.5 0.1 4.0 1.3 13.6 10.1 0.0 2.3 0.8 1.1 2.0 7.1 2.9 2.7 6.8 3.1 10.2 3.4 0.3 2.4 0.8 0.9 0.3 4.0 0.5 2.5 2.7 2.4 0.6 4.3 2.3 2.5 5.6 4.7 0.5 9.7 0.8 2.2 0.0 5.3 2.5 1.4 2.1 1.4 1.0 1.4 2.5 3.5 4.8 5.4 12.7 22.2 35.2 0.0 16.7 14.2 3.6 0.3 6.3 4.5 11.6 0.2 13.9 0.0 20.5 2.4 7.1 13.1 19.4 18.0 3.6 0.0 12.9 0.1 11.9 0.0 3.1 0.6 0.0 16.0 15.4 0.0 14.4 3.9 13.8 0.0 0.0 0.0 8.3 12.0 0.0 0.0 4.6 0.1 1.9 0.0 16.9 0.4 50.9 15.5 5.8 14.7 6.0 8.9 3.8 11.2 3.9 2.2 0.2 28.3 5.0 17.4 7.1 1.2 0.0 8.3 12.4 0.8 31.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.4 0.1 0.7 0.0 0.0 0.0 0.1 4.5 6.5 1.3 13.6 3.1 10.2 0.9 0.3 0.6 0.0 2.1 5.4 1.1 9.6 24.4 291.2 0.0 15.9 22.5 18.5 6.2 4.3 11.8 8.5 30.6 11.5 26.0 14.7 0.0 20.3 3.3 4.3 23.5 1.7 1.8 3.2 14.8 8.2 12.0 0.0 798.5 1.3 3.3 16.9 5.6 6.3 0.0 0.1 9.7 0.0 1.7 6.7 373.1 8.5 18.3 0.3 7.0 3.7 18.3 0.4 8.8 37.5 3.6 4.7 2.1 26.2 8.7 13.9 4.9 21.8 1.7 14.1 0.0 0.1 19.6 1.4 0.0 1.3 3.7 0.1 4.0 14.9 24.2 3.8 2.2 2.3 5.9 23.1 EID1 "C15orf3, CRI1, EID-1" ENSG00000255302 "EP300 interacting inhibitor of differentiation 1" Q9Y6B2 15 48878134-48880173 "Predicted intracellular proteins" "Cell cycle, Differentiation, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA051122, HPA051123" Approved Supported Nucleoplasm NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 38: Heart - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA051122: AB_2681350, HPA051123: AB_2681351" "unprognostic (1.38e-1)" "unprognostic (6.69e-2)" "unprognostic (1.64e-1)" "unprognostic (3.18e-2)" "unprognostic (7.81e-2)" "prognostic unfavorable (9.99e-4)" "unprognostic (1.10e-1)" "unprognostic (2.79e-2)" "unprognostic (1.39e-1)" "unprognostic (1.41e-1)" "unprognostic (6.75e-3)" "unprognostic (2.46e-1)" "unprognostic (3.62e-3)" "prognostic unfavorable (2.91e-4)" "unprognostic (2.04e-2)" "unprognostic (2.13e-1)" "unprognostic (2.09e-1)" 128.6 206.3 96.9 95.4 103.7 61.0 112.0 98.7 153.6 149.8 107.2 143.9 81.6 161.0 132.1 96.6 134.9 120.9 280.1 103.9 111.3 147.9 125.1 99.5 112.0 102.6 101.7 186.7 102.0 144.8 130.1 93.3 100.5 156.1 71.3 158.4 98.3 147.3 278.8 57.6 79.0 141.8 102.1 115.3 84.2 67.9 104.5 117.2 138.5 227.6 83.9 113.1 81.4 123.2 131.5 109.1 260.9 231.6 239.9 316.9 16.4 337.6 304.5 220.3 294.3 95.0 58.0 174.9 305.3 207.0 155.5 115.4 130.2 130.8 247.9 484.1 127.1 300.6 235.8 4.1 186.0 183.0 132.2 278.1 115.1 146.1 91.9 221.4 262.8 151.2 182.3 162.6 258.5 188.7 134.6 174.1 0.5 98.9 97.4 185.1 302.6 290.6 287.4 142.3 233.8 234.6 210.2 80.2 401.2 212.7 145.0 240.6 262.9 322.4 177.7 305.6 299.3 208.4 616.7 125.1 264.6 410.0 230.0 345.0 311.5 275.5 221.3 285.3 209.2 168.3 249.4 231.8 358.1 183.2 179.6 165.3 40.4 230.0 297.5 354.9 332.4 440.1 96.9 103.7 98.7 153.6 103.9 111.3 102.6 101.7 100.5 102.1 104.5 123.2 327.4 387.8 207.7 31.3 127.5 175.5 139.9 459.5 138.9 345.3 188.5 286.4 480.8 183.0 329.9 261.1 120.9 351.6 168.0 46.0 606.5 386.5 17.5 116.0 324.4 356.8 233.7 219.2 38.0 268.0 151.2 443.4 88.2 116.7 188.0 173.8 339.8 166.2 211.3 238.9 43.5 114.0 301.1 208.1 262.0 49.2 702.4 189.7 487.4 30.9 302.2 844.1 213.1 28.6 80.9 191.0 102.1 651.4 134.3 81.4 91.9 446.5 240.2 329.9 322.1 350.7 379.1 98.6 75.0 125.9 145.6 109.6 180.7 463.2 101.5 96.9 EIF5B "DKFZp434I036, FLJ10524, IF2, KIAA0741" ENSG00000158417 "Eukaryotic translation initiation factor 5B" O60841 2 99337371-99401326 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Hydrolase, Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 769.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034648, HPA040095" Approved Approved "Plasma membrane,Cytosol" NA Yes 210000 "Cluster 6: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Plasma membrane" "HPA034648: AB_10601902, HPA040095: AB_2676843" "unprognostic (1.23e-1)" "unprognostic (6.94e-2)" "unprognostic (2.01e-1)" "unprognostic (5.03e-2)" "unprognostic (4.65e-2)" "unprognostic (5.88e-3)" "prognostic unfavorable (7.15e-10)" "unprognostic (6.80e-2)" "unprognostic (9.84e-3)" "prognostic favorable (8.99e-4)" "unprognostic (1.68e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (1.42e-6)" "unprognostic (6.89e-2)" "unprognostic (3.24e-2)" "unprognostic (1.43e-1)" "unprognostic (7.93e-3)" 39.4 31.6 50.3 32.8 53.5 20.8 33.9 50.8 88.8 31.3 51.1 56.3 23.1 35.2 41.7 44.4 29.6 18.5 89.6 48.8 55.3 50.9 38.4 30.9 32.6 54.1 52.5 27.0 48.6 32.1 28.2 29.6 55.0 44.0 30.0 23.8 36.5 33.5 102.9 39.4 29.1 28.7 52.8 30.7 42.1 48.6 53.6 26.2 29.3 56.2 36.6 47.8 33.7 53.0 117.0 57.2 63.8 83.5 75.5 88.7 105.4 100.4 62.9 65.3 64.6 132.5 80.9 132.5 84.6 75.2 77.4 64.9 112.6 97.3 114.6 80.8 67.4 159.6 57.7 175.9 59.7 158.0 94.3 60.2 66.8 91.0 92.1 55.9 96.6 80.0 179.6 64.4 95.2 94.9 100.8 145.7 99.5 76.2 83.0 86.8 94.7 108.2 134.9 96.2 53.8 50.9 54.6 123.8 85.3 120.4 50.5 103.0 106.9 100.7 99.3 53.2 90.7 47.4 72.0 106.0 73.3 172.0 75.9 19.8 11.0 13.7 15.5 12.5 18.2 20.9 16.3 15.5 8.4 19.8 15.9 17.0 2.9 18.3 17.3 26.2 12.5 6.4 50.3 53.5 50.8 88.8 48.8 55.3 54.1 52.5 55.0 52.8 53.6 53.0 121.7 109.0 219.6 23.8 152.4 321.3 200.4 209.0 84.8 103.8 159.1 112.1 579.1 135.8 198.6 343.9 50.1 143.7 142.9 135.0 144.8 210.5 769.9 143.1 175.0 153.2 157.9 154.2 27.4 235.1 205.3 130.4 82.0 157.5 172.7 90.0 146.3 480.9 134.7 77.4 28.3 206.7 144.5 123.5 128.9 144.0 124.5 95.7 142.3 18.7 157.7 91.8 145.2 21.6 36.7 282.6 93.8 175.7 183.2 253.9 102.7 226.2 165.4 111.3 276.1 167.3 157.7 575.3 505.0 99.1 324.8 181.4 133.4 101.7 185.1 244.7 ERH DROER ENSG00000100632 "ERH mRNA splicing and mitosis factor" P84090 14 69380128-69398299 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002567 Approved Approved Nucleoplasm,Cytosol NA Yes 190000 "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "HPA002567: AB_1078749" "unprognostic (2.42e-2)" "unprognostic (1.69e-1)" "unprognostic (3.42e-1)" "unprognostic (4.78e-2)" "unprognostic (9.34e-2)" "unprognostic (8.61e-3)" "prognostic unfavorable (7.89e-5)" "unprognostic (1.93e-1)" "unprognostic (1.06e-1)" "unprognostic (8.83e-3)" "unprognostic (2.31e-1)" "unprognostic (9.24e-2)" "unprognostic (2.49e-1)" "unprognostic (1.12e-1)" "unprognostic (9.32e-2)" "unprognostic (4.31e-2)" "unprognostic (2.39e-1)" 107.7 113.7 143.3 119.0 146.2 144.4 119.3 145.1 186.7 97.0 146.9 110.5 110.0 111.9 150.3 75.5 112.8 70.1 100.2 145.4 159.1 118.3 142.5 76.3 147.1 142.8 146.8 107.0 66.7 128.2 58.3 98.1 147.6 87.0 122.9 116.7 110.0 84.3 107.0 58.1 99.1 114.8 153.7 96.5 88.7 91.1 149.6 212.2 97.6 85.8 168.4 117.0 51.2 154.5 972.7 574.9 704.6 409.1 271.8 201.1 356.9 450.7 261.3 401.3 372.0 598.5 403.1 879.9 224.3 305.3 340.3 296.1 563.4 376.9 484.2 437.9 428.3 441.4 366.1 731.8 419.6 389.3 334.6 227.1 203.0 355.9 317.2 239.2 337.8 584.5 454.0 301.6 335.7 1043.2 714.1 750.8 537.2 525.6 686.0 558.9 599.9 320.6 415.4 672.8 449.1 439.8 442.1 464.6 355.6 330.8 539.9 564.4 351.4 425.7 699.7 286.7 480.0 351.7 336.2 1096.1 345.1 417.5 442.4 76.6 101.4 80.9 76.6 98.9 77.5 122.2 100.0 88.0 107.4 94.3 92.7 88.2 45.3 121.5 95.1 122.8 116.5 147.0 143.3 146.2 145.1 186.7 145.4 159.1 142.8 146.8 147.6 153.7 149.6 154.5 231.2 60.9 54.3 22.2 189.1 273.1 225.0 702.7 180.4 126.4 244.2 314.2 118.9 181.6 282.2 253.8 37.5 455.3 179.4 117.5 673.1 363.8 100.4 238.1 198.9 211.9 188.5 252.6 23.9 275.3 560.3 237.0 120.3 158.7 127.6 186.7 169.6 239.9 341.5 74.0 23.1 244.0 510.6 147.5 215.2 51.3 270.9 162.5 307.7 16.9 302.3 350.3 174.0 19.6 34.6 289.8 183.9 259.2 237.9 288.9 203.9 508.5 278.4 119.8 190.7 177.7 273.8 321.5 230.9 251.0 318.8 279.9 165.3 281.4 265.9 230.6 ERN1 "IRE1, IRE1P" ENSG00000178607 "Endoplasmic reticulum to nucleus signaling 1" O75460 17 64039080-64130819 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Transcription, Transcription regulation, Unfolded protein response" "Hydrolase, Kinase, Multifunctional enzyme, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 53.0;pancreas: 66.7" "Cell type enhanced" "Detected in many" "Plasma cells: 325.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 17.9" "Group enriched" "Detected in many" 5 "dendritic cells: 7.7;granulocytes: 17.9;T-cells: 9.0" "Cell line enhanced" "Detected in many" "Karpas-707: 74.6;RPMI-8226: 40.2;U-266/70: 77.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009495, HPA027730" Supported NA Yes "Cluster 38: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB009495: AB_2098712, HPA027730: AB_10602494" "unprognostic (2.52e-1)" "unprognostic (1.16e-2)" "unprognostic (1.89e-1)" "unprognostic (4.05e-3)" "unprognostic (3.63e-2)" "unprognostic (2.81e-2)" "unprognostic (9.14e-2)" "unprognostic (2.72e-2)" "unprognostic (4.55e-1)" "unprognostic (6.17e-2)" "unprognostic (2.95e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.68e-4)" "unprognostic (4.65e-1)" "unprognostic (1.89e-1)" "unprognostic (1.36e-2)" "unprognostic (3.11e-2)" 9.5 53.0 1.5 5.4 1.7 13.4 7.5 2.6 3.2 22.6 2.1 7.7 6.3 10.1 6.4 9.5 14.3 6.2 6.1 1.6 2.4 5.6 23.5 16.5 5.8 1.7 1.0 16.9 66.7 4.3 19.5 5.6 1.3 9.9 4.5 8.8 15.7 7.1 6.8 11.3 10.6 5.6 1.0 15.8 16.2 2.8 1.6 6.8 10.2 2.4 6.6 8.3 11.7 1.7 4.0 4.0 2.2 4.8 4.8 4.4 9.8 4.1 9.7 2.8 1.3 2.5 2.3 6.6 3.2 2.8 3.5 3.6 1.9 4.5 6.1 1.6 1.5 6.0 3.2 2.4 19.6 3.2 2.1 3.8 8.1 6.4 21.5 3.5 5.0 4.7 4.2 74.6 2.8 3.9 4.5 1.0 0.6 3.6 3.2 4.2 4.2 40.2 1.1 5.5 7.1 3.5 4.3 6.1 5.7 3.5 3.8 5.9 5.9 2.5 4.1 6.4 2.7 77.4 23.9 4.8 4.0 2.1 4.2 17.9 0.9 0.4 4.9 0.4 9.0 0.2 3.3 4.1 0.4 0.3 0.9 0.9 4.9 2.5 0.3 7.7 0.8 1.0 1.5 1.7 2.6 3.2 1.6 2.4 1.7 1.0 1.3 1.0 1.6 1.7 31.9 0.0 36.1 7.2 27.8 22.0 54.3 8.3 15.4 4.0 35.0 29.7 8.6 11.5 8.6 12.9 6.2 8.1 106.4 10.0 1.9 12.6 2.3 26.1 49.1 18.3 79.7 11.2 8.6 27.3 8.8 42.2 52.0 79.4 8.2 11.8 13.9 26.8 8.0 3.3 6.1 8.2 8.2 15.7 71.3 1.7 4.7 60.4 74.7 12.2 10.2 3.5 28.8 6.0 4.6 17.9 7.3 6.0 325.8 44.7 7.9 4.4 6.1 26.5 0.0 19.0 25.7 4.0 4.1 27.7 45.0 54.9 88.2 12.0 9.6 60.1 FAM111B CANP ENSG00000189057 "Family with sequence similarity 111 member B" Q6SJ93 11 59107185-59127412 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 18.0" "Cell type enhanced" "Detected in many" "B-cells: 12.8;Erythroid cells: 9.1;Plasma cells: 8.8;Squamous epithelial cells: 7.1;Undifferentiated cells: 10.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory B-cell: 3.3;naive B-cell: 2.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA038637 Uncertain Approved Nucleoplasm,Cytosol No Yes "Cluster 37: B-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm Cytosol "HPA038637: AB_10672522" "unprognostic (2.31e-1)" "unprognostic (2.68e-2)" "unprognostic (1.80e-3)" "unprognostic (6.94e-2)" "unprognostic (1.89e-1)" "unprognostic (1.96e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (1.49e-3)" "unprognostic (1.40e-2)" "unprognostic (4.85e-2)" "prognostic unfavorable (1.17e-5)" "unprognostic (1.01e-2)" "unprognostic (1.24e-5)" "unprognostic (2.94e-2)" "unprognostic (1.80e-1)" "unprognostic (1.20e-3)" "unprognostic (1.24e-1)" 0.9 0.5 0.5 5.9 0.6 4.8 2.7 2.8 1.8 1.0 0.1 5.6 3.4 1.0 0.5 3.4 0.5 0.8 0.3 0.6 1.1 0.4 2.5 1.1 12.3 0.5 1.0 0.2 0.6 0.9 0.0 1.7 0.7 1.0 5.8 1.3 0.8 0.4 0.4 4.4 4.0 2.0 0.1 1.8 3.2 0.8 0.6 18.0 0.9 0.1 13.3 1.7 1.0 2.1 72.6 18.5 26.6 0.4 2.7 4.9 0.3 53.5 26.7 31.2 46.1 38.7 28.0 89.8 35.4 15.7 26.3 54.7 39.5 36.2 55.2 46.8 9.5 9.8 32.3 16.9 0.1 0.3 11.1 1.2 1.2 30.3 2.4 6.0 16.9 24.1 2.8 81.9 37.2 27.3 57.7 0.6 0.3 43.2 21.0 60.1 39.7 34.7 16.8 61.2 5.2 16.9 44.4 50.8 8.7 9.7 56.2 5.0 9.4 24.1 52.4 73.5 49.6 62.6 48.4 0.6 35.0 0.4 35.4 0.2 0.1 0.1 0.1 0.0 0.1 3.3 0.2 0.3 0.1 2.6 0.1 0.1 1.6 0.0 0.1 0.1 0.7 0.1 0.5 0.6 2.8 1.8 0.6 1.1 0.5 1.0 0.7 0.1 0.6 2.1 0.7 0.0 0.0 0.0 12.8 4.2 2.2 4.2 1.8 0.0 2.5 4.2 0.3 0.0 1.4 0.0 0.0 1.1 1.4 4.0 0.0 0.8 0.0 0.9 1.6 1.2 0.0 9.1 0.0 0.0 0.4 1.5 3.6 1.9 0.0 6.3 0.0 0.2 3.9 0.0 0.0 4.4 2.0 0.3 1.6 0.0 0.0 2.4 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.6 1.3 0.0 8.8 0.7 0.5 0.1 1.6 0.0 0.0 1.3 1.8 0.1 1.0 7.1 2.7 0.1 3.2 1.1 10.4 1.6 FAM161A "FLJ13305, RP28" ENSG00000170264 "FAM161 centrosomal protein A" Q3B820 2 61824848-61854143 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Sensory transduction, Vision" "Ciliopathy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 28.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 100.1;Early spermatids: 183.2;Late spermatids: 293.1;Rod photoreceptor cells: 417.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032119 Approved NA Yes "Cluster 49: Eosinophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA032119: AB_10602806" "unprognostic (1.14e-1)" "unprognostic (1.36e-1)" "unprognostic (4.23e-2)" "prognostic unfavorable (9.02e-4)" "unprognostic (1.73e-1)" "unprognostic (2.16e-1)" "unprognostic (1.56e-5)" "unprognostic (7.62e-2)" "unprognostic (1.72e-1)" "unprognostic (2.14e-2)" "unprognostic (4.35e-2)" "unprognostic (2.00e-2)" "unprognostic (1.66e-1)" "unprognostic (5.33e-2)" "unprognostic (3.93e-1)" "unprognostic (8.08e-3)" "unprognostic (7.04e-2)" 0.9 1.2 0.8 0.5 1.1 0.3 1.1 0.6 1.6 2.1 2.4 1.0 0.4 1.6 1.2 1.1 4.0 1.4 1.5 0.9 1.1 1.9 0.7 1.0 0.7 0.8 0.9 5.2 2.3 1.9 2.4 1.1 0.8 1.0 0.6 28.9 0.7 1.1 1.2 0.6 0.7 0.6 0.6 0.7 2.6 5.5 1.0 1.6 3.6 0.3 0.6 1.1 1.1 0.9 3.4 3.1 7.1 3.3 3.4 3.2 2.1 2.9 1.5 3.4 4.2 2.1 1.7 6.6 1.5 0.5 6.1 1.6 4.3 0.5 8.0 4.5 4.7 2.4 2.8 3.3 2.9 2.7 0.5 1.3 0.0 6.6 1.9 4.0 3.7 6.4 0.9 2.5 2.4 1.3 4.9 5.2 11.0 4.2 3.3 8.4 12.1 3.3 2.4 0.8 8.7 7.3 6.2 0.8 4.7 6.7 1.5 1.8 0.7 5.9 5.2 4.2 6.7 3.8 3.1 8.1 4.2 4.5 1.2 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.8 1.1 0.6 1.6 0.9 1.1 0.8 0.9 0.8 0.6 1.0 0.9 3.9 3.2 9.7 20.2 3.7 5.5 9.4 10.2 6.2 49.7 4.8 7.0 14.5 7.2 10.5 20.2 100.1 14.0 2.3 1.5 1.9 4.3 183.2 42.7 11.0 6.7 6.0 5.5 16.6 3.8 7.7 10.7 5.1 4.8 4.5 42.7 4.2 3.8 3.6 16.8 19.0 2.5 14.2 1.2 3.6 293.1 20.8 2.3 8.8 4.7 2.0 42.4 2.1 11.1 33.0 1.3 0.3 16.6 4.0 4.7 0.0 13.0 47.1 417.2 0.0 14.2 9.0 98.0 39.3 5.3 4.1 11.1 3.6 16.4 3.5 3.4 FANCL "FAAP43, FLJ10335, PHF9, Pog" ENSG00000115392 "FA complementation group L" Q9NW38 2 58159243-58241372 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 81.4;Oligodendrocytes: 188.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033842, HPA036685, HPA036686" Supported Approved "Nuclear bodies,Vesicles" NA Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear bodies" Vesicles "CAB033842: AB_1122766, HPA036685: AB_10672474, HPA036686: AB_10670844" "unprognostic (3.02e-1)" "unprognostic (5.52e-2)" "unprognostic (2.19e-1)" "unprognostic (2.02e-3)" "unprognostic (6.24e-2)" "unprognostic (2.92e-2)" "prognostic unfavorable (2.81e-7)" "unprognostic (4.71e-2)" "unprognostic (2.63e-2)" "unprognostic (1.31e-2)" "unprognostic (3.50e-1)" "unprognostic (1.17e-2)" "prognostic unfavorable (1.12e-7)" "unprognostic (1.50e-1)" "unprognostic (1.39e-1)" "unprognostic (9.08e-3)" "prognostic favorable (7.80e-5)" 8.5 35.3 39.4 11.0 49.5 15.1 19.5 35.3 39.4 18.6 27.2 12.1 11.5 19.9 18.4 11.5 13.9 12.0 13.0 34.1 45.1 12.2 21.7 9.6 14.8 51.6 40.3 24.8 14.5 14.0 44.3 12.5 55.4 14.7 14.8 24.6 18.7 10.7 9.1 17.9 12.8 13.5 40.9 16.8 13.1 19.1 41.2 13.2 17.1 9.1 12.6 11.7 14.6 68.6 48.6 35.0 69.4 34.0 11.9 15.1 36.9 34.8 21.5 33.8 43.5 30.9 59.4 33.4 43.8 11.4 46.3 27.5 39.0 26.4 56.0 78.8 61.7 54.8 49.5 42.1 13.0 53.3 29.0 11.8 12.4 24.8 9.7 29.9 27.0 23.5 51.9 29.6 23.2 24.6 18.9 65.8 75.2 77.4 7.2 35.2 52.5 26.1 29.9 47.2 78.1 39.3 49.5 20.2 33.8 37.0 18.7 35.4 15.9 30.0 45.0 22.3 39.0 30.4 20.6 19.7 63.7 35.7 46.6 3.2 3.0 4.9 3.7 5.6 3.0 9.1 3.2 4.2 5.9 9.3 1.0 2.3 0.8 7.6 4.3 5.3 4.8 2.2 39.4 49.5 35.3 39.4 34.1 45.1 51.6 40.3 55.4 40.9 41.2 68.6 16.7 19.2 20.0 18.6 9.4 10.3 13.9 26.1 11.4 16.6 12.5 15.4 16.4 8.6 16.1 9.2 4.2 29.1 4.8 7.2 11.7 9.7 2.5 11.1 15.8 14.8 9.0 14.5 45.0 4.2 14.0 12.2 15.3 6.2 10.8 25.8 13.2 12.5 10.9 8.4 38.4 15.0 30.5 6.3 4.6 3.6 10.8 7.0 26.6 34.7 6.8 22.8 3.1 81.4 188.9 4.6 13.3 14.3 9.7 6.2 21.7 5.7 23.2 18.7 13.1 10.8 12.4 52.6 37.9 9.5 6.8 7.4 5.6 13.2 16.0 9.3 FSCN1 "FLJ38511, p55, SNL" ENSG00000075618 "Fascin actin-bundling protein 1" Q16658 7 5592816-5606655 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 256.5;Hofbauer cells: 274.2;monocytes: 1028.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 2.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 600.3;Hep G2: 464.9;K-562: 533.6;NB-4: 600.9;PC-3: 508.2;SH-SY5Y: 482.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000121, HPA005723, CAB035991, HPA050654" Enhanced Supported "Plasma membrane,Cytosol" NA Yes 4300000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 3: Monocytes - Immune response regulation" Cytosol "Plasma membrane" "CAB000121: AB_2278596, CAB035991: , HPA005723: AB_1849159, HPA050654: AB_2681203" "unprognostic (1.91e-1)" "unprognostic (2.03e-2)" "unprognostic (3.12e-2)" "unprognostic (5.00e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (5.76e-4)" "unprognostic (2.16e-3)" "prognostic unfavorable (2.28e-4)" "unprognostic (6.31e-2)" "unprognostic (1.25e-1)" "unprognostic (3.27e-3)" "unprognostic (1.54e-1)" "prognostic unfavorable (8.15e-7)" "unprognostic (1.21e-2)" "unprognostic (8.57e-2)" "unprognostic (1.05e-2)" "unprognostic (6.93e-3)" 27.5 39.7 41.5 31.1 62.2 8.3 24.9 26.3 57.2 33.7 10.7 12.1 4.4 19.7 0.7 69.4 15.6 7.6 15.8 39.4 28.2 17.3 8.3 27.6 14.5 49.4 42.7 47.7 5.5 2.3 20.2 27.9 22.8 10.3 1.7 3.4 23.8 2.4 7.3 56.3 12.6 5.7 20.9 55.6 9.3 42.5 79.0 9.0 25.6 2.1 8.3 20.4 41.6 77.1 62.3 139.3 91.2 326.3 34.8 65.4 600.3 144.2 62.4 24.2 26.1 98.5 15.6 1.3 172.0 63.5 24.3 231.3 52.2 229.9 2.1 70.6 28.7 4.8 142.0 464.9 18.0 0.2 13.9 40.8 66.6 46.1 37.2 40.4 118.3 0.7 533.6 0.9 31.6 6.9 2.0 600.9 238.4 4.2 508.2 140.0 22.3 2.3 34.9 5.9 73.1 482.4 121.0 2.6 5.3 58.5 3.9 38.4 246.4 167.4 289.3 99.1 151.0 0.9 0.8 0.7 107.8 0.6 317.2 0.0 0.8 0.0 0.0 0.2 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.7 41.5 62.2 26.3 57.2 39.4 28.2 49.4 42.7 22.8 20.9 79.0 77.1 90.0 3.2 4.1 1.6 8.3 181.2 26.7 75.1 189.5 9.4 32.3 44.3 10.4 1.5 13.4 1.8 0.0 6.7 10.8 3.9 0.0 12.8 14.3 8.0 37.8 120.6 42.1 28.0 12.1 5.1 110.8 48.9 10.7 10.1 16.5 256.5 84.6 0.8 274.2 0.0 10.9 5.4 8.2 28.0 136.1 12.3 25.4 27.4 51.6 23.4 1028.2 73.5 0.0 4.5 43.2 15.5 1.1 9.1 4.2 7.5 0.4 0.4 2.9 2.6 0.0 29.7 46.3 5.7 8.0 121.2 147.2 14.6 12.2 8.3 2.6 28.0 GADD45A "DDIT1, GADD45" ENSG00000116717 "Growth arrest and DNA damage inducible alpha" P24522 1 67685201-67688334 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, Growth arrest" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 240.5" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 858.9;Basal prostatic cells: 2807.1;Glandular and luminal cells: 982.6;Urothelial cells: 1740.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 48.4" "Group enriched" "Detected in all" 5 "granulocytes: 48.4;T-cells: 18.6" "Cell line enhanced" "Detected in all" "HHSteC: 365.9;hTERT-HME1: 577.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053420 Supported "Nuclear speckles" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear speckles" "HPA053420: AB_2682144" "unprognostic (1.36e-2)" "unprognostic (3.29e-2)" "unprognostic (9.58e-2)" "unprognostic (3.76e-3)" "unprognostic (5.81e-2)" "unprognostic (1.36e-2)" "unprognostic (1.57e-3)" "unprognostic (2.80e-3)" "unprognostic (1.42e-1)" "unprognostic (6.26e-2)" "unprognostic (3.43e-2)" "unprognostic (5.21e-2)" "prognostic favorable (8.06e-6)" "unprognostic (6.11e-2)" "unprognostic (2.89e-1)" "unprognostic (3.43e-3)" "unprognostic (1.93e-1)" 122.0 15.9 21.0 20.0 24.7 136.2 83.7 19.2 27.5 65.6 22.3 29.6 24.8 69.5 23.3 39.2 42.3 44.2 62.2 20.8 24.0 147.2 164.9 75.0 13.7 34.7 26.8 49.6 20.2 19.5 19.1 22.2 24.6 25.6 21.2 19.0 32.4 36.9 240.5 57.9 32.2 38.3 18.6 26.8 53.2 12.3 25.3 30.7 73.8 26.4 16.8 50.4 44.4 28.7 138.6 9.7 22.3 7.5 44.8 43.9 219.8 239.5 122.6 88.5 96.7 50.8 25.3 61.1 71.4 42.0 206.6 85.3 3.0 219.6 164.5 44.9 23.6 75.7 24.0 51.8 365.9 22.5 7.5 76.7 117.8 107.7 577.7 41.5 61.0 15.2 165.6 109.9 104.5 4.8 7.2 27.3 29.8 19.3 96.3 16.4 177.2 67.9 44.2 110.5 102.7 17.1 51.9 15.2 158.3 79.7 2.6 23.2 61.6 85.7 111.6 89.3 165.7 267.3 54.9 106.8 37.8 11.1 86.3 23.6 5.7 48.4 6.3 2.8 5.3 2.3 4.4 5.3 2.6 1.5 1.2 2.0 8.2 6.5 2.0 4.1 18.6 8.7 21.0 24.7 19.2 27.5 20.8 24.0 34.7 26.8 24.6 18.6 25.3 28.7 402.5 64.1 19.0 6.8 51.2 858.9 2807.1 273.2 225.3 45.1 56.7 100.6 190.5 47.1 155.8 103.0 10.4 24.6 85.1 175.3 236.7 264.4 1.6 410.7 250.6 176.6 131.7 116.2 6.1 253.6 117.8 177.0 87.7 982.6 44.5 18.9 74.6 110.1 18.6 26.9 7.0 99.6 122.1 23.5 290.6 4.0 38.2 94.7 158.3 7.5 273.2 30.3 12.3 6.6 1.0 367.3 202.0 64.7 116.8 786.2 101.4 530.0 135.1 72.8 52.6 136.0 201.6 3.7 18.8 365.2 390.8 17.6 139.5 88.6 70.3 1740.4 GAR1 NOLA1 ENSG00000109534 "GAR1 ribonucleoprotein" Q9NY12 4 109815510-109824740 "Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059098 Supported Approved "Nucleoplasm,Nucleoli fibrillar center" NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli fibrillar center" "HPA059098: AB_2683904" "unprognostic (9.72e-2)" "unprognostic (6.94e-2)" "unprognostic (3.04e-2)" "unprognostic (4.47e-2)" "unprognostic (2.40e-1)" "unprognostic (1.24e-2)" "prognostic unfavorable (2.64e-5)" "unprognostic (1.01e-2)" "unprognostic (1.73e-1)" "unprognostic (4.17e-3)" "unprognostic (2.14e-2)" "unprognostic (2.45e-3)" "unprognostic (1.17e-1)" "unprognostic (5.11e-2)" "unprognostic (1.11e-1)" "unprognostic (6.49e-2)" "unprognostic (1.08e-3)" 14.7 16.4 10.0 13.5 10.1 31.7 15.9 9.8 13.0 12.3 10.1 16.0 11.3 13.7 11.4 23.0 13.3 6.4 12.7 10.0 10.3 20.1 16.5 9.6 13.5 10.1 10.1 15.5 14.7 9.3 11.8 11.5 10.3 12.2 15.2 7.1 13.2 8.0 12.2 23.2 13.2 11.7 9.9 15.5 12.9 15.1 10.3 13.8 10.7 6.6 16.0 16.3 13.5 10.6 45.7 65.5 34.3 49.7 19.3 26.8 34.1 47.1 24.1 35.3 30.1 100.6 60.2 103.5 27.5 38.9 39.5 22.2 68.8 47.7 66.5 31.2 68.3 57.7 57.1 113.1 46.6 150.8 35.2 27.0 49.5 48.6 37.6 27.9 44.5 48.1 146.8 34.6 50.0 121.7 78.5 115.4 59.5 78.4 68.7 58.0 57.2 41.2 55.3 79.3 51.2 55.7 26.3 80.6 46.2 29.5 25.1 48.4 39.3 38.5 51.1 27.2 61.4 42.0 70.7 132.2 26.3 69.7 43.2 7.5 4.0 2.9 6.1 6.7 6.5 8.4 5.9 6.2 6.3 7.9 6.7 6.2 0.7 7.3 6.3 6.8 6.8 2.6 10.0 10.1 9.8 13.0 10.0 10.3 10.1 10.1 10.3 9.9 10.3 10.6 25.2 3.2 17.0 4.6 29.0 57.9 40.9 42.7 27.3 11.9 36.3 37.2 13.8 14.3 33.1 16.5 14.6 69.9 23.4 18.5 25.4 49.2 1.3 54.0 39.9 30.9 18.6 62.1 6.6 53.8 65.8 24.7 30.1 36.9 19.0 38.1 18.2 19.6 35.8 5.0 6.3 40.7 10.2 13.3 17.2 4.3 22.1 16.0 17.8 5.6 16.1 39.2 17.5 5.5 7.4 49.5 22.7 18.8 24.7 68.5 14.5 40.4 35.6 9.3 6.6 35.2 27.7 45.0 38.3 40.2 60.0 87.8 24.8 44.6 46.1 40.6 GGCT "C7orf24, CRF21, GCTG, Ggc, MGC3077" ENSG00000006625 Gamma-glutamylcyclotransferase O75223 7 30496621-30504841 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 414.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020735, HPA029914" Approved NA Yes 2100000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA020735: AB_1845754, HPA029914: AB_10602321" "prognostic unfavorable (7.68e-4)" "unprognostic (2.66e-1)" "unprognostic (2.51e-2)" "unprognostic (2.62e-1)" "unprognostic (2.54e-3)" "unprognostic (5.80e-2)" "prognostic unfavorable (7.23e-4)" "unprognostic (1.33e-3)" "unprognostic (2.19e-2)" "unprognostic (6.42e-3)" "unprognostic (2.66e-3)" "unprognostic (1.68e-1)" "unprognostic (2.27e-2)" "unprognostic (1.19e-1)" "unprognostic (8.12e-3)" "unprognostic (2.00e-3)" "unprognostic (9.92e-2)" 58.6 25.6 18.1 28.4 20.5 22.4 44.8 16.9 24.4 19.2 19.5 38.6 31.3 17.3 105.2 51.7 24.4 25.9 13.0 20.0 18.3 31.9 35.6 16.6 27.8 18.0 18.1 15.5 23.3 43.5 15.9 34.8 17.3 24.9 39.4 10.7 33.4 15.9 16.9 56.5 26.6 21.2 17.3 16.0 22.7 12.1 19.7 21.9 19.3 20.8 32.2 33.1 31.2 17.8 194.0 50.0 79.4 107.7 32.6 58.8 92.5 64.6 25.1 60.5 72.4 66.6 66.1 123.7 42.0 24.3 68.9 238.8 84.1 67.8 78.6 24.0 93.1 87.7 104.6 88.6 42.6 150.1 65.4 57.6 53.4 63.4 81.0 20.9 62.1 58.7 126.8 69.4 48.6 108.6 91.4 202.1 115.6 198.3 79.5 90.1 91.9 123.8 59.5 174.0 100.3 101.2 58.0 355.9 73.5 102.8 228.7 140.7 37.7 39.6 75.6 75.6 128.6 50.8 129.2 96.7 30.9 201.4 75.9 10.4 19.9 7.0 14.1 20.4 19.9 22.7 18.8 18.4 34.2 17.2 17.8 17.4 1.1 25.0 12.2 30.0 26.1 17.2 18.1 20.5 16.9 24.4 20.0 18.3 18.0 18.1 17.3 17.3 19.7 17.8 37.9 16.0 39.4 10.1 25.1 77.0 50.1 96.0 60.3 23.4 107.0 109.5 51.6 24.3 67.0 44.1 4.2 414.7 21.8 56.9 123.3 99.8 29.2 129.6 40.4 46.3 28.3 53.0 26.0 80.1 167.7 41.4 44.9 103.8 27.3 53.5 33.5 51.4 129.8 33.7 10.1 90.1 67.1 44.5 57.4 10.0 24.8 42.8 62.2 12.2 36.2 32.2 24.7 8.5 8.9 60.1 50.6 39.1 33.4 68.8 60.6 188.4 69.4 15.1 26.3 25.2 45.1 63.3 46.7 147.0 74.7 135.6 26.7 67.7 138.0 69.6 GINS2 "Pfs2, PSF2" ENSG00000131153 "GINS complex subunit 2" Q9Y248 16 85676198-85690073 "Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 163.5;Spermatogonia: 148.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 8.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-698: 271.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA057285 Uncertain Approved Nucleoplasm No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA057285: AB_2683398" "unprognostic (3.22e-2)" "unprognostic (1.13e-3)" "unprognostic (2.04e-3)" "unprognostic (2.09e-1)" "unprognostic (2.64e-1)" "unprognostic (1.30e-1)" "unprognostic (2.45e-3)" "unprognostic (2.58e-2)" "unprognostic (1.67e-2)" "unprognostic (2.52e-3)" "unprognostic (2.19e-2)" "unprognostic (5.82e-3)" "unprognostic (5.70e-3)" "unprognostic (4.54e-2)" "unprognostic (6.30e-2)" "unprognostic (5.44e-3)" "unprognostic (1.60e-1)" 1.0 0.9 3.0 5.4 2.8 14.7 3.7 3.0 3.7 1.7 2.2 6.4 4.6 1.6 1.3 4.7 1.1 0.4 0.6 4.5 2.2 0.7 3.0 0.8 9.0 2.3 2.4 1.4 0.9 2.6 0.8 3.0 2.3 1.5 7.0 11.1 1.3 0.8 2.7 3.2 5.3 1.6 2.3 3.0 2.2 9.6 2.3 10.2 1.8 1.0 11.0 1.4 2.1 2.6 50.7 36.2 69.0 28.9 2.0 6.7 18.3 33.8 13.7 49.8 30.5 48.2 32.9 60.0 18.1 12.0 26.0 38.0 73.7 28.1 47.9 20.8 63.9 29.2 25.7 54.6 0.3 20.6 15.6 1.8 3.4 30.0 11.5 6.1 21.6 47.5 82.4 13.8 28.9 107.1 72.7 77.8 38.8 45.0 27.3 100.7 41.5 33.1 16.4 20.9 94.2 30.0 49.4 10.0 10.0 27.3 100.0 28.2 12.8 32.1 42.5 30.6 39.5 25.6 48.3 271.9 18.7 43.4 37.2 0.7 0.2 1.1 1.0 1.0 0.1 1.0 3.3 2.3 1.3 0.7 1.6 1.1 0.9 3.2 2.8 0.8 8.5 1.7 3.0 2.8 3.0 3.7 4.5 2.2 2.3 2.4 2.3 2.3 2.3 2.6 0.6 3.2 0.0 0.7 8.5 9.2 7.4 9.5 4.0 20.3 13.1 18.5 1.0 0.0 3.8 3.7 2.1 35.3 3.1 11.9 3.9 8.2 9.8 1.5 3.3 2.4 3.0 43.3 0.5 1.5 31.8 7.2 5.6 2.7 1.3 21.6 0.0 2.1 23.8 8.4 0.4 14.9 4.1 1.3 6.6 29.4 1.2 3.3 0.0 0.0 1.1 5.6 0.0 1.0 0.6 2.0 4.5 1.9 43.1 2.6 2.4 0.7 1.7 7.5 19.7 4.2 7.9 163.5 148.4 13.8 3.8 12.7 4.2 2.2 33.6 7.4 GOT1 AST1 ENSG00000120053 "Glutamic-oxaloacetic transaminase 1" P17174 10 99396870-99430624 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Amino-acid biosynthesis" "Aminotransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "heart muscle: 511.1;liver: 369.5;skeletal muscle: 489.9;tongue: 1011.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 449.0;Distal tubular cells: 240.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064532, HPA072629" Enhanced Supported Nucleoplasm,Cytosol NA Yes 100000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "HPA064532: AB_2685279, HPA072629: AB_2686540" "unprognostic (6.40e-2)" "prognostic favorable (6.23e-4)" "unprognostic (5.99e-2)" "unprognostic (2.84e-2)" "unprognostic (2.82e-1)" "unprognostic (2.96e-2)" "unprognostic (5.25e-2)" "unprognostic (1.08e-3)" "unprognostic (6.67e-2)" "unprognostic (1.45e-1)" "unprognostic (1.79e-2)" "unprognostic (1.79e-1)" "prognostic favorable (3.72e-13)" "unprognostic (1.93e-2)" "unprognostic (4.23e-1)" "unprognostic (6.85e-2)" "unprognostic (1.00e-1)" 14.7 54.9 67.8 14.7 71.1 8.0 22.7 70.3 119.1 53.1 82.6 50.9 62.0 13.1 25.9 42.7 17.9 49.0 511.1 70.0 77.6 143.1 369.5 15.5 14.1 83.5 55.0 18.1 34.0 142.4 22.5 14.4 83.7 22.7 59.2 106.2 48.6 27.4 489.9 23.9 45.8 21.4 48.4 16.9 58.9 33.6 69.1 17.7 47.7 1011.6 30.3 22.3 21.0 70.1 73.7 40.3 46.0 114.4 35.1 30.7 127.1 58.9 108.7 101.8 109.8 89.9 56.4 71.9 20.4 50.2 89.2 88.6 107.1 78.9 105.8 25.7 46.7 28.1 46.7 114.3 184.9 77.9 44.0 47.3 82.5 86.9 228.4 69.5 49.5 48.6 71.1 106.2 65.4 64.9 42.5 56.5 29.2 118.7 56.1 45.5 44.4 72.8 173.7 37.5 19.6 28.7 44.8 59.3 222.6 66.8 115.7 27.1 23.3 25.4 56.3 28.0 68.7 76.8 99.7 74.3 65.4 40.8 34.1 4.0 8.7 6.8 19.7 25.8 18.4 17.6 21.5 20.7 21.9 21.2 15.6 22.7 0.8 20.5 31.5 36.4 27.6 15.6 67.8 71.1 70.3 119.1 70.0 77.6 83.5 55.0 83.7 48.4 69.1 70.1 10.3 16.0 16.2 26.1 38.8 11.9 41.8 82.7 24.5 95.6 18.8 21.2 449.0 72.9 34.4 73.5 62.6 35.9 10.7 62.1 240.7 51.9 166.7 17.8 9.3 16.7 19.7 39.5 47.4 30.8 18.1 23.5 76.9 21.5 31.8 20.2 17.2 191.8 31.6 75.7 63.3 45.3 54.9 12.4 6.9 24.1 11.1 13.0 49.8 13.1 10.5 36.6 6.2 21.1 37.2 27.6 34.4 14.3 22.4 13.1 97.0 163.3 27.9 76.5 13.1 15.2 20.5 116.7 10.4 40.9 10.4 55.1 14.6 47.0 66.4 42.3 GPANK1 "ANKRD59, BAT4, D6S54E, G5, GPATCH10" ENSG00000204438 "G-patch domain and ankyrin repeats 1" O95872 6 31661228-31666283 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 180.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006301 Approved Approved "Endoplasmic reticulum" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum" "HPA006301: AB_1078267" "unprognostic (2.03e-1)" "unprognostic (2.84e-2)" "unprognostic (1.56e-1)" "unprognostic (1.05e-1)" "unprognostic (4.26e-2)" "unprognostic (1.20e-1)" "unprognostic (1.77e-2)" "unprognostic (5.72e-2)" "unprognostic (1.10e-1)" "unprognostic (8.81e-2)" "prognostic favorable (5.89e-4)" "unprognostic (2.29e-1)" "unprognostic (2.46e-2)" "unprognostic (2.00e-1)" "unprognostic (1.86e-1)" "unprognostic (5.40e-2)" "unprognostic (1.51e-1)" 14.5 11.8 1.5 2.7 1.9 3.9 14.7 3.6 2.8 14.9 1.4 15.9 1.6 15.9 2.5 11.4 14.9 2.1 21.5 1.5 1.8 14.7 16.0 13.2 3.8 2.0 1.7 17.3 15.1 3.3 13.5 1.8 2.2 14.0 2.4 2.3 13.8 2.0 28.4 15.8 15.6 1.1 1.4 16.7 15.4 36.4 1.8 6.7 12.8 2.8 2.3 15.0 13.3 2.6 3.3 3.3 1.7 5.6 8.3 6.6 4.4 3.2 5.2 3.1 4.2 0.2 4.8 10.8 5.2 3.4 4.2 3.9 0.0 8.1 2.3 6.4 5.6 11.3 0.0 3.7 5.7 3.7 4.3 3.2 4.3 10.4 6.9 6.1 3.8 10.9 3.0 8.8 4.2 2.6 13.1 4.4 0.0 5.1 1.2 5.4 7.5 7.9 5.1 2.6 12.6 8.4 4.3 1.9 5.4 4.6 5.1 9.2 4.8 7.3 7.0 0.5 0.0 6.5 10.8 4.1 8.6 7.9 4.2 11.8 3.1 9.9 4.1 2.5 4.1 2.0 3.2 2.5 3.1 2.9 3.7 3.3 9.5 4.5 2.6 3.8 4.6 2.7 1.5 1.9 3.6 2.8 1.5 1.8 2.0 1.7 2.2 1.4 1.8 2.6 22.6 38.5 21.7 5.9 30.5 25.0 24.2 27.6 23.3 29.1 25.0 23.4 35.9 30.0 21.6 18.4 35.5 30.1 28.3 26.4 45.0 31.6 55.4 21.9 21.4 29.1 27.1 33.0 3.2 23.6 39.7 23.8 13.3 22.9 35.4 21.9 27.8 30.3 27.7 11.8 3.5 29.9 22.4 27.0 18.5 51.5 34.5 21.0 19.6 3.7 43.5 37.8 47.4 5.0 7.3 21.9 43.3 24.8 29.2 32.3 90.5 74.5 20.1 47.3 19.7 21.6 29.7 180.8 87.2 16.2 34.2 47.1 26.9 17.3 26.9 19.9 GPRC5A "PEIG-1, RAI3, RAIG1, TIG1" ENSG00000013588 "G protein-coupled receptor class C group 5 member A" Q8NFJ5 12 12891559-12917937 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 201.9;urinary bladder: 130.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 939.1;Club cells: 357.8;Distal enterocytes: 477.9;Pancreatic endocrine cells: 600.7;Paneth cells: 359.8;Urothelial cells: 1252.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 355.6;A549: 285.7;CAPAN-2: 1347.4;HaCaT: 351.2;SiHa: 492.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA007928, HPA046526" Enhanced Enhanced "Vesicles,Plasma membrane" NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Plasma membrane" "HPA007928: AB_1849318, HPA046526: AB_2679685" "unprognostic (4.79e-2)" "unprognostic (8.35e-2)" "unprognostic (4.21e-2)" "unprognostic (1.64e-1)" "unprognostic (4.65e-3)" "unprognostic (1.73e-1)" "unprognostic (2.38e-2)" "unprognostic (1.89e-2)" "unprognostic (3.48e-1)" "unprognostic (8.69e-3)" "prognostic unfavorable (4.63e-6)" "unprognostic (3.81e-1)" "prognostic unfavorable (9.02e-5)" "unprognostic (9.30e-2)" "unprognostic (4.34e-1)" "unprognostic (1.62e-2)" "unprognostic (2.49e-1)" 31.5 3.7 1.2 11.5 0.9 1.8 9.6 1.0 1.4 35.4 3.4 56.4 18.7 8.9 0.4 23.0 9.8 24.9 18.9 1.8 0.8 9.0 1.8 201.9 0.2 2.7 4.5 21.4 2.7 0.9 2.5 13.5 1.0 10.2 48.4 1.6 23.5 1.3 0.7 5.8 20.9 5.1 0.5 0.4 33.6 1.5 2.1 0.3 55.5 0.6 4.4 130.8 30.6 1.8 355.6 285.7 0.1 1.3 3.4 1.5 18.4 105.2 39.5 66.2 49.4 49.1 1347.4 0.1 8.6 83.3 67.2 351.2 1.0 50.1 101.7 0.4 4.3 0.2 105.4 2.2 23.8 0.1 0.3 1.8 66.5 27.5 6.7 82.3 40.9 0.0 0.5 0.3 2.9 251.7 0.2 0.3 1.6 130.0 43.5 0.2 6.7 0.3 133.6 69.6 0.5 0.6 492.0 36.8 15.9 52.3 10.9 1.0 4.0 2.6 83.9 156.1 4.3 0.2 0.3 0.3 34.6 0.3 2.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 1.2 0.9 1.0 1.4 1.8 0.8 2.7 4.5 1.0 0.5 2.1 1.8 10.0 939.1 200.2 0.0 1.0 12.5 329.6 202.8 4.6 0.1 80.6 41.7 1.9 11.5 357.8 46.0 0.0 3.8 1.5 477.9 0.0 46.9 0.1 91.8 54.1 15.8 8.3 0.0 0.2 72.1 11.7 108.5 176.9 288.1 10.1 0.2 8.6 0.2 1.6 0.0 0.4 43.5 61.1 0.3 18.0 0.4 13.4 9.6 51.6 0.0 0.6 3.5 0.0 0.0 0.1 600.7 359.8 10.1 0.5 320.1 114.0 0.2 86.3 0.4 0.0 23.0 38.8 1.5 0.3 22.7 9.1 1.1 4.9 0.7 110.4 1252.7 GPRC5C RAIG-3 ENSG00000170412 "G protein-coupled receptor class C group 5 member C" Q9NQ84 17 74424851-74451653 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 192.7;stomach 1: 230.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 211.3;Gastric mucus-secreting cells: 143.2;Hepatocytes: 183.6;Paneth cells: 153.8;Sertoli cells: 144.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 7.9" "Group enriched" "Detected in many" 9 "dendritic cells: 7.9;monocytes: 3.7" "Cell line enhanced" "Detected in many" "Hep G2: 82.4;HMC-1: 146.7;PC-3: 80.8;RPTEC TERT1: 172.1;RT4: 89.9;T-47d: 108.0" "Region enriched" "Detected in all" 9 "cerebellum: 42.5" "Low region specificity" "Detected in all" HPA029776 Enhanced Uncertain "Nucleoplasm,Centriolar satellite,Cytosol" NA Yes 15000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" "Centriolar satellite" "Nucleoplasm, Cytosol" "HPA029776: AB_10602324" "unprognostic (1.48e-1)" "unprognostic (3.35e-1)" "unprognostic (6.01e-2)" "unprognostic (2.37e-3)" "unprognostic (1.80e-2)" "unprognostic (1.09e-2)" "unprognostic (4.40e-2)" "unprognostic (1.57e-1)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" "unprognostic (9.61e-3)" "unprognostic (1.05e-1)" "prognostic favorable (1.58e-5)" "unprognostic (7.58e-2)" "unprognostic (3.70e-2)" "unprognostic (2.75e-2)" "unprognostic (1.54e-3)" 16.1 19.3 17.4 3.1 18.4 0.4 20.1 48.9 18.1 42.0 28.0 38.7 25.0 17.1 10.2 12.2 30.0 21.3 33.7 14.8 16.9 135.7 192.7 23.0 2.1 18.1 18.7 38.2 136.1 28.2 14.8 11.9 18.6 45.6 14.6 1.5 37.4 24.3 110.1 43.9 30.3 4.0 16.6 22.3 230.3 4.0 17.0 4.4 74.8 33.9 3.0 30.8 20.9 15.7 17.3 61.6 3.8 5.5 0.0 0.0 0.2 0.3 0.0 0.0 0.0 66.4 73.0 0.0 45.0 0.3 18.5 52.9 7.7 1.0 0.1 0.2 10.7 0.0 4.0 82.4 15.8 0.0 146.7 1.3 26.7 0.0 0.0 69.2 0.0 0.1 4.8 1.2 0.0 18.0 0.7 17.2 9.2 79.5 80.8 0.2 0.1 2.8 172.1 89.9 27.5 2.5 3.7 5.9 0.1 33.1 108.0 4.6 0.0 0.0 5.5 0.1 0.1 0.1 0.4 0.2 6.5 2.5 0.4 0.0 1.1 0.1 0.0 2.5 0.0 0.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 3.7 7.9 0.0 0.3 17.4 18.4 48.9 18.1 14.8 16.9 18.1 18.7 18.6 16.6 17.0 15.7 11.2 3.2 57.7 13.4 1.4 13.6 39.2 79.6 26.7 0.8 27.3 19.4 211.3 67.2 76.2 136.1 0.0 0.8 11.8 74.9 29.4 65.5 0.1 62.5 6.6 20.9 45.5 5.3 0.1 68.1 20.3 11.3 143.2 74.9 10.2 0.1 48.2 183.6 12.3 5.0 0.5 50.8 69.2 16.3 4.6 1.7 18.0 6.3 3.6 2.8 4.1 15.9 0.0 5.0 0.2 41.2 153.8 22.2 1.2 44.6 61.0 73.5 45.4 1.5 144.7 4.7 64.0 0.5 5.0 14.8 11.2 25.3 2.4 1.5 48.5 63.1 GRINA "HNRGW, LFG1, NMDARA1, TMBIM3" ENSG00000178719 "Glutamate ionotropic receptor NMDA type subunit associated protein 1" Q7Z429 8 143990056-143993415 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 432.6;monocytes: 355.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036980, HPA036981" Approved Approved "Nucleoli fibrillar center,Cytosol" NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 3: Monocytes - Immune response regulation" "Nucleoli fibrillar center" Cytosol "HPA036980: AB_10696791, HPA036981: AB_10962980" "unprognostic (2.73e-3)" "unprognostic (2.18e-3)" "unprognostic (1.79e-2)" "unprognostic (1.12e-1)" "unprognostic (7.01e-3)" "unprognostic (3.72e-2)" "unprognostic (1.69e-1)" "unprognostic (1.35e-2)" "unprognostic (2.32e-1)" "unprognostic (6.70e-2)" "unprognostic (8.19e-2)" "unprognostic (3.13e-3)" "unprognostic (1.01e-3)" "unprognostic (1.55e-1)" "unprognostic (9.43e-2)" "unprognostic (6.75e-2)" "unprognostic (5.72e-2)" 273.1 218.3 154.1 109.0 147.4 215.1 236.4 143.9 226.4 178.9 99.4 144.9 72.1 137.8 79.7 134.2 149.0 74.5 154.8 158.9 149.8 200.8 447.1 233.9 77.7 151.6 155.6 152.7 97.2 144.4 127.7 86.2 160.5 176.0 33.2 180.7 116.7 181.7 145.4 167.1 138.1 75.1 152.1 311.3 104.6 269.4 163.1 58.5 187.4 57.4 55.2 162.1 139.3 140.2 79.3 155.9 76.4 129.5 392.6 196.9 114.5 112.5 258.9 184.4 168.7 95.5 64.3 57.9 120.2 249.7 128.6 69.8 136.8 162.3 75.5 83.1 95.9 60.2 85.9 114.5 412.0 12.7 90.7 254.2 441.0 132.7 193.3 194.5 90.1 23.9 56.1 76.8 160.7 489.5 34.7 32.6 53.4 75.8 231.2 45.4 39.9 111.4 93.2 229.1 52.3 84.8 163.5 177.9 225.8 104.1 342.2 77.6 91.8 115.4 127.1 158.0 82.1 124.3 78.3 44.6 147.4 79.0 67.6 1.8 32.0 9.7 2.5 36.4 3.5 8.3 2.5 2.9 13.3 7.1 4.5 4.1 18.6 3.3 36.1 22.9 2.3 16.0 154.1 147.4 143.9 226.4 158.9 149.8 151.6 155.6 160.5 152.1 163.1 140.2 54.5 19.2 52.7 35.3 45.4 37.2 32.5 58.7 121.3 91.1 62.7 79.4 23.2 45.8 27.9 53.3 79.2 137.2 22.6 29.1 23.5 75.0 273.8 36.8 56.1 47.7 42.1 60.0 21.3 69.1 55.8 67.7 16.8 36.1 16.4 76.2 51.4 194.5 178.4 33.7 26.6 24.3 42.7 225.1 86.7 432.6 61.5 184.3 37.4 22.5 355.1 89.9 6.2 12.5 9.3 66.0 54.5 67.7 44.4 46.7 72.9 73.6 29.4 95.8 46.0 32.4 45.6 96.0 16.9 83.2 36.9 264.2 20.8 38.7 31.4 25.5 H2AC11 "H2A.1b, H2A/p, H2AFP, HIST1H2AG, pH2A/f" ENSG00000196787 "H2A clustered histone 11" P0C0S8 6 27133042-27135291 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 2.8;testis: 3.1" "Group enriched" "Detected in some" 10 "Cardiomyocytes: 1.2;Cytotrophoblasts: 2.0;dendritic cells: 1.5;Extravillous trophoblasts: 3.1;Hofbauer cells: 2.6;Plasma cells: 1.3;Syncytiotrophoblasts: 3.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 9.5" "Group enriched" "Detected in many" 5 "B-cells: 2.8;granulocytes: 9.5;T-cells: 2.9" "Cell line enhanced" "Detected in many" "K-562: 15.5;SiHa: 17.3;U-266/84: 48.8" "Low region specificity" "Detected in many" HPA041189 Supported Approved Nucleoplasm NA Yes "Cluster 38: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 16: U-266 - Nucleosome" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA041189: AB_2677357" "unprognostic (4.86e-2)" "unprognostic (6.89e-2)" "unprognostic (1.66e-1)" "unprognostic (3.94e-1)" "unprognostic (8.67e-2)" "unprognostic (1.03e-3)" "unprognostic (1.95e-1)" "unprognostic (5.78e-2)" "unprognostic (2.41e-1)" "unprognostic (2.37e-1)" "unprognostic (2.14e-3)" "unprognostic (1.53e-2)" "unprognostic (7.36e-2)" "unprognostic (5.98e-2)" "unprognostic (6.48e-2)" "unprognostic (8.22e-3)" "unprognostic (9.54e-2)" 0.3 0.3 0.7 0.3 0.9 2.4 2.8 0.5 0.7 0.5 0.7 0.9 1.3 0.1 0.6 0.6 0.2 0.3 0.2 0.6 1.0 0.2 0.5 0.3 1.0 1.5 1.4 0.1 0.2 0.0 0.1 0.4 1.4 0.7 0.7 0.1 0.1 0.4 0.2 0.2 1.1 0.2 1.2 0.9 0.5 3.1 1.7 1.9 0.3 0.3 0.4 0.4 0.4 1.7 2.1 2.8 2.3 2.0 7.1 1.5 1.5 0.7 1.1 2.4 0.3 1.2 2.1 0.7 3.0 0.9 2.3 4.2 2.8 1.2 1.6 3.7 1.6 1.1 5.2 0.0 1.5 1.1 2.2 2.7 0.5 0.7 0.8 1.2 0.8 2.0 15.5 6.9 0.1 2.7 2.9 1.8 1.3 3.1 1.9 1.9 2.3 8.0 0.4 0.5 9.0 2.1 17.3 2.7 1.0 1.1 0.0 0.7 0.9 2.6 5.8 2.1 1.1 12.4 48.8 4.9 0.5 1.7 1.6 9.5 0.3 0.6 0.4 0.2 0.9 2.3 1.7 1.1 0.5 2.8 1.4 1.3 2.3 0.9 0.6 1.0 2.9 5.3 0.7 0.9 0.5 0.7 0.6 1.0 1.5 1.4 1.4 1.2 1.7 1.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 2.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.0 0.2 0.0 0.0 0.0 H2AC20 "H2A, H2A/q, H2AFQ, HIST2H2AC" ENSG00000184260 "H2A clustered histone 20" Q16777 1 149886918-149887411 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 25.3;brain: 27.2;choroid plexus: 20.0" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 5.7;dendritic cells: 8.1;Extravillous trophoblasts: 18.2;Hofbauer cells: 9.7;Syncytiotrophoblasts: 8.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 60.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041189 Supported Approved Nucleoplasm NA Yes "Cluster 1: Neutrophils - Mixed function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA041189: AB_2677357" "unprognostic (5.50e-3)" "unprognostic (4.97e-2)" "unprognostic (9.34e-2)" "unprognostic (6.95e-2)" "unprognostic (1.49e-1)" "unprognostic (9.78e-3)" "unprognostic (1.01e-1)" "unprognostic (2.25e-1)" "unprognostic (1.81e-1)" "unprognostic (3.24e-2)" "unprognostic (4.25e-2)" "unprognostic (7.87e-2)" "prognostic unfavorable (1.20e-10)" "unprognostic (1.42e-1)" "unprognostic (1.73e-1)" "unprognostic (4.89e-2)" "prognostic favorable (7.86e-5)" 3.8 3.6 15.5 0.8 20.6 25.3 3.5 24.0 14.0 5.4 20.0 3.1 0.2 2.0 0.0 2.2 2.7 0.4 2.6 10.0 27.2 2.3 2.6 4.7 0.5 19.8 13.1 4.3 2.4 0.1 3.0 0.5 16.7 3.2 0.1 0.5 1.4 0.1 0.7 4.5 3.3 0.4 19.9 5.2 2.5 1.2 18.2 1.6 1.8 0.0 0.1 2.5 4.1 18.2 3.9 4.2 5.0 15.7 0.0 0.7 7.8 1.2 0.9 2.4 3.3 2.5 1.1 8.0 0.2 0.2 0.5 2.0 0.3 1.6 0.0 0.7 5.7 1.9 1.6 12.2 0.0 4.7 4.6 0.9 0.2 0.2 0.5 0.1 1.6 2.0 1.7 10.0 0.5 60.6 5.7 5.4 6.7 4.5 10.0 1.8 2.2 1.4 1.0 2.4 1.8 7.5 3.2 1.2 3.8 0.4 0.6 4.4 1.5 1.1 10.9 1.9 2.9 5.5 4.0 4.2 2.9 6.3 2.3 47.2 33.8 19.0 22.9 22.6 20.2 13.1 20.1 18.5 17.7 33.1 14.0 14.8 98.4 19.1 25.6 24.9 16.3 22.6 15.5 20.6 24.0 14.0 10.0 27.2 19.8 13.1 16.7 19.9 18.2 18.2 2.4 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 5.7 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 18.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 8.8 1.5 0.0 0.0 0.0 H2AC7 "H2A.3, H2A/g, H2AFG, HIST1H2AD" ENSG00000196866 "H2A clustered histone 7" P20671 6 26198784-26199293 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 17.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 17.5;U-266/84: 6.3" "Low region specificity" "Detected in all" HPA041189 Supported Approved Nucleoplasm NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 29: U-266 - Adaptive immune response" Nucleoplasm "HPA041189: AB_2677357" "unprognostic (5.03e-2)" "unprognostic (1.11e-2)" "unprognostic (7.27e-2)" "unprognostic (3.56e-1)" "unprognostic (9.17e-2)" "unprognostic (1.45e-1)" "unprognostic (9.09e-3)" "unprognostic (6.72e-2)" "unprognostic (1.92e-1)" "unprognostic (4.34e-1)" "unprognostic (1.81e-1)" "unprognostic (2.88e-2)" "unprognostic (1.10e-9)" "unprognostic (2.00e-1)" "unprognostic (1.34e-1)" "unprognostic (3.27e-1)" "unprognostic (2.14e-2)" 0.7 0.2 0.4 0.3 1.7 2.9 0.6 4.1 2.1 3.3 3.6 0.5 0.0 0.1 0.0 2.5 0.6 0.3 0.4 1.0 1.9 0.6 1.2 2.1 0.5 3.1 1.7 0.7 0.1 0.0 0.3 0.2 2.1 2.1 0.1 0.0 0.5 0.0 0.0 1.1 0.5 0.0 3.9 1.2 0.6 0.3 3.0 1.8 0.3 0.0 0.3 0.3 2.8 6.8 1.1 0.0 0.2 0.2 0.0 0.0 0.2 0.7 0.1 1.1 0.0 1.3 0.4 0.7 1.2 0.2 0.1 0.3 0.0 0.1 0.2 0.0 1.0 0.3 1.4 1.3 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.1 0.0 0.7 2.5 1.3 0.0 0.0 3.7 1.5 1.1 0.0 1.1 1.0 0.4 0.9 0.4 0.1 1.4 0.2 0.6 0.8 0.1 0.0 1.4 0.3 0.0 1.1 3.1 0.0 1.0 17.5 6.3 2.2 1.0 1.3 0.4 2.3 0.3 3.8 1.3 1.9 1.3 2.7 2.0 4.0 1.1 7.6 1.9 1.9 17.9 1.8 2.2 6.2 2.7 0.8 0.4 1.7 4.1 2.1 1.0 1.9 3.1 1.7 2.1 3.9 3.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 H2AX H2AFX ENSG00000188486 "H2A.X variant histone" P16104 11 119093854-119095467 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair, Host-virus interaction, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 43.7;Cytotrophoblasts: 83.2;dendritic cells: 34.0;Extravillous trophoblasts: 106.6;Hofbauer cells: 45.8;Syncytiotrophoblasts: 64.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012264, HPA041189, HPA051647" Supported Supported "Nucleoplasm,Nuclear speckles" Yes Yes "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Nuclear speckles" "CAB012264: AB_297215, HPA041189: AB_2677357, HPA051647: AB_2681563" "unprognostic (1.44e-1)" "unprognostic (1.96e-1)" "unprognostic (6.46e-2)" "unprognostic (6.41e-2)" "unprognostic (3.07e-1)" "unprognostic (3.25e-1)" "prognostic unfavorable (1.51e-4)" "unprognostic (2.32e-3)" "unprognostic (1.93e-1)" "unprognostic (3.07e-3)" "unprognostic (6.78e-2)" "unprognostic (9.31e-2)" "prognostic unfavorable (5.47e-9)" "unprognostic (1.21e-3)" "unprognostic (1.20e-1)" "unprognostic (1.20e-1)" "unprognostic (1.99e-2)" 13.2 20.7 35.2 12.6 37.8 24.9 8.0 39.0 42.2 13.3 20.6 18.6 13.3 14.0 2.1 43.6 13.1 3.1 13.4 33.7 32.3 17.0 13.9 14.3 16.0 43.9 38.9 18.7 11.6 3.4 24.3 11.0 37.8 15.7 4.3 6.6 11.4 4.7 12.4 18.1 18.8 3.5 38.0 24.0 16.1 15.4 37.8 30.5 10.4 3.6 12.0 11.8 15.7 51.8 132.1 77.9 120.3 72.3 10.9 7.9 126.4 146.0 44.0 80.3 70.4 124.0 55.1 89.7 85.9 34.0 60.5 134.0 57.5 41.7 21.5 133.4 161.0 182.2 20.7 129.8 11.4 90.5 108.9 6.7 9.0 34.2 21.0 13.1 40.7 115.4 149.9 143.1 38.9 335.6 207.8 269.9 87.5 60.0 162.6 200.7 141.6 42.7 37.5 56.3 127.6 152.0 116.0 66.6 20.6 20.6 99.8 68.2 50.9 77.7 204.2 63.8 110.2 38.7 40.8 92.3 17.9 145.2 155.0 3.8 1.3 4.2 1.6 0.6 0.8 0.9 1.7 1.7 1.8 0.8 1.1 1.0 0.6 2.2 0.8 0.8 1.6 1.2 35.2 37.8 39.0 42.2 33.7 32.3 43.9 38.9 37.8 38.0 37.8 51.8 43.7 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.0 0.0 0.0 83.2 34.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 106.6 9.4 0.0 0.0 0.0 0.0 0.0 0.0 45.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 64.2 7.2 0.0 0.0 0.0 H2BC21 "H2B, H2B.1, H2B/q, H2BE, H2BFQ, HIST2H2BE" ENSG00000184678 "H2B clustered histone 21" Q16778 1 149884459-149886652 "Predicted intracellular proteins" "Antibiotic, Antimicrobial, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 86.5;Syncytiotrophoblasts: 160.2" "Cancer enhanced" "Detected in all" "prostate cancer: 87.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 58.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 58.6" "Cell line enhanced" "Detected in many" "Karpas-707: 56.8;U-266/70: 93.7;U-266/84: 53.8" "Low region specificity" "Detected in all" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA Yes "Cluster 50: Neutrophils - Cellular senescence" "Cluster 27: Brain & Skin - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm Cytosol "HPA042205: AB_2677900, HPA043013: AB_2678269, HPA048671: AB_2680488" "unprognostic (1.49e-1)" "unprognostic (3.10e-2)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.63e-1)" "unprognostic (1.89e-1)" "unprognostic (2.52e-1)" "unprognostic (1.37e-1)" "unprognostic (8.28e-2)" "unprognostic (4.65e-2)" "unprognostic (3.27e-1)" "unprognostic (1.91e-1)" "unprognostic (1.30e-1)" "unprognostic (4.74e-2)" "unprognostic (4.41e-2)" "unprognostic (7.82e-2)" "unprognostic (2.20e-1)" "unprognostic (2.86e-3)" 17.8 15.3 35.1 7.2 40.2 21.2 17.7 38.7 38.7 60.8 38.7 22.0 5.2 7.4 22.8 41.7 27.5 5.5 77.3 33.5 37.2 46.3 18.0 37.2 6.2 41.6 38.0 61.7 13.4 9.5 32.5 14.8 39.0 95.2 6.1 69.1 23.5 6.6 62.8 84.0 14.8 6.2 41.0 27.3 32.0 13.7 38.9 20.1 15.2 29.2 3.4 25.1 79.5 55.8 2.8 2.8 4.5 0.9 23.5 6.3 2.2 9.7 6.5 4.0 1.3 1.1 4.4 0.5 2.6 8.6 5.7 10.9 3.6 1.7 2.2 3.4 2.8 0.8 11.5 2.1 7.4 0.8 12.6 21.4 7.9 1.7 6.6 4.8 1.3 4.0 12.0 56.8 5.0 16.8 3.1 5.1 2.8 22.6 5.8 3.6 1.7 13.7 3.8 2.3 30.3 4.9 33.4 4.5 2.7 10.7 23.4 2.4 1.7 3.0 33.6 2.2 0.9 93.7 53.8 2.6 4.0 3.6 1.9 21.3 4.8 8.2 1.3 6.2 2.3 1.5 1.8 2.1 3.3 3.8 2.2 2.2 58.6 1.3 12.3 8.9 2.2 10.1 35.1 40.2 38.7 38.7 33.5 37.2 41.6 38.0 39.0 41.0 38.9 55.8 1.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 86.5 0.0 0.0 0.0 0.0 25.5 2.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 20.2 4.6 0.0 0.0 0.0 0.0 0.0 0.0 27.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 160.2 0.3 0.0 0.0 0.0 H2BC5 "H2B/b, H2BFB, HIST1H2BD" ENSG00000158373 "H2B clustered histone 5" P58876 6 26158146-26171349 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 151.7" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 22.4;Syncytiotrophoblasts: 39.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 117.9;U-266/84: 134.