Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ABCB4 "GBD1, MDR2, MDR3, PFIC-3, PGY3" ENSG00000005471 "ATP binding cassette subfamily B member 4" P21439 7 87401696-87480435 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "liver: 123.2" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 256.1" "Cancer enriched" "Detected in some" 11 "liver cancer: 16.3" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "memory B-cell: 4.4;naive B-cell: 8.1" "Lineage enriched" "Detected in many" 7 "B-cells: 8.1" "Group enriched" "Detected in some" 5 "SH-SY5Y: 12.9;WM-115: 25.7" "Low region specificity" "Detected in many" "HPA049395, HPA053288" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 62: Liver - Hemostasis" "Cluster 17: WM-115 - Nervous system development" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Plasma membrane, Actin filaments" "Focal adhesion sites" "HPA049395: AB_2680745, HPA053288: AB_2682102" "unprognostic (7.92e-2)" "unprognostic (8.87e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-1)" "unprognostic (8.95e-2)" "unprognostic (1.06e-2)" "unprognostic (2.35e-3)" "unprognostic (9.91e-2)" "unprognostic (3.53e-1)" "unprognostic (1.19e-1)" "unprognostic (2.44e-3)" "unprognostic (8.43e-2)" "unprognostic (2.83e-2)" "unprognostic (8.01e-3)" "unprognostic (7.12e-2)" "unprognostic (2.11e-2)" "unprognostic (2.47e-1)" 0.7 7.4 0.8 2.5 0.6 0.9 0.5 0.6 0.9 0.3 0.4 1.1 0.4 0.2 0.6 0.6 0.2 0.8 6.6 0.8 0.6 0.6 123.2 0.2 5.9 0.9 0.6 0.4 0.1 0.0 0.2 0.2 1.0 0.5 1.2 0.4 0.6 0.4 7.5 1.4 2.1 0.3 0.6 5.0 0.6 1.0 0.7 0.7 0.5 4.8 5.2 1.2 0.5 0.7 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.4 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 12.9 0.0 0.6 2.6 0.5 0.2 0.6 0.0 0.2 1.7 0.1 0.0 0.0 0.0 3.2 0.2 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 1.2 8.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.8 0.6 0.6 0.9 0.8 0.6 0.9 0.6 1.0 0.6 0.7 0.7 1.3 0.0 0.5 0.3 22.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 10.2 0.0 0.0 1.8 0.0 1.1 0.1 0.2 0.0 0.1 0.6 0.2 0.2 1.0 0.0 0.4 0.6 0.0 0.3 2.0 0.0 0.2 0.0 0.0 3.3 256.1 0.5 38.7 1.8 0.0 0.0 5.0 1.2 0.4 0.0 1.0 10.6 3.7 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.4 0.3 0.0 0.5 0.7 0.0 0.2 0.0 0.6 1.2 1.2 0.2 0.0 0.4 0.1 0.7 0.0 0.2 0.0 ACACA "ACAC, ACC, ACC1" ENSG00000278540 "Acetyl-CoA carboxylase alpha" Q13085 17 37084992-37406836 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Allosteric enzyme, Ligase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 138.1;Excitatory neurons: 230.7;Inhibitory neurons: 197.8;Oligodendrocyte precursor cells: 181.0;Oligodendrocytes: 186.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013715, HPA036650, HPA063018" Approved Supported "Nucleoli fibrillar center,Actin filaments,Cytosol" NA NA 110000 "Cluster 30: Non-specific - Translation" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "Nucleoli fibrillar center, Actin filaments" "CAB013715: , HPA036650: AB_2675228, HPA063018: AB_2684922" "unprognostic (1.96e-2)" "unprognostic (1.07e-2)" "unprognostic (3.04e-2)" "unprognostic (1.10e-1)" "unprognostic (4.86e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.24e-5)" "unprognostic (8.81e-2)" "unprognostic (6.56e-2)" "unprognostic (2.38e-3)" "unprognostic (3.38e-1)" "unprognostic (2.24e-1)" "unprognostic (6.72e-2)" "unprognostic (1.18e-1)" "unprognostic (4.89e-1)" "unprognostic (4.49e-2)" "unprognostic (2.03e-2)" 16.2 25.4 10.8 3.7 10.8 4.9 22.2 9.0 15.8 11.5 11.3 14.4 5.2 12.1 13.8 25.2 10.8 4.8 7.7 9.5 11.2 13.6 23.3 13.3 2.0 11.1 9.9 11.3 10.5 10.9 19.2 3.8 11.1 26.2 6.4 8.0 14.6 9.6 15.1 15.4 9.6 8.0 8.6 7.3 12.6 16.4 10.3 3.7 8.9 3.6 5.5 19.9 14.6 12.3 34.7 7.0 39.8 42.6 54.7 53.2 13.9 15.2 21.3 15.9 27.5 27.4 5.9 5.0 12.0 24.3 39.4 33.9 7.5 51.1 23.7 13.6 23.2 27.3 15.5 28.0 9.2 14.8 5.3 43.4 29.0 40.2 30.0 18.8 27.5 25.1 66.5 3.2 2.1 27.3 16.3 22.8 30.4 21.5 22.1 24.1 25.3 6.4 36.1 38.5 45.0 17.0 27.8 12.3 12.7 34.8 24.9 16.8 23.8 12.7 20.6 17.3 3.9 8.7 11.5 42.0 11.7 12.3 17.2 0.5 0.8 0.1 0.6 1.3 0.6 0.7 0.7 0.7 1.0 1.1 1.1 0.8 0.3 0.6 0.8 0.7 1.0 0.6 10.8 10.8 9.0 15.8 9.5 11.2 11.1 9.9 11.1 8.6 10.3 12.3 6.8 32.1 51.7 138.1 8.0 11.6 20.8 14.8 22.2 17.2 17.3 11.7 8.0 2.8 16.5 11.0 27.1 16.0 7.0 5.3 9.8 6.7 66.3 19.1 15.6 8.3 9.0 10.7 230.7 8.3 7.6 10.4 15.8 15.9 7.0 19.5 6.4 17.3 5.8 23.5 197.8 7.3 14.2 3.8 4.3 51.2 9.9 6.1 10.6 58.1 4.3 18.2 4.1 181.0 186.9 7.2 6.4 15.8 9.3 22.8 4.8 7.0 10.5 11.8 6.6 10.0 7.8 20.8 20.5 27.8 15.9 16.3 6.4 43.2 10.0 22.0 ACTA2 ACTSA ENSG00000107796 "Actin alpha 2, smooth muscle" P62736 10 88935074-88991339 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 6678.8;seminal vesicle: 5920.3;smooth muscle: 8099.9" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 1007.7;Peritubular cells: 5290.7;Sertoli cells: 3030.6;Smooth muscle cells: 2394.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 58.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 390.6;fHDF/TERT166: 641.1;HHSteC: 625.8;HSkMC: 345.1;hTERT-RPE1: 743.4;SuSa: 296.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 101.0" "CAB000002, CAB003761, CAB013531, HPA041264, HPA041271" Enhanced Supported "Actin filaments" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Actin filaments" "CAB000002: AB_2223500, CAB003761: AB_562031, CAB013531: , HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (7.05e-2)" "unprognostic (2.54e-1)" "unprognostic (2.30e-3)" "unprognostic (3.18e-2)" "unprognostic (3.33e-2)" "unprognostic (6.19e-2)" "unprognostic (2.36e-2)" "unprognostic (1.71e-2)" "unprognostic (4.25e-2)" "unprognostic (1.20e-1)" "unprognostic (1.44e-1)" "unprognostic (6.93e-2)" "prognostic unfavorable (1.37e-8)" "unprognostic (1.87e-3)" "unprognostic (2.30e-1)" "unprognostic (7.91e-2)" "unprognostic (2.09e-3)" 1035.2 241.6 54.0 728.1 61.4 3.9 838.4 52.7 121.1 2000.3 61.4 2755.1 248.9 6678.8 1360.1 1509.9 3104.3 906.1 1069.2 53.4 54.6 312.2 161.8 732.8 173.7 59.0 55.9 798.0 91.4 80.6 60.8 771.3 55.3 2642.8 866.4 8.2 414.7 5920.3 202.1 355.7 701.6 8099.9 54.1 452.1 1427.1 263.9 56.1 56.5 312.0 214.0 48.4 3002.5 1367.0 52.9 3.9 19.0 49.3 102.7 198.1 390.6 9.5 109.8 136.8 11.9 45.4 0.0 8.8 7.2 11.5 641.1 8.6 1.4 1.8 25.4 11.3 60.6 11.3 0.4 5.6 119.3 625.8 0.8 3.2 345.1 44.9 73.9 28.5 743.4 11.3 3.0 0.0 7.1 128.8 10.8 1.0 28.3 2.5 0.2 1.2 1.4 0.2 4.6 27.1 5.0 0.7 7.6 10.2 7.9 1.0 296.8 32.4 1.0 27.9 24.0 4.0 30.2 9.3 21.1 1.6 0.6 29.6 10.2 26.1 28.1 12.3 17.5 17.6 8.7 13.8 6.0 14.1 19.8 10.8 1.8 1.5 10.7 11.1 4.0 14.2 0.4 58.7 10.7 54.0 61.4 52.7 121.1 53.4 54.6 59.0 55.9 55.3 54.1 56.1 52.9 65.4 9.6 6.1 5.5 4.4 43.2 23.4 16.5 22.8 1.1 22.7 1007.7 25.1 2.8 5.2 0.0 6.2 16.3 7.3 1.9 1.9 1.8 11.1 11.1 225.4 41.1 0.0 4.0 3.6 0.9 16.8 316.3 10.7 8.2 5.7 448.9 474.0 4.6 37.7 0.0 1.1 2.7 4.1 5.4 67.6 48.8 141.4 12.6 55.2 61.8 4.2 13.4 4.1 1.0 0.3 2.0 3.0 5290.7 3.7 17.5 3.4 9.5 10.9 1.4 3030.6 72.0 2394.6 4.0 13.8 11.1 40.5 23.7 16.5 36.0 5.7 10.4 ACTN1 ENSG00000072110 "Actinin alpha 1" P12814 14 68874128-68979440 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "smooth muscle: 524.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 351.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 364.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004303, HPA006035" Approved Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 210000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Actin filaments, Focal adhesion sites" "CAB004303: AB_626633, HPA006035: AB_1078095" "unprognostic (4.40e-2)" "unprognostic (1.03e-3)" "unprognostic (2.49e-2)" "unprognostic (1.96e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (6.19e-3)" "prognostic unfavorable (7.63e-5)" "unprognostic (3.62e-1)" "unprognostic (3.23e-2)" "unprognostic (3.16e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (9.08e-10)" "unprognostic (2.87e-2)" "unprognostic (2.00e-1)" "unprognostic (6.05e-3)" "prognostic unfavorable (8.00e-4)" 117.4 40.7 27.3 149.5 55.8 149.3 103.5 0.1 32.0 118.4 20.1 449.8 49.8 313.1 60.3 154.4 152.1 143.9 121.4 29.7 14.7 46.7 61.8 100.0 47.5 24.5 11.0 61.8 46.8 9.1 27.3 96.1 7.3 174.3 109.0 28.2 116.4 295.1 21.7 59.3 106.9 524.5 4.2 55.9 171.7 21.2 32.9 32.6 35.0 13.3 50.7 305.9 83.3 28.8 871.9 262.3 158.6 121.4 275.2 180.5 592.4 749.3 712.0 770.0 571.1 211.8 196.6 0.7 256.5 744.7 310.4 370.9 126.8 790.3 965.2 4.6 38.5 118.2 133.5 179.0 494.0 85.4 14.3 231.7 152.1 479.8 540.3 551.6 428.6 48.2 56.9 1.4 612.0 246.9 10.1 181.1 124.7 217.9 198.1 59.3 294.1 32.6 292.0 225.6 57.0 68.7 649.9 96.8 177.1 474.8 146.0 170.9 546.0 1085.2 432.8 126.9 662.5 113.8 47.8 3.9 314.4 115.7 584.4 64.6 67.5 137.1 5.7 28.8 7.1 0.1 22.7 12.4 45.5 0.2 103.9 92.2 364.2 4.5 8.9 2.0 9.6 89.2 27.3 55.8 0.1 32.0 29.7 14.7 24.5 11.0 7.3 4.2 32.9 28.8 44.7 38.5 25.1 19.6 4.0 119.3 154.9 137.4 82.0 74.7 88.6 157.6 60.3 51.5 36.0 42.3 246.0 155.3 3.0 17.2 3.9 186.8 34.0 65.8 112.8 135.5 38.5 21.9 102.7 144.9 351.8 88.9 34.1 90.2 7.6 15.9 129.5 96.6 79.5 18.5 29.7 57.3 59.0 100.9 82.1 10.7 35.8 96.4 30.2 34.7 105.1 6.0 4.1 9.0 4.3 203.7 28.0 245.6 0.6 132.6 2.4 15.3 47.8 80.8 177.5 30.0 270.6 19.4 18.4 51.8 59.8 66.9 22.7 20.9 47.0 67.1 ACTN2 ENSG00000077522 "Actinin alpha 2" P35609 1 236664141-236764631 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Actin-binding "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 53 "heart muscle: 772.7;skeletal muscle: 2134.7;tongue: 1262.2" "Cell type enriched" "Detected in some" 11 "Cardiomyocytes: 1762.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 10.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+ RasG12V: 2.0;HEK 293: 1.3;HSkMC: 5.9;hTEC/SVTERT24-B: 2.7" "Region enhanced" "Detected in many" "basal ganglia: 66.6" "Region enhanced" "Detected in all" "basal ganglia: 44.5" "HPA006035, HPA008315" Enhanced Uncertain "Actin filaments" NA NA 25000000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Actin filaments" "HPA006035: AB_1078095, HPA008315: AB_1844543" "unprognostic (1.75e-1)" "unprognostic (1.50e-1)" "unprognostic (2.41e-2)" "unprognostic (1.69e-3)" "unprognostic (2.91e-1)" "unprognostic (4.32e-3)" "unprognostic (7.85e-2)" "unprognostic (2.97e-3)" "unprognostic (2.17e-2)" "unprognostic (2.80e-1)" "unprognostic (2.97e-1)" "unprognostic (2.66e-1)" "unprognostic (2.71e-11)" "unprognostic (1.30e-2)" "unprognostic (1.10e-2)" "unprognostic (4.98e-2)" "unprognostic (1.22e-1)" 0.7 0.2 12.0 0.0 26.3 0.1 0.9 8.0 20.1 0.3 11.0 0.4 0.0 0.5 0.0 21.8 0.5 0.7 772.7 13.2 12.1 0.5 0.3 3.9 0.2 9.7 8.1 1.1 1.6 0.1 0.5 0.1 10.7 16.1 0.0 1.3 18.4 0.1 2134.7 1.3 0.5 1.8 8.0 0.2 3.8 4.2 8.7 0.5 0.7 1262.2 0.1 3.5 0.4 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 1.0 2.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.1 1.3 0.0 0.0 0.2 0.0 0.0 0.2 5.9 0.0 2.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 26.3 8.0 20.1 13.2 12.1 9.7 8.1 10.7 8.0 8.7 14.2 0.3 0.0 0.6 18.6 0.0 0.3 0.4 0.0 1.2 2.6 0.4 0.5 1762.9 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 8.6 0.5 1.2 10.4 0.0 0.0 40.9 0.7 0.0 43.7 3.6 1.4 0.0 0.1 1.8 0.2 0.1 0.0 11.3 0.0 0.0 0.0 0.3 24.6 0.6 1.2 0.0 11.2 0.0 0.0 0.0 24.6 156.9 0.2 0.0 0.4 0.0 0.2 0.0 1.4 0.0 1.2 0.0 66.3 12.4 3.1 2.0 1.2 0.1 0.0 0.4 0.4 0.0 0.2 ACTN3 ENSG00000248746 "Actinin alpha 3" Q08043 11 66546395-66563334 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 72 "skeletal muscle: 1670.4" "Group enriched" "Detected in some" 6 "Early spermatids: 6.3;Late spermatids: 16.2;Skeletal myocytes: 15.2" "Cancer enriched" "Detected in single" 5 "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "HDLM-2: 13.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA006035 Uncertain Uncertain "Actin filaments" NA NA 11000000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 37: Myocytes - Muscle contraction" "Actin filaments" "HPA006035: AB_1078095" "unprognostic (2.54e-1)" "unprognostic (1.07e-1)" "unprognostic (6.16e-2)" "unprognostic (1.46e-1)" "unprognostic (1.70e-1)" "unprognostic (3.35e-4)" "unprognostic (1.40e-3)" "unprognostic (5.37e-3)" "unprognostic (5.09e-3)" "unprognostic (1.19e-1)" "unprognostic (1.17e-1)" "unprognostic (1.66e-2)" "unprognostic (6.71e-9)" "unprognostic (2.06e-1)" "unprognostic (6.98e-2)" "unprognostic (5.16e-2)" "unprognostic (2.48e-1)" 0.2 0.0 0.0 0.1 0.1 0.0 0.2 0.9 0.1 0.2 0.0 0.2 0.0 0.1 0.0 1.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.3 0.1 1670.4 0.1 0.1 0.0 0.0 0.1 0.1 4.0 0.0 0.0 0.3 23.3 0.0 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 6.3 0.0 0.0 0.2 1.8 0.0 0.2 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 16.2 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.2 1.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 ACTN4 FSGS1 ENSG00000130402 "Actinin alpha 4" O43707 19 38647649-38731589 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 626.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 947.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001873, HPA006035" Supported Approved "Nuclear bodies,Actin filaments,Cytosol" NA NA 71000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear bodies, Actin filaments" Cytosol "HPA001873: AB_1078096, HPA006035: AB_1078095" "unprognostic (1.03e-1)" "unprognostic (6.34e-2)" "unprognostic (2.97e-2)" "unprognostic (2.52e-2)" "unprognostic (2.37e-1)" "unprognostic (3.34e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (8.82e-4)" "unprognostic (1.70e-1)" "unprognostic (5.85e-3)" "prognostic unfavorable (5.65e-4)" "unprognostic (2.99e-1)" "prognostic favorable (5.25e-5)" "unprognostic (6.59e-2)" "unprognostic (1.91e-1)" "unprognostic (6.75e-3)" "unprognostic (6.52e-2)" 176.5 160.8 22.9 63.9 42.0 74.2 151.4 42.9 42.2 165.2 58.5 168.5 128.7 269.4 11.8 232.8 163.2 46.8 89.0 19.5 27.8 166.7 85.0 174.7 37.5 45.9 42.4 102.5 90.6 42.2 80.0 85.7 44.8 115.6 42.2 26.0 148.1 59.0 52.2 183.4 150.3 73.1 30.2 118.1 120.9 23.6 38.1 18.5 105.4 18.8 24.2 150.2 181.3 63.4 364.6 947.0 92.9 48.6 37.7 50.6 237.2 198.7 162.5 178.8 143.9 335.9 265.1 99.0 409.1 260.6 117.4 185.1 57.4 203.8 38.3 238.3 69.5 139.7 356.1 240.4 103.4 101.7 145.2 95.3 63.4 157.5 79.6 146.9 116.4 26.3 165.0 71.8 127.5 221.2 27.2 44.1 78.4 197.8 177.3 89.5 109.4 43.8 174.6 396.3 83.0 49.8 366.3 210.5 94.7 64.0 94.5 78.8 309.7 249.3 138.7 135.3 476.1 44.1 84.5 67.8 231.7 90.6 476.7 7.6 8.1 17.8 13.2 7.7 9.8 3.2 5.7 13.2 7.0 3.0 0.9 4.4 16.9 24.8 6.7 10.8 9.5 10.6 22.9 42.0 42.9 42.2 19.5 27.8 45.9 42.4 44.8 30.2 38.1 63.4 315.2 179.5 120.0 21.5 45.8 234.8 266.4 155.1 153.7 25.6 134.0 148.1 9.2 143.0 119.4 152.6 14.6 123.7 150.7 626.1 19.6 413.5 2.5 272.0 145.7 206.2 162.0 59.3 46.0 419.3 256.7 77.3 219.7 346.4 73.5 75.9 130.6 108.5 72.6 23.5 22.6 365.5 73.2 65.9 103.7 4.5 41.3 75.4 46.2 48.7 162.2 122.4 120.5 35.2 83.6 532.3 425.2 71.5 91.2 322.1 315.5 104.0 122.1 32.3 190.7 97.2 251.0 36.2 23.7 189.3 202.7 168.0 119.4 115.3 280.6 284.7 AFAP1 "AFAP, AFAP-110" ENSG00000196526 "Actin filament associated protein 1" Q8N556 4 7758714-7939926 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Early spermatids: 170.5;Extravillous trophoblasts: 116.3;Inhibitory neurons: 117.2;Late spermatids: 373.8;Oligodendrocyte precursor cells: 125.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.9" "Group enriched" "Detected in many" 5 "granulocytes: 2.9;T-cells: 1.2" "Cell line enhanced" "Detected in many" "TIME: 126.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015642, CAB024712" Enhanced Supported "Actin filaments,Focal adhesion sites,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Actin filaments, Cytosol" "Focal adhesion sites" "CAB024712: , HPA015642: AB_1844632" "unprognostic (1.12e-1)" "unprognostic (2.78e-2)" "unprognostic (3.97e-1)" "unprognostic (7.29e-2)" "unprognostic (2.02e-1)" "unprognostic (1.93e-1)" "unprognostic (3.30e-1)" "prognostic unfavorable (2.84e-4)" "unprognostic (2.00e-1)" "unprognostic (3.39e-2)" "unprognostic (3.40e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (8.18e-4)" "unprognostic (1.40e-2)" "unprognostic (1.56e-1)" "unprognostic (1.85e-1)" "unprognostic (2.44e-2)" 12.6 3.1 7.0 8.7 5.8 0.7 9.7 4.5 6.9 8.7 2.9 17.6 5.6 15.4 2.0 11.0 8.5 9.4 10.8 5.8 4.5 4.9 1.2 8.5 4.4 3.7 2.7 7.1 3.8 14.7 7.9 12.6 2.8 7.7 9.8 3.4 8.6 10.2 3.5 5.3 7.7 15.4 3.4 4.0 6.7 22.0 3.5 3.1 7.4 2.4 4.8 14.2 8.3 3.5 31.9 23.2 16.2 12.9 15.4 27.8 21.3 46.4 68.1 43.6 40.0 7.4 7.2 0.1 15.2 75.5 72.3 15.1 8.6 18.7 28.6 0.9 5.7 0.0 33.2 4.5 43.0 0.0 0.4 17.2 13.8 54.4 35.5 72.2 53.0 4.8 0.7 6.8 23.0 10.3 0.6 0.0 7.0 13.2 44.3 0.0 12.1 1.5 4.7 4.1 31.8 53.0 15.9 10.9 12.4 21.4 4.1 0.3 126.7 53.0 11.8 69.6 23.0 0.0 0.2 0.0 18.9 0.1 61.9 0.0 0.4 2.9 0.4 0.1 0.5 0.0 0.6 0.6 0.0 0.0 1.2 0.5 1.0 0.0 0.0 0.0 0.5 0.7 7.0 5.8 4.5 6.9 5.8 4.5 3.7 2.7 2.8 3.4 3.5 3.5 22.5 6.4 2.0 4.6 0.2 2.9 9.7 16.2 7.4 1.2 10.2 8.9 5.9 10.0 12.7 11.0 4.2 5.6 2.3 14.8 0.0 19.2 170.5 7.5 17.6 20.1 14.5 0.0 24.7 7.7 116.3 21.1 11.2 8.8 0.0 4.4 14.3 0.0 8.5 0.0 117.2 20.6 0.0 0.3 3.6 373.8 11.1 6.0 1.8 30.9 0.6 10.2 0.0 125.2 5.4 29.9 8.6 12.4 0.6 13.5 6.4 4.2 6.4 0.7 6.6 8.0 13.4 12.5 10.0 6.2 4.3 8.8 7.3 2.6 13.9 9.9 ANG "RAA1, RNASE5" ENSG00000214274 Angiogenin P03950 14 20684177-20698971 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Differentiation, Stress response" "Developmental protein, DNA-binding, Endonuclease, Hydrolase, Nuclease, Protein synthesis inhibitor" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 52 "liver: 3018.1" "Cell type enriched" "Detected in many" 24 "Hepatocytes: 4816.3" "Cancer enriched" "Detected in all" 17 "liver cancer: 279.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.5;myeloid DC: 14.5" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Hep G2: 152.2;OE19: 116.1" "Low region specificity" "Detected in all" HPA055896 Approved "Nucleoli,Nucleoli rim,Mitotic chromosome,Actin filaments" "Secreted to blood" Yes No 308000000 410000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Nucleoli, Nucleoli rim, Mitotic chromosome" "Actin filaments" "HPA055896: " "unprognostic (2.50e-2)" "unprognostic (1.82e-1)" "unprognostic (9.77e-2)" "prognostic favorable (6.85e-4)" "unprognostic (5.71e-3)" "unprognostic (6.99e-2)" "prognostic favorable (7.83e-5)" "unprognostic (1.16e-1)" "unprognostic (3.20e-3)" "unprognostic (9.19e-3)" "unprognostic (1.31e-1)" "unprognostic (3.69e-1)" "unprognostic (6.65e-2)" "unprognostic (1.03e-1)" "unprognostic (3.39e-1)" "unprognostic (2.00e-1)" "unprognostic (3.09e-1)" 37.6 3.0 3.6 6.0 3.5 1.0 37.8 3.5 4.9 38.2 5.6 32.6 23.2 23.4 17.9 9.8 30.5 28.5 16.9 3.6 4.9 18.4 3018.1 18.5 3.5 4.5 4.2 58.1 30.8 5.3 5.0 3.8 4.3 32.7 45.7 2.2 52.6 13.3 6.2 27.4 27.1 10.4 4.5 7.4 58.2 10.2 3.7 1.5 8.8 10.5 4.1 24.8 31.4 4.8 3.7 9.9 2.3 0.0 23.9 27.8 0.3 4.8 8.8 1.1 4.0 5.9 5.1 0.4 1.5 12.0 8.0 3.8 2.8 3.1 1.3 18.4 3.8 0.9 5.1 152.2 5.0 4.0 0.5 22.2 2.5 1.5 5.1 11.8 5.7 4.2 0.2 27.0 3.5 0.7 0.9 1.2 0.7 116.1 10.7 0.7 3.9 11.3 2.3 2.9 0.0 0.4 4.6 1.7 6.5 5.1 4.0 0.7 6.0 1.9 2.8 1.7 0.7 5.9 4.8 0.5 3.2 2.0 5.0 0.0 24.5 0.0 0.6 2.9 0.4 5.8 1.2 1.1 14.5 4.9 0.3 0.2 0.4 0.0 0.1 2.3 0.8 7.1 3.6 3.5 3.5 4.9 3.6 4.9 4.5 4.2 4.3 4.5 3.7 4.8 9.7 28.9 17.7 0.0 9.7 27.1 43.3 39.2 14.2 0.1 33.8 24.8 0.8 194.5 24.6 11.0 0.0 1.6 0.7 32.5 11.7 40.0 1.0 6.2 9.7 11.0 71.0 27.8 0.0 31.6 5.3 48.8 56.1 24.9 0.0 10.7 62.4 4816.3 15.9 0.0 0.0 171.9 12.2 95.9 18.7 2.9 71.1 13.8 23.2 0.0 4.9 10.1 0.0 0.0 0.0 21.6 33.3 24.0 11.7 43.7 91.3 61.2 76.5 0.6 13.1 29.7 17.7 1.0 1.3 9.4 52.4 9.3 5.6 0.5 51.6 39.2 ANKRD23 "DARP, FLJ32449, MARP3" ENSG00000163126 "Ankyrin repeat domain 23" Q86SG2 2 96824526-96857934 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 39 "skeletal muscle: 1438.6;tongue: 448.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 5.0;Respiratory ciliated cells: 7.4;Rod photoreceptor cells: 5.2;Skeletal myocytes: 6.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "Karpas-707: 38.5" "Low region specificity" "Detected in many" HPA036201 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 2: Karpas-707 - Immune response" "Cluster 37: Myocytes - Muscle contraction" "Nucleoplasm, Cytosol" "Actin filaments" "HPA036201: AB_10673347" "unprognostic (2.48e-1)" "unprognostic (7.83e-4)" "unprognostic (4.93e-4)" "unprognostic (1.21e-2)" "unprognostic (4.28e-1)" "unprognostic (3.28e-1)" "unprognostic (3.27e-2)" "unprognostic (6.66e-2)" "unprognostic (2.46e-2)" "unprognostic (3.59e-2)" "unprognostic (1.81e-4)" "unprognostic (1.43e-1)" "unprognostic (2.04e-6)" "unprognostic (2.70e-1)" "unprognostic (1.39e-1)" "unprognostic (1.54e-1)" "unprognostic (2.70e-4)" 0.8 0.9 1.6 0.4 2.1 0.7 1.2 2.2 2.1 1.4 0.6 1.3 0.8 1.8 0.0 6.0 2.5 0.2 24.2 1.5 1.4 0.7 2.2 1.0 0.6 2.5 1.6 1.7 1.6 0.3 10.4 0.2 1.8 5.3 0.1 0.1 18.5 0.3 1438.6 2.5 1.3 0.2 1.5 2.3 0.7 0.7 1.9 0.6 1.1 448.6 0.4 1.2 1.1 2.3 0.5 0.7 0.4 0.8 0.0 0.2 1.1 0.3 0.1 0.2 0.1 0.1 0.2 0.4 0.2 0.1 0.3 0.3 0.3 0.3 0.2 1.1 1.0 0.5 0.8 0.2 0.1 0.8 1.8 0.3 0.3 0.6 0.0 0.2 0.1 1.5 0.9 38.5 0.3 0.9 0.5 0.8 0.4 0.1 0.3 1.4 0.0 5.0 0.2 0.9 1.4 0.2 0.3 0.7 0.0 0.2 1.1 0.0 0.3 0.5 0.6 0.7 0.1 1.7 0.7 0.3 0.4 1.1 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 2.1 2.2 2.1 1.5 1.4 2.5 1.6 1.8 1.5 1.9 2.3 1.1 0.0 1.1 2.0 0.5 0.8 0.5 0.4 0.6 2.6 0.8 2.3 5.0 0.0 1.5 0.0 2.1 0.4 2.1 0.9 0.0 0.3 3.3 1.3 1.9 0.8 0.0 0.4 2.8 1.1 0.2 1.3 0.5 0.7 1.3 1.1 1.4 1.2 0.2 1.7 2.7 1.0 0.0 0.6 0.3 1.8 1.5 0.6 0.0 1.0 0.2 1.1 1.0 0.5 2.9 0.1 0.3 3.0 0.4 0.3 0.6 0.2 7.4 5.2 0.0 6.1 1.6 1.3 0.4 0.4 1.3 0.3 1.1 0.7 0.9 0.2 ANKRD62 DKFZp779B1634 ENSG00000181626 "Ankyrin repeat domain 62" A6NC57 18 12093843-12129764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "brain: 1.1;pancreas: 1.0;testis: 1.6" "Cell type enriched" "Detected in some" 5 "Spermatocytes: 92.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059835 Enhanced Uncertain "Nucleoplasm,Nuclear bodies,Actin filaments" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "Actin filaments" "HPA059835: AB_2684136" "unprognostic (2.45e-2)" "unprognostic (1.18e-1)" "unprognostic (2.37e-3)" "unprognostic (9.46e-2)" "unprognostic (3.01e-1)" "unprognostic (1.98e-1)" "unprognostic (6.61e-2)" "unprognostic (7.95e-2)" "unprognostic (3.27e-1)" "unprognostic (2.55e-4)" "unprognostic (1.13e-1)" "unprognostic (3.28e-2)" "unprognostic (4.52e-3)" "unprognostic (8.70e-2)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.4 0.0 0.6 0.0 0.7 0.0 0.0 0.4 0.1 0.0 1.3 0.3 0.1 0.4 0.3 0.0 0.0 1.7 0.4 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 2.2 0.1 0.2 0.5 0.0 0.0 16.5 1.7 0.6 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.6 0.8 2.6 0.6 0.2 0.0 1.0 0.0 0.1 1.0 1.0 0.2 0.5 1.1 0.4 0.0 0.8 0.2 0.0 0.0 0.9 0.0 1.3 0.3 92.8 15.8 0.5 1.1 0.0 0.2 0.1 0.2 0.5 APBB3 FE65L2 ENSG00000113108 "Amyloid beta precursor protein binding family B member 3" O95704 5 140558268-140564781 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 63.1;Late spermatids: 43.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SCLC-21H: 6.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005571, HPA076196" Approved Approved "Actin filaments,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 43: Testis - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 34: Spermatids - Unknown function" "Actin filaments, Cytosol" "HPA005571: AB_1844912, HPA076196: " "unprognostic (7.63e-2)" "unprognostic (4.58e-2)" "unprognostic (1.13e-2)" "unprognostic (1.36e-2)" "unprognostic (1.29e-1)" "unprognostic (1.40e-3)" "unprognostic (1.44e-1)" "unprognostic (5.06e-2)" "unprognostic (7.22e-2)" "unprognostic (1.98e-1)" "prognostic favorable (6.79e-4)" "unprognostic (9.65e-2)" "prognostic unfavorable (2.06e-6)" "unprognostic (1.06e-1)" "unprognostic (4.59e-1)" "unprognostic (9.38e-2)" "unprognostic (4.67e-2)" 2.2 3.9 7.2 0.0 7.6 0.7 2.3 7.3 10.1 2.0 3.7 2.0 0.2 2.5 1.5 1.5 2.6 0.5 2.3 8.1 9.6 2.5 3.1 1.4 0.5 8.2 6.0 2.5 2.6 1.6 9.9 1.4 8.8 1.9 0.7 6.4 2.5 1.7 2.3 2.0 2.1 0.9 4.9 2.2 2.6 8.5 7.2 0.6 3.1 1.2 0.7 2.2 1.8 5.9 0.4 0.4 0.2 2.0 0.0 0.8 3.3 1.0 1.2 1.3 2.6 1.0 1.1 1.3 2.0 1.7 0.8 0.7 0.0 1.4 0.4 1.6 0.6 0.6 4.0 0.1 2.2 0.7 0.8 5.0 0.6 1.2 1.0 0.3 0.8 3.6 0.1 4.4 1.5 0.9 0.2 1.3 0.8 0.5 2.5 0.3 0.4 1.1 1.2 1.0 6.4 3.0 2.8 0.9 3.7 0.2 2.7 2.8 0.7 0.3 0.6 0.0 0.2 1.7 1.3 0.1 0.8 0.4 0.5 5.6 0.7 0.0 0.7 1.8 0.4 0.2 0.4 0.6 0.6 0.6 0.3 0.6 1.9 0.4 0.3 1.0 0.5 0.6 7.2 7.6 7.3 10.1 8.1 9.6 8.2 6.0 8.8 4.9 7.2 5.9 8.3 3.2 9.3 25.8 6.8 2.8 3.4 5.7 4.0 29.4 9.4 8.3 2.1 14.3 10.1 5.5 0.0 11.7 6.3 5.4 5.9 3.9 63.1 3.9 6.8 6.1 5.4 5.2 13.1 1.5 11.9 7.8 15.3 5.3 10.8 6.2 7.1 17.0 14.5 18.5 13.5 2.8 14.2 18.0 14.2 43.6 5.6 13.8 7.2 8.4 12.6 13.5 5.2 8.5 15.6 2.4 3.7 4.9 3.9 2.3 8.6 3.3 5.6 16.5 0.0 6.4 7.2 19.2 6.9 2.9 2.8 11.8 5.2 4.9 3.6 3.1 APPL1 APPL ENSG00000157500 "Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1" Q9UKG1 3 57227726-57278105 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 28.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011138 Approved Approved "Vesicles,Plasma membrane,Actin filaments,Cytosol" NA No 10000 "Cluster 37: B-cells - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 32: U-937 - Innate immune response" "Cluster 57: B-cells - Immune response" "Vesicles, Plasma membrane" "Actin filaments, Cytosol" "HPA011138: AB_1844959" "unprognostic (1.39e-1)" "unprognostic (3.45e-2)" "unprognostic (1.06e-2)" "unprognostic (2.01e-1)" "unprognostic (3.68e-2)" "unprognostic (2.31e-3)" "unprognostic (1.30e-3)" "unprognostic (1.81e-2)" "unprognostic (1.05e-1)" "unprognostic (8.36e-2)" "unprognostic (9.05e-3)" "unprognostic (5.55e-2)" "prognostic favorable (7.26e-5)" "unprognostic (3.99e-2)" "unprognostic (8.76e-2)" "unprognostic (1.12e-2)" "unprognostic (1.55e-1)" 15.6 11.6 9.5 14.8 9.7 15.1 18.9 12.9 11.3 17.1 6.8 14.2 12.6 17.1 10.6 16.9 11.7 13.0 24.7 9.7 11.3 16.5 12.9 13.6 16.7 9.8 10.1 22.7 29.6 25.1 7.8 14.3 10.1 15.0 14.0 13.5 15.2 14.4 44.2 20.1 14.6 15.3 10.4 15.8 15.2 8.0 10.2 18.9 19.8 26.6 19.6 13.4 11.9 10.7 30.2 12.9 12.2 45.4 21.2 29.7 26.2 15.5 9.5 15.4 17.8 14.9 17.5 47.3 6.2 24.6 24.7 5.9 33.7 27.3 26.6 36.1 15.0 27.6 19.5 16.1 22.7 59.6 19.1 21.8 24.3 19.3 21.3 31.3 25.3 30.2 9.0 30.0 17.8 10.4 48.7 15.4 19.5 21.6 21.7 1.7 49.1 26.1 27.7 16.7 12.5 26.5 21.1 32.3 21.0 16.7 15.7 39.6 23.4 25.1 17.5 37.4 29.9 27.0 41.8 33.2 27.4 29.1 17.1 2.0 5.3 3.8 3.7 4.5 4.9 17.9 3.8 3.3 10.9 28.3 3.3 2.5 1.4 7.4 3.6 18.0 1.9 2.7 9.5 9.7 12.9 11.3 9.7 11.3 9.8 10.1 10.1 10.4 10.2 10.7 82.9 51.3 45.5 19.6 106.6 52.9 47.3 46.9 83.6 40.5 67.2 92.8 100.1 47.1 47.4 42.3 31.3 46.9 70.9 29.0 58.7 58.6 42.5 35.4 92.8 66.2 45.6 20.0 49.7 60.3 44.7 68.6 40.2 59.4 23.4 60.8 40.0 44.1 52.2 52.2 50.4 36.2 42.7 68.6 50.6 22.1 73.0 71.0 19.6 33.7 87.8 56.6 56.7 43.2 62.2 51.7 25.5 76.0 62.8 38.7 41.0 58.8 18.1 55.4 52.6 94.3 61.2 64.9 44.2 105.7 69.6 28.0 45.4 73.7 49.1 25.8 ARAP2 "CENTD1, PARX" ENSG00000047365 "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2" Q8WZ64 4 35948221-36244514 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.9;brain: 92.8" "Cell type enhanced" "Detected in many" "Astrocytes: 285.4;Late spermatids: 167.5;Oligodendrocytes: 781.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 13.7;hTCEpi: 12.7;MOLT-4: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035925 Approved Approved "Actin filaments,Focal adhesion sites" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Focal adhesion sites" "Actin filaments" "HPA035925: AB_10672075" "unprognostic (2.97e-2)" "unprognostic (8.62e-2)" "unprognostic (3.43e-3)" "unprognostic (1.04e-1)" "unprognostic (8.86e-2)" "unprognostic (2.72e-3)" "unprognostic (1.09e-1)" "unprognostic (3.78e-3)" "unprognostic (2.04e-1)" "unprognostic (2.45e-2)" "unprognostic (2.72e-3)" "unprognostic (2.96e-1)" "unprognostic (4.48e-2)" "unprognostic (4.54e-2)" "unprognostic (3.43e-2)" "unprognostic (1.57e-1)" "unprognostic (6.72e-2)" 4.5 2.2 28.9 10.0 70.4 39.9 5.1 19.9 39.5 3.5 0.0 5.3 8.9 3.3 3.8 13.1 3.3 9.3 1.5 24.5 21.5 3.7 9.4 13.4 15.7 34.1 38.8 1.5 7.0 5.4 2.9 3.5 32.6 2.2 5.6 1.4 4.6 2.9 0.7 16.1 8.9 4.3 18.3 11.5 6.1 6.2 32.1 24.6 23.2 0.8 11.0 9.9 6.3 92.8 8.6 0.7 0.8 0.3 0.0 0.0 4.2 0.0 0.0 0.0 0.0 4.2 13.7 4.1 3.2 0.4 0.0 3.2 1.3 6.7 0.0 0.0 7.6 0.1 2.9 0.2 1.6 5.5 0.0 0.4 12.7 0.0 2.7 4.9 0.0 11.1 0.2 0.7 0.0 3.6 12.8 4.5 1.0 6.0 2.6 6.5 0.0 4.7 9.3 8.7 7.3 0.0 0.4 2.1 2.7 0.4 5.6 1.6 0.0 2.3 7.5 0.0 1.1 0.0 0.0 8.0 0.9 6.1 1.9 0.0 0.5 0.0 3.8 1.8 3.5 1.8 2.1 2.7 0.3 0.9 0.7 1.9 0.4 6.7 4.7 1.2 1.1 0.6 28.9 70.4 19.9 39.5 24.5 21.5 34.1 38.8 32.6 18.3 32.1 92.8 18.6 153.8 23.3 285.4 46.1 39.1 32.9 13.5 21.6 0.8 11.2 7.0 2.1 17.2 33.2 7.3 0.0 0.2 100.4 15.5 7.9 7.9 123.6 31.4 3.0 15.8 3.0 8.6 140.8 10.0 0.4 9.4 20.4 50.0 9.5 5.9 3.3 4.2 8.7 0.0 29.9 11.3 6.1 33.2 24.9 167.5 2.8 35.1 5.4 40.3 26.7 5.4 95.8 161.4 781.2 21.5 23.3 0.7 43.0 30.0 17.4 5.8 18.0 1.2 0.0 8.1 3.6 4.2 3.0 37.0 67.5 0.8 90.7 0.1 6.9 44.1 ARHGAP21 "ARHGAP10, KIAA1424" ENSG00000107863 "Rho GTPase activating protein 21" Q5T5U3 10 24583609-24723887 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 111.2" "Cell type enhanced" "Detected in all" "Excitatory neurons: 266.5;Oligodendrocyte precursor cells: 336.7;Oligodendrocytes: 827.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036610, HPA057861" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Cell Junctions, Actin filaments" "Plasma membrane" "HPA036610: AB_10669910, HPA057861: AB_2683546" "unprognostic (7.65e-2)" "unprognostic (1.61e-2)" "unprognostic (1.88e-1)" "unprognostic (5.84e-2)" "unprognostic (2.69e-1)" "unprognostic (3.59e-1)" "unprognostic (1.12e-3)" "unprognostic (5.35e-2)" "unprognostic (9.75e-2)" "unprognostic (3.34e-2)" "unprognostic (2.65e-3)" "unprognostic (3.23e-1)" "unprognostic (3.14e-2)" "unprognostic (1.53e-1)" "unprognostic (3.32e-1)" "unprognostic (1.43e-2)" "unprognostic (2.61e-2)" 28.4 18.0 44.3 10.3 77.7 7.2 16.1 56.7 58.1 19.7 0.0 16.6 12.9 19.9 8.6 10.8 17.5 17.9 21.2 49.1 48.3 11.0 13.1 21.7 5.3 76.3 63.1 31.9 14.9 14.6 12.1 16.6 66.7 10.8 18.5 41.3 24.5 11.5 17.7 6.8 16.3 17.8 48.4 8.9 27.1 14.6 58.0 11.4 12.8 23.0 6.0 13.8 9.0 111.2 59.0 25.1 60.9 52.3 42.2 59.1 21.6 41.6 26.6 24.5 34.0 18.4 36.8 10.9 14.0 64.3 37.7 38.1 31.6 40.4 35.9 38.0 20.5 64.9 54.7 13.8 25.5 0.0 9.9 24.4 45.0 32.1 34.4 36.9 42.3 16.1 27.9 96.3 50.0 11.6 30.2 2.3 9.7 20.8 13.6 7.0 21.4 6.2 17.2 10.2 10.5 10.9 27.9 16.0 32.6 18.1 16.3 9.1 47.8 35.3 22.7 40.0 30.6 11.0 20.3 7.8 36.2 11.4 24.7 0.9 0.2 0.4 0.1 0.4 0.1 0.0 0.2 0.3 0.3 0.0 0.6 0.3 0.0 0.2 0.2 0.4 0.4 0.2 44.3 77.7 56.7 58.1 49.1 48.3 76.3 63.1 66.7 48.4 58.0 111.2 47.9 86.6 33.1 246.8 6.5 29.6 13.2 23.6 14.8 144.0 17.5 26.0 37.4 24.3 45.0 5.5 68.8 23.8 6.9 44.6 1.9 21.4 5.0 36.2 148.7 34.9 16.2 15.2 266.5 27.6 21.0 73.0 82.0 54.2 17.1 135.8 26.0 20.9 14.6 132.9 153.8 28.3 14.2 32.8 31.8 8.3 92.9 38.9 19.6 171.4 11.0 194.0 2.1 336.7 827.4 37.1 34.6 59.5 15.2 27.4 21.9 6.5 30.3 53.5 26.3 60.4 43.2 27.4 35.6 18.1 20.2 12.6 11.8 62.2 29.0 29.5 ARHGAP33 "FLJ39019, SNX26, TCGAP" ENSG00000004777 "Rho GTPase activating protein 33" O14559 19 35774532-35788822 "Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 27.4;Cone photoreceptor cells: 25.0;Horizontal cells: 20.2;Oligodendrocytes: 22.7;Rod photoreceptor cells: 33.7;Spermatocytes: 22.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 58.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030117, HPA030118" Supported Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 43: Testis - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "Actin filaments, Cytosol" "HPA030117: AB_10599306, HPA030118: AB_10601238" "unprognostic (1.44e-3)" "unprognostic (3.40e-2)" "unprognostic (1.07e-1)" "unprognostic (3.33e-2)" "unprognostic (2.66e-1)" "unprognostic (2.82e-3)" "unprognostic (3.61e-3)" "unprognostic (4.80e-2)" "unprognostic (1.45e-1)" "unprognostic (2.99e-2)" "unprognostic (2.97e-3)" "unprognostic (2.40e-2)" "prognostic unfavorable (3.09e-8)" "unprognostic (5.70e-2)" "unprognostic (2.66e-1)" "unprognostic (1.38e-1)" "unprognostic (1.19e-2)" 7.7 8.7 24.3 4.2 28.8 20.5 10.9 14.3 39.1 20.4 8.2 11.2 4.0 13.9 1.3 8.1 17.1 2.8 6.9 30.0 21.0 10.1 5.6 6.8 5.8 19.9 16.5 26.9 11.9 4.2 33.6 1.6 18.0 12.5 1.3 9.9 7.4 3.3 3.4 9.8 9.2 2.0 15.2 11.1 10.4 39.6 19.5 11.7 18.0 1.3 2.2 9.4 13.7 22.1 9.0 5.6 15.5 11.7 0.6 1.5 1.2 7.2 0.9 2.7 1.9 2.3 6.6 5.2 2.6 2.1 2.3 2.4 1.9 2.0 1.0 16.4 3.6 7.6 8.6 2.1 0.7 2.7 58.1 2.2 0.4 2.1 0.8 2.2 1.6 20.4 3.7 22.1 2.4 6.8 18.8 7.4 3.5 3.4 2.5 25.4 2.5 2.5 1.2 1.4 15.4 9.4 3.2 5.7 1.1 1.9 8.3 7.5 3.1 11.0 10.6 5.8 8.5 19.5 4.0 5.2 4.0 8.9 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.3 28.8 14.3 39.1 30.0 21.0 19.9 16.5 18.0 15.2 19.5 22.1 2.7 0.0 1.1 7.8 1.0 1.7 1.0 1.0 4.6 27.4 4.8 4.7 2.3 2.8 2.7 1.8 25.0 0.7 5.1 1.4 0.0 0.4 11.4 6.1 4.8 1.6 3.5 6.5 12.1 0.7 1.0 3.5 3.6 2.5 5.1 7.3 1.1 1.5 1.2 20.2 11.3 2.3 2.0 0.8 1.9 8.9 4.1 0.7 0.0 1.9 0.2 7.3 0.0 19.1 22.7 0.7 0.6 3.0 2.2 0.6 0.3 0.2 4.2 33.7 0.0 4.6 3.1 22.2 6.2 4.2 1.7 0.4 3.6 7.2 2.8 0.6 ARL13A ARL13 ENSG00000174225 "ADP ribosylation factor like GTPase 13A" Q5H913 X 100969708-100990831 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "testis: 5.1" "Group enriched" "Detected in some" 29 "Early spermatids: 69.8;Late spermatids: 55.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "CACO-2: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA037377, HPA037378" Uncertain Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" "Actin filaments, Cytosol" "HPA037377: AB_2675442, HPA037378: AB_10670932" "unprognostic (4.40e-2)" "unprognostic (1.05e-1)" "unprognostic (1.02e-1)" "unprognostic (1.08e-2)" "unprognostic (1.93e-1)" "unprognostic (9.06e-3)" "unprognostic (2.58e-1)" "unprognostic (3.95e-2)" "unprognostic (1.82e-1)" "unprognostic (1.06e-1)" "unprognostic (1.18e-1)" "unprognostic (1.51e-2)" "unprognostic (4.50e-3)" "unprognostic (1.46e-1)" "unprognostic (2.46e-1)" "unprognostic (9.37e-4)" "unprognostic (2.14e-1)" 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.7 0.2 0.0 0.0 0.1 0.1 5.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.4 0.6 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.4 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.6 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 55.5 0.6 0.0 0.0 0.0 0.0 1.6 0.0 0.5 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ARSJ FLJ23548 ENSG00000180801 "Arylsulfatase family member J" Q5FYB0 4 113900284-113979727 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 35.3;Astrocytes: 44.1;Basal prostatic cells: 60.3;Prostatic glandular cells: 49.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 46.4;HUVEC TERT2: 42.2;LHCN-M2: 42.8;TIME: 53.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA036481, HPA036482" Uncertain Enhanced "Actin filaments" "Secreted in other tissues" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Actin filaments" "HPA036481: AB_2675146, HPA036482: AB_10672356" "unprognostic (1.98e-1)" "unprognostic (1.55e-2)" "unprognostic (4.23e-1)" "unprognostic (5.31e-1)" "unprognostic (6.23e-2)" "prognostic unfavorable (6.08e-4)" "unprognostic (2.54e-2)" "unprognostic (2.49e-2)" "unprognostic (1.60e-1)" "unprognostic (1.04e-1)" "unprognostic (5.31e-2)" "unprognostic (2.20e-1)" "prognostic favorable (2.97e-6)" "unprognostic (2.26e-1)" "unprognostic (8.37e-2)" "unprognostic (1.30e-1)" "unprognostic (2.07e-2)" 1.8 1.3 1.5 1.3 1.1 0.0 1.0 5.0 1.4 4.5 0.2 2.4 0.6 2.0 0.9 3.1 2.8 3.6 2.5 1.2 0.9 2.7 1.7 3.3 0.6 0.9 1.1 2.0 1.1 3.0 0.7 4.3 0.7 3.9 3.3 0.6 5.8 2.2 0.2 0.7 0.7 2.2 0.6 0.2 3.5 0.1 1.9 1.5 0.7 0.6 0.3 3.8 2.1 1.1 2.7 5.3 0.6 0.0 10.1 20.5 0.0 46.4 35.5 29.0 11.3 1.3 3.4 0.0 5.7 22.6 10.3 5.0 0.2 11.7 36.2 0.0 2.1 0.0 4.2 0.0 30.6 0.0 0.0 12.7 11.5 19.7 40.0 20.5 42.2 0.0 0.0 0.0 42.8 0.4 0.0 0.0 1.5 0.0 8.4 0.0 5.1 0.0 38.0 0.0 0.0 1.7 3.1 0.5 2.2 7.5 0.2 0.0 53.6 33.3 8.7 5.0 22.3 0.0 0.0 0.0 16.2 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.1 5.0 1.4 1.2 0.9 0.9 1.1 0.7 0.6 1.9 1.1 0.7 35.3 9.8 44.1 0.2 2.9 60.3 23.7 15.9 0.2 4.7 2.9 1.3 11.5 10.8 25.8 0.0 0.3 0.1 7.0 0.0 9.2 0.0 6.2 21.1 4.3 23.4 0.0 27.1 0.9 0.2 13.6 4.6 8.2 0.0 0.0 4.2 1.2 0.5 1.7 1.5 17.3 16.2 0.3 1.6 0.3 2.5 0.3 3.6 7.5 0.0 6.8 1.0 3.0 0.5 5.2 5.0 1.5 0.0 49.6 0.1 4.1 4.6 0.2 0.0 8.6 10.5 0.1 0.3 16.9 1.1 0.4 0.6 3.3 4.1 25.6 ATG4A "APG4A, AUTL2" ENSG00000101844 "Autophagy related 4A cysteine peptidase" Q8WYN0 X 108091668-108154671 "Enzymes, Predicted intracellular proteins" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 84.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036374, HPA064759" Uncertain Approved "Actin filaments,Microtubules" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 6: Erythroid cells - Oxygen transport" Microtubules "Actin filaments" "HPA036374: AB_10672354, HPA064759: AB_2685346" "prognostic unfavorable (1.36e-5)" "unprognostic (1.41e-2)" "unprognostic (3.65e-1)" "unprognostic (2.52e-1)" "unprognostic (1.28e-1)" "unprognostic (1.79e-1)" "unprognostic (1.18e-1)" "unprognostic (2.83e-3)" "unprognostic (2.23e-1)" "unprognostic (3.14e-1)" "unprognostic (2.62e-2)" "unprognostic (4.09e-1)" "unprognostic (1.03e-3)" "unprognostic (7.53e-2)" "unprognostic (2.98e-1)" "unprognostic (5.02e-3)" "unprognostic (1.20e-2)" 8.1 8.5 4.9 7.8 5.2 9.1 7.7 5.2 6.1 7.6 10.4 12.1 12.8 4.7 11.6 8.9 5.6 7.7 11.8 4.7 5.2 14.1 18.1 8.9 8.2 5.3 5.0 2.8 17.2 12.4 6.1 8.0 5.4 5.9 13.1 5.7 13.0 7.1 18.5 5.8 11.4 7.7 5.0 7.7 11.2 2.4 5.7 11.2 11.4 18.6 11.1 8.9 5.1 5.4 13.0 6.5 4.1 7.8 38.2 13.2 5.1 17.5 11.2 9.1 10.6 5.3 6.9 14.0 15.7 14.0 14.5 6.0 11.9 13.0 13.5 24.1 12.9 6.0 10.3 3.7 8.4 13.0 18.8 13.4 13.9 11.1 4.8 8.4 84.9 19.5 18.5 43.5 16.6 12.8 12.1 11.9 7.8 23.6 18.4 8.2 6.9 20.3 13.2 11.3 5.9 4.5 11.2 13.9 7.9 12.4 7.0 11.5 24.0 5.7 2.6 19.1 9.8 20.2 24.0 15.1 11.1 14.6 8.1 28.1 7.8 15.1 11.7 11.3 8.4 9.2 8.9 11.4 10.6 9.9 7.1 12.0 2.4 12.3 7.8 5.4 10.3 8.7 4.9 5.2 5.2 6.1 4.7 5.2 5.3 5.0 5.4 5.0 5.7 5.4 13.6 3.2 10.3 9.1 8.1 5.1 4.9 13.5 2.8 3.2 7.0 4.6 17.4 7.2 12.8 5.5 4.2 6.2 12.4 19.1 27.4 9.6 7.0 10.6 7.4 12.9 6.7 36.7 7.9 17.9 7.5 4.6 8.2 6.0 3.8 3.3 9.7 15.4 9.0 1.7 8.4 9.0 30.5 4.1 3.6 10.0 2.8 7.3 14.2 4.7 6.7 10.3 18.6 7.1 11.6 16.6 8.0 7.5 23.5 5.6 14.7 24.7 17.2 5.0 0.0 4.5 6.9 2.4 3.9 5.9 5.3 10.4 12.0 6.2 5.6 7.3 ATP12A "ATP1AL1, H-K-ATPase, HK" ENSG00000075673 "ATPase H+/K+ transporting non-gastric alpha2 subunit" P54707 13 24680408-24712472 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Potassium transport, Sodium transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 11.2;kidney: 5.4;lymphoid tissue: 14.8;placenta: 5.6;skin 1: 6.2" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 75.6;Club cells: 49.2" "Cancer enhanced" "Detected in many" "testis cancer: 12.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "SuSa: 4.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA039526 Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane, Actin filaments" Cytosol "HPA039526: AB_10673534" "unprognostic (8.33e-3)" "unprognostic (3.58e-2)" "unprognostic (2.93e-1)" "unprognostic (5.21e-3)" "unprognostic (2.58e-1)" "unprognostic (1.21e-2)" "unprognostic (8.03e-3)" "unprognostic (2.64e-1)" "unprognostic (1.50e-1)" "unprognostic (1.18e-1)" "unprognostic (3.39e-1)" "unprognostic (2.24e-1)" "unprognostic (1.78e-1)" "unprognostic (1.67e-1)" "unprognostic (6.80e-2)" "unprognostic (8.22e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.1 0.0 5.4 0.0 0.6 0.0 0.0 0.1 0.0 0.1 0.6 0.0 5.6 0.0 0.2 2.0 0.0 0.1 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 14.8 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.7 1.0 0.0 0.0 0.0 75.6 0.0 0.0 0.2 0.3 0.4 0.0 49.2 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.3 0.5 0.0 0.0 0.0 0.9 0.0 0.0 0.4 0.0 2.2 1.3 0.0 0.0 0.0 0.0 0.0 0.7 0.2 8.2 0.0 0.0 0.1 0.3 0.1 0.0 1.0 0.0 0.0 0.0 1.0 0.6 0.1 1.2 0.0 0.0 0.2 0.0 0.1 13.6 0.0 0.0 0.0 1.8 1.0 1.1 0.0 0.0 0.0 0.1 0.0 0.1 1.3 ATP6V1H "CGI-11, SFD, SFDalpha, SFDbeta, VMA13" ENSG00000047249 "ATPase H+ transporting V1 subunit H" Q9UI12 8 53715543-53843558 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009532, HPA023421" Approved Supported "Plasma membrane,Actin filaments,Cytosol" NA NA 8300 "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Actin filaments, Cytosol" "Plasma membrane" "CAB009532: AB_667834, HPA023421: AB_1845202" "unprognostic (1.67e-3)" "unprognostic (2.53e-2)" "unprognostic (1.41e-2)" "unprognostic (2.16e-2)" "unprognostic (2.38e-1)" "unprognostic (2.25e-2)" "prognostic unfavorable (7.81e-4)" "unprognostic (2.01e-1)" "unprognostic (1.95e-1)" "unprognostic (6.39e-3)" "unprognostic (1.56e-1)" "unprognostic (5.30e-2)" "prognostic favorable (1.46e-7)" "unprognostic (1.06e-1)" "unprognostic (3.37e-2)" "unprognostic (1.38e-2)" "unprognostic (1.64e-1)" 24.1 44.6 42.5 15.9 46.7 25.6 26.0 27.5 58.8 23.9 30.2 31.6 12.9 25.4 32.9 34.1 22.6 20.7 31.2 57.4 38.0 60.5 19.1 24.2 21.4 30.5 30.2 24.1 17.4 47.7 42.4 23.9 32.7 30.2 20.4 37.4 28.7 27.4 37.8 35.2 19.1 24.1 29.4 20.3 31.8 18.5 31.0 26.6 52.4 27.3 22.0 28.5 26.4 37.9 42.8 35.6 29.8 31.8 50.9 32.9 23.4 40.5 44.5 54.8 56.7 33.5 54.1 27.2 38.7 40.9 69.7 67.8 52.6 58.9 56.1 39.9 35.8 28.8 34.3 40.9 69.1 19.6 31.8 46.5 82.3 37.2 66.4 52.5 37.8 28.9 39.4 14.0 81.6 36.0 30.6 32.5 27.4 37.0 17.4 28.2 10.6 18.6 88.4 67.4 23.5 34.9 28.7 54.6 79.5 34.4 64.0 16.3 43.2 24.4 19.7 54.6 25.5 25.9 30.4 32.3 57.8 27.4 27.5 25.7 14.8 36.2 13.2 16.6 14.9 13.6 14.3 15.4 20.2 12.0 14.4 16.0 14.5 22.6 23.4 15.9 20.7 11.8 42.5 46.7 27.5 58.8 57.4 38.0 30.5 30.2 32.7 29.4 31.0 37.9 18.2 38.5 27.4 84.2 39.0 29.6 40.1 55.5 42.1 72.8 27.8 21.0 28.9 38.6 50.3 58.8 112.6 76.0 35.9 39.0 105.7 49.1 8.3 94.1 27.7 25.4 35.3 27.0 154.7 31.1 43.6 23.6 26.0 145.7 15.8 22.0 28.9 21.9 64.7 62.2 105.8 17.4 75.3 43.0 103.6 8.5 43.2 52.9 30.2 42.2 35.1 48.4 37.0 58.3 57.7 44.1 30.1 48.2 20.9 32.5 31.4 64.9 39.6 76.4 19.7 16.8 24.6 28.5 52.9 37.6 31.4 100.0 38.1 36.4 21.8 41.4 AVEN PDCD12 ENSG00000169857 "Apoptosis and caspase activation inhibitor" Q9NQS1 15 33858782-34075155 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 44.0;Oligodendrocytes: 86.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.3" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020863 Approved Approved "Plasma membrane,Actin filaments,Centrosome" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Actin filaments" Centrosome "HPA020863: AB_1845219" "unprognostic (1.54e-3)" "unprognostic (1.99e-1)" "unprognostic (8.93e-2)" "unprognostic (5.77e-2)" "unprognostic (5.57e-2)" "unprognostic (2.05e-1)" "unprognostic (1.18e-1)" "unprognostic (6.32e-3)" "unprognostic (1.70e-1)" "unprognostic (1.40e-1)" "unprognostic (4.14e-3)" "unprognostic (1.79e-1)" "prognostic unfavorable (5.29e-10)" "unprognostic (7.66e-3)" "unprognostic (2.40e-1)" "unprognostic (1.63e-1)" "unprognostic (2.84e-3)" 13.7 11.4 8.5 7.2 8.6 4.4 10.8 8.9 10.1 11.4 10.5 15.2 7.4 12.5 5.2 12.3 11.3 6.4 28.5 8.2 9.2 5.5 16.9 7.2 4.8 9.2 9.0 10.5 20.8 3.0 5.8 12.4 9.4 9.4 9.4 2.5 7.9 9.1 31.1 11.2 7.5 12.5 8.8 6.5 12.3 10.7 9.0 6.9 5.6 13.6 7.9 16.2 10.8 9.1 16.4 26.3 26.0 8.6 21.4 24.1 14.7 41.1 36.2 31.9 19.9 7.2 11.3 15.2 24.8 34.8 24.2 10.4 12.2 26.9 25.7 14.6 7.7 26.1 15.9 20.5 31.5 26.6 18.2 19.8 50.9 18.4 45.8 38.6 35.2 7.6 26.6 21.1 45.6 17.3 10.5 46.1 11.9 22.2 8.5 15.7 14.6 32.2 26.4 21.0 13.4 16.8 22.6 11.6 11.4 10.7 12.6 29.4 24.5 27.7 9.5 12.0 34.6 21.2 17.7 31.1 13.3 31.0 15.2 0.0 0.2 0.0 0.5 0.6 0.6 0.4 0.5 0.2 0.2 0.1 0.2 0.3 0.0 0.5 0.2 2.3 0.9 0.1 8.5 8.6 8.9 10.1 8.2 9.2 9.2 9.0 9.4 8.8 9.0 9.1 9.0 3.2 5.3 16.6 5.6 5.7 8.7 1.8 3.4 5.6 7.5 9.0 32.7 2.8 0.8 0.0 6.2 11.0 10.5 7.4 0.0 2.9 13.8 4.4 14.3 10.2 4.8 9.5 21.8 8.6 44.0 8.5 5.6 5.6 0.0 14.7 8.6 19.1 7.4 8.4 24.1 7.7 0.0 4.1 4.4 6.5 7.5 5.0 3.6 22.5 3.5 10.9 7.2 26.7 86.6 7.0 5.2 10.5 15.6 21.5 9.4 4.6 1.5 5.3 6.6 4.9 9.7 6.2 7.4 12.9 9.7 9.4 6.5 23.1 6.0 14.7 AXL "ARK, JTK11, Tyro7, UFO" ENSG00000167601 "AXL receptor tyrosine kinase" P30530 19 41219223-41261766 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Differentiation, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Oncogene, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 147.2;Kupffer cells: 187.5;Langerhans cells: 185.5;Prostatic glandular cells: 123.4;Sertoli cells: 210.4;Smooth muscle cells: 171.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 11.1;plasmacytoid DC: 25.7" "Group enriched" "Detected in many" 12 "dendritic cells: 25.7;NK-cells: 11.1" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 501.2;U-251 MG: 540.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032501, HPA037422, HPA037423, HPA075217" Uncertain Supported "Vesicles,Plasma membrane,Actin filaments" NA Yes 12100000 72000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "Vesicles, Actin filaments" "CAB032501: AB_2062572, HPA037422: AB_10672347, HPA037423: AB_2675470, HPA075217: " "unprognostic (2.20e-1)" "unprognostic (2.02e-1)" "unprognostic (6.79e-3)" "unprognostic (1.01e-1)" "unprognostic (1.40e-1)" "unprognostic (8.49e-3)" "unprognostic (2.42e-1)" "unprognostic (1.74e-1)" "unprognostic (3.15e-2)" "unprognostic (2.82e-2)" "unprognostic (9.57e-3)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.53e-7)" "unprognostic (1.16e-3)" "unprognostic (1.52e-2)" "unprognostic (5.56e-2)" "unprognostic (4.83e-3)" 43.6 18.8 17.5 15.5 22.6 1.7 26.6 19.7 17.7 36.1 12.4 42.5 11.7 34.4 8.7 17.6 25.4 22.4 26.7 16.6 18.8 9.8 15.0 25.9 6.2 26.8 20.6 24.7 6.3 10.7 7.3 34.2 22.1 19.2 12.6 5.8 10.6 24.6 9.4 20.0 19.0 37.1 20.9 37.7 21.4 18.6 24.0 7.2 16.6 11.3 5.0 32.5 25.2 21.9 408.0 160.0 9.7 1.3 34.6 34.7 0.5 314.5 280.2 450.9 278.2 8.5 185.5 0.2 124.7 501.2 235.3 33.3 0.4 211.8 384.8 0.7 0.3 0.0 100.4 6.3 125.0 0.3 0.3 26.4 3.8 266.7 409.5 254.8 169.8 0.1 15.8 0.5 284.6 0.5 0.2 0.4 4.1 1.0 76.3 0.2 165.3 0.3 202.3 0.2 0.1 0.1 81.5 0.6 1.8 57.4 0.9 7.2 351.8 317.8 214.6 307.7 540.8 0.5 0.9 1.0 211.5 0.5 241.8 1.5 0.3 0.2 0.1 0.4 0.2 0.1 0.3 0.1 6.0 0.1 0.3 0.3 0.3 11.1 0.2 25.7 0.4 0.3 17.5 22.6 19.7 17.7 16.6 18.8 26.8 20.6 22.1 20.9 24.0 21.9 13.5 9.6 3.6 35.9 1.9 41.7 88.3 10.3 3.4 0.5 2.3 14.2 8.6 1.5 4.4 5.5 0.0 4.2 0.8 0.1 0.0 6.9 8.7 6.0 45.8 17.7 0.0 0.0 0.8 0.2 2.1 147.2 1.5 5.4 0.0 17.3 11.0 1.2 28.8 1.7 1.1 0.1 2.0 187.5 185.5 5.5 61.5 61.4 26.6 30.9 3.1 26.8 0.0 11.1 0.5 14.5 0.1 79.7 0.8 123.4 0.3 0.1 2.8 1.2 210.4 38.1 171.1 1.9 2.0 1.2 29.1 11.5 3.6 2.5 0.1 28.0 BBOX1 "BBH, BBOX, G-BBH, gamma-BBH" ENSG00000129151 "Gamma-butyrobetaine hydroxylase 1" O75936 11 27040725-27127809 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carnitine biosynthesis" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 467.9;liver: 131.9" "Cell type enriched" "Detected in many" 7 "Proximal tubular cells: 1623.0" "Group enriched" "Detected in many" 6 "glioma: 23.7;renal cancer: 59.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "hTCEpi: 13.7;RPTEC TERT1: 7.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA007600, HPA027823" Enhanced Approved Uncertain "Vesicles,Actin filaments" NA NA 35000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "Actin filaments" "HPA007600: AB_1845284, HPA027823: AB_10602394" "unprognostic (9.96e-3)" "unprognostic (1.80e-2)" "unprognostic (8.17e-2)" "prognostic unfavorable (6.65e-4)" "unprognostic (7.03e-2)" "unprognostic (6.66e-2)" "unprognostic (7.05e-3)" "unprognostic (1.13e-2)" "unprognostic (3.03e-1)" "unprognostic (6.89e-2)" "unprognostic (2.03e-2)" "unprognostic (1.60e-1)" "prognostic favorable (1.45e-5)" "unprognostic (1.71e-2)" "unprognostic (2.70e-1)" "unprognostic (3.22e-1)" "unprognostic (1.73e-3)" 1.4 0.0 24.3 0.0 23.4 0.0 25.1 28.8 34.0 5.1 17.3 0.2 0.0 0.1 8.1 17.5 9.0 9.6 0.0 22.8 25.6 467.9 131.9 0.3 0.1 27.2 33.1 0.0 0.8 0.0 6.9 0.3 35.0 0.5 0.0 0.4 6.1 4.1 0.9 51.8 0.0 0.0 28.8 0.0 0.2 0.1 25.2 1.1 9.6 0.0 0.6 0.1 11.3 27.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.9 13.7 0.0 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.2 2.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.3 23.4 28.8 34.0 22.8 25.6 27.2 33.1 35.0 28.8 25.2 27.0 0.1 0.0 0.6 66.3 5.3 8.2 9.0 80.9 0.6 0.0 16.3 11.0 0.0 15.7 18.1 46.0 0.0 0.3 0.2 0.0 223.0 0.7 1.1 10.3 0.1 0.3 0.0 0.0 1.1 0.0 0.0 0.4 0.0 0.9 0.0 0.1 0.4 27.9 0.0 0.0 0.8 0.0 12.2 0.6 1.1 1.1 0.0 7.1 1.8 4.7 0.0 13.8 0.0 2.0 0.3 0.1 0.0 0.4 0.0 0.2 0.0 1623.0 9.4 0.4 0.0 0.0 1.4 0.0 0.6 16.9 35.8 0.3 5.0 0.0 0.0 2.6 BCO1 "BCDO, BCDO1, BCMO, BCMO1, FLJ10730" ENSG00000135697 "Beta-carotene oxygenase 1" Q9HAY6 16 81238689-81291142 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 5.0;intestine: 14.6" "Cell type enhanced" "Detected in some" "Astrocytes: 6.2;Distal enterocytes: 4.8;Excitatory neurons: 8.0;Intestinal goblet cells: 5.5;Proximal enterocytes: 13.6;Proximal tubular cells: 8.8" "Cancer enhanced" "Detected in many" "renal cancer: 3.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 11.5;EFO-21: 8.7;HAP1: 3.3;NTERA-2: 4.6;RPTEC TERT1: 8.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA043811 Uncertain "Actin filaments,Centriolar satellite" NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Actin filaments, Centriolar satellite" "HPA043811: AB_10962487" "unprognostic (2.78e-1)" "unprognostic (3.88e-3)" "unprognostic (2.61e-1)" "unprognostic (3.32e-1)" "unprognostic (4.05e-2)" "unprognostic (8.01e-4)" "unprognostic (1.65e-1)" "unprognostic (2.99e-2)" "unprognostic (1.58e-3)" "unprognostic (7.26e-2)" "unprognostic (2.97e-2)" "unprognostic (1.08e-3)" "unprognostic (1.46e-1)" "unprognostic (1.90e-2)" "unprognostic (2.48e-1)" "unprognostic (5.07e-2)" "unprognostic (1.09e-1)" 0.0 0.0 1.8 0.2 1.3 0.0 0.1 0.0 1.2 0.2 5.0 2.6 9.3 0.6 0.2 0.3 0.4 1.2 0.0 2.5 0.2 3.5 0.8 0.2 0.0 0.4 0.4 0.9 0.3 0.0 0.7 0.0 0.1 0.5 3.0 0.2 0.5 1.5 0.1 0.3 14.6 0.3 0.1 0.0 1.9 0.1 0.7 0.2 0.1 0.0 0.0 0.2 0.4 0.6 0.0 11.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.3 2.3 0.0 8.7 0.0 0.3 0.1 3.3 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 4.6 0.8 0.0 0.0 0.0 0.0 8.6 0.3 0.3 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.3 0.0 1.2 2.5 0.2 0.4 0.4 0.1 0.1 0.7 0.6 0.0 0.0 0.0 6.2 0.0 0.0 0.3 0.0 0.6 0.0 0.1 0.0 0.2 0.0 0.0 1.8 0.0 0.5 0.0 4.8 0.0 0.6 0.1 0.9 1.1 0.1 1.2 0.0 8.0 0.0 0.0 0.2 0.0 4.0 0.0 0.1 0.4 0.3 0.1 0.0 3.7 5.5 0.0 0.0 0.0 0.3 1.5 0.1 0.0 1.0 0.0 0.0 0.0 2.5 1.0 0.6 2.1 1.2 0.0 0.1 13.6 8.8 0.0 0.0 0.0 0.1 0.1 0.4 0.2 0.7 0.0 0.3 0.1 0.0 3.0 0.7 BICDL2 CCDC64B ENSG00000162069 "BICD family like cargo adaptor 2" A1A5D9 16 3027682-3036944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 104.8;pancreas: 127.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 52.2;Breast myoepithelial cells: 22.1;Ductal cells: 34.3;Endometrial ciliated cells: 28.9;Exocrine glandular cells: 49.8;Glandular and luminal cells: 28.3;Pancreatic endocrine cells: 35.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 9.0;BEWO: 15.4;CAPAN-2: 14.4;HaCaT: 22.5;MCF7: 22.8;RT4: 10.8;SK-BR-3: 11.0;T-47d: 14.0" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 2.7" HPA043251 Approved Approved "Intermediate filaments,Actin filaments,Cytosol" No NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 30: Mammary glandular cells - Lactation" "Intermediate filaments, Actin filaments, Cytosol" "HPA043251: AB_10794925" "unprognostic (2.00e-1)" "unprognostic (5.37e-2)" "unprognostic (1.71e-1)" "unprognostic (6.06e-3)" "unprognostic (9.65e-5)" "unprognostic (5.79e-3)" "unprognostic (6.47e-2)" "unprognostic (1.75e-2)" "unprognostic (2.45e-1)" "unprognostic (1.66e-2)" "unprognostic (2.05e-2)" "unprognostic (4.71e-2)" "unprognostic (8.56e-2)" "unprognostic (2.55e-2)" "unprognostic (2.38e-1)" "unprognostic (4.32e-2)" "prognostic favorable (9.04e-4)" 0.4 0.0 0.2 1.9 0.2 0.0 8.6 0.4 0.4 20.7 0.1 25.1 10.4 0.7 2.6 104.8 6.0 3.4 0.0 0.2 0.1 5.8 0.9 5.9 0.0 0.6 0.3 0.1 127.2 4.1 1.5 0.3 0.8 16.8 6.4 0.0 44.4 3.2 0.6 43.8 13.5 0.2 0.2 0.2 21.5 0.1 0.3 0.2 6.1 0.0 3.1 11.4 44.3 0.2 9.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 2.6 14.4 0.0 0.0 0.0 0.0 22.5 0.0 0.4 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.1 0.0 6.4 0.0 0.1 0.0 0.2 0.0 10.8 0.2 0.1 0.0 11.0 0.0 0.3 14.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.4 0.4 0.2 0.1 0.6 0.3 0.8 0.2 0.3 0.2 0.3 12.8 18.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 52.2 22.1 0.0 0.0 12.4 16.5 0.0 4.5 1.3 0.0 3.9 34.3 0.0 28.9 2.8 0.5 0.0 0.0 0.0 49.8 6.1 0.6 0.0 28.3 2.5 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 35.8 0.0 0.0 0.1 0.0 0.0 0.2 12.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.5 0.6 0.3 0.0 0.0 BPIFB4 "C20orf186, dJ726C3.5, LPLUNC4" ENSG00000186191 "BPI fold containing family B member 4" P59827 20 33079644-33111751 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "pituitary gland: 8.4" "Cell type enhanced" "Detected in single" "Basal respiratory cells: 2.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HSkMC: 2.3;U-2 OS: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA047388 Approved "Actin filaments,Cytosol" "Secreted - unknown location" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Actin filaments, Cytosol" "HPA047388: " "unprognostic (1.32e-1)" "unprognostic (1.16e-1)" "unprognostic (1.61e-1)" "unprognostic (2.75e-2)" "unprognostic (1.31e-3)" "unprognostic (4.70e-2)" "unprognostic (3.42e-2)" "unprognostic (2.03e-1)" "unprognostic (3.98e-4)" "unprognostic (1.31e-1)" "unprognostic (1.82e-1)" "unprognostic (8.97e-2)" 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 8.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.6 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 BRICD5 "C16orf79, MGC21830" ENSG00000182685 "BRICHOS domain containing 5" Q6PL45 16 2209253-2211950 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 11.8;Cone photoreceptor cells: 25.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 18.4" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "spinal cord: 3.1" HPA063522 Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "Actin filaments" Nucleoplasm "HPA063522: AB_2685029" "prognostic favorable (9.74e-4)" "unprognostic (7.12e-3)" "unprognostic (1.25e-2)" "unprognostic (1.04e-1)" "unprognostic (1.18e-1)" "unprognostic (1.93e-3)" "unprognostic (2.02e-1)" "unprognostic (4.62e-2)" "unprognostic (4.34e-3)" "unprognostic (7.56e-2)" "prognostic favorable (7.01e-4)" "unprognostic (9.84e-3)" "unprognostic (2.65e-2)" "unprognostic (9.79e-2)" "unprognostic (2.88e-1)" "unprognostic (3.57e-1)" "prognostic favorable (8.06e-5)" 5.0 6.6 9.7 3.3 10.4 3.0 5.8 25.5 18.7 9.3 6.1 9.7 4.7 8.2 1.3 4.2 8.6 1.9 15.9 9.3 9.9 19.1 7.9 10.2 4.3 11.4 9.0 7.0 5.5 1.4 14.3 2.6 10.8 11.0 0.6 4.6 5.9 2.5 11.1 4.7 10.4 1.2 6.8 16.7 7.4 17.5 10.1 2.2 23.3 1.6 1.3 8.9 6.0 10.6 3.3 6.3 7.5 4.7 1.2 1.1 15.6 3.1 0.4 1.8 2.6 8.3 8.0 1.6 2.0 0.6 1.9 8.6 1.1 1.1 1.1 6.0 3.4 2.1 18.4 2.0 0.7 0.7 4.7 1.6 2.3 2.5 0.6 2.2 0.9 6.9 2.3 4.3 0.4 8.6 5.1 12.8 8.4 0.7 3.7 16.8 5.6 5.9 2.0 2.5 5.8 5.5 2.9 3.6 3.1 3.0 3.4 4.4 2.3 8.0 6.6 6.7 2.7 13.5 6.6 4.7 1.5 5.0 3.8 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 9.7 10.4 25.5 18.7 9.3 9.9 11.4 9.0 10.8 6.8 10.1 10.6 2.4 3.2 4.4 10.4 1.6 0.4 0.4 1.1 0.0 11.8 1.8 1.5 0.5 0.0 0.7 5.5 25.0 2.0 1.3 2.4 0.0 0.9 2.4 0.9 1.1 2.2 1.2 2.1 5.7 0.6 0.9 1.1 4.1 1.5 4.5 4.8 1.1 1.2 1.2 5.0 5.5 1.0 2.0 1.9 2.0 10.2 1.2 2.8 1.8 2.8 2.5 4.5 4.1 3.5 5.2 1.0 0.8 2.6 1.5 0.9 1.9 0.6 3.4 10.9 0.0 1.2 1.3 4.0 1.9 0.4 1.1 0.8 1.7 1.6 3.1 0.3 BZW2 "HSPC028, MST017, MSTP017" ENSG00000136261 "Basic leucine zipper and W2 domains 2" Q9Y6E2 7 16646131-16706523 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 265.5;skeletal muscle: 367.7;tongue: 258.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 278.2;Extravillous trophoblasts: 875.6;Syncytiotrophoblasts: 762.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022813, HPA026709" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Actin filaments, Cytosol" "HPA022813: AB_1845511, HPA026709: AB_10600752" "unprognostic (2.27e-3)" "unprognostic (1.77e-3)" "unprognostic (5.91e-2)" "unprognostic (4.79e-3)" "unprognostic (2.80e-2)" "unprognostic (7.08e-3)" "prognostic unfavorable (7.86e-8)" "unprognostic (9.13e-3)" "unprognostic (8.49e-3)" "unprognostic (2.81e-2)" "unprognostic (1.83e-3)" "unprognostic (3.37e-2)" "prognostic unfavorable (6.01e-4)" "unprognostic (1.00e-1)" "unprognostic (1.66e-1)" "unprognostic (6.77e-2)" "unprognostic (1.25e-1)" 26.1 18.1 8.5 26.8 10.1 45.7 49.7 6.9 14.3 19.1 9.7 51.2 28.9 18.4 9.9 42.6 20.2 17.2 265.5 10.2 6.3 37.8 18.4 20.0 30.0 5.2 6.3 16.0 30.0 6.7 10.4 80.4 6.5 19.3 56.8 88.0 23.8 34.3 367.7 55.5 30.0 39.0 5.6 16.5 50.2 11.6 6.9 33.0 36.5 258.9 38.4 59.5 26.2 8.8 91.7 81.3 138.2 201.7 67.5 118.3 125.7 126.0 156.3 117.6 124.9 201.8 129.7 208.0 143.7 96.9 87.6 181.6 164.8 141.5 152.0 27.8 99.8 129.6 84.4 117.0 70.5 180.3 79.1 90.6 74.6 104.0 187.7 92.4 171.6 149.7 251.9 43.5 96.9 105.0 90.0 210.4 143.9 259.5 174.1 111.0 91.2 216.6 113.4 152.6 179.9 106.8 50.8 419.9 67.7 156.7 187.8 149.5 97.6 93.1 119.1 141.5 136.3 89.5 92.8 288.1 45.5 220.6 340.3 2.6 46.0 5.0 27.3 55.2 44.6 44.6 39.8 36.9 98.8 42.9 56.8 47.1 2.1 56.8 41.6 38.5 31.8 44.0 8.5 10.1 6.9 14.3 10.2 6.3 5.2 6.3 6.5 5.6 6.9 8.8 32.8 22.4 60.5 3.9 30.0 57.6 69.9 60.5 82.6 55.9 52.3 57.0 278.2 17.2 53.9 47.8 64.6 214.3 26.8 42.4 58.7 47.5 9.8 31.9 43.2 42.9 30.5 63.5 48.6 65.6 875.6 43.5 110.1 40.6 21.0 33.3 8.9 13.7 65.0 6.7 32.0 49.5 61.1 33.4 46.0 6.4 12.2 30.7 24.9 12.2 47.5 19.7 19.6 19.1 17.9 47.0 42.9 9.8 31.9 52.0 19.2 20.8 32.6 106.4 6.6 30.2 54.2 11.3 4.1 99.6 51.6 762.9 29.3 52.6 90.6 79.0 C12orf76 FLJ40142 ENSG00000174456 "Chromosome 12 open reading frame 76" 12 110027028-110073634 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "brain: 77.2;choroid plexus: 44.0" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 174.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 60.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA039713 Uncertain Approved "Plasma membrane,Actin filaments" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 51: Myeloid cells - Hemostasis" "Actin filaments" "Plasma membrane" "HPA039713: AB_2676640" "unprognostic (9.20e-2)" "unprognostic (3.31e-2)" "unprognostic (2.35e-3)" "unprognostic (9.54e-2)" "unprognostic (3.50e-2)" "unprognostic (1.14e-1)" "unprognostic (1.75e-2)" "prognostic favorable (6.44e-5)" "unprognostic (1.39e-1)" "unprognostic (1.47e-1)" "unprognostic (8.86e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (5.74e-5)" "unprognostic (2.09e-1)" "unprognostic (7.85e-2)" "unprognostic (4.12e-2)" "unprognostic (1.26e-1)" 4.0 5.0 58.2 5.4 61.5 2.4 7.4 67.2 76.0 6.8 44.0 6.2 3.5 5.6 9.9 3.9 10.3 3.7 4.0 59.5 61.6 8.4 10.1 8.0 8.5 64.9 63.6 8.4 6.4 3.9 10.2 8.0 67.3 6.7 4.7 16.6 5.0 5.1 6.7 4.6 5.7 3.4 60.0 9.2 4.6 8.3 61.3 7.1 9.6 4.1 6.1 5.5 5.4 77.2 3.8 7.5 10.7 8.8 5.2 12.2 10.9 3.4 3.0 7.3 5.0 4.8 4.3 8.1 4.6 1.8 5.0 8.8 4.2 5.4 5.0 9.8 9.9 8.5 7.2 13.3 7.2 13.6 16.2 13.7 14.9 4.7 11.3 19.7 10.7 13.4 13.0 3.0 5.4 4.1 4.3 25.2 9.4 5.1 6.1 10.5 7.0 12.5 11.2 4.1 26.4 12.5 5.3 2.8 11.1 13.3 8.4 6.2 6.2 3.5 4.9 3.4 1.5 8.4 12.8 4.4 8.2 6.3 3.5 60.0 10.2 11.0 6.4 7.8 9.2 18.6 12.7 7.1 10.9 11.6 17.4 10.2 5.8 18.8 5.2 9.7 12.8 12.0 58.2 61.5 67.2 76.0 59.5 61.6 64.9 63.6 67.3 60.0 61.3 77.2 22.5 32.1 17.0 13.4 15.2 7.9 16.2 18.7 13.6 26.4 24.9 39.8 7.1 18.6 10.5 16.5 2.1 30.2 13.3 6.4 35.2 11.6 31.0 42.3 18.7 18.3 6.1 14.5 32.0 15.1 10.5 17.7 6.6 17.4 5.1 22.8 21.8 22.4 26.4 32.0 28.5 10.7 16.2 24.2 13.1 13.5 26.1 35.9 19.6 15.0 25.3 39.4 24.7 53.3 174.6 11.8 7.5 33.8 10.2 11.7 13.3 38.6 33.9 20.9 6.6 16.4 16.5 25.2 11.3 9.0 8.5 12.0 21.8 15.4 9.5 9.8 CACNA1E "BII, CACH6, CACNL1A6, Cav2.3" ENSG00000198216 "Calcium voltage-gated channel subunit alpha1 E" Q15878 1 181317690-181808084 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "brain: 42.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 188.7;Inhibitory neurons: 116.0;Oligodendrocyte precursor cells: 73.9;Oligodendrocytes: 34.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.6;NB-4: 1.0;NTERA-2: 1.1;U-266/70: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042515, CAB079032" Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Actin filaments, Cytosol" "CAB079032: , HPA042515: " "unprognostic (3.96e-3)" "unprognostic (1.89e-1)" "unprognostic (1.05e-2)" "unprognostic (1.54e-5)" "unprognostic (6.56e-2)" "unprognostic (3.16e-2)" "unprognostic (4.30e-3)" "unprognostic (1.18e-1)" "unprognostic (2.40e-1)" "unprognostic (9.48e-3)" "unprognostic (1.04e-1)" "unprognostic (2.06e-1)" "unprognostic (9.85e-7)" "unprognostic (1.74e-2)" "unprognostic (2.07e-2)" "unprognostic (1.16e-1)" "unprognostic (3.75e-2)" 0.0 1.0 33.5 0.6 30.5 1.2 0.0 0.0 34.6 0.0 0.0 0.1 0.0 0.0 1.5 0.2 0.7 0.0 0.3 42.8 3.4 1.3 0.0 0.1 0.4 4.6 6.2 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.2 0.2 9.7 0.4 0.1 1.0 3.8 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.1 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 33.5 30.5 0.0 34.6 42.8 3.4 4.6 6.2 0.9 9.7 3.8 1.1 0.0 0.0 0.0 3.6 0.0 0.1 0.0 0.0 0.0 4.6 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.4 0.0 0.0 188.7 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 116.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 6.5 0.0 0.2 0.0 73.9 34.