Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ACACA "ACAC, ACC, ACC1" ENSG00000278540 "Acetyl-CoA carboxylase alpha" Q13085 17 37084992-37406836 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Allosteric enzyme, Ligase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 138.1;Excitatory neurons: 230.7;Inhibitory neurons: 197.8;Oligodendrocyte precursor cells: 181.0;Oligodendrocytes: 186.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013715, HPA036650, HPA063018" Approved Supported "Nucleoli fibrillar center,Actin filaments,Cytosol" NA NA 110000 "Cluster 30: Non-specific - Translation" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "Nucleoli fibrillar center, Actin filaments" "CAB013715: , HPA036650: AB_2675228, HPA063018: AB_2684922" "unprognostic (1.96e-2)" "unprognostic (1.07e-2)" "unprognostic (3.04e-2)" "unprognostic (1.10e-1)" "unprognostic (4.86e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.24e-5)" "unprognostic (8.81e-2)" "unprognostic (6.56e-2)" "unprognostic (2.38e-3)" "unprognostic (3.38e-1)" "unprognostic (2.24e-1)" "unprognostic (6.72e-2)" "unprognostic (1.18e-1)" "unprognostic (4.89e-1)" "unprognostic (4.49e-2)" "unprognostic (2.03e-2)" 16.2 25.4 10.8 3.7 10.8 4.9 22.2 9.0 15.8 11.5 11.3 14.4 5.2 12.1 13.8 25.2 10.8 4.8 7.7 9.5 11.2 13.6 23.3 13.3 2.0 11.1 9.9 11.3 10.5 10.9 19.2 3.8 11.1 26.2 6.4 8.0 14.6 9.6 15.1 15.4 9.6 8.0 8.6 7.3 12.6 16.4 10.3 3.7 8.9 3.6 5.5 19.9 14.6 12.3 34.7 7.0 39.8 42.6 54.7 53.2 13.9 15.2 21.3 15.9 27.5 27.4 5.9 5.0 12.0 24.3 39.4 33.9 7.5 51.1 23.7 13.6 23.2 27.3 15.5 28.0 9.2 14.8 5.3 43.4 29.0 40.2 30.0 18.8 27.5 25.1 66.5 3.2 2.1 27.3 16.3 22.8 30.4 21.5 22.1 24.1 25.3 6.4 36.1 38.5 45.0 17.0 27.8 12.3 12.7 34.8 24.9 16.8 23.8 12.7 20.6 17.3 3.9 8.7 11.5 42.0 11.7 12.3 17.2 0.5 0.8 0.1 0.6 1.3 0.6 0.7 0.7 0.7 1.0 1.1 1.1 0.8 0.3 0.6 0.8 0.7 1.0 0.6 10.8 10.8 9.0 15.8 9.5 11.2 11.1 9.9 11.1 8.6 10.3 12.3 6.8 32.1 51.7 138.1 8.0 11.6 20.8 14.8 22.2 17.2 17.3 11.7 8.0 2.8 16.5 11.0 27.1 16.0 7.0 5.3 9.8 6.7 66.3 19.1 15.6 8.3 9.0 10.7 230.7 8.3 7.6 10.4 15.8 15.9 7.0 19.5 6.4 17.3 5.8 23.5 197.8 7.3 14.2 3.8 4.3 51.2 9.9 6.1 10.6 58.1 4.3 18.2 4.1 181.0 186.9 7.2 6.4 15.8 9.3 22.8 4.8 7.0 10.5 11.8 6.6 10.0 7.8 20.8 20.5 27.8 15.9 16.3 6.4 43.2 10.0 22.0 ACTN2 ENSG00000077522 "Actinin alpha 2" P35609 1 236664141-236764631 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Actin-binding "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 53 "heart muscle: 772.7;skeletal muscle: 2134.7;tongue: 1262.2" "Cell type enriched" "Detected in some" 11 "Cardiomyocytes: 1762.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 10.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+ RasG12V: 2.0;HEK 293: 1.3;HSkMC: 5.9;hTEC/SVTERT24-B: 2.7" "Region enhanced" "Detected in many" "basal ganglia: 66.6" "Region enhanced" "Detected in all" "basal ganglia: 44.5" "HPA006035, HPA008315" Enhanced Uncertain "Actin filaments" NA NA 25000000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Actin filaments" "HPA006035: AB_1078095, HPA008315: AB_1844543" "unprognostic (1.75e-1)" "unprognostic (1.50e-1)" "unprognostic (2.41e-2)" "unprognostic (1.69e-3)" "unprognostic (2.91e-1)" "unprognostic (4.32e-3)" "unprognostic (7.85e-2)" "unprognostic (2.97e-3)" "unprognostic (2.17e-2)" "unprognostic (2.80e-1)" "unprognostic (2.97e-1)" "unprognostic (2.66e-1)" "unprognostic (2.71e-11)" "unprognostic (1.30e-2)" "unprognostic (1.10e-2)" "unprognostic (4.98e-2)" "unprognostic (1.22e-1)" 0.7 0.2 12.0 0.0 26.3 0.1 0.9 8.0 20.1 0.3 11.0 0.4 0.0 0.5 0.0 21.8 0.5 0.7 772.7 13.2 12.1 0.5 0.3 3.9 0.2 9.7 8.1 1.1 1.6 0.1 0.5 0.1 10.7 16.1 0.0 1.3 18.4 0.1 2134.7 1.3 0.5 1.8 8.0 0.2 3.8 4.2 8.7 0.5 0.7 1262.2 0.1 3.5 0.4 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 1.0 2.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.1 1.3 0.0 0.0 0.2 0.0 0.0 0.2 5.9 0.0 2.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 26.3 8.0 20.1 13.2 12.1 9.7 8.1 10.7 8.0 8.7 14.2 0.3 0.0 0.6 18.6 0.0 0.3 0.4 0.0 1.2 2.6 0.4 0.5 1762.9 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 8.6 0.5 1.2 10.4 0.0 0.0 40.9 0.7 0.0 43.7 3.6 1.4 0.0 0.1 1.8 0.2 0.1 0.0 11.3 0.0 0.0 0.0 0.3 24.6 0.6 1.2 0.0 11.2 0.0 0.0 0.0 24.6 156.9 0.2 0.0 0.4 0.0 0.2 0.0 1.4 0.0 1.2 0.0 66.3 12.4 3.1 2.0 1.2 0.1 0.0 0.4 0.4 0.0 0.2 ACTN3 ENSG00000248746 "Actinin alpha 3" Q08043 11 66546395-66563334 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 72 "skeletal muscle: 1670.4" "Group enriched" "Detected in some" 6 "Early spermatids: 6.3;Late spermatids: 16.2;Skeletal myocytes: 15.2" "Cancer enriched" "Detected in single" 5 "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "HDLM-2: 13.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA006035 Uncertain Uncertain "Actin filaments" NA NA 11000000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 37: Myocytes - Muscle contraction" "Actin filaments" "HPA006035: AB_1078095" "unprognostic (2.54e-1)" "unprognostic (1.07e-1)" "unprognostic (6.16e-2)" "unprognostic (1.46e-1)" "unprognostic (1.70e-1)" "unprognostic (3.35e-4)" "unprognostic (1.40e-3)" "unprognostic (5.37e-3)" "unprognostic (5.09e-3)" "unprognostic (1.19e-1)" "unprognostic (1.17e-1)" "unprognostic (1.66e-2)" "unprognostic (6.71e-9)" "unprognostic (2.06e-1)" "unprognostic (6.98e-2)" "unprognostic (5.16e-2)" "unprognostic (2.48e-1)" 0.2 0.0 0.0 0.1 0.1 0.0 0.2 0.9 0.1 0.2 0.0 0.2 0.0 0.1 0.0 1.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.3 0.1 1670.4 0.1 0.1 0.0 0.0 0.1 0.1 4.0 0.0 0.0 0.3 23.3 0.0 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 6.3 0.0 0.0 0.2 1.8 0.0 0.2 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 16.2 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.2 1.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 ANG "RAA1, RNASE5" ENSG00000214274 Angiogenin P03950 14 20684177-20698971 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Differentiation, Stress response" "Developmental protein, DNA-binding, Endonuclease, Hydrolase, Nuclease, Protein synthesis inhibitor" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 52 "liver: 3018.1" "Cell type enriched" "Detected in many" 24 "Hepatocytes: 4816.3" "Cancer enriched" "Detected in all" 17 "liver cancer: 279.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.5;myeloid DC: 14.5" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Hep G2: 152.2;OE19: 116.1" "Low region specificity" "Detected in all" HPA055896 Approved "Nucleoli,Nucleoli rim,Mitotic chromosome,Actin filaments" "Secreted to blood" Yes No 308000000 410000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Nucleoli, Nucleoli rim, Mitotic chromosome" "Actin filaments" "HPA055896: " "unprognostic (2.50e-2)" "unprognostic (1.82e-1)" "unprognostic (9.77e-2)" "prognostic favorable (6.85e-4)" "unprognostic (5.71e-3)" "unprognostic (6.99e-2)" "prognostic favorable (7.83e-5)" "unprognostic (1.16e-1)" "unprognostic (3.20e-3)" "unprognostic (9.19e-3)" "unprognostic (1.31e-1)" "unprognostic (3.69e-1)" "unprognostic (6.65e-2)" "unprognostic (1.03e-1)" "unprognostic (3.39e-1)" "unprognostic (2.00e-1)" "unprognostic (3.09e-1)" 37.6 3.0 3.6 6.0 3.5 1.0 37.8 3.5 4.9 38.2 5.6 32.6 23.2 23.4 17.9 9.8 30.5 28.5 16.9 3.6 4.9 18.4 3018.1 18.5 3.5 4.5 4.2 58.1 30.8 5.3 5.0 3.8 4.3 32.7 45.7 2.2 52.6 13.3 6.2 27.4 27.1 10.4 4.5 7.4 58.2 10.2 3.7 1.5 8.8 10.5 4.1 24.8 31.4 4.8 3.7 9.9 2.3 0.0 23.9 27.8 0.3 4.8 8.8 1.1 4.0 5.9 5.1 0.4 1.5 12.0 8.0 3.8 2.8 3.1 1.3 18.4 3.8 0.9 5.1 152.2 5.0 4.0 0.5 22.2 2.5 1.5 5.1 11.8 5.7 4.2 0.2 27.0 3.5 0.7 0.9 1.2 0.7 116.1 10.7 0.7 3.9 11.3 2.3 2.9 0.0 0.4 4.6 1.7 6.5 5.1 4.0 0.7 6.0 1.9 2.8 1.7 0.7 5.9 4.8 0.5 3.2 2.0 5.0 0.0 24.5 0.0 0.6 2.9 0.4 5.8 1.2 1.1 14.5 4.9 0.3 0.2 0.4 0.0 0.1 2.3 0.8 7.1 3.6 3.5 3.5 4.9 3.6 4.9 4.5 4.2 4.3 4.5 3.7 4.8 9.7 28.9 17.7 0.0 9.7 27.1 43.3 39.2 14.2 0.1 33.8 24.8 0.8 194.5 24.6 11.0 0.0 1.6 0.7 32.5 11.7 40.0 1.0 6.2 9.7 11.0 71.0 27.8 0.0 31.6 5.3 48.8 56.1 24.9 0.0 10.7 62.4 4816.3 15.9 0.0 0.0 171.9 12.2 95.9 18.7 2.9 71.1 13.8 23.2 0.0 4.9 10.1 0.0 0.0 0.0 21.6 33.3 24.0 11.7 43.7 91.3 61.2 76.5 0.6 13.1 29.7 17.7 1.0 1.3 9.4 52.4 9.3 5.6 0.5 51.6 39.2 ANKRD23 "DARP, FLJ32449, MARP3" ENSG00000163126 "Ankyrin repeat domain 23" Q86SG2 2 96824526-96857934 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 39 "skeletal muscle: 1438.6;tongue: 448.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 5.0;Respiratory ciliated cells: 7.4;Rod photoreceptor cells: 5.2;Skeletal myocytes: 6.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "Karpas-707: 38.5" "Low region specificity" "Detected in many" HPA036201 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 2: Karpas-707 - Immune response" "Cluster 37: Myocytes - Muscle contraction" "Nucleoplasm, Cytosol" "Actin filaments" "HPA036201: AB_10673347" "unprognostic (2.48e-1)" "unprognostic (7.83e-4)" "unprognostic (4.93e-4)" "unprognostic (1.21e-2)" "unprognostic (4.28e-1)" "unprognostic (3.28e-1)" "unprognostic (3.27e-2)" "unprognostic (6.66e-2)" "unprognostic (2.46e-2)" "unprognostic (3.59e-2)" "unprognostic (1.81e-4)" "unprognostic (1.43e-1)" "unprognostic (2.04e-6)" "unprognostic (2.70e-1)" "unprognostic (1.39e-1)" "unprognostic (1.54e-1)" "unprognostic (2.70e-4)" 0.8 0.9 1.6 0.4 2.1 0.7 1.2 2.2 2.1 1.4 0.6 1.3 0.8 1.8 0.0 6.0 2.5 0.2 24.2 1.5 1.4 0.7 2.2 1.0 0.6 2.5 1.6 1.7 1.6 0.3 10.4 0.2 1.8 5.3 0.1 0.1 18.5 0.3 1438.6 2.5 1.3 0.2 1.5 2.3 0.7 0.7 1.9 0.6 1.1 448.6 0.4 1.2 1.1 2.3 0.5 0.7 0.4 0.8 0.0 0.2 1.1 0.3 0.1 0.2 0.1 0.1 0.2 0.4 0.2 0.1 0.3 0.3 0.3 0.3 0.2 1.1 1.0 0.5 0.8 0.2 0.1 0.8 1.8 0.3 0.3 0.6 0.0 0.2 0.1 1.5 0.9 38.5 0.3 0.9 0.5 0.8 0.4 0.1 0.3 1.4 0.0 5.0 0.2 0.9 1.4 0.2 0.3 0.7 0.0 0.2 1.1 0.0 0.3 0.5 0.6 0.7 0.1 1.7 0.7 0.3 0.4 1.1 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 2.1 2.2 2.1 1.5 1.4 2.5 1.6 1.8 1.5 1.9 2.3 1.1 0.0 1.1 2.0 0.5 0.8 0.5 0.4 0.6 2.6 0.8 2.3 5.0 0.0 1.5 0.0 2.1 0.4 2.1 0.9 0.0 0.3 3.3 1.3 1.9 0.8 0.0 0.4 2.8 1.1 0.2 1.3 0.5 0.7 1.3 1.1 1.4 1.2 0.2 1.7 2.7 1.0 0.0 0.6 0.3 1.8 1.5 0.6 0.0 1.0 0.2 1.1 1.0 0.5 2.9 0.1 0.3 3.0 0.4 0.3 0.6 0.2 7.4 5.2 0.0 6.1 1.6 1.3 0.4 0.4 1.3 0.3 1.1 0.7 0.9 0.2 ANKRD62 DKFZp779B1634 ENSG00000181626 "Ankyrin repeat domain 62" A6NC57 18 12093843-12129764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "brain: 1.1;pancreas: 1.0;testis: 1.6" "Cell type enriched" "Detected in some" 5 "Spermatocytes: 92.