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042205, HPA043013, HPA048671, CAB062336" Supported Approved Nucleoplasm,Cytosol NA Yes "Cluster 6: Non-specific - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm Cytosol "CAB062336: AB_10622324, HPA042205: AB_2677900, HPA043013: AB_2678269, HPA048671: AB_2680488" "unprognostic (2.39e-2)" "unprognostic (1.58e-2)" "prognostic unfavorable (3.84e-4)" "unprognostic (1.32e-1)" "unprognostic (1.98e-1)" "unprognostic (2.83e-2)" "unprognostic (1.54e-1)" "unprognostic (8.10e-2)" "unprognostic (2.28e-1)" "unprognostic (3.54e-2)" "unprognostic (3.68e-3)" "unprognostic (2.17e-1)" "unprognostic (4.74e-3)" "unprognostic (1.08e-1)" "unprognostic (1.56e-1)" "unprognostic (3.91e-2)" "unprognostic (1.34e-2)" 25.4 13.4 17.8 7.6 21.9 53.8 18.5 48.7 19.2 151.7 41.8 34.6 11.0 6.3 27.7 37.6 53.5 15.3 31.4 17.9 29.7 67.2 62.9 36.8 9.2 22.2 23.7 101.8 15.7 2.1 30.5 9.3 28.0 144.0 17.1 9.7 28.9 3.6 18.5 44.1 23.3 4.3 27.5 35.4 26.1 11.3 23.8 35.2 25.2 7.3 4.1 17.9 95.5 33.9 17.9 39.7 12.0 6.8 91.2 8.3 3.6 15.5 8.9 19.6 12.3 13.3 14.5 8.1 95.2 18.5 21.8 27.9 6.8 6.6 9.2 36.6 16.9 5.4 33.7 14.5 9.8 7.2 14.7 59.7 10.3 5.5 7.7 7.6 4.9 7.5 57.1 43.3 3.6 64.2 16.4 18.1 12.6 76.1 18.2 6.5 7.6 54.4 18.7 12.8 38.1 16.1 96.8 25.1 15.9 23.1 63.4 2.6 3.0 24.4 63.4 9.9 3.3 117.9 134.9 20.5 3.1 33.2 5.0 35.3 2.3 16.9 8.1 5.1 10.4 13.4 12.3 13.5 5.6 20.0 11.4 8.7 24.8 10.5 6.9 19.3 8.9 2.4 17.8 21.9 48.7 19.2 17.9 29.7 22.2 23.7 28.0 27.5 23.8 33.9 1.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.4 0.0 0.0 0.0 0.0 7.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 7.5 1.5 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 39.4 0.3 0.0 0.0 0.0 H3-3B "H3.3B, H3F3B" ENSG00000132475 "H3.3 histone B" P84243 17 75776434-75785893 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 4220.9" "Cell type enhanced" "Detected in some" "Adipocytes: 1321.3;Cytotrophoblasts: 1625.3;dendritic cells: 844.9;Extravillous trophoblasts: 1626.9;Hofbauer cells: 1908.9;Syncytiotrophoblasts: 3503.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 21089.7" "Lineage enriched" "Detected in all" 6 "granulocytes: 21089.7" "Low cell line specificity" "Detected in all" "CAB037166, CAB037187, CAB037221, HPA042570" Supported Enhanced Nucleoplasm NA Yes "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB037166: AB_2115285, CAB037187: AB_477069, CAB037221: AB_477076, HPA042570: AB_2678056" "unprognostic (1.66e-1)" "unprognostic (8.42e-3)" "unprognostic (3.42e-2)" "unprognostic (1.06e-1)" "unprognostic (1.81e-1)" "unprognostic (1.95e-1)" "unprognostic (2.41e-1)" "unprognostic (2.43e-3)" "unprognostic (3.37e-2)" "unprognostic (1.64e-1)" "unprognostic (5.88e-2)" "unprognostic (1.07e-1)" "unprognostic (1.26e-3)" "unprognostic (9.20e-2)" "unprognostic (4.81e-2)" "unprognostic (2.33e-1)" "unprognostic (1.99e-1)" 607.2 369.9 223.8 532.5 262.6 4220.9 628.9 264.4 288.8 741.2 186.6 415.4 329.9 507.4 180.3 798.6 585.7 467.9 312.8 210.7 226.0 438.3 380.2 553.2 509.1 268.7 241.9 1166.0 578.0 341.1 357.5 427.1 242.8 348.2 223.1 299.8 519.2 237.1 332.5 1153.2 407.5 322.9 253.7 449.9 393.0 654.3 246.0 464.0 500.7 155.6 296.2 545.3 675.2 316.1 1386.5 1194.2 490.0 486.1 273.3 424.9 675.1 636.7 557.1 764.8 609.3 1290.7 952.6 683.6 593.1 373.2 539.5 530.0 390.5 881.0 432.0 375.9 883.0 612.8 668.2 1112.0 615.7 1029.2 755.0 467.3 534.2 785.6 1004.7 339.3 582.5 437.8 885.6 1193.0 399.4 2015.3 1492.3 859.5 394.8 442.8 1322.8 1091.7 894.2 746.6 607.3 803.5 988.1 1096.0 645.8 933.7 1402.2 259.3 734.2 1091.3 549.1 1359.7 1205.2 595.2 1721.1 1431.3 932.2 843.5 720.5 967.6 761.1 7991.0 3667.6 10060.5 2613.4 3365.8 2482.2 3199.5 2474.2 2478.9 3218.1 2813.7 2635.4 2173.4 21089.7 3240.7 3199.0 3294.6 2999.0 9615.0 223.8 262.6 264.4 288.8 210.7 226.0 268.7 241.9 242.8 253.7 246.0 316.1 1321.3 0.0 0.0 0.0 294.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 398.6 0.0 0.0 0.0 0.0 1625.3 844.9 0.0 0.0 0.0 0.0 0.0 0.0 172.3 0.0 0.0 0.0 0.0 1626.9 485.1 0.0 0.0 0.0 0.0 0.0 0.0 1908.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 257.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 314.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 377.9 0.0 0.0 0.0 0.0 3503.3 211.7 0.0 0.0 0.0 H3C10 "H3/k, H3F1K, H3FK, HIST1H3H" ENSG00000278828 "H3 clustered histone 10" P68431 6 27810064-27811300 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 6.4" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 4.4;Extravillous trophoblasts: 3.1;Hofbauer cells: 2.3;Syncytiotrophoblasts: 5.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 8 "basophil: 101.9;neutrophil: 37.8" "Lineage enriched" "Detected in all" 12 "granulocytes: 101.9" "Cell line enhanced" "Detected in many" "K-562: 33.7;SiHa: 28.3;U-266/70: 23.5;U-266/84: 61.3" HPA042570 Approved NA Yes "Cluster 34: Basophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 24: Non-specific - Transcription regulation" "HPA042570: AB_2678056" "unprognostic (1.61e-1)" "prognostic favorable (4.35e-4)" "unprognostic (1.79e-1)" "unprognostic (1.63e-2)" "unprognostic (3.68e-2)" "unprognostic (2.27e-1)" "unprognostic (1.29e-1)" "unprognostic (3.01e-1)" "unprognostic (2.12e-1)" "unprognostic (2.93e-1)" "prognostic unfavorable (9.25e-6)" "unprognostic (1.09e-1)" "prognostic unfavorable (5.73e-5)" "unprognostic (4.09e-1)" "unprognostic (4.94e-1)" "unprognostic (3.70e-1)" "unprognostic (2.82e-2)" 1.6 1.3 0.9 0.4 0.8 4.4 0.8 0.8 1.1 2.1 1.9 2.8 1.3 0.3 0.5 3.3 0.8 0.4 1.0 1.0 0.7 1.1 2.4 4.0 1.0 1.2 1.1 1.9 0.2 0.8 0.4 0.9 1.0 2.6 2.6 0.1 0.6 0.2 0.6 1.3 1.3 0.2 1.0 6.4 1.5 1.4 1.0 3.1 1.2 1.1 0.4 0.6 2.9 1.8 1.9 7.2 3.0 2.5 4.2 0.5 0.4 1.0 0.7 3.4 1.3 2.2 2.1 1.3 6.5 0.8 2.0 3.9 1.1 1.7 2.2 9.2 4.4 1.8 6.9 9.3 1.1 1.6 2.7 5.6 0.5 0.7 0.8 1.5 1.4 1.7 33.7 15.5 0.7 14.5 3.0 3.6 1.5 13.3 2.7 1.6 0.0 17.0 3.6 0.8 9.3 1.8 28.3 5.7 1.2 1.6 13.4 0.5 1.6 1.5 4.5 0.9 0.4 23.5 61.3 5.0 0.1 7.9 0.3 101.9 4.2 9.2 1.4 1.3 1.7 1.4 2.2 2.0 3.3 5.3 1.4 1.1 37.8 1.7 1.5 7.1 8.1 203.1 0.9 0.8 0.8 1.1 1.0 0.7 1.2 1.1 1.0 1.0 1.0 1.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 4.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.2 0.3 0.0 0.0 0.0 H4C15 "H4/o, HIST2H4B" ENSG00000270276 "H4 clustered histone 15" P62805 1 149854045-149861210 "Disease related genes, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "SCLC-21H: 4.8;SiHa: 7.5;U-266/70: 8.6;U-266/84: 7.6" "Low region specificity" "Detected in all" HPA042201 Supported NA Yes 25000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA042201: AB_2677898" "unprognostic (8.20e-2)" "unprognostic (2.69e-1)" "unprognostic (1.77e-1)" 2.0 3.2 2.5 0.1 2.5 2.1 1.7 2.4 3.5 2.6 1.3 4.0 1.7 2.2 2.5 1.0 2.8 0.7 2.2 2.5 1.8 2.4 1.7 1.7 1.3 1.6 1.8 1.8 1.6 2.0 4.9 0.9 1.6 3.5 1.0 3.1 1.4 1.1 2.4 2.3 1.7 2.2 2.7 2.3 2.2 0.8 1.6 4.6 2.0 1.1 0.6 2.8 1.5 2.0 0.0 0.0 0.8 0.2 0.8 0.8 0.1 1.4 2.6 0.2 0.0 0.0 0.5 0.8 1.3 0.7 0.2 0.0 0.4 0.0 0.1 1.5 0.5 0.0 3.1 0.0 0.0 0.0 0.0 2.1 0.0 0.2 0.0 1.1 1.0 1.9 0.0 4.5 0.1 3.1 0.2 0.5 0.1 0.8 0.0 1.1 0.3 0.1 0.3 0.6 4.8 2.9 7.5 0.8 0.3 0.0 1.6 0.1 1.8 0.3 1.8 0.5 0.2 8.6 7.6 1.2 0.7 0.2 1.1 1.8 1.3 1.6 1.4 2.1 2.5 1.8 1.6 1.2 1.9 4.3 1.3 2.3 5.8 1.3 1.2 2.4 2.5 3.4 2.5 2.5 2.4 3.5 2.5 1.8 1.6 1.8 1.6 2.7 1.6 2.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 HELLS "LSH, Nbla10143, PASG, SMARCA6" ENSG00000119969 "Helicase, lymphoid specific" Q9NRZ9 10 94501434-94613905 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" "Developmental protein, Helicase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.3;lymphoid tissue: 15.9" "Cell type enhanced" "Detected in many" "Spermatocytes: 182.0;Spermatogonia: 173.9" "Cancer enhanced" "Detected in all" "testis cancer: 16.1" "Region enhanced" "Detected in many" "cerebellum: 5.5" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 36.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004491, HPA063242" Enhanced Approved "Nucleoplasm,Golgi apparatus,Vesicles" No Yes "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus, Vesicles" "CAB004491: AB_627895, HPA063242: AB_2684968" "unprognostic (1.94e-1)" "prognostic favorable (1.36e-4)" "unprognostic (9.85e-2)" "unprognostic (3.38e-2)" "unprognostic (8.65e-2)" "unprognostic (4.85e-3)" "unprognostic (1.76e-5)" "unprognostic (7.59e-3)" "unprognostic (7.03e-3)" "unprognostic (6.49e-2)" "unprognostic (2.05e-2)" "unprognostic (9.45e-5)" "unprognostic (9.93e-13)" "unprognostic (2.25e-2)" "unprognostic (1.72e-1)" "unprognostic (6.24e-2)" "unprognostic (3.03e-2)" 1.1 1.2 0.8 6.4 0.3 16.3 3.0 5.5 1.2 3.2 1.3 4.3 2.9 2.9 1.4 5.9 1.7 2.0 0.7 0.4 1.3 2.5 1.8 1.7 12.4 0.8 0.8 2.6 1.2 1.4 3.0 4.1 1.0 2.1 5.1 1.1 1.9 1.0 0.3 5.3 3.9 2.2 0.9 4.3 3.7 12.8 0.9 15.9 1.1 0.2 12.6 3.6 3.2 1.5 57.7 55.4 70.6 90.1 2.9 6.4 37.4 42.9 27.8 34.4 54.6 70.3 45.5 70.0 16.7 15.5 29.1 56.3 40.9 34.9 50.7 68.5 45.5 37.3 56.3 58.0 1.7 71.2 31.6 3.6 2.0 42.1 20.0 9.4 24.0 46.0 20.7 43.5 43.1 54.9 75.2 35.6 73.4 42.3 24.1 70.3 62.1 16.3 24.2 72.2 28.4 22.8 50.3 14.5 7.8 59.0 60.9 23.1 17.2 38.4 19.4 35.4 52.4 22.3 47.6 74.5 19.0 42.8 17.9 0.3 0.7 0.0 7.0 1.5 2.4 18.8 11.4 9.4 2.3 23.2 5.2 7.7 1.0 10.2 1.0 36.8 19.7 2.3 0.8 0.3 5.5 1.2 0.4 1.3 0.8 0.8 1.0 0.9 0.9 1.5 4.7 9.6 3.9 0.0 19.7 21.5 11.5 12.6 13.1 16.4 10.0 15.0 1.0 12.8 12.6 22.0 0.0 46.3 13.2 26.2 3.9 9.0 2.0 9.3 16.4 8.1 10.8 50.5 3.3 6.2 43.4 13.0 17.9 16.3 5.7 60.6 5.7 3.6 15.1 6.7 5.4 17.8 8.2 2.2 10.3 5.3 9.0 7.3 1.8 9.4 5.7 4.3 1.0 4.5 6.6 4.7 1.8 5.7 37.5 3.7 1.7 1.6 6.3 11.4 19.7 10.5 16.4 182.0 173.9 22.9 9.9 11.1 15.7 16.5 30.9 11.7 HMMR "CD168, RHAMM" ENSG00000072571 "Hyaluronan mediated motility receptor" O75330 5 163460203-163491941 "CD markers, FDA approved drug targets, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.6;lymphoid tissue: 27.3;testis: 27.5" "Cell type enhanced" "Detected in many" "Early spermatids: 86.2;Erythroid cells: 133.3;Extravillous trophoblasts: 55.1;Late spermatids: 60.9;Spermatocytes: 100.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB002433, HPA040025, HPA043926, HPA061524" Enhanced Enhanced Microtubules,Centrosome,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules "Centrosome, Cytosol" "CAB002433: AB_564080, HPA040025: AB_2676805, HPA043926: , HPA061524: AB_2684551" "unprognostic (3.53e-3)" "unprognostic (1.01e-1)" "unprognostic (3.38e-3)" "unprognostic (8.88e-3)" "unprognostic (2.12e-1)" "prognostic unfavorable (5.52e-4)" "prognostic unfavorable (1.93e-7)" "prognostic unfavorable (1.09e-4)" "unprognostic (5.68e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (3.71e-5)" "unprognostic (1.02e-1)" "unprognostic (0.00e+0)" "unprognostic (1.65e-2)" "unprognostic (4.98e-2)" "unprognostic (2.39e-1)" "unprognostic (1.77e-2)" 0.8 0.7 0.2 10.1 0.3 20.6 2.1 0.3 0.4 1.1 0.1 6.6 7.4 0.8 0.2 4.0 0.5 0.9 0.8 0.2 0.2 0.7 1.7 0.9 18.1 0.5 0.3 0.2 0.3 0.9 0.2 6.2 0.4 0.5 8.8 0.8 0.8 0.2 1.2 4.2 6.5 2.9 0.3 2.9 3.6 27.5 0.7 27.3 0.7 0.4 17.7 2.2 1.4 0.5 77.0 47.2 94.5 50.8 5.0 9.0 70.3 71.4 34.9 88.0 78.9 96.8 145.1 127.5 66.0 22.2 118.5 86.3 112.4 69.0 148.6 116.1 34.4 76.7 32.3 48.4 1.4 68.7 67.3 2.4 4.1 82.8 64.0 14.7 50.6 85.7 73.2 101.0 93.2 28.5 72.3 38.8 81.9 51.2 51.6 78.0 126.3 63.9 34.8 20.4 78.8 43.8 106.3 32.8 38.6 45.1 97.3 54.5 32.9 63.2 52.4 50.6 97.2 53.7 96.3 102.4 41.4 104.2 61.1 0.2 0.2 0.0 0.1 0.1 0.3 0.3 0.3 0.1 0.2 0.2 0.1 0.2 0.1 0.5 0.0 0.6 1.5 0.2 0.2 0.3 0.3 0.4 0.2 0.2 0.5 0.3 0.4 0.3 0.7 0.5 0.4 0.0 1.1 1.3 6.0 2.5 1.8 4.5 2.8 0.6 3.2 3.7 2.5 4.3 3.2 0.0 0.0 37.3 2.3 5.3 0.0 0.8 86.2 3.8 3.1 3.1 1.2 133.3 0.6 0.2 55.1 4.6 11.7 5.7 0.0 21.6 5.3 3.8 22.2 0.0 0.4 7.8 6.1 8.8 2.7 60.9 2.1 7.6 0.0 0.0 2.3 0.1 1.0 0.5 1.2 0.2 0.3 0.7 22.9 1.5 1.3 2.6 2.8 1.0 6.6 0.6 3.8 100.9 23.3 14.1 1.4 4.5 5.2 1.6 15.6 3.0 HNRNPF HNRPF ENSG00000169813 "Heterogeneous nuclear ribonucleoprotein F" P52597 10 43385617-43409166 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA016884, HPA069667" Supported Enhanced Nucleoplasm NA Yes 2500000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 6: T47d - Mammary gland" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA016884: AB_1856444, HPA069667: AB_2686166" "unprognostic (9.93e-2)" "unprognostic (2.26e-2)" "unprognostic (1.81e-1)" "unprognostic (3.65e-2)" "unprognostic (6.39e-2)" "unprognostic (3.33e-2)" "prognostic unfavorable (5.85e-4)" "unprognostic (1.51e-2)" "unprognostic (6.37e-2)" "unprognostic (6.33e-3)" "unprognostic (4.89e-3)" "unprognostic (1.07e-2)" "unprognostic (1.95e-2)" "unprognostic (3.77e-3)" "unprognostic (3.35e-1)" "unprognostic (3.71e-1)" "unprognostic (2.22e-1)" 114.6 77.7 43.3 133.9 48.6 161.3 102.9 49.8 47.9 86.8 65.2 124.5 134.2 78.3 58.9 114.9 119.4 88.9 63.7 40.2 45.9 94.4 173.2 97.6 181.4 52.4 51.4 87.3 87.5 73.1 50.5 113.6 51.5 90.8 118.9 80.4 85.2 74.8 93.6 104.5 130.7 89.1 49.2 123.5 118.0 84.0 49.4 193.3 72.7 79.6 182.8 160.0 81.8 58.3 292.1 302.9 184.2 280.7 220.5 239.5 269.1 222.5 371.0 305.6 358.2 285.5 394.7 581.8 139.2 242.0 179.3 401.7 496.8 363.6 249.5 245.6 297.2 371.2 178.6 370.9 271.4 550.5 360.9 293.2 282.4 237.6 434.6 177.1 266.4 281.3 382.0 256.2 234.2 453.4 542.5 300.5 139.5 439.1 252.4 449.0 172.7 276.8 314.9 442.7 226.1 226.8 226.6 410.4 344.3 199.2 457.4 265.3 200.4 140.1 264.4 231.8 356.8 228.5 415.8 352.6 227.1 520.0 139.7 205.5 234.9 227.2 247.0 269.2 301.0 238.9 256.6 273.3 251.8 200.7 213.8 204.0 152.2 287.9 253.6 140.6 315.8 460.5 43.3 48.6 49.8 47.9 40.2 45.9 52.4 51.4 51.5 49.2 49.4 58.3 223.8 134.6 102.8 13.4 206.9 336.0 336.5 204.9 189.5 51.4 156.8 126.4 66.3 157.3 147.9 112.2 47.9 292.9 201.7 164.7 176.1 218.6 360.1 203.8 153.3 176.6 126.8 199.6 10.8 142.2 414.8 157.0 154.9 147.0 116.1 106.9 127.5 222.3 226.0 48.8 12.0 230.1 164.8 193.3 181.7 92.7 146.0 178.5 99.6 24.4 213.0 116.9 219.4 16.6 32.7 161.4 152.1 117.8 163.3 280.8 189.7 233.1 242.0 163.6 98.6 179.7 278.1 184.5 167.3 210.2 330.5 210.4 229.9 126.3 238.8 314.0 HSP90AB1 "HSPC2, HSPCB" ENSG00000096384 "Heat shock protein 90 alpha family class B member 1" P08238 6 44246166-44253888 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Stress response" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 4755.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005230, HPA055729, HPA072606, HPA074351" Enhanced Supported Cytosol "Intracellular and membrane" NA Yes 63000000 "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB005230: AB_2121392, HPA055729: AB_2682899, HPA072606: AB_2732203, HPA074351: AB_2732252" "unprognostic (6.12e-3)" "unprognostic (2.96e-3)" "unprognostic (4.72e-2)" "unprognostic (9.24e-2)" "unprognostic (4.20e-1)" "unprognostic (1.15e-3)" "unprognostic (1.76e-3)" "unprognostic (2.74e-1)" "unprognostic (7.97e-2)" "prognostic favorable (4.03e-4)" "unprognostic (1.31e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (9.94e-4)" "unprognostic (3.02e-1)" "unprognostic (9.53e-2)" "unprognostic (2.63e-1)" "unprognostic (1.06e-1)" 584.8 719.5 647.1 368.9 700.4 466.4 507.6 675.2 1529.5 581.3 651.0 425.3 215.8 594.2 540.1 463.8 708.5 332.5 783.8 699.9 811.5 494.6 396.5 526.9 427.7 707.0 738.2 1204.8 722.9 606.0 574.8 451.9 764.3 471.2 389.8 339.5 410.2 491.9 1379.0 483.7 332.6 526.8 655.1 346.0 538.8 251.6 745.8 362.1 456.8 998.8 571.4 525.0 509.4 818.8 2393.2 1495.7 1298.1 1606.0 871.2 904.4 1355.3 1049.1 1021.8 1898.3 1325.5 2254.5 708.0 3029.2 1106.3 1099.8 1928.1 1349.9 3197.5 1563.4 2326.7 1010.5 1292.5 2359.3 793.9 2978.8 628.9 2386.2 1563.2 842.6 1034.9 1495.5 1277.7 1658.4 1847.6 1533.9 3210.4 1095.1 1309.8 2404.3 2003.1 1432.6 1519.7 4378.9 1129.7 1900.7 1325.9 1658.7 1287.7 1422.1 1891.1 1154.8 816.3 1164.8 1526.2 1751.5 1518.6 1178.2 1169.0 1124.0 1875.7 931.1 2440.0 1255.6 2125.8 5370.7 1221.7 1720.8 1312.1 65.9 231.7 52.8 343.7 341.0 577.8 544.0 380.3 395.0 375.1 473.1 509.3 494.0 27.3 434.9 349.0 232.1 326.8 678.5 647.1 700.4 675.2 1529.5 699.9 811.5 707.0 738.2 764.3 655.1 745.8 818.8 1165.2 897.4 678.2 70.5 906.4 1059.3 4755.7 862.6 1331.1 329.3 938.9 1418.3 1407.0 519.0 942.6 366.0 227.2 1104.3 629.3 538.6 729.8 1011.1 185.5 1385.8 1359.6 1070.6 567.4 775.9 103.5 688.9 1107.1 1247.3 616.2 1444.8 1003.4 761.3 360.5 360.3 807.5 339.9 151.0 578.2 518.8 314.5 1262.5 198.4 686.0 896.7 736.4 76.8 573.3 326.1 200.8 69.9 127.4 811.7 504.8 611.2 725.0 1810.6 361.5 664.8 1219.1 262.1 348.4 1512.7 1437.2 266.1 694.1 1232.8 923.5 1123.3 1265.6 1350.0 739.6 2408.7 HSPA1B HSP70-2 ENSG00000204388 "Heat shock protein family A (Hsp70) member 1B" P0DMV9 6 31827738-31830254 "Predicted intracellular proteins" "Host-virus interaction, Stress response" "Chaperone, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 3007.4;Urothelial cells: 1619.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "Karpas-707: 204.3" "CAB008640, HPA052504" Approved Approved Nucleoplasm,Vesicles,Cytosol NA Yes "Cluster 18: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Cytosol" Nucleoplasm "CAB008640: AB_1617331, HPA052504: AB_2681854" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (4.23e-3)" "unprognostic (3.23e-2)" "unprognostic (3.54e-1)" "unprognostic (1.15e-1)" "unprognostic (2.76e-3)" "unprognostic (9.50e-2)" "unprognostic (3.45e-1)" "unprognostic (4.42e-2)" "unprognostic (6.92e-2)" "unprognostic (4.88e-2)" "unprognostic (5.74e-2)" "unprognostic (1.15e-1)" "unprognostic (9.17e-3)" "unprognostic (4.69e-2)" "unprognostic (5.99e-2)" 526.3 340.1 0.7 0.4 1.3 0.0 126.0 1.6 5.6 475.3 0.6 361.2 0.0 154.0 9.1 375.2 231.5 2.3 718.3 1.1 1.9 555.5 685.4 845.3 0.0 0.8 1.0 682.2 336.5 3.3 438.2 0.0 1.2 303.6 0.5 2.6 94.8 0.3 159.9 299.0 139.1 0.0 0.4 274.7 372.0 93.8 1.5 0.0 289.9 0.0 0.0 415.3 503.3 1.2 0.4 24.1 0.4 0.2 1.1 0.0 0.3 0.2 0.0 0.0 0.0 1.0 0.1 0.0 8.4 0.0 0.0 3.3 0.0 0.0 0.0 0.0 15.4 0.0 0.5 2.2 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 204.3 0.0 3.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.5 0.0 1.7 0.0 1.6 0.0 0.0 0.3 3.2 0.0 0.4 41.5 0.4 0.4 0.4 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 1.3 1.6 5.6 1.1 1.9 0.8 1.0 1.2 0.4 1.5 1.2 563.2 112.2 75.0 140.7 242.7 239.2 3007.4 63.2 630.0 44.6 509.4 403.9 512.3 40.0 73.7 69.9 131.3 82.7 82.8 542.8 19.6 45.5 1.9 434.9 380.2 446.2 318.6 57.9 2.7 15.6 140.8 585.8 595.8 710.4 346.8 14.1 25.7 17.7 142.0 47.1 2.8 426.3 61.1 84.4 1140.4 9.8 220.6 627.1 642.1 126.5 17.7 192.4 1.0 5.5 61.8 21.4 524.1 54.9 967.0 584.2 159.1 38.3 75.0 144.2 105.2 226.4 846.5 15.2 46.4 904.0 221.9 259.7 604.6 116.7 400.5 1619.4 HSPA8 "HSC70, HSC71, HSP73, HSPA10" ENSG00000109971 "Heat shock protein family A (Hsp70) member 8" P11142 11 123057489-123063230 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, Stress response, Transcription, Transcription regulation" "Chaperone, Hydrolase, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 2455.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002056, HPA052504" Uncertain Approved Nucleoplasm,Vesicles NA Yes 140000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm Vesicles "CAB002056: , HPA052504: AB_2681854" "unprognostic (2.28e-3)" "unprognostic (1.19e-3)" "prognostic favorable (6.14e-6)" "unprognostic (1.75e-1)" "unprognostic (1.84e-2)" "unprognostic (5.70e-2)" "prognostic unfavorable (1.93e-4)" "unprognostic (9.65e-3)" "unprognostic (3.82e-1)" "unprognostic (9.64e-2)" "unprognostic (2.93e-1)" "unprognostic (3.22e-1)" "prognostic favorable (3.81e-4)" "unprognostic (2.53e-1)" "unprognostic (1.83e-1)" "unprognostic (2.74e-1)" "unprognostic (7.16e-2)" 539.8 604.9 456.3 542.1 498.1 442.4 448.9 591.6 887.9 326.6 571.4 435.8 506.9 367.3 614.7 554.2 498.5 508.6 892.4 535.1 614.9 850.5 763.2 480.1 685.0 564.8 564.2 421.4 1238.1 593.8 501.9 487.1 620.0 411.2 525.8 531.5 404.1 439.8 1519.0 224.4 453.5 508.4 554.2 520.3 676.7 395.0 559.8 628.6 422.6 1508.5 879.6 866.0 302.4 656.8 1369.6 2077.3 1370.5 1176.5 1259.4 1337.4 1775.6 2730.9 1550.4 3373.2 2004.8 3151.7 1787.3 2318.5 1614.6 1591.9 2337.3 1835.9 4091.6 1027.2 3323.5 1955.4 605.9 2570.4 881.5 1532.0 347.5 2418.0 1757.1 721.8 1594.5 1045.0 320.7 1753.4 1845.6 321.7 2727.8 1147.0 2704.5 1235.5 2507.0 1761.3 2063.2 3463.3 1874.0 2214.4 962.2 1281.3 1665.1 1008.4 1371.8 1023.9 1980.4 2110.5 763.6 1491.1 1837.1 901.9 1767.0 1621.1 1246.1 1404.5 2402.7 740.6 1985.0 1890.9 1791.1 3316.9 1970.0 517.7 592.3 587.8 1245.4 1159.8 1499.6 1009.2 1441.8 1366.1 656.1 752.2 1367.5 1326.5 201.8 1110.7 1255.0 465.5 1761.7 3439.4 456.3 498.1 591.6 887.9 535.1 614.9 564.8 564.2 620.0 554.2 559.8 656.8 795.5 192.3 228.2 72.5 576.3 282.3 2455.6 315.3 507.6 206.7 454.5 380.1 396.3 278.8 352.8 130.6 127.2 926.1 740.3 513.1 528.3 589.0 49.8 404.1 380.1 512.8 519.8 551.7 33.4 628.8 1032.6 609.7 366.0 366.5 434.8 633.8 249.9 223.9 810.9 181.7 45.6 511.1 303.2 359.8 1060.8 58.2 222.4 590.6 528.3 35.6 530.9 307.4 639.5 28.1 50.3 513.8 552.1 270.0 573.6 779.5 823.0 1002.2 465.7 278.1 243.3 416.3 893.1 248.9 419.2 590.6 284.6 1512.1 1123.5 430.3 632.0 1171.5 HSPE1 "CPN10, EPF, GroES, HSP10" ENSG00000115541 "Heat shock protein family E (Hsp10) member 1" P61604 2 197500140-197503449 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Stress response" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1077.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 1907.6;Proximal tubular cells: 1978.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 4135.5" "Low region specificity" "Detected in all" "CAB017366, HPA038755, HPA048272" Supported NA Yes 2500000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 65: Brain - Ion transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "CAB017366: AB_10998950, HPA038755: AB_2676190, HPA048272: AB_2680336" "unprognostic (2.75e-2)" "unprognostic (6.89e-2)" "unprognostic (1.86e-1)" "unprognostic (1.43e-2)" "unprognostic (1.98e-1)" "unprognostic (1.85e-2)" "unprognostic (5.83e-3)" "unprognostic (4.14e-2)" "unprognostic (1.26e-2)" "unprognostic (2.94e-3)" "unprognostic (1.39e-2)" "unprognostic (6.21e-3)" "unprognostic (2.63e-1)" "unprognostic (4.51e-2)" "unprognostic (6.30e-2)" "unprognostic (1.94e-1)" "unprognostic (7.08e-3)" 152.1 709.5 383.2 143.9 387.5 116.8 212.7 410.3 1077.6 122.3 402.1 257.2 164.9 84.3 213.0 132.9 131.4 97.4 208.0 383.7 400.8 410.7 662.7 111.0 154.5 400.9 394.7 130.1 112.6 173.0 125.5 164.0 399.9 137.9 246.3 85.8 121.9 114.8 181.4 80.5 168.2 116.8 403.6 86.5 130.5 58.7 391.2 144.8 104.5 213.1 207.9 216.6 85.5 440.8 593.1 926.1 675.1 521.5 560.5 314.0 905.5 586.2 307.9 620.8 577.3 2796.6 504.6 1079.2 782.2 333.8 1542.1 510.4 1895.0 681.2 782.0 512.3 874.7 1099.8 1789.0 4135.5 239.0 1503.6 497.2 382.4 532.1 577.8 297.6 392.7 631.0 720.9 1588.2 338.0 481.1 1027.2 1107.2 1706.9 1077.5 985.2 1513.4 747.6 568.2 1388.5 967.4 1028.3 581.5 375.1 546.4 713.9 545.5 1588.2 287.1 881.7 355.7 466.1 643.3 501.0 1019.4 427.8 1016.0 1758.3 515.6 726.7 640.6 33.2 95.5 24.4 166.3 174.5 216.3 287.1 223.6 210.1 156.6 221.8 251.7 264.1 12.6 200.3 143.1 263.4 198.7 176.0 383.2 387.5 410.3 1077.6 383.7 400.8 400.9 394.7 399.9 403.6 391.2 440.8 341.6 195.5 160.2 0.0 380.6 435.1 1907.6 690.4 301.7 90.7 393.6 511.2 355.6 381.8 363.3 195.0 250.2 839.3 334.4 553.8 911.7 354.0 22.3 520.7 291.3 296.3 440.3 233.1 0.0 231.2 634.0 370.0 274.2 493.3 324.6 215.7 94.6 1092.0 517.2 63.9 0.0 605.0 427.2 150.6 616.4 36.1 216.6 534.4 409.1 0.0 214.2 204.2 133.9 0.0 0.0 285.3 466.2 141.8 323.4 830.7 562.1 1978.2 475.8 160.2 131.5 283.6 642.5 140.0 241.9 381.2 371.8 976.7 685.9 791.7 775.5 1111.7 HSPH1 "HSP105A, HSP105B, KIAA0201, NY-CO-25" ENSG00000120694 "Heat shock protein family H (Hsp110) member 1" Q92598 13 31134973-31162388 "Cancer-related genes, Predicted intracellular proteins" "Stress response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "brain: 1251.1" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 1316.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebral cortex: 1251.1" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002060, HPA028675, HPA031569" Uncertain Enhanced Nucleoplasm,Cytosol No Yes 1300000 "Cluster 27: Non-specific - Gene expression" "Cluster 10: Brain - Neuronal signaling" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" Cytosol Nucleoplasm "CAB002060: AB_563775, HPA028675: AB_10601581, HPA031569: AB_2673938" "unprognostic (1.10e-2)" "unprognostic (4.94e-2)" "unprognostic (5.44e-2)" "unprognostic (1.36e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.90e-4)" "prognostic unfavorable (1.41e-5)" "unprognostic (5.03e-2)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (1.53e-1)" "unprognostic (3.13e-1)" "unprognostic (7.45e-3)" "unprognostic (9.61e-2)" "unprognostic (2.58e-1)" "unprognostic (2.04e-1)" "unprognostic (7.89e-2)" 52.2 42.1 175.9 23.5 193.6 20.7 27.9 175.2 1251.1 25.0 182.5 29.3 11.3 25.9 37.6 35.8 54.8 32.3 57.3 184.9 189.3 73.5 47.6 66.6 34.9 172.7 180.7 56.3 28.6 30.3 63.8 37.8 180.9 28.4 25.3 26.7 20.1 29.3 36.6 21.7 20.4 28.0 177.2 32.3 53.1 67.8 190.2 37.4 32.2 32.6 45.1 58.8 35.4 227.4 69.9 130.7 105.1 10.2 99.1 56.0 70.0 117.8 104.6 179.0 82.8 154.9 105.4 179.6 71.9 82.4 253.7 131.2 411.7 104.8 229.2 141.6 51.7 155.7 69.3 137.2 32.3 109.1 118.8 35.5 236.5 119.6 68.3 93.0 105.4 62.0 132.7 27.8 127.4 94.7 158.1 124.2 150.3 338.6 96.6 122.5 85.8 58.9 135.0 83.5 108.5 90.1 107.4 104.0 56.6 160.6 35.0 104.7 64.4 61.3 77.4 89.2 132.4 21.8 76.0 150.6 51.0 129.8 104.7 1.4 5.0 2.7 7.6 12.2 9.4 11.1 9.7 11.8 8.4 10.6 14.7 13.8 0.5 16.7 19.6 6.6 7.0 7.7 175.9 193.6 175.2 1251.1 184.9 189.3 172.7 180.7 180.9 177.2 190.2 227.4 171.1 131.4 87.7 36.6 130.8 214.6 1316.2 44.7 175.2 38.7 152.2 143.3 163.6 40.0 123.3 46.0 417.0 23.2 78.9 153.2 29.4 49.8 100.0 346.1 140.1 132.3 227.7 58.9 121.0 35.9 64.2 249.6 94.3 250.6 248.6 61.7 26.4 25.7 90.6 30.3 77.7 159.0 65.1 38.6 452.1 36.5 33.8 281.3 163.7 55.3 42.6 28.2 26.8 30.7 53.2 45.5 154.0 39.1 142.0 426.3 18.2 31.6 290.5 79.0 39.5 98.1 153.1 161.3 164.6 151.1 143.3 42.5 363.8 58.5 166.1 511.8 INSR CD220 ENSG00000171105 "Insulin receptor" P06213 19 7112255-7294414 "CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Carbohydrate metabolism" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 9.8;granulocytes: 5.9;monocytes: 12.5" "Cell line enhanced" "Detected in many" "Karpas-707: 54.9;U-266/70: 40.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036302, HPA036303" Uncertain Approved "Vesicles,Plasma membrane" NA Yes 190000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 52: Non-specific - Transcription" Vesicles "Plasma membrane" "HPA036302: AB_2675048, HPA036303: " "unprognostic (4.64e-2)" "unprognostic (2.42e-1)" "unprognostic (9.65e-3)" "unprognostic (9.70e-2)" "unprognostic (1.44e-1)" "unprognostic (1.15e-2)" "unprognostic (2.58e-1)" "unprognostic (5.09e-2)" "unprognostic (1.97e-1)" "unprognostic (3.05e-1)" "unprognostic (9.29e-2)" "unprognostic (1.86e-1)" "unprognostic (6.33e-2)" "unprognostic (3.45e-3)" "unprognostic (2.43e-1)" "unprognostic (2.75e-1)" "unprognostic (8.82e-2)" 13.0 22.6 12.5 2.8 16.8 5.6 13.0 17.3 12.8 14.6 18.8 15.0 10.0 18.4 6.3 4.1 16.9 8.2 26.3 10.0 12.2 21.8 33.0 7.2 2.3 18.3 16.3 39.9 64.2 13.0 16.3 7.4 18.7 15.2 10.4 6.5 16.9 9.9 23.5 11.5 12.2 11.5 14.1 48.2 12.5 5.4 16.6 2.7 14.5 13.3 3.5 12.3 9.2 22.5 6.2 3.2 3.6 5.7 18.8 6.1 11.1 3.5 2.9 1.6 1.6 8.4 7.0 9.0 8.2 6.8 4.0 1.6 8.9 1.4 1.2 0.0 6.4 0.0 2.3 22.6 8.2 4.3 6.7 10.0 4.5 0.2 4.9 4.2 3.8 4.8 9.5 54.9 1.8 3.2 3.1 7.8 3.3 3.8 5.2 29.0 2.1 7.6 0.1 27.8 6.6 5.2 6.5 3.8 3.3 6.4 1.4 21.6 3.6 3.4 2.1 8.2 5.1 40.4 23.9 20.2 4.3 7.3 0.0 2.7 8.6 5.9 0.2 8.8 0.3 0.8 0.3 0.1 9.8 1.1 0.7 0.1 1.9 1.0 12.5 8.2 0.0 1.6 12.5 16.8 17.3 12.8 10.0 12.2 18.3 16.3 18.7 14.1 16.6 22.5 75.6 48.1 34.7 64.9 10.6 64.9 63.6 34.7 8.0 40.4 134.0 76.2 92.1 137.2 83.3 62.5 79.2 17.8 6.7 124.1 15.6 55.1 4.7 26.8 106.8 123.9 163.6 25.0 68.3 78.7 53.7 43.7 20.4 42.1 3.8 168.4 255.2 246.0 9.2 38.7 100.8 97.3 32.6 49.0 31.1 9.0 96.3 35.0 51.6 62.8 24.2 31.6 0.0 62.8 183.5 50.7 68.8 245.3 21.8 107.9 122.9 114.1 65.3 23.6 59.2 37.6 44.2 5.2 3.6 3.2 68.8 38.3 4.7 81.4 65.2 130.0 IRF2BPL "C14orf4, EAP1, KIAA1865" ENSG00000119669 "Interferon regulatory factor 2 binding protein like" Q9H1B7 14 77024543-77028708 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050862, HPA061333" Approved Enhanced Nucleoplasm NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA050862: AB_2681258, HPA061333: AB_2684481" "unprognostic (5.58e-2)" "unprognostic (6.48e-2)" "unprognostic (1.99e-3)" "prognostic unfavorable (5.52e-4)" "unprognostic (8.78e-3)" "unprognostic (1.57e-2)" "unprognostic (2.70e-1)" "unprognostic (1.81e-1)" "unprognostic (5.74e-2)" "unprognostic (2.53e-2)" "unprognostic (2.51e-3)" "unprognostic (5.39e-2)" "unprognostic (1.03e-3)" "unprognostic (2.55e-1)" "unprognostic (9.33e-2)" "unprognostic (1.14e-1)" "unprognostic (1.58e-2)" 26.1 25.3 12.2 9.2 13.9 5.6 28.5 13.4 12.0 20.1 12.8 32.4 6.9 25.8 5.1 13.3 33.7 6.5 22.6 14.1 21.1 28.7 19.1 20.9 6.2 15.2 14.8 32.4 17.5 19.8 22.6 7.9 10.9 18.4 3.3 7.3 19.2 10.1 16.8 25.2 15.1 8.0 12.6 19.0 18.8 13.5 19.0 9.7 18.7 4.2 3.3 26.4 18.2 9.4 15.4 13.2 32.2 36.3 9.6 8.8 45.8 15.9 13.0 4.4 5.9 6.2 24.8 5.4 11.3 13.6 12.4 23.6 5.6 11.8 3.7 25.8 19.1 6.9 13.0 8.5 12.5 1.9 29.7 11.8 9.1 7.8 6.8 34.8 6.0 10.9 10.4 59.4 5.7 42.2 21.0 14.5 14.5 6.6 68.2 4.4 9.1 13.0 15.6 22.4 24.9 36.0 22.5 23.2 42.5 8.6 16.1 3.4 10.4 20.2 19.5 6.8 10.3 22.9 26.3 9.0 31.3 4.7 25.8 1.7 1.4 1.3 2.8 1.9 2.7 1.4 2.5 2.6 1.3 1.6 2.0 2.3 9.0 5.9 2.3 10.7 2.6 0.8 12.2 13.9 13.4 12.0 14.1 21.1 15.2 14.8 10.9 12.6 19.0 9.4 71.4 22.4 14.3 5.9 40.2 73.7 32.5 22.5 115.5 57.1 54.6 41.5 19.5 32.9 11.6 64.4 29.2 22.8 58.9 10.8 37.2 19.6 1.3 25.3 26.0 44.0 47.6 10.8 8.2 19.0 49.7 47.8 12.2 25.6 26.6 15.2 55.6 60.5 33.3 10.1 8.6 14.7 16.2 54.7 78.9 4.0 30.1 26.6 35.6 9.4 10.0 57.8 38.1 8.5 4.8 17.8 7.0 34.3 21.1 30.0 6.7 23.1 13.8 10.4 39.5 56.4 83.2 1.6 50.5 54.2 50.6 46.0 39.0 27.5 12.8 20.6 ITPR3 IP3R3 ENSG00000096433 "Inositol 1,4,5-trisphosphate receptor type 3" Q14573 6 33620365-33696574 "Human disease related genes, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 123.0;Gastric mucus-secreting cells: 127.4;Late spermatids: 220.4;Pancreatic endocrine cells: 89.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 164.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA003915, HPA064704" Approved Uncertain Vesicles No Yes "Cluster 44: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA003915: AB_1851845, HPA064704: " "unprognostic (2.57e-1)" "unprognostic (2.81e-2)" "unprognostic (1.52e-2)" "unprognostic (2.30e-1)" "unprognostic (5.40e-2)" "unprognostic (1.24e-1)" "unprognostic (2.08e-2)" "unprognostic (6.14e-2)" "unprognostic (3.35e-1)" "unprognostic (3.08e-2)" "unprognostic (4.14e-3)" "unprognostic (1.88e-1)" "unprognostic (6.44e-3)" "unprognostic (5.01e-2)" "unprognostic (1.74e-1)" "unprognostic (8.89e-2)" "unprognostic (2.43e-2)" 16.3 11.4 5.5 17.0 5.0 6.1 14.6 3.8 5.3 18.0 3.7 26.2 29.1 8.5 13.1 18.1 14.0 15.3 15.0 3.8 3.9 16.4 2.2 30.6 20.4 5.6 5.0 13.5 11.3 2.8 7.4 4.3 5.2 13.9 18.4 0.8 18.5 11.2 4.5 58.9 35.1 4.7 4.7 39.8 41.5 15.4 7.0 14.3 54.0 5.1 21.0 12.1 24.0 3.9 73.7 34.0 6.3 0.3 6.2 19.3 40.9 24.8 62.8 30.5 27.4 46.7 55.9 62.6 26.1 17.9 76.1 70.9 28.6 66.7 15.7 36.8 24.0 0.1 102.6 52.0 14.1 11.3 7.9 14.0 59.2 76.7 164.7 66.5 52.1 24.5 25.0 19.7 33.3 35.0 19.0 6.4 6.2 55.8 49.4 29.0 0.1 37.1 107.6 50.9 57.3 2.1 42.8 61.6 60.2 6.9 21.2 5.9 71.8 41.1 20.1 53.1 55.2 13.5 14.3 29.4 32.8 16.6 24.1 0.8 0.0 0.0 0.8 0.0 0.6 0.4 0.4 0.5 0.0 0.6 0.4 0.5 0.0 0.0 0.0 0.0 0.7 0.2 5.5 5.0 3.8 5.3 3.8 3.9 5.6 5.0 5.2 4.7 7.0 3.9 12.4 48.1 58.9 0.3 13.5 26.5 10.9 27.9 18.2 1.5 9.3 9.9 2.7 12.8 20.2 31.3 0.0 0.3 10.9 52.9 0.0 28.4 123.0 19.1 9.1 18.2 23.9 6.6 1.1 30.2 6.3 9.2 127.4 43.1 0.0 0.2 12.5 0.4 0.5 0.0 1.6 41.6 10.2 0.6 6.9 220.4 23.3 2.6 12.4 23.4 3.2 0.4 4.1 0.5 0.4 89.7 41.6 13.9 18.7 20.5 45.9 0.2 12.1 1.2 6.6 3.9 3.3 1.6 3.2 14.5 25.4 0.5 13.1 5.8 35.6 20.7 KANK2 "ANKRD25, KIAA1518, MXRA3" ENSG00000197256 "KN motif and ankyrin repeat domains 2" Q63ZY3 19 11164270-11197791 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 402.5;Endometrial stromal cells: 149.6;Leydig cells: 126.2;Peritubular cells: 225.7;Smooth muscle cells: 131.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "ASC diff: 327.8;ASC TERT1: 365.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015643 Approved Approved Nucleoplasm,Cytosol NA Yes "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm Cytosol "HPA015643: AB_1844839" "unprognostic (2.37e-1)" "unprognostic (8.03e-2)" "unprognostic (1.15e-2)" "unprognostic (1.30e-1)" "unprognostic (1.00e-1)" "unprognostic (3.23e-3)" "unprognostic (1.54e-1)" "unprognostic (8.63e-2)" "unprognostic (8.98e-2)" "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (8.73e-5)" "unprognostic (4.01e-2)" "unprognostic (1.37e-1)" "unprognostic (1.13e-1)" "unprognostic (1.48e-2)" 150.2 55.5 25.7 50.5 27.2 17.9 97.7 22.8 25.6 275.3 24.5 413.2 36.8 376.9 64.6 139.1 222.1 125.0 200.5 20.0 27.9 54.1 51.3 134.5 20.7 29.5 26.5 213.9 35.4 14.3 29.8 62.3 29.0 140.5 58.7 19.0 39.3 173.6 56.9 49.7 108.0 277.7 23.8 57.8 123.7 25.0 29.5 15.7 71.7 51.1 12.4 255.2 148.5 22.6 42.4 91.1 28.3 30.3 327.8 365.1 20.2 188.9 161.0 92.1 76.2 36.3 27.0 177.2 88.1 234.3 59.6 40.0 25.6 13.7 61.3 9.3 18.4 77.2 105.6 37.5 123.9 11.8 21.4 158.7 20.1 67.3 9.0 237.2 37.8 5.5 51.5 14.3 143.6 75.7 2.3 9.9 31.4 27.5 95.1 59.7 234.8 42.2 65.4 22.7 16.6 51.7 188.2 16.4 22.4 32.7 25.1 41.2 139.1 131.5 52.6 170.1 75.2 13.7 32.9 61.3 111.0 66.3 136.4 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 25.7 27.2 22.8 25.6 20.0 27.9 29.5 26.5 29.0 23.8 29.5 22.6 34.1 57.7 28.3 7.8 1.3 6.2 5.5 5.2 2.2 2.0 5.2 7.1 402.5 27.1 12.0 20.2 20.9 6.9 0.6 2.5 3.9 8.1 2.4 12.7 149.6 41.2 0.0 76.2 0.9 4.4 4.9 69.2 13.3 11.9 7.6 7.7 32.5 28.2 22.5 0.0 4.1 2.6 4.1 10.6 15.1 3.8 126.2 6.3 8.8 42.2 0.5 34.9 4.1 1.0 1.4 11.9 1.2 225.7 0.8 6.7 1.6 3.7 8.0 23.4 92.1 79.2 131.0 1.8 7.2 2.8 7.7 2.3 2.3 7.7 5.2 8.4 KDM5B "CT31, JARID1B, PLU-1, PPP1R98, RBBP2H1A" ENSG00000117139 "Lysine demethylase 5B" Q9UGL1 1 202724495-202808487 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase, Repressor" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 62.3" "Cell type enhanced" "Detected in all" "Late spermatids: 243.6;Spermatocytes: 390.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027179, HPA053723, CAB068193" Enhanced Supported Nucleoplasm,Cytosol NA Yes "Cluster 10: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "CAB068193: AB_2665696, HPA027179: AB_1851987, HPA053723: AB_2682241" "unprognostic (1.19e-1)" "unprognostic (1.74e-2)" "unprognostic (1.03e-1)" "unprognostic (4.67e-2)" "unprognostic (1.92e-2)" "unprognostic (2.31e-1)" "unprognostic (3.49e-3)" "unprognostic (3.02e-2)" "unprognostic (3.23e-2)" "unprognostic (6.12e-2)" "unprognostic (1.61e-2)" "unprognostic (4.79e-2)" "unprognostic (8.25e-3)" "unprognostic (2.56e-2)" "unprognostic (1.61e-1)" "unprognostic (5.56e-2)" "unprognostic (4.13e-1)" 9.1 7.7 1.5 2.6 2.2 14.1 9.9 5.8 4.8 14.7 7.9 10.6 2.1 12.6 3.3 21.0 9.9 2.9 6.0 4.6 1.5 6.2 4.6 10.8 2.2 0.8 0.4 12.8 8.3 2.6 6.9 4.7 0.2 10.6 2.2 17.8 12.5 2.4 4.7 24.3 8.6 3.1 1.0 7.4 8.7 62.3 1.2 4.1 8.4 0.8 2.1 10.9 15.7 2.3 9.9 2.4 14.0 9.8 7.2 6.6 23.7 6.2 9.4 6.2 6.4 2.2 8.8 0.1 5.7 7.9 2.3 11.8 9.0 8.3 5.4 0.5 12.8 7.7 2.4 1.9 5.5 17.7 8.9 9.4 12.1 7.0 7.2 10.1 11.7 7.3 20.9 0.3 4.9 6.3 5.8 16.4 21.9 4.3 28.0 18.7 0.1 0.4 6.5 10.7 10.7 23.4 14.7 7.9 8.7 15.7 16.6 10.5 12.8 8.2 5.8 1.4 5.2 2.3 1.1 8.2 6.0 5.5 4.1 44.6 6.4 19.6 7.7 4.8 4.6 10.9 8.9 4.3 4.2 17.4 9.6 6.0 34.4 12.9 10.4 6.6 7.2 3.9 1.5 2.2 5.8 4.8 4.6 1.5 0.8 0.4 0.2 1.0 1.2 2.3 24.5 89.8 38.5 46.7 22.2 64.4 34.8 53.0 84.2 35.5 57.1 50.0 9.5 11.5 53.6 16.5 62.6 41.8 12.4 23.7 5.9 47.6 191.6 65.2 71.8 31.9 43.6 50.2 75.8 22.3 34.3 42.7 47.9 69.5 27.1 28.6 17.2 10.9 7.7 15.2 53.5 38.1 44.7 15.1 21.9 243.6 36.4 15.5 26.6 40.3 11.3 69.8 10.3 39.7 42.5 45.4 21.8 32.7 25.8 43.1 15.2 8.2 61.9 138.6 32.9 22.8 40.2 390.9 71.0 95.9 116.2 82.4 21.2 61.5 30.2 55.6 KIF20A RAB6KIFL ENSG00000112984 "Kinesin family member 20A" O95235 5 138178719-138187723 "Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.1;lymphoid tissue: 24.6;testis: 11.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 11.0;Erythroid cells: 24.6;Extravillous trophoblasts: 13.1;Granulosa cells: 11.1;Spermatocytes: 21.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "NK-cell: 6.6;T-reg: 2.5" "Group enriched" "Detected in many" 46 "NK-cells: 6.6;T-cells: 2.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA036909, HPA036910" Approved Uncertain "Nucleoplasm,Cytokinetic bridge" Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytokinetic bridge" "HPA036909: AB_10670245, HPA036910: AB_10671716" "unprognostic (7.50e-2)" "unprognostic (2.43e-1)" "unprognostic (1.39e-3)" "unprognostic (1.21e-2)" "unprognostic (3.47e-2)" "unprognostic (2.60e-2)" "prognostic unfavorable (2.14e-12)" "prognostic unfavorable (6.79e-4)" "unprognostic (2.86e-2)" "unprognostic (3.16e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (9.73e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (9.05e-2)" "unprognostic (2.61e-1)" "unprognostic (1.09e-1)" "unprognostic (3.16e-1)" 0.7 0.8 0.0 4.5 0.1 14.1 1.3 0.1 0.1 1.0 0.1 3.3 3.5 1.4 0.0 6.6 0.4 0.8 0.5 0.0 0.1 0.4 0.9 0.9 8.6 0.1 0.2 0.2 0.2 0.1 0.0 5.4 0.1 0.2 5.1 0.0 1.0 0.1 0.1 4.4 2.8 5.8 0.0 1.9 2.1 11.7 0.5 24.6 0.5 0.1 13.1 1.6 2.0 0.1 87.8 59.5 127.8 84.4 6.7 12.3 53.9 75.0 68.9 162.3 121.4 111.9 80.5 38.8 39.2 96.5 60.6 85.9 121.7 142.5 160.9 56.4 57.4 57.2 101.1 70.7 0.3 28.2 25.1 4.8 2.3 86.2 49.5 27.1 106.7 53.9 24.4 70.4 113.9 81.5 47.6 26.7 80.6 51.8 63.7 51.2 128.5 39.5 43.9 42.3 37.8 37.5 144.1 47.9 30.9 161.6 60.8 28.5 51.1 41.6 60.5 38.0 126.4 36.0 37.5 42.0 26.7 81.1 82.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 2.5 0.3 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.5 0.1 0.3 0.0 1.7 0.0 0.8 0.4 0.4 2.9 0.0 0.0 1.1 1.3 0.3 0.0 0.7 0.0 0.0 11.0 0.1 2.8 0.0 0.1 1.0 1.0 1.9 1.7 0.0 24.6 0.0 0.0 13.1 3.1 2.6 1.3 4.5 11.1 3.3 0.4 6.1 0.0 0.0 1.6 6.1 2.2 0.4 2.0 0.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.4 3.0 0.3 1.2 0.0 0.9 0.0 0.0 0.5 4.4 21.7 7.5 5.3 0.4 1.0 0.7 0.8 3.4 0.6 KIF5B "KNS, KNS1" ENSG00000170759 "Kinesin family member 5B" P33176 10 32009015-32056425 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Motor protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009846, HPA037589, HPA037590" Approved Enhanced "Centriolar satellite,Cytosol" NA Yes 97000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 10: Non-specific - Unknown function" "Centriolar satellite, Cytosol" "CAB009846: AB_2280915, HPA037589: AB_2675563, HPA037590: AB_2675564" "unprognostic (4.94e-3)" "unprognostic (1.70e-1)" "unprognostic (1.06e-1)" "unprognostic (1.84e-1)" "unprognostic (4.00e-2)" "unprognostic (6.21e-2)" "unprognostic (1.06e-2)" "unprognostic (1.84e-1)" "unprognostic (2.70e-1)" "unprognostic (6.37e-3)" "unprognostic (2.03e-1)" "unprognostic (2.60e-1)" "unprognostic (1.81e-1)" "unprognostic (2.43e-2)" "unprognostic (2.39e-1)" "unprognostic (8.06e-2)" "unprognostic (1.76e-1)" 59.7 41.8 110.0 46.7 128.2 84.9 45.3 107.7 149.7 47.3 75.6 66.4 52.0 54.1 30.3 52.7 39.2 59.8 87.4 85.8 100.2 44.7 31.9 52.5 39.9 121.9 123.8 27.6 41.8 91.6 22.9 54.4 120.6 65.9 63.6 45.1 39.1 52.0 65.0 38.9 54.7 81.3 128.1 48.1 51.4 64.4 116.8 44.0 50.5 67.3 36.6 60.8 29.8 143.4 115.8 96.4 127.3 89.9 89.2 97.7 54.4 155.6 73.3 117.6 99.6 106.6 124.0 78.7 65.8 185.8 66.9 93.3 117.6 99.4 156.4 68.4 64.1 100.2 87.9 104.5 102.5 70.5 105.6 79.9 138.0 135.8 94.0 93.4 152.8 68.2 122.9 80.5 164.7 69.7 74.0 39.7 20.7 110.1 43.4 95.7 237.2 32.6 90.6 79.5 123.3 89.9 120.4 47.5 117.3 88.0 57.5 99.4 128.4 118.7 111.0 139.3 117.2 24.2 29.8 90.9 113.2 142.2 114.1 41.8 25.9 44.0 19.1 33.0 18.7 23.7 24.0 20.6 24.7 24.3 21.1 20.8 51.1 24.3 35.7 47.9 29.4 18.4 110.0 128.2 107.7 149.7 85.8 100.2 121.9 123.8 120.6 128.1 116.8 143.4 160.3 182.7 206.8 49.3 86.3 213.1 177.7 200.6 66.0 181.9 119.0 103.8 396.0 115.8 198.4 104.8 100.1 121.0 125.5 145.0 45.0 209.4 185.5 167.8 171.4 181.0 132.3 69.2 44.6 176.0 134.9 141.2 85.6 158.9 91.2 159.7 88.5 46.2 132.7 151.4 56.0 227.3 213.6 111.8 129.1 51.8 59.0 137.2 101.4 84.3 169.3 160.5 82.4 61.9 83.3 202.2 164.9 130.9 84.2 254.1 120.2 59.5 206.1 123.8 85.5 176.0 244.8 566.0 195.6 87.6 236.7 331.9 116.0 137.4 208.1 246.8 KNTC1 "KIAA0166, ROD" ENSG00000184445 "Kinetochore associated 1" P50748 12 122527246-122626396 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 42.3" "Cell type enhanced" "Detected in many" "Early spermatids: 30.4;Erythroid cells: 29.5;Plasma cells: 28.7;Spermatocytes: 40.7;Spermatogonia: 39.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA025241 Approved Supported "Plasma membrane,Cytosol" NA Yes "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Plasma membrane" "HPA025241: AB_1852629" "unprognostic (1.17e-1)" "unprognostic (2.12e-3)" "unprognostic (2.51e-1)" "unprognostic (1.53e-2)" "unprognostic (9.34e-2)" "prognostic favorable (8.69e-4)" "prognostic unfavorable (4.79e-6)" "unprognostic (4.04e-2)" "unprognostic (7.20e-3)" "unprognostic (1.59e-2)" "unprognostic (4.78e-2)" "unprognostic (1.92e-2)" "prognostic unfavorable (7.89e-8)" "unprognostic (2.17e-2)" "unprognostic (3.08e-1)" "unprognostic (8.04e-2)" "unprognostic (1.74e-1)" 7.1 7.6 3.7 11.7 3.6 42.3 7.6 4.9 5.3 9.1 3.5 9.8 9.0 5.3 5.2 12.2 6.8 3.4 4.1 3.6 3.4 6.7 6.4 8.0 16.4 3.8 3.4 8.2 6.6 2.9 5.7 5.8 3.9 7.3 11.9 5.5 7.7 2.9 2.5 15.1 14.5 4.6 3.1 18.2 7.2 28.2 4.0 17.8 5.4 1.4 17.4 6.2 8.9 5.0 33.8 27.6 77.8 17.9 5.9 10.8 35.0 30.6 19.8 29.7 27.9 26.2 27.6 40.2 15.6 14.9 19.5 45.4 34.1 19.1 39.1 28.8 23.7 49.7 57.1 27.1 2.0 49.3 32.8 5.8 4.3 30.7 20.2 15.5 20.5 50.5 50.4 29.4 22.6 25.0 40.9 113.0 39.4 16.3 34.5 55.4 37.8 44.8 17.8 35.6 24.1 31.0 55.7 11.7 16.7 46.2 44.4 28.1 15.1 33.7 32.3 33.3 36.3 39.3 42.3 61.0 20.1 31.3 39.6 2.5 0.5 1.8 0.7 0.7 0.6 1.6 1.1 1.3 0.5 0.9 0.8 1.0 1.6 0.9 1.0 0.8 0.5 0.3 3.7 3.6 4.9 5.3 3.6 3.4 3.8 3.4 3.9 3.1 4.0 5.0 4.3 0.0 2.6 3.3 8.1 4.2 1.9 1.9 2.2 2.2 3.1 3.4 1.8 0.0 1.9 5.5 4.2 7.0 3.8 3.0 0.0 1.5 30.4 3.3 3.9 2.9 0.0 29.5 6.2 0.4 5.9 2.9 10.2 5.2 1.3 14.7 2.2 1.3 4.8 0.0 4.5 2.3 0.0 2.2 4.7 17.7 4.7 4.0 1.8 4.7 1.6 1.1 2.1 2.5 4.4 0.8 1.0 3.0 28.7 1.0 1.5 0.5 5.0 5.0 6.6 3.1 2.9 40.7 39.9 4.9 2.3 2.9 5.3 2.1 5.8 1.6 LGALS1 GBP ENSG00000100097 "Galectin 1" P09382 22 37675636-37679802 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3949.7;Langerhans cells: 4906.5;monocytes: 7118.4;Smooth muscle cells: 4703.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 1649.6" "HPA000646, HPA000687, HPA001130, CAB002157" Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" No Yes 10000000 20000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" Cytosol Nucleoplasm "CAB002157: AB_563734, HPA000646: AB_1078935, HPA000687: AB_2756309, HPA001130: AB_2756311" "unprognostic (1.65e-1)" "unprognostic (8.13e-2)" "unprognostic (5.13e-2)" "prognostic favorable (2.36e-5)" "unprognostic (6.38e-2)" "unprognostic (2.67e-3)" "prognostic unfavorable (3.06e-4)" "unprognostic (3.22e-3)" "unprognostic (4.91e-3)" "unprognostic (2.51e-1)" "unprognostic (6.16e-3)" "unprognostic (8.06e-2)" "prognostic unfavorable (1.18e-10)" "unprognostic (2.24e-2)" "unprognostic (8.13e-2)" "unprognostic (9.47e-2)" "prognostic unfavorable (5.10e-4)" 1921.2 778.5 482.4 523.8 520.7 324.7 1490.9 613.5 695.3 1805.7 465.2 1634.7 197.7 2270.1 196.8 387.4 1147.0 556.0 1397.4 457.7 549.0 362.4 277.4 920.2 176.7 694.5 576.1 1440.2 155.5 188.1 254.8 426.1 661.5 903.0 207.2 39.5 397.5 756.3 1172.9 472.8 475.3 1353.4 593.8 460.7 582.7 244.9 624.9 153.9 290.9 691.9 116.9 1059.7 1156.4 782.4 2850.9 1664.3 36.5 1440.9 3314.6 6505.1 32.7 6450.7 7619.4 4761.9 4716.9 189.6 368.3 3.3 649.1 6661.4 1609.2 296.3 58.8 4309.2 1663.3 2917.2 30.9 251.3 1606.3 791.1 2155.3 145.1 3167.7 4031.7 294.2 3785.7 1609.9 4271.1 5325.7 1.7 186.6 1163.4 3771.1 1287.6 5.2 2038.4 14.3 629.6 3914.9 5.4 2388.6 799.7 2000.0 6.4 5.5 843.4 1287.4 224.3 1644.5 66.7 1187.2 1689.0 7122.0 6224.0 3070.2 2788.9 3349.3 701.8 530.6 13.6 7291.9 762.0 2535.9 1086.5 3047.4 110.2 766.5 2320.4 113.6 567.7 694.9 754.2 3653.1 287.5 114.3 478.1 122.2 415.4 2556.7 899.2 1514.7 4667.0 482.4 520.7 613.5 695.3 457.7 549.0 694.5 576.1 661.5 593.8 624.9 782.4 1505.8 166.7 90.4 12.7 294.3 730.3 144.0 2796.6 49.5 10.0 144.2 477.9 986.3 74.4 213.4 163.7 6.2 88.0 466.5 49.9 17.6 690.2 30.9 183.0 3011.6 1063.6 3.0 74.9 7.5 90.4 1573.3 2540.4 28.1 230.3 540.0 172.2 653.2 614.1 3949.7 8.4 5.4 8.4 339.7 2159.0 4906.5 106.4 975.5 1700.0 2856.6 15.9 7118.4 278.0 588.1 4.0 17.1 233.5 6.1 1300.7 590.9 118.8 0.5 28.7 109.8 45.4 1650.1 1873.6 4703.8 33.8 13.1 18.2 588.0 151.5 767.5 197.2 11.6 57.0 LTBR "D12S370, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFRSF3" ENSG00000111321 "Lymphotoxin beta receptor" P36941 12 6375045-6391571 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Host-virus interaction" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 71.3;intermediate monocyte: 66.3;myeloid DC: 49.8;neutrophil: 45.0;non-classical monocyte: 50.1" "Group enriched" "Detected in many" 36 "dendritic cells: 49.8;granulocytes: 45.0;monocytes: 71.3" "Cell line enhanced" "Detected in many" "HHSteC: 393.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026202, HPA061617" Uncertain Supported "Golgi apparatus" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Golgi apparatus" "CAB026202: , HPA061617: AB_2732666" "unprognostic (2.60e-2)" "unprognostic (1.24e-2)" "unprognostic (7.75e-3)" "unprognostic (2.23e-2)" "unprognostic (3.01e-2)" "unprognostic (3.24e-3)" "prognostic unfavorable (5.13e-4)" "unprognostic (2.08e-2)" "unprognostic (2.24e-2)" "unprognostic (1.43e-1)" "unprognostic (2.45e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (5.92e-4)" "unprognostic (3.66e-2)" "unprognostic (9.84e-3)" "unprognostic (6.91e-2)" "unprognostic (2.86e-1)" 67.6 64.4 13.9 36.4 14.6 11.7 60.3 14.7 15.9 65.8 18.0 72.7 48.6 68.1 20.7 81.3 49.6 48.3 37.2 13.3 15.8 55.1 135.8 66.0 14.6 19.6 17.3 46.3 78.7 54.9 26.3 48.6 18.8 61.9 34.3 1.9 61.5 44.0 26.3 75.1 51.1 62.6 17.4 44.8 67.7 13.3 18.1 11.7 57.2 23.5 18.0 65.8 65.1 17.0 98.2 130.3 0.0 41.1 245.9 183.7 89.9 67.9 153.1 98.8 101.1 62.0 148.7 0.1 39.5 145.7 0.5 112.2 0.5 140.5 38.9 0.0 0.2 58.1 53.2 36.6 393.1 4.1 94.6 270.8 255.2 70.7 197.1 102.6 91.2 0.0 55.5 0.5 115.0 93.5 0.4 29.3 1.2 155.7 74.4 0.0 6.6 0.2 149.2 112.2 0.7 0.5 63.6 122.9 143.6 5.0 20.5 105.3 58.0 34.6 39.6 129.0 72.1 0.0 0.4 0.1 14.6 35.9 129.5 5.4 71.3 0.5 0.2 66.3 0.0 0.1 0.1 0.1 49.8 0.1 0.3 0.2 45.0 1.5 50.1 11.8 0.1 27.2 13.9 14.6 14.7 15.9 13.3 15.8 19.6 17.3 18.8 17.4 18.1 17.0 47.0 60.9 68.9 2.9 3.6 39.0 87.2 46.4 72.3 4.1 33.9 35.9 15.5 45.8 60.7 31.3 0.0 31.3 12.4 78.3 9.8 52.2 0.7 23.8 48.6 49.3 52.0 15.8 0.5 99.8 43.6 50.5 89.7 45.2 29.7 30.1 50.7 66.5 48.7 0.0 0.5 57.1 34.6 77.3 34.6 5.1 52.8 50.8 23.2 14.0 43.1 9.6 11.3 5.5 1.1 69.5 82.3 39.9 3.3 110.7 136.9 30.1 42.8 1.6 26.3 33.1 42.0 1.6 0.9 78.9 61.7 37.5 4.9 28.0 63.4 97.6 LZTS2 "KIAA1813, LAPSER1" ENSG00000107816 "Leucine zipper tumor suppressor 2" Q9BRK4 10 100996618-101007836 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 70.