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.0 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 CALD1 "CDM, H-CAD, L-CAD" ENSG00000122786 "Caldesmon 1" Q05682 7 134744252-134970729 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 916.1" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1190.3;Leydig cells: 1745.0;Peritubular cells: 2005.6;Sertoli cells: 2294.3;Smooth muscle cells: 2549.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "neutrophil: 1.9" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "BJ hTERT+: 736.3;fHDF/TERT166: 1202.8;U-138 MG: 733.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000006, HPA008066, HPA017330" Enhanced Enhanced "Plasma membrane,Actin filaments" Yes No 39000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Actin filaments" "CAB000006: AB_2065456, HPA008066: AB_1078378, HPA017330: AB_1845917" "unprognostic (2.16e-2)" "unprognostic (1.19e-2)" "unprognostic (2.80e-3)" "unprognostic (3.05e-2)" "unprognostic (4.51e-2)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (1.22e-2)" "prognostic unfavorable (3.73e-4)" "unprognostic (2.07e-1)" "unprognostic (1.27e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.84e-5)" "unprognostic (6.52e-3)" "unprognostic (1.14e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-3)" 225.8 119.2 27.3 164.9 35.0 1.3 161.1 28.1 47.6 241.6 37.2 916.1 80.3 523.3 150.7 275.6 304.4 203.2 115.0 26.9 29.1 134.7 224.4 155.5 75.4 32.3 30.4 326.2 52.5 32.7 53.3 430.0 30.9 348.9 149.8 13.1 70.3 781.7 46.5 76.0 233.1 688.4 27.9 129.2 324.2 52.7 33.4 28.5 114.1 75.2 34.4 505.3 208.0 28.8 115.9 75.3 163.3 146.1 572.7 464.8 161.6 661.6 736.3 227.2 246.6 138.3 3.5 0.7 153.3 1202.8 148.1 26.9 106.0 202.3 308.4 1.5 38.9 4.0 87.8 94.7 375.6 1.5 0.8 360.9 153.6 252.8 147.4 343.6 193.0 0.0 0.6 1.6 338.7 0.3 0.6 3.2 197.7 0.1 25.6 1.4 146.6 2.3 46.9 32.2 29.0 72.1 235.3 31.7 90.0 491.0 7.2 1.4 508.5 733.2 130.0 143.8 230.3 0.9 1.1 1.3 259.0 0.8 573.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.9 0.2 0.0 0.0 0.0 2.9 27.3 35.0 28.1 47.6 26.9 29.1 32.3 30.4 30.9 27.9 33.4 28.8 400.6 22.4 17.6 43.1 7.3 420.4 379.6 218.8 164.4 172.0 115.5 466.1 456.5 228.8 33.5 44.1 6.2 202.7 5.0 0.3 23.5 392.6 61.0 89.4 1190.3 432.9 3.6 16.0 95.4 23.6 903.9 886.9 16.3 206.2 5.1 251.0 422.0 638.4 43.5 92.5 58.3 1.2 28.5 21.0 112.8 83.6 1745.0 38.8 336.2 94.6 8.4 140.6 6.2 98.5 158.8 146.0 0.2 2005.6 4.2 456.9 0.1 332.1 11.3 21.2 2294.3 326.1 2549.3 12.1 12.2 70.1 171.8 276.6 27.5 414.1 0.8 36.7 CAMTA2 KIAA0909 ENSG00000108509 "Calmodulin binding transcription activator 2" O94983 17 4967992-4987675 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Late spermatids: 54.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027835, HPA051147" Supported "Nucleoplasm,Vesicles,Actin filaments,Mitochondria,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Vesicles, Actin filaments, Mitochondria, Cytosol" "HPA027835: , HPA051147: AB_2681362" "unprognostic (2.82e-1)" "unprognostic (3.06e-1)" "unprognostic (1.11e-2)" "unprognostic (1.01e-3)" "unprognostic (1.10e-1)" "unprognostic (3.24e-2)" "unprognostic (2.36e-1)" "unprognostic (4.71e-2)" "unprognostic (2.78e-2)" "unprognostic (7.08e-2)" "prognostic favorable (6.00e-8)" "unprognostic (3.42e-2)" "unprognostic (9.02e-2)" "unprognostic (3.73e-2)" "unprognostic (1.20e-1)" "unprognostic (4.56e-2)" "unprognostic (1.19e-1)" 15.8 15.6 10.7 13.6 15.9 10.3 15.0 5.2 36.7 14.8 0.0 19.6 10.3 17.0 4.4 14.4 14.4 8.7 17.7 24.2 3.4 16.0 12.9 18.4 9.7 10.0 4.4 14.8 17.5 19.2 26.0 7.4 8.5 15.1 10.8 10.7 13.9 11.6 38.0 17.4 19.0 14.2 0.5 21.6 18.6 14.5 7.3 10.4 17.0 27.5 9.5 16.0 13.0 18.4 13.2 23.2 4.2 6.1 27.8 19.0 8.6 12.4 13.8 11.6 10.1 5.9 3.6 15.5 11.9 19.7 9.8 13.1 16.2 19.5 6.6 21.8 20.7 9.8 13.3 6.6 15.9 5.8 40.4 13.4 24.0 10.8 17.1 14.0 19.6 11.8 16.2 13.9 11.0 8.8 10.3 3.7 0.6 15.6 9.5 8.9 4.8 6.1 13.1 13.8 5.8 5.1 7.8 14.1 3.8 7.2 12.6 5.6 25.6 9.1 5.3 9.8 20.6 6.8 8.0 5.6 22.4 11.5 9.2 0.5 1.2 0.9 1.3 1.6 1.0 0.6 0.6 1.2 0.7 0.4 0.8 1.0 3.0 0.6 4.9 1.1 0.5 1.4 10.7 15.9 5.2 36.7 24.2 3.4 10.0 4.4 8.5 0.5 7.3 18.4 15.2 3.2 11.3 11.4 9.2 6.9 3.7 11.6 8.6 14.7 11.9 8.9 8.0 12.8 6.9 11.0 10.4 5.9 9.0 16.1 1.9 7.9 30.1 5.9 12.6 10.0 11.4 7.4 17.9 11.2 9.6 12.3 20.4 11.6 13.3 14.7 16.8 15.3 8.5 35.3 15.7 13.9 20.3 16.7 10.2 54.3 10.2 13.1 3.6 4.7 14.9 6.5 12.3 9.0 9.5 10.6 13.9 9.4 9.0 6.3 20.1 15.4 6.1 11.2 13.1 7.9 14.8 7.2 6.9 8.8 10.4 12.4 11.4 14.4 12.2 4.1 CCDC121 "FLJ13646, FLJ43364" ENSG00000176714 "Coiled-coil domain containing 121" Q6ZUS5 2 27625638-27629012 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 25.3" "Cell type enriched" "Detected in many" 4 "Early spermatids: 186.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 10.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA051791 Uncertain Approved "Actin filaments,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 29: Early spermatids - Spermatogenesis" "Actin filaments, Cytosol" "HPA051791: AB_2681611" "unprognostic (1.52e-1)" "unprognostic (2.05e-2)" "unprognostic (1.52e-1)" "unprognostic (1.90e-1)" "unprognostic (3.93e-1)" "unprognostic (1.28e-1)" "unprognostic (4.71e-3)" "prognostic favorable (4.12e-4)" "unprognostic (4.03e-2)" "unprognostic (1.23e-1)" "unprognostic (5.65e-4)" "unprognostic (7.78e-2)" "prognostic favorable (1.87e-5)" "unprognostic (2.50e-1)" "unprognostic (1.72e-1)" "unprognostic (7.86e-2)" "unprognostic (5.42e-2)" 4.0 3.1 5.1 1.8 5.7 1.3 5.2 6.1 6.3 3.9 5.0 3.0 2.4 4.8 4.4 2.8 7.1 2.6 6.0 4.8 5.6 5.3 2.9 4.0 2.3 8.6 7.2 9.9 2.4 7.7 2.5 3.4 6.0 4.3 3.0 7.2 5.3 5.7 3.6 3.0 2.2 3.4 5.4 4.1 3.4 25.3 8.6 2.4 7.1 5.6 2.2 2.3 1.8 7.8 3.3 3.8 5.1 5.7 9.1 4.0 6.4 1.7 0.8 1.7 0.8 2.9 3.0 1.7 2.6 1.1 4.9 3.1 3.8 1.4 1.8 2.4 4.1 1.0 2.1 3.8 1.7 1.5 2.9 1.3 4.5 0.9 2.4 2.8 3.4 0.8 4.6 2.3 2.4 2.8 1.2 1.6 5.3 4.2 1.9 5.7 12.4 3.0 3.5 2.6 6.6 7.6 1.4 6.3 2.2 4.1 5.2 3.6 1.8 1.5 5.5 1.3 4.7 1.4 1.5 2.5 3.6 2.1 1.8 1.8 1.9 10.8 0.4 2.9 1.3 2.3 1.4 0.5 1.4 1.9 2.3 1.6 4.2 2.3 3.4 0.4 0.3 1.0 5.1 5.7 6.1 6.3 4.8 5.6 8.6 7.2 6.0 5.4 8.6 7.8 7.3 6.4 2.6 1.6 2.9 0.6 1.7 0.8 0.6 5.1 2.4 3.2 3.2 4.3 1.9 0.0 20.9 3.1 1.3 1.9 7.9 3.6 186.5 17.1 5.2 5.8 1.2 1.7 0.7 1.1 2.0 4.2 2.6 7.6 0.0 2.8 5.3 2.0 1.9 3.3 1.1 1.3 2.0 1.6 2.1 44.7 8.7 2.2 1.8 0.0 0.8 12.7 0.0 1.5 2.9 2.0 0.8 6.8 0.3 1.2 1.4 3.9 21.2 12.4 13.1 5.6 3.2 31.0 10.0 1.4 1.1 1.8 1.7 4.9 2.1 0.8 CCDC69 "DKFZP434C171, FLJ13705" ENSG00000198624 "Coiled-coil domain containing 69" A6NI79 5 151181052-151224093 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 351.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 124.5;dendritic cells: 106.9;Granulosa cells: 138.2;NK-cells: 197.8;Plasma cells: 133.6;Theca cells: 132.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 129.2;Daudi: 199.9;U-266/70: 120.5;U-698: 119.1" "Region enhanced" "Detected in some" "cerebellum: 4.8" "Low region specificity" "Detected in all" "HPA043648, HPA052896" Uncertain Approved "Golgi apparatus,Plasma membrane,Actin filaments" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "Golgi apparatus, Actin filaments" "HPA043648: AB_10795877, HPA052896: AB_2681983" "prognostic favorable (3.21e-4)" "unprognostic (2.60e-2)" "unprognostic (1.28e-1)" "unprognostic (2.78e-2)" "unprognostic (5.62e-2)" "unprognostic (8.63e-3)" "unprognostic (3.07e-2)" "unprognostic (6.48e-2)" "unprognostic (2.00e-1)" "unprognostic (9.29e-2)" "unprognostic (3.85e-2)" "unprognostic (1.55e-2)" "unprognostic (3.67e-1)" "unprognostic (4.31e-2)" "unprognostic (3.69e-1)" "unprognostic (2.93e-1)" "unprognostic (2.01e-1)" 108.9 89.6 6.7 45.8 8.4 46.3 60.5 12.2 7.9 15.2 13.4 138.5 19.6 32.9 13.3 54.1 37.1 19.3 96.9 5.9 8.9 10.7 24.0 39.0 70.4 13.3 13.8 27.1 47.5 32.1 8.5 14.8 13.6 23.0 20.5 1.8 14.4 29.4 351.9 13.3 44.7 45.6 11.3 55.4 37.0 13.2 9.2 37.8 11.6 163.8 66.8 87.7 21.9 7.2 8.0 1.6 0.4 6.4 129.2 13.1 4.2 1.5 13.1 2.6 2.4 2.1 1.1 199.9 6.3 0.5 3.3 1.0 3.0 2.8 0.9 0.1 2.7 27.0 0.0 17.5 21.1 9.9 34.4 33.0 0.2 1.0 0.0 2.5 13.1 0.0 23.7 44.0 0.1 0.6 43.8 23.3 7.5 0.1 15.2 36.0 1.0 12.1 0.5 5.9 0.2 0.8 2.4 3.2 1.7 3.2 2.0 24.0 32.0 1.0 6.1 0.6 1.5 120.5 60.1 119.1 1.4 22.2 0.0 30.9 12.4 13.5 11.3 10.9 10.3 5.4 8.8 10.8 10.0 10.4 6.1 6.6 9.6 14.3 10.3 19.3 8.5 11.5 6.7 8.4 12.2 7.9 5.9 8.9 13.3 13.8 13.6 11.3 9.2 7.2 51.0 12.8 78.4 0.7 68.8 2.5 3.0 3.5 1.2 0.4 4.8 2.4 124.5 1.5 13.5 1.8 0.0 7.3 106.9 0.2 0.0 2.9 0.5 26.8 2.7 58.9 1.8 32.2 1.8 20.0 9.6 18.4 7.1 1.3 34.8 138.2 28.2 39.7 7.3 6.7 2.7 0.0 4.1 64.0 12.2 2.4 5.6 46.5 10.6 11.2 73.5 4.9 197.8 1.0 0.6 8.8 0.1 7.9 133.6 3.6 4.5 3.2 51.3 1.4 13.1 4.7 14.8 1.2 1.0 0.7 1.3 35.4 65.7 132.1 0.9 23.5 CCDC71L "C7orf74, FLJ36031" ENSG00000253276 "Coiled-coil domain containing 71 like" Q8N9Z2 7 106654360-106661158 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 78.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067925 Approved Approved "Golgi apparatus,Actin filaments,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Actin filaments" Cytosol "HPA067925: AB_2685925" "unprognostic (1.51e-1)" "prognostic unfavorable (9.08e-4)" "unprognostic (7.26e-2)" "unprognostic (1.10e-2)" "unprognostic (1.78e-2)" "unprognostic (1.95e-3)" "unprognostic (9.94e-2)" "unprognostic (1.74e-1)" "unprognostic (1.60e-1)" "unprognostic (2.38e-3)" "unprognostic (6.03e-2)" "unprognostic (2.83e-1)" "prognostic unfavorable (2.53e-6)" "unprognostic (3.34e-2)" "unprognostic (3.72e-1)" "unprognostic (2.26e-1)" "unprognostic (6.35e-2)" 51.5 9.8 2.7 19.6 2.7 15.8 18.7 2.0 2.9 13.1 3.3 14.6 6.5 16.9 2.8 6.8 36.2 10.8 8.2 2.9 3.2 18.1 46.7 22.1 9.6 8.2 2.8 10.1 9.3 5.2 6.4 3.7 3.7 11.2 5.4 1.0 12.6 6.6 5.3 6.2 15.8 7.2 3.3 18.7 16.3 6.9 4.6 14.5 10.2 2.5 8.0 40.0 9.3 3.6 24.8 5.1 7.4 8.9 16.3 15.4 0.0 37.0 47.5 14.2 15.4 0.7 15.3 16.5 12.6 63.3 27.1 2.8 3.6 10.7 11.7 38.7 8.5 2.1 0.9 0.0 25.5 8.4 19.4 13.2 6.4 6.5 3.7 24.1 50.0 9.2 56.0 39.9 17.1 7.1 11.5 13.3 16.0 2.0 17.0 15.4 2.1 3.3 7.3 1.4 3.2 22.1 23.9 8.6 55.9 15.4 3.9 10.1 22.0 31.4 2.9 3.7 14.6 38.4 3.8 13.5 24.3 10.8 35.3 4.9 0.6 1.8 1.1 0.4 0.8 1.3 0.8 0.8 0.4 0.9 0.4 0.6 4.1 0.6 0.7 1.4 1.7 0.5 2.7 2.7 2.0 2.9 2.9 3.2 8.2 2.8 3.7 3.3 4.6 3.6 44.0 3.2 11.6 1.0 9.4 8.2 50.5 2.1 6.8 4.3 39.9 33.0 6.2 18.6 1.6 5.5 2.1 3.0 26.2 12.9 11.7 7.4 1.2 18.7 78.7 21.4 6.6 11.6 1.8 10.7 7.4 47.8 3.6 20.2 12.0 3.3 45.7 34.4 8.1 6.7 2.8 7.3 4.1 10.0 13.9 2.1 21.8 22.5 12.4 1.9 6.5 5.0 10.3 2.5 1.8 13.9 10.1 17.7 4.3 11.0 10.1 4.7 6.8 4.8 0.0 24.5 30.1 7.1 4.9 4.0 5.1 3.3 13.7 3.4 9.5 18.3 CD274 "B7-H, B7-H1, B7H1, PD-L1, PDCD1LG1, PDL1" ENSG00000120217 "CD274 molecule" Q9NZQ7 9 5450503-5470566 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 16.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 27.7;granulocytes: 28.4;Langerhans cells: 50.9;monocytes: 42.4;Syncytiotrophoblasts: 44.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 6.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.6" "Cell line enhanced" "Detected in many" "HDLM-2: 89.6;HHSteC: 55.5;U-251 MG: 98.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003528, CAB076385" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane, Actin filaments" Nucleoplasm "CAB076385: AB_2687655, HPA003528: " "prognostic favorable (8.89e-4)" "unprognostic (4.54e-2)" "prognostic favorable (1.64e-5)" "unprognostic (1.27e-2)" "unprognostic (2.96e-2)" "unprognostic (1.08e-1)" "unprognostic (4.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.68e-2)" "unprognostic (5.67e-4)" "unprognostic (7.39e-3)" "unprognostic (1.69e-2)" "unprognostic (1.24e-2)" "unprognostic (1.35e-1)" "unprognostic (1.49e-2)" "unprognostic (2.67e-1)" "unprognostic (9.02e-2)" 2.6 2.0 1.0 10.3 0.9 1.9 1.5 0.9 1.2 1.8 0.6 1.4 2.7 1.5 1.8 2.5 1.8 4.0 8.9 0.8 1.9 2.6 3.4 16.8 6.6 1.8 1.6 1.5 1.9 5.0 2.6 6.8 2.0 2.0 2.1 1.2 1.5 1.5 4.5 0.7 1.9 2.2 1.7 10.2 1.9 0.9 1.6 13.0 3.5 4.3 5.3 7.2 1.3 1.1 15.6 0.2 0.0 0.5 0.1 0.1 0.0 30.5 25.7 7.7 10.4 0.0 5.0 0.2 0.6 0.8 3.8 0.6 0.0 13.2 24.6 89.6 0.0 9.0 0.3 0.0 55.5 0.0 0.0 0.5 0.1 15.7 22.9 7.7 15.0 0.9 0.0 2.9 23.4 0.0 0.4 0.1 0.0 0.0 0.3 0.1 4.2 0.8 1.6 0.3 0.0 0.3 0.4 2.4 1.9 2.2 0.1 0.3 28.1 16.1 5.1 0.5 98.1 0.5 0.2 0.3 5.4 0.3 0.2 6.6 0.0 0.2 0.7 0.1 1.2 0.5 1.4 1.1 0.0 0.1 0.7 0.4 3.6 0.3 0.0 0.0 0.7 0.4 1.0 0.9 0.9 1.2 0.8 1.9 1.8 1.6 2.0 1.7 1.6 1.1 3.0 12.8 11.4 0.7 1.9 4.6 1.5 4.4 1.8 1.4 1.4 1.3 7.8 0.0 2.9 0.0 0.0 6.1 2.4 2.6 0.0 5.9 1.0 1.4 0.3 5.5 0.0 3.2 1.9 4.4 27.7 1.9 0.5 0.9 28.4 0.2 7.1 0.8 5.7 0.0 3.3 0.5 4.1 2.9 50.9 0.2 0.3 4.2 3.6 8.4 42.4 0.5 1.0 1.0 0.9 19.0 0.1 0.4 2.2 2.1 1.9 0.4 4.0 0.2 0.0 2.3 0.9 1.0 0.8 1.2 2.6 44.5 3.1 0.1 0.4 2.0 CDC42EP1 "Borg5, CEP1, MSE55" ENSG00000128283 "CDC42 effector protein 1" Q00587 22 37560480-37569405 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 245.6;Exocrine glandular cells: 226.0;Pancreatic endocrine cells: 266.2;Urothelial cells: 161.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 7.3;intermediate monocyte: 1.9;myeloid DC: 2.4" "Group enriched" "Detected in many" 10 "dendritic cells: 2.4;monocytes: 7.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006379, HPA076536" Approved Supported "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" "Nucleoplasm, Actin filaments" "HPA006379: AB_1078486, HPA076536: " "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (2.44e-1)" "unprognostic (3.79e-3)" "unprognostic (5.82e-2)" "unprognostic (4.06e-2)" "unprognostic (4.38e-2)" "unprognostic (5.57e-2)" "unprognostic (9.45e-2)" "unprognostic (1.63e-1)" "unprognostic (2.06e-2)" "unprognostic (1.53e-1)" "unprognostic (1.86e-2)" "unprognostic (2.85e-2)" "unprognostic (3.85e-2)" "unprognostic (3.81e-2)" "unprognostic (1.09e-3)" 76.3 91.2 55.7 16.7 107.5 1.6 58.0 89.9 73.3 68.2 17.6 43.7 31.1 70.7 4.1 93.1 61.0 40.8 53.8 55.9 67.3 50.2 133.1 65.2 11.3 102.8 104.5 60.9 161.6 16.5 18.8 31.8 97.4 41.5 14.4 2.6 102.7 23.9 13.1 71.2 32.7 19.6 70.2 26.2 155.9 23.6 87.5 2.7 33.7 11.1 10.4 38.4 69.6 151.5 125.2 35.4 15.1 67.9 23.7 40.2 73.3 69.9 41.0 78.9 54.3 87.8 15.9 0.2 24.2 81.4 25.4 95.0 17.8 35.1 26.0 15.5 60.7 0.5 33.9 53.6 167.7 0.3 0.6 74.9 52.1 65.0 61.5 63.1 59.2 0.1 78.9 0.7 33.0 42.6 0.3 0.5 13.6 96.5 79.6 0.4 27.5 2.4 27.9 1.9 0.4 2.6 51.2 112.3 112.4 20.6 50.3 11.0 91.6 163.9 98.2 80.0 98.6 0.2 0.8 0.3 65.3 0.7 135.6 0.4 7.3 0.0 0.1 1.9 0.1 0.0 0.1 0.1 2.4 0.3 0.0 0.2 0.2 0.4 0.1 0.3 0.0 3.4 55.7 107.5 89.9 73.3 55.9 67.3 102.8 104.5 97.4 70.2 87.5 151.5 62.4 6.4 19.5 2.3 1.8 46.9 87.2 51.4 21.1 0.1 59.2 31.8 3.5 134.4 41.1 12.9 0.0 98.2 2.0 41.6 1.9 245.6 3.7 4.3 20.0 54.7 11.5 0.0 0.1 226.0 110.3 32.1 133.0 9.0 2.5 1.7 69.7 35.6 13.2 1.7 0.2 66.6 30.5 5.9 29.3 1.7 39.4 5.3 21.4 4.7 8.9 12.8 0.0 2.0 42.7 266.2 45.8 35.3 0.6 122.4 17.5 11.4 14.7 0.3 39.5 22.8 49.5 2.0 0.6 55.9 52.0 112.2 2.2 7.0 61.1 161.3 CDC42EP3 "BORG2, CEP3, UB1" ENSG00000163171 "CDC42 effector protein 3" Q9UKI2 2 37641882-37738468 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 233.5;Langerhans cells: 259.6;Melanocytes: 200.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 24.8" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "LHCN-M2: 607.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034986, HPA061792" Approved Supported "Plasma membrane,Actin filaments" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "HPA034986: AB_10602207, HPA061792: AB_2732670" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (3.92e-2)" "unprognostic (4.11e-3)" "unprognostic (2.38e-2)" "unprognostic (2.72e-3)" "unprognostic (1.41e-1)" "unprognostic (5.76e-2)" "unprognostic (2.68e-1)" "unprognostic (1.72e-1)" "unprognostic (1.84e-1)" "unprognostic (3.81e-1)" "unprognostic (3.14e-3)" "unprognostic (7.30e-3)" "unprognostic (1.97e-1)" "unprognostic (2.97e-1)" "unprognostic (4.53e-2)" 55.2 10.3 4.4 21.9 5.4 86.5 38.8 0.4 24.8 50.5 22.2 42.4 6.1 92.7 10.7 21.1 24.3 21.2 59.6 7.2 6.9 24.4 9.0 29.3 25.5 2.8 3.9 23.8 27.2 8.3 6.8 26.3 5.9 93.4 20.6 15.4 14.6 107.0 57.7 15.1 17.3 96.4 2.2 26.8 14.4 41.9 5.5 36.2 15.9 22.0 23.4 45.4 20.3 3.3 100.2 38.0 21.6 1.2 80.6 42.2 33.8 84.2 221.1 127.5 92.2 69.8 39.3 17.6 66.5 198.9 39.2 47.1 27.1 99.6 129.4 68.2 9.5 31.6 37.5 0.0 156.1 7.1 1.8 129.6 91.7 110.1 243.2 206.6 75.6 7.0 5.0 13.8 607.0 0.8 3.4 59.3 44.1 1.2 23.5 2.8 163.8 9.3 93.1 47.4 23.7 69.9 41.6 29.7 50.2 37.7 9.9 58.8 57.5 152.3 40.0 40.2 86.9 27.0 37.9 5.9 63.1 48.4 215.4 54.6 88.2 6.9 69.4 56.7 74.6 24.9 44.5 60.2 30.9 11.0 14.3 37.3 189.4 38.3 119.5 0.9 35.8 61.5 4.4 5.4 0.4 24.8 7.2 6.9 2.8 3.9 5.9 2.2 5.5 3.3 233.5 6.4 50.4 1.6 50.3 37.1 137.3 81.4 5.7 12.3 31.9 40.1 97.5 12.8 28.9 31.3 35.5 30.8 63.8 7.8 9.8 20.8 51.7 49.6 24.4 113.9 41.2 14.5 15.6 15.9 68.2 29.7 14.3 33.6 129.6 9.2 83.2 1.5 12.2 101.0 34.9 59.6 32.6 44.1 259.6 158.0 15.2 86.0 200.9 9.4 78.6 27.5 106.1 4.0 0.5 24.9 3.0 126.7 43.4 32.7 1.1 5.0 73.3 13.2 0.0 29.2 29.4 67.2 13.6 3.1 13.5 12.0 97.7 1.4 6.0 38.5 CDC42EP4 "BORG4, CEP4, KAIA1777, MGC17125, MGC3740" ENSG00000179604 "CDC42 effector protein 4" Q9H3Q1 17 73283624-73312005 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Horizontal cells: 753.7;Muller glia cells: 570.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 20.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023335, HPA024797" Approved Supported Supported "Plasma membrane,Actin filaments,Microtubules" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "Actin filaments, Microtubules" "Plasma membrane" "HPA023335: AB_10603783, HPA024797: AB_10600696" "unprognostic (8.76e-2)" "unprognostic (4.38e-3)" "unprognostic (1.49e-2)" "unprognostic (5.43e-3)" "unprognostic (6.29e-2)" "unprognostic (9.01e-3)" "unprognostic (2.44e-3)" "unprognostic (1.08e-1)" "unprognostic (8.00e-2)" "unprognostic (2.41e-1)" "unprognostic (4.16e-2)" "unprognostic (6.73e-2)" "unprognostic (3.97e-1)" "unprognostic (1.66e-1)" "unprognostic (1.54e-1)" "unprognostic (1.10e-1)" "unprognostic (1.94e-1)" 94.5 54.9 84.9 15.3 84.7 14.9 74.5 90.6 76.3 47.4 75.0 55.6 35.7 52.7 60.1 33.3 69.4 19.1 50.5 82.2 103.1 28.6 32.2 38.6 16.1 141.9 104.5 70.7 77.5 20.5 45.0 22.9 83.7 38.7 17.4 98.1 41.5 43.1 28.8 40.6 36.0 25.5 103.5 24.1 42.4 20.5 105.9 20.2 45.4 18.8 27.6 33.8 39.5 109.5 30.1 70.1 24.7 20.9 48.8 40.5 65.0 26.2 32.6 24.3 17.9 14.8 42.1 0.1 22.9 31.6 27.6 20.6 17.2 18.0 14.6 1.4 17.0 6.7 35.2 34.7 24.3 1.1 7.3 51.4 14.9 21.2 10.5 19.2 27.9 0.6 18.9 1.4 14.9 23.2 1.2 8.6 13.5 87.8 48.4 0.8 11.0 3.1 28.8 34.3 16.4 24.8 19.7 53.1 18.4 19.0 64.3 9.8 28.7 22.7 47.6 18.1 18.9 1.4 1.2 0.2 37.3 4.7 60.7 3.3 3.2 5.9 0.1 8.5 0.2 0.1 0.0 0.0 4.3 0.0 0.2 0.0 5.4 0.3 20.1 0.1 0.0 2.1 84.9 84.7 90.6 76.3 82.2 103.1 141.9 104.5 83.7 103.5 105.9 109.5 117.1 12.8 15.6 54.9 2.8 48.7 58.5 54.9 97.9 11.5 45.8 37.1 10.8 31.5 29.1 12.9 6.2 32.1 2.5 47.3 11.7 29.4 0.6 29.7 47.6 43.8 31.2 9.1 1.0 43.6 35.0 46.1 31.1 41.2 13.3 19.6 42.8 27.7 6.1 753.7 1.3 41.3 14.2 5.5 30.1 2.7 18.3 9.1 30.2 6.5 11.1 570.4 0.0 2.5 2.5 30.4 33.5 15.4 2.5 42.6 53.1 8.0 18.0 26.2 131.5 98.0 69.9 1.1 2.0 83.2 44.9 84.3 6.0 13.6 30.2 124.1 CDK18 "PCTAIRE3, PCTK3" ENSG00000117266 "Cyclin dependent kinase 18" Q07002 1 205504596-205532793 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 179.6;heart muscle: 116.3" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 462.9" "Cancer enhanced" "Detected in all" "renal cancer: 32.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 38.5;HeLa: 35.3;hTERT-RPE1: 32.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045429 Approved Approved "Actin filaments" No No "Cluster 73: Brain - Neuropeptide signaling" "Cluster 20: HeLa - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Actin filaments" "HPA045429: AB_10961257" "unprognostic (7.95e-2)" "unprognostic (3.42e-1)" "unprognostic (1.51e-1)" "unprognostic (1.33e-1)" "unprognostic (4.38e-2)" "unprognostic (1.30e-1)" "unprognostic (7.06e-3)" "unprognostic (2.93e-1)" "unprognostic (2.95e-1)" "unprognostic (1.13e-1)" "unprognostic (8.89e-2)" "unprognostic (2.81e-1)" "prognostic unfavorable (5.07e-6)" "unprognostic (6.07e-2)" "unprognostic (1.45e-1)" "unprognostic (6.12e-2)" "prognostic favorable (2.81e-5)" 6.1 9.0 68.6 4.1 131.1 1.1 5.1 141.2 82.6 10.9 40.0 13.1 28.8 8.6 3.4 5.7 8.6 10.4 116.3 57.8 90.8 26.5 10.6 11.0 2.8 179.2 148.1 12.6 16.9 7.8 11.5 16.1 147.7 9.2 9.2 13.3 29.2 23.6 6.1 3.3 24.9 7.0 115.2 9.5 35.8 1.6 122.1 3.6 9.5 5.3 3.7 5.7 7.5 179.6 22.2 1.4 0.2 1.3 0.0 0.0 22.6 0.4 4.1 1.0 5.5 9.4 17.8 12.4 3.2 0.2 1.9 21.2 4.9 38.5 0.9 3.4 3.8 3.0 35.3 10.5 4.0 0.1 0.2 2.5 1.9 0.1 0.8 32.2 0.0 18.4 0.1 15.2 0.3 17.7 1.2 0.6 18.4 6.1 0.9 1.6 0.1 16.6 3.6 13.5 7.9 2.8 6.4 3.2 14.2 24.5 15.3 6.2 0.0 0.0 8.1 0.1 0.1 4.1 2.1 2.5 0.2 9.4 3.7 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 68.6 131.1 141.2 82.6 57.8 90.8 179.2 148.1 147.7 115.2 122.1 179.6 4.6 0.0 0.5 12.4 1.0 3.4 6.9 17.4 11.4 7.0 4.6 5.6 29.6 5.7 6.8 73.5 0.0 5.7 0.2 12.1 7.9 18.5 2.4 2.1 0.7 2.9 6.0 1.3 12.0 6.7 2.3 3.8 15.8 4.6 0.0 13.3 2.5 3.7 5.3 0.0 4.5 12.9 2.0 3.8 4.5 4.0 0.9 3.8 3.6 12.2 4.4 28.2 1.0 4.5 462.9 6.5 111.2 1.5 0.9 10.8 35.6 18.7 3.3 1.2 6.6 5.8 12.8 6.6 17.0 5.3 1.3 1.9 1.4 22.7 13.7 9.2 CLK4 ENSG00000113240 "CDC like kinase 4" Q9HAZ1 5 178602664-178630615 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 297.5;Late spermatids: 518.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043746 Approved Approved "Actin filaments" No No "Cluster 5: Granulocytes - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 20: HeLa - Mitochondria" "Cluster 34: Spermatids - Unknown function" "Actin filaments" "HPA043746: AB_2678650" "unprognostic (9.46e-2)" "unprognostic (2.24e-2)" "unprognostic (1.48e-1)" "unprognostic (3.44e-2)" "unprognostic (1.59e-1)" "unprognostic (7.16e-3)" "unprognostic (2.67e-1)" "unprognostic (2.04e-2)" "unprognostic (4.37e-2)" "unprognostic (5.92e-2)" "unprognostic (2.90e-3)" "unprognostic (9.62e-3)" "unprognostic (1.13e-2)" "unprognostic (1.26e-1)" "unprognostic (3.38e-1)" "unprognostic (1.20e-1)" "unprognostic (1.14e-3)" 13.8 11.9 14.0 7.8 14.9 10.4 13.6 22.9 20.1 20.1 14.0 14.4 9.4 12.8 11.9 10.1 13.7 9.8 13.0 14.1 14.5 13.4 13.7 10.8 17.6 15.0 14.0 18.3 17.6 7.9 10.3 10.8 15.2 16.7 6.6 34.4 13.0 8.3 17.8 15.1 12.6 5.5 14.0 18.6 12.5 15.2 14.2 16.6 16.6 21.1 10.0 12.5 21.0 19.3 8.1 7.2 6.8 10.0 19.9 15.9 11.2 7.6 8.8 4.5 8.4 7.7 6.6 4.6 6.0 3.2 5.2 10.4 8.9 6.0 7.5 16.8 6.8 1.8 15.2 8.8 7.4 3.8 5.7 7.2 8.8 7.6 9.6 15.1 3.2 3.1 4.1 13.4 5.5 3.3 5.2 13.8 3.4 5.4 4.5 4.8 6.0 6.7 4.2 2.3 7.4 5.0 8.4 4.7 8.4 3.8 5.1 8.0 6.9 9.5 3.4 4.9 8.4 8.4 3.5 3.5 6.8 9.0 5.0 7.7 5.9 12.7 8.9 4.1 12.6 12.8 9.5 8.4 5.9 10.2 12.2 9.5 16.1 8.4 4.3 7.4 9.6 4.9 14.0 14.9 22.9 20.1 14.1 14.5 15.0 14.0 15.2 14.0 14.2 19.3 31.9 16.0 27.8 45.7 57.8 31.9 44.5 18.4 40.9 70.8 23.5 21.6 22.9 11.5 23.7 14.7 39.6 20.1 52.1 12.2 5.9 9.4 297.5 22.8 30.1 25.4 6.0 38.7 79.6 4.7 18.4 29.2 20.4 19.8 27.9 36.1 18.9 13.0 10.1 28.6 40.5 10.7 14.2 13.9 24.7 518.3 30.7 21.4 16.0 43.1 18.3 29.6 27.8 61.9 60.6 7.2 16.5 29.3 36.5 23.9 25.0 10.1 26.8 81.3 19.7 17.1 30.9 30.3 18.4 19.7 24.6 15.9 42.0 24.1 10.2 26.9 CNN1 "Sm-Calp, SMCC" ENSG00000130176 "Calponin 1" P51911 19 11538767-11550323 "Cancer-related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 1872.4;intestine: 2657.3;smooth muscle: 2207.8" "Group enriched" "Detected in many" 5 "Breast myoepithelial cells: 191.0;Early spermatids: 335.0;Late spermatids: 554.6;Peritubular cells: 221.2;Smooth muscle cells: 180.9" "Cancer enhanced" "Detected in all" "prostate cancer: 142.1;stomach cancer: 103.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 91.5;BJ hTERT+: 34.9;BJ hTERT+ SV40 Large T+: 48.0;BJ hTERT+ SV40 Large T+ RasG12V: 64.6;HBF TERT88: 71.2;K-562: 35.8;SuSa: 72.5;U-2 OS: 34.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000007, HPA014263" Enhanced Approved "Actin filaments" No No "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" "Actin filaments" "CAB000007: AB_2082148, HPA014263: AB_1847039" "unprognostic (4.98e-3)" "unprognostic (1.01e-1)" "unprognostic (3.04e-3)" "unprognostic (1.95e-1)" "unprognostic (2.47e-1)" "unprognostic (4.20e-1)" "unprognostic (5.10e-3)" "unprognostic (1.76e-1)" "unprognostic (1.35e-1)" "unprognostic (7.06e-2)" "unprognostic (2.19e-1)" "unprognostic (2.01e-1)" "prognostic unfavorable (5.43e-6)" "unprognostic (1.70e-2)" "unprognostic (1.07e-1)" "unprognostic (2.78e-3)" "unprognostic (6.11e-3)" 115.6 58.4 6.4 160.6 8.3 0.0 89.7 5.7 14.2 366.9 7.5 2657.3 136.3 1872.4 177.0 677.5 655.6 234.3 274.1 6.8 8.5 42.9 10.6 98.7 7.3 6.1 6.8 114.1 24.2 3.0 9.0 28.4 6.3 676.0 326.4 0.7 61.6 1585.7 21.8 57.8 431.3 2207.8 6.1 22.1 673.7 91.4 7.5 2.6 38.5 11.7 0.9 1386.6 305.7 6.3 0.1 1.3 5.9 1.0 0.6 0.2 3.2 91.5 34.9 48.0 64.6 27.9 0.0 0.4 2.7 26.1 4.4 0.3 0.0 0.0 71.2 0.0 0.2 0.1 0.1 2.3 2.5 0.0 0.4 3.0 0.1 28.7 0.1 1.6 0.0 0.0 35.8 0.0 0.0 0.0 0.3 3.8 2.9 0.0 0.7 0.2 0.6 3.8 0.0 0.0 0.1 1.3 0.1 0.2 0.2 72.5 0.1 0.1 0.4 0.4 34.6 1.2 1.2 0.1 0.4 0.1 3.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 6.4 8.3 5.7 14.2 6.8 8.5 6.1 6.8 6.3 6.1 7.5 6.3 2.4 0.0 0.0 0.0 0.2 4.8 4.1 1.6 0.6 0.0 4.2 191.0 51.4 0.0 0.3 1.8 0.0 0.8 0.7 0.0 0.0 14.5 335.0 3.1 20.7 2.4 0.0 0.0 0.5 0.4 1.0 21.5 0.5 0.7 0.0 0.5 6.8 0.0 2.3 0.0 0.3 0.0 0.0 0.0 9.4 554.6 8.4 0.9 3.6 2.8 0.6 0.5 0.0 0.0 0.1 0.9 0.0 221.2 0.0 4.0 0.0 0.4 0.4 0.0 39.5 1.1 180.9 8.3 19.5 0.4 7.1 0.7 1.1 0.7 0.0 1.1 CNN2 ENSG00000064666 "Calponin 2" Q99439 19 1026586-1039068 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 274.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049095 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA 8400000 "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 58: T-cells - T-cell receptor" Cytosol "Nucleoplasm, Actin filaments" "HPA049095: AB_2680627" "unprognostic (2.52e-2)" "unprognostic (2.69e-1)" "unprognostic (1.74e-1)" "unprognostic (4.49e-2)" "unprognostic (3.89e-1)" "unprognostic (5.31e-2)" "unprognostic (1.33e-1)" "unprognostic (2.56e-1)" "unprognostic (4.58e-2)" "unprognostic (6.56e-2)" "unprognostic (3.60e-2)" "unprognostic (3.33e-2)" "prognostic unfavorable (4.70e-7)" "unprognostic (1.28e-2)" "unprognostic (1.87e-1)" "unprognostic (2.50e-1)" "unprognostic (1.54e-1)" 76.7 22.1 6.3 149.8 7.9 208.8 82.1 9.0 11.2 88.2 30.3 64.1 25.6 118.0 20.0 131.7 88.7 78.8 60.2 6.1 6.7 65.0 42.9 152.2 184.2 9.5 7.7 164.7 69.2 8.6 22.4 37.8 9.6 84.1 33.6 7.5 89.4 68.4 8.1 76.5 64.8 56.0 7.9 154.0 75.1 12.1 9.0 52.2 79.0 7.7 169.9 86.4 79.7 13.3 230.7 75.6 206.9 257.3 104.5 196.9 162.6 204.3 221.8 249.2 192.5 263.0 191.8 151.2 203.9 367.9 58.9 221.3 123.9 324.1 164.7 104.7 10.6 109.6 122.0 205.9 415.0 97.4 230.1 337.2 150.9 158.1 118.5 405.6 142.9 110.1 64.0 225.2 206.0 44.0 8.9 91.5 256.2 184.0 35.0 52.8 72.5 170.9 247.5 265.9 0.5 14.8 252.6 34.3 27.5 149.6 247.6 163.6 349.4 134.8 140.0 210.0 208.9 105.2 86.8 297.8 79.6 117.7 220.9 560.2 142.2 631.5 243.1 180.6 393.5 231.0 301.6 324.2 217.5 201.9 250.1 252.0 845.4 213.8 209.4 96.7 347.3 393.3 6.3 7.9 9.0 11.2 6.1 6.7 9.5 7.7 9.6 7.9 9.0 13.3 10.3 60.9 60.6 0.0 140.4 97.6 274.2 142.9 178.2 1.2 36.5 66.4 6.1 15.7 78.4 36.8 10.4 12.0 66.4 47.0 62.6 63.6 0.5 29.1 52.9 26.3 15.4 44.1 0.1 138.6 99.8 50.4 49.5 40.0 59.5 44.3 37.9 29.8 54.9 0.0 0.1 51.2 42.7 87.9 103.1 1.8 8.1 90.7 14.2 2.8 129.9 0.9 91.6 0.0 0.6 186.9 27.1 76.8 85.8 60.9 3.3 5.9 37.8 7.5 32.9 10.4 70.6 1.7 3.8 135.0 87.8 11.4 160.8 1.7 32.1 170.9 CNN3 ENSG00000117519 "Calponin 3" Q15417 1 94896949-94927223 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "glioma: 315.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 10.5;naive CD4 T-cell: 11.6" "Group enriched" "Detected in many" 12 "B-cells: 10.5;T-cells: 11.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009849, HPA051237" Enhanced Enhanced "Actin filaments,Cytosol" NA NA 660000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments" Cytosol "CAB009849: AB_2276410, HPA051237: AB_2681399" "unprognostic (8.47e-2)" "unprognostic (5.19e-2)" "unprognostic (5.22e-2)" "unprognostic (3.91e-1)" "unprognostic (1.47e-1)" "unprognostic (2.85e-2)" "unprognostic (8.87e-2)" "unprognostic (5.20e-2)" "unprognostic (2.32e-1)" "unprognostic (1.34e-1)" "unprognostic (1.52e-1)" "unprognostic (2.37e-1)" "unprognostic (3.77e-3)" "unprognostic (2.33e-2)" "unprognostic (8.71e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (1.99e-4)" 163.9 255.6 152.7 78.9 153.7 2.1 160.0 148.6 186.3 164.8 147.7 142.4 135.9 214.0 71.0 149.7 147.1 152.3 127.6 151.7 189.9 245.1 143.7 209.0 51.4 197.4 170.9 153.1 83.3 53.1 101.7 256.0 173.1 126.2 82.8 125.0 125.5 133.7 26.3 62.5 100.0 196.0 180.8 94.1 111.8 50.2 164.5 55.1 125.0 52.6 44.3 156.5 166.2 174.0 416.6 77.9 429.0 380.1 286.0 264.2 191.7 197.2 381.3 319.4 511.2 348.7 35.6 0.1 436.6 243.4 315.7 116.2 307.2 169.9 428.1 1.6 113.0 18.8 47.5 256.2 545.0 0.2 0.8 246.2 25.5 394.1 89.4 539.6 282.8 26.7 4.1 35.3 798.9 0.2 19.8 0.9 333.6 0.3 43.3 0.6 524.2 1.8 392.9 156.6 26.3 264.2 163.0 65.0 272.8 301.7 124.8 38.5 182.4 212.2 364.9 80.2 647.0 43.9 27.2 1.5 46.0 0.6 327.1 0.2 0.0 0.0 2.2 0.1 3.4 4.6 2.1 1.2 0.1 10.5 11.6 8.3 0.4 0.9 0.1 0.0 0.0 2.6 152.7 153.7 148.6 186.3 151.7 189.9 197.4 170.9 173.1 180.8 164.5 174.0 183.5 150.6 80.7 82.9 18.1 78.3 435.7 232.3 48.9 11.9 122.2 64.1 42.2 88.6 156.2 126.9 20.9 236.1 3.2 36.0 436.3 275.1 156.1 77.4 151.1 278.3 72.4 20.0 12.9 240.7 40.9 287.8 33.1 104.9 14.0 164.4 373.0 152.1 22.6 1.7 16.9 58.7 429.3 20.1 56.3 150.7 274.6 9.3 197.5 29.0 4.7 394.6 0.0 62.4 22.7 130.8 53.2 382.1 2.6 319.1 117.9 518.5 95.1 14.4 263.0 399.8 374.9 10.8 34.7 91.4 77.7 205.8 14.9 214.5 131.0 327.4 CNNM4 "ACDP4, KIAA1592" ENSG00000158158 "Cyclin and CBS domain divalent metal cation transport mediator 4" Q6P4Q7 2 96760902-96811874 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Biomineralization, Ion transport, Sensory transduction, Transport, Vision" "Amelogenesis imperfecta, Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 38.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 112.6;Distal enterocytes: 103.4;Rod photoreceptor cells: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "SK-BR-3: 45.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017732 Enhanced Uncertain "Plasma membrane,Actin filaments" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Actin filaments" "Plasma membrane" "HPA017732: AB_1847395" "unprognostic (1.98e-3)" "unprognostic (8.95e-3)" "unprognostic (1.11e-1)" "prognostic unfavorable (9.14e-4)" "unprognostic (3.42e-2)" "unprognostic (5.28e-2)" "unprognostic (1.54e-3)" "unprognostic (3.36e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.75e-4)" "unprognostic (4.75e-3)" "unprognostic (3.72e-1)" "unprognostic (8.14e-2)" "unprognostic (3.13e-1)" "unprognostic (3.44e-2)" "unprognostic (1.15e-2)" "unprognostic (1.06e-1)" 2.8 3.6 5.0 6.1 6.8 4.9 7.0 11.2 5.4 5.8 2.8 32.4 6.2 4.0 4.7 7.1 10.4 4.4 12.5 4.9 4.4 6.8 4.4 8.0 4.6 4.1 4.5 5.1 7.4 6.3 9.1 5.8 4.2 5.7 34.3 38.8 6.8 5.1 24.8 7.2 11.3 4.7 3.5 5.3 12.8 7.9 4.5 3.5 9.5 13.1 4.9 5.5 6.4 5.7 11.1 7.2 5.7 10.5 5.8 3.9 15.6 4.8 6.8 6.9 9.3 13.2 11.8 8.1 13.5 5.0 9.5 14.1 14.9 8.1 6.3 16.3 11.7 6.4 4.8 7.2 8.1 3.1 6.2 3.8 10.0 11.0 6.6 4.6 3.8 8.0 3.3 22.3 3.6 15.7 6.6 4.5 7.5 20.5 9.8 9.7 2.6 9.3 6.9 8.6 26.7 8.0 9.1 45.7 6.8 15.9 22.3 5.3 3.4 4.0 8.9 8.8 5.4 7.7 6.6 4.0 5.9 6.1 7.2 1.2 0.4 0.1 0.8 0.4 0.2 0.9 0.4 0.4 0.6 0.5 0.2 0.5 0.2 0.2 0.7 0.4 0.2 0.3 5.0 6.8 11.2 5.4 4.9 4.4 4.1 4.5 4.2 3.5 4.5 5.7 4.5 38.5 7.7 12.4 6.4 5.7 4.9 4.0 4.6 43.1 14.7 11.2 14.1 4.3 11.6 7.3 112.6 5.4 6.1 103.4 0.0 3.2 4.9 14.3 4.4 4.0 10.1 0.8 9.8 4.2 1.7 3.2 12.2 16.1 1.3 5.9 2.2 3.3 3.3 33.7 8.3 26.4 6.1 5.4 4.8 1.6 0.9 5.9 0.0 8.4 2.3 8.3 2.1 11.1 14.6 5.2 21.3 1.2 4.5 4.1 22.3 1.2 10.6 51.5 0.0 4.6 4.3 4.6 2.5 7.3 4.1 6.7 5.4 6.7 26.5 6.1 CNR1 "CANN6, CB-R, CB1, CB1A, CB1K5, CNR" ENSG00000118432 "Cannabinoid receptor 1" P21554 6 88139864-88166359 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 23.0;brain: 25.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 44.6;Inhibitory neurons: 200.3;Sertoli cells: 98.6" "Cancer enriched" "Detected in many" 13 "glioma: 12.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC diff: 81.4;HSkMC: 53.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042256, HPA069945" Enhanced Supported Supported "Plasma membrane,Actin filaments" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Actin filaments" "HPA042256: AB_2677917, HPA069945: " "unprognostic (1.28e-1)" "unprognostic (7.04e-2)" "unprognostic (4.61e-2)" "unprognostic (4.08e-3)" "unprognostic (1.21e-1)" "unprognostic (1.07e-3)" "unprognostic (1.37e-1)" "unprognostic (2.07e-2)" "unprognostic (2.49e-1)" "unprognostic (1.16e-2)" "unprognostic (2.74e-2)" "unprognostic (2.68e-1)" "unprognostic (1.70e-1)" "unprognostic (5.59e-3)" "unprognostic (2.68e-3)" "unprognostic (5.88e-2)" "unprognostic (7.00e-2)" 23.0 5.4 10.4 3.5 25.1 0.7 16.9 7.5 22.8 5.7 0.0 12.3 1.1 6.9 2.6 2.4 11.2 2.0 1.0 19.5 11.8 0.9 0.1 4.0 4.4 9.9 1.1 3.8 1.5 0.5 20.7 3.1 0.5 2.9 2.9 1.5 2.6 2.1 2.4 3.8 10.5 3.6 0.0 1.7 4.3 1.2 18.0 1.3 5.1 1.2 6.6 4.1 5.1 3.0 0.0 0.1 3.8 0.0 81.4 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.2 1.9 2.9 0.0 5.3 0.0 0.0 53.8 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.4 0.5 0.0 6.8 0.0 1.7 0.1 0.0 0.0 0.0 0.3 0.0 1.4 4.9 0.0 0.0 0.1 0.0 0.0 1.6 7.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.4 25.1 7.5 22.8 19.5 11.8 9.9 1.1 0.5 0.0 18.0 3.0 3.4 0.0 10.4 3.6 7.1 0.6 0.5 0.0 0.0 1.7 0.1 0.4 0.9 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.2 0.0 0.4 3.8 0.0 0.0 44.6 0.0 0.0 0.9 1.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 200.3 0.0 0.0 0.3 0.8 0.0 1.5 0.2 0.0 5.6 0.0 0.0 0.0 9.0 3.2 0.0 0.1 0.4 4.2 0.0 0.0 0.0 0.0 0.2 98.6 6.4 12.4 0.0 0.5 0.2 0.1 0.1 0.5 0.0 0.0 0.8 CORIN "ATC2, CRN, Lrp4, PRSC, TMPRSS10" ENSG00000145244 "Corin, serine peptidase" Q9Y5Q5 4 47593999-47838106 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "heart muscle: 56.9" "Cell type enriched" "Detected in some" 6 "Cardiomyocytes: 69.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "ASC TERT1: 44.0" "Region enhanced" "Detected in some" "basal ganglia: 2.6" "Low region specificity" "Detected in some" HPA070941 Approved "Nuclear bodies,Plasma membrane,Actin filaments" "Intracellular and membrane" Yes No "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Nuclear bodies, Actin filaments" "HPA070941: AB_2686324" "unprognostic (1.05e-1)" "unprognostic (2.52e-1)" "unprognostic (1.14e-1)" "unprognostic (1.93e-1)" "unprognostic (2.10e-1)" "unprognostic (3.18e-1)" "unprognostic (3.58e-4)" "unprognostic (3.19e-1)" "unprognostic (3.67e-2)" "unprognostic (8.22e-2)" "unprognostic (9.78e-2)" "unprognostic (6.53e-2)" "unprognostic (1.18e-1)" "unprognostic (2.86e-2)" "unprognostic (5.18e-2)" "unprognostic (7.22e-2)" "unprognostic (1.33e-2)" 0.4 0.1 0.1 0.1 0.1 0.0 1.0 0.1 0.2 2.1 0.6 0.3 0.1 4.5 0.6 0.9 1.4 4.5 56.9 0.0 0.3 1.0 0.1 1.9 0.0 0.7 0.6 0.5 0.2 1.1 1.9 0.4 0.1 2.3 0.0 0.3 0.4 6.1 0.1 7.5 0.3 0.7 0.1 1.1 0.5 2.5 0.3 0.1 0.1 0.1 0.1 1.2 3.9 0.1 0.0 0.0 0.1 0.3 10.3 44.0 0.0 2.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 2.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.9 1.4 0.0 0.3 0.2 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.3 0.7 0.6 0.1 0.1 0.3 0.1 0.3 0.0 7.5 1.0 0.0 3.8 0.3 0.0 0.0 1.0 8.3 0.3 69.4 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.1 1.3 1.0 0.0 0.0 6.5 0.0 0.0 9.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 10.8 0.0 0.0 0.6 5.5 2.0 4.7 0.1 5.4 1.0 0.0 0.7 0.0 2.0 3.9 0.0 0.0 2.6 0.0 0.6 0.0 0.2 0.0 0.3 0.0 0.3 2.3 4.6 4.4 0.1 2.7 0.0 0.6 0.1 0.0 0.3 CRTAP "CASP, LEPREL3, P3H5" ENSG00000170275 "Cartilage associated protein" O75718 3 33114014-33147773 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 377.6" "Group enriched" "Detected in all" 5 "dendritic cells: 306.9;monocytes: 377.6" "Cell line enhanced" "Detected in all" "ASC diff: 795.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043598, HPA044150" Approved Approved "Intermediate filaments,Actin filaments,Cytosol" "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Intermediate filaments, Actin filaments, Cytosol" "HPA043598: AB_10960991, HPA044150: AB_10959594" "unprognostic (5.29e-2)" "unprognostic (2.64e-1)" "unprognostic (2.13e-1)" "unprognostic (1.85e-3)" "unprognostic (7.36e-2)" "unprognostic (4.73e-3)" "unprognostic (4.28e-2)" "unprognostic (1.87e-1)" "unprognostic (9.97e-2)" "unprognostic (4.62e-2)" "unprognostic (3.70e-1)" "unprognostic (1.40e-1)" "unprognostic (2.10e-1)" "unprognostic (1.41e-1)" "unprognostic (1.79e-1)" "unprognostic (9.93e-2)" "unprognostic (1.28e-3)" 157.2 106.5 65.2 38.7 69.2 43.2 123.9 51.9 54.8 211.2 52.9 145.1 35.0 170.1 57.1 58.7 138.3 80.5 83.9 49.6 64.9 67.9 44.6 92.3 37.3 65.2 62.4 131.4 36.0 45.7 22.8 69.9 63.9 90.7 51.6 19.3 54.0 106.5 54.4 84.1 65.6 115.0 67.5 48.2 78.9 25.0 65.3 23.7 77.2 68.9 38.1 142.7 135.8 69.5 64.1 123.3 37.8 119.2 795.0 516.6 219.0 136.1 294.0 160.6 151.9 42.1 35.1 44.4 147.6 259.3 129.9 80.2 68.0 103.9 115.5 110.1 106.0 69.2 87.6 43.7 237.4 45.4 54.8 415.3 208.5 145.0 183.2 311.7 172.0 27.0 60.3 82.1 164.6 54.7 16.5 46.3 45.5 67.5 165.7 59.4 111.0 86.1 127.8 42.0 7.9 61.0 92.0 79.8 201.1 87.3 85.9 109.3 113.0 209.1 89.1 115.4 145.9 59.0 214.3 6.7 164.3 89.7 117.1 13.4 377.6 28.5 35.8 147.7 52.5 39.9 51.4 40.2 306.9 39.2 29.2 27.8 30.5 42.1 46.0 82.5 74.0 200.5 65.2 69.2 51.9 54.8 49.6 64.9 65.2 62.4 63.9 67.5 65.3 69.5 74.0 9.6 42.8 15.3 29.0 60.4 41.1 39.5 150.8 17.9 32.7 43.7 34.7 25.8 22.0 38.6 8.4 49.0 37.1 14.8 11.7 25.0 1.2 17.4 135.7 72.7 6.0 46.0 10.0 32.0 81.6 142.3 29.0 31.2 48.1 58.4 122.4 53.2 107.0 35.3 14.5 26.0 10.2 181.1 91.1 6.3 142.9 108.6 80.0 10.3 134.1 15.9 22.6 17.1 11.6 18.4 16.3 144.8 58.1 24.5 24.4 52.7 6.8 10.1 111.7 78.4 120.9 1.6 15.9 95.1 46.7 28.0 26.5 89.9 36.1 30.0 CTPS1 "CTPS, GATD5" ENSG00000171793 "CTP synthase 1" P17812 1 40979688-41012565 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Pyrimidine biosynthesis" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 73.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017111, HPA051322" Enhanced Approved "Actin filaments,Cytosol" NA Yes 150000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Cytosol "Actin filaments" "CAB017111: , HPA051322: AB_2681441" "unprognostic (6.60e-2)" "unprognostic (4.44e-2)" "unprognostic (3.21e-2)" "unprognostic (2.00e-3)" "unprognostic (2.14e-1)" "unprognostic (8.37e-2)" "unprognostic (1.42e-2)" "unprognostic (9.72e-3)" "unprognostic (1.94e-3)" "unprognostic (1.01e-1)" "unprognostic (2.04e-2)" "unprognostic (8.93e-3)" "unprognostic (1.09e-1)" "unprognostic (8.21e-3)" "unprognostic (1.34e-1)" "unprognostic (4.49e-1)" "unprognostic (1.89e-2)" 9.1 8.1 4.8 11.1 4.7 6.8 6.7 4.0 5.8 9.3 7.9 8.7 4.4 23.6 5.7 14.9 11.1 10.6 5.3 4.9 5.3 12.4 73.4 7.6 12.4 4.6 4.9 3.4 4.7 47.6 0.0 7.8 5.8 13.5 12.0 2.4 50.6 24.8 7.7 4.6 8.4 51.9 4.7 5.0 4.1 14.7 4.9 17.3 4.8 7.6 17.8 17.7 0.3 5.0 77.8 68.5 95.3 60.5 22.9 30.9 138.5 138.8 57.0 141.2 92.0 131.5 66.6 149.8 55.6 61.7 39.4 38.6 91.5 97.0 139.5 66.5 78.0 87.3 72.3 43.3 87.8 128.0 56.8 34.0 49.2 148.5 103.0 23.0 64.1 102.2 84.7 51.5 99.4 42.9 125.0 38.1 126.8 66.4 81.3 100.9 120.0 93.7 71.4 69.4 118.4 61.7 79.2 77.7 33.9 90.8 30.1 152.9 53.5 78.2 119.6 61.7 167.2 36.8 50.8 134.5 59.8 84.5 97.4 0.0 3.5 0.0 3.6 6.5 5.7 5.2 4.1 4.3 11.0 4.0 3.7 6.1 0.0 6.9 5.9 11.9 6.3 3.4 4.8 4.7 4.0 5.8 4.9 5.3 4.6 4.9 5.8 4.7 4.9 5.0 5.4 6.4 18.4 4.9 10.9 8.0 14.3 9.1 9.6 12.5 4.6 4.7 5.7 21.5 7.0 5.5 6.2 15.4 26.4 2.2 1.9 19.2 32.4 4.7 10.8 8.5 3.0 22.5 14.1 17.2 26.4 8.7 7.1 7.3 1.3 15.8 2.2 29.0 11.0 11.8 18.7 3.4 6.1 2.8 6.2 27.9 10.8 6.8 1.8 7.5 8.7 5.4 7.2 7.1 10.3 19.3 1.1 24.8 15.1 19.3 25.2 12.8 2.8 4.3 39.5 9.3 17.5 11.1 40.6 11.8 7.4 5.6 9.9 20.7 5.8 7.3 CYP20A1 CYP-M ENSG00000119004 "Cytochrome P450 family 20 subfamily A member 1" Q6UW02 2 203238977-203306026 "Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA055872, HPA058461" Uncertain Uncertain "Nucleoplasm,Plasma membrane,Cell Junctions,Actin filaments" No No "Cluster 24: B-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Cell Junctions, Actin filaments" Nucleoplasm "HPA055872: AB_2682951, HPA058461: AB_2683725" "unprognostic (4.72e-2)" "unprognostic (2.06e-2)" "unprognostic (1.20e-2)" "unprognostic (2.14e-2)" "unprognostic (1.42e-1)" "unprognostic (3.06e-2)" "unprognostic (5.21e-2)" "unprognostic (2.58e-2)" "unprognostic (4.21e-2)" "unprognostic (2.62e-2)" "unprognostic (4.53e-2)" "unprognostic (4.42e-2)" "unprognostic (7.64e-3)" "unprognostic (9.39e-2)" "unprognostic (2.18e-1)" "unprognostic (1.23e-2)" "unprognostic (1.95e-3)" 3.1 3.2 3.1 2.1 4.3 2.2 2.4 4.1 3.4 2.7 4.2 3.6 2.1 2.3 2.4 2.4 1.9 3.2 1.7 2.7 3.0 6.1 4.6 3.5 3.9 4.5 3.8 3.8 3.1 2.9 0.9 3.4 3.8 3.5 3.2 1.7 2.3 2.1 2.6 3.8 2.6 3.2 2.9 3.7 3.7 2.9 4.2 2.2 8.0 1.3 2.9 3.2 1.0 5.7 2.8 4.7 2.9 2.9 12.1 2.9 2.5 5.0 3.3 2.4 1.7 9.1 5.2 1.9 3.8 4.8 4.4 4.0 1.9 2.7 4.6 2.9 1.0 6.1 3.0 3.5 7.2 6.4 3.3 5.5 2.2 5.7 4.9 2.1 6.4 2.8 8.0 9.9 5.1 4.2 4.3 3.7 7.7 2.3 4.2 3.5 3.7 4.5 3.2 9.2 2.0 2.2 0.4 4.0 5.5 3.3 2.7 4.8 8.5 8.4 2.5 4.0 4.1 5.2 4.4 2.3 6.4 2.8 3.6 5.7 5.2 2.1 6.5 5.6 7.1 6.1 8.0 5.9 2.3 9.6 5.9 3.5 3.0 4.9 6.5 7.4 8.0 4.3 3.1 4.3 4.1 3.4 2.7 3.0 4.5 3.8 3.8 2.9 4.2 5.7 41.2 16.0 33.2 24.2 55.5 12.4 41.6 20.2 29.6 42.0 17.1 17.8 33.6 50.1 33.8 16.5 58.4 33.4 55.8 40.3 11.7 18.3 96.6 24.2 33.6 40.5 45.4 45.5 12.1 20.3 23.0 49.0 53.0 23.7 29.1 65.4 88.2 50.4 37.9 50.5 20.5 33.0 22.4 38.1 22.5 21.9 123.0 35.8 7.2 34.7 44.5 32.4 74.2 24.1 39.1 15.2 30.6 83.8 51.7 33.6 30.8 26.2 23.5 70.5 65.7 76.6 45.7 104.5 64.1 25.4 13.4 40.8 54.4 59.7 32.8 28.7 DBN1 D0S117E ENSG00000113758 "Drebrin 1" Q16643 5 177456608-177474401 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 87.1;Pancreatic endocrine cells: 64.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 5.8;granulocytes: 9.4;T-cells: 14.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051452, HPA056940" Enhanced Supported Supported "Plasma membrane,Actin filaments" NA NA 2000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Actin filaments" "HPA051452: AB_2681489, HPA056940: AB_2683279" "unprognostic (3.81e-2)" "unprognostic (6.60e-3)" "unprognostic (2.88e-2)" "unprognostic (7.57e-3)" "unprognostic (9.32e-2)" "unprognostic (5.68e-2)" "unprognostic (2.01e-3)" "unprognostic (4.29e-2)" "unprognostic (1.73e-2)" "unprognostic (7.92e-2)" "unprognostic (2.94e-2)" "unprognostic (3.64e-1)" "prognostic favorable (8.28e-4)" "unprognostic (1.53e-1)" "unprognostic (4.56e-2)" "unprognostic (1.05e-1)" "unprognostic (1.76e-3)" 59.4 9.3 44.8 17.6 52.5 6.4 36.5 19.3 71.7 59.7 18.6 67.6 9.5 84.4 10.2 30.9 44.7 24.4 39.7 70.1 45.4 52.0 4.0 24.7 9.0 33.8 25.4 34.8 16.9 17.1 45.8 7.1 32.3 29.7 5.9 5.5 33.1 23.9 27.6 36.6 25.0 28.6 24.0 14.2 47.4 27.0 39.7 14.6 33.4 9.0 4.4 61.0 33.1 35.5 17.4 56.1 182.0 319.1 42.4 66.2 56.5 198.6 50.3 113.4 94.5 193.9 59.0 0.3 139.5 155.1 39.0 27.0 80.9 144.0 53.6 5.2 70.4 111.6 72.9 82.0 149.3 43.0 20.5 87.1 37.1 127.3 38.0 113.3 189.4 131.4 54.0 26.0 84.2 25.1 115.1 63.8 264.1 5.7 123.4 338.1 197.2 34.5 85.3 23.7 213.7 289.8 67.0 28.8 111.5 58.4 78.7 42.6 298.6 126.7 169.3 28.2 94.9 6.3 3.1 177.5 53.2 40.5 80.5 9.4 1.4 1.1 10.3 0.8 14.0 0.3 0.3 7.2 1.8 0.4 0.4 5.2 3.2 0.3 0.8 5.8 0.2 2.2 44.8 52.5 19.3 71.7 70.1 45.4 33.8 25.4 32.3 24.0 39.7 35.5 44.2 3.2 1.5 8.1 1.2 10.3 13.7 24.6 9.1 7.0 7.6 9.1 5.1 2.8 11.1 9.2 4.2 1.0 4.5 1.4 1.9 87.1 16.9 8.4 44.0 43.2 40.7 4.8 15.7 43.4 2.8 56.1 11.7 18.4 10.8 49.4 20.7 0.0 1.7 42.1 13.0 2.4 40.7 1.8 8.9 41.6 50.1 6.1 8.8 2.8 2.4 13.4 1.0 5.0 1.0 64.5 0.6 41.0 4.0 16.9 0.6 6.3 5.2 4.5 19.7 10.8 43.4 6.5 26.7 20.1 7.2 0.8 10.4 8.1 3.9 7.5 DDC AADC ENSG00000132437 "Dopa decarboxylase" P20711 7 50458436-50565405 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Catecholamine biosynthesis" "Decarboxylase, Lyase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 165.8;kidney: 314.9;retina: 175.6" "Group enriched" "Detected in many" 4 "Enteroendocrine cells: 410.3;Proximal enterocytes: 391.5;Proximal tubular cells: 429.5;Rod photoreceptor cells: 498.9" "Group enriched" "Detected in many" 5 "colorectal cancer: 23.5;liver cancer: 13.4;pancreatic cancer: 6.4;renal cancer: 18.7;stomach cancer: 9.9" "Group enriched" "Detected in many" 9 "midbrain: 86.3;pons: 29.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "CACO-2: 54.5;Hep G2: 49.3;OE19: 83.6;SCLC-21H: 130.9;SH-SY5Y: 135.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "midbrain: 74.5;pons: 29.4" HPA017742 Enhanced Approved "Actin filaments" NA NA 120000 "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Actin filaments" "HPA017742: AB_1847832" "unprognostic (1.04e-1)" "unprognostic (3.68e-2)" "unprognostic (2.57e-2)" "unprognostic (3.49e-5)" "unprognostic (1.17e-1)" "unprognostic (1.03e-1)" "unprognostic (1.28e-1)" "unprognostic (5.15e-2)" "unprognostic (4.69e-2)" "unprognostic (5.44e-2)" "unprognostic (9.36e-3)" "unprognostic (5.24e-2)" "unprognostic (1.76e-3)" "unprognostic (1.60e-1)" "unprognostic (3.55e-1)" "unprognostic (7.65e-2)" "unprognostic (1.16e-1)" 0.5 48.9 0.1 2.3 0.7 0.0 1.0 0.0 0.6 0.0 0.2 36.5 154.8 0.0 9.1 0.1 0.0 0.1 0.0 0.2 2.2 314.9 54.6 2.0 0.1 6.1 86.3 0.8 15.8 0.0 0.0 0.0 29.4 0.6 37.5 175.6 0.0 0.0 0.0 0.1 165.8 1.7 0.0 0.1 18.1 1.5 1.9 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 1.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 54.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.3 0.0 0.0 11.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 83.6 0.0 0.0 0.0 0.7 1.3 0.0 130.9 135.9 0.0 4.4 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.6 0.2 2.2 6.1 86.3 29.4 0.0 1.9 0.2 0.0 0.0 12.2 0.0 2.5 0.0 0.0 0.0 0.0 89.3 0.1 0.1 0.4 2.8 0.6 3.7 41.7 0.0 0.0 34.4 25.4 0.1 6.6 0.1 0.0 1.8 410.3 0.0 0.3 0.9 0.1 0.1 0.0 0.4 0.0 0.0 1.1 67.2 0.1 3.3 0.4 67.8 0.0 1.3 0.0 5.4 0.0 2.5 0.0 0.0 0.0 45.1 0.0 0.0 0.1 0.2 31.8 0.0 0.0 0.3 391.5 429.5 0.0 498.9 0.0 0.0 0.0 4.0 0.4 0.0 0.0 0.1 1.3 0.1 88.7 0.2 DDIT4L "REDD2, Rtp801L" ENSG00000145358 "DNA damage inducible transcript 4 like" Q96D03 4 100185870-100190782 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "skeletal muscle: 323.5;tongue: 106.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 22.0;Distal tubular cells: 21.5;Extravillous trophoblasts: 18.5;Granulosa cells: 23.5;Sertoli cells: 19.7" "Cancer enhanced" "Detected in many" "testis cancer: 19.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 19.3;BJ: 29.6;fHDF/TERT166: 16.2;HSkMC: 14.7;hTERT-RPE1: 32.8;RPTEC TERT1: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050903 Uncertain "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane" "Nucleoplasm, Actin filaments" "HPA050903: " "unprognostic (2.21e-1)" "unprognostic (1.92e-1)" "unprognostic (1.34e-1)" "prognostic favorable (5.77e-4)" "unprognostic (1.66e-3)" "unprognostic (5.92e-2)" "unprognostic (2.72e-2)" "unprognostic (3.12e-1)" "unprognostic (3.21e-1)" "unprognostic (7.18e-2)" "unprognostic (2.59e-1)" "unprognostic (1.41e-1)" "unprognostic (4.47e-2)" "unprognostic (4.82e-3)" "unprognostic (2.09e-2)" "unprognostic (7.53e-5)" "unprognostic (4.99e-3)" 3.1 1.0 7.0 0.6 21.1 0.4 2.2 8.5 11.0 23.0 7.7 2.0 0.3 1.5 1.7 7.7 2.1 0.6 2.3 10.2 7.6 21.8 0.4 0.8 0.5 11.8 8.8 7.7 0.4 0.6 2.0 3.7 11.1 11.2 0.9 1.2 17.4 6.9 323.5 1.1 0.7 1.6 9.1 1.2 0.5 3.0 8.7 1.2 1.1 106.9 0.4 1.2 2.6 8.9 0.0 2.2 8.5 0.0 3.7 19.3 1.2 29.6 2.5 0.5 0.1 0.1 0.9 0.0 0.7 16.2 0.7 0.0 6.2 0.5 0.5 0.0 0.2 0.0 0.5 0.0 0.2 0.0 0.0 14.7 0.1 0.3 1.5 32.8 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 9.7 0.0 0.0 0.6 0.0 0.0 20.5 0.1 0.1 0.1 0.6 1.2 4.0 2.0 0.0 0.1 0.1 0.0 0.0 0.0 2.3 3.9 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 7.0 21.1 8.5 11.0 10.2 7.6 11.8 8.8 11.1 9.1 8.7 8.9 3.8 0.0 0.0 6.2 0.0 2.7 0.2 4.2 1.8 0.1 1.0 0.9 7.3 0.0 1.3 22.0 0.0 1.9 0.4 0.2 21.5 0.1 0.8 0.5 0.3 3.6 0.0 0.0 0.0 0.0 18.5 5.1 1.5 0.9 0.0 23.5 0.0 0.0 12.0 0.0 0.5 0.3 0.0 0.0 3.0 0.4 0.9 0.3 7.2 0.0 0.0 8.6 0.0 0.5 0.0 0.5 0.0 2.2 0.2 1.1 0.0 2.2 0.1 0.2 19.7 7.3 11.9 4.7 0.8 0.9 1.4 4.0 0.6 8.3 0.4 0.3 DDR2 "NTRKR3, TKT, TYRO10" ENSG00000162733 "Discoidin domain receptor tyrosine kinase 2" Q16832 1 162631373-162787405 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Osteogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 89.8;Fibroblasts: 116.5;Leydig cells: 63.0;Peritubular cells: 88.4;Skeletal myocytes: 98.2;Smooth muscle cells: 78.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 233.3;ASC TERT1: 214.4;BJ hTERT+: 163.4;fHDF/TERT166: 137.6;HSkMC: 157.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070112 Approved "Plasma membrane,Actin filaments" Yes No 770000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Actin filaments" "HPA070112: AB_2686229" "unprognostic (4.12e-2)" "unprognostic (2.73e-1)" "unprognostic (6.97e-3)" "unprognostic (4.52e-2)" "unprognostic (1.17e-1)" "unprognostic (8.16e-2)" "unprognostic (1.81e-1)" "unprognostic (1.19e-1)" "unprognostic (6.62e-2)" "unprognostic (2.24e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.73e-7)" "unprognostic (1.56e-3)" "unprognostic (8.26e-3)" "unprognostic (7.57e-2)" "unprognostic (4.10e-3)" 59.8 64.3 13.2 15.8 11.3 0.3 25.2 10.4 9.2 33.7 51.5 54.7 5.8 26.2 13.2 18.1 22.4 23.8 24.1 12.6 24.5 6.4 5.4 14.5 9.1 37.0 22.1 37.4 3.7 2.5 5.4 10.6 31.7 17.3 14.1 5.1 9.8 29.2 4.9 9.7 17.6 42.8 17.8 5.8 20.4 3.9 21.0 3.3 12.9 19.3 6.9 23.2 23.6 25.2 0.3 0.0 0.2 63.2 233.3 214.4 1.0 92.2 163.4 41.5 56.8 0.0 0.2 0.0 0.1 137.6 8.9 0.1 0.3 0.4 54.0 42.9 0.3 0.0 0.4 0.1 103.9 0.2 0.2 157.0 0.4 73.1 2.2 65.8 46.0 0.4 0.6 16.8 36.9 0.1 0.0 0.3 0.4 0.1 0.3 0.1 24.1 0.7 0.2 0.2 0.3 35.4 0.2 0.1 2.9 3.6 0.2 0.3 2.1 58.5 13.8 29.1 12.6 2.6 4.0 0.1 56.3 0.1 62.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 11.3 10.4 9.2 12.6 24.5 37.0 22.1 31.7 17.8 21.0 25.2 23.4 3.2 2.3 53.2 2.5 12.6 3.9 0.8 1.2 3.0 6.0 15.6 31.3 1.5 1.1 0.0 0.0 0.5 1.7 3.2 0.0 0.4 8.9 5.0 89.8 22.3 1.2 0.0 13.1 1.8 0.5 116.5 2.6 8.2 1.3 16.7 30.0 3.5 1.2 0.0 26.2 1.0 0.0 1.9 19.3 7.1 63.0 3.1 23.2 29.0 0.0 16.5 2.1 6.0 5.6 1.8 4.4 88.4 5.6 5.9 1.2 2.1 2.4 3.0 39.5 98.2 78.3 1.0 0.9 2.0 8.7 1.0 2.5 34.2 0.8 4.2 DDX59 "DKFZP564B1023, ZNHIT5" ENSG00000118197 "DEAD-box helicase 59" Q5T1V6 1 200623896-200669907 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047166 Approved Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 50: Non-specific - Ribosome" "Cluster 44: HDLM-2 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Actin filaments" "HPA047166: AB_2679966" "unprognostic (1.99e-1)" "unprognostic (1.60e-1)" "unprognostic (3.44e-2)" "unprognostic (4.87e-2)" "unprognostic (1.18e-2)" "unprognostic (1.13e-1)" "unprognostic (3.05e-2)" "unprognostic (4.83e-2)" "unprognostic (3.40e-3)" "unprognostic (2.43e-3)" "unprognostic (4.16e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (9.02e-4)" "unprognostic (1.62e-1)" "unprognostic (1.65e-1)" "unprognostic (6.66e-2)" "unprognostic (5.98e-2)" 15.4 16.1 13.5 14.2 15.4 33.1 26.5 17.1 18.8 16.2 15.6 14.2 10.2 17.6 20.0 13.5 15.5 12.2 13.3 14.0 14.7 16.4 17.8 14.5 17.0 16.0 15.0 17.6 18.8 15.0 11.3 18.7 17.3 15.2 15.0 17.4 14.4 13.2 32.8 26.2 14.3 14.1 16.3 22.4 12.1 11.0 15.1 22.0 16.2 20.1 16.9 15.0 14.7 17.8 17.5 20.1 22.6 19.0 10.1 17.4 49.9 19.1 17.4 20.5 16.5 6.3 20.2 17.9 9.5 15.7 16.4 16.2 13.0 19.4 14.5 56.8 13.3 13.6 26.4 18.6 20.2 19.5 24.0 18.8 29.1 15.4 41.7 16.7 15.9 24.8 17.4 25.9 20.1 20.0 12.0 29.0 23.8 10.5 16.3 10.1 15.5 34.7 21.9 19.8 13.8 35.7 30.8 31.7 35.6 28.8 27.3 27.3 14.4 17.1 9.5 16.8 20.0 19.5 27.2 23.5 16.3 12.2 30.0 33.3 12.4 24.7 15.1 11.1 12.4 14.9 12.5 13.8 10.6 14.8 12.7 11.8 22.9 16.4 22.0 11.8 19.8 10.2 13.5 15.4 17.1 18.8 14.0 14.7 16.0 15.0 17.3 16.3 15.1 17.8 22.5 19.2 20.1 8.8 19.9 16.2 13.1 16.1 24.5 4.3 10.0 13.2 18.4 7.2 10.6 7.3 2.1 22.2 14.6 9.8 15.6 8.8 2.4 14.6 13.3 16.7 1.2 10.5 4.5 8.2 28.0 14.9 6.6 12.8 20.8 7.1 14.3 7.3 13.0 6.7 6.1 11.0 14.2 12.0 13.0 1.1 8.1 16.1 5.4 8.4 18.5 8.3 25.7 19.1 10.3 8.8 7.9 13.5 13.1 12.0 8.0 11.6 10.8 6.7 0.0 22.8 15.7 14.2 20.0 12.9 15.6 43.8 18.9 9.3 8.5 11.1 DHDH HUM2DD ENSG00000104808 "Dihydrodiol dehydrogenase" Q9UQ10 19 48933699-48944969 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 17.3;kidney: 18.0" "Group enriched" "Detected in many" 11 "Proximal enterocytes: 213.7;Proximal tubular cells: 77.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.2" "Group enriched" "Detected in many" 33 "granulocytes: 4.2;T-cells: 2.3" "Cell line enhanced" "Detected in some" "JURKAT: 3.2;U-266/70: 3.2;U-266/84: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044131 Approved Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Actin filaments" "HPA044131: AB_10966968" "unprognostic (1.54e-1)" "unprognostic (2.72e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (9.91e-4)" "unprognostic (3.33e-3)" "unprognostic (1.45e-1)" "unprognostic (5.81e-6)" "unprognostic (1.56e-2)" "unprognostic (5.88e-2)" "unprognostic (4.96e-2)" "unprognostic (3.30e-2)" "unprognostic (5.08e-2)" "prognostic favorable (3.15e-4)" "unprognostic (2.93e-2)" "unprognostic (1.23e-1)" "unprognostic (1.67e-1)" "unprognostic (1.54e-1)" 0.2 0.4 1.6 0.0 1.6 0.1 0.2 1.9 3.3 0.3 1.0 0.3 10.5 0.1 0.0 0.8 0.3 0.2 0.1 1.7 1.7 18.0 0.4 1.1 0.2 1.2 1.3 0.6 0.4 0.5 1.8 1.3 1.2 3.2 0.0 1.7 0.4 0.1 0.2 0.2 17.3 0.0 1.3 1.7 0.7 1.9 2.7 0.1 0.1 0.0 0.2 0.3 0.4 1.6 1.4 0.0 0.1 0.7 0.4 0.3 0.5 0.0 0.2 0.2 0.7 1.4 1.1 0.0 0.2 0.0 0.9 0.4 0.5 1.0 0.4 0.5 1.1 2.0 0.5 0.5 0.0 0.0 0.4 0.2 0.1 0.5 0.0 0.3 0.0 3.2 0.7 0.2 0.0 0.3 0.0 0.1 0.3 2.1 0.9 0.7 0.1 1.0 0.1 0.4 2.1 1.1 0.2 0.1 0.5 0.1 1.0 0.0 0.0 0.0 0.8 0.3 0.0 3.2 2.8 0.8 0.7 0.0 0.2 4.2 0.0 0.5 0.7 0.0 0.4 0.0 0.8 0.3 0.0 0.0 2.3 1.5 0.0 0.0 0.0 0.0 0.6 0.2 1.6 1.6 1.9 3.3 1.7 1.7 1.2 1.3 1.2 1.3 2.7 1.6 0.5 3.2 6.4 1.0 1.0 0.8 2.4 3.3 2.2 2.4 1.0 3.4 0.7 1.5 4.6 3.7 0.0 0.2 0.4 1.5 9.8 2.2 0.7 0.3 0.5 0.8 0.0 0.4 1.0 0.4 0.2 0.5 4.1 0.8 1.3 0.1 0.0 0.0 12.9 0.0 1.2 5.0 2.0 0.8 0.0 2.4 0.0 1.7 0.0 0.0 0.0 1.6 0.0 0.0 0.5 1.5 3.6 0.0 0.0 3.5 213.7 77.8 0.5 4.5 0.0 1.2 0.4 0.0 0.8 3.1 0.1 0.1 0.6 0.4 2.7 3.2 DMWD "D19S593E, DMR-N9, gene59" ENSG00000185800 "DM1 locus, WD repeat containing" Q09019 19 45782947-45792845 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 60.5;Late spermatids: 57.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068172, HPA069843" Approved Approved "Plasma membrane,Actin filaments" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Actin filaments" "HPA068172: AB_2685964, HPA069843: AB_2686212" "unprognostic (6.49e-2)" "unprognostic (3.35e-1)" "unprognostic (1.03e-2)" "unprognostic (1.65e-3)" "unprognostic (3.10e-2)" "unprognostic (2.39e-1)" "prognostic unfavorable (1.47e-4)" "unprognostic (5.11e-3)" "unprognostic (7.61e-2)" "unprognostic (7.26e-3)" "unprognostic (1.31e-2)" "unprognostic (2.16e-1)" "unprognostic (1.81e-1)" "unprognostic (1.85e-1)" "unprognostic (1.97e-1)" "unprognostic (1.18e-2)" "unprognostic (4.59e-2)" 24.6 19.1 27.7 12.3 23.4 7.3 23.0 10.5 31.7 29.1 10.8 40.3 9.7 39.6 6.7 18.2 29.4 11.8 43.1 30.0 18.6 18.7 10.2 22.6 11.2 17.5 19.9 29.1 18.1 10.3 29.6 15.0 15.1 25.2 7.4 11.9 17.1 12.2 44.0 15.5 18.3 14.8 8.9 17.0 25.0 36.5 20.2 10.3 23.1 20.1 7.1 30.6 23.2 14.5 31.6 34.3 30.4 21.2 18.1 22.9 23.3 26.9 18.8 23.5 21.2 20.6 17.1 13.2 15.4 30.4 28.8 23.4 16.1 13.4 12.3 38.6 30.0 11.4 37.3 18.2 22.4 1.4 17.6 21.5 16.2 22.0 31.2 26.7 20.3 8.3 28.2 28.9 18.6 25.8 16.0 9.0 13.8 20.6 22.2 16.3 11.0 14.5 14.6 29.7 30.4 33.6 28.9 22.2 19.5 13.4 19.4 7.7 43.3 27.0 26.6 18.1 40.7 41.1 27.4 15.0 28.1 2.1 31.8 0.6 0.2 0.2 1.4 0.6 1.1 0.6 1.2 1.1 0.2 1.4 0.4 0.8 0.6 1.8 0.8 0.2 0.7 0.3 27.7 23.4 10.5 31.7 30.0 18.6 17.5 19.9 15.1 8.9 20.2 14.5 18.8 6.4 4.7 8.1 6.9 8.4 13.9 4.5 2.2 34.5 11.8 9.8 28.5 10.0 4.4 9.2 60.5 7.3 10.6 10.4 5.9 7.3 17.2 12.4 18.9 16.2 26.3 9.3 8.1 10.6 9.6 15.3 6.1 11.2 11.4 23.3 20.0 4.6 2.0 52.2 7.5 7.9 10.2 4.8 11.4 57.7 17.1 2.6 5.4 5.6 0.9 23.3 14.4 10.1 5.8 13.8 7.2 17.0 6.8 11.5 5.6 7.1 8.9 41.2 13.1 24.5 19.0 10.8 15.7 4.6 7.0 5.5 9.0 20.6 8.1 11.5 EFR3B "FLJ37871, KIAA0953" ENSG00000084710 "EFR3 homolog B" Q9Y2G0 2 25042076-25159135 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.1;skeletal muscle: 20.0" "Cell type enhanced" "Detected in many" "Astrocytes: 127.0;Excitatory neurons: 58.5;Inhibitory neurons: 110.7;Late spermatids: 46.0;Microglial cells: 54.4;Oligodendrocytes: 51.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.3" "Cell line enhanced" "Detected in many" "AN3-CA: 10.3;BEWO: 12.0;SH-SY5Y: 10.7;SK-BR-3: 18.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038089, HPA071831" Uncertain Supported "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 10: Brain - Neuronal signaling" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Actin filaments, Cytosol" "HPA038089: AB_10672618, HPA071831: " "unprognostic (9.31e-2)" "unprognostic (3.92e-1)" "unprognostic (2.10e-1)" "unprognostic (2.23e-1)" "unprognostic (1.90e-1)" "unprognostic (2.44e-2)" "unprognostic (1.24e-3)" "unprognostic (3.82e-1)" "unprognostic (3.42e-1)" "unprognostic (1.32e-2)" "unprognostic (4.49e-6)" "unprognostic (4.83e-2)" "unprognostic (4.43e-2)" "unprognostic (1.89e-1)" "unprognostic (2.46e-1)" "unprognostic (1.13e-1)" "unprognostic (1.55e-1)" 0.8 1.6 23.0 0.6 53.1 0.3 0.5 22.4 29.5 0.5 0.0 1.1 0.4 0.7 5.1 0.3 0.6 0.5 4.5 51.7 19.0 1.3 0.2 2.5 0.3 45.3 24.0 0.8 0.4 3.9 9.3 1.7 47.5 0.5 0.6 11.0 0.3 0.8 20.0 0.6 0.5 1.2 9.8 3.4 0.9 2.5 27.7 0.3 3.4 3.8 0.2 0.5 0.4 12.1 0.2 8.3 9.5 10.3 0.5 0.1 12.0 1.0 0.2 0.5 0.1 6.7 0.4 0.1 0.6 1.4 3.3 0.6 7.5 0.0 0.1 1.6 1.8 1.6 0.3 0.6 0.0 0.1 0.8 0.1 0.0 2.3 0.1 0.7 0.3 0.2 0.1 0.4 0.2 0.9 0.2 0.5 1.9 0.1 6.6 0.8 9.1 0.3 0.1 0.3 4.0 10.7 1.2 18.0 5.9 5.3 0.9 0.1 0.5 0.5 2.7 4.1 2.0 0.7 0.9 0.1 7.3 0.1 1.9 1.3 0.1 0.3 0.2 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.4 0.2 0.1 0.1 0.0 0.0 23.0 53.1 22.4 29.5 51.7 19.0 45.3 24.0 47.5 9.8 27.7 12.1 3.1 28.9 1.1 127.0 0.0 0.0 0.8 0.0 0.0 9.9 0.3 1.0 9.7 0.0 0.0 9.2 22.9 0.1 0.1 0.7 0.0 0.3 20.6 1.3 0.3 6.7 3.6 0.0 58.5 0.8 0.2 1.0 0.0 0.3 0.0 1.1 2.9 0.0 0.9 5.0 110.7 0.1 0.0 0.0 0.3 46.0 1.2 0.1 0.0 54.4 0.0 22.0 0.0 19.6 51.2 0.7 0.0 2.6 0.1 0.6 0.5 0.1 0.0 10.7 0.0 1.6 1.4 2.4 2.2 0.0 0.1 0.1 0.1 0.2 0.3 0.4 EIF2B4 "DKFZP586J0119, EIF-2B, EIF2B, EIF2Bdelta" ENSG00000115211 "Eukaryotic translation initiation factor 2B subunit delta" Q9UI10 2 27364352-27370457 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 196.4;Late spermatids: 299.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032234, HPA039993, HPA068855" Approved Approved "Nuclear membrane,Actin filaments" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear membrane" "Actin filaments" "CAB032234: AB_668909, HPA039993: AB_2676790, HPA068855: " "unprognostic (2.26e-2)" "unprognostic (1.41e-1)" "unprognostic (3.00e-1)" "unprognostic (7.55e-2)" "unprognostic (2.37e-1)" "unprognostic (4.63e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (3.64e-2)" "unprognostic (2.18e-1)" "unprognostic (3.56e-3)" "unprognostic (1.11e-1)" "unprognostic (2.68e-1)" "prognostic unfavorable (5.46e-8)" "unprognostic (1.79e-1)" "unprognostic (1.70e-1)" "unprognostic (8.76e-2)" "unprognostic (1.67e-2)" 21.4 24.8 23.3 15.2 24.3 10.7 20.7 24.0 23.8 21.3 22.5 31.7 14.6 21.0 16.9 27.8 20.3 13.4 28.0 23.2 23.7 18.2 21.5 18.1 17.2 24.4 24.3 19.8 31.4 20.4 20.3 18.8 24.0 25.4 18.4 19.3 24.6 20.8 51.8 29.3 18.4 22.8 23.2 18.6 24.7 38.1 24.4 18.9 18.1 35.2 22.9 24.1 21.4 24.1 38.7 59.8 44.3 34.6 58.4 42.7 48.4 41.0 43.7 55.7 37.3 89.2 16.9 49.7 38.7 48.7 46.6 27.6 62.5 50.8 36.2 37.4 40.7 61.7 39.3 104.5 51.1 58.2 23.0 41.3 51.1 69.2 51.6 40.4 53.3 37.2 59.5 24.9 53.0 35.2 28.8 61.7 49.1 59.8 38.9 52.9 69.9 43.2 50.0 32.7 34.3 37.4 34.1 53.8 42.6 39.6 31.3 23.4 52.8 40.1 47.0 35.4 49.7 50.9 65.7 74.7 33.9 47.9 38.6 56.6 53.9 38.8 32.1 48.1 44.6 31.1 31.6 32.6 52.5 25.3 30.2 32.9 7.7 30.8 52.2 38.6 43.8 43.2 23.3 24.3 24.0 23.8 23.2 23.7 24.4 24.3 24.0 23.2 24.4 24.1 19.9 12.8 14.8 9.8 17.5 35.9 18.9 32.0 15.4 22.6 28.0 18.7 33.0 14.3 27.0 22.0 66.7 40.9 27.8 23.4 19.6 29.0 196.4 22.3 23.9 19.9 24.0 8.2 6.6 33.4 25.0 24.6 14.8 17.6 31.6 16.9 25.7 34.4 24.3 10.1 6.5 24.8 28.5 20.7 28.0 299.6 23.3 16.5 23.2 2.8 29.5 23.2 16.5 6.0 8.8 26.7 27.1 24.8 28.4 21.2 23.0 27.6 24.9 58.9 19.7 17.0 34.9 71.5 38.9 14.5 34.8 46.1 24.3 23.8 20.5 14.4 ENPP2 "ATX, PD-IALPHA, PDNP2" ENSG00000136960 "Ectonucleotide pyrophosphatase/phosphodiesterase 2" Q13822 8 119557086-119673453 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Lipid degradation, Lipid metabolism" Hydrolase "Cancer-related genes, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 383.3;choroid plexus: 753.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1041.6" "Cancer enhanced" "Detected in all" "renal cancer: 46.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 53.8" "Lineage enriched" "Detected in many" 8 "granulocytes: 53.8" "Cell line enhanced" "Detected in many" "AF22: 111.4;ASC diff: 147.7;ASC TERT1: 312.5;BJ: 103.2;BJ hTERT+: 188.9;fHDF/TERT166: 124.2;HSkMC: 144.7;U-2197: 108.