Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AASS "LKRSDH, LORSDH" ENSG00000008311 "Aminoadipate-semialdehyde synthase" Q9UDR5 7 122064583-122144308 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 44.3" "Cell type enhanced" "Detected in many" "Astrocytes: 145.9;Hepatocytes: 113.9;Oligodendrocyte precursor cells: 106.1;Oligodendrocytes: 132.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 41.5;NTERA-2: 55.3;SuSa: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020637, HPA020728, HPA020734" Enhanced Approved Nucleoplasm,Vesicles,Mitochondria Yes No 19000 "Cluster 15: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria "Nucleoplasm, Vesicles" "HPA020637: AB_1844415, HPA020728: AB_1844416, HPA020734: AB_1844417" "unprognostic (4.84e-2)" "unprognostic (2.29e-1)" "unprognostic (7.91e-4)" "unprognostic (6.08e-2)" "unprognostic (1.49e-2)" "unprognostic (8.00e-2)" "prognostic favorable (9.81e-4)" "unprognostic (4.48e-3)" "unprognostic (2.38e-1)" "unprognostic (1.47e-1)" "unprognostic (1.98e-1)" "unprognostic (1.99e-1)" "unprognostic (7.76e-3)" "unprognostic (8.56e-3)" "unprognostic (1.55e-1)" "unprognostic (6.50e-2)" "unprognostic (2.67e-1)" 9.7 5.9 10.0 1.8 12.2 0.2 8.4 10.3 14.4 8.2 15.5 5.2 0.9 9.5 7.5 3.2 11.7 2.1 9.2 9.4 10.6 13.9 44.3 6.3 1.4 11.6 11.0 25.2 4.8 7.1 3.5 3.2 11.4 5.4 1.4 3.7 3.5 4.8 8.6 2.8 3.6 4.4 10.1 2.9 5.5 2.2 11.0 1.5 4.7 6.2 1.4 6.9 6.2 11.8 0.1 0.0 21.9 41.5 27.3 13.5 9.4 5.4 8.0 7.3 9.1 12.6 0.1 0.0 0.2 6.6 8.3 4.1 33.5 16.8 9.6 0.0 12.2 9.4 4.3 12.5 22.0 0.0 2.9 12.2 0.5 9.2 7.1 18.9 19.8 12.1 2.7 15.5 5.1 0.1 0.9 0.0 55.3 0.1 1.7 11.8 16.3 0.3 5.3 2.4 2.7 0.7 1.5 0.0 5.3 37.8 0.5 0.0 8.1 13.6 3.4 7.0 8.3 3.5 3.0 0.0 4.9 0.8 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10.0 12.2 10.3 14.4 9.4 10.6 11.6 11.0 11.4 10.1 11.0 11.8 16.0 9.6 37.8 145.9 2.1 6.2 9.0 2.8 14.8 7.0 8.7 6.3 9.7 14.3 5.6 14.7 16.7 11.6 1.5 0.6 0.0 2.7 12.2 4.1 24.0 11.7 3.0 5.2 5.0 1.8 3.3 14.4 5.6 7.7 3.8 18.1 24.7 113.9 1.5 11.8 4.4 2.6 2.0 2.2 2.5 7.4 19.0 1.4 12.4 35.6 0.0 8.9 0.0 106.1 132.5 2.3 2.5 24.5 1.6 4.7 5.4 8.6 0.9 3.3 19.7 38.9 15.8 12.4 2.4 7.8 4.7 5.1 2.1 8.0 1.9 4.8 ABL1 "ABL, c-ABL, JTK7, p150" ENSG00000097007 "ABL proto-oncogene 1, non-receptor tyrosine kinase" P00519 9 130713016-130887675 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Autophagy, Cell adhesion, DNA damage, DNA repair, Endocytosis" "DNA-binding, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 71.2;Oligodendrocytes: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002686, HPA027251, HPA027280, HPA028409" Supported Enhanced "Nucleoplasm,Nuclear bodies" Yes No "Cluster 37: B-cells - Transcription" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies" "CAB002686: , HPA027251: AB_1844453, HPA027280: AB_1844454, HPA028409: AB_10601011" "unprognostic (4.82e-2)" "unprognostic (3.99e-2)" "unprognostic (5.55e-2)" "unprognostic (4.72e-2)" "unprognostic (1.16e-1)" "unprognostic (1.46e-1)" "unprognostic (3.75e-3)" "unprognostic (1.89e-3)" "unprognostic (2.34e-1)" "unprognostic (2.54e-2)" "unprognostic (1.09e-2)" "unprognostic (1.48e-1)" "unprognostic (3.96e-3)" "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" 50.9 30.7 27.4 25.3 38.9 23.4 45.8 33.6 31.4 60.5 40.4 96.4 23.1 63.0 11.6 33.8 55.6 35.7 36.1 26.6 28.3 23.1 17.5 37.3 16.3 39.3 38.5 56.0 24.9 32.5 34.9 26.5 35.8 43.5 26.7 14.2 32.4 33.6 29.4 36.3 45.2 41.2 31.3 23.3 51.6 20.1 34.9 22.4 46.7 30.8 15.4 79.3 42.7 41.3 22.5 48.3 53.6 62.9 76.5 93.3 18.8 38.8 60.4 44.8 38.1 36.4 28.3 32.3 22.3 52.0 47.6 42.5 23.5 36.0 30.7 20.6 16.3 23.7 84.1 33.4 51.8 36.5 32.3 68.8 37.2 80.6 50.0 64.1 61.0 47.9 135.8 26.5 54.9 42.0 49.2 30.5 57.9 34.3 33.8 55.9 67.9 35.9 45.0 25.7 47.9 60.1 66.1 23.5 29.2 31.0 46.2 33.1 71.1 170.7 44.1 66.3 62.6 8.4 20.3 47.9 72.1 27.6 55.1 0.0 0.7 0.3 0.6 0.4 0.8 1.3 0.6 0.6 0.7 0.4 0.6 0.5 0.0 0.8 1.9 1.0 0.3 0.6 27.4 38.9 33.6 31.4 26.6 28.3 39.3 38.5 35.8 31.3 34.9 41.3 16.2 9.6 13.6 54.9 4.7 9.2 7.3 9.8 5.2 8.2 11.6 10.2 6.2 7.2 7.2 14.7 12.5 13.6 12.1 21.2 1.9 14.4 5.9 8.6 29.7 18.1 22.1 4.6 52.5 11.1 4.3 36.7 5.6 12.4 2.5 22.1 20.3 15.9 16.6 10.1 63.7 17.5 6.1 16.4 11.7 8.8 28.0 10.2 5.4 71.2 6.6 19.2 6.2 66.9 116.0 17.9 18.3 25.6 5.6 8.6 11.6 10.3 7.8 9.1 19.7 29.5 19.8 16.9 16.5 6.6 6.8 15.2 7.9 20.1 21.4 7.2 ABRAXAS2 "ABRO1, Em:AC068896.4, FAM175B, KIAA0157" ENSG00000165660 "Abraxas 2, BRISC complex subunit" Q15018 10 124801819-124836667 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 25.6;Collecting duct cells: 23.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037591, HPA037592, HPA074089" Approved Supported Cytosol Yes No "Cluster 41: Basophils - Cellular respiration" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA037591: AB_10671877, HPA037592: AB_2675566, HPA074089: AB_2686659" "unprognostic (2.78e-1)" "unprognostic (1.63e-1)" "unprognostic (1.66e-1)" "unprognostic (6.47e-2)" "unprognostic (1.08e-1)" "unprognostic (3.51e-2)" "unprognostic (5.52e-2)" "unprognostic (2.19e-1)" "unprognostic (2.99e-1)" "unprognostic (6.81e-2)" "unprognostic (3.72e-2)" "unprognostic (2.09e-2)" "unprognostic (1.80e-3)" "unprognostic (3.09e-2)" "unprognostic (1.58e-1)" "unprognostic (1.42e-1)" "unprognostic (1.66e-1)" 9.1 10.5 8.0 10.3 8.3 12.3 12.2 8.0 9.9 8.8 6.6 9.9 10.2 9.4 9.3 9.8 9.0 8.2 10.0 8.4 8.6 12.3 13.7 9.3 12.5 7.8 8.4 10.4 8.3 12.7 3.9 10.3 8.5 9.5 10.3 5.3 8.5 8.8 19.0 11.6 10.8 10.5 7.7 10.0 9.5 6.7 8.2 12.9 12.7 16.2 13.3 9.7 6.8 7.9 22.2 14.9 15.7 21.6 19.9 19.6 13.5 22.4 35.1 26.2 24.1 12.1 20.9 24.7 18.6 24.4 14.2 24.4 25.0 21.0 27.5 21.6 17.2 18.8 11.8 15.0 25.4 32.6 18.9 21.6 25.1 25.8 46.4 28.3 20.1 21.7 20.0 16.6 21.6 14.5 25.1 29.1 13.5 20.0 13.8 20.0 16.6 15.1 19.5 11.1 10.8 19.8 17.9 17.0 24.4 15.8 14.0 22.2 17.4 14.0 11.2 16.5 27.1 17.2 17.1 23.6 18.3 15.9 10.1 22.8 10.5 9.8 7.6 14.5 10.5 10.5 8.8 10.6 12.9 11.6 9.3 10.3 4.1 7.7 11.8 8.7 11.4 7.0 8.0 8.3 8.0 9.9 8.4 8.6 7.8 8.4 8.5 7.7 8.2 7.9 15.1 25.6 14.3 0.0 3.5 0.0 0.0 0.0 0.0 0.0 9.4 10.3 0.0 0.0 6.2 23.9 0.0 16.9 7.0 0.0 17.6 13.7 0.0 11.1 15.6 6.3 0.0 0.0 0.0 12.5 13.0 5.5 0.0 12.3 12.6 12.4 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 20.7 0.0 0.0 0.0 0.0 10.2 0.0 0.0 1.6 0.0 0.0 18.6 12.4 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 16.0 4.3 13.5 0.0 0.0 AC008397.2 ENSG00000285188 "Novel protein" 19 18207961-18255419 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "stomach 1: 3.6" "Cell type enhanced" "Detected in some" "Adipocytes: 2.0;Alveolar cells type 1: 9.6;Alveolar cells type 2: 10.6;Breast glandular cells: 2.2;Breast myoepithelial cells: 4.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-87 MG: 1.2" "HPA048975, HPA054218" Uncertain Approved "Midbody ring,Centrosome,Cytosol" Yes NA "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 11: Alveolar cells - Smell perception" "Centrosome, Cytosol" "Midbody ring" "HPA048975: AB_2680581, HPA054218: " 0.1 0.0 1.8 0.1 2.3 0.0 0.0 1.2 2.3 0.3 1.2 1.2 0.8 0.7 1.9 0.1 0.7 0.3 0.5 2.1 1.5 0.4 0.0 1.2 0.0 1.3 1.5 0.2 0.4 0.0 0.6 1.4 0.2 1.0 0.0 0.0 0.7 2.4 0.0 0.5 0.5 1.3 0.4 3.6 0.3 1.6 0.0 0.0 2.6 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.3 1.2 2.3 2.1 1.5 1.3 1.5 1.4 1.3 1.6 1.6 2.0 9.6 10.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.2 4.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.5 0.0 0.0 0.0 0.4 0.0 0.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 AC013489.1 ENSG00000173867 "Novel transcript" 15 88459501-88546585 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Group enriched" "Detected in some" 5 "granulocytes: 1.3;Respiratory ciliated cells: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in some" HPA048873 Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes NA "Cluster 32: T-cells - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" Microtubules "Nucleoplasm, Cytokinetic bridge" "HPA048873: AB_2680541" "unprognostic (3.32e-2)" "unprognostic (9.46e-3)" "unprognostic (1.47e-1)" "unprognostic (1.47e-1)" "unprognostic (2.84e-2)" "unprognostic (6.56e-3)" "unprognostic (4.03e-1)" "unprognostic (1.88e-2)" "unprognostic (1.01e-1)" "unprognostic (1.02e-2)" "unprognostic (2.29e-2)" "unprognostic (1.10e-2)" "unprognostic (2.62e-3)" "unprognostic (1.79e-1)" "unprognostic (4.47e-1)" "unprognostic (2.21e-1)" "unprognostic (1.66e-2)" 0.4 0.4 0.6 0.2 0.6 0.4 1.1 0.7 0.7 0.4 0.9 0.5 0.3 2.2 1.0 0.3 1.0 0.5 0.8 0.5 0.9 0.7 0.8 0.5 0.4 0.6 0.6 2.2 1.0 0.7 0.5 0.7 0.6 0.6 1.3 0.4 0.7 1.4 0.3 0.4 0.9 0.6 0.7 0.4 0.4 0.7 0.5 0.7 1.2 0.5 0.3 0.8 0.3 0.6 0.5 0.8 1.2 0.6 0.6 1.0 0.7 1.0 0.7 0.6 1.1 0.9 0.7 1.2 0.7 0.6 2.1 0.6 0.9 0.3 1.0 1.0 0.5 0.8 0.4 0.8 0.7 1.0 1.1 0.7 0.8 0.4 0.5 1.2 1.0 0.9 0.1 0.4 1.0 0.5 0.6 0.7 0.2 0.4 0.7 1.2 0.6 0.8 0.6 0.4 0.9 0.4 1.4 1.0 0.7 1.5 0.8 0.7 0.5 0.9 0.9 0.5 0.9 0.6 0.9 0.7 0.5 0.0 0.5 0.3 0.7 0.9 0.8 0.9 0.9 0.8 0.8 0.7 1.0 1.1 0.0 0.9 0.6 0.6 0.8 0.9 0.6 0.6 0.7 0.7 0.5 0.9 0.6 0.6 0.7 0.6 0.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC026464.4 ENSG00000260914 "Novel protein" 16 69299682-69322700 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 156.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA060092 Approved Midbody Yes NA "Cluster 26: Non-specific - Mitochondria" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 11: Alveolar cells - Smell perception" Midbody "HPA060092: AB_2684203" "unprognostic (2.95e-1)" "unprognostic (4.21e-1)" "unprognostic (7.34e-2)" "unprognostic (8.50e-2)" "unprognostic (1.02e-1)" "unprognostic (2.74e-1)" "unprognostic (3.50e-1)" "unprognostic (4.08e-2)" "unprognostic (6.51e-4)" "unprognostic (1.69e-1)" "unprognostic (2.76e-1)" "unprognostic (5.11e-2)" 44.1 30.4 24.3 29.1 27.0 28.6 31.8 26.0 37.3 28.4 14.9 36.4 30.5 32.6 12.3 41.7 29.4 22.0 43.2 28.4 27.4 30.3 20.7 28.8 28.0 28.5 25.1 33.7 47.2 47.6 16.1 29.4 29.1 27.7 26.4 35.4 36.1 26.6 156.6 34.6 35.1 31.7 25.2 29.9 31.7 18.7 27.4 26.2 30.3 97.2 30.0 32.2 28.3 30.1 64.9 56.5 65.5 62.3 48.9 51.3 36.9 80.1 53.7 83.6 54.6 72.3 35.1 61.6 81.7 64.5 42.9 49.7 62.2 54.6 52.9 38.2 30.0 48.9 30.1 37.3 61.5 62.3 49.8 43.7 73.8 69.2 75.7 47.9 70.0 52.4 63.2 29.6 68.7 84.5 62.1 30.8 53.1 42.7 27.0 94.3 37.4 82.1 38.7 41.2 67.7 38.1 107.8 35.6 47.7 39.9 50.7 43.0 74.0 77.7 55.5 67.8 61.3 101.4 78.6 147.0 78.7 23.3 94.8 16.1 25.4 36.1 31.0 20.7 28.4 23.0 27.4 36.9 26.8 20.2 27.7 27.4 17.1 22.5 28.3 18.5 28.5 33.7 24.3 27.0 26.0 37.3 28.4 27.4 28.5 25.1 29.1 25.2 27.4 30.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC087721.2 ENSG00000285920 "Novel protein" 15 41284007-41380996 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Alveolar cells type 1: 6.4;Alveolar cells type 2: 5.3;Club cells: 5.6;granulocytes: 3.8;Respiratory ciliated cells: 2.9" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "HPA042904, HPA074847" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" Yes Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Nucleoli, Nucleoli fibrillar center" "HPA042904: AB_2678220, HPA074847: AB_2732269" 0.8 1.5 0.3 1.8 0.2 2.9 1.3 2.1 1.0 1.0 0.1 1.8 1.7 0.9 0.3 1.6 0.7 1.1 0.8 0.1 0.3 1.1 1.7 1.0 2.4 0.4 0.6 1.5 0.6 0.9 1.3 0.5 0.7 1.9 1.8 0.6 1.1 3.1 1.0 1.4 1.1 0.2 1.6 1.2 2.9 0.6 2.6 0.7 1.9 2.5 1.5 0.4 3.7 1.2 6.6 5.5 2.5 3.7 3.4 3.8 2.9 4.8 4.7 2.0 4.1 2.8 4.0 2.2 4.4 8.7 10.1 5.3 4.1 7.2 3.6 9.4 3.8 3.6 2.0 14.2 8.2 2.1 3.3 3.3 8.8 1.9 4.7 10.6 8.7 11.0 4.3 1.8 5.5 4.5 6.9 9.2 5.5 7.6 5.0 4.3 4.6 4.0 6.6 6.0 6.6 3.9 2.6 7.0 6.6 8.5 4.3 2.8 5.5 3.2 5.8 5.6 10.7 9.4 2.4 8.7 5.6 0.1 0.4 1.0 0.2 0.4 0.3 0.4 0.5 0.4 0.6 0.3 0.2 0.2 0.1 0.3 0.5 0.9 0.9 0.5 0.3 0.2 2.1 1.0 0.1 0.3 0.4 0.6 0.5 0.2 0.6 0.4 0.0 6.4 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 AC092143.1 ENSG00000198211 "Novel protein (MC1R-TUBB3 readthrough)" 16 89919165-89936092 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "testis: 6.6" "Cell type enriched" "Detected in single" 15 "Fibroblasts: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "SK-MEL-30: 10.7" "CAB011512, HPA043640, HPA046280" Uncertain Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 78: Testis - Spermatogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 11: Alveolar cells - Smell perception" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB011512: AB_444319, HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (2.90e-4)" "unprognostic (6.87e-2)" 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 6.6 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.7 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.5 0.1 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACBD4 FLJ13322 ENSG00000181513 "Acyl-CoA binding domain containing 4" Q8NC06 17 45132600-45144181 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 93.0" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 56.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051772 Approved Approved Nucleoplasm,Vesicles Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 85: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Vesicles" "HPA051772: AB_2681603" "unprognostic (1.57e-2)" "unprognostic (1.45e-1)" "unprognostic (2.59e-2)" "unprognostic (1.54e-1)" "unprognostic (5.33e-3)" "unprognostic (1.60e-2)" "prognostic favorable (4.76e-4)" "unprognostic (2.27e-2)" "unprognostic (9.06e-2)" "unprognostic (4.86e-2)" "prognostic favorable (4.64e-4)" "unprognostic (8.24e-2)" "unprognostic (2.04e-3)" "unprognostic (1.97e-1)" "unprognostic (2.12e-1)" "unprognostic (1.27e-1)" "prognostic favorable (6.53e-4)" 11.1 17.2 14.4 6.3 14.1 4.1 12.9 13.9 16.6 19.1 13.1 21.2 29.9 14.4 4.0 7.1 22.3 6.6 11.8 13.4 13.9 24.6 93.0 9.6 9.9 14.2 14.0 19.3 20.0 14.5 15.8 4.3 13.4 21.6 5.7 10.3 14.1 12.2 6.8 9.0 25.9 5.7 14.5 16.2 14.7 4.2 14.2 5.4 21.1 5.1 6.4 15.7 13.6 13.2 7.9 15.4 1.9 4.2 3.5 6.4 5.1 2.9 6.1 4.7 9.2 6.0 10.8 8.4 7.4 4.3 2.8 7.3 2.6 4.8 1.9 12.2 5.9 4.2 11.3 12.0 7.5 1.6 11.1 6.4 4.6 1.7 2.4 16.1 4.6 7.7 2.7 13.1 2.3 5.3 6.0 2.1 0.3 8.3 4.2 4.8 0.5 18.8 11.8 5.1 3.1 1.4 2.1 3.1 8.9 1.0 20.1 3.0 1.7 1.2 3.6 1.8 1.8 20.4 5.9 2.6 6.8 2.1 2.0 4.4 2.3 3.5 2.9 2.6 3.2 3.7 3.4 3.2 2.0 5.0 3.7 4.3 0.5 4.0 1.7 1.3 4.3 3.2 14.4 14.1 13.9 16.6 13.4 13.9 14.2 14.0 13.4 14.5 14.2 13.2 5.7 3.2 3.0 12.4 7.8 1.9 5.9 3.9 2.8 16.6 7.4 6.9 9.7 14.3 2.6 3.7 22.9 6.3 5.9 9.6 7.9 7.3 1.4 2.0 2.7 5.3 6.0 2.1 7.2 7.1 1.3 7.3 4.6 3.6 8.2 7.4 5.0 21.8 5.3 11.8 8.5 7.8 6.1 1.9 2.6 5.0 6.8 3.1 3.6 2.8 4.5 14.7 5.2 4.5 1.9 5.6 12.5 7.5 5.2 3.1 56.8 25.6 2.6 16.8 6.6 8.7 7.7 2.5 5.2 3.1 1.8 6.3 6.4 4.4 9.1 2.8 ACOT12 "Cach, STARD15, THEAL" ENSG00000172497 "Acyl-CoA thioesterase 12" Q8WYK0 5 81329996-81394179 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "liver: 100.7" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 36.2" "Cancer enriched" "Detected in single" 76 "liver cancer: 13.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA037723 Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 62: Liver - Hemostasis" "Cluster 2: Hepatocytes - Metabolism" Cytosol "Nucleoplasm, Cytokinetic bridge" "HPA037723: AB_10672606" "unprognostic (6.06e-2)" "unprognostic (1.39e-1)" "prognostic favorable (5.30e-4)" "unprognostic (7.68e-2)" "unprognostic (8.22e-2)" "unprognostic (5.68e-3)" "unprognostic (2.46e-1)" "unprognostic (6.86e-2)" "unprognostic (1.46e-2)" "unprognostic (3.07e-1)" "unprognostic (1.06e-1)" 0.0 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.5 2.7 100.7 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.0 0.5 0.3 0.5 0.3 0.3 0.6 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.8 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.0 8.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 36.2 0.5 0.0 1.2 0.0 0.0 1.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 3.4 4.2 0.0 0.0 0.0 0.4 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 ACTL6B "ACTL6, BAF53B" ENSG00000077080 "Actin like 6B" O94805 7 100643097-100656448 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 20.7;pituitary gland: 15.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 8.0;Excitatory neurons: 22.1;Horizontal cells: 6.7;Inhibitory neurons: 19.0" "Group enriched" "Detected in some" 11 "glioma: 3.9;pancreatic cancer: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 76 "SCLC-21H: 28.5;SH-SY5Y: 28.7" "Low region specificity" "Detected in all" HPA045126 Uncertain Approved "Nucleoli rim,Mitotic chromosome" Yes NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli rim, Mitotic chromosome" "HPA045126: AB_10961265" "unprognostic (3.31e-2)" "unprognostic (6.89e-2)" "unprognostic (4.59e-3)" "unprognostic (4.15e-2)" "unprognostic (1.27e-3)" "unprognostic (4.81e-3)" "unprognostic (6.00e-2)" "unprognostic (8.26e-3)" "unprognostic (1.29e-1)" "unprognostic (4.72e-3)" "unprognostic (1.28e-1)" "unprognostic (3.01e-4)" "unprognostic (1.64e-1)" "unprognostic (6.84e-2)" "unprognostic (2.01e-2)" 0.0 1.8 13.8 0.0 14.5 0.0 0.0 9.4 20.7 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 14.9 8.5 0.0 0.0 0.0 0.0 4.4 1.8 0.0 0.8 0.1 15.3 0.0 4.3 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.5 0.6 3.9 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.5 28.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 14.5 9.4 20.7 14.9 8.5 4.4 1.8 4.3 1.7 3.9 11.5 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.6 8.0 0.0 0.1 0.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 22.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.7 19.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 1.0 0.0 1.2 0.0 3.5 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.1 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 ADAMTS16 ADAMTS16s ENSG00000145536 "ADAM metallopeptidase with thrombospondin type 1 motif 16" Q8TE57 5 5140330-5320304 "Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.0;ovary: 10.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 7.3;Excitatory neurons: 44.7;Fibroblasts: 13.7;Granulosa cells: 22.2;Theca cells: 15.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 5 "cerebellum: 17.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 3.9;SuSa: 3.5;U-2197: 5.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA067668 Approved "Nucleoplasm,Nuclear membrane,Midbody ring,Mitochondria" "Secreted to extracellular matrix" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear membrane, Mitochondria" "Nucleoplasm, Midbody ring" "HPA067668: " "unprognostic (8.48e-2)" "unprognostic (1.19e-1)" "unprognostic (2.86e-2)" "unprognostic (1.98e-4)" "unprognostic (1.91e-2)" "unprognostic (5.04e-2)" "unprognostic (7.64e-2)" "unprognostic (7.80e-3)" "unprognostic (2.12e-2)" "unprognostic (5.44e-2)" "unprognostic (1.51e-2)" "unprognostic (2.18e-1)" "prognostic favorable (3.29e-5)" "unprognostic (1.20e-4)" "unprognostic (1.46e-1)" "unprognostic (4.59e-3)" "unprognostic (2.86e-3)" 5.4 0.2 1.4 0.4 1.9 0.5 0.7 17.0 2.6 1.4 0.0 0.7 0.6 1.3 1.6 1.5 0.7 6.4 0.2 3.4 0.0 3.5 0.4 0.7 0.2 0.2 0.2 10.4 4.5 0.1 0.0 0.2 0.7 0.1 0.3 1.2 0.2 0.5 0.2 0.4 0.5 1.1 0.0 0.2 0.2 0.4 0.0 0.2 0.3 0.2 0.1 1.0 0.6 1.8 1.7 1.7 1.7 0.1 0.1 0.3 0.2 0.0 0.0 0.4 0.5 0.0 1.4 0.1 2.1 0.0 3.0 0.1 0.0 0.0 0.4 0.1 0.9 0.3 2.8 0.0 0.0 0.2 0.0 0.0 0.0 3.9 0.1 0.5 0.0 0.3 0.6 0.4 0.7 0.0 0.4 0.2 1.1 0.0 1.6 0.4 2.2 0.1 0.0 0.1 0.5 0.1 0.1 0.1 0.1 3.5 0.1 0.1 0.1 2.1 3.0 5.8 1.4 0.9 0.3 0.1 3.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.4 1.9 17.0 2.6 3.4 0.0 0.2 0.2 0.7 0.0 0.0 1.8 0.7 0.0 0.6 2.6 0.0 0.0 0.0 0.0 0.6 2.0 0.7 0.4 0.5 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.2 5.0 0.1 0.0 0.0 44.7 0.0 0.0 13.7 0.5 0.5 0.0 22.2 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 2.8 0.0 0.0 0.0 1.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 6.9 1.6 0.1 0.0 0.0 0.0 0.0 0.1 15.9 0.0 0.0 ADAMTS18 ADAMTS21 ENSG00000140873 "ADAM metallopeptidase with thrombospondin type 1 motif 18" Q8TE60 16 77247813-77435034 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 11.0;placenta: 20.6" "Cell type enhanced" "Detected in some" "Adipocytes: 36.8;Granulosa cells: 15.0;Muller glia cells: 13.7;Oligodendrocytes: 16.9;Rod photoreceptor cells: 7.6" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 11.6;HUVEC TERT2: 8.0;SuSa: 10.6;TIME: 2.5;U-87 MG: 4.8" "Region enriched" "Detected in single" 5 "cerebellum: 3.3" "Low region specificity" "Detected in all" HPA044326 Uncertain Approved "Midbody,Mitotic spindle" "Secreted to extracellular matrix" Yes NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Midbody, Mitotic spindle" "HPA044326: AB_10961006" "unprognostic (1.10e-2)" "unprognostic (2.78e-1)" "unprognostic (1.38e-1)" "unprognostic (2.50e-1)" "unprognostic (8.13e-2)" "unprognostic (2.05e-2)" "unprognostic (1.09e-1)" "unprognostic (6.27e-2)" "unprognostic (2.46e-2)" "unprognostic (2.98e-1)" "unprognostic (4.11e-2)" "unprognostic (2.20e-2)" "unprognostic (8.17e-4)" "unprognostic (1.77e-5)" "unprognostic (2.17e-1)" "unprognostic (3.41e-1)" "unprognostic (2.47e-4)" 3.1 0.1 1.3 0.3 3.0 0.0 2.9 11.0 2.5 1.2 0.5 0.0 0.1 0.8 0.0 0.1 0.2 0.6 0.0 1.8 2.7 0.2 0.0 0.1 0.1 4.3 2.4 0.1 0.3 0.0 0.8 20.6 3.7 0.4 0.0 2.0 1.3 0.1 0.6 0.1 0.0 0.6 1.7 0.0 0.0 0.2 2.4 0.9 0.0 0.0 0.0 0.9 0.1 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 10.6 0.0 0.5 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.2 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 3.0 11.0 2.5 1.8 2.7 4.3 2.4 3.7 1.7 2.4 5.9 36.8 0.0 0.0 4.6 0.1 0.1 0.1 0.0 0.0 1.8 1.5 4.3 0.6 0.0 0.0 1.8 2.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 5.0 0.0 0.0 0.6 0.0 0.1 1.2 0.0 0.3 0.0 15.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 13.7 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 1.1 0.2 0.6 0.0 0.1 0.3 0.0 0.1 0.0 0.0 ADAMTS19 ENSG00000145808 "ADAM metallopeptidase with thrombospondin type 1 motif 19" 5 129460281-129738683 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 10 "brain: 3.3;cervix: 10.2;endometrium 1: 9.8;placenta: 3.7;smooth muscle: 5.9" "Group enriched" "Detected in some" 4 "Excitatory neurons: 82.6;Inhibitory neurons: 79.7;Oligodendrocytes: 31.8" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.7;testis cancer: 1.2" "Region enhanced" "Detected in some" "basal ganglia: 3.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "MCF7: 15.9;SH-SY5Y: 34.8" "Region enriched" "Detected in single" 5 "olfactory bulb: 2.6" "Low region specificity" "Detected in many" "HPA056171, HPA058438" Uncertain Approved Vesicles,Midbody "Secreted to extracellular matrix" Yes NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Midbody" "HPA056171: AB_2683054, HPA058438: AB_2683718" "unprognostic (1.14e-1)" "unprognostic (1.42e-1)" "unprognostic (1.01e-1)" "unprognostic (1.10e-3)" "unprognostic (1.09e-1)" "unprognostic (6.49e-2)" "unprognostic (3.93e-2)" "unprognostic (4.17e-2)" "unprognostic (5.99e-3)" "unprognostic (5.17e-1)" "unprognostic (1.14e-1)" "unprognostic (5.88e-2)" "unprognostic (3.06e-2)" 0.0 0.6 1.0 0.0 3.3 0.0 0.0 0.0 1.5 10.2 0.1 0.2 0.1 9.8 0.0 0.2 0.2 0.0 0.2 0.8 0.2 0.3 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.1 0.0 3.7 0.0 0.1 0.3 0.5 0.3 0.0 0.5 0.0 0.1 5.9 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.3 0.1 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 15.9 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 34.8 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 3.3 0.0 1.5 0.8 0.2 0.0 0.5 0.0 0.0 0.3 0.6 0.1 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 1.4 0.0 0.0 1.8 0.0 15.6 0.0 0.3 0.0 0.0 1.5 0.5 8.9 0.2 0.0 0.0 82.6 0.2 0.7 1.0 0.0 0.7 0.0 0.0 0.0 0.0 1.7 0.0 79.7 0.1 0.0 0.0 0.3 0.7 0.0 0.1 0.0 1.0 0.0 1.1 0.0 12.5 31.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.4 0.1 0.1 0.0 5.2 0.1 0.1 0.3 0.0 AGAP2 CENTG1 ENSG00000135439 "ArfGAP with GTPase domain, ankyrin repeat and PH domain 2" Q99490 12 57723761-57742157 "Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 219.9" "Cell type enhanced" "Detected in many" "dendritic cells: 16.4;Excitatory neurons: 22.2;Inhibitory neurons: 12.3;NK-cells: 17.5;Sertoli cells: 32.9;Smooth muscle cells: 16.2;T-cells: 16.4" "Cancer enriched" "Detected in many" 12 "glioma: 20.6" "Region enhanced" "Detected in many" "cerebral cortex: 219.9" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 40.3;Karpas-707: 39.8;RH-30: 98.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023474, HPA075831" Enhanced Supported "Nucleoplasm,Midbody ring,Cytosol" Yes NA "Cluster 35: T-regs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "Midbody ring" "HPA023474: AB_1855378, HPA075831: " "unprognostic (1.87e-1)" "unprognostic (2.46e-3)" "unprognostic (9.26e-2)" "unprognostic (5.56e-4)" "unprognostic (3.95e-1)" "unprognostic (1.14e-2)" "unprognostic (5.00e-2)" "unprognostic (2.36e-2)" "unprognostic (3.39e-1)" "unprognostic (2.80e-1)" "unprognostic (1.93e-3)" "unprognostic (4.18e-1)" "unprognostic (4.81e-9)" "unprognostic (3.30e-1)" "unprognostic (2.72e-2)" "unprognostic (3.07e-1)" "unprognostic (5.75e-2)" 6.3 2.5 85.4 10.0 69.0 14.5 1.8 0.6 219.9 0.8 0.0 2.2 2.9 2.0 0.3 2.3 1.0 4.3 23.5 162.1 0.0 0.8 1.1 3.4 16.9 0.0 0.0 1.5 3.7 1.8 7.5 2.5 0.0 1.9 1.5 4.6 2.3 0.8 15.1 3.2 5.8 1.0 0.0 11.4 3.3 1.0 0.0 15.0 2.5 9.9 11.3 3.2 1.0 38.7 7.3 10.5 19.8 5.8 0.0 0.0 11.3 4.8 0.9 0.1 0.5 1.2 6.6 18.4 1.5 0.0 3.6 4.4 0.1 0.2 0.0 20.3 3.1 20.5 1.6 3.4 0.1 21.2 40.3 0.0 0.0 0.1 0.1 8.4 0.0 21.3 0.0 39.8 0.0 12.6 37.4 13.5 3.2 2.3 10.6 15.5 98.8 13.4 0.0 6.0 5.6 20.5 2.6 3.6 4.3 0.1 2.6 14.8 11.2 5.5 9.0 10.5 3.6 16.8 10.9 9.4 9.8 13.9 9.4 3.8 0.5 0.6 2.7 0.8 2.9 1.2 2.8 3.0 0.8 0.8 1.1 1.7 3.8 1.4 0.4 0.8 4.2 1.1 85.4 69.0 0.6 219.9 162.1 0.0 0.0 0.0 0.0 0.0 0.0 38.7 3.6 3.2 1.1 0.0 5.7 0.0 0.3 0.0 0.0 10.0 0.8 0.5 5.8 1.5 0.6 0.0 0.0 0.1 16.4 0.2 0.0 0.1 0.4 0.1 0.7 4.2 0.0 2.1 22.2 0.0 0.2 0.9 2.0 0.2 2.5 0.0 1.1 0.1 1.3 8.4 12.3 0.5 0.0 2.2 1.1 1.1 0.0 3.0 0.0 1.9 3.9 0.5 17.5 5.0 1.2 0.1 0.1 0.7 11.4 0.3 0.3 0.1 0.0 2.3 32.9 2.2 16.2 0.8 0.4 0.2 0.4 0.0 16.4 0.3 0.2 0.0 AGBL5 "CCP5, FLJ21839" ENSG00000084693 "ATP/GTP binding protein like 5" Q8NDL9 2 27042364-27070622 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "parathyroid gland: 49.9;testis: 192.9" "Group enriched" "Detected in many" 6 "Early spermatids: 302.7;Late spermatids: 338.0;Spermatocytes: 156.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030981 Uncertain Supported "Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 34: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Cytokinetic bridge" "Microtubules, Cytosol" "HPA030981: AB_10611673" "unprognostic (1.29e-2)" "unprognostic (8.70e-2)" "unprognostic (2.26e-1)" "unprognostic (3.13e-3)" "unprognostic (1.95e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (6.87e-5)" "unprognostic (1.86e-1)" "unprognostic (4.34e-1)" "unprognostic (6.20e-2)" "unprognostic (1.28e-1)" "unprognostic (1.20e-1)" "unprognostic (3.41e-2)" "unprognostic (5.56e-2)" "unprognostic (2.05e-1)" "unprognostic (1.69e-2)" "unprognostic (4.50e-2)" 8.8 16.7 8.4 8.0 7.4 13.6 12.4 7.8 8.2 14.4 9.5 16.2 8.8 14.0 26.0 18.3 20.8 14.3 12.7 7.3 11.3 22.5 7.2 11.2 10.7 8.3 7.8 14.4 15.0 49.9 12.5 11.2 8.9 15.2 11.5 16.3 21.2 16.5 7.1 20.5 9.9 14.6 6.1 8.5 11.8 192.9 9.1 15.6 28.5 6.5 8.6 14.9 7.3 7.5 55.0 34.7 55.4 37.2 11.6 23.0 62.9 10.9 23.5 30.9 31.9 30.2 40.5 30.3 34.0 18.9 43.4 24.6 44.8 49.4 33.9 25.9 66.8 44.5 42.0 65.7 23.6 21.6 14.4 24.4 36.7 27.1 22.0 46.9 32.8 43.5 38.9 23.8 30.3 21.5 63.2 32.3 39.4 39.4 23.7 64.5 62.9 48.0 31.9 13.6 37.1 53.6 21.5 16.7 35.0 53.9 24.9 16.3 16.4 28.6 39.2 13.8 23.9 47.7 27.2 62.4 31.8 24.4 26.1 8.8 1.8 4.5 3.3 1.1 2.5 4.6 4.1 4.6 4.1 2.3 3.6 2.2 1.1 8.5 0.7 2.3 2.8 3.8 8.4 7.4 7.8 8.2 7.3 11.3 8.3 7.8 8.9 6.1 9.1 7.5 3.6 0.0 10.1 5.2 6.3 3.3 8.3 7.2 13.6 5.7 8.6 6.7 6.7 10.0 6.8 9.2 0.0 14.7 1.8 5.9 19.6 8.3 302.7 13.0 3.9 4.9 2.4 11.6 7.9 6.0 7.9 6.4 5.6 5.8 1.3 14.1 6.4 4.1 5.2 0.0 9.1 8.4 6.1 3.1 3.5 338.0 10.5 8.0 7.2 6.5 4.9 6.8 0.0 10.1 10.1 5.0 7.6 11.3 17.1 6.0 6.3 25.0 10.7 10.0 0.0 4.2 7.0 156.8 41.2 16.3 2.7 8.3 5.0 9.4 8.6 10.5 AIDA "C1orf80, FLJ12806" ENSG00000186063 "Axin interactor, dorsalization associated" Q96BJ3 1 222668013-222713210 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027935 Approved Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 21: B-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 41: Macrophages - Immune response" Cytosol "Microtubules, Cytokinetic bridge" "HPA027935: AB_10602226" "unprognostic (2.33e-1)" "prognostic unfavorable (7.08e-5)" "unprognostic (1.37e-1)" "unprognostic (1.43e-2)" "unprognostic (2.63e-2)" "unprognostic (7.28e-2)" "unprognostic (2.58e-2)" "unprognostic (2.26e-2)" "unprognostic (2.73e-1)" "unprognostic (4.43e-2)" "unprognostic (2.09e-3)" "unprognostic (2.08e-1)" "prognostic unfavorable (4.37e-4)" "unprognostic (1.28e-1)" "unprognostic (2.15e-1)" "unprognostic (2.17e-1)" "unprognostic (2.70e-2)" 72.3 36.1 53.6 39.1 63.8 21.9 40.2 57.1 66.5 47.8 47.1 50.0 25.3 36.1 56.1 45.2 31.3 40.8 45.8 51.7 62.0 39.3 49.0 46.2 51.2 63.0 58.4 40.6 32.5 32.5 21.4 47.8 62.8 35.1 36.1 19.4 28.0 42.1 28.4 26.6 28.9 54.2 58.9 37.4 28.2 44.3 58.5 33.8 37.5 49.7 52.9 47.2 31.2 69.6 74.3 56.2 65.5 70.4 181.2 169.9 71.4 135.7 145.0 95.1 87.0 64.3 62.0 39.5 67.2 161.7 73.4 44.8 81.4 89.9 115.4 59.6 30.0 50.4 64.2 61.9 95.2 62.5 28.4 104.0 78.9 113.4 108.9 102.4 117.8 49.6 77.1 54.3 180.8 27.6 40.9 38.4 163.6 83.9 118.8 43.8 183.9 57.9 110.9 49.7 43.1 72.1 91.0 53.4 83.8 100.3 43.5 38.5 94.1 127.4 62.9 124.9 162.7 40.3 80.4 35.2 118.1 38.7 128.0 5.7 2.8 2.9 5.7 4.4 4.8 14.2 7.2 6.2 2.5 13.8 7.4 5.8 1.6 3.5 5.0 7.2 10.2 4.1 53.6 63.8 57.1 66.5 51.7 62.0 63.0 58.4 62.8 58.9 58.5 69.6 80.2 22.4 49.9 6.5 57.9 32.5 36.2 19.8 20.5 18.8 20.8 18.0 8.6 27.1 18.7 33.1 33.3 20.6 46.5 19.0 29.4 38.6 20.4 27.1 48.9 52.4 36.1 46.7 8.9 37.9 55.0 52.6 12.8 46.6 3.8 32.4 43.9 36.9 31.5 23.5 11.1 22.4 22.4 37.8 40.2 23.8 60.3 42.5 37.4 30.9 58.9 32.1 38.1 10.6 10.0 51.1 19.8 50.8 32.1 61.2 24.4 54.4 32.8 13.8 32.9 66.1 43.9 35.3 17.9 26.6 30.3 9.0 28.0 32.0 17.8 33.7 AKAP10 "D-AKAP2, MGC9414, PRKA10" ENSG00000108599 "A-kinase anchoring protein 10" O43572 17 19904302-19978343 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 78.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SuSa: 84.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028901 Approved Supported "Plasma membrane,Cytosol" Yes No "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" "HPA028901: AB_10602227" "unprognostic (2.17e-2)" "unprognostic (3.48e-2)" "unprognostic (5.33e-1)" "unprognostic (1.40e-1)" "unprognostic (1.50e-1)" "unprognostic (5.51e-2)" "unprognostic (1.59e-3)" "unprognostic (3.88e-1)" "unprognostic (7.69e-3)" "unprognostic (1.89e-1)" "unprognostic (3.59e-2)" "unprognostic (3.21e-2)" "unprognostic (3.21e-2)" "unprognostic (2.49e-2)" "unprognostic (7.15e-2)" "unprognostic (2.16e-2)" "unprognostic (5.20e-2)" 11.4 13.3 10.5 12.3 12.4 10.6 12.3 11.4 13.6 11.5 15.1 11.4 9.5 12.4 8.8 10.6 10.4 10.7 7.4 11.3 11.6 13.1 8.1 11.0 16.0 9.9 10.7 13.5 8.4 15.1 7.5 12.2 10.6 10.9 11.6 15.3 9.8 11.7 7.2 9.5 10.1 13.3 10.4 14.9 11.1 14.2 13.8 14.1 15.1 9.4 12.5 11.3 10.2 14.7 18.1 21.3 13.9 9.7 18.0 22.5 25.7 20.6 21.9 22.4 26.7 23.2 10.6 15.4 13.6 16.4 19.4 18.8 18.1 17.2 30.4 12.8 15.4 13.2 20.2 11.4 17.0 9.7 20.7 19.1 21.1 20.5 25.1 25.0 18.3 18.5 8.6 7.5 23.6 13.1 18.1 14.3 9.1 25.1 7.2 11.8 45.5 8.1 18.7 11.3 4.7 14.1 23.6 11.0 19.7 84.8 26.7 10.7 16.1 17.2 14.2 14.8 19.3 9.3 10.7 18.8 22.8 11.5 17.0 4.9 9.7 12.6 8.6 14.4 8.0 8.4 8.4 9.4 8.5 9.2 10.0 8.9 33.8 7.6 13.9 6.3 7.1 4.3 10.5 12.4 11.4 13.6 11.3 11.6 9.9 10.7 10.6 10.4 13.8 14.7 13.4 3.2 12.3 71.2 24.4 7.0 9.7 8.9 10.2 24.6 11.1 9.0 8.4 21.5 11.9 5.5 16.7 14.9 16.8 15.8 1.9 9.9 12.8 11.0 14.8 12.6 7.2 15.2 55.1 7.2 11.1 11.7 14.8 10.8 10.1 18.0 16.8 13.6 16.5 33.7 54.6 9.9 12.2 35.1 10.5 13.9 15.2 21.4 5.4 61.8 32.3 11.7 25.7 51.8 78.5 7.9 15.2 13.9 11.2 15.6 14.6 5.7 15.3 23.2 19.7 10.5 11.2 23.1 23.6 11.0 7.7 14.0 19.0 15.6 11.8 12.1 AKNAD1 "C1orf62, MGC26989" ENSG00000162641 "AKNA domain containing 1" Q5T1N1 1 108815898-108963484 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "testis: 4.8" "Cell type enriched" "Detected in some" 4 "Early spermatids: 80.6" "Cancer enhanced" "Detected in single" "glioma: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 1.1;hTCEpi: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030270, HPA030271, HPA030272" Uncertain Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 78: Testis - Spermatogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "Microtubules, Cytokinetic bridge" "HPA030270: AB_10610980, HPA030271: AB_10600873, HPA030272: AB_10601342" "unprognostic (4.93e-2)" "unprognostic (1.72e-1)" "unprognostic (5.52e-2)" "unprognostic (2.00e-3)" "unprognostic (7.22e-2)" "unprognostic (1.08e-1)" "unprognostic (1.09e-5)" "unprognostic (8.15e-2)" "unprognostic (5.95e-2)" "unprognostic (2.83e-2)" "unprognostic (1.89e-1)" "unprognostic (2.24e-1)" "unprognostic (3.00e-8)" "unprognostic (1.08e-1)" "unprognostic (4.69e-2)" "unprognostic (5.75e-2)" "unprognostic (8.22e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.8 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.7 0.0 0.0 1.6 0.0 1.5 0.1 0.0 1.8 2.5 0.5 0.9 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.2 80.6 0.3 5.1 1.4 0.0 0.0 1.0 0.2 0.8 3.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 1.4 0.7 0.0 0.0 0.3 17.8 2.5 0.1 1.8 0.0 0.0 0.4 0.0 3.5 3.1 0.2 0.0 1.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 8.2 0.9 0.6 1.4 0.1 0.1 0.7 0.1 0.7 0.5 0.0 AL031681.2 ENSG00000288000 "Novel protein" 20 43458054-43541881 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059648 Approved "Nucleoplasm,Nuclear bodies,Midbody ring" Yes NA Nucleoplasm "Nuclear bodies, Midbody ring" "HPA059648: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AL592490.1 ENSG00000197991 "Novel protein" 13 61409858-61427849 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "Alveolar cells type 1: 3.2;Alveolar cells type 2: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA062669 Approved "Vesicles,Cytokinetic bridge" Yes NA "Cluster 11: Alveolar cells - Smell perception" Vesicles "Cytokinetic bridge" "HPA062669: AB_2732687" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ALDH7A1 "ATQ1, EPD, PDE" ENSG00000164904 "Aldehyde dehydrogenase 7 family member A1" P49419 5 126531200-126595362 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 162.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 414.1;Proximal tubular cells: 302.1;Syncytiotrophoblasts: 222.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 6.4" "Lineage enriched" "Detected in many" 5 "dendritic cells: 6.4" "Cell line enhanced" "Detected in many" "HBEC3-KT: 256.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023296, HPA053675" Enhanced Supported Mitochondria,Cytosol Yes No 430000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria Cytosol "HPA023296: AB_1844738, HPA053675: " "unprognostic (1.37e-1)" "unprognostic (9.67e-2)" "unprognostic (2.07e-2)" "unprognostic (2.20e-2)" "unprognostic (4.15e-2)" "unprognostic (1.32e-1)" "unprognostic (1.58e-3)" "unprognostic (9.49e-3)" "unprognostic (7.61e-2)" "unprognostic (7.08e-2)" "unprognostic (2.10e-1)" "unprognostic (1.33e-1)" "prognostic favorable (3.08e-4)" "unprognostic (1.51e-1)" "unprognostic (3.70e-1)" "unprognostic (3.10e-3)" "unprognostic (4.93e-2)" 23.7 38.3 46.6 9.1 47.6 1.8 47.1 43.7 45.8 32.7 40.7 29.5 23.7 25.1 8.8 35.9 28.8 19.1 27.9 44.7 43.2 115.1 162.2 15.7 8.6 43.1 43.5 65.3 27.0 34.0 8.8 44.9 42.6 42.0 27.4 19.7 40.6 27.9 12.2 29.4 21.0 23.6 44.8 7.0 23.6 12.3 44.0 18.3 47.6 26.5 17.1 18.1 20.9 45.2 64.9 41.9 116.6 193.4 95.5 56.4 147.8 76.1 93.4 86.5 110.5 118.6 60.7 0.0 75.5 60.0 36.1 47.1 36.5 256.2 78.8 0.1 44.6 12.3 63.1 102.1 46.3 0.2 0.0 69.0 59.2 67.3 47.7 64.2 70.0 0.0 0.0 0.1 77.1 42.1 2.6 0.3 79.4 47.5 35.2 38.9 131.8 0.0 81.2 48.4 39.4 47.2 0.0 41.1 44.7 89.0 75.2 2.7 86.1 24.8 75.6 28.8 53.1 0.1 0.1 0.4 13.4 0.2 40.6 0.7 0.2 0.1 0.1 0.0 0.2 0.8 0.2 0.1 1.8 0.6 1.2 0.6 0.1 0.1 0.0 6.4 0.0 0.4 46.6 47.6 43.7 45.8 44.7 43.2 43.1 43.5 42.6 44.8 44.0 45.2 17.6 16.0 29.3 99.3 5.0 25.9 59.5 110.0 87.0 23.6 40.6 91.1 39.9 27.1 43.5 42.3 22.9 414.1 3.7 15.2 76.3 43.5 31.4 18.7 44.3 19.1 21.7 5.2 16.0 13.8 107.8 34.0 27.0 21.4 7.0 50.4 18.9 74.6 51.1 25.2 21.5 25.9 20.3 9.4 7.6 41.7 25.4 9.1 55.2 12.2 7.5 102.1 0.0 41.7 30.0 12.6 15.6 37.2 2.0 27.5 23.4 302.1 23.4 13.6 19.7 19.4 25.8 1.0 5.1 59.2 16.1 222.3 4.6 39.3 46.4 50.4 ALDOC ENSG00000109107 "Aldolase, fructose-bisphosphate C" P09972 17 28573115-28576948 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1384.6;choroid plexus: 589.6;retina: 1183.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 112.5;Horizontal cells: 274.2;Muller glia cells: 127.1;Proximal enterocytes: 120.0;Rod photoreceptor cells: 348.5" "Cancer enriched" "Detected in all" 6 "glioma: 128.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 250.9;U-266/70: 161.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003282, CAB020828, HPA067442" Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" Yes No 150000000 "Cluster 20: T-cells - T-cell receptor" "Cluster 77: Retina - Visual perception" "Cluster 25: RPMI-8226 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nucleoli fibrillar center" "Vesicles, Cytosol" "CAB020828: , HPA003282: AB_1078130, HPA067442: " "unprognostic (2.90e-1)" "unprognostic (4.45e-3)" "unprognostic (5.69e-3)" "unprognostic (1.43e-1)" "unprognostic (3.56e-1)" "prognostic unfavorable (9.80e-4)" "unprognostic (1.03e-1)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" "unprognostic (6.03e-3)" "unprognostic (3.90e-1)" "unprognostic (3.24e-2)" "prognostic unfavorable (1.29e-7)" "unprognostic (1.28e-1)" "unprognostic (2.00e-1)" "unprognostic (2.74e-2)" "unprognostic (1.23e-1)" 87.0 24.3 953.6 12.7 909.7 23.6 42.5 1238.3 1162.3 39.3 589.6 18.5 18.7 17.9 10.9 40.8 14.3 10.9 285.5 955.7 958.0 16.8 98.3 13.7 19.3 1297.5 962.6 39.1 4.9 12.1 30.6 4.1 1384.6 18.9 14.7 1183.1 19.9 15.8 4.8 74.5 43.9 12.4 926.9 24.4 23.3 14.2 1090.2 9.6 7.4 8.1 30.5 19.0 47.0 886.1 29.9 2.1 13.7 55.7 29.9 32.9 2.9 16.7 37.7 12.9 76.0 17.9 3.0 14.9 17.3 15.5 3.3 36.9 10.3 102.3 23.4 12.4 8.9 28.3 11.6 30.4 25.8 10.0 29.2 27.8 13.9 1.5 24.0 1.7 5.3 29.7 19.3 71.9 10.7 15.1 11.9 32.0 20.8 6.7 15.3 9.5 1.6 250.9 1.9 4.3 36.2 61.9 9.1 67.3 0.5 20.8 36.6 21.2 3.5 1.2 5.3 2.1 2.4 161.0 51.4 10.9 105.2 28.0 1.9 0.5 7.4 3.0 21.6 8.7 30.6 24.0 29.5 17.8 9.4 25.1 37.7 28.4 18.0 29.4 5.3 4.6 40.9 19.0 953.6 909.7 1238.3 1162.3 955.7 958.0 1297.5 962.6 1384.6 926.9 1090.2 886.1 4.2 0.0 15.8 97.6 9.8 7.5 20.3 80.5 8.6 112.5 9.0 11.0 22.1 11.5 29.3 7.3 106.3 1.1 9.5 31.7 3.9 21.9 0.9 1.0 3.0 11.3 21.6 3.2 19.2 10.2 6.5 5.8 6.6 1.2 13.3 4.9 14.3 93.1 5.4 274.2 41.3 12.9 28.5 4.4 5.3 1.3 9.3 3.1 24.9 21.5 34.1 127.1 12.3 26.7 16.8 12.4 12.4 10.1 2.6 6.1 120.0 2.1 11.8 348.5 13.1 6.4 10.1 0.3 3.2 7.9 10.9 1.5 17.0 11.7 5.1 7.8 ANAPC11 "APC11, Apc11p, HSPC214, MGC882" ENSG00000141552 "Anaphase promoting complex subunit 11" Q9NYG5 17 81890790-81900991 "Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1161.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA021989, HPA027838" Approved Enhanced Nucleoplasm,Nucleoli Yes No "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm Nucleoli "HPA021989: AB_1844915, HPA027838: AB_10600978" "unprognostic (9.00e-3)" "unprognostic (1.24e-2)" "unprognostic (3.76e-1)" "unprognostic (4.93e-2)" "unprognostic (8.76e-2)" "unprognostic (1.67e-1)" "unprognostic (5.13e-2)" "unprognostic (8.20e-2)" "unprognostic (1.65e-1)" "unprognostic (2.17e-3)" "unprognostic (2.22e-2)" "unprognostic (1.08e-1)" "unprognostic (4.76e-2)" "unprognostic (8.07e-2)" "unprognostic (9.08e-2)" "unprognostic (2.51e-2)" "unprognostic (3.16e-1)" 112.1 120.5 104.8 52.1 108.6 109.3 103.4 110.9 149.5 85.9 100.7 126.0 61.0 86.4 39.0 125.8 80.3 58.0 231.3 106.4 106.8 127.3 185.7 89.3 73.0 110.0 105.1 76.4 108.1 59.0 92.0 54.8 105.0 105.7 27.3 19.3 117.6 42.0 272.8 99.7 83.4 36.5 110.4 86.7 117.9 189.7 113.0 50.1 90.6 126.5 34.0 95.9 94.7 118.1 262.4 605.0 139.0 209.7 118.7 132.8 164.3 123.4 100.6 111.4 127.1 248.6 226.9 82.1 133.3 114.4 121.8 148.9 58.1 166.4 40.5 122.5 437.1 126.8 257.9 379.0 131.3 95.3 103.6 145.6 151.8 120.4 98.2 73.4 184.9 111.9 173.7 233.8 120.8 474.1 225.5 150.6 131.2 259.2 448.7 92.3 136.2 168.0 104.9 229.3 175.8 282.6 133.5 205.7 253.8 96.7 254.1 222.7 108.4 215.0 169.5 229.4 234.1 110.5 52.1 107.0 228.7 144.5 177.7 495.1 419.8 418.8 229.7 359.9 218.7 309.0 232.0 252.9 348.0 296.2 223.0 212.3 212.1 258.5 345.4 581.1 297.9 506.0 104.8 108.6 110.9 149.5 106.4 106.8 110.0 105.1 105.0 110.4 113.0 118.1 137.2 128.2 157.2 11.4 110.5 148.6 215.0 406.1 145.7 59.5 272.5 332.7 360.2 201.6 272.3 198.6 20.9 467.8 119.5 239.6 522.3 260.6 451.9 157.0 151.3 152.9 190.3 201.6 9.8 337.7 524.6 182.9 124.4 169.5 108.3 158.3 159.2 496.4 448.2 33.7 10.2 272.6 319.4 174.6 194.3 1161.0 181.7 170.1 261.5 13.1 251.4 227.7 176.1 7.1 17.0 324.3 274.0 164.7 226.8 334.2 290.7 548.0 199.8 78.9 105.2 115.9 245.0 435.8 252.5 257.4 186.7 508.7 117.3 156.0 271.4 307.0 ANG "RAA1, RNASE5" ENSG00000214274 Angiogenin P03950 14 20684177-20698971 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Differentiation, Stress response" "Developmental protein, DNA-binding, Endonuclease, Hydrolase, Nuclease, Protein synthesis inhibitor" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 52 "liver: 3018.1" "Cell type enriched" "Detected in many" 24 "Hepatocytes: 4816.3" "Cancer enriched" "Detected in all" 17 "liver cancer: 279.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.5;myeloid DC: 14.5" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Hep G2: 152.2;OE19: 116.1" "Low region specificity" "Detected in all" HPA055896 Approved "Nucleoli,Nucleoli rim,Mitotic chromosome,Actin filaments" "Secreted to blood" Yes No 308000000 410000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Nucleoli, Nucleoli rim, Mitotic chromosome" "Actin filaments" "HPA055896: " "unprognostic (2.50e-2)" "unprognostic (1.82e-1)" "unprognostic (9.77e-2)" "prognostic favorable (6.85e-4)" "unprognostic (5.71e-3)" "unprognostic (6.99e-2)" "prognostic favorable (7.83e-5)" "unprognostic (1.16e-1)" "unprognostic (3.20e-3)" "unprognostic (9.19e-3)" "unprognostic (1.31e-1)" "unprognostic (3.69e-1)" "unprognostic (6.65e-2)" "unprognostic (1.03e-1)" "unprognostic (3.39e-1)" "unprognostic (2.00e-1)" "unprognostic (3.09e-1)" 37.6 3.0 3.6 6.0 3.5 1.0 37.8 3.5 4.9 38.2 5.6 32.6 23.2 23.4 17.9 9.8 30.5 28.5 16.9 3.6 4.9 18.4 3018.1 18.5 3.5 4.5 4.2 58.1 30.8 5.3 5.0 3.8 4.3 32.7 45.7 2.2 52.6 13.3 6.2 27.4 27.1 10.4 4.5 7.4 58.2 10.2 3.7 1.5 8.8 10.5 4.1 24.8 31.4 4.8 3.7 9.9 2.3 0.0 23.9 27.8 0.3 4.8 8.8 1.1 4.0 5.9 5.1 0.4 1.5 12.0 8.0 3.8 2.8 3.1 1.3 18.4 3.8 0.9 5.1 152.2 5.0 4.0 0.5 22.2 2.5 1.5 5.1 11.8 5.7 4.2 0.2 27.0 3.5 0.7 0.9 1.2 0.7 116.1 10.7 0.7 3.9 11.3 2.3 2.9 0.0 0.4 4.6 1.7 6.5 5.1 4.0 0.7 6.0 1.9 2.8 1.7 0.7 5.9 4.8 0.5 3.2 2.0 5.0 0.0 24.5 0.0 0.6 2.9 0.4 5.8 1.2 1.1 14.5 4.9 0.3 0.2 0.4 0.0 0.1 2.3 0.8 7.1 3.6 3.5 3.5 4.9 3.6 4.9 4.5 4.2 4.3 4.5 3.7 4.8 9.7 28.9 17.7 0.0 9.7 27.1 43.3 39.2 14.2 0.1 33.8 24.8 0.8 194.5 24.6 11.0 0.0 1.6 0.7 32.5 11.7 40.0 1.0 6.2 9.7 11.0 71.0 27.8 0.0 31.6 5.3 48.8 56.1 24.9 0.0 10.7 62.4 4816.3 15.9 0.0 0.0 171.9 12.2 95.9 18.7 2.9 71.1 13.8 23.2 0.0 4.9 10.1 0.0 0.0 0.0 21.6 33.3 24.0 11.7 43.7 91.3 61.2 76.5 0.6 13.1 29.7 17.7 1.0 1.3 9.4 52.4 9.3 5.6 0.5 51.6 39.2 ANKRD54 LIAR ENSG00000100124 "Ankyrin repeat domain 54" Q6NXT1 22 37830855-37849327 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071287 Approved Approved Nucleoplasm,Microtubules,Midbody Yes No "Cluster 15: NK-cells - Transcription" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" "Microtubules, Midbody" Nucleoplasm "HPA071287: AB_2686380" "unprognostic (5.36e-2)" "prognostic favorable (2.06e-4)" "unprognostic (1.02e-1)" "prognostic favorable (7.38e-5)" "unprognostic (1.14e-1)" "unprognostic (1.50e-1)" "unprognostic (1.65e-2)" "unprognostic (1.77e-2)" "unprognostic (1.06e-1)" "unprognostic (3.41e-2)" "prognostic favorable (6.16e-4)" "unprognostic (2.53e-1)" "unprognostic (6.33e-2)" "unprognostic (1.13e-1)" "unprognostic (5.07e-2)" "unprognostic (1.89e-1)" "unprognostic (3.02e-3)" 8.6 18.7 22.4 5.9 20.8 6.9 9.1 22.6 23.3 13.0 28.7 16.4 7.1 12.9 7.8 14.0 23.8 6.3 12.4 23.0 26.2 14.9 15.6 8.4 6.4 22.6 24.7 17.8 18.1 11.7 19.2 5.4 21.6 13.7 6.6 6.3 13.9 11.0 12.6 11.3 8.9 9.5 22.0 9.2 10.9 30.9 26.1 10.4 13.8 8.7 7.2 14.0 10.9 20.3 18.5 18.6 15.4 23.0 19.9 11.3 8.1 24.8 19.2 41.1 25.2 11.8 7.3 17.8 10.1 16.5 13.3 16.4 19.5 14.1 19.9 14.2 39.5 9.3 17.3 28.3 17.7 17.8 20.8 10.1 14.2 22.6 13.3 10.3 25.5 13.1 11.9 12.7 19.1 19.8 17.6 21.1 4.4 24.5 16.5 20.2 18.3 11.3 23.2 6.4 26.4 14.1 20.7 18.8 30.8 7.0 19.3 28.0 15.1 24.5 25.6 12.9 18.6 13.3 11.7 14.3 20.1 15.1 17.9 3.5 4.5 2.2 5.4 5.5 5.4 3.9 5.1 4.0 5.7 5.2 5.3 2.6 2.7 10.2 9.3 5.3 2.4 3.3 22.4 20.8 22.6 23.3 23.0 26.2 22.6 24.7 21.6 22.0 26.1 20.3 8.4 12.8 14.5 11.8 14.4 15.8 11.0 12.4 12.0 18.3 16.9 15.6 8.1 24.3 12.2 18.4 29.2 20.9 14.0 19.9 39.2 17.1 6.4 47.8 12.6 10.9 9.0 12.8 9.4 14.7 17.7 12.3 12.2 8.5 9.5 23.3 13.6 12.0 13.2 26.9 9.4 14.3 12.2 12.5 10.7 7.7 18.0 8.8 10.6 2.8 9.2 18.5 17.5 13.6 8.6 11.3 15.3 21.4 8.4 11.4 19.2 22.0 48.2 23.2 6.6 13.1 13.4 65.6 42.1 12.7 17.6 16.8 13.3 25.4 20.7 9.9 ANLN "ANILLIN, scra, Scraps" ENSG00000011426 "Anillin actin binding protein" Q9NQW6 7 36389821-36453791 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 266.0" "Group enriched" "Detected in many" 5 "Early spermatids: 156.4;Oligodendrocytes: 441.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HBF TERT88: 655.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005680, CAB033902, HPA050556, CAB062547, CAB068175" Enhanced Enhanced Nucleoplasm,Midbody Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Midbody "CAB033902: AB_2058302, CAB062547: AB_2665622, CAB068175: AB_2665623, HPA005680: AB_2667388, HPA050556: AB_2681175" "unprognostic (4.23e-2)" "unprognostic (1.59e-3)" "unprognostic (1.49e-1)" "prognostic unfavorable (1.73e-4)" "unprognostic (1.67e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (5.97e-7)" "prognostic unfavorable (6.99e-5)" "unprognostic (2.69e-2)" "unprognostic (3.66e-2)" "prognostic unfavorable (2.00e-6)" "unprognostic (3.13e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.29e-2)" "unprognostic (1.34e-1)" "unprognostic (2.94e-2)" "unprognostic (4.04e-3)" 1.2 0.7 59.8 5.2 134.5 36.4 2.0 125.1 72.7 1.8 18.4 6.0 4.4 1.8 0.2 10.4 0.9 2.1 0.8 59.3 83.6 0.4 1.2 1.4 6.7 162.3 106.5 0.9 0.6 0.2 0.2 8.9 160.2 0.9 8.0 0.3 1.7 0.4 0.3 13.6 4.3 14.9 99.2 1.2 4.8 12.4 102.3 16.0 0.8 0.3 9.5 3.2 3.2 266.0 476.1 96.5 79.3 61.0 10.7 26.9 85.6 292.5 169.3 344.4 256.0 66.4 142.7 23.9 82.1 148.6 182.8 237.0 63.4 170.7 655.4 16.1 46.0 32.7 104.8 55.8 1.7 47.3 36.7 6.0 7.7 225.3 147.2 40.8 109.3 31.2 69.6 48.8 284.4 71.0 40.0 54.8 88.5 71.9 102.3 29.1 238.2 15.9 76.5 76.5 33.5 39.5 154.1 175.8 26.1 109.6 119.0 53.6 104.5 214.2 239.0 127.6 346.6 20.1 34.2 43.2 72.9 74.9 460.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.3 59.8 134.5 125.1 72.7 59.3 83.6 162.3 106.5 160.2 99.2 102.3 266.0 0.4 0.0 1.1 2.3 1.0 14.1 1.9 8.3 7.4 0.0 1.9 2.0 0.6 0.0 3.2 0.0 0.0 13.8 1.1 2.8 0.0 0.7 156.4 18.9 3.2 1.9 0.0 35.3 3.4 0.2 23.2 6.9 10.2 12.8 0.0 15.4 1.1 0.5 9.8 0.0 5.7 3.4 6.1 1.6 5.9 53.3 1.2 2.7 0.0 0.0 0.0 0.0 0.0 1.5 441.3 0.6 0.1 0.0 8.8 1.6 0.8 0.3 10.4 0.0 0.0 0.4 5.2 20.0 17.7 27.1 9.2 2.9 2.6 1.7 6.0 3.3 AP002495.1 ENSG00000254469 "XRCC1 N-terminal domain containing 1-like" Q6ZNB5 11 71865504-71928665 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Cytotrophoblasts: 6.0;Extravillous trophoblasts: 2.2;Hofbauer cells: 2.0;Respiratory ciliated cells: 1.5;Syncytiotrophoblasts: 2.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051121, HPA051124" Uncertain Enhanced "Nucleoli,Mitotic chromosome" Yes NA "Cluster 20: T-cells - T-cell receptor" "Cluster 34: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoli "Mitotic chromosome" "HPA051121: AB_2681349, HPA051124: " "unprognostic (1.66e-1)" "unprognostic (1.19e-2)" "unprognostic (2.23e-1)" "unprognostic (1.73e-2)" "unprognostic (2.39e-1)" "unprognostic (2.42e-1)" "unprognostic (2.32e-3)" "unprognostic (9.79e-4)" "unprognostic (5.91e-3)" "unprognostic (5.04e-3)" "unprognostic (7.21e-2)" "unprognostic (2.23e-1)" "unprognostic (1.92e-2)" "unprognostic (1.33e-2)" "unprognostic (2.07e-1)" "unprognostic (3.60e-1)" "unprognostic (3.12e-3)" 1.9 2.1 1.9 2.2 2.8 4.7 3.2 4.3 2.6 2.8 2.8 2.2 2.6 3.7 5.3 2.6 2.4 2.1 2.1 1.7 2.2 2.9 2.2 1.8 4.2 2.5 1.5 4.6 3.1 2.9 2.5 2.0 2.4 3.1 3.5 7.3 2.2 2.8 1.6 4.2 2.6 2.4 0.6 2.9 2.4 3.3 2.8 3.2 3.2 1.5 3.4 2.3 2.2 5.0 2.6 6.2 4.7 4.5 1.8 1.6 3.1 2.9 2.3 3.1 3.0 6.5 6.4 5.8 2.6 2.0 3.9 8.4 4.9 3.3 3.2 8.4 4.5 9.4 7.7 4.2 1.1 4.2 3.1 2.2 1.6 5.2 3.6 2.6 4.9 8.0 6.3 7.6 3.0 4.9 4.8 3.5 4.9 9.6 4.5 3.6 16.3 4.0 3.5 3.1 6.9 6.6 4.6 4.1 9.2 3.3 5.1 2.3 4.6 2.5 4.1 4.9 1.9 5.5 8.4 7.0 4.0 4.6 3.7 2.7 1.9 1.7 2.9 3.0 1.7 2.5 5.1 3.8 2.2 3.3 4.8 4.1 2.0 1.2 1.9 4.8 4.9 1.9 1.9 2.8 4.3 2.6 1.7 2.2 2.5 1.5 2.4 0.6 2.8 5.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.2 0.0 0.0 0.0 AP002748.5 ENSG00000256349 "Novel protein" 11 66509079-66533613 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.9;choroid plexus: 1.9;retina: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "NTERA-2: 9.7;THP-1: 2.8" HPA058283 Uncertain Approved Midbody Yes NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" Midbody "HPA058283: AB_2683667" 0.0 0.1 2.1 0.0 2.2 0.0 0.2 1.9 2.9 0.0 1.9 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.0 2.3 0.4 0.2 0.2 0.2 2.3 2.1 0.0 0.9 0.2 0.0 0.2 2.3 0.1 0.0 2.2 0.0 0.0 0.1 0.0 0.0 0.2 2.3 0.1 0.1 0.0 2.4 0.1 0.1 0.0 0.0 0.1 0.0 2.5 0.6 0.0 0.4 0.0 0.0 0.0 0.3 0.3 0.4 0.1 0.0 0.0 0.1 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.7 0.0 0.2 0.6 0.2 0.0 0.1 1.1 0.1 0.0 1.3 0.1 0.4 0.0 0.6 0.3 0.6 9.7 0.8 0.0 0.8 0.0 0.0 0.7 1.4 0.2 0.1 0.2 0.5 0.4 0.2 0.9 2.8 0.1 0.4 0.2 0.0 0.0 0.0 0.2 0.4 0.3 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 2.2 1.9 2.9 2.0 2.3 2.3 2.1 2.3 2.3 2.4 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 APC2 APCL ENSG00000115266 "APC regulator of WNT signaling pathway 2" O95996 19 1446302-1473244 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 64.5" "Cell type enhanced" "Detected in some" "Astrocytes: 142.4;Bipolar cells: 50.4;Excitatory neurons: 26.8;Horizontal cells: 45.4;Inhibitory neurons: 27.5;Muller glia cells: 29.4;Oligodendrocyte precursor cells: 28.1" "Cancer enriched" "Detected in some" 27 "glioma: 17.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.8;SCLC-21H: 9.3;SH-SY5Y: 31.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078002 Supported "Cytokinetic bridge,Midbody,Cytosol" Yes No "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Cytokinetic bridge, Midbody" Cytosol "HPA078002: AB_2686874" "unprognostic (1.78e-3)" "unprognostic (1.65e-1)" "unprognostic (2.88e-5)" "unprognostic (3.64e-2)" "unprognostic (3.59e-1)" "unprognostic (1.52e-2)" "unprognostic (1.00e-1)" "unprognostic (1.32e-1)" "unprognostic (1.86e-1)" "unprognostic (1.38e-2)" "unprognostic (1.30e-2)" "unprognostic (3.45e-2)" "unprognostic (9.49e-3)" "unprognostic (7.39e-2)" "unprognostic (3.70e-2)" "unprognostic (4.99e-2)" "unprognostic (1.98e-3)" 0.1 2.4 41.5 0.0 27.3 0.0 0.0 41.4 42.4 0.1 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.1 0.3 37.1 20.8 0.0 0.0 0.0 0.0 64.5 42.3 0.0 0.3 0.0 6.2 0.0 54.9 0.1 0.0 2.7 0.2 0.0 0.2 0.1 0.4 0.1 38.3 0.0 0.3 1.0 54.6 0.0 0.1 0.0 0.0 0.1 0.2 49.0 0.2 0.6 7.8 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.1 0.0 0.5 0.2 0.1 0.0 0.0 1.0 0.1 0.0 0.4 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.6 0.0 0.0 9.3 31.7 1.1 0.0 0.5 0.1 0.1 0.0 0.0 0.4 0.6 0.1 0.1 1.7 0.5 0.2 0.7 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.5 27.3 41.4 42.4 37.1 20.8 64.5 42.3 54.9 38.3 54.6 49.0 0.3 0.0 0.0 142.4 0.3 0.0 0.2 0.2 1.2 50.4 0.4 0.4 3.4 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.1 0.5 0.5 0.5 0.0 0.0 26.8 0.0 0.1 0.3 0.0 0.6 0.0 0.2 0.0 0.0 0.1 45.4 27.5 0.0 0.0 0.0 0.0 0.7 0.3 0.1 0.0 3.7 0.0 29.4 2.1 28.1 17.8 0.0 0.0 0.7 0.0 0.1 0.2 0.2 0.0 11.1 0.0 0.6 0.4 0.4 0.7 2.4 0.0 0.0 0.3 0.2 0.1 0.2 APEX1 "APE, APE-1, APEN, APEX, APX, HAP1, REF-1, REF1" ENSG00000100823 "Apurinic/apyrimidinic endodeoxyribonuclease 1" P27695 14 20455191-20457772 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Activator, DNA-binding, Endonuclease, Exonuclease, Hydrolase, Nuclease, Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000956, HPA002564, CAB004294, CAB047307" Supported Supported Nucleoplasm Yes No 330000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" Nucleoplasm "CAB004294: AB_626685, CAB047307: , HPA000956: AB_2666158, HPA002564: AB_1078174" "unprognostic (2.80e-3)" "unprognostic (1.39e-1)" "unprognostic (1.55e-2)" "unprognostic (4.74e-3)" "unprognostic (1.97e-2)" "unprognostic (5.88e-2)" "prognostic unfavorable (7.82e-5)" "unprognostic (4.21e-2)" "unprognostic (3.14e-2)" "unprognostic (2.46e-2)" "unprognostic (2.42e-2)" "unprognostic (1.68e-1)" "unprognostic (1.38e-1)" "unprognostic (1.22e-1)" "unprognostic (1.83e-2)" "unprognostic (2.54e-1)" "unprognostic (7.08e-2)" 83.9 103.6 56.9 82.8 58.1 154.9 103.2 60.0 67.5 80.4 57.9 89.1 107.5 97.2 66.5 80.5 99.1 79.7 76.6 57.5 60.3 82.8 104.6 61.0 112.4 58.9 58.3 146.3 92.2 88.3 39.3 57.3 59.5 69.3 92.7 52.9 66.0 80.2 102.9 83.4 73.0 95.7 59.5 68.9 85.4 21.5 60.1 125.0 93.2 71.9 121.2 103.8 65.8 62.6 249.3 296.8 267.8 247.2 180.9 259.3 226.5 227.3 245.7 333.3 287.4 216.9 240.7 477.9 198.4 176.4 178.1 262.5 317.5 242.1 304.8 214.7 135.9 195.5 162.8 368.9 189.5 623.1 193.2 270.6 261.6 217.6 212.6 267.2 282.3 193.9 228.4 153.6 270.7 240.0 404.7 264.7 260.3 282.4 269.5 441.5 297.7 200.8 281.7 327.1 315.2 201.8 248.5 305.2 253.1 185.0 186.4 276.7 186.0 175.0 292.8 177.9 216.6 203.1 375.8 327.7 77.8 390.7 224.7 0.9 106.7 7.5 79.6 93.4 108.4 154.8 98.9 95.4 208.6 140.5 133.1 117.7 6.8 97.6 60.1 235.6 65.8 200.3 56.9 58.1 60.0 67.5 57.5 60.3 58.9 58.3 59.5 59.5 60.1 62.6 63.8 64.1 57.6 11.8 120.3 106.4 101.1 192.9 136.1 57.5 131.3 136.8 50.1 111.5 117.1 68.0 41.7 200.1 114.1 32.4 150.6 152.7 19.9 65.0 161.1 75.6 120.0 135.6 20.6 104.5 212.6 88.7 72.9 82.0 81.6 165.5 42.1 70.8 175.6 28.6 19.5 85.4 138.4 96.7 89.4 5.8 80.5 95.2 64.0 11.2 121.9 77.4 75.2 22.6 19.4 78.2 73.1 64.3 71.1 60.4 66.2 170.1 64.6 51.6 52.6 87.5 174.2 8.5 43.0 106.4 97.0 101.5 75.1 198.4 157.6 76.8 ARHGAP36 FLJ30058 ENSG00000147256 "Rho GTPase activating protein 36" Q6ZRI8 X 131058346-131089885 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 22 "adrenal gland: 105.4;brain: 144.3;pituitary gland: 176.9" "Cell type enhanced" "Detected in some" "Astrocytes: 1.0;Breast glandular cells: 2.7;Oligodendrocyte precursor cells: 1.0;Skeletal myocytes: 1.5" "Cancer enriched" "Detected in some" 21 "thyroid cancer: 62.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 161 "SH-SY5Y: 176.9" "Region enhanced" "Detected in many" "hypothalamus: 89.4" "Low region specificity" "Detected in many" "HPA002064, HPA076209" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane" Yes NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 37: Myocytes - Muscle contraction" Nucleoplasm "Vesicles, Plasma membrane" "HPA002064: AB_1078891, HPA076209: " "unprognostic (2.92e-2)" "unprognostic (7.71e-9)" "unprognostic (2.19e-1)" "unprognostic (8.15e-2)" "unprognostic (1.67e-1)" "unprognostic (1.78e-1)" "unprognostic (2.73e-1)" "unprognostic (1.40e-2)" "unprognostic (1.34e-2)" "unprognostic (2.31e-1)" 0.2 105.4 20.1 0.0 3.7 0.0 1.4 0.8 3.2 1.6 0.8 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 13.5 132.5 0.0 0.0 0.0 0.0 35.0 46.1 0.0 0.0 0.0 176.9 0.1 144.3 0.2 0.1 0.0 0.2 0.0 6.6 0.1 0.0 0.0 4.7 0.0 0.1 0.8 52.1 0.4 0.1 1.1 0.0 0.0 0.1 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 176.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.1 3.7 0.8 3.2 13.5 132.5 35.0 46.1 144.3 4.7 52.1 10.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 ARHGAP39 "CrGAP, KIAA1688, Vilse" ENSG00000147799 "Rho GTPase activating protein 39" Q9C0H5 8 144529179-144605816 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 21.8" "Cell type enhanced" "Detected in many" "Astrocytes: 34.3;Endometrial ciliated cells: 31.4;Excitatory neurons: 41.7;Inhibitory neurons: 33.1;Oligodendrocytes: 30.8;Respiratory ciliated cells: 27.6;Rod photoreceptor cells: 24.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044491 Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "Nucleoplasm, Microtubules, Cytokinetic bridge" "HPA044491: AB_10794775" "unprognostic (3.42e-2)" "unprognostic (2.65e-2)" "unprognostic (9.85e-2)" "unprognostic (4.17e-1)" "unprognostic (1.53e-1)" "unprognostic (2.49e-1)" "unprognostic (1.74e-7)" "unprognostic (1.89e-2)" "unprognostic (3.00e-1)" "unprognostic (2.02e-1)" "unprognostic (6.90e-3)" "unprognostic (1.53e-1)" "unprognostic (5.19e-2)" "unprognostic (1.26e-2)" "unprognostic (1.42e-1)" "unprognostic (1.27e-1)" "unprognostic (9.97e-2)" 1.6 3.9 4.3 0.8 5.2 0.0 3.4 2.3 9.4 4.9 1.2 4.5 1.7 2.8 0.8 5.0 8.2 0.7 1.9 8.5 2.3 4.9 1.6 2.7 0.3 8.4 5.9 2.6 5.2 1.3 9.9 0.7 5.5 4.2 0.6 3.1 3.5 1.4 0.7 5.2 2.7 0.5 4.7 1.3 2.0 21.8 3.5 0.7 7.5 0.1 0.1 1.9 3.1 9.5 8.3 8.1 3.8 5.8 0.7 0.6 7.2 2.1 0.7 2.6 1.6 5.2 4.8 0.8 5.4 0.8 2.7 7.0 1.8 2.0 0.5 0.0 7.2 0.1 5.8 3.4 1.3 0.0 0.8 0.5 3.2 3.3 1.4 1.3 0.8 0.4 7.7 0.0 1.1 13.4 4.6 0.0 4.0 3.4 11.4 4.3 3.0 3.2 2.1 4.1 10.9 7.7 6.2 2.1 3.8 1.4 9.0 1.2 2.0 1.9 0.1 6.6 4.5 0.0 0.1 0.3 3.3 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 5.2 2.3 9.4 8.5 2.3 8.4 5.9 5.5 4.7 3.5 9.5 0.8 3.2 2.3 34.3 0.6 3.7 0.6 1.9 2.2 7.2 5.0 3.3 1.6 0.0 2.8 3.7 20.9 0.6 0.1 7.5 0.0 2.4 3.9 31.4 2.8 1.1 0.0 0.0 41.7 2.5 0.9 1.2 1.1 6.0 0.0 6.0 0.7 1.4 0.5 3.3 33.1 4.2 4.1 0.0 0.4 3.1 2.1 0.2 5.4 1.0 0.0 3.6 0.0 15.6 30.8 1.4 7.9 8.2 0.0 1.0 3.3 1.5 27.6 24.5 6.6 2.5 2.1 8.5 11.2 2.1 3.0 0.5 0.3 3.1 5.2 0.7 ARMCX2 "ALEX2, GASP9, KIAA0512" ENSG00000184867 "Armadillo repeat containing X-linked 2" Q7L311 X 101655281-101659850 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 154.8" "Cell type enhanced" "Detected in many" "Sertoli cells: 59.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 47.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 164.1;NTERA-2: 117.2;SuSa: 90.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005761 Enhanced Approved Nucleoplasm,Mitochondria Yes No "Cluster 21: B-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria Nucleoplasm "HPA005761: AB_10600782" "unprognostic (1.33e-1)" "unprognostic (2.26e-2)" "unprognostic (4.25e-2)" "unprognostic (1.48e-1)" "unprognostic (9.59e-2)" "unprognostic (6.96e-2)" "unprognostic (5.00e-2)" "unprognostic (1.87e-1)" "unprognostic (7.17e-2)" "unprognostic (3.41e-2)" "prognostic favorable (3.45e-5)" "unprognostic (9.06e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.69e-4)" "unprognostic (1.12e-1)" "unprognostic (6.73e-2)" "unprognostic (1.25e-1)" 17.0 46.2 28.7 11.5 29.1 0.5 17.6 22.8 29.7 36.9 26.5 25.4 5.4 30.6 154.8 9.2 28.8 20.6 33.2 29.1 31.6 28.3 3.2 16.8 8.5 25.9 26.2 47.8 18.9 71.2 78.3 26.3 27.5 28.3 7.9 15.3 44.5 67.9 6.2 6.5 13.0 32.3 23.4 21.3 16.3 5.8 28.1 7.7 59.7 7.5 6.5 26.9 20.1 25.4 0.0 0.0 50.8 0.4 43.6 39.4 0.4 56.0 70.4 1.4 1.4 0.0 21.8 0.0 0.0 74.6 0.0 1.5 0.0 1.3 0.6 0.0 2.0 0.2 60.9 0.0 46.4 0.4 0.1 63.7 17.6 43.5 0.4 68.3 59.7 0.0 0.2 0.3 164.1 0.0 0.0 0.6 117.2 3.4 0.3 14.5 88.9 0.3 2.8 0.0 20.4 36.6 0.0 0.2 1.7 90.3 25.9 0.1 13.0 61.9 65.1 38.8 0.4 0.0 0.0 0.2 55.7 0.1 1.2 0.0 0.4 0.0 1.0 0.9 0.4 2.8 0.9 0.9 0.7 4.0 2.4 2.5 0.0 2.8 0.6 0.9 0.7 1.1 28.7 29.1 22.8 29.7 29.1 31.6 25.9 26.2 27.5 23.4 28.1 25.4 10.4 16.0 6.4 8.5 8.2 4.2 16.4 5.8 21.1 12.5 18.0 20.8 28.7 5.7 11.4 33.1 8.4 1.2 2.4 0.1 3.9 9.6 0.2 11.2 23.4 13.3 9.1 3.2 15.4 2.0 0.7 28.4 4.6 15.2 2.5 18.1 19.2 0.7 3.8 1.7 14.3 3.0 2.0 2.4 6.5 1.3 24.2 7.4 5.4 11.2 7.1 9.3 0.0 16.1 14.0 2.2 0.1 24.5 2.8 16.5 0.3 4.3 4.9 11.3 59.2 31.8 23.9 1.4 1.9 3.8 3.0 5.1 2.5 4.6 1.6 7.2 ASH2L "ASH2, ASH2L1, ASH2L2, Bre2" ENSG00000129691 "ASH2 like, histone lysine methyltransferase complex subunit" Q9UBL3 8 38105493-38144076 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 69.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 200.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042289 Approved Supported "Nucleoplasm,Plasma membrane" Yes No "Cluster 2: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 36: HEL - Hemostasis" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA042289: AB_10795608" "unprognostic (9.39e-2)" "unprognostic (5.58e-3)" "unprognostic (2.67e-3)" "unprognostic (5.40e-3)" "unprognostic (2.87e-1)" "unprognostic (2.66e-2)" "unprognostic (4.04e-1)" "unprognostic (9.15e-2)" "unprognostic (1.30e-1)" "unprognostic (1.12e-1)" "unprognostic (5.10e-2)" "unprognostic (9.73e-3)" "prognostic favorable (4.25e-4)" "unprognostic (9.95e-2)" "unprognostic (1.27e-1)" "unprognostic (7.69e-3)" "unprognostic (2.54e-1)" 28.9 18.9 19.7 17.9 20.3 31.6 21.4 19.2 21.5 19.9 14.7 22.5 18.2 22.0 17.1 23.8 20.1 17.4 21.3 20.2 17.4 23.3 23.6 18.5 27.9 16.7 16.1 26.2 17.7 24.8 12.0 22.1 16.7 19.9 22.3 21.7 20.6 21.0 32.4 20.4 18.3 24.2 16.5 18.9 22.1 41.3 19.0 33.6 21.1 27.7 28.3 18.5 16.1 18.1 45.6 23.3 39.8 39.8 26.3 34.0 49.8 44.1 45.7 53.5 47.0 24.9 21.1 51.4 38.2 37.1 27.2 27.5 49.0 24.8 50.4 20.3 22.4 200.3 22.9 51.7 39.4 32.0 41.3 28.6 22.9 25.0 27.7 28.1 43.9 48.0 138.2 40.0 53.7 26.1 91.9 40.7 51.7 39.3 15.6 38.2 42.9 23.4 28.9 33.1 18.3 32.4 33.5 22.5 38.4 37.1 27.4 40.4 33.5 35.3 35.0 50.4 37.6 37.8 48.7 44.9 35.2 44.7 49.7 39.9 23.0 55.9 16.8 26.8 18.1 19.6 18.8 20.0 27.7 19.2 19.3 18.4 19.2 26.1 25.8 15.8 21.3 21.6 19.7 20.3 19.2 21.5 20.2 17.4 16.7 16.1 16.7 16.5 19.0 18.1 11.1 12.8 15.8 18.3 14.3 6.9 9.3 13.3 10.8 12.9 9.6 8.0 18.1 8.6 15.9 12.9 10.4 37.0 15.9 11.5 7.9 21.2 10.8 12.7 13.2 14.0 10.8 62.1 19.7 28.7 37.2 17.3 8.6 10.8 19.6 38.2 12.8 11.9 24.2 6.7 21.4 11.6 12.2 17.2 5.7 13.0 23.3 17.0 23.2 15.9 29.2 17.8 19.6 17.6 16.5 21.3 8.9 20.7 8.4 6.2 12.8 17.1 18.0 15.5 13.1 14.6 20.7 69.6 33.9 11.6 6.8 30.9 11.9 37.3 10.9 7.4 ASRGL1 "ALP, ALP1, FLJ22316" ENSG00000162174 "Asparaginase and isoaspartyl peptidase 1" Q7L266 11 62337448-62393412 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 112.7;cervix: 121.7;testis: 100.5" "Cell type enhanced" "Detected in many" "Early spermatids: 372.5;Endometrial ciliated cells: 414.6;Glandular and luminal cells: 437.1;Late spermatids: 597.6;Proximal tubular cells: 214.1;Spermatocytes: 534.3" "Cancer enhanced" "Detected in all" "endometrial cancer: 53.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 277.9;eosinophil: 269.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 277.9" "Cell line enhanced" "Detected in many" "EFO-21: 85.2;HAP1: 83.9;SCLC-21H: 112.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029725, HPA055572, CAB070192" Enhanced Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes NA "Cluster 2: Granulocytes - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 44: Endometrium - Transcription" Microtubules "Nucleoplasm, Cytokinetic bridge" "CAB070192: AB_2665720, HPA029725: AB_10602328, HPA055572: AB_2682854" "unprognostic (1.14e-1)" "unprognostic (8.38e-3)" "prognostic favorable (6.14e-4)" "prognostic favorable (1.56e-5)" "unprognostic (5.35e-2)" "unprognostic (8.19e-2)" "prognostic unfavorable (9.46e-4)" "unprognostic (8.67e-2)" "unprognostic (1.85e-1)" "unprognostic (3.54e-2)" "unprognostic (2.71e-1)" "unprognostic (4.44e-1)" "prognostic favorable (4.32e-7)" "unprognostic (2.28e-2)" "unprognostic (1.53e-1)" "unprognostic (5.43e-3)" "unprognostic (1.40e-1)" 13.8 3.7 94.2 6.5 95.4 14.4 12.0 92.5 103.5 121.7 71.7 14.2 6.8 26.4 3.1 2.1 68.1 11.2 6.2 87.1 93.3 42.5 10.2 25.8 5.6 87.5 102.7 1.8 13.4 2.3 21.2 3.2 87.6 23.8 17.1 17.8 13.2 7.2 7.3 2.9 9.5 4.4 83.4 4.7 15.1 100.5 112.7 10.3 6.7 3.0 4.7 4.3 2.0 90.0 2.4 19.5 20.9 27.2 0.1 0.0 16.4 2.3 0.8 3.6 3.5 32.0 8.5 1.9 85.2 0.3 9.3 1.8 83.9 0.7 4.2 2.6 34.4 1.2 28.1 23.5 0.6 24.0 30.8 0.8 0.2 1.6 0.4 1.3 39.4 47.8 24.5 21.5 0.9 37.5 65.3 15.9 28.5 13.6 15.2 26.1 12.5 11.8 73.3 5.9 112.3 16.1 16.4 28.2 14.4 21.2 15.0 12.1 2.0 0.4 15.4 1.2 9.5 32.8 33.6 3.0 0.8 12.3 9.7 277.9 68.6 269.5 2.8 50.8 1.9 2.4 1.0 3.3 39.7 1.5 2.3 3.4 16.3 11.5 38.5 7.2 0.8 24.2 94.2 95.4 92.5 103.5 87.1 93.3 87.5 102.7 87.6 83.4 112.7 90.0 29.2 6.4 27.8 56.8 5.2 3.4 2.5 2.2 0.6 24.4 13.8 6.6 2.4 42.9 4.1 22.0 33.3 2.3 3.2 14.0 133.1 30.3 372.5 414.6 39.9 31.2 47.2 14.1 13.9 22.3 2.4 4.0 19.9 437.1 80.9 16.6 49.2 3.7 25.0 16.8 18.6 67.4 6.1 11.4 6.4 597.6 8.7 26.9 1.8 9.4 10.5 80.8 4.1 15.1 22.0 7.8 7.5 7.2 13.9 35.4 2.9 214.1 5.4 37.1 13.1 7.7 6.1 534.3 48.6 0.1 1.3 0.8 7.8 10.8 36.0 15.9 ATAD2 "ANCCA, CT137, DKFZp667N1320, MGC29843, MGC5254, PRO2000" ENSG00000156802 "ATPase family AAA domain containing 2" Q6PL18 8 123319850-123416350 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 28.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 79.1;Spermatocytes: 106.0;Spermatogonia: 82.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 294.4" "Low region specificity" "Detected in all" "HPA029424, CAB056158" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 33: Neutrophils - Chromatin organization" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB056158: AB_2665580, HPA029424: AB_10611680" "unprognostic (1.56e-1)" "unprognostic (4.55e-2)" "unprognostic (2.07e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.08e-1)" "unprognostic (4.44e-2)" "unprognostic (2.98e-2)" "unprognostic (2.74e-3)" "unprognostic (2.02e-3)" "unprognostic (5.62e-2)" "unprognostic (1.19e-2)" "unprognostic (4.98e-2)" "prognostic unfavorable (8.33e-15)" "unprognostic (1.15e-2)" "unprognostic (1.82e-1)" "unprognostic (4.84e-2)" "unprognostic (6.17e-2)" 2.9 3.4 3.8 7.7 3.6 26.5 6.8 2.6 3.9 12.8 2.0 5.3 5.0 4.3 3.8 6.8 3.4 3.2 5.8 3.2 4.5 1.4 9.9 4.1 14.4 2.9 3.8 7.0 3.3 1.9 3.9 4.8 2.6 10.3 6.9 1.4 4.3 4.7 9.3 6.8 5.2 4.1 2.8 4.9 4.7 18.9 5.1 28.3 3.9 3.2 12.8 4.8 3.9 2.8 103.7 39.6 55.0 19.0 9.7 12.3 24.3 79.2 27.2 66.8 73.9 30.1 43.8 67.2 23.6 25.2 26.5 48.3 74.2 25.6 106.1 94.3 39.0 121.2 41.0 61.4 3.8 44.6 57.4 4.1 3.8 63.6 21.0 14.3 20.7 38.6 57.7 66.4 50.4 107.1 129.5 32.8 10.0 77.8 38.4 66.5 65.6 36.4 23.8 46.7 70.2 30.5 114.4 294.4 20.8 22.1 60.2 41.2 13.0 50.4 69.3 40.2 96.6 21.2 40.7 60.8 32.9 72.9 40.4 5.3 0.8 3.3 1.6 0.8 2.2 2.6 2.3 2.7 1.4 1.5 1.5 1.7 0.2 2.5 1.9 0.1 4.6 1.0 3.8 3.6 2.6 3.9 3.2 4.5 2.9 3.8 2.6 2.8 5.1 2.8 4.8 6.4 11.0 9.4 18.5 15.8 27.9 9.1 14.2 2.8 17.3 21.2 27.3 2.8 10.2 3.7 4.2 14.9 15.3 9.0 1.9 3.5 54.9 7.9 17.3 9.6 1.2 79.1 25.6 2.2 26.2 17.1 13.3 17.5 14.5 37.9 7.1 16.3 11.2 1.7 16.4 13.1 4.1 8.2 6.9 24.4 7.5 11.7 1.8 14.0 6.3 6.3 17.5 11.6 2.8 3.5 4.3 13.9 34.0 20.7 3.1 1.0 5.4 1.9 0.0 9.5 17.5 106.0 82.4 23.7 12.1 13.5 22.8 3.7 14.6 24.5 ATAD5 "C17orf41, ELG1, FLJ12735, FRAG1" ENSG00000176208 "ATPase family AAA domain containing 5" Q96QE3 17 30831966-30895869 "Predicted intracellular proteins" "DNA damage" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 59.3;Spermatocytes: 73.