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044956 Approved Approved "Plasma membrane,Cytosol" No Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "HPA044956: AB_10795989" "unprognostic (1.42e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (8.23e-4)" "unprognostic (8.18e-2)" "unprognostic (4.64e-2)" "unprognostic (1.56e-1)" "unprognostic (5.49e-3)" "unprognostic (3.56e-1)" "unprognostic (7.57e-2)" "unprognostic (4.58e-2)" "unprognostic (2.72e-1)" "unprognostic (1.38e-1)" "prognostic unfavorable (3.39e-4)" "unprognostic (7.63e-2)" "unprognostic (1.86e-1)" "unprognostic (5.46e-3)" "unprognostic (1.76e-3)" 69.9 66.0 46.8 14.9 65.5 14.4 63.3 58.0 54.1 74.3 25.8 96.3 17.5 90.3 17.7 41.0 69.2 19.8 58.9 41.2 45.8 51.8 18.0 57.1 12.1 63.7 64.3 78.6 29.5 29.1 43.6 28.5 58.5 69.5 8.9 5.9 44.3 40.6 37.8 48.9 43.0 26.6 49.0 44.4 54.9 36.2 64.1 10.8 57.6 18.0 8.1 84.1 54.4 78.9 32.9 43.1 34.6 59.7 45.0 36.3 70.8 38.7 72.8 31.9 36.0 50.5 26.6 13.1 35.1 52.5 23.0 54.6 21.5 28.2 7.8 12.8 31.9 12.1 46.4 66.3 63.6 6.4 15.2 66.1 20.2 25.1 30.1 67.3 32.8 15.6 38.7 7.3 28.7 31.6 5.8 15.8 38.8 12.6 35.2 74.7 101.3 13.5 24.4 39.3 8.4 62.8 26.3 11.9 99.9 18.6 61.0 51.6 42.1 37.9 42.6 40.5 20.7 14.0 10.2 3.3 64.0 17.7 19.4 0.0 0.7 0.4 2.7 0.4 3.7 2.3 3.4 3.0 1.1 2.9 3.5 3.0 0.3 2.9 0.1 1.8 3.0 1.5 46.8 65.5 58.0 54.1 41.2 45.8 63.7 64.3 58.5 49.0 64.1 78.9 34.7 16.0 10.5 20.2 5.3 13.4 9.0 12.4 19.4 14.4 21.7 20.3 5.2 11.5 9.4 5.5 6.2 18.6 1.9 8.0 7.9 19.1 6.8 7.9 20.5 22.9 16.7 5.0 6.8 12.6 13.2 21.8 14.8 13.0 1.3 38.9 18.5 2.6 22.2 18.5 7.7 17.8 16.2 7.2 9.2 4.1 25.7 8.4 16.0 13.1 4.8 18.9 4.1 9.0 70.3 13.3 7.9 29.3 5.4 18.1 6.5 8.3 6.1 4.0 26.3 21.1 40.7 3.8 15.0 10.8 12.1 47.1 6.0 26.9 15.1 9.7 MAGEB2 "CT3.2, DAM6, MAGE-XP-2, MGC26438" ENSG00000099399 "MAGE family member B2" O15479 X 30215563-30220089 "Predicted intracellular proteins" "Ubl conjugation pathway" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 60 "testis: 29.1" "Group enriched" "Detected in some" 4 "Spermatocytes: 24.7;Spermatogonia: 95.8" "Cancer enriched" "Detected in many" 7 "testis cancer: 33.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HL-60: 92.4;K-562: 66.9;Karpas-707: 77.0;U-2 OS: 89.9;U-266/70: 149.7;U-266/84: 168.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA065224, HPA074544, HPA075519" Enhanced Approved Cytosol NA Yes "Cluster 36: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Cytosol "HPA065224: AB_2685437, HPA074544: AB_2732258, HPA075519: AB_2732294" "unprognostic (4.52e-1)" "unprognostic (2.55e-2)" "unprognostic (6.39e-2)" "unprognostic (5.02e-1)" "unprognostic (6.57e-2)" "unprognostic (1.79e-2)" "unprognostic (1.00e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 6.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 92.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 66.9 77.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.2 0.0 0.5 0.0 14.8 0.2 0.0 89.9 0.3 0.3 149.7 168.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 3.1 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 24.7 95.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 MARCKSL1 "F52, MacMARCKS, MLP, MLP1" ENSG00000175130 "MARCKS like 1" P49006 1 32333839-32336233 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 712.7" "Cell type enhanced" "Detected in many" "monocytes: 941.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 8 "eosinophil: 252.7" "Lineage enriched" "Detected in all" 8 "granulocytes: 252.7" "Cell line enhanced" "Detected in many" "AF22: 1016.3;NTERA-2: 984.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020787, HPA030528" Enhanced Supported "Nucleoplasm,Actin filaments,Cytosol" NA Yes 170000 "Cluster 52: Eosinophils - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 5: NTERA-2 - Transcription" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "Nucleoplasm, Actin filaments" "CAB020787: , HPA030528: AB_2673514" "unprognostic (8.08e-2)" "unprognostic (1.28e-1)" "unprognostic (1.11e-1)" "unprognostic (1.04e-2)" "unprognostic (1.38e-1)" "unprognostic (3.16e-3)" "prognostic unfavorable (1.78e-6)" "unprognostic (3.65e-1)" "unprognostic (1.72e-1)" "unprognostic (8.41e-3)" "unprognostic (2.91e-1)" "unprognostic (1.76e-2)" "prognostic unfavorable (1.20e-4)" "unprognostic (1.50e-1)" "unprognostic (8.16e-3)" "unprognostic (1.08e-1)" "unprognostic (3.22e-2)" 63.4 59.9 363.5 82.1 510.3 50.1 102.9 540.1 438.2 81.2 206.4 108.1 61.8 93.4 155.8 15.1 72.2 97.2 55.0 343.0 408.0 51.1 38.7 40.0 176.0 631.5 504.7 358.0 23.7 6.5 22.9 42.9 534.9 84.7 116.5 37.9 75.9 49.9 8.7 28.3 56.1 42.7 467.9 63.1 132.8 139.2 466.4 166.0 110.3 11.0 199.5 77.8 27.1 712.7 82.9 73.3 1016.3 418.6 22.5 8.3 181.0 34.0 21.2 99.9 66.0 176.0 59.9 185.7 124.4 23.2 0.3 43.0 333.1 3.8 73.3 4.5 246.5 10.0 27.0 392.4 68.7 48.8 0.9 114.8 13.7 75.0 2.1 154.2 295.0 312.6 291.5 2.2 135.7 197.5 613.5 205.9 984.3 267.4 168.1 754.8 109.4 87.7 152.1 163.1 629.0 597.8 178.8 194.2 587.8 411.9 135.4 85.8 87.8 41.8 241.3 3.9 66.1 27.8 2.3 489.8 4.7 73.6 225.7 3.1 4.0 252.7 3.8 23.1 1.4 20.0 7.4 4.9 6.6 27.7 15.3 6.4 18.2 1.1 30.3 9.0 4.8 4.9 363.5 510.3 540.1 438.2 343.0 408.0 631.5 504.7 534.9 467.9 466.4 712.7 242.5 0.0 1.3 27.1 191.1 93.7 114.7 43.5 40.5 27.7 465.7 385.8 8.5 178.7 68.8 60.7 6.2 16.1 110.1 194.1 82.2 389.7 37.4 68.7 190.3 326.9 746.2 74.4 4.2 307.2 116.4 124.3 246.2 115.2 22.3 378.6 462.3 5.3 21.2 10.1 21.9 514.2 236.0 61.0 365.3 66.7 613.3 82.0 300.6 9.4 941.4 464.3 46.4 93.0 428.3 751.6 292.8 641.3 39.5 418.8 30.2 9.8 15.6 14.8 131.5 40.3 210.0 14.8 102.7 22.5 83.1 13.4 89.8 172.0 447.1 586.9 MASTL "FLJ14813, Gwl, THC2" ENSG00000120539 "Microtubule associated serine/threonine kinase like" Q96GX5 10 27154824-27187953 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 24.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027175, HPA054273" Approved Enhanced Nucleoplasm NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA027175: AB_1853591, HPA054273: AB_2682433" "unprognostic (4.10e-2)" "unprognostic (6.89e-2)" "unprognostic (1.22e-2)" "unprognostic (3.14e-3)" "unprognostic (3.67e-1)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.52e-6)" "unprognostic (2.19e-2)" "unprognostic (4.00e-2)" "unprognostic (4.05e-2)" "prognostic unfavorable (4.81e-5)" "unprognostic (3.78e-2)" "prognostic unfavorable (1.71e-6)" "unprognostic (1.55e-3)" "unprognostic (2.27e-1)" "unprognostic (2.66e-1)" "unprognostic (1.79e-1)" 5.0 3.9 1.7 6.2 1.9 18.7 5.3 2.3 2.3 3.8 2.1 4.1 4.4 3.9 4.5 5.9 3.0 3.9 2.5 1.9 2.0 3.9 4.9 4.0 8.9 2.0 2.0 3.4 3.3 6.0 3.1 6.5 2.1 3.1 5.2 2.7 4.1 3.0 2.3 6.0 4.3 4.5 1.6 4.6 4.7 6.5 2.0 10.4 4.7 2.2 7.1 4.5 4.3 2.3 29.4 22.0 43.8 15.5 6.2 9.1 25.4 43.3 18.0 68.4 83.8 26.7 27.2 22.4 16.1 18.4 33.5 26.8 27.9 16.0 48.2 20.2 26.5 26.9 14.5 15.5 3.8 10.4 19.8 5.6 7.5 41.6 7.9 9.0 14.7 18.2 21.1 49.9 41.5 17.9 34.8 11.2 32.0 15.9 8.9 22.2 71.9 18.9 17.4 10.6 19.2 26.8 26.0 17.6 19.1 28.1 17.2 21.4 12.6 17.0 36.3 44.0 37.4 5.9 10.3 34.7 18.3 31.1 14.8 0.2 1.8 1.7 0.7 1.7 1.1 1.1 0.9 0.7 1.0 1.6 0.9 0.8 2.3 1.0 1.8 1.1 1.6 0.8 1.7 1.9 2.3 2.3 1.9 2.0 2.0 2.0 2.1 1.6 2.0 2.3 4.3 6.4 7.8 2.6 7.4 11.0 4.9 4.4 4.0 1.7 4.2 4.8 3.0 2.8 7.0 1.8 0.0 8.6 10.1 7.0 0.0 4.0 3.0 9.7 5.3 4.6 4.2 7.8 4.3 2.5 24.9 7.3 6.1 17.9 12.7 6.9 2.5 2.5 5.8 3.3 4.3 3.7 4.1 7.8 19.3 1.7 3.1 11.3 0.0 3.7 5.1 1.8 3.1 3.5 4.9 4.4 2.9 2.6 7.1 5.0 2.8 1.9 4.0 1.0 0.0 3.8 5.3 14.9 14.1 10.9 9.9 6.2 11.6 5.4 4.5 6.6 MB21D2 C3orf59 ENSG00000180611 "Mab-21 domain containing 2" Q8IYB1 3 192796815-192917856 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 63.8;Inhibitory neurons: 53.0;Langerhans cells: 85.0;Oligodendrocyte precursor cells: 68.9;Syncytiotrophoblasts: 110.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 4.2;T-reg: 3.9" "Lineage enriched" "Detected in single" 9 "T-cells: 4.2" "Cell line enhanced" "Detected in many" "HDLM-2: 114.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044026 Approved Approved Cytosol NA Yes "Cluster 13: T-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 44: HDLM-2 - Immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA044026: AB_10962840" "unprognostic (3.52e-2)" "unprognostic (1.02e-1)" "unprognostic (3.06e-1)" "prognostic unfavorable (3.74e-5)" "unprognostic (2.42e-2)" "prognostic unfavorable (9.94e-4)" "unprognostic (2.76e-2)" "unprognostic (3.50e-2)" "unprognostic (1.53e-1)" "unprognostic (2.46e-1)" "unprognostic (2.84e-2)" "unprognostic (1.57e-1)" "unprognostic (1.30e-3)" "unprognostic (5.94e-3)" "unprognostic (1.95e-1)" "unprognostic (3.80e-2)" "unprognostic (3.28e-2)" 3.7 4.2 2.5 3.2 2.8 1.3 3.4 3.3 3.1 2.8 1.6 3.0 8.8 5.1 1.9 2.0 3.6 4.7 4.0 2.8 2.3 4.2 1.5 3.6 1.2 2.1 2.0 4.1 1.9 2.3 3.5 13.3 1.8 1.9 2.9 2.0 1.5 1.9 2.7 4.7 9.3 5.6 1.5 2.2 3.5 7.1 1.9 1.4 1.7 1.6 1.7 8.8 2.4 2.3 26.6 3.7 6.3 19.0 3.9 5.8 11.2 18.8 17.5 33.4 19.9 17.0 4.2 0.0 11.0 46.6 13.8 11.5 14.6 4.8 36.2 114.8 8.1 3.3 1.8 2.0 7.4 0.4 1.6 7.6 7.4 9.4 5.8 2.7 6.6 3.3 0.2 1.5 5.8 19.8 0.3 0.0 13.1 14.4 45.9 0.6 10.5 5.6 7.8 15.1 9.8 5.0 4.1 12.8 1.9 12.9 19.9 0.4 2.1 6.3 18.4 11.1 36.3 48.1 41.0 0.0 4.4 4.0 8.6 0.0 0.2 0.0 0.2 0.3 1.9 0.1 4.2 1.0 0.4 0.0 2.6 0.7 0.0 0.0 0.0 0.0 3.9 0.9 2.5 2.8 3.3 3.1 2.8 2.3 2.1 2.0 1.8 1.5 1.9 2.3 2.9 6.4 0.5 16.6 1.2 9.2 0.9 2.0 1.2 10.9 4.6 3.2 1.8 1.5 3.2 0.0 2.1 63.8 0.3 2.4 0.0 6.5 0.2 12.4 2.0 7.7 10.2 0.0 28.6 0.2 9.5 5.9 1.5 15.9 0.0 5.8 9.7 0.2 5.6 8.4 53.0 2.8 4.1 3.8 85.0 1.4 3.1 10.4 14.2 17.8 13.4 1.1 0.0 68.9 30.6 2.2 6.1 6.0 4.2 0.8 15.4 9.6 2.8 1.3 13.1 3.3 4.5 1.8 16.5 1.8 8.7 110.4 3.3 5.4 3.7 2.6 MCM10 "CNA43, DNA43, PRO2249" ENSG00000065328 "Minichromosome maintenance 10 replication initiation factor" Q7L590 10 13161558-13211110 "Predicted intracellular proteins" "DNA damage, DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 9.2;lymphoid tissue: 8.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 11.8;Erythroid cells: 23.5;Extravillous trophoblasts: 20.9;Plasma cells: 15.3;Spermatocytes: 15.8;Spermatogonia: 12.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045899, HPA071952" Approved Supported Nucleoplasm,Nucleoli Yes Yes "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli" "HPA045899: AB_10960529, HPA071952: AB_2686477" "unprognostic (9.76e-3)" "unprognostic (1.60e-1)" "unprognostic (2.31e-1)" "unprognostic (2.29e-3)" "unprognostic (1.41e-1)" "unprognostic (6.58e-3)" "unprognostic (1.78e-8)" "unprognostic (2.42e-3)" "unprognostic (3.51e-2)" "unprognostic (6.26e-2)" "unprognostic (2.78e-4)" "unprognostic (7.81e-2)" "unprognostic (0.00e+0)" "unprognostic (8.87e-2)" "unprognostic (1.29e-1)" "unprognostic (9.73e-2)" "unprognostic (1.05e-1)" 1.2 0.1 0.0 3.3 0.1 9.2 0.8 0.1 0.2 0.4 0.1 1.7 1.5 0.4 0.1 1.9 0.2 0.2 0.1 0.0 0.0 0.1 0.7 0.3 4.8 0.0 0.1 0.2 0.1 0.2 0.1 2.1 0.1 0.1 2.2 0.1 0.3 0.0 0.5 1.1 1.2 0.8 0.0 1.0 0.8 1.5 0.2 8.1 0.3 0.1 4.5 0.6 0.6 0.1 38.0 42.0 48.6 36.9 1.6 2.9 21.2 38.7 5.9 42.7 44.0 41.3 26.4 56.7 17.1 9.9 15.7 43.3 69.0 22.8 39.2 29.7 32.9 70.9 17.6 27.7 0.0 36.6 30.8 0.6 0.8 43.3 4.0 3.5 14.0 45.0 85.2 37.6 23.4 34.0 87.7 15.7 28.9 36.3 10.3 68.3 43.0 34.6 9.8 13.7 9.7 36.6 31.3 22.0 5.9 25.2 27.7 24.9 8.6 27.0 50.3 41.0 42.4 11.7 49.0 74.3 17.2 39.6 21.5 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.9 0.3 0.1 0.1 0.7 0.4 0.1 0.1 0.0 0.4 0.4 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 1.7 0.0 0.0 0.0 1.8 1.7 0.4 0.8 0.0 0.0 0.8 0.5 2.4 0.0 0.8 0.0 0.0 11.8 0.8 2.4 0.0 0.4 1.0 0.3 1.2 1.4 0.0 23.5 0.4 0.2 20.9 1.8 1.1 1.0 0.0 7.2 0.0 0.2 5.3 0.0 0.4 1.2 2.0 0.6 0.4 1.3 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.1 0.4 15.3 0.2 0.2 0.0 0.0 0.0 0.0 0.4 6.4 15.8 12.9 3.6 0.4 3.4 1.2 0.8 3.1 0.4 MCM2 "BM28, CCNL1, cdc19, CDCL1, D3S3194, DFNA70, KIAA0030" ENSG00000073111 "Minichromosome maintenance complex component 2" P49736 3 127598410-127622436 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 67.7;lymphoid tissue: 37.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 63.3;Erythroid cells: 65.6;Extravillous trophoblasts: 28.8;Spermatogonia: 25.9;Syncytiotrophoblasts: 33.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "CAB000303, HPA031450, HPA031495, HPA031496" Enhanced Enhanced Nucleoplasm Yes Yes 120000 "Cluster 43: B-cells - Humoral immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB000303: AB_322519, HPA031450: , HPA031495: AB_2673904, HPA031496: AB_2673905" "unprognostic (2.43e-1)" "prognostic favorable (4.66e-4)" "unprognostic (4.44e-2)" "unprognostic (3.12e-3)" "unprognostic (1.68e-1)" "unprognostic (2.25e-2)" "prognostic unfavorable (1.51e-7)" "unprognostic (8.43e-3)" "unprognostic (1.92e-2)" "unprognostic (1.79e-1)" "unprognostic (1.41e-3)" "unprognostic (1.21e-2)" "unprognostic (1.16e-2)" "unprognostic (8.16e-3)" "unprognostic (1.56e-1)" "unprognostic (3.29e-2)" "unprognostic (2.82e-1)" 3.1 3.4 2.0 16.4 1.9 67.7 6.2 2.5 1.9 5.3 0.6 9.2 8.1 5.0 2.4 11.0 7.6 2.5 6.4 1.9 1.8 3.4 6.3 3.4 26.8 2.3 1.9 6.4 3.0 3.7 2.4 17.0 2.6 5.0 10.2 3.5 4.7 2.8 9.4 10.6 8.6 5.3 2.0 9.6 5.7 12.3 2.0 37.6 4.8 5.8 26.0 4.2 5.4 2.4 133.6 110.3 122.4 102.1 7.0 14.4 110.5 65.2 42.3 129.9 146.9 177.7 84.7 136.0 65.2 32.3 113.6 105.6 204.8 76.1 79.1 127.2 127.1 227.4 134.8 131.1 4.4 214.3 102.4 8.2 8.4 86.1 13.1 15.3 40.6 160.7 116.0 123.7 47.4 169.0 229.0 156.2 172.5 108.3 90.7 242.4 165.1 203.3 26.9 97.9 143.0 106.8 175.8 48.9 16.7 45.7 111.9 165.3 20.3 104.2 87.9 128.4 91.7 127.1 163.5 362.6 73.2 159.7 41.0 0.0 0.6 0.3 4.4 1.4 5.5 9.7 3.9 5.4 2.9 8.1 3.6 4.7 0.9 6.5 0.4 3.7 11.2 3.5 2.0 1.9 2.5 1.9 1.9 1.8 2.3 1.9 2.6 2.0 2.0 2.4 1.2 3.2 2.0 0.7 8.5 4.6 2.6 4.6 2.2 2.5 4.1 5.3 8.3 0.0 3.9 0.0 0.0 63.3 1.8 4.8 0.0 5.3 0.9 5.2 3.5 2.9 3.6 65.6 0.3 1.9 28.8 4.2 6.6 4.8 1.3 18.8 1.4 1.7 18.2 0.0 0.4 8.2 0.0 1.6 3.2 0.7 1.8 2.7 1.8 0.0 9.2 2.1 0.0 0.0 0.7 2.1 1.7 1.5 20.5 0.8 1.1 0.8 7.4 2.1 0.0 2.6 4.1 8.1 25.9 7.1 3.0 33.5 6.3 3.8 13.8 2.3 MCM3 ENSG00000112118 "Minichromosome maintenance complex component 3" P25205 6 52264014-52284881 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 122.7;Erythroid cells: 92.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002162, HPA004789, HPA004790" Supported Supported Nucleoplasm NA Yes 150000 "Cluster 35: T-regs - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB002162: AB_564115, HPA004789: AB_1079336, HPA004790: AB_1079335" "unprognostic (9.14e-2)" "prognostic favorable (1.89e-4)" "unprognostic (2.37e-1)" "unprognostic (1.53e-2)" "unprognostic (2.14e-1)" "unprognostic (5.48e-3)" "prognostic unfavorable (1.40e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (4.40e-5)" "unprognostic (1.01e-3)" "unprognostic (2.96e-2)" "unprognostic (1.15e-1)" "unprognostic (8.35e-2)" "unprognostic (1.16e-2)" "unprognostic (1.00e-1)" "prognostic favorable (3.13e-5)" "unprognostic (1.34e-2)" 24.3 15.9 12.8 41.5 13.6 55.5 29.1 13.7 13.7 27.5 13.4 32.9 19.6 30.8 23.8 33.4 29.2 16.4 25.4 11.9 12.7 27.5 18.8 21.4 68.8 14.1 13.6 31.9 17.0 28.9 10.8 40.0 14.1 19.7 39.3 19.3 19.2 30.7 16.0 32.2 29.3 37.0 14.5 31.3 24.1 21.1 14.0 81.1 18.3 17.7 78.5 28.1 24.5 13.9 187.9 121.7 208.0 196.9 43.9 39.4 136.1 135.8 103.7 226.6 230.3 251.6 99.2 202.8 132.5 79.7 147.8 145.4 277.4 165.9 226.9 230.0 261.4 383.6 233.2 358.2 11.8 381.7 150.8 23.7 38.1 166.6 46.2 55.6 117.3 240.4 318.1 452.9 118.3 123.8 386.9 293.5 173.1 369.8 84.8 338.3 317.0 271.2 101.1 195.8 210.3 160.5 142.2 81.1 125.3 289.4 159.7 266.9 60.5 153.5 163.6 160.8 206.4 132.9 163.5 356.4 132.2 323.8 184.0 30.5 18.3 27.3 50.0 31.3 42.8 47.7 49.9 50.3 30.0 41.2 47.6 51.2 2.6 55.0 18.3 19.0 71.6 46.9 12.8 13.6 13.7 13.7 11.9 12.7 14.1 13.6 14.1 14.5 14.0 13.9 24.3 22.4 12.3 3.3 26.4 19.2 20.0 24.9 12.5 16.1 14.1 17.1 19.9 7.2 19.2 22.0 4.2 122.7 18.6 10.9 13.7 30.9 1.1 9.6 16.7 30.9 7.3 92.6 2.5 20.2 63.6 22.3 15.8 15.1 37.4 48.3 15.0 10.5 36.0 0.0 2.1 20.4 8.2 10.1 7.5 3.6 27.1 12.1 7.2 8.4 12.5 17.8 34.0 2.5 6.1 17.3 10.5 21.1 37.6 10.9 7.3 7.5 17.0 16.0 6.6 16.8 27.9 22.5 64.0 24.5 10.1 27.4 26.0 19.0 37.1 13.9 MCM4 "CDC21, CDC54, hCdc21, MGC33310, P1-Cdc21" ENSG00000104738 "Minichromosome maintenance complex component 4" P33991 8 47960185-47978160 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 63.2" "Cell type enhanced" "Detected in many" "Early spermatids: 153.2;Erythroid cells: 60.8;Late spermatids: 77.9;Spermatocytes: 65.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004497, HPA004873, HPA031052" Enhanced Enhanced Nucleoplasm NA Yes 140000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB004497: AB_627916, HPA004873: AB_1079337, HPA031052: AB_2673712" "unprognostic (4.55e-2)" "unprognostic (3.16e-3)" "prognostic favorable (2.19e-4)" "prognostic unfavorable (2.84e-5)" "unprognostic (7.71e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (1.23e-4)" "unprognostic (1.12e-3)" "prognostic unfavorable (1.15e-4)" "unprognostic (2.65e-2)" "prognostic unfavorable (2.38e-4)" "unprognostic (5.16e-2)" "prognostic unfavorable (2.61e-4)" "unprognostic (3.53e-2)" "unprognostic (2.90e-1)" "unprognostic (1.70e-2)" "unprognostic (1.40e-1)" 6.5 8.8 4.8 21.7 4.8 63.2 16.0 5.7 5.2 7.7 1.8 17.7 13.3 6.9 4.6 22.4 9.7 5.6 14.5 5.2 3.5 8.2 9.2 6.3 38.7 3.6 4.2 7.1 5.5 7.7 4.1 18.3 3.9 5.6 21.3 12.3 8.8 4.9 13.4 24.2 16.7 9.2 4.2 8.1 10.6 41.6 4.8 47.0 6.5 15.8 41.8 11.8 10.9 5.2 184.0 139.6 188.1 83.2 20.7 36.6 102.8 122.6 99.8 178.5 190.3 156.6 181.1 229.8 70.3 72.1 119.2 143.2 278.7 128.2 199.8 64.2 190.4 371.8 133.3 169.2 5.4 189.7 82.0 20.3 24.1 147.8 54.3 28.6 72.0 136.8 216.2 167.0 129.9 155.6 435.5 141.5 241.2 246.5 54.2 266.6 159.6 139.2 64.9 168.1 209.0 97.8 325.6 133.6 46.3 117.7 154.9 110.5 45.1 138.1 125.4 144.5 131.9 54.7 104.6 347.2 114.8 185.7 131.5 2.3 1.8 1.1 4.0 3.1 2.0 3.9 3.8 5.4 3.9 1.6 3.3 2.7 0.1 4.1 3.5 1.5 10.2 3.6 4.8 4.8 5.7 5.2 5.2 3.5 3.6 4.2 3.9 4.2 4.8 5.2 3.3 0.0 6.3 3.3 6.5 21.7 11.1 9.0 13.6 12.2 9.0 7.7 25.1 1.5 8.4 5.5 10.4 36.7 5.8 12.1 3.9 8.0 153.2 11.0 7.9 6.7 6.7 60.8 5.0 6.0 40.2 10.6 11.2 13.4 1.3 24.9 2.2 3.2 12.3 16.8 5.7 13.9 4.1 2.9 6.5 77.9 5.3 7.9 3.6 1.9 2.4 7.0 3.1 4.0 2.9 4.5 4.8 3.0 22.3 7.7 5.6 3.0 13.1 16.7 0.0 9.5 11.4 65.8 39.9 19.1 19.0 29.8 9.0 11.7 26.2 9.7 MCM5 CDC46 ENSG00000100297 "Minichromosome maintenance complex component 5" P33992 22 35400134-35425431 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 138.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 147.8;Erythroid cells: 96.6;monocytes: 137.7;Syncytiotrophoblasts: 82.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000101, HPA000845, HPA052880" Enhanced Enhanced Nucleoplasm Yes Yes 44000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB000101: AB_2235163, HPA000845: AB_1079338, HPA052880: AB_2681979" "unprognostic (6.71e-2)" "prognostic favorable (2.81e-6)" "unprognostic (5.29e-3)" "unprognostic (7.94e-2)" "unprognostic (1.83e-2)" "unprognostic (1.46e-2)" "prognostic unfavorable (1.78e-4)" "prognostic unfavorable (3.95e-4)" "unprognostic (1.29e-1)" "unprognostic (3.34e-2)" "unprognostic (1.37e-1)" "unprognostic (8.07e-2)" "prognostic unfavorable (3.58e-5)" "unprognostic (3.26e-2)" "unprognostic (1.01e-1)" "unprognostic (1.77e-3)" "unprognostic (1.53e-1)" 15.2 7.1 5.8 49.1 10.4 138.7 14.4 8.3 7.4 14.5 5.8 20.2 19.6 16.3 3.3 25.1 13.7 9.6 8.9 5.8 7.0 9.1 14.9 14.8 70.1 10.3 7.7 25.6 12.6 10.3 5.3 25.2 9.6 10.2 16.7 2.3 13.9 9.6 13.3 17.6 28.3 12.2 8.1 47.3 17.9 20.6 9.0 58.9 12.1 8.0 53.6 12.7 15.6 12.3 213.0 147.5 115.7 118.8 11.0 22.2 100.6 138.1 71.2 199.4 188.3 98.9 102.4 137.9 78.8 70.5 83.6 103.8 116.0 108.3 64.4 112.7 212.6 198.3 141.5 203.7 3.9 414.0 172.4 12.3 9.7 120.0 32.4 18.4 88.7 124.5 124.0 201.2 76.9 172.7 341.8 137.9 154.9 143.4 86.7 379.6 164.8 173.0 39.4 120.1 88.2 94.8 188.3 75.4 41.8 60.9 78.8 155.6 54.1 201.3 153.1 127.2 145.4 111.9 150.2 265.2 130.9 153.5 157.6 66.5 59.8 43.4 49.5 69.6 35.8 127.5 43.1 53.1 77.8 106.1 34.0 39.0 28.4 65.5 81.2 88.8 96.6 77.1 5.8 10.4 8.3 7.4 5.8 7.0 10.3 7.7 9.6 8.1 9.0 12.3 8.1 6.4 7.3 1.3 49.5 10.6 13.6 12.1 8.6 1.5 9.2 10.8 3.5 8.6 6.0 7.3 0.0 147.8 30.4 12.0 5.9 19.8 2.8 6.2 4.1 11.8 3.5 96.6 0.3 12.7 77.1 11.2 18.8 9.0 15.2 65.7 13.2 5.3 53.1 1.7 0.4 16.6 4.1 24.0 29.4 5.1 10.8 28.4 7.2 7.5 137.7 5.7 13.4 3.0 6.0 11.0 8.6 6.0 49.3 4.0 6.5 5.7 4.8 3.7 19.7 8.8 14.5 16.1 58.8 14.9 6.3 82.2 19.4 8.5 34.6 9.8 MCM6 Mis5 ENSG00000076003 "Minichromosome maintenance complex component 6" Q14566 2 135839626-135876443 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 48.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 40.1;Erythroid cells: 50.5;Spermatogonia: 40.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004818, CAB009577" Enhanced Enhanced Nucleoplasm NA Yes 33000 "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB009577: AB_2266309, HPA004818: AB_1079339" "unprognostic (6.73e-2)" "unprognostic (6.68e-3)" "unprognostic (1.22e-3)" "unprognostic (3.60e-3)" "unprognostic (8.98e-2)" "unprognostic (4.34e-2)" "prognostic unfavorable (5.70e-7)" "unprognostic (1.71e-2)" "prognostic unfavorable (1.09e-5)" "unprognostic (2.36e-2)" "unprognostic (1.36e-2)" "unprognostic (3.53e-2)" "prognostic unfavorable (8.29e-12)" "unprognostic (2.84e-1)" "unprognostic (9.02e-2)" "unprognostic (7.42e-2)" "unprognostic (1.68e-1)" 10.0 5.3 4.7 20.7 5.1 35.6 11.6 6.3 6.4 10.2 3.5 12.8 11.7 10.0 5.1 11.1 7.9 6.8 5.3 5.0 5.1 6.4 9.5 7.8 34.4 4.4 4.6 11.3 3.9 4.6 3.0 12.6 4.7 6.9 15.6 3.2 6.0 8.3 8.1 10.5 13.2 11.8 4.8 9.9 8.2 14.6 5.4 48.5 4.5 7.6 38.0 9.6 8.9 5.5 104.4 62.8 133.8 85.7 28.2 36.5 52.3 73.9 55.8 84.3 93.0 129.3 77.7 181.0 52.9 54.0 36.9 60.4 136.7 67.6 89.5 93.6 94.4 179.9 85.0 40.9 13.1 218.4 76.9 21.7 8.6 61.7 18.9 16.8 58.1 139.8 130.8 147.9 62.6 106.3 268.6 159.6 120.9 91.3 62.1 131.1 159.9 165.7 42.3 90.3 83.7 71.3 97.6 45.9 47.0 95.2 53.1 135.4 29.0 58.3 48.0 63.4 56.8 87.8 153.7 234.2 81.4 163.5 70.9 9.2 1.6 1.1 8.1 4.7 7.6 6.1 11.1 9.9 5.2 4.7 9.9 12.4 0.9 9.1 4.5 10.6 16.1 6.3 4.7 5.1 6.3 6.4 5.0 5.1 4.4 4.6 4.7 4.8 5.4 5.5 6.4 0.0 2.7 3.9 10.3 6.6 4.1 5.4 7.4 3.3 4.2 5.8 4.6 2.8 5.4 3.7 0.0 40.1 28.2 3.0 0.0 7.2 3.2 2.5 8.9 8.3 2.4 50.5 3.5 6.6 28.0 13.3 9.7 7.1 9.5 27.2 8.9 3.0 24.4 3.3 3.4 11.7 0.0 4.7 3.5 2.1 9.3 9.6 5.4 3.7 3.2 2.4 4.1 2.0 2.8 3.9 4.9 17.0 27.6 1.6 2.4 0.9 3.0 0.5 0.0 7.2 10.0 26.6 40.4 10.2 4.1 10.7 22.0 9.6 15.4 2.7 MCM7 "CDC47, MCM2, PPP1R104" ENSG00000166508 "Minichromosome maintenance complex component 7" P33993 7 100092728-100101940 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 180.8;lymphoid tissue: 156.4" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 132.9;Erythroid cells: 173.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002163, HPA003898, CAB016312" Enhanced Enhanced Nucleoplasm NA Yes 150000 "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB002163: AB_564113, CAB016312: AB_627235, HPA003898: AB_1853632" "unprognostic (1.87e-1)" "prognostic favorable (1.28e-4)" "unprognostic (1.36e-1)" "unprognostic (5.20e-2)" "unprognostic (1.94e-1)" "unprognostic (7.03e-2)" "prognostic unfavorable (2.18e-4)" "unprognostic (2.08e-2)" "unprognostic (5.79e-3)" "unprognostic (2.16e-2)" "unprognostic (2.42e-1)" "unprognostic (9.34e-3)" "unprognostic (3.83e-2)" "unprognostic (5.41e-2)" "unprognostic (1.76e-1)" "unprognostic (1.32e-2)" "unprognostic (2.38e-1)" 22.9 14.2 56.4 50.2 61.7 180.8 32.0 51.4 70.4 17.4 45.8 45.3 38.7 29.7 13.1 31.2 25.6 18.2 17.0 48.8 50.5 13.7 26.3 23.0 82.4 58.5 59.8 37.0 24.1 15.1 8.9 35.0 55.1 20.4 50.8 10.6 21.3 22.2 25.7 44.9 41.3 32.3 55.1 29.4 27.4 49.4 55.6 156.4 20.4 28.5 88.5 21.6 11.9 60.8 310.1 359.5 399.9 306.7 28.7 35.5 214.4 195.7 165.5 374.9 407.7 281.9 335.2 469.2 184.6 112.0 321.6 252.5 439.3 241.6 303.9 238.6 498.1 274.7 251.9 248.9 18.9 553.6 226.2 30.1 43.4 306.9 179.6 61.8 154.0 295.1 542.2 444.6 200.8 786.2 940.1 442.9 361.9 295.2 236.4 572.5 517.7 651.6 92.3 221.5 253.4 397.0 264.9 294.3 104.9 217.9 126.2 314.4 81.0 198.1 346.7 379.8 411.1 200.3 311.8 875.0 135.9 463.1 354.3 3.7 4.0 4.3 14.1 7.5 10.9 9.1 10.3 13.2 9.3 15.0 11.2 10.5 1.4 15.9 13.3 11.3 17.2 11.6 56.4 61.7 51.4 70.4 48.8 50.5 58.5 59.8 55.1 55.1 55.6 60.8 23.2 9.6 17.9 6.2 34.5 46.7 28.5 25.7 37.0 9.4 30.8 36.3 9.6 11.5 13.3 3.7 14.6 132.9 32.5 42.3 9.8 28.2 54.7 11.8 16.3 23.8 17.4 173.6 4.0 26.2 102.7 22.8 40.8 19.8 24.1 67.3 10.4 10.3 40.4 6.7 4.0 48.8 18.3 10.4 22.2 32.0 21.1 17.6 19.6 3.7 14.1 11.1 18.6 12.1 11.7 16.7 22.8 15.4 59.8 20.8 19.0 11.5 18.0 12.5 13.1 30.7 46.0 90.0 79.8 41.3 35.4 72.0 29.4 14.9 79.0 22.9 MGAT2 GNT-II ENSG00000168282 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase" Q10469 14 49620799-49623481 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043721, HPA056824" Approved Supported "Golgi apparatus" NA Yes 5100000 "Cluster 44: Non-specific - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA043721: AB_2678636, HPA056824: AB_2683248" "unprognostic (1.20e-2)" "prognostic unfavorable (3.22e-4)" "unprognostic (2.84e-1)" "unprognostic (5.49e-2)" "unprognostic (1.37e-1)" "unprognostic (1.70e-1)" "unprognostic (3.77e-1)" "unprognostic (1.92e-2)" "unprognostic (1.14e-1)" "unprognostic (7.44e-2)" "unprognostic (7.12e-2)" "unprognostic (5.63e-2)" "unprognostic (2.59e-3)" "unprognostic (9.14e-2)" "unprognostic (3.74e-2)" "unprognostic (4.72e-2)" "unprognostic (2.12e-2)" 16.8 17.6 5.9 24.3 5.8 10.3 13.3 6.9 6.8 17.4 9.0 23.6 23.1 12.7 21.7 11.8 11.9 15.2 11.7 5.6 6.7 14.2 40.7 13.8 25.3 6.4 6.3 13.1 23.8 8.2 7.9 22.0 6.6 14.1 21.9 8.2 15.8 13.7 5.0 9.3 22.5 16.0 6.9 20.2 21.0 24.3 7.2 16.4 13.3 5.6 25.1 20.9 8.8 7.3 63.5 30.7 23.2 39.2 53.6 51.7 15.1 68.6 67.7 62.2 55.8 37.5 47.1 63.7 56.9 62.9 36.0 49.5 32.9 39.7 66.7 65.5 29.1 40.7 21.7 37.2 42.3 94.5 91.2 39.8 31.2 36.8 51.8 45.5 75.5 31.4 31.7 170.4 66.3 24.2 32.9 60.1 23.8 22.2 49.1 36.7 67.1 55.6 49.3 36.2 24.0 25.6 49.3 12.9 39.8 22.2 39.1 63.6 78.9 56.1 60.8 41.1 49.6 182.8 94.6 56.7 27.3 46.5 38.6 49.4 38.6 39.3 36.6 34.1 39.3 25.1 33.3 33.1 39.9 15.9 19.3 26.8 11.6 22.3 39.8 47.2 31.6 44.8 5.9 5.8 6.9 6.8 5.6 6.7 6.4 6.3 6.6 6.9 7.2 7.3 17.4 12.8 8.6 2.0 31.7 15.7 25.7 28.8 14.2 13.7 15.5 8.9 0.1 24.3 18.0 11.0 4.2 26.4 46.9 34.6 9.8 31.0 7.9 12.5 20.7 20.8 12.1 19.0 3.0 34.4 40.3 24.3 13.7 11.7 17.1 27.7 27.1 63.0 37.2 18.5 4.3 20.5 40.7 34.5 28.8 6.0 17.4 26.3 21.4 2.8 40.6 16.7 63.8 6.0 4.5 36.5 25.1 22.2 77.1 27.0 26.7 15.2 23.5 15.8 6.6 15.8 34.6 56.4 13.0 15.2 14.1 5.3 31.5 23.2 20.0 25.5 MLF2 NTN4 ENSG00000089693 "Myeloid leukemia factor 2" Q15773 12 6747996-6767475 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010811, HPA010859" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA Yes "Cluster 5: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Plasma membrane, Cytosol" "HPA010811: AB_1079389, HPA010859: AB_1079388" "unprognostic (1.65e-1)" "unprognostic (6.55e-2)" "unprognostic (4.42e-1)" "unprognostic (9.88e-3)" "unprognostic (1.76e-1)" "unprognostic (4.19e-2)" "unprognostic (1.52e-1)" "unprognostic (4.15e-2)" "unprognostic (1.31e-1)" "unprognostic (9.11e-2)" "unprognostic (3.37e-1)" "unprognostic (6.23e-2)" "unprognostic (1.38e-1)" "unprognostic (5.83e-2)" "unprognostic (4.72e-1)" "unprognostic (8.44e-2)" "unprognostic (3.63e-1)" 121.0 199.0 214.6 67.9 225.7 123.8 109.8 206.5 243.7 119.8 215.4 161.8 106.3 148.5 85.2 168.6 120.6 68.1 181.8 234.6 219.0 163.3 298.7 107.0 66.2 208.0 205.8 116.3 111.0 158.2 145.1 79.4 205.8 142.7 74.1 78.2 131.6 96.3 192.8 144.6 117.8 93.0 205.4 101.5 135.9 97.6 211.1 78.3 114.1 129.2 71.2 135.2 117.5 223.6 222.0 354.3 179.1 294.4 159.3 157.9 283.1 216.6 230.6 318.8 286.9 353.8 195.5 163.1 55.0 265.5 228.1 173.5 220.1 295.3 220.0 274.9 239.3 115.3 174.0 200.7 176.0 128.9 143.0 151.7 240.8 255.2 209.8 257.4 140.7 152.0 152.5 61.8 247.8 320.7 165.7 197.9 554.2 236.1 141.2 102.5 160.2 134.0 310.8 247.7 111.2 224.8 188.8 303.6 203.4 385.8 89.8 186.4 133.7 191.4 279.3 213.5 299.9 80.9 98.2 208.9 259.0 102.2 231.2 259.6 120.3 461.0 82.0 109.9 80.9 85.6 63.7 78.3 134.0 97.6 66.2 75.3 528.0 76.6 129.2 231.6 69.7 115.3 214.6 225.7 206.5 243.7 234.6 219.0 208.0 205.8 205.8 205.4 211.1 223.6 106.3 38.5 30.9 19.2 77.9 136.5 149.3 230.2 261.2 110.2 157.7 156.3 71.9 92.9 108.7 110.3 41.7 264.3 92.4 120.6 279.7 169.9 12.1 64.6 70.7 86.4 100.7 74.9 36.2 125.9 213.7 100.6 91.7 74.9 84.9 84.1 71.0 168.6 147.7 80.8 32.7 138.6 197.4 57.8 70.6 13.3 114.0 78.9 103.2 13.1 138.9 142.7 39.1 19.1 23.5 153.8 124.7 107.2 108.2 202.6 219.6 324.7 58.6 63.5 52.6 77.1 131.8 96.6 80.8 193.1 125.6 427.6 70.2 138.3 145.0 174.6 MMS22L "C6orf167, dJ39B17.2" ENSG00000146263 "MMS22 like, DNA repair protein" Q6ZRQ5 6 97142161-97283217 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 67.8;Oligodendrocytes: 52.3;Spermatocytes: 56.9;Spermatogonia: 45.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA067042 Supported Nucleoplasm NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA067042: AB_2685768" "unprognostic (3.61e-2)" "unprognostic (2.80e-1)" "unprognostic (2.26e-2)" "unprognostic (1.97e-3)" "unprognostic (1.70e-1)" "unprognostic (1.52e-1)" "unprognostic (1.00e-5)" "unprognostic (9.63e-2)" "unprognostic (5.81e-3)" "unprognostic (8.21e-3)" "unprognostic (9.39e-2)" "unprognostic (6.58e-2)" "unprognostic (1.34e-6)" "unprognostic (3.48e-2)" "unprognostic (2.00e-1)" "unprognostic (1.66e-1)" "unprognostic (1.29e-1)" 1.1 1.1 0.7 2.0 1.8 7.0 2.3 1.3 1.2 1.6 0.7 1.6 1.2 1.5 0.5 1.7 1.4 1.0 0.7 0.7 1.0 0.8 0.9 1.1 3.4 2.1 1.4 1.4 1.3 1.4 0.5 2.0 1.8 1.3 2.3 2.4 1.0 0.8 0.6 2.9 1.6 1.5 1.2 1.4 1.1 6.8 1.5 5.2 1.1 0.5 3.4 1.3 1.1 2.4 7.5 8.2 13.5 14.8 2.2 4.0 10.6 15.0 6.9 13.8 20.1 11.4 8.6 16.4 9.0 5.7 16.0 13.4 17.1 8.3 27.4 14.1 12.7 16.7 11.3 7.2 1.3 25.8 11.3 2.2 4.3 19.5 9.0 2.8 6.0 15.2 23.1 25.6 13.1 8.9 9.5 10.4 5.2 12.1 6.1 15.8 12.8 5.8 5.9 9.7 7.7 6.6 9.8 4.9 4.0 7.6 7.6 15.7 4.5 14.0 13.3 11.8 20.8 3.2 10.3 18.3 8.0 16.0 15.7 0.5 0.4 0.9 0.6 0.7 1.0 0.5 0.9 1.0 1.1 0.7 0.8 1.1 0.4 0.6 1.6 1.2 0.9 0.4 0.7 1.8 1.3 1.2 0.7 1.0 2.1 1.4 1.8 1.2 1.5 2.4 5.9 3.2 8.6 16.6 9.7 9.2 5.8 4.0 4.0 11.6 6.1 6.2 4.2 5.7 6.9 3.7 41.7 12.5 14.6 3.3 1.9 2.9 67.8 4.4 6.1 6.5 1.2 26.3 11.3 4.1 11.2 6.1 7.7 2.8 7.6 24.0 10.8 3.1 6.4 3.3 7.7 8.4 8.2 7.5 6.0 17.2 9.9 6.8 7.2 36.5 6.4 6.1 6.2 22.6 52.3 3.0 2.0 5.7 13.1 2.9 5.4 0.8 6.1 31.9 6.6 7.9 5.1 56.9 45.8 7.1 8.2 3.6 9.6 5.2 10.3 3.0 MORF4L2 "KIAA0026, MRGX" ENSG00000123562 "Mortality factor 4 like 2" Q15014 X 103675496-103688158 "Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Growth regulation, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 1214.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031872, HPA054102" Supported Enhanced Nucleoplasm NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 68: Epididymis - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA031872: AB_2674081, HPA054102: AB_2682379" "prognostic unfavorable (9.83e-4)" "unprognostic (2.04e-1)" "unprognostic (1.81e-1)" "unprognostic (7.14e-3)" "unprognostic (2.59e-1)" "prognostic unfavorable (4.29e-5)" "unprognostic (5.27e-2)" "unprognostic (6.34e-3)" "unprognostic (2.41e-1)" "unprognostic (4.49e-3)" "unprognostic (1.88e-1)" "unprognostic (1.10e-2)" "prognostic unfavorable (7.86e-7)" "unprognostic (8.54e-2)" "unprognostic (2.65e-2)" "unprognostic (1.78e-1)" "unprognostic (4.05e-1)" 142.9 184.7 173.9 97.3 180.9 99.0 179.3 156.9 261.5 249.3 183.1 113.4 89.5 262.5 217.7 121.1 209.8 129.2 138.4 180.9 210.1 130.2 204.9 132.6 72.5 170.8 180.3 358.2 137.2 137.2 198.8 242.6 191.2 161.9 140.1 94.1 121.2 191.6 175.6 103.9 99.6 328.5 166.9 90.6 118.0 90.1 183.6 79.3 159.2 130.7 109.6 172.1 143.1 179.1 404.7 257.2 372.6 167.3 541.7 388.2 486.6 533.0 479.4 437.1 462.2 259.6 369.5 289.1 401.4 533.5 522.0 272.0 477.1 406.9 535.6 120.9 219.0 157.5 413.9 308.9 602.7 212.2 141.6 449.6 351.2 380.8 489.6 389.2 478.9 142.2 249.5 383.0 551.5 403.7 188.0 207.6 355.5 512.0 322.3 186.9 340.9 292.1 456.5 221.4 347.3 275.5 425.7 310.1 418.5 385.2 203.3 198.1 433.8 263.2 171.2 459.1 289.3 179.3 221.3 241.2 472.1 420.1 403.8 54.1 40.9 32.9 41.2 44.0 46.9 37.0 38.9 38.2 41.8 32.3 41.7 37.0 16.1 46.0 47.3 70.2 36.1 40.3 173.9 180.9 156.9 261.5 180.9 210.1 170.8 180.3 191.2 166.9 183.6 179.1 102.5 125.0 160.1 39.8 75.8 363.5 572.5 292.0 75.1 46.9 198.6 103.6 130.1 123.0 242.0 110.3 10.4 443.3 106.2 103.2 246.5 269.1 46.9 231.7 235.5 146.6 178.6 68.5 109.6 129.9 1214.1 266.0 90.7 187.2 155.8 153.5 118.5 196.8 163.6 58.9 104.4 202.0 219.7 61.7 254.9 34.2 330.9 90.8 188.5 32.8 68.7 117.0 40.2 59.3 78.2 176.8 118.9 574.8 120.9 332.7 105.1 282.9 429.7 38.8 144.7 164.9 287.9 37.2 48.0 112.7 317.8 583.5 118.2 171.5 134.4 396.8 MSH2 "COCA1, HNPCC, HNPCC1" ENSG00000095002 "MutS homolog 2" P43246 2 47403067-47663146 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "testis cancer: 46.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009572, HPA066845, CAB070867" Approved Supported Nucleoplasm,Vesicles NA Yes 28000 "Cluster 48: NK-cells - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Vesicles "CAB009572: AB_2144828, CAB070867: , HPA066845: AB_2732752" "unprognostic (2.35e-1)" "unprognostic (1.54e-2)" "unprognostic (2.89e-3)" "prognostic unfavorable (4.44e-4)" "unprognostic (2.23e-1)" "unprognostic (6.31e-3)" "prognostic unfavorable (1.72e-9)" "unprognostic (1.77e-1)" "unprognostic (7.09e-3)" "unprognostic (8.57e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (5.38e-2)" "unprognostic (3.29e-3)" "unprognostic (1.20e-3)" "unprognostic (5.74e-1)" "unprognostic (8.46e-2)" "unprognostic (1.48e-1)" 8.1 7.5 8.3 12.8 10.5 15.7 15.7 14.6 10.6 9.7 12.2 11.9 7.8 11.7 14.0 9.5 12.4 5.8 10.1 9.6 9.0 8.2 6.7 8.1 23.7 8.6 8.0 8.7 6.5 14.8 6.2 11.6 9.5 8.6 15.0 34.9 8.5 7.7 7.1 11.1 9.3 8.8 8.5 10.8 8.1 16.2 7.9 32.6 15.8 7.2 25.0 7.9 6.4 8.9 114.3 35.3 103.3 57.9 7.3 21.2 64.3 62.9 33.3 80.9 76.9 72.3 50.1 141.2 84.6 23.8 56.6 49.8 78.6 37.4 122.3 68.1 55.8 99.3 42.3 65.6 7.7 97.7 34.9 12.3 11.2 68.1 19.0 19.1 45.2 3.9 165.1 34.0 63.1 44.2 119.6 75.4 195.7 69.3 45.1 151.1 182.2 84.4 35.8 57.3 85.9 91.6 58.4 49.2 48.0 83.6 46.9 38.8 18.7 55.5 70.9 57.1 74.6 20.8 63.4 180.1 33.1 72.5 35.4 3.0 1.3 4.9 8.0 4.4 9.3 6.7 7.7 10.3 2.5 7.9 12.6 13.1 1.0 14.2 3.9 3.4 11.8 6.5 8.3 10.5 14.6 10.6 9.6 9.0 8.6 8.0 9.5 8.5 7.9 8.9 14.7 9.6 11.5 18.6 13.0 8.3 7.9 14.4 8.6 17.4 7.5 7.1 15.6 5.7 12.6 9.2 45.9 19.9 14.2 6.6 3.9 11.5 17.8 21.0 11.3 13.4 3.5 54.1 59.9 8.4 20.7 12.2 7.1 18.8 12.0 28.2 5.0 1.6 11.4 11.8 58.0 12.1 14.2 4.1 4.6 22.8 5.3 5.1 8.8 16.9 5.5 22.6 17.5 35.7 54.7 7.3 5.0 6.4 12.4 2.8 5.4 4.5 23.3 41.1 0.0 9.8 9.0 56.5 50.8 9.3 6.5 5.1 12.8 24.3 13.5 3.8 MSH6 GTBP ENSG00000116062 "MutS homolog 6" P52701 2 47695530-47810063 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" DNA-binding "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 119.6;Theca cells: 114.9" "Cancer enhanced" "Detected in all" "testis cancer: 31.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009091, HPA028376, HPA028446, CAB070870" Enhanced Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA Yes 15000 "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Golgi apparatus, Vesicles" "CAB009091: AB_670083, CAB070870: AB_2144959, HPA028376: AB_10598909, HPA028446: AB_10602182" "unprognostic (5.10e-2)" "unprognostic (5.87e-3)" "unprognostic (3.29e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (1.98e-1)" "unprognostic (3.09e-2)" "prognostic unfavorable (7.86e-4)" "unprognostic (1.79e-1)" "unprognostic (2.35e-3)" "unprognostic (1.01e-1)" "unprognostic (1.74e-3)" "unprognostic (8.99e-2)" "prognostic unfavorable (1.06e-7)" "unprognostic (1.22e-1)" "unprognostic (2.31e-1)" "unprognostic (9.68e-2)" "unprognostic (3.48e-2)" 11.7 22.7 9.3 17.7 13.7 24.0 16.2 15.0 12.7 15.5 12.7 13.0 9.0 27.7 10.2 11.7 17.8 10.9 9.3 8.9 11.5 12.1 19.8 11.6 28.4 12.7 11.7 53.0 31.3 17.0 9.8 20.3 13.0 15.0 12.4 21.6 10.8 15.6 10.5 13.1 9.8 27.2 10.7 12.7 10.9 35.3 11.3 36.3 17.2 11.2 31.0 12.8 12.2 19.9 116.5 77.6 128.4 37.5 42.3 46.3 67.9 63.6 51.1 60.2 59.8 67.2 41.4 158.1 84.5 59.5 82.0 46.0 130.3 74.3 82.1 80.7 69.0 117.0 60.8 71.1 28.8 131.5 37.8 38.6 28.3 60.7 41.6 53.8 40.8 5.3 115.9 69.8 61.8 85.5 144.2 80.1 130.7 81.3 37.7 219.6 204.3 84.7 44.5 76.2 92.8 100.3 79.1 40.4 42.7 124.3 54.6 42.6 33.4 72.2 92.3 54.6 80.6 63.8 79.3 276.2 61.9 77.9 42.4 7.7 3.7 3.8 4.8 6.2 5.5 4.3 5.5 5.0 5.5 4.2 8.4 4.5 2.5 5.9 6.4 2.7 5.3 3.6 9.3 13.7 15.0 12.7 8.9 11.5 12.7 11.7 13.0 10.7 11.3 19.9 19.8 28.9 21.4 5.9 19.2 25.2 22.0 12.3 31.9 25.4 14.4 15.1 8.6 2.8 21.8 7.3 35.5 35.6 20.7 7.4 3.9 15.7 46.4 27.1 31.1 18.4 4.8 47.1 8.5 9.6 21.8 24.0 8.6 31.7 17.7 119.6 13.6 10.2 13.0 15.2 12.1 9.7 20.3 5.6 13.2 17.5 25.4 16.8 3.6 7.5 10.0 22.7 8.2 9.5 27.4 9.1 3.7 22.6 31.1 16.1 2.6 6.7 22.1 31.4 6.6 27.4 33.0 54.3 48.8 22.0 17.5 9.6 19.8 114.9 12.1 11.7 MTHFD1 "MTHFC, MTHFD" ENSG00000100714 "Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1" 14 64388031-64463457 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 356.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 142.9;Proximal tubular cells: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000704, HPA001290, HPA015006, HPA050052" Approved Enhanced Cytosol NA Yes "Cluster 43: B-cells - Humoral immune response" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA000704: AB_1079424, HPA001290: AB_1854177, HPA015006: AB_1854178, HPA050052: AB_2680998" "unprognostic (3.58e-2)" "unprognostic (5.50e-3)" "unprognostic (1.24e-1)" "unprognostic (2.46e-2)" "unprognostic (1.37e-1)" "unprognostic (7.01e-2)" "unprognostic (8.85e-3)" "unprognostic (7.62e-3)" "unprognostic (1.28e-1)" "unprognostic (2.29e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (1.84e-1)" "prognostic favorable (5.93e-5)" "unprognostic (2.45e-2)" "unprognostic (1.75e-1)" "unprognostic (7.30e-2)" "unprognostic (2.29e-2)" 56.4 18.0 8.6 20.0 17.4 27.0 29.8 8.3 12.3 16.9 15.0 23.3 19.7 16.1 9.9 25.1 16.0 13.1 28.1 12.9 8.1 55.3 356.9 15.4 23.6 7.5 7.8 24.9 23.8 27.5 9.2 13.3 7.0 12.9 27.5 3.6 15.6 13.8 64.1 17.1 18.9 20.0 7.2 14.5 17.9 4.7 8.9 30.2 20.5 61.9 27.7 18.6 16.6 8.3 294.1 164.9 58.5 143.6 70.5 53.4 95.7 106.4 83.3 148.1 147.4 161.2 144.2 103.3 49.6 67.1 68.3 146.0 177.6 111.2 160.4 107.3 117.9 122.2 143.5 131.8 50.6 104.5 81.2 43.0 37.3 124.3 66.4 57.5 93.1 98.1 108.5 98.7 114.7 270.1 179.9 62.3 118.0 186.5 160.4 138.3 201.2 114.4 110.5 160.9 128.7 49.0 183.7 111.4 58.3 54.0 164.4 58.6 51.5 115.1 184.1 102.2 134.2 58.8 65.6 177.9 107.4 125.2 134.8 0.4 11.7 0.1 9.7 19.5 13.0 27.0 10.1 12.3 17.7 15.3 7.8 10.7 0.9 17.8 16.7 4.0 19.5 12.2 8.6 17.4 8.3 12.3 12.9 8.1 7.5 7.8 7.0 7.2 8.9 8.3 8.1 19.2 23.5 15.0 16.2 13.8 14.2 14.7 13.6 0.0 9.8 8.1 43.9 15.7 19.5 16.5 0.0 30.6 10.8 7.9 41.1 16.9 1.4 6.8 11.7 12.3 3.0 42.3 19.5 10.3 30.9 14.9 15.3 8.7 50.7 27.2 12.8 142.9 25.3 0.0 15.6 14.3 2.0 13.0 11.0 1.5 13.1 12.3 14.2 8.4 13.3 0.0 8.2 14.1 10.9 11.7 6.3 13.2 24.1 10.2 8.2 75.3 11.5 0.0 19.7 13.1 19.3 0.9 8.9 19.5 10.7 9.9 16.6 21.4 24.6 12.7 MYO19 "FLJ22865, MYOHD1" ENSG00000278259 "Myosin XIX" Q96H55 17 36495636-36543435 "Predicted intracellular proteins" "Actin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 81.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021415, HPA059715" Approved Enhanced Mitochondria,Cytosol NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Mitochondria Cytosol "HPA021415: AB_2266815, HPA059715: AB_2684111" "unprognostic (3.12e-1)" "unprognostic (2.38e-1)" "unprognostic (8.44e-3)" "unprognostic (1.46e-1)" "unprognostic (2.02e-1)" "unprognostic (4.89e-3)" "prognostic unfavorable (8.33e-6)" "unprognostic (1.07e-3)" "unprognostic (1.39e-2)" "unprognostic (2.41e-1)" "unprognostic (1.67e-1)" "unprognostic (3.70e-3)" "unprognostic (1.47e-2)" "unprognostic (1.50e-2)" "unprognostic (1.57e-1)" "unprognostic (1.89e-1)" "unprognostic (4.17e-2)" 7.8 5.5 2.3 7.1 2.6 13.1 8.0 2.3 3.0 11.3 3.5 11.7 13.0 7.3 5.2 22.1 7.5 4.9 5.6 2.3 2.4 13.5 11.1 7.8 5.7 3.0 2.4 6.8 13.2 17.0 9.5 6.4 3.2 7.9 14.6 2.1 15.4 3.9 8.5 24.2 13.0 7.2 2.2 8.4 14.4 9.6 2.9 6.4 9.4 4.5 10.0 7.3 14.5 3.1 41.6 47.3 21.7 25.1 10.1 12.5 32.5 34.0 27.0 53.2 57.9 42.6 46.4 21.9 15.6 23.3 20.0 66.5 48.0 38.3 36.8 18.9 24.0 30.6 58.8 29.4 8.4 36.5 40.0 6.9 20.2 41.6 40.8 13.5 22.2 29.7 46.5 24.2 28.2 28.9 25.3 29.4 23.9 44.1 20.4 32.8 30.7 28.4 27.7 32.3 37.9 18.5 44.9 31.7 15.4 30.3 55.2 17.6 15.9 32.8 41.1 47.5 65.3 19.8 41.4 21.3 22.8 24.7 44.5 0.5 0.6 0.4 1.1 0.4 0.9 0.6 0.7 1.1 1.2 0.5 0.6 1.2 0.0 1.4 0.2 0.6 0.6 0.4 2.3 2.6 2.3 3.0 2.3 2.4 3.0 2.4 3.2 2.2 2.9 3.1 13.1 9.6 12.0 23.8 12.3 29.6 12.3 14.4 23.9 18.4 11.0 12.3 4.4 17.2 8.6 5.5 35.5 12.0 9.6 24.4 1.9 10.7 81.4 10.6 12.7 10.6 10.8 24.6 25.8 13.3 21.6 9.6 23.9 16.7 2.5 20.4 6.8 9.5 10.9 3.3 36.4 23.5 14.2 7.9 10.1 20.8 12.5 7.8 3.6 10.3 11.0 3.9 15.5 22.6 24.4 16.4 13.9 9.8 19.4 26.4 23.0 4.4 6.4 24.8 0.0 13.3 9.0 19.7 19.4 29.1 23.4 7.3 13.0 9.9 32.5 16.3 MZT1 "C13orf37, FLJ21869, LOC440145, MGC150539, MOZART1, RP11-11C5.2" ENSG00000204899 "Mitotic spindle organizing protein 1" Q08AG7 13 72708367-72727629 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 122.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063299, HPA066715" Approved NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 32: U-937 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" "HPA063299: AB_2684980, HPA066715: AB_2685709" "unprognostic (1.52e-1)" "unprognostic (3.38e-2)" "unprognostic (1.48e-1)" "unprognostic (4.89e-1)" "unprognostic (2.46e-1)" "unprognostic (2.38e-3)" "prognostic unfavorable (3.22e-5)" "unprognostic (2.65e-2)" "unprognostic (6.88e-2)" "unprognostic (5.28e-2)" "unprognostic (7.09e-2)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.01e-5)" "unprognostic (9.01e-3)" "unprognostic (5.23e-1)" "unprognostic (1.60e-1)" "unprognostic (1.26e-1)" 9.0 15.1 11.8 11.6 15.5 26.3 11.6 12.6 18.4 8.6 10.2 8.8 8.3 8.3 9.1 9.8 6.1 6.1 12.0 12.3 12.7 11.1 5.5 8.1 17.2 10.4 11.3 7.3 5.8 8.2 6.7 10.6 10.1 10.3 10.0 9.9 9.5 6.3 19.2 9.6 7.4 7.2 11.3 9.8 9.2 6.4 13.1 17.5 12.1 15.0 13.1 9.3 6.1 10.8 97.5 15.4 53.1 39.4 10.8 18.0 43.5 77.1 31.9 47.7 54.8 28.9 62.3 66.9 57.5 30.9 30.1 30.8 53.6 28.7 86.1 80.6 54.5 86.9 30.0 44.0 15.0 147.1 68.1 9.8 28.8 28.9 59.4 28.8 49.1 76.7 48.7 51.1 95.1 17.5 75.2 81.9 40.5 58.7 28.7 52.6 60.7 33.2 42.9 23.8 62.3 56.9 32.7 47.8 48.4 29.0 36.1 72.1 33.5 41.9 47.7 59.5 94.8 46.5 77.0 53.1 98.2 88.8 87.6 16.2 3.8 8.5 4.8 6.9 6.0 7.7 6.5 6.0 4.8 7.3 8.3 6.7 2.0 7.2 7.6 6.3 9.9 3.8 11.8 15.5 12.6 18.4 12.3 12.7 10.4 11.3 10.1 11.3 13.1 10.8 29.3 0.0 15.2 5.5 49.9 55.1 27.6 32.2 30.7 29.3 32.8 24.5 17.8 12.8 18.7 31.3 14.6 57.3 38.3 10.3 58.7 25.9 4.5 20.5 18.0 26.5 21.7 122.3 15.2 24.4 98.8 23.1 18.3 18.8 18.4 27.0 20.7 8.8 41.3 63.9 17.1 17.6 38.7 32.3 46.4 4.2 19.9 33.1 60.5 3.7 36.0 31.1 23.7 6.0 10.0 25.1 15.2 16.6 47.9 33.7 8.1 46.5 12.9 27.7 32.9 21.4 26.8 52.0 38.2 51.9 57.4 30.2 43.8 17.6 24.2 32.3 NACA NACA1 ENSG00000196531 "Nascent polypeptide associated complex subunit alpha" "E9PAV3, Q13765" 12 56712305-56731628 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport" "Activator, Chaperone, DNA-binding" Allergen "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA073152, HPA073648" Approved Cytosol NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Cytosol "HPA073152: AB_2686575, HPA073648: AB_2686621" "unprognostic (3.35e-2)" "unprognostic (9.98e-3)" "unprognostic (1.56e-1)" "unprognostic (2.30e-3)" "unprognostic (4.03e-2)" "unprognostic (2.81e-1)" "unprognostic (1.24e-3)" "unprognostic (1.55e-1)" "unprognostic (3.92e-2)" "unprognostic (2.95e-2)" "unprognostic (5.64e-2)" "unprognostic (8.45e-2)" "prognostic unfavorable (4.58e-11)" "unprognostic (9.47e-2)" "unprognostic (6.28e-2)" "unprognostic (7.00e-2)" "unprognostic (9.79e-2)" 1348.3 1065.0 446.1 607.2 455.9 1524.0 1460.8 456.4 614.8 1642.2 421.9 1252.3 618.6 1067.1 1084.0 1511.9 1216.9 545.1 946.9 431.4 473.1 1038.4 893.7 839.1 1026.5 465.7 442.5 2391.0 1384.8 764.5 811.6 607.7 469.4 1139.7 845.2 453.0 1016.0 699.0 1192.4 1706.1 890.4 689.9 492.3 901.9 1035.1 364.0 450.6 1043.6 918.0 376.8 1432.0 1183.1 1447.1 485.1 1128.5 1333.7 1555.7 1198.7 1795.5 3053.1 1489.5 1117.9 1619.4 1509.9 1051.6 1602.0 1220.7 2014.8 1191.0 1019.4 599.8 963.6 1324.0 1814.9 1600.2 1002.6 2111.7 1463.4 890.3 1640.8 1607.2 2139.1 899.1 2430.3 2204.4 1226.9 2477.6 2669.6 1628.2 1184.8 1896.0 2594.7 1445.5 1118.9 1341.7 2670.1 1528.3 1072.6 1440.8 1543.1 1268.7 2180.1 2124.9 1157.6 1130.2 1197.4 835.8 1977.1 1774.5 1027.8 2109.8 2398.2 1085.4 770.4 933.2 834.0 1127.0 1217.9 1475.1 1768.0 1134.0 1422.3 997.9 462.6 987.0 503.8 581.4 1371.7 851.7 969.7 823.0 726.5 1006.8 812.1 941.6 834.7 350.2 748.7 1842.6 1082.7 944.3 1951.8 446.1 455.9 456.4 614.8 431.4 473.1 465.7 442.5 469.4 492.3 450.6 485.1 1444.2 445.5 645.8 38.8 1822.8 2027.4 2219.5 2022.2 2405.1 325.2 2494.6 5365.8 722.7 1159.6 1095.8 395.4 66.7 1867.2 2037.7 656.8 1778.5 1368.9 701.0 899.4 1625.1 1206.0 647.6 1213.0 31.4 2023.3 2894.2 1085.3 649.4 1079.9 735.9 1600.7 993.4 881.6 1594.4 183.4 35.5 1461.3 801.5 1436.7 1664.7 589.5 2409.8 1430.9 1239.8 40.3 2261.1 1195.0 1528.3 26.7 35.1 1574.8 1306.2 1431.2 1160.8 2248.0 1444.7 2734.4 523.2 455.2 802.0 1977.5 1718.3 542.4 479.1 2363.5 2231.6 2323.4 1549.8 2175.1 1762.0 2618.2 NASP "DKFZp547F162, FLB7527, FLJ31599, FLJ35510, MGC19722, MGC20372, MGC2297, PRO1999" ENSG00000132780 "Nuclear autoantigenic sperm protein" P49321 1 45583846-45618904 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 476.2;Spermatogonia: 514.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028136, HPA030518, HPA030520" Enhanced Enhanced Nucleoplasm NA Yes 170000 "Cluster 24: B-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 5: NTERA-2 - Transcription" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA028136: AB_2672497, HPA030518: AB_2673509, HPA030520: AB_2673510" "unprognostic (5.59e-2)" "unprognostic (1.34e-3)" "unprognostic (5.02e-1)" "unprognostic (2.24e-1)" "unprognostic (1.23e-1)" "unprognostic (5.36e-3)" "prognostic unfavorable (4.96e-6)" "unprognostic (2.59e-1)" "prognostic unfavorable (3.67e-4)" "unprognostic (1.56e-2)" "unprognostic (1.15e-1)" "unprognostic (1.78e-2)" "prognostic unfavorable (1.91e-8)" "unprognostic (1.62e-2)" "unprognostic (4.83e-2)" "unprognostic (7.73e-2)" "unprognostic (5.32e-2)" 66.2 39.6 57.4 55.9 62.6 165.0 58.8 60.6 95.7 67.4 57.1 52.7 34.6 54.6 29.9 55.2 65.6 26.7 51.0 57.2 68.0 48.6 52.0 50.4 91.5 65.0 61.6 72.4 34.9 41.1 40.9 61.9 63.0 54.1 51.5 38.2 43.5 43.4 41.7 46.7 58.3 45.1 56.0 83.3 47.3 108.9 62.4 100.7 48.1 22.2 97.7 51.1 56.0 65.3 191.3 110.8 520.2 184.6 85.8 44.9 243.8 150.9 112.4 230.5 286.5 205.7 134.4 357.9 103.5 65.8 251.9 180.2 351.9 161.0 291.5 164.0 222.9 462.7 201.6 326.9 30.2 489.3 186.4 52.5 38.3 254.0 87.6 60.1 159.5 294.8 396.3 204.1 157.6 131.4 559.6 445.0 755.5 189.5 93.1 697.4 454.0 343.8 115.3 189.4 198.3 239.8 248.7 140.4 159.7 389.2 100.8 377.0 86.7 105.5 322.8 204.4 250.0 124.5 251.2 616.2 107.6 306.7 107.3 6.4 9.4 10.9 14.1 12.1 16.4 16.1 16.1 16.3 14.3 22.3 13.9 13.7 4.0 9.7 7.3 14.7 22.0 9.1 57.4 62.6 60.6 95.7 57.2 68.0 65.0 61.6 63.0 56.0 62.4 65.3 196.5 57.7 106.7 70.8 136.1 78.1 135.2 72.4 133.7 45.3 77.4 87.4 58.4 37.1 99.1 36.8 37.5 319.3 150.8 64.8 31.3 55.0 16.6 119.6 138.1 138.4 51.3 142.8 32.7 37.4 223.2 100.6 81.1 137.9 115.2 134.2 90.3 38.6 108.1 43.7 34.8 68.1 44.7 43.7 62.6 26.6 94.8 82.7 40.9 31.9 52.3 60.9 62.8 63.8 160.3 29.8 44.9 78.2 107.4 88.6 28.9 36.6 109.1 77.3 85.5 148.1 106.6 476.2 514.5 92.1 57.0 268.2 142.2 90.7 101.7 85.3 NDE1 "FLJ20101, NDE, nudE" ENSG00000072864 "NudE neurodevelopment protein 1" Q9NXR1 16 15643267-15734691 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis" "Developmental protein" Lissencephaly "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 105.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "granulocytes: 21.8;monocytes: 11.7;NK-cells: 8.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024075 Approved NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" "HPA024075: AB_1854336" "unprognostic (1.09e-1)" "unprognostic (1.66e-1)" "unprognostic (3.26e-1)" "unprognostic (1.47e-1)" "unprognostic (3.84e-1)" "unprognostic (4.11e-2)" "prognostic unfavorable (9.92e-4)" "unprognostic (1.43e-2)" "unprognostic (1.59e-1)" "unprognostic (4.55e-2)" "unprognostic (3.70e-3)" "unprognostic (1.16e-1)" "prognostic unfavorable (8.19e-4)" "unprognostic (1.29e-1)" "unprognostic (3.28e-2)" "unprognostic (2.22e-1)" "unprognostic (2.93e-2)" 9.2 5.8 12.1 13.0 23.6 25.6 9.4 22.5 15.6 14.6 6.9 25.0 7.5 11.6 2.6 17.7 11.1 9.8 10.6 11.2 16.1 6.3 4.2 11.1 20.4 30.0 24.5 7.5 4.0 4.0 3.1 10.0 26.5 14.2 7.3 2.0 12.2 5.1 7.3 27.6 12.9 10.7 17.0 12.5 10.1 11.1 21.3 23.4 6.3 7.9 20.9 15.3 19.8 43.2 37.0 33.0 34.2 39.9 11.4 18.6 10.4 15.4 21.0 30.4 34.5 18.3 58.3 21.9 24.0 23.2 16.7 34.5 25.3 47.3 20.8 33.7 16.0 24.6 35.3 51.7 16.3 33.3 37.2 6.6 28.9 28.8 52.0 16.9 40.6 27.9 20.5 80.5 26.6 43.9 43.0 30.5 30.5 26.5 14.3 64.8 32.3 34.8 11.6 24.1 17.0 21.0 27.5 40.7 27.6 25.9 42.8 34.3 12.5 26.9 17.6 43.2 36.1 17.4 13.1 38.1 27.5 43.0 55.0 5.1 4.7 15.0 3.0 3.8 1.7 3.3 3.0 1.3 3.4 1.9 1.8 2.0 21.8 8.5 11.7 3.1 3.3 3.9 12.1 23.6 22.5 15.6 11.2 16.1 30.0 24.5 26.5 17.0 21.3 43.2 11.7 3.2 4.4 11.1 36.1 26.0 32.7 19.0 24.5 7.0 9.5 10.4 2.0 4.3 8.9 5.5 6.2 3.9 25.0 9.6 0.0 4.5 46.9 17.1 23.1 11.6 4.2 49.0 2.1 5.3 5.3 11.8 19.4 15.0 10.8 15.5 8.6 1.7 10.1 3.3 2.4 7.4 2.0 15.8 11.0 58.5 15.8 19.3 12.4 22.5 53.0 7.4 50.4 9.5 105.5 7.1 4.2 6.0 16.6 26.3 4.6 1.9 13.3 6.5 6.6 6.9 9.5 13.8 10.0 18.8 30.7 2.5 28.3 9.8 10.2 21.6 NDUFAF4 "bA22L21.1, C6orf66, HRPAP20, HSPC125, My013" ENSG00000123545 "NADH:ubiquinone oxidoreductase complex assembly factor 4" Q9P032 6 96889315-96897891 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction" Calmodulin-binding "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 168.