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023700, HPA053652" Approved Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" NA NA 1200000000 "Cluster 46: Basophils - DNA binding" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Golgi apparatus" "Actin filaments" "HPA023700: AB_1848170, HPA053652: AB_2682218" "unprognostic (1.17e-2)" "unprognostic (6.29e-2)" "unprognostic (3.63e-2)" "unprognostic (3.93e-2)" "unprognostic (1.23e-1)" "unprognostic (1.37e-1)" "unprognostic (9.70e-3)" "unprognostic (7.14e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "prognostic favorable (2.07e-5)" "unprognostic (5.54e-2)" "unprognostic (3.14e-1)" "unprognostic (2.37e-1)" "unprognostic (5.18e-2)" "unprognostic (2.37e-2)" "unprognostic (1.50e-1)" 104.7 46.7 98.9 62.0 208.4 2.7 89.7 188.1 150.1 73.6 753.4 32.6 67.5 139.2 20.2 9.0 55.7 39.9 9.9 111.0 133.0 76.6 28.5 42.7 109.8 246.2 164.4 15.2 15.9 20.2 11.8 252.3 244.4 26.4 32.3 6.9 9.9 27.3 8.9 17.5 45.8 85.1 147.8 51.4 26.9 31.3 153.7 20.8 10.8 23.9 85.8 45.1 18.1 383.3 0.0 0.0 111.4 0.0 147.7 312.5 0.4 103.2 188.9 43.9 42.1 0.0 0.0 0.1 1.3 124.2 0.1 0.3 2.3 0.0 31.3 8.7 3.4 0.0 0.2 3.1 67.0 0.0 0.5 144.7 1.3 89.3 4.3 0.6 0.5 0.1 0.1 18.1 2.5 0.0 0.1 0.7 4.4 0.0 0.5 0.1 0.1 0.6 0.3 0.0 1.1 2.2 0.1 0.4 0.2 4.2 0.1 0.0 0.0 89.6 1.9 108.6 0.9 0.9 0.0 0.0 75.0 0.8 2.4 53.8 0.2 9.5 0.0 0.1 0.1 0.4 0.5 0.0 1.0 0.1 3.0 1.1 0.5 0.4 0.2 6.8 0.0 0.6 98.9 208.4 188.1 150.1 111.0 133.0 246.2 164.4 244.4 147.8 153.7 383.3 231.4 12.8 3.6 2.0 1.8 10.6 0.5 0.0 19.9 1.9 2.1 2.8 1.8 35.8 0.6 1.8 0.0 5.2 4.9 0.3 1.9 0.1 83.9 12.7 8.8 79.9 54.0 0.8 2.5 0.0 2.2 76.9 3.6 1.4 6.3 0.4 31.1 0.8 65.8 0.0 4.2 3.3 0.0 18.6 14.9 9.5 3.1 16.2 46.2 6.5 0.1 6.4 0.0 16.6 1041.6 0.7 2.6 3.4 1.9 0.1 4.2 47.6 3.7 1.2 0.0 3.1 9.6 1.7 0.4 7.8 5.3 6.4 1.7 1.1 2.8 1.4 EPHA3 "ETK, ETK1, HEK, HEK4, TYRO4" ENSG00000044524 "EPH receptor A3" P29320 3 89107621-89482134 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 31.5" "Group enriched" "Detected in some" 4 "Excitatory neurons: 70.6;Inhibitory neurons: 106.6;Microglial cells: 103.0;Oligodendrocytes: 48.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "AF22: 197.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB010462, HPA069390" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear membrane, Plasma membrane, Cytosol" "Nucleoplasm, Actin filaments" "CAB010462: AB_2099218, HPA069390: " "unprognostic (1.48e-3)" "unprognostic (2.30e-2)" "unprognostic (4.95e-2)" "unprognostic (1.90e-1)" "unprognostic (2.96e-2)" "unprognostic (1.47e-2)" "unprognostic (2.03e-1)" "unprognostic (9.10e-3)" "unprognostic (1.24e-3)" "unprognostic (7.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (3.28e-7)" "unprognostic (3.63e-2)" "unprognostic (1.88e-2)" "unprognostic (4.05e-2)" "unprognostic (1.20e-2)" 5.4 1.0 2.1 1.8 1.3 0.0 2.3 0.2 3.8 12.3 0.1 3.8 2.3 5.5 0.2 3.2 1.3 18.8 8.2 2.2 0.7 1.3 4.9 2.4 3.6 3.3 0.9 4.1 2.1 1.0 0.9 20.1 4.0 31.5 6.2 8.0 2.2 7.1 0.8 0.7 2.4 7.9 0.8 0.9 2.5 1.0 1.7 1.0 11.0 6.3 3.2 14.3 6.4 2.2 0.0 0.0 197.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 11.2 0.2 0.7 0.0 2.4 0.0 0.0 11.8 0.0 0.0 1.7 2.0 0.0 3.9 0.0 0.0 0.6 0.0 2.5 0.1 0.3 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.1 0.0 0.5 0.1 0.1 36.1 0.1 0.0 0.0 1.7 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.3 0.2 3.8 2.2 0.7 3.3 0.9 4.0 0.8 1.7 2.2 2.2 0.0 0.0 5.5 0.0 0.5 0.3 0.0 0.6 6.4 0.0 0.1 2.4 0.0 0.0 0.0 2.1 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.5 1.8 0.0 0.0 70.6 0.0 0.1 18.1 0.5 0.0 0.0 0.0 1.1 0.0 0.1 20.2 106.6 0.0 0.0 0.0 0.7 1.6 2.1 0.1 0.0 103.0 0.0 4.7 0.0 2.5 48.0 0.0 0.0 8.2 0.0 0.1 0.0 0.0 0.0 18.7 6.6 0.7 19.2 0.1 0.0 0.3 0.3 0.5 0.2 1.3 0.0 0.1 EQTN "AFAF, C9orf11, equatorin, SPACA8" ENSG00000120160 Equatorin Q9NQ60 9 27284654-27297150 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "testis: 37.8" "Cell type enriched" "Detected in some" 10 "Early spermatids: 739.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015089, HPA015504" Enhanced Approved "Plasma membrane,Actin filaments" "Secreted in male reproductive system" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane, Actin filaments" "HPA015089: AB_1845795, HPA015504: AB_2067598" "unprognostic (7.83e-2)" "unprognostic (1.55e-1)" "unprognostic (5.64e-2)" "unprognostic (8.12e-3)" "unprognostic (1.34e-3)" "unprognostic (4.41e-2)" "unprognostic (3.21e-1)" "unprognostic (1.06e-1)" "unprognostic (4.32e-1)" "unprognostic (1.89e-1)" "unprognostic (5.67e-2)" "unprognostic (1.14e-1)" "unprognostic (4.59e-2)" "unprognostic (8.46e-2)" "unprognostic (3.90e-2)" "unprognostic (1.42e-1)" 0.2 0.0 0.4 0.0 1.2 0.0 0.2 0.8 0.6 0.2 0.2 0.3 0.4 0.2 0.5 0.0 0.2 0.0 0.0 0.2 0.4 0.2 0.0 0.3 0.2 1.5 0.9 0.5 0.4 0.0 0.0 0.0 1.3 0.1 0.3 0.1 0.0 0.1 0.1 0.2 0.3 0.0 0.8 0.2 0.2 37.8 1.6 0.0 0.2 0.1 0.0 0.1 0.1 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.2 0.8 0.6 0.2 0.4 1.5 0.9 1.3 0.8 1.6 2.0 0.0 0.0 0.0 1.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 739.3 0.2 0.2 0.2 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 67.8 5.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.7 0.0 0.2 0.6 0.2 0.0 0.0 0.0 0.0 0.2 16.2 2.4 0.0 0.3 0.1 0.0 0.1 0.2 0.1 ERBB3 "HER3, LCCS2" ENSG00000065361 "Erb-b2 receptor tyrosine kinase 3" P21860 12 56076799-56103505 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 254.3;Oligodendrocytes: 187.0;Paneth cells: 184.6;Proximal enterocytes: 240.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 2.4;neutrophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.4" "Cell line enhanced" "Detected in many" "Hep G2: 116.4;OE19: 119.1;RT4: 89.7;SK-BR-3: 106.5;SK-MEL-30: 149.5;T-47d: 122.2;WM-115: 153.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025331, HPA045396, HPA070524" Approved Supported "Plasma membrane,Actin filaments" "Secreted - unknown location" NA NA 450000 "Cluster 17: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Actin filaments" "CAB025331: , HPA045396: AB_2679312, HPA070524: " "unprognostic (2.97e-1)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (8.97e-2)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (2.31e-3)" "unprognostic (2.66e-2)" "unprognostic (9.89e-2)" "unprognostic (4.30e-2)" "unprognostic (4.76e-3)" "unprognostic (5.77e-2)" "unprognostic (1.06e-2)" "unprognostic (4.56e-2)" "unprognostic (1.57e-1)" "unprognostic (6.72e-3)" "unprognostic (2.07e-2)" 2.4 2.6 34.4 8.0 69.2 0.9 56.5 45.9 62.0 20.9 10.9 62.9 88.5 5.5 12.3 82.0 12.1 30.6 9.0 39.2 43.1 36.2 98.6 29.3 0.6 59.4 54.4 1.6 57.0 23.8 2.4 13.0 54.7 37.8 64.1 1.3 83.0 18.2 2.4 75.7 82.5 3.8 36.2 0.6 74.7 2.3 55.9 1.0 9.4 1.7 12.5 21.8 44.2 104.9 39.8 2.1 3.2 1.4 0.2 0.1 63.2 3.9 7.2 4.5 4.1 20.4 70.4 0.2 0.8 1.0 0.6 32.2 5.0 7.7 2.3 0.7 3.0 0.1 1.1 116.4 0.1 0.1 0.5 1.3 9.3 0.7 0.3 0.7 0.1 0.8 2.6 1.0 0.4 71.6 0.4 1.3 10.4 119.1 1.9 0.4 7.4 2.1 7.9 89.7 3.3 1.3 2.6 106.5 149.5 9.1 122.2 0.7 0.3 0.5 4.0 1.9 0.5 0.9 0.6 0.6 0.4 0.3 153.4 2.4 0.1 0.3 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.4 1.0 0.4 0.2 0.2 0.3 0.1 34.4 69.2 45.9 62.0 39.2 43.1 59.4 54.4 54.7 36.2 55.9 104.9 0.8 118.6 81.0 1.0 1.5 18.2 15.3 21.6 19.4 1.5 106.4 47.8 1.9 171.6 74.6 35.0 2.1 52.6 2.0 254.3 1.9 60.1 1.3 36.1 10.9 2.7 93.1 2.7 0.7 88.1 84.6 4.5 96.4 95.9 1.3 0.7 5.0 112.0 6.1 0.0 2.0 145.2 40.7 1.9 3.7 0.5 1.5 1.5 55.2 1.0 1.7 7.7 0.0 49.8 187.0 94.8 184.6 0.0 0.3 103.3 240.2 30.0 54.8 1.1 6.6 4.5 3.4 9.5 13.4 87.7 36.9 100.6 2.5 0.1 136.9 135.4 ERVFRD-1 "envFRD, ERVFRDE1, HERV-FRD, HERV-W/FRD, syncytin-2" ENSG00000244476 "Endogenous retrovirus group FRD member 1, envelope" P60508 6 11102489-11111725 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "placenta: 37.0" "Cell type enriched" "Detected in some" 56 "Syncytiotrophoblasts: 575.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SuSa: 38.8" HPA011812 Uncertain "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Actin filaments" "Nucleoplasm, Cytosol" "HPA011812: AB_1857702" "unprognostic (1.99e-1)" "unprognostic (3.29e-4)" "unprognostic (4.75e-2)" "unprognostic (1.80e-1)" "unprognostic (1.34e-1)" "unprognostic (2.19e-3)" "unprognostic (3.35e-1)" "unprognostic (6.44e-2)" "unprognostic (1.24e-1)" "unprognostic (1.99e-1)" "unprognostic (1.30e-2)" "unprognostic (2.78e-3)" "unprognostic (5.80e-4)" "unprognostic (3.40e-2)" "unprognostic (1.82e-1)" "unprognostic (1.95e-2)" "unprognostic (1.37e-2)" 0.3 0.4 0.6 0.1 0.4 0.2 0.4 1.8 0.6 0.4 0.0 0.3 0.5 0.3 1.0 0.3 0.2 0.4 0.1 0.6 0.7 0.5 0.2 0.6 0.0 0.6 0.4 0.0 0.0 7.5 0.0 37.0 0.5 0.3 0.2 0.2 0.2 0.2 0.0 0.5 0.5 0.2 0.1 0.0 0.3 0.1 0.6 0.4 0.0 0.4 0.0 0.5 0.2 0.6 0.0 0.1 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 38.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.4 1.8 0.6 0.6 0.7 0.6 0.4 0.5 0.1 0.6 0.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.6 0.0 0.6 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.1 0.3 0.0 0.0 10.1 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.1 0.0 0.0 0.0 575.5 0.4 0.5 0.0 0.0 EXD3 "FLJ20433, LOC54932, mut-7, Nbr" ENSG00000187609 "Exonuclease 3'-5' domain containing 3" Q8N9H8 9 137306896-137423211 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 73.2;Paneth cells: 178.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 29.4" "Low region specificity" "Detected in all" HPA047395 Approved Approved "Actin filaments,Focal adhesion sites" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 72: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Focal adhesion sites" "Actin filaments" "HPA047395: AB_10962864" "unprognostic (2.91e-1)" "unprognostic (5.67e-2)" "unprognostic (1.75e-3)" "prognostic favorable (4.30e-4)" "unprognostic (1.88e-1)" "unprognostic (1.70e-1)" "unprognostic (6.65e-2)" "unprognostic (1.37e-1)" "unprognostic (2.54e-2)" "unprognostic (1.10e-1)" "unprognostic (2.50e-3)" "unprognostic (1.72e-2)" "unprognostic (5.21e-2)" "unprognostic (7.99e-3)" "unprognostic (2.05e-1)" "unprognostic (8.67e-2)" "unprognostic (5.05e-2)" 9.4 10.1 6.2 3.5 6.8 3.5 10.8 5.9 11.0 11.5 6.6 16.0 9.4 9.9 1.5 11.6 12.3 4.2 11.2 6.5 5.8 12.2 8.1 10.2 3.8 7.2 6.1 10.7 9.8 3.7 13.5 3.4 6.4 14.5 3.6 0.8 10.1 3.7 9.5 10.2 11.3 1.4 5.5 14.8 12.3 4.8 6.1 1.1 11.4 2.6 2.3 10.9 11.2 6.3 8.3 7.0 3.3 9.5 2.8 4.0 7.8 4.0 4.5 3.5 5.3 4.8 17.5 3.5 9.1 3.1 8.7 14.5 1.0 4.4 1.1 8.2 8.1 2.6 13.0 7.9 8.5 1.9 29.4 4.8 6.0 3.1 2.8 10.2 11.9 0.0 7.0 6.4 3.0 22.3 0.1 6.9 3.8 18.1 4.7 6.3 2.6 25.3 7.1 4.7 4.5 7.7 4.0 8.4 3.8 3.8 13.6 9.3 15.0 4.8 4.4 7.5 6.2 8.1 4.1 3.0 8.7 6.4 7.4 10.7 3.4 7.8 2.2 4.5 2.7 2.6 4.0 2.1 3.9 2.4 3.1 2.5 0.8 4.1 4.4 2.5 6.1 2.3 6.2 6.8 5.9 11.0 6.5 5.8 7.2 6.1 6.4 5.5 6.1 6.3 17.6 0.0 6.3 24.2 5.3 5.9 10.0 8.9 13.6 14.6 13.5 17.0 5.2 10.0 11.2 7.3 14.6 9.9 8.1 46.4 9.8 6.8 17.9 11.5 6.5 14.1 7.3 5.0 21.6 11.3 3.3 7.3 19.4 13.1 61.7 10.5 17.2 7.2 9.2 21.9 24.1 27.6 16.2 5.4 7.3 73.2 5.9 6.9 3.6 13.1 6.2 10.0 12.3 26.2 14.6 6.4 178.2 7.9 6.6 10.0 31.3 11.9 9.3 10.4 13.1 5.5 9.9 2.3 8.9 9.9 8.9 4.0 6.4 19.5 39.0 9.2 FABP2 I-FABP ENSG00000145384 "Fatty acid binding protein 2" P12104 4 119317250-119322138 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 173 "intestine: 550.0" "Cell type enriched" "Detected in some" 10 "Proximal enterocytes: 5965.8" "Group enriched" "Detected in some" 9 "colorectal cancer: 3.2;pancreatic cancer: 1.6;stomach cancer: 2.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "basophil: 1.6;neutrophil: 4.2" "Lineage enriched" "Detected in single" 9 "granulocytes: 4.2" "Cell line enhanced" "Detected in some" "NB-4: 1.2;RPMI-8226: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA034607, CAB047325, CAB047326" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA 61000 "Cluster 1: Neutrophils - Mixed function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 45: Enterocytes - Digestion" "Actin filaments, Cytosol" "Plasma membrane" "CAB047325: , CAB047326: , HPA034607: AB_10601317" "unprognostic (3.94e-2)" "unprognostic (1.10e-1)" "unprognostic (1.05e-1)" "unprognostic (4.58e-1)" "unprognostic (1.51e-2)" "unprognostic (2.61e-2)" "unprognostic (1.69e-4)" "unprognostic (1.93e-1)" "unprognostic (1.02e-1)" 0.2 0.1 0.1 3.1 0.1 0.9 0.0 0.6 0.2 0.0 0.4 28.2 291.0 0.3 0.1 0.1 0.2 0.1 0.6 0.2 0.1 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 35.2 0.3 0.0 0.0 0.1 0.4 550.0 1.9 0.0 0.1 0.7 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 1.2 0.0 0.0 0.1 0.1 0.0 1.1 0.0 0.1 0.3 0.8 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.4 0.0 0.2 0.0 0.2 0.1 0.0 0.0 1.6 0.4 0.4 0.2 0.1 0.2 0.1 0.2 0.1 0.1 0.2 0.2 0.2 4.2 0.4 0.1 0.3 0.3 0.0 0.1 0.1 0.6 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.7 0.0 0.0 1.8 0.0 0.0 0.0 242.0 0.0 0.0 0.0 1.4 0.1 0.1 1.2 0.0 0.0 0.2 0.1 0.3 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 570.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 383.1 0.0 0.0 0.0 5965.8 17.3 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 222.5 0.0 FAM167B "C1orf90, DIORA-2, MGC10820" ENSG00000183615 "Family with sequence similarity 167 member B" Q9BTA0 1 32247222-32248856 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 44.0" "Group enriched" "Detected in many" 14 "Adipocytes: 68.5;Endothelial cells: 102.5;Hepatic stellate cells: 200.3" "Cancer enhanced" "Detected in all" "melanoma: 46.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.7" "Lineage enriched" "Detected in single" 5 "T-cells: 1.7" "Cell line enhanced" "Detected in many" "BJ hTERT+: 9.6;EFO-21: 12.0;SK-MEL-30: 30.9;U-2197: 29.9" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA029398, HPA062074" Uncertain Approved "Actin filaments" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Actin filaments" "HPA029398: AB_10602807, HPA062074: AB_2684677" "unprognostic (2.16e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (1.11e-4)" "unprognostic (6.03e-2)" "unprognostic (1.74e-2)" "unprognostic (3.36e-3)" "unprognostic (7.44e-3)" "unprognostic (3.64e-1)" "unprognostic (3.00e-3)" "unprognostic (1.02e-2)" "unprognostic (1.30e-2)" "unprognostic (8.89e-2)" "unprognostic (4.80e-2)" "unprognostic (2.69e-2)" "unprognostic (1.60e-1)" "unprognostic (8.04e-2)" "unprognostic (5.08e-2)" 19.9 19.7 4.3 4.1 3.8 0.2 10.0 3.8 6.3 14.3 4.3 7.4 2.8 12.9 0.5 4.0 10.3 4.2 11.0 3.8 4.5 44.0 10.7 20.5 2.7 4.5 4.1 4.1 8.4 4.3 14.4 4.2 4.5 16.5 2.1 1.4 4.7 5.9 3.0 2.4 8.1 5.8 4.4 1.9 7.5 0.9 5.1 0.8 19.9 1.1 1.5 13.2 7.7 4.3 0.9 1.8 0.6 0.0 1.2 1.1 0.0 4.3 9.6 1.9 2.7 0.1 0.9 0.2 12.0 7.3 2.2 1.4 0.3 0.0 0.6 0.1 0.0 0.0 4.6 0.5 0.4 0.0 0.1 1.0 0.7 1.4 0.4 2.6 3.5 0.6 0.0 0.1 0.2 0.6 0.2 0.0 0.3 0.2 4.1 0.9 0.0 1.2 1.2 0.4 1.8 0.4 2.8 0.2 30.9 0.8 0.5 0.1 3.2 0.8 0.9 29.9 0.1 0.1 0.3 0.7 0.3 0.2 0.4 0.0 0.0 0.2 0.8 0.0 0.2 0.1 0.2 0.2 0.0 0.3 0.1 0.5 0.0 0.1 0.0 0.0 1.7 0.2 4.3 3.8 3.8 6.3 3.8 4.5 4.5 4.1 4.5 4.4 5.1 4.3 68.5 0.0 1.1 0.3 3.2 0.3 0.5 0.2 0.0 0.4 2.8 2.8 0.4 0.0 0.1 5.5 0.0 0.1 2.7 1.3 0.0 0.5 0.0 1.3 3.5 102.5 0.0 8.0 0.0 0.8 0.2 3.7 1.5 1.0 0.0 0.2 200.3 1.7 0.6 0.0 0.1 1.3 0.0 8.5 2.2 0.0 2.8 1.4 1.8 2.8 0.0 0.0 2.1 0.5 0.4 0.2 1.2 1.2 0.6 0.6 0.0 0.1 1.3 0.5 0.0 0.6 1.6 0.0 0.3 0.3 1.0 0.3 2.1 0.9 0.7 0.3 FAM216A "C12orf24, HSU79274" ENSG00000204856 "Family with sequence similarity 216 member A" Q8WUB2 12 110468415-110490385 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 15.5;testis: 59.4" "Cell type enhanced" "Detected in many" "Late spermatids: 54.7;Spermatocytes: 215.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038286 Enhanced Approved "Actin filaments" NA NA "Cluster 30: Non-specific - Translation" "Cluster 78: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Actin filaments" "HPA038286: AB_2675931" "unprognostic (7.91e-2)" "unprognostic (3.73e-2)" "unprognostic (1.56e-1)" "unprognostic (6.02e-3)" "unprognostic (3.04e-1)" "unprognostic (2.76e-1)" "prognostic unfavorable (4.49e-5)" "unprognostic (8.49e-2)" "unprognostic (1.31e-1)" "unprognostic (1.70e-1)" "unprognostic (2.04e-3)" "unprognostic (3.25e-2)" "prognostic unfavorable (4.18e-10)" "unprognostic (7.60e-2)" "unprognostic (4.35e-2)" "unprognostic (6.66e-2)" "unprognostic (1.05e-1)" 3.4 7.5 9.4 6.6 9.6 4.1 3.8 12.9 15.5 4.8 4.7 3.6 1.1 5.8 2.0 3.2 4.5 4.3 9.1 9.7 12.7 3.0 3.2 2.1 7.4 10.4 9.4 7.0 2.0 5.5 5.2 3.6 10.3 3.9 2.2 8.8 1.7 4.4 3.3 1.4 3.2 6.0 8.9 3.9 2.3 59.4 11.1 7.3 3.2 4.3 4.5 4.8 3.2 9.7 31.1 25.8 21.6 28.5 13.7 25.9 3.5 57.3 14.4 63.9 28.3 27.5 8.5 101.2 13.1 24.2 18.1 19.9 38.1 33.3 77.9 30.0 72.8 49.9 17.6 23.4 22.8 68.3 39.1 25.1 7.8 32.5 71.6 47.8 20.5 39.5 63.1 26.7 48.4 11.2 50.4 106.4 64.6 13.6 41.9 24.4 29.6 68.9 24.7 0.9 77.4 27.5 24.4 18.4 14.2 7.8 43.6 49.2 18.9 22.4 7.5 19.9 58.8 41.7 38.9 79.7 31.7 61.0 37.7 0.9 3.6 1.0 1.9 3.1 3.7 7.3 3.7 3.6 4.5 8.2 9.3 5.6 2.9 2.8 2.6 2.4 2.4 3.9 9.4 9.6 12.9 15.5 9.7 12.7 10.4 9.4 10.3 8.9 11.1 9.7 2.4 0.0 1.5 7.8 9.6 1.7 6.0 8.7 7.4 11.6 3.0 7.5 20.1 0.0 3.6 3.7 2.1 0.7 1.4 0.1 0.0 4.1 38.6 3.2 17.5 4.4 1.2 17.2 20.4 0.9 3.0 10.8 1.1 0.7 10.2 6.6 3.9 3.4 8.1 13.5 21.6 0.1 2.0 4.4 2.1 54.7 9.6 3.7 3.6 5.6 4.2 4.2 6.2 14.1 8.9 2.8 0.0 5.7 3.9 8.0 0.1 4.4 5.1 5.1 13.1 8.4 9.3 215.9 21.6 5.1 2.0 0.5 3.6 12.2 0.4 1.5 FCHSD2 "KIAA0769, SH3MD3" ENSG00000137478 "FCH and double SH3 domains 2" O94868 11 72836745-73142318 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 219.6;Microglial cells: 387.8;Oligodendrocyte precursor cells: 471.0;Oligodendrocytes: 198.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 164.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038545, HPA038546" Uncertain Approved "Nuclear speckles,Plasma membrane,Actin filaments,Focal adhesion sites" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Actin filaments" "Nuclear speckles, Focal adhesion sites" "HPA038545: AB_2676074, HPA038546: AB_10673013" "unprognostic (1.80e-2)" "unprognostic (1.50e-2)" "prognostic favorable (1.71e-4)" "unprognostic (1.63e-1)" "unprognostic (3.14e-2)" "unprognostic (2.62e-3)" "unprognostic (1.41e-2)" "unprognostic (2.62e-1)" "unprognostic (1.27e-2)" "unprognostic (2.56e-1)" "unprognostic (3.69e-2)" "unprognostic (6.16e-2)" "unprognostic (2.89e-3)" "unprognostic (2.02e-1)" "unprognostic (4.70e-1)" "unprognostic (2.92e-1)" "unprognostic (1.23e-1)" 22.2 19.2 43.3 33.4 47.9 28.6 16.8 31.5 38.7 14.9 34.6 14.5 8.9 16.0 6.9 11.7 13.8 22.6 25.5 37.0 44.5 13.0 17.6 23.9 45.2 36.6 36.4 32.3 10.4 9.9 8.1 31.2 35.4 11.6 14.4 19.6 9.3 13.8 8.8 9.0 17.7 17.2 32.5 42.3 13.1 22.6 41.3 28.5 14.9 14.7 46.1 21.6 11.7 45.0 14.2 12.3 26.0 31.3 9.8 23.9 21.8 26.7 50.6 14.8 12.0 9.6 21.0 76.3 31.3 31.0 15.6 20.0 15.3 14.1 21.0 27.2 7.0 64.2 14.3 33.4 25.7 30.6 7.6 14.6 15.6 15.1 17.7 33.4 35.7 26.7 13.7 49.6 19.5 16.1 36.4 54.7 5.5 15.6 13.8 56.4 39.8 164.1 24.8 21.4 13.1 16.9 9.6 16.2 31.9 12.2 12.4 23.7 47.9 45.9 18.5 32.9 7.5 46.8 29.4 71.2 8.4 51.4 13.8 18.3 8.4 18.7 2.8 5.1 1.9 22.2 2.8 3.2 8.1 26.9 3.2 4.1 19.9 2.0 3.0 32.3 3.2 3.6 43.3 47.9 31.5 38.7 37.0 44.5 36.6 36.4 35.4 32.5 41.3 45.0 47.3 9.6 14.0 114.9 76.7 8.5 5.2 3.6 9.1 13.5 5.9 4.7 16.0 8.6 6.1 3.7 25.0 12.4 39.4 1.9 1.9 4.1 6.2 6.6 8.3 30.2 4.8 19.4 79.4 6.2 9.2 9.4 7.7 5.4 2.5 33.6 46.1 11.3 19.9 10.1 219.6 7.7 4.1 30.8 29.9 10.0 10.8 32.8 5.4 387.8 20.6 10.6 5.2 471.0 198.1 5.3 5.7 16.6 70.1 3.8 1.8 3.5 3.9 17.0 6.6 13.0 26.1 9.6 13.0 7.1 5.8 12.0 14.9 6.0 3.7 4.8 FGD4 "CMT4H, frabin, FRABP, ZFYVE6" ENSG00000139132 "FYVE, RhoGEF and PH domain containing 4" Q96M96 12 32399558-32646050 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Guanine-nucleotide releasing factor" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 232.5;Early spermatids: 196.3;Late spermatids: 250.1;Microglial cells: 203.3" "Cancer enhanced" "Detected in all" "testis cancer: 14.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 3.6;granulocytes: 8.4;monocytes: 5.7" "Cell line enhanced" "Detected in many" "ASC diff: 24.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039235 Approved Approved "Actin filaments" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 41: Macrophages - Immune response" "Actin filaments" "HPA039235: AB_10673420" "unprognostic (6.73e-2)" "unprognostic (2.55e-2)" "unprognostic (5.99e-2)" "unprognostic (2.64e-2)" "unprognostic (2.37e-1)" "unprognostic (5.45e-2)" "unprognostic (8.61e-3)" "unprognostic (3.91e-2)" "unprognostic (5.48e-2)" "unprognostic (2.19e-1)" "unprognostic (1.13e-3)" "unprognostic (2.79e-1)" "prognostic favorable (7.16e-5)" "unprognostic (9.50e-2)" "unprognostic (7.52e-2)" "unprognostic (1.17e-1)" "unprognostic (3.41e-3)" 12.6 4.3 8.1 5.6 10.3 12.1 8.0 11.4 6.7 6.1 13.8 9.4 8.8 2.3 2.9 7.4 4.9 10.3 5.3 7.4 10.3 10.8 17.7 8.1 1.8 12.3 10.1 24.6 9.4 14.8 3.1 10.4 12.4 4.6 10.1 23.6 6.7 4.0 10.8 7.4 8.2 3.4 9.2 5.2 28.9 12.1 9.5 1.7 6.3 10.8 2.7 4.0 5.9 13.7 5.4 2.6 6.6 2.0 24.1 14.8 8.1 4.5 22.5 1.2 0.4 8.1 8.3 0.8 2.5 0.3 2.8 5.1 5.3 7.5 0.7 0.7 2.6 4.7 2.7 2.5 4.3 0.9 0.0 8.8 10.3 6.0 12.9 3.3 11.6 1.1 0.5 5.4 15.6 1.9 0.0 1.7 17.4 5.3 0.2 0.4 6.9 16.2 8.0 5.3 7.2 8.5 4.7 4.4 6.6 11.8 7.0 0.3 13.1 0.1 1.5 18.8 0.7 1.9 4.6 2.9 0.0 2.8 5.2 3.6 3.8 8.4 0.2 5.7 0.2 0.6 0.3 0.2 3.6 1.4 0.2 0.3 5.5 0.7 5.1 0.4 0.2 1.3 8.1 10.3 11.4 6.7 7.4 10.3 12.3 10.1 12.4 9.2 9.5 13.7 84.3 48.1 31.4 232.5 5.6 8.4 11.3 12.1 8.6 23.8 10.7 7.5 19.2 54.3 18.3 22.0 118.9 1.3 0.5 57.8 13.7 16.8 196.3 36.0 8.1 24.8 19.2 4.4 40.5 20.7 16.8 19.9 78.5 65.7 2.5 34.1 9.3 37.7 11.8 70.7 55.1 31.2 26.4 71.7 22.3 250.1 4.7 92.9 14.2 203.3 39.9 79.3 1.0 25.1 95.1 33.5 29.3 1.5 16.4 16.4 54.8 15.0 15.3 114.5 52.6 16.5 41.3 10.4 7.4 25.0 12.6 1.4 3.1 25.6 30.5 20.2 FHL2 "DRAL, SLIM3" ENSG00000115641 "Four and a half LIM domains 2" Q14192 2 105357712-105438513 "Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "heart muscle: 1421.4;ovary: 535.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 1077.5;Extravillous trophoblasts: 585.9;Granulosa cells: 851.4;Leydig cells: 567.0;Peritubular cells: 1049.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 5.7" "Group enriched" "Detected in many" 6 "granulocytes: 5.7;T-cells: 2.7" "Cell line enhanced" "Detected in many" "LHCN-M2: 534.6;RPTEC TERT1: 489.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005922, HPA006028, CAB008368" Enhanced Enhanced "Actin filaments,Focal adhesion sites" NA Yes 14000 "Cluster 18: Basophils - Vesicular transport" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments, Focal adhesion sites" "CAB008368: AB_591383, HPA005922: AB_1078860, HPA006028: AB_1078858" "unprognostic (1.04e-1)" "unprognostic (1.63e-3)" "unprognostic (3.30e-1)" "unprognostic (3.42e-2)" "unprognostic (5.89e-2)" "prognostic unfavorable (2.01e-4)" "unprognostic (2.80e-2)" "unprognostic (1.02e-3)" "unprognostic (1.81e-1)" "unprognostic (2.42e-2)" "unprognostic (3.34e-2)" "unprognostic (8.11e-2)" "prognostic unfavorable (6.42e-5)" "unprognostic (2.06e-1)" "unprognostic (3.49e-1)" "unprognostic (9.92e-3)" "unprognostic (4.73e-2)" 68.3 70.2 10.4 28.9 13.2 17.0 65.4 7.6 18.2 101.9 15.0 75.2 48.5 105.1 33.8 55.4 55.8 81.5 1421.4 18.9 7.4 55.2 22.1 17.5 17.2 6.7 7.2 535.4 9.1 8.2 29.3 79.3 7.0 88.8 56.8 8.5 45.3 63.8 67.5 44.2 50.4 91.5 7.5 20.1 94.9 50.9 7.9 22.8 41.3 118.6 13.9 105.5 47.2 12.2 156.8 36.1 20.9 0.8 65.2 81.7 196.4 289.3 75.9 182.2 216.7 65.6 237.6 0.4 23.7 353.6 223.8 47.7 31.4 262.4 204.2 6.5 23.9 108.7 42.9 49.0 257.6 0.4 23.5 171.7 142.2 286.0 188.1 360.8 374.4 18.0 29.0 8.9 534.6 5.6 25.8 1.0 44.1 108.3 113.2 0.4 31.6 4.3 489.8 108.4 1.0 6.9 109.2 48.1 76.9 20.5 60.7 3.9 183.1 130.4 134.1 146.4 236.0 3.3 0.6 0.7 208.1 0.6 138.5 5.7 0.4 0.4 1.1 0.2 0.7 0.6 0.9 2.0 0.4 0.5 0.7 1.5 2.2 0.7 0.2 0.6 2.7 1.5 10.4 13.2 7.6 18.2 18.9 7.4 6.7 7.2 7.0 7.5 7.9 12.2 15.7 9.6 5.1 0.7 1.0 468.5 1077.5 342.5 389.9 9.5 59.8 126.2 362.1 15.7 91.0 29.5 2.1 220.4 1.7 212.6 3.9 100.7 5.7 44.8 40.4 27.4 58.2 63.5 46.3 117.9 585.9 96.1 186.1 32.5 10.2 851.4 17.2 9.2 25.3 0.0 4.9 169.8 73.2 0.6 31.8 17.3 567.0 10.4 23.2 25.3 2.7 1.6 0.0 0.5 1.6 234.5 258.2 1049.0 6.7 198.2 51.7 28.1 19.1 13.0 216.9 60.6 171.0 9.1 17.7 124.5 296.9 178.7 7.7 193.5 55.8 536.2 FILIP1 "FILIP, KIAA1275" ENSG00000118407 "Filamin A interacting protein 1" Q7Z7B0 6 75291859-75493800 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 53.8;skeletal muscle: 35.8;tongue: 48.9" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 582.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.9;HUVEC TERT2: 1.7;RPTEC TERT1: 1.9;U-266/70: 6.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA053564 Enhanced Approved "Plasma membrane,Actin filaments" No NA "Cluster 38: Heart - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Actin filaments" "HPA053564: AB_2682192" "unprognostic (4.90e-2)" "unprognostic (3.77e-2)" "unprognostic (9.77e-3)" "unprognostic (3.83e-1)" "unprognostic (1.52e-1)" "unprognostic (4.98e-1)" "unprognostic (2.27e-2)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (5.17e-3)" "unprognostic (3.29e-2)" "unprognostic (2.23e-1)" "unprognostic (1.30e-3)" "unprognostic (3.97e-3)" "unprognostic (2.34e-1)" "unprognostic (4.65e-2)" "unprognostic (7.66e-3)" 6.8 1.5 1.5 2.9 1.8 0.2 2.4 0.1 2.5 1.8 0.7 11.7 1.8 8.5 0.9 9.5 4.8 5.7 53.8 4.1 0.5 1.8 3.2 7.6 1.2 0.2 0.5 1.3 1.4 12.4 1.4 5.1 0.3 3.9 3.3 0.4 1.2 3.4 35.8 0.6 2.6 13.2 0.5 0.3 3.2 2.1 0.8 1.1 2.3 48.9 0.9 10.9 1.6 1.5 0.0 1.3 0.2 0.1 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 6.9 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.2 0.0 0.0 0.1 0.1 0.9 0.0 0.1 0.0 0.0 1.7 0.2 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.4 0.1 0.1 0.0 0.1 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.9 0.7 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 1.5 1.8 0.1 2.5 4.1 0.5 0.2 0.5 0.3 0.5 0.8 1.5 82.1 128.2 82.6 5.9 0.5 0.6 0.5 2.8 0.0 3.5 0.5 0.8 582.5 0.0 9.1 0.0 0.0 0.8 0.5 0.1 1.9 0.1 54.2 18.2 1.7 45.9 0.0 2.7 9.7 0.4 0.3 60.3 0.0 19.2 1.3 1.7 72.1 0.7 1.3 0.0 12.8 0.1 8.2 1.9 1.2 17.6 2.5 1.8 1.8 5.6 0.0 2.5 1.0 6.0 10.0 0.0 0.0 4.5 0.0 0.8 0.4 0.1 62.4 3.5 92.1 70.2 114.2 7.1 7.9 0.7 0.9 0.8 1.8 11.9 0.1 0.4 FLNA "ABP-280, FLN, FLN1, OPD1, OPD2" ENSG00000196924 "Filamin A" P21333 X 154348524-154374634 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation" Actin-binding "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 1203.7;intestine: 1462.2" "Cell type enhanced" "Detected in many" "Peritubular cells: 500.6;Sertoli cells: 420.7;Smooth muscle cells: 459.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000356, HPA000368, HPA001016, HPA001115, HPA002925" Enhanced Approved Enhanced "Plasma membrane,Actin filaments,Cytosol" NA NA 730000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Actin filaments, Cytosol" "CAB000356: , HPA000368: AB_2797215, HPA001016: , HPA001115: AB_1078871, HPA002925: AB_1078869" "unprognostic (1.39e-1)" "unprognostic (9.40e-3)" "prognostic unfavorable (7.37e-4)" "unprognostic (3.68e-2)" "unprognostic (2.55e-1)" "unprognostic (6.05e-3)" "unprognostic (5.08e-2)" "unprognostic (1.08e-1)" "unprognostic (6.02e-2)" "unprognostic (1.30e-1)" "unprognostic (3.23e-2)" "unprognostic (9.58e-2)" "prognostic unfavorable (1.54e-6)" "unprognostic (5.49e-3)" "unprognostic (1.78e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (3.88e-4)" 267.4 55.9 14.4 223.2 18.5 157.9 164.2 15.2 43.0 392.1 54.7 1462.2 89.9 1203.7 35.5 454.7 609.4 137.9 108.4 14.8 23.0 70.5 21.2 238.9 65.0 39.9 19.9 236.7 50.5 13.4 30.5 79.2 24.4 369.2 86.9 9.0 80.3 617.2 49.7 124.7 354.6 706.6 21.1 102.7 508.0 33.7 34.0 48.1 85.6 31.2 38.1 1053.9 286.4 21.5 947.2 719.2 246.7 316.1 209.8 278.4 400.9 614.0 680.1 552.5 489.8 469.2 169.4 80.5 1551.4 966.4 970.1 528.3 224.0 538.1 152.7 333.6 77.8 262.2 914.9 159.7 375.9 309.3 324.9 266.1 126.1 825.5 327.0 533.8 417.1 94.9 74.7 538.7 401.3 210.7 148.5 93.1 258.3 97.9 470.9 147.8 221.2 71.6 197.2 193.4 52.9 119.7 515.8 80.2 381.1 187.3 79.1 96.3 1016.6 625.2 586.8 640.0 1147.1 333.7 212.8 162.3 580.3 202.4 638.7 7.6 24.9 11.8 32.6 23.1 21.2 10.2 15.6 29.2 22.4 4.6 6.0 14.3 3.6 10.5 34.2 2.7 20.7 56.2 14.4 18.5 15.2 43.0 14.8 23.0 39.9 19.9 24.4 21.1 34.0 21.5 105.1 57.7 38.7 30.0 76.9 124.3 85.9 127.8 85.4 3.5 40.9 153.5 34.5 38.6 26.1 35.0 0.0 24.6 257.7 2.6 1.9 272.0 2.1 33.8 186.3 107.0 1.8 39.7 11.8 133.1 90.9 137.9 13.3 55.8 26.0 334.5 81.8 4.3 120.3 11.8 8.6 2.5 22.4 141.0 263.0 13.7 122.4 227.7 88.9 30.9 207.9 39.4 270.8 8.0 2.6 347.4 1.5 500.6 98.7 96.1 1.9 3.0 9.1 4.3 420.7 118.3 459.3 4.1 8.9 48.8 73.6 20.0 172.3 134.7 3.3 35.3 FLNB "ABP-278, FH1, FLN1L, LRS1, TABP, TAP" ENSG00000136068 "Filamin B" O75369 3 58008400-58172251 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Differentiation, Myogenesis" "Actin-binding, Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 344.9;Pancreatic endocrine cells: 385.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 17.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 523.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004747, HPA004886, CAB019322" Enhanced Supported "Golgi apparatus,Plasma membrane,Actin filaments,Cytosol" NA NA 20000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 1: Thyroid gland - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus, Actin filaments, Cytosol" "CAB019322: , HPA004747: AB_1848599, HPA004886: AB_1848600" "unprognostic (1.29e-2)" "unprognostic (1.08e-2)" "unprognostic (5.97e-2)" "unprognostic (6.86e-2)" "unprognostic (1.26e-1)" "unprognostic (2.05e-1)" "unprognostic (6.52e-2)" "unprognostic (1.72e-1)" "unprognostic (9.61e-2)" "unprognostic (5.02e-3)" "prognostic unfavorable (8.45e-5)" "unprognostic (9.23e-2)" "prognostic favorable (3.45e-6)" "unprognostic (4.38e-2)" "unprognostic (1.36e-1)" "unprognostic (6.65e-3)" "unprognostic (2.33e-1)" 74.6 63.1 42.8 22.3 51.3 7.4 90.4 50.9 52.4 45.5 57.1 122.2 52.8 75.5 120.3 57.7 75.9 19.6 47.2 40.1 41.6 96.7 71.5 49.9 24.4 54.4 52.3 68.9 83.2 59.9 38.1 48.0 52.6 124.4 74.4 10.2 64.0 51.4 16.3 91.3 92.7 36.2 48.1 55.3 70.2 30.4 50.0 74.8 91.1 17.8 23.8 114.7 58.6 58.3 134.4 225.0 22.3 32.9 14.8 25.0 385.7 49.0 39.3 106.6 108.4 227.1 223.1 21.9 18.1 172.9 172.8 215.9 42.1 311.5 103.0 121.6 20.8 18.4 192.7 110.5 107.8 16.2 63.1 40.2 132.1 148.5 448.3 125.2 365.4 94.7 30.9 6.6 67.0 29.2 49.3 38.5 34.5 146.6 192.1 21.6 5.8 18.7 143.8 224.6 24.7 23.1 247.3 132.6 27.4 160.9 110.3 44.6 523.3 27.8 84.5 334.1 175.6 4.8 1.7 17.0 102.2 29.2 29.9 10.1 0.3 5.0 0.5 0.8 2.7 4.1 1.7 0.8 1.4 1.6 5.1 3.8 0.2 7.3 1.5 17.9 2.0 1.5 42.8 51.3 50.9 52.4 40.1 41.6 54.4 52.3 52.6 48.1 50.0 58.3 133.7 51.3 30.2 3.9 11.0 50.6 42.9 73.2 29.0 3.3 86.6 43.4 10.0 57.2 62.0 47.8 39.6 28.7 36.8 344.9 0.0 93.8 15.6 103.6 24.4 92.9 49.2 10.3 34.1 67.1 207.1 28.8 88.7 133.8 24.7 34.4 151.3 52.0 14.6 1.7 34.3 82.8 38.7 11.3 12.2 22.4 16.1 11.1 5.4 22.5 11.6 9.1 2.1 25.1 40.9 385.7 161.0 27.8 3.4 115.2 157.3 6.5 76.1 10.6 0.0 4.4 25.9 4.4 6.9 46.4 51.7 49.8 9.9 84.6 93.0 88.4 FLT1 "FLT, VEGFR1" ENSG00000102755 "Fms related receptor tyrosine kinase 1" P17948 13 28300346-28495145 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "placenta: 432.4" "Cell type enhanced" "Detected in many" "Adipocytes: 411.6;Endothelial cells: 263.1;Extravillous trophoblasts: 815.4;Hepatic stellate cells: 234.9;Microglial cells: 433.8;Syncytiotrophoblasts: 1127.1" "Cancer enhanced" "Detected in all" "renal cancer: 28.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 71.8;BJ hTERT+: 57.2;HMC-1: 349.2;HUVEC TERT2: 64.9;WM-115: 127.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011740, HPA014290, CAB068189, CAB068190" Enhanced Supported "Plasma membrane,Actin filaments" "Secreted to blood" NA NA 876000 87000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "Actin filaments" "CAB068189: AB_2665636, CAB068190: AB_2665637, HPA011740: AB_1858737, HPA014290: AB_1858738" "unprognostic (3.33e-2)" "unprognostic (3.52e-3)" "unprognostic (1.13e-3)" "unprognostic (5.02e-2)" "unprognostic (3.65e-1)" "unprognostic (5.03e-2)" "unprognostic (8.25e-2)" "unprognostic (2.27e-3)" "unprognostic (9.91e-2)" "unprognostic (6.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.19e-4)" "unprognostic (4.20e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (6.32e-2)" 47.6 9.6 37.6 9.1 36.2 1.1 31.2 37.0 43.0 16.4 24.6 9.4 7.5 17.2 3.7 5.9 11.7 16.6 46.0 33.3 39.8 34.9 18.2 25.8 5.3 44.6 40.0 4.4 12.7 30.5 9.0 432.4 50.1 13.9 6.1 52.5 7.0 11.0 19.9 5.9 9.3 17.4 33.4 18.6 10.9 17.4 59.6 3.6 48.9 38.8 5.7 14.0 9.5 38.7 0.1 0.0 0.0 0.6 0.6 0.9 0.3 71.8 57.2 25.8 14.9 0.0 0.2 0.1 0.1 9.6 0.0 0.3 6.7 0.0 45.4 0.0 2.0 0.2 0.1 0.0 0.1 0.0 349.2 0.6 0.0 0.1 1.0 0.1 64.9 6.1 1.7 0.3 0.0 0.3 4.5 3.7 37.5 0.0 0.1 2.9 0.0 0.1 0.1 0.1 8.1 0.6 0.0 0.1 0.2 44.4 0.3 0.2 6.3 0.2 1.2 0.1 0.1 2.1 1.0 0.2 0.4 0.3 127.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 37.6 36.2 37.0 43.0 33.3 39.8 44.6 40.0 50.1 33.4 59.6 38.7 411.6 0.0 6.0 2.0 4.7 4.1 0.7 0.2 3.4 17.8 1.2 1.5 26.5 2.8 2.9 0.0 4.2 197.2 1.4 0.1 1.9 0.6 157.2 0.5 1.5 263.1 0.0 0.0 0.9 0.0 815.4 32.1 0.5 2.1 1.3 0.1 234.9 6.9 30.8 1.7 14.5 0.0 0.0 12.5 23.6 173.8 18.6 15.3 0.0 433.8 0.0 153.2 0.0 9.5 2.0 0.0 0.0 48.5 4.1 1.3 0.0 0.1 1.8 9.7 92.1 11.4 30.1 14.6 4.6 1.0 4.8 1127.1 2.8 1.5 0.0 1.1 FMN2 ENSG00000155816 "Formin 2" Q9NZ56 1 240014348-240475187 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, Protein transport, Stress response, Transport" "Actin-binding, Developmental protein" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 46.0;parathyroid gland: 19.7;retina: 16.7" "Cell type enhanced" "Detected in many" "Astrocytes: 758.1;Excitatory neurons: 537.5;Horizontal cells: 124.5;Inhibitory neurons: 366.7;Oligodendrocyte precursor cells: 154.3" "Group enriched" "Detected in some" 8 "glioma: 5.9;testis cancer: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 70.8;BJ hTERT+: 39.4;fHDF/TERT166: 73.8;LHCN-M2: 87.9;U-138 MG: 48.9;WM-115: 69.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050649 Approved "Plasma membrane,Actin filaments" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Actin filaments" "HPA050649: AB_2681202" "unprognostic (1.55e-2)" "unprognostic (8.21e-2)" "unprognostic (4.01e-2)" "unprognostic (8.06e-2)" "unprognostic (2.77e-1)" "unprognostic (1.76e-1)" "unprognostic (7.97e-3)" "unprognostic (2.11e-2)" "unprognostic (2.93e-1)" "unprognostic (3.92e-2)" "unprognostic (3.35e-3)" "unprognostic (4.08e-1)" "unprognostic (1.11e-2)" "unprognostic (8.03e-3)" "unprognostic (9.78e-2)" "unprognostic (3.10e-2)" "unprognostic (1.40e-3)" 1.2 5.1 27.6 0.2 29.6 0.0 0.5 11.8 46.0 0.4 0.0 6.8 0.2 1.4 0.9 0.7 1.9 1.2 0.1 28.4 20.9 3.6 0.0 0.3 0.0 21.2 29.7 2.4 1.0 19.7 9.0 0.2 14.4 1.6 1.6 16.7 0.3 2.6 0.1 0.2 0.9 1.7 16.0 0.2 0.7 2.2 39.0 0.0 0.5 0.2 0.1 0.3 0.3 30.9 0.0 2.1 6.6 0.0 20.2 15.3 0.0 70.8 39.4 31.0 16.3 0.0 0.0 0.0 0.0 73.8 1.2 0.0 1.3 0.0 28.8 0.0 5.8 0.0 0.7 0.0 0.1 0.0 0.0 1.7 0.0 8.5 1.9 17.0 0.0 0.0 0.0 0.0 87.9 0.0 0.0 0.1 2.3 0.0 2.2 0.0 0.2 0.0 0.0 0.0 12.0 10.6 0.0 0.1 0.3 0.2 2.1 0.1 0.3 48.9 0.2 16.0 18.2 0.0 0.0 0.0 10.4 0.0 69.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.6 29.6 11.8 46.0 28.4 20.9 21.2 29.7 14.4 16.0 39.0 30.9 0.0 0.0 0.0 758.1 0.0 0.1 0.0 0.0 0.0 30.6 0.2 0.3 1.6 0.0 0.0 1.8 50.1 0.1 0.0 4.7 0.0 0.0 15.2 4.3 0.7 0.5 12.1 0.0 537.5 0.0 0.1 1.4 0.0 1.1 0.0 0.8 2.9 0.1 0.1 124.5 366.7 0.5 0.0 0.6 0.6 3.0 0.3 0.1 1.8 31.9 0.0 2.3 0.0 154.3 17.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.3 1.8 4.4 0.0 0.0 0.5 0.0 3.1 1.6 0.0 FNDC7 FLJ35838 ENSG00000143107 "Fibronectin type III domain containing 7" Q5VTL7 1 108712908-108742749 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.3;testis: 1.1" "Cell type enhanced" "Detected in some" "Astrocytes: 2.6;Early spermatids: 4.6;Late spermatids: 1.5;Oligodendrocyte precursor cells: 3.5;Oligodendrocytes: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA028079, HPA054297" Enhanced Approved "Nucleoplasm,Actin filaments" "Secreted in male reproductive system" NA NA "Cluster 77: Retina - Visual perception" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Actin filaments" Nucleoplasm "HPA028079: AB_10602501, HPA054297: AB_2682441" "unprognostic (2.35e-2)" "unprognostic (2.65e-2)" "unprognostic (3.74e-1)" "unprognostic (8.10e-2)" "unprognostic (1.30e-1)" "unprognostic (1.64e-1)" "unprognostic (1.13e-4)" "unprognostic (1.90e-10)" "unprognostic (1.59e-2)" "unprognostic (1.33e-1)" "unprognostic (1.31e-1)" 0.0 0.0 0.4 0.0 0.4 0.1 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 1.1 1.3 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.4 0.4 0.8 0.4 1.1 1.3 0.6 0.7 0.4 0.5 0.2 0.0 0.0 2.6 0.2 0.0 0.0 0.0 0.0 1.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 4.6 0.1 0.3 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.1 0.8 0.0 3.5 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.7 0.1 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.1 FRMD1 "bA164L23.1, DKFZp434O0117, FLJ00181, FLJ22615, FLJ40260" ENSG00000153303 "FERM domain containing 1" Q8N878 6 168053166-168101511 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 6.8;lymphoid tissue: 13.1;stomach 1: 5.7;testis: 5.1" "Group enriched" "Detected in some" 4 "Distal enterocytes: 68.9;Paneth cells: 167.2" "Cancer enriched" "Detected in single" 6 "colorectal cancer: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "K-562: 1.9;RPMI-8226: 3.0" "Low region specificity" "Detected in many" HPA030347 Enhanced Approved "Actin filaments" NA NA "Cluster 3: T-cells - Adaptive immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Actin filaments" "HPA030347: AB_10600207" "unprognostic (2.43e-2)" "unprognostic (2.74e-1)" "unprognostic (2.50e-1)" "unprognostic (1.28e-1)" "unprognostic (1.25e-1)" "unprognostic (2.58e-4)" "unprognostic (8.63e-2)" "unprognostic (2.62e-1)" "unprognostic (7.51e-2)" "unprognostic (9.12e-2)" "unprognostic (8.23e-2)" "unprognostic (1.71e-2)" "unprognostic (1.01e-1)" "unprognostic (9.11e-3)" 3.6 0.0 0.0 0.4 0.0 0.0 1.4 0.0 0.0 0.0 0.0 6.8 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.6 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.1 0.0 0.2 0.0 3.1 0.1 0.0 2.1 5.7 5.1 0.0 13.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 1.8 0.0 0.0 0.0 68.9 0.0 0.0 15.3 0.0 0.0 0.2 7.8 0.0 0.0 1.8 0.0 0.4 4.6 0.1 0.0 0.3 0.4 0.6 0.0 0.0 0.0 16.0 0.0 0.0 0.0 20.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 167.2 1.5 0.0 0.0 19.6 23.8 0.0 0.0 0.0 0.3 0.7 13.4 8.2 0.0 0.0 0.1 0.1 15.2 12.6 0.2 GAS7 "KIAA0394, MGC1348" ENSG00000007237 "Growth arrest specific 7" O60861 17 9910606-10198606 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 133.6;Fibroblasts: 79.6;Inhibitory neurons: 76.6;Late spermatids: 73.4;Oligodendrocytes: 163.3" "Group enriched" "Detected in all" 4 "glioma: 15.7;melanoma: 54.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 26.2" "Group enriched" "Detected in many" 4 "granulocytes: 17.1;monocytes: 26.2" "Cell line enriched" "Detected in many" 9 "WM-115: 533.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004838, HPA064678" Enhanced Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 6: Brain - Smell perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Actin filaments, Focal adhesion sites" "HPA004838: AB_2667263, HPA064678: AB_2685319" "unprognostic (1.68e-2)" "unprognostic (2.84e-3)" "unprognostic (1.80e-1)" "unprognostic (1.28e-3)" "unprognostic (1.15e-1)" "unprognostic (1.01e-2)" "unprognostic (7.32e-2)" "unprognostic (7.16e-2)" "unprognostic (2.88e-1)" "unprognostic (1.50e-2)" "unprognostic (2.48e-1)" "unprognostic (1.79e-1)" "unprognostic (1.94e-3)" "unprognostic (6.48e-2)" "unprognostic (8.78e-2)" "unprognostic (3.08e-2)" "prognostic unfavorable (6.89e-4)" 27.3 8.5 34.9 23.7 68.9 31.1 15.3 75.4 79.8 29.9 0.0 26.3 7.3 13.3 4.3 23.8 17.8 16.3 46.1 61.9 8.4 1.7 2.3 17.1 9.1 23.4 24.1 7.8 3.4 1.1 2.6 16.2 15.8 8.5 12.0 30.1 7.8 10.8 5.8 33.7 11.9 24.0 14.3 16.1 8.9 17.4 32.9 9.3 4.6 6.8 10.3 18.3 19.5 85.3 0.1 0.5 0.6 1.0 16.5 22.5 0.3 0.8 0.0 2.6 1.1 0.1 0.2 6.6 1.9 6.6 0.3 0.3 0.0 0.0 1.6 0.0 1.5 0.0 1.3 0.7 5.3 1.8 48.7 4.3 0.3 5.1 0.1 0.0 0.0 42.7 0.0 0.6 0.0 0.0 54.3 15.4 2.6 2.1 0.0 14.3 0.1 49.6 0.0 0.2 0.1 3.0 0.2 0.2 60.1 21.0 2.8 24.7 0.0 0.2 3.4 0.1 0.1 0.4 0.0 0.0 0.4 35.1 533.8 0.6 26.2 17.1 2.8 6.9 0.9 0.5 0.3 1.4 5.3 0.6 0.2 1.4 16.4 4.5 4.9 1.0 0.0 7.7 34.9 68.9 75.4 79.8 61.9 8.4 23.4 24.1 15.8 14.3 32.9 85.3 2.9 0.0 4.2 6.8 3.3 8.3 4.5 1.5 1.2 34.6 1.6 2.3 13.3 0.0 1.1 5.5 27.1 1.0 14.5 0.0 0.0 1.0 62.3 17.7 12.8 5.7 0.0 0.4 133.6 0.0 1.8 79.6 0.0 26.3 17.2 7.9 5.0 0.9 39.2 0.0 76.6 0.0 0.0 66.7 32.2 73.4 10.2 54.3 33.8 52.5 57.2 9.5 18.6 11.1 163.3 0.2 0.0 1.9 5.5 2.0 0.0 0.1 16.3 31.7 0.0 67.0 7.1 1.6 6.7 1.0 16.6 1.9 7.4 0.2 0.0 4.9 GFRAL "bA360D14.1, C6orf144, GRAL, UNQ9356" ENSG00000187871 "GDNF family receptor alpha like" Q6UXV0 6 55327469-55402493 "Predicted membrane proteins" Receptor "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047372 Uncertain Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "Actin filaments, Focal adhesion sites" "HPA047372: AB_2680017" "unprognostic (2.31e-1)" 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.3 0.3 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GPR137 "C11orf4, GPR137A, TM7SF1L1" ENSG00000173264 "G protein-coupled receptor 137" Q96N19 11 64270062-64289500 "Predicted intracellular proteins, Predicted membrane proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 203.8" "Cell type enhanced" "Detected in all" "Early spermatids: 193.1;Late spermatids: 573.0;Spermatocytes: 175.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 14.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062871 Uncertain Approved "Nucleoplasm,Nucleoli,Actin filaments" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Nucleoli" "Actin filaments" "HPA062871: AB_2684889" "unprognostic (2.25e-1)" "unprognostic (4.21e-2)" "unprognostic (6.81e-2)" "unprognostic (1.06e-1)" "unprognostic (1.29e-3)" "unprognostic (6.37e-2)" "prognostic unfavorable (5.34e-4)" "unprognostic (5.68e-2)" "unprognostic (1.83e-2)" "unprognostic (7.61e-3)" "prognostic favorable (6.18e-4)" "unprognostic (4.95e-2)" "unprognostic (8.66e-3)" "unprognostic (3.67e-3)" "unprognostic (2.28e-1)" "unprognostic (2.13e-1)" "unprognostic (5.41e-1)" 20.6 32.6 54.4 16.4 50.9 13.7 19.6 49.4 63.8 24.5 42.5 22.6 12.2 23.6 12.6 28.9 22.3 15.0 29.1 52.8 44.3 34.0 33.9 19.4 14.9 55.3 50.5 18.7 16.2 23.2 26.5 15.6 56.2 29.1 7.5 11.8 23.7 14.8 16.8 22.5 19.5 10.4 45.9 24.5 27.4 203.8 56.2 10.6 30.8 15.9 12.8 26.7 21.4 48.2 22.0 50.2 18.6 49.5 34.9 19.9 69.6 25.5 24.3 31.0 18.4 38.0 31.6 22.7 42.4 24.1 51.9 44.3 28.8 17.1 9.7 73.0 27.9 22.7 53.7 22.5 21.6 15.0 40.9 24.8 25.0 27.5 19.0 20.8 16.3 28.4 20.6 56.2 19.1 56.9 16.8 40.5 22.5 20.4 49.9 31.0 18.0 37.5 20.0 30.3 27.2 32.6 30.0 44.6 30.6 21.4 46.0 6.3 23.1 69.1 46.8 53.3 18.7 41.9 84.9 20.5 50.0 12.3 44.9 1.9 2.8 5.1 2.3 2.5 2.9 2.7 2.0 1.7 3.0 3.8 2.1 1.8 14.0 1.9 2.1 3.0 1.6 1.4 54.4 50.9 49.4 63.8 52.8 44.3 55.3 50.5 56.2 45.9 56.2 48.2 13.0 3.2 11.2 12.7 15.0 14.4 18.5 21.8 19.4 14.1 16.2 13.3 5.3 20.0 13.7 12.9 12.5 49.6 9.5 26.2 15.6 39.0 193.1 14.4 14.8 15.8 16.2 14.7 9.3 26.6 69.7 13.4 15.3 10.0 2.5 10.3 11.4 10.8 23.2 20.2 9.0 16.8 14.2 15.4 14.5 573.0 19.3 11.5 14.2 6.5 16.4 38.9 11.3 4.5 11.2 30.8 14.6 16.1 13.4 26.7 31.5 19.6 18.6 9.1 26.3 8.7 14.1 175.0 55.9 16.9 15.2 119.6 10.8 16.6 15.1 23.3 GPR27 SREB1 ENSG00000170837 "G protein-coupled receptor 27" Q9NS67 3 71753855-71756496 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 22.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 10.3;Breast myoepithelial cells: 7.5;Collecting duct cells: 12.9;Glandular and luminal cells: 8.1;monocytes: 8.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "eosinophil: 2.8;neutrophil: 7.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 7.2" "Cell line enhanced" "Detected in some" "EFO-21: 17.9;HL-60: 17.5;MCF7: 14.6;NTERA-2: 28.9;RPTEC TERT1: 13.6;SH-SY5Y: 10.9;T-47d: 9.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029395 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Plasma membrane, Actin filaments, Cytosol" "HPA029395: AB_10602907" "prognostic favorable (5.63e-4)" "unprognostic (2.99e-1)" "unprognostic (3.23e-2)" "unprognostic (3.22e-1)" "unprognostic (7.14e-3)" "unprognostic (1.50e-2)" "unprognostic (2.17e-2)" "unprognostic (1.18e-2)" "unprognostic (3.22e-1)" "prognostic favorable (1.21e-6)" "unprognostic (2.97e-3)" "unprognostic (4.97e-2)" "unprognostic (1.51e-2)" "unprognostic (1.21e-2)" "unprognostic (2.71e-2)" "unprognostic (1.45e-2)" "unprognostic (6.79e-2)" 1.4 4.0 21.3 1.5 22.9 15.7 3.9 13.0 19.7 3.5 7.4 1.6 0.3 5.0 2.8 3.7 6.8 1.0 3.4 19.9 20.6 3.2 0.1 1.4 0.2 18.0 18.3 4.4 3.1 17.3 9.2 1.2 16.2 5.1 0.5 1.8 1.4 4.3 0.7 2.1 0.7 2.9 19.7 3.3 2.0 4.7 22.9 0.5 6.2 1.9 0.2 2.0 2.3 18.9 0.0 1.1 1.9 2.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 17.9 0.0 0.8 0.1 4.3 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.1 17.5 0.9 0.0 2.9 0.0 1.2 0.0 0.0 3.7 0.0 0.0 0.0 14.6 1.2 0.2 28.9 0.0 0.0 0.0 0.0 0.0 13.6 7.8 3.0 10.9 3.8 0.0 0.0 3.6 9.9 0.0 0.0 0.0 7.7 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.5 2.8 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.1 7.2 0.0 0.1 0.0 0.0 0.1 21.3 22.9 13.0 19.7 19.9 20.6 18.0 18.3 16.2 19.7 22.9 18.9 0.2 0.0 1.1 0.0 0.1 1.9 4.2 0.0 4.0 10.3 6.5 7.5 3.5 2.8 1.3 12.9 4.2 1.4 0.4 0.2 1.9 0.7 0.2 2.1 4.9 0.4 1.2 1.7 0.0 0.0 1.3 1.2 1.1 8.1 0.0 2.4 0.4 0.0 0.9 0.0 0.0 0.0 0.0 4.4 0.3 0.0 0.9 3.2 0.0 0.0 8.6 0.5 1.0 0.0 0.0 0.3 0.1 1.2 0.0 5.6 0.0 0.1 1.5 0.4 0.0 2.3 1.7 0.2 4.8 4.7 1.7 0.3 0.7 0.5 0.3 2.0 GPX8 "EPLA847, UNQ847" ENSG00000164294 "Glutathione peroxidase 8 (putative)" Q8TED1 5 55160167-55167297 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 62.7;Extravillous trophoblasts: 218.9;Fibroblasts: 76.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 254.4;fHDF/TERT166: 246.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036720 Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "Actin filaments" "HPA036720: AB_2675269" "unprognostic (4.85e-2)" "unprognostic (1.23e-2)" "unprognostic (6.53e-2)" "unprognostic (1.92e-2)" "unprognostic (2.31e-2)" "unprognostic (9.74e-3)" "unprognostic (1.78e-2)" "unprognostic (1.63e-3)" "unprognostic (2.07e-2)" "unprognostic (4.34e-2)" "unprognostic (4.31e-2)" "unprognostic (8.68e-2)" "prognostic unfavorable (5.13e-9)" "prognostic unfavorable (7.96e-4)" "unprognostic (8.11e-2)" "unprognostic (1.16e-2)" "unprognostic (2.63e-2)" 13.3 6.1 1.2 12.5 1.2 0.1 12.6 1.2 1.6 37.1 6.9 7.3 2.9 21.1 21.9 6.2 14.3 17.0 11.2 1.0 1.7 6.5 2.2 6.9 3.8 1.5 1.1 27.3 4.6 9.3 2.4 39.7 1.4 10.2 8.4 1.3 7.2 15.8 1.5 5.0 4.1 27.2 1.5 4.0 5.6 5.6 1.2 1.3 22.3 6.3 3.0 17.8 9.8 3.6 37.2 39.0 75.3 77.0 180.7 223.9 36.6 179.8 254.4 97.0 192.7 3.2 82.1 0.0 199.0 246.4 86.5 28.2 46.0 51.5 131.5 0.5 17.3 2.1 49.1 6.9 64.4 0.0 0.0 157.5 60.8 68.3 35.5 126.5 122.7 0.0 1.1 0.1 137.4 14.4 0.0 0.0 32.6 1.0 42.8 0.1 40.2 0.0 65.9 1.3 0.1 1.4 56.6 4.6 68.0 80.8 56.6 3.4 102.7 63.6 65.6 84.5 102.3 0.1 0.5 0.5 103.0 0.1 118.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 1.2 1.2 1.6 1.0 1.7 1.5 1.1 1.4 1.5 1.2 3.6 10.9 0.0 1.1 0.3 0.3 7.1 6.0 38.3 9.1 0.2 8.9 6.1 4.3 0.0 33.3 25.8 0.0 49.5 0.2 0.5 5.9 13.7 0.4 6.5 62.7 18.6 0.0 0.0 0.1 38.8 218.9 76.6 2.6 4.9 4.5 30.9 19.2 0.2 10.2 0.0 0.1 4.7 4.1 0.0 6.9 0.6 51.3 1.1 24.9 5.6 1.1 7.9 0.0 0.0 0.1 15.8 0.3 39.9 1.4 2.6 0.1 0.5 36.5 0.3 13.1 20.1 38.2 0.1 0.4 3.1 6.1 13.3 1.8 29.9 0.9 2.4 GSC ENSG00000133937 "Goosecoid homeobox" P56915 14 94768223-94770113 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 3.8;breast: 6.8" "Cell type enhanced" "Detected in some" "Adipocytes: 3.5;Breast myoepithelial cells: 2.2;Ductal cells: 3.0;Exocrine glandular cells: 2.4;Fibroblasts: 9.2;Langerhans cells: 2.3;Skeletal myocytes: 2.6;Smooth muscle cells: 4.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 9 "hypothalamus: 1.4" "Immune cell enriched" "Detected in single" 8 "gdT-cell: 3.6" "Lineage enriched" "Detected in single" 18 "T-cells: 3.6" "Cell line enhanced" "Detected in some" "AN3-CA: 1.3;HEK 293: 2.0;MCF7: 3.2;REH: 3.3;SH-SY5Y: 3.5;T-47d: 2.5;U-251 MG: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB079923, CAB079924" Supported "Nucleoplasm,Nuclear speckles,Actin filaments" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: REH - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear speckles" "Actin filaments" "CAB079923: , CAB079924: " "unprognostic (2.11e-2)" "unprognostic (1.04e-1)" "unprognostic (3.15e-2)" "unprognostic (5.11e-2)" "unprognostic (2.49e-1)" "unprognostic (3.70e-3)" "unprognostic (1.82e-3)" "unprognostic (3.87e-2)" "unprognostic (3.41e-1)" "unprognostic (2.74e-1)" "unprognostic (1.39e-1)" "unprognostic (2.28e-1)" "unprognostic (5.18e-10)" "unprognostic (4.96e-2)" "unprognostic (1.31e-1)" "unprognostic (1.52e-1)" "unprognostic (1.16e-1)" 3.8 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.1 0.4 0.1 0.1 0.2 0.0 0.1 0.4 0.0 0.5 0.0 1.4 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.6 0.1 0.4 0.0 0.0 0.7 0.0 0.0 0.9 0.5 1.2 0.8 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.2 1.6 2.2 0.1 0.3 0.2 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.3 0.0 0.0 0.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 3.2 0.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.0 0.6 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.1 0.0 0.0 0.1 0.0 3.5 0.0 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.0 1.0 2.2 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 3.0 0.1 0.3 0.1 0.4 0.0 0.0 0.0 2.4 0.0 9.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.2 0.0 0.0 0.6 0.0 1.0 0.0 0.0 0.7 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 2.6 4.6 0.0 1.2 0.0 0.9 0.0 0.4 0.0 0.0 0.1 GSN DKFZp313L0718 ENSG00000148180 Gelsolin P06396 9 121207794-121332843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cilium biogenesis/degradation" "Actin capping, Actin-binding" "Amyloidosis, Cancer-related genes, Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 2486.9" "Cell type enhanced" "Detected in all" "Adipocytes: 1649.5;Fibroblasts: 4145.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 1135.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1313.9;HaCaT: 533.6" "Region enriched" "Detected in all" 4 "white matter: 869.2" "Low region specificity" "Detected in all" "CAB010823, CAB016728, CAB036009, HPA054026" Supported Supported "Actin filaments" "Secreted to blood" NA NA 112000000000 240000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Actin filaments" "CAB010823: , CAB016728: , CAB036009: , HPA054026: AB_2682347" "unprognostic (3.25e-2)" "unprognostic (4.44e-3)" "unprognostic (1.22e-1)" "unprognostic (3.10e-3)" "unprognostic (4.23e-2)" "unprognostic (4.85e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-1)" "unprognostic (1.22e-1)" "unprognostic (1.20e-1)" "unprognostic (6.54e-2)" "unprognostic (6.56e-2)" "unprognostic (3.06e-2)" "unprognostic (8.01e-3)" "unprognostic (4.98e-2)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.79e-5)" 1892.9 162.5 169.7 109.7 317.4 175.0 1244.6 291.2 213.0 577.4 155.6 867.4 152.0 767.7 108.2 435.1 663.2 226.1 2486.9 163.4 219.8 153.1 40.6 308.7 93.2 380.9 284.6 303.8 140.7 70.9 260.6 79.0 354.7 344.0 204.6 57.8 508.7 400.9 420.4 612.9 384.1 350.0 270.6 136.5 469.7 78.1 279.0 99.7 702.6 687.8 87.3 897.2 655.5 376.1 38.4 60.9 39.0 129.8 1313.9 351.8 26.4 130.9 264.7 30.1 56.5 64.2 130.1 3.0 36.6 182.8 48.5 533.6 3.2 84.3 16.9 6.5 7.6 31.2 57.1 167.5 32.0 7.0 146.0 140.0 84.9 51.7 34.4 83.1 120.4 6.1 10.4 5.3 137.0 81.1 0.4 304.4 12.7 76.2 45.1 8.4 13.1 4.3 156.4 63.4 7.7 10.4 60.9 62.5 197.2 84.6 245.3 158.8 217.4 100.0 33.2 10.4 12.8 1.8 2.0 3.2 105.3 18.2 278.1 302.9 122.0 1135.9 1.9 84.9 0.8 17.6 0.8 1.4 345.3 6.7 0.8 0.7 307.1 217.8 23.7 243.2 4.2 105.4 169.7 317.4 291.2 213.0 163.4 219.8 380.9 284.6 354.7 270.6 279.0 376.1 1649.5 147.4 55.7 82.3 22.7 341.2 278.1 252.7 103.0 7.5 120.8 212.0 272.0 85.8 354.3 121.4 77.2 55.8 74.9 557.7 105.7 258.5 9.9 141.9 163.1 724.8 63.1 17.2 17.1 202.3 94.3 4145.2 322.7 220.6 104.0 31.8 273.5 16.5 492.6 1.7 9.0 762.9 512.7 139.0 798.7 20.2 588.7 273.7 537.2 155.5 487.5 220.6 55.6 33.2 443.1 315.8 590.5 671.8 24.1 91.4 77.4 39.8 583.7 86.5 611.4 362.4 740.4 8.7 13.7 175.9 299.1 84.0 58.7 34.3 52.2 144.7 H1-0 "H1.0, H1F0, H1FV" ENSG00000189060 "H1.0 linker histone" P07305 22 37805093-37807436 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 660.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 51.4;Cytotrophoblasts: 42.9;Extravillous trophoblasts: 125.7;Hofbauer cells: 73.2;Syncytiotrophoblasts: 219.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 8.1;granulocytes: 17.1;monocytes: 11.7" "Cell line enhanced" "Detected in many" "OE19: 662.8;U-2 OS: 823.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000843 Supported Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus,Actin filaments" Yes No 120000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nuclear bodies" "Golgi apparatus, Actin filaments" "HPA000843: AB_1079062" "unprognostic (1.29e-2)" "unprognostic (1.68e-1)" "unprognostic (1.69e-2)" "unprognostic (1.27e-1)" "unprognostic (3.31e-3)" "unprognostic (1.19e-1)" "unprognostic (2.18e-1)" "unprognostic (3.85e-1)" "unprognostic (7.68e-2)" "unprognostic (1.86e-1)" "unprognostic (5.95e-3)" "unprognostic (4.86e-3)" "prognostic favorable (7.68e-7)" "unprognostic (3.40e-1)" "unprognostic (1.47e-1)" "unprognostic (1.37e-3)" "unprognostic (1.73e-1)" 89.8 53.5 56.6 36.7 55.4 660.5 121.4 72.5 64.1 218.3 42.5 146.2 129.9 168.2 43.5 230.6 119.7 56.3 86.5 55.4 67.1 292.8 179.3 72.4 24.4 58.4 54.2 120.7 125.9 93.2 58.2 80.0 57.7 151.7 120.0 39.9 155.3 40.2 216.2 228.6 137.1 97.7 52.6 36.7 131.2 42.4 58.3 136.2 93.9 93.5 46.6 85.6 194.9 55.8 159.6 67.9 206.0 91.8 53.4 48.4 291.6 126.9 262.3 362.6 512.6 278.1 247.3 0.2 31.1 106.3 84.1 303.8 0.0 87.2 256.0 0.9 15.3 268.2 25.3 187.4 185.8 0.1 0.7 45.4 152.4 182.3 203.2 4.0 97.8 60.4 0.1 0.5 28.5 263.3 45.4 26.5 80.2 662.8 329.9 74.6 122.6 56.1 58.0 42.7 47.3 263.9 349.9 235.4 473.9 91.8 184.2 167.1 65.4 27.4 823.3 122.7 25.9 0.7 18.5 1.2 33.5 95.9 80.3 17.1 9.9 15.7 0.1 11.7 0.1 0.0 1.0 0.2 8.1 0.1 2.8 0.4 5.4 0.1 10.3 7.4 0.2 6.9 56.6 55.4 72.5 64.1 55.4 67.1 58.4 54.2 57.7 52.6 58.3 55.8 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.4 0.0 0.0 0.0 0.0 42.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 125.7 25.2 0.0 0.0 0.0 0.0 0.0 0.0 73.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 219.7 0.0 0.0 0.0 0.0 HELZ "DHRC, HUMORF5, KIAA0054" ENSG00000198265 "Helicase with zinc finger" P42694 17 67070444-67245989 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028276 Approved Approved "Nucleoli,Nucleoli rim,Plasma membrane,Actin filaments" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoli, Nucleoli rim" "Plasma membrane, Actin filaments" "HPA028276: AB_10601814" "unprognostic (3.16e-1)" "unprognostic (2.10e-2)" "unprognostic (7.56e-3)" "unprognostic (1.29e-1)" "unprognostic (4.83e-2)" "unprognostic (4.71e-2)" "unprognostic (5.85e-2)" "unprognostic (5.31e-2)" "unprognostic (3.60e-2)" "unprognostic (1.16e-1)" "unprognostic (1.51e-1)" "unprognostic (4.98e-2)" "unprognostic (1.33e-3)" "unprognostic (1.42e-1)" "unprognostic (1.24e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-1)" 6.3 6.6 3.8 8.5 4.9 12.5 6.6 12.0 5.7 7.6 8.4 5.8 4.8 7.4 6.1 4.7 6.1 7.1 6.1 3.6 6.9 6.9 10.9 6.8 9.8 4.1 5.2 12.3 7.8 12.0 6.1 11.2 4.0 6.1 6.6 14.3 6.2 6.2 9.1 4.4 5.9 7.5 3.3 9.1 6.5 10.8 5.5 15.4 8.7 14.0 8.9 6.6 5.0 3.3 10.3 10.0 12.3 12.3 14.8 8.4 18.7 9.0 8.8 11.8 12.4 14.7 7.9 21.2 7.2 12.0 7.4 10.5 23.3 11.3 18.4 8.2 7.3 27.2 10.7 12.5 7.1 22.3 15.6 9.8 10.5 11.4 14.1 8.8 18.1 15.6 19.1 12.9 9.8 13.0 29.0 7.6 7.4 9.2 9.7 19.3 21.6 9.2 9.1 14.3 12.0 11.0 14.3 11.5 15.2 16.9 13.7 13.7 16.1 14.5 16.6 8.0 8.1 10.7 13.4 15.5 7.2 13.7 15.5 2.3 3.3 2.8 5.1 2.8 6.3 1.7 3.1 3.2 2.8 2.8 1.9 2.6 2.3 2.6 1.9 2.2 3.0 2.3 3.8 4.9 12.0 5.7 3.6 6.9 4.1 5.2 4.0 3.3 5.5 3.3 42.9 19.2 37.1 89.1 44.3 32.1 24.6 30.2 29.6 50.8 32.8 23.6 31.1 24.3 30.2 27.6 93.8 32.9 95.8 29.4 7.9 19.1 5.2 49.4 55.8 32.3 38.3 48.8 93.1 14.2 42.8 30.9 38.7 118.5 33.7 51.9 61.8 52.1 31.9 67.3 112.1 30.2 16.2 79.4 28.8 10.5 38.8 55.4 14.2 107.7 62.0 24.0 104.0 134.2 72.6 19.2 23.1 42.9 67.1 29.3 27.7 14.6 26.1 54.9 13.1 45.9 34.0 36.0 26.0 33.6 20.2 18.3 71.0 32.6 26.3 45.8 HS6ST3 ENSG00000185352 "Heparan sulfate 6-O-sulfotransferase 3" Q8IZP7 13 96090107-96839562 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.5" "Group enriched" "Detected in some" 27 "Excitatory neurons: 1308.8;Inhibitory neurons: 893.1;Oligodendrocyte precursor cells: 968.6" "Cancer enhanced" "Detected in many" "breast cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "RT4: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA078257 Approved "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments" "Intracellular and membrane" NA NA 24000 "Cluster 10: Brain - Neuronal signaling" "Cluster 15: RT4 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nuclear membrane" "Plasma membrane, Actin filaments" "HPA078257: AB_2732374" "unprognostic (2.34e-2)" "unprognostic (1.90e-2)" "unprognostic (2.82e-2)" "unprognostic (1.72e-2)" "unprognostic (4.88e-2)" "unprognostic (2.78e-2)" "unprognostic (1.55e-1)" "unprognostic (3.67e-3)" "unprognostic (8.11e-3)" "unprognostic (1.19e-1)" "prognostic favorable (6.12e-5)" "unprognostic (1.54e-4)" "unprognostic (2.24e-1)" "unprognostic (1.57e-3)" "unprognostic (9.89e-2)" 1.4 4.2 1.4 0.2 3.5 0.0 0.3 0.0 9.0 1.8 0.0 0.2 0.4 2.1 2.1 0.4 0.5 0.2 0.9 12.5 7.3 0.8 0.0 0.0 0.0 0.1 5.2 0.1 2.2 2.1 1.9 0.0 0.3 0.2 0.1 2.2 0.0 0.2 1.1 0.5 0.4 1.5 0.3 0.0 0.9 0.3 6.1 0.0 2.4 0.0 0.0 2.7 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 1.1 0.0 1.2 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 17.3 0.9 0.7 0.1 0.1 0.0 0.2 0.5 0.0 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 3.5 0.0 9.0 12.5 7.3 0.1 5.2 0.3 0.3 6.1 0.0 0.0 0.0 0.0 33.6 0.0 0.0 0.0 0.0 0.0 3.9 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.3 0.6 0.1 0.0 0.0 1308.8 0.6 0.1 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 3.3 893.1 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 38.4 0.0 0.9 0.0 968.6 16.5 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.2 0.0 0.1 1.8 0.1 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 ICOS "AILIM, CD278" ENSG00000163600 "Inducible T cell costimulator" Q9Y6W8 2 203936763-203961577 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "bone marrow: 16.5;lymphoid tissue: 20.2" "Cell type enriched" "Detected in some" 12 "T-cells: 81.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 29.1" "Lineage enriched" "Detected in single" 54 "T-cells: 29.1" "Group enriched" "Detected in some" 8 "HEL: 4.6;MOLT-4: 12.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB032575, HPA034865" Approved Approved "Plasma membrane,Actin filaments" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Actin filaments" "CAB032575: AB_2122593, HPA034865: " "unprognostic (2.66e-2)" "unprognostic (2.13e-3)" "unprognostic (4.19e-4)" "unprognostic (2.35e-5)" "unprognostic (1.07e-1)" "prognostic favorable (1.80e-4)" "unprognostic (9.38e-2)" "unprognostic (2.89e-2)" "unprognostic (1.49e-2)" "unprognostic (3.51e-4)" "unprognostic (7.50e-2)" "unprognostic (2.12e-1)" "unprognostic (2.86e-5)" "unprognostic (7.05e-2)" "unprognostic (2.48e-2)" "unprognostic (1.93e-1)" "unprognostic (8.82e-3)" 0.5 0.1 0.0 7.7 0.0 16.5 0.3 0.0 0.0 0.2 0.0 0.7 0.7 0.2 0.1 0.5 0.3 1.4 0.2 0.0 0.0 0.2 0.4 2.6 14.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.5 1.3 0.0 0.4 0.0 0.0 0.2 2.3 0.4 0.0 3.3 1.3 0.2 0.0 20.2 0.4 0.0 16.2 2.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 4.2 0.0 15.1 6.8 0.0 0.0 15.7 7.2 0.1 0.5 0.0 0.0 29.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.3 0.0 3.1 2.9 0.0 0.0 0.0 0.0 1.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.1 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 1.1 2.0 0.2 6.3 0.0 0.4 0.1 0.1 0.0 0.0 0.2 0.0 0.8 4.7 0.1 0.0 3.1 3.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.3 0.0 1.8 0.1 81.2 0.0 0.0 0.1 IFT46 "C11orf2, C11orf60, CFAP32, FLJ21827" ENSG00000118096 "Intraflagellar transport 46" Q9NQC8 11 118544528-118572970 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 64.9;Respiratory ciliated cells: 84.3;Spermatocytes: 44.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037909, HPA057550" Approved Approved "Actin filaments" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 49: Ciliated cells - Cilium organization" "Actin filaments" "HPA037909: AB_10672731, HPA057550: AB_2683464" "unprognostic (8.77e-2)" "unprognostic (1.22e-1)" "unprognostic (2.79e-1)" "unprognostic (2.35e-3)" "unprognostic (6.76e-2)" "unprognostic (1.55e-2)" "unprognostic (1.07e-1)" "unprognostic (3.29e-2)" "unprognostic (3.75e-3)" "unprognostic (1.47e-1)" "unprognostic (1.37e-1)" "unprognostic (3.61e-1)" "unprognostic (9.02e-3)" "unprognostic (1.42e-1)" "unprognostic (2.48e-1)" "unprognostic (6.53e-2)" "unprognostic (2.41e-1)" 14.7 19.4 29.0 8.8 29.7 5.6 26.8 33.9 35.8 23.1 37.3 18.6 7.7 19.4 24.8 13.7 66.8 16.4 21.3 28.5 32.5 26.9 17.0 15.1 11.0 32.1 37.2 27.2 16.7 18.4 28.9 8.7 31.8 20.9 11.1 35.7 15.9 20.2 17.9 13.5 10.3 20.7 31.5 11.8 15.0 28.1 31.4 16.0 27.5 17.6 12.8 16.0 16.7 32.1 15.6 18.4 26.1 16.9 42.8 35.7 3.2 31.9 46.2 29.3 27.6 22.5 28.8 23.8 46.1 38.6 7.2 22.1 26.7 31.8 34.4 9.1 21.8 49.2 9.0 8.6 32.0 11.8 13.8 32.4 37.0 49.0 46.2 26.6 28.9 32.1 27.4 16.0 37.3 71.7 31.3 15.6 7.7 27.3 38.0 25.6 20.0 19.0 23.5 21.4 16.7 18.3 23.2 29.9 20.1 15.0 46.2 16.7 24.6 31.6 20.2 18.4 12.0 9.9 14.3 26.7 16.0 21.2 23.2 2.8 5.2 5.9 8.6 4.3 9.9 11.1 7.6 7.9 6.9 8.3 9.2 5.5 1.6 11.0 4.2 7.0 9.9 4.8 29.0 29.7 33.9 35.8 28.5 32.5 32.1 37.2 31.8 31.5 31.4 32.1 5.5 9.6 10.3 10.4 4.9 4.0 8.3 14.4 8.0 12.5 11.6 8.4 14.5 10.0 15.4 11.0 18.8 5.3 3.8 1.6 5.9 17.1 20.5 64.9 11.7 9.3 4.2 6.6 8.7 11.6 7.1 9.5 4.1 9.6 12.0 10.2 8.6 5.9 8.8 1.7 8.9 4.3 14.2 2.4 3.5 15.7 10.2 3.1 1.8 5.6 5.5 14.8 2.1 4.0 6.4 10.2 4.2 18.4 6.1 6.1 3.4 14.3 84.3 16.5 0.0 11.3 11.5 44.9 38.4 6.5 7.0 1.9 4.2 9.8 5.3 3.9 INTS6 "DBI-1, DDX26, DDX26A, DICE1, HDB, INT6, Notchl2" ENSG00000102786 "Integrator complex subunit 6" Q9UL03 13 51354077-51454264 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Skeletal myocytes: 374.