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059835 Enhanced Uncertain "Nucleoplasm,Nuclear bodies,Actin filaments" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "Actin filaments" "HPA059835: AB_2684136" "unprognostic (2.45e-2)" "unprognostic (1.18e-1)" "unprognostic (2.37e-3)" "unprognostic (9.46e-2)" "unprognostic (3.01e-1)" "unprognostic (1.98e-1)" "unprognostic (6.61e-2)" "unprognostic (7.95e-2)" "unprognostic (3.27e-1)" "unprognostic (2.55e-4)" "unprognostic (1.13e-1)" "unprognostic (3.28e-2)" "unprognostic (4.52e-3)" "unprognostic (8.70e-2)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.4 0.0 0.6 0.0 0.7 0.0 0.0 0.4 0.1 0.0 1.3 0.3 0.1 0.4 0.3 0.0 0.0 1.7 0.4 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 2.2 0.1 0.2 0.5 0.0 0.0 16.5 1.7 0.6 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.6 0.8 2.6 0.6 0.2 0.0 1.0 0.0 0.1 1.0 1.0 0.2 0.5 1.1 0.4 0.0 0.8 0.2 0.0 0.0 0.9 0.0 1.3 0.3 92.8 15.8 0.5 1.1 0.0 0.2 0.1 0.2 0.5 APBB3 FE65L2 ENSG00000113108 "Amyloid beta precursor protein binding family B member 3" O95704 5 140558268-140564781 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 63.1;Late spermatids: 43.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SCLC-21H: 6.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005571, HPA076196" Approved Approved "Actin filaments,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 43: Testis - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 34: Spermatids - Unknown function" "Actin filaments, Cytosol" "HPA005571: AB_1844912, HPA076196: " "unprognostic (7.63e-2)" "unprognostic (4.58e-2)" "unprognostic (1.13e-2)" "unprognostic (1.36e-2)" "unprognostic (1.29e-1)" "unprognostic (1.40e-3)" "unprognostic (1.44e-1)" "unprognostic (5.06e-2)" "unprognostic (7.22e-2)" "unprognostic (1.98e-1)" "prognostic favorable (6.79e-4)" "unprognostic (9.65e-2)" "prognostic unfavorable (2.06e-6)" "unprognostic (1.06e-1)" "unprognostic (4.59e-1)" "unprognostic (9.38e-2)" "unprognostic (4.67e-2)" 2.2 3.9 7.2 0.0 7.6 0.7 2.3 7.3 10.1 2.0 3.7 2.0 0.2 2.5 1.5 1.5 2.6 0.5 2.3 8.1 9.6 2.5 3.1 1.4 0.5 8.2 6.0 2.5 2.6 1.6 9.9 1.4 8.8 1.9 0.7 6.4 2.5 1.7 2.3 2.0 2.1 0.9 4.9 2.2 2.6 8.5 7.2 0.6 3.1 1.2 0.7 2.2 1.8 5.9 0.4 0.4 0.2 2.0 0.0 0.8 3.3 1.0 1.2 1.3 2.6 1.0 1.1 1.3 2.0 1.7 0.8 0.7 0.0 1.4 0.4 1.6 0.6 0.6 4.0 0.1 2.2 0.7 0.8 5.0 0.6 1.2 1.0 0.3 0.8 3.6 0.1 4.4 1.5 0.9 0.2 1.3 0.8 0.5 2.5 0.3 0.4 1.1 1.2 1.0 6.4 3.0 2.8 0.9 3.7 0.2 2.7 2.8 0.7 0.3 0.6 0.0 0.2 1.7 1.3 0.1 0.8 0.4 0.5 5.6 0.7 0.0 0.7 1.8 0.4 0.2 0.4 0.6 0.6 0.6 0.3 0.6 1.9 0.4 0.3 1.0 0.5 0.6 7.2 7.6 7.3 10.1 8.1 9.6 8.2 6.0 8.8 4.9 7.2 5.9 8.3 3.2 9.3 25.8 6.8 2.8 3.4 5.7 4.0 29.4 9.4 8.3 2.1 14.3 10.1 5.5 0.0 11.7 6.3 5.4 5.9 3.9 63.1 3.9 6.8 6.1 5.4 5.2 13.1 1.5 11.9 7.8 15.3 5.3 10.8 6.2 7.1 17.0 14.5 18.5 13.5 2.8 14.2 18.0 14.2 43.6 5.6 13.8 7.2 8.4 12.6 13.5 5.2 8.5 15.6 2.4 3.7 4.9 3.9 2.3 8.6 3.3 5.6 16.5 0.0 6.4 7.2 19.2 6.9 2.9 2.8 11.8 5.2 4.9 3.6 3.1 APPL1 APPL ENSG00000157500 "Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1" Q9UKG1 3 57227726-57278105 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 28.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011138 Approved Approved "Vesicles,Plasma membrane,Actin filaments,Cytosol" NA No 10000 "Cluster 37: B-cells - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 32: U-937 - Innate immune response" "Cluster 57: B-cells - Immune response" "Vesicles, Plasma membrane" "Actin filaments, Cytosol" "HPA011138: AB_1844959" "unprognostic (1.39e-1)" "unprognostic (3.45e-2)" "unprognostic (1.06e-2)" "unprognostic (2.01e-1)" "unprognostic (3.68e-2)" "unprognostic (2.31e-3)" "unprognostic (1.30e-3)" "unprognostic (1.81e-2)" "unprognostic (1.05e-1)" "unprognostic (8.36e-2)" "unprognostic (9.05e-3)" "unprognostic (5.55e-2)" "prognostic favorable (7.26e-5)" "unprognostic (3.99e-2)" "unprognostic (8.76e-2)" "unprognostic (1.12e-2)" "unprognostic (1.55e-1)" 15.6 11.6 9.5 14.8 9.7 15.1 18.9 12.9 11.3 17.1 6.8 14.2 12.6 17.1 10.6 16.9 11.7 13.0 24.7 9.7 11.3 16.5 12.9 13.6 16.7 9.8 10.1 22.7 29.6 25.1 7.8 14.3 10.1 15.0 14.0 13.5 15.2 14.4 44.2 20.1 14.6 15.3 10.4 15.8 15.2 8.0 10.2 18.9 19.8 26.6 19.6 13.4 11.9 10.7 30.2 12.9 12.2 45.4 21.2 29.7 26.2 15.5 9.5 15.4 17.8 14.9 17.5 47.3 6.2 24.6 24.7 5.9 33.7 27.3 26.6 36.1 15.0 27.6 19.5 16.1 22.7 59.6 19.1 21.8 24.3 19.3 21.3 31.3 25.3 30.2 9.0 30.0 17.8 10.4 48.7 15.4 19.5 21.6 21.7 1.7 49.1 26.1 27.7 16.7 12.5 26.5 21.1 32.3 21.0 16.7 15.7 39.6 23.4 25.1 17.5 37.4 29.9 27.0 41.8 33.2 27.4 29.1 17.1 2.0 5.3 3.8 3.7 4.5 4.9 17.9 3.8 3.3 10.9 28.3 3.3 2.5 1.4 7.4 3.6 18.0 1.9 2.7 9.5 9.7 12.9 11.3 9.7 11.3 9.8 10.1 10.1 10.4 10.2 10.7 82.9 51.3 45.5 19.6 106.6 52.9 47.3 46.9 83.6 40.5 67.2 92.8 100.1 47.1 47.4 42.3 31.3 46.9 70.9 29.0 58.7 58.6 42.5 35.4 92.8 66.2 45.6 20.0 49.7 60.3 44.7 68.6 40.2 59.4 23.4 60.8 40.0 44.1 52.2 52.2 50.4 36.2 42.7 68.6 50.6 22.1 73.0 71.0 19.6 33.7 87.8 56.6 56.7 43.2 62.2 51.7 25.5 76.0 62.8 38.7 41.0 58.8 18.1 55.4 52.6 94.3 61.2 64.9 44.2 105.7 69.6 28.0 45.4 73.7 49.1 25.8 ATP12A "ATP1AL1, H-K-ATPase, HK" ENSG00000075673 "ATPase H+/K+ transporting non-gastric alpha2 subunit" P54707 13 24680408-24712472 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Potassium transport, Sodium transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 11.2;kidney: 5.4;lymphoid tissue: 14.8;placenta: 5.6;skin 1: 6.2" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 75.6;Club cells: 49.2" "Cancer enhanced" "Detected in many" "testis cancer: 12.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "SuSa: 4.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA039526 Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane, Actin filaments" Cytosol "HPA039526: AB_10673534" "unprognostic (8.33e-3)" "unprognostic (3.58e-2)" "unprognostic (2.93e-1)" "unprognostic (5.21e-3)" "unprognostic (2.58e-1)" "unprognostic (1.21e-2)" "unprognostic (8.03e-3)" "unprognostic (2.64e-1)" "unprognostic (1.50e-1)" "unprognostic (1.18e-1)" "unprognostic (3.39e-1)" "unprognostic (2.24e-1)" "unprognostic (1.78e-1)" "unprognostic (1.67e-1)" "unprognostic (6.80e-2)" "unprognostic (8.22e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.1 0.0 5.4 0.0 0.6 0.0 0.0 0.1 0.0 0.1 0.6 0.0 5.6 0.0 0.2 2.0 0.0 0.1 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 14.8 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.7 1.0 0.0 0.0 0.0 75.6 0.0 0.0 0.2 0.3 0.4 0.0 49.2 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.3 0.5 0.0 0.0 0.0 0.9 0.0 0.0 0.4 0.0 2.2 1.3 0.0 0.0 0.0 0.0 0.0 0.7 0.2 8.2 0.0 0.0 0.1 0.3 0.1 0.0 1.0 0.0 0.0 0.0 1.0 0.6 0.1 1.2 0.0 0.0 0.2 0.0 0.1 13.6 0.0 0.0 0.0 1.8 1.0 1.1 0.0 0.0 0.0 0.1 0.0 0.1 1.3 AXL "ARK, JTK11, Tyro7, UFO" ENSG00000167601 "AXL receptor tyrosine kinase" P30530 19 41219223-41261766 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Differentiation, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Oncogene, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 147.2;Kupffer cells: 187.5;Langerhans cells: 185.5;Prostatic glandular cells: 123.4;Sertoli cells: 210.4;Smooth muscle cells: 171.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 11.1;plasmacytoid DC: 25.7" "Group enriched" "Detected in many" 12 "dendritic cells: 25.7;NK-cells: 11.1" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 501.2;U-251 MG: 540.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032501, HPA037422, HPA037423, HPA075217" Uncertain Supported "Vesicles,Plasma membrane,Actin filaments" NA Yes 12100000 72000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "Vesicles, Actin filaments" "CAB032501: AB_2062572, HPA037422: AB_10672347, HPA037423: AB_2675470, HPA075217: " "unprognostic (2.20e-1)" "unprognostic (2.02e-1)" "unprognostic (6.79e-3)" "unprognostic (1.01e-1)" "unprognostic (1.40e-1)" "unprognostic (8.49e-3)" "unprognostic (2.42e-1)" "unprognostic (1.74e-1)" "unprognostic (3.15e-2)" "unprognostic (2.82e-2)" "unprognostic (9.57e-3)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.53e-7)" "unprognostic (1.16e-3)" "unprognostic (1.52e-2)" "unprognostic (5.56e-2)" "unprognostic (4.83e-3)" 43.6 18.8 17.5 15.5 22.6 1.7 26.6 19.7 17.7 36.1 12.4 42.5 11.7 34.4 8.7 17.6 25.4 22.4 26.7 16.6 18.8 9.8 15.0 25.9 6.2 26.8 20.6 24.7 6.3 10.7 7.3 34.2 22.1 19.2 12.6 5.8 10.6 24.6 9.4 20.0 19.0 37.1 20.9 37.7 21.4 18.6 24.0 7.2 16.6 11.3 5.0 32.5 25.2 21.9 408.0 160.0 9.7 1.3 34.6 34.7 0.5 314.5 280.2 450.9 278.2 8.5 185.5 0.2 124.7 501.2 235.3 33.3 0.4 211.8 384.8 0.7 0.3 0.0 100.4 6.3 125.0 0.3 0.3 26.4 3.8 266.7 409.5 254.8 169.8 0.1 15.8 0.5 284.6 0.5 0.2 0.4 4.1 1.0 76.3 0.2 165.3 0.3 202.3 0.2 0.1 0.1 81.5 0.6 1.8 57.4 0.9 7.2 351.8 317.8 214.6 307.7 540.8 0.5 0.9 1.0 211.5 0.5 241.8 1.5 0.3 0.2 0.1 0.4 0.2 0.1 0.3 0.1 6.0 0.1 0.3 0.3 0.3 11.1 0.2 25.7 0.4 0.3 17.5 22.6 19.7 17.7 16.6 18.8 26.8 20.6 22.1 20.9 24.0 21.9 13.5 9.6 3.6 35.9 1.9 41.7 88.3 10.3 3.4 0.5 2.3 14.2 8.6 1.5 4.4 5.5 0.0 4.2 0.8 0.1 0.0 6.9 8.7 6.0 45.8 17.7 0.0 0.0 0.8 0.2 2.1 147.2 1.5 5.4 0.0 17.3 11.0 1.2 28.8 1.7 1.1 0.1 2.0 187.5 185.5 5.5 61.5 61.4 26.6 30.9 3.1 26.8 0.0 11.1 0.5 14.5 0.1 79.7 0.8 123.4 0.3 0.1 2.8 1.2 210.4 38.1 171.1 1.9 2.0 1.2 29.1 11.5 3.6 2.5 0.1 28.0 BBOX1 "BBH, BBOX, G-BBH, gamma-BBH" ENSG00000129151 "Gamma-butyrobetaine hydroxylase 1" O75936 11 27040725-27127809 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carnitine biosynthesis" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 467.9;liver: 131.9" "Cell type enriched" "Detected in many" 7 "Proximal tubular cells: 1623.0" "Group enriched" "Detected in many" 6 "glioma: 23.7;renal cancer: 59.