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046560 Uncertain Supported Mitochondria NA Yes "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA046560: AB_10966700" "prognostic unfavorable (1.31e-4)" "unprognostic (1.32e-1)" "unprognostic (1.09e-2)" "unprognostic (1.14e-3)" "unprognostic (2.89e-1)" "unprognostic (7.53e-3)" "unprognostic (6.89e-2)" "unprognostic (1.27e-1)" "unprognostic (5.57e-2)" "unprognostic (2.78e-2)" "unprognostic (2.03e-2)" "unprognostic (1.13e-1)" "unprognostic (4.20e-3)" "unprognostic (6.32e-2)" "unprognostic (1.11e-1)" "unprognostic (4.87e-2)" "unprognostic (1.31e-1)" 5.7 7.9 13.3 3.4 14.7 2.2 7.0 16.8 21.4 6.4 10.4 7.4 4.9 5.5 4.7 5.4 4.4 4.5 25.6 14.7 15.6 12.6 9.3 3.2 4.7 14.9 14.5 7.8 5.5 10.1 2.5 4.8 15.6 7.2 7.5 9.8 6.2 9.6 23.2 4.8 4.4 5.6 12.3 4.9 4.7 4.6 16.6 5.3 7.4 31.1 4.7 7.8 3.7 13.7 2.2 6.1 10.5 14.3 10.3 5.9 5.6 6.0 5.6 8.8 6.6 8.4 3.7 20.6 10.7 5.6 8.4 4.4 24.7 9.3 8.5 14.5 19.5 23.0 3.2 7.4 11.2 24.4 9.2 5.7 14.2 7.6 7.7 4.4 6.9 14.3 21.0 13.6 13.9 7.0 15.7 13.1 20.1 11.3 10.0 7.4 5.9 10.7 14.6 6.0 17.9 8.4 3.1 10.7 17.5 10.2 3.3 16.1 5.8 4.6 3.5 16.2 9.9 3.1 5.4 20.0 6.2 18.1 6.9 0.2 1.8 0.5 4.0 3.6 5.3 5.1 5.2 5.4 3.3 5.4 7.6 6.9 0.3 3.0 2.3 3.8 5.9 3.2 13.3 14.7 16.8 21.4 14.7 15.6 14.9 14.5 15.6 12.3 16.6 13.7 31.9 9.6 19.8 9.8 43.2 108.8 74.4 82.6 60.9 15.1 28.5 48.1 126.9 25.8 37.3 23.9 0.0 49.6 27.9 23.5 168.3 37.7 3.3 19.2 18.3 30.7 39.3 23.3 18.5 27.6 47.6 34.4 33.6 15.9 20.3 42.5 26.0 51.8 53.9 26.9 17.8 44.3 67.1 18.3 33.7 6.2 26.1 20.2 55.2 11.2 19.7 20.7 24.7 8.0 13.1 21.4 19.7 24.8 40.6 63.7 24.2 118.0 16.6 16.6 26.3 57.8 49.1 42.3 63.7 63.1 96.7 32.8 34.3 43.4 58.1 46.4 NECTIN2 "CD112, HVEB, PRR2, PVRL2, PVRR2" ENSG00000130202 "Nectin cell adhesion molecule 2" Q92692 19 44846175-44889223 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 136.6;Ductal cells: 215.6;Exocrine glandular cells: 154.2;Glandular and luminal cells: 126.1;Pancreatic endocrine cells: 241.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 10.4" "Lineage enhanced" "Detected in many" "granulocytes: 10.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012759, CAB026138, HPA073459" Enhanced Approved "Nucleoli fibrillar center,Cell Junctions" NA Yes 5900000 "Cluster 52: Eosinophils - Transcription" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 39: CACO-2 - Unknown function" "Cluster 7: Non-specific - Mitochondria" "Nucleoli fibrillar center, Cell Junctions" "CAB026138: , HPA012759: AB_1846227, HPA073459: " "unprognostic (3.30e-2)" "unprognostic (2.84e-1)" "unprognostic (1.07e-1)" "unprognostic (5.61e-3)" "unprognostic (7.45e-2)" "unprognostic (2.21e-1)" "unprognostic (1.66e-2)" "unprognostic (6.63e-2)" "unprognostic (2.85e-1)" "unprognostic (2.97e-1)" "unprognostic (6.93e-2)" "unprognostic (3.19e-1)" "unprognostic (1.60e-1)" "unprognostic (2.15e-1)" "unprognostic (1.61e-1)" "unprognostic (8.19e-2)" "unprognostic (2.05e-1)" 71.4 79.1 30.8 32.1 28.4 15.8 66.0 29.8 34.3 41.7 44.3 42.3 55.3 45.0 58.2 76.3 43.9 52.5 71.3 29.2 33.1 79.6 118.5 72.9 15.8 35.8 33.0 41.7 55.0 61.5 39.1 77.2 32.9 69.2 32.8 16.7 62.6 30.4 20.1 52.5 47.5 31.3 31.8 58.1 75.4 65.8 34.7 6.9 57.4 17.7 25.3 55.8 49.3 28.9 73.8 89.3 118.3 140.6 59.3 35.8 123.7 62.6 83.9 120.4 136.6 194.8 171.0 0.6 79.2 79.0 61.1 98.5 106.6 55.6 91.7 3.2 53.2 43.0 30.8 128.6 145.0 0.7 117.9 64.9 22.5 56.2 44.8 123.2 149.3 3.0 71.1 0.7 59.2 146.4 0.6 5.6 92.8 249.8 27.7 4.3 37.7 3.2 139.5 100.1 5.4 15.2 74.9 127.0 28.7 210.4 97.2 47.1 140.1 31.3 105.5 23.7 48.6 9.0 25.8 0.6 57.3 10.0 83.0 1.8 2.0 10.4 0.0 0.7 0.2 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.8 0.0 0.4 0.3 0.0 0.7 30.8 28.4 29.8 34.3 29.2 33.1 35.8 33.0 32.9 31.8 34.7 28.9 136.6 35.3 31.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 108.4 54.9 0.0 0.0 6.8 58.8 0.0 109.3 2.6 0.0 3.9 215.6 0.0 73.8 66.3 58.8 0.0 0.0 0.0 154.2 97.8 30.4 0.0 126.1 3.8 75.0 0.0 0.0 54.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.2 0.0 0.0 80.1 0.0 0.0 0.0 0.0 241.8 0.0 0.0 0.1 0.0 0.0 27.1 3.6 0.0 0.0 0.0 42.9 0.0 0.0 0.0 0.0 101.8 2.2 58.3 0.0 0.0 NEK2 "NEK2A, NLK1, PPP1R111, RP67" ENSG00000117650 "NIMA related kinase 2" P51955 1 211658657-211675630 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 17.9;lymphoid tissue: 19.2;testis: 67.1" "Group enriched" "Detected in many" 4 "Early spermatids: 76.1;Spermatocytes: 244.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 5.7" "Low region specificity" "Detected in all" "CAB017530, HPA064967" Enhanced Supported Nucleoplasm,Centrosome NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Centrosome" "CAB017530: AB_1126558, HPA064967: AB_2685393" "unprognostic (1.28e-1)" "unprognostic (2.33e-1)" "unprognostic (1.02e-1)" "unprognostic (8.51e-2)" "unprognostic (1.83e-1)" "unprognostic (1.35e-2)" "prognostic unfavorable (9.47e-6)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.95e-2)" "unprognostic (2.00e-2)" "unprognostic (1.09e-3)" "unprognostic (8.49e-2)" "unprognostic (0.00e+0)" "unprognostic (8.21e-2)" "unprognostic (4.11e-2)" "unprognostic (1.25e-2)" "unprognostic (2.71e-1)" 0.7 0.4 0.5 5.3 0.4 17.9 1.5 0.9 0.6 1.1 0.6 5.9 7.4 1.3 0.5 4.4 2.2 0.8 0.4 0.5 0.3 0.3 0.7 0.7 9.0 0.4 0.2 0.4 0.1 0.1 0.0 3.2 0.3 2.5 7.6 1.5 0.8 0.2 0.4 4.3 6.9 2.0 0.2 1.7 2.7 67.1 0.6 19.2 0.4 0.2 10.6 1.3 1.6 0.9 86.0 60.5 45.3 32.6 2.6 4.5 49.7 32.4 30.1 55.4 47.5 32.3 81.7 45.1 15.2 25.2 35.1 44.5 39.9 24.2 69.6 69.5 33.2 21.6 51.4 44.2 0.4 43.2 28.3 1.4 2.9 42.9 45.9 13.4 36.3 45.2 59.9 76.9 56.0 23.6 47.3 28.8 43.0 55.0 30.5 46.2 69.2 68.7 19.7 24.2 41.0 45.0 46.6 51.5 39.3 38.4 79.4 25.1 19.0 27.6 54.1 54.8 88.3 31.6 62.6 59.6 24.1 32.6 46.8 1.2 0.1 0.1 0.1 0.1 0.0 0.5 0.1 0.1 0.0 0.4 0.3 0.2 0.7 1.5 0.1 0.2 1.6 0.3 0.5 0.4 0.9 0.6 0.5 0.3 0.4 0.2 0.3 0.2 0.6 0.9 0.1 0.0 0.5 0.3 1.7 2.9 0.7 3.8 0.6 11.3 1.9 2.2 0.5 0.0 2.9 0.0 0.0 9.4 0.8 1.9 0.0 0.2 76.1 15.2 0.7 0.8 0.0 39.6 0.8 0.2 14.1 1.4 5.6 1.5 0.0 3.6 3.6 0.7 5.8 3.3 0.0 3.2 10.2 2.5 1.1 39.0 2.5 2.1 0.0 0.0 0.0 1.6 2.1 0.0 0.1 0.0 2.5 0.7 5.4 0.7 2.1 0.1 5.2 1.8 6.6 0.0 1.5 244.2 26.1 8.6 1.7 1.4 2.0 0.9 9.5 1.4 NOL4L "C20orf112, C20orf113, dJ1184F4.2, dJ1184F4.4, DKFZP566G1424" ENSG00000197183 "Nucleolar protein 4 like" Q96MY1 20 32443059-32585074 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 49.3;testis: 50.0" "Cell type enhanced" "Detected in many" "Early spermatids: 107.4;Late spermatids: 171.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CACO-2: 73.4;HEL: 58.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041768, HPA043600" Enhanced Enhanced Nucleoplasm NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 77: Retina - Visual perception" "Cluster 39: CACO-2 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA041768: AB_10964172, HPA043600: AB_10961001" "unprognostic (4.33e-2)" "unprognostic (1.71e-1)" "unprognostic (4.03e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (3.10e-1)" "unprognostic (7.88e-2)" "unprognostic (2.75e-3)" "unprognostic (1.65e-2)" "unprognostic (1.83e-1)" "unprognostic (1.41e-1)" "unprognostic (1.84e-1)" "unprognostic (1.72e-1)" "unprognostic (3.88e-2)" "unprognostic (9.32e-2)" "unprognostic (3.42e-1)" "unprognostic (6.08e-3)" "prognostic favorable (2.63e-4)" 10.4 9.1 12.8 8.7 17.5 20.8 10.2 20.8 19.9 8.7 3.1 17.2 18.7 6.6 12.0 2.5 8.6 8.6 5.6 13.2 14.7 14.5 7.0 13.4 8.0 14.5 13.5 4.0 11.1 4.3 22.3 11.1 14.8 8.7 13.6 49.3 9.7 8.2 1.6 3.5 19.8 6.5 10.3 12.9 13.2 50.0 13.1 15.1 9.7 1.7 5.8 9.7 5.2 19.5 9.1 27.4 16.9 11.6 3.6 5.4 2.3 5.7 4.6 7.1 4.9 73.4 20.8 0.6 16.6 7.5 11.0 2.5 5.4 15.9 3.2 2.1 4.3 58.2 14.5 53.2 9.3 0.9 3.3 13.6 2.2 5.2 3.4 16.1 43.1 12.5 17.7 7.6 3.4 5.1 19.3 17.8 9.9 27.7 25.3 8.2 2.1 3.0 12.0 1.6 22.3 18.1 17.9 0.4 9.8 17.4 3.7 17.8 45.5 6.6 22.6 6.1 5.9 5.6 2.1 4.0 7.2 31.4 20.3 2.9 2.0 1.2 5.8 4.5 5.1 1.6 3.8 3.4 2.1 1.1 7.6 6.4 6.5 8.3 12.1 0.2 6.9 4.9 12.8 17.5 20.8 19.9 13.2 14.7 14.5 13.5 14.8 10.3 13.1 19.5 23.1 6.4 3.3 7.2 4.1 0.0 10.8 0.0 2.2 49.9 20.8 18.3 8.8 11.5 1.3 12.9 66.7 0.3 29.5 57.9 9.8 8.0 107.4 9.4 2.9 25.3 17.5 4.6 29.7 7.8 2.1 5.8 20.4 8.7 12.0 11.1 21.8 4.7 9.8 8.4 22.0 36.6 0.0 3.3 0.0 171.5 5.6 8.6 0.0 33.7 6.1 17.2 24.7 14.1 51.2 14.0 36.6 4.9 9.0 15.2 59.4 24.0 2.2 57.3 19.7 1.7 5.0 75.3 3.8 0.8 0.0 0.4 16.5 16.9 29.5 28.7 NOL7 "C6orf90, dJ223E5.2, NOP27, PQBP3, RARG-1" ENSG00000225921 "Nucleolar protein 7" Q9UMY1 6 13615335-13632739 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029185 Supported Supported "Nucleoli,Mitotic chromosome,Mitochondria" Yes Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Mitotic chromosome" Mitochondria "HPA029185: AB_10601274" "unprognostic (8.76e-2)" "unprognostic (8.94e-2)" "unprognostic (8.38e-2)" "unprognostic (1.15e-2)" "unprognostic (3.75e-1)" "unprognostic (5.77e-2)" "unprognostic (2.50e-3)" "unprognostic (1.57e-1)" "unprognostic (4.64e-2)" "prognostic favorable (3.64e-5)" "unprognostic (1.26e-1)" "unprognostic (2.03e-2)" "unprognostic (8.04e-3)" "unprognostic (2.58e-1)" "unprognostic (1.17e-1)" "unprognostic (4.86e-2)" "unprognostic (4.79e-2)" 44.3 43.9 29.5 21.7 30.8 29.5 42.0 32.2 34.0 37.5 28.2 44.8 26.8 37.7 23.4 38.2 35.5 16.6 48.2 28.7 31.1 58.5 37.9 32.2 25.8 30.9 31.4 40.7 48.9 40.2 35.9 21.1 31.0 35.1 19.8 16.6 38.0 19.2 44.5 36.9 36.4 16.0 30.8 37.8 37.9 41.7 30.7 15.2 37.1 17.1 20.3 41.4 34.9 33.8 71.7 37.2 31.7 42.7 26.9 26.1 74.4 71.8 29.3 48.4 44.4 60.0 24.9 97.8 137.4 34.4 57.7 46.5 46.9 42.4 47.8 57.5 105.0 91.2 36.3 104.0 45.4 112.0 61.4 25.5 41.5 42.5 24.2 29.8 33.6 45.5 135.7 22.2 44.7 38.1 70.6 147.6 42.1 37.0 74.1 74.4 46.8 140.5 57.9 21.7 92.5 60.3 40.9 88.0 94.9 36.2 53.6 42.8 65.7 48.0 51.9 57.8 108.3 66.2 123.2 100.2 30.7 70.7 75.6 34.5 59.6 82.1 59.2 76.4 68.2 104.0 84.7 71.4 73.2 87.8 90.7 69.0 27.4 61.9 82.9 91.4 96.0 67.9 29.5 30.8 32.2 34.0 28.7 31.1 30.9 31.4 31.0 30.8 30.7 33.8 103.1 93.0 73.5 10.4 112.5 90.8 117.3 151.0 50.1 62.1 78.9 97.0 214.9 68.6 112.0 57.0 22.9 137.4 71.5 72.7 123.3 188.7 202.3 105.8 95.0 109.2 37.1 89.4 14.0 261.2 153.8 90.9 58.1 91.6 90.6 67.0 61.1 61.8 115.1 48.8 17.1 97.8 130.2 52.6 81.8 38.9 82.6 78.5 101.4 8.4 119.7 124.2 78.2 13.6 19.0 175.0 94.3 79.4 138.8 121.7 81.2 163.6 135.6 61.7 65.7 92.5 119.4 186.3 112.9 70.8 90.5 155.3 99.5 99.2 91.0 117.2 NOLC1 "KIAA0035, NOPP130, NOPP140, P130, Srp40" ENSG00000166197 "Nucleolar and coiled-body phosphoprotein 1" Q14978 10 102152176-102163871 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032654, HPA037366, HPA050388" Supported Enhanced "Nucleoli fibrillar center" No Yes 44000 "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli fibrillar center" "CAB032654: AB_2152006, HPA037366: AB_10670930, HPA050388: AB_2681109" "unprognostic (3.23e-1)" "unprognostic (5.58e-2)" "unprognostic (9.44e-2)" "unprognostic (9.13e-2)" "unprognostic (8.89e-2)" "unprognostic (7.03e-3)" "unprognostic (2.36e-3)" "unprognostic (7.34e-3)" "unprognostic (3.43e-1)" "unprognostic (3.74e-1)" "unprognostic (5.64e-3)" "unprognostic (3.73e-2)" "prognostic unfavorable (9.19e-5)" "unprognostic (3.15e-2)" "unprognostic (3.73e-1)" "prognostic unfavorable (8.25e-5)" "unprognostic (7.68e-2)" 36.5 23.9 10.7 41.9 12.3 37.2 32.3 14.6 20.5 27.1 4.5 31.8 21.8 30.3 18.7 33.3 34.4 29.0 24.0 12.6 18.2 21.4 37.5 24.9 43.1 10.9 14.4 34.4 38.4 42.9 14.6 38.3 11.9 31.5 39.1 38.0 26.3 26.6 45.3 21.9 22.8 33.8 10.8 27.6 27.4 19.3 12.2 54.2 37.6 46.4 55.7 64.2 19.6 18.3 202.1 175.1 98.2 209.0 84.7 66.0 166.6 108.5 87.8 150.1 130.5 302.1 132.4 401.5 118.1 69.5 73.9 225.1 285.0 236.1 173.3 127.0 194.8 267.9 143.6 200.3 112.0 389.8 122.8 86.3 169.8 158.3 328.7 94.5 96.5 194.3 286.6 172.6 102.6 170.3 373.7 95.0 196.5 150.7 137.1 277.3 261.6 233.3 100.2 123.5 148.3 141.9 103.5 124.1 144.5 95.6 207.5 99.3 79.3 67.7 93.5 81.3 256.9 165.5 254.4 442.4 110.5 422.7 60.7 2.4 12.5 11.6 20.4 14.4 24.9 16.6 16.1 19.2 16.2 12.1 18.5 22.6 1.3 17.3 17.2 12.4 13.0 17.9 10.7 12.3 14.6 20.5 12.6 18.2 10.9 14.4 11.9 10.8 12.2 18.3 47.8 60.9 74.7 6.2 47.6 120.4 112.6 37.7 101.9 20.8 52.6 48.0 35.3 20.0 68.2 16.5 14.6 49.2 29.1 28.3 25.4 42.2 29.0 38.5 56.3 47.3 27.6 56.8 8.8 23.1 62.7 63.9 43.3 73.1 44.2 28.6 16.8 23.4 27.1 10.1 7.9 38.3 18.3 11.2 46.0 9.7 23.0 26.8 26.6 4.7 22.9 15.1 32.0 2.5 6.8 48.8 21.0 21.1 62.3 89.5 10.2 19.9 56.6 20.0 6.6 85.8 58.9 32.1 53.5 103.3 117.5 48.6 44.5 40.1 49.1 100.5 NOP58 "HSPC120, NOP5" ENSG00000055044 "NOP58 ribonucleoprotein" Q9Y2X3 2 202265736-202303661 "Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018472, HPA021062" Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center" NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoli fibrillar center" Nucleoplasm "HPA018472: AB_1854564, HPA021062: AB_1854565" "unprognostic (1.56e-2)" "unprognostic (1.61e-1)" "unprognostic (9.20e-2)" "unprognostic (2.15e-3)" "unprognostic (2.39e-1)" "unprognostic (3.94e-2)" "prognostic unfavorable (1.97e-6)" "unprognostic (6.64e-2)" "unprognostic (1.17e-2)" "prognostic favorable (9.86e-4)" "unprognostic (4.52e-3)" "unprognostic (5.20e-2)" "prognostic unfavorable (3.38e-9)" "unprognostic (1.79e-2)" "unprognostic (3.10e-1)" "unprognostic (1.33e-1)" "unprognostic (2.60e-1)" 36.0 35.1 33.5 43.9 33.6 76.3 43.7 38.8 58.4 29.5 33.4 30.4 28.2 32.2 33.4 37.8 31.6 23.6 25.1 33.4 36.3 32.8 40.7 26.4 60.3 32.3 33.3 37.4 37.8 24.8 30.2 32.6 32.6 29.5 35.8 28.1 26.5 23.1 41.8 30.7 29.7 27.3 32.6 33.9 29.6 24.9 34.8 41.9 27.1 21.5 59.8 43.3 30.2 35.3 126.4 86.0 85.1 106.8 62.0 55.6 199.2 118.5 62.9 89.1 82.9 191.5 110.9 193.1 95.4 72.5 111.6 114.0 170.1 144.7 158.4 75.0 152.5 233.6 133.3 193.7 91.5 234.7 108.6 72.1 85.3 124.6 284.6 48.6 81.2 112.3 260.4 144.1 113.4 131.4 215.1 258.7 212.9 139.4 146.5 179.5 128.3 257.1 107.1 148.5 130.5 95.8 109.0 156.6 140.8 136.2 106.4 181.8 70.3 113.5 133.8 102.5 206.0 115.7 226.1 274.8 84.2 163.7 138.5 13.4 24.0 7.4 37.2 35.6 55.0 56.1 53.1 51.2 37.4 45.0 57.5 58.9 2.3 52.1 28.3 53.1 58.0 32.5 33.5 33.6 38.8 58.4 33.4 36.3 32.3 33.3 32.6 32.6 34.8 35.3 56.3 109.0 116.2 22.2 111.6 85.8 150.5 98.0 78.0 28.1 53.8 70.2 82.7 37.1 116.8 40.5 41.7 78.1 87.1 35.7 29.4 59.9 39.2 59.6 75.9 62.3 35.2 65.2 39.0 67.8 96.9 82.6 51.0 97.0 137.3 47.7 32.2 46.1 47.7 25.2 47.5 61.5 61.1 23.2 43.5 11.1 43.2 51.5 24.9 20.6 59.6 18.8 35.0 20.6 27.0 50.3 17.3 29.7 118.6 89.9 18.3 37.8 70.6 44.2 26.3 112.2 116.8 70.4 58.4 77.5 74.7 68.0 124.1 45.4 79.6 94.6 NPM1 "B23, NPM" ENSG00000181163 "Nucleophosmin 1" P06748 5 171387116-171411810 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction" "Chaperone, RNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011384, CAB012983" Supported Enhanced "Nucleoplasm,Nucleoli rim" NA Yes 2000000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 32: Non-specific - Translation" "Nucleoli rim" Nucleoplasm "CAB012983: AB_2533084, HPA011384: AB_1854692" "unprognostic (1.84e-3)" "unprognostic (2.59e-1)" "unprognostic (2.23e-2)" "unprognostic (3.30e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (7.48e-4)" "prognostic unfavorable (4.82e-6)" "unprognostic (1.86e-2)" "unprognostic (5.25e-3)" "unprognostic (1.39e-1)" "unprognostic (2.26e-3)" "unprognostic (1.27e-1)" "prognostic unfavorable (2.89e-6)" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "unprognostic (1.52e-1)" "unprognostic (1.24e-2)" 515.1 370.6 180.7 468.4 190.3 789.2 597.1 188.6 233.5 759.2 195.9 486.6 347.1 656.6 421.5 623.0 596.1 355.4 336.7 169.0 210.7 375.3 370.3 364.5 777.0 196.2 188.6 1384.6 810.6 278.0 314.4 423.7 207.5 386.2 421.2 161.3 385.2 318.5 450.9 386.6 374.1 436.0 213.9 358.1 467.8 284.7 202.6 683.3 510.1 282.4 761.7 524.9 565.4 204.5 2476.2 1522.7 1864.0 2663.1 1073.3 1915.6 2736.9 2111.3 1826.0 2678.1 2387.2 3640.2 1622.2 6243.9 1683.2 1194.5 1927.6 1386.6 2552.2 4639.2 3423.4 2027.9 2027.3 2149.1 1361.9 2740.2 1593.2 4556.3 1790.7 1732.2 1559.7 1845.8 3572.3 2184.3 2019.4 1460.9 2712.8 1406.5 1945.5 2826.5 3071.1 3087.4 2400.7 1280.7 1857.2 2695.2 2051.7 3241.9 2306.9 1583.1 1433.8 1167.4 1210.6 2084.4 4091.0 1288.7 2513.8 2000.7 1289.5 916.7 2114.4 1082.5 3705.3 1161.5 2139.6 3702.2 1403.3 3561.5 1897.0 153.6 287.1 92.3 443.1 311.4 834.2 847.9 832.8 654.3 564.2 634.9 1189.9 973.4 38.0 656.2 264.4 516.8 782.6 1076.1 180.7 190.3 188.6 233.5 169.0 210.7 196.2 188.6 207.5 213.9 202.6 204.5 462.2 346.1 461.1 12.4 911.0 1400.1 1224.1 1692.5 993.1 177.2 779.0 1045.4 243.5 514.8 764.5 323.7 43.8 1647.8 615.9 175.3 743.4 1073.6 135.8 466.3 707.3 568.2 362.1 865.5 15.6 919.2 2021.0 685.9 489.8 544.6 443.8 688.8 383.8 254.1 1071.0 127.9 20.3 656.0 679.5 629.2 817.6 98.6 974.9 557.2 610.1 19.7 862.8 339.2 476.8 14.6 21.2 922.5 370.1 649.9 671.6 1051.5 404.2 911.0 357.4 144.1 433.9 617.8 1074.1 855.7 578.6 907.2 1019.1 1538.8 865.1 1019.5 866.2 967.3 NR1D1 "ear-1, hRev, Rev-ErbAalpha, REVERBA, REVERBalpha, THRA1, THRAL" ENSG00000126368 "Nuclear receptor subfamily 1 group D member 1" P20393 17 40092793-40100589 "Metabolic proteins, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 325.5" "Cell type enhanced" "Detected in all" "Squamous epithelial cells: 95.5;Suprabasal keratinocytes: 81.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 18.5" "Group enriched" "Detected in many" 6 "monocytes: 5.5;T-cells: 18.5" "Cell line enhanced" "Detected in all" "Karpas-707: 60.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007935 Uncertain Supported "Nuclear bodies" NA Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 2: Karpas-707 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear bodies" "HPA007935: AB_10601277" "unprognostic (1.38e-2)" "unprognostic (3.46e-2)" "prognostic unfavorable (1.94e-4)" "unprognostic (2.53e-1)" "unprognostic (2.24e-2)" "unprognostic (1.05e-1)" "unprognostic (4.50e-2)" "unprognostic (1.03e-1)" "prognostic favorable (1.36e-4)" "unprognostic (1.93e-3)" "unprognostic (9.93e-3)" "unprognostic (2.73e-1)" "unprognostic (9.15e-3)" "unprognostic (4.54e-3)" "unprognostic (2.49e-1)" "unprognostic (3.09e-1)" "unprognostic (1.34e-1)" 72.3 53.7 23.5 6.3 27.0 5.4 63.1 52.9 49.7 109.6 10.6 53.3 14.3 35.8 4.5 42.5 27.7 7.1 60.8 24.9 17.2 38.0 43.2 49.2 9.3 18.1 20.9 71.3 24.3 9.0 32.0 6.0 15.9 40.5 4.0 50.4 52.9 16.3 99.0 325.5 23.0 7.5 12.9 11.6 31.5 12.5 34.0 6.3 32.1 38.1 5.4 42.5 96.5 25.2 5.5 7.8 1.6 6.2 9.0 6.2 2.2 11.9 19.5 3.9 4.9 5.1 19.5 6.7 6.9 13.8 12.9 15.4 4.1 18.0 2.9 5.6 4.1 4.8 7.9 13.5 14.6 7.2 6.9 13.5 12.8 13.3 28.2 12.6 4.9 7.7 7.2 60.6 3.8 3.8 10.7 6.1 3.0 10.8 12.3 7.5 2.2 20.7 5.4 4.9 5.1 2.9 7.6 9.7 12.4 2.7 4.6 5.8 4.7 17.2 16.7 14.1 9.5 21.5 35.7 2.6 23.4 4.0 13.6 0.0 0.5 0.0 4.4 2.0 18.5 1.7 5.5 6.4 1.1 2.1 4.8 3.5 0.2 1.0 5.5 1.4 8.0 1.8 23.5 27.0 52.9 49.7 24.9 17.2 18.1 20.9 15.9 12.9 34.0 25.2 16.4 3.2 2.0 17.3 5.7 64.5 47.5 20.5 67.2 71.4 9.4 15.1 5.7 8.6 11.9 1.8 4.2 2.6 4.9 26.0 7.9 16.1 2.3 25.4 30.6 18.6 8.3 3.6 7.1 11.8 1.2 26.5 31.1 64.2 2.5 2.7 6.8 31.8 2.5 42.1 6.2 7.2 8.2 3.4 19.4 1.5 21.8 7.7 19.6 8.4 1.2 39.0 5.2 5.0 1.2 26.0 14.7 38.7 10.5 35.4 58.8 7.9 5.0 29.7 6.6 9.6 19.4 2.0 11.1 95.5 81.1 2.3 11.9 13.7 6.0 28.7 NR2F6 "EAR-2, EAR2, ERBAL2" ENSG00000160113 "Nuclear receptor subfamily 2 group F member 6" P10588 19 17231883-17245919 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 104.0" "Cell type enhanced" "Detected in all" "Distal enterocytes: 206.0;Hepatocytes: 148.4;Horizontal cells: 151.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 187.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB079917 Supported "Nuclear speckles,Cytosol" NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles" Cytosol "CAB079917: AB_2635238" "unprognostic (1.48e-1)" "unprognostic (1.30e-1)" "unprognostic (2.17e-1)" "prognostic unfavorable (4.36e-4)" "unprognostic (1.08e-1)" "unprognostic (1.12e-1)" "unprognostic (3.07e-1)" "unprognostic (3.67e-1)" "unprognostic (7.20e-2)" "unprognostic (1.02e-2)" "unprognostic (2.39e-1)" "unprognostic (6.62e-2)" "unprognostic (9.68e-2)" "unprognostic (1.31e-1)" "unprognostic (2.29e-2)" "unprognostic (7.28e-3)" "unprognostic (1.37e-3)" 17.0 21.8 19.3 5.0 16.9 1.2 17.7 15.8 22.8 18.8 23.8 39.4 31.2 19.8 14.3 47.4 19.1 2.9 39.0 16.8 20.2 32.8 104.0 17.5 1.7 23.9 21.4 12.1 44.6 10.4 22.0 13.1 18.6 25.3 9.3 6.6 28.0 9.8 27.9 23.9 25.4 4.5 17.5 9.9 38.6 14.3 20.4 1.8 21.6 9.9 2.7 25.5 22.2 15.6 65.0 38.1 20.3 37.2 7.9 8.8 187.2 35.7 12.9 15.2 13.1 26.1 55.5 15.2 108.8 16.0 8.9 31.9 15.6 20.5 6.7 20.4 90.0 13.9 24.4 47.3 17.3 6.7 18.8 11.6 23.2 7.0 11.3 15.9 9.5 6.8 33.3 3.7 6.7 34.7 5.9 24.7 55.8 48.1 58.5 11.6 12.7 13.2 21.2 41.3 16.3 46.7 19.9 68.7 43.1 19.6 38.2 21.1 15.8 10.7 26.1 20.6 28.8 21.0 7.9 10.9 13.1 9.9 13.4 0.0 0.6 1.1 1.7 0.0 1.4 0.3 2.3 1.5 1.1 2.3 3.8 1.3 0.1 4.6 0.1 0.5 2.4 0.8 19.3 16.9 15.8 22.8 16.8 20.2 23.9 21.4 18.6 17.5 20.4 15.6 21.2 9.6 22.9 6.8 4.7 10.6 14.1 12.8 11.4 71.9 65.9 54.7 36.4 34.3 20.8 25.8 77.2 65.4 3.7 206.0 29.4 23.2 13.3 51.7 32.5 20.8 46.0 4.4 7.2 47.8 65.3 17.6 47.4 60.0 1.3 26.1 15.0 148.4 16.3 151.4 7.6 80.2 24.4 4.7 4.6 6.0 17.7 5.2 10.6 8.4 2.4 45.7 1.0 6.6 5.8 50.4 78.5 18.8 1.2 23.2 72.3 30.2 25.9 54.3 6.6 17.3 24.5 1.6 9.0 24.3 10.5 79.8 4.2 44.3 75.3 18.2 NXPH2 NPH2 ENSG00000144227 "Neurexophilin 2" O95156 2 138669157-138780390 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.1;kidney: 4.1;ovary: 8.1" "Cell type enriched" "Detected in some" 6 "Inhibitory neurons: 156.1" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Group enriched" "Detected in many" 6 "medulla oblongata: 11.7;midbrain: 7.6;pons: 13.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 3.4;SiHa: 3.0;SuSa: 2.1;U-2 OS: 4.7;U-251 MG: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA034759 Approved "Secreted in brain" NA Yes "Cluster 73: Brain - Neuropeptide signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA034759: AB_10669732" "unprognostic (5.83e-2)" "unprognostic (8.83e-2)" "unprognostic (1.41e-1)" "unprognostic (2.72e-1)" "unprognostic (1.80e-1)" 0.2 0.0 1.8 0.1 1.7 0.0 0.1 1.0 1.8 0.1 0.2 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.0 1.0 0.4 4.1 0.0 0.0 0.0 11.7 7.6 8.1 0.0 0.0 0.1 0.1 13.1 0.0 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.9 0.6 3.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 4.7 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.7 1.0 1.8 1.0 0.4 11.7 7.6 13.1 1.9 1.1 1.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 156.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.5 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OIP5 "CT86, hMIS18beta, MIS18B" ENSG00000104147 "Opa interacting protein 5" O43482 15 41309273-41332591 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.3;skeletal muscle: 10.3;testis: 20.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 45.9;Extravillous trophoblasts: 24.0;Spermatocytes: 110.6;Spermatogonia: 56.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA052271, HPA059602" Enhanced Supported "Nuclear speckles,Vesicles" NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" Vesicles "HPA052271: AB_2681780, HPA059602: AB_2684079" "unprognostic (5.17e-2)" "unprognostic (7.26e-2)" "unprognostic (3.07e-1)" "unprognostic (1.59e-2)" "unprognostic (6.94e-2)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.79e-4)" "prognostic unfavorable (2.26e-4)" "unprognostic (2.71e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (9.34e-5)" "unprognostic (5.51e-2)" "unprognostic (0.00e+0)" "unprognostic (3.84e-2)" "unprognostic (2.02e-1)" "unprognostic (5.75e-2)" "unprognostic (2.86e-2)" 0.6 1.7 0.1 3.3 0.2 10.3 1.2 1.2 0.4 0.9 0.2 4.1 3.5 0.8 0.3 3.8 0.4 0.6 1.5 0.2 0.2 0.3 1.2 0.5 5.8 0.2 0.4 1.5 0.3 0.1 0.1 2.3 0.4 0.5 3.9 0.7 0.8 0.6 10.3 3.3 3.9 1.1 0.1 1.7 1.5 20.9 0.2 9.1 0.4 0.8 5.2 0.7 1.3 0.5 33.7 17.8 34.3 24.9 1.7 2.1 32.4 20.0 9.3 24.5 26.1 31.8 16.2 19.8 17.0 7.7 37.8 51.0 35.7 16.1 19.2 42.4 40.1 42.4 49.8 33.6 0.4 46.5 22.1 0.7 3.2 13.8 14.5 5.2 21.1 40.8 59.4 37.3 16.5 16.3 27.1 34.8 30.9 50.4 37.9 32.9 28.4 30.5 11.1 15.4 53.7 17.5 33.7 34.3 9.6 13.7 33.7 26.3 10.0 24.5 37.3 24.6 36.6 17.0 83.2 71.1 7.1 56.5 35.9 0.0 0.4 0.5 0.2 0.7 0.8 1.0 0.7 0.8 0.7 1.2 1.3 0.8 0.0 1.2 0.4 4.1 3.1 0.8 0.1 0.2 1.2 0.4 0.2 0.2 0.2 0.4 0.4 0.1 0.2 0.5 0.2 0.0 0.5 1.0 2.7 4.1 0.9 3.6 1.2 0.0 1.1 2.2 0.2 0.0 1.8 0.0 0.0 15.0 1.7 2.3 0.0 0.4 12.0 1.9 0.6 0.9 0.0 45.9 2.2 0.4 24.0 1.7 5.1 1.1 1.3 5.2 0.0 0.8 7.5 0.0 2.1 3.0 8.2 2.2 1.8 10.8 0.9 1.2 0.0 0.0 0.6 1.1 2.1 1.5 2.5 0.2 0.5 1.2 10.9 0.4 0.9 0.3 0.0 0.3 6.6 1.0 1.1 110.6 56.8 8.3 2.4 3.8 1.2 2.1 7.6 0.9 ORC1 "HSORC1, ORC1L, PARC1" ENSG00000085840 "Origin recognition complex subunit 1" Q13415 1 52372829-52404423 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 29.0;lymphoid tissue: 11.6" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 5.5;Early spermatids: 5.6;Erythroid cells: 14.1;Extravillous trophoblasts: 9.9;Plasma cells: 6.3;Spermatogonia: 6.5" "Cancer enhanced" "Detected in many" "testis cancer: 15.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "NK-cell: 3.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA027439, HPA027450" Approved Supported Nucleoplasm NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA027439: , HPA027450: AB_10602041" "unprognostic (3.28e-1)" "unprognostic (4.42e-3)" "prognostic favorable (1.74e-5)" "unprognostic (1.29e-2)" "unprognostic (7.29e-2)" "unprognostic (2.34e-3)" "prognostic unfavorable (3.22e-5)" "unprognostic (3.77e-3)" "prognostic unfavorable (3.69e-4)" "unprognostic (3.86e-2)" "unprognostic (2.70e-3)" "unprognostic (8.39e-2)" "unprognostic (1.25e-10)" "unprognostic (4.56e-3)" "unprognostic (1.05e-1)" "unprognostic (2.45e-1)" "unprognostic (1.57e-2)" 0.4 0.6 0.2 3.5 0.1 29.0 1.1 0.6 0.2 0.6 0.0 3.4 1.7 0.6 0.1 2.7 0.3 0.4 0.2 0.1 0.2 0.5 0.6 0.6 6.7 0.3 0.0 0.5 0.3 0.3 0.3 1.9 0.2 0.4 4.0 1.0 0.6 0.1 0.5 2.0 2.3 0.9 0.0 2.0 1.0 5.2 0.2 11.6 0.3 0.1 7.7 0.9 1.0 0.3 19.3 20.8 33.0 21.7 0.8 2.7 31.8 13.5 12.2 38.9 40.0 25.8 10.7 44.2 11.6 8.5 17.8 25.9 48.9 16.9 33.8 19.0 28.1 53.2 30.2 25.8 0.2 71.9 29.2 1.4 0.8 38.1 4.3 2.7 11.7 27.6 63.0 20.9 12.8 14.4 56.9 34.0 73.1 11.7 29.5 60.2 51.3 43.1 6.8 25.0 18.5 15.6 31.0 18.8 10.3 30.5 10.2 28.7 5.4 15.8 22.5 24.9 34.0 10.9 31.1 54.4 15.6 52.6 19.5 0.0 0.1 0.0 0.2 0.1 0.2 0.2 0.4 0.4 0.6 0.8 0.1 0.3 0.4 3.4 0.2 0.0 1.2 0.3 0.2 0.1 0.6 0.2 0.1 0.2 0.3 0.0 0.2 0.0 0.2 0.3 0.6 0.0 0.0 0.3 1.7 0.9 0.3 0.4 1.2 0.7 0.7 1.1 0.5 0.0 0.1 0.0 0.0 5.5 0.7 1.2 0.0 0.3 5.6 0.5 0.6 0.5 0.0 14.1 0.7 0.2 9.9 0.7 0.5 0.6 0.0 2.8 0.0 0.2 2.9 0.0 0.7 1.3 0.0 0.3 0.4 3.8 0.6 0.6 0.0 1.0 0.3 0.2 0.0 0.5 0.5 0.2 0.8 0.4 6.3 0.2 0.2 3.9 0.1 0.9 0.0 0.6 0.7 4.1 6.5 2.5 1.1 1.8 1.1 0.9 3.7 0.4 PAK4 ENSG00000130669 "P21 (RAC1) activated kinase 4" O96013 19 39125770-39182816 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "A549: 154.7;MCF7: 172.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025747, CAB044670, HPA070175, HPA072220" Uncertain Supported "Plasma membrane,Cell Junctions" NA Yes "Cluster 26: Non-specific - Mitochondria" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Plasma membrane, Cell Junctions" "CAB025747: , CAB044670: AB_1854940, HPA070175: AB_2686232, HPA072220: AB_2686497" "unprognostic (1.71e-1)" "unprognostic (2.84e-1)" "unprognostic (5.86e-2)" "unprognostic (2.84e-2)" "unprognostic (1.93e-1)" "unprognostic (8.51e-2)" "unprognostic (3.56e-3)" "unprognostic (1.13e-3)" "unprognostic (3.90e-2)" "unprognostic (4.04e-2)" "unprognostic (7.29e-2)" "prognostic unfavorable (9.85e-4)" "prognostic favorable (5.29e-5)" "unprognostic (2.39e-1)" "unprognostic (7.05e-2)" "unprognostic (2.02e-1)" "unprognostic (4.85e-2)" 11.6 20.0 16.7 8.1 18.2 5.3 22.1 14.2 18.4 27.2 14.0 30.2 27.4 20.6 9.4 43.9 23.4 7.5 15.5 13.9 13.4 37.2 26.2 39.6 4.5 17.1 17.2 24.2 31.8 16.2 30.5 16.3 15.8 40.7 8.0 5.8 42.4 11.0 14.0 40.4 25.1 5.7 12.0 13.8 25.3 35.0 15.7 5.4 29.3 4.3 5.4 20.2 30.4 17.0 62.8 154.7 22.7 34.8 7.1 7.5 68.1 29.3 11.7 19.3 19.4 102.1 51.9 14.3 43.3 18.7 25.2 22.7 12.6 23.2 7.2 38.0 35.4 16.9 27.5 50.4 11.3 17.5 23.6 9.0 10.2 18.1 12.9 12.6 25.5 21.4 34.3 11.0 11.8 172.7 18.6 18.9 41.4 55.2 36.7 18.5 17.9 10.9 19.0 67.9 72.2 49.9 29.8 130.6 33.6 11.7 58.1 28.4 42.8 32.6 55.6 37.8 53.0 12.3 12.9 11.9 39.9 10.3 39.9 0.3 0.7 1.2 0.6 0.3 0.8 0.5 0.7 1.1 0.9 0.6 0.5 0.5 0.5 0.9 0.6 0.8 0.9 0.7 16.7 18.2 14.2 18.4 13.9 13.4 17.1 17.2 15.8 12.0 15.7 17.0 5.1 0.0 1.5 9.4 3.9 14.4 15.9 13.8 9.6 18.8 34.2 21.7 2.0 20.0 9.1 18.4 25.0 42.6 4.4 47.5 31.3 20.5 4.1 19.5 8.5 15.0 44.9 5.0 3.9 19.7 67.4 8.8 23.9 23.3 5.7 21.6 10.0 13.3 9.6 21.9 4.2 33.8 28.5 5.3 4.1 6.4 11.8 3.6 7.2 8.4 11.2 13.6 8.2 9.5 13.5 21.8 44.2 10.5 5.8 21.7 39.5 14.4 13.7 13.4 0.0 8.5 7.5 10.4 24.0 20.1 18.8 65.4 6.0 22.3 33.9 24.3 PAQR4 FLJ30002 ENSG00000162073 "Progestin and adipoQ receptor family member 4" Q8N4S7 16 2969270-2973484 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 124.5;retina: 63.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 58.4;Oligodendrocytes: 62.0;Rod photoreceptor cells: 153.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "non-classical monocyte: 3.6" "Lineage enriched" "Detected in single" 9 "monocytes: 3.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA068394 Approved Vesicles NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 25: RPMI-8226 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Vesicles "HPA068394: AB_2685980" "unprognostic (1.93e-1)" "unprognostic (2.75e-1)" "unprognostic (6.73e-2)" "unprognostic (1.30e-3)" "unprognostic (8.39e-2)" "unprognostic (3.00e-2)" "prognostic unfavorable (6.86e-4)" "unprognostic (2.62e-2)" "unprognostic (7.59e-2)" "unprognostic (9.65e-3)" "unprognostic (5.21e-2)" "unprognostic (8.59e-2)" "prognostic unfavorable (3.01e-6)" "prognostic favorable (1.70e-4)" "unprognostic (1.36e-1)" "unprognostic (3.79e-2)" "unprognostic (6.06e-3)" 4.3 8.1 54.4 6.9 80.8 15.7 4.3 80.0 65.3 3.6 32.7 6.5 6.2 2.3 0.5 11.3 3.7 6.9 9.3 55.1 56.4 3.9 3.4 7.9 8.7 93.0 77.4 0.7 11.9 38.4 2.1 2.6 85.9 11.8 5.6 63.7 22.7 1.4 17.6 16.1 6.3 3.5 68.1 7.9 10.5 3.2 74.6 11.0 3.3 27.9 10.3 2.5 4.6 124.5 36.9 30.9 34.4 49.5 5.6 10.0 11.3 13.9 16.6 24.9 23.5 18.8 38.3 36.8 18.3 16.1 17.5 50.8 36.1 21.7 10.4 38.8 16.3 11.5 63.6 25.4 0.6 24.1 39.2 2.4 11.3 13.5 3.5 12.6 16.7 30.7 22.5 95.6 21.7 73.8 35.1 25.8 29.1 55.3 21.6 69.5 45.0 117.6 17.5 12.4 77.3 36.0 51.2 48.5 37.3 4.6 51.6 37.2 10.3 43.0 26.3 20.0 19.8 42.2 30.7 49.3 19.1 32.4 48.4 0.0 0.4 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 3.6 0.2 0.0 0.3 54.4 80.8 80.0 65.3 55.1 56.4 93.0 77.4 85.9 68.1 74.6 124.5 4.8 0.0 0.0 13.4 2.0 3.1 1.6 2.6 2.2 14.9 5.2 5.2 1.1 12.8 7.8 0.0 58.4 2.2 2.0 5.1 0.0 5.2 0.8 3.0 1.5 4.5 4.2 12.6 8.9 11.3 8.9 2.0 2.6 5.2 2.5 4.6 3.9 0.3 13.3 6.7 4.5 5.5 6.1 7.6 4.6 3.6 0.6 7.2 5.4 2.8 2.2 27.8 2.1 4.5 62.0 9.5 2.5 0.0 5.5 5.0 2.2 1.0 11.0 153.4 0.0 0.3 3.5 1.5 6.3 4.1 5.1 0.5 1.8 1.0 10.9 1.0 PASK "KIAA0135, PASKIN, STK37" ENSG00000115687 "PAS domain containing serine/threonine kinase" Q96RG2 2 241106099-241150264 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.8;lymphoid tissue: 22.9" "Cell type enhanced" "Detected in many" "Peritubular cells: 24.5;Theca cells: 26.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 19.8" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA016450, HPA021079" Uncertain Supported Cytosol NA Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 14: REH - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA016450: AB_1854992, HPA021079: AB_1854993" "unprognostic (1.76e-2)" "unprognostic (1.29e-2)" "unprognostic (2.84e-1)" "unprognostic (1.41e-2)" "unprognostic (1.14e-1)" "unprognostic (8.99e-6)" "unprognostic (1.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.60e-3)" "unprognostic (1.58e-2)" "unprognostic (1.02e-2)" "unprognostic (6.35e-2)" "unprognostic (7.12e-2)" "unprognostic (1.52e-3)" "unprognostic (1.68e-1)" "unprognostic (6.44e-2)" "unprognostic (4.38e-3)" 1.6 1.1 3.7 7.1 19.8 8.8 2.1 1.0 5.3 2.5 3.1 2.4 3.4 2.1 3.9 3.3 6.1 2.0 1.1 2.7 1.7 3.7 1.4 3.2 13.7 1.9 1.9 1.9 3.6 2.4 4.6 1.0 1.8 10.0 2.3 11.9 2.9 1.4 0.8 4.1 4.5 1.2 0.3 4.1 3.0 16.1 3.2 22.9 5.1 0.2 7.8 2.1 2.2 5.2 7.4 9.9 12.9 16.7 1.1 1.9 17.4 7.0 2.2 6.3 8.8 8.1 7.4 3.8 1.4 1.5 13.8 17.9 15.1 6.1 4.6 15.6 13.8 10.6 19.1 14.4 0.8 14.7 16.0 0.9 4.7 6.5 1.9 2.6 4.6 16.2 14.0 5.2 4.5 8.0 17.5 15.4 14.6 8.8 5.9 27.5 13.3 4.7 2.5 16.0 23.1 7.0 3.9 8.0 3.2 6.8 6.7 10.5 6.1 8.8 7.7 11.1 9.6 6.8 7.4 18.1 5.4 10.9 8.2 4.4 0.6 0.5 1.0 0.4 0.9 4.5 3.9 3.5 0.8 3.9 2.3 2.6 0.8 1.9 0.7 0.4 4.1 2.2 3.7 19.8 1.0 5.3 2.7 1.7 1.9 1.9 1.8 0.3 3.2 5.2 2.3 3.2 7.9 2.6 8.5 2.7 1.2 1.6 2.2 2.6 3.5 4.3 3.1 2.8 1.9 3.7 4.2 0.9 2.2 3.1 0.0 1.5 14.9 13.9 1.6 8.5 0.0 13.3 12.5 2.0 1.7 2.7 3.6 4.4 3.8 11.7 17.5 1.5 2.0 1.7 6.1 3.5 0.0 4.7 2.0 3.5 5.9 2.1 12.4 3.7 2.7 2.1 7.2 0.5 2.6 0.9 1.0 24.5 4.7 1.7 1.9 1.4 12.3 18.7 0.0 2.1 2.1 16.1 12.7 2.6 1.4 0.3 19.1 26.5 3.9 0.9 PCNA ENSG00000132646 "Proliferating cell nuclear antigen" P12004 20 5114953-5126626 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Host-virus interaction" DNA-binding "Cancer-related genes, Deafness, Disease variant, Dwarfism, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 383.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000148, HPA030521, HPA030522, HPA030523" Enhanced Enhanced Nucleoplasm No Yes 170000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB000148: AB_628110, HPA030521: AB_10600218, HPA030522: AB_10602096, HPA030523: AB_10602199" "unprognostic (5.21e-2)" "prognostic favorable (1.86e-5)" "unprognostic (2.96e-2)" "unprognostic (2.43e-1)" "unprognostic (3.17e-1)" "unprognostic (5.60e-3)" "prognostic unfavorable (2.61e-4)" "unprognostic (1.47e-2)" "unprognostic (2.22e-1)" "unprognostic (3.89e-2)" "unprognostic (1.01e-2)" "unprognostic (9.78e-2)" "prognostic unfavorable (3.03e-6)" "unprognostic (2.12e-2)" "unprognostic (2.29e-1)" "unprognostic (7.11e-3)" "unprognostic (7.46e-2)" 31.2 47.2 23.2 85.2 26.0 383.2 51.0 26.8 29.7 41.5 26.8 89.0 70.7 38.1 30.9 81.2 39.1 34.8 30.6 23.0 24.4 43.7 55.3 37.5 168.8 25.1 24.0 37.7 32.8 42.4 25.1 69.8 26.0 32.2 93.7 94.1 40.3 38.3 27.9 62.8 72.9 47.9 26.8 54.0 53.9 62.3 23.3 219.9 42.0 26.8 137.3 51.0 42.3 30.0 769.1 591.4 585.0 253.7 136.1 126.6 409.5 491.6 288.3 453.7 640.0 465.3 594.2 773.4 155.7 177.5 395.2 558.8 350.7 594.4 413.2 231.7 386.8 543.7 207.8 1098.3 57.8 753.7 233.0 92.6 138.2 387.2 91.7 95.3 263.3 503.6 493.9 631.2 449.7 278.3 1450.6 829.3 439.9 592.0 322.9 787.9 514.1 622.5 208.5 441.1 500.8 339.4 345.1 524.6 351.9 213.9 371.2 378.0 177.2 324.3 373.3 461.5 572.0 317.2 981.6 1313.9 145.9 707.4 426.2 5.0 23.2 18.5 36.5 23.3 45.7 33.5 45.7 37.1 32.6 29.2 41.6 37.3 7.7 43.6 24.7 29.9 48.1 36.7 23.2 26.0 26.8 29.7 23.0 24.4 25.1 24.0 26.0 26.8 23.3 30.0 32.4 44.8 26.0 2.9 40.6 67.7 44.4 121.4 44.3 42.1 27.5 45.2 14.5 21.5 60.5 58.8 27.1 171.5 44.3 42.9 60.7 51.6 176.0 30.2 21.4 34.8 19.9 189.0 4.3 39.6 175.6 38.7 21.9 27.7 22.7 53.1 29.6 27.1 96.7 32.0 5.9 53.9 75.3 24.2 33.4 109.1 36.1 32.7 37.4 3.7 47.6 74.0 23.7 4.0 13.5 28.3 20.3 40.3 56.6 23.3 33.3 46.1 44.1 97.1 52.6 29.2 46.1 149.1 101.1 65.5 49.7 66.4 48.6 29.6 84.5 40.4 PES1 "NOP7, PES" ENSG00000100029 "Pescadillo ribosomal biogenesis factor 1" O00541 22 30576625-30607083 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040210, HPA062439, HPA066670" Supported Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA040210: AB_2676885, HPA062439: AB_2684764, HPA066670: AB_2685700" "unprognostic (1.82e-1)" "unprognostic (5.88e-2)" "unprognostic (5.59e-3)" "unprognostic (4.83e-2)" "unprognostic (1.48e-1)" "unprognostic (3.23e-3)" "prognostic unfavorable (1.84e-9)" "unprognostic (3.29e-2)" "unprognostic (3.40e-1)" "unprognostic (1.73e-1)" "unprognostic (4.79e-2)" "unprognostic (2.46e-2)" "unprognostic (5.65e-2)" "unprognostic (1.27e-3)" "unprognostic (1.65e-1)" "unprognostic (4.56e-2)" "unprognostic (1.42e-1)" 33.3 41.0 26.3 29.2 28.6 35.5 32.2 26.7 30.5 31.8 27.1 29.6 21.7 35.5 21.2 43.6 29.4 20.2 28.8 26.9 26.2 38.7 48.2 26.2 32.3 27.1 27.2 34.2 57.3 30.1 21.8 21.5 27.6 32.9 19.6 9.2 29.3 21.5 48.8 45.3 28.2 22.5 25.8 34.4 35.7 40.0 27.0 23.8 27.1 20.0 27.3 35.0 31.9 30.0 132.2 146.6 53.0 113.7 59.9 58.4 81.6 84.7 69.6 141.6 110.0 170.6 55.2 177.2 74.4 97.0 110.3 89.4 163.9 153.5 103.1 76.4 159.8 85.9 80.8 149.0 149.3 209.6 86.8 82.7 94.7 148.3 147.3 68.3 93.0 62.4 144.6 69.9 87.7 164.3 102.6 209.8 103.1 128.3 106.7 129.0 91.7 173.3 78.9 88.7 91.4 94.6 84.2 94.6 117.8 42.0 66.8 106.1 74.2 165.9 126.1 85.3 145.1 88.1 81.0 178.6 116.2 94.9 109.0 7.5 24.9 6.4 18.9 29.8 23.2 20.2 17.4 18.1 26.8 20.0 19.4 18.0 0.9 20.0 22.3 23.2 14.3 29.3 26.3 28.6 26.7 30.5 26.9 26.2 27.1 27.2 27.6 25.8 27.0 30.0 23.6 3.2 18.9 4.9 17.4 22.6 23.4 32.7 22.2 6.5 14.1 12.2 3.8 24.3 22.1 25.8 8.4 34.9 7.8 19.6 25.4 48.0 44.4 11.7 13.8 23.2 23.4 24.6 4.3 43.9 40.0 15.4 22.4 10.6 18.3 24.4 27.8 22.8 38.4 3.3 4.3 22.4 22.4 27.8 12.6 14.3 19.9 21.2 21.4 2.8 29.0 13.5 16.5 6.6 5.1 38.7 16.2 20.3 28.3 26.4 31.3 55.1 24.6 8.9 19.7 23.2 20.7 28.7 20.9 25.9 22.9 28.5 13.5 19.9 29.7 15.1 PGAP4 "C9orf125, MGC12992, TMEM246" ENSG00000165152 "Post-GPI attachment to proteins GalNAc transferase 4" Q9BRR3 9 101473170-101533537 "Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 16 "Cardiomyocytes: 52.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 25.5;hTERT-RPE1: 28.8;OE19: 48.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011318, HPA054041" Uncertain Approved Mitochondria NA Yes "Cluster 45: Intestine - Brush border" "Cluster 21: OE19 - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA011318: AB_2668482, HPA054041: AB_2682353" "unprognostic (2.58e-2)" "unprognostic (4.76e-2)" "unprognostic (5.52e-1)" "unprognostic (2.81e-3)" "unprognostic (2.72e-2)" "unprognostic (9.15e-2)" "unprognostic (1.20e-3)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "unprognostic (4.24e-1)" "unprognostic (3.51e-2)" "unprognostic (2.09e-1)" "prognostic favorable (1.55e-8)" "unprognostic (1.62e-1)" "unprognostic (1.91e-1)" "unprognostic (2.50e-1)" "unprognostic (9.16e-2)" 3.9 10.3 21.5 2.2 21.3 0.5 2.4 18.9 26.2 16.6 4.5 13.4 8.4 7.1 3.7 14.4 13.7 6.8 30.4 24.9 26.1 4.7 2.4 5.4 0.4 17.9 13.4 19.5 11.1 16.6 12.3 0.6 26.1 6.9 11.2 9.9 6.1 9.4 4.8 12.0 7.6 6.7 9.6 1.6 16.0 2.8 19.2 0.9 4.2 6.1 2.4 6.4 11.9 20.3 0.0 14.6 11.3 0.0 0.3 0.2 0.0 9.8 14.1 7.0 13.8 0.7 7.8 0.0 3.2 17.9 0.8 23.1 0.0 16.1 4.2 0.0 5.8 8.1 10.3 0.0 0.5 0.0 0.0 6.2 25.5 0.0 3.8 28.8 0.1 0.0 0.0 0.0 14.3 0.0 0.0 0.0 14.0 48.1 0.0 0.0 5.7 0.0 10.5 2.7 18.9 17.8 5.5 0.0 0.0 2.7 0.0 13.8 0.0 10.7 6.6 0.0 0.0 1.0 0.0 0.0 15.2 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.5 21.3 18.9 26.2 24.9 26.1 17.9 13.4 26.1 9.6 19.2 20.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PGGHG "ATHL1, FLJ22635" ENSG00000142102 "Protein-glucosylgalactosylhydroxylysine glucosidase" Q32M88 11 289126-296107 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "pancreas: 657.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 160.3;Alveolar cells type 2: 81.8;Breast glandular cells: 35.1;Club cells: 31.6;Collecting duct cells: 33.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "JURKAT: 132.8;U-266/70: 34.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA039383, HPA058829" Uncertain Enhanced Cytosol NA Yes "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 25: Pancreas - Digestion" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" Cytosol "HPA039383: AB_10796225, HPA058829: AB_2683830" "unprognostic (1.40e-3)" "unprognostic (2.18e-1)" "unprognostic (4.22e-2)" "unprognostic (2.37e-1)" "unprognostic (1.36e-2)" "unprognostic (5.83e-2)" "unprognostic (7.95e-3)" "unprognostic (2.77e-2)" "unprognostic (2.16e-2)" "unprognostic (2.14e-2)" "unprognostic (2.71e-2)" "unprognostic (3.45e-1)" "unprognostic (1.92e-3)" "unprognostic (2.85e-3)" "unprognostic (1.09e-2)" "unprognostic (1.22e-1)" "prognostic favorable (5.12e-4)" 25.3 5.6 5.8 41.6 5.8 16.3 41.9 5.5 25.6 56.0 6.8 25.2 50.5 21.6 32.7 14.1 34.6 18.9 18.8 5.4 5.8 116.4 77.8 67.0 63.5 6.9 6.4 8.7 657.7 2.9 12.5 7.3 8.2 34.6 6.3 0.6 36.2 46.1 4.5 8.6 103.0 3.0 5.7 101.9 18.5 6.3 7.1 37.4 74.4 3.2 17.6 21.5 22.6 6.3 5.4 5.8 10.5 11.7 4.2 3.7 8.2 4.2 3.4 2.4 2.1 5.0 15.0 0.0 5.3 5.1 5.1 3.3 0.9 1.9 0.3 13.3 4.0 2.5 4.2 6.8 5.3 0.3 22.8 13.8 1.5 0.9 0.7 8.9 8.1 132.8 10.5 15.9 1.3 7.7 24.0 12.1 8.3 1.8 1.0 21.5 2.1 7.8 5.6 1.8 0.1 2.4 1.5 7.8 7.2 4.6 5.7 2.9 7.5 4.9 7.0 1.5 0.5 34.8 1.0 6.0 0.8 4.3 5.8 1.2 0.7 1.0 6.1 3.2 5.1 1.5 1.0 3.3 0.5 1.5 2.1 4.5 3.7 5.6 2.5 2.0 0.1 2.2 5.8 5.8 5.5 25.6 5.4 5.8 6.9 6.4 8.2 5.7 7.1 6.3 17.8 160.3 81.8 0.0 9.1 0.0 0.0 0.0 0.0 0.0 35.1 26.8 0.0 0.0 31.6 33.1 0.0 0.3 29.8 0.0 0.0 4.9 0.0 12.5 12.0 4.5 0.0 0.0 0.0 8.3 3.3 4.2 0.0 17.6 6.3 1.5 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 1.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 16.1 0.0 0.0 2.9 10.2 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.3 14.4 0.9 0.0 0.0 PIGW "FLJ37433, Gwt1" ENSG00000277161 "Phosphatidylinositol glycan anchor biosynthesis class W" Q7Z7B1 17 36534987-36539310 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Acyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023499 Approved "Plasma membrane" No Yes "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane" "HPA023499: " "unprognostic (4.96e-3)" "unprognostic (3.84e-2)" "unprognostic (5.40e-3)" "unprognostic (7.39e-2)" "unprognostic (2.32e-1)" "unprognostic (7.71e-2)" "unprognostic (8.14e-3)" "unprognostic (1.05e-1)" "unprognostic (1.89e-1)" "unprognostic (4.62e-2)" "unprognostic (1.98e-1)" "unprognostic (3.29e-1)" "unprognostic (1.73e-2)" "unprognostic (1.41e-1)" "unprognostic (8.96e-2)" "unprognostic (1.08e-3)" "unprognostic (1.88e-1)" 4.5 3.8 1.0 3.9 1.1 2.7 3.9 1.4 1.5 3.2 1.8 4.3 2.6 4.2 2.0 7.4 3.4 1.9 3.7 1.0 1.5 6.5 6.5 3.7 3.8 1.5 1.2 2.5 4.7 2.6 4.0 2.0 1.5 3.3 3.6 1.8 5.0 1.3 8.2 5.8 4.3 2.6 1.1 4.4 4.5 2.8 1.4 2.1 4.1 3.4 3.5 3.6 4.3 1.3 10.8 15.2 9.0 9.2 4.9 4.2 15.0 11.6 6.2 12.2 9.3 11.7 12.2 19.9 3.8 7.9 14.9 15.7 16.5 8.0 16.1 11.3 23.3 14.7 7.3 11.0 3.8 32.2 17.2 5.2 9.6 12.5 5.4 2.5 7.9 6.3 26.9 9.5 8.9 10.1 16.4 11.2 16.5 7.5 13.0 15.3 24.0 18.8 7.6 11.6 20.7 16.7 21.0 8.6 9.3 8.4 27.8 4.7 10.4 21.7 29.1 20.8 26.1 8.8 32.8 22.0 5.2 18.0 19.6 0.8 1.7 0.3 2.0 2.7 2.8 1.5 2.6 2.1 3.5 2.9 3.2 3.1 0.4 2.6 3.5 2.1 1.6 2.2 1.0 1.1 1.4 1.5 1.0 1.5 1.5 1.2 1.5 1.1 1.4 1.3 3.6 3.2 3.1 1.6 4.6 3.4 9.5 4.6 12.5 2.2 4.3 2.9 1.6 10.0 4.2 0.0 0.0 6.1 5.4 2.9 7.9 6.8 0.2 2.4 3.6 4.7 1.2 12.6 2.0 6.4 6.7 3.8 5.1 2.7 0.0 2.3 1.1 6.0 4.5 3.3 2.6 4.0 0.0 3.3 2.2 0.6 2.8 3.5 0.0 0.0 3.1 4.2 1.0 1.5 2.5 7.1 3.6 2.2 4.9 10.2 1.0 4.9 2.8 3.1 0.0 3.7 3.6 3.4 7.4 9.4 6.8 4.1 3.1 3.5 5.6 5.3 PIK3IP1 "HGFL, MGC17330, TrIP" ENSG00000100100 "Phosphoinositide-3-kinase interacting protein 1" Q96FE7 22 31281594-31292534 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "T-cells: 143.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive CD4 T-cell: 499.2" "Lineage enriched" "Detected in all" 6 "T-cells: 499.2" "Cell line enhanced" "Detected in many" "RT4: 24.1;SK-BR-3: 26.1;U-698: 34.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA Yes 6800000 "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.02e-1)" "unprognostic (1.97e-3)" "unprognostic (1.58e-1)" "unprognostic (4.84e-2)" "unprognostic (8.19e-2)" "unprognostic (1.61e-3)" "unprognostic (5.78e-2)" "unprognostic (1.63e-3)" "unprognostic (2.82e-1)" "unprognostic (1.40e-1)" "unprognostic (1.99e-1)" "unprognostic (9.95e-3)" "unprognostic (1.28e-2)" "unprognostic (2.65e-3)" "unprognostic (4.42e-2)" "unprognostic (8.68e-2)" "prognostic favorable (3.80e-4)" 51.2 41.7 35.4 59.3 42.5 41.7 39.5 38.3 40.2 21.4 23.7 35.5 17.5 34.9 13.2 21.7 24.1 27.0 34.8 33.4 39.3 27.6 9.3 45.7 109.8 53.5 40.4 22.8 11.3 16.9 15.1 25.3 48.5 27.1 15.5 11.4 52.4 31.7 20.9 58.2 61.6 22.9 43.8 71.3 24.7 20.3 42.4 68.2 37.6 16.1 79.7 34.8 27.1 52.7 0.5 0.2 0.8 0.1 11.8 20.4 0.9 3.1 9.7 0.2 1.1 0.3 20.4 15.9 11.4 4.9 1.3 13.4 0.1 5.8 0.2 2.6 1.9 0.5 2.3 2.2 4.0 1.1 0.7 20.0 8.3 0.2 0.1 18.9 6.4 2.3 0.9 19.6 1.5 1.3 0.1 2.5 0.9 1.8 0.4 1.2 0.8 11.9 5.1 24.1 1.2 2.6 1.0 26.1 1.2 10.7 2.1 2.3 20.0 0.0 4.5 0.2 0.0 8.9 4.1 34.7 0.5 2.8 0.4 46.0 18.4 16.5 79.7 22.8 95.5 38.2 207.1 113.7 5.9 79.3 499.2 318.3 7.6 59.2 34.2 2.6 257.0 214.7 35.4 42.5 38.3 40.2 33.4 39.3 53.5 40.4 48.5 43.8 42.4 52.7 26.1 44.8 12.3 17.6 63.7 10.3 19.0 44.6 5.7 29.9 15.5 11.3 11.3 10.0 36.9 31.3 10.4 30.7 89.8 8.3 1.9 50.2 1.6 10.6 10.3 20.9 8.4 12.0 6.5 10.5 3.7 23.8 10.7 24.4 30.4 10.1 32.9 2.0 45.1 6.7 8.6 13.1 32.6 42.5 11.4 3.8 24.5 40.3 12.4 9.4 19.2 82.0 74.2 9.5 25.1 51.7 8.6 30.9 33.1 23.4 19.8 7.9 25.1 9.2 6.6 10.2 14.6 16.5 32.3 4.9 11.5 12.3 143.6 27.4 10.1 60.0 PIMREG "CATS, FAM64A, FLJ10156, FLJ10491, RCS1" ENSG00000129195 "PICALM interacting mitotic regulator" Q9BSJ6 17 6444441-6451469 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 13.9" "Group enriched" "Detected in some" 6 "Fibroblasts: 5.5;Granulosa cells: 21.5;Hofbauer cells: 7.2;Smooth muscle cells: 14.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.1" "Immune cell enhanced" "Detected in single" "NK-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 161.8" "Region enhanced" "Detected in many" "white matter: 5.7" "Low region specificity" "Detected in single" "HPA043783, HPA049934" Uncertain Enhanced Nucleoplasm Yes Yes "Cluster 22: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA043783: AB_2678669, HPA049934: AB_2680959" "unprognostic (5.32e-3)" "unprognostic (1.14e-2)" "unprognostic (2.33e-1)" "unprognostic (4.37e-3)" "unprognostic (1.46e-1)" "unprognostic (1.24e-2)" "unprognostic (6.55e-3)" "unprognostic (1.23e-3)" "unprognostic (1.80e-1)" "unprognostic (5.88e-2)" "unprognostic (1.47e-3)" "unprognostic (1.50e-2)" "unprognostic (0.00e+0)" "unprognostic (8.65e-2)" "unprognostic (1.04e-1)" "unprognostic (1.01e-1)" "unprognostic (1.11e-1)" 0.5 2.5 0.3 1.3 0.0 2.5 0.8 1.1 0.4 0.9 0.0 3.3 3.0 0.8 0.0 3.3 0.3 0.7 0.3 0.1 0.1 0.3 0.3 0.7 1.5 0.2 0.0 0.8 0.2 0.1 0.1 0.6 0.0 0.3 4.1 0.4 0.7 0.1 0.0 2.7 3.1 2.0 0.0 6.0 1.2 0.3 0.1 13.9 0.4 0.0 2.1 1.3 1.3 0.2 42.1 54.1 161.8 73.1 1.5 4.5 12.6 47.9 29.8 78.6 52.5 32.8 17.9 0.0 18.8 39.8 39.9 29.9 82.6 21.6 41.9 64.6 33.9 0.1 33.8 41.2 0.2 1.7 48.9 2.4 1.5 32.2 12.4 8.0 24.8 36.8 10.1 23.0 49.9 30.5 9.2 0.5 70.9 34.0 37.8 74.9 64.8 29.6 12.9 6.4 36.5 51.3 41.7 42.5 39.1 20.4 19.9 4.0 11.9 59.9 48.4 36.0 80.7 8.2 31.5 0.2 23.6 20.4 94.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.1 0.0 0.1 0.2 1.0 0.1 0.0 0.3 0.3 0.3 0.0 1.1 0.4 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 1.8 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.2 0.0 0.4 1.2 0.6 0.0 0.0 0.0 0.0 0.6 5.5 0.0 0.7 1.3 21.5 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 14.5 0.0 0.0 0.0 0.0 0.1 0.8 1.1 0.0 0.0 PKMYT1 "MYT1, PPP1R126" ENSG00000127564 "Protein kinase, membrane associated tyrosine/threonine 1" Q99640 16 2968024-2980479 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.6;testis: 56.