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001552, HPA001846" Supported Supported "Nucleoplasm,Actin filaments" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Actin filaments" "HPA001552: AB_1078659, HPA001846: AB_1847669" "unprognostic (1.99e-1)" "unprognostic (4.81e-2)" "unprognostic (3.58e-2)" "unprognostic (4.94e-2)" "unprognostic (1.08e-1)" "unprognostic (1.18e-1)" "unprognostic (1.79e-1)" "unprognostic (1.14e-1)" "unprognostic (3.19e-2)" "unprognostic (6.70e-2)" "unprognostic (9.16e-2)" "unprognostic (3.32e-2)" "unprognostic (3.18e-2)" "unprognostic (2.80e-1)" "unprognostic (5.83e-2)" "unprognostic (2.36e-1)" "unprognostic (6.26e-2)" 14.0 14.8 7.7 16.6 9.1 15.0 11.8 17.8 10.0 12.8 11.1 12.1 11.2 14.8 11.6 19.7 10.5 14.0 14.0 9.5 9.0 12.9 28.2 10.0 20.9 9.1 8.2 13.7 37.9 15.9 9.4 14.8 10.1 10.7 10.9 18.9 11.5 9.7 8.4 15.2 13.1 13.4 8.2 15.2 15.4 62.1 8.3 20.7 15.7 16.7 17.3 16.0 11.7 18.2 17.6 13.8 32.8 17.2 17.2 40.6 17.8 36.3 33.5 35.9 25.1 16.2 46.9 20.3 8.5 26.3 22.7 31.0 45.2 20.0 50.6 39.3 12.6 38.7 21.9 19.1 41.6 43.4 33.6 25.3 36.5 33.7 50.7 46.1 31.3 25.5 24.1 30.2 35.9 13.3 26.9 26.8 23.5 51.6 12.4 20.2 23.4 20.3 26.8 11.6 18.2 18.0 36.5 30.2 24.3 24.2 15.4 41.5 17.7 22.1 15.2 23.6 20.8 26.5 21.7 33.0 18.2 22.7 39.2 8.0 2.0 3.2 5.9 1.3 6.7 3.9 4.0 5.0 2.1 4.0 5.6 6.5 5.5 5.0 1.5 4.6 5.0 2.4 7.7 9.1 17.8 10.0 9.5 9.0 9.1 8.2 10.1 8.2 8.3 18.2 241.6 25.6 49.5 75.4 121.4 76.3 68.7 12.0 162.8 58.3 157.5 215.6 78.4 47.1 18.3 22.0 118.9 81.4 164.8 107.2 15.6 23.4 94.3 48.4 67.4 94.5 76.0 29.5 82.2 26.3 47.5 127.4 61.7 64.5 48.2 71.4 57.8 37.3 34.8 45.4 66.7 94.8 12.2 44.2 60.1 81.3 44.1 97.5 23.2 78.7 33.3 55.9 53.5 94.0 118.9 25.9 59.7 31.6 90.9 53.7 77.1 11.9 12.9 74.9 26.3 374.7 119.4 122.4 40.5 161.3 72.5 73.7 137.8 66.5 90.3 68.0 IQCG "CFAP122, DKFZp434B227, DRC9" ENSG00000114473 "IQ motif containing G" Q9H095 3 197889077-197960142 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 52.8;testis: 43.9" "Cell type enhanced" "Detected in all" "Early spermatids: 255.0;Endometrial ciliated cells: 176.3;Late spermatids: 489.4;Respiratory ciliated cells: 322.2;Spermatocytes: 122.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "T-47d: 32.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042787, HPA051981" Enhanced Approved "Actin filaments,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Actin filaments" Cytosol "HPA042787: AB_10797021, HPA051981: AB_2732572" "unprognostic (1.50e-2)" "unprognostic (6.20e-3)" "unprognostic (6.20e-2)" "unprognostic (1.10e-2)" "unprognostic (2.51e-2)" "unprognostic (9.20e-2)" "unprognostic (1.05e-1)" "unprognostic (4.89e-2)" "unprognostic (4.35e-2)" "unprognostic (1.86e-1)" "unprognostic (7.54e-2)" "unprognostic (1.79e-1)" "unprognostic (2.94e-2)" "unprognostic (9.15e-2)" "unprognostic (1.73e-1)" "unprognostic (2.72e-3)" "unprognostic (7.75e-2)" 6.0 5.2 8.9 3.3 9.7 3.2 5.8 8.4 9.5 5.9 25.2 3.2 2.6 4.6 10.0 4.0 52.8 4.6 4.4 8.7 10.6 6.4 3.7 9.1 3.8 15.0 19.8 3.6 2.0 4.4 6.1 3.5 14.1 3.9 3.7 18.1 2.5 4.5 2.0 2.7 2.7 4.3 14.3 3.4 3.7 43.9 10.9 2.9 8.1 2.1 4.2 3.6 2.2 14.6 5.3 5.8 7.3 7.1 15.6 15.7 2.9 6.4 7.1 7.5 7.6 1.2 5.0 1.9 7.0 5.2 9.6 4.9 5.4 5.0 12.0 4.4 3.8 3.2 3.3 2.9 3.6 4.4 5.0 8.1 6.1 8.1 2.6 6.1 3.6 8.8 3.5 7.2 5.8 12.2 2.4 2.1 4.6 7.8 7.6 6.8 4.8 2.6 7.2 2.2 6.4 7.7 10.6 4.3 4.4 6.4 32.2 3.0 3.7 4.8 3.3 14.5 6.7 6.2 18.4 3.1 18.1 6.1 7.8 2.0 3.8 4.3 3.4 2.7 2.2 4.3 2.9 2.3 3.3 1.6 2.7 3.7 2.3 3.3 2.6 2.9 3.1 2.3 8.9 9.7 8.4 9.5 8.7 10.6 15.0 19.8 14.1 14.3 10.9 14.6 7.4 6.4 7.7 16.6 8.5 9.3 3.3 14.8 2.2 13.1 27.9 15.2 11.0 5.7 31.8 5.5 75.0 6.4 10.1 3.1 15.6 7.1 255.0 176.3 15.0 8.2 4.2 4.8 10.1 4.2 5.8 13.1 5.6 16.3 8.8 30.9 5.3 4.2 6.6 10.1 8.8 2.9 26.4 6.0 24.9 489.4 22.7 10.3 14.2 14.0 2.9 13.5 11.3 10.6 13.2 11.9 1.9 23.7 5.7 2.2 1.4 10.4 322.2 43.8 6.6 6.8 18.7 122.7 31.6 5.9 8.9 5.2 10.8 46.5 2.9 2.5 KCNK6 "K2p6.1, TWIK-2" ENSG00000099337 "Potassium two pore domain channel subfamily K member 6" Q9Y257 19 38319845-38332076 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 151.3;Urothelial cells: 131.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 26.2" "Group enriched" "Detected in many" 6 "dendritic cells: 11.4;granulocytes: 26.2;monocytes: 7.2" "Cell line enhanced" "Detected in many" "HEL: 37.6;HMC-1: 40.3;T-47d: 22.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB022637, HPA040184" Uncertain Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "Actin filaments" "CAB022637: , HPA040184: AB_2676876" "unprognostic (7.98e-2)" "unprognostic (2.57e-1)" "unprognostic (1.29e-1)" "prognostic favorable (1.45e-6)" "unprognostic (3.76e-1)" "unprognostic (6.88e-2)" "unprognostic (1.87e-1)" "unprognostic (3.08e-2)" "unprognostic (4.31e-1)" "unprognostic (4.91e-1)" "unprognostic (4.10e-3)" "unprognostic (3.15e-1)" "prognostic unfavorable (1.04e-5)" "unprognostic (1.07e-2)" "unprognostic (3.46e-1)" "unprognostic (5.88e-2)" "unprognostic (4.59e-3)" 3.9 2.4 2.9 7.5 2.4 3.9 5.6 3.0 3.3 29.9 2.7 15.4 4.6 24.0 1.5 30.5 15.7 4.5 6.7 2.7 2.2 3.1 3.0 9.4 5.6 2.9 2.3 9.5 12.5 0.6 1.9 7.0 2.9 6.2 9.4 0.8 14.5 2.4 1.5 19.1 6.8 14.3 2.1 15.6 9.5 2.1 2.8 2.5 1.4 0.7 7.9 13.3 18.2 3.7 9.2 3.3 0.5 0.5 5.1 3.3 0.7 7.8 3.8 2.0 2.7 2.6 9.8 0.6 3.5 11.2 2.1 11.7 4.2 17.7 1.3 0.4 0.3 37.6 1.9 0.4 4.7 2.7 40.3 0.8 15.6 2.5 4.8 10.5 5.3 5.8 0.5 2.8 5.7 20.2 2.4 2.3 0.4 19.4 2.1 3.9 0.5 2.7 7.1 0.8 0.5 0.8 0.8 0.8 0.3 1.8 22.8 10.5 5.8 0.5 4.4 4.1 0.4 1.0 0.2 1.0 0.6 13.4 0.3 26.2 6.9 15.8 1.4 6.2 1.2 1.4 2.0 1.9 11.4 1.1 1.7 1.2 5.0 0.6 7.2 3.1 2.6 2.3 2.9 2.4 3.0 3.3 2.7 2.2 2.9 2.3 2.9 2.1 2.8 3.7 8.7 0.0 10.5 0.0 16.0 43.1 50.6 20.6 20.5 3.3 61.2 32.9 12.1 17.2 15.1 7.3 6.2 2.0 18.5 62.4 0.0 19.1 2.8 32.5 58.8 28.3 12.6 17.9 1.1 47.7 4.0 19.2 28.1 84.8 22.2 72.7 151.3 4.3 39.2 0.0 1.7 64.5 2.0 75.7 61.5 1.2 25.7 47.0 5.4 2.8 62.1 1.2 11.3 0.0 0.9 67.2 39.2 20.3 45.6 41.1 37.6 0.4 7.7 5.9 26.3 3.1 9.3 14.8 3.3 48.0 67.2 2.5 14.8 1.5 26.7 131.5 KCNN1 "hSK1, KCa2.1" ENSG00000105642 "Potassium calcium-activated channel subfamily N member 1" Q92952 19 17951293-18000080 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Transport" "Calmodulin-binding, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 41 "brain: 92.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 12.8;Langerhans cells: 19.8;Skeletal myocytes: 6.8" "Cancer enhanced" "Detected in some" "testis cancer: 3.5" "Group enriched" "Detected in many" 7 "amygdala: 34.8;basal ganglia: 30.6;cerebral cortex: 67.2;hippocampal formation: 92.2;white matter: 30.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "REH: 155.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065938 Approved "Actin filaments,Cytosol" Yes No "Cluster 10: Brain - Neuronal signaling" "Cluster 14: REH - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Actin filaments, Cytosol" "HPA065938: AB_2685582" "unprognostic (7.55e-2)" "unprognostic (4.03e-2)" "unprognostic (1.82e-1)" "unprognostic (7.80e-2)" "unprognostic (1.90e-1)" "unprognostic (8.94e-5)" "unprognostic (3.92e-3)" "unprognostic (1.01e-1)" "unprognostic (8.42e-2)" "unprognostic (3.59e-1)" "unprognostic (2.71e-3)" "unprognostic (3.38e-1)" "unprognostic (5.21e-3)" "unprognostic (2.70e-2)" "unprognostic (1.14e-1)" "unprognostic (7.24e-3)" "unprognostic (3.24e-1)" 0.3 0.2 34.8 0.4 30.6 0.1 0.2 0.0 67.2 0.9 0.0 0.3 0.1 0.6 0.1 0.2 0.1 0.1 1.1 92.2 0.0 0.2 0.0 0.1 0.1 4.4 0.0 1.8 0.1 1.6 1.0 0.0 6.8 0.6 0.0 0.8 0.4 0.2 0.1 0.1 0.2 0.0 0.0 0.1 0.2 2.2 0.0 0.1 0.1 0.0 0.1 0.1 0.2 30.6 0.1 0.6 0.2 6.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.6 0.0 0.5 0.2 5.3 0.0 0.2 0.2 2.5 5.0 0.3 0.1 0.0 0.0 12.8 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.3 0.2 0.0 0.4 0.0 0.0 1.8 0.0 0.1 155.3 0.0 0.2 0.0 0.0 0.2 8.6 0.0 0.0 0.1 0.4 0.3 0.2 0.1 0.0 4.7 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.8 30.6 0.0 67.2 92.2 0.0 4.4 0.0 6.8 0.0 0.0 30.6 0.4 0.0 0.0 3.6 1.1 2.5 3.7 0.0 0.0 2.3 0.2 0.3 0.8 0.0 0.7 0.0 2.1 0.1 1.5 0.2 0.0 0.0 0.2 1.3 1.5 1.9 0.0 0.0 12.8 0.0 0.2 2.6 0.0 1.9 0.0 3.6 0.4 0.2 0.1 0.0 4.4 0.0 0.0 0.3 19.8 0.4 0.9 2.1 5.4 1.9 2.2 1.4 1.0 3.0 0.7 0.2 0.0 1.9 0.7 2.8 0.0 0.2 0.0 1.0 0.0 6.8 1.8 0.6 4.0 0.0 3.8 0.1 1.5 2.2 0.0 1.8 KIF19 "FLJ37300, KIF19A" ENSG00000196169 "Kinesin family member 19" Q2TAC6 17 74326210-74355820 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 16.7;fallopian tube: 12.0;lymphoid tissue: 13.5" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 44.4;Enteroendocrine cells: 23.8;Hepatic stellate cells: 15.4;Intestinal goblet cells: 14.1;Plasma cells: 15.6;Respiratory ciliated cells: 57.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.1" "Lineage enriched" "Detected in single" 22 "T-cells: 2.1" "Cell line enriched" "Detected in single" 9 "SCLC-21H: 4.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043638, HPA073303" Enhanced Approved "Plasma membrane,Actin filaments,Centrosome" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" "Actin filaments, Centrosome" "HPA043638: AB_10962579, HPA073303: AB_2686593" "unprognostic (1.59e-3)" "unprognostic (1.05e-1)" "unprognostic (1.00e-1)" "unprognostic (5.37e-3)" "unprognostic (9.64e-2)" "unprognostic (1.64e-1)" "unprognostic (2.70e-2)" "unprognostic (2.81e-1)" "unprognostic (1.03e-1)" "unprognostic (9.83e-3)" "unprognostic (1.05e-3)" "unprognostic (1.14e-1)" "unprognostic (1.59e-9)" "unprognostic (5.16e-5)" "unprognostic (2.72e-1)" "unprognostic (1.67e-2)" "unprognostic (1.53e-1)" 1.4 0.1 7.5 0.4 10.3 0.2 1.2 4.0 11.4 2.2 3.5 1.7 3.0 0.3 0.0 0.5 12.0 0.4 0.3 7.2 7.4 0.2 0.9 1.9 0.1 7.5 8.0 0.2 1.1 0.0 0.3 0.0 5.9 0.9 0.6 0.1 1.0 0.2 0.4 0.6 2.3 0.4 6.2 13.5 0.7 0.6 7.7 1.0 1.9 0.6 0.1 1.6 1.5 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.2 0.0 0.3 0.6 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.4 7.5 10.3 4.0 11.4 7.2 7.4 7.5 8.0 5.9 6.2 7.7 16.7 1.3 0.0 0.0 2.0 1.3 0.0 0.4 2.5 0.0 1.1 0.1 0.0 1.6 0.0 6.3 0.0 0.0 0.0 3.5 0.8 0.0 0.0 0.5 44.4 0.2 4.2 23.8 0.4 0.0 0.0 3.1 1.0 1.1 0.7 0.0 0.0 15.4 0.1 0.1 0.0 0.1 14.1 4.1 0.6 1.6 0.3 0.0 0.3 3.6 0.0 0.1 5.7 3.1 4.0 3.7 0.0 0.1 0.0 15.6 0.3 0.2 0.0 57.6 0.3 0.0 1.8 1.3 0.2 1.6 0.0 0.1 0.0 2.5 0.2 1.9 0.2 KLC3 "KLC2L, KLCt, KNS2B" ENSG00000104892 "Kinesin light chain 3" Q6P597 19 45333434-45351520 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 26.1;skin 1: 104.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 142.0;Basal prostatic cells: 50.8;Ductal cells: 39.1;Prostatic glandular cells: 66.9;Suprabasal keratinocytes: 183.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 8.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 36.1;HaCaT: 16.2;HBEC3-KT: 10.5;hTCEpi: 12.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA052797, HPA056508" Approved Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Actin filaments" "Nucleoplasm, Cytosol" "HPA052797: AB_2681954, HPA056508: AB_2683159" "unprognostic (4.11e-2)" "unprognostic (3.71e-1)" "unprognostic (3.07e-4)" "prognostic unfavorable (1.46e-4)" "unprognostic (3.47e-3)" "unprognostic (1.13e-1)" "unprognostic (4.42e-2)" "unprognostic (2.29e-1)" "unprognostic (2.53e-1)" "unprognostic (1.75e-2)" "unprognostic (1.49e-1)" "unprognostic (2.74e-2)" "unprognostic (4.79e-3)" "unprognostic (1.94e-1)" "unprognostic (3.55e-3)" "unprognostic (4.14e-1)" "unprognostic (2.37e-1)" 0.3 0.2 0.5 0.3 1.1 3.0 3.3 1.3 0.8 10.0 0.0 0.1 0.1 0.2 2.1 26.1 0.3 0.2 0.2 0.4 0.2 5.9 0.2 0.9 0.3 0.5 0.0 0.2 4.0 4.0 2.7 0.2 0.2 2.6 0.2 1.0 11.6 1.0 0.9 104.1 0.3 0.0 0.0 0.3 0.5 3.7 0.2 1.0 0.7 0.0 1.8 0.2 20.5 0.7 36.1 0.2 0.2 0.4 0.1 0.1 2.8 0.2 0.0 0.0 0.1 3.5 6.5 0.3 2.8 0.0 3.7 16.2 2.2 10.5 0.2 0.8 5.3 0.1 1.1 0.7 0.0 0.3 2.2 0.0 12.9 0.1 2.5 0.4 0.0 0.5 0.6 0.4 0.1 4.7 0.1 0.4 0.8 0.6 1.1 5.6 0.0 0.3 0.3 1.3 4.5 0.7 0.3 7.3 1.0 0.4 6.5 0.1 0.0 0.4 3.6 0.3 0.4 0.7 0.8 0.3 0.2 0.2 0.4 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.2 0.2 0.2 0.4 0.2 0.2 0.2 0.1 0.0 0.5 1.1 1.3 0.8 0.4 0.2 0.5 0.0 0.2 0.0 0.2 0.7 0.2 0.0 2.4 0.3 0.0 142.0 50.8 17.5 14.8 0.8 10.3 25.3 0.4 2.8 7.3 1.8 0.0 0.2 0.2 0.2 9.8 39.1 3.0 0.9 0.3 1.7 0.0 2.7 0.3 3.1 0.7 1.4 0.0 2.4 0.0 6.7 0.4 0.0 0.3 1.7 0.4 0.5 6.1 0.0 10.9 12.0 1.8 0.4 14.2 0.0 0.8 0.7 0.0 0.0 0.0 11.8 0.0 0.4 0.0 66.9 0.0 1.4 3.8 2.0 0.0 1.1 2.5 0.6 11.3 25.6 183.3 0.7 1.0 0.0 0.1 22.0 KLHL14 KIAA1384 ENSG00000197705 "Kelch like family member 14" Q9P2G3 18 32672673-32773023 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 12.7;thyroid gland: 13.8" "Cell type enhanced" "Detected in some" "B-cells: 21.9;Inhibitory neurons: 9.8;Muller glia cells: 19.4;Plasma cells: 45.7" "Group enriched" "Detected in many" 10 "endometrial cancer: 6.8;ovarian cancer: 15.5;thyroid cancer: 7.0" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 90 "memory B-cell: 10.5;naive B-cell: 7.3" "Lineage enriched" "Detected in single" 106 "B-cells: 10.5" "Cell line enhanced" "Detected in some" "EFO-21: 3.1;Hep G2: 15.7;REH: 4.2;RPTEC TERT1: 8.4;SCLC-21H: 3.2;U-698: 4.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 9 "hippocampal formation: 14.9;olfactory bulb: 8.1" HPA024777 Uncertain Supported "Actin filaments,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "Actin filaments" "HPA024777: AB_1852576" "unprognostic (3.93e-2)" "unprognostic (7.87e-2)" "unprognostic (7.09e-2)" "unprognostic (5.61e-3)" "unprognostic (1.87e-1)" "unprognostic (2.16e-6)" "unprognostic (2.14e-1)" "unprognostic (4.30e-2)" "unprognostic (4.81e-2)" "unprognostic (2.32e-3)" "unprognostic (2.32e-1)" "unprognostic (7.64e-2)" "unprognostic (8.91e-2)" "unprognostic (8.03e-2)" "unprognostic (1.97e-1)" "unprognostic (2.65e-2)" "unprognostic (1.43e-2)" 0.5 0.2 0.2 1.8 0.3 2.4 0.5 0.0 0.6 2.9 0.0 0.2 0.2 1.7 1.0 0.2 6.6 0.3 0.1 0.2 0.3 5.0 0.0 0.3 7.1 1.4 2.3 0.3 0.0 6.9 0.3 0.8 0.7 1.4 0.2 4.7 0.4 12.7 0.0 0.1 2.0 0.8 0.8 8.7 0.2 1.0 0.2 0.3 13.8 0.0 5.3 0.6 0.5 0.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 3.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.0 15.7 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 4.2 1.3 0.0 8.4 0.0 3.2 0.4 0.0 0.0 0.7 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.3 0.0 0.6 0.2 0.3 1.4 2.3 0.7 0.8 0.2 0.1 1.3 0.0 0.0 0.3 21.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 7.3 0.0 0.0 0.1 0.0 3.9 0.0 4.5 7.1 0.3 2.0 0.0 0.0 1.6 0.0 0.0 0.0 0.5 1.3 0.0 0.0 0.7 0.0 0.1 1.7 9.8 0.0 0.0 0.6 0.0 1.1 0.0 0.2 0.0 0.0 0.0 19.4 0.0 1.5 0.2 0.0 0.0 0.0 45.7 0.0 0.5 1.1 0.0 0.8 0.0 0.0 0.1 0.7 0.6 0.0 0.3 0.0 0.2 4.7 0.1 0.0 KLHL23 "FLJ37812, MGC22679, MGC2610" ENSG00000213160 "Kelch like family member 23" Q8NBE8 2 169694488-169776989 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 132.5;Cone photoreceptor cells: 89.6;Sertoli cells: 170.9;Smooth muscle cells: 102.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 3.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SCLC-21H: 83.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047593 Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Actin filaments" "HPA047593: " "unprognostic (4.77e-2)" "unprognostic (2.65e-2)" "unprognostic (7.48e-2)" "unprognostic (4.12e-3)" "unprognostic (1.66e-2)" "unprognostic (2.13e-2)" "prognostic unfavorable (2.09e-4)" "unprognostic (4.19e-2)" "unprognostic (3.64e-3)" "unprognostic (1.05e-2)" "unprognostic (4.09e-1)" "unprognostic (4.21e-2)" "prognostic unfavorable (2.43e-5)" "unprognostic (2.61e-1)" "unprognostic (1.45e-1)" "unprognostic (2.70e-1)" "unprognostic (4.87e-3)" 6.9 2.1 8.1 6.1 9.6 1.7 6.2 13.2 9.9 9.6 0.2 20.8 11.1 25.6 4.0 12.0 8.9 6.7 8.0 9.8 7.2 6.6 5.9 5.9 3.1 3.7 5.8 17.9 7.2 6.4 3.3 12.8 4.6 13.6 13.9 13.6 8.0 12.5 12.0 1.6 11.8 25.0 4.0 2.8 5.1 10.9 7.6 11.1 8.1 16.3 2.9 8.7 3.9 6.3 17.0 8.6 64.5 18.3 3.6 1.3 43.7 8.0 6.1 14.4 15.8 18.0 14.4 10.6 6.7 0.8 20.9 2.6 67.7 5.8 21.9 37.7 33.2 31.3 16.9 29.9 5.4 44.2 4.7 2.5 4.7 6.0 10.2 9.3 11.2 38.3 43.5 1.4 4.8 8.2 65.0 17.9 52.7 9.0 6.7 20.7 55.1 1.1 13.1 49.9 83.4 57.1 12.7 1.2 7.8 20.3 10.6 14.2 4.2 5.8 18.6 5.7 13.6 4.9 4.9 47.3 4.5 13.0 9.0 0.0 0.0 0.0 0.7 0.0 0.9 0.3 0.6 0.5 0.1 0.3 1.0 1.0 0.0 3.4 0.0 0.9 0.8 0.3 8.1 9.6 13.2 9.9 9.8 7.2 3.7 5.8 4.6 4.0 7.6 6.3 13.7 3.2 8.7 0.0 1.1 1.5 6.9 2.8 7.4 132.5 15.0 17.1 52.9 14.3 6.7 0.0 89.6 5.6 3.8 14.6 3.9 15.6 4.6 2.4 12.8 12.6 31.8 9.7 0.0 30.5 9.6 11.2 4.1 5.5 0.0 27.5 7.5 11.8 0.9 40.4 0.0 21.2 28.5 0.8 1.9 3.7 2.5 1.3 0.0 0.0 0.2 14.6 5.2 0.0 0.0 16.1 13.6 8.6 0.4 17.2 9.7 16.9 4.9 34.8 170.9 11.4 102.6 3.4 20.9 4.7 1.0 1.2 5.5 13.8 20.9 4.1 LAD1 ENSG00000159166 "Ladinin 1" O00515 1 201380833-201399915 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 362.1;skin 1: 215.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 174.7;Ductal cells: 178.0;monocytes: 248.6;Pancreatic endocrine cells: 227.0;Proximal enterocytes: 214.7;Squamous epithelial cells: 265.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 159.9;CAPAN-2: 158.5;HaCaT: 220.4;HBEC3-KT: 190.3;hTCEpi: 181.5;MCF7: 218.3;OE19: 246.5;RT4: 164.7;SK-BR-3: 250.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA007256, HPA028732" Enhanced Enhanced "Actin filaments" "Secreted to extracellular matrix" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Actin filaments" "HPA007256: AB_1852681, HPA028732: AB_10602916" "unprognostic (4.95e-2)" "unprognostic (2.05e-1)" "unprognostic (3.82e-1)" "unprognostic (7.55e-3)" "unprognostic (4.66e-2)" "unprognostic (7.41e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.06e-1)" "unprognostic (1.50e-1)" "unprognostic (1.71e-2)" "unprognostic (9.11e-2)" "unprognostic (2.31e-2)" "unprognostic (3.71e-2)" "unprognostic (1.18e-1)" "unprognostic (6.40e-2)" "unprognostic (3.28e-1)" 0.5 0.1 0.0 15.9 0.1 0.1 15.8 0.0 0.2 65.4 0.0 67.6 75.6 5.0 11.0 362.1 14.7 50.2 8.4 0.2 0.6 38.6 21.6 10.6 2.9 0.0 0.0 0.4 50.7 2.4 0.7 4.1 0.0 15.7 51.0 0.0 51.9 22.6 5.1 215.4 74.5 2.9 0.0 1.4 66.9 0.3 0.0 6.2 3.5 0.2 47.7 71.4 135.2 0.0 159.9 1.3 0.0 0.3 0.0 0.0 57.0 0.0 0.0 0.1 0.1 127.3 158.5 0.0 8.9 0.0 0.0 220.4 0.0 190.3 0.1 0.2 0.0 0.0 0.1 79.3 0.0 0.1 0.2 0.1 181.5 0.1 36.8 0.0 0.1 0.0 0.1 0.7 0.1 218.3 0.2 0.4 3.7 246.5 2.6 0.2 7.4 2.3 126.0 164.7 9.1 0.2 0.1 250.6 3.1 5.4 37.6 0.4 0.0 0.1 0.5 0.5 0.6 0.1 0.4 0.2 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.2 35.4 0.0 0.9 88.5 112.1 47.2 46.7 0.0 15.4 14.1 2.1 110.1 31.3 31.3 0.0 3.8 0.5 174.7 45.0 178.0 1.1 26.2 2.6 1.6 18.1 0.0 0.0 121.9 5.9 2.6 85.1 34.5 0.0 0.0 0.4 9.0 0.5 0.0 0.0 53.8 18.3 0.6 16.0 3.6 0.0 2.6 10.6 0.0 248.6 0.0 0.0 0.0 0.0 227.0 109.6 0.4 2.9 77.1 214.7 71.8 4.8 0.0 0.0 0.0 3.2 0.0 0.3 265.6 152.7 10.4 1.5 0.0 136.2 150.2 LCP1 "CP64, L-PLASTIN, LC64P, PLS2" ENSG00000136167 "Lymphocyte cytosolic protein 1" P13796 13 46125920-46211871 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 709.0;epididymis: 402.7;lymphoid tissue: 605.1" "Cell type enhanced" "Detected in many" "dendritic cells: 438.4;granulocytes: 309.1;Hofbauer cells: 264.4;Kupffer cells: 401.2;Langerhans cells: 337.6;Late spermatids: 290.9;Macrophages: 466.1;monocytes: 535.7;NK-cells: 471.7;T-cells: 375.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 875.8;HDLM-2: 799.3;HL-60: 850.7;HMC-1: 861.7;JURKAT: 792.7;NB-4: 789.2;THP-1: 840.5;U-698: 1105.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019493, CAB020673" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA 1800000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "Actin filaments" "CAB020673: , HPA019493: AB_1855457" "unprognostic (2.79e-2)" "unprognostic (8.20e-3)" "unprognostic (1.19e-2)" "unprognostic (3.95e-3)" "unprognostic (1.19e-1)" "unprognostic (2.84e-2)" "unprognostic (2.70e-1)" "unprognostic (4.99e-2)" "unprognostic (6.70e-3)" "unprognostic (2.54e-1)" "unprognostic (5.47e-2)" "unprognostic (3.63e-1)" "unprognostic (3.32e-3)" "unprognostic (2.51e-1)" "unprognostic (1.02e-1)" "unprognostic (7.50e-2)" "unprognostic (2.92e-1)" 85.9 31.1 11.3 396.9 13.1 709.0 43.9 13.9 30.9 28.5 16.8 54.7 42.4 27.4 402.7 29.5 21.5 76.4 14.5 11.3 14.2 13.1 89.0 173.8 563.5 19.7 18.9 10.0 12.2 12.6 4.3 67.2 21.3 184.5 71.2 4.9 44.4 24.3 7.1 40.6 62.3 60.4 18.6 375.2 53.2 33.2 24.8 499.8 23.6 17.8 605.1 133.0 7.7 29.9 36.1 0.2 1.9 0.0 0.0 0.0 409.8 0.1 1.2 3.9 2.9 237.4 1.4 875.8 179.5 0.0 249.1 1.7 0.1 0.6 3.9 799.3 202.9 187.6 0.4 1.1 0.9 850.7 861.7 2.3 0.1 1.4 1.2 0.3 0.0 792.7 100.4 569.7 0.0 2.8 624.8 789.2 1.0 0.4 8.2 451.6 1.6 638.2 0.0 233.8 2.8 7.5 1.9 91.8 6.4 25.0 6.4 840.5 3.1 22.0 13.6 1.5 25.5 135.3 292.5 1105.7 17.0 530.9 3.6 1007.3 1559.5 810.8 915.7 1806.2 822.0 342.3 539.6 761.2 1134.5 251.6 330.2 560.5 1908.6 650.6 1826.1 297.5 598.1 3644.2 11.3 13.1 13.9 30.9 11.3 14.2 19.7 18.9 21.3 18.6 24.8 29.9 7.4 32.1 73.2 0.3 185.2 12.0 1.2 0.0 1.8 0.4 10.3 11.7 4.2 5.7 18.0 3.7 0.0 9.8 438.4 0.2 0.0 16.9 113.1 4.7 42.8 9.6 1.2 63.9 0.5 16.3 68.3 10.9 19.9 7.0 309.1 0.7 12.5 24.0 264.4 0.0 0.5 0.5 0.0 401.2 337.6 290.9 1.2 466.1 23.2 17.8 535.7 23.7 471.7 0.5 1.5 6.8 2.4 1.9 102.4 42.0 0.1 1.5 13.8 1.2 0.0 3.1 6.2 2.7 1.6 2.2 11.8 13.5 375.3 0.5 0.4 4.0 LIMA1 EPLIN ENSG00000050405 "LIM domain and actin binding 1" Q9UHB6 12 50175788-50283546 "Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 553.9;Basal prostatic cells: 646.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 523.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023871, HPA052645" Enhanced Enhanced "Plasma membrane,Actin filaments,Focal adhesion sites,Cytosol" NA NA 90000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "Focal adhesion sites, Cytosol" "HPA023871: AB_1852875, HPA052645: AB_2681898" "unprognostic (6.22e-2)" "unprognostic (9.39e-3)" "unprognostic (8.13e-2)" "unprognostic (1.42e-1)" "unprognostic (8.08e-2)" "prognostic unfavorable (1.76e-6)" "unprognostic (1.63e-1)" "unprognostic (2.29e-1)" "unprognostic (2.28e-2)" "unprognostic (2.65e-1)" "unprognostic (1.28e-3)" "unprognostic (6.27e-2)" "prognostic favorable (2.79e-4)" "unprognostic (7.12e-2)" "unprognostic (9.26e-3)" "unprognostic (1.46e-1)" "unprognostic (1.43e-1)" 122.2 47.1 11.9 39.9 13.6 4.2 89.4 40.3 16.4 63.3 12.3 125.6 112.1 56.8 33.2 37.1 47.9 69.3 31.9 11.7 13.1 48.7 20.7 62.5 32.6 15.4 13.8 38.6 31.1 31.0 24.0 50.6 17.3 45.7 130.5 32.2 47.2 42.2 21.9 47.3 121.8 48.6 13.3 40.8 96.8 16.2 13.1 38.1 33.3 28.3 33.8 96.7 53.2 16.3 154.3 4.5 47.2 69.7 211.9 211.0 177.7 377.2 264.4 296.9 235.8 57.7 220.2 6.8 34.1 523.4 99.7 170.8 42.8 348.7 258.1 98.1 45.1 64.2 16.2 20.5 135.3 23.2 87.5 142.2 100.8 104.6 297.8 89.0 106.2 28.3 45.6 30.3 96.9 26.5 29.0 7.1 24.3 81.0 20.5 28.7 115.2 2.4 68.7 180.3 35.2 75.4 51.5 102.7 166.6 50.0 49.0 14.1 166.7 126.5 98.0 118.4 62.1 16.5 2.0 28.0 137.6 25.3 55.6 0.2 0.2 1.5 6.6 1.1 2.6 0.2 8.2 8.1 4.9 0.6 3.3 6.0 0.1 5.9 2.7 1.2 15.3 3.0 11.9 13.6 40.3 16.4 11.7 13.1 15.4 13.8 17.3 13.3 13.1 16.3 123.2 44.8 91.2 13.4 4.8 553.9 646.1 175.4 283.4 14.6 62.2 73.0 7.3 61.5 179.1 119.5 160.6 128.1 15.5 413.7 15.6 145.6 67.1 75.7 183.9 91.8 122.8 17.5 12.9 307.6 376.9 170.9 126.9 132.6 24.7 15.9 117.8 19.8 34.4 6.7 30.1 138.0 187.2 11.7 59.3 11.7 75.5 19.3 90.7 41.2 9.9 22.7 28.8 78.9 48.4 219.0 244.5 77.5 6.9 221.6 214.8 22.3 67.8 95.4 65.7 54.9 118.0 30.8 10.4 100.0 291.5 64.0 33.3 62.4 244.3 385.1 LIMCH1 "DKFZP686A01247, LIMCH1A, LMO7B" ENSG00000064042 "LIM and calponin homology domains 1" Q9UPQ0 4 41359607-41700044 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 203.9;tongue: 277.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 650.7;Excitatory neurons: 434.8;Inhibitory neurons: 551.3;Oligodendrocytes: 1102.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "myeloid DC: 1.3" "Lineage enriched" "Detected in single" 8 "dendritic cells: 1.3" "Cell line enhanced" "Detected in many" "EFO-21: 106.2;HeLa: 180.0;hTERT-RPE1: 146.9;RT4: 181.0;SiHa: 102.5;WM-115: 144.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004184, HPA063840" Uncertain Approved "Actin filaments" NA NA 5600 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Actin filaments" "HPA004184: AB_1078673, HPA063840: AB_2685133" "prognostic unfavorable (5.55e-6)" "unprognostic (3.63e-2)" "unprognostic (1.67e-1)" "unprognostic (5.42e-3)" "unprognostic (8.30e-2)" "unprognostic (1.27e-1)" "unprognostic (7.70e-2)" "unprognostic (3.73e-3)" "unprognostic (2.05e-1)" "unprognostic (7.00e-2)" "unprognostic (1.95e-2)" "unprognostic (1.94e-1)" "prognostic favorable (3.82e-7)" "unprognostic (2.84e-1)" "unprognostic (6.77e-2)" "unprognostic (2.01e-2)" "unprognostic (2.24e-3)" 42.6 36.4 70.3 4.9 111.3 0.2 22.0 92.2 88.0 11.4 13.5 9.2 4.5 6.4 5.8 17.2 17.3 21.7 96.2 68.6 82.1 29.0 11.8 121.5 2.4 93.9 103.9 35.6 10.5 71.7 16.2 9.5 98.6 55.5 7.4 35.7 72.4 24.7 203.9 12.2 7.2 10.3 90.8 107.8 10.0 9.5 88.8 7.3 41.1 277.5 3.3 25.3 7.6 135.4 2.4 26.7 40.3 2.7 0.1 0.1 3.9 33.9 17.1 33.2 16.7 4.1 10.5 0.1 106.2 90.5 1.0 18.8 23.1 15.6 37.2 0.2 3.1 0.1 180.0 0.2 33.4 0.0 0.2 0.6 44.5 0.0 10.3 146.9 3.3 0.0 0.0 0.1 9.6 14.9 0.1 0.1 2.8 5.8 2.9 0.0 49.2 0.7 27.9 181.0 37.9 76.8 102.5 40.2 0.6 32.2 3.0 0.2 0.1 0.4 38.6 9.3 26.0 0.1 0.1 0.3 2.6 0.0 144.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 70.3 111.3 92.2 88.0 68.6 82.1 93.9 103.9 98.6 90.8 88.8 135.4 101.4 650.7 211.5 205.3 0.8 39.0 50.9 5.9 33.6 32.1 80.0 32.3 242.4 28.6 90.1 95.6 37.5 16.4 0.4 4.8 21.5 40.3 107.7 31.0 10.6 77.6 9.6 0.0 434.8 14.0 45.7 51.8 16.3 44.3 5.1 13.8 128.5 11.5 13.0 0.0 551.3 11.7 6.1 13.3 30.9 29.0 1.8 5.2 14.2 121.8 19.5 82.6 0.0 64.8 1102.9 5.5 9.3 7.5 0.3 103.3 4.4 10.6 75.7 69.7 0.0 37.5 12.9 5.0 15.6 25.2 30.5 46.1 2.8 67.9 5.5 52.8 LMO7 "FBX20, FBXO20, KIAA0858" ENSG00000136153 "LIM domain 7" Q8WWI1 13 75620434-75859870 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 248.8" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 1682.7;Urothelial cells: 435.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 177 "amygdala: 12.6;basal ganglia: 19.9;cerebral cortex: 25.6;hippocampal formation: 14.9;white matter: 15.4" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 13.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 343.4;fHDF/TERT166: 568.2;LHCN-M2: 525.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "amygdala: 20.8;basal ganglia: 32.8;cerebral cortex: 26.6;hippocampal formation: 33.8" "HPA020923, HPA050184" Enhanced Supported "Actin filaments,Cytosol" NA NA 8200 "Cluster 32: T-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments" Cytosol "HPA020923: AB_1852963, HPA050184: AB_2681045" "unprognostic (2.07e-1)" "unprognostic (1.97e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (5.12e-4)" "unprognostic (1.75e-2)" "unprognostic (1.44e-1)" "unprognostic (1.57e-2)" "unprognostic (1.97e-1)" "unprognostic (1.52e-2)" "unprognostic (3.42e-2)" "prognostic unfavorable (3.51e-4)" "unprognostic (2.14e-1)" "prognostic favorable (7.75e-12)" "unprognostic (2.49e-1)" "unprognostic (2.82e-1)" "unprognostic (1.08e-1)" "unprognostic (8.33e-2)" 4.4 5.3 12.6 10.6 19.9 4.1 9.3 0.0 25.6 12.8 4.8 47.4 66.3 5.7 12.1 153.7 14.5 43.3 248.8 14.9 0.0 44.1 61.9 178.7 11.0 0.0 0.0 18.6 25.5 11.8 6.4 41.3 0.0 27.3 32.5 4.8 32.4 15.1 143.5 21.1 79.7 7.9 0.0 5.0 62.7 18.2 0.0 56.8 53.5 99.5 37.1 24.5 38.4 15.4 77.8 43.6 1.7 1.3 86.5 61.4 14.9 343.4 168.3 85.4 91.6 107.4 97.8 6.6 25.7 568.2 21.2 73.5 18.9 16.6 97.8 105.4 4.5 47.8 229.2 102.2 25.0 15.3 24.0 42.0 31.1 37.0 42.3 207.9 36.2 14.7 1.7 0.5 525.9 30.4 11.6 6.4 2.2 119.6 65.0 7.2 159.5 1.6 36.0 18.1 5.4 11.6 62.2 10.8 13.8 8.6 14.0 11.3 55.6 208.7 38.7 25.4 84.9 22.6 18.4 27.8 61.6 17.0 97.0 4.5 0.2 2.7 0.6 0.5 0.9 1.1 3.2 1.0 0.4 2.3 13.6 8.6 0.1 0.6 0.4 1.1 1.4 2.6 12.6 19.9 0.0 25.6 14.9 0.0 0.0 0.0 0.0 0.0 0.0 15.4 1.5 1682.7 279.7 22.2 4.3 24.0 74.7 59.9 72.8 6.8 10.5 13.2 362.6 51.5 317.2 62.5 2.1 45.5 3.6 378.5 15.6 81.5 6.2 92.0 19.0 9.0 71.2 3.6 162.3 37.8 8.7 38.0 276.3 244.4 20.3 9.5 6.1 72.7 6.0 6.7 82.5 96.6 67.1 3.5 4.4 8.0 42.0 6.4 16.0 39.4 2.8 1.9 3.1 30.7 48.4 228.8 351.2 42.5 2.1 344.9 213.8 15.5 199.5 10.5 13.1 27.2 18.1 11.2 6.3 100.9 45.3 17.0 12.9 2.5 75.2 435.7 LMOD2 ENSG00000170807 "Leiomodin 2" Q6P5Q4 7 123655866-123664290 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 39 "heart muscle: 778.4;skeletal muscle: 933.7;tongue: 793.6" "Cell type enriched" "Detected in some" 26 "Cardiomyocytes: 1432.4" "Group enriched" "Detected in some" 20 "head and neck cancer: 3.5;prostate cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HSkMC: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA046370, HPA051039" Enhanced Uncertain "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Actin filaments, Cytosol" "HPA046370: , HPA051039: AB_2681321" "unprognostic (2.55e-1)" "unprognostic (1.14e-1)" "unprognostic (1.43e-1)" "unprognostic (2.38e-3)" "unprognostic (1.18e-1)" "unprognostic (5.50e-1)" "unprognostic (5.69e-2)" "unprognostic (6.98e-2)" "unprognostic (2.13e-2)" "unprognostic (1.43e-3)" "unprognostic (3.37e-2)" "unprognostic (1.51e-1)" "unprognostic (1.82e-3)" 0.2 0.1 0.0 0.0 0.0 0.6 0.5 0.1 0.5 0.0 0.2 0.1 0.0 0.0 0.0 21.2 0.0 0.1 778.4 0.2 0.0 0.0 0.2 0.3 0.3 0.0 0.1 0.1 0.2 0.0 0.1 0.8 0.0 10.2 0.0 0.1 10.0 0.0 933.7 0.4 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.2 793.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1432.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.4 0.5 0.4 9.4 0.0 0.0 0.1 0.0 0.1 27.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.9 7.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 LPIN2 KIAA0249 ENSG00000101577 "Lipin 2" Q92539 18 2916994-3013144 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transcription, Transcription regulation" Hydrolase "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 165.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 154.4;Granulosa cells: 323.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 7 "granulocytes: 23.4;NK-cells: 12.5;T-cells: 12.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015223, HPA017857, HPA030550" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Cytosol "Plasma membrane, Actin filaments" "CAB015223: , HPA017857: AB_1852904, HPA030550: AB_2673519" "unprognostic (7.03e-2)" "unprognostic (1.05e-1)" "unprognostic (2.88e-1)" "unprognostic (1.51e-3)" "unprognostic (1.20e-1)" "prognostic favorable (8.01e-4)" "unprognostic (9.85e-3)" "unprognostic (1.89e-2)" "unprognostic (1.03e-2)" "unprognostic (3.44e-3)" "unprognostic (3.19e-1)" "unprognostic (1.94e-1)" "unprognostic (3.15e-3)" "unprognostic (4.66e-2)" "unprognostic (2.21e-1)" "unprognostic (2.49e-1)" "unprognostic (7.11e-2)" 9.7 9.3 17.9 21.2 19.9 19.8 9.8 14.6 17.4 9.7 16.6 13.9 62.8 9.8 6.7 10.0 9.5 25.7 7.2 16.1 24.2 26.4 165.8 21.2 24.3 22.7 22.0 13.2 16.4 13.5 10.9 15.7 24.2 9.0 12.5 10.7 7.4 8.0 2.7 3.6 39.9 9.6 15.6 20.3 28.1 22.0 28.8 18.9 12.1 3.0 19.2 9.9 6.0 14.3 8.7 12.0 17.1 6.6 31.7 27.4 10.5 17.4 22.8 18.9 16.9 16.7 7.1 5.4 10.8 30.2 30.2 0.2 13.8 6.3 13.2 11.2 2.7 13.3 10.0 19.4 27.2 11.2 17.0 27.4 4.6 18.5 17.2 28.2 23.4 14.8 12.8 3.5 28.2 7.2 15.0 12.0 5.7 13.7 13.1 26.7 14.0 23.2 17.6 20.0 14.4 10.2 18.4 9.1 6.8 10.7 0.0 18.0 31.2 25.3 28.7 31.7 14.6 5.0 7.9 12.3 22.1 12.2 8.1 8.7 2.4 7.8 11.8 1.5 12.1 1.0 9.2 7.2 1.0 1.7 9.1 6.3 23.4 12.5 0.8 1.5 9.2 3.2 17.9 19.9 14.6 17.4 16.1 24.2 22.7 22.0 24.2 15.6 28.8 14.3 17.7 67.3 44.0 55.2 20.4 5.6 9.8 8.5 5.7 35.7 12.1 11.2 11.2 154.4 23.9 38.6 14.6 25.2 41.9 45.3 17.6 11.8 3.3 48.2 33.3 18.9 14.9 138.1 26.3 19.0 11.3 25.4 103.0 64.4 12.6 323.0 19.2 131.1 23.1 116.1 65.6 36.8 16.2 26.8 8.9 11.0 22.7 31.1 8.8 79.6 31.2 16.7 59.8 37.7 21.0 22.2 21.6 31.2 16.1 21.2 92.4 54.9 17.1 16.7 6.6 16.6 20.1 26.5 73.0 0.6 2.0 49.5 58.9 20.3 14.0 14.1 LRCH1 "CHDC1, KIAA1016" ENSG00000136141 "Leucine rich repeats and calponin homology domain containing 1" Q9Y2L9 13 46553168-46753040 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 89.2;Inhibitory neurons: 117.6;Microglial cells: 183.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 37.1" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021536 Approved Approved "Nucleoli,Actin filaments,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Actin filaments, Cytosol" Nucleoli "HPA021536: AB_1853258" "unprognostic (7.13e-3)" "prognostic unfavorable (6.24e-4)" "unprognostic (3.59e-2)" "unprognostic (8.93e-2)" "unprognostic (7.50e-2)" "unprognostic (1.37e-1)" "unprognostic (5.16e-2)" "prognostic unfavorable (6.67e-4)" "unprognostic (2.16e-1)" "prognostic unfavorable (5.75e-4)" "unprognostic (1.39e-2)" "unprognostic (1.17e-1)" "prognostic favorable (1.04e-4)" "unprognostic (2.87e-1)" "unprognostic (1.22e-1)" "unprognostic (3.39e-1)" "unprognostic (1.98e-2)" 15.1 5.0 4.7 10.7 4.7 8.9 14.6 37.1 6.2 15.9 4.2 15.2 7.9 16.3 7.7 10.0 11.8 12.6 8.4 5.7 6.1 14.9 12.2 13.8 16.3 6.5 7.0 10.1 5.6 5.4 5.8 18.2 7.8 10.8 10.0 10.3 10.0 12.0 3.9 17.9 11.6 17.6 7.9 14.6 13.0 4.6 6.8 18.5 6.5 7.5 15.7 13.5 9.7 7.5 7.4 10.4 9.2 9.6 6.6 12.5 23.6 12.4 16.1 15.0 14.2 23.5 12.3 23.4 3.4 11.7 9.8 10.4 7.1 12.5 21.6 24.2 6.6 21.0 4.3 11.1 8.2 13.8 34.5 7.9 9.7 13.9 16.8 12.3 13.1 15.6 4.2 6.9 11.2 14.2 14.8 17.3 5.2 46.3 5.5 8.0 10.0 6.3 28.1 7.5 14.5 14.6 7.0 6.8 18.8 16.2 5.3 18.3 12.5 8.8 6.0 11.0 11.9 1.3 3.7 10.6 10.3 11.9 10.8 0.6 0.9 0.9 1.5 0.7 0.8 2.2 1.1 1.0 0.8 2.7 0.8 0.9 0.3 2.5 0.5 1.0 0.8 0.9 4.7 4.7 37.1 6.2 5.7 6.1 6.5 7.0 7.8 7.9 6.8 7.5 61.5 6.4 6.1 24.8 26.7 37.5 10.5 6.2 27.3 8.3 12.0 11.8 7.2 17.2 6.5 22.0 22.9 13.4 8.4 6.8 9.8 8.3 1.6 5.4 6.5 32.5 1.8 9.9 89.2 4.2 12.7 14.3 18.8 13.7 27.9 2.8 17.5 9.3 13.4 3.3 117.6 10.6 8.2 16.9 30.7 2.1 13.1 12.3 30.2 183.6 8.4 5.5 8.2 64.8 9.7 13.5 5.5 17.0 12.4 12.9 8.0 8.4 2.6 8.5 13.1 15.6 18.6 1.7 4.1 15.9 33.2 9.7 14.7 15.3 7.8 9.2 LRRFIP2 HUFI-2 ENSG00000093167 "LRR binding FLII interacting protein 2" Q9Y608 3 37052626-37183689 "Predicted intracellular proteins, Transcription factors" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 516.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035956, HPA042023" Uncertain Approved "Plasma membrane,Actin filaments" NA NA 150000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "HPA035956: AB_10671238, HPA042023: AB_2677802" "unprognostic (2.03e-3)" "prognostic favorable (6.31e-4)" "unprognostic (1.16e-2)" "unprognostic (7.90e-2)" "unprognostic (2.48e-1)" "unprognostic (2.97e-1)" "unprognostic (5.41e-2)" "unprognostic (1.82e-1)" "unprognostic (3.09e-2)" "unprognostic (2.56e-2)" "unprognostic (4.99e-3)" "unprognostic (1.98e-1)" "unprognostic (4.13e-3)" "unprognostic (2.62e-1)" "unprognostic (1.37e-1)" "unprognostic (4.84e-3)" "unprognostic (3.76e-2)" 23.4 24.0 43.7 20.1 46.9 44.3 22.3 43.6 49.0 46.0 33.6 38.3 35.4 31.8 19.7 52.6 25.8 22.0 75.8 38.8 44.4 24.0 48.5 27.0 18.1 43.4 42.0 27.4 19.2 33.3 18.6 20.8 44.8 41.0 34.2 36.0 28.5 24.3 97.9 37.0 36.2 31.5 41.0 45.0 26.5 71.8 46.4 18.8 27.5 45.3 23.2 24.2 40.9 60.9 56.6 30.8 34.9 27.7 45.5 69.3 30.5 149.9 148.2 82.6 94.3 29.0 25.3 22.2 24.0 145.4 40.8 28.8 25.8 74.2 134.3 49.7 20.2 39.8 44.0 28.6 64.8 31.9 23.3 31.1 52.1 107.8 110.4 45.8 58.2 34.0 32.3 37.8 69.5 14.4 27.2 17.0 23.0 23.0 39.2 13.0 99.2 22.6 58.4 21.7 12.6 19.9 57.9 53.0 49.4 28.0 30.6 32.6 56.5 63.1 42.6 93.4 71.5 29.1 57.1 33.9 37.1 28.1 91.4 20.5 21.4 33.8 8.8 14.9 11.3 9.7 9.3 9.5 14.1 8.5 6.8 8.3 19.2 16.9 26.9 7.9 13.0 11.7 43.7 46.9 43.6 49.0 38.8 44.4 43.4 42.0 44.8 41.0 46.4 60.9 47.8 28.9 36.5 98.6 29.1 136.1 143.0 41.3 113.8 36.3 64.7 53.2 123.1 38.6 53.7 23.9 29.2 29.2 28.7 117.2 64.6 89.8 516.2 78.9 44.0 59.9 54.0 60.0 169.8 94.3 46.1 57.4 37.8 127.3 52.6 29.4 56.7 58.8 24.9 122.8 197.7 45.6 28.5 35.6 128.3 330.7 42.3 48.2 74.7 62.8 67.7 51.9 30.9 130.7 309.0 109.9 90.1 57.6 45.8 325.6 125.8 46.1 36.2 51.9 39.5 32.4 72.8 159.9 73.4 139.3 170.5 39.3 34.1 90.0 66.0 303.2 LSM6 YDR378C ENSG00000164167 "LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated" P62312 4 146175703-146200000 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, rRNA processing, tRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045079 Approved Approved "Actin filaments" NA NA 30000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" "Actin filaments" "HPA045079: AB_10961320" "unprognostic (5.04e-3)" "unprognostic (4.91e-2)" "unprognostic (6.81e-2)" "unprognostic (1.67e-1)" "unprognostic (6.34e-2)" "unprognostic (3.72e-2)" "unprognostic (6.57e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (3.88e-4)" "unprognostic (2.28e-2)" "unprognostic (4.36e-1)" "unprognostic (8.20e-2)" "prognostic unfavorable (6.65e-4)" "unprognostic (1.51e-1)" "unprognostic (2.93e-1)" "unprognostic (2.15e-1)" "unprognostic (3.08e-3)" 11.2 6.2 6.2 10.0 6.7 11.4 6.9 9.6 13.5 5.3 4.5 10.1 5.8 5.5 5.8 5.2 5.4 4.6 4.4 5.4 7.1 7.9 9.9 6.2 18.3 6.9 7.3 6.8 6.4 3.9 4.3 9.1 6.8 7.4 7.6 8.3 6.8 4.5 4.3 4.8 8.2 4.9 6.9 10.4 8.9 7.5 6.9 12.5 4.2 5.7 14.2 8.5 4.4 6.6 21.1 11.1 28.0 11.3 9.4 9.7 19.2 17.7 17.8 17.2 18.9 12.1 23.7 27.9 6.3 10.3 16.3 8.8 22.7 10.8 27.5 35.1 15.7 18.4 8.9 32.2 16.0 50.1 16.1 7.0 15.9 17.2 7.8 10.5 16.6 19.7 25.4 31.0 13.7 17.5 56.4 37.0 21.7 21.9 14.3 29.9 14.8 14.3 13.4 23.2 23.8 11.3 9.7 12.6 22.0 15.3 9.8 37.1 12.2 16.2 17.9 11.8 29.9 17.7 23.5 32.9 20.2 16.0 18.6 3.5 27.4 18.4 18.2 43.9 24.1 32.3 23.8 21.6 26.6 33.3 26.6 24.1 16.2 26.8 59.6 21.3 28.3 30.8 6.2 6.7 9.6 13.5 5.4 7.1 6.9 7.3 6.8 6.9 6.9 6.6 143.3 22.4 34.1 11.8 86.7 69.3 91.2 141.8 56.9 22.5 55.3 88.0 25.1 51.5 55.9 27.6 2.1 132.7 53.5 38.2 68.4 67.2 3.6 53.4 44.9 68.7 23.4 82.6 12.3 67.1 183.4 65.6 30.1 33.1 56.4 52.1 54.7 65.8 124.9 18.5 13.3 66.2 61.1 96.2 98.0 13.8 76.1 98.2 51.6 7.5 171.2 33.7 74.2 16.6 13.1 53.1 83.6 57.9 60.6 162.8 92.7 111.5 64.3 25.0 32.9 47.5 82.2 107.3 196.2 78.0 71.7 73.7 77.1 71.6 85.5 99.8 LUZP1 LUZP ENSG00000169641 "Leucine zipper protein 1" Q86V48 1 23084023-23177808 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 349.1;Early spermatids: 291.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 39.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "TIME: 127.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028506, HPA028542" Enhanced Approved "Actin filaments" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments" "HPA028506: AB_10600083, HPA028542: AB_10601986" "unprognostic (3.04e-2)" "prognostic unfavorable (5.57e-4)" "unprognostic (7.35e-3)" "unprognostic (7.20e-2)" "unprognostic (3.96e-2)" "unprognostic (8.27e-2)" "unprognostic (8.46e-3)" "unprognostic (9.77e-3)" "unprognostic (7.34e-2)" "unprognostic (2.56e-3)" "unprognostic (1.19e-1)" "unprognostic (3.50e-1)" "prognostic favorable (1.46e-7)" "unprognostic (4.49e-1)" "unprognostic (2.09e-1)" "unprognostic (2.51e-1)" "unprognostic (1.33e-1)" 11.5 14.3 6.0 9.2 8.1 14.2 7.3 6.3 24.6 10.1 4.1 13.1 22.7 11.9 5.4 9.3 6.3 13.0 13.6 7.6 10.9 10.7 3.6 10.4 6.4 13.7 8.1 7.6 6.1 20.1 3.8 12.7 13.9 9.8 13.2 5.4 6.9 9.6 3.3 8.9 24.7 12.8 5.1 10.7 5.2 11.4 12.3 9.8 9.5 6.6 7.1 10.4 7.4 11.0 26.4 17.7 24.5 28.5 24.6 31.3 17.8 25.3 40.1 31.0 32.4 10.1 12.0 0.5 22.6 43.0 19.9 34.8 24.5 68.5 37.6 9.6 16.2 36.6 21.8 9.6 16.2 18.5 22.5 27.7 26.4 45.6 35.6 25.6 70.6 10.0 13.6 2.0 25.2 7.0 12.6 7.9 20.8 8.1 18.9 18.9 36.7 3.1 14.0 17.1 4.5 11.6 60.4 16.8 20.3 48.9 9.6 9.6 127.0 36.2 27.2 27.2 25.4 3.0 7.8 9.8 15.9 29.8 31.8 39.8 7.6 8.4 11.5 5.4 13.1 3.2 8.7 7.5 7.6 5.8 6.9 6.9 4.1 7.1 10.9 15.8 5.1 3.3 6.0 8.1 6.3 24.6 7.6 10.9 13.7 8.1 13.9 5.1 12.3 11.0 103.5 9.6 14.1 58.1 17.1 135.2 349.1 64.7 117.8 23.7 31.3 41.7 54.7 27.1 33.7 20.2 2.1 25.6 34.1 100.3 15.6 58.6 291.4 35.6 83.0 138.2 21.5 9.5 113.2 30.6 53.7 49.4 14.3 54.1 22.8 21.9 68.6 11.5 27.3 21.9 111.3 55.8 61.1 18.0 77.9 52.9 36.4 36.4 33.8 65.6 83.7 17.4 33.0 38.2 7.2 75.9 54.0 43.6 19.5 83.5 117.3 23.3 24.0 8.4 32.9 43.7 67.5 84.6 85.9 72.9 70.8 24.8 46.3 38.4 54.9 183.0 LYSMD4 FLJ33008 ENSG00000183060 "LysM domain containing 4" Q5XG99 15 99715697-99733561 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029152, HPA059824" Approved Approved "Actin filaments,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 62: Horizontal cells - Visual perception" Cytosol "Actin filaments" "HPA029152: AB_10602033, HPA059824: AB_2684135" "unprognostic (2.43e-3)" "unprognostic (1.30e-2)" "unprognostic (1.53e-1)" "unprognostic (2.81e-1)" "unprognostic (4.07e-3)" "unprognostic (3.80e-2)" "unprognostic (1.53e-3)" "unprognostic (3.75e-1)" "unprognostic (1.37e-1)" "unprognostic (1.88e-1)" "unprognostic (6.35e-3)" "unprognostic (9.77e-2)" "unprognostic (1.02e-2)" "unprognostic (2.06e-1)" "unprognostic (9.23e-2)" "unprognostic (3.29e-2)" "unprognostic (3.30e-1)" 7.1 5.5 6.3 1.7 6.8 3.1 6.7 6.3 7.1 8.4 6.2 9.7 4.8 9.4 3.4 11.1 8.1 1.5 20.2 6.4 6.0 11.8 11.8 7.6 2.3 5.9 6.4 8.9 8.0 5.7 7.1 2.8 6.2 9.5 3.2 5.2 9.5 4.2 10.3 16.7 7.9 3.8 5.9 8.0 7.8 7.7 7.0 3.9 5.0 5.9 3.8 7.9 9.4 6.8 3.5 3.3 6.5 3.8 7.1 6.4 3.9 3.9 2.7 3.3 4.8 8.2 3.0 3.8 2.3 3.6 5.8 10.1 5.1 6.3 3.8 0.8 9.2 2.5 7.2 5.7 4.1 1.8 4.6 3.7 9.2 3.0 3.6 2.0 4.5 10.9 6.2 4.8 2.2 4.1 4.8 5.1 4.3 9.7 3.7 3.4 4.6 1.9 5.9 9.0 3.7 3.3 7.2 2.2 3.9 8.3 1.5 3.5 5.8 2.7 7.3 3.7 1.7 6.3 9.1 3.1 3.5 4.5 2.9 0.0 1.3 5.3 2.1 1.9 1.7 1.0 3.0 2.6 0.6 1.7 3.5 1.6 0.4 0.7 2.7 3.0 3.2 2.4 6.3 6.8 6.3 7.1 6.4 6.0 5.9 6.4 6.2 5.9 7.0 6.8 7.0 6.4 3.3 4.6 2.5 8.7 8.1 4.6 8.0 8.0 3.5 6.3 12.8 7.2 3.9 3.7 10.4 2.6 4.9 4.4 1.9 4.1 7.3 1.3 3.0 4.8 3.0 6.1 9.8 9.7 2.0 6.8 3.6 1.7 0.0 2.9 3.9 3.4 4.3 10.1 11.4 6.2 6.1 2.2 3.7 8.1 5.3 3.9 1.8 8.4 8.1 11.6 3.1 6.0 7.4 7.2 3.0 6.8 3.9 2.1 3.9 5.3 2.5 10.0 13.1 3.9 5.7 12.7 11.3 8.1 9.1 1.4 2.9 2.2 2.6 3.5 LYZ ENSG00000090382 Lysozyme P61626 12 69348381-69354234 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase" "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 10588.1;salivary gland: 21115.5;stomach 1: 8941.1" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 3106.1;Kupffer cells: 2841.2;Langerhans cells: 4859.1;Macrophages: 4870.7;monocytes: 7063.0;Pancreatic endocrine cells: 3152.5" "Cancer enhanced" "Detected in all" "stomach cancer: 976.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 25266.2;myeloid DC: 14438.7" "Group enriched" "Detected in all" 20 "dendritic cells: 14438.7;monocytes: 25266.2" "Cell line enriched" "Detected in many" 13 "OE19: 12130.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000055, HPA048284, HPA066182" Enhanced Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" NA NA 1500000000 1500000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus, Actin filaments" Nucleoplasm "CAB000055: AB_2341230, HPA048284: AB_2680339, HPA066182: AB_2732741" "unprognostic (8.52e-2)" "unprognostic (6.12e-3)" "unprognostic (2.83e-1)" "unprognostic (7.29e-2)" "unprognostic (7.91e-2)" "prognostic favorable (7.45e-4)" "unprognostic (1.21e-1)" "unprognostic (7.40e-2)" "unprognostic (1.41e-1)" "unprognostic (2.08e-2)" "unprognostic (1.44e-1)" "unprognostic (3.13e-1)" "unprognostic (2.50e-1)" "unprognostic (2.37e-1)" "unprognostic (3.65e-2)" "unprognostic (5.78e-2)" "unprognostic (3.62e-2)" 95.8 27.8 3.5 802.1 4.0 10588.1 128.2 3.7 18.5 156.2 11.4 309.0 3605.0 65.7 4.2 106.3 33.9 1054.6 34.8 2.6 4.3 32.4 138.0 1355.2 739.7 8.0 7.3 20.4 63.1 13.8 7.2 91.3 12.2 40.2 273.8 4.4 21115.5 21.8 34.0 58.7 1322.2 123.9 5.4 621.0 8941.1 21.8 10.9 321.8 27.8 36.4 652.8 428.5 16.2 11.7 0.6 0.1 0.0 0.2 0.0 0.0 4.8 0.0 0.0 0.0 0.3 9.5 6.5 4.2 1.5 0.0 3.6 1.2 0.0 0.0 0.2 1.2 0.1 62.4 1.0 960.4 0.0 110.6 50.5 0.0 0.1 0.0 0.0 0.2 0.0 0.3 7.7 0.3 0.0 0.2 2.6 109.5 2.3 12130.8 0.2 1.6 1.4 16.7 0.3 0.5 0.8 3.6 0.5 0.1 0.5 0.7 0.0 489.0 0.6 0.0 2.6 2.3 0.9 2.6 1.1 1.2 0.1 518.5 0.0 443.4 25266.2 298.2 32.6 4798.4 52.3 100.5 20.1 22.7 14438.7 20.8 20.0 17.8 1007.7 108.1 880.1 301.2 31.1 25392.1 3.5 4.0 3.7 18.5 2.6 4.3 8.0 7.3 12.2 5.4 10.9 11.7 24.0 86.6 285.8 0.0 80.8 57.2 1.7 1.2 1.2 0.3 1205.7 32.3 0.2 734.9 51.1 27.6 0.0 5.6 39.6 32.1 0.0 55.1 1.9 2.6 1.9 25.1 12.5 264.6 0.2 547.3 9.4 26.8 3106.1 2.9 123.6 0.5 29.6 25.4 887.1 0.0 0.2 112.4 0.0 2841.2 4859.1 17.4 4.1 4870.7 53.4 0.0 7063.0 0.1 176.1 0.0 0.3 3152.5 600.5 2.2 9.0 2.7 41.8 6.6 33.8 1.0 39.5 7.4 9.9 0.7 3.9 1.5 38.2 8.5 50.6 0.3 111.4 38.3 MACF1 "ABP620, ACF7, FLJ45612, FLJ46776, KIAA0465, KIAA1251, MACF" ENSG00000127603 "Microtubule actin crosslinking factor 1" Q9UPN3 1 39081316-39487177 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" Actin-binding "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 1079.0;Cone photoreceptor cells: 779.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013713, HPA068064, HPA068103" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments" NA NA 25000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cell Junctions, Actin filaments" "HPA013713: AB_10600821, HPA068064: AB_2685946, HPA068103: AB_2685953" "unprognostic (2.71e-1)" "unprognostic (3.14e-2)" "unprognostic (5.18e-2)" "unprognostic (1.02e-2)" "unprognostic (9.00e-2)" "unprognostic (6.19e-3)" "unprognostic (1.32e-1)" "unprognostic (7.40e-3)" "unprognostic (5.45e-2)" "unprognostic (1.23e-1)" "unprognostic (1.34e-1)" "unprognostic (3.98e-1)" "prognostic favorable (2.77e-5)" "unprognostic (1.07e-1)" "unprognostic (1.81e-1)" "unprognostic (8.57e-2)" "unprognostic (4.22e-2)" 69.1 62.5 172.0 27.7 197.5 36.2 54.6 174.6 181.6 65.9 119.1 148.6 18.6 130.3 48.7 46.4 92.0 46.4 127.0 159.7 166.1 85.7 63.8 183.6 35.9 190.2 179.0 92.6 51.2 96.9 69.3 34.6 182.9 68.2 25.1 121.2 57.7 41.6 73.0 121.0 62.6 54.2 155.6 84.9 71.3 50.2 193.2 39.3 73.3 55.2 22.8 80.3 62.7 185.3 48.1 54.9 66.7 29.3 53.8 47.3 29.8 62.2 79.4 38.0 33.7 34.3 56.5 24.4 64.6 84.0 62.1 30.6 12.5 45.7 51.2 43.5 33.1 34.0 43.4 56.5 66.0 30.8 15.9 37.0 46.5 105.1 54.3 83.5 104.7 52.0 63.2 25.7 137.0 16.0 23.3 52.7 95.8 20.0 31.7 38.5 89.6 4.5 206.0 50.8 38.2 38.6 24.9 17.2 62.5 76.3 7.5 37.9 115.1 61.6 48.5 28.8 101.9 19.4 19.7 28.8 101.0 32.6 55.2 7.5 1.3 3.8 12.2 2.7 5.9 2.2 5.8 7.8 1.8 3.8 4.7 6.1 1.3 6.5 2.9 2.5 3.0 2.0 172.0 197.5 174.6 181.6 159.7 166.1 190.2 179.0 182.9 155.6 193.2 185.3 135.3 150.6 128.2 1079.0 68.7 154.4 74.9 43.0 60.3 387.7 52.5 50.9 246.1 61.5 70.7 80.9 779.8 52.6 120.5 35.4 0.0 113.3 9.6 140.6 124.4 164.3 36.1 57.6 320.6 114.6 62.1 108.2 65.2 180.1 77.7 194.3 132.1 47.9 52.1 117.8 367.5 27.2 22.4 59.7 46.3 11.8 43.8 74.8 71.2 342.9 59.0 107.8 158.6 494.6 410.7 193.5 17.7 112.5 81.0 89.7 22.5 20.6 71.3 398.5 105.2 95.5 136.7 62.6 33.7 43.5 191.5 69.9 131.2 76.5 19.7 78.8 MAGEF1 ENSG00000177383 "MAGE family member F1" Q9HAY2 3 184710364-184712064 "Predicted intracellular proteins" "Ubl conjugation pathway" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 146.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046899, HPA054190" Uncertain Approved "Actin filaments" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 35: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "Actin filaments" "HPA046899: AB_2679859, HPA054190: AB_2682411" "unprognostic (7.36e-3)" "unprognostic (3.79e-2)" "unprognostic (3.81e-2)" "unprognostic (1.10e-2)" "unprognostic (4.27e-2)" "unprognostic (4.46e-3)" "unprognostic (2.34e-3)" "unprognostic (1.37e-1)" "unprognostic (2.42e-1)" "unprognostic (2.80e-3)" "unprognostic (1.82e-1)" "unprognostic (8.51e-3)" "prognostic favorable (7.59e-4)" "unprognostic (7.65e-2)" "unprognostic (8.97e-2)" "unprognostic (3.15e-3)" "unprognostic (1.19e-1)" 16.8 26.9 28.9 16.4 29.3 2.7 24.0 29.6 33.4 33.7 31.3 28.2 17.4 32.4 35.9 20.7 26.1 15.5 26.2 29.1 37.7 36.3 25.4 20.3 21.3 29.0 29.8 27.4 29.3 35.5 56.3 23.1 29.2 30.3 17.1 27.0 25.9 26.8 32.6 22.7 20.3 19.1 29.7 19.1 27.0 12.3 31.8 21.7 29.7 21.7 17.6 27.3 21.7 27.9 86.3 22.3 89.8 56.1 32.0 12.9 61.8 32.1 34.9 53.2 53.3 54.8 31.3 59.1 65.2 29.2 88.1 60.0 46.2 27.7 49.0 96.2 65.1 17.3 32.9 77.4 31.5 27.4 27.4 29.7 34.4 33.9 10.7 25.4 13.0 19.3 30.3 40.0 31.5 108.8 10.4 60.8 56.9 54.6 38.4 29.9 72.6 18.4 39.5 56.4 99.0 94.6 49.5 83.1 77.4 50.0 132.4 10.1 9.1 35.0 61.6 41.1 62.9 82.9 65.6 78.7 27.6 9.8 46.3 0.1 1.4 2.5 1.6 0.3 0.6 2.8 2.2 1.8 5.7 4.7 6.1 3.1 0.2 1.2 0.2 0.4 2.3 0.9 28.9 29.3 29.6 33.4 29.1 37.7 29.0 29.8 29.2 29.7 31.8 27.9 6.5 32.1 25.8 10.4 22.1 18.7 52.7 56.9 30.1 60.3 37.5 33.7 19.2 48.6 33.0 42.3 10.4 103.2 6.0 9.2 146.8 54.3 1.2 27.0 22.3 16.0 49.3 13.2 14.6 41.3 56.4 37.3 27.5 19.0 5.7 36.1 20.3 26.2 68.6 63.9 15.1 46.1 71.2 8.1 36.3 3.9 55.3 10.1 24.9 6.5 32.3 67.3 20.6 13.6 12.6 30.0 22.4 57.2 26.5 44.3 11.2 64.8 30.1 49.2 32.9 30.7 33.4 21.3 8.9 29.6 13.8 60.5 11.4 56.8 32.5 72.3 MAP3K10 "MEKK10, MLK2, MST" ENSG00000130758 "Mitogen-activated protein kinase kinase kinase 10" Q02779 19 40191426-40215575 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 46.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 18.9;Horizontal cells: 23.5" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 8 "amygdala: 22.8;basal ganglia: 17.5;cerebral cortex: 46.2;hippocampal formation: 37.7;white matter: 11.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007039 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Actin filaments, Cytosol" "HPA007039: AB_1079357" "unprognostic (2.09e-1)" "unprognostic (3.77e-2)" "unprognostic (1.42e-3)" "unprognostic (2.03e-2)" "unprognostic (2.04e-1)" "prognostic favorable (8.69e-4)" "unprognostic (4.50e-3)" "unprognostic (1.80e-1)" "unprognostic (3.94e-2)" "unprognostic (6.13e-2)" "unprognostic (1.34e-3)" "unprognostic (4.62e-3)" "unprognostic (6.88e-2)" "unprognostic (1.53e-2)" "unprognostic (1.51e-2)" "unprognostic (4.77e-3)" "prognostic favorable (2.13e-4)" 6.9 8.3 22.8 2.3 17.5 1.9 6.5 0.0 46.2 7.7 0.0 8.6 2.0 7.9 0.3 5.3 6.6 1.8 10.7 37.7 0.1 7.4 5.2 6.7 2.3 3.2 0.6 7.3 6.9 3.3 14.3 1.6 0.0 8.1 0.6 1.4 5.9 2.0 16.8 7.1 6.3 1.8 0.0 8.1 7.1 11.1 2.4 1.8 6.9 4.3 0.9 7.2 6.6 11.6 6.3 7.2 2.2 5.2 2.0 1.2 6.2 4.3 2.0 1.9 1.9 1.7 1.7 5.7 4.4 1.4 4.6 1.9 0.8 2.2 0.2 10.9 6.8 1.4 3.3 1.7 3.8 1.2 3.4 1.1 5.0 2.0 1.4 2.0 1.7 7.6 5.5 9.1 0.5 3.7 4.5 2.2 2.6 2.0 4.7 5.8 2.3 3.4 1.7 3.8 7.4 10.7 4.9 1.7 10.0 1.3 2.4 2.2 2.9 4.9 4.8 7.3 8.3 12.7 7.7 2.6 5.7 2.3 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.8 17.5 0.0 46.2 37.7 0.1 3.2 0.6 0.0 0.0 2.4 11.6 5.6 0.0 0.0 6.5 4.2 1.5 1.8 1.1 1.2 14.9 2.9 2.4 2.8 5.7 0.5 7.3 8.4 0.9 3.3 2.4 0.0 2.5 2.8 2.4 3.6 3.6 4.2 5.3 18.9 4.3 0.8 2.6 5.6 3.8 0.0 10.3 3.9 3.2 2.5 23.5 15.9 1.7 0.0 1.6 2.9 7.6 3.1 2.7 1.8 9.4 2.5 5.7 4.1 9.0 12.4 3.7 2.9 4.9 1.5 2.5 1.7 3.1 0.6 7.7 6.6 4.5 4.0 4.1 1.8 1.8 2.7 1.4 4.4 3.2 2.4 2.0 MAP3K6 "ASK2, MAPKKK6, MEKK6" ENSG00000142733 "Mitogen-activated protein kinase kinase kinase 6" O95382 1 27354067-27366961 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 45.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA051192 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Plasma membrane, Actin filaments, Cytosol" "HPA051192: AB_2681380" "unprognostic (1.19e-2)" "unprognostic (2.77e-3)" "unprognostic (2.62e-2)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.13e-4)" "prognostic favorable (7.26e-4)" "prognostic unfavorable (8.76e-4)" "unprognostic (9.10e-2)" "unprognostic (2.79e-1)" "unprognostic (6.91e-2)" "unprognostic (6.56e-2)" "unprognostic (1.25e-1)" "unprognostic (4.65e-3)" "unprognostic (4.95e-2)" "unprognostic (2.79e-1)" "unprognostic (7.07e-3)" "unprognostic (1.50e-1)" 42.9 17.8 17.2 5.5 17.0 0.6 42.6 17.4 20.7 50.2 16.8 25.4 1.8 30.9 4.1 70.0 38.8 4.7 61.8 16.6 17.4 37.3 10.4 54.2 4.7 18.4 17.5 15.6 15.2 5.2 18.0 5.1 17.6 41.3 4.5 1.4 30.3 7.3 15.2 65.7 17.7 12.1 17.3 22.3 23.6 8.3 18.4 2.8 30.3 11.3 7.9 39.8 53.4 16.6 7.2 7.2 6.9 4.4 9.9 12.5 1.4 9.0 5.3 7.2 4.4 2.0 9.4 0.1 8.4 16.4 3.2 10.1 2.0 6.4 3.6 6.5 7.1 0.3 16.0 4.7 2.7 0.5 0.4 10.2 17.6 7.8 2.3 8.8 4.0 0.7 2.0 2.7 10.2 25.1 0.2 9.0 2.2 8.7 8.1 2.3 3.2 1.7 12.9 9.1 2.0 3.0 8.5 7.1 6.3 3.1 4.4 5.0 11.6 13.2 7.2 16.6 5.2 3.5 4.1 0.0 12.1 5.8 4.3 0.9 0.6 3.3 2.8 2.0 3.7 1.5 2.5 3.1 1.3 2.0 1.8 1.6 1.2 0.7 4.5 0.0 3.0 1.2 17.2 17.0 17.4 20.7 16.6 17.4 18.4 17.5 17.6 17.3 18.4 16.6 45.8 19.2 17.8 6.2 3.9 12.5 11.9 8.8 17.1 1.1 8.1 8.9 12.2 5.7 10.3 3.7 0.0 1.2 4.3 8.4 3.9 2.8 0.4 2.3 6.0 27.7 0.0 0.8 1.5 4.4 2.5 10.3 8.6 5.2 2.5 1.2 28.9 0.9 2.8 5.0 1.7 6.1 4.1 8.5 7.1 1.2 16.1 6.4 5.4 5.6 9.3 5.4 8.2 0.0 0.2 12.8 1.9 15.1 3.1 9.5 1.1 1.7 6.2 0.8 6.6 10.8 11.1 13.5 7.7 14.7 14.8 0.1 8.2 0.3 8.8 14.9 MARCKSL1 "F52, MacMARCKS, MLP, MLP1" ENSG00000175130 "MARCKS like 1" P49006 1 32333839-32336233 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 712.7" "Cell type enhanced" "Detected in many" "monocytes: 941.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 8 "eosinophil: 252.7" "Lineage enriched" "Detected in all" 8 "granulocytes: 252.7" "Cell line enhanced" "Detected in many" "AF22: 1016.3;NTERA-2: 984.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020787, HPA030528" Enhanced Supported "Nucleoplasm,Actin filaments,Cytosol" NA Yes 170000 "Cluster 52: Eosinophils - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 5: NTERA-2 - Transcription" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "Nucleoplasm, Actin filaments" "CAB020787: , HPA030528: AB_2673514" "unprognostic (8.08e-2)" "unprognostic (1.28e-1)" "unprognostic (1.11e-1)" "unprognostic (1.04e-2)" "unprognostic (1.38e-1)" "unprognostic (3.16e-3)" "prognostic unfavorable (1.78e-6)" "unprognostic (3.65e-1)" "unprognostic (1.72e-1)" "unprognostic (8.41e-3)" "unprognostic (2.91e-1)" "unprognostic (1.76e-2)" "prognostic unfavorable (1.20e-4)" "unprognostic (1.50e-1)" "unprognostic (8.16e-3)" "unprognostic (1.08e-1)" "unprognostic (3.22e-2)" 63.4 59.9 363.5 82.1 510.3 50.1 102.9 540.1 438.2 81.2 206.4 108.1 61.8 93.4 155.8 15.1 72.2 97.2 55.0 343.0 408.0 51.1 38.7 40.0 176.0 631.5 504.7 358.0 23.7 6.5 22.9 42.9 534.9 84.7 116.5 37.9 75.9 49.9 8.7 28.3 56.1 42.7 467.9 63.1 132.8 139.2 466.4 166.0 110.3 11.0 199.5 77.8 27.1 712.7 82.9 73.3 1016.3 418.6 22.5 8.3 181.0 34.0 21.2 99.9 66.0 176.0 59.9 185.7 124.4 23.2 0.3 43.0 333.1 3.8 73.3 4.5 246.5 10.0 27.0 392.4 68.7 48.8 0.9 114.8 13.7 75.0 2.1 154.2 295.0 312.6 291.5 2.2 135.7 197.5 613.5 205.9 984.3 267.4 168.1 754.8 109.4 87.7 152.1 163.1 629.0 597.8 178.8 194.2 587.8 411.9 135.4 85.8 87.8 41.8 241.3 3.9 66.1 27.8 2.3 489.8 4.7 73.6 225.7 3.1 4.0 252.7 3.8 23.1 1.4 20.0 7.4 4.9 6.6 27.7 15.3 6.4 18.2 1.1 30.3 9.0 4.8 4.9 363.5 510.3 540.1 438.2 343.0 408.0 631.5 504.7 534.9 467.9 466.4 712.7 242.5 0.0 1.3 27.1 191.1 93.7 114.7 43.5 40.5 27.7 465.7 385.8 8.5 178.7 68.8 60.7 6.2 16.1 110.1 194.1 82.2 389.7 37.4 68.7 190.3 326.9 746.2 74.4 4.2 307.2 116.4 124.3 246.2 115.2 22.3 378.6 462.3 5.3 21.2 10.1 21.9 514.2 236.0 61.0 365.3 66.7 613.3 82.0 300.6 9.4 941.4 464.3 46.4 93.0 428.3 751.6 292.8 641.3 39.5 418.8 30.2 9.8 15.6 14.8 131.5 40.3 210.0 14.8 102.7 22.5 83.1 13.4 89.8 172.0 447.1 586.9 MCMDC2 "C8orf45, FLJ25692" ENSG00000178460 "Minichromosome maintenance domain containing 2" Q4G0Z9 8 66870749-66922048 "Predicted intracellular proteins" "DNA damage, DNA repair, Meiosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 11.9" "Group enriched" "Detected in many" 4 "Early spermatids: 50.7;Spermatocytes: 65.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SK-MEL-30: 12.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA026522 Approved "Actin filaments" NA NA "Cluster 30: Non-specific - Translation" "Cluster 23: Testis - Cell cycle regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Actin filaments" "HPA026522: AB_10603453" "unprognostic (6.97e-2)" "unprognostic (1.08e-1)" "unprognostic (1.39e-1)" "unprognostic (2.85e-2)" "unprognostic (6.16e-3)" "unprognostic (5.54e-2)" "unprognostic (2.38e-2)" "unprognostic (3.03e-1)" "unprognostic (1.42e-1)" "unprognostic (9.46e-2)" "unprognostic (9.89e-2)" "unprognostic (4.04e-1)" "unprognostic (6.79e-3)" "unprognostic (7.87e-2)" "unprognostic (3.06e-2)" "unprognostic (8.49e-2)" "unprognostic (2.31e-5)" 1.1 1.8 0.5 1.3 1.1 4.1 0.7 2.0 0.9 0.4 0.0 0.7 1.4 1.2 0.9 1.6 1.0 1.1 2.5 0.4 0.7 1.0 0.6 0.8 2.8 1.0 0.8 3.0 1.5 1.1 0.9 0.5 0.9 0.9 0.7 4.4 1.4 0.3 5.9 2.2 1.4 0.1 0.7 1.2 1.0 11.9 0.7 0.2 1.4 1.4 0.2 0.7 0.3 1.9 2.7 5.6 2.8 3.4 0.4 1.3 1.5 2.5 0.4 0.2 0.2 4.8 3.5 4.1 1.0 0.2 1.5 2.3 0.0 0.1 0.8 2.1 6.9 5.1 8.9 5.8 0.6 2.3 2.7 0.9 0.8 0.1 0.0 4.1 0.2 3.9 3.2 3.8 1.1 5.3 5.8 7.2 3.5 4.5 5.1 2.0 1.0 1.8 0.5 4.1 1.9 3.5 0.8 1.0 12.3 1.6 3.5 6.0 1.2 1.9 2.7 3.2 3.1 3.1 1.8 3.9 2.1 4.8 2.0 0.9 0.5 0.2 0.9 0.4 1.2 1.0 1.4 1.1 1.1 1.0 1.6 1.4 0.2 1.3 0.3 1.2 1.1 0.5 0.5 1.1 2.0 0.9 0.4 0.7 1.0 0.8 0.9 0.7 0.7 1.9 0.4 0.0 0.5 12.4 0.7 0.4 0.5 0.4 1.2 2.0 1.8 1.3 2.7 0.0 0.4 1.8 6.2 1.2 0.2 0.4 0.0 0.2 50.7 4.9 0.9 0.7 0.0 0.0 6.2 0.2 0.6 0.5 2.6 0.6 0.0 0.7 0.4 0.0 0.5 1.7 5.1 0.8 0.0 1.6 0.3 12.4 1.8 0.4 1.8 0.0 0.0 2.0 1.0 6.0 12.0 0.1 0.3 0.7 0.2 0.2 0.2 0.8 3.6 2.4 0.0 1.0 0.6 65.7 11.1 1.3 1.0 0.0 0.7 1.2 1.2 0.6 METTL15 "FLJ33979, METT5D1" ENSG00000169519 "Methyltransferase like 15" A6NJ78 11 28108248-28527041 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 130.2;Oligodendrocyte precursor cells: 132.7;Oligodendrocytes: 146.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039885 Approved "Golgi apparatus,Plasma membrane,Actin filaments" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Golgi apparatus, Plasma membrane" "Actin filaments" "HPA039885: AB_2676725" "unprognostic (2.57e-1)" "unprognostic (2.64e-1)" "unprognostic (1.00e-2)" "unprognostic (3.21e-2)" "unprognostic (2.66e-2)" "unprognostic (1.83e-1)" "unprognostic (4.17e-2)" "unprognostic (1.95e-1)" "unprognostic (2.94e-2)" "unprognostic (7.93e-2)" "unprognostic (6.31e-3)" "unprognostic (2.28e-1)" "prognostic favorable (7.95e-5)" "unprognostic (7.77e-2)" "unprognostic (1.38e-1)" "unprognostic (6.58e-2)" "unprognostic (6.84e-3)" 4.3 8.1 4.8 4.1 4.5 2.3 6.2 5.5 5.4 6.1 6.1 7.0 5.1 5.0 5.7 4.6 5.7 4.5 7.7 4.9 5.4 7.7 9.3 4.3 5.3 4.9 4.8 5.9 4.4 7.0 4.2 5.1 5.2 6.3 6.9 7.0 4.5 5.6 8.7 5.1 5.1 4.5 4.5 4.3 5.4 3.3 5.2 5.2 7.6 11.2 5.3 4.4 3.3 6.2 8.8 9.2 9.3 7.1 11.3 18.0 6.5 10.6 8.1 10.6 10.9 6.3 5.9 20.2 6.2 8.8 6.7 7.3 12.3 10.9 20.2 12.5 10.8 6.4 6.5 7.3 12.6 12.1 5.6 10.2 16.0 5.9 15.1 11.5 10.3 6.7 13.7 8.9 12.6 6.0 8.4 7.4 7.2 9.2 6.8 4.5 20.2 7.4 15.8 5.0 8.2 6.7 8.8 7.8 12.7 8.9 15.4 7.4 7.8 9.6 7.4 12.3 9.4 6.0 7.6 11.7 13.5 12.0 10.6 2.1 1.4 3.7 2.2 1.0 2.7 3.6 2.6 2.9 1.7 1.8 2.8 3.6 0.6 4.4 1.2 1.8 3.1 1.5 4.8 4.5 5.5 5.4 4.9 5.4 4.9 4.8 5.2 4.5 5.2 6.2 16.5 12.8 24.3 130.2 21.3 44.0 38.1 37.1 23.9 13.6 21.6 15.0 14.3 14.3 20.3 11.0 18.8 11.3 28.7 18.2 11.7 10.6 34.5 19.6 24.7 15.7 9.6 17.0 96.8 11.8 14.1 23.5 16.3 28.2 5.1 18.1 12.8 15.0 10.4 13.5 93.9 17.6 10.2 14.2 50.7 12.6 10.8 17.9 14.2 105.9 6.1 8.7 19.6 132.7 146.1 9.9 13.3 8.2 21.0 57.2 13.0 14.9 18.9 16.1 6.6 60.7 23.2 17.9 10.0 17.4 35.7 8.5 35.5 21.3 16.2 53.1 MPP4 DLG6 ENSG00000082126 "Membrane palmitoylated protein 4" Q96JB8 2 201644870-201698694 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 194 "retina: 286.2" "Group enriched" "Detected in some" 36 "Cone photoreceptor cells: 1586.7;Rod photoreceptor cells: 808.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBF TERT88: 22.2;hTEC/SVTERT24-B: 21.0;LHCN-M2: 85.8;TIME: 16.4;U-87 MG: 21.3" "Low region specificity" "Detected in single" "Region enhanced" "Detected in single" "cerebellum: 2.7" HPA057393 Supported "Actin filaments,Cytosol" No No "Cluster 79: Retina - Phototransduction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "Actin filaments" "HPA057393: AB_2732612" "unprognostic (1.42e-2)" "unprognostic (1.82e-2)" "unprognostic (2.55e-1)" "unprognostic (2.50e-2)" "unprognostic (2.22e-2)" "unprognostic (6.66e-2)" "unprognostic (1.09e-2)" "unprognostic (9.42e-2)" "unprognostic (1.19e-1)" "unprognostic (1.39e-1)" "unprognostic (1.19e-1)" "unprognostic (9.20e-2)" "unprognostic (3.33e-16)" "unprognostic (1.82e-2)" "unprognostic (8.23e-2)" "unprognostic (1.29e-1)" "unprognostic (3.34e-2)" 0.1 0.5 0.3 0.1 0.3 0.0 0.1 1.3 0.4 0.7 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.4 0.2 0.1 0.1 0.1 0.0 0.6 0.1 0.1 0.0 0.0 0.3 0.1 0.2 0.1 0.0 286.2 0.0 0.1 0.1 0.8 0.0 0.0 0.1 1.4 0.0 0.5 0.1 0.0 0.1 0.1 0.0 0.1 0.5 0.3 0.0 0.0 0.0 0.0 0.1 6.6 0.0 11.2 2.7 6.6 6.7 0.0 0.0 0.0 0.0 2.6 1.0 0.0 0.0 0.8 22.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.7 0.0 21.0 0.1 3.2 12.3 0.1 0.0 0.0 85.8 0.0 0.0 0.0 0.6 0.0 2.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 16.4 8.4 2.6 2.0 7.8 0.0 0.0 0.0 21.3 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.3 0.4 0.4 0.2 0.6 0.1 0.2 0.1 0.1 0.3 0.7 3.2 8.6 0.3 0.0 0.4 0.0 0.2 0.0 20.0 0.4 0.0 0.2 1.5 6.2 1.8 1586.7 0.1 0.2 0.0 0.0 0.2 2.8 0.4 0.4 2.6 0.0 0.0 7.3 0.2 0.1 0.6 0.0 0.1 3.8 0.1 0.0 0.1 0.1 18.5 2.8 0.0 0.0 0.3 0.9 2.5 0.0 0.4 1.8 0.0 0.1 33.0 1.0 2.0 0.3 0.2 0.0 0.0 0.0 0.1 0.2 0.1 6.7 808.3 0.0 1.4 1.1 0.1 0.4 0.0 0.4 0.0 0.3 0.1 0.2 0.0 MPRIP "M-RIP, p116Rip, RHOIP3" ENSG00000133030 "Myosin phosphatase Rho interacting protein" Q6WCQ1 17 17042457-17217679 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 60.9" "Lineage enriched" "Detected in all" 6 "T-cells: 60.