Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ACACA "ACAC, ACC, ACC1" ENSG00000278540 "Acetyl-CoA carboxylase alpha" Q13085 17 37084992-37406836 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Allosteric enzyme, Ligase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 138.1;Excitatory neurons: 230.7;Inhibitory neurons: 197.8;Oligodendrocyte precursor cells: 181.0;Oligodendrocytes: 186.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013715, HPA036650, HPA063018" Approved Supported "Nucleoli fibrillar center,Actin filaments,Cytosol" NA NA 110000 "Cluster 30: Non-specific - Translation" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "Nucleoli fibrillar center, Actin filaments" "CAB013715: , HPA036650: AB_2675228, HPA063018: AB_2684922" "unprognostic (1.96e-2)" "unprognostic (1.07e-2)" "unprognostic (3.04e-2)" "unprognostic (1.10e-1)" "unprognostic (4.86e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.24e-5)" "unprognostic (8.81e-2)" "unprognostic (6.56e-2)" "unprognostic (2.38e-3)" "unprognostic (3.38e-1)" "unprognostic (2.24e-1)" "unprognostic (6.72e-2)" "unprognostic (1.18e-1)" "unprognostic (4.89e-1)" "unprognostic (4.49e-2)" "unprognostic (2.03e-2)" 16.2 25.4 10.8 3.7 10.8 4.9 22.2 9.0 15.8 11.5 11.3 14.4 5.2 12.1 13.8 25.2 10.8 4.8 7.7 9.5 11.2 13.6 23.3 13.3 2.0 11.1 9.9 11.3 10.5 10.9 19.2 3.8 11.1 26.2 6.4 8.0 14.6 9.6 15.1 15.4 9.6 8.0 8.6 7.3 12.6 16.4 10.3 3.7 8.9 3.6 5.5 19.9 14.6 12.3 34.7 7.0 39.8 42.6 54.7 53.2 13.9 15.2 21.3 15.9 27.5 27.4 5.9 5.0 12.0 24.3 39.4 33.9 7.5 51.1 23.7 13.6 23.2 27.3 15.5 28.0 9.2 14.8 5.3 43.4 29.0 40.2 30.0 18.8 27.5 25.1 66.5 3.2 2.1 27.3 16.3 22.8 30.4 21.5 22.1 24.1 25.3 6.4 36.1 38.5 45.0 17.0 27.8 12.3 12.7 34.8 24.9 16.8 23.8 12.7 20.6 17.3 3.9 8.7 11.5 42.0 11.7 12.3 17.2 0.5 0.8 0.1 0.6 1.3 0.6 0.7 0.7 0.7 1.0 1.1 1.1 0.8 0.3 0.6 0.8 0.7 1.0 0.6 10.8 10.8 9.0 15.8 9.5 11.2 11.1 9.9 11.1 8.6 10.3 12.3 6.8 32.1 51.7 138.1 8.0 11.6 20.8 14.8 22.2 17.2 17.3 11.7 8.0 2.8 16.5 11.0 27.1 16.0 7.0 5.3 9.8 6.7 66.3 19.1 15.6 8.3 9.0 10.7 230.7 8.3 7.6 10.4 15.8 15.9 7.0 19.5 6.4 17.3 5.8 23.5 197.8 7.3 14.2 3.8 4.3 51.2 9.9 6.1 10.6 58.1 4.3 18.2 4.1 181.0 186.9 7.2 6.4 15.8 9.3 22.8 4.8 7.0 10.5 11.8 6.6 10.0 7.8 20.8 20.5 27.8 15.9 16.3 6.4 43.2 10.0 22.0 ACTN1 ENSG00000072110 "Actinin alpha 1" P12814 14 68874128-68979440 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "smooth muscle: 524.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 351.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 364.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004303, HPA006035" Approved Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 210000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Actin filaments, Focal adhesion sites" "CAB004303: AB_626633, HPA006035: AB_1078095" "unprognostic (4.40e-2)" "unprognostic (1.03e-3)" "unprognostic (2.49e-2)" "unprognostic (1.96e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (6.19e-3)" "prognostic unfavorable (7.63e-5)" "unprognostic (3.62e-1)" "unprognostic (3.23e-2)" "unprognostic (3.16e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (9.08e-10)" "unprognostic (2.87e-2)" "unprognostic (2.00e-1)" "unprognostic (6.05e-3)" "prognostic unfavorable (8.00e-4)" 117.4 40.7 27.3 149.5 55.8 149.3 103.5 0.1 32.0 118.4 20.1 449.8 49.8 313.1 60.3 154.4 152.1 143.9 121.4 29.7 14.7 46.7 61.8 100.0 47.5 24.5 11.0 61.8 46.8 9.1 27.3 96.1 7.3 174.3 109.0 28.2 116.4 295.1 21.7 59.3 106.9 524.5 4.2 55.9 171.7 21.2 32.9 32.6 35.0 13.3 50.7 305.9 83.3 28.8 871.9 262.3 158.6 121.4 275.2 180.5 592.4 749.3 712.0 770.0 571.1 211.8 196.6 0.7 256.5 744.7 310.4 370.9 126.8 790.3 965.2 4.6 38.5 118.2 133.5 179.0 494.0 85.4 14.3 231.7 152.1 479.8 540.3 551.6 428.6 48.2 56.9 1.4 612.0 246.9 10.1 181.1 124.7 217.9 198.1 59.3 294.1 32.6 292.0 225.6 57.0 68.7 649.9 96.8 177.1 474.8 146.0 170.9 546.0 1085.2 432.8 126.9 662.5 113.8 47.8 3.9 314.4 115.7 584.4 64.6 67.5 137.1 5.7 28.8 7.1 0.1 22.7 12.4 45.5 0.2 103.9 92.2 364.2 4.5 8.9 2.0 9.6 89.2 27.3 55.8 0.1 32.0 29.7 14.7 24.5 11.0 7.3 4.2 32.9 28.8 44.7 38.5 25.1 19.6 4.0 119.3 154.9 137.4 82.0 74.7 88.6 157.6 60.3 51.5 36.0 42.3 246.0 155.3 3.0 17.2 3.9 186.8 34.0 65.8 112.8 135.5 38.5 21.9 102.7 144.9 351.8 88.9 34.1 90.2 7.6 15.9 129.5 96.6 79.5 18.5 29.7 57.3 59.0 100.9 82.1 10.7 35.8 96.4 30.2 34.7 105.1 6.0 4.1 9.0 4.3 203.7 28.0 245.6 0.6 132.6 2.4 15.3 47.8 80.8 177.5 30.0 270.6 19.4 18.4 51.8 59.8 66.9 22.7 20.9 47.0 67.1 ACTN4 FSGS1 ENSG00000130402 "Actinin alpha 4" O43707 19 38647649-38731589 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 626.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 947.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001873, HPA006035" Supported Approved "Nuclear bodies,Actin filaments,Cytosol" NA NA 71000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear bodies, Actin filaments" Cytosol "HPA001873: AB_1078096, HPA006035: AB_1078095" "unprognostic (1.03e-1)" "unprognostic (6.34e-2)" "unprognostic (2.97e-2)" "unprognostic (2.52e-2)" "unprognostic (2.37e-1)" "unprognostic (3.34e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (8.82e-4)" "unprognostic (1.70e-1)" "unprognostic (5.85e-3)" "prognostic unfavorable (5.65e-4)" "unprognostic (2.99e-1)" "prognostic favorable (5.25e-5)" "unprognostic (6.59e-2)" "unprognostic (1.91e-1)" "unprognostic (6.75e-3)" "unprognostic (6.52e-2)" 176.5 160.8 22.9 63.9 42.0 74.2 151.4 42.9 42.2 165.2 58.5 168.5 128.7 269.4 11.8 232.8 163.2 46.8 89.0 19.5 27.8 166.7 85.0 174.7 37.5 45.9 42.4 102.5 90.6 42.2 80.0 85.7 44.8 115.6 42.2 26.0 148.1 59.0 52.2 183.4 150.3 73.1 30.2 118.1 120.9 23.6 38.1 18.5 105.4 18.8 24.2 150.2 181.3 63.4 364.6 947.0 92.9 48.6 37.7 50.6 237.2 198.7 162.5 178.8 143.9 335.9 265.1 99.0 409.1 260.6 117.4 185.1 57.4 203.8 38.3 238.3 69.5 139.7 356.1 240.4 103.4 101.7 145.2 95.3 63.4 157.5 79.6 146.9 116.4 26.3 165.0 71.8 127.5 221.2 27.2 44.1 78.4 197.8 177.3 89.5 109.4 43.8 174.6 396.3 83.0 49.8 366.3 210.5 94.7 64.0 94.5 78.8 309.7 249.3 138.7 135.3 476.1 44.1 84.5 67.8 231.7 90.6 476.7 7.6 8.1 17.8 13.2 7.7 9.8 3.2 5.7 13.2 7.0 3.0 0.9 4.4 16.9 24.8 6.7 10.8 9.5 10.6 22.9 42.0 42.9 42.2 19.5 27.8 45.9 42.4 44.8 30.2 38.1 63.4 315.2 179.5 120.0 21.5 45.8 234.8 266.4 155.1 153.7 25.6 134.0 148.1 9.2 143.0 119.4 152.6 14.6 123.7 150.7 626.1 19.6 413.5 2.5 272.0 145.7 206.2 162.0 59.3 46.0 419.3 256.7 77.3 219.7 346.4 73.5 75.9 130.6 108.5 72.6 23.5 22.6 365.5 73.2 65.9 103.7 4.5 41.3 75.4 46.2 48.7 162.2 122.4 120.5 35.2 83.6 532.3 425.2 71.5 91.2 322.1 315.5 104.0 122.1 32.3 190.7 97.2 251.0 36.2 23.7 189.3 202.7 168.0 119.4 115.3 280.6 284.7 AFAP1 "AFAP, AFAP-110" ENSG00000196526 "Actin filament associated protein 1" Q8N556 4 7758714-7939926 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Early spermatids: 170.5;Extravillous trophoblasts: 116.3;Inhibitory neurons: 117.2;Late spermatids: 373.8;Oligodendrocyte precursor cells: 125.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.9" "Group enriched" "Detected in many" 5 "granulocytes: 2.9;T-cells: 1.2" "Cell line enhanced" "Detected in many" "TIME: 126.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015642, CAB024712" Enhanced Supported "Actin filaments,Focal adhesion sites,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Actin filaments, Cytosol" "Focal adhesion sites" "CAB024712: , HPA015642: AB_1844632" "unprognostic (1.12e-1)" "unprognostic (2.78e-2)" "unprognostic (3.97e-1)" "unprognostic (7.29e-2)" "unprognostic (2.02e-1)" "unprognostic (1.93e-1)" "unprognostic (3.30e-1)" "prognostic unfavorable (2.84e-4)" "unprognostic (2.00e-1)" "unprognostic (3.39e-2)" "unprognostic (3.40e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (8.18e-4)" "unprognostic (1.40e-2)" "unprognostic (1.56e-1)" "unprognostic (1.85e-1)" "unprognostic (2.44e-2)" 12.6 3.1 7.0 8.7 5.8 0.7 9.7 4.5 6.9 8.7 2.9 17.6 5.6 15.4 2.0 11.0 8.5 9.4 10.8 5.8 4.5 4.9 1.2 8.5 4.4 3.7 2.7 7.1 3.8 14.7 7.9 12.6 2.8 7.7 9.8 3.4 8.6 10.2 3.5 5.3 7.7 15.4 3.4 4.0 6.7 22.0 3.5 3.1 7.4 2.4 4.8 14.2 8.3 3.5 31.9 23.2 16.2 12.9 15.4 27.8 21.3 46.4 68.1 43.6 40.0 7.4 7.2 0.1 15.2 75.5 72.3 15.1 8.6 18.7 28.6 0.9 5.7 0.0 33.2 4.5 43.0 0.0 0.4 17.2 13.8 54.4 35.5 72.2 53.0 4.8 0.7 6.8 23.0 10.3 0.6 0.0 7.0 13.2 44.3 0.0 12.1 1.5 4.7 4.1 31.8 53.0 15.9 10.9 12.4 21.4 4.1 0.3 126.7 53.0 11.8 69.6 23.0 0.0 0.2 0.0 18.9 0.1 61.9 0.0 0.4 2.9 0.4 0.1 0.5 0.0 0.6 0.6 0.0 0.0 1.2 0.5 1.0 0.0 0.0 0.0 0.5 0.7 7.0 5.8 4.5 6.9 5.8 4.5 3.7 2.7 2.8 3.4 3.5 3.5 22.5 6.4 2.0 4.6 0.2 2.9 9.7 16.2 7.4 1.2 10.2 8.9 5.9 10.0 12.7 11.0 4.2 5.6 2.3 14.8 0.0 19.2 170.5 7.5 17.6 20.1 14.5 0.0 24.7 7.7 116.3 21.1 11.2 8.8 0.0 4.4 14.3 0.0 8.5 0.0 117.2 20.6 0.0 0.3 3.6 373.8 11.1 6.0 1.8 30.9 0.6 10.2 0.0 125.2 5.4 29.9 8.6 12.4 0.6 13.5 6.4 4.2 6.4 0.7 6.6 8.0 13.4 12.5 10.0 6.2 4.3 8.8 7.3 2.6 13.9 9.9 ANKRD23 "DARP, FLJ32449, MARP3" ENSG00000163126 "Ankyrin repeat domain 23" Q86SG2 2 96824526-96857934 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 39 "skeletal muscle: 1438.6;tongue: 448.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 5.0;Respiratory ciliated cells: 7.4;Rod photoreceptor cells: 5.2;Skeletal myocytes: 6.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "Karpas-707: 38.5" "Low region specificity" "Detected in many" HPA036201 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 2: Karpas-707 - Immune response" "Cluster 37: Myocytes - Muscle contraction" "Nucleoplasm, Cytosol" "Actin filaments" "HPA036201: AB_10673347" "unprognostic (2.48e-1)" "unprognostic (7.83e-4)" "unprognostic (4.93e-4)" "unprognostic (1.21e-2)" "unprognostic (4.28e-1)" "unprognostic (3.28e-1)" "unprognostic (3.27e-2)" "unprognostic (6.66e-2)" "unprognostic (2.46e-2)" "unprognostic (3.59e-2)" "unprognostic (1.81e-4)" "unprognostic (1.43e-1)" "unprognostic (2.04e-6)" "unprognostic (2.70e-1)" "unprognostic (1.39e-1)" "unprognostic (1.54e-1)" "unprognostic (2.70e-4)" 0.8 0.9 1.6 0.4 2.1 0.7 1.2 2.2 2.1 1.4 0.6 1.3 0.8 1.8 0.0 6.0 2.5 0.2 24.2 1.5 1.4 0.7 2.2 1.0 0.6 2.5 1.6 1.7 1.6 0.3 10.4 0.2 1.8 5.3 0.1 0.1 18.5 0.3 1438.6 2.5 1.3 0.2 1.5 2.3 0.7 0.7 1.9 0.6 1.1 448.6 0.4 1.2 1.1 2.3 0.5 0.7 0.4 0.8 0.0 0.2 1.1 0.3 0.1 0.2 0.1 0.1 0.2 0.4 0.2 0.1 0.3 0.3 0.3 0.3 0.2 1.1 1.0 0.5 0.8 0.2 0.1 0.8 1.8 0.3 0.3 0.6 0.0 0.2 0.1 1.5 0.9 38.5 0.3 0.9 0.5 0.8 0.4 0.1 0.3 1.4 0.0 5.0 0.2 0.9 1.4 0.2 0.3 0.7 0.0 0.2 1.1 0.0 0.3 0.5 0.6 0.7 0.1 1.7 0.7 0.3 0.4 1.1 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 2.1 2.2 2.1 1.5 1.4 2.5 1.6 1.8 1.5 1.9 2.3 1.1 0.0 1.1 2.0 0.5 0.8 0.5 0.4 0.6 2.6 0.8 2.3 5.0 0.0 1.5 0.0 2.1 0.4 2.1 0.9 0.0 0.3 3.3 1.3 1.9 0.8 0.0 0.4 2.8 1.1 0.2 1.3 0.5 0.7 1.3 1.1 1.4 1.2 0.2 1.7 2.7 1.0 0.0 0.6 0.3 1.8 1.5 0.6 0.0 1.0 0.2 1.1 1.0 0.5 2.9 0.1 0.3 3.0 0.4 0.3 0.6 0.2 7.4 5.2 0.0 6.1 1.6 1.3 0.4 0.4 1.3 0.3 1.1 0.7 0.9 0.2 ANKRD62 DKFZp779B1634 ENSG00000181626 "Ankyrin repeat domain 62" A6NC57 18 12093843-12129764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "brain: 1.1;pancreas: 1.0;testis: 1.6" "Cell type enriched" "Detected in some" 5 "Spermatocytes: 92.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059835 Enhanced Uncertain "Nucleoplasm,Nuclear bodies,Actin filaments" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "Actin filaments" "HPA059835: AB_2684136" "unprognostic (2.45e-2)" "unprognostic (1.18e-1)" "unprognostic (2.37e-3)" "unprognostic (9.46e-2)" "unprognostic (3.01e-1)" "unprognostic (1.98e-1)" "unprognostic (6.61e-2)" "unprognostic (7.95e-2)" "unprognostic (3.27e-1)" "unprognostic (2.55e-4)" "unprognostic (1.13e-1)" "unprognostic (3.28e-2)" "unprognostic (4.52e-3)" "unprognostic (8.70e-2)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.4 0.0 0.6 0.0 0.7 0.0 0.0 0.4 0.1 0.0 1.3 0.3 0.1 0.4 0.3 0.0 0.0 1.7 0.4 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 2.2 0.1 0.2 0.5 0.0 0.0 16.5 1.7 0.6 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.6 0.8 2.6 0.6 0.2 0.0 1.0 0.0 0.1 1.0 1.0 0.2 0.5 1.1 0.4 0.0 0.8 0.2 0.0 0.0 0.9 0.0 1.3 0.3 92.8 15.8 0.5 1.1 0.0 0.2 0.1 0.2 0.5 ARHGAP21 "ARHGAP10, KIAA1424" ENSG00000107863 "Rho GTPase activating protein 21" Q5T5U3 10 24583609-24723887 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 111.2" "Cell type enhanced" "Detected in all" "Excitatory neurons: 266.5;Oligodendrocyte precursor cells: 336.7;Oligodendrocytes: 827.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036610, HPA057861" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Cell Junctions, Actin filaments" "Plasma membrane" "HPA036610: AB_10669910, HPA057861: AB_2683546" "unprognostic (7.65e-2)" "unprognostic (1.61e-2)" "unprognostic (1.88e-1)" "unprognostic (5.84e-2)" "unprognostic (2.69e-1)" "unprognostic (3.59e-1)" "unprognostic (1.12e-3)" "unprognostic (5.35e-2)" "unprognostic (9.75e-2)" "unprognostic (3.34e-2)" "unprognostic (2.65e-3)" "unprognostic (3.23e-1)" "unprognostic (3.14e-2)" "unprognostic (1.53e-1)" "unprognostic (3.32e-1)" "unprognostic (1.43e-2)" "unprognostic (2.61e-2)" 28.4 18.0 44.3 10.3 77.7 7.2 16.1 56.7 58.1 19.7 0.0 16.6 12.9 19.9 8.6 10.8 17.5 17.9 21.2 49.1 48.3 11.0 13.1 21.7 5.3 76.3 63.1 31.9 14.9 14.6 12.1 16.6 66.7 10.8 18.5 41.3 24.5 11.5 17.7 6.8 16.3 17.8 48.4 8.9 27.1 14.6 58.0 11.4 12.8 23.0 6.0 13.8 9.0 111.2 59.0 25.1 60.9 52.3 42.2 59.1 21.6 41.6 26.6 24.5 34.0 18.4 36.8 10.9 14.0 64.3 37.7 38.1 31.6 40.4 35.9 38.0 20.5 64.9 54.7 13.8 25.5 0.0 9.9 24.4 45.0 32.1 34.4 36.9 42.3 16.1 27.9 96.3 50.0 11.6 30.2 2.3 9.7 20.8 13.6 7.0 21.4 6.2 17.2 10.2 10.5 10.9 27.9 16.0 32.6 18.1 16.3 9.1 47.8 35.3 22.7 40.0 30.6 11.0 20.3 7.8 36.2 11.4 24.7 0.9 0.2 0.4 0.1 0.4 0.1 0.0 0.2 0.3 0.3 0.0 0.6 0.3 0.0 0.2 0.2 0.4 0.4 0.2 44.3 77.7 56.7 58.1 49.1 48.3 76.3 63.1 66.7 48.4 58.0 111.2 47.9 86.6 33.1 246.8 6.5 29.6 13.2 23.6 14.8 144.0 17.5 26.0 37.4 24.3 45.0 5.5 68.8 23.8 6.9 44.6 1.9 21.4 5.0 36.2 148.7 34.9 16.2 15.2 266.5 27.6 21.0 73.0 82.0 54.2 17.1 135.8 26.0 20.9 14.6 132.9 153.8 28.3 14.2 32.8 31.8 8.3 92.9 38.9 19.6 171.4 11.0 194.0 2.1 336.7 827.4 37.1 34.6 59.5 15.2 27.4 21.9 6.5 30.3 53.5 26.3 60.4 43.2 27.4 35.6 18.1 20.2 12.6 11.8 62.2 29.0 29.5 ARHGAP33 "FLJ39019, SNX26, TCGAP" ENSG00000004777 "Rho GTPase activating protein 33" O14559 19 35774532-35788822 "Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 27.4;Cone photoreceptor cells: 25.0;Horizontal cells: 20.2;Oligodendrocytes: 22.7;Rod photoreceptor cells: 33.7;Spermatocytes: 22.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 58.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030117, HPA030118" Supported Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 43: Testis - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "Actin filaments, Cytosol" "HPA030117: AB_10599306, HPA030118: AB_10601238" "unprognostic (1.44e-3)" "unprognostic (3.40e-2)" "unprognostic (1.07e-1)" "unprognostic (3.33e-2)" "unprognostic (2.66e-1)" "unprognostic (2.82e-3)" "unprognostic (3.61e-3)" "unprognostic (4.80e-2)" "unprognostic (1.45e-1)" "unprognostic (2.99e-2)" "unprognostic (2.97e-3)" "unprognostic (2.40e-2)" "prognostic unfavorable (3.09e-8)" "unprognostic (5.70e-2)" "unprognostic (2.66e-1)" "unprognostic (1.38e-1)" "unprognostic (1.19e-2)" 7.7 8.7 24.3 4.2 28.8 20.5 10.9 14.3 39.1 20.4 8.2 11.2 4.0 13.9 1.3 8.1 17.1 2.8 6.9 30.0 21.0 10.1 5.6 6.8 5.8 19.9 16.5 26.9 11.9 4.2 33.6 1.6 18.0 12.5 1.3 9.9 7.4 3.3 3.4 9.8 9.2 2.0 15.2 11.1 10.4 39.6 19.5 11.7 18.0 1.3 2.2 9.4 13.7 22.1 9.0 5.6 15.5 11.7 0.6 1.5 1.2 7.2 0.9 2.7 1.9 2.3 6.6 5.2 2.6 2.1 2.3 2.4 1.9 2.0 1.0 16.4 3.6 7.6 8.6 2.1 0.7 2.7 58.1 2.2 0.4 2.1 0.8 2.2 1.6 20.4 3.7 22.1 2.4 6.8 18.8 7.4 3.5 3.4 2.5 25.4 2.5 2.5 1.2 1.4 15.4 9.4 3.2 5.7 1.1 1.9 8.3 7.5 3.1 11.0 10.6 5.8 8.5 19.5 4.0 5.2 4.0 8.9 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.3 28.8 14.3 39.1 30.0 21.0 19.9 16.5 18.0 15.2 19.5 22.1 2.7 0.0 1.1 7.8 1.0 1.7 1.0 1.0 4.6 27.4 4.8 4.7 2.3 2.8 2.7 1.8 25.0 0.7 5.1 1.4 0.0 0.4 11.4 6.1 4.8 1.6 3.5 6.5 12.1 0.7 1.0 3.5 3.6 2.5 5.1 7.3 1.1 1.5 1.2 20.2 11.3 2.3 2.0 0.8 1.9 8.9 4.1 0.7 0.0 1.9 0.2 7.3 0.0 19.1 22.7 0.7 0.6 3.0 2.2 0.6 0.3 0.2 4.2 33.7 0.0 4.6 3.1 22.2 6.2 4.2 1.7 0.4 3.6 7.2 2.8 0.6 ARL13A ARL13 ENSG00000174225 "ADP ribosylation factor like GTPase 13A" Q5H913 X 100969708-100990831 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "testis: 5.1" "Group enriched" "Detected in some" 29 "Early spermatids: 69.8;Late spermatids: 55.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "CACO-2: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA037377, HPA037378" Uncertain Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" "Actin filaments, Cytosol" "HPA037377: AB_2675442, HPA037378: AB_10670932" "unprognostic (4.40e-2)" "unprognostic (1.05e-1)" "unprognostic (1.02e-1)" "unprognostic (1.08e-2)" "unprognostic (1.93e-1)" "unprognostic (9.06e-3)" "unprognostic (2.58e-1)" "unprognostic (3.95e-2)" "unprognostic (1.82e-1)" "unprognostic (1.06e-1)" "unprognostic (1.18e-1)" "unprognostic (1.51e-2)" "unprognostic (4.50e-3)" "unprognostic (1.46e-1)" "unprognostic (2.46e-1)" "unprognostic (9.37e-4)" "unprognostic (2.14e-1)" 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.7 0.2 0.0 0.0 0.1 0.1 5.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.4 0.6 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.4 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.6 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 55.5 0.6 0.0 0.0 0.0 0.0 1.6 0.0 0.5 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ATP12A "ATP1AL1, H-K-ATPase, HK" ENSG00000075673 "ATPase H+/K+ transporting non-gastric alpha2 subunit" P54707 13 24680408-24712472 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Potassium transport, Sodium transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 11.2;kidney: 5.4;lymphoid tissue: 14.8;placenta: 5.6;skin 1: 6.2" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 75.6;Club cells: 49.2" "Cancer enhanced" "Detected in many" "testis cancer: 12.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "SuSa: 4.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA039526 Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane, Actin filaments" Cytosol "HPA039526: AB_10673534" "unprognostic (8.33e-3)" "unprognostic (3.58e-2)" "unprognostic (2.93e-1)" "unprognostic (5.21e-3)" "unprognostic (2.58e-1)" "unprognostic (1.21e-2)" "unprognostic (8.03e-3)" "unprognostic (2.64e-1)" "unprognostic (1.50e-1)" "unprognostic (1.18e-1)" "unprognostic (3.39e-1)" "unprognostic (2.24e-1)" "unprognostic (1.78e-1)" "unprognostic (1.67e-1)" "unprognostic (6.80e-2)" "unprognostic (8.22e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.1 0.0 5.4 0.0 0.6 0.0 0.0 0.1 0.0 0.1 0.6 0.0 5.6 0.0 0.2 2.0 0.0 0.1 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 14.8 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.7 1.0 0.0 0.0 0.0 75.6 0.0 0.0 0.2 0.3 0.4 0.0 49.2 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.3 0.5 0.0 0.0 0.0 0.9 0.0 0.0 0.4 0.0 2.2 1.3 0.0 0.0 0.0 0.0 0.0 0.7 0.2 8.2 0.0 0.0 0.1 0.3 0.1 0.0 1.0 0.0 0.0 0.0 1.0 0.6 0.1 1.2 0.0 0.0 0.2 0.0 0.1 13.6 0.0 0.0 0.0 1.8 1.0 1.1 0.0 0.0 0.0 0.1 0.0 0.1 1.3 ATP6V1H "CGI-11, SFD, SFDalpha, SFDbeta, VMA13" ENSG00000047249 "ATPase H+ transporting V1 subunit H" Q9UI12 8 53715543-53843558 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009532, HPA023421" Approved Supported "Plasma membrane,Actin filaments,Cytosol" NA NA 8300 "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Actin filaments, Cytosol" "Plasma membrane" "CAB009532: AB_667834, HPA023421: AB_1845202" "unprognostic (1.67e-3)" "unprognostic (2.53e-2)" "unprognostic (1.41e-2)" "unprognostic (2.16e-2)" "unprognostic (2.38e-1)" "unprognostic (2.25e-2)" "prognostic unfavorable (7.81e-4)" "unprognostic (2.01e-1)" "unprognostic (1.95e-1)" "unprognostic (6.39e-3)" "unprognostic (1.56e-1)" "unprognostic (5.30e-2)" "prognostic favorable (1.46e-7)" "unprognostic (1.06e-1)" "unprognostic (3.37e-2)" "unprognostic (1.38e-2)" "unprognostic (1.64e-1)" 24.1 44.6 42.5 15.9 46.7 25.6 26.0 27.5 58.8 23.9 30.2 31.6 12.9 25.4 32.9 34.1 22.6 20.7 31.2 57.4 38.0 60.5 19.1 24.2 21.4 30.5 30.2 24.1 17.4 47.7 42.4 23.9 32.7 30.2 20.4 37.4 28.7 27.4 37.8 35.2 19.1 24.1 29.4 20.3 31.8 18.5 31.0 26.6 52.4 27.3 22.0 28.5 26.4 37.9 42.8 35.6 29.8 31.8 50.9 32.9 23.4 40.5 44.5 54.8 56.7 33.5 54.1 27.2 38.7 40.9 69.7 67.8 52.6 58.9 56.1 39.9 35.8 28.8 34.3 40.9 69.1 19.6 31.8 46.5 82.3 37.2 66.4 52.5 37.8 28.9 39.4 14.0 81.6 36.0 30.6 32.5 27.4 37.0 17.4 28.2 10.6 18.6 88.4 67.4 23.5 34.9 28.7 54.6 79.5 34.4 64.0 16.3 43.2 24.4 19.7 54.6 25.5 25.9 30.4 32.3 57.8 27.4 27.5 25.7 14.8 36.2 13.2 16.6 14.9 13.6 14.3 15.4 20.2 12.0 14.4 16.0 14.5 22.6 23.4 15.9 20.7 11.8 42.5 46.7 27.5 58.8 57.4 38.0 30.5 30.2 32.7 29.4 31.0 37.9 18.2 38.5 27.4 84.2 39.0 29.6 40.1 55.5 42.1 72.8 27.8 21.0 28.9 38.6 50.3 58.8 112.6 76.0 35.9 39.0 105.7 49.1 8.3 94.1 27.7 25.4 35.3 27.0 154.7 31.1 43.6 23.6 26.0 145.7 15.8 22.0 28.9 21.9 64.7 62.2 105.8 17.4 75.3 43.0 103.6 8.5 43.2 52.9 30.2 42.2 35.1 48.4 37.0 58.3 57.7 44.1 30.1 48.2 20.9 32.5 31.4 64.9 39.6 76.4 19.7 16.8 24.6 28.5 52.9 37.6 31.4 100.0 38.1 36.4 21.8 41.4 AVEN PDCD12 ENSG00000169857 "Apoptosis and caspase activation inhibitor" Q9NQS1 15 33858782-34075155 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 44.0;Oligodendrocytes: 86.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.3" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020863 Approved Approved "Plasma membrane,Actin filaments,Centrosome" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Actin filaments" Centrosome "HPA020863: AB_1845219" "unprognostic (1.54e-3)" "unprognostic (1.99e-1)" "unprognostic (8.93e-2)" "unprognostic (5.77e-2)" "unprognostic (5.57e-2)" "unprognostic (2.05e-1)" "unprognostic (1.18e-1)" "unprognostic (6.32e-3)" "unprognostic (1.70e-1)" "unprognostic (1.40e-1)" "unprognostic (4.14e-3)" "unprognostic (1.79e-1)" "prognostic unfavorable (5.29e-10)" "unprognostic (7.66e-3)" "unprognostic (2.40e-1)" "unprognostic (1.63e-1)" "unprognostic (2.84e-3)" 13.7 11.4 8.5 7.2 8.6 4.4 10.8 8.9 10.1 11.4 10.5 15.2 7.4 12.5 5.2 12.3 11.3 6.4 28.5 8.2 9.2 5.5 16.9 7.2 4.8 9.2 9.0 10.5 20.8 3.0 5.8 12.4 9.4 9.4 9.4 2.5 7.9 9.1 31.1 11.2 7.5 12.5 8.8 6.5 12.3 10.7 9.0 6.9 5.6 13.6 7.9 16.2 10.8 9.1 16.4 26.3 26.0 8.6 21.4 24.1 14.7 41.1 36.2 31.9 19.9 7.2 11.3 15.2 24.8 34.8 24.2 10.4 12.2 26.9 25.7 14.6 7.7 26.1 15.9 20.5 31.5 26.6 18.2 19.8 50.9 18.4 45.8 38.6 35.2 7.6 26.6 21.1 45.6 17.3 10.5 46.1 11.9 22.2 8.5 15.7 14.6 32.2 26.4 21.0 13.4 16.8 22.6 11.6 11.4 10.7 12.6 29.4 24.5 27.7 9.5 12.0 34.6 21.2 17.7 31.1 13.3 31.0 15.2 0.0 0.2 0.0 0.5 0.6 0.6 0.4 0.5 0.2 0.2 0.1 0.2 0.3 0.0 0.5 0.2 2.3 0.9 0.1 8.5 8.6 8.9 10.1 8.2 9.2 9.2 9.0 9.4 8.8 9.0 9.1 9.0 3.2 5.3 16.6 5.6 5.7 8.7 1.8 3.4 5.6 7.5 9.0 32.7 2.8 0.8 0.0 6.2 11.0 10.5 7.4 0.0 2.9 13.8 4.4 14.3 10.2 4.8 9.5 21.8 8.6 44.0 8.5 5.6 5.6 0.0 14.7 8.6 19.1 7.4 8.4 24.1 7.7 0.0 4.1 4.4 6.5 7.5 5.0 3.6 22.5 3.5 10.9 7.2 26.7 86.6 7.0 5.2 10.5 15.6 21.5 9.4 4.6 1.5 5.3 6.6 4.9 9.7 6.2 7.4 12.9 9.7 9.4 6.5 23.1 6.0 14.7 AXL "ARK, JTK11, Tyro7, UFO" ENSG00000167601 "AXL receptor tyrosine kinase" P30530 19 41219223-41261766 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Differentiation, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Oncogene, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 147.2;Kupffer cells: 187.5;Langerhans cells: 185.5;Prostatic glandular cells: 123.4;Sertoli cells: 210.4;Smooth muscle cells: 171.