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 29.0;Extravillous trophoblasts: 52.0;Plasma cells: 22.9;Spermatocytes: 114.7;Spermatogonia: 46.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 6 "T-reg: 1.3" "Lineage enriched" "Detected in single" 6 "T-cells: 1.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA068860 Supported "Nucleoplasm,Nucleoli,Golgi apparatus" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 23: Testis - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA068860: AB_2686050" "unprognostic (7.82e-2)" "unprognostic (8.70e-2)" "unprognostic (5.93e-2)" "unprognostic (2.04e-2)" "unprognostic (4.54e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (8.33e-4)" "prognostic unfavorable (3.37e-4)" "unprognostic (4.52e-2)" "unprognostic (2.15e-1)" "unprognostic (1.61e-2)" "unprognostic (7.95e-3)" "unprognostic (0.00e+0)" "unprognostic (1.09e-3)" "unprognostic (9.13e-2)" "unprognostic (1.96e-1)" "unprognostic (5.91e-2)" 1.1 1.0 0.4 6.8 0.5 27.6 0.6 1.6 1.4 2.2 0.2 3.9 2.8 0.6 0.3 11.5 0.4 0.6 0.9 0.5 0.2 0.9 1.6 2.0 8.0 0.7 0.6 0.3 1.8 0.1 1.0 3.1 0.8 1.0 1.3 17.4 1.9 0.1 2.4 4.4 4.0 1.0 0.5 5.6 3.3 56.9 0.7 9.6 0.5 0.0 4.5 0.7 3.3 0.8 84.2 57.0 22.0 31.2 0.3 0.9 64.0 65.5 15.1 40.0 38.4 45.0 49.3 54.2 29.2 7.9 24.2 106.7 15.7 20.7 7.2 71.7 56.7 27.9 52.7 40.0 0.0 31.2 73.6 0.7 1.8 24.0 6.5 5.0 8.4 57.6 80.6 87.0 13.5 127.5 83.6 88.0 37.9 39.3 34.4 93.7 51.2 100.7 7.8 17.7 42.6 46.7 31.9 77.7 23.9 12.1 44.7 56.9 7.7 53.2 69.7 77.3 68.0 67.6 54.2 94.0 19.4 40.0 61.2 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.3 0.3 0.4 0.5 1.6 1.4 0.5 0.2 0.7 0.6 0.8 0.5 0.7 0.8 0.0 0.0 1.1 0.0 1.9 2.5 1.3 2.1 0.6 0.4 1.5 1.3 0.6 1.5 1.6 1.8 6.2 16.0 1.3 5.0 0.0 0.8 20.0 0.6 0.8 0.8 1.8 29.0 0.4 0.6 52.0 2.5 3.1 1.9 0.0 4.5 0.0 0.4 11.8 0.0 0.2 3.6 6.1 2.1 1.8 8.6 0.3 1.9 0.0 0.0 0.7 0.2 0.0 0.0 0.3 0.6 0.3 0.4 22.9 0.7 0.3 0.1 0.2 7.1 0.0 0.1 2.6 114.7 46.1 11.2 0.6 7.4 4.2 0.5 8.6 2.0 PLCXD1 FLJ11323 ENSG00000182378 "Phosphatidylinositol specific phospholipase C X domain containing 1" Q9NUJ7 X 276322-303356 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 34.7;Distal enterocytes: 34.2;Gastric mucus-secreting cells: 33.1;Paneth cells: 40.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 110.4;HEL: 172.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA007721 Approved Approved Cytosol NA Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 36: HEL - Hemostasis" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA007721: AB_1079630" "unprognostic (2.73e-2)" "unprognostic (5.67e-2)" "unprognostic (4.57e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (3.80e-2)" "prognostic favorable (2.50e-4)" "unprognostic (1.47e-3)" "unprognostic (7.92e-2)" "unprognostic (1.72e-2)" "unprognostic (4.80e-2)" "unprognostic (7.25e-2)" "unprognostic (1.11e-3)" "prognostic unfavorable (7.82e-14)" "unprognostic (6.01e-2)" "unprognostic (1.95e-1)" "unprognostic (3.59e-2)" "unprognostic (1.78e-1)" 14.7 4.1 4.6 9.4 8.8 32.9 9.7 13.0 19.2 10.0 0.0 8.2 8.6 5.6 1.4 17.5 9.1 8.8 5.6 4.4 0.0 5.7 10.1 7.4 17.3 3.4 1.5 12.8 7.5 3.2 7.7 7.8 4.4 7.5 5.7 6.0 11.4 3.7 8.4 18.7 12.5 2.7 0.5 17.5 26.9 6.7 4.0 8.9 10.4 2.7 9.0 6.1 9.7 13.4 28.4 110.4 25.7 38.8 5.0 3.9 20.4 24.4 2.9 12.8 12.4 40.6 29.1 34.8 17.9 10.7 19.0 8.5 6.3 15.9 6.7 21.2 46.2 172.6 36.1 59.7 15.6 17.4 63.1 20.1 1.9 47.0 4.9 8.6 9.7 57.2 44.0 18.7 9.2 8.2 52.3 24.2 57.8 7.1 19.2 29.1 13.3 53.9 3.9 12.9 25.9 15.0 24.6 14.4 21.1 17.5 27.6 22.0 7.2 17.1 28.2 18.5 26.9 6.3 17.9 86.4 11.0 44.4 18.2 3.7 2.7 5.4 1.9 6.0 2.7 1.6 1.4 2.4 2.0 5.6 1.8 1.9 3.3 1.2 9.0 2.1 3.2 2.3 4.6 8.8 13.0 19.2 4.4 0.0 3.4 1.5 4.4 0.5 4.0 13.4 15.8 9.6 34.7 5.5 4.1 6.9 13.6 3.9 2.2 7.4 4.7 3.6 6.5 10.0 2.8 0.0 2.1 10.1 4.9 34.2 0.0 6.3 0.9 1.6 3.4 6.1 3.0 9.9 5.3 1.8 11.3 6.1 33.1 3.2 3.8 32.1 4.6 6.9 5.5 8.4 6.1 11.2 0.0 7.3 9.8 0.9 2.5 11.9 0.0 5.6 3.7 2.3 9.2 0.5 5.7 18.8 40.9 3.8 2.7 5.3 3.0 1.7 1.3 7.1 13.1 6.5 7.9 8.4 15.9 4.2 8.7 27.0 3.8 2.8 9.4 8.0 PLIN3 "M6PRBP1, PP17, TIP47" ENSG00000105355 "Perilipin 3" O60664 19 4838341-4867694 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 268.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006427, HPA066538" Uncertain Supported "Lipid droplets" NA Yes 11000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Lipid droplets" "HPA006427: AB_1079289, HPA066538: AB_2685687" "unprognostic (1.18e-1)" "unprognostic (4.86e-2)" "unprognostic (1.55e-2)" "prognostic favorable (2.62e-4)" "unprognostic (2.94e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (3.27e-5)" "prognostic unfavorable (7.67e-6)" "unprognostic (2.27e-1)" "unprognostic (1.28e-1)" "unprognostic (4.34e-2)" "unprognostic (8.24e-2)" "prognostic unfavorable (9.15e-7)" "unprognostic (2.62e-1)" "unprognostic (2.14e-1)" "unprognostic (1.95e-1)" "unprognostic (2.39e-2)" 30.8 69.9 23.3 41.4 39.6 70.8 29.5 44.2 27.5 50.4 25.9 37.6 70.8 22.6 14.4 124.7 22.9 34.5 25.3 22.1 28.6 38.0 26.5 25.7 29.1 51.1 36.1 40.0 20.3 9.8 9.3 33.3 48.9 28.0 20.9 1.7 45.9 21.0 112.0 87.5 73.9 23.9 36.2 32.3 28.5 34.3 39.1 28.0 24.8 36.4 33.0 37.5 55.4 66.0 138.2 79.1 53.6 50.5 59.8 189.8 24.1 196.8 178.9 152.0 142.9 52.6 124.9 72.5 43.3 242.2 82.1 61.3 25.1 108.2 88.2 82.7 35.4 79.1 43.0 97.8 41.4 56.7 112.9 147.1 46.2 107.4 23.6 90.5 81.2 23.5 122.4 31.3 192.1 57.1 78.3 72.9 42.5 63.3 127.7 136.2 74.9 40.2 133.8 31.7 2.3 26.3 62.5 55.5 49.5 43.2 70.4 125.9 125.1 83.3 80.5 333.8 102.9 44.1 58.9 50.8 250.7 79.6 97.3 128.3 141.7 64.8 13.8 100.4 14.6 46.3 24.7 15.9 109.1 36.3 19.4 12.4 173.9 39.5 76.7 82.8 34.1 86.4 23.3 39.6 44.2 27.5 22.1 28.6 51.1 36.1 48.9 36.2 39.1 66.0 19.2 19.2 25.6 5.5 28.5 142.2 62.9 58.8 90.0 0.4 108.0 43.1 2.3 14.3 51.3 11.0 2.1 152.2 34.4 169.7 37.2 114.7 9.7 65.2 50.9 27.7 40.7 18.5 0.8 86.8 77.3 62.9 33.1 78.4 55.8 112.9 26.0 18.2 101.2 0.0 1.1 67.0 28.5 57.8 103.4 14.0 35.8 74.7 55.2 2.8 62.3 23.9 15.5 5.0 17.1 243.4 223.0 53.0 37.1 39.3 268.8 38.8 65.2 0.7 52.6 37.8 66.2 75.1 14.6 109.0 229.3 194.8 20.3 193.4 54.8 69.2 PLPP3 "LPP3, PAP-2b, PPAP2B" ENSG00000162407 "Phospholipid phosphatase 3" O14495 1 56494761-56645301 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 392.7;Hepatic stellate cells: 779.6;Leydig cells: 1092.6;Peritubular cells: 398.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 168.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 2.4;naive B-cell: 2.3" "Lineage enriched" "Detected in single" 6 "B-cells: 2.4" "Cell line enhanced" "Detected in many" "ASC diff: 710.0;ASC TERT1: 351.8;HSkMC: 438.1;U-2197: 660.4" "Low region specificity" "Detected in all" HPA072751 Approved Supported "Golgi apparatus" NA Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA072751: AB_2686555" "unprognostic (2.50e-2)" "unprognostic (3.94e-1)" "unprognostic (1.81e-1)" "unprognostic (1.65e-1)" "unprognostic (2.71e-1)" "unprognostic (2.22e-3)" "unprognostic (5.86e-3)" "unprognostic (7.25e-2)" "unprognostic (1.59e-1)" "unprognostic (3.75e-2)" "unprognostic (3.91e-2)" "unprognostic (3.08e-1)" "prognostic favorable (4.59e-4)" "unprognostic (3.16e-2)" "unprognostic (1.74e-1)" "unprognostic (3.54e-2)" "unprognostic (2.09e-1)" 168.4 53.0 93.9 33.6 94.2 13.1 139.8 87.3 105.9 294.6 50.7 56.7 24.0 107.2 56.2 51.3 122.5 66.3 84.6 88.3 90.6 91.4 182.0 87.0 22.4 107.5 108.1 81.9 36.8 130.2 23.1 225.5 87.7 102.8 41.8 19.0 76.2 169.7 50.9 82.1 45.8 65.6 86.8 23.3 66.0 37.3 113.2 29.8 327.6 63.0 19.9 139.2 142.8 88.6 3.3 10.8 14.1 1.5 710.0 351.8 34.5 39.3 39.7 35.5 17.4 31.8 6.2 5.2 4.6 59.3 39.4 5.9 2.1 0.8 7.4 0.0 9.4 1.3 4.4 44.5 17.3 0.1 0.0 438.1 3.0 34.2 28.6 25.1 34.1 0.4 2.9 0.1 39.0 3.2 0.1 0.5 43.3 9.2 42.6 0.1 0.1 1.7 6.1 32.6 0.4 28.1 12.4 16.1 4.2 42.6 5.2 0.0 21.6 176.2 14.4 660.4 1.8 0.0 0.0 0.0 31.0 1.7 12.7 0.0 0.1 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 2.3 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.1 93.9 94.2 87.3 105.9 88.3 90.6 107.5 108.1 87.7 86.8 113.2 88.6 148.5 25.6 18.9 0.0 7.2 0.0 19.8 0.0 35.3 3.9 12.2 31.2 0.0 44.3 13.0 22.0 0.0 127.0 1.1 8.1 21.5 21.5 7.9 13.9 139.4 148.3 2.4 8.0 0.0 9.2 9.8 392.7 5.6 16.3 3.8 8.1 779.6 132.6 38.8 0.0 0.0 8.5 0.0 35.2 0.0 28.3 1092.6 14.9 0.0 0.0 0.9 136.0 0.0 0.0 0.0 7.9 5.9 398.7 7.1 20.8 15.5 21.3 4.4 4.1 138.1 179.7 107.2 4.5 3.4 16.4 0.0 214.9 5.0 22.4 7.2 20.1 PLSCR1 MMTRA1B ENSG00000188313 "Phospholipid scramblase 1" O15162 3 146515180-146544856 "Predicted intracellular proteins, Transporters" "Antiviral defense, Host-virus interaction" "DNA-binding, Host cell receptor for virus entry, Hydrolase, Nuclease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 291.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 319.8;BJ hTERT+ SV40 Large T+ RasG12V: 418.6;HHSteC: 292.9;SK-MEL-30: 569.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068923, CAB070421" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Plasma membrane" "Golgi apparatus" "CAB070421: AB_11153452, HPA068923: AB_2686059" "unprognostic (7.88e-2)" "unprognostic (1.10e-1)" "unprognostic (5.34e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.12e-1)" "unprognostic (3.35e-1)" "unprognostic (5.22e-2)" "unprognostic (7.73e-3)" "unprognostic (9.19e-3)" "unprognostic (6.93e-3)" "unprognostic (3.07e-3)" "unprognostic (1.10e-1)" "unprognostic (1.09e-3)" "unprognostic (5.26e-2)" "unprognostic (1.64e-2)" "unprognostic (1.76e-1)" "unprognostic (1.63e-1)" 60.6 23.0 11.4 86.7 12.5 64.4 45.9 12.7 17.6 25.9 11.9 65.0 39.8 28.2 31.0 47.9 40.0 66.1 24.3 12.1 13.5 71.9 49.2 49.3 40.6 17.4 14.2 34.9 38.3 16.8 15.4 56.3 15.3 23.7 59.5 9.8 49.1 49.6 10.8 13.6 45.4 41.9 16.2 64.5 44.0 17.1 14.7 30.0 27.8 17.6 39.4 68.1 29.5 14.0 106.2 41.5 26.4 12.1 40.9 65.0 40.5 32.6 88.4 319.8 418.6 34.0 88.1 8.4 75.6 20.6 245.9 86.2 21.2 32.7 56.6 32.9 21.6 66.1 12.5 25.2 292.9 40.3 35.4 106.3 53.3 36.6 182.3 52.6 49.4 19.1 44.7 104.0 66.9 41.0 30.6 16.1 25.8 71.6 37.6 27.4 28.1 2.9 95.9 29.6 16.3 0.0 42.6 20.9 569.9 35.8 20.7 46.8 30.6 26.9 22.7 59.1 55.8 79.2 15.6 0.4 27.0 29.0 23.3 41.1 157.6 44.3 20.8 159.6 30.0 25.2 13.5 18.5 105.8 19.7 9.3 13.9 100.0 57.8 94.8 28.5 8.3 79.3 11.4 12.5 12.7 17.6 12.1 13.5 17.4 14.2 15.3 16.2 14.7 14.0 191.4 35.3 43.0 12.7 28.2 37.0 106.5 92.1 26.2 0.7 36.0 22.6 7.3 124.4 110.4 95.6 0.0 53.7 25.4 134.2 74.3 291.6 2.0 56.1 24.5 135.2 33.1 18.3 7.1 217.4 114.1 74.8 47.9 58.2 28.4 60.5 100.6 29.7 139.9 0.0 9.0 71.5 79.3 86.2 162.9 6.8 114.9 185.5 48.0 35.6 72.3 64.3 32.0 7.1 0.3 157.6 110.3 45.9 18.2 79.6 40.7 75.0 133.5 1.6 39.5 63.4 59.2 1.5 2.4 21.8 28.6 44.5 25.9 42.6 69.4 211.9 PNO1 "KHRBP1, RRP20" ENSG00000115946 "Partner of NOB1 homolog" Q9NRX1 2 68157888-68176238 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056928 Supported Nucleoplasm,Nucleoli NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoli Nucleoplasm "HPA056928: " "unprognostic (1.81e-3)" "unprognostic (4.83e-1)" "unprognostic (5.93e-2)" "prognostic unfavorable (1.12e-4)" "unprognostic (5.88e-2)" "unprognostic (1.66e-3)" "prognostic unfavorable (3.04e-8)" "unprognostic (5.82e-2)" "unprognostic (2.59e-2)" "unprognostic (1.16e-1)" "unprognostic (9.13e-3)" "unprognostic (3.33e-2)" "unprognostic (1.46e-2)" "unprognostic (1.42e-1)" "unprognostic (2.58e-1)" "unprognostic (3.74e-2)" "unprognostic (7.66e-2)" 15.1 14.2 6.4 12.1 8.0 19.5 11.6 7.0 11.8 7.6 6.9 9.7 7.6 9.8 11.2 11.1 8.8 9.9 10.2 12.0 7.3 14.1 12.6 8.6 12.6 6.7 6.9 7.0 12.7 12.5 7.1 12.7 6.8 10.0 9.1 19.0 7.1 10.8 20.1 9.1 6.7 11.5 6.7 8.2 8.8 8.9 6.9 8.1 12.5 12.6 12.2 19.8 7.6 7.4 37.8 40.1 18.5 30.5 22.5 18.3 46.0 34.7 23.0 39.1 27.8 77.9 21.9 51.4 28.5 23.6 54.0 31.6 60.6 41.9 61.3 35.2 40.6 49.7 17.4 58.2 34.6 40.2 22.4 24.1 30.2 39.4 45.0 11.3 29.1 32.7 69.7 27.3 35.7 27.4 39.9 38.1 52.0 68.7 43.1 33.3 45.2 54.8 29.8 31.7 32.7 24.0 26.1 32.4 57.8 29.7 22.9 22.4 21.2 44.2 48.0 40.1 97.9 21.6 33.1 78.1 36.3 59.1 62.1 0.9 12.6 2.8 12.2 18.1 19.1 19.2 13.8 14.4 16.8 14.5 16.0 14.6 2.4 15.0 13.0 11.8 16.0 21.3 6.4 8.0 7.0 11.8 12.0 7.3 6.7 6.9 6.8 6.7 6.9 7.4 23.7 16.0 13.2 3.3 29.9 83.2 62.8 29.5 25.6 22.7 18.6 18.4 11.9 18.6 36.2 7.3 12.5 39.5 20.2 7.9 19.6 36.7 33.5 28.7 37.7 25.5 17.3 21.4 10.6 29.8 43.5 28.3 9.7 20.9 31.6 13.6 12.5 15.8 26.0 18.5 9.0 12.1 30.5 10.4 38.7 7.7 12.5 20.7 12.4 4.7 18.9 21.0 14.4 7.1 10.4 29.1 5.8 16.6 27.8 56.6 4.6 34.7 28.6 51.3 6.6 40.4 29.6 28.9 41.7 21.0 56.1 47.6 25.7 20.5 20.2 37.6 PNRC1 "B4-2, PROL2, PRR2" ENSG00000146278 "Proline rich nuclear receptor coactivator 1" Q12796 6 89080751-89085160 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 1848.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 212.8;hTCEpi: 234.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029839, HPA066513" Approved Approved Nucleoplasm,Nucleoli NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Nucleoli" "HPA029839: AB_10601247, HPA066513: AB_2685684" "unprognostic (9.02e-3)" "unprognostic (7.65e-2)" "unprognostic (3.01e-2)" "unprognostic (2.31e-2)" "unprognostic (6.10e-2)" "unprognostic (1.52e-1)" "unprognostic (2.28e-1)" "unprognostic (1.78e-1)" "unprognostic (5.20e-2)" "unprognostic (5.28e-3)" "unprognostic (1.96e-2)" "unprognostic (6.29e-2)" "prognostic unfavorable (6.88e-6)" "unprognostic (8.63e-3)" "unprognostic (2.05e-1)" "unprognostic (1.03e-1)" "unprognostic (5.09e-2)" 232.7 171.7 61.6 145.9 66.3 368.1 135.4 84.0 67.5 93.8 47.9 158.4 70.2 100.6 80.4 91.4 204.4 139.3 132.5 58.3 74.2 103.5 318.1 159.6 134.1 87.7 65.7 222.5 89.2 86.8 78.5 122.6 73.0 95.0 77.5 129.8 91.9 84.3 460.6 147.5 94.3 130.3 69.5 139.6 104.6 50.1 57.4 165.9 105.6 163.4 111.2 141.4 98.5 80.4 12.1 12.0 25.3 42.4 96.7 166.6 16.9 16.0 110.6 29.5 69.0 10.2 34.5 25.9 71.2 19.4 116.3 40.5 13.3 23.9 45.6 31.8 36.3 4.7 69.8 31.9 212.8 25.0 57.9 117.6 234.4 19.6 90.1 107.9 49.4 30.3 4.1 81.0 33.3 11.5 6.8 124.7 7.0 13.9 23.1 29.1 30.0 21.5 70.2 21.1 15.7 42.2 40.3 56.3 44.0 73.6 27.9 119.4 44.8 23.1 13.2 16.2 5.9 118.3 64.0 9.0 46.3 20.6 14.9 32.8 17.3 103.8 18.3 19.0 19.0 20.7 22.1 19.7 11.3 23.0 24.9 25.9 100.9 19.2 17.9 18.7 19.0 10.5 61.6 66.3 84.0 67.5 58.3 74.2 87.7 65.7 73.0 69.5 57.4 80.4 405.7 141.1 149.8 36.2 747.6 968.9 776.8 98.9 1286.2 130.6 412.5 381.5 188.6 230.2 65.2 90.1 50.1 235.8 662.8 158.1 234.8 203.5 103.4 528.4 655.3 356.1 248.0 284.1 10.0 238.2 78.6 720.1 225.8 955.1 164.6 153.2 238.5 207.6 229.4 72.3 15.5 200.7 34.6 452.6 1848.0 41.5 481.9 898.3 439.4 39.4 763.5 403.3 440.8 20.1 41.5 143.0 184.6 377.3 530.6 738.5 211.1 319.2 61.5 134.8 420.7 731.3 725.6 51.9 64.6 840.2 1250.8 274.5 735.8 214.3 136.9 472.8 POLD3 "KIAA0039, P66, P68, PPP1R128" ENSG00000077514 "DNA polymerase delta 3, accessory subunit" Q15054 11 74493851-74669117 "Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA excision, DNA repair, DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA058846 Enhanced Supported Nucleoplasm NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA058846: AB_2683833" "unprognostic (3.68e-1)" "unprognostic (3.22e-2)" "unprognostic (2.05e-3)" "unprognostic (3.28e-1)" "unprognostic (1.74e-1)" "unprognostic (3.49e-1)" "prognostic unfavorable (9.17e-4)" "unprognostic (1.08e-1)" "prognostic unfavorable (5.48e-4)" "unprognostic (3.99e-3)" "unprognostic (1.54e-3)" "unprognostic (9.21e-3)" "prognostic unfavorable (7.90e-6)" "unprognostic (7.92e-3)" "unprognostic (2.65e-1)" "unprognostic (9.11e-2)" "unprognostic (1.23e-1)" 7.9 6.2 6.1 14.6 6.0 10.1 11.1 6.0 7.3 10.6 7.6 17.2 15.7 16.5 12.0 12.9 16.3 14.9 8.9 5.9 6.1 44.5 7.1 11.5 14.5 4.9 5.6 16.0 11.4 7.8 4.6 11.5 5.6 8.3 17.9 14.9 6.8 10.1 7.7 11.6 14.4 15.3 5.1 11.4 15.4 19.6 5.5 15.7 15.0 12.5 15.2 12.7 7.5 7.4 32.2 28.6 43.6 29.8 13.2 22.5 30.9 42.7 23.9 43.7 37.0 37.8 40.8 45.7 30.9 20.5 25.3 41.2 36.3 28.0 54.6 34.5 23.3 29.1 44.3 12.8 9.5 56.4 25.3 10.0 17.3 51.1 27.3 13.8 17.1 39.8 26.7 35.5 25.6 25.3 63.4 25.3 26.4 95.3 29.1 60.0 109.4 37.9 20.2 30.6 29.0 19.5 50.7 25.3 49.7 26.2 29.5 35.7 16.4 42.9 30.8 48.8 34.2 24.8 56.6 102.4 24.5 35.1 33.2 7.3 22.6 15.9 9.2 18.5 9.1 10.1 11.7 8.2 17.7 8.0 11.6 9.6 19.4 10.8 19.0 5.2 13.7 13.0 6.1 6.0 6.0 7.3 5.9 6.1 4.9 5.6 5.6 5.1 5.5 7.4 14.8 12.8 20.0 13.1 9.7 5.9 7.0 11.4 12.5 12.3 10.5 12.8 7.8 7.2 17.7 9.2 8.4 19.7 11.1 17.9 5.9 17.2 28.3 24.8 17.1 14.2 5.4 24.2 20.1 32.1 26.7 13.1 16.8 14.4 19.0 20.9 8.2 4.9 15.6 23.5 15.3 12.7 12.2 12.9 7.2 23.1 12.5 16.9 3.6 15.0 25.3 15.3 9.2 6.6 18.7 17.4 13.4 8.6 11.4 11.4 10.7 39.1 45.2 19.1 6.6 13.7 12.4 60.3 37.7 11.2 5.4 13.0 11.8 10.0 19.9 10.5 POLQ POLH ENSG00000051341 "DNA polymerase theta" O75417 3 121431427-121546641 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;lymphoid tissue: 4.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 16.4;Excitatory neurons: 9.5;Granulosa cells: 12.6;Inhibitory neurons: 7.8;Plasma cells: 12.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 2.5" HPA053359 Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus, Cytosol" "HPA053359: " "unprognostic (1.59e-1)" "unprognostic (4.18e-2)" "unprognostic (2.66e-2)" "prognostic unfavorable (5.46e-5)" "unprognostic (2.70e-1)" "unprognostic (6.23e-3)" "unprognostic (3.09e-5)" "unprognostic (8.55e-3)" "unprognostic (1.09e-4)" "unprognostic (2.86e-1)" "unprognostic (5.59e-5)" "unprognostic (2.06e-3)" "unprognostic (0.00e+0)" "prognostic favorable (1.04e-4)" "unprognostic (1.76e-1)" "unprognostic (6.01e-2)" "unprognostic (5.76e-2)" 0.1 0.2 0.0 1.6 0.1 6.0 0.4 1.0 0.2 0.2 0.0 1.2 1.2 0.2 0.0 2.0 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.2 2.8 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 2.0 0.0 0.3 0.0 0.0 1.4 0.9 0.4 0.0 0.8 0.5 2.2 0.0 4.5 0.0 0.0 2.3 0.3 0.5 0.0 18.2 12.1 10.2 7.2 0.9 1.2 9.2 8.5 3.2 9.7 12.9 9.8 6.6 21.5 3.7 4.6 11.7 14.0 12.2 5.4 16.4 6.3 6.7 13.8 8.0 6.1 0.1 15.1 12.1 0.2 0.4 8.9 5.4 1.7 4.9 7.9 9.3 15.9 10.3 7.1 13.7 8.8 9.7 5.5 5.9 11.4 12.2 7.6 3.1 10.3 5.5 5.0 9.8 5.2 3.4 8.8 4.8 14.8 3.8 8.6 11.2 3.4 11.1 8.0 6.9 21.8 4.1 11.0 6.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 1.6 0.7 0.9 0.5 0.6 0.0 0.9 0.6 0.6 1.6 0.0 2.0 0.0 0.0 3.1 0.6 1.6 0.0 0.1 0.4 0.9 1.0 0.5 0.0 16.4 9.5 0.0 3.3 1.2 4.6 1.0 0.0 12.6 0.0 0.2 2.3 0.0 7.8 1.6 2.0 1.3 1.2 0.7 0.3 1.7 0.0 1.0 0.6 0.4 0.0 1.5 1.3 0.2 1.2 0.0 12.2 0.5 0.2 0.1 2.4 0.2 0.0 0.1 1.0 6.8 3.4 4.9 0.1 0.3 1.8 0.9 3.2 0.8 POLR2A "POLR2, POLRA, RPB1" ENSG00000181222 "RNA polymerase II subunit A" 17 7484366-7514616 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.4;lymphoid tissue: 1.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SCLC-21H: 3.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012226, CAB016388, HPA021563, HPA053012" Enhanced Nucleoplasm,Cytosol NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "CAB012226: AB_304749, CAB016388: AB_677353, HPA021563: AB_1855526, HPA053012: AB_2682017" "unprognostic (2.03e-1)" "unprognostic (1.32e-1)" "unprognostic (1.58e-1)" "unprognostic (2.40e-1)" "unprognostic (1.71e-1)" "unprognostic (5.43e-2)" "unprognostic (8.77e-3)" "unprognostic (1.48e-1)" "unprognostic (5.19e-3)" "unprognostic (1.81e-1)" "unprognostic (1.52e-1)" "unprognostic (3.70e-2)" "unprognostic (1.01e-3)" "unprognostic (1.25e-1)" "unprognostic (2.30e-2)" "unprognostic (1.49e-1)" "unprognostic (4.70e-2)" 0.1 0.7 0.4 1.6 0.2 0.2 0.1 0.3 1.9 0.0 0.8 0.1 0.5 0.1 0.0 0.0 0.2 0.1 0.1 0.7 0.4 0.1 0.0 0.2 0.2 2.4 0.7 0.1 0.0 0.1 0.2 1.1 0.2 0.2 0.3 0.0 0.0 0.5 0.1 0.4 0.0 0.4 0.2 0.0 0.7 1.1 0.2 0.0 0.1 0.0 0.0 1.6 1.0 1.7 0.5 1.5 0.4 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.6 0.4 0.4 0.0 0.6 1.0 2.1 0.0 0.0 0.3 0.0 0.5 0.0 0.9 0.0 1.6 2.9 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.3 1.0 0.4 2.1 0.0 0.0 2.5 2.3 1.0 0.0 2.7 3.5 2.8 1.2 0.8 0.0 0.0 0.8 1.6 0.0 1.0 0.5 1.1 2.0 0.4 0.2 1.6 1.1 0.8 1.0 0.0 2.2 0.8 2.0 0.9 2.5 1.1 0.3 0.8 2.2 0.5 1.3 1.0 0.0 2.0 4.2 0.0 3.2 10.1 0.4 0.2 0.3 1.9 0.7 0.4 2.4 0.7 1.1 0.4 1.1 1.6 124.2 22.4 41.6 13.4 68.0 42.8 40.7 33.8 64.3 90.4 56.5 187.1 26.9 38.6 30.3 23.9 110.5 35.9 153.5 55.0 3.9 27.0 25.0 74.9 64.4 57.7 76.7 43.3 18.1 30.2 28.7 53.3 103.0 67.3 42.5 46.0 40.4 29.9 45.4 55.5 14.9 43.9 26.4 42.1 38.3 7.4 37.0 65.7 37.4 19.7 38.2 27.3 26.8 17.6 17.8 32.0 35.9 41.8 62.0 27.9 42.5 13.2 38.4 90.5 6.6 94.4 53.9 58.5 120.2 73.8 41.2 53.8 89.2 49.8 32.6 30.8 PPARGC1B "PERC, PGC1B" ENSG00000155846 "PPARG coactivator 1 beta" Q86YN6 5 149730298-149855022 "Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 12.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 111.8;Cone photoreceptor cells: 135.5;Rod photoreceptor cells: 72.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 9.7" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA050543 Supported Nucleoplasm,Cytosol NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 15: RT4 - Unknown function" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm Cytosol "HPA050543: AB_2681165" "unprognostic (2.86e-1)" "unprognostic (1.07e-2)" "unprognostic (5.09e-3)" "unprognostic (1.13e-3)" "unprognostic (2.63e-1)" "unprognostic (2.00e-3)" "unprognostic (4.51e-3)" "unprognostic (6.55e-2)" "unprognostic (9.14e-3)" "unprognostic (2.65e-2)" "unprognostic (1.83e-1)" "unprognostic (1.21e-1)" "unprognostic (9.01e-6)" "unprognostic (8.45e-2)" "unprognostic (5.09e-2)" "unprognostic (1.51e-1)" "unprognostic (2.77e-3)" 2.2 0.9 2.1 2.4 2.2 2.0 1.4 9.7 3.1 1.4 0.0 7.0 7.0 2.1 1.1 4.1 2.2 1.2 6.3 1.6 0.4 0.8 1.6 3.6 1.4 1.9 0.2 1.3 1.0 4.4 0.6 1.5 2.0 1.8 6.0 12.4 1.4 3.3 6.2 3.3 6.4 2.8 0.4 2.1 3.8 0.8 0.3 0.9 0.4 2.5 1.8 3.7 2.6 0.5 0.5 1.9 0.7 4.5 1.8 0.6 7.3 0.3 0.0 0.5 0.7 8.5 1.8 9.2 1.3 0.0 2.1 5.5 6.9 3.5 0.6 0.5 5.9 8.6 3.6 1.8 0.5 12.0 3.2 0.9 4.6 1.8 3.0 0.2 1.0 4.0 6.0 2.9 0.4 2.3 4.4 5.4 2.9 2.6 4.8 8.3 5.0 5.1 1.4 11.2 2.4 0.5 1.2 9.8 1.5 1.3 2.5 3.9 1.3 1.0 1.6 3.6 1.8 3.6 2.8 5.3 2.2 7.4 0.9 0.5 0.9 0.1 0.1 1.7 0.3 0.8 0.1 0.1 1.1 0.3 0.2 0.2 0.6 0.3 3.1 0.1 0.1 0.3 2.1 2.2 9.7 3.1 1.6 0.4 1.9 0.2 2.0 0.4 0.3 0.5 6.1 0.0 1.1 1.6 3.0 5.1 3.9 17.9 12.0 111.8 2.5 3.2 22.3 1.5 7.4 1.8 135.5 1.8 0.7 15.4 1.9 0.5 0.3 1.7 4.1 5.4 5.4 5.7 29.2 0.8 1.6 2.7 18.8 2.5 1.3 2.1 4.2 3.5 7.6 8.4 26.2 10.3 0.0 12.5 4.7 0.2 1.5 12.1 3.6 12.2 6.1 4.0 2.1 12.1 0.9 0.5 6.7 0.4 5.5 5.1 19.6 3.0 2.9 72.0 6.6 3.0 8.9 0.2 3.2 23.1 10.7 4.9 2.0 2.1 24.9 6.1 PRNP "AltPrP, CD230, CJD, GSS, PRIP, PRP" ENSG00000171867 "Prion protein" P04156 20 4686350-4701590 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cell cycle, Growth arrest" Prion "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 412.6;Basal squamous epithelial cells: 369.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "basophil: 875.9" "Lineage enriched" "Detected in all" 9 "granulocytes: 875.9" "Cell line enhanced" "Detected in many" "WM-115: 1039.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042754, HPA043398" Enhanced Approved "Nuclear membrane,Vesicles,Cytosol" NA Yes 5100000 "Cluster 38: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 41: Macrophages - Immune response" "Nuclear membrane, Cytosol" Vesicles "HPA042754: AB_10964203, HPA043398: AB_2678461" "unprognostic (1.50e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (2.96e-4)" "prognostic unfavorable (4.64e-4)" "prognostic unfavorable (2.52e-4)" "unprognostic (1.94e-2)" "prognostic unfavorable (7.41e-5)" "unprognostic (7.60e-3)" "unprognostic (2.50e-1)" "unprognostic (7.12e-2)" "unprognostic (3.44e-1)" "unprognostic (1.04e-1)" "unprognostic (6.75e-2)" "unprognostic (7.28e-3)" "unprognostic (3.37e-1)" "unprognostic (2.04e-1)" "unprognostic (1.69e-2)" 87.0 92.4 283.8 52.4 308.4 83.7 106.7 255.1 385.9 135.4 415.8 184.2 37.1 125.5 59.1 79.2 79.9 110.1 197.5 315.6 244.8 132.8 79.7 79.2 59.8 262.8 260.8 163.7 41.5 62.8 83.8 66.9 270.1 146.1 70.5 178.6 60.3 148.2 64.0 95.4 47.4 140.8 265.0 75.2 61.6 68.1 302.5 47.9 89.1 74.0 60.0 124.9 83.4 292.8 226.4 141.6 41.7 64.2 329.6 199.9 36.6 363.4 527.6 175.5 177.7 50.0 171.5 40.9 79.2 727.9 391.8 508.8 45.9 498.3 326.2 31.8 39.0 0.2 19.6 193.8 402.0 72.8 16.5 177.5 711.9 701.8 583.9 257.0 152.8 28.6 22.8 142.9 205.1 45.7 28.8 46.2 33.1 99.8 266.4 33.9 110.0 38.3 88.7 40.3 49.2 7.0 98.9 144.3 554.1 56.4 30.2 38.8 224.5 282.9 127.1 158.6 296.1 63.1 129.5 132.9 226.8 51.9 1039.0 875.9 74.1 5.4 67.3 60.9 100.7 25.1 56.9 55.8 62.9 25.6 33.5 40.1 4.6 23.6 50.4 24.6 72.8 72.7 283.8 308.4 255.1 385.9 315.6 244.8 262.8 260.8 270.1 265.0 302.5 292.8 44.9 80.1 45.4 120.2 85.3 412.6 211.8 132.5 369.3 265.4 60.8 103.0 257.7 32.9 68.2 33.1 116.7 7.7 71.8 2.6 11.7 58.1 6.0 14.1 73.2 66.7 29.9 31.8 125.5 14.7 6.3 177.4 14.8 18.2 173.0 25.5 41.0 36.2 63.6 45.4 170.8 5.4 40.7 219.1 200.4 13.6 143.2 126.3 168.9 59.0 54.5 142.4 42.2 95.0 158.8 18.7 4.5 170.0 47.0 120.3 2.2 84.0 38.1 99.0 13.1 73.0 82.3 36.6 4.5 81.6 284.4 14.4 107.2 10.3 8.8 122.6 PRR11 FLJ11029 ENSG00000068489 "Proline rich 11" Q96HE9 17 59155732-59206709 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.1;lymphoid tissue: 20.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 26.3;Extravillous trophoblasts: 22.3;Granulosa cells: 14.4;Kupffer cells: 18.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 9.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA023923, HPA052376" Uncertain Approved "Endoplasmic reticulum" Yes Yes "Cluster 14: Monocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Endoplasmic reticulum" "HPA023923: AB_1855783, HPA052376: AB_2681803" "unprognostic (1.74e-2)" "unprognostic (1.02e-1)" "unprognostic (1.30e-2)" "prognostic unfavorable (1.90e-4)" "unprognostic (2.15e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.35e-7)" "prognostic unfavorable (1.79e-4)" "unprognostic (7.22e-3)" "unprognostic (2.00e-2)" "prognostic unfavorable (6.18e-4)" "unprognostic (2.80e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.56e-2)" "unprognostic (5.21e-2)" "unprognostic (1.84e-1)" "unprognostic (1.55e-3)" 1.3 0.7 1.8 6.5 2.0 18.1 1.8 4.3 2.7 1.2 1.1 4.6 6.5 1.7 0.5 3.8 1.4 1.4 1.0 2.0 1.3 0.6 1.4 2.3 10.3 2.3 1.5 1.4 0.5 0.3 0.0 4.3 2.2 0.8 5.6 1.7 0.6 0.7 1.2 3.1 5.0 3.6 1.1 3.3 2.4 1.8 2.3 20.6 1.3 0.4 12.0 2.0 0.6 3.7 105.3 56.9 84.5 24.8 2.4 16.0 31.7 66.7 41.9 69.1 54.2 68.4 78.7 80.2 65.9 52.7 56.2 40.7 67.0 73.9 145.0 99.3 39.1 86.4 58.8 50.3 0.6 88.7 32.5 4.0 5.3 81.9 109.0 17.1 77.2 57.9 48.6 76.7 72.8 95.2 80.7 26.1 31.9 52.0 82.5 67.3 135.7 45.9 20.0 32.4 34.5 45.4 61.7 18.4 29.2 38.0 54.4 34.1 57.8 146.4 157.3 73.5 117.8 48.8 108.2 73.6 34.5 47.4 150.1 1.7 2.1 2.3 0.6 4.0 0.2 1.1 0.5 0.7 2.6 0.6 0.3 0.5 2.1 0.5 9.5 1.1 1.4 0.8 1.8 2.0 4.3 2.7 2.0 1.3 2.3 1.5 2.2 1.1 2.3 3.7 4.5 0.0 1.7 3.3 3.1 1.9 2.0 1.5 0.0 2.0 0.8 1.5 2.0 1.5 1.6 0.0 0.0 6.2 1.4 2.0 0.0 0.4 0.9 1.4 1.9 3.6 4.9 26.3 1.6 0.5 22.3 2.9 2.6 2.2 2.5 14.4 4.2 0.3 7.8 1.7 1.8 5.0 0.0 18.6 6.3 0.4 0.9 7.8 1.8 2.8 8.4 0.9 4.1 2.0 3.4 0.9 0.7 2.2 9.7 1.1 0.5 0.5 0.6 3.2 0.0 2.9 3.3 2.6 5.1 5.5 1.3 2.1 3.3 1.3 8.4 1.7 PRR13 "DKFZP564J157, FLJ23818" ENSG00000205352 "Proline rich 13" Q9NZ81 12 53441678-53446645 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 884.9;Distal tubular cells: 1365.6;Paneth cells: 858.1;Proximal enterocytes: 1642.7;Proximal tubular cells: 1097.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039396, HPA046219" Uncertain Supported Nucleoplasm NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "HPA039396: AB_2676484, HPA046219: AB_10963936" "unprognostic (1.09e-1)" "prognostic favorable (9.08e-4)" "unprognostic (1.15e-1)" "unprognostic (3.26e-1)" "unprognostic (8.97e-3)" "unprognostic (4.88e-3)" "unprognostic (1.86e-3)" "unprognostic (7.23e-2)" "unprognostic (1.23e-1)" "unprognostic (3.49e-1)" "unprognostic (1.41e-2)" "unprognostic (5.41e-2)" "unprognostic (6.81e-3)" "unprognostic (1.81e-1)" "unprognostic (1.08e-1)" "unprognostic (2.34e-1)" "prognostic favorable (7.55e-4)" 143.8 207.8 110.8 159.2 110.1 279.1 139.2 112.6 147.7 118.9 109.7 316.1 451.6 104.6 110.8 143.4 139.2 147.1 110.6 105.8 147.8 457.9 192.8 164.3 185.3 126.6 132.1 118.8 133.3 76.0 114.6 95.2 126.3 139.6 265.7 44.0 115.5 86.6 131.6 108.7 432.6 91.4 114.3 230.2 247.8 46.4 118.4 139.0 131.8 59.6 190.4 143.7 111.7 117.1 171.7 339.6 82.6 89.4 135.3 185.3 178.4 142.5 213.0 185.6 179.4 623.1 373.6 265.1 453.5 206.8 225.4 146.6 167.8 225.0 217.9 263.1 124.6 382.4 166.4 294.6 340.7 573.2 489.5 232.6 221.2 326.5 223.6 192.6 195.3 166.1 340.1 254.6 285.1 472.5 325.8 563.8 127.5 229.2 230.7 287.6 67.8 273.9 406.2 283.8 72.3 56.5 202.5 276.7 237.2 169.5 394.0 436.2 196.3 117.2 114.0 201.3 138.0 190.7 241.6 386.4 153.3 345.1 220.2 851.3 824.0 1620.1 511.1 941.9 503.0 888.2 563.7 545.8 649.3 855.6 520.6 557.7 2095.7 584.5 1014.6 539.0 824.8 1573.1 110.8 110.1 112.6 147.7 105.8 147.8 126.6 132.1 126.3 114.3 118.4 117.1 66.8 83.3 110.4 6.8 219.1 47.5 147.8 204.8 82.6 11.1 114.3 95.2 26.4 198.8 145.1 187.6 29.2 225.3 159.1 884.9 1365.6 228.0 12.6 182.7 67.1 80.3 169.8 99.2 6.3 253.9 337.7 76.6 263.0 127.4 186.7 53.4 78.1 152.8 355.2 18.5 7.1 346.9 193.3 345.0 174.4 8.7 58.1 266.8 108.5 9.4 384.7 85.3 297.6 4.5 12.9 332.3 858.1 45.9 120.9 174.7 1642.7 1097.6 215.9 20.9 78.9 33.6 67.1 29.7 22.8 107.1 56.0 291.0 212.7 88.4 340.0 193.1 PSMC3IP "GT198, Hop2, HUMGT198A, TBPIP" ENSG00000131470 "PSMC3 interacting protein" Q9P2W1 17 42572310-42577831 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA recombination, Meiosis" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 23.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 113.3;Spermatogonia: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA044439 Enhanced Supported Nucleoplasm NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA044439: AB_10964210" "unprognostic (2.98e-1)" "unprognostic (3.66e-1)" "unprognostic (1.33e-1)" "unprognostic (2.87e-1)" "unprognostic (6.59e-2)" "unprognostic (2.39e-2)" "unprognostic (1.28e-7)" "unprognostic (6.22e-2)" "unprognostic (6.14e-2)" "unprognostic (2.47e-1)" "unprognostic (7.26e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (9.41e-4)" "unprognostic (6.03e-2)" "unprognostic (3.68e-1)" "unprognostic (1.39e-2)" "unprognostic (1.82e-1)" 3.3 1.4 8.3 2.5 8.9 8.2 3.8 8.7 10.3 3.5 7.9 4.2 1.3 3.7 3.8 3.0 6.2 1.4 1.8 7.8 8.5 2.8 0.8 2.3 3.9 9.4 8.9 3.4 2.1 7.6 1.5 4.2 9.2 3.6 3.0 7.3 1.5 3.9 1.5 3.1 1.6 5.2 9.0 1.9 2.4 23.7 8.8 7.4 1.8 2.3 5.5 2.9 2.9 8.9 21.1 29.0 48.3 34.9 11.0 15.0 11.0 80.4 23.7 63.4 78.3 28.6 12.9 21.1 17.6 22.2 27.6 29.9 36.9 28.8 73.0 31.0 30.0 13.5 66.1 35.0 1.6 46.3 14.4 5.3 6.4 101.5 34.2 9.4 18.8 28.3 44.5 38.2 56.6 21.8 33.3 28.0 30.0 23.9 26.8 32.3 50.7 20.6 14.8 16.6 65.1 40.6 32.1 11.8 34.7 24.3 28.3 20.3 8.8 70.5 41.1 55.2 128.6 30.0 54.1 30.8 32.8 21.2 79.7 0.0 0.0 0.9 0.7 0.2 0.9 1.1 0.4 0.7 0.0 0.3 0.1 0.4 0.9 0.1 0.3 2.8 0.7 0.1 8.3 8.9 8.7 10.3 7.8 8.5 9.4 8.9 9.2 9.0 8.8 8.9 6.0 3.2 3.7 2.3 6.4 5.4 2.7 3.7 0.0 5.9 4.8 5.2 0.9 4.3 2.8 3.7 10.4 15.6 3.7 1.4 0.0 4.5 12.8 11.1 5.8 4.4 0.0 19.8 1.1 3.3 19.1 5.5 1.5 5.0 1.3 7.7 2.9 2.2 7.4 0.0 1.2 1.2 4.1 3.0 2.6 13.1 5.3 2.4 5.4 2.8 5.8 4.6 3.1 1.0 1.5 2.0 0.3 8.6 6.5 2.0 0.2 2.2 14.9 13.9 19.7 8.6 16.0 113.3 44.6 3.2 4.1 5.2 2.7 2.5 2.5 1.7 PTMS ParaT ENSG00000159335 Parathymosin P20962 12 6765516-6770952 "Predicted intracellular proteins" Immunity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 565.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 25.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 25.6" "Cell line enhanced" "Detected in all" "HDLM-2: 672.8" HPA038186 Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim" No Yes 300000 "Cluster 41: Basophils - Cellular respiration" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA038186: AB_10673042" "unprognostic (3.11e-2)" "unprognostic (1.31e-3)" "unprognostic (1.76e-1)" "unprognostic (3.57e-2)" "unprognostic (1.09e-1)" "unprognostic (2.83e-1)" "unprognostic (1.13e-1)" "unprognostic (2.47e-1)" "unprognostic (4.16e-1)" "unprognostic (1.01e-1)" "unprognostic (8.69e-3)" "unprognostic (2.52e-1)" "prognostic unfavorable (6.18e-5)" "unprognostic (1.02e-1)" "unprognostic (3.21e-1)" "unprognostic (2.35e-3)" "unprognostic (1.55e-2)" 138.4 78.4 115.9 37.0 105.9 14.3 121.4 103.2 122.3 188.2 48.6 293.9 33.0 243.9 29.0 128.0 145.3 28.9 98.7 117.0 74.3 186.6 565.2 173.5 22.7 45.9 43.5 239.9 50.3 82.4 96.3 49.4 48.0 194.3 28.9 64.6 94.4 86.8 56.3 116.8 101.1 98.8 31.6 61.4 109.5 32.6 86.0 16.3 109.5 16.2 20.1 176.6 137.5 72.5 49.2 250.8 324.8 320.3 149.8 126.2 127.5 210.9 189.2 157.6 130.1 153.8 190.2 19.5 151.8 321.7 143.2 104.6 178.7 159.3 61.9 672.8 219.1 27.5 160.6 58.1 174.1 7.7 56.6 123.7 68.8 121.4 245.6 237.7 175.3 8.6 175.5 50.6 139.8 144.1 9.2 40.7 347.6 92.2 180.8 4.2 99.8 39.6 124.7 12.5 107.4 363.6 254.7 86.9 186.1 230.0 75.9 23.4 296.7 239.6 344.2 36.6 195.2 42.4 19.3 25.4 196.5 18.1 183.6 25.6 0.4 3.6 1.3 0.1 0.6 0.1 0.1 1.1 0.3 0.0 0.0 0.1 1.3 0.1 0.0 4.4 0.5 0.4 115.9 105.9 103.2 122.3 117.0 74.3 45.9 43.5 48.0 31.6 86.0 72.5 370.5 0.0 14.1 9.4 22.8 289.5 328.0 44.6 257.8 325.5 239.2 275.5 10.4 88.6 16.7 154.5 200.1 153.6 88.4 99.8 234.8 61.9 6.6 73.1 494.8 342.7 513.3 248.6 28.7 34.0 404.0 292.4 66.3 117.5 52.8 216.3 325.2 710.0 491.3 116.1 15.2 229.4 22.4 100.4 309.4 23.1 489.6 136.8 227.7 12.2 76.7 512.6 4.1 13.0 3.1 38.3 141.3 692.1 38.8 399.9 244.2 547.6 11.4 357.7 598.2 232.0 411.7 7.4 32.8 259.4 249.2 163.2 81.3 122.5 198.9 206.7 PTTG1 "EAP1, HPTTG, PTTG, securin, TUTR1" ENSG00000164611 "PTTG1 regulator of sister chromatid separation, securin" O95997 5 160421855-160428739 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, DNA damage, DNA repair, Mitosis" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 160.1;lymphoid tissue: 144.9;testis: 175.6" "Cell type enhanced" "Detected in many" "Early spermatids: 770.5;Erythroid cells: 415.9;Langerhans cells: 412.3;Spermatocytes: 708.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 218.0" "Lineage enriched" "Detected in all" 7 "T-cells: 218.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008373, HPA008890, HPA045034" Enhanced Supported Nucleoli,Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol Nucleoli "CAB008373: AB_592493, HPA008890: AB_1079717, HPA045034: AB_2679192" "unprognostic (6.48e-2)" "unprognostic (1.03e-2)" "unprognostic (1.40e-3)" "unprognostic (4.46e-3)" "unprognostic (5.81e-2)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.62e-6)" "unprognostic (7.50e-3)" "unprognostic (5.24e-2)" "unprognostic (3.47e-2)" "unprognostic (2.13e-3)" "unprognostic (6.70e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.17e-2)" "unprognostic (1.72e-1)" "unprognostic (4.23e-2)" "unprognostic (3.35e-2)" 3.7 3.5 4.2 25.2 5.3 160.1 10.9 4.1 11.5 9.6 4.0 33.9 24.6 4.8 9.6 59.7 5.0 6.1 3.5 8.1 6.6 3.0 5.3 8.7 81.5 3.9 4.8 1.8 1.5 2.3 4.3 21.2 4.2 3.1 44.1 2.4 10.3 2.7 2.5 36.0 24.1 19.2 4.0 18.6 11.8 175.6 5.3 127.0 79.3 1.3 144.9 12.5 19.9 4.7 345.4 178.2 385.8 279.5 64.4 63.3 120.8 177.5 406.1 463.4 503.5 341.1 294.9 373.3 154.7 204.2 527.5 176.1 243.5 496.1 661.2 428.3 220.3 196.7 241.8 208.6 13.0 181.5 165.6 29.6 81.5 315.4 189.5 139.9 333.4 243.3 160.7 282.3 485.4 162.3 220.7 446.1 197.5 279.3 251.4 199.4 452.4 320.7 239.6 82.6 241.0 151.3 258.6 156.3 535.6 309.3 319.9 195.7 144.8 208.3 275.9 164.9 531.3 239.2 235.6 432.3 225.9 310.4 379.6 9.7 3.2 10.3 25.5 8.7 9.6 30.9 52.3 60.6 23.9 23.5 12.7 31.4 3.0 14.6 5.8 22.6 218.0 19.8 4.2 5.3 4.1 11.5 8.1 6.6 3.9 4.8 4.2 4.0 5.3 4.7 11.8 6.4 21.5 0.0 40.0 247.9 64.5 163.6 142.3 3.4 15.8 40.5 4.0 4.3 31.1 5.5 0.0 125.4 38.3 17.7 3.9 5.8 770.5 22.7 9.3 20.6 6.0 415.9 1.3 5.3 196.2 35.6 28.1 16.7 37.5 66.2 18.5 7.1 87.5 0.0 1.6 39.2 126.1 36.3 412.3 105.1 11.1 39.1 87.2 0.0 24.7 3.5 6.2 0.0 0.6 3.0 10.7 7.9 91.4 54.1 9.0 2.0 17.1 1.0 6.6 18.6 43.2 708.0 57.3 232.0 156.1 31.9 73.7 16.8 70.3 50.3 PTTG1IP "C21orf1, C21orf3, PBF" ENSG00000183255 "PTTG1 interacting protein" P53801 21 44849585-44873903 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034146, HPA061827" Uncertain Supported Nucleoplasm NA Yes 26000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB034146: AB_1568894, HPA061827: AB_2684620" "unprognostic (1.78e-2)" "prognostic unfavorable (8.61e-4)" "unprognostic (5.24e-3)" "unprognostic (3.18e-2)" "unprognostic (1.68e-2)" "unprognostic (2.03e-2)" "unprognostic (3.59e-2)" "unprognostic (1.22e-2)" "unprognostic (1.98e-2)" "unprognostic (3.77e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (9.30e-2)" "unprognostic (3.17e-2)" "prognostic unfavorable (5.40e-4)" "unprognostic (1.38e-2)" "unprognostic (8.88e-2)" "unprognostic (1.90e-1)" 127.8 131.8 147.6 98.4 158.9 92.0 114.0 150.8 146.8 131.1 131.1 132.7 123.2 132.4 118.5 89.1 109.4 141.8 164.3 138.1 168.7 157.6 130.5 160.5 75.3 178.8 152.9 110.7 85.6 84.1 68.8 180.1 169.9 108.5 111.5 29.7 118.3 151.4 70.7 88.9 127.3 145.0 152.0 97.7 169.9 66.9 175.3 57.9 127.4 63.2 62.0 139.6 93.3 157.5 245.3 134.6 155.3 148.2 300.6 174.8 127.0 212.9 309.8 174.1 166.6 290.0 323.9 32.9 789.8 344.4 417.0 109.8 73.0 140.2 161.1 56.3 81.0 254.3 80.0 260.1 293.8 97.6 83.5 269.9 225.1 189.1 130.8 346.3 376.6 88.6 131.7 83.1 539.5 106.0 71.0 99.5 166.8 352.9 169.8 70.4 158.4 162.0 735.6 82.7 117.2 182.0 240.0 262.5 482.0 188.7 203.7 163.7 511.8 216.9 126.5 170.6 340.0 78.5 79.4 42.2 146.7 220.6 199.8 336.2 181.2 109.1 48.4 146.7 79.5 25.5 62.7 51.3 203.3 23.6 59.7 41.0 248.8 67.3 167.0 92.5 87.3 223.7 147.6 158.9 150.8 146.8 138.1 168.7 178.8 152.9 169.9 152.0 175.3 157.5 140.9 394.2 169.6 39.8 28.0 50.7 84.1 181.3 61.5 14.6 102.0 96.8 173.0 75.8 248.9 145.3 6.2 218.6 56.8 321.4 49.0 323.0 51.5 115.0 115.0 191.6 79.3 37.8 8.5 120.6 72.7 117.1 140.6 187.7 81.5 181.3 124.2 102.2 109.3 11.8 10.7 89.1 130.2 88.0 69.6 98.7 72.1 136.3 87.2 22.5 91.1 78.8 51.5 20.1 31.9 294.3 255.2 98.9 36.4 112.8 268.1 71.2 192.3 15.2 65.7 61.1 127.9 73.7 43.4 92.4 42.9 366.7 45.6 54.6 100.3 169.9 PYURF PreY ENSG00000145337 "PIGY upstream reading frame" Q96I23 4 88520998-88523776 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA036455 Uncertain Approved Nucleoplasm NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 32: Non-specific - Translation" Nucleoplasm "HPA036455: AB_10673388" "unprognostic (8.25e-2)" "unprognostic (9.14e-2)" "unprognostic (6.61e-2)" "unprognostic (2.03e-1)" "unprognostic (5.03e-2)" "unprognostic (7.23e-2)" "unprognostic (1.10e-2)" "unprognostic (8.84e-3)" "unprognostic (3.64e-1)" "unprognostic (1.48e-2)" "unprognostic (1.20e-2)" "unprognostic (2.35e-2)" "unprognostic (9.04e-3)" "unprognostic (1.59e-1)" "unprognostic (1.16e-1)" "unprognostic (1.01e-1)" "unprognostic (4.78e-3)" 71.2 72.2 35.1 23.1 37.0 44.5 70.4 38.7 43.4 69.0 33.8 72.0 30.7 74.8 45.6 64.1 65.5 22.5 58.6 34.0 37.3 84.9 81.7 56.4 27.8 36.7 35.6 65.2 59.0 41.9 66.2 28.5 36.5 61.9 31.2 22.9 55.4 33.9 66.9 67.0 53.9 36.2 39.2 54.4 56.8 42.3 36.2 27.3 54.5 42.3 29.4 61.7 62.5 39.3 60.1 19.8 39.1 46.4 76.7 78.3 26.2 43.2 60.6 53.1 44.6 15.5 46.3 0.2 47.3 61.7 36.4 25.2 35.6 54.4 66.6 73.4 61.8 66.2 24.8 59.9 58.0 110.7 40.9 54.4 80.8 34.5 69.5 50.4 88.5 20.4 75.9 64.9 77.8 45.5 68.5 67.6 32.7 70.5 37.5 68.0 36.3 69.8 44.4 33.4 46.7 45.7 54.9 49.4 119.9 38.4 23.0 54.8 60.6 56.1 51.9 55.3 40.6 45.6 40.1 7.5 49.3 55.7 63.1 82.4 92.1 79.0 90.4 94.9 102.2 98.9 103.2 98.3 111.0 80.5 105.4 101.6 18.1 108.9 95.3 68.3 116.8 186.1 35.1 37.0 38.7 43.4 34.0 37.3 36.7 35.6 36.5 39.2 36.2 39.3 136.2 51.3 71.3 0.0 92.0 230.4 176.0 167.2 158.8 28.7 207.2 205.2 5.8 84.4 98.8 86.5 10.4 232.3 106.8 65.5 287.6 118.0 44.0 69.7 103.9 127.0 114.6 98.2 0.0 129.5 120.6 119.6 53.5 51.2 105.8 97.7 114.2 147.3 139.4 26.9 0.0 99.4 101.7 115.9 124.7 98.3 125.9 100.0 348.6 0.0 129.2 113.3 176.1 0.0 0.0 103.4 102.7 120.0 84.6 208.7 128.0 236.9 79.1 33.0 59.2 107.3 109.2 108.1 62.3 189.9 289.0 163.9 119.6 136.5 132.8 142.3 RAC2 EN-7 ENSG00000128340 "Rac family small GTPase 2" P15153 22 37225270-37244448 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 411.9;lymphoid tissue: 387.9" "Cell type enhanced" "Detected in many" "B-cells: 329.0;dendritic cells: 381.4;granulocytes: 520.5;NK-cells: 717.9;Plasma cells: 287.8;T-cells: 419.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 522.5;HL-60: 734.5;HMC-1: 1427.9;Karpas-707: 684.5;U-87 MG: 618.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022946, HPA047820" Enhanced NA Yes 3300000 "Cluster 5: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB022946: , HPA047820: AB_2680167" "prognostic favorable (1.03e-5)" "unprognostic (2.91e-1)" "unprognostic (3.21e-2)" "unprognostic (1.82e-3)" "unprognostic (6.74e-2)" "unprognostic (7.78e-2)" "unprognostic (3.47e-1)" "unprognostic (5.00e-2)" "unprognostic (8.52e-3)" "unprognostic (2.65e-1)" "unprognostic (7.65e-2)" "unprognostic (3.81e-1)" "prognostic unfavorable (1.06e-6)" "unprognostic (1.45e-1)" "unprognostic (1.75e-1)" "unprognostic (6.21e-2)" "unprognostic (1.50e-2)" 24.7 8.4 3.6 207.2 3.8 411.9 11.4 3.9 8.0 12.2 4.4 34.8 35.3 10.1 4.7 15.9 11.7 37.1 6.5 3.8 4.7 10.9 19.3 63.4 387.9 6.5 5.3 5.5 5.3 2.1 3.4 12.4 7.1 10.9 33.9 0.4 21.5 8.3 4.9 7.6 96.9 19.6 5.2 299.9 42.7 3.5 6.1 323.9 9.5 7.2 309.1 54.0 9.9 7.2 136.6 0.2 0.0 0.0 14.3 130.5 0.6 17.9 41.1 14.2 28.8 0.3 44.8 167.4 19.8 52.9 0.8 33.3 1.0 231.6 15.6 522.5 0.6 209.6 3.6 0.6 35.8 734.5 1427.9 96.4 32.3 25.1 84.3 0.9 239.7 159.1 50.5 684.5 1.9 0.2 218.9 291.2 2.8 13.1 87.2 72.3 0.7 193.8 22.6 0.1 2.0 0.6 0.9 23.0 2.7 0.8 9.7 391.8 258.7 0.6 23.5 1.0 2.0 307.0 171.4 176.6 618.6 316.5 35.1 1319.9 519.8 1602.2 972.1 695.5 731.5 761.7 768.6 858.9 494.0 672.8 584.3 759.8 1336.4 972.2 879.5 728.7 1163.4 1566.2 3.6 3.8 3.9 8.0 3.8 4.7 6.5 5.3 7.1 5.2 6.1 7.2 4.4 16.0 47.7 0.0 329.0 5.4 2.2 26.0 16.5 0.0 8.6 9.5 1.1 2.8 12.6 1.8 0.0 0.8 381.4 3.4 0.0 13.6 0.2 1.1 0.8 5.6 4.2 109.7 0.4 2.2 1.5 9.2 33.6 1.0 520.5 0.3 13.6 3.4 150.8 0.0 0.1 6.3 0.0 129.9 63.9 0.9 0.3 147.9 30.2 3.7 125.9 0.0 717.9 0.5 0.0 18.2 18.1 0.0 287.8 0.5 0.6 1.5 4.4 0.0 13.1 2.4 4.5 0.0 1.0 5.1 4.0 2.9 419.6 3.7 11.2 3.6 RAD1 "HRAD1, REC1" ENSG00000113456 "RAD1 checkpoint DNA exonuclease" O60671 5 34905260-34918989 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006692 Approved Approved Nucleoplasm,Vesicles NA Yes "Cluster 6: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 20: HeLa - Mitochondria" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Vesicles" "HPA006692: AB_2667645" "prognostic unfavorable (6.30e-4)" "unprognostic (1.85e-2)" "unprognostic (9.40e-2)" "unprognostic (1.98e-3)" "unprognostic (2.00e-1)" "unprognostic (2.38e-2)" "prognostic unfavorable (1.06e-5)" "unprognostic (1.22e-2)" "unprognostic (2.25e-3)" "unprognostic (1.61e-3)" "unprognostic (2.57e-1)" "unprognostic (2.57e-1)" "unprognostic (2.22e-2)" "unprognostic (1.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.11e-1)" "unprognostic (3.12e-3)" 3.5 8.1 3.2 4.8 3.5 8.4 5.8 3.9 4.6 6.8 5.3 4.1 4.9 5.6 5.4 4.9 3.9 4.6 8.9 3.8 4.6 5.1 4.3 7.5 8.9 3.5 2.7 5.7 4.4 5.1 3.5 8.1 3.2 6.8 4.3 8.7 4.9 4.8 10.9 6.7 4.8 4.6 1.9 4.9 4.8 7.9 3.4 6.3 6.3 8.6 6.2 5.2 4.7 3.8 8.5 10.2 12.3 20.5 7.9 9.4 17.2 15.1 12.0 13.0 10.6 12.2 12.3 25.0 5.2 11.2 15.7 8.4 12.6 7.6 14.4 10.1 12.7 12.9 34.0 8.0 11.9 16.5 11.9 7.8 7.3 13.9 9.3 6.1 6.2 11.0 22.7 13.2 11.2 10.2 19.6 13.9 15.4 6.0 15.7 17.1 24.0 8.6 6.7 9.0 12.4 13.3 30.0 19.9 13.3 7.6 12.5 14.8 6.2 17.9 13.3 9.7 14.4 7.9 13.8 20.3 11.1 28.6 12.5 7.4 2.9 6.5 5.3 2.8 6.9 8.6 5.8 7.6 3.1 9.1 8.2 6.8 1.6 4.5 2.8 6.9 4.9 2.6 3.2 3.5 3.9 4.6 3.8 4.6 3.5 2.7 3.2 1.9 3.4 3.8 11.5 22.4 43.2 5.9 18.3 29.2 20.2 29.3 13.1 25.3 23.9 18.4 25.7 14.3 21.3 20.2 27.1 82.3 20.4 11.9 19.6 18.1 22.0 13.1 16.6 14.1 13.1 28.2 6.6 22.5 54.4 18.7 6.1 12.0 21.5 39.1 10.0 14.8 23.4 23.5 9.0 12.7 30.5 12.0 19.3 16.8 25.1 13.1 17.8 6.5 12.7 23.9 9.2 7.5 9.1 17.8 13.8 21.8 18.0 21.9 13.4 16.4 14.6 35.6 13.1 19.6 19.4 72.5 58.6 15.6 28.6 80.6 22.3 27.4 13.0 25.8 RAD18 RNF73 ENSG00000070950 "RAD18 E3 ubiquitin protein ligase" Q9NS91 3 8775402-8963773 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006716, HPA006724, HPA008752" Supported Approved Enhanced "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nuclear bodies" "HPA006716: AB_2667650, HPA006724: AB_2667655, HPA008752: AB_2668129" "unprognostic (1.26e-1)" "unprognostic (1.07e-1)" "unprognostic (4.45e-2)" "unprognostic (1.25e-3)" "unprognostic (2.73e-2)" "unprognostic (6.15e-2)" "prognostic unfavorable (1.12e-4)" "unprognostic (2.01e-1)" "unprognostic (9.76e-2)" "unprognostic (1.17e-1)" "unprognostic (2.02e-2)" "prognostic unfavorable (3.73e-4)" "prognostic unfavorable (3.65e-5)" "unprognostic (1.97e-2)" "unprognostic (1.51e-1)" "unprognostic (7.92e-2)" "unprognostic (1.89e-2)" 2.7 2.3 1.2 3.3 1.5 5.2 5.3 1.3 1.7 3.2 0.5 3.8 10.1 2.8 1.9 3.4 2.3 3.1 1.8 1.5 0.9 1.6 2.7 2.7 4.6 1.6 1.0 2.8 1.7 2.0 1.3 3.0 1.5 3.2 4.9 2.6 3.2 1.6 1.3 4.5 6.5 2.8 1.2 3.5 2.2 2.9 1.1 5.8 3.7 1.0 4.4 2.5 2.9 2.3 16.2 15.2 12.3 7.4 3.0 6.4 14.9 25.0 8.5 23.5 16.1 13.7 10.1 19.8 4.7 14.2 13.8 5.6 13.1 13.0 23.8 12.2 17.2 16.9 16.1 8.2 1.9 22.7 13.9 2.4 4.6 23.3 15.7 6.3 7.7 17.1 18.2 19.0 20.9 18.6 22.9 15.9 17.2 12.7 28.5 18.0 13.6 15.6 6.9 12.2 5.1 11.5 11.2 10.5 8.2 9.7 11.0 9.8 6.4 19.4 10.5 16.8 21.7 9.6 16.1 43.7 14.3 24.5 14.6 6.4 1.6 5.1 1.5 1.7 2.8 1.9 2.1 2.7 2.0 1.9 2.2 1.6 0.7 2.8 1.1 3.6 3.0 0.8 1.2 1.5 1.3 1.7 1.5 0.9 1.6 1.0 1.5 1.2 1.1 2.3 5.7 16.0 9.8 6.2 7.7 11.1 7.5 6.4 5.7 4.6 7.3 11.7 2.2 4.3 7.5 3.7 2.1 9.0 8.6 5.2 1.9 9.6 4.2 4.0 5.8 4.6 1.8 7.2 20.9 8.2 12.4 6.8 3.6 4.9 13.9 14.8 6.1 3.1 7.1 3.3 15.7 6.5 2.0 5.2 5.6 3.0 4.1 4.6 3.6 14.0 7.1 3.2 8.2 16.1 14.3 10.2 4.3 2.6 8.7 6.4 4.0 3.1 4.1 2.3 6.6 4.3 6.9 26.2 14.0 6.0 11.8 6.7 7.5 9.3 6.3 3.6 RAD21 "hHR21, KIAA0078, SCC1" ENSG00000164754 "RAD21 cohesin complex component" O60216 8 116845934-116874776 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Activator, Developmental protein, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 424.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020044, CAB022065, HPA073277" Supported Enhanced Nucleoplasm NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "CAB022065: , HPA020044: AB_1856035, HPA073277: " "unprognostic (7.85e-2)" "unprognostic (4.92e-1)" "unprognostic (3.05e-1)" "unprognostic (5.43e-3)" "unprognostic (9.56e-2)" "unprognostic (3.50e-1)" "prognostic unfavorable (1.71e-4)" "unprognostic (1.86e-3)" "unprognostic (8.99e-2)" "unprognostic (8.80e-2)" "unprognostic (5.58e-3)" "unprognostic (3.56e-2)" "unprognostic (4.40e-2)" "unprognostic (2.00e-1)" "unprognostic (1.82e-1)" "unprognostic (1.39e-1)" "unprognostic (1.95e-1)" 75.4 80.5 62.9 74.0 74.5 206.0 71.9 74.7 75.7 50.5 56.7 73.1 57.3 67.6 54.6 71.2 50.6 49.4 89.8 58.1 74.3 68.2 64.7 67.9 122.8 70.0 69.3 67.8 41.9 82.3 33.8 90.1 75.2 57.5 82.5 114.2 56.9 65.0 76.6 54.0 60.4 60.2 71.9 75.5 56.4 88.7 67.2 177.2 80.9 95.5 119.5 59.7 44.5 97.1 301.6 143.9 277.3 156.7 136.5 117.0 124.2 202.1 191.4 220.8 202.4 119.8 275.2 438.6 109.4 146.0 117.4 162.4 238.5 132.1 257.6 589.1 153.1 447.6 167.2 153.7 85.5 145.7 253.1 100.2 106.0 129.4 156.0 146.1 176.4 625.8 183.6 595.6 193.1 181.1 665.4 86.2 163.6 385.4 179.2 241.8 201.5 223.4 133.5 173.3 348.2 179.1 212.2 569.4 140.6 144.5 238.3 178.5 128.5 154.6 223.5 164.4 217.1 313.3 383.9 391.9 132.8 206.7 189.7 35.3 7.9 28.0 17.4 8.7 17.5 14.4 20.3 20.6 9.0 12.8 20.8 20.6 29.7 14.3 12.7 7.6 43.7 11.4 62.9 74.5 74.7 75.7 58.1 74.3 70.0 69.3 75.2 71.9 67.2 97.1 115.7 256.4 157.1 24.5 111.2 95.6 77.5 62.5 78.0 75.4 65.8 53.0 155.2 51.5 101.0 55.2 31.3 142.4 118.1 90.4 43.0 54.0 258.0 67.0 86.7 97.0 84.4 249.8 39.3 44.9 157.0 89.4 57.1 88.2 153.5 112.9 75.0 72.1 67.9 67.3 48.1 72.7 69.2 93.1 100.0 424.9 116.5 93.4 69.4 45.9 110.8 112.5 77.2 41.2 58.3 63.5 66.3 106.5 124.0 100.0 35.7 59.4 70.5 67.9 72.3 88.6 85.3 33.2 88.6 103.7 100.4 113.7 134.1 85.5 94.1 95.5 RAD51 "BRCC5, FANCR, HsRad51, HsT16930, RAD51A, RECA" ENSG00000051180 "RAD51 recombinase" Q06609 15 40694774-40732340 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.7;testis: 24.