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA066823 Approved "Nucleoplasm,Cytokinetic bridge,Centriolar satellite,Cytosol" "Intracellular and membrane" Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cytokinetic bridge, Centriolar satellite, Cytosol" "HPA066823: " "unprognostic (3.12e-1)" "unprognostic (7.36e-2)" "unprognostic (1.12e-2)" "unprognostic (1.36e-3)" "unprognostic (3.33e-1)" "unprognostic (1.05e-2)" "unprognostic (1.28e-4)" "unprognostic (1.77e-1)" "unprognostic (1.79e-3)" "unprognostic (7.24e-2)" "unprognostic (2.78e-1)" "unprognostic (3.19e-3)" "unprognostic (6.30e-10)" "unprognostic (3.10e-2)" "unprognostic (1.19e-1)" "unprognostic (3.42e-1)" "unprognostic (1.38e-1)" 0.7 0.4 0.3 2.1 0.2 12.3 1.2 2.6 0.5 0.8 0.1 1.2 1.4 1.0 0.4 1.3 0.7 0.5 0.4 0.3 0.2 0.4 0.5 0.8 3.6 0.2 0.1 0.9 0.5 0.3 0.5 1.4 0.3 0.6 1.6 2.5 0.7 0.4 0.4 2.5 1.4 0.6 0.1 1.4 1.1 2.0 0.3 5.3 0.6 0.1 2.9 0.6 0.9 0.6 7.2 6.0 14.0 13.3 0.3 1.4 5.5 6.3 3.2 6.9 9.8 6.6 5.1 19.5 5.9 2.9 4.7 13.0 9.1 4.7 12.4 4.4 7.9 11.7 8.0 4.6 0.2 23.1 9.2 0.6 0.6 10.1 3.5 1.4 3.6 18.7 18.7 15.9 4.6 4.2 26.1 11.5 8.2 5.3 2.9 17.6 26.4 9.3 1.8 7.6 8.1 7.2 7.0 4.0 3.7 7.6 7.6 10.2 2.8 8.3 11.3 12.0 11.4 5.2 5.9 24.0 3.6 10.7 8.4 0.4 0.2 0.3 0.3 0.3 0.2 0.3 0.1 0.2 0.1 0.4 0.2 0.2 0.6 0.6 0.1 0.5 0.3 0.1 0.3 0.2 2.6 0.5 0.3 0.2 0.2 0.1 0.3 0.1 0.3 0.6 4.3 3.2 4.1 6.8 9.9 4.7 3.1 2.6 3.4 19.3 4.7 5.1 2.7 0.0 2.6 3.7 0.0 21.7 10.7 6.6 0.0 4.1 13.9 4.4 8.5 5.4 0.0 59.3 20.4 2.9 21.1 5.4 9.7 5.1 3.8 32.6 2.9 0.7 8.7 11.8 17.4 8.6 2.0 2.8 7.4 7.8 3.7 5.7 7.2 11.2 10.0 2.9 12.3 16.6 14.9 4.0 2.4 2.2 24.4 2.4 2.3 0.5 2.7 21.3 0.0 7.4 6.5 73.3 34.5 9.3 4.5 7.9 10.5 8.4 13.0 2.3 ATF3 ENSG00000162772 "Activating transcription factor 3" P18847 1 212565334-212620777 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 1462.0;Endometrial ciliated cells: 1049.4;Glandular and luminal cells: 1429.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 6.4;intermediate monocyte: 4.0;myeloid DC: 1.6;non-classical monocyte: 6.3" "Group enriched" "Detected in many" 15 "dendritic cells: 1.6;granulocytes: 6.4;monocytes: 6.3" "Cell line enhanced" "Detected in many" "BEWO: 131.5;HDLM-2: 100.4;SuSa: 155.0" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 9.3" HPA001562 Approved Supported Nucleoplasm,Nucleoli Yes Yes "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nucleoli" "HPA001562: AB_1078233" "unprognostic (2.66e-2)" "unprognostic (1.52e-2)" "unprognostic (2.80e-1)" "unprognostic (4.27e-3)" "unprognostic (3.29e-1)" "unprognostic (1.46e-1)" "unprognostic (1.31e-1)" "unprognostic (1.73e-1)" "unprognostic (9.31e-2)" "unprognostic (8.65e-3)" "unprognostic (8.75e-2)" "unprognostic (1.52e-1)" "unprognostic (6.97e-2)" "unprognostic (3.31e-2)" "unprognostic (1.10e-1)" "unprognostic (2.04e-2)" "unprognostic (2.08e-2)" 176.1 82.8 14.2 63.3 17.7 45.3 97.6 16.5 18.7 106.2 17.1 66.6 21.0 108.6 9.3 128.4 122.6 135.0 113.7 14.4 20.2 98.1 139.9 116.0 20.8 21.1 16.7 40.2 67.2 48.8 45.0 66.3 17.2 116.3 60.0 16.2 33.1 24.1 30.7 154.9 45.6 313.0 15.4 24.4 104.8 3.9 18.8 84.5 181.1 30.0 3.1 281.2 55.2 25.0 21.1 1.2 40.7 8.7 3.9 10.4 131.5 14.7 11.9 12.5 29.8 27.7 15.5 0.4 6.5 0.9 68.0 11.6 24.6 4.0 20.5 100.4 24.6 1.6 11.6 10.0 72.9 9.0 22.7 18.3 65.3 34.9 80.4 2.4 2.6 23.9 10.0 77.0 1.9 2.8 27.5 5.9 29.2 11.5 9.2 8.1 27.1 18.4 1.8 3.0 18.3 18.4 19.1 34.2 59.0 155.0 19.9 6.5 2.4 3.6 19.5 12.3 6.7 60.4 27.9 7.4 11.9 4.8 10.8 6.4 0.7 0.0 0.3 4.0 0.3 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.2 0.0 6.3 0.8 0.0 0.7 14.2 17.7 16.5 18.7 14.4 20.2 21.1 16.7 17.2 15.4 18.8 25.0 568.2 423.1 146.5 1.6 55.3 202.8 866.2 236.1 1462.0 4.4 753.9 510.9 689.3 92.9 136.0 55.2 0.0 178.9 100.3 611.7 1.9 186.2 3.7 1049.4 318.2 176.2 889.6 2.7 2.6 122.7 330.8 452.6 966.9 1429.3 78.6 5.6 30.7 25.8 103.7 1.7 2.4 758.4 114.0 29.8 282.8 2.8 17.4 351.8 174.3 3.7 32.3 39.9 0.0 1.5 10.8 185.7 484.8 1.2 161.0 457.5 421.3 3.3 133.2 5.3 98.6 279.4 573.7 2.2 3.1 474.6 202.7 420.6 97.1 5.8 349.6 263.6 ATP6V1D "ATP6M, VATD, VMA8" ENSG00000100554 "ATPase H+ transporting V1 subunit D" Q9Y5K8 14 67294371-67360265 "Metabolic proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 365.9;Proximal tubular cells: 365.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031515, HPA057316" Enhanced Approved Nucleoplasm Yes No 19000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA031515: AB_10600785, HPA057316: AB_2683409" "unprognostic (1.10e-1)" "unprognostic (7.35e-2)" "unprognostic (1.59e-1)" "unprognostic (7.10e-3)" "unprognostic (1.52e-1)" "unprognostic (7.64e-2)" "unprognostic (7.78e-3)" "unprognostic (1.19e-1)" "unprognostic (2.32e-1)" "unprognostic (3.05e-2)" "unprognostic (1.13e-2)" "unprognostic (3.08e-2)" "prognostic favorable (7.60e-13)" "unprognostic (2.78e-1)" "unprognostic (3.18e-2)" "unprognostic (1.41e-2)" "unprognostic (1.44e-2)" 43.4 116.2 98.0 32.2 103.2 28.8 43.8 91.8 119.7 40.3 101.8 52.9 40.4 34.3 72.5 96.7 48.1 38.7 136.6 107.2 103.5 129.8 51.7 37.5 33.3 96.1 98.4 26.1 36.2 88.8 65.8 43.4 106.7 55.7 57.5 78.0 45.1 49.8 78.5 40.4 41.7 46.4 95.1 24.3 43.8 42.5 99.7 52.4 89.5 108.5 46.3 54.5 54.1 99.6 242.5 64.7 96.2 62.4 80.2 82.8 73.5 199.1 109.4 145.8 109.1 76.2 85.2 24.8 73.9 155.1 105.3 89.2 72.6 117.9 195.7 82.5 50.8 23.4 74.5 51.0 144.0 24.9 64.8 65.1 77.7 105.4 73.1 131.4 97.6 58.6 50.2 55.3 206.6 78.5 66.5 46.2 60.7 104.6 83.3 48.8 84.2 32.8 171.2 104.3 120.2 49.8 122.9 65.4 145.6 96.2 98.3 53.4 123.8 162.4 121.6 77.6 120.1 55.8 46.1 33.4 150.2 44.1 96.1 106.7 77.5 92.8 48.5 78.8 40.8 39.9 53.2 52.7 83.4 42.0 41.6 41.7 94.0 48.9 83.5 73.9 78.8 65.0 98.0 103.2 91.8 119.7 107.2 103.5 96.1 98.4 106.7 95.1 99.7 99.6 31.3 54.5 63.0 13.4 27.6 96.2 66.6 112.3 26.2 60.0 44.8 41.8 160.8 55.8 85.0 82.8 54.2 92.3 51.4 91.6 365.9 125.9 190.3 120.8 44.1 40.7 54.4 78.1 22.7 48.9 85.5 51.5 42.3 71.8 41.2 39.8 27.5 45.8 132.0 87.5 21.0 49.4 175.0 44.6 61.0 97.9 32.9 62.2 80.0 6.5 58.5 89.4 47.4 9.5 22.1 121.5 78.7 50.8 21.3 65.9 80.9 365.5 184.1 94.2 13.1 44.5 64.1 100.1 61.5 78.4 138.4 205.9 40.8 71.6 40.6 113.8 ATXN1 "ATX1, D6S504E, SCA1" ENSG00000124788 "Ataxin 1" P54253 6 16299112-16761491 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor, RNA-binding" "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 582.5;Inhibitory neurons: 519.0;Oligodendrocyte precursor cells: 318.2;Oligodendrocytes: 466.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 14.4" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-266/70: 30.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008335, HPA070756" Approved Supported Nucleoplasm,Nucleoli,Cytosol Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Nucleoli, Cytosol" "HPA008335: AB_1845129, HPA070756: AB_2686306" "unprognostic (1.01e-1)" "unprognostic (4.77e-2)" "unprognostic (1.23e-1)" "unprognostic (5.64e-3)" "unprognostic (4.54e-1)" "unprognostic (1.95e-2)" "unprognostic (7.74e-2)" "unprognostic (4.51e-2)" "unprognostic (4.06e-1)" "unprognostic (1.11e-2)" "unprognostic (3.87e-2)" "unprognostic (2.69e-2)" "unprognostic (1.41e-3)" "unprognostic (1.67e-3)" "unprognostic (2.33e-1)" "unprognostic (1.06e-1)" "unprognostic (3.29e-3)" 4.1 4.0 3.2 5.9 5.3 2.6 4.1 0.0 14.4 8.4 0.0 8.8 3.8 10.9 4.3 5.0 6.2 5.7 5.8 8.4 0.0 4.1 4.7 6.9 4.2 0.0 1.3 5.4 4.8 5.5 6.5 4.9 0.0 7.4 3.8 13.9 4.6 6.2 14.6 5.7 4.8 7.5 0.0 5.7 5.3 3.0 3.9 2.6 6.1 14.8 3.1 6.7 6.6 0.8 4.5 2.6 0.9 0.0 4.4 5.9 5.8 4.8 11.2 2.9 3.3 2.8 2.8 0.2 6.3 9.3 3.7 4.2 0.3 3.0 4.2 2.6 4.7 0.7 4.4 9.0 7.0 4.2 7.0 4.6 5.7 6.1 5.1 11.2 5.9 0.9 0.0 5.3 2.4 2.3 0.3 4.8 0.9 1.4 4.3 0.3 5.8 4.0 4.0 7.6 0.3 2.5 4.4 5.5 9.1 8.4 3.6 7.2 9.1 4.0 6.1 4.8 4.4 30.7 19.2 0.2 2.6 4.3 10.0 0.2 0.5 0.1 0.7 0.4 0.5 0.1 0.5 0.7 0.2 0.0 0.0 0.4 1.3 0.0 0.2 0.1 0.4 0.3 3.2 5.3 0.0 14.4 8.4 0.0 0.0 1.3 0.0 0.0 3.9 0.8 16.0 48.1 25.9 206.3 20.7 91.4 72.2 22.8 48.9 39.8 20.7 14.4 35.9 25.8 26.0 11.0 100.1 0.6 48.4 23.6 7.9 16.7 4.3 80.5 144.4 21.7 1.2 5.7 582.5 8.5 4.0 32.9 22.4 75.8 38.7 67.4 17.2 25.2 22.4 38.7 519.0 16.5 2.0 39.6 79.1 3.3 10.5 41.7 32.0 217.4 42.3 24.1 33.0 318.2 466.8 32.3 16.3 28.2 82.6 56.6 13.9 8.8 33.2 99.9 52.6 19.0 41.6 1.0 6.9 60.9 48.7 0.4 61.5 6.4 7.7 63.8 AURKA "AIK, ARK1, AurA, BTAK, PPP1R47, STK15, STK6, STK7" ENSG00000087586 "Aurora kinase A" O14965 20 56369389-56392337 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 22.1;testis: 30.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 81.6;Extravillous trophoblasts: 67.1;granulocytes: 54.1;Spermatocytes: 168.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB001454, HPA002636" Enhanced Approved "Nucleoplasm,Mitotic spindle,Centrosome,Cytosol" Yes Yes "Cluster 7: Monocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Centrosome" "Mitotic spindle, Cytosol" "CAB001454: AB_563420, HPA002636: AB_1845217" "unprognostic (7.73e-2)" "unprognostic (2.46e-2)" "unprognostic (2.76e-2)" "prognostic unfavorable (9.40e-5)" "unprognostic (1.92e-1)" "unprognostic (2.11e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (4.69e-3)" "unprognostic (2.42e-1)" "unprognostic (6.88e-2)" "prognostic unfavorable (6.13e-4)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.47e-8)" "unprognostic (1.67e-1)" "unprognostic (6.83e-2)" "unprognostic (9.00e-2)" "unprognostic (5.14e-2)" 1.3 2.3 1.3 10.4 1.6 15.3 2.2 2.4 1.4 1.4 0.6 10.8 11.7 1.5 0.8 7.5 1.2 2.0 5.3 0.8 1.0 2.3 5.0 2.2 20.9 1.7 1.2 8.4 2.0 1.8 0.6 8.1 1.4 1.1 12.9 3.0 1.9 1.3 8.7 3.5 9.3 4.9 1.3 5.2 4.9 30.8 1.6 20.2 1.4 8.2 22.1 2.9 2.6 1.3 179.9 127.2 84.5 61.2 4.9 10.8 106.3 145.2 66.8 339.7 142.9 361.4 124.8 58.4 96.2 59.2 176.2 142.2 152.4 96.4 360.0 52.4 57.5 102.6 128.9 229.8 2.8 140.4 140.4 5.1 10.1 117.3 104.5 26.7 80.7 93.2 121.8 45.3 146.9 182.1 85.3 108.9 78.3 145.6 129.8 62.9 163.4 65.9 56.0 46.8 73.9 39.6 200.5 228.8 94.2 77.3 137.9 86.1 47.1 149.7 145.3 83.0 208.6 62.3 78.9 100.5 80.5 80.9 127.0 0.2 3.5 4.3 1.2 5.9 1.8 2.5 2.0 1.1 3.7 0.8 0.9 0.9 2.3 1.4 3.4 0.8 4.7 1.7 1.3 1.6 2.4 1.4 0.8 1.0 1.7 1.2 1.4 1.3 1.6 1.3 2.5 0.0 2.8 0.3 7.4 1.1 1.2 5.6 0.6 1.0 4.3 6.2 5.6 1.5 2.3 3.7 2.1 34.5 8.3 8.3 1.9 4.0 33.9 2.0 2.3 3.1 6.0 81.6 1.1 4.9 67.1 7.0 13.7 3.4 54.1 12.3 3.6 2.6 17.5 1.7 1.5 10.8 2.0 3.5 7.6 16.3 1.5 11.7 0.0 1.0 12.0 3.7 3.1 1.0 2.0 5.2 2.8 0.4 10.1 2.0 5.1 4.2 1.5 2.7 6.6 2.2 7.7 168.2 30.8 8.3 1.1 8.2 8.0 8.7 15.5 1.5 AURKB "Aik2, AIM-1, ARK2, AurB, IPL1, PPP1R48, STK12, STK5" ENSG00000178999 "Aurora kinase B" Q96GD4 17 8204733-8210600 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 44.1;lymphoid tissue: 60.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 40.5;Erythroid cells: 59.3;Extravillous trophoblasts: 89.1;Granulosa cells: 24.7;Hofbauer cells: 29.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "T-reg: 7.9" "Group enriched" "Detected in many" 6 "B-cells: 2.5;T-cells: 7.9" "Low cell line specificity" "Detected in many" "Group enriched" "Detected in some" 5 "basal ganglia: 1.3;white matter: 4.0" "Low region specificity" "Detected in all" "CAB005862, HPA037708" Enhanced Enhanced Nucleoplasm,Midbody Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Midbody "CAB005862: AB_449204, HPA037708: AB_2675623" "unprognostic (4.76e-2)" "unprognostic (3.61e-3)" "unprognostic (2.25e-1)" "unprognostic (3.14e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (1.99e-3)" "unprognostic (9.41e-3)" "unprognostic (3.47e-2)" "unprognostic (4.61e-3)" "unprognostic (1.01e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.77e-2)" "unprognostic (2.93e-1)" "unprognostic (6.76e-2)" "unprognostic (3.77e-1)" 1.1 1.2 0.1 14.2 0.2 44.1 1.7 0.2 0.2 3.0 0.1 11.1 12.1 1.6 0.4 18.6 0.6 1.5 0.7 0.1 0.2 0.9 2.0 2.5 36.7 0.1 0.3 0.5 0.6 0.3 0.2 8.2 0.3 0.8 11.0 0.0 2.7 0.3 5.5 9.3 11.6 3.2 0.0 12.0 4.6 1.2 0.4 60.1 0.6 0.0 36.6 3.5 5.9 0.2 196.5 130.9 191.1 93.0 4.2 6.5 73.4 91.7 49.5 186.2 170.6 171.5 57.4 193.3 46.2 37.0 77.0 139.8 140.1 62.6 153.7 84.9 231.3 115.7 78.3 146.1 0.7 62.2 109.2 3.5 2.9 109.4 67.7 18.5 86.5 123.6 73.3 73.4 82.9 92.9 225.1 87.4 119.6 63.9 57.6 149.8 176.1 80.5 41.2 38.2 41.2 59.1 81.7 36.5 61.2 56.5 63.5 41.4 33.9 74.3 75.6 67.6 243.3 53.2 37.7 147.9 35.7 92.9 153.4 0.0 0.4 0.6 0.5 0.3 0.1 1.1 1.3 2.1 0.5 2.5 0.1 0.7 0.9 0.3 0.2 0.2 7.9 0.9 0.1 0.2 0.2 0.2 0.1 0.2 0.1 0.3 0.3 0.0 0.4 0.2 0.3 0.0 0.5 0.0 7.6 4.5 1.8 6.1 0.6 0.0 1.8 2.2 1.4 0.0 2.6 0.0 0.0 40.5 1.8 13.2 0.0 0.4 0.1 0.5 1.6 3.1 0.0 59.3 0.0 0.0 89.1 5.7 6.1 2.1 4.5 24.7 6.1 0.7 29.4 0.0 0.0 10.8 0.0 5.7 7.3 0.2 0.6 5.1 1.8 0.0 0.9 0.0 3.1 0.0 0.1 0.3 2.8 0.0 15.4 1.2 1.5 0.1 0.2 0.0 0.0 0.1 4.8 1.6 7.2 11.8 2.4 9.0 4.3 1.0 22.0 2.8 AUTS2 "FBRSL2, KIAA0442" ENSG00000158321 "Activator of transcription and developmental regulator AUTS2" Q8WXX7 7 69598296-70793506 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Autism, Autism spectrum disorder, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.4" "Cell type enhanced" "Detected in many" "Astrocytes: 598.7;Excitatory neurons: 871.5;Inhibitory neurons: 1405.7;Microglial cells: 583.7;Oligodendrocytes: 1231.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 8.1;naive B-cell: 9.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 82.8;REH: 84.1;SCLC-21H: 112.5;T-47d: 80.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000390 Approved Approved Nucleoplasm,Cytosol Yes No "Cluster 21: B-cells - Adaptive immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "HPA000390: AB_1845218" "unprognostic (8.73e-3)" "unprognostic (2.24e-1)" "unprognostic (4.62e-2)" "unprognostic (8.78e-2)" "unprognostic (2.44e-2)" "unprognostic (1.04e-1)" "unprognostic (1.65e-2)" "unprognostic (2.68e-2)" "unprognostic (1.07e-3)" "unprognostic (3.33e-2)" "unprognostic (3.52e-2)" "unprognostic (8.46e-2)" "unprognostic (3.29e-3)" "unprognostic (1.76e-2)" "unprognostic (2.47e-1)" "unprognostic (3.04e-1)" "unprognostic (7.33e-2)" 8.7 5.2 50.4 9.1 41.1 8.5 17.2 10.6 19.0 7.9 0.0 11.3 6.8 7.4 6.2 11.5 7.0 13.3 5.5 21.8 32.0 13.9 20.2 10.8 4.8 40.6 25.9 14.6 5.7 11.3 9.7 4.1 23.0 11.3 10.0 11.0 48.2 5.7 15.2 20.5 15.6 7.5 14.0 6.5 10.5 7.9 37.3 10.7 5.8 5.2 6.3 10.5 10.5 8.7 0.3 7.5 82.8 4.3 5.4 3.2 0.9 5.2 0.0 0.4 0.5 29.1 0.3 13.0 1.9 5.0 0.5 27.1 10.0 11.5 2.3 60.5 22.4 6.2 7.8 0.3 2.4 0.1 0.4 8.6 15.2 12.5 3.1 3.0 0.0 13.5 0.6 6.5 7.2 4.8 1.2 2.4 59.0 18.9 0.1 84.1 40.0 39.8 0.0 12.5 112.5 61.3 5.3 9.2 0.2 35.4 80.0 0.1 0.0 0.3 27.1 8.8 52.6 0.2 0.2 43.1 0.1 0.2 0.2 1.0 0.2 0.1 1.4 0.1 1.9 8.1 0.9 1.4 0.6 9.4 0.1 0.8 0.4 1.5 0.1 2.8 0.2 0.6 50.4 41.1 10.6 19.0 21.8 32.0 40.6 25.9 23.0 14.0 37.3 8.7 13.7 19.2 38.2 598.7 19.9 28.6 21.1 25.0 34.7 37.2 72.9 41.5 20.8 11.5 22.2 9.2 16.7 1.2 103.2 23.5 5.9 13.1 31.8 11.5 36.0 15.9 28.9 5.2 871.5 1.3 0.1 19.3 4.1 11.0 0.0 44.4 12.1 28.8 0.8 63.9 1405.7 23.4 38.7 2.6 17.1 27.7 15.8 5.5 17.8 583.7 0.8 11.2 25.7 292.0 1231.2 3.9 15.3 14.7 37.7 32.6 15.3 12.4 20.3 20.7 26.3 13.7 17.2 10.1 16.9 20.3 16.1 1.4 35.5 10.4 25.3 26.6 B3GNT7 beta3GnT7 ENSG00000156966 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7" Q8NFL0 2 231395710-231401164 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 71.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 272.8;Intestinal goblet cells: 145.2;Paneth cells: 126.4;Undifferentiated cells: 354.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 32.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CAPAN-2: 19.5;HEL: 15.6;THP-1: 14.0;WM-115: 23.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA013881, HPA035625, HPA035626" Enhanced Approved "Golgi apparatus,Mitotic spindle,Cytosol" "Intracellular and membrane" Yes NA 3600000 "Cluster 40: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "Mitotic spindle, Cytosol" "HPA013881: , HPA035625: AB_10601118, HPA035626: AB_2674707" "unprognostic (2.21e-1)" "unprognostic (1.15e-1)" "unprognostic (4.57e-3)" "unprognostic (1.46e-2)" "unprognostic (1.28e-2)" "unprognostic (2.69e-1)" "unprognostic (1.36e-1)" "unprognostic (2.31e-2)" "unprognostic (6.18e-2)" "unprognostic (5.82e-2)" "unprognostic (2.17e-2)" "unprognostic (7.77e-2)" "unprognostic (4.27e-3)" "unprognostic (6.96e-2)" "unprognostic (1.18e-1)" "prognostic favorable (6.00e-4)" "unprognostic (3.57e-1)" 3.1 12.9 5.9 2.8 5.1 14.2 3.8 4.0 5.8 2.5 4.6 56.2 25.2 1.9 6.8 2.9 4.6 14.0 4.7 5.6 6.5 2.2 1.2 15.3 1.6 6.0 7.0 16.7 25.4 14.3 8.8 5.4 5.3 3.2 71.2 2.1 7.5 4.4 0.4 5.0 28.4 2.3 4.3 5.1 35.6 1.3 7.3 2.4 8.4 0.3 1.5 3.7 0.6 5.4 0.7 2.8 0.3 0.6 0.1 0.2 1.0 0.2 1.1 0.1 0.1 1.4 19.5 2.2 5.8 0.3 0.2 5.1 0.2 0.0 0.1 0.3 0.5 15.6 0.5 0.9 0.1 0.1 0.8 0.1 1.4 0.2 0.3 1.1 0.2 0.4 0.5 0.4 0.1 0.9 0.2 0.7 6.3 7.7 3.3 0.3 0.1 0.4 0.6 1.7 0.5 0.8 0.3 1.7 0.7 6.9 0.6 14.0 0.2 0.4 0.4 0.2 0.2 2.3 0.9 0.7 0.3 0.2 23.7 0.7 0.1 0.7 2.9 0.5 0.5 9.9 0.1 0.4 6.5 7.0 0.1 0.7 0.2 32.1 0.6 3.1 0.2 1.0 5.9 5.1 4.0 5.8 5.6 6.5 6.0 7.0 5.3 4.3 7.3 5.4 0.9 41.7 30.2 0.3 8.7 2.3 1.7 8.7 0.0 0.4 5.2 2.5 1.1 95.8 29.7 1.8 2.1 0.6 61.7 272.8 0.0 16.1 0.4 13.3 2.2 4.7 103.0 0.4 0.5 84.3 64.9 2.3 51.5 18.5 9.5 17.3 3.3 0.2 11.2 0.0 0.4 145.2 18.3 10.1 38.6 1.2 1.5 9.7 3.6 0.0 2.9 0.5 10.3 55.3 0.2 69.8 126.4 8.2 5.5 11.6 93.2 0.4 82.2 1.8 0.0 0.5 2.3 0.9 1.4 0.0 2.7 2.1 10.0 0.4 354.6 16.2 BBS1 FLJ23590 ENSG00000174483 "Bardet-Biedl syndrome 1" Q8NFJ9 11 66510606-66533613 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Olfaction, Protein transport, Sensory transduction, Transport, Vision" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Mental retardation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 19.9;Excitatory neurons: 28.5;Inhibitory neurons: 28.4;Microglial cells: 14.0;Oligodendrocyte precursor cells: 13.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" HPA058283 Uncertain Uncertain Midbody Yes NA "Cluster 27: Non-specific - Gene expression" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Midbody "HPA058283: AB_2683667" "unprognostic (1.06e-1)" "unprognostic (1.05e-1)" "unprognostic (1.73e-1)" "unprognostic (1.14e-1)" "unprognostic (1.56e-1)" "unprognostic (1.08e-3)" "unprognostic (1.40e-2)" "unprognostic (6.68e-2)" "unprognostic (1.72e-2)" "unprognostic (2.76e-1)" "unprognostic (1.19e-3)" "unprognostic (2.61e-2)" "unprognostic (6.05e-2)" "unprognostic (3.04e-1)" "unprognostic (2.20e-1)" "unprognostic (2.38e-1)" "unprognostic (4.87e-4)" 10.5 15.2 11.5 4.9 13.0 2.9 11.9 10.8 17.8 18.9 13.9 18.0 6.5 20.7 17.7 9.0 28.0 12.6 10.1 11.6 12.7 24.2 7.0 10.4 5.1 10.2 13.5 27.5 13.5 38.0 17.9 8.2 10.1 15.8 7.3 21.4 16.8 22.0 8.1 9.6 9.4 14.1 10.5 6.0 13.8 10.5 13.3 8.0 27.1 8.2 5.0 15.4 10.9 10.7 5.7 6.0 13.7 5.4 24.9 17.2 6.3 4.8 9.6 6.3 6.0 9.5 10.1 0.8 10.0 11.5 5.6 10.6 10.1 10.6 6.8 5.2 5.8 2.5 8.9 5.3 11.7 4.7 1.8 17.7 9.7 9.7 7.1 17.8 8.9 8.5 5.5 4.3 7.8 5.1 3.7 4.1 10.4 18.0 10.5 9.2 9.0 7.4 19.3 6.4 14.0 9.3 8.1 8.7 18.6 6.6 18.7 2.5 8.7 5.0 5.7 6.0 1.6 3.1 1.5 1.4 16.3 1.3 5.4 0.0 1.5 0.2 1.8 1.6 2.6 2.2 2.5 2.0 1.2 1.1 1.7 2.2 0.9 3.1 3.0 0.5 0.8 1.9 11.5 13.0 10.8 17.8 11.6 12.7 10.2 13.5 10.1 10.5 13.3 10.7 0.5 0.0 2.2 19.9 2.5 0.5 1.3 1.6 0.6 3.9 0.9 1.0 0.5 1.5 1.1 0.0 8.4 1.6 0.5 0.6 0.0 0.8 4.1 2.3 1.8 1.3 1.2 3.0 28.5 0.4 0.6 3.1 7.1 0.9 0.0 2.9 0.7 0.3 0.6 0.0 28.4 0.7 2.0 0.9 0.7 2.6 0.9 0.5 0.0 14.0 0.8 1.7 1.0 13.6 9.0 0.4 0.5 1.5 2.5 0.8 0.4 1.7 9.2 10.8 0.0 1.5 1.6 4.9 2.6 2.2 1.0 1.0 1.4 2.0 0.9 0.9 BCKDHB ENSG00000083123 "Branched chain keto acid dehydrogenase E1 subunit beta" P21953 6 80106647-80346270 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Maple syrup urine disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 78.4" "Cell type enhanced" "Detected in all" "Astrocytes: 296.5;Early spermatids: 110.9;Inhibitory neurons: 94.9;Oligodendrocyte precursor cells: 98.5;Oligodendrocytes: 101.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031580, HPA031956" Approved Supported Nucleoplasm,Nucleoli,Mitochondria "Intracellular and membrane" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria "Nucleoplasm, Nucleoli" "HPA031580: AB_10696054, HPA031956: " "unprognostic (4.23e-1)" "unprognostic (1.61e-1)" "unprognostic (9.50e-3)" "unprognostic (9.37e-3)" "unprognostic (1.66e-1)" "unprognostic (6.03e-2)" "unprognostic (6.84e-3)" "unprognostic (2.30e-2)" "unprognostic (1.94e-1)" "unprognostic (7.32e-3)" "unprognostic (2.67e-1)" "unprognostic (4.65e-2)" "prognostic favorable (5.54e-9)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (8.02e-2)" "unprognostic (1.49e-2)" 19.7 10.7 7.3 7.6 8.3 8.2 22.3 11.5 7.8 11.7 11.6 22.5 11.5 9.2 7.1 10.3 11.5 7.8 18.8 8.8 7.0 31.8 78.4 7.3 8.8 10.7 9.2 14.6 12.9 19.7 7.2 4.8 13.1 15.9 20.7 7.9 26.6 11.3 10.9 8.5 12.4 9.4 11.8 6.3 17.6 13.1 8.7 9.1 15.5 15.3 9.1 11.2 7.6 16.0 13.8 5.1 18.8 25.3 18.6 16.1 14.9 9.7 19.8 15.4 21.0 8.3 18.5 38.9 10.1 23.1 18.0 13.6 10.6 12.7 21.5 48.8 15.6 19.4 12.6 11.3 20.7 27.7 8.3 15.6 12.8 10.7 13.3 13.8 18.6 29.8 16.6 33.8 35.0 7.6 10.3 16.3 14.0 30.1 6.5 25.5 58.3 33.8 43.2 20.7 12.6 17.8 16.2 13.4 9.9 20.6 17.3 21.1 8.0 9.2 6.3 8.5 13.0 24.0 25.2 12.9 11.3 20.4 14.2 3.4 4.2 1.0 10.1 5.1 13.3 10.6 8.3 8.5 8.3 12.7 11.0 11.6 0.8 17.4 5.9 12.9 20.3 6.1 7.3 8.3 11.5 7.8 8.8 7.0 10.7 9.2 13.1 11.8 8.7 16.0 8.4 9.6 21.0 296.5 11.5 8.5 12.5 21.1 15.9 7.8 19.6 14.7 29.3 8.6 18.0 5.5 2.1 17.0 9.1 17.5 27.4 8.2 110.9 8.3 10.3 8.0 12.0 10.3 72.0 10.4 8.3 13.7 15.3 17.6 16.5 19.2 11.0 66.5 12.2 3.3 94.9 31.3 10.2 9.1 9.0 13.7 8.7 5.4 16.0 59.0 7.3 15.5 10.3 98.5 101.7 5.4 10.4 8.6 8.4 6.2 11.5 33.1 13.5 8.7 6.6 11.1 9.4 15.2 5.6 20.1 12.4 10.4 9.9 15.5 17.4 10.9 BCL3 "BCL4, D19S37" ENSG00000069399 "BCL3 transcription coactivator" P20749 19 44747705-44760044 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 161.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 172.4;Squamous epithelial cells: 146.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 5.5;neutrophil: 19.8" "Lineage enriched" "Detected in all" 6 "granulocytes: 19.8" "Cell line enhanced" "Detected in many" "HDLM-2: 67.3;Karpas-707: 54.1;SiHa: 69.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002051, HPA047514" Approved Supported Nucleoplasm,Vesicles,Midbody Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Vesicles, Midbody" "CAB002051: AB_563428, HPA047514: AB_2680074" "prognostic favorable (9.67e-4)" "unprognostic (8.82e-2)" "unprognostic (2.81e-1)" "unprognostic (7.54e-2)" "prognostic unfavorable (4.01e-4)" "unprognostic (3.49e-2)" "unprognostic (2.34e-3)" "unprognostic (2.79e-1)" "prognostic favorable (3.74e-4)" "unprognostic (2.09e-2)" "unprognostic (9.23e-2)" "unprognostic (1.81e-1)" "prognostic unfavorable (3.13e-14)" "unprognostic (8.24e-2)" "unprognostic (1.36e-1)" "unprognostic (3.77e-2)" "unprognostic (3.04e-2)" 65.1 43.6 6.7 25.0 6.3 54.0 37.2 6.4 7.8 26.8 7.9 39.7 32.2 26.8 1.7 67.5 35.9 13.4 36.3 5.9 7.2 56.6 161.8 87.3 11.6 11.6 7.8 23.7 37.4 3.1 25.2 7.9 8.1 43.4 9.3 1.3 40.9 8.9 17.8 28.3 44.2 11.7 8.0 58.7 35.9 9.6 8.5 6.6 36.8 4.9 12.7 37.6 37.7 6.4 9.8 33.5 0.7 17.5 6.1 12.6 1.7 5.8 6.3 3.7 5.3 6.9 17.8 9.5 13.4 11.5 18.5 10.5 2.4 9.9 2.3 67.3 0.6 1.1 18.9 9.3 14.6 0.7 28.2 22.5 7.8 8.1 9.9 16.6 10.0 0.0 1.2 54.1 2.2 8.4 0.0 7.4 0.9 15.1 12.8 4.3 6.5 3.4 16.5 19.9 0.0 0.9 69.7 35.7 1.9 1.1 12.7 7.6 16.8 11.8 11.6 18.5 2.2 50.1 21.4 10.1 22.1 1.2 9.2 0.4 2.7 5.5 0.8 1.8 1.1 1.5 1.0 1.3 2.6 1.3 0.5 0.7 19.8 2.3 1.1 3.1 1.7 1.0 6.7 6.3 6.4 7.8 5.9 7.2 11.6 7.8 8.1 8.0 8.5 6.4 56.3 19.2 51.3 2.6 43.9 46.7 38.8 22.4 172.4 2.3 106.8 62.0 3.0 42.9 28.6 12.9 0.0 0.6 33.4 60.6 9.8 31.8 11.8 49.4 34.2 76.3 21.5 4.2 0.5 68.7 6.8 47.8 128.0 70.0 38.0 1.4 38.9 35.5 16.1 8.4 0.8 56.2 8.2 30.5 110.8 2.7 13.4 86.6 40.9 1.0 28.4 2.2 2.1 0.0 0.1 43.0 40.0 4.5 100.4 58.9 56.6 17.7 20.5 0.6 6.6 43.3 40.1 0.5 2.0 146.0 61.1 1.4 46.2 0.3 34.5 51.2 BEND7 "C10orf30, FLJ40283" ENSG00000165626 "BEN domain containing 7" Q8N7W2 10 13438484-13528974 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 167.3;Late spermatids: 268.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 17.5;hTERT-RPE1: 17.3" HPA037835 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nucleoli fibrillar center, Vesicles" "HPA037835: AB_10669722" "unprognostic (6.22e-2)" "unprognostic (1.80e-1)" "unprognostic (1.89e-1)" "unprognostic (1.33e-2)" "unprognostic (1.18e-2)" "unprognostic (4.62e-3)" "unprognostic (3.24e-3)" "unprognostic (3.52e-2)" "unprognostic (1.26e-1)" "unprognostic (5.02e-2)" "unprognostic (1.12e-1)" "unprognostic (1.06e-1)" "unprognostic (4.19e-3)" "unprognostic (1.57e-1)" "unprognostic (1.60e-1)" "unprognostic (1.58e-1)" "unprognostic (5.20e-3)" 8.0 6.0 4.7 2.4 4.9 0.7 9.4 6.5 4.7 7.4 4.9 11.2 16.5 7.3 13.6 2.2 12.4 6.5 7.4 5.0 4.9 18.5 9.0 9.1 1.1 5.1 5.9 8.3 12.1 14.8 10.3 4.3 5.9 5.7 6.6 15.4 15.1 6.5 16.4 3.2 19.3 6.1 4.7 3.0 11.2 16.3 5.6 0.5 23.5 13.3 1.0 6.8 4.4 4.4 9.9 5.9 6.0 2.2 0.1 0.0 8.7 3.8 0.1 9.3 5.6 2.4 17.5 0.0 5.1 7.3 5.2 0.4 9.8 2.1 8.3 0.0 8.7 0.0 0.0 11.4 3.9 0.0 0.0 0.2 5.7 1.2 0.0 17.3 10.3 1.4 4.3 0.0 9.3 4.0 0.1 0.0 1.8 0.0 1.0 0.0 4.4 0.0 8.0 1.3 0.4 4.7 10.7 0.0 0.1 9.1 0.1 4.7 9.2 1.1 13.8 11.6 4.8 0.0 0.0 0.0 3.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.7 4.9 6.5 4.7 5.0 4.9 5.1 5.9 5.9 4.7 5.6 4.4 33.6 22.4 11.6 23.5 1.9 3.4 23.6 1.1 1.8 14.4 15.4 11.4 11.0 22.8 9.8 20.2 8.4 3.0 2.6 13.2 3.9 13.0 167.3 25.0 5.8 16.7 7.8 0.0 7.5 16.5 2.9 8.0 9.7 36.2 6.3 14.7 22.5 9.6 3.0 1.7 10.2 8.5 6.1 9.4 1.9 268.7 5.0 2.5 3.6 24.4 4.5 20.3 12.3 47.7 0.7 21.8 9.5 6.0 0.5 23.9 45.2 52.0 9.7 32.2 0.0 14.1 8.4 21.5 20.0 3.3 1.8 2.5 3.5 3.4 10.3 36.1 BIRC5 "API4, EPR-1, survivin" ENSG00000089685 "Baculoviral IAP repeat containing 5" O15392 17 78214186-78225636 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis, Transcription, Transcription regulation" "Protease inhibitor, Repressor, Thiol protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.9;lymphoid tissue: 41.0;testis: 19.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 74.7;Early spermatids: 94.1;Erythroid cells: 166.7;Extravillous trophoblasts: 162.0;Spermatocytes: 191.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 14.1" "Lineage enriched" "Detected in many" 6 "T-cells: 14.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002830, CAB004270" Enhanced Supported "Cytokinetic bridge" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Cytokinetic bridge" "CAB004270: AB_628302, HPA002830: AB_1857672" "unprognostic (8.04e-2)" "unprognostic (3.51e-2)" "unprognostic (4.48e-3)" "unprognostic (2.72e-3)" "unprognostic (3.37e-1)" "unprognostic (3.84e-2)" "prognostic unfavorable (5.28e-6)" "prognostic unfavorable (4.49e-4)" "unprognostic (3.56e-3)" "unprognostic (4.53e-3)" "unprognostic (2.87e-3)" "unprognostic (6.67e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.77e-2)" "unprognostic (4.70e-2)" "unprognostic (1.59e-1)" "unprognostic (1.16e-1)" 0.9 1.1 0.3 8.5 0.5 37.9 5.1 0.6 0.6 1.9 0.4 6.7 7.9 1.6 0.0 12.8 0.6 1.1 0.5 0.4 0.4 0.7 2.1 1.9 16.2 0.6 0.6 0.4 0.6 0.2 0.2 6.1 0.5 0.6 8.0 0.1 1.8 0.2 1.1 5.8 7.6 4.3 0.4 5.8 3.7 19.6 1.0 41.0 0.4 0.1 16.3 2.6 3.2 0.8 139.1 126.2 111.3 121.5 6.7 11.3 41.0 103.6 57.5 144.0 94.2 104.0 52.9 140.7 41.5 60.5 108.7 71.9 113.6 66.6 125.2 48.2 157.5 93.2 71.4 123.1 0.8 90.8 67.0 3.9 4.5 79.8 59.2 21.0 103.5 104.3 118.8 116.0 112.6 79.7 195.5 86.2 83.4 96.3 218.0 100.5 180.2 108.4 34.5 50.2 136.8 94.8 80.3 88.6 71.7 54.1 117.5 84.8 39.5 173.1 152.6 76.0 150.4 83.3 72.2 163.3 63.3 37.8 154.4 0.0 0.0 0.0 0.7 0.0 0.1 2.4 4.1 2.8 0.8 0.2 0.0 0.4 0.5 2.4 0.0 0.2 14.1 3.1 0.3 0.5 0.6 0.6 0.4 0.4 0.6 0.6 0.5 0.4 1.0 0.8 1.2 0.0 20.0 0.0 15.9 8.2 3.7 12.2 2.8 0.7 7.7 8.6 2.3 2.8 10.8 0.0 0.0 74.7 3.3 10.7 0.0 2.0 94.1 5.4 5.1 8.8 3.0 166.7 0.4 0.0 162.0 15.1 8.6 6.9 9.5 42.7 12.8 2.7 52.1 0.0 0.2 17.1 10.2 13.7 13.8 68.4 3.1 9.6 1.8 0.0 0.6 0.4 7.2 0.0 0.3 0.4 2.5 0.7 50.2 2.8 3.2 0.1 2.6 0.5 6.6 0.9 15.2 191.1 58.2 31.3 6.5 19.2 10.1 3.4 38.8 6.3 BIRC6 BRUCE ENSG00000115760 "Baculoviral IAP repeat containing 6" Q9NR09 2 32357028-32618899 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Protease inhibitor, Thiol protease inhibitor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 272.0;Inhibitory neurons: 291.3;Oligodendrocytes: 361.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 9.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 9.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA074409, HPA074738" Approved Supported "Golgi apparatus,Vesicles,Mitotic spindle" Yes No "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Golgi apparatus, Vesicles" "Mitotic spindle" "HPA074409: , HPA074738: AB_2686710" "unprognostic (3.38e-2)" "unprognostic (8.13e-3)" "unprognostic (8.88e-2)" "unprognostic (7.06e-3)" "unprognostic (6.69e-3)" "unprognostic (9.01e-2)" "unprognostic (4.51e-2)" "unprognostic (2.07e-1)" "unprognostic (1.32e-1)" "unprognostic (1.86e-1)" "unprognostic (4.49e-2)" "unprognostic (4.00e-2)" "unprognostic (2.07e-2)" "unprognostic (1.30e-1)" "unprognostic (4.61e-1)" "unprognostic (7.32e-2)" "unprognostic (3.37e-1)" 4.6 4.7 3.1 6.7 9.7 11.3 8.9 13.9 5.7 7.7 6.3 7.6 5.0 6.8 5.2 5.3 6.2 5.8 4.9 4.6 3.7 7.6 8.9 5.4 9.6 6.4 5.5 12.0 14.7 10.9 2.9 6.9 7.3 6.2 7.5 15.5 5.5 5.9 6.1 6.7 5.4 6.1 4.4 8.5 7.1 6.8 5.6 14.7 11.4 8.8 9.7 7.2 3.1 16.3 21.7 17.8 16.1 7.9 14.9 19.1 11.3 10.8 14.1 11.0 11.3 14.2 5.7 23.6 7.3 19.7 13.2 10.1 22.9 15.1 13.9 18.8 10.5 31.2 11.3 10.7 7.9 32.4 11.9 12.4 6.9 18.0 16.2 10.1 17.7 5.4 25.6 10.0 11.9 9.3 15.5 7.5 11.7 9.2 10.5 14.6 26.6 8.2 9.2 23.4 11.7 18.4 18.6 10.8 8.2 12.5 6.4 11.5 28.7 13.0 13.3 9.1 15.3 13.9 20.0 30.6 10.1 15.1 8.7 9.7 0.9 0.6 1.3 0.7 1.8 0.8 1.0 1.2 0.7 1.8 1.1 1.4 1.5 1.6 1.5 1.6 1.0 0.5 3.1 9.7 13.9 5.7 4.6 3.7 6.4 5.5 7.3 4.4 5.6 16.3 53.9 32.1 30.5 239.3 74.8 46.0 28.6 34.7 41.5 60.8 40.0 23.4 45.8 38.6 42.7 36.8 191.8 35.0 93.4 70.1 1.9 26.9 45.9 39.3 58.0 49.8 32.5 34.3 272.0 31.2 22.0 39.7 68.3 63.1 29.9 52.1 45.7 47.5 29.8 69.0 291.3 43.3 26.4 54.7 60.0 17.6 45.4 59.1 23.2 202.4 67.2 34.9 64.9 231.8 361.3 34.3 30.3 59.0 70.9 46.4 48.5 22.6 30.6 88.2 39.5 56.0 49.1 53.7 46.2 49.7 54.8 38.0 72.4 52.8 45.3 44.0 BMS1 "BMS1L, KIAA0187" ENSG00000165733 "BMS1 ribosome biogenesis factor" Q14692 10 42782795-42834937 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ribosome biogenesis" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036589, HPA043081" Uncertain Enhanced "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli, Mitotic chromosome" "HPA036589: AB_10601460, HPA043081: AB_2678305" "unprognostic (1.46e-2)" "unprognostic (4.31e-1)" "unprognostic (7.09e-2)" "unprognostic (3.56e-2)" "unprognostic (3.11e-2)" "unprognostic (7.25e-3)" "prognostic unfavorable (1.06e-6)" "unprognostic (1.47e-1)" "unprognostic (1.20e-1)" "unprognostic (1.89e-2)" "unprognostic (3.81e-3)" "unprognostic (1.32e-2)" "unprognostic (2.16e-3)" "unprognostic (7.03e-2)" "unprognostic (1.80e-1)" "unprognostic (3.43e-1)" "unprognostic (4.82e-2)" 8.1 8.3 6.5 8.9 7.2 10.7 8.5 8.6 8.2 8.2 8.5 7.7 6.3 8.2 6.8 9.6 7.3 5.1 9.0 6.1 7.8 8.1 8.1 7.6 10.0 7.4 7.8 8.4 8.8 11.4 7.6 8.2 7.7 7.3 7.9 6.5 8.8 6.9 17.7 10.2 7.8 7.7 6.5 8.7 7.4 8.1 7.0 9.6 7.2 13.4 10.8 10.1 8.3 7.2 32.0 26.7 25.3 29.0 18.8 15.5 24.5 26.1 27.5 30.3 25.9 37.1 24.4 16.9 18.1 22.7 17.0 27.3 42.0 33.8 39.4 24.7 29.3 22.7 20.7 31.9 16.2 61.7 20.4 13.9 16.9 32.7 31.5 16.9 23.2 19.4 40.4 17.7 21.8 27.1 34.6 20.3 32.3 22.0 28.0 31.3 26.7 18.1 16.8 27.7 19.3 20.4 22.9 25.1 21.7 26.2 30.6 17.6 28.3 14.0 50.7 28.4 43.2 14.1 18.7 48.5 20.5 44.9 11.0 3.8 4.6 2.7 7.2 8.2 8.5 8.7 8.9 7.9 7.5 6.1 9.6 8.3 0.6 6.1 7.1 3.9 6.9 5.3 6.5 7.2 8.6 8.2 6.1 7.8 7.4 7.8 7.7 6.5 7.0 7.2 25.6 32.1 33.1 19.6 29.7 22.9 33.9 28.4 14.2 20.7 18.8 17.1 48.0 20.0 37.4 23.9 10.4 27.7 23.6 10.2 21.5 32.3 14.6 28.8 34.5 31.3 16.8 19.5 31.4 34.9 30.0 26.4 16.3 30.0 22.1 36.8 21.4 18.6 19.7 21.9 28.8 11.5 22.4 15.3 22.6 12.1 23.6 19.9 33.8 10.3 35.2 12.8 24.7 20.1 24.0 38.2 8.9 16.6 31.3 32.2 8.8 30.1 49.5 28.7 19.7 35.3 31.4 40.3 56.1 17.1 25.4 24.9 25.3 33.5 18.7 41.4 BOP1 KIAA0124 ENSG00000261236 "BOP1 ribosomal biogenesis factor" Q14137 8 144262045-144291438 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 76.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 223.5" "Low region specificity" "Detected in all" "HPA047869, HPA066764" Approved Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 26: Non-specific - Mitochondria" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA047869: AB_2680193, HPA066764: AB_2685716" "unprognostic (6.92e-2)" "unprognostic (5.03e-3)" "unprognostic (6.78e-2)" "unprognostic (2.06e-3)" "unprognostic (3.32e-1)" "unprognostic (2.16e-2)" "prognostic unfavorable (3.35e-5)" "unprognostic (2.25e-2)" "unprognostic (4.14e-1)" "unprognostic (3.31e-1)" "unprognostic (2.26e-2)" "unprognostic (7.00e-2)" "prognostic unfavorable (2.23e-7)" "unprognostic (7.83e-2)" "unprognostic (4.33e-1)" "unprognostic (8.49e-2)" "unprognostic (4.06e-3)" 18.1 17.8 6.8 8.8 6.9 9.7 16.3 7.7 10.9 16.1 3.5 17.3 5.6 18.2 1.0 26.0 13.2 2.8 24.4 7.6 5.5 16.7 21.5 13.3 8.0 7.1 6.0 11.1 32.0 5.6 16.9 3.7 6.5 15.3 1.9 1.1 13.2 3.1 76.6 21.4 14.9 3.1 4.7 20.4 15.4 20.1 6.2 5.4 17.0 8.1 3.6 19.3 16.5 6.1 45.0 87.4 11.8 50.6 6.4 7.7 41.4 30.5 6.5 30.3 19.1 66.3 25.4 54.1 50.1 11.6 11.5 34.9 21.2 36.2 6.9 47.8 82.5 68.4 54.4 49.7 15.1 30.8 35.6 15.5 17.0 25.2 22.1 5.7 18.8 48.3 70.1 18.1 11.9 112.8 82.4 37.6 28.3 45.1 223.5 61.4 17.6 82.2 12.5 30.1 64.7 25.8 32.5 41.9 20.3 5.5 30.6 27.7 36.6 27.8 83.3 37.1 88.5 16.5 11.7 45.6 20.3 48.6 36.7 0.0 2.2 1.3 1.9 2.3 2.1 2.5 2.2 2.5 3.0 1.8 2.0 1.8 0.1 1.8 2.0 2.0 2.0 1.2 6.8 6.9 7.7 10.9 7.6 5.5 7.1 6.0 6.5 4.7 6.2 6.1 12.8 9.6 5.1 3.9 16.7 0.5 18.7 0.0 13.1 9.8 12.7 13.8 7.2 10.0 3.7 11.0 0.0 25.2 20.9 18.7 5.9 25.8 11.2 7.5 10.7 12.0 26.9 22.1 4.4 21.7 45.3 13.2 17.3 8.3 10.2 13.5 4.6 14.8 21.5 15.2 3.5 11.5 0.0 11.1 0.0 24.3 10.5 12.8 0.0 1.0 16.2 16.7 18.6 5.0 2.8 26.4 11.3 9.8 25.4 39.5 11.3 17.2 1.5 4.6 13.1 12.9 15.1 13.9 53.4 25.7 0.1 17.8 11.8 29.6 31.8 14.3 BRCA2 "BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, XRCC11" ENSG00000139618 "BRCA2 DNA repair associated" P51587 13 32315086-32400268 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.8;lymphoid tissue: 3.1;testis: 2.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 115.4;Spermatogonia: 85.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" HPA026815 Uncertain Supported Nucleoplasm,Cytosol Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA026815: AB_10602692" "unprognostic (9.36e-2)" "unprognostic (2.50e-1)" "unprognostic (4.50e-3)" "unprognostic (1.06e-2)" "unprognostic (5.40e-2)" "unprognostic (2.26e-2)" "unprognostic (1.37e-2)" "unprognostic (1.15e-1)" "unprognostic (1.60e-2)" "unprognostic (2.01e-1)" "unprognostic (6.97e-3)" "unprognostic (4.06e-2)" "unprognostic (3.07e-9)" "unprognostic (2.36e-2)" "unprognostic (1.18e-1)" "unprognostic (1.88e-1)" "unprognostic (1.32e-1)" 0.2 0.1 0.0 1.3 0.0 5.8 0.5 0.0 0.0 0.2 0.2 0.7 0.5 0.3 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.1 0.3 0.3 2.1 0.1 0.1 0.1 0.1 0.0 0.0 1.0 0.1 0.1 0.8 0.0 0.2 0.0 0.0 0.7 0.5 0.3 0.1 0.9 0.6 2.7 0.2 3.1 0.2 0.0 2.0 0.5 0.2 0.1 4.7 4.0 6.0 5.0 0.6 1.4 7.0 4.8 3.1 5.5 5.0 10.6 6.0 15.9 3.2 2.1 7.6 6.1 5.5 2.9 10.5 10.5 3.1 10.3 2.5 3.5 0.1 15.4 4.9 0.2 0.0 10.3 6.9 0.4 4.5 8.1 7.0 5.5 6.4 5.1 11.8 8.3 8.3 4.9 2.3 11.4 17.3 3.0 1.4 5.4 2.4 4.6 5.9 2.4 2.2 2.2 2.9 7.3 1.3 6.3 6.8 7.0 6.7 2.0 3.3 8.0 2.7 5.7 5.8 0.0 0.3 1.5 0.5 0.7 0.1 1.7 0.4 0.4 0.3 2.2 0.5 0.4 0.8 0.5 0.8 3.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.1 4.4 9.6 2.6 0.0 12.4 2.5 3.3 2.5 2.2 0.0 4.3 3.3 1.9 0.0 1.8 0.0 0.0 14.1 10.5 4.8 0.0 2.5 5.2 4.4 6.3 5.5 1.2 29.5 0.7 1.6 12.7 5.8 10.7 4.6 3.8 26.9 1.4 0.8 9.5 0.0 0.5 4.4 0.0 7.5 11.0 4.4 2.1 14.4 3.6 4.7 20.1 0.3 0.0 0.0 0.6 1.2 1.8 1.2 27.8 1.2 1.0 0.6 2.9 0.0 13.1 8.3 5.3 115.4 85.6 8.0 1.3 5.5 7.9 4.2 7.8 2.3 BRF1 "BRF, GTF3B, hBRF, TAF3B2, TAF3C, TFIIIB90" ENSG00000185024 "BRF1 RNA polymerase III transcription initiation factor subunit" Q92994 14 105209286-105315589 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051918, HPA074990" Approved Approved "Nucleoplasm,Nuclear bodies" Yes No "Cluster 40: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Nuclear bodies" "HPA051918: AB_2681663, HPA074990: " "unprognostic (1.98e-1)" "unprognostic (4.45e-2)" "unprognostic (1.46e-2)" "unprognostic (2.51e-2)" "unprognostic (1.07e-1)" "unprognostic (7.52e-2)" "unprognostic (1.52e-4)" "unprognostic (2.67e-2)" "unprognostic (3.25e-1)" "unprognostic (2.26e-1)" "prognostic favorable (7.25e-6)" "unprognostic (8.83e-2)" "prognostic favorable (1.13e-4)" "unprognostic (1.85e-1)" "unprognostic (2.70e-1)" "unprognostic (5.39e-2)" "unprognostic (2.52e-1)" 10.5 11.4 19.7 5.5 22.2 6.5 10.5 23.1 23.6 12.5 12.9 11.1 7.6 12.1 4.2 10.4 12.8 6.0 12.2 17.1 19.2 11.6 13.1 8.4 8.1 31.8 24.9 13.0 15.1 10.3 20.4 6.0 29.7 12.0 4.2 7.5 10.1 6.3 17.7 11.2 10.3 4.6 18.7 12.6 11.2 14.6 25.4 7.3 10.5 9.6 5.8 11.5 9.9 37.4 12.6 28.0 11.8 25.3 10.3 11.4 11.9 17.4 11.2 15.4 12.2 20.2 18.8 9.4 16.9 12.0 7.5 24.2 14.4 11.7 8.4 25.2 14.2 11.5 15.1 9.9 11.5 13.7 24.3 11.3 10.1 9.3 11.5 7.8 11.3 19.7 13.1 7.5 7.6 40.9 16.2 17.1 8.6 20.7 27.7 28.2 8.1 9.6 7.6 29.9 37.5 27.8 18.4 14.0 16.0 5.4 33.4 18.9 16.8 12.1 9.6 22.7 14.2 13.8 11.5 8.9 14.5 11.3 16.9 0.4 1.2 2.0 1.6 1.0 1.1 1.5 1.1 1.6 1.2 1.4 1.4 1.3 0.5 2.5 4.0 3.1 1.6 1.6 19.7 22.2 23.1 23.6 17.1 19.2 31.8 24.9 29.7 18.7 25.4 37.4 11.5 3.2 5.9 17.6 11.4 7.5 7.1 4.5 8.6 18.8 10.7 9.0 8.5 2.8 6.3 3.7 16.7 11.4 15.5 16.2 3.9 5.8 2.3 26.5 10.9 9.5 9.6 6.3 18.3 7.1 8.9 7.7 14.8 16.5 2.5 16.0 8.9 11.3 7.2 30.3 20.8 11.7 4.1 6.7 10.3 1.4 6.5 7.8 8.8 10.3 5.3 7.1 4.1 15.1 34.2 4.8 6.5 4.5 13.4 7.7 8.9 6.1 12.4 20.0 0.0 9.6 8.2 9.2 12.7 7.7 8.8 9.3 11.6 13.2 12.5 5.1 BRIX1 "BRIX, BXDC2, FLJ11100" ENSG00000113460 "Biogenesis of ribosomes BRX1" Q8TDN6 5 34915677-34925996 "Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039614 Enhanced "Nucleoli,Mitotic chromosome" Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Mitotic chromosome" "HPA039614: AB_10963698" "prognostic unfavorable (2.18e-4)" "unprognostic (2.60e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (1.10e-5)" "unprognostic (1.82e-1)" "unprognostic (5.85e-3)" "prognostic unfavorable (4.11e-8)" "unprognostic (3.37e-2)" "unprognostic (3.84e-3)" "prognostic favorable (6.34e-4)" "unprognostic (1.24e-1)" "unprognostic (2.54e-2)" "prognostic unfavorable (3.07e-9)" "unprognostic (1.95e-2)" "unprognostic (1.29e-1)" "unprognostic (1.30e-1)" "unprognostic (2.09e-2)" 18.6 17.1 13.3 17.6 13.8 37.1 24.7 15.2 18.7 15.1 12.8 15.6 12.9 17.4 17.8 17.7 16.1 12.2 14.7 13.2 14.1 15.1 18.5 13.0 26.4 13.7 13.6 18.5 13.7 18.2 9.5 25.7 13.8 15.7 17.1 11.6 12.9 14.5 10.4 14.6 12.8 16.1 13.9 14.3 13.1 13.9 13.5 20.7 15.8 12.2 25.8 30.1 12.3 15.2 66.1 57.0 64.2 87.1 26.0 37.8 121.6 74.9 52.7 100.0 63.5 74.5 81.0 138.8 38.7 45.5 113.5 52.1 108.5 79.8 117.3 75.1 101.3 93.9 125.7 71.9 67.4 150.8 63.8 44.4 49.8 93.3 85.9 31.0 48.5 72.9 158.4 43.8 66.2 63.6 108.3 163.9 101.0 75.2 86.8 94.6 112.5 60.5 59.3 70.7 75.1 68.8 157.6 109.7 76.1 50.0 66.4 92.7 28.4 78.7 87.5 58.1 151.0 39.3 87.7 177.6 66.3 171.3 100.3 15.0 21.4 10.0 34.5 21.0 50.1 63.7 43.2 44.3 27.8 49.9 53.3 46.6 1.2 43.7 30.6 37.5 43.5 44.6 13.3 13.8 15.2 18.7 13.2 14.1 13.7 13.6 13.8 13.9 13.5 15.2 35.5 28.9 30.7 8.5 40.0 108.7 114.3 110.2 55.2 20.8 27.3 41.3 23.2 25.8 63.0 23.9 12.5 127.1 37.0 13.5 49.0 52.5 24.8 29.9 45.1 40.6 21.0 45.2 11.9 42.7 100.6 44.4 19.4 31.6 20.2 30.0 20.0 11.9 42.7 21.9 13.4 19.0 63.1 10.7 20.1 8.4 39.4 18.4 32.0 4.7 31.1 22.3 21.6 10.6 13.6 44.7 13.1 29.0 21.4 70.9 9.9 37.9 45.8 37.2 6.6 54.3 55.7 59.9 77.6 46.0 95.8 126.1 37.1 31.7 31.9 85.1 BTBD16 "C10orf87, Em:AC061711.1, FLJ25359" ENSG00000138152 "BTB domain containing 16" Q32M84 10 122271296-122338159 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 8.3;testis: 7.8;urinary bladder: 20.2" "Group enriched" "Detected in some" 9 "Early spermatids: 123.2;Late spermatids: 69.9" "Cancer enriched" "Detected in many" 14 "urothelial cancer: 18.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "RT4: 33.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA040529, HPA057638" Uncertain Uncertain Nucleoli,Cytosol Yes NA "Cluster 35: T-regs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 34: Spermatids - Unknown function" Nucleoli Cytosol "HPA040529: AB_2677022, HPA057638: " "unprognostic (1.41e-4)" "unprognostic (1.33e-1)" "unprognostic (5.97e-2)" "unprognostic (5.98e-3)" "unprognostic (2.08e-1)" "unprognostic (2.09e-3)" "unprognostic (2.88e-1)" "unprognostic (4.54e-2)" "unprognostic (1.76e-1)" "unprognostic (6.85e-2)" "unprognostic (2.48e-2)" "unprognostic (1.77e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (1.08e-1)" "unprognostic (1.60e-1)" "unprognostic (9.12e-2)" "unprognostic (9.44e-3)" 0.1 0.0 1.0 0.0 1.4 0.0 0.5 1.2 2.3 0.3 0.7 0.5 0.0 0.1 0.3 0.1 0.4 0.2 0.0 1.1 1.2 0.3 4.0 0.2 0.0 1.4 1.4 0.0 0.1 0.0 0.4 0.1 1.4 0.8 0.0 0.0 0.4 0.0 0.3 8.3 0.1 0.1 1.3 0.0 0.1 7.8 1.2 0.0 0.4 0.0 0.1 20.2 0.5 2.1 0.0 0.3 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.3 0.0 0.5 0.0 0.1 0.0 0.0 0.1 4.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 1.5 33.7 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.0 1.4 1.2 2.3 1.1 1.2 1.4 1.4 1.4 1.3 1.2 2.1 0.0 0.0 0.0 0.0 0.0 2.8 0.4 0.2 0.0 0.0 0.2 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 1.4 123.2 0.6 0.0 0.2 0.0 0.0 0.9 0.7 0.1 0.0 0.0 0.4 0.0 0.0 0.0 4.5 0.0 0.0 1.2 0.0 0.0 0.0 0.4 69.9 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.5 9.8 1.1 3.8 0.4 0.0 0.1 0.2 1.0 3.1 0.0 0.0 0.4 0.2 10.0 0.8 0.0 3.1 0.1 0.4 0.0 0.0 2.9 BUB1B "Bub1A, BUBR1, MAD3L, SSK1" ENSG00000156970 "BUB1 mitotic checkpoint serine/threonine kinase B" O60566 15 40161023-40221123 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.8;lymphoid tissue: 35.7;testis: 22.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 23.5;Spermatocytes: 79.2;Spermatogonia: 26.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA008419 Supported Cytosol Yes Yes "Cluster 24: B-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA008419: AB_1078308" "unprognostic (4.40e-2)" "unprognostic (2.23e-1)" "unprognostic (4.65e-2)" "unprognostic (2.44e-3)" "unprognostic (9.66e-2)" "unprognostic (3.52e-2)" "prognostic unfavorable (7.43e-6)" "prognostic unfavorable (3.56e-4)" "unprognostic (3.69e-3)" "unprognostic (2.32e-1)" "prognostic unfavorable (1.79e-4)" "unprognostic (1.76e-2)" "unprognostic (0.00e+0)" "unprognostic (3.75e-2)" "unprognostic (4.66e-2)" "unprognostic (2.20e-1)" "unprognostic (3.94e-2)" 0.4 0.5 0.1 6.7 0.1 17.8 1.6 0.3 0.2 1.0 7.7 4.6 4.7 1.2 0.3 5.2 0.6 0.6 0.3 0.3 0.1 0.3 0.4 1.0 12.6 0.0 0.1 0.2 0.2 0.2 0.1 3.4 0.1 0.4 6.0 0.1 0.9 0.2 0.0 3.5 4.1 2.1 0.0 3.1 2.4 22.2 0.2 35.7 0.5 0.0 15.0 1.5 1.7 0.0 66.5 32.8 103.0 41.5 2.5 7.1 33.2 60.9 34.2 64.6 55.7 48.1 25.0 59.7 33.5 22.7 59.0 72.6 98.8 33.2 70.5 51.8 52.1 86.4 83.6 45.5 0.2 79.0 45.7 1.6 2.0 39.2 37.1 12.9 47.7 66.5 76.4 61.7 65.6 22.5 62.5 48.9 70.2 55.6 36.8 66.5 83.7 45.2 19.9 33.1 67.1 40.8 38.0 35.9 13.3 45.1 41.9 40.9 27.6 49.3 51.8 49.2 55.5 32.1 58.2 95.6 26.3 87.8 65.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.1 0.2 1.1 0.0 0.1 0.0 0.1 0.0 0.8 0.0 0.1 0.1 0.1 0.3 0.2 0.3 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.1 3.2 1.1 0.3 1.8 0.8 0.3 1.0 1.8 0.7 0.9 2.0 0.8 0.0 1.9 0.0 0.0 5.4 0.6 1.8 0.0 0.4 3.0 0.9 1.4 1.0 0.0 23.5 0.7 0.0 6.7 2.4 5.6 2.1 0.0 12.9 1.1 0.3 5.2 0.0 0.7 2.5 0.0 1.9 1.7 3.3 1.5 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 1.5 0.4 12.6 0.3 0.3 0.1 0.2 0.2 6.6 0.2 1.7 79.2 26.8 6.9 0.3 0.8 1.8 0.8 5.4 0.6 BUD23 "MERM1, MGC19709, MGC2022, MGC5140, PP3381, WBMT, WBSCR22" ENSG00000071462 "BUD23 rRNA methyltransferase and ribosome maturation factor" O43709 7 73683025-73705161 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 119.9;Endometrial ciliated cells: 133.6;Exocrine glandular cells: 140.8;Pancreatic endocrine cells: 126.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 712.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052185 Approved Supported Nucleoplasm,Nucleoli Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 25: RPMI-8226 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nucleoli" "HPA052185: AB_2681753" "unprognostic (2.49e-1)" "unprognostic (1.87e-1)" "unprognostic (2.67e-2)" "unprognostic (4.79e-2)" "unprognostic (3.62e-3)" "unprognostic (8.54e-2)" "prognostic unfavorable (9.92e-4)" "unprognostic (1.17e-1)" "unprognostic (9.16e-2)" "unprognostic (9.20e-2)" "unprognostic (6.71e-2)" "unprognostic (4.20e-2)" "prognostic unfavorable (1.46e-4)" "unprognostic (5.15e-2)" "unprognostic (1.55e-1)" "unprognostic (1.46e-1)" "unprognostic (3.13e-3)" 39.8 49.2 34.5 40.0 36.7 58.7 43.4 36.4 39.8 36.3 41.0 48.6 47.0 38.6 72.3 41.7 58.9 34.5 87.9 36.1 39.0 53.3 47.2 38.5 52.6 37.0 36.1 37.8 70.8 49.2 45.1 30.7 36.3 37.8 47.7 20.3 55.9 42.2 128.0 43.8 40.3 41.4 36.4 42.1 44.9 130.0 36.6 44.7 56.5 78.4 51.7 51.9 32.8 38.5 142.1 151.8 53.6 429.2 72.0 64.2 91.1 95.1 83.3 118.5 96.1 211.4 182.6 163.6 48.9 99.5 204.0 97.0 124.8 91.0 108.4 116.6 147.1 72.0 174.8 86.7 91.2 200.3 98.8 57.3 102.2 103.2 93.9 59.7 77.4 130.3 285.4 288.9 103.7 219.6 128.0 277.8 130.2 317.8 172.2 110.5 106.8 712.0 132.5 100.2 163.4 124.4 126.3 329.2 146.5 53.0 207.9 159.0 85.2 101.8 130.3 130.0 208.3 99.5 192.6 275.5 232.3 155.6 218.0 54.8 64.9 60.6 112.0 74.2 124.9 175.3 127.1 122.5 122.9 153.5 132.8 121.5 11.9 125.4 68.0 190.9 150.6 132.6 34.5 36.7 36.4 39.8 36.1 39.0 37.0 36.1 36.3 36.4 36.6 38.5 67.0 44.8 64.5 0.0 26.5 0.0 0.0 0.0 0.0 0.0 75.4 85.7 0.0 0.0 42.7 46.0 0.0 75.7 64.1 0.0 97.8 119.9 0.0 133.6 51.2 28.6 0.0 0.0 0.0 140.8 82.7 24.5 0.0 79.6 46.7 49.2 0.0 0.0 70.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 0.0 0.0 21.2 0.0 0.0 0.0 0.0 126.0 0.0 0.0 16.5 0.0 0.0 103.5 78.7 0.0 0.0 0.0 26.4 0.0 0.0 0.0 0.0 106.7 28.1 73.0 0.0 0.0 BVES "HBVES, POP1, POPDC1" ENSG00000112276 "Blood vessel epicardial substance" Q8NE79 6 105096822-105137157 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion" "Developmental protein" "Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 27.8;skeletal muscle: 43.9;tongue: 29.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 34.2;Early spermatids: 36.1;Late spermatids: 55.3;Oligodendrocytes: 17.8;Spermatocytes: 24.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 29.7;WM-115: 30.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA014788, HPA018176" Enhanced Supported "Plasma membrane,Cell Junctions" Yes NA "Cluster 17: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cell Junctions" "HPA014788: AB_1845504, HPA018176: AB_1845503" "unprognostic (2.91e-1)" "unprognostic (2.45e-1)" "unprognostic (2.79e-2)" "unprognostic (1.73e-2)" "unprognostic (5.46e-2)" "unprognostic (3.66e-2)" "unprognostic (5.21e-2)" "unprognostic (2.22e-2)" "unprognostic (8.37e-2)" "unprognostic (4.49e-2)" "unprognostic (2.29e-2)" "unprognostic (8.92e-2)" "unprognostic (5.84e-3)" "unprognostic (3.77e-2)" "unprognostic (1.78e-1)" "unprognostic (2.02e-2)" "unprognostic (3.24e-4)" 2.9 0.7 2.6 2.3 7.1 0.2 1.5 5.8 3.6 2.5 4.6 14.9 1.4 5.8 1.7 5.3 2.8 1.8 27.8 2.7 4.3 1.6 0.3 1.9 0.6 7.3 5.6 1.0 0.6 0.7 2.4 3.5 7.4 5.2 3.3 0.2 1.4 10.0 43.9 0.7 3.0 17.7 5.2 0.3 6.9 11.5 5.2 0.2 1.3 29.3 0.4 9.3 2.2 10.8 1.3 2.0 7.6 1.3 10.9 14.9 3.3 5.8 4.1 8.8 11.6 0.5 0.0 0.0 0.0 10.9 14.7 0.1 3.3 2.0 8.1 0.0 2.8 0.0 1.0 0.3 2.4 0.0 0.6 8.7 6.9 13.6 1.1 6.6 4.0 3.3 0.1 19.3 19.7 0.1 0.2 1.0 1.6 0.0 0.0 5.7 29.7 0.0 0.0 0.0 9.9 17.1 3.7 0.1 7.7 5.5 0.0 20.0 8.9 14.0 0.0 0.0 15.3 1.8 0.8 0.0 8.3 0.0 30.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 2.6 7.1 5.8 3.6 2.7 4.3 7.3 5.6 7.4 5.2 5.2 10.8 2.1 0.0 0.0 1.6 0.0 0.3 0.4 0.1 0.6 0.0 0.4 1.0 34.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 36.1 1.9 4.4 3.1 0.0 0.0 3.3 0.0 0.2 2.6 0.0 6.0 0.0 0.9 2.2 0.1 2.3 0.0 0.6 0.0 0.0 0.0 1.9 55.3 1.2 0.5 0.0 3.7 1.0 0.0 0.0 5.0 17.8 0.1 0.0 3.4 0.0 0.5 0.1 0.1 0.1 0.0 13.1 11.8 4.4 24.4 5.4 0.1 0.9 0.1 0.2 1.3 0.0 0.3 BYSL Enp1 ENSG00000112578 "Bystin like" Q13895 6 41921499-41933046 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031217, HPA031219" Enhanced Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA031217: AB_10599488, HPA031219: AB_10601989" "unprognostic (6.12e-3)" "unprognostic (6.97e-2)" "unprognostic (2.90e-1)" "unprognostic (2.33e-3)" "unprognostic (4.38e-2)" "unprognostic (2.73e-3)" "prognostic unfavorable (6.43e-4)" "unprognostic (2.09e-2)" "unprognostic (2.51e-1)" "unprognostic (6.38e-2)" "unprognostic (1.30e-1)" "unprognostic (2.03e-1)" "prognostic unfavorable (2.15e-8)" "unprognostic (4.39e-2)" "unprognostic (2.18e-1)" "unprognostic (2.79e-3)" "unprognostic (5.99e-2)" 10.7 10.1 6.0 8.2 6.1 7.4 8.8 5.7 6.2 6.4 5.8 6.8 4.7 8.2 5.4 9.2 8.5 5.4 7.2 6.1 6.7 6.5 10.7 5.1 8.4 6.0 6.7 8.1 11.6 6.5 3.6 10.0 6.9 6.8 7.0 2.5 4.8 6.5 20.1 8.0 4.0 11.9 5.9 5.8 5.5 7.9 6.6 12.2 5.2 10.8 13.2 15.4 5.9 6.2 50.6 52.1 30.2 54.2 21.8 25.5 59.7 44.0 21.6 66.7 48.9 72.1 15.7 78.2 43.9 32.9 51.9 34.3 91.6 61.0 58.0 30.1 89.2 72.7 37.3 81.5 38.6 58.8 36.0 30.1 39.5 67.2 62.1 16.9 50.5 47.3 96.1 26.0 48.7 70.8 74.2 68.3 29.0 162.4 50.9 77.9 38.2 57.3 45.2 37.9 65.6 37.4 30.0 37.8 58.2 26.3 38.0 58.6 39.3 49.0 53.5 31.4 77.2 24.6 33.0 185.8 14.5 57.9 49.9 0.0 3.8 0.7 4.3 3.9 5.9 3.8 2.5 3.5 6.0 5.5 1.6 3.3 0.5 6.1 3.0 9.2 3.3 2.3 6.0 6.1 5.7 6.2 6.1 6.7 6.0 6.7 6.9 5.9 6.6 6.2 6.4 0.0 3.9 0.7 6.7 31.0 34.5 19.2 8.6 2.8 8.6 8.5 2.8 5.7 9.5 1.8 4.2 22.1 4.8 4.6 3.9 21.4 10.4 7.9 12.1 10.9 5.4 6.3 2.8 17.5 24.4 11.4 4.6 9.8 2.5 11.4 3.9 6.8 12.0 0.0 2.5 6.5 12.2 1.0 7.3 6.8 8.1 5.1 8.8 1.9 6.6 4.4 9.2 4.0 2.8 23.5 2.9 7.2 4.9 26.2 2.2 10.5 5.1 3.4 6.6 16.1 13.8 10.8 25.7 14.0 25.3 29.1 4.1 18.2 11.4 32.2 C10orf82 "Em:AC016825.4, MGC33547" ENSG00000165863 "Chromosome 10 open reading frame 82" Q8WW14 10 116663696-116670264 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "testis: 84.5" "Group enriched" "Detected in some" 113 "Early spermatids: 1053.9;Late spermatids: 1926.7" "Cancer enhanced" "Detected in many" "breast cancer: 2.4" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 103 "basophil: 10.2" "Lineage enriched" "Detected in single" 103 "granulocytes: 10.2" "Cell line enhanced" "Detected in some" "BEWO: 1.2;Hep G2: 2.8;NTERA-2: 1.4;SuSa: 2.5;T-47d: 3.5" "Not detected" "Not detected" HPA043022 Approved Mitochondria Yes NA "Cluster 46: Basophils - DNA binding" "Cluster 83: Testis - Spermatogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 34: Spermatids - Unknown function" Mitochondria "HPA043022: " "unprognostic (9.98e-2)" "unprognostic (2.09e-2)" "unprognostic (8.41e-2)" "unprognostic (2.11e-1)" "unprognostic (1.63e-2)" "unprognostic (9.52e-2)" "unprognostic (3.46e-3)" "unprognostic (3.48e-1)" "unprognostic (6.15e-2)" "unprognostic (1.50e-2)" "unprognostic (8.00e-2)" "unprognostic (1.47e-3)" "unprognostic (2.61e-2)" "unprognostic (1.94e-2)" "unprognostic (1.73e-1)" "unprognostic (1.07e-1)" 0.3 1.7 0.3 0.2 0.2 0.0 0.9 0.1 0.4 0.4 0.0 0.9 0.1 0.0 0.2 0.3 0.2 0.1 0.4 0.2 0.8 1.2 0.0 0.0 0.0 0.3 0.5 3.6 1.1 0.0 1.0 0.0 0.4 0.9 0.2 0.1 0.2 0.7 0.0 0.2 0.4 0.0 0.2 0.1 0.4 84.5 0.9 0.0 1.6 0.1 0.0 0.3 0.6 0.2 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.4 0.2 0.8 0.3 0.5 0.4 0.2 0.9 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 1.1 1.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1053.9 0.3 0.2 0.5 1.2 0.0 0.5 0.2 0.1 0.1 0.0 0.7 0.0 5.6 0.0 0.0 0.1 0.0 1.8 1.1 0.0 0.0 0.0 1926.7 9.0 0.6 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 5.3 0.0 0.7 0.1 0.1 0.0 0.0 13.1 0.4 0.2 10.5 8.0 0.0 0.0 0.0 0.1 8.0 1.2 0.3 C12orf66 FLJ32549 ENSG00000174206 "Chromosome 12 open reading frame 66" Q96MD2 12 64186316-64222296 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046743, HPA052855" Uncertain Supported "Lysosomes,Cytokinetic bridge" Yes No "Cluster 30: Non-specific - Translation" "Cluster 35: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" Lysosomes "Cytokinetic bridge" "HPA046743: AB_2679782, HPA052855: AB_2681973" "unprognostic (7.44e-3)" "unprognostic (2.38e-1)" "unprognostic (6.20e-2)" "unprognostic (2.70e-1)" "unprognostic (2.31e-1)" "unprognostic (4.62e-2)" "unprognostic (3.45e-2)" "unprognostic (2.08e-1)" "unprognostic (1.15e-1)" "unprognostic (2.94e-1)" "unprognostic (1.93e-1)" "unprognostic (3.60e-1)" "unprognostic (1.22e-1)" "unprognostic (1.57e-1)" "unprognostic (1.10e-1)" "unprognostic (7.46e-2)" "unprognostic (4.07e-2)" 2.9 4.2 3.6 3.4 5.3 1.7 5.4 4.0 4.8 2.8 1.9 2.8 3.1 2.6 4.8 4.2 3.9 2.5 2.3 3.5 4.3 5.5 8.6 2.8 4.9 4.0 4.4 3.9 5.2 5.7 2.6 2.1 4.5 2.3 3.1 1.6 2.9 2.3 4.4 5.6 2.5 2.3 3.7 5.0 3.0 3.4 4.3 3.3 5.6 3.2 4.8 2.6 3.0 6.8 5.5 8.7 1.6 4.7 4.3 7.2 4.5 3.0 3.7 4.4 2.7 2.7 4.3 17.4 4.1 2.4 7.1 6.3 6.9 5.3 4.7 13.3 4.6 6.3 2.1 2.5 5.6 6.9 3.6 5.6 9.0 5.7 10.3 5.0 3.2 12.0 8.8 11.3 4.4 10.6 7.9 6.0 7.7 6.5 6.8 4.0 4.9 13.4 6.6 6.4 3.8 3.8 4.9 6.7 4.8 4.2 10.8 4.4 2.5 4.4 2.9 4.4 2.9 14.9 13.2 9.7 6.6 5.9 5.0 0.5 2.6 0.2 3.3 2.6 5.7 8.5 6.4 5.0 4.3 7.2 8.7 8.4 0.2 4.0 1.8 3.1 10.8 4.2 3.6 5.3 4.0 4.8 3.5 4.3 4.0 4.4 4.5 3.7 4.3 6.8 3.4 3.2 2.7 5.5 9.3 2.4 8.8 3.4 7.4 2.1 5.9 4.1 2.7 7.2 5.5 9.2 2.1 6.3 4.0 1.9 9.8 4.1 9.2 3.3 4.0 3.9 4.2 3.4 7.1 5.2 3.9 3.5 7.1 3.6 1.3 3.6 1.8 10.8 4.9 0.0 5.5 2.7 4.1 6.3 2.6 7.3 4.7 4.3 1.8 1.0 2.1 2.5 1.0 3.5 17.4 2.6 2.6 1.9 2.8 4.7 2.1 12.9 2.4 1.6 0.0 7.4 2.8 4.4 8.8 6.9 4.3 1.8 5.8 4.3 3.7 4.3 C14orf39 SIX6OS1 ENSG00000179008 "Chromosome 14 open reading frame 39" Q8N1H7 14 60396469-60515543 "Plasma proteins, Predicted intracellular proteins" "DNA recombination, Meiosis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pituitary gland: 4.8;salivary gland: 4.6;testis: 10.8" "Cell type enriched" "Detected in some" 4 "Spermatocytes: 92.5" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Group enriched" "Detected in some" 16 "hypothalamus: 2.9;thalamus: 2.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 6.2;JURKAT: 28.3;MOLT-4: 23.9;RH-30: 6.2;U-2 OS: 12.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA059518 Uncertain Approved Nucleoplasm,Nucleoli Yes No "Cluster 77: Retina - Visual perception" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nucleoli" "HPA059518: AB_2684049" "unprognostic (6.17e-2)" "unprognostic (1.73e-3)" "unprognostic (3.00e-6)" "unprognostic (2.78e-1)" "unprognostic (6.97e-2)" "unprognostic (7.55e-4)" "unprognostic (2.12e-1)" "unprognostic (1.71e-1)" "unprognostic (2.17e-1)" "unprognostic (1.78e-1)" "unprognostic (7.46e-2)" "unprognostic (4.35e-1)" "unprognostic (1.50e-1)" "unprognostic (2.09e-1)" 0.3 1.8 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.8 0.4 0.2 0.5 0.0 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.1 0.0 0.1 0.1 1.2 0.0 0.5 4.8 0.0 0.0 1.1 0.0 2.7 4.6 0.1 3.0 0.0 0.1 0.1 0.0 0.0 0.3 10.8 2.4 0.1 0.2 3.7 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.8 6.2 0.0 0.0 0.0 0.0 0.3 4.5 0.0 0.7 0.0 0.1 0.0 28.3 0.0 0.0 2.0 0.0 23.9 0.3 3.0 0.0 1.4 0.0 6.2 0.0 0.4 1.7 0.1 2.6 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 12.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.9 0.1 0.1 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.6 0.5 0.0 0.9 0.0 0.1 0.7 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.2 0.0 0.0 2.8 0.0 0.0 0.3 0.0 0.0 1.3 0.0 0.0 0.0 0.0 3.3 0.9 0.0 0.0 0.0 0.0 6.8 0.3 0.0 0.0 1.0 0.0 12.3 0.0 1.0 0.7 0.0 0.0 0.7 0.0 0.8 0.0 0.0 1.2 1.1 0.0 10.0 0.2 92.5 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 C17orf100 LOC388327 ENSG00000256806 "Chromosome 17 open reading frame 100" A8MU93 17 6651762-6693202 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 32.9;Late spermatids: 48.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 10.0;SH-SY5Y: 9.4" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA046824 Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes No "Cluster 38: Basophils - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA046824: AB_2679825" "unprognostic (9.24e-3)" "unprognostic (1.79e-1)" "unprognostic (3.16e-1)" "unprognostic (6.37e-3)" "unprognostic (1.56e-1)" "unprognostic (1.90e-2)" "unprognostic (1.19e-1)" "unprognostic (8.99e-2)" "unprognostic (2.69e-1)" "unprognostic (2.02e-3)" "unprognostic (2.58e-3)" "unprognostic (4.72e-2)" "unprognostic (5.54e-3)" "unprognostic (4.52e-2)" "unprognostic (9.68e-2)" "unprognostic (9.44e-2)" "unprognostic (7.65e-2)" 0.9 1.6 4.1 1.7 4.9 0.5 1.5 3.3 4.8 1.9 2.2 1.6 3.0 1.6 2.2 4.3 2.0 1.1 0.6 3.5 4.5 2.4 3.6 1.2 3.2 3.2 3.7 1.3 4.5 3.5 9.5 0.8 3.2 2.5 1.5 5.3 2.8 1.0 0.6 7.3 3.0 0.8 3.4 2.9 2.4 5.5 4.1 1.7 3.3 0.8 1.2 1.9 2.3 3.9 1.1 2.1 4.6 1.5 0.7 1.3 2.2 0.6 3.4 1.4 2.7 3.2 1.5 1.3 2.3 1.1 3.6 4.1 0.9 2.2 2.0 5.6 6.3 1.2 2.4 10.0 1.6 0.2 3.2 1.8 2.1 0.7 1.5 4.1 0.8 6.7 1.6 1.2 1.8 2.4 1.4 2.1 0.6 1.9 1.4 2.6 0.8 2.0 2.9 1.0 4.8 9.4 2.9 0.3 3.4 1.4 2.5 0.3 1.3 1.3 2.6 0.8 1.1 1.7 1.2 0.8 1.1 0.4 3.1 3.9 0.9 4.0 1.2 1.3 1.6 2.3 2.2 1.4 1.6 2.5 2.5 1.4 0.8 1.4 1.3 0.5 1.5 0.9 4.1 4.9 3.3 4.8 3.5 4.5 3.2 3.7 3.2 3.4 4.1 3.9 1.7 0.0 1.7 0.0 3.2 2.8 5.4 4.8 8.0 3.8 4.9 5.0 0.4 0.0 4.9 0.0 2.1 1.7 0.6 3.8 1.9 4.1 32.9 3.0 3.0 1.8 7.7 1.3 1.4 3.2 1.8 1.6 4.1 2.9 8.9 4.7 0.0 0.0 1.2 1.7 1.4 7.1 10.2 0.0 1.3 48.7 0.9 0.7 1.8 1.0 1.2 5.1 1.0 1.5 2.2 3.3 2.6 1.9 0.9 4.5 9.0 2.1 2.4 5.8 6.6 1.9 3.0 16.4 4.6 7.0 3.0 1.5 1.7 3.8 3.9 5.1 C17orf50 ENSG00000270806 "Chromosome 17 open reading frame 50" Q8WW18 17 35760887-35765079 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 82 "testis: 105.6" "Group enriched" "Detected in some" 45 "Early spermatids: 769.0;Late spermatids: 1197.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 6 "HaCaT: 3.7;MOLT-4: 1.0" "Not detected" "Not detected" "HPA043184, HPA063464" Supported Nucleoplasm Yes NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 74: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA043184: AB_2678358, HPA063464: " "unprognostic (2.21e-1)" "unprognostic (1.07e-1)" "unprognostic (4.36e-2)" "unprognostic (4.01e-2)" "unprognostic (5.84e-2)" "unprognostic (5.12e-3)" "unprognostic (2.04e-2)" "unprognostic (1.97e-2)" "unprognostic (7.94e-2)" "unprognostic (5.36e-2)" "unprognostic (1.14e-2)" "unprognostic (2.71e-1)" "unprognostic (6.68e-2)" "unprognostic (4.67e-2)" "unprognostic (1.54e-2)" 0.1 0.1 1.2 0.0 0.9 0.0 0.1 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.8 0.7 0.1 0.0 0.1 0.0 0.4 0.7 0.0 0.2 0.0 0.3 0.0 0.1 0.1 0.0 0.3 0.0 0.1 0.1 0.2 0.2 0.0 0.0 0.1 0.1 105.6 0.6 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.4 1.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.7 0.8 0.7 0.4 0.0 0.7 1.2 1.4 0.0 0.1 0.0 1.4 0.0 0.2 1.2 0.9 0.0 1.0 0.8 0.7 0.4 0.7 0.1 0.0 0.6 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.2 0.0 0.4 0.5 0.6 0.3 0.0 0.1 9.2 0.0 0.0 0.2 0.4 0.0 0.0 769.0 1.8 0.0 0.5 1.2 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.4 2.0 0.0 0.0 1197.7 8.4 0.4 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.2 5.7 0.0 0.1 0.4 1.0 1.5 0.2 6.6 0.0 0.2 21.8 7.2 0.0 0.0 0.0 0.1 0.1 0.5 0.1 C1orf159 FLJ20584 ENSG00000131591 "Chromosome 1 open reading frame 159" Q96HA4 1 1081818-1116361 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 22.9" "Cell type enhanced" "Detected in many" "Early spermatids: 60.9;Late spermatids: 124.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010019, HPA075399" Approved Approved "Nucleoli rim,Mitotic chromosome,Intermediate filaments" Yes No "Cluster 34: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli rim, Mitotic chromosome" "Intermediate filaments" "HPA010019: AB_1078885, HPA075399: " "unprognostic (2.79e-1)" "unprognostic (9.46e-2)" "unprognostic (5.43e-2)" "unprognostic (1.16e-1)" "unprognostic (2.12e-1)" "unprognostic (2.60e-3)" "prognostic unfavorable (9.58e-6)" "unprognostic (1.34e-1)" "unprognostic (3.09e-1)" "unprognostic (2.04e-2)" "unprognostic (9.29e-2)" "unprognostic (3.26e-3)" "prognostic unfavorable (1.77e-6)" "unprognostic (4.10e-2)" "unprognostic (1.81e-1)" "unprognostic (7.56e-2)" "prognostic favorable (1.62e-4)" 4.0 4.8 9.6 1.6 8.0 2.4 3.8 0.9 10.4 5.3 3.2 6.1 1.8 4.2 1.1 8.6 4.8 2.2 4.3 9.4 1.0 7.7 6.7 3.9 1.8 6.3 2.7 4.3 3.7 0.7 5.3 1.4 2.8 6.9 0.6 1.6 4.6 2.3 2.2 5.0 4.1 0.5 0.7 5.5 6.0 22.9 5.4 1.8 4.5 0.3 0.9 5.5 5.9 6.9 15.7 12.0 5.6 10.0 1.5 1.6 13.3 9.0 2.1 7.8 5.1 6.5 14.7 4.3 10.8 2.8 6.4 12.2 2.5 7.1 2.2 8.6 18.2 3.1 19.6 7.0 3.6 5.5 7.3 3.2 2.8 3.3 1.6 2.3 3.8 6.4 18.6 3.1 2.8 11.9 10.2 13.2 4.7 5.9 19.7 12.0 6.7 8.5 4.7 4.7 11.8 16.1 6.8 12.2 7.6 1.6 7.8 6.5 5.2 8.3 8.8 11.9 9.2 5.6 8.3 7.8 6.8 14.9 6.5 8.1 2.6 1.4 2.6 2.6 2.8 2.5 2.5 3.0 1.7 2.2 2.5 2.6 0.5 2.7 1.8 2.2 0.9 2.3 9.6 8.0 0.9 10.4 9.4 1.0 6.3 2.7 2.8 0.7 5.4 6.9 6.3 0.0 7.7 20.2 3.4 7.5 3.6 6.2 4.6 5.9 8.9 6.6 2.3 5.7 7.1 9.2 4.2 5.0 4.9 13.6 1.9 8.2 60.9 8.6 8.2 4.4 4.2 5.2 26.5 7.0 14.0 4.2 20.4 9.0 5.7 9.0 3.3 5.3 3.9 13.5 21.8 7.4 6.1 1.0 4.8 124.1 2.8 3.9 3.6 2.8 6.0 3.2 9.2 10.6 24.5 7.8 3.5 1.5 6.9 5.1 3.4 1.8 10.4 8.2 0.0 3.5 4.8 18.3 6.8 4.2 7.0 4.9 4.6 4.4 9.4 4.9 C21orf91 "C21orf14, C21orf38, CSSG1, EURL, YG81" ENSG00000154642 "Chromosome 21 open reading frame 91" Q9NYK6 21 17788974-17819386 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 59.0" "Cell type enhanced" "Detected in many" "Early spermatids: 345.8;Late spermatids: 98.6;Oligodendrocytes: 103.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 111.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 107.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018288, HPA049030" Approved Approved "Microtubules,Cytokinetic bridge" Yes NA "Cluster 2: Granulocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" Microtubules "Cytokinetic bridge" "HPA018288: AB_1845710, HPA049030: AB_2680605" "unprognostic (3.28e-1)" "unprognostic (3.41e-2)" "unprognostic (3.12e-2)" "unprognostic (4.51e-2)" "unprognostic (6.19e-2)" "unprognostic (1.11e-3)" "unprognostic (2.42e-1)" "unprognostic (8.81e-3)" "unprognostic (2.79e-1)" "unprognostic (1.97e-1)" "unprognostic (3.25e-1)" "unprognostic (5.49e-2)" "unprognostic (1.24e-2)" "unprognostic (6.80e-2)" "unprognostic (1.59e-1)" "unprognostic (6.49e-2)" "unprognostic (9.90e-3)" 6.3 4.8 11.5 9.8 26.7 8.2 8.2 22.0 16.3 6.2 4.4 4.7 5.1 9.2 4.3 8.3 6.7 6.0 5.4 13.3 15.5 5.3 8.7 7.9 15.4 26.0 21.2 8.0 2.8 4.9 2.7 13.5 26.6 5.3 5.2 5.7 5.0 3.6 2.7 18.9 5.5 7.6 20.9 9.8 6.3 24.4 20.7 19.2 5.7 5.5 13.0 8.3 4.1 59.0 7.2 1.2 15.6 0.1 3.9 7.3 6.9 10.4 18.6 10.1 8.9 6.5 3.7 25.2 5.1 4.2 14.1 5.7 17.1 13.4 8.7 27.5 9.2 16.9 13.2 4.1 8.8 20.6 9.2 5.3 14.6 13.3 21.5 7.1 2.8 10.3 12.1 107.9 7.7 4.5 28.8 6.1 16.4 1.7 5.7 21.9 29.9 10.2 6.8 12.0 6.2 14.4 13.1 10.1 47.2 7.0 6.1 11.6 4.8 44.2 13.8 0.2 6.8 28.6 37.7 21.5 3.5 18.9 17.3 111.1 11.2 56.8 20.9 11.9 29.8 14.0 19.3 22.7 13.9 11.7 14.9 19.7 24.9 20.7 12.2 3.5 36.9 12.0 11.5 26.7 22.0 16.3 13.3 15.5 26.0 21.2 26.6 20.9 20.7 59.0 20.2 19.2 11.1 1.6 26.4 27.9 10.1 57.9 63.2 12.6 14.4 10.4 7.4 4.3 27.1 5.5 16.7 17.3 18.8 4.4 1.9 4.8 345.8 14.5 13.8 21.3 10.7 5.5 0.8 6.9 12.2 12.0 9.2 14.4 39.9 11.3 7.5 6.8 5.8 15.2 0.8 5.0 18.3 7.2 14.0 98.6 23.6 9.7 21.4 3.7 30.7 3.5 48.4 7.5 103.4 4.4 5.9 17.0 27.6 11.0 3.4 6.4 19.3 13.0 6.6 20.1 12.1 38.7 24.1 21.4 27.6 80.2 38.9 22.1 3.8 7.7 C9orf72 "DENND9, DENNL72, MGC23980" ENSG00000147894 "C9orf72-SMCR8 complex subunit" Q96LT7 9 27535640-27573866 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Guanine-nucleotide releasing factor" "Amyotrophic lateral sclerosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 127.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 24.3;classical monocyte: 32.0;intermediate monocyte: 44.7;myeloid DC: 25.2;neutrophil: 34.3;non-classical monocyte: 36.9" "Group enriched" "Detected in all" 8 "dendritic cells: 25.2;granulocytes: 34.3;monocytes: 44.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023873 Uncertain Supported "Vesicles,Midbody ring,Cytosol" "Intracellular and membrane" Yes NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 41: Macrophages - Immune response" "Vesicles, Cytosol" "Midbody ring" "HPA023873: AB_1845834" "unprognostic (1.78e-2)" "unprognostic (5.01e-2)" "unprognostic (7.63e-2)" "unprognostic (9.78e-3)" "unprognostic (1.46e-1)" "unprognostic (1.32e-1)" "unprognostic (1.59e-1)" "unprognostic (1.99e-3)" "unprognostic (2.45e-1)" "unprognostic (2.05e-2)" "unprognostic (2.16e-2)" "unprognostic (9.81e-2)" "unprognostic (1.44e-2)" "unprognostic (9.29e-2)" "unprognostic (1.10e-1)" "unprognostic (2.89e-2)" "unprognostic (9.13e-2)" 11.7 12.1 9.5 16.6 9.5 25.3 9.4 21.0 12.5 9.8 12.4 8.8 6.8 12.0 11.3 7.6 16.0 10.2 9.3 9.7 13.5 7.0 16.0 17.7 9.2 14.6 11.9 24.2 9.6 6.9 16.2 12.1 12.5 14.2 7.8 31.3 6.7 5.8 14.9 8.8 8.3 8.6 12.4 16.8 7.8 17.6 11.3 11.1 13.1 9.9 8.8 9.2 8.5 14.5 4.4 3.7 28.7 4.4 5.7 7.0 4.4 5.9 4.9 3.5 1.8 0.4 1.4 10.2 3.7 5.3 7.5 3.1 9.4 7.2 2.5 19.8 3.6 4.9 11.0 3.0 8.9 3.4 5.2 7.3 8.6 0.8 16.1 3.5 7.6 11.1 9.8 18.6 4.3 0.8 6.6 5.0 14.2 6.8 16.0 2.4 9.5 5.1 2.8 3.3 9.9 24.4 4.0 4.4 3.7 10.9 3.7 2.9 6.6 0.0 14.5 8.6 4.0 4.8 15.8 6.8 11.4 11.0 3.8 24.3 32.0 2.4 1.9 44.7 3.3 3.4 2.7 2.5 25.2 2.5 4.6 2.9 34.3 4.3 36.9 3.9 4.0 10.0 9.5 9.5 21.0 12.5 9.7 13.5 14.6 11.9 12.5 12.4 11.3 14.5 15.4 16.0 14.7 19.2 43.2 35.9 50.7 15.0 26.2 22.1 7.2 6.6 15.6 4.3 15.2 7.3 20.9 21.2 11.7 5.0 1.9 8.4 2.6 94.4 11.8 15.0 11.4 3.0 53.0 9.3 7.3 18.7 16.8 57.6 16.5 18.4 8.2 9.3 25.8 11.8 58.9 12.5 10.2 71.9 127.8 4.2 6.2 94.8 19.6 42.2 58.2 45.2 3.1 30.2 60.9 8.6 11.1 3.8 10.7 30.0 4.1 5.4 80.7 27.5 0.0 17.5 20.6 29.2 20.9 15.2 29.1 34.6 18.2 7.9 5.1 37.6 CALD1 "CDM, H-CAD, L-CAD" ENSG00000122786 "Caldesmon 1" Q05682 7 134744252-134970729 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 916.1" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1190.3;Leydig cells: 1745.0;Peritubular cells: 2005.6;Sertoli cells: 2294.3;Smooth muscle cells: 2549.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "neutrophil: 1.9" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "BJ hTERT+: 736.3;fHDF/TERT166: 1202.8;U-138 MG: 733.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000006, HPA008066, HPA017330" Enhanced Enhanced "Plasma membrane,Actin filaments" Yes No 39000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Actin filaments" "CAB000006: AB_2065456, HPA008066: AB_1078378, HPA017330: AB_1845917" "unprognostic (2.16e-2)" "unprognostic (1.19e-2)" "unprognostic (2.80e-3)" "unprognostic (3.05e-2)" "unprognostic (4.51e-2)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (1.22e-2)" "prognostic unfavorable (3.73e-4)" "unprognostic (2.07e-1)" "unprognostic (1.27e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.84e-5)" "unprognostic (6.52e-3)" "unprognostic (1.14e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-3)" 225.8 119.2 27.3 164.9 35.0 1.3 161.1 28.1 47.6 241.6 37.2 916.1 80.3 523.3 150.7 275.6 304.4 203.2 115.0 26.9 29.1 134.7 224.4 155.5 75.4 32.3 30.4 326.2 52.5 32.7 53.3 430.0 30.9 348.9 149.8 13.1 70.3 781.7 46.5 76.0 233.1 688.4 27.9 129.2 324.2 52.7 33.4 28.5 114.1 75.2 34.4 505.3 208.0 28.8 115.9 75.3 163.3 146.1 572.7 464.8 161.6 661.6 736.3 227.2 246.6 138.3 3.5 0.7 153.3 1202.8 148.1 26.9 106.0 202.3 308.4 1.5 38.9 4.0 87.8 94.7 375.6 1.5 0.8 360.9 153.6 252.8 147.4 343.6 193.0 0.0 0.6 1.6 338.7 0.3 0.6 3.2 197.7 0.1 25.6 1.4 146.6 2.3 46.9 32.2 29.0 72.1 235.3 31.7 90.0 491.0 7.2 1.4 508.5 733.2 130.0 143.8 230.3 0.9 1.1 1.3 259.0 0.8 573.