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022034, HPA022901" Enhanced Supported "Actin filaments,Cytosol" NA NA 29000 "Cluster 35: T-regs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 48: Smooth muscle cells - ECM organization" "Actin filaments" Cytosol "HPA022034: AB_1854093, HPA022901: AB_2297761" "unprognostic (1.92e-2)" "unprognostic (1.53e-3)" "unprognostic (5.81e-3)" "unprognostic (9.92e-3)" "unprognostic (1.01e-1)" "unprognostic (5.16e-2)" "unprognostic (4.19e-1)" "unprognostic (3.55e-2)" "unprognostic (5.18e-2)" "unprognostic (9.01e-3)" "unprognostic (1.55e-1)" "unprognostic (1.60e-1)" "unprognostic (6.56e-2)" "unprognostic (2.38e-1)" "unprognostic (1.19e-1)" "unprognostic (1.92e-1)" "unprognostic (5.04e-2)" 126.1 110.0 166.8 74.9 213.0 68.1 102.7 165.7 184.3 128.6 113.4 128.4 78.6 172.7 83.7 151.7 120.5 73.8 245.6 184.5 142.9 156.8 129.1 144.5 80.4 165.5 157.1 90.3 137.5 96.7 116.0 70.5 170.7 113.0 59.9 59.0 83.2 91.8 168.3 96.2 103.3 133.6 145.0 102.2 141.2 99.2 173.6 89.7 139.4 84.6 76.9 133.0 135.3 168.2 328.5 241.7 103.6 85.1 107.2 79.3 146.0 155.2 117.6 131.9 96.9 189.2 242.3 129.3 151.0 251.4 108.9 292.1 133.4 227.3 139.3 127.7 69.8 70.3 216.9 68.6 72.3 38.6 49.4 76.8 133.4 149.9 114.0 189.8 138.9 97.9 43.5 73.1 213.3 113.0 158.1 131.9 46.6 324.2 275.9 127.6 162.4 48.9 101.6 155.3 57.3 94.4 174.7 144.2 81.4 414.0 68.8 60.3 130.8 118.4 128.0 321.3 280.2 51.6 45.0 61.1 221.3 69.1 297.7 2.4 2.5 3.5 8.5 1.9 18.3 9.3 34.8 14.4 2.4 6.9 24.8 12.1 1.1 4.5 1.8 10.0 60.9 9.9 166.8 213.0 165.7 184.3 184.5 142.9 165.5 157.1 170.7 145.0 173.6 168.2 75.9 32.1 48.0 87.1 22.2 27.0 27.9 22.7 12.5 104.6 26.2 29.2 59.9 31.5 30.6 25.8 81.3 25.9 32.9 46.9 3.9 31.8 28.5 43.7 47.4 62.1 22.7 25.0 94.0 28.7 36.2 39.7 72.4 79.4 16.5 51.3 37.9 21.7 12.3 97.6 75.6 17.3 26.4 14.3 18.6 32.4 29.2 17.7 32.0 43.1 13.5 31.3 17.5 73.4 84.4 92.4 26.4 43.2 19.0 40.2 27.9 9.2 30.6 49.3 78.9 71.0 110.4 24.3 31.4 22.4 27.4 31.7 35.0 49.4 27.1 103.0 MRPS10 FLJ10567 ENSG00000048544 "Mitochondrial ribosomal protein S10" P82664 6 42206807-42217861 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 295.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029133, HPA029134" Supported Approved "Actin filaments,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Actin filaments" "HPA029133: AB_10600084, HPA029134: AB_10600058" "unprognostic (1.06e-1)" "unprognostic (3.90e-2)" "unprognostic (5.55e-2)" "unprognostic (3.77e-3)" "unprognostic (1.70e-1)" "unprognostic (1.78e-3)" "unprognostic (2.37e-2)" "unprognostic (8.65e-2)" "unprognostic (1.50e-3)" "unprognostic (5.13e-3)" "unprognostic (2.78e-3)" "unprognostic (6.29e-2)" "unprognostic (3.17e-2)" "unprognostic (8.54e-2)" "unprognostic (3.45e-1)" "unprognostic (3.36e-2)" "unprognostic (5.04e-2)" 24.7 24.0 16.3 20.3 17.1 24.1 21.6 16.8 18.4 19.4 16.1 20.3 19.1 18.3 18.1 43.3 14.5 15.9 46.6 17.3 17.7 29.1 37.5 15.7 24.3 16.5 16.8 14.6 17.2 22.9 13.2 21.6 16.7 18.4 23.6 18.3 19.9 17.0 73.6 18.4 17.7 22.1 16.1 18.8 18.3 16.2 17.5 24.9 24.1 61.8 27.7 24.2 23.7 18.0 99.4 35.1 36.1 61.8 49.4 47.6 32.2 64.3 63.3 61.0 53.3 40.3 38.2 70.2 41.7 60.2 68.3 35.3 60.3 87.5 81.6 64.5 49.3 62.5 30.9 67.2 51.4 93.1 38.8 41.3 65.9 57.2 121.1 41.4 62.8 73.5 110.5 53.4 74.7 63.5 61.0 67.1 30.7 295.3 57.1 51.7 54.3 66.8 105.1 44.2 55.0 40.6 36.9 49.9 122.0 33.5 83.0 125.2 40.7 51.7 51.0 50.3 96.9 39.6 64.4 149.1 35.3 91.7 52.6 22.4 26.0 20.1 23.9 30.4 28.2 30.1 29.2 28.7 29.4 27.1 29.6 28.9 13.1 29.8 28.8 37.7 35.1 28.0 16.3 17.1 16.8 18.4 17.3 17.7 16.5 16.8 16.7 16.1 17.5 18.0 40.4 22.4 21.6 6.8 41.8 40.5 53.6 61.5 22.8 26.8 35.3 33.4 131.8 20.0 39.6 38.6 31.3 102.0 48.0 25.2 92.0 66.5 7.6 35.3 52.4 41.3 14.9 74.5 7.6 47.0 67.5 42.9 23.4 26.8 32.9 46.1 24.7 58.9 52.8 32.0 9.0 27.6 67.1 24.4 28.0 8.8 28.9 34.8 30.2 2.8 110.6 47.8 60.8 7.5 9.5 61.1 30.5 36.5 41.9 64.9 30.0 86.9 60.5 57.3 19.7 35.2 43.0 75.5 83.8 62.2 40.6 75.4 33.8 65.7 35.3 69.4 MSRA ENSG00000175806 "Methionine sulfoxide reductase A" Q9UJ68 8 10054292-10428891 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 86.0;liver: 64.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 625.8;Inhibitory neurons: 318.6;Oligodendrocyte precursor cells: 268.9;Proximal tubular cells: 666.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 5 "cerebellum: 28.4" "Immune cell enhanced" "Detected in some" "eosinophil: 5.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 12.3" "Low region specificity" "Detected in all" "HPA023804, HPA075766" Approved Supported "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" No No 55000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cytosol" "Plasma membrane, Actin filaments" "HPA023804: AB_1853826, HPA075766: " "unprognostic (1.55e-1)" "unprognostic (4.30e-3)" "unprognostic (1.45e-3)" "unprognostic (1.00e-2)" "unprognostic (4.21e-2)" "unprognostic (1.62e-2)" "unprognostic (1.49e-2)" "unprognostic (6.40e-2)" "unprognostic (9.69e-2)" "unprognostic (1.08e-1)" "unprognostic (1.80e-1)" "unprognostic (4.58e-2)" "unprognostic (1.07e-3)" "unprognostic (6.43e-3)" "unprognostic (4.02e-1)" "unprognostic (6.36e-3)" "unprognostic (3.07e-1)" 17.0 20.4 2.2 1.1 3.0 13.5 16.1 28.4 5.4 9.1 0.0 13.9 1.1 10.7 0.1 11.6 7.4 0.4 29.0 3.8 0.0 86.0 64.0 12.2 0.6 0.0 0.4 6.4 14.5 0.7 9.2 0.8 1.8 9.2 0.6 0.6 10.5 1.0 14.5 9.5 20.1 0.8 0.0 18.6 14.2 15.2 0.3 1.5 9.6 1.3 0.6 11.6 8.2 2.8 0.1 0.9 1.3 4.3 1.2 1.4 0.5 2.5 0.2 0.3 1.7 0.6 2.1 0.0 0.6 2.5 5.8 2.3 0.4 0.1 1.3 0.2 0.0 0.3 1.5 2.2 4.3 0.8 12.3 0.4 3.2 0.3 0.0 1.4 0.6 0.3 0.4 0.2 4.9 0.1 0.0 0.3 0.6 3.3 0.8 1.6 1.3 2.0 1.1 1.1 2.5 1.5 4.6 0.2 0.5 0.4 2.3 2.8 2.6 1.7 2.0 0.4 1.2 0.2 0.1 0.7 4.8 0.8 3.1 0.5 1.9 5.6 0.4 1.2 0.3 0.6 0.4 0.3 1.2 0.1 0.3 0.2 2.2 0.7 0.9 0.2 0.3 0.2 2.2 3.0 28.4 5.4 3.8 0.0 0.0 0.4 1.8 0.0 0.3 2.8 44.1 0.0 7.4 152.8 21.4 16.4 29.3 10.8 14.2 10.1 21.2 21.8 21.6 25.8 7.2 25.8 31.3 7.7 12.4 26.4 92.0 32.3 80.6 13.6 8.7 30.3 9.6 3.4 625.8 47.1 4.6 13.1 14.8 11.8 80.7 13.7 19.6 97.2 47.0 16.8 318.6 20.8 4.1 33.6 48.3 167.9 9.3 38.0 30.2 85.3 22.3 14.6 11.3 268.9 60.7 51.1 37.8 9.8 16.2 33.8 195.5 666.1 5.6 6.2 13.1 11.3 16.9 39.3 26.5 20.1 14.1 8.3 18.0 14.1 24.5 31.1 MTMR9 "C8orf9, DKFZp434K171, LIP-STYX, MTMR8" ENSG00000104643 "Myotubularin related protein 9" Q96QG7 8 11284816-11328146 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 84.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070944 Approved "Actin filaments,Centrosome" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Centrosome "Actin filaments" "HPA070944: AB_2686325" "unprognostic (1.97e-2)" "unprognostic (1.95e-1)" "unprognostic (2.30e-2)" "unprognostic (1.32e-2)" "unprognostic (2.16e-1)" "unprognostic (2.64e-2)" "unprognostic (8.09e-3)" "unprognostic (3.25e-1)" "unprognostic (2.05e-1)" "unprognostic (1.46e-1)" "unprognostic (3.38e-2)" "unprognostic (1.12e-1)" "unprognostic (1.06e-2)" "unprognostic (1.07e-1)" "unprognostic (1.73e-1)" "unprognostic (3.08e-1)" "unprognostic (1.43e-2)" 4.6 3.7 7.8 4.3 7.9 3.4 4.9 7.0 8.1 3.5 3.3 6.5 2.4 4.5 2.9 3.4 3.1 3.2 7.5 8.4 8.7 4.4 3.0 3.5 4.0 7.2 8.4 3.6 2.9 4.2 3.0 4.2 8.0 5.0 3.1 17.5 2.6 3.9 5.7 3.8 3.1 5.8 6.3 3.8 3.0 7.7 7.4 3.5 3.7 8.6 3.9 3.7 3.2 8.1 2.9 4.2 7.1 4.8 8.4 7.1 5.0 8.7 5.6 5.1 4.3 3.7 1.5 6.8 2.1 8.1 5.0 3.7 5.2 5.3 6.7 1.2 3.8 6.8 4.5 3.4 8.9 2.2 5.0 6.9 5.9 6.2 9.1 5.8 7.8 3.8 5.0 3.9 10.5 2.1 3.9 2.6 12.4 6.9 4.0 3.0 9.7 2.0 7.7 5.1 2.2 10.6 4.6 2.7 6.7 10.5 2.7 5.4 11.2 7.9 2.3 4.8 4.8 1.3 1.9 3.3 6.9 5.6 7.9 0.2 0.4 0.3 0.7 0.4 0.5 0.5 0.6 0.5 0.2 1.1 0.7 0.7 0.5 0.5 0.4 1.0 0.4 0.2 7.8 7.9 7.0 8.1 8.4 8.7 7.2 8.4 8.0 6.3 7.4 8.1 17.8 12.8 16.8 26.4 27.7 13.6 11.6 12.9 11.4 0.0 11.7 8.4 25.3 24.3 14.5 14.7 0.0 12.4 27.4 7.4 3.9 11.6 17.7 5.1 15.0 18.9 16.2 10.8 44.8 7.1 12.7 18.3 4.6 8.0 14.0 24.9 26.7 17.3 14.5 0.0 42.1 10.7 12.2 21.0 32.7 8.5 23.3 20.2 16.0 18.7 24.3 0.0 25.7 32.2 48.7 15.0 11.1 19.5 11.7 21.6 13.4 10.9 18.0 0.0 39.5 19.0 17.7 84.9 33.1 10.1 12.9 4.5 20.7 14.6 9.5 9.3 MYH10 NMMHCB ENSG00000133026 "Myosin heavy chain 10" P35580 17 8474207-8630761 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell shape" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 171.9;Excitatory neurons: 221.3;Inhibitory neurons: 151.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 216.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017180, HPA047541, HPA057198" Enhanced Supported "Actin filaments,Mitochondria,Cytosol" NA NA 28000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" "Actin filaments" "Mitochondria, Cytosol" "CAB017180: , HPA047541: AB_2680081, HPA057198: AB_2683364" "unprognostic (4.67e-2)" "unprognostic (9.64e-3)" "unprognostic (1.13e-1)" "unprognostic (2.52e-3)" "unprognostic (2.40e-1)" "unprognostic (2.33e-2)" "unprognostic (2.75e-1)" "unprognostic (6.45e-2)" "unprognostic (4.77e-2)" "unprognostic (1.11e-1)" "unprognostic (1.39e-3)" "unprognostic (1.69e-2)" "prognostic favorable (1.38e-4)" "unprognostic (2.02e-2)" "unprognostic (2.73e-1)" "unprognostic (5.58e-2)" "prognostic unfavorable (6.42e-4)" 27.3 16.9 12.6 6.1 18.9 13.4 14.7 7.0 29.0 19.6 12.6 12.2 2.3 27.8 16.8 6.6 25.2 26.1 38.9 17.9 8.0 32.5 18.9 66.9 6.5 9.6 7.3 25.9 9.8 13.8 17.7 53.4 9.6 17.7 3.8 22.5 6.6 26.6 4.9 7.9 5.8 22.1 0.5 4.6 9.5 7.4 11.0 5.8 13.6 8.2 4.0 10.5 10.3 13.2 54.1 35.1 216.3 72.7 27.7 33.1 97.1 44.2 39.7 52.2 55.8 94.5 8.0 0.5 28.6 43.9 28.4 5.2 108.7 53.0 58.1 1.2 88.3 62.3 21.7 83.0 64.7 5.4 4.2 47.3 18.9 67.7 26.1 32.1 85.3 70.9 88.1 0.2 32.9 21.6 67.2 1.7 102.1 3.6 7.7 105.9 64.2 0.2 59.1 22.3 17.7 96.8 69.2 3.4 68.1 165.0 18.3 3.6 2.8 48.7 35.6 0.3 38.5 8.3 10.8 13.4 0.3 5.0 111.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 12.6 18.9 7.0 29.0 17.9 8.0 9.6 7.3 9.6 0.5 11.0 13.2 43.0 22.4 14.1 43.1 1.1 4.7 9.5 11.2 9.6 37.1 18.7 16.4 33.5 12.8 11.5 101.2 50.1 171.9 1.0 0.8 17.6 13.7 49.1 28.1 37.6 30.6 2.4 43.5 221.3 1.7 88.6 58.0 3.1 28.5 1.3 41.6 55.6 15.3 15.8 35.3 151.1 1.9 6.1 2.7 3.7 28.6 3.7 1.3 1.8 15.9 0.7 25.9 2.1 96.5 15.5 1.9 0.7 39.9 0.6 7.6 0.0 14.0 21.7 39.4 0.0 12.4 23.6 15.6 27.8 9.5 4.0 76.5 2.0 28.0 2.2 4.4 MYH9 "DFNA17, EPSTS, FTNS, MHA, NMHC-II-A, NMMHCA" ENSG00000100345 "Myosin heavy chain 9" P35579 22 36281280-36387967 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell shape" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Alport syndrome, Cancer-related genes, Cataract, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 1343.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001644, CAB015386, HPA064783" Enhanced Supported "Nuclear bodies,Plasma membrane,Actin filaments,Cytosol" No No 410000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Actin filaments" "Nuclear bodies, Cytosol" "CAB015386: AB_784698, HPA001644: AB_1079439, HPA064783: AB_2732721" "unprognostic (1.38e-1)" "unprognostic (9.12e-2)" "unprognostic (4.21e-2)" "unprognostic (6.34e-2)" "unprognostic (1.49e-1)" "unprognostic (3.90e-2)" "unprognostic (9.56e-2)" "unprognostic (8.28e-2)" "unprognostic (5.50e-2)" "unprognostic (6.38e-2)" "unprognostic (1.93e-2)" "unprognostic (1.61e-1)" "unprognostic (7.98e-2)" "unprognostic (9.48e-2)" "unprognostic (1.64e-1)" "unprognostic (1.62e-1)" "unprognostic (2.59e-2)" 295.9 95.5 42.3 181.1 42.1 245.9 231.5 40.6 54.7 181.2 65.5 192.6 107.0 356.4 39.3 153.8 182.2 134.5 161.1 50.8 39.4 140.7 101.6 286.2 161.7 52.7 51.7 121.1 160.3 55.0 52.6 166.5 48.1 131.8 89.8 9.7 177.2 98.4 84.0 160.6 163.5 174.1 48.8 232.5 135.8 38.2 52.1 125.1 141.2 46.3 104.1 168.8 166.8 48.2 612.2 277.0 86.2 74.2 156.8 195.1 437.3 398.4 507.5 554.6 413.2 302.1 170.3 156.9 230.1 666.1 265.0 412.7 125.2 779.4 559.6 356.1 120.9 302.6 294.3 259.9 481.1 346.9 463.8 233.0 234.7 751.9 626.4 540.3 461.8 113.2 67.3 205.8 448.9 161.9 124.4 204.0 51.7 171.1 169.2 233.3 267.3 146.7 314.5 581.5 129.6 53.0 559.7 217.0 251.6 218.5 162.4 177.1 1343.7 1222.6 370.3 237.5 731.5 135.2 114.7 129.0 463.2 172.3 363.1 72.6 25.2 64.7 32.4 19.8 28.4 13.4 23.5 26.4 17.2 11.9 18.3 20.4 41.2 9.0 26.5 8.0 26.3 54.5 42.3 42.1 40.6 54.7 50.8 39.4 52.7 51.7 48.1 48.8 52.1 48.2 303.9 118.6 87.1 12.7 108.4 144.0 182.4 123.1 72.8 2.6 90.5 89.4 62.6 80.1 89.7 92.0 2.1 87.0 151.7 359.8 7.9 309.4 35.8 89.7 121.6 258.7 73.8 51.9 42.5 245.8 193.1 82.9 123.8 194.7 93.1 117.1 132.8 102.8 100.4 82.4 6.7 131.0 59.0 119.6 124.2 37.4 68.0 168.8 85.4 61.8 196.6 11.9 137.0 7.5 33.3 344.6 186.8 211.4 125.9 184.4 159.8 27.5 51.5 5.3 203.8 39.9 275.2 6.9 10.4 133.6 135.1 46.4 213.2 141.3 139.5 134.3 MYLK "MLCK, MLCK1, MYLK1, smMLCK" ENSG00000065534 "Myosin light chain kinase" Q15746 3 123610049-123884332 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "seminal vesicle: 1700.3;smooth muscle: 2137.7" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 728.5;Hepatocytes: 208.7;Peritubular cells: 690.5;Sertoli cells: 276.1;Smooth muscle cells: 448.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 7.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 200.0;BJ hTERT+: 298.2;fHDF/TERT166: 260.2;hTERT-RPE1: 202.7;RPTEC TERT1: 291.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020789, HPA031677, HPA048055" Enhanced Enhanced "Plasma membrane,Actin filaments" NA NA 1500000 "Cluster 34: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Actin filaments" "Plasma membrane" "CAB020789: , HPA031677: AB_10794617, HPA048055: AB_2732543" "unprognostic (2.80e-2)" "unprognostic (5.05e-2)" "unprognostic (5.55e-2)" "unprognostic (2.85e-2)" "unprognostic (1.69e-1)" "unprognostic (1.41e-1)" "unprognostic (4.86e-2)" "unprognostic (8.55e-2)" "unprognostic (1.20e-1)" "unprognostic (1.40e-1)" "unprognostic (8.21e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (2.04e-6)" "unprognostic (5.26e-3)" "unprognostic (9.60e-2)" "unprognostic (3.00e-1)" "prognostic unfavorable (4.46e-4)" 143.6 57.4 37.6 188.7 64.8 3.3 163.4 72.1 42.4 281.3 14.1 551.5 110.9 669.2 232.9 420.6 289.8 250.4 33.6 33.6 46.7 64.4 67.2 85.2 33.6 104.6 64.8 95.9 15.3 11.6 2.6 70.2 99.3 907.6 299.1 13.6 140.1 1700.3 10.0 20.1 125.1 2137.7 55.6 89.5 122.7 50.5 52.2 8.0 22.2 14.9 19.1 505.7 84.8 112.1 14.4 38.4 10.8 7.8 10.8 1.9 4.7 200.0 298.2 137.3 92.1 8.1 7.4 0.6 42.5 260.2 67.0 4.8 5.2 1.8 149.0 0.2 0.7 102.4 0.9 28.9 56.1 0.6 9.8 36.9 3.5 24.4 34.4 202.7 8.9 1.3 1.2 0.5 90.9 1.7 0.2 2.5 12.0 0.5 5.1 13.5 6.8 36.7 291.9 8.5 1.4 6.4 21.8 1.9 3.1 25.0 1.0 0.3 33.4 39.5 13.9 10.3 30.7 3.4 4.2 0.3 104.0 1.0 9.6 7.4 1.6 0.4 0.1 0.2 0.0 0.2 0.0 0.0 3.5 0.1 0.2 0.1 5.0 0.0 0.0 3.3 0.2 20.9 37.6 64.8 72.1 42.4 33.6 46.7 104.6 64.8 99.3 55.6 52.2 112.1 45.9 16.0 38.3 43.4 2.5 20.5 27.2 24.8 1.2 2.9 19.9 728.5 25.2 37.1 5.7 27.6 125.1 0.8 3.5 88.1 3.9 6.0 40.7 45.9 46.6 56.9 11.4 3.2 25.2 3.9 0.8 40.1 3.1 54.4 2.5 3.2 45.3 208.7 4.9 3.3 3.4 3.9 8.2 7.9 37.0 33.8 104.7 20.8 19.6 8.4 1.2 4.7 0.0 5.5 37.0 4.0 18.7 690.5 3.3 8.6 14.2 17.2 17.6 19.9 276.1 5.6 448.7 4.7 4.6 1.3 20.2 2.5 3.2 4.5 4.2 3.7 MYO3A DFNB30 ENSG00000095777 "Myosin IIIA" Q8NEV4 10 25934229-26212532 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hearing, Sensory transduction, Vision" "Actin-binding, Kinase, Motor protein, Myosin, Serine/threonine-protein kinase, Transferase" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "retina: 15.5;testis: 5.2" "Cell type enhanced" "Detected in some" "Early spermatids: 156.6;Late spermatids: 58.2;Muller glia cells: 74.8;Spermatocytes: 31.7" "Cancer enhanced" "Detected in many" "cervical cancer: 1.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.3;CAPAN-2: 1.2;HEK 293: 1.5;SCLC-21H: 1.4;U-2 OS: 2.4;U-698: 6.3" "Not detected" "Not detected" "HPA051893, HPA075413" Enhanced Supported "Plasma membrane,Actin filaments,Cytoplasmic bodies" No No "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" "Actin filaments, Cytoplasmic bodies" "Plasma membrane" "HPA051893: , HPA075413: " "unprognostic (5.00e-3)" "unprognostic (3.36e-2)" "unprognostic (1.53e-1)" "unprognostic (3.20e-3)" "unprognostic (2.96e-1)" "unprognostic (4.37e-2)" "unprognostic (5.29e-2)" "unprognostic (2.74e-1)" "unprognostic (4.31e-2)" "unprognostic (1.03e-1)" "unprognostic (5.66e-3)" "unprognostic (7.96e-3)" "unprognostic (6.34e-2)" "unprognostic (1.46e-2)" "unprognostic (6.62e-2)" "unprognostic (9.69e-2)" 0.1 0.1 0.4 0.0 1.8 0.1 0.1 0.0 0.8 0.1 0.2 0.1 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.1 0.6 0.3 0.0 0.1 0.0 0.6 0.5 0.0 0.7 0.0 0.5 0.0 0.5 0.1 0.3 15.5 0.0 0.1 0.0 0.7 0.1 0.0 0.2 0.0 0.2 5.2 0.3 0.2 0.2 0.1 0.2 0.0 0.3 0.3 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.9 0.8 0.0 0.0 0.7 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.8 0.0 0.8 0.1 0.6 0.6 0.5 0.5 0.2 0.3 0.3 0.2 0.0 0.5 2.0 0.1 1.8 0.3 0.0 0.0 0.9 0.6 0.3 0.6 0.0 2.5 0.0 0.0 0.0 0.0 0.2 1.9 0.8 156.6 0.6 0.1 0.3 1.8 0.0 2.2 0.0 0.4 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 5.9 0.4 0.0 0.0 0.0 58.2 1.2 0.1 0.0 1.9 0.0 74.8 0.0 1.0 0.4 0.2 0.0 1.2 0.0 0.3 0.0 1.0 0.0 3.9 0.0 0.0 2.4 31.7 14.2 2.4 1.0 0.0 0.0 0.0 0.4 0.3 NAA60 "FLJ14154, NAT15" ENSG00000122390 "N-alpha-acetyltransferase 60, NatF catalytic subunit" Q9H7X0 16 3443649-3486953 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Chromosome partition" "Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040916 Approved Uncertain "Actin filaments,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" "Actin filaments, Cytosol" "HPA040916: AB_10794428" "unprognostic (8.59e-2)" "unprognostic (2.16e-3)" "unprognostic (3.39e-1)" "prognostic favorable (3.14e-4)" "unprognostic (1.81e-1)" "unprognostic (5.90e-2)" "unprognostic (2.88e-2)" "unprognostic (1.53e-2)" "unprognostic (5.23e-2)" "unprognostic (5.12e-2)" "prognostic favorable (4.30e-4)" "unprognostic (9.54e-2)" "unprognostic (1.64e-1)" "unprognostic (1.60e-2)" "unprognostic (8.96e-2)" "unprognostic (3.59e-1)" "unprognostic (6.74e-3)" 25.5 45.4 31.5 16.9 30.0 20.1 25.1 37.5 35.9 28.4 22.7 40.4 40.5 31.6 18.7 31.0 28.2 20.3 48.9 31.9 27.5 52.4 67.5 32.0 20.2 30.8 30.5 26.8 47.9 49.1 41.6 19.5 29.3 35.2 22.6 16.3 26.0 23.9 42.9 24.2 39.3 19.1 28.8 42.9 58.9 32.7 31.2 19.5 32.0 21.2 16.7 28.4 23.2 30.3 16.8 61.9 40.1 44.1 26.5 19.4 39.1 26.9 25.0 29.3 26.6 43.9 30.5 31.7 30.0 29.6 21.0 37.4 40.1 31.2 29.4 49.7 27.8 35.4 25.7 53.0 32.9 53.1 45.6 24.4 27.9 20.4 38.9 29.2 45.1 29.4 44.8 41.4 19.4 73.6 33.4 36.3 50.1 35.8 18.1 42.3 30.8 47.5 27.7 29.7 21.6 42.5 45.8 48.3 24.6 38.5 40.2 34.7 30.8 36.0 27.7 12.8 26.7 35.2 33.6 30.5 12.1 29.0 29.2 33.3 18.6 53.8 17.7 20.6 19.2 11.6 15.8 17.7 18.1 11.0 12.3 16.4 20.0 18.4 23.6 11.6 20.1 19.5 31.5 30.0 37.5 35.9 31.9 27.5 30.8 30.5 29.3 28.8 31.2 30.3 26.3 9.6 16.0 24.8 17.7 0.1 13.4 0.1 17.6 21.2 24.5 16.4 15.5 38.6 5.6 12.9 6.2 28.3 22.7 66.7 43.0 30.1 55.7 33.3 25.7 21.0 27.0 18.7 22.2 41.7 40.0 18.0 37.2 30.9 30.4 18.4 26.7 53.5 32.1 11.8 26.5 43.1 0.0 34.8 0.3 54.4 11.5 23.6 0.0 25.3 27.0 29.3 26.8 22.1 34.8 37.0 54.3 15.8 15.4 20.2 84.2 49.0 3.7 15.3 26.3 16.8 17.7 19.6 24.5 16.5 0.3 33.0 22.9 21.1 35.3 23.5 NCOA5 "bA465L10.6, CIA" ENSG00000124160 "Nuclear receptor coactivator 5" Q9HCD5 20 46060991-46089962 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050231 Uncertain Supported "Nucleoplasm,Actin filaments" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Actin filaments" "HPA050231: AB_2681058" "unprognostic (1.78e-1)" "unprognostic (1.54e-1)" "unprognostic (2.43e-2)" "unprognostic (7.93e-2)" "unprognostic (2.30e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (1.41e-5)" "prognostic favorable (8.07e-4)" "unprognostic (2.32e-1)" "unprognostic (7.75e-2)" "prognostic favorable (1.09e-4)" "unprognostic (7.46e-2)" "unprognostic (4.40e-1)" "unprognostic (2.06e-2)" "unprognostic (1.07e-1)" "unprognostic (8.78e-2)" "unprognostic (1.91e-2)" 19.1 17.0 15.8 18.5 16.7 9.5 19.6 21.7 17.4 25.1 17.2 22.2 14.2 24.8 19.4 18.6 21.8 12.2 15.6 16.1 17.6 18.8 15.3 15.2 25.1 16.5 15.7 28.5 20.5 20.3 21.8 18.7 15.2 21.4 16.3 23.1 20.4 14.6 19.6 21.9 21.6 17.7 15.7 25.7 19.2 25.8 16.9 26.2 20.7 14.6 25.0 20.8 19.6 17.4 39.5 34.2 47.4 49.0 22.2 23.3 37.8 26.7 24.0 42.5 34.7 47.8 30.6 64.3 44.0 26.0 36.1 51.2 39.6 33.5 36.5 39.1 19.9 38.7 33.4 40.7 23.5 53.4 36.1 16.8 43.8 22.5 20.4 22.2 30.6 33.1 36.3 50.9 33.9 50.9 74.2 41.3 43.2 33.3 41.8 55.6 31.4 28.0 25.1 44.3 42.5 38.5 42.8 51.7 37.3 26.9 41.1 62.3 28.7 44.6 33.8 27.1 42.2 32.9 50.5 43.2 31.1 31.1 29.1 3.9 9.5 13.4 13.4 10.3 15.4 13.1 14.3 13.6 9.8 17.7 13.3 12.4 7.0 8.8 10.7 21.6 10.0 7.1 15.8 16.7 21.7 17.4 16.1 17.6 16.5 15.7 15.2 15.7 16.9 17.4 7.3 9.6 12.6 24.2 12.5 6.4 3.1 6.7 10.8 13.2 9.7 8.0 5.2 10.0 7.3 9.2 22.9 11.2 11.8 8.2 0.0 8.9 7.5 6.9 11.7 9.1 9.5 9.7 29.4 12.4 8.8 7.9 12.2 7.7 1.3 11.6 9.3 9.3 7.8 3.3 31.6 10.4 4.1 10.1 3.2 5.0 13.7 6.7 3.6 42.2 9.2 7.4 13.4 19.6 35.8 11.7 3.2 15.4 12.1 4.4 4.5 5.2 8.6 9.0 6.6 10.7 7.0 28.1 15.7 8.7 5.4 6.7 8.7 8.4 9.2 3.6 NDC1 "FLJ10407, NET3, TMEM48" ENSG00000058804 "NDC1 transmembrane nucleoporin" Q9BTX1 1 53765478-53838463 "Metabolic proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069751, HPA070882" Approved Supported "Nuclear membrane,Plasma membrane,Actin filaments" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear membrane" "Plasma membrane, Actin filaments" "HPA069751: AB_2686189, HPA070882: AB_2686320" "unprognostic (2.51e-1)" "unprognostic (1.93e-1)" "prognostic favorable (4.48e-5)" "unprognostic (6.96e-3)" "unprognostic (1.31e-1)" "unprognostic (1.36e-3)" "prognostic unfavorable (7.52e-7)" "unprognostic (3.46e-3)" "unprognostic (1.53e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (3.58e-4)" "unprognostic (9.27e-2)" "unprognostic (6.22e-3)" "unprognostic (3.00e-3)" "unprognostic (4.38e-2)" "unprognostic (9.24e-2)" "unprognostic (6.07e-2)" 5.4 5.2 3.4 9.5 3.5 8.4 11.1 3.6 4.1 5.7 3.6 11.9 8.9 6.5 7.4 7.7 7.5 4.6 4.5 3.6 3.4 6.9 7.8 4.7 15.7 3.2 3.3 5.9 4.7 9.5 1.7 8.0 3.3 4.8 14.2 6.0 4.2 5.2 4.3 7.3 8.2 7.1 3.5 5.6 6.4 7.5 3.5 14.2 6.8 5.2 18.4 7.1 4.2 3.9 61.6 31.2 42.8 43.7 15.5 15.5 49.3 40.9 31.0 63.8 51.1 47.5 40.4 119.0 26.2 18.6 51.2 72.0 73.2 43.3 89.8 29.8 50.9 58.5 42.9 40.5 14.3 95.3 31.9 9.4 17.0 62.9 37.5 18.6 39.1 44.2 67.7 16.9 35.6 22.2 47.2 38.2 101.0 52.2 49.9 52.0 68.4 66.0 29.8 41.7 25.4 32.2 36.5 71.5 35.9 45.3 55.3 50.2 22.7 32.9 32.6 45.5 74.9 17.9 48.8 84.7 27.3 71.6 42.2 0.0 2.3 1.5 3.0 5.0 4.7 3.6 2.8 2.7 2.6 2.8 5.3 4.1 0.1 3.1 3.3 2.3 3.4 2.4 3.4 3.5 3.6 4.1 3.6 3.4 3.2 3.3 3.3 3.5 3.5 3.9 4.4 6.4 6.3 12.4 8.7 10.1 6.4 9.0 12.0 4.5 10.1 6.3 8.1 4.3 5.4 5.5 2.1 11.5 5.9 7.9 0.0 8.5 2.3 5.0 5.6 6.1 0.0 19.4 13.8 9.1 20.2 6.3 8.6 4.6 7.6 21.5 5.3 7.1 11.8 3.3 11.0 10.3 16.2 8.2 8.9 2.1 2.8 7.1 7.2 13.1 4.7 3.3 3.1 11.6 19.4 7.0 5.8 3.4 20.1 8.9 2.9 4.5 5.5 2.9 6.6 6.3 15.7 11.8 14.3 18.2 8.5 6.8 6.7 4.3 18.2 6.5 NEGR1 "IGLON4, KILON, MGC46680, Ntra" ENSG00000172260 "Neuronal growth regulator 1" Q7Z3B1 1 71395943-72282539 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 29.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 1968.8;Inhibitory neurons: 1254.4;Oligodendrocyte precursor cells: 726.3;Oligodendrocytes: 442.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 26.7;TIME: 28.5;U-2 OS: 22.9;U-251 MG: 24.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011894 Uncertain Approved "Vesicles,Actin filaments,Cytosol" NA NA 380000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Actin filaments, Cytosol" "HPA011894: AB_1854363" "unprognostic (2.60e-1)" "unprognostic (1.89e-2)" "unprognostic (1.23e-1)" "unprognostic (1.44e-1)" "unprognostic (7.99e-2)" "unprognostic (2.48e-1)" "unprognostic (3.72e-1)" "unprognostic (6.94e-2)" "unprognostic (8.15e-2)" "unprognostic (8.73e-2)" "unprognostic (3.38e-2)" "unprognostic (1.36e-1)" "unprognostic (3.31e-5)" "unprognostic (5.89e-3)" "unprognostic (1.31e-1)" "unprognostic (1.43e-3)" "unprognostic (2.11e-4)" 16.5 5.8 12.8 3.6 15.9 1.2 5.9 4.4 15.7 7.1 0.0 17.5 2.7 5.2 4.1 10.5 7.2 10.7 11.2 15.1 9.1 6.8 0.3 5.5 1.6 1.9 5.6 6.0 4.5 0.7 3.9 2.9 2.7 7.3 7.8 29.8 2.4 5.4 3.3 5.8 5.1 6.4 3.7 0.6 7.4 3.2 12.4 5.6 3.5 5.1 0.8 13.3 6.6 6.5 0.4 0.1 0.8 0.2 26.7 21.0 0.2 19.4 7.2 10.4 12.7 0.1 0.2 0.3 0.1 21.5 0.2 0.6 0.0 0.0 22.4 0.2 0.1 0.1 3.4 0.1 2.2 0.2 0.4 10.2 0.1 8.9 1.5 15.4 12.5 0.3 0.1 0.8 19.5 0.1 0.2 0.2 3.2 0.3 11.0 13.7 20.4 0.3 1.7 0.3 1.5 1.7 6.8 0.1 0.0 0.4 0.1 0.3 28.5 2.3 22.9 0.9 24.5 0.4 0.2 0.1 5.2 13.0 8.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 12.8 15.9 4.4 15.7 15.1 9.1 1.9 5.6 2.7 3.7 12.4 6.5 6.0 0.0 0.5 170.7 0.0 5.0 0.6 0.1 0.0 51.4 0.2 0.5 4.2 1.5 2.5 0.0 27.1 0.0 4.4 0.1 0.0 2.4 6.2 0.1 1.3 2.6 0.0 0.8 1968.8 0.0 0.0 88.7 0.5 0.1 0.0 0.2 0.0 0.0 0.2 1.7 1254.4 0.6 0.0 0.0 16.7 12.5 210.3 2.4 8.8 58.1 3.1 12.2 0.0 726.3 442.7 0.5 0.0 44.8 0.5 1.3 0.0 1.5 7.1 58.7 32.9 8.3 8.5 0.7 2.5 0.3 3.4 0.0 1.1 0.2 0.1 0.7 NEURL1B "DKFZP761M1511, Neur2, RNF67B" ENSG00000214357 "Neuralized E3 ubiquitin protein ligase 1B" A8MQ27 5 172641263-172691540 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 82.8;Distal enterocytes: 82.5;Endothelial cells: 53.8;Leydig cells: 54.7;Paneth cells: 42.1;Proximal enterocytes: 53.4;Smooth muscle cells: 58.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "REH: 43.7;T-47d: 20.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037612 Approved Supported "Actin filaments,Cytosol" NA Yes "Cluster 46: Fibroblasts - ECM organization" "Cluster 14: REH - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Actin filaments" "HPA037612: AB_10795573" "unprognostic (3.56e-2)" "unprognostic (8.46e-2)" "unprognostic (6.72e-3)" "unprognostic (2.70e-1)" "unprognostic (1.64e-1)" "unprognostic (1.55e-1)" "unprognostic (6.58e-2)" "unprognostic (2.95e-1)" "unprognostic (2.86e-1)" "unprognostic (1.09e-1)" "unprognostic (7.13e-3)" "unprognostic (6.81e-2)" "prognostic unfavorable (3.00e-6)" "unprognostic (1.79e-1)" "unprognostic (1.40e-1)" "unprognostic (4.67e-2)" "unprognostic (3.22e-3)" 25.0 16.0 8.4 5.2 10.3 2.0 21.1 2.3 24.1 18.3 3.4 28.4 6.9 24.7 24.1 13.5 22.0 11.7 32.2 17.1 6.9 11.0 6.0 12.6 3.7 3.5 4.6 14.7 5.3 3.2 8.2 6.1 3.8 17.6 13.7 0.3 6.6 32.1 14.0 18.1 17.6 20.4 3.6 0.7 7.7 4.3 6.3 5.9 10.3 16.0 3.9 25.7 17.3 6.5 7.2 3.7 2.0 8.9 0.6 0.3 0.1 8.0 3.5 4.1 6.0 13.7 3.2 0.0 2.1 5.2 5.0 2.1 0.7 3.6 2.8 13.2 0.5 9.8 13.3 0.1 0.6 0.0 2.9 0.0 15.1 0.9 4.1 1.2 0.6 1.4 0.0 3.0 8.9 8.0 2.3 0.2 1.3 3.1 0.3 43.7 9.4 1.4 0.1 1.6 1.6 8.9 7.6 11.9 0.3 3.5 20.0 1.5 1.3 3.1 18.1 2.2 5.1 1.2 0.4 0.0 9.0 0.2 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 10.3 2.3 24.1 17.1 6.9 3.5 4.6 3.8 3.6 6.3 6.5 82.8 0.0 1.9 0.3 0.6 4.8 0.7 3.0 0.6 0.6 1.5 1.3 9.3 1.5 4.8 0.0 0.0 0.3 0.4 82.5 0.0 0.7 2.6 1.9 2.5 53.8 13.9 11.4 5.2 0.7 0.2 10.3 2.0 0.6 0.0 4.9 30.4 0.3 0.3 0.0 1.0 10.2 2.0 1.9 2.6 6.6 54.7 2.2 7.2 4.7 0.7 0.7 0.0 5.0 13.0 4.5 42.1 12.4 0.1 1.9 53.4 0.8 12.8 0.3 26.3 11.6 58.8 2.5 3.4 7.7 5.4 0.1 0.7 2.5 20.0 1.2 NEXN "NELIN, nexilin" ENSG00000162614 "Nexilin F-actin binding protein" Q0ZGT2 1 77888513-77943895 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 404.8;skeletal muscle: 676.9;tongue: 548.9" "Cell type enriched" "Detected in many" 6 "Cardiomyocytes: 2329.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 152.2;LHCN-M2: 135.1;RH-30: 108.5" "Region enhanced" "Detected in all" "basal ganglia: 40.4" "Group enriched" "Detected in all" 4 "basal ganglia: 9.0;midbrain: 13.4;pons: 10.0;thalamus: 25.2" "HPA011185, HPA011904" Approved Supported "Plasma membrane,Actin filaments" NA NA 2900000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Actin filaments" "HPA011185: AB_1854409, HPA011904: " "unprognostic (9.73e-2)" "unprognostic (6.72e-2)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.72e-2)" "unprognostic (1.11e-1)" "unprognostic (1.42e-2)" "unprognostic (1.62e-2)" "unprognostic (1.09e-1)" "unprognostic (3.03e-2)" "unprognostic (2.22e-1)" "unprognostic (1.46e-1)" "unprognostic (3.25e-1)" "unprognostic (5.41e-2)" "unprognostic (5.60e-2)" "unprognostic (2.48e-1)" "unprognostic (9.65e-3)" "unprognostic (3.68e-2)" 42.8 22.3 2.3 24.5 3.1 0.6 16.2 1.7 1.6 21.9 2.5 89.2 10.2 79.0 10.7 49.4 47.5 28.7 404.8 1.3 1.8 8.0 5.6 25.2 5.6 1.4 3.3 15.2 10.0 1.5 1.4 10.6 1.5 62.5 15.7 0.6 11.5 69.8 676.9 6.8 26.7 70.6 1.2 8.6 44.1 5.7 4.7 2.1 10.3 548.9 1.8 49.7 19.5 1.7 26.0 1.5 4.5 0.2 79.5 75.3 12.3 152.2 65.5 29.8 20.2 4.6 0.2 0.0 8.6 54.7 34.4 3.4 3.3 14.3 53.3 0.7 3.4 6.2 7.5 1.5 59.3 1.3 0.2 56.6 3.3 40.7 23.8 65.2 22.8 6.0 0.3 0.0 135.1 0.0 29.9 1.8 23.8 0.0 18.6 24.3 108.5 0.2 35.5 1.2 0.1 1.1 13.3 0.0 1.0 29.9 0.0 3.5 23.4 71.7 53.6 31.2 76.1 0.2 0.2 0.1 4.0 2.8 0.2 0.0 1.7 0.0 0.2 1.0 0.0 0.7 0.1 0.2 0.9 0.5 0.3 0.1 1.4 0.3 0.8 0.6 0.0 3.6 2.3 3.1 1.7 1.6 1.3 1.8 1.4 3.3 1.5 1.2 4.7 1.7 8.3 105.8 4.9 11.4 2.1 1.8 0.9 4.6 1.2 2.7 1.4 33.1 2329.6 0.0 5.4 0.0 4.2 0.8 4.1 0.4 1.9 15.3 24.0 2.6 24.2 17.4 0.0 1.7 26.6 32.4 4.0 93.2 1.1 3.2 1.3 29.7 38.6 1.5 1.2 1.7 27.6 0.5 0.0 4.4 2.2 9.0 73.3 44.9 0.0 16.9 5.8 0.7 0.0 24.6 27.3 21.8 0.1 346.1 0.3 1.3 5.3 0.7 0.4 3.8 216.9 70.4 177.2 0.7 3.6 0.8 0.9 0.3 2.3 13.0 2.1 0.4 NFE2 NF-E2 ENSG00000123405 "Nuclear factor, erythroid 2" Q16621 12 54292111-54301015 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 112.5;lymphoid tissue: 45.3" "Cell type enriched" "Detected in some" 5 "Erythroid cells: 265.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 5 "basophil: 1489.2;neutrophil: 810.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 1489.2" "Group enriched" "Detected in some" 5 "HEL: 376.9;K-562: 168.1;NB-4: 118.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA001914 Enhanced Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Actin filaments" "HPA001914: AB_1079475" "unprognostic (2.68e-4)" "unprognostic (2.93e-2)" "unprognostic (2.20e-2)" "unprognostic (2.31e-2)" "unprognostic (2.33e-2)" "unprognostic (1.85e-1)" "unprognostic (1.20e-2)" "unprognostic (4.55e-2)" "unprognostic (4.12e-1)" "unprognostic (4.55e-2)" "unprognostic (3.47e-2)" "unprognostic (2.57e-3)" "unprognostic (9.90e-6)" "unprognostic (1.81e-2)" "unprognostic (8.99e-2)" "unprognostic (1.51e-2)" "unprognostic (3.46e-2)" 3.8 0.3 0.5 6.2 0.7 112.5 0.6 0.5 1.0 1.4 1.4 0.4 0.5 0.3 0.1 0.8 2.4 1.2 1.9 0.5 0.5 1.4 2.6 13.0 0.3 0.7 0.6 0.2 0.7 1.1 0.9 4.0 0.7 0.5 0.2 0.0 0.5 0.1 1.3 4.8 0.6 1.9 0.5 45.3 0.8 1.2 0.6 1.4 1.4 3.7 0.1 2.3 0.5 0.6 0.3 0.3 0.0 0.0 0.0 0.5 1.4 1.1 6.9 0.7 0.9 5.5 10.0 0.1 0.9 0.9 0.4 0.3 0.0 0.0 0.3 0.0 0.1 376.9 0.9 9.1 0.0 5.8 48.5 0.5 0.1 0.3 0.2 4.4 0.0 0.1 168.1 0.1 0.0 0.1 15.3 118.8 0.1 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 2.6 0.2 0.6 1.8 1.0 18.9 0.3 0.2 0.4 1.1 0.1 0.0 0.0 0.1 0.4 23.4 0.0 1489.2 241.7 232.3 0.6 66.7 1.0 0.3 0.8 0.5 156.7 0.5 1.0 0.7 810.6 1.1 42.0 2.7 0.2 160.2 0.5 0.7 0.5 1.0 0.5 0.5 0.7 0.6 0.7 0.5 0.6 0.6 0.0 0.0 3.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 1.5 0.1 0.0 0.0 0.2 1.3 0.0 0.0 0.1 5.9 0.1 0.0 0.0 0.0 265.6 0.0 0.0 0.5 0.4 0.0 0.1 3.8 0.1 0.4 0.2 1.0 0.0 0.0 0.0 0.0 22.8 0.2 19.0 0.0 44.3 1.8 0.0 33.9 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.8 0.0 0.0 0.1 0.0 0.3 1.3 0.0 0.3 1.2 1.1 0.0 0.1 0.1 NOTCH3 "CADASIL, CASIL" ENSG00000074181 "Notch receptor 3" Q9UM47 19 15159038-15200995 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Sertoli cells: 414.2;Skeletal myocytes: 131.6;Smooth muscle cells: 317.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 66.3;MCF7: 66.9;RT4: 41.2;U-87 MG: 45.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005393, HPA044392" Approved Supported "Nucleoplasm,Actin filaments,Cytosol" NA NA 46000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "Actin filaments" "CAB005393: AB_2151246, HPA044392: AB_2678926" "unprognostic (4.97e-2)" "unprognostic (3.89e-2)" "unprognostic (7.06e-3)" "prognostic unfavorable (5.92e-4)" "unprognostic (9.20e-2)" "unprognostic (1.73e-2)" "unprognostic (2.72e-1)" "unprognostic (9.04e-2)" "unprognostic (3.90e-3)" "unprognostic (1.23e-1)" "unprognostic (1.19e-1)" "unprognostic (3.13e-1)" "prognostic unfavorable (2.53e-7)" "unprognostic (3.35e-2)" "unprognostic (8.34e-3)" "unprognostic (4.40e-2)" "unprognostic (2.00e-3)" 85.7 5.3 14.8 10.4 12.4 0.2 50.5 11.0 21.3 49.4 7.1 14.8 5.5 39.9 16.9 74.3 35.8 23.5 43.6 9.5 11.3 26.0 3.2 38.3 9.2 12.0 15.2 18.9 10.7 12.6 10.3 59.8 14.3 22.0 4.2 0.5 24.4 16.5 29.7 82.1 14.3 16.9 8.2 15.0 11.6 3.8 15.8 34.1 32.3 25.1 10.4 26.3 55.1 10.0 13.0 8.1 66.3 30.3 9.2 7.3 29.8 10.2 0.4 0.4 0.3 15.6 13.4 0.4 7.7 18.9 0.1 15.1 12.1 0.2 0.6 0.1 3.1 0.4 12.4 3.5 4.5 0.0 1.2 8.4 7.3 15.5 1.6 0.6 0.8 4.6 0.5 0.6 1.2 66.9 15.9 0.1 38.8 11.2 0.0 0.1 3.7 0.3 0.0 41.2 1.9 21.4 0.1 37.8 0.0 19.6 40.3 0.1 0.0 1.9 21.0 0.3 0.1 0.1 0.7 0.0 45.7 0.4 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 14.8 12.4 11.0 21.3 9.5 11.3 12.0 15.2 14.3 8.2 15.8 10.0 39.6 9.6 1.5 5.9 0.4 24.1 7.8 17.8 4.6 0.4 41.5 30.7 60.7 0.0 28.5 16.5 0.0 20.2 1.0 0.0 5.9 14.8 0.5 4.8 13.5 32.0 0.0 0.0 0.6 0.0 3.9 24.2 2.0 11.8 0.0 5.9 4.2 0.0 2.8 0.0 0.3 0.3 6.1 10.4 12.3 0.1 9.0 4.1 17.8 13.1 0.7 0.8 0.0 0.0 0.2 0.9 0.1 11.7 0.0 13.0 0.1 0.0 4.2 0.8 414.2 131.6 317.0 0.9 1.2 72.1 72.2 31.5 2.0 1.2 0.2 36.0 NPFFR2 "GPR74, NPFF2, NPGPR" ENSG00000056291 "Neuropeptide FF receptor 2" Q9Y5X5 4 72031804-72148067 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 7.2;seminal vesicle: 3.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 22.1;Cytotrophoblasts: 6.6;Excitatory neurons: 14.5;Extravillous trophoblasts: 12.3;Muller glia cells: 4.9;Syncytiotrophoblasts: 9.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "GAMG: 28.1;NTERA-2: 9.2;RPTEC TERT1: 11.9;SH-SY5Y: 14.0;U-2 OS: 13.7" "Region enriched" "Detected in some" 4 "olfactory bulb: 4.3" "Low region specificity" "Detected in all" HPA026825 Approved "Plasma membrane,Actin filaments" NA NA "Cluster 63: T-cells - Adaptive immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 30: Mammary glandular cells - Lactation" "Plasma membrane" "Actin filaments" "HPA026825: AB_10603123" "unprognostic (1.28e-1)" "unprognostic (1.05e-2)" "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "unprognostic (6.07e-2)" "unprognostic (4.68e-2)" "unprognostic (5.77e-2)" "unprognostic (1.43e-2)" "unprognostic (1.34e-1)" "unprognostic (1.51e-1)" "unprognostic (2.40e-5)" "unprognostic (5.75e-2)" "unprognostic (1.61e-1)" "unprognostic (1.68e-1)" "unprognostic (1.48e-1)" 0.1 0.0 1.0 0.2 0.9 0.0 0.2 0.0 0.6 0.1 0.0 0.1 0.1 0.0 0.9 0.0 0.2 0.1 0.0 0.9 1.1 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 1.6 0.3 0.1 0.2 0.7 0.0 3.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.4 0.2 7.2 0.3 0.2 0.1 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 14.0 0.0 0.0 0.0 2.0 0.0 0.0 1.3 0.0 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.9 0.0 0.6 0.9 1.1 0.5 0.0 0.3 0.0 0.2 0.5 0.1 0.0 0.0 0.7 0.0 0.4 0.0 0.0 0.0 0.0 22.1 0.0 0.5 0.0 0.0 0.0 0.0 6.6 0.0 0.1 0.0 0.2 0.8 0.0 0.0 0.3 0.0 0.0 14.5 0.2 12.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 3.3 3.5 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.5 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 1.7 0.0 0.0 9.7 0.0 0.0 0.0 0.1 NPM3 ENSG00000107833 "Nucleophosmin/nucleoplasmin 3" O75607 10 101781325-101783413 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036295, HPA036296" Approved Approved "Nucleoli,Actin filaments,Cytosol" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" "Nucleoli, Actin filaments, Cytosol" "HPA036295: AB_10671244, HPA036296: AB_10672083" "unprognostic (3.41e-2)" "unprognostic (3.70e-2)" "unprognostic (4.33e-2)" "unprognostic (1.75e-1)" "unprognostic (8.06e-2)" "prognostic unfavorable (1.42e-4)" "unprognostic (1.00e-2)" "unprognostic (1.98e-1)" "unprognostic (5.17e-2)" "unprognostic (1.75e-1)" "unprognostic (2.45e-2)" "unprognostic (1.35e-2)" "unprognostic (2.86e-2)" "unprognostic (3.55e-2)" "unprognostic (1.81e-1)" "unprognostic (5.69e-2)" "unprognostic (9.58e-2)" 12.7 19.5 9.9 18.5 10.2 27.2 19.0 7.8 10.4 19.6 9.6 15.5 8.3 17.2 10.1 26.6 15.3 9.8 8.4 9.6 11.6 16.4 12.3 10.2 23.3 8.4 8.5 20.6 30.3 16.4 12.4 16.3 8.6 13.4 19.3 1.1 15.1 8.2 13.3 16.7 10.7 19.9 8.5 14.8 13.1 17.1 11.6 20.3 11.1 10.1 25.9 20.9 16.7 9.3 94.8 117.2 34.2 226.2 76.5 80.0 36.1 50.0 75.7 75.8 64.4 126.5 117.1 154.8 91.0 56.0 41.6 99.2 192.6 211.8 59.3 66.1 199.8 124.5 50.5 206.0 86.1 286.6 87.4 69.6 100.8 105.2 417.0 39.0 100.6 187.1 156.9 83.7 63.3 173.8 121.0 371.8 60.7 131.1 89.1 93.3 179.2 158.0 75.0 45.8 70.0 45.1 31.2 72.5 144.7 41.8 94.4 59.0 40.1 30.0 95.8 44.8 94.1 36.0 39.9 179.7 41.9 263.4 31.8 0.0 2.8 0.0 3.6 4.0 6.5 4.0 5.9 6.9 6.4 4.8 9.5 9.8 0.1 8.1 0.8 8.3 2.6 5.1 9.9 10.2 7.8 10.4 9.6 11.6 8.4 8.5 8.6 8.5 11.6 9.3 5.1 3.2 5.0 1.0 15.3 62.7 79.6 121.4 28.5 1.4 55.5 54.4 2.9 28.6 32.0 36.8 0.0 91.4 15.6 16.3 78.2 54.0 8.9 7.3 22.1 21.6 24.2 17.9 2.7 41.2 90.6 29.7 13.7 10.5 16.5 19.6 15.0 19.0 68.6 0.0 2.0 33.1 46.8 21.1 69.9 10.9 28.0 18.0 30.2 1.9 14.7 2.5 18.6 1.5 1.0 34.2 12.7 23.7 19.1 118.5 3.1 61.6 16.4 2.0 6.6 47.9 21.6 46.5 91.3 21.3 49.9 60.7 18.5 29.0 46.9 62.8 NPTX2 ENSG00000106236 "Neuronal pentraxin 2" P47972 7 98617285-98629869 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 135.8;pituitary gland: 210.8" "Cell type enhanced" "Detected in many" "Granulosa cells: 93.5;Peritubular cells: 326.1;Sertoli cells: 151.2;Spermatocytes: 85.2;Spermatogonia: 94.8" "Cancer enhanced" "Detected in all" "renal cancer: 41.7" "Region enhanced" "Detected in all" "cerebral cortex: 135.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "LHCN-M2: 717.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB020801, HPA049799, HPA058320" Enhanced Approved "Golgi apparatus,Actin filaments,Centrosome" "Secreted to blood" NA NA 2490000 360000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus, Actin filaments" Centrosome "CAB020801: , HPA049799: AB_2680889, HPA058320: AB_2732621" "unprognostic (1.18e-1)" "unprognostic (9.61e-2)" "unprognostic (1.56e-2)" "prognostic unfavorable (5.46e-5)" "unprognostic (1.91e-3)" "unprognostic (9.20e-2)" "unprognostic (2.42e-2)" "unprognostic (6.04e-3)" "unprognostic (1.11e-1)" "unprognostic (1.74e-1)" "unprognostic (7.64e-2)" "unprognostic (2.35e-1)" "prognostic unfavorable (5.46e-9)" "unprognostic (1.06e-2)" "unprognostic (1.21e-1)" "unprognostic (5.33e-2)" "unprognostic (3.69e-2)" 7.0 39.2 11.2 1.9 13.6 0.5 3.8 10.1 135.8 9.9 2.5 15.3 0.5 5.7 3.5 3.0 2.8 1.1 9.8 39.2 47.3 1.1 2.6 0.9 0.1 13.8 14.5 3.7 21.4 0.6 210.8 0.1 16.2 7.2 0.8 4.7 3.7 1.6 8.9 8.2 5.4 2.5 6.4 13.0 6.7 34.3 45.6 0.5 3.1 6.7 0.3 5.5 6.9 16.8 0.0 0.0 6.5 0.2 0.0 0.5 0.0 8.8 0.0 0.1 0.0 0.0 0.0 0.0 21.1 2.8 1.5 0.0 0.9 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.2 5.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 717.9 0.0 5.7 0.0 35.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.1 33.8 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.1 0.5 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 11.2 13.6 10.1 135.8 39.2 47.3 13.8 14.5 16.2 6.4 45.6 16.8 8.6 0.0 0.6 2.9 0.3 3.8 0.5 0.0 0.0 19.9 0.2 1.4 3.4 5.7 1.3 0.0 4.2 0.0 1.0 4.5 0.0 5.4 12.0 8.5 1.8 16.9 16.0 0.0 22.1 12.8 0.2 11.1 1.5 10.5 0.0 93.5 3.9 0.7 0.5 0.0 5.3 1.2 0.0 0.0 5.4 24.2 14.0 1.3 12.4 5.6 0.0 1.6 0.0 1.0 1.8 2.9 1.1 326.1 1.0 5.2 0.5 0.1 0.0 2.8 151.2 57.2 27.1 85.2 94.8 0.1 3.0 0.1 0.8 12.7 2.3 1.2 NTN1 NTN1L ENSG00000065320 "Netrin 1" O95631 17 9021510-9244000 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.1;heart muscle: 59.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 137.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 27.5;T-47d: 16.6;U-2 OS: 14.4;U-251 MG: 22.1;WM-115: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056419 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" "Secreted to extracellular matrix" NA NA 110000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "Nucleoplasm, Actin filaments" "HPA056419: AB_2683124" "unprognostic (2.72e-1)" "unprognostic (2.59e-2)" "unprognostic (7.12e-2)" "unprognostic (5.25e-2)" "unprognostic (2.51e-1)" "unprognostic (9.33e-3)" "unprognostic (9.42e-2)" "unprognostic (2.20e-1)" "unprognostic (1.63e-1)" "unprognostic (1.33e-2)" "unprognostic (1.89e-1)" "unprognostic (1.15e-1)" "unprognostic (2.49e-2)" "unprognostic (2.20e-2)" "unprognostic (2.60e-1)" "unprognostic (6.07e-3)" "unprognostic (8.31e-3)" 6.4 0.5 4.5 3.6 6.4 0.1 5.3 10.1 4.9 9.3 2.8 14.7 6.7 9.6 3.5 18.9 10.3 7.3 59.4 3.8 7.0 2.0 6.9 4.3 0.2 12.7 37.1 0.9 2.3 4.3 3.0 0.9 14.4 3.9 3.9 0.4 10.9 2.0 2.1 8.1 10.5 6.0 13.8 0.1 17.5 3.1 10.1 2.9 2.0 2.6 2.1 10.2 5.4 8.8 0.1 0.0 1.3 4.6 4.2 0.1 27.5 0.3 0.4 0.3 0.5 0.1 5.7 0.0 6.2 0.0 9.0 0.1 1.2 0.9 0.0 6.4 10.4 1.4 0.0 0.0 0.1 0.5 0.1 0.1 2.1 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.1 5.6 0.1 0.6 1.8 0.0 0.0 3.4 4.8 0.0 0.0 0.3 0.0 0.0 0.1 4.7 1.1 4.5 16.6 0.3 0.0 6.7 14.4 0.0 22.1 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 6.4 10.1 4.9 3.8 7.0 12.7 37.1 14.4 13.8 10.1 8.8 0.7 0.0 0.0 10.7 0.3 3.3 6.6 21.8 9.6 2.9 4.7 4.4 28.1 0.0 23.9 1.8 0.0 0.3 0.2 0.5 0.0 3.1 9.3 5.8 2.0 3.1 0.0 0.0 4.8 1.7 1.2 9.7 1.1 7.9 0.0 0.0 2.2 12.4 0.1 0.0 7.1 1.4 24.4 0.6 5.9 4.6 0.3 0.1 1.8 9.4 0.6 0.3 0.0 137.2 1.0 1.4 0.1 0.0 0.0 4.0 0.7 0.2 11.1 0.2 0.0 3.9 6.8 1.6 2.0 12.7 2.8 0.5 0.5 0.0 0.6 3.5 ONECUT2 OC-2 ENSG00000119547 "One cut homeobox 2" O95948 18 57435374-57491298 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.1;gallbladder: 10.1;intestine: 10.1;liver: 8.5;retina: 5.4" "Cell type enriched" "Detected in many" 5 "Horizontal cells: 964.0" "Group enriched" "Detected in many" 7 "liver cancer: 4.3;pancreatic cancer: 4.3;stomach cancer: 5.4" "Group enriched" "Detected in many" 5 "basal ganglia: 9.1;cerebral cortex: 2.3;hypothalamus: 4.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 20.3;HeLa: 14.1;RT4: 6.7;SCLC-21H: 10.1" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 5 "basal ganglia: 8.7;cerebellum: 4.7;cerebral cortex: 5.6;hippocampal formation: 3.2;hypothalamus: 2.5" HPA057058 Enhanced Supported "Nucleoplasm,Actin filaments" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 20: HeLa - Mitochondria" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Actin filaments" "HPA057058: AB_2683323" "unprognostic (3.02e-2)" "unprognostic (5.36e-2)" "unprognostic (9.06e-3)" "unprognostic (3.79e-5)" "unprognostic (1.13e-2)" "unprognostic (4.48e-4)" "unprognostic (2.10e-2)" "unprognostic (1.81e-1)" "unprognostic (3.75e-1)" "unprognostic (4.56e-3)" "unprognostic (8.66e-3)" "unprognostic (1.16e-2)" "unprognostic (5.34e-4)" "unprognostic (3.83e-2)" "unprognostic (2.58e-1)" "unprognostic (1.13e-1)" "unprognostic (3.21e-1)" 0.0 0.1 0.4 0.0 9.1 0.0 0.0 0.8 2.3 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 10.1 0.0 0.3 4.2 0.1 8.5 0.0 0.0 0.6 0.3 0.0 2.3 0.8 0.8 0.0 0.8 0.0 0.0 5.4 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 1.0 1.2 3.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 1.4 0.0 3.4 0.0 0.1 20.3 3.1 0.7 14.1 3.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 2.3 4.0 0.7 0.0 0.5 1.9 0.0 0.1 1.6 0.7 0.0 1.2 0.0 1.6 6.7 10.1 1.7 0.1 0.0 0.2 0.1 0.5 0.7 0.0 1.0 1.3 0.2 0.2 0.3 3.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 9.1 0.8 2.3 0.3 4.2 0.6 0.3 0.8 0.0 1.0 0.2 0.3 0.0 0.0 2.3 0.0 0.1 0.2 0.0 0.0 4.5 0.4 1.1 2.8 184.5 0.0 7.3 14.6 0.0 0.0 2.0 0.0 79.7 4.9 0.2 0.1 0.5 8.9 0.0 38.7 8.8 0.1 0.3 0.0 0.3 0.0 0.5 5.3 47.0 1.0 964.0 1.8 0.6 0.0 1.3 0.0 3.2 0.3 0.1 0.0 1.0 0.0 3.0 0.0 3.5 1.0 38.7 3.3 0.0 0.0 0.4 0.1 0.1 0.0 5.6 0.0 0.9 0.7 1.9 2.0 0.0 0.1 0.0 0.1 0.2 0.5 0.0 PALLD "CGI-151, KIAA0992, SIH002" ENSG00000129116 "Palladin, cytoskeletal associated protein" Q8WX93 4 168497052-168928457 "Disease related genes, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 527.9;Cardiomyocytes: 591.7;Peritubular cells: 399.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 13.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 304.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035905, CAB070159" Enhanced Supported "Plasma membrane,Actin filaments,Mitochondria,Cytosol" No No 27000 "Cluster 10: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments" "Plasma membrane, Mitochondria, Cytosol" "CAB070159: AB_1726016, HPA035905: AB_2674854" "unprognostic (3.59e-2)" "unprognostic (3.99e-1)" "unprognostic (2.55e-2)" "unprognostic (5.03e-3)" "unprognostic (2.51e-1)" "unprognostic (7.03e-2)" "unprognostic (2.60e-1)" "unprognostic (2.40e-2)" "unprognostic (3.57e-2)" "unprognostic (4.21e-2)" "unprognostic (2.38e-1)" "unprognostic (3.86e-1)" "unprognostic (8.54e-2)" "unprognostic (1.39e-2)" "unprognostic (1.36e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.28e-4)" 65.0 35.5 31.7 49.7 27.3 0.9 43.6 11.1 19.9 146.1 0.0 303.3 29.0 301.5 21.9 122.6 118.4 71.0 180.4 27.9 36.2 42.1 12.4 71.7 16.9 29.8 25.9 62.1 13.2 55.6 11.3 62.1 25.1 137.0 74.9 12.8 40.8 205.7 127.7 34.7 64.1 303.1 21.4 60.5 94.8 35.1 24.7 23.3 38.7 47.3 16.6 280.2 85.3 22.7 82.1 39.6 87.9 53.4 77.2 83.9 123.6 53.7 137.6 47.2 66.7 1.1 4.6 36.6 14.4 23.7 29.0 17.0 54.1 138.8 60.5 73.9 16.6 0.8 112.5 10.4 135.5 0.4 1.0 132.8 84.4 85.5 125.4 115.0 20.8 19.7 0.1 0.5 304.5 3.8 23.8 1.4 24.9 20.8 24.1 8.3 81.4 0.8 5.3 16.4 9.0 46.4 102.8 8.1 7.3 151.2 48.6 0.5 64.4 50.3 192.1 20.7 90.1 47.8 0.7 1.7 41.6 1.0 14.2 13.7 3.1 0.0 4.6 1.8 0.2 0.1 0.5 2.4 2.1 0.1 0.6 1.6 0.7 0.6 1.2 0.2 0.8 1.8 31.7 27.3 11.1 19.9 27.9 36.2 29.8 25.9 25.1 21.4 24.7 22.7 22.7 32.1 9.4 167.8 1.5 93.6 527.9 56.8 76.8 6.0 46.0 107.9 591.7 20.0 58.7 44.1 18.8 52.1 8.1 20.9 1.9 27.6 133.1 52.8 181.2 27.7 44.8 0.8 27.8 51.3 115.6 130.5 59.7 51.0 52.6 21.0 47.8 11.2 24.5 26.9 108.4 30.7 18.3 28.9 23.8 146.4 130.1 36.7 23.2 16.9 52.9 55.1 17.5 182.4 6.5 83.0 18.6 399.4 2.6 167.6 9.8 23.4 85.2 4.0 177.5 115.4 227.8 81.0 7.6 34.1 49.3 22.3 9.2 13.4 29.3 113.0 PALMD "C1orf11, FLJ20271, PALML" ENSG00000099260 Palmdelphin Q9NP74 1 99646113-99694541 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 130.8" "Cell type enhanced" "Detected in many" "Adipocytes: 537.2;Cardiomyocytes: 157.6;Endothelial cells: 219.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 155.2;LHCN-M2: 49.5;TIME: 220.5;U-87 MG: 92.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017959, HPA030549" Supported Supported "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Actin filaments" "Plasma membrane, Focal adhesion sites" "HPA017959: AB_1854949, HPA030549: AB_2673518" "unprognostic (1.48e-2)" "unprognostic (1.15e-2)" "unprognostic (2.05e-2)" "prognostic favorable (9.42e-4)" "unprognostic (7.67e-2)" "prognostic favorable (5.90e-5)" "unprognostic (1.54e-2)" "unprognostic (2.10e-1)" "unprognostic (3.93e-2)" "unprognostic (1.64e-1)" "unprognostic (8.32e-2)" "unprognostic (6.18e-2)" "unprognostic (5.19e-2)" "unprognostic (1.63e-2)" "unprognostic (1.88e-1)" "unprognostic (2.70e-1)" "unprognostic (8.08e-2)" 130.8 43.0 14.6 7.1 11.7 0.0 77.6 10.5 15.3 27.4 45.8 9.5 3.4 33.0 6.1 38.2 22.8 14.6 91.2 13.7 12.7 11.0 57.1 28.4 3.9 12.0 11.8 18.8 4.9 9.2 10.5 43.2 11.5 18.0 6.5 7.5 71.0 7.9 112.6 48.9 8.6 31.4 11.1 6.3 6.1 11.0 14.1 8.0 7.2 66.2 8.6 14.5 15.9 10.4 0.0 0.3 0.4 0.2 7.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 39.2 2.5 0.6 10.8 0.0 0.5 0.1 0.1 0.1 0.0 18.6 26.4 0.0 0.0 0.1 3.9 2.0 0.0 0.0 4.3 155.2 0.0 22.7 0.0 49.5 0.6 0.0 0.0 0.0 1.6 6.8 0.0 38.2 0.1 0.0 8.0 0.9 0.5 0.0 9.9 0.0 1.0 2.3 0.0 220.5 0.0 0.4 16.8 0.0 0.0 0.0 0.1 92.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 11.7 10.5 15.3 13.7 12.7 12.0 11.8 11.5 11.1 14.1 10.4 537.2 6.4 5.6 0.3 0.5 38.5 11.4 49.6 22.2 2.0 20.0 31.8 157.6 32.9 35.9 3.7 0.0 0.4 1.6 0.1 5.9 8.1 74.9 78.7 71.9 219.4 1.8 2.7 1.4 0.2 0.3 19.2 2.0 17.7 1.3 0.0 96.0 57.3 0.6 3.3 1.8 0.0 14.2 2.2 5.5 12.2 9.3 1.7 24.9 73.1 0.0 55.0 0.0 0.5 0.2 4.1 0.0 24.0 0.0 5.9 0.0 0.4 111.5 3.3 0.0 91.3 12.7 0.5 0.6 27.5 46.5 0.3 1.4 110.1 0.1 3.3 PARD6A "PAR-6, PAR-6A, PAR6alpha, TAX40, TIP-40" ENSG00000102981 "Par-6 family cell polarity regulator alpha" Q9NPB6 16 67660946-67662774 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.5;testis: 42.9" "Cell type enriched" "Detected in many" 4 "Late spermatids: 266.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "REH: 27.9;RPMI-8226: 24.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009733, HPA041551" Approved Supported "Cell Junctions,Actin filaments,Cytosol" No No "Cluster 24: B-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" "Cell Junctions, Actin filaments" Cytosol "CAB009733: AB_2159676, HPA041551: AB_2677545" "prognostic favorable (5.40e-4)" "unprognostic (6.18e-2)" "unprognostic (1.77e-1)" "unprognostic (1.33e-2)" "unprognostic (7.63e-2)" "unprognostic (4.08e-3)" "unprognostic (1.23e-2)" "unprognostic (1.27e-1)" "unprognostic (6.59e-2)" "unprognostic (2.09e-1)" "unprognostic (1.98e-3)" "unprognostic (9.13e-2)" "prognostic favorable (3.08e-7)" "unprognostic (9.22e-3)" "unprognostic (6.69e-2)" "unprognostic (1.25e-1)" "unprognostic (1.39e-2)" 3.2 8.0 25.1 2.4 24.8 1.3 2.8 32.4 38.5 2.1 19.3 7.7 1.1 2.6 2.1 2.0 2.7 1.9 4.2 28.1 22.3 8.8 6.5 3.1 3.1 25.3 22.8 3.9 27.9 6.6 30.2 0.7 26.8 3.6 1.0 2.7 2.7 2.7 8.7 1.8 4.1 1.6 21.9 4.8 5.9 42.9 25.8 3.4 2.4 5.3 2.2 3.7 1.7 25.4 8.9 9.4 2.6 23.5 1.7 0.4 4.7 0.2 1.1 3.4 3.2 4.7 3.6 14.8 4.3 0.3 1.2 7.0 5.2 1.1 0.7 6.9 5.0 6.0 4.1 5.5 2.4 2.5 13.5 0.1 0.5 3.2 1.3 2.1 1.7 21.7 0.6 3.4 0.6 8.7 15.6 3.2 3.3 12.0 6.0 27.9 1.7 24.5 8.8 5.1 21.8 11.7 1.4 3.2 3.7 0.7 19.9 0.9 1.4 0.3 0.8 2.1 4.6 3.5 12.1 13.5 2.6 5.3 1.0 2.1 0.9 0.4 4.3 0.6 7.8 10.9 5.9 5.4 1.1 8.3 2.8 2.2 3.4 1.3 0.1 5.1 6.3 2.0 25.1 24.8 32.4 38.5 28.1 22.3 25.3 22.8 26.8 21.9 25.8 25.4 4.4 3.2 5.8 2.0 17.0 0.9 2.2 1.6 1.2 11.1 7.7 6.7 1.7 10.0 2.6 20.2 4.2 5.7 8.2 3.5 33.2 7.2 61.0 4.1 0.5 3.2 34.0 4.0 7.2 15.0 0.4 3.3 6.1 2.7 5.7 5.2 3.9 4.6 4.3 32.0 7.3 3.3 0.0 4.1 5.7 266.5 3.7 4.7 5.4 3.7 2.2 19.1 1.0 2.0 2.2 6.0 2.1 1.5 12.1 2.1 2.9 16.3 3.4 10.1 0.0 8.0 9.7 5.5 3.9 1.4 1.6 2.9 15.0 1.9 4.7 2.4 PARVA "FLJ10793, FLJ12254, MXRA2" ENSG00000197702 "Parvin alpha" Q9NVD7 11 12377563-12535356 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion, Cell shape, Chemotaxis, Cilium biogenesis/degradation" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.0" "Lineage enriched" "Detected in single" 11 "T-cells: 1.0" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 229.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005964 Approved Supported "Actin filaments,Focal adhesion sites,Cytosol" NA NA 7300000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Actin filaments, Focal adhesion sites" Cytosol "HPA005964: AB_1079569" "unprognostic (3.87e-2)" "unprognostic (7.38e-2)" "unprognostic (3.30e-2)" "prognostic favorable (1.76e-4)" "unprognostic (7.37e-3)" "unprognostic (1.38e-2)" "unprognostic (6.78e-2)" "prognostic unfavorable (8.19e-4)" "unprognostic (1.76e-2)" "unprognostic (2.80e-2)" "unprognostic (1.70e-2)" "unprognostic (9.82e-2)" "unprognostic (6.73e-2)" "unprognostic (6.58e-3)" "unprognostic (1.35e-1)" "unprognostic (1.50e-1)" "unprognostic (3.82e-2)" 61.8 17.6 9.3 22.7 9.0 0.1 40.9 7.2 10.1 53.9 16.5 92.4 17.5 71.8 16.7 42.8 38.8 31.9 34.3 9.8 11.6 23.0 16.9 28.8 6.4 11.0 7.3 31.9 36.0 16.9 11.7 35.9 8.4 50.6 38.4 8.9 20.9 68.9 8.1 14.0 26.1 95.5 11.3 11.3 42.5 6.8 8.6 4.6 17.9 11.7 9.1 55.0 28.2 11.0 34.0 33.1 30.2 39.4 147.8 110.6 69.1 126.5 130.1 87.7 81.6 24.7 51.8 0.0 41.1 229.5 9.9 20.7 0.4 66.4 104.0 0.6 14.9 0.1 42.4 18.7 114.7 0.1 0.9 91.3 22.3 37.1 57.4 107.5 110.9 0.0 0.1 0.3 131.8 20.4 0.0 0.2 14.2 20.2 26.4 0.0 75.2 0.2 44.9 32.8 4.8 0.1 97.6 39.1 65.5 66.9 18.4 0.9 138.2 105.1 43.8 57.2 35.4 0.1 0.1 0.2 58.5 0.1 118.3 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 9.0 7.2 10.1 9.8 11.6 11.0 7.3 8.4 11.3 8.6 11.0 37.0 99.3 33.0 47.3 1.1 13.8 25.0 29.3 20.5 4.3 24.4 24.8 45.1 18.6 27.0 27.6 0.0 39.9 0.7 39.6 39.2 56.1 0.9 26.9 62.5 33.3 27.1 0.0 31.4 67.1 92.2 59.1 24.5 35.9 5.1 34.8 39.7 19.1 6.5 0.0 34.9 26.2 18.3 1.8 8.8 2.5 41.0 2.0 46.2 36.5 1.0 25.3 0.0 30.7 1.0 51.7 25.4 51.9 0.2 33.5 23.1 38.1 54.8 2.5 52.6 32.6 60.6 1.1 3.4 20.2 8.9 19.0 2.3 25.1 32.4 25.1 PAWR "par-4, PAR4" ENSG00000177425 "Pro-apoptotic WT1 regulator" Q96IZ0 12 79574979-79690964 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 273.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 2.7;naive B-cell: 2.8;NK-cell: 1.4" "Group enriched" "Detected in many" 5 "B-cells: 2.8;NK-cells: 1.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012640, CAB020779" Approved Approved "Plasma membrane,Actin filaments" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "CAB020779: , HPA012640: AB_1855748" "unprognostic (2.42e-1)" "unprognostic (5.58e-2)" "unprognostic (9.77e-3)" "unprognostic (5.39e-2)" "unprognostic (9.44e-3)" "unprognostic (4.21e-3)" "unprognostic (9.21e-2)" "unprognostic (1.37e-1)" "unprognostic (4.78e-1)" "unprognostic (3.03e-1)" "unprognostic (2.42e-3)" "unprognostic (4.97e-3)" "unprognostic (2.22e-2)" "unprognostic (2.58e-2)" "unprognostic (4.64e-1)" "unprognostic (2.22e-1)" "unprognostic (4.23e-2)" 11.0 6.1 6.8 9.0 8.0 3.1 13.4 4.8 3.6 20.9 21.6 16.7 11.7 28.0 15.9 14.3 24.7 8.5 5.2 4.7 7.6 12.6 13.3 11.6 6.9 7.7 13.4 20.4 11.6 13.3 8.7 6.2 5.5 14.9 15.3 0.7 14.3 21.8 1.7 16.5 12.1 16.7 5.5 6.2 13.6 10.9 12.4 4.3 16.2 1.8 6.6 16.1 16.4 5.5 54.5 49.1 8.8 0.3 4.4 1.9 58.6 34.1 9.9 17.0 10.3 61.5 20.2 36.2 61.2 19.0 12.2 59.2 31.0 25.7 24.3 14.7 42.2 0.0 28.7 27.1 23.6 0.5 1.0 4.1 53.4 13.4 76.0 63.0 28.7 14.8 2.1 4.9 18.8 41.0 8.8 0.2 42.6 15.7 27.7 0.0 20.2 23.5 32.4 40.4 25.4 0.1 60.8 31.8 5.7 29.4 28.5 0.3 43.2 25.4 22.8 0.9 23.1 15.3 21.6 26.8 4.2 0.1 11.2 0.4 0.0 0.0 0.0 0.0 0.0 2.7 0.1 0.1 0.2 2.8 0.2 0.2 0.2 1.4 0.0 0.1 0.0 0.0 6.8 8.0 4.8 3.6 4.7 7.6 7.7 13.4 5.5 5.5 12.4 5.5 51.3 80.1 40.7 16.6 33.1 200.1 170.3 42.0 63.2 6.4 93.6 77.3 21.0 60.1 59.2 66.2 0.0 57.1 4.6 103.9 17.6 57.3 62.6 75.7 50.9 31.0 68.8 4.6 1.5 38.5 81.4 41.7 32.1 157.5 1.3 87.4 13.6 54.5 6.5 16.8 50.9 120.9 32.6 1.6 19.2 96.3 84.8 5.3 17.8 23.4 0.4 2.5 4.1 30.7 0.9 83.2 72.0 91.0 11.4 273.4 44.3 47.2 49.9 1.4 85.5 18.3 109.7 98.4 62.1 76.6 179.6 76.9 6.7 62.9 92.7 169.5 PDLIM1 "CLIM1, CLP-36, CLP36, hCLIM1" ENSG00000107438 "PDZ and LIM domain 1" O00151 10 95237572-95291012 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 675.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 805.9;Basal respiratory cells: 763.8;Paneth cells: 769.2;Proximal enterocytes: 1059.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "eosinophil: 189.7;memory B-cell: 223.8;naive B-cell: 213.0" "Group enriched" "Detected in all" 7 "B-cells: 223.8;granulocytes: 189.7" "Cell line enhanced" "Detected in many" "HaCaT: 766.3;Hep G2: 635.3;HHSteC: 731.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017010, CAB072838, CAB072840" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments" NA NA 93000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Actin filaments" "Plasma membrane, Cell Junctions" "CAB072838: , CAB072840: , HPA017010: AB_1855147" "unprognostic (1.61e-1)" "unprognostic (2.87e-2)" "unprognostic (2.58e-2)" "prognostic favorable (1.14e-5)" "unprognostic (3.18e-2)" "unprognostic (7.54e-2)" "unprognostic (2.07e-1)" "unprognostic (8.99e-2)" "unprognostic (2.26e-1)" "unprognostic (2.82e-3)" "unprognostic (5.77e-2)" "unprognostic (6.56e-2)" "unprognostic (1.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.97e-1)" "unprognostic (4.21e-3)" "unprognostic (1.11e-1)" 301.7 32.4 10.7 91.5 10.8 25.0 236.0 10.2 18.5 133.1 30.2 220.0 179.4 115.0 91.8 182.3 155.3 114.9 393.2 11.7 10.9 82.8 160.3 337.2 104.5 20.4 12.7 35.6 98.3 65.9 29.5 141.1 14.1 116.9 218.5 36.9 166.1 114.7 675.1 136.8 249.0 146.0 14.0 148.3 148.3 13.7 13.8 105.9 194.7 290.0 123.7 276.3 165.3 11.2 274.4 181.8 12.4 0.4 64.1 43.3 277.1 82.6 266.4 218.8 356.5 387.0 429.8 0.3 21.9 233.8 110.4 766.3 91.5 498.1 220.6 0.2 132.0 277.9 50.1 635.3 731.0 0.1 13.2 125.5 257.0 111.9 400.6 233.2 396.8 24.2 60.0 70.3 52.7 51.4 0.8 4.9 24.6 137.7 137.2 234.1 10.0 98.4 114.4 268.9 48.3 18.9 91.2 84.6 0.9 293.8 68.2 125.7 345.1 84.5 19.7 0.7 0.7 31.2 0.1 91.6 92.5 0.2 41.0 0.4 2.4 189.7 11.9 0.8 0.1 223.8 2.3 14.1 31.0 213.0 0.5 8.1 7.5 8.9 1.5 3.2 2.2 44.5 10.7 10.8 10.2 18.5 11.7 10.9 20.4 12.7 14.1 14.0 13.8 11.2 435.0 76.9 123.5 0.0 145.6 366.3 805.9 763.8 244.7 10.1 100.6 131.4 266.2 223.1 250.2 51.5 29.2 538.2 20.5 657.0 15.6 420.1 8.4 218.6 319.3 359.3 101.3 41.6 0.9 172.5 116.7 149.2 100.9 113.0 12.6 47.2 459.7 100.4 50.0 1.7 0.4 488.9 152.5 19.4 105.2 8.0 5.0 88.8 40.9 2.8 8.8 11.6 32.0 0.0 0.0 227.0 769.2 0.7 103.5 256.5 1059.7 109.0 316.4 59.5 315.5 21.0 213.1 4.3 35.7 170.4 197.9 117.0 25.8 1.9 419.2 554.3 PDLIM2 ENSG00000120913 "PDZ and LIM domain 2" Q96JY6 8 22578279-22598025 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 793.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in all" "white matter: 429.2" "Low region specificity" "Detected in many" HPA003880 Approved Supported "Actin filaments,Focal adhesion sites" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Actin filaments, Focal adhesion sites" "HPA003880: AB_1855149" "unprognostic (1.04e-1)" "unprognostic (3.53e-2)" "unprognostic (1.80e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-3)" "unprognostic (9.33e-2)" "unprognostic (3.69e-2)" "unprognostic (4.55e-2)" "unprognostic (1.79e-2)" "unprognostic (1.22e-3)" "unprognostic (1.52e-1)" "unprognostic (3.37e-1)" "prognostic unfavorable (1.37e-7)" "unprognostic (6.14e-2)" "unprognostic (8.17e-2)" "unprognostic (3.47e-2)" "unprognostic (3.08e-3)" 66.0 31.6 40.6 31.9 42.2 23.7 51.0 51.0 56.6 85.1 42.6 86.9 60.9 80.2 9.8 131.4 56.0 52.8 51.4 36.9 43.9 77.7 59.4 88.8 54.4 56.6 52.9 49.6 53.7 9.8 35.3 40.5 59.4 45.5 11.2 2.0 48.6 30.9 201.9 153.1 64.3 23.2 49.9 232.0 38.8 12.2 49.9 20.4 27.4 60.9 24.4 57.5 91.7 54.8 90.3 54.5 36.2 63.9 69.9 118.5 40.9 139.1 102.4 97.6 98.5 62.4 14.7 36.9 38.4 126.4 18.1 44.7 20.5 95.0 19.0 0.1 14.1 11.6 35.2 46.1 88.2 13.0 85.9 127.2 11.6 48.2 13.2 76.8 54.2 20.2 3.3 23.4 67.4 46.5 16.7 15.4 29.8 37.8 5.5 13.3 6.9 3.9 17.3 18.3 11.3 26.9 29.1 78.1 128.7 21.3 27.5 25.8 68.2 105.7 108.6 127.9 64.8 0.4 0.8 12.5 109.0 51.3 79.6 78.2 48.0 162.3 47.0 64.4 42.2 25.0 35.5 46.9 38.4 27.6 23.8 35.4 101.6 28.1 63.8 24.7 40.7 34.6 40.6 42.2 51.0 56.6 36.9 43.9 56.6 52.9 59.4 49.9 49.9 54.8 85.8 76.9 13.1 5.5 45.0 95.1 12.9 48.1 39.9 3.0 34.0 42.5 10.2 18.6 34.2 18.4 0.0 73.1 70.9 92.0 15.6 24.9 1.0 8.8 94.0 48.7 1.2 10.5 3.2 26.1 115.1 98.9 7.7 13.8 27.3 25.7 86.4 49.4 59.0 3.3 2.3 12.6 20.3 59.1 73.8 3.4 132.0 37.9 48.0 8.4 42.5 33.1 122.6 7.1 3.9 93.2 126.1 218.2 6.8 52.7 217.6 146.3 5.2 3.6 59.2 27.1 108.3 0.7 6.3 39.7 100.7 793.0 71.6 21.0 15.0 30.6 PDLIM4 RIL ENSG00000131435 "PDZ and LIM domain 4" P50479 5 132257696-132273454 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 315.5;Prostatic glandular cells: 473.0;Skeletal myocytes: 225.2;Urothelial cells: 381.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 91.8;HBEC3-KT: 109.2;HHSteC: 103.7;hTEC/SVTERT24-B: 117.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011912 Uncertain Approved "Actin filaments,Cytosol" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments, Cytosol" "HPA011912: AB_1856277" "unprognostic (1.36e-3)" "unprognostic (1.93e-1)" "unprognostic (1.62e-2)" "unprognostic (8.08e-3)" "unprognostic (4.70e-3)" "unprognostic (2.01e-2)" "unprognostic (1.89e-1)" "unprognostic (2.39e-1)" "unprognostic (1.34e-1)" "unprognostic (3.38e-2)" "unprognostic (3.94e-2)" "unprognostic (4.20e-2)" "unprognostic (5.84e-3)" "unprognostic (1.13e-2)" "unprognostic (2.61e-1)" "unprognostic (3.57e-2)" "unprognostic (3.40e-3)" 24.8 6.6 14.5 18.6 13.8 0.7 34.5 17.9 17.8 36.5 20.1 104.9 6.9 90.7 17.7 50.0 48.3 20.5 61.6 15.8 23.8 33.3 1.2 10.5 4.5 27.7 20.5 28.4 6.5 4.9 28.2 8.0 21.3 50.2 4.8 2.6 47.4 28.1 5.4 64.4 27.2 42.9 22.5 6.7 32.2 6.3 17.9 6.6 14.2 2.6 10.1 59.4 39.1 21.7 46.6 0.0 9.7 0.1 13.2 36.7 3.3 12.9 6.3 12.9 4.2 0.0 4.3 0.3 8.6 68.4 65.8 91.8 0.0 109.2 6.1 0.2 5.1 0.0 0.0 2.2 103.7 0.0 0.3 46.5 7.8 117.6 43.7 45.9 74.0 0.0 20.2 0.1 57.6 0.0 0.0 0.3 3.4 0.0 28.1 2.2 66.4 0.2 29.0 0.0 0.0 39.0 29.7 0.0 0.0 7.7 0.1 4.8 47.9 46.3 49.9 48.4 72.9 0.1 0.1 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 14.5 13.8 17.9 17.8 15.8 23.8 27.7 20.5 21.3 22.5 17.9 21.7 10.1 0.0 4.4 5.5 0.7 105.7 315.5 183.8 76.2 0.5 38.2 149.5 6.8 0.0 57.0 14.7 2.1 5.1 0.8 0.6 107.6 121.5 14.2 21.1 81.0 69.8 16.8 0.0 0.7 9.9 14.4 85.1 6.1 17.9 4.5 10.7 21.0 0.3 6.6 0.0 0.6 16.6 61.1 0.3 32.5 15.8 36.4 3.4 165.4 3.7 1.0 17.7 0.0 0.0 0.3 105.7 154.6 27.4 0.0 473.0 5.6 8.9 138.3 0.7 26.3 225.2 53.8 9.9 13.9 47.8 82.8 22.8 4.2 2.0 5.5 381.7 PDLIM7 ENIGMA ENSG00000196923 "PDZ and LIM domain 7" Q9NR12 5 177483394-177497606 "Predicted intracellular proteins" "Differentiation, Osteogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 570.3;skeletal muscle: 661.5" "Cell type enhanced" "Detected in many" "Ductal cells: 164.8;Exocrine glandular cells: 242.1;Pancreatic endocrine cells: 320.1;Peritubular cells: 223.0;Sertoli cells: 164.3;Smooth muscle cells: 157.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 177.1;eosinophil: 121.2;neutrophil: 438.7" "Lineage enriched" "Detected in all" 9 "granulocytes: 438.