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 11.1;plasmacytoid DC: 25.7" "Group enriched" "Detected in many" 12 "dendritic cells: 25.7;NK-cells: 11.1" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 501.2;U-251 MG: 540.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032501, HPA037422, HPA037423, HPA075217" Uncertain Supported "Vesicles,Plasma membrane,Actin filaments" NA Yes 12100000 72000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "Vesicles, Actin filaments" "CAB032501: AB_2062572, HPA037422: AB_10672347, HPA037423: AB_2675470, HPA075217: " "unprognostic (2.20e-1)" "unprognostic (2.02e-1)" "unprognostic (6.79e-3)" "unprognostic (1.01e-1)" "unprognostic (1.40e-1)" "unprognostic (8.49e-3)" "unprognostic (2.42e-1)" "unprognostic (1.74e-1)" "unprognostic (3.15e-2)" "unprognostic (2.82e-2)" "unprognostic (9.57e-3)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.53e-7)" "unprognostic (1.16e-3)" "unprognostic (1.52e-2)" "unprognostic (5.56e-2)" "unprognostic (4.83e-3)" 43.6 18.8 17.5 15.5 22.6 1.7 26.6 19.7 17.7 36.1 12.4 42.5 11.7 34.4 8.7 17.6 25.4 22.4 26.7 16.6 18.8 9.8 15.0 25.9 6.2 26.8 20.6 24.7 6.3 10.7 7.3 34.2 22.1 19.2 12.6 5.8 10.6 24.6 9.4 20.0 19.0 37.1 20.9 37.7 21.4 18.6 24.0 7.2 16.6 11.3 5.0 32.5 25.2 21.9 408.0 160.0 9.7 1.3 34.6 34.7 0.5 314.5 280.2 450.9 278.2 8.5 185.5 0.2 124.7 501.2 235.3 33.3 0.4 211.8 384.8 0.7 0.3 0.0 100.4 6.3 125.0 0.3 0.3 26.4 3.8 266.7 409.5 254.8 169.8 0.1 15.8 0.5 284.6 0.5 0.2 0.4 4.1 1.0 76.3 0.2 165.3 0.3 202.3 0.2 0.1 0.1 81.5 0.6 1.8 57.4 0.9 7.2 351.8 317.8 214.6 307.7 540.8 0.5 0.9 1.0 211.5 0.5 241.8 1.5 0.3 0.2 0.1 0.4 0.2 0.1 0.3 0.1 6.0 0.1 0.3 0.3 0.3 11.1 0.2 25.7 0.4 0.3 17.5 22.6 19.7 17.7 16.6 18.8 26.8 20.6 22.1 20.9 24.0 21.9 13.5 9.6 3.6 35.9 1.9 41.7 88.3 10.3 3.4 0.5 2.3 14.2 8.6 1.5 4.4 5.5 0.0 4.2 0.8 0.1 0.0 6.9 8.7 6.0 45.8 17.7 0.0 0.0 0.8 0.2 2.1 147.2 1.5 5.4 0.0 17.3 11.0 1.2 28.8 1.7 1.1 0.1 2.0 187.5 185.5 5.5 61.5 61.4 26.6 30.9 3.1 26.8 0.0 11.1 0.5 14.5 0.1 79.7 0.8 123.4 0.3 0.1 2.8 1.2 210.4 38.1 171.1 1.9 2.0 1.2 29.1 11.5 3.6 2.5 0.1 28.0 BICDL2 CCDC64B ENSG00000162069 "BICD family like cargo adaptor 2" A1A5D9 16 3027682-3036944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 104.8;pancreas: 127.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 52.2;Breast myoepithelial cells: 22.1;Ductal cells: 34.3;Endometrial ciliated cells: 28.9;Exocrine glandular cells: 49.8;Glandular and luminal cells: 28.3;Pancreatic endocrine cells: 35.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 9.0;BEWO: 15.4;CAPAN-2: 14.4;HaCaT: 22.5;MCF7: 22.8;RT4: 10.8;SK-BR-3: 11.0;T-47d: 14.0" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 2.7" HPA043251 Approved Approved "Intermediate filaments,Actin filaments,Cytosol" No NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 30: Mammary glandular cells - Lactation" "Intermediate filaments, Actin filaments, Cytosol" "HPA043251: AB_10794925" "unprognostic (2.00e-1)" "unprognostic (5.37e-2)" "unprognostic (1.71e-1)" "unprognostic (6.06e-3)" "unprognostic (9.65e-5)" "unprognostic (5.79e-3)" "unprognostic (6.47e-2)" "unprognostic (1.75e-2)" "unprognostic (2.45e-1)" "unprognostic (1.66e-2)" "unprognostic (2.05e-2)" "unprognostic (4.71e-2)" "unprognostic (8.56e-2)" "unprognostic (2.55e-2)" "unprognostic (2.38e-1)" "unprognostic (4.32e-2)" "prognostic favorable (9.04e-4)" 0.4 0.0 0.2 1.9 0.2 0.0 8.6 0.4 0.4 20.7 0.1 25.1 10.4 0.7 2.6 104.8 6.0 3.4 0.0 0.2 0.1 5.8 0.9 5.9 0.0 0.6 0.3 0.1 127.2 4.1 1.5 0.3 0.8 16.8 6.4 0.0 44.4 3.2 0.6 43.8 13.5 0.2 0.2 0.2 21.5 0.1 0.3 0.2 6.1 0.0 3.1 11.4 44.3 0.2 9.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 2.6 14.4 0.0 0.0 0.0 0.0 22.5 0.0 0.4 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.1 0.0 6.4 0.0 0.1 0.0 0.2 0.0 10.8 0.2 0.1 0.0 11.0 0.0 0.3 14.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.4 0.4 0.2 0.1 0.6 0.3 0.8 0.2 0.3 0.2 0.3 12.8 18.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 52.2 22.1 0.0 0.0 12.4 16.5 0.0 4.5 1.3 0.0 3.9 34.3 0.0 28.9 2.8 0.5 0.0 0.0 0.0 49.8 6.1 0.6 0.0 28.3 2.5 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 35.8 0.0 0.0 0.1 0.0 0.0 0.2 12.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.5 0.6 0.3 0.0 0.0 BZW2 "HSPC028, MST017, MSTP017" ENSG00000136261 "Basic leucine zipper and W2 domains 2" Q9Y6E2 7 16646131-16706523 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 265.5;skeletal muscle: 367.7;tongue: 258.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 278.2;Extravillous trophoblasts: 875.6;Syncytiotrophoblasts: 762.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022813, HPA026709" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Actin filaments, Cytosol" "HPA022813: AB_1845511, HPA026709: AB_10600752" "unprognostic (2.27e-3)" "unprognostic (1.77e-3)" "unprognostic (5.91e-2)" "unprognostic (4.79e-3)" "unprognostic (2.80e-2)" "unprognostic (7.08e-3)" "prognostic unfavorable (7.86e-8)" "unprognostic (9.13e-3)" "unprognostic (8.49e-3)" "unprognostic (2.81e-2)" "unprognostic (1.83e-3)" "unprognostic (3.37e-2)" "prognostic unfavorable (6.01e-4)" "unprognostic (1.00e-1)" "unprognostic (1.66e-1)" "unprognostic (6.77e-2)" "unprognostic (1.25e-1)" 26.1 18.1 8.5 26.8 10.1 45.7 49.7 6.9 14.3 19.1 9.7 51.2 28.9 18.4 9.9 42.6 20.2 17.2 265.5 10.2 6.3 37.8 18.4 20.0 30.0 5.2 6.3 16.0 30.0 6.7 10.4 80.4 6.5 19.3 56.8 88.0 23.8 34.3 367.7 55.5 30.0 39.0 5.6 16.5 50.2 11.6 6.9 33.0 36.5 258.9 38.4 59.5 26.2 8.8 91.7 81.3 138.2 201.7 67.5 118.3 125.7 126.0 156.3 117.6 124.9 201.8 129.7 208.0 143.7 96.9 87.6 181.6 164.8 141.5 152.0 27.8 99.8 129.6 84.4 117.0 70.5 180.3 79.1 90.6 74.6 104.0 187.7 92.4 171.6 149.7 251.9 43.5 96.9 105.0 90.0 210.4 143.9 259.5 174.1 111.0 91.2 216.6 113.4 152.6 179.9 106.8 50.8 419.9 67.7 156.7 187.8 149.5 97.6 93.1 119.1 141.5 136.3 89.5 92.8 288.1 45.5 220.6 340.3 2.6 46.0 5.0 27.3 55.2 44.6 44.6 39.8 36.9 98.8 42.9 56.8 47.1 2.1 56.8 41.6 38.5 31.8 44.0 8.5 10.1 6.9 14.3 10.2 6.3 5.2 6.3 6.5 5.6 6.9 8.8 32.8 22.4 60.5 3.9 30.0 57.6 69.9 60.5 82.6 55.9 52.3 57.0 278.2 17.2 53.9 47.8 64.6 214.3 26.8 42.4 58.7 47.5 9.8 31.9 43.2 42.9 30.5 63.5 48.6 65.6 875.6 43.5 110.1 40.6 21.0 33.3 8.9 13.7 65.0 6.7 32.0 49.5 61.1 33.4 46.0 6.4 12.2 30.7 24.9 12.2 47.5 19.7 19.6 19.1 17.9 47.0 42.9 9.8 31.9 52.0 19.2 20.8 32.6 106.4 6.6 30.2 54.2 11.3 4.1 99.6 51.6 762.9 29.3 52.6 90.6 79.0 CACNA1E "BII, CACH6, CACNL1A6, Cav2.3" ENSG00000198216 "Calcium voltage-gated channel subunit alpha1 E" Q15878 1 181317690-181808084 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "brain: 42.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 188.7;Inhibitory neurons: 116.0;Oligodendrocyte precursor cells: 73.9;Oligodendrocytes: 34.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.6;NB-4: 1.0;NTERA-2: 1.1;U-266/70: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042515, CAB079032" Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Actin filaments, Cytosol" "CAB079032: , HPA042515: " "unprognostic (3.96e-3)" "unprognostic (1.89e-1)" "unprognostic (1.05e-2)" "unprognostic (1.54e-5)" "unprognostic (6.56e-2)" "unprognostic (3.16e-2)" "unprognostic (4.30e-3)" "unprognostic (1.18e-1)" "unprognostic (2.40e-1)" "unprognostic (9.48e-3)" "unprognostic (1.04e-1)" "unprognostic (2.06e-1)" "unprognostic (9.85e-7)" "unprognostic (1.74e-2)" "unprognostic (2.07e-2)" "unprognostic (1.16e-1)" "unprognostic (3.75e-2)" 0.0 1.0 33.5 0.6 30.5 1.2 0.0 0.0 34.6 0.0 0.0 0.1 0.0 0.0 1.5 0.2 0.7 0.0 0.3 42.8 3.4 1.3 0.0 0.1 0.4 4.6 6.2 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.2 0.2 9.7 0.4 0.1 1.0 3.8 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.1 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 33.5 30.5 0.0 34.6 42.8 3.4 4.6 6.2 0.9 9.7 3.8 1.1 0.0 0.0 0.0 3.6 0.0 0.1 0.0 0.0 0.0 4.6 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.4 0.0 0.0 188.7 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 116.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 6.5 0.0 0.2 0.0 73.9 34.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.0 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 CCDC69 "DKFZP434C171, FLJ13705" ENSG00000198624 "Coiled-coil domain containing 69" A6NI79 5 151181052-151224093 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 351.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 124.5;dendritic cells: 106.9;Granulosa cells: 138.2;NK-cells: 197.8;Plasma cells: 133.6;Theca cells: 132.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 129.2;Daudi: 199.9;U-266/70: 120.5;U-698: 119.1" "Region enhanced" "Detected in some" "cerebellum: 4.8" "Low region specificity" "Detected in all" "HPA043648, HPA052896" Uncertain Approved "Golgi apparatus,Plasma membrane,Actin filaments" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "Golgi apparatus, Actin filaments" "HPA043648: AB_10795877, HPA052896: AB_2681983" "prognostic favorable (3.21e-4)" "unprognostic (2.60e-2)" "unprognostic (1.28e-1)" "unprognostic (2.78e-2)" "unprognostic (5.62e-2)" "unprognostic (8.63e-3)" "unprognostic (3.07e-2)" "unprognostic (6.48e-2)" "unprognostic (2.00e-1)" "unprognostic (9.29e-2)" "unprognostic (3.85e-2)" "unprognostic (1.55e-2)" "unprognostic (3.67e-1)" "unprognostic (4.31e-2)" "unprognostic (3.69e-1)" "unprognostic (2.93e-1)" "unprognostic (2.01e-1)" 108.9 89.6 6.7 45.8 8.4 46.3 60.5 12.2 7.9 15.2 13.4 138.5 19.6 32.9 13.3 54.1 37.1 19.3 96.9 5.9 8.9 10.7 24.0 39.0 70.4 13.3 13.8 27.1 47.5 32.1 8.5 14.8 13.6 23.0 20.5 1.8 14.4 29.4 351.9 13.3 44.7 45.6 11.3 55.4 37.0 13.2 9.2 37.8 11.6 163.8 66.8 87.7 21.9 7.2 8.0 1.6 0.4 6.4 129.2 13.1 4.2 1.5 13.1 2.6 2.4 2.1 1.1 199.9 6.3 0.5 3.3 1.0 3.0 2.8 0.9 0.1 2.7 27.0 0.0 17.5 21.1 9.9 34.4 33.0 0.2 1.0 0.0 2.5 13.1 0.0 23.7 44.0 0.1 0.6 43.8 23.3 7.5 0.1 15.2 36.0 1.0 12.1 0.5 5.9 0.2 0.8 2.4 3.2 1.7 3.2 2.0 24.0 32.0 1.0 6.1 0.6 1.5 120.5 60.1 119.1 1.4 22.2 0.0 30.9 12.4 13.5 11.3 10.9 10.3 5.4 8.8 10.8 10.0 10.4 6.1 6.6 9.6 14.3 10.3 19.3 8.5 11.5 6.7 8.4 12.2 7.9 5.9 8.9 13.3 13.8 13.6 11.3 9.2 7.2 51.0 12.8 78.4 0.7 68.8 2.5 3.0 3.5 1.2 0.4 4.8 2.4 124.5 1.5 13.5 1.8 0.0 7.3 106.9 0.2 0.0 2.9 0.5 26.8 2.7 58.9 1.8 32.2 1.8 20.0 9.6 18.4 7.1 1.3 34.8 138.2 28.2 39.7 7.3 6.7 2.7 0.0 4.1 64.0 12.2 2.4 5.6 46.5 10.6 11.2 73.5 4.9 197.8 1.0 0.6 8.8 0.1 7.9 133.6 3.6 4.5 3.2 51.3 1.4 13.1 4.7 14.8 1.2 1.0 0.7 1.3 35.4 65.7 132.1 0.9 23.5 CCDC71L "C7orf74, FLJ36031" ENSG00000253276 "Coiled-coil domain containing 71 like" Q8N9Z2 7 106654360-106661158 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 78.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067925 Approved Approved "Golgi apparatus,Actin filaments,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Actin filaments" Cytosol "HPA067925: AB_2685925" "unprognostic (1.51e-1)" "prognostic unfavorable (9.08e-4)" "unprognostic (7.26e-2)" "unprognostic (1.10e-2)" "unprognostic (1.78e-2)" "unprognostic (1.95e-3)" "unprognostic (9.94e-2)" "unprognostic (1.74e-1)" "unprognostic (1.60e-1)" "unprognostic (2.38e-3)" "unprognostic (6.03e-2)" "unprognostic (2.83e-1)" "prognostic unfavorable (2.53e-6)" "unprognostic (3.34e-2)" "unprognostic (3.72e-1)" "unprognostic (2.26e-1)" "unprognostic (6.35e-2)" 51.5 9.8 2.7 19.6 2.7 15.8 18.7 2.0 2.9 13.1 3.3 14.6 6.5 16.9 2.8 6.8 36.2 10.8 8.2 2.9 3.2 18.1 46.7 22.1 9.6 8.2 2.8 10.1 9.3 5.2 6.4 3.7 3.7 11.2 5.4 1.0 12.6 6.6 5.3 6.2 15.8 7.2 3.3 18.7 16.3 6.9 4.6 14.5 10.2 2.5 8.0 40.0 9.3 3.6 24.8 5.1 7.4 8.9 16.3 15.4 0.0 37.0 47.5 14.2 15.4 0.7 15.3 16.5 12.6 63.3 27.1 2.8 3.6 10.7 11.7 38.7 8.5 2.1 0.9 0.0 25.5 8.4 19.4 13.2 6.4 6.5 3.7 24.1 50.0 9.2 56.0 39.9 17.1 7.1 11.5 13.3 16.0 2.0 17.0 15.4 2.1 3.3 7.3 1.4 3.2 22.1 23.9 8.6 55.9 15.4 3.9 10.1 22.0 31.4 2.9 3.7 14.6 38.4 3.8 13.5 24.3 10.8 35.3 4.9 0.6 1.8 1.1 0.4 0.8 1.3 0.8 0.8 0.4 0.9 0.4 0.6 4.1 0.6 0.7 1.4 1.7 0.5 2.7 2.7 2.0 2.9 2.9 3.2 8.2 2.8 3.7 3.3 4.6 3.6 44.0 3.2 11.6 1.0 9.4 8.2 50.5 2.1 6.8 4.3 39.9 33.0 6.2 18.6 1.6 5.5 2.1 3.0 26.2 12.9 11.7 7.4 1.2 18.7 78.7 21.4 6.6 11.6 1.8 10.7 7.4 47.8 3.6 20.2 12.0 3.3 45.7 34.4 8.1 6.7 2.8 7.3 4.1 10.0 13.9 2.1 21.8 22.5 12.4 1.9 6.5 5.0 10.3 2.5 1.8 13.9 10.1 17.7 4.3 11.0 10.1 4.7 6.8 4.8 0.0 24.5 30.1 7.1 4.9 4.0 5.1 3.3 13.7 3.4 9.5 18.3 CD274 "B7-H, B7-H1, B7H1, PD-L1, PDCD1LG1, PDL1" ENSG00000120217 "CD274 molecule" Q9NZQ7 9 5450503-5470566 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 16.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 27.7;granulocytes: 28.4;Langerhans cells: 50.9;monocytes: 42.4;Syncytiotrophoblasts: 44.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 6.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.6" "Cell line enhanced" "Detected in many" "HDLM-2: 89.6;HHSteC: 55.5;U-251 MG: 98.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003528, CAB076385" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane, Actin filaments" Nucleoplasm "CAB076385: AB_2687655, HPA003528: " "prognostic favorable (8.89e-4)" "unprognostic (4.54e-2)" "prognostic favorable (1.64e-5)" "unprognostic (1.27e-2)" "unprognostic (2.96e-2)" "unprognostic (1.08e-1)" "unprognostic (4.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.68e-2)" "unprognostic (5.67e-4)" "unprognostic (7.39e-3)" "unprognostic (1.69e-2)" "unprognostic (1.24e-2)" "unprognostic (1.35e-1)" "unprognostic (1.49e-2)" "unprognostic (2.67e-1)" "unprognostic (9.02e-2)" 2.6 2.0 1.0 10.3 0.9 1.9 1.5 0.9 1.2 1.8 0.6 1.4 2.7 1.5 1.8 2.5 1.8 4.0 8.9 0.8 1.9 2.6 3.4 16.8 6.6 1.8 1.6 1.5 1.9 5.0 2.6 6.8 2.0 2.0 2.1 1.2 1.5 1.5 4.5 0.7 1.9 2.2 1.7 10.2 1.9 0.9 1.6 13.0 3.5 4.3 5.3 7.2 1.3 1.1 15.6 0.2 0.0 0.5 0.1 0.1 0.0 30.5 25.7 7.7 10.4 0.0 5.0 0.2 0.6 0.8 3.8 0.6 0.0 13.2 24.6 89.6 0.0 9.0 0.3 0.0 55.5 0.0 0.0 0.5 0.1 15.7 22.9 7.7 15.0 0.9 0.0 2.9 23.4 0.0 0.4 0.1 0.0 0.0 0.3 0.1 4.2 0.8 1.6 0.3 0.0 0.3 0.4 2.4 1.9 2.2 0.1 0.3 28.1 16.1 5.1 0.5 98.1 0.5 0.2 0.3 5.4 0.3 0.2 6.6 0.0 0.2 0.7 0.1 1.2 0.5 1.4 1.1 0.0 0.1 0.7 0.4 3.6 0.3 0.0 0.0 0.7 0.4 1.0 0.9 0.9 1.2 0.8 1.9 1.8 1.6 2.0 1.7 1.6 1.1 3.0 12.8 11.4 0.7 1.9 4.6 1.5 4.4 1.8 1.4 1.4 1.3 7.8 0.0 2.9 0.0 0.0 6.1 2.4 2.6 0.0 5.9 1.0 1.4 0.3 5.5 0.0 3.2 1.9 4.4 27.7 1.9 0.5 0.9 28.4 0.2 7.1 0.8 5.7 0.0 3.3 0.5 4.1 2.9 50.9 0.2 0.3 4.2 3.6 8.4 42.4 0.5 1.0 1.0 0.9 19.0 0.1 0.4 2.2 2.1 1.9 0.4 4.0 0.2 0.0 2.3 0.9 1.0 0.8 1.2 2.6 44.5 3.1 0.1 0.4 2.0 CDC42EP1 "Borg5, CEP1, MSE55" ENSG00000128283 "CDC42 effector protein 1" Q00587 22 37560480-37569405 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 245.6;Exocrine glandular cells: 226.0;Pancreatic endocrine cells: 266.2;Urothelial cells: 161.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 7.3;intermediate monocyte: 1.9;myeloid DC: 2.4" "Group enriched" "Detected in many" 10 "dendritic cells: 2.4;monocytes: 7.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006379, HPA076536" Approved Supported "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" "Nucleoplasm, Actin filaments" "HPA006379: AB_1078486, HPA076536: " "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (2.44e-1)" "unprognostic (3.79e-3)" "unprognostic (5.82e-2)" "unprognostic (4.06e-2)" "unprognostic (4.38e-2)" "unprognostic (5.57e-2)" "unprognostic (9.45e-2)" "unprognostic (1.63e-1)" "unprognostic (2.06e-2)" "unprognostic (1.53e-1)" "unprognostic (1.86e-2)" "unprognostic (2.85e-2)" "unprognostic (3.85e-2)" "unprognostic (3.81e-2)" "unprognostic (1.09e-3)" 76.3 91.2 55.7 16.7 107.5 1.6 58.0 89.9 73.3 68.2 17.6 43.7 31.1 70.7 4.1 93.1 61.0 40.8 53.8 55.9 67.3 50.2 133.1 65.2 11.3 102.8 104.5 60.9 161.6 16.5 18.8 31.8 97.4 41.5 14.4 2.6 102.7 23.9 13.1 71.2 32.7 19.6 70.2 26.2 155.9 23.6 87.5 2.7 33.7 11.1 10.4 38.4 69.6 151.5 125.2 35.4 15.1 67.9 23.7 40.2 73.3 69.9 41.0 78.9 54.3 87.8 15.9 0.2 24.2 81.4 25.4 95.0 17.8 35.1 26.0 15.5 60.7 0.5 33.9 53.6 167.7 0.3 0.6 74.9 52.1 65.0 61.5 63.1 59.2 0.1 78.9 0.7 33.0 42.6 0.3 0.5 13.6 96.5 79.6 0.4 27.5 2.4 27.9 1.9 0.4 2.6 51.2 112.3 112.4 20.6 50.3 11.0 91.6 163.9 98.2 80.0 98.6 0.2 0.8 0.3 65.3 0.7 135.6 0.4 7.3 0.0 0.1 1.9 0.1 0.0 0.1 0.1 2.4 0.3 0.0 0.2 0.2 0.4 0.1 0.3 0.0 3.4 55.7 107.5 89.9 73.3 55.9 67.3 102.8 104.5 97.4 70.2 87.5 151.5 62.4 6.4 19.5 2.3 1.8 46.9 87.2 51.4 21.1 0.1 59.2 31.8 3.5 134.4 41.1 12.9 0.0 98.2 2.0 41.6 1.9 245.6 3.7 4.3 20.0 54.7 11.5 0.0 0.1 226.0 110.3 32.1 133.0 9.0 2.5 1.7 69.7 35.6 13.2 1.7 0.2 66.6 30.5 5.9 29.3 1.7 39.4 5.3 21.4 4.7 8.9 12.8 0.0 2.0 42.7 266.2 45.8 35.3 0.6 122.4 17.5 11.4 14.7 0.3 39.5 22.8 49.5 2.0 0.6 55.9 52.0 112.2 2.2 7.0 61.1 161.3 CDC42EP4 "BORG4, CEP4, KAIA1777, MGC17125, MGC3740" ENSG00000179604 "CDC42 effector protein 4" Q9H3Q1 17 73283624-73312005 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Horizontal cells: 753.7;Muller glia cells: 570.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 20.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023335, HPA024797" Approved Supported Supported "Plasma membrane,Actin filaments,Microtubules" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "Actin filaments, Microtubules" "Plasma membrane" "HPA023335: AB_10603783, HPA024797: AB_10600696" "unprognostic (8.76e-2)" "unprognostic (4.38e-3)" "unprognostic (1.49e-2)" "unprognostic (5.43e-3)" "unprognostic (6.29e-2)" "unprognostic (9.01e-3)" "unprognostic (2.44e-3)" "unprognostic (1.08e-1)" "unprognostic (8.00e-2)" "unprognostic (2.41e-1)" "unprognostic (4.16e-2)" "unprognostic (6.73e-2)" "unprognostic (3.97e-1)" "unprognostic (1.66e-1)" "unprognostic (1.54e-1)" "unprognostic (1.10e-1)" "unprognostic (1.94e-1)" 94.5 54.9 84.9 15.3 84.7 14.9 74.5 90.6 76.3 47.4 75.0 55.6 35.7 52.7 60.1 33.3 69.4 19.1 50.5 82.2 103.1 28.6 32.2 38.6 16.1 141.9 104.5 70.7 77.5 20.5 45.0 22.9 83.7 38.7 17.4 98.1 41.5 43.1 28.8 40.6 36.0 25.5 103.5 24.1 42.4 20.5 105.9 20.2 45.4 18.8 27.6 33.8 39.5 109.5 30.1 70.1 24.7 20.9 48.8 40.5 65.0 26.2 32.6 24.3 17.9 14.8 42.1 0.1 22.9 31.6 27.6 20.6 17.2 18.0 14.6 1.4 17.0 6.7 35.2 34.7 24.3 1.1 7.3 51.4 14.9 21.2 10.5 19.2 27.9 0.6 18.9 1.4 14.9 23.2 1.2 8.6 13.5 87.8 48.4 0.8 11.0 3.1 28.8 34.3 16.4 24.8 19.7 53.1 18.4 19.0 64.3 9.8 28.7 22.7 47.6 18.1 18.9 1.4 1.2 0.2 37.3 4.7 60.7 3.3 3.2 5.9 0.1 8.5 0.2 0.1 0.0 0.0 4.3 0.0 0.2 0.0 5.4 0.3 20.1 0.1 0.0 2.1 84.9 84.7 90.6 76.3 82.2 103.1 141.9 104.5 83.7 103.5 105.9 109.5 117.1 12.8 15.6 54.9 2.8 48.7 58.5 54.9 97.9 11.5 45.8 37.1 10.8 31.5 29.1 12.9 6.2 32.1 2.5 47.3 11.7 29.4 0.6 29.7 47.6 43.8 31.2 9.1 1.0 43.6 35.0 46.1 31.1 41.2 13.3 19.6 42.8 27.7 6.1 753.7 1.3 41.3 14.2 5.5 30.1 2.7 18.3 9.1 30.2 6.5 11.1 570.4 0.0 2.5 2.5 30.4 33.5 15.4 2.5 42.6 53.1 8.0 18.0 26.2 131.5 98.0 69.9 1.1 2.0 83.2 44.9 84.3 6.0 13.6 30.2 124.1 CNN2 ENSG00000064666 "Calponin 2" Q99439 19 1026586-1039068 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 274.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049095 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA 8400000 "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 58: T-cells - T-cell receptor" Cytosol "Nucleoplasm, Actin filaments" "HPA049095: AB_2680627" "unprognostic (2.52e-2)" "unprognostic (2.69e-1)" "unprognostic (1.74e-1)" "unprognostic (4.49e-2)" "unprognostic (3.89e-1)" "unprognostic (5.31e-2)" "unprognostic (1.33e-1)" "unprognostic (2.56e-1)" "unprognostic (4.58e-2)" "unprognostic (6.56e-2)" "unprognostic (3.60e-2)" "unprognostic (3.33e-2)" "prognostic unfavorable (4.70e-7)" "unprognostic (1.28e-2)" "unprognostic (1.87e-1)" "unprognostic (2.50e-1)" "unprognostic (1.54e-1)" 76.7 22.1 6.3 149.8 7.9 208.8 82.1 9.0 11.2 88.2 30.3 64.1 25.6 118.0 20.0 131.7 88.7 78.8 60.2 6.1 6.7 65.0 42.9 152.2 184.2 9.5 7.7 164.7 69.2 8.6 22.4 37.8 9.6 84.1 33.6 7.5 89.4 68.4 8.1 76.5 64.8 56.0 7.9 154.0 75.1 12.1 9.0 52.2 79.0 7.7 169.9 86.4 79.7 13.3 230.7 75.6 206.9 257.3 104.5 196.9 162.6 204.3 221.8 249.2 192.5 263.0 191.8 151.2 203.9 367.9 58.9 221.3 123.9 324.1 164.7 104.7 10.6 109.6 122.0 205.9 415.0 97.4 230.1 337.2 150.9 158.1 118.5 405.6 142.9 110.1 64.0 225.2 206.0 44.0 8.9 91.5 256.2 184.0 35.0 52.8 72.5 170.9 247.5 265.9 0.5 14.8 252.6 34.3 27.5 149.6 247.6 163.6 349.4 134.8 140.0 210.0 208.9 105.2 86.8 297.8 79.6 117.7 220.9 560.2 142.2 631.5 243.1 180.6 393.5 231.0 301.6 324.2 217.5 201.9 250.1 252.0 845.4 213.8 209.4 96.7 347.3 393.3 6.3 7.9 9.0 11.2 6.1 6.7 9.5 7.7 9.6 7.9 9.0 13.3 10.3 60.9 60.6 0.0 140.4 97.6 274.2 142.9 178.2 1.2 36.5 66.4 6.1 15.7 78.4 36.8 10.4 12.0 66.4 47.0 62.6 63.6 0.5 29.1 52.9 26.3 15.4 44.1 0.1 138.6 99.8 50.4 49.5 40.0 59.5 44.3 37.9 29.8 54.9 0.0 0.1 51.2 42.7 87.9 103.1 1.8 8.1 90.7 14.2 2.8 129.9 0.9 91.6 0.0 0.6 186.9 27.1 76.8 85.8 60.9 3.3 5.9 37.8 7.5 32.9 10.4 70.6 1.7 3.8 135.0 87.8 11.4 160.8 1.7 32.1 170.9 CORIN "ATC2, CRN, Lrp4, PRSC, TMPRSS10" ENSG00000145244 "Corin, serine peptidase" Q9Y5Q5 4 47593999-47838106 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "heart muscle: 56.9" "Cell type enriched" "Detected in some" 6 "Cardiomyocytes: 69.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "ASC TERT1: 44.0" "Region enhanced" "Detected in some" "basal ganglia: 2.6" "Low region specificity" "Detected in some" HPA070941 Approved "Nuclear bodies,Plasma membrane,Actin filaments" "Intracellular and membrane" Yes No "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Nuclear bodies, Actin filaments" "HPA070941: AB_2686324" "unprognostic (1.05e-1)" "unprognostic (2.52e-1)" "unprognostic (1.14e-1)" "unprognostic (1.93e-1)" "unprognostic (2.10e-1)" "unprognostic (3.18e-1)" "unprognostic (3.58e-4)" "unprognostic (3.19e-1)" "unprognostic (3.67e-2)" "unprognostic (8.22e-2)" "unprognostic (9.78e-2)" "unprognostic (6.53e-2)" "unprognostic (1.18e-1)" "unprognostic (2.86e-2)" "unprognostic (5.18e-2)" "unprognostic (7.22e-2)" "unprognostic (1.33e-2)" 0.4 0.1 0.1 0.1 0.1 0.0 1.0 0.1 0.2 2.1 0.6 0.3 0.1 4.5 0.6 0.9 1.4 4.5 56.9 0.0 0.3 1.0 0.1 1.9 0.0 0.7 0.6 0.5 0.2 1.1 1.9 0.4 0.1 2.3 0.0 0.3 0.4 6.1 0.1 7.5 0.3 0.7 0.1 1.1 0.5 2.5 0.3 0.1 0.1 0.1 0.1 1.2 3.9 0.1 0.0 0.0 0.1 0.3 10.3 44.0 0.0 2.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 2.