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.9 0.2 0.0 0.0 0.0 2.9 27.3 35.0 28.1 47.6 26.9 29.1 32.3 30.4 30.9 27.9 33.4 28.8 400.6 22.4 17.6 43.1 7.3 420.4 379.6 218.8 164.4 172.0 115.5 466.1 456.5 228.8 33.5 44.1 6.2 202.7 5.0 0.3 23.5 392.6 61.0 89.4 1190.3 432.9 3.6 16.0 95.4 23.6 903.9 886.9 16.3 206.2 5.1 251.0 422.0 638.4 43.5 92.5 58.3 1.2 28.5 21.0 112.8 83.6 1745.0 38.8 336.2 94.6 8.4 140.6 6.2 98.5 158.8 146.0 0.2 2005.6 4.2 456.9 0.1 332.1 11.3 21.2 2294.3 326.1 2549.3 12.1 12.2 70.1 171.8 276.6 27.5 414.1 0.8 36.7 CALML4 "MGC4809, NY-BR-20" ENSG00000129007 "Calmodulin like 4" Q96GE6 15 68190705-68206079 "Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 91.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 49.2;Gastric mucus-secreting cells: 31.6;Paneth cells: 39.3;Proximal enterocytes: 36.2;Respiratory ciliated cells: 107.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 184.3;non-classical monocyte: 216.9" "Lineage enriched" "Detected in many" 7 "monocytes: 216.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051109 Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" Yes No "Cluster 51: Monocytes - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA051109: AB_2681346" "unprognostic (1.69e-2)" "unprognostic (1.78e-1)" "unprognostic (4.97e-2)" "unprognostic (8.50e-2)" "unprognostic (1.63e-1)" "unprognostic (3.71e-2)" "unprognostic (4.05e-2)" "unprognostic (6.53e-2)" "unprognostic (6.77e-2)" "unprognostic (2.10e-1)" "unprognostic (4.19e-3)" "unprognostic (6.24e-2)" "unprognostic (3.85e-2)" "unprognostic (7.92e-3)" "unprognostic (2.46e-1)" "unprognostic (7.49e-2)" "unprognostic (1.32e-1)" 5.2 5.1 2.9 14.5 2.9 4.5 3.1 3.9 3.8 9.2 12.6 70.1 91.9 3.3 1.4 2.1 19.3 18.7 1.2 3.1 2.7 29.1 15.0 5.1 3.9 2.8 2.7 1.7 7.0 0.9 3.5 5.4 2.9 6.2 64.7 4.3 2.2 4.4 3.4 4.8 76.0 7.3 2.4 5.9 15.6 3.3 3.0 4.5 1.6 0.7 4.0 3.5 2.3 3.3 3.4 11.6 7.9 4.8 1.6 1.7 5.7 2.2 2.3 4.8 3.0 22.1 29.8 3.7 3.0 1.9 3.7 15.1 18.2 2.8 2.0 3.3 16.9 6.7 21.6 7.9 3.5 5.8 14.7 1.6 4.4 1.8 3.4 3.0 5.9 10.8 6.2 3.9 0.7 10.2 14.5 12.6 8.5 24.1 3.4 30.1 8.1 8.2 1.3 6.0 4.4 4.3 3.5 3.2 9.9 3.1 2.8 12.6 3.5 5.0 4.5 9.2 8.7 14.4 9.4 10.0 3.3 14.9 2.2 0.1 43.7 0.2 0.1 184.3 0.6 0.6 0.6 0.2 29.1 0.1 0.5 0.3 21.3 0.0 216.9 1.4 0.4 18.3 2.9 2.9 3.9 3.8 3.1 2.7 2.8 2.7 2.9 2.4 3.0 3.3 1.3 0.0 1.5 3.3 0.7 1.5 0.8 2.8 1.8 11.1 0.4 0.1 0.3 12.8 15.8 3.7 0.0 0.5 0.3 49.2 0.0 2.5 6.5 9.4 0.6 6.4 7.7 1.3 3.8 4.3 0.5 3.2 31.6 0.4 0.0 0.4 5.0 8.1 3.9 8.4 4.0 17.1 0.0 11.7 1.5 0.5 3.7 8.1 0.0 4.7 3.9 2.0 2.1 3.0 3.4 3.0 39.3 6.8 2.4 1.1 36.2 25.4 107.8 3.1 0.0 1.1 0.7 0.0 0.4 1.3 2.0 0.1 1.2 0.1 21.1 1.1 CAMKV "MGC8407, VACAMKL" ENSG00000164076 "CaM kinase like vesicle associated" Q8NCB2 3 49857988-49869935 "Enzymes, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "brain: 91.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 12.2;Early spermatids: 6.3;Excitatory neurons: 32.7;Inhibitory neurons: 27.0;Late spermatids: 7.8" "Group enriched" "Detected in some" 11 "glioma: 4.0;testis cancer: 5.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.6;CACO-2: 6.1;HAP1: 10.3;NTERA-2: 34.1;RPMI-8226: 6.9;SCLC-21H: 17.7;SH-SY5Y: 8.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007656, CAB034931" Enhanced Supported Approved "Nucleoplasm,Cytokinetic bridge" Yes NA "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Cytokinetic bridge" "CAB034931: AB_2068550, HPA007656: AB_1078391" "unprognostic (9.47e-4)" "unprognostic (5.65e-3)" "unprognostic (1.42e-1)" "unprognostic (2.70e-7)" "unprognostic (2.76e-1)" "unprognostic (7.95e-4)" "unprognostic (3.09e-2)" "unprognostic (2.61e-1)" "unprognostic (1.48e-1)" "unprognostic (4.30e-3)" "unprognostic (1.72e-1)" "unprognostic (8.11e-2)" "unprognostic (1.00e-3)" "unprognostic (7.61e-2)" "unprognostic (9.51e-2)" "unprognostic (1.67e-3)" 0.0 0.8 66.5 0.0 91.8 0.0 0.0 0.0 84.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 73.3 19.0 0.1 0.0 0.0 0.0 0.2 8.7 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.1 0.1 0.0 12.9 0.0 0.1 2.0 37.2 0.0 0.0 0.0 0.0 0.0 0.0 39.2 0.0 0.2 7.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.1 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.8 0.0 0.0 0.1 0.9 0.2 34.1 0.0 0.2 1.3 0.0 6.9 0.0 0.0 17.7 8.3 0.0 0.0 0.0 1.3 0.0 2.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 66.5 91.8 0.0 84.9 73.3 19.0 0.2 8.7 0.0 12.9 37.2 39.2 0.0 0.0 0.0 3.9 0.0 0.3 0.0 0.0 0.0 12.2 0.1 0.1 0.7 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 1.2 0.0 32.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.3 27.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 4.7 0.0 0.2 0.0 2.5 3.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.0 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.3 0.0 0.0 0.1 0.0 CAMSAP1 "DKFZp434F195, FLJ31228" ENSG00000130559 "Calmodulin regulated spectrin associated protein 1" Q5T5Y3 9 135808487-135907546 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 105.5" "Group enriched" "Detected in many" 6 "Cone photoreceptor cells: 339.9;Rod photoreceptor cells: 236.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020527, HPA024161" Approved Supported "Mitotic spindle,Cytosol" Yes No "Cluster 34: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 9: Photoreceptor cells - Phototransduction" "Mitotic spindle, Cytosol" "HPA020527: , HPA024161: AB_1845967" "unprognostic (3.18e-3)" "unprognostic (4.16e-2)" "unprognostic (6.44e-2)" "unprognostic (1.57e-2)" "unprognostic (6.00e-2)" "unprognostic (1.43e-2)" "unprognostic (1.79e-3)" "unprognostic (1.22e-1)" "unprognostic (2.75e-1)" "unprognostic (6.13e-2)" "unprognostic (1.41e-1)" "unprognostic (9.16e-2)" "prognostic favorable (3.09e-5)" "unprognostic (1.12e-1)" "unprognostic (1.15e-1)" "unprognostic (1.03e-1)" "unprognostic (2.66e-3)" 6.7 7.4 12.5 5.5 12.7 10.3 5.4 12.7 12.6 9.2 2.5 7.4 3.2 7.5 5.2 20.0 7.7 5.2 7.8 14.1 9.8 5.1 4.3 6.8 5.8 8.3 9.3 10.7 7.9 6.1 8.7 5.2 8.8 6.2 3.5 105.5 7.5 6.5 32.8 10.4 4.4 6.9 5.6 5.3 5.0 18.1 11.5 11.1 4.4 17.5 6.9 7.4 11.7 11.6 15.4 22.3 36.0 25.5 8.2 7.1 17.6 12.2 10.2 13.0 9.8 19.7 13.2 7.1 17.0 15.4 16.7 30.8 19.0 13.2 9.7 24.0 10.5 10.3 24.9 9.9 12.4 18.0 14.8 9.5 16.3 16.6 22.6 12.3 14.8 15.5 21.4 15.0 17.1 27.5 16.8 11.0 20.4 18.2 15.8 32.5 29.7 17.4 12.8 18.7 39.1 38.2 15.6 11.2 17.0 11.7 15.9 14.6 18.3 24.6 19.0 18.3 20.9 7.3 14.7 19.2 16.0 12.0 14.5 1.5 0.3 0.0 0.2 0.4 0.4 0.6 0.4 0.3 0.2 0.1 0.3 0.4 0.1 0.2 0.3 0.2 0.3 0.3 12.5 12.7 12.7 12.6 14.1 9.8 8.3 9.3 8.8 5.6 11.5 11.6 6.3 6.4 3.9 31.6 5.5 22.7 17.4 10.8 9.6 34.4 11.8 9.8 14.0 4.3 15.7 3.7 339.9 12.6 5.8 4.5 0.0 11.8 13.1 41.5 13.2 8.8 12.6 6.6 37.7 8.9 3.5 6.6 8.2 32.4 6.3 20.4 7.5 8.2 10.3 16.8 34.1 4.4 10.2 8.1 13.5 15.8 5.9 11.7 12.4 25.3 12.2 19.2 4.1 27.2 35.9 15.7 3.0 6.0 11.9 14.2 2.7 4.3 37.1 236.1 13.1 16.8 11.7 24.4 34.4 35.2 31.7 5.6 6.5 15.6 4.5 24.8 CAPG "AFCP, MCP" ENSG00000042493 "Capping actin protein, gelsolin like" P40121 2 85394753-85418432 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 548.8;Hofbauer cells: 1107.4;Macrophages: 432.1;monocytes: 432.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 1136.5;classical monocyte: 1139.3;eosinophil: 712.7;intermediate monocyte: 431.6;memory B-cell: 575.6;myeloid DC: 1363.2;naive B-cell: 516.8;NK-cell: 605.5;plasmacytoid DC: 959.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 563.6;HMC-1: 972.7;SK-MEL-30: 722.2;THP-1: 513.5;U-937: 569.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018843, HPA019080, HPA019092" Enhanced Enhanced Nucleoplasm Yes No 5400000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "HPA018843: AB_2669948, HPA019080: AB_1845979, HPA019092: AB_1845980" "unprognostic (2.82e-2)" "unprognostic (1.37e-1)" "unprognostic (8.80e-2)" "unprognostic (1.28e-2)" "unprognostic (4.37e-2)" "unprognostic (7.52e-2)" "prognostic unfavorable (3.22e-5)" "unprognostic (8.83e-2)" "unprognostic (3.22e-2)" "unprognostic (1.54e-1)" "unprognostic (5.70e-3)" "unprognostic (1.75e-1)" "prognostic favorable (2.96e-4)" "unprognostic (1.45e-1)" "unprognostic (7.68e-2)" "unprognostic (5.30e-3)" "unprognostic (7.89e-3)" 92.4 26.3 42.8 82.4 44.2 159.3 94.9 46.3 79.6 119.1 37.5 56.9 30.3 50.0 46.2 289.5 48.7 44.4 19.2 41.7 51.1 201.1 8.9 175.7 117.9 60.2 46.3 19.7 44.9 151.7 27.2 26.1 57.2 76.5 42.9 4.2 111.8 38.0 16.5 219.9 54.2 24.5 57.5 46.2 94.4 26.0 66.1 58.0 162.3 5.8 109.5 97.1 174.8 79.4 165.5 75.9 0.7 6.9 50.2 102.8 83.7 59.6 6.1 51.2 49.8 9.4 563.6 28.1 96.6 116.0 64.0 181.1 0.2 113.7 23.0 142.0 4.4 74.3 128.0 29.3 40.6 44.8 972.7 93.8 80.5 53.8 70.3 3.6 37.5 143.8 8.2 60.1 38.1 150.1 101.3 414.8 23.2 166.5 112.8 87.3 13.3 11.8 220.6 77.7 0.8 1.4 86.9 128.4 722.2 44.2 40.0 513.5 148.7 111.6 26.8 4.6 2.4 1.4 6.2 10.3 259.5 569.5 1.5 1136.5 1139.3 712.7 12.2 431.6 39.2 575.6 107.8 41.1 1363.2 516.8 30.5 13.9 162.9 605.5 131.3 959.7 122.1 977.9 42.8 44.2 46.3 79.6 41.7 51.1 60.2 46.3 57.2 57.5 66.1 79.4 6.6 19.2 24.5 3.3 84.7 121.2 167.5 265.0 60.9 0.8 86.8 70.4 1.3 51.5 119.6 316.3 0.0 34.3 91.5 211.0 211.3 113.8 4.1 33.0 10.3 16.2 28.8 16.0 0.2 91.5 324.0 34.7 124.9 63.9 548.8 1.2 3.6 1.1 1107.4 1.7 0.2 55.9 50.8 141.6 337.2 15.2 46.9 432.1 147.7 1.0 432.4 43.6 11.3 0.5 0.1 405.8 205.4 22.6 17.2 106.0 74.1 168.5 48.8 1.7 13.1 2.0 54.0 9.6 33.1 167.4 169.5 35.7 101.9 0.9 83.9 253.1 CAPS2 ENSG00000180881 "Calcyphosine 2" Q9BXY5 12 75275979-75390928 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 11.8" "Cell type enhanced" "Detected in many" "Astrocytes: 85.5;Excitatory neurons: 133.8;Inhibitory neurons: 95.8;Oligodendrocyte precursor cells: 117.1;Oligodendrocytes: 102.6;Respiratory ciliated cells: 77.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA039542, HPA040004" Uncertain Approved Nucleoplasm,Nucleoli,Vesicles,Centrosome Yes No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoli "Nucleoplasm, Vesicles, Centrosome" "HPA039542: , HPA040004: AB_10794758" "unprognostic (1.38e-2)" "unprognostic (1.21e-1)" "unprognostic (7.26e-2)" "unprognostic (5.10e-2)" "unprognostic (3.05e-2)" "unprognostic (1.55e-2)" "unprognostic (2.66e-1)" "unprognostic (2.36e-1)" "unprognostic (9.61e-2)" "unprognostic (1.24e-1)" "unprognostic (2.02e-3)" "unprognostic (1.01e-1)" "unprognostic (1.32e-2)" "unprognostic (3.07e-1)" "unprognostic (1.75e-1)" "unprognostic (4.52e-2)" "unprognostic (2.69e-1)" 1.0 1.5 1.2 0.3 1.2 0.5 1.4 1.7 4.0 1.2 8.8 1.0 0.6 2.0 3.7 1.3 10.0 1.3 2.3 1.1 3.1 2.7 1.8 2.4 0.3 5.5 4.3 1.6 0.9 3.9 2.5 0.1 2.5 2.0 0.6 11.8 2.4 1.3 1.7 0.9 0.6 0.6 2.7 1.0 1.3 3.8 2.3 0.6 4.0 3.2 0.3 0.7 0.7 2.6 0.7 2.1 0.6 0.1 1.0 0.7 0.0 0.4 0.1 1.1 1.2 0.0 1.0 0.2 1.8 0.3 0.4 0.5 0.0 1.0 0.8 0.7 0.3 0.9 0.4 0.0 0.0 0.1 0.0 0.3 0.5 0.9 0.2 6.8 0.1 0.7 0.2 0.3 1.5 0.0 1.0 0.8 0.3 0.0 0.3 0.0 0.0 0.1 1.5 0.0 1.2 0.6 0.1 0.0 0.6 0.1 0.7 0.3 0.5 1.0 0.5 0.2 0.1 0.1 0.0 0.0 0.9 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.3 0.0 1.2 1.2 1.7 4.0 1.1 3.1 5.5 4.3 2.5 2.7 2.3 2.6 3.3 9.6 2.8 85.5 1.7 1.8 2.6 2.9 7.4 1.5 3.1 3.0 8.2 1.5 11.5 5.5 4.2 1.2 0.9 0.4 5.9 1.1 35.8 24.3 2.1 2.3 0.0 4.6 133.8 1.7 0.6 4.8 4.6 0.9 0.0 6.0 3.3 2.4 0.5 1.7 95.8 1.3 2.0 1.6 1.7 14.9 6.2 1.3 0.0 46.9 0.1 6.7 2.1 117.1 102.6 0.6 0.3 7.2 2.5 1.0 0.5 3.5 77.2 22.4 0.0 3.8 3.8 8.5 1.6 4.1 0.6 0.3 1.6 3.3 0.8 0.6 CASD1 "C7orf12, FLJ21213, FLJ21879" ENSG00000127995 "CAS1 domain containing 1" Q96PB1 7 94509219-94557019 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 93.7;Inhibitory neurons: 108.5;Oligodendrocyte precursor cells: 122.6;Oligodendrocytes: 170.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044404 Uncertain Approved Nucleoplasm Yes No "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA044404: AB_10964353" "unprognostic (4.02e-2)" "unprognostic (4.16e-2)" "unprognostic (1.43e-1)" "unprognostic (1.82e-1)" "unprognostic (7.04e-2)" "unprognostic (7.90e-2)" "unprognostic (3.66e-2)" "unprognostic (2.18e-2)" "unprognostic (9.83e-2)" "unprognostic (4.74e-2)" "unprognostic (4.95e-3)" "unprognostic (2.16e-2)" "unprognostic (5.24e-2)" "unprognostic (4.01e-3)" "unprognostic (1.93e-1)" "unprognostic (7.07e-2)" "unprognostic (2.59e-3)" 11.1 25.3 11.4 9.6 14.0 6.0 15.7 11.1 12.9 11.3 4.8 16.5 6.5 14.1 14.6 6.3 11.0 10.0 17.1 14.9 17.4 12.4 9.0 11.3 12.5 8.8 10.7 16.4 9.8 13.8 8.7 12.3 12.9 13.9 19.3 22.1 20.3 9.4 14.1 3.8 6.1 11.0 11.3 10.6 7.3 13.1 14.6 11.2 16.0 19.6 10.8 9.1 4.3 14.0 5.5 10.4 34.7 12.9 10.4 12.3 5.9 7.2 12.8 7.9 10.2 6.5 13.2 13.9 18.5 9.8 14.1 3.0 8.8 2.5 15.4 22.2 7.1 12.3 8.5 11.9 8.8 20.5 0.0 11.4 9.2 7.2 10.3 15.4 12.6 16.0 6.7 29.3 19.6 8.0 28.5 11.6 17.7 7.7 8.2 19.3 28.0 10.8 15.9 14.9 13.1 44.5 11.4 20.7 7.4 24.9 5.4 12.8 6.7 19.6 15.5 16.2 10.6 28.0 28.1 28.5 10.7 4.7 12.9 0.0 0.2 0.0 0.6 0.2 1.6 0.6 0.9 0.8 0.4 0.5 0.9 0.7 0.0 0.6 0.2 0.3 0.6 0.2 11.4 14.0 11.1 12.9 14.9 17.4 8.8 10.7 12.9 11.3 14.6 14.0 26.2 28.9 26.3 76.0 15.4 4.6 5.8 5.8 4.0 56.4 14.4 12.8 21.1 17.2 12.8 20.2 18.8 14.2 14.6 29.7 3.9 5.1 3.4 18.0 13.1 16.4 7.2 4.6 93.7 5.6 5.7 14.6 5.1 9.9 10.2 23.7 16.1 13.3 8.8 67.3 108.5 30.2 2.0 9.8 5.5 7.0 11.5 10.8 24.9 61.8 7.1 23.3 10.3 122.6 170.3 6.8 11.8 9.8 9.2 10.0 0.6 10.8 18.1 31.4 19.7 41.2 12.2 9.6 12.8 4.7 4.5 16.8 12.2 25.8 19.5 4.5 CAVIN2 "cavin-2, PS-p68, SDPR, SDR" ENSG00000168497 "Caveolae associated protein 2" O95810 2 191834310-191847088 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Adipocytes: 1296.7;Alveolar cells type 1: 413.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "basophil: 49.0;neutrophil: 24.3" "Lineage enriched" "Detected in many" 16 "granulocytes: 49.0" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 162.3;HEL: 119.8;HUVEC TERT2: 362.3;LHCN-M2: 561.1;TIME: 148.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA039325, HPA062122" Enhanced Enhanced "Plasma membrane,Cytosol" Yes No 88000000 "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA039325: AB_10805473, HPA062122: AB_2684688" "unprognostic (6.85e-3)" "unprognostic (1.37e-1)" "unprognostic (1.24e-1)" "unprognostic (4.47e-2)" "unprognostic (2.83e-1)" "unprognostic (1.46e-1)" "unprognostic (3.19e-2)" "unprognostic (6.14e-2)" "unprognostic (8.50e-2)" "unprognostic (1.38e-1)" "unprognostic (4.83e-2)" "unprognostic (2.90e-1)" "prognostic favorable (8.45e-5)" "prognostic unfavorable (3.69e-4)" "unprognostic (1.03e-1)" "unprognostic (1.33e-1)" "unprognostic (4.39e-3)" 164.9 25.1 17.9 13.0 20.1 6.5 60.9 16.9 20.2 56.8 13.1 69.4 11.5 38.9 13.2 48.2 53.9 51.8 96.7 15.1 16.5 25.9 31.2 93.9 15.3 19.5 17.3 53.0 22.5 12.9 7.1 34.0 19.5 30.2 24.9 1.1 7.1 30.0 32.3 6.9 21.1 58.1 15.9 111.9 15.0 4.3 22.3 4.1 78.3 59.9 5.6 42.7 19.5 17.0 0.0 20.2 6.8 0.1 1.0 3.4 0.1 4.1 3.5 0.8 1.5 0.0 0.0 0.1 24.8 162.3 0.0 3.4 0.0 31.8 2.3 0.1 0.0 119.8 1.4 45.6 43.6 0.0 0.0 8.4 20.5 3.4 9.6 2.2 362.3 0.0 43.9 0.0 561.1 0.0 0.0 0.1 0.1 0.0 1.0 0.0 32.3 0.2 41.7 0.0 0.0 0.1 0.0 0.0 0.0 9.1 0.0 0.1 148.9 0.0 12.4 7.4 0.0 0.0 0.0 0.1 0.0 1.0 0.0 49.0 2.4 1.2 0.2 0.8 0.3 0.1 0.0 0.0 2.3 0.3 0.2 0.0 24.3 1.3 1.5 3.1 0.5 121.3 17.9 20.1 16.9 20.2 15.1 16.5 19.5 17.3 19.5 15.9 22.3 17.0 1296.7 413.5 76.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 1.7 15.6 0.0 0.0 81.7 0.0 0.0 0.2 2.6 0.0 5.9 1.6 0.0 0.4 5.4 164.5 0.0 0.0 0.0 0.2 0.2 15.0 0.0 0.6 185.4 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.7 29.2 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.1 1.5 16.4 0.0 0.0 CBR3 SDR21C2 ENSG00000159231 "Carbonyl reductase 3" O75828 21 36135079-36146562 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 56.3;salivary gland: 41.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 102.5;Basal squamous epithelial cells: 107.0;Peritubular cells: 75.6;Squamous epithelial cells: 230.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 9 "B-cells: 23.9;NK-cells: 11.5;T-cells: 33.7" "Cell line enhanced" "Detected in many" "RPMI-8226: 64.9" "Region enhanced" "Detected in all" "basal ganglia: 48.6" "Low region specificity" "Detected in many" HPA018434 Uncertain Supported Nucleoplasm,Cytosol Yes NA 2800000 "Cluster 30: Non-specific - Translation" "Cluster 27: Brain & Skin - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "HPA018434: AB_1846110" "unprognostic (3.64e-3)" "unprognostic (2.32e-2)" "unprognostic (1.48e-1)" "unprognostic (1.46e-1)" "unprognostic (2.16e-1)" "unprognostic (1.18e-3)" "unprognostic (1.22e-1)" "unprognostic (2.22e-2)" "unprognostic (6.12e-2)" "unprognostic (2.98e-2)" "unprognostic (3.75e-1)" "unprognostic (9.10e-2)" "prognostic unfavorable (5.95e-6)" "unprognostic (3.13e-1)" "unprognostic (1.80e-1)" "unprognostic (3.99e-3)" "unprognostic (1.94e-1)" 17.3 2.3 12.8 4.0 14.7 1.4 15.3 13.9 19.8 12.4 11.2 7.8 3.0 7.5 11.0 56.3 8.8 6.5 6.1 13.2 12.4 2.7 0.8 4.6 2.9 12.8 12.1 11.2 1.6 0.6 2.4 2.9 12.3 9.9 3.6 0.6 41.4 5.1 3.1 21.6 5.4 6.1 12.0 3.1 5.2 3.1 12.2 2.0 4.6 7.8 7.6 11.6 16.8 12.4 33.5 9.5 4.0 8.2 31.0 47.8 5.9 35.4 42.4 40.6 32.1 0.4 6.9 0.0 10.2 37.2 13.7 15.0 5.5 7.2 16.2 45.3 17.2 1.4 10.0 0.3 2.6 0.1 0.1 6.8 0.8 28.1 3.6 19.1 24.9 3.7 0.0 0.3 12.1 25.4 3.1 14.7 3.2 10.3 41.5 6.7 7.6 64.9 13.7 14.2 2.1 2.9 27.3 32.6 53.3 2.2 9.8 3.9 17.1 25.7 2.2 28.8 35.0 1.5 0.6 0.0 26.9 0.9 47.3 0.0 0.6 0.1 2.2 0.5 3.0 23.6 25.1 7.7 2.4 23.9 33.7 23.5 0.9 11.5 1.0 0.7 10.9 11.5 12.8 14.7 13.9 19.8 13.2 12.4 12.8 12.1 12.3 12.0 12.2 12.4 41.7 0.0 3.2 6.8 5.2 71.0 22.1 102.5 107.0 0.8 23.1 38.6 0.2 2.8 23.0 0.0 0.0 1.2 2.9 1.9 9.8 4.7 0.7 13.1 7.5 26.5 0.0 1.7 3.9 0.7 0.3 53.4 7.7 14.7 5.7 1.1 14.3 0.3 8.4 0.0 5.5 12.6 69.2 3.8 41.3 4.0 67.7 5.8 65.8 2.8 20.9 1.9 0.0 1.5 0.5 2.6 1.7 75.6 1.4 43.4 1.3 0.2 13.1 0.6 0.0 21.4 19.7 0.4 0.2 230.4 46.7 0.3 7.0 1.0 8.1 21.1 CCDC137 MGC16597 ENSG00000185298 "Coiled-coil domain containing 137" Q6PK04 17 81666737-81673904 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052637, HPA053914" Uncertain Enhanced "Nucleoli,Mitotic chromosome" Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 27: Brain & Skin - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Mitotic chromosome" "HPA052637: AB_2681894, HPA053914: AB_2682306" "unprognostic (3.04e-1)" "unprognostic (5.82e-2)" "unprognostic (1.76e-1)" "unprognostic (3.07e-2)" "unprognostic (1.68e-2)" "unprognostic (2.24e-1)" "prognostic unfavorable (1.35e-7)" "prognostic unfavorable (8.32e-4)" "unprognostic (2.21e-2)" "unprognostic (8.33e-3)" "unprognostic (1.26e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (1.16e-7)" "unprognostic (4.26e-2)" "unprognostic (2.01e-1)" "unprognostic (3.93e-1)" "unprognostic (1.39e-1)" 8.2 9.5 13.8 12.3 13.7 17.7 7.6 13.5 17.5 10.7 14.2 9.3 11.4 7.5 5.5 23.1 7.8 6.1 6.5 13.7 13.8 10.2 10.8 7.7 16.3 14.4 14.3 6.7 8.2 7.0 6.2 7.7 14.7 11.7 5.8 2.8 9.9 6.4 7.7 22.8 10.7 6.0 13.4 15.6 8.8 10.4 14.5 11.8 7.8 4.5 11.5 9.8 13.8 14.3 38.0 62.8 21.5 35.3 13.9 13.1 35.2 41.6 19.7 53.0 30.6 55.1 22.8 33.8 22.4 21.2 36.6 47.9 34.5 43.8 30.6 19.4 51.7 51.6 30.1 48.0 20.7 46.6 37.5 19.8 26.3 47.6 26.3 14.6 37.4 41.1 53.3 19.1 28.3 34.5 45.7 56.6 46.9 32.9 59.8 55.4 34.6 24.1 19.8 29.6 45.1 57.7 41.1 87.8 37.1 28.9 58.8 48.3 27.8 82.0 53.5 34.9 65.9 53.1 28.7 36.8 30.8 42.9 48.8 2.2 7.7 11.7 11.5 9.6 6.3 10.4 8.7 8.8 7.5 13.2 9.2 8.8 3.3 13.1 11.9 12.9 9.8 5.9 13.8 13.7 13.5 17.5 13.7 13.8 14.4 14.3 14.7 13.4 14.5 14.3 17.9 22.4 17.0 5.9 29.8 31.7 22.8 19.7 74.6 6.8 17.4 13.7 6.7 15.7 20.9 12.9 2.1 25.7 31.5 19.7 19.6 25.2 1.7 26.5 32.9 20.3 7.2 37.5 4.5 21.4 41.0 16.5 29.0 29.4 19.6 28.1 15.4 11.8 24.3 18.5 4.6 17.0 14.2 12.9 11.5 1.7 13.7 16.8 16.0 4.7 24.2 13.8 37.0 4.0 5.0 35.2 16.0 13.5 25.7 40.0 12.4 15.9 21.6 9.1 6.6 13.7 22.3 30.8 44.9 57.0 34.4 20.8 29.7 22.8 22.4 24.2 CCDC171 "bA536D16.1, bA778P13.1, C9orf93, Em:AL513423.1, FLJ39267, FLJ46740" ENSG00000164989 "Coiled-coil domain containing 171" Q6TFL3 9 15553043-16061663 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 11.3" "Cell type enhanced" "Detected in many" "Early spermatids: 194.5;Excitatory neurons: 92.4;Inhibitory neurons: 70.6;Late spermatids: 172.4;Spermatocytes: 148.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 2.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Daudi: 7.5;HEL: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019803, HPA019806, HPA024133" Uncertain Approved Nucleoplasm,Nucleoli Yes No "Cluster 41: Basophils - Cellular respiration" "Cluster 21: Non-specific - Transcription" "Cluster 36: HEL - Hemostasis" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Nucleoli "HPA019803: AB_1845846, HPA019806: AB_1845847, HPA024133: AB_1845848" "unprognostic (1.35e-2)" "unprognostic (2.03e-4)" "unprognostic (7.22e-3)" "unprognostic (1.16e-1)" "unprognostic (1.43e-1)" "unprognostic (1.09e-1)" "unprognostic (1.51e-2)" "unprognostic (2.05e-2)" "unprognostic (2.18e-1)" "unprognostic (6.76e-3)" "unprognostic (5.37e-2)" "unprognostic (1.28e-1)" "unprognostic (2.92e-3)" "unprognostic (7.80e-2)" "unprognostic (4.90e-2)" "unprognostic (1.15e-1)" "unprognostic (6.91e-3)" 0.8 1.1 2.3 0.7 2.8 2.1 1.6 3.7 3.2 1.4 0.0 0.9 0.8 5.8 1.1 1.0 2.0 1.5 1.0 2.5 0.3 1.2 0.4 1.1 1.1 1.5 0.3 2.9 1.3 1.4 1.1 0.9 2.0 1.1 1.1 5.5 0.8 1.2 0.8 2.4 1.0 3.3 0.2 0.6 1.4 11.3 0.5 4.8 2.0 1.1 1.0 0.8 0.9 3.3 1.4 0.7 1.6 1.6 0.9 1.9 1.0 1.0 0.8 1.0 1.1 0.4 0.6 7.5 0.5 0.6 1.9 0.3 0.7 1.0 1.1 1.6 0.7 11.7 1.2 1.0 1.3 1.6 1.4 1.1 1.9 0.8 1.5 0.8 0.5 4.1 0.3 2.0 1.2 0.5 3.3 1.5 1.3 0.6 1.6 3.8 1.2 0.2 0.7 1.1 2.3 1.1 2.1 0.7 2.8 1.3 0.9 1.1 0.8 2.1 1.2 0.6 0.7 1.1 1.4 4.8 0.9 1.0 1.5 2.4 0.2 0.0 0.2 0.2 0.6 0.2 0.2 0.2 0.2 0.6 0.1 0.2 0.1 0.1 0.1 0.2 0.2 0.0 2.3 2.8 3.7 3.2 2.5 0.3 1.5 0.3 2.0 0.2 0.5 3.3 4.4 0.0 7.5 56.8 2.6 2.8 5.8 1.8 7.4 27.7 5.0 8.0 8.5 0.0 5.9 3.7 16.7 6.7 1.4 3.6 5.9 2.9 194.5 24.3 7.8 3.8 1.2 3.8 92.4 3.5 4.1 5.7 8.2 12.9 1.3 7.6 3.3 0.8 1.9 10.1 70.6 3.5 6.1 1.0 1.1 172.4 5.9 2.1 0.0 16.9 1.6 12.5 5.2 54.8 63.1 2.5 1.0 6.0 1.9 0.8 2.8 2.1 12.0 44.0 13.1 11.6 5.7 148.2 40.6 5.4 3.3 5.6 3.6 10.7 4.9 3.7 CCDC66 DKFZp686C0433 ENSG00000180376 "Coiled-coil domain containing 66" A2RUB6 3 56557161-56621837 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 202.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044185, HPA051937" Approved Supported "Cell Junctions,Midbody ring,Centriolar satellite,Cytosol" Yes No "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 52: Non-specific - Transcription" "Centriolar satellite" "Cell Junctions, Midbody ring, Cytosol" "HPA044185: AB_10965852, HPA051937: " "unprognostic (2.28e-2)" "unprognostic (7.74e-2)" "unprognostic (7.37e-2)" "unprognostic (2.90e-1)" "unprognostic (5.28e-2)" "unprognostic (1.72e-2)" "unprognostic (7.26e-3)" "unprognostic (1.68e-3)" "unprognostic (2.05e-2)" "unprognostic (1.27e-1)" "unprognostic (3.05e-3)" "unprognostic (5.48e-3)" "unprognostic (6.85e-3)" "unprognostic (1.81e-1)" "unprognostic (6.57e-2)" "unprognostic (3.24e-1)" "unprognostic (6.81e-3)" 2.7 3.1 3.8 3.6 3.7 3.0 5.2 3.7 4.3 4.8 4.2 4.0 3.0 4.1 5.3 2.5 5.7 3.4 2.9 3.7 4.2 4.1 2.0 3.6 4.9 3.8 3.7 6.0 3.3 5.4 4.5 3.3 3.9 4.0 4.1 7.8 3.3 3.6 4.5 2.5 2.8 4.9 3.8 4.3 3.2 3.7 3.7 5.1 4.9 2.6 4.9 3.7 3.1 3.8 5.6 2.0 5.8 3.7 8.9 5.2 4.6 6.8 6.4 9.1 7.8 4.3 4.3 15.6 1.6 3.8 5.8 2.8 3.4 6.5 10.1 5.6 4.0 9.5 9.0 4.6 6.2 12.8 3.3 4.9 8.8 7.7 5.1 8.0 6.0 7.7 9.3 2.4 7.2 4.7 10.0 7.5 9.7 4.8 7.5 3.4 5.2 8.6 5.3 1.9 2.2 4.2 8.7 5.5 5.2 4.9 1.9 5.2 3.1 6.6 5.2 6.3 9.9 4.7 5.3 8.0 4.9 14.3 5.5 10.0 1.5 3.5 4.1 2.0 5.4 2.7 7.0 5.0 1.1 1.6 8.0 5.8 0.3 5.1 2.4 1.0 14.8 2.6 3.8 3.7 3.7 4.3 3.7 4.2 3.8 3.7 3.9 3.8 3.7 3.8 39.7 22.4 22.6 42.7 41.3 28.2 20.1 30.5 15.9 68.5 18.5 21.0 30.5 30.0 29.0 22.0 108.4 23.0 51.5 7.7 29.4 23.7 202.5 58.1 33.5 28.8 21.0 40.8 93.2 10.5 14.6 29.9 18.8 13.9 34.2 38.3 37.9 8.5 18.4 52.2 95.8 11.4 22.4 35.8 27.9 109.6 54.0 20.7 26.6 51.5 56.1 36.8 105.0 70.9 96.7 14.1 9.8 47.8 28.1 25.5 11.5 20.3 51.5 111.5 32.9 38.6 30.9 55.8 46.8 12.1 29.5 16.4 51.7 33.6 14.5 11.4 CCDC7 "BIOT2, C10orf68, FLJ13031, FLJ32762" ENSG00000216937 "Coiled-coil domain containing 7" Q96M83 10 32446140-32882874 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 17 "brain: 28.1;testis: 78.0" "Cell type enhanced" "Detected in many" "Early spermatids: 489.6;Late spermatids: 914.3;Oligodendrocytes: 161.0;Spermatocytes: 176.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA075536 Approved "Nucleoli,Mitotic spindle,Cytosol" Yes No "Cluster 20: T-cells - T-cell receptor" "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" Nucleoli "Mitotic spindle, Cytosol" "HPA075536: AB_2686755" "unprognostic (3.43e-3)" "unprognostic (4.75e-2)" "unprognostic (1.85e-1)" "unprognostic (1.01e-2)" "unprognostic (2.69e-2)" "unprognostic (3.75e-3)" "unprognostic (2.65e-5)" "unprognostic (6.95e-2)" "unprognostic (7.57e-2)" "unprognostic (1.55e-1)" "unprognostic (2.44e-3)" "unprognostic (2.84e-2)" "unprognostic (2.95e-5)" "unprognostic (7.56e-2)" "unprognostic (1.92e-1)" "unprognostic (1.23e-1)" "unprognostic (3.71e-2)" 1.0 1.2 10.9 0.9 20.3 2.4 1.3 28.1 14.5 1.4 0.0 1.1 1.2 1.3 1.5 1.2 0.8 1.1 1.1 3.1 8.9 1.1 0.7 1.2 1.6 13.7 9.1 1.5 1.5 0.8 1.7 0.9 17.0 1.1 1.5 3.0 0.8 1.3 0.7 0.7 1.0 1.2 10.7 1.1 1.2 78.0 15.6 0.8 1.9 0.6 1.4 0.8 1.0 23.7 1.4 1.5 0.4 1.8 1.2 0.9 0.6 1.2 0.4 0.4 1.2 0.3 2.0 1.0 0.6 0.8 1.1 0.6 0.7 0.7 1.6 3.6 0.2 0.5 1.3 0.4 2.1 0.6 0.9 0.8 0.3 0.8 0.3 0.8 0.5 1.6 0.8 3.4 1.5 0.2 0.4 0.3 0.4 0.7 1.4 0.9 1.9 0.1 1.2 0.3 0.9 1.0 0.2 0.2 0.9 0.5 1.0 0.8 2.0 1.0 1.2 1.3 0.7 1.1 0.8 1.0 1.3 4.0 0.6 0.0 0.3 0.0 1.7 0.2 1.7 1.2 2.7 1.5 0.1 0.6 2.9 2.0 0.0 1.8 0.1 1.0 2.0 0.3 10.9 20.3 28.1 14.5 3.1 8.9 13.7 9.1 17.0 10.7 15.6 23.7 7.4 6.4 8.6 87.8 4.8 1.9 1.1 0.5 2.2 8.9 4.1 3.9 7.2 0.0 3.0 1.8 4.2 0.7 6.2 2.0 1.9 4.6 489.6 5.0 6.1 3.5 3.0 2.1 84.3 3.4 1.1 3.7 4.1 5.4 12.6 7.0 0.0 0.0 1.7 0.0 103.3 2.8 0.0 0.0 1.2 914.3 9.6 3.1 1.8 93.7 2.4 3.5 4.1 96.0 161.0 2.8 0.5 7.2 3.8 0.5 2.4 1.1 1.1 23.1 13.1 6.0 3.6 176.0 9.4 1.3 1.1 0.1 8.6 4.6 2.1 0.6 CCDC85C ENSG00000205476 "Coiled-coil domain containing 85C" A6NKD9 14 99500190-99604207 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 72.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 62.6;Rod photoreceptor cells: 51.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058346, HPA061922" Uncertain Approved "Nucleoplasm,Nucleoli rim,Nuclear bodies,Mitotic chromosome,Cell Junctions" Yes No "Cluster 20: T-cells - T-cell receptor" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" "Nucleoli rim, Cell Junctions" "Nucleoplasm, Nuclear bodies, Mitotic chromosome" "HPA058346: AB_2683686, HPA061922: " "unprognostic (7.17e-2)" "unprognostic (2.23e-2)" "unprognostic (3.64e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (5.70e-2)" "unprognostic (2.61e-1)" "unprognostic (1.68e-3)" "unprognostic (4.80e-2)" "unprognostic (1.45e-2)" "unprognostic (8.75e-2)" "unprognostic (3.30e-1)" "unprognostic (1.68e-3)" "prognostic favorable (2.60e-5)" "unprognostic (4.14e-2)" "unprognostic (1.95e-1)" "unprognostic (8.74e-3)" "unprognostic (9.81e-3)" 5.2 22.0 26.4 4.3 32.9 9.7 7.1 72.9 27.1 5.8 20.6 31.3 18.7 15.4 14.3 28.3 11.3 5.4 19.6 24.8 20.9 14.4 18.2 8.1 2.5 30.8 24.1 5.1 18.5 16.4 17.0 8.6 27.0 15.0 11.1 34.7 26.4 16.2 20.7 19.4 17.7 13.1 24.5 3.6 19.2 8.5 28.6 5.0 9.3 5.6 7.5 16.1 8.9 21.0 48.4 43.4 52.7 31.7 0.7 0.2 48.9 16.0 16.2 31.4 18.1 52.9 49.8 0.3 61.7 18.2 8.6 63.3 39.2 38.4 19.5 79.2 23.3 2.5 43.6 36.1 4.2 0.5 4.9 0.1 19.9 9.0 25.9 18.6 9.9 27.9 11.8 7.2 3.9 80.3 21.8 6.6 19.3 55.4 44.7 32.1 22.1 10.8 22.3 18.8 26.0 32.6 40.7 21.5 9.5 19.9 46.9 9.8 22.6 6.2 51.5 22.4 16.2 11.2 15.8 0.4 1.0 4.3 4.5 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.4 0.1 26.4 32.9 72.9 27.1 24.8 20.9 30.8 24.1 27.0 24.5 28.6 21.0 8.5 22.4 5.6 15.7 6.7 8.8 8.7 4.0 13.6 35.2 12.1 9.3 3.0 5.7 7.3 1.8 62.6 6.3 3.9 21.2 0.0 7.6 3.1 18.8 8.1 9.2 9.6 3.4 2.8 9.4 4.5 6.2 17.3 35.6 6.3 14.1 5.3 16.7 1.8 1.7 5.4 9.6 6.1 1.6 1.2 2.1 0.6 5.0 8.8 4.7 0.4 30.6 1.0 1.5 11.7 17.4 13.2 0.7 10.4 11.0 23.3 6.5 3.0 51.7 0.0 5.7 4.1 1.4 3.5 20.4 14.1 4.9 8.3 2.3 13.0 12.0 CCDC86 MGC2574 ENSG00000110104 "Coiled-coil domain containing 86" Q9H6F5 11 60842113-60851081 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "parathyroid gland: 377.6" "Cell type enhanced" "Detected in many" "Spermatocytes: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041117, HPA041540" Enhanced Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 25: RPMI-8226 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA041117: AB_10794984, HPA041540: AB_10794299" "unprognostic (2.93e-1)" "unprognostic (6.59e-2)" "unprognostic (2.38e-1)" "unprognostic (1.47e-3)" "unprognostic (3.64e-1)" "prognostic unfavorable (7.36e-5)" "prognostic unfavorable (1.71e-4)" "unprognostic (1.65e-3)" "unprognostic (9.52e-2)" "unprognostic (1.25e-2)" "unprognostic (6.12e-2)" "unprognostic (4.47e-1)" "unprognostic (3.76e-2)" "unprognostic (7.54e-3)" "unprognostic (2.90e-1)" "unprognostic (2.16e-1)" "unprognostic (6.25e-2)" 25.6 26.7 12.0 14.3 13.3 10.2 20.8 13.1 14.2 12.9 11.2 14.1 11.4 16.7 3.5 19.4 15.2 6.9 16.0 12.7 13.5 19.2 13.7 11.8 11.6 13.2 13.5 13.8 23.9 377.6 24.9 11.6 13.7 23.9 5.8 8.2 12.2 8.6 34.7 22.7 12.3 10.4 12.3 12.7 16.4 48.9 12.7 8.8 12.9 13.7 8.5 20.2 14.5 14.1 83.4 110.2 26.5 76.1 21.8 35.7 36.3 54.3 42.4 98.1 52.4 95.0 53.7 98.9 100.7 31.0 69.7 73.3 94.2 65.7 48.2 35.7 101.3 51.0 45.8 133.2 70.7 80.7 82.6 39.5 48.7 90.2 61.8 14.3 75.8 53.5 166.0 46.9 50.3 97.3 125.2 122.6 107.0 48.6 156.3 81.4 39.6 253.5 37.2 33.8 59.9 38.9 34.7 79.5 64.6 17.6 80.8 30.3 45.9 93.6 59.6 131.6 118.2 41.0 66.5 109.2 78.2 86.0 118.6 1.7 13.5 4.2 9.1 29.4 9.7 9.4 9.6 8.3 29.8 9.0 11.5 10.2 1.0 6.9 9.3 16.6 9.7 10.1 12.0 13.3 13.1 14.2 12.7 13.5 13.2 13.5 13.7 12.3 12.7 14.1 9.3 0.0 2.2 2.0 8.9 37.0 22.2 5.7 28.5 12.1 9.9 10.3 0.6 4.3 4.0 1.8 8.4 17.2 5.7 5.3 7.9 18.6 25.6 6.8 9.4 12.7 7.2 8.8 2.0 12.2 20.4 10.2 9.7 7.7 5.1 7.9 3.6 3.1 18.4 3.3 1.7 5.7 6.1 2.5 16.5 15.0 11.5 7.3 16.0 1.0 5.3 3.9 4.1 1.0 1.3 19.2 3.6 6.0 8.6 24.0 4.4 7.3 1.3 8.3 19.7 10.7 19.1 74.6 18.8 21.2 31.0 8.2 7.0 12.5 11.3 18.8 CCNA2 "CCN1, CCNA" ENSG00000145386 "Cyclin A2" P20248 4 121816444-121823883 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.6;lymphoid tissue: 46.9;retina: 31.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 47.9;Erythroid cells: 102.1;Extravillous trophoblasts: 92.8;Plasma cells: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 3.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 3.4;white matter: 7.6" "CAB000114, HPA020626" Enhanced Enhanced Nucleoplasm,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "CAB000114: AB_563675, HPA020626: AB_1847376" "unprognostic (4.02e-2)" "unprognostic (1.93e-1)" "unprognostic (7.66e-3)" "prognostic unfavorable (8.78e-4)" "unprognostic (1.25e-1)" "unprognostic (1.67e-2)" "prognostic unfavorable (9.17e-5)" "prognostic unfavorable (4.27e-4)" "unprognostic (3.92e-3)" "unprognostic (2.65e-2)" "prognostic unfavorable (4.43e-6)" "unprognostic (8.38e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.65e-1)" "unprognostic (1.82e-1)" "unprognostic (6.07e-2)" "unprognostic (1.59e-1)" 1.5 1.2 2.5 11.4 2.5 38.6 2.5 3.5 4.7 4.3 2.5 9.8 10.1 2.5 0.6 8.4 2.2 1.8 1.3 2.3 2.4 1.5 1.6 1.8 25.0 2.8 2.7 3.8 0.8 0.6 2.7 10.5 2.6 1.9 11.5 31.7 1.8 0.8 0.7 6.7 9.9 4.0 2.6 4.6 4.4 6.2 2.6 46.9 1.2 0.5 24.4 2.9 3.9 3.5 177.1 45.3 120.5 51.8 6.4 16.3 98.8 119.7 52.8 156.7 115.6 99.4 106.5 161.2 31.7 63.8 55.0 58.0 154.2 71.1 128.0 77.8 70.8 129.7 56.0 96.9 1.5 197.0 88.0 4.2 5.3 65.1 38.7 24.7 95.4 84.3 187.9 156.9 126.1 63.8 251.8 113.1 95.5 109.9 49.8 114.1 233.5 78.2 44.8 34.6 51.0 53.8 63.1 76.0 32.4 89.8 63.7 81.9 56.5 72.7 109.3 77.4 115.9 98.0 112.3 181.9 41.5 197.6 82.4 0.0 0.1 0.3 0.1 0.0 0.0 0.1 0.9 0.6 0.4 0.0 0.0 0.2 0.1 0.8 0.1 0.0 3.1 0.9 2.5 2.5 3.5 4.7 2.3 2.4 2.8 2.7 2.6 2.6 2.6 3.5 0.8 0.0 1.1 1.6 5.7 2.8 1.5 5.5 1.8 2.9 1.9 1.8 0.8 0.0 1.6 0.0 12.5 47.9 1.9 4.9 0.0 0.7 9.6 0.6 2.7 3.3 1.2 102.1 3.3 0.2 92.8 6.3 9.2 2.1 0.0 18.1 4.2 0.9 25.3 0.0 4.1 7.7 8.2 6.9 3.6 2.1 0.9 3.6 1.8 2.8 0.2 1.2 0.0 4.5 5.2 0.5 3.1 1.2 35.5 3.3 1.8 0.2 2.5 14.2 0.0 0.9 6.0 10.3 17.7 24.0 1.3 8.5 6.3 1.4 19.9 2.1 CCNB1 CCNB ENSG00000134057 "Cyclin B1" P14635 5 69167135-69178245 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 52.9;lymphoid tissue: 76.2" "Cell type enriched" "Detected in many" 6 "Extravillous trophoblasts: 723.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 3.0;white matter: 8.3" "Not detected" "Not detected" "CAB000115, CAB003804, HPA030741, HPA061448" Enhanced Enhanced Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "CAB000115: , CAB003804: AB_562272, HPA030741: AB_2673586, HPA061448: AB_2684522" "unprognostic (4.12e-2)" "unprognostic (2.75e-2)" "unprognostic (1.91e-3)" "unprognostic (4.08e-3)" "unprognostic (2.78e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.54e-7)" "prognostic unfavorable (3.38e-4)" "unprognostic (1.43e-2)" "unprognostic (1.63e-2)" "unprognostic (2.49e-3)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.11e-16)" "unprognostic (2.44e-1)" "unprognostic (3.73e-1)" "unprognostic (1.44e-1)" "unprognostic (5.15e-3)" 4.0 5.1 4.0 26.0 3.9 52.9 10.0 6.0 4.9 6.3 2.8 22.2 20.9 7.7 5.4 36.0 8.2 4.0 3.0 3.8 4.0 4.8 4.3 3.9 54.5 6.2 4.4 5.0 4.2 5.8 2.6 20.8 6.5 3.8 29.5 5.7 6.5 3.9 3.4 14.5 19.5 14.4 3.5 11.1 10.8 32.9 5.2 76.2 9.3 2.0 67.0 8.4 10.4 4.0 466.0 317.1 423.5 377.1 22.2 37.1 980.2 201.3 150.8 521.3 437.0 471.2 423.9 285.2 239.1 187.6 594.2 284.2 432.4 442.8 577.2 281.4 217.2 181.6 243.2 323.2 6.8 160.5 197.7 16.6 27.7 300.5 207.2 47.7 282.8 274.2 223.5 217.9 430.2 441.4 220.5 184.7 236.7 153.3 199.3 228.4 305.2 288.2 192.6 168.2 212.7 133.5 347.7 160.3 141.9 236.4 306.4 162.5 119.8 114.4 368.5 207.6 510.2 109.2 216.6 399.8 158.8 271.9 358.6 3.1 2.0 1.5 3.2 5.1 4.5 15.4 8.3 7.4 6.0 11.1 2.7 2.6 1.3 8.2 2.4 5.0 17.6 6.2 4.0 3.9 6.0 4.9 3.8 4.0 6.2 4.4 6.5 3.5 5.2 4.0 4.0 0.0 0.5 2.0 11.8 11.5 7.2 32.1 4.6 4.8 9.8 12.3 1.9 1.5 8.8 5.5 2.1 108.2 8.3 9.5 1.9 6.5 110.2 15.2 7.4 6.6 1.2 76.2 2.7 1.4 723.1 18.3 21.4 13.0 2.5 63.0 8.9 3.2 60.2 0.0 2.1 13.8 73.2 12.0 7.2 17.8 3.1 9.7 3.6 1.0 2.7 3.9 2.1 0.5 1.0 2.4 1.5 2.6 24.1 4.5 2.5 5.6 13.1 4.1 6.6 4.9 18.5 74.3 62.2 37.4 7.2 41.5 8.0 11.8 33.4 7.8 CCNB2 HsT17299 ENSG00000157456 "Cyclin B2" O95067 15 59105126-59125045 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 74.6;lymphoid tissue: 73.1;testis: 69.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 67.9;Early spermatids: 228.5;Erythroid cells: 123.6;Extravillous trophoblasts: 128.3;Spermatocytes: 288.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 5 "T-reg: 22.7" "Lineage enriched" "Detected in many" 6 "T-cells: 22.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA008873, CAB009575" Enhanced Enhanced "Golgi apparatus,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Golgi apparatus" "CAB009575: AB_2072392, HPA008873: AB_1078604" "unprognostic (2.69e-2)" "unprognostic (2.25e-1)" "unprognostic (4.43e-2)" "unprognostic (1.96e-2)" "unprognostic (1.77e-1)" "unprognostic (4.65e-2)" "prognostic unfavorable (2.83e-4)" "prognostic unfavorable (4.63e-4)" "prognostic unfavorable (3.21e-5)" "unprognostic (1.09e-1)" "prognostic unfavorable (1.74e-5)" "unprognostic (4.48e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.96e-1)" "unprognostic (1.41e-1)" "unprognostic (3.98e-2)" "unprognostic (4.44e-1)" 1.0 1.1 0.4 12.2 1.1 74.6 2.9 0.7 0.7 2.9 1.1 14.3 14.1 2.6 0.3 16.1 1.1 1.9 0.7 0.6 0.7 1.1 1.4 2.2 33.0 1.3 1.0 0.8 0.7 0.2 0.3 11.4 1.0 1.6 16.8 0.3 2.8 0.4 0.7 9.4 12.0 6.4 0.7 7.1 5.6 69.4 1.1 73.1 1.0 0.4 43.7 3.6 5.6 2.2 132.5 112.1 188.6 47.1 8.5 16.6 97.5 104.8 69.9 165.2 135.6 187.8 81.1 122.1 75.4 71.8 97.2 160.1 181.4 92.6 157.8 124.1 92.4 153.1 127.3 108.1 2.5 118.1 98.6 6.3 12.6 71.4 91.9 32.7 114.1 147.0 163.1 194.5 128.2 96.5 137.9 177.2 138.6 58.5 65.2 157.5 260.0 124.4 53.3 91.9 115.2 75.9 148.9 80.2 97.3 147.9 139.4 120.4 58.5 81.6 134.4 90.5 210.5 84.2 133.2 213.8 53.6 267.1 117.9 0.0 0.1 0.7 0.1 0.0 0.3 2.1 4.6 5.0 3.0 1.7 0.0 0.1 0.8 3.6 0.1 0.1 22.7 2.1 0.4 1.1 0.7 0.7 0.6 0.7 1.3 1.0 1.0 0.7 1.1 2.2 0.3 0.0 0.6 0.0 6.8 4.8 2.8 11.5 1.8 0.2 2.5 3.3 0.5 0.0 3.2 0.0 0.0 67.9 1.6 4.1 0.0 0.7 228.5 5.3 3.1 3.9 3.0 123.6 0.7 0.2 128.3 7.2 7.1 5.9 0.0 29.9 6.1 1.1 29.9 0.0 0.8 10.1 20.3 10.6 3.3 53.5 4.4 7.9 0.0 0.0 2.4 0.2 1.0 0.0 1.4 0.4 1.9 1.9 18.7 2.3 2.1 0.0 1.8 0.3 0.0 1.0 5.7 288.7 32.1 20.3 6.1 16.3 4.4 4.1 23.4 5.0 CCND1 "BCL1, D11S287E, PRAD1, U21B31" ENSG00000110092 "Cyclin D1" P24385 11 69641156-69654474 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, Transcription, Transcription regulation" "Cyclin, Repressor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 499.7;Ductal cells: 504.0;Pancreatic endocrine cells: 622.1;Urothelial cells: 412.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-266/70: 874.2;WM-115: 1239.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000024, HPA027802" Uncertain Supported Nucleoplasm Yes No "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 18: Non-specific - Mitochondria" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "CAB000024: AB_563678, HPA027802: AB_2672390" "unprognostic (4.90e-2)" "unprognostic (1.54e-1)" "unprognostic (7.62e-2)" "unprognostic (1.39e-2)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.51e-4)" "unprognostic (1.38e-1)" "unprognostic (2.53e-2)" "unprognostic (9.46e-2)" "unprognostic (4.84e-3)" "prognostic unfavorable (1.96e-4)" "unprognostic (4.39e-2)" "unprognostic (2.61e-3)" "unprognostic (4.38e-3)" "unprognostic (1.16e-1)" "unprognostic (6.40e-3)" "unprognostic (2.57e-1)" 55.6 29.2 12.1 10.0 14.6 1.5 40.2 15.0 11.9 17.0 33.4 19.8 22.7 14.8 27.6 72.9 30.8 19.5 64.9 10.8 14.6 32.2 107.3 61.1 10.5 17.5 15.5 4.6 86.3 82.7 25.7 63.7 18.3 53.3 17.2 3.2 30.4 50.4 3.6 120.3 16.0 23.3 15.9 37.2 52.7 3.2 21.7 9.9 45.5 5.2 19.0 29.5 43.9 24.0 467.3 183.0 59.5 1.8 178.3 186.7 127.4 717.5 264.9 82.1 47.6 206.9 349.9 0.1 317.6 375.5 137.2 332.1 6.5 195.2 146.0 1.2 36.5 0.3 46.7 211.7 43.3 3.3 6.7 106.5 37.9 116.0 44.0 192.5 142.1 0.2 0.6 1.3 654.2 197.1 0.4 26.6 109.0 190.7 198.3 1.2 187.9 11.3 379.4 282.8 10.0 231.4 9.2 167.7 458.4 143.5 102.6 9.5 600.4 399.5 111.0 176.1 496.2 874.2 559.4 1.5 341.6 5.9 1239.0 0.2 0.0 0.0 0.2 0.0 0.0 0.9 0.1 0.0 1.1 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 12.1 14.6 15.0 11.9 10.8 14.6 17.5 15.5 18.3 15.9 21.7 24.0 84.6 182.7 115.6 0.3 8.3 202.5 234.7 499.7 133.1 2.3 163.4 140.0 80.0 92.9 271.6 125.0 2.1 10.9 2.4 44.8 31.3 504.0 0.4 104.2 23.5 141.0 56.5 2.5 0.5 142.6 1.2 67.6 127.4 199.5 29.1 0.0 98.2 165.2 75.0 0.0 2.2 42.6 75.3 18.8 61.9 2.0 4.1 23.6 51.6 17.8 2.4 79.1 0.0 49.8 0.3 622.1 118.0 57.6 0.5 262.0 19.4 57.1 85.9 3.1 131.5 13.0 184.8 0.5 23.4 292.3 351.1 2.5 8.8 3.4 82.2 412.6 CCND2 ENSG00000118971 "Cyclin D2" P30279 12 4269771-4305353 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 354.3;Granulosa cells: 438.5;Langerhans cells: 255.3;Plasma cells: 371.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 152.4;HBEC3-KT: 136.6;HDLM-2: 238.8;Karpas-707: 287.9;RH-30: 202.7;RPMI-8226: 114.2" "HPA049138, HPA054196" Approved Enhanced Nucleoplasm Yes Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA049138: AB_2680650, HPA054196: AB_2682412" "unprognostic (2.98e-3)" "unprognostic (1.15e-1)" "unprognostic (7.21e-2)" "unprognostic (1.65e-2)" "unprognostic (1.70e-2)" "unprognostic (4.82e-2)" "unprognostic (4.94e-2)" "unprognostic (2.01e-3)" "unprognostic (3.16e-2)" "unprognostic (1.66e-2)" "prognostic favorable (2.52e-4)" "unprognostic (1.75e-1)" "unprognostic (1.25e-1)" "unprognostic (8.23e-2)" "unprognostic (4.52e-1)" "prognostic favorable (9.76e-5)" "unprognostic (7.06e-2)" 20.0 52.6 5.4 8.7 12.9 20.3 13.0 0.0 13.5 26.9 0.0 40.8 17.4 26.1 7.5 12.2 22.1 2.7 51.9 14.4 1.1 9.7 1.9 17.2 5.3 9.6 0.2 14.2 24.5 9.9 23.5 12.9 2.7 20.7 10.4 0.7 10.8 9.1 1.8 12.6 25.9 9.8 7.8 19.7 12.7 4.0 0.0 3.2 20.3 0.0 5.1 26.5 19.9 4.5 0.0 0.0 152.4 0.0 10.1 0.4 0.0 0.0 0.0 0.0 0.0 62.8 0.0 0.0 0.4 0.0 0.0 16.2 0.1 136.6 0.0 238.8 2.5 0.7 0.0 0.0 0.0 57.0 12.6 23.8 2.4 0.0 97.0 0.0 0.0 0.8 17.0 287.9 6.8 0.0 0.0 52.8 50.8 0.0 0.0 0.0 202.7 114.2 0.0 8.1 0.0 0.0 0.0 0.0 0.0 89.6 0.0 0.0 4.2 0.0 39.3 0.0 0.0 1.4 60.7 0.0 0.0 32.3 0.0 6.6 0.4 4.7 11.1 0.0 17.1 3.1 16.3 13.8 0.4 1.7 10.4 12.1 1.1 9.4 0.0 1.1 13.6 6.8 5.4 12.9 0.0 13.5 14.4 1.1 9.6 0.2 2.7 7.8 0.0 4.5 23.9 60.9 46.6 10.1 82.9 106.8 23.9 73.4 174.2 7.6 3.4 41.8 354.3 2.8 37.4 12.9 0.0 4.0 128.7 37.5 0.0 3.1 0.8 3.3 110.8 35.7 64.8 37.2 54.1 68.3 2.7 123.6 4.6 3.6 55.8 438.5 19.6 2.2 13.0 3.3 55.2 147.7 12.2 11.9 255.3 3.3 52.5 39.3 39.2 19.7 9.8 170.0 89.6 55.3 4.0 20.7 49.4 124.1 371.2 35.8 34.4 1.4 10.3 6.5 26.3 21.4 112.6 0.8 5.1 50.9 39.6 6.3 122.6 41.5 159.7 8.4 CCNE1 CCNE ENSG00000105173 "Cyclin E1" P24864 19 29811991-29824312 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.8;placenta: 30.8" "Cell type enriched" "Detected in many" 14 "Extravillous trophoblasts: 1756.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "BEWO: 293.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000308, CAB016682, HPA018169" Approved Enhanced Nucleoplasm Yes Yes "Cluster 43: B-cells - Humoral immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "CAB000308: , CAB016682: AB_1614564, HPA018169: AB_1847384" "unprognostic (2.90e-3)" "unprognostic (1.33e-2)" "unprognostic (1.47e-3)" "prognostic unfavorable (6.35e-6)" "unprognostic (5.78e-2)" "unprognostic (4.77e-2)" "prognostic unfavorable (3.89e-5)" "unprognostic (1.26e-3)" "unprognostic (3.14e-3)" "prognostic unfavorable (2.97e-4)" "unprognostic (3.29e-2)" "unprognostic (7.07e-2)" "unprognostic (1.11e-16)" "unprognostic (5.61e-2)" "unprognostic (1.92e-1)" "unprognostic (6.63e-2)" "unprognostic (1.46e-1)" 1.2 5.7 1.9 4.3 2.1 35.8 0.8 2.8 2.7 1.0 0.9 3.9 3.0 1.4 0.6 4.4 0.9 1.0 2.3 2.0 2.5 1.0 0.7 1.1 6.1 2.0 2.1 0.8 1.8 2.8 0.9 30.8 2.0 1.0 4.7 2.0 1.5 1.4 2.1 4.1 2.5 2.2 1.7 4.2 2.1 12.1 2.5 4.5 1.6 1.8 7.8 3.0 1.8 2.3 15.6 31.8 24.3 34.0 5.2 6.0 293.1 24.7 5.3 10.8 13.2 33.0 31.2 13.3 55.9 11.1 14.0 4.9 28.8 12.8 15.2 41.9 17.7 11.2 30.0 34.5 4.1 44.0 28.7 6.2 7.1 14.8 1.9 3.4 13.3 13.2 45.6 5.8 16.8 24.4 24.5 13.0 40.1 36.2 7.2 36.2 28.6 10.1 8.4 24.6 20.5 17.4 35.4 42.7 3.9 35.4 9.5 32.7 8.0 25.0 92.8 14.9 16.9 24.1 18.2 91.6 13.8 5.6 13.7 0.0 0.0 0.0 0.1 0.5 0.3 0.6 0.1 0.0 0.4 0.0 0.0 0.2 0.4 0.0 0.5 0.0 0.3 0.1 1.9 2.1 2.8 2.7 2.0 2.5 2.0 2.1 2.0 1.7 2.5 2.3 3.1 0.0 0.6 0.7 4.8 4.8 1.5 0.3 2.2 2.9 8.2 11.3 3.1 0.0 1.4 0.0 0.0 122.4 3.7 3.5 0.0 0.4 14.6 7.5 4.1 1.9 3.0 30.7 2.9 0.7 1756.5 6.0 5.6 20.1 0.0 4.6 1.4 0.2 43.4 3.3 5.1 3.3 0.0 1.0 2.5 3.6 1.2 4.2 1.8 0.0 0.2 1.7 0.0 2.5 1.3 1.4 2.2 2.2 18.4 2.2 1.0 0.4 0.1 1.1 6.6 4.1 3.4 25.0 17.6 8.5 6.0 115.7 4.5 6.9 4.9 3.5 CCNI2 FLJ16793 ENSG00000205089 "Cyclin I family member 2" Q6ZMN8 5 132747426-132754403 "Predicted intracellular proteins" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.3;intestine: 3.6" "Cell type enhanced" "Detected in some" "Distal tubular cells: 3.9;Gastric mucus-secreting cells: 7.1;Intestinal goblet cells: 3.5;Muller glia cells: 4.9;Plasma cells: 4.8;Undifferentiated cells: 4.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 5.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "MOLT-4: 25.7" "Low region specificity" "Detected in all" HPA056288 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" Yes NA "Cluster 13: T-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA056288: AB_2683086" "unprognostic (3.84e-2)" "unprognostic (2.44e-3)" "prognostic favorable (8.21e-4)" "unprognostic (5.97e-2)" "unprognostic (3.39e-1)" "unprognostic (6.71e-3)" "unprognostic (1.21e-1)" "unprognostic (7.49e-2)" "unprognostic (3.03e-1)" "unprognostic (2.50e-1)" "unprognostic (1.96e-2)" "unprognostic (1.07e-1)" "unprognostic (2.62e-1)" "unprognostic (1.77e-1)" "unprognostic (4.95e-1)" "unprognostic (1.71e-7)" "unprognostic (1.58e-1)" 0.2 0.3 1.2 0.9 1.9 0.1 0.2 1.3 1.5 0.5 0.0 2.6 3.6 0.1 0.3 0.1 0.3 0.4 0.3 0.9 0.8 3.1 0.0 0.5 0.8 2.2 1.3 0.2 1.2 0.0 0.6 0.1 1.6 0.9 2.7 1.1 2.6 1.3 0.3 0.3 2.1 0.1 0.9 0.4 2.4 0.7 1.5 1.5 0.4 0.0 0.9 0.9 0.2 4.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 3.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 5.7 0.0 0.4 0.0 0.6 25.7 0.1 0.4 1.6 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 1.3 1.0 0.3 0.3 0.0 0.0 0.0 0.0 1.7 4.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.5 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.8 0.1 1.2 1.9 1.3 1.5 0.9 0.8 2.2 1.3 1.6 0.9 1.5 4.3 0.2 0.0 0.5 0.0 0.9 0.1 0.4 0.8 0.0 0.1 0.4 0.1 0.6 0.0 0.4 0.0 0.0 0.4 0.1 3.4 3.9 0.4 2.2 0.4 0.0 0.1 1.2 0.0 0.6 1.5 0.2 0.3 7.1 0.5 1.3 0.0 0.0 0.0 0.1 1.7 0.5 3.5 0.0 0.0 0.0 2.1 0.3 0.4 0.0 0.0 0.0 4.9 0.0 1.0 2.4 1.5 2.3 0.0 4.8 0.6 1.8 0.3 1.0 0.2 0.0 0.1 0.2 0.2 0.7 0.0 0.1 0.0 1.9 0.1 4.2 0.6 CCNQ "CycM, FAM58A" ENSG00000262919 "Cyclin Q" Q8N1B3 X 153587925-153600045 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 72.4;Extravillous trophoblasts: 98.6;Syncytiotrophoblasts: 120.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050137, HPA059843" Uncertain Approved Nucleoplasm,Cytosol Yes No "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Cytosol" "HPA050137: AB_2681029, HPA059843: AB_2684140" "unprognostic (3.94e-1)" "unprognostic (1.94e-2)" "unprognostic (7.36e-2)" "unprognostic (2.92e-1)" "unprognostic (5.08e-2)" "unprognostic (1.02e-2)" "unprognostic (1.47e-3)" "unprognostic (2.12e-1)" "unprognostic (8.50e-3)" "unprognostic (2.08e-2)" "unprognostic (1.57e-2)" "unprognostic (1.90e-1)" "unprognostic (1.20e-1)" "unprognostic (8.75e-2)" "unprognostic (2.31e-1)" "unprognostic (2.71e-2)" "unprognostic (5.25e-2)" 11.8 12.8 19.9 8.2 21.3 7.3 11.7 19.6 24.9 11.9 15.6 16.2 8.9 12.9 12.7 13.1 11.1 4.0 33.9 20.8 20.5 13.5 13.2 10.6 12.5 23.2 21.6 10.5 15.0 10.3 23.6 9.2 23.4 13.6 8.0 6.4 12.9 8.8 34.3 12.1 13.6 6.1 20.0 17.2 13.3 6.2 21.2 9.0 11.1 13.6 12.2 14.0 11.7 24.9 43.7 31.2 12.1 43.5 20.9 11.2 18.7 25.0 21.8 23.5 23.6 33.3 14.3 34.9 44.6 25.1 35.3 26.7 38.4 22.6 22.2 20.3 39.2 7.8 19.4 23.5 19.0 28.2 18.9 14.1 20.1 15.7 16.1 10.0 19.0 16.1 10.6 15.6 19.1 50.5 19.7 38.0 15.1 44.4 52.4 22.6 20.0 17.8 17.0 17.6 16.0 21.1 12.0 19.3 34.4 11.9 7.3 25.0 14.6 20.5 29.3 46.7 38.5 21.8 23.1 43.4 18.5 45.4 15.7 0.0 1.6 4.9 2.7 1.4 1.0 6.1 2.3 1.9 1.3 4.1 2.5 1.7 0.9 0.7 0.8 1.2 3.4 1.1 19.9 21.3 19.6 24.9 20.8 20.5 23.2 21.6 23.4 20.0 21.2 24.9 21.0 3.2 13.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 24.1 31.0 0.0 0.0 3.1 7.3 0.0 40.7 20.4 0.0 72.4 23.3 0.0 11.9 17.3 7.8 0.0 0.0 0.0 37.1 98.6 8.4 0.0 8.7 2.5 16.3 0.0 0.0 41.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 22.7 0.0 0.0 0.0 0.0 34.0 0.0 0.0 5.9 0.0 0.0 41.6 2.2 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 120.9 10.0 18.4 0.0 0.0 CCNYL1 FLJ40432 ENSG00000163249 "Cyclin Y like 1" Q8N7R7 2 207711540-207761839 "Predicted intracellular proteins" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 62.7;Paneth cells: 121.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 83.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046825 Approved Approved "Plasma membrane" Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 83: Testis - Spermatogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA046825: AB_10963934" "unprognostic (2.59e-2)" "unprognostic (1.23e-1)" "unprognostic (1.03e-2)" "unprognostic (1.20e-3)" "unprognostic (1.78e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-3)" "unprognostic (5.48e-2)" "unprognostic (1.65e-1)" "unprognostic (1.41e-2)" "unprognostic (7.12e-3)" "unprognostic (7.99e-2)" "unprognostic (3.92e-2)" "unprognostic (8.08e-2)" "unprognostic (7.91e-2)" "unprognostic (2.37e-2)" "unprognostic (1.96e-3)" 12.8 4.7 3.8 10.6 4.9 9.9 7.1 2.8 5.3 8.2 3.7 15.3 11.7 5.0 5.2 17.8 4.2 7.9 6.1 5.2 5.1 10.9 12.4 11.8 8.6 4.8 4.2 3.4 13.7 4.2 4.5 13.6 5.1 4.8 13.3 9.0 6.9 4.8 7.8 3.9 11.3 8.7 4.2 8.1 11.0 16.2 4.5 6.1 11.4 4.4 9.3 10.4 9.5 6.8 25.7 11.0 14.5 20.4 18.6 21.2 83.3 15.6 25.8 15.7 17.7 51.1 23.7 9.9 14.2 28.6 38.5 17.4 17.7 29.4 15.2 3.7 13.5 13.3 12.8 41.6 18.7 11.9 15.2 10.7 12.0 20.0 20.9 13.8 52.5 11.5 6.8 9.4 21.9 13.6 10.5 11.2 28.1 10.3 12.2 9.4 12.4 8.0 16.2 19.5 3.5 10.8 18.5 8.0 23.5 33.6 7.2 31.5 27.3 17.7 16.6 23.2 10.5 5.6 8.4 13.4 18.5 13.5 15.4 0.7 1.1 0.5 0.3 0.6 0.4 0.3 0.5 0.5 0.5 1.1 0.4 0.8 1.3 0.6 0.5 0.5 0.4 0.3 3.8 4.9 2.8 5.3 5.2 5.1 4.8 4.2 5.1 4.2 4.5 6.8 31.8 3.2 19.1 10.1 14.1 12.2 13.8 7.6 5.7 6.2 10.0 10.0 9.0 2.8 8.5 23.9 10.4 12.6 13.2 62.7 1.9 5.8 13.7 13.6 7.7 17.0 9.6 6.5 34.1 14.7 42.9 11.4 25.0 20.4 5.7 5.8 23.9 12.5 16.2 5.0 11.6 13.1 8.2 17.5 29.9 10.9 2.8 18.7 8.8 7.5 20.8 10.2 7.2 14.6 28.7 13.9 121.3 3.8 7.7 16.1 10.1 12.6 6.3 12.3 0.0 16.0 10.4 23.9 9.5 7.6 10.5 7.7 10.9 4.3 17.0 18.0 CD180 "LY64, Ly78, RP105" ENSG00000134061 "CD180 molecule" Q99467 5 67179613-67196799 "CD markers, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.3" "Cell type enhanced" "Detected in some" "B-cells: 53.6;Hofbauer cells: 78.6;Kupffer cells: 23.5;Macrophages: 17.5;monocytes: 13.8;Plasma cells: 39.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 77.0;naive B-cell: 78.9" "Group enriched" "Detected in many" 25 "B-cells: 78.9;dendritic cells: 23.5;monocytes: 34.5" "Group enriched" "Detected in some" 10 "Daudi: 45.2;Karpas-707: 41.1;U-266/70: 33.1;U-266/84: 49.0;U-698: 12.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003740 Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Mitotic spindle" Yes NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Nucleoplasm, Nucleoli, Mitotic spindle" "HPA003740: AB_1078450" "unprognostic (9.33e-2)" "unprognostic (4.58e-2)" "unprognostic (2.81e-3)" "unprognostic (5.85e-3)" "unprognostic (2.25e-2)" "unprognostic (4.04e-3)" "unprognostic (1.09e-1)" "unprognostic (4.95e-2)" "unprognostic (5.83e-2)" "unprognostic (3.71e-1)" "unprognostic (2.16e-1)" "unprognostic (1.46e-1)" "unprognostic (2.09e-1)" "unprognostic (1.16e-1)" "unprognostic (3.70e-2)" "unprognostic (1.21e-1)" "unprognostic (2.18e-2)" 1.6 0.7 0.7 9.7 0.7 2.4 6.7 0.6 1.2 0.5 0.4 2.1 2.0 0.5 0.2 0.4 0.4 1.6 0.4 0.8 0.7 0.3 2.5 1.6 23.2 1.5 1.5 0.2 0.3 0.2 0.1 3.2 2.0 0.5 2.7 0.3 1.1 0.4 0.1 0.2 3.9 1.8 1.0 12.9 2.2 0.4 1.8 2.5 0.3 0.2 23.3 3.0 0.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.2 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 41.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.1 0.6 0.2 33.1 49.0 12.3 0.0 2.7 0.0 0.3 11.8 0.9 0.0 20.4 0.0 77.0 0.1 0.1 22.1 78.9 0.0 0.0 0.9 1.8 34.5 23.5 0.1 8.5 0.7 0.7 0.6 1.2 0.8 0.7 1.5 1.5 2.0 1.0 1.8 2.1 0.1 0.0 0.5 0.3 53.6 0.4 0.1 0.0 0.0 0.1 1.8 1.1 0.7 1.5 0.0 0.0 0.0 0.4 4.0 0.0 0.0 0.0 2.2 0.1 0.0 0.6 0.0 1.7 0.0 0.2 0.3 0.4 0.0 0.1 2.5 0.0 0.0 0.3 78.6 0.0 0.0 0.0 0.0 23.5 8.0 1.0 0.0 17.5 0.0 1.9 13.8 0.1 0.0 0.0 0.0 0.3 0.0 0.0 39.6 0.0 0.0 0.1 0.7 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.7 2.2 0.0 0.1 0.1 CD2BP2 "LIN1, PPP1R59, Snu40, U5-52K" ENSG00000169217 "CD2 cytoplasmic tail binding protein 2" O95400 16 30350773-30355308 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041508, HPA061309" Enhanced Enhanced "Nuclear speckles,Cytosol" Yes No "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 1: Pancreatic cells - Digestion" "Nuclear speckles" Cytosol "HPA041508: AB_2677523, HPA061309: AB_2684476" "unprognostic (5.66e-2)" "unprognostic (7.50e-3)" "unprognostic (1.47e-1)" "unprognostic (2.82e-2)" "unprognostic (1.65e-1)" "unprognostic (2.78e-1)" "prognostic unfavorable (1.84e-5)" "unprognostic (1.71e-2)" "unprognostic (1.16e-1)" "unprognostic (9.76e-2)" "unprognostic (2.30e-2)" "unprognostic (7.47e-2)" "unprognostic (2.09e-3)" "unprognostic (1.44e-1)" "unprognostic (3.22e-2)" "unprognostic (1.75e-1)" "unprognostic (1.66e-1)" 31.1 49.3 38.9 34.0 39.7 23.9 32.9 38.0 41.5 39.6 34.0 39.3 29.9 45.0 24.9 35.3 41.0 22.0 35.2 39.9 41.2 42.8 27.3 32.8 38.8 41.4 39.8 36.9 40.7 42.5 42.7 24.4 39.1 38.3 23.7 16.2 30.0 35.5 46.9 33.6 35.2 31.6 39.0 46.4 36.9 24.0 41.6 35.7 42.5 26.6 43.7 37.0 30.1 42.0 55.4 65.7 54.4 49.4 44.3 41.9 46.0 60.0 71.5 66.8 71.3 50.6 64.9 84.6 72.3 65.5 61.4 59.4 57.0 70.3 53.6 50.6 66.6 35.9 67.7 60.3 63.6 51.3 63.4 45.2 58.7 74.2 47.3 45.6 70.3 62.1 41.4 63.2 67.7 132.1 71.6 43.6 73.8 42.9 38.5 104.2 45.3 64.3 54.2 54.7 44.7 85.1 40.2 69.9 42.0 44.7 66.4 41.1 50.6 76.3 53.3 38.9 53.1 105.0 82.3 78.5 52.5 47.2 64.0 107.4 61.7 116.6 71.3 76.3 56.8 87.5 57.3 66.7 55.8 97.3 47.6 58.9 121.9 74.5 102.7 67.1 94.4 79.6 38.9 39.7 38.0 41.5 39.9 41.2 41.4 39.8 39.1 39.0 41.6 42.0 38.1 32.1 29.0 7.2 39.5 28.8 49.6 58.4 31.9 29.8 33.2 29.6 26.5 45.8 41.2 36.8 20.9 61.0 57.0 50.5 60.7 83.6 19.9 41.7 30.7 42.8 33.0 22.3 6.7 97.5 58.1 36.4 28.1 45.2 47.6 33.4 28.2 13.9 69.7 11.8 7.1 32.7 36.7 38.3 23.6 14.2 35.4 34.0 39.2 8.4 84.1 47.6 97.9 3.5 10.7 87.8 64.9 35.7 52.7 40.7 60.3 81.5 46.3 29.0 39.5 30.5 44.6 38.5 40.1 27.4 30.4 88.7 41.9 38.9 31.6 50.7 CDC20 "CDC20A, p55CDC" ENSG00000117399 "Cell division cycle 20" Q12834 1 43358981-43363203 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 53.9;lymphoid tissue: 52.6;testis: 49.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 65.0;Early spermatids: 135.0;Erythroid cells: 96.0;Extravillous trophoblasts: 146.2;Spermatocytes: 126.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7 "memory B-cell: 4.2;memory CD4 T-cell: 3.2;memory CD8 T-cell: 3.5;NK-cell: 9.5;T-reg: 11.6" "Group enriched" "Detected in many" 9 "B-cells: 4.2;NK-cells: 9.5;T-cells: 11.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB004525, HPA045842, HPA055288" Enhanced Enhanced Nucleoplasm,Cytosol Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "CAB004525: AB_628089, HPA045842: AB_2679470, HPA055288: AB_2682773" "unprognostic (1.66e-2)" "unprognostic (1.09e-1)" "unprognostic (1.73e-2)" "unprognostic (2.14e-3)" "unprognostic (1.58e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (4.00e-8)" "unprognostic (9.06e-3)" "unprognostic (1.17e-2)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.32e-4)" "unprognostic (8.55e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.84e-2)" "unprognostic (2.28e-1)" "unprognostic (2.01e-1)" "unprognostic (1.29e-2)" 1.6 1.5 0.6 16.2 1.1 53.9 5.2 0.8 1.3 3.5 0.4 14.8 13.7 2.3 2.5 27.2 1.7 1.2 0.9 0.7 1.1 2.3 1.7 2.5 32.6 1.3 1.1 0.7 0.6 0.2 0.3 9.7 1.1 0.8 16.0 0.2 4.4 0.7 0.3 11.3 12.2 7.3 0.8 11.7 7.0 49.1 1.7 52.6 1.7 0.2 50.8 3.3 7.0 1.3 311.9 148.2 202.8 133.4 6.9 17.6 193.5 140.3 125.0 400.0 211.4 234.5 250.9 178.3 80.1 130.1 140.6 212.8 225.3 267.9 331.5 140.8 165.6 261.4 143.6 147.3 2.1 184.3 91.4 6.0 12.4 278.2 249.6 35.1 172.2 167.5 120.2 119.3 184.0 120.4 179.2 113.5 257.2 147.0 196.9 255.8 277.9 112.9 98.5 81.3 119.2 58.9 248.1 165.8 76.6 154.9 116.3 231.7 90.2 118.9 276.2 133.7 445.0 90.6 86.7 185.7 85.2 227.6 181.6 0.0 0.1 0.0 0.3 0.0 0.0 4.2 3.2 3.5 0.9 0.9 0.1 0.3 0.7 9.5 0.0 0.2 11.6 2.8 0.6 1.1 0.8 1.3 0.7 1.1 1.3 1.1 1.1 0.8 1.7 1.3 2.1 0.0 1.1 0.0 12.2 10.5 3.8 17.6 6.2 0.5 6.4 9.7 0.7 1.5 4.8 0.0 0.0 65.0 2.8 16.9 0.0 2.2 135.0 14.6 2.4 4.5 0.0 96.0 0.2 0.4 146.2 9.3 11.7 4.6 0.0 46.5 7.9 1.3 37.4 0.0 0.0 18.5 24.4 6.2 7.5 18.5 2.8 9.3 0.0 0.0 1.8 0.3 0.0 0.0 1.6 0.7 0.5 1.9 34.4 2.7 3.2 3.1 8.3 2.9 0.0 1.0 25.4 126.5 39.8 47.3 8.4 10.7 5.1 1.6 37.5 7.4 CDC25B ENSG00000101224 "Cell division cycle 25B" P30305 20 3786772-3806121 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "B-cells: 7.2;NK-cells: 18.1;T-cells: 28.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038892, HPA038893, HPA075215" Enhanced Uncertain "Vesicles,Mitotic spindle" Yes Yes "Cluster 20: T-cells - T-cell receptor" "Cluster 64: Macrophages - Immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Mitotic spindle" "HPA038892: AB_2676258, HPA038893: AB_2676259, HPA075215: " "unprognostic (4.69e-2)" "unprognostic (5.74e-2)" "unprognostic (2.93e-2)" "prognostic unfavorable (4.76e-4)" "unprognostic (1.13e-1)" "unprognostic (4.23e-1)" "prognostic unfavorable (1.19e-4)" "unprognostic (1.31e-2)" "unprognostic (4.92e-2)" "unprognostic (2.74e-1)" "unprognostic (1.67e-1)" "unprognostic (6.03e-2)" "prognostic unfavorable (2.94e-13)" "unprognostic (1.15e-1)" "unprognostic (2.38e-1)" "unprognostic (3.94e-1)" "unprognostic (9.46e-2)" 29.2 15.6 30.5 28.8 32.4 29.4 25.1 39.2 33.2 41.7 23.2 37.6 14.4 35.0 9.4 27.1 31.5 17.9 16.3 27.6 32.5 31.3 24.8 78.4 47.6 31.3 29.9 37.4 12.8 3.8 45.7 31.1 30.2 25.4 11.3 7.8 16.7 8.9 10.5 21.8 41.2 14.2 27.4 56.1 30.1 12.4 30.9 44.7 41.8 6.3 32.8 35.8 30.2 35.8 129.6 273.2 36.5 60.0 43.8 43.0 19.3 63.3 95.3 103.1 75.9 49.2 182.9 91.3 27.5 65.4 253.5 183.5 50.6 105.8 50.2 36.2 54.4 49.4 88.5 59.6 178.4 38.6 25.0 41.1 85.0 95.4 115.7 35.6 58.4 44.2 33.3 232.7 63.1 105.5 119.0 57.7 27.3 90.9 116.9 62.0 102.6 67.5 73.2 12.2 25.8 56.9 148.6 140.8 78.1 31.7 48.1 20.4 48.6 55.1 66.2 101.5 85.0 57.8 97.8 36.8 28.1 38.0 54.6 3.9 2.4 0.0 22.7 3.4 21.3 5.8 22.6 23.3 2.4 7.2 18.6 21.6 0.3 18.1 1.7 1.3 28.2 11.2 30.5 32.4 39.2 33.2 27.6 32.5 31.3 29.9 30.2 27.4 30.9 35.8 14.0 9.6 21.7 18.6 21.7 11.2 6.0 10.9 7.4 14.4 4.8 5.5 8.6 8.6 4.5 7.3 2.1 11.9 30.6 5.8 0.0 9.9 0.7 2.7 20.6 27.1 7.8 32.6 39.2 4.8 17.7 15.7 17.3 5.4 1.3 11.5 14.3 13.7 30.4 3.3 38.0 10.4 12.2 14.8 9.4 1.1 7.2 12.4 17.8 6.5 8.8 8.3 44.3 22.6 13.2 15.0 4.3 9.1 49.6 6.0 5.5 11.1 3.7 2.6 0.0 26.5 14.0 2.3 12.3 10.3 11.2 3.6 36.4 7.1 10.9 4.4 CDC42 "CDC42Hs, G25K" ENSG00000070831 "Cell division cycle 42" P60953 1 22025511-22101360 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" Hydrolase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004360, HPA069590" Approved Supported "Microtubules,Cytokinetic bridge" Yes No 2700000 "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "Microtubules, Cytokinetic bridge" "CAB004360: AB_627233, HPA069590: AB_2732138" "unprognostic (9.40e-2)" "unprognostic (1.37e-1)" "unprognostic (9.45e-3)" "unprognostic (5.11e-2)" "unprognostic (1.73e-1)" "unprognostic (9.72e-2)" "prognostic unfavorable (5.28e-5)" "unprognostic (1.09e-1)" "unprognostic (7.92e-3)" "unprognostic (1.86e-2)" "unprognostic (3.90e-2)" "unprognostic (9.41e-2)" "unprognostic (9.72e-3)" "unprognostic (2.71e-1)" "unprognostic (3.88e-2)" "unprognostic (6.38e-2)" "unprognostic (2.09e-1)" 177.4 116.1 91.7 160.2 96.5 402.9 142.7 100.1 113.8 128.6 98.4 198.2 142.3 131.3 99.8 162.3 124.8 131.7 117.0 95.2 108.8 158.8 153.5 154.1 167.9 115.5 103.7 105.9 82.5 128.4 59.6 170.3 108.4 108.3 185.4 95.9 103.8 107.5 119.9 132.0 156.9 175.0 107.4 157.5 159.9 64.2 102.2 157.7 110.6 120.9 216.8 194.8 114.9 127.1 341.9 146.4 272.2 222.0 295.0 306.4 274.2 347.3 318.8 365.5 336.2 178.0 374.5 253.1 272.8 416.7 136.2 210.7 241.1 369.3 431.1 332.4 180.1 438.1 184.5 225.4 259.1 388.5 350.5 285.6 396.6 341.0 195.2 234.7 535.6 157.8 250.8 273.4 430.2 135.6 242.9 307.5 170.2 242.9 179.3 199.6 297.6 243.3 316.2 301.3 183.4 175.8 293.4 228.7 263.4 296.3 242.3 219.1 466.3 265.3 265.2 349.3 207.8 148.6 355.9 305.8 234.5 419.3 277.6 244.3 200.6 255.1 142.4 282.3 144.3 108.0 152.0 146.7 162.3 103.4 109.5 143.5 308.3 145.0 352.2 107.2 157.4 244.8 91.7 96.5 100.1 113.8 95.2 108.8 115.5 103.7 108.4 107.4 102.2 127.1 502.1 60.9 51.8 20.9 301.0 450.6 385.5 266.0 136.1 119.1 281.1 179.6 86.9 231.6 168.0 312.6 18.8 349.6 470.1 434.9 375.6 441.3 38.0 350.5 356.5 307.7 300.4 243.0 58.5 441.9 499.6 225.2 152.4 425.8 163.6 138.2 277.0 230.9 439.2 106.0 71.0 315.4 187.2 585.4 875.2 41.3 157.8 443.4 423.4 53.4 654.9 102.5 286.3 41.7 72.9 570.5 369.7 177.1 192.9 323.1 283.1 578.2 176.2 65.2 236.7 174.2 308.3 155.3 116.2 176.6 556.6 551.6 379.2 178.6 286.7 469.6 CDC6 CDC18L ENSG00000094804 "Cell division cycle 6" Q99741 17 40287879-40304657 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.2;lymphoid tissue: 17.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 23.2;Erythroid cells: 37.2;Extravillous trophoblasts: 34.6;Plasma cells: 31.6;Spermatocytes: 69.5;Spermatogonia: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.6" "Group enriched" "Detected in many" 6 "dendritic cells: 3.6;NK-cells: 1.5;T-cells: 2.4" "Cell line enhanced" "Detected in all" "SK-BR-3: 500.3" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA050114, HPA065070" Approved Approved "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "Cytokinetic bridge, Mitotic spindle" "HPA050114: AB_2681021, HPA065070: AB_2732729" "unprognostic (1.29e-1)" "unprognostic (7.22e-2)" "unprognostic (1.23e-3)" "unprognostic (7.97e-2)" "unprognostic (7.12e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (5.96e-8)" "unprognostic (2.31e-3)" "unprognostic (1.46e-3)" "unprognostic (1.41e-1)" "prognostic unfavorable (2.90e-4)" "unprognostic (5.47e-2)" "unprognostic (3.00e-15)" "unprognostic (1.86e-2)" "unprognostic (1.35e-1)" "unprognostic (3.95e-3)" "unprognostic (3.88e-2)" 2.1 1.9 0.5 13.7 0.8 27.2 3.4 0.2 1.9 3.2 0.0 8.4 7.5 2.2 1.1 5.7 1.0 2.8 0.6 1.1 0.1 0.5 3.0 1.4 16.4 0.1 0.0 0.9 1.9 0.8 0.5 9.3 0.3 1.1 8.7 0.5 1.3 1.2 0.3 2.8 6.7 3.7 0.0 3.7 3.6 10.1 0.2 16.7 1.7 0.5 17.1 4.3 1.8 0.6 155.1 119.0 115.1 86.5 6.7 12.7 118.0 159.9 49.0 149.2 166.5 135.8 64.9 123.9 99.6 35.9 85.9 214.0 112.2 76.2 148.9 64.5 98.4 96.2 122.3 134.6 4.4 133.3 55.1 4.7 8.1 156.4 107.1 14.8 46.9 84.2 183.0 109.0 71.9 95.8 199.3 43.3 101.6 96.9 48.7 145.0 286.8 119.9 30.3 184.8 85.6 76.9 146.9 500.3 55.4 100.3 100.8 120.0 34.7 95.5 146.3 170.8 196.1 46.1 103.6 222.8 84.6 93.9 109.2 0.1 0.1 0.0 0.8 0.0 0.5 0.4 0.6 1.1 0.7 0.3 0.4 1.1 0.1 1.5 0.0 3.6 2.4 0.6 0.5 0.8 0.2 1.9 1.1 0.1 0.1 0.0 0.3 0.0 0.2 0.6 2.2 0.0 2.0 0.7 4.9 4.2 1.1 3.7 3.4 0.2 2.1 2.2 0.9 1.5 1.3 0.0 0.0 23.2 2.3 7.8 0.0 1.3 2.2 1.3 2.9 2.1 0.0 37.2 2.0 0.6 34.6 5.6 3.6 5.1 0.0 8.1 1.1 0.9 8.3 0.0 0.7 6.1 0.0 1.3 2.1 1.0 2.8 1.5 0.0 0.0 0.0 0.4 2.1 0.0 0.2 1.5 3.0 0.7 31.6 1.3 0.8 0.2 0.2 0.3 13.1 0.6 4.6 69.5 57.2 9.1 1.6 16.7 3.3 1.9 9.3 2.4 CDC7 "CDC7L1, HsCdc7, Hsk1, huCdc7" ENSG00000097046 "Cell division cycle 7" O00311 1 91500851-91525764 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 16.9" "Cell type enhanced" "Detected in many" "Early spermatids: 37.8;Erythroid cells: 23.1;Spermatocytes: 30.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002669, HPA035831" Enhanced Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" Yes No "Cluster 20: T-cells - T-cell receptor" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 30: Mammary glandular cells - Lactation" Nucleoplasm "Cytokinetic bridge, Mitotic spindle" "CAB002669: , HPA035831: AB_2674807" "unprognostic (6.84e-2)" "unprognostic (6.01e-2)" "unprognostic (4.64e-2)" "unprognostic (7.02e-3)" "unprognostic (5.57e-2)" "unprognostic (3.57e-3)" "prognostic unfavorable (3.15e-6)" "unprognostic (6.52e-2)" "unprognostic (2.23e-2)" "unprognostic (1.36e-3)" "unprognostic (2.04e-2)" "unprognostic (1.75e-2)" "prognostic unfavorable (1.89e-15)" "unprognostic (9.44e-3)" "unprognostic (2.49e-2)" "unprognostic (1.09e-1)" "unprognostic (5.39e-2)" 1.9 2.7 3.6 6.0 3.8 13.8 2.1 6.3 4.8 2.1 1.6 3.0 3.1 1.8 1.7 3.5 1.3 1.7 1.4 3.8 3.4 4.3 1.5 4.2 9.3 2.9 3.7 2.5 1.6 0.8 4.0 5.9 3.1 1.9 4.6 14.1 1.7 1.4 0.5 5.1 3.7 2.4 2.8 12.1 1.8 16.9 3.2 10.9 1.7 0.5 9.4 2.4 2.3 3.5 32.0 9.4 59.1 17.3 1.4 7.6 18.8 12.0 9.1 22.6 24.3 19.6 10.8 22.5 16.1 7.7 19.8 13.7 39.8 13.5 29.4 36.8 34.3 33.7 27.9 9.5 2.1 37.0 11.9 4.2 4.0 21.0 11.9 4.1 8.9 30.9 44.8 31.4 15.2 11.8 31.5 33.5 48.9 17.2 21.6 38.9 49.5 14.5 10.2 24.0 44.7 18.6 37.5 10.2 21.6 14.3 9.8 18.2 7.3 25.8 22.7 20.6 17.9 11.6 15.6 57.9 9.4 36.0 9.4 0.0 1.0 0.0 3.8 0.7 3.2 0.9 2.8 3.5 2.3 0.9 1.5 3.0 0.1 1.6 0.2 1.4 4.6 1.4 3.6 3.8 6.3 4.8 3.8 3.4 2.9 3.7 3.1 2.8 3.2 3.5 1.9 0.0 1.1 3.3 3.2 5.9 1.2 2.7 3.4 8.2 14.4 1.4 2.1 0.0 1.3 1.8 0.0 8.2 4.1 0.6 3.9 1.5 37.8 1.1 4.9 4.1 0.0 23.1 18.3 2.6 6.3 3.1 2.6 1.9 4.5 15.4 4.2 0.2 2.7 3.3 19.6 1.8 6.1 2.2 2.9 18.7 0.9 1.6 3.6 5.6 2.1 1.6 6.2 16.6 3.1 1.2 1.7 0.7 7.1 0.9 0.5 0.4 2.0 5.1 6.6 1.5 4.1 30.5 21.4 4.3 3.7 2.2 5.3 7.6 3.6 1.0 CDCA2 "PPP1R81, Repo-Man" ENSG00000184661 "Cell division cycle associated 2" Q69YH5 8 25459199-25507911 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 6.5;lymphoid tissue: 11.4;testis: 19.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 23.3;Early spermatids: 49.9;Erythroid cells: 19.0;Late spermatids: 24.2;Spermatocytes: 66.6;Spermatogonia: 27.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA026293, HPA030049" Enhanced Supported Nucleoplasm Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA026293: AB_1846384, HPA030049: AB_10600862" "unprognostic (2.12e-1)" "unprognostic (4.75e-3)" "prognostic favorable (9.62e-4)" "unprognostic (2.92e-2)" "unprognostic (9.69e-2)" "unprognostic (3.56e-2)" "unprognostic (2.50e-5)" "unprognostic (1.47e-3)" "unprognostic (6.06e-2)" "unprognostic (2.91e-3)" "unprognostic (1.32e-3)" "unprognostic (1.99e-1)" "prognostic unfavorable (2.30e-14)" "unprognostic (1.36e-2)" "unprognostic (4.02e-1)" "unprognostic (1.91e-1)" "unprognostic (5.30e-2)" 0.2 0.0 0.0 2.6 0.0 6.5 0.6 0.1 0.0 0.2 0.1 1.9 1.6 0.3 0.0 1.4 0.1 0.3 0.3 0.0 0.1 0.0 0.1 0.2 5.3 0.2 0.2 0.0 0.0 0.0 0.0 1.2 0.2 0.1 2.2 0.1 0.2 0.0 0.0 1.1 1.8 0.8 0.0 0.8 0.9 19.4 0.3 11.4 0.1 0.1 6.7 0.6 0.3 0.1 36.5 30.2 29.4 24.2 2.3 4.5 20.2 37.7 22.6 32.9 32.4 25.7 15.8 42.6 16.0 16.2 34.6 31.6 42.9 20.0 48.5 16.2 12.0 43.2 22.4 15.2 0.6 18.4 19.4 2.5 1.0 23.5 15.8 3.3 24.5 24.5 33.6 45.8 30.6 13.9 54.5 8.7 31.0 24.1 14.5 26.3 33.4 15.2 9.2 18.7 12.0 13.3 33.3 16.1 14.3 14.7 17.4 9.4 16.6 23.9 39.3 44.7 35.6 7.1 16.5 44.4 17.7 24.3 40.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.2 0.0 0.3 0.1 0.2 0.0 1.1 0.0 2.7 1.1 0.5 1.7 0.0 0.7 0.9 0.8 23.3 0.0 0.2 0.0 0.0 7.2 0.5 1.8 0.0 0.2 49.9 0.8 1.2 1.1 0.0 19.0 0.2 0.0 13.4 2.5 4.1 1.4 0.0 8.8 1.1 0.1 4.1 0.0 0.1 1.3 0.0 2.9 0.6 24.2 1.2 2.1 0.0 0.0 0.6 0.1 2.1 0.5 0.6 0.2 0.1 0.0 15.8 0.5 0.5 1.2 0.9 0.5 13.1 0.1 2.1 66.6 27.8 10.7 0.9 1.6 2.9 1.3 3.6 0.5 CDCA5 ENSG00000146670 "Cell division cycle associated 5" Q96FF9 11 65066300-65084164 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 53.4;lymphoid tissue: 27.6;testis: 37.8" "Cell type enhanced" "Detected in many" "Early spermatids: 56.5;Extravillous trophoblasts: 38.3;Late spermatids: 116.9;Spermatocytes: 50.4;Spermatogonia: 31.