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 35.3;Extravillous trophoblasts: 67.2;Spermatocytes: 53.6;Spermatogonia: 24.8;Syncytiotrophoblasts: 25.3" "Cancer enhanced" "Detected in all" "testis cancer: 19.9" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB010381, HPA039310" Enhanced Supported "Nucleoli rim,Cytosol" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoli rim" Cytosol "CAB010381: AB_2253533, HPA039310: AB_2676434" "prognostic unfavorable (7.94e-4)" "unprognostic (7.20e-3)" "unprognostic (1.22e-1)" "unprognostic (2.72e-2)" "unprognostic (8.23e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (9.33e-4)" "unprognostic (3.40e-3)" "unprognostic (2.53e-2)" "unprognostic (1.76e-1)" "unprognostic (1.41e-3)" "unprognostic (2.53e-3)" "unprognostic (0.00e+0)" "unprognostic (2.26e-2)" "unprognostic (2.34e-1)" "unprognostic (9.59e-2)" "unprognostic (1.94e-2)" 0.9 0.6 0.4 5.5 0.5 10.5 1.9 1.7 0.7 1.0 0.6 8.3 3.2 1.2 0.4 4.2 0.7 1.3 0.6 0.4 0.5 0.5 1.3 1.1 11.0 0.4 0.3 0.6 1.4 0.5 0.2 6.8 0.5 0.8 9.1 0.3 1.0 0.3 1.0 3.1 4.1 2.4 0.1 2.4 1.8 24.3 0.3 15.7 0.6 0.5 13.3 1.7 1.5 0.5 33.8 16.1 33.4 16.3 4.4 7.8 31.1 54.9 16.5 43.3 43.8 35.4 22.1 20.4 26.8 20.9 18.9 67.7 56.6 22.1 42.3 39.0 22.2 47.7 28.2 30.4 0.4 37.9 28.5 1.7 2.9 30.0 13.5 6.4 22.5 48.5 59.6 55.8 36.6 28.5 54.4 43.6 35.2 69.2 19.0 61.0 49.0 30.7 15.4 45.3 15.4 27.0 23.6 41.4 8.5 39.2 27.0 39.4 9.9 32.8 22.2 48.7 27.2 12.0 65.1 59.8 16.3 78.0 33.5 1.3 0.6 1.7 2.4 1.3 0.6 1.7 2.5 3.2 1.0 1.1 0.6 1.2 1.2 1.8 1.4 0.9 5.9 1.2 0.4 0.5 1.7 0.7 0.4 0.5 0.4 0.3 0.5 0.1 0.3 0.5 0.0 0.0 0.0 0.3 1.9 3.6 1.5 2.0 0.0 0.8 0.1 0.0 0.9 0.0 1.0 0.0 0.0 35.3 1.4 3.0 0.0 0.0 5.7 0.2 0.2 1.0 0.0 16.0 1.6 0.0 67.2 1.3 2.0 0.2 0.0 0.6 2.2 0.2 12.7 0.0 1.2 5.3 2.0 1.6 1.7 5.3 0.6 0.5 0.0 1.0 0.3 0.3 2.1 0.5 0.6 0.1 5.0 0.7 8.2 0.9 1.0 0.0 0.1 0.0 0.0 0.5 0.9 53.6 24.8 3.9 1.6 25.3 1.2 0.1 8.0 2.1 RASAL2 nGAP ENSG00000075391 "RAS protein activator like 2" Q9UJF2 1 178094104-178484147 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 28.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 505.8;Inhibitory neurons: 398.4;Microglial cells: 271.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 54.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018805, HPA020453" Enhanced Approved "Plasma membrane,Focal adhesion sites" NA Yes "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Focal adhesion sites" "HPA018805: AB_1856085, HPA020453: AB_1856086" "unprognostic (5.55e-3)" "unprognostic (6.49e-2)" "unprognostic (2.65e-1)" "unprognostic (6.33e-2)" "unprognostic (3.40e-2)" "unprognostic (5.59e-2)" "unprognostic (5.91e-2)" "unprognostic (1.72e-2)" "unprognostic (2.91e-1)" "unprognostic (2.92e-2)" "unprognostic (3.16e-3)" "unprognostic (2.03e-1)" "unprognostic (1.06e-2)" "unprognostic (4.98e-2)" "unprognostic (2.45e-1)" "unprognostic (8.36e-2)" "prognostic unfavorable (2.05e-4)" 10.3 3.6 1.7 2.8 3.2 0.6 8.0 0.0 7.4 7.3 0.1 4.2 2.7 6.1 3.6 17.0 5.5 7.5 13.6 4.3 0.8 5.8 3.0 9.4 1.8 0.0 1.0 3.6 4.6 4.6 5.9 9.4 0.0 5.0 4.4 28.9 6.6 4.4 4.6 7.0 3.4 6.6 0.0 3.2 3.7 8.9 5.1 1.8 5.3 10.0 2.9 5.0 10.5 2.4 30.9 8.9 12.1 4.2 8.6 11.6 17.3 13.2 13.6 11.7 8.5 14.8 15.6 0.0 23.0 13.2 19.7 25.2 10.2 23.0 10.7 0.0 5.0 0.0 9.8 7.1 10.0 4.7 0.5 35.1 5.2 13.4 54.1 13.7 10.3 0.0 1.0 0.0 16.5 3.2 0.0 4.2 10.1 6.4 1.8 0.1 5.2 0.0 7.2 3.6 8.8 4.4 10.9 9.5 9.0 10.8 10.4 5.5 18.9 15.1 15.7 17.2 21.0 6.5 0.1 0.1 13.3 2.4 11.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.7 3.2 0.0 7.4 4.3 0.8 0.0 1.0 0.0 0.0 5.1 2.4 99.8 76.9 12.9 47.3 1.0 15.9 10.0 15.7 8.0 50.7 17.8 11.7 37.4 17.2 18.2 16.5 152.2 15.0 1.0 9.0 5.9 21.8 17.4 33.6 43.0 66.2 34.1 0.0 505.8 12.5 16.4 18.4 17.9 27.6 7.6 19.0 35.3 6.7 16.8 84.1 398.4 15.7 6.1 4.5 21.6 7.3 19.6 16.5 3.6 271.7 8.5 24.7 0.0 154.3 101.3 33.6 5.2 23.0 2.9 32.6 4.9 6.6 34.7 175.5 65.7 22.7 56.9 40.5 34.5 17.8 24.2 41.9 2.3 8.3 12.6 38.2 RBBP8 "COM1, CtIP, RIM, SCKL2" ENSG00000101773 "RB binding protein 8, endonuclease" Q99708 18 22798261-23026488 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "DNA-binding, Endonuclease, Hydrolase, Nuclease" "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 125.9;Spermatocytes: 116.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 36.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039890, HPA052946" Approved Supported Nucleoplasm NA Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" Nucleoplasm "HPA039890: AB_10794756, HPA052946: AB_2681996" "unprognostic (1.55e-3)" "unprognostic (4.10e-3)" "unprognostic (7.89e-2)" "unprognostic (1.01e-1)" "unprognostic (2.44e-1)" "unprognostic (7.28e-2)" "unprognostic (3.60e-3)" "unprognostic (1.87e-1)" "prognostic unfavorable (7.21e-4)" "unprognostic (2.29e-2)" "unprognostic (1.58e-3)" "unprognostic (1.04e-2)" "prognostic favorable (1.71e-5)" "unprognostic (3.91e-3)" "unprognostic (2.42e-2)" "unprognostic (1.01e-2)" "unprognostic (4.48e-1)" 10.1 8.7 6.8 10.0 6.8 18.2 29.4 9.2 11.3 20.9 41.6 14.5 9.3 20.1 23.4 22.1 28.0 12.7 7.0 7.4 9.2 42.2 14.4 13.5 14.0 6.3 7.3 6.4 18.5 22.1 17.5 8.5 6.4 10.8 12.9 6.2 19.5 23.3 2.3 28.5 12.9 16.4 6.2 7.6 13.1 28.7 8.5 32.4 18.2 3.5 17.3 18.3 18.0 7.3 32.9 24.8 36.0 41.9 18.2 19.4 28.2 44.2 31.1 40.3 56.5 45.7 36.3 95.4 19.9 27.9 38.5 67.3 41.2 89.9 78.5 68.3 33.2 41.8 32.0 44.0 22.2 151.5 43.7 13.9 86.0 61.0 105.3 23.6 16.6 65.7 25.0 69.2 41.6 49.1 112.8 50.6 34.2 60.1 41.5 57.6 65.9 58.9 117.4 34.7 84.1 39.8 74.1 22.4 39.0 20.5 129.1 39.4 12.0 107.2 49.3 52.4 78.0 92.9 108.4 105.3 49.1 72.2 58.8 17.0 6.5 3.9 1.2 24.0 0.5 6.6 1.7 2.1 8.2 5.3 0.9 1.5 2.4 7.9 36.7 8.1 4.7 3.8 6.8 6.8 9.2 11.3 7.4 9.2 6.3 7.3 6.4 6.2 8.5 7.3 13.1 35.3 42.8 10.1 22.9 27.4 44.7 125.9 76.8 4.3 22.6 72.6 10.4 35.8 41.9 29.5 4.2 12.7 25.0 14.5 43.0 30.5 17.7 56.0 19.5 14.2 7.7 37.0 20.3 33.0 9.4 13.2 23.0 67.3 66.1 22.3 5.7 16.4 11.7 1.7 15.5 9.3 16.2 11.4 23.5 14.5 6.5 27.5 23.2 8.4 9.0 2.1 4.1 9.5 2.7 44.9 8.6 5.3 53.8 37.5 17.5 26.1 28.2 7.9 0.0 20.4 14.0 116.6 83.4 36.2 19.7 15.2 13.6 9.8 14.9 45.5 REEP4 "C8orf20, FLJ22246, FLJ22277, PP432, Yip2c" ENSG00000168476 "Receptor accessory protein 4" Q9H6H4 8 22138020-22141951 "Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 89.3;skin 1: 91.0" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 94.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042683 Approved Supported "Endoplasmic reticulum" No Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Endoplasmic reticulum" "HPA042683: AB_2571730" "unprognostic (2.38e-1)" "unprognostic (9.96e-3)" "unprognostic (3.35e-2)" "unprognostic (2.38e-2)" "unprognostic (3.41e-2)" "unprognostic (7.75e-2)" "prognostic unfavorable (4.14e-5)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.91e-1)" "unprognostic (7.15e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.88e-5)" "unprognostic (5.72e-2)" "unprognostic (1.06e-1)" "unprognostic (2.25e-1)" "unprognostic (6.65e-2)" 13.0 8.4 7.0 12.5 8.7 28.4 11.6 8.7 9.7 27.9 7.6 23.8 11.0 9.4 2.1 89.3 11.1 5.6 8.0 6.8 8.2 9.2 12.3 18.0 11.2 10.8 8.5 7.4 12.9 5.0 10.9 14.6 10.5 13.6 10.8 2.1 21.8 6.5 4.1 91.0 16.9 5.9 9.0 33.2 18.0 42.7 9.5 9.9 14.8 2.6 10.2 19.6 49.0 11.5 42.2 79.7 24.9 39.7 10.5 10.6 47.9 36.7 19.2 44.6 40.2 46.7 38.8 53.0 46.8 18.4 38.5 100.3 29.6 59.3 21.9 28.2 37.4 57.4 41.2 46.9 11.8 25.8 77.9 9.8 110.3 33.3 27.5 13.9 27.1 58.1 44.5 158.7 22.6 60.6 63.7 88.9 37.4 58.0 53.3 37.0 22.5 101.8 19.9 40.0 21.7 40.1 30.0 31.7 52.7 16.5 64.3 35.9 30.5 29.2 50.1 66.6 50.3 40.0 33.5 34.6 32.6 54.7 59.1 49.8 54.8 64.1 24.3 53.6 19.6 10.5 21.1 21.1 42.7 4.9 9.7 13.1 15.5 26.3 37.0 16.9 15.4 27.6 7.0 8.7 8.7 9.7 6.8 8.2 10.8 8.5 10.5 9.0 9.5 11.5 6.8 3.2 9.2 4.9 7.9 28.0 15.1 45.5 15.4 6.5 5.8 5.7 1.8 7.2 21.9 12.9 2.1 54.0 13.8 27.3 0.0 21.9 16.0 3.8 4.9 9.2 17.4 48.2 0.7 15.0 50.4 8.1 21.9 5.9 10.2 14.0 15.4 6.6 55.4 0.0 0.6 33.0 22.4 38.8 21.5 9.4 9.0 26.1 3.6 10.3 16.5 1.8 10.3 1.0 2.6 25.6 34.7 8.2 19.3 19.0 19.2 1.9 8.1 1.5 13.1 2.3 9.7 61.0 17.9 41.1 39.2 94.1 13.5 8.9 31.1 24.5 RFC2 "A1, RFC40" ENSG00000049541 "Replication factor C subunit 2" P35250 7 74231499-74254458 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA replication" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 68.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029493 Approved Supported "Nucleoplasm,Golgi apparatus" NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus" "HPA029493: AB_10603991" "unprognostic (1.25e-1)" "prognostic favorable (9.91e-4)" "unprognostic (1.44e-1)" "unprognostic (7.66e-3)" "unprognostic (1.17e-2)" "unprognostic (1.93e-1)" "prognostic unfavorable (6.35e-4)" "unprognostic (2.08e-2)" "unprognostic (5.74e-2)" "unprognostic (2.35e-2)" "unprognostic (5.57e-2)" "unprognostic (2.79e-2)" "prognostic unfavorable (2.09e-7)" "unprognostic (2.22e-1)" "unprognostic (6.65e-2)" "unprognostic (3.61e-2)" "unprognostic (2.59e-1)" 12.2 9.5 10.6 13.4 10.9 27.4 15.5 11.4 11.5 12.6 11.1 13.4 9.0 9.6 8.4 18.6 10.1 8.6 10.1 10.5 10.9 14.7 21.2 11.3 23.5 11.7 11.3 11.3 13.3 11.8 7.9 18.4 11.4 11.5 15.0 8.8 12.2 7.6 18.8 20.3 11.2 12.6 11.5 14.2 13.6 10.0 10.7 20.2 9.2 12.2 30.8 11.5 12.6 11.8 74.3 55.6 65.2 64.6 13.1 15.2 29.4 42.5 46.7 85.2 101.4 62.6 67.3 69.2 11.5 30.7 78.7 49.7 53.3 69.2 87.5 49.6 91.5 42.9 76.4 46.7 10.1 64.6 25.3 15.4 15.9 79.8 55.0 18.5 46.0 63.9 89.4 41.9 66.4 87.2 65.1 124.7 74.1 116.3 47.4 95.0 72.0 85.8 45.7 58.1 52.4 65.5 50.7 94.8 34.7 79.2 68.7 58.0 17.4 83.4 54.9 64.6 96.3 25.1 35.1 120.6 42.4 98.4 89.3 33.4 36.7 27.3 18.0 42.3 18.1 31.6 15.5 16.5 31.9 36.8 19.5 14.3 46.4 42.9 40.1 17.1 23.9 29.1 10.6 10.9 11.4 11.5 10.5 10.9 11.7 11.3 11.4 11.5 10.7 11.8 15.4 12.8 11.1 2.6 19.0 23.8 24.3 24.3 19.9 13.2 12.6 17.4 6.1 5.7 16.5 5.5 2.1 68.6 17.5 12.4 5.9 21.0 2.8 8.1 13.3 13.5 4.8 38.3 3.0 19.0 65.0 17.4 10.7 11.5 23.4 25.1 13.6 14.0 37.7 3.3 2.6 13.1 20.3 14.4 28.2 2.5 8.7 18.2 21.4 1.9 26.3 16.1 23.7 1.5 2.2 13.8 6.9 10.9 17.5 11.0 13.2 13.8 8.8 9.5 6.6 14.6 17.5 33.8 44.6 20.1 17.0 46.1 16.9 12.9 19.1 15.3 RFC3 "MGC5276, RFC38" ENSG00000133119 "Replication factor C subunit 3" P40938 13 33818069-33966558 "Predicted intracellular proteins" "DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 285.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030149 Approved Supported Nucleoplasm,Vesicles No Yes "Cluster 27: Non-specific - Gene expression" "Cluster 63: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Vesicles" "HPA030149: AB_10602921" "unprognostic (3.86e-2)" "unprognostic (5.27e-2)" "unprognostic (1.12e-1)" "unprognostic (1.16e-2)" "unprognostic (5.76e-2)" "unprognostic (3.07e-3)" "unprognostic (3.32e-2)" "unprognostic (4.93e-2)" "unprognostic (9.02e-3)" "unprognostic (4.49e-1)" "unprognostic (6.46e-2)" "unprognostic (4.05e-2)" "unprognostic (5.24e-3)" "unprognostic (4.05e-2)" "unprognostic (1.79e-1)" "unprognostic (5.08e-2)" "unprognostic (2.86e-1)" 5.3 13.8 2.6 12.9 2.4 19.5 12.8 8.7 2.6 5.7 1.7 9.0 8.5 10.6 4.3 6.7 8.3 4.6 6.1 2.7 2.5 5.1 7.4 5.4 24.3 2.7 2.2 7.8 4.8 5.1 2.6 10.8 2.8 6.3 11.6 5.9 5.5 4.1 3.5 7.5 7.9 7.6 3.7 6.6 6.5 12.8 2.6 24.1 6.5 4.4 23.4 5.7 4.6 2.5 49.0 51.1 86.4 69.5 6.5 10.0 47.5 66.6 29.2 85.5 73.7 63.0 72.2 179.8 26.8 25.3 53.2 72.5 111.6 45.9 112.0 71.5 68.9 105.0 54.4 68.0 7.5 127.2 48.3 9.8 5.8 74.5 49.9 14.1 28.9 63.7 75.1 44.2 51.4 56.1 108.8 58.1 104.2 101.2 42.1 40.3 103.4 41.1 25.4 42.7 45.1 79.2 49.4 65.3 33.4 45.7 52.2 66.8 15.5 45.1 49.7 57.1 70.9 24.9 36.7 285.3 32.4 73.7 86.6 1.5 4.4 7.2 3.2 6.1 3.7 5.8 3.9 3.3 6.1 5.5 5.0 4.5 0.9 2.5 5.3 2.5 6.3 3.1 2.6 2.4 8.7 2.6 2.7 2.5 2.7 2.2 2.8 3.7 2.6 2.5 9.3 9.6 6.2 5.9 11.2 12.2 6.9 6.9 7.4 16.5 8.9 10.5 7.5 1.5 8.6 3.7 8.4 29.6 5.1 3.0 3.9 7.3 8.4 7.0 7.9 9.4 6.1 43.8 30.2 8.9 39.3 7.5 3.1 7.7 1.3 17.8 8.9 7.2 11.9 8.4 20.3 4.3 4.1 6.7 4.0 7.9 6.2 6.5 8.8 34.7 6.4 5.4 1.0 33.7 18.0 5.4 1.5 4.5 21.0 2.7 1.1 5.4 3.8 12.2 6.6 7.9 29.8 52.6 43.2 9.2 7.0 16.4 6.6 9.2 10.1 3.3 RFC4 "A1, RFC37" ENSG00000163918 "Replication factor C subunit 4" P35249 3 186789880-186807058 "Plasma proteins, Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 55.7;Spermatocytes: 86.7;Spermatogonia: 50.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004557, HPA049123, HPA058507" Enhanced Enhanced Nucleoplasm NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB004557: AB_2178593, HPA049123: AB_2680642, HPA058507: AB_2683736" "unprognostic (2.45e-1)" "prognostic favorable (7.41e-5)" "unprognostic (2.84e-1)" "unprognostic (1.81e-3)" "unprognostic (1.03e-1)" "unprognostic (6.69e-3)" "prognostic unfavorable (6.75e-7)" "unprognostic (5.29e-3)" "unprognostic (1.15e-2)" "unprognostic (2.34e-3)" "prognostic unfavorable (7.38e-4)" "unprognostic (5.92e-2)" "prognostic unfavorable (2.22e-16)" "unprognostic (1.80e-2)" "unprognostic (4.98e-1)" "unprognostic (6.15e-2)" "unprognostic (2.16e-1)" 7.0 6.0 7.3 19.3 7.6 41.5 13.8 8.9 11.9 8.8 7.4 15.4 10.9 14.1 6.6 11.8 10.8 7.7 9.1 7.5 7.5 7.3 10.7 7.2 31.5 7.3 7.4 15.0 11.0 8.0 5.7 14.5 7.6 7.7 20.4 11.2 8.6 7.0 8.3 11.7 11.7 17.6 7.5 14.3 10.4 22.7 8.1 35.7 7.3 6.7 34.5 7.8 8.2 8.3 167.3 56.2 130.8 83.6 18.8 20.1 103.0 78.9 49.9 123.6 135.8 84.8 77.9 119.5 177.4 38.0 118.0 86.1 116.5 77.5 151.1 180.5 102.5 123.3 86.3 86.3 14.6 131.8 79.5 17.3 27.5 84.9 66.1 27.6 42.0 183.8 97.9 165.4 85.3 79.7 167.2 122.8 116.0 148.1 76.0 129.9 112.5 164.3 44.9 60.7 126.3 63.3 97.3 107.6 90.3 97.6 183.0 123.7 19.6 74.4 93.3 125.8 239.9 91.9 216.9 398.9 65.3 142.8 100.0 0.0 2.8 9.7 11.5 4.2 11.1 13.1 11.4 12.0 5.0 15.1 11.2 10.2 0.6 9.8 14.7 9.6 21.8 7.7 7.3 7.6 8.9 11.9 7.5 7.5 7.3 7.4 7.6 7.5 8.1 8.3 5.1 0.0 2.2 3.3 14.0 6.0 15.3 18.1 5.2 16.1 4.1 8.1 7.5 5.7 9.3 11.0 0.0 43.0 9.7 4.4 5.9 15.3 27.3 5.6 7.0 6.1 1.2 46.3 5.2 16.6 55.7 8.3 6.6 6.0 8.2 25.3 6.1 3.0 23.9 8.4 4.4 7.1 10.2 2.6 4.9 10.0 10.5 6.2 1.8 4.7 12.2 14.9 9.2 2.5 4.3 9.2 4.1 7.9 23.8 3.8 2.8 7.9 7.9 14.4 6.6 10.2 13.1 86.7 50.5 7.9 3.0 11.2 9.6 8.8 13.9 4.7 RMI1 "BLAP75, C9orf76, FLJ12888" ENSG00000178966 "RecQ mediated genome instability 1" Q9H9A7 9 83980798-84004074 "Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 70.0;Late spermatids: 62.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021661 Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nuclear bodies" "HPA021661: " "unprognostic (9.59e-2)" "unprognostic (7.96e-2)" "unprognostic (6.72e-3)" "unprognostic (3.03e-2)" "unprognostic (1.47e-1)" "unprognostic (2.90e-2)" "prognostic unfavorable (8.71e-4)" "unprognostic (2.65e-1)" "unprognostic (3.39e-3)" "unprognostic (1.32e-1)" "unprognostic (5.55e-2)" "unprognostic (2.26e-1)" "unprognostic (1.53e-1)" "unprognostic (3.68e-3)" "unprognostic (3.42e-1)" "unprognostic (2.42e-1)" "unprognostic (9.24e-2)" 2.5 8.3 2.9 6.0 3.2 3.9 4.5 4.6 3.4 3.2 6.0 6.6 6.2 3.5 5.6 4.9 5.8 2.8 3.4 2.4 5.8 4.4 5.8 3.3 10.2 3.3 3.3 4.4 5.8 7.7 3.7 3.6 3.5 4.8 7.4 7.0 6.0 3.1 3.7 5.1 6.8 3.3 3.2 6.4 6.2 8.9 3.8 10.2 6.0 3.9 9.6 3.6 2.4 3.8 25.2 14.9 33.6 12.4 5.5 7.7 33.9 24.1 13.6 20.7 19.4 7.5 17.0 55.4 8.5 12.4 21.7 36.9 22.0 12.3 25.3 29.2 6.1 23.0 12.1 11.8 7.7 42.6 23.1 7.4 7.8 17.6 12.6 6.7 11.1 28.2 16.7 26.3 23.2 18.1 54.4 17.4 31.3 31.6 15.7 47.8 33.9 21.0 10.8 10.4 30.4 19.3 21.3 18.6 9.8 15.4 19.4 20.8 6.6 22.9 14.7 23.2 20.1 11.6 25.6 20.2 14.6 19.7 26.4 14.2 4.5 8.8 1.8 5.5 2.2 2.8 2.1 1.9 7.2 2.6 2.2 2.5 7.8 2.8 6.5 2.2 3.0 2.6 2.9 3.2 4.6 3.4 2.4 5.8 3.3 3.3 3.5 3.2 3.8 3.8 5.4 9.6 5.1 10.1 5.9 2.7 3.2 4.3 4.0 4.1 4.3 3.3 8.5 2.8 9.0 1.8 4.2 7.9 2.1 6.1 5.9 5.5 70.0 13.9 6.5 3.8 6.7 24.4 7.1 3.0 16.2 3.3 8.2 10.2 4.5 9.0 5.0 13.3 8.1 10.1 11.2 9.8 0.0 10.7 4.3 62.1 2.1 7.4 12.4 8.4 8.5 7.7 5.2 26.2 12.6 2.7 5.6 2.2 7.8 4.2 8.9 4.9 11.1 5.2 0.0 3.3 3.4 34.0 22.6 6.9 4.8 4.2 4.4 7.7 10.1 2.4 RMI2 "BLAP18, C16orf75, MGC24665" ENSG00000175643 "RecQ mediated genome instability 2" Q96E14 16 11249619-11381662 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 36.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 123.8;Erythroid cells: 38.5;Extravillous trophoblasts: 34.1;Peritubular cells: 42.5;Spermatocytes: 36.6;Spermatogonia: 51.8;Syncytiotrophoblasts: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 4.2" "Group enriched" "Detected in many" 6 "B-cells: 4.2;T-cells: 1.4" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA040995 Uncertain Supported "Nuclear speckles,Cytosol" NA Yes "Cluster 37: B-cells - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear speckles" Cytosol "HPA040995: AB_10795531" "unprognostic (2.76e-1)" "prognostic favorable (5.69e-5)" "unprognostic (1.17e-1)" "unprognostic (3.09e-3)" "unprognostic (1.69e-2)" "unprognostic (1.80e-3)" "prognostic unfavorable (2.77e-5)" "unprognostic (3.98e-1)" "unprognostic (1.16e-1)" "unprognostic (1.83e-1)" "unprognostic (3.44e-3)" "unprognostic (3.89e-1)" "unprognostic (2.18e-1)" "unprognostic (5.50e-2)" "unprognostic (3.68e-2)" "unprognostic (3.60e-3)" "unprognostic (1.03e-1)" 1.4 1.5 2.2 12.3 2.0 9.9 5.1 1.0 2.2 4.8 0.9 12.5 7.5 2.9 3.9 10.8 2.1 2.2 1.6 2.3 1.3 3.4 4.3 1.9 31.4 1.2 1.3 3.0 1.8 1.3 0.6 19.3 1.2 3.2 14.4 0.5 2.4 2.1 0.9 10.2 8.8 2.3 1.0 3.5 7.0 14.0 1.4 36.8 1.5 0.6 34.9 4.5 4.4 1.8 60.3 39.5 75.2 32.6 3.3 15.8 33.0 35.9 26.8 31.6 51.8 15.4 69.2 83.8 29.1 15.8 35.3 34.4 32.4 32.5 50.5 16.6 30.5 45.3 22.6 102.5 1.3 17.6 19.5 3.7 6.1 14.5 13.3 12.3 17.4 36.2 65.3 63.2 16.5 70.3 60.9 83.1 64.1 82.6 15.7 73.1 81.1 89.3 18.7 38.0 44.1 35.0 28.5 47.4 26.1 43.5 80.4 25.8 5.6 25.1 23.3 49.3 5.0 18.1 30.9 99.3 23.3 57.4 47.2 0.0 0.0 0.4 0.3 0.0 0.0 4.2 0.1 0.0 0.2 1.1 0.8 0.3 0.1 0.1 0.0 0.2 1.4 0.1 2.2 2.0 1.0 2.2 2.3 1.3 1.2 1.3 1.2 1.0 1.4 1.8 1.3 0.0 0.5 0.0 4.5 6.8 5.4 1.4 6.2 0.2 3.4 3.2 1.0 4.3 1.6 7.3 0.0 123.8 0.5 3.3 5.9 2.6 3.0 0.8 2.1 2.8 2.4 38.5 0.0 0.5 34.1 6.4 4.1 2.2 0.0 19.7 1.1 1.1 18.5 0.0 0.0 7.7 0.0 0.8 6.5 5.9 15.8 3.7 3.6 0.0 1.1 0.2 1.0 0.0 0.0 1.0 4.0 42.5 2.4 2.1 1.3 0.4 0.1 0.6 32.9 0.0 2.2 36.6 51.8 11.3 5.4 47.7 1.9 6.5 10.3 7.5 RNF26 MGC2642 ENSG00000173456 "Ring finger protein 26" Q9BY78 11 119334527-119337309 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 66.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA027620 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 85: Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Vesicles, Cytosol" "HPA027620: AB_1856356" "unprognostic (9.23e-3)" "unprognostic (3.54e-2)" "unprognostic (1.36e-1)" "unprognostic (8.68e-3)" "unprognostic (3.40e-1)" "unprognostic (1.07e-2)" "prognostic unfavorable (3.19e-4)" "unprognostic (2.14e-2)" "unprognostic (3.26e-1)" "unprognostic (1.69e-1)" "unprognostic (7.24e-3)" "unprognostic (6.22e-2)" "prognostic favorable (3.45e-6)" "unprognostic (9.61e-2)" "unprognostic (3.50e-2)" "unprognostic (4.41e-2)" "prognostic unfavorable (7.73e-4)" 14.3 15.8 12.7 11.5 12.6 22.0 13.3 13.7 15.1 15.4 10.6 19.2 14.5 23.5 10.3 20.9 16.6 10.5 13.2 12.7 12.5 13.6 23.6 12.4 11.8 15.2 13.1 17.1 13.8 18.5 10.4 14.2 15.5 14.8 12.6 8.4 14.9 18.6 8.5 15.7 17.0 19.0 12.7 14.6 19.1 15.1 14.7 13.3 13.2 7.1 12.8 18.9 14.2 13.1 43.8 47.4 43.4 51.4 41.8 32.8 46.0 46.3 49.7 52.8 41.5 80.6 88.9 38.3 62.5 55.5 80.1 77.2 61.9 69.8 33.0 46.0 34.2 101.0 21.8 67.3 31.9 42.8 40.4 34.3 35.2 66.1 59.0 34.7 40.8 58.1 50.0 58.4 36.9 94.9 39.5 44.3 43.5 50.2 59.8 40.5 44.5 30.4 32.7 31.1 30.8 29.9 37.4 46.8 12.5 41.4 106.1 35.4 27.0 63.5 41.8 33.7 43.0 14.0 24.6 0.4 21.3 71.0 50.6 9.5 21.6 5.6 20.8 19.2 13.4 11.1 15.7 18.4 19.0 16.7 17.5 15.5 1.5 14.0 20.2 11.0 8.7 24.9 12.7 12.6 13.7 15.1 12.7 12.5 15.2 13.1 15.5 12.7 14.7 13.1 5.1 3.2 9.4 1.0 9.1 6.9 13.3 15.4 12.5 9.2 10.9 9.8 0.8 22.8 11.1 11.0 2.1 44.0 6.2 9.3 5.9 20.8 6.6 5.9 7.9 8.6 13.8 18.5 3.2 17.0 66.0 11.5 9.2 5.9 7.6 16.9 11.4 23.4 21.5 5.0 2.9 13.0 8.2 14.8 5.9 8.6 14.0 6.6 1.8 1.0 11.6 11.6 15.5 4.5 2.7 14.1 7.5 17.7 4.3 14.2 15.6 12.5 4.8 9.4 6.6 6.5 10.6 19.9 10.5 14.3 8.5 24.4 8.3 8.8 18.6 9.8 RPL36AL RPL36A ENSG00000165502 "Ribosomal protein L36a like" Q969Q0 14 49618530-49620626 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" HPA077586 Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "Plasma membrane" "HPA077586: AB_2686846" "unprognostic (1.55e-2)" "unprognostic (2.44e-2)" "unprognostic (8.73e-2)" "unprognostic (3.15e-3)" "unprognostic (1.52e-1)" "unprognostic (2.55e-2)" "unprognostic (1.31e-1)" "unprognostic (6.37e-2)" "unprognostic (4.18e-2)" "unprognostic (1.38e-3)" "unprognostic (2.29e-1)" "unprognostic (4.72e-1)" "unprognostic (1.16e-3)" "unprognostic (8.32e-2)" "unprognostic (2.80e-1)" "prognostic favorable (2.83e-4)" "unprognostic (1.00e-1)" 279.7 310.9 234.2 246.4 241.7 404.2 328.6 232.1 349.8 381.8 221.4 331.8 260.5 280.7 492.7 277.4 315.9 162.6 273.2 225.1 244.6 255.3 372.3 240.5 311.9 244.4 237.3 501.3 628.8 220.0 252.9 176.7 240.6 250.8 248.8 102.0 327.5 253.2 378.6 247.6 284.9 197.9 242.0 294.2 360.3 137.6 240.5 283.4 211.2 206.5 377.1 297.8 285.9 246.2 635.8 473.9 330.1 192.6 471.3 649.8 194.9 508.9 569.9 475.4 534.7 499.0 426.1 833.4 474.5 430.3 327.9 443.5 287.6 441.3 554.8 288.1 331.1 521.6 527.5 652.8 595.1 838.8 426.0 667.8 668.2 362.7 485.9 553.7 614.6 367.3 339.5 714.4 372.8 831.7 496.5 752.6 186.0 452.1 482.0 308.6 519.5 449.5 730.7 964.2 290.3 178.1 448.5 350.8 544.1 313.0 762.2 460.1 468.2 291.3 463.0 382.3 399.8 427.6 487.0 842.7 210.5 376.9 283.7 1308.9 603.0 935.1 823.8 582.2 1113.2 959.3 1070.1 1040.5 614.8 729.1 984.7 937.6 654.0 806.3 542.2 1008.3 1096.2 1506.1 234.2 241.7 232.1 349.8 225.1 244.6 244.4 237.3 240.6 242.0 240.5 246.2 453.2 307.7 395.4 11.4 666.4 945.7 1352.2 1151.7 422.3 110.9 674.6 1022.1 662.4 652.0 643.5 312.6 25.0 690.0 778.0 871.5 995.9 739.8 614.3 490.0 431.4 515.5 366.2 535.9 14.1 1371.2 720.9 523.6 381.3 543.7 716.4 369.2 591.8 920.1 778.5 80.8 16.0 793.7 520.8 814.1 1020.0 236.4 725.7 585.0 843.1 22.5 1045.3 368.1 930.0 11.6 22.9 1311.2 1063.8 534.1 853.2 1279.2 1151.2 1194.4 579.1 127.7 486.4 693.6 898.3 364.7 150.2 390.6 839.3 516.3 888.1 355.4 620.5 1412.3 RPS19BP1 "FLJ21770, MGC52010" ENSG00000187051 "Ribosomal protein S19 binding protein 1" Q86WX3 22 39529093-39532761 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042874 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Cytosol" Nucleoplasm "HPA042874: AB_10793988" "unprognostic (2.44e-1)" "unprognostic (1.67e-1)" "unprognostic (7.79e-2)" "unprognostic (5.07e-3)" "unprognostic (1.65e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (3.71e-4)" "unprognostic (1.65e-1)" "unprognostic (5.68e-2)" "unprognostic (8.31e-2)" "unprognostic (7.00e-2)" "unprognostic (6.73e-2)" "unprognostic (1.04e-1)" "unprognostic (6.11e-2)" "unprognostic (1.65e-1)" "unprognostic (2.34e-1)" "unprognostic (4.32e-2)" 98.5 123.0 122.2 43.1 124.5 61.7 94.6 126.7 159.0 73.5 115.9 117.1 43.5 65.5 31.5 94.2 65.6 19.3 114.6 121.2 119.7 123.1 158.5 80.4 48.0 126.5 124.2 68.9 109.6 47.1 66.5 30.2 123.7 108.1 19.2 23.9 94.4 42.8 104.7 80.0 78.3 19.7 124.8 100.5 101.5 65.8 128.4 40.5 96.7 45.4 34.6 99.9 73.7 123.9 94.8 117.6 54.5 80.4 60.7 39.7 110.8 102.0 87.3 92.5 74.0 131.1 62.1 118.9 107.4 64.5 74.8 73.8 87.8 111.3 32.2 163.8 261.5 110.0 105.5 118.0 88.2 166.8 142.3 60.1 83.1 80.3 96.8 49.4 64.9 87.6 128.0 83.8 61.0 108.0 80.6 164.1 95.1 210.9 209.5 127.3 70.0 182.0 99.7 95.8 121.2 66.9 85.8 137.3 203.1 33.6 98.8 134.8 74.0 77.5 168.8 85.7 141.7 140.3 145.4 188.4 103.3 116.8 183.1 126.8 147.4 187.3 133.0 141.6 123.5 159.7 135.1 140.6 122.4 173.9 129.9 132.8 168.7 128.9 119.4 193.1 165.1 138.3 122.2 124.5 126.7 159.0 121.2 119.7 126.5 124.2 123.7 124.8 128.4 123.9 113.6 44.8 51.4 13.1 109.5 137.1 94.3 124.3 84.2 98.0 178.6 205.7 73.8 105.8 83.0 97.5 52.1 152.9 114.7 205.5 217.2 174.9 23.6 68.6 69.8 121.0 142.6 83.5 8.7 192.2 231.9 92.0 76.0 81.6 69.8 62.0 116.0 184.8 204.3 35.3 10.9 207.5 130.2 116.4 233.3 40.3 137.0 110.8 108.5 8.4 147.8 139.1 162.7 5.5 18.7 233.5 202.2 126.0 193.3 206.8 274.9 362.2 54.0 103.7 78.9 74.4 100.9 61.6 138.0 87.6 147.9 131.6 115.2 103.1 165.9 132.4 RPS27A "S27A, Uba80, UBCEP80" ENSG00000143947 "Ribosomal protein S27a" P62979 2 55231903-55235853 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033319, HPA041344, HPA049132, HPA054087" Supported Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA Yes 230000000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Nucleoli, Endoplasmic reticulum, Cytosol" "CAB033319: AB_793618, HPA041344: AB_2677422, HPA049132: AB_2680646, HPA054087: AB_2682373" "unprognostic (7.32e-2)" "unprognostic (1.41e-2)" "unprognostic (1.11e-1)" "unprognostic (3.20e-3)" "unprognostic (2.16e-1)" "unprognostic (9.75e-2)" "prognostic unfavorable (2.26e-4)" "unprognostic (1.39e-1)" "unprognostic (1.65e-2)" "unprognostic (2.46e-1)" "unprognostic (6.89e-2)" "unprognostic (1.70e-1)" "prognostic unfavorable (2.60e-6)" "unprognostic (1.09e-1)" "unprognostic (8.82e-2)" "unprognostic (1.47e-1)" "unprognostic (3.60e-1)" 1440.7 1208.5 1115.0 1077.7 1151.0 2567.0 2511.6 1098.2 1883.7 2166.1 1099.2 1563.5 823.5 1450.9 1105.1 1698.4 1726.7 572.2 943.7 1085.1 1131.6 1254.8 1162.3 1097.1 1955.6 1133.6 1117.0 3146.7 2043.5 730.2 1057.5 872.9 1131.4 1430.2 1045.0 631.9 1387.4 917.9 1089.6 1767.3 1328.6 814.7 1172.6 1719.2 1478.2 405.9 1150.4 1520.4 1201.6 793.7 1774.4 1506.3 1694.7 1157.1 2384.4 1092.2 1412.2 1842.3 1892.6 3200.3 2412.6 1824.5 1779.4 1692.3 1069.1 2073.7 1987.4 3081.3 2833.2 1698.5 1115.0 1784.3 2061.7 2465.1 1981.0 2899.1 2419.0 2693.9 1088.0 2758.1 2705.9 3674.4 1605.2 3166.1 4213.4 1280.5 3401.6 3015.5 2415.9 1959.5 2469.0 2228.9 1937.3 1509.9 2307.6 4328.7 2831.1 2690.2 1710.6 2086.4 3051.2 3173.8 1994.3 1817.4 1546.0 1319.2 1064.4 4071.8 3843.7 2065.9 1811.0 3411.1 2108.9 1351.7 2395.8 1318.7 3006.7 2322.2 1881.5 1867.9 1923.5 3226.7 1392.6 1301.5 1656.9 637.7 2924.2 1530.8 4268.2 4727.8 4504.3 3592.2 2219.0 4232.8 5675.0 4744.3 351.6 3178.7 1388.8 3292.5 3058.2 8225.2 1115.0 1151.0 1098.2 1883.7 1085.1 1131.6 1133.6 1117.0 1131.4 1172.6 1150.4 1157.1 3051.9 1272.4 2321.3 39.8 7158.8 8321.0 8963.0 6850.9 5010.5 446.4 8189.8 10987.6 438.8 3029.7 3486.3 1397.8 214.8 5340.9 5465.1 1499.3 4055.8 3640.9 1050.2 1695.4 3081.0 3385.0 2057.4 3362.1 45.8 7348.0 6754.1 3043.5 1762.0 1917.3 3014.6 3565.0 3729.5 3181.0 3498.7 218.7 47.8 3995.4 2199.2 5051.0 6045.7 1576.9 5081.5 3382.7 3639.2 59.0 6346.8 2229.4 5579.8 29.1 61.0 5045.3 3396.0 2881.2 3458.4 8189.2 3670.3 5961.1 1726.4 760.9 1643.5 5220.3 4020.2 1047.7 863.4 5750.5 8931.2 5390.3 6365.7 3721.9 4717.6 7980.9 RPS7 "eS7, S7" ENSG00000171863 "Ribosomal protein S7" P62081 2 3575260-3580920 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056586 Approved Approved "Endoplasmic reticulum,Cytosol" NA Yes 820000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "HPA056586: AB_2683179" "unprognostic (3.28e-3)" "unprognostic (1.85e-1)" "unprognostic (7.07e-2)" "unprognostic (2.29e-1)" "unprognostic (3.00e-2)" "unprognostic (5.20e-2)" "prognostic unfavorable (5.27e-4)" "unprognostic (6.41e-2)" "unprognostic (6.02e-3)" "unprognostic (7.08e-2)" "unprognostic (5.60e-2)" "unprognostic (6.27e-2)" "prognostic unfavorable (1.34e-8)" "unprognostic (3.70e-2)" "unprognostic (2.48e-2)" "unprognostic (1.68e-1)" "unprognostic (1.55e-1)" 1083.4 764.7 778.0 774.7 787.2 2152.4 2194.5 772.7 1112.6 1124.8 800.2 1044.1 766.0 867.6 1309.0 1281.8 1152.1 642.5 744.5 755.7 779.1 925.4 1082.6 717.6 1622.5 785.1 770.8 2394.6 1624.1 725.0 686.2 939.7 784.8 887.8 1166.3 603.2 1213.7 697.3 906.5 1419.8 866.8 895.3 805.3 964.6 1011.3 396.3 795.7 1665.6 797.7 843.0 1841.7 1038.2 1063.0 798.4 1235.6 1178.5 1778.9 1923.5 1725.8 3754.0 2913.5 1458.3 2527.9 2370.8 1371.5 2053.4 1890.4 4081.0 2369.1 1697.7 1646.1 1321.0 2038.5 2370.0 2077.4 1289.4 2743.3 1496.8 758.2 2998.2 4156.0 2622.8 1489.1 3183.4 3497.5 1475.1 3176.3 2552.1 2816.8 3707.9 2356.3 2015.2 2433.4 1661.0 2930.2 5815.8 2638.6 3679.7 1810.5 2300.9 1812.6 3670.5 2725.7 1487.1 2016.6 3028.5 771.7 2931.1 4670.0 1487.2 1615.3 3727.3 1327.2 1415.1 931.1 987.9 2387.5 2240.1 4420.9 4079.3 1489.6 3113.0 1617.9 337.1 656.8 243.1 808.8 570.7 1192.3 1411.3 1159.2 1036.9 1063.6 1172.7 1254.6 1132.2 129.3 1032.8 553.2 1016.6 1083.5 2065.3 778.0 787.2 772.7 1112.6 755.7 779.1 785.1 770.8 784.8 805.3 795.7 798.4 2544.8 496.8 793.2 28.1 3845.5 3923.3 4252.7 2961.9 3989.5 401.5 4245.2 7977.4 154.5 1720.0 1620.6 647.4 325.2 3627.9 2815.0 730.8 2606.1 2129.9 1517.5 1255.0 3316.9 1997.7 1250.9 2352.4 33.5 3434.0 5702.2 1854.2 1378.2 1489.1 1171.5 2855.2 2067.5 1515.6 2338.1 141.3 37.2 2244.0 929.8 2534.9 3126.0 485.1 2927.6 2110.0 2001.1 50.6 3250.8 1257.2 2634.4 27.6 49.8 2878.9 1747.3 1748.6 2572.7 4420.1 1233.7 4372.3 847.1 741.6 1452.9 1699.5 3261.7 1248.6 775.4 4912.8 5050.7 3716.9 3078.6 3673.3 2604.1 4351.5 RPS9 S9 ENSG00000170889 "Ribosomal protein S9" P46781 19 54200809-54249003 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048746 Approved NA Yes 64000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "HPA048746: AB_2680510" "prognostic favorable (9.23e-4)" "unprognostic (1.11e-1)" "unprognostic (4.84e-2)" "unprognostic (1.15e-3)" "unprognostic (1.22e-2)" "unprognostic (2.82e-1)" "unprognostic (4.61e-2)" "unprognostic (3.12e-1)" "unprognostic (2.58e-1)" "unprognostic (2.09e-1)" "unprognostic (1.04e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.63e-4)" "unprognostic (2.22e-1)" "unprognostic (9.45e-2)" "unprognostic (5.08e-2)" "unprognostic (3.14e-2)" 1846.1 1581.0 641.4 518.8 641.4 1359.3 1991.4 639.9 975.3 2001.5 638.1 1524.9 564.9 1523.5 469.1 2126.8 1633.0 302.8 1353.2 643.2 640.4 1437.6 1647.5 1359.5 682.3 654.2 658.1 3458.6 3439.2 314.2 932.7 325.4 645.0 1662.3 355.4 79.1 1512.6 167.0 1680.6 2686.6 1454.5 368.3 640.7 1812.7 1610.9 455.4 649.9 968.4 1272.0 627.6 652.3 1582.5 1861.8 647.6 500.8 204.0 257.8 695.7 1424.1 1563.5 602.5 440.1 254.9 246.2 124.4 216.2 861.6 899.9 518.5 785.5 398.8 677.4 922.7 1119.2 196.3 505.5 310.3 328.7 42.2 221.0 1293.3 708.5 711.7 2154.8 1199.7 686.8 882.1 838.6 861.4 831.0 452.2 978.5 693.8 148.0 1452.1 2013.6 770.5 636.4 200.7 865.5 406.3 1507.6 1201.0 228.9 532.3 926.3 255.6 749.5 1308.2 304.6 1003.0 2054.0 249.1 425.4 652.4 545.4 725.2 748.9 663.0 773.2 638.7 752.2 525.7 178.8 847.5 163.1 533.1 712.2 877.4 1075.6 917.4 673.0 741.2 1129.0 1237.5 1060.6 534.1 658.8 677.2 1018.9 627.1 2882.7 641.4 641.4 639.9 975.3 643.2 640.4 654.2 658.1 645.0 640.7 649.9 647.6 1501.4 458.3 1166.6 22.2 3076.3 6471.6 6044.0 4452.4 2423.9 346.2 6390.8 6524.1 198.1 1996.0 1877.7 886.5 175.2 2267.8 2511.4 1539.2 2488.7 1954.7 794.3 1011.6 2061.6 2294.9 1974.5 1549.2 13.6 5626.0 4374.8 1874.4 911.8 1416.2 838.2 2875.5 2494.0 2045.6 2693.9 175.0 14.6 3345.8 1377.3 3888.3 5294.3 1889.2 2872.7 2675.0 3283.5 25.3 3499.1 1219.7 2250.3 16.6 45.8 2925.9 2828.6 1518.0 1474.4 5077.4 3010.2 3183.8 786.3 682.9 1051.8 3030.1 2744.3 526.5 484.2 2627.6 7500.0 2470.4 2489.3 2886.3 3908.4 5842.9 RUSC1 NESCA ENSG00000160753 "RUN and SH3 domain containing 1" Q9BVN2 1 155320894-155331114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 82.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028510, HPA029922, HPA029923" Approved Enhanced Cytosol NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA028510: AB_10599847, HPA029922: AB_10611390, HPA029923: AB_10602288" "unprognostic (1.98e-1)" "unprognostic (2.82e-1)" "unprognostic (2.36e-1)" "unprognostic (1.50e-1)" "unprognostic (5.25e-2)" "unprognostic (2.52e-1)" "prognostic unfavorable (7.78e-6)" "unprognostic (1.42e-1)" "unprognostic (1.38e-1)" "unprognostic (1.73e-1)" "unprognostic (8.29e-2)" "prognostic unfavorable (2.65e-4)" "prognostic unfavorable (9.24e-6)" "unprognostic (7.59e-2)" "unprognostic (4.25e-2)" "unprognostic (2.05e-2)" "unprognostic (1.40e-1)" 27.0 26.6 42.0 11.6 40.7 12.8 23.2 39.9 66.0 38.0 11.3 39.2 21.6 28.8 8.7 49.5 24.8 16.8 28.8 38.9 41.1 32.1 12.6 23.7 10.7 55.2 34.0 27.5 22.5 11.7 45.0 18.2 53.2 32.1 22.9 11.9 32.0 20.3 14.1 37.3 29.9 18.6 28.3 18.0 27.3 6.6 41.4 18.6 19.3 13.3 11.3 26.6 39.2 41.0 70.4 43.5 24.5 36.4 29.6 32.1 47.2 32.7 20.8 42.2 47.1 50.1 45.2 13.7 24.4 33.2 24.2 95.1 38.3 47.4 18.2 18.8 48.8 19.8 44.7 26.6 24.5 19.9 32.9 33.0 29.3 42.5 14.6 20.4 43.9 29.7 30.5 9.4 36.9 133.4 25.0 25.3 48.4 128.4 68.3 33.6 17.1 24.3 40.3 52.7 25.2 40.5 27.6 76.9 16.8 39.8 114.8 33.6 20.2 54.0 44.4 51.4 65.8 7.4 18.0 8.6 38.2 26.5 15.0 5.8 8.0 4.0 6.3 9.8 7.2 3.6 5.1 6.4 8.8 1.5 2.8 6.0 1.1 3.3 25.2 8.4 5.5 5.4 42.0 40.7 39.9 66.0 38.9 41.1 55.2 34.0 53.2 28.3 41.4 41.0 18.2 9.6 12.7 4.9 8.0 28.0 20.1 29.5 22.8 16.9 21.3 19.3 10.2 15.7 27.9 18.4 6.2 30.8 14.8 82.2 23.5 22.4 0.4 9.9 14.7 20.0 15.6 14.5 23.8 17.7 76.6 19.1 25.5 23.6 8.2 9.8 16.4 7.8 21.0 37.0 30.5 51.7 18.3 12.8 20.3 0.5 18.3 11.9 19.6 6.5 11.7 13.4 15.5 7.1 8.2 25.6 43.7 18.0 8.4 29.4 51.8 27.9 10.4 7.0 19.7 12.7 22.2 2.3 8.9 41.4 34.9 38.0 15.2 6.7 40.1 26.0 SAPCD2 "C9orf140, p42.3" ENSG00000186193 "Suppressor APC domain containing 2" Q86UD0 9 137062127-137070557 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.1;esophagus: 8.5;skin 1: 6.2" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 10.8;Oligodendrocyte precursor cells: 29.7;Undifferentiated cells: 12.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 122.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA044154 Approved Supported Nucleoplasm,Nucleoli,Cytosol NA Yes "Cluster 27: Brain & Skin - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Nucleoplasm, Nucleoli" "HPA044154: AB_10959464" "unprognostic (3.68e-2)" "unprognostic (9.85e-2)" "unprognostic (1.13e-1)" "unprognostic (1.11e-1)" "unprognostic (2.80e-2)" "unprognostic (1.27e-1)" "unprognostic (5.42e-8)" "prognostic unfavorable (5.88e-4)" "unprognostic (8.33e-2)" "unprognostic (7.47e-2)" "unprognostic (1.22e-2)" "unprognostic (1.45e-1)" "unprognostic (9.83e-7)" "unprognostic (4.37e-3)" "unprognostic (4.62e-1)" "unprognostic (3.82e-2)" "unprognostic (1.35e-2)" 0.5 0.3 6.9 2.4 5.1 2.0 1.3 4.7 5.4 1.2 1.3 3.7 4.3 0.4 0.0 8.5 0.3 0.2 0.2 5.4 4.5 1.2 0.2 0.5 2.7 7.1 6.8 0.1 0.4 0.0 0.5 0.9 5.7 3.1 1.8 0.1 4.1 0.1 0.1 6.2 4.3 0.4 5.0 2.2 2.4 0.5 6.8 2.3 0.3 0.0 2.5 0.4 2.3 7.0 52.1 27.5 10.7 32.0 0.3 0.7 57.1 8.4 5.7 8.8 4.1 52.5 23.2 53.8 26.5 4.1 8.2 72.3 33.6 9.7 2.0 37.4 38.9 23.6 32.7 59.6 0.2 27.0 39.2 0.1 1.5 3.0 5.8 2.3 14.4 27.1 33.1 23.7 2.6 122.1 7.8 72.7 19.9 119.2 61.9 82.9 40.7 60.1 10.9 14.8 55.2 32.7 32.2 89.1 12.2 2.4 71.9 51.1 9.4 7.9 26.6 24.0 41.9 8.2 25.5 26.3 18.4 31.8 25.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.9 5.1 4.7 5.4 5.4 4.5 7.1 6.8 5.7 5.0 6.8 7.0 0.5 0.0 0.0 0.7 1.9 4.2 0.7 0.5 0.6 0.2 5.0 5.2 1.3 0.0 1.1 0.0 0.0 2.8 1.6 5.4 1.9 0.3 0.0 1.6 0.8 0.9 0.0 3.6 0.2 0.0 3.5 1.1 6.1 6.0 0.0 3.3 1.4 0.0 3.1 0.0 0.2 10.8 0.0 2.8 1.5 0.1 0.0 2.2 0.0 0.0 1.5 0.5 0.0 29.7 5.6 0.6 4.0 0.0 1.8 2.1 0.5 0.0 0.1 0.6 0.0 0.2 1.0 0.0 1.4 5.8 2.7 0.5 1.3 0.6 12.1 1.1 SCD "FADS5, SCDOS" ENSG00000099194 "Stearoyl-CoA desaturase" O00767 10 100347233-100364826 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 1233.7;brain: 839.9;liver: 583.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 389.6;Granulosa cells: 187.3;Hepatocytes: 840.3;Oligodendrocytes: 451.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "ASC diff: 2534.2;CAPAN-2: 1824.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012107, HPA063921" Approved Enhanced "Endoplasmic reticulum" No Yes "Cluster 7: Monocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "HPA012107: AB_1856610, HPA063921: AB_2685154" "unprognostic (2.10e-1)" "unprognostic (2.62e-3)" "unprognostic (7.86e-2)" "unprognostic (5.19e-2)" "unprognostic (1.24e-1)" "unprognostic (6.16e-2)" "unprognostic (1.13e-1)" "unprognostic (3.88e-2)" "unprognostic (6.53e-2)" "unprognostic (2.72e-1)" "unprognostic (1.47e-1)" "unprognostic (1.69e-1)" "prognostic unfavorable (7.56e-5)" "unprognostic (7.18e-2)" "unprognostic (3.27e-1)" "unprognostic (4.73e-2)" "prognostic unfavorable (7.79e-5)" 1233.7 131.2 408.7 25.7 525.8 23.0 261.5 535.7 522.1 43.2 156.6 42.9 93.1 15.4 25.5 107.8 5.0 28.7 47.1 349.1 457.5 18.5 583.8 142.8 17.2 775.0 508.9 49.6 22.6 79.5 10.3 19.9 637.8 100.1 39.7 17.9 112.6 11.2 6.1 27.0 36.0 15.9 574.4 15.3 25.2 51.8 538.7 18.4 13.0 7.2 21.0 22.5 41.9 839.9 411.2 373.3 777.6 536.4 2534.2 1449.4 158.2 43.4 948.3 101.6 536.6 323.8 1824.4 173.3 33.7 102.2 461.8 716.4 433.7 1549.5 88.9 59.4 179.6 97.5 219.3 653.4 488.4 136.9 100.9 795.5 459.4 395.0 688.9 273.1 196.2 375.3 275.4 513.3 41.7 646.8 155.9 163.3 270.7 120.7 106.3 72.6 287.4 550.4 443.8 455.3 48.9 185.3 85.8 399.7 834.9 224.2 447.7 291.3 79.0 10.0 115.9 9.1 89.8 141.4 81.5 262.9 184.4 416.0 65.9 0.0 0.8 0.0 1.4 1.6 2.3 0.6 0.5 0.7 2.7 0.9 0.4 1.3 0.1 1.4 0.0 1.5 0.0 1.2 408.7 525.8 535.7 522.1 349.1 457.5 775.0 508.9 637.8 574.4 538.7 839.9 3.8 54.5 389.6 34.0 15.7 3.7 4.5 121.8 0.6 6.5 16.1 6.2 11.2 28.6 66.2 0.0 6.2 3.0 4.7 21.5 0.0 14.6 52.6 13.9 9.0 12.5 25.8 15.8 4.8 67.9 71.7 15.9 25.0 26.9 6.3 187.3 32.9 840.3 34.1 26.9 5.2 16.4 52.9 113.5 4.2 93.0 3.7 21.2 58.7 8.4 10.2 11.9 2.1 18.6 451.5 29.6 2.7 1.5 3.7 31.4 16.2 4.9 31.0 6.2 0.0 3.6 25.7 2.0 1.2 26.7 2.3 17.4 6.6 97.8 38.9 8.2 SCLT1 "FLJ30655, hCAP-1A" ENSG00000151466 "Sodium channel and clathrin linker 1" Q96NL6 4 128864921-129093600 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Astrocytes: 110.0;Excitatory neurons: 111.1;Inhibitory neurons: 116.0;Oligodendrocyte precursor cells: 109.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 66.0" "Group enriched" "Detected in all" 5 "granulocytes: 66.0;monocytes: 31.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036560, HPA036561" Approved Uncertain Microtubules,Cytosol NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Microtubules, Cytosol" "HPA036560: AB_2675190, HPA036561: AB_10673658" "unprognostic (2.15e-1)" "unprognostic (2.01e-1)" "unprognostic (1.62e-2)" "unprognostic (3.77e-2)" "unprognostic (5.05e-2)" "unprognostic (9.18e-2)" "unprognostic (1.33e-3)" "unprognostic (1.64e-2)" "unprognostic (1.94e-2)" "unprognostic (4.99e-2)" "unprognostic (3.86e-1)" "unprognostic (3.09e-2)" "unprognostic (5.34e-4)" "unprognostic (6.54e-2)" "unprognostic (2.70e-1)" "unprognostic (6.05e-2)" "unprognostic (8.92e-2)" 3.6 3.0 3.7 6.4 4.5 14.4 3.5 7.4 4.8 3.7 0.9 3.7 4.3 3.5 2.2 3.9 3.1 4.6 3.6 2.4 2.8 2.7 3.5 3.5 7.3 4.5 4.3 4.5 3.3 2.9 2.9 4.6 3.5 2.4 4.4 2.9 2.6 2.7 1.5 3.2 3.4 3.6 4.7 7.5 3.5 4.9 5.3 8.8 3.0 1.8 6.7 4.4 3.4 3.9 19.9 5.3 18.8 12.4 6.5 10.5 10.3 16.5 14.8 17.8 16.3 5.7 17.1 17.0 10.4 9.3 12.4 7.4 12.5 12.2 18.5 38.9 10.0 22.7 10.2 6.5 8.9 27.1 17.0 6.7 4.3 14.2 14.2 8.5 14.0 8.6 25.7 39.8 15.6 8.8 20.8 13.0 8.4 14.2 10.5 12.2 19.2 10.6 11.4 5.5 28.1 8.2 12.7 11.5 11.1 8.2 6.8 10.8 13.2 14.5 17.6 19.7 22.3 19.3 15.5 29.0 8.1 29.7 22.2 18.3 16.9 36.8 3.8 24.6 2.2 3.9 2.6 2.7 9.5 3.7 2.5 3.4 66.0 10.2 31.1 4.4 3.7 6.5 3.7 4.5 7.4 4.8 2.4 2.8 4.5 4.3 3.5 4.7 5.3 3.9 16.1 12.8 9.8 110.0 18.0 11.1 8.9 5.8 8.0 15.2 6.1 7.4 21.2 15.7 9.0 1.8 29.2 13.8 34.8 9.1 3.9 6.5 63.2 20.3 18.4 11.9 5.4 9.0 111.1 6.3 21.5 16.3 28.1 14.3 12.0 16.5 9.3 1.6 13.3 16.8 116.0 8.1 8.2 21.6 18.0 51.8 10.8 28.4 8.8 87.1 33.8 8.9 82.4 109.1 90.5 9.0 9.8 9.1 24.0 2.7 8.2 3.1 16.7 21.6 13.1 14.4 16.5 19.6 12.1 13.1 13.9 9.3 21.2 30.5 10.6 5.6 SERF2 "4F5REL, FAM2C, H4F5rel, HsT17089" ENSG00000140264 "Small EDRK-rich factor 2" P84101 15 43777087-43804427 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056613 Uncertain Nucleoplasm,Nucleoli NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Nucleoli "HPA056613: " "unprognostic (3.29e-1)" "unprognostic (7.29e-2)" "unprognostic (1.13e-3)" "prognostic favorable (5.33e-4)" "unprognostic (1.40e-1)" "unprognostic (3.91e-2)" "unprognostic (6.06e-2)" "unprognostic (1.61e-1)" "unprognostic (1.13e-1)" "unprognostic (2.50e-1)" "unprognostic (3.04e-1)" "unprognostic (1.36e-1)" "unprognostic (3.37e-2)" "unprognostic (2.84e-1)" "unprognostic (3.35e-2)" "unprognostic (2.76e-2)" "unprognostic (9.42e-2)" 760.6 1067.4 704.4 446.7 726.4 944.9 619.4 750.2 906.3 650.8 1027.1 728.4 443.4 509.9 776.2 887.9 456.8 469.4 1187.9 698.1 712.2 1002.2 1328.7 700.8 686.4 737.1 725.3 474.3 795.1 490.9 569.3 484.2 734.7 794.5 631.9 72.8 823.7 312.8 636.9 631.1 593.2 507.4 739.4 745.3 784.3 400.2 759.4 450.7 706.6 723.6 628.9 595.0 634.1 758.8 497.5 770.8 573.8 792.9 1963.2 1431.3 438.9 844.8 1042.5 540.4 682.7 991.5 470.0 250.4 694.7 1429.2 698.7 641.1 454.6 623.8 271.1 699.6 526.2 610.9 1074.9 1936.8 934.7 581.8 1235.8 1349.9 810.5 425.8 452.1 836.1 783.5 680.7 630.2 1593.5 1067.4 1441.8 758.6 1337.2 501.5 1849.7 885.1 743.9 382.6 1147.2 1462.5 1695.7 450.6 481.1 458.9 1871.5 463.9 488.4 1574.7 2363.9 682.9 920.0 469.0 1409.4 669.3 593.3 886.2 1837.8 989.2 1032.8 980.4 4033.8 5391.9 5884.9 2716.6 5055.2 2481.3 3853.8 2938.5 2784.5 4649.4 3901.8 2713.3 2731.7 3154.6 2568.8 4495.9 6486.5 3793.5 12856.7 704.4 726.4 750.2 906.3 698.1 712.2 737.1 725.3 734.7 739.4 759.4 758.8 1269.2 506.4 789.0 0.0 1149.8 1151.3 1379.1 3393.0 861.6 53.9 2373.1 2483.2 2229.8 1338.2 2099.5 1736.1 54.2 2660.9 1475.6 2388.2 3897.3 1707.6 576.8 1243.6 1343.1 1283.3 1167.5 1310.8 0.5 2255.2 3410.2 1489.3 1403.7 1261.0 785.9 775.2 1532.4 2884.5 3545.2 47.1 0.5 2862.6 2278.6 2262.1 2298.5 319.2 1225.3 2102.8 1817.8 0.0 2626.4 544.5 1881.6 1.5 0.3 1804.7 2363.9 992.2 1546.7 2188.9 3013.2 5083.6 1950.6 148.4 604.8 680.1 1737.3 750.2 381.1 1725.5 1556.5 3275.8 1216.9 1446.6 2042.5 2819.5 SERPINH1 "CBP1, CBP2, colligen, HSP47, SERPINH2" ENSG00000149257 "Serpin family H member 1" P50454 11 75562056-75572783 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Stress response" Chaperone "Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 473.6;Endometrial stromal cells: 273.3;Extravillous trophoblasts: 342.1;Fibroblasts: 287.6;Smooth muscle cells: 295.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebral cortex: 291.0" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 1018.3;fHDF/TERT166: 1215.2;HHSteC: 1029.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004441, HPA029198" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA Yes 920000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB004441: AB_627757, HPA029198: AB_10601712" "unprognostic (3.80e-1)" "prognostic unfavorable (2.10e-4)" "unprognostic (5.93e-2)" "unprognostic (2.81e-3)" "unprognostic (3.25e-2)" "prognostic unfavorable (1.85e-4)" "unprognostic (2.39e-2)" "unprognostic (1.72e-3)" "unprognostic (2.35e-2)" "unprognostic (7.40e-2)" "unprognostic (1.57e-2)" "unprognostic (2.54e-2)" "prognostic unfavorable (3.22e-15)" "unprognostic (2.75e-2)" "unprognostic (1.27e-1)" "unprognostic (3.93e-2)" "unprognostic (1.96e-2)" 214.1 101.9 46.2 106.5 50.4 3.7 107.1 51.1 291.0 137.7 66.7 95.2 23.2 160.7 27.6 41.7 119.4 72.1 159.3 46.1 50.5 116.9 52.5 199.3 21.1 59.9 47.3 157.4 40.1 18.1 50.8 251.3 58.3 66.1 36.7 2.0 40.7 53.2 22.2 47.6 51.3 207.3 51.6 53.9 76.9 27.7 54.0 21.6 91.2 33.2 18.2 156.8 85.9 60.1 57.7 192.9 349.5 722.0 528.8 484.2 162.2 514.3 349.6 380.4 483.5 1018.3 294.1 0.4 470.2 1215.2 3.1 337.2 242.2 163.2 182.5 27.5 47.0 42.7 174.0 216.5 1029.5 0.9 7.2 580.9 165.2 365.0 121.3 475.5 530.8 22.1 90.5 16.1 182.5 457.6 1.2 74.8 315.6 215.8 50.7 29.3 200.3 48.8 95.6 107.8 9.1 119.1 326.9 59.7 102.0 539.6 144.4 72.7 284.6 388.6 324.6 270.6 128.3 23.1 25.5 6.1 168.0 0.2 535.6 4.1 1.1 0.1 6.0 1.1 5.2 0.9 3.9 4.0 4.4 0.7 4.0 3.3 0.2 5.9 0.1 3.7 3.5 2.1 46.2 50.4 51.1 291.0 46.1 50.5 59.9 47.3 58.3 51.6 54.0 60.1 142.3 38.5 32.0 4.9 2.9 81.8 473.6 56.5 74.0 5.3 28.3 39.5 36.6 14.3 21.0 25.8 58.4 217.0 3.2 33.0 0.0 64.5 2.9 21.8 273.3 194.9 61.1 11.4 0.4 11.9 342.1 287.6 15.3 33.0 9.5 144.1 124.9 9.9 94.2 6.7 0.2 55.7 22.4 5.7 110.0 6.0 164.4 43.6 44.4 18.7 9.8 14.3 8.2 1.0 0.5 22.5 24.3 120.7 6.5 139.8 12.4 22.8 11.9 1.2 92.1 31.4 295.1 29.3 23.0 14.1 44.5 165.8 68.8 79.8 62.8 73.4 SERTAD3 RBT1 ENSG00000167565 "SERTA domain containing 3" Q9UJW9 19 40440844-40444335 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 187.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068262 Approved Nucleoli NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoli "HPA068262: AB_2685965" "unprognostic (1.56e-2)" "unprognostic (3.57e-2)" "unprognostic (1.10e-1)" "unprognostic (6.55e-3)" "unprognostic (6.50e-2)" "unprognostic (6.74e-2)" "unprognostic (2.24e-2)" "unprognostic (3.51e-3)" "unprognostic (7.18e-2)" "unprognostic (1.25e-1)" "unprognostic (1.28e-3)" "unprognostic (2.80e-2)" "unprognostic (8.74e-3)" "unprognostic (2.34e-1)" "unprognostic (2.88e-1)" "unprognostic (1.18e-1)" "unprognostic (4.66e-3)" 31.9 21.5 10.9 18.7 12.5 22.7 23.3 12.1 11.8 19.9 12.3 29.8 21.5 22.5 26.6 25.9 24.8 25.5 27.9 10.7 12.3 21.2 17.3 24.0 21.8 14.1 12.6 25.8 14.9 22.4 17.7 31.4 13.0 29.1 22.9 2.5 18.0 27.0 27.5 19.4 19.8 27.4 12.4 24.8 24.4 16.1 12.3 16.0 24.8 37.1 16.2 26.1 24.5 14.2 36.6 65.3 22.4 30.4 25.7 38.4 32.6 28.3 38.8 39.7 34.3 24.9 27.2 16.6 12.6 37.9 23.9 12.6 23.0 28.3 21.7 19.2 10.7 11.4 21.5 21.3 31.4 3.2 34.7 35.7 37.3 24.6 17.9 31.7 33.3 8.0 34.6 11.9 32.0 55.4 7.1 14.2 12.7 30.8 17.5 10.1 15.1 14.6 31.4 27.6 3.6 15.1 25.6 42.1 22.9 33.7 37.3 30.6 28.7 34.2 27.7 27.4 23.2 19.0 10.5 14.7 27.5 12.7 15.6 44.8 59.0 66.1 18.5 59.2 19.0 39.9 20.4 20.5 64.7 36.6 14.8 17.7 80.3 22.5 51.7 69.8 17.6 40.0 10.9 12.5 12.1 11.8 10.7 12.3 14.1 12.6 13.0 12.4 12.3 14.2 78.4 9.6 12.0 2.9 42.0 46.1 55.8 139.9 91.6 4.6 81.5 50.9 10.5 11.5 45.4 23.9 4.2 89.8 44.2 40.7 31.3 32.1 11.4 26.0 24.8 42.1 49.1 3.0 0.3 30.5 105.4 38.9 27.5 30.7 21.0 13.2 33.9 6.6 35.0 3.3 0.5 50.8 42.7 27.0 55.3 6.9 28.6 32.1 33.8 8.4 29.1 19.3 4.1 1.5 3.7 37.1 48.5 30.5 16.3 50.5 47.8 22.7 28.0 0.8 59.2 20.2 50.4 15.7 20.0 64.2 43.0 187.4 33.6 17.6 30.6 49.8 SESTD1 "DKFZp434O0515, Solo" ENSG00000187231 "SEC14 and spectrin domain containing 1" Q86VW0 2 179101678-179264832 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 175.5;Horizontal cells: 301.2;Oligodendrocytes: 311.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 45.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058236, HPA077408" Approved Enhanced "Intermediate filaments" NA Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" "Intermediate filaments" "HPA058236: AB_2732619, HPA077408: AB_2732344" "unprognostic (2.76e-1)" "unprognostic (3.55e-2)" "unprognostic (2.77e-1)" "unprognostic (2.12e-1)" "unprognostic (1.78e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.88e-4)" "unprognostic (9.47e-2)" "unprognostic (1.64e-1)" "unprognostic (2.59e-1)" "unprognostic (7.91e-3)" "unprognostic (9.21e-2)" "prognostic favorable (2.78e-11)" "prognostic unfavorable (2.67e-4)" "unprognostic (3.25e-2)" "unprognostic (1.25e-1)" "unprognostic (2.57e-2)" 15.4 2.4 11.6 3.2 17.2 4.7 11.2 12.5 11.4 6.2 0.9 7.1 2.0 5.8 3.9 4.5 4.5 6.4 6.3 8.2 10.3 6.7 3.4 9.2 3.4 16.2 13.5 4.5 3.3 3.9 3.6 6.8 14.6 4.2 3.8 7.5 11.0 4.6 3.6 4.5 5.4 8.1 15.1 3.5 5.5 9.0 18.1 2.9 3.7 5.8 4.9 10.0 4.8 23.6 0.0 2.1 25.5 4.6 45.2 19.5 13.5 9.0 3.7 3.7 6.3 4.6 6.0 4.5 11.7 8.7 4.5 4.2 11.0 5.1 6.8 3.3 2.9 5.5 11.2 12.3 3.5 3.1 2.3 14.6 2.1 5.7 14.3 8.9 15.2 4.6 0.8 2.3 6.4 3.1 7.2 0.3 6.6 4.7 2.6 10.3 16.8 2.9 10.0 23.2 5.6 9.5 8.0 3.4 2.5 18.7 0.5 3.4 26.7 12.3 6.2 6.3 4.7 1.3 0.0 11.0 6.2 1.2 3.7 0.0 0.9 0.0 0.0 0.7 0.0 1.2 0.0 0.0 0.4 1.5 0.0 0.0 0.1 0.3 1.6 0.0 0.0 0.2 11.6 17.2 12.5 11.4 8.2 10.3 16.2 13.5 14.6 15.1 18.1 23.6 46.2 109.0 29.9 53.2 30.6 9.8 24.7 19.1 7.4 31.3 30.4 15.6 15.3 28.6 32.9 12.9 18.8 10.7 5.7 11.9 17.6 31.3 9.8 61.3 33.1 32.1 25.0 7.2 110.8 27.7 73.4 65.1 13.7 175.5 0.0 23.1 21.4 9.6 12.3 301.2 147.9 7.3 14.2 28.7 43.4 7.3 12.2 37.2 14.2 89.0 21.9 33.4 5.2 86.5 311.1 33.3 13.3 30.5 4.7 67.7 22.5 39.1 42.8 10.4 19.7 43.7 29.2 34.9 66.0 10.2 10.1 18.1 5.7 9.8 9.7 119.9 SHISA3 hShisa3 ENSG00000178343 "Shisa family member 3" A0PJX4 4 42397488-42402487 "Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.3;heart muscle: 15.5;kidney: 21.4" "Group enriched" "Detected in some" 7 "Distal tubular cells: 43.0;Fibroblasts: 19.4;Hepatic stellate cells: 55.0" "Cancer enhanced" "Detected in many" "lung cancer: 7.6;renal cancer: 7.8" "Group enriched" "Detected in all" 4 "midbrain: 13.3;thalamus: 10.