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.9 1.4 0.0 0.3 0.2 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.3 0.7 0.6 0.1 0.1 0.3 0.1 0.3 0.0 7.5 1.0 0.0 3.8 0.3 0.0 0.0 1.0 8.3 0.3 69.4 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.1 1.3 1.0 0.0 0.0 6.5 0.0 0.0 9.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 10.8 0.0 0.0 0.6 5.5 2.0 4.7 0.1 5.4 1.0 0.0 0.7 0.0 2.0 3.9 0.0 0.0 2.6 0.0 0.6 0.0 0.2 0.0 0.3 0.0 0.3 2.3 4.6 4.4 0.1 2.7 0.0 0.6 0.1 0.0 0.3 CRTAP "CASP, LEPREL3, P3H5" ENSG00000170275 "Cartilage associated protein" O75718 3 33114014-33147773 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 377.6" "Group enriched" "Detected in all" 5 "dendritic cells: 306.9;monocytes: 377.6" "Cell line enhanced" "Detected in all" "ASC diff: 795.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043598, HPA044150" Approved Approved "Intermediate filaments,Actin filaments,Cytosol" "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Intermediate filaments, Actin filaments, Cytosol" "HPA043598: AB_10960991, HPA044150: AB_10959594" "unprognostic (5.29e-2)" "unprognostic (2.64e-1)" "unprognostic (2.13e-1)" "unprognostic (1.85e-3)" "unprognostic (7.36e-2)" "unprognostic (4.73e-3)" "unprognostic (4.28e-2)" "unprognostic (1.87e-1)" "unprognostic (9.97e-2)" "unprognostic (4.62e-2)" "unprognostic (3.70e-1)" "unprognostic (1.40e-1)" "unprognostic (2.10e-1)" "unprognostic (1.41e-1)" "unprognostic (1.79e-1)" "unprognostic (9.93e-2)" "unprognostic (1.28e-3)" 157.2 106.5 65.2 38.7 69.2 43.2 123.9 51.9 54.8 211.2 52.9 145.1 35.0 170.1 57.1 58.7 138.3 80.5 83.9 49.6 64.9 67.9 44.6 92.3 37.3 65.2 62.4 131.4 36.0 45.7 22.8 69.9 63.9 90.7 51.6 19.3 54.0 106.5 54.4 84.1 65.6 115.0 67.5 48.2 78.9 25.0 65.3 23.7 77.2 68.9 38.1 142.7 135.8 69.5 64.1 123.3 37.8 119.2 795.0 516.6 219.0 136.1 294.0 160.6 151.9 42.1 35.1 44.4 147.6 259.3 129.9 80.2 68.0 103.9 115.5 110.1 106.0 69.2 87.6 43.7 237.4 45.4 54.8 415.3 208.5 145.0 183.2 311.7 172.0 27.0 60.3 82.1 164.6 54.7 16.5 46.3 45.5 67.5 165.7 59.4 111.0 86.1 127.8 42.0 7.9 61.0 92.0 79.8 201.1 87.3 85.9 109.3 113.0 209.1 89.1 115.4 145.9 59.0 214.3 6.7 164.3 89.7 117.1 13.4 377.6 28.5 35.8 147.7 52.5 39.9 51.4 40.2 306.9 39.2 29.2 27.8 30.5 42.1 46.0 82.5 74.0 200.5 65.2 69.2 51.9 54.8 49.6 64.9 65.2 62.4 63.9 67.5 65.3 69.5 74.0 9.6 42.8 15.3 29.0 60.4 41.1 39.5 150.8 17.9 32.7 43.7 34.7 25.8 22.0 38.6 8.4 49.0 37.1 14.8 11.7 25.0 1.2 17.4 135.7 72.7 6.0 46.0 10.0 32.0 81.6 142.3 29.0 31.2 48.1 58.4 122.4 53.2 107.0 35.3 14.5 26.0 10.2 181.1 91.1 6.3 142.9 108.6 80.0 10.3 134.1 15.9 22.6 17.1 11.6 18.4 16.3 144.8 58.1 24.5 24.4 52.7 6.8 10.1 111.7 78.4 120.9 1.6 15.9 95.1 46.7 28.0 26.5 89.9 36.1 30.0 DDIT4L "REDD2, Rtp801L" ENSG00000145358 "DNA damage inducible transcript 4 like" Q96D03 4 100185870-100190782 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "skeletal muscle: 323.5;tongue: 106.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 22.0;Distal tubular cells: 21.5;Extravillous trophoblasts: 18.5;Granulosa cells: 23.5;Sertoli cells: 19.7" "Cancer enhanced" "Detected in many" "testis cancer: 19.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 19.3;BJ: 29.6;fHDF/TERT166: 16.2;HSkMC: 14.7;hTERT-RPE1: 32.8;RPTEC TERT1: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050903 Uncertain "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane" "Nucleoplasm, Actin filaments" "HPA050903: " "unprognostic (2.21e-1)" "unprognostic (1.92e-1)" "unprognostic (1.34e-1)" "prognostic favorable (5.77e-4)" "unprognostic (1.66e-3)" "unprognostic (5.92e-2)" "unprognostic (2.72e-2)" "unprognostic (3.12e-1)" "unprognostic (3.21e-1)" "unprognostic (7.18e-2)" "unprognostic (2.59e-1)" "unprognostic (1.41e-1)" "unprognostic (4.47e-2)" "unprognostic (4.82e-3)" "unprognostic (2.09e-2)" "unprognostic (7.53e-5)" "unprognostic (4.99e-3)" 3.1 1.0 7.0 0.6 21.1 0.4 2.2 8.5 11.0 23.0 7.7 2.0 0.3 1.5 1.7 7.7 2.1 0.6 2.3 10.2 7.6 21.8 0.4 0.8 0.5 11.8 8.8 7.7 0.4 0.6 2.0 3.7 11.1 11.2 0.9 1.2 17.4 6.9 323.5 1.1 0.7 1.6 9.1 1.2 0.5 3.0 8.7 1.2 1.1 106.9 0.4 1.2 2.6 8.9 0.0 2.2 8.5 0.0 3.7 19.3 1.2 29.6 2.5 0.5 0.1 0.1 0.9 0.0 0.7 16.2 0.7 0.0 6.2 0.5 0.5 0.0 0.2 0.0 0.5 0.0 0.2 0.0 0.0 14.7 0.1 0.3 1.5 32.8 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 9.7 0.0 0.0 0.6 0.0 0.0 20.5 0.1 0.1 0.1 0.6 1.2 4.0 2.0 0.0 0.1 0.1 0.0 0.0 0.0 2.3 3.9 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 7.0 21.1 8.5 11.0 10.2 7.6 11.8 8.8 11.1 9.1 8.7 8.9 3.8 0.0 0.0 6.2 0.0 2.7 0.2 4.2 1.8 0.1 1.0 0.9 7.3 0.0 1.3 22.0 0.0 1.9 0.4 0.2 21.5 0.1 0.8 0.5 0.3 3.6 0.0 0.0 0.0 0.0 18.5 5.1 1.5 0.9 0.0 23.5 0.0 0.0 12.0 0.0 0.5 0.3 0.0 0.0 3.0 0.4 0.9 0.3 7.2 0.0 0.0 8.6 0.0 0.5 0.0 0.5 0.0 2.2 0.2 1.1 0.0 2.2 0.1 0.2 19.7 7.3 11.9 4.7 0.8 0.9 1.4 4.0 0.6 8.3 0.4 0.3 EFR3B "FLJ37871, KIAA0953" ENSG00000084710 "EFR3 homolog B" Q9Y2G0 2 25042076-25159135 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.1;skeletal muscle: 20.0" "Cell type enhanced" "Detected in many" "Astrocytes: 127.0;Excitatory neurons: 58.5;Inhibitory neurons: 110.7;Late spermatids: 46.0;Microglial cells: 54.4;Oligodendrocytes: 51.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.3" "Cell line enhanced" "Detected in many" "AN3-CA: 10.3;BEWO: 12.0;SH-SY5Y: 10.7;SK-BR-3: 18.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038089, HPA071831" Uncertain Supported "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 10: Brain - Neuronal signaling" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Actin filaments, Cytosol" "HPA038089: AB_10672618, HPA071831: " "unprognostic (9.31e-2)" "unprognostic (3.92e-1)" "unprognostic (2.10e-1)" "unprognostic (2.23e-1)" "unprognostic (1.90e-1)" "unprognostic (2.44e-2)" "unprognostic (1.24e-3)" "unprognostic (3.82e-1)" "unprognostic (3.42e-1)" "unprognostic (1.32e-2)" "unprognostic (4.49e-6)" "unprognostic (4.83e-2)" "unprognostic (4.43e-2)" "unprognostic (1.89e-1)" "unprognostic (2.46e-1)" "unprognostic (1.13e-1)" "unprognostic (1.55e-1)" 0.8 1.6 23.0 0.6 53.1 0.3 0.5 22.4 29.5 0.5 0.0 1.1 0.4 0.7 5.1 0.3 0.6 0.5 4.5 51.7 19.0 1.3 0.2 2.5 0.3 45.3 24.0 0.8 0.4 3.9 9.3 1.7 47.5 0.5 0.6 11.0 0.3 0.8 20.0 0.6 0.5 1.2 9.8 3.4 0.9 2.5 27.7 0.3 3.4 3.8 0.2 0.5 0.4 12.1 0.2 8.3 9.5 10.3 0.5 0.1 12.0 1.0 0.2 0.5 0.1 6.7 0.4 0.1 0.6 1.4 3.3 0.6 7.5 0.0 0.1 1.6 1.8 1.6 0.3 0.6 0.0 0.1 0.8 0.1 0.0 2.3 0.1 0.7 0.3 0.2 0.1 0.4 0.2 0.9 0.2 0.5 1.9 0.1 6.6 0.8 9.1 0.3 0.1 0.3 4.0 10.7 1.2 18.0 5.9 5.3 0.9 0.1 0.5 0.5 2.7 4.1 2.0 0.7 0.9 0.1 7.3 0.1 1.9 1.3 0.1 0.3 0.2 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.4 0.2 0.1 0.1 0.0 0.0 23.0 53.1 22.4 29.5 51.7 19.0 45.3 24.0 47.5 9.8 27.7 12.1 3.1 28.9 1.1 127.0 0.0 0.0 0.8 0.0 0.0 9.9 0.3 1.0 9.7 0.0 0.0 9.2 22.9 0.1 0.1 0.7 0.0 0.3 20.6 1.3 0.3 6.7 3.6 0.0 58.5 0.8 0.2 1.0 0.0 0.3 0.0 1.1 2.9 0.0 0.9 5.0 110.7 0.1 0.0 0.0 0.3 46.0 1.2 0.1 0.0 54.4 0.0 22.0 0.0 19.6 51.2 0.7 0.0 2.6 0.1 0.6 0.5 0.1 0.0 10.7 0.0 1.6 1.4 2.4 2.2 0.0 0.1 0.1 0.1 0.2 0.3 0.4 ENPP2 "ATX, PD-IALPHA, PDNP2" ENSG00000136960 "Ectonucleotide pyrophosphatase/phosphodiesterase 2" Q13822 8 119557086-119673453 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Lipid degradation, Lipid metabolism" Hydrolase "Cancer-related genes, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 383.3;choroid plexus: 753.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1041.6" "Cancer enhanced" "Detected in all" "renal cancer: 46.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 53.8" "Lineage enriched" "Detected in many" 8 "granulocytes: 53.8" "Cell line enhanced" "Detected in many" "AF22: 111.4;ASC diff: 147.7;ASC TERT1: 312.5;BJ: 103.2;BJ hTERT+: 188.9;fHDF/TERT166: 124.2;HSkMC: 144.7;U-2197: 108.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023700, HPA053652" Approved Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" NA NA 1200000000 "Cluster 46: Basophils - DNA binding" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Golgi apparatus" "Actin filaments" "HPA023700: AB_1848170, HPA053652: AB_2682218" "unprognostic (1.17e-2)" "unprognostic (6.29e-2)" "unprognostic (3.63e-2)" "unprognostic (3.93e-2)" "unprognostic (1.23e-1)" "unprognostic (1.37e-1)" "unprognostic (9.70e-3)" "unprognostic (7.14e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "prognostic favorable (2.07e-5)" "unprognostic (5.54e-2)" "unprognostic (3.14e-1)" "unprognostic (2.37e-1)" "unprognostic (5.18e-2)" "unprognostic (2.37e-2)" "unprognostic (1.50e-1)" 104.7 46.7 98.9 62.0 208.4 2.7 89.7 188.1 150.1 73.6 753.4 32.6 67.5 139.2 20.2 9.0 55.7 39.9 9.9 111.0 133.0 76.6 28.5 42.7 109.8 246.2 164.4 15.2 15.9 20.2 11.8 252.3 244.4 26.4 32.3 6.9 9.9 27.3 8.9 17.5 45.8 85.1 147.8 51.4 26.9 31.3 153.7 20.8 10.8 23.9 85.8 45.1 18.1 383.3 0.0 0.0 111.4 0.0 147.7 312.5 0.4 103.2 188.9 43.9 42.1 0.0 0.0 0.1 1.3 124.2 0.1 0.3 2.3 0.0 31.3 8.7 3.4 0.0 0.2 3.1 67.0 0.0 0.5 144.7 1.3 89.3 4.3 0.6 0.5 0.1 0.1 18.1 2.5 0.0 0.1 0.7 4.4 0.0 0.5 0.1 0.1 0.6 0.3 0.0 1.1 2.2 0.1 0.4 0.2 4.2 0.1 0.0 0.0 89.6 1.9 108.6 0.9 0.9 0.0 0.0 75.0 0.8 2.4 53.8 0.2 9.5 0.0 0.1 0.1 0.4 0.5 0.0 1.0 0.1 3.0 1.1 0.5 0.4 0.2 6.8 0.0 0.6 98.9 208.4 188.1 150.1 111.0 133.0 246.2 164.4 244.4 147.8 153.7 383.3 231.4 12.8 3.6 2.0 1.8 10.6 0.5 0.0 19.9 1.9 2.1 2.8 1.8 35.8 0.6 1.8 0.0 5.2 4.9 0.3 1.9 0.1 83.9 12.7 8.8 79.9 54.0 0.8 2.5 0.0 2.2 76.9 3.6 1.4 6.3 0.4 31.1 0.8 65.8 0.0 4.2 3.3 0.0 18.6 14.9 9.5 3.1 16.2 46.2 6.5 0.1 6.4 0.0 16.6 1041.6 0.7 2.6 3.4 1.9 0.1 4.2 47.6 3.7 1.2 0.0 3.1 9.6 1.7 0.4 7.8 5.3 6.4 1.7 1.1 2.8 1.4 FABP2 I-FABP ENSG00000145384 "Fatty acid binding protein 2" P12104 4 119317250-119322138 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 173 "intestine: 550.0" "Cell type enriched" "Detected in some" 10 "Proximal enterocytes: 5965.8" "Group enriched" "Detected in some" 9 "colorectal cancer: 3.2;pancreatic cancer: 1.6;stomach cancer: 2.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "basophil: 1.6;neutrophil: 4.2" "Lineage enriched" "Detected in single" 9 "granulocytes: 4.2" "Cell line enhanced" "Detected in some" "NB-4: 1.2;RPMI-8226: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA034607, CAB047325, CAB047326" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA 61000 "Cluster 1: Neutrophils - Mixed function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 45: Enterocytes - Digestion" "Actin filaments, Cytosol" "Plasma membrane" "CAB047325: , CAB047326: , HPA034607: AB_10601317" "unprognostic (3.94e-2)" "unprognostic (1.10e-1)" "unprognostic (1.05e-1)" "unprognostic (4.58e-1)" "unprognostic (1.51e-2)" "unprognostic (2.61e-2)" "unprognostic (1.69e-4)" "unprognostic (1.93e-1)" "unprognostic (1.02e-1)" 0.2 0.1 0.1 3.1 0.1 0.9 0.0 0.6 0.2 0.0 0.4 28.2 291.0 0.3 0.1 0.1 0.2 0.1 0.6 0.2 0.1 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 35.2 0.3 0.0 0.0 0.1 0.4 550.0 1.9 0.0 0.1 0.7 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 1.2 0.0 0.0 0.1 0.1 0.0 1.1 0.0 0.1 0.3 0.8 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.4 0.0 0.2 0.0 0.2 0.1 0.0 0.0 1.6 0.4 0.4 0.2 0.1 0.2 0.1 0.2 0.1 0.1 0.2 0.2 0.2 4.2 0.4 0.1 0.3 0.3 0.0 0.1 0.1 0.6 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.7 0.0 0.0 1.8 0.0 0.0 0.0 242.0 0.0 0.0 0.0 1.4 0.1 0.1 1.2 0.0 0.0 0.2 0.1 0.3 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 570.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 383.1 0.0 0.0 0.0 5965.8 17.3 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 222.5 0.0 FLNA "ABP-280, FLN, FLN1, OPD1, OPD2" ENSG00000196924 "Filamin A" P21333 X 154348524-154374634 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation" Actin-binding "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 1203.7;intestine: 1462.2" "Cell type enhanced" "Detected in many" "Peritubular cells: 500.6;Sertoli cells: 420.7;Smooth muscle cells: 459.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000356, HPA000368, HPA001016, HPA001115, HPA002925" Enhanced Approved Enhanced "Plasma membrane,Actin filaments,Cytosol" NA NA 730000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Actin filaments, Cytosol" "CAB000356: , HPA000368: AB_2797215, HPA001016: , HPA001115: AB_1078871, HPA002925: AB_1078869" "unprognostic (1.39e-1)" "unprognostic (9.40e-3)" "prognostic unfavorable (7.37e-4)" "unprognostic (3.68e-2)" "unprognostic (2.55e-1)" "unprognostic (6.05e-3)" "unprognostic (5.08e-2)" "unprognostic (1.08e-1)" "unprognostic (6.02e-2)" "unprognostic (1.30e-1)" "unprognostic (3.23e-2)" "unprognostic (9.58e-2)" "prognostic unfavorable (1.54e-6)" "unprognostic (5.49e-3)" "unprognostic (1.78e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (3.88e-4)" 267.4 55.9 14.4 223.2 18.5 157.9 164.2 15.2 43.0 392.1 54.7 1462.2 89.9 1203.7 35.5 454.7 609.4 137.9 108.4 14.8 23.0 70.5 21.2 238.9 65.0 39.9 19.9 236.7 50.5 13.4 30.5 79.2 24.4 369.2 86.9 9.0 80.3 617.2 49.7 124.7 354.6 706.6 21.1 102.7 508.0 33.7 34.0 48.1 85.6 31.2 38.1 1053.9 286.4 21.5 947.2 719.2 246.7 316.1 209.8 278.4 400.9 614.0 680.1 552.5 489.8 469.2 169.4 80.5 1551.4 966.4 970.1 528.3 224.0 538.1 152.7 333.6 77.8 262.2 914.9 159.7 375.9 309.3 324.9 266.1 126.1 825.5 327.0 533.8 417.1 94.9 74.7 538.7 401.3 210.7 148.5 93.1 258.3 97.9 470.9 147.8 221.2 71.6 197.2 193.4 52.9 119.7 515.8 80.2 381.1 187.3 79.1 96.3 1016.6 625.2 586.8 640.0 1147.1 333.7 212.8 162.3 580.3 202.4 638.7 7.6 24.9 11.8 32.6 23.1 21.2 10.2 15.6 29.2 22.4 4.6 6.0 14.3 3.6 10.5 34.2 2.7 20.7 56.2 14.4 18.5 15.2 43.0 14.8 23.0 39.9 19.9 24.4 21.1 34.0 21.5 105.1 57.7 38.7 30.0 76.9 124.3 85.9 127.8 85.4 3.5 40.9 153.5 34.5 38.6 26.1 35.0 0.0 24.6 257.7 2.6 1.9 272.0 2.1 33.8 186.3 107.0 1.8 39.7 11.8 133.1 90.9 137.9 13.3 55.8 26.0 334.5 81.8 4.3 120.3 11.8 8.6 2.5 22.4 141.0 263.0 13.7 122.4 227.7 88.9 30.9 207.9 39.4 270.8 8.0 2.6 347.4 1.5 500.6 98.7 96.1 1.9 3.0 9.1 4.3 420.7 118.3 459.3 4.1 8.9 48.8 73.6 20.0 172.3 134.7 3.3 35.3 GAS7 "KIAA0394, MGC1348" ENSG00000007237 "Growth arrest specific 7" O60861 17 9910606-10198606 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 133.6;Fibroblasts: 79.6;Inhibitory neurons: 76.6;Late spermatids: 73.4;Oligodendrocytes: 163.3" "Group enriched" "Detected in all" 4 "glioma: 15.7;melanoma: 54.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 26.2" "Group enriched" "Detected in many" 4 "granulocytes: 17.1;monocytes: 26.2" "Cell line enriched" "Detected in many" 9 "WM-115: 533.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004838, HPA064678" Enhanced Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 6: Brain - Smell perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Actin filaments, Focal adhesion sites" "HPA004838: AB_2667263, HPA064678: AB_2685319" "unprognostic (1.68e-2)" "unprognostic (2.84e-3)" "unprognostic (1.80e-1)" "unprognostic (1.28e-3)" "unprognostic (1.15e-1)" "unprognostic (1.01e-2)" "unprognostic (7.32e-2)" "unprognostic (7.16e-2)" "unprognostic (2.88e-1)" "unprognostic (1.50e-2)" "unprognostic (2.48e-1)" "unprognostic (1.79e-1)" "unprognostic (1.94e-3)" "unprognostic (6.48e-2)" "unprognostic (8.78e-2)" "unprognostic (3.08e-2)" "prognostic unfavorable (6.89e-4)" 27.3 8.5 34.9 23.7 68.9 31.1 15.3 75.4 79.8 29.9 0.0 26.3 7.3 13.3 4.3 23.8 17.8 16.3 46.1 61.9 8.4 1.7 2.3 17.1 9.1 23.4 24.1 7.8 3.4 1.1 2.6 16.2 15.8 8.5 12.0 30.1 7.8 10.8 5.8 33.7 11.9 24.0 14.3 16.1 8.9 17.4 32.9 9.3 4.6 6.8 10.3 18.3 19.5 85.3 0.1 0.5 0.6 1.0 16.5 22.5 0.3 0.8 0.0 2.6 1.1 0.1 0.2 6.6 1.9 6.6 0.3 0.3 0.0 0.0 1.6 0.0 1.5 0.0 1.3 0.7 5.3 1.8 48.7 4.3 0.3 5.1 0.1 0.0 0.0 42.7 0.0 0.6 0.0 0.0 54.3 15.4 2.6 2.1 0.0 14.3 0.1 49.6 0.0 0.2 0.1 3.0 0.2 0.2 60.1 21.0 2.8 24.7 0.0 0.2 3.4 0.1 0.1 0.4 0.0 0.0 0.4 35.1 533.8 0.6 26.2 17.1 2.8 6.9 0.9 0.5 0.3 1.4 5.3 0.6 0.2 1.4 16.4 4.5 4.9 1.0 0.0 7.7 34.9 68.9 75.4 79.8 61.9 8.4 23.4 24.1 15.8 14.3 32.9 85.3 2.9 0.0 4.2 6.8 3.3 8.3 4.5 1.5 1.2 34.6 1.6 2.3 13.3 0.0 1.1 5.5 27.1 1.0 14.5 0.0 0.0 1.0 62.3 17.7 12.8 5.7 0.0 0.4 133.6 0.0 1.8 79.6 0.0 26.3 17.2 7.9 5.0 0.9 39.2 0.0 76.6 0.0 0.0 66.7 32.2 73.4 10.2 54.3 33.8 52.5 57.2 9.5 18.6 11.1 163.3 0.2 0.0 1.9 5.5 2.0 0.0 0.1 16.3 31.7 0.0 67.0 7.1 1.6 6.7 1.0 16.6 1.9 7.4 0.2 0.0 4.9 GPR137 "C11orf4, GPR137A, TM7SF1L1" ENSG00000173264 "G protein-coupled receptor 137" Q96N19 11 64270062-64289500 "Predicted intracellular proteins, Predicted membrane proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 203.8" "Cell type enhanced" "Detected in all" "Early spermatids: 193.1;Late spermatids: 573.0;Spermatocytes: 175.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 14.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062871 Uncertain Approved "Nucleoplasm,Nucleoli,Actin filaments" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Nucleoli" "Actin filaments" "HPA062871: AB_2684889" "unprognostic (2.25e-1)" "unprognostic (4.21e-2)" "unprognostic (6.81e-2)" "unprognostic (1.06e-1)" "unprognostic (1.29e-3)" "unprognostic (6.37e-2)" "prognostic unfavorable (5.34e-4)" "unprognostic (5.68e-2)" "unprognostic (1.83e-2)" "unprognostic (7.61e-3)" "prognostic favorable (6.18e-4)" "unprognostic (4.95e-2)" "unprognostic (8.66e-3)" "unprognostic (3.67e-3)" "unprognostic (2.28e-1)" "unprognostic (2.13e-1)" "unprognostic (5.41e-1)" 20.6 32.6 54.4 16.4 50.9 13.7 19.6 49.4 63.8 24.5 42.5 22.6 12.2 23.6 12.6 28.9 22.3 15.0 29.1 52.8 44.3 34.0 33.9 19.4 14.9 55.3 50.5 18.7 16.2 23.2 26.5 15.6 56.2 29.1 7.5 11.8 23.7 14.8 16.8 22.5 19.5 10.4 45.9 24.5 27.4 203.8 56.2 10.6 30.8 15.9 12.8 26.7 21.4 48.2 22.0 50.2 18.6 49.5 34.9 19.9 69.6 25.5 24.3 31.0 18.4 38.0 31.6 22.7 42.4 24.1 51.9 44.3 28.8 17.1 9.7 73.0 27.9 22.7 53.7 22.5 21.6 15.0 40.9 24.8 25.0 27.5 19.0 20.8 16.3 28.4 20.6 56.2 19.1 56.9 16.8 40.5 22.5 20.4 49.9 31.0 18.0 37.5 20.0 30.3 27.2 32.6 30.0 44.6 30.6 21.4 46.0 6.3 23.1 69.1 46.8 53.3 18.7 41.9 84.9 20.5 50.0 12.3 44.9 1.9 2.8 5.1 2.3 2.5 2.9 2.7 2.0 1.7 3.0 3.8 2.1 1.8 14.0 1.9 2.1 3.0 1.6 1.4 54.4 50.9 49.4 63.8 52.8 44.3 55.3 50.5 56.2 45.9 56.2 48.2 13.0 3.2 11.2 12.7 15.0 14.4 18.5 21.8 19.4 14.1 16.2 13.3 5.3 20.0 13.7 12.9 12.5 49.6 9.5 26.2 15.6 39.0 193.1 14.4 14.8 15.8 16.2 14.7 9.3 26.6 69.7 13.4 15.3 10.0 2.5 10.3 11.4 10.8 23.2 20.2 9.0 16.8 14.2 15.4 14.5 573.0 19.3 11.5 14.2 6.5 16.4 38.9 11.3 4.5 11.2 30.8 14.6 16.1 13.4 26.7 31.5 19.6 18.6 9.1 26.3 8.7 14.1 175.0 55.9 16.9 15.2 119.6 10.8 16.6 15.1 23.3 GPX8 "EPLA847, UNQ847" ENSG00000164294 "Glutathione peroxidase 8 (putative)" Q8TED1 5 55160167-55167297 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 62.7;Extravillous trophoblasts: 218.9;Fibroblasts: 76.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 254.4;fHDF/TERT166: 246.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036720 Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "Actin filaments" "HPA036720: AB_2675269" "unprognostic (4.85e-2)" "unprognostic (1.23e-2)" "unprognostic (6.53e-2)" "unprognostic (1.92e-2)" "unprognostic (2.31e-2)" "unprognostic (9.74e-3)" "unprognostic (1.78e-2)" "unprognostic (1.63e-3)" "unprognostic (2.07e-2)" "unprognostic (4.34e-2)" "unprognostic (4.31e-2)" "unprognostic (8.68e-2)" "prognostic unfavorable (5.13e-9)" "prognostic unfavorable (7.96e-4)" "unprognostic (8.11e-2)" "unprognostic (1.16e-2)" "unprognostic (2.63e-2)" 13.3 6.1 1.2 12.5 1.2 0.1 12.6 1.2 1.6 37.1 6.9 7.3 2.9 21.1 21.9 6.2 14.3 17.0 11.2 1.0 1.7 6.5 2.2 6.9 3.8 1.5 1.1 27.3 4.6 9.3 2.4 39.7 1.4 10.2 8.4 1.3 7.2 15.8 1.5 5.0 4.1 27.2 1.5 4.0 5.6 5.6 1.2 1.3 22.3 6.3 3.0 17.8 9.8 3.6 37.2 39.0 75.3 77.0 180.7 223.9 36.6 179.8 254.4 97.0 192.7 3.2 82.1 0.0 199.0 246.4 86.5 28.2 46.0 51.5 131.5 0.5 17.3 2.1 49.1 6.9 64.4 0.0 0.0 157.5 60.8 68.3 35.5 126.5 122.7 0.0 1.1 0.1 137.4 14.4 0.0 0.0 32.6 1.0 42.8 0.1 40.2 0.0 65.9 1.3 0.1 1.4 56.6 4.6 68.0 80.8 56.6 3.4 102.7 63.6 65.6 84.5 102.3 0.1 0.5 0.5 103.0 0.1 118.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 1.2 1.2 1.6 1.0 1.7 1.5 1.1 1.4 1.5 1.2 3.6 10.9 0.0 1.1 0.3 0.3 7.1 6.0 38.3 9.1 0.2 8.9 6.1 4.3 0.0 33.3 25.8 0.0 49.5 0.2 0.5 5.9 13.7 0.4 6.5 62.7 18.6 0.0 0.0 0.1 38.8 218.9 76.6 2.6 4.9 4.5 30.9 19.2 0.2 10.2 0.0 0.1 4.7 4.1 0.0 6.9 0.6 51.3 1.1 24.9 5.6 1.1 7.9 0.0 0.0 0.1 15.8 0.3 39.9 1.4 2.6 0.1 0.5 36.5 0.3 13.1 20.1 38.2 0.1 0.4 3.1 6.1 13.3 1.8 29.9 0.9 2.4 GSC ENSG00000133937 "Goosecoid homeobox" P56915 14 94768223-94770113 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 3.8;breast: 6.8" "Cell type enhanced" "Detected in some" "Adipocytes: 3.5;Breast myoepithelial cells: 2.2;Ductal cells: 3.0;Exocrine glandular cells: 2.4;Fibroblasts: 9.2;Langerhans cells: 2.3;Skeletal myocytes: 2.6;Smooth muscle cells: 4.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 9 "hypothalamus: 1.4" "Immune cell enriched" "Detected in single" 8 "gdT-cell: 3.6" "Lineage enriched" "Detected in single" 18 "T-cells: 3.6" "Cell line enhanced" "Detected in some" "AN3-CA: 1.3;HEK 293: 2.0;MCF7: 3.2;REH: 3.3;SH-SY5Y: 3.5;T-47d: 2.5;U-251 MG: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB079923, CAB079924" Supported "Nucleoplasm,Nuclear speckles,Actin filaments" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: REH - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear speckles" "Actin filaments" "CAB079923: , CAB079924: " "unprognostic (2.11e-2)" "unprognostic (1.04e-1)" "unprognostic (3.15e-2)" "unprognostic (5.11e-2)" "unprognostic (2.49e-1)" "unprognostic (3.70e-3)" "unprognostic (1.82e-3)" "unprognostic (3.87e-2)" "unprognostic (3.41e-1)" "unprognostic (2.74e-1)" "unprognostic (1.39e-1)" "unprognostic (2.28e-1)" "unprognostic (5.18e-10)" "unprognostic (4.96e-2)" "unprognostic (1.31e-1)" "unprognostic (1.52e-1)" "unprognostic (1.16e-1)" 3.8 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.1 0.4 0.1 0.1 0.2 0.0 0.1 0.4 0.0 0.5 0.0 1.4 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.6 0.1 0.4 0.0 0.0 0.7 0.0 0.0 0.9 0.5 1.2 0.8 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.2 1.6 2.2 0.1 0.3 0.2 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.3 0.0 0.0 0.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 3.2 0.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.0 0.6 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.1 0.0 0.0 0.1 0.0 3.5 0.0 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.0 1.0 2.2 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 3.0 0.1 0.3 0.1 0.4 0.0 0.0 0.0 2.4 0.0 9.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.2 0.0 0.0 0.6 0.0 1.0 0.0 0.0 0.7 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 2.6 4.6 0.0 1.2 0.0 0.9 0.0 0.4 0.0 0.0 0.1 KCNK6 "K2p6.1, TWIK-2" ENSG00000099337 "Potassium two pore domain channel subfamily K member 6" Q9Y257 19 38319845-38332076 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 151.3;Urothelial cells: 131.