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "NK-cell: 2.8;T-reg: 2.0" "Group enriched" "Detected in many" 5 "NK-cells: 2.8;T-cells: 2.0" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in single" "white matter: 1.4" "Low region specificity" "Detected in many" "HPA023691, HPA076007" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA023691: AB_1846392, HPA076007: " "unprognostic (3.14e-2)" "unprognostic (4.20e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.67e-4)" "unprognostic (2.15e-1)" "unprognostic (2.68e-1)" "prognostic unfavorable (8.21e-6)" "unprognostic (1.41e-3)" "unprognostic (7.55e-3)" "unprognostic (6.93e-2)" "prognostic unfavorable (8.72e-6)" "unprognostic (2.16e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.55e-3)" "unprognostic (1.86e-1)" "unprognostic (1.35e-1)" "unprognostic (8.97e-2)" 1.4 1.2 1.3 10.5 1.3 53.4 2.0 0.8 1.8 1.9 0.9 6.8 5.8 1.3 0.3 9.3 0.9 0.9 0.9 1.5 0.9 0.9 1.3 1.9 17.0 1.6 1.3 0.6 0.7 0.4 0.5 6.5 1.6 0.8 7.7 0.5 1.4 0.5 0.6 4.2 5.8 3.1 0.8 6.6 3.1 37.8 1.8 27.6 0.6 0.4 16.2 2.2 2.8 1.3 131.7 74.9 67.2 57.3 4.5 7.3 57.8 92.7 37.4 103.6 81.5 77.7 75.4 121.3 52.3 29.4 120.8 87.9 110.3 49.5 98.6 122.0 52.2 107.7 54.4 64.1 0.4 116.8 81.8 2.5 4.5 96.3 44.0 10.8 32.6 138.4 126.6 206.6 63.5 109.2 164.7 116.9 107.8 63.0 92.4 140.4 76.8 111.9 21.2 49.6 89.1 68.4 59.3 80.7 62.8 41.6 104.7 54.7 19.9 92.7 97.2 99.5 101.7 106.9 187.8 195.4 37.2 69.5 97.4 0.0 0.1 0.2 0.4 0.0 0.0 0.3 0.5 0.3 0.4 0.5 0.0 0.3 0.0 2.8 0.3 0.3 2.0 0.7 1.3 1.3 0.8 1.8 1.5 0.9 1.6 1.3 1.6 0.8 1.8 1.3 0.9 0.0 0.5 0.0 4.6 3.8 1.2 1.3 0.6 0.6 2.3 4.4 1.0 0.0 0.8 0.0 2.1 19.7 2.2 4.6 1.9 0.8 56.5 1.1 1.5 2.3 0.0 21.8 1.1 0.8 38.3 3.5 3.1 1.5 3.8 14.5 1.1 0.0 11.7 1.7 0.6 4.7 2.0 2.8 1.5 116.9 2.8 1.7 0.0 1.0 2.1 0.9 2.1 0.0 0.6 0.6 0.1 1.5 16.2 1.1 1.1 0.6 0.4 0.2 0.0 0.5 2.7 50.4 31.1 7.1 1.0 3.7 4.2 1.9 9.4 1.6 CDCA8 "BOR, DasraB, FLJ12042, MESRGP" ENSG00000134690 "Cell division cycle associated 8" Q53HL2 1 37692481-37709719 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.5;lymphoid tissue: 38.8;testis: 22.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 34.1;Extravillous trophoblasts: 26.0;Spermatocytes: 76.8;Spermatogonia: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA028120, HPA028258, HPA028783, CAB040294" Enhanced Supported "Nucleoplasm,Nucleoli,Cytokinetic bridge" Yes Yes "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoli "Nucleoplasm, Cytokinetic bridge" "CAB040294: , HPA028120: AB_10670556, HPA028258: AB_10669864, HPA028783: AB_10671092" "unprognostic (8.36e-2)" "unprognostic (2.00e-1)" "unprognostic (8.39e-2)" "unprognostic (7.75e-3)" "unprognostic (2.34e-1)" "unprognostic (5.42e-2)" "prognostic unfavorable (4.93e-10)" "unprognostic (4.30e-3)" "prognostic unfavorable (6.04e-4)" "unprognostic (3.00e-1)" "prognostic unfavorable (8.32e-4)" "unprognostic (3.78e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (6.39e-3)" "unprognostic (2.99e-1)" "unprognostic (3.18e-1)" "unprognostic (1.67e-1)" 1.0 1.1 0.7 7.9 1.0 33.5 2.0 0.2 0.9 1.7 0.0 9.4 8.3 1.3 1.8 9.2 1.0 1.1 0.6 0.5 0.4 0.8 1.3 1.5 19.5 0.6 0.4 0.6 0.8 0.5 0.6 4.4 0.5 0.7 11.3 1.9 1.8 0.5 0.3 6.3 7.3 2.8 0.3 4.9 4.9 22.5 0.6 38.8 0.6 0.5 22.7 2.0 2.9 0.7 108.5 45.5 84.4 62.1 3.6 7.0 57.2 79.6 39.5 137.2 96.6 71.9 78.8 130.2 31.5 50.5 54.5 59.4 97.8 52.4 141.9 86.8 44.9 116.8 49.2 57.3 0.8 113.8 58.4 2.8 3.8 77.1 67.3 15.3 60.9 91.1 100.7 135.6 99.1 47.7 106.1 68.9 98.8 61.7 62.8 102.2 115.6 74.4 31.0 43.8 75.4 33.3 87.5 40.6 52.4 71.7 60.1 42.4 37.3 67.8 70.6 39.2 126.0 91.4 128.1 176.3 31.6 104.7 79.6 0.0 0.7 1.3 1.5 1.6 2.8 1.7 3.6 2.2 0.7 1.4 1.1 2.3 3.0 4.1 3.9 1.2 5.9 1.7 0.7 1.0 0.2 0.9 0.5 0.4 0.6 0.4 0.5 0.3 0.6 0.7 0.8 0.0 0.5 1.3 4.8 3.3 0.8 2.4 1.8 1.3 1.9 1.5 0.7 2.8 0.4 0.0 0.0 17.1 1.9 12.4 0.0 1.2 1.0 1.7 1.6 1.9 3.6 34.1 1.2 0.6 26.0 2.9 6.6 2.5 0.0 12.0 3.6 1.0 11.6 1.7 0.9 8.2 2.0 3.5 1.9 2.8 1.5 3.7 1.8 0.0 1.6 0.1 2.1 0.5 0.9 2.4 4.0 1.2 15.8 1.3 1.9 0.6 4.7 1.0 19.7 0.2 6.3 76.8 42.0 17.1 2.7 2.9 5.5 1.2 13.2 1.2 CDK10 PISSLRE ENSG00000185324 "Cyclin dependent kinase 10" Q15131 16 89680737-89696354 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007451, HPA059634, HPA067060" Uncertain Supported "Nucleoplasm,Midbody,Midbody ring" Yes Yes "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Midbody, Midbody ring" "HPA007451: AB_2732400, HPA059634: AB_2684090, HPA067060: AB_2685772" "unprognostic (7.89e-2)" "unprognostic (8.08e-2)" "unprognostic (3.74e-3)" "unprognostic (9.87e-2)" "unprognostic (1.76e-1)" "unprognostic (3.44e-2)" "unprognostic (4.53e-1)" "unprognostic (9.06e-2)" "unprognostic (2.99e-1)" "unprognostic (2.13e-1)" "prognostic favorable (2.69e-4)" "unprognostic (2.58e-2)" "unprognostic (2.93e-1)" "unprognostic (3.32e-2)" "unprognostic (1.79e-1)" "unprognostic (6.88e-2)" "prognostic favorable (3.63e-4)" 30.1 38.5 20.2 10.4 20.4 19.5 26.7 20.3 32.8 49.3 22.0 38.2 22.7 25.9 8.7 35.3 36.3 8.6 27.3 21.0 19.5 52.9 77.0 31.0 14.7 18.6 18.7 43.2 49.2 13.5 55.5 12.5 19.6 39.1 11.3 7.6 24.8 7.5 33.8 32.1 36.1 8.2 17.0 37.5 38.5 17.0 18.4 10.8 54.5 4.1 7.0 32.3 36.5 19.1 27.5 17.8 13.9 5.8 5.7 11.0 14.2 22.3 12.6 15.2 4.9 13.1 21.2 23.9 9.8 19.3 9.1 15.5 5.8 30.8 9.3 5.3 14.1 9.7 21.0 1.7 23.4 15.8 17.1 13.3 10.7 9.3 15.3 10.3 27.0 16.1 25.5 3.2 17.7 36.6 19.5 45.0 28.5 29.7 13.1 26.5 19.0 34.1 27.9 21.2 10.1 29.6 28.0 13.0 6.8 15.2 30.3 25.0 24.1 9.1 26.6 10.1 15.4 11.7 6.4 7.5 16.4 25.0 15.5 5.1 14.0 4.2 14.8 19.7 12.8 7.8 13.2 10.7 18.1 9.0 15.1 12.6 1.5 20.4 15.4 12.4 11.6 11.4 20.2 20.4 20.3 32.8 21.0 19.5 18.6 18.7 19.6 17.0 18.4 19.1 28.2 12.8 26.6 35.3 21.2 15.4 24.2 26.9 23.3 17.2 24.5 25.1 6.5 38.6 20.0 27.6 25.0 28.6 26.7 44.8 43.0 28.6 6.1 20.7 21.9 23.0 67.7 15.4 44.5 12.5 19.8 19.6 85.1 16.9 9.5 40.3 21.8 41.1 18.8 18.5 33.3 49.4 26.4 17.4 16.0 8.8 23.9 17.0 19.6 17.8 15.5 8.5 26.8 24.6 20.0 13.6 41.5 12.4 20.8 30.7 58.3 53.7 28.1 32.3 6.6 11.4 16.3 27.3 28.7 22.4 15.5 27.9 22.0 54.8 58.2 22.9 CDK17 "PCTAIRE2, PCTK2" ENSG00000059758 "Cyclin dependent kinase 17" Q00537 12 96278261-96400480 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 101.5;Oligodendrocytes: 259.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 134.8;TIME: 160.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015325 Approved Approved Nucleoplasm,Cytosol Yes No "Cluster 38: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Cytosol" "HPA015325: AB_1855090" "unprognostic (4.35e-1)" "unprognostic (2.79e-1)" "unprognostic (2.70e-1)" "unprognostic (3.56e-1)" "unprognostic (1.50e-1)" "unprognostic (4.96e-3)" "unprognostic (5.22e-3)" "unprognostic (1.23e-1)" "unprognostic (3.23e-2)" "unprognostic (2.75e-2)" "unprognostic (2.44e-1)" "unprognostic (5.96e-2)" "prognostic unfavorable (1.09e-6)" "unprognostic (4.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.92e-2)" "unprognostic (1.70e-2)" 21.4 11.2 26.3 18.9 45.9 48.1 18.4 23.0 34.7 13.2 8.3 17.0 11.9 26.2 9.1 14.6 13.9 16.2 11.4 36.7 28.6 11.6 16.3 20.6 21.7 23.2 23.0 15.7 10.5 10.6 8.0 31.8 23.0 14.0 12.2 19.3 8.7 11.1 8.8 11.0 11.5 29.5 27.4 21.8 10.5 26.6 28.5 24.8 11.6 12.3 22.2 17.1 12.8 54.0 15.4 12.5 32.5 8.9 15.9 41.2 24.1 34.8 46.9 29.1 27.2 7.7 8.8 22.7 23.0 24.5 15.6 13.8 19.8 20.9 39.5 24.9 15.5 32.7 8.5 10.9 34.4 17.9 18.4 30.0 21.3 43.0 77.1 51.8 134.8 18.9 24.7 18.1 66.8 9.5 17.0 28.1 14.4 7.6 22.8 29.2 18.0 19.8 35.1 12.7 17.1 11.7 19.9 18.4 25.9 24.7 14.0 15.7 160.5 25.6 10.0 13.8 18.7 26.0 21.1 24.1 9.6 7.6 19.2 66.7 6.4 17.1 22.2 9.3 24.0 17.5 17.9 25.1 10.0 16.6 25.0 21.7 23.2 31.4 9.0 7.3 15.8 16.6 26.3 45.9 23.0 34.7 36.7 28.6 23.2 23.0 23.0 27.4 28.5 54.0 58.1 16.0 6.5 54.5 37.3 26.8 10.7 8.6 19.4 11.8 13.8 9.8 11.9 7.2 10.3 9.2 16.7 12.0 64.4 7.2 0.0 4.9 3.3 17.6 10.0 51.7 15.0 17.9 101.5 3.6 27.9 24.0 21.4 17.2 18.3 8.9 34.2 10.8 12.1 5.0 59.2 7.9 4.1 14.5 20.7 4.1 9.9 16.7 17.8 64.6 8.6 22.6 32.0 52.3 259.2 7.4 3.4 9.4 64.7 12.5 6.5 8.6 15.4 9.6 6.6 22.7 22.0 8.8 21.6 24.2 25.9 13.7 63.2 10.7 6.0 15.1 CEACAM18 ENSG00000213822 "CEA cell adhesion molecule 18" A8MTB9 19 51478622-51490952 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 26 "intestine: 10.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "pancreatic cancer: 0.8;stomach cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "CACO-2: 4.3;OE19: 3.5;RT4: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA059487 Uncertain Approved Midbody Yes NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Midbody "HPA059487: AB_2684036" "unprognostic (1.12e-1)" "unprognostic (1.87e-2)" "unprognostic (1.00e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.5 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CEBPB "C/EBP-beta, CRP2, IL6DBP, LAP, NFIL6, TCF5" ENSG00000172216 "CCAAT enhancer binding protein beta" P17676 20 50190830-50192668 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 765.6;Suprabasal keratinocytes: 800.1;Syncytiotrophoblasts: 1409.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.7" "Group enriched" "Detected in many" 8 "granulocytes: 16.7;monocytes: 7.7" "Cell line enhanced" "Detected in all" "SK-MEL-30: 169.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB004213, HPA061355, HPA062267" Supported Enhanced Nucleoplasm Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB004213: AB_626772, HPA061355: AB_2684487, HPA062267: AB_2684731" "unprognostic (2.30e-2)" "unprognostic (2.64e-1)" "unprognostic (1.24e-2)" "unprognostic (1.09e-2)" "unprognostic (9.48e-2)" "unprognostic (2.24e-2)" "unprognostic (1.32e-1)" "unprognostic (1.40e-3)" "unprognostic (1.79e-2)" "unprognostic (9.85e-3)" "unprognostic (9.26e-3)" "unprognostic (6.55e-2)" "prognostic unfavorable (2.44e-12)" "unprognostic (7.29e-2)" "unprognostic (1.43e-1)" "unprognostic (2.45e-2)" "unprognostic (7.63e-2)" 160.7 125.5 26.6 63.9 29.4 43.2 86.5 24.4 29.8 95.5 36.7 60.0 13.1 72.4 5.8 43.2 94.9 27.6 59.3 29.7 32.4 39.3 228.7 139.5 11.2 34.8 36.4 89.6 35.6 10.8 28.4 37.8 29.2 60.3 7.1 4.6 49.1 12.3 202.2 99.1 43.4 15.5 35.7 93.1 57.7 9.0 33.3 6.3 57.5 44.3 7.3 64.9 67.2 31.5 26.4 11.8 1.3 13.9 63.7 24.9 112.7 34.9 54.6 23.5 20.7 12.0 23.9 17.1 64.5 14.5 115.4 35.3 3.7 34.2 15.9 12.5 8.3 5.2 15.0 17.8 78.3 8.7 32.9 26.7 88.5 29.9 52.9 49.0 3.3 17.4 25.4 31.0 15.0 9.9 4.1 19.0 7.3 24.8 33.6 12.3 3.4 20.1 7.9 6.3 6.7 4.4 28.9 70.7 169.6 7.4 18.8 48.1 4.5 48.6 37.2 42.1 34.0 64.6 29.5 15.9 88.7 19.6 21.6 8.6 3.5 12.5 0.5 6.8 0.1 0.6 0.4 0.6 1.5 0.3 0.4 0.2 16.7 0.5 7.7 0.0 0.3 0.8 26.6 29.4 24.4 29.8 29.7 32.4 34.8 36.4 29.2 35.7 33.3 31.5 83.3 35.3 67.6 16.3 64.2 724.2 371.8 48.3 241.9 3.9 244.6 244.5 48.7 130.1 35.6 46.0 0.0 185.0 208.1 83.4 31.3 32.9 9.9 305.3 417.4 74.9 66.7 33.9 18.4 13.2 681.2 605.1 102.4 410.5 51.4 10.8 94.9 402.7 345.7 3.3 8.6 102.5 24.4 500.4 438.5 10.6 129.5 765.6 217.1 37.5 159.0 87.6 61.8 0.5 1.8 19.2 60.9 96.3 102.7 346.5 61.9 74.2 29.8 5.6 157.8 466.2 356.7 1.1 13.3 162.1 800.1 1409.9 159.3 68.2 63.4 359.6 CELF2 "BRUNOL3, CUGBP2, Etr-3, NAPOR-2" ENSG00000048740 "CUGBP Elav-like family member 2" O95319 10 10798397-11336675 "Predicted intracellular proteins" "mRNA processing" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 78.9" "Cell type enhanced" "Detected in many" "Astrocytes: 558.0;Excitatory neurons: 1676.4;Inhibitory neurons: 576.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 200.2;HMC-1: 186.2;REH: 86.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016395, HPA035813" Enhanced Supported "Nucleoplasm,Vesicles,Midbody ring" Yes No "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Vesicles, Midbody ring" "CAB016395: AB_2086271, HPA035813: AB_2674797" "unprognostic (1.62e-2)" "unprognostic (1.52e-2)" "unprognostic (1.90e-2)" "unprognostic (3.55e-2)" "unprognostic (9.00e-2)" "prognostic favorable (7.61e-4)" "unprognostic (1.57e-1)" "unprognostic (3.77e-2)" "unprognostic (4.20e-2)" "unprognostic (5.22e-2)" "unprognostic (2.60e-3)" "unprognostic (2.83e-2)" "unprognostic (2.14e-1)" "unprognostic (1.44e-1)" "unprognostic (1.84e-1)" "unprognostic (2.31e-2)" "unprognostic (1.45e-1)" 39.6 5.7 33.7 30.7 42.7 78.9 17.7 0.2 42.0 14.2 0.0 16.5 9.2 15.0 5.0 21.4 13.3 17.2 37.5 42.5 7.2 3.0 4.3 28.2 42.4 0.9 13.9 46.8 4.4 3.5 6.5 8.6 0.4 14.1 17.9 35.4 9.6 12.2 17.6 8.6 23.4 23.2 8.6 31.1 10.3 7.6 23.7 60.7 8.5 15.0 29.4 16.2 8.0 21.0 0.1 0.0 47.6 0.0 7.4 2.7 5.3 7.0 0.2 1.1 0.2 0.1 0.0 0.1 5.3 6.1 0.0 0.1 6.8 0.2 0.4 40.4 11.9 200.2 0.7 0.0 1.7 58.0 186.2 3.0 0.3 0.4 0.0 0.7 6.7 70.6 9.3 80.7 59.6 0.0 71.9 42.0 19.3 0.0 0.0 86.7 50.8 18.0 3.4 0.0 7.1 0.5 0.1 0.2 51.1 15.2 0.0 39.0 0.1 8.9 2.5 29.9 0.1 30.7 30.1 9.3 2.9 68.8 21.6 68.0 43.2 90.8 54.8 57.5 69.2 48.1 54.1 60.5 53.4 51.0 56.1 52.7 115.1 73.5 67.8 37.9 60.9 63.5 33.7 42.7 0.2 42.0 42.5 7.2 0.9 13.9 0.4 8.6 23.7 21.0 20.4 160.3 147.3 558.0 165.6 19.9 3.4 5.8 12.5 68.2 18.8 13.7 122.7 5.7 22.4 12.9 102.2 1.1 233.5 11.8 15.6 1.6 135.9 5.3 11.3 34.7 59.3 45.2 1676.4 2.1 0.9 106.0 11.2 17.0 128.5 0.7 13.2 5.1 90.0 134.6 576.9 37.5 24.4 261.4 134.3 110.3 111.6 192.9 115.6 376.6 263.6 90.5 256.4 324.7 21.6 1.5 16.9 89.5 124.3 10.1 2.4 1.0 5.8 99.2 52.6 117.6 33.7 4.1 11.5 5.7 14.5 1.9 232.5 8.5 23.8 2.4 CENPC "CENP-C, CENPC1, hcp-4, MIF2" ENSG00000145241 "Centromere protein C" Q03188 4 67468762-67545503 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049740, HPA058252" Supported "Nucleoplasm,Nuclear bodies,Kinetochore,Midbody" Yes Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 21: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear bodies, Kinetochore" "Nucleoplasm, Midbody" "HPA049740: , HPA058252: AB_2683654" "unprognostic (4.35e-1)" "unprognostic (6.41e-3)" "unprognostic (4.31e-3)" "unprognostic (7.85e-2)" "unprognostic (6.31e-2)" "unprognostic (3.85e-3)" "unprognostic (6.40e-2)" "prognostic favorable (9.67e-4)" "unprognostic (3.22e-2)" "unprognostic (7.13e-2)" "unprognostic (8.35e-2)" "unprognostic (4.32e-2)" "prognostic favorable (5.63e-4)" "unprognostic (2.40e-1)" "unprognostic (1.92e-1)" "unprognostic (1.15e-1)" "unprognostic (1.92e-3)" 1.5 1.6 2.5 1.0 3.2 3.6 3.3 5.6 2.6 2.8 0.2 2.0 1.1 3.1 2.3 1.5 2.9 1.1 1.5 2.2 2.0 2.0 1.4 1.5 1.8 1.3 1.8 5.6 3.8 1.5 2.5 1.3 1.7 2.9 1.2 2.7 2.0 1.6 1.1 2.3 1.8 1.5 1.3 2.0 2.1 1.7 1.7 2.0 3.1 1.1 1.5 2.0 2.3 2.8 0.4 0.5 1.6 0.9 1.9 1.1 0.9 0.6 0.5 0.7 0.5 0.7 1.3 2.7 0.8 0.8 0.2 0.8 2.2 0.9 1.2 0.8 0.4 2.1 0.9 0.9 0.6 3.9 0.8 1.4 0.3 0.5 1.3 1.2 0.4 1.8 3.0 1.6 1.1 0.7 5.3 3.5 1.8 0.8 0.3 2.4 4.0 0.9 1.0 0.8 2.8 1.3 1.2 2.5 0.7 1.6 0.7 1.3 0.4 1.0 0.5 0.7 0.5 1.3 0.5 2.7 1.1 2.2 0.6 0.5 0.2 0.5 0.7 0.4 0.3 0.8 0.8 0.9 0.2 1.1 1.2 0.9 0.2 0.5 0.2 0.4 0.4 0.2 2.5 3.2 5.6 2.6 2.2 2.0 1.3 1.8 1.7 1.3 1.7 2.8 53.1 32.1 35.5 38.8 68.4 15.2 25.3 17.7 35.9 53.7 26.0 32.3 24.3 18.6 31.6 16.5 14.6 20.2 75.0 17.7 11.7 13.5 4.1 21.0 39.0 33.7 13.1 31.7 58.5 16.7 12.9 41.3 35.7 25.1 26.6 39.8 23.2 14.1 12.8 52.2 57.0 18.4 18.3 16.7 7.9 5.5 34.8 26.7 16.0 31.9 27.4 31.6 60.8 46.3 74.6 14.6 13.0 25.6 89.1 15.3 24.2 20.4 27.2 29.0 19.7 54.1 34.2 47.2 44.4 34.7 9.2 18.3 69.8 43.3 16.4 23.9 CENPE "KIF10, PPP1R61" ENSG00000138778 "Centromere protein E" Q02224 4 103105349-103198445 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Developmental protein, Motor protein" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 10.0;lymphoid tissue: 9.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 75.1;Extravillous trophoblasts: 28.4;Granulosa cells: 32.0;Spermatocytes: 75.3;Spermatogonia: 51.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA011110, HPA042294" Enhanced Enhanced "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA011110: , HPA042294: AB_10797386" "unprognostic (1.62e-1)" "unprognostic (1.03e-1)" "unprognostic (5.64e-3)" "unprognostic (2.55e-2)" "unprognostic (1.65e-1)" "unprognostic (3.44e-2)" "unprognostic (2.40e-8)" "unprognostic (2.49e-3)" "unprognostic (1.59e-2)" "unprognostic (3.38e-1)" "unprognostic (4.88e-5)" "unprognostic (1.15e-2)" "unprognostic (0.00e+0)" "unprognostic (9.95e-3)" "unprognostic (2.49e-1)" "unprognostic (1.05e-1)" "unprognostic (2.37e-1)" 0.4 0.2 0.4 2.7 0.4 10.0 0.6 0.3 0.5 0.4 0.4 1.8 1.5 0.6 0.0 2.0 0.2 0.8 0.2 0.3 0.6 0.2 0.5 0.8 5.6 0.5 0.5 0.1 0.1 0.3 0.0 1.4 0.9 0.3 2.0 0.4 0.3 0.2 0.0 2.0 1.7 1.1 0.3 1.2 1.1 4.1 0.5 9.2 0.2 0.6 4.9 0.8 0.6 0.5 42.6 11.8 42.2 20.5 2.7 6.2 8.4 36.7 18.2 26.9 17.9 19.6 22.2 28.6 9.2 13.7 19.2 18.2 30.3 15.1 42.2 35.9 11.3 33.5 26.8 13.6 0.4 39.9 18.6 1.8 1.1 21.7 18.0 6.0 22.9 25.2 34.4 32.5 34.8 15.6 31.5 18.9 13.8 17.0 17.9 20.9 38.5 9.3 8.0 8.4 19.3 11.5 32.9 22.9 9.0 16.0 12.9 13.9 26.1 25.8 27.2 27.2 38.6 15.9 28.6 28.8 14.2 21.7 27.8 2.9 0.0 0.3 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.3 1.5 0.2 0.6 0.0 0.4 0.4 0.3 0.5 0.3 0.6 0.5 0.5 0.9 0.3 0.5 0.5 1.4 3.2 2.2 1.0 6.6 3.6 1.5 2.9 0.0 7.6 1.8 2.7 1.9 0.0 1.3 0.0 8.4 12.7 3.9 4.7 0.0 0.5 7.7 3.5 5.7 4.2 1.2 75.1 2.0 0.0 28.4 6.5 4.6 6.9 7.0 32.0 4.2 0.9 14.1 0.0 1.9 4.3 4.1 10.4 5.7 3.5 0.9 9.6 0.0 0.0 6.0 1.3 2.1 0.5 3.1 1.8 1.4 2.6 16.0 1.4 0.8 0.3 0.3 2.6 0.0 5.7 7.4 75.3 51.0 8.3 2.8 3.6 6.6 7.0 11.6 1.9 CENPF hcp-1 ENSG00000117724 "Centromere protein F" P49454 1 214603195-214664571 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, DNA synthesis, Mitosis, Myogenesis" "Developmental protein" "Cancer-related genes, Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.8;lymphoid tissue: 33.0" "Cell type enhanced" "Detected in many" "Early spermatids: 84.4;Erythroid cells: 268.7;Extravillous trophoblasts: 78.8;Granulosa cells: 165.8;Spermatocytes: 107.5;Spermatogonia: 107.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "HPA052382, HPA064308, CAB070134" Enhanced Supported Nucleoplasm Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB070134: AB_2229328, HPA052382: AB_2681808, HPA064308: AB_2732711" "unprognostic (2.80e-1)" "unprognostic (2.16e-1)" "unprognostic (2.65e-1)" "unprognostic (5.30e-2)" "unprognostic (1.73e-1)" "unprognostic (2.40e-2)" "prognostic unfavorable (2.29e-5)" "unprognostic (1.13e-2)" "unprognostic (2.58e-3)" "unprognostic (1.11e-1)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.58e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.92e-2)" "unprognostic (1.71e-1)" "unprognostic (1.89e-2)" "unprognostic (4.12e-1)" 0.8 1.1 0.1 4.4 0.1 28.8 1.8 0.0 0.3 1.3 0.5 5.8 6.1 1.8 0.1 8.6 0.6 0.7 0.4 0.3 0.0 0.4 0.9 0.9 8.5 0.3 0.5 0.7 0.3 0.2 0.1 3.1 0.3 0.5 5.7 1.0 1.4 0.1 0.2 6.2 4.3 2.5 0.2 2.4 2.6 10.5 0.5 33.0 0.4 0.6 10.0 1.4 2.6 0.3 123.7 68.4 144.3 75.8 5.4 7.2 56.3 74.6 30.3 43.9 42.8 54.6 74.1 116.3 43.1 41.7 39.8 74.7 89.9 49.2 74.1 102.6 56.6 96.0 111.4 78.6 0.8 137.0 50.5 2.7 3.8 63.3 72.3 12.7 46.9 52.6 88.4 68.0 79.4 47.0 81.5 54.3 127.9 36.8 30.0 85.7 203.7 38.6 43.2 30.3 67.4 91.2 100.7 66.2 38.9 76.2 79.1 51.9 61.7 78.9 92.2 66.2 155.9 51.6 60.7 108.7 34.4 96.7 71.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.3 0.3 0.0 0.3 0.5 0.3 0.2 0.5 0.3 3.0 0.0 3.1 0.0 11.5 9.3 2.8 11.2 3.4 4.7 10.0 6.7 1.9 1.5 9.9 0.0 0.0 53.3 10.8 19.1 0.0 2.0 84.4 30.1 19.3 12.4 0.0 268.7 1.3 0.4 78.8 19.0 32.1 25.2 1.3 165.8 8.9 2.6 32.2 1.7 0.8 20.1 14.2 16.6 6.6 19.8 1.2 16.2 1.8 1.0 0.7 1.4 5.2 0.0 0.1 0.5 1.1 3.0 25.9 2.3 2.1 0.1 16.7 3.1 0.0 8.3 23.9 107.5 107.1 44.6 5.5 5.1 23.3 11.7 41.3 3.7 CENPH ENSG00000153044 "Centromere protein H" Q9H3R5 5 69189574-69210357 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 33.8;testis: 29.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 74.5;Spermatocytes: 222.7;Spermatogonia: 222.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA036494 Approved Supported "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli rim" "Mitotic chromosome" "HPA036494: AB_10673354" "unprognostic (1.49e-1)" "prognostic favorable (6.86e-4)" "unprognostic (1.73e-2)" "unprognostic (3.16e-2)" "unprognostic (2.32e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (5.22e-5)" "unprognostic (6.14e-3)" "unprognostic (6.85e-2)" "prognostic favorable (2.50e-4)" "unprognostic (4.21e-2)" "unprognostic (8.80e-2)" "prognostic unfavorable (5.11e-15)" "unprognostic (1.17e-1)" "unprognostic (3.94e-1)" "unprognostic (2.58e-1)" "unprognostic (2.20e-1)" 4.2 2.0 1.4 7.5 1.7 33.8 7.7 1.7 2.0 3.9 1.0 7.4 6.5 4.5 2.1 7.5 4.0 1.8 4.0 1.5 1.6 1.6 3.6 2.8 17.7 1.6 1.5 3.9 1.5 2.0 1.4 5.2 1.6 3.3 8.1 2.5 2.9 2.3 4.0 9.2 5.9 3.7 1.4 5.2 3.7 29.7 1.6 18.5 2.5 4.0 18.8 3.8 4.4 2.2 64.6 19.4 88.6 70.2 5.8 18.3 48.0 31.2 32.6 66.9 71.8 26.5 79.6 138.9 36.6 18.1 39.1 47.0 59.0 70.4 85.1 42.7 41.4 32.7 32.5 26.4 2.0 47.1 32.1 7.1 14.6 43.6 47.7 18.9 23.2 73.7 58.7 53.3 52.2 35.6 152.4 67.3 78.1 20.7 17.0 93.2 118.2 108.2 21.1 22.9 61.6 81.9 34.6 22.8 27.5 47.7 31.9 31.4 11.4 33.4 56.1 44.5 78.7 65.5 106.3 111.8 51.1 94.2 64.7 1.0 2.0 3.0 4.7 3.5 7.7 13.3 7.9 6.0 3.1 14.1 9.9 8.6 0.4 8.6 4.2 6.7 9.7 4.8 1.4 1.7 1.7 2.0 1.5 1.6 1.6 1.5 1.6 1.4 1.6 2.2 4.8 0.0 2.6 1.0 18.3 36.7 17.7 17.4 9.6 3.4 10.8 11.7 3.3 4.3 7.1 0.0 0.0 37.4 9.2 5.1 0.0 12.3 26.5 5.5 5.1 6.9 1.2 74.5 1.3 9.1 49.0 7.4 2.6 4.8 5.1 22.4 4.6 1.1 17.0 0.0 1.1 9.5 12.2 7.5 18.2 22.5 3.7 6.3 8.8 1.0 4.3 7.3 6.2 1.0 0.9 7.0 2.5 4.9 14.4 6.9 1.4 3.4 10.8 3.5 19.7 6.4 9.3 222.7 222.8 12.1 19.2 10.0 12.0 6.9 15.9 15.2 CENPV "CENP-V, p30, PRR6" ENSG00000166582 "Centromere protein V" Q7Z7K6 17 16342534-16353656 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 100.4;Spermatogonia: 124.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.3;memory B-cell: 1.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 106.4;JURKAT: 105.1;NTERA-2: 103.4" "Low region specificity" "Detected in all" "HPA042529, HPA042616" Enhanced Approved Nucleoplasm,Midbody,Cytosol Yes No "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Midbody, Cytosol" "HPA042529: AB_10793882, HPA042616: AB_10794050" "unprognostic (7.64e-2)" "unprognostic (4.41e-2)" "unprognostic (5.92e-2)" "unprognostic (9.66e-3)" "unprognostic (1.16e-1)" "unprognostic (1.32e-1)" "unprognostic (2.24e-1)" "unprognostic (6.47e-2)" "unprognostic (1.21e-1)" "unprognostic (4.00e-2)" "unprognostic (7.73e-3)" "unprognostic (7.93e-2)" "unprognostic (4.09e-3)" "unprognostic (2.58e-1)" "unprognostic (1.89e-2)" "unprognostic (2.54e-2)" "unprognostic (3.60e-3)" 4.0 4.7 11.7 0.6 11.3 5.1 4.6 9.3 11.7 4.4 7.1 9.1 9.8 5.9 3.5 0.5 6.6 1.3 5.6 11.9 13.2 3.4 10.7 2.6 1.2 11.6 11.0 6.2 4.0 3.9 7.0 1.2 10.0 3.1 8.0 4.0 1.5 4.0 21.1 0.8 10.6 4.0 11.6 1.1 13.2 10.3 11.4 17.1 2.4 9.5 1.2 4.2 1.7 11.9 10.7 20.4 106.4 53.4 3.0 2.7 18.2 8.7 8.6 26.5 20.0 20.5 4.7 42.5 17.0 6.5 4.9 3.2 69.3 0.6 16.8 0.0 85.9 10.1 5.0 41.1 29.2 10.1 0.0 7.6 2.8 31.6 18.7 3.0 15.2 105.1 17.4 0.0 8.0 1.8 80.2 34.2 103.4 69.1 0.0 57.1 4.1 4.9 6.1 15.4 56.8 43.9 22.2 0.3 5.2 48.6 0.3 24.8 1.0 0.0 8.6 1.2 0.0 0.0 0.0 24.9 0.0 14.0 0.6 0.0 0.0 1.3 0.1 0.0 0.0 1.4 0.0 0.0 0.2 0.1 0.3 0.3 0.0 0.0 0.0 0.3 0.0 0.0 11.7 11.3 9.3 11.7 11.9 13.2 11.6 11.0 10.0 11.6 11.4 11.9 13.3 0.0 2.7 3.9 13.7 1.0 29.7 0.5 4.6 40.0 22.5 31.6 4.2 30.0 4.4 1.8 4.2 19.6 19.6 43.0 31.3 7.5 16.3 2.6 32.4 5.0 39.4 12.6 18.9 23.3 22.1 9.2 59.1 2.7 5.7 39.7 1.8 50.1 6.0 11.8 21.8 63.0 0.0 1.4 0.7 9.0 8.7 4.6 8.8 3.7 2.0 45.9 13.4 19.6 11.7 17.8 83.9 11.7 10.7 38.0 100.4 43.5 2.5 15.0 26.3 4.2 17.9 81.6 124.2 2.5 2.6 6.4 10.7 8.7 78.9 45.0 CEP112 "CCDC46, MGC33887" ENSG00000154240 "Centrosomal protein 112" Q8N8E3 17 65635537-66192133 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 49.0" "Group enriched" "Detected in many" 8 "Early spermatids: 1061.4;Late spermatids: 1606.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 32.0;RH-30: 75.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069724 Approved "Nucleoplasm,Midbody ring,Centrosome,Cytosol" Yes NA "Cluster 11: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Centrosome" "Midbody ring, Cytosol" "HPA069724: " "unprognostic (9.35e-2)" "unprognostic (3.08e-2)" "unprognostic (2.93e-1)" "unprognostic (6.21e-2)" "unprognostic (1.06e-2)" "unprognostic (4.11e-3)" "unprognostic (1.43e-2)" "unprognostic (7.99e-2)" "unprognostic (4.48e-3)" "unprognostic (3.37e-2)" "unprognostic (1.39e-3)" "unprognostic (3.50e-2)" "unprognostic (4.46e-3)" "unprognostic (1.02e-2)" "unprognostic (1.26e-1)" "unprognostic (3.52e-2)" "unprognostic (2.71e-1)" 11.3 3.9 5.0 2.7 5.4 1.7 9.5 7.1 5.8 8.3 11.9 7.8 2.0 8.5 8.2 4.3 8.3 7.0 8.0 7.4 5.1 5.6 3.2 7.4 2.5 5.8 5.7 8.2 4.6 8.7 8.3 7.2 4.2 7.2 3.1 25.4 3.0 7.9 8.8 3.3 2.9 8.0 3.4 8.8 4.2 49.0 5.5 2.8 7.1 14.0 1.7 5.4 5.9 3.4 5.0 10.5 13.3 3.8 6.9 14.0 0.4 4.5 7.7 5.5 5.0 1.5 2.0 1.6 4.3 9.8 15.5 0.6 2.9 2.9 7.8 2.6 4.8 0.3 4.7 1.9 2.9 0.6 0.2 8.4 4.8 5.2 1.6 11.0 16.8 2.7 0.3 5.0 32.0 0.7 5.3 0.4 1.3 1.1 4.4 1.5 75.9 0.4 6.0 0.3 3.5 7.4 4.7 0.5 3.6 11.4 3.8 0.4 7.9 14.3 8.2 3.9 6.7 2.3 2.1 0.2 4.4 0.2 5.3 1.3 0.4 0.4 0.3 0.2 0.6 0.3 0.8 0.3 0.2 0.8 0.5 0.3 1.3 0.8 0.2 1.4 0.5 0.1 5.0 5.4 7.1 5.8 7.4 5.1 5.8 5.7 4.2 3.4 5.5 3.4 39.7 9.6 35.8 83.6 1.1 2.5 2.9 2.2 2.2 36.7 2.7 5.5 28.3 4.3 15.3 1.8 20.9 0.7 0.8 1.5 1.9 7.4 1061.4 15.3 15.8 25.4 1.8 0.4 117.4 4.7 1.5 12.4 1.5 3.3 2.5 11.2 19.2 0.2 1.8 1.7 103.8 0.3 0.0 0.8 11.3 1606.0 24.8 2.3 14.2 99.3 0.0 14.7 1.0 29.7 6.6 4.4 0.5 19.9 0.4 1.5 0.0 4.3 23.7 154.3 13.1 43.7 12.5 40.6 16.5 2.4 1.6 0.1 2.5 3.1 1.5 1.3 CEP131 "AZ1, AZI1, KIAA1118" ENSG00000141577 "Centrosomal protein 131" Q9UPN4 17 81189593-81222999 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cilium biogenesis/degradation, Differentiation, Spermatogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatogonia: 20.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024019 Approved Supported "Microtubules,Cytokinetic bridge,Centriolar satellite" Yes No "Cluster 14: Monocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 20: HeLa - Mitochondria" "Cluster 43: Cardiomyocytes - Nuclear processes" Microtubules "Cytokinetic bridge, Centriolar satellite" "HPA024019: AB_1845227" "unprognostic (1.56e-2)" "unprognostic (1.09e-2)" "unprognostic (2.41e-1)" "unprognostic (2.31e-1)" "unprognostic (2.80e-1)" "unprognostic (3.26e-2)" "prognostic unfavorable (9.68e-5)" "unprognostic (3.43e-1)" "unprognostic (7.62e-2)" "unprognostic (2.43e-1)" "unprognostic (1.33e-3)" "unprognostic (7.04e-2)" "unprognostic (8.82e-3)" "unprognostic (1.36e-2)" "unprognostic (8.48e-2)" "unprognostic (2.66e-1)" "unprognostic (7.32e-3)" 9.1 8.6 6.7 5.2 6.4 10.2 10.3 7.8 10.0 14.7 7.5 9.8 4.6 11.4 0.9 9.1 11.5 2.0 16.8 6.5 5.8 11.7 6.8 10.7 7.9 6.8 6.2 12.8 10.1 2.2 15.4 4.1 6.2 12.0 0.8 1.8 9.3 2.1 11.1 10.5 10.3 1.6 5.7 19.0 9.9 28.2 6.7 3.5 10.3 2.0 2.2 10.4 10.7 6.8 21.1 20.0 10.6 19.4 1.7 2.7 33.6 14.4 2.5 10.3 7.9 23.8 10.5 14.8 8.0 3.5 6.3 14.9 3.1 7.0 2.5 6.2 26.8 14.3 32.7 41.3 2.9 12.5 30.6 2.3 4.6 7.5 2.1 3.3 7.3 15.6 10.6 8.5 2.7 23.5 29.0 24.3 9.5 6.1 17.7 29.0 12.1 6.1 3.9 18.4 24.2 27.2 18.5 11.4 18.0 3.9 17.2 12.3 10.0 18.6 32.1 16.7 19.2 22.0 4.0 11.3 9.6 10.7 13.5 2.1 0.8 0.5 1.2 2.3 0.3 2.9 0.7 1.1 1.8 1.7 1.1 0.8 1.3 1.0 4.6 2.0 0.1 0.8 6.7 6.4 7.8 10.0 6.5 5.8 6.8 6.2 6.2 5.7 6.7 6.8 6.5 0.0 4.4 5.5 6.6 0.0 3.4 0.0 3.4 5.8 3.3 4.4 13.4 2.8 1.3 3.7 6.2 8.7 4.8 5.6 0.0 4.5 14.0 8.4 3.5 6.0 6.7 5.7 2.1 3.7 7.2 6.9 6.6 2.8 15.9 9.3 2.5 1.7 5.2 5.0 2.9 5.1 0.0 1.9 0.0 17.9 9.6 3.6 0.0 1.0 1.3 6.0 7.2 2.5 2.8 5.2 0.8 3.0 4.4 1.2 1.8 1.4 3.6 6.9 0.0 4.3 5.7 14.7 20.5 3.7 0.0 6.0 3.5 8.4 7.9 2.7 CEP192 "FLJ10352, KIAA1569, PPP1R62" ENSG00000101639 "Centrosomal protein 192" Q8TEP8 18 12991362-13125052 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 67.6;Excitatory neurons: 94.4;Inhibitory neurons: 91.3;Oligodendrocyte precursor cells: 76.9;Oligodendrocytes: 90.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039392, HPA040503" Uncertain Supported Centrosome,Cytosol Yes No "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Centrosome, Cytosol" "HPA039392: AB_10697549, HPA040503: AB_10670919" "unprognostic (6.94e-2)" "unprognostic (1.38e-1)" "unprognostic (1.23e-1)" "unprognostic (5.89e-2)" "unprognostic (1.64e-1)" "unprognostic (2.04e-2)" "unprognostic (1.13e-3)" "unprognostic (6.87e-3)" "unprognostic (5.83e-3)" "unprognostic (2.20e-2)" "unprognostic (9.00e-2)" "unprognostic (6.61e-2)" "unprognostic (1.28e-1)" "unprognostic (7.89e-2)" "unprognostic (2.39e-1)" "unprognostic (4.54e-2)" "unprognostic (1.66e-3)" 2.9 2.2 5.0 4.6 7.6 10.8 4.9 9.8 5.2 4.7 0.0 4.5 4.0 6.4 3.9 3.7 4.9 5.7 3.6 4.1 2.4 2.8 2.9 4.4 6.9 4.1 4.7 9.9 4.6 4.7 2.5 4.6 3.6 4.0 5.4 6.8 4.1 3.5 1.8 3.5 4.7 4.6 3.4 5.2 4.7 9.3 5.0 11.6 5.5 3.9 5.6 4.1 2.5 9.7 13.5 7.2 19.1 10.1 8.1 12.6 6.1 9.2 12.1 14.3 15.1 9.9 5.8 15.2 6.1 9.4 10.4 6.4 16.7 8.8 16.8 6.0 6.0 13.8 11.3 5.2 4.3 22.2 10.2 8.8 3.2 12.0 10.9 8.2 11.9 10.7 19.3 9.9 11.3 6.8 19.2 9.6 6.1 24.9 4.4 16.3 14.9 7.9 4.9 13.6 13.9 7.8 14.7 7.2 4.4 9.0 5.8 11.3 12.1 11.2 26.2 12.9 12.8 6.6 10.1 17.0 7.2 9.9 11.0 0.4 0.6 0.5 0.9 0.4 0.7 0.5 0.6 0.6 0.3 1.3 0.6 1.0 0.6 0.2 1.7 0.5 0.5 0.3 5.0 7.6 9.8 5.2 4.1 2.4 4.1 4.7 3.6 3.4 5.0 9.7 13.3 9.6 12.8 67.6 11.4 1.9 3.9 4.3 5.2 13.1 6.4 5.8 28.7 4.3 9.3 7.3 22.9 5.3 13.7 7.6 0.0 4.7 23.3 11.0 11.8 8.5 0.0 18.7 94.4 3.6 3.3 10.5 15.8 12.1 2.5 40.9 8.2 6.5 4.6 11.8 91.3 8.7 4.1 10.1 3.9 14.2 10.2 10.1 1.8 62.8 15.3 6.5 14.4 76.9 90.6 4.8 5.7 13.9 15.0 5.5 4.5 1.2 8.0 17.8 26.3 11.3 8.1 33.5 24.0 8.5 3.1 1.9 12.3 60.6 8.0 7.6 CEP55 "C10orf3, CT111, FLJ10540" ENSG00000138180 "Centrosomal protein 55" Q53EZ4 10 93496612-93529092 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 27.4;testis: 21.7" "Cell type enhanced" "Detected in many" "Early spermatids: 29.4;Extravillous trophoblasts: 17.1;Granulosa cells: 19.8;Spermatocytes: 77.3;Spermatogonia: 17.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 8 "T-reg: 1.3" "Lineage enriched" "Detected in single" 14 "T-cells: 1.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA023430 Approved Approved "Plasma membrane,Midbody,Centriolar satellite" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Centriolar satellite" Midbody "HPA023430: AB_10960212" "unprognostic (9.85e-2)" "unprognostic (1.12e-2)" "unprognostic (1.04e-1)" "unprognostic (1.29e-1)" "unprognostic (5.15e-2)" "unprognostic (4.26e-2)" "prognostic unfavorable (3.20e-9)" "prognostic unfavorable (1.45e-4)" "unprognostic (1.50e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.66e-5)" "unprognostic (3.99e-2)" "prognostic unfavorable (0.00e+0)" "prognostic favorable (3.15e-4)" "unprognostic (7.86e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" 1.3 0.6 0.0 7.6 0.0 5.0 1.4 0.0 0.2 1.7 0.0 7.0 6.7 1.4 0.1 7.3 0.4 1.4 0.3 0.0 0.1 0.3 0.6 1.3 14.7 0.1 0.3 0.2 0.2 0.2 0.3 3.5 0.2 0.3 8.8 0.0 1.2 0.3 0.1 4.5 6.3 5.2 0.0 2.4 4.6 21.7 0.4 27.4 0.5 0.2 15.5 3.1 2.3 0.1 208.5 81.5 53.0 67.7 5.8 12.0 29.6 112.4 78.2 103.5 106.4 87.2 108.6 55.4 48.2 72.8 69.6 115.4 64.8 54.8 123.4 167.2 33.7 21.0 49.2 29.9 0.6 36.3 46.3 2.8 3.8 110.6 133.5 30.7 97.1 89.9 19.3 101.8 118.5 48.3 96.3 54.8 20.9 64.2 58.8 41.3 86.9 30.3 47.1 25.5 21.7 30.7 86.3 26.3 64.9 40.1 68.9 36.4 61.4 65.3 90.6 90.5 186.7 45.1 66.1 66.8 51.0 134.8 59.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.3 0.2 0.0 0.4 0.1 0.2 0.0 1.3 0.0 2.7 3.6 0.9 1.9 0.0 0.0 1.8 2.0 0.4 2.8 0.2 0.0 0.0 7.7 0.9 3.3 0.0 0.6 29.4 1.7 2.0 1.5 0.0 2.5 0.5 0.2 17.1 2.3 8.2 3.6 0.0 19.8 2.2 0.3 12.9 0.0 0.3 4.5 4.1 7.0 5.1 8.2 0.3 5.1 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.3 0.0 0.4 14.8 1.1 0.4 0.0 0.2 0.0 0.0 0.5 4.5 77.3 17.3 16.1 1.3 1.5 4.3 1.6 7.9 1.7 CFAP53 "CCDC11, FLJ32743" ENSG00000172361 "Cilia and flagella associated protein 53" Q96M91 18 50227193-50266495 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Ciliopathy, Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "fallopian tube: 28.5;testis: 79.6" "Group enriched" "Detected in many" 14 "Early spermatids: 809.6;Endometrial ciliated cells: 331.5;Late spermatids: 528.4;Respiratory ciliated cells: 216.5;Spermatocytes: 481.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-HME1: 4.7" "HPA041069, HPA066142" Enhanced Approved Midbody Yes No "Cluster 26: Non-specific - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 49: Ciliated cells - Cilium organization" Midbody "HPA041069: AB_10805835, HPA066142: AB_2732739" "unprognostic (1.73e-2)" "unprognostic (1.13e-2)" "unprognostic (5.83e-2)" "unprognostic (3.12e-3)" "unprognostic (3.31e-2)" "unprognostic (1.19e-1)" "unprognostic (3.64e-4)" "unprognostic (2.90e-2)" "unprognostic (3.68e-2)" "unprognostic (9.75e-3)" "unprognostic (1.65e-1)" "unprognostic (1.04e-1)" "prognostic favorable (5.85e-4)" "unprognostic (3.22e-1)" "unprognostic (1.17e-2)" "unprognostic (4.34e-3)" "unprognostic (4.61e-3)" 0.3 1.2 3.0 0.4 3.4 0.7 1.1 5.0 3.2 2.0 8.5 0.5 0.2 1.1 5.7 0.4 28.5 0.7 0.5 3.1 3.7 2.7 0.4 3.3 0.3 6.8 7.8 1.0 1.1 2.5 3.3 0.3 6.0 0.9 0.2 3.5 0.6 1.2 2.3 1.0 0.4 0.3 5.3 0.4 0.5 79.6 3.4 0.5 3.9 0.4 0.2 0.6 0.6 5.0 1.2 0.8 0.5 1.0 0.7 1.3 0.9 0.2 0.1 0.1 0.2 0.1 1.0 0.7 0.7 0.3 0.3 0.5 0.3 0.5 0.2 0.5 0.7 0.3 0.3 0.1 0.3 0.5 0.4 0.4 2.0 0.5 4.7 1.1 0.3 1.9 1.4 0.4 0.3 1.2 1.2 0.2 0.2 0.2 0.5 0.1 0.2 1.0 1.4 0.0 0.8 0.6 0.1 0.0 0.4 1.3 0.6 0.1 0.0 0.7 0.5 0.4 0.4 2.1 0.8 0.1 0.7 0.5 0.1 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.2 0.1 0.0 0.2 0.0 0.2 0.2 0.0 3.0 3.4 5.0 3.2 3.1 3.7 6.8 7.8 6.0 5.3 3.4 5.0 0.6 6.4 4.2 2.6 0.6 0.0 2.0 0.0 1.8 4.3 4.7 3.8 0.4 0.0 21.1 9.2 8.4 1.7 0.2 0.3 9.8 3.4 809.6 331.5 3.8 1.4 0.0 0.4 3.8 0.6 0.5 2.2 2.6 7.9 1.3 1.4 1.8 1.0 0.4 1.7 4.4 0.2 0.0 0.0 0.0 528.4 8.4 1.3 0.0 2.8 1.0 2.7 1.0 3.0 6.5 0.8 0.1 5.7 0.9 1.3 0.8 20.5 216.5 10.5 6.6 2.1 0.7 481.5 32.5 1.3 0.0 0.7 1.0 1.7 0.4 1.1 CFAP99 ENSG00000206113 "Cilia and flagella associated protein 99" 4 2418974-2462942 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 4.8;choroid plexus: 5.8;fallopian tube: 3.9;retina: 1.5;testis: 5.3" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 4.2;Early spermatids: 11.6;Endometrial ciliated cells: 13.6;Late spermatids: 11.2;Rod photoreceptor cells: 5.5;Spermatocytes: 14.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA071642 Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 49: Ciliated cells - Cilium organization" "Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA071642: " "unprognostic (7.54e-3)" "unprognostic (6.46e-3)" "unprognostic (1.12e-1)" "unprognostic (2.31e-3)" "unprognostic (2.68e-2)" "unprognostic (1.49e-1)" "unprognostic (3.12e-2)" "unprognostic (5.22e-2)" "unprognostic (1.89e-1)" "unprognostic (8.14e-2)" "unprognostic (7.93e-5)" "unprognostic (1.15e-1)" "unprognostic (5.97e-3)" "unprognostic (1.92e-2)" "unprognostic (1.36e-1)" "unprognostic (6.94e-2)" "unprognostic (3.49e-1)" 0.0 0.8 0.5 0.0 0.5 0.0 0.0 0.8 0.3 0.2 5.8 0.0 0.0 0.2 0.1 0.0 3.9 0.0 0.0 0.9 0.8 0.2 0.1 0.6 0.0 3.2 4.8 0.0 0.3 0.0 0.8 0.0 1.8 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.1 5.3 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.8 0.3 0.9 0.8 3.2 4.8 1.8 2.0 1.0 0.6 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.2 0.0 1.8 3.7 4.2 0.0 0.0 0.0 0.0 0.2 11.6 13.6 0.2 0.1 0.0 0.0 1.2 0.6 0.1 0.1 0.0 0.5 0.0 0.3 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 11.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.2 0.2 1.5 2.9 5.5 0.0 0.0 0.0 14.0 1.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 CHAMP1 "C13orf8, CAMP, CHAMP, ZNF828" ENSG00000198824 "Chromosome alignment maintaining phosphoprotein 1" Q96JM3 13 114314482-114337626 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006623, HPA008900" Enhanced Enhanced "Nucleoplasm,Nuclear bodies,Midbody ring" Yes No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies, Midbody ring" "HPA006623: AB_1845548, HPA008900: AB_1845547" "unprognostic (6.60e-2)" "unprognostic (1.12e-1)" "unprognostic (1.99e-2)" "unprognostic (1.76e-1)" "unprognostic (4.55e-2)" "unprognostic (1.67e-1)" "unprognostic (3.89e-3)" "unprognostic (2.07e-1)" "unprognostic (9.43e-2)" "unprognostic (1.13e-1)" "unprognostic (4.38e-2)" "unprognostic (1.13e-2)" "unprognostic (4.40e-2)" "unprognostic (3.50e-2)" "unprognostic (3.67e-1)" "unprognostic (4.62e-2)" "unprognostic (2.40e-1)" 9.9 7.1 3.4 9.8 3.3 14.2 9.5 6.6 5.2 8.1 3.8 8.7 10.0 8.5 8.0 6.4 9.8 7.6 6.2 3.0 4.3 8.9 15.2 8.9 15.7 2.7 3.4 12.1 15.4 9.3 3.6 9.9 3.4 10.0 9.9 9.1 8.4 9.3 7.9 9.2 8.0 10.1 2.3 9.6 7.7 6.9 2.7 16.5 10.7 9.7 17.3 7.5 4.4 3.1 36.9 15.8 56.6 24.2 20.1 30.9 24.3 38.2 32.0 35.6 39.4 23.5 22.0 75.2 15.1 30.0 22.3 23.0 41.8 30.6 52.7 29.8 50.0 49.7 21.8 20.7 22.5 73.3 28.3 30.4 18.8 27.8 27.3 12.6 17.4 25.8 32.1 20.3 46.1 14.6 48.6 21.4 43.1 45.2 20.2 48.1 26.9 26.0 27.0 22.2 27.5 32.8 22.2 49.2 36.7 39.1 28.2 61.3 19.3 19.5 30.8 20.7 23.6 25.7 27.9 80.4 38.6 42.7 38.1 7.5 3.3 4.4 3.7 4.0 4.6 5.4 3.3 3.7 3.9 5.8 2.6 3.0 0.8 3.5 6.6 12.5 2.4 2.1 3.4 3.3 6.6 5.2 3.0 4.3 2.7 3.4 3.4 2.3 2.7 3.1 11.2 9.6 9.6 3.6 13.9 3.3 6.6 7.6 10.8 12.5 11.3 10.8 5.7 11.5 4.1 12.9 4.2 14.2 18.1 9.3 13.7 11.7 1.0 8.5 14.8 10.9 10.8 24.4 6.1 11.4 18.1 11.5 10.2 8.3 10.1 13.1 13.9 21.6 21.7 15.2 7.8 12.5 6.1 20.7 7.8 1.6 11.8 13.0 12.4 7.5 18.4 8.8 17.5 4.0 8.0 10.9 7.8 11.3 17.6 13.2 12.5 17.0 7.6 10.9 6.6 11.7 10.5 10.6 20.7 13.1 3.8 7.9 11.4 12.4 11.4 3.5 CHMP1B "C18orf2, CHMP1.5, Vps46B" ENSG00000255112 "Charged multivesicular body protein 1B" Q7LBR1 18 11851413-11854444 "Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "skeletal muscle: 361.4" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 514.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061997, HPA062896" Supported Approved Nucleoplasm,Midbody Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" Midbody Nucleoplasm "HPA061997: AB_2684653, HPA062896: AB_2684898" "unprognostic (6.73e-2)" "unprognostic (5.35e-2)" "unprognostic (1.09e-2)" "unprognostic (6.74e-3)" "unprognostic (1.80e-1)" "unprognostic (1.35e-3)" "unprognostic (1.44e-1)" "unprognostic (8.44e-3)" "unprognostic (1.90e-1)" "unprognostic (9.44e-3)" "unprognostic (2.37e-3)" "unprognostic (9.20e-2)" "prognostic favorable (7.37e-8)" "unprognostic (1.88e-2)" "unprognostic (1.59e-1)" "unprognostic (2.53e-2)" "unprognostic (1.92e-1)" 43.3 35.7 24.5 36.2 25.9 61.2 29.0 19.6 25.4 25.6 30.0 39.1 38.7 28.3 26.2 39.1 24.8 39.3 40.7 25.9 25.6 33.1 31.1 29.7 29.9 21.9 23.2 29.6 24.8 39.9 29.3 27.8 22.6 27.8 37.5 17.6 29.5 35.0 361.4 40.4 48.8 23.6 20.3 30.2 30.5 14.0 24.0 46.0 52.2 53.2 24.8 49.5 23.8 23.6 30.0 28.8 36.5 31.1 46.9 32.7 52.9 31.4 52.6 21.0 27.9 37.5 29.4 18.5 45.9 34.2 35.0 25.0 16.8 43.7 18.5 17.2 20.8 13.5 43.6 31.1 34.6 51.7 22.3 47.7 92.5 23.5 53.9 46.8 30.7 41.6 23.1 23.4 33.3 37.3 36.1 39.6 15.3 94.9 14.3 18.4 18.8 32.1 56.5 40.5 35.5 35.5 53.1 24.7 50.5 33.9 20.2 47.2 45.2 46.7 24.5 37.3 34.0 27.8 34.3 23.5 43.3 23.8 22.7 32.5 38.8 66.7 15.4 35.7 14.3 14.7 14.3 18.5 30.2 14.7 17.6 16.4 77.9 18.3 36.6 26.7 21.5 29.2 24.5 25.9 19.6 25.4 25.9 25.6 21.9 23.2 22.6 20.3 24.0 23.6 71.2 67.3 47.0 0.0 152.9 419.6 141.8 291.8 216.9 30.5 71.3 59.4 21.7 52.9 157.7 132.4 8.4 135.9 171.0 281.4 60.7 123.0 80.4 146.6 110.2 69.9 143.8 40.4 0.0 80.3 144.4 99.3 70.8 298.3 149.9 38.4 52.8 44.1 118.0 28.6 0.0 104.6 111.9 139.9 440.8 42.6 37.9 354.5 158.3 0.0 102.1 32.2 78.2 0.0 0.0 134.0 393.7 37.2 21.8 93.9 179.2 139.1 84.8 16.8 78.9 61.2 94.5 16.0 21.1 177.1 514.7 253.2 135.5 43.9 96.8 252.2 CHMP4C "MGC22825, Shax3, VPS32C" ENSG00000164695 "Charged multivesicular body protein 4C" Q96CF2 8 81732448-81759515 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.8" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 71.6;Pancreatic endocrine cells: 78.7;Proximal enterocytes: 80.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 37.2;CAPAN-2: 41.5;hTCEpi: 51.4;hTERT-HME1: 41.6;OE19: 73.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA023763, HPA023799" Enhanced Approved "Microtubules,Cytokinetic bridge" Yes NA "Cluster 48: NK-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "Microtubules, Cytokinetic bridge" "HPA023763: , HPA023799: AB_1846670" "unprognostic (3.98e-2)" "unprognostic (6.75e-3)" "unprognostic (1.58e-1)" "unprognostic (5.19e-2)" "unprognostic (3.12e-2)" "unprognostic (2.45e-2)" "unprognostic (5.75e-2)" "prognostic unfavorable (9.33e-5)" "unprognostic (7.54e-2)" "unprognostic (8.08e-2)" "prognostic unfavorable (6.99e-5)" "unprognostic (1.99e-2)" "prognostic favorable (1.96e-6)" "unprognostic (3.29e-3)" "unprognostic (4.95e-1)" "unprognostic (2.67e-1)" "prognostic favorable (6.45e-4)" 1.7 5.8 1.2 2.1 1.3 1.2 16.6 1.6 1.3 7.5 2.8 16.2 41.8 2.3 5.8 22.6 8.7 8.0 3.6 1.1 1.0 13.9 7.7 7.2 0.5 1.5 1.4 0.5 20.1 15.8 10.1 5.8 1.5 10.0 14.8 0.2 28.1 7.6 0.2 29.1 31.7 0.8 1.1 8.5 23.7 1.1 1.4 1.9 17.5 0.5 5.2 9.7 14.2 2.0 37.2 7.6 0.0 0.2 0.0 0.0 16.6 1.9 2.2 0.1 0.0 14.3 41.5 0.1 28.8 0.0 6.4 22.1 0.2 15.7 0.0 0.0 17.9 0.7 9.9 13.6 0.8 0.1 0.1 0.0 51.4 0.0 41.6 15.3 0.0 0.0 10.0 12.4 0.0 18.4 0.1 0.3 0.1 73.1 14.9 0.1 0.0 8.3 36.3 22.0 7.9 0.1 9.9 16.3 0.1 8.5 23.9 0.2 0.0 0.1 8.9 0.1 0.2 6.5 4.3 0.2 0.0 0.1 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.4 1.9 0.0 0.1 0.0 0.1 1.2 1.3 1.6 1.3 1.1 1.0 1.5 1.4 1.5 1.1 1.4 2.0 5.3 25.6 21.5 0.0 3.2 4.6 35.4 17.1 18.2 0.0 27.2 29.3 4.1 21.5 22.4 5.5 0.0 40.2 0.6 42.0 25.4 47.4 0.4 18.6 2.9 4.0 9.1 1.7 0.1 71.6 38.9 1.0 25.5 31.0 1.3 6.5 4.2 7.6 4.4 0.0 0.1 36.4 12.2 0.3 0.7 1.3 0.0 0.9 8.8 1.0 0.0 0.0 1.0 0.0 0.1 78.7 52.8 0.0 5.7 28.9 80.4 22.6 19.1 0.0 0.0 0.2 7.0 0.3 0.7 25.0 17.5 44.5 1.3 0.1 34.4 33.6 CHMP5 "C9orf83, CGI-34, HSPC177, SNF7DC2, Vps60" ENSG00000086065 "Charged multivesicular body protein 5" Q9NZZ3 9 33264879-33282070 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033874, HPA042883, HPA056437" Enhanced Supported Microtubules,Midbody,Cytosol Yes No 22000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Microtubules, Cytosol" Midbody "CAB033874: AB_10608611, HPA042883: AB_2678212, HPA056437: AB_2683133" "unprognostic (1.10e-1)" "unprognostic (1.10e-1)" "unprognostic (9.08e-2)" "unprognostic (1.07e-1)" "unprognostic (2.32e-1)" "unprognostic (4.56e-2)" "unprognostic (3.87e-2)" "unprognostic (2.18e-2)" "unprognostic (4.71e-2)" "unprognostic (2.14e-3)" "unprognostic (7.94e-2)" "unprognostic (2.66e-1)" "prognostic favorable (2.87e-7)" "unprognostic (2.22e-1)" "unprognostic (9.59e-2)" "unprognostic (1.73e-1)" "unprognostic (7.31e-2)" 54.6 54.6 48.3 36.7 49.2 30.5 49.6 50.4 63.8 56.4 50.0 55.7 55.2 41.3 48.1 64.6 43.8 42.1 50.8 49.0 50.3 77.8 56.3 53.5 41.6 50.4 49.7 42.9 32.7 63.9 49.7 63.8 50.7 54.8 55.9 53.8 43.7 39.4 48.2 47.0 59.2 33.9 52.7 43.5 54.6 36.2 49.4 44.9 55.8 44.3 38.1 49.7 56.5 56.9 92.2 66.5 67.0 43.5 99.0 89.0 61.9 90.1 99.7 138.3 152.6 50.9 56.9 49.0 96.3 84.3 95.9 39.2 70.5 72.8 111.1 102.5 49.3 41.5 129.7 55.8 85.9 53.4 78.8 95.6 131.3 93.6 86.4 114.5 73.3 68.3 44.9 63.6 110.5 41.3 56.1 164.1 61.8 70.1 80.6 34.0 59.2 32.9 115.2 48.7 32.7 83.6 91.0 53.4 87.2 77.8 54.2 82.7 74.4 69.5 73.0 60.2 80.8 42.3 87.6 57.0 100.5 36.0 45.6 98.6 50.3 106.3 25.3 56.5 27.6 31.0 33.7 33.8 46.5 26.4 30.6 29.4 129.4 47.4 67.3 71.2 43.4 51.3 48.3 49.2 50.4 63.8 49.0 50.3 50.4 49.7 50.7 52.7 49.4 56.9 182.7 89.8 59.0 14.0 52.9 188.1 156.2 372.5 71.7 63.7 85.2 75.1 64.7 94.4 228.6 110.3 27.1 172.0 77.4 241.0 285.7 141.7 245.2 228.0 90.6 133.8 80.2 90.1 19.6 86.1 186.1 104.4 56.1 167.0 58.4 66.5 97.5 70.5 154.9 26.9 19.0 137.9 246.2 100.9 103.2 35.9 93.2 95.3 117.4 15.0 166.3 156.2 38.1 14.6 26.8 151.9 247.9 104.6 45.2 182.4 226.3 355.2 328.9 68.2 85.5 97.0 130.0 99.5 68.7 70.1 236.3 259.0 68.5 71.4 78.5 246.0 CHRNA2 ENSG00000120903 "Cholinergic receptor nicotinic alpha 2 subunit" Q15822 8 27459756-27479883 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "brain: 72.1;prostate: 29.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 6.5;Inhibitory neurons: 14.8;Prostatic glandular cells: 2.4;Theca cells: 3.4" "Cancer enriched" "Detected in single" 421 "prostate cancer: 30.2" "Region enhanced" "Detected in many" "thalamus: 72.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA048348 Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nucleoplasm, Cytokinetic bridge" "HPA048348: " "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (2.23e-2)" "unprognostic (3.19e-1)" "unprognostic (6.19e-2)" "unprognostic (6.29e-3)" "unprognostic (1.19e-2)" "unprognostic (2.13e-1)" "unprognostic (1.91e-1)" "unprognostic (7.60e-2)" "unprognostic (1.70e-1)" "unprognostic (1.47e-1)" 0.0 0.5 15.8 0.2 5.5 0.9 1.4 38.1 2.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 8.0 0.0 0.0 0.2 0.1 15.7 21.5 0.0 0.2 0.0 0.3 0.0 3.5 29.0 0.0 3.7 0.0 0.0 0.1 0.2 0.2 0.0 2.3 0.1 0.0 0.0 72.1 2.9 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 15.8 5.5 38.1 2.9 0.7 8.0 15.7 21.5 3.5 2.3 72.1 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.3 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 CISH "CIS, CIS-1, G18, SOCS" ENSG00000114737 "Cytokine inducible SH2 containing protein" Q9NSE2 3 50606489-50611774 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 60.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 38.5;Distal tubular cells: 58.7;Proximal tubular cells: 58.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 4 "HDLM-2: 316.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB034039, HPA040812" Approved Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 32: T-cells - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Microtubules "Cytokinetic bridge" "CAB034039: AB_2080282, HPA040812: AB_2677148" "unprognostic (2.36e-3)" "unprognostic (7.60e-3)" "unprognostic (2.89e-2)" "prognostic favorable (1.13e-5)" "unprognostic (8.54e-2)" "unprognostic (9.38e-2)" "prognostic favorable (6.98e-4)" "unprognostic (6.97e-3)" "unprognostic (3.84e-1)" "unprognostic (2.10e-1)" "prognostic favorable (9.65e-4)" "unprognostic (1.30e-2)" "prognostic favorable (3.53e-12)" "unprognostic (2.50e-1)" "unprognostic (1.76e-1)" "unprognostic (1.15e-1)" "unprognostic (1.78e-2)" 19.0 4.8 1.0 8.7 1.0 7.6 24.5 1.1 1.3 10.0 1.9 9.9 10.2 9.4 3.1 9.6 9.8 4.5 26.5 0.9 1.4 47.6 60.7 28.0 8.5 2.8 1.9 14.5 20.2 22.1 14.3 23.2 2.2 7.5 8.9 0.3 13.1 8.9 40.0 13.3 8.8 4.9 1.7 9.9 10.4 2.3 1.6 9.7 36.4 5.2 6.7 5.9 10.0 1.5 2.4 0.8 2.8 5.9 0.7 3.4 2.5 0.6 0.6 0.3 0.4 2.3 0.6 0.0 2.0 0.9 1.3 2.8 4.7 3.8 0.3 316.3 0.8 18.7 1.8 2.5 2.1 2.5 22.0 14.2 1.6 0.7 1.3 0.2 0.6 2.0 75.6 0.6 0.6 14.8 4.1 17.4 2.7 8.7 2.9 1.8 1.2 19.4 6.3 2.7 1.4 4.7 1.0 37.7 0.7 0.8 20.9 15.4 0.5 0.8 2.2 2.8 1.4 0.3 0.4 0.0 0.5 22.7 0.4 21.3 10.2 13.7 33.8 6.2 51.1 0.9 54.0 41.6 7.0 0.4 40.5 40.6 8.6 2.0 3.9 4.6 35.3 19.6 1.0 1.0 1.1 1.3 0.9 1.4 2.8 1.9 2.2 1.7 1.6 1.5 7.1 3.2 38.5 0.0 1.8 8.0 7.4 1.9 10.2 0.7 18.3 12.1 14.3 0.0 6.7 18.4 0.0 9.1 14.1 8.9 58.7 11.7 2.6 6.6 4.3 3.5 2.4 11.6 0.1 16.4 4.0 11.6 3.6 8.5 1.3 16.9 2.2 7.0 12.7 0.0 0.0 9.6 2.0 8.4 10.0 0.6 8.4 12.8 1.8 1.0 17.3 0.1 14.4 0.0 0.0 7.2 6.7 3.8 4.0 3.0 6.5 58.2 0.8 0.2 13.1 7.6 8.8 1.0 1.3 7.3 8.9 15.9 31.0 3.4 12.1 3.6 CKAP2 "FLJ10749, LB1, se20-10, TMAP" ENSG00000136108 "Cytoskeleton associated protein 2" Q8WWK9 13 52455429-52476628 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 67.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 122.9;Granulosa cells: 88.6;Spermatocytes: 151.7;Spermatogonia: 87.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA008410, HPA027821" Enhanced Enhanced "Microtubules,Mitotic spindle,Centrosome" Yes Yes "Cluster 6: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Microtubules, Mitotic spindle" Centrosome "HPA008410: AB_1846832, HPA027821: AB_10602208" "unprognostic (1.85e-1)" "unprognostic (2.09e-3)" "unprognostic (2.44e-2)" "unprognostic (4.07e-3)" "unprognostic (1.39e-2)" "unprognostic (5.03e-2)" "prognostic unfavorable (3.26e-5)" "unprognostic (3.38e-2)" "unprognostic (4.24e-2)" "unprognostic (1.69e-2)" "unprognostic (8.30e-2)" "unprognostic (6.60e-3)" "prognostic unfavorable (1.90e-5)" "unprognostic (2.01e-2)" "unprognostic (5.20e-2)" "unprognostic (5.97e-2)" "unprognostic (6.36e-2)" 6.0 6.4 3.7 10.0 3.8 67.8 5.7 10.8 5.3 3.2 1.3 8.9 12.1 5.1 4.4 10.4 3.5 4.1 6.0 3.2 4.1 5.1 4.0 5.3 19.4 4.8 3.8 3.2 1.5 4.3 4.5 10.6 5.2 5.6 9.5 7.7 4.6 4.2 2.9 13.9 9.5 8.5 3.3 9.4 5.4 32.5 3.7 33.7 6.3 3.4 20.2 7.2 5.0 3.1 77.6 40.0 155.7 76.4 19.7 19.5 39.6 124.7 70.7 137.4 87.2 59.7 92.3 142.5 19.3 89.2 65.7 86.2 107.6 61.7 188.8 103.0 90.4 129.8 42.6 41.4 8.6 129.7 50.4 14.5 24.6 64.5 83.3 41.2 84.0 62.0 55.3 58.1 152.8 36.0 91.2 64.8 92.2 116.6 42.4 86.2 88.6 62.6 42.1 40.9 47.6 62.4 68.9 49.0 37.1 78.7 54.4 61.7 56.7 38.7 60.9 62.0 124.1 33.4 56.3 173.9 27.3 67.3 105.7 86.0 14.1 22.0 10.3 21.0 9.3 25.3 15.7 12.8 15.8 33.0 12.0 10.4 4.3 5.8 28.7 32.8 33.6 10.0 3.7 3.8 10.8 5.3 3.2 4.1 4.8 3.8 5.2 3.3 3.7 3.1 6.7 6.4 2.8 5.2 41.2 15.0 4.5 32.8 22.2 13.1 11.2 13.2 10.8 2.8 11.4 1.8 6.2 44.3 30.9 7.5 9.8 4.9 41.3 19.4 16.1 12.7 7.2 122.9 10.3 6.0 38.1 12.1 10.7 10.1 16.5 88.6 17.5 5.5 31.8 1.7 12.4 13.6 20.3 24.5 13.7 51.7 7.5 18.5 0.0 6.5 22.9 12.9 5.2 3.5 2.0 2.6 4.6 17.0 30.8 3.7 6.3 9.4 3.7 6.6 6.6 7.6 12.1 151.7 87.5 41.3 15.3 10.0 27.1 29.6 17.9 3.9 CKAP2L "FLJ40629, radmis" ENSG00000169607 "Cytoskeleton associated protein 2 like" Q8IYA6 2 112736349-112764664 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 13.1;lymphoid tissue: 12.1;testis: 4.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 25.2;Granulosa cells: 12.5;Spermatocytes: 33.0;Spermatogonia: 35.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039407, HPA040057, HPA070737" Uncertain Supported "Microtubules,Mitotic spindle,Cytosol" Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Microtubules, Mitotic spindle" Cytosol "HPA039407: AB_10794091, HPA040057: AB_10794871, HPA070737: AB_2686303" "unprognostic (2.29e-1)" "unprognostic (1.54e-1)" "unprognostic (4.69e-3)" "unprognostic (1.42e-3)" "unprognostic (1.69e-1)" "unprognostic (5.59e-2)" "unprognostic (5.75e-5)" "prognostic unfavorable (7.63e-4)" "unprognostic (2.49e-3)" "unprognostic (1.91e-1)" "unprognostic (9.57e-6)" "unprognostic (2.42e-1)" "unprognostic (0.00e+0)" "unprognostic (7.37e-2)" "unprognostic (1.24e-1)" "unprognostic (1.30e-1)" "unprognostic (4.49e-2)" 0.4 0.1 0.2 2.6 0.2 13.1 0.4 0.4 0.3 0.4 0.0 1.6 1.5 0.3 0.1 2.3 0.1 0.3 0.0 0.2 0.1 0.1 0.3 0.3 5.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.1 2.2 0.2 0.3 0.0 0.0 1.5 1.1 1.1 0.0 0.9 1.0 4.5 0.2 12.1 0.2 0.0 5.2 0.8 0.6 0.2 47.9 9.6 35.4 16.2 2.0 3.3 7.2 38.5 32.2 37.9 36.1 8.7 13.3 32.0 15.5 15.1 48.3 18.0 20.4 19.6 64.1 44.8 8.9 53.6 12.7 7.7 0.1 25.2 30.9 0.9 1.9 47.4 27.2 10.1 17.5 22.8 14.3 44.9 31.2 6.9 31.0 10.6 15.4 20.0 29.5 22.3 37.0 8.4 6.9 18.7 19.7 12.7 15.2 12.8 13.3 13.2 12.4 11.8 12.9 42.7 33.7 34.5 28.5 9.9 20.1 26.6 18.5 18.1 69.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.2 0.2 0.4 0.3 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.1 3.2 0.6 0.0 1.2 3.3 2.1 2.7 0.6 0.0 0.5 0.8 0.5 1.5 0.4 0.0 0.0 11.1 1.3 1.3 0.0 0.4 2.4 1.1 1.6 1.1 0.0 25.2 0.3 0.4 10.6 2.0 1.5 2.1 0.0 12.5 2.9 0.1 6.6 0.0 0.2 3.1 2.0 1.9 1.4 2.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.1 0.0 5.6 1.1 0.1 0.1 0.4 0.0 0.0 0.4 2.8 33.0 35.7 9.5 1.7 1.0 2.5 0.7 3.8 1.1 CLSPN ENSG00000092853 Claspin Q9HAW4 1 35720218-35769978 "Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.3;lymphoid tissue: 7.9;retina: 6.8;testis: 5.7" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 101.0;Spermatocytes: 281.1;Spermatogonia: 263.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Region enriched" "Detected in some" 6 "basal ganglia: 7.8" "Low region specificity" "Detected in many" "HPA026305, HPA026312" Enhanced "Nucleoplasm,Golgi apparatus" Yes Yes "Cluster 17: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Golgi apparatus" "HPA026305: AB_2671833, HPA026312: AB_2671837" "unprognostic (4.75e-2)" "unprognostic (1.01e-1)" "unprognostic (9.64e-3)" "unprognostic (3.54e-2)" "unprognostic (6.82e-2)" "unprognostic (1.62e-2)" "unprognostic (1.18e-6)" "unprognostic (3.99e-3)" "unprognostic (2.08e-3)" "unprognostic (1.63e-2)" "unprognostic (8.71e-6)" "unprognostic (3.23e-2)" "unprognostic (7.61e-6)" "prognostic favorable (4.92e-4)" "unprognostic (5.12e-1)" "unprognostic (1.73e-1)" "unprognostic (1.29e-1)" 0.5 0.2 0.7 3.2 0.6 11.3 0.5 0.6 1.4 0.2 0.4 1.4 1.0 0.4 0.7 0.9 0.2 0.3 0.1 1.3 0.3 0.2 0.5 0.4 4.9 0.4 0.4 0.1 0.1 0.2 0.0 1.5 0.6 0.2 2.0 6.8 0.2 0.1 0.6 1.2 1.0 0.9 0.2 1.3 0.9 5.7 0.6 7.9 0.2 0.0 5.2 0.6 0.4 0.9 22.0 17.5 37.8 19.9 2.6 4.8 14.1 43.6 12.0 31.0 41.3 27.9 19.6 45.7 13.9 11.8 22.7 21.4 37.1 14.9 48.1 31.6 16.8 64.5 38.1 12.6 0.1 54.0 36.8 1.0 0.6 53.8 3.7 3.7 16.9 27.1 44.2 30.8 30.3 14.1 56.9 13.1 36.0 14.9 12.2 36.0 57.0 13.8 6.4 35.3 14.0 16.2 37.7 11.6 7.4 25.6 10.0 21.1 12.5 44.6 33.8 27.6 49.3 11.1 29.1 47.1 14.1 37.4 37.0 1.1 0.3 0.3 0.3 0.2 0.1 0.1 0.2 0.2 0.2 0.3 0.1 0.2 1.0 0.5 0.2 0.2 0.3 0.3 0.7 0.6 0.6 1.4 1.3 0.3 0.4 0.4 0.6 0.2 0.6 0.9 2.6 0.0 0.5 0.3 6.5 5.6 5.7 4.4 1.2 9.4 2.9 3.8 1.4 2.8 2.7 0.0 12.5 19.7 4.6 12.8 0.0 1.6 7.9 1.0 3.6 3.6 1.2 55.6 1.6 0.6 41.1 5.2 4.6 3.3 1.3 12.0 2.2 0.4 16.9 1.7 1.5 9.4 2.0 3.0 8.2 6.1 2.5 5.8 3.6 0.0 9.1 9.4 4.1 0.0 0.6 1.4 9.5 0.4 32.5 1.8 0.4 0.2 0.0 101.0 6.6 5.3 8.7 281.1 263.3 5.8 2.0 10.4 7.2 1.2 12.0 3.9 CLSTN2 "CDHR13, CS2, CSTN2, FLJ39113" ENSG00000158258 "Calsyntenin 2" Q9H4D0 3 139935185-140577397 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 18.2;brain: 26.7;ovary: 64.7" "Cell type enriched" "Detected in many" 4 "Excitatory neurons: 552.2" "Cancer enriched" "Detected in many" 7 "breast cancer: 15.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 32.7;SCLC-21H: 14.5;SuSa: 42.7;THP-1: 9.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031342, HPA061800" Approved Uncertain "Vesicles,Cytokinetic bridge" Yes No 130000 "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "Cytokinetic bridge" "HPA031342: AB_10602800, HPA061800: AB_2684615" "unprognostic (7.58e-2)" "unprognostic (2.64e-2)" "unprognostic (8.02e-2)" "unprognostic (1.51e-3)" "unprognostic (5.52e-3)" "unprognostic (8.35e-2)" "unprognostic (1.58e-1)" "unprognostic (1.21e-1)" "unprognostic (5.58e-1)" "unprognostic (6.25e-2)" "unprognostic (2.24e-1)" "unprognostic (1.81e-1)" "unprognostic (1.71e-1)" "unprognostic (2.52e-2)" "unprognostic (3.16e-2)" "unprognostic (7.63e-5)" "unprognostic (7.22e-5)" 18.2 4.8 17.3 0.3 15.3 0.0 8.8 0.0 26.7 4.2 0.0 1.4 0.5 5.1 0.7 1.0 4.7 2.1 6.1 23.4 0.0 4.3 0.8 1.1 2.7 13.3 3.1 64.7 1.6 0.8 0.9 0.9 9.1 5.3 0.8 2.7 1.3 1.1 1.6 2.0 1.3 6.8 0.0 0.1 1.0 0.6 0.0 0.7 2.8 2.2 0.2 1.6 3.2 15.6 0.0 0.0 5.1 0.0 2.2 0.6 0.0 0.7 0.0 0.0 0.0 2.9 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.1 2.5 0.0 0.1 0.0 32.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 2.1 0.0 0.0 0.0 42.7 2.2 9.4 0.0 1.0 0.5 1.4 0.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 15.3 0.0 26.7 23.4 0.0 13.3 3.1 9.1 0.0 0.0 15.6 2.1 0.0 0.0 18.3 0.0 0.5 0.3 0.0 8.6 1.8 10.9 2.2 8.0 0.0 0.6 3.7 0.0 0.2 0.1 0.0 1.9 0.2 39.8 0.5 8.9 0.8 0.0 0.0 552.2 0.2 0.0 9.1 0.0 0.2 0.0 25.0 2.2 0.0 0.1 0.0 111.5 0.0 0.0 0.3 1.5 31.1 28.0 0.8 0.0 5.6 0.0 0.8 0.0 108.6 29.4 0.0 0.0 0.7 0.0 5.0 0.0 32.3 3.0 3.8 0.0 28.3 13.7 0.8 0.8 0.4 0.0 0.0 0.7 0.5 0.0 0.3 CLTC "CLTCL2, Hc" ENSG00000141367 "Clathrin heavy chain" Q00610 17 59619689-59696956 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, Cell cycle, Cell division, Mitosis" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010389, CAB011571, CAB017155, HPA059143" Approved Enhanced "Vesicles,Endosomes,Lysosomes,Mitotic spindle,Cytosol" Yes No 14000000 "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Vesicles, Endosomes, Lysosomes" "Mitotic spindle, Cytosol" "CAB010389: AB_2083184, CAB011571: AB_2083165, CAB017155: , HPA059143: AB_2683924" "unprognostic (1.56e-1)" "prognostic unfavorable (7.35e-4)" "prognostic favorable (7.65e-4)" "unprognostic (1.03e-1)" "unprognostic (2.62e-1)" "unprognostic (5.23e-3)" "prognostic unfavorable (5.54e-4)" "unprognostic (1.11e-1)" "unprognostic (6.43e-2)" "unprognostic (1.09e-1)" "unprognostic (3.34e-2)" "unprognostic (2.69e-1)" "unprognostic (1.49e-1)" "unprognostic (1.18e-1)" "unprognostic (9.22e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.02e-4)" 105.4 95.2 42.1 89.7 54.9 96.3 81.6 67.3 103.9 92.3 36.7 121.7 74.1 83.1 126.4 82.1 67.8 88.9 90.7 60.7 65.1 125.5 117.7 82.1 75.5 95.5 52.4 73.2 56.8 186.8 51.6 139.6 95.2 97.8 128.3 163.6 68.6 104.2 88.4 81.3 73.3 121.0 43.8 78.8 91.2 71.3 68.2 76.0 114.1 83.9 86.8 101.1 51.6 55.0 293.3 426.1 207.6 207.0 345.8 280.5 240.0 305.7 321.7 268.2 278.9 264.7 175.2 200.6 340.1 436.4 296.9 186.2 313.6 255.1 356.2 214.4 166.8 328.2 248.8 414.0 262.3 228.5 182.3 266.9 154.6 408.0 262.3 211.4 302.0 99.9 334.4 280.4 429.1 511.1 135.6 65.1 179.6 263.3 248.2 118.7 343.6 244.9 297.5 404.1 184.1 216.7 188.3 122.9 180.4 270.5 290.3 142.3 385.6 492.4 287.9 237.0 317.8 213.3 320.3 181.4 357.7 151.6 305.3 16.6 33.1 21.3 17.5 36.3 21.7 13.7 16.1 19.2 36.5 12.9 13.4 15.0 19.9 18.9 32.5 22.8 22.1 23.3 42.1 54.9 67.3 103.9 60.7 65.1 95.5 52.4 95.2 43.8 68.2 55.0 62.6 99.3 107.9 80.3 46.3 63.9 44.4 75.6 28.5 91.9 58.5 34.7 77.9 71.4 103.3 77.3 60.5 109.1 60.7 184.0 27.4 76.2 23.3 95.5 95.6 79.7 120.6 115.9 137.7 97.7 47.7 84.5 99.4 106.1 68.4 75.5 120.7 185.4 182.5 85.8 135.9 120.7 77.3 195.0 93.2 77.2 74.0 128.3 53.4 79.6 102.8 53.9 38.1 73.4 124.2 106.2 76.1 93.6 83.0 86.3 102.7 132.4 128.0 65.2 78.9 66.0 82.8 52.7 38.0 60.5 79.3 107.9 45.9 81.3 127.8 91.6 CNFN PLAC8L2 ENSG00000105427 Cornifelin Q9BYD5 19 42387019-42390297 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 952.0;esophagus: 3093.3;vagina: 1442.7" "Cell type enhanced" "Detected in many" "Breast glandular cells: 57.9;Breast myoepithelial cells: 51.6;Squamous epithelial cells: 71.8" "Cancer enhanced" "Detected in all" "head and neck cancer: 367.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "memory B-cell: 61.2;naive B-cell: 70.2" "Lineage enriched" "Detected in many" 12 "B-cells: 70.2" "Cell line enhanced" "Detected in many" "A549: 18.1;HEK 293: 25.7;MCF7: 12.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA049073, HPA053997" Enhanced Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Microtubules "Cytokinetic bridge" "HPA049073: AB_2680620, HPA053997: AB_2682337" "unprognostic (5.08e-2)" "unprognostic (4.21e-3)" "unprognostic (2.52e-1)" "unprognostic (7.22e-2)" "unprognostic (3.15e-2)" "unprognostic (8.35e-3)" "unprognostic (6.04e-2)" "unprognostic (2.06e-3)" "unprognostic (3.52e-1)" "unprognostic (9.44e-2)" "unprognostic (1.39e-1)" "unprognostic (8.37e-2)" "unprognostic (8.42e-2)" "unprognostic (4.83e-2)" "unprognostic (7.77e-3)" "prognostic favorable (4.02e-5)" "unprognostic (2.45e-1)" 4.3 5.3 1.8 0.4 4.2 0.6 12.9 1.9 2.2 952.0 1.3 3.2 0.4 1.5 7.3 3093.3 1.6 0.1 1.9 1.9 2.8 2.3 1.4 0.9 0.7 2.1 1.9 1.0 3.3 1.6 2.2 0.1 1.7 8.6 1.3 0.1 661.6 1.1 1.7 555.6 3.5 0.5 1.7 3.3 3.3 2.4 2.9 2.8 1.8 0.0 276.8 2.4 1442.7 1.6 6.0 18.1 0.4 1.6 0.8 0.9 0.2 1.0 0.3 0.4 0.4 1.0 1.6 5.1 8.0 0.2 1.2 2.4 1.5 2.3 0.1 0.0 25.7 0.4 6.9 1.9 0.0 0.0 0.1 1.8 4.0 1.0 0.0 0.1 0.0 4.7 1.1 0.2 0.0 12.6 0.1 0.1 6.6 8.1 5.4 2.2 0.3 2.9 1.6 2.3 2.7 7.7 3.4 5.1 2.5 2.7 6.2 2.6 0.0 0.0 5.3 0.2 0.1 5.8 7.6 3.6 0.1 2.2 0.3 0.1 4.6 0.1 1.7 3.9 0.4 61.2 1.3 1.2 5.9 70.2 0.6 0.9 1.3 0.0 0.9 1.3 0.1 2.2 1.8 4.2 1.9 2.2 1.9 2.8 2.1 1.9 1.7 1.7 2.9 1.6 32.7 3.2 2.2 0.0 24.6 4.6 16.8 28.5 14.8 0.1 57.9 51.6 0.8 2.8 20.2 33.1 0.0 0.2 2.1 24.5 7.9 13.1 1.5 20.6 3.9 9.3 32.5 3.6 0.1 2.5 0.3 2.3 4.6 23.9 4.5 7.2 3.9 0.7 5.7 0.0 0.2 33.4 14.2 3.8 7.7 3.9 5.3 6.3 3.6 0.0 6.4 0.3 7.2 0.0 0.1 2.4 39.4 4.5 0.5 11.5 43.8 12.3 10.5 0.1 0.0 0.9 8.0 0.4 17.4 71.8 12.9 0.3 1.3 1.1 41.8 27.0 COPS2 "ALIEN, CSN2, TRIP15" ENSG00000166200 "COP9 signalosome subunit 2" P61201 15 49106068-49155661 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016867, HPA018271, HPA061071" Approved Supported "Vesicles,Cytokinetic bridge" Yes No 190000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" Vesicles "Cytokinetic bridge" "HPA016867: AB_1858336, HPA018271: AB_1858335, HPA061071: AB_2684424" "unprognostic (3.47e-1)" "unprognostic (2.28e-2)" "unprognostic (1.66e-1)" "unprognostic (7.20e-2)" "unprognostic (1.86e-1)" "unprognostic (7.84e-3)" "unprognostic (1.04e-1)" "unprognostic (6.77e-2)" "unprognostic (2.49e-2)" "unprognostic (6.09e-2)" "unprognostic (3.86e-3)" "unprognostic (1.42e-1)" "unprognostic (4.35e-3)" "unprognostic (1.02e-1)" "unprognostic (1.97e-1)" "unprognostic (5.62e-2)" "unprognostic (1.10e-3)" 61.7 43.4 24.8 34.4 28.5 124.5 67.0 35.0 36.8 61.9 25.3 43.2 43.3 58.4 44.0 63.2 43.2 53.7 61.5 26.1 30.4 60.8 57.6 35.0 45.5 30.9 27.7 76.7 54.0 65.7 26.4 45.0 32.8 45.2 41.6 32.2 40.0 47.0 92.6 35.5 37.2 56.5 35.2 32.0 36.4 51.0 27.5 49.6 61.8 112.1 48.8 59.0 35.3 41.7 92.0 53.1 111.6 94.4 134.2 189.9 76.7 157.3 149.8 135.4 123.5 113.0 49.1 151.1 105.2 152.2 108.7 131.9 160.3 130.9 148.0 103.3 64.5 141.0 105.4 91.7 102.6 134.7 70.7 161.2 104.3 110.4 193.3 149.3 144.0 82.5 184.4 78.8 149.3 49.5 72.3 67.3 72.6 128.4 68.9 78.2 105.2 227.7 143.5 136.5 108.4 78.6 90.7 96.4 127.8 129.4 95.6 133.3 93.4 132.1 71.0 249.6 167.9 71.0 196.3 191.0 123.4 215.1 109.4 11.7 17.9 12.2 13.1 23.5 24.4 14.6 19.7 19.2 21.0 13.9 24.8 16.2 7.4 16.6 22.9 13.3 28.4 16.0 24.8 28.5 35.0 36.8 26.1 30.4 30.9 27.7 32.8 35.2 27.5 41.7 72.8 76.9 56.1 14.4 50.0 87.1 57.1 90.8 80.8 23.2 47.6 59.3 104.3 27.1 69.8 23.9 10.4 56.1 48.2 18.5 54.8 40.3 28.2 56.7 91.6 53.6 20.8 50.1 35.2 29.9 71.0 79.6 36.2 94.0 52.6 39.3 46.1 32.5 43.9 33.7 36.1 25.1 32.6 47.5 44.9 21.6 55.3 46.1 35.6 19.7 49.3 24.8 27.8 21.6 48.7 35.9 21.6 53.4 63.5 53.0 41.0 84.8 47.4 19.7 19.7 74.6 109.0 93.1 43.3 63.2 98.9 131.9 54.0 58.6 34.6 64.4 CORIN "ATC2, CRN, Lrp4, PRSC, TMPRSS10" ENSG00000145244 "Corin, serine peptidase" Q9Y5Q5 4 47593999-47838106 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "heart muscle: 56.9" "Cell type enriched" "Detected in some" 6 "Cardiomyocytes: 69.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "ASC TERT1: 44.0" "Region enhanced" "Detected in some" "basal ganglia: 2.6" "Low region specificity" "Detected in some" HPA070941 Approved "Nuclear bodies,Plasma membrane,Actin filaments" "Intracellular and membrane" Yes No "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Nuclear bodies, Actin filaments" "HPA070941: AB_2686324" "unprognostic (1.05e-1)" "unprognostic (2.52e-1)" "unprognostic (1.14e-1)" "unprognostic (1.93e-1)" "unprognostic (2.10e-1)" "unprognostic (3.18e-1)" "unprognostic (3.58e-4)" "unprognostic (3.19e-1)" "unprognostic (3.67e-2)" "unprognostic (8.22e-2)" "unprognostic (9.78e-2)" "unprognostic (6.53e-2)" "unprognostic (1.18e-1)" "unprognostic (2.86e-2)" "unprognostic (5.18e-2)" "unprognostic (7.22e-2)" "unprognostic (1.33e-2)" 0.4 0.1 0.1 0.1 0.1 0.0 1.0 0.1 0.2 2.1 0.6 0.3 0.1 4.5 0.6 0.9 1.4 4.5 56.9 0.0 0.3 1.0 0.1 1.9 0.0 0.7 0.6 0.5 0.2 1.1 1.9 0.4 0.1 2.3 0.0 0.3 0.4 6.1 0.1 7.5 0.3 0.7 0.1 1.1 0.5 2.5 0.3 0.1 0.1 0.1 0.1 1.2 3.9 0.1 0.0 0.0 0.1 0.3 10.3 44.0 0.0 2.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 2.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.9 1.4 0.0 0.3 0.2 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.3 0.7 0.6 0.1 0.1 0.3 0.1 0.3 0.0 7.5 1.0 0.0 3.8 0.3 0.0 0.0 1.0 8.3 0.3 69.4 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.1 1.3 1.0 0.0 0.0 6.5 0.0 0.0 9.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 10.8 0.0 0.0 0.6 5.5 2.0 4.7 0.1 5.4 1.0 0.0 0.7 0.0 2.0 3.9 0.0 0.0 2.6 0.0 0.6 0.0 0.2 0.0 0.3 0.0 0.3 2.3 4.6 4.4 0.1 2.7 0.0 0.6 0.1 0.0 0.3 CPEB2 ENSG00000137449 "Cytoplasmic polyadenylation element binding protein 2" Q7Z5Q1 4 15002481-15070153 "Predicted intracellular proteins" "Translation regulation" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 127.6;Oligodendrocytes: 406.5;Suprabasal keratinocytes: 129.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 57.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072513 Approved Cytosol Yes No "Cluster 40: NK-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA072513: AB_2686529" "unprognostic (6.59e-2)" "unprognostic (4.21e-3)" "unprognostic (4.75e-2)" "unprognostic (2.60e-1)" "unprognostic (1.06e-1)" "unprognostic (1.80e-2)" "unprognostic (2.36e-2)" "unprognostic (5.67e-3)" "unprognostic (1.33e-1)" "unprognostic (1.65e-1)" "unprognostic (4.58e-2)" "unprognostic (2.06e-1)" "unprognostic (8.62e-2)" "unprognostic (1.09e-1)" "unprognostic (1.28e-1)" "unprognostic (1.81e-1)" "unprognostic (8.34e-2)" 9.6 6.0 13.2 5.1 21.9 26.5 12.3 18.8 21.9 9.8 5.6 11.5 8.4 7.4 8.3 13.3 6.0 9.5 7.3 14.6 15.0 12.0 17.6 8.4 5.6 22.4 16.6 6.3 4.4 16.3 4.2 6.4 20.7 8.4 9.7 16.1 8.1 10.7 5.8 23.5 8.7 8.6 18.7 5.8 10.7 37.9 17.3 4.5 4.8 6.2 6.4 8.0 13.2 45.5 2.9 18.1 1.9 0.7 13.1 26.2 3.6 10.8 6.7 5.8 4.6 0.3 4.2 1.9 2.1 10.1 11.8 3.5 3.9 2.6 3.6 4.8 1.5 0.5 16.3 3.5 6.1 1.0 2.6 12.3 12.5 15.6 14.7 8.7 6.1 0.3 0.4 13.2 26.9 1.5 0.2 4.7 1.7 5.9 2.8 0.3 1.8 0.8 57.3 2.6 1.7 11.1 3.1 2.4 10.6 8.7 1.5 12.2 11.7 24.0 2.1 15.3 6.1 9.0 1.3 1.0 19.3 10.6 9.5 0.0 0.2 0.6 0.1 0.1 0.5 0.0 0.2 0.1 0.2 0.1 0.3 0.1 1.1 0.5 0.1 0.1 0.1 0.1 13.2 21.9 18.8 21.9 14.6 15.0 22.4 16.6 20.7 18.7 17.3 45.5 24.9 32.1 14.2 55.8 8.1 85.8 12.2 6.8 58.1 8.6 31.2 17.8 22.3 12.8 9.3 31.3 27.1 1.4 10.7 26.4 1.9 4.6 64.5 38.4 9.9 14.7 10.2 3.8 58.2 4.9 1.8 13.4 15.3 50.7 10.8 1.8 13.2 23.8 11.2 15.2 127.6 13.1 4.1 14.1 31.0 20.3 6.2 20.3 53.4 39.4 6.6 8.5 3.1 89.5 406.5 7.0 16.9 8.2 17.5 11.8 18.7 14.8 5.1 19.3 0.0 20.7 16.5 16.6 4.6 77.0 129.4 1.4 11.0 3.6 8.1 17.0 CPEB3 KIAA0940 ENSG00000107864 "Cytoplasmic polyadenylation element binding protein 3" Q8NE35 10 92046692-92291078 "Predicted intracellular proteins" "Translation regulation" "Activator, Repressor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 32.2" "Cell type enhanced" "Detected in many" "Astrocytes: 176.0;Early spermatids: 226.2;Excitatory neurons: 233.7;Inhibitory neurons: 286.9;Late spermatids: 408.9;Oligodendrocyte precursor cells: 148.8;Oligodendrocytes: 128.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Karpas-707: 12.1;U-266/70: 6.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070942 Approved "Nucleoplasm,Plasma membrane,Midbody,Cytosol" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nucleoplasm, Plasma membrane, Midbody" "HPA070942: " "unprognostic (4.90e-2)" "unprognostic (2.12e-2)" "unprognostic (3.00e-1)" "unprognostic (5.66e-2)" "unprognostic (1.92e-1)" "unprognostic (2.95e-5)" "prognostic favorable (5.06e-5)" "unprognostic (4.09e-4)" "unprognostic (2.73e-1)" "unprognostic (2.40e-1)" "unprognostic (1.47e-2)" "unprognostic (2.42e-2)" "prognostic favorable (3.84e-9)" "unprognostic (3.33e-2)" "unprognostic (7.42e-2)" "unprognostic (1.36e-2)" "unprognostic (1.40e-1)" 1.9 3.9 6.1 1.8 7.2 1.7 3.2 6.2 17.3 2.5 2.1 2.3 3.1 1.9 4.5 4.6 1.8 2.0 5.1 6.4 4.3 4.6 32.2 2.2 1.9 10.4 5.6 3.5 3.5 3.2 4.0 1.6 11.0 4.2 2.6 7.1 7.5 2.4 19.7 4.0 3.0 2.0 1.4 2.6 2.8 12.9 4.4 1.5 6.5 9.5 2.1 1.9 3.1 7.0 0.9 0.2 0.3 1.9 0.5 0.5 0.7 0.8 0.6 1.2 0.9 0.6 1.9 1.1 1.0 0.3 0.5 2.5 0.9 0.6 0.7 1.1 0.9 1.4 1.3 0.8 1.4 0.6 1.4 0.4 1.5 0.6 2.4 1.0 1.1 1.3 0.9 12.1 0.5 0.7 0.9 0.8 0.2 1.3 0.9 1.1 1.6 2.1 1.2 0.4 1.4 0.5 0.8 2.2 1.6 1.0 2.7 1.6 0.8 0.6 0.6 0.4 0.7 6.3 1.7 1.1 0.3 2.2 0.1 2.6 0.4 0.8 0.2 0.5 0.2 0.7 0.1 0.3 0.3 0.1 0.1 0.1 0.5 0.2 0.6 0.2 0.1 0.2 6.1 7.2 6.2 17.3 6.4 4.3 10.4 5.6 11.0 1.4 4.4 7.0 6.1 6.4 7.0 176.0 6.2 8.8 4.0 4.0 7.4 26.0 20.5 10.7 25.3 5.7 4.4 12.9 50.1 2.1 3.0 11.3 5.9 3.2 226.2 9.0 3.0 7.1 19.8 3.6 233.7 2.6 1.6 5.5 4.1 10.8 3.8 4.1 12.5 75.2 4.8 30.3 286.9 9.9 8.2 23.9 3.4 408.9 5.9 10.3 5.4 87.1 8.9 3.2 4.1 148.8 128.6 3.2 4.0 7.9 4.2 10.7 10.1 5.0 8.7 24.7 0.0 4.4 4.1 13.2 7.2 22.0 13.9 1.2 3.3 3.4 5.9 6.5 CPT2 "CPT1, CPTASE" ENSG00000157184 "Carnitine palmitoyltransferase 2" P23786 1 53196792-53214197 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 91.2" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 85.1;Hepatocytes: 88.