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "AN3-CA: 219.6;PC-3: 130.4" "Region enriched" "Detected in many" 23 "olfactory bulb: 51.7" "Region enriched" "Detected in many" 8 "spinal cord: 21.4" HPA054754 Approved "Lipid droplets,Cytosol" NA Yes "Cluster 24: B-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 43: Cardiomyocytes - Nuclear processes" Cytosol "Lipid droplets" "HPA054754: AB_2682593" "unprognostic (9.04e-3)" "unprognostic (3.47e-3)" "unprognostic (1.37e-1)" "unprognostic (1.80e-2)" "unprognostic (1.26e-1)" "unprognostic (6.78e-3)" "unprognostic (1.26e-2)" "unprognostic (2.86e-1)" "unprognostic (3.04e-1)" "unprognostic (1.37e-3)" "unprognostic (3.42e-2)" "unprognostic (1.95e-1)" "unprognostic (5.99e-2)" "unprognostic (5.32e-2)" "unprognostic (3.10e-2)" "unprognostic (1.64e-1)" "unprognostic (4.99e-3)" 4.1 1.8 1.8 1.8 1.6 0.0 2.3 1.1 1.6 0.7 1.2 6.2 2.2 0.2 0.3 1.7 0.5 1.0 15.5 1.0 2.2 21.4 0.6 5.7 7.0 1.7 13.3 0.3 0.2 0.2 0.6 0.0 2.6 0.8 3.0 0.1 0.6 1.0 1.6 0.5 10.4 4.3 1.4 0.4 2.9 0.6 10.1 0.1 5.0 1.4 0.8 3.5 1.3 1.2 0.0 0.0 0.0 219.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 23.7 0.1 0.0 0.0 23.3 0.0 0.0 0.0 2.6 0.0 0.1 0.0 6.6 0.0 0.8 0.4 0.0 0.0 0.0 0.0 5.2 0.3 0.0 0.0 0.0 0.0 1.2 0.0 10.1 0.0 130.4 0.2 0.0 0.0 9.0 0.0 0.1 0.3 0.0 0.0 0.0 8.1 0.1 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.6 1.1 1.6 1.0 2.2 1.7 13.3 2.6 1.4 10.1 1.2 4.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 2.2 0.0 0.0 3.7 0.0 0.0 0.1 0.1 43.0 0.0 0.0 0.1 2.5 3.7 0.0 5.3 0.0 0.0 0.0 19.4 0.5 0.1 0.0 1.1 55.0 0.2 0.1 0.0 0.1 0.1 0.0 0.6 0.3 0.0 3.4 0.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.3 0.0 0.0 2.4 0.0 0.1 0.0 0.2 1.4 0.5 0.4 0.1 0.0 0.0 0.0 2.4 0.1 0.0 SLBP HBP ENSG00000163950 "Stem-loop binding protein" Q14493 4 1692731-1712344 "Predicted intracellular proteins" "mRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 263.6;Spermatogonia: 294.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019254, HPA061670" Supported Supported Nucleoplasm,Nucleoli,Cytosol Yes Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli, Cytosol" "HPA019254: AB_1856951, HPA061670: AB_2684581" "unprognostic (1.81e-2)" "unprognostic (6.80e-3)" "unprognostic (2.05e-2)" "unprognostic (1.59e-1)" "unprognostic (1.94e-1)" "unprognostic (7.09e-3)" "prognostic unfavorable (2.29e-5)" "unprognostic (5.53e-2)" "unprognostic (1.94e-2)" "unprognostic (1.13e-2)" "unprognostic (9.81e-3)" "unprognostic (9.55e-3)" "unprognostic (4.58e-2)" "unprognostic (7.31e-2)" "unprognostic (1.95e-1)" "unprognostic (1.44e-1)" "unprognostic (7.07e-2)" 29.9 26.4 38.6 37.6 40.2 114.2 26.7 38.0 65.7 28.4 34.4 30.6 23.9 27.3 32.9 35.9 27.6 21.9 18.4 40.9 43.6 35.1 33.9 27.2 71.7 36.4 39.1 28.0 24.4 24.0 26.7 42.0 39.3 22.8 30.6 17.1 25.6 25.3 22.6 37.7 25.6 28.8 37.7 28.3 26.9 63.1 41.8 53.5 27.3 19.2 69.5 35.0 28.0 41.1 132.7 53.9 76.6 80.7 65.3 70.0 81.9 120.1 92.5 131.4 133.8 120.3 144.7 180.6 67.4 96.0 150.9 77.8 147.0 103.0 154.1 75.4 98.5 215.9 63.3 123.6 82.6 208.3 102.8 55.0 84.7 98.1 67.3 74.4 76.5 108.8 172.7 170.3 163.2 52.8 314.6 200.6 97.4 136.7 108.6 241.1 126.3 105.3 131.0 99.5 86.1 69.3 95.4 59.6 69.5 96.8 99.0 127.7 66.3 108.0 63.8 116.1 180.4 107.4 192.2 428.3 99.6 176.0 106.0 25.7 65.4 47.5 47.1 49.7 43.3 51.6 59.7 64.8 50.6 37.8 50.6 49.6 95.8 46.3 44.8 42.2 77.9 75.4 38.6 40.2 38.0 65.7 40.9 43.6 36.4 39.1 39.3 37.7 41.8 41.1 35.2 16.0 18.8 7.2 96.3 105.2 96.3 38.8 61.5 19.4 35.9 34.0 8.2 27.1 23.6 36.8 25.0 166.3 80.5 28.8 107.6 50.6 75.9 38.8 34.9 36.1 35.9 146.0 14.6 31.3 51.8 49.1 53.5 55.5 23.5 45.9 30.0 27.0 81.3 25.2 15.1 33.6 44.7 36.8 58.6 41.6 44.1 60.3 65.8 6.5 64.4 27.4 43.3 9.0 14.4 38.7 25.3 44.0 94.2 88.6 22.5 55.4 16.3 13.6 13.1 46.3 43.8 263.6 294.0 84.1 105.8 44.7 96.6 33.2 44.1 76.5 SLC29A2 "DER12, ENT2, HNP36" ENSG00000174669 "Solute carrier family 29 member 2" Q14542 11 66362521-66372214 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skeletal muscle: 90.8;tongue: 47.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 46.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 44.3;CAPAN-2: 53.5;T-47d: 55.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018168 Approved Uncertain Nucleoplasm NA Yes "Cluster 32: T-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 1: K-562 - Erythropoiesis" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA018168: AB_1857077" "unprognostic (3.20e-2)" "unprognostic (4.50e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (3.37e-1)" "unprognostic (5.08e-2)" "unprognostic (5.64e-2)" "unprognostic (1.60e-1)" "unprognostic (1.96e-1)" "unprognostic (2.09e-1)" "unprognostic (1.76e-1)" "unprognostic (5.28e-2)" "prognostic favorable (2.78e-4)" "unprognostic (2.55e-2)" "unprognostic (1.59e-1)" "unprognostic (1.13e-1)" "unprognostic (6.38e-3)" 6.7 0.9 4.2 2.5 4.3 0.8 7.4 9.8 5.6 1.9 4.2 5.7 7.8 0.9 3.1 3.3 3.6 1.4 11.9 4.1 4.0 6.9 1.5 4.4 2.8 7.4 6.9 0.7 8.7 12.9 6.1 4.1 8.2 5.2 4.1 3.1 7.2 2.4 90.8 2.8 7.4 0.3 4.1 2.1 9.4 0.5 5.9 2.3 5.4 47.3 1.9 1.2 2.6 3.7 14.2 11.4 8.2 1.8 1.2 0.3 44.3 0.6 0.0 0.4 0.6 20.2 53.5 6.1 10.4 0.1 3.1 12.9 11.4 9.7 0.0 0.5 18.6 11.7 12.4 1.5 1.3 21.9 0.4 0.7 4.3 1.5 4.1 5.2 0.5 5.1 33.0 0.0 0.0 34.5 1.6 31.9 21.8 35.1 8.1 1.3 0.3 26.4 22.2 10.4 16.1 6.6 1.0 18.4 1.2 2.4 55.2 4.1 0.0 0.3 11.2 0.4 0.0 0.3 0.8 0.5 0.9 0.5 0.7 0.0 0.0 0.0 1.3 0.0 0.4 0.2 0.7 1.7 0.3 0.7 1.7 1.7 0.1 0.0 0.0 0.6 0.1 0.5 4.2 4.3 9.8 5.6 4.1 4.0 7.4 6.9 8.2 4.1 5.9 3.7 0.6 3.2 6.3 9.4 2.2 0.6 4.7 5.4 1.2 2.5 7.6 5.8 12.3 4.3 6.5 14.7 12.5 46.4 0.7 6.0 3.9 5.0 0.1 2.1 0.5 0.9 2.4 2.1 11.2 6.7 16.5 1.7 11.2 5.4 4.5 1.8 0.4 0.9 4.4 5.0 10.8 9.2 4.1 0.8 0.4 0.0 0.0 0.5 0.0 2.8 0.9 2.3 0.0 7.5 0.8 3.5 4.7 0.4 1.5 4.7 1.6 0.5 3.8 3.7 0.0 4.4 2.1 0.4 0.5 3.5 0.0 13.5 2.1 0.4 10.6 3.4 SLC43A3 "DKFZp762A227, Eeg1, FOAP-13, PRO1659, SEEEG-1" ENSG00000134802 "Solute carrier family 43 member 3" Q8NBI5 11 57406954-57427580 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 146.9" "Cell type enhanced" "Detected in many" "Ductal cells: 75.5;granulocytes: 67.0;Hofbauer cells: 73.7;Langerhans cells: 74.6;Sertoli cells: 65.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 105.7;intermediate monocyte: 127.0;myeloid DC: 85.8;non-classical monocyte: 146.3;plasmacytoid DC: 85.7" "Group enriched" "Detected in all" 4 "dendritic cells: 85.8;monocytes: 146.3" "Cell line enhanced" "Detected in many" "HL-60: 513.8;HMC-1: 428.4;RPMI-8226: 570.9;WM-115: 532.1" "Region enhanced" "Detected in many" "olfactory bulb: 10.3" "Low region specificity" "Detected in all" "HPA030551, HPA077244" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Nucleoplasm, Plasma membrane" "HPA030551: AB_10604094, HPA077244: AB_2732335" "unprognostic (2.64e-1)" "unprognostic (7.63e-2)" "unprognostic (9.67e-3)" "unprognostic (7.41e-3)" "unprognostic (6.59e-3)" "unprognostic (5.30e-3)" "unprognostic (1.29e-1)" "unprognostic (4.91e-2)" "unprognostic (1.36e-1)" "unprognostic (2.26e-1)" "unprognostic (5.73e-2)" "unprognostic (3.97e-2)" "prognostic unfavorable (3.97e-13)" "unprognostic (8.16e-2)" "unprognostic (1.77e-1)" "unprognostic (8.34e-2)" "unprognostic (1.00e-1)" 61.4 16.8 5.2 34.8 5.9 58.0 50.3 5.9 7.3 40.2 6.8 23.7 8.3 28.1 4.5 34.8 30.0 28.5 34.8 5.5 7.1 15.9 146.9 46.9 26.5 6.7 6.4 24.3 13.7 3.9 4.9 14.3 7.3 14.4 11.8 0.9 35.2 7.5 15.6 34.6 20.6 25.5 6.3 20.8 20.1 4.7 11.1 23.2 76.3 13.3 28.9 30.7 28.2 8.5 289.2 0.0 16.0 0.4 52.9 76.9 0.7 22.0 93.0 31.6 54.1 0.0 61.4 165.0 9.8 52.0 16.3 161.8 47.0 28.8 63.3 1.0 0.2 257.3 93.0 0.0 106.6 513.8 428.4 231.7 0.9 306.5 3.5 22.9 89.7 75.0 299.8 154.4 123.7 0.6 108.6 328.2 24.3 0.0 5.3 221.8 3.3 570.9 76.1 0.0 38.0 0.0 62.2 1.4 263.5 1.5 24.1 77.3 48.1 1.5 81.4 209.2 62.5 0.3 0.9 41.3 187.3 183.2 532.1 15.2 105.7 23.4 19.6 127.0 22.2 9.6 13.5 26.8 85.8 7.1 10.4 10.5 9.0 3.9 146.3 85.7 26.5 60.7 5.2 5.9 5.9 7.3 5.5 7.1 6.7 6.4 7.3 6.3 11.1 8.5 19.8 16.0 49.1 1.6 6.1 46.8 7.4 30.8 48.3 0.5 8.0 14.2 3.7 28.6 26.1 1.8 0.0 0.6 11.9 0.3 0.0 75.5 1.0 1.0 3.1 33.0 0.0 38.3 0.1 6.4 5.0 33.4 2.0 3.0 67.0 2.9 14.3 61.7 73.7 0.0 0.2 0.6 16.2 21.0 74.6 1.7 9.9 47.0 30.2 8.4 10.2 0.6 3.1 8.5 0.8 9.4 0.5 12.4 22.5 14.5 0.0 0.1 4.9 0.1 65.7 15.5 22.0 0.7 1.1 13.6 17.6 0.8 11.8 12.3 1.2 3.0 SLC9A3R1 "EBP50, NHERF, NHERF1" ENSG00000109062 "SLC9A3 regulator 1" O14745 17 74748628-74769353 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Wnt signaling pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 352.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 295.8;Proximal enterocytes: 536.9;Proximal tubular cells: 433.0;Squamous epithelial cells: 303.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 572.4;SK-BR-3: 450.7;T-47d: 873.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001962, HPA009672, HPA027247" Enhanced Approved "Vesicles,Plasma membrane,Centriolar satellite" NA Yes 940000 "Cluster 2: Granulocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "Vesicles, Centriolar satellite" "CAB001962: , HPA009672: AB_1857215, HPA027247: AB_10601162" "unprognostic (1.29e-1)" "unprognostic (4.58e-2)" "unprognostic (1.73e-2)" "unprognostic (5.51e-2)" "unprognostic (5.83e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (9.83e-5)" "unprognostic (7.41e-2)" "unprognostic (5.61e-2)" "unprognostic (5.38e-2)" "unprognostic (7.53e-2)" "unprognostic (4.49e-2)" "unprognostic (1.56e-3)" "unprognostic (7.81e-3)" "unprognostic (5.53e-2)" "unprognostic (3.84e-2)" "unprognostic (2.08e-2)" 27.0 146.3 98.9 43.7 103.0 115.7 64.1 105.6 118.1 58.3 127.5 85.1 257.8 22.6 26.0 352.8 89.7 96.6 24.3 98.3 91.0 203.5 269.2 26.5 67.9 100.2 97.6 11.1 85.4 110.3 20.8 33.6 95.6 43.9 59.3 13.0 192.2 71.1 5.2 51.1 274.4 11.6 92.2 61.1 78.2 22.5 102.0 57.7 21.4 10.0 89.2 25.7 103.3 106.1 102.1 82.6 40.4 42.1 23.9 17.5 179.9 24.1 22.4 60.3 58.2 259.6 59.6 22.2 23.9 51.4 32.3 142.2 69.8 46.4 28.3 25.9 66.2 167.4 210.9 350.8 48.6 110.3 108.9 14.4 25.6 48.0 20.6 124.9 50.2 65.8 54.0 115.9 93.8 572.4 262.5 246.7 36.1 286.3 47.6 28.0 45.4 100.6 83.5 71.7 34.6 45.3 25.2 450.7 51.9 110.4 873.8 87.3 17.0 18.7 53.5 43.8 40.2 200.0 98.9 40.9 30.2 145.4 11.2 581.6 91.9 440.8 421.5 133.0 279.8 58.6 255.5 360.4 87.8 52.1 147.5 266.1 318.8 308.8 172.1 90.8 309.0 345.9 98.9 103.0 105.6 118.1 98.3 91.0 100.2 97.6 95.6 92.2 102.0 106.1 12.3 6.4 17.2 29.0 41.8 46.1 21.4 128.7 50.1 2.2 135.3 78.7 17.8 163.0 120.8 31.3 4.2 74.5 122.9 295.8 66.5 194.9 15.8 61.8 7.8 12.0 18.7 24.8 0.4 99.0 56.6 24.7 45.3 85.0 25.3 7.3 7.9 190.6 85.4 5.0 0.5 58.0 105.8 25.7 18.8 9.9 8.7 43.5 28.4 3.7 27.0 86.2 203.9 5.0 11.4 76.5 143.8 41.8 151.1 27.5 536.9 433.0 76.0 5.0 6.6 27.6 20.0 22.5 19.5 303.4 57.4 111.5 126.1 17.1 57.1 34.6 SLIRP "C14orf156, DC50" ENSG00000119705 "SRA stem-loop interacting RNA binding protein" Q9GZT3 14 77708071-77761104 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1099.6;Proximal tubular cells: 1027.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020291 Approved Supported Mitochondria No Yes 32000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA020291: AB_1845563" "unprognostic (9.28e-2)" "unprognostic (4.88e-2)" "unprognostic (1.87e-1)" "unprognostic (3.62e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (4.88e-4)" "unprognostic (1.18e-1)" "unprognostic (8.23e-2)" "unprognostic (2.19e-1)" "unprognostic (1.14e-2)" "unprognostic (1.92e-2)" "unprognostic (1.35e-1)" "unprognostic (9.95e-3)" "unprognostic (1.52e-1)" "unprognostic (2.39e-1)" "unprognostic (3.60e-2)" "unprognostic (1.37e-1)" 121.9 131.0 241.0 80.4 251.7 122.7 155.0 250.5 391.0 92.8 228.9 161.3 112.5 91.5 196.3 163.7 89.6 68.3 336.8 249.8 251.6 203.0 211.2 81.1 82.8 251.4 247.5 82.0 110.5 145.2 120.2 91.9 248.6 95.7 141.3 109.9 105.0 90.3 364.5 92.1 107.6 97.0 248.2 92.9 140.2 122.9 245.9 97.4 94.6 442.3 113.5 123.8 101.8 261.2 422.5 867.3 340.9 330.8 226.0 227.7 441.2 240.0 234.8 484.1 419.6 1187.1 387.1 314.2 238.9 284.7 295.6 415.7 645.4 508.0 647.3 166.5 717.2 316.3 816.1 1199.5 343.4 211.8 216.6 242.5 332.3 387.3 428.2 232.4 408.7 403.2 321.2 172.8 430.0 1442.6 325.3 562.2 525.1 938.0 1211.5 294.8 282.9 345.6 508.8 840.3 425.5 274.1 253.3 533.0 360.3 373.7 555.7 360.9 227.0 237.1 422.5 254.0 416.9 184.8 374.7 605.0 325.7 407.2 309.6 88.9 276.1 103.9 105.2 275.3 112.0 169.4 139.0 104.6 239.8 143.1 143.4 120.3 87.8 93.3 288.8 247.4 154.9 216.2 241.0 251.7 250.5 391.0 249.8 251.6 251.4 247.5 248.6 248.2 245.9 261.2 130.4 109.0 140.0 8.5 112.3 178.8 164.5 542.9 92.8 68.8 168.8 154.3 1099.6 270.2 303.9 264.8 47.9 393.0 82.7 330.9 770.9 405.1 548.5 163.7 141.9 169.0 246.8 203.2 10.8 530.1 382.3 166.0 119.3 123.7 171.5 73.1 179.2 793.4 313.6 43.7 9.6 373.1 388.6 202.8 119.5 123.0 168.0 135.2 250.8 2.8 211.4 206.4 93.7 8.5 16.7 440.6 334.4 170.0 136.9 190.5 563.3 1027.1 254.5 126.8 170.9 178.6 202.7 382.6 210.3 178.5 214.4 240.5 80.6 84.7 404.0 163.8 SMCO4 "C11orf75, FN5" ENSG00000166002 "Single-pass membrane protein with coiled-coil domains 4" Q9NRQ5 11 93478472-93543391 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 195.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 211.3;Paneth cells: 165.3;Proximal enterocytes: 200.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 113.7" "Low region specificity" "Detected in all" HPA041120 Uncertain NA Yes "Cluster 7: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 45: Enterocytes - Digestion" "HPA041120: AB_2677309" "unprognostic (7.45e-2)" "unprognostic (1.70e-3)" "unprognostic (2.54e-1)" "unprognostic (1.01e-2)" "unprognostic (1.58e-1)" "unprognostic (6.47e-2)" "unprognostic (8.56e-2)" "unprognostic (1.93e-1)" "unprognostic (3.43e-1)" "unprognostic (5.51e-1)" "unprognostic (4.23e-2)" "unprognostic (9.45e-2)" "prognostic unfavorable (5.81e-7)" "unprognostic (1.61e-1)" "unprognostic (3.05e-1)" "unprognostic (1.55e-2)" "unprognostic (5.01e-2)" 21.0 70.4 8.9 30.6 8.2 7.3 23.0 8.2 12.6 17.0 17.3 35.3 45.9 18.9 13.9 23.1 27.9 16.8 53.5 10.2 22.9 66.3 135.1 35.8 31.4 11.9 14.7 25.3 60.0 5.8 48.0 11.4 11.2 55.2 25.7 3.4 195.8 11.5 17.0 24.3 37.6 15.2 11.1 61.8 50.1 43.4 32.4 17.5 71.7 5.9 22.9 12.4 22.8 12.8 8.3 15.3 23.9 5.5 8.0 10.6 15.4 25.2 7.5 10.8 19.9 26.6 33.0 24.6 29.0 22.1 16.8 5.0 24.1 3.5 7.3 68.6 22.2 5.9 32.4 58.0 7.4 24.4 26.1 15.0 13.2 5.0 3.8 13.6 16.7 81.5 13.8 113.7 3.3 13.9 24.4 50.2 25.0 62.6 23.9 42.8 12.0 11.2 21.5 19.8 4.2 18.5 19.6 26.3 2.1 30.2 10.4 33.7 10.9 9.7 40.6 33.4 20.8 4.6 0.7 19.7 7.6 40.9 4.9 40.2 263.5 6.9 4.1 316.4 18.4 25.0 26.9 8.0 150.3 26.9 3.7 3.2 61.4 32.0 296.3 155.5 11.7 91.5 8.9 8.2 8.2 12.6 10.2 22.9 11.9 14.7 11.2 11.1 32.4 12.8 26.0 25.6 18.4 0.3 11.5 32.8 33.4 17.4 6.2 2.1 62.0 50.5 36.7 70.1 17.2 49.7 0.0 6.6 27.7 105.1 211.3 43.2 123.5 14.3 2.9 24.9 44.9 6.1 4.8 70.2 9.0 19.0 27.5 16.1 2.5 21.3 15.7 103.9 140.4 3.3 10.6 116.4 6.1 91.3 80.3 146.8 12.8 87.7 30.2 13.1 123.3 6.4 11.3 0.5 4.4 31.1 165.3 10.5 15.0 92.8 200.0 64.8 9.6 1.3 6.6 4.2 14.1 11.2 46.6 16.6 21.3 4.8 15.0 6.4 58.7 47.3 SOGA1 "C20orf117, dJ132F21.1, FLJ44670, KIAA0889, SOGA" ENSG00000149639 "Suppressor of glucose, autophagy associated 1" O94964 20 36777447-36863538 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 63.9" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 54.8;Oligodendrocytes: 50.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043992 Approved Approved Nucleoli,Cytosol "Secreted to blood" NA Yes "Cluster 21: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Nucleoli, Cytosol" "HPA043992: AB_2678762" "unprognostic (2.34e-2)" "unprognostic (1.35e-1)" "unprognostic (6.58e-2)" "unprognostic (1.73e-2)" "unprognostic (1.51e-1)" "unprognostic (1.48e-1)" "unprognostic (2.27e-3)" "unprognostic (1.37e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (8.28e-5)" "unprognostic (1.09e-3)" "unprognostic (2.85e-1)" "prognostic unfavorable (4.49e-4)" "unprognostic (6.99e-2)" "unprognostic (4.16e-2)" "unprognostic (1.40e-2)" "unprognostic (4.45e-3)" 6.6 14.2 13.4 3.6 18.1 1.1 6.2 63.9 16.4 9.5 0.0 12.3 1.9 10.9 3.8 7.0 9.6 4.8 9.5 12.8 14.4 7.8 0.9 6.2 2.5 14.6 15.0 10.4 2.8 7.3 4.9 6.2 12.6 9.0 2.8 4.5 4.7 8.8 2.4 8.6 5.8 8.4 8.8 4.6 6.4 7.9 15.1 2.9 12.2 3.9 3.1 11.2 7.4 21.9 13.4 18.0 21.5 23.2 12.2 11.2 5.6 11.6 12.5 16.1 9.5 7.3 2.1 6.0 4.2 20.4 14.0 17.8 17.3 10.8 16.8 0.9 3.4 9.7 18.5 9.7 6.4 2.1 9.0 6.3 13.0 15.4 10.9 7.0 10.6 6.5 6.9 1.2 17.8 13.0 6.9 5.1 5.5 1.3 13.8 16.1 19.9 2.3 9.5 4.0 25.5 15.9 24.1 26.1 7.5 9.4 33.3 14.4 16.3 40.2 7.7 19.9 25.7 2.4 0.6 5.8 17.1 2.8 26.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.0 13.4 18.1 63.9 16.4 12.8 14.4 14.6 15.0 12.6 8.8 15.1 21.9 16.5 0.0 1.8 18.9 4.4 12.6 5.4 6.3 13.6 26.3 9.6 8.9 16.1 5.7 6.7 20.2 37.5 15.6 11.3 1.7 1.9 3.8 0.9 8.6 20.5 14.5 6.0 1.3 19.9 1.5 10.2 12.0 0.5 21.9 10.8 33.0 10.4 0.6 10.0 23.5 30.3 1.5 0.0 7.6 10.7 2.4 12.2 8.1 5.4 21.5 4.5 17.8 0.0 54.8 50.9 1.4 2.4 18.8 1.8 6.0 2.1 1.5 3.9 3.8 13.1 23.2 16.9 0.5 1.3 13.7 16.1 3.3 1.4 14.0 3.0 2.9 SOX4 ENSG00000124766 "SRY-box transcription factor 4" Q06945 6 21593751-21598619 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 73.4" "Cell type enhanced" "Detected in many" "Ductal cells: 1128.5;Granulosa cells: 1047.5;Ionocytes: 1320.3;Pancreatic endocrine cells: 1288.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 45.7" "Group enriched" "Detected in all" 5 "dendritic cells: 45.7;granulocytes: 33.3;monocytes: 22.0" "Cell line enhanced" "Detected in many" "AN3-CA: 254.1;MOLT-4: 229.9" "Region enhanced" "Detected in all" "olfactory bulb: 54.2" HPA029901 Approved Supported Nucleoplasm,Mitochondria NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm Mitochondria "HPA029901: AB_10601592" "unprognostic (4.01e-2)" "unprognostic (3.06e-1)" "unprognostic (9.28e-2)" "unprognostic (5.18e-2)" "unprognostic (5.00e-2)" "unprognostic (1.08e-2)" "prognostic unfavorable (2.57e-5)" "unprognostic (1.78e-1)" "unprognostic (8.01e-3)" "unprognostic (1.98e-2)" "unprognostic (3.88e-3)" "unprognostic (1.18e-1)" "unprognostic (8.73e-3)" "unprognostic (3.66e-2)" "unprognostic (3.31e-1)" "unprognostic (2.01e-1)" "unprognostic (9.27e-2)" 11.8 4.3 4.7 9.2 5.0 24.0 17.9 8.8 6.7 21.5 2.8 11.9 12.5 57.8 15.0 5.4 13.5 20.4 6.4 4.2 6.5 16.8 6.4 19.3 5.8 3.5 5.0 51.7 10.2 3.6 4.1 6.1 4.1 14.5 14.4 6.4 17.5 6.8 3.5 8.8 11.6 17.4 4.0 5.4 17.5 9.9 7.1 73.4 8.6 6.1 7.4 21.1 7.7 4.2 8.5 24.4 60.5 254.1 22.0 5.5 98.7 3.8 7.8 4.6 4.1 16.7 16.5 2.9 100.2 6.2 3.5 25.1 32.0 17.9 3.3 36.6 66.8 2.7 11.5 11.2 3.5 9.0 2.1 9.6 18.1 2.1 7.3 64.1 72.3 138.8 0.6 0.2 5.2 20.6 229.9 21.6 45.3 12.7 23.1 99.7 5.3 0.4 44.1 78.3 78.9 141.2 35.9 41.1 14.0 74.9 20.1 30.9 55.7 7.1 23.1 1.7 18.6 1.5 0.1 71.8 2.4 30.6 28.5 33.3 19.3 2.1 0.5 11.7 0.1 7.0 0.3 0.3 8.7 6.6 2.2 1.6 0.8 7.4 22.0 45.7 2.1 4.7 4.7 5.0 8.8 6.7 4.2 6.5 3.5 5.0 4.1 4.0 7.1 4.2 235.0 198.7 50.4 0.7 36.2 112.5 129.2 660.7 676.7 99.7 586.1 676.5 297.4 423.2 457.3 154.5 12.5 74.8 104.4 247.6 66.5 1128.5 6.1 669.0 624.2 264.5 340.8 114.3 3.2 604.4 409.4 247.3 313.0 650.9 60.6 1047.5 119.2 6.8 35.5 48.8 4.6 263.0 1320.3 78.0 266.7 12.2 12.2 94.0 243.7 3.7 91.4 189.1 17.5 70.4 1.0 1288.2 153.8 11.3 40.9 151.1 76.7 132.5 162.1 31.6 6.6 234.2 439.9 4.9 236.8 400.7 93.1 30.2 36.6 69.6 299.4 272.5 SPDL1 "CCDC99, FLJ20364, hSpindly" ENSG00000040275 "Spindle apparatus coiled-coil protein 1" Q96EA4 5 169583636-169604778 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 35.5" "Cell type enhanced" "Detected in many" "Granulosa cells: 38.4;Spermatocytes: 112.9;Spermatogonia: 59.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA044700, HPA048146" Enhanced Approved Cytosol NA Yes "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA044700: AB_2679052, HPA048146: AB_2680284" "unprognostic (2.61e-2)" "unprognostic (1.94e-1)" "unprognostic (8.59e-3)" "prognostic unfavorable (1.18e-4)" "unprognostic (4.24e-1)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.48e-6)" "unprognostic (2.63e-3)" "unprognostic (5.70e-3)" "unprognostic (8.27e-3)" "prognostic unfavorable (1.19e-5)" "unprognostic (2.92e-2)" "prognostic unfavorable (2.13e-6)" "unprognostic (2.81e-1)" "unprognostic (3.13e-1)" "unprognostic (3.28e-2)" "unprognostic (2.93e-1)" 3.9 3.6 5.5 9.4 6.0 10.9 5.5 6.1 7.2 3.4 3.4 5.4 5.7 6.2 3.8 5.8 4.4 4.5 3.4 4.7 5.6 4.8 3.2 4.0 14.9 6.0 5.5 6.7 2.5 5.0 2.4 8.4 6.1 3.3 5.7 3.4 3.2 3.1 5.3 5.5 5.3 7.4 7.1 6.6 5.3 35.5 5.4 21.5 4.3 5.9 14.0 4.8 3.8 7.2 57.0 69.2 67.4 47.6 17.6 18.5 59.1 181.1 22.9 128.1 119.0 89.6 38.8 54.3 116.9 147.0 90.3 39.3 56.8 76.0 139.6 58.1 65.2 59.6 117.0 36.2 8.3 66.9 51.3 9.2 6.2 62.2 34.0 29.0 59.9 60.5 41.3 39.3 142.4 58.5 54.1 28.2 50.1 28.9 63.2 64.8 67.6 38.5 89.7 19.8 43.7 31.4 84.9 23.6 34.5 46.9 27.0 44.9 46.3 146.6 46.8 43.4 140.0 30.1 69.2 69.1 35.4 61.9 50.2 4.0 2.7 3.8 8.4 3.6 8.9 11.2 7.9 8.9 2.8 12.7 10.8 9.1 0.5 8.4 6.2 19.7 8.6 4.1 5.5 6.0 6.1 7.2 4.7 5.6 6.0 5.5 6.1 7.1 5.4 7.2 6.1 3.2 6.3 3.9 8.7 4.0 1.7 4.8 4.6 6.9 6.2 7.5 7.1 2.8 7.0 1.8 0.0 14.1 9.8 3.6 5.9 6.6 9.6 5.3 8.0 6.5 1.8 22.3 6.2 4.8 26.1 7.7 12.2 4.9 8.8 38.4 13.2 3.2 12.2 3.3 6.5 3.2 2.0 4.7 3.6 11.1 4.4 4.7 3.6 2.8 5.0 7.4 13.4 5.0 6.8 6.6 1.9 6.4 10.2 1.6 0.5 8.2 4.1 4.4 6.6 6.4 9.9 112.9 59.2 5.8 4.4 4.9 5.2 9.6 7.4 2.5 SPTBN1 ENSG00000115306 "Spectrin beta, non-erythrocytic 1" Q01082 2 54456317-54671446 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 615.4;Peritubular cells: 663.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012685, HPA013149" Supported Approved "Golgi apparatus" NA Yes 1500000 "Cluster 39: Non-specific - mRNA processing" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "HPA012685: AB_1857433, HPA013149: AB_1857434" "unprognostic (2.72e-1)" "unprognostic (4.44e-3)" "unprognostic (3.00e-2)" "unprognostic (3.25e-1)" "unprognostic (4.09e-2)" "unprognostic (7.95e-2)" "unprognostic (9.24e-2)" "unprognostic (3.72e-2)" "unprognostic (7.31e-2)" "unprognostic (1.67e-1)" "unprognostic (2.26e-2)" "unprognostic (7.25e-2)" "prognostic favorable (2.59e-5)" "unprognostic (2.31e-1)" "unprognostic (2.73e-1)" "unprognostic (1.68e-3)" "unprognostic (5.18e-3)" 187.3 70.9 210.6 34.7 205.1 37.6 78.7 97.4 166.1 54.1 94.2 62.8 32.7 52.0 36.3 41.7 56.2 69.2 135.9 156.2 99.7 65.3 83.8 131.6 28.9 141.2 154.4 73.2 45.5 129.2 27.8 97.4 120.4 43.8 52.4 56.0 55.1 74.4 54.0 39.4 46.8 59.9 134.8 58.7 55.6 32.6 214.6 29.3 72.8 87.2 30.0 45.6 38.6 163.6 96.5 150.5 60.4 57.2 234.7 158.8 74.8 40.2 82.3 63.7 61.4 101.7 66.6 0.4 112.1 142.0 55.1 110.9 85.1 128.0 66.0 0.8 35.6 43.7 118.4 166.2 97.7 59.7 24.4 62.3 64.8 193.8 119.7 77.6 151.6 95.1 50.0 64.0 86.1 21.6 105.0 14.5 66.3 129.6 70.2 116.2 95.0 37.2 92.2 120.6 36.3 113.3 121.5 39.5 88.1 58.9 19.6 9.9 235.2 89.9 79.0 110.2 58.2 62.8 42.8 32.7 98.1 17.7 163.7 2.3 0.4 2.8 3.7 0.0 3.9 3.7 3.4 3.6 1.3 3.5 5.0 3.6 0.6 5.2 0.0 1.1 3.2 3.1 210.6 205.1 97.4 166.1 156.2 99.7 141.2 154.4 120.4 134.8 214.6 163.6 615.4 407.1 124.6 233.4 45.7 83.1 50.0 64.7 42.7 94.4 60.8 58.0 262.9 144.4 100.6 145.3 73.0 28.3 31.7 343.6 7.9 223.7 12.1 140.4 80.3 426.4 83.1 21.5 231.3 121.9 42.0 271.6 139.7 115.7 35.4 68.2 228.5 184.6 14.2 141.3 195.4 135.5 77.3 17.7 47.0 31.5 503.2 16.6 147.7 294.2 9.7 131.9 36.0 154.8 283.1 243.3 109.9 663.5 76.3 75.6 142.8 44.1 187.3 93.6 164.3 340.3 171.9 54.7 53.3 79.7 68.2 11.1 49.2 56.6 151.9 88.1 SUN2 UNC84B ENSG00000100242 "Sad1 and UNC84 domain containing 2" Q9UH99 22 38734725-38794143 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 201.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001209 Supported Supported "Nuclear membrane" NA Yes "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear membrane" "HPA001209: AB_1080465" "unprognostic (9.76e-2)" "unprognostic (1.42e-1)" "unprognostic (8.32e-2)" "unprognostic (5.09e-2)" "unprognostic (1.36e-1)" "unprognostic (5.57e-2)" "unprognostic (1.94e-2)" "unprognostic (2.37e-2)" "unprognostic (3.14e-2)" "unprognostic (1.25e-3)" "unprognostic (8.15e-2)" "unprognostic (4.10e-2)" "unprognostic (1.06e-1)" "unprognostic (1.75e-1)" "unprognostic (1.31e-1)" "unprognostic (8.10e-2)" "unprognostic (2.33e-2)" 137.8 35.1 123.6 73.6 219.0 160.4 111.7 149.1 155.3 95.4 41.4 107.8 47.6 128.2 22.2 84.0 125.3 41.1 86.7 118.3 133.1 52.8 121.9 107.0 104.0 187.1 182.2 112.9 78.0 18.2 40.3 28.7 170.7 78.2 25.2 12.3 74.9 52.1 145.4 90.3 93.1 46.1 107.2 97.2 94.3 34.6 163.3 74.3 53.1 63.8 60.0 121.7 89.0 257.7 89.8 41.0 40.0 44.7 118.8 29.5 52.0 60.2 69.4 69.7 58.9 36.8 98.7 28.1 71.9 85.9 43.1 65.4 13.4 44.7 28.4 98.0 54.7 18.4 44.7 33.7 71.9 62.3 184.0 25.0 37.3 33.6 31.2 46.9 56.2 55.3 23.5 154.3 38.5 28.7 35.0 53.9 3.9 63.0 26.2 57.6 55.8 85.7 17.4 43.1 35.3 13.2 67.0 73.7 35.1 18.5 49.5 115.3 95.2 50.6 43.3 44.9 79.5 113.1 38.2 30.4 93.8 74.2 86.6 29.0 13.7 18.6 42.3 15.6 27.5 10.8 27.0 34.9 10.7 10.1 27.6 33.6 13.9 24.8 26.9 6.7 19.9 24.8 123.6 219.0 149.1 155.3 118.3 133.1 187.1 182.2 170.7 107.2 163.3 257.7 55.5 22.4 22.9 20.2 57.0 18.1 28.4 15.1 24.5 9.9 36.5 39.0 6.2 40.0 17.8 33.1 8.4 16.9 141.8 65.6 3.9 34.9 1.8 11.6 15.8 37.4 18.6 31.8 12.5 47.6 65.9 34.0 42.8 32.9 25.4 41.5 52.1 109.6 25.0 21.9 7.7 30.1 8.2 42.4 21.4 4.4 61.2 41.8 17.8 16.9 25.5 21.4 201.8 7.1 132.9 60.0 41.8 65.5 44.7 22.0 42.2 18.9 5.7 13.0 52.6 100.7 37.0 3.8 1.1 32.1 17.2 14.8 133.4 10.9 21.4 21.4 SURF4 "ERV29, FLJ22993, MGC102753" ENSG00000148248 "Surfeit 4" O15260 9 133361450-133376166 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 325.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064613 Approved Supported "Nuclear membrane,Endoplasmic reticulum,Golgi apparatus,Cytosol" NA Yes 65000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear membrane, Endoplasmic reticulum, Golgi apparatus" Cytosol "HPA064613: AB_2685299" "prognostic unfavorable (5.85e-4)" "unprognostic (1.38e-2)" "unprognostic (1.92e-1)" "unprognostic (2.04e-2)" "unprognostic (3.40e-2)" "prognostic unfavorable (1.47e-5)" "prognostic unfavorable (8.11e-4)" "unprognostic (1.10e-3)" "unprognostic (3.13e-2)" "unprognostic (1.90e-1)" "unprognostic (5.30e-3)" "unprognostic (1.23e-1)" "unprognostic (9.76e-3)" "unprognostic (7.58e-3)" "unprognostic (1.25e-1)" "unprognostic (2.29e-1)" "unprognostic (4.29e-3)" 97.0 106.4 20.3 38.8 22.5 66.5 76.5 22.1 23.4 70.5 27.9 72.1 79.2 78.5 40.6 77.6 71.1 39.0 74.1 21.5 22.3 67.1 223.8 84.2 29.6 23.6 22.2 61.0 150.4 35.4 88.6 55.4 22.2 69.2 37.9 14.0 86.4 39.5 60.1 63.2 82.2 43.4 22.9 59.6 88.5 49.4 25.8 27.8 68.2 23.3 31.4 62.7 59.4 25.9 59.8 96.4 65.3 90.3 134.8 140.2 127.4 184.1 178.4 127.0 124.7 145.9 84.8 41.1 70.6 254.2 122.9 152.7 75.7 94.4 97.0 86.5 46.3 72.1 87.1 156.5 156.2 124.8 94.1 150.4 85.8 109.3 120.2 101.6 118.6 62.9 89.0 109.8 164.5 131.8 60.1 115.4 72.7 162.8 96.2 41.2 89.9 156.5 100.4 56.3 53.8 65.5 136.4 100.4 95.2 61.5 106.6 75.8 127.5 179.4 64.5 137.3 119.6 56.1 86.4 46.4 166.7 66.6 137.5 43.9 40.8 36.2 51.9 32.8 56.9 15.1 36.3 48.4 32.9 12.1 22.0 34.6 28.4 29.4 31.7 38.9 46.9 68.8 20.3 22.5 22.1 23.4 21.5 22.3 23.6 22.2 22.2 22.9 25.8 25.9 53.5 44.8 48.1 18.9 43.0 60.8 65.8 72.5 46.1 21.9 55.5 43.2 42.6 31.5 47.5 35.0 39.6 167.9 80.4 106.9 19.6 95.7 38.6 28.6 72.8 54.8 75.2 31.1 23.2 118.1 254.4 84.8 78.5 67.7 24.7 49.5 47.5 207.3 85.9 33.7 15.6 107.9 30.5 52.3 50.5 19.7 68.3 50.8 40.9 17.8 53.7 53.3 52.5 22.6 23.8 115.1 65.5 53.0 114.8 106.8 151.3 48.5 23.2 26.9 78.9 51.9 80.6 84.4 47.3 46.1 62.4 325.2 90.5 81.8 81.2 84.2 SYTL4 ENSG00000102362 "Synaptotagmin like 4" Q96C24 X 100674491-100732123 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 68.3" "Cell type enhanced" "Detected in many" "Granulosa cells: 58.1;Leydig cells: 72.7;Sertoli cells: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.7" "Lineage enriched" "Detected in single" 10 "granulocytes: 1.7" "Cell line enhanced" "Detected in many" "HAP1: 29.5;HMC-1: 60.0;RT4: 40.8;TIME: 34.9" "Region enriched" "Detected in many" 5 "hypothalamus: 30.1" "Low region specificity" "Detected in all" "HPA001475, HPA001589, HPA075138" Approved Approved Vesicles NA Yes 3300000 "Cluster 1: Neutrophils - Mixed function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA001475: AB_1080172, HPA001589: AB_1080174, HPA075138: " "unprognostic (7.82e-3)" "unprognostic (1.52e-1)" "unprognostic (3.43e-2)" "unprognostic (6.16e-2)" "unprognostic (1.04e-1)" "unprognostic (1.14e-1)" "unprognostic (5.78e-2)" "unprognostic (1.32e-1)" "unprognostic (3.35e-2)" "unprognostic (2.81e-1)" "unprognostic (1.07e-3)" "unprognostic (5.62e-2)" "prognostic unfavorable (2.09e-4)" "unprognostic (1.30e-1)" "unprognostic (1.56e-1)" "unprognostic (1.67e-1)" "unprognostic (1.60e-2)" 6.9 4.1 6.9 2.2 13.2 2.3 6.0 4.5 5.1 21.7 14.1 9.8 2.1 43.1 3.1 3.9 17.8 4.0 3.2 5.2 13.1 5.6 10.5 4.7 0.7 8.4 9.3 68.3 8.3 1.2 18.8 3.6 7.4 12.7 9.7 1.3 6.1 7.2 2.3 2.0 4.9 32.7 6.1 3.3 7.4 6.8 18.0 0.6 8.8 4.9 1.7 6.1 10.2 7.9 0.3 6.0 1.6 0.0 8.5 4.8 0.1 7.7 4.9 8.0 14.3 0.7 7.6 0.0 2.0 5.4 6.9 6.8 29.5 2.3 8.4 0.0 2.6 0.1 10.8 0.4 2.1 0.0 60.0 1.7 0.5 7.3 0.4 3.1 20.5 0.0 3.0 0.0 3.8 2.0 0.1 0.0 1.2 21.2 0.0 0.0 2.4 0.0 7.0 40.8 14.5 0.6 3.1 11.5 1.7 3.0 7.1 0.6 34.9 4.2 8.8 20.9 1.9 0.1 0.0 0.1 5.2 0.0 4.8 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 1.7 0.1 0.0 0.0 0.0 0.8 6.9 13.2 4.5 5.1 5.2 13.1 8.4 9.3 7.4 6.1 18.0 7.9 15.6 28.9 1.7 41.8 0.5 0.1 7.7 3.1 1.2 0.2 19.0 6.6 3.8 18.6 8.0 3.7 0.0 0.4 0.7 29.1 3.9 8.9 1.6 4.3 25.8 13.5 0.0 5.0 0.5 2.3 0.4 20.0 26.5 6.2 3.8 58.1 11.4 38.6 1.3 0.0 1.0 26.9 8.2 1.6 1.9 3.8 72.7 7.2 3.6 8.4 0.5 5.4 0.0 10.6 0.2 7.2 27.1 41.8 0.5 11.9 5.8 2.6 8.1 0.6 52.6 38.1 11.8 2.6 4.4 2.6 0.9 0.0 0.9 18.0 9.6 13.8 TACC3 "ERIC-1, ERIC1, maskin, Tacc4" ENSG00000013810 "Transforming acidic coiled-coil containing protein 3" Q9Y6A5 4 1712891-1745171 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 58.9;lymphoid tissue: 52.4;testis: 50.6" "Cell type enhanced" "Detected in many" "Early spermatids: 70.4;Hofbauer cells: 43.9;Late spermatids: 69.9;Spermatocytes: 94.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005781, HPA006050, CAB010111, HPA022039" Enhanced Enhanced "Vesicles,Mitotic spindle,Centriolar satellite,Cytosol" Yes Yes 11000 "Cluster 5: Granulocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Mitotic spindle, Centriolar satellite, Cytosol" Vesicles "CAB010111: AB_628323, HPA005781: AB_1857724, HPA006050: AB_2667505, HPA022039: AB_1857725" "unprognostic (2.95e-1)" "unprognostic (1.18e-1)" "unprognostic (7.71e-2)" "unprognostic (4.35e-2)" "unprognostic (6.58e-2)" "unprognostic (1.84e-2)" "prognostic unfavorable (3.30e-4)" "unprognostic (1.10e-3)" "unprognostic (4.61e-2)" "unprognostic (9.12e-2)" "unprognostic (2.91e-2)" "unprognostic (2.26e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.66e-2)" "unprognostic (2.09e-1)" "unprognostic (4.44e-3)" "unprognostic (9.75e-2)" 5.3 3.9 4.2 24.9 4.3 58.9 3.5 5.2 5.3 3.6 5.2 10.3 6.6 3.3 4.8 14.9 2.8 4.2 3.3 4.5 4.4 2.7 3.5 6.5 43.2 4.8 5.3 2.2 1.4 2.3 2.6 8.7 4.8 2.4 10.6 1.9 3.9 2.5 2.0 6.4 12.9 6.4 4.2 22.1 6.4 50.6 5.1 52.4 2.8 3.4 39.3 5.0 5.4 4.7 106.7 88.7 129.5 72.2 6.7 15.2 72.9 114.6 62.1 135.4 87.6 93.5 122.8 133.8 48.0 65.4 149.9 71.4 142.5 86.8 131.1 59.8 77.0 113.8 67.2 85.8 5.9 146.6 85.5 5.2 5.7 85.6 46.0 26.0 102.2 110.3 106.3 90.8 123.8 87.1 207.5 204.0 139.3 89.2 111.6 139.1 90.5 55.0 73.8 125.5 99.8 62.8 70.1 42.3 33.1 95.2 83.3 90.5 56.4 75.4 90.0 65.4 176.7 69.5 102.5 207.1 43.2 141.1 109.1 45.5 30.0 37.9 8.5 12.5 11.1 7.8 16.5 11.5 15.3 10.8 28.3 13.1 91.8 12.2 9.6 8.3 42.5 32.5 4.2 4.3 5.2 5.3 4.5 4.4 4.8 5.3 4.8 4.2 5.1 4.7 6.0 0.0 6.7 2.0 16.5 2.2 1.2 3.2 1.2 1.7 2.4 3.0 2.6 2.8 3.4 9.2 8.4 19.5 6.4 11.2 0.0 2.2 70.4 4.2 2.8 5.2 1.2 37.2 2.3 0.7 20.4 6.0 12.8 4.3 5.1 24.5 8.9 5.1 43.9 5.0 3.2 9.5 4.1 23.2 10.8 69.9 2.8 34.1 0.0 4.7 24.4 1.4 6.2 0.5 0.8 2.9 4.2 2.6 18.0 1.3 2.6 2.8 0.9 2.7 6.6 2.0 4.8 94.3 37.7 12.8 1.4 4.0 23.2 2.2 16.1 2.7 TBKBP1 "KIAA0775, ProSAPiP2" ENSG00000198933 "TBK1 binding protein 1" A7MCY6 17 47694081-47712050 "Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 62.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062347, HPA064856" Approved Approved Nucleoplasm NA Yes "Cluster 1: Neutrophils - Mixed function" "Cluster 47: Non-specific - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA062347: AB_2684744, HPA064856: AB_2685371" "unprognostic (2.14e-3)" "unprognostic (1.15e-1)" "unprognostic (2.42e-2)" "unprognostic (1.92e-2)" "unprognostic (2.39e-1)" "unprognostic (3.09e-2)" "unprognostic (3.72e-1)" "unprognostic (1.05e-1)" "unprognostic (1.51e-1)" "unprognostic (3.24e-1)" "prognostic favorable (8.14e-6)" "unprognostic (5.83e-2)" "unprognostic (1.14e-1)" "unprognostic (3.03e-1)" "unprognostic (4.22e-1)" "unprognostic (1.56e-1)" "prognostic favorable (1.59e-5)" 13.9 10.9 25.2 8.5 22.3 6.7 12.0 11.4 29.9 17.1 6.3 15.3 3.1 14.0 2.1 11.3 14.2 8.1 16.4 27.3 19.3 12.9 3.4 12.3 6.0 18.4 19.8 21.4 9.6 10.1 11.6 9.5 18.2 13.4 2.2 10.4 15.9 9.3 35.5 7.4 7.8 7.9 11.6 18.4 10.5 14.2 24.4 3.2 11.7 22.3 3.4 14.9 12.3 18.5 0.5 10.0 18.3 19.4 9.2 9.3 11.9 10.1 10.6 4.9 5.8 62.8 1.5 0.3 9.9 12.6 8.7 1.1 14.4 2.6 2.9 12.3 32.6 26.8 9.8 10.7 21.2 5.1 5.7 18.8 6.5 1.1 1.8 15.2 17.4 7.3 23.5 0.0 2.8 2.8 3.3 25.2 25.5 0.5 7.0 12.0 5.7 10.5 6.1 0.8 15.8 29.5 4.8 1.2 5.2 17.2 11.0 11.4 20.2 15.1 17.8 18.4 1.2 6.8 0.7 12.4 8.8 9.6 3.9 0.0 0.2 0.4 1.0 0.1 0.5 0.0 0.3 0.8 0.2 0.2 0.1 0.3 2.2 0.9 0.0 0.2 0.2 0.1 25.2 22.3 11.4 29.9 27.3 19.3 18.4 19.8 18.2 11.6 24.4 18.5 15.5 0.0 1.1 13.4 2.4 4.0 3.2 0.9 1.8 13.7 2.8 3.4 3.7 1.5 1.1 3.7 2.1 0.1 6.3 0.0 1.9 1.1 6.9 0.7 3.5 9.7 5.3 3.2 6.9 1.8 0.2 3.9 2.6 1.2 0.0 4.2 10.4 1.1 3.2 28.6 12.1 0.5 4.1 2.9 4.0 6.6 8.7 2.2 1.8 5.6 1.1 4.7 5.2 9.5 1.2 0.9 0.0 8.6 2.2 5.5 0.0 5.0 0.8 3.7 0.0 1.5 2.7 3.8 5.3 2.0 3.0 0.3 3.9 1.3 0.1 2.2 TIFA "MGC20791, T2BP, T6BP, TIFAA" ENSG00000145365 "TRAF interacting protein with forkhead associated domain" Q96CG3 4 112274537-112285904 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 86.6;Syncytiotrophoblasts: 79.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 137.4;U-698: 123.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045889 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Nucleoli" Cytosol "HPA045889: AB_10963785" "unprognostic (2.41e-2)" "unprognostic (2.47e-2)" "unprognostic (4.13e-2)" "unprognostic (3.23e-2)" "unprognostic (2.86e-1)" "unprognostic (4.98e-3)" "unprognostic (1.05e-1)" "unprognostic (2.25e-1)" "unprognostic (2.48e-2)" "unprognostic (2.14e-2)" "unprognostic (4.60e-3)" "unprognostic (5.26e-2)" "unprognostic (6.44e-3)" "unprognostic (1.52e-1)" "unprognostic (2.56e-1)" "unprognostic (2.99e-1)" "unprognostic (8.49e-3)" 6.4 6.3 2.0 19.9 1.8 40.6 13.7 4.3 2.1 7.7 4.3 7.0 6.7 5.6 2.1 15.6 6.8 7.5 10.7 2.3 2.4 5.2 11.3 10.2 32.2 2.3 2.1 9.3 41.3 11.5 2.1 14.2 2.5 6.7 6.9 2.8 34.8 3.7 3.8 9.3 8.8 5.3 2.1 11.7 10.3 2.1 2.3 15.4 21.1 6.4 34.6 11.6 7.7 2.3 21.9 5.5 7.9 13.4 9.5 7.7 15.9 17.0 32.0 10.6 18.1 2.8 19.1 66.3 13.5 6.8 15.5 6.3 10.9 13.0 22.1 54.1 6.4 6.6 12.4 6.2 6.4 21.2 8.8 10.4 7.0 11.4 12.3 18.0 17.0 18.1 6.8 137.4 14.3 11.0 37.3 11.5 1.6 13.4 7.0 63.7 19.9 44.7 23.6 14.7 18.1 18.6 13.7 28.2 6.6 3.4 12.2 29.9 12.7 16.7 19.8 14.2 13.6 85.3 84.8 123.8 15.7 13.8 12.6 6.8 7.2 4.0 11.1 5.2 18.1 38.2 20.4 19.4 13.2 40.4 9.0 11.6 21.4 17.4 6.8 12.3 33.9 11.3 2.0 1.8 4.3 2.1 2.3 2.4 2.3 2.1 2.5 2.1 2.3 2.3 35.7 19.2 27.4 0.0 44.8 21.3 15.7 27.8 43.9 1.4 31.6 30.9 15.4 12.8 15.7 12.9 0.0 47.9 23.4 4.4 19.6 16.5 0.1 10.0 9.6 31.8 9.0 7.6 1.4 24.4 20.9 22.3 14.8 21.0 3.8 5.4 6.4 10.7 17.8 0.0 0.6 8.4 28.5 13.0 29.7 1.4 9.0 13.1 33.8 2.8 7.1 12.5 11.3 0.5 0.1 11.4 8.0 10.9 86.6 29.2 11.0 9.5 8.8 0.6 6.6 27.2 10.5 2.5 3.8 39.2 26.0 79.4 35.9 5.7 7.0 15.1 TIPIN FLJ20516 ENSG00000075131 "TIMELESS interacting protein" Q9BVW5 15 66336191-66386746 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 98.0;Langerhans cells: 93.7;Spermatocytes: 120.6;Suprabasal keratinocytes: 108.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039704, HPA058799" Enhanced NA Yes "Cluster 24: B-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA039704: AB_10795258, HPA058799: AB_2683824" "unprognostic (3.47e-1)" "prognostic favorable (4.15e-4)" "unprognostic (3.49e-3)" "unprognostic (6.34e-2)" "unprognostic (1.87e-1)" "unprognostic (5.14e-2)" "prognostic unfavorable (2.47e-4)" "unprognostic (3.75e-1)" "unprognostic (1.32e-3)" "unprognostic (1.42e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (9.35e-4)" "unprognostic (2.18e-3)" "unprognostic (9.47e-2)" "unprognostic (1.09e-1)" "unprognostic (4.91e-1)" "unprognostic (2.89e-3)" 4.2 4.4 3.3 7.1 3.3 12.6 5.9 5.4 4.6 3.9 2.0 4.8 2.8 4.7 1.8 4.9 5.5 2.6 3.1 3.2 3.1 4.0 4.9 3.5 9.5 3.2 3.9 6.4 4.7 5.2 3.2 3.8 3.1 3.5 5.3 8.1 3.3 3.2 4.0 3.9 3.0 4.4 2.9 3.7 3.8 20.5 3.2 7.8 4.4 4.8 10.8 3.6 3.3 3.7 28.6 33.9 36.9 17.7 6.4 13.6 30.2 39.1 16.0 54.8 48.0 49.9 32.1 58.5 27.8 14.9 31.9 44.8 94.2 34.1 51.7 39.0 52.4 51.7 33.0 28.0 12.9 54.4 17.1 17.5 11.1 51.2 41.2 7.8 23.0 47.6 43.6 27.4 47.8 32.7 50.3 35.2 37.7 66.7 26.7 50.1 54.9 58.0 19.0 32.5 35.0 21.9 27.5 17.4 25.3 26.8 26.6 32.9 15.3 38.9 42.6 33.7 73.4 16.4 91.2 92.7 26.0 98.8 40.3 0.4 2.1 1.4 2.7 4.3 3.2 2.3 2.0 2.4 3.8 4.3 3.0 3.4 0.4 4.5 2.7 2.9 1.9 1.9 3.3 3.3 5.4 4.6 3.2 3.1 3.2 3.9 3.1 2.9 3.2 3.7 7.8 6.4 7.0 14.0 15.7 98.0 72.4 24.3 5.7 11.8 7.1 9.0 2.7 28.6 11.5 9.2 10.4 35.9 7.8 5.4 86.1 11.8 63.3 8.3 8.6 18.4 4.8 15.6 7.8 8.6 41.2 16.5 5.1 4.8 8.2 11.8 14.6 13.7 21.4 8.4 11.1 7.1 14.2 27.4 93.7 31.4 19.0 13.2 56.9 1.0 12.3 9.2 15.5 10.1 9.6 7.3 7.0 18.0 8.7 41.2 3.8 63.5 6.8 14.7 32.9 51.9 29.0 120.6 62.5 6.6 108.8 19.4 21.0 9.3 10.1 34.1 TLE3 "ESG, ESG3, GRG3, HsT18976, KIAA1547" ENSG00000140332 "TLE family member 3, transcriptional corepressor" Q04726 15 70047790-70098176 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 65.1" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 132.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 49.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 49.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054116 Approved Supported Nucleoplasm NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm "HPA054116: AB_2682386" "unprognostic (5.57e-2)" "prognostic favorable (2.09e-5)" "unprognostic (5.18e-2)" "unprognostic (5.13e-2)" "unprognostic (1.15e-1)" "unprognostic (4.05e-2)" "unprognostic (1.35e-2)" "unprognostic (5.53e-2)" "unprognostic (6.74e-2)" "unprognostic (3.11e-2)" "unprognostic (1.72e-1)" "unprognostic (6.07e-2)" "unprognostic (4.90e-2)" "unprognostic (2.43e-1)" "unprognostic (6.71e-2)" "unprognostic (6.29e-2)" "unprognostic (2.74e-1)" 16.1 6.4 9.2 18.3 11.5 65.1 15.2 10.7 10.9 17.4 2.9 20.6 17.3 10.8 3.0 31.1 10.1 5.8 9.9 12.3 15.3 16.4 13.3 20.3 17.7 15.1 13.9 14.0 14.9 5.8 10.3 12.6 11.8 23.2 6.4 4.9 19.1 10.1 8.3 29.4 21.8 6.9 13.4 23.1 15.7 22.1 15.1 13.5 13.5 2.9 18.9 9.8 19.4 12.2 7.8 24.2 13.3 23.6 12.1 9.9 80.3 1.5 4.1 3.1 2.5 34.0 22.8 22.0 32.8 2.1 4.8 14.3 32.3 11.5 1.6 30.9 45.9 36.9 50.8 6.6 11.5 11.4 51.1 20.5 6.3 9.1 8.2 19.7 15.5 47.9 26.1 96.0 4.5 20.9 41.2 28.3 14.2 7.4 24.9 36.8 13.6 24.7 7.1 41.7 19.5 28.7 66.2 29.7 28.7 14.5 33.6 24.9 11.7 9.5 18.7 29.6 16.4 84.6 57.2 35.3 13.3 37.3 25.1 2.6 4.5 2.5 1.9 4.8 1.8 9.9 2.6 2.5 2.9 4.9 2.5 3.3 49.1 2.8 5.2 8.7 1.6 1.7 9.2 11.5 10.7 10.9 12.3 15.3 15.1 13.9 11.8 13.4 15.1 12.2 27.5 12.8 27.7 16.0 49.2 115.1 47.8 19.5 59.2 19.9 45.5 28.4 8.1 4.3 18.9 62.5 31.3 25.3 38.2 55.2 7.9 11.6 45.5 17.2 5.0 27.6 28.8 15.2 6.1 5.6 64.4 25.0 17.9 32.1 53.2 25.5 23.9 21.5 37.3 0.0 5.0 30.3 10.2 41.5 78.2 76.9 14.0 51.5 35.6 13.1 35.8 32.6 1.0 9.5 0.4 11.0 31.7 18.4 47.2 39.9 41.0 13.2 8.1 4.4 0.0 39.8 24.7 5.8 28.0 67.7 132.8 82.4 37.6 0.7 43.9 31.5 TMEM243 "C7orf23, MGC4175, MM-TRAG" ENSG00000135185 "Transmembrane protein 243" Q9BU79 7 87196160-87220587 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 192.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 150.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014918 Uncertain NA Yes "Cluster 30: Non-specific - Translation" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA014918: AB_2067447" "unprognostic (5.14e-3)" "unprognostic (7.27e-2)" "unprognostic (1.36e-1)" "unprognostic (3.22e-2)" "unprognostic (2.59e-2)" "unprognostic (1.50e-1)" "unprognostic (3.39e-2)" "prognostic favorable (5.45e-4)" "prognostic unfavorable (6.84e-4)" "unprognostic (4.58e-2)" "unprognostic (2.69e-1)" "unprognostic (6.43e-2)" "unprognostic (1.16e-1)" "unprognostic (2.11e-2)" "unprognostic (1.41e-1)" "unprognostic (2.32e-2)" "prognostic favorable (9.13e-4)" 28.6 16.4 16.3 31.0 17.0 28.5 26.7 16.8 20.1 31.9 20.2 19.3 24.8 21.9 38.7 18.2 27.9 22.6 16.2 16.2 16.5 36.6 8.6 52.6 68.1 16.9 16.8 35.4 35.1 20.3 22.4 32.6 16.7 24.9 17.3 5.8 32.0 24.1 5.2 21.0 38.8 16.0 17.8 44.2 27.4 10.9 17.3 27.4 69.8 8.1 80.3 23.0 27.1 18.1 35.7 21.1 20.7 25.8 48.5 54.0 49.7 28.5 42.9 20.9 38.2 29.7 42.1 76.1 61.1 28.7 37.9 33.4 19.8 28.6 27.7 32.5 52.7 1.2 38.5 63.2 38.0 27.7 5.7 36.0 28.3 16.1 32.2 40.0 31.6 39.3 3.6 39.8 28.7 58.7 34.9 4.5 23.4 4.1 28.9 68.0 62.0 105.1 61.0 27.3 22.7 20.4 21.2 43.4 33.0 35.7 16.2 4.9 17.0 35.2 30.9 90.2 25.1 56.1 52.2 150.0 32.2 25.3 21.0 53.3 34.8 23.9 45.3 38.3 65.6 181.9 81.6 57.4 61.5 170.8 135.6 95.5 15.7 67.7 25.6 129.4 79.7 38.8 16.3 17.0 16.8 20.1 16.2 16.5 16.9 16.8 16.7 17.8 17.3 18.1 45.0 25.6 109.4 6.5 192.9 42.7 44.0 55.7 31.9 6.1 40.0 42.4 1.0 34.3 32.9 22.0 39.6 111.8 102.2 8.1 52.8 26.2 139.6 41.6 21.3 41.6 7.3 13.9 14.8 42.5 43.8 44.7 21.9 18.9 2.5 25.6 32.9 3.4 48.9 11.8 13.9 23.5 14.2 66.5 62.4 23.0 83.0 45.6 51.6 22.5 43.7 8.8 50.4 6.6 6.1 24.3 24.5 59.0 144.9 51.4 34.6 70.0 34.6 12.2 46.0 24.6 19.8 16.8 43.2 23.6 38.1 33.5 85.1 29.3 39.7 43.7 TMEM70 FLJ20533 ENSG00000175606 "Transmembrane protein 70" Q9BUB7 8 73972437-73982783 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "skeletal muscle: 100.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 78.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023187, CAB034226" Approved Supported Nucleoplasm,Mitochondria NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Mitochondria Nucleoplasm "CAB034226: AB_2205189, HPA023187: AB_2671101" "unprognostic (2.26e-3)" "unprognostic (4.87e-1)" "unprognostic (1.38e-2)" "unprognostic (1.11e-2)" "unprognostic (1.51e-3)" "unprognostic (8.22e-3)" "unprognostic (9.17e-2)" "unprognostic (1.01e-1)" "unprognostic (7.37e-2)" "unprognostic (7.04e-2)" "unprognostic (2.88e-2)" "unprognostic (9.14e-2)" "unprognostic (3.65e-3)" "unprognostic (6.86e-2)" "unprognostic (5.08e-2)" "unprognostic (2.13e-1)" "unprognostic (2.70e-2)" 18.1 18.2 9.2 9.8 9.7 10.4 11.3 10.5 12.3 8.0 9.5 12.6 5.8 8.9 10.6 9.3 11.3 8.9 19.3 10.3 10.2 12.0 24.4 9.0 10.1 9.6 9.1 10.5 25.0 8.3 7.6 10.3 10.1 7.4 9.7 6.1 9.9 5.9 100.7 7.7 9.5 9.1 9.5 9.6 17.8 9.8 9.5 11.0 6.0 20.5 10.3 11.3 7.4 10.1 21.2 16.4 13.1 13.8 14.9 12.7 13.6 17.6 15.8 19.4 15.3 15.8 11.9 28.4 15.0 12.0 16.4 19.1 24.9 16.8 21.4 18.9 17.5 28.3 10.0 21.2 14.7 15.5 14.5 11.8 15.3 12.2 6.4 7.3 16.4 14.2 22.0 13.5 20.5 15.9 35.8 29.6 12.3 26.6 20.6 25.4 12.8 24.2 20.5 20.0 29.7 13.1 11.0 78.0 23.3 10.2 16.0 14.1 10.6 11.1 13.7 20.7 16.9 19.9 18.7 28.1 16.4 12.1 12.5 6.3 9.1 6.7 8.0 10.2 9.1 17.7 9.0 9.3 9.6 10.9 10.3 9.6 6.7 5.8 7.9 11.0 7.9 12.0 9.2 9.7 10.5 12.3 10.3 10.2 9.6 9.1 10.1 9.5 9.5 10.1 136.2 16.0 30.1 5.5 37.1 67.3 43.7 54.8 24.5 23.9 26.2 22.2 46.3 14.3 35.7 22.0 8.4 71.2 48.1 69.0 66.5 36.6 20.3 40.8 26.2 96.4 13.8 26.5 12.8 63.5 59.6 50.2 17.3 17.1 39.9 17.0 28.5 50.3 132.4 10.1 11.4 31.7 42.7 70.0 74.5 12.1 29.8 73.2 40.9 5.6 38.9 23.1 22.6 3.5 8.1 43.6 37.9 29.0 68.6 42.1 28.8 75.4 58.7 17.5 39.5 61.9 40.8 70.6 29.5 21.5 59.7 70.3 39.8 52.6 34.1 26.2 TNFAIP8L1 MGC17791 ENSG00000185361 "TNF alpha induced protein 8 like 1" Q8WVP5 19 4639516-4655568 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 31.3;liver: 34.2" "Group enriched" "Detected in many" 5 "Early spermatids: 327.0;Late spermatids: 862.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 33.9;HUVEC TERT2: 33.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (1.39e-1)" "unprognostic (1.14e-2)" "unprognostic (3.70e-1)" "unprognostic (9.03e-3)" "unprognostic (1.00e-1)" "unprognostic (2.80e-2)" "unprognostic (8.39e-2)" "unprognostic (3.88e-2)" "unprognostic (1.82e-1)" "unprognostic (4.70e-2)" "unprognostic (3.70e-2)" "unprognostic (3.25e-2)" "prognostic unfavorable (1.28e-7)" "unprognostic (7.65e-2)" "unprognostic (8.99e-2)" "unprognostic (2.30e-1)" "unprognostic (3.22e-1)" 6.8 3.1 8.6 5.0 10.3 2.4 5.3 7.9 9.9 4.9 4.6 31.3 8.8 4.3 3.3 5.7 23.1 3.6 8.1 10.1 6.9 8.8 34.2 8.2 6.8 5.7 6.3 3.9 2.6 1.3 4.4 5.2 5.8 3.5 4.4 0.5 2.3 1.5 4.8 6.8 12.5 5.5 4.9 17.5 10.8 13.9 8.1 4.7 5.4 5.6 5.4 7.0 4.5 7.8 17.2 5.4 7.3 11.6 2.2 3.5 3.8 3.1 5.7 6.3 5.7 9.6 6.3 8.2 1.5 4.8 6.8 8.5 4.6 5.5 5.9 13.6 2.1 18.8 3.3 17.6 3.2 2.8 33.9 4.5 1.6 5.7 3.7 7.9 33.1 10.0 10.0 11.8 7.3 5.5 3.4 13.8 3.7 12.0 7.3 9.4 4.7 3.8 6.3 1.5 2.9 6.5 1.5 4.4 6.4 5.4 3.1 7.4 24.1 3.2 12.9 4.9 12.3 6.4 8.4 7.3 6.2 8.6 9.3 3.2 2.3 7.0 1.4 3.3 2.5 3.6 2.5 1.5 1.9 2.6 3.1 2.7 1.0 3.1 5.1 1.6 3.3 2.0 8.6 10.3 7.9 9.9 10.1 6.9 5.7 6.3 5.8 4.9 8.1 7.8 25.8 0.0 10.3 0.7 12.0 11.6 3.2 7.1 2.8 3.5 3.7 3.4 2.6 8.6 10.0 3.7 0.0 3.8 10.0 4.5 1.9 2.9 327.0 96.9 6.3 46.2 7.7 11.0 5.3 1.2 7.4 5.6 1.1 5.7 49.5 7.1 63.5 41.0 7.7 3.3 2.8 4.3 10.2 11.3 19.3 862.9 8.4 12.5 5.4 6.5 13.5 0.9 11.3 1.0 1.0 2.7 1.4 7.2 6.5 3.4 6.9 20.5 109.9 4.6 19.7 8.3 8.1 10.4 7.6 5.0 11.2 9.3 10.4 5.8 11.4 2.6 TNS2 "C1-TEN, KIAA1075, TENC1" ENSG00000111077 "Tensin 2" Q63HR2 12 53046969-53064379 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 109.3;Hepatic stellate cells: 93.1;Leydig cells: 141.7;Peritubular cells: 114.0;Sertoli cells: 151.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 114.2;ASC TERT1: 78.1;HHSteC: 59.9;HSkMC: 86.2;hTERT-RPE1: 61.9;TIME: 52.