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 26.2" "Group enriched" "Detected in many" 6 "dendritic cells: 11.4;granulocytes: 26.2;monocytes: 7.2" "Cell line enhanced" "Detected in many" "HEL: 37.6;HMC-1: 40.3;T-47d: 22.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB022637, HPA040184" Uncertain Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "Actin filaments" "CAB022637: , HPA040184: AB_2676876" "unprognostic (7.98e-2)" "unprognostic (2.57e-1)" "unprognostic (1.29e-1)" "prognostic favorable (1.45e-6)" "unprognostic (3.76e-1)" "unprognostic (6.88e-2)" "unprognostic (1.87e-1)" "unprognostic (3.08e-2)" "unprognostic (4.31e-1)" "unprognostic (4.91e-1)" "unprognostic (4.10e-3)" "unprognostic (3.15e-1)" "prognostic unfavorable (1.04e-5)" "unprognostic (1.07e-2)" "unprognostic (3.46e-1)" "unprognostic (5.88e-2)" "unprognostic (4.59e-3)" 3.9 2.4 2.9 7.5 2.4 3.9 5.6 3.0 3.3 29.9 2.7 15.4 4.6 24.0 1.5 30.5 15.7 4.5 6.7 2.7 2.2 3.1 3.0 9.4 5.6 2.9 2.3 9.5 12.5 0.6 1.9 7.0 2.9 6.2 9.4 0.8 14.5 2.4 1.5 19.1 6.8 14.3 2.1 15.6 9.5 2.1 2.8 2.5 1.4 0.7 7.9 13.3 18.2 3.7 9.2 3.3 0.5 0.5 5.1 3.3 0.7 7.8 3.8 2.0 2.7 2.6 9.8 0.6 3.5 11.2 2.1 11.7 4.2 17.7 1.3 0.4 0.3 37.6 1.9 0.4 4.7 2.7 40.3 0.8 15.6 2.5 4.8 10.5 5.3 5.8 0.5 2.8 5.7 20.2 2.4 2.3 0.4 19.4 2.1 3.9 0.5 2.7 7.1 0.8 0.5 0.8 0.8 0.8 0.3 1.8 22.8 10.5 5.8 0.5 4.4 4.1 0.4 1.0 0.2 1.0 0.6 13.4 0.3 26.2 6.9 15.8 1.4 6.2 1.2 1.4 2.0 1.9 11.4 1.1 1.7 1.2 5.0 0.6 7.2 3.1 2.6 2.3 2.9 2.4 3.0 3.3 2.7 2.2 2.9 2.3 2.9 2.1 2.8 3.7 8.7 0.0 10.5 0.0 16.0 43.1 50.6 20.6 20.5 3.3 61.2 32.9 12.1 17.2 15.1 7.3 6.2 2.0 18.5 62.4 0.0 19.1 2.8 32.5 58.8 28.3 12.6 17.9 1.1 47.7 4.0 19.2 28.1 84.8 22.2 72.7 151.3 4.3 39.2 0.0 1.7 64.5 2.0 75.7 61.5 1.2 25.7 47.0 5.4 2.8 62.1 1.2 11.3 0.0 0.9 67.2 39.2 20.3 45.6 41.1 37.6 0.4 7.7 5.9 26.3 3.1 9.3 14.8 3.3 48.0 67.2 2.5 14.8 1.5 26.7 131.5 KIF19 "FLJ37300, KIF19A" ENSG00000196169 "Kinesin family member 19" Q2TAC6 17 74326210-74355820 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 16.7;fallopian tube: 12.0;lymphoid tissue: 13.5" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 44.4;Enteroendocrine cells: 23.8;Hepatic stellate cells: 15.4;Intestinal goblet cells: 14.1;Plasma cells: 15.6;Respiratory ciliated cells: 57.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.1" "Lineage enriched" "Detected in single" 22 "T-cells: 2.1" "Cell line enriched" "Detected in single" 9 "SCLC-21H: 4.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043638, HPA073303" Enhanced Approved "Plasma membrane,Actin filaments,Centrosome" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" "Actin filaments, Centrosome" "HPA043638: AB_10962579, HPA073303: AB_2686593" "unprognostic (1.59e-3)" "unprognostic (1.05e-1)" "unprognostic (1.00e-1)" "unprognostic (5.37e-3)" "unprognostic (9.64e-2)" "unprognostic (1.64e-1)" "unprognostic (2.70e-2)" "unprognostic (2.81e-1)" "unprognostic (1.03e-1)" "unprognostic (9.83e-3)" "unprognostic (1.05e-3)" "unprognostic (1.14e-1)" "unprognostic (1.59e-9)" "unprognostic (5.16e-5)" "unprognostic (2.72e-1)" "unprognostic (1.67e-2)" "unprognostic (1.53e-1)" 1.4 0.1 7.5 0.4 10.3 0.2 1.2 4.0 11.4 2.2 3.5 1.7 3.0 0.3 0.0 0.5 12.0 0.4 0.3 7.2 7.4 0.2 0.9 1.9 0.1 7.5 8.0 0.2 1.1 0.0 0.3 0.0 5.9 0.9 0.6 0.1 1.0 0.2 0.4 0.6 2.3 0.4 6.2 13.5 0.7 0.6 7.7 1.0 1.9 0.6 0.1 1.6 1.5 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.2 0.0 0.3 0.6 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.4 7.5 10.3 4.0 11.4 7.2 7.4 7.5 8.0 5.9 6.2 7.7 16.7 1.3 0.0 0.0 2.0 1.3 0.0 0.4 2.5 0.0 1.1 0.1 0.0 1.6 0.0 6.3 0.0 0.0 0.0 3.5 0.8 0.0 0.0 0.5 44.4 0.2 4.2 23.8 0.4 0.0 0.0 3.1 1.0 1.1 0.7 0.0 0.0 15.4 0.1 0.1 0.0 0.1 14.1 4.1 0.6 1.6 0.3 0.0 0.3 3.6 0.0 0.1 5.7 3.1 4.0 3.7 0.0 0.1 0.0 15.6 0.3 0.2 0.0 57.6 0.3 0.0 1.8 1.3 0.2 1.6 0.0 0.1 0.0 2.5 0.2 1.9 0.2 KLC3 "KLC2L, KLCt, KNS2B" ENSG00000104892 "Kinesin light chain 3" Q6P597 19 45333434-45351520 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 26.1;skin 1: 104.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 142.0;Basal prostatic cells: 50.8;Ductal cells: 39.1;Prostatic glandular cells: 66.9;Suprabasal keratinocytes: 183.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 8.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 36.1;HaCaT: 16.2;HBEC3-KT: 10.5;hTCEpi: 12.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA052797, HPA056508" Approved Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Actin filaments" "Nucleoplasm, Cytosol" "HPA052797: AB_2681954, HPA056508: AB_2683159" "unprognostic (4.11e-2)" "unprognostic (3.71e-1)" "unprognostic (3.07e-4)" "prognostic unfavorable (1.46e-4)" "unprognostic (3.47e-3)" "unprognostic (1.13e-1)" "unprognostic (4.42e-2)" "unprognostic (2.29e-1)" "unprognostic (2.53e-1)" "unprognostic (1.75e-2)" "unprognostic (1.49e-1)" "unprognostic (2.74e-2)" "unprognostic (4.79e-3)" "unprognostic (1.94e-1)" "unprognostic (3.55e-3)" "unprognostic (4.14e-1)" "unprognostic (2.37e-1)" 0.3 0.2 0.5 0.3 1.1 3.0 3.3 1.3 0.8 10.0 0.0 0.1 0.1 0.2 2.1 26.1 0.3 0.2 0.2 0.4 0.2 5.9 0.2 0.9 0.3 0.5 0.0 0.2 4.0 4.0 2.7 0.2 0.2 2.6 0.2 1.0 11.6 1.0 0.9 104.1 0.3 0.0 0.0 0.3 0.5 3.7 0.2 1.0 0.7 0.0 1.8 0.2 20.5 0.7 36.1 0.2 0.2 0.4 0.1 0.1 2.8 0.2 0.0 0.0 0.1 3.5 6.5 0.3 2.8 0.0 3.7 16.2 2.2 10.5 0.2 0.8 5.3 0.1 1.1 0.7 0.0 0.3 2.2 0.0 12.9 0.1 2.5 0.4 0.0 0.5 0.6 0.4 0.1 4.7 0.1 0.4 0.8 0.6 1.1 5.6 0.0 0.3 0.3 1.3 4.5 0.7 0.3 7.3 1.0 0.4 6.5 0.1 0.0 0.4 3.6 0.3 0.4 0.7 0.8 0.3 0.2 0.2 0.4 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.2 0.2 0.2 0.4 0.2 0.2 0.2 0.1 0.0 0.5 1.1 1.3 0.8 0.4 0.2 0.5 0.0 0.2 0.0 0.2 0.7 0.2 0.0 2.4 0.3 0.0 142.0 50.8 17.5 14.8 0.8 10.3 25.3 0.4 2.8 7.3 1.8 0.0 0.2 0.2 0.2 9.8 39.1 3.0 0.9 0.3 1.7 0.0 2.7 0.3 3.1 0.7 1.4 0.0 2.4 0.0 6.7 0.4 0.0 0.3 1.7 0.4 0.5 6.1 0.0 10.9 12.0 1.8 0.4 14.2 0.0 0.8 0.7 0.0 0.0 0.0 11.8 0.0 0.4 0.0 66.9 0.0 1.4 3.8 2.0 0.0 1.1 2.5 0.6 11.3 25.6 183.3 0.7 1.0 0.0 0.1 22.0 LCP1 "CP64, L-PLASTIN, LC64P, PLS2" ENSG00000136167 "Lymphocyte cytosolic protein 1" P13796 13 46125920-46211871 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 709.0;epididymis: 402.7;lymphoid tissue: 605.1" "Cell type enhanced" "Detected in many" "dendritic cells: 438.4;granulocytes: 309.1;Hofbauer cells: 264.4;Kupffer cells: 401.2;Langerhans cells: 337.6;Late spermatids: 290.9;Macrophages: 466.1;monocytes: 535.7;NK-cells: 471.7;T-cells: 375.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 875.8;HDLM-2: 799.3;HL-60: 850.7;HMC-1: 861.7;JURKAT: 792.7;NB-4: 789.2;THP-1: 840.5;U-698: 1105.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019493, CAB020673" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA 1800000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "Actin filaments" "CAB020673: , HPA019493: AB_1855457" "unprognostic (2.79e-2)" "unprognostic (8.20e-3)" "unprognostic (1.19e-2)" "unprognostic (3.95e-3)" "unprognostic (1.19e-1)" "unprognostic (2.84e-2)" "unprognostic (2.70e-1)" "unprognostic (4.99e-2)" "unprognostic (6.70e-3)" "unprognostic (2.54e-1)" "unprognostic (5.47e-2)" "unprognostic (3.63e-1)" "unprognostic (3.32e-3)" "unprognostic (2.51e-1)" "unprognostic (1.02e-1)" "unprognostic (7.50e-2)" "unprognostic (2.92e-1)" 85.9 31.1 11.3 396.9 13.1 709.0 43.9 13.9 30.9 28.5 16.8 54.7 42.4 27.4 402.7 29.5 21.5 76.4 14.5 11.3 14.2 13.1 89.0 173.8 563.5 19.7 18.9 10.0 12.2 12.6 4.3 67.2 21.3 184.5 71.2 4.9 44.4 24.3 7.1 40.6 62.3 60.4 18.6 375.2 53.2 33.2 24.8 499.8 23.6 17.8 605.1 133.0 7.7 29.9 36.1 0.2 1.9 0.0 0.0 0.0 409.8 0.1 1.2 3.9 2.9 237.4 1.4 875.8 179.5 0.0 249.1 1.7 0.1 0.6 3.9 799.3 202.9 187.6 0.4 1.1 0.9 850.7 861.7 2.3 0.1 1.4 1.2 0.3 0.0 792.7 100.4 569.7 0.0 2.8 624.8 789.2 1.0 0.4 8.2 451.6 1.6 638.2 0.0 233.8 2.8 7.5 1.9 91.8 6.4 25.0 6.4 840.5 3.1 22.0 13.6 1.5 25.5 135.3 292.5 1105.7 17.0 530.9 3.6 1007.3 1559.5 810.8 915.7 1806.2 822.0 342.3 539.6 761.2 1134.5 251.6 330.2 560.5 1908.6 650.6 1826.1 297.5 598.1 3644.2 11.3 13.1 13.9 30.9 11.3 14.2 19.7 18.9 21.3 18.6 24.8 29.9 7.4 32.1 73.2 0.3 185.2 12.0 1.2 0.0 1.8 0.4 10.3 11.7 4.2 5.7 18.0 3.7 0.0 9.8 438.4 0.2 0.0 16.9 113.1 4.7 42.8 9.6 1.2 63.9 0.5 16.3 68.3 10.9 19.9 7.0 309.1 0.7 12.5 24.0 264.4 0.0 0.5 0.5 0.0 401.2 337.6 290.9 1.2 466.1 23.2 17.8 535.7 23.7 471.7 0.5 1.5 6.8 2.4 1.9 102.4 42.0 0.1 1.5 13.8 1.2 0.0 3.1 6.2 2.7 1.6 2.2 11.8 13.5 375.3 0.5 0.4 4.0 LMOD2 ENSG00000170807 "Leiomodin 2" Q6P5Q4 7 123655866-123664290 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 39 "heart muscle: 778.4;skeletal muscle: 933.7;tongue: 793.6" "Cell type enriched" "Detected in some" 26 "Cardiomyocytes: 1432.4" "Group enriched" "Detected in some" 20 "head and neck cancer: 3.5;prostate cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HSkMC: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA046370, HPA051039" Enhanced Uncertain "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Actin filaments, Cytosol" "HPA046370: , HPA051039: AB_2681321" "unprognostic (2.55e-1)" "unprognostic (1.14e-1)" "unprognostic (1.43e-1)" "unprognostic (2.38e-3)" "unprognostic (1.18e-1)" "unprognostic (5.50e-1)" "unprognostic (5.69e-2)" "unprognostic (6.98e-2)" "unprognostic (2.13e-2)" "unprognostic (1.43e-3)" "unprognostic (3.37e-2)" "unprognostic (1.51e-1)" "unprognostic (1.82e-3)" 0.2 0.1 0.0 0.0 0.0 0.6 0.5 0.1 0.5 0.0 0.2 0.1 0.0 0.0 0.0 21.2 0.0 0.1 778.4 0.2 0.0 0.0 0.2 0.3 0.3 0.0 0.1 0.1 0.2 0.0 0.1 0.8 0.0 10.2 0.0 0.1 10.0 0.0 933.7 0.4 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.2 793.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1432.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.4 0.5 0.4 9.4 0.0 0.0 0.1 0.0 0.1 27.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.9 7.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 LPIN2 KIAA0249 ENSG00000101577 "Lipin 2" Q92539 18 2916994-3013144 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transcription, Transcription regulation" Hydrolase "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 165.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 154.4;Granulosa cells: 323.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 7 "granulocytes: 23.4;NK-cells: 12.5;T-cells: 12.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015223, HPA017857, HPA030550" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Cytosol "Plasma membrane, Actin filaments" "CAB015223: , HPA017857: AB_1852904, HPA030550: AB_2673519" "unprognostic (7.03e-2)" "unprognostic (1.05e-1)" "unprognostic (2.88e-1)" "unprognostic (1.51e-3)" "unprognostic (1.20e-1)" "prognostic favorable (8.01e-4)" "unprognostic (9.85e-3)" "unprognostic (1.89e-2)" "unprognostic (1.03e-2)" "unprognostic (3.44e-3)" "unprognostic (3.19e-1)" "unprognostic (1.94e-1)" "unprognostic (3.15e-3)" "unprognostic (4.66e-2)" "unprognostic (2.21e-1)" "unprognostic (2.49e-1)" "unprognostic (7.11e-2)" 9.7 9.3 17.9 21.2 19.9 19.8 9.8 14.6 17.4 9.7 16.6 13.9 62.8 9.8 6.7 10.0 9.5 25.7 7.2 16.1 24.2 26.4 165.8 21.2 24.3 22.7 22.0 13.2 16.4 13.5 10.9 15.7 24.2 9.0 12.5 10.7 7.4 8.0 2.7 3.6 39.9 9.6 15.6 20.3 28.1 22.0 28.8 18.9 12.1 3.0 19.2 9.9 6.0 14.3 8.7 12.0 17.1 6.6 31.7 27.4 10.5 17.4 22.8 18.9 16.9 16.7 7.1 5.4 10.8 30.2 30.2 0.2 13.8 6.3 13.2 11.2 2.7 13.3 10.0 19.4 27.2 11.2 17.0 27.4 4.6 18.5 17.2 28.2 23.4 14.8 12.8 3.5 28.2 7.2 15.0 12.0 5.7 13.7 13.1 26.7 14.0 23.2 17.6 20.0 14.4 10.2 18.4 9.1 6.8 10.7 0.0 18.0 31.2 25.3 28.7 31.7 14.6 5.0 7.9 12.3 22.1 12.2 8.1 8.7 2.4 7.8 11.8 1.5 12.1 1.0 9.2 7.2 1.0 1.7 9.1 6.3 23.4 12.5 0.8 1.5 9.2 3.2 17.9 19.9 14.6 17.4 16.1 24.2 22.7 22.0 24.2 15.6 28.8 14.3 17.7 67.3 44.0 55.2 20.4 5.6 9.8 8.5 5.7 35.7 12.1 11.2 11.2 154.4 23.9 38.6 14.6 25.2 41.9 45.3 17.6 11.8 3.3 48.2 33.3 18.9 14.9 138.1 26.3 19.0 11.3 25.4 103.0 64.4 12.6 323.0 19.2 131.1 23.1 116.1 65.6 36.8 16.2 26.8 8.9 11.0 22.7 31.1 8.8 79.6 31.2 16.7 59.8 37.7 21.0 22.2 21.6 31.2 16.1 21.2 92.4 54.9 17.1 16.7 6.6 16.6 20.1 26.5 73.0 0.6 2.0 49.5 58.9 20.3 14.0 14.1 LRCH1 "CHDC1, KIAA1016" ENSG00000136141 "Leucine rich repeats and calponin homology domain containing 1" Q9Y2L9 13 46553168-46753040 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 89.2;Inhibitory neurons: 117.6;Microglial cells: 183.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 37.1" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021536 Approved Approved "Nucleoli,Actin filaments,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Actin filaments, Cytosol" Nucleoli "HPA021536: AB_1853258" "unprognostic (7.13e-3)" "prognostic unfavorable (6.24e-4)" "unprognostic (3.59e-2)" "unprognostic (8.93e-2)" "unprognostic (7.50e-2)" "unprognostic (1.37e-1)" "unprognostic (5.16e-2)" "prognostic unfavorable (6.67e-4)" "unprognostic (2.16e-1)" "prognostic unfavorable (5.75e-4)" "unprognostic (1.39e-2)" "unprognostic (1.17e-1)" "prognostic favorable (1.04e-4)" "unprognostic (2.87e-1)" "unprognostic (1.22e-1)" "unprognostic (3.39e-1)" "unprognostic (1.98e-2)" 15.1 5.0 4.7 10.7 4.7 8.9 14.6 37.1 6.2 15.9 4.2 15.2 7.9 16.3 7.7 10.0 11.8 12.6 8.4 5.7 6.1 14.9 12.2 13.8 16.3 6.5 7.0 10.1 5.6 5.4 5.8 18.2 7.8 10.8 10.0 10.3 10.0 12.0 3.9 17.9 11.6 17.6 7.9 14.6 13.0 4.6 6.8 18.5 6.5 7.5 15.7 13.5 9.7 7.5 7.4 10.4 9.2 9.6 6.6 12.5 23.6 12.4 16.1 15.0 14.2 23.5 12.3 23.4 3.4 11.7 9.8 10.4 7.1 12.5 21.6 24.2 6.6 21.0 4.3 11.1 8.2 13.8 34.5 7.9 9.7 13.9 16.8 12.3 13.1 15.6 4.2 6.9 11.2 14.2 14.8 17.3 5.2 46.3 5.5 8.0 10.0 6.3 28.1 7.5 14.5 14.6 7.0 6.8 18.8 16.2 5.3 18.3 12.5 8.8 6.0 11.0 11.9 1.3 3.7 10.6 10.3 11.9 10.8 0.6 0.9 0.9 1.5 0.7 0.8 2.2 1.1 1.0 0.8 2.7 0.8 0.9 0.3 2.5 0.5 1.0 0.8 0.9 4.7 4.7 37.1 6.2 5.7 6.1 6.5 7.0 7.8 7.9 6.8 7.5 61.5 6.4 6.1 24.8 26.7 37.5 10.5 6.2 27.3 8.3 12.0 11.8 7.2 17.2 6.5 22.0 22.9 13.4 8.4 6.8 9.8 8.3 1.6 5.4 6.5 32.5 1.8 9.9 89.2 4.2 12.7 14.3 18.8 13.7 27.9 2.8 17.5 9.3 13.4 3.3 117.6 10.6 8.2 16.9 30.7 2.1 13.1 12.3 30.2 183.6 8.4 5.5 8.2 64.8 9.7 13.5 5.5 17.0 12.4 12.9 8.0 8.4 2.6 8.5 13.1 15.6 18.6 1.7 4.1 15.9 33.2 9.7 14.7 15.3 7.8 9.2 LYZ ENSG00000090382 Lysozyme P61626 12 69348381-69354234 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase" "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 10588.1;salivary gland: 21115.5;stomach 1: 8941.1" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 3106.1;Kupffer cells: 2841.2;Langerhans cells: 4859.1;Macrophages: 4870.7;monocytes: 7063.0;Pancreatic endocrine cells: 3152.5" "Cancer enhanced" "Detected in all" "stomach cancer: 976.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 25266.2;myeloid DC: 14438.7" "Group enriched" "Detected in all" 20 "dendritic cells: 14438.7;monocytes: 25266.2" "Cell line enriched" "Detected in many" 13 "OE19: 12130.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000055, HPA048284, HPA066182" Enhanced Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" NA NA 1500000000 1500000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus, Actin filaments" Nucleoplasm "CAB000055: AB_2341230, HPA048284: AB_2680339, HPA066182: AB_2732741" "unprognostic (8.52e-2)" "unprognostic (6.12e-3)" "unprognostic (2.83e-1)" "unprognostic (7.29e-2)" "unprognostic (7.91e-2)" "prognostic favorable (7.45e-4)" "unprognostic (1.21e-1)" "unprognostic (7.40e-2)" "unprognostic (1.41e-1)" "unprognostic (2.08e-2)" "unprognostic (1.44e-1)" "unprognostic (3.13e-1)" "unprognostic (2.50e-1)" "unprognostic (2.37e-1)" "unprognostic (3.65e-2)" "unprognostic (5.78e-2)" "unprognostic (3.62e-2)" 95.8 27.8 3.5 802.1 4.0 10588.1 128.2 3.7 18.5 156.2 11.4 309.0 3605.0 65.7 4.2 106.3 33.9 1054.6 34.8 2.6 4.3 32.4 138.0 1355.2 739.7 8.0 7.3 20.4 63.1 13.8 7.2 91.3 12.2 40.2 273.8 4.4 21115.5 21.8 34.0 58.7 1322.2 123.9 5.4 621.0 8941.1 21.8 10.9 321.8 27.8 36.4 652.8 428.5 16.2 11.7 0.6 0.1 0.0 0.2 0.0 0.0 4.8 0.0 0.0 0.0 0.3 9.5 6.5 4.2 1.5 0.0 3.6 1.2 0.0 0.0 0.2 1.2 0.1 62.4 1.0 960.4 0.0 110.6 50.5 0.0 0.1 0.0 0.0 0.2 0.0 0.3 7.7 0.3 0.0 0.2 2.6 109.5 2.3 12130.8 0.2 1.6 1.4 16.7 0.3 0.5 0.8 3.6 0.5 0.1 0.5 0.7 0.0 489.0 0.6 0.0 2.6 2.3 0.9 2.6 1.1 1.2 0.1 518.5 0.0 443.4 25266.2 298.2 32.6 4798.4 52.3 100.5 20.1 22.7 14438.7 20.8 20.0 17.8 1007.7 108.1 880.1 301.2 31.1 25392.1 3.5 4.0 3.7 18.5 2.6 4.3 8.0 7.3 12.2 5.4 10.9 11.7 24.0 86.6 285.8 0.0 80.8 57.2 1.7 1.2 1.2 0.3 1205.7 32.3 0.2 734.9 51.1 27.6 0.0 5.6 39.6 32.1 0.0 55.1 1.9 2.6 1.9 25.1 12.5 264.6 0.2 547.3 9.4 26.8 3106.1 2.9 123.6 0.5 29.6 25.4 887.1 0.0 0.2 112.4 0.0 2841.2 4859.1 17.4 4.1 4870.7 53.4 0.0 7063.0 0.1 176.1 0.0 0.3 3152.5 600.5 2.2 9.0 2.7 41.8 6.6 33.8 1.0 39.5 7.4 9.9 0.7 3.9 1.5 38.2 8.5 50.6 0.3 111.4 38.3 MACF1 "ABP620, ACF7, FLJ45612, FLJ46776, KIAA0465, KIAA1251, MACF" ENSG00000127603 "Microtubule actin crosslinking factor 1" Q9UPN3 1 39081316-39487177 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" Actin-binding "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 1079.0;Cone photoreceptor cells: 779.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013713, HPA068064, HPA068103" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments" NA NA 25000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cell Junctions, Actin filaments" "HPA013713: AB_10600821, HPA068064: AB_2685946, HPA068103: AB_2685953" "unprognostic (2.71e-1)" "unprognostic (3.14e-2)" "unprognostic (5.18e-2)" "unprognostic (1.02e-2)" "unprognostic (9.00e-2)" "unprognostic (6.19e-3)" "unprognostic (1.32e-1)" "unprognostic (7.40e-3)" "unprognostic (5.45e-2)" "unprognostic (1.23e-1)" "unprognostic (1.34e-1)" "unprognostic (3.98e-1)" "prognostic favorable (2.77e-5)" "unprognostic (1.07e-1)" "unprognostic (1.81e-1)" "unprognostic (8.57e-2)" "unprognostic (4.22e-2)" 69.1 62.5 172.0 27.7 197.5 36.2 54.6 174.6 181.6 65.9 119.1 148.6 18.6 130.3 48.7 46.4 92.0 46.4 127.0 159.7 166.1 85.7 63.8 183.6 35.9 190.2 179.0 92.6 51.2 96.9 69.3 34.6 182.9 68.2 25.1 121.2 57.7 41.6 73.0 121.0 62.6 54.2 155.6 84.9 71.3 50.2 193.2 39.3 73.3 55.2 22.8 80.3 62.7 185.3 48.1 54.9 66.7 29.3 53.8 47.3 29.8 62.2 79.4 38.0 33.7 34.3 56.5 24.4 64.6 84.0 62.1 30.6 12.5 45.7 51.2 43.5 33.1 34.0 43.4 56.5 66.0 30.8 15.9 37.0 46.5 105.1 54.3 83.5 104.7 52.0 63.2 25.7 137.0 16.0 23.3 52.7 95.8 20.0 31.7 38.5 89.6 4.5 206.0 50.8 38.2 38.6 24.9 17.2 62.5 76.3 7.5 37.9 115.1 61.6 48.5 28.8 101.9 19.4 19.7 28.8 101.0 32.6 55.2 7.5 1.3 3.8 12.2 2.7 5.9 2.2 5.8 7.8 1.8 3.8 4.7 6.1 1.3 6.5 2.9 2.5 3.0 2.0 172.0 197.5 174.6 181.6 159.7 166.1 190.2 179.0 182.9 155.6 193.2 185.3 135.3 150.6 128.2 1079.0 68.7 154.4 74.9 43.0 60.3 387.7 52.5 50.9 246.1 61.5 70.7 80.9 779.8 52.6 120.5 35.4 0.0 113.3 9.6 140.6 124.4 164.3 36.1 57.6 320.6 114.6 62.1 108.2 65.2 180.1 77.7 194.3 132.1 47.9 52.1 117.8 367.5 27.2 22.4 59.7 46.3 11.8 43.8 74.8 71.2 342.9 59.0 107.8 158.6 494.6 410.7 193.5 17.7 112.5 81.0 89.7 22.5 20.6 71.3 398.5 105.2 95.5 136.7 62.6 33.7 43.5 191.5 69.9 131.2 76.5 19.7 78.8 MAP3K10 "MEKK10, MLK2, MST" ENSG00000130758 "Mitogen-activated protein kinase kinase kinase 10" Q02779 19 40191426-40215575 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 46.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 18.9;Horizontal cells: 23.5" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 8 "amygdala: 22.8;basal ganglia: 17.5;cerebral cortex: 46.2;hippocampal formation: 37.7;white matter: 11.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007039 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Actin filaments, Cytosol" "HPA007039: AB_1079357" "unprognostic (2.09e-1)" "unprognostic (3.77e-2)" "unprognostic (1.42e-3)" "unprognostic (2.03e-2)" "unprognostic (2.04e-1)" "prognostic favorable (8.69e-4)" "unprognostic (4.50e-3)" "unprognostic (1.80e-1)" "unprognostic (3.94e-2)" "unprognostic (6.13e-2)" "unprognostic (1.34e-3)" "unprognostic (4.62e-3)" "unprognostic (6.88e-2)" "unprognostic (1.53e-2)" "unprognostic (1.51e-2)" "unprognostic (4.77e-3)" "prognostic favorable (2.13e-4)" 6.9 8.3 22.8 2.3 17.5 1.9 6.5 0.0 46.2 7.7 0.0 8.6 2.0 7.9 0.3 5.3 6.6 1.8 10.7 37.7 0.1 7.4 5.2 6.7 2.3 3.2 0.6 7.3 6.9 3.3 14.3 1.6 0.0 8.1 0.6 1.4 5.9 2.0 16.8 7.1 6.3 1.8 0.0 8.1 7.1 11.1 2.4 1.8 6.9 4.3 0.9 7.2 6.6 11.6 6.3 7.2 2.2 5.2 2.0 1.2 6.2 4.3 2.0 1.9 1.9 1.7 1.7 5.7 4.4 1.4 4.6 1.9 0.8 2.2 0.2 10.9 6.8 1.4 3.3 1.7 3.8 1.2 3.4 1.1 5.0 2.0 1.4 2.0 1.7 7.6 5.5 9.1 0.5 3.7 4.5 2.2 2.6 2.0 4.7 5.8 2.3 3.4 1.7 3.8 7.4 10.7 4.9 1.7 10.0 1.3 2.4 2.2 2.9 4.9 4.8 7.3 8.3 12.7 7.7 2.6 5.7 2.3 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.8 17.5 0.0 46.2 37.7 0.1 3.2 0.6 0.0 0.0 2.4 11.6 5.6 0.0 0.0 6.5 4.2 1.5 1.8 1.1 1.2 14.9 2.9 2.4 2.8 5.7 0.5 7.3 8.4 0.9 3.3 2.4 0.0 2.5 2.8 2.4 3.6 3.6 4.2 5.3 18.9 4.3 0.8 2.6 5.6 3.8 0.0 10.3 3.9 3.2 2.5 23.5 15.9 1.7 0.0 1.6 2.9 7.6 3.1 2.7 1.8 9.4 2.5 5.7 4.1 9.0 12.4 3.7 2.9 4.9 1.5 2.5 1.7 3.1 0.6 7.7 6.6 4.5 4.0 4.1 1.8 1.8 2.7 1.4 4.4 3.2 2.4 2.0 MARCKSL1 "F52, MacMARCKS, MLP, MLP1" ENSG00000175130 "MARCKS like 1" P49006 1 32333839-32336233 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 712.7" "Cell type enhanced" "Detected in many" "monocytes: 941.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 8 "eosinophil: 252.7" "Lineage enriched" "Detected in all" 8 "granulocytes: 252.7" "Cell line enhanced" "Detected in many" "AF22: 1016.3;NTERA-2: 984.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020787, HPA030528" Enhanced Supported "Nucleoplasm,Actin filaments,Cytosol" NA Yes 170000 "Cluster 52: Eosinophils - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 5: NTERA-2 - Transcription" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "Nucleoplasm, Actin filaments" "CAB020787: , HPA030528: AB_2673514" "unprognostic (8.08e-2)" "unprognostic (1.28e-1)" "unprognostic (1.11e-1)" "unprognostic (1.04e-2)" "unprognostic (1.38e-1)" "unprognostic (3.16e-3)" "prognostic unfavorable (1.78e-6)" "unprognostic (3.65e-1)" "unprognostic (1.72e-1)" "unprognostic (8.41e-3)" "unprognostic (2.91e-1)" "unprognostic (1.76e-2)" "prognostic unfavorable (1.20e-4)" "unprognostic (1.50e-1)" "unprognostic (8.16e-3)" "unprognostic (1.08e-1)" "unprognostic (3.22e-2)" 63.4 59.9 363.5 82.1 510.3 50.1 102.9 540.1 438.2 81.2 206.4 108.1 61.8 93.4 155.8 15.1 72.2 97.2 55.0 343.0 408.0 51.1 38.7 40.0 176.0 631.5 504.7 358.0 23.7 6.5 22.9 42.9 534.9 84.7 116.5 37.9 75.9 49.9 8.7 28.3 56.1 42.7 467.9 63.1 132.8 139.2 466.4 166.0 110.3 11.0 199.5 77.8 27.1 712.7 82.9 73.3 1016.3 418.6 22.5 8.3 181.0 34.0 21.2 99.9 66.0 176.0 59.9 185.7 124.4 23.2 0.3 43.0 333.1 3.8 73.3 4.5 246.5 10.0 27.0 392.4 68.7 48.8 0.9 114.8 13.7 75.0 2.1 154.2 295.0 312.6 291.5 2.2 135.7 197.5 613.5 205.9 984.3 267.4 168.1 754.8 109.4 87.7 152.1 163.1 629.0 597.8 178.8 194.2 587.8 411.9 135.4 85.8 87.8 41.8 241.3 3.9 66.1 27.8 2.3 489.8 4.7 73.6 225.7 3.1 4.0 252.7 3.8 23.1 1.4 20.0 7.4 4.9 6.6 27.7 15.3 6.4 18.2 1.1 30.3 9.0 4.8 4.9 363.5 510.3 540.1 438.2 343.0 408.0 631.5 504.7 534.9 467.9 466.4 712.7 242.5 0.0 1.3 27.1 191.1 93.7 114.7 43.5 40.5 27.7 465.7 385.8 8.5 178.7 68.8 60.7 6.2 16.1 110.1 194.1 82.2 389.7 37.4 68.7 190.3 326.9 746.2 74.4 4.2 307.2 116.4 124.3 246.2 115.2 22.3 378.6 462.3 5.3 21.2 10.1 21.9 514.2 236.0 61.0 365.3 66.7 613.3 82.0 300.6 9.4 941.4 464.3 46.4 93.0 428.3 751.6 292.8 641.3 39.5 418.8 30.2 9.8 15.6 14.8 131.5 40.3 210.0 14.8 102.7 22.5 83.1 13.4 89.8 172.0 447.1 586.9 METTL15 "FLJ33979, METT5D1" ENSG00000169519 "Methyltransferase like 15" A6NJ78 11 28108248-28527041 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 130.2;Oligodendrocyte precursor cells: 132.7;Oligodendrocytes: 146.