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028201, HPA028202, HPA028214" Enhanced Approved Nucleoplasm,Nucleoli,Mitochondria Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Mitochondria" Nucleoli "HPA028201: AB_10599177, HPA028202: AB_10599942, HPA028214: AB_10601958" "unprognostic (2.43e-1)" "unprognostic (2.27e-1)" "prognostic favorable (5.27e-4)" "unprognostic (6.48e-2)" "unprognostic (1.88e-1)" "unprognostic (9.34e-2)" "unprognostic (6.48e-2)" "unprognostic (1.75e-2)" "unprognostic (2.86e-1)" "unprognostic (1.67e-1)" "unprognostic (3.00e-2)" "unprognostic (8.97e-2)" "prognostic favorable (1.46e-12)" "unprognostic (4.00e-2)" "unprognostic (2.06e-1)" "unprognostic (1.79e-2)" "unprognostic (2.95e-2)" 12.9 14.3 6.6 9.4 8.2 5.4 13.6 7.9 7.3 10.3 16.8 35.4 32.4 6.8 10.5 14.2 10.5 9.5 19.5 6.1 7.1 35.1 91.2 11.5 10.6 8.1 7.5 10.2 21.7 27.3 6.7 18.0 8.0 12.2 32.8 7.1 14.6 11.7 17.3 6.7 24.9 11.4 7.7 8.7 18.4 12.9 9.0 10.2 12.5 33.1 13.2 11.1 4.5 8.9 16.0 8.3 17.2 17.8 14.6 11.3 17.5 9.8 13.2 17.5 17.5 8.6 14.5 28.9 14.6 9.2 20.1 19.1 35.1 25.1 15.1 17.0 16.0 21.8 9.9 6.4 25.9 15.9 19.5 23.0 23.2 13.8 11.1 18.6 15.4 26.5 20.9 9.9 13.1 12.8 10.7 13.0 29.8 38.4 20.0 13.2 16.2 34.4 22.9 22.0 25.3 14.4 22.1 30.3 39.7 36.6 32.3 32.2 8.7 8.4 6.1 16.5 8.5 26.3 19.8 16.2 11.6 20.6 12.4 5.6 14.1 14.6 7.2 20.0 8.1 5.3 6.3 8.4 17.9 7.4 10.5 7.2 5.3 6.9 20.5 8.9 9.9 10.3 6.6 8.2 7.9 7.3 6.1 7.1 8.1 7.5 8.0 7.7 9.0 8.9 5.0 12.8 24.1 4.2 7.8 1.8 5.2 20.5 5.2 6.0 7.5 7.0 18.1 15.7 11.4 11.0 14.6 85.1 4.5 49.3 25.4 12.9 1.1 10.9 8.1 5.9 14.5 9.4 1.5 10.5 20.3 7.2 18.3 10.3 2.5 12.7 8.9 88.8 26.3 15.2 2.0 26.6 16.2 15.1 7.2 2.8 6.8 10.5 7.2 1.9 20.2 11.6 6.2 2.5 4.5 10.5 25.6 5.3 9.1 4.9 38.6 41.0 7.6 11.0 6.6 7.5 8.4 49.9 31.3 13.8 2.6 54.6 6.9 25.6 29.5 5.7 CRACDL "C2orf55, KIAA1211L, MGC42367" ENSG00000196872 "CRACD like" Q6NV74 2 98793846-98936259 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.8;epididymis: 31.6" "Cell type enriched" "Detected in some" 9 "Adipocytes: 35.9" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 6 "amygdala: 12.8;basal ganglia: 20.0;cerebral cortex: 30.8;hippocampal formation: 29.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 41.0;HDLM-2: 61.7;Karpas-707: 17.4;MCF7: 16.3;SiHa: 17.3;SK-BR-3: 22.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "amygdala: 19.1;basal ganglia: 45.5;cerebral cortex: 36.9;hippocampal formation: 54.9;olfactory bulb: 15.9" "HPA051082, HPA061678" Enhanced Approved "Microtubules,Cytokinetic bridge,Centrosome" Yes No "Cluster 68: Epididymis - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Microtubules, Centrosome" "Cytokinetic bridge" "HPA051082: AB_2681337, HPA061678: AB_2684584" "unprognostic (3.56e-3)" "unprognostic (1.23e-3)" "unprognostic (5.88e-2)" "unprognostic (6.43e-2)" "unprognostic (1.34e-1)" "unprognostic (1.24e-1)" "unprognostic (3.67e-3)" "unprognostic (2.12e-1)" "unprognostic (5.10e-2)" "unprognostic (7.65e-2)" "unprognostic (3.23e-2)" "unprognostic (3.61e-2)" "prognostic favorable (1.13e-5)" "unprognostic (1.22e-1)" "unprognostic (3.34e-1)" "prognostic favorable (1.33e-5)" "unprognostic (2.22e-2)" 5.0 0.9 12.8 1.5 20.0 0.5 5.1 0.0 30.8 5.1 0.0 5.9 8.0 2.1 31.6 11.2 22.6 2.9 3.4 29.7 0.0 4.1 0.3 6.0 0.8 0.0 0.0 0.6 4.7 7.7 6.6 4.5 0.0 2.3 4.6 0.1 11.0 4.6 1.7 6.4 7.5 2.3 0.0 1.3 8.3 6.2 0.0 1.0 5.0 1.5 1.8 2.2 5.5 3.6 8.4 0.4 0.2 3.2 0.0 0.0 41.0 0.0 0.0 0.0 0.0 0.4 4.9 0.0 10.4 0.0 0.2 7.4 0.3 0.4 0.0 61.7 1.2 0.0 0.5 0.5 0.0 0.0 0.1 0.3 2.3 0.1 1.2 0.1 2.5 0.0 0.0 17.4 0.0 16.3 0.2 1.3 0.1 8.3 0.9 0.0 0.0 0.8 3.2 6.5 5.8 0.9 17.3 22.5 0.1 0.0 8.7 1.4 10.7 0.0 1.3 0.0 0.1 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.8 20.0 0.0 30.8 29.7 0.0 0.0 0.0 0.0 0.0 0.0 3.6 35.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 CRYBB3 CRYB3 ENSG00000100053 "Crystallin beta B3" P26998 22 25199858-25207359 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Distal enterocytes: 2.6;Distal tubular cells: 1.9;granulocytes: 4.5;Muller glia cells: 4.3;Proximal tubular cells: 10.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.4;HEK 293: 1.4;HeLa: 1.8;hTERT-HME1: 1.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA055840 Supported Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA055840: AB_2682939" "unprognostic (1.36e-2)" "unprognostic (6.27e-4)" "unprognostic (6.30e-3)" "unprognostic (5.34e-2)" "unprognostic (8.76e-2)" "unprognostic (3.15e-2)" "unprognostic (6.45e-2)" "unprognostic (2.07e-2)" "unprognostic (4.15e-2)" "unprognostic (8.28e-2)" "unprognostic (2.40e-1)" "unprognostic (2.68e-2)" "unprognostic (1.03e-2)" "unprognostic (2.01e-1)" "unprognostic (1.76e-1)" "unprognostic (1.91e-1)" "unprognostic (1.20e-3)" 0.2 0.5 0.9 0.1 0.6 0.0 0.7 0.0 1.0 0.5 0.0 0.6 0.3 0.3 0.2 0.6 0.4 0.4 0.5 0.9 0.0 2.0 2.0 0.3 0.1 0.0 0.1 0.1 0.3 0.0 0.3 0.1 0.0 0.8 0.4 0.7 1.0 0.4 0.7 0.9 0.7 0.1 0.0 0.1 0.5 0.2 0.5 0.2 1.3 0.1 0.3 0.1 0.4 0.0 0.6 0.2 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.3 0.0 0.2 1.4 0.8 0.6 0.0 0.0 1.4 0.0 1.8 1.0 0.0 0.0 0.0 0.0 0.7 0.4 1.2 0.2 0.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 1.1 0.0 0.1 0.0 0.1 0.2 0.2 0.1 0.1 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.6 0.5 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.6 0.0 1.0 0.9 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.6 0.3 0.4 1.5 0.1 0.0 0.0 0.0 0.0 2.6 1.9 0.0 0.2 0.1 0.1 0.3 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.5 4.5 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 1.3 10.5 0.4 0.3 0.0 0.0 0.1 0.1 0.7 0.0 0.3 0.0 0.1 0.0 0.3 0.1 CTTNBP2 "C7orf8, CORTBP2, KIAA1758, Orf4" ENSG00000077063 "Cortactin binding protein 2" Q8WZ74 7 117710651-117874139 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 128.8;granulocytes: 139.9;Inhibitory neurons: 194.9;Oligodendrocyte precursor cells: 428.8;Oligodendrocytes: 444.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "non-classical monocyte: 7.7" "Lineage enriched" "Detected in single" 26 "monocytes: 7.7" "Group enriched" "Detected in some" 6 "HEL: 57.6;HMC-1: 74.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009151, HPA044654" Enhanced Approved "Midbody ring,Cytosol" Yes No "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Midbody ring, Cytosol" "CAB009151: AB_2088281, HPA044654: AB_2679037" "unprognostic (6.28e-2)" "unprognostic (2.90e-1)" "unprognostic (5.11e-2)" "unprognostic (1.81e-3)" "unprognostic (1.21e-1)" "unprognostic (3.64e-1)" "unprognostic (7.38e-2)" "unprognostic (3.28e-4)" "unprognostic (3.83e-1)" "unprognostic (7.98e-2)" "unprognostic (7.93e-3)" "unprognostic (1.20e-1)" "prognostic favorable (3.71e-5)" "unprognostic (1.10e-1)" "unprognostic (1.27e-1)" "unprognostic (6.06e-2)" "unprognostic (2.45e-3)" 6.9 1.8 11.4 0.7 16.7 0.0 3.8 13.0 14.7 5.7 6.8 2.4 1.6 10.6 4.8 12.1 6.0 3.5 1.8 12.7 14.8 6.4 1.8 1.8 0.2 15.7 14.7 3.1 7.8 9.3 2.9 1.7 16.3 3.4 2.4 7.9 3.4 1.8 0.5 1.8 2.4 5.2 11.9 2.2 1.3 1.0 15.1 0.7 5.5 0.9 0.9 4.2 4.2 26.1 0.0 0.9 1.6 0.0 0.0 0.0 1.2 0.2 0.6 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.1 8.3 0.0 0.0 0.0 2.5 57.6 0.5 0.0 0.2 0.0 74.1 0.3 0.4 0.0 0.0 1.0 1.6 0.0 0.0 0.1 1.1 0.0 0.0 0.0 10.6 0.0 0.3 0.0 0.0 0.2 10.6 0.0 6.1 0.0 0.0 0.0 0.2 4.6 0.0 0.0 0.0 2.6 1.0 0.1 0.0 0.7 0.0 0.2 5.0 0.0 1.3 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 11.4 16.7 13.0 14.7 12.7 14.8 15.7 14.7 16.3 11.9 15.1 26.1 15.6 3.2 4.8 10.1 0.0 1.9 3.4 3.7 15.9 33.6 1.9 6.7 3.6 10.0 5.6 7.3 56.3 2.8 0.3 1.8 1.9 6.3 1.8 5.1 32.5 10.2 1.8 0.0 128.8 4.2 2.1 9.1 1.1 7.4 139.9 3.8 20.0 1.1 9.2 74.0 194.9 1.1 24.4 10.1 12.3 3.3 0.9 8.0 7.2 75.9 1.3 97.2 0.0 428.8 444.2 0.6 2.1 1.2 0.3 2.1 0.3 24.3 1.4 6.6 0.0 3.3 9.6 0.6 2.1 38.8 0.3 1.1 2.7 0.2 6.8 1.4 CXCR2 "CD182, CMKAR2, IL8RB" ENSG00000180871 "C-X-C motif chemokine receptor 2" P25025 2 218125289-218137251 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 27.2;lymphoid tissue: 40.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 10.5;dendritic cells: 12.9;granulocytes: 6.3;NK-cells: 40.2;Squamous epithelial cells: 11.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 52 "neutrophil: 3273.9" "Lineage enriched" "Detected in many" 111 "granulocytes: 3273.9" "Group enriched" "Detected in some" 11 "BEWO: 14.5;HL-60: 8.2;HMC-1: 16.5;THP-1: 15.3;U-937: 15.1" "Low region specificity" "Detected in all" "CAB016268, HPA031999, HPA032017" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Mitotic spindle" Yes NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Nucleoplasm, Microtubules, Mitotic spindle" "CAB016268: AB_626893, HPA031999: AB_2674105, HPA032017: AB_2674112" "unprognostic (4.89e-2)" "unprognostic (2.01e-1)" "unprognostic (5.63e-2)" "unprognostic (1.10e-2)" "unprognostic (1.58e-1)" "unprognostic (3.13e-1)" "unprognostic (1.33e-1)" "unprognostic (2.13e-1)" "unprognostic (5.96e-2)" "unprognostic (1.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-1)" "unprognostic (7.54e-2)" "unprognostic (1.04e-1)" "unprognostic (7.23e-2)" "unprognostic (8.18e-2)" "unprognostic (5.48e-2)" 13.8 1.5 0.3 40.0 0.6 7.3 0.8 0.2 2.6 4.5 0.1 0.9 0.2 0.4 1.3 27.2 2.9 7.8 1.0 0.3 0.1 0.4 2.4 6.5 0.7 0.6 0.5 0.4 2.9 0.4 0.2 4.6 1.4 0.6 0.7 0.0 3.0 3.8 0.5 4.8 1.2 2.4 0.3 27.3 0.7 0.2 0.5 2.8 0.6 11.6 3.0 7.8 7.3 0.4 0.0 0.0 0.1 0.0 0.0 0.0 14.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.2 16.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 1.3 0.2 0.0 0.0 0.4 0.0 1.3 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.5 0.0 15.3 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 15.1 0.0 63.5 29.5 50.3 28.8 7.4 0.4 0.2 1.3 7.3 13.5 0.2 1.1 9.9 3273.9 6.8 3.6 25.0 0.5 17.4 0.3 0.6 0.2 2.6 0.3 0.1 0.6 0.5 1.4 0.3 0.5 0.4 0.0 0.0 10.5 0.0 0.1 0.0 0.9 0.2 0.0 0.0 0.0 0.4 0.2 0.0 1.9 0.0 0.0 0.7 12.9 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.5 1.2 0.0 0.0 6.3 3.3 0.0 0.0 1.6 0.0 0.0 0.0 0.0 2.2 1.6 0.0 0.0 2.8 0.0 1.0 3.7 0.0 40.2 0.0 0.1 0.0 2.2 0.0 1.4 0.1 0.0 0.1 0.3 0.0 0.0 0.4 0.4 0.0 0.0 11.6 0.1 0.3 4.1 0.1 0.1 1.9 CYLD "CYLD1, KIAA0849, USPL2" ENSG00000083799 "CYLD lysine 63 deubiquitinase" Q9NQC7 16 50742050-50801935 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Immunity, Innate immunity, Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 94.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 136.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011713, HPA050095" Approved Supported "Nucleoplasm,Centriolar satellite" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Centriolar satellite" Nucleoplasm "CAB011713: AB_731794, HPA050095: AB_2681013" "unprognostic (9.83e-2)" "unprognostic (1.17e-2)" "unprognostic (5.01e-2)" "unprognostic (2.83e-2)" "unprognostic (3.84e-1)" "unprognostic (5.06e-2)" "unprognostic (3.87e-2)" "unprognostic (3.24e-2)" "unprognostic (9.46e-2)" "unprognostic (1.11e-1)" "unprognostic (1.18e-2)" "unprognostic (2.32e-1)" "unprognostic (1.03e-1)" "unprognostic (1.07e-1)" "unprognostic (3.43e-2)" "unprognostic (6.83e-2)" "unprognostic (8.42e-2)" 14.3 22.0 23.9 38.8 23.5 94.3 13.6 17.9 18.2 13.0 22.3 16.3 16.1 15.1 12.1 23.3 11.0 20.5 20.1 17.3 23.3 14.2 21.0 21.5 53.4 21.3 27.8 15.4 15.2 23.0 15.4 15.4 23.6 16.3 19.3 22.0 18.9 16.0 34.3 15.2 16.2 16.8 21.6 39.0 19.9 38.3 32.7 35.6 24.9 20.5 48.4 24.1 12.9 24.2 26.9 8.3 9.4 10.6 14.3 21.0 8.7 39.1 56.7 39.9 23.4 6.9 12.5 30.7 13.7 38.3 43.4 10.3 11.3 23.7 58.7 136.6 16.6 15.5 15.3 5.8 29.1 15.4 69.5 23.0 18.6 48.1 50.1 37.7 16.3 21.3 6.6 26.1 56.4 4.0 14.4 22.3 10.1 8.5 13.3 13.4 18.8 29.4 12.9 9.1 12.0 9.2 33.1 11.2 9.8 14.3 11.0 18.9 18.6 67.2 15.4 23.4 15.9 68.0 68.4 33.2 49.3 16.7 14.7 64.6 15.2 38.3 18.1 17.7 21.8 17.2 27.1 24.5 18.3 11.1 24.4 19.4 32.3 25.7 18.8 11.0 37.3 19.5 23.9 23.5 17.9 18.2 17.3 23.3 21.3 27.8 23.6 21.6 32.7 24.2 28.8 44.8 31.8 31.6 87.7 120.1 59.5 32.2 40.9 89.2 35.5 26.0 34.4 21.5 32.9 18.4 93.8 6.8 84.1 28.3 5.9 20.0 48.2 22.5 24.9 36.0 31.1 26.1 51.9 19.1 4.4 37.3 22.4 47.1 80.5 21.4 27.8 25.5 21.5 67.3 54.7 10.7 30.5 40.0 127.6 31.3 25.4 66.4 74.7 57.1 63.7 23.3 70.0 51.8 119.2 18.0 22.4 21.1 79.7 66.4 15.4 13.9 23.3 48.3 6.6 54.2 30.5 59.2 15.2 64.3 155.6 4.1 119.5 21.3 14.8 66.7 CYSRT1 "C9orf169, MGC59937" ENSG00000197191 "Cysteine rich tail 1" A8MQ03 9 137224635-137226315 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 239.5" "Group enriched" "Detected in some" 10 "Pancreatic endocrine cells: 58.0;Squamous epithelial cells: 66.0" "Cancer enhanced" "Detected in all" "head and neck cancer: 23.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 25.1;CAPAN-2: 28.9;HaCaT: 33.3;HeLa: 30.6;MCF7: 49.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021883, HPA021886" Approved Approved "Nuclear speckles,Vesicles,Midbody" Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear speckles" "Vesicles, Midbody" "HPA021883: AB_1853190, HPA021886: AB_1853192" "unprognostic (1.35e-1)" "unprognostic (2.53e-2)" "unprognostic (8.31e-3)" "unprognostic (6.87e-3)" "unprognostic (2.14e-1)" "unprognostic (2.66e-2)" "unprognostic (8.11e-2)" "unprognostic (5.86e-2)" "unprognostic (3.45e-1)" "unprognostic (2.73e-1)" "unprognostic (1.24e-2)" "unprognostic (1.05e-1)" "unprognostic (6.24e-3)" "unprognostic (7.92e-3)" "unprognostic (1.99e-1)" "unprognostic (1.03e-1)" "unprognostic (2.29e-1)" 0.6 1.1 0.6 0.2 0.4 0.4 1.5 0.3 1.6 43.1 0.0 0.6 0.4 0.5 0.4 239.5 1.8 0.7 0.9 0.8 0.8 3.7 1.7 1.1 0.7 1.4 1.3 0.3 1.5 0.6 7.3 0.3 0.6 2.6 0.1 0.6 29.9 0.5 0.4 34.4 0.8 0.0 1.0 0.7 2.0 4.1 0.9 0.3 2.4 0.0 14.3 1.2 57.7 0.5 25.1 2.4 1.8 3.9 0.0 0.1 5.3 0.4 0.4 0.5 0.2 1.3 28.9 1.3 1.2 0.3 0.7 33.3 0.5 7.0 0.0 2.7 1.8 0.3 30.6 16.8 0.9 0.2 1.4 0.4 3.5 0.9 0.2 1.3 0.3 1.4 0.6 3.1 1.6 49.5 0.7 1.0 0.7 4.8 3.0 2.4 2.8 3.5 0.6 1.6 0.4 1.8 4.5 3.5 0.9 1.5 7.7 0.4 1.0 1.1 0.9 3.2 0.6 1.9 1.7 1.2 1.4 1.3 1.4 0.2 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.6 0.4 0.3 1.6 0.8 0.8 1.4 1.3 0.6 1.0 0.9 0.5 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.7 0.5 0.4 1.5 2.5 5.5 0.0 0.6 0.1 0.4 0.0 4.6 0.5 2.1 0.2 0.3 0.0 0.0 0.3 5.8 0.2 0.1 3.1 1.7 0.0 0.6 0.7 0.8 0.2 0.0 0.3 0.6 0.0 0.3 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.5 0.0 0.0 0.0 58.0 1.1 0.4 0.1 0.2 1.6 0.9 0.0 0.6 0.0 0.3 0.3 3.0 1.1 66.0 0.0 0.0 0.1 0.9 0.5 1.7 CYTH4 "CYT4, cytohesin-4, PSCD4" ENSG00000100055 "Cytohesin 4" Q9UIA0 22 37282027-37315341 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 58.3;lymphoid tissue: 67.3" "Cell type enhanced" "Detected in many" "dendritic cells: 117.5;granulocytes: 57.0;Hofbauer cells: 76.8;Kupffer cells: 71.5;Langerhans cells: 87.5;Macrophages: 55.0;NK-cells: 120.5;T-cells: 43.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HL-60: 34.1;HMC-1: 141.1;THP-1: 95.2;U-266/70: 28.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004065, HPA071573" Approved Supported "Plasma membrane,Cytokinetic bridge,Centriolar satellite,Cytosol" Yes NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Cytokinetic bridge, Centriolar satellite, Cytosol" "HPA004065: , HPA071573: AB_2686418" "unprognostic (4.30e-3)" "unprognostic (1.65e-2)" "unprognostic (3.03e-2)" "unprognostic (9.28e-3)" "unprognostic (9.25e-2)" "unprognostic (1.69e-2)" "unprognostic (1.50e-1)" "unprognostic (5.84e-2)" "unprognostic (3.30e-3)" "unprognostic (1.23e-1)" "unprognostic (3.31e-2)" "unprognostic (8.42e-2)" "prognostic unfavorable (2.41e-8)" "unprognostic (3.70e-2)" "unprognostic (1.92e-2)" "unprognostic (5.56e-2)" "unprognostic (2.07e-1)" 21.5 8.8 4.9 67.3 4.5 58.3 5.1 4.4 8.5 5.3 6.0 10.7 8.5 4.4 1.6 6.1 4.8 16.4 5.6 4.7 5.6 4.1 5.7 18.9 57.0 8.8 7.4 3.4 2.5 2.1 2.9 28.0 7.8 3.6 10.0 0.3 7.3 4.3 2.2 2.2 15.2 12.9 6.7 59.2 11.5 2.7 9.7 25.6 3.0 5.1 40.3 23.2 2.5 9.1 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.8 9.3 0.3 0.0 2.5 0.1 0.0 0.6 0.0 5.3 0.0 9.8 0.0 0.0 0.0 34.1 141.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 23.2 0.0 0.0 0.5 13.5 0.0 0.1 1.0 1.3 0.2 19.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 95.2 0.3 0.0 0.1 0.1 0.0 28.4 4.0 4.5 18.5 11.5 0.2 15.8 62.6 87.5 55.4 102.5 39.0 30.3 30.5 44.8 47.5 31.8 30.0 38.3 199.1 45.0 129.4 113.8 30.7 76.2 4.9 4.5 4.4 8.5 4.7 5.6 8.8 7.4 7.8 6.7 9.7 9.1 1.1 3.2 8.4 0.0 37.0 2.4 0.8 0.0 0.6 0.1 0.7 1.5 2.0 0.0 1.8 0.0 0.0 0.5 117.5 0.1 0.0 0.0 0.4 0.1 0.2 2.5 0.0 2.5 0.2 0.2 0.6 1.9 2.0 0.1 57.0 0.0 2.2 1.1 76.8 0.0 0.2 0.2 0.0 71.5 87.5 0.9 0.6 55.0 7.2 24.4 42.7 0.0 120.5 0.5 0.0 0.8 0.0 0.0 25.1 0.3 0.0 0.8 0.0 0.1 0.0 0.9 1.0 0.0 0.2 0.3 2.3 1.0 43.9 0.0 0.2 0.5 CZIB "C1orf123, FLJ20580" ENSG00000162384 "CXXC motif containing zinc binding protein" Q9NWV4 1 53214099-53220634 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Adipocytes: 29.2;Cardiomyocytes: 45.8;Cytotrophoblasts: 60.7;Extravillous trophoblasts: 76.7;Fibroblasts: 22.2;Hofbauer cells: 66.5;Syncytiotrophoblasts: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043835 Uncertain Approved "Vesicles,Mitotic spindle,Cytosol" Yes No 320000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Vesicles, Mitotic spindle" "HPA043835: AB_10796797" "unprognostic (1.09e-2)" "unprognostic (5.91e-2)" "unprognostic (2.03e-2)" "unprognostic (4.55e-2)" "unprognostic (5.43e-2)" "unprognostic (1.53e-1)" "unprognostic (9.20e-3)" "unprognostic (2.27e-1)" "unprognostic (5.52e-2)" "unprognostic (9.37e-3)" "unprognostic (1.46e-1)" "unprognostic (3.05e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (6.31e-3)" "unprognostic (1.39e-1)" "unprognostic (1.32e-1)" "unprognostic (2.43e-1)" 55.8 35.5 56.1 22.3 58.0 21.9 49.4 57.2 74.6 53.6 56.9 66.5 22.5 57.1 39.8 32.3 52.3 30.2 52.5 57.7 56.6 39.4 43.5 33.1 30.0 57.9 56.6 47.2 25.1 34.6 28.5 30.6 57.0 41.0 34.8 21.6 24.8 45.4 76.5 26.2 31.6 59.2 57.1 32.5 40.3 31.0 57.4 36.3 35.1 65.3 29.7 57.7 37.6 59.0 32.6 34.7 44.7 41.0 101.6 129.1 39.4 47.8 50.4 47.3 50.8 29.6 27.5 50.1 39.0 58.1 45.8 12.6 27.9 46.9 57.0 65.0 47.5 51.0 24.9 45.0 100.0 59.5 32.1 84.6 50.3 50.6 53.3 71.5 78.5 61.0 53.7 13.7 60.1 54.6 73.5 55.6 74.8 39.7 54.3 52.8 56.8 39.7 55.8 32.6 37.6 36.1 45.1 40.9 47.7 72.2 29.2 59.8 49.3 54.5 31.9 38.2 47.2 19.5 30.7 57.3 43.9 58.5 42.8 60.7 56.6 58.6 50.9 72.3 46.9 46.9 49.8 53.6 68.8 45.1 55.0 54.9 22.8 59.0 60.3 46.3 68.2 51.1 56.1 58.0 57.2 74.6 57.7 56.6 57.9 56.6 57.0 57.1 57.4 59.0 29.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.8 0.0 0.0 0.0 0.0 60.7 8.2 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 76.7 22.2 0.0 0.0 0.0 0.0 0.0 0.0 66.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 46.7 1.3 0.0 0.0 0.0 DBF4 "ASK, chif, DBF4A, ZDBF1" ENSG00000006634 "DBF4 zinc finger" Q9UBU7 7 87876216-87909553 "Predicted intracellular proteins" "Cell cycle, DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 20 "testis: 15.1" "Group enriched" "Detected in all" 4 "Early spermatids: 468.6;Spermatocytes: 569.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042923 Supported "Nucleoplasm,Nuclear bodies" Yes Yes "Cluster 10: Basophils - Unknown function" "Cluster 74: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "HPA042923: AB_2678222" "unprognostic (2.48e-1)" "unprognostic (8.32e-2)" "unprognostic (1.15e-2)" "unprognostic (4.86e-3)" "unprognostic (2.81e-2)" "unprognostic (3.63e-1)" "prognostic unfavorable (4.45e-6)" "unprognostic (1.05e-1)" "prognostic unfavorable (6.86e-4)" "unprognostic (1.46e-3)" "unprognostic (1.05e-3)" "unprognostic (2.78e-3)" "prognostic unfavorable (6.42e-7)" "unprognostic (1.98e-2)" "unprognostic (2.40e-1)" "unprognostic (1.47e-1)" "unprognostic (1.30e-1)" 0.1 0.2 0.2 0.2 0.4 0.6 0.2 0.7 0.4 0.2 0.1 0.2 0.2 0.2 0.3 0.1 0.1 0.4 0.1 0.2 0.1 0.2 0.2 0.1 0.5 0.2 0.2 0.2 0.1 0.1 0.0 0.1 0.2 0.2 0.2 0.2 0.1 0.1 0.1 0.2 0.3 0.0 0.1 0.3 0.2 15.1 0.2 0.6 0.3 0.0 0.5 0.1 0.1 0.3 0.9 0.8 2.0 2.5 0.4 0.4 0.5 1.0 0.2 1.0 2.1 1.4 0.6 2.1 0.6 0.6 1.7 0.9 2.2 0.5 1.0 1.6 1.3 1.3 1.0 0.4 0.1 1.7 1.0 0.4 0.6 1.2 1.0 0.3 0.9 1.9 1.2 4.2 1.4 1.7 2.8 2.0 2.0 2.1 1.9 0.7 3.1 2.5 0.8 0.1 3.0 1.8 1.2 2.2 1.0 1.6 0.9 1.6 0.1 1.2 1.4 3.1 2.0 2.3 5.2 2.1 0.8 3.1 2.5 1.0 0.1 0.1 0.3 0.0 0.1 0.2 0.2 0.1 0.0 0.2 0.2 0.3 0.2 0.2 0.0 0.2 0.4 0.1 0.2 0.4 0.7 0.4 0.2 0.1 0.2 0.2 0.2 0.1 0.2 0.3 13.3 3.2 12.6 5.5 38.4 15.6 16.4 10.7 12.0 6.6 13.0 16.8 3.7 2.8 7.7 9.2 12.5 19.6 59.2 9.7 3.9 8.3 468.6 12.1 23.6 11.1 14.9 40.8 14.7 14.7 36.4 12.4 14.3 17.7 31.0 19.4 6.4 6.5 16.1 3.3 9.1 20.6 16.2 9.1 15.5 116.0 15.5 20.8 12.4 2.8 11.0 2.1 24.7 6.0 6.7 14.1 8.5 9.4 48.9 18.4 4.2 5.8 10.2 16.6 13.1 9.7 11.4 569.4 74.6 20.5 12.6 9.6 44.4 13.5 22.3 11.7 DCDC2 "DCDC2A, DFNB66, KIAA1154, NPHP19, RU2" ENSG00000146038 "Doublecortin domain containing 2" Q9UHG0 6 24171755-24358059 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Neurogenesis" "Ciliopathy, Deafness, Disease variant, Nephronophthisis, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 15.1;kidney: 23.2;pancreas: 26.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 62.9;Collecting duct cells: 79.1;Distal tubular cells: 56.7;Ductal cells: 135.9;Endometrial ciliated cells: 160.3;Glandular and luminal cells: 102.4;Proximal tubular cells: 54.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 71.8;EFO-21: 48.3;Hep G2: 82.3;RPTEC TERT1: 254.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA031582, HPA031583, HPA031584" Enhanced Supported "Microtubules,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Cytosol "Microtubules, Mitotic spindle, Centriolar satellite" "HPA031582: AB_10600901, HPA031583: AB_2673944, HPA031584: AB_2673945" "unprognostic (8.65e-2)" "unprognostic (2.07e-2)" "unprognostic (1.66e-1)" "unprognostic (6.70e-2)" "unprognostic (1.08e-2)" "unprognostic (3.22e-1)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (2.90e-1)" "unprognostic (7.87e-2)" "unprognostic (1.81e-1)" "unprognostic (1.09e-1)" "unprognostic (2.67e-2)" "unprognostic (5.22e-2)" "unprognostic (1.16e-1)" "unprognostic (2.12e-2)" "unprognostic (2.99e-2)" 0.0 1.3 0.8 0.0 1.2 0.1 4.4 0.3 0.8 1.6 15.1 0.7 0.6 4.4 5.3 0.0 7.6 3.9 0.0 0.8 1.0 23.2 2.2 3.4 0.0 2.2 2.7 0.2 26.2 8.2 1.2 0.6 1.7 1.2 0.6 1.4 0.4 2.3 0.3 0.1 0.1 0.1 2.0 0.1 1.8 3.7 1.1 0.1 8.2 0.2 0.0 0.4 0.0 1.6 0.0 8.8 0.5 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 71.8 0.2 0.0 48.3 0.0 0.1 0.0 0.0 0.1 0.1 0.0 8.2 0.0 0.0 82.3 0.0 0.0 0.0 0.0 0.0 9.7 0.0 1.4 0.0 0.2 0.1 0.0 0.3 10.8 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 254.5 0.3 5.2 0.5 0.0 1.3 0.0 0.2 12.3 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.5 0.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.8 1.2 0.3 0.8 0.8 1.0 2.2 2.7 1.7 2.0 1.1 1.6 0.2 19.2 14.4 3.9 1.4 0.1 0.6 0.3 0.0 0.0 20.3 11.7 0.3 62.9 6.1 79.1 0.0 0.4 0.0 1.2 56.7 135.9 40.1 160.3 5.3 0.4 3.6 0.0 11.3 8.4 0.0 1.3 3.6 102.4 0.0 4.1 0.0 1.0 0.5 0.0 8.3 2.9 0.0 0.0 0.0 14.6 0.3 1.0 0.0 1.0 2.0 2.3 0.0 1.0 0.5 27.9 4.1 0.4 0.0 1.3 0.0 54.3 37.1 0.1 0.0 0.0 2.4 32.3 2.6 0.0 0.1 0.1 1.1 5.6 2.7 0.9 DCTN1 ENSG00000204843 "Dynactin subunit 1" Q14203 2 74361154-74392087 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transport" "Amyotrophic lateral sclerosis, Cancer-related genes, Neurodegeneration, Neuropathy, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009108, HPA034635, HPA071875" Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes No 250000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB009108: AB_2090601, HPA034635: AB_2674256, HPA071875: " "unprognostic (1.14e-1)" "unprognostic (7.19e-2)" "unprognostic (1.33e-3)" "unprognostic (4.08e-2)" "unprognostic (1.20e-1)" "unprognostic (2.67e-1)" "unprognostic (4.61e-3)" "unprognostic (2.11e-2)" "unprognostic (2.79e-1)" "unprognostic (3.73e-3)" "unprognostic (1.87e-1)" "unprognostic (2.26e-1)" "prognostic favorable (2.34e-7)" "unprognostic (5.41e-2)" "unprognostic (3.11e-1)" "unprognostic (7.86e-3)" "unprognostic (1.12e-3)" 43.3 40.0 90.5 27.0 94.7 23.7 37.4 76.4 113.2 44.3 20.8 51.3 22.2 51.4 17.0 42.6 38.7 28.2 82.6 99.9 80.1 27.6 18.2 36.0 22.8 110.9 85.1 39.2 28.6 118.0 61.2 32.6 112.6 30.0 25.5 43.5 56.3 38.0 87.6 44.2 32.2 49.9 76.0 26.5 39.5 51.3 101.9 34.7 31.3 63.4 24.6 47.6 39.0 116.2 65.0 74.7 68.4 71.9 122.5 90.7 55.2 102.0 105.2 127.0 89.9 99.9 48.6 88.8 40.8 213.0 70.1 63.5 84.3 129.5 96.1 111.2 85.0 92.5 55.6 84.7 94.4 50.7 109.3 109.6 62.0 138.3 82.3 86.9 110.3 79.4 40.3 61.4 97.3 55.6 92.8 52.5 74.0 78.6 78.3 82.3 120.1 63.8 70.2 39.6 83.3 74.1 57.1 67.7 60.6 59.0 43.5 36.5 84.3 115.0 82.7 50.0 77.2 37.8 32.7 78.9 107.6 81.4 82.5 8.3 11.3 12.7 14.4 13.0 11.7 10.1 8.2 10.8 11.2 6.8 5.6 6.3 9.2 9.2 15.6 8.8 7.7 16.5 90.5 94.7 76.4 113.2 99.9 80.1 110.9 85.1 112.6 76.0 101.9 116.2 28.6 32.1 25.4 9.8 23.2 10.1 10.3 19.1 25.6 27.2 19.6 17.8 56.4 18.6 20.0 29.5 25.0 29.8 19.4 41.0 19.6 22.5 7.3 21.5 32.8 26.6 16.7 27.3 28.4 19.9 27.1 25.1 49.5 27.8 29.2 30.8 29.6 19.9 28.8 90.9 26.7 31.8 24.4 21.0 11.3 9.3 44.7 21.2 16.0 8.4 27.3 14.9 23.7 12.1 29.7 26.6 33.6 51.9 24.7 9.6 34.2 19.6 19.4 45.5 19.7 28.3 30.0 40.6 38.5 29.0 11.8 25.2 20.0 33.9 24.9 10.7 DDR2 "NTRKR3, TKT, TYRO10" ENSG00000162733 "Discoidin domain receptor tyrosine kinase 2" Q16832 1 162631373-162787405 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Osteogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 89.8;Fibroblasts: 116.5;Leydig cells: 63.0;Peritubular cells: 88.4;Skeletal myocytes: 98.2;Smooth muscle cells: 78.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 233.3;ASC TERT1: 214.4;BJ hTERT+: 163.4;fHDF/TERT166: 137.6;HSkMC: 157.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070112 Approved "Plasma membrane,Actin filaments" Yes No 770000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Actin filaments" "HPA070112: AB_2686229" "unprognostic (4.12e-2)" "unprognostic (2.73e-1)" "unprognostic (6.97e-3)" "unprognostic (4.52e-2)" "unprognostic (1.17e-1)" "unprognostic (8.16e-2)" "unprognostic (1.81e-1)" "unprognostic (1.19e-1)" "unprognostic (6.62e-2)" "unprognostic (2.24e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.73e-7)" "unprognostic (1.56e-3)" "unprognostic (8.26e-3)" "unprognostic (7.57e-2)" "unprognostic (4.10e-3)" 59.8 64.3 13.2 15.8 11.3 0.3 25.2 10.4 9.2 33.7 51.5 54.7 5.8 26.2 13.2 18.1 22.4 23.8 24.1 12.6 24.5 6.4 5.4 14.5 9.1 37.0 22.1 37.4 3.7 2.5 5.4 10.6 31.7 17.3 14.1 5.1 9.8 29.2 4.9 9.7 17.6 42.8 17.8 5.8 20.4 3.9 21.0 3.3 12.9 19.3 6.9 23.2 23.6 25.2 0.3 0.0 0.2 63.2 233.3 214.4 1.0 92.2 163.4 41.5 56.8 0.0 0.2 0.0 0.1 137.6 8.9 0.1 0.3 0.4 54.0 42.9 0.3 0.0 0.4 0.1 103.9 0.2 0.2 157.0 0.4 73.1 2.2 65.8 46.0 0.4 0.6 16.8 36.9 0.1 0.0 0.3 0.4 0.1 0.3 0.1 24.1 0.7 0.2 0.2 0.3 35.4 0.2 0.1 2.9 3.6 0.2 0.3 2.1 58.5 13.8 29.1 12.6 2.6 4.0 0.1 56.3 0.1 62.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 11.3 10.4 9.2 12.6 24.5 37.0 22.1 31.7 17.8 21.0 25.2 23.4 3.2 2.3 53.2 2.5 12.6 3.9 0.8 1.2 3.0 6.0 15.6 31.3 1.5 1.1 0.0 0.0 0.5 1.7 3.2 0.0 0.4 8.9 5.0 89.8 22.3 1.2 0.0 13.1 1.8 0.5 116.5 2.6 8.2 1.3 16.7 30.0 3.5 1.2 0.0 26.2 1.0 0.0 1.9 19.3 7.1 63.0 3.1 23.2 29.0 0.0 16.5 2.1 6.0 5.6 1.8 4.4 88.4 5.6 5.9 1.2 2.1 2.4 3.0 39.5 98.2 78.3 1.0 0.9 2.0 8.7 1.0 2.5 34.2 0.8 4.2 DDX18 "Has1, MrDb" ENSG00000088205 "DEAD-box helicase 18" Q9NVP1 2 117814691-117832377 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 376.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035400, HPA041056" Approved Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 17000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim, Mitotic chromosome" "HPA035400: AB_10672091, HPA041056: AB_2677277" "unprognostic (1.44e-1)" "unprognostic (2.22e-2)" "unprognostic (5.63e-2)" "prognostic unfavorable (2.64e-4)" "unprognostic (2.06e-1)" "unprognostic (1.77e-3)" "prognostic unfavorable (3.07e-4)" "unprognostic (8.80e-2)" "unprognostic (1.66e-3)" "unprognostic (1.44e-1)" "unprognostic (1.42e-2)" "unprognostic (4.94e-2)" "unprognostic (8.51e-2)" "unprognostic (1.45e-1)" "unprognostic (1.53e-1)" "unprognostic (7.28e-2)" "unprognostic (5.65e-2)" 25.3 21.4 14.9 30.2 15.9 21.8 32.7 16.1 18.0 23.4 15.1 28.3 22.4 30.0 22.9 24.8 23.6 22.2 21.2 14.1 15.9 27.0 35.2 24.8 41.1 15.7 15.2 25.5 21.1 21.4 10.8 26.2 16.1 23.2 31.0 19.4 19.3 23.0 18.6 22.9 23.4 26.3 16.6 32.3 22.8 20.6 15.1 34.5 30.2 18.3 41.7 33.2 17.3 19.0 94.0 41.9 61.3 55.5 35.5 31.9 101.0 54.7 43.0 73.7 64.6 104.2 60.6 137.8 85.9 45.6 68.0 71.1 120.3 70.7 108.0 70.6 83.9 132.0 36.9 105.1 49.5 178.4 66.0 33.4 63.9 93.7 94.3 37.6 44.9 70.3 146.5 58.4 57.1 58.6 98.2 92.6 154.4 79.1 62.3 84.4 95.8 121.3 48.8 55.2 58.8 99.3 62.7 69.2 73.4 62.1 43.9 96.7 34.9 65.6 96.5 46.8 99.5 66.3 87.9 376.0 48.2 82.9 30.1 11.7 23.0 16.3 24.9 28.9 32.0 37.4 29.8 28.9 20.7 30.3 35.6 31.7 5.8 29.7 33.1 33.7 25.7 32.1 14.9 15.9 16.1 18.0 14.1 15.9 15.7 15.2 16.1 16.6 15.1 19.0 144.4 96.1 62.5 24.8 153.9 192.7 114.4 149.4 100.2 150.5 82.8 94.5 50.4 101.5 103.8 121.4 83.4 110.3 140.6 69.0 117.4 125.4 17.1 92.2 125.1 109.1 56.9 76.4 24.3 115.2 120.9 98.2 63.2 102.8 110.3 71.8 107.1 195.6 87.9 82.4 28.0 108.0 109.9 104.8 100.8 17.7 106.6 100.6 92.5 20.6 117.1 70.3 135.9 26.7 39.1 130.0 68.8 103.8 103.3 118.1 53.3 186.5 90.6 132.9 65.7 158.7 110.1 138.6 129.9 81.4 160.5 88.8 143.2 67.4 114.6 65.3 DDX21 "GURDB, RH-II/GU" ENSG00000165732 "DExD-box helicase 21" Q9NR30 10 68956170-68985068 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, rRNA processing, Transcription" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 589.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036592, HPA036593" Enhanced Enhanced "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes No 40000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA036592: AB_10673625, HPA036593: AB_2675208" "unprognostic (3.04e-1)" "unprognostic (6.81e-3)" "unprognostic (1.13e-2)" "unprognostic (1.21e-2)" "unprognostic (1.75e-2)" "unprognostic (6.71e-3)" "unprognostic (1.34e-2)" "unprognostic (1.99e-2)" "unprognostic (1.29e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (3.12e-4)" "unprognostic (1.64e-1)" "unprognostic (1.39e-2)" "unprognostic (9.33e-2)" "unprognostic (5.41e-2)" "unprognostic (1.24e-2)" "unprognostic (5.74e-3)" 55.9 27.9 7.9 52.7 8.8 103.5 36.2 8.9 9.3 22.0 7.7 26.5 25.5 25.2 13.4 40.3 24.0 32.4 21.9 7.4 9.7 30.0 42.1 31.5 50.0 10.8 10.1 20.1 45.7 24.5 12.9 38.0 11.0 19.0 32.0 8.1 20.5 17.5 47.9 30.1 21.8 28.4 10.7 30.2 26.4 22.5 8.8 33.6 25.1 26.9 51.0 81.7 23.5 11.3 194.4 112.5 64.5 199.7 56.7 74.4 135.6 129.8 104.3 163.8 138.3 366.7 128.8 289.5 77.8 108.2 77.2 168.1 250.4 161.8 217.5 90.7 176.1 203.2 76.9 153.3 121.2 488.9 184.7 76.8 205.2 196.2 324.5 76.1 121.3 106.8 393.8 140.5 116.8 88.1 192.9 106.1 176.3 91.8 236.8 170.1 105.3 143.0 108.2 102.7 132.5 141.6 116.6 254.8 155.5 76.8 144.9 101.1 125.6 95.5 136.0 129.8 230.7 160.4 228.2 418.2 79.3 362.4 66.5 7.6 10.9 20.4 8.7 17.1 15.9 14.0 11.4 11.8 13.0 12.3 10.6 11.8 4.9 9.4 21.2 12.1 9.2 7.5 7.9 8.8 8.9 9.3 7.4 9.7 10.8 10.1 11.0 10.7 8.8 11.3 199.4 102.5 141.6 8.1 243.7 550.2 346.2 103.8 174.2 25.9 159.9 113.7 74.2 94.4 144.1 71.7 41.7 80.8 139.5 134.0 72.4 141.2 50.8 116.7 260.7 196.7 86.7 98.6 18.5 187.8 151.8 162.2 120.8 201.8 168.5 57.1 104.2 215.3 112.4 25.2 16.0 202.7 67.1 154.5 266.8 19.7 89.5 199.1 124.5 12.2 138.1 25.8 64.9 13.6 18.2 222.9 77.7 77.1 148.9 465.3 59.9 128.2 72.8 29.8 26.3 302.6 174.9 105.5 114.8 224.8 589.7 137.5 159.6 99.4 210.7 375.5 DDX56 NOH61 ENSG00000136271 "DEAD-box helicase 56" Q9NY93 7 44565804-44575051 "Enzymes, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019749, CAB037320" Uncertain Supported "Nucleoli,Mitotic chromosome" Yes NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoli "Mitotic chromosome" "CAB037320: , HPA019749: AB_1847579" "unprognostic (3.28e-1)" "unprognostic (1.05e-1)" "unprognostic (5.00e-2)" "unprognostic (1.93e-1)" "unprognostic (6.08e-3)" "unprognostic (2.12e-3)" "prognostic unfavorable (1.38e-5)" "unprognostic (5.17e-2)" "unprognostic (2.76e-1)" "unprognostic (7.07e-2)" "unprognostic (1.00e-2)" "unprognostic (6.01e-3)" "prognostic unfavorable (8.41e-7)" "unprognostic (2.60e-1)" "unprognostic (2.88e-2)" "unprognostic (1.50e-1)" "unprognostic (4.90e-2)" 21.3 21.8 24.8 21.5 25.6 16.6 17.1 25.5 29.0 19.2 25.3 18.6 20.8 15.4 17.3 25.9 27.2 15.8 20.3 25.1 25.3 16.2 30.1 15.7 29.4 25.6 25.2 22.1 28.2 27.1 7.9 20.1 25.7 18.2 15.7 7.3 24.6 20.2 27.4 32.2 16.4 21.2 25.2 19.5 20.8 10.4 25.2 24.5 23.5 21.5 27.1 28.4 7.3 26.0 69.5 118.8 32.0 70.0 36.6 40.3 62.3 60.9 43.7 107.6 83.9 139.2 90.7 109.8 65.0 59.4 143.5 111.4 70.9 97.5 38.5 45.9 99.2 64.3 90.9 86.1 59.9 77.0 66.4 57.9 78.8 105.8 82.2 35.5 62.0 55.8 150.2 42.8 78.3 103.7 67.3 104.4 108.8 127.8 103.6 70.7 54.3 76.7 69.8 65.4 68.8 90.6 64.2 199.4 58.9 21.3 120.6 105.5 52.4 71.0 86.0 52.6 155.1 88.7 135.0 167.1 75.2 115.1 146.1 36.3 50.8 21.1 37.6 66.3 47.7 48.3 40.9 41.6 63.8 55.0 49.2 38.7 3.6 63.2 67.7 34.8 44.9 59.7 24.8 25.6 25.5 29.0 25.1 25.3 25.6 25.2 25.7 25.2 25.2 26.0 21.5 16.0 29.0 13.1 22.8 17.1 23.9 45.1 21.1 26.6 18.4 14.7 12.3 11.5 40.3 22.0 14.6 57.0 19.1 29.0 27.4 39.4 41.4 21.0 21.1 26.4 18.5 35.8 6.1 32.3 48.5 24.6 30.5 20.6 28.5 35.3 16.8 30.1 35.4 6.7 8.0 24.9 38.7 13.2 17.5 37.5 21.1 17.9 14.2 3.7 28.8 22.4 23.7 6.6 6.2 37.5 18.8 19.9 18.2 24.8 37.2 63.0 31.8 26.9 13.1 22.4 25.1 36.2 25.6 30.1 19.9 47.2 23.6 40.3 36.8 21.3 DEF6 "IBP, SLAT, SWAP70L" ENSG00000023892 "DEF6 guanine nucleotide exchange factor" Q9H4E7 6 35297818-35321771 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 63.2;lymphoid tissue: 62.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 94.0;Late spermatids: 151.4;NK-cells: 88.6;T-cells: 78.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "JURKAT: 83.3;MOLT-4: 75.5;NB-4: 99.3;REH: 68.8;THP-1: 78.9;U-937: 117.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA038975, HPA038976" Enhanced Enhanced Nucleoplasm Yes NA "Cluster 5: Granulocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA038975: AB_10697544, HPA038976: AB_10673409" "prognostic favorable (3.02e-6)" "prognostic favorable (1.08e-4)" "prognostic unfavorable (1.71e-4)" "prognostic favorable (2.37e-4)" "unprognostic (1.93e-1)" "unprognostic (3.63e-3)" "unprognostic (2.24e-1)" "unprognostic (1.53e-2)" "unprognostic (1.64e-1)" "unprognostic (2.12e-1)" "unprognostic (2.14e-1)" "unprognostic (6.21e-3)" "prognostic unfavorable (1.02e-8)" "unprognostic (1.78e-1)" "unprognostic (2.91e-2)" "unprognostic (1.38e-1)" "unprognostic (1.45e-3)" 5.8 3.6 5.9 33.5 5.9 63.2 6.0 6.3 7.2 8.0 7.3 9.8 10.2 2.8 8.5 28.2 4.4 7.2 2.6 5.9 6.6 4.7 5.2 14.7 48.6 8.7 7.0 3.1 21.6 1.3 8.3 7.7 8.0 21.0 7.4 2.2 15.8 4.8 1.7 28.5 30.7 3.5 7.7 62.9 16.3 26.7 8.1 50.2 8.3 1.1 38.1 10.2 16.5 8.8 24.0 0.0 0.8 0.6 0.1 0.3 29.0 2.6 3.6 0.6 0.7 1.5 10.0 28.1 8.3 1.3 0.1 15.5 0.0 19.6 0.4 1.0 1.1 31.7 0.4 12.6 0.7 57.5 40.0 4.5 24.6 0.3 22.0 0.1 0.0 83.3 14.3 65.7 0.1 12.3 75.5 99.3 1.3 3.0 2.8 68.8 0.6 38.4 2.5 17.8 0.4 0.2 2.1 5.8 5.5 1.1 15.9 78.9 3.8 0.3 0.6 0.1 0.3 37.2 37.1 23.3 0.0 117.7 0.2 49.2 39.5 119.7 78.6 29.7 62.4 34.2 63.3 76.8 55.2 31.3 65.1 65.2 69.3 72.9 27.8 36.6 73.1 64.3 5.9 5.9 6.3 7.2 5.9 6.6 8.7 7.0 8.0 7.7 8.1 8.8 1.7 6.4 8.0 1.3 49.2 11.9 16.9 15.0 20.5 2.5 5.4 7.2 0.8 2.8 8.2 5.5 0.0 25.0 52.3 4.2 0.0 0.9 56.3 2.2 0.8 3.1 4.2 6.7 2.0 10.0 17.2 2.2 26.0 3.0 17.7 1.5 2.9 0.9 94.0 3.3 1.0 9.9 2.0 28.0 26.4 151.4 2.8 31.7 7.2 17.8 30.0 0.8 88.6 0.5 0.5 8.0 8.9 1.9 57.9 6.0 3.1 0.3 5.8 1.7 0.0 0.6 1.2 40.0 0.9 20.0 11.8 12.6 78.3 1.0 9.1 13.0 DEFA5 "DEF5, HD-5" ENSG00000164816 "Defensin alpha 5" Q01523 8 7055304-7056739 "Plasma proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 768 "intestine: 9759.8" "Group enriched" "Detected in some" 4 "Proximal enterocytes: 1740.2;Undifferentiated cells: 1753.0" "Cancer enhanced" "Detected in many" "cervical cancer: 181.1;colorectal cancer: 147.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "BEWO: 28.3;NB-4: 24.2;RPMI-8226: 26.6;SH-SY5Y: 19.6;U-2197: 8.5" "HPA015309, HPA015775, CAB069919" Enhanced Approved Vesicles,Midbody "Secreted to digestive system" Yes NA 110000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 45: Enterocytes - Digestion" Vesicles Midbody "CAB069919: AB_905358, HPA015309: , HPA015775: AB_1847594" "prognostic favorable (9.44e-5)" "unprognostic (3.91e-2)" 0.3 0.4 0.1 12.7 0.1 0.2 0.5 0.1 0.5 0.0 0.1 56.6 5185.1 3.9 0.1 0.8 0.0 0.0 0.4 0.1 0.2 0.2 1.1 0.4 6.0 0.1 0.2 0.4 0.8 0.0 1.1 0.0 0.2 0.7 0.2 0.1 0.7 0.0 0.3 0.3 9759.8 0.1 0.1 0.4 0.9 0.8 0.2 0.4 0.3 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 28.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.2 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 2.5 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.5 0.1 0.2 0.1 0.2 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.3 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.1 325.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.1 399.9 0.0 0.0 0.0 1740.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.4 0.0 1753.0 0.0 DENND4A "IRLB, MYCPBP" ENSG00000174485 "DENN domain containing 4A" Q7Z401 15 65658046-65792293 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 59.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 195.4;Oligodendrocyte precursor cells: 176.5;Oligodendrocytes: 180.2;Rod photoreceptor cells: 155.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 29.9" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065343 Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 21: B-cells - Adaptive immune response" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA065343: AB_2685476" "unprognostic (1.10e-1)" "unprognostic (8.43e-2)" "unprognostic (4.96e-2)" "unprognostic (1.60e-1)" "unprognostic (1.31e-1)" "unprognostic (3.29e-1)" "unprognostic (8.02e-2)" "unprognostic (2.30e-2)" "unprognostic (8.88e-2)" "unprognostic (2.28e-1)" "unprognostic (1.82e-1)" "unprognostic (1.38e-1)" "unprognostic (1.66e-1)" "unprognostic (7.83e-2)" "unprognostic (3.45e-1)" "unprognostic (2.24e-1)" "unprognostic (3.48e-1)" 6.2 9.8 4.0 11.4 6.5 33.8 6.8 29.9 7.5 7.4 11.2 6.6 5.8 8.8 5.1 6.6 7.2 11.2 5.1 5.6 5.1 7.9 16.8 9.5 19.7 3.5 4.7 12.8 15.5 10.1 8.4 8.5 4.7 6.0 6.8 59.3 6.1 5.6 9.2 6.5 6.3 7.4 4.2 12.4 8.9 7.9 3.3 12.7 9.3 7.8 18.2 10.2 4.5 7.6 9.9 9.6 4.9 5.1 14.3 15.9 5.9 10.1 13.9 6.8 9.9 5.5 7.8 52.0 6.8 15.1 8.4 18.1 9.7 9.2 12.0 56.7 11.2 49.4 11.7 10.4 8.3 16.8 16.7 10.6 10.3 9.5 20.0 12.0 18.5 11.4 15.2 31.5 7.9 5.2 8.1 9.1 1.5 30.5 6.9 3.9 17.2 45.1 8.0 19.0 7.7 7.0 9.8 6.9 8.9 5.8 6.7 43.1 19.6 9.3 10.3 16.7 14.2 16.8 20.1 19.3 13.1 36.2 7.8 3.2 2.6 5.2 3.6 1.0 5.5 5.4 3.1 4.6 2.3 6.1 3.2 3.1 1.4 3.5 0.9 0.9 3.3 1.5 4.0 6.5 29.9 7.5 5.6 5.1 3.5 4.7 4.7 4.2 3.3 7.6 22.7 16.0 23.1 126.7 81.5 27.9 29.8 7.9 36.5 73.8 23.9 12.2 12.3 20.0 15.2 9.2 60.5 5.6 47.8 5.8 0.0 10.1 2.4 29.3 22.2 23.7 17.4 83.1 195.4 13.0 6.8 22.4 25.0 46.1 48.8 10.5 21.0 25.9 20.4 111.0 140.3 9.7 0.0 19.0 47.5 3.0 13.1 42.2 24.9 145.2 24.5 26.9 20.6 176.5 180.2 12.0 10.1 12.4 55.1 20.2 6.4 9.8 18.1 155.9 6.6 37.9 15.7 11.3 10.9 18.7 17.0 12.6 56.5 13.2 10.0 17.3 DEPDC7 ENSG00000121690 "DEP domain containing 7" Q96QD5 11 33015876-33033582 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 29.0;kidney: 19.6;liver: 74.0;testis: 28.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 34.8;Early spermatids: 153.3;Extravillous trophoblasts: 47.0;Proximal enterocytes: 33.2;Spermatocytes: 42.3" "Cancer enhanced" "Detected in many" "liver cancer: 6.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 6.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 53.7;RH-30: 40.1;SiHa: 37.3;SK-MEL-30: 34.4;U-2197: 34.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA015800 Approved Nucleoplasm,Nucleoli,Cytosol Yes No "Cluster 2: Granulocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoli "Nucleoplasm, Cytosol" "HPA015800: AB_1847610" "unprognostic (2.34e-1)" "unprognostic (5.57e-2)" "unprognostic (1.27e-1)" "unprognostic (2.27e-1)" "unprognostic (2.66e-2)" "unprognostic (7.26e-2)" "prognostic favorable (7.26e-4)" "unprognostic (1.80e-1)" "unprognostic (1.22e-1)" "unprognostic (2.92e-1)" "unprognostic (1.17e-3)" "unprognostic (8.99e-2)" "unprognostic (1.89e-2)" "unprognostic (9.30e-2)" "unprognostic (8.09e-3)" "unprognostic (2.64e-1)" "unprognostic (2.94e-2)" 0.6 0.8 2.5 1.9 3.2 1.8 0.9 2.9 3.7 2.8 2.7 4.6 24.6 1.0 2.2 4.4 0.9 4.4 1.1 2.6 2.7 19.6 74.0 0.9 0.7 3.2 2.7 1.6 3.8 2.3 0.8 1.5 3.0 1.9 5.1 0.1 2.0 1.5 4.9 6.0 29.0 1.7 2.8 0.3 3.0 28.2 2.7 2.9 0.5 0.9 1.5 1.2 3.4 4.9 9.4 5.2 7.3 3.3 3.8 3.6 4.9 16.2 5.4 9.8 13.0 13.5 0.9 0.0 3.7 16.2 4.5 9.4 10.8 3.8 11.5 0.0 14.9 2.5 16.1 19.3 3.2 9.1 10.9 4.6 5.7 5.7 4.2 5.3 0.0 0.0 6.2 0.0 53.7 1.0 0.0 14.6 4.8 7.7 0.0 0.0 40.1 0.1 3.2 1.3 1.6 4.2 37.3 6.6 34.4 5.1 1.7 4.7 0.0 6.3 10.4 34.1 10.6 0.0 0.0 0.1 2.3 0.0 31.5 4.1 0.5 6.7 0.2 0.1 0.0 0.0 0.4 0.2 3.2 0.0 1.9 2.1 0.0 2.4 0.0 1.2 0.0 0.4 2.5 3.2 2.9 3.7 2.6 2.7 3.2 2.7 3.0 2.8 2.7 4.9 0.2 0.0 0.0 1.0 0.0 34.8 12.8 4.5 12.5 0.0 0.2 0.6 0.1 1.5 0.9 0.0 0.0 0.5 0.5 6.0 3.9 0.9 153.3 0.2 0.2 0.3 3.5 3.2 0.1 0.6 47.0 1.6 0.0 0.1 2.5 0.1 1.4 22.6 3.1 0.0 0.4 2.4 0.0 0.6 9.5 16.3 1.5 1.7 1.8 3.7 1.2 0.0 0.0 3.5 10.4 0.8 0.6 1.2 0.1 2.4 33.2 18.4 0.9 0.0 0.0 4.5 1.4 42.3 6.5 6.6 7.4 1.5 0.7 0.2 2.4 1.6 DESI1 "D15Wsu75e, DESI-1, FAM152B, POST, PPPDE2" ENSG00000100418 "Desumoylating isopeptidase 1" Q6ICB0 22 41598028-41621043 "Predicted intracellular proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 761.4;Late spermatids: 415.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053415 Approved Approved "Cytokinetic bridge,Cytosol" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "Cytokinetic bridge" "HPA053415: AB_2682141" "unprognostic (1.07e-1)" "unprognostic (2.07e-1)" "unprognostic (1.83e-2)" "prognostic favorable (7.70e-4)" "unprognostic (2.31e-2)" "unprognostic (6.16e-3)" "unprognostic (8.75e-3)" "unprognostic (9.27e-2)" "unprognostic (3.97e-2)" "unprognostic (6.27e-2)" "unprognostic (1.80e-2)" "unprognostic (1.42e-1)" "unprognostic (2.31e-3)" "unprognostic (2.65e-2)" "unprognostic (1.55e-1)" "unprognostic (8.18e-2)" "unprognostic (1.10e-1)" 11.9 18.5 34.3 10.4 36.0 7.5 10.9 37.1 36.6 10.7 23.6 13.3 11.6 11.2 11.3 26.4 10.2 8.9 38.1 34.4 37.5 22.3 47.3 14.7 11.6 36.1 37.9 12.4 12.5 13.1 12.2 9.3 35.5 13.0 10.6 12.9 12.0 10.6 16.1 15.5 12.6 11.3 34.9 13.5 16.4 18.7 38.6 8.8 9.2 17.6 13.6 12.7 11.9 35.3 16.7 17.4 17.0 23.4 23.5 28.0 9.6 33.0 21.0 30.0 21.9 23.2 10.4 63.2 22.2 38.2 15.7 23.8 45.7 36.8 31.1 28.6 34.7 14.2 32.5 19.7 28.8 56.4 18.4 24.1 42.2 36.8 34.1 24.3 45.8 21.7 42.0 69.5 24.0 21.2 12.9 17.2 16.8 62.2 26.0 17.3 7.2 65.2 38.0 10.5 12.1 6.3 31.8 34.5 23.0 19.3 11.4 18.3 46.8 22.0 16.0 23.4 16.3 25.4 21.1 29.7 54.4 24.4 29.7 9.1 6.6 7.8 3.3 9.0 4.3 4.1 4.0 3.9 5.2 3.7 3.5 4.3 3.8 2.1 6.2 3.0 5.3 4.2 34.3 36.0 37.1 36.6 34.4 37.5 36.1 37.9 35.5 34.9 38.6 35.3 21.2 9.6 18.9 10.7 27.1 8.7 36.6 42.1 13.1 19.8 29.7 29.8 55.2 18.6 21.7 9.2 6.2 31.1 15.0 29.0 39.2 50.8 761.4 29.5 24.7 24.1 19.7 11.8 13.9 30.2 39.5 17.6 19.4 55.0 10.8 27.6 19.6 72.9 50.4 21.9 18.1 19.9 22.4 28.1 18.6 415.8 19.0 33.8 14.2 6.5 49.4 18.6 30.9 11.6 13.3 50.0 29.5 10.5 46.5 111.0 80.1 53.7 10.8 11.4 26.3 14.3 24.3 149.4 30.7 43.6 13.2 83.6 22.4 28.9 26.3 72.3 DET1 FLJ10103 ENSG00000140543 "DET1 partner of COP1 E3 ubiquitin ligase" Q7L5Y6 15 88494440-88546681 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA048873 Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" Microtubules "Nucleoplasm, Cytokinetic bridge" "HPA048873: AB_2680541" "unprognostic (9.21e-2)" "unprognostic (1.83e-1)" "unprognostic (2.34e-1)" "unprognostic (1.26e-1)" "unprognostic (3.17e-1)" "unprognostic (1.86e-1)" "unprognostic (1.20e-2)" "unprognostic (6.64e-2)" "unprognostic (1.84e-1)" "unprognostic (4.01e-2)" "unprognostic (1.52e-1)" "unprognostic (4.00e-2)" "unprognostic (2.82e-3)" "unprognostic (2.62e-2)" "unprognostic (1.20e-1)" "unprognostic (8.69e-2)" "unprognostic (4.67e-2)" 3.7 5.2 2.5 2.0 2.8 1.2 3.6 2.7 2.7 6.0 3.2 4.2 3.5 6.7 5.4 2.2 5.6 3.0 5.6 2.5 2.6 3.2 2.7 2.1 2.9 2.7 2.5 10.3 3.6 3.7 3.7 3.5 2.8 4.1 3.2 5.0 4.1 3.8 9.7 2.6 3.2 5.5 2.4 2.5 3.4 1.5 2.6 5.6 4.1 11.7 3.0 4.5 3.3 3.2 1.7 6.2 8.6 6.0 3.4 6.0 1.1 5.4 6.1 4.5 5.1 1.0 4.8 3.3 4.1 7.3 4.5 2.4 8.7 1.3 3.9 0.2 5.9 6.9 3.1 1.5 6.7 2.5 1.1 5.0 5.9 1.9 6.9 4.4 3.8 2.9 8.5 3.8 6.7 2.6 3.2 2.8 3.6 2.6 1.8 4.2 6.9 3.8 2.4 5.3 3.0 4.9 6.5 2.0 14.9 5.6 2.9 5.2 3.0 5.1 3.7 4.8 5.4 2.3 1.4 2.1 5.4 4.3 4.5 0.0 2.3 1.6 2.2 3.4 1.4 1.8 1.7 1.9 3.7 2.2 2.6 1.9 0.3 1.4 2.3 1.9 2.4 1.3 2.5 2.8 2.7 2.7 2.5 2.6 2.7 2.5 2.8 2.4 2.6 3.2 3.5 3.2 2.7 6.8 3.5 0.6 2.0 3.7 4.6 11.5 4.3 3.8 2.3 1.5 2.1 3.7 10.4 7.2 1.7 2.1 1.9 3.4 1.2 3.4 6.1 2.3 3.0 5.5 5.7 3.9 6.3 4.9 2.0 2.4 0.0 10.6 2.2 2.8 4.4 6.7 6.8 2.7 2.0 1.6 2.2 0.6 4.4 2.5 3.6 3.7 4.7 7.1 2.1 6.0 9.5 3.1 1.0 3.8 1.6 1.5 3.1 2.6 3.1 7.9 0.0 5.6 4.5 8.1 9.9 1.5 1.3 4.1 2.7 8.4 3.3 1.4 DHRSX "DHRS5X, DHRS5Y, DHRSXY, DHRSY, SDR46C1, SDR7C6" ENSG00000169084 "Dehydrogenase/reductase X-linked" Q8N5I4 X 2219506-2502805 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA003035, HPA075955" Approved Uncertain "Mitotic spindle,Cytosol" "Secreted to blood" Yes NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 1: Pancreatic cells - Digestion" Cytosol "Mitotic spindle" "HPA003035: AB_1080631, HPA075955: " "unprognostic (7.77e-2)" "unprognostic (1.06e-1)" "unprognostic (3.95e-2)" "unprognostic (4.65e-3)" "unprognostic (8.87e-2)" "unprognostic (1.78e-1)" "unprognostic (1.29e-1)" "unprognostic (4.59e-3)" "unprognostic (1.08e-1)" "unprognostic (1.21e-1)" "unprognostic (1.08e-2)" "unprognostic (1.17e-1)" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (1.57e-1)" "unprognostic (2.11e-1)" "unprognostic (3.69e-2)" 13.1 16.2 7.0 4.8 8.2 5.2 12.2 6.7 7.7 13.3 11.9 12.7 6.5 13.0 8.0 6.0 11.0 8.8 19.9 6.1 6.8 14.7 30.6 10.3 5.6 11.5 10.1 12.6 21.9 11.5 10.6 8.2 8.4 13.2 8.3 2.2 14.7 7.0 12.4 9.0 10.8 6.9 8.5 10.1 16.5 6.4 10.9 6.1 13.3 7.0 3.9 11.2 9.3 8.2 8.1 35.7 23.9 11.0 28.8 18.0 18.5 17.8 29.9 13.3 17.9 26.9 16.8 12.6 22.6 21.5 31.4 3.9 16.4 14.3 9.4 24.1 26.1 12.2 17.9 21.2 33.8 6.6 9.5 22.3 17.7 11.6 11.4 22.7 10.9 13.9 14.0 6.1 21.7 9.2 28.5 9.7 6.9 10.6 9.9 10.4 12.4 3.5 14.5 19.3 24.3 22.9 17.0 20.3 14.2 14.8 8.7 10.8 15.6 14.5 3.6 8.4 10.6 7.1 0.1 33.2 9.7 8.7 6.7 14.9 38.3 34.6 15.1 30.6 16.0 25.0 13.5 12.7 35.1 20.1 12.3 10.6 56.4 17.7 19.5 28.3 18.2 21.0 7.0 8.2 6.7 7.7 6.1 6.8 11.5 10.1 8.4 8.5 10.9 8.2 8.7 19.2 9.3 64.3 19.2 10.6 22.9 58.0 20.5 9.5 19.3 16.9 23.4 25.8 24.4 25.8 10.4 42.9 17.0 32.9 13.7 52.3 0.6 16.1 15.9 14.8 19.2 13.7 41.2 81.2 43.5 26.9 21.4 14.4 17.8 27.1 15.0 50.6 38.4 3.3 42.7 21.4 32.6 20.8 30.7 3.0 24.2 26.3 12.4 61.8 35.9 9.4 14.4 46.3 31.9 71.0 28.8 25.2 29.1 65.3 49.2 43.7 14.8 6.2 19.7 12.0 18.3 12.0 21.2 11.3 6.5 107.3 14.0 14.6 24.1 29.2 DLGAP3 "DAP3, SAPAP3" ENSG00000116544 "DLG associated protein 3" O95886 1 34865436-34929650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 51.6" "Cell type enhanced" "Detected in many" "Early spermatids: 18.9;Excitatory neurons: 39.1;Horizontal cells: 21.9;Inhibitory neurons: 27.9;Late spermatids: 19.3" "Cancer enhanced" "Detected in some" "testis cancer: 5.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 8.0;NTERA-2: 4.2;SCLC-21H: 12.5;SH-SY5Y: 2.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026445, HPA027304" Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Midbody" Yes NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Endoplasmic reticulum" "Plasma membrane, Midbody" "HPA026445: AB_1847733, HPA027304: " "unprognostic (8.63e-2)" "unprognostic (8.58e-2)" "unprognostic (1.48e-1)" "unprognostic (5.77e-7)" "unprognostic (4.01e-2)" "unprognostic (5.51e-2)" "unprognostic (2.95e-2)" "unprognostic (8.78e-2)" "unprognostic (2.66e-1)" "unprognostic (1.69e-1)" "unprognostic (1.27e-4)" "unprognostic (2.13e-1)" "unprognostic (1.97e-2)" "unprognostic (6.12e-2)" "unprognostic (1.47e-1)" "unprognostic (2.26e-1)" "unprognostic (2.21e-1)" 0.3 0.4 46.9 0.5 41.2 1.1 0.2 0.0 48.2 0.2 0.0 0.3 0.2 0.3 0.0 0.1 0.3 0.1 0.1 36.0 19.1 1.3 0.1 0.2 0.3 0.0 17.8 0.1 1.1 0.2 4.8 0.0 0.0 0.2 0.0 1.8 0.2 0.2 0.1 0.2 0.5 0.0 0.0 1.9 0.3 7.5 51.6 0.3 0.4 0.0 0.1 0.2 0.2 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 8.0 0.1 0.0 1.0 0.0 1.3 0.0 0.0 0.1 0.1 0.6 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.2 0.0 1.3 0.0 0.0 4.2 0.0 0.0 0.4 0.0 0.1 0.0 0.4 12.5 2.4 0.1 0.1 0.0 0.2 0.3 0.0 0.1 0.0 1.3 0.0 0.0 0.1 0.2 1.6 0.1 0.1 0.1 0.1 0.6 0.0 0.0 0.3 0.2 0.0 0.1 0.1 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.2 0.2 46.9 41.2 0.0 48.2 36.0 19.1 0.0 17.8 0.0 0.0 51.6 0.0 0.2 0.0 0.0 1.0 1.8 0.3 0.9 0.8 1.8 4.1 0.7 0.8 1.0 0.0 0.1 1.8 4.2 0.1 0.9 0.8 3.9 0.4 18.9 0.2 0.1 0.4 1.2 0.0 39.1 0.6 0.2 0.4 0.0 0.1 0.0 0.3 0.4 0.1 10.1 21.9 27.9 0.4 0.0 7.1 0.6 19.3 0.9 4.1 0.0 1.9 0.7 1.5 1.0 8.0 0.7 0.2 0.0 0.0 0.8 0.2 1.3 0.8 0.0 2.2 0.0 0.7 0.4 3.4 4.9 1.1 0.3 0.0 1.3 0.1 0.9 0.6 DLGAP5 "DLG1, DLG7, HURP, KIAA0008" ENSG00000126787 "DLG associated protein 5" Q15398 14 55148112-55191608 "Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 29.7;lymphoid tissue: 42.0;testis: 17.4" "Cell type enhanced" "Detected in many" "Erythroid cells: 92.6;Extravillous trophoblasts: 23.1;Plasma cells: 22.1;Spermatocytes: 68.1;Spermatogonia: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 5.4" "Lineage enriched" "Detected in many" 5 "T-cells: 5.4" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA005546 Enhanced Supported "Centriolar satellite,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Centriolar satellite, Cytosol" "HPA005546: AB_1078677" "unprognostic (2.24e-1)" "unprognostic (1.77e-1)" "unprognostic (1.19e-3)" "prognostic unfavorable (4.59e-4)" "unprognostic (1.42e-1)" "unprognostic (1.66e-2)" "prognostic unfavorable (1.52e-6)" "prognostic unfavorable (7.85e-4)" "unprognostic (6.15e-3)" "unprognostic (3.55e-1)" "prognostic unfavorable (9.94e-6)" "unprognostic (4.69e-2)" "unprognostic (0.00e+0)" "unprognostic (1.06e-2)" "unprognostic (3.64e-1)" "unprognostic (1.29e-1)" "unprognostic (1.93e-2)" 0.8 0.3 1.4 8.1 0.9 29.7 1.4 0.4 1.8 0.8 0.6 5.5 5.0 1.3 0.1 5.2 0.4 0.8 0.2 1.0 1.7 0.2 0.7 0.7 17.9 0.7 1.0 0.2 0.1 0.2 0.0 4.1 0.8 0.2 6.7 0.1 0.8 0.1 0.1 3.1 4.6 2.7 0.3 2.6 3.0 17.4 1.1 42.0 0.4 0.0 18.7 2.0 1.5 3.8 144.8 56.8 140.6 63.7 3.3 13.4 43.8 80.3 52.7 115.3 109.3 45.9 75.8 82.1 44.2 46.9 47.4 85.6 91.5 64.0 150.5 101.9 45.7 84.4 49.9 39.3 0.4 82.7 49.3 2.8 2.2 54.8 27.0 18.9 129.0 82.5 70.5 79.8 109.3 69.2 105.0 42.7 72.6 63.3 57.3 80.8 137.9 39.0 37.9 45.2 71.7 40.7 84.8 31.7 30.8 60.6 71.6 31.6 49.6 52.4 133.3 50.6 94.6 19.4 44.9 108.9 35.9 59.6 83.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.9 1.4 0.3 0.0 0.2 0.1 0.2 1.0 0.0 0.0 5.4 0.7 1.4 0.9 0.4 1.8 1.0 1.7 0.7 1.0 0.8 0.3 1.1 3.8 0.1 0.0 0.5 0.0 4.4 1.1 0.7 3.3 0.0 0.0 1.2 0.9 0.4 0.0 1.3 0.0 0.0 11.6 1.4 3.2 0.0 0.4 19.7 7.2 2.6 2.4 0.0 92.6 0.3 0.0 23.1 4.2 7.7 4.5 0.0 15.8 3.9 0.5 10.5 0.0 0.3 3.6 8.2 4.1 1.6 6.0 0.9 3.7 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.2 0.2 1.2 22.1 0.6 0.3 0.1 1.3 0.0 6.6 0.0 3.8 68.1 31.7 11.6 0.4 1.9 4.0 0.9 6.9 1.4 DNHD1 "C11orf47, CCDC35, DHCD1, DKFZp686J0796, DNHD1L, FLJ32752, FLJ35709, FLJ46184" ENSG00000179532 "Dynein heavy chain domain 1" Q96M86 11 6497260-6593758 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 69.5;Erythroid cells: 35.6;Excitatory neurons: 41.4;Inhibitory neurons: 32.8;Oligodendrocyte precursor cells: 36.2;Oligodendrocytes: 67.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039698, HPA040267, HPA057639" Uncertain Approved "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Cytokinetic bridge" "HPA039698: AB_10795111, HPA040267: AB_2676913, HPA057639: AB_2683486" "unprognostic (1.01e-2)" "unprognostic (2.31e-1)" "unprognostic (5.87e-2)" "unprognostic (2.18e-2)" "unprognostic (9.96e-2)" "unprognostic (2.00e-3)" "unprognostic (1.43e-1)" "unprognostic (3.11e-1)" "unprognostic (5.38e-2)" "unprognostic (1.38e-1)" "unprognostic (1.96e-2)" "unprognostic (9.25e-3)" "unprognostic (5.45e-9)" "unprognostic (2.33e-1)" "unprognostic (2.50e-1)" "unprognostic (4.56e-4)" "unprognostic (8.15e-2)" 2.2 1.7 2.6 1.5 3.3 4.5 2.2 2.1 4.3 2.9 2.3 3.3 1.6 2.5 2.1 1.6 2.6 1.4 2.0 2.1 3.2 2.5 2.8 3.3 2.5 4.7 2.8 3.3 1.7 0.4 2.2 0.8 5.0 2.4 1.4 4.0 1.8 1.3 2.0 2.3 3.3 1.4 2.4 2.8 2.0 10.3 3.5 2.1 2.4 0.8 2.0 2.4 2.5 6.2 2.1 2.0 2.4 1.9 2.0 2.9 2.6 1.0 1.2 0.7 0.9 1.3 2.3 2.4 0.4 1.0 1.8 3.7 1.1 1.1 0.9 1.5 2.3 1.8 3.7 1.5 1.3 2.1 0.8 2.0 1.8 2.2 3.6 1.2 0.6 3.1 2.0 2.3 1.0 0.6 0.9 3.0 2.6 0.7 2.0 1.4 0.9 1.5 1.3 1.6 1.1 2.2 0.8 2.2 1.9 1.8 1.3 2.5 1.2 1.3 1.4 1.8 1.4 6.6 5.0 3.0 1.3 2.6 1.7 0.0 0.1 0.5 0.1 0.0 0.2 0.0 0.2 0.1 0.1 0.3 0.3 0.4 0.1 0.0 0.0 0.2 0.2 0.1 2.6 3.3 2.1 4.3 2.1 3.2 4.7 2.8 5.0 2.4 3.5 6.2 2.3 0.0 3.4 69.5 3.8 0.9 1.2 1.9 0.6 9.9 2.7 3.0 3.8 0.0 4.3 0.0 4.2 0.3 4.0 2.2 0.0 0.3 12.7 4.0 1.5 2.8 0.0 35.6 41.4 0.4 0.2 2.2 2.6 3.6 1.3 4.7 3.3 4.8 0.8 10.1 32.8 1.7 0.0 2.5 1.5 13.9 0.9 4.0 0.0 19.7 2.2 3.4 3.1 36.2 67.4 0.4 1.6 1.2 1.7 1.8 2.2 0.6 7.3 9.5 0.0 2.1 1.7 19.5 2.0 1.5 3.8 0.7 2.4 1.8 2.1 1.8 DNMBP "ARHGEF36, KIAA1010, Tuba" ENSG00000107554 "Dynamin binding protein" Q6XZF7 10 99875577-100009947 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 75.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037878, HPA058216" Uncertain Approved "Nucleoli,Nuclear bodies,Golgi apparatus,Cytosol" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" "Nucleoli, Golgi apparatus, Cytosol" "Nuclear bodies" "HPA037878: AB_10675622, HPA058216: AB_2683640" "unprognostic (3.25e-1)" "unprognostic (8.19e-2)" "unprognostic (1.86e-1)" "prognostic favorable (4.95e-6)" "unprognostic (3.92e-2)" "unprognostic (4.13e-1)" "unprognostic (9.79e-2)" "unprognostic (4.07e-1)" "unprognostic (1.90e-1)" "unprognostic (1.02e-1)" "unprognostic (8.67e-3)" "unprognostic (4.03e-2)" "unprognostic (5.07e-3)" "unprognostic (6.52e-2)" "unprognostic (4.95e-2)" "unprognostic (1.28e-1)" "prognostic favorable (6.15e-4)" 13.6 6.0 3.6 5.5 3.7 10.3 10.2 6.2 5.3 15.8 8.6 17.7 22.5 9.6 12.5 10.2 11.3 11.0 7.5 4.7 4.2 20.6 13.1 8.4 4.6 3.7 3.6 11.5 17.6 31.7 3.9 10.5 3.8 8.9 20.7 15.8 8.4 12.8 13.4 27.4 27.2 8.8 3.0 7.7 23.8 6.9 5.2 20.1 8.1 11.1 5.2 19.8 17.7 3.1 25.7 20.7 18.4 29.2 32.9 27.4 4.4 45.2 43.6 21.5 20.7 14.2 38.0 26.6 18.9 34.9 11.8 19.9 21.6 26.1 29.9 1.4 6.7 3.8 23.7 10.0 17.1 2.6 1.8 13.0 5.7 26.6 23.4 75.5 52.1 8.5 3.6 0.0 44.1 3.2 4.5 5.1 17.7 18.0 12.3 5.5 18.7 1.4 36.6 21.9 3.1 4.2 7.4 1.9 5.7 25.3 1.5 2.4 63.4 16.0 15.3 13.1 29.8 2.1 1.7 36.3 15.2 8.4 12.2 0.0 0.8 0.2 0.7 1.2 0.7 1.2 0.1 0.4 0.3 1.9 0.1 0.3 0.7 2.1 1.2 0.3 0.0 0.6 3.6 3.7 6.2 5.3 4.7 4.2 3.7 3.6 3.8 3.0 5.2 3.1 6.8 9.6 11.0 11.1 14.8 35.1 7.2 5.0 5.2 6.3 9.3 6.3 6.1 12.8 11.2 12.9 35.5 7.7 4.4 36.7 3.9 7.5 1.0 27.0 11.0 12.6 3.6 0.0 15.9 14.3 1.4 17.6 26.0 43.9 2.5 4.1 11.4 12.8 4.7 13.5 24.8 25.0 6.1 10.7 9.6 3.2 13.7 20.5 3.6 23.4 3.3 4.3 0.0 10.6 2.6 19.3 23.6 9.1 6.1 4.0 36.5 3.7 19.9 26.6 0.0 4.3 6.9 4.2 9.3 9.0 45.6 3.7 4.3 15.0 28.4 21.8 DNTTIP1 "C20orf167, dJ447F3.4, Tdif1" ENSG00000101457 "Deoxynucleotidyltransferase terminal interacting protein 1" Q9H147 20 45791954-45811427 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 124.8" "Group enriched" "Detected in all" 6 "dendritic cells: 43.3;granulocytes: 124.8;monocytes: 50.9" "Cell line enhanced" "Detected in all" "PC-3: 280.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045496 Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 3: Monocytes - Immune response regulation" "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA045496: " "unprognostic (7.77e-2)" "unprognostic (2.19e-1)" "unprognostic (2.07e-1)" "unprognostic (4.52e-2)" "unprognostic (2.50e-1)" "unprognostic (3.05e-2)" "prognostic unfavorable (1.79e-5)" "unprognostic (6.29e-2)" "unprognostic (7.16e-2)" "unprognostic (1.85e-1)" "unprognostic (5.81e-3)" "unprognostic (5.63e-2)" "prognostic unfavorable (1.90e-6)" "unprognostic (3.18e-1)" "unprognostic (1.54e-1)" "unprognostic (1.19e-1)" "unprognostic (1.30e-1)" 19.9 19.4 22.8 24.7 23.2 44.1 20.0 23.3 26.1 21.0 23.9 33.2 17.5 27.2 25.0 19.5 24.7 21.7 27.3 23.1 24.2 19.2 19.3 22.3 23.7 23.2 24.3 20.6 15.8 26.1 20.8 23.1 23.4 22.0 38.7 21.7 19.4 22.8 62.0 28.2 21.0 24.4 23.4 25.3 24.6 30.4 23.8 30.1 19.6 31.0 28.0 34.0 19.3 24.4 79.8 41.6 42.1 40.2 31.7 34.1 43.7 29.2 47.1 92.7 83.4 134.8 126.1 32.8 93.2 42.9 147.1 58.4 37.3 62.8 61.1 18.0 47.2 36.0 45.2 87.2 64.4 70.0 56.7 34.4 58.0 60.8 58.2 42.4 55.1 46.9 33.9 32.6 56.0 107.5 57.9 108.2 28.7 44.8 280.7 46.0 52.3 34.4 47.4 37.9 39.5 35.6 59.7 48.2 65.2 32.7 47.6 111.4 32.6 55.4 41.1 54.0 71.0 35.5 24.8 41.0 120.5 44.8 48.1 16.7 50.9 71.0 4.1 22.0 4.2 12.0 5.5 7.0 43.3 11.1 10.1 4.7 124.8 3.3 13.6 16.6 9.3 13.5 22.8 23.2 23.3 26.1 23.1 24.2 23.2 24.3 23.4 23.4 23.8 24.4 21.2 16.0 22.9 10.1 22.0 25.5 44.8 43.1 22.2 19.8 20.3 23.0 19.9 21.5 37.1 25.8 4.2 60.7 14.3 37.2 50.9 57.6 37.9 35.1 19.4 22.6 22.2 9.7 11.2 75.4 43.0 25.7 26.5 20.6 6.3 26.4 25.0 16.6 70.8 20.2 9.5 92.7 59.0 26.3 34.7 15.7 28.3 32.4 16.0 11.2 68.3 53.1 15.5 7.5 10.6 105.0 50.5 27.1 21.9 38.2 33.3 44.2 48.0 29.7 0.0 20.8 26.5 92.9 35.4 19.4 27.6 57.7 16.3 32.9 34.8 60.7 DNTTIP2 "ERBP, HSU15552, TdIF2" ENSG00000067334 "Deoxynucleotidyltransferase terminal interacting protein 2" Q5QJE6 1 93866284-93879918 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044502, HPA053707" Supported Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 31: Non-specific - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Nucleoli rim, Mitotic chromosome" "HPA044502: AB_10960277, HPA053707: AB_2682236" "unprognostic (2.95e-3)" "unprognostic (3.84e-2)" "unprognostic (6.21e-3)" "unprognostic (1.12e-2)" "unprognostic (2.41e-1)" "unprognostic (8.92e-2)" "prognostic unfavorable (1.90e-6)" "unprognostic (7.94e-2)" "unprognostic (5.57e-3)" "unprognostic (2.69e-2)" "unprognostic (2.02e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.80e-5)" "unprognostic (2.59e-1)" "unprognostic (8.41e-2)" "unprognostic (2.25e-1)" "unprognostic (1.06e-2)" 5.0 3.7 4.9 3.5 5.2 15.3 5.0 10.3 6.7 3.5 5.6 3.4 2.7 4.0 6.3 4.4 3.5 4.5 4.5 5.5 5.4 4.2 5.0 3.7 5.5 4.8 4.9 4.3 3.4 3.8 2.1 4.6 5.1 3.7 3.6 4.2 2.9 3.0 8.9 5.5 2.7 3.7 3.8 4.5 3.6 4.5 5.3 4.3 4.7 5.0 5.2 6.5 2.8 6.8 14.3 6.6 7.2 7.8 6.9 6.2 11.1 9.4 6.6 11.0 9.4 7.3 6.1 18.8 12.2 9.9 13.8 7.7 11.9 11.2 15.6 11.4 6.6 15.4 11.3 11.0 7.2 17.4 5.3 6.8 11.9 11.9 9.8 5.5 7.9 6.0 18.6 6.0 15.1 6.3 12.2 11.3 14.2 6.3 10.6 7.0 15.6 7.2 11.3 10.8 8.7 7.7 9.8 14.4 10.5 9.2 6.2 12.6 7.7 8.8 9.2 10.2 15.9 6.4 9.3 15.3 5.1 13.6 5.9 9.7 5.7 11.6 6.4 8.3 7.7 8.2 5.8 5.8 5.1 8.4 5.3 6.9 8.0 9.6 8.5 3.5 6.4 6.8 4.9 5.2 10.3 6.7 5.5 5.4 4.8 4.9 5.1 3.8 5.3 6.8 98.9 57.7 78.2 3.6 66.7 54.4 163.0 57.9 43.3 33.9 27.5 38.9 73.0 11.5 91.2 12.9 58.4 52.0 110.2 17.3 21.5 74.3 53.8 85.1 72.0 74.2 8.4 20.6 6.8 60.3 44.4 54.3 38.2 122.4 119.4 36.6 25.7 19.4 38.1 20.2 7.7 14.5 46.8 29.5 72.1 11.0 25.7 75.8 23.2 8.4 52.1 29.2 48.4 3.5 7.2 88.6 20.1 25.9 50.1 96.7 17.2 19.6 85.1 34.4 19.7 90.7 79.0 62.8 65.9 40.0 50.6 55.8 87.7 44.4 23.1 112.0 DOK3 FLJ22570 ENSG00000146094 "Docking protein 3" Q7L591 5 177501904-177511274 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 93.6;lymphoid tissue: 118.4" "Group enriched" "Detected in many" 5 "B-cells: 31.6;granulocytes: 18.3;Hofbauer cells: 55.7;Kupffer cells: 51.1;Macrophages: 38.3;monocytes: 45.4;Plasma cells: 38.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 133.6" "Group enriched" "Detected in many" 6 "B-cells: 37.2;granulocytes: 133.6;monocytes: 77.6" "Cell line enhanced" "Detected in many" "Daudi: 124.0;HMC-1: 87.5;REH: 148.6;U-698: 122.1;U-937: 88.0" "Low region specificity" "Detected in many" HPA077312 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" Yes NA 240000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Nucleoplasm, Cytokinetic bridge, Cytosol" "HPA077312: AB_2732339" "unprognostic (2.21e-2)" "unprognostic (1.14e-2)" "unprognostic (2.05e-2)" "unprognostic (5.74e-3)" "unprognostic (2.32e-2)" "unprognostic (1.34e-3)" "unprognostic (4.17e-2)" "unprognostic (2.20e-1)" "unprognostic (8.00e-2)" "unprognostic (1.32e-1)" "unprognostic (1.21e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (3.82e-11)" "unprognostic (1.34e-1)" "unprognostic (7.25e-2)" "unprognostic (1.55e-1)" "unprognostic (3.78e-2)" 11.0 6.1 5.2 30.2 6.2 93.6 4.4 6.5 7.9 3.2 6.3 8.2 6.5 3.4 1.7 5.5 7.8 4.3 4.1 6.0 7.0 5.0 6.5 27.1 31.5 11.3 6.8 2.1 4.5 0.8 3.4 7.0 10.5 5.5 3.5 2.1 6.6 2.0 3.6 2.6 28.9 4.5 6.7 118.4 5.9 8.9 9.9 4.3 4.4 4.1 32.3 7.1 4.0 8.1 5.2 7.8 5.4 6.3 3.2 0.4 13.0 4.4 1.1 14.0 12.9 11.0 2.2 124.0 3.2 4.0 6.8 8.9 12.2 7.6 6.9 26.1 14.6 21.3 21.4 2.5 1.0 46.1 87.5 1.6 4.5 16.2 1.6 1.5 1.9 11.4 14.8 50.2 5.1 12.9 2.7 52.5 12.2 1.5 12.9 148.6 9.3 1.2 4.4 5.2 7.4 4.9 2.0 2.1 6.2 4.8 11.7 63.4 2.7 12.3 11.3 6.5 5.4 11.1 15.0 122.1 2.7 88.0 2.2 16.8 62.4 57.0 0.3 61.3 0.6 37.2 0.1 0.3 14.5 19.6 0.1 0.1 133.6 0.5 77.6 1.2 0.0 28.7 5.2 6.2 6.5 7.9 6.0 7.0 11.3 6.8 10.5 6.7 9.9 8.1 1.4 0.0 5.6 1.6 31.6 0.3 0.1 0.4 1.8 0.8 1.0 0.9 0.4 0.0 0.2 0.0 0.0 0.5 0.3 0.2 0.0 0.2 0.0 0.4 0.4 1.9 0.0 6.3 4.1 0.2 0.7 1.2 0.5 0.8 18.3 0.2 7.1 0.8 55.7 0.0 3.5 0.3 0.0 51.1 2.3 0.4 0.6 38.3 1.8 3.7 45.4 0.3 2.1 0.5 0.5 0.0 0.7 1.2 38.3 0.2 0.2 0.1 0.1 0.6 0.0 1.8 0.4 3.0 1.9 0.7 0.3 1.0 2.2 0.3 0.8 0.1 DOP1B "C21orf5, DOPEY2, KIAA0933" ENSG00000142197 "DOP1 leucine zipper like protein B" Q9Y3R5 21 36156782-36294274 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 5.2;dendritic cells: 3.8;Extravillous trophoblasts: 11.4;Hofbauer cells: 16.7;Syncytiotrophoblasts: 8.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 19.8" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072065 Enhanced Approved Nucleoplasm,Mitochondria Yes No "Cluster 19: B-cells - Humoral immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Mitochondria "HPA072065: AB_2686486" "prognostic unfavorable (7.08e-4)" "unprognostic (7.68e-2)" "unprognostic (2.50e-2)" "unprognostic (1.99e-1)" "unprognostic (1.84e-1)" "unprognostic (1.66e-2)" "unprognostic (1.04e-2)" "unprognostic (1.01e-1)" "unprognostic (2.38e-1)" "unprognostic (1.36e-1)" "unprognostic (3.13e-2)" "unprognostic (4.35e-2)" "unprognostic (3.01e-2)" "unprognostic (2.59e-2)" "unprognostic (1.39e-1)" "unprognostic (1.06e-1)" "unprognostic (2.85e-1)" 3.5 1.7 2.9 5.6 4.8 24.2 5.8 19.8 8.0 4.6 0.0 15.4 12.6 2.3 3.0 11.8 4.2 4.1 4.5 3.6 1.0 3.2 9.1 4.9 4.7 3.6 1.1 1.6 4.6 30.4 2.3 3.1 4.5 12.1 15.1 1.6 19.3 3.4 15.9 7.1 11.7 3.8 0.1 5.5 20.5 3.5 2.1 6.5 4.0 13.5 6.3 4.0 5.9 3.4 25.9 5.4 4.0 6.8 4.4 8.4 38.2 12.0 14.2 16.7 10.4 3.8 2.0 4.8 1.8 9.0 12.7 5.2 7.8 2.8 13.5 8.8 7.0 11.0 1.2 1.4 3.9 10.8 5.5 2.9 5.5 10.9 2.9 10.0 7.1 11.2 3.5 7.6 5.0 29.0 8.7 11.1 3.3 30.4 5.6 15.4 2.3 23.7 8.8 10.2 10.7 6.1 8.0 35.9 10.1 5.5 13.1 13.2 12.2 6.4 1.7 8.4 9.8 5.7 15.0 2.2 9.2 23.0 3.7 1.0 3.0 6.1 2.6 2.7 1.4 7.3 1.7 1.5 1.9 10.5 1.1 0.9 4.8 1.0 2.4 5.9 1.4 1.4 2.9 4.8 19.8 8.0 3.6 1.0 3.6 1.1 4.5 0.1 2.1 3.4 2.8 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 1.9 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 11.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 8.1 0.6 0.0 0.0 0.0 DPH2 DPH2L2 ENSG00000132768 "Diphthamide biosynthesis 2" Q9BQC3 1 43970000-43973369 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045796 Uncertain Approved Nucleoplasm Yes No "Cluster 22: NK-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 16: U-266 - Nucleosome" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA045796: AB_2679456" "unprognostic (2.41e-1)" "unprognostic (1.15e-1)" "unprognostic (4.20e-3)" "unprognostic (9.13e-3)" "unprognostic (3.83e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (1.17e-8)" "unprognostic (1.38e-1)" "unprognostic (1.81e-1)" "unprognostic (3.72e-1)" "unprognostic (2.49e-1)" "unprognostic (3.42e-3)" "unprognostic (2.60e-1)" "prognostic favorable (1.37e-4)" "unprognostic (1.38e-1)" "unprognostic (2.41e-2)" "unprognostic (6.37e-2)" 8.2 11.5 9.3 10.8 9.6 7.0 7.9 9.0 10.2 7.2 9.0 9.7 7.3 7.7 6.1 11.8 8.2 5.5 11.6 9.1 8.5 13.2 12.6 7.1 12.4 8.7 9.2 7.2 15.9 10.2 8.8 6.6 9.0 8.1 9.2 3.5 9.5 6.7 32.8 10.5 9.0 8.9 8.6 11.8 9.7 7.2 9.4 8.8 7.4 17.0 10.9 12.3 6.7 9.5 25.0 28.5 12.2 26.8 9.2 9.6 41.6 13.0 13.9 32.9 26.9 36.1 23.8 41.4 21.4 13.3 17.0 28.1 41.7 36.8 18.4 28.0 36.1 42.4 36.1 37.9 24.1 49.9 23.4 14.9 40.6 39.2 21.0 10.0 23.2 32.0 55.4 23.1 16.8 28.6 44.6 28.3 86.3 40.5 31.4 37.6 28.2 67.4 20.6 19.5 42.8 49.3 17.2 43.1 32.6 16.3 18.2 34.3 15.4 16.1 36.7 28.6 52.4 55.3 98.7 43.0 14.2 55.0 24.1 0.0 6.6 0.4 6.1 9.4 9.0 8.3 6.4 6.5 10.1 8.8 6.4 9.3 0.6 10.3 4.8 8.4 6.6 6.3 9.3 9.6 9.0 10.2 9.1 8.5 8.7 9.2 9.0 8.6 9.4 9.5 5.8 0.0 4.8 5.2 14.4 22.9 13.2 8.9 8.6 6.8 10.3 10.0 9.3 7.2 5.2 1.8 10.4 14.8 8.8 4.8 5.9 16.5 0.3 4.0 5.6 7.6 12.0 6.3 6.9 18.8 16.2 6.2 8.6 4.3 4.5 6.9 2.5 5.7 8.6 3.3 6.5 8.1 4.1 3.7 7.1 1.0 8.4 4.4 5.4 0.0 9.2 4.4 12.3 4.0 6.9 15.2 3.0 3.8 11.5 23.6 3.8 9.0 6.0 6.0 0.0 6.5 8.0 9.4 24.9 10.3 27.1 8.6 6.9 12.7 13.7 9.0 DPH7 "C9orf112, FLJ90634, RRT2, WDR85" ENSG00000148399 "Diphthamide biosynthesis 7" Q9BTV6 9 137554444-137578925 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 189.9;Spermatogonia: 100.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022911 Uncertain Approved "Nuclear bodies" Yes No "Cluster 46: Basophils - DNA binding" "Cluster 50: Non-specific - Ribosome" "Cluster 21: OE19 - Mitochondria" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nuclear bodies" "HPA022911: AB_1858823" "unprognostic (1.43e-1)" "unprognostic (4.81e-2)" "unprognostic (3.41e-2)" "unprognostic (2.25e-2)" "unprognostic (1.19e-1)" "unprognostic (6.60e-3)" "unprognostic (1.48e-2)" "unprognostic (1.78e-1)" "unprognostic (2.14e-2)" "unprognostic (9.48e-2)" "prognostic favorable (6.52e-4)" "unprognostic (2.10e-2)" "prognostic unfavorable (1.52e-5)" "unprognostic (2.30e-3)" "unprognostic (3.06e-2)" "unprognostic (2.15e-1)" "prognostic favorable (3.23e-4)" 8.2 12.3 3.4 2.6 3.6 4.2 9.5 4.5 4.1 15.7 3.9 13.8 2.2 12.6 7.0 9.0 14.6 2.6 9.4 3.6 3.3 10.2 10.9 9.4 4.7 3.7 3.3 12.8 20.3 6.3 13.5 3.4 4.0 15.0 4.1 2.8 9.9 5.4 8.3 11.0 12.2 4.8 3.3 15.2 12.3 9.3 3.8 5.6 12.8 2.4 5.3 11.2 11.1 5.7 4.5 5.2 8.2 7.6 6.2 5.1 10.2 5.1 5.2 9.1 7.7 11.0 5.4 10.6 9.3 5.9 4.8 9.8 10.6 10.1 8.3 9.2 13.2 4.9 6.6 3.7 7.0 10.6 9.5 5.4 7.6 5.1 9.2 6.5 14.4 7.1 9.2 5.7 7.2 15.3 8.2 9.9 10.4 19.9 13.3 13.7 3.7 7.6 6.9 4.5 10.8 7.3 8.7 7.0 5.4 5.7 7.9 9.1 6.5 6.2 5.4 7.7 9.5 3.7 9.1 12.5 3.9 6.1 6.3 9.5 5.1 6.2 4.5 4.8 6.3 5.6 7.2 6.4 5.9 4.7 5.1 4.9 1.6 4.5 4.0 8.0 5.4 4.6 3.4 3.6 4.5 4.1 3.6 3.3 3.7 3.3 4.0 3.3 3.8 5.7 21.0 6.4 11.9 21.2 17.7 16.7 9.8 18.9 8.0 18.7 14.7 20.6 15.5 2.8 11.5 1.8 50.1 22.1 22.5 7.7 3.9 10.6 3.0 11.1 17.1 13.8 6.7 5.5 17.2 9.2 14.9 14.5 13.3 10.2 10.8 26.5 8.2 6.5 11.9 16.8 21.5 11.7 6.1 6.6 7.2 7.5 16.4 8.8 8.8 15.0 9.9 15.4 23.7 16.1 28.2 11.5 10.3 15.8 24.7 18.6 7.2 5.2 14.2 58.8 19.7 13.1 16.0 189.9 100.0 11.4 18.9 12.2 18.0 19.9 15.0 11.1 DPPA4 FLJ10713 ENSG00000121570 "Developmental pluripotency associated 4" Q7L190 3 109326141-109337572 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.7;lymphoid tissue: 12.2;testis: 4.1" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 22.3;Erythroid cells: 16.4;Extravillous trophoblasts: 17.2;Spermatogonia: 11.7;Syncytiotrophoblasts: 6.2" "Cancer enriched" "Detected in single" 218 "testis cancer: 59.