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034659 Approved NA Yes "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA034659: AB_10603349" "unprognostic (1.04e-1)" "unprognostic (2.58e-1)" "unprognostic (5.21e-3)" "unprognostic (1.86e-1)" "unprognostic (3.59e-2)" "unprognostic (7.26e-2)" "unprognostic (6.29e-2)" "unprognostic (5.42e-2)" "unprognostic (1.48e-2)" "unprognostic (8.97e-3)" "prognostic favorable (1.72e-4)" "prognostic favorable (9.32e-4)" "unprognostic (4.46e-2)" "unprognostic (1.09e-2)" "unprognostic (8.46e-2)" "unprognostic (1.47e-1)" "unprognostic (2.76e-2)" 156.3 66.9 59.3 14.8 66.2 0.3 121.6 46.4 57.8 121.2 33.3 79.0 14.4 98.8 14.0 28.3 121.0 32.5 99.6 43.7 49.2 67.3 66.5 83.4 15.8 58.0 63.5 104.1 34.6 17.0 43.3 33.1 54.0 66.3 11.5 6.0 35.7 41.1 69.0 42.1 56.7 28.5 50.8 79.5 58.2 15.9 58.3 7.2 80.6 58.8 6.4 82.6 81.1 57.9 2.0 21.2 2.7 2.2 114.2 78.1 0.7 11.8 27.1 6.2 3.2 1.4 5.7 0.1 25.3 32.1 2.6 1.5 0.1 7.8 2.4 0.5 0.8 0.4 25.5 11.3 59.9 0.3 0.5 86.2 0.3 7.9 4.7 61.9 36.3 0.4 0.6 0.3 24.9 5.1 0.2 0.4 1.9 1.4 5.8 0.7 6.6 0.3 8.2 0.4 1.2 2.7 4.4 2.4 8.8 1.6 26.1 0.7 52.1 12.9 14.8 4.7 2.0 0.6 0.3 0.1 20.4 0.3 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.3 66.2 46.4 57.8 43.7 49.2 58.0 63.5 54.0 50.8 58.3 57.9 109.3 3.2 25.7 33.3 0.5 0.0 6.8 0.0 5.2 21.1 15.1 13.0 7.9 10.0 2.5 5.5 0.0 0.5 0.9 0.4 3.9 5.8 2.8 4.4 41.1 69.6 1.2 2.7 3.1 4.4 0.4 40.5 2.0 14.5 0.0 7.7 93.1 37.5 2.4 30.3 7.8 3.9 0.0 4.4 0.0 7.2 141.7 2.9 0.0 31.9 0.1 29.6 0.0 46.3 35.6 2.4 9.0 114.0 1.8 4.5 2.1 2.6 1.5 11.3 151.2 51.3 64.7 4.2 4.4 1.3 0.0 0.8 1.4 2.6 1.8 2.1 TOB1 "APRO5, TOB, TROB, TROB1" ENSG00000141232 "Transducer of ERBB2, 1" P50616 17 50862223-50867978 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "T-47d: 253.3" "Low region specificity" "Detected in all" HPA047839 Approved Approved Nucleoplasm,Vesicles NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Vesicles "HPA047839: AB_2680175" "unprognostic (3.46e-1)" "unprognostic (1.09e-1)" "unprognostic (2.45e-1)" "unprognostic (6.78e-3)" "unprognostic (1.19e-1)" "unprognostic (8.27e-2)" "unprognostic (3.50e-3)" "unprognostic (1.53e-1)" "unprognostic (3.56e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (5.04e-5)" "prognostic unfavorable (3.37e-4)" "unprognostic (3.92e-3)" "unprognostic (9.44e-2)" "unprognostic (1.09e-1)" "unprognostic (4.13e-2)" "unprognostic (6.97e-2)" 42.6 210.2 32.6 22.3 34.9 70.2 65.3 31.6 40.8 55.3 59.3 47.4 56.1 23.9 26.5 77.7 54.6 47.6 44.7 29.8 39.4 67.9 168.6 36.8 18.9 37.3 48.2 63.4 207.9 81.4 50.1 13.8 38.6 72.3 57.5 101.8 99.8 92.2 178.6 133.5 48.1 29.4 31.8 17.8 87.5 26.0 33.4 17.7 95.4 109.9 21.0 81.9 70.9 40.2 44.1 88.7 28.1 11.5 51.4 25.4 22.0 31.9 79.2 20.5 25.0 36.0 54.6 40.0 60.6 43.9 20.7 61.0 19.5 54.1 21.1 20.4 29.3 4.8 100.7 60.5 72.0 21.5 18.9 54.5 65.5 23.9 120.0 27.3 9.9 12.2 17.0 33.7 43.4 119.0 16.1 19.4 10.2 109.4 33.9 14.0 35.6 47.6 80.9 89.4 16.6 40.4 55.1 158.9 19.9 42.5 253.3 27.1 13.2 23.3 16.7 26.7 15.8 51.9 57.7 18.5 19.2 10.2 9.1 417.7 53.5 285.6 245.8 107.3 269.9 40.7 222.7 192.5 119.1 31.9 192.1 233.6 130.7 28.8 152.5 38.5 206.0 169.0 32.6 34.9 31.6 40.8 29.8 39.4 37.3 48.2 38.6 31.8 33.4 40.2 101.6 115.4 118.3 71.8 53.1 283.2 232.9 119.8 284.0 125.3 180.6 179.6 115.5 210.1 81.8 68.0 56.3 20.8 124.8 183.3 103.7 42.6 97.9 143.7 51.7 40.7 203.4 18.1 11.5 54.1 2.0 83.5 123.3 176.2 63.9 19.7 33.2 205.6 35.4 18.5 14.1 223.2 48.8 27.6 249.2 40.4 26.4 89.9 71.2 5.6 29.1 118.3 20.6 16.6 34.1 41.8 186.7 59.8 41.3 187.2 126.2 60.4 87.8 62.7 164.3 137.3 123.8 36.9 12.1 153.8 230.7 10.9 154.7 77.4 167.6 287.2 TOB2 "APRO5, bK223H9, TOB4, TOBL, TROB2" ENSG00000183864 "Transducer of ERBB2, 2" Q14106 22 41433494-41446801 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016603, HPA054112" Approved Approved Cytosol NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 54: Non-specific - Microtubule organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA016603: AB_2669400, HPA054112: AB_2682385" "unprognostic (1.21e-3)" "unprognostic (3.10e-2)" "unprognostic (3.41e-1)" "prognostic favorable (3.08e-5)" "unprognostic (3.89e-2)" "unprognostic (1.38e-1)" "unprognostic (1.36e-1)" "unprognostic (5.36e-2)" "unprognostic (4.94e-2)" "unprognostic (5.74e-2)" "unprognostic (3.18e-2)" "unprognostic (1.17e-1)" "prognostic favorable (1.18e-6)" "unprognostic (1.50e-2)" "unprognostic (7.14e-2)" "unprognostic (1.85e-1)" "unprognostic (7.13e-2)" 46.1 31.3 39.3 15.6 56.3 9.7 25.5 78.1 40.1 26.5 18.5 30.1 22.4 25.0 11.8 26.6 38.4 28.8 41.2 39.3 43.8 24.6 27.1 20.7 18.5 61.7 42.9 38.0 29.0 35.6 22.8 22.0 44.0 26.6 15.5 55.0 17.2 19.4 86.5 27.1 23.9 20.1 39.5 20.6 30.5 13.6 52.0 19.6 36.1 68.1 19.7 23.3 21.0 71.9 36.8 16.6 28.5 19.4 65.4 45.5 27.5 23.9 36.7 29.8 26.2 21.9 17.0 22.4 23.5 34.8 11.6 31.4 26.7 13.4 27.1 23.0 34.2 12.3 23.9 33.4 44.8 33.5 15.9 42.1 22.5 35.6 15.4 30.1 30.2 7.6 18.9 24.5 24.6 40.8 13.9 19.2 24.4 48.1 17.6 29.7 19.2 19.4 21.3 25.3 13.1 8.8 60.0 32.2 44.6 17.7 17.9 16.5 37.9 29.3 27.1 23.0 22.7 22.9 10.7 12.2 17.8 14.2 19.7 3.9 5.9 4.1 7.5 8.0 7.1 10.0 6.2 6.3 5.3 7.5 3.2 4.7 3.8 3.8 8.4 8.0 5.5 6.1 39.3 56.3 78.1 40.1 39.3 43.8 61.7 42.9 44.0 39.5 52.0 71.9 48.5 48.1 59.6 48.6 61.4 126.8 66.6 24.3 105.3 56.0 83.1 56.9 59.8 58.6 31.7 47.8 64.6 34.7 56.9 76.9 23.5 29.7 41.1 88.6 59.3 45.3 54.3 16.8 12.2 19.1 37.3 54.1 42.3 116.9 34.1 13.7 52.5 29.7 19.6 25.2 15.1 67.7 10.2 22.0 117.9 61.6 66.8 51.4 53.4 14.0 34.6 58.3 18.6 10.1 43.6 32.3 60.0 82.0 26.2 73.6 103.6 29.2 45.9 105.2 52.6 97.4 60.9 23.8 28.9 88.7 136.7 63.3 57.4 19.6 61.9 92.2 TONSL "IKBR, NFKBIL2" ENSG00000160949 "Tonsoku like, DNA repair protein" Q96HA7 8 144428775-144444440 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.5" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 76.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA024679, HPA046494" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Nuclear bodies" "HPA024679: AB_1854441, HPA046494: AB_2679673" "unprognostic (6.68e-2)" "unprognostic (1.74e-1)" "unprognostic (2.40e-1)" "unprognostic (2.88e-2)" "unprognostic (7.35e-2)" "unprognostic (2.10e-3)" "prognostic unfavorable (2.84e-4)" "unprognostic (1.04e-3)" "unprognostic (7.81e-2)" "unprognostic (4.39e-2)" "unprognostic (3.38e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (2.62e-7)" "unprognostic (3.24e-2)" "unprognostic (1.78e-1)" "unprognostic (9.11e-3)" "unprognostic (7.96e-2)" 1.0 2.1 0.4 2.5 0.4 8.5 1.3 0.4 1.3 1.7 0.0 3.4 3.5 1.6 0.2 3.9 1.4 0.6 1.4 0.3 0.3 1.4 1.7 1.3 2.3 1.3 0.6 1.7 1.5 0.4 0.9 1.5 1.1 1.6 0.8 0.1 1.5 0.8 0.5 3.3 4.4 0.6 0.1 3.9 2.2 3.8 0.8 2.3 2.4 0.1 1.4 2.3 2.1 0.3 21.2 18.6 13.7 21.7 1.0 1.7 33.0 17.6 3.4 10.4 8.1 15.0 17.9 19.6 17.5 2.7 4.9 14.2 13.4 10.7 2.3 20.2 26.6 46.5 26.1 15.9 0.6 14.3 28.1 1.7 1.5 10.9 2.1 2.6 5.0 26.5 53.0 14.3 4.2 43.4 35.5 24.5 19.4 20.4 26.7 42.6 8.9 20.3 5.9 22.6 22.9 13.0 18.4 12.3 7.8 5.2 17.6 13.2 5.9 12.7 52.3 14.5 21.7 5.0 9.9 12.0 12.3 30.2 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.4 0.4 1.3 0.3 0.3 1.3 0.6 1.1 0.1 0.8 0.3 2.5 6.4 22.4 1.6 2.9 8.9 5.2 1.0 1.2 3.1 3.5 2.9 2.3 8.6 3.7 1.8 2.1 4.1 1.3 20.2 0.0 0.9 0.4 4.3 2.7 4.3 2.4 7.2 2.4 1.0 5.3 3.8 11.7 6.1 2.5 8.5 2.9 11.4 4.5 1.7 1.0 14.6 0.0 0.9 16.7 0.7 0.3 3.0 14.2 1.9 1.2 1.1 1.0 0.5 0.8 1.2 7.1 1.2 4.0 3.9 76.5 7.7 4.1 3.0 6.6 6.4 2.8 4.6 7.8 3.4 11.2 1.2 3.1 3.3 15.9 3.9 TOP1 ENSG00000198900 "DNA topoisomerase I" P11387 20 41028822-41124487 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 801.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009058, HPA019039" Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center" No Yes 7600 "Cluster 31: Non-specific - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 36: HEL - Hemostasis" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Nucleoli fibrillar center" "CAB009058: AB_2303554, HPA019039: AB_1858187" "unprognostic (1.46e-1)" "unprognostic (8.65e-2)" "unprognostic (1.33e-2)" "unprognostic (1.92e-3)" "unprognostic (5.05e-2)" "unprognostic (1.49e-3)" "prognostic unfavorable (6.42e-4)" "unprognostic (5.86e-2)" "unprognostic (1.51e-1)" "unprognostic (4.60e-2)" "unprognostic (3.74e-3)" "unprognostic (6.51e-2)" "unprognostic (8.65e-2)" "unprognostic (4.70e-2)" "unprognostic (5.14e-1)" "unprognostic (3.64e-1)" "unprognostic (1.29e-1)" 37.9 36.7 17.4 49.9 18.6 74.9 27.9 21.8 25.1 26.9 25.3 36.9 42.6 27.9 34.4 36.7 22.4 37.2 19.1 18.0 18.9 39.0 47.5 40.0 59.9 18.5 18.4 24.3 28.6 26.7 22.4 50.2 18.1 31.8 37.3 25.5 26.7 24.2 21.3 26.5 42.6 23.9 18.7 38.5 36.5 18.9 18.8 58.9 37.6 20.2 60.6 42.7 28.8 19.2 105.2 71.7 131.4 108.2 52.2 61.8 129.8 92.6 81.0 105.0 94.8 190.5 127.6 296.4 96.4 48.5 112.3 98.9 159.1 147.2 153.0 64.9 81.6 378.6 54.9 139.0 135.4 165.1 124.0 69.8 76.4 102.4 166.8 94.0 111.5 98.1 167.8 98.7 120.9 233.2 235.3 119.7 106.3 104.1 131.6 197.7 123.1 157.7 121.4 95.2 108.6 75.4 145.4 88.3 95.0 94.2 98.6 146.4 109.9 84.7 71.3 78.8 100.9 62.7 75.6 338.3 113.7 91.1 82.0 12.6 9.9 16.8 6.6 10.3 8.3 10.5 7.3 7.0 9.5 10.1 7.7 6.9 19.1 6.3 13.2 18.8 9.0 5.4 17.4 18.6 21.8 25.1 18.0 18.9 18.5 18.4 18.1 18.7 18.8 19.2 116.9 118.6 201.5 66.0 117.6 245.9 338.0 90.3 153.7 98.2 90.5 75.7 49.7 78.6 170.3 99.3 60.5 192.1 137.1 194.1 74.3 94.4 10.0 151.3 167.4 115.1 91.8 486.5 86.9 65.8 175.4 121.4 84.1 259.2 78.6 119.1 67.1 131.7 99.2 72.3 77.4 126.9 69.2 101.2 109.1 12.8 59.7 151.6 72.9 74.9 95.4 88.0 78.2 87.4 90.7 119.2 169.8 69.6 234.1 162.3 94.1 136.2 68.3 87.0 85.5 135.5 130.8 116.8 54.6 129.4 214.2 801.5 111.5 123.7 117.8 237.7 TOR3A "ADIR, ADIR2, FLJ22345" ENSG00000186283 "Torsin family 3 member A" Q9H497 1 179082070-179098023 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 112.6;Plasma cells: 153.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 281.7;U-266/84: 322.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028766 Approved "Intracellular and membrane" NA Yes 24000 "Cluster 19: B-cells - Humoral immune response" "Cluster 52: Non-specific - Ribosome" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA028766: AB_10602251" "unprognostic (5.55e-2)" "unprognostic (6.52e-2)" "unprognostic (2.80e-1)" "unprognostic (1.59e-2)" "unprognostic (1.10e-1)" "unprognostic (3.90e-1)" "unprognostic (8.82e-3)" "unprognostic (6.47e-2)" "unprognostic (2.02e-2)" "unprognostic (4.87e-2)" "unprognostic (2.27e-1)" "unprognostic (3.99e-1)" "prognostic unfavorable (4.78e-8)" "unprognostic (4.26e-2)" "unprognostic (2.27e-1)" "unprognostic (3.58e-1)" "unprognostic (1.35e-1)" 17.0 15.5 16.9 30.8 17.9 39.7 19.5 16.4 18.6 16.7 19.3 26.1 23.3 16.1 12.8 15.8 17.8 18.1 12.8 17.2 19.4 17.0 27.8 20.4 46.4 18.3 17.2 14.8 23.4 22.5 16.9 15.3 17.2 17.9 26.0 9.5 23.9 17.0 24.4 17.8 23.1 18.8 17.6 37.4 26.5 4.3 19.9 26.7 18.6 13.9 44.8 23.3 13.5 19.3 56.8 65.5 18.6 52.6 38.2 29.9 57.1 41.4 50.0 48.0 34.8 29.8 86.4 90.0 70.2 41.1 28.9 68.5 53.7 34.6 25.3 70.8 49.4 98.3 38.5 45.9 62.9 109.6 80.6 33.1 31.0 35.3 31.9 19.2 35.5 34.8 123.9 164.3 33.8 121.4 66.3 60.5 38.6 68.0 36.4 49.4 33.9 88.4 30.5 76.8 37.8 49.3 61.9 96.9 25.5 32.5 71.5 80.1 22.0 36.2 25.6 59.9 54.3 281.7 322.8 77.4 25.1 77.3 26.5 5.2 71.3 19.3 33.6 56.5 41.4 97.8 29.9 37.7 85.7 73.1 22.7 27.6 14.1 31.5 59.4 93.1 43.3 53.3 16.9 17.9 16.4 18.6 17.2 19.4 18.3 17.2 17.2 17.6 19.9 19.3 24.8 3.2 11.7 4.9 65.2 17.0 14.0 19.2 10.8 3.7 14.8 11.3 11.5 25.8 11.1 11.0 10.4 30.1 32.5 18.6 3.9 34.0 1.1 10.6 16.8 19.3 14.4 18.3 4.4 44.5 57.5 19.8 20.9 11.1 10.8 14.3 13.9 10.7 57.4 0.0 4.6 18.9 32.6 22.0 112.6 1.1 17.1 36.4 16.0 5.6 50.6 17.1 16.5 3.0 4.0 18.9 17.9 18.8 153.7 19.5 15.1 10.3 13.4 9.6 6.6 18.9 17.3 0.8 5.3 12.7 15.8 10.9 24.8 21.2 27.0 12.3 TP73 P73 ENSG00000078900 "Tumor protein p73" O15350 1 3652516-3736201 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 8.0;fallopian tube: 6.7;skin 1: 6.6" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 13.0;Basal squamous epithelial cells: 16.5;Early spermatids: 21.8;Endometrial ciliated cells: 31.0;Late spermatids: 15.7;Respiratory ciliated cells: 35.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MOLT-4: 15.0;RH-30: 11.6;SCLC-21H: 18.0;U-698: 18.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB002514, CAB003022, HPA027314, HPA044516" Enhanced Supported "Nucleoplasm,Golgi apparatus" NA Yes "Cluster 27: Brain & Skin - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Golgi apparatus" "CAB002514: AB_563940, CAB003022: , HPA027314: AB_2672215, HPA044516: AB_2678971" "unprognostic (5.71e-3)" "prognostic favorable (2.98e-4)" "unprognostic (2.71e-1)" "prognostic favorable (1.82e-4)" "unprognostic (5.58e-2)" "prognostic favorable (9.50e-4)" "unprognostic (5.25e-2)" "unprognostic (2.18e-1)" "unprognostic (4.27e-1)" "unprognostic (1.99e-1)" "unprognostic (5.33e-2)" "unprognostic (3.99e-1)" "unprognostic (1.26e-7)" "unprognostic (1.77e-2)" "unprognostic (1.10e-1)" "unprognostic (7.33e-2)" "unprognostic (1.65e-1)" 0.0 0.0 0.7 0.7 0.5 0.5 0.8 4.2 0.5 1.4 8.0 0.2 0.0 0.1 0.1 3.7 6.7 0.0 0.1 0.8 0.7 0.1 0.2 0.9 1.0 2.4 2.9 0.1 0.8 0.1 0.3 0.0 1.4 2.6 0.1 0.2 2.9 0.3 0.2 6.6 0.2 0.0 1.4 0.7 0.3 0.7 0.7 1.6 0.2 0.0 1.4 0.1 2.9 1.0 2.6 0.1 0.3 7.8 0.0 0.0 0.6 0.0 0.0 0.0 0.0 10.9 4.0 2.6 2.0 0.0 0.9 4.3 2.7 0.9 0.0 0.8 8.7 0.2 3.9 2.6 0.0 0.0 2.9 0.0 1.7 0.0 0.1 0.0 0.0 0.0 5.6 0.0 0.8 1.9 15.0 2.0 0.5 0.0 0.1 0.0 11.6 0.1 0.3 3.8 18.0 8.4 0.4 0.0 0.8 0.0 10.9 9.2 0.0 2.9 7.5 0.0 5.8 3.3 0.7 18.5 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.5 4.2 0.5 0.8 0.7 2.4 2.9 1.4 1.4 0.7 1.0 0.0 0.0 1.5 0.0 1.2 3.1 3.8 13.0 16.5 0.5 0.2 2.5 1.5 0.0 7.4 0.0 0.0 0.2 0.0 0.5 0.0 0.0 21.8 31.0 0.3 0.3 2.4 3.2 0.1 0.2 0.4 0.4 0.0 0.7 0.0 0.1 0.4 0.2 0.3 0.0 0.1 0.5 2.0 0.0 1.3 15.7 0.6 0.1 1.8 0.0 0.0 0.2 0.0 2.5 0.1 0.2 0.0 0.0 6.8 0.2 0.0 0.1 35.8 0.1 0.0 0.0 2.6 0.1 0.4 1.6 2.3 0.3 0.4 0.1 0.3 0.2 TSPYL4 "dJ486I3.2, KIAA0721" ENSG00000187189 "TSPY like 4" Q9UJ04 6 116249964-116254075 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 109.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA044863 Approved NA Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "HPA044863: AB_10962578" "unprognostic (5.10e-2)" "unprognostic (2.05e-1)" "unprognostic (1.79e-1)" "unprognostic (1.65e-3)" "unprognostic (1.67e-1)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (1.80e-2)" "unprognostic (3.34e-1)" "unprognostic (7.41e-3)" "prognostic favorable (8.46e-5)" "unprognostic (1.30e-1)" "prognostic favorable (5.13e-7)" "unprognostic (3.34e-3)" "unprognostic (2.57e-1)" "unprognostic (3.61e-1)" "unprognostic (5.38e-2)" 8.2 35.4 57.5 7.5 61.8 10.4 14.0 56.2 109.7 17.1 15.5 12.3 5.8 21.5 18.0 11.6 21.0 10.6 20.4 62.8 72.8 14.9 9.0 10.2 10.3 44.9 55.9 25.4 12.2 28.7 28.4 10.7 60.0 22.4 8.1 30.1 9.6 18.5 5.1 10.5 9.3 15.4 43.1 11.0 15.3 14.8 69.5 17.7 14.3 7.8 9.2 11.8 11.9 48.5 6.2 3.4 47.6 39.7 19.2 16.4 8.9 24.3 16.4 30.6 18.2 9.6 5.9 5.0 9.0 37.5 16.1 13.6 20.7 21.6 45.8 20.7 7.0 10.1 18.8 22.7 15.1 19.1 6.4 16.0 10.0 23.7 12.0 23.9 21.0 28.0 15.7 16.4 25.7 19.2 36.9 11.7 11.5 2.1 8.1 20.9 2.6 4.9 9.2 9.0 55.9 37.6 21.6 9.0 4.3 16.9 16.3 10.5 24.4 25.4 21.3 14.6 14.1 6.6 8.2 0.8 11.7 12.5 16.2 0.5 2.1 2.5 3.2 1.8 3.8 2.4 3.9 3.3 1.9 3.0 4.1 3.1 2.8 3.8 2.8 3.1 3.6 4.0 57.5 61.8 56.2 109.7 62.8 72.8 44.9 55.9 60.0 43.1 69.5 48.5 7.0 3.2 7.7 11.8 9.2 4.8 11.9 4.9 30.1 21.4 11.8 13.2 44.2 11.5 7.2 11.0 20.9 3.3 13.0 3.2 19.6 5.4 20.3 30.8 31.9 11.5 31.7 6.1 16.2 7.4 2.0 13.3 8.6 25.8 11.4 27.5 11.7 3.7 3.6 40.4 16.8 5.8 6.1 6.8 3.5 6.7 10.2 8.8 5.4 7.5 5.9 20.7 6.2 4.5 8.5 7.1 2.5 10.9 7.3 7.0 0.7 6.4 27.5 28.7 0.0 14.8 16.8 20.1 3.6 14.1 5.3 3.4 11.9 18.9 4.5 8.0 TUBB4B "Beta2, TUBB2C" ENSG00000188229 "Tubulin beta 4B class IVb" P68371 9 137241287-137243707 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Deafness, Disease variant, FDA approved drug targets, Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 2190.0;Late spermatids: 2907.1;Spermatocytes: 1717.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010880, HPA043640, HPA046280" Enhanced Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 38: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB010880: AB_609915, HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (2.24e-1)" "unprognostic (1.77e-3)" "unprognostic (1.50e-1)" "prognostic favorable (4.91e-4)" "unprognostic (1.29e-2)" "unprognostic (8.93e-2)" "prognostic unfavorable (9.98e-4)" "unprognostic (9.92e-3)" "unprognostic (2.90e-1)" "unprognostic (3.63e-1)" "unprognostic (2.34e-1)" "unprognostic (4.09e-2)" "unprognostic (2.47e-3)" "unprognostic (6.37e-2)" "unprognostic (1.36e-2)" "prognostic favorable (6.36e-6)" "unprognostic (1.69e-1)" 134.5 112.6 162.0 97.2 163.4 423.9 94.4 149.4 182.7 88.1 482.7 198.3 142.0 107.7 209.1 343.3 507.2 106.0 435.8 174.0 185.2 122.5 140.1 130.5 95.5 184.1 233.6 72.9 123.8 87.8 118.0 86.3 213.9 120.2 111.9 261.8 177.9 121.5 202.5 240.0 166.4 119.8 162.9 85.6 161.4 765.7 192.6 162.9 115.7 96.6 119.7 188.3 139.4 133.9 706.2 1032.5 431.7 314.2 213.2 223.6 600.5 643.7 536.0 872.4 598.6 1101.0 840.2 429.0 480.2 631.2 848.2 1305.1 539.5 1039.2 330.2 307.9 458.5 311.2 789.6 877.8 134.5 370.0 331.5 145.0 291.5 667.5 183.1 215.7 631.7 300.6 443.0 239.7 731.2 1936.4 337.4 504.2 457.8 1234.8 1778.1 423.5 822.2 394.2 666.8 647.8 301.5 323.6 853.9 485.8 173.2 244.2 699.0 397.6 495.6 618.1 685.0 710.0 863.6 92.4 274.9 475.1 503.6 286.9 549.8 95.7 30.0 43.2 40.5 30.1 38.2 32.6 31.3 34.4 34.9 30.8 19.7 26.7 56.4 24.4 30.5 36.3 44.7 32.6 162.0 163.4 149.4 182.7 174.0 185.2 184.1 233.6 213.9 162.9 192.6 133.9 478.5 221.2 146.3 21.5 315.8 326.2 945.7 458.7 327.2 508.1 286.9 389.5 91.9 143.0 284.1 143.5 300.3 346.6 640.9 744.1 221.1 348.6 2190.0 1191.6 224.8 203.9 391.5 419.9 30.1 446.8 545.5 247.8 274.7 415.0 189.2 200.9 142.5 139.2 265.9 244.0 24.3 503.6 323.5 59.9 214.9 2907.1 254.2 299.3 138.7 22.5 224.0 299.3 49.4 15.6 19.7 477.4 697.2 153.1 264.0 475.1 540.7 345.5 1558.7 763.3 111.7 261.8 416.0 1717.5 740.9 419.1 297.6 321.1 362.9 89.8 487.3 592.7 TXNL1 "TRP32, Txl, TXNL" ENSG00000091164 "Thioredoxin like 1" O43396 18 56597209-56651600 "Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002828, HPA002829, CAB016446" Supported Supported Enhanced Cytosol NA Yes 1100000 "Cluster 34: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB016446: , HPA002828: AB_1858358, HPA002829: AB_1858359" "unprognostic (2.05e-1)" "unprognostic (2.97e-1)" "unprognostic (3.38e-3)" "unprognostic (4.54e-2)" "unprognostic (2.51e-1)" "unprognostic (1.78e-1)" "prognostic unfavorable (9.62e-6)" "unprognostic (1.83e-1)" "unprognostic (1.03e-2)" "prognostic favorable (6.26e-5)" "unprognostic (1.44e-1)" "unprognostic (2.79e-1)" "unprognostic (3.29e-3)" "unprognostic (1.24e-1)" "unprognostic (1.26e-1)" "unprognostic (2.62e-1)" "unprognostic (1.51e-1)" 38.3 55.9 45.4 38.6 47.5 83.0 49.1 49.1 63.6 42.5 40.1 41.7 42.1 38.3 66.9 54.2 35.2 40.0 80.0 50.0 50.9 51.7 80.7 30.6 41.2 47.7 47.2 47.1 62.2 51.4 38.2 48.1 49.5 40.5 43.4 77.9 48.5 39.3 149.0 36.5 40.6 43.4 46.2 32.2 46.7 41.9 47.5 48.0 197.9 146.8 49.9 51.8 35.1 54.0 77.7 74.8 99.2 102.8 83.2 121.6 70.2 90.2 91.8 113.4 95.4 67.0 74.2 83.4 78.1 98.4 82.3 93.7 94.4 81.3 116.9 85.7 43.1 114.9 58.3 127.1 98.3 168.9 71.7 92.9 82.4 107.4 97.4 118.8 93.0 62.9 85.5 136.0 116.0 74.4 98.1 109.8 71.9 53.5 79.6 78.2 66.8 145.9 133.0 118.6 81.6 74.5 51.3 70.9 88.1 78.3 77.5 89.1 74.3 118.7 62.9 41.9 89.5 130.8 151.1 130.5 77.2 127.0 89.1 98.5 63.1 48.3 26.9 55.8 37.2 38.9 33.0 35.8 54.8 35.4 32.0 32.9 48.3 43.3 54.9 47.0 42.9 61.5 45.4 47.5 49.1 63.6 50.0 50.9 47.7 47.2 49.5 46.2 47.5 54.0 89.7 57.7 45.9 25.5 80.0 134.3 123.1 177.1 75.7 82.7 89.3 110.4 110.1 67.2 108.3 29.5 139.7 242.3 82.7 72.2 109.5 150.5 246.9 88.0 90.0 84.2 75.9 153.8 43.8 128.3 130.9 86.1 52.0 90.3 53.2 167.5 52.8 78.0 150.1 57.2 43.6 111.6 77.3 97.3 97.0 294.1 77.6 90.5 65.8 15.9 121.8 86.0 78.2 26.2 55.6 139.5 83.7 83.8 88.9 121.2 110.0 144.7 75.1 97.1 65.7 73.0 167.1 204.1 108.0 93.9 126.0 358.6 72.4 171.0 109.7 123.1 TYMS "HsT422, TMS, TS, Tsase" ENSG00000176890 "Thymidylate synthetase" P04818 18 657653-673578 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Nucleotide biosynthesis" "Methyltransferase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 88.5;lymphoid tissue: 113.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 105.8;Erythroid cells: 189.3;Extravillous trophoblasts: 115.3;Plasma cells: 112.7;Spermatocytes: 180.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 14.1" "Group enriched" "Detected in many" 6 "NK-cells: 6.7;T-cells: 14.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB002784, HPA074922" Enhanced NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "CAB002784: , HPA074922: " "unprognostic (7.58e-2)" "unprognostic (2.06e-3)" "unprognostic (9.31e-2)" "unprognostic (2.34e-2)" "unprognostic (7.35e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (5.10e-6)" "unprognostic (1.62e-3)" "unprognostic (1.68e-2)" "unprognostic (9.82e-2)" "unprognostic (1.07e-3)" "unprognostic (3.28e-2)" "unprognostic (1.23e-2)" "unprognostic (6.34e-2)" "unprognostic (1.66e-1)" "unprognostic (5.65e-3)" "unprognostic (2.47e-1)" 4.5 3.1 4.3 24.2 7.5 88.5 6.7 4.1 6.5 4.8 2.7 22.9 10.5 5.1 1.3 14.8 5.6 3.8 2.2 5.0 4.9 6.5 11.8 4.9 36.1 4.9 5.2 2.1 3.6 1.8 1.6 22.3 4.4 3.1 27.1 4.2 3.9 2.0 0.4 6.2 14.8 12.7 4.8 10.6 8.8 34.3 6.1 113.6 2.1 0.4 44.5 8.4 5.5 10.3 102.7 156.6 320.4 154.9 35.1 57.9 159.9 238.9 141.1 251.7 299.9 132.8 80.1 160.0 91.5 129.9 143.2 45.1 225.3 89.7 216.1 152.3 244.9 273.1 135.8 229.4 8.2 564.8 286.5 51.5 20.7 159.6 49.6 48.4 214.4 334.0 222.0 249.6 321.8 118.1 687.7 311.4 114.7 124.3 114.0 446.8 287.0 191.3 95.6 88.9 106.0 175.7 201.4 91.6 61.1 197.3 63.5 253.5 85.0 289.7 569.5 267.3 474.2 305.9 405.2 367.3 75.2 240.6 339.2 0.0 0.0 1.3 1.1 0.1 0.0 1.1 2.8 2.2 1.8 0.0 0.0 0.6 0.7 6.7 0.1 0.3 14.1 2.9 4.3 7.5 4.1 6.5 5.0 4.9 4.9 5.2 4.4 4.8 6.1 10.3 2.1 0.0 2.3 1.6 15.7 14.4 15.9 13.0 27.9 0.5 7.8 11.7 3.6 2.8 6.7 0.0 0.0 105.8 14.5 15.5 1.9 2.3 34.4 5.6 8.4 12.5 1.2 189.3 0.4 0.8 115.3 28.3 14.3 7.4 7.0 76.2 6.8 4.3 71.4 0.0 0.6 20.9 10.2 15.6 19.4 31.9 6.2 10.7 10.6 1.0 3.9 45.0 5.2 0.5 15.6 1.5 8.9 3.8 112.7 5.0 13.8 36.6 1.0 2.4 13.1 1.3 32.6 180.8 30.7 48.0 7.2 27.0 21.3 10.5 54.9 18.7 UBE2S E2-EPF ENSG00000108106 "Ubiquitin conjugating enzyme E2 S" Q16763 19 55399745-55407788 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 115.9;testis: 158.3" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 341.4;dendritic cells: 432.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015228, HPA057150" Approved Approved "Nucleoplasm,Plasma membrane" NA Yes "Cluster 37: B-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" Nucleoplasm "CAB015228: , HPA057150: AB_2683351" "unprognostic (2.79e-1)" "unprognostic (2.42e-1)" "unprognostic (2.57e-1)" "prognostic unfavorable (2.05e-4)" "unprognostic (9.54e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (8.00e-6)" "unprognostic (1.42e-3)" "unprognostic (2.32e-1)" "unprognostic (2.31e-1)" "unprognostic (8.08e-2)" "unprognostic (4.52e-2)" "prognostic unfavorable (8.16e-8)" "unprognostic (1.05e-1)" "unprognostic (9.51e-2)" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" 16.3 17.6 17.1 21.8 17.3 115.9 11.0 15.7 23.7 16.8 10.9 18.5 11.4 17.2 5.5 37.1 15.1 13.1 24.8 25.2 23.8 13.0 11.5 16.2 35.7 17.0 16.5 14.8 7.7 6.8 28.8 13.6 22.2 15.1 9.3 9.4 12.0 6.2 15.5 12.0 16.2 15.0 16.7 25.7 17.6 158.3 18.9 47.8 10.3 5.7 30.9 16.2 17.8 21.3 532.9 279.4 241.3 193.8 15.3 21.6 42.9 419.3 126.1 253.2 229.1 191.1 183.6 508.6 169.5 106.4 304.5 152.9 243.6 109.5 111.4 402.0 810.5 305.8 162.8 62.5 45.1 370.0 286.0 23.8 30.2 186.7 179.1 55.0 100.6 272.7 310.0 347.0 161.3 139.5 503.2 191.3 605.3 147.2 470.6 437.4 185.5 185.8 69.2 111.5 609.3 330.0 534.5 131.2 248.6 72.6 93.8 198.1 155.9 151.9 432.8 130.7 1013.5 277.1 734.4 617.0 159.2 257.5 562.7 0.5 0.8 1.3 0.7 0.6 0.5 2.5 1.0 1.0 0.6 0.6 1.0 0.5 2.4 0.2 0.4 1.3 0.4 0.1 17.1 17.3 15.7 23.7 25.2 23.8 17.0 16.5 22.2 16.7 18.9 21.3 308.0 0.0 3.4 5.9 161.3 162.6 151.2 31.5 81.4 59.3 235.9 341.4 3.1 8.6 9.9 20.2 54.2 87.8 432.7 59.2 15.6 42.8 127.5 89.3 68.2 72.5 92.6 166.5 8.7 30.5 247.9 99.3 44.9 68.0 18.4 200.9 31.8 10.6 65.5 32.0 11.0 69.1 38.7 26.8 125.3 52.2 17.4 131.7 74.7 3.7 36.7 91.1 21.6 7.5 13.5 82.3 44.1 12.4 100.6 82.9 20.4 18.4 9.7 75.7 13.1 125.2 186.7 196.9 174.0 74.1 115.9 59.8 233.3 64.6 55.8 121.1 UHRF1 "FLJ21925, ICBP90, Np95, RNF106, TDRD22" ENSG00000276043 "Ubiquitin like with PHD and ring finger domains 1" Q96T88 19 4903080-4962154 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, DNA-binding, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 27.0;lymphoid tissue: 67.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 49.7;Plasma cells: 21.0;Squamous epithelial cells: 15.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.8" "Group enriched" "Detected in many" 4 "dendritic cells: 4.8;T-cells: 2.3" "Cell line enhanced" "Detected in all" "MOLT-4: 450.9;REH: 1004.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA049408, HPA055446" Enhanced Supported Nucleoplasm No Yes "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA049408: AB_2756317, HPA055446: AB_2732597" "unprognostic (3.83e-2)" "unprognostic (6.83e-3)" "unprognostic (5.13e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "unprognostic (7.21e-2)" "prognostic unfavorable (1.63e-4)" "unprognostic (4.30e-2)" "prognostic unfavorable (6.81e-4)" "unprognostic (2.82e-1)" "prognostic unfavorable (4.52e-5)" "unprognostic (2.33e-3)" "unprognostic (0.00e+0)" "unprognostic (3.75e-3)" "unprognostic (2.45e-1)" "unprognostic (2.01e-1)" "unprognostic (2.02e-1)" 1.0 0.9 2.1 9.6 2.7 27.0 1.7 2.1 2.3 1.6 1.8 2.9 3.7 1.0 0.1 6.5 0.4 0.8 0.5 2.0 2.2 0.6 0.9 1.3 15.8 2.8 2.8 0.3 0.6 0.2 0.2 2.1 2.7 0.6 2.6 0.4 1.5 0.2 1.2 3.4 3.9 1.9 1.9 3.7 3.3 5.2 3.5 67.2 0.3 0.3 10.3 1.6 2.5 4.6 111.3 78.7 116.6 83.4 3.3 13.3 18.5 88.3 42.0 89.9 86.8 94.6 54.9 62.7 21.1 39.4 32.7 54.1 81.2 47.7 63.0 102.7 92.2 54.3 74.3 102.4 1.3 135.1 78.9 6.5 3.5 48.9 12.6 14.1 27.2 97.2 79.3 70.5 54.5 86.7 450.9 82.5 52.5 40.0 84.3 1004.5 259.7 45.4 24.9 80.1 86.0 68.5 69.2 37.7 12.1 18.8 68.2 127.6 34.2 94.6 76.7 124.3 108.3 29.8 33.1 183.5 54.8 129.7 123.3 0.3 0.2 0.1 0.6 0.0 0.0 0.2 0.8 1.0 1.3 0.1 0.2 0.8 0.8 0.5 0.2 4.8 2.3 0.6 2.1 2.7 2.1 2.3 2.0 2.2 2.8 2.8 2.7 1.9 3.5 4.6 0.2 0.0 0.0 1.6 2.1 0.0 0.8 0.0 3.4 2.5 4.4 2.8 4.3 1.5 0.6 0.0 0.0 6.6 6.9 2.6 0.0 2.2 2.9 1.3 1.8 2.2 0.0 49.7 0.4 0.4 7.8 4.7 8.6 2.4 0.0 10.4 0.4 0.7 8.9 3.3 0.4 2.3 0.0 1.9 0.0 1.8 0.6 3.8 0.0 0.0 2.0 0.6 1.0 3.0 1.3 4.2 1.9 0.4 21.0 0.6 1.4 0.2 0.7 0.7 0.0 1.2 6.1 6.1 11.9 15.8 0.0 1.4 3.7 1.5 8.3 1.3 UNG "DGU, HIGM4, UDG, UNG1, UNG2" ENSG00000076248 "Uracil DNA glycosylase" P13051 12 109097597-109110992 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 64.9;Spermatogonia: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB011605 Uncertain Approved Cytosol NA Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "CAB011605: AB_778737" "unprognostic (4.38e-2)" "unprognostic (3.82e-3)" "unprognostic (1.03e-2)" "unprognostic (1.33e-2)" "unprognostic (4.64e-1)" "unprognostic (4.10e-2)" "prognostic unfavorable (6.40e-4)" "unprognostic (5.68e-3)" "prognostic unfavorable (3.06e-4)" "unprognostic (4.66e-2)" "unprognostic (8.78e-3)" "unprognostic (1.91e-1)" "unprognostic (1.35e-3)" "unprognostic (2.57e-2)" "unprognostic (4.50e-1)" "unprognostic (1.40e-2)" "unprognostic (6.89e-2)" 19.8 56.7 32.4 14.7 32.4 16.0 23.1 30.1 34.8 16.6 27.7 28.0 17.1 14.5 12.7 29.7 15.6 10.4 21.1 29.2 34.9 27.5 32.2 9.6 18.0 32.2 31.4 15.7 12.4 33.2 10.9 17.8 34.1 13.6 29.3 6.8 17.7 17.6 43.0 32.7 18.8 14.5 31.6 16.1 17.7 24.3 33.5 22.8 22.2 33.5 27.0 13.5 20.1 30.8 77.1 77.5 72.8 66.6 118.6 33.8 69.5 44.4 30.1 68.6 52.3 61.7 51.6 100.3 65.1 40.2 35.9 47.6 81.4 46.0 66.4 85.6 150.9 98.1 41.1 105.5 17.7 147.6 58.2 30.7 41.6 33.0 18.3 54.6 50.4 117.8 80.9 32.5 47.0 96.2 136.8 173.6 130.0 124.2 117.7 123.9 109.8 85.9 43.4 95.6 103.3 57.4 79.6 67.8 39.5 94.2 126.2 68.2 26.0 59.1 52.7 39.3 62.5 62.6 145.0 190.5 44.8 97.7 73.8 12.9 2.7 5.0 22.4 5.3 31.6 16.0 25.5 25.6 6.8 17.2 16.4 18.4 0.0 16.5 5.5 4.9 25.5 14.4 32.4 32.4 30.1 34.8 29.2 34.9 32.2 31.4 34.1 31.6 33.5 30.8 26.6 0.0 4.8 16.0 9.2 18.0 11.0 13.2 25.0 2.6 21.7 14.1 12.4 7.2 5.0 42.3 4.2 64.9 12.5 14.7 19.6 14.4 3.4 7.6 15.0 17.7 8.4 32.4 7.0 6.2 38.1 12.6 14.3 9.9 7.6 24.8 20.3 20.8 18.3 5.0 6.2 21.4 10.2 3.8 5.4 4.2 14.0 5.5 14.2 6.5 3.8 15.8 7.2 6.6 4.0 5.0 10.3 14.7 16.7 6.8 9.3 20.2 3.2 3.5 6.6 10.2 11.5 21.9 74.6 37.8 20.9 20.4 15.3 25.7 40.4 9.7 USP37 KIAA1594 ENSG00000135913 "Ubiquitin specific peptidase 37" Q86T82 2 218450251-218568351 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 119.4;Late spermatids: 145.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045160 Approved Approved Nucleoplasm,Nucleoli NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Nucleoli" "HPA045160: AB_10795620" "unprognostic (7.00e-2)" "unprognostic (2.29e-1)" "unprognostic (8.83e-2)" "unprognostic (9.19e-4)" "unprognostic (1.83e-1)" "prognostic favorable (2.85e-4)" "unprognostic (2.18e-2)" "unprognostic (1.14e-1)" "unprognostic (9.66e-3)" "unprognostic (1.17e-1)" "unprognostic (3.78e-3)" "unprognostic (1.11e-1)" "unprognostic (3.82e-2)" "unprognostic (3.26e-1)" "unprognostic (2.87e-1)" "unprognostic (6.69e-2)" "unprognostic (6.41e-3)" 2.7 4.1 3.5 4.4 4.7 11.8 4.7 8.5 4.9 3.6 1.9 3.0 2.9 4.2 7.5 3.9 3.3 3.5 2.3 3.3 4.0 2.9 3.8 3.0 6.0 3.8 4.0 5.9 3.0 4.0 1.4 4.0 4.0 3.6 3.5 9.1 3.9 3.0 2.9 3.9 3.3 3.2 2.5 3.8 3.4 12.7 3.4 6.3 5.0 4.2 4.9 3.6 2.2 8.3 9.6 6.9 14.2 11.0 3.6 4.4 12.1 7.1 5.1 12.2 13.6 13.1 7.4 8.7 7.5 5.6 9.3 8.9 15.7 8.0 13.4 12.0 8.3 23.5 13.6 8.7 4.1 15.6 11.3 2.4 4.7 12.9 9.2 4.5 5.3 15.0 17.3 16.2 7.8 7.2 20.1 10.6 12.2 6.2 5.9 16.0 21.3 8.0 4.2 11.2 15.5 8.4 11.5 5.6 7.2 13.6 6.4 10.8 6.8 13.7 12.0 7.7 9.5 11.0 10.4 17.6 7.4 11.2 9.5 4.2 2.0 3.8 3.1 2.3 3.2 2.5 2.6 2.7 2.1 3.2 4.0 2.6 1.6 3.2 2.2 2.9 3.6 1.2 3.5 4.7 8.5 4.9 3.3 4.0 3.8 4.0 4.0 2.5 3.4 8.3 12.8 0.0 11.0 34.3 16.5 19.5 7.0 7.1 22.2 14.7 14.4 10.2 4.9 4.3 9.6 7.3 27.1 8.4 13.4 5.5 0.0 5.8 119.4 13.3 11.8 14.2 10.3 16.6 47.4 2.3 6.6 13.2 9.2 16.4 5.1 16.2 12.5 11.0 7.8 15.2 40.0 8.9 4.1 8.5 22.9 145.5 9.9 17.2 21.4 27.2 10.2 9.1 10.3 35.2 60.5 4.9 7.4 9.8 14.6 12.1 7.1 4.2 11.1 19.9 6.6 12.7 21.6 60.8 31.4 13.6 20.6 7.3 19.7 10.9 7.6 7.1 VASN SLITL2 ENSG00000168140 Vasorin Q6EMK4 16 4371848-4383538 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 58.7;Fibroblasts: 104.2;Leydig cells: 50.1;Peritubular cells: 60.9;Sertoli cells: 98.6;Smooth muscle cells: 80.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 21.8;MCF7: 18.4;U-2197: 78.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011246, HPA016992" Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria "Secreted - unknown location" NA Yes 2000000000 "Cluster 72: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria "Nucleoplasm, Nucleoli" "HPA011246: AB_1858720, HPA016992: AB_2732418" "unprognostic (2.20e-1)" "unprognostic (2.75e-1)" "unprognostic (9.22e-2)" "prognostic unfavorable (6.24e-5)" "unprognostic (2.35e-3)" "unprognostic (8.91e-3)" "unprognostic (3.15e-3)" "unprognostic (5.92e-2)" "unprognostic (2.22e-1)" "unprognostic (1.24e-2)" "unprognostic (1.08e-1)" "unprognostic (1.28e-1)" "unprognostic (1.81e-1)" "unprognostic (8.82e-3)" "unprognostic (4.23e-2)" "unprognostic (4.95e-3)" "unprognostic (5.27e-2)" 55.7 15.5 1.5 5.8 2.3 2.7 31.5 0.8 2.3 48.1 3.0 12.1 3.4 30.3 0.0 34.1 24.6 7.3 30.5 1.1 0.5 56.1 31.8 44.9 2.8 6.3 5.5 40.0 10.3 0.0 12.8 10.4 1.7 17.9 0.0 0.3 15.9 0.0 6.9 38.8 11.2 0.0 1.6 13.0 13.4 16.8 4.6 0.0 26.8 0.0 0.0 26.5 38.9 2.7 4.2 0.0 0.6 0.5 0.2 0.2 12.6 21.8 0.1 0.0 0.0 1.9 5.5 0.0 4.5 0.3 2.6 0.3 0.0 0.0 0.0 13.7 2.2 0.9 15.9 14.9 0.6 0.0 0.4 7.9 0.0 0.3 0.0 3.1 0.0 0.1 3.1 0.8 0.0 18.4 1.0 5.3 2.2 0.4 2.4 1.0 0.0 0.0 0.0 0.1 1.4 9.3 6.5 13.5 0.6 2.2 6.8 2.5 0.0 17.5 12.5 78.4 4.6 0.0 0.0 0.3 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.3 0.8 2.3 1.1 0.5 6.3 5.5 1.7 1.6 4.6 2.7 10.0 6.4 13.1 5.5 1.4 9.6 7.8 4.2 9.1 0.5 21.9 10.9 16.2 32.9 6.4 23.9 0.0 5.4 2.8 1.5 7.9 13.1 1.1 12.1 58.7 4.6 0.0 0.0 1.1 2.9 7.2 104.2 16.8 20.5 3.8 4.6 2.9 15.3 3.4 0.0 0.9 2.0 2.0 0.6 21.7 2.8 50.1 2.0 14.2 2.8 0.0 18.3 0.0 0.5 0.3 28.3 1.2 60.9 0.8 6.4 0.2 12.3 2.7 0.7 98.6 12.6 80.9 0.8 4.1 3.7 7.5 10.0 3.5 2.3 0.8 4.9 WDHD1 "AND-1, CHTF4, CTF4" ENSG00000198554 "WD repeat and HMG-box DNA binding protein 1" O75717 14 54938949-55027105 "Predicted intracellular proteins, Predicted membrane proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 15.5;Spermatocytes: 15.0;Spermatogonia: 19.3" "Cancer enhanced" "Detected in all" "testis cancer: 23.5" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000632, HPA001122" Enhanced Enhanced Nucleoplasm NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA000632: , HPA001122: AB_1080589" "unprognostic (1.88e-1)" "unprognostic (1.21e-1)" "unprognostic (1.98e-2)" "unprognostic (2.25e-3)" "unprognostic (1.20e-1)" "unprognostic (6.85e-3)" "unprognostic (2.33e-4)" "unprognostic (5.52e-3)" "unprognostic (7.28e-3)" "unprognostic (8.05e-3)" "prognostic unfavorable (9.24e-4)" "unprognostic (5.11e-2)" "unprognostic (2.67e-4)" "unprognostic (8.31e-3)" "unprognostic (1.50e-1)" "unprognostic (3.49e-2)" "unprognostic (2.36e-2)" 1.3 0.8 0.5 3.8 1.0 7.2 2.2 0.9 0.9 1.2 0.1 2.8 1.8 2.1 0.6 2.4 1.6 1.3 0.9 0.7 0.2 1.1 1.2 1.3 5.5 0.2 0.2 1.4 0.9 1.5 0.3 2.8 0.2 1.0 4.0 1.8 0.7 0.8 0.6 2.0 1.7 2.6 0.3 1.7 1.6 5.3 0.4 8.0 0.9 0.8 6.7 1.7 1.1 0.9 39.6 24.7 48.4 21.4 4.6 11.2 28.1 37.5 16.1 29.6 36.0 16.6 25.9 44.9 18.6 10.8 21.4 32.8 72.9 21.5 61.7 30.0 12.7 29.8 23.7 16.2 1.9 56.7 21.8 5.9 3.8 36.6 14.3 7.1 19.6 28.8 37.8 22.0 28.7 21.7 53.5 11.1 38.6 21.1 25.7 49.5 69.7 17.3 8.4 26.0 28.1 19.8 39.8 10.0 12.8 35.1 26.8 11.3 12.8 37.3 43.9 27.5 32.1 6.5 14.4 58.8 17.1 27.4 30.0 1.7 0.3 0.6 0.9 0.2 1.2 1.2 1.0 1.3 0.5 1.8 1.3 1.8 0.4 2.0 0.4 0.7 1.6 0.6 0.5 1.0 0.9 0.9 0.7 0.2 0.2 0.2 0.2 0.3 0.4 0.9 2.3 0.0 2.0 3.9 5.1 3.8 2.2 3.5 3.4 2.9 1.8 1.9 1.7 0.0 4.0 3.7 0.0 8.7 3.6 1.8 0.0 1.8 0.8 1.9 3.1 2.0 0.0 15.5 10.3 1.0 8.4 3.4 2.6 2.5 0.0 12.4 0.7 0.9 4.1 3.3 6.5 2.4 6.1 2.1 1.2 1.1 0.0 2.4 1.8 5.6 1.4 1.4 2.1 4.5 10.1 1.1 0.3 3.0 7.8 0.6 0.5 6.2 3.5 3.1 0.0 2.4 3.0 15.0 19.3 6.1 2.4 2.6 3.6 2.8 5.2 1.7 WDR76 FLJ12973 ENSG00000092470 "WD repeat domain 76" Q9H967 15 43826980-43868412 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.1;lymphoid tissue: 21.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 35.3;Spermatocytes: 23.5;Spermatogonia: 35.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039804, HPA040626" Uncertain Approved "Nucleoli fibrillar center,Nuclear bodies" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies" "Nucleoli fibrillar center" "HPA039804: AB_10795297, HPA040626: AB_10795527" "unprognostic (2.26e-1)" "unprognostic (7.56e-3)" "unprognostic (7.05e-2)" "unprognostic (1.88e-1)" "unprognostic (5.85e-2)" "unprognostic (3.12e-2)" "prognostic unfavorable (6.98e-4)" "prognostic unfavorable (8.02e-5)" "unprognostic (4.24e-3)" "unprognostic (6.25e-2)" "prognostic unfavorable (5.02e-4)" "unprognostic (1.91e-2)" "prognostic unfavorable (1.35e-8)" "unprognostic (7.71e-2)" "unprognostic (9.42e-2)" "unprognostic (4.02e-2)" "unprognostic (3.28e-2)" 2.6 1.2 1.0 8.4 1.1 19.1 3.5 4.8 1.7 3.0 0.8 4.8 3.2 3.3 0.9 4.5 1.7 1.9 1.1 0.7 1.1 1.5 2.2 2.4 19.8 1.3 1.1 2.2 3.1 2.7 1.1 3.9 1.3 1.9 6.0 6.3 2.4 2.0 0.8 4.1 3.3 3.9 1.0 3.6 2.9 5.3 1.3 19.5 2.5 1.3 21.3 2.8 2.8 1.2 35.1 17.5 40.7 31.3 4.5 10.7 11.1 57.3 33.9 61.5 76.8 22.1 17.8 51.4 24.8 26.9 31.0 49.4 42.4 20.5 53.1 80.4 25.2 63.3 52.1 7.3 2.5 65.0 27.0 3.4 3.3 33.8 7.7 8.9 19.9 54.7 48.6 86.9 42.6 12.2 63.4 15.4 14.6 11.0 18.1 66.9 70.1 32.4 11.4 35.5 31.3 30.9 36.1 22.5 7.0 12.6 35.0 31.0 9.1 56.3 26.5 63.5 58.9 42.7 114.6 129.1 40.4 56.7 31.5 0.0 0.6 0.3 3.8 0.5 4.1 1.8 4.6 3.4 1.0 2.2 3.8 2.9 0.0 4.8 0.2 1.2 6.6 2.0 1.0 1.1 4.8 1.7 0.7 1.1 1.3 1.1 1.3 1.0 1.3 1.2 4.1 3.2 1.3 2.6 8.2 7.4 3.2 2.4 4.6 3.7 3.7 2.8 1.2 1.5 2.3 1.8 10.4 12.8 6.2 3.5 1.9 2.9 1.7 1.8 3.9 4.8 0.0 35.3 2.5 4.2 13.0 3.9 4.6 3.3 5.7 12.2 2.9 0.9 8.9 1.7 3.3 3.7 0.0 3.5 5.3 0.9 1.8 3.9 3.6 2.8 3.3 8.0 10.3 0.5 1.9 1.1 3.1 2.2 16.1 1.5 1.4 0.9 0.4 16.2 6.6 5.8 5.7 23.5 35.9 7.4 5.8 3.6 11.6 1.5 9.0 1.8 ZC3H15 LEREPO4 ENSG00000065548 "Zinc finger CCCH-type containing 15" Q8WU90 2 186486253-186509361 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031099, HPA031100, HPA031101" Enhanced Enhanced Cytosol NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Cytosol "HPA031099: AB_10599418, HPA031100: AB_2257403, HPA031101: AB_10611669" "unprognostic (1.51e-1)" "prognostic unfavorable (6.45e-5)" "unprognostic (2.24e-1)" "unprognostic (3.11e-3)" "unprognostic (5.92e-2)" "unprognostic (8.15e-2)" "prognostic unfavorable (1.48e-7)" "unprognostic (9.08e-3)" "unprognostic (4.95e-2)" "prognostic favorable (3.98e-4)" "prognostic unfavorable (9.75e-4)" "unprognostic (5.72e-3)" "unprognostic (5.69e-2)" "unprognostic (1.87e-1)" "unprognostic (1.82e-1)" "unprognostic (8.89e-2)" "unprognostic (3.45e-2)" 42.6 47.5 39.2 44.3 42.0 128.8 45.9 43.4 52.5 35.1 38.6 40.8 48.3 39.8 47.0 40.2 26.3 36.5 37.0 42.6 44.5 53.8 67.3 28.4 53.9 42.2 40.9 32.6 47.9 41.2 27.2 48.8 41.7 37.0 46.0 53.0 45.3 32.4 50.3 44.3 46.1 36.9 39.4 38.6 36.8 40.6 41.7 50.2 49.3 44.9 51.4 54.0 29.2 42.4 103.5 68.9 83.3 107.8 93.0 93.4 124.9 112.7 76.7 102.3 91.5 202.9 81.8 140.3 100.2 80.9 130.9 73.6 155.8 137.5 144.0 128.7 118.1 201.9 101.1 221.9 124.9 208.7 118.6 77.2 149.6 111.4 157.2 89.9 111.9 86.0 197.0 106.8 108.4 93.5 133.7 146.5 157.6 135.7 171.8 105.2 113.0 131.6 127.6 124.0 100.3 73.6 71.5 96.4 167.3 124.3 68.1 149.7 95.7 114.7 99.1 70.9 136.4 92.0 167.0 199.8 101.7 145.7 102.3 59.9 47.9 49.1 44.7 61.6 55.8 55.0 54.8 57.4 54.7 42.2 50.5 53.9 28.8 60.4 75.1 48.0 66.6 41.5 39.2 42.0 43.4 52.5 42.6 44.5 42.2 40.9 41.7 39.4 41.7 42.4 107.1 73.7 83.6 26.4 137.0 212.2 169.1 116.6 99.6 75.0 101.9 118.9 95.8 57.2 104.8 115.8 60.5 131.3 116.1 131.4 256.3 112.0 153.1 110.1 125.5 106.4 101.7 98.7 38.0 104.3 167.0 107.4 67.8 127.1 112.2 220.1 62.4 137.0 124.3 57.2 39.8 136.1 87.5 107.4 104.8 307.1 78.6 113.2 64.0 33.7 142.5 82.6 126.7 19.6 32.8 111.6 106.2 87.3 128.0 179.5 164.1 330.2 68.3 130.2 32.9 156.2 127.6 215.6 174.4 116.1 209.1 177.6 117.3 319.6 151.2 163.5 ZGRF1 "C4orf21, FLJ11331" ENSG00000138658 "Zinc finger GRF-type containing 1" Q86YA3 4 112539333-112636995 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 18.0;Microglial cells: 17.8;Oligodendrocytes: 27.5;Spermatocytes: 22.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA030704, HPA030706" Uncertain Approved Cytosol NA Yes "Cluster 7: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA030704: AB_2673577, HPA030706: AB_10601784" "unprognostic (8.48e-2)" "unprognostic (6.17e-2)" "unprognostic (9.51e-2)" "unprognostic (1.53e-1)" "unprognostic (1.10e-1)" "unprognostic (1.84e-3)" "unprognostic (5.83e-3)" "unprognostic (1.45e-1)" "unprognostic (5.89e-4)" "unprognostic (4.74e-2)" "unprognostic (4.30e-2)" "unprognostic (3.72e-3)" "unprognostic (7.60e-10)" "unprognostic (3.45e-2)" "unprognostic (2.93e-1)" "unprognostic (1.15e-1)" "unprognostic (2.02e-4)" 1.0 0.7 0.9 2.0 1.4 7.8 1.3 2.2 1.5 0.9 0.1 1.1 1.2 1.2 0.3 1.0 0.8 0.5 0.7 0.8 0.7 0.5 0.6 0.9 2.5 1.3 0.9 1.1 0.7 0.3 1.3 1.7 1.3 0.9 1.4 4.3 0.9 0.4 1.2 1.4 1.5 0.9 1.0 1.8 0.9 3.6 1.0 5.2 0.8 0.6 2.9 0.7 0.8 2.1 5.0 3.6 12.1 8.6 0.9 1.6 4.7 8.8 3.7 8.7 7.8 6.9 7.3 13.2 2.5 2.7 3.6 4.0 12.7 4.7 10.0 7.3 3.1 8.3 5.8 2.1 0.4 18.5 5.3 0.8 0.6 11.0 3.0 1.2 3.5 13.6 12.0 14.3 6.0 8.2 25.0 6.7 6.3 5.2 4.2 13.8 18.1 4.5 1.5 4.4 5.6 9.5 3.9 5.3 1.7 8.8 2.5 5.4 4.2 10.9 10.6 5.9 7.1 5.5 10.1 17.0 4.9 6.3 6.3 0.0 0.1 0.3 0.2 0.7 0.1 0.3 0.1 0.0 0.0 0.5 0.4 0.4 0.2 0.2 0.1 0.7 0.2 0.1 0.9 1.4 2.2 1.5 0.8 0.7 1.3 0.9 1.3 1.0 1.0 2.1 3.3 0.0 1.3 10.4 5.4 0.0 1.3 0.0 0.6 10.4 2.1 1.7 2.4 0.0 3.7 1.8 8.4 3.5 10.4 2.1 0.0 1.0 2.9 1.8 3.5 1.9 1.2 11.1 18.0 0.5 2.7 2.3 4.6 2.8 2.5 12.2 1.1 0.6 1.8 5.0 14.5 1.8 0.0 1.6 0.0 2.8 0.6 4.1 0.0 17.8 1.3 1.6 6.2 17.6 27.5 0.6 1.4 2.2 10.5 0.8 0.7 0.3 0.7 17.6 0.0 3.1 2.7 22.1 15.6 3.6 0.0 0.8 5.0 2.2 2.5 0.9 ZNF367 FLJ33970 ENSG00000165244 "Zinc finger protein 367" Q7RTV3 9 96385941-96418370 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 22.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA015319, HPA015785" Uncertain Supported Nucleoplasm NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "HPA015319: AB_2669185, HPA015785: AB_2217750" "unprognostic (5.91e-2)" "unprognostic (2.78e-3)" "unprognostic (2.17e-2)" "unprognostic (1.11e-2)" "unprognostic (2.36e-1)" "unprognostic (4.57e-3)" "unprognostic (7.76e-3)" "unprognostic (1.60e-3)" "unprognostic (4.35e-2)" "unprognostic (3.01e-1)" "unprognostic (3.78e-3)" "unprognostic (2.71e-2)" "unprognostic (4.88e-3)" "unprognostic (3.23e-3)" "unprognostic (1.72e-1)" "prognostic favorable (2.34e-4)" "unprognostic (2.28e-1)" 1.4 0.6 0.7 3.7 1.3 26.1 1.7 1.4 1.3 1.1 0.2 3.0 2.9 1.1 0.1 2.4 0.7 1.0 2.1 0.7 1.0 3.0 10.8 1.1 4.6 1.5 1.4 1.0 1.4 1.6 0.3 1.9 1.4 1.2 3.3 1.3 0.7 0.4 1.5 3.5 3.0 2.4 0.9 1.3 2.1 6.1 1.3 8.7 1.1 2.7 4.7 1.5 1.2 2.7 25.4 10.3 9.9 8.9 3.8 5.3 13.4 34.6 20.4 16.9 20.0 6.4 17.5 19.2 14.4 16.5 12.6 30.5 11.6 12.6 19.9 21.2 10.0 14.0 19.1 5.3 0.0 19.8 16.5 0.9 0.8 13.7 6.9 3.7 6.3 13.3 13.0 45.4 21.7 16.9 30.4 16.1 6.7 27.9 16.7 15.3 49.9 11.7 4.9 16.8 17.4 12.0 15.3 18.1 10.6 8.0 9.4 17.3 5.7 27.6 15.8 25.6 26.6 17.6 32.0 7.8 16.7 17.0 23.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.7 1.3 1.4 1.3 0.7 1.0 1.5 1.4 1.4 0.9 1.3 2.7 1.1 0.0 0.0 2.9 3.8 9.9 1.3 0.4 10.8 0.7 2.2 2.3 2.6 0.0 0.9 0.0 0.0 3.2 2.5 2.4 0.0 0.5 0.7 0.6 1.1 2.0 0.0 22.3 5.1 1.2 4.2 1.7 2.6 1.8 0.0 4.7 1.1 3.8 1.9 0.0 5.3 3.6 0.0 2.1 2.6 0.8 0.6 8.3 3.6 2.8 0.1 0.6 1.0 3.0 7.9 0.7 0.5 0.7 9.6 0.6 0.9 2.5 0.0 1.5 6.6 2.0 3.6 10.3 1.7 10.9 6.5 0.8 5.0 0.3 5.6 1.1 ZNF672 FLJ22301 ENSG00000171161 "Zinc finger protein 672" Q499Z4 1 248838210-248849517 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 71.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055779, HPA062506" Approved Enhanced Nucleoplasm Yes Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 29: U-266 - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA055779: AB_2682917, HPA062506: AB_2684786" "unprognostic (1.64e-2)" "unprognostic (3.45e-2)" "unprognostic (8.96e-2)" "unprognostic (2.92e-2)" "unprognostic (2.50e-1)" "unprognostic (9.54e-3)" "unprognostic (7.42e-3)" "unprognostic (1.08e-2)" "unprognostic (2.50e-1)" "unprognostic (2.40e-2)" "prognostic favorable (7.51e-4)" "unprognostic (9.03e-2)" "unprognostic (1.16e-2)" "unprognostic (1.99e-2)" "unprognostic (2.69e-1)" "unprognostic (8.35e-3)" "prognostic favorable (1.79e-5)" 13.4 14.8 13.4 11.7 14.8 13.5 13.1 17.9 14.1 13.3 14.6 16.1 11.3 14.3 7.7 19.1 14.9 7.8 30.2 12.8 13.4 22.3 26.1 17.0 14.8 17.2 14.8 11.1 18.0 16.2 17.1 9.3 14.8 24.0 8.4 10.7 17.6 8.2 49.5 17.9 16.8 8.1 14.0 19.8 16.9 16.0 14.9 15.8 20.2 35.7 14.0 16.8 13.7 15.8 19.4 21.5 17.2 19.5 9.4 6.6 33.0 17.8 9.7 12.7 13.6 11.8 19.7 22.0 18.1 11.7 9.6 18.8 9.4 13.3 8.0 32.5 5.3 33.7 20.0 16.0 12.0 14.6 24.4 7.4 10.7 16.6 11.5 10.2 11.7 15.2 41.5 17.6 8.8 13.8 26.8 14.5 20.0 22.3 36.5 49.1 16.3 17.4 12.9 15.6 25.5 22.2 16.0 24.0 15.9 10.2 13.8 30.1 10.0 17.5 10.5 11.6 37.3 52.8 22.2 13.2 16.0 25.1 14.5 9.2 16.3 11.9 8.8 15.9 7.2 11.9 6.3 8.8 24.3 15.0 6.7 6.3 9.2 12.7 15.4 13.6 7.8 14.0 13.4 14.8 17.9 14.1 12.8 13.4 17.2 14.8 14.8 14.0 14.9 15.8 10.7 3.2 15.2 5.9 22.3 13.0 28.2 10.1 6.8 22.0 12.8 9.8 20.2 14.3 8.1 16.5 12.5 32.0 22.0 19.5 21.5 18.3 7.8 9.5 5.7 12.0 18.0 17.0 2.2 10.7 19.9 10.0 10.2 8.9 28.0 12.5 7.5 17.2 16.8 10.1 4.0 17.6 8.2 16.4 16.9 14.6 5.6 20.6 12.4 1.9 17.8 19.5 20.6 2.5 5.2 14.6 19.7 5.7 9.6 21.1 26.5 15.8 9.0 30.5 6.6 17.5 11.7 32.4 23.4 5.5 14.6 71.3 13.5 10.6 16.9 22.5 ZNF718 FLJ90036 ENSG00000250312 "Zinc finger protein 718" Q3SXZ3 4 124501-202303 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 37.5;Excitatory neurons: 40.1;Inhibitory neurons: 58.2;Microglial cells: 47.8;Oligodendrocyte precursor cells: 62.8;Oligodendrocytes: 85.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "REH: 19.3" NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (1.96e-1)" "unprognostic (1.38e-1)" "unprognostic (5.61e-2)" "unprognostic (1.15e-2)" "unprognostic (3.62e-2)" "unprognostic (6.59e-3)" "unprognostic (1.01e-2)" "unprognostic (2.41e-2)" "unprognostic (2.60e-1)" "unprognostic (8.97e-2)" "unprognostic (2.01e-1)" "unprognostic (1.99e-1)" "prognostic favorable (7.67e-6)" "unprognostic (1.39e-1)" "unprognostic (6.52e-2)" "unprognostic (1.52e-1)" "unprognostic (1.92e-1)" 1.9 3.0 1.8 2.2 1.8 3.0 2.6 3.4 2.5 3.3 0.5 2.5 1.7 2.2 2.1 1.8 2.9 2.0 1.9 1.3 2.3 2.5 1.4 2.0 3.8 2.0 2.5 3.5 2.5 2.7 2.0 2.8 2.4 3.0 2.2 2.7 2.2 2.2 0.9 3.0 1.9 1.9 1.5 2.9 1.9 2.0 2.4 4.6 4.7 1.8 3.4 2.0 2.3 2.7 0.0 0.9 5.4 0.0 3.3 6.2 1.3 6.9 0.9 4.3 3.3 5.9 7.7 8.5 4.0 2.5 7.6 2.0 4.4 3.2 5.8 0.0 1.6 0.0 1.5 0.0 4.1 0.1 0.1 3.2 2.8 4.3 0.6 3.9 2.9 2.4 4.1 0.1 7.6 4.4 0.8 5.3 6.6 0.0 2.4 19.3 2.1 4.7 3.5 2.1 7.3 1.7 3.5 1.2 4.2 4.3 12.5 1.6 2.1 3.2 4.0 4.1 5.1 0.0 0.0 13.3 0.0 0.0 4.0 2.6 1.3 5.7 2.2 1.8 2.1 2.0 1.9 1.4 2.4 2.2 2.2 2.1 1.6 5.4 1.1 2.4 1.6 1.2 1.8 1.8 3.4 2.5 1.3 2.3 2.0 2.5 2.4 1.5 2.4 2.7 4.0 3.2 3.6 37.5 6.5 2.0 2.2 1.4 4.6 8.4 3.5 3.0 2.4 0.0 5.1 0.0 2.1 1.9 7.6 1.2 0.0 3.1 0.3 1.0 3.7 3.4 1.2 9.7 40.1 1.4 1.4 3.6 4.1 1.6 5.7 6.6 6.1 0.9 1.4 8.4 58.2 0.7 0.0 1.6 1.9 0.7 3.7 2.9 3.6 47.8 1.7 2.6 15.5 62.8 85.0 1.6 0.1 4.5 4.6 0.9 0.5 1.4 2.6 5.1 0.0 4.4 3.8 2.4 4.1 3.0 0.9 1.4 5.5 4.0 0.8 1.4 ZRANB2 "ZIS, ZIS1, ZIS2, ZNF265" ENSG00000132485 "Zinc finger RANBP2-type containing 2" O95218 1 71063291-71081289 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053960, HPA061949, HPA063298" Supported Enhanced Nucleoplasm NA Yes 13000 "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA053960: AB_2682323, HPA061949: AB_2684645, HPA063298: AB_2684979" "unprognostic (2.10e-1)" "unprognostic (7.54e-2)" "unprognostic (4.15e-3)" "unprognostic (8.11e-2)" "unprognostic (1.04e-2)" "unprognostic (2.66e-2)" "prognostic unfavorable (7.29e-5)" "unprognostic (4.25e-3)" "unprognostic (1.24e-2)" "unprognostic (7.79e-2)" "unprognostic (4.54e-2)" "prognostic unfavorable (5.70e-4)" "prognostic unfavorable (1.57e-8)" "unprognostic (3.96e-2)" "unprognostic (8.51e-2)" "unprognostic (1.40e-1)" "unprognostic (1.84e-3)" 41.0 39.4 29.7 45.3 31.1 60.0 52.6 36.9 47.0 45.0 36.8 40.8 35.5 70.7 67.6 29.3 45.4 29.6 42.7 30.7 29.1 35.3 30.2 40.4 62.5 32.0 27.7 56.7 33.8 33.2 64.5 36.3 31.6 44.2 42.9 62.1 39.5 38.0 58.9 43.4 37.9 50.1 29.3 42.6 35.6 50.4 30.3 47.6 48.5 38.9 49.3 37.9 35.2 38.8 86.8 31.1 122.3 73.0 46.5 79.8 71.0 103.2 55.6 89.2 113.2 58.7 55.5 177.6 89.0 64.2 82.7 53.5 111.1 63.9 133.4 127.5 79.9 154.5 127.3 50.0 70.8 171.5 62.7 61.7 80.3 86.1 73.5 98.1 76.3 90.3 165.1 93.6 69.6 29.3 145.0 58.4 128.7 52.9 59.6 159.8 92.3 108.4 60.5 72.6 93.8 58.3 88.7 58.8 91.4 63.7 74.7 76.8 102.5 65.9 62.1 51.9 103.8 75.7 100.6 193.8 96.4 160.3 94.6 99.1 33.4 32.1 44.5 32.3 51.2 68.8 47.5 44.0 26.8 63.1 61.2 48.7 30.7 48.2 33.8 73.4 49.6 31.2 29.7 31.1 36.9 47.0 30.7 29.1 32.0 27.7 31.6 29.3 30.3 38.8 86.9 99.3 154.5 83.6 109.8 50.6 94.4 66.1 59.7 166.5 61.4 66.5 99.9 50.1 68.4 49.7 129.3 55.1 136.9 85.8 49.0 60.2 190.3 79.9 123.5 63.5 73.0 87.1 135.3 68.2 50.4 92.6 62.7 85.7 87.4 132.8 50.7 41.8 45.4 213.7 114.7 64.5 54.9 34.5 39.7 46.2 185.4 55.7 48.0 73.1 74.8 116.6 139.0 90.5 131.9 69.2 76.5 115.5 127.5 54.8 41.2 41.1 76.5 202.2 118.3 88.1 99.2 218.7 113.0 55.3 46.5 63.5 89.6 96.4 55.1 68.5 ZSCAN31 "ZNF310P, ZNF323" ENSG00000235109 "Zinc finger and SCAN domain containing 31" Q96LW9 6 28324693-28356271 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 138.5;Late spermatids: 65.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "basophil: 17.6" "Lineage enriched" "Detected in many" 10 "granulocytes: 17.6" "Cell line enhanced" "Detected in many" "CAPAN-2: 29.5;EFO-21: 40.1;TIME: 31.0;U-2 OS: 47.6" "Low region specificity" "Detected in all" HPA007124 Approved Approved Nucleoplasm,Cytosol NA Yes "Cluster 18: Basophils - Vesicular transport" "Cluster 21: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm Cytosol "HPA007124: AB_1080703" "unprognostic (1.11e-1)" "unprognostic (4.23e-2)" "unprognostic (3.54e-3)" "unprognostic (1.68e-1)" "unprognostic (2.45e-3)" "unprognostic (6.90e-2)" "unprognostic (2.77e-1)" "unprognostic (1.29e-2)" "unprognostic (2.41e-2)" "unprognostic (4.96e-2)" "unprognostic (6.07e-2)" "unprognostic (5.10e-2)" "prognostic favorable (2.19e-5)" "unprognostic (8.43e-3)" "unprognostic (6.22e-2)" "unprognostic (1.19e-1)" "unprognostic (5.64e-2)" 5.3 3.4 10.5 2.5 12.9 4.7 13.0 24.1 18.3 8.1 4.4 9.9 4.1 19.2 9.5 11.3 7.9 18.7 7.9 15.5 8.7 6.2 5.6 10.7 2.5 14.0 10.8 19.7 7.2 4.4 6.2 3.0 14.6 8.3 6.1 8.2 6.4 9.3 9.6 13.4 4.4 12.6 11.7 2.7 16.9 20.9 12.7 4.6 13.5 8.0 4.1 5.7 6.3 21.2 2.0 2.7 4.1 19.1 0.7 0.9 6.0 0.9 1.2 0.9 0.8 2.5 29.5 0.5 40.1 1.4 5.9 6.2 2.1 1.8 0.6 3.6 1.7 6.5 16.0 4.5 1.7 14.0 8.3 0.7 16.2 1.1 1.7 1.9 28.0 5.4 7.7 4.9 4.3 2.9 2.4 3.4 1.3 1.4 12.1 6.2 3.7 3.7 2.8 2.5 13.6 3.7 26.3 16.6 3.9 3.0 8.4 4.7 31.0 6.1 47.6 1.2 2.2 2.1 3.3 0.5 0.7 6.7 1.4 17.6 0.3 0.6 1.3 0.2 1.2 1.2 1.1 1.0 0.3 1.0 0.8 1.2 0.2 1.3 0.3 1.8 0.2 0.3 10.5 12.9 24.1 18.3 15.5 8.7 14.0 10.8 14.6 11.7 12.7 21.2 7.0 28.9 3.3 15.7 0.5 0.8 2.4 7.5 14.8 8.9 3.3 2.8 7.6 2.8 11.6 3.7 0.0 1.9 1.8 4.9 7.9 2.9 138.5 6.6 1.5 7.4 6.0 0.8 27.9 8.1 0.9 4.1 10.2 5.8 2.5 2.2 1.8 4.8 0.7 1.7 11.7 2.5 16.2 0.8 1.2 65.0 3.7 0.7 1.8 4.7 0.7 7.2 1.0 4.0 18.5 4.8 2.6 5.3 2.0 1.4 1.2 8.1 3.9 5.9 6.6 2.7 3.4 11.2 4.5 6.8 2.3 0.8 1.1 2.3 3.3 1.5