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039885 Approved "Golgi apparatus,Plasma membrane,Actin filaments" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Golgi apparatus, Plasma membrane" "Actin filaments" "HPA039885: AB_2676725" "unprognostic (2.57e-1)" "unprognostic (2.64e-1)" "unprognostic (1.00e-2)" "unprognostic (3.21e-2)" "unprognostic (2.66e-2)" "unprognostic (1.83e-1)" "unprognostic (4.17e-2)" "unprognostic (1.95e-1)" "unprognostic (2.94e-2)" "unprognostic (7.93e-2)" "unprognostic (6.31e-3)" "unprognostic (2.28e-1)" "prognostic favorable (7.95e-5)" "unprognostic (7.77e-2)" "unprognostic (1.38e-1)" "unprognostic (6.58e-2)" "unprognostic (6.84e-3)" 4.3 8.1 4.8 4.1 4.5 2.3 6.2 5.5 5.4 6.1 6.1 7.0 5.1 5.0 5.7 4.6 5.7 4.5 7.7 4.9 5.4 7.7 9.3 4.3 5.3 4.9 4.8 5.9 4.4 7.0 4.2 5.1 5.2 6.3 6.9 7.0 4.5 5.6 8.7 5.1 5.1 4.5 4.5 4.3 5.4 3.3 5.2 5.2 7.6 11.2 5.3 4.4 3.3 6.2 8.8 9.2 9.3 7.1 11.3 18.0 6.5 10.6 8.1 10.6 10.9 6.3 5.9 20.2 6.2 8.8 6.7 7.3 12.3 10.9 20.2 12.5 10.8 6.4 6.5 7.3 12.6 12.1 5.6 10.2 16.0 5.9 15.1 11.5 10.3 6.7 13.7 8.9 12.6 6.0 8.4 7.4 7.2 9.2 6.8 4.5 20.2 7.4 15.8 5.0 8.2 6.7 8.8 7.8 12.7 8.9 15.4 7.4 7.8 9.6 7.4 12.3 9.4 6.0 7.6 11.7 13.5 12.0 10.6 2.1 1.4 3.7 2.2 1.0 2.7 3.6 2.6 2.9 1.7 1.8 2.8 3.6 0.6 4.4 1.2 1.8 3.1 1.5 4.8 4.5 5.5 5.4 4.9 5.4 4.9 4.8 5.2 4.5 5.2 6.2 16.5 12.8 24.3 130.2 21.3 44.0 38.1 37.1 23.9 13.6 21.6 15.0 14.3 14.3 20.3 11.0 18.8 11.3 28.7 18.2 11.7 10.6 34.5 19.6 24.7 15.7 9.6 17.0 96.8 11.8 14.1 23.5 16.3 28.2 5.1 18.1 12.8 15.0 10.4 13.5 93.9 17.6 10.2 14.2 50.7 12.6 10.8 17.9 14.2 105.9 6.1 8.7 19.6 132.7 146.1 9.9 13.3 8.2 21.0 57.2 13.0 14.9 18.9 16.1 6.6 60.7 23.2 17.9 10.0 17.4 35.7 8.5 35.5 21.3 16.2 53.1 MYH10 NMMHCB ENSG00000133026 "Myosin heavy chain 10" P35580 17 8474207-8630761 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell shape" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 171.9;Excitatory neurons: 221.3;Inhibitory neurons: 151.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 216.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017180, HPA047541, HPA057198" Enhanced Supported "Actin filaments,Mitochondria,Cytosol" NA NA 28000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" "Actin filaments" "Mitochondria, Cytosol" "CAB017180: , HPA047541: AB_2680081, HPA057198: AB_2683364" "unprognostic (4.67e-2)" "unprognostic (9.64e-3)" "unprognostic (1.13e-1)" "unprognostic (2.52e-3)" "unprognostic (2.40e-1)" "unprognostic (2.33e-2)" "unprognostic (2.75e-1)" "unprognostic (6.45e-2)" "unprognostic (4.77e-2)" "unprognostic (1.11e-1)" "unprognostic (1.39e-3)" "unprognostic (1.69e-2)" "prognostic favorable (1.38e-4)" "unprognostic (2.02e-2)" "unprognostic (2.73e-1)" "unprognostic (5.58e-2)" "prognostic unfavorable (6.42e-4)" 27.3 16.9 12.6 6.1 18.9 13.4 14.7 7.0 29.0 19.6 12.6 12.2 2.3 27.8 16.8 6.6 25.2 26.1 38.9 17.9 8.0 32.5 18.9 66.9 6.5 9.6 7.3 25.9 9.8 13.8 17.7 53.4 9.6 17.7 3.8 22.5 6.6 26.6 4.9 7.9 5.8 22.1 0.5 4.6 9.5 7.4 11.0 5.8 13.6 8.2 4.0 10.5 10.3 13.2 54.1 35.1 216.3 72.7 27.7 33.1 97.1 44.2 39.7 52.2 55.8 94.5 8.0 0.5 28.6 43.9 28.4 5.2 108.7 53.0 58.1 1.2 88.3 62.3 21.7 83.0 64.7 5.4 4.2 47.3 18.9 67.7 26.1 32.1 85.3 70.9 88.1 0.2 32.9 21.6 67.2 1.7 102.1 3.6 7.7 105.9 64.2 0.2 59.1 22.3 17.7 96.8 69.2 3.4 68.1 165.0 18.3 3.6 2.8 48.7 35.6 0.3 38.5 8.3 10.8 13.4 0.3 5.0 111.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 12.6 18.9 7.0 29.0 17.9 8.0 9.6 7.3 9.6 0.5 11.0 13.2 43.0 22.4 14.1 43.1 1.1 4.7 9.5 11.2 9.6 37.1 18.7 16.4 33.5 12.8 11.5 101.2 50.1 171.9 1.0 0.8 17.6 13.7 49.1 28.1 37.6 30.6 2.4 43.5 221.3 1.7 88.6 58.0 3.1 28.5 1.3 41.6 55.6 15.3 15.8 35.3 151.1 1.9 6.1 2.7 3.7 28.6 3.7 1.3 1.8 15.9 0.7 25.9 2.1 96.5 15.5 1.9 0.7 39.9 0.6 7.6 0.0 14.0 21.7 39.4 0.0 12.4 23.6 15.6 27.8 9.5 4.0 76.5 2.0 28.0 2.2 4.4 MYO3A DFNB30 ENSG00000095777 "Myosin IIIA" Q8NEV4 10 25934229-26212532 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hearing, Sensory transduction, Vision" "Actin-binding, Kinase, Motor protein, Myosin, Serine/threonine-protein kinase, Transferase" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "retina: 15.5;testis: 5.2" "Cell type enhanced" "Detected in some" "Early spermatids: 156.6;Late spermatids: 58.2;Muller glia cells: 74.8;Spermatocytes: 31.7" "Cancer enhanced" "Detected in many" "cervical cancer: 1.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.3;CAPAN-2: 1.2;HEK 293: 1.5;SCLC-21H: 1.4;U-2 OS: 2.4;U-698: 6.3" "Not detected" "Not detected" "HPA051893, HPA075413" Enhanced Supported "Plasma membrane,Actin filaments,Cytoplasmic bodies" No No "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" "Actin filaments, Cytoplasmic bodies" "Plasma membrane" "HPA051893: , HPA075413: " "unprognostic (5.00e-3)" "unprognostic (3.36e-2)" "unprognostic (1.53e-1)" "unprognostic (3.20e-3)" "unprognostic (2.96e-1)" "unprognostic (4.37e-2)" "unprognostic (5.29e-2)" "unprognostic (2.74e-1)" "unprognostic (4.31e-2)" "unprognostic (1.03e-1)" "unprognostic (5.66e-3)" "unprognostic (7.96e-3)" "unprognostic (6.34e-2)" "unprognostic (1.46e-2)" "unprognostic (6.62e-2)" "unprognostic (9.69e-2)" 0.1 0.1 0.4 0.0 1.8 0.1 0.1 0.0 0.8 0.1 0.2 0.1 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.1 0.6 0.3 0.0 0.1 0.0 0.6 0.5 0.0 0.7 0.0 0.5 0.0 0.5 0.1 0.3 15.5 0.0 0.1 0.0 0.7 0.1 0.0 0.2 0.0 0.2 5.2 0.3 0.2 0.2 0.1 0.2 0.0 0.3 0.3 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.9 0.8 0.0 0.0 0.7 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.8 0.0 0.8 0.1 0.6 0.6 0.5 0.5 0.2 0.3 0.3 0.2 0.0 0.5 2.0 0.1 1.8 0.3 0.0 0.0 0.9 0.6 0.3 0.6 0.0 2.5 0.0 0.0 0.0 0.0 0.2 1.9 0.8 156.6 0.6 0.1 0.3 1.8 0.0 2.2 0.0 0.4 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 5.9 0.4 0.0 0.0 0.0 58.2 1.2 0.1 0.0 1.9 0.0 74.8 0.0 1.0 0.4 0.2 0.0 1.2 0.0 0.3 0.0 1.0 0.0 3.9 0.0 0.0 2.4 31.7 14.2 2.4 1.0 0.0 0.0 0.0 0.4 0.3 NDC1 "FLJ10407, NET3, TMEM48" ENSG00000058804 "NDC1 transmembrane nucleoporin" Q9BTX1 1 53765478-53838463 "Metabolic proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069751, HPA070882" Approved Supported "Nuclear membrane,Plasma membrane,Actin filaments" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear membrane" "Plasma membrane, Actin filaments" "HPA069751: AB_2686189, HPA070882: AB_2686320" "unprognostic (2.51e-1)" "unprognostic (1.93e-1)" "prognostic favorable (4.48e-5)" "unprognostic (6.96e-3)" "unprognostic (1.31e-1)" "unprognostic (1.36e-3)" "prognostic unfavorable (7.52e-7)" "unprognostic (3.46e-3)" "unprognostic (1.53e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (3.58e-4)" "unprognostic (9.27e-2)" "unprognostic (6.22e-3)" "unprognostic (3.00e-3)" "unprognostic (4.38e-2)" "unprognostic (9.24e-2)" "unprognostic (6.07e-2)" 5.4 5.2 3.4 9.5 3.5 8.4 11.1 3.6 4.1 5.7 3.6 11.9 8.9 6.5 7.4 7.7 7.5 4.6 4.5 3.6 3.4 6.9 7.8 4.7 15.7 3.2 3.3 5.9 4.7 9.5 1.7 8.0 3.3 4.8 14.2 6.0 4.2 5.2 4.3 7.3 8.2 7.1 3.5 5.6 6.4 7.5 3.5 14.2 6.8 5.2 18.4 7.1 4.2 3.9 61.6 31.2 42.8 43.7 15.5 15.5 49.3 40.9 31.0 63.8 51.1 47.5 40.4 119.0 26.2 18.6 51.2 72.0 73.2 43.3 89.8 29.8 50.9 58.5 42.9 40.5 14.3 95.3 31.9 9.4 17.0 62.9 37.5 18.6 39.1 44.2 67.7 16.9 35.6 22.2 47.2 38.2 101.0 52.2 49.9 52.0 68.4 66.0 29.8 41.7 25.4 32.2 36.5 71.5 35.9 45.3 55.3 50.2 22.7 32.9 32.6 45.5 74.9 17.9 48.8 84.7 27.3 71.6 42.2 0.0 2.3 1.5 3.0 5.0 4.7 3.6 2.8 2.7 2.6 2.8 5.3 4.1 0.1 3.1 3.3 2.3 3.4 2.4 3.4 3.5 3.6 4.1 3.6 3.4 3.2 3.3 3.3 3.5 3.5 3.9 4.4 6.4 6.3 12.4 8.7 10.1 6.4 9.0 12.0 4.5 10.1 6.3 8.1 4.3 5.4 5.5 2.1 11.5 5.9 7.9 0.0 8.5 2.3 5.0 5.6 6.1 0.0 19.4 13.8 9.1 20.2 6.3 8.6 4.6 7.6 21.5 5.3 7.1 11.8 3.3 11.0 10.3 16.2 8.2 8.9 2.1 2.8 7.1 7.2 13.1 4.7 3.3 3.1 11.6 19.4 7.0 5.8 3.4 20.1 8.9 2.9 4.5 5.5 2.9 6.6 6.3 15.7 11.8 14.3 18.2 8.5 6.8 6.7 4.3 18.2 6.5 NEGR1 "IGLON4, KILON, MGC46680, Ntra" ENSG00000172260 "Neuronal growth regulator 1" Q7Z3B1 1 71395943-72282539 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 29.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 1968.8;Inhibitory neurons: 1254.4;Oligodendrocyte precursor cells: 726.3;Oligodendrocytes: 442.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 26.7;TIME: 28.5;U-2 OS: 22.9;U-251 MG: 24.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011894 Uncertain Approved "Vesicles,Actin filaments,Cytosol" NA NA 380000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Actin filaments, Cytosol" "HPA011894: AB_1854363" "unprognostic (2.60e-1)" "unprognostic (1.89e-2)" "unprognostic (1.23e-1)" "unprognostic (1.44e-1)" "unprognostic (7.99e-2)" "unprognostic (2.48e-1)" "unprognostic (3.72e-1)" "unprognostic (6.94e-2)" "unprognostic (8.15e-2)" "unprognostic (8.73e-2)" "unprognostic (3.38e-2)" "unprognostic (1.36e-1)" "unprognostic (3.31e-5)" "unprognostic (5.89e-3)" "unprognostic (1.31e-1)" "unprognostic (1.43e-3)" "unprognostic (2.11e-4)" 16.5 5.8 12.8 3.6 15.9 1.2 5.9 4.4 15.7 7.1 0.0 17.5 2.7 5.2 4.1 10.5 7.2 10.7 11.2 15.1 9.1 6.8 0.3 5.5 1.6 1.9 5.6 6.0 4.5 0.7 3.9 2.9 2.7 7.3 7.8 29.8 2.4 5.4 3.3 5.8 5.1 6.4 3.7 0.6 7.4 3.2 12.4 5.6 3.5 5.1 0.8 13.3 6.6 6.5 0.4 0.1 0.8 0.2 26.7 21.0 0.2 19.4 7.2 10.4 12.7 0.1 0.2 0.3 0.1 21.5 0.2 0.6 0.0 0.0 22.4 0.2 0.1 0.1 3.4 0.1 2.2 0.2 0.4 10.2 0.1 8.9 1.5 15.4 12.5 0.3 0.1 0.8 19.5 0.1 0.2 0.2 3.2 0.3 11.0 13.7 20.4 0.3 1.7 0.3 1.5 1.7 6.8 0.1 0.0 0.4 0.1 0.3 28.5 2.3 22.9 0.9 24.5 0.4 0.2 0.1 5.2 13.0 8.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 12.8 15.9 4.4 15.7 15.1 9.1 1.9 5.6 2.7 3.7 12.4 6.5 6.0 0.0 0.5 170.7 0.0 5.0 0.6 0.1 0.0 51.4 0.2 0.5 4.2 1.5 2.5 0.0 27.1 0.0 4.4 0.1 0.0 2.4 6.2 0.1 1.3 2.6 0.0 0.8 1968.8 0.0 0.0 88.7 0.5 0.1 0.0 0.2 0.0 0.0 0.2 1.7 1254.4 0.6 0.0 0.0 16.7 12.5 210.3 2.4 8.8 58.1 3.1 12.2 0.0 726.3 442.7 0.5 0.0 44.8 0.5 1.3 0.0 1.5 7.1 58.7 32.9 8.3 8.5 0.7 2.5 0.3 3.4 0.0 1.1 0.2 0.1 0.7 NOTCH3 "CADASIL, CASIL" ENSG00000074181 "Notch receptor 3" Q9UM47 19 15159038-15200995 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Sertoli cells: 414.2;Skeletal myocytes: 131.6;Smooth muscle cells: 317.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 66.3;MCF7: 66.9;RT4: 41.2;U-87 MG: 45.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005393, HPA044392" Approved Supported "Nucleoplasm,Actin filaments,Cytosol" NA NA 46000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "Actin filaments" "CAB005393: AB_2151246, HPA044392: AB_2678926" "unprognostic (4.97e-2)" "unprognostic (3.89e-2)" "unprognostic (7.06e-3)" "prognostic unfavorable (5.92e-4)" "unprognostic (9.20e-2)" "unprognostic (1.73e-2)" "unprognostic (2.72e-1)" "unprognostic (9.04e-2)" "unprognostic (3.90e-3)" "unprognostic (1.23e-1)" "unprognostic (1.19e-1)" "unprognostic (3.13e-1)" "prognostic unfavorable (2.53e-7)" "unprognostic (3.35e-2)" "unprognostic (8.34e-3)" "unprognostic (4.40e-2)" "unprognostic (2.00e-3)" 85.7 5.3 14.8 10.4 12.4 0.2 50.5 11.0 21.3 49.4 7.1 14.8 5.5 39.9 16.9 74.3 35.8 23.5 43.6 9.5 11.3 26.0 3.2 38.3 9.2 12.0 15.2 18.9 10.7 12.6 10.3 59.8 14.3 22.0 4.2 0.5 24.4 16.5 29.7 82.1 14.3 16.9 8.2 15.0 11.6 3.8 15.8 34.1 32.3 25.1 10.4 26.3 55.1 10.0 13.0 8.1 66.3 30.3 9.2 7.3 29.8 10.2 0.4 0.4 0.3 15.6 13.4 0.4 7.7 18.9 0.1 15.1 12.1 0.2 0.6 0.1 3.1 0.4 12.4 3.5 4.5 0.0 1.2 8.4 7.3 15.5 1.6 0.6 0.8 4.6 0.5 0.6 1.2 66.9 15.9 0.1 38.8 11.2 0.0 0.1 3.7 0.3 0.0 41.2 1.9 21.4 0.1 37.8 0.0 19.6 40.3 0.1 0.0 1.9 21.0 0.3 0.1 0.1 0.7 0.0 45.7 0.4 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 14.8 12.4 11.0 21.3 9.5 11.3 12.0 15.2 14.3 8.2 15.8 10.0 39.6 9.6 1.5 5.9 0.4 24.1 7.8 17.8 4.6 0.4 41.5 30.7 60.7 0.0 28.5 16.5 0.0 20.2 1.0 0.0 5.9 14.8 0.5 4.8 13.5 32.0 0.0 0.0 0.6 0.0 3.9 24.2 2.0 11.8 0.0 5.9 4.2 0.0 2.8 0.0 0.3 0.3 6.1 10.4 12.3 0.1 9.0 4.1 17.8 13.1 0.7 0.8 0.0 0.0 0.2 0.9 0.1 11.7 0.0 13.0 0.1 0.0 4.2 0.8 414.2 131.6 317.0 0.9 1.2 72.1 72.2 31.5 2.0 1.2 0.2 36.0 NPM3 ENSG00000107833 "Nucleophosmin/nucleoplasmin 3" O75607 10 101781325-101783413 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036295, HPA036296" Approved Approved "Nucleoli,Actin filaments,Cytosol" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" "Nucleoli, Actin filaments, Cytosol" "HPA036295: AB_10671244, HPA036296: AB_10672083" "unprognostic (3.41e-2)" "unprognostic (3.70e-2)" "unprognostic (4.33e-2)" "unprognostic (1.75e-1)" "unprognostic (8.06e-2)" "prognostic unfavorable (1.42e-4)" "unprognostic (1.00e-2)" "unprognostic (1.98e-1)" "unprognostic (5.17e-2)" "unprognostic (1.75e-1)" "unprognostic (2.45e-2)" "unprognostic (1.35e-2)" "unprognostic (2.86e-2)" "unprognostic (3.55e-2)" "unprognostic (1.81e-1)" "unprognostic (5.69e-2)" "unprognostic (9.58e-2)" 12.7 19.5 9.9 18.5 10.2 27.2 19.0 7.8 10.4 19.6 9.6 15.5 8.3 17.2 10.1 26.6 15.3 9.8 8.4 9.6 11.6 16.4 12.3 10.2 23.3 8.4 8.5 20.6 30.3 16.4 12.4 16.3 8.6 13.4 19.3 1.1 15.1 8.2 13.3 16.7 10.7 19.9 8.5 14.8 13.1 17.1 11.6 20.3 11.1 10.1 25.9 20.9 16.7 9.3 94.8 117.2 34.2 226.2 76.5 80.0 36.1 50.0 75.7 75.8 64.4 126.5 117.1 154.8 91.0 56.0 41.6 99.2 192.6 211.8 59.3 66.1 199.8 124.5 50.5 206.0 86.1 286.6 87.4 69.6 100.8 105.2 417.0 39.0 100.6 187.1 156.9 83.7 63.3 173.8 121.0 371.8 60.7 131.1 89.1 93.3 179.2 158.0 75.0 45.8 70.0 45.1 31.2 72.5 144.7 41.8 94.4 59.0 40.1 30.0 95.8 44.8 94.1 36.0 39.9 179.7 41.9 263.4 31.8 0.0 2.8 0.0 3.6 4.0 6.5 4.0 5.9 6.9 6.4 4.8 9.5 9.8 0.1 8.1 0.8 8.3 2.6 5.1 9.9 10.2 7.8 10.4 9.6 11.6 8.4 8.5 8.6 8.5 11.6 9.3 5.1 3.2 5.0 1.0 15.3 62.7 79.6 121.4 28.5 1.4 55.5 54.4 2.9 28.6 32.0 36.8 0.0 91.4 15.6 16.3 78.2 54.0 8.9 7.3 22.1 21.6 24.2 17.9 2.7 41.2 90.6 29.7 13.7 10.5 16.5 19.6 15.0 19.0 68.6 0.0 2.0 33.1 46.8 21.1 69.9 10.9 28.0 18.0 30.2 1.9 14.7 2.5 18.6 1.5 1.0 34.2 12.7 23.7 19.1 118.5 3.1 61.6 16.4 2.0 6.6 47.9 21.6 46.5 91.3 21.3 49.9 60.7 18.5 29.0 46.9 62.8 NPTX2 ENSG00000106236 "Neuronal pentraxin 2" P47972 7 98617285-98629869 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 135.8;pituitary gland: 210.8" "Cell type enhanced" "Detected in many" "Granulosa cells: 93.5;Peritubular cells: 326.1;Sertoli cells: 151.2;Spermatocytes: 85.2;Spermatogonia: 94.8" "Cancer enhanced" "Detected in all" "renal cancer: 41.7" "Region enhanced" "Detected in all" "cerebral cortex: 135.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "LHCN-M2: 717.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB020801, HPA049799, HPA058320" Enhanced Approved "Golgi apparatus,Actin filaments,Centrosome" "Secreted to blood" NA NA 2490000 360000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus, Actin filaments" Centrosome "CAB020801: , HPA049799: AB_2680889, HPA058320: AB_2732621" "unprognostic (1.18e-1)" "unprognostic (9.61e-2)" "unprognostic (1.56e-2)" "prognostic unfavorable (5.46e-5)" "unprognostic (1.91e-3)" "unprognostic (9.20e-2)" "unprognostic (2.42e-2)" "unprognostic (6.04e-3)" "unprognostic (1.11e-1)" "unprognostic (1.74e-1)" "unprognostic (7.64e-2)" "unprognostic (2.35e-1)" "prognostic unfavorable (5.46e-9)" "unprognostic (1.06e-2)" "unprognostic (1.21e-1)" "unprognostic (5.33e-2)" "unprognostic (3.69e-2)" 7.0 39.2 11.2 1.9 13.6 0.5 3.8 10.1 135.8 9.9 2.5 15.3 0.5 5.7 3.5 3.0 2.8 1.1 9.8 39.2 47.3 1.1 2.6 0.9 0.1 13.8 14.5 3.7 21.4 0.6 210.8 0.1 16.2 7.2 0.8 4.7 3.7 1.6 8.9 8.2 5.4 2.5 6.4 13.0 6.7 34.3 45.6 0.5 3.1 6.7 0.3 5.5 6.9 16.8 0.0 0.0 6.5 0.2 0.0 0.5 0.0 8.8 0.0 0.1 0.0 0.0 0.0 0.0 21.1 2.8 1.5 0.0 0.9 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.2 5.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 717.9 0.0 5.7 0.0 35.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.1 33.8 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.1 0.5 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 11.2 13.6 10.1 135.8 39.2 47.3 13.8 14.5 16.2 6.4 45.6 16.8 8.6 0.0 0.6 2.9 0.3 3.8 0.5 0.0 0.0 19.9 0.2 1.4 3.4 5.7 1.3 0.0 4.2 0.0 1.0 4.5 0.0 5.4 12.0 8.5 1.8 16.9 16.0 0.0 22.1 12.8 0.2 11.1 1.5 10.5 0.0 93.5 3.9 0.7 0.5 0.0 5.3 1.2 0.0 0.0 5.4 24.2 14.0 1.3 12.4 5.6 0.0 1.6 0.0 1.0 1.8 2.9 1.1 326.1 1.0 5.2 0.5 0.1 0.0 2.8 151.2 57.2 27.1 85.2 94.8 0.1 3.0 0.1 0.8 12.7 2.3 1.2 NTN1 NTN1L ENSG00000065320 "Netrin 1" O95631 17 9021510-9244000 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.1;heart muscle: 59.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 137.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 27.5;T-47d: 16.6;U-2 OS: 14.4;U-251 MG: 22.1;WM-115: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056419 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" "Secreted to extracellular matrix" NA NA 110000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "Nucleoplasm, Actin filaments" "HPA056419: AB_2683124" "unprognostic (2.72e-1)" "unprognostic (2.59e-2)" "unprognostic (7.12e-2)" "unprognostic (5.25e-2)" "unprognostic (2.51e-1)" "unprognostic (9.33e-3)" "unprognostic (9.42e-2)" "unprognostic (2.20e-1)" "unprognostic (1.63e-1)" "unprognostic (1.33e-2)" "unprognostic (1.89e-1)" "unprognostic (1.15e-1)" "unprognostic (2.49e-2)" "unprognostic (2.20e-2)" "unprognostic (2.60e-1)" "unprognostic (6.07e-3)" "unprognostic (8.31e-3)" 6.4 0.5 4.5 3.6 6.4 0.1 5.3 10.1 4.9 9.3 2.8 14.7 6.7 9.6 3.5 18.9 10.3 7.3 59.4 3.8 7.0 2.0 6.9 4.3 0.2 12.7 37.1 0.9 2.3 4.3 3.0 0.9 14.4 3.9 3.9 0.4 10.9 2.0 2.1 8.1 10.5 6.0 13.8 0.1 17.5 3.1 10.1 2.9 2.0 2.6 2.1 10.2 5.4 8.8 0.1 0.0 1.3 4.6 4.2 0.1 27.5 0.3 0.4 0.3 0.5 0.1 5.7 0.0 6.2 0.0 9.0 0.1 1.2 0.9 0.0 6.4 10.4 1.4 0.0 0.0 0.1 0.5 0.1 0.1 2.1 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.1 5.6 0.1 0.6 1.8 0.0 0.0 3.4 4.8 0.0 0.0 0.3 0.0 0.0 0.1 4.7 1.1 4.5 16.6 0.3 0.0 6.7 14.4 0.0 22.1 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 6.4 10.1 4.9 3.8 7.0 12.7 37.1 14.4 13.8 10.1 8.8 0.7 0.0 0.0 10.7 0.3 3.3 6.6 21.8 9.6 2.9 4.7 4.4 28.1 0.0 23.9 1.8 0.0 0.3 0.2 0.5 0.0 3.1 9.3 5.8 2.0 3.1 0.0 0.0 4.8 1.7 1.2 9.7 1.1 7.9 0.0 0.0 2.2 12.4 0.1 0.0 7.1 1.4 24.4 0.6 5.9 4.6 0.3 0.1 1.8 9.4 0.6 0.3 0.0 137.2 1.0 1.4 0.1 0.0 0.0 4.0 0.7 0.2 11.1 0.2 0.0 3.9 6.8 1.6 2.0 12.7 2.8 0.5 0.5 0.0 0.6 3.5 PALMD "C1orf11, FLJ20271, PALML" ENSG00000099260 Palmdelphin Q9NP74 1 99646113-99694541 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 130.8" "Cell type enhanced" "Detected in many" "Adipocytes: 537.2;Cardiomyocytes: 157.6;Endothelial cells: 219.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 155.2;LHCN-M2: 49.5;TIME: 220.5;U-87 MG: 92.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017959, HPA030549" Supported Supported "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Actin filaments" "Plasma membrane, Focal adhesion sites" "HPA017959: AB_1854949, HPA030549: AB_2673518" "unprognostic (1.48e-2)" "unprognostic (1.15e-2)" "unprognostic (2.05e-2)" "prognostic favorable (9.42e-4)" "unprognostic (7.67e-2)" "prognostic favorable (5.90e-5)" "unprognostic (1.54e-2)" "unprognostic (2.10e-1)" "unprognostic (3.93e-2)" "unprognostic (1.64e-1)" "unprognostic (8.32e-2)" "unprognostic (6.18e-2)" "unprognostic (5.19e-2)" "unprognostic (1.63e-2)" "unprognostic (1.88e-1)" "unprognostic (2.70e-1)" "unprognostic (8.08e-2)" 130.8 43.0 14.6 7.1 11.7 0.0 77.6 10.5 15.3 27.4 45.8 9.5 3.4 33.0 6.1 38.2 22.8 14.6 91.2 13.7 12.7 11.0 57.1 28.4 3.9 12.0 11.8 18.8 4.9 9.2 10.5 43.2 11.5 18.0 6.5 7.5 71.0 7.9 112.6 48.9 8.6 31.4 11.1 6.3 6.1 11.0 14.1 8.0 7.2 66.2 8.6 14.5 15.9 10.4 0.0 0.3 0.4 0.2 7.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 39.2 2.5 0.6 10.8 0.0 0.5 0.1 0.1 0.1 0.0 18.6 26.4 0.0 0.0 0.1 3.9 2.0 0.0 0.0 4.3 155.2 0.0 22.7 0.0 49.5 0.6 0.0 0.0 0.0 1.6 6.8 0.0 38.2 0.1 0.0 8.0 0.9 0.5 0.0 9.9 0.0 1.0 2.3 0.0 220.5 0.0 0.4 16.8 0.0 0.0 0.0 0.1 92.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 11.7 10.5 15.3 13.7 12.7 12.0 11.8 11.5 11.1 14.1 10.4 537.2 6.4 5.6 0.3 0.5 38.5 11.4 49.6 22.2 2.0 20.0 31.8 157.6 32.9 35.9 3.7 0.0 0.4 1.6 0.1 5.9 8.1 74.9 78.7 71.9 219.4 1.8 2.7 1.4 0.2 0.3 19.2 2.0 17.7 1.3 0.0 96.0 57.3 0.6 3.3 1.8 0.0 14.2 2.2 5.5 12.2 9.3 1.7 24.9 73.1 0.0 55.0 0.0 0.5 0.2 4.1 0.0 24.0 0.0 5.9 0.0 0.4 111.5 3.3 0.0 91.3 12.7 0.5 0.6 27.5 46.5 0.3 1.4 110.1 0.1 3.3 PARD6A "PAR-6, PAR-6A, PAR6alpha, TAX40, TIP-40" ENSG00000102981 "Par-6 family cell polarity regulator alpha" Q9NPB6 16 67660946-67662774 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.5;testis: 42.9" "Cell type enriched" "Detected in many" 4 "Late spermatids: 266.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "REH: 27.9;RPMI-8226: 24.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009733, HPA041551" Approved Supported "Cell Junctions,Actin filaments,Cytosol" No No "Cluster 24: B-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" "Cell Junctions, Actin filaments" Cytosol "CAB009733: AB_2159676, HPA041551: AB_2677545" "prognostic favorable (5.40e-4)" "unprognostic (6.18e-2)" "unprognostic (1.77e-1)" "unprognostic (1.33e-2)" "unprognostic (7.63e-2)" "unprognostic (4.08e-3)" "unprognostic (1.23e-2)" "unprognostic (1.27e-1)" "unprognostic (6.59e-2)" "unprognostic (2.09e-1)" "unprognostic (1.98e-3)" "unprognostic (9.13e-2)" "prognostic favorable (3.08e-7)" "unprognostic (9.22e-3)" "unprognostic (6.69e-2)" "unprognostic (1.25e-1)" "unprognostic (1.39e-2)" 3.2 8.0 25.1 2.4 24.8 1.3 2.8 32.4 38.5 2.1 19.3 7.7 1.1 2.6 2.1 2.0 2.7 1.9 4.2 28.1 22.3 8.8 6.5 3.1 3.1 25.3 22.8 3.9 27.9 6.6 30.2 0.7 26.8 3.6 1.0 2.7 2.7 2.7 8.7 1.8 4.1 1.6 21.9 4.8 5.9 42.9 25.8 3.4 2.4 5.3 2.2 3.7 1.7 25.4 8.9 9.4 2.6 23.5 1.7 0.4 4.7 0.2 1.1 3.4 3.2 4.7 3.6 14.8 4.3 0.3 1.2 7.0 5.2 1.1 0.7 6.9 5.0 6.0 4.1 5.5 2.4 2.5 13.5 0.1 0.5 3.2 1.3 2.1 1.7 21.7 0.6 3.4 0.6 8.7 15.6 3.2 3.3 12.0 6.0 27.9 1.7 24.5 8.8 5.1 21.8 11.7 1.4 3.2 3.7 0.7 19.9 0.9 1.4 0.3 0.8 2.1 4.6 3.5 12.1 13.5 2.6 5.3 1.0 2.1 0.9 0.4 4.3 0.6 7.8 10.9 5.9 5.4 1.1 8.3 2.8 2.2 3.4 1.3 0.1 5.1 6.3 2.0 25.1 24.8 32.4 38.5 28.1 22.3 25.3 22.8 26.8 21.9 25.8 25.4 4.4 3.2 5.8 2.0 17.0 0.9 2.2 1.6 1.2 11.1 7.7 6.7 1.7 10.0 2.6 20.2 4.2 5.7 8.2 3.5 33.2 7.2 61.0 4.1 0.5 3.2 34.0 4.0 7.2 15.0 0.4 3.3 6.1 2.7 5.7 5.2 3.9 4.6 4.3 32.0 7.3 3.3 0.0 4.1 5.7 266.5 3.7 4.7 5.4 3.7 2.2 19.1 1.0 2.0 2.2 6.0 2.1 1.5 12.1 2.1 2.9 16.3 3.4 10.1 0.0 8.0 9.7 5.5 3.9 1.4 1.6 2.9 15.0 1.9 4.7 2.4 PARVA "FLJ10793, FLJ12254, MXRA2" ENSG00000197702 "Parvin alpha" Q9NVD7 11 12377563-12535356 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion, Cell shape, Chemotaxis, Cilium biogenesis/degradation" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.0" "Lineage enriched" "Detected in single" 11 "T-cells: 1.0" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 229.