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "plasmacytoid DC: 7.3" "Lineage enriched" "Detected in single" 12 "dendritic cells: 7.3" "Group enriched" "Detected in some" 4 "HAP1: 89.7;NTERA-2: 327.5;SuSa: 120.7" "Not detected" "Not detected" "Not detected" "Not detected" "CAB020678, HPA035249, HPA035250" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome,Cytosol" Yes NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 5: NTERA-2 - Transcription" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome, Cytosol" "CAB020678: , HPA035249: AB_2674535, HPA035250: AB_2674536" "unprognostic (2.07e-2)" "unprognostic (2.53e-2)" "unprognostic (3.80e-1)" "unprognostic (2.53e-1)" "unprognostic (8.57e-2)" "unprognostic (1.80e-2)" "unprognostic (1.67e-1)" "unprognostic (1.52e-1)" "unprognostic (9.83e-2)" "unprognostic (2.02e-2)" "unprognostic (6.60e-2)" "unprognostic (2.48e-2)" "unprognostic (3.03e-8)" "unprognostic (5.28e-2)" "unprognostic (5.04e-2)" "unprognostic (5.56e-2)" "unprognostic (3.85e-2)" 0.0 0.0 0.0 0.1 0.0 4.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.7 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.1 0.0 12.2 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 43.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 89.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 327.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 120.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.1 0.0 0.5 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 22.3 4.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 16.4 0.1 0.0 17.2 0.5 0.0 0.0 1.3 0.0 0.4 1.6 1.7 0.0 0.1 0.0 0.0 0.3 0.0 0.6 0.3 0.4 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 0.7 0.0 0.0 0.9 0.3 0.3 11.7 0.0 0.0 6.2 0.5 0.2 0.0 0.3 DPY19L2 "FLJ32949, SPATA34" ENSG00000177990 "Dpy-19 like 2" Q6NUT2 12 63558913-63668939 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 65.6" "Group enriched" "Detected in many" 4 "Early spermatids: 329.9;Excitatory neurons: 124.1;Inhibitory neurons: 137.2;Late spermatids: 363.0;Oligodendrocyte precursor cells: 124.1;Spermatocytes: 143.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-266/84: 9.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA071264, HPA078305" Enhanced Approved Nucleoplasm,Mitochondria Yes No "Cluster 16: MAIT-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Mitochondria Nucleoplasm "HPA071264: AB_2686375, HPA078305: " "unprognostic (1.97e-1)" "unprognostic (4.08e-1)" "unprognostic (4.46e-3)" "unprognostic (2.50e-2)" "unprognostic (1.64e-1)" "unprognostic (1.17e-4)" "unprognostic (2.28e-2)" "unprognostic (2.14e-3)" "unprognostic (1.53e-1)" "unprognostic (3.64e-1)" "unprognostic (3.99e-3)" "unprognostic (1.97e-1)" "unprognostic (6.31e-3)" "unprognostic (4.22e-3)" "unprognostic (5.88e-2)" "unprognostic (8.90e-3)" "unprognostic (1.79e-1)" 6.7 5.3 4.0 0.5 3.9 3.0 4.7 7.0 6.9 11.4 6.6 5.2 0.6 7.8 4.1 1.4 6.4 2.8 19.2 3.0 4.3 12.7 0.2 1.3 0.9 2.4 3.0 11.0 2.7 9.0 10.5 1.2 1.5 9.3 1.3 14.4 1.6 4.7 0.5 1.6 1.7 3.5 0.8 1.7 2.9 65.6 3.3 0.7 13.1 0.6 0.6 6.3 5.1 4.2 1.0 2.6 2.2 5.4 0.6 0.0 0.2 1.8 1.8 2.4 3.1 0.4 0.8 2.8 1.8 0.7 2.9 0.4 2.7 0.3 3.6 1.5 1.7 4.6 1.4 1.7 0.5 3.4 1.4 1.5 0.1 1.1 0.0 6.1 0.8 2.2 1.9 2.9 3.9 1.7 0.2 1.4 2.1 0.4 2.4 0.0 1.8 0.0 4.6 0.5 7.0 0.7 0.6 0.2 1.0 0.9 1.9 0.9 0.5 3.2 4.2 0.5 4.6 7.5 9.3 0.0 3.4 1.6 3.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.1 4.0 3.9 7.0 6.9 3.0 4.3 2.4 3.0 1.5 0.8 3.3 4.2 6.7 3.2 0.0 23.2 0.2 0.5 2.9 0.1 2.2 49.6 1.9 1.8 32.3 1.5 3.8 12.9 14.6 2.0 0.3 0.1 5.9 0.4 329.9 5.6 7.1 1.7 0.0 7.2 124.1 0.0 1.3 2.2 0.5 2.1 2.5 1.2 1.4 0.1 0.3 3.3 137.2 0.1 6.1 0.0 0.4 363.0 7.2 0.4 7.2 11.2 0.1 9.2 0.0 124.1 5.0 0.2 0.0 8.6 0.5 2.9 0.0 6.4 11.6 6.7 26.3 3.8 19.9 143.3 4.9 0.2 0.4 1.4 0.8 3.6 0.1 1.1 DSN1 "C20orf172, dJ469A13.2, hKNL-3, KNL3, MIS13" ENSG00000149636 "DSN1 component of MIS12 kinetochore complex" Q9H410 20 36751791-36773818 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 49.8;Spermatocytes: 115.5;Spermatogonia: 75.1;Syncytiotrophoblasts: 47.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002813, HPA030627" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies,Kinetochore,Cytosol" Yes Yes "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli fibrillar center, Nuclear bodies, Kinetochore, Cytosol" "HPA002813: AB_1078343, HPA030627: AB_2732460" "unprognostic (3.60e-2)" "prognostic favorable (4.49e-4)" "unprognostic (5.22e-3)" "unprognostic (1.13e-3)" "unprognostic (2.00e-1)" "unprognostic (4.64e-2)" "prognostic unfavorable (4.16e-5)" "unprognostic (3.93e-1)" "unprognostic (9.35e-2)" "unprognostic (5.51e-2)" "unprognostic (2.98e-2)" "unprognostic (7.66e-2)" "prognostic unfavorable (1.54e-5)" "unprognostic (6.92e-2)" "unprognostic (2.53e-1)" "unprognostic (2.58e-2)" "unprognostic (2.84e-1)" 5.9 9.9 4.2 7.5 4.2 14.3 8.6 3.9 4.5 5.0 5.2 9.2 6.8 4.4 9.3 7.9 4.1 4.4 5.1 4.3 4.4 4.8 9.1 6.3 12.8 4.0 3.9 4.3 4.3 5.5 3.5 8.8 4.1 6.5 10.8 10.7 5.9 6.3 4.0 8.0 7.8 6.3 3.9 9.6 7.3 23.3 4.1 16.4 5.1 4.8 14.3 4.4 4.7 4.7 36.7 29.1 35.7 29.5 14.0 18.0 24.7 42.9 35.1 63.9 70.2 52.5 44.4 39.3 27.4 23.0 69.1 45.8 33.3 32.7 60.3 18.2 22.7 78.3 26.2 36.1 3.0 46.2 34.0 7.0 9.4 43.7 13.8 10.4 31.5 42.4 30.9 33.7 41.7 25.3 59.2 34.5 16.8 63.3 55.1 46.1 109.4 28.4 16.2 20.5 37.8 16.9 52.9 53.7 25.8 26.3 55.9 30.5 16.4 60.1 35.0 56.9 46.1 27.3 39.1 46.4 49.8 40.8 42.6 53.4 6.4 14.5 7.4 11.0 8.4 14.6 8.1 10.3 7.1 18.4 10.1 9.0 11.9 11.1 10.1 46.9 12.2 6.7 4.2 4.2 3.9 4.5 4.3 4.4 4.0 3.9 4.1 3.9 4.1 4.7 6.5 6.4 4.4 1.6 10.3 5.0 11.4 7.6 3.4 8.0 8.7 7.6 5.4 2.8 8.6 5.5 29.2 49.8 9.8 9.2 7.9 6.8 10.6 5.5 5.9 8.1 2.4 22.1 6.3 6.4 30.4 8.4 20.9 9.4 3.8 21.8 7.9 6.2 14.7 6.7 4.4 13.6 4.1 6.3 4.6 8.0 8.7 6.7 1.8 5.6 7.4 6.0 7.2 3.0 3.6 5.1 5.4 7.5 22.9 7.1 7.7 3.6 8.2 17.5 0.0 5.3 8.2 115.5 75.1 12.3 7.2 47.5 7.7 6.9 13.6 11.0 DTL "CDT2, DCAF2, L2DTL, RAMP" ENSG00000143476 "Denticleless E3 ubiquitin protein ligase homolog" Q9NZJ0 1 212035553-212107400 "Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA replication, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 14.6;intestine: 4.7;lymphoid tissue: 14.2;placenta: 3.9;testis: 13.7" "Cell type enhanced" "Detected in many" "Early spermatids: 25.3;Erythroid cells: 36.2;Extravillous trophoblasts: 16.2;Spermatocytes: 53.2;Spermatogonia: 20.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 2.0" "Lineage enriched" "Detected in single" 8 "T-cells: 2.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028016, HPA032023, HPA032031" Supported Supported Nucleoplasm,Nucleoli,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli, Cytosol" "HPA028016: AB_10611958, HPA032023: AB_2674114, HPA032031: AB_2674119" "unprognostic (7.61e-2)" "unprognostic (1.01e-3)" "unprognostic (2.14e-2)" "unprognostic (3.05e-2)" "unprognostic (2.19e-1)" "unprognostic (5.31e-2)" "prognostic unfavorable (4.41e-5)" "unprognostic (8.96e-3)" "unprognostic (2.45e-3)" "unprognostic (8.83e-3)" "unprognostic (2.52e-3)" "unprognostic (2.83e-2)" "prognostic unfavorable (1.71e-9)" "unprognostic (5.93e-2)" "unprognostic (2.01e-1)" "unprognostic (1.96e-2)" "unprognostic (2.82e-1)" 0.6 0.2 0.0 4.1 0.0 14.6 1.9 0.0 0.1 0.6 0.0 3.3 2.3 1.1 0.1 1.9 0.4 0.4 0.1 0.0 0.0 0.1 1.2 1.4 5.6 0.0 0.1 0.1 0.1 0.5 0.2 3.9 0.0 0.4 4.7 0.0 0.4 0.1 0.1 2.1 3.0 1.9 0.0 2.5 1.3 13.7 0.1 14.2 0.5 0.0 6.4 1.2 0.7 0.0 34.1 28.1 48.0 23.6 2.9 5.8 23.3 41.3 25.5 38.1 56.1 17.6 29.0 25.2 15.4 16.1 25.0 25.8 62.5 34.9 54.7 31.4 30.9 40.7 33.6 21.5 0.1 54.1 25.3 2.5 1.2 62.2 32.4 6.8 17.7 44.7 49.1 51.1 44.4 13.5 75.3 24.3 56.6 25.2 32.9 57.2 84.0 49.2 11.6 22.9 29.6 46.0 39.2 37.5 17.6 47.7 32.0 24.1 9.7 38.2 28.6 40.5 47.8 18.4 30.5 57.7 19.1 35.5 37.8 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.3 0.5 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 2.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 2.3 2.3 0.4 1.7 0.0 0.0 1.3 1.3 7.0 1.5 0.9 0.0 0.0 12.8 1.4 1.5 0.0 0.4 25.3 0.4 1.3 5.2 0.0 36.2 0.2 0.0 16.2 2.4 3.1 1.0 0.0 11.4 0.7 0.4 4.7 0.0 0.3 3.3 0.0 0.3 0.8 12.4 1.2 2.2 0.0 1.0 0.2 0.0 0.0 0.0 0.1 0.6 0.4 0.0 12.8 0.2 0.6 0.0 0.1 0.0 0.0 0.2 2.7 53.2 20.8 5.6 1.7 1.5 2.6 1.6 5.2 0.7 DTNBP1 "BLOC1S8, DBND, Dysbindin, HPS7, My031" ENSG00000047579 "Dystrobrevin binding protein 1" Q96EV8 6 15522807-15663058 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction" "Albinism, Hermansky-Pudlak syndrome, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 127.0" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 173.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028053, HPA029615, HPA029616" Approved Enhanced Microtubules,Midbody Yes No "Cluster 48: NK-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 46: Photoreceptor cells - Phototransduction" Microtubules Midbody "HPA028053: AB_10599296, HPA029615: AB_10599945, HPA029616: AB_10602413" "unprognostic (2.83e-1)" "prognostic favorable (2.82e-4)" "unprognostic (1.62e-1)" "unprognostic (1.20e-1)" "unprognostic (4.93e-2)" "unprognostic (1.29e-2)" "prognostic unfavorable (8.72e-4)" "prognostic favorable (6.34e-5)" "unprognostic (1.36e-1)" "unprognostic (4.28e-3)" "unprognostic (2.21e-3)" "unprognostic (2.08e-1)" "unprognostic (1.88e-2)" "unprognostic (1.37e-1)" "unprognostic (1.75e-1)" "unprognostic (8.81e-3)" "unprognostic (1.09e-2)" 16.2 9.3 40.8 17.6 60.1 16.7 14.8 35.1 46.6 13.2 32.5 26.0 11.8 13.5 18.3 11.3 11.6 12.6 21.5 42.8 45.7 18.0 8.6 14.7 29.3 40.2 41.9 11.0 11.9 21.0 11.5 14.9 40.8 13.8 16.4 127.0 13.7 14.8 26.8 13.6 17.4 17.8 38.0 22.1 17.1 12.0 44.3 21.4 13.2 16.0 30.9 19.8 12.5 37.8 30.6 12.9 10.9 23.7 15.5 17.8 16.6 15.3 20.0 36.0 32.4 17.6 13.7 42.9 40.5 21.8 29.6 10.4 21.8 16.3 32.6 27.3 28.9 30.2 15.4 25.7 27.3 30.6 24.8 16.9 24.7 18.5 26.8 16.6 32.2 29.0 29.3 10.2 22.1 35.9 31.9 48.7 7.7 25.4 18.6 37.7 21.2 33.4 33.7 31.7 22.1 9.5 12.1 28.4 36.4 25.1 20.6 19.4 15.2 20.5 13.4 21.2 28.6 27.7 57.3 30.9 9.5 27.1 39.5 11.1 10.1 14.4 19.5 12.4 13.1 24.8 16.5 17.2 11.0 31.3 15.5 12.6 11.6 49.3 9.0 30.8 12.1 11.5 40.8 60.1 35.1 46.6 42.8 45.7 40.2 41.9 40.8 38.0 44.3 37.8 23.2 12.8 11.3 35.3 42.6 29.1 16.5 12.5 11.4 47.2 14.3 13.1 29.3 15.7 11.4 14.7 58.4 41.4 29.6 18.6 37.2 37.5 50.5 16.3 9.8 31.7 13.8 5.5 36.3 35.8 17.9 16.9 14.3 14.5 54.6 54.1 20.0 6.0 54.8 25.2 38.6 17.5 8.2 18.5 32.4 26.6 10.2 22.1 37.4 39.4 29.8 55.2 64.9 26.7 36.3 26.5 12.1 15.4 20.2 12.9 27.2 81.6 13.0 173.4 6.6 12.3 20.8 22.3 18.3 8.6 22.0 16.7 29.1 11.0 19.2 12.0 DTWD1 "MDS009, MGC111207" ENSG00000104047 "DTW domain containing 1" Q8N5C7 15 49621037-49656232 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042214 Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome,Vesicles" Yes No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoli rim" "Nucleoplasm, Mitotic chromosome, Vesicles" "HPA042214: AB_2677903" "unprognostic (2.60e-2)" "unprognostic (1.73e-1)" "unprognostic (3.00e-1)" "unprognostic (3.70e-4)" "unprognostic (8.12e-2)" "unprognostic (2.37e-1)" "unprognostic (1.82e-1)" "unprognostic (9.87e-2)" "unprognostic (4.44e-3)" "unprognostic (4.25e-2)" "unprognostic (5.42e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-3)" "unprognostic (1.02e-1)" "unprognostic (7.85e-2)" "unprognostic (2.80e-2)" "unprognostic (2.35e-1)" 19.6 11.8 7.7 13.0 10.1 5.4 18.2 8.2 9.1 27.4 6.5 21.1 7.4 22.6 16.8 13.3 21.1 23.0 11.0 9.0 8.9 11.0 11.5 10.9 12.9 5.7 6.9 22.7 33.3 11.5 9.2 12.8 6.0 15.7 11.9 8.8 21.5 14.7 10.3 12.2 9.1 20.5 6.4 9.0 14.9 9.5 9.9 11.7 17.6 21.1 10.0 20.4 15.9 9.8 10.0 11.9 21.2 11.5 41.3 84.1 16.6 29.3 28.6 36.8 27.5 4.2 8.3 16.7 20.3 38.7 16.8 17.8 15.6 15.8 37.7 10.8 11.2 13.8 23.5 14.5 29.1 18.0 11.1 38.8 20.4 24.3 29.7 32.9 15.5 19.3 26.3 17.3 41.7 23.3 12.3 15.1 12.4 22.6 15.7 17.4 44.7 64.9 12.3 7.1 18.6 14.4 34.7 11.5 27.3 22.1 12.1 25.4 10.7 43.6 17.3 25.6 32.3 13.2 22.2 10.0 37.5 53.9 28.3 8.7 9.7 5.2 6.8 11.7 9.8 9.7 10.3 11.6 12.8 10.1 12.0 11.5 2.6 13.9 15.3 25.3 8.9 6.0 7.7 10.1 8.2 9.1 9.0 8.9 5.7 6.9 6.0 6.4 9.9 9.8 39.9 19.2 15.0 36.6 16.6 19.2 15.4 31.9 18.2 41.8 23.0 34.0 18.8 12.8 22.1 35.0 31.3 23.4 27.1 4.7 31.3 20.1 21.0 27.8 88.1 23.6 15.5 20.8 57.2 21.0 27.7 49.9 20.4 14.1 7.0 29.3 25.4 14.9 19.5 18.5 55.2 19.2 40.7 16.4 14.9 11.2 37.9 16.7 16.0 18.7 10.4 20.3 18.6 33.7 66.1 20.8 10.3 28.2 27.0 21.5 9.5 22.0 37.9 40.0 6.6 35.5 46.7 51.2 44.3 19.6 19.0 9.7 16.2 35.4 17.1 12.7 DUSP11 PIR1 ENSG00000144048 "Dual specificity phosphatase 11" O75319 2 73762184-73780157 "Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021052 Supported "Nucleoplasm,Nucleoli fibrillar center,Cytokinetic bridge" Yes Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Nucleoli fibrillar center" "Cytokinetic bridge" "HPA021052: AB_2670577" "unprognostic (2.45e-3)" "unprognostic (1.06e-1)" "unprognostic (2.19e-2)" "unprognostic (7.87e-3)" "unprognostic (9.14e-2)" "unprognostic (5.28e-3)" "prognostic unfavorable (2.10e-7)" "unprognostic (7.20e-2)" "unprognostic (5.43e-2)" "unprognostic (5.85e-2)" "unprognostic (8.67e-3)" "unprognostic (3.84e-2)" "unprognostic (7.56e-3)" "unprognostic (1.41e-1)" "unprognostic (1.47e-1)" "unprognostic (1.47e-3)" "unprognostic (1.46e-1)" 16.0 13.3 7.9 17.1 7.7 35.2 20.4 13.4 11.2 22.4 7.6 16.0 17.3 21.2 19.3 30.5 39.0 15.9 14.2 8.1 6.9 20.2 17.9 14.3 25.3 6.1 5.7 23.5 11.0 14.7 14.0 20.5 6.1 16.5 17.4 8.3 16.0 14.4 14.3 27.6 15.3 19.6 4.8 19.0 16.3 16.8 6.5 24.8 16.5 17.8 26.1 25.2 22.4 8.3 39.4 16.7 17.6 18.6 31.2 38.7 31.2 28.2 36.7 35.8 36.4 24.2 29.1 50.6 17.7 30.6 32.1 26.7 22.0 56.8 34.3 35.2 22.9 31.2 12.0 37.3 32.7 35.5 28.0 31.6 67.3 32.1 44.1 31.1 40.4 24.2 33.6 28.6 40.2 21.3 34.3 37.6 28.4 36.7 22.7 13.6 47.3 46.0 29.3 32.1 25.9 14.1 26.1 30.6 35.7 21.0 16.4 18.6 23.1 25.4 31.4 29.5 33.7 30.7 26.2 68.1 23.5 35.5 25.3 72.5 42.2 99.5 56.3 39.3 73.5 68.3 65.8 67.4 47.3 65.9 69.4 65.5 65.2 69.8 40.6 35.7 88.6 71.7 7.9 7.7 13.4 11.2 8.1 6.9 6.1 5.7 6.1 4.8 6.5 8.3 26.5 9.6 12.0 7.5 39.5 83.2 55.1 93.0 39.3 11.0 12.9 15.1 8.6 27.1 45.7 12.9 4.2 32.8 34.8 15.5 50.9 29.6 9.1 18.0 15.7 34.6 12.0 21.0 14.9 27.3 42.0 26.5 16.3 13.6 40.7 20.5 52.1 15.3 30.7 5.0 12.7 18.0 36.7 20.2 27.1 7.0 28.9 17.0 23.2 10.3 34.8 9.8 41.2 13.0 13.8 28.2 17.8 25.6 31.8 30.0 22.8 50.4 38.2 16.6 6.6 18.2 23.1 23.8 34.6 42.8 83.0 38.6 39.8 20.7 18.8 60.9 DUSP18 DUSP20 ENSG00000167065 "Dual specificity phosphatase 18" Q8NEJ0 22 30652051-30667887 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 123.4;Late spermatids: 344.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034070, HPA051349" Uncertain Supported Nucleoplasm Yes No "Cluster 31: Non-specific - Inflammatory response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "CAB034070: AB_2094867, HPA051349: AB_2681450" "unprognostic (1.11e-1)" "unprognostic (2.34e-2)" "unprognostic (3.49e-3)" "unprognostic (4.88e-3)" "unprognostic (1.88e-1)" "unprognostic (9.12e-2)" "unprognostic (3.77e-4)" "unprognostic (1.83e-1)" "unprognostic (1.61e-1)" "unprognostic (3.53e-2)" "unprognostic (9.62e-2)" "unprognostic (4.87e-2)" "unprognostic (1.23e-3)" "unprognostic (6.55e-2)" "unprognostic (1.97e-1)" "unprognostic (4.56e-2)" "unprognostic (1.02e-1)" 3.3 1.9 3.4 4.5 3.6 3.3 2.8 2.9 5.3 2.4 9.1 5.4 5.0 2.9 4.9 4.1 10.9 4.2 2.0 3.7 4.0 2.2 1.0 5.5 4.7 5.4 7.6 2.4 2.9 3.3 4.2 2.1 4.9 2.1 6.8 5.2 2.5 2.4 1.3 4.8 4.6 3.8 4.8 4.3 4.8 13.9 4.5 4.0 3.3 1.6 3.9 3.3 2.6 6.0 5.4 5.4 2.5 5.8 6.2 11.9 2.3 4.9 5.3 4.7 5.1 3.1 5.3 3.6 3.3 6.0 6.2 3.8 1.3 3.8 5.3 9.8 6.1 1.5 2.2 2.2 2.6 7.4 5.3 3.1 5.4 7.8 3.0 5.3 15.0 4.1 1.7 2.8 5.2 4.8 4.2 1.8 0.8 6.4 3.3 2.8 1.7 1.2 5.6 3.7 6.2 3.7 4.8 1.7 3.5 3.2 4.5 2.2 11.1 9.9 5.4 2.7 2.8 2.1 2.6 1.7 11.4 1.3 5.0 31.4 15.3 29.9 8.6 19.3 6.6 9.7 9.6 7.7 17.2 8.7 6.6 7.5 31.8 7.4 21.4 9.7 13.2 8.4 3.4 3.6 2.9 5.3 3.7 4.0 5.4 7.6 4.9 4.8 4.5 6.0 7.2 19.2 5.4 11.4 7.1 21.4 13.3 6.5 2.2 2.9 4.9 3.4 2.0 10.0 9.6 5.5 45.9 1.2 12.0 10.0 3.9 10.1 123.4 34.5 5.0 10.1 35.5 2.1 8.0 9.4 3.9 6.8 8.6 5.0 7.0 4.4 13.9 1.1 8.1 1.7 4.4 15.4 6.1 15.6 28.5 344.2 8.4 13.2 8.8 13.1 13.9 10.1 9.2 1.5 14.3 9.3 15.4 6.8 3.9 8.8 24.2 4.1 64.6 16.8 6.6 8.6 6.6 63.0 17.2 5.7 21.3 1.0 9.7 3.5 19.0 8.7 DUSP19 "DUSP17, SKRP1" ENSG00000162999 "Dual specificity phosphatase 19" Q8WTR2 2 183078559-183100008 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 15.2;Endometrial ciliated cells: 17.7;Respiratory ciliated cells: 15.7;Spermatocytes: 15.5" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "amygdala: 1.3;basal ganglia: 2.4;cerebral cortex: 2.7;hippocampal formation: 3.8" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 7.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021501 Approved Approved Nucleoplasm Yes No "Cluster 35: T-regs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "HPA021501: AB_1847892" "unprognostic (1.24e-1)" "unprognostic (2.13e-2)" "unprognostic (1.21e-1)" "unprognostic (1.64e-1)" "unprognostic (5.18e-2)" "unprognostic (2.44e-1)" "unprognostic (1.21e-1)" "unprognostic (1.88e-1)" "unprognostic (8.30e-2)" "unprognostic (1.49e-2)" "unprognostic (3.33e-2)" "unprognostic (6.53e-2)" "unprognostic (5.80e-3)" "unprognostic (6.97e-2)" "unprognostic (2.91e-2)" "unprognostic (2.16e-2)" "unprognostic (2.75e-2)" 1.1 1.4 1.3 0.8 2.4 0.3 1.1 0.0 2.7 1.2 0.1 1.4 1.4 1.4 3.5 1.4 3.2 1.3 3.1 3.8 0.1 1.8 1.1 1.3 1.0 0.1 0.0 1.6 0.9 1.6 1.2 1.0 0.0 1.5 1.0 1.2 0.9 1.9 1.6 1.3 1.1 1.9 0.0 1.6 3.9 3.7 0.0 1.2 1.7 1.7 0.7 1.1 0.6 0.4 0.1 1.6 1.8 0.9 2.5 1.4 0.0 0.7 1.1 2.9 1.0 1.5 1.9 0.6 3.8 0.8 2.1 0.2 3.8 0.5 2.3 3.9 1.8 7.1 1.1 1.0 1.0 1.8 4.2 1.1 0.3 1.3 0.7 1.8 1.5 0.0 2.2 1.0 1.8 0.6 3.4 1.6 1.5 0.6 1.2 3.3 2.9 0.2 0.6 0.7 2.3 0.9 2.6 1.1 2.0 0.1 0.5 0.6 1.3 1.6 1.3 1.1 0.6 1.3 1.6 0.0 2.0 0.3 2.4 0.7 0.1 0.6 0.6 0.2 0.6 1.1 0.5 0.8 0.1 0.5 0.7 0.7 0.3 0.7 0.1 0.4 1.0 0.3 1.3 2.4 0.0 2.7 3.8 0.1 0.1 0.0 0.0 0.0 0.0 0.4 2.5 0.0 3.2 0.7 1.6 1.0 1.3 1.1 3.4 1.8 2.1 2.7 8.3 1.5 1.8 1.8 2.1 2.0 0.8 1.5 5.9 0.9 15.2 17.7 2.3 3.3 2.4 0.0 9.9 0.7 1.5 1.7 3.6 1.5 1.3 3.0 2.9 1.9 0.6 1.7 7.8 1.9 0.0 0.8 0.3 6.0 1.8 2.2 0.0 1.0 1.1 4.8 2.1 4.0 3.1 0.6 3.4 2.6 0.3 0.7 2.2 2.9 15.7 1.5 0.0 1.9 4.4 15.5 3.8 2.3 1.6 0.7 1.2 3.6 1.8 1.1 DVL3 KIAA0208 ENSG00000161202 "Dishevelled segment polarity protein 3" Q92997 3 184155377-184173614 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046486, HPA058265" Approved Approved "Intermediate filaments,Midbody ring,Centrosome" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 25: Spermatids - Spermatogenesis" "Midbody ring, Centrosome" "Intermediate filaments" "CAB046486: AB_10610845, HPA058265: AB_2683658" "unprognostic (2.20e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (1.88e-2)" "unprognostic (1.64e-2)" "unprognostic (2.23e-1)" "prognostic unfavorable (8.41e-4)" "unprognostic (8.61e-2)" "unprognostic (5.34e-2)" "unprognostic (2.49e-1)" "unprognostic (3.14e-1)" "prognostic unfavorable (4.77e-5)" "prognostic unfavorable (1.53e-8)" "unprognostic (1.87e-1)" "unprognostic (4.10e-1)" "unprognostic (8.41e-2)" "unprognostic (3.95e-1)" 35.2 28.1 16.4 18.7 17.4 18.6 29.8 17.4 18.9 39.0 15.9 46.0 17.2 44.7 16.1 30.3 34.5 22.6 35.0 16.4 17.1 25.7 20.0 31.7 13.9 18.1 17.3 42.0 25.6 17.9 24.4 38.3 17.6 29.1 16.1 22.8 25.6 25.8 34.9 33.8 27.1 31.7 16.6 25.6 27.9 15.1 17.0 12.4 30.0 22.3 15.9 36.6 31.6 18.3 47.9 13.6 36.4 41.4 37.5 37.8 95.0 28.4 28.9 32.7 27.6 43.6 18.3 33.6 73.3 37.0 32.4 40.8 29.6 22.2 23.4 54.0 32.2 38.1 21.3 28.2 56.6 21.2 27.8 38.4 39.9 23.4 27.3 55.9 24.6 21.6 38.9 44.2 35.5 46.5 28.3 25.2 32.8 34.6 22.1 49.9 42.7 30.0 31.7 36.2 36.3 51.0 34.9 39.8 67.4 35.8 98.7 26.8 25.0 29.5 28.5 31.0 43.8 48.3 38.8 37.0 30.0 22.4 23.6 0.1 0.6 1.3 0.6 1.0 0.8 0.7 0.4 0.7 0.6 0.5 0.5 0.3 0.9 0.4 0.3 0.8 0.2 0.4 16.4 17.4 17.4 18.9 16.4 17.1 18.1 17.3 17.6 16.6 17.0 18.3 15.9 25.6 14.1 16.6 10.8 18.7 15.7 12.9 15.9 20.1 23.5 16.5 26.9 12.8 17.2 22.0 27.1 34.4 14.6 40.8 23.5 13.3 12.8 23.2 30.9 15.9 34.3 6.9 11.4 16.6 21.6 22.6 32.6 27.7 17.1 29.7 19.2 20.5 20.3 62.2 11.8 22.3 12.2 16.2 14.4 47.5 33.5 17.4 12.4 14.0 10.8 19.7 14.4 9.0 11.5 20.7 18.9 37.2 13.9 20.8 25.2 18.3 13.4 18.5 19.7 23.6 27.1 10.6 12.4 20.4 21.7 52.1 10.3 21.9 21.5 25.7 DYRK1B MIRK ENSG00000105204 "Dual specificity tyrosine phosphorylation regulated kinase 1B" Q9Y463 19 39825350-39834201 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 131.3;testis: 83.8" "Group enriched" "Detected in many" 12 "Early spermatids: 179.4;Late spermatids: 580.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SH-SY5Y: 14.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028522, HPA028786" Uncertain Supported "Nucleoplasm,Mitotic chromosome" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Mitotic chromosome" "HPA028522: AB_2672656, HPA028786: AB_10670831" "unprognostic (2.22e-2)" "unprognostic (9.86e-2)" "unprognostic (4.55e-2)" "unprognostic (3.45e-3)" "unprognostic (1.96e-1)" "unprognostic (1.13e-2)" "unprognostic (2.25e-1)" "unprognostic (2.39e-1)" "unprognostic (6.02e-2)" "unprognostic (3.67e-2)" "unprognostic (8.93e-2)" "unprognostic (4.22e-2)" "prognostic favorable (8.83e-4)" "unprognostic (9.73e-2)" "unprognostic (1.12e-1)" "unprognostic (2.53e-2)" "unprognostic (3.88e-2)" 9.5 19.6 4.8 2.7 4.8 4.7 10.9 4.1 6.2 12.5 4.8 12.4 5.3 11.9 7.8 11.7 13.8 3.3 20.0 4.7 3.6 16.2 7.5 8.8 4.6 3.5 3.4 11.6 10.3 6.5 31.5 2.7 3.6 13.0 2.1 4.1 14.3 3.3 131.3 14.8 10.2 2.6 1.2 14.0 12.1 83.8 3.6 5.2 16.5 49.9 2.5 11.4 10.5 3.0 0.4 9.3 8.8 6.2 4.9 4.6 0.7 2.9 1.8 2.6 2.3 0.9 3.6 1.4 11.0 3.4 0.1 3.2 1.3 2.0 2.3 5.4 7.8 0.6 5.9 0.9 4.1 0.3 1.9 6.2 1.2 0.8 2.9 8.6 0.6 3.5 1.5 2.0 0.4 4.7 2.1 0.8 2.2 2.7 2.1 1.0 0.2 0.6 5.7 2.2 12.7 14.5 4.5 4.4 0.2 4.6 4.4 0.5 4.5 1.1 2.0 1.0 0.9 3.2 1.1 1.0 7.4 0.9 0.4 0.7 1.6 1.8 3.0 1.7 3.6 2.4 2.0 3.1 1.9 1.6 1.0 1.7 2.5 3.3 1.6 4.5 2.2 1.7 4.8 4.8 4.1 6.2 4.7 3.6 3.5 3.4 3.6 1.2 3.6 3.0 6.0 0.0 0.6 6.2 10.9 3.4 3.8 8.4 10.2 15.2 9.0 6.1 6.1 7.2 3.4 16.5 20.9 2.1 21.7 10.3 9.8 13.1 179.4 15.4 6.7 7.3 20.4 19.8 4.6 4.3 1.7 5.1 7.7 10.1 1.3 11.9 12.1 3.9 5.9 10.1 6.3 9.8 10.2 8.2 3.0 580.2 7.2 4.7 5.4 7.5 5.7 8.3 10.3 5.0 3.2 9.7 9.7 5.3 5.0 4.8 11.5 17.4 10.7 13.0 0.0 11.1 4.8 30.1 13.4 6.1 2.8 1.4 10.8 20.2 7.4 3.6 DYSF "FER1L1, LGMD2B" ENSG00000135636 Dysferlin O75923 2 71453722-71686768 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 95.3" "Cell type enhanced" "Detected in many" "Adipocytes: 30.5;Endothelial cells: 43.7;Excitatory neurons: 34.7;Hepatic stellate cells: 32.2;Kupffer cells: 27.1;Oligodendrocytes: 62.7;Syncytiotrophoblasts: 66.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 7 "neutrophil: 27.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 27.0" "Group enriched" "Detected in many" 5 "hTERT-RPE1: 31.9;HUVEC TERT2: 85.5;LHCN-M2: 75.3;RH-30: 78.5;TIME: 58.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002510, HPA017071, HPA021945" Enhanced Supported "Plasma membrane,Centriolar satellite" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Centriolar satellite" "CAB002510: AB_442097, HPA017071: AB_1847927, HPA021945: AB_1847928" "unprognostic (1.04e-1)" "unprognostic (7.66e-3)" "unprognostic (5.43e-3)" "unprognostic (1.66e-2)" "unprognostic (1.65e-1)" "unprognostic (2.42e-1)" "unprognostic (4.43e-2)" "unprognostic (1.14e-1)" "unprognostic (2.70e-1)" "unprognostic (3.21e-1)" "unprognostic (2.93e-1)" "unprognostic (6.43e-2)" "unprognostic (4.88e-3)" "unprognostic (1.22e-2)" "unprognostic (3.18e-2)" "unprognostic (1.36e-1)" "unprognostic (5.97e-3)" 10.1 1.7 1.0 11.5 1.1 31.6 4.3 4.1 7.7 1.9 0.7 7.0 2.0 2.3 0.5 7.4 3.2 4.6 16.8 0.2 3.8 3.6 6.5 8.3 3.7 14.8 5.1 1.3 1.5 2.3 1.5 21.1 13.7 3.3 2.5 0.5 1.3 4.8 95.3 1.2 3.1 10.2 2.0 21.4 2.5 1.1 10.2 2.3 4.6 32.3 0.9 6.9 1.8 1.8 1.1 0.0 3.3 3.0 0.0 0.0 6.1 0.1 0.8 2.2 1.5 0.4 1.0 0.0 12.1 0.1 3.4 2.5 0.0 1.2 1.1 0.0 0.0 0.2 0.2 0.0 0.3 0.1 0.0 1.5 0.0 2.3 10.6 31.9 85.5 0.2 8.4 0.0 75.3 0.0 0.0 5.8 8.1 0.0 0.9 0.0 78.5 0.0 2.6 0.2 0.0 0.0 4.1 0.7 0.1 7.9 0.3 0.8 58.1 0.3 3.8 0.2 1.1 0.0 0.0 0.0 0.0 13.3 0.0 0.0 4.1 0.1 0.5 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 27.0 0.4 0.1 0.0 0.0 1.4 1.0 1.1 4.1 7.7 0.2 3.8 14.8 5.1 13.7 2.0 10.2 1.8 30.5 3.2 8.1 1.0 1.0 2.4 0.0 0.1 0.0 1.1 0.3 0.6 24.0 0.0 1.3 0.0 0.0 8.1 0.7 0.1 0.0 0.4 4.8 0.7 1.3 43.7 0.0 2.7 34.7 0.2 3.8 2.2 0.0 9.3 2.5 0.3 32.2 13.4 11.4 0.0 13.0 0.2 0.0 27.1 3.0 6.0 0.6 10.2 0.0 16.9 5.8 0.1 0.0 2.5 62.7 0.1 0.0 0.7 0.1 0.2 0.0 2.1 0.7 0.2 6.6 5.2 5.5 0.6 1.1 0.1 1.6 66.2 1.1 0.9 0.0 0.1 DZIP1L "DZIP2, FLJ32844" ENSG00000158163 "DAZ interacting zinc finger protein 1 like" Q8IYY4 3 138061990-138115818 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 58.8;Respiratory ciliated cells: 74.0;Rod photoreceptor cells: 19.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030404 Approved Supported "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Microtubules "Nucleoplasm, Cytokinetic bridge" "HPA030404: AB_10601548" "unprognostic (3.65e-2)" "unprognostic (8.37e-2)" "unprognostic (2.87e-2)" "unprognostic (3.71e-2)" "unprognostic (8.22e-2)" "unprognostic (6.50e-2)" "unprognostic (6.47e-4)" "unprognostic (1.54e-1)" "unprognostic (3.21e-2)" "unprognostic (3.13e-1)" "unprognostic (3.26e-1)" "unprognostic (1.69e-1)" "unprognostic (1.51e-2)" "unprognostic (2.35e-3)" "unprognostic (2.72e-1)" "unprognostic (9.98e-2)" "unprognostic (2.77e-2)" 4.9 1.4 1.7 2.2 2.2 8.8 4.7 5.9 2.1 8.6 15.3 5.0 2.2 8.1 1.9 2.5 12.8 5.7 3.3 2.2 2.3 5.6 1.0 5.7 0.9 5.7 7.4 7.0 6.3 2.7 2.1 2.0 4.2 4.1 1.5 4.6 2.1 3.3 1.0 7.8 2.1 4.6 4.3 2.6 7.2 4.1 2.6 0.4 3.6 0.9 0.7 6.1 5.3 2.2 5.4 3.1 6.1 5.1 3.8 5.1 1.4 8.6 5.1 5.0 6.3 2.0 0.4 0.0 4.3 8.0 7.0 1.7 4.5 2.0 2.4 1.2 4.4 2.4 7.5 0.3 3.1 1.8 4.0 5.4 2.0 5.5 2.6 5.1 2.8 1.4 1.8 0.0 6.9 0.3 0.0 0.8 7.4 0.0 1.1 0.0 7.1 0.0 2.3 8.5 2.1 4.8 8.9 0.0 4.3 3.4 2.3 3.7 2.2 12.3 5.6 6.0 4.5 0.0 0.0 0.1 4.9 2.6 4.8 0.0 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 2.2 5.9 2.1 2.2 2.3 5.7 7.4 4.2 4.3 2.6 2.2 1.4 3.2 2.0 4.2 0.0 3.6 0.6 1.9 7.4 8.6 0.2 2.5 2.9 7.2 7.7 1.8 8.4 0.1 0.0 0.0 5.9 3.8 17.4 58.8 8.5 2.6 0.0 1.3 4.0 1.2 0.1 6.5 7.1 1.1 0.0 7.4 0.0 0.0 1.4 3.3 2.9 0.0 2.0 3.2 2.6 1.8 6.2 3.5 0.0 3.7 0.6 2.7 0.0 2.5 0.2 5.9 0.0 4.1 0.0 0.4 0.0 0.8 74.0 19.4 0.0 7.2 9.8 0.6 2.3 1.7 4.3 0.0 0.5 1.7 0.0 0.1 EBNA1BP2 "EBP2, NOBP, P40" ENSG00000117395 "EBNA1 binding protein 2" Q99848 1 43164175-43270936 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026512, HPA028277" Approved Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 38000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA026512: AB_1847954, HPA028277: AB_10603664" "unprognostic (9.30e-2)" "unprognostic (2.02e-1)" "unprognostic (1.05e-3)" "unprognostic (2.03e-2)" "unprognostic (8.59e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (4.22e-4)" "unprognostic (7.64e-3)" "unprognostic (2.89e-2)" "unprognostic (1.24e-3)" "unprognostic (7.11e-2)" "unprognostic (1.64e-3)" "unprognostic (4.10e-3)" "unprognostic (3.04e-3)" "unprognostic (1.69e-1)" "unprognostic (3.22e-2)" "unprognostic (1.33e-2)" 35.1 38.8 30.3 35.2 31.1 34.3 39.5 28.8 33.5 30.0 32.5 35.4 23.6 35.5 55.7 46.5 43.5 21.7 37.1 31.1 31.0 55.7 126.6 27.7 35.9 29.3 28.5 27.3 36.1 45.6 48.9 33.1 30.0 29.0 36.5 19.6 34.5 31.0 51.9 36.8 24.5 35.0 29.6 24.8 33.4 44.4 31.8 30.5 41.4 28.6 39.8 52.5 34.5 31.1 325.0 180.2 66.0 192.7 52.1 58.3 142.6 219.4 107.8 338.7 210.5 215.2 192.5 211.0 167.9 157.0 157.2 218.2 144.5 200.9 360.5 101.2 146.5 144.8 160.9 188.5 95.7 248.7 106.8 47.6 197.4 248.6 197.3 64.2 185.5 145.2 220.3 67.8 165.1 172.8 190.0 152.0 290.8 209.5 165.0 139.2 150.4 235.5 123.7 135.0 132.0 139.9 127.3 228.6 219.0 105.6 94.5 136.1 147.6 128.7 248.9 211.4 360.7 102.9 219.7 262.7 107.6 258.7 265.2 19.7 45.4 24.9 52.3 54.1 55.2 61.5 52.8 54.5 68.7 68.5 48.3 48.3 3.9 59.6 53.3 65.6 60.5 43.6 30.3 31.1 28.8 33.5 31.1 31.0 29.3 28.5 30.0 29.6 31.8 31.1 38.0 35.3 39.5 5.9 36.9 123.0 91.6 78.0 40.5 26.3 50.6 62.1 32.0 52.9 52.5 31.3 6.2 102.2 23.3 34.0 90.1 144.5 163.5 56.8 47.3 51.0 24.1 45.0 5.6 124.4 135.1 51.5 33.1 31.6 50.7 35.1 27.8 148.3 63.3 15.2 3.8 49.7 48.8 22.5 24.7 94.9 33.2 28.9 55.2 3.7 41.4 55.7 35.0 6.0 4.9 135.3 25.8 38.4 53.1 179.3 29.4 135.9 81.3 29.5 39.5 55.0 68.1 92.6 97.8 54.2 99.4 84.3 26.8 57.8 66.2 95.3 ECD "GCR2, hSGT1" ENSG00000122882 "Ecdysoneless cell cycle regulator" O95905 10 73130155-73169055 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006465 Approved Supported Nucleoplasm,Cytosol Yes No "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Cytosol" "HPA006465: AB_2667595" "unprognostic (2.70e-1)" "unprognostic (1.94e-1)" "unprognostic (6.46e-2)" "unprognostic (2.19e-1)" "unprognostic (2.75e-2)" "unprognostic (4.71e-3)" "prognostic unfavorable (6.87e-4)" "unprognostic (1.22e-1)" "unprognostic (3.55e-2)" "unprognostic (6.61e-2)" "unprognostic (3.07e-2)" "unprognostic (1.06e-1)" "unprognostic (2.54e-2)" "unprognostic (1.05e-1)" "unprognostic (6.77e-2)" "unprognostic (7.05e-2)" "unprognostic (3.84e-2)" 13.8 17.2 8.0 14.6 11.2 31.9 17.9 12.7 10.7 14.8 10.2 13.1 12.1 16.0 16.2 15.2 11.9 15.9 12.8 8.5 7.7 17.4 18.9 12.6 17.7 7.4 7.1 13.9 16.7 22.8 11.3 17.8 7.5 16.5 13.9 17.0 14.4 14.3 13.8 15.3 11.7 14.7 7.2 14.4 13.1 19.2 7.6 21.0 19.0 14.3 18.4 20.0 12.5 12.5 41.0 28.8 32.0 48.1 28.8 28.2 26.3 31.1 48.5 49.9 57.8 52.0 41.4 31.8 29.9 30.5 36.7 33.0 34.6 36.9 50.3 26.1 33.5 39.9 21.2 38.0 43.7 48.3 25.3 31.5 30.9 41.6 51.7 37.9 53.3 29.3 42.1 21.4 47.6 34.8 44.5 28.6 33.0 37.7 81.8 32.1 35.6 17.6 40.4 29.5 13.9 26.5 28.4 62.5 40.3 32.6 36.1 23.0 33.3 21.1 42.8 23.3 36.2 25.2 18.1 54.5 40.1 40.4 18.5 21.0 23.3 26.3 24.7 24.9 26.4 24.3 23.0 24.4 20.3 21.2 29.9 21.5 27.5 32.5 34.7 13.8 24.8 20.3 8.0 11.2 12.7 10.7 8.5 7.7 7.4 7.1 7.5 7.2 7.6 12.5 21.2 28.9 12.1 13.1 22.7 11.0 27.9 16.6 24.5 13.9 11.9 10.3 12.5 8.6 23.0 7.3 25.0 22.7 22.7 9.0 7.9 15.8 39.4 15.3 15.5 17.4 10.8 21.8 17.3 12.2 15.7 15.7 23.4 24.8 19.6 12.2 15.0 8.8 16.6 20.2 16.3 11.8 8.2 12.4 10.1 11.5 15.8 16.0 14.2 9.4 10.8 10.3 14.4 11.6 18.6 14.7 5.7 13.2 16.7 13.1 9.8 12.2 10.5 13.1 6.6 17.8 18.2 32.9 16.0 19.2 10.9 33.2 22.1 11.6 9.2 24.7 ECM2 ENSG00000106823 "Extracellular matrix protein 2" O94769 9 92493554-92536655 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 122.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 73.3;Hepatocytes: 49.3;Leydig cells: 122.1;Peritubular cells: 69.6;Skeletal myocytes: 43.6;Smooth muscle cells: 50.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "ASC diff: 19.1;ASC TERT1: 34.5;HSkMC: 36.8;hTCEpi: 42.8;hTERT-HME1: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035347, HPA035348" Approved Approved "Mitotic spindle,Centrosome,Cytosol" "Secreted to extracellular matrix" Yes NA 10000000 "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Centrosome, Cytosol" "Mitotic spindle" "HPA035347: AB_10669856, HPA035348: " "unprognostic (2.48e-1)" "unprognostic (2.11e-1)" "unprognostic (2.27e-2)" "unprognostic (2.20e-2)" "unprognostic (5.35e-2)" "unprognostic (2.30e-1)" "prognostic favorable (4.50e-5)" "unprognostic (6.14e-2)" "unprognostic (2.14e-2)" "unprognostic (1.79e-1)" "unprognostic (1.66e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (4.09e-6)" "unprognostic (1.12e-3)" "unprognostic (2.39e-2)" "unprognostic (3.80e-2)" "unprognostic (6.63e-3)" 122.1 14.3 5.0 2.1 5.0 0.6 34.8 6.0 4.9 43.5 8.1 6.8 9.0 40.8 23.2 9.0 30.0 31.7 31.5 4.5 11.6 28.4 81.5 22.5 8.3 5.2 10.3 91.6 6.3 9.1 6.1 3.5 5.8 21.2 7.4 0.3 7.2 22.2 7.4 9.7 14.8 27.8 4.4 0.9 4.3 16.8 8.0 5.0 11.4 24.6 7.8 13.3 11.1 12.0 0.7 0.1 0.4 0.0 19.1 34.5 1.3 0.8 1.1 0.1 0.5 0.6 0.0 0.0 0.1 1.9 0.3 0.5 0.9 0.8 0.1 4.4 0.0 0.0 0.0 0.0 3.3 0.2 0.0 36.8 42.8 0.9 11.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.7 0.5 0.1 0.0 0.1 0.0 2.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 5.0 6.0 4.9 4.5 11.6 5.2 10.3 5.8 4.4 8.0 12.0 12.9 0.0 2.3 5.5 0.3 11.5 0.1 0.6 0.6 3.0 0.3 1.3 5.5 1.5 2.0 0.0 2.1 0.1 0.3 0.2 0.0 0.1 5.1 0.6 18.6 5.2 0.0 0.8 3.4 0.0 16.2 73.3 0.5 0.5 0.0 18.2 2.2 49.3 0.4 0.0 2.8 0.4 0.0 1.3 15.4 8.9 122.1 1.1 5.4 17.8 0.1 0.1 0.0 0.5 2.9 0.0 0.2 69.6 1.4 0.1 11.1 9.2 3.3 2.5 26.3 43.6 50.2 0.9 0.6 0.9 9.1 0.8 0.9 13.5 0.6 0.2 ECPAS "ECM29, FLJ22036, KIAA0368" ENSG00000136813 "Ecm29 proteasome adaptor and scaffold" Q5VYK3 9 111360692-111484745 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 245.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Alveolar cells type 2: 63.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021646, HPA059795" Uncertain Approved Nucleoplasm Yes No 5400 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA021646: AB_2670788, HPA059795: AB_2684127" "unprognostic (1.64e-1)" "unprognostic (1.57e-1)" "unprognostic (7.42e-2)" "unprognostic (5.72e-2)" "unprognostic (3.81e-1)" "unprognostic (1.79e-1)" "unprognostic (1.80e-2)" "unprognostic (5.12e-2)" "unprognostic (2.02e-1)" "unprognostic (2.17e-1)" "unprognostic (9.99e-2)" "unprognostic (1.67e-1)" "unprognostic (3.72e-3)" "unprognostic (2.67e-1)" "unprognostic (1.34e-1)" "unprognostic (2.09e-1)" "unprognostic (1.05e-1)" 41.6 34.1 33.8 23.5 43.7 28.6 31.8 33.9 52.9 31.6 31.6 34.0 32.1 28.4 23.6 28.7 26.5 19.9 44.4 52.7 30.6 31.0 28.2 31.0 21.6 32.0 31.9 33.0 38.4 40.6 32.7 24.0 33.7 34.3 29.6 28.3 32.0 25.6 245.0 32.4 29.6 28.5 26.1 22.4 31.2 35.6 31.4 16.2 32.4 97.1 21.2 31.6 30.9 40.1 58.9 53.1 35.0 37.7 81.6 81.1 57.5 70.8 60.4 57.0 39.1 49.7 35.6 59.3 32.5 62.6 46.5 83.7 45.1 47.4 52.7 65.4 28.3 36.6 64.5 72.0 60.4 68.9 38.2 74.2 48.8 57.3 84.4 64.6 58.8 14.7 85.4 81.1 47.1 49.5 0.3 39.9 68.6 74.7 44.1 33.4 107.2 35.7 48.9 52.2 66.7 31.7 60.5 64.1 46.2 37.6 50.5 36.4 64.7 38.1 43.6 57.5 65.5 71.2 144.9 71.3 55.7 27.8 36.0 2.7 5.8 1.9 4.6 6.0 5.3 3.9 4.7 5.3 8.1 4.2 2.8 4.9 1.7 4.8 4.5 3.6 4.1 2.9 33.8 43.7 33.9 52.9 52.7 30.6 32.0 31.9 33.7 26.1 31.4 40.1 24.6 57.7 63.9 0.0 5.3 0.0 0.0 0.0 0.0 0.0 19.0 14.7 0.0 0.0 32.8 12.9 0.0 17.3 11.6 0.0 9.8 21.0 0.0 19.3 32.0 12.1 0.0 0.0 0.0 21.7 11.4 12.5 0.0 26.2 24.0 30.6 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 10.9 0.0 0.0 0.0 0.0 25.7 0.0 0.0 4.9 0.0 0.0 14.4 24.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 20.2 6.5 29.2 0.0 0.0 EEF1AKMT3 "DKFZP586D0919, FAM119B, METTL21B" ENSG00000123427 "EEF1A lysine methyltransferase 3" Q96AZ1 12 57771492-57782541 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 14.9;Breast myoepithelial cells: 7.6;Exocrine glandular cells: 12.7;monocytes: 8.8;Proximal tubular cells: 16.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in all" 7 "RH-30: 152.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA043020, HPA045492" Uncertain Approved "Nucleoplasm,Mitotic chromosome,Centrosome" Yes NA "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 7: Non-specific - Mitochondria" Centrosome "Nucleoplasm, Mitotic chromosome" "HPA043020: AB_2678274, HPA045492: " "unprognostic (2.00e-1)" "unprognostic (6.52e-2)" "unprognostic (7.96e-2)" "unprognostic (1.60e-1)" "unprognostic (1.53e-1)" "unprognostic (2.01e-1)" "unprognostic (1.55e-3)" "unprognostic (1.06e-1)" "unprognostic (7.34e-3)" "unprognostic (7.52e-3)" "unprognostic (1.66e-1)" "unprognostic (2.32e-1)" "unprognostic (1.54e-3)" "unprognostic (5.77e-2)" "unprognostic (1.33e-1)" "unprognostic (1.34e-2)" "unprognostic (1.23e-1)" 7.5 6.2 2.5 3.6 2.3 2.6 9.2 4.1 2.7 10.5 2.6 5.6 3.9 9.3 9.6 5.6 8.4 5.4 3.7 2.4 1.8 11.6 6.5 5.3 3.6 2.6 2.4 11.4 21.7 6.4 3.7 4.6 2.7 8.2 4.6 3.7 19.4 8.7 2.9 7.3 3.8 7.6 2.1 4.0 7.2 4.2 2.4 1.9 10.1 3.1 3.1 6.3 7.3 3.1 5.4 11.0 4.6 5.9 12.8 12.0 4.0 5.8 10.9 8.9 9.0 5.6 9.5 3.1 7.4 7.6 7.2 5.2 3.7 3.3 9.3 4.0 5.6 14.9 6.6 9.2 11.3 3.7 6.6 12.6 8.7 9.3 9.8 15.2 9.7 13.2 8.9 22.6 5.4 3.8 4.7 11.0 3.4 4.3 8.0 8.5 152.1 10.0 6.0 5.3 4.4 6.0 10.0 7.5 6.2 4.1 11.9 10.0 9.5 13.7 7.7 5.8 6.4 5.7 2.3 3.8 11.3 15.4 10.0 0.4 3.0 0.1 1.8 1.1 7.8 0.5 3.5 2.2 3.1 0.4 1.7 1.4 0.7 1.5 4.6 1.5 2.2 2.3 2.5 2.3 4.1 2.7 2.4 1.8 2.6 2.4 2.7 2.1 2.4 3.1 3.9 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 14.9 7.6 0.0 0.0 1.8 1.8 0.0 3.4 1.3 0.0 5.9 5.5 0.0 2.0 6.0 1.9 0.0 0.0 0.0 12.7 4.9 3.4 0.0 2.5 2.5 5.4 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 8.8 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.1 0.0 0.0 16.4 1.5 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 1.6 0.5 4.7 0.0 0.0 EFCAB12 C3orf25 ENSG00000172771 "EF-hand calcium binding domain 12" Q6NXP0 3 129401321-129428651 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 12.6;fallopian tube: 19.7" "Group enriched" "Detected in some" 4 "Early spermatids: 29.6;Endometrial ciliated cells: 31.9;Late spermatids: 20.1;Respiratory ciliated cells: 46.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 1.5;RPTEC TERT1: 1.2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 8.9" "HPA037694, HPA057532" Uncertain Supported Approved "Nucleoplasm,Nuclear bodies,Midbody ring" Yes NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Nuclear bodies, Midbody ring" "HPA037694: AB_10672605, HPA057532: " "unprognostic (2.06e-3)" "unprognostic (1.87e-2)" "unprognostic (2.96e-2)" "unprognostic (4.34e-3)" "unprognostic (1.81e-1)" "unprognostic (7.59e-4)" "unprognostic (2.37e-2)" "unprognostic (2.60e-1)" "unprognostic (1.13e-1)" "unprognostic (1.64e-1)" "unprognostic (1.81e-2)" "unprognostic (3.84e-1)" "unprognostic (1.20e-1)" "unprognostic (5.72e-2)" "unprognostic (2.27e-1)" "unprognostic (1.57e-2)" "unprognostic (4.59e-2)" 0.3 0.4 0.8 0.1 1.0 0.8 0.3 1.7 1.1 1.1 12.6 0.1 0.0 0.3 0.8 0.0 19.7 0.2 0.3 1.4 1.5 0.8 1.2 1.7 0.1 4.9 7.0 1.0 0.6 1.7 3.6 0.1 3.2 3.0 0.0 1.6 0.2 0.2 0.0 0.1 0.3 0.0 3.6 0.4 0.7 6.9 2.4 0.2 1.2 0.0 0.2 0.0 0.1 1.0 0.1 0.7 0.2 0.7 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.4 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.2 0.2 1.5 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.4 0.4 0.3 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.3 0.0 0.1 1.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.3 0.0 0.4 0.6 0.7 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 1.0 1.7 1.1 1.4 1.5 4.9 7.0 3.2 3.6 2.4 1.0 0.2 3.2 1.7 0.3 0.5 0.5 0.1 0.8 0.0 0.4 0.7 0.4 1.3 1.5 1.8 0.0 2.1 0.0 0.3 0.1 0.0 0.2 29.6 31.9 0.7 0.5 0.0 0.0 2.7 0.2 0.1 0.5 3.1 1.9 0.0 0.1 0.0 1.1 0.1 5.0 0.8 0.3 2.0 0.0 0.0 20.1 0.3 0.3 0.0 0.0 0.1 1.2 1.0 0.0 0.1 0.0 0.0 0.0 0.2 0.9 0.0 0.9 46.0 5.6 0.0 0.5 0.6 6.8 2.7 0.7 0.3 0.0 0.3 0.3 0.0 0.2 EIF3A "EIF3, eIF3-p170, eIF3-theta, EIF3S10, KIAA0139, TIF32" ENSG00000107581 "Eukaryotic translation initiation factor 3 subunit A" Q14152 10 119033670-119080823 "Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038315, HPA038316" Enhanced Supported Nucleoplasm,Cytosol Yes No 110000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 32: U-937 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "HPA038315: AB_10672588, HPA038316: AB_10673168" "unprognostic (8.15e-2)" "unprognostic (2.09e-2)" "unprognostic (2.65e-1)" "unprognostic (1.22e-1)" "unprognostic (4.53e-3)" "unprognostic (3.19e-1)" "unprognostic (1.47e-1)" "unprognostic (2.16e-1)" "unprognostic (1.84e-1)" "unprognostic (9.38e-2)" "unprognostic (3.84e-3)" "unprognostic (9.07e-2)" "unprognostic (5.48e-3)" "unprognostic (8.07e-2)" "unprognostic (1.20e-1)" "unprognostic (9.07e-2)" "unprognostic (1.89e-2)" 83.0 53.2 27.5 73.7 30.9 120.7 62.5 28.4 31.8 48.8 38.0 62.9 65.8 60.1 34.9 69.3 44.8 50.1 69.0 25.7 33.7 58.1 77.9 49.5 75.1 34.8 30.0 61.7 155.1 70.2 24.4 57.0 35.4 55.5 63.9 31.6 73.3 46.3 178.2 69.9 60.0 62.8 31.6 57.4 72.8 44.8 32.4 78.3 70.3 89.8 74.6 76.4 51.8 32.4 258.5 190.9 154.0 211.6 163.6 235.0 119.4 228.9 235.9 144.0 143.7 181.2 165.5 300.2 83.2 190.3 113.3 252.0 202.5 175.7 203.5 166.1 166.3 258.3 143.6 203.2 186.2 382.3 183.9 204.6 193.0 212.7 362.8 240.7 165.7 119.8 269.7 191.9 188.7 152.5 159.4 179.8 147.8 99.4 96.3 162.1 332.1 143.7 137.0 213.9 71.6 151.3 180.2 166.9 244.9 132.0 107.2 241.1 245.6 138.7 128.0 147.1 335.8 164.9 194.0 286.9 147.2 368.2 97.6 49.0 38.2 23.9 27.4 41.8 31.7 25.6 33.1 25.2 36.1 24.7 22.6 24.7 10.0 26.6 58.1 20.5 50.9 28.3 27.5 30.9 28.4 31.8 25.7 33.7 34.8 30.0 35.4 31.6 32.4 32.4 122.1 233.9 323.8 24.5 147.3 304.2 279.1 129.0 203.7 60.1 155.8 133.7 320.7 111.5 198.5 64.4 62.6 169.1 181.1 130.2 27.4 157.2 199.4 230.3 248.6 145.3 141.2 270.0 32.7 185.4 159.5 152.5 159.0 371.8 145.4 132.6 74.3 184.5 126.3 43.7 34.9 168.2 87.5 200.3 169.0 119.1 108.7 196.5 147.7 29.0 235.9 78.2 135.9 24.6 38.9 192.8 105.4 117.8 258.6 253.6 98.5 58.7 158.3 54.1 59.2 209.7 221.6 158.0 112.9 255.3 363.8 252.3 171.1 145.0 227.7 302.3 ELL3 FLJ22637 ENSG00000128886 "Elongation factor for RNA polymerase II 3" Q9HB65 15 43772605-43777315 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 57.7;skin 1: 25.0" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 5.2;Gastric mucus-secreting cells: 4.6;Proximal enterocytes: 6.5;Squamous epithelial cells: 21.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 10.5;naive B-cell: 15.9" "Lineage enriched" "Detected in many" 7 "B-cells: 15.9" "Cell line enhanced" "Detected in many" "Daudi: 73.8;OE19: 28.5;T-47d: 39.0;U-698: 149.9" "Region enriched" "Detected in single" 11 "olfactory bulb: 1.9" "Not detected" "Not detected" "HPA028938, HPA073494" Approved Supported "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nucleoli" "Mitotic chromosome" "HPA028938: AB_10795352, HPA073494: " "unprognostic (2.59e-2)" "unprognostic (4.41e-1)" "unprognostic (1.76e-1)" "unprognostic (1.28e-1)" "unprognostic (3.59e-1)" "unprognostic (2.30e-2)" "unprognostic (1.17e-1)" "unprognostic (2.42e-3)" "unprognostic (1.52e-2)" "unprognostic (3.89e-1)" "unprognostic (2.19e-1)" "unprognostic (3.53e-1)" "unprognostic (1.87e-1)" "unprognostic (3.67e-2)" "unprognostic (8.95e-2)" "unprognostic (1.08e-1)" "unprognostic (1.24e-2)" 0.5 0.9 1.0 9.7 1.0 0.2 5.2 1.0 1.1 1.6 4.7 8.0 14.1 0.6 1.1 4.5 3.9 0.7 0.5 1.0 1.1 1.4 0.7 1.5 49.7 1.0 1.1 1.7 0.4 1.6 0.5 3.7 1.1 2.0 12.3 0.1 2.2 1.0 0.4 25.0 12.9 1.0 1.0 1.0 1.8 16.2 1.4 1.5 0.7 1.9 57.7 0.7 0.8 1.1 2.1 0.2 0.6 1.1 4.9 1.2 0.4 0.2 1.3 2.8 3.1 0.0 1.3 73.8 0.1 1.2 0.1 13.7 1.3 0.7 1.4 1.6 7.3 0.4 2.6 4.6 1.0 0.1 0.0 1.4 12.3 0.7 0.2 0.2 1.1 0.4 0.2 0.0 0.7 4.0 1.5 1.4 0.1 28.5 2.4 0.8 0.0 0.0 1.8 0.0 9.5 0.0 1.7 21.5 0.0 0.3 39.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 149.9 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.1 0.2 10.5 0.6 0.1 0.0 15.9 1.1 0.2 0.0 0.1 0.0 2.2 0.6 0.6 1.0 1.0 1.0 1.1 1.0 1.1 1.0 1.1 1.1 1.0 1.4 1.1 0.1 0.0 0.0 0.0 2.2 0.4 0.1 0.2 5.2 0.0 0.7 0.5 0.0 0.0 0.2 0.0 0.0 0.1 0.3 1.2 0.0 0.1 1.8 0.4 0.1 0.2 0.0 0.4 0.1 0.7 0.0 0.5 4.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 2.5 0.0 0.0 0.5 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.1 6.5 0.1 3.1 0.0 0.0 0.2 0.4 0.2 0.2 21.0 1.0 0.3 0.1 0.1 2.3 0.2 EMG1 "C2F, Grcc2f, NEP1" ENSG00000126749 "EMG1 N1-specific pseudouridine methyltransferase" Q92979 12 6970913-6997428 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Methyltransferase, RNA-binding, rRNA-binding, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039304, HPA039666" Supported Supported "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 10: Non-specific - Unknown function" "Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA039304: AB_2676432, HPA039666: AB_10672891" "unprognostic (1.23e-1)" "unprognostic (1.17e-1)" "unprognostic (6.77e-2)" "unprognostic (1.35e-2)" "unprognostic (2.11e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (3.69e-4)" "unprognostic (2.70e-1)" "unprognostic (1.03e-1)" "unprognostic (2.12e-1)" "unprognostic (9.03e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (2.83e-6)" "unprognostic (2.13e-1)" "unprognostic (2.34e-1)" "unprognostic (6.75e-2)" "unprognostic (1.62e-1)" 16.8 18.0 13.0 15.2 14.2 12.6 17.3 14.4 20.2 14.9 15.9 14.0 11.1 14.5 13.6 20.2 16.1 4.6 22.6 13.2 14.1 23.2 22.8 15.9 13.4 14.4 14.2 13.9 13.6 9.4 12.8 8.6 14.5 15.7 9.7 9.3 13.6 6.1 21.2 17.4 14.0 7.4 14.3 18.1 14.6 9.9 14.0 12.3 15.6 12.8 12.8 16.1 14.1 15.3 55.5 53.7 20.5 25.2 15.8 11.5 84.7 40.1 17.9 31.2 21.2 106.4 57.6 55.4 14.7 25.1 56.8 39.8 18.9 46.1 35.2 40.1 30.6 76.8 51.7 99.6 20.3 79.0 47.8 18.5 27.2 45.5 51.8 16.2 13.9 38.6 38.6 12.1 29.8 65.3 41.4 48.3 169.6 45.4 28.0 56.3 41.2 44.0 20.0 68.8 11.9 35.7 42.2 43.9 41.4 57.5 12.0 57.8 29.2 32.4 42.6 26.8 92.9 14.6 17.9 97.7 34.8 33.7 52.8 15.5 44.1 22.3 60.7 66.4 63.3 85.3 63.6 67.6 51.2 88.0 74.4 69.1 6.2 60.9 86.4 55.8 68.1 81.3 13.0 14.2 14.4 20.2 13.2 14.1 14.4 14.2 14.5 14.3 14.0 15.3 30.1 16.0 41.3 1.3 34.0 36.6 92.2 79.1 25.0 14.7 29.0 36.8 0.0 24.3 60.9 42.3 8.4 107.3 22.8 18.1 49.0 75.3 9.6 23.1 24.8 32.3 9.6 16.0 1.3 66.8 121.0 31.8 11.7 22.7 60.9 27.7 23.2 35.9 65.4 16.8 1.4 25.7 71.2 25.0 29.3 15.5 37.9 27.7 28.4 1.9 45.1 24.5 43.3 2.0 2.7 75.7 19.8 25.9 17.3 69.0 25.1 81.1 54.0 16.0 39.5 29.2 86.5 28.9 59.7 28.4 39.9 74.3 30.6 46.4 35.7 75.8 EMILIN3 "C20orf130, dJ620E11.4, EMILIN5" ENSG00000183798 "Elastin microfibril interfacer 3" Q9NT22 20 41359962-41366818 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "epididymis: 53.6" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 17.7;Granulosa cells: 7.6;Microglial cells: 4.7;Oligodendrocyte precursor cells: 3.5;Peritubular cells: 4.9;Skeletal myocytes: 3.2" "Group enriched" "Detected in many" 5 "glioma: 10.8;testis cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.3;HAP1: 11.1;NTERA-2: 7.0;SCLC-21H: 13.0" "Region enriched" "Detected in single" 30 "cerebellum: 3.3" "Region enriched" "Detected in single" 4 "spinal cord: 4.1" "HPA044034, HPA059912, HPA078559" Enhanced Approved "Golgi apparatus,Microtubules,Cytokinetic bridge" "Secreted to extracellular matrix" Yes NA 1200000 "Cluster 68: Epididymis - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 36: Stromal cells - Cell proliferation" "Golgi apparatus" "Microtubules, Cytokinetic bridge" "HPA044034: AB_2678783, HPA059912: AB_2684158, HPA078559: " "unprognostic (1.66e-4)" "unprognostic (1.85e-2)" "unprognostic (2.50e-2)" "unprognostic (2.14e-1)" "unprognostic (2.65e-1)" "unprognostic (2.15e-2)" "unprognostic (1.71e-1)" "unprognostic (7.66e-2)" "unprognostic (2.18e-3)" "unprognostic (2.57e-1)" "unprognostic (6.54e-2)" "unprognostic (7.66e-2)" "unprognostic (3.13e-7)" "unprognostic (2.64e-2)" "unprognostic (1.05e-1)" "unprognostic (1.97e-1)" "unprognostic (9.62e-2)" 0.6 1.4 2.5 0.1 2.4 0.0 3.5 2.3 3.8 8.6 1.8 4.9 0.6 2.3 53.6 0.8 4.2 0.3 7.8 2.1 2.2 1.0 0.6 0.3 0.1 3.7 2.7 8.9 0.2 0.1 1.8 0.0 3.0 6.7 0.3 0.0 1.0 9.9 0.9 3.9 1.7 0.9 2.5 0.1 2.0 1.7 2.6 0.5 0.3 2.6 0.2 2.3 4.7 3.0 0.0 0.1 6.3 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.4 0.0 11.1 0.0 0.2 0.0 1.3 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 13.0 1.3 0.0 0.0 0.0 2.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.4 2.3 3.8 2.1 2.2 3.7 2.7 3.0 2.5 2.6 3.0 0.6 0.0 0.0 0.7 0.0 0.9 0.2 0.0 0.0 0.3 1.2 2.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 17.7 0.4 0.0 0.0 1.1 0.0 0.0 0.8 0.0 0.7 0.0 7.6 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.3 1.8 0.1 0.0 4.7 0.0 0.1 0.0 3.5 0.1 0.0 1.2 4.9 0.0 0.2 0.3 0.1 0.0 0.0 0.0 3.2 0.6 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.1 EMX1 ENSG00000135638 "Empty spiracles homeobox 1" Q04741 2 72916260-72936071 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 13.1;kidney: 36.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 55.2;Excitatory neurons: 13.0;Proximal tubular cells: 35.7" "Cancer enriched" "Detected in some" 5 "renal cancer: 3.7" "Region enriched" "Detected in some" 10 "cerebral cortex: 13.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.3;CACO-2: 3.7;HEK 293: 8.3;HMC-1: 1.6;RPTEC TERT1: 1.4;U-2 OS: 1.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 17 "amygdala: 2.7;cerebral cortex: 10.5;hippocampal formation: 7.8" "HPA006230, HPA006421" Approved Supported "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 7: Kidney - Transmembrane transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA006230: AB_2667542, HPA006421: AB_1078739" "unprognostic (4.54e-2)" "unprognostic (5.59e-2)" "unprognostic (8.71e-2)" "unprognostic (2.22e-6)" "unprognostic (4.82e-2)" "unprognostic (1.70e-1)" "unprognostic (1.94e-1)" "unprognostic (2.16e-1)" "unprognostic (1.29e-1)" "unprognostic (1.04e-1)" "unprognostic (2.99e-1)" "unprognostic (3.07e-1)" "prognostic favorable (1.54e-6)" "unprognostic (4.08e-2)" "unprognostic (1.44e-1)" "unprognostic (1.08e-3)" "unprognostic (5.02e-2)" 0.2 0.1 0.1 0.0 1.3 0.0 0.0 0.0 13.1 0.0 0.0 0.4 0.8 0.0 0.7 0.1 0.0 0.0 0.0 1.3 0.0 36.4 0.1 0.0 0.0 0.0 0.0 0.0 0.3 5.9 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.3 3.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.0 2.3 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.3 0.0 0.0 1.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.3 0.0 13.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 55.2 0.0 0.1 0.0 1.2 5.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 13.0 0.4 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.6 0.0 0.0 0.0 1.6 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.9 35.7 0.0 0.0 0.0 0.0 0.0 1.5 5.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 ENKD1 "C16orf48, DKFZP434A1319, FBB11" ENSG00000124074 "Enkurin domain containing 1" Q9H0I2 16 67662945-67667265 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 34.2;Endometrial ciliated cells: 38.3;Respiratory ciliated cells: 42.5;Spermatocytes: 37.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041163, HPA041478" Approved Approved "Plasma membrane,Centrosome,Cytosol" Yes No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Centrosome" Cytosol "HPA041163: AB_10794986, HPA041478: AB_10794668" "unprognostic (6.02e-2)" "unprognostic (1.81e-1)" "unprognostic (1.59e-3)" "prognostic favorable (1.68e-4)" "unprognostic (4.41e-1)" "unprognostic (1.06e-1)" "unprognostic (3.78e-3)" "unprognostic (1.10e-1)" "unprognostic (1.82e-1)" "unprognostic (1.25e-1)" "unprognostic (5.69e-2)" "unprognostic (6.58e-2)" "unprognostic (1.67e-1)" "unprognostic (2.44e-1)" "unprognostic (3.31e-2)" "unprognostic (2.23e-1)" "unprognostic (9.60e-2)" 12.8 12.8 8.4 4.6 8.3 3.5 14.9 22.0 11.5 23.2 13.6 28.6 3.9 21.2 5.6 8.6 30.7 3.6 13.2 8.2 8.6 26.6 11.6 14.7 2.2 9.9 10.9 21.2 67.2 16.0 25.6 3.3 8.4 20.6 2.7 8.5 13.7 9.2 9.5 12.1 11.1 4.4 10.0 11.9 15.9 41.1 9.1 4.7 22.3 1.6 2.5 21.5 14.2 8.5 11.1 7.5 17.2 8.0 5.6 5.8 8.5 8.5 5.1 6.7 8.1 5.5 16.5 4.1 14.3 5.3 0.0 12.7 4.5 10.2 8.2 6.5 10.2 4.1 25.7 13.1 9.1 7.4 5.4 5.1 7.3 9.1 8.2 15.4 5.5 13.3 6.9 2.5 3.5 5.7 8.2 30.9 8.2 11.5 3.0 28.5 1.8 31.3 7.2 1.1 17.4 18.9 18.2 1.8 9.7 3.9 15.8 10.5 14.3 8.1 11.4 15.2 0.1 19.1 9.2 4.5 12.3 10.8 2.5 0.0 0.4 0.0 0.1 0.1 0.4 0.2 0.3 0.2 0.1 0.0 0.2 0.3 0.9 0.2 0.2 1.3 0.0 0.1 8.4 8.3 22.0 11.5 8.2 8.6 9.9 10.9 8.4 10.0 9.1 8.5 8.8 22.4 14.4 8.8 1.7 6.9 5.9 6.2 4.0 3.6 10.4 11.2 5.5 10.0 4.0 9.2 4.2 3.1 1.5 4.4 1.9 13.1 34.2 38.3 10.5 8.6 13.2 2.1 2.1 10.7 2.4 7.5 1.5 9.5 1.3 7.4 10.4 26.4 4.7 3.3 2.2 6.0 2.0 3.2 4.3 20.6 13.1 2.6 5.4 0.0 3.0 8.8 0.0 2.5 1.7 9.5 1.4 14.3 2.6 6.0 1.8 7.3 42.5 10.5 6.6 9.1 8.0 37.0 7.9 1.2 5.3 3.4 1.9 11.6 4.9 4.4 ENO3 ENSG00000108515 "Enolase 3" P13929 17 4948092-4957131 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Lyase "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 26 "skeletal muscle: 14758.3;tongue: 10771.0" "Group enriched" "Detected in many" 5 "Cardiomyocytes: 582.2;Skeletal myocytes: 248.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 263.8;HeLa: 120.0;HMC-1: 115.1;RH-30: 170.2;RPMI-8226: 96.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000793, HPA068284, HPA068721" Enhanced Supported "Plasma membrane,Cytosol" Yes No 86000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA000793: AB_1078742, HPA068284: , HPA068721: AB_2732119" "unprognostic (7.35e-2)" "unprognostic (5.25e-2)" "prognostic unfavorable (7.33e-4)" "unprognostic (1.57e-1)" "unprognostic (1.29e-1)" "unprognostic (5.86e-2)" "unprognostic (5.68e-2)" "unprognostic (2.08e-2)" "unprognostic (8.12e-2)" "unprognostic (1.42e-1)" "unprognostic (6.04e-3)" "unprognostic (2.21e-2)" "unprognostic (4.63e-2)" "unprognostic (5.34e-2)" "unprognostic (3.48e-1)" "unprognostic (2.15e-1)" "unprognostic (4.50e-2)" 7.8 5.5 3.8 15.6 3.9 20.4 8.0 7.1 4.3 6.6 5.0 8.0 20.1 7.2 7.1 173.8 7.4 2.6 499.8 3.5 3.7 10.3 108.0 8.6 13.0 4.3 5.0 6.0 5.5 4.0 7.9 6.3 4.6 47.3 3.0 5.0 116.8 3.1 14758.3 8.3 15.6 2.8 4.1 16.9 10.1 9.3 4.3 5.8 10.3 10771.0 4.9 5.6 5.0 4.9 12.0 25.5 11.3 10.7 9.1 2.2 27.6 21.0 2.7 1.5 1.3 12.8 8.1 21.9 25.8 1.9 3.5 15.4 3.8 1.9 1.0 263.8 24.3 21.9 120.0 18.9 3.7 6.8 115.1 14.4 3.8 2.1 4.1 9.8 1.4 24.8 10.2 39.0 4.9 6.6 7.9 26.5 14.8 3.3 10.6 34.6 170.2 96.9 3.1 7.9 7.1 27.1 13.6 11.4 14.7 7.6 10.2 7.0 6.5 12.1 21.3 5.4 16.0 27.6 16.8 18.2 6.7 20.8 12.2 31.4 28.5 50.4 36.8 41.5 24.8 24.5 30.8 34.4 37.6 20.1 20.0 32.2 34.4 34.9 47.6 29.9 43.2 83.6 3.8 3.9 7.1 4.3 3.5 3.7 4.3 5.0 4.6 4.1 4.3 4.9 1.2 0.0 1.8 2.3 2.7 2.0 1.2 2.1 4.0 6.6 3.0 3.0 582.2 0.0 2.2 5.5 4.2 5.4 3.2 2.9 0.0 1.5 1.8 0.9 1.6 7.3 0.0 3.8 0.2 0.8 3.8 17.3 4.6 2.2 8.2 2.4 2.2 56.2 4.5 3.3 0.2 2.2 2.0 3.5 6.7 3.7 0.3 4.3 1.8 0.0 78.3 1.9 4.1 1.0 0.5 1.8 1.9 0.4 2.3 1.2 6.6 9.5 0.3 2.5 6.6 248.4 55.8 7.9 7.5 2.1 1.8 3.3 4.5 1.1 2.6 0.8 EPB41 "4.1R, EL1" ENSG00000159023 "Erythrocyte membrane protein band 4.1" P11171 1 28887091-29120046 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell cycle, Cell division, Mitosis, Transport" "Actin-binding, Calmodulin-binding" "Elliptocytosis, Hereditary hemolytic anemia, Pyropoikilocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 80.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 151.6;Cone photoreceptor cells: 137.6;Erythroid cells: 187.1;Rod photoreceptor cells: 171.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 42.2" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 136.3;K-562: 136.5" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 8 "cerebellum: 105.6" "HPA028076, HPA028096, HPA028412, HPA028414" Supported Supported "Nuclear bodies,Plasma membrane,Cell Junctions,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes No 1100000 "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane, Cell Junctions" "Nuclear bodies, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA028076: AB_2672476, HPA028096: , HPA028412: AB_2672592, HPA028414: AB_10601366" "unprognostic (2.16e-1)" "unprognostic (1.96e-1)" "unprognostic (8.92e-3)" "prognostic unfavorable (4.58e-4)" "unprognostic (5.00e-2)" "prognostic favorable (5.87e-4)" "unprognostic (5.01e-3)" "unprognostic (5.40e-3)" "unprognostic (2.52e-2)" "unprognostic (6.65e-2)" "unprognostic (7.81e-2)" "unprognostic (1.42e-2)" "prognostic unfavorable (1.75e-6)" "unprognostic (2.66e-2)" "unprognostic (2.42e-1)" "unprognostic (1.22e-1)" "unprognostic (6.67e-2)" 11.0 10.2 1.8 21.9 18.3 63.3 14.1 42.2 6.0 14.5 4.9 23.6 17.7 10.2 5.3 16.6 6.3 15.0 9.7 1.2 4.7 12.7 21.7 15.1 37.4 8.2 5.6 16.3 18.8 15.5 4.7 7.2 8.5 15.0 23.1 80.0 19.1 9.1 15.9 15.3 23.3 9.9 3.5 22.9 27.0 10.4 4.7 69.0 15.2 13.8 37.0 15.5 1.9 3.0 27.0 6.9 62.3 29.4 5.2 0.8 19.5 6.9 10.1 8.4 10.5 16.8 31.2 49.1 17.2 9.2 13.5 11.9 78.7 6.6 8.6 86.4 23.8 136.3 19.7 28.6 10.1 45.8 88.2 1.7 18.4 8.2 13.8 19.9 14.1 73.5 136.5 36.2 0.1 8.8 72.3 30.4 62.0 44.1 10.0 110.9 28.2 68.3 7.7 33.3 78.0 60.5 19.7 19.2 43.3 21.7 14.7 18.2 1.2 0.3 13.3 12.9 13.4 52.5 72.4 85.2 12.1 47.8 6.8 33.3 3.2 21.4 12.9 1.1 15.4 17.2 18.3 14.1 4.4 13.6 22.1 12.7 44.2 10.9 1.5 4.4 28.9 15.3 1.8 18.3 42.2 6.0 1.2 4.7 8.2 5.6 8.5 3.5 4.7 3.0 25.3 19.2 71.7 20.2 58.2 10.5 8.6 7.8 15.4 151.6 20.0 12.2 21.5 20.0 16.8 16.5 137.6 2.4 75.3 26.5 17.6 17.1 16.4 11.3 4.1 15.1 41.6 187.1 76.3 18.7 4.2 7.9 29.6 29.1 24.1 24.9 17.5 30.0 7.1 21.9 61.7 29.0 16.2 23.7 9.0 22.7 2.1 32.4 0.0 78.7 29.3 15.7 85.5 7.5 4.8 28.6 20.3 2.2 46.7 12.2 32.8 13.4 15.2 171.4 13.1 2.8 8.5 39.3 55.7 14.9 16.8 4.1 71.6 4.2 33.0 12.6 ERCC6 "ARMD5, CKN2, CSB, RAD26" ENSG00000225830 "ERCC excision repair 6, chromatin remodeling factor" "P0DP91, Q03468" 10 49454168-49539538 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Neurogenesis, Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase" "Age-related macular degeneration, Cancer-related genes, Cataract, Cockayne syndrome, Deafness, Disease variant, Dwarfism, Mental retardation, Premature ovarian failure, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 53.8;hTERT-RPE1: 123.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071297 Approved "Nucleoplasm,Nuclear bodies" Yes No "Cluster 6: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nuclear bodies" "HPA071297: AB_2732177" "unprognostic (1.92e-2)" "unprognostic (1.85e-1)" "unprognostic (9.79e-3)" "unprognostic (7.26e-2)" "unprognostic (5.45e-2)" "unprognostic (2.95e-2)" "unprognostic (3.03e-2)" "unprognostic (2.99e-2)" "unprognostic (1.71e-2)" "unprognostic (1.13e-1)" "unprognostic (1.80e-1)" "unprognostic (4.57e-2)" "unprognostic (1.04e-1)" "unprognostic (8.61e-2)" "unprognostic (4.75e-2)" "unprognostic (1.73e-1)" "unprognostic (7.05e-2)" 2.7 2.1 1.6 1.9 1.5 4.6 3.8 3.0 2.3 3.1 7.7 2.4 2.0 3.0 1.5 3.8 2.9 2.7 3.4 1.2 1.1 3.2 3.3 2.7 2.9 2.4 1.9 4.5 3.1 5.9 2.8 3.4 2.1 3.3 2.7 3.1 3.2 2.2 3.5 4.6 2.5 2.3 2.2 2.9 2.4 3.1 2.1 3.3 5.1 3.6 3.4 2.6 3.3 1.9 11.2 5.5 4.1 2.1 6.6 10.5 3.4 21.2 27.1 14.1 9.9 6.2 5.6 4.9 3.7 18.7 6.7 9.5 6.3 16.6 13.5 8.4 4.1 3.9 21.7 3.4 3.9 5.0 3.7 4.3 17.2 12.9 53.8 123.4 19.8 2.9 6.8 0.8 16.8 8.3 3.4 2.0 4.0 3.5 10.2 2.3 5.8 2.6 4.1 7.1 5.9 4.7 15.4 3.6 8.2 9.4 7.1 2.7 38.9 7.0 5.5 8.6 5.2 3.3 4.5 4.1 7.3 5.0 5.1 13.1 3.0 7.5 4.1 2.6 3.0 6.8 2.3 2.2 3.9 5.2 2.8 1.4 7.2 1.2 5.3 2.2 3.1 1.8 1.6 1.5 3.0 2.3 1.2 1.1 2.4 1.9 2.1 2.2 2.1 1.9 6.9 16.0 13.2 14.7 6.0 3.6 1.4 1.5 5.2 0.0 7.1 7.1 7.1 5.7 8.2 9.2 0.0 2.5 10.9 4.8 5.9 5.2 11.3 8.1 8.7 5.1 1.2 1.3 24.3 6.0 2.1 4.9 2.0 10.1 7.6 8.9 5.3 4.3 2.6 0.0 21.7 5.3 0.0 4.4 2.6 15.3 2.8 8.0 1.8 23.4 11.2 0.0 4.1 17.6 16.6 5.2 2.6 2.2 3.6 2.5 5.0 3.6 9.0 0.0 6.6 4.4 4.2 5.3 5.0 3.5 4.1 1.8 7.4 11.4 2.8 1.9 ERI3 "FLJ22943, PINT1, PRNPIP" ENSG00000117419 "ERI1 exoribonuclease family member 3" O43414 1 44221070-44355260 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 943.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027147, HPA029895" Approved Approved Nucleoplasm,Cytosol Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA027147: AB_1855725, HPA029895: AB_2673239" "unprognostic (1.31e-1)" "unprognostic (2.39e-2)" "unprognostic (3.26e-1)" "prognostic unfavorable (1.18e-4)" "unprognostic (5.94e-2)" "unprognostic (6.21e-2)" "prognostic unfavorable (2.04e-6)" "unprognostic (6.48e-2)" "unprognostic (2.67e-1)" "unprognostic (6.70e-3)" "unprognostic (5.30e-2)" "unprognostic (2.49e-1)" "unprognostic (1.49e-2)" "unprognostic (2.07e-1)" "unprognostic (7.47e-2)" "unprognostic (1.08e-1)" "unprognostic (2.07e-3)" 31.1 34.8 105.3 15.5 105.9 24.6 30.5 92.0 140.3 30.1 92.2 34.4 20.6 33.3 34.2 27.9 37.2 20.5 51.7 111.9 98.7 59.8 41.8 25.6 19.3 99.4 108.1 32.4 35.0 45.2 45.1 23.3 122.2 38.8 23.2 22.4 27.8 25.2 77.2 36.1 22.7 28.6 97.2 26.4 28.9 63.3 105.7 24.1 31.2 60.2 20.4 32.2 27.2 103.4 73.6 56.5 69.3 77.7 44.9 55.5 46.0 44.0 61.4 82.1 75.1 37.8 78.3 52.3 76.4 58.7 42.2 41.2 62.6 80.6 55.9 56.9 115.8 60.0 90.2 52.0 67.9 59.3 32.8 57.9 76.9 66.2 91.3 61.0 57.3 59.5 56.4 43.9 55.2 51.2 68.7 57.0 82.2 72.2 83.7 62.6 62.4 75.3 65.2 38.9 120.5 54.9 52.5 71.3 87.7 55.1 46.6 50.1 34.1 54.3 56.5 60.7 72.0 37.7 50.1 56.4 67.7 52.4 70.4 17.6 25.8 15.8 25.5 36.4 27.2 30.8 21.1 24.5 40.3 30.9 24.8 26.0 2.4 26.1 37.3 30.3 29.4 26.2 105.3 105.9 92.0 140.3 111.9 98.7 99.4 108.1 122.2 97.2 105.7 103.4 35.4 25.6 16.5 74.4 26.2 31.6 36.5 64.7 27.3 22.6 36.2 51.3 15.1 15.7 26.2 29.5 2.1 93.2 19.3 31.2 97.8 56.9 202.7 35.3 30.7 27.4 118.3 26.5 36.7 62.5 85.9 39.8 25.0 23.1 15.2 62.8 18.9 22.3 45.0 25.2 34.0 99.1 46.8 19.2 27.2 943.6 36.4 20.1 48.0 38.4 27.9 42.6 15.5 66.4 54.5 37.7 22.2 36.5 28.3 51.0 17.0 167.3 20.4 16.4 6.6 28.5 52.0 68.0 51.4 29.4 34.5 61.6 20.2 54.0 37.1 30.7 ESCO2 "EFO2, RBS" ENSG00000171320 "Establishment of sister chromatid cohesion N-acetyltransferase 2" Q56NI9 8 27771949-27812640 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;intestine: 11.0;lymphoid tissue: 8.5;testis: 5.7" "Group enriched" "Detected in many" 4 "Erythroid cells: 44.6;Spermatocytes: 62.0;Spermatogonia: 80.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.3" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA027243, HPA053679" Supported "Nucleoplasm,Golgi apparatus,Cell Junctions" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Golgi apparatus" "Cell Junctions" "HPA027243: AB_2672175, HPA053679: AB_2682227" "unprognostic (7.86e-2)" "unprognostic (1.50e-2)" "prognostic favorable (1.04e-4)" "unprognostic (5.13e-3)" "unprognostic (9.50e-2)" "unprognostic (8.67e-3)" "unprognostic (7.30e-4)" "unprognostic (5.24e-3)" "unprognostic (2.24e-2)" "unprognostic (2.54e-2)" "unprognostic (7.51e-4)" "unprognostic (2.23e-1)" "unprognostic (1.65e-14)" "unprognostic (6.65e-3)" "unprognostic (5.32e-1)" "unprognostic (5.85e-2)" "unprognostic (4.06e-1)" 0.5 0.4 0.0 2.7 0.2 6.0 1.2 0.4 0.2 0.5 0.0 3.7 11.0 0.6 0.0 2.4 0.2 0.6 0.2 0.0 0.0 0.1 0.7 0.4 4.6 0.0 0.0 0.1 1.0 0.3 0.0 1.1 0.1 0.3 4.3 0.5 0.3 0.1 0.0 1.1 7.9 0.7 0.0 0.8 2.5 5.7 0.0 8.5 0.3 0.2 5.7 0.8 0.5 0.2 54.6 39.9 17.9 22.0 2.3 3.9 10.2 31.6 12.9 27.8 32.5 14.2 10.7 21.0 16.6 8.3 24.7 29.2 22.0 8.5 43.6 15.8 9.2 24.4 16.2 15.3 0.3 12.5 21.4 0.7 0.9 17.0 4.2 3.0 11.6 15.2 20.0 30.0 17.7 10.5 49.8 5.9 12.2 29.9 13.4 21.7 53.0 14.8 9.6 31.9 8.0 11.7 15.5 19.6 7.9 6.5 13.2 14.1 5.2 17.9 37.0 36.2 25.7 4.0 11.1 25.2 10.2 20.5 25.2 0.0 0.2 0.1 0.0 0.4 0.0 0.4 0.2 0.2 0.6 0.0 0.1 0.1 0.2 0.3 0.1 0.0 1.3 0.3 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 4.7 0.0 2.4 2.3 0.6 2.1 1.8 1.2 1.5 1.7 1.2 0.0 3.3 0.0 4.2 4.6 1.3 8.2 0.0 0.4 5.4 1.3 2.6 1.0 1.2 44.6 0.3 0.0 6.6 3.2 5.6 3.1 1.3 11.4 1.4 1.5 5.4 0.0 0.4 4.4 2.0 2.5 3.5 0.8 1.8 3.2 0.0 1.0 0.5 0.1 4.1 1.0 0.9 0.1 1.5 0.0 11.5 0.6 15.1 0.1 1.6 2.0 6.6 0.8 2.3 62.0 80.0 6.8 0.6 1.0 3.1 1.8 8.0 1.4 ESRRA "ERR1, ERRa, ERRalpha, ESRL1, NR3B1" ENSG00000173153 "Estrogen related receptor alpha" P11474 11 64305497-64316743 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 195.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 159.2;Hepatocytes: 266.3;Proximal enterocytes: 199.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053785, HPA077297" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Microtubules,Cytokinetic bridge" Yes No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Nucleoli fibrillar center, Microtubules" "Cytokinetic bridge" "HPA053785: AB_2682260, HPA077297: " "unprognostic (7.63e-2)" "unprognostic (1.51e-1)" "unprognostic (1.04e-1)" "unprognostic (1.28e-2)" "unprognostic (3.08e-1)" "unprognostic (7.24e-2)" "unprognostic (1.07e-1)" "unprognostic (2.97e-1)" "unprognostic (2.98e-1)" "unprognostic (3.52e-2)" "unprognostic (2.50e-2)" "unprognostic (1.03e-1)" "prognostic favorable (1.34e-7)" "unprognostic (3.43e-3)" "unprognostic (3.19e-2)" "unprognostic (2.38e-2)" "unprognostic (7.20e-2)" 27.3 35.5 25.5 15.8 29.8 16.3 23.6 36.4 31.4 17.5 33.6 67.6 81.8 15.5 4.7 62.7 14.6 10.2 154.9 23.5 31.6 70.3 91.5 30.9 11.0 30.9 31.7 8.1 56.3 23.9 15.9 15.4 29.8 26.4 22.9 5.1 48.5 12.6 195.3 35.9 65.4 7.1 26.6 32.0 52.4 8.4 37.5 8.4 28.3 88.8 12.4 31.0 28.8 23.7 25.9 40.2 9.8 23.6 13.0 12.7 54.2 25.0 11.9 9.2 9.0 37.4 30.3 34.9 45.1 12.8 23.7 66.0 16.9 33.0 3.5 23.0 21.0 22.9 51.7 30.1 18.0 39.3 55.3 17.4 49.8 20.7 27.0 12.8 12.8 18.1 37.9 18.7 15.3 57.9 19.4 55.9 27.9 30.4 74.4 20.4 19.7 79.6 31.1 52.4 20.6 26.2 12.8 81.2 83.8 5.5 25.8 38.2 28.9 16.6 20.4 47.4 25.6 28.6 25.5 23.6 26.9 38.2 13.4 0.2 2.9 4.8 2.7 5.4 2.6 1.7 2.3 1.9 2.7 2.3 2.3 3.3 5.3 1.8 5.1 2.1 3.6 1.7 25.5 29.8 36.4 31.4 23.5 31.6 30.9 31.7 29.8 26.6 37.5 23.7 20.8 9.6 22.7 21.2 14.7 18.6 41.0 29.7 18.8 28.8 30.9 24.3 9.2 100.1 21.3 20.2 33.3 103.8 20.9 159.2 54.8 51.3 3.4 18.7 17.4 15.3 37.8 19.4 13.6 80.2 61.3 12.4 39.8 20.3 7.6 9.3 35.0 266.3 33.6 33.7 16.6 82.5 28.5 82.7 11.7 1.1 6.5 22.2 17.8 11.2 28.8 20.1 27.8 9.0 6.4 81.1 103.1 12.0 8.2 42.8 199.7 82.2 19.8 20.4 13.1 18.7 21.7 3.5 7.1 26.3 18.5 134.2 14.5 22.2 113.7 65.0 ETNPPL AGXT2L1 ENSG00000164089 "Ethanolamine-phosphate phospho-lyase" Q8TBG4 4 108742048-108763054 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 155.6;liver: 191.1" "Cell type enriched" "Detected in some" 8 "Astrocytes: 219.4" "Group enriched" "Detected in some" 23 "glioma: 7.9;liver cancer: 21.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 5.7;Hep G2: 2.3;NTERA-2: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044546, HPA072938" Supported Approved Nucleoplasm Yes NA "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA044546: AB_10962867, HPA072938: AB_2686560" "unprognostic (5.20e-3)" "unprognostic (1.33e-1)" "unprognostic (3.93e-1)" "prognostic favorable (9.52e-5)" "unprognostic (5.93e-3)" "unprognostic (3.91e-2)" "unprognostic (2.82e-1)" "unprognostic (6.32e-2)" "unprognostic (2.70e-2)" "unprognostic (1.30e-1)" "unprognostic (3.40e-2)" "unprognostic (1.93e-1)" "unprognostic (1.59e-1)" "unprognostic (1.42e-2)" "unprognostic (9.48e-2)" 0.3 5.5 155.6 0.1 155.6 0.0 0.1 98.4 144.3 0.1 47.4 0.0 0.2 0.3 0.0 0.1 0.0 0.2 10.6 124.4 145.8 9.1 191.1 0.1 0.0 100.7 118.1 0.1 0.0 2.9 1.9 0.0 110.3 0.0 0.0 1.7 34.4 0.1 2.4 0.0 0.0 0.0 101.2 0.7 18.3 0.5 119.8 0.1 1.1 1.5 0.0 0.0 0.0 101.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.0 5.7 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 155.6 155.6 98.4 144.3 124.4 145.8 100.7 118.1 110.3 101.2 119.8 101.3 0.0 0.0 0.0 219.4 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 14.2 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.4 0.0 0.0 0.4 0.0 0.0 0.5 1.5 0.4 0.0 0.0 0.7 26.8 0.0 0.0 0.6 0.0 0.0 1.6 0.0 1.7 0.0 0.0 0.0 7.5 0.0 8.5 0.0 1.5 0.7 0.0 0.0 0.0 0.1 0.0 0.0 7.9 0.0 0.2 0.0 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 ETV4 "E1A-F, E1AF, PEA3" ENSG00000175832 "ETS variant transcription factor 4" P43268 17 43527844-43579620 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 23.3;Cholangiocytes: 17.2;Distal tubular cells: 17.6;Enteroendocrine cells: 14.9;Extravillous trophoblasts: 19.8;Syncytiotrophoblasts: 14.9" "Cancer enhanced" "Detected in all" "testis cancer: 80.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 177.7;Hep G2: 173.0;SK-MEL-30: 197.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA005768 Approved Supported "Nucleoli rim,Mitotic chromosome" Yes No "Cluster 24: Salivary gland - Salivary secretion" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoli rim" "Mitotic chromosome" "HPA005768: AB_1848294" "unprognostic (2.32e-1)" "unprognostic (7.33e-2)" "unprognostic (2.14e-1)" "unprognostic (2.51e-1)" "unprognostic (1.97e-2)" "unprognostic (3.14e-3)" "prognostic unfavorable (2.48e-4)" "unprognostic (1.58e-2)" "unprognostic (5.34e-2)" "unprognostic (8.13e-2)" "unprognostic (7.05e-2)" "unprognostic (3.01e-1)" "unprognostic (7.79e-2)" "unprognostic (2.03e-1)" "unprognostic (7.08e-2)" "prognostic favorable (7.60e-4)" "unprognostic (1.69e-1)" 0.5 2.4 1.2 1.0 1.6 0.0 7.0 0.8 2.2 3.6 0.0 2.0 6.1 2.4 1.0 9.2 2.5 6.4 3.1 1.3 0.8 5.4 1.2 2.2 0.6 1.0 0.9 0.4 7.8 7.9 14.7 5.2 1.4 4.5 1.7 3.0 4.6 3.6 1.3 6.4 4.2 1.4 0.3 0.4 3.8 1.2 0.7 0.3 6.9 2.5 4.8 2.1 5.3 0.9 24.5 67.0 80.4 177.7 3.1 20.1 17.9 7.9 21.1 14.9 15.2 38.1 33.9 0.1 4.3 4.1 36.6 43.6 2.7 40.2 13.2 0.8 0.5 2.3 10.7 173.0 4.3 47.0 20.9 3.6 1.4 56.8 35.0 16.8 32.1 0.3 48.9 0.1 31.0 9.8 0.2 82.9 116.9 123.1 110.9 99.8 9.8 58.9 33.0 17.3 0.1 71.4 2.1 4.5 197.0 43.8 0.8 13.9 15.1 10.6 52.0 15.7 22.1 7.3 47.8 0.1 18.9 8.9 63.