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "hTCEpi: 13.7;RPTEC TERT1: 7.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA007600, HPA027823" Enhanced Approved Uncertain "Vesicles,Actin filaments" NA NA 35000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "Actin filaments" "HPA007600: AB_1845284, HPA027823: AB_10602394" "unprognostic (9.96e-3)" "unprognostic (1.80e-2)" "unprognostic (8.17e-2)" "prognostic unfavorable (6.65e-4)" "unprognostic (7.03e-2)" "unprognostic (6.66e-2)" "unprognostic (7.05e-3)" "unprognostic (1.13e-2)" "unprognostic (3.03e-1)" "unprognostic (6.89e-2)" "unprognostic (2.03e-2)" "unprognostic (1.60e-1)" "prognostic favorable (1.45e-5)" "unprognostic (1.71e-2)" "unprognostic (2.70e-1)" "unprognostic (3.22e-1)" "unprognostic (1.73e-3)" 1.4 0.0 24.3 0.0 23.4 0.0 25.1 28.8 34.0 5.1 17.3 0.2 0.0 0.1 8.1 17.5 9.0 9.6 0.0 22.8 25.6 467.9 131.9 0.3 0.1 27.2 33.1 0.0 0.8 0.0 6.9 0.3 35.0 0.5 0.0 0.4 6.1 4.1 0.9 51.8 0.0 0.0 28.8 0.0 0.2 0.1 25.2 1.1 9.6 0.0 0.6 0.1 11.3 27.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.9 13.7 0.0 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.2 2.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.3 23.4 28.8 34.0 22.8 25.6 27.2 33.1 35.0 28.8 25.2 27.0 0.1 0.0 0.6 66.3 5.3 8.2 9.0 80.9 0.6 0.0 16.3 11.0 0.0 15.7 18.1 46.0 0.0 0.3 0.2 0.0 223.0 0.7 1.1 10.3 0.1 0.3 0.0 0.0 1.1 0.0 0.0 0.4 0.0 0.9 0.0 0.1 0.4 27.9 0.0 0.0 0.8 0.0 12.2 0.6 1.1 1.1 0.0 7.1 1.8 4.7 0.0 13.8 0.0 2.0 0.3 0.1 0.0 0.4 0.0 0.2 0.0 1623.0 9.4 0.4 0.0 0.0 1.4 0.0 0.6 16.9 35.8 0.3 5.0 0.0 0.0 2.6 BCO1 "BCDO, BCDO1, BCMO, BCMO1, FLJ10730" ENSG00000135697 "Beta-carotene oxygenase 1" Q9HAY6 16 81238689-81291142 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 5.0;intestine: 14.6" "Cell type enhanced" "Detected in some" "Astrocytes: 6.2;Distal enterocytes: 4.8;Excitatory neurons: 8.0;Intestinal goblet cells: 5.5;Proximal enterocytes: 13.6;Proximal tubular cells: 8.8" "Cancer enhanced" "Detected in many" "renal cancer: 3.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 11.5;EFO-21: 8.7;HAP1: 3.3;NTERA-2: 4.6;RPTEC TERT1: 8.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA043811 Uncertain "Actin filaments,Centriolar satellite" NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Actin filaments, Centriolar satellite" "HPA043811: AB_10962487" "unprognostic (2.78e-1)" "unprognostic (3.88e-3)" "unprognostic (2.61e-1)" "unprognostic (3.32e-1)" "unprognostic (4.05e-2)" "unprognostic (8.01e-4)" "unprognostic (1.65e-1)" "unprognostic (2.99e-2)" "unprognostic (1.58e-3)" "unprognostic (7.26e-2)" "unprognostic (2.97e-2)" "unprognostic (1.08e-3)" "unprognostic (1.46e-1)" "unprognostic (1.90e-2)" "unprognostic (2.48e-1)" "unprognostic (5.07e-2)" "unprognostic (1.09e-1)" 0.0 0.0 1.8 0.2 1.3 0.0 0.1 0.0 1.2 0.2 5.0 2.6 9.3 0.6 0.2 0.3 0.4 1.2 0.0 2.5 0.2 3.5 0.8 0.2 0.0 0.4 0.4 0.9 0.3 0.0 0.7 0.0 0.1 0.5 3.0 0.2 0.5 1.5 0.1 0.3 14.6 0.3 0.1 0.0 1.9 0.1 0.7 0.2 0.1 0.0 0.0 0.2 0.4 0.6 0.0 11.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.3 2.3 0.0 8.7 0.0 0.3 0.1 3.3 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 4.6 0.8 0.0 0.0 0.0 0.0 8.6 0.3 0.3 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.3 0.0 1.2 2.5 0.2 0.4 0.4 0.1 0.1 0.7 0.6 0.0 0.0 0.0 6.2 0.0 0.0 0.3 0.0 0.6 0.0 0.1 0.0 0.2 0.0 0.0 1.8 0.0 0.5 0.0 4.8 0.0 0.6 0.1 0.9 1.1 0.1 1.2 0.0 8.0 0.0 0.0 0.2 0.0 4.0 0.0 0.1 0.4 0.3 0.1 0.0 3.7 5.5 0.0 0.0 0.0 0.3 1.5 0.1 0.0 1.0 0.0 0.0 0.0 2.5 1.0 0.6 2.1 1.2 0.0 0.1 13.6 8.8 0.0 0.0 0.0 0.1 0.1 0.4 0.2 0.7 0.0 0.3 0.1 0.0 3.0 0.7 BPIFB4 "C20orf186, dJ726C3.5, LPLUNC4" ENSG00000186191 "BPI fold containing family B member 4" P59827 20 33079644-33111751 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "pituitary gland: 8.4" "Cell type enhanced" "Detected in single" "Basal respiratory cells: 2.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HSkMC: 2.3;U-2 OS: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA047388 Approved "Actin filaments,Cytosol" "Secreted - unknown location" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Actin filaments, Cytosol" "HPA047388: " "unprognostic (1.32e-1)" "unprognostic (1.16e-1)" "unprognostic (1.61e-1)" "unprognostic (2.75e-2)" "unprognostic (1.31e-3)" "unprognostic (4.70e-2)" "unprognostic (3.42e-2)" "unprognostic (2.03e-1)" "unprognostic (3.98e-4)" "unprognostic (1.31e-1)" "unprognostic (1.82e-1)" "unprognostic (8.97e-2)" 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 8.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.6 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 CD274 "B7-H, B7-H1, B7H1, PD-L1, PDCD1LG1, PDL1" ENSG00000120217 "CD274 molecule" Q9NZQ7 9 5450503-5470566 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 16.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 27.7;granulocytes: 28.4;Langerhans cells: 50.9;monocytes: 42.4;Syncytiotrophoblasts: 44.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 6.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.6" "Cell line enhanced" "Detected in many" "HDLM-2: 89.6;HHSteC: 55.5;U-251 MG: 98.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003528, CAB076385" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane, Actin filaments" Nucleoplasm "CAB076385: AB_2687655, HPA003528: " "prognostic favorable (8.89e-4)" "unprognostic (4.54e-2)" "prognostic favorable (1.64e-5)" "unprognostic (1.27e-2)" "unprognostic (2.96e-2)" "unprognostic (1.08e-1)" "unprognostic (4.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.68e-2)" "unprognostic (5.67e-4)" "unprognostic (7.39e-3)" "unprognostic (1.69e-2)" "unprognostic (1.24e-2)" "unprognostic (1.35e-1)" "unprognostic (1.49e-2)" "unprognostic (2.67e-1)" "unprognostic (9.02e-2)" 2.6 2.0 1.0 10.3 0.9 1.9 1.5 0.9 1.2 1.8 0.6 1.4 2.7 1.5 1.8 2.5 1.8 4.0 8.9 0.8 1.9 2.6 3.4 16.8 6.6 1.8 1.6 1.5 1.9 5.0 2.6 6.8 2.0 2.0 2.1 1.2 1.5 1.5 4.5 0.7 1.9 2.2 1.7 10.2 1.9 0.9 1.6 13.0 3.5 4.3 5.3 7.2 1.3 1.1 15.6 0.2 0.0 0.5 0.1 0.1 0.0 30.5 25.7 7.7 10.4 0.0 5.0 0.2 0.6 0.8 3.8 0.6 0.0 13.2 24.6 89.6 0.0 9.0 0.3 0.0 55.5 0.0 0.0 0.5 0.1 15.7 22.9 7.7 15.0 0.9 0.0 2.9 23.4 0.0 0.4 0.1 0.0 0.0 0.3 0.1 4.2 0.8 1.6 0.3 0.0 0.3 0.4 2.4 1.9 2.2 0.1 0.3 28.1 16.1 5.1 0.5 98.1 0.5 0.2 0.3 5.4 0.3 0.2 6.6 0.0 0.2 0.7 0.1 1.2 0.5 1.4 1.1 0.0 0.1 0.7 0.4 3.6 0.3 0.0 0.0 0.7 0.4 1.0 0.9 0.9 1.2 0.8 1.9 1.8 1.6 2.0 1.7 1.6 1.1 3.0 12.8 11.4 0.7 1.9 4.6 1.5 4.4 1.8 1.4 1.4 1.3 7.8 0.0 2.9 0.0 0.0 6.1 2.4 2.6 0.0 5.9 1.0 1.4 0.3 5.5 0.0 3.2 1.9 4.4 27.7 1.9 0.5 0.9 28.4 0.2 7.1 0.8 5.7 0.0 3.3 0.5 4.1 2.9 50.9 0.2 0.3 4.2 3.6 8.4 42.4 0.5 1.0 1.0 0.9 19.0 0.1 0.4 2.2 2.1 1.9 0.4 4.0 0.2 0.0 2.3 0.9 1.0 0.8 1.2 2.6 44.5 3.1 0.1 0.4 2.0 CNNM4 "ACDP4, KIAA1592" ENSG00000158158 "Cyclin and CBS domain divalent metal cation transport mediator 4" Q6P4Q7 2 96760902-96811874 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Biomineralization, Ion transport, Sensory transduction, Transport, Vision" "Amelogenesis imperfecta, Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 38.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 112.6;Distal enterocytes: 103.4;Rod photoreceptor cells: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "SK-BR-3: 45.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017732 Enhanced Uncertain "Plasma membrane,Actin filaments" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Actin filaments" "Plasma membrane" "HPA017732: AB_1847395" "unprognostic (1.98e-3)" "unprognostic (8.95e-3)" "unprognostic (1.11e-1)" "prognostic unfavorable (9.14e-4)" "unprognostic (3.42e-2)" "unprognostic (5.28e-2)" "unprognostic (1.54e-3)" "unprognostic (3.36e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.75e-4)" "unprognostic (4.75e-3)" "unprognostic (3.72e-1)" "unprognostic (8.14e-2)" "unprognostic (3.13e-1)" "unprognostic (3.44e-2)" "unprognostic (1.15e-2)" "unprognostic (1.06e-1)" 2.8 3.6 5.0 6.1 6.8 4.9 7.0 11.2 5.4 5.8 2.8 32.4 6.2 4.0 4.7 7.1 10.4 4.4 12.5 4.9 4.4 6.8 4.4 8.0 4.6 4.1 4.5 5.1 7.4 6.3 9.1 5.8 4.2 5.7 34.3 38.8 6.8 5.1 24.8 7.2 11.3 4.7 3.5 5.3 12.8 7.9 4.5 3.5 9.5 13.1 4.9 5.5 6.4 5.7 11.1 7.2 5.7 10.5 5.8 3.9 15.6 4.8 6.8 6.9 9.3 13.2 11.8 8.1 13.5 5.0 9.5 14.1 14.9 8.1 6.3 16.3 11.7 6.4 4.8 7.2 8.1 3.1 6.2 3.8 10.0 11.0 6.6 4.6 3.8 8.0 3.3 22.3 3.6 15.7 6.6 4.5 7.5 20.5 9.8 9.7 2.6 9.3 6.9 8.6 26.7 8.0 9.1 45.7 6.8 15.9 22.3 5.3 3.4 4.0 8.9 8.8 5.4 7.7 6.6 4.0 5.9 6.1 7.2 1.2 0.4 0.1 0.8 0.4 0.2 0.9 0.4 0.4 0.6 0.5 0.2 0.5 0.2 0.2 0.7 0.4 0.2 0.3 5.0 6.8 11.2 5.4 4.9 4.4 4.1 4.5 4.2 3.5 4.5 5.7 4.5 38.5 7.7 12.4 6.4 5.7 4.9 4.0 4.6 43.1 14.7 11.2 14.1 4.3 11.6 7.3 112.6 5.4 6.1 103.4 0.0 3.2 4.9 14.3 4.4 4.0 10.1 0.8 9.8 4.2 1.7 3.2 12.2 16.1 1.3 5.9 2.2 3.3 3.3 33.7 8.3 26.4 6.1 5.4 4.8 1.6 0.9 5.9 0.0 8.4 2.3 8.3 2.1 11.1 14.6 5.2 21.3 1.2 4.5 4.1 22.3 1.2 10.6 51.5 0.0 4.6 4.3 4.6 2.5 7.3 4.1 6.7 5.4 6.7 26.5 6.1 CNR1 "CANN6, CB-R, CB1, CB1A, CB1K5, CNR" ENSG00000118432 "Cannabinoid receptor 1" P21554 6 88139864-88166359 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 23.0;brain: 25.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 44.6;Inhibitory neurons: 200.3;Sertoli cells: 98.6" "Cancer enriched" "Detected in many" 13 "glioma: 12.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC diff: 81.4;HSkMC: 53.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042256, HPA069945" Enhanced Supported Supported "Plasma membrane,Actin filaments" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Actin filaments" "HPA042256: AB_2677917, HPA069945: " "unprognostic (1.28e-1)" "unprognostic (7.04e-2)" "unprognostic (4.61e-2)" "unprognostic (4.08e-3)" "unprognostic (1.21e-1)" "unprognostic (1.07e-3)" "unprognostic (1.37e-1)" "unprognostic (2.07e-2)" "unprognostic (2.49e-1)" "unprognostic (1.16e-2)" "unprognostic (2.74e-2)" "unprognostic (2.68e-1)" "unprognostic (1.70e-1)" "unprognostic (5.59e-3)" "unprognostic (2.68e-3)" "unprognostic (5.88e-2)" "unprognostic (7.00e-2)" 23.0 5.4 10.4 3.5 25.1 0.7 16.9 7.5 22.8 5.7 0.0 12.3 1.1 6.9 2.6 2.4 11.2 2.0 1.0 19.5 11.8 0.9 0.1 4.0 4.4 9.9 1.1 3.8 1.5 0.5 20.7 3.1 0.5 2.9 2.9 1.5 2.6 2.1 2.4 3.8 10.5 3.6 0.0 1.7 4.3 1.2 18.0 1.3 5.1 1.2 6.6 4.1 5.1 3.0 0.0 0.1 3.8 0.0 81.4 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.2 1.9 2.9 0.0 5.3 0.0 0.0 53.8 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.4 0.5 0.0 6.8 0.0 1.7 0.1 0.0 0.0 0.0 0.3 0.0 1.4 4.9 0.0 0.0 0.1 0.0 0.0 1.6 7.