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018794, HPA048815" Approved Enhanced "Actin filaments,Focal adhesion sites" NA NA 1700000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Actin filaments, Focal adhesion sites" "HPA018794: AB_1855155, HPA048815: AB_2680530" "unprognostic (7.70e-3)" "unprognostic (3.75e-2)" "unprognostic (9.27e-3)" "prognostic unfavorable (5.45e-4)" "unprognostic (1.40e-1)" "unprognostic (3.48e-2)" "unprognostic (9.18e-3)" "prognostic unfavorable (4.07e-4)" "unprognostic (5.01e-2)" "unprognostic (3.10e-1)" "unprognostic (7.24e-2)" "unprognostic (1.88e-1)" "prognostic unfavorable (6.19e-10)" "unprognostic (6.72e-3)" "unprognostic (3.02e-1)" "unprognostic (1.93e-1)" "unprognostic (3.68e-2)" 74.3 26.7 23.0 74.5 27.2 50.3 58.2 18.8 39.8 183.7 30.2 570.3 31.5 489.5 28.8 64.5 236.0 45.0 79.9 22.3 27.6 52.8 16.0 84.7 15.1 23.9 23.4 94.2 15.1 9.6 66.3 33.2 24.9 245.3 24.9 5.7 42.3 200.7 661.5 38.0 111.7 177.6 20.8 84.5 156.1 37.6 28.5 11.5 37.1 70.5 7.6 315.4 125.0 20.5 115.8 25.8 120.7 89.4 32.5 59.9 118.9 232.4 132.8 128.9 89.0 50.9 109.6 20.4 220.4 156.4 69.5 59.5 19.7 160.6 30.3 27.5 27.6 73.6 92.2 52.6 83.6 38.8 237.3 132.0 29.1 115.6 51.5 191.9 85.4 18.3 52.4 15.3 102.5 103.9 7.0 88.6 75.7 23.2 108.8 144.4 101.3 14.0 89.1 29.6 17.5 35.8 91.5 16.9 44.6 39.9 24.3 31.3 292.9 153.8 168.1 60.5 211.7 4.0 4.7 24.1 73.3 44.2 35.7 177.1 46.7 121.2 5.3 22.9 6.3 9.6 3.1 7.2 26.7 5.3 3.0 4.0 438.7 2.3 29.3 1.9 7.0 23.9 23.0 27.2 18.8 39.8 22.3 27.6 23.9 23.4 24.9 20.8 28.5 20.5 36.6 0.0 0.6 11.1 7.5 14.5 47.1 106.8 6.2 6.3 7.6 65.3 21.0 4.3 20.9 25.8 14.6 12.5 4.4 5.5 25.4 164.8 27.0 7.5 44.8 51.0 3.5 9.4 13.9 242.1 53.3 65.0 9.7 7.3 17.2 18.6 51.0 1.6 64.0 8.4 7.4 2.1 36.7 16.6 18.3 49.3 44.7 44.9 10.6 5.6 31.0 16.2 1.0 2.0 1.7 320.1 33.6 223.0 3.2 30.4 1.0 15.7 13.2 22.6 164.3 24.6 157.7 11.6 38.7 12.2 15.8 14.1 10.8 18.2 3.1 25.3 PDRG1 "C20orf126, dJ310O13.3" ENSG00000088356 "P53 and DNA damage regulated 1" Q9NUG6 20 31944337-31952046 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 55.4" "Cell type enhanced" "Detected in all" "Spermatocytes: 86.8;Theca cells: 170.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047084, HPA063542" Approved Approved "Actin filaments" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 39: CACO-2 - Unknown function" "Cluster 52: Non-specific - Transcription" "Actin filaments" "HPA047084: AB_2679925, HPA063542: AB_2685035" "unprognostic (2.17e-1)" "unprognostic (9.77e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (1.69e-4)" "unprognostic (8.51e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (2.62e-5)" "unprognostic (1.01e-1)" "unprognostic (1.70e-1)" "unprognostic (1.59e-1)" "unprognostic (3.82e-3)" "unprognostic (2.44e-2)" "unprognostic (1.30e-1)" "unprognostic (1.22e-1)" "unprognostic (3.04e-2)" "unprognostic (1.66e-1)" "unprognostic (1.00e-2)" 9.0 12.7 17.7 7.7 18.1 17.0 11.0 20.6 19.2 10.1 19.0 11.1 8.3 8.9 12.8 13.8 10.0 5.7 11.8 18.2 18.2 15.7 14.3 8.2 11.8 19.9 18.3 9.5 9.8 55.4 11.3 11.1 19.9 11.6 6.9 9.6 8.7 15.1 15.2 11.5 8.9 7.6 18.8 13.2 9.7 38.0 18.3 12.3 10.4 15.9 12.5 10.0 10.1 20.0 36.6 29.2 17.8 19.7 10.0 7.4 32.9 28.8 16.1 42.3 23.8 107.7 17.9 36.4 21.6 13.6 31.1 23.2 37.8 28.9 34.1 13.4 25.2 50.8 21.7 37.8 25.3 29.3 20.2 9.1 20.9 29.8 30.5 17.9 17.8 37.9 51.7 18.2 17.8 44.3 38.3 34.3 36.7 37.6 61.0 29.6 53.6 19.2 27.8 19.5 42.1 20.2 87.2 27.8 53.6 18.3 48.5 35.5 16.3 34.2 40.3 31.7 36.8 13.3 14.9 40.0 22.9 103.4 22.9 13.4 10.4 16.7 19.0 14.9 18.4 35.4 20.2 20.8 15.8 36.2 27.0 23.6 4.3 28.7 21.6 29.9 21.2 18.2 17.7 18.1 20.6 19.2 18.2 18.2 19.9 18.3 19.9 18.8 18.3 20.0 22.9 19.2 9.7 4.2 23.4 25.5 16.1 14.0 23.9 21.2 26.7 22.7 17.6 14.3 9.1 11.0 14.6 45.8 29.4 9.6 33.2 24.8 11.8 16.7 20.2 22.9 22.0 13.9 6.3 21.2 26.7 22.3 6.6 18.8 33.0 27.7 12.5 7.9 26.2 16.8 5.9 12.6 10.2 9.1 17.8 17.4 16.1 12.4 12.4 5.6 37.4 23.2 13.4 4.0 5.9 23.8 15.0 17.0 14.8 17.8 13.9 19.3 10.0 21.2 26.3 17.2 22.7 86.8 38.1 18.0 28.6 20.4 18.4 170.9 13.4 14.7 PHOSPHO1 ENSG00000173868 "Phosphoethanolamine/phosphocholine phosphatase 1" Q8TCT1 17 49223366-49230787 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Mineral balance" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 103.0" "Cell type enriched" "Detected in some" 6 "Late spermatids: 1499.6" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 160 "eosinophil: 171.1;neutrophil: 426.7" "Lineage enriched" "Detected in many" 228 "granulocytes: 426.7" "Cell line enhanced" "Detected in some" "Daudi: 5.7;EFO-21: 3.2;HDLM-2: 4.1;SuSa: 5.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA065025 Approved "Plasma membrane,Actin filaments" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "Actin filaments" "Plasma membrane" "HPA065025: AB_2732727" "unprognostic (1.37e-1)" "unprognostic (3.01e-3)" "unprognostic (7.53e-2)" "unprognostic (4.41e-3)" "unprognostic (1.57e-1)" "unprognostic (4.70e-2)" "unprognostic (1.44e-1)" "unprognostic (1.39e-2)" "unprognostic (2.04e-1)" "unprognostic (6.88e-2)" "unprognostic (1.02e-2)" "unprognostic (2.88e-1)" "unprognostic (2.03e-1)" "unprognostic (1.45e-1)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (1.87e-1)" 2.5 1.3 1.5 3.4 3.4 19.0 0.5 6.3 3.9 0.4 0.6 0.7 2.9 0.7 0.2 1.0 1.3 2.2 1.8 1.8 7.3 1.3 1.0 2.3 1.6 8.8 6.2 0.3 1.2 0.2 0.6 6.4 7.4 0.8 0.0 0.7 1.2 0.3 3.4 1.3 3.0 0.4 6.9 14.2 0.9 103.0 5.5 0.3 0.7 3.2 0.2 0.9 0.5 6.1 0.0 1.0 0.0 0.8 0.1 0.1 0.0 0.2 0.2 0.0 0.1 1.5 0.0 5.7 3.2 0.0 2.1 0.0 0.9 0.3 0.1 4.1 0.1 0.7 0.7 0.2 0.0 0.0 0.6 0.2 0.0 0.3 0.0 0.4 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.2 0.7 1.2 2.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 5.4 0.1 0.1 2.2 0.3 1.7 1.1 0.0 0.1 0.2 0.3 1.5 2.0 0.1 0.2 0.6 171.1 0.4 1.5 0.3 0.1 0.1 0.2 0.4 0.0 0.0 0.2 426.7 0.5 1.8 0.0 0.1 1.1 1.5 3.4 6.3 3.9 1.8 7.3 8.8 6.2 7.4 6.9 5.5 6.1 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 1.2 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 10.1 0.3 0.0 0.0 0.0 205.8 0.0 0.0 1.4 0.0 8.6 0.7 0.0 1.4 0.3 0.0 0.0 0.0 0.0 0.4 0.0 2.6 0.0 1.4 0.0 0.0 0.3 0.0 1499.6 7.8 0.6 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 11.2 4.5 0.0 0.0 237.6 0.1 0.0 0.1 0.1 PKD2L1 "PCL, PKD2L, PKDL, TRPP3" ENSG00000107593 "Polycystin 2 like 1, transient receptor potential cation channel" Q9P0L9 10 100288149-100330264 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.8;lymphoid tissue: 7.9;retina: 13.3" "Cell type enhanced" "Detected in some" "Early spermatids: 14.6;Hofbauer cells: 13.6;Horizontal cells: 60.6;Kupffer cells: 14.4;Late spermatids: 20.1" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB022621, HPA070002" Uncertain Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Actin filaments, Cytosol" "CAB022621: , HPA070002: " "unprognostic (2.67e-1)" "unprognostic (3.66e-7)" "unprognostic (8.07e-3)" "unprognostic (4.38e-2)" "unprognostic (4.70e-2)" "unprognostic (5.31e-2)" "unprognostic (2.19e-1)" "unprognostic (2.85e-2)" "unprognostic (2.01e-1)" "unprognostic (9.25e-2)" "unprognostic (1.55e-1)" "unprognostic (9.37e-2)" "unprognostic (1.49e-4)" "unprognostic (3.00e-1)" "unprognostic (2.05e-2)" "unprognostic (7.94e-2)" "unprognostic (2.25e-1)" 0.2 0.1 5.4 0.4 5.6 0.9 0.7 4.8 10.8 0.1 4.8 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.4 4.9 0.3 1.6 2.3 1.5 4.9 5.2 0.1 0.1 0.0 0.1 0.5 5.1 0.3 1.2 13.3 0.1 0.0 0.1 0.0 0.6 0.0 5.0 7.9 0.0 2.3 5.0 0.9 0.0 0.0 1.7 0.2 0.0 5.5 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.1 5.4 5.6 4.8 10.8 5.4 4.9 4.9 5.2 5.1 5.0 5.0 5.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 14.6 0.0 0.0 0.1 0.0 0.0 2.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 13.6 60.6 0.4 0.0 0.0 14.4 0.0 20.1 0.3 3.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 PLAT ENSG00000104368 "Plasminogen activator, tissue type" P00750 8 42174718-42207709 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Plasminogen activation" "Hydrolase, Protease, Serine protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 246.0;urinary bladder: 181.4" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 763.3;Urothelial cells: 992.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 604.7;HMC-1: 425.2;hTERT-RPE1: 344.9;LHCN-M2: 298.2;U-2197: 441.2;WM-115: 806.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003412, CAB009335" Supported Approved "Actin filaments" "Secreted to blood" NA NA 9900000 110000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 17: WM-115 - Nervous system development" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments" "CAB009335: AB_2237146, HPA003412: AB_1858205" "prognostic favorable (7.57e-4)" "unprognostic (2.23e-1)" "unprognostic (4.08e-1)" "unprognostic (3.39e-1)" "unprognostic (4.88e-3)" "unprognostic (9.39e-2)" "unprognostic (4.65e-3)" "unprognostic (5.78e-2)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (2.98e-3)" "unprognostic (2.46e-1)" "prognostic unfavorable (4.95e-4)" "unprognostic (8.72e-3)" "unprognostic (1.37e-2)" "unprognostic (2.63e-2)" "unprognostic (6.09e-2)" 58.9 44.0 14.0 35.6 13.7 0.1 35.1 14.6 17.4 21.8 10.3 55.3 29.9 49.6 16.8 33.7 49.8 40.4 19.3 12.5 16.6 91.9 5.3 41.3 2.3 15.4 15.4 21.5 16.0 246.0 13.3 44.4 16.6 54.0 25.0 2.1 15.6 29.1 8.8 6.2 34.6 32.9 16.0 2.0 41.8 11.9 18.8 4.4 30.9 9.8 2.7 181.4 33.1 14.0 4.2 1.4 29.0 9.1 43.1 61.9 0.9 125.8 216.4 54.2 43.4 1.4 604.7 0.0 4.4 17.1 28.4 14.5 0.3 23.9 78.5 64.6 8.4 0.7 1.0 0.6 253.9 0.2 425.2 65.6 0.4 140.3 6.0 344.9 103.9 0.2 4.6 0.8 298.2 0.0 0.6 0.5 42.3 0.3 48.2 0.2 103.5 0.3 12.6 0.4 0.3 7.4 0.2 0.4 158.7 39.7 1.0 0.3 189.3 11.6 43.1 441.2 15.6 0.2 1.1 0.2 9.7 0.2 806.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 14.0 13.7 14.6 17.4 12.5 16.6 15.4 15.4 16.6 16.0 18.8 14.0 63.5 0.0 13.7 0.0 2.9 10.8 763.3 155.9 7.4 4.7 103.9 66.3 7.4 1.5 19.1 0.0 4.2 0.6 0.9 0.1 0.0 9.3 0.9 4.8 104.2 98.2 0.0 0.0 1.6 0.6 1.3 136.5 2.0 5.1 164.0 89.7 36.4 0.8 1.9 1.7 4.0 0.0 4.1 1.0 17.7 1.5 3.7 4.7 23.2 25.3 1.6 2.1 1.0 42.7 0.3 52.0 0.0 2.6 2.8 193.3 0.2 0.3 4.0 3.8 13.1 10.8 48.3 1.1 0.6 13.6 13.5 0.7 6.0 0.5 0.5 992.1 POU6F1 "BRN5, MPOU, TCFB1" ENSG00000184271 "POU class 6 homeobox 1" 12 51186936-51217708 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 20.9;Excitatory neurons: 22.2;Inhibitory neurons: 29.4;Oligodendrocyte precursor cells: 21.1;Oligodendrocytes: 23.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 6.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 4.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047021, HPA050411" Enhanced Supported "Nuclear bodies,Actin filaments" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear bodies" "Actin filaments" "HPA047021: AB_2679905, HPA050411: AB_2681119" "unprognostic (4.96e-2)" "unprognostic (1.08e-1)" "unprognostic (1.48e-3)" "unprognostic (1.45e-2)" "unprognostic (2.72e-1)" "unprognostic (6.58e-2)" "unprognostic (9.70e-2)" "unprognostic (7.11e-3)" "unprognostic (4.45e-1)" "unprognostic (2.05e-1)" "prognostic favorable (6.61e-4)" "unprognostic (2.48e-2)" "unprognostic (9.36e-2)" "unprognostic (2.09e-3)" "unprognostic (1.74e-1)" "unprognostic (2.02e-1)" "unprognostic (2.33e-1)" 2.0 1.5 0.3 1.2 1.3 0.4 1.7 3.6 6.0 3.1 0.0 2.4 0.6 2.5 0.1 0.7 2.2 1.2 1.1 1.4 0.0 1.2 0.5 1.8 0.8 0.0 0.0 3.2 1.3 0.8 2.6 0.6 0.0 2.1 0.2 1.3 2.1 1.4 4.0 1.4 1.5 1.5 0.0 1.5 1.3 0.3 0.3 0.2 2.3 1.3 0.5 1.7 1.7 0.0 0.3 0.8 1.0 1.4 0.3 1.2 0.5 0.5 0.6 0.6 0.7 0.1 0.5 1.8 0.2 0.4 0.3 0.0 1.2 0.0 0.0 2.8 1.8 0.5 1.1 0.0 1.0 0.4 2.4 0.6 0.5 1.0 0.1 1.4 2.0 0.7 0.7 4.9 0.3 0.0 0.2 0.7 1.8 0.0 0.0 0.5 0.6 0.0 0.3 0.0 1.3 2.2 1.2 0.0 2.3 0.5 0.5 1.7 1.5 1.1 0.9 0.3 1.3 3.2 2.8 0.2 1.0 0.4 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 3.6 6.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 4.5 6.4 2.8 20.9 2.1 3.1 1.3 0.4 0.0 10.0 2.3 1.3 3.1 1.5 1.7 7.3 4.2 0.6 1.1 0.1 1.9 0.8 5.3 0.9 1.7 4.8 0.0 2.7 22.2 2.0 0.2 3.2 0.5 1.6 5.1 2.4 3.6 1.2 0.3 1.7 29.4 0.3 4.1 2.2 3.9 3.7 5.9 1.1 1.8 8.4 1.7 3.7 0.0 21.1 23.6 1.6 0.2 6.8 0.7 1.8 0.0 0.7 2.7 7.9 0.0 3.8 4.1 0.1 0.7 0.5 2.8 0.4 1.8 0.2 0.6 0.7 PPP1R12A "M130, MBS, MYPT1" ENSG00000058272 "Protein phosphatase 1 regulatory subunit 12A" O14974 12 79773563-79935460 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 353.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041296, HPA071956" Approved Supported "Actin filaments,Cytosol" NA NA 270000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Actin filaments, Cytosol" "HPA041296: AB_2677394, HPA071956: AB_2732192" "unprognostic (3.34e-1)" "unprognostic (1.73e-1)" "unprognostic (2.54e-1)" "unprognostic (1.72e-1)" "unprognostic (5.60e-3)" "unprognostic (6.19e-2)" "prognostic unfavorable (1.72e-4)" "unprognostic (1.61e-1)" "unprognostic (9.69e-3)" "unprognostic (1.85e-1)" "unprognostic (2.04e-2)" "unprognostic (1.04e-1)" "unprognostic (2.44e-3)" "unprognostic (5.50e-2)" "unprognostic (1.95e-1)" "unprognostic (2.45e-1)" "unprognostic (1.38e-1)" 31.5 18.6 21.2 32.3 26.6 57.5 21.7 25.3 65.3 34.1 15.0 73.3 22.8 66.2 31.1 71.2 40.9 36.6 28.0 27.7 20.3 18.2 14.2 24.6 31.9 14.3 14.5 27.4 11.0 18.5 11.2 41.6 14.2 67.6 35.4 14.6 19.0 84.8 20.5 17.6 27.6 83.7 14.1 30.8 29.2 23.5 20.7 34.3 24.9 27.2 27.8 64.5 27.7 27.0 42.9 36.5 49.3 28.5 36.8 36.2 45.8 84.0 46.5 53.1 35.2 34.9 20.7 36.9 33.4 113.8 21.4 33.4 38.6 32.9 63.8 51.3 24.3 98.2 40.5 24.1 29.1 64.8 59.5 30.7 24.3 53.6 49.1 60.1 37.2 36.7 41.1 43.0 57.0 27.7 71.4 34.3 39.1 18.8 25.2 57.9 54.4 27.8 31.4 66.6 23.8 17.9 66.3 23.2 28.5 45.1 32.4 30.9 56.8 56.3 29.9 40.1 48.2 28.3 27.8 48.6 19.2 36.3 49.3 155.1 44.4 197.4 62.8 47.5 56.5 56.8 59.7 66.8 41.8 52.8 47.3 61.3 187.2 98.2 70.4 35.3 69.6 46.3 21.2 26.6 25.3 65.3 27.7 20.3 14.3 14.5 14.2 14.1 20.7 27.0 108.4 76.9 65.9 168.5 79.7 84.5 69.0 59.1 57.5 82.2 30.7 69.0 127.4 32.9 61.5 53.3 35.5 66.7 113.4 44.9 15.6 50.9 111.3 47.5 113.6 93.6 44.9 66.3 240.4 40.0 82.0 82.4 42.8 81.2 121.4 66.6 55.0 27.5 78.0 102.6 135.4 37.7 44.7 57.5 100.8 64.2 86.3 92.8 60.5 132.1 112.0 52.2 120.5 353.9 132.9 55.9 42.7 147.4 60.7 52.0 34.3 26.3 41.0 61.4 210.4 74.6 332.7 133.4 89.8 50.9 81.1 83.7 119.7 81.5 41.3 63.6 PPP1R12B "MGC131980, MGC87886, MYPT2, PP1bp55" ENSG00000077157 "Protein phosphatase 1 regulatory subunit 12B" O60237 1 202348699-202592706 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 356.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 836.8;Excitatory neurons: 225.7;Granulosa cells: 438.3;Oligodendrocytes: 647.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 16.2" "Lineage enriched" "Detected in many" 7 "granulocytes: 16.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024171, HPA024640" Enhanced Approved "Plasma membrane,Actin filaments" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Actin filaments" "HPA024171: AB_1854266, HPA024640: AB_1854265" "unprognostic (5.24e-2)" "unprognostic (8.59e-2)" "unprognostic (1.38e-1)" "unprognostic (2.75e-2)" "unprognostic (3.04e-1)" "unprognostic (5.45e-3)" "unprognostic (3.12e-2)" "unprognostic (9.13e-3)" "unprognostic (4.05e-2)" "unprognostic (3.74e-2)" "unprognostic (2.79e-2)" "unprognostic (1.80e-1)" "unprognostic (3.60e-3)" "unprognostic (6.98e-3)" "unprognostic (1.27e-1)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" 40.0 11.1 5.1 36.0 12.6 8.3 17.8 8.9 9.9 51.8 15.5 151.0 24.1 222.0 30.5 150.1 52.6 72.5 356.9 5.5 6.5 14.3 8.4 24.8 18.6 17.2 15.3 38.3 7.2 6.2 5.0 34.4 18.0 142.8 64.8 7.6 20.0 198.6 84.1 11.0 30.9 246.4 16.2 30.8 41.5 7.1 9.2 7.7 10.9 80.5 15.1 86.7 23.0 27.3 2.2 4.4 3.3 3.2 4.6 3.3 5.4 1.7 1.7 1.8 1.7 1.9 3.9 2.5 0.8 3.2 4.3 7.0 5.0 2.7 1.9 3.3 3.1 2.5 7.1 1.2 1.1 5.4 2.8 2.6 3.0 2.5 2.6 9.1 1.5 2.8 3.9 2.9 3.1 1.7 4.1 3.4 2.3 2.4 0.9 2.6 8.5 3.7 1.4 8.1 4.0 3.1 3.3 3.9 1.9 4.4 3.4 2.4 1.9 2.5 1.5 1.9 1.5 4.2 4.3 2.7 2.4 4.4 10.2 2.4 1.7 1.5 1.6 1.0 1.4 2.0 1.1 1.0 1.5 2.1 1.3 1.0 16.2 0.7 1.5 1.7 1.7 0.5 5.1 12.6 8.9 9.9 5.5 6.5 17.2 15.3 18.0 16.2 9.2 27.3 12.5 12.8 19.8 181.5 6.0 17.3 49.0 35.6 8.6 59.3 11.1 20.6 836.8 11.5 23.0 12.9 75.0 18.1 8.6 52.9 11.7 10.1 39.2 19.3 16.1 15.2 24.0 5.2 225.7 12.9 8.4 51.4 17.3 7.6 18.9 438.3 16.4 9.6 9.4 26.9 205.0 17.2 63.1 23.5 10.9 13.1 12.2 8.2 8.8 102.1 7.8 10.2 5.2 102.5 647.4 6.3 21.1 51.1 9.6 24.3 12.8 7.1 27.4 30.4 32.9 38.6 162.7 19.3 13.9 7.1 10.9 25.4 10.7 14.2 33.9 28.4 PRKRIP1 "C114, FLJ13902, KRBOX3" ENSG00000128563 "PRKR interacting protein 1" Q9H875 7 102363872-102426676 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051146 Uncertain Supported "Actin filaments,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Actin filaments" Cytosol "HPA051146: AB_2681361" "unprognostic (4.78e-3)" "unprognostic (7.23e-3)" "prognostic unfavorable (3.65e-4)" "unprognostic (8.25e-2)" "unprognostic (2.99e-3)" "unprognostic (3.15e-2)" "unprognostic (1.99e-2)" "unprognostic (4.38e-3)" "unprognostic (1.57e-3)" "unprognostic (1.50e-2)" "unprognostic (2.61e-3)" "unprognostic (9.79e-3)" "prognostic unfavorable (4.39e-4)" "unprognostic (1.82e-1)" "unprognostic (1.01e-1)" "unprognostic (4.88e-1)" "prognostic favorable (1.94e-4)" 12.6 16.2 15.1 7.2 15.2 16.5 12.8 18.4 17.9 15.4 14.3 14.1 8.6 13.7 3.5 11.7 14.2 5.7 10.1 15.1 17.0 16.1 12.1 9.7 12.5 16.0 15.4 14.7 11.6 11.6 15.4 7.0 15.5 15.5 3.7 4.2 12.1 6.8 12.2 18.6 12.4 5.0 14.8 18.3 13.5 19.0 15.4 12.1 14.5 7.4 7.7 13.6 13.1 16.0 17.0 12.4 11.8 17.3 5.4 7.7 17.6 13.1 9.0 21.1 17.8 20.3 14.7 17.6 20.3 11.2 15.0 19.2 9.0 12.9 10.7 20.1 19.1 7.3 12.3 11.9 13.3 10.3 10.3 5.5 12.4 16.2 10.9 11.3 10.7 19.9 21.1 26.3 13.1 33.7 34.4 46.7 18.3 15.1 14.7 24.8 11.5 27.5 11.3 7.2 13.5 25.9 19.5 29.2 20.1 11.8 15.1 20.0 12.7 21.6 26.0 23.3 20.5 36.0 26.7 31.6 18.3 18.4 29.4 3.8 10.1 18.3 11.5 10.0 10.7 14.0 11.5 12.9 7.8 13.0 14.2 12.4 20.7 12.9 13.6 14.1 9.6 10.0 15.1 15.2 18.4 17.9 15.1 17.0 16.0 15.4 15.5 14.8 15.4 16.0 23.4 32.1 21.8 0.0 31.4 13.4 19.0 14.8 20.5 23.1 21.1 19.3 23.8 14.3 23.0 16.5 31.3 27.5 31.7 13.7 31.3 24.8 77.8 29.6 26.0 21.4 16.3 21.8 0.0 25.1 26.7 21.3 16.3 32.0 22.8 27.1 15.0 14.1 27.6 23.5 0.0 13.8 8.2 13.8 16.9 92.5 17.1 19.2 12.4 0.0 22.1 25.3 20.6 0.0 0.0 29.5 9.8 16.6 28.6 22.4 14.6 26.6 27.1 21.5 32.9 29.2 27.0 88.4 47.6 20.8 17.6 41.9 30.4 24.2 12.0 19.4 PRSS12 "BSSP-3, MRT1" ENSG00000164099 "Serine protease 12" P56730 4 118280038-118353003 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Club cells: 34.3;Cytotrophoblasts: 48.0;Respiratory ciliated cells: 76.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 70.2;SH-SY5Y: 215.4;THP-1: 100.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035054 Uncertain Approved "Nucleoplasm,Actin filaments" "Secreted - unknown location" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" "Actin filaments" Nucleoplasm "HPA035054: AB_10603990" "unprognostic (4.30e-2)" "unprognostic (1.04e-2)" "unprognostic (2.55e-1)" "unprognostic (4.41e-2)" "prognostic favorable (2.66e-4)" "prognostic favorable (1.03e-4)" "unprognostic (4.21e-1)" "unprognostic (3.48e-2)" "unprognostic (7.83e-2)" "unprognostic (6.38e-2)" "unprognostic (1.09e-1)" "unprognostic (1.27e-1)" "unprognostic (2.41e-2)" "unprognostic (1.29e-1)" "unprognostic (1.85e-1)" "unprognostic (9.55e-2)" "unprognostic (1.09e-1)" 0.6 0.5 1.4 1.6 0.9 0.1 2.2 0.6 1.3 14.5 14.4 6.7 2.7 1.9 0.6 3.2 10.5 9.8 0.0 2.7 0.5 0.8 0.6 7.6 0.1 0.5 1.9 1.6 7.7 0.1 0.6 10.6 0.7 1.4 6.4 0.3 2.5 2.0 0.2 5.9 4.8 1.3 0.5 0.0 9.2 10.0 1.2 1.0 0.2 1.2 5.7 3.8 12.6 0.5 5.2 0.2 1.8 0.0 0.2 13.3 0.1 46.0 41.5 9.7 16.1 0.1 18.7 0.0 0.2 70.2 4.9 0.8 31.1 9.5 12.7 0.2 7.2 0.0 3.6 0.0 1.4 0.0 0.2 4.1 17.5 3.4 9.9 31.2 0.1 0.6 0.0 0.0 8.0 0.3 0.5 9.6 2.2 36.4 2.9 0.0 38.7 0.0 0.0 7.0 5.1 215.4 0.0 0.2 3.0 30.9 0.0 100.6 0.0 19.2 2.8 12.2 9.1 1.0 0.1 0.0 1.0 3.3 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.9 0.6 1.3 2.7 0.5 0.5 1.9 0.7 0.5 1.2 0.5 0.3 6.4 4.6 0.7 0.2 8.4 0.8 16.4 2.2 0.6 0.8 0.8 1.4 10.0 34.3 1.8 0.0 48.0 0.0 26.8 0.0 0.4 9.9 19.7 16.8 0.9 5.3 0.0 10.5 10.2 4.5 7.1 17.9 2.6 7.0 3.3 0.0 0.4 3.8 0.0 14.3 2.7 10.2 0.0 4.2 18.3 0.0 0.4 5.4 7.5 0.0 0.0 0.0 0.5 0.2 8.1 12.8 0.0 0.2 0.4 9.4 0.6 76.1 0.2 0.0 0.6 4.9 10.1 13.3 3.6 4.3 11.9 0.7 21.8 5.3 4.7 PSMD1 "P112, Rpn2, S1" ENSG00000173692 "Proteasome 26S subunit, non-ATPase 1" Q99460 2 231056845-231173116 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 247.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021092, HPA036736, HPA036737" Enhanced Approved "Nucleoplasm,Actin filaments" NA NA 230000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Actin filaments" "CAB021092: AB_10123242, HPA036736: AB_2675278, HPA036737: AB_2675279" "unprognostic (9.32e-3)" "unprognostic (2.08e-2)" "unprognostic (1.07e-1)" "unprognostic (3.81e-2)" "unprognostic (2.71e-1)" "unprognostic (1.78e-2)" "prognostic unfavorable (8.63e-12)" "prognostic unfavorable (2.34e-4)" "unprognostic (2.57e-1)" "unprognostic (1.72e-2)" "unprognostic (3.09e-3)" "unprognostic (2.49e-1)" "unprognostic (8.91e-3)" "unprognostic (1.10e-2)" "unprognostic (6.26e-2)" "unprognostic (4.16e-2)" "unprognostic (1.70e-3)" 37.3 38.2 21.9 31.7 26.1 20.1 29.0 21.9 33.7 26.3 20.9 34.8 35.5 37.4 25.6 41.5 24.3 20.3 51.3 27.5 28.5 34.1 42.1 27.0 28.8 26.9 24.9 19.2 17.3 72.7 32.9 36.8 28.3 29.7 36.8 25.4 25.8 33.4 136.3 34.9 29.3 44.9 24.5 25.2 27.9 29.0 24.5 36.6 27.4 81.6 38.3 37.3 27.8 24.4 103.9 113.1 120.6 93.8 122.2 88.7 115.4 135.3 139.4 133.4 134.0 136.5 97.6 80.0 123.3 150.5 138.0 95.0 169.4 125.0 174.3 124.3 93.3 148.7 81.6 155.5 62.9 133.3 119.4 76.5 57.8 142.4 73.9 73.4 159.6 70.3 212.1 56.8 158.7 100.3 103.0 68.3 157.8 100.1 89.3 86.0 190.4 77.7 96.5 104.0 78.8 74.1 108.7 94.1 65.7 120.6 75.3 74.7 152.3 101.4 110.8 126.0 129.8 48.6 80.2 140.4 162.7 100.0 123.4 34.6 27.8 18.8 25.1 39.0 27.3 21.0 25.8 23.8 30.9 17.2 19.2 22.9 12.5 35.9 42.5 18.9 32.3 25.7 21.9 26.1 21.9 33.7 27.5 28.5 26.9 24.9 28.3 24.5 24.5 24.4 51.9 51.3 48.5 77.7 32.9 33.1 37.7 57.0 19.9 46.4 23.0 25.8 125.4 31.5 53.0 33.1 41.7 119.2 27.0 63.6 17.6 83.9 6.2 51.2 67.5 51.7 39.4 61.6 100.0 102.2 101.4 54.6 42.3 60.9 103.9 67.8 30.0 86.9 72.3 90.9 96.0 30.0 57.0 44.2 23.5 9.9 34.8 49.8 17.8 54.4 62.6 46.6 29.9 67.3 93.1 98.6 26.2 45.9 49.4 46.5 46.9 32.1 66.9 53.2 72.3 54.6 128.2 247.9 158.8 39.2 33.1 167.5 36.6 65.5 42.9 38.8 PSTK "C10orf89, MGC35392" ENSG00000179988 "Phosphoseryl-tRNA kinase" Q8IV42 10 122954381-122997513 "Enzymes, Predicted intracellular proteins" "Protein biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 31.3;Spermatocytes: 37.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037780, HPA037781" Approved Approved "Nucleoli,Nuclear bodies,Actin filaments" No No "Cluster 24: B-cells - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "Actin filaments" "Nucleoli, Nuclear bodies" "HPA037780: AB_2675662, HPA037781: AB_10670530" "unprognostic (8.95e-3)" "unprognostic (5.51e-3)" "unprognostic (1.37e-1)" "unprognostic (7.39e-4)" "unprognostic (5.21e-2)" "unprognostic (4.08e-3)" "unprognostic (1.60e-2)" "unprognostic (5.92e-4)" "unprognostic (3.55e-2)" "unprognostic (1.16e-1)" "unprognostic (6.22e-3)" "unprognostic (7.10e-3)" "unprognostic (2.39e-1)" "unprognostic (4.50e-2)" "unprognostic (4.92e-2)" "unprognostic (3.02e-2)" "unprognostic (5.55e-4)" 0.9 2.2 1.3 0.6 1.5 6.1 2.9 1.5 2.2 1.9 0.3 1.6 1.9 1.9 3.5 1.5 1.9 0.7 1.7 1.5 1.6 2.0 4.1 1.0 0.9 1.6 1.5 1.3 2.1 1.1 2.6 1.3 2.5 2.0 1.5 0.5 1.9 1.1 3.5 1.6 1.0 1.9 1.3 1.1 1.3 3.2 1.4 1.8 2.4 0.9 1.2 1.3 1.3 2.8 4.1 3.4 1.7 0.8 1.6 3.2 2.1 2.0 3.5 3.0 3.7 4.6 3.4 4.4 3.9 2.5 2.0 2.3 0.7 3.1 3.4 2.4 8.7 2.7 1.2 4.0 4.3 6.7 3.6 3.3 5.2 2.9 5.2 2.7 2.3 3.9 4.3 6.0 4.3 6.6 2.0 3.9 3.3 1.6 4.3 4.5 3.0 4.4 4.3 2.6 1.6 2.1 3.9 3.8 5.3 1.4 1.8 0.4 3.1 2.8 2.6 1.2 4.5 2.6 1.6 5.8 2.4 4.3 0.9 0.0 5.0 6.0 7.4 3.1 8.8 6.2 5.7 7.0 6.7 5.9 7.5 7.7 0.6 6.8 3.6 6.7 3.8 5.3 1.3 1.5 1.5 2.2 1.5 1.6 1.6 1.5 2.5 1.3 1.4 2.8 3.0 9.6 7.3 14.4 4.6 4.5 5.0 11.0 5.2 8.3 7.1 11.7 5.9 10.0 7.5 5.5 8.4 7.7 8.0 1.6 9.8 4.6 31.3 5.7 5.2 3.2 4.2 3.4 18.8 6.3 3.1 6.0 1.5 11.6 2.5 8.1 3.6 6.3 4.8 5.0 20.3 2.6 14.2 2.1 4.3 5.4 5.3 3.0 5.4 4.7 6.1 8.8 5.2 12.5 29.4 3.7 3.8 5.7 3.3 3.5 3.0 7.7 8.3 11.4 0.0 5.6 8.6 37.5 20.6 5.5 4.7 9.6 6.9 10.8 4.3 3.5 PTPN11 "BPTP3, NS1, PTP2C, SH-PTP2, SHP-2, SHP2" ENSG00000179295 "Protein tyrosine phosphatase non-receptor type 11" Q06124 12 112418351-112509918 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005377 Approved Supported "Nucleoplasm,Nucleoli rim,Actin filaments,Cytosol" NA NA 74000 "Cluster 6: Non-specific - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Nucleoli rim" "Actin filaments, Cytosol" "CAB005377: AB_632401" "unprognostic (2.18e-3)" "unprognostic (1.73e-3)" "unprognostic (5.62e-2)" "unprognostic (1.19e-1)" "unprognostic (1.63e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "unprognostic (4.25e-2)" "unprognostic (3.55e-2)" "unprognostic (1.88e-1)" "unprognostic (2.22e-2)" "unprognostic (8.85e-2)" "unprognostic (3.75e-3)" "unprognostic (1.66e-1)" "unprognostic (2.46e-1)" "unprognostic (3.62e-2)" "unprognostic (1.80e-2)" 62.9 36.6 74.6 34.7 91.7 46.3 37.6 72.7 115.7 37.9 38.4 32.5 27.6 37.8 28.7 38.9 24.3 29.4 68.7 66.1 85.6 39.7 53.0 34.4 35.6 79.0 84.1 26.2 31.6 53.4 16.1 38.0 85.7 35.2 30.6 51.8 25.9 42.4 75.1 32.1 26.1 45.7 83.4 26.7 30.4 18.2 81.7 35.5 46.8 64.0 32.5 40.1 23.5 106.3 116.9 107.6 77.0 73.4 109.7 106.1 92.7 136.4 148.2 105.5 78.5 107.7 43.4 124.5 69.4 127.4 66.7 68.1 100.1 121.6 173.8 93.1 85.0 181.5 102.6 59.8 109.2 145.8 108.0 86.6 119.6 113.6 159.8 101.3 88.7 92.0 140.2 41.3 103.3 83.2 101.0 69.7 94.1 112.3 73.4 102.4 114.6 70.5 97.3 126.7 53.3 66.1 133.7 99.8 85.2 77.6 114.8 97.8 108.1 122.9 110.0 74.2 121.8 79.4 141.6 120.2 102.2 99.7 117.7 32.2 11.7 16.8 14.8 10.2 14.0 18.1 13.3 12.4 13.6 20.8 15.3 11.9 10.7 12.6 13.7 18.3 10.9 7.2 74.6 91.7 72.7 115.7 66.1 85.6 79.0 84.1 85.7 83.4 81.7 106.3 49.0 60.9 68.2 27.7 25.8 25.6 39.9 25.3 20.5 29.9 40.5 32.4 131.6 24.3 41.8 36.8 16.7 23.5 34.2 25.4 33.2 37.5 63.1 31.3 92.6 46.2 13.1 21.7 67.6 42.8 25.3 35.8 21.9 40.9 28.4 33.1 26.0 101.5 26.8 13.5 54.7 22.0 18.3 33.3 21.6 28.5 51.6 31.8 14.2 40.3 31.1 59.8 29.9 32.6 73.0 59.3 19.6 79.7 37.0 73.4 16.6 39.8 23.5 22.2 32.9 58.2 49.2 7.1 6.6 37.5 27.4 35.2 31.7 30.5 22.2 66.8 RAI14 "DKFZp564G013, KIAA1334, NORPEG, RAI13" ENSG00000039560 "Retinoic acid induced 14" Q9P0K7 5 34656328-34832612 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 208.2;Early spermatids: 210.1;Late spermatids: 364.3;Syncytiotrophoblasts: 156.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 267.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 23.8" "HPA036949, HPA036950" Supported Supported "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm "Actin filaments, Cytosol" "HPA036949: AB_10670568, HPA036950: AB_10669721" "unprognostic (7.63e-2)" "unprognostic (9.86e-2)" "unprognostic (4.87e-2)" "unprognostic (1.40e-1)" "unprognostic (3.38e-2)" "unprognostic (4.75e-2)" "unprognostic (5.49e-2)" "unprognostic (6.18e-2)" "unprognostic (6.28e-2)" "unprognostic (2.62e-1)" "unprognostic (8.18e-2)" "unprognostic (4.58e-2)" "prognostic unfavorable (9.75e-4)" "prognostic unfavorable (2.05e-4)" "unprognostic (1.33e-1)" "unprognostic (4.81e-2)" "unprognostic (4.34e-2)" 10.6 9.0 10.1 21.6 14.5 2.4 9.8 13.3 9.8 51.2 17.5 22.1 7.0 53.6 6.2 10.0 13.8 18.7 6.8 8.0 9.4 18.9 27.5 26.2 14.7 18.1 13.9 9.5 7.9 10.8 4.9 34.6 17.1 11.4 10.3 10.2 16.5 25.4 1.9 19.5 7.5 58.0 15.6 39.4 10.8 39.2 12.7 6.3 10.1 2.3 10.2 43.0 14.3 20.0 12.5 48.5 55.2 37.1 29.0 100.9 70.3 147.0 118.3 83.3 83.0 36.7 15.6 2.9 57.0 72.5 90.5 8.2 64.0 109.0 179.2 0.2 30.5 20.6 43.3 22.9 90.0 0.5 1.9 94.8 34.0 149.4 118.1 136.7 267.4 4.6 29.4 1.0 110.1 10.0 2.3 0.7 43.3 7.8 47.0 18.2 84.1 0.6 97.4 70.1 14.4 7.9 86.8 12.8 39.5 80.5 14.9 2.3 173.2 134.1 71.7 33.5 65.1 3.1 0.1 0.4 113.5 0.4 53.5 0.9 0.2 0.1 0.9 0.0 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.4 0.8 0.0 0.1 0.0 0.0 10.1 14.5 13.3 9.8 8.0 9.4 18.1 13.9 17.1 15.6 12.7 20.0 16.2 105.8 208.2 33.3 0.9 12.0 32.2 46.7 23.9 3.2 27.8 9.9 5.2 7.2 81.8 35.0 68.8 32.3 0.6 17.9 7.9 36.1 210.1 35.7 36.1 96.1 1.8 2.7 6.6 28.5 75.3 25.0 11.2 36.1 3.8 22.7 17.2 23.0 7.2 15.2 6.0 1.1 16.2 1.6 4.3 364.3 72.1 4.6 5.4 15.0 1.0 19.3 0.0 31.2 60.1 53.3 5.1 31.6 0.1 26.6 6.3 25.3 24.8 5.1 0.0 6.0 33.4 9.0 9.2 6.4 15.8 156.1 3.4 11.4 2.6 61.5 RARA "NR1B1, RAR" ENSG00000131759 "Retinoic acid receptor alpha" P10276 17 40309180-40357643 "Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 52.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 221.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058282, HPA071548" Supported "Nucleoplasm,Nucleoli,Actin filaments,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Nucleoli, Actin filaments, Cytosol" "HPA058282: AB_2683666, HPA071548: " "unprognostic (8.05e-3)" "unprognostic (1.89e-1)" "unprognostic (9.48e-3)" "prognostic favorable (2.60e-4)" "unprognostic (8.67e-3)" "unprognostic (4.87e-3)" "unprognostic (2.77e-1)" "unprognostic (5.73e-2)" "unprognostic (1.45e-1)" "unprognostic (3.54e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (2.29e-3)" "unprognostic (1.59e-2)" "unprognostic (5.60e-2)" "unprognostic (1.60e-1)" "unprognostic (1.09e-2)" 47.6 21.1 3.2 28.3 4.4 59.6 37.2 7.2 16.5 43.7 5.1 31.0 28.4 32.2 10.7 14.9 40.7 41.3 40.8 7.0 5.7 24.1 42.3 58.4 16.4 5.3 2.7 40.8 14.7 11.3 30.6 25.7 2.8 29.8 13.2 18.3 20.6 21.3 62.6 24.8 32.2 28.6 1.8 41.7 22.9 28.8 4.9 10.0 26.9 17.4 11.8 30.3 30.2 4.3 18.0 41.9 11.8 20.5 23.4 35.9 12.5 14.9 21.8 21.5 13.6 28.6 15.1 9.6 22.7 33.2 18.9 51.1 14.2 33.9 12.0 77.5 21.4 26.6 21.2 29.8 37.0 9.4 81.3 48.2 10.0 22.7 29.2 75.8 30.9 8.4 17.6 20.2 23.7 221.5 6.4 34.2 10.7 16.2 13.3 12.9 71.3 37.0 12.2 14.4 5.4 40.5 31.0 124.8 42.1 11.7 119.1 36.6 35.8 25.3 45.3 44.2 15.4 48.7 16.9 8.3 38.4 18.7 77.1 26.3 8.9 34.6 3.2 14.6 5.1 2.0 3.6 3.8 12.4 1.7 1.5 2.8 52.6 5.9 19.5 3.8 3.1 5.0 3.2 4.4 7.2 16.5 7.0 5.7 5.3 2.7 2.8 1.8 4.9 4.3 35.6 3.2 7.0 2.3 43.4 19.5 25.6 8.4 18.8 23.2 35.4 17.5 3.8 10.0 5.5 7.3 6.2 2.2 36.9 41.2 13.7 16.7 60.5 20.7 22.0 28.4 9.6 5.7 5.4 19.2 5.8 28.5 10.7 18.4 35.5 13.9 26.0 28.8 12.3 3.3 2.6 13.1 6.1 45.4 65.5 66.2 41.7 56.9 28.4 2.8 26.1 11.8 6.2 4.0 0.3 22.0 33.1 23.0 21.0 13.4 70.9 17.7 4.9 10.2 32.9 42.1 26.7 3.6 7.6 7.1 18.9 5.2 31.7 6.5 16.5 19.3 RFLNB "Cfm1, FAM101B, MGC45871, RefilinB" ENSG00000183688 "Refilin B" Q8N5W9 17 439978-445939 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 77.9" "Cell type enhanced" "Detected in many" "Adipocytes: 101.3;Endothelial cells: 51.1;Hofbauer cells: 38.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 201.5" "Lineage enriched" "Detected in many" 21 "granulocytes: 201.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 95.5;HMC-1: 222.1;NB-4: 74.8;U-937: 64.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030879, HPA060388" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Actin filaments" "Plasma membrane, Cytosol" "HPA030879: AB_2673643, HPA060388: AB_2732649" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (2.87e-1)" "unprognostic (3.14e-1)" "unprognostic (3.52e-2)" "unprognostic (2.34e-1)" "unprognostic (1.31e-1)" "unprognostic (1.48e-1)" "unprognostic (1.94e-1)" "unprognostic (2.87e-2)" "unprognostic (2.48e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (1.54e-4)" "unprognostic (3.45e-2)" "unprognostic (9.22e-2)" "unprognostic (1.43e-1)" "unprognostic (9.03e-3)" 19.8 5.9 2.4 7.4 2.5 77.9 15.6 2.3 2.8 8.7 10.1 13.7 3.2 10.1 3.5 3.1 7.1 4.6 12.8 3.3 2.2 8.6 3.5 13.3 5.4 2.5 2.4 5.7 3.5 3.9 4.3 10.4 2.2 9.5 1.9 1.5 4.1 2.8 7.9 6.3 9.6 6.1 2.7 10.5 8.6 3.7 2.4 16.7 8.2 3.9 4.8 11.8 5.4 2.1 30.5 8.0 4.0 18.9 13.0 9.4 20.8 48.8 21.4 15.8 7.7 0.5 1.1 0.0 1.2 95.5 7.0 3.0 11.2 1.1 14.5 0.2 6.5 1.3 1.5 2.2 19.0 11.4 222.1 5.2 0.3 5.0 1.9 6.1 16.0 4.8 4.7 0.3 18.1 0.4 0.6 74.8 8.6 0.8 0.3 3.2 8.6 0.0 2.9 0.1 0.3 43.6 19.8 0.0 17.6 14.9 0.4 34.7 3.2 12.4 11.0 7.5 0.1 7.1 7.7 0.0 0.2 64.1 19.5 201.5 6.9 80.7 6.1 5.4 6.2 0.1 6.1 5.2 2.1 0.1 9.7 8.7 35.5 2.2 7.3 9.1 4.3 3.8 2.4 2.5 2.3 2.8 3.3 2.2 2.5 2.4 2.2 2.7 2.4 2.1 101.3 0.0 4.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 3.1 7.4 0.0 0.0 1.8 1.8 0.0 0.8 16.5 0.0 0.0 1.1 0.0 2.3 1.9 51.1 0.0 0.0 0.0 0.9 1.2 9.2 0.0 6.0 1.3 12.5 0.0 0.0 38.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 5.7 0.0 0.0 0.0 0.0 1.9 0.0 0.0 5.9 0.0 0.0 0.5 1.5 0.0 0.0 0.0 16.2 0.0 0.0 0.0 0.0 0.5 10.7 4.2 0.0 0.0 RGS22 "CT145, DKFZP434I092, PRTD-NY2" ENSG00000132554 "Regulator of G protein signaling 22" Q8NE09 8 99960936-100131268 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 61.3" "Group enriched" "Detected in many" 8 "Early spermatids: 619.6;Late spermatids: 1623.3" "Cancer enhanced" "Detected in some" "breast cancer: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RPMI-8226: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA053026 Supported "Nucleoli fibrillar center,Actin filaments,Cytosol" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoli fibrillar center" "Actin filaments, Cytosol" "HPA053026: " "unprognostic (3.04e-2)" "unprognostic (2.62e-2)" "unprognostic (4.61e-2)" "unprognostic (3.97e-1)" "unprognostic (3.47e-5)" "unprognostic (1.61e-1)" "unprognostic (2.32e-1)" "unprognostic (3.19e-2)" "unprognostic (1.47e-1)" "unprognostic (1.14e-2)" "unprognostic (1.05e-2)" "unprognostic (7.96e-3)" "unprognostic (1.98e-5)" "unprognostic (3.71e-2)" "unprognostic (1.31e-2)" "unprognostic (3.25e-3)" "unprognostic (8.36e-4)" 2.7 0.9 1.7 0.0 2.4 0.0 0.6 1.0 1.5 1.4 10.4 0.3 0.0 2.9 1.1 0.3 10.6 1.2 0.3 1.1 3.9 0.2 0.1 1.7 0.3 5.9 7.4 7.3 0.5 0.0 1.1 0.5 3.7 1.3 0.1 1.0 0.1 2.3 0.1 0.6 0.1 1.5 3.7 0.0 0.1 61.3 5.3 0.1 0.3 0.1 0.3 0.4 0.5 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.9 0.6 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.0 0.1 0.0 0.3 1.3 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.4 1.0 1.5 1.1 3.9 5.9 7.4 3.7 3.7 5.3 2.9 0.1 0.0 0.0 14.4 0.0 2.2 0.0 1.6 0.6 1.2 1.2 0.8 0.8 0.0 12.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 619.6 58.1 14.2 0.7 0.0 0.0 2.3 0.0 0.2 8.6 0.5 0.8 0.0 1.3 0.0 0.0 0.2 0.0 1.6 0.0 4.1 0.0 2.9 1623.3 131.4 0.4 0.0 6.5 0.0 10.9 0.0 20.1 2.5 0.0 0.0 62.8 0.0 0.0 0.0 0.0 77.2 0.2 0.0 0.4 1.6 70.9 11.1 0.1 2.0 0.8 0.4 8.3 0.0 0.1 RGS7BP R7BP ENSG00000186479 "Regulator of G protein signaling 7 binding protein" Q6MZT1 5 64506015-64612319 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.0" "Group enriched" "Detected in some" 5 "Excitatory neurons: 122.5;Inhibitory neurons: 170.6;Oligodendrocyte precursor cells: 67.8" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "cerebral cortex: 26.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "HUVEC TERT2: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039600 Approved Uncertain "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Actin filaments" "HPA039600: AB_2676591" "unprognostic (2.93e-1)" "unprognostic (3.39e-1)" "unprognostic (7.35e-2)" "unprognostic (4.77e-2)" "unprognostic (7.57e-2)" "unprognostic (8.59e-2)" "unprognostic (5.22e-2)" "unprognostic (8.81e-3)" "unprognostic (1.86e-2)" "unprognostic (7.64e-2)" "unprognostic (5.49e-3)" "unprognostic (1.83e-1)" "unprognostic (1.65e-3)" "unprognostic (3.39e-3)" "unprognostic (2.06e-3)" "unprognostic (6.46e-2)" "unprognostic (8.50e-3)" 1.9 3.2 3.2 0.5 12.2 0.0 0.5 1.0 26.0 4.0 0.0 0.6 0.9 2.3 3.7 1.7 7.8 1.7 2.6 7.2 1.2 2.0 1.0 1.4 0.3 0.2 3.3 2.4 0.2 0.1 0.8 0.0 0.0 5.3 0.7 4.8 1.8 7.4 0.1 0.3 1.0 1.4 0.0 0.7 0.8 0.8 10.2 0.0 0.3 1.0 0.1 0.9 0.5 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 12.2 1.0 26.0 7.2 1.2 0.2 3.3 0.0 0.0 10.2 5.0 0.4 0.0 0.0 5.5 0.1 0.0 0.1 0.1 0.6 6.5 0.7 1.1 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 2.1 5.1 4.6 0.0 2.7 122.5 0.0 0.0 0.8 0.0 4.7 0.0 0.1 23.2 0.1 0.0 0.0 170.6 0.0 0.0 0.3 0.0 1.9 7.2 0.1 0.0 12.2 0.0 3.6 0.0 67.8 6.4 0.0 0.0 13.9 0.0 0.1 0.0 0.2 2.2 2.1 6.6 0.1 13.2 0.3 0.6 0.4 0.0 0.0 0.2 0.0 0.0 0.2 RMDN1 "CGI-90, FAM82B, FLJ20665, RMD1" ENSG00000176623 "Regulator of microtubule dynamics 1" Q96DB5 8 86468257-86514357 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026495 Approved Supported "Actin filaments,Centrosome" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Centrosome "Actin filaments" "HPA026495: AB_1848414" "unprognostic (1.68e-2)" "unprognostic (1.52e-1)" "unprognostic (1.46e-1)" "unprognostic (3.13e-3)" "unprognostic (1.76e-1)" "unprognostic (1.50e-1)" "unprognostic (1.32e-1)" "unprognostic (1.81e-2)" "unprognostic (1.68e-1)" "unprognostic (3.02e-1)" "unprognostic (2.09e-1)" "unprognostic (1.60e-1)" "prognostic favorable (8.51e-4)" "unprognostic (2.08e-1)" "unprognostic (7.15e-2)" "unprognostic (4.71e-3)" "unprognostic (3.47e-1)" 35.6 26.1 25.8 20.9 30.1 24.7 24.3 30.4 27.8 15.5 25.3 26.7 28.7 17.6 19.8 29.4 21.1 22.5 63.0 23.0 29.5 51.7 56.8 23.4 30.3 29.8 29.7 17.0 17.5 26.3 12.9 18.9 30.0 21.2 29.0 30.9 16.4 20.7 71.7 32.8 29.2 20.2 28.3 25.2 30.6 26.4 29.6 23.0 50.4 70.5 31.5 20.1 16.3 30.5 64.0 27.1 31.3 17.8 60.3 97.8 38.5 45.9 41.1 35.8 34.6 32.2 39.9 76.2 38.1 38.2 33.2 61.0 39.8 46.0 42.1 64.6 31.9 40.2 32.8 82.1 32.1 18.4 1.0 53.3 42.6 47.6 72.9 63.9 81.6 44.3 42.4 40.7 57.5 57.3 65.1 8.6 15.9 111.3 67.5 36.6 43.6 78.9 42.5 39.3 14.8 32.8 38.2 149.2 67.6 32.5 83.9 33.6 44.6 39.5 64.0 50.8 28.2 52.4 46.5 59.7 51.2 28.7 54.4 16.4 38.5 94.2 26.6 50.7 31.1 42.2 27.1 31.3 45.2 30.8 22.3 29.0 15.5 39.0 70.3 51.3 43.2 30.7 25.8 30.1 30.4 27.8 23.0 29.5 29.8 29.7 30.0 28.3 29.6 30.5 24.0 41.7 39.0 38.8 23.8 13.5 13.2 40.1 22.2 14.5 16.8 15.0 117.3 20.0 42.4 20.2 16.7 42.5 29.9 22.2 49.0 42.9 97.8 28.3 26.6 24.3 10.2 27.3 22.5 53.0 57.1 24.0 32.1 24.8 1.3 18.9 21.8 57.7 53.7 20.2 29.9 20.6 18.3 40.1 14.8 77.1 13.1 28.3 16.0 33.7 48.5 27.4 21.6 42.3 51.9 45.8 17.2 9.1 21.8 9.2 45.7 73.0 34.4 21.5 0.0 19.9 32.9 65.7 33.5 31.0 15.5 28.5 21.6 53.1 26.9 15.2 RND1 "ARHS, Rho6, RHOS" ENSG00000172602 "Rho family GTPase 1" Q92730 12 48857145-48865870 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 131.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 205.5;Ductal cells: 220.6;Exocrine glandular cells: 147.1;Pancreatic endocrine cells: 350.9" "Cancer enhanced" "Detected in many" "liver cancer: 16.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "SK-BR-3: 67.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077800 Supported "Vesicles,Plasma membrane,Actin filaments" NA NA "Cluster 30: Non-specific - Translation" "Cluster 15: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "Vesicles, Plasma membrane, Actin filaments" "HPA077800: AB_2686854" "unprognostic (5.60e-2)" "unprognostic (3.21e-2)" "unprognostic (2.23e-1)" "unprognostic (1.16e-1)" "unprognostic (6.90e-2)" "unprognostic (1.32e-3)" "unprognostic (3.59e-2)" "unprognostic (7.43e-2)" "unprognostic (2.21e-3)" "unprognostic (2.97e-1)" "unprognostic (1.93e-1)" "unprognostic (1.66e-1)" "unprognostic (3.89e-1)" "unprognostic (8.38e-3)" "unprognostic (6.18e-2)" "unprognostic (6.60e-2)" "unprognostic (3.35e-3)" 9.6 0.8 24.4 2.6 26.9 1.8 5.6 18.9 40.6 1.6 15.4 4.8 2.4 3.9 1.0 3.1 2.7 14.5 7.3 26.8 20.4 4.4 131.8 37.9 1.0 21.4 23.6 1.2 2.8 2.4 8.0 1.2 21.9 6.5 1.9 1.7 3.9 0.8 1.0 1.6 2.6 2.4 19.9 0.8 23.4 0.9 22.1 2.4 15.4 0.6 2.3 14.0 2.7 23.2 1.1 7.9 3.8 2.0 0.8 0.0 0.6 0.0 0.4 1.2 1.3 4.9 1.7 6.0 1.4 0.0 0.4 0.1 3.1 0.3 0.7 1.8 1.9 0.8 0.0 3.0 0.4 1.8 1.1 0.0 0.2 0.6 0.8 0.0 2.0 3.9 0.2 6.0 0.0 10.2 0.9 0.5 8.9 13.6 0.5 1.9 0.4 2.6 1.1 1.5 0.0 1.0 0.2 67.7 0.3 9.1 6.9 0.4 0.2 0.0 0.7 0.0 0.9 2.9 5.4 10.9 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 24.4 26.9 18.9 40.6 26.8 20.4 21.4 23.6 21.9 19.9 22.1 23.2 28.9 28.9 205.5 5.9 8.5 11.5 8.4 14.1 9.1 2.5 37.5 25.4 3.8 18.6 27.5 1.8 8.4 1.1 9.0 21.7 0.0 220.6 0.4 4.5 2.0 87.3 31.5 2.7 10.6 147.1 0.7 10.5 55.5 12.6 15.2 0.8 6.1 10.9 1.2 0.0 2.7 11.4 18.3 0.8 24.1 0.0 0.0 6.6 14.2 1.0 6.4 3.0 0.0 7.1 1.0 350.9 42.2 0.4 6.5 19.5 11.1 1.7 7.7 3.6 0.0 5.8 16.7 0.8 1.6 4.3 10.5 1.5 9.9 0.6 5.4 8.6 RNF25 "AO7, FLJ13906" ENSG00000163481 "Ring finger protein 25" Q96BH1 2 218663892-218672002 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036420, HPA036421" Uncertain Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "Nucleoplasm, Actin filaments" "HPA036420: AB_2675114, HPA036421: AB_10669604" "unprognostic (3.22e-2)" "unprognostic (7.85e-3)" "unprognostic (1.34e-2)" "unprognostic (2.29e-2)" "unprognostic (1.33e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (6.58e-4)" "unprognostic (3.58e-2)" "unprognostic (2.67e-2)" "unprognostic (3.46e-1)" "unprognostic (2.04e-3)" "unprognostic (8.82e-2)" "unprognostic (1.26e-3)" "unprognostic (2.50e-1)" "unprognostic (1.37e-1)" "unprognostic (2.44e-1)" "unprognostic (6.69e-2)" 10.9 11.4 18.5 8.9 18.6 7.3 10.9 18.3 21.0 12.2 17.1 12.0 6.2 12.7 15.8 11.7 12.4 10.8 13.9 18.6 19.7 10.4 11.1 10.4 14.5 18.4 18.4 14.5 11.5 15.1 11.4 11.4 19.0 11.8 8.2 7.0 11.0 13.9 15.0 14.5 7.9 13.6 18.5 10.3 9.4 14.3 19.2 15.1 14.1 17.1 11.9 14.0 9.7 19.0 18.8 20.4 22.1 24.6 27.6 17.5 20.4 27.3 43.5 58.0 53.6 32.4 13.2 11.6 17.6 42.3 35.2 19.5 22.1 33.9 31.0 16.4 27.3 22.7 21.3 34.6 33.6 19.3 20.6 33.9 30.9 55.5 44.7 21.4 31.0 40.9 27.4 24.3 41.1 45.3 20.6 20.4 32.9 16.2 23.4 23.2 15.5 15.9 36.3 21.8 19.5 23.8 18.1 17.2 28.4 21.9 20.6 25.6 26.6 40.2 20.5 19.2 31.1 23.7 13.7 23.5 33.4 19.1 25.7 58.6 21.5 32.6 26.0 21.3 24.8 25.7 25.7 27.2 17.1 30.4 29.0 23.2 17.1 30.5 25.2 15.0 25.9 24.8 18.5 18.6 18.3 21.0 18.6 19.7 18.4 18.4 19.0 18.5 19.2 19.0 4.2 0.0 0.5 5.2 7.8 6.2 4.8 16.3 6.8 7.7 3.4 3.7 4.0 10.0 8.9 1.8 8.4 12.3 4.5 7.4 15.6 12.3 16.8 6.3 8.1 7.6 1.2 2.1 6.2 12.9 9.7 7.5 9.7 4.8 7.0 5.9 8.9 7.1 13.2 5.0 5.8 5.5 8.2 5.0 4.0 5.3 7.2 5.5 8.8 2.8 8.9 7.9 9.2 3.5 4.9 12.7 9.6 12.8 8.5 3.8 7.2 14.8 8.2 5.0 26.3 5.6 9.2 19.3 12.8 5.9 6.8 10.0 8.0 8.5 6.1 3.6 RTN4R NOGOR ENSG00000040608 "Reticulon 4 receptor" Q9BZR6 22 20241415-20283246 "Disease related genes, Human disease related genes, Predicted membrane proteins" Receptor "Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.3;liver: 12.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 12.1;Excitatory neurons: 14.1;Muller glia cells: 11.3" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 10 "amygdala: 8.0;basal ganglia: 20.0;cerebellum: 20.9;cerebral cortex: 24.3;hippocampal formation: 12.7" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 10.8" "Lineage enriched" "Detected in many" 9 "T-cells: 10.8" "Cell line enhanced" "Detected in many" "NB-4: 38.2;REH: 53.9;SCLC-21H: 31.3;SK-MEL-30: 25.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB012443 Supported "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 1900000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane, Focal adhesion sites" "Actin filaments" "CAB012443: " "unprognostic (1.28e-1)" "unprognostic (1.28e-2)" "unprognostic (8.29e-2)" "unprognostic (6.58e-2)" "unprognostic (3.49e-1)" "prognostic unfavorable (7.73e-4)" "unprognostic (2.19e-1)" "unprognostic (1.56e-1)" "unprognostic (3.44e-1)" "unprognostic (8.90e-3)" "unprognostic (1.21e-2)" "unprognostic (9.89e-2)" "unprognostic (1.80e-2)" "unprognostic (1.34e-2)" "unprognostic (1.30e-1)" "unprognostic (5.02e-2)" "unprognostic (3.07e-1)" 1.6 2.6 8.0 0.5 20.0 0.6 1.0 20.9 24.3 3.6 0.0 1.6 2.2 5.1 0.0 3.5 1.9 0.1 2.7 12.7 0.0 2.1 12.8 2.2 0.4 0.5 0.0 2.4 3.7 0.4 4.9 0.4 0.3 1.5 0.1 0.6 2.0 0.4 0.6 7.9 2.1 0.2 0.0 8.5 1.8 1.9 0.4 0.8 3.5 0.2 0.2 0.5 2.8 1.8 7.9 3.8 2.3 5.5 0.0 0.0 1.2 0.8 0.0 0.6 0.3 6.0 2.2 0.4 2.5 0.1 3.7 12.8 1.4 3.2 0.0 0.2 13.4 0.1 3.2 0.9 1.3 0.3 0.4 0.0 4.1 0.0 0.3 0.0 0.0 3.7 0.4 0.3 0.0 11.0 4.1 38.2 8.7 2.3 6.7 53.9 0.0 0.4 0.5 3.3 31.3 5.0 3.7 2.7 25.9 0.5 3.1 1.1 0.0 0.5 14.2 0.1 0.2 0.1 1.0 0.9 0.4 7.8 0.1 0.0 0.0 0.0 4.6 0.0 10.8 0.0 4.0 4.6 0.2 0.1 2.4 5.1 0.0 0.8 0.0 1.2 3.0 1.7 8.0 20.0 20.9 24.3 12.7 0.0 0.5 0.0 0.3 0.0 0.4 1.8 1.4 3.2 0.0 7.5 0.2 5.1 4.0 1.6 1.8 12.1 2.9 2.4 2.2 0.0 0.6 0.0 4.2 0.2 1.9 3.0 0.0 2.9 2.0 1.2 4.8 2.0 0.0 0.4 14.1 4.3 7.6 1.6 0.0 1.6 0.0 0.4 1.1 3.0 1.3 6.7 2.6 2.6 0.0 0.0 0.7 0.5 0.3 1.7 1.8 2.8 0.7 11.3 2.1 2.5 2.4 3.4 0.4 0.0 0.1 3.9 0.6 0.0 0.0 4.9 0.0 0.2 1.0 0.1 1.2 2.0 5.5 0.0 2.5 0.1 2.1 3.5 RTN4RL1 "DKFZp547J144, NgR3, NGRH2" ENSG00000185924 "Reticulon 4 receptor like 1" Q86UN2 17 1934677-2025334 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 20.6;Cone photoreceptor cells: 37.5;Excitatory neurons: 43.5;Horizontal cells: 33.7;Inhibitory neurons: 18.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "hippocampal formation: 12.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 10.9;HaCaT: 10.8;hTCEpi: 10.1;T-47d: 13.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044428 Uncertain Approved "Nucleoplasm,Plasma membrane,Actin filaments,Midbody" "Intracellular and membrane" Yes NA 35000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Actin filaments" "Nucleoplasm, Plasma membrane, Midbody" "HPA044428: AB_10963229" "unprognostic (5.23e-1)" "unprognostic (3.52e-2)" "unprognostic (2.06e-1)" "unprognostic (2.12e-1)" "unprognostic (2.93e-2)" "unprognostic (7.25e-2)" "unprognostic (2.61e-3)" "unprognostic (1.17e-1)" "unprognostic (8.97e-3)" "unprognostic (6.21e-2)" "unprognostic (2.55e-3)" "unprognostic (6.32e-3)" "prognostic unfavorable (7.69e-4)" "unprognostic (3.86e-2)" "unprognostic (1.05e-1)" "unprognostic (7.01e-2)" "unprognostic (3.15e-2)" 4.0 3.1 4.6 0.3 4.0 0.0 6.4 0.0 9.2 2.1 0.0 0.4 0.1 0.8 0.2 1.3 1.5 0.6 2.3 12.3 0.3 1.6 2.6 1.6 0.1 0.0 0.5 0.9 1.8 1.3 5.9 0.3 0.0 3.4 0.1 8.5 4.4 2.0 1.8 9.6 0.5 0.3 0.0 1.1 0.7 0.8 1.9 0.2 1.4 0.4 0.1 1.5 2.2 0.0 1.4 1.6 1.8 2.5 2.0 0.3 0.0 0.1 1.1 0.3 0.0 0.0 0.0 0.0 0.1 10.9 0.2 10.8 4.6 0.1 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 10.1 0.0 3.6 0.0 0.0 2.5 0.1 0.0 0.1 0.5 0.0 0.0 0.3 0.0 0.3 0.8 0.3 1.2 0.0 0.0 2.2 0.0 0.3 0.8 1.7 0.2 13.3 0.1 0.0 0.0 0.2 0.5 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 4.0 0.0 9.2 12.3 0.3 0.0 0.5 0.0 0.0 1.9 0.0 1.0 0.0 2.2 1.6 0.1 2.7 0.2 0.0 1.8 20.6 5.4 4.3 3.0 1.5 1.3 3.7 37.5 0.0 0.1 0.0 0.0 0.6 0.3 0.0 0.0 0.7 0.0 0.0 43.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 6.1 3.3 1.8 33.7 18.6 0.0 0.0 0.3 0.4 1.1 0.0 0.1 3.6 7.5 0.0 1.8 0.0 8.5 1.7 0.1 0.0 0.0 0.1 0.9 0.0 0.1 1.5 10.0 0.0 0.0 0.6 0.0 0.2 0.5 2.8 0.0 0.2 0.0 0.0 0.3 SCN9A "ETHA, Nav1.7, NE-NA, NENA, PN1" ENSG00000169432 "Sodium voltage-gated channel alpha subunit 9" Q15858 2 166195185-166376001 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 21.9" "Cell type enhanced" "Detected in many" "dendritic cells: 43.2;Hofbauer cells: 67.5;Inhibitory neurons: 48.2;Langerhans cells: 42.8;Oligodendrocyte precursor cells: 133.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 23.6" "Lineage enriched" "Detected in single" 26 "dendritic cells: 23.6" "Cell line enhanced" "Detected in many" "BJ: 23.0;BJ hTERT+: 16.8;HHSteC: 19.0;hTERT-RPE1: 15.6" "Region enriched" "Detected in many" 5 "hypothalamus: 9.3" "Low region specificity" "Detected in many" "CAB013679, HPA061843" Uncertain Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Actin filaments, Focal adhesion sites" "CAB013679: , HPA061843: AB_2684625" "unprognostic (2.10e-1)" "unprognostic (2.83e-1)" "unprognostic (1.13e-1)" "unprognostic (8.98e-5)" "unprognostic (1.47e-3)" "unprognostic (9.43e-3)" "unprognostic (2.28e-2)" "unprognostic (2.24e-1)" "unprognostic (2.23e-1)" "unprognostic (3.64e-1)" "unprognostic (1.45e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.30e-5)" "unprognostic (1.69e-3)" "unprognostic (6.74e-2)" "unprognostic (2.46e-2)" "unprognostic (2.46e-1)" 1.7 1.7 5.3 0.9 4.2 2.0 0.6 0.1 3.4 0.6 0.0 3.2 0.5 0.2 0.1 0.5 0.4 1.2 0.4 2.9 21.9 1.7 3.9 2.0 0.6 8.2 19.4 0.3 2.0 0.1 1.5 4.3 12.0 0.3 3.1 0.7 0.4 0.4 0.2 0.7 1.8 2.4 2.2 3.1 0.4 5.1 18.2 1.6 0.3 0.6 0.4 0.5 0.5 1.7 0.0 2.5 0.1 0.0 9.6 7.9 0.0 23.0 16.8 5.2 1.7 0.5 0.1 0.0 0.0 2.8 0.2 0.1 6.5 0.6 8.6 0.0 2.1 1.7 1.8 1.9 19.0 0.1 0.0 0.6 0.2 9.1 1.7 15.6 1.1 1.2 6.1 6.6 0.8 0.0 3.6 0.0 1.9 0.1 0.6 0.8 3.3 9.0 2.4 9.5 1.0 9.5 0.0 0.1 0.3 4.8 0.3 0.0 0.1 0.0 1.5 0.1 0.4 0.1 0.1 0.0 3.2 0.0 2.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.9 0.5 0.1 23.6 0.0 0.1 5.3 4.2 0.1 3.4 2.9 21.9 8.2 19.4 12.0 2.2 18.2 1.7 0.9 12.8 23.8 0.7 1.3 1.0 0.4 0.5 0.6 0.6 0.8 0.9 2.5 8.6 4.4 5.5 0.0 0.3 43.2 9.0 3.9 23.4 2.5 0.1 0.1 5.7 33.0 4.2 15.8 31.5 0.3 2.0 0.0 0.1 3.8 18.1 13.6 9.5 67.5 0.0 48.2 19.3 10.2 1.9 42.8 3.2 1.2 11.3 3.6 2.8 1.0 2.3 0.0 133.7 0.4 12.7 7.8 0.0 1.2 0.3 14.7 11.5 2.2 0.2 0.0 7.8 1.6 1.3 0.4 0.5 0.4 1.1 0.9 4.4 12.9 0.2 SCNN1D "dNaCh, ENaCdelta" ENSG00000162572 "Sodium channel epithelial 1 subunit delta" P51172 1 1280436-1292029 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 35.5" "Cell type enhanced" "Detected in many" "Astrocytes: 10.7;Early spermatids: 10.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-266/70: 9.3" "Low region specificity" "Detected in all" HPA026884 Enhanced Supported "Plasma membrane,Actin filaments" NA NA "Cluster 43: Testis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Actin filaments" "HPA026884: AB_10601501" "unprognostic (2.08e-2)" "unprognostic (2.08e-1)" "unprognostic (7.39e-4)" "unprognostic (1.06e-2)" "unprognostic (2.74e-1)" "prognostic favorable (1.60e-4)" "unprognostic (1.44e-2)" "unprognostic (1.81e-1)" "unprognostic (2.08e-2)" "unprognostic (1.14e-1)" "prognostic favorable (1.32e-4)" "unprognostic (5.27e-2)" "prognostic unfavorable (6.67e-5)" "unprognostic (3.13e-1)" "unprognostic (4.18e-2)" "unprognostic (2.13e-1)" "unprognostic (7.06e-2)" 5.6 7.1 10.3 1.7 10.4 3.2 6.0 11.7 18.1 11.1 5.9 9.4 5.2 8.0 0.9 4.0 14.0 1.2 6.2 9.7 7.5 7.7 13.7 3.7 2.3 10.7 8.5 14.7 4.8 0.7 18.5 1.1 10.9 9.7 0.3 1.7 5.8 1.7 3.4 4.7 7.6 0.8 6.9 8.0 6.3 35.5 9.9 0.9 6.3 1.4 0.7 5.1 7.6 11.7 0.5 4.2 1.6 4.3 1.1 0.6 0.7 2.8 0.8 1.3 1.5 0.8 2.4 3.0 1.5 1.2 2.2 0.7 0.7 0.6 0.2 5.8 2.5 0.4 5.9 1.1 1.1 0.1 2.9 1.8 0.9 2.3 0.0 1.8 0.4 5.5 2.1 7.0 0.3 1.5 1.2 2.0 0.8 0.5 3.0 8.1 0.3 0.7 0.6 0.2 2.2 3.1 1.2 1.2 1.9 0.6 5.4 1.6 1.2 2.6 2.1 4.1 0.9 9.3 0.6 2.5 2.3 5.2 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 10.4 11.7 18.1 9.7 7.5 10.7 8.5 10.9 6.9 9.9 11.7 1.7 3.2 2.3 10.7 1.0 0.8 0.2 1.2 1.2 3.7 2.2 3.4 4.0 0.0 1.7 0.0 4.2 0.1 0.6 1.0 0.0 0.5 10.5 0.6 2.1 0.6 1.2 2.7 5.2 0.5 0.4 1.7 4.1 1.3 2.5 3.2 0.7 3.5 0.4 5.0 6.0 0.4 0.0 0.8 0.5 4.0 0.9 1.1 0.0 1.0 0.1 1.4 0.0 4.5 5.4 2.0 3.8 1.9 0.7 0.1 3.9 0.7 1.9 2.8 0.0 1.8 1.5 2.8 2.2 0.8 1.6 0.0 1.0 0.5 0.9 0.3 SEC16B "LZTR2, PGPR-p117, RGPR, Sec16S" ENSG00000120341 "SEC16 homolog B, endoplasmic reticulum export factor" Q96JE7 1 177923956-177984303 "Predicted intracellular proteins" "ER-Golgi transport, Peroxisome biogenesis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 28.4;liver: 36.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 66.3;Late spermatids: 50.4;Proximal enterocytes: 34.8" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebral cortex: 2.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 6.6;CAPAN-2: 7.2;EFO-21: 5.4;HDLM-2: 5.8;Karpas-707: 4.8;RPMI-8226: 6.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA054292, HPA072913" Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Actin filaments" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum, Plasma membrane" "Actin filaments" "HPA054292: AB_2682439, HPA072913: AB_2732213" "unprognostic (2.31e-1)" "unprognostic (1.90e-1)" "unprognostic (6.78e-3)" "unprognostic (6.07e-2)" "unprognostic (1.69e-1)" "unprognostic (1.33e-1)" "unprognostic (6.39e-3)" "unprognostic (1.22e-1)" "unprognostic (2.27e-2)" "unprognostic (1.50e-2)" "unprognostic (4.76e-3)" "unprognostic (2.43e-1)" "unprognostic (7.34e-4)" "unprognostic (6.67e-2)" "unprognostic (1.66e-1)" "unprognostic (1.37e-1)" "unprognostic (1.05e-1)" 4.0 2.5 0.5 1.1 1.1 0.3 3.2 0.0 2.9 3.0 0.0 3.6 28.0 3.5 2.0 2.0 3.5 4.3 2.6 0.8 0.1 3.4 36.4 2.4 1.1 0.0 0.3 4.2 9.0 0.5 1.4 0.8 0.1 1.6 4.0 5.7 3.6 2.1 9.3 2.7 28.4 2.7 0.0 5.8 8.7 1.4 0.3 0.4 2.1 3.1 0.9 1.4 1.1 1.2 1.9 1.5 0.1 1.5 1.9 6.6 0.0 1.5 0.5 0.1 0.7 1.0 7.2 0.6 5.4 1.2 0.1 0.0 0.4 0.2 0.0 5.8 0.1 0.0 0.0 3.4 0.1 0.1 0.0 3.8 0.5 0.2 0.0 0.2 2.2 0.0 0.0 4.8 3.9 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.6 6.5 0.1 0.1 0.6 1.2 0.1 0.2 0.8 0.0 0.1 1.3 0.7 1.0 0.2 0.6 0.0 1.5 0.7 0.1 2.6 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.1 0.0 2.9 0.8 0.1 0.0 0.3 0.1 0.0 0.3 1.2 7.7 0.0 2.0 2.9 0.7 0.3 0.3 0.4 1.8 1.3 6.3 1.8 0.5 7.2 1.9 1.8 2.1 0.5 0.0 0.9 0.0 0.6 10.1 2.3 1.6 3.9 3.6 0.0 15.8 1.1 0.0 1.9 9.2 2.7 1.3 1.9 3.6 66.3 0.6 11.8 4.8 4.6 0.0 3.2 0.4 50.4 2.5 0.7 1.8 3.7 0.6 1.4 0.0 1.0 1.3 1.1 5.2 1.2 2.9 0.1 34.8 3.1 3.3 4.7 0.0 2.7 1.0 0.3 0.8 0.6 1.0 0.0 0.3 0.1 5.4 0.2 SEPTIN1 "DIFF6, PNUTL3, SEPT1" ENSG00000180096 "Septin 1" Q8WYJ6 16 30378133-30395991 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 16.7;lymphoid tissue: 35.9" "Cell type enhanced" "Detected in some" "B-cells: 6.7;Cytotrophoblasts: 11.4;dendritic cells: 25.9;Fibroblasts: 4.9;Hofbauer cells: 9.2;Plasma cells: 10.2;Syncytiotrophoblasts: 4.9;T-cells: 6.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 38.2;JURKAT: 48.5;MOLT-4: 66.3;REH: 39.0;U-266/70: 21.6;U-266/84: 33.4;U-698: 23.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA041566, HPA060339, HPA073635" Enhanced Approved "Actin filaments" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Actin filaments" "HPA041566: AB_10794671, HPA060339: , HPA073635: " "unprognostic (3.65e-3)" "prognostic favorable (9.72e-5)" "unprognostic (5.06e-2)" "prognostic favorable (3.04e-5)" "unprognostic (3.32e-4)" "prognostic favorable (6.63e-4)" "unprognostic (2.08e-1)" "prognostic favorable (7.24e-5)" "unprognostic (1.24e-2)" "unprognostic (6.52e-3)" "prognostic favorable (2.22e-4)" "unprognostic (3.46e-2)" "prognostic unfavorable (2.40e-7)" "unprognostic (1.48e-1)" "unprognostic (1.41e-1)" "unprognostic (3.95e-1)" "unprognostic (1.72e-2)" 1.6 0.9 1.0 3.6 1.1 0.7 1.1 1.2 1.9 1.9 1.0 3.4 4.1 1.4 0.7 2.0 2.0 0.3 0.8 1.0 1.1 1.4 1.9 2.6 15.3 1.0 1.0 1.6 0.8 0.5 0.7 0.3 1.1 1.7 0.0 0.1 3.2 0.8 0.2 1.3 16.7 0.7 1.0 35.9 4.4 0.2 1.4 16.0 1.9 0.6 6.6 2.0 1.6 1.0 0.3 0.0 0.1 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 38.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 7.3 3.0 0.0 0.0 0.3 0.0 5.1 1.2 0.2 0.1 0.1 0.0 0.7 0.0 48.5 0.3 16.7 0.0 0.0 66.3 1.4 0.0 0.0 0.7 39.0 0.0 2.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 21.6 33.4 23.2 0.6 7.0 0.0 118.4 2.5 102.2 319.3 2.3 245.1 170.1 286.7 292.4 9.6 179.4 264.6 268.7 8.5 230.4 1.6 270.6 329.6 272.6 1.0 1.1 1.2 1.9 1.0 1.1 1.0 1.0 1.1 1.0 1.4 1.0 1.2 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 11.4 25.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.3 4.9 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 4.9 6.1 0.0 0.0 0.0 SEPTIN10 "FLJ11619, SEPT10" ENSG00000186522 "Septin 10" Q9P0V9 2 109542799-109614143 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 56.4;Cardiomyocytes: 21.8;Cytotrophoblasts: 15.1;Extravillous trophoblasts: 59.4;Fibroblasts: 15.5;Hofbauer cells: 19.6;Smooth muscle cells: 11.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 3.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047860, HPA056304, HPA060310" Enhanced Supported "Actin filaments" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Actin filaments" "HPA047860: AB_2680187, HPA056304: AB_2683094, HPA060310: AB_2684249" "unprognostic (1.84e-1)" "unprognostic (4.29e-3)" "unprognostic (1.94e-2)" "unprognostic (3.18e-2)" "unprognostic (6.34e-2)" "unprognostic (3.41e-2)" "unprognostic (2.02e-3)" "unprognostic (1.80e-2)" "unprognostic (9.67e-2)" "unprognostic (8.61e-2)" "unprognostic (1.78e-2)" "unprognostic (1.21e-1)" "unprognostic (1.58e-2)" "unprognostic (3.05e-3)" "unprognostic (2.72e-1)" "unprognostic (2.55e-1)" "unprognostic (9.12e-2)" 57.0 24.2 16.1 22.6 29.5 0.7 52.9 29.8 20.3 41.5 58.7 52.0 22.3 44.5 21.7 88.4 33.4 41.8 41.7 15.1 24.2 43.4 66.5 60.4 18.4 46.8 29.5 46.7 20.3 26.9 9.5 50.4 41.6 40.6 39.8 13.6 34.7 42.2 28.5 73.4 24.3 58.0 31.9 36.3 30.5 76.9 26.1 19.9 43.3 39.0 22.8 55.1 43.2 44.5 104.7 27.7 99.6 64.1 78.1 145.8 61.1 166.5 290.6 114.8 133.3 52.2 59.0 0.0 82.2 130.4 72.2 47.7 42.8 105.2 151.6 199.4 31.2 0.2 38.5 75.3 58.7 0.2 13.4 91.5 46.9 103.5 135.1 123.9 154.3 0.0 2.7 0.4 141.5 9.9 0.1 10.3 74.4 61.3 53.7 0.1 80.9 17.4 95.7 136.8 29.6 61.8 97.8 2.1 77.0 115.2 26.5 1.2 158.5 120.1 85.1 46.9 69.6 61.4 36.0 0.9 106.7 2.3 148.1 0.0 2.4 0.0 0.1 1.6 0.1 0.8 1.5 0.4 0.6 0.3 0.7 0.2 0.1 0.0 1.0 0.0 3.5 0.8 16.1 29.5 29.8 20.3 15.1 24.2 46.8 29.5 41.6 31.9 26.1 44.5 56.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.8 0.0 0.0 0.0 0.0 15.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 59.4 15.5 0.0 0.0 0.0 0.0 0.0 0.0 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 7.5 0.1 0.0 0.0 0.0 SEPTIN2 "DIFF6, hNedd5, KIAA0158, NEDD5, Pnutl3, SEPT2" ENSG00000168385 "Septin 2" Q15019 2 241315100-241354027 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Spermatogenesis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 89.9;Cardiomyocytes: 133.5;Cytotrophoblasts: 135.9;Extravillous trophoblasts: 190.1;Hofbauer cells: 136.8;Syncytiotrophoblasts: 139.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017190, HPA018481" Supported Enhanced "Nucleoplasm,Plasma membrane,Actin filaments,Cytokinetic bridge" Yes No 3300000 "Cluster 27: Non-specific - Gene expression" "Cluster 57: Non-specific - Angiogenesis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 24: Non-specific - Transcription regulation" "Actin filaments" "Nucleoplasm, Plasma membrane, Cytokinetic bridge" "CAB017190: , HPA018481: AB_1856684" "unprognostic (6.31e-2)" "unprognostic (5.27e-2)" "unprognostic (2.95e-2)" "unprognostic (4.03e-2)" "prognostic favorable (8.21e-4)" "unprognostic (3.32e-1)" "prognostic unfavorable (3.66e-4)" "unprognostic (1.96e-3)" "unprognostic (1.83e-2)" "unprognostic (5.69e-2)" "unprognostic (1.11e-3)" "unprognostic (3.16e-1)" "unprognostic (9.58e-3)" "unprognostic (8.11e-2)" "unprognostic (9.53e-2)" "unprognostic (1.40e-1)" "unprognostic (2.17e-2)" 246.0 155.0 192.8 159.7 216.1 125.3 177.2 208.8 220.6 233.8 183.2 179.7 140.8 209.0 176.7 161.1 168.7 193.8 211.8 180.5 209.6 212.6 117.1 184.5 157.2 227.2 203.3 221.7 214.2 220.1 112.7 217.3 232.2 186.1 188.6 114.0 163.3 218.2 160.6 119.0 154.8 253.1 224.1 164.9 152.6 145.0 198.3 141.8 224.6 163.5 180.5 221.0 116.7 245.3 245.1 207.7 561.7 370.8 511.5 555.0 289.1 517.3 508.9 329.1 417.2 118.7 258.4 96.1 119.4 599.0 176.7 209.6 377.7 347.9 535.5 241.9 262.2 388.9 200.5 444.5 311.6 374.4 228.0 495.1 224.8 275.0 259.1 369.8 576.2 240.9 357.4 138.0 491.9 171.5 226.7 227.3 412.5 215.2 152.8 216.2 707.4 204.7 483.5 359.9 401.4 270.0 363.0 245.7 353.0 397.9 146.9 333.4 555.5 399.2 166.2 392.9 320.6 267.7 251.9 340.9 344.7 225.1 571.6 172.0 165.0 98.3 101.0 184.1 125.1 87.4 97.9 104.2 183.8 77.2 84.4 89.6 58.9 191.4 144.8 138.7 108.0 241.2 192.8 216.1 208.8 220.6 180.5 209.6 227.2 203.3 232.2 224.1 198.3 245.3 89.9 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 133.5 0.0 0.0 0.0 0.0 135.9 39.9 0.0 0.0 0.0 0.0 0.0 0.0 25.3 0.0 0.0 0.0 0.0 190.1 50.4 0.0 0.0 0.0 0.0 0.0 0.0 136.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.7 0.0 0.0 0.0 0.0 139.0 6.5 0.0 0.0 0.0 SEPTIN3 "SEP3, SEPT3" ENSG00000100167 "Septin 3" Q9UH03 22 41969475-41998221 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 233.7" "Cell type enriched" "Detected in some" 5 "Extravillous trophoblasts: 27.9" "Group enriched" "Detected in many" 5 "glioma: 24.6;melanoma: 11.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 26.6;Daudi: 22.3;SCLC-21H: 71.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003548, CAB017633" Supported Supported Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Plasma membrane" "Actin filaments" "CAB017633: AB_2301476, HPA003548: AB_1079908" "unprognostic (2.10e-1)" "unprognostic (4.67e-2)" "unprognostic (1.16e-2)" "prognostic unfavorable (1.78e-4)" "unprognostic (4.56e-2)" "unprognostic (1.13e-1)" "unprognostic (7.07e-3)" "unprognostic (2.37e-1)" "unprognostic (2.67e-3)" "unprognostic (3.09e-2)" "unprognostic (1.30e-2)" "unprognostic (6.30e-2)" "unprognostic (2.51e-2)" "unprognostic (9.15e-2)" "unprognostic (6.68e-2)" "unprognostic (5.50e-2)" "unprognostic (1.04e-1)" 0.2 4.6 134.7 0.4 160.5 0.1 1.3 82.4 233.7 0.2 30.5 0.8 0.3 0.2 1.4 0.2 0.1 0.4 0.2 167.0 89.5 0.3 0.1 0.7 0.5 86.2 73.4 0.2 1.2 18.6 7.8 5.7 83.8 1.3 0.5 28.4 0.4 0.0 0.1 1.6 0.4 0.3 56.9 0.2 0.7 2.1 91.4 0.9 0.8 0.2 0.5 0.3 0.4 150.7 1.5 1.7 26.6 20.1 0.3 0.0 13.3 0.3 0.3 1.8 0.8 0.4 3.1 22.3 0.7 0.2 11.4 0.1 14.0 0.1 0.7 9.2 4.6 0.1 0.5 0.0 0.2 0.0 0.9 0.2 1.0 0.1 0.0 0.0 0.0 12.1 0.0 3.4 0.0 2.4 3.7 0.2 18.2 0.2 0.7 17.9 0.0 1.3 0.0 2.7 71.4 14.8 10.9 0.1 18.2 2.5 2.6 6.7 0.0 0.0 9.2 0.9 1.0 14.1 13.1 0.2 0.3 9.0 2.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 134.7 160.5 82.4 233.7 167.0 89.5 86.2 73.4 83.8 56.9 91.4 150.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 SEPTIN5 "H5, HCDCREL-1, PNUTL1, SEPT5" ENSG00000184702 "Septin 5" Q99719 22 19714503-19724224 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 321.9" "Group enriched" "Detected in some" 9 "Cardiomyocytes: 3.4;Smooth muscle cells: 2.