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 1.6 0.8 2.2 1.3 0.8 1.0 0.9 1.4 0.3 0.7 0.9 0.2 0.0 0.0 1.3 0.0 1.9 2.5 3.6 23.3 3.2 10.4 12.3 1.1 17.2 2.4 0.0 0.0 2.3 0.1 1.1 17.6 6.5 3.1 0.7 0.3 1.5 14.9 0.0 1.6 1.0 19.8 1.9 3.1 1.6 0.0 0.2 0.7 0.0 0.8 0.0 1.0 4.0 2.0 0.3 0.3 6.0 0.3 0.2 3.6 1.0 0.0 10.9 0.0 1.0 0.0 3.7 3.3 0.4 0.0 0.9 1.9 0.1 1.0 0.3 0.0 2.1 1.7 0.0 1.3 3.6 1.1 14.9 0.3 0.1 7.7 4.3 EVC2 LBN ENSG00000173040 "EvC ciliary complex subunit 2" Q86UK5 4 5542772-5709548 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ciliopathy, Disease variant, Dwarfism, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 17.6;Basal squamous epithelial cells: 12.0;Fibroblasts: 8.9;Leydig cells: 11.5;Skeletal myocytes: 14.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 9.7;HHSteC: 13.0;hTERT-HME1: 10.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040910, HPA048122" Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Microtubules, Cytokinetic bridge" "Nucleoplasm, Cytosol" "HPA040910: AB_2677195, HPA048122: AB_2680272" "unprognostic (6.56e-2)" "unprognostic (6.74e-2)" "unprognostic (5.10e-2)" "unprognostic (2.25e-1)" "unprognostic (8.23e-3)" "unprognostic (2.80e-1)" "unprognostic (2.05e-2)" "unprognostic (1.22e-2)" "unprognostic (1.71e-1)" "unprognostic (1.28e-1)" "unprognostic (8.57e-2)" "unprognostic (9.37e-2)" "prognostic favorable (1.58e-4)" "unprognostic (2.51e-2)" "unprognostic (3.14e-1)" "unprognostic (5.61e-2)" "unprognostic (6.29e-5)" 4.8 0.7 1.3 1.5 1.4 0.1 3.6 1.2 1.1 6.0 2.3 3.7 0.6 4.7 1.7 2.2 4.7 2.7 3.1 1.3 1.4 2.6 0.7 2.1 1.9 1.6 1.5 7.8 1.7 3.1 1.1 1.3 1.2 3.2 0.6 0.3 2.8 2.0 1.1 3.8 2.0 2.3 1.4 1.0 2.1 1.6 1.5 1.0 3.8 1.9 1.7 4.1 4.4 1.3 0.0 2.7 0.0 6.6 8.4 9.3 0.0 4.1 9.7 3.6 6.0 0.0 0.0 5.2 0.0 3.3 2.0 2.8 0.0 1.7 3.4 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 5.9 4.6 4.6 10.6 0.0 3.9 0.0 0.0 0.2 5.3 0.0 0.0 0.0 3.9 0.0 0.0 8.6 8.2 0.0 0.4 0.0 0.4 0.6 0.0 0.0 0.0 1.6 0.0 0.5 6.7 0.0 0.0 2.4 0.0 4.1 4.7 1.2 2.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 1.4 1.2 1.1 1.3 1.4 1.6 1.5 1.2 1.4 1.5 1.3 0.6 0.0 0.5 17.6 0.8 2.2 4.9 2.3 12.0 0.0 0.9 2.2 1.0 1.5 1.3 0.0 0.0 8.3 1.7 0.0 0.0 1.9 2.2 0.7 5.6 1.2 0.0 0.4 0.3 0.5 0.3 8.9 0.5 1.7 2.5 4.7 1.4 0.1 0.5 0.0 0.3 0.0 0.0 0.3 1.2 0.9 11.5 0.8 0.0 6.5 0.0 1.9 1.0 1.0 0.3 0.6 0.0 7.9 1.7 2.8 0.0 0.9 1.0 0.1 0.0 14.7 3.2 1.8 2.1 4.4 0.9 1.4 2.8 3.4 0.0 1.4 EXOSC8 "bA421P11.3, CIP3, EAP2, OIP2, p9, RRP43, Rrp43p" ENSG00000120699 "Exosome component 8" Q96B26 13 36998816-37009614 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "rRNA processing" RNA-binding "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 163.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034240, HPA039702, HPA043942, HPA075230" Uncertain Supported "Nucleoli fibrillar center,Mitotic chromosome,Vesicles" Yes NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli fibrillar center, Mitotic chromosome, Vesicles" "CAB034240: AB_2101977, HPA039702: AB_2676634, HPA043942: AB_2678742, HPA075230: " "unprognostic (8.67e-2)" "unprognostic (9.39e-2)" "unprognostic (5.77e-2)" "unprognostic (1.03e-1)" "unprognostic (2.58e-2)" "unprognostic (1.24e-2)" "unprognostic (1.02e-1)" "unprognostic (4.01e-2)" "unprognostic (3.24e-3)" "unprognostic (2.45e-2)" "unprognostic (2.35e-2)" "unprognostic (7.32e-3)" "prognostic unfavorable (8.39e-7)" "unprognostic (9.58e-3)" "unprognostic (7.42e-2)" "unprognostic (1.10e-1)" "unprognostic (4.51e-1)" 15.0 14.2 16.6 19.1 17.6 27.5 18.8 17.9 24.3 16.8 16.6 17.0 12.6 14.2 14.4 18.2 16.8 8.4 19.4 16.9 17.8 17.9 19.8 13.5 21.2 17.5 17.1 16.4 13.9 11.6 10.8 15.6 18.1 14.2 19.0 15.3 11.3 13.2 24.2 16.6 14.0 16.6 17.3 17.5 15.3 27.8 17.0 31.5 12.3 24.8 25.1 16.2 14.7 19.7 47.5 33.5 97.7 66.4 28.4 30.1 73.8 68.9 48.8 93.2 74.2 72.7 93.6 65.1 29.8 38.2 91.4 64.7 92.7 67.1 111.5 96.3 73.9 174.8 34.2 87.4 37.0 148.3 58.9 17.4 51.3 62.6 100.2 24.1 72.8 93.6 86.6 41.3 66.4 59.1 78.6 116.6 101.4 113.2 44.0 48.5 98.6 53.5 51.1 30.8 23.8 46.1 38.1 44.5 65.3 51.1 35.4 117.6 37.2 35.5 49.1 42.9 95.5 23.3 29.4 135.7 56.0 104.1 66.8 28.9 29.8 23.5 42.8 39.6 44.8 66.0 54.1 50.5 33.9 57.2 67.1 62.7 6.0 46.2 41.7 54.8 54.6 52.4 16.6 17.6 17.9 24.3 16.9 17.8 17.5 17.1 18.1 17.3 17.0 19.7 43.5 32.1 38.9 15.7 40.1 36.1 51.6 109.6 25.0 20.8 25.0 50.0 50.2 18.6 69.5 11.0 8.4 86.8 46.8 13.1 56.7 58.1 115.7 21.5 31.4 39.4 13.2 57.9 7.0 52.1 92.3 41.8 19.4 20.6 103.6 46.2 18.5 17.4 46.8 28.6 8.6 19.1 79.3 13.6 34.2 54.6 40.7 26.0 26.6 10.3 32.6 27.1 35.0 17.1 22.0 36.1 16.4 36.5 38.8 29.0 18.0 26.6 53.4 32.0 26.3 38.8 52.1 163.3 85.9 29.0 36.2 67.0 38.7 42.7 30.2 37.7 EYA3 DKFZp686C132 ENSG00000158161 "EYA transcriptional coactivator and phosphatase 3" Q99504 1 27970344-28088637 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 80.2;Oligodendrocytes: 80.5;Spermatocytes: 98.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052432, HPA062889" Uncertain Supported Nucleoplasm Yes No "Cluster 49: Eosinophils - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "HPA052432: AB_2681831, HPA062889: AB_2684895" "unprognostic (3.57e-1)" "unprognostic (2.61e-1)" "unprognostic (2.85e-1)" "unprognostic (8.74e-2)" "unprognostic (1.39e-1)" "prognostic favorable (5.11e-4)" "unprognostic (1.39e-3)" "unprognostic (2.21e-1)" "unprognostic (4.81e-2)" "unprognostic (1.00e-1)" "unprognostic (9.13e-2)" "unprognostic (8.98e-2)" "prognostic favorable (3.15e-6)" "unprognostic (5.17e-2)" "unprognostic (2.79e-1)" "unprognostic (7.60e-2)" "unprognostic (6.11e-2)" 4.7 4.8 7.4 8.2 7.0 5.2 7.1 8.8 7.9 7.4 9.6 5.7 5.9 6.1 6.4 9.9 6.2 4.3 6.4 6.5 7.6 11.6 6.0 5.9 9.4 7.1 7.1 6.4 6.5 8.3 7.6 7.7 7.2 6.1 6.2 10.5 5.6 5.4 7.1 9.0 6.3 5.5 6.4 7.2 5.5 11.4 7.6 9.4 9.3 8.3 14.4 7.1 6.1 7.9 16.3 6.6 13.1 9.7 14.9 11.6 7.3 11.8 11.0 13.2 12.9 6.4 9.5 25.5 12.3 7.8 4.9 15.3 24.4 9.5 15.6 13.4 13.5 28.2 14.4 11.6 8.8 27.9 25.2 7.0 8.3 14.6 9.7 11.3 17.0 9.0 26.9 9.6 11.9 7.0 18.0 18.5 27.5 12.6 8.6 13.2 24.9 16.8 15.3 8.8 14.9 8.2 12.6 7.6 11.0 10.5 6.2 7.3 16.6 15.9 8.4 15.1 9.4 13.9 15.2 22.0 11.5 26.7 7.0 5.7 6.8 7.3 7.5 6.9 6.7 5.2 5.8 5.4 8.3 4.6 4.9 5.6 6.4 7.1 6.1 5.1 5.4 1.9 7.4 7.0 8.8 7.9 6.5 7.6 7.1 7.1 7.2 6.4 7.6 7.9 12.6 9.6 10.8 46.4 17.5 17.8 11.3 10.0 9.6 18.3 12.0 7.1 9.2 12.8 7.9 25.8 16.7 13.0 10.6 8.2 15.6 13.5 80.2 13.6 13.2 12.9 20.4 9.9 66.0 8.9 14.4 11.6 16.8 15.3 12.0 15.8 14.6 8.7 9.7 18.5 58.8 9.1 12.2 13.3 46.1 39.1 10.2 14.6 12.4 39.4 12.9 8.1 10.3 45.2 80.5 14.5 10.9 6.0 13.7 12.0 13.8 18.0 5.7 20.6 13.1 11.1 8.4 98.7 50.6 10.7 22.9 10.9 15.8 9.6 10.5 11.7 FAM110A "bA371L19.3, C20orf55" ENSG00000125898 "Family with sequence similarity 110 member A" Q9BQ89 20 833715-857463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 71.2" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 71.7;Extravillous trophoblasts: 138.2;Langerhans cells: 74.2;Macrophages: 70.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "basophil: 543.5;eosinophil: 163.4;intermediate monocyte: 160.6;non-classical monocyte: 248.6" "Group enriched" "Detected in all" 9 "granulocytes: 543.5;monocytes: 248.6" "Cell line enhanced" "Detected in all" "SK-BR-3: 84.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB034110, HPA069240" Uncertain Uncertain Nucleoplasm,Vesicles,Cytosol Yes Yes "Cluster 10: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Vesicles" Cytosol "CAB034110: AB_1562838, HPA069240: AB_2686103" "unprognostic (6.33e-2)" "unprognostic (2.53e-2)" "unprognostic (1.57e-2)" "unprognostic (3.43e-2)" "unprognostic (1.81e-1)" "unprognostic (3.37e-2)" "unprognostic (4.90e-3)" "unprognostic (5.55e-2)" "unprognostic (6.01e-2)" "unprognostic (4.78e-2)" "unprognostic (2.35e-2)" "unprognostic (2.47e-1)" "prognostic unfavorable (4.42e-4)" "unprognostic (9.64e-3)" "unprognostic (1.17e-2)" "unprognostic (6.42e-3)" "unprognostic (4.21e-3)" 4.2 5.5 4.2 5.9 5.2 8.8 9.0 3.1 3.6 10.1 3.9 5.5 10.0 2.5 4.7 39.3 2.5 2.3 4.0 2.8 3.4 8.8 3.6 12.3 6.7 5.5 5.3 2.8 5.5 11.0 7.9 6.6 5.6 19.3 3.2 1.2 18.4 3.6 4.0 71.2 9.7 1.1 3.3 23.4 6.1 3.7 6.6 6.9 7.6 0.6 7.8 9.2 18.4 3.6 27.7 7.3 4.1 7.6 4.4 1.9 27.8 8.5 4.7 5.3 4.7 16.0 16.9 8.9 3.7 5.3 7.6 43.7 3.3 22.2 4.4 7.3 2.3 18.6 4.9 4.2 2.0 5.1 6.3 1.2 27.1 7.3 7.1 1.6 3.6 8.1 10.2 21.5 4.9 16.4 14.3 13.8 5.3 17.7 12.3 14.1 7.0 11.7 4.1 19.6 7.7 9.1 7.4 84.0 3.8 1.7 34.9 7.5 4.8 12.6 9.1 11.5 9.6 7.8 7.3 3.8 2.0 13.2 9.2 543.5 28.3 163.4 13.2 160.6 11.7 7.0 23.7 27.2 36.2 11.7 28.1 27.9 15.3 6.9 248.6 3.9 43.0 24.2 4.2 5.2 3.1 3.6 2.8 3.4 5.5 5.3 5.6 3.3 6.6 3.6 3.5 0.0 7.0 0.0 18.5 32.6 17.0 31.6 71.7 0.3 26.7 20.1 2.9 7.2 15.7 11.0 0.0 41.5 24.3 5.1 1.9 10.1 9.9 3.0 1.7 8.0 10.8 16.2 0.5 6.0 138.2 3.6 5.1 5.2 51.5 1.4 17.2 0.7 20.0 5.0 0.4 8.8 16.2 36.7 74.2 24.3 3.4 70.0 7.2 1.9 29.9 0.3 25.7 0.5 0.1 13.4 7.8 1.9 3.5 20.9 16.1 2.4 7.4 2.6 6.6 1.1 4.3 3.4 4.9 57.7 36.8 31.3 26.1 14.2 10.4 24.6 FAM117B "ALS2CR13, FLJ38771" ENSG00000138439 "Family with sequence similarity 117 member B" Q6P1L5 2 202634969-202769757 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 45.8;Inhibitory neurons: 49.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003229, HPA028746" Uncertain Approved Nucleoplasm,Centrosome Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Centrosome "HPA003229: AB_2246696, HPA028746: AB_2672760" "unprognostic (1.39e-2)" "unprognostic (1.47e-1)" "unprognostic (1.53e-2)" "unprognostic (4.59e-2)" "unprognostic (1.07e-2)" "unprognostic (4.07e-3)" "unprognostic (1.55e-2)" "unprognostic (4.84e-2)" "unprognostic (6.21e-2)" "unprognostic (2.55e-2)" "unprognostic (8.40e-3)" "unprognostic (5.75e-1)" "unprognostic (6.01e-2)" "unprognostic (8.93e-2)" "unprognostic (3.18e-1)" "unprognostic (8.59e-2)" "unprognostic (1.37e-3)" 3.1 7.5 5.1 4.5 5.4 2.9 3.3 7.0 7.1 2.7 0.7 4.9 4.3 2.9 2.9 5.4 3.8 3.0 1.8 5.0 6.3 4.9 1.9 2.9 7.2 3.1 3.8 5.1 4.6 7.3 3.5 6.9 3.6 5.1 4.7 2.6 3.3 3.0 1.5 5.0 3.7 2.0 3.3 5.4 4.1 5.8 6.4 9.6 2.8 1.8 7.4 3.8 3.2 4.1 2.0 2.4 10.5 7.2 3.5 1.9 10.2 0.6 0.9 0.6 1.1 3.1 4.2 8.2 6.5 1.2 1.6 1.9 9.0 4.6 1.7 0.2 7.2 6.9 4.3 11.6 2.8 5.9 3.0 2.6 6.3 1.3 1.9 4.7 2.8 10.8 10.1 1.6 0.6 3.9 16.1 12.1 10.7 5.8 4.5 12.5 2.1 9.8 5.5 5.2 17.7 15.4 8.0 5.3 3.9 8.7 2.2 8.1 1.7 1.2 2.4 1.9 1.1 5.9 3.6 10.8 2.4 4.5 1.3 0.4 3.9 1.5 1.3 8.2 3.4 8.1 3.0 2.7 4.5 7.7 8.2 5.7 2.2 4.4 9.1 1.5 1.2 3.1 5.1 5.4 7.0 7.1 5.0 6.3 3.1 3.8 3.6 3.3 6.4 4.1 9.7 3.2 7.5 13.1 21.5 17.2 2.9 3.0 12.0 4.9 8.1 4.3 4.9 12.8 2.6 18.4 4.2 8.4 8.8 11.7 0.0 10.2 2.2 8.6 6.5 4.9 25.8 3.0 45.8 6.4 6.3 6.1 7.1 10.1 5.7 15.3 8.2 2.2 2.8 6.7 49.7 11.8 2.0 27.4 13.9 1.4 13.1 17.1 3.6 23.4 17.1 1.7 3.1 29.1 29.4 5.8 9.7 23.7 5.2 6.7 4.9 5.9 3.0 2.7 6.6 2.0 4.1 5.0 16.3 29.2 19.9 2.7 10.1 11.1 13.8 6.0 FAM131A "C3orf40, MGC21688" ENSG00000175182 "Family with sequence similarity 131 member A" Q6UXB0 3 184335926-184348421 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 55.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042800 Uncertain Approved "Nucleoli rim,Mitotic chromosome" Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 40: Granulosa cells - Unknown function" "Nucleoli rim" "Mitotic chromosome" "HPA042800: AB_10797023" "unprognostic (1.02e-2)" "unprognostic (1.44e-1)" "unprognostic (2.41e-3)" "prognostic unfavorable (2.22e-4)" "unprognostic (2.88e-1)" "unprognostic (4.84e-2)" "unprognostic (2.92e-3)" "unprognostic (1.57e-1)" "unprognostic (7.54e-2)" "unprognostic (7.02e-2)" "unprognostic (6.54e-2)" "unprognostic (1.19e-1)" "unprognostic (1.72e-1)" "unprognostic (3.41e-2)" "unprognostic (1.56e-1)" "unprognostic (2.87e-1)" "unprognostic (1.28e-2)" 15.6 22.7 42.8 5.4 51.1 3.2 13.5 25.0 57.6 17.3 20.5 26.4 7.5 19.1 5.0 13.2 20.6 10.2 29.6 68.2 39.2 13.3 5.5 16.9 4.4 29.5 27.5 24.1 13.7 14.5 54.8 5.8 29.9 17.0 3.7 4.8 10.8 12.3 17.3 30.1 13.8 10.0 22.5 10.7 16.6 16.4 38.8 3.1 12.8 18.0 2.9 17.1 15.2 40.1 14.5 6.1 9.5 16.3 12.1 10.2 8.8 6.5 13.7 9.6 7.5 4.7 5.1 2.1 25.9 6.0 20.7 13.5 0.0 11.8 5.8 15.7 16.0 0.1 9.4 10.2 12.4 0.3 10.8 7.3 1.9 8.4 19.2 9.2 19.4 9.7 3.2 2.1 3.3 11.3 5.6 0.3 16.1 8.7 11.8 10.4 4.0 14.0 9.8 0.5 28.2 29.3 4.1 10.5 14.7 5.9 31.9 3.3 20.2 12.1 9.3 9.9 20.0 22.9 15.4 1.5 38.5 2.1 8.3 1.5 3.8 4.8 1.1 4.9 1.2 1.4 0.8 1.1 4.2 1.4 0.9 1.1 8.3 1.2 2.7 1.7 1.7 2.2 42.8 51.1 25.0 57.6 68.2 39.2 29.5 27.5 29.9 22.5 38.8 40.1 15.5 6.4 5.0 13.7 5.5 11.1 20.0 6.1 5.7 24.0 8.0 11.0 7.6 14.3 4.1 14.7 14.6 9.0 4.6 11.6 1.9 6.0 4.4 6.5 10.5 11.5 9.6 6.1 30.8 3.5 3.5 9.7 5.1 11.0 7.0 55.9 13.6 1.4 7.9 23.5 16.6 7.5 6.1 5.7 14.2 2.5 18.6 7.7 1.8 11.2 9.6 13.1 6.2 6.6 11.9 10.7 9.6 20.7 2.5 15.2 15.7 3.4 15.8 15.9 6.6 13.0 14.4 12.9 7.1 3.5 14.6 33.2 5.0 20.0 8.7 15.9 FAM222A "C12orf34, FLJ14721" ENSG00000139438 "Family with sequence similarity 222 member A" Q5U5X8 12 109713825-109770495 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 33.3;Early spermatids: 29.1;Horizontal cells: 77.4;Oligodendrocytes: 78.5;Rod photoreceptor cells: 50.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "SH-SY5Y: 116.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040181, HPA075616" Uncertain Approved "Golgi apparatus,Cell Junctions,Midbody ring" Yes NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus" "Cell Junctions, Midbody ring" "HPA040181: AB_10796448, HPA075616: " "unprognostic (8.59e-3)" "prognostic favorable (1.82e-5)" "unprognostic (1.43e-1)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "unprognostic (2.05e-2)" "unprognostic (1.46e-2)" "unprognostic (1.03e-1)" "unprognostic (6.66e-2)" "unprognostic (8.17e-2)" "prognostic favorable (4.81e-4)" "unprognostic (1.15e-1)" "unprognostic (4.16e-2)" "prognostic favorable (8.59e-4)" "unprognostic (3.93e-2)" "unprognostic (2.77e-1)" "unprognostic (1.24e-1)" 0.7 19.0 23.7 0.7 45.2 0.6 1.2 36.7 34.2 0.6 5.6 1.9 4.8 0.3 0.8 2.3 0.4 0.8 8.9 20.0 27.6 10.6 4.0 2.1 0.4 41.2 43.1 13.4 3.9 0.7 22.4 0.1 37.7 1.8 1.0 22.1 3.4 0.5 4.3 3.2 2.2 0.4 29.0 6.2 7.2 23.4 48.4 0.4 0.7 0.6 0.6 0.9 1.8 65.6 2.0 3.1 1.6 3.7 1.0 0.0 1.1 0.6 0.3 1.6 0.2 28.1 0.5 0.3 2.2 0.8 1.7 1.2 1.9 0.1 0.6 16.8 4.0 3.5 0.9 6.5 0.2 2.8 3.6 0.2 0.2 0.3 0.0 0.4 0.1 2.0 1.2 0.6 0.3 11.5 0.7 3.6 3.0 3.3 5.3 2.3 8.0 1.2 3.5 1.5 19.2 116.4 2.5 3.7 8.2 0.5 4.5 3.0 0.2 0.5 3.2 1.3 2.4 2.9 4.0 2.4 0.3 2.1 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.7 45.2 36.7 34.2 20.0 27.6 41.2 43.1 37.7 29.0 48.4 65.6 2.1 0.0 0.0 2.3 3.6 2.2 0.9 0.1 3.4 23.4 7.4 6.1 8.1 1.5 0.8 1.8 33.3 0.3 10.4 1.2 7.9 1.7 29.1 1.2 0.5 1.3 7.7 0.0 1.3 0.8 0.2 1.5 1.5 1.8 0.0 0.7 0.7 1.3 0.3 77.4 6.7 5.8 0.0 0.0 2.1 13.4 1.2 1.9 7.2 0.0 0.1 11.2 0.0 9.5 78.5 1.1 0.2 0.4 1.3 1.7 0.9 0.7 0.6 50.3 0.0 2.6 1.5 1.1 5.7 3.3 1.8 0.8 3.7 6.0 1.6 0.4 FAM3A "2-19, DXS560S, XAP-7" ENSG00000071889 "FAM3 metabolism regulating signaling molecule A" P98173 X 154506159-154516242 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 116.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "EFO-21: 109.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025016, HPA035268, HPA056991" Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome" "Secreted to blood" Yes No 15000 "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "CAB025016: , HPA035268: , HPA056991: AB_2683303" "unprognostic (1.60e-1)" "unprognostic (2.72e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (3.19e-2)" "unprognostic (4.73e-2)" "unprognostic (5.19e-2)" "unprognostic (2.54e-2)" "unprognostic (2.57e-2)" "unprognostic (2.53e-1)" "unprognostic (6.27e-2)" "unprognostic (3.42e-2)" "unprognostic (3.48e-2)" "unprognostic (1.31e-2)" "unprognostic (2.74e-1)" "unprognostic (1.41e-1)" "unprognostic (4.04e-1)" "unprognostic (9.71e-2)" 28.4 37.3 43.5 11.3 49.1 11.3 27.6 50.8 51.3 44.6 38.8 35.3 28.0 36.0 7.7 41.3 38.9 8.4 58.7 40.6 45.8 38.6 63.1 26.8 9.4 52.2 47.6 51.5 52.0 14.8 40.9 10.1 47.8 39.1 6.8 6.1 28.5 12.7 36.8 31.1 33.8 7.4 46.9 28.2 36.1 10.0 46.4 12.1 39.9 13.7 5.5 35.8 35.3 58.1 44.4 41.1 10.3 34.5 30.3 15.4 28.8 22.3 15.1 14.8 17.6 19.1 26.2 28.5 109.2 36.8 29.0 31.6 16.2 19.3 3.6 23.4 21.7 11.2 36.9 13.8 47.2 7.6 17.6 19.0 17.5 30.7 21.4 17.7 10.5 18.1 21.6 20.5 17.3 46.3 14.2 32.7 4.6 47.8 52.4 17.3 10.4 79.6 16.6 18.0 20.4 15.6 10.3 24.4 37.3 7.4 18.7 11.8 12.0 19.9 12.0 54.7 30.6 77.6 46.5 36.0 36.4 19.6 20.8 23.4 10.8 15.2 13.4 12.7 13.2 6.1 8.6 9.6 11.0 8.7 10.0 12.0 5.8 10.6 11.3 14.6 9.1 10.1 43.5 49.1 50.8 51.3 40.6 45.8 52.2 47.6 47.8 46.9 46.4 58.1 23.5 12.8 16.7 13.1 16.9 16.3 23.4 29.2 22.8 25.4 21.9 24.9 21.9 22.8 16.3 22.0 14.6 47.0 19.3 60.2 27.4 27.6 1.0 13.4 18.3 18.3 17.5 29.9 7.1 42.5 50.0 28.4 50.0 15.0 5.7 34.8 23.6 30.3 29.8 21.9 9.4 58.9 18.3 16.4 15.3 2.8 33.5 18.0 33.8 6.5 17.6 28.9 24.7 11.1 14.3 28.2 57.5 29.3 32.5 28.7 116.2 33.1 12.7 20.4 6.6 26.7 24.5 5.2 10.1 32.1 21.2 71.3 19.3 23.7 39.7 22.9 FAM50B "D6S2654E, X5L" ENSG00000145945 "Family with sequence similarity 50 member B" Q9Y247 6 3849373-3851320 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatogonia: 43.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 88.3;MCF7: 27.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA064111, HPA067817" Approved Enhanced "Nucleoplasm,Cytokinetic bridge,Midbody" Yes NA "Cluster 15: NK-cells - Transcription" "Cluster 47: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "Cytokinetic bridge, Midbody" "HPA064111: AB_2685191, HPA067817: AB_2685904" "unprognostic (1.15e-1)" "unprognostic (7.76e-2)" "unprognostic (4.28e-2)" "unprognostic (4.43e-2)" "unprognostic (2.12e-3)" "unprognostic (2.69e-1)" "unprognostic (2.38e-2)" "unprognostic (7.13e-2)" "unprognostic (1.60e-1)" "unprognostic (1.79e-1)" "unprognostic (2.15e-1)" "unprognostic (2.90e-1)" "prognostic favorable (4.01e-6)" "unprognostic (1.60e-1)" "unprognostic (3.22e-1)" "unprognostic (1.34e-1)" "unprognostic (9.39e-2)" 6.9 9.1 11.7 3.7 14.3 1.8 7.0 12.3 15.1 8.3 8.5 10.2 6.6 9.7 3.9 6.6 8.8 3.7 18.0 12.5 13.6 9.8 12.9 5.3 5.1 11.7 11.1 9.3 9.2 4.2 10.4 1.7 11.5 6.4 1.4 5.5 10.2 5.8 32.1 7.1 6.5 2.8 11.2 7.1 8.1 14.0 13.0 3.9 9.8 8.8 3.5 9.7 6.3 12.6 6.6 8.7 0.1 0.0 4.9 4.7 0.4 7.6 3.7 5.1 6.5 0.0 11.7 7.0 8.0 5.5 2.0 4.9 0.0 3.0 3.8 88.3 4.6 0.0 21.1 0.0 5.2 0.0 0.1 5.2 6.0 4.0 1.1 1.6 5.1 0.0 0.0 0.0 4.6 27.5 0.0 9.8 1.9 4.0 4.1 0.0 0.0 0.0 2.5 0.0 11.8 10.3 12.4 7.7 0.4 0.0 8.4 7.8 7.2 0.0 0.9 10.1 0.0 0.0 19.7 0.0 2.7 0.6 14.1 5.7 7.9 4.4 11.3 10.8 26.7 25.0 21.8 14.6 10.5 20.8 17.7 11.2 3.3 33.8 17.7 17.3 36.0 9.0 11.7 14.3 12.3 15.1 12.5 13.6 11.7 11.1 11.5 11.2 13.0 12.6 11.4 16.0 7.0 2.6 8.3 6.4 5.7 10.2 15.4 18.1 8.7 13.5 19.8 17.2 8.3 12.9 4.2 4.2 9.3 2.3 33.2 13.5 31.5 6.8 5.0 6.7 1.2 6.7 2.5 11.1 6.9 8.0 7.1 3.3 3.8 7.5 11.0 21.6 10.1 15.2 2.6 3.5 8.2 6.8 4.7 28.8 8.4 5.6 12.4 1.0 8.7 20.9 4.1 1.0 4.6 8.5 5.1 10.9 6.9 3.3 7.4 36.9 6.8 16.0 0.0 13.0 8.4 38.3 43.9 12.5 6.7 1.0 6.1 7.8 3.8 2.1 FAM83D "C20orf129, CHICA, dJ616B8.3" ENSG00000101447 "Family with sequence similarity 83 member D" Q9H4H8 20 38926312-38953106 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 84.7;intestine: 83.1;smooth muscle: 95.3" "Group enriched" "Detected in many" 4 "Basal squamous epithelial cells: 44.9;Erythroid cells: 72.6;Extravillous trophoblasts: 67.5;Squamous epithelial cells: 71.7;Syncytiotrophoblasts: 152.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "B-cells: 1.1;NK-cells: 1.1;T-cells: 2.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA049333, HPA060854" Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes Yes "Cluster 26: Non-specific - Mitochondria" "Cluster 37: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 61: Squamous epithelial cells - Keratinization" "Mitotic spindle" "Microtubules, Cytokinetic bridge, Cytosol" "HPA049333: AB_2680717, HPA060854: " "unprognostic (7.90e-3)" "unprognostic (4.34e-2)" "unprognostic (6.41e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (1.95e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (5.44e-6)" "prognostic unfavorable (9.69e-4)" "unprognostic (2.21e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (4.73e-5)" "unprognostic (3.52e-2)" "prognostic unfavorable (1.81e-14)" "unprognostic (2.57e-3)" "unprognostic (5.74e-2)" "unprognostic (2.82e-1)" "unprognostic (4.87e-2)" 1.6 1.8 0.8 7.2 1.6 23.3 1.1 0.9 1.4 4.1 0.2 83.1 8.4 1.0 1.6 84.7 1.0 13.6 1.0 0.9 0.5 5.7 3.7 5.2 4.5 0.5 0.4 0.5 0.4 0.2 0.4 3.4 0.5 16.2 8.6 0.2 7.8 1.7 0.2 10.2 34.7 95.3 0.5 1.9 44.9 5.0 0.5 6.6 1.0 0.2 12.2 27.0 17.1 0.9 112.2 67.3 52.0 44.0 5.8 6.5 93.6 49.3 30.2 94.7 57.4 103.4 49.7 28.3 47.6 32.1 73.4 93.1 71.8 83.9 87.9 9.4 28.6 32.6 50.7 75.2 4.7 14.6 16.5 3.3 4.2 54.6 31.4 11.4 52.7 12.3 29.6 39.5 54.4 59.7 22.7 21.3 43.2 64.4 85.1 21.8 96.0 15.6 27.6 28.0 24.3 40.2 143.0 117.4 20.6 48.1 73.6 14.9 25.4 62.4 76.4 71.6 110.1 12.0 19.6 29.0 28.1 21.2 46.7 0.0 0.0 0.0 0.2 0.1 0.9 0.6 1.0 1.1 0.0 1.1 1.1 1.4 0.0 1.1 0.1 0.0 2.0 0.5 0.8 1.6 0.9 1.4 0.9 0.5 0.5 0.4 0.5 0.5 0.5 0.9 3.9 0.0 1.3 0.3 2.3 2.3 5.8 7.0 44.9 0.0 2.8 9.0 0.8 1.5 18.0 0.0 0.0 17.3 6.3 6.5 0.0 0.1 0.5 1.1 1.6 2.2 1.8 72.6 3.7 0.0 67.5 2.7 18.3 2.1 0.0 8.2 1.8 5.7 4.8 0.0 1.2 6.0 4.1 1.6 0.5 0.6 0.3 2.6 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.1 6.0 0.0 12.5 1.6 1.7 8.3 4.5 0.0 19.7 0.3 4.0 15.7 18.3 71.7 1.8 152.6 5.2 0.3 10.2 4.1 FAN1 "KIAA1018, MTMR15" ENSG00000198690 "FANCD2 and FANCI associated nuclease 1" Q9Y2M0 15 30890559-30943108 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Endonuclease, Exonuclease, Hydrolase, Nuclease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048198 Supported "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 14: Monocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA048198: AB_2680311" "unprognostic (7.18e-3)" "unprognostic (5.63e-2)" "unprognostic (1.96e-1)" "unprognostic (3.30e-2)" "unprognostic (6.99e-2)" "unprognostic (2.86e-1)" "unprognostic (1.97e-1)" "unprognostic (1.19e-1)" "unprognostic (5.94e-2)" "unprognostic (3.53e-2)" "unprognostic (3.53e-2)" "unprognostic (9.67e-2)" "prognostic favorable (1.42e-6)" "unprognostic (3.73e-1)" "unprognostic (1.19e-1)" "unprognostic (8.93e-3)" "unprognostic (1.29e-1)" 6.2 8.5 9.3 0.9 9.5 0.5 6.7 9.4 9.7 10.1 9.3 10.7 0.9 9.2 6.6 6.5 9.0 1.2 8.8 8.9 9.5 9.5 9.6 5.5 0.8 9.7 9.8 11.8 12.7 5.9 11.4 3.0 10.0 11.5 2.0 2.7 9.8 1.4 18.7 10.8 7.3 2.4 9.5 6.8 8.6 8.9 9.9 4.4 10.0 7.3 0.7 9.3 9.7 10.0 5.2 9.9 3.6 1.9 12.4 9.3 0.8 4.4 2.1 4.7 5.0 4.5 1.7 0.6 7.6 3.6 7.4 9.2 4.7 9.4 5.0 4.2 1.4 1.3 5.5 1.9 4.8 1.2 1.9 2.8 7.3 3.0 7.3 7.2 3.4 5.7 4.7 6.1 4.7 0.6 8.6 3.1 2.2 11.5 2.8 7.0 12.0 2.3 6.7 2.3 4.5 4.6 9.2 5.6 3.0 8.8 4.4 3.3 3.3 9.4 3.0 5.0 3.4 7.4 8.7 1.1 4.1 1.9 1.1 0.0 0.1 0.0 1.4 0.3 2.0 1.2 1.2 0.7 0.9 1.5 1.8 1.1 0.0 1.8 4.3 1.1 1.4 0.7 9.3 9.5 9.4 9.7 8.9 9.5 9.7 9.8 10.0 9.5 9.9 10.0 9.1 16.0 8.4 21.2 5.4 4.1 5.8 4.9 9.6 17.0 11.2 9.8 17.0 0.0 10.7 9.2 20.9 6.5 3.5 7.6 9.8 4.5 11.9 10.2 12.9 8.8 7.8 6.9 23.7 2.9 2.2 8.4 8.6 9.0 8.8 15.5 6.8 13.4 3.7 26.9 25.5 11.0 8.2 5.4 2.5 7.1 10.5 3.9 5.4 15.0 3.4 14.9 7.2 13.6 44.2 3.6 6.4 6.8 7.0 6.0 4.2 8.0 13.6 23.5 6.6 9.4 7.6 20.9 16.4 7.2 2.4 4.1 5.3 9.2 10.3 3.7 FBXL6 FBL6 ENSG00000182325 "F-box and leucine rich repeat protein 6" Q8N531 8 144355431-144359376 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 43.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008867 Approved Nucleoplasm,Vesicles Yes No "Cluster 14: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" Nucleoplasm Vesicles "HPA008867: AB_2668161" "unprognostic (2.97e-2)" "unprognostic (3.30e-2)" "unprognostic (1.13e-3)" "unprognostic (3.13e-1)" "unprognostic (9.88e-2)" "unprognostic (1.68e-1)" "unprognostic (6.29e-3)" "unprognostic (2.62e-1)" "unprognostic (1.10e-1)" "unprognostic (1.43e-2)" "unprognostic (9.04e-2)" "unprognostic (9.73e-2)" "prognostic unfavorable (4.49e-10)" "unprognostic (3.93e-2)" "unprognostic (1.44e-1)" "unprognostic (3.53e-1)" "unprognostic (2.00e-1)" 4.6 4.8 2.3 1.4 2.3 2.0 4.9 2.5 3.2 4.3 2.5 8.0 4.6 3.5 0.6 7.2 3.1 1.0 4.1 2.3 2.2 4.6 10.8 3.9 1.8 2.5 2.4 2.1 8.1 1.6 3.8 1.8 2.4 4.2 1.8 0.5 5.1 1.6 4.2 6.6 7.8 0.7 2.4 6.8 5.5 5.2 2.6 1.5 3.3 0.3 1.2 4.6 4.3 2.3 9.0 3.0 2.1 13.3 2.7 0.7 3.8 4.4 5.1 4.5 3.1 3.2 3.9 4.1 5.3 2.2 2.2 5.8 2.4 6.1 1.0 7.6 3.0 8.2 1.6 7.9 4.0 2.1 8.4 1.2 5.5 2.5 6.6 1.2 3.7 6.7 3.8 6.6 1.7 16.7 6.0 1.9 2.6 9.8 8.3 6.7 2.4 14.0 6.0 3.0 3.1 3.0 5.1 8.0 7.7 1.2 13.2 3.7 3.3 2.2 8.1 10.8 5.4 2.5 2.1 3.0 3.4 5.1 2.9 0.0 0.1 0.6 0.4 0.4 0.3 0.2 0.2 0.2 0.1 0.1 0.0 0.1 0.0 0.3 1.6 0.7 0.0 0.0 2.3 2.3 2.5 3.2 2.3 2.2 2.5 2.4 2.4 2.4 2.6 2.3 17.9 6.4 2.0 4.6 10.1 5.7 6.0 2.1 7.4 9.9 13.2 12.8 1.1 7.2 4.6 0.0 14.6 8.3 17.3 18.2 5.9 5.2 1.9 5.2 6.8 5.9 2.4 3.0 7.4 6.2 11.6 5.2 13.7 7.8 1.3 7.7 6.8 6.7 6.9 1.7 5.6 19.4 2.0 4.7 7.6 1.6 5.3 9.0 5.4 4.7 2.6 7.9 6.2 2.0 2.7 7.5 10.8 1.9 20.1 8.2 43.7 8.1 2.0 9.0 0.0 5.1 13.6 5.0 7.8 14.8 6.7 3.8 10.7 9.9 17.3 6.3 FBXO38 "Fbx38, FLJ13962, MOKA, SP329" ENSG00000145868 "F-box protein 38" Q6PIJ6 5 148383935-148442836 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034821, HPA041444" Approved Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" Yes No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Plasma membrane" "Cytokinetic bridge, Cytosol" "HPA034821: AB_10669897, HPA041444: AB_2677484" "unprognostic (7.72e-2)" "unprognostic (5.75e-3)" "unprognostic (1.95e-2)" "unprognostic (1.67e-1)" "unprognostic (2.21e-1)" "unprognostic (2.70e-2)" "unprognostic (7.06e-2)" "unprognostic (5.43e-3)" "unprognostic (1.45e-1)" "unprognostic (1.12e-1)" "unprognostic (2.03e-1)" "unprognostic (6.29e-2)" "unprognostic (2.21e-3)" "unprognostic (1.31e-3)" "unprognostic (1.83e-1)" "unprognostic (1.64e-1)" "unprognostic (4.70e-3)" 12.8 11.5 7.3 12.9 8.4 9.8 13.9 8.1 9.9 14.1 8.2 12.5 9.6 12.5 11.1 10.5 10.0 11.5 17.4 7.0 7.7 12.9 18.0 14.5 14.6 8.0 7.6 12.3 9.5 18.5 10.2 13.8 8.0 14.6 13.0 11.0 11.5 12.0 18.7 12.2 11.6 12.3 7.5 14.4 12.5 12.4 7.8 20.2 12.2 16.8 15.6 13.8 11.2 9.9 12.6 13.2 20.1 14.7 22.1 24.6 10.4 16.1 30.7 22.4 30.5 19.6 15.1 18.2 15.5 26.2 23.6 17.2 21.2 20.3 26.8 20.1 13.6 10.8 19.0 13.3 21.9 29.6 17.0 24.0 17.1 21.6 21.1 24.0 30.7 16.6 12.2 19.1 22.3 5.1 18.8 13.8 9.4 13.9 19.8 16.6 29.3 18.4 21.7 14.5 17.9 17.3 21.4 14.2 21.2 17.1 15.0 21.2 20.2 20.4 7.3 10.8 18.2 23.3 25.1 15.3 20.3 16.6 15.8 15.1 6.1 9.1 5.0 8.0 5.5 4.9 4.7 5.0 7.5 3.8 4.8 6.2 11.2 7.7 15.2 3.7 7.4 4.9 7.3 8.4 8.1 9.9 7.0 7.7 8.0 7.6 8.0 7.5 7.8 9.9 10.6 16.0 45.7 25.1 13.8 3.3 5.5 7.4 7.4 10.3 8.5 6.7 18.7 11.5 10.6 11.0 10.4 7.5 13.4 11.3 5.9 8.8 11.2 8.9 9.9 10.8 9.6 7.2 40.2 6.7 6.8 11.8 14.8 10.4 15.8 9.6 11.4 16.9 12.6 13.5 37.4 10.1 6.1 24.9 6.4 2.9 9.0 17.8 3.6 38.4 12.3 5.9 12.3 33.2 44.4 9.9 8.9 18.4 11.0 8.6 9.3 9.3 16.4 9.0 0.0 6.9 7.8 20.6 8.6 9.2 3.8 12.3 12.1 11.2 9.0 8.7 FCGBP FC(GAMMA)BP ENSG00000275395 "Fc fragment of IgG binding protein" 19 39863323-39934626 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 206.9;salivary gland: 85.4;stomach 1: 85.5;thyroid gland: 99.9" "Cell type enriched" "Detected in many" 9 "Intestinal goblet cells: 6081.9" "Cancer enhanced" "Detected in all" "colorectal cancer: 63.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.6;Daudi: 1.8;JURKAT: 1.7;MOLT-4: 1.8;RH-30: 7.1" "HPA003517, HPA003564" Enhanced Approved "Golgi apparatus,Plasma membrane,Cytokinetic bridge" "Secreted in other tissues" Yes NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "Golgi apparatus, Cytokinetic bridge" "HPA003517: AB_1078838, HPA003564: AB_2231648" "unprognostic (1.65e-2)" "unprognostic (1.92e-2)" "unprognostic (1.62e-3)" "unprognostic (1.77e-2)" "unprognostic (2.04e-2)" "prognostic favorable (1.28e-5)" "prognostic unfavorable (4.74e-5)" "unprognostic (1.36e-2)" "unprognostic (1.83e-1)" "prognostic unfavorable (9.70e-6)" "unprognostic (9.44e-2)" "unprognostic (3.03e-2)" "unprognostic (5.92e-3)" "unprognostic (8.60e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (4.27e-4)" "unprognostic (2.08e-1)" 5.9 10.0 5.1 14.0 7.2 0.4 3.2 4.0 8.4 56.4 15.0 206.9 68.7 1.2 0.6 4.6 9.8 49.2 2.9 5.6 6.8 11.3 1.0 1.9 0.9 20.1 10.6 3.7 4.9 0.5 3.4 2.9 11.1 3.8 67.7 0.6 85.4 1.4 0.4 14.8 148.7 2.6 5.9 1.5 85.5 2.9 14.0 1.5 99.9 0.0 0.7 3.4 1.6 12.0 0.0 4.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.2 0.0 0.1 1.8 0.6 0.1 1.5 0.3 0.1 7.1 1.6 0.1 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.2 0.4 0.1 0.1 0.5 0.0 0.3 0.1 0.0 0.0 0.1 5.1 7.2 4.0 8.4 5.6 6.8 20.1 10.6 11.1 5.9 14.0 12.0 0.6 3.2 5.1 2.6 4.6 3.7 1.9 15.8 1.2 1.1 1.3 3.4 2.8 70.1 60.0 25.8 0.0 0.7 1.8 622.2 0.0 5.2 7.2 4.2 0.3 26.7 81.1 0.0 0.6 0.9 0.4 1.9 552.0 4.0 15.9 0.4 0.7 1.3 44.0 0.0 0.4 6081.9 2.0 30.2 12.6 9.2 0.9 21.6 8.8 15.9 0.9 0.4 1.0 0.5 0.2 3.9 253.6 0.0 2.1 13.8 413.5 1.2 11.0 2.0 59.2 0.5 1.1 0.5 2.4 0.4 6.8 0.4 5.6 0.9 191.4 164.1 FCHSD2 "KIAA0769, SH3MD3" ENSG00000137478 "FCH and double SH3 domains 2" O94868 11 72836745-73142318 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 219.6;Microglial cells: 387.8;Oligodendrocyte precursor cells: 471.0;Oligodendrocytes: 198.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 164.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038545, HPA038546" Uncertain Approved "Nuclear speckles,Plasma membrane,Actin filaments,Focal adhesion sites" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Actin filaments" "Nuclear speckles, Focal adhesion sites" "HPA038545: AB_2676074, HPA038546: AB_10673013" "unprognostic (1.80e-2)" "unprognostic (1.50e-2)" "prognostic favorable (1.71e-4)" "unprognostic (1.63e-1)" "unprognostic (3.14e-2)" "unprognostic (2.62e-3)" "unprognostic (1.41e-2)" "unprognostic (2.62e-1)" "unprognostic (1.27e-2)" "unprognostic (2.56e-1)" "unprognostic (3.69e-2)" "unprognostic (6.16e-2)" "unprognostic (2.89e-3)" "unprognostic (2.02e-1)" "unprognostic (4.70e-1)" "unprognostic (2.92e-1)" "unprognostic (1.23e-1)" 22.2 19.2 43.3 33.4 47.9 28.6 16.8 31.5 38.7 14.9 34.6 14.5 8.9 16.0 6.9 11.7 13.8 22.6 25.5 37.0 44.5 13.0 17.6 23.9 45.2 36.6 36.4 32.3 10.4 9.9 8.1 31.2 35.4 11.6 14.4 19.6 9.3 13.8 8.8 9.0 17.7 17.2 32.5 42.3 13.1 22.6 41.3 28.5 14.9 14.7 46.1 21.6 11.7 45.0 14.2 12.3 26.0 31.3 9.8 23.9 21.8 26.7 50.6 14.8 12.0 9.6 21.0 76.3 31.3 31.0 15.6 20.0 15.3 14.1 21.0 27.2 7.0 64.2 14.3 33.4 25.7 30.6 7.6 14.6 15.6 15.1 17.7 33.4 35.7 26.7 13.7 49.6 19.5 16.1 36.4 54.7 5.5 15.6 13.8 56.4 39.8 164.1 24.8 21.4 13.1 16.9 9.6 16.2 31.9 12.2 12.4 23.7 47.9 45.9 18.5 32.9 7.5 46.8 29.4 71.2 8.4 51.4 13.8 18.3 8.4 18.7 2.8 5.1 1.9 22.2 2.8 3.2 8.1 26.9 3.2 4.1 19.9 2.0 3.0 32.3 3.2 3.6 43.3 47.9 31.5 38.7 37.0 44.5 36.6 36.4 35.4 32.5 41.3 45.0 47.3 9.6 14.0 114.9 76.7 8.5 5.2 3.6 9.1 13.5 5.9 4.7 16.0 8.6 6.1 3.7 25.0 12.4 39.4 1.9 1.9 4.1 6.2 6.6 8.3 30.2 4.8 19.4 79.4 6.2 9.2 9.4 7.7 5.4 2.5 33.6 46.1 11.3 19.9 10.1 219.6 7.7 4.1 30.8 29.9 10.0 10.8 32.8 5.4 387.8 20.6 10.6 5.2 471.0 198.1 5.3 5.7 16.6 70.1 3.8 1.8 3.5 3.9 17.0 6.6 13.0 26.1 9.6 13.0 7.1 5.8 12.0 14.9 6.0 3.7 4.8 FKBPL "DIR1, NG7, WISp39" ENSG00000204315 "FKBP prolyl isomerase like" Q9UIM3 6 32128707-32130288 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 51.2;Squamous epithelial cells: 34.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043478, HPA060158" Approved Approved "Nucleoplasm,Mitotic spindle" Yes No "Cluster 17: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Mitotic spindle" "HPA043478: AB_2678500, HPA060158: AB_2684213" "unprognostic (1.80e-1)" "unprognostic (6.80e-2)" "unprognostic (1.14e-1)" "unprognostic (1.03e-3)" "unprognostic (1.02e-1)" "unprognostic (7.67e-2)" "unprognostic (8.22e-3)" "unprognostic (2.25e-2)" "unprognostic (1.22e-1)" "prognostic favorable (8.46e-4)" "unprognostic (1.30e-1)" "unprognostic (8.96e-2)" "unprognostic (5.79e-2)" "unprognostic (7.32e-2)" "unprognostic (4.39e-2)" "unprognostic (2.70e-1)" "unprognostic (1.13e-1)" 3.3 4.2 2.9 2.0 2.5 2.8 4.0 2.2 3.2 3.8 2.2 4.1 1.6 3.1 6.1 10.7 4.3 1.6 2.9 2.6 2.4 4.0 5.2 3.2 3.1 2.9 2.4 3.2 5.5 4.0 2.9 1.7 2.6 3.2 3.4 1.8 6.4 1.1 4.5 9.8 3.6 3.6 2.1 4.7 6.1 6.2 2.5 5.5 5.6 4.4 1.1 2.9 5.1 3.6 0.0 0.9 8.1 13.8 11.6 8.2 3.4 5.4 6.1 10.0 9.7 17.5 7.3 0.0 1.8 9.3 13.1 4.2 11.3 10.5 6.9 0.0 13.7 0.0 11.9 10.2 6.5 0.0 6.6 8.0 5.6 19.3 6.1 7.3 10.6 15.8 11.9 15.0 10.2 6.0 6.9 5.9 6.0 16.1 3.0 0.0 5.0 13.6 10.4 1.5 15.3 1.0 5.5 9.6 10.2 2.4 16.8 11.8 4.7 14.3 4.1 7.5 13.3 7.7 1.5 5.7 5.6 7.1 9.1 6.6 1.8 0.5 0.7 2.5 0.7 2.1 1.1 1.3 1.9 0.5 1.0 1.0 2.6 3.4 0.8 1.6 0.3 1.5 2.9 2.5 2.2 3.2 2.6 2.4 2.9 2.4 2.6 2.1 2.5 3.6 8.8 6.4 5.9 0.3 7.8 11.2 4.7 6.7 51.2 2.9 11.5 8.5 2.0 7.2 6.2 1.8 0.0 9.9 6.1 9.3 5.9 8.1 4.2 11.6 6.1 9.6 6.0 19.8 0.7 6.7 13.3 5.6 6.1 8.1 2.5 12.4 5.0 3.3 5.0 10.1 0.6 7.0 8.2 2.8 8.8 5.5 2.8 4.2 7.2 1.0 3.7 7.3 3.1 0.0 0.5 6.0 6.2 3.4 7.7 5.2 10.3 9.9 3.2 4.9 0.0 5.4 17.4 11.1 8.8 34.1 10.2 14.1 6.8 14.9 6.5 4.1 FLI1 "EWSR2, SIC-1" ENSG00000151702 "Fli-1 proto-oncogene, ETS transcription factor" Q01543 11 128686535-128813267 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 35.8" "Cell type enhanced" "Detected in many" "B-cells: 65.7;Endothelial cells: 84.2;Hepatic stellate cells: 64.6;Kupffer cells: 86.4;Microglial cells: 231.4;monocytes: 68.4;NK-cells: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 113.9;HUVEC TERT2: 60.5;REH: 49.8;TIME: 63.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065030, HPA073099" Approved Supported "Nucleoplasm,Nuclear bodies" Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" "HPA065030: , HPA073099: AB_2686572" "unprognostic (1.38e-2)" "unprognostic (7.46e-2)" "unprognostic (6.16e-2)" "unprognostic (3.74e-2)" "unprognostic (6.22e-2)" "unprognostic (4.26e-3)" "unprognostic (1.33e-1)" "unprognostic (8.32e-3)" "unprognostic (2.97e-1)" "unprognostic (9.91e-2)" "unprognostic (1.60e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.79e-2)" "unprognostic (2.07e-2)" "unprognostic (2.62e-1)" "unprognostic (4.79e-2)" 10.2 1.9 3.7 10.9 2.3 12.2 6.0 2.1 2.8 5.7 1.2 3.7 3.2 4.6 1.1 2.8 2.7 6.1 6.2 1.8 2.9 2.1 2.8 10.8 12.3 4.7 2.7 1.2 1.7 3.5 0.7 12.5 4.3 1.9 2.9 0.5 2.2 2.2 2.8 1.7 4.0 5.9 3.5 35.8 4.3 0.9 3.9 17.2 2.9 6.6 10.4 6.7 1.9 2.8 0.2 0.0 5.6 0.0 0.8 1.0 0.1 3.3 9.2 3.8 3.1 0.0 0.0 18.5 31.7 11.1 1.1 0.1 0.8 13.5 4.1 9.0 0.2 113.9 0.5 0.0 6.0 13.7 14.6 0.8 1.1 7.7 17.3 11.1 60.5 25.6 0.0 23.3 0.8 0.0 13.3 8.1 1.8 0.0 3.1 49.8 0.1 19.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.0 0.0 20.4 63.0 0.7 0.0 0.2 3.5 7.3 16.4 16.6 0.1 31.8 5.2 34.5 15.5 24.5 10.1 15.3 11.9 6.8 8.9 8.2 19.1 6.0 3.7 8.2 11.8 12.3 19.1 3.3 11.1 20.1 3.7 2.3 2.1 2.8 1.8 2.9 4.7 2.7 4.3 3.5 3.9 2.8 53.4 6.4 5.3 0.3 65.7 5.1 0.3 1.7 2.2 0.0 0.7 1.3 5.5 5.7 0.1 1.8 0.0 0.4 43.1 0.0 0.0 0.0 0.5 0.4 0.6 84.2 0.0 23.4 0.3 0.0 0.4 5.9 2.0 0.3 22.8 0.0 64.6 1.3 43.2 0.0 1.5 0.1 0.0 86.4 24.7 0.5 1.8 60.3 7.2 231.4 68.4 0.1 93.7 4.0 0.7 0.0 0.0 0.7 56.9 0.3 0.0 0.4 0.8 0.4 6.6 2.1 3.1 0.2 0.1 0.6 4.1 0.3 52.8 0.9 0.2 0.4 FOS "AP-1, c-fos" ENSG00000170345 "Fos proto-oncogene, AP-1 transcription factor subunit" P01100 14 75278826-75282230 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 504.8" "Lineage enriched" "Detected in many" 6 "granulocytes: 504.8" "Cell line enhanced" "Detected in many" "hTCEpi: 453.1;OE19: 170.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "cerebellum: 80.9;spinal cord: 235.3" HPA018531 Approved Supported Nucleoplasm Yes No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA018531: AB_1846576" "unprognostic (1.18e-2)" "unprognostic (8.70e-2)" "unprognostic (1.61e-1)" "unprognostic (3.80e-1)" "unprognostic (3.08e-2)" "unprognostic (4.82e-2)" "unprognostic (2.09e-1)" "unprognostic (3.30e-1)" "unprognostic (9.55e-3)" "unprognostic (4.20e-3)" "unprognostic (1.04e-1)" "prognostic favorable (7.81e-4)" "unprognostic (3.20e-2)" "unprognostic (1.52e-2)" "unprognostic (3.22e-1)" "unprognostic (1.43e-1)" "unprognostic (2.66e-2)" 1136.1 735.7 62.9 576.0 87.2 2270.6 477.4 184.8 113.1 700.5 111.5 479.5 235.3 410.4 58.4 1250.8 1777.3 1160.0 513.1 58.9 190.7 266.1 308.8 486.9 449.9 145.1 84.0 1188.7 298.4 264.7 452.3 417.4 92.0 791.1 627.4 233.3 555.6 462.3 99.1 1645.4 584.5 964.3 100.6 178.0 525.6 87.2 104.4 424.2 1007.6 1014.2 26.8 946.5 346.6 121.7 2.2 1.4 7.1 10.4 59.9 18.3 42.1 6.4 2.4 4.5 3.2 4.4 12.6 0.6 1.8 43.5 42.6 3.0 3.6 74.7 1.1 1.2 1.1 1.0 21.9 1.9 27.6 2.6 42.8 44.3 453.1 3.9 27.4 6.2 2.7 9.2 2.0 19.7 1.2 26.1 0.9 12.9 7.4 170.9 2.5 2.0 1.4 23.8 18.8 20.4 52.4 3.6 9.8 85.9 39.8 21.8 1.4 9.2 6.3 0.4 5.7 3.7 2.0 52.4 61.2 9.6 2.9 8.0 5.7 38.3 81.0 89.5 0.3 20.1 0.4 0.3 0.2 0.7 69.6 0.2 0.2 0.1 504.8 4.6 2.5 1.5 0.4 27.7 62.9 87.2 184.8 113.1 58.9 190.7 145.1 84.0 92.0 100.6 104.4 121.7 3911.0 1102.6 1859.4 137.1 1015.9 859.7 1644.7 1577.5 4336.7 106.1 3184.1 2874.6 1027.6 1416.9 752.7 191.3 129.3 1506.7 1323.5 1648.6 17.6 690.9 17.4 1834.4 3720.3 1624.0 1628.0 290.5 4.9 528.1 2694.6 4146.8 2049.5 3656.5 1630.6 751.3 1317.2 207.2 1693.8 35.3 3.0 1967.2 793.5 2600.2 1540.4 53.5 943.8 2910.7 855.6 58.1 269.5 1119.5 10.3 6.0 1.8 383.5 1507.8 178.3 1256.1 1115.7 1675.1 20.0 354.4 406.9 1209.6 3390.9 2705.7 10.0 10.5 2438.0 1092.4 2283.3 1497.0 417.4 1366.2 298.4 FOXQ1 HFH1 ENSG00000164379 "Forkhead box Q1" Q9C009 6 1312098-1314758 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 107.2;urinary bladder: 53.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 60.4;Basal respiratory cells: 24.9;Collecting duct cells: 40.5;Gastric mucus-secreting cells: 67.2;Suprabasal keratinocytes: 45.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 39.0;HaCaT: 44.7;Hep G2: 93.8;OE19: 117.1;RT4: 38.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA059700 Supported Nucleoplasm Yes NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA059700: AB_2684107" "unprognostic (2.04e-3)" "unprognostic (3.44e-1)" "unprognostic (1.10e-1)" "unprognostic (7.18e-2)" "unprognostic (1.50e-3)" "unprognostic (2.15e-1)" "unprognostic (3.26e-2)" "unprognostic (1.15e-3)" "unprognostic (1.04e-2)" "unprognostic (1.06e-1)" "unprognostic (7.65e-3)" "prognostic favorable (6.68e-4)" "unprognostic (1.49e-2)" "unprognostic (3.16e-3)" "unprognostic (2.82e-1)" "unprognostic (3.93e-2)" "unprognostic (1.96e-2)" 0.3 0.0 6.9 0.2 5.2 0.0 1.4 7.1 7.1 6.7 3.8 0.8 10.4 0.9 0.3 11.3 3.9 5.4 0.0 4.7 5.1 9.8 6.4 4.0 0.0 5.6 6.0 0.0 6.5 0.1 2.5 1.1 6.0 8.9 0.4 0.1 30.4 1.1 0.2 25.7 0.6 0.0 5.3 0.0 107.2 0.2 7.5 0.6 3.6 0.6 8.0 53.5 16.9 4.7 16.0 1.4 0.0 0.0 0.0 0.0 0.0 0.7 13.5 0.1 0.1 39.0 22.6 0.0 0.7 0.0 0.1 44.7 0.0 1.7 0.0 0.0 1.1 0.0 8.2 93.8 0.0 0.0 2.4 0.0 16.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 117.1 0.8 0.0 0.0 0.0 0.4 38.2 0.3 0.0 3.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 15.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 5.2 7.1 7.1 4.7 5.1 5.6 6.0 6.0 5.3 7.5 4.7 0.3 16.0 10.6 0.0 0.0 60.4 3.2 24.9 6.8 0.0 5.3 5.1 0.8 0.0 16.8 40.5 0.0 0.0 0.0 0.0 1.9 3.0 0.0 5.2 3.0 0.4 0.0 0.0 1.2 13.4 0.0 1.4 67.2 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.1 0.0 2.9 0.0 0.0 0.7 1.8 15.9 0.0 0.0 0.0 0.0 0.5 11.8 0.0 0.0 0.2 0.6 0.0 6.2 5.0 0.0 0.0 0.0 1.6 0.0 0.0 22.2 45.5 0.0 0.3 0.0 0.0 3.9 FRYL "AF4p12, DKFZp686E205, KIAA0826, MOR2" ENSG00000075539 "FRY like transcription coactivator" O94915 4 48497357-48780322 "Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 81.5" "Cell type enriched" "Detected in all" 5 "Oligodendrocytes: 1148.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 13.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 13.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031106, HPA031107" Supported Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 38: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 1: K-562 - Erythropoiesis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Microtubules, Cytokinetic bridge" "HPA031106: AB_10600660, HPA031107: AB_10600536" "unprognostic (7.50e-2)" "unprognostic (9.72e-3)" "unprognostic (6.68e-3)" "unprognostic (3.22e-2)" "unprognostic (5.37e-2)" "unprognostic (2.03e-2)" "unprognostic (3.59e-2)" "unprognostic (4.80e-2)" "unprognostic (4.67e-2)" "unprognostic (2.08e-1)" "unprognostic (2.41e-2)" "unprognostic (4.68e-2)" "unprognostic (2.62e-2)" "unprognostic (3.32e-2)" "unprognostic (1.66e-1)" "unprognostic (1.01e-1)" "unprognostic (1.29e-2)" 8.8 5.4 12.2 13.2 43.5 15.0 7.9 26.6 22.6 8.4 0.8 37.9 10.4 8.4 3.7 6.6 6.1 8.3 8.6 12.1 19.9 8.4 5.7 9.7 13.4 34.8 23.4 7.9 5.6 20.3 2.7 10.5 31.2 6.5 36.7 29.2 6.8 6.6 4.5 10.2 12.8 9.2 22.2 10.8 10.7 6.3 25.7 16.7 7.9 12.0 13.1 10.2 3.4 81.5 19.7 11.6 26.8 16.4 11.3 16.1 14.5 18.1 17.4 17.6 21.2 9.4 14.7 25.0 14.3 19.3 32.9 11.8 17.8 28.1 37.9 14.3 6.1 45.6 11.3 4.3 7.0 31.6 16.8 11.6 10.5 24.0 24.9 16.4 26.4 21.3 14.8 9.2 22.9 9.6 34.5 10.9 4.6 8.9 9.8 25.4 35.0 4.7 15.7 20.8 23.1 9.9 17.7 5.2 9.9 12.8 6.8 19.6 40.3 19.8 25.5 10.1 35.3 12.4 17.5 22.1 16.6 20.6 19.8 13.5 0.9 1.8 2.0 1.4 1.6 1.5 1.8 1.7 1.0 1.2 2.0 1.9 2.8 2.7 1.0 1.7 1.3 0.7 12.2 43.5 26.6 22.6 12.1 19.9 34.8 23.4 31.2 22.2 25.7 81.5 87.1 38.5 33.1 92.1 50.1 47.3 24.3 32.0 38.7 45.3 23.7 17.0 33.5 18.6 28.9 16.5 135.5 23.6 59.9 122.8 3.9 13.8 11.6 48.2 29.0 74.8 79.5 80.6 110.1 11.6 21.5 23.7 128.4 56.8 46.9 25.6 48.9 15.2 19.4 47.1 172.5 195.1 38.7 30.1 34.0 3.9 17.1 40.1 26.6 214.5 35.1 32.8 63.8 146.8 1148.7 28.8 87.3 18.4 38.6 43.4 50.4 8.4 21.0 105.6 19.7 31.2 37.3 12.8 10.9 37.3 49.3 10.8 54.4 15.6 93.9 53.3 FTSJ3 SPB1 ENSG00000108592 "FtsJ RNA 2'-O-methyltransferase 3" Q8IY81 17 63819433-63830012 "Metabolic proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055544, HPA062628" Supported Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 39: Non-specific - mRNA processing" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA055544: AB_2682843, HPA062628: AB_2684813" "unprognostic (1.33e-1)" "unprognostic (1.41e-1)" "unprognostic (6.60e-2)" "unprognostic (7.82e-2)" "unprognostic (6.45e-2)" "unprognostic (2.92e-1)" "prognostic unfavorable (1.44e-5)" "unprognostic (1.27e-1)" "unprognostic (2.57e-1)" "unprognostic (2.41e-2)" "unprognostic (2.85e-1)" "unprognostic (1.12e-1)" "unprognostic (4.99e-2)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" "unprognostic (5.10e-1)" "unprognostic (3.43e-1)" 20.7 20.7 11.8 18.2 12.4 15.8 18.0 12.3 12.7 20.4 12.0 20.5 14.2 20.2 17.2 19.0 18.8 15.1 20.8 11.3 12.0 23.3 18.8 14.8 20.9 12.6 12.1 22.3 15.7 20.6 12.4 13.1 12.5 18.7 18.0 8.8 17.7 18.1 28.8 23.9 18.4 22.6 12.3 21.0 17.8 15.2 12.3 21.0 17.2 14.6 23.8 20.1 18.7 12.7 63.0 97.0 36.8 52.5 57.9 49.5 57.0 61.4 44.7 68.8 54.2 81.4 40.9 83.4 24.7 36.2 36.0 42.6 69.3 58.4 87.8 14.4 69.2 75.0 68.6 76.6 42.2 95.9 52.5 35.1 45.3 106.9 51.2 34.9 58.2 50.2 75.9 33.1 46.5 105.5 84.9 31.1 99.4 70.2 97.7 74.6 100.9 58.6 44.8 56.3 33.9 132.5 72.3 60.9 43.1 72.7 58.0 31.8 52.7 50.9 71.6 57.4 115.1 79.5 120.9 81.4 45.6 62.6 50.3 4.5 11.4 7.0 11.0 13.0 14.5 9.6 11.6 14.5 13.6 8.6 9.2 11.5 2.5 13.9 10.1 10.3 15.1 10.0 11.8 12.4 12.3 12.7 11.3 12.0 12.6 12.1 12.5 12.3 12.3 12.7 16.2 32.1 30.2 4.2 17.3 13.8 13.6 16.1 26.7 6.6 10.6 12.6 27.7 18.6 25.7 14.7 10.4 16.0 19.4 15.7 13.7 28.0 8.8 23.5 27.5 25.1 12.7 20.8 2.0 33.8 17.0 18.4 11.2 24.1 24.1 17.5 14.3 19.9 14.2 3.3 2.0 12.0 16.2 13.8 9.3 17.8 24.2 16.3 8.8 1.9 19.3 16.0 15.5 1.5 3.8 30.6 14.0 19.2 18.6 10.6 15.5 29.8 24.3 9.3 46.0 21.0 20.5 11.7 15.7 20.8 12.8 16.3 18.6 15.7 21.1 9.5 FUT9 Fuc-TIX ENSG00000172461 "Fucosyltransferase 9" Q9Y231 6 96015974-96215612 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 18.9;stomach 1: 23.2" "Cell type enhanced" "Detected in some" "Astrocytes: 776.4;Excitatory neurons: 333.5;Inhibitory neurons: 238.2;Oligodendrocyte precursor cells: 168.9;Oligodendrocytes: 224.7" "Cancer enhanced" "Detected in some" "glioma: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 2.9;OE19: 2.8;RT4: 6.5;SCLC-21H: 6.3;SK-BR-3: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070923 Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 22: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "Microtubules, Cytokinetic bridge, Cytosol" "HPA070923: AB_2686323" "unprognostic (1.60e-1)" "unprognostic (2.48e-1)" "unprognostic (5.99e-3)" "unprognostic (1.33e-1)" "unprognostic (2.40e-1)" "unprognostic (2.97e-1)" "unprognostic (1.35e-1)" "unprognostic (2.85e-1)" "unprognostic (1.45e-1)" "unprognostic (1.12e-1)" "unprognostic (6.43e-3)" "unprognostic (5.60e-2)" "unprognostic (1.65e-2)" "unprognostic (3.03e-2)" 0.0 0.4 10.5 0.0 12.6 0.0 0.6 14.5 11.7 0.0 0.0 0.1 2.1 0.2 0.0 0.0 0.2 0.0 0.0 11.8 13.6 0.2 0.0 0.0 0.0 3.4 18.9 0.0 4.8 0.0 0.4 0.4 3.2 0.2 0.0 0.5 0.0 0.2 0.1 0.1 0.0 0.0 5.5 0.0 23.2 0.0 15.3 0.0 0.1 0.0 0.0 0.9 0.0 6.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 1.4 2.8 0.0 0.0 0.0 0.0 0.0 6.5 6.3 0.1 0.0 3.6 0.0 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 12.6 14.5 11.7 11.8 13.6 3.4 18.9 3.2 5.5 15.3 6.4 0.0 0.0 0.0 776.4 0.2 0.0 0.6 0.0 0.0 4.2 1.4 1.7 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.5 0.1 1.3 0.0 0.0 333.5 2.0 0.0 0.1 56.1 1.4 0.0 0.4 0.0 0.0 0.1 0.0 238.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.1 0.0 0.2 0.0 168.9 224.7 0.5 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.2 GAS2 ENSG00000148935 "Growth arrest specific 2" O43903 11 22625509-22813055 "Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell shape, Growth arrest" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 39.7" "Group enriched" "Detected in some" 4 "Astrocytes: 39.8;Excitatory neurons: 114.9;Inhibitory neurons: 141.9;Oligodendrocytes: 83.9" "Cancer enhanced" "Detected in many" "liver cancer: 4.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Hep G2: 43.2;JURKAT: 24.0;Karpas-707: 85.2;SCLC-21H: 24.8;U-266/84: 30.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058904 Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" Yes NA "Cluster 30: Non-specific - Translation" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Nucleoplasm, Nucleoli" "HPA058904: AB_2683850" "unprognostic (5.48e-3)" "unprognostic (1.00e-1)" "unprognostic (6.85e-2)" "unprognostic (1.16e-2)" "unprognostic (7.87e-2)" "unprognostic (2.08e-2)" "unprognostic (1.08e-1)" "unprognostic (1.49e-1)" "unprognostic (1.23e-1)" "unprognostic (3.71e-2)" "unprognostic (1.70e-2)" "unprognostic (3.30e-5)" "prognostic favorable (6.13e-4)" "unprognostic (5.85e-2)" "unprognostic (4.22e-2)" "unprognostic (7.94e-2)" "unprognostic (3.58e-2)" 0.4 0.8 2.1 0.3 1.9 0.1 0.8 4.5 5.4 0.9 0.0 0.7 1.8 0.8 0.0 0.7 1.2 1.6 3.5 0.7 2.2 5.4 39.7 1.0 1.0 6.2 7.5 2.0 9.6 0.1 2.5 0.4 6.3 1.0 0.4 2.2 1.5 0.6 4.6 0.8 1.6 0.3 3.3 1.3 2.6 0.8 6.1 8.2 0.8 1.8 0.7 1.0 0.7 6.1 0.0 0.1 1.7 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.8 0.0 0.0 0.0 0.0 1.0 0.0 0.1 1.7 0.4 0.2 0.0 43.2 0.5 0.1 0.3 0.1 0.1 0.0 0.2 0.3 0.0 24.0 1.6 85.2 0.0 0.4 0.3 0.1 0.3 2.4 0.0 0.9 0.5 4.4 0.0 1.1 24.8 1.3 0.0 0.0 0.5 0.2 0.1 0.0 1.8 0.0 0.4 1.1 0.0 1.1 30.7 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 1.9 4.5 5.4 0.7 2.2 6.2 7.5 6.3 3.3 6.1 6.1 0.1 0.0 0.0 39.8 0.4 0.1 0.4 0.1 0.6 1.9 0.4 0.1 12.7 10.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.4 2.3 1.3 0.1 0.4 0.0 0.0 114.9 3.3 0.0 1.0 3.1 0.7 0.0 0.2 0.7 22.9 0.0 0.0 141.9 0.6 0.0 0.0 0.0 5.4 0.6 0.0 0.0 9.4 0.2 0.2 0.0 18.6 83.9 1.6 1.4 0.0 0.5 0.1 0.1 3.2 4.0 1.2 0.0 0.3 0.8 0.4 1.1 0.6 0.0 0.0 0.4 0.1 0.9 0.3 GATA6 ENSG00000141448 "GATA binding protein 6" Q92908 18 22169589-22202528 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Atrial septal defect, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 57.8;ovary: 73.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 97.6;Gastric mucus-secreting cells: 100.9;Granulosa cells: 52.9" "Cancer enhanced" "Detected in many" "stomach cancer: 26.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 23 "basophil: 4.0" "Lineage enriched" "Detected in single" 23 "granulocytes: 4.0" "Cell line enhanced" "Detected in many" "BEWO: 54.8;CACO-2: 69.7;hTERT-RPE1: 25.5;OE19: 37.6" "Not detected" "Not detected" "Not detected" "Not detected" "CAB011581, HPA066629" Approved Supported Nucleoplasm Yes No "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB011581: AB_732529, HPA066629: AB_2685695" "unprognostic (1.90e-1)" "unprognostic (1.14e-1)" "unprognostic (1.11e-1)" "unprognostic (4.48e-2)" "unprognostic (1.51e-1)" "unprognostic (1.72e-2)" "unprognostic (2.16e-1)" "unprognostic (9.43e-2)" "unprognostic (4.36e-2)" "unprognostic (3.47e-1)" "unprognostic (2.61e-1)" "unprognostic (8.45e-3)" "prognostic unfavorable (1.92e-9)" "unprognostic (8.75e-3)" "unprognostic (2.07e-1)" "unprognostic (1.91e-1)" "unprognostic (2.12e-2)" 22.2 57.8 0.0 2.5 0.2 0.0 3.8 0.0 0.3 4.9 2.8 11.4 22.8 19.8 1.2 0.8 28.9 11.1 43.9 0.1 0.0 3.0 12.6 14.8 1.9 0.1 0.0 73.0 22.7 0.3 0.6 6.5 0.0 5.5 11.0 0.1 0.8 0.7 0.8 1.5 20.7 9.5 0.2 15.0 49.6 6.3 0.1 0.4 5.3 0.6 0.2 23.0 3.2 0.0 10.1 1.4 0.0 0.0 2.1 1.0 54.8 0.3 0.4 0.8 1.0 69.7 3.8 0.0 3.2 1.2 3.4 10.8 0.4 4.5 1.4 0.0 13.6 0.0 4.3 6.1 14.3 0.6 0.6 0.4 8.9 12.1 9.1 25.5 9.5 0.0 0.5 0.0 0.0 1.5 0.0 0.2 0.1 37.6 9.8 0.0 1.1 0.2 0.4 2.8 0.9 0.1 10.7 6.1 3.0 2.7 1.7 0.0 0.7 1.4 1.6 11.4 1.7 0.0 0.0 0.0 6.2 0.3 9.9 4.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 7.3 44.8 30.2 0.0 0.0 0.9 4.0 4.6 1.8 0.0 3.4 2.7 97.6 30.0 6.1 0.0 0.0 0.9 0.9 50.0 0.0 28.4 44.7 6.3 6.3 11.5 26.0 2.7 0.1 19.6 11.2 24.4 100.9 16.6 5.1 52.9 28.5 11.1 1.6 0.0 0.1 45.8 2.0 0.6 0.9 8.8 3.4 0.5 0.0 1.0 0.0 0.0 0.0 0.0 0.2 36.8 27.7 10.1 0.2 4.1 43.3 0.0 3.9 0.0 32.9 0.4 8.6 1.4 1.4 0.9 0.9 1.9 1.3 11.4 47.2 2.9 GATAD1 "FLJ22489, ODAG, RG083M05.2" ENSG00000157259 "GATA zinc finger domain containing 1" Q8WUU5 7 92447482-92460075 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 234.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006105, HPA072785" Enhanced Nucleoplasm Yes No "Cluster 17: Basophils - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA006105: AB_1078956, HPA072785: AB_2686556" "unprognostic (8.37e-2)" "unprognostic (1.01e-1)" "unprognostic (7.31e-3)" "unprognostic (6.24e-2)" "unprognostic (6.03e-2)" "unprognostic (1.36e-1)" "unprognostic (8.65e-3)" "unprognostic (6.43e-2)" "unprognostic (5.16e-2)" "unprognostic (4.30e-2)" "unprognostic (2.18e-1)" "unprognostic (2.16e-1)" "unprognostic (9.91e-2)" "unprognostic (2.93e-1)" "unprognostic (1.36e-1)" "unprognostic (3.44e-2)" "unprognostic (1.98e-3)" 22.7 22.1 9.5 7.3 12.8 6.2 22.2 10.1 10.9 26.8 9.7 22.3 11.2 21.4 18.3 14.6 26.5 11.8 16.2 9.6 10.5 21.4 20.1 20.1 8.7 12.1 11.5 33.6 29.4 15.5 23.1 12.4 12.4 23.9 11.3 13.2 18.4 12.4 10.8 14.0 18.6 11.7 10.4 20.2 21.6 10.2 12.0 6.7 26.0 5.7 7.3 22.0 20.2 16.0 12.3 7.5 15.3 16.1 19.7 22.4 12.1 11.9 17.8 12.4 16.9 8.5 18.5 9.1 15.9 8.9 28.9 14.3 10.7 8.1 13.0 15.8 11.3 11.6 8.0 11.6 27.4 14.1 30.0 16.8 19.3 9.5 27.4 22.3 14.2 6.6 24.2 19.0 13.8 17.7 5.5 20.2 20.8 19.9 14.4 7.2 18.1 12.1 13.6 13.4 13.4 21.4 15.7 16.5 23.7 19.0 9.2 18.8 13.0 19.7 14.9 30.0 15.5 15.2 5.5 10.0 16.6 9.0 27.6 2.9 1.1 1.2 0.7 0.7 0.7 0.9 0.5 0.5 0.6 1.4 0.6 0.9 1.0 0.9 0.8 1.2 0.6 0.4 9.5 12.8 10.1 10.9 9.6 10.5 12.1 11.5 12.4 10.4 12.0 16.0 59.0 48.1 64.6 98.9 26.5 13.3 37.8 14.6 26.7 79.0 33.3 35.1 16.3 24.3 26.6 47.8 70.9 25.7 28.8 30.2 3.9 22.4 3.8 46.7 48.3 34.7 16.8 24.6 77.8 22.0 23.4 38.1 30.5 51.6 53.2 115.1 37.1 21.7 24.6 62.2 70.4 33.3 2.0 30.8 23.7 5.0 45.4 40.2 21.4 54.4 25.8 65.3 32.0 108.6 234.9 27.0 30.7 35.0 13.6 45.9 33.2 18.2 36.1 114.1 19.7 54.3 36.7 14.1 10.4 23.6 17.8 20.7 24.7 56.0 31.9 35.7 GBX2 ENSG00000168505 "Gastrulation brain homeobox 2" P52951 2 236165236-236168386 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 58 "brain: 14.3" "Cell type enriched" "Detected in single" 4 "Early spermatids: 2.8" "Group enriched" "Detected in some" 6 "glioma: 1.7;testis cancer: 6.6" "Region enhanced" "Detected in many" "thalamus: 14.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 47.5;BEWO: 8.3;PC-3: 14.2;TIME: 7.7" "Region enhanced" "Detected in single" "thalamus: 1.3" "Group enriched" "Detected in some" 4 "midbrain: 2.5;pons: 2.7;thalamus: 6.4" HPA067809 Approved Nucleoplasm Yes NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "HPA067809: AB_2685900" "unprognostic (5.30e-2)" "unprognostic (1.15e-1)" "unprognostic (7.09e-2)" "unprognostic (1.59e-1)" "unprognostic (2.91e-2)" "unprognostic (4.49e-2)" "unprognostic (2.14e-2)" "unprognostic (1.72e-2)" "unprognostic (2.91e-1)" "unprognostic (8.13e-2)" "unprognostic (6.99e-2)" "unprognostic (3.55e-4)" "unprognostic (8.69e-7)" "unprognostic (2.08e-1)" "unprognostic (1.01e-2)" "unprognostic (5.47e-2)" "unprognostic (9.39e-4)" 0.0 0.0 1.5 0.0 1.8 0.0 0.0 2.0 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.7 0.0 0.0 0.0 0.0 4.9 5.3 0.0 0.0 0.0 0.1 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.2 14.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 2.6 0.9 47.5 1.8 0.0 0.0 8.3 0.7 0.0 1.3 0.0 1.1 0.0 0.0 0.9 0.0 1.4 0.0 0.4 0.1 0.3 0.0 4.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 3.9 0.0 3.4 0.0 0.6 1.2 0.0 0.4 1.2 0.0 14.2 0.0 5.1 0.0 0.4 0.0 0.6 0.3 1.6 0.0 0.5 1.5 0.0 0.0 7.7 0.4 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.8 2.0 1.2 0.4 2.7 4.9 5.3 3.6 3.0 14.3 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 GCAT KBL ENSG00000100116 "Glycine C-acetyltransferase" O75600 22 37807905-37817176 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 140.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 80.3;Hepatocytes: 66.1;Proximal tubular cells: 163.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020460, HPA063924" Approved Supported "Nucleoplasm,Nuclear speckles,Mitochondria" Yes No "Cluster 20: T-cells - T-cell receptor" "Cluster 22: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Nuclear speckles, Mitochondria" "HPA020460: AB_1849548, HPA063924: " "unprognostic (1.61e-1)" "unprognostic (1.80e-2)" "unprognostic (8.38e-2)" "unprognostic (1.05e-1)" "unprognostic (1.10e-2)" "unprognostic (4.17e-2)" "unprognostic (2.40e-1)" "unprognostic (1.37e-2)" "unprognostic (3.56e-2)" "unprognostic (2.76e-3)" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (1.36e-3)" "unprognostic (8.00e-2)" "unprognostic (1.97e-1)" "unprognostic (4.73e-3)" "unprognostic (3.99e-1)" 6.6 15.7 25.1 3.2 24.8 14.1 6.5 26.2 33.3 6.3 22.5 7.3 4.9 7.8 3.0 17.0 6.0 5.0 43.4 26.1 25.0 13.0 53.3 5.6 2.8 25.9 27.4 9.0 140.2 6.0 9.7 2.7 27.8 22.8 4.9 2.2 13.3 6.8 19.5 8.1 5.4 4.2 24.4 1.5 13.2 10.3 27.9 4.3 16.0 19.1 3.1 7.1 7.0 24.6 18.7 4.7 11.9 68.2 24.0 19.4 8.4 25.9 26.9 19.2 16.3 10.5 2.1 5.8 11.8 11.7 11.3 10.6 11.9 18.3 4.3 2.6 21.9 12.9 15.0 42.5 39.0 23.0 16.4 22.8 10.9 12.7 27.7 6.2 16.0 23.0 33.2 6.6 9.2 16.2 24.3 42.3 5.0 28.8 19.0 25.2 2.5 34.4 24.6 14.3 24.5 16.7 20.0 32.3 13.9 4.2 25.8 11.1 11.8 19.3 10.6 12.9 9.2 21.9 11.5 12.1 13.3 21.1 20.5 0.1 0.6 0.4 0.7 0.7 0.3 0.1 1.6 0.5 1.3 0.0 3.5 1.4 0.3 1.3 0.4 1.3 1.7 1.4 25.1 24.8 26.2 33.3 26.1 25.0 25.9 27.4 27.8 24.4 27.9 24.6 3.5 6.4 15.4 9.8 2.8 7.8 18.5 11.2 12.5 8.9 18.6 17.4 54.6 11.5 9.4 11.0 4.2 15.7 0.7 13.1 80.3 7.2 4.1 9.9 8.1 5.5 2.4 22.7 5.0 10.3 19.6 9.8 15.3 16.7 8.9 17.6 5.0 66.1 4.7 8.4 4.7 32.3 8.2 2.9 1.3 7.7 3.7 2.1 21.4 1.0 1.0 25.1 1.0 6.6 4.1 5.4 8.7 9.8 2.0 19.1 8.6 163.8 6.4 2.2 6.6 4.8 30.1 12.6 33.2 19.6 6.0 27.8 3.0 27.8 24.0 14.4 GDAP2 "dJ776P7.1, FLJ20142, MACROD3" ENSG00000196505 "Ganglioside induced differentiation associated protein 2" Q9NXN4 1 117863485-117929621 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046185 Approved Approved "Endoplasmic reticulum" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 59: Non-specific - Transcription" "Endoplasmic reticulum" "HPA046185: AB_10960897" "unprognostic (4.12e-2)" "unprognostic (1.40e-1)" "unprognostic (2.64e-1)" "unprognostic (1.82e-2)" "unprognostic (4.33e-2)" "unprognostic (1.05e-1)" "unprognostic (1.53e-3)" "unprognostic (1.25e-1)" "unprognostic (2.60e-1)" "unprognostic (4.26e-3)" "unprognostic (2.26e-3)" "unprognostic (6.38e-2)" "unprognostic (1.18e-1)" "unprognostic (4.09e-2)" "unprognostic (3.28e-2)" "unprognostic (8.68e-2)" "unprognostic (1.68e-1)" 3.0 2.4 2.3 3.2 2.1 8.0 3.2 3.6 2.7 3.4 3.4 3.8 4.0 2.8 4.0 3.1 2.4 3.2 2.5 2.0 2.3 4.8 5.1 3.4 3.6 2.1 2.6 2.4 4.5 4.9 2.3 4.1 2.4 3.4 4.4 2.9 3.0 3.3 1.8 2.9 4.7 3.0 2.4 4.2 4.4 4.8 2.7 4.1 4.6 2.1 4.4 4.5 3.1 2.9 9.2 5.1 6.1 5.1 6.5 3.1 9.0 5.2 6.8 10.3 9.9 5.4 6.2 3.6 6.2 7.1 7.8 5.3 8.1 6.8 12.6 7.2 4.7 5.4 6.7 5.9 7.7 6.8 6.6 2.5 8.5 12.9 9.9 4.7 6.9 8.1 5.7 7.6 8.6 9.6 6.0 5.5 10.6 6.9 8.8 3.2 16.7 5.3 5.8 9.1 4.6 5.1 6.3 10.7 8.2 18.3 3.7 6.8 4.3 7.3 8.5 8.5 7.1 7.9 6.1 5.1 9.4 4.8 9.1 11.4 6.7 12.6 2.4 7.2 3.8 2.3 2.7 2.9 6.5 2.2 2.4 2.3 6.5 4.1 7.6 1.5 3.6 3.2 2.3 2.1 3.6 2.7 2.0 2.3 2.1 2.6 2.4 2.4 2.7 2.9 9.2 9.6 8.6 27.7 13.5 13.5 6.5 8.1 8.6 13.1 8.1 5.5 7.8 8.6 10.8 3.7 18.8 12.4 11.6 13.4 7.9 10.6 21.2 12.8 9.0 7.6 4.2 13.9 36.7 6.2 11.4 7.7 18.3 11.5 0.0 10.4 6.4 9.0 13.8 15.2 39.1 14.0 14.2 17.2 15.8 5.7 5.9 20.0 10.6 34.7 16.2 9.2 8.2 31.7 35.8 10.7 7.5 7.2 21.0 9.8 17.8 10.2 10.5 13.7 0.0 8.6 10.2 28.4 14.5 14.3 13.8 21.1 13.8 6.7 8.3 9.6 GDPD3 MGC4171 ENSG00000102886 "Glycerophosphodiester phosphodiesterase domain containing 3" Q7L5L3 16 30104810-30113537 "Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 45.6" "Cell type enriched" "Detected in many" 4 "Late spermatids: 447.4" "Cancer enhanced" "Detected in all" "urothelial cancer: 21.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.4" "Lineage enriched" "Detected in single" 22 "granulocytes: 2.4" "Cell line enhanced" "Detected in many" "Hep G2: 32.1;MCF7: 50.6;OE19: 53.3;SK-BR-3: 165.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041148, HPA041470" Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA041148: AB_10794545, HPA041470: AB_10795121" "unprognostic (4.12e-1)" "unprognostic (2.29e-2)" "unprognostic (2.01e-1)" "unprognostic (9.99e-2)" "unprognostic (2.53e-1)" "unprognostic (4.57e-3)" "unprognostic (1.09e-1)" "unprognostic (1.36e-1)" "unprognostic (4.53e-1)" "unprognostic (8.86e-3)" "unprognostic (6.59e-3)" "unprognostic (1.95e-1)" "prognostic unfavorable (5.89e-9)" "unprognostic (3.11e-1)" "unprognostic (3.13e-1)" "unprognostic (1.12e-1)" "unprognostic (8.79e-3)" 7.1 2.4 6.1 6.0 6.1 1.8 5.4 6.8 11.4 18.7 5.9 25.9 8.4 5.3 9.3 45.6 5.7 2.5 5.2 6.0 6.1 17.9 2.1 6.4 4.2 7.5 6.1 6.8 2.2 0.4 4.8 11.4 8.0 5.7 17.2 6.5 9.0 2.2 2.1 11.0 10.2 5.2 6.3 9.0 18.8 1.8 6.1 4.1 4.7 0.9 20.9 5.4 19.1 6.8 21.8 0.3 5.2 1.5 1.6 5.5 5.5 0.6 1.3 1.8 1.7 1.0 15.2 0.6 2.9 1.5 0.6 1.8 1.6 0.5 1.8 2.5 4.0 0.2 1.0 32.1 1.0 0.7 1.3 0.2 1.6 4.5 0.3 4.1 5.1 4.2 1.0 2.3 2.2 50.6 1.5 2.0 2.6 53.3 0.6 6.3 1.4 7.1 2.6 7.4 1.1 2.2 0.2 165.0 0.5 1.6 3.0 2.7 2.7 0.9 1.1 1.9 1.8 2.7 0.9 1.5 4.2 2.7 0.7 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.1 0.0 6.1 6.1 6.8 11.4 6.0 6.1 7.5 6.1 8.0 6.3 6.1 6.8 5.9 6.4 1.1 1.6 1.0 1.3 0.9 4.4 1.2 1.6 4.1 3.0 1.5 0.0 22.2 5.5 0.0 24.2 1.2 98.2 5.9 0.9 67.8 2.6 3.8 4.3 3.5 0.0 0.6 1.3 71.9 2.1 30.1 4.1 0.0 2.0 3.9 0.3 3.1 1.7 0.8 34.2 6.1 1.9 1.0 447.4 3.4 1.4 1.8 1.9 1.2 0.6 0.0 1.5 1.2 19.2 36.7 3.0 0.1 1.1 46.0 100.6 9.0 1.7 6.6 0.6 2.7 1.4 1.3 5.1 2.0 9.3 1.9 1.3 13.9 4.8 GET4 "C7orf20, CEE, CGI-20, H_NH1244M04.5, TRC35" ENSG00000239857 "Guided entry of tail-anchored proteins factor 4" Q7L5D6 7 876554-896436 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 36.7;Oligodendrocytes: 15.8;Plasma cells: 37.2;Squamous epithelial cells: 23.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019765 Uncertain Enhanced "Nucleoplasm,Nucleoli,Mitotic chromosome,Cytosol" Yes No "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Cytosol" "Nucleoli, Mitotic chromosome" "HPA019765: AB_1845750" "unprognostic (2.80e-2)" "unprognostic (2.40e-2)" "unprognostic (2.10e-2)" "unprognostic (9.66e-4)" "unprognostic (9.86e-2)" "unprognostic (8.64e-2)" "unprognostic (4.10e-2)" "unprognostic (1.74e-1)" "unprognostic (2.59e-1)" "unprognostic (6.28e-2)" "unprognostic (2.43e-1)" "unprognostic (1.21e-1)" "unprognostic (7.65e-2)" "unprognostic (8.18e-2)" "unprognostic (1.26e-1)" "unprognostic (5.93e-2)" "unprognostic (9.47e-2)" 25.0 98.0 28.9 12.5 33.7 31.6 26.8 29.7 37.0 28.1 19.1 33.5 20.8 25.5 21.1 43.7 32.1 11.4 33.1 28.8 31.1 68.8 98.4 25.5 15.8 36.1 33.4 34.3 46.1 13.7 70.7 20.5 36.0 37.8 8.8 16.4 28.8 12.3 56.3 46.9 33.6 7.7 29.1 37.5 41.5 79.0 34.0 14.4 34.3 21.9 10.4 31.3 28.9 45.6 78.8 38.1 25.8 38.4 13.2 9.1 81.7 21.2 14.9 26.5 26.6 103.4 95.1 28.5 21.7 12.4 73.7 48.7 29.3 23.3 11.5 11.6 50.9 15.8 31.5 59.5 29.1 27.1 28.1 13.8 27.6 23.4 15.1 19.9 21.1 32.5 103.6 25.7 15.2 59.7 20.8 65.2 93.3 46.1 56.0 43.0 4.5 30.8 23.8 45.4 46.7 50.5 19.5 71.2 32.2 31.5 54.2 47.8 21.4 19.6 43.6 45.7 29.5 38.5 25.9 37.5 20.1 46.2 50.3 22.3 28.5 32.4 23.9 27.6 23.3 24.3 26.4 24.1 29.4 24.5 25.2 27.0 21.9 27.7 35.3 33.3 26.9 24.8 28.9 33.7 29.7 37.0 28.8 31.1 36.1 33.4 36.0 29.1 34.0 45.6 0.3 0.0 3.1 14.7 10.6 1.0 0.3 0.2 14.8 0.8 1.1 0.9 0.6 0.0 2.2 0.0 4.2 1.1 0.7 2.3 0.0 0.9 4.0 2.0 1.1 1.5 0.0 9.2 9.1 0.7 0.7 3.8 36.7 2.8 1.3 1.2 0.0 0.4 0.6 8.4 9.1 2.8 0.0 0.6 0.8 2.7 0.0 6.1 0.0 4.7 0.5 0.2 0.0 10.1 15.8 0.8 1.0 0.0 37.2 0.4 3.6 1.1 2.1 1.4 0.0 0.8 1.8 0.6 1.1 23.5 1.0 1.6 9.9 0.8 1.7 0.8 GFM2 "EF-G2mt, EFG2, FLJ21661" ENSG00000164347 "GTP dependent ribosome recycling factor mitochondrial 2" Q969S9 5 74721206-74767147 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Protein biosynthesis" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 61.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036863, HPA069871" Uncertain Approved "Nucleoplasm,Midbody ring,Mitochondria" Yes NA "Cluster 11: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "Nucleoplasm, Midbody ring" "HPA036863: AB_2675354, HPA069871: " "unprognostic (2.58e-3)" "unprognostic (7.04e-2)" "unprognostic (8.54e-3)" "unprognostic (1.98e-1)" "unprognostic (4.49e-2)" "unprognostic (2.05e-2)" "unprognostic (1.73e-1)" "unprognostic (1.64e-1)" "unprognostic (1.40e-1)" "unprognostic (3.80e-2)" "unprognostic (2.10e-2)" "unprognostic (1.29e-1)" "prognostic favorable (1.33e-5)" "unprognostic (9.55e-2)" "unprognostic (4.15e-1)" "unprognostic (8.52e-3)" "unprognostic (9.82e-2)" 9.6 18.1 9.7 10.2 10.5 15.0 14.1 10.2 14.5 10.7 16.1 13.9 9.3 11.1 17.4 11.9 23.4 9.0 33.3 10.8 10.7 23.3 34.0 9.0 12.2 9.5 9.1 11.4 10.0 30.4 10.7 13.5 10.0 13.0 15.8 16.8 13.4 11.2 30.6 11.3 10.8 10.8 9.4 8.5 17.9 15.8 10.2 17.2 13.1 38.5 15.5 12.9 7.0 11.1 39.5 34.3 27.2 52.2 20.3 27.1 28.2 41.5 24.7 41.5 44.1 36.4 24.9 39.7 44.9 21.9 65.7 32.1 55.0 59.6 54.8 34.8 35.5 22.9 31.7 27.0 27.1 23.6 26.0 32.1 26.3 33.6 40.5 29.8 30.3 39.4 40.7 32.9 48.5 23.3 32.1 15.1 11.4 14.8 29.7 41.1 43.5 49.3 32.0 24.7 46.6 24.8 46.3 38.1 44.3 30.1 33.0 44.0 24.0 16.2 27.8 20.5 27.2 19.0 38.3 40.1 24.1 34.2 24.6 22.8 6.9 9.2 6.7 7.2 6.6 8.3 5.5 7.5 6.7 7.2 7.5 7.3 3.5 16.0 11.8 4.4 7.0 5.2 9.7 10.5 10.2 14.5 10.8 10.7 9.5 9.1 10.0 9.4 10.2 11.1 6.4 12.8 12.9 19.9 8.5 6.0 7.1 13.0 8.6 9.1 7.7 6.9 11.0 7.2 12.5 7.3 6.2 20.1 7.5 8.9 21.5 9.5 11.5 42.4 9.2 6.4 5.4 17.9 35.7 5.3 15.9 6.3 15.3 13.7 2.5 10.4 5.3 22.4 9.9 16.8 34.1 9.7 30.5 8.5 2.4 2.6 7.2 6.8 8.8 13.1 17.9 13.0 7.2 34.2 29.1 9.8 9.9 7.5 11.4 4.6 8.5 11.2 61.5 9.6 0.0 5.6 7.8 15.2 11.7 10.0 7.0 16.0 7.3 11.1 10.0 7.5 GFUS "FX, P35B, SDR4E1, TSTA3" ENSG00000104522 "GDP-L-fucose synthase" Q13630 8 143612618-143618048 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 32.1;Cytotrophoblasts: 82.1;Extravillous trophoblasts: 156.4;Hofbauer cells: 69.9;Syncytiotrophoblasts: 87.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023361 Approved Approved Nucleoplasm,Cytosol Yes No 850000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "HPA023361: AB_1858420" "unprognostic (1.37e-2)" "unprognostic (5.35e-2)" "unprognostic (8.62e-3)" "unprognostic (3.55e-2)" "unprognostic (2.90e-1)" "unprognostic (5.82e-2)" "unprognostic (2.48e-2)" "unprognostic (1.98e-1)" "unprognostic (8.62e-2)" "prognostic favorable (2.41e-4)" "unprognostic (6.62e-3)" "unprognostic (6.89e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (4.23e-2)" "unprognostic (2.78e-2)" "unprognostic (1.87e-2)" "unprognostic (3.27e-2)" 36.3 37.2 21.6 27.7 21.1 52.3 34.0 21.4 25.9 28.6 21.7 45.9 69.2 24.8 19.2 88.7 24.0 29.3 32.1 20.7 21.3 37.5 86.6 28.4 29.1 23.5 21.9 19.0 99.5 22.8 44.0 24.4 22.8 45.0 37.6 6.5 70.9 24.2 30.2 81.5 52.4 19.4 20.2 35.7 111.4 49.4 21.0 26.6 32.1 18.4 27.1 31.0 36.0 22.5 85.6 67.1 29.2 99.7 28.6 26.1 54.1 70.3 73.0 50.2 38.1 78.5 94.3 37.5 64.6 52.5 21.2 60.6 47.8 100.8 23.2 101.7 53.8 58.7 103.0 93.4 57.2 42.2 67.1 30.3 47.4 31.7 127.3 42.2 84.3 61.9 66.4 57.0 41.2 267.5 39.8 53.2 45.8 267.7 87.1 47.1 26.3 122.3 106.1 94.8 67.3 45.9 53.3 100.2 73.0 23.0 133.5 58.8 75.5 34.8 132.0 35.1 67.6 34.1 30.2 29.0 52.8 91.6 54.7 34.9 27.4 42.9 40.3 38.5 43.0 35.2 43.1 46.8 30.1 40.1 31.5 38.5 31.0 63.6 33.8 54.5 57.5 45.7 21.6 21.1 21.4 25.9 20.7 21.3 23.5 21.9 22.8 20.2 21.0 22.5 32.1 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 82.1 11.2 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 156.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 69.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 87.7 1.7 0.0 0.0 0.0 GLI4 "HKR4, ZNF928" ENSG00000250571 "GLI family zinc finger 4" P10075 8 143267433-143276931 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023131 Uncertain Approved "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 40: NK-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Cytokinetic bridge" "HPA023131: AB_2671080" "unprognostic (4.98e-2)" "unprognostic (2.69e-1)" "unprognostic (5.64e-3)" "unprognostic (1.65e-1)" "unprognostic (9.07e-2)" "unprognostic (2.71e-2)" "unprognostic (1.00e-2)" "unprognostic (4.57e-2)" "unprognostic (2.22e-1)" "unprognostic (2.65e-1)" "unprognostic (7.45e-3)" "unprognostic (5.03e-1)" "unprognostic (6.88e-3)" "unprognostic (4.61e-2)" "unprognostic (1.23e-1)" "unprognostic (3.21e-2)" "unprognostic (3.71e-3)" 11.6 6.6 8.8 4.7 8.2 5.8 10.7 8.3 15.4 12.3 3.3 10.8 6.4 10.3 2.1 12.8 10.2 2.7 13.0 9.6 7.1 13.7 12.0 6.9 5.6 7.4 6.8 13.4 12.6 4.6 9.3 2.0 7.5 13.4 3.7 2.5 9.2 3.9 9.2 12.9 10.4 1.8 5.1 11.6 11.5 10.4 7.5 5.5 10.1 2.0 4.8 11.3 11.1 7.2 6.7 13.5 6.2 9.9 9.9 4.1 7.0 3.9 2.3 2.9 3.5 3.9 19.1 8.7 7.2 6.5 4.2 8.7 3.4 4.3 1.9 15.3 10.3 13.4 7.1 4.6 7.1 4.2 4.3 12.9 2.3 4.0 8.5 6.7 6.4 13.2 7.2 14.1 8.0 18.5 19.7 3.5 5.8 12.8 19.0 11.9 2.9 8.8 7.0 15.0 6.0 7.0 11.7 5.0 8.2 5.7 22.1 1.9 3.6 4.3 12.1 6.2 4.1 18.6 9.7 7.0 7.0 8.0 7.3 0.0 0.3 0.0 0.3 0.3 0.6 0.4 0.4 0.2 0.1 0.3 0.6 0.2 0.3 1.1 0.0 1.1 0.6 0.2 8.8 8.2 8.3 15.4 9.6 7.1 7.4 6.8 7.5 5.1 7.5 7.2 9.5 0.0 0.0 13.1 11.2 7.4 12.7 1.3 13.6 14.6 10.9 12.2 2.0 12.8 1.1 12.9 20.9 5.0 20.6 15.4 25.4 2.6 6.3 8.2 10.6 6.8 11.5 5.9 7.2 4.0 4.5 9.5 11.7 7.3 4.5 15.8 8.9 7.7 7.2 6.7 8.4 7.6 2.0 10.1 5.7 4.3 16.1 9.9 8.8 12.2 6.9 11.9 13.4 4.5 15.5 3.6 17.9 16.6 8.8 9.4 16.4 20.1 2.3 11.9 6.6 11.2 10.6 13.4 14.7 15.8 10.7 2.9 11.9 14.6 13.7 9.9 GMNN Gem ENSG00000112312 "Geminin DNA replication inhibitor" O75496 6 24774931-24786099 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "DNA replication inhibitor" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 231.4" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 184.8;Paneth cells: 300.