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.4 25.1 7.5 22.8 19.5 11.8 9.9 1.1 0.5 0.0 18.0 3.0 3.4 0.0 10.4 3.6 7.1 0.6 0.5 0.0 0.0 1.7 0.1 0.4 0.9 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.2 0.0 0.4 3.8 0.0 0.0 44.6 0.0 0.0 0.9 1.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 200.3 0.0 0.0 0.3 0.8 0.0 1.5 0.2 0.0 5.6 0.0 0.0 0.0 9.0 3.2 0.0 0.1 0.4 4.2 0.0 0.0 0.0 0.0 0.2 98.6 6.4 12.4 0.0 0.5 0.2 0.1 0.1 0.5 0.0 0.0 0.8 CORIN "ATC2, CRN, Lrp4, PRSC, TMPRSS10" ENSG00000145244 "Corin, serine peptidase" Q9Y5Q5 4 47593999-47838106 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "heart muscle: 56.9" "Cell type enriched" "Detected in some" 6 "Cardiomyocytes: 69.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "ASC TERT1: 44.0" "Region enhanced" "Detected in some" "basal ganglia: 2.6" "Low region specificity" "Detected in some" HPA070941 Approved "Nuclear bodies,Plasma membrane,Actin filaments" "Intracellular and membrane" Yes No "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Nuclear bodies, Actin filaments" "HPA070941: AB_2686324" "unprognostic (1.05e-1)" "unprognostic (2.52e-1)" "unprognostic (1.14e-1)" "unprognostic (1.93e-1)" "unprognostic (2.10e-1)" "unprognostic (3.18e-1)" "unprognostic (3.58e-4)" "unprognostic (3.19e-1)" "unprognostic (3.67e-2)" "unprognostic (8.22e-2)" "unprognostic (9.78e-2)" "unprognostic (6.53e-2)" "unprognostic (1.18e-1)" "unprognostic (2.86e-2)" "unprognostic (5.18e-2)" "unprognostic (7.22e-2)" "unprognostic (1.33e-2)" 0.4 0.1 0.1 0.1 0.1 0.0 1.0 0.1 0.2 2.1 0.6 0.3 0.1 4.5 0.6 0.9 1.4 4.5 56.9 0.0 0.3 1.0 0.1 1.9 0.0 0.7 0.6 0.5 0.2 1.1 1.9 0.4 0.1 2.3 0.0 0.3 0.4 6.1 0.1 7.5 0.3 0.7 0.1 1.1 0.5 2.5 0.3 0.1 0.1 0.1 0.1 1.2 3.9 0.1 0.0 0.0 0.1 0.3 10.3 44.0 0.0 2.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 2.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.9 1.4 0.0 0.3 0.2 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.3 0.7 0.6 0.1 0.1 0.3 0.1 0.3 0.0 7.5 1.0 0.0 3.8 0.3 0.0 0.0 1.0 8.3 0.3 69.4 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.1 1.3 1.0 0.0 0.0 6.5 0.0 0.0 9.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 10.8 0.0 0.0 0.6 5.5 2.0 4.7 0.1 5.4 1.0 0.0 0.7 0.0 2.0 3.9 0.0 0.0 2.6 0.0 0.6 0.0 0.2 0.0 0.3 0.0 0.3 2.3 4.6 4.4 0.1 2.7 0.0 0.6 0.1 0.0 0.3 CYP20A1 CYP-M ENSG00000119004 "Cytochrome P450 family 20 subfamily A member 1" Q6UW02 2 203238977-203306026 "Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA055872, HPA058461" Uncertain Uncertain "Nucleoplasm,Plasma membrane,Cell Junctions,Actin filaments" No No "Cluster 24: B-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Cell Junctions, Actin filaments" Nucleoplasm "HPA055872: AB_2682951, HPA058461: AB_2683725" "unprognostic (4.72e-2)" "unprognostic (2.06e-2)" "unprognostic (1.20e-2)" "unprognostic (2.14e-2)" "unprognostic (1.42e-1)" "unprognostic (3.06e-2)" "unprognostic (5.21e-2)" "unprognostic (2.58e-2)" "unprognostic (4.21e-2)" "unprognostic (2.62e-2)" "unprognostic (4.53e-2)" "unprognostic (4.42e-2)" "unprognostic (7.64e-3)" "unprognostic (9.39e-2)" "unprognostic (2.18e-1)" "unprognostic (1.23e-2)" "unprognostic (1.95e-3)" 3.1 3.2 3.1 2.1 4.3 2.2 2.4 4.1 3.4 2.7 4.2 3.6 2.1 2.3 2.4 2.4 1.9 3.2 1.7 2.7 3.0 6.1 4.6 3.5 3.9 4.5 3.8 3.8 3.1 2.9 0.9 3.4 3.8 3.5 3.2 1.7 2.3 2.1 2.6 3.8 2.6 3.2 2.9 3.7 3.7 2.9 4.2 2.2 8.0 1.3 2.9 3.2 1.0 5.7 2.8 4.7 2.9 2.9 12.1 2.9 2.5 5.0 3.3 2.4 1.7 9.1 5.2 1.9 3.8 4.8 4.4 4.0 1.9 2.7 4.6 2.9 1.0 6.1 3.0 3.5 7.2 6.4 3.3 5.5 2.2 5.7 4.9 2.1 6.4 2.8 8.0 9.9 5.1 4.2 4.3 3.7 7.7 2.3 4.2 3.5 3.7 4.5 3.2 9.2 2.0 2.2 0.4 4.0 5.5 3.3 2.7 4.8 8.5 8.4 2.5 4.0 4.1 5.2 4.4 2.3 6.4 2.8 3.6 5.7 5.2 2.1 6.5 5.6 7.1 6.1 8.0 5.9 2.3 9.6 5.9 3.5 3.0 4.9 6.5 7.4 8.0 4.3 3.1 4.3 4.1 3.4 2.7 3.0 4.5 3.8 3.8 2.9 4.2 5.7 41.2 16.0 33.2 24.2 55.5 12.4 41.6 20.2 29.6 42.0 17.1 17.8 33.6 50.1 33.8 16.5 58.4 33.4 55.8 40.3 11.7 18.3 96.6 24.2 33.6 40.5 45.4 45.5 12.1 20.3 23.0 49.0 53.0 23.7 29.1 65.4 88.2 50.4 37.9 50.5 20.5 33.0 22.4 38.1 22.5 21.9 123.0 35.8 7.2 34.7 44.5 32.4 74.2 24.1 39.1 15.2 30.6 83.8 51.7 33.6 30.8 26.2 23.5 70.5 65.7 76.6 45.7 104.5 64.1 25.4 13.4 40.8 54.4 59.7 32.8 28.7 DDIT4L "REDD2, Rtp801L" ENSG00000145358 "DNA damage inducible transcript 4 like" Q96D03 4 100185870-100190782 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "skeletal muscle: 323.5;tongue: 106.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 22.0;Distal tubular cells: 21.5;Extravillous trophoblasts: 18.5;Granulosa cells: 23.5;Sertoli cells: 19.7" "Cancer enhanced" "Detected in many" "testis cancer: 19.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 19.3;BJ: 29.6;fHDF/TERT166: 16.2;HSkMC: 14.7;hTERT-RPE1: 32.8;RPTEC TERT1: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050903 Uncertain "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane" "Nucleoplasm, Actin filaments" "HPA050903: " "unprognostic (2.21e-1)" "unprognostic (1.92e-1)" "unprognostic (1.34e-1)" "prognostic favorable (5.77e-4)" "unprognostic (1.66e-3)" "unprognostic (5.92e-2)" "unprognostic (2.72e-2)" "unprognostic (3.12e-1)" "unprognostic (3.21e-1)" "unprognostic (7.18e-2)" "unprognostic (2.59e-1)" "unprognostic (1.41e-1)" "unprognostic (4.47e-2)" "unprognostic (4.82e-3)" "unprognostic (2.09e-2)" "unprognostic (7.53e-5)" "unprognostic (4.99e-3)" 3.1 1.0 7.0 0.6 21.1 0.4 2.2 8.5 11.0 23.0 7.7 2.0 0.3 1.5 1.7 7.7 2.1 0.6 2.3 10.2 7.6 21.8 0.4 0.8 0.5 11.8 8.8 7.7 0.4 0.6 2.0 3.7 11.1 11.2 0.9 1.2 17.4 6.9 323.5 1.1 0.7 1.6 9.1 1.2 0.5 3.0 8.7 1.2 1.1 106.9 0.4 1.2 2.6 8.9 0.0 2.2 8.5 0.0 3.7 19.3 1.2 29.6 2.5 0.5 0.1 0.1 0.9 0.0 0.7 16.2 0.7 0.0 6.2 0.5 0.5 0.0 0.2 0.0 0.5 0.0 0.2 0.0 0.0 14.7 0.1 0.3 1.5 32.8 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 9.7 0.0 0.0 0.6 0.0 0.0 20.5 0.1 0.1 0.1 0.6 1.2 4.0 2.0 0.0 0.1 0.1 0.0 0.0 0.0 2.3 3.9 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 7.0 21.1 8.5 11.0 10.2 7.6 11.8 8.8 11.1 9.1 8.7 8.9 3.8 0.0 0.0 6.2 0.0 2.7 0.2 4.2 1.8 0.1 1.0 0.9 7.3 0.0 1.3 22.0 0.0 1.9 0.4 0.2 21.5 0.1 0.8 0.5 0.3 3.6 0.0 0.0 0.0 0.0 18.5 5.1 1.5 0.9 0.0 23.5 0.0 0.0 12.0 0.0 0.5 0.3 0.0 0.0 3.0 0.4 0.9 0.3 7.2 0.0 0.0 8.6 0.0 0.5 0.0 0.5 0.0 2.2 0.2 1.1 0.0 2.2 0.1 0.2 19.7 7.3 11.9 4.7 0.8 0.9 1.4 4.0 0.6 8.3 0.4 0.3 DDR2 "NTRKR3, TKT, TYRO10" ENSG00000162733 "Discoidin domain receptor tyrosine kinase 2" Q16832 1 162631373-162787405 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Osteogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 89.8;Fibroblasts: 116.5;Leydig cells: 63.0;Peritubular cells: 88.4;Skeletal myocytes: 98.2;Smooth muscle cells: 78.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 233.3;ASC TERT1: 214.4;BJ hTERT+: 163.4;fHDF/TERT166: 137.6;HSkMC: 157.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070112 Approved "Plasma membrane,Actin filaments" Yes No 770000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Actin filaments" "HPA070112: AB_2686229" "unprognostic (4.12e-2)" "unprognostic (2.73e-1)" "unprognostic (6.97e-3)" "unprognostic (4.52e-2)" "unprognostic (1.17e-1)" "unprognostic (8.16e-2)" "unprognostic (1.81e-1)" "unprognostic (1.19e-1)" "unprognostic (6.62e-2)" "unprognostic (2.24e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.73e-7)" "unprognostic (1.56e-3)" "unprognostic (8.26e-3)" "unprognostic (7.57e-2)" "unprognostic (4.10e-3)" 59.8 64.3 13.2 15.8 11.3 0.3 25.2 10.4 9.2 33.7 51.5 54.7 5.8 26.2 13.2 18.1 22.4 23.8 24.1 12.6 24.5 6.4 5.4 14.5 9.1 37.0 22.1 37.4 3.7 2.5 5.4 10.6 31.7 17.3 14.1 5.1 9.8 29.2 4.9 9.7 17.6 42.8 17.8 5.8 20.4 3.9 21.0 3.3 12.9 19.3 6.9 23.2 23.6 25.2 0.3 0.0 0.2 63.2 233.3 214.4 1.0 92.2 163.4 41.5 56.8 0.0 0.2 0.0 0.1 137.6 8.9 0.1 0.3 0.4 54.0 42.9 0.3 0.0 0.4 0.1 103.9 0.2 0.2 157.0 0.4 73.1 2.2 65.8 46.0 0.4 0.6 16.8 36.9 0.1 0.0 0.3 0.4 0.1 0.3 0.1 24.1 0.7 0.2 0.2 0.3 35.4 0.2 0.1 2.9 3.6 0.2 0.3 2.1 58.5 13.8 29.1 12.6 2.6 4.0 0.1 56.3 0.1 62.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 11.3 10.4 9.2 12.6 24.5 37.0 22.1 31.7 17.8 21.0 25.2 23.4 3.2 2.3 53.2 2.5 12.6 3.9 0.8 1.2 3.0 6.0 15.6 31.3 1.5 1.1 0.0 0.0 0.5 1.7 3.2 0.0 0.4 8.9 5.0 89.8 22.3 1.2 0.0 13.1 1.8 0.5 116.5 2.6 8.2 1.3 16.7 30.0 3.5 1.2 0.0 26.2 1.0 0.0 1.9 19.3 7.1 63.0 3.1 23.2 29.0 0.0 16.5 2.1 6.0 5.6 1.8 4.4 88.4 5.6 5.9 1.2 2.1 2.4 3.0 39.5 98.2 78.3 1.0 0.9 2.0 8.7 1.0 2.5 34.2 0.8 4.2 EFR3B "FLJ37871, KIAA0953" ENSG00000084710 "EFR3 homolog B" Q9Y2G0 2 25042076-25159135 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.1;skeletal muscle: 20.0" "Cell type enhanced" "Detected in many" "Astrocytes: 127.0;Excitatory neurons: 58.5;Inhibitory neurons: 110.7;Late spermatids: 46.0;Microglial cells: 54.4;Oligodendrocytes: 51.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.3" "Cell line enhanced" "Detected in many" "AN3-CA: 10.3;BEWO: 12.0;SH-SY5Y: 10.7;SK-BR-3: 18.