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005964 Approved Supported "Actin filaments,Focal adhesion sites,Cytosol" NA NA 7300000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Actin filaments, Focal adhesion sites" Cytosol "HPA005964: AB_1079569" "unprognostic (3.87e-2)" "unprognostic (7.38e-2)" "unprognostic (3.30e-2)" "prognostic favorable (1.76e-4)" "unprognostic (7.37e-3)" "unprognostic (1.38e-2)" "unprognostic (6.78e-2)" "prognostic unfavorable (8.19e-4)" "unprognostic (1.76e-2)" "unprognostic (2.80e-2)" "unprognostic (1.70e-2)" "unprognostic (9.82e-2)" "unprognostic (6.73e-2)" "unprognostic (6.58e-3)" "unprognostic (1.35e-1)" "unprognostic (1.50e-1)" "unprognostic (3.82e-2)" 61.8 17.6 9.3 22.7 9.0 0.1 40.9 7.2 10.1 53.9 16.5 92.4 17.5 71.8 16.7 42.8 38.8 31.9 34.3 9.8 11.6 23.0 16.9 28.8 6.4 11.0 7.3 31.9 36.0 16.9 11.7 35.9 8.4 50.6 38.4 8.9 20.9 68.9 8.1 14.0 26.1 95.5 11.3 11.3 42.5 6.8 8.6 4.6 17.9 11.7 9.1 55.0 28.2 11.0 34.0 33.1 30.2 39.4 147.8 110.6 69.1 126.5 130.1 87.7 81.6 24.7 51.8 0.0 41.1 229.5 9.9 20.7 0.4 66.4 104.0 0.6 14.9 0.1 42.4 18.7 114.7 0.1 0.9 91.3 22.3 37.1 57.4 107.5 110.9 0.0 0.1 0.3 131.8 20.4 0.0 0.2 14.2 20.2 26.4 0.0 75.2 0.2 44.9 32.8 4.8 0.1 97.6 39.1 65.5 66.9 18.4 0.9 138.2 105.1 43.8 57.2 35.4 0.1 0.1 0.2 58.5 0.1 118.3 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 9.0 7.2 10.1 9.8 11.6 11.0 7.3 8.4 11.3 8.6 11.0 37.0 99.3 33.0 47.3 1.1 13.8 25.0 29.3 20.5 4.3 24.4 24.8 45.1 18.6 27.0 27.6 0.0 39.9 0.7 39.6 39.2 56.1 0.9 26.9 62.5 33.3 27.1 0.0 31.4 67.1 92.2 59.1 24.5 35.9 5.1 34.8 39.7 19.1 6.5 0.0 34.9 26.2 18.3 1.8 8.8 2.5 41.0 2.0 46.2 36.5 1.0 25.3 0.0 30.7 1.0 51.7 25.4 51.9 0.2 33.5 23.1 38.1 54.8 2.5 52.6 32.6 60.6 1.1 3.4 20.2 8.9 19.0 2.3 25.1 32.4 25.1 PDLIM1 "CLIM1, CLP-36, CLP36, hCLIM1" ENSG00000107438 "PDZ and LIM domain 1" O00151 10 95237572-95291012 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 675.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 805.9;Basal respiratory cells: 763.8;Paneth cells: 769.2;Proximal enterocytes: 1059.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "eosinophil: 189.7;memory B-cell: 223.8;naive B-cell: 213.0" "Group enriched" "Detected in all" 7 "B-cells: 223.8;granulocytes: 189.7" "Cell line enhanced" "Detected in many" "HaCaT: 766.3;Hep G2: 635.3;HHSteC: 731.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017010, CAB072838, CAB072840" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments" NA NA 93000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Actin filaments" "Plasma membrane, Cell Junctions" "CAB072838: , CAB072840: , HPA017010: AB_1855147" "unprognostic (1.61e-1)" "unprognostic (2.87e-2)" "unprognostic (2.58e-2)" "prognostic favorable (1.14e-5)" "unprognostic (3.18e-2)" "unprognostic (7.54e-2)" "unprognostic (2.07e-1)" "unprognostic (8.99e-2)" "unprognostic (2.26e-1)" "unprognostic (2.82e-3)" "unprognostic (5.77e-2)" "unprognostic (6.56e-2)" "unprognostic (1.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.97e-1)" "unprognostic (4.21e-3)" "unprognostic (1.11e-1)" 301.7 32.4 10.7 91.5 10.8 25.0 236.0 10.2 18.5 133.1 30.2 220.0 179.4 115.0 91.8 182.3 155.3 114.9 393.2 11.7 10.9 82.8 160.3 337.2 104.5 20.4 12.7 35.6 98.3 65.9 29.5 141.1 14.1 116.9 218.5 36.9 166.1 114.7 675.1 136.8 249.0 146.0 14.0 148.3 148.3 13.7 13.8 105.9 194.7 290.0 123.7 276.3 165.3 11.2 274.4 181.8 12.4 0.4 64.1 43.3 277.1 82.6 266.4 218.8 356.5 387.0 429.8 0.3 21.9 233.8 110.4 766.3 91.5 498.1 220.6 0.2 132.0 277.9 50.1 635.3 731.0 0.1 13.2 125.5 257.0 111.9 400.6 233.2 396.8 24.2 60.0 70.3 52.7 51.4 0.8 4.9 24.6 137.7 137.2 234.1 10.0 98.4 114.4 268.9 48.3 18.9 91.2 84.6 0.9 293.8 68.2 125.7 345.1 84.5 19.7 0.7 0.7 31.2 0.1 91.6 92.5 0.2 41.0 0.4 2.4 189.7 11.9 0.8 0.1 223.8 2.3 14.1 31.0 213.0 0.5 8.1 7.5 8.9 1.5 3.2 2.2 44.5 10.7 10.8 10.2 18.5 11.7 10.9 20.4 12.7 14.1 14.0 13.8 11.2 435.0 76.9 123.5 0.0 145.6 366.3 805.9 763.8 244.7 10.1 100.6 131.4 266.2 223.1 250.2 51.5 29.2 538.2 20.5 657.0 15.6 420.1 8.4 218.6 319.3 359.3 101.3 41.6 0.9 172.5 116.7 149.2 100.9 113.0 12.6 47.2 459.7 100.4 50.0 1.7 0.4 488.9 152.5 19.4 105.2 8.0 5.0 88.8 40.9 2.8 8.8 11.6 32.0 0.0 0.0 227.0 769.2 0.7 103.5 256.5 1059.7 109.0 316.4 59.5 315.5 21.0 213.1 4.3 35.7 170.4 197.9 117.0 25.8 1.9 419.2 554.3 PKD2L1 "PCL, PKD2L, PKDL, TRPP3" ENSG00000107593 "Polycystin 2 like 1, transient receptor potential cation channel" Q9P0L9 10 100288149-100330264 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.8;lymphoid tissue: 7.9;retina: 13.3" "Cell type enhanced" "Detected in some" "Early spermatids: 14.6;Hofbauer cells: 13.6;Horizontal cells: 60.6;Kupffer cells: 14.4;Late spermatids: 20.1" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB022621, HPA070002" Uncertain Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Actin filaments, Cytosol" "CAB022621: , HPA070002: " "unprognostic (2.67e-1)" "unprognostic (3.66e-7)" "unprognostic (8.07e-3)" "unprognostic (4.38e-2)" "unprognostic (4.70e-2)" "unprognostic (5.31e-2)" "unprognostic (2.19e-1)" "unprognostic (2.85e-2)" "unprognostic (2.01e-1)" "unprognostic (9.25e-2)" "unprognostic (1.55e-1)" "unprognostic (9.37e-2)" "unprognostic (1.49e-4)" "unprognostic (3.00e-1)" "unprognostic (2.05e-2)" "unprognostic (7.94e-2)" "unprognostic (2.25e-1)" 0.2 0.1 5.4 0.4 5.6 0.9 0.7 4.8 10.8 0.1 4.8 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.4 4.9 0.3 1.6 2.3 1.5 4.9 5.2 0.1 0.1 0.0 0.1 0.5 5.1 0.3 1.2 13.3 0.1 0.0 0.1 0.0 0.6 0.0 5.0 7.9 0.0 2.3 5.0 0.9 0.0 0.0 1.7 0.2 0.0 5.5 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.1 5.4 5.6 4.8 10.8 5.4 4.9 4.9 5.2 5.1 5.0 5.0 5.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 14.6 0.0 0.0 0.1 0.0 0.0 2.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 13.6 60.6 0.4 0.0 0.0 14.4 0.0 20.1 0.3 3.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 PSTK "C10orf89, MGC35392" ENSG00000179988 "Phosphoseryl-tRNA kinase" Q8IV42 10 122954381-122997513 "Enzymes, Predicted intracellular proteins" "Protein biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 31.3;Spermatocytes: 37.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037780, HPA037781" Approved Approved "Nucleoli,Nuclear bodies,Actin filaments" No No "Cluster 24: B-cells - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "Actin filaments" "Nucleoli, Nuclear bodies" "HPA037780: AB_2675662, HPA037781: AB_10670530" "unprognostic (8.95e-3)" "unprognostic (5.51e-3)" "unprognostic (1.37e-1)" "unprognostic (7.39e-4)" "unprognostic (5.21e-2)" "unprognostic (4.08e-3)" "unprognostic (1.60e-2)" "unprognostic (5.92e-4)" "unprognostic (3.55e-2)" "unprognostic (1.16e-1)" "unprognostic (6.22e-3)" "unprognostic (7.10e-3)" "unprognostic (2.39e-1)" "unprognostic (4.50e-2)" "unprognostic (4.92e-2)" "unprognostic (3.02e-2)" "unprognostic (5.55e-4)" 0.9 2.2 1.3 0.6 1.5 6.1 2.9 1.5 2.2 1.9 0.3 1.6 1.9 1.9 3.5 1.5 1.9 0.7 1.7 1.5 1.6 2.0 4.1 1.0 0.9 1.6 1.5 1.3 2.1 1.1 2.6 1.3 2.5 2.0 1.5 0.5 1.9 1.1 3.5 1.6 1.0 1.9 1.3 1.1 1.3 3.2 1.4 1.8 2.4 0.9 1.2 1.3 1.3 2.8 4.1 3.4 1.7 0.8 1.6 3.2 2.1 2.0 3.5 3.0 3.7 4.6 3.4 4.4 3.9 2.5 2.0 2.3 0.7 3.1 3.4 2.4 8.7 2.7 1.2 4.0 4.3 6.7 3.6 3.3 5.2 2.9 5.2 2.7 2.3 3.9 4.3 6.0 4.3 6.6 2.0 3.9 3.3 1.6 4.3 4.5 3.0 4.4 4.3 2.6 1.6 2.1 3.9 3.8 5.3 1.4 1.8 0.4 3.1 2.8 2.6 1.2 4.5 2.6 1.6 5.8 2.4 4.3 0.9 0.0 5.0 6.0 7.4 3.1 8.8 6.2 5.7 7.0 6.7 5.9 7.5 7.7 0.6 6.8 3.6 6.7 3.8 5.3 1.3 1.5 1.5 2.2 1.5 1.6 1.6 1.5 2.5 1.3 1.4 2.8 3.0 9.6 7.3 14.4 4.6 4.5 5.0 11.0 5.2 8.3 7.1 11.7 5.9 10.0 7.5 5.5 8.4 7.7 8.0 1.6 9.8 4.6 31.3 5.7 5.2 3.2 4.2 3.4 18.8 6.3 3.1 6.0 1.5 11.6 2.5 8.1 3.6 6.3 4.8 5.0 20.3 2.6 14.2 2.1 4.3 5.4 5.3 3.0 5.4 4.7 6.1 8.8 5.2 12.5 29.4 3.7 3.8 5.7 3.3 3.5 3.0 7.7 8.3 11.4 0.0 5.6 8.6 37.5 20.6 5.5 4.7 9.6 6.9 10.8 4.3 3.5 RAI14 "DKFZp564G013, KIAA1334, NORPEG, RAI13" ENSG00000039560 "Retinoic acid induced 14" Q9P0K7 5 34656328-34832612 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 208.2;Early spermatids: 210.1;Late spermatids: 364.3;Syncytiotrophoblasts: 156.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 267.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 23.8" "HPA036949, HPA036950" Supported Supported "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm "Actin filaments, Cytosol" "HPA036949: AB_10670568, HPA036950: AB_10669721" "unprognostic (7.63e-2)" "unprognostic (9.86e-2)" "unprognostic (4.87e-2)" "unprognostic (1.40e-1)" "unprognostic (3.38e-2)" "unprognostic (4.75e-2)" "unprognostic (5.49e-2)" "unprognostic (6.18e-2)" "unprognostic (6.28e-2)" "unprognostic (2.62e-1)" "unprognostic (8.18e-2)" "unprognostic (4.58e-2)" "prognostic unfavorable (9.75e-4)" "prognostic unfavorable (2.05e-4)" "unprognostic (1.33e-1)" "unprognostic (4.81e-2)" "unprognostic (4.34e-2)" 10.6 9.0 10.1 21.6 14.5 2.4 9.8 13.3 9.8 51.2 17.5 22.1 7.0 53.6 6.2 10.0 13.8 18.7 6.8 8.0 9.4 18.9 27.5 26.2 14.7 18.1 13.9 9.5 7.9 10.8 4.9 34.6 17.1 11.4 10.3 10.2 16.5 25.4 1.9 19.5 7.5 58.0 15.6 39.4 10.8 39.2 12.7 6.3 10.1 2.3 10.2 43.0 14.3 20.0 12.5 48.5 55.2 37.1 29.0 100.9 70.3 147.0 118.3 83.3 83.0 36.7 15.6 2.9 57.0 72.5 90.5 8.2 64.0 109.0 179.2 0.2 30.5 20.6 43.3 22.9 90.0 0.5 1.9 94.8 34.0 149.4 118.1 136.7 267.4 4.6 29.4 1.0 110.1 10.0 2.3 0.7 43.3 7.8 47.0 18.2 84.1 0.6 97.4 70.1 14.4 7.9 86.8 12.8 39.5 80.5 14.9 2.3 173.2 134.1 71.7 33.5 65.1 3.1 0.1 0.4 113.5 0.4 53.5 0.9 0.2 0.1 0.9 0.0 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.4 0.8 0.0 0.1 0.0 0.0 10.1 14.5 13.3 9.8 8.0 9.4 18.1 13.9 17.1 15.6 12.7 20.0 16.2 105.8 208.2 33.3 0.9 12.0 32.2 46.7 23.9 3.2 27.8 9.9 5.2 7.2 81.8 35.0 68.8 32.3 0.6 17.9 7.9 36.1 210.1 35.7 36.1 96.1 1.8 2.7 6.6 28.5 75.3 25.0 11.2 36.1 3.8 22.7 17.2 23.0 7.2 15.2 6.0 1.1 16.2 1.6 4.3 364.3 72.1 4.6 5.4 15.0 1.0 19.3 0.0 31.2 60.1 53.3 5.1 31.6 0.1 26.6 6.3 25.3 24.8 5.1 0.0 6.0 33.4 9.0 9.2 6.4 15.8 156.1 3.4 11.4 2.6 61.5 RFLNB "Cfm1, FAM101B, MGC45871, RefilinB" ENSG00000183688 "Refilin B" Q8N5W9 17 439978-445939 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 77.9" "Cell type enhanced" "Detected in many" "Adipocytes: 101.3;Endothelial cells: 51.1;Hofbauer cells: 38.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 201.5" "Lineage enriched" "Detected in many" 21 "granulocytes: 201.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 95.5;HMC-1: 222.1;NB-4: 74.8;U-937: 64.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030879, HPA060388" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Actin filaments" "Plasma membrane, Cytosol" "HPA030879: AB_2673643, HPA060388: AB_2732649" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (2.87e-1)" "unprognostic (3.14e-1)" "unprognostic (3.52e-2)" "unprognostic (2.34e-1)" "unprognostic (1.31e-1)" "unprognostic (1.48e-1)" "unprognostic (1.94e-1)" "unprognostic (2.87e-2)" "unprognostic (2.48e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (1.54e-4)" "unprognostic (3.45e-2)" "unprognostic (9.22e-2)" "unprognostic (1.43e-1)" "unprognostic (9.03e-3)" 19.8 5.9 2.4 7.4 2.5 77.9 15.6 2.3 2.8 8.7 10.1 13.7 3.2 10.1 3.5 3.1 7.1 4.6 12.8 3.3 2.2 8.6 3.5 13.3 5.4 2.5 2.4 5.7 3.5 3.9 4.3 10.4 2.2 9.5 1.9 1.5 4.1 2.8 7.9 6.3 9.6 6.1 2.7 10.5 8.6 3.7 2.4 16.7 8.2 3.9 4.8 11.8 5.4 2.1 30.5 8.0 4.0 18.9 13.0 9.4 20.8 48.8 21.4 15.8 7.7 0.5 1.1 0.0 1.2 95.5 7.0 3.0 11.2 1.1 14.5 0.2 6.5 1.3 1.5 2.2 19.0 11.4 222.1 5.2 0.3 5.0 1.9 6.1 16.0 4.8 4.7 0.3 18.1 0.4 0.6 74.8 8.6 0.8 0.3 3.2 8.6 0.0 2.9 0.1 0.3 43.6 19.8 0.0 17.6 14.9 0.4 34.7 3.2 12.4 11.0 7.5 0.1 7.1 7.7 0.0 0.2 64.1 19.5 201.5 6.9 80.7 6.1 5.4 6.2 0.1 6.1 5.2 2.1 0.1 9.7 8.7 35.5 2.2 7.3 9.1 4.3 3.8 2.4 2.5 2.3 2.8 3.3 2.2 2.5 2.4 2.2 2.7 2.4 2.1 101.3 0.0 4.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 3.1 7.4 0.0 0.0 1.8 1.8 0.0 0.8 16.5 0.0 0.0 1.1 0.0 2.3 1.9 51.1 0.0 0.0 0.0 0.9 1.2 9.2 0.0 6.0 1.3 12.5 0.0 0.0 38.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 5.7 0.0 0.0 0.0 0.0 1.9 0.0 0.0 5.9 0.0 0.0 0.5 1.5 0.0 0.0 0.0 16.2 0.0 0.0 0.0 0.0 0.5 10.7 4.2 0.0 0.0 RGS22 "CT145, DKFZP434I092, PRTD-NY2" ENSG00000132554 "Regulator of G protein signaling 22" Q8NE09 8 99960936-100131268 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 61.3" "Group enriched" "Detected in many" 8 "Early spermatids: 619.6;Late spermatids: 1623.3" "Cancer enhanced" "Detected in some" "breast cancer: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RPMI-8226: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA053026 Supported "Nucleoli fibrillar center,Actin filaments,Cytosol" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoli fibrillar center" "Actin filaments, Cytosol" "HPA053026: " "unprognostic (3.04e-2)" "unprognostic (2.62e-2)" "unprognostic (4.61e-2)" "unprognostic (3.97e-1)" "unprognostic (3.47e-5)" "unprognostic (1.61e-1)" "unprognostic (2.32e-1)" "unprognostic (3.19e-2)" "unprognostic (1.47e-1)" "unprognostic (1.14e-2)" "unprognostic (1.05e-2)" "unprognostic (7.96e-3)" "unprognostic (1.98e-5)" "unprognostic (3.71e-2)" "unprognostic (1.31e-2)" "unprognostic (3.25e-3)" "unprognostic (8.36e-4)" 2.7 0.9 1.7 0.0 2.4 0.0 0.6 1.0 1.5 1.4 10.4 0.3 0.0 2.9 1.1 0.3 10.6 1.2 0.3 1.1 3.9 0.2 0.1 1.7 0.3 5.9 7.4 7.3 0.5 0.0 1.1 0.5 3.7 1.3 0.1 1.0 0.1 2.3 0.1 0.6 0.1 1.5 3.7 0.0 0.1 61.3 5.3 0.1 0.3 0.1 0.3 0.4 0.5 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.9 0.6 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.0 0.1 0.0 0.3 1.3 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.4 1.0 1.5 1.1 3.9 5.9 7.4 3.7 3.7 5.3 2.9 0.1 0.0 0.0 14.4 0.0 2.2 0.0 1.6 0.6 1.2 1.2 0.8 0.8 0.0 12.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 619.6 58.1 14.2 0.7 0.0 0.0 2.3 0.0 0.2 8.6 0.5 0.8 0.0 1.3 0.0 0.0 0.2 0.0 1.6 0.0 4.1 0.0 2.9 1623.3 131.4 0.4 0.0 6.5 0.0 10.9 0.0 20.1 2.5 0.0 0.0 62.8 0.0 0.0 0.0 0.0 77.2 0.2 0.0 0.4 1.6 70.9 11.1 0.1 2.0 0.8 0.4 8.3 0.0 0.1 RGS7BP R7BP ENSG00000186479 "Regulator of G protein signaling 7 binding protein" Q6MZT1 5 64506015-64612319 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.0" "Group enriched" "Detected in some" 5 "Excitatory neurons: 122.5;Inhibitory neurons: 170.6;Oligodendrocyte precursor cells: 67.8" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "cerebral cortex: 26.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "HUVEC TERT2: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039600 Approved Uncertain "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Actin filaments" "HPA039600: AB_2676591" "unprognostic (2.93e-1)" "unprognostic (3.39e-1)" "unprognostic (7.35e-2)" "unprognostic (4.77e-2)" "unprognostic (7.57e-2)" "unprognostic (8.59e-2)" "unprognostic (5.22e-2)" "unprognostic (8.81e-3)" "unprognostic (1.86e-2)" "unprognostic (7.64e-2)" "unprognostic (5.49e-3)" "unprognostic (1.83e-1)" "unprognostic (1.65e-3)" "unprognostic (3.39e-3)" "unprognostic (2.06e-3)" "unprognostic (6.46e-2)" "unprognostic (8.50e-3)" 1.9 3.2 3.2 0.5 12.2 0.0 0.5 1.0 26.0 4.0 0.0 0.6 0.9 2.3 3.7 1.7 7.8 1.7 2.6 7.2 1.2 2.0 1.0 1.4 0.3 0.2 3.3 2.4 0.2 0.1 0.8 0.0 0.0 5.3 0.7 4.8 1.8 7.4 0.1 0.3 1.0 1.4 0.0 0.7 0.8 0.8 10.2 0.0 0.3 1.0 0.1 0.9 0.5 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 12.2 1.0 26.0 7.2 1.2 0.2 3.3 0.0 0.0 10.2 5.0 0.4 0.0 0.0 5.5 0.1 0.0 0.1 0.1 0.6 6.5 0.7 1.1 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 2.1 5.1 4.6 0.0 2.7 122.5 0.0 0.0 0.8 0.0 4.7 0.0 0.1 23.2 0.1 0.0 0.0 170.6 0.0 0.0 0.3 0.0 1.9 7.2 0.1 0.0 12.2 0.0 3.6 0.0 67.8 6.4 0.0 0.0 13.9 0.0 0.1 0.0 0.2 2.2 2.1 6.6 0.1 13.2 0.3 0.6 0.4 0.0 0.0 0.2 0.0 0.0 0.2 RND1 "ARHS, Rho6, RHOS" ENSG00000172602 "Rho family GTPase 1" Q92730 12 48857145-48865870 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 131.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 205.5;Ductal cells: 220.6;Exocrine glandular cells: 147.1;Pancreatic endocrine cells: 350.9" "Cancer enhanced" "Detected in many" "liver cancer: 16.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "SK-BR-3: 67.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077800 Supported "Vesicles,Plasma membrane,Actin filaments" NA NA "Cluster 30: Non-specific - Translation" "Cluster 15: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "Vesicles, Plasma membrane, Actin filaments" "HPA077800: AB_2686854" "unprognostic (5.60e-2)" "unprognostic (3.21e-2)" "unprognostic (2.23e-1)" "unprognostic (1.16e-1)" "unprognostic (6.90e-2)" "unprognostic (1.32e-3)" "unprognostic (3.59e-2)" "unprognostic (7.43e-2)" "unprognostic (2.21e-3)" "unprognostic (2.97e-1)" "unprognostic (1.93e-1)" "unprognostic (1.66e-1)" "unprognostic (3.89e-1)" "unprognostic (8.38e-3)" "unprognostic (6.18e-2)" "unprognostic (6.60e-2)" "unprognostic (3.35e-3)" 9.6 0.8 24.4 2.6 26.9 1.8 5.6 18.9 40.6 1.6 15.4 4.8 2.4 3.9 1.0 3.1 2.7 14.5 7.3 26.8 20.4 4.4 131.8 37.9 1.0 21.4 23.6 1.2 2.8 2.4 8.0 1.2 21.9 6.5 1.9 1.7 3.9 0.8 1.0 1.6 2.6 2.4 19.9 0.8 23.4 0.9 22.1 2.4 15.4 0.6 2.3 14.0 2.7 23.2 1.1 7.9 3.8 2.0 0.8 0.0 0.6 0.0 0.4 1.2 1.3 4.9 1.7 6.0 1.4 0.0 0.4 0.1 3.1 0.3 0.7 1.8 1.9 0.8 0.0 3.0 0.4 1.8 1.1 0.0 0.2 0.6 0.8 0.0 2.0 3.9 0.2 6.0 0.0 10.2 0.9 0.5 8.9 13.6 0.5 1.9 0.4 2.6 1.1 1.5 0.0 1.0 0.2 67.7 0.3 9.1 6.9 0.4 0.2 0.0 0.7 0.0 0.9 2.9 5.4 10.9 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 24.4 26.9 18.9 40.6 26.8 20.4 21.4 23.6 21.9 19.9 22.1 23.2 28.9 28.9 205.5 5.9 8.5 11.5 8.4 14.1 9.1 2.5 37.5 25.4 3.8 18.6 27.5 1.8 8.4 1.1 9.0 21.7 0.0 220.6 0.4 4.5 2.0 87.3 31.5 2.7 10.6 147.1 0.7 10.5 55.5 12.6 15.2 0.8 6.1 10.9 1.2 0.0 2.7 11.4 18.3 0.8 24.1 0.0 0.0 6.6 14.2 1.0 6.4 3.0 0.0 7.1 1.0 350.9 42.2 0.4 6.5 19.5 11.1 1.7 7.7 3.6 0.0 5.8 16.7 0.8 1.6 4.3 10.5 1.5 9.9 0.6 5.4 8.6 RNF25 "AO7, FLJ13906" ENSG00000163481 "Ring finger protein 25" Q96BH1 2 218663892-218672002 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036420, HPA036421" Uncertain Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "Nucleoplasm, Actin filaments" "HPA036420: AB_2675114, HPA036421: AB_10669604" "unprognostic (3.22e-2)" "unprognostic (7.85e-3)" "unprognostic (1.34e-2)" "unprognostic (2.29e-2)" "unprognostic (1.33e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (6.58e-4)" "unprognostic (3.58e-2)" "unprognostic (2.67e-2)" "unprognostic (3.46e-1)" "unprognostic (2.04e-3)" "unprognostic (8.82e-2)" "unprognostic (1.26e-3)" "unprognostic (2.50e-1)" "unprognostic (1.37e-1)" "unprognostic (2.44e-1)" "unprognostic (6.69e-2)" 10.9 11.4 18.5 8.9 18.6 7.3 10.9 18.3 21.0 12.2 17.1 12.0 6.2 12.7 15.8 11.7 12.4 10.8 13.9 18.6 19.7 10.4 11.1 10.4 14.5 18.4 18.4 14.5 11.5 15.1 11.4 11.4 19.0 11.8 8.2 7.0 11.0 13.9 15.0 14.5 7.9 13.6 18.5 10.3 9.4 14.3 19.2 15.1 14.1 17.1 11.9 14.0 9.7 19.0 18.8 20.4 22.1 24.6 27.6 17.5 20.4 27.3 43.5 58.0 53.6 32.4 13.2 11.6 17.6 42.3 35.2 19.5 22.1 33.9 31.0 16.4 27.3 22.7 21.3 34.6 33.6 19.3 20.6 33.9 30.9 55.5 44.7 21.4 31.0 40.9 27.4 24.3 41.1 45.3 20.6 20.4 32.9 16.2 23.4 23.2 15.5 15.9 36.3 21.8 19.5 23.8 18.1 17.2 28.4 21.9 20.6 25.6 26.6 40.2 20.5 19.2 31.1 23.7 13.7 23.5 33.4 19.1 25.7 58.6 21.5 32.6 26.0 21.3 24.8 25.7 25.7 27.2 17.1 30.4 29.0 23.2 17.1 30.5 25.2 15.0 25.9 24.8 18.5 18.6 18.3 21.0 18.6 19.7 18.4 18.4 19.0 18.5 19.2 19.0 4.2 0.0 0.5 5.2 7.8 6.2 4.8 16.3 6.8 7.7 3.4 3.7 4.0 10.0 8.9 1.8 8.4 12.3 4.5 7.4 15.6 12.3 16.8 6.3 8.1 7.6 1.2 2.1 6.2 12.9 9.7 7.5 9.7 4.8 7.0 5.9 8.9 7.1 13.2 5.0 5.8 5.5 8.2 5.0 4.0 5.3 7.2 5.5 8.8 2.8 8.9 7.9 9.2 3.5 4.9 12.7 9.6 12.8 8.5 3.8 7.2 14.8 8.2 5.0 26.3 5.6 9.2 19.3 12.8 5.9 6.8 10.0 8.0 8.5 6.1 3.6 RTN4R NOGOR ENSG00000040608 "Reticulon 4 receptor" Q9BZR6 22 20241415-20283246 "Disease related genes, Human disease related genes, Predicted membrane proteins" Receptor "Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.3;liver: 12.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 12.1;Excitatory neurons: 14.1;Muller glia cells: 11.3" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 10 "amygdala: 8.0;basal ganglia: 20.0;cerebellum: 20.9;cerebral cortex: 24.3;hippocampal formation: 12.7" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 10.8" "Lineage enriched" "Detected in many" 9 "T-cells: 10.8" "Cell line enhanced" "Detected in many" "NB-4: 38.2;REH: 53.9;SCLC-21H: 31.3;SK-MEL-30: 25.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB012443 Supported "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 1900000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane, Focal adhesion sites" "Actin filaments" "CAB012443: " "unprognostic (1.28e-1)" "unprognostic (1.28e-2)" "unprognostic (8.29e-2)" "unprognostic (6.58e-2)" "unprognostic (3.49e-1)" "prognostic unfavorable (7.73e-4)" "unprognostic (2.19e-1)" "unprognostic (1.56e-1)" "unprognostic (3.44e-1)" "unprognostic (8.90e-3)" "unprognostic (1.21e-2)" "unprognostic (9.89e-2)" "unprognostic (1.80e-2)" "unprognostic (1.34e-2)" "unprognostic (1.30e-1)" "unprognostic (5.02e-2)" "unprognostic (3.07e-1)" 1.6 2.6 8.0 0.5 20.0 0.6 1.0 20.9 24.3 3.6 0.0 1.6 2.2 5.1 0.0 3.5 1.9 0.1 2.7 12.7 0.0 2.1 12.8 2.2 0.4 0.5 0.0 2.4 3.7 0.4 4.9 0.4 0.3 1.5 0.1 0.6 2.0 0.4 0.6 7.9 2.1 0.2 0.0 8.5 1.8 1.9 0.4 0.8 3.5 0.2 0.2 0.5 2.8 1.8 7.9 3.8 2.3 5.5 0.0 0.0 1.2 0.8 0.0 0.6 0.3 6.0 2.2 0.4 2.5 0.1 3.7 12.8 1.4 3.2 0.0 0.2 13.4 0.1 3.2 0.9 1.3 0.3 0.4 0.0 4.1 0.0 0.3 0.0 0.0 3.7 0.4 0.3 0.0 11.0 4.1 38.2 8.7 2.3 6.7 53.9 0.0 0.4 0.5 3.3 31.3 5.0 3.7 2.7 25.9 0.5 3.1 1.1 0.0 0.5 14.2 0.1 0.2 0.1 1.0 0.9 0.4 7.8 0.1 0.0 0.0 0.0 4.6 0.0 10.8 0.0 4.0 4.6 0.2 0.1 2.4 5.1 0.0 0.8 0.0 1.2 3.0 1.7 8.0 20.0 20.9 24.3 12.7 0.0 0.5 0.0 0.3 0.0 0.4 1.8 1.4 3.2 0.0 7.5 0.2 5.1 4.0 1.6 1.8 12.1 2.9 2.4 2.2 0.0 0.6 0.0 4.2 0.2 1.9 3.0 0.0 2.9 2.0 1.2 4.8 2.0 0.0 0.4 14.1 4.3 7.6 1.6 0.0 1.6 0.0 0.4 1.1 3.0 1.3 6.7 2.6 2.6 0.0 0.0 0.7 0.5 0.3 1.7 1.8 2.8 0.7 11.3 2.1 2.5 2.4 3.4 0.4 0.0 0.1 3.9 0.6 0.0 0.0 4.9 0.0 0.2 1.0 0.1 1.2 2.0 5.5 0.0 2.5 0.1 2.1 3.5 SCN9A "ETHA, Nav1.7, NE-NA, NENA, PN1" ENSG00000169432 "Sodium voltage-gated channel alpha subunit 9" Q15858 2 166195185-166376001 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 21.9" "Cell type enhanced" "Detected in many" "dendritic cells: 43.2;Hofbauer cells: 67.5;Inhibitory neurons: 48.2;Langerhans cells: 42.8;Oligodendrocyte precursor cells: 133.