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 32 "eosinophil: 15.4;neutrophil: 5.8" "Lineage enriched" "Detected in single" 47 "granulocytes: 15.4" "Cell line enhanced" "Detected in many" "K-562: 281.6;THP-1: 75.9" "CAB016120, HPA029095, HPA063885" Enhanced Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA 860000 "Cluster 49: Eosinophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nucleoplasm, Actin filaments, Cytosol" "CAB016120: AB_628240, HPA029095: AB_2672904, HPA063885: AB_2685141" "unprognostic (4.07e-2)" "unprognostic (1.47e-1)" "unprognostic (6.78e-3)" "unprognostic (1.39e-2)" "unprognostic (3.92e-1)" "unprognostic (1.86e-1)" "unprognostic (2.50e-2)" "unprognostic (3.77e-1)" "unprognostic (5.66e-2)" "unprognostic (6.19e-2)" "unprognostic (1.88e-3)" "unprognostic (4.34e-1)" "prognostic unfavorable (6.87e-6)" "unprognostic (3.39e-2)" "unprognostic (2.93e-1)" "unprognostic (1.53e-2)" "unprognostic (3.30e-2)" 17.7 17.7 152.8 5.7 215.6 41.0 16.4 49.2 321.9 54.1 61.9 19.8 5.2 28.1 46.2 62.1 38.8 14.7 165.4 233.6 49.3 12.7 5.2 17.4 8.4 40.9 45.2 29.3 17.0 127.3 82.7 12.0 39.4 20.1 6.3 30.3 15.9 9.9 10.8 126.5 8.8 17.3 24.7 14.3 16.3 29.1 73.1 15.9 33.4 16.2 8.1 13.5 42.8 168.6 0.4 10.6 42.0 64.0 3.9 13.1 0.3 15.8 20.1 17.9 10.5 0.7 5.6 1.5 6.1 35.8 26.0 6.0 30.2 6.0 8.8 9.6 3.4 0.7 2.4 0.2 16.2 0.8 47.2 17.4 7.4 6.0 2.5 5.1 7.5 23.1 281.6 0.6 28.2 4.2 4.6 31.2 5.4 1.0 10.4 41.4 1.3 7.2 1.3 1.4 62.3 49.2 2.4 3.5 2.8 10.2 17.3 75.9 3.0 46.4 55.6 2.0 3.2 4.5 0.0 0.4 5.8 2.2 15.2 0.0 0.1 15.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 5.8 0.0 0.0 0.3 0.0 6.0 152.8 215.6 49.2 321.9 233.6 49.3 40.9 45.2 39.4 24.7 73.1 168.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SEPTIN7 "CDC10, CDC3, SEPT7, SEPT7A" ENSG00000122545 "Septin 7" Q16181 7 35800932-35907105 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 570.9" "Group enriched" "Detected in some" 4 "Adipocytes: 192.1;Cardiomyocytes: 227.0;Cytotrophoblasts: 171.4;dendritic cells: 196.6;Extravillous trophoblasts: 198.2;Fibroblasts: 153.5;Hofbauer cells: 191.0;Smooth muscle cells: 190.0;Syncytiotrophoblasts: 124.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023309, HPA029524" Enhanced Approved "Nucleoli,Plasma membrane,Actin filaments,Midbody,Cytosol" Yes No 4300000 "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" "Actin filaments" "Nucleoli, Plasma membrane, Midbody, Cytosol" "HPA023309: AB_10600093, HPA029524: AB_10601573" "unprognostic (7.91e-3)" "unprognostic (6.89e-3)" "unprognostic (9.49e-2)" "unprognostic (1.27e-1)" "unprognostic (1.04e-1)" "unprognostic (2.22e-2)" "prognostic unfavorable (2.37e-4)" "unprognostic (2.00e-2)" "unprognostic (4.43e-2)" "unprognostic (7.13e-2)" "unprognostic (3.56e-2)" "unprognostic (7.66e-2)" "prognostic unfavorable (2.78e-4)" "unprognostic (2.86e-2)" "unprognostic (1.74e-1)" "unprognostic (1.71e-1)" "unprognostic (2.43e-3)" 127.1 95.1 352.6 98.8 386.1 131.0 99.5 334.3 570.9 111.5 289.5 116.4 55.7 126.5 121.5 106.6 84.1 117.5 172.1 344.1 341.6 82.9 76.9 98.6 150.9 337.4 355.9 138.2 37.0 81.1 62.6 143.5 339.1 93.9 94.8 119.5 50.3 95.5 82.9 105.0 74.9 145.2 345.1 108.3 59.4 70.3 367.7 159.0 78.2 104.3 149.7 125.0 86.9 411.9 198.1 94.3 232.0 153.2 256.7 263.1 119.3 248.6 228.6 206.7 177.0 147.7 148.9 186.2 164.2 254.9 274.9 146.3 166.3 166.4 294.0 127.8 88.4 149.8 123.4 80.8 149.4 182.7 157.7 171.7 127.1 163.8 159.4 215.6 221.0 143.3 120.1 141.9 341.6 92.8 185.6 304.3 249.7 183.1 132.6 188.3 220.9 107.6 202.6 146.1 124.3 217.4 173.5 220.1 151.8 377.1 163.1 198.7 187.3 207.2 246.7 129.9 278.5 165.9 163.4 470.2 132.4 301.2 449.3 266.8 86.0 150.1 214.8 100.1 220.7 165.6 151.5 199.6 100.8 155.5 134.4 171.2 160.9 298.7 110.5 71.0 147.4 241.7 352.6 386.1 334.3 570.9 344.1 341.6 337.4 355.9 339.1 345.1 367.7 411.9 192.1 0.0 0.0 0.0 41.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 227.0 0.0 0.0 0.0 0.0 171.4 196.6 0.0 0.0 0.0 0.0 0.0 0.0 40.1 0.0 0.0 0.0 0.0 198.2 153.5 0.0 0.0 0.0 0.0 0.0 0.0 191.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 190.0 0.0 0.0 0.0 0.0 124.2 30.4 0.0 0.0 0.0 SEPTIN8 "KIAA0202, SEP2, SEPT8" ENSG00000164402 "Septin 8" Q92599 5 132750819-132807241 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 393.6" "Cell type enhanced" "Detected in some" "Adipocytes: 7.0;Cardiomyocytes: 14.1;Cytotrophoblasts: 31.0;Extravillous trophoblasts: 12.1;Fibroblasts: 9.5;Hofbauer cells: 12.1;Smooth muscle cells: 8.8;Syncytiotrophoblasts: 10.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005665, HPA036534" Enhanced Approved "Actin filaments,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 15: RT4 - Unknown function" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Actin filaments" "HPA005665: AB_1079910, HPA036534: AB_2797226" "unprognostic (2.06e-2)" "unprognostic (1.13e-1)" "unprognostic (9.24e-2)" "unprognostic (7.10e-3)" "unprognostic (2.70e-1)" "unprognostic (2.15e-2)" "unprognostic (2.86e-2)" "unprognostic (1.41e-2)" "unprognostic (1.58e-2)" "unprognostic (2.97e-2)" "unprognostic (2.38e-2)" "unprognostic (3.12e-1)" "prognostic unfavorable (6.98e-5)" "unprognostic (2.86e-2)" "unprognostic (4.30e-1)" "unprognostic (8.04e-3)" "unprognostic (2.70e-1)" 26.9 19.5 192.8 18.0 273.3 8.3 22.2 279.1 238.2 28.2 111.6 26.3 26.2 18.8 18.5 34.0 21.4 25.2 33.0 188.3 218.5 34.8 13.0 26.2 14.9 319.9 262.0 25.2 23.3 23.9 22.3 44.3 304.7 20.5 26.9 74.6 33.4 20.6 10.9 49.7 25.8 21.3 238.1 14.8 26.8 6.9 250.4 18.0 32.3 12.4 18.6 36.1 31.1 393.6 55.8 26.4 37.3 76.7 50.8 49.5 122.0 58.9 56.2 54.7 66.5 46.6 39.2 0.3 51.1 57.3 32.4 42.3 70.5 96.4 59.9 71.3 50.8 54.4 35.5 40.5 37.2 19.4 76.0 35.9 30.6 25.3 35.8 53.5 77.4 47.7 84.6 10.6 29.7 53.0 63.3 18.2 19.8 33.7 17.0 57.4 43.5 4.7 32.0 141.1 50.0 31.0 50.0 11.5 32.9 107.4 100.6 25.4 80.9 60.6 39.2 15.1 42.5 14.3 14.3 2.0 38.7 28.6 46.5 0.5 1.0 0.0 2.0 0.6 2.0 0.4 1.6 2.5 1.2 0.1 0.4 1.0 0.0 0.2 0.3 0.0 1.9 1.0 192.8 273.3 279.1 238.2 188.3 218.5 319.9 262.0 304.7 238.1 250.4 393.6 7.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.0 0.0 0.0 0.0 31.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 12.1 9.5 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 10.1 0.6 0.0 0.0 0.0 SEPTIN9 "AF17q25, KIAA0991, MSF, MSF1, PNUTL4, SEPT9, SeptD1" ENSG00000184640 "Septin 9" Q9UHD8 17 77280569-77500596 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 29.9;Cytotrophoblasts: 78.2;dendritic cells: 34.8;Extravillous trophoblasts: 152.8;Hofbauer cells: 67.5;Syncytiotrophoblasts: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042564, HPA050627" Approved Enhanced "Actin filaments" No No 770000 "Cluster 39: Non-specific - mRNA processing" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Actin filaments" "HPA042564: AB_2678054, HPA050627: AB_2681193" "unprognostic (7.65e-2)" "unprognostic (5.44e-2)" "unprognostic (5.46e-3)" "unprognostic (2.34e-1)" "unprognostic (2.65e-2)" "unprognostic (2.71e-1)" "prognostic unfavorable (1.61e-5)" "unprognostic (4.23e-3)" "unprognostic (1.56e-1)" "unprognostic (8.48e-2)" "unprognostic (1.99e-1)" "unprognostic (2.45e-1)" "unprognostic (1.49e-2)" "unprognostic (1.25e-1)" "unprognostic (1.35e-1)" "unprognostic (1.33e-1)" "unprognostic (2.80e-1)" 68.7 87.9 58.8 148.8 61.7 89.2 72.8 81.6 85.3 99.3 59.9 137.8 94.9 127.5 27.0 81.9 89.0 88.3 70.5 68.1 68.6 75.2 99.5 77.8 223.8 111.5 62.0 76.4 38.7 67.2 63.3 80.7 76.6 96.0 51.9 15.6 76.8 75.6 73.1 80.3 145.1 84.5 68.2 152.8 103.1 60.0 65.7 260.2 52.9 43.1 151.5 122.9 82.4 71.8 246.1 342.0 221.3 186.4 257.0 417.1 121.7 188.9 214.1 122.4 89.0 278.4 243.4 338.7 153.4 388.5 161.2 149.1 96.6 354.8 90.4 6.2 65.0 128.8 147.3 483.2 212.0 84.6 218.3 215.6 128.8 159.6 136.0 180.3 167.5 196.4 144.6 44.1 110.7 258.1 628.1 72.0 207.5 281.4 281.1 290.7 192.6 117.1 197.5 337.9 171.0 324.3 214.2 349.6 207.2 248.6 260.2 60.7 243.6 165.8 147.6 197.4 130.2 10.5 19.5 562.6 245.6 73.7 348.7 4.2 18.4 31.1 22.3 46.3 19.0 16.3 28.7 26.4 17.0 17.4 29.6 25.8 6.1 16.9 55.3 38.7 31.8 24.9 58.8 61.7 81.6 85.3 68.1 68.6 111.5 62.0 76.6 68.2 65.7 71.8 29.9 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 78.2 34.8 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 152.8 9.4 0.0 0.0 0.0 0.0 0.0 0.0 67.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 70.6 6.8 0.0 0.0 0.0 SHLD2 "bA163M19.1, FAM35A, FAM35A1, MGC5560, RINN2" ENSG00000122376 "Shieldin complex subunit 2" Q86V20 10 87094161-87191465 "Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 31.3;Endometrial stromal cells: 28.6;Glandular and luminal cells: 29.0;Proximal tubular cells: 48.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036582 Uncertain Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Actin filaments" "HPA036582: AB_10670233" "unprognostic (1.08e-1)" "unprognostic (2.72e-1)" "prognostic favorable (6.06e-4)" "unprognostic (1.77e-1)" "prognostic favorable (3.09e-4)" "unprognostic (5.34e-2)" "unprognostic (2.68e-1)" "unprognostic (2.19e-1)" "unprognostic (1.13e-1)" "unprognostic (8.20e-2)" "unprognostic (2.53e-1)" "unprognostic (9.18e-2)" "unprognostic (1.29e-3)" "unprognostic (1.12e-1)" "unprognostic (1.20e-1)" "unprognostic (6.44e-3)" "unprognostic (3.61e-2)" 15.6 20.1 10.8 12.6 8.4 9.6 17.3 7.3 10.0 11.9 10.2 15.7 22.3 11.4 7.0 12.8 11.2 10.7 10.3 8.6 10.5 32.1 37.2 11.6 13.1 27.5 10.9 12.7 12.4 6.1 10.9 9.7 8.8 14.9 16.5 15.6 14.3 9.5 10.6 12.0 24.8 12.2 9.3 11.9 12.0 8.0 10.1 10.4 23.3 11.7 14.4 13.3 11.2 8.7 33.6 26.7 14.9 34.4 16.4 15.8 21.7 22.1 31.0 29.0 31.8 30.8 25.2 24.4 12.1 30.2 17.0 21.9 37.2 16.9 29.8 35.1 24.6 33.9 24.3 29.1 25.4 53.4 28.5 14.5 30.4 26.6 45.4 25.6 19.6 26.3 43.7 42.7 27.2 19.2 43.7 37.8 17.2 24.2 18.4 26.8 29.6 27.0 26.6 27.7 7.4 30.6 17.1 19.9 29.8 13.7 44.0 29.6 19.4 16.5 15.0 24.8 44.7 23.9 55.8 58.5 27.8 65.4 9.1 7.1 7.3 2.8 6.7 11.8 13.7 9.2 10.0 10.0 11.3 8.8 10.0 10.1 0.1 12.5 9.5 3.9 10.4 8.7 10.8 8.4 7.3 10.0 8.6 10.5 27.5 10.9 8.8 9.3 10.1 8.7 21.2 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 20.9 13.2 0.0 0.0 0.0 5.5 0.0 7.2 17.4 0.0 31.3 12.6 0.0 16.7 28.6 4.2 0.0 0.0 0.0 13.7 15.1 7.9 0.0 29.0 0.0 20.2 0.0 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 8.8 0.0 0.0 0.0 0.0 14.7 0.0 0.0 7.6 0.0 0.0 48.2 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 2.2 7.8 19.1 0.0 0.0 SIGLEC10 "MGC126774, PRO940, SIGLEC-10, SLG2" ENSG00000142512 "Sialic acid binding Ig like lectin 10" Q96LC7 19 51410020-51417803 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 38.5" "Cell type enhanced" "Detected in some" "B-cells: 33.0;granulocytes: 39.3;Kupffer cells: 93.9;Macrophages: 51.5" "Cancer enhanced" "Detected in all" "glioma: 11.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 765.3;intermediate monocyte: 252.0;non-classical monocyte: 539.2" "Group enriched" "Detected in many" 16 "granulocytes: 765.3;monocytes: 539.2" "Cell line enhanced" "Detected in some" "Daudi: 28.8;HDLM-2: 9.0;HEL: 14.9;HMC-1: 10.7;NB-4: 10.4;U-698: 21.3;U-937: 12.0" "Not detected" "Not detected" "CAB025807, HPA027093" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Cytosol "Plasma membrane, Actin filaments" "CAB025807: , HPA027093: AB_1856858" "unprognostic (7.18e-2)" "unprognostic (3.90e-3)" "unprognostic (1.11e-2)" "unprognostic (3.67e-2)" "unprognostic (3.95e-2)" "unprognostic (9.41e-2)" "unprognostic (8.18e-2)" "unprognostic (2.11e-1)" "unprognostic (3.16e-2)" "unprognostic (1.83e-1)" "unprognostic (1.63e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.73e-1)" "unprognostic (1.69e-2)" "unprognostic (1.39e-1)" "unprognostic (9.05e-2)" 3.5 6.4 3.9 33.9 4.8 14.9 2.1 4.3 6.0 2.1 3.5 5.4 7.0 2.1 1.0 2.0 2.4 3.7 1.4 3.9 6.2 1.7 3.2 8.5 19.9 11.4 6.9 1.6 3.5 1.0 1.4 1.8 8.8 3.0 4.6 1.1 2.2 1.1 0.7 1.2 12.2 4.5 6.3 38.5 4.7 1.3 6.3 4.0 1.0 1.1 19.5 5.5 1.2 9.4 0.2 0.0 0.5 0.5 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.1 1.3 28.8 0.9 0.1 0.3 0.5 0.0 0.2 0.0 9.0 2.5 14.9 0.3 0.1 0.0 6.4 10.7 0.1 0.0 0.1 0.0 0.1 0.0 1.7 0.7 1.4 0.0 0.6 0.2 10.4 0.8 0.7 0.4 1.9 0.1 0.5 0.0 0.3 0.4 0.4 0.3 0.1 0.2 0.5 0.1 5.2 0.7 0.7 1.3 0.6 0.2 1.3 0.3 21.3 0.5 12.0 0.5 14.0 41.9 765.3 0.8 252.0 0.4 41.4 0.5 0.5 38.0 27.4 0.3 0.5 87.2 0.4 539.2 2.2 1.1 40.7 3.9 4.8 4.3 6.0 3.9 6.2 11.4 6.9 8.8 6.3 6.3 9.4 0.7 3.2 1.3 0.3 33.0 0.1 1.2 0.0 0.0 1.4 0.4 0.9 0.3 0.0 0.0 1.8 2.1 0.1 0.6 0.1 0.0 0.0 0.9 0.0 0.0 4.2 0.0 5.2 0.6 0.0 0.1 0.8 0.0 0.1 39.3 0.1 0.4 1.0 8.1 0.0 0.2 0.1 0.0 93.9 6.3 0.4 0.0 51.5 0.0 15.0 14.8 0.2 6.2 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.1 0.0 0.7 0.0 2.0 0.4 0.5 0.7 0.0 1.3 0.1 2.7 0.1 0.0 0.9 SIPA1L1 "E6TP1, KIAA0440, SPAR1" ENSG00000197555 "Signal induced proliferation associated 1 like 1" O43166 14 71320449-71741229 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 575.1;Inhibitory neurons: 447.6;Oligodendrocyte precursor cells: 221.2;Oligodendrocytes: 251.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 22.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-138 MG: 101.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002875, HPA077689" Approved Enhanced "Plasma membrane,Actin filaments" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 65: Brain - Ion transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Actin filaments" "HPA002875: AB_1079974, HPA077689: " "unprognostic (1.50e-3)" "unprognostic (2.99e-1)" "unprognostic (3.34e-2)" "unprognostic (5.64e-3)" "unprognostic (4.19e-2)" "unprognostic (4.14e-1)" "unprognostic (7.89e-2)" "unprognostic (4.86e-2)" "unprognostic (3.09e-1)" "unprognostic (8.62e-2)" "unprognostic (2.61e-1)" "unprognostic (5.27e-2)" "prognostic favorable (6.80e-8)" "unprognostic (1.02e-1)" "unprognostic (1.37e-1)" "unprognostic (1.42e-1)" "unprognostic (7.03e-2)" 6.2 14.5 29.7 11.6 33.4 11.7 9.0 6.1 27.8 9.4 31.3 12.1 10.3 7.1 11.0 14.4 13.8 15.5 3.3 30.9 4.5 14.9 12.3 11.5 11.0 2.7 0.5 4.7 12.7 19.2 16.0 5.1 1.4 7.9 11.7 13.3 10.7 8.5 3.0 8.7 11.1 10.5 0.6 25.3 18.1 19.8 10.1 12.5 14.3 2.8 15.8 12.7 6.1 11.3 27.0 8.3 18.9 14.2 5.6 16.0 34.2 35.9 42.4 14.3 18.1 48.1 14.8 12.6 9.1 59.1 12.9 26.1 13.9 32.3 27.1 11.4 6.5 26.5 55.3 11.3 46.3 3.2 9.8 11.7 26.7 22.1 52.0 16.3 15.5 17.5 11.8 30.7 19.8 40.5 10.8 3.0 10.8 24.6 22.4 15.7 20.4 13.4 10.2 41.1 23.2 61.9 36.8 28.6 2.6 12.1 17.0 1.4 43.3 101.4 37.2 11.6 20.8 25.0 30.3 18.3 17.3 8.6 34.6 6.9 5.2 1.1 1.7 5.8 3.8 3.2 1.5 2.4 1.3 7.4 1.0 1.1 22.9 2.2 7.1 0.4 1.6 2.3 29.7 33.4 6.1 27.8 30.9 4.5 2.7 0.5 1.4 0.6 10.1 11.3 14.4 67.3 30.5 163.9 53.8 11.9 15.2 20.2 30.7 19.6 13.0 21.2 5.3 21.5 23.6 14.7 18.8 7.8 23.9 19.3 13.7 24.6 74.4 28.8 18.8 12.9 32.4 1.3 575.1 19.9 8.5 11.3 46.9 35.3 13.9 26.4 5.0 17.5 5.1 58.9 447.6 16.8 10.2 21.4 67.2 31.2 7.8 49.2 5.4 120.9 34.6 58.2 9.2 221.2 251.3 23.0 15.5 35.3 24.9 16.2 18.3 28.4 34.4 15.9 0.0 5.4 18.2 22.4 36.8 17.3 8.4 9.4 24.3 102.0 22.5 27.2 SLC25A48 "FLJ44862, HDMCP" ENSG00000145832 "Solute carrier family 25 member 48" Q6ZT89 5 135579202-135889770 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 28.2;skeletal muscle: 8.8" "Cell type enhanced" "Detected in some" "Astrocytes: 31.0;Distal tubular cells: 9.8;Proximal enterocytes: 11.1;Proximal tubular cells: 45.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.7;HEK 293: 2.0;HEL: 1.7;RPMI-8226: 1.9;SCLC-21H: 1.9;U-2 OS: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA014674 Uncertain Approved "Intermediate filaments,Actin filaments" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Intermediate filaments" "Actin filaments" "HPA014674: AB_1859512" "unprognostic (2.09e-1)" "unprognostic (2.24e-1)" "unprognostic (6.34e-2)" "unprognostic (1.21e-1)" "unprognostic (1.37e-2)" "unprognostic (4.71e-2)" "unprognostic (1.96e-2)" "unprognostic (1.36e-1)" "unprognostic (4.62e-2)" "unprognostic (5.41e-2)" "unprognostic (3.57e-2)" "unprognostic (1.32e-1)" "unprognostic (8.02e-7)" "unprognostic (9.13e-2)" "unprognostic (1.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.20e-1)" 0.9 0.1 13.5 0.3 14.4 0.2 1.1 10.9 16.4 0.3 4.8 0.9 0.7 0.2 0.1 0.4 0.1 0.2 0.2 14.4 17.7 7.5 0.5 0.0 0.3 14.7 18.0 0.1 2.1 0.0 0.1 0.4 17.5 0.4 0.9 0.5 1.7 0.0 8.8 1.9 2.4 0.1 16.8 0.2 0.1 0.4 18.3 0.0 0.2 2.3 0.1 0.1 0.2 28.2 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.1 0.0 0.0 0.2 2.7 0.0 0.0 0.3 2.0 1.7 0.3 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 1.9 0.1 0.2 1.9 0.2 0.3 0.2 0.4 0.7 1.0 0.2 0.1 0.1 2.3 0.1 0.1 0.8 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 13.5 14.4 10.9 16.4 14.4 17.7 14.7 18.0 17.5 16.8 18.3 28.2 0.1 0.0 0.0 31.0 0.0 2.4 0.1 0.0 0.0 0.2 2.3 0.9 0.9 0.0 0.0 0.0 0.0 0.0 0.0 3.0 9.8 0.0 0.0 2.0 1.2 0.1 0.0 0.0 0.6 0.0 0.2 0.7 0.0 7.1 0.0 0.0 0.0 1.3 0.1 0.0 3.1 2.8 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.2 0.0 5.0 4.2 0.1 5.0 0.0 0.0 0.3 11.1 45.8 0.0 0.2 0.0 0.5 0.1 0.5 4.3 0.0 0.9 0.1 0.1 0.0 1.6 0.1 SLC46A3 "DKFZp686A1775, FLJ42613" ENSG00000139508 "Solute carrier family 46 member 3" Q7Z3Q1 13 28700064-28718970 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 76.0;liver: 96.0" "Cell type enhanced" "Detected in many" "Granulosa cells: 53.2;Hepatocytes: 51.3;Proximal enterocytes: 125.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 27.0;T-47d: 20.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039930 Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "Actin filaments" "HPA039930: AB_10673263" "unprognostic (5.16e-2)" "unprognostic (1.01e-1)" "unprognostic (1.15e-1)" "unprognostic (2.61e-1)" "unprognostic (3.88e-1)" "unprognostic (1.22e-1)" "unprognostic (4.53e-3)" "prognostic favorable (7.09e-4)" "unprognostic (3.13e-1)" "unprognostic (3.33e-1)" "unprognostic (1.26e-1)" "unprognostic (5.69e-2)" "unprognostic (7.35e-2)" "unprognostic (1.14e-1)" "unprognostic (5.60e-2)" "unprognostic (9.14e-3)" "unprognostic (6.47e-3)" 13.8 11.7 5.1 10.2 5.7 2.9 10.0 7.7 5.2 14.7 10.0 19.8 46.7 5.6 11.1 4.0 7.5 23.8 12.3 4.7 5.7 18.2 96.0 11.5 16.3 5.9 6.0 3.9 6.7 23.9 10.2 9.5 6.1 6.5 18.8 15.9 9.0 9.9 8.5 4.2 76.0 8.2 6.6 18.2 7.8 11.0 6.6 11.6 12.5 8.6 11.1 7.0 2.2 5.6 0.0 2.8 0.0 7.6 6.0 2.3 0.2 2.7 15.7 3.0 4.4 0.1 6.6 5.2 4.7 4.0 11.5 0.6 3.5 1.4 4.5 3.9 6.2 3.6 0.0 0.0 11.4 0.0 4.3 9.8 2.9 4.5 7.3 3.0 5.6 15.7 3.9 0.0 14.5 3.0 8.6 0.6 0.3 8.0 2.2 3.5 13.3 0.2 27.0 0.9 1.2 0.4 0.0 14.1 5.7 3.1 20.6 4.6 2.0 1.4 2.7 0.4 16.0 4.0 2.0 0.8 0.9 0.0 2.8 33.1 8.9 3.8 10.3 13.1 8.6 7.4 8.0 10.1 11.7 9.7 11.4 10.8 9.8 7.0 19.4 11.0 10.6 8.7 5.1 5.7 7.7 5.2 4.7 5.7 5.9 6.0 6.1 6.6 6.6 5.6 6.2 0.0 5.4 16.0 14.5 1.9 0.1 7.4 1.8 33.7 15.1 3.3 9.6 17.2 15.6 9.2 8.4 0.6 16.4 49.0 1.9 15.5 4.6 2.1 1.7 12.2 3.6 4.6 11.6 5.6 0.3 6.2 0.0 2.1 25.9 53.2 17.5 51.3 10.8 21.9 13.0 6.8 2.0 32.1 36.6 1.8 1.5 22.5 7.2 16.9 9.3 14.2 12.3 14.6 15.6 3.5 5.3 2.2 6.5 0.6 125.0 10.1 15.4 9.8 0.0 2.8 7.2 2.6 0.9 4.9 1.7 0.7 11.4 16.8 13.9 0.2 SLC5A9 SGLT4 ENSG00000117834 "Solute carrier family 5 member 9" Q2M3M2 1 48222685-48248644 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "intestine: 43.3" "Group enriched" "Detected in some" 4 "Alveolar cells type 1: 22.4;Proximal enterocytes: 84.0" "Cancer enhanced" "Detected in many" "liver cancer: 4.1;renal cancer: 3.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "Hep G2: 15.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA050263 Approved "Actin filaments,Cytosol" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Actin filaments" Cytosol "HPA050263: " "unprognostic (3.09e-3)" "unprognostic (1.89e-1)" "unprognostic (6.75e-2)" "unprognostic (5.66e-2)" "unprognostic (2.36e-1)" "unprognostic (1.35e-3)" "unprognostic (3.64e-2)" "unprognostic (4.59e-2)" "unprognostic (3.60e-2)" "unprognostic (1.59e-1)" "unprognostic (7.42e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.84e-5)" "unprognostic (4.56e-1)" "unprognostic (2.11e-1)" "unprognostic (4.30e-3)" "unprognostic (1.06e-2)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.2 0.8 43.3 0.1 1.2 0.2 0.1 2.5 0.0 0.0 0.0 3.8 7.8 3.0 0.0 0.2 0.2 0.0 3.9 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.8 0.1 1.1 42.0 0.0 0.0 0.0 0.5 0.5 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 15.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.2 0.3 0.2 22.4 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.5 2.8 0.0 0.0 0.0 0.0 0.0 3.1 1.9 0.5 6.3 0.5 0.1 0.1 0.0 0.0 0.3 0.2 0.0 0.3 0.0 0.5 4.5 0.0 0.7 4.4 0.1 0.0 0.2 2.9 0.0 1.3 0.0 11.0 0.3 0.3 0.0 1.9 0.1 0.0 0.0 7.5 2.9 0.1 1.7 0.4 0.0 0.0 84.0 4.1 0.0 0.0 0.0 0.2 0.1 0.6 0.3 0.0 0.0 0.0 0.1 0.0 3.0 0.0 SMTN ENSG00000183963 Smoothelin P53814 22 31064105-31104757 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 887.2;urinary bladder: 450.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 283.5;Hepatic stellate cells: 121.3;Sertoli cells: 184.1;Smooth muscle cells: 116.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "WM-115: 200.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001721, HPA051778, HPA058590" Enhanced Supported "Nucleoplasm,Actin filaments" No Yes 140000 "Cluster 30: Non-specific - Translation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "Actin filaments" "CAB001721: , HPA051778: AB_2681607, HPA058590: AB_2683765" "unprognostic (1.36e-2)" "unprognostic (4.84e-3)" "unprognostic (5.59e-2)" "unprognostic (1.96e-1)" "unprognostic (1.04e-1)" "unprognostic (1.41e-1)" "unprognostic (2.38e-3)" "unprognostic (1.08e-3)" "unprognostic (2.05e-2)" "unprognostic (4.56e-1)" "unprognostic (2.15e-1)" "unprognostic (7.22e-2)" "prognostic unfavorable (2.73e-5)" "unprognostic (2.75e-2)" "unprognostic (1.84e-1)" "unprognostic (8.41e-3)" "unprognostic (6.34e-2)" 54.7 19.2 10.8 25.3 12.5 4.7 42.2 10.3 13.1 100.2 7.6 887.2 30.0 251.0 7.0 65.1 132.4 20.8 152.0 9.0 9.3 35.6 15.3 38.2 5.6 11.7 12.5 34.0 25.2 3.3 9.8 17.4 11.0 150.9 29.2 15.2 16.3 177.9 95.7 38.7 151.5 127.2 10.5 54.5 231.2 12.5 12.4 2.9 26.4 26.2 2.5 450.6 91.5 10.0 73.0 21.2 7.2 27.0 11.0 17.2 58.0 106.8 49.1 85.7 58.4 29.9 22.4 32.1 9.3 59.3 17.3 10.6 7.2 62.8 40.4 10.6 58.2 33.9 18.3 36.1 9.7 51.5 57.4 14.2 5.8 114.0 18.7 29.2 74.7 12.3 37.3 25.9 59.6 64.5 5.9 11.4 8.2 36.1 90.0 20.3 20.5 34.6 34.5 23.2 11.5 12.7 33.4 15.9 15.7 7.4 18.8 8.2 118.7 62.1 58.4 59.4 79.8 24.6 32.5 18.8 91.0 19.7 200.5 0.0 1.0 0.0 0.1 0.2 0.0 1.3 0.1 0.3 0.4 0.0 1.0 0.5 0.1 0.1 0.2 0.2 0.0 0.6 10.8 12.5 10.3 13.1 9.0 9.3 11.7 12.5 11.0 10.5 12.4 10.0 94.5 6.4 3.3 23.8 2.0 65.1 33.5 16.1 19.4 46.6 18.6 26.7 39.5 5.7 6.1 9.2 283.5 13.4 2.7 12.8 9.8 14.8 1.2 4.0 52.1 62.8 29.2 0.0 0.2 20.1 68.8 35.9 18.3 7.3 0.0 11.0 121.3 2.6 6.0 5.0 1.9 29.9 14.2 6.8 14.6 1.9 22.4 4.7 14.2 7.5 1.0 31.2 1.0 4.5 2.0 73.2 11.4 48.5 2.1 21.7 5.6 18.4 2.2 54.0 184.1 18.4 116.4 5.7 7.9 9.7 69.3 21.9 3.7 16.3 27.0 14.9 SPECC1L "CYTSA, KIAA0376" ENSG00000100014 "Sperm antigen with calponin homology and coiled-coil domains 1 like" Q69YQ0 22 24270817-24417739 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA070614 Uncertain Supported "Actin filaments" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 21: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Actin filaments" "HPA070614: AB_2686287" "unprognostic (3.54e-1)" "unprognostic (4.93e-3)" "unprognostic (1.62e-1)" "unprognostic (5.88e-2)" "unprognostic (3.74e-2)" "unprognostic (1.28e-1)" "unprognostic (2.54e-1)" "unprognostic (7.82e-3)" "unprognostic (4.98e-2)" "unprognostic (1.72e-3)" "prognostic favorable (7.92e-4)" "unprognostic (3.15e-3)" "unprognostic (6.20e-3)" "unprognostic (1.40e-1)" "unprognostic (3.71e-1)" "unprognostic (5.79e-3)" "unprognostic (1.41e-1)" 13.0 13.1 12.3 12.4 12.8 13.3 13.8 34.0 13.5 16.6 17.7 15.8 7.8 15.9 9.7 17.5 15.5 12.5 18.6 10.8 15.7 14.6 14.4 17.2 12.5 18.1 16.2 22.0 13.3 17.3 14.6 10.1 18.9 20.1 16.9 10.7 16.2 15.1 12.7 9.2 11.6 19.0 15.8 11.1 11.5 31.9 16.6 14.5 24.0 13.1 13.8 14.9 13.0 13.7 31.1 22.8 42.9 23.7 40.1 39.2 14.5 43.1 34.1 36.8 36.4 25.5 8.4 44.9 10.3 39.5 29.0 27.0 39.2 24.2 43.4 26.1 21.1 28.5 12.9 23.4 26.7 51.2 27.0 33.1 19.2 32.8 34.2 28.8 44.0 18.9 24.5 19.0 39.3 17.3 26.6 18.5 20.7 22.5 17.1 24.0 43.3 16.1 18.4 23.3 37.2 38.3 36.5 27.5 23.8 37.1 18.3 14.4 46.3 77.2 43.7 19.3 29.3 22.7 23.4 20.0 22.6 19.0 29.2 3.9 2.4 4.8 3.3 3.5 2.5 2.8 2.2 1.6 2.3 3.1 2.7 2.9 3.2 1.3 1.6 3.7 1.6 1.9 12.3 12.8 34.0 13.5 10.8 15.7 18.1 16.2 18.9 15.8 16.6 13.7 11.6 16.0 21.3 0.0 10.4 3.6 2.7 5.0 10.2 8.4 13.8 9.4 13.7 14.3 9.1 12.9 10.4 7.3 7.9 32.8 1.9 6.7 26.9 8.3 14.9 12.0 14.4 7.6 0.0 7.4 3.2 11.4 8.2 9.8 16.5 13.4 15.7 11.4 7.3 10.1 0.0 12.2 14.2 7.3 2.2 93.7 16.1 6.9 14.2 0.0 14.8 6.4 9.2 0.0 0.0 9.0 15.0 13.5 10.7 5.7 8.9 6.1 11.9 8.5 13.1 11.3 12.5 24.1 28.5 9.8 3.1 5.9 9.3 7.6 8.0 3.8 SPON1 "f-spondin, KIAA0762" ENSG00000262655 "Spondin 1" Q9HCB6 11 13962723-14268133 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 101.4" "Cell type enhanced" "Detected in many" "Astrocytes: 399.9;Endometrial stromal cells: 78.9;Muller glia cells: 141.9" "Cancer enriched" "Detected in all" 5 "ovarian cancer: 199.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 3.3" "Lineage enriched" "Detected in single" 33 "T-cells: 3.3" "Group enriched" "Detected in some" 36 "EFO-21: 213.7;RPTEC TERT1: 604.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038584, HPA077546" Uncertain Approved "Nucleoplasm,Nucleoli,Actin filaments,Microtubule ends,Cytokinetic bridge" "Secreted to blood" Yes No 11500000 28000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoli, Microtubule ends" "Nucleoplasm, Actin filaments, Cytokinetic bridge" "HPA038584: AB_10697394, HPA077546: AB_2732351" "unprognostic (1.66e-1)" "unprognostic (1.03e-2)" "unprognostic (8.36e-2)" "unprognostic (8.72e-2)" "unprognostic (1.52e-1)" "unprognostic (3.76e-2)" "unprognostic (1.82e-1)" "unprognostic (8.20e-2)" "unprognostic (1.05e-1)" "unprognostic (5.93e-2)" "unprognostic (6.45e-2)" "unprognostic (1.07e-1)" "prognostic favorable (3.12e-4)" "unprognostic (7.22e-3)" "unprognostic (7.89e-2)" "unprognostic (4.65e-2)" "prognostic unfavorable (1.88e-4)" 54.2 16.9 25.8 18.6 33.7 0.1 19.5 26.3 22.3 43.8 7.8 31.8 31.6 36.5 15.2 17.3 63.1 101.4 30.6 28.2 28.3 12.2 2.0 49.2 1.6 25.6 33.6 23.9 4.6 0.8 10.0 41.3 26.4 16.9 46.6 63.8 7.0 8.8 0.8 8.8 28.4 46.9 14.9 8.3 28.8 2.5 34.0 1.7 5.2 1.6 1.2 51.5 12.5 21.8 0.1 0.1 0.4 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 9.8 0.2 0.2 213.7 0.0 0.2 0.4 0.0 0.0 0.0 0.3 1.9 0.0 0.1 0.1 0.0 0.0 0.1 11.4 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.1 2.7 0.0 0.1 1.7 0.0 0.1 604.1 0.1 0.1 0.2 0.0 0.0 0.0 4.1 0.0 0.1 2.6 0.2 0.7 0.5 0.3 0.3 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.3 0.0 0.6 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 25.8 33.7 26.3 22.3 28.2 28.3 25.6 33.6 26.4 14.9 34.0 21.8 0.2 0.0 2.3 399.9 13.5 0.0 17.3 0.0 1.2 13.5 2.0 5.5 1.9 5.7 0.0 0.0 2.1 3.4 4.8 38.9 3.9 4.3 1.5 36.1 78.9 2.5 16.7 0.0 17.0 2.0 4.2 41.2 0.5 61.5 2.5 1.8 2.5 0.2 1.9 1.7 16.8 24.0 0.0 0.3 0.0 1.3 4.4 1.0 0.0 11.2 0.5 141.9 20.6 62.4 1.6 6.8 20.6 30.1 0.9 9.0 18.4 2.1 0.7 26.8 6.6 5.8 7.0 0.4 0.8 0.6 0.0 4.9 7.8 1.1 40.9 9.4 SPRY2 hSPRY2 ENSG00000136158 "Sprouty RTK signaling antagonist 2" O43597 13 80335976-80341126 "Disease related genes, Plasma proteins, Predicted membrane proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 4.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 267.9;SK-MEL-30: 156.9;WM-115: 136.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037205, HPA042198" Approved Supported "Actin filaments,Microtubules" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Actin filaments, Microtubules" "CAB037205: AB_261923, HPA042198: AB_2677896" "unprognostic (9.37e-3)" "unprognostic (3.71e-2)" "unprognostic (1.10e-1)" "unprognostic (9.12e-3)" "unprognostic (3.80e-2)" "unprognostic (8.99e-2)" "unprognostic (3.95e-3)" "unprognostic (2.43e-2)" "unprognostic (3.43e-2)" "unprognostic (1.46e-1)" "unprognostic (1.53e-1)" "unprognostic (4.28e-2)" "unprognostic (1.56e-2)" "unprognostic (9.89e-2)" "unprognostic (3.22e-1)" "unprognostic (1.04e-1)" "unprognostic (1.86e-2)" 69.6 24.1 37.4 11.8 38.0 29.5 66.2 57.6 42.9 31.0 27.7 40.4 17.6 29.3 15.3 20.0 46.7 30.1 50.9 38.5 36.0 21.1 27.8 31.5 8.9 50.2 40.4 16.9 27.4 10.2 17.3 13.9 40.2 26.2 27.3 34.2 34.8 18.9 39.1 26.5 25.4 23.5 42.0 30.8 25.9 4.1 39.7 11.3 27.1 41.4 4.9 27.0 30.8 43.4 1.8 7.6 84.2 267.9 108.4 70.6 5.8 69.3 31.1 15.3 18.2 34.9 10.3 0.0 11.6 28.5 10.6 6.7 4.8 13.9 17.0 0.1 15.3 12.0 4.5 8.9 24.9 63.4 4.8 31.8 14.6 26.1 63.3 95.6 29.9 13.0 4.4 0.3 35.0 1.5 8.6 28.8 33.7 23.6 19.6 25.6 112.0 0.2 28.8 11.7 1.0 46.7 5.7 3.1 156.9 32.9 6.3 56.0 44.3 14.3 5.6 30.3 13.6 0.1 0.1 0.0 97.6 23.9 136.9 0.0 0.0 2.1 0.3 0.0 0.1 0.4 0.0 0.8 0.9 0.0 0.0 0.1 0.0 4.1 0.0 0.1 0.0 0.1 37.4 38.0 57.6 42.9 38.5 36.0 50.2 40.4 40.2 42.0 39.7 43.4 48.5 25.6 29.3 59.4 2.9 43.5 38.0 12.5 53.5 5.9 12.4 21.3 20.5 18.6 6.3 1.8 6.2 8.7 12.1 33.4 5.9 11.3 0.3 25.2 17.6 22.3 12.0 8.4 22.1 8.0 2.9 65.9 11.2 41.7 16.4 7.2 32.5 17.0 10.9 8.4 15.3 36.1 4.1 27.3 10.7 1.5 29.5 12.2 14.2 15.9 0.8 68.5 3.1 39.7 17.6 18.0 33.7 5.7 1.7 23.1 7.2 8.3 4.8 23.3 26.3 57.7 67.6 0.1 1.5 16.2 29.1 9.6 11.1 8.5 27.6 11.9 SPRYD3 FLJ14800 ENSG00000167778 "SPRY domain containing 3" Q8NCJ5 12 53064316-53079404 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039426, HPA039685" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "Vesicles, Plasma membrane, Actin filaments" "HPA039426: AB_10673358, HPA039685: AB_2676623" "unprognostic (7.73e-3)" "unprognostic (6.55e-2)" "unprognostic (1.37e-2)" "unprognostic (5.05e-3)" "unprognostic (1.52e-2)" "prognostic unfavorable (9.46e-4)" "unprognostic (1.27e-3)" "unprognostic (2.58e-1)" "unprognostic (1.83e-2)" "unprognostic (1.43e-2)" "unprognostic (2.64e-2)" "unprognostic (3.14e-2)" "prognostic favorable (1.78e-15)" "unprognostic (9.82e-2)" "unprognostic (5.27e-2)" "unprognostic (7.44e-3)" "unprognostic (1.41e-1)" 32.2 29.2 70.6 18.4 77.9 6.4 30.2 35.6 84.2 33.6 38.1 32.8 18.9 38.1 36.2 31.7 45.1 20.4 42.4 79.9 60.4 29.5 22.1 23.6 17.4 61.7 55.1 43.5 50.0 43.3 60.7 14.0 61.5 34.5 17.0 39.3 43.9 40.6 21.2 27.0 23.4 31.6 43.8 24.3 35.8 11.5 58.0 13.7 34.6 23.1 20.6 36.5 30.7 67.9 28.4 43.0 5.6 11.5 45.4 22.4 7.3 42.6 22.2 16.1 10.1 7.4 23.8 18.6 34.2 53.5 19.2 26.0 7.6 32.9 10.5 19.4 11.3 11.5 25.5 16.9 34.0 22.3 20.1 20.2 51.6 23.1 34.9 31.6 33.5 9.3 10.4 45.3 28.5 62.3 16.3 11.7 3.2 23.1 30.8 7.1 9.5 38.4 20.6 22.3 9.4 8.9 37.3 34.6 18.1 3.0 31.8 16.7 46.4 18.1 17.9 40.9 29.0 24.7 24.1 5.4 53.8 19.5 22.4 29.9 16.7 47.5 32.7 28.9 30.9 14.6 22.4 26.9 15.5 11.3 18.8 22.7 25.8 17.0 32.8 7.4 13.5 28.9 70.6 77.9 35.6 84.2 79.9 60.4 61.7 55.1 61.5 43.8 58.0 67.9 13.4 3.2 10.1 4.9 13.3 5.7 19.5 12.0 13.1 46.4 11.3 8.8 20.4 17.2 10.4 18.4 8.4 6.2 8.8 9.1 11.7 30.4 0.9 21.2 10.9 17.1 11.5 2.1 14.4 36.5 14.6 22.9 15.8 16.1 10.1 5.1 18.9 9.1 11.8 43.7 13.5 13.8 10.2 11.7 5.7 2.7 16.1 10.3 10.6 3.7 15.0 38.5 16.5 4.5 5.6 28.6 9.3 33.1 19.1 20.8 10.7 15.6 18.2 23.8 19.7 11.1 20.0 4.5 3.9 12.0 9.5 4.2 14.9 5.1 7.9 16.4 SRMS "C20orf148, dJ697K14.1, PTK70, SRM" ENSG00000125508 "Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites" Q9H3Y6 20 63540810-63547504 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "stomach 1: 1.6" "Cell type enriched" "Detected in single" 4 "Gastric mucus-secreting cells: 3.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.3;MCF7: 3.0;OE19: 4.4;RT4: 6.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB044668, CAB044669, HPA073987" Uncertain Approved "Intermediate filaments,Actin filaments,Cytosol" No NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 43: Cardiomyocytes - Nuclear processes" "Intermediate filaments" "Actin filaments, Cytosol" "CAB044668: AB_10609403, CAB044669: AB_10608235, HPA073987: AB_2686650" "unprognostic (2.26e-2)" "unprognostic (1.26e-2)" "unprognostic (2.52e-3)" "unprognostic (8.32e-2)" "unprognostic (2.62e-1)" "unprognostic (5.47e-3)" "unprognostic (1.65e-1)" "unprognostic (2.28e-1)" "unprognostic (9.63e-2)" "unprognostic (6.48e-3)" "unprognostic (7.28e-3)" "unprognostic (1.46e-1)" "unprognostic (1.73e-3)" "unprognostic (2.58e-3)" "unprognostic (4.75e-2)" "unprognostic (4.97e-2)" "unprognostic (2.54e-3)" 0.0 0.0 0.1 0.2 0.1 0.1 0.4 0.6 0.2 0.0 0.0 0.7 0.2 0.0 0.7 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.8 0.0 0.0 0.4 0.2 0.0 0.1 0.9 1.6 0.2 0.1 0.0 0.1 0.0 0.1 0.3 0.0 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.3 0.1 1.3 0.0 0.0 1.5 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.0 0.0 0.1 0.0 4.4 0.4 0.0 0.1 0.0 0.0 6.0 0.4 0.5 0.1 1.2 0.2 0.0 1.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SSH3 "FLJ10928, FLJ20515" ENSG00000172830 "Slingshot protein phosphatase 3" Q8TE77 11 67303478-67312607 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 11.6;eosinophil: 11.1" "Lineage enriched" "Detected in many" 5 "granulocytes: 11.6" "Cell line enhanced" "Detected in many" "HaCaT: 64.9;MCF7: 64.1;RT4: 111.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019949, HPA019957" Approved Approved "Nuclear speckles,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Nuclear speckles, Cytosol" "Plasma membrane, Actin filaments" "HPA019949: AB_1857498, HPA019957: AB_1857499" "unprognostic (4.38e-2)" "unprognostic (1.37e-1)" "unprognostic (3.50e-3)" "unprognostic (3.73e-2)" "unprognostic (2.61e-3)" "unprognostic (9.30e-2)" "unprognostic (2.99e-1)" "unprognostic (1.84e-1)" "unprognostic (1.63e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (2.89e-4)" "unprognostic (1.50e-1)" "unprognostic (2.06e-2)" "unprognostic (1.47e-1)" "unprognostic (3.20e-1)" "unprognostic (4.94e-3)" "unprognostic (6.78e-3)" 14.4 7.8 8.9 4.0 12.0 9.3 16.2 14.1 11.6 25.9 9.5 19.3 13.3 16.0 7.5 41.9 18.3 11.5 12.5 9.1 10.1 13.1 10.9 12.7 3.1 14.6 10.8 23.5 15.3 9.8 9.7 6.5 13.2 29.9 9.3 1.2 26.2 28.8 6.8 25.2 15.0 6.1 12.3 9.4 20.1 2.3 11.5 1.9 16.3 3.8 4.8 37.4 32.5 14.9 17.3 18.7 0.4 0.6 11.4 11.8 18.8 10.3 13.7 5.6 5.1 21.2 46.8 1.0 32.5 10.5 11.9 64.9 6.0 46.4 2.8 3.6 6.3 4.3 32.2 9.9 8.2 0.9 16.0 12.2 40.5 8.3 8.3 12.9 6.3 0.4 0.1 1.5 6.2 64.1 0.8 7.3 4.2 48.9 13.8 20.6 0.6 3.1 18.2 111.2 3.7 5.8 24.8 41.0 12.8 6.3 57.1 15.3 10.4 4.5 9.8 12.7 2.7 1.5 0.9 0.5 12.7 6.9 4.9 11.6 1.5 11.1 2.0 2.3 1.7 0.2 1.9 1.7 1.7 0.1 0.8 0.8 4.4 1.5 1.1 1.1 1.8 1.1 8.9 12.0 14.1 11.6 9.1 10.1 14.6 10.8 13.2 12.3 11.5 14.9 7.6 3.2 8.7 8.5 0.9 7.0 20.8 25.2 11.4 0.8 21.3 17.3 3.8 20.0 23.4 16.5 0.0 15.1 3.3 28.3 3.9 19.4 0.1 8.3 5.6 4.7 3.6 5.2 4.2 21.6 24.9 8.0 20.9 17.8 3.8 8.1 3.9 5.0 7.7 1.7 5.3 14.4 24.4 6.2 3.1 0.6 13.1 4.8 8.8 2.8 9.2 4.8 7.2 0.0 15.9 20.0 21.0 12.0 0.7 15.4 20.2 7.4 11.6 0.5 0.0 4.9 9.2 0.5 0.4 27.0 10.4 15.7 4.4 5.3 21.4 26.8 STMND1 FLJ23152 ENSG00000230873 "Stathmin domain containing 1" H3BQB6 6 17102050-17131378 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 17.8;gallbladder: 5.3;testis: 5.7" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 93.8;Respiratory ciliated cells: 72.8;Spermatocytes: 18.7;Spermatogonia: 23.8" "Group enriched" "Detected in some" 6 "breast cancer: 4.1;endometrial cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HEK 293: 2.4;SCLC-21H: 6.0;T-47d: 7.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA067970 Enhanced Approved "Actin filaments" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Actin filaments" "HPA067970: AB_2685934" "unprognostic (7.70e-2)" "unprognostic (1.03e-1)" "unprognostic (2.70e-2)" "unprognostic (2.09e-3)" "unprognostic (6.88e-2)" "unprognostic (6.64e-2)" "unprognostic (4.29e-2)" "unprognostic (4.22e-2)" "unprognostic (3.13e-2)" "unprognostic (1.22e-1)" "unprognostic (9.72e-2)" "unprognostic (5.29e-4)" "unprognostic (7.14e-2)" "unprognostic (1.10e-2)" "unprognostic (2.19e-2)" 0.0 0.0 0.2 0.1 0.2 0.0 3.0 0.3 0.4 0.8 2.2 0.9 0.1 0.5 0.3 0.0 17.8 5.3 0.0 0.3 0.2 0.0 0.1 2.4 0.0 0.5 0.5 0.0 3.5 0.0 0.5 0.1 0.3 0.0 0.8 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.5 0.0 0.0 5.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.2 0.5 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.0 0.0 0.0 0.0 0.0 0.5 7.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.1 0.2 0.0 0.0 0.2 0.2 0.3 0.4 0.3 0.2 0.5 0.5 0.3 0.5 0.2 0.6 0.0 0.0 1.3 0.0 0.0 0.0 1.7 2.9 0.0 0.1 5.0 1.4 0.7 2.8 8.3 0.0 0.0 0.0 0.0 1.2 0.0 0.6 1.3 93.8 0.9 0.5 1.8 0.0 0.5 0.2 0.0 0.4 0.0 2.3 0.0 0.7 0.0 0.3 0.0 0.0 0.2 0.7 2.0 0.0 0.4 2.8 0.0 0.3 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.6 0.3 0.4 0.0 0.7 0.0 0.0 72.8 0.0 6.6 1.3 2.7 18.7 23.8 0.0 0.9 0.0 0.3 0.0 1.8 0.6 STOX2 DKFZp762K222 ENSG00000173320 "Storkhead box 2" Q9P2F5 4 183797692-184023526 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 181.7;Inhibitory neurons: 192.3;Microglial cells: 72.1;Oligodendrocyte precursor cells: 91.0;Oligodendrocytes: 153.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 13.2;HeLa: 12.7;NTERA-2: 16.8;SH-SY5Y: 15.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049776, HPA065002" Uncertain Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "Actin filaments" "HPA049776: AB_2680875, HPA065002: " "unprognostic (9.79e-3)" "unprognostic (3.46e-1)" "unprognostic (2.10e-1)" "unprognostic (6.57e-3)" "unprognostic (3.33e-1)" "unprognostic (6.41e-2)" "unprognostic (4.57e-4)" "unprognostic (8.97e-3)" "unprognostic (1.25e-1)" "unprognostic (1.86e-1)" "unprognostic (3.75e-2)" "unprognostic (1.86e-1)" "unprognostic (7.06e-2)" "unprognostic (1.64e-1)" "unprognostic (1.71e-1)" "unprognostic (2.52e-3)" "unprognostic (2.49e-1)" 1.8 1.6 8.3 0.7 8.2 6.0 1.8 4.2 13.3 2.1 2.3 1.7 0.9 1.9 3.4 5.0 2.7 1.3 3.6 11.1 3.1 2.7 2.0 2.1 0.6 2.7 3.9 3.3 4.9 4.0 7.0 1.4 3.9 2.3 0.9 3.8 7.3 2.3 2.1 3.9 1.3 1.8 2.0 4.1 2.3 0.9 6.6 4.1 5.8 2.1 1.1 2.5 3.3 11.5 2.1 4.3 13.2 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.3 1.7 0.0 2.6 0.0 2.7 0.2 7.4 1.2 0.0 0.0 5.9 0.0 12.7 0.1 0.0 0.8 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.5 0.0 1.8 0.0 0.6 0.0 0.1 16.8 0.0 0.6 0.1 4.8 0.0 3.1 4.1 6.8 15.8 3.2 0.0 0.0 4.7 0.2 0.4 0.0 0.0 2.8 0.0 0.1 0.1 3.8 2.1 0.6 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 8.2 4.2 13.3 11.1 3.1 2.7 3.9 3.9 2.0 6.6 11.5 12.7 12.8 22.1 39.2 0.4 4.2 6.0 3.7 8.6 28.2 3.8 4.6 20.7 5.7 8.7 7.3 0.0 2.7 0.0 0.2 3.9 5.4 1.2 7.2 0.7 18.5 1.8 0.0 181.7 3.1 2.1 5.8 3.1 3.7 0.0 0.3 21.4 5.6 1.1 33.7 192.3 0.4 2.0 2.2 1.5 2.6 0.6 0.8 1.8 72.1 0.0 12.4 0.0 91.0 153.5 2.1 0.0 4.5 1.3 5.2 0.0 4.0 16.8 3.4 0.0 4.8 4.5 0.6 2.0 17.8 3.3 0.7 0.7 3.6 0.4 3.4 STRN3 "PPP2R6B, S/G2NA, SG2NA" ENSG00000196792 "Striatin 3" Q13033 14 30893799-31026401 "Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003392, HPA004636, CAB069925" Approved Supported "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "Nucleoplasm, Actin filaments" "CAB069925: AB_1146988, HPA003392: AB_1079942, HPA004636: AB_1079940" "unprognostic (4.08e-1)" "unprognostic (8.66e-2)" "unprognostic (8.08e-2)" "unprognostic (4.22e-2)" "unprognostic (3.06e-2)" "unprognostic (7.74e-3)" "unprognostic (3.37e-2)" "unprognostic (2.83e-1)" "unprognostic (3.05e-1)" "unprognostic (9.53e-2)" "unprognostic (1.03e-1)" "unprognostic (1.61e-1)" "prognostic favorable (9.66e-4)" "unprognostic (8.74e-2)" "unprognostic (7.85e-2)" "unprognostic (4.83e-2)" "unprognostic (1.01e-2)" 18.9 13.4 8.4 9.3 8.3 10.0 11.6 14.9 11.2 14.0 8.9 16.1 7.3 12.4 13.8 15.3 9.9 12.4 18.5 7.5 16.4 13.9 21.5 10.0 7.5 7.7 9.8 10.1 12.6 13.9 9.3 11.9 7.5 13.7 12.6 14.2 10.3 14.1 39.2 11.7 9.7 18.0 6.0 10.4 11.2 20.9 10.7 9.4 13.7 28.5 9.0 14.7 11.6 10.6 33.7 29.2 31.0 22.0 27.4 20.4 25.8 33.0 23.2 24.9 26.3 37.7 22.4 18.4 22.0 23.2 12.6 18.2 33.5 18.1 37.7 17.5 12.3 19.2 19.6 73.6 28.8 15.6 19.8 19.9 20.8 19.5 24.8 23.9 21.5 16.7 22.8 17.8 25.4 21.5 21.3 16.3 15.3 24.1 25.5 15.0 35.5 4.9 39.2 47.7 19.1 15.5 32.8 23.6 17.7 28.4 27.7 14.5 28.0 24.8 21.3 14.7 12.4 15.7 21.4 17.8 12.7 11.2 20.5 4.1 3.5 4.7 3.3 4.3 4.4 3.4 4.2 3.7 3.1 3.2 4.1 4.8 4.3 4.2 3.5 5.7 3.6 1.3 8.4 8.3 14.9 11.2 7.5 16.4 7.7 9.8 7.5 6.0 10.7 10.6 37.1 22.4 22.4 82.3 19.5 98.1 57.5 17.9 23.9 27.2 37.1 25.1 51.7 28.6 22.1 31.3 27.1 22.1 17.5 34.1 11.7 38.9 21.8 32.7 48.0 36.0 31.9 43.8 110.9 26.3 19.9 39.6 20.4 46.9 8.8 21.7 35.0 43.1 12.8 37.0 119.0 18.8 16.2 23.9 45.7 13.4 26.8 22.9 44.4 92.8 18.9 24.6 11.3 102.1 139.2 40.3 13.2 27.8 31.3 49.6 13.2 43.3 25.2 30.2 26.3 52.3 51.9 59.8 53.6 31.4 96.5 33.2 21.4 26.1 16.3 53.6 SVIL ENSG00000197321 Supervillin O95425 10 29457338-29736959 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 808.1;tongue: 581.5" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 204.9;Cardiomyocytes: 469.6;Peritubular cells: 260.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 259.3" "Lineage enriched" "Detected in all" 9 "granulocytes: 259.3" "Cell line enhanced" "Detected in many" "HaCaT: 146.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010878, HPA020095, HPA020138" Approved Supported "Plasma membrane,Actin filaments,Cytosol" NA NA 210000 "Cluster 1: Neutrophils - Mixed function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Actin filaments, Cytosol" "CAB010878: AB_476685, HPA020095: AB_1857680, HPA020138: AB_1857681" "unprognostic (1.11e-1)" "unprognostic (2.94e-1)" "unprognostic (8.06e-2)" "unprognostic (1.15e-2)" "unprognostic (3.47e-3)" "unprognostic (2.26e-2)" "unprognostic (4.12e-1)" "unprognostic (1.49e-1)" "unprognostic (4.28e-1)" "unprognostic (3.42e-3)" "unprognostic (1.55e-1)" "unprognostic (9.20e-2)" "unprognostic (2.38e-3)" "unprognostic (7.11e-3)" "unprognostic (1.51e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (5.70e-5)" 26.4 13.4 3.7 22.7 3.9 37.2 22.6 1.3 8.9 45.8 2.5 314.5 14.8 116.2 24.1 92.1 55.5 52.0 165.0 2.2 2.7 15.4 10.4 22.9 12.6 7.0 4.1 83.3 18.5 31.8 8.5 17.9 4.4 70.3 37.1 10.3 40.6 100.0 808.1 26.9 60.1 107.0 4.4 7.6 77.6 11.7 4.9 19.1 35.0 581.5 10.8 173.2 40.3 5.2 71.4 27.9 12.4 5.4 32.1 84.4 22.1 12.6 24.1 4.3 4.7 34.4 63.1 2.4 43.0 4.9 31.9 146.8 8.6 25.6 5.2 1.4 17.6 0.1 33.6 19.9 21.4 8.0 1.5 72.7 24.5 44.2 19.1 71.9 69.6 14.7 0.1 0.4 6.7 19.9 7.7 4.0 7.0 27.8 15.1 15.5 32.1 0.9 40.2 20.1 18.1 14.1 12.3 1.4 34.3 39.8 12.9 7.9 46.3 21.9 23.4 94.4 34.4 0.6 0.8 0.3 64.5 14.0 65.4 43.4 12.1 58.2 11.1 14.0 10.9 0.6 11.2 7.6 7.3 1.0 17.1 10.9 259.3 14.6 29.6 3.0 4.3 3.7 3.7 3.9 1.3 8.9 2.2 2.7 7.0 4.1 4.4 4.4 4.9 5.2 31.3 48.1 30.5 2.3 3.7 70.2 108.0 41.1 204.9 11.7 36.6 67.1 469.6 18.6 53.5 38.6 25.0 29.7 11.3 39.7 7.9 94.1 4.0 26.3 65.8 61.1 23.9 1.7 8.3 42.3 18.5 68.1 7.7 43.6 10.1 35.7 32.2 11.8 10.4 5.0 43.9 31.3 28.5 7.5 45.7 6.8 109.6 25.3 28.4 146.1 16.7 30.6 13.4 28.1 6.6 63.4 40.2 260.7 3.3 131.8 18.4 10.8 42.2 15.0 46.0 90.6 92.9 6.5 11.1 103.8 60.0 24.8 14.6 27.9 39.2 98.3 SWAP70 "KIAA0640, SWAP-70" ENSG00000133789 "Switching B cell complex subunit SWAP70" Q9UH65 11 9664077-9752993 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 183.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 80.6;naive B-cell: 84.8" "Group enriched" "Detected in all" 7 "B-cells: 84.8;granulocytes: 48.6;monocytes: 29.6" "Cell line enhanced" "Detected in many" "Daudi: 161.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006810, HPA006929" Supported Supported "Plasma membrane,Actin filaments" NA NA 21000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Actin filaments" "HPA006810: AB_1857683, HPA006929: " "unprognostic (4.16e-2)" "unprognostic (7.06e-2)" "unprognostic (2.35e-1)" "unprognostic (3.68e-2)" "unprognostic (1.67e-1)" "unprognostic (3.38e-2)" "unprognostic (3.16e-3)" "unprognostic (1.26e-1)" "unprognostic (4.04e-1)" "unprognostic (3.33e-1)" "unprognostic (1.75e-1)" "unprognostic (3.85e-2)" "unprognostic (2.79e-3)" "unprognostic (5.00e-2)" "unprognostic (1.14e-1)" "unprognostic (3.61e-1)" "unprognostic (1.44e-1)" 39.3 10.4 12.8 37.5 13.7 20.9 31.9 13.6 15.9 22.6 17.2 15.0 15.4 17.8 10.4 17.8 16.3 22.0 16.2 12.2 14.1 17.2 10.0 24.9 66.1 16.7 13.6 10.2 15.0 19.4 5.7 39.0 16.7 14.1 12.8 3.9 18.0 15.3 9.8 26.4 20.3 19.7 16.5 59.5 15.9 4.8 14.3 17.3 22.3 14.7 75.3 31.2 17.6 16.5 40.6 22.2 30.8 0.1 62.9 54.6 54.0 43.4 52.6 40.3 44.1 24.7 31.3 161.0 41.6 83.5 57.9 47.7 37.9 24.2 51.6 14.8 15.2 42.6 25.7 12.1 35.2 33.3 76.2 38.4 29.6 29.5 52.3 32.6 124.4 20.2 3.9 0.6 42.4 6.4 10.0 16.1 28.4 10.7 11.3 23.6 28.9 4.7 33.6 106.1 1.5 15.5 41.3 52.6 35.2 42.9 20.9 25.1 143.6 70.3 25.1 59.4 41.2 4.2 12.4 111.5 27.9 36.6 29.3 19.7 5.7 48.6 1.2 13.5 0.5 80.6 1.4 1.1 8.2 84.8 1.2 1.3 1.1 7.9 29.6 2.3 4.2 5.4 12.8 13.7 13.6 15.9 12.2 14.1 16.7 13.6 16.7 16.5 14.3 16.5 154.0 67.3 60.8 33.0 183.7 35.6 68.1 40.1 36.5 3.4 35.1 28.3 17.6 22.8 57.7 20.2 0.0 82.6 9.9 11.3 13.7 47.4 1.6 66.5 18.6 136.0 13.1 9.7 9.0 21.6 128.0 39.1 15.8 71.6 137.8 10.3 53.2 7.2 65.0 26.9 14.5 8.7 18.3 61.9 50.8 2.9 29.8 58.5 28.4 77.8 88.8 9.2 6.2 22.1 22.4 37.0 15.1 34.6 20.7 63.0 22.4 11.7 50.9 2.3 19.7 46.2 35.5 5.5 10.8 17.4 31.3 140.1 15.5 33.4 9.0 78.8 SYNPO KIAA1029 ENSG00000171992 Synaptopodin Q8N3V7 5 150601080-150659207 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 369.6;skeletal muscle: 1296.3;tongue: 502.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 264.7;Distal enterocytes: 70.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Lineage enriched" "Detected in single" 10 "B-cells: 1.0" "Cell line enhanced" "Detected in many" "BEWO: 88.4;EFO-21: 72.8;HUVEC TERT2: 72.7;TIME: 178.0;U-87 MG: 152.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033265, HPA034631, CAB037325, HPA071347" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "Actin filaments" "CAB033265: AB_2201163, CAB037325: , HPA034631: AB_10669994, HPA071347: AB_2732179" "unprognostic (2.09e-2)" "unprognostic (7.72e-3)" "unprognostic (3.95e-2)" "unprognostic (2.78e-3)" "unprognostic (3.07e-2)" "unprognostic (1.66e-2)" "unprognostic (1.76e-1)" "unprognostic (1.41e-2)" "unprognostic (1.90e-1)" "unprognostic (1.21e-1)" "unprognostic (1.17e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (1.53e-6)" "unprognostic (1.23e-1)" "unprognostic (5.72e-2)" "unprognostic (2.21e-2)" "unprognostic (6.35e-2)" 91.8 112.1 103.5 21.3 60.7 0.3 48.6 0.0 88.9 23.2 0.8 37.4 31.4 38.7 20.9 31.0 30.8 32.2 369.6 91.2 5.2 60.6 38.5 72.1 10.6 18.2 8.5 34.6 32.9 17.1 21.6 23.8 5.2 46.0 17.5 10.0 21.6 29.1 1296.3 15.4 39.6 38.9 20.6 38.9 34.9 17.0 5.1 6.6 31.1 502.1 11.1 56.8 22.3 34.9 0.5 24.2 0.2 0.3 3.5 3.2 88.4 13.8 18.9 4.6 3.7 21.6 9.7 0.1 72.8 19.9 29.2 8.9 0.1 13.5 1.9 0.2 0.2 0.0 37.4 4.7 19.6 0.0 0.9 3.7 21.3 5.2 3.7 27.5 72.7 0.2 0.2 0.2 4.4 1.6 0.1 0.7 2.8 9.3 11.6 0.5 0.7 0.2 3.4 1.9 8.5 39.3 19.9 21.6 0.7 31.1 1.6 6.6 178.0 17.4 53.2 0.4 3.6 0.8 0.2 1.3 152.5 0.3 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 103.5 60.7 0.0 88.9 91.2 5.2 18.2 8.5 5.2 20.6 5.1 34.9 51.1 35.3 12.2 1.3 4.8 4.6 3.0 32.6 1.8 1.9 6.4 2.5 264.7 27.1 17.0 7.3 2.1 14.8 0.5 70.5 0.0 43.7 1.7 0.4 0.4 56.3 13.8 2.7 22.5 34.5 6.0 19.9 4.6 0.5 0.0 40.9 62.8 40.0 2.1 0.0 5.7 8.4 2.0 10.8 5.1 3.4 2.8 0.9 5.4 6.5 24.0 7.2 0.0 2.5 1.3 35.6 24.4 27.8 0.6 5.7 52.6 4.4 7.6 0.8 46.0 18.0 29.2 1.2 0.8 1.4 2.3 25.9 1.6 8.6 11.8 3.6 SYNPO2 MYOPODIN ENSG00000172403 "Synaptopodin 2" Q9UMS6 4 118850688-119061247 "Predicted intracellular proteins" "Actin-binding, Muscle protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 991.6;tongue: 493.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 135.4;Endometrial stromal cells: 130.0;Excitatory neurons: 149.6;Peritubular cells: 101.5;Sertoli cells: 131.5;Skeletal myocytes: 93.4;Smooth muscle cells: 206.1" "Group enriched" "Detected in all" 5 "prostate cancer: 25.7;stomach cancer: 27.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 57.8;LHCN-M2: 18.5;SH-SY5Y: 83.2" "Region enriched" "Detected in all" 4 "thalamus: 27.1" "Low region specificity" "Detected in all" "HPA030665, CAB037231, HPA049707, HPA068563" Enhanced Enhanced "Vesicles,Actin filaments" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Vesicles, Actin filaments" "CAB037231: AB_262098, HPA030665: AB_10696210, HPA049707: AB_2680857, HPA068563: AB_2686006" "unprognostic (1.50e-2)" "unprognostic (1.73e-2)" "unprognostic (5.32e-2)" "unprognostic (1.50e-2)" "unprognostic (1.81e-1)" "unprognostic (2.39e-1)" "unprognostic (5.71e-4)" "unprognostic (2.18e-1)" "unprognostic (3.07e-1)" "unprognostic (3.52e-1)" "unprognostic (1.39e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (5.67e-5)" "unprognostic (1.82e-2)" "unprognostic (1.35e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (3.91e-4)" 57.5 10.8 6.1 47.4 7.9 0.3 35.9 4.1 5.7 55.0 2.2 346.4 34.3 137.1 33.4 197.1 89.5 50.0 66.8 10.7 13.3 8.7 7.0 16.2 10.5 5.4 7.5 39.0 3.8 3.6 7.5 20.8 6.1 180.5 58.0 1.2 16.0 267.4 991.6 17.9 75.5 244.4 9.2 10.2 126.2 6.7 5.8 14.3 16.0 493.5 6.5 226.5 54.0 12.0 0.2 4.2 0.2 0.0 10.5 3.5 0.7 13.4 14.1 0.4 0.5 0.0 0.7 1.5 0.1 57.8 0.9 0.2 0.4 0.3 0.7 5.9 0.1 0.8 1.3 0.0 2.4 0.1 0.2 14.5 0.3 4.0 0.2 3.7 0.2 0.2 0.0 0.7 18.5 0.3 0.7 7.2 1.4 0.0 0.0 0.5 1.5 0.4 0.2 0.3 0.4 83.2 0.4 0.3 0.1 3.3 0.0 7.0 0.4 0.6 0.1 0.2 0.1 0.1 0.3 0.1 1.1 0.6 0.2 0.8 0.1 0.5 0.2 0.0 0.4 0.3 0.4 0.2 0.0 0.4 0.4 0.3 0.2 0.3 0.1 0.0 0.5 0.1 6.1 7.9 4.1 5.7 10.7 13.3 5.4 7.5 6.1 9.2 5.8 12.0 25.5 3.2 1.1 42.7 1.1 13.5 17.9 3.7 46.1 2.5 6.3 30.7 135.4 0.0 0.3 1.8 0.0 1.4 0.5 0.1 0.0 0.1 2.2 6.9 130.0 11.3 0.0 1.7 149.6 1.8 0.5 41.5 0.5 10.6 0.0 16.1 13.9 0.4 1.4 0.0 31.5 0.2 0.0 0.9 11.4 7.0 27.1 3.8 5.4 76.8 12.9 0.0 0.0 6.0 3.0 0.2 0.4 101.5 0.8 24.9 0.1 0.3 2.5 0.5 131.5 93.4 206.1 1.3 0.5 5.3 8.1 0.8 2.6 33.4 0.2 4.0 SZT2 "C1orf84, FLJ10387, FLJ34502, KIAA0467, RP11-506B15.1, SZT2A, SZT2B" ENSG00000198198 "SZT2 subunit of KICSTOR complex" Q5T011 1 43389882-43454247 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 62.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029012 Approved Approved "Nucleoplasm,Vesicles,Actin filaments" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 20: HeLa - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Vesicles, Actin filaments" "HPA029012: AB_10600817" "unprognostic (1.35e-1)" "unprognostic (2.55e-1)" "unprognostic (4.14e-1)" "unprognostic (6.61e-2)" "unprognostic (1.29e-1)" "prognostic favorable (1.47e-7)" "prognostic unfavorable (2.53e-4)" "prognostic favorable (6.20e-4)" "unprognostic (1.54e-1)" "unprognostic (1.81e-2)" "unprognostic (5.96e-2)" "unprognostic (1.03e-1)" "unprognostic (1.05e-2)" "unprognostic (1.84e-3)" "unprognostic (8.28e-2)" "unprognostic (7.19e-2)" "unprognostic (2.61e-2)" 6.3 5.3 1.3 4.3 2.5 6.0 6.2 3.2 3.1 6.1 0.8 6.7 3.4 7.2 2.6 5.9 7.0 2.7 5.4 1.1 2.1 4.7 4.4 6.4 4.2 2.9 2.3 8.0 6.5 5.6 8.8 2.7 2.5 6.5 3.4 4.0 6.5 3.2 6.6 7.7 7.9 3.6 0.9 7.1 6.4 9.6 3.0 4.4 9.0 3.9 4.1 6.2 5.8 5.0 4.5 4.4 3.7 3.4 9.1 4.5 5.7 3.7 4.4 4.5 4.1 1.5 5.0 4.1 4.1 5.9 3.2 5.1 3.7 6.3 3.9 5.1 3.4 7.5 8.1 2.7 3.4 6.1 6.2 4.8 4.2 7.7 7.5 5.0 5.2 4.7 3.4 6.8 3.2 2.1 4.1 1.6 3.3 2.7 4.5 4.5 5.1 4.9 2.6 6.2 3.8 3.4 7.8 5.9 4.0 4.8 3.2 8.8 6.5 4.8 6.8 6.4 6.5 7.3 2.8 3.4 4.9 3.8 3.1 1.4 0.5 1.4 0.3 0.4 0.8 0.3 0.1 0.1 0.4 0.3 0.4 0.3 1.1 0.3 0.5 0.9 0.4 0.2 1.3 2.5 3.2 3.1 1.1 2.1 2.9 2.3 2.5 0.9 3.0 5.0 8.3 25.6 19.3 19.6 10.5 1.9 3.5 5.1 6.2 16.8 7.7 7.0 4.8 5.7 6.8 5.5 62.6 6.5 9.2 10.0 0.0 6.1 14.2 5.8 10.1 7.6 3.6 5.5 20.4 6.4 5.2 7.0 13.7 6.9 14.5 19.0 12.8 13.1 5.4 13.5 20.2 7.0 4.1 7.0 3.1 15.8 9.3 9.4 5.4 15.9 11.6 5.8 13.4 11.1 29.1 6.8 3.7 6.0 9.5 4.2 10.5 9.2 8.0 22.2 19.7 9.1 7.1 8.1 8.6 4.2 1.8 5.5 11.4 12.6 7.0 3.8 TAGLN2 "HA1756, KIAA0120" ENSG00000158710 "Transgelin 2" P37802 1 159918107-159925507 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 2404.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA001925 Approved Approved "Actin filaments,Cytosol" "Intracellular and membrane" NA NA 270000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "Actin filaments" "HPA001925: AB_1857756" "prognostic unfavorable (2.06e-5)" "unprognostic (2.56e-1)" "unprognostic (4.05e-2)" "unprognostic (1.27e-1)" "unprognostic (3.69e-2)" "unprognostic (8.06e-2)" "prognostic unfavorable (7.07e-5)" "unprognostic (4.61e-2)" "unprognostic (1.50e-1)" "unprognostic (3.21e-1)" "unprognostic (3.56e-3)" "unprognostic (2.34e-1)" "prognostic unfavorable (1.92e-10)" "unprognostic (1.81e-1)" "unprognostic (9.22e-2)" "unprognostic (3.95e-2)" "unprognostic (2.50e-2)" 401.9 154.7 103.7 356.0 103.2 437.3 355.4 106.3 115.0 266.6 94.9 337.4 314.3 220.5 94.9 494.0 231.9 282.6 351.1 101.1 152.7 307.9 254.4 687.7 321.1 141.7 117.6 170.9 284.7 81.0 100.0 378.2 122.9 208.5 307.9 46.1 388.7 205.2 83.4 418.2 356.3 254.4 125.2 479.7 698.8 127.0 125.9 309.6 210.2 139.6 386.4 436.1 350.0 114.9 1382.3 723.7 22.3 8.3 266.8 646.6 835.4 760.0 872.6 1635.2 799.8 786.6 1049.3 862.0 628.0 954.9 495.0 1054.3 378.1 1039.9 978.8 974.3 355.5 1140.7 651.8 50.0 322.7 808.2 1221.4 667.4 776.9 1030.4 504.3 1134.7 1029.0 260.3 494.8 578.9 586.1 563.0 378.1 601.2 619.3 947.6 1457.7 2.9 391.7 1275.3 376.6 527.7 340.7 325.6 900.7 1435.1 410.3 1190.6 756.5 814.2 1147.3 955.1 1134.4 876.9 2078.0 230.8 110.6 525.0 1238.3 541.3 603.8 1458.4 742.0 3160.6 558.9 449.7 499.9 866.5 620.0 544.6 1177.7 680.2 321.6 360.3 3746.8 817.6 356.9 1966.4 756.1 2257.9 103.7 103.2 106.3 115.0 101.1 152.7 141.7 117.6 122.9 125.2 125.9 114.9 617.1 179.5 130.5 0.3 507.8 549.1 330.6 454.3 307.9 31.6 257.0 201.8 12.8 121.5 221.4 183.9 18.8 497.4 567.6 371.0 74.3 1273.4 54.3 289.4 145.9 509.6 317.8 197.6 0.1 1206.9 2404.5 405.2 545.3 242.7 418.8 32.0 265.2 64.1 443.7 3.3 0.6 445.5 284.8 285.9 952.4 85.9 118.7 651.5 334.4 16.9 911.4 66.3 186.4 0.5 1.6 877.4 263.2 63.9 393.4 337.5 324.2 208.2 275.9 25.6 184.1 358.3 324.3 14.3 20.7 494.1 572.5 230.4 393.6 136.7 271.7 405.9 TARS1 TARS ENSG00000113407 "Threonyl-tRNA synthetase 1" P26639 5 33440696-33468091 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 63.4;Cytotrophoblasts: 36.6;dendritic cells: 15.9;Extravillous trophoblasts: 42.1;Hofbauer cells: 32.1;Syncytiotrophoblasts: 52.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037425 Approved Approved "Actin filaments,Cytosol" NA NA 580000 "Cluster 15: NK-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Actin filaments" "HPA037425: AB_10672279" "prognostic unfavorable (6.14e-5)" "unprognostic (5.13e-2)" "unprognostic (9.04e-2)" "prognostic unfavorable (5.17e-4)" "unprognostic (9.10e-2)" "unprognostic (1.07e-3)" "prognostic unfavorable (9.88e-7)" "unprognostic (1.43e-1)" "unprognostic (1.61e-1)" "unprognostic (2.65e-3)" "unprognostic (5.97e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (9.63e-4)" "unprognostic (1.37e-1)" "unprognostic (5.15e-2)" "unprognostic (1.18e-1)" "unprognostic (7.25e-2)" 29.0 32.2 13.7 33.8 16.2 45.0 26.8 20.0 20.1 24.0 17.1 42.6 30.7 24.7 35.8 40.9 17.4 19.9 38.7 13.8 17.9 32.4 68.6 24.1 29.9 22.4 18.5 17.9 68.1 33.8 9.9 37.1 18.3 27.6 42.8 40.7 36.8 26.4 38.4 19.1 29.8 37.2 18.4 21.7 40.0 18.7 18.3 31.7 37.6 28.4 40.1 42.9 10.8 22.6 253.0 136.1 132.7 189.5 80.2 129.9 230.1 237.5 172.9 152.5 163.7 176.6 128.7 96.0 84.8 176.5 271.8 151.1 261.1 207.1 267.4 158.9 140.5 151.1 332.9 108.5 256.7 225.6 141.0 133.7 287.7 217.5 273.9 102.4 144.3 191.8 236.3 204.6 191.5 105.7 166.3 104.7 159.2 181.5 168.4 137.1 237.9 123.4 170.8 119.8 81.0 102.7 245.6 175.8 195.5 103.8 85.9 236.3 123.0 132.8 211.9 102.5 196.3 135.4 258.4 132.6 156.2 302.6 148.3 34.2 22.0 22.6 27.4 24.5 27.6 28.7 25.2 26.6 32.6 23.9 21.5 27.5 2.6 46.2 18.3 18.3 24.2 20.6 13.7 16.2 20.0 20.1 13.8 17.9 22.4 18.5 18.3 18.4 18.3 22.6 12.5 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 63.4 0.0 0.0 0.0 0.0 36.6 15.9 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 42.1 11.7 0.0 0.0 0.0 0.0 0.0 0.0 32.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 52.1 2.6 0.0 0.0 0.0 TAS2R10 "T2R10, TRB2" ENSG00000121318 "Taste 2 receptor member 10" Q9NYW0 12 10825317-10826358 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Astrocytes: 6.2;Excitatory neurons: 14.4;Inhibitory neurons: 14.4;Microglial cells: 4.7;Oligodendrocyte precursor cells: 14.1;Oligodendrocytes: 11.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA070201 Approved "Vesicles,Plasma membrane,Actin filaments" NA NA "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Plasma membrane" "Actin filaments" "HPA070201: " "unprognostic (1.28e-1)" "unprognostic (3.89e-4)" "unprognostic (1.77e-1)" "unprognostic (1.82e-2)" "unprognostic (1.10e-1)" "unprognostic (5.82e-3)" "unprognostic (3.86e-1)" "unprognostic (7.72e-2)" "unprognostic (5.27e-2)" "unprognostic (1.67e-1)" "unprognostic (1.24e-2)" "unprognostic (1.20e-1)" "unprognostic (4.16e-5)" "unprognostic (5.41e-2)" "unprognostic (3.18e-2)" "unprognostic (2.87e-2)" "unprognostic (2.56e-3)" 0.2 0.6 0.1 0.0 0.1 0.0 0.2 0.1 0.4 0.3 0.0 0.2 0.0 0.4 0.1 0.1 0.1 0.0 0.2 0.1 0.0 0.2 0.3 0.2 0.0 0.1 0.1 0.3 0.2 0.0 0.4 0.0 0.1 0.2 0.0 0.3 0.4 0.0 0.0 0.1 0.3 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.0 0.0 0.0 6.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 14.4 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.7 0.0 0.1 0.0 14.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 14.1 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 TAS2R42 "hT2R55, T2R24, T2R55, TAS2R55" ENSG00000186136 "Taste 2 receptor member 42" Q7RTR8 12 11185993-11186937 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA036149 Uncertain Approved "Nucleoplasm,Actin filaments,Focal adhesion sites" NA NA "Nucleoplasm, Actin filaments" "Focal adhesion sites" "HPA036149: AB_10672080" "unprognostic (2.45e-2)" "unprognostic (4.17e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TAX1BP3 TIP-1 ENSG00000213977 "Tax1 binding protein 3" O14907 17 3662895-3668679 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 395.9;Ductal cells: 351.0;Exocrine glandular cells: 385.9;Pancreatic endocrine cells: 505.8;Paneth cells: 362.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 164.3;granulocytes: 217.8;monocytes: 78.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046410, HPA063078" Approved Approved "Nucleoli fibrillar center,Vesicles,Actin filaments" NA NA 120000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli fibrillar center" "Vesicles, Actin filaments" "HPA046410: AB_2679656, HPA063078: AB_2684937" "unprognostic (6.15e-2)" "unprognostic (6.46e-3)" "unprognostic (3.37e-1)" "unprognostic (1.32e-1)" "prognostic unfavorable (2.17e-4)" "unprognostic (1.68e-1)" "unprognostic (1.12e-3)" "prognostic unfavorable (1.76e-4)" "unprognostic (1.80e-2)" "unprognostic (5.45e-3)" "unprognostic (5.19e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (7.90e-4)" "unprognostic (5.12e-2)" "unprognostic (2.10e-1)" "unprognostic (2.10e-3)" "unprognostic (1.92e-1)" 107.3 131.8 62.7 49.2 78.5 16.5 94.4 67.9 67.3 192.9 48.2 108.5 108.8 128.1 33.6 258.5 84.4 90.9 194.8 57.3 58.8 115.0 39.7 94.9 39.3 72.5 73.3 95.9 80.4 23.5 30.9 53.2 69.9 91.7 77.4 3.7 109.7 105.6 28.7 120.4 119.6 70.3 66.2 52.3 136.5 51.2 65.2 44.6 63.6 33.4 49.0 102.8 160.1 80.6 183.1 319.1 68.4 38.5 219.2 175.6 81.3 223.6 184.5 234.0 136.7 135.9 144.5 19.1 159.1 290.8 77.2 282.6 39.1 205.3 90.8 50.7 64.4 25.9 75.8 106.6 191.1 4.3 37.7 267.6 322.5 145.1 68.9 165.3 266.0 50.1 9.6 14.4 280.1 169.4 52.2 15.1 65.9 116.7 112.6 50.0 41.8 16.3 248.6 141.2 14.7 43.2 276.2 116.2 39.4 67.5 125.3 23.2 269.6 195.3 75.2 154.9 230.2 5.7 2.6 5.5 117.4 30.0 190.3 217.8 65.4 120.4 26.9 78.9 22.2 29.2 25.0 26.6 58.7 25.3 17.3 22.7 73.8 20.0 73.6 164.3 36.7 53.3 62.7 78.5 67.9 67.3 57.3 58.8 72.5 73.3 69.9 66.2 65.2 80.6 51.5 60.9 25.8 0.0 19.0 95.3 79.7 229.3 99.6 1.6 51.0 28.2 41.5 92.9 107.6 99.3 0.0 124.7 68.5 395.9 88.0 351.0 16.2 12.8 27.3 77.0 24.6 21.4 0.0 385.9 145.3 72.6 43.8 16.1 26.6 21.2 75.3 11.1 69.8 5.0 0.0 120.0 71.2 35.2 73.2 10.5 174.6 64.0 113.8 0.0 85.5 19.8 26.8 0.0 0.0 505.8 362.8 209.9 5.8 89.0 279.2 185.3 26.8 2.6 39.5 44.1 78.6 8.6 12.8 94.5 76.0 155.6 16.1 92.0 103.0 107.9 TCTN1 "FLJ21127, JBTS13, TECT1" ENSG00000204852 "Tectonic family member 1" Q2MV58 12 110614027-110663431 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 98.9;Respiratory ciliated cells: 203.7;Spermatocytes: 96.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 34.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039687, HPA040036" Approved Approved "Nucleoplasm,Vesicles,Actin filaments,Microtubules" "Intracellular and membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Actin filaments" "Nucleoplasm, Vesicles, Microtubules" "HPA039687: AB_10795293, HPA040036: AB_10794759" "unprognostic (2.54e-1)" "unprognostic (7.22e-3)" "unprognostic (2.28e-1)" "prognostic favorable (1.13e-5)" "unprognostic (2.89e-2)" "unprognostic (6.53e-2)" "unprognostic (2.11e-1)" "unprognostic (3.05e-2)" "unprognostic (6.02e-2)" "unprognostic (4.54e-2)" "unprognostic (5.20e-3)" "unprognostic (9.60e-2)" "unprognostic (9.97e-2)" "unprognostic (2.15e-2)" "unprognostic (8.41e-2)" "unprognostic (1.24e-1)" "unprognostic (4.27e-2)" 8.8 14.0 5.6 2.0 5.3 1.0 8.4 9.3 7.5 10.1 18.2 7.1 1.5 9.0 10.7 4.5 15.3 5.6 17.0 5.7 4.5 19.0 9.1 8.3 2.5 4.5 5.0 12.8 10.8 15.2 26.2 4.0 4.4 10.0 0.9 3.0 9.5 6.1 10.3 5.3 4.0 3.6 3.6 4.6 6.9 21.1 5.2 1.3 17.6 1.9 0.8 7.7 7.0 7.0 11.6 11.7 6.7 17.6 24.9 18.0 4.3 6.3 16.2 5.9 4.4 1.2 2.7 2.0 6.9 18.6 7.2 6.1 4.7 4.6 5.0 4.7 8.7 0.3 4.1 3.6 8.6 1.2 1.3 14.8 7.8 7.7 7.9 34.7 3.3 3.0 7.4 2.5 9.7 9.4 0.9 2.2 4.1 3.5 16.7 2.4 2.9 14.6 16.8 1.8 5.5 11.7 13.1 1.6 5.3 5.5 22.7 16.0 4.0 8.2 2.4 3.5 6.0 4.2 2.6 2.6 11.1 1.3 9.3 0.0 2.0 0.0 0.8 3.6 2.2 4.9 1.5 2.5 3.4 9.1 2.2 1.6 6.4 1.0 1.9 4.3 0.5 2.0 5.6 5.3 9.3 7.5 5.7 4.5 4.5 5.0 4.4 3.6 5.2 7.0 6.5 3.2 18.8 25.5 24.0 13.8 28.4 38.4 18.2 10.7 22.8 19.3 13.0 24.3 26.0 16.5 31.3 30.9 5.8 1.0 9.8 24.3 82.7 98.9 29.0 11.5 18.0 1.3 15.0 4.7 8.5 30.5 8.2 9.8 3.8 27.1 9.3 6.9 11.8 3.3 12.1 4.8 32.6 3.8 12.4 18.7 17.1 7.0 23.2 7.5 1.7 30.5 0.0 12.5 9.3 4.2 2.4 28.6 9.6 20.0 0.4 42.5 203.7 34.1 6.6 16.2 18.3 96.9 30.1 8.5 11.2 18.3 4.2 38.1 4.7 16.6 TEKT5 "CT149, FLJ32871" ENSG00000153060 "Tektin 5" Q96M29 16 10627501-10694930 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 32 "testis: 32.1" "Group enriched" "Detected in some" 75 "Early spermatids: 490.7;Late spermatids: 169.6" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 13 "BEWO: 12.