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038089, HPA071831" Uncertain Supported "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 10: Brain - Neuronal signaling" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Actin filaments, Cytosol" "HPA038089: AB_10672618, HPA071831: " "unprognostic (9.31e-2)" "unprognostic (3.92e-1)" "unprognostic (2.10e-1)" "unprognostic (2.23e-1)" "unprognostic (1.90e-1)" "unprognostic (2.44e-2)" "unprognostic (1.24e-3)" "unprognostic (3.82e-1)" "unprognostic (3.42e-1)" "unprognostic (1.32e-2)" "unprognostic (4.49e-6)" "unprognostic (4.83e-2)" "unprognostic (4.43e-2)" "unprognostic (1.89e-1)" "unprognostic (2.46e-1)" "unprognostic (1.13e-1)" "unprognostic (1.55e-1)" 0.8 1.6 23.0 0.6 53.1 0.3 0.5 22.4 29.5 0.5 0.0 1.1 0.4 0.7 5.1 0.3 0.6 0.5 4.5 51.7 19.0 1.3 0.2 2.5 0.3 45.3 24.0 0.8 0.4 3.9 9.3 1.7 47.5 0.5 0.6 11.0 0.3 0.8 20.0 0.6 0.5 1.2 9.8 3.4 0.9 2.5 27.7 0.3 3.4 3.8 0.2 0.5 0.4 12.1 0.2 8.3 9.5 10.3 0.5 0.1 12.0 1.0 0.2 0.5 0.1 6.7 0.4 0.1 0.6 1.4 3.3 0.6 7.5 0.0 0.1 1.6 1.8 1.6 0.3 0.6 0.0 0.1 0.8 0.1 0.0 2.3 0.1 0.7 0.3 0.2 0.1 0.4 0.2 0.9 0.2 0.5 1.9 0.1 6.6 0.8 9.1 0.3 0.1 0.3 4.0 10.7 1.2 18.0 5.9 5.3 0.9 0.1 0.5 0.5 2.7 4.1 2.0 0.7 0.9 0.1 7.3 0.1 1.9 1.3 0.1 0.3 0.2 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.4 0.2 0.1 0.1 0.0 0.0 23.0 53.1 22.4 29.5 51.7 19.0 45.3 24.0 47.5 9.8 27.7 12.1 3.1 28.9 1.1 127.0 0.0 0.0 0.8 0.0 0.0 9.9 0.3 1.0 9.7 0.0 0.0 9.2 22.9 0.1 0.1 0.7 0.0 0.3 20.6 1.3 0.3 6.7 3.6 0.0 58.5 0.8 0.2 1.0 0.0 0.3 0.0 1.1 2.9 0.0 0.9 5.0 110.7 0.1 0.0 0.0 0.3 46.0 1.2 0.1 0.0 54.4 0.0 22.0 0.0 19.6 51.2 0.7 0.0 2.6 0.1 0.6 0.5 0.1 0.0 10.7 0.0 1.6 1.4 2.4 2.2 0.0 0.1 0.1 0.1 0.2 0.3 0.4 ERBB3 "HER3, LCCS2" ENSG00000065361 "Erb-b2 receptor tyrosine kinase 3" P21860 12 56076799-56103505 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 254.3;Oligodendrocytes: 187.0;Paneth cells: 184.6;Proximal enterocytes: 240.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 2.4;neutrophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.4" "Cell line enhanced" "Detected in many" "Hep G2: 116.4;OE19: 119.1;RT4: 89.7;SK-BR-3: 106.5;SK-MEL-30: 149.5;T-47d: 122.2;WM-115: 153.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025331, HPA045396, HPA070524" Approved Supported "Plasma membrane,Actin filaments" "Secreted - unknown location" NA NA 450000 "Cluster 17: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Actin filaments" "CAB025331: , HPA045396: AB_2679312, HPA070524: " "unprognostic (2.97e-1)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (8.97e-2)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (2.31e-3)" "unprognostic (2.66e-2)" "unprognostic (9.89e-2)" "unprognostic (4.30e-2)" "unprognostic (4.76e-3)" "unprognostic (5.77e-2)" "unprognostic (1.06e-2)" "unprognostic (4.56e-2)" "unprognostic (1.57e-1)" "unprognostic (6.72e-3)" "unprognostic (2.07e-2)" 2.4 2.6 34.4 8.0 69.2 0.9 56.5 45.9 62.0 20.9 10.9 62.9 88.5 5.5 12.3 82.0 12.1 30.6 9.0 39.2 43.1 36.2 98.6 29.3 0.6 59.4 54.4 1.6 57.0 23.8 2.4 13.0 54.7 37.8 64.1 1.3 83.0 18.2 2.4 75.7 82.5 3.8 36.2 0.6 74.7 2.3 55.9 1.0 9.4 1.7 12.5 21.8 44.2 104.9 39.8 2.1 3.2 1.4 0.2 0.1 63.2 3.9 7.2 4.5 4.1 20.4 70.4 0.2 0.8 1.0 0.6 32.2 5.0 7.7 2.3 0.7 3.0 0.1 1.1 116.4 0.1 0.1 0.5 1.3 9.3 0.7 0.3 0.7 0.1 0.8 2.6 1.0 0.4 71.6 0.4 1.3 10.4 119.1 1.9 0.4 7.4 2.1 7.9 89.7 3.3 1.3 2.6 106.5 149.5 9.1 122.2 0.7 0.3 0.5 4.0 1.9 0.5 0.9 0.6 0.6 0.4 0.3 153.4 2.4 0.1 0.3 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.4 1.0 0.4 0.2 0.2 0.3 0.1 34.4 69.2 45.9 62.0 39.2 43.1 59.4 54.4 54.7 36.2 55.9 104.9 0.8 118.6 81.0 1.0 1.5 18.2 15.3 21.6 19.4 1.5 106.4 47.8 1.9 171.6 74.6 35.0 2.1 52.6 2.0 254.3 1.9 60.1 1.3 36.1 10.9 2.7 93.1 2.7 0.7 88.1 84.6 4.5 96.4 95.9 1.3 0.7 5.0 112.0 6.1 0.0 2.0 145.2 40.7 1.9 3.7 0.5 1.5 1.5 55.2 1.0 1.7 7.7 0.0 49.8 187.0 94.8 184.6 0.0 0.3 103.3 240.2 30.0 54.8 1.1 6.6 4.5 3.4 9.5 13.4 87.7 36.9 100.6 2.5 0.1 136.9 135.4 ERVFRD-1 "envFRD, ERVFRDE1, HERV-FRD, HERV-W/FRD, syncytin-2" ENSG00000244476 "Endogenous retrovirus group FRD member 1, envelope" P60508 6 11102489-11111725 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "placenta: 37.0" "Cell type enriched" "Detected in some" 56 "Syncytiotrophoblasts: 575.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SuSa: 38.8" HPA011812 Uncertain "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Actin filaments" "Nucleoplasm, Cytosol" "HPA011812: AB_1857702" "unprognostic (1.99e-1)" "unprognostic (3.29e-4)" "unprognostic (4.75e-2)" "unprognostic (1.80e-1)" "unprognostic (1.34e-1)" "unprognostic (2.19e-3)" "unprognostic (3.35e-1)" "unprognostic (6.44e-2)" "unprognostic (1.24e-1)" "unprognostic (1.99e-1)" "unprognostic (1.30e-2)" "unprognostic (2.78e-3)" "unprognostic (5.80e-4)" "unprognostic (3.40e-2)" "unprognostic (1.82e-1)" "unprognostic (1.95e-2)" "unprognostic (1.37e-2)" 0.3 0.4 0.6 0.1 0.4 0.2 0.4 1.8 0.6 0.4 0.0 0.3 0.5 0.3 1.0 0.3 0.2 0.4 0.1 0.6 0.7 0.5 0.2 0.6 0.0 0.6 0.4 0.0 0.0 7.5 0.0 37.0 0.5 0.3 0.2 0.2 0.2 0.2 0.0 0.5 0.5 0.2 0.1 0.0 0.3 0.1 0.6 0.4 0.0 0.4 0.0 0.5 0.2 0.6 0.0 0.1 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 38.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.4 1.8 0.6 0.6 0.7 0.6 0.4 0.5 0.1 0.6 0.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.6 0.0 0.6 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.1 0.3 0.0 0.0 10.1 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.1 0.0 0.0 0.0 575.5 0.4 0.5 0.0 0.0 FCHSD2 "KIAA0769, SH3MD3" ENSG00000137478 "FCH and double SH3 domains 2" O94868 11 72836745-73142318 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 219.6;Microglial cells: 387.8;Oligodendrocyte precursor cells: 471.0;Oligodendrocytes: 198.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 164.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038545, HPA038546" Uncertain Approved "Nuclear speckles,Plasma membrane,Actin filaments,Focal adhesion sites" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Actin filaments" "Nuclear speckles, Focal adhesion sites" "HPA038545: AB_2676074, HPA038546: AB_10673013" "unprognostic (1.80e-2)" "unprognostic (1.50e-2)" "prognostic favorable (1.71e-4)" "unprognostic (1.63e-1)" "unprognostic (3.14e-2)" "unprognostic (2.62e-3)" "unprognostic (1.41e-2)" "unprognostic (2.62e-1)" "unprognostic (1.27e-2)" "unprognostic (2.56e-1)" "unprognostic (3.69e-2)" "unprognostic (6.16e-2)" "unprognostic (2.89e-3)" "unprognostic (2.02e-1)" "unprognostic (4.70e-1)" "unprognostic (2.92e-1)" "unprognostic (1.23e-1)" 22.2 19.2 43.3 33.4 47.9 28.6 16.8 31.5 38.7 14.9 34.6 14.5 8.9 16.0 6.9 11.7 13.8 22.6 25.5 37.0 44.5 13.0 17.6 23.9 45.2 36.6 36.4 32.3 10.4 9.9 8.1 31.2 35.4 11.6 14.4 19.6 9.3 13.8 8.8 9.0 17.7 17.2 32.5 42.3 13.1 22.6 41.3 28.5 14.9 14.7 46.1 21.6 11.7 45.0 14.2 12.3 26.0 31.3 9.8 23.9 21.8 26.7 50.6 14.8 12.0 9.6 21.0 76.3 31.3 31.0 15.6 20.0 15.3 14.1 21.0 27.2 7.0 64.2 14.3 33.4 25.7 30.6 7.6 14.6 15.6 15.1 17.7 33.4 35.7 26.7 13.7 49.6 19.5 16.1 36.4 54.7 5.5 15.6 13.8 56.4 39.8 164.1 24.8 21.4 13.1 16.9 9.6 16.2 31.9 12.2 12.4 23.7 47.9 45.9 18.5 32.9 7.5 46.8 29.4 71.2 8.4 51.4 13.8 18.3 8.4 18.7 2.8 5.1 1.9 22.2 2.8 3.2 8.1 26.9 3.2 4.1 19.9 2.0 3.0 32.3 3.2 3.6 43.3 47.9 31.5 38.7 37.0 44.5 36.6 36.4 35.4 32.5 41.3 45.0 47.3 9.6 14.0 114.9 76.7 8.5 5.2 3.6 9.1 13.5 5.9 4.7 16.0 8.6 6.1 3.7 25.0 12.4 39.4 1.9 1.9 4.1 6.2 6.6 8.3 30.2 4.8 19.4 79.4 6.2 9.2 9.4 7.7 5.4 2.5 33.6 46.1 11.3 19.9 10.1 219.6 7.7 4.1 30.8 29.9 10.0 10.8 32.8 5.4 387.8 20.6 10.6 5.2 471.0 198.1 5.3 5.7 16.6 70.1 3.8 1.8 3.5 3.9 17.0 6.6 13.0 26.1 9.6 13.0 7.1 5.8 12.0 14.9 6.0 3.7 4.8 FLT1 "FLT, VEGFR1" ENSG00000102755 "Fms related receptor tyrosine kinase 1" P17948 13 28300346-28495145 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "placenta: 432.4" "Cell type enhanced" "Detected in many" "Adipocytes: 411.6;Endothelial cells: 263.1;Extravillous trophoblasts: 815.4;Hepatic stellate cells: 234.9;Microglial cells: 433.8;Syncytiotrophoblasts: 1127.1" "Cancer enhanced" "Detected in all" "renal cancer: 28.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 71.8;BJ hTERT+: 57.2;HMC-1: 349.2;HUVEC TERT2: 64.9;WM-115: 127.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011740, HPA014290, CAB068189, CAB068190" Enhanced Supported "Plasma membrane,Actin filaments" "Secreted to blood" NA NA 876000 87000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "Actin filaments" "CAB068189: AB_2665636, CAB068190: AB_2665637, HPA011740: AB_1858737, HPA014290: AB_1858738" "unprognostic (3.33e-2)" "unprognostic (3.52e-3)" "unprognostic (1.13e-3)" "unprognostic (5.02e-2)" "unprognostic (3.65e-1)" "unprognostic (5.03e-2)" "unprognostic (8.25e-2)" "unprognostic (2.27e-3)" "unprognostic (9.91e-2)" "unprognostic (6.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.19e-4)" "unprognostic (4.20e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (6.32e-2)" 47.6 9.6 37.6 9.1 36.2 1.1 31.2 37.0 43.0 16.4 24.6 9.4 7.5 17.2 3.7 5.9 11.7 16.6 46.0 33.3 39.8 34.9 18.2 25.8 5.3 44.6 40.0 4.4 12.7 30.5 9.0 432.4 50.1 13.9 6.1 52.5 7.0 11.0 19.9 5.9 9.3 17.4 33.4 18.6 10.9 17.4 59.6 3.6 48.9 38.8 5.7 14.0 9.5 38.7 0.1 0.0 0.0 0.6 0.6 0.9 0.3 71.8 57.2 25.8 14.9 0.0 0.2 0.1 0.1 9.6 0.0 0.3 6.7 0.0 45.4 0.0 2.0 0.2 0.1 0.0 0.1 0.0 349.2 0.6 0.0 0.1 1.0 0.1 64.9 6.1 1.7 0.3 0.0 0.3 4.5 3.7 37.5 0.0 0.1 2.9 0.0 0.1 0.1 0.1 8.1 0.6 0.0 0.1 0.2 44.4 0.3 0.2 6.3 0.2 1.2 0.1 0.1 2.1 1.0 0.2 0.4 0.3 127.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 37.6 36.2 37.0 43.0 33.3 39.8 44.6 40.0 50.1 33.4 59.6 38.7 411.6 0.0 6.0 2.0 4.7 4.1 0.7 0.2 3.4 17.8 1.2 1.5 26.5 2.8 2.9 0.0 4.2 197.2 1.4 0.1 1.9 0.6 157.2 0.5 1.5 263.1 0.0 0.0 0.9 0.0 815.4 32.1 0.5 2.1 1.3 0.1 234.9 6.9 30.8 1.7 14.5 0.0 0.0 12.5 23.6 173.8 18.6 15.3 0.0 433.8 0.0 153.2 0.0 9.5 2.0 0.0 0.0 48.5 4.1 1.3 0.0 0.1 1.8 9.7 92.1 11.4 30.1 14.6 4.6 1.0 4.8 1127.1 2.8 1.5 0.0 1.1 GFRAL "bA360D14.1, C6orf144, GRAL, UNQ9356" ENSG00000187871 "GDNF family receptor alpha like" Q6UXV0 6 55327469-55402493 "Predicted membrane proteins" Receptor "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047372 Uncertain Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "Actin filaments, Focal adhesion sites" "HPA047372: AB_2680017" "unprognostic (2.31e-1)" 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.3 0.3 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GSC ENSG00000133937 "Goosecoid homeobox" P56915 14 94768223-94770113 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 3.8;breast: 6.8" "Cell type enhanced" "Detected in some" "Adipocytes: 3.5;Breast myoepithelial cells: 2.2;Ductal cells: 3.0;Exocrine glandular cells: 2.4;Fibroblasts: 9.2;Langerhans cells: 2.3;Skeletal myocytes: 2.6;Smooth muscle cells: 4.