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 23.6" "Lineage enriched" "Detected in single" 26 "dendritic cells: 23.6" "Cell line enhanced" "Detected in many" "BJ: 23.0;BJ hTERT+: 16.8;HHSteC: 19.0;hTERT-RPE1: 15.6" "Region enriched" "Detected in many" 5 "hypothalamus: 9.3" "Low region specificity" "Detected in many" "CAB013679, HPA061843" Uncertain Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Actin filaments, Focal adhesion sites" "CAB013679: , HPA061843: AB_2684625" "unprognostic (2.10e-1)" "unprognostic (2.83e-1)" "unprognostic (1.13e-1)" "unprognostic (8.98e-5)" "unprognostic (1.47e-3)" "unprognostic (9.43e-3)" "unprognostic (2.28e-2)" "unprognostic (2.24e-1)" "unprognostic (2.23e-1)" "unprognostic (3.64e-1)" "unprognostic (1.45e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.30e-5)" "unprognostic (1.69e-3)" "unprognostic (6.74e-2)" "unprognostic (2.46e-2)" "unprognostic (2.46e-1)" 1.7 1.7 5.3 0.9 4.2 2.0 0.6 0.1 3.4 0.6 0.0 3.2 0.5 0.2 0.1 0.5 0.4 1.2 0.4 2.9 21.9 1.7 3.9 2.0 0.6 8.2 19.4 0.3 2.0 0.1 1.5 4.3 12.0 0.3 3.1 0.7 0.4 0.4 0.2 0.7 1.8 2.4 2.2 3.1 0.4 5.1 18.2 1.6 0.3 0.6 0.4 0.5 0.5 1.7 0.0 2.5 0.1 0.0 9.6 7.9 0.0 23.0 16.8 5.2 1.7 0.5 0.1 0.0 0.0 2.8 0.2 0.1 6.5 0.6 8.6 0.0 2.1 1.7 1.8 1.9 19.0 0.1 0.0 0.6 0.2 9.1 1.7 15.6 1.1 1.2 6.1 6.6 0.8 0.0 3.6 0.0 1.9 0.1 0.6 0.8 3.3 9.0 2.4 9.5 1.0 9.5 0.0 0.1 0.3 4.8 0.3 0.0 0.1 0.0 1.5 0.1 0.4 0.1 0.1 0.0 3.2 0.0 2.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.9 0.5 0.1 23.6 0.0 0.1 5.3 4.2 0.1 3.4 2.9 21.9 8.2 19.4 12.0 2.2 18.2 1.7 0.9 12.8 23.8 0.7 1.3 1.0 0.4 0.5 0.6 0.6 0.8 0.9 2.5 8.6 4.4 5.5 0.0 0.3 43.2 9.0 3.9 23.4 2.5 0.1 0.1 5.7 33.0 4.2 15.8 31.5 0.3 2.0 0.0 0.1 3.8 18.1 13.6 9.5 67.5 0.0 48.2 19.3 10.2 1.9 42.8 3.2 1.2 11.3 3.6 2.8 1.0 2.3 0.0 133.7 0.4 12.7 7.8 0.0 1.2 0.3 14.7 11.5 2.2 0.2 0.0 7.8 1.6 1.3 0.4 0.5 0.4 1.1 0.9 4.4 12.9 0.2 SEC16B "LZTR2, PGPR-p117, RGPR, Sec16S" ENSG00000120341 "SEC16 homolog B, endoplasmic reticulum export factor" Q96JE7 1 177923956-177984303 "Predicted intracellular proteins" "ER-Golgi transport, Peroxisome biogenesis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 28.4;liver: 36.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 66.3;Late spermatids: 50.4;Proximal enterocytes: 34.8" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebral cortex: 2.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 6.6;CAPAN-2: 7.2;EFO-21: 5.4;HDLM-2: 5.8;Karpas-707: 4.8;RPMI-8226: 6.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA054292, HPA072913" Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Actin filaments" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum, Plasma membrane" "Actin filaments" "HPA054292: AB_2682439, HPA072913: AB_2732213" "unprognostic (2.31e-1)" "unprognostic (1.90e-1)" "unprognostic (6.78e-3)" "unprognostic (6.07e-2)" "unprognostic (1.69e-1)" "unprognostic (1.33e-1)" "unprognostic (6.39e-3)" "unprognostic (1.22e-1)" "unprognostic (2.27e-2)" "unprognostic (1.50e-2)" "unprognostic (4.76e-3)" "unprognostic (2.43e-1)" "unprognostic (7.34e-4)" "unprognostic (6.67e-2)" "unprognostic (1.66e-1)" "unprognostic (1.37e-1)" "unprognostic (1.05e-1)" 4.0 2.5 0.5 1.1 1.1 0.3 3.2 0.0 2.9 3.0 0.0 3.6 28.0 3.5 2.0 2.0 3.5 4.3 2.6 0.8 0.1 3.4 36.4 2.4 1.1 0.0 0.3 4.2 9.0 0.5 1.4 0.8 0.1 1.6 4.0 5.7 3.6 2.1 9.3 2.7 28.4 2.7 0.0 5.8 8.7 1.4 0.3 0.4 2.1 3.1 0.9 1.4 1.1 1.2 1.9 1.5 0.1 1.5 1.9 6.6 0.0 1.5 0.5 0.1 0.7 1.0 7.2 0.6 5.4 1.2 0.1 0.0 0.4 0.2 0.0 5.8 0.1 0.0 0.0 3.4 0.1 0.1 0.0 3.8 0.5 0.2 0.0 0.2 2.2 0.0 0.0 4.8 3.9 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.6 6.5 0.1 0.1 0.6 1.2 0.1 0.2 0.8 0.0 0.1 1.3 0.7 1.0 0.2 0.6 0.0 1.5 0.7 0.1 2.6 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.1 0.0 2.9 0.8 0.1 0.0 0.3 0.1 0.0 0.3 1.2 7.7 0.0 2.0 2.9 0.7 0.3 0.3 0.4 1.8 1.3 6.3 1.8 0.5 7.2 1.9 1.8 2.1 0.5 0.0 0.9 0.0 0.6 10.1 2.3 1.6 3.9 3.6 0.0 15.8 1.1 0.0 1.9 9.2 2.7 1.3 1.9 3.6 66.3 0.6 11.8 4.8 4.6 0.0 3.2 0.4 50.4 2.5 0.7 1.8 3.7 0.6 1.4 0.0 1.0 1.3 1.1 5.2 1.2 2.9 0.1 34.8 3.1 3.3 4.7 0.0 2.7 1.0 0.3 0.8 0.6 1.0 0.0 0.3 0.1 5.4 0.2 SEPTIN3 "SEP3, SEPT3" ENSG00000100167 "Septin 3" Q9UH03 22 41969475-41998221 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 233.7" "Cell type enriched" "Detected in some" 5 "Extravillous trophoblasts: 27.9" "Group enriched" "Detected in many" 5 "glioma: 24.6;melanoma: 11.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 26.6;Daudi: 22.3;SCLC-21H: 71.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003548, CAB017633" Supported Supported Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Plasma membrane" "Actin filaments" "CAB017633: AB_2301476, HPA003548: AB_1079908" "unprognostic (2.10e-1)" "unprognostic (4.67e-2)" "unprognostic (1.16e-2)" "prognostic unfavorable (1.78e-4)" "unprognostic (4.56e-2)" "unprognostic (1.13e-1)" "unprognostic (7.07e-3)" "unprognostic (2.37e-1)" "unprognostic (2.67e-3)" "unprognostic (3.09e-2)" "unprognostic (1.30e-2)" "unprognostic (6.30e-2)" "unprognostic (2.51e-2)" "unprognostic (9.15e-2)" "unprognostic (6.68e-2)" "unprognostic (5.50e-2)" "unprognostic (1.04e-1)" 0.2 4.6 134.7 0.4 160.5 0.1 1.3 82.4 233.7 0.2 30.5 0.8 0.3 0.2 1.4 0.2 0.1 0.4 0.2 167.0 89.5 0.3 0.1 0.7 0.5 86.2 73.4 0.2 1.2 18.6 7.8 5.7 83.8 1.3 0.5 28.4 0.4 0.0 0.1 1.6 0.4 0.3 56.9 0.2 0.7 2.1 91.4 0.9 0.8 0.2 0.5 0.3 0.4 150.7 1.5 1.7 26.6 20.1 0.3 0.0 13.3 0.3 0.3 1.8 0.8 0.4 3.1 22.3 0.7 0.2 11.4 0.1 14.0 0.1 0.7 9.2 4.6 0.1 0.5 0.0 0.2 0.0 0.9 0.2 1.0 0.1 0.0 0.0 0.0 12.1 0.0 3.4 0.0 2.4 3.7 0.2 18.2 0.2 0.7 17.9 0.0 1.3 0.0 2.7 71.4 14.8 10.9 0.1 18.2 2.5 2.6 6.7 0.0 0.0 9.2 0.9 1.0 14.1 13.1 0.2 0.3 9.0 2.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 134.7 160.5 82.4 233.7 167.0 89.5 86.2 73.4 83.8 56.9 91.4 150.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 SEPTIN5 "H5, HCDCREL-1, PNUTL1, SEPT5" ENSG00000184702 "Septin 5" Q99719 22 19714503-19724224 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 321.9" "Group enriched" "Detected in some" 9 "Cardiomyocytes: 3.4;Smooth muscle cells: 2.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 32 "eosinophil: 15.4;neutrophil: 5.8" "Lineage enriched" "Detected in single" 47 "granulocytes: 15.4" "Cell line enhanced" "Detected in many" "K-562: 281.6;THP-1: 75.9" "CAB016120, HPA029095, HPA063885" Enhanced Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA 860000 "Cluster 49: Eosinophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nucleoplasm, Actin filaments, Cytosol" "CAB016120: AB_628240, HPA029095: AB_2672904, HPA063885: AB_2685141" "unprognostic (4.07e-2)" "unprognostic (1.47e-1)" "unprognostic (6.78e-3)" "unprognostic (1.39e-2)" "unprognostic (3.92e-1)" "unprognostic (1.86e-1)" "unprognostic (2.50e-2)" "unprognostic (3.77e-1)" "unprognostic (5.66e-2)" "unprognostic (6.19e-2)" "unprognostic (1.88e-3)" "unprognostic (4.34e-1)" "prognostic unfavorable (6.87e-6)" "unprognostic (3.39e-2)" "unprognostic (2.93e-1)" "unprognostic (1.53e-2)" "unprognostic (3.30e-2)" 17.7 17.7 152.8 5.7 215.6 41.0 16.4 49.2 321.9 54.1 61.9 19.8 5.2 28.1 46.2 62.1 38.8 14.7 165.4 233.6 49.3 12.7 5.2 17.4 8.4 40.9 45.2 29.3 17.0 127.3 82.7 12.0 39.4 20.1 6.3 30.3 15.9 9.9 10.8 126.5 8.8 17.3 24.7 14.3 16.3 29.1 73.1 15.9 33.4 16.2 8.1 13.5 42.8 168.6 0.4 10.6 42.0 64.0 3.9 13.1 0.3 15.8 20.1 17.9 10.5 0.7 5.6 1.5 6.1 35.8 26.0 6.0 30.2 6.0 8.8 9.6 3.4 0.7 2.4 0.2 16.2 0.8 47.2 17.4 7.4 6.0 2.5 5.1 7.5 23.1 281.6 0.6 28.2 4.2 4.6 31.2 5.4 1.0 10.4 41.4 1.3 7.2 1.3 1.4 62.3 49.2 2.4 3.5 2.8 10.2 17.3 75.9 3.0 46.4 55.6 2.0 3.2 4.5 0.0 0.4 5.8 2.2 15.2 0.0 0.1 15.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 5.8 0.0 0.0 0.3 0.0 6.0 152.8 215.6 49.2 321.9 233.6 49.3 40.9 45.2 39.4 24.7 73.1 168.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SIGLEC10 "MGC126774, PRO940, SIGLEC-10, SLG2" ENSG00000142512 "Sialic acid binding Ig like lectin 10" Q96LC7 19 51410020-51417803 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 38.5" "Cell type enhanced" "Detected in some" "B-cells: 33.0;granulocytes: 39.3;Kupffer cells: 93.9;Macrophages: 51.5" "Cancer enhanced" "Detected in all" "glioma: 11.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 765.3;intermediate monocyte: 252.0;non-classical monocyte: 539.2" "Group enriched" "Detected in many" 16 "granulocytes: 765.3;monocytes: 539.2" "Cell line enhanced" "Detected in some" "Daudi: 28.8;HDLM-2: 9.0;HEL: 14.9;HMC-1: 10.7;NB-4: 10.4;U-698: 21.3;U-937: 12.0" "Not detected" "Not detected" "CAB025807, HPA027093" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Cytosol "Plasma membrane, Actin filaments" "CAB025807: , HPA027093: AB_1856858" "unprognostic (7.18e-2)" "unprognostic (3.90e-3)" "unprognostic (1.11e-2)" "unprognostic (3.67e-2)" "unprognostic (3.95e-2)" "unprognostic (9.41e-2)" "unprognostic (8.18e-2)" "unprognostic (2.11e-1)" "unprognostic (3.16e-2)" "unprognostic (1.83e-1)" "unprognostic (1.63e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.73e-1)" "unprognostic (1.69e-2)" "unprognostic (1.39e-1)" "unprognostic (9.05e-2)" 3.5 6.4 3.9 33.9 4.8 14.9 2.1 4.3 6.0 2.1 3.5 5.4 7.0 2.1 1.0 2.0 2.4 3.7 1.4 3.9 6.2 1.7 3.2 8.5 19.9 11.4 6.9 1.6 3.5 1.0 1.4 1.8 8.8 3.0 4.6 1.1 2.2 1.1 0.7 1.2 12.2 4.5 6.3 38.5 4.7 1.3 6.3 4.0 1.0 1.1 19.5 5.5 1.2 9.4 0.2 0.0 0.5 0.5 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.1 1.3 28.8 0.9 0.1 0.3 0.5 0.0 0.2 0.0 9.0 2.5 14.9 0.3 0.1 0.0 6.4 10.7 0.1 0.0 0.1 0.0 0.1 0.0 1.7 0.7 1.4 0.0 0.6 0.2 10.4 0.8 0.7 0.4 1.9 0.1 0.5 0.0 0.3 0.4 0.4 0.3 0.1 0.2 0.5 0.1 5.2 0.7 0.7 1.3 0.6 0.2 1.3 0.3 21.3 0.5 12.0 0.5 14.0 41.9 765.3 0.8 252.0 0.4 41.4 0.5 0.5 38.0 27.4 0.3 0.5 87.2 0.4 539.2 2.2 1.1 40.7 3.9 4.8 4.3 6.0 3.9 6.2 11.4 6.9 8.8 6.3 6.3 9.4 0.7 3.2 1.3 0.3 33.0 0.1 1.2 0.0 0.0 1.4 0.4 0.9 0.3 0.0 0.0 1.8 2.1 0.1 0.6 0.1 0.0 0.0 0.9 0.0 0.0 4.2 0.0 5.2 0.6 0.0 0.1 0.8 0.0 0.1 39.3 0.1 0.4 1.0 8.1 0.0 0.2 0.1 0.0 93.9 6.3 0.4 0.0 51.5 0.0 15.0 14.8 0.2 6.2 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.1 0.0 0.7 0.0 2.0 0.4 0.5 0.7 0.0 1.3 0.1 2.7 0.1 0.0 0.9 SLC46A3 "DKFZp686A1775, FLJ42613" ENSG00000139508 "Solute carrier family 46 member 3" Q7Z3Q1 13 28700064-28718970 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 76.0;liver: 96.0" "Cell type enhanced" "Detected in many" "Granulosa cells: 53.2;Hepatocytes: 51.3;Proximal enterocytes: 125.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 27.0;T-47d: 20.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039930 Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "Actin filaments" "HPA039930: AB_10673263" "unprognostic (5.16e-2)" "unprognostic (1.01e-1)" "unprognostic (1.15e-1)" "unprognostic (2.61e-1)" "unprognostic (3.88e-1)" "unprognostic (1.22e-1)" "unprognostic (4.53e-3)" "prognostic favorable (7.09e-4)" "unprognostic (3.13e-1)" "unprognostic (3.33e-1)" "unprognostic (1.26e-1)" "unprognostic (5.69e-2)" "unprognostic (7.35e-2)" "unprognostic (1.14e-1)" "unprognostic (5.60e-2)" "unprognostic (9.14e-3)" "unprognostic (6.47e-3)" 13.8 11.7 5.1 10.2 5.7 2.9 10.0 7.7 5.2 14.7 10.0 19.8 46.7 5.6 11.1 4.0 7.5 23.8 12.3 4.7 5.7 18.2 96.0 11.5 16.3 5.9 6.0 3.9 6.7 23.9 10.2 9.5 6.1 6.5 18.8 15.9 9.0 9.9 8.5 4.2 76.0 8.2 6.6 18.2 7.8 11.0 6.6 11.6 12.5 8.6 11.1 7.0 2.2 5.6 0.0 2.8 0.0 7.6 6.0 2.3 0.2 2.7 15.7 3.0 4.4 0.1 6.6 5.2 4.7 4.0 11.5 0.6 3.5 1.4 4.5 3.9 6.2 3.6 0.0 0.0 11.4 0.0 4.3 9.8 2.9 4.5 7.3 3.0 5.6 15.7 3.9 0.0 14.5 3.0 8.6 0.6 0.3 8.0 2.2 3.5 13.3 0.2 27.0 0.9 1.2 0.4 0.0 14.1 5.7 3.1 20.6 4.6 2.0 1.4 2.7 0.4 16.0 4.0 2.0 0.8 0.9 0.0 2.8 33.1 8.9 3.8 10.3 13.1 8.6 7.4 8.0 10.1 11.7 9.7 11.4 10.8 9.8 7.0 19.4 11.0 10.6 8.7 5.1 5.7 7.7 5.2 4.7 5.7 5.9 6.0 6.1 6.6 6.6 5.6 6.2 0.0 5.4 16.0 14.5 1.9 0.1 7.4 1.8 33.7 15.1 3.3 9.6 17.2 15.6 9.2 8.4 0.6 16.4 49.0 1.9 15.5 4.6 2.1 1.7 12.2 3.6 4.6 11.6 5.6 0.3 6.2 0.0 2.1 25.9 53.2 17.5 51.3 10.8 21.9 13.0 6.8 2.0 32.1 36.6 1.8 1.5 22.5 7.2 16.9 9.3 14.2 12.3 14.6 15.6 3.5 5.3 2.2 6.5 0.6 125.0 10.1 15.4 9.8 0.0 2.8 7.2 2.6 0.9 4.9 1.7 0.7 11.4 16.8 13.9 0.2 SRMS "C20orf148, dJ697K14.1, PTK70, SRM" ENSG00000125508 "Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites" Q9H3Y6 20 63540810-63547504 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "stomach 1: 1.6" "Cell type enriched" "Detected in single" 4 "Gastric mucus-secreting cells: 3.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.3;MCF7: 3.0;OE19: 4.4;RT4: 6.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB044668, CAB044669, HPA073987" Uncertain Approved "Intermediate filaments,Actin filaments,Cytosol" No NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 43: Cardiomyocytes - Nuclear processes" "Intermediate filaments" "Actin filaments, Cytosol" "CAB044668: AB_10609403, CAB044669: AB_10608235, HPA073987: AB_2686650" "unprognostic (2.26e-2)" "unprognostic (1.26e-2)" "unprognostic (2.52e-3)" "unprognostic (8.32e-2)" "unprognostic (2.62e-1)" "unprognostic (5.47e-3)" "unprognostic (1.65e-1)" "unprognostic (2.28e-1)" "unprognostic (9.63e-2)" "unprognostic (6.48e-3)" "unprognostic (7.28e-3)" "unprognostic (1.46e-1)" "unprognostic (1.73e-3)" "unprognostic (2.58e-3)" "unprognostic (4.75e-2)" "unprognostic (4.97e-2)" "unprognostic (2.54e-3)" 0.0 0.0 0.1 0.2 0.1 0.1 0.4 0.6 0.2 0.0 0.0 0.7 0.2 0.0 0.7 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.8 0.0 0.0 0.4 0.2 0.0 0.1 0.9 1.6 0.2 0.1 0.0 0.1 0.0 0.1 0.3 0.0 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.3 0.1 1.3 0.0 0.0 1.5 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.0 0.0 0.1 0.0 4.4 0.4 0.0 0.1 0.0 0.0 6.0 0.4 0.5 0.1 1.2 0.2 0.0 1.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 STOX2 DKFZp762K222 ENSG00000173320 "Storkhead box 2" Q9P2F5 4 183797692-184023526 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 181.7;Inhibitory neurons: 192.3;Microglial cells: 72.1;Oligodendrocyte precursor cells: 91.0;Oligodendrocytes: 153.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 13.2;HeLa: 12.7;NTERA-2: 16.8;SH-SY5Y: 15.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049776, HPA065002" Uncertain Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "Actin filaments" "HPA049776: AB_2680875, HPA065002: " "unprognostic (9.79e-3)" "unprognostic (3.46e-1)" "unprognostic (2.10e-1)" "unprognostic (6.57e-3)" "unprognostic (3.33e-1)" "unprognostic (6.41e-2)" "unprognostic (4.57e-4)" "unprognostic (8.97e-3)" "unprognostic (1.25e-1)" "unprognostic (1.86e-1)" "unprognostic (3.75e-2)" "unprognostic (1.86e-1)" "unprognostic (7.06e-2)" "unprognostic (1.64e-1)" "unprognostic (1.71e-1)" "unprognostic (2.52e-3)" "unprognostic (2.49e-1)" 1.8 1.6 8.3 0.7 8.2 6.0 1.8 4.2 13.3 2.1 2.3 1.7 0.9 1.9 3.4 5.0 2.7 1.3 3.6 11.1 3.1 2.7 2.0 2.1 0.6 2.7 3.9 3.3 4.9 4.0 7.0 1.4 3.9 2.3 0.9 3.8 7.3 2.3 2.1 3.9 1.3 1.8 2.0 4.1 2.3 0.9 6.6 4.1 5.8 2.1 1.1 2.5 3.3 11.5 2.1 4.3 13.2 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.3 1.7 0.0 2.6 0.0 2.7 0.2 7.4 1.2 0.0 0.0 5.9 0.0 12.7 0.1 0.0 0.8 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.5 0.0 1.8 0.0 0.6 0.0 0.1 16.8 0.0 0.6 0.1 4.8 0.0 3.1 4.1 6.8 15.8 3.2 0.0 0.0 4.7 0.2 0.4 0.0 0.0 2.8 0.0 0.1 0.1 3.8 2.1 0.6 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 8.2 4.2 13.3 11.1 3.1 2.7 3.9 3.9 2.0 6.6 11.5 12.7 12.8 22.1 39.2 0.4 4.2 6.0 3.7 8.6 28.2 3.8 4.6 20.7 5.7 8.7 7.3 0.0 2.7 0.0 0.2 3.9 5.4 1.2 7.2 0.7 18.5 1.8 0.0 181.7 3.1 2.1 5.8 3.1 3.7 0.0 0.3 21.4 5.6 1.1 33.7 192.3 0.4 2.0 2.2 1.5 2.6 0.6 0.8 1.8 72.1 0.0 12.4 0.0 91.0 153.5 2.1 0.0 4.5 1.3 5.2 0.0 4.0 16.8 3.4 0.0 4.8 4.5 0.6 2.0 17.8 3.3 0.7 0.7 3.6 0.4 3.4 STRN3 "PPP2R6B, S/G2NA, SG2NA" ENSG00000196792 "Striatin 3" Q13033 14 30893799-31026401 "Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003392, HPA004636, CAB069925" Approved Supported "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "Nucleoplasm, Actin filaments" "CAB069925: AB_1146988, HPA003392: AB_1079942, HPA004636: AB_1079940" "unprognostic (4.08e-1)" "unprognostic (8.66e-2)" "unprognostic (8.08e-2)" "unprognostic (4.22e-2)" "unprognostic (3.06e-2)" "unprognostic (7.74e-3)" "unprognostic (3.37e-2)" "unprognostic (2.83e-1)" "unprognostic (3.05e-1)" "unprognostic (9.53e-2)" "unprognostic (1.03e-1)" "unprognostic (1.61e-1)" "prognostic favorable (9.66e-4)" "unprognostic (8.74e-2)" "unprognostic (7.85e-2)" "unprognostic (4.83e-2)" "unprognostic (1.01e-2)" 18.9 13.4 8.4 9.3 8.3 10.0 11.6 14.9 11.2 14.0 8.9 16.1 7.3 12.4 13.8 15.3 9.9 12.4 18.5 7.5 16.4 13.9 21.5 10.0 7.5 7.7 9.8 10.1 12.6 13.9 9.3 11.9 7.5 13.7 12.6 14.2 10.3 14.1 39.2 11.7 9.7 18.0 6.0 10.4 11.2 20.9 10.7 9.4 13.7 28.5 9.0 14.7 11.6 10.6 33.7 29.2 31.0 22.0 27.4 20.4 25.8 33.0 23.2 24.9 26.3 37.7 22.4 18.4 22.0 23.2 12.6 18.2 33.5 18.1 37.7 17.5 12.3 19.2 19.6 73.6 28.8 15.6 19.8 19.9 20.8 19.5 24.8 23.9 21.5 16.7 22.8 17.8 25.4 21.5 21.3 16.3 15.3 24.1 25.5 15.0 35.5 4.9 39.2 47.7 19.1 15.5 32.8 23.6 17.7 28.4 27.7 14.5 28.0 24.8 21.3 14.7 12.4 15.7 21.4 17.8 12.7 11.2 20.5 4.1 3.5 4.7 3.3 4.3 4.4 3.4 4.2 3.7 3.1 3.2 4.1 4.8 4.3 4.2 3.5 5.7 3.6 1.3 8.4 8.3 14.9 11.2 7.5 16.4 7.7 9.8 7.5 6.0 10.7 10.6 37.1 22.4 22.4 82.3 19.5 98.1 57.5 17.9 23.9 27.2 37.1 25.1 51.7 28.6 22.1 31.3 27.1 22.1 17.5 34.1 11.7 38.9 21.8 32.7 48.0 36.0 31.9 43.8 110.9 26.3 19.9 39.6 20.4 46.9 8.8 21.7 35.0 43.1 12.8 37.0 119.0 18.8 16.2 23.9 45.7 13.4 26.8 22.9 44.4 92.8 18.9 24.6 11.3 102.1 139.2 40.3 13.2 27.8 31.3 49.6 13.2 43.3 25.2 30.2 26.3 52.3 51.9 59.8 53.6 31.4 96.5 33.2 21.4 26.1 16.3 53.6 SVIL ENSG00000197321 Supervillin O95425 10 29457338-29736959 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 808.1;tongue: 581.5" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 204.9;Cardiomyocytes: 469.6;Peritubular cells: 260.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 259.3" "Lineage enriched" "Detected in all" 9 "granulocytes: 259.3" "Cell line enhanced" "Detected in many" "HaCaT: 146.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010878, HPA020095, HPA020138" Approved Supported "Plasma membrane,Actin filaments,Cytosol" NA NA 210000 "Cluster 1: Neutrophils - Mixed function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Actin filaments, Cytosol" "CAB010878: AB_476685, HPA020095: AB_1857680, HPA020138: AB_1857681" "unprognostic (1.11e-1)" "unprognostic (2.94e-1)" "unprognostic (8.06e-2)" "unprognostic (1.15e-2)" "unprognostic (3.47e-3)" "unprognostic (2.26e-2)" "unprognostic (4.12e-1)" "unprognostic (1.49e-1)" "unprognostic (4.28e-1)" "unprognostic (3.42e-3)" "unprognostic (1.55e-1)" "unprognostic (9.20e-2)" "unprognostic (2.38e-3)" "unprognostic (7.11e-3)" "unprognostic (1.51e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (5.70e-5)" 26.4 13.4 3.7 22.7 3.9 37.2 22.6 1.3 8.9 45.8 2.5 314.5 14.8 116.2 24.1 92.1 55.5 52.0 165.0 2.2 2.7 15.4 10.4 22.9 12.6 7.0 4.1 83.3 18.5 31.8 8.5 17.9 4.4 70.3 37.1 10.3 40.6 100.0 808.1 26.9 60.1 107.0 4.4 7.6 77.6 11.7 4.9 19.1 35.0 581.5 10.8 173.2 40.3 5.2 71.4 27.9 12.4 5.4 32.1 84.4 22.1 12.6 24.1 4.3 4.7 34.4 63.1 2.4 43.0 4.9 31.9 146.8 8.6 25.6 5.2 1.4 17.6 0.1 33.6 19.9 21.4 8.0 1.5 72.7 24.5 44.2 19.1 71.9 69.6 14.7 0.1 0.4 6.7 19.9 7.7 4.0 7.0 27.8 15.1 15.5 32.1 0.9 40.2 20.1 18.1 14.1 12.3 1.4 34.3 39.8 12.9 7.9 46.3 21.9 23.4 94.4 34.4 0.6 0.8 0.3 64.5 14.0 65.4 43.4 12.1 58.2 11.1 14.0 10.9 0.6 11.2 7.6 7.3 1.0 17.1 10.9 259.3 14.6 29.6 3.0 4.3 3.7 3.7 3.9 1.3 8.9 2.2 2.7 7.0 4.1 4.4 4.4 4.9 5.2 31.3 48.1 30.5 2.3 3.7 70.2 108.0 41.1 204.9 11.7 36.6 67.1 469.6 18.6 53.5 38.6 25.0 29.7 11.3 39.7 7.9 94.1 4.0 26.3 65.8 61.1 23.9 1.7 8.3 42.3 18.5 68.1 7.7 43.6 10.1 35.7 32.2 11.8 10.4 5.0 43.9 31.3 28.5 7.5 45.7 6.8 109.6 25.3 28.4 146.1 16.7 30.6 13.4 28.1 6.6 63.4 40.2 260.7 3.3 131.8 18.4 10.8 42.2 15.0 46.0 90.6 92.9 6.5 11.1 103.8 60.0 24.8 14.6 27.9 39.2 98.3 SYNPO KIAA1029 ENSG00000171992 Synaptopodin Q8N3V7 5 150601080-150659207 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 369.6;skeletal muscle: 1296.3;tongue: 502.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 264.7;Distal enterocytes: 70.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Lineage enriched" "Detected in single" 10 "B-cells: 1.0" "Cell line enhanced" "Detected in many" "BEWO: 88.4;EFO-21: 72.8;HUVEC TERT2: 72.7;TIME: 178.0;U-87 MG: 152.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033265, HPA034631, CAB037325, HPA071347" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "Actin filaments" "CAB033265: AB_2201163, CAB037325: , HPA034631: AB_10669994, HPA071347: AB_2732179" "unprognostic (2.09e-2)" "unprognostic (7.72e-3)" "unprognostic (3.95e-2)" "unprognostic (2.78e-3)" "unprognostic (3.07e-2)" "unprognostic (1.66e-2)" "unprognostic (1.76e-1)" "unprognostic (1.41e-2)" "unprognostic (1.90e-1)" "unprognostic (1.21e-1)" "unprognostic (1.17e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (1.53e-6)" "unprognostic (1.23e-1)" "unprognostic (5.72e-2)" "unprognostic (2.21e-2)" "unprognostic (6.35e-2)" 91.8 112.1 103.5 21.3 60.7 0.3 48.6 0.0 88.9 23.2 0.8 37.4 31.4 38.7 20.9 31.0 30.8 32.2 369.6 91.2 5.2 60.6 38.5 72.1 10.6 18.2 8.5 34.6 32.9 17.1 21.6 23.8 5.2 46.0 17.5 10.0 21.6 29.1 1296.3 15.4 39.6 38.9 20.6 38.9 34.9 17.0 5.1 6.6 31.1 502.1 11.1 56.8 22.3 34.9 0.5 24.2 0.2 0.3 3.5 3.2 88.4 13.8 18.9 4.6 3.7 21.6 9.7 0.1 72.8 19.9 29.2 8.9 0.1 13.5 1.9 0.2 0.2 0.0 37.4 4.7 19.6 0.0 0.9 3.7 21.3 5.2 3.7 27.5 72.7 0.2 0.2 0.2 4.4 1.6 0.1 0.7 2.8 9.3 11.6 0.5 0.7 0.2 3.4 1.9 8.5 39.3 19.9 21.6 0.7 31.1 1.6 6.6 178.0 17.4 53.2 0.4 3.6 0.8 0.2 1.3 152.5 0.3 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 103.5 60.7 0.0 88.9 91.2 5.2 18.2 8.5 5.2 20.6 5.1 34.9 51.1 35.3 12.2 1.3 4.8 4.6 3.0 32.6 1.8 1.9 6.4 2.5 264.7 27.1 17.0 7.3 2.1 14.8 0.5 70.5 0.0 43.7 1.7 0.4 0.4 56.3 13.8 2.7 22.5 34.5 6.0 19.9 4.6 0.5 0.0 40.9 62.8 40.0 2.1 0.0 5.7 8.4 2.0 10.8 5.1 3.4 2.8 0.9 5.4 6.5 24.0 7.2 0.0 2.5 1.3 35.6 24.4 27.8 0.6 5.7 52.6 4.4 7.6 0.8 46.0 18.0 29.2 1.2 0.8 1.4 2.3 25.9 1.6 8.6 11.8 3.6 SZT2 "C1orf84, FLJ10387, FLJ34502, KIAA0467, RP11-506B15.1, SZT2A, SZT2B" ENSG00000198198 "SZT2 subunit of KICSTOR complex" Q5T011 1 43389882-43454247 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 62.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029012 Approved Approved "Nucleoplasm,Vesicles,Actin filaments" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 20: HeLa - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Vesicles, Actin filaments" "HPA029012: AB_10600817" "unprognostic (1.35e-1)" "unprognostic (2.55e-1)" "unprognostic (4.14e-1)" "unprognostic (6.61e-2)" "unprognostic (1.29e-1)" "prognostic favorable (1.47e-7)" "prognostic unfavorable (2.53e-4)" "prognostic favorable (6.20e-4)" "unprognostic (1.54e-1)" "unprognostic (1.81e-2)" "unprognostic (5.96e-2)" "unprognostic (1.03e-1)" "unprognostic (1.05e-2)" "unprognostic (1.84e-3)" "unprognostic (8.28e-2)" "unprognostic (7.19e-2)" "unprognostic (2.61e-2)" 6.3 5.3 1.3 4.3 2.5 6.0 6.2 3.2 3.1 6.1 0.8 6.7 3.4 7.2 2.6 5.9 7.0 2.7 5.4 1.1 2.1 4.7 4.4 6.4 4.2 2.9 2.3 8.0 6.5 5.6 8.8 2.7 2.5 6.5 3.4 4.0 6.5 3.2 6.6 7.7 7.9 3.6 0.9 7.1 6.4 9.6 3.0 4.4 9.0 3.9 4.1 6.2 5.8 5.0 4.5 4.4 3.7 3.4 9.1 4.5 5.7 3.7 4.4 4.5 4.1 1.5 5.0 4.1 4.1 5.9 3.2 5.1 3.7 6.3 3.9 5.1 3.4 7.5 8.1 2.7 3.4 6.1 6.2 4.8 4.2 7.7 7.5 5.0 5.2 4.7 3.4 6.8 3.2 2.1 4.1 1.6 3.3 2.7 4.5 4.5 5.1 4.9 2.6 6.2 3.8 3.4 7.8 5.9 4.0 4.8 3.2 8.8 6.5 4.8 6.8 6.4 6.5 7.3 2.8 3.4 4.9 3.8 3.1 1.4 0.5 1.4 0.3 0.4 0.8 0.3 0.1 0.1 0.4 0.3 0.4 0.3 1.1 0.3 0.5 0.9 0.4 0.2 1.3 2.5 3.2 3.1 1.1 2.1 2.9 2.3 2.5 0.9 3.0 5.0 8.3 25.6 19.3 19.6 10.5 1.9 3.5 5.1 6.2 16.8 7.7 7.0 4.8 5.7 6.8 5.5 62.6 6.5 9.2 10.0 0.0 6.1 14.2 5.8 10.1 7.6 3.6 5.5 20.4 6.4 5.2 7.0 13.7 6.9 14.5 19.0 12.8 13.1 5.4 13.5 20.2 7.0 4.1 7.0 3.1 15.8 9.3 9.4 5.4 15.9 11.6 5.8 13.4 11.1 29.1 6.8 3.7 6.0 9.5 4.2 10.5 9.2 8.0 22.2 19.7 9.1 7.1 8.1 8.6 4.2 1.8 5.5 11.4 12.6 7.0 3.8 TAS2R10 "T2R10, TRB2" ENSG00000121318 "Taste 2 receptor member 10" Q9NYW0 12 10825317-10826358 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Astrocytes: 6.2;Excitatory neurons: 14.4;Inhibitory neurons: 14.4;Microglial cells: 4.7;Oligodendrocyte precursor cells: 14.1;Oligodendrocytes: 11.