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA043578 Approved "Actin filaments" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 29: Early spermatids - Spermatogenesis" "Actin filaments" "HPA043578: AB_10795772" "unprognostic (5.90e-2)" "unprognostic (1.37e-2)" "unprognostic (1.39e-2)" "unprognostic (7.53e-2)" "unprognostic (2.69e-2)" "unprognostic (9.76e-2)" "unprognostic (2.00e-1)" "unprognostic (1.39e-2)" "unprognostic (1.89e-1)" "unprognostic (5.09e-2)" "unprognostic (5.88e-2)" "unprognostic (5.02e-2)" "unprognostic (3.24e-7)" "unprognostic (3.80e-2)" "unprognostic (2.31e-1)" "unprognostic (3.76e-2)" "unprognostic (8.12e-5)" 0.0 0.1 0.2 0.0 0.2 0.0 0.1 0.0 0.7 0.0 0.1 0.3 0.0 0.0 0.4 0.1 0.1 0.1 0.1 0.3 0.0 0.1 0.9 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.2 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.1 1.0 32.1 0.1 0.0 0.1 0.0 0.2 0.6 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.4 0.1 0.7 0.2 0.3 0.1 0.0 0.1 0.9 0.2 0.0 0.2 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.7 0.3 0.0 0.1 0.1 0.2 0.0 0.1 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 3.0 1.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 490.7 0.1 0.0 0.2 1.8 0.0 4.4 0.0 0.0 0.0 2.6 0.1 0.0 0.8 0.0 0.2 0.0 0.0 4.2 0.0 0.0 0.0 0.0 169.6 4.1 0.7 0.0 1.9 0.0 0.0 0.0 1.5 0.8 0.1 0.0 2.2 0.1 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.1 3.3 1.3 0.0 0.3 0.0 0.0 0.1 0.1 0.3 TIGD6 DKFZp761E2110 ENSG00000164296 "Tigger transposable element derived 6" Q17RP2 5 149993118-150000654 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 20.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA044599 Uncertain Approved "Nucleoplasm,Vesicles,Actin filaments" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Vesicles, Actin filaments" "HPA044599: AB_10961286" "unprognostic (1.06e-1)" "unprognostic (3.25e-1)" "prognostic favorable (5.35e-4)" "unprognostic (1.94e-2)" "unprognostic (8.18e-2)" "unprognostic (3.00e-2)" "unprognostic (1.30e-3)" "unprognostic (7.48e-2)" "unprognostic (5.96e-2)" "unprognostic (3.85e-2)" "prognostic favorable (5.88e-4)" "unprognostic (1.94e-3)" "unprognostic (1.85e-3)" "unprognostic (1.55e-2)" "unprognostic (1.46e-1)" "unprognostic (1.33e-3)" "unprognostic (1.18e-1)" 2.6 3.6 2.1 1.7 2.4 1.3 4.7 2.7 2.4 2.5 2.6 2.8 2.2 2.4 5.1 1.7 3.1 2.3 2.0 2.0 2.3 3.6 2.8 2.4 1.9 2.2 2.3 3.9 3.2 11.2 2.6 2.6 2.2 4.1 2.5 3.5 3.1 3.0 1.4 2.7 2.0 2.6 2.1 2.1 2.9 4.0 2.2 2.3 3.0 2.2 2.0 2.4 1.7 2.5 2.1 5.7 3.8 8.2 10.7 8.8 5.9 6.0 6.3 4.6 4.6 3.7 3.7 1.0 5.3 7.1 5.7 3.7 3.4 4.4 5.4 4.7 2.8 1.8 3.1 2.0 9.5 2.6 4.4 9.0 8.3 5.9 7.7 5.4 3.6 4.1 2.5 4.7 5.8 5.0 3.4 1.2 1.5 2.7 4.8 3.9 4.3 2.7 4.4 3.0 2.9 3.8 4.2 6.7 9.1 4.6 7.5 4.5 4.9 3.7 2.8 4.1 4.5 3.5 1.4 2.7 5.9 2.8 5.9 0.0 2.2 1.2 1.5 2.3 1.3 1.4 2.0 1.5 1.9 1.7 4.2 2.6 0.0 3.4 1.3 1.0 2.2 1.5 2.1 2.4 2.7 2.4 2.0 2.3 2.2 2.3 2.2 2.1 2.2 2.5 3.1 12.8 2.7 1.3 2.2 2.2 6.6 2.9 2.2 6.2 5.4 3.7 5.4 4.3 4.7 3.7 0.0 5.2 2.6 2.0 7.9 5.1 1.2 2.9 3.5 2.7 3.0 0.4 1.4 4.7 2.7 3.5 7.1 3.6 3.8 4.6 3.3 1.8 4.2 3.3 1.6 2.6 6.1 1.9 1.9 2.1 4.4 2.6 3.6 2.8 4.8 6.3 1.0 4.5 5.6 4.3 1.9 3.4 3.8 5.7 3.1 7.9 3.6 6.3 0.0 2.1 3.8 20.0 8.7 2.6 1.1 3.6 2.2 6.8 2.0 4.9 TMEM17 FLJ34583 ENSG00000186889 "Transmembrane protein 17" Q86X19 2 62500218-62511894 "Predicted membrane proteins, Transporters" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 25.4;Spermatocytes: 39.2;Spermatogonia: 21.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.9" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018100 Uncertain Approved "Actin filaments" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 17: WM-115 - Nervous system development" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Actin filaments" "HPA018100: AB_2240686" "unprognostic (8.09e-2)" "unprognostic (8.43e-2)" "unprognostic (2.11e-1)" "unprognostic (1.14e-1)" "unprognostic (5.02e-3)" "unprognostic (3.78e-1)" "unprognostic (1.87e-4)" "unprognostic (1.21e-1)" "unprognostic (1.47e-1)" "unprognostic (3.44e-2)" "unprognostic (2.26e-1)" "unprognostic (2.36e-1)" "unprognostic (7.68e-3)" "unprognostic (1.11e-2)" "unprognostic (3.06e-2)" "unprognostic (3.62e-1)" "unprognostic (1.49e-6)" 2.4 5.0 4.1 0.5 4.3 0.8 2.4 2.6 4.2 1.8 4.8 1.4 1.0 2.3 1.6 2.6 4.3 2.9 2.2 4.4 9.5 4.3 2.3 1.8 1.0 4.5 5.5 3.1 3.2 6.1 4.3 1.7 5.5 2.5 0.9 4.0 2.2 2.0 1.8 2.4 0.8 1.6 3.5 0.8 1.3 4.8 8.5 1.4 4.6 1.8 0.9 1.5 1.3 3.4 3.3 4.6 4.7 1.8 2.4 3.1 3.0 2.5 2.3 2.0 2.1 0.3 6.1 0.0 3.2 3.3 6.7 3.2 2.1 1.4 1.5 3.2 1.4 1.5 1.8 0.3 3.5 2.3 1.8 2.8 3.9 1.7 3.9 3.4 2.5 0.3 1.4 0.2 5.3 0.9 0.4 0.5 2.3 3.0 2.3 0.2 0.6 0.2 4.3 1.0 1.2 4.0 2.6 0.9 9.1 1.6 1.5 3.0 1.7 4.0 2.2 4.8 2.6 0.4 0.0 0.0 5.8 0.4 8.4 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.2 0.5 0.3 0.1 1.9 0.0 0.4 4.1 4.3 2.6 4.2 4.4 9.5 4.5 5.5 5.5 3.5 8.5 3.4 2.9 3.2 4.1 2.6 0.4 5.0 2.3 10.7 9.1 7.1 3.0 2.8 2.6 4.3 7.5 5.5 8.4 2.3 1.5 0.1 0.0 5.3 4.8 11.4 2.1 2.7 1.2 1.7 2.8 8.5 2.2 4.2 1.1 1.7 1.3 2.8 3.9 2.5 2.6 10.1 3.9 0.9 6.1 0.6 1.5 2.8 4.7 1.4 3.6 1.0 0.9 9.9 0.0 0.0 2.9 7.9 0.3 3.8 1.4 1.0 0.4 2.5 25.4 4.8 6.6 2.4 1.8 39.2 21.7 5.5 2.8 0.4 0.3 5.4 1.1 1.5 TMEM50A SMP1 ENSG00000183726 "Transmembrane protein 50A" O95807 1 25338317-25362361 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065192 Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "Actin filaments, Cytosol" "HPA065192: AB_2685429" "unprognostic (2.41e-2)" "unprognostic (2.74e-1)" "unprognostic (5.17e-3)" "prognostic favorable (8.64e-5)" "unprognostic (1.45e-1)" "unprognostic (2.04e-2)" "prognostic unfavorable (3.34e-4)" "unprognostic (7.39e-2)" "unprognostic (7.92e-3)" "unprognostic (2.53e-1)" "unprognostic (1.02e-2)" "unprognostic (2.44e-2)" "unprognostic (2.39e-3)" "unprognostic (6.66e-2)" "unprognostic (2.91e-1)" "unprognostic (3.91e-3)" "unprognostic (3.44e-2)" 47.2 63.0 43.9 44.5 47.8 41.8 55.5 45.3 55.8 47.0 43.7 58.5 49.6 35.7 53.0 36.5 38.4 45.7 44.2 45.0 44.4 55.0 33.4 58.1 52.2 46.5 44.4 26.2 32.6 49.5 14.6 57.7 46.4 54.4 65.7 45.4 81.5 52.7 16.9 41.1 55.4 46.0 47.2 46.9 49.5 16.1 45.5 47.1 47.0 26.5 47.3 55.1 29.8 50.4 43.3 44.6 74.3 42.3 132.9 119.8 28.1 89.0 123.6 143.4 159.5 36.5 110.9 50.2 47.9 274.6 55.7 62.6 56.3 61.9 161.2 126.1 81.4 104.7 47.5 55.2 96.5 82.4 80.3 128.0 91.4 106.1 60.5 69.7 107.0 50.8 73.1 79.5 140.9 30.6 53.2 90.2 90.6 73.7 37.1 45.7 85.3 88.9 148.8 30.9 64.5 42.3 89.0 64.2 72.2 69.3 32.7 52.0 171.0 86.5 36.6 144.9 36.8 52.3 61.5 45.0 117.1 117.2 50.3 275.5 76.9 109.8 87.9 94.7 91.9 49.6 77.2 91.1 55.9 40.9 55.1 76.6 159.2 80.5 117.3 51.9 95.4 106.3 43.9 47.8 45.3 55.8 45.0 44.4 46.5 44.4 46.4 47.2 45.5 50.4 244.8 144.2 84.2 21.2 107.9 253.4 184.5 392.3 146.8 43.9 162.0 164.8 105.6 102.9 212.7 169.2 27.1 108.9 191.0 175.6 50.9 300.3 25.4 136.4 119.3 203.3 83.0 93.6 31.6 215.6 312.5 198.1 91.3 180.8 126.6 58.2 152.0 68.3 227.1 25.2 27.3 170.7 309.3 162.4 245.1 12.7 151.9 223.8 199.3 16.9 253.8 102.0 154.5 28.1 48.8 315.3 164.8 98.9 168.2 340.6 120.0 113.1 205.1 41.7 210.4 71.6 200.6 94.7 47.0 166.8 317.7 181.6 180.9 116.9 106.9 274.3 TMEM63B "C6orf110, dJ421H19.2, DKFZp434P0531" ENSG00000137216 "Transmembrane protein 63B" Q5T3F8 6 44126914-44155519 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 87.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "OE19: 163.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029249, HPA029250, HPA029251" Uncertain Enhanced "Plasma membrane,Actin filaments" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Actin filaments" "HPA029249: AB_2672965, HPA029250: AB_2672966, HPA029251: AB_2672967" "unprognostic (8.83e-3)" "unprognostic (2.16e-2)" "unprognostic (2.42e-3)" "unprognostic (3.61e-1)" "unprognostic (2.89e-1)" "unprognostic (1.85e-1)" "unprognostic (6.97e-3)" "unprognostic (1.25e-2)" "unprognostic (1.87e-1)" "unprognostic (1.75e-1)" "unprognostic (8.60e-2)" "unprognostic (1.83e-1)" "unprognostic (1.17e-2)" "unprognostic (1.59e-1)" "unprognostic (2.67e-2)" "unprognostic (6.12e-3)" "unprognostic (3.15e-1)" 12.4 19.6 18.1 9.5 18.9 17.9 12.6 18.9 24.7 17.8 15.1 24.6 17.1 11.4 12.1 34.6 10.7 12.8 26.5 25.1 21.0 17.1 39.2 38.3 5.8 19.9 17.5 12.1 12.6 20.2 15.6 13.6 20.4 17.4 19.4 31.6 20.9 8.6 51.6 41.4 18.5 9.9 15.7 9.8 25.4 31.0 19.8 8.6 16.2 21.2 8.6 18.8 23.2 18.3 41.7 23.1 21.1 34.6 32.3 18.6 34.6 17.0 22.8 18.7 17.7 16.1 15.7 7.2 25.5 25.3 30.1 37.8 25.6 62.6 12.3 20.6 19.5 20.8 17.2 49.1 22.2 4.6 19.2 24.8 55.5 26.2 16.7 37.8 18.9 15.3 67.7 11.2 22.0 42.7 4.6 10.3 11.4 163.7 11.2 5.8 14.0 13.2 52.2 44.5 24.3 18.8 15.2 35.5 35.8 26.0 40.1 11.6 21.8 23.8 27.0 17.9 20.7 14.0 11.1 8.8 35.9 6.6 30.7 0.2 0.4 0.2 0.2 0.1 0.4 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.2 0.2 0.4 0.2 18.1 18.9 18.9 24.7 25.1 21.0 19.9 17.5 20.4 15.7 19.8 18.3 7.2 16.0 19.7 17.6 3.3 13.6 14.9 41.3 21.1 18.4 11.2 9.3 3.8 10.0 25.1 11.0 16.7 14.1 4.2 75.1 1.9 17.0 72.9 10.6 8.9 6.9 18.6 28.4 26.3 15.2 16.6 11.0 45.9 25.1 0.0 11.0 11.7 43.4 26.4 16.8 28.4 32.4 30.5 11.7 11.4 87.6 11.8 9.1 7.2 15.0 8.5 9.4 5.2 21.6 12.1 32.5 45.7 9.1 6.4 21.9 32.7 10.8 15.7 27.6 6.6 10.4 12.0 2.1 14.7 19.4 18.3 20.0 5.5 7.1 24.3 29.4 TMOD3 UTMOD ENSG00000138594 "Tropomodulin 3" Q9NYL9 15 51829628-51947295 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 397.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001849 Approved Approved "Actin filaments,Cytosol" NA NA 1200000 "Cluster 42: Non-specific - Transcription" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "Actin filaments" "HPA001849: AB_1080313" "unprognostic (6.31e-2)" "prognostic unfavorable (3.25e-4)" "unprognostic (2.39e-1)" "unprognostic (7.31e-3)" "unprognostic (1.29e-1)" "unprognostic (1.71e-1)" "unprognostic (7.53e-2)" "prognostic unfavorable (6.25e-4)" "unprognostic (3.19e-2)" "unprognostic (1.66e-1)" "prognostic unfavorable (3.38e-5)" "unprognostic (7.06e-2)" "unprognostic (7.97e-2)" "unprognostic (1.18e-1)" "unprognostic (2.15e-1)" "unprognostic (1.97e-1)" "unprognostic (5.58e-3)" 12.2 7.4 4.8 13.6 4.9 9.7 9.4 4.2 5.3 11.4 6.7 15.4 15.5 9.9 10.3 43.4 13.2 11.8 6.9 4.2 3.7 13.5 13.7 21.7 12.8 5.0 5.2 6.9 8.0 7.3 3.4 21.9 4.9 7.5 15.4 3.6 12.8 9.8 3.4 15.0 16.0 9.6 4.9 13.7 16.9 3.4 5.8 12.6 9.6 6.4 19.5 16.4 18.7 5.0 59.4 56.0 22.3 5.8 21.6 35.9 25.8 26.1 35.5 26.7 23.8 21.8 42.4 13.9 21.7 28.0 18.9 82.3 20.7 58.5 33.9 23.8 9.1 20.6 62.6 17.9 24.0 26.6 22.1 24.2 55.7 21.5 66.2 32.9 47.7 20.0 22.3 20.6 32.6 43.9 17.8 17.7 12.4 36.3 10.3 21.0 26.7 37.8 43.5 41.5 5.4 14.6 43.5 28.9 15.6 29.7 19.7 21.0 53.8 33.9 22.6 27.8 31.3 12.5 39.5 15.6 21.7 48.0 20.4 47.6 27.9 41.4 22.7 34.7 20.2 20.4 19.8 20.3 20.6 23.8 16.7 15.7 45.5 18.8 39.3 29.0 26.0 16.7 4.8 4.9 4.2 5.3 4.2 3.7 5.0 5.2 4.9 4.9 5.8 5.0 147.9 397.4 68.2 23.8 43.5 106.9 91.4 66.3 70.6 8.3 38.8 27.3 45.8 30.0 112.7 42.3 14.6 56.1 63.3 117.4 41.1 85.8 38.9 67.5 87.6 131.6 18.6 50.9 29.4 71.6 66.3 84.1 71.9 91.3 143.0 28.8 101.4 52.9 53.9 15.2 25.5 52.0 36.7 51.7 74.1 99.3 45.1 88.4 32.0 33.7 67.5 19.2 60.8 17.1 17.1 152.6 79.0 44.4 44.1 160.3 65.5 56.5 82.2 12.6 13.1 35.2 58.0 14.5 13.9 137.0 132.1 51.3 74.3 57.4 59.9 215.9 TMTC2 DKFZp762A217 ENSG00000179104 "Transmembrane O-mannosyltransferase targeting cadherins 2" Q8N394 12 82686880-83134870 "Enzymes, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 60.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 2152.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 32.0;WM-115: 80.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026954, HPA026955" Uncertain Approved "Plasma membrane,Actin filaments" No No "Cluster 37: B-cells - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "Actin filaments" "HPA026954: AB_2256025, HPA026955: AB_10602282" "unprognostic (1.56e-1)" "unprognostic (5.62e-2)" "unprognostic (9.61e-2)" "unprognostic (7.38e-2)" "unprognostic (2.60e-2)" "unprognostic (3.66e-2)" "unprognostic (1.05e-2)" "unprognostic (1.58e-1)" "unprognostic (1.25e-1)" "unprognostic (7.16e-2)" "unprognostic (1.73e-3)" "unprognostic (5.06e-2)" "prognostic favorable (2.84e-5)" "unprognostic (1.10e-1)" "unprognostic (1.60e-1)" "unprognostic (2.06e-2)" "unprognostic (8.06e-2)" 3.7 0.8 11.4 4.7 39.8 2.1 4.6 21.4 25.1 4.8 0.0 11.7 2.8 5.4 4.4 9.8 10.0 7.8 2.0 11.2 19.1 6.6 1.2 6.4 1.8 28.3 29.9 1.9 4.5 2.8 3.5 3.4 26.7 6.1 5.7 5.5 6.9 11.2 1.2 5.2 4.7 6.8 11.7 1.3 10.2 3.0 26.8 1.5 6.4 1.7 2.2 7.5 7.3 60.8 1.7 6.4 32.0 0.2 4.3 3.9 2.9 2.1 0.7 1.7 0.3 0.3 3.4 0.0 0.5 11.9 1.2 2.8 9.7 4.9 0.5 7.5 5.8 0.0 5.2 0.2 0.4 2.2 1.0 1.1 4.3 0.2 1.6 3.4 2.7 3.5 0.0 4.2 0.4 3.4 1.6 8.8 1.1 6.0 5.3 0.0 1.3 0.6 2.9 14.1 8.3 15.1 2.9 4.6 21.0 5.4 4.9 0.5 1.7 5.3 1.8 7.2 2.7 7.8 5.7 1.2 1.2 3.8 80.2 0.0 0.9 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 11.4 39.8 21.4 25.1 11.2 19.1 28.3 29.9 26.7 11.7 26.8 60.8 10.7 9.6 8.9 333.3 2.0 14.4 15.5 12.0 18.2 38.1 8.9 5.5 1.8 11.5 18.4 14.7 8.4 13.6 3.1 3.6 0.0 5.4 12.9 13.5 7.5 10.3 2.4 0.8 117.1 8.2 1.7 9.8 12.8 13.1 0.0 0.2 2.5 1.4 1.9 8.4 377.0 9.8 2.0 6.6 9.6 5.0 5.9 6.2 32.0 86.2 9.3 13.9 1.0 38.7 2152.4 9.4 3.3 1.2 7.3 11.9 2.7 2.1 17.0 1.6 6.6 0.8 2.2 0.6 2.2 16.2 11.5 4.1 2.8 1.0 5.9 14.5 TNFRSF10D "CD264, DcR2, TRAILR4, TRUNDD" ENSG00000173530 "TNF receptor superfamily member 10d" Q9UBN6 8 23135588-23164027 "Cancer-related genes, CD markers, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 114.4;Endothelial cells: 52.3;Gastric mucus-secreting cells: 83.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 99.5;LHCN-M2: 250.4;WM-115: 238.4" HPA070971 Approved "Plasma membrane,Actin filaments" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Actin filaments" "HPA070971: AB_2686330" "unprognostic (1.49e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.41e-1)" "unprognostic (8.78e-2)" "unprognostic (8.13e-2)" "unprognostic (7.49e-2)" "unprognostic (2.69e-1)" "unprognostic (7.06e-2)" "unprognostic (3.56e-2)" "unprognostic (1.66e-1)" "unprognostic (1.61e-2)" "unprognostic (1.32e-1)" "unprognostic (2.12e-2)" "unprognostic (2.70e-1)" "unprognostic (1.35e-2)" "unprognostic (6.32e-2)" "unprognostic (1.72e-1)" 10.6 2.3 4.8 5.3 4.8 9.0 4.8 4.5 6.1 3.7 6.1 6.1 4.4 4.7 3.7 2.6 5.9 7.9 6.2 4.4 4.6 12.1 17.6 10.0 3.5 4.9 4.7 7.1 3.5 1.9 2.8 2.9 5.1 4.6 7.3 0.5 2.2 2.9 1.4 2.1 6.9 7.7 5.2 5.0 5.5 3.0 6.1 1.8 3.8 1.0 4.1 3.9 3.1 5.0 15.1 12.7 16.3 9.4 12.2 47.7 0.3 78.2 29.5 5.8 7.9 24.4 12.2 0.0 16.1 47.1 0.0 5.0 13.7 68.6 50.3 0.1 12.1 4.2 7.7 21.2 52.7 2.7 5.3 60.1 75.0 20.6 14.0 71.4 99.5 0.6 0.0 0.1 250.4 0.0 0.0 8.2 13.2 44.1 0.1 3.0 0.1 3.8 19.0 6.8 0.3 0.1 8.4 0.0 0.0 36.1 0.1 9.9 59.4 0.1 0.0 4.7 0.1 0.0 0.0 0.0 63.3 4.0 238.4 2.5 2.1 0.9 0.0 0.8 0.1 1.3 1.9 0.6 2.9 0.4 5.2 2.1 1.4 0.2 1.4 0.0 0.6 1.5 4.8 4.8 4.5 6.1 4.4 4.6 4.9 4.7 5.1 5.2 6.1 5.0 114.4 0.0 9.8 0.3 7.0 5.0 4.1 11.3 14.8 0.0 6.0 12.8 3.5 1.5 10.2 1.8 0.0 0.1 1.2 6.8 0.0 5.7 0.4 6.4 5.8 52.3 1.8 0.0 0.1 2.2 0.3 19.2 83.6 9.5 7.6 1.5 16.1 8.2 2.9 0.0 0.1 5.6 6.1 6.1 9.8 0.1 0.3 13.0 8.8 19.7 3.5 0.3 0.0 0.5 0.1 12.3 3.1 0.4 6.8 4.9 6.8 2.8 6.4 0.2 0.0 11.9 14.3 0.8 2.3 4.5 2.4 0.1 5.9 2.1 6.9 3.7 TNFRSF25 "APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR" ENSG00000215788 "TNF receptor superfamily member 25" Q93038 1 6460786-6466175 "Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 44.0;pituitary gland: 29.9;skin 1: 25.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 34.1;Excitatory neurons: 37.5;T-cells: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "MAIT T-cell: 5.6;memory CD4 T-cell: 4.4;memory CD8 T-cell: 2.2;naive CD4 T-cell: 4.4;T-reg: 7.9" "Lineage enriched" "Detected in many" 7 "T-cells: 7.9" "Cell line enhanced" "Detected in many" "HDLM-2: 20.5;RPMI-8226: 25.7" "Group enriched" "Detected in some" 6 "amygdala: 1.2;cerebral cortex: 1.4;hippocampal formation: 2.0" "Not detected" "Not detected" HPA069834 Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" "Secreted - unknown location" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Actin filaments, Focal adhesion sites" Nucleoplasm "HPA069834: " "unprognostic (8.09e-3)" "unprognostic (6.91e-3)" "prognostic unfavorable (4.46e-4)" "unprognostic (1.97e-1)" "unprognostic (9.63e-3)" "prognostic favorable (3.09e-4)" "unprognostic (2.16e-1)" "unprognostic (1.46e-1)" "unprognostic (2.04e-1)" "unprognostic (2.07e-1)" "unprognostic (6.01e-2)" "unprognostic (3.98e-2)" "prognostic unfavorable (1.65e-7)" "unprognostic (1.21e-1)" "unprognostic (1.61e-1)" "unprognostic (3.44e-1)" "unprognostic (8.68e-3)" 6.4 4.2 4.0 3.2 4.0 0.8 4.0 11.1 6.1 5.2 4.9 6.1 3.0 3.0 0.6 10.3 5.7 2.2 8.7 4.8 4.3 3.3 1.2 2.4 4.3 3.7 3.6 3.1 1.5 0.9 29.9 4.4 4.4 5.2 1.4 1.2 3.3 2.3 1.1 25.3 5.0 0.5 3.3 44.0 2.0 0.9 3.7 2.0 3.2 1.2 2.7 2.5 4.6 3.5 1.8 0.4 1.1 2.0 0.0 0.6 1.3 1.5 0.6 0.3 0.0 1.7 2.8 0.0 2.5 0.0 1.3 4.2 0.6 4.7 0.0 20.5 1.5 0.6 1.7 0.1 0.7 0.0 0.1 0.0 3.2 1.5 4.1 2.7 4.0 1.1 0.0 0.0 0.0 2.2 0.0 8.0 1.4 1.4 3.4 0.6 0.3 25.7 1.3 0.7 3.4 5.3 0.0 2.5 0.1 0.6 2.0 2.9 2.5 1.3 2.1 0.0 2.0 0.0 3.5 0.0 2.4 0.0 0.0 0.0 0.0 0.0 1.0 0.2 5.6 0.0 4.4 2.2 0.5 0.0 4.4 0.7 0.0 0.8 1.0 0.0 7.9 0.9 4.0 4.0 11.1 6.1 4.8 4.3 3.7 3.6 4.4 3.3 3.7 3.5 19.0 3.2 5.0 3.9 2.5 24.6 2.3 5.6 11.4 3.1 4.2 5.5 1.1 1.5 3.3 1.8 2.1 0.7 12.8 34.1 0.0 0.2 0.2 4.1 11.2 11.5 6.7 3.0 37.5 0.4 2.0 2.3 5.6 6.9 7.0 4.8 7.9 1.1 4.0 5.0 21.6 20.3 0.0 1.2 6.6 0.3 2.8 4.0 7.2 14.0 3.0 10.2 10.3 7.5 2.1 1.4 16.0 9.4 3.2 3.7 9.8 0.6 4.8 9.1 0.0 2.6 2.6 0.4 1.2 8.6 28.6 0.1 41.4 0.7 25.0 6.8 TNNC1 TNNC ENSG00000114854 "Troponin C1, slow skeletal and cardiac type" P63316 3 52451100-52454041 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Cardiomyopathy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 36 "heart muscle: 8734.3;skeletal muscle: 21081.1;tongue: 12403.9" "Cell type enriched" "Detected in many" 10 "Cardiomyocytes: 3550.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 27.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.2" "Lineage enriched" "Detected in single" 6 "T-cells: 1.2" "Cell line enhanced" "Detected in many" "CACO-2: 68.2;CAPAN-2: 33.5;EFO-21: 65.2;HeLa: 49.1;Hep G2: 46.1;HSkMC: 67.2;U-2 OS: 97.7" "Region enriched" "Detected in all" 4 "cerebral cortex: 87.0" "Group enriched" "Detected in some" 6 "midbrain: 7.6;spinal cord: 7.1" "CAB002450, HPA044848, HPA056897" Enhanced Approved "Nucleoplasm,Actin filaments,Mitochondria" NA NA 990000 "Cluster 13: T-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 9: U-2 OS - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Actin filaments, Mitochondria" "CAB002450: AB_564152, HPA044848: AB_2679110, HPA056897: AB_2683269" "unprognostic (2.18e-2)" "unprognostic (1.70e-1)" "unprognostic (8.66e-2)" "unprognostic (3.43e-1)" "unprognostic (4.00e-2)" "unprognostic (1.88e-2)" "unprognostic (1.11e-1)" "unprognostic (1.43e-1)" "unprognostic (1.53e-1)" "unprognostic (3.92e-1)" "unprognostic (1.03e-1)" "unprognostic (1.07e-1)" "unprognostic (2.15e-2)" "unprognostic (4.95e-2)" "unprognostic (2.31e-1)" "unprognostic (4.15e-2)" "unprognostic (4.86e-1)" 8.4 10.9 0.7 0.8 0.8 0.7 19.1 2.7 1.1 7.7 7.3 4.0 1.1 2.8 41.7 387.3 2.8 3.3 8734.3 1.2 0.7 19.2 4.0 78.5 3.9 0.8 0.9 2.4 6.8 1.6 17.6 5.2 1.0 170.1 4.1 0.4 120.8 2.2 21081.1 18.9 3.3 0.8 0.8 2.8 5.7 10.6 0.8 4.3 14.4 12403.9 1.6 5.3 5.4 0.7 0.7 5.2 3.6 0.6 0.2 0.5 8.0 0.4 0.3 0.3 0.4 68.2 33.5 0.5 65.2 9.9 0.1 0.4 0.1 0.3 0.0 1.2 1.6 0.5 49.1 46.1 0.3 0.3 0.1 67.2 1.2 0.0 0.7 0.6 0.0 2.0 0.2 5.1 2.0 0.1 0.2 0.8 0.5 15.1 0.7 0.1 2.9 2.3 3.3 13.0 0.2 0.0 0.5 6.7 0.1 3.9 26.7 0.5 0.0 0.1 97.7 0.8 0.2 2.8 1.3 0.9 0.3 0.7 0.1 0.0 0.0 0.0 0.2 0.0 1.2 0.0 0.2 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.8 0.1 0.7 0.8 2.7 1.1 1.2 0.7 0.8 0.9 1.0 0.8 0.8 0.7 0.2 125.0 12.6 0.0 0.3 1.5 1.7 4.0 0.6 0.2 0.5 0.3 3550.1 5.7 7.9 3.7 2.1 59.0 0.1 1.6 27.4 11.8 0.7 66.4 6.7 39.8 330.7 0.4 0.0 13.0 5.1 52.7 0.5 98.8 0.0 0.8 0.7 0.7 4.9 0.0 0.0 1.7 2.0 0.0 1.4 5.8 22.4 2.6 5.4 0.0 0.1 1.2 0.0 0.0 0.0 6.5 0.3 177.6 0.1 0.8 0.5 1.3 2.8 0.1 0.0 241.8 36.0 2.1 1.0 0.1 0.9 31.1 2.8 1.3 2.0 6.8 TPM1 "C15orf13, CMH3" ENSG00000140416 "Tropomyosin 1" P09493 15 63042632-63071915 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 10621.0;skeletal muscle: 12678.0;tongue: 5183.6" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 13012.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 48.7" "Group enriched" "Detected in all" 4 "dendritic cells: 14.1;granulocytes: 48.7;monocytes: 19.2" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 3141.3;SuSa: 3810.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000261, HPA009066, CAB017698, HPA047089, HPA053624" Supported Approved "Actin filaments,Cytosol" NA NA 120000000 "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 12: NES - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" "Actin filaments" Cytosol "CAB017698: AB_2272017, HPA000261: AB_1080339, HPA009066: AB_1080342, HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (1.07e-1)" "unprognostic (4.20e-2)" "unprognostic (1.00e-2)" "unprognostic (6.20e-2)" "unprognostic (1.28e-1)" "unprognostic (1.45e-2)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (1.35e-2)" "unprognostic (3.27e-1)" "unprognostic (1.27e-2)" "unprognostic (1.20e-1)" "unprognostic (1.66e-3)" "unprognostic (3.38e-2)" "unprognostic (1.78e-1)" "unprognostic (5.53e-2)" "prognostic unfavorable (7.30e-4)" 372.0 103.6 49.8 232.9 53.2 21.6 348.8 52.4 53.9 577.4 59.3 2947.3 289.6 1566.9 250.5 639.0 823.8 288.0 10621.0 53.3 42.2 215.5 94.8 247.1 48.1 42.5 44.3 320.3 383.4 37.5 70.6 206.4 43.7 809.6 523.1 83.9 258.2 1545.5 12678.0 150.7 680.8 1754.9 44.8 134.3 976.5 52.3 50.0 21.1 156.8 5183.6 29.4 1511.0 425.8 42.2 554.5 357.3 418.1 20.9 143.1 89.9 1335.5 1509.1 552.8 905.9 669.2 253.9 107.6 1.7 677.7 1517.1 602.7 295.9 361.8 243.4 597.0 14.5 50.9 81.2 376.3 124.5 403.3 3.8 17.9 125.7 138.0 742.1 198.2 3141.3 243.2 14.7 8.7 20.4 695.3 286.4 25.6 7.1 496.0 129.0 61.1 9.0 146.5 15.8 1308.7 298.8 101.1 71.7 180.9 284.4 65.1 3810.3 204.8 15.3 1095.8 1178.8 572.0 181.6 1094.8 5.9 4.3 7.8 335.9 22.4 842.1 48.7 9.9 4.8 4.0 19.2 3.1 5.5 3.6 4.3 14.1 5.6 4.0 3.6 10.7 1.9 14.3 2.4 6.3 15.6 49.8 53.2 52.4 53.9 53.3 42.2 42.5 44.3 43.7 44.8 50.0 42.2 542.3 57.7 86.3 19.9 12.1 71.9 202.0 344.1 18.2 49.0 450.1 953.1 13012.4 346.0 147.0 318.2 383.7 212.1 20.6 561.3 187.9 2502.6 6.5 147.2 614.4 294.3 267.7 137.0 44.2 1671.1 3094.8 557.1 279.3 211.2 52.0 85.3 175.6 138.1 201.5 52.2 53.2 964.7 183.1 42.5 72.1 27.3 205.0 114.3 81.8 111.5 47.5 47.4 28.8 36.2 6.0 2372.3 623.4 1130.3 8.8 244.3 724.7 361.1 104.2 447.5 1038.7 484.0 1685.9 27.4 82.2 29.4 50.4 103.0 29.0 130.7 385.3 198.2 TPM3 "NEM1, TRK" ENSG00000143549 "Tropomyosin 3" P06753 1 154155304-154194648 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Disease variant, Nemaline myopathy, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 13 "skeletal muscle: 8905.8;tongue: 6106.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000261, HPA009066, HPA047089, HPA053624" Approved Approved "Actin filaments,Cytosol" NA NA 170000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 11: Alveolar cells - Smell perception" "Actin filaments" Cytosol "HPA000261: AB_1080339, HPA009066: AB_1080342, HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (1.64e-1)" "unprognostic (2.11e-2)" "unprognostic (3.01e-3)" "unprognostic (1.07e-1)" "unprognostic (2.39e-1)" "unprognostic (2.69e-3)" "prognostic unfavorable (6.73e-6)" "prognostic unfavorable (4.01e-4)" "unprognostic (2.80e-1)" "prognostic favorable (2.39e-5)" "prognostic unfavorable (3.65e-4)" "unprognostic (3.31e-2)" "prognostic unfavorable (3.12e-5)" "unprognostic (3.52e-2)" "unprognostic (1.67e-1)" "unprognostic (1.98e-2)" "unprognostic (1.00e-2)" 140.7 103.2 95.0 233.2 104.1 590.1 97.1 83.3 116.2 94.9 73.3 199.0 163.5 69.6 73.4 287.4 100.6 136.1 318.5 104.8 101.5 81.5 114.4 178.7 287.3 96.6 101.4 45.4 265.9 91.7 19.6 141.1 101.6 122.3 201.5 60.3 101.5 56.0 8905.8 103.0 167.8 111.6 94.6 208.9 152.8 64.8 93.8 203.0 88.8 6106.5 287.2 183.2 29.7 98.2 529.4 332.8 306.1 225.4 262.1 341.1 317.9 439.0 419.1 597.9 437.7 596.1 513.9 414.6 366.9 500.2 206.4 472.1 320.0 468.7 485.8 315.7 171.9 537.6 234.1 311.7 200.9 728.2 627.5 260.0 246.2 515.8 355.1 224.9 929.4 269.0 411.8 429.7 710.0 342.2 582.0 683.1 714.2 775.9 515.9 510.0 233.2 574.9 405.6 387.4 234.4 409.4 360.0 443.7 419.2 303.9 645.0 788.9 758.8 558.8 353.9 497.3 711.1 332.4 623.0 516.2 490.7 514.7 860.0 932.1 743.2 1729.3 547.2 945.6 480.1 395.2 464.0 504.4 792.6 324.5 347.2 442.6 824.3 386.4 1104.4 392.9 551.5 2029.4 95.0 104.1 83.3 116.2 104.8 101.5 96.6 101.4 101.6 94.6 93.8 98.2 346.0 621.8 343.2 17.6 318.6 149.5 227.6 169.5 127.5 84.2 135.4 88.4 85.0 125.8 275.6 97.5 31.3 127.3 475.7 494.5 105.7 292.1 72.3 353.7 191.1 395.7 141.0 189.8 65.7 347.0 331.0 170.4 245.6 474.2 531.3 119.5 200.3 110.6 559.1 304.5 50.5 291.2 93.6 355.6 504.7 182.3 46.6 648.3 152.9 31.9 704.0 54.5 466.5 12.5 30.6 530.4 363.9 29.7 218.2 204.8 220.1 179.8 230.8 62.8 19.7 155.1 128.5 38.6 67.6 223.6 143.3 101.9 422.6 119.2 302.1 324.6 TPM4 ENSG00000167460 "Tropomyosin 4" P67936 19 16067021-16103002 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 1297.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 2111.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004685, HPA047089, HPA053624" Approved Approved "Actin filaments,Cytosol" NA NA 370000000 "Cluster 44: Non-specific - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Actin filaments" Cytosol "CAB004685: AB_425723, HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (1.27e-1)" "unprognostic (1.53e-2)" "unprognostic (3.62e-3)" "unprognostic (7.38e-3)" "unprognostic (3.80e-1)" "unprognostic (2.40e-2)" "unprognostic (3.11e-2)" "unprognostic (2.75e-3)" "unprognostic (1.38e-2)" "unprognostic (3.61e-1)" "prognostic unfavorable (3.07e-4)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.26e-10)" "unprognostic (3.85e-2)" "unprognostic (2.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.78e-1)" 324.1 109.9 24.7 186.3 26.3 33.8 269.0 42.1 40.4 342.4 23.4 255.0 64.6 455.0 10.6 401.8 310.0 144.8 189.6 23.2 27.0 168.1 54.1 374.1 78.2 30.7 28.7 293.8 77.9 23.6 93.4 170.7 31.9 212.1 39.2 3.6 267.2 140.4 50.3 241.4 153.8 190.4 29.1 244.1 201.4 66.2 36.6 32.4 119.4 19.3 68.5 287.5 333.8 27.8 614.5 275.2 194.7 190.9 701.3 728.2 725.6 1082.9 470.3 356.4 357.7 325.5 473.5 31.1 724.2 492.9 383.9 331.6 72.9 386.7 141.6 503.8 138.8 305.4 270.2 232.3 357.0 52.3 728.3 715.2 94.0 327.6 331.1 353.2 427.2 115.7 46.2 217.9 360.8 290.2 152.4 233.0 227.1 461.2 380.4 201.4 413.2 143.4 87.3 387.9 75.3 315.3 670.4 155.5 298.8 90.6 5.3 60.8 1237.2 954.1 166.8 2111.0 875.3 82.4 167.3 142.5 651.4 144.5 337.0 130.8 81.4 5.9 96.0 93.9 71.4 59.6 69.0 84.3 96.6 53.0 18.6 47.2 82.1 75.2 50.4 76.8 151.0 158.4 24.7 26.3 42.1 40.4 23.2 27.0 30.7 28.7 31.9 29.1 36.6 27.8 389.4 400.6 156.6 9.4 148.6 431.1 1297.2 175.2 273.8 45.9 194.3 189.4 49.1 120.1 297.0 242.8 10.4 263.5 205.6 298.4 13.7 717.1 67.3 159.0 506.6 425.5 94.0 33.4 23.8 571.6 852.9 345.1 303.7 305.0 249.6 170.8 288.8 4.2 336.8 5.0 19.0 215.8 101.7 112.0 368.8 54.8 173.1 433.2 142.3 26.2 249.5 7.5 132.8 13.6 48.5 1017.2 258.8 547.2 310.9 900.2 61.2 29.0 133.1 11.7 335.2 170.0 516.6 29.5 10.1 328.2 343.8 568.9 192.0 222.3 162.7 1025.0 TRIM71 "LIN-41, LIN41" ENSG00000206557 "Tripartite motif containing 71" Q2Q1W2 3 32817997-32897824 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "RNA-mediated gene silencing, Ubl conjugation pathway" "Developmental protein, RNA-binding, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 4.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Extravillous trophoblasts: 15.6;Inhibitory neurons: 4.5;Oligodendrocyte precursor cells: 4.5;Spermatogonia: 13.7" "Cancer enriched" "Detected in some" 28 "testis cancer: 28.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 31.4;BEWO: 94.5;Hep G2: 63.8;NTERA-2: 84.3;SuSa: 76.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA038141, HPA038142" Uncertain Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 5: NTERA-2 - Transcription" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Actin filaments, Focal adhesion sites" "HPA038141: AB_2675857, HPA038142: AB_10697240" "unprognostic (2.93e-2)" "unprognostic (4.29e-3)" "unprognostic (1.70e-1)" "unprognostic (1.02e-2)" "unprognostic (2.58e-2)" "unprognostic (3.27e-2)" "unprognostic (2.09e-2)" "unprognostic (1.25e-1)" "unprognostic (3.16e-2)" "unprognostic (3.04e-1)" "unprognostic (1.11e-2)" "unprognostic (3.11e-1)" "unprognostic (4.36e-6)" "unprognostic (3.92e-2)" "unprognostic (9.27e-2)" "unprognostic (8.17e-2)" "unprognostic (4.65e-2)" 0.0 0.0 1.0 0.0 1.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.8 0.9 0.0 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 31.4 0.0 0.0 0.0 94.5 0.0 0.0 0.0 0.0 23.1 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 1.6 0.0 63.8 0.0 1.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.4 0.0 0.0 0.6 6.9 84.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 76.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 0.8 0.9 0.8 0.1 0.1 0.1 0.0 0.8 0.2 0.0 9.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.1 0.0 2.7 0.0 1.8 0.0 0.0 3.9 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.2 0.0 0.0 3.1 0.0 15.6 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 4.5 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 1.0 0.1 0.0 0.0 4.5 0.1 0.0 0.0 0.4 0.0 0.0 0.0 3.6 0.7 0.5 0.0 0.0 0.1 0.3 13.7 0.0 0.0 4.0 0.1 0.0 0.0 0.0 TRMT10A "MGC27034, RG9MTD2, TRM10" ENSG00000145331 "TRNA methyltransferase 10A" Q8TBZ6 4 99546709-99564039 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Diabetes mellitus, Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 99.5;Spermatogonia: 55.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047601, HPA058241" Uncertain Supported "Nucleoplasm,Nucleoli,Actin filaments,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nucleoli, Actin filaments" Cytosol "HPA047601: AB_2680099, HPA058241: AB_2683651" "unprognostic (5.24e-2)" "unprognostic (1.69e-1)" "unprognostic (1.34e-1)" "unprognostic (1.96e-3)" "unprognostic (2.10e-1)" "unprognostic (5.65e-2)" "unprognostic (1.04e-1)" "unprognostic (1.02e-1)" "unprognostic (1.59e-2)" "unprognostic (3.65e-2)" "unprognostic (1.57e-1)" "unprognostic (3.51e-1)" "unprognostic (7.49e-3)" "unprognostic (3.32e-2)" "unprognostic (2.78e-2)" "prognostic unfavorable (2.14e-4)" "unprognostic (1.68e-2)" 4.3 3.7 2.0 3.1 2.6 2.2 4.4 2.6 2.9 1.9 1.5 3.6 4.3 2.7 3.9 3.6 5.8 3.4 2.3 1.8 2.5 4.9 9.8 2.4 4.4 2.6 2.5 3.3 5.9 3.7 2.3 3.7 2.9 4.1 3.6 2.8 3.9 2.2 3.9 3.7 4.5 2.7 2.7 3.5 4.4 9.9 2.4 4.3 6.1 2.7 4.4 2.9 2.0 4.3 8.2 5.4 10.1 5.7 6.0 8.4 7.8 9.6 3.7 5.8 4.1 4.9 9.4 10.9 3.7 5.6 5.9 4.4 10.9 5.1 8.6 13.7 5.4 8.0 4.4 7.6 5.5 19.6 7.8 5.4 14.4 5.7 14.0 3.0 6.4 10.0 17.5 9.4 4.5 9.4 16.4 3.5 6.5 13.8 5.0 9.5 10.2 7.2 8.5 6.8 6.3 5.8 5.3 28.3 9.9 8.5 9.3 7.8 4.9 6.9 7.2 5.5 11.1 7.0 12.4 10.0 4.9 10.9 4.7 2.7 3.9 2.1 1.8 3.8 1.7 3.5 3.3 3.3 5.2 5.8 3.5 3.2 4.9 3.3 3.4 3.0 3.9 1.9 2.0 2.6 2.6 2.9 1.8 2.5 2.6 2.5 2.9 2.7 2.4 4.3 7.2 3.2 10.3 8.8 8.7 8.2 5.6 8.4 10.2 4.3 12.1 8.6 6.4 11.5 6.6 11.0 4.2 16.8 6.1 10.6 43.0 13.8 46.8 33.5 12.1 7.2 7.2 2.1 5.3 19.3 16.4 6.9 8.6 21.6 8.2 11.0 8.2 32.6 8.5 5.0 4.6 11.1 12.2 8.1 4.1 17.0 6.5 5.0 5.4 1.9 8.4 8.7 5.2 3.5 19.7 14.1 11.0 7.5 10.4 4.8 19.0 31.9 20.6 5.9 13.1 5.7 8.1 99.5 55.0 10.2 9.5 17.5 5.5 8.1 10.6 6.6 UQCC1 "BFZB, C20orf44, CBP3, FLJ10850, UQCC" ENSG00000101019 "Ubiquinol-cytochrome c reductase complex assembly factor 1" Q9NVA1 20 35302566-35412031 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 106.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 64.6;Inhibitory neurons: 68.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034875 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nucleoplasm, Actin filaments" "HPA034875: AB_10603226" "unprognostic (9.66e-2)" "unprognostic (3.93e-1)" "unprognostic (3.45e-1)" "unprognostic (8.72e-3)" "unprognostic (4.01e-1)" "unprognostic (1.31e-1)" "unprognostic (5.73e-2)" "unprognostic (2.75e-1)" "unprognostic (2.82e-2)" "unprognostic (7.66e-2)" "unprognostic (3.42e-2)" "unprognostic (7.01e-2)" "unprognostic (6.72e-3)" "unprognostic (3.23e-1)" "unprognostic (3.60e-1)" "unprognostic (5.27e-2)" "unprognostic (1.34e-2)" 19.4 30.0 22.0 13.8 24.3 4.6 16.5 21.9 27.7 20.1 20.9 26.0 18.9 18.6 22.9 18.8 20.6 12.6 55.3 22.4 23.0 28.6 27.1 15.8 17.9 24.1 23.5 19.8 15.9 37.2 23.9 14.9 26.6 19.7 25.8 29.5 18.7 18.4 106.8 16.3 19.3 18.5 19.9 19.7 23.0 17.6 22.9 21.2 22.3 105.7 21.9 20.1 18.0 22.8 20.2 28.6 33.5 32.2 34.1 38.4 4.8 38.5 43.3 70.7 48.1 97.7 39.4 66.6 68.5 26.1 60.7 53.5 60.0 70.0 52.6 19.0 24.2 89.2 41.3 80.3 22.7 54.2 25.6 37.6 72.3 37.9 48.8 51.2 24.6 53.5 39.9 23.9 50.0 26.8 58.6 29.2 25.4 42.0 61.5 31.4 50.0 37.9 67.6 26.2 46.4 28.7 32.9 148.9 34.0 28.1 23.9 34.6 23.5 46.2 28.8 25.9 34.6 30.1 37.2 26.5 79.7 31.1 36.8 28.6 10.2 14.2 14.8 14.3 18.3 12.3 13.7 14.7 16.0 15.7 16.7 14.7 0.3 22.3 10.2 14.4 14.2 12.6 22.0 24.3 21.9 27.7 22.4 23.0 24.1 23.5 26.6 19.9 22.9 22.8 7.0 0.0 7.8 51.6 7.0 6.4 9.3 18.1 6.8 20.7 7.8 5.8 44.0 10.0 11.8 16.5 8.4 22.9 5.3 13.9 60.7 18.2 15.1 10.5 8.5 10.5 12.0 5.2 64.6 13.1 15.7 9.2 7.7 6.9 8.2 17.5 6.1 14.2 11.6 18.5 68.9 9.1 18.3 6.6 3.9 8.6 10.5 5.8 14.2 33.7 13.2 16.7 10.3 44.2 50.3 19.1 6.6 12.0 5.0 8.4 10.9 19.4 14.8 22.8 6.6 9.6 11.9 24.6 18.2 6.2 5.3 17.4 6.2 19.7 13.2 9.6 WDR47 KIAA0893 ENSG00000085433 "WD repeat domain 47" O94967 1 108970214-109042113 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 93.6;Suprabasal keratinocytes: 104.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027287, HPA027289" Approved Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 58: Brain - Synaptic function" "Cluster 18: U-2197 - ECM organization" "Cluster 28: Keratinocytes - Keratinization" "Actin filaments" Nucleoplasm "HPA027287: AB_10599416, HPA027289: AB_10601862" "unprognostic (8.55e-2)" "unprognostic (3.36e-2)" "unprognostic (7.51e-2)" "unprognostic (2.44e-1)" "unprognostic (4.90e-1)" "prognostic favorable (9.86e-4)" "unprognostic (4.05e-3)" "unprognostic (2.83e-2)" "unprognostic (2.87e-1)" "unprognostic (3.67e-2)" "unprognostic (2.71e-2)" "unprognostic (1.93e-1)" "unprognostic (8.39e-3)" "unprognostic (7.90e-3)" "unprognostic (9.23e-2)" "unprognostic (2.73e-2)" "unprognostic (8.09e-2)" 7.8 7.1 22.6 5.5 26.6 12.2 6.3 14.1 27.3 8.8 1.5 8.0 3.7 9.3 5.7 14.4 8.5 7.3 8.1 27.7 17.9 7.6 3.5 7.0 5.6 13.4 11.0 7.5 5.9 9.2 5.3 6.5 14.6 7.3 5.3 37.0 5.8 7.0 17.0 22.9 4.5 10.2 10.9 5.7 6.0 22.7 16.7 7.7 6.2 15.3 7.5 7.5 8.9 19.5 15.6 4.7 8.8 10.9 17.0 14.8 4.7 17.4 10.7 11.4 12.7 4.6 2.3 7.0 9.0 16.7 8.4 17.1 12.5 7.6 15.0 13.1 7.0 5.8 9.9 5.3 9.7 9.2 8.3 9.2 12.4 17.9 8.5 13.8 13.7 8.1 3.5 9.5 19.4 9.3 8.9 7.2 3.7 5.0 9.1 12.5 22.3 3.9 19.0 13.3 15.3 14.0 15.2 8.1 12.5 9.4 3.7 9.3 23.5 15.1 7.0 26.7 14.5 6.1 5.4 5.5 17.6 9.0 23.0 18.0 5.4 7.1 3.3 5.7 3.1 2.4 3.1 3.5 5.8 3.4 2.8 2.5 22.0 2.7 5.9 6.3 5.5 2.6 22.6 26.6 14.1 27.3 27.7 17.9 13.4 11.0 14.6 10.9 16.7 19.5 16.5 12.8 6.5 33.3 13.8 93.6 5.1 7.7 62.0 15.3 11.1 12.6 18.9 10.0 8.0 7.3 45.9 2.4 25.1 2.7 5.9 3.5 33.2 20.5 9.3 12.1 3.0 1.7 46.2 0.9 2.1 10.7 8.2 10.4 2.5 5.6 7.1 2.0 4.4 11.8 39.1 1.0 4.1 5.5 28.4 41.4 8.4 13.9 24.9 19.7 6.3 13.2 8.2 15.1 26.5 3.9 0.9 15.1 14.9 2.4 2.4 5.5 18.9 32.3 6.6 13.5 16.5 32.2 28.9 52.1 104.4 4.9 18.9 3.3 2.1 4.1 WDR93 "C1d-87, CFAP297, FAP297" ENSG00000140527 "WD repeat domain 93" Q6P2C0 15 89690811-89743638 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 8.9;testis: 11.6" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 20.9;Early spermatids: 49.1;Endometrial ciliated cells: 28.1;Late spermatids: 42.4;Respiratory ciliated cells: 47.7;Spermatocytes: 30.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SK-MEL-30: 1.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA046196, HPA048112" Uncertain Uncertain "Actin filaments" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 49: Ciliated cells - Cilium organization" "Actin filaments" "HPA046196: AB_2679582, HPA048112: AB_2680267" "unprognostic (2.56e-3)" "unprognostic (3.21e-3)" "unprognostic (7.31e-2)" "unprognostic (1.54e-2)" "unprognostic (1.90e-2)" "unprognostic (3.01e-1)" "unprognostic (1.15e-2)" "unprognostic (2.08e-2)" "unprognostic (1.22e-2)" "unprognostic (7.40e-2)" "unprognostic (3.03e-1)" "unprognostic (1.66e-1)" "unprognostic (1.07e-1)" "unprognostic (2.40e-2)" "unprognostic (4.73e-2)" "unprognostic (9.84e-2)" "unprognostic (4.44e-2)" 0.4 0.2 0.6 0.0 0.6 0.4 0.7 1.6 0.6 0.6 3.5 0.1 0.0 0.4 4.9 0.0 8.9 0.2 1.2 0.8 1.0 1.0 0.1 1.0 0.2 2.4 2.9 0.4 0.6 0.5 0.8 0.1 1.1 0.6 0.1 2.8 0.3 0.5 0.3 0.2 0.1 0.0 1.6 0.1 0.1 11.6 0.9 0.1 1.8 0.0 0.1 0.0 0.0 1.0 0.3 0.2 0.0 0.1 0.3 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.7 0.0 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.3 0.1 0.1 0.3 0.0 0.3 0.3 0.0 0.4 0.5 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.7 0.0 0.5 0.2 0.7 0.2 1.0 0.1 0.1 0.4 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.6 0.6 1.6 0.6 0.8 1.0 2.4 2.9 1.1 1.6 0.9 1.0 0.1 3.2 0.5 2.9 0.0 0.3 0.7 1.8 0.0 2.7 0.8 0.6 0.5 0.0 4.2 9.2 20.9 0.4 0.1 0.1 3.9 0.8 49.1 28.1 0.6 0.7 0.0 0.0 2.7 0.2 0.3 0.4 0.0 0.8 0.0 0.4 0.4 0.0 0.2 3.3 2.1 0.1 0.0 0.3 0.8 42.4 1.5 0.3 1.8 0.0 0.6 0.6 0.0 0.5 1.0 0.3 1.1 0.7 0.1 0.7 0.0 2.1 47.7 14.8 0.0 0.9 0.6 30.4 5.7 0.0 0.1 0.3 0.6 2.9 0.2 0.4 WWC3 "BM042, KIAA1280" ENSG00000047644 "WWC family member 3" Q9ULE0 X 10015254-10144474 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 68.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "T-47d: 131.5" "Low region specificity" "Detected in all" HPA039814 Uncertain Approved "Actin filaments,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Actin filaments" "HPA039814: AB_10674987" "unprognostic (2.53e-1)" "unprognostic (2.17e-1)" "prognostic unfavorable (1.31e-4)" "unprognostic (9.84e-3)" "unprognostic (1.05e-1)" "unprognostic (1.80e-1)" "unprognostic (3.21e-3)" "unprognostic (1.36e-2)" "unprognostic (1.83e-2)" "unprognostic (3.58e-2)" "unprognostic (4.91e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.06e-5)" "unprognostic (9.90e-2)" "unprognostic (2.09e-1)" "unprognostic (5.03e-2)" "unprognostic (4.50e-2)" 11.2 13.8 13.7 9.6 16.9 5.5 10.9 13.0 11.8 11.2 12.2 15.2 4.0 11.3 19.3 11.3 9.7 9.7 18.6 10.3 11.4 7.3 3.4 21.7 12.6 14.1 15.1 18.1 8.5 7.8 6.5 15.7 13.4 11.3 4.8 1.9 9.3 26.7 8.5 13.5 11.6 8.3 12.4 11.6 10.8 5.4 15.1 7.1 12.2 6.4 9.6 11.0 11.3 16.6 17.2 19.1 22.7 7.5 9.4 13.2 21.6 9.6 16.5 5.7 6.2 2.5 17.5 1.8 0.2 12.8 22.0 8.8 5.3 9.9 4.7 13.0 1.9 3.9 13.1 1.7 20.1 0.0 5.8 8.5 20.4 14.1 14.8 30.0 26.7 3.2 0.3 22.4 13.7 35.2 4.2 1.1 21.4 9.0 6.7 12.5 1.1 7.5 5.5 8.7 2.4 6.4 11.7 14.9 10.2 42.0 131.5 1.4 36.0 16.4 0.5 24.4 10.8 18.2 13.3 6.3 10.0 6.3 24.7 4.0 0.8 0.2 5.8 0.7 4.9 2.0 2.8 4.3 0.4 5.0 2.5 3.0 10.7 2.6 0.7 0.6 1.4 1.8 13.7 16.9 13.0 11.8 10.3 11.4 14.1 15.1 13.4 12.4 15.1 16.6 41.0 22.4 68.4 20.2 15.4 5.6 12.9 8.2 7.4 6.1 22.9 15.9 20.5 5.7 13.0 5.5 6.2 14.3 7.1 7.9 0.0 6.2 0.7 6.3 15.4 26.9 16.1 24.8 29.0 9.5 6.3 15.3 2.6 7.5 3.8 12.7 31.8 5.6 11.6 3.3 21.1 4.2 8.2 19.4 11.8 1.4 12.8 12.2 16.0 12.2 6.8 4.1 10.3 13.0 35.7 9.5 7.4 24.8 10.2 14.8 8.1 2.5 11.5 2.0 19.7 11.9 20.2 0.7 2.5 8.8 13.1 7.9 12.0 15.8 3.6 9.4 XIRP1 "CMYA1, DKFZp451D042, Xin" ENSG00000168334 "Xin actin binding repeat containing 1" Q702N8 3 39183210-39192596 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 682.0;skeletal muscle: 383.4" "Cell type enriched" "Detected in some" 15 "Cardiomyocytes: 850.5" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.0" "Region enhanced" "Detected in some" "cerebellum: 2.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 4.4;LHCN-M2: 1.1;RH-30: 3.0" "Not detected" "Not detected" "HPA016750, HPA018458, CAB026391" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Actin filaments" Nucleoplasm "CAB026391: , HPA016750: AB_1858884, HPA018458: AB_1858885" "unprognostic (2.19e-1)" "unprognostic (6.40e-2)" "unprognostic (1.13e-1)" "unprognostic (9.75e-2)" "unprognostic (2.76e-1)" "unprognostic (2.43e-2)" "unprognostic (4.94e-2)" "unprognostic (2.66e-3)" "unprognostic (1.66e-3)" "unprognostic (1.46e-1)" "unprognostic (5.30e-2)" "unprognostic (6.26e-2)" "unprognostic (1.02e-5)" "unprognostic (2.08e-2)" "unprognostic (2.78e-2)" "unprognostic (6.86e-4)" "unprognostic (4.12e-2)" 1.1 0.3 0.0 1.2 0.0 0.0 0.2 2.0 0.3 0.0 0.1 0.7 0.0 0.2 0.0 5.6 0.0 1.0 682.0 1.1 0.1 0.1 0.1 1.7 0.0 0.6 0.2 0.1 1.2 0.0 0.5 0.7 0.2 3.4 0.0 0.0 5.1 0.0 383.4 0.5 0.5 0.4 0.2 0.6 0.3 0.0 0.1 0.5 0.2 96.4 0.0 3.5 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.3 1.1 0.1 0.6 0.2 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 850.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.2 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.4 3.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 XKR6 "C8orf21, C8orf5, C8orf7" ENSG00000171044 "XK related 6" Q5GH73 8 10896045-11201833 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 12.9" "Cell type enhanced" "Detected in many" "Astrocytes: 90.1;Excitatory neurons: 419.0;Inhibitory neurons: 339.6;Microglial cells: 106.8;Oligodendrocyte precursor cells: 290.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 4.2;U-266/84: 7.1;U-698: 3.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA024828, HPA064769" Approved "Actin filaments" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Actin filaments" "HPA024828: AB_2215165, HPA064769: AB_2732720" "unprognostic (8.63e-3)" "unprognostic (8.45e-2)" "unprognostic (1.50e-1)" "unprognostic (9.92e-6)" "unprognostic (2.09e-1)" "unprognostic (2.51e-2)" "unprognostic (1.18e-1)" "unprognostic (8.75e-3)" "unprognostic (8.65e-2)" "unprognostic (7.09e-2)" "unprognostic (2.87e-1)" "unprognostic (1.31e-1)" "unprognostic (3.78e-2)" "unprognostic (3.86e-2)" "unprognostic (2.14e-1)" "unprognostic (1.58e-1)" "unprognostic (3.29e-3)" 0.3 0.6 3.3 0.3 4.0 0.7 0.3 12.9 3.7 0.5 0.0 0.5 0.3 0.5 0.1 1.0 0.5 0.2 0.3 3.0 4.7 0.5 0.1 0.6 0.7 2.2 1.3 0.1 1.3 0.3 0.5 0.1 2.1 0.6 0.2 0.4 1.0 0.3 0.1 0.8 0.7 0.2 0.4 0.8 0.7 2.1 4.5 0.2 0.6 0.0 0.4 0.5 0.6 0.7 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.2 0.4 0.4 1.1 0.0 0.3 3.4 0.0 0.6 1.8 0.1 1.6 1.9 0.6 0.1 0.5 1.0 0.1 0.0 0.5 0.0 2.6 0.3 1.1 0.0 1.4 1.3 0.6 0.0 0.1 4.2 0.5 0.4 0.0 0.0 2.0 0.2 0.8 0.0 0.0 0.9 1.4 1.4 1.9 1.2 0.6 0.1 0.0 1.6 0.0 0.7 0.0 1.6 0.8 0.0 0.5 1.1 7.1 3.6 0.7 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.3 4.0 12.9 3.7 3.0 4.7 2.2 1.3 2.1 0.4 4.5 0.7 1.7 6.4 0.5 90.1 9.7 1.8 4.0 1.2 6.2 37.7 4.2 3.0 2.2 5.7 1.6 3.7 14.6 0.0 3.9 1.0 1.9 2.1 10.2 4.6 2.8 2.1 4.2 2.1 419.0 5.3 0.0 1.2 4.6 3.8 0.0 4.3 3.6 0.1 0.5 26.9 339.6 0.7 2.0 1.3 1.5 2.5 0.0 1.4 1.8 106.8 0.5 9.0 3.1 290.0 39.6 3.5 1.4 0.0 10.1 3.0 1.7 0.8 1.8 6.1 0.0 5.6 3.3 6.6 6.1 4.4 1.3 0.0 3.6 3.7 1.3 3.9 ZC2HC1A "C8orf70, CGI-62, FAM164A" ENSG00000104427 "Zinc finger C2HC-type containing 1A" Q96GY0 8 78666089-78719765 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 44.6" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 105.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 45.1;T-reg: 33.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 42.1;SK-BR-3: 79.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024726 Approved Approved "Actin filaments,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 31: Skin - Epidermis development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "Actin filaments" "HPA024726: AB_1846597" "unprognostic (1.12e-1)" "unprognostic (3.02e-1)" "unprognostic (5.36e-3)" "unprognostic (4.00e-2)" "unprognostic (1.13e-1)" "unprognostic (7.79e-2)" "unprognostic (1.19e-7)" "unprognostic (2.96e-1)" "unprognostic (7.25e-2)" "prognostic unfavorable (9.00e-4)" "unprognostic (2.26e-1)" "unprognostic (1.63e-2)" "unprognostic (5.41e-2)" "prognostic unfavorable (5.85e-4)" "unprognostic (2.34e-1)" "unprognostic (5.40e-2)" "unprognostic (4.05e-3)" 6.5 5.5 8.4 5.7 9.5 1.6 13.8 11.0 9.9 10.7 1.7 6.2 2.7 19.5 8.4 11.1 19.0 9.7 8.2 9.4 8.4 7.7 2.3 12.6 5.3 9.3 6.9 22.7 3.7 24.0 8.5 6.6 10.1 12.2 7.3 10.9 7.3 9.9 2.4 44.6 4.2 12.1 6.3 5.8 5.5 8.8 7.6 5.1 19.7 6.3 8.4 9.0 8.8 10.9 5.2 6.3 11.6 9.5 24.1 25.2 5.0 14.1 9.4 6.9 8.8 1.7 9.0 8.6 5.8 14.2 14.5 4.2 7.0 7.8 10.1 28.6 4.5 1.0 5.5 5.2 14.3 1.5 2.8 18.2 13.0 5.6 16.8 21.1 9.6 2.9 1.6 42.1 14.6 5.1 1.7 2.5 2.9 0.4 9.9 0.0 14.8 1.8 10.4 11.0 4.5 18.0 11.0 79.2 15.8 10.7 2.0 0.3 7.9 21.4 8.9 9.9 7.1 10.5 11.4 5.8 10.1 0.1 8.3 45.1 6.7 0.2 0.1 7.5 0.0 8.8 6.7 0.4 6.0 6.3 2.0 0.7 0.3 1.2 15.9 0.5 33.3 2.7 8.4 9.5 11.0 9.9 9.4 8.4 9.3 6.9 10.1 6.3 7.6 10.9 21.7 67.3 23.7 71.8 17.0 29.2 38.7 39.9 52.3 26.3 12.3 47.5 15.9 5.7 27.4 18.4 4.2 29.0 1.0 1.8 27.4 18.1 16.3 55.5 38.0 17.5 9.0 1.7 96.4 8.2 29.9 34.5 13.3 25.8 6.3 18.8 21.8 0.8 15.9 47.1 68.3 4.2 16.2 6.0 11.3 5.9 19.3 11.1 16.0 14.0 18.5 39.2 0.0 65.9 52.4 9.4 2.4 36.9 12.5 13.1 0.1 11.8 105.5 25.5 6.6 32.0 33.9 48.6 32.2 26.0 42.3 17.4 6.5 9.4 4.4 14.6 ZC3H13 "DKFZp434D1812, KIAA0853, Xio" ENSG00000123200 "Zinc finger CCCH-type containing 13" Q5T200 13 45954465-46052759 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 166.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039340, HPA040140, HPA047806" Uncertain Approved "Nuclear membrane,Actin filaments" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nuclear membrane, Actin filaments" "HPA039340: AB_2676454, HPA040140: AB_2676858, HPA047806: AB_2680161" "unprognostic (1.50e-1)" "unprognostic (6.28e-3)" "unprognostic (1.25e-1)" "unprognostic (2.22e-2)" "unprognostic (7.53e-2)" "unprognostic (1.24e-1)" "unprognostic (2.12e-2)" "unprognostic (3.58e-1)" "unprognostic (1.77e-1)" "unprognostic (1.71e-1)" "unprognostic (2.01e-1)" "unprognostic (1.38e-1)" "prognostic favorable (2.69e-4)" "unprognostic (1.46e-1)" "unprognostic (1.70e-1)" "unprognostic (3.45e-1)" "unprognostic (9.21e-3)" 15.4 10.1 21.9 13.4 26.9 15.0 15.9 16.9 22.0 14.8 6.7 15.0 9.3 18.5 15.3 10.7 12.0 11.4 11.7 17.4 24.9 12.7 58.6 12.6 15.9 18.4 24.2 17.7 9.4 17.7 9.1 15.5 20.4 15.6 12.3 15.7 12.5 14.3 16.0 13.8 11.7 14.6 17.9 16.4 12.0 11.4 25.2 22.5 17.5 15.8 13.1 12.9 11.0 27.3 16.6 20.9 51.1 19.9 36.0 36.6 21.4 29.9 24.5 24.1 15.9 32.3 28.9 46.4 18.8 31.9 16.6 29.0 32.1 25.0 38.4 41.4 32.5 53.3 21.0 28.2 21.2 68.5 28.3 28.2 20.4 25.5 30.0 22.9 26.6 26.5 29.1 13.8 25.6 21.6 34.8 34.7 46.2 31.7 13.4 34.9 33.1 14.2 19.9 25.4 13.4 30.4 29.6 19.0 166.2 33.6 14.7 32.0 44.7 21.5 19.3 19.6 26.3 13.8 17.2 45.5 24.5 35.9 27.8 15.3 4.6 10.5 7.4 5.7 7.4 5.4 5.2 5.8 4.6 5.1 5.1 4.6 7.7 8.8 6.9 7.9 6.3 3.9 21.9 26.9 16.9 22.0 17.4 24.9 18.4 24.2 20.4 17.9 25.2 27.3 79.1 214.7 186.1 37.5 70.9 40.7 65.6 44.2 34.7 84.6 47.3 63.5 164.0 90.1 89.0 55.2 43.8 88.3 75.8 43.6 27.4 64.5 4.2 67.0 114.7 82.7 55.6 117.6 69.4 48.6 78.6 76.2 29.6 79.8 129.3 64.1 75.7 269.2 63.5 85.8 71.2 42.4 40.7 82.5 31.4 11.8 76.7 66.0 28.4 48.7 90.2 87.1 112.3 55.3 149.5 54.7 38.7 81.6 44.0 60.9 34.4 19.5 83.9 69.2 52.6 120.2 99.4 183.6 106.0 37.7 50.6 80.3 80.8 66.9 49.7 54.5 ZFP62 "FLJ34231, ZET, ZNF755" ENSG00000196670 "ZFP62 zinc finger protein" Q8NB50 5 180847611-180861285 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048629 Approved Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 32: Non-specific - Translation" "Nucleoplasm, Actin filaments" "HPA048629: AB_2680467" "unprognostic (2.77e-2)" "unprognostic (1.77e-1)" "unprognostic (9.18e-2)" "unprognostic (1.04e-1)" "unprognostic (1.08e-1)" "unprognostic (1.98e-1)" "unprognostic (1.89e-2)" "unprognostic (9.49e-2)" "unprognostic (7.11e-3)" "unprognostic (7.29e-2)" "unprognostic (3.44e-2)" "unprognostic (1.05e-2)" "unprognostic (2.14e-1)" "unprognostic (4.34e-2)" "unprognostic (1.97e-1)" "unprognostic (4.33e-2)" "unprognostic (2.29e-3)" 7.8 7.1 8.1 12.6 8.9 4.5 13.8 12.8 10.5 12.1 7.0 14.2 13.4 13.6 15.0 13.1 15.4 9.6 9.4 7.5 10.3 11.4 6.6 9.5 18.7 8.4 7.5 19.7 11.2 13.7 8.6 9.8 7.9 12.9 17.2 18.3 11.6 11.4 14.2 15.7 13.5 10.4 5.8 13.9 16.0 8.9 7.8 24.9 23.6 14.1 20.2 10.8 11.2 11.0 13.7 10.5 21.2 28.4 14.9 13.5 26.4 13.8 10.4 11.0 15.3 24.9 33.5 34.2 21.7 6.2 12.9 20.0 10.2 24.7 16.6 58.2 19.0 19.3 30.8 8.4 10.2 17.2 11.0 10.6 20.0 11.5 20.8 17.1 10.2 19.6 16.0 18.0 15.2 31.8 25.2 9.5 14.8 12.5 24.6 22.2 22.3 19.3 9.3 24.4 28.1 19.1 20.1 15.3 15.1 15.0 23.0 15.4 14.6 17.0 14.8 8.3 14.0 18.7 23.4 16.8 14.1 22.9 13.5 6.9 2.1 2.6 2.5 2.9 4.8 4.4 3.4 3.6 2.2 4.8 6.1 5.5 1.0 3.4 3.5 2.5 3.7 2.9 8.1 8.9 12.8 10.5 7.5 10.3 8.4 7.5 7.9 5.8 7.8 11.0 10.5 9.6 11.0 5.5 12.2 7.1 8.9 10.8 11.4 8.2 9.4 11.9 11.4 8.6 7.2 0.0 2.1 6.2 6.8 12.9 15.6 9.7 24.3 9.5 5.8 8.3 10.3 12.4 9.1 16.5 6.7 6.7 7.1 7.9 8.8 16.3 9.7 5.0 6.4 1.7 9.3 17.6 8.2 5.9 4.0 28.0 17.1 5.4 5.4 6.5 7.8 11.4 9.2 9.0 10.1 14.9 7.8 11.7 11.8 8.3 15.3 9.8 6.6 13.1 13.1 7.4 8.2 30.0 14.8 7.2 4.7 5.6 9.9 11.0 15.8 8.5 ZNF185 SCELL ENSG00000147394 "Zinc finger protein 185 with LIM domain" O15231 X 152914442-152973480 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 328.7;esophagus: 326.7" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 32.2;Pancreatic endocrine cells: 72.0;Squamous epithelial cells: 69.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 51.8" "Group enriched" "Detected in many" 5 "granulocytes: 51.8;monocytes: 27.4" "Cell line enhanced" "Detected in many" "A-431: 124.4;EFO-21: 139.9;HBEC3-KT: 100.0;PC-3: 87.7;TIME: 236.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000400, HPA016438" Enhanced Supported "Plasma membrane,Actin filaments,Focal adhesion sites,Cytosol" NA NA 220000 "Cluster 18: Basophils - Vesicular transport" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "Actin filaments, Focal adhesion sites" "HPA000400: AB_1080685, HPA016438: AB_1859109" "unprognostic (1.34e-1)" "unprognostic (1.39e-1)" "unprognostic (1.84e-1)" "unprognostic (2.43e-2)" "unprognostic (9.75e-3)" "unprognostic (2.69e-1)" "unprognostic (2.49e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (7.94e-2)" "unprognostic (6.28e-2)" "prognostic unfavorable (3.30e-5)" "unprognostic (5.18e-2)" "unprognostic (8.12e-2)" "unprognostic (1.99e-1)" "unprognostic (1.37e-1)" "unprognostic (2.10e-1)" "unprognostic (1.60e-1)" 5.2 11.6 4.0 5.6 4.2 8.7 12.2 4.8 3.7 69.5 10.9 4.5 1.8 21.8 328.7 326.7 16.4 6.7 1.8 3.2 3.9 11.0 2.1 12.1 4.5 3.5 3.8 6.1 4.3 3.7 8.4 24.9 3.5 24.5 4.2 3.4 44.8 144.1 2.9 53.7 2.6 10.3 4.2 4.5 7.4 3.4 4.3 3.6 21.3 2.9 41.0 11.6 117.5 3.9 124.4 25.9 2.4 1.6 3.0 4.0 5.5 6.0 0.4 14.8 2.2 0.9 36.7 1.6 139.9 9.0 1.4 17.3 3.7 100.0 60.1 1.5 2.4 7.9 9.8 4.1 7.0 0.5 0.6 2.9 70.2 1.6 57.0 14.6 76.5 1.6 0.5 1.1 0.4 29.1 0.5 0.7 1.9 31.4 87.7 0.5 0.4 0.9 7.7 11.5 1.0 8.2 0.2 22.7 3.6 23.3 23.3 2.7 236.2 0.8 50.5 3.0 4.5 1.2 1.0 1.1 1.6 8.9 1.7 51.8 27.4 11.4 1.0 24.4 0.6 0.7 0.7 1.2 7.4 0.6 1.1 0.7 18.5 0.5 21.1 4.9 1.0 20.7 4.0 4.2 4.8 3.7 3.2 3.9 3.5 3.8 3.5 4.2 4.3 3.9 1.1 12.8 2.6 1.3 0.7 9.2 6.2 5.7 4.6 0.5 5.7 7.6 0.9 1.5 9.4 9.2 2.1 3.8 1.7 1.0 0.0 8.6 0.6 14.1 4.2 1.1 0.0 0.0 1.0 3.0 5.0 2.2 2.6 32.2 1.3 3.9 1.4 0.1 9.4 0.0 1.7 2.5 2.0 11.3 4.0 0.3 1.2 9.5 3.6 0.0 14.4 4.0 0.0 1.0 1.4 72.0 0.3 1.2 0.1 7.6 0.3 1.2 6.9 0.3 0.0 0.5 1.9 4.2 5.8 69.7 21.2 0.7 0.8 0.4 2.4 21.3 ZNF74 "Cos52, Zfp520, ZNF520" ENSG00000185252 "Zinc finger protein 74" Q16587 22 20394115-20408461 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "K-562: 47.9" HPA003354 Approved Supported "Nucleoplasm,Actin filaments" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Actin filaments" "HPA003354: AB_1080747" "unprognostic (1.40e-1)" "unprognostic (2.36e-1)" "unprognostic (2.01e-1)" "unprognostic (1.12e-1)" "unprognostic (2.76e-2)" "unprognostic (1.02e-1)" "unprognostic (8.13e-3)" "unprognostic (1.76e-2)" "unprognostic (1.30e-1)" "unprognostic (2.15e-1)" "unprognostic (1.20e-3)" "unprognostic (3.80e-2)" "unprognostic (1.10e-1)" "unprognostic (5.58e-2)" "unprognostic (3.04e-1)" "unprognostic (7.91e-2)" "unprognostic (1.44e-3)" 1.7 2.4 5.0 1.2 5.1 0.6 2.1 4.4 5.2 4.5 3.9 4.3 1.3 4.7 1.9 3.2 3.1 0.8 2.3 5.1 5.2 2.8 2.4 1.9 1.5 4.8 4.8 4.4 4.2 2.7 5.4 1.5 4.8 3.6 1.4 1.7 2.9 3.0 4.7 2.9 2.2 2.4 4.4 2.6 3.1 1.3 5.2 2.5 2.5 2.4 1.1 3.9 3.0 5.2 4.3 4.1 10.4 15.8 2.9 2.8 8.2 4.0 2.9 4.8 4.5 5.7 2.0 0.1 5.6 3.2 1.6 5.2 7.8 5.1 2.7 2.8 17.8 4.9 2.0 8.1 4.8 10.7 5.1 3.1 8.6 3.7 4.2 3.6 4.8 9.3 47.9 0.1 3.4 7.1 10.2 6.6 11.6 8.9 7.2 14.0 6.1 1.6 3.1 4.6 22.8 14.1 4.4 7.9 9.3 5.2 3.6 5.1 3.4 4.6 9.5 5.8 3.0 5.2 6.2 0.1 1.1 6.1 4.0 0.0 1.2 0.9 2.0 1.0 1.6 1.1 1.5 2.4 1.9 1.0 1.8 1.7 0.0 3.8 0.7 1.3 1.4 1.9 5.0 5.1 4.4 5.2 5.1 5.2 4.8 4.8 4.8 4.4 5.2 5.2 1.4 3.2 2.0 3.6 2.1 1.5 1.9 1.6 2.8 5.1 3.6 3.0 3.1 2.8 2.5 0.0 2.1 3.1 3.8 0.9 3.9 3.8 0.5 2.3 3.7 1.7 4.2 2.1 8.5 2.4 4.6 3.5 3.1 2.0 0.0 5.6 2.5 1.7 2.2 3.3 8.8 2.3 2.0 0.6 0.3 0.3 7.2 1.0 0.0 2.8 1.6 2.6 3.1 6.0 6.6 2.5 1.0 4.9 0.9 4.0 1.5 1.7 0.6 2.1 6.6 2.7 3.2 4.3 3.0 1.8 1.0 1.1 2.7 4.4 2.8 1.1 ZNF846 ENSG00000196605 "Zinc finger protein 846" Q147U1 19 9751993-9793180 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 242.1;Late spermatids: 91.0;Spermatocytes: 177.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA034617, HPA034618" Approved Approved "Actin filaments" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "Actin filaments" "HPA034617: AB_10603942, HPA034618: AB_2674249" "unprognostic (1.36e-1)" "unprognostic (4.70e-2)" "unprognostic (1.82e-1)" "unprognostic (2.79e-2)" "unprognostic (6.73e-2)" "prognostic favorable (5.25e-8)" "unprognostic (2.57e-1)" "unprognostic (2.62e-2)" "unprognostic (2.96e-2)" "unprognostic (2.33e-3)" "unprognostic (1.85e-2)" "unprognostic (3.05e-2)" "unprognostic (2.31e-2)" "unprognostic (1.93e-1)" "unprognostic (2.10e-1)" "unprognostic (1.32e-1)" "unprognostic (9.05e-3)" 7.9 6.6 9.3 6.2 8.9 4.5 7.0 6.5 9.1 8.5 6.6 8.2 4.2 11.1 9.6 9.2 8.5 9.7 8.2 7.2 8.0 5.0 4.6 6.9 8.1 9.5 10.2 12.9 3.9 7.3 5.5 6.3 8.5 11.8 7.2 7.4 7.1 18.7 5.4 8.0 5.3 10.6 9.2 6.4 6.6 14.0 8.9 8.0 7.3 5.7 6.3 13.1 8.9 10.3 3.8 0.8 11.6 2.8 12.8 16.4 2.6 5.8 4.0 4.1 8.2 2.1 3.1 1.5 2.3 6.9 4.8 1.4 0.8 4.5 4.5 3.4 2.5 8.6 0.3 3.1 4.6 0.8 8.9 16.9 5.9 3.1 2.4 9.4 3.4 4.6 1.5 0.0 4.4 1.5 3.1 7.2 1.7 3.1 4.8 4.5 0.9 0.4 5.2 14.6 1.8 3.5 3.1 0.3 4.4 4.0 1.9 6.0 1.8 3.3 2.4 2.8 0.5 6.5 7.3 8.3 0.4 1.1 2.9 1.1 2.1 1.3 1.7 1.7 3.5 4.2 2.6 4.3 6.9 5.2 2.0 4.2 0.8 2.2 1.2 4.5 3.3 1.6 9.3 8.9 6.5 9.1 7.2 8.0 9.5 10.2 8.5 9.2 8.9 10.3 4.4 9.6 5.4 18.3 4.7 7.9 15.0 14.5 20.5 1.7 7.3 10.0 6.8 5.7 11.9 0.0 2.1 1.6 5.5 5.4 9.8 6.5 242.1 6.4 7.7 5.1 1.2 4.8 25.8 4.9 2.1 7.8 5.1 4.5 5.1 7.8 5.7 5.4 7.5 0.0 13.7 4.9 6.1 13.9 9.1 91.0 6.8 10.2 7.2 41.2 9.2 3.2 1.0 14.6 14.6 7.0 3.9 9.1 3.7 7.3 3.1 6.1 12.5 2.4 6.6 3.7 8.2 177.1 8.6 8.0 8.8 1.2 5.2 7.8 4.1 16.4 ZSCAN22 "HKR2, ZNF50" ENSG00000182318 "Zinc finger and SCAN domain containing 22" P10073 19 58326994-58342332 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEK 293: 14.7" "Low region specificity" "Detected in all" HPA006471 Uncertain Uncertain "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 15: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Cytosol" "Actin filaments" "HPA006471: AB_2221026" "unprognostic (5.55e-3)" "unprognostic (2.24e-1)" "unprognostic (6.56e-2)" "unprognostic (1.13e-1)" "unprognostic (1.93e-1)" "unprognostic (3.82e-2)" "unprognostic (2.47e-3)" "unprognostic (1.52e-1)" "unprognostic (2.91e-1)" "unprognostic (1.15e-1)" "unprognostic (2.15e-3)" "unprognostic (5.00e-2)" "unprognostic (7.59e-2)" "unprognostic (2.59e-2)" "unprognostic (1.74e-1)" "unprognostic (5.22e-3)" "unprognostic (1.07e-1)" 1.2 1.5 1.4 1.3 1.7 0.7 1.1 2.9 1.6 1.7 1.0 1.5 1.2 1.5 0.8 1.8 1.3 0.7 1.2 1.3 1.4 1.3 2.4 1.1 1.2 1.4 1.2 1.5 1.4 1.6 2.6 1.2 1.4 1.4 0.9 0.8 1.2 1.0 1.1 2.3 1.3 1.2 0.8 1.4 1.4 1.2 1.2 1.1 1.3 1.0 1.4 1.5 1.5 2.8 2.4 4.2 2.3 3.5 2.6 1.6 2.4 2.0 1.0 1.2 1.1 2.3 1.7 1.9 1.3 1.6 1.5 1.8 3.3 2.2 1.3 3.0 14.7 4.1 4.2 2.1 2.1 3.3 4.2 1.8 2.2 2.6 2.7 2.2 1.8 1.9 4.1 3.6 2.1 1.9 1.6 1.5 2.0 3.0 4.8 2.2 3.6 3.3 1.2 3.1 3.6 2.6 3.0 4.0 2.0 1.8 1.9 2.3 1.8 6.5 1.9 1.6 3.5 3.6 5.3 1.4 2.6 2.2 2.3 0.0 0.8 1.0 2.0 0.7 1.3 0.8 1.1 1.6 1.1 1.0 0.9 1.0 0.2 1.2 0.9 0.5 0.9 1.0 1.4 1.7 2.9 1.6 1.3 1.4 1.4 1.2 1.4 0.8 1.2 2.8 1.1 0.0 4.1 1.6 1.5 1.8 0.6 1.0 0.0 0.7 1.3 0.9 0.6 1.5 1.6 1.8 0.0 0.9 0.8 0.4 1.9 0.9 0.3 1.1 1.2 0.9 0.0 1.7 2.1 0.6 0.9 1.1 1.1 1.6 0.0 1.1 0.0 1.3 0.5 1.7 2.1 0.5 0.0 0.8 0.8 0.0 2.1 2.3 1.8 0.0 1.3 0.5 0.0 1.0 2.2 1.1 1.6 0.4 1.1 0.9 0.8 0.6 1.1 0.7 0.0 1.7 0.8 4.3 1.9 1.1 3.7 0.7 1.2 0.9 1.0 0.4 ZSCAN29 "FLJ35867, Zfp690, ZNF690" ENSG00000140265 "Zinc finger and SCAN domain containing 29" Q8IWY8 15 43358172-43371025 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 81.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007241, HPA011109" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 16: U-266 - Nucleosome" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane, Actin filaments" "HPA007241: AB_10600420, HPA011109: AB_10611525" "unprognostic (3.90e-2)" "unprognostic (2.70e-1)" "unprognostic (1.15e-1)" "unprognostic (4.06e-2)" "unprognostic (2.21e-2)" "unprognostic (2.02e-2)" "unprognostic (1.57e-1)" "unprognostic (5.25e-1)" "unprognostic (2.12e-2)" "unprognostic (4.77e-3)" "unprognostic (1.64e-1)" "unprognostic (1.44e-3)" "unprognostic (9.61e-2)" "unprognostic (1.30e-1)" "unprognostic (1.31e-1)" "unprognostic (8.33e-2)" "unprognostic (3.43e-2)" 6.3 5.6 7.9 8.6 10.1 5.6 6.8 8.1 7.4 7.2 8.1 7.6 8.8 8.9 5.2 7.2 6.4 6.0 5.5 6.6 7.4 5.7 6.9 6.9 10.7 9.3 9.7 7.4 11.4 7.7 5.5 8.1 8.9 6.8 7.6 13.6 8.5 6.5 9.7 5.8 9.9 6.4 7.7 9.0 8.8 17.3 8.5 10.7 7.2 8.5 10.4 6.6 6.0 10.3 11.7 12.5 28.9 17.9 10.0 10.5 15.6 9.0 13.9 15.6 16.2 19.7 8.1 11.4 14.7 11.1 12.6 33.7 21.5 11.0 13.9 29.6 11.8 25.1 20.5 15.5 11.1 17.3 21.2 9.3 19.0 10.6 14.9 11.0 8.0 17.3 23.7 13.5 12.7 7.4 16.7 14.2 14.5 17.1 9.6 25.7 16.1 14.0 9.1 13.9 20.6 22.2 13.9 22.5 10.4 14.5 15.8 26.6 9.1 18.3 14.4 14.0 16.4 25.8 38.4 21.6 10.7 16.9 14.1 0.4 0.3 3.1 0.4 0.4 0.3 0.8 0.4 0.3 0.4 0.5 0.2 0.6 0.7 1.0 0.3 0.3 0.8 0.3 7.9 10.1 8.1 7.4 6.6 7.4 9.3 9.7 8.9 7.7 8.5 10.3 3.5 6.4 7.9 6.8 5.8 3.6 2.6 3.7 4.6 10.8 4.8 4.8 7.8 4.3 7.8 7.3 27.1 5.1 7.1 11.0 0.0 5.4 81.7 5.0 8.2 4.9 6.1 1.3 6.4 7.1 4.4 5.8 9.7 7.8 0.0 6.5 3.9 7.2 5.8 13.5 5.2 8.1 4.1 10.6 3.7 20.7 6.8 4.8 5.4 9.4 6.7 5.5 10.3 10.1 10.2 8.7 5.0 6.0 3.3 3.9 7.7 2.6 5.2 18.0 0.0 4.9 3.8 12.0 6.7 4.4 3.1 3.8 4.2 2.8 7.0 2.4 ZYX ENSG00000159840 Zyxin Q15942 7 143381295-143391111 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 596.6" "Cell type enhanced" "Detected in many" "Macrophages: 207.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 163.3" "Group enriched" "Detected in all" 4 "dendritic cells: 58.4;granulocytes: 163.3;monocytes: 83.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004835, CAB009321, HPA073497, CAB075747" Enhanced Supported "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 180000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "Focal adhesion sites" "Plasma membrane, Actin filaments" "CAB009321: AB_2221290, CAB075747: AB_2665753, HPA004835: AB_1080771, HPA073497: AB_2686611" "unprognostic (1.96e-2)" "unprognostic (5.35e-2)" "unprognostic (2.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.44e-2)" "unprognostic (1.18e-1)" "unprognostic (2.21e-3)" "unprognostic (1.66e-3)" "unprognostic (2.60e-1)" "unprognostic (4.22e-1)" "unprognostic (1.98e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (7.92e-5)" "unprognostic (1.39e-1)" "unprognostic (8.12e-2)" "unprognostic (1.95e-1)" "unprognostic (6.72e-2)" 211.5 75.4 21.6 82.5 24.3 106.3 191.0 24.4 33.5 275.7 24.8 382.6 28.1 596.6 16.5 136.7 294.9 57.0 152.0 21.9 21.9 99.4 89.9 316.8 53.9 27.5 24.7 168.7 78.5 84.3 52.4 38.4 27.5 171.9 20.2 5.2 108.1 75.3 113.3 130.7 148.7 127.7 23.8 213.6 154.0 98.9 28.8 27.6 89.0 19.1 31.1 301.6 185.9 26.8 73.9 39.3 50.6 70.5 93.9 208.2 63.4 152.1 158.9 146.5 122.7 135.4 42.6 4.6 57.5 168.5 84.1 55.8 31.7 138.0 67.8 81.6 18.7 105.9 45.7 46.9 163.8 86.4 162.6 222.9 60.5 160.1 54.0 90.5 187.9 9.1 28.0 42.8 159.6 73.4 1.3 165.9 110.0 25.4 273.1 16.3 28.0 6.4 112.2 34.6 2.8 39.5 112.3 99.2 57.0 45.9 12.1 80.5 343.7 176.5 74.1 187.9 152.4 15.6 20.4 11.7 154.6 87.4 119.8 18.9 70.8 48.2 20.2 70.4 16.2 3.1 19.4 23.3 58.4 2.0 11.7 13.8 163.3 14.7 83.6 14.5 19.1 44.1 21.6 24.3 24.4 33.5 21.9 21.9 27.5 24.7 27.5 23.8 28.8 26.8 51.6 6.4 6.4 8.1 26.7 33.8 174.0 78.4 26.7 3.7 40.2 85.3 11.6 25.8 45.4 35.0 0.0 40.6 51.7 40.1 7.9 100.3 1.5 23.4 172.6 58.2 38.2 19.3 36.9 94.1 95.8 66.6 44.9 42.0 36.8 13.7 55.3 32.0 164.6 0.0 18.3 26.7 24.4 195.7 95.1 6.8 28.6 207.1 14.2 7.5 171.9 15.1 40.2 7.5 5.2 169.8 48.2 55.3 20.3 61.3 19.8 19.6 9.9 3.0 85.5 48.7 103.9 7.3 9.9 46.3 20.2 28.0 91.9 8.8 28.6 106.4