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 9 "hypothalamus: 1.4" "Immune cell enriched" "Detected in single" 8 "gdT-cell: 3.6" "Lineage enriched" "Detected in single" 18 "T-cells: 3.6" "Cell line enhanced" "Detected in some" "AN3-CA: 1.3;HEK 293: 2.0;MCF7: 3.2;REH: 3.3;SH-SY5Y: 3.5;T-47d: 2.5;U-251 MG: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB079923, CAB079924" Supported "Nucleoplasm,Nuclear speckles,Actin filaments" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: REH - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear speckles" "Actin filaments" "CAB079923: , CAB079924: " "unprognostic (2.11e-2)" "unprognostic (1.04e-1)" "unprognostic (3.15e-2)" "unprognostic (5.11e-2)" "unprognostic (2.49e-1)" "unprognostic (3.70e-3)" "unprognostic (1.82e-3)" "unprognostic (3.87e-2)" "unprognostic (3.41e-1)" "unprognostic (2.74e-1)" "unprognostic (1.39e-1)" "unprognostic (2.28e-1)" "unprognostic (5.18e-10)" "unprognostic (4.96e-2)" "unprognostic (1.31e-1)" "unprognostic (1.52e-1)" "unprognostic (1.16e-1)" 3.8 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.1 0.4 0.1 0.1 0.2 0.0 0.1 0.4 0.0 0.5 0.0 1.4 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.6 0.1 0.4 0.0 0.0 0.7 0.0 0.0 0.9 0.5 1.2 0.8 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.2 1.6 2.2 0.1 0.3 0.2 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.3 0.0 0.0 0.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 3.2 0.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.0 0.6 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.1 0.0 0.0 0.1 0.0 3.5 0.0 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.0 1.0 2.2 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 3.0 0.1 0.3 0.1 0.4 0.0 0.0 0.0 2.4 0.0 9.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.2 0.0 0.0 0.6 0.0 1.0 0.0 0.0 0.7 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 2.6 4.6 0.0 1.2 0.0 0.9 0.0 0.4 0.0 0.0 0.1 H1-0 "H1.0, H1F0, H1FV" ENSG00000189060 "H1.0 linker histone" P07305 22 37805093-37807436 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 660.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 51.4;Cytotrophoblasts: 42.9;Extravillous trophoblasts: 125.7;Hofbauer cells: 73.2;Syncytiotrophoblasts: 219.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 8.1;granulocytes: 17.1;monocytes: 11.7" "Cell line enhanced" "Detected in many" "OE19: 662.8;U-2 OS: 823.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000843 Supported Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus,Actin filaments" Yes No 120000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nuclear bodies" "Golgi apparatus, Actin filaments" "HPA000843: AB_1079062" "unprognostic (1.29e-2)" "unprognostic (1.68e-1)" "unprognostic (1.69e-2)" "unprognostic (1.27e-1)" "unprognostic (3.31e-3)" "unprognostic (1.19e-1)" "unprognostic (2.18e-1)" "unprognostic (3.85e-1)" "unprognostic (7.68e-2)" "unprognostic (1.86e-1)" "unprognostic (5.95e-3)" "unprognostic (4.86e-3)" "prognostic favorable (7.68e-7)" "unprognostic (3.40e-1)" "unprognostic (1.47e-1)" "unprognostic (1.37e-3)" "unprognostic (1.73e-1)" 89.8 53.5 56.6 36.7 55.4 660.5 121.4 72.5 64.1 218.3 42.5 146.2 129.9 168.2 43.5 230.6 119.7 56.3 86.5 55.4 67.1 292.8 179.3 72.4 24.4 58.4 54.2 120.7 125.9 93.2 58.2 80.0 57.7 151.7 120.0 39.9 155.3 40.2 216.2 228.6 137.1 97.7 52.6 36.7 131.2 42.4 58.3 136.2 93.9 93.5 46.6 85.6 194.9 55.8 159.6 67.9 206.0 91.8 53.4 48.4 291.6 126.9 262.3 362.6 512.6 278.1 247.3 0.2 31.1 106.3 84.1 303.8 0.0 87.2 256.0 0.9 15.3 268.2 25.3 187.4 185.8 0.1 0.7 45.4 152.4 182.3 203.2 4.0 97.8 60.4 0.1 0.5 28.5 263.3 45.4 26.5 80.2 662.8 329.9 74.6 122.6 56.1 58.0 42.7 47.3 263.9 349.9 235.4 473.9 91.8 184.2 167.1 65.4 27.4 823.3 122.7 25.9 0.7 18.5 1.2 33.5 95.9 80.3 17.1 9.9 15.7 0.1 11.7 0.1 0.0 1.0 0.2 8.1 0.1 2.8 0.4 5.4 0.1 10.3 7.4 0.2 6.9 56.6 55.4 72.5 64.1 55.4 67.1 58.4 54.2 57.7 52.6 58.3 55.8 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.4 0.0 0.0 0.0 0.0 42.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 125.7 25.2 0.0 0.0 0.0 0.0 0.0 0.0 73.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 219.7 0.0 0.0 0.0 0.0 ICOS "AILIM, CD278" ENSG00000163600 "Inducible T cell costimulator" Q9Y6W8 2 203936763-203961577 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "bone marrow: 16.5;lymphoid tissue: 20.2" "Cell type enriched" "Detected in some" 12 "T-cells: 81.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 29.1" "Lineage enriched" "Detected in single" 54 "T-cells: 29.1" "Group enriched" "Detected in some" 8 "HEL: 4.6;MOLT-4: 12.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB032575, HPA034865" Approved Approved "Plasma membrane,Actin filaments" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Actin filaments" "CAB032575: AB_2122593, HPA034865: " "unprognostic (2.66e-2)" "unprognostic (2.13e-3)" "unprognostic (4.19e-4)" "unprognostic (2.35e-5)" "unprognostic (1.07e-1)" "prognostic favorable (1.80e-4)" "unprognostic (9.38e-2)" "unprognostic (2.89e-2)" "unprognostic (1.49e-2)" "unprognostic (3.51e-4)" "unprognostic (7.50e-2)" "unprognostic (2.12e-1)" "unprognostic (2.86e-5)" "unprognostic (7.05e-2)" "unprognostic (2.48e-2)" "unprognostic (1.93e-1)" "unprognostic (8.82e-3)" 0.5 0.1 0.0 7.7 0.0 16.5 0.3 0.0 0.0 0.2 0.0 0.7 0.7 0.2 0.1 0.5 0.3 1.4 0.2 0.0 0.0 0.2 0.4 2.6 14.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.5 1.3 0.0 0.4 0.0 0.0 0.2 2.3 0.4 0.0 3.3 1.3 0.2 0.0 20.2 0.4 0.0 16.2 2.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 4.2 0.0 15.1 6.8 0.0 0.0 15.7 7.2 0.1 0.5 0.0 0.0 29.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.3 0.0 3.1 2.9 0.0 0.0 0.0 0.0 1.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.1 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 1.1 2.0 0.2 6.3 0.0 0.4 0.1 0.1 0.0 0.0 0.2 0.0 0.8 4.7 0.1 0.0 3.1 3.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.3 0.0 1.8 0.1 81.2 0.0 0.0 0.1 LMOD2 ENSG00000170807 "Leiomodin 2" Q6P5Q4 7 123655866-123664290 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 39 "heart muscle: 778.4;skeletal muscle: 933.7;tongue: 793.6" "Cell type enriched" "Detected in some" 26 "Cardiomyocytes: 1432.4" "Group enriched" "Detected in some" 20 "head and neck cancer: 3.5;prostate cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HSkMC: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA046370, HPA051039" Enhanced Uncertain "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Actin filaments, Cytosol" "HPA046370: , HPA051039: AB_2681321" "unprognostic (2.55e-1)" "unprognostic (1.14e-1)" "unprognostic (1.43e-1)" "unprognostic (2.38e-3)" "unprognostic (1.18e-1)" "unprognostic (5.50e-1)" "unprognostic (5.69e-2)" "unprognostic (6.98e-2)" "unprognostic (2.13e-2)" "unprognostic (1.43e-3)" "unprognostic (3.37e-2)" "unprognostic (1.51e-1)" "unprognostic (1.82e-3)" 0.2 0.1 0.0 0.0 0.0 0.6 0.5 0.1 0.5 0.0 0.2 0.1 0.0 0.0 0.0 21.2 0.0 0.1 778.4 0.2 0.0 0.0 0.2 0.3 0.3 0.0 0.1 0.1 0.2 0.0 0.1 0.8 0.0 10.2 0.0 0.1 10.0 0.0 933.7 0.4 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.2 793.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1432.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.4 0.5 0.4 9.4 0.0 0.0 0.1 0.0 0.1 27.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.9 7.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 LYZ ENSG00000090382 Lysozyme P61626 12 69348381-69354234 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase" "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 10588.1;salivary gland: 21115.5;stomach 1: 8941.1" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 3106.1;Kupffer cells: 2841.2;Langerhans cells: 4859.1;Macrophages: 4870.7;monocytes: 7063.0;Pancreatic endocrine cells: 3152.5" "Cancer enhanced" "Detected in all" "stomach cancer: 976.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 25266.2;myeloid DC: 14438.7" "Group enriched" "Detected in all" 20 "dendritic cells: 14438.7;monocytes: 25266.2" "Cell line enriched" "Detected in many" 13 "OE19: 12130.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000055, HPA048284, HPA066182" Enhanced Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" NA NA 1500000000 1500000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus, Actin filaments" Nucleoplasm "CAB000055: AB_2341230, HPA048284: AB_2680339, HPA066182: AB_2732741" "unprognostic (8.52e-2)" "unprognostic (6.12e-3)" "unprognostic (2.83e-1)" "unprognostic (7.29e-2)" "unprognostic (7.91e-2)" "prognostic favorable (7.45e-4)" "unprognostic (1.21e-1)" "unprognostic (7.40e-2)" "unprognostic (1.41e-1)" "unprognostic (2.08e-2)" "unprognostic (1.44e-1)" "unprognostic (3.13e-1)" "unprognostic (2.50e-1)" "unprognostic (2.37e-1)" "unprognostic (3.65e-2)" "unprognostic (5.78e-2)" "unprognostic (3.62e-2)" 95.8 27.8 3.5 802.1 4.0 10588.1 128.2 3.7 18.5 156.2 11.4 309.0 3605.0 65.7 4.2 106.3 33.9 1054.6 34.8 2.6 4.3 32.4 138.0 1355.2 739.7 8.0 7.3 20.4 63.1 13.8 7.2 91.3 12.2 40.2 273.8 4.4 21115.5 21.8 34.0 58.7 1322.2 123.9 5.4 621.0 8941.1 21.8 10.9 321.8 27.8 36.4 652.8 428.5 16.2 11.7 0.6 0.1 0.0 0.2 0.0 0.0 4.8 0.0 0.0 0.0 0.3 9.5 6.5 4.2 1.5 0.0 3.6 1.2 0.0 0.0 0.2 1.2 0.1 62.4 1.0 960.4 0.0 110.6 50.5 0.0 0.1 0.0 0.0 0.2 0.0 0.3 7.7 0.3 0.0 0.2 2.6 109.5 2.3 12130.8 0.2 1.6 1.4 16.7 0.3 0.5 0.8 3.6 0.5 0.1 0.5 0.7 0.0 489.0 0.6 0.0 2.6 2.3 0.9 2.6 1.1 1.2 0.1 518.5 0.0 443.4 25266.2 298.2 32.6 4798.4 52.3 100.5 20.1 22.7 14438.7 20.8 20.0 17.8 1007.7 108.1 880.1 301.2 31.1 25392.1 3.5 4.0 3.7 18.5 2.6 4.3 8.0 7.3 12.2 5.4 10.9 11.7 24.0 86.6 285.8 0.0 80.8 57.2 1.7 1.2 1.2 0.3 1205.7 32.3 0.2 734.9 51.1 27.6 0.0 5.6 39.6 32.1 0.0 55.1 1.9 2.6 1.9 25.1 12.5 264.6 0.2 547.3 9.4 26.8 3106.1 2.9 123.6 0.5 29.6 25.4 887.1 0.0 0.2 112.4 0.0 2841.2 4859.1 17.4 4.1 4870.7 53.4 0.0 7063.0 0.1 176.1 0.0 0.3 3152.5 600.5 2.2 9.0 2.7 41.8 6.6 33.8 1.0 39.5 7.4 9.9 0.7 3.9 1.5 38.2 8.5 50.6 0.3 111.4 38.3 MSRA ENSG00000175806 "Methionine sulfoxide reductase A" Q9UJ68 8 10054292-10428891 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 86.0;liver: 64.