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA070201 Approved "Vesicles,Plasma membrane,Actin filaments" NA NA "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Plasma membrane" "Actin filaments" "HPA070201: " "unprognostic (1.28e-1)" "unprognostic (3.89e-4)" "unprognostic (1.77e-1)" "unprognostic (1.82e-2)" "unprognostic (1.10e-1)" "unprognostic (5.82e-3)" "unprognostic (3.86e-1)" "unprognostic (7.72e-2)" "unprognostic (5.27e-2)" "unprognostic (1.67e-1)" "unprognostic (1.24e-2)" "unprognostic (1.20e-1)" "unprognostic (4.16e-5)" "unprognostic (5.41e-2)" "unprognostic (3.18e-2)" "unprognostic (2.87e-2)" "unprognostic (2.56e-3)" 0.2 0.6 0.1 0.0 0.1 0.0 0.2 0.1 0.4 0.3 0.0 0.2 0.0 0.4 0.1 0.1 0.1 0.0 0.2 0.1 0.0 0.2 0.3 0.2 0.0 0.1 0.1 0.3 0.2 0.0 0.4 0.0 0.1 0.2 0.0 0.3 0.4 0.0 0.0 0.1 0.3 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.0 0.0 0.0 6.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 14.4 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.7 0.0 0.1 0.0 14.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 14.1 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 TAS2R42 "hT2R55, T2R24, T2R55, TAS2R55" ENSG00000186136 "Taste 2 receptor member 42" Q7RTR8 12 11185993-11186937 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA036149 Uncertain Approved "Nucleoplasm,Actin filaments,Focal adhesion sites" NA NA "Nucleoplasm, Actin filaments" "Focal adhesion sites" "HPA036149: AB_10672080" "unprognostic (2.45e-2)" "unprognostic (4.17e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TAX1BP3 TIP-1 ENSG00000213977 "Tax1 binding protein 3" O14907 17 3662895-3668679 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 395.9;Ductal cells: 351.0;Exocrine glandular cells: 385.9;Pancreatic endocrine cells: 505.8;Paneth cells: 362.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 164.3;granulocytes: 217.8;monocytes: 78.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046410, HPA063078" Approved Approved "Nucleoli fibrillar center,Vesicles,Actin filaments" NA NA 120000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli fibrillar center" "Vesicles, Actin filaments" "HPA046410: AB_2679656, HPA063078: AB_2684937" "unprognostic (6.15e-2)" "unprognostic (6.46e-3)" "unprognostic (3.37e-1)" "unprognostic (1.32e-1)" "prognostic unfavorable (2.17e-4)" "unprognostic (1.68e-1)" "unprognostic (1.12e-3)" "prognostic unfavorable (1.76e-4)" "unprognostic (1.80e-2)" "unprognostic (5.45e-3)" "unprognostic (5.19e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (7.90e-4)" "unprognostic (5.12e-2)" "unprognostic (2.10e-1)" "unprognostic (2.10e-3)" "unprognostic (1.92e-1)" 107.3 131.8 62.7 49.2 78.5 16.5 94.4 67.9 67.3 192.9 48.2 108.5 108.8 128.1 33.6 258.5 84.4 90.9 194.8 57.3 58.8 115.0 39.7 94.9 39.3 72.5 73.3 95.9 80.4 23.5 30.9 53.2 69.9 91.7 77.4 3.7 109.7 105.6 28.7 120.4 119.6 70.3 66.2 52.3 136.5 51.2 65.2 44.6 63.6 33.4 49.0 102.8 160.1 80.6 183.1 319.1 68.4 38.5 219.2 175.6 81.3 223.6 184.5 234.0 136.7 135.9 144.5 19.1 159.1 290.8 77.2 282.6 39.1 205.3 90.8 50.7 64.4 25.9 75.8 106.6 191.1 4.3 37.7 267.6 322.5 145.1 68.9 165.3 266.0 50.1 9.6 14.4 280.1 169.4 52.2 15.1 65.9 116.7 112.6 50.0 41.8 16.3 248.6 141.2 14.7 43.2 276.2 116.2 39.4 67.5 125.3 23.2 269.6 195.3 75.2 154.9 230.2 5.7 2.6 5.5 117.4 30.0 190.3 217.8 65.4 120.4 26.9 78.9 22.2 29.2 25.0 26.6 58.7 25.3 17.3 22.7 73.8 20.0 73.6 164.3 36.7 53.3 62.7 78.5 67.9 67.3 57.3 58.8 72.5 73.3 69.9 66.2 65.2 80.6 51.5 60.9 25.8 0.0 19.0 95.3 79.7 229.3 99.6 1.6 51.0 28.2 41.5 92.9 107.6 99.3 0.0 124.7 68.5 395.9 88.0 351.0 16.2 12.8 27.3 77.0 24.6 21.4 0.0 385.9 145.3 72.6 43.8 16.1 26.6 21.2 75.3 11.1 69.8 5.0 0.0 120.0 71.2 35.2 73.2 10.5 174.6 64.0 113.8 0.0 85.5 19.8 26.8 0.0 0.0 505.8 362.8 209.9 5.8 89.0 279.2 185.3 26.8 2.6 39.5 44.1 78.6 8.6 12.8 94.5 76.0 155.6 16.1 92.0 103.0 107.9 TIGD6 DKFZp761E2110 ENSG00000164296 "Tigger transposable element derived 6" Q17RP2 5 149993118-150000654 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 20.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA044599 Uncertain Approved "Nucleoplasm,Vesicles,Actin filaments" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Vesicles, Actin filaments" "HPA044599: AB_10961286" "unprognostic (1.06e-1)" "unprognostic (3.25e-1)" "prognostic favorable (5.35e-4)" "unprognostic (1.94e-2)" "unprognostic (8.18e-2)" "unprognostic (3.00e-2)" "unprognostic (1.30e-3)" "unprognostic (7.48e-2)" "unprognostic (5.96e-2)" "unprognostic (3.85e-2)" "prognostic favorable (5.88e-4)" "unprognostic (1.94e-3)" "unprognostic (1.85e-3)" "unprognostic (1.55e-2)" "unprognostic (1.46e-1)" "unprognostic (1.33e-3)" "unprognostic (1.18e-1)" 2.6 3.6 2.1 1.7 2.4 1.3 4.7 2.7 2.4 2.5 2.6 2.8 2.2 2.4 5.1 1.7 3.1 2.3 2.0 2.0 2.3 3.6 2.8 2.4 1.9 2.2 2.3 3.9 3.2 11.2 2.6 2.6 2.2 4.1 2.5 3.5 3.1 3.0 1.4 2.7 2.0 2.6 2.1 2.1 2.9 4.0 2.2 2.3 3.0 2.2 2.0 2.4 1.7 2.5 2.1 5.7 3.8 8.2 10.7 8.8 5.9 6.0 6.3 4.6 4.6 3.7 3.7 1.0 5.3 7.1 5.7 3.7 3.4 4.4 5.4 4.7 2.8 1.8 3.1 2.0 9.5 2.6 4.4 9.0 8.3 5.9 7.7 5.4 3.6 4.1 2.5 4.7 5.8 5.0 3.4 1.2 1.5 2.7 4.8 3.9 4.3 2.7 4.4 3.0 2.9 3.8 4.2 6.7 9.1 4.6 7.5 4.5 4.9 3.7 2.8 4.1 4.5 3.5 1.4 2.7 5.9 2.8 5.9 0.0 2.2 1.2 1.5 2.3 1.3 1.4 2.0 1.5 1.9 1.7 4.2 2.6 0.0 3.4 1.3 1.0 2.2 1.5 2.1 2.4 2.7 2.4 2.0 2.3 2.2 2.3 2.2 2.1 2.2 2.5 3.1 12.8 2.7 1.3 2.2 2.2 6.6 2.9 2.2 6.2 5.4 3.7 5.4 4.3 4.7 3.7 0.0 5.2 2.6 2.0 7.9 5.1 1.2 2.9 3.5 2.7 3.0 0.4 1.4 4.7 2.7 3.5 7.1 3.6 3.8 4.6 3.3 1.8 4.2 3.3 1.6 2.6 6.1 1.9 1.9 2.1 4.4 2.6 3.6 2.8 4.8 6.3 1.0 4.5 5.6 4.3 1.9 3.4 3.8 5.7 3.1 7.9 3.6 6.3 0.0 2.1 3.8 20.0 8.7 2.6 1.1 3.6 2.2 6.8 2.0 4.9 TMEM50A SMP1 ENSG00000183726 "Transmembrane protein 50A" O95807 1 25338317-25362361 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065192 Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "Actin filaments, Cytosol" "HPA065192: AB_2685429" "unprognostic (2.41e-2)" "unprognostic (2.74e-1)" "unprognostic (5.17e-3)" "prognostic favorable (8.64e-5)" "unprognostic (1.45e-1)" "unprognostic (2.04e-2)" "prognostic unfavorable (3.34e-4)" "unprognostic (7.39e-2)" "unprognostic (7.92e-3)" "unprognostic (2.53e-1)" "unprognostic (1.02e-2)" "unprognostic (2.44e-2)" "unprognostic (2.39e-3)" "unprognostic (6.66e-2)" "unprognostic (2.91e-1)" "unprognostic (3.91e-3)" "unprognostic (3.44e-2)" 47.2 63.0 43.9 44.5 47.8 41.8 55.5 45.3 55.8 47.0 43.7 58.5 49.6 35.7 53.0 36.5 38.4 45.7 44.2 45.0 44.4 55.0 33.4 58.1 52.2 46.5 44.4 26.2 32.6 49.5 14.6 57.7 46.4 54.4 65.7 45.4 81.5 52.7 16.9 41.1 55.4 46.0 47.2 46.9 49.5 16.1 45.5 47.1 47.0 26.5 47.3 55.1 29.8 50.4 43.3 44.6 74.3 42.3 132.9 119.8 28.1 89.0 123.6 143.4 159.5 36.5 110.9 50.2 47.9 274.6 55.7 62.6 56.3 61.9 161.2 126.1 81.4 104.7 47.5 55.2 96.5 82.4 80.3 128.0 91.4 106.1 60.5 69.7 107.0 50.8 73.1 79.5 140.9 30.6 53.2 90.2 90.6 73.7 37.1 45.7 85.3 88.9 148.8 30.9 64.5 42.3 89.0 64.2 72.2 69.3 32.7 52.0 171.0 86.5 36.6 144.9 36.8 52.3 61.5 45.0 117.1 117.2 50.3 275.5 76.9 109.8 87.9 94.7 91.9 49.6 77.2 91.1 55.9 40.9 55.1 76.6 159.2 80.5 117.3 51.9 95.4 106.3 43.9 47.8 45.3 55.8 45.0 44.4 46.5 44.4 46.4 47.2 45.5 50.4 244.8 144.2 84.2 21.2 107.9 253.4 184.5 392.3 146.8 43.9 162.0 164.8 105.6 102.9 212.7 169.2 27.1 108.9 191.0 175.6 50.9 300.3 25.4 136.4 119.3 203.3 83.0 93.6 31.6 215.6 312.5 198.1 91.3 180.8 126.6 58.2 152.0 68.3 227.1 25.2 27.3 170.7 309.3 162.4 245.1 12.7 151.9 223.8 199.3 16.9 253.8 102.0 154.5 28.1 48.8 315.3 164.8 98.9 168.2 340.6 120.0 113.1 205.1 41.7 210.4 71.6 200.6 94.7 47.0 166.8 317.7 181.6 180.9 116.9 106.9 274.3 TNNC1 TNNC ENSG00000114854 "Troponin C1, slow skeletal and cardiac type" P63316 3 52451100-52454041 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Cardiomyopathy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 36 "heart muscle: 8734.3;skeletal muscle: 21081.1;tongue: 12403.9" "Cell type enriched" "Detected in many" 10 "Cardiomyocytes: 3550.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 27.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.2" "Lineage enriched" "Detected in single" 6 "T-cells: 1.2" "Cell line enhanced" "Detected in many" "CACO-2: 68.2;CAPAN-2: 33.5;EFO-21: 65.2;HeLa: 49.1;Hep G2: 46.1;HSkMC: 67.2;U-2 OS: 97.7" "Region enriched" "Detected in all" 4 "cerebral cortex: 87.0" "Group enriched" "Detected in some" 6 "midbrain: 7.6;spinal cord: 7.1" "CAB002450, HPA044848, HPA056897" Enhanced Approved "Nucleoplasm,Actin filaments,Mitochondria" NA NA 990000 "Cluster 13: T-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 9: U-2 OS - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Actin filaments, Mitochondria" "CAB002450: AB_564152, HPA044848: AB_2679110, HPA056897: AB_2683269" "unprognostic (2.18e-2)" "unprognostic (1.70e-1)" "unprognostic (8.66e-2)" "unprognostic (3.43e-1)" "unprognostic (4.00e-2)" "unprognostic (1.88e-2)" "unprognostic (1.11e-1)" "unprognostic (1.43e-1)" "unprognostic (1.53e-1)" "unprognostic (3.92e-1)" "unprognostic (1.03e-1)" "unprognostic (1.07e-1)" "unprognostic (2.15e-2)" "unprognostic (4.95e-2)" "unprognostic (2.31e-1)" "unprognostic (4.15e-2)" "unprognostic (4.86e-1)" 8.4 10.9 0.7 0.8 0.8 0.7 19.1 2.7 1.1 7.7 7.3 4.0 1.1 2.8 41.7 387.3 2.8 3.3 8734.3 1.2 0.7 19.2 4.0 78.5 3.9 0.8 0.9 2.4 6.8 1.6 17.6 5.2 1.0 170.1 4.1 0.4 120.8 2.2 21081.1 18.9 3.3 0.8 0.8 2.8 5.7 10.6 0.8 4.3 14.4 12403.9 1.6 5.3 5.4 0.7 0.7 5.2 3.6 0.6 0.2 0.5 8.0 0.4 0.3 0.3 0.4 68.2 33.5 0.5 65.2 9.9 0.1 0.4 0.1 0.3 0.0 1.2 1.6 0.5 49.1 46.1 0.3 0.3 0.1 67.2 1.2 0.0 0.7 0.6 0.0 2.0 0.2 5.1 2.0 0.1 0.2 0.8 0.5 15.1 0.7 0.1 2.9 2.3 3.3 13.0 0.2 0.0 0.5 6.7 0.1 3.9 26.7 0.5 0.0 0.1 97.7 0.8 0.2 2.8 1.3 0.9 0.3 0.7 0.1 0.0 0.0 0.0 0.2 0.0 1.2 0.0 0.2 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.8 0.1 0.7 0.8 2.7 1.1 1.2 0.7 0.8 0.9 1.0 0.8 0.8 0.7 0.2 125.0 12.6 0.0 0.3 1.5 1.7 4.0 0.6 0.2 0.5 0.3 3550.1 5.7 7.9 3.7 2.1 59.0 0.1 1.6 27.4 11.8 0.7 66.4 6.7 39.8 330.7 0.4 0.0 13.0 5.1 52.7 0.5 98.8 0.0 0.8 0.7 0.7 4.9 0.0 0.0 1.7 2.0 0.0 1.4 5.8 22.4 2.6 5.4 0.0 0.1 1.2 0.0 0.0 0.0 6.5 0.3 177.6 0.1 0.8 0.5 1.3 2.8 0.1 0.0 241.8 36.0 2.1 1.0 0.1 0.9 31.1 2.8 1.3 2.0 6.8 TRIM71 "LIN-41, LIN41" ENSG00000206557 "Tripartite motif containing 71" Q2Q1W2 3 32817997-32897824 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "RNA-mediated gene silencing, Ubl conjugation pathway" "Developmental protein, RNA-binding, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 4.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Extravillous trophoblasts: 15.6;Inhibitory neurons: 4.5;Oligodendrocyte precursor cells: 4.5;Spermatogonia: 13.7" "Cancer enriched" "Detected in some" 28 "testis cancer: 28.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 31.4;BEWO: 94.5;Hep G2: 63.8;NTERA-2: 84.3;SuSa: 76.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA038141, HPA038142" Uncertain Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 5: NTERA-2 - Transcription" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Actin filaments, Focal adhesion sites" "HPA038141: AB_2675857, HPA038142: AB_10697240" "unprognostic (2.93e-2)" "unprognostic (4.29e-3)" "unprognostic (1.70e-1)" "unprognostic (1.02e-2)" "unprognostic (2.58e-2)" "unprognostic (3.27e-2)" "unprognostic (2.09e-2)" "unprognostic (1.25e-1)" "unprognostic (3.16e-2)" "unprognostic (3.04e-1)" "unprognostic (1.11e-2)" "unprognostic (3.11e-1)" "unprognostic (4.36e-6)" "unprognostic (3.92e-2)" "unprognostic (9.27e-2)" "unprognostic (8.17e-2)" "unprognostic (4.65e-2)" 0.0 0.0 1.0 0.0 1.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.8 0.9 0.0 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 31.4 0.0 0.0 0.0 94.5 0.0 0.0 0.0 0.0 23.1 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 1.6 0.0 63.8 0.0 1.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.4 0.0 0.0 0.6 6.9 84.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 76.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 0.8 0.9 0.8 0.1 0.1 0.1 0.0 0.8 0.2 0.0 9.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.1 0.0 2.7 0.0 1.8 0.0 0.0 3.9 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.2 0.0 0.0 3.1 0.0 15.6 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 4.5 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 1.0 0.1 0.0 0.0 4.5 0.1 0.0 0.0 0.4 0.0 0.0 0.0 3.6 0.7 0.5 0.0 0.0 0.1 0.3 13.7 0.0 0.0 4.0 0.1 0.0 0.0 0.0 UQCC1 "BFZB, C20orf44, CBP3, FLJ10850, UQCC" ENSG00000101019 "Ubiquinol-cytochrome c reductase complex assembly factor 1" Q9NVA1 20 35302566-35412031 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 106.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 64.6;Inhibitory neurons: 68.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034875 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nucleoplasm, Actin filaments" "HPA034875: AB_10603226" "unprognostic (9.66e-2)" "unprognostic (3.93e-1)" "unprognostic (3.45e-1)" "unprognostic (8.72e-3)" "unprognostic (4.01e-1)" "unprognostic (1.31e-1)" "unprognostic (5.73e-2)" "unprognostic (2.75e-1)" "unprognostic (2.82e-2)" "unprognostic (7.66e-2)" "unprognostic (3.42e-2)" "unprognostic (7.01e-2)" "unprognostic (6.72e-3)" "unprognostic (3.23e-1)" "unprognostic (3.60e-1)" "unprognostic (5.27e-2)" "unprognostic (1.34e-2)" 19.4 30.0 22.0 13.8 24.3 4.6 16.5 21.9 27.7 20.1 20.9 26.0 18.9 18.6 22.9 18.8 20.6 12.6 55.3 22.4 23.0 28.6 27.1 15.8 17.9 24.1 23.5 19.8 15.9 37.2 23.9 14.9 26.6 19.7 25.8 29.5 18.7 18.4 106.8 16.3 19.3 18.5 19.9 19.7 23.0 17.6 22.9 21.2 22.3 105.7 21.9 20.1 18.0 22.8 20.2 28.6 33.5 32.2 34.1 38.4 4.8 38.5 43.3 70.7 48.1 97.7 39.4 66.6 68.5 26.1 60.7 53.5 60.0 70.0 52.6 19.0 24.2 89.2 41.3 80.3 22.7 54.2 25.6 37.6 72.3 37.9 48.8 51.2 24.6 53.5 39.9 23.9 50.0 26.8 58.6 29.2 25.4 42.0 61.5 31.4 50.0 37.9 67.6 26.2 46.4 28.7 32.9 148.9 34.0 28.1 23.9 34.6 23.5 46.2 28.8 25.9 34.6 30.1 37.2 26.5 79.7 31.1 36.8 28.6 10.2 14.2 14.8 14.3 18.3 12.3 13.7 14.7 16.0 15.7 16.7 14.7 0.3 22.3 10.2 14.4 14.2 12.6 22.0 24.3 21.9 27.7 22.4 23.0 24.1 23.5 26.6 19.9 22.9 22.8 7.0 0.0 7.8 51.6 7.0 6.4 9.3 18.1 6.8 20.7 7.8 5.8 44.0 10.0 11.8 16.5 8.4 22.9 5.3 13.9 60.7 18.2 15.1 10.5 8.5 10.5 12.0 5.2 64.6 13.1 15.7 9.2 7.7 6.9 8.2 17.5 6.1 14.2 11.6 18.5 68.9 9.1 18.3 6.6 3.9 8.6 10.5 5.8 14.2 33.7 13.2 16.7 10.3 44.2 50.3 19.1 6.6 12.0 5.0 8.4 10.9 19.4 14.8 22.8 6.6 9.6 11.9 24.6 18.2 6.2 5.3 17.4 6.2 19.7 13.2 9.6 XIRP1 "CMYA1, DKFZp451D042, Xin" ENSG00000168334 "Xin actin binding repeat containing 1" Q702N8 3 39183210-39192596 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 682.0;skeletal muscle: 383.4" "Cell type enriched" "Detected in some" 15 "Cardiomyocytes: 850.5" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.0" "Region enhanced" "Detected in some" "cerebellum: 2.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 4.4;LHCN-M2: 1.1;RH-30: 3.0" "Not detected" "Not detected" "HPA016750, HPA018458, CAB026391" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Actin filaments" Nucleoplasm "CAB026391: , HPA016750: AB_1858884, HPA018458: AB_1858885" "unprognostic (2.19e-1)" "unprognostic (6.40e-2)" "unprognostic (1.13e-1)" "unprognostic (9.75e-2)" "unprognostic (2.76e-1)" "unprognostic (2.43e-2)" "unprognostic (4.94e-2)" "unprognostic (2.66e-3)" "unprognostic (1.66e-3)" "unprognostic (1.46e-1)" "unprognostic (5.30e-2)" "unprognostic (6.26e-2)" "unprognostic (1.02e-5)" "unprognostic (2.08e-2)" "unprognostic (2.78e-2)" "unprognostic (6.86e-4)" "unprognostic (4.12e-2)" 1.1 0.3 0.0 1.2 0.0 0.0 0.2 2.0 0.3 0.0 0.1 0.7 0.0 0.2 0.0 5.6 0.0 1.0 682.0 1.1 0.1 0.1 0.1 1.7 0.0 0.6 0.2 0.1 1.2 0.0 0.5 0.7 0.2 3.4 0.0 0.0 5.1 0.0 383.4 0.5 0.5 0.4 0.2 0.6 0.3 0.0 0.1 0.5 0.2 96.4 0.0 3.5 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.3 1.1 0.1 0.6 0.2 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 850.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.2 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.4 3.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 ZSCAN22 "HKR2, ZNF50" ENSG00000182318 "Zinc finger and SCAN domain containing 22" P10073 19 58326994-58342332 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEK 293: 14.7" "Low region specificity" "Detected in all" HPA006471 Uncertain Uncertain "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 15: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Cytosol" "Actin filaments" "HPA006471: AB_2221026" "unprognostic (5.55e-3)" "unprognostic (2.24e-1)" "unprognostic (6.56e-2)" "unprognostic (1.13e-1)" "unprognostic (1.93e-1)" "unprognostic (3.82e-2)" "unprognostic (2.47e-3)" "unprognostic (1.52e-1)" "unprognostic (2.91e-1)" "unprognostic (1.15e-1)" "unprognostic (2.15e-3)" "unprognostic (5.00e-2)" "unprognostic (7.59e-2)" "unprognostic (2.59e-2)" "unprognostic (1.74e-1)" "unprognostic (5.22e-3)" "unprognostic (1.07e-1)" 1.2 1.5 1.4 1.3 1.7 0.7 1.1 2.9 1.6 1.7 1.0 1.5 1.2 1.5 0.8 1.8 1.3 0.7 1.2 1.3 1.4 1.3 2.4 1.1 1.2 1.4 1.2 1.5 1.4 1.6 2.6 1.2 1.4 1.4 0.9 0.8 1.2 1.0 1.1 2.3 1.3 1.2 0.8 1.4 1.4 1.2 1.2 1.1 1.3 1.0 1.4 1.5 1.5 2.8 2.4 4.2 2.3 3.5 2.6 1.6 2.4 2.0 1.0 1.2 1.1 2.3 1.7 1.9 1.3 1.6 1.5 1.8 3.3 2.2 1.3 3.0 14.7 4.1 4.2 2.1 2.1 3.3 4.2 1.8 2.2 2.6 2.7 2.2 1.8 1.9 4.1 3.6 2.1 1.9 1.6 1.5 2.0 3.0 4.8 2.2 3.6 3.3 1.2 3.1 3.6 2.6 3.0 4.0 2.0 1.8 1.9 2.3 1.8 6.5 1.9 1.6 3.5 3.6 5.3 1.4 2.6 2.2 2.3 0.0 0.8 1.0 2.0 0.7 1.3 0.8 1.1 1.6 1.1 1.0 0.9 1.0 0.2 1.2 0.9 0.5 0.9 1.0 1.4 1.7 2.9 1.6 1.3 1.4 1.4 1.2 1.4 0.8 1.2 2.8 1.1 0.0 4.1 1.6 1.5 1.8 0.6 1.0 0.0 0.7 1.3 0.9 0.6 1.5 1.6 1.8 0.0 0.9 0.8 0.4 1.9 0.9 0.3 1.1 1.2 0.9 0.0 1.7 2.1 0.6 0.9 1.1 1.1 1.6 0.0 1.1 0.0 1.3 0.5 1.7 2.1 0.5 0.0 0.8 0.8 0.0 2.1 2.3 1.8 0.0 1.3 0.5 0.0 1.0 2.2 1.1 1.6 0.4 1.1 0.9 0.8 0.6 1.1 0.7 0.0 1.7 0.8 4.3 1.9 1.1 3.7 0.7 1.2 0.9 1.0 0.4 ZSCAN29 "FLJ35867, Zfp690, ZNF690" ENSG00000140265 "Zinc finger and SCAN domain containing 29" Q8IWY8 15 43358172-43371025 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 81.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007241, HPA011109" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 16: U-266 - Nucleosome" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane, Actin filaments" "HPA007241: AB_10600420, HPA011109: AB_10611525" "unprognostic (3.90e-2)" "unprognostic (2.70e-1)" "unprognostic (1.15e-1)" "unprognostic (4.06e-2)" "unprognostic (2.21e-2)" "unprognostic (2.02e-2)" "unprognostic (1.57e-1)" "unprognostic (5.25e-1)" "unprognostic (2.12e-2)" "unprognostic (4.77e-3)" "unprognostic (1.64e-1)" "unprognostic (1.44e-3)" "unprognostic (9.61e-2)" "unprognostic (1.30e-1)" "unprognostic (1.31e-1)" "unprognostic (8.33e-2)" "unprognostic (3.43e-2)" 6.3 5.6 7.9 8.6 10.1 5.6 6.8 8.1 7.4 7.2 8.1 7.6 8.8 8.9 5.2 7.2 6.4 6.0 5.5 6.6 7.4 5.7 6.9 6.9 10.7 9.3 9.7 7.4 11.4 7.7 5.5 8.1 8.9 6.8 7.6 13.6 8.5 6.5 9.7 5.8 9.9 6.4 7.7 9.0 8.8 17.3 8.5 10.7 7.2 8.5 10.4 6.6 6.0 10.3 11.7 12.5 28.9 17.9 10.0 10.5 15.6 9.0 13.9 15.6 16.2 19.7 8.1 11.4 14.7 11.1 12.6 33.7 21.5 11.0 13.9 29.6 11.8 25.1 20.5 15.5 11.1 17.3 21.2 9.3 19.0 10.6 14.9 11.0 8.0 17.3 23.7 13.5 12.7 7.4 16.7 14.2 14.5 17.1 9.6 25.7 16.1 14.0 9.1 13.9 20.6 22.2 13.9 22.5 10.4 14.5 15.8 26.6 9.1 18.3 14.4 14.0 16.4 25.8 38.4 21.6 10.7 16.9 14.1 0.4 0.3 3.1 0.4 0.4 0.3 0.8 0.4 0.3 0.4 0.5 0.2 0.6 0.7 1.0 0.3 0.3 0.8 0.3 7.9 10.1 8.1 7.4 6.6 7.4 9.3 9.7 8.9 7.7 8.5 10.3 3.5 6.4 7.9 6.8 5.8 3.6 2.6 3.7 4.6 10.8 4.8 4.8 7.8 4.3 7.8 7.3 27.1 5.1 7.1 11.0 0.0 5.4 81.7 5.0 8.2 4.9 6.1 1.3 6.4 7.1 4.4 5.8 9.7 7.8 0.0 6.5 3.9 7.2 5.8 13.5 5.2 8.1 4.1 10.6 3.7 20.7 6.8 4.8 5.4 9.4 6.7 5.5 10.3 10.1 10.2 8.7 5.0 6.0 3.3 3.9 7.7 2.6 5.2 18.0 0.0 4.9 3.8 12.0 6.7 4.4 3.1 3.8 4.2 2.8 7.0 2.4 ZYX ENSG00000159840 Zyxin Q15942 7 143381295-143391111 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 596.6" "Cell type enhanced" "Detected in many" "Macrophages: 207.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 163.3" "Group enriched" "Detected in all" 4 "dendritic cells: 58.4;granulocytes: 163.3;monocytes: 83.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004835, CAB009321, HPA073497, CAB075747" Enhanced Supported "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 180000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "Focal adhesion sites" "Plasma membrane, Actin filaments" "CAB009321: AB_2221290, CAB075747: AB_2665753, HPA004835: AB_1080771, HPA073497: AB_2686611" "unprognostic (1.96e-2)" "unprognostic (5.35e-2)" "unprognostic (2.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.44e-2)" "unprognostic (1.18e-1)" "unprognostic (2.21e-3)" "unprognostic (1.66e-3)" "unprognostic (2.60e-1)" "unprognostic (4.22e-1)" "unprognostic (1.98e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (7.92e-5)" "unprognostic (1.39e-1)" "unprognostic (8.12e-2)" "unprognostic (1.95e-1)" "unprognostic (6.72e-2)" 211.5 75.4 21.6 82.5 24.3 106.3 191.0 24.4 33.5 275.7 24.8 382.6 28.1 596.6 16.5 136.7 294.9 57.0 152.0 21.9 21.9 99.4 89.9 316.8 53.9 27.5 24.7 168.7 78.5 84.3 52.4 38.4 27.5 171.9 20.2 5.2 108.1 75.3 113.3 130.7 148.7 127.7 23.8 213.6 154.0 98.9 28.8 27.6 89.0 19.1 31.1 301.6 185.9 26.8 73.9 39.3 50.6 70.5 93.9 208.2 63.4 152.1 158.9 146.5 122.7 135.4 42.6 4.6 57.5 168.5 84.1 55.8 31.7 138.0 67.8 81.6 18.7 105.9 45.7 46.9 163.8 86.4 162.6 222.9 60.5 160.1 54.0 90.5 187.9 9.1 28.0 42.8 159.6 73.4 1.3 165.9 110.0 25.4 273.1 16.3 28.0 6.4 112.2 34.6 2.8 39.5 112.3 99.2 57.0 45.9 12.1 80.5 343.7 176.5 74.1 187.9 152.4 15.6 20.4 11.7 154.6 87.4 119.8 18.9 70.8 48.2 20.2 70.4 16.2 3.1 19.4 23.3 58.4 2.0 11.7 13.8 163.3 14.7 83.6 14.5 19.1 44.1 21.6 24.3 24.4 33.5 21.9 21.9 27.5 24.7 27.5 23.8 28.8 26.8 51.6 6.4 6.4 8.1 26.7 33.8 174.0 78.4 26.7 3.7 40.2 85.3 11.6 25.8 45.4 35.0 0.0 40.6 51.7 40.1 7.9 100.3 1.5 23.4 172.6 58.2 38.2 19.3 36.9 94.1 95.8 66.6 44.9 42.0 36.8 13.7 55.3 32.0 164.6 0.0 18.3 26.7 24.4 195.7 95.1 6.8 28.6 207.1 14.2 7.5 171.9 15.1 40.2 7.5 5.2 169.8 48.2 55.3 20.3 61.3 19.8 19.6 9.9 3.0 85.5 48.7 103.9 7.3 9.9 46.3 20.2 28.0 91.9 8.8 28.6 106.4