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 625.8;Inhibitory neurons: 318.6;Oligodendrocyte precursor cells: 268.9;Proximal tubular cells: 666.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 5 "cerebellum: 28.4" "Immune cell enhanced" "Detected in some" "eosinophil: 5.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 12.3" "Low region specificity" "Detected in all" "HPA023804, HPA075766" Approved Supported "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" No No 55000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cytosol" "Plasma membrane, Actin filaments" "HPA023804: AB_1853826, HPA075766: " "unprognostic (1.55e-1)" "unprognostic (4.30e-3)" "unprognostic (1.45e-3)" "unprognostic (1.00e-2)" "unprognostic (4.21e-2)" "unprognostic (1.62e-2)" "unprognostic (1.49e-2)" "unprognostic (6.40e-2)" "unprognostic (9.69e-2)" "unprognostic (1.08e-1)" "unprognostic (1.80e-1)" "unprognostic (4.58e-2)" "unprognostic (1.07e-3)" "unprognostic (6.43e-3)" "unprognostic (4.02e-1)" "unprognostic (6.36e-3)" "unprognostic (3.07e-1)" 17.0 20.4 2.2 1.1 3.0 13.5 16.1 28.4 5.4 9.1 0.0 13.9 1.1 10.7 0.1 11.6 7.4 0.4 29.0 3.8 0.0 86.0 64.0 12.2 0.6 0.0 0.4 6.4 14.5 0.7 9.2 0.8 1.8 9.2 0.6 0.6 10.5 1.0 14.5 9.5 20.1 0.8 0.0 18.6 14.2 15.2 0.3 1.5 9.6 1.3 0.6 11.6 8.2 2.8 0.1 0.9 1.3 4.3 1.2 1.4 0.5 2.5 0.2 0.3 1.7 0.6 2.1 0.0 0.6 2.5 5.8 2.3 0.4 0.1 1.3 0.2 0.0 0.3 1.5 2.2 4.3 0.8 12.3 0.4 3.2 0.3 0.0 1.4 0.6 0.3 0.4 0.2 4.9 0.1 0.0 0.3 0.6 3.3 0.8 1.6 1.3 2.0 1.1 1.1 2.5 1.5 4.6 0.2 0.5 0.4 2.3 2.8 2.6 1.7 2.0 0.4 1.2 0.2 0.1 0.7 4.8 0.8 3.1 0.5 1.9 5.6 0.4 1.2 0.3 0.6 0.4 0.3 1.2 0.1 0.3 0.2 2.2 0.7 0.9 0.2 0.3 0.2 2.2 3.0 28.4 5.4 3.8 0.0 0.0 0.4 1.8 0.0 0.3 2.8 44.1 0.0 7.4 152.8 21.4 16.4 29.3 10.8 14.2 10.1 21.2 21.8 21.6 25.8 7.2 25.8 31.3 7.7 12.4 26.4 92.0 32.3 80.6 13.6 8.7 30.3 9.6 3.4 625.8 47.1 4.6 13.1 14.8 11.8 80.7 13.7 19.6 97.2 47.0 16.8 318.6 20.8 4.1 33.6 48.3 167.9 9.3 38.0 30.2 85.3 22.3 14.6 11.3 268.9 60.7 51.1 37.8 9.8 16.2 33.8 195.5 666.1 5.6 6.2 13.1 11.3 16.9 39.3 26.5 20.1 14.1 8.3 18.0 14.1 24.5 31.1 NAA60 "FLJ14154, NAT15" ENSG00000122390 "N-alpha-acetyltransferase 60, NatF catalytic subunit" Q9H7X0 16 3443649-3486953 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Chromosome partition" "Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040916 Approved Uncertain "Actin filaments,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" "Actin filaments, Cytosol" "HPA040916: AB_10794428" "unprognostic (8.59e-2)" "unprognostic (2.16e-3)" "unprognostic (3.39e-1)" "prognostic favorable (3.14e-4)" "unprognostic (1.81e-1)" "unprognostic (5.90e-2)" "unprognostic (2.88e-2)" "unprognostic (1.53e-2)" "unprognostic (5.23e-2)" "unprognostic (5.12e-2)" "prognostic favorable (4.30e-4)" "unprognostic (9.54e-2)" "unprognostic (1.64e-1)" "unprognostic (1.60e-2)" "unprognostic (8.96e-2)" "unprognostic (3.59e-1)" "unprognostic (6.74e-3)" 25.5 45.4 31.5 16.9 30.0 20.1 25.1 37.5 35.9 28.4 22.7 40.4 40.5 31.6 18.7 31.0 28.2 20.3 48.9 31.9 27.5 52.4 67.5 32.0 20.2 30.8 30.5 26.8 47.9 49.1 41.6 19.5 29.3 35.2 22.6 16.3 26.0 23.9 42.9 24.2 39.3 19.1 28.8 42.9 58.9 32.7 31.2 19.5 32.0 21.2 16.7 28.4 23.2 30.3 16.8 61.9 40.1 44.1 26.5 19.4 39.1 26.9 25.0 29.3 26.6 43.9 30.5 31.7 30.0 29.6 21.0 37.4 40.1 31.2 29.4 49.7 27.8 35.4 25.7 53.0 32.9 53.1 45.6 24.4 27.9 20.4 38.9 29.2 45.1 29.4 44.8 41.4 19.4 73.6 33.4 36.3 50.1 35.8 18.1 42.3 30.8 47.5 27.7 29.7 21.6 42.5 45.8 48.3 24.6 38.5 40.2 34.7 30.8 36.0 27.7 12.8 26.7 35.2 33.6 30.5 12.1 29.0 29.2 33.3 18.6 53.8 17.7 20.6 19.2 11.6 15.8 17.7 18.1 11.0 12.3 16.4 20.0 18.4 23.6 11.6 20.1 19.5 31.5 30.0 37.5 35.9 31.9 27.5 30.8 30.5 29.3 28.8 31.2 30.3 26.3 9.6 16.0 24.8 17.7 0.1 13.4 0.1 17.6 21.2 24.5 16.4 15.5 38.6 5.6 12.9 6.2 28.3 22.7 66.7 43.0 30.1 55.7 33.3 25.7 21.0 27.0 18.7 22.2 41.7 40.0 18.0 37.2 30.9 30.4 18.4 26.7 53.5 32.1 11.8 26.5 43.1 0.0 34.8 0.3 54.4 11.5 23.6 0.0 25.3 27.0 29.3 26.8 22.1 34.8 37.0 54.3 15.8 15.4 20.2 84.2 49.0 3.7 15.3 26.3 16.8 17.7 19.6 24.5 16.5 0.3 33.0 22.9 21.1 35.3 23.5 NDC1 "FLJ10407, NET3, TMEM48" ENSG00000058804 "NDC1 transmembrane nucleoporin" Q9BTX1 1 53765478-53838463 "Metabolic proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069751, HPA070882" Approved Supported "Nuclear membrane,Plasma membrane,Actin filaments" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear membrane" "Plasma membrane, Actin filaments" "HPA069751: AB_2686189, HPA070882: AB_2686320" "unprognostic (2.51e-1)" "unprognostic (1.93e-1)" "prognostic favorable (4.48e-5)" "unprognostic (6.96e-3)" "unprognostic (1.31e-1)" "unprognostic (1.36e-3)" "prognostic unfavorable (7.52e-7)" "unprognostic (3.46e-3)" "unprognostic (1.53e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (3.58e-4)" "unprognostic (9.27e-2)" "unprognostic (6.22e-3)" "unprognostic (3.00e-3)" "unprognostic (4.38e-2)" "unprognostic (9.24e-2)" "unprognostic (6.07e-2)" 5.4 5.2 3.4 9.5 3.5 8.4 11.1 3.6 4.1 5.7 3.6 11.9 8.9 6.5 7.4 7.7 7.5 4.6 4.5 3.6 3.4 6.9 7.8 4.7 15.7 3.2 3.3 5.9 4.7 9.5 1.7 8.0 3.3 4.8 14.2 6.0 4.2 5.2 4.3 7.3 8.2 7.1 3.5 5.6 6.4 7.5 3.5 14.2 6.8 5.2 18.4 7.1 4.2 3.9 61.6 31.2 42.8 43.7 15.5 15.5 49.3 40.9 31.0 63.8 51.1 47.5 40.4 119.0 26.2 18.6 51.2 72.0 73.2 43.3 89.8 29.8 50.9 58.5 42.9 40.5 14.3 95.3 31.9 9.4 17.0 62.9 37.5 18.6 39.1 44.2 67.7 16.9 35.6 22.2 47.2 38.2 101.0 52.2 49.9 52.0 68.4 66.0 29.8 41.7 25.4 32.2 36.5 71.5 35.9 45.3 55.3 50.2 22.7 32.9 32.6 45.5 74.9 17.9 48.8 84.7 27.3 71.6 42.2 0.0 2.3 1.5 3.0 5.0 4.7 3.6 2.8 2.7 2.6 2.8 5.3 4.1 0.1 3.1 3.3 2.3 3.4 2.4 3.4 3.5 3.6 4.1 3.6 3.4 3.2 3.3 3.3 3.5 3.5 3.9 4.4 6.4 6.3 12.4 8.7 10.1 6.4 9.0 12.0 4.5 10.1 6.3 8.1 4.3 5.4 5.5 2.1 11.5 5.9 7.9 0.0 8.5 2.3 5.0 5.6 6.1 0.0 19.4 13.8 9.1 20.2 6.3 8.6 4.6 7.6 21.5 5.3 7.1 11.8 3.3 11.0 10.3 16.2 8.2 8.9 2.1 2.8 7.1 7.2 13.1 4.7 3.3 3.1 11.6 19.4 7.0 5.8 3.4 20.1 8.9 2.9 4.5 5.5 2.9 6.6 6.3 15.7 11.8 14.3 18.2 8.5 6.8 6.7 4.3 18.2 6.5 NEURL1B "DKFZP761M1511, Neur2, RNF67B" ENSG00000214357 "Neuralized E3 ubiquitin protein ligase 1B" A8MQ27 5 172641263-172691540 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 82.8;Distal enterocytes: 82.5;Endothelial cells: 53.8;Leydig cells: 54.7;Paneth cells: 42.1;Proximal enterocytes: 53.4;Smooth muscle cells: 58.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "REH: 43.7;T-47d: 20.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037612 Approved Supported "Actin filaments,Cytosol" NA Yes "Cluster 46: Fibroblasts - ECM organization" "Cluster 14: REH - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Actin filaments" "HPA037612: AB_10795573" "unprognostic (3.56e-2)" "unprognostic (8.46e-2)" "unprognostic (6.72e-3)" "unprognostic (2.70e-1)" "unprognostic (1.64e-1)" "unprognostic (1.55e-1)" "unprognostic (6.58e-2)" "unprognostic (2.95e-1)" "unprognostic (2.86e-1)" "unprognostic (1.09e-1)" "unprognostic (7.13e-3)" "unprognostic (6.81e-2)" "prognostic unfavorable (3.00e-6)" "unprognostic (1.79e-1)" "unprognostic (1.40e-1)" "unprognostic (4.67e-2)" "unprognostic (3.22e-3)" 25.0 16.0 8.4 5.2 10.3 2.0 21.1 2.3 24.1 18.3 3.4 28.4 6.9 24.7 24.1 13.5 22.0 11.7 32.2 17.1 6.9 11.0 6.0 12.6 3.7 3.5 4.6 14.7 5.3 3.2 8.2 6.1 3.8 17.6 13.7 0.3 6.6 32.1 14.0 18.1 17.6 20.4 3.6 0.7 7.7 4.3 6.3 5.9 10.3 16.0 3.9 25.7 17.3 6.5 7.2 3.7 2.0 8.9 0.6 0.3 0.1 8.0 3.5 4.1 6.0 13.7 3.2 0.0 2.1 5.2 5.0 2.1 0.7 3.6 2.8 13.2 0.5 9.8 13.3 0.1 0.6 0.0 2.9 0.0 15.1 0.9 4.1 1.2 0.6 1.4 0.0 3.0 8.9 8.0 2.3 0.2 1.3 3.1 0.3 43.7 9.4 1.4 0.1 1.6 1.6 8.9 7.6 11.9 0.3 3.5 20.0 1.5 1.3 3.1 18.1 2.2 5.1 1.2 0.4 0.0 9.0 0.2 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 10.3 2.3 24.1 17.1 6.9 3.5 4.6 3.8 3.6 6.3 6.5 82.8 0.0 1.9 0.3 0.6 4.8 0.7 3.0 0.6 0.6 1.5 1.3 9.3 1.5 4.8 0.0 0.0 0.3 0.4 82.5 0.0 0.7 2.6 1.9 2.5 53.8 13.9 11.4 5.2 0.7 0.2 10.3 2.0 0.6 0.0 4.9 30.4 0.3 0.3 0.0 1.0 10.2 2.0 1.9 2.6 6.6 54.7 2.2 7.2 4.7 0.7 0.7 0.0 5.0 13.0 4.5 42.1 12.4 0.1 1.9 53.4 0.8 12.8 0.3 26.3 11.6 58.8 2.5 3.4 7.7 5.4 0.1 0.7 2.5 20.0 1.2 NTN1 NTN1L ENSG00000065320 "Netrin 1" O95631 17 9021510-9244000 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.1;heart muscle: 59.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 137.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 27.5;T-47d: 16.6;U-2 OS: 14.4;U-251 MG: 22.1;WM-115: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056419 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" "Secreted to extracellular matrix" NA NA 110000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "Nucleoplasm, Actin filaments" "HPA056419: AB_2683124" "unprognostic (2.72e-1)" "unprognostic (2.59e-2)" "unprognostic (7.12e-2)" "unprognostic (5.25e-2)" "unprognostic (2.51e-1)" "unprognostic (9.33e-3)" "unprognostic (9.42e-2)" "unprognostic (2.20e-1)" "unprognostic (1.63e-1)" "unprognostic (1.33e-2)" "unprognostic (1.89e-1)" "unprognostic (1.15e-1)" "unprognostic (2.49e-2)" "unprognostic (2.20e-2)" "unprognostic (2.60e-1)" "unprognostic (6.07e-3)" "unprognostic (8.31e-3)" 6.4 0.5 4.5 3.6 6.4 0.1 5.3 10.1 4.9 9.3 2.8 14.7 6.7 9.6 3.5 18.9 10.3 7.3 59.4 3.8 7.0 2.0 6.9 4.3 0.2 12.7 37.1 0.9 2.3 4.3 3.0 0.9 14.4 3.9 3.9 0.4 10.9 2.0 2.1 8.1 10.5 6.0 13.8 0.1 17.5 3.1 10.1 2.9 2.0 2.6 2.1 10.2 5.4 8.8 0.1 0.0 1.3 4.6 4.2 0.1 27.5 0.3 0.4 0.3 0.5 0.1 5.7 0.0 6.2 0.0 9.0 0.1 1.2 0.9 0.0 6.4 10.4 1.4 0.0 0.0 0.1 0.5 0.1 0.1 2.1 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.1 5.6 0.1 0.6 1.8 0.0 0.0 3.4 4.8 0.0 0.0 0.3 0.0 0.0 0.1 4.7 1.1 4.5 16.6 0.3 0.0 6.7 14.4 0.0 22.1 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 6.4 10.1 4.9 3.8 7.0 12.7 37.1 14.4 13.8 10.1 8.8 0.7 0.0 0.0 10.7 0.3 3.3 6.6 21.8 9.6 2.9 4.7 4.4 28.1 0.0 23.9 1.8 0.0 0.3 0.2 0.5 0.0 3.1 9.3 5.8 2.0 3.1 0.0 0.0 4.8 1.7 1.2 9.7 1.1 7.9 0.0 0.0 2.2 12.4 0.1 0.0 7.1 1.4 24.4 0.6 5.9 4.6 0.3 0.1 1.8 9.4 0.6 0.3 0.0 137.2 1.0 1.4 0.1 0.0 0.0 4.0 0.7 0.2 11.1 0.2 0.0 3.9 6.8 1.6 2.0 12.7 2.8 0.5 0.5 0.0 0.6 3.5 POU6F1 "BRN5, MPOU, TCFB1" ENSG00000184271 "POU class 6 homeobox 1" 12 51186936-51217708 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 20.9;Excitatory neurons: 22.2;Inhibitory neurons: 29.4;Oligodendrocyte precursor cells: 21.1;Oligodendrocytes: 23.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 6.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 4.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047021, HPA050411" Enhanced Supported "Nuclear bodies,Actin filaments" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear bodies" "Actin filaments" "HPA047021: AB_2679905, HPA050411: AB_2681119" "unprognostic (4.96e-2)" "unprognostic (1.08e-1)" "unprognostic (1.48e-3)" "unprognostic (1.45e-2)" "unprognostic (2.72e-1)" "unprognostic (6.58e-2)" "unprognostic (9.70e-2)" "unprognostic (7.11e-3)" "unprognostic (4.45e-1)" "unprognostic (2.05e-1)" "prognostic favorable (6.61e-4)" "unprognostic (2.48e-2)" "unprognostic (9.36e-2)" "unprognostic (2.09e-3)" "unprognostic (1.74e-1)" "unprognostic (2.02e-1)" "unprognostic (2.33e-1)" 2.0 1.5 0.3 1.2 1.3 0.4 1.7 3.6 6.0 3.1 0.0 2.4 0.6 2.5 0.1 0.7 2.2 1.2 1.1 1.4 0.0 1.2 0.5 1.8 0.8 0.0 0.0 3.2 1.3 0.8 2.6 0.6 0.0 2.1 0.2 1.3 2.1 1.4 4.0 1.4 1.5 1.5 0.0 1.5 1.3 0.3 0.3 0.2 2.3 1.3 0.5 1.7 1.7 0.0 0.3 0.8 1.0 1.4 0.3 1.2 0.5 0.5 0.6 0.6 0.7 0.1 0.5 1.8 0.2 0.4 0.3 0.0 1.2 0.0 0.0 2.8 1.8 0.5 1.1 0.0 1.0 0.4 2.4 0.6 0.5 1.0 0.1 1.4 2.0 0.7 0.7 4.9 0.3 0.0 0.2 0.7 1.8 0.0 0.0 0.5 0.6 0.0 0.3 0.0 1.3 2.2 1.2 0.0 2.3 0.5 0.5 1.7 1.5 1.1 0.9 0.3 1.3 3.2 2.8 0.2 1.0 0.4 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 3.6 6.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 4.5 6.4 2.8 20.9 2.1 3.1 1.3 0.4 0.0 10.0 2.3 1.3 3.1 1.5 1.7 7.3 4.2 0.6 1.1 0.1 1.9 0.8 5.3 0.9 1.7 4.8 0.0 2.7 22.2 2.0 0.2 3.2 0.5 1.6 5.1 2.4 3.6 1.2 0.3 1.7 29.4 0.3 4.1 2.2 3.9 3.7 5.9 1.1 1.8 8.4 1.7 3.7 0.0 21.1 23.6 1.6 0.2 6.8 0.7 1.8 0.0 0.7 2.7 7.9 0.0 3.8 4.1 0.1 0.7 0.5 2.8 0.4 1.8 0.2 0.6 0.7 PTPN11 "BPTP3, NS1, PTP2C, SH-PTP2, SHP-2, SHP2" ENSG00000179295 "Protein tyrosine phosphatase non-receptor type 11" Q06124 12 112418351-112509918 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005377 Approved Supported "Nucleoplasm,Nucleoli rim,Actin filaments,Cytosol" NA NA 74000 "Cluster 6: Non-specific - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Nucleoli rim" "Actin filaments, Cytosol" "CAB005377: AB_632401" "unprognostic (2.18e-3)" "unprognostic (1.73e-3)" "unprognostic (5.62e-2)" "unprognostic (1.19e-1)" "unprognostic (1.63e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "unprognostic (4.25e-2)" "unprognostic (3.55e-2)" "unprognostic (1.88e-1)" "unprognostic (2.22e-2)" "unprognostic (8.85e-2)" "unprognostic (3.75e-3)" "unprognostic (1.66e-1)" "unprognostic (2.46e-1)" "unprognostic (3.62e-2)" "unprognostic (1.80e-2)" 62.9 36.6 74.6 34.7 91.7 46.3 37.6 72.7 115.7 37.9 38.4 32.5 27.6 37.8 28.7 38.9 24.3 29.4 68.7 66.1 85.6 39.7 53.0 34.4 35.6 79.0 84.1 26.2 31.6 53.4 16.1 38.0 85.7 35.2 30.6 51.8 25.9 42.4 75.1 32.1 26.1 45.7 83.4 26.7 30.4 18.2 81.7 35.5 46.8 64.0 32.5 40.1 23.5 106.3 116.9 107.6 77.0 73.4 109.7 106.1 92.7 136.4 148.2 105.5 78.5 107.7 43.4 124.5 69.4 127.4 66.7 68.1 100.1 121.6 173.8 93.1 85.0 181.5 102.6 59.8 109.2 145.8 108.0 86.6 119.6 113.6 159.8 101.3 88.7 92.0 140.2 41.3 103.3 83.2 101.0 69.7 94.1 112.3 73.4 102.4 114.6 70.5 97.3 126.7 53.3 66.1 133.7 99.8 85.2 77.6 114.8 97.8 108.1 122.9 110.0 74.2 121.8 79.4 141.6 120.2 102.2 99.7 117.7 32.2 11.7 16.8 14.8 10.2 14.0 18.1 13.3 12.4 13.6 20.8 15.3 11.9 10.7 12.6 13.7 18.3 10.9 7.2 74.6 91.7 72.7 115.7 66.1 85.6 79.0 84.1 85.7 83.4 81.7 106.3 49.0 60.9 68.2 27.7 25.8 25.6 39.9 25.3 20.5 29.9 40.5 32.4 131.6 24.3 41.8 36.8 16.7 23.5 34.2 25.4 33.2 37.5 63.1 31.3 92.6 46.2 13.1 21.7 67.6 42.8 25.3 35.8 21.9 40.9 28.4 33.1 26.0 101.5 26.8 13.5 54.7 22.0 18.3 33.3 21.6 28.5 51.6 31.8 14.2 40.3 31.1 59.8 29.9 32.6 73.0 59.3 19.6 79.7 37.0 73.4 16.6 39.8 23.5 22.2 32.9 58.2 49.2 7.1 6.6 37.5 27.4 35.2 31.7 30.5 22.2 66.8 TRMT10A "MGC27034, RG9MTD2, TRM10" ENSG00000145331 "TRNA methyltransferase 10A" Q8TBZ6 4 99546709-99564039 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Diabetes mellitus, Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 99.5;Spermatogonia: 55.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047601, HPA058241" Uncertain Supported "Nucleoplasm,Nucleoli,Actin filaments,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nucleoli, Actin filaments" Cytosol "HPA047601: AB_2680099, HPA058241: AB_2683651" "unprognostic (5.24e-2)" "unprognostic (1.69e-1)" "unprognostic (1.34e-1)" "unprognostic (1.96e-3)" "unprognostic (2.10e-1)" "unprognostic (5.65e-2)" "unprognostic (1.04e-1)" "unprognostic (1.02e-1)" "unprognostic (1.59e-2)" "unprognostic (3.65e-2)" "unprognostic (1.57e-1)" "unprognostic (3.51e-1)" "unprognostic (7.49e-3)" "unprognostic (3.32e-2)" "unprognostic (2.78e-2)" "prognostic unfavorable (2.14e-4)" "unprognostic (1.68e-2)" 4.3 3.7 2.0 3.1 2.6 2.2 4.4 2.6 2.9 1.9 1.5 3.6 4.3 2.7 3.9 3.6 5.8 3.4 2.3 1.8 2.5 4.9 9.8 2.4 4.4 2.6 2.5 3.3 5.9 3.7 2.3 3.7 2.9 4.1 3.6 2.8 3.9 2.2 3.9 3.7 4.5 2.7 2.7 3.5 4.4 9.9 2.4 4.3 6.1 2.7 4.4 2.9 2.0 4.3 8.2 5.4 10.1 5.7 6.0 8.4 7.8 9.6 3.7 5.8 4.1 4.9 9.4 10.9 3.7 5.6 5.9 4.4 10.9 5.1 8.6 13.7 5.4 8.0 4.4 7.6 5.5 19.6 7.8 5.4 14.4 5.7 14.0 3.0 6.4 10.0 17.5 9.4 4.5 9.4 16.4 3.5 6.5 13.8 5.0 9.5 10.2 7.2 8.5 6.8 6.3 5.8 5.3 28.3 9.9 8.5 9.3 7.8 4.9 6.9 7.2 5.5 11.1 7.0 12.4 10.0 4.9 10.9 4.7 2.7 3.9 2.1 1.8 3.8 1.7 3.5 3.3 3.3 5.2 5.8 3.5 3.2 4.9 3.3 3.4 3.0 3.9 1.9 2.0 2.6 2.6 2.9 1.8 2.5 2.6 2.5 2.9 2.7 2.4 4.3 7.2 3.2 10.3 8.8 8.7 8.2 5.6 8.4 10.2 4.3 12.1 8.6 6.4 11.5 6.6 11.0 4.2 16.8 6.1 10.6 43.0 13.8 46.8 33.5 12.1 7.2 7.2 2.1 5.3 19.3 16.4 6.9 8.6 21.6 8.2 11.0 8.2 32.6 8.5 5.0 4.6 11.1 12.2 8.1 4.1 17.0 6.5 5.0 5.4 1.9 8.4 8.7 5.2 3.5 19.7 14.1 11.0 7.5 10.4 4.8 19.0 31.9 20.6 5.9 13.1 5.7 8.1 99.5 55.0 10.2 9.5 17.5 5.5 8.1 10.6 6.6 WDR93 "C1d-87, CFAP297, FAP297" ENSG00000140527 "WD repeat domain 93" Q6P2C0 15 89690811-89743638 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 8.9;testis: 11.6" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 20.9;Early spermatids: 49.1;Endometrial ciliated cells: 28.1;Late spermatids: 42.4;Respiratory ciliated cells: 47.7;Spermatocytes: 30.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SK-MEL-30: 1.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA046196, HPA048112" Uncertain Uncertain "Actin filaments" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 49: Ciliated cells - Cilium organization" "Actin filaments" "HPA046196: AB_2679582, HPA048112: AB_2680267" "unprognostic (2.56e-3)" "unprognostic (3.21e-3)" "unprognostic (7.31e-2)" "unprognostic (1.54e-2)" "unprognostic (1.90e-2)" "unprognostic (3.01e-1)" "unprognostic (1.15e-2)" "unprognostic (2.08e-2)" "unprognostic (1.22e-2)" "unprognostic (7.40e-2)" "unprognostic (3.03e-1)" "unprognostic (1.66e-1)" "unprognostic (1.07e-1)" "unprognostic (2.40e-2)" "unprognostic (4.73e-2)" "unprognostic (9.84e-2)" "unprognostic (4.44e-2)" 0.4 0.2 0.6 0.0 0.6 0.4 0.7 1.6 0.6 0.6 3.5 0.1 0.0 0.4 4.9 0.0 8.9 0.2 1.2 0.8 1.0 1.0 0.1 1.0 0.2 2.4 2.9 0.4 0.6 0.5 0.8 0.1 1.1 0.6 0.1 2.8 0.3 0.5 0.3 0.2 0.1 0.0 1.6 0.1 0.1 11.6 0.9 0.1 1.8 0.0 0.1 0.0 0.0 1.0 0.3 0.2 0.0 0.1 0.3 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.7 0.0 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.3 0.1 0.1 0.3 0.0 0.3 0.3 0.0 0.4 0.5 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.7 0.0 0.5 0.2 0.7 0.2 1.0 0.1 0.1 0.4 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.6 0.6 1.6 0.6 0.8 1.0 2.4 2.9 1.1 1.6 0.9 1.0 0.1 3.2 0.5 2.9 0.0 0.3 0.7 1.8 0.0 2.7 0.8 0.6 0.5 0.0 4.2 9.2 20.9 0.4 0.1 0.1 3.9 0.8 49.1 28.1 0.6 0.7 0.0 0.0 2.7 0.2 0.3 0.4 0.0 0.8 0.0 0.4 0.4 0.0 0.2 3.3 2.1 0.1 0.0 0.3 0.8 42.4 1.5 0.3 1.8 0.0 0.6 0.6 0.0 0.5 1.0 0.3 1.1 0.7 0.1 0.7 0.0 2.1 47.7 14.8 0.0 0.9 0.6 30.4 5.7 0.0 0.1 0.3 0.6 2.9 0.2 0.4 ZSCAN22 "HKR2, ZNF50" ENSG00000182318 "Zinc finger and SCAN domain containing 22" P10073 19 58326994-58342332 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEK 293: 14.7" "Low region specificity" "Detected in all" HPA006471 Uncertain Uncertain "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 15: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Cytosol" "Actin filaments" "HPA006471: AB_2221026" "unprognostic (5.55e-3)" "unprognostic (2.24e-1)" "unprognostic (6.56e-2)" "unprognostic (1.13e-1)" "unprognostic (1.93e-1)" "unprognostic (3.82e-2)" "unprognostic (2.47e-3)" "unprognostic (1.52e-1)" "unprognostic (2.91e-1)" "unprognostic (1.15e-1)" "unprognostic (2.15e-3)" "unprognostic (5.00e-2)" "unprognostic (7.59e-2)" "unprognostic (2.59e-2)" "unprognostic (1.74e-1)" "unprognostic (5.22e-3)" "unprognostic (1.07e-1)" 1.2 1.5 1.4 1.3 1.7 0.7 1.1 2.9 1.6 1.7 1.0 1.5 1.2 1.5 0.8 1.8 1.3 0.7 1.2 1.3 1.4 1.3 2.4 1.1 1.2 1.4 1.2 1.5 1.4 1.6 2.6 1.2 1.4 1.4 0.9 0.8 1.2 1.0 1.1 2.3 1.3 1.2 0.8 1.4 1.4 1.2 1.2 1.1 1.3 1.0 1.4 1.5 1.5 2.8 2.4 4.2 2.3 3.5 2.6 1.6 2.4 2.0 1.0 1.2 1.1 2.3 1.7 1.9 1.3 1.6 1.5 1.8 3.3 2.2 1.3 3.0 14.7 4.1 4.2 2.1 2.1 3.3 4.2 1.8 2.2 2.6 2.7 2.2 1.8 1.9 4.1 3.6 2.1 1.9 1.6 1.5 2.0 3.0 4.8 2.2 3.6 3.3 1.2 3.1 3.6 2.6 3.0 4.0 2.0 1.8 1.9 2.3 1.8 6.5 1.9 1.6 3.5 3.6 5.3 1.4 2.6 2.2 2.3 0.0 0.8 1.0 2.0 0.7 1.3 0.8 1.1 1.6 1.1 1.0 0.9 1.0 0.2 1.2 0.9 0.5 0.9 1.0 1.4 1.7 2.9 1.6 1.3 1.4 1.4 1.2 1.4 0.8 1.2 2.8 1.1 0.0 4.1 1.6 1.5 1.8 0.6 1.0 0.0 0.7 1.3 0.9 0.6 1.5 1.6 1.8 0.0 0.9 0.8 0.4 1.9 0.9 0.3 1.1 1.2 0.9 0.0 1.7 2.1 0.6 0.9 1.1 1.1 1.6 0.0 1.1 0.0 1.3 0.5 1.7 2.1 0.5 0.0 0.8 0.8 0.0 2.1 2.3 1.8 0.0 1.3 0.5 0.0 1.0 2.2 1.1 1.6 0.4 1.1 0.9 0.8 0.6 1.1 0.7 0.0 1.7 0.8 4.3 1.9 1.1 3.7 0.7 1.2 0.9 1.0 0.4