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011458, CAB047327, CAB047328, HPA049977, HPA054597" Enhanced Supported Nucleoplasm,Cytosol Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 25: Pancreas - Digestion" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "CAB011458: AB_2110946, CAB047327: , CAB047328: , HPA049977: AB_2680978, HPA054597: AB_2682538" "unprognostic (1.37e-1)" "unprognostic (3.43e-3)" "unprognostic (3.91e-3)" "unprognostic (1.52e-2)" "unprognostic (1.28e-1)" "unprognostic (4.37e-2)" "unprognostic (2.90e-3)" "unprognostic (8.29e-2)" "unprognostic (1.23e-3)" "prognostic favorable (4.13e-4)" "prognostic unfavorable (9.77e-4)" "unprognostic (1.33e-2)" "prognostic unfavorable (7.82e-5)" "unprognostic (2.25e-1)" "unprognostic (7.92e-2)" "unprognostic (3.63e-2)" "unprognostic (5.90e-3)" 10.1 7.7 16.9 17.2 18.2 68.9 24.2 19.5 23.7 11.1 13.5 41.6 17.8 10.6 5.8 16.6 16.5 7.9 8.0 14.7 20.2 24.6 18.2 8.9 30.4 17.0 20.2 14.6 231.4 8.4 11.1 16.5 17.8 41.5 44.4 16.3 8.7 24.9 7.4 40.3 16.1 12.5 16.4 19.1 22.6 37.4 19.8 37.4 10.8 14.3 23.7 28.4 13.9 15.5 110.9 64.2 159.2 66.2 22.2 23.5 106.0 106.0 55.9 124.4 135.5 125.1 38.8 110.1 131.3 34.4 91.3 63.3 139.4 78.1 133.0 41.2 145.4 151.5 109.3 207.4 20.7 119.1 53.1 19.1 25.1 75.9 29.5 25.8 62.2 84.6 193.9 56.9 88.9 86.3 224.9 128.2 87.3 89.6 50.2 128.9 124.4 141.2 53.5 94.6 127.3 78.3 47.5 77.4 95.2 89.1 81.3 72.0 30.9 75.7 76.8 88.3 182.6 62.8 207.6 210.3 23.1 220.9 111.2 5.5 5.2 17.1 4.4 6.9 5.6 9.2 8.5 6.9 7.6 4.6 6.1 6.9 3.0 5.9 5.0 9.4 15.9 5.6 16.9 18.2 19.5 23.7 14.7 20.2 17.0 20.2 17.8 16.4 19.8 15.5 24.0 6.4 15.6 8.8 17.0 33.0 28.4 57.4 18.8 9.5 51.0 52.5 12.1 18.6 68.1 44.1 2.1 83.2 19.9 72.6 9.8 113.6 94.8 84.8 30.6 18.4 25.9 66.2 3.5 112.3 136.3 17.7 12.2 184.8 13.3 36.4 13.9 17.4 54.0 11.8 5.3 66.3 10.2 10.7 13.2 28.0 9.6 15.2 23.2 5.6 12.6 30.9 6.2 5.5 3.2 31.8 300.5 10.9 41.6 25.6 20.8 20.6 25.2 13.7 19.7 8.0 21.9 158.8 58.8 26.8 63.5 48.7 19.1 30.4 156.5 30.1 GNL3 "C77032, E2IG3, MGC800, NS" ENSG00000163938 "G protein nucleolar 3" Q9BVP2 3 52681156-52694497 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020770, HPA036742, HPA036743" Enhanced Enhanced "Nucleoli rim,Nuclear bodies,Mitotic chromosome" Yes No 13000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli rim" "Nuclear bodies, Mitotic chromosome" "CAB020770: , HPA036742: AB_2675282, HPA036743: AB_2675283" "unprognostic (4.40e-1)" "unprognostic (9.30e-2)" "unprognostic (4.10e-3)" "unprognostic (2.21e-1)" "unprognostic (5.11e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.93e-4)" "unprognostic (1.46e-1)" "unprognostic (3.29e-3)" "unprognostic (1.14e-2)" "unprognostic (1.67e-3)" "prognostic unfavorable (6.11e-4)" "prognostic unfavorable (5.69e-5)" "unprognostic (1.33e-1)" "unprognostic (9.25e-2)" "unprognostic (1.03e-3)" "unprognostic (1.06e-2)" 47.2 47.1 17.1 42.1 17.0 27.4 68.8 18.4 24.4 38.8 18.7 40.0 38.8 33.8 25.6 65.0 28.2 28.0 29.6 17.9 19.4 33.4 50.3 29.7 51.5 17.9 17.7 35.8 60.7 27.1 35.9 36.4 17.8 46.7 46.0 16.0 46.4 26.3 78.2 39.1 29.6 32.2 16.9 34.0 41.0 26.8 17.9 35.9 28.6 42.9 64.9 92.3 41.3 19.1 110.4 79.1 114.4 125.3 105.6 105.1 178.1 133.0 101.5 135.4 100.6 121.3 80.8 255.4 42.2 100.1 104.6 78.2 189.1 125.1 180.5 156.3 134.6 196.8 139.0 189.3 218.1 283.7 138.0 96.1 216.5 147.8 224.1 90.3 107.8 99.7 214.8 136.2 93.8 77.7 170.6 162.1 195.6 153.4 151.2 99.3 93.0 315.0 108.9 153.9 81.4 105.6 82.1 190.5 193.6 101.7 74.7 155.8 86.6 92.8 100.0 139.2 281.7 147.6 252.0 387.0 96.9 203.5 148.4 1.2 15.2 3.3 19.9 16.7 34.1 28.7 26.8 24.1 26.1 23.9 30.4 29.4 1.8 26.1 12.9 40.7 18.8 20.2 17.1 17.0 18.4 24.4 17.9 19.4 17.9 17.7 17.8 16.9 17.9 19.1 34.6 22.4 48.2 5.2 84.3 163.7 146.0 111.9 77.4 19.0 72.6 46.4 51.3 25.8 144.9 12.9 10.4 73.2 78.5 42.8 41.1 105.1 54.4 44.7 76.5 53.4 47.8 51.5 11.6 104.6 117.5 92.9 47.9 53.0 63.1 47.5 23.2 41.9 40.9 21.9 11.1 71.7 67.1 24.2 77.6 28.2 51.9 43.0 78.2 5.6 59.5 17.7 38.1 7.1 9.4 99.9 34.4 34.3 122.3 126.1 19.1 47.2 56.5 14.8 6.6 106.2 79.1 37.9 74.4 59.4 153.7 90.3 63.0 74.5 85.8 135.7 GPN3 "ATPBD1C, MGC14560" ENSG00000111231 "GPN-loop GTPase 3" Q9UHW5 12 110452486-110469268 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 187.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039764, HPA047793" Uncertain Approved "Nuclear speckles,Cytosol" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" Cytosol "HPA039764: AB_2676669, HPA047793: AB_2680157" "unprognostic (1.68e-3)" "unprognostic (1.11e-2)" "unprognostic (9.82e-2)" "unprognostic (4.96e-2)" "unprognostic (2.09e-1)" "unprognostic (3.27e-3)" "prognostic unfavorable (3.98e-5)" "unprognostic (5.50e-2)" "unprognostic (4.45e-2)" "unprognostic (2.70e-1)" "unprognostic (1.24e-1)" "unprognostic (3.56e-2)" "prognostic favorable (2.65e-6)" "unprognostic (5.81e-2)" "unprognostic (2.85e-1)" "unprognostic (1.62e-1)" "unprognostic (2.27e-1)" 25.6 18.9 10.4 16.3 11.7 15.4 24.4 12.9 12.9 15.7 11.6 15.6 8.1 17.8 15.2 16.3 18.5 13.8 34.2 10.0 11.0 31.4 32.1 16.9 22.9 12.2 11.2 23.3 19.9 29.2 11.1 21.3 12.8 22.2 13.1 23.4 24.2 18.0 47.9 11.1 10.6 19.5 13.0 16.2 15.6 41.3 10.9 18.1 21.2 51.1 18.1 17.6 13.8 14.9 42.3 65.8 43.2 42.8 47.5 30.1 57.6 57.1 34.1 62.2 50.3 59.7 24.6 81.5 38.5 31.0 46.0 37.9 54.2 50.5 83.9 46.9 50.6 47.7 33.8 50.5 33.2 75.2 42.2 32.2 31.4 61.1 39.5 34.9 45.6 67.0 82.1 17.9 44.3 28.2 69.8 142.8 53.4 58.6 64.8 23.5 59.9 62.2 39.3 37.8 34.7 34.8 57.7 39.0 49.9 55.0 66.7 87.7 25.4 51.6 38.0 51.3 66.6 24.7 68.0 85.1 38.2 68.5 60.3 41.0 54.4 79.4 30.0 71.9 32.8 46.5 32.0 34.2 51.1 47.9 40.5 26.9 27.4 28.4 75.3 62.5 30.1 41.6 10.4 11.7 12.9 12.9 10.0 11.0 12.2 11.2 12.8 13.0 10.9 14.9 23.8 25.6 34.5 3.3 24.5 29.8 49.3 57.9 15.9 18.8 28.8 32.5 43.8 20.0 36.0 33.1 14.6 62.4 26.6 3.8 107.6 30.4 111.1 24.9 24.6 20.8 8.3 26.9 4.3 21.3 74.0 25.4 8.2 21.5 31.0 18.6 18.2 38.1 94.7 21.9 5.6 9.1 40.7 19.1 17.7 22.6 19.9 33.2 16.0 14.0 39.6 25.7 19.6 3.5 6.4 22.4 11.0 23.7 20.9 55.5 5.3 72.1 34.2 33.0 26.3 31.0 35.3 187.2 77.6 20.8 25.4 46.7 19.2 22.1 13.7 40.2 GPR161 RE2 ENSG00000143147 "G protein-coupled receptor 161" Q8N6U8 1 168079543-168137667 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 41.5;smooth muscle: 27.6" "Cell type enriched" "Detected in many" 8 "Horizontal cells: 158.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 44.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015576, HPA072047" Uncertain Uncertain Nucleoplasm,Nucleoli Yes No "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm Nucleoli "HPA015576: AB_1849283, HPA072047: AB_2686484" "unprognostic (1.45e-1)" "unprognostic (3.78e-2)" "unprognostic (2.68e-2)" "unprognostic (1.58e-3)" "unprognostic (1.87e-1)" "unprognostic (6.84e-2)" "unprognostic (3.24e-3)" "unprognostic (1.48e-1)" "unprognostic (1.19e-1)" "unprognostic (5.04e-2)" "unprognostic (5.45e-2)" "unprognostic (1.31e-2)" "unprognostic (5.57e-6)" "unprognostic (3.93e-2)" "unprognostic (1.84e-2)" "unprognostic (1.03e-2)" "unprognostic (6.34e-2)" 3.5 1.1 3.8 5.3 2.8 0.2 2.7 3.3 4.0 6.7 1.1 8.4 1.5 41.5 3.6 9.8 10.7 5.6 3.1 3.8 2.4 1.4 0.4 4.2 0.9 3.7 9.4 7.3 11.7 5.4 1.7 2.2 3.8 9.5 3.2 2.1 1.8 11.8 1.0 2.1 3.3 27.6 2.8 2.0 2.9 1.7 4.1 2.0 1.7 1.9 1.3 4.6 5.4 2.7 11.7 7.1 28.0 18.1 6.6 11.7 0.0 11.1 11.9 9.2 9.7 44.9 1.8 0.0 6.0 16.6 17.2 33.9 6.9 10.7 5.3 4.4 8.8 4.2 5.8 0.1 2.8 1.2 2.8 4.2 6.9 7.9 12.7 21.3 18.7 3.6 3.9 0.1 14.2 1.0 1.3 0.2 11.5 19.4 11.0 3.4 12.1 0.0 4.9 3.1 5.7 24.6 12.0 0.4 32.2 10.6 6.3 1.4 25.4 18.9 9.7 25.6 12.7 0.0 0.0 0.0 5.0 0.0 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.8 2.8 3.3 4.0 3.8 2.4 3.7 9.4 3.8 2.8 4.1 2.7 5.8 3.2 1.1 13.7 0.1 2.2 5.7 2.5 5.2 2.2 2.2 4.2 3.6 0.0 1.4 0.0 0.0 0.5 0.0 2.8 0.0 4.1 0.4 1.3 19.4 9.1 0.0 0.0 10.8 8.0 0.4 12.3 1.1 1.8 0.0 15.3 8.9 0.1 0.8 158.2 10.9 1.5 0.0 2.5 6.3 0.9 7.5 2.0 1.8 3.7 1.1 3.2 0.0 9.5 0.4 2.6 2.4 17.0 0.0 10.9 0.0 0.1 1.1 2.1 19.7 8.8 15.1 0.3 3.3 2.7 1.4 0.4 1.0 0.7 2.5 2.7 GPRIN2 "KIAA0514, MGC15171" ENSG00000204175 "G protein regulated inducer of neurite outgrowth 2" O60269 10 46549044-46555530 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 10.5;skin 1: 17.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 19.2;Distal enterocytes: 30.4;Exocrine glandular cells: 20.2;Intestinal goblet cells: 30.8;Late spermatids: 20.6;Proximal enterocytes: 21.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "A-431: 10.2;A549: 13.1;SiHa: 3.7;SK-BR-3: 12.0" "Low region specificity" "Detected in many" "HPA038129, HPA070760" Approved Approved "Plasma membrane,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane, Microtubules" "Cytokinetic bridge, Mitotic spindle" "HPA038129: AB_2675846, HPA070760: " "unprognostic (1.00e-2)" "unprognostic (1.91e-1)" "unprognostic (1.77e-2)" "prognostic unfavorable (8.60e-8)" "unprognostic (5.77e-2)" "prognostic favorable (3.47e-4)" "unprognostic (2.23e-1)" "unprognostic (2.67e-2)" "unprognostic (2.54e-1)" "unprognostic (1.27e-1)" "unprognostic (1.52e-2)" "unprognostic (1.45e-1)" "unprognostic (8.97e-2)" "unprognostic (1.98e-2)" "unprognostic (2.37e-1)" "unprognostic (1.23e-1)" "unprognostic (5.67e-3)" 0.1 0.0 1.7 0.6 1.6 0.0 0.9 5.9 2.1 0.9 0.4 6.2 3.6 0.0 0.0 4.4 0.3 0.2 0.0 0.6 6.7 5.7 0.3 10.5 0.0 5.5 4.9 0.1 5.7 2.1 4.2 0.0 5.7 1.9 3.4 0.1 2.8 1.1 0.1 17.4 8.0 0.1 1.8 0.0 5.1 3.0 9.7 0.0 3.4 0.0 0.5 0.6 2.0 1.0 10.2 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.2 0.0 0.7 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.9 0.0 0.0 0.0 0.0 1.7 0.3 0.3 0.1 3.7 12.0 0.0 1.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.6 5.9 2.1 0.6 6.7 5.5 4.9 5.7 1.8 9.7 1.0 0.0 19.2 3.7 0.0 0.0 1.7 2.8 1.9 2.8 0.3 1.4 1.0 0.2 7.2 2.1 3.7 0.0 0.0 0.0 30.4 0.0 11.3 9.3 0.0 0.0 0.1 6.6 0.0 0.7 20.2 0.0 0.1 3.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.9 30.8 0.0 0.0 0.3 20.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 12.6 13.1 0.4 0.0 2.1 21.7 4.0 1.8 0.1 0.0 0.0 0.2 2.9 0.8 2.4 6.1 0.0 0.1 0.0 7.3 1.3 GSTM1 "GST1, H-B, MU" ENSG00000134184 "Glutathione S-transferase mu 1" P09488 1 109687814-109709039 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 479.1;liver: 609.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Alveolar cells type 2: 6.8;Cardiomyocytes: 6.0;Club cells: 6.7;Hepatocytes: 5.5;Kupffer cells: 7.1" "Cancer enhanced" "Detected in all" "urothelial cancer: 63.1" "Region enriched" "Detected in all" 18 "cerebral cortex: 479.1" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 87.0;HeLa: 96.1;HHSteC: 78.6;hTEC/SVTERT24-B: 73.0;HUVEC TERT2: 62.4;MOLT-4: 115.4;U-266/84: 64.4" "Low region specificity" "Detected in all" "CAB022669, CAB047357, HPA048652, HPA055972, HPA055973" Approved Approved "Cytokinetic bridge,Cytosol" Yes NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" Cytosol "Cytokinetic bridge" "CAB022669: , CAB047357: , HPA048652: AB_2680478, HPA055972: AB_2682992, HPA055973: AB_2682993" "unprognostic (2.22e-2)" "unprognostic (5.35e-2)" "unprognostic (3.87e-3)" "unprognostic (3.20e-1)" "unprognostic (4.95e-2)" "unprognostic (1.03e-1)" "unprognostic (3.56e-2)" "unprognostic (1.81e-1)" "unprognostic (2.41e-1)" "unprognostic (6.55e-2)" "unprognostic (2.34e-1)" "unprognostic (3.45e-1)" "unprognostic (3.17e-2)" "unprognostic (2.12e-1)" "unprognostic (1.36e-1)" "unprognostic (2.18e-1)" "unprognostic (4.72e-3)" 55.5 155.7 26.1 17.4 26.4 9.7 56.9 24.9 479.1 61.5 26.9 39.1 27.9 38.1 69.6 152.3 45.8 29.4 30.5 25.9 25.8 37.3 609.6 28.2 1.8 25.5 26.3 178.4 66.8 48.7 33.5 8.7 26.1 47.0 22.4 10.2 43.8 128.6 69.3 73.5 47.3 64.3 25.0 63.6 59.5 57.0 26.6 33.5 27.7 0.0 17.9 127.0 135.2 25.3 0.3 0.6 0.3 1.3 0.0 0.0 0.5 0.0 0.3 0.2 0.4 1.0 7.0 26.9 0.1 41.6 0.0 1.3 0.1 0.6 0.7 0.1 0.4 87.0 96.1 1.7 78.6 0.0 0.7 0.1 0.1 73.0 0.3 48.1 62.4 50.1 0.0 56.8 2.5 0.0 115.4 0.7 54.6 0.1 0.0 0.4 0.6 11.1 9.0 0.1 5.3 0.7 0.0 0.3 0.5 2.6 1.1 44.5 0.2 35.5 2.0 0.9 0.1 45.1 64.4 3.7 30.7 1.1 2.0 2.2 26.1 32.2 28.8 39.1 31.0 30.8 31.4 28.5 77.8 32.5 33.1 32.6 2.0 30.1 17.4 41.1 38.9 28.5 26.1 26.4 24.9 479.1 25.9 25.8 25.5 26.3 26.1 25.0 26.6 25.3 0.3 9.6 6.8 0.0 0.2 1.8 0.6 2.0 0.0 0.1 2.7 1.9 6.0 2.8 6.7 0.0 0.0 0.0 0.8 0.4 0.0 1.2 0.0 0.9 1.9 0.8 0.0 0.0 0.0 0.0 0.0 1.7 0.0 1.5 2.5 0.0 5.0 5.5 0.1 0.0 0.0 0.3 0.0 7.1 2.2 0.4 3.7 0.5 0.0 0.0 0.7 2.4 0.0 0.0 0.0 0.6 0.1 2.2 0.0 0.1 1.9 0.0 5.1 0.0 0.0 0.3 1.4 0.5 0.4 0.0 1.6 0.0 0.8 0.0 0.2 1.8 GSTM4 ENSG00000168765 "Glutathione S-transferase mu 4" Q03013 1 109656099-109674836 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 149.5" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 382.8;Proximal tubular cells: 109.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "eosinophil: 351.7" "Lineage enriched" "Detected in all" 9 "granulocytes: 351.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048652, HPA055972, HPA055973" Approved Approved "Cytokinetic bridge,Cytosol" Yes NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" Cytosol "Cytokinetic bridge" "HPA048652: AB_2680478, HPA055972: AB_2682992, HPA055973: AB_2682993" "prognostic favorable (9.96e-5)" "unprognostic (1.96e-3)" "unprognostic (7.49e-2)" "unprognostic (9.92e-3)" "unprognostic (1.48e-1)" "unprognostic (1.08e-2)" "unprognostic (8.47e-2)" "unprognostic (3.48e-2)" "unprognostic (1.20e-1)" "unprognostic (4.76e-2)" "unprognostic (3.73e-1)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" "unprognostic (1.92e-2)" "unprognostic (2.20e-1)" "unprognostic (1.41e-1)" "unprognostic (2.47e-2)" 22.3 31.1 19.7 15.3 23.7 5.9 22.5 19.1 23.8 24.5 40.0 45.4 149.5 22.6 24.3 31.3 22.2 17.8 33.5 19.2 19.9 45.9 41.2 14.6 11.8 20.7 20.9 42.9 21.2 57.8 18.6 7.6 20.2 25.8 38.5 12.5 21.2 41.0 92.4 20.6 99.4 25.7 21.1 30.2 28.8 15.1 20.1 9.9 27.7 45.5 15.6 36.8 28.8 20.2 13.5 6.0 10.5 78.9 23.0 35.1 13.4 4.3 34.1 9.8 12.8 43.3 1.5 12.5 16.1 19.1 19.3 13.6 27.1 14.4 6.2 18.9 0.0 27.4 23.5 38.8 37.1 9.5 31.8 22.3 14.0 12.6 0.0 27.5 8.1 31.7 12.8 18.4 6.9 12.7 8.1 41.9 8.2 56.3 31.9 16.9 5.8 18.5 38.8 9.6 7.4 17.6 0.2 68.2 54.9 7.8 18.6 20.1 3.6 11.4 44.0 12.5 6.3 27.0 51.4 1.1 37.1 13.9 32.5 11.9 14.5 351.7 12.2 14.5 7.4 17.0 9.3 14.1 37.8 14.9 8.9 10.7 1.8 12.8 3.6 12.6 14.1 12.6 19.7 23.7 19.1 23.8 19.2 19.9 20.7 20.9 20.2 21.1 20.1 20.2 6.9 9.6 2.7 11.4 9.9 18.1 27.3 17.9 18.8 6.2 14.7 19.0 30.2 21.5 9.5 31.3 0.0 21.0 13.9 53.0 101.8 45.9 3.0 4.5 10.8 8.6 7.2 4.2 3.3 57.7 18.6 22.9 13.3 5.4 21.0 13.3 14.3 35.7 35.6 5.0 3.3 45.9 6.1 17.2 26.0 6.4 30.1 14.9 40.9 2.8 14.8 23.9 17.5 5.0 3.4 35.4 38.6 24.8 13.3 6.7 382.8 109.8 7.5 5.4 32.9 15.3 23.2 7.0 7.3 23.0 15.3 8.8 11.2 12.6 96.7 26.9 GSTM5 ENSG00000134201 "Glutathione S-transferase mu 5" P46439 1 109711780-109775428 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "breast: 929.9" "Group enriched" "Detected in many" 4 "Fibroblasts: 59.0;Leydig cells: 143.5;Muller glia cells: 213.3;Peritubular cells: 127.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "plasmacytoid DC: 3.9" "Lineage enriched" "Detected in single" 4 "dendritic cells: 3.9" "Group enriched" "Detected in some" 5 "fHDF/TERT166: 21.6;HHSteC: 10.3;HSkMC: 10.9" "HPA055972, HPA055973" Approved Uncertain "Cytokinetic bridge,Cytosol" Yes NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 5: Breast - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Cytosol "Cytokinetic bridge" "HPA055972: AB_2682992, HPA055973: AB_2682993" "unprognostic (1.46e-2)" "unprognostic (8.64e-3)" "unprognostic (5.58e-2)" "unprognostic (1.42e-1)" "unprognostic (5.34e-3)" "unprognostic (8.09e-2)" "unprognostic (9.64e-4)" "unprognostic (1.31e-2)" "unprognostic (1.44e-1)" "unprognostic (9.16e-2)" "unprognostic (3.31e-1)" "unprognostic (1.92e-2)" "unprognostic (1.42e-2)" "unprognostic (3.74e-2)" "unprognostic (4.39e-2)" "unprognostic (3.03e-3)" "unprognostic (1.40e-1)" 21.7 6.4 60.3 4.6 65.3 0.5 929.9 60.4 71.1 72.5 62.9 13.9 2.3 35.1 32.9 11.6 62.0 25.8 17.0 61.4 54.5 5.5 3.9 18.0 5.0 57.2 55.4 213.9 4.7 0.2 9.4 0.8 56.7 27.9 7.8 12.4 7.9 32.6 3.9 12.2 10.3 26.5 60.1 7.7 13.2 11.4 53.5 6.4 9.1 14.0 6.5 27.9 47.6 58.6 0.0 0.0 0.0 0.0 1.7 1.6 0.4 1.3 0.0 0.3 0.2 0.0 0.0 0.1 0.0 21.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.8 0.0 0.0 10.3 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.7 0.1 0.0 0.1 0.0 0.6 0.0 3.9 0.9 0.7 60.3 65.3 60.4 71.1 61.4 54.5 57.2 55.4 56.7 60.1 53.5 58.6 2.5 0.0 0.5 32.3 0.0 6.6 0.9 0.2 0.0 2.0 0.5 0.8 0.9 1.5 0.0 0.0 2.1 0.0 0.3 0.0 0.0 0.0 9.0 0.3 12.3 2.2 0.0 2.1 0.1 0.0 0.1 59.0 1.1 0.3 0.0 0.6 5.7 0.0 0.3 0.0 0.5 0.1 0.0 0.6 9.3 15.1 143.5 0.6 10.6 1.9 0.0 213.3 0.0 2.0 0.3 0.0 0.0 127.2 0.1 0.1 0.1 0.0 0.0 6.8 26.3 2.3 9.4 2.0 1.8 1.0 6.5 0.0 2.8 2.4 0.1 0.6 GTF2IRD1 "BEN, Cream1, GTF3, MusTRD1, RBAP2, WBSCR11, WBSCR12" ENSG00000006704 "GTF2I repeat domain containing 1" Q9UHL9 7 74453790-74602605 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 68.1" "Cell type enhanced" "Detected in many" "Astrocytes: 48.3;Inhibitory neurons: 42.1;Rod photoreceptor cells: 41.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044254 Approved Supported Nucleoplasm,Cytosol Yes No "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm Cytosol "HPA044254: AB_10964747" "unprognostic (8.92e-2)" "unprognostic (6.94e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (9.71e-5)" "unprognostic (2.24e-1)" "unprognostic (3.35e-2)" "unprognostic (2.71e-3)" "unprognostic (3.77e-2)" "unprognostic (1.84e-2)" "unprognostic (6.26e-2)" "unprognostic (4.89e-3)" "unprognostic (3.31e-1)" "unprognostic (2.53e-1)" "unprognostic (8.61e-2)" "unprognostic (1.08e-1)" "unprognostic (3.06e-2)" "unprognostic (2.25e-3)" 6.0 12.6 7.0 3.4 7.0 0.5 6.9 7.2 8.1 16.8 14.0 15.1 7.7 11.3 8.6 26.7 8.8 5.7 11.6 6.0 8.4 18.6 4.6 11.7 1.0 9.2 8.9 10.5 10.0 18.9 27.6 5.8 9.0 13.3 5.6 36.7 17.3 8.2 68.1 22.4 6.7 8.4 6.7 2.0 13.9 5.0 10.1 3.4 17.4 29.7 5.4 15.0 19.8 10.2 21.2 12.9 28.1 30.8 22.2 10.8 0.2 8.8 23.7 17.1 17.7 21.7 30.1 5.4 6.5 18.1 41.7 11.6 22.6 10.2 12.6 0.2 13.0 1.1 43.1 26.1 71.2 0.2 0.7 14.7 42.1 12.0 48.9 39.7 8.9 10.4 15.5 0.1 19.2 26.1 2.7 18.9 22.6 25.7 12.8 28.1 16.4 20.0 32.7 14.6 23.1 30.5 21.7 39.0 19.9 14.2 23.4 21.2 4.6 17.5 16.9 11.4 20.5 1.1 3.4 8.9 6.7 0.3 14.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 7.0 7.0 7.2 8.1 6.0 8.4 9.2 8.9 9.0 6.7 10.1 10.2 0.9 9.6 8.2 48.3 0.1 7.9 9.9 10.5 9.6 30.8 5.6 4.1 10.4 12.8 6.8 9.2 33.3 1.4 1.5 4.5 11.7 7.6 1.6 11.5 8.0 4.1 4.2 0.8 24.6 9.2 1.8 5.6 6.1 17.0 2.5 8.0 2.9 3.1 2.6 21.9 42.1 3.6 8.2 1.2 5.7 0.3 4.1 2.5 7.2 14.0 0.7 5.9 1.0 25.6 24.9 11.6 3.2 5.7 0.0 17.8 3.6 17.4 12.7 41.1 0.0 19.0 5.7 0.1 3.7 18.2 6.7 2.9 1.1 2.4 7.4 15.8 GTSE1 "B99, GTSE-1" ENSG00000075218 "G2 and S-phase expressed 1" Q9NYZ3 22 46296870-46330810 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.2;lymphoid tissue: 19.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 52.2;Extravillous trophoblasts: 31.2;Granulosa cells: 27.1;Spermatocytes: 73.6;Spermatogonia: 27.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA029457 Approved "Plasma membrane,Centrosome" Yes Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "Plasma membrane" "HPA029457: " "unprognostic (1.97e-1)" "unprognostic (3.07e-2)" "unprognostic (1.71e-3)" "unprognostic (2.59e-1)" "unprognostic (7.16e-2)" "unprognostic (2.40e-2)" "prognostic unfavorable (1.90e-10)" "prognostic unfavorable (4.66e-4)" "unprognostic (1.09e-1)" "unprognostic (8.37e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (3.49e-3)" "unprognostic (0.00e+0)" "unprognostic (6.52e-3)" "unprognostic (3.25e-1)" "unprognostic (1.14e-1)" "unprognostic (4.85e-2)" 0.6 0.6 0.2 5.1 0.2 11.2 0.5 0.5 0.3 0.7 0.2 2.4 4.1 0.8 0.0 3.6 0.2 0.5 0.3 0.2 0.3 0.3 0.4 0.6 9.2 0.4 0.3 0.2 0.2 0.1 0.1 2.6 0.4 0.2 2.6 0.1 0.7 0.1 0.1 2.5 2.9 1.2 0.1 2.4 1.9 7.2 0.5 19.6 0.2 0.2 8.7 1.0 1.2 0.4 59.5 27.6 53.2 42.2 1.1 3.0 25.5 50.3 23.5 71.7 58.8 29.3 21.9 55.7 13.0 19.4 32.8 30.3 48.0 12.7 45.7 33.7 52.0 37.4 38.9 22.8 0.1 67.5 43.8 0.6 1.0 30.9 15.6 7.5 31.2 39.7 29.0 67.8 43.4 33.1 60.9 33.0 37.2 24.2 30.7 59.6 59.7 36.3 11.7 10.7 27.5 37.5 48.1 30.7 21.5 23.8 26.2 25.8 25.1 40.6 75.8 33.4 53.7 38.6 19.7 56.3 25.8 32.2 60.5 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.5 0.3 0.0 0.4 0.3 0.2 0.2 0.2 0.5 0.3 0.2 0.3 0.4 0.3 0.4 0.1 0.5 0.4 1.1 0.0 0.0 0.7 7.0 2.8 1.1 2.1 0.6 0.7 2.8 3.4 1.6 0.0 0.5 0.0 0.0 19.2 6.8 7.6 0.0 0.9 5.6 2.1 4.7 3.9 1.2 52.2 0.3 0.2 31.2 5.1 16.8 4.3 0.0 27.1 6.4 1.2 19.9 0.0 0.5 9.4 2.0 7.5 4.0 3.9 0.3 4.7 0.0 0.0 0.1 0.4 0.0 0.5 0.1 0.8 0.2 0.7 19.1 1.8 0.5 0.5 0.2 0.3 6.6 2.6 5.4 73.6 27.8 11.7 2.6 1.5 5.0 1.2 13.8 1.6 GXYLT2 GLT8D4 ENSG00000172986 "Glucoside xylosyltransferase 2" A0PJZ3 3 72888046-72998138 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 47.9;Endometrial stromal cells: 45.4;Fibroblasts: 23.0;Late spermatids: 27.1;Oligodendrocytes: 61.3;Skeletal myocytes: 40.0;Theca cells: 22.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 22.3;JURKAT: 22.1;MOLT-4: 36.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA068429 Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Midbody ring" Yes No "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Cytokinetic bridge, Midbody ring" "HPA068429: AB_2685988" "unprognostic (9.43e-2)" "unprognostic (8.87e-3)" "unprognostic (1.90e-1)" "unprognostic (4.77e-2)" "unprognostic (3.33e-2)" "unprognostic (7.04e-2)" "unprognostic (4.79e-3)" "unprognostic (5.29e-2)" "unprognostic (5.25e-2)" "unprognostic (5.10e-2)" "unprognostic (2.00e-1)" "unprognostic (7.33e-2)" "prognostic unfavorable (1.46e-7)" "unprognostic (3.22e-3)" "unprognostic (4.70e-1)" "unprognostic (2.51e-1)" "prognostic unfavorable (2.42e-5)" 6.0 3.8 2.6 5.2 5.3 1.8 4.0 4.3 3.2 5.7 2.6 3.7 0.6 5.6 2.5 3.2 5.1 10.1 13.6 2.0 2.4 0.9 0.3 3.8 1.5 6.2 5.8 16.5 4.2 2.4 1.9 4.0 4.1 3.3 2.0 0.4 5.3 4.0 0.8 1.7 1.2 5.5 5.3 0.7 1.3 5.8 4.6 6.7 8.8 1.5 1.0 5.7 3.6 6.9 0.2 1.8 0.1 11.2 9.9 19.3 1.7 1.8 4.2 4.0 9.8 0.5 1.2 0.0 3.1 4.9 22.3 0.1 1.0 2.2 3.8 0.0 1.3 0.0 7.2 12.4 12.6 4.9 0.0 18.8 1.1 9.7 1.6 6.0 0.0 22.1 5.8 0.1 2.4 2.7 36.5 0.1 6.6 0.1 2.2 0.2 9.5 0.0 1.3 1.7 1.1 5.0 9.8 0.5 1.3 2.0 3.7 1.5 0.1 4.3 13.5 13.3 6.5 1.0 0.1 0.2 11.1 2.3 7.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.6 0.3 0.0 2.6 5.3 4.3 3.2 2.0 2.4 6.2 5.8 4.1 5.3 4.6 6.9 1.6 3.2 2.6 7.2 0.1 1.9 1.9 5.3 0.0 0.6 1.5 7.6 14.6 2.8 2.3 0.0 0.0 0.2 1.5 1.4 0.0 0.1 47.9 5.7 45.4 0.6 3.5 0.0 8.3 1.1 0.3 23.0 0.0 7.5 0.0 8.0 0.7 0.0 0.4 0.0 9.0 2.9 0.0 0.0 4.0 27.1 8.1 0.5 0.0 12.2 0.0 2.5 0.0 3.0 61.3 0.8 0.4 7.2 0.0 2.0 0.6 0.5 2.1 0.4 0.0 40.0 3.9 2.5 4.2 0.2 0.4 0.8 0.4 22.9 1.6 0.4 H1-0 "H1.0, H1F0, H1FV" ENSG00000189060 "H1.0 linker histone" P07305 22 37805093-37807436 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 660.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 51.4;Cytotrophoblasts: 42.9;Extravillous trophoblasts: 125.7;Hofbauer cells: 73.2;Syncytiotrophoblasts: 219.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 8.1;granulocytes: 17.1;monocytes: 11.7" "Cell line enhanced" "Detected in many" "OE19: 662.8;U-2 OS: 823.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000843 Supported Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus,Actin filaments" Yes No 120000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nuclear bodies" "Golgi apparatus, Actin filaments" "HPA000843: AB_1079062" "unprognostic (1.29e-2)" "unprognostic (1.68e-1)" "unprognostic (1.69e-2)" "unprognostic (1.27e-1)" "unprognostic (3.31e-3)" "unprognostic (1.19e-1)" "unprognostic (2.18e-1)" "unprognostic (3.85e-1)" "unprognostic (7.68e-2)" "unprognostic (1.86e-1)" "unprognostic (5.95e-3)" "unprognostic (4.86e-3)" "prognostic favorable (7.68e-7)" "unprognostic (3.40e-1)" "unprognostic (1.47e-1)" "unprognostic (1.37e-3)" "unprognostic (1.73e-1)" 89.8 53.5 56.6 36.7 55.4 660.5 121.4 72.5 64.1 218.3 42.5 146.2 129.9 168.2 43.5 230.6 119.7 56.3 86.5 55.4 67.1 292.8 179.3 72.4 24.4 58.4 54.2 120.7 125.9 93.2 58.2 80.0 57.7 151.7 120.0 39.9 155.3 40.2 216.2 228.6 137.1 97.7 52.6 36.7 131.2 42.4 58.3 136.2 93.9 93.5 46.6 85.6 194.9 55.8 159.6 67.9 206.0 91.8 53.4 48.4 291.6 126.9 262.3 362.6 512.6 278.1 247.3 0.2 31.1 106.3 84.1 303.8 0.0 87.2 256.0 0.9 15.3 268.2 25.3 187.4 185.8 0.1 0.7 45.4 152.4 182.3 203.2 4.0 97.8 60.4 0.1 0.5 28.5 263.3 45.4 26.5 80.2 662.8 329.9 74.6 122.6 56.1 58.0 42.7 47.3 263.9 349.9 235.4 473.9 91.8 184.2 167.1 65.4 27.4 823.3 122.7 25.9 0.7 18.5 1.2 33.5 95.9 80.3 17.1 9.9 15.7 0.1 11.7 0.1 0.0 1.0 0.2 8.1 0.1 2.8 0.4 5.4 0.1 10.3 7.4 0.2 6.9 56.6 55.4 72.5 64.1 55.4 67.1 58.4 54.2 57.7 52.6 58.3 55.8 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.4 0.0 0.0 0.0 0.0 42.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 125.7 25.2 0.0 0.0 0.0 0.0 0.0 0.0 73.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 219.7 0.0 0.0 0.0 0.0 H2AX H2AFX ENSG00000188486 "H2A.X variant histone" P16104 11 119093854-119095467 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair, Host-virus interaction, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 43.7;Cytotrophoblasts: 83.2;dendritic cells: 34.0;Extravillous trophoblasts: 106.6;Hofbauer cells: 45.8;Syncytiotrophoblasts: 64.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012264, HPA041189, HPA051647" Supported Supported "Nucleoplasm,Nuclear speckles" Yes Yes "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Nuclear speckles" "CAB012264: AB_297215, HPA041189: AB_2677357, HPA051647: AB_2681563" "unprognostic (1.44e-1)" "unprognostic (1.96e-1)" "unprognostic (6.46e-2)" "unprognostic (6.41e-2)" "unprognostic (3.07e-1)" "unprognostic (3.25e-1)" "prognostic unfavorable (1.51e-4)" "unprognostic (2.32e-3)" "unprognostic (1.93e-1)" "unprognostic (3.07e-3)" "unprognostic (6.78e-2)" "unprognostic (9.31e-2)" "prognostic unfavorable (5.47e-9)" "unprognostic (1.21e-3)" "unprognostic (1.20e-1)" "unprognostic (1.20e-1)" "unprognostic (1.99e-2)" 13.2 20.7 35.2 12.6 37.8 24.9 8.0 39.0 42.2 13.3 20.6 18.6 13.3 14.0 2.1 43.6 13.1 3.1 13.4 33.7 32.3 17.0 13.9 14.3 16.0 43.9 38.9 18.7 11.6 3.4 24.3 11.0 37.8 15.7 4.3 6.6 11.4 4.7 12.4 18.1 18.8 3.5 38.0 24.0 16.1 15.4 37.8 30.5 10.4 3.6 12.0 11.8 15.7 51.8 132.1 77.9 120.3 72.3 10.9 7.9 126.4 146.0 44.0 80.3 70.4 124.0 55.1 89.7 85.9 34.0 60.5 134.0 57.5 41.7 21.5 133.4 161.0 182.2 20.7 129.8 11.4 90.5 108.9 6.7 9.0 34.2 21.0 13.1 40.7 115.4 149.9 143.1 38.9 335.6 207.8 269.9 87.5 60.0 162.6 200.7 141.6 42.7 37.5 56.3 127.6 152.0 116.0 66.6 20.6 20.6 99.8 68.2 50.9 77.7 204.2 63.8 110.2 38.7 40.8 92.3 17.9 145.2 155.0 3.8 1.3 4.2 1.6 0.6 0.8 0.9 1.7 1.7 1.8 0.8 1.1 1.0 0.6 2.2 0.8 0.8 1.6 1.2 35.2 37.8 39.0 42.2 33.7 32.3 43.9 38.9 37.8 38.0 37.8 51.8 43.7 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.0 0.0 0.0 83.2 34.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 106.6 9.4 0.0 0.0 0.0 0.0 0.0 0.0 45.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 64.2 7.2 0.0 0.0 0.0 HAUS3 "C4orf15, dgt3, IT1, MGC4701" ENSG00000214367 "HAUS augmin like complex subunit 3" Q68CZ6 4 2078998-2242276 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040649, HPA048190" Approved Uncertain "Microtubules,Cytokinetic bridge,Mitotic spindle,Mitochondria" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA040649: AB_2677060, HPA048190: AB_2680308" "unprognostic (4.22e-2)" "unprognostic (1.50e-1)" "unprognostic (6.30e-2)" "unprognostic (2.87e-1)" "unprognostic (2.26e-1)" "unprognostic (2.57e-3)" "unprognostic (7.63e-3)" "unprognostic (2.14e-1)" "unprognostic (1.19e-1)" "unprognostic (1.19e-1)" "unprognostic (1.17e-1)" "unprognostic (3.81e-3)" "unprognostic (2.79e-2)" "unprognostic (2.15e-2)" "unprognostic (2.79e-1)" "unprognostic (4.40e-2)" "prognostic favorable (4.78e-5)" 9.6 8.6 3.5 7.5 3.5 27.5 8.9 9.0 4.6 8.1 1.9 8.3 6.5 7.3 4.9 8.0 7.2 4.2 5.8 3.4 3.2 6.2 7.4 9.0 10.2 3.4 3.4 7.3 10.5 4.0 5.6 6.5 3.3 8.5 5.3 5.8 8.5 4.5 7.4 8.9 9.2 4.7 2.3 12.0 9.0 10.7 3.4 8.6 7.4 4.6 8.3 7.1 7.7 4.3 9.8 4.7 14.2 13.0 5.5 8.5 12.8 14.3 6.0 12.7 10.6 9.5 12.5 18.9 6.5 5.7 14.3 9.3 11.9 7.2 15.9 6.8 6.9 12.5 13.1 7.0 4.5 11.6 11.2 4.3 10.2 11.0 5.8 6.6 10.3 8.8 22.0 21.2 12.5 5.4 19.6 19.5 11.2 8.5 12.3 13.9 12.4 10.4 6.3 6.7 18.4 10.0 10.1 7.6 8.4 10.5 15.7 7.8 8.5 18.1 7.8 11.1 17.0 11.2 10.6 16.9 8.8 16.8 12.0 9.6 4.2 12.2 7.9 5.8 10.1 5.5 8.2 8.9 3.8 9.1 9.5 8.9 4.7 10.7 6.9 6.8 12.0 6.6 3.5 3.5 9.0 4.6 3.4 3.2 3.4 3.4 3.3 2.3 3.4 4.3 15.5 3.2 4.8 0.0 15.8 12.6 5.0 6.4 15.4 11.9 9.3 8.8 5.8 7.2 10.3 3.7 12.5 7.3 24.0 3.9 1.9 7.4 11.8 8.9 11.8 9.4 7.2 23.1 0.0 5.7 11.7 9.6 4.6 8.3 13.3 12.1 6.8 3.7 7.2 25.2 0.0 6.4 12.2 5.4 9.3 6.4 9.9 10.4 12.4 0.0 7.9 6.5 16.5 0.0 0.0 5.3 1.8 8.6 22.5 5.1 5.8 2.6 5.4 12.5 0.0 12.3 17.7 34.4 25.3 10.5 7.7 5.1 26.5 10.1 5.8 3.0 HEATR3 FLJ20718 ENSG00000155393 "HEAT repeat containing 3" Q7Z4Q2 16 50065970-50107272 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041990, HPA058579" Uncertain Enhanced Nucleoplasm,Cytosol Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm Cytosol "HPA041990: AB_10793940, HPA058579: AB_2683762" "unprognostic (7.36e-3)" "unprognostic (2.72e-1)" "unprognostic (2.01e-3)" "unprognostic (1.97e-1)" "unprognostic (1.20e-1)" "unprognostic (4.80e-3)" "prognostic unfavorable (4.11e-5)" "unprognostic (7.68e-2)" "unprognostic (5.11e-2)" "unprognostic (8.79e-2)" "unprognostic (4.96e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (5.16e-6)" "unprognostic (2.26e-1)" "unprognostic (1.76e-1)" "unprognostic (1.86e-1)" "unprognostic (3.17e-2)" 7.1 8.2 3.8 9.0 3.7 5.6 5.3 4.6 4.2 5.1 4.3 7.0 4.9 5.0 4.5 8.0 4.8 4.2 6.4 3.7 3.6 6.7 10.2 6.3 6.6 4.2 3.2 3.3 8.0 4.8 6.5 5.8 3.4 4.9 6.3 4.8 6.0 3.4 12.0 6.3 7.0 5.3 3.2 12.6 6.6 5.8 3.8 4.6 3.7 6.2 6.2 5.1 5.1 3.9 13.0 12.8 11.8 18.6 7.0 9.6 12.6 15.5 10.1 15.0 6.0 15.9 9.4 24.4 10.9 14.7 5.6 15.1 14.1 11.3 17.2 6.1 15.4 12.1 9.0 20.4 10.2 21.1 23.5 7.5 7.8 10.4 6.2 6.6 12.2 12.6 15.5 3.9 14.9 7.8 16.2 26.4 13.8 15.5 13.1 17.6 15.8 19.8 8.4 10.4 15.1 8.0 14.8 18.9 10.0 8.8 8.5 15.4 16.1 12.0 8.0 9.1 11.8 9.8 8.0 21.3 11.7 20.9 12.0 0.5 2.4 0.5 0.9 2.8 1.0 0.6 0.5 1.0 1.7 0.8 0.8 0.9 0.5 0.7 2.6 1.5 0.9 1.0 3.8 3.7 4.6 4.2 3.7 3.6 4.2 3.2 3.4 3.2 3.8 3.9 4.2 3.2 5.8 7.8 4.6 3.2 1.4 1.5 3.4 7.8 3.1 2.0 6.0 2.8 1.8 1.8 16.7 3.5 7.1 3.3 7.9 2.4 10.7 3.7 6.8 4.6 3.5 3.8 21.2 3.1 3.6 4.7 7.7 3.8 1.3 6.5 1.8 9.6 9.4 1.7 16.7 3.2 4.1 22.2 4.7 18.3 3.4 13.9 1.8 7.5 13.3 2.4 3.1 20.1 12.8 2.9 2.5 2.2 7.2 1.9 4.7 4.1 2.8 8.1 0.0 2.5 4.2 5.3 4.8 7.6 1.7 1.0 5.8 6.7 5.8 1.5 HEPACAM2 FLJ38683 ENSG00000188175 "HEPACAM family member 2" A8MVW5 7 93188534-93226469 "Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "intestine: 96.2" "Group enriched" "Detected in some" 11 "Enteroendocrine cells: 218.2;Intestinal goblet cells: 387.5;Ionocytes: 349.9;Paneth cells: 318.1" "Group enriched" "Detected in many" 5 "colorectal cancer: 8.4;pancreatic cancer: 10.7;renal cancer: 10.6;stomach cancer: 5.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 36 "SCLC-21H: 172.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA012381 Supported "Nucleoplasm,Vesicles,Mitotic spindle" Yes NA 210000 "Cluster 9: Intestine - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 27: Mucus-secreting cells - Mucin production" "Vesicles, Mitotic spindle" Nucleoplasm "HPA012381: AB_1853037" "unprognostic (2.01e-3)" "unprognostic (6.05e-2)" "prognostic favorable (9.73e-5)" "unprognostic (1.33e-2)" "unprognostic (7.27e-2)" "unprognostic (2.24e-2)" "unprognostic (4.48e-2)" "unprognostic (8.40e-3)" "unprognostic (7.61e-2)" "unprognostic (8.68e-2)" "unprognostic (5.37e-3)" "unprognostic (4.93e-2)" "unprognostic (3.64e-3)" "unprognostic (2.06e-1)" "unprognostic (4.73e-2)" "unprognostic (3.82e-1)" "unprognostic (6.34e-2)" 0.1 0.1 0.0 2.3 0.0 2.5 8.9 0.0 0.1 0.0 0.0 64.3 30.1 0.0 0.5 0.1 0.0 0.2 0.1 0.0 0.0 15.2 0.0 0.1 0.0 0.1 0.1 0.0 4.3 0.4 7.3 0.2 0.0 0.8 96.2 0.0 2.6 1.4 0.0 0.0 48.0 1.5 0.1 0.1 10.1 3.2 0.0 0.1 0.0 0.0 1.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.5 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 172.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.7 0.4 0.3 1.1 0.7 0.0 0.0 15.1 6.6 0.2 0.0 0.9 5.5 0.0 0.0 0.0 17.2 9.8 0.1 2.5 0.0 0.0 0.1 218.2 18.7 0.5 0.0 0.0 0.1 27.5 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.6 387.5 349.9 0.0 0.0 2.4 0.0 0.0 7.2 1.0 0.0 0.0 0.0 0.0 2.2 0.0 318.1 0.0 0.1 0.9 11.5 0.0 0.3 0.0 0.0 0.0 0.1 5.6 1.2 0.0 0.1 0.1 0.1 0.0 19.7 0.3 HEPN1 ENSG00000221932 "Hepatocellular carcinoma, down-regulated 1" Q6WQI6 11 124919244-124920677 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "adipose tissue: 11.4;brain: 37.3;liver: 20.9" "Group enriched" "Detected in some" 23 "Astrocytes: 94.3;Muller glia cells: 29.1;Oligodendrocyte precursor cells: 49.3;Oligodendrocytes: 114.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 287 "Hep G2: 55.5" "HPA043768, HPA063054" Uncertain Approved "Golgi apparatus" Yes NA "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Golgi apparatus" "HPA043768: AB_2678662, HPA063054: AB_2684932" 11.4 0.2 6.1 0.1 23.1 0.0 8.3 0.3 9.4 0.4 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.0 0.6 5.0 6.1 0.2 20.9 0.1 0.1 37.3 10.3 0.1 0.2 0.0 2.4 0.0 13.5 0.8 0.0 2.2 0.4 0.0 0.2 0.3 0.7 0.0 5.1 0.1 0.5 0.5 19.0 0.0 0.2 0.0 0.0 0.2 0.5 17.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 23.1 0.3 9.4 5.0 6.1 37.3 10.3 13.5 5.1 19.0 17.9 0.2 0.0 0.0 94.3 0.0 0.0 0.1 0.0 0.0 0.8 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 3.1 0.0 0.0 1.1 0.0 0.0 0.0 0.6 0.5 0.6 0.0 0.0 1.9 0.0 29.1 0.0 49.3 114.6 0.0 0.0 1.2 0.0 0.1 0.0 2.2 0.0 1.9 0.0 0.1 0.1 1.8 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 HIGD1B "CLST11240, CLST11240-15" ENSG00000131097 "HIG1 hypoxia inducible domain family member 1B" Q9P298 17 44846353-44850476 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 114.6;choroid plexus: 65.0;placenta: 105.2" "Group enriched" "Detected in some" 5 "Sertoli cells: 762.6;Smooth muscle cells: 209.3" "Cancer enhanced" "Detected in all" "glioma: 9.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in some" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA079501 Uncertain "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA079501: " "unprognostic (6.85e-2)" "unprognostic (9.41e-2)" "unprognostic (3.80e-3)" "unprognostic (2.07e-1)" "unprognostic (8.46e-2)" "unprognostic (2.37e-2)" "unprognostic (4.98e-3)" "unprognostic (3.61e-1)" "unprognostic (1.18e-2)" "unprognostic (3.98e-1)" "unprognostic (6.19e-2)" "unprognostic (3.56e-1)" "unprognostic (1.61e-3)" "unprognostic (5.23e-3)" "unprognostic (8.72e-2)" "unprognostic (1.79e-2)" "unprognostic (1.52e-2)" 11.7 0.5 71.0 0.7 71.0 0.5 8.8 70.3 114.6 8.3 65.0 3.7 2.1 9.9 11.6 5.0 5.3 11.3 46.4 68.8 71.4 11.5 0.6 38.6 2.6 71.4 70.9 2.9 3.1 8.0 1.4 105.2 72.4 9.5 1.1 2.3 1.4 6.4 14.5 2.0 4.3 11.3 68.9 0.1 3.7 1.5 73.0 1.8 5.0 30.8 1.4 4.3 4.4 69.1 0.2 0.6 0.0 0.7 0.0 0.0 0.6 0.6 0.0 0.0 0.0 0.3 0.2 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.7 0.1 0.8 0.5 0.0 0.9 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.7 0.5 0.0 0.3 0.7 0.7 0.4 0.3 0.3 0.8 0.4 1.0 0.0 0.5 0.7 0.3 0.2 0.0 0.1 0.0 0.3 0.3 0.0 0.6 0.2 0.4 0.5 0.4 1.2 0.6 0.5 1.1 0.7 1.7 0.6 0.2 1.2 1.0 0.4 0.2 0.7 0.9 1.2 0.3 0.9 0.7 0.0 0.7 0.1 0.3 0.8 0.5 71.0 71.0 70.3 114.6 68.8 71.4 71.4 70.9 72.4 68.9 73.0 69.1 88.9 0.0 0.5 0.0 0.3 3.4 0.6 0.3 0.0 0.5 1.2 2.8 11.0 0.0 1.3 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.2 0.2 0.7 70.2 0.0 0.0 0.7 0.0 0.2 4.4 0.0 0.3 0.0 0.0 0.7 0.1 0.8 1.7 0.6 0.0 0.0 0.0 3.9 0.6 0.3 1.6 0.0 2.8 0.0 1.0 0.0 0.5 0.5 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.9 762.6 9.5 209.3 0.0 0.3 0.7 2.4 0.3 0.8 32.3 0.0 0.7 HJURP "DKFZp762E1312, FAKTS, hFLEG1, URLC9" ENSG00000123485 "Holliday junction recognition protein" Q8NCD3 2 233833416-233854566 "Predicted intracellular proteins" "Cell cycle" "Chaperone, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.4;lymphoid tissue: 30.4" "Cell type enhanced" "Detected in many" "Early spermatids: 17.4;Erythroid cells: 38.3;Extravillous trophoblasts: 16.1;Granulosa cells: 14.8;Spermatocytes: 37.5;Spermatogonia: 16.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA008436, HPA027261" Uncertain Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitochondria" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli, Nucleoli rim" Mitochondria "HPA008436: AB_1850757, HPA027261: AB_2672184" "unprognostic (5.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.87e-1)" "unprognostic (1.44e-3)" "unprognostic (3.62e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (3.37e-5)" "prognostic unfavorable (2.46e-4)" "prognostic unfavorable (6.49e-4)" "unprognostic (9.48e-2)" "prognostic unfavorable (7.72e-5)" "unprognostic (7.60e-2)" "unprognostic (0.00e+0)" "unprognostic (7.42e-2)" "unprognostic (5.58e-2)" "unprognostic (1.89e-2)" "unprognostic (5.74e-2)" 0.6 0.6 0.0 5.5 0.1 47.4 1.1 0.1 0.2 0.8 0.1 3.9 4.1 0.9 0.2 5.6 0.3 0.5 0.3 0.1 0.1 0.4 0.8 1.4 12.6 0.1 0.3 0.2 0.2 0.1 0.1 3.0 0.1 0.4 5.2 0.1 1.0 0.1 0.2 3.6 3.8 1.9 0.0 4.1 2.4 11.1 0.3 30.4 0.3 0.0 12.0 1.4 2.0 0.2 54.5 73.6 68.4 32.7 2.6 5.4 42.8 79.5 37.9 55.2 59.9 51.3 57.6 17.1 9.0 31.4 98.0 61.7 54.9 40.9 72.6 40.0 21.6 65.5 61.4 50.9 0.3 54.1 43.2 1.8 1.5 45.1 30.9 15.7 35.5 51.3 56.6 40.8 103.0 55.3 76.4 59.7 58.9 42.2 49.1 58.4 103.0 30.3 28.6 32.3 39.4 24.7 45.8 34.2 31.7 31.0 25.7 42.1 26.0 59.6 64.6 44.3 87.2 38.6 32.7 67.9 35.7 39.3 151.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.4 0.0 1.2 0.4 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.3 0.1 0.0 0.3 0.2 0.2 0.0 0.5 0.0 2.9 1.3 0.5 1.9 0.0 0.0 0.7 0.5 1.2 0.0 2.1 0.0 0.0 8.2 0.5 5.6 0.0 0.2 17.4 0.3 1.3 1.1 0.0 38.3 0.0 0.0 16.1 2.0 5.1 1.3 0.0 14.8 2.2 0.3 7.1 0.0 0.0 3.5 0.0 3.0 2.9 9.0 0.6 3.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.0 11.4 1.0 0.5 0.1 0.1 0.0 0.0 0.1 1.9 37.5 16.3 8.9 0.9 1.5 2.3 0.3 7.6 0.9 HLF MGC33822 ENSG00000108924 "HLF transcription factor, PAR bZIP family member" Q16534 17 55264960-55325187 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 122.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 120.7;Excitatory neurons: 77.5;Hepatocytes: 156.8;Horizontal cells: 92.5;Microglial cells: 74.0" "Cancer enhanced" "Detected in many" "liver cancer: 13.6" "Region enhanced" "Detected in many" "cerebral cortex: 53.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "Hep G2: 163.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068156, HPA071210" Enhanced Nucleoplasm Yes NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA068156: AB_2685963, HPA071210: AB_2686361" "unprognostic (1.24e-1)" "unprognostic (1.19e-3)" "unprognostic (1.27e-1)" "unprognostic (1.35e-1)" "unprognostic (3.30e-1)" "prognostic favorable (1.88e-4)" "unprognostic (5.30e-3)" "prognostic favorable (2.71e-7)" "unprognostic (1.42e-1)" "unprognostic (3.44e-2)" "unprognostic (1.24e-3)" "unprognostic (2.19e-1)" "prognostic favorable (3.55e-6)" "unprognostic (8.47e-2)" "unprognostic (1.64e-1)" "unprognostic (6.85e-2)" "unprognostic (1.60e-2)" 15.1 21.5 9.8 1.9 23.1 0.4 15.4 0.0 53.3 14.4 0.0 18.0 1.4 14.4 11.0 26.3 12.2 7.8 24.1 17.6 0.0 12.7 122.4 13.4 2.2 0.0 0.6 50.0 2.9 4.0 9.9 1.0 0.0 13.2 3.4 43.2 24.1 12.4 7.7 16.7 4.3 12.3 0.0 8.2 6.1 4.1 3.9 3.4 34.3 9.9 7.7 12.3 7.8 17.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.9 0.5 0.0 0.0 0.0 0.4 0.2 0.0 27.3 0.7 0.0 0.1 163.0 0.1 0.9 0.2 0.1 0.7 0.0 0.1 0.3 0.0 1.4 0.0 0.6 0.0 0.6 1.1 0.0 0.1 0.0 2.4 0.0 0.4 0.4 13.0 0.1 11.1 0.6 0.0 7.2 0.2 0.0 0.2 0.0 0.1 0.8 0.2 0.6 0.5 5.1 4.9 0.0 0.3 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 9.8 23.1 0.0 53.3 17.6 0.0 0.0 0.6 0.0 0.0 3.9 17.2 13.8 3.2 42.8 22.2 0.4 22.3 4.4 1.4 56.9 120.7 5.9 16.4 38.6 12.8 6.3 7.3 10.4 0.1 0.5 0.0 11.7 1.9 1.3 0.1 6.2 19.7 3.0 0.8 77.5 0.9 0.0 17.6 0.0 0.6 0.0 0.5 6.1 156.8 0.1 92.5 36.6 0.6 0.0 3.5 4.0 4.7 28.3 0.7 10.6 74.0 0.1 60.7 0.0 24.6 6.9 0.4 0.0 39.1 1.5 1.3 2.8 23.3 1.0 15.0 13.1 4.5 7.4 0.4 5.0 33.7 27.6 1.2 3.8 0.5 0.4 0.4 HMBOX1 "FLJ21616, HNF1LA, HOT1, PBHNF" ENSG00000147421 "Homeobox containing 1" Q6NT76 8 28890395-29064764 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 20.0" "Cell type enhanced" "Detected in all" "Astrocytes: 125.7;Oligodendrocyte precursor cells: 118.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055855, HPA058586, CAB070418" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 14: Monocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "Nuclear bodies, Cytosol" "CAB070418: AB_11154826, HPA055855: AB_2682945, HPA058586: AB_2683764" "unprognostic (2.68e-3)" "unprognostic (2.30e-3)" "unprognostic (4.52e-2)" "unprognostic (1.41e-1)" "unprognostic (1.85e-1)" "unprognostic (1.03e-3)" "unprognostic (1.20e-1)" "unprognostic (2.75e-3)" "unprognostic (1.49e-1)" "unprognostic (4.25e-2)" "unprognostic (1.89e-2)" "unprognostic (1.65e-1)" "unprognostic (1.51e-1)" "unprognostic (3.84e-2)" "unprognostic (2.81e-1)" "unprognostic (1.02e-1)" "unprognostic (1.47e-1)" 4.6 6.7 7.6 5.1 11.9 10.8 4.2 10.6 5.7 3.7 1.7 3.8 3.1 4.4 3.0 3.2 3.7 4.2 4.5 5.3 17.9 4.3 4.2 4.6 5.3 15.0 20.0 6.1 3.3 5.0 1.8 6.8 15.6 2.9 3.9 6.2 3.1 2.5 2.8 4.4 4.3 5.2 10.4 5.7 4.3 7.6 11.6 4.9 6.2 3.7 5.9 3.8 2.4 12.9 6.2 6.8 7.1 8.2 6.5 6.7 6.0 2.6 3.5 4.0 4.3 3.1 3.9 15.1 6.3 4.5 6.0 5.3 14.4 5.3 5.6 5.5 2.4 15.6 13.8 4.2 5.3 5.4 10.2 3.3 7.5 5.3 10.1 4.9 9.1 9.0 22.7 14.4 5.7 3.8 9.9 2.7 5.0 6.6 1.6 8.1 7.1 3.4 2.8 11.5 3.0 9.2 5.1 3.9 5.4 5.9 3.9 4.8 13.0 3.6 16.8 3.9 3.8 4.4 4.8 5.9 4.6 6.5 5.4 3.2 2.4 1.1 1.9 2.6 2.7 3.4 1.9 1.8 2.5 2.6 2.4 2.4 1.4 1.2 4.7 1.9 0.8 1.4 7.6 11.9 10.6 5.7 5.3 17.9 15.0 20.0 15.6 10.4 11.6 12.9 25.5 16.0 18.1 125.7 30.3 16.7 15.8 18.1 15.9 24.4 15.3 10.5 23.6 20.0 14.0 29.5 39.6 12.9 18.7 16.2 15.6 8.3 93.0 15.0 21.2 34.2 17.4 19.6 90.1 14.4 14.1 19.2 11.2 29.4 17.1 36.7 68.6 13.7 10.3 30.3 109.8 12.9 22.4 19.8 36.4 31.5 35.8 20.1 16.0 91.8 21.4 28.3 26.8 118.1 111.8 14.1 11.3 31.6 14.4 21.0 20.4 8.8 14.3 31.6 19.7 34.6 17.3 43.6 15.2 10.1 19.7 19.2 22.8 19.5 14.7 22.6 HMMR "CD168, RHAMM" ENSG00000072571 "Hyaluronan mediated motility receptor" O75330 5 163460203-163491941 "CD markers, FDA approved drug targets, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.6;lymphoid tissue: 27.3;testis: 27.5" "Cell type enhanced" "Detected in many" "Early spermatids: 86.2;Erythroid cells: 133.3;Extravillous trophoblasts: 55.1;Late spermatids: 60.9;Spermatocytes: 100.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB002433, HPA040025, HPA043926, HPA061524" Enhanced Enhanced Microtubules,Centrosome,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules "Centrosome, Cytosol" "CAB002433: AB_564080, HPA040025: AB_2676805, HPA043926: , HPA061524: AB_2684551" "unprognostic (3.53e-3)" "unprognostic (1.01e-1)" "unprognostic (3.38e-3)" "unprognostic (8.88e-3)" "unprognostic (2.12e-1)" "prognostic unfavorable (5.52e-4)" "prognostic unfavorable (1.93e-7)" "prognostic unfavorable (1.09e-4)" "unprognostic (5.68e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (3.71e-5)" "unprognostic (1.02e-1)" "unprognostic (0.00e+0)" "unprognostic (1.65e-2)" "unprognostic (4.98e-2)" "unprognostic (2.39e-1)" "unprognostic (1.77e-2)" 0.8 0.7 0.2 10.1 0.3 20.6 2.1 0.3 0.4 1.1 0.1 6.6 7.4 0.8 0.2 4.0 0.5 0.9 0.8 0.2 0.2 0.7 1.7 0.9 18.1 0.5 0.3 0.2 0.3 0.9 0.2 6.2 0.4 0.5 8.8 0.8 0.8 0.2 1.2 4.2 6.5 2.9 0.3 2.9 3.6 27.5 0.7 27.3 0.7 0.4 17.7 2.2 1.4 0.5 77.0 47.2 94.5 50.8 5.0 9.0 70.3 71.4 34.9 88.0 78.9 96.8 145.1 127.5 66.0 22.2 118.5 86.3 112.4 69.0 148.6 116.1 34.4 76.7 32.3 48.4 1.4 68.7 67.3 2.4 4.1 82.8 64.0 14.7 50.6 85.7 73.2 101.0 93.2 28.5 72.3 38.8 81.9 51.2 51.6 78.0 126.3 63.9 34.8 20.4 78.8 43.8 106.3 32.8 38.6 45.1 97.3 54.5 32.9 63.2 52.4 50.6 97.2 53.7 96.3 102.4 41.4 104.2 61.1 0.2 0.2 0.0 0.1 0.1 0.3 0.3 0.3 0.1 0.2 0.2 0.1 0.2 0.1 0.5 0.0 0.6 1.5 0.2 0.2 0.3 0.3 0.4 0.2 0.2 0.5 0.3 0.4 0.3 0.7 0.5 0.4 0.0 1.1 1.3 6.0 2.5 1.8 4.5 2.8 0.6 3.2 3.7 2.5 4.3 3.2 0.0 0.0 37.3 2.3 5.3 0.0 0.8 86.2 3.8 3.1 3.1 1.2 133.3 0.6 0.2 55.1 4.6 11.7 5.7 0.0 21.6 5.3 3.8 22.2 0.0 0.4 7.8 6.1 8.8 2.7 60.9 2.1 7.6 0.0 0.0 2.3 0.1 1.0 0.5 1.2 0.2 0.3 0.7 22.9 1.5 1.3 2.6 2.8 1.0 6.6 0.6 3.8 100.9 23.3 14.1 1.4 4.5 5.2 1.6 15.6 3.0 HMX3 NKX5-1 ENSG00000188620 "H6 family homeobox 3" A6NHT5 10 123135970-123139423 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "brain: 6.9" "Cell type enriched" "Detected in single" 10 "Cardiomyocytes: 1.0" "Cancer enhanced" "Detected in single" "stomach cancer: 0.5" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HAP1: 8.1;HEL: 6.1;HeLa: 7.0;K-562: 17.9;NB-4: 13.4;SiHa: 7.0;THP-1: 5.7" "Region enriched" "Detected in single" 4 "hypothalamus: 1.1" "Group enriched" "Detected in some" 5 "basal ganglia: 1.4;hypothalamus: 4.8" HPA069659 Approved "Nucleoplasm,Centriolar satellite" Yes No "Cluster 17: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "Centriolar satellite" "HPA069659: AB_2686165" "unprognostic (1.79e-1)" "unprognostic (9.65e-2)" "unprognostic (6.07e-2)" 0.9 0.1 0.4 0.1 0.1 0.1 0.0 0.3 0.1 0.0 0.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.5 0.1 0.0 0.0 0.1 1.3 6.9 0.0 0.1 0.0 0.2 0.0 2.4 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.1 0.2 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.0 8.1 0.0 0.0 0.7 0.4 6.1 7.0 0.2 0.1 0.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 2.9 17.9 0.1 0.0 0.0 0.0 13.4 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.4 0.2 0.0 7.0 0.0 0.1 0.0 0.0 5.7 0.1 0.0 0.8 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.4 1.6 0.3 0.4 0.2 0.2 0.2 0.3 0.2 0.2 0.1 0.5 0.2 0.3 0.9 0.4 0.2 0.4 0.2 0.1 0.4 0.1 0.3 0.1 0.1 6.5 1.3 6.9 2.4 0.1 3.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HNF4G NR2A2 ENSG00000164749 "Hepatocyte nuclear factor 4 gamma" Q14541 8 75407914-75566834 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 114.6" "Cell type enhanced" "Detected in many" "Astrocytes: 39.8;Distal enterocytes: 51.0;Intestinal goblet cells: 32.3;Paneth cells: 54.3;Proximal enterocytes: 165.3;Undifferentiated cells: 36.9" "Group enriched" "Detected in many" 5 "colorectal cancer: 8.5;liver cancer: 2.8;pancreatic cancer: 4.0;renal cancer: 4.6;stomach cancer: 10.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.3;CAPAN-2: 16.1;Karpas-707: 4.5;OE19: 10.0;PC-3: 4.8;THP-1: 5.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005438, HPA010610" Enhanced Enhanced "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA005438: AB_1850822, HPA010610: AB_2668318" "unprognostic (2.09e-1)" "unprognostic (2.90e-1)" "unprognostic (1.77e-2)" "unprognostic (9.44e-2)" "unprognostic (5.60e-2)" "unprognostic (4.65e-2)" "unprognostic (5.26e-2)" "unprognostic (1.27e-2)" "unprognostic (3.92e-1)" "unprognostic (8.09e-2)" "unprognostic (3.68e-2)" "unprognostic (1.83e-2)" "unprognostic (6.93e-3)" "unprognostic (1.67e-2)" "unprognostic (2.11e-1)" "unprognostic (4.22e-2)" "unprognostic (2.47e-2)" 0.2 0.0 0.2 2.5 0.5 0.0 1.0 0.2 0.3 2.3 0.1 20.6 100.5 0.4 1.2 0.3 1.0 12.1 0.0 0.3 0.3 17.4 12.9 0.2 0.1 0.4 0.5 0.0 5.6 0.0 0.0 0.1 0.3 0.6 19.6 0.0 0.4 0.4 0.0 0.0 114.6 0.9 0.4 0.1 8.1 3.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.3 1.1 4.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.3 16.1 0.0 2.2 0.0 1.8 0.0 2.0 0.0 0.0 0.0 1.8 0.0 0.0 2.9 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.5 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.3 0.3 10.0 4.8 0.0 0.0 0.3 2.7 0.1 0.3 1.6 0.3 0.1 0.0 0.2 0.2 5.5 0.0 0.3 0.1 0.1 0.0 1.1 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.2 0.3 0.3 0.3 0.4 0.5 0.3 0.4 0.3 0.3 0.0 0.0 1.1 39.8 0.5 0.0 0.6 0.4 2.2 0.0 1.3 0.5 0.2 17.2 1.5 3.7 0.0 0.0 0.0 51.0 5.9 3.2 3.1 3.6 0.2 0.0 16.3 0.0 0.5 4.3 0.0 0.1 8.2 3.2 0.0 0.0 0.0 10.7 0.0 0.0 0.6 32.3 2.0 0.0 0.0 5.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 26.2 0.6 5.6 54.3 0.0 0.0 1.6 165.3 18.5 8.1 0.0 0.0 0.1 0.4 4.8 0.0 0.4 0.0 0.0 0.2 0.0 36.9 2.9 HORMAD1 "CT46, DKFZP434A1315" ENSG00000143452 "HORMA domain containing 1" Q86X24 1 150698060-150720895 "Predicted intracellular proteins" "Differentiation, Meiosis, Oogenesis, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "testis: 117.8" "Cell type enriched" "Detected in some" 4 "Spermatocytes: 727.7" "Cancer enhanced" "Detected in many" "testis cancer: 6.9" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "neutrophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A549: 5.6;HeLa: 4.9;hTCEpi: 19.4;SiHa: 6.1;SuSa: 6.5;THP-1: 11.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA028346, HPA037850" Enhanced Approved Nucleoplasm,Nucleoli Yes No "Cluster 1: Neutrophils - Mixed function" "Cluster 83: Testis - Spermatogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm Nucleoli "HPA028346: AB_2672564, HPA037850: AB_10696358" "unprognostic (7.21e-2)" "unprognostic (7.88e-2)" "unprognostic (1.05e-1)" "unprognostic (8.15e-2)" "unprognostic (9.06e-2)" "unprognostic (3.91e-3)" "unprognostic (4.08e-2)" "unprognostic (1.76e-1)" "unprognostic (1.50e-1)" "unprognostic (1.72e-1)" "unprognostic (1.56e-2)" "unprognostic (5.17e-3)" "unprognostic (3.79e-9)" "unprognostic (3.32e-2)" "unprognostic (1.18e-1)" "unprognostic (1.27e-1)" "unprognostic (3.49e-2)" 0.2 0.0 0.1 0.5 0.1 0.5 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 3.6 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.2 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.1 0.4 0.1 0.4 0.0 0.0 6.8 0.2 0.1 0.0 0.9 0.1 117.8 0.2 0.0 0.0 0.0 0.8 0.0 0.2 0.2 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 2.6 0.0 0.0 0.0 0.1 0.0 0.1 4.9 0.0 0.0 0.1 0.1 0.0 19.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.1 0.0 0.1 6.5 0.0 11.3 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.5 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.1 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.2 5.4 0.0 1.4 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 3.4 0.0 0.3 0.0 0.1 88.3 0.5 0.1 0.5 0.0 0.0 2.7 0.0 2.1 0.4 0.0 0.1 0.0 0.1 0.4 0.0 0.8 0.0 2.0 0.0 0.0 1.3 0.9 35.1 5.3 0.8 0.0 1.0 1.5 0.0 0.0 1.0 0.1 0.0 0.1 4.9 0.0 0.0 0.0 0.0 0.5 0.0 32.9 0.0 0.4 727.7 163.5 0.0 9.2 2.2 0.0 0.3 0.2 0.1 HOXA13 "HOX1, HOX1J" ENSG00000106031 "Homeobox A13" P31271 7 27193503-27200091 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 23.1;placenta: 17.1;prostate: 22.3;seminal vesicle: 23.3" "Cell type enriched" "Detected in some" 4 "Distal enterocytes: 41.3" "Cancer enhanced" "Detected in many" "prostate cancer: 10.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 26.9;HEK 293: 37.3;PC-3: 18.4;RT4: 42.1;THP-1: 18.2;U-937: 20.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046098, HPA069061" Supported "Nucleoplasm,Mitotic chromosome,Intermediate filaments" Yes NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Mitotic chromosome, Intermediate filaments" "HPA046098: AB_2679536, HPA069061: " "unprognostic (7.20e-2)" "unprognostic (1.89e-1)" "unprognostic (1.02e-1)" "unprognostic (8.04e-4)" "unprognostic (1.06e-3)" "unprognostic (2.24e-2)" "unprognostic (1.79e-1)" "unprognostic (1.40e-2)" "unprognostic (9.22e-3)" "unprognostic (7.30e-3)" "unprognostic (8.39e-3)" "unprognostic (1.54e-1)" "unprognostic (1.42e-11)" "unprognostic (2.58e-3)" "unprognostic (1.38e-1)" "unprognostic (1.72e-1)" "unprognostic (1.36e-2)" 0.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 23.1 0.0 9.9 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.1 0.0 22.3 11.9 0.0 0.0 23.3 2.1 0.3 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.1 14.1 0.0 2.2 1.6 0.0 2.5 0.2 0.0 0.1 13.2 14.4 5.1 3.3 2.8 0.2 0.0 1.6 6.2 0.7 0.0 26.9 0.0 4.3 0.0 37.3 1.9 6.9 0.2 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.1 0.0 8.7 0.0 11.8 18.4 2.7 0.6 0.0 0.1 42.1 0.7 0.0 3.3 0.0 0.3 2.0 0.0 18.2 0.0 0.5 4.5 0.3 0.1 0.0 0.0 0.0 0.0 20.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 41.3 0.0 0.0 0.6 0.1 4.0 1.1 8.4 0.0 0.0 0.0 0.1 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.6 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 5.5 0.0 0.1 0.0 0.0 0.0 0.1 2.8 0.5 0.0 0.0 0.1 0.1 0.1 0.0 10.3 3.1 HOXA2 HOX1K ENSG00000105996 "Homeobox A2" O43364 7 27100354-27102686 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 23.3;Breast myoepithelial cells: 3.8;Enteroendocrine cells: 4.8;Hepatic stellate cells: 6.4;Squamous epithelial cells: 6.3" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 16 "medulla oblongata: 4.5;pons: 3.3;spinal cord: 4.7;white matter: 4.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 14.5;HaCaT: 6.2;RPTEC TERT1: 4.9" "Region enriched" "Detected in single" 36 "pons and medulla: 5.8" "Group enriched" "Detected in some" 17 "medulla oblongata: 4.2;pons: 1.1;spinal cord: 3.0" HPA078220 Approved Nucleoplasm,Vesicles Yes NA "Cluster 1: Neutrophils - Mixed function" "Cluster 68: Epididymis - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Vesicles" "HPA078220: AB_2686880" "unprognostic (7.30e-2)" "unprognostic (4.90e-4)" "unprognostic (2.81e-1)" "unprognostic (7.43e-4)" "unprognostic (1.44e-1)" "unprognostic (2.01e-2)" "unprognostic (1.17e-1)" "unprognostic (2.96e-1)" "unprognostic (1.85e-3)" "unprognostic (1.48e-2)" "unprognostic (1.84e-1)" "unprognostic (1.58e-2)" "unprognostic (4.98e-9)" "unprognostic (1.34e-1)" "unprognostic (1.33e-1)" "unprognostic (9.36e-2)" "unprognostic (1.28e-2)" 1.9 1.0 0.0 0.6 0.0 0.0 1.6 0.0 0.0 1.6 0.0 3.3 0.9 2.0 5.1 2.3 4.1 1.0 0.2 0.0 0.0 4.4 0.2 1.7 0.2 4.5 0.2 0.6 0.3 5.7 0.0 0.0 3.3 1.7 1.8 0.0 0.0 2.1 0.7 1.6 2.6 0.9 4.7 1.2 2.2 0.1 0.1 1.8 0.8 3.0 0.6 2.0 0.9 4.3 1.1 0.6 4.0 14.5 0.0 0.0 0.0 0.2 0.1 0.0 0.1 1.6 3.4 0.1 1.5 0.1 1.8 6.2 0.2 0.0 0.0 0.0 2.0 0.0 0.1 0.2 1.8 0.1 0.3 0.8 0.0 3.1 3.1 0.0 2.5 0.3 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.9 1.0 0.7 0.0 4.9 0.5 0.9 0.0 0.2 0.0 0.9 0.2 0.0 0.0 2.5 0.0 0.2 1.1 0.5 0.0 0.0 0.1 0.0 0.6 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.2 3.3 4.7 0.1 4.3 1.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 23.3 0.0 1.2 3.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.1 1.3 2.5 4.8 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 6.4 0.1 0.1 0.0 0.0 1.3 0.0 0.0 0.7 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.1 1.1 0.5 0.0 0.0 0.0 1.0 1.9 0.0 0.0 6.3 0.3 0.0 0.1 0.0 1.7 0.7 HPF1 "C4orf27, FLJ20534" ENSG00000056050 "Histone PARylation factor 1" Q9NWY4 4 169729470-169757944 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 71.0;Distal tubular cells: 92.0;Extravillous trophoblasts: 61.2;Granulosa cells: 56.4;Hofbauer cells: 56.3;Proximal tubular cells: 63.9;Theca cells: 56.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043467 Uncertain Approved Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 7: Non-specific - Mitochondria" Cytosol "Microtubules, Cytokinetic bridge" "HPA043467: AB_10793949" "unprognostic (1.09e-1)" "unprognostic (1.15e-2)" "unprognostic (1.72e-2)" "unprognostic (1.47e-1)" "unprognostic (2.70e-1)" "unprognostic (1.09e-1)" "unprognostic (8.68e-3)" "unprognostic (2.74e-2)" "prognostic unfavorable (5.63e-4)" "prognostic favorable (7.47e-4)" "unprognostic (6.34e-2)" "unprognostic (4.55e-1)" "unprognostic (3.06e-1)" "unprognostic (2.26e-1)" "unprognostic (1.32e-1)" "unprognostic (5.51e-2)" "unprognostic (1.09e-1)" 19.3 18.6 18.6 16.4 19.9 16.8 21.2 19.6 26.0 19.6 22.0 22.0 12.2 23.3 24.8 15.7 17.1 13.1 22.5 19.2 19.7 18.1 22.1 14.3 21.1 20.2 19.3 22.7 14.4 16.0 19.5 16.8 20.9 17.3 17.7 21.3 13.2 15.7 21.3 19.6 12.8 24.8 19.6 17.5 15.8 14.1 19.6 26.9 18.8 20.9 21.1 16.8 16.8 22.2 33.7 21.0 71.2 37.7 42.6 52.4 30.3 59.9 58.8 72.8 76.7 14.3 35.5 17.5 15.7 39.2 53.3 14.7 49.5 43.6 76.7 55.1 33.7 57.0 30.0 20.5 29.9 48.7 20.1 34.1 43.2 47.1 14.5 44.1 64.1 59.1 43.7 66.2 64.4 27.3 102.7 42.4 29.2 32.2 27.0 44.7 33.8 21.2 41.9 21.9 17.2 63.1 39.7 17.2 56.3 49.1 34.0 43.1 31.3 24.8 39.2 58.4 54.3 31.3 49.8 52.4 68.3 47.0 40.3 19.3 20.0 22.4 28.7 24.0 34.6 22.0 33.0 35.1 26.1 18.1 32.1 33.3 5.3 25.4 23.7 17.9 38.1 21.9 18.6 19.9 19.6 26.0 19.2 19.7 20.2 19.3 20.9 19.6 19.6 22.2 41.6 44.8 26.4 0.0 5.7 0.0 0.0 0.0 0.0 0.0 19.9 29.6 0.0 0.0 17.3 27.6 0.0 71.0 14.3 0.0 92.0 45.7 0.0 31.9 36.9 20.1 0.0 0.0 0.0 46.3 61.2 26.1 0.0 21.9 17.7 56.4 0.0 0.0 56.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 31.1 0.0 0.0 1.6 0.0 0.0 63.9 15.3 0.0 0.0 0.0 24.3 0.0 0.0 0.0 0.0 16.3 10.5 56.0 0.0 0.0 HSD3B1 "HSD3B, HSDB3, SDR11E1" ENSG00000203857 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1" P14060 1 119507198-119515054 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism, Steroidogenesis" "Isomerase, Multifunctional enzyme, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "placenta: 77.7" "Group enriched" "Detected in some" 8 "Extravillous trophoblasts: 140.8;Syncytiotrophoblasts: 502.0" "Cancer enriched" "Detected in single" 4 "urothelial cancer: 1.6" "Region enhanced" "Detected in some" "basal ganglia: 1.0;cerebral cortex: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CACO-2: 64.1;SuSa: 26.5" "HPA043261, HPA043264, HPA044028" Supported Approved "Nucleoli,Endoplasmic reticulum,Cytokinetic bridge" Yes NA "Cluster 28: Placenta - Pregnancy" "Cluster 39: CACO-2 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoli, Endoplasmic reticulum" "Cytokinetic bridge" "HPA043261: AB_2630368, HPA043264: AB_2678398, HPA044028: AB_2678781" "unprognostic (1.53e-1)" "unprognostic (7.11e-2)" "unprognostic (1.15e-1)" "unprognostic (1.04e-1)" "prognostic favorable (4.59e-5)" 0.1 1.2 0.2 0.0 1.0 0.0 1.5 0.0 1.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 77.7 0.0 0.1 0.5 0.0 0.1 0.0 0.1 4.5 8.7 0.5 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.2 0.0 0.0 0.0 64.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 7.0 0.7 0.8 26.5 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 23.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 140.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 37.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 502.0 0.0 0.1 1.0 0.0 HSD3B2 SDR11E2 ENSG00000203859 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2" P26439 1 119414931-119423035 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Steroidogenesis "Isomerase, Multifunctional enzyme, Oxidoreductase" "Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 56 "adrenal gland: 2174.8" "Group enriched" "Detected in some" 4 "Granulosa cells: 40.6;Proximal enterocytes: 38.8;Theca cells: 68.9" "Cancer enhanced" "Detected in single" "testis cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SK-MEL-30: 1.4" "HPA043261, HPA043264, HPA044028" Supported Uncertain "Nucleoli,Endoplasmic reticulum,Cytokinetic bridge" Yes NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" "Nucleoli, Endoplasmic reticulum" "Cytokinetic bridge" "HPA043261: AB_2630368, HPA043264: AB_2678398, HPA044028: AB_2678781" "unprognostic (3.56e-1)" "unprognostic (1.85e-1)" "unprognostic (2.80e-1)" "unprognostic (2.72e-2)" "unprognostic (8.87e-2)" "unprognostic (3.91e-2)" "unprognostic (3.43e-2)" "unprognostic (1.94e-1)" "unprognostic (6.51e-2)" "unprognostic (1.97e-2)" "unprognostic (1.55e-1)" 0.2 2174.8 0.3 2.1 0.8 0.0 0.1 0.0 0.7 0.2 0.0 7.7 0.0 0.2 0.0 0.2 0.4 0.0 0.3 0.2 0.0 0.9 1.0 0.5 0.0 0.0 0.0 0.9 0.5 0.0 0.1 3.6 0.1 0.4 1.0 0.0 1.0 0.0 0.1 0.2 38.7 0.1 0.0 0.2 0.3 2.9 0.2 0.5 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 1.4 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.7 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 3.5 0.0 0.0 0.0 40.6 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.6 0.0 0.0 38.8 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 68.9 1.7 0.0 ID1 "bHLHb24, dJ857M17.1.2" ENSG00000125968 "Inhibitor of DNA binding 1, HLH protein" P41134 20 31605283-31606515 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Developmental protein, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 1667.3;Basal respiratory cells: 1443.4;Hepatic stellate cells: 2131.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.1" "Cell line enhanced" "Detected in many" "EFO-21: 509.6;HaCaT: 500.2;Hep G2: 425.3;PC-3: 515.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025915, HPA051456, HPA058518" Approved Enhanced Nucleoplasm "Intracellular and membrane" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB025915: , HPA051456: AB_2681492, HPA058518: AB_2683740" "unprognostic (3.89e-2)" "unprognostic (3.45e-2)" "unprognostic (2.62e-2)" "unprognostic (3.19e-2)" "unprognostic (1.27e-2)" "unprognostic (1.74e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (4.85e-4)" "unprognostic (2.29e-1)" "unprognostic (1.58e-1)" "unprognostic (2.14e-2)" "unprognostic (7.83e-2)" "unprognostic (1.67e-2)" "unprognostic (1.71e-3)" "unprognostic (2.97e-1)" "unprognostic (6.17e-3)" "unprognostic (3.41e-3)" 242.2 88.5 53.0 20.2 43.1 9.0 141.3 50.1 57.1 125.7 60.9 136.7 78.4 116.0 4.7 340.4 146.3 35.0 291.9 45.3 56.8 218.1 154.1 204.7 14.0 69.3 56.0 66.8 42.4 8.1 167.8 45.7 62.3 202.5 26.4 5.1 58.5 149.6 53.8 129.6 154.3 12.2 53.3 79.7 162.5 16.4 79.1 5.9 266.8 37.8 6.2 351.1 206.9 47.1 76.1 245.3 2.7 49.3 31.2 14.1 187.6 314.1 12.6 56.9 6.2 130.5 111.4 0.6 509.6 84.3 67.2 500.2 40.1 17.9 8.6 6.2 25.6 41.5 229.2 425.3 42.3 0.9 2.2 57.4 69.7 0.3 4.3 93.5 35.0 27.6 94.0 2.3 110.4 99.8 11.4 1.8 172.7 336.5 515.3 0.9 200.8 4.2 11.1 206.1 93.5 87.4 261.3 91.9 2.4 128.8 57.0 7.6 188.5 151.3 300.0 49.0 216.1 5.6 6.3 5.2 176.2 39.5 21.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 1.1 0.1 0.2 0.0 0.0 0.1 53.0 43.1 50.1 57.1 45.3 56.8 69.3 56.0 62.3 53.3 79.1 47.1 1667.3 237.2 171.7 88.2 25.1 102.3 992.2 1443.4 406.3 2.7 98.6 114.3 35.1 112.9 685.1 228.1 4.2 129.9 46.3 594.3 37.2 584.1 5.7 794.1 450.1 907.7 572.7 49.9 0.6 535.5 493.7 195.3 675.3 707.6 22.2 8.9 2131.4 109.1 25.6 0.0 0.5 557.4 321.4 72.2 52.4 8.7 28.6 38.9 90.7 92.8 8.2 85.0 1.0 4.0 0.3 257.4 924.9 0.4 26.7 519.7 579.8 7.1 168.1 8.3 13.1 229.7 206.1 3.2 53.7 455.8 87.9 89.1 39.8 15.9 389.1 591.6 IDH3G ENSG00000067829 "Isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma" P51553 X 153785766-153794523 "Citric acid cycle related proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 284.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000425, HPA002017" Supported Approved Nucleoli,Mitochondria Yes No 19000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Mitochondria" "HPA000425: AB_1079097, HPA002017: AB_1079096" "unprognostic (4.24e-2)" "unprognostic (1.43e-3)" "unprognostic (5.75e-2)" "unprognostic (1.05e-1)" "unprognostic (6.57e-2)" "unprognostic (2.25e-1)" "unprognostic (4.35e-2)" "unprognostic (1.58e-1)" "unprognostic (2.24e-2)" "unprognostic (1.59e-2)" "unprognostic (2.81e-2)" "unprognostic (1.96e-1)" "prognostic favorable (5.73e-6)" "unprognostic (1.50e-1)" "unprognostic (3.35e-1)" "unprognostic (2.91e-2)" "unprognostic (2.46e-1)" 52.0 67.1 45.5 38.5 50.0 60.3 49.9 47.8 61.3 44.1 46.5 57.2 52.3 50.7 23.5 50.2 44.8 35.0 91.9 54.9 48.8 68.5 49.2 42.0 40.3 50.5 45.7 49.3 48.3 45.5 47.9 28.3 52.3 43.8 34.6 24.4 51.7 39.9 100.5 51.7 54.7 34.5 43.9 51.8 52.2 32.1 49.1 35.2 48.0 82.9 34.9 44.3 43.2 47.2 94.9 90.0 47.3 65.9 74.4 59.4 62.0 47.3 64.1 80.5 84.3 76.0 66.5 121.4 80.2 74.7 68.2 67.2 72.6 69.2 30.0 38.9 101.7 43.0 118.9 59.0 85.5 61.6 87.5 76.1 48.0 64.4 69.4 50.4 65.3 50.3 24.7 60.4 64.7 138.5 72.0 76.0 21.6 84.2 118.0 62.7 43.3 105.8 94.4 61.1 59.5 42.8 30.2 96.3 48.0 20.8 39.6 51.9 56.0 49.9 34.1 76.8 112.5 89.0 22.6 152.1 81.8 75.8 57.6 178.1 159.3 165.8 71.8 163.9 68.0 68.5 73.2 71.2 163.1 78.9 57.9 63.7 57.8 86.5 169.6 101.3 107.5 140.1 45.5 50.0 47.8 61.3 54.9 48.8 50.5 45.7 52.3 43.9 49.1 47.2 44.4 35.3 33.8 5.5 49.2 80.9 67.5 103.9 37.5 34.9 48.4 57.9 55.1 50.1 55.0 51.5 29.2 99.8 48.2 145.0 207.4 93.4 132.0 42.2 39.4 44.6 62.3 41.4 5.6 90.5 98.7 48.2 47.9 39.8 93.8 43.6 43.2 35.4 131.0 18.5 6.4 107.0 79.3 98.0 77.0 284.2 53.4 75.6 67.6 3.7 116.4 50.8 64.9 3.0 5.0 73.5 133.8 58.6 49.7 35.6 222.4 253.1 50.7 49.3 52.6 47.4 68.2 15.9 18.3 50.3 77.4 110.8 55.2 103.0 112.7 64.2 IGFN1 "DKFZp434B1231, EEF1A2BP1" ENSG00000163395 "Immunoglobulin like and fibronectin type III domain containing 1" Q86VF2 1 201190824-201228952 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "skeletal muscle: 186.3" "Cell type enriched" "Detected in some" 4 "Skeletal myocytes: 103.8" "Cancer enriched" "Detected in some" 4 "thyroid cancer: 8.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "HeLa: 76.6" "Group enriched" "Detected in many" 7 "amygdala: 3.3;basal ganglia: 1.2;cerebral cortex: 2.9;hippocampal formation: 1.9" "Low region specificity" "Detected in some" HPA050415 Enhanced Approved "Midbody ring" Yes NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 50: Fibroblasts - ECM organization" "Midbody ring" "HPA050415: AB_2681120" "unprognostic (2.09e-1)" "unprognostic (1.63e-3)" "unprognostic (1.82e-2)" "unprognostic (3.25e-1)" "unprognostic (1.02e-2)" "unprognostic (2.00e-2)" "unprognostic (9.80e-3)" "unprognostic (1.73e-1)" "unprognostic (2.02e-2)" "unprognostic (1.51e-1)" "unprognostic (2.07e-1)" "unprognostic (3.80e-2)" "prognostic unfavorable (1.27e-8)" "unprognostic (3.55e-4)" "unprognostic (6.06e-2)" "unprognostic (1.10e-1)" "unprognostic (5.42e-2)" 0.6 0.1 0.3 0.1 0.1 0.0 0.2 0.0 0.3 0.9 0.6 0.1 0.0 10.4 15.1 0.0 0.9 0.2 0.3 1.2 0.6 0.1 0.1 0.5 0.1 0.1 0.2 0.2 7.0 0.0 0.1 0.0 0.0 0.7 0.2 0.0 0.0 0.3 186.3 0.3 0.0 0.8 0.0 0.0 0.1 2.5 0.4 0.0 14.6 0.2 0.0 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 76.6 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.8 0.0 4.9 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.3 1.2 0.6 0.1 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.4 0.1 0.0 0.0 0.1 1.5 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 22.1 0.4 1.8 1.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 9.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 103.8 0.7 0.6 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 IL18R1 "CD218a, IL-1Rrp, IL1RRP" ENSG00000115604 "Interleukin 18 receptor 1" Q13478 2 102311529-102398777 "CD markers, Enzymes, Plasma proteins, Predicted membrane proteins" "Inflammatory response" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 24.2;lymphoid tissue: 18.5" "Cell type enhanced" "Detected in many" "dendritic cells: 44.7;granulocytes: 111.2;Langerhans cells: 25.4;NK-cells: 42.2;T-cells: 25.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 45.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 27.4;HHSteC: 35.4;U-937: 52.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA007615 Approved Approved Mitochondria Yes No "Cluster 48: NK-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "HPA007615: AB_1851675" "unprognostic (3.60e-3)" "unprognostic (9.75e-3)" "unprognostic (1.12e-3)" "unprognostic (3.01e-2)" "unprognostic (2.34e-3)" "unprognostic (7.11e-2)" "unprognostic (2.95e-2)" "unprognostic (1.74e-2)" "unprognostic (3.59e-1)" "unprognostic (7.86e-2)" "unprognostic (3.40e-2)" "unprognostic (1.70e-1)" "prognostic unfavorable (4.52e-4)" "unprognostic (2.62e-1)" "unprognostic (1.62e-2)" "unprognostic (5.71e-2)" "unprognostic (2.48e-2)" 8.2 2.3 1.3 5.6 1.4 2.4 5.4 1.2 1.9 4.5 1.6 4.0 4.1 3.1 1.6 2.2 3.7 2.9 4.5 1.0 2.4 4.4 6.6 24.2 4.1 1.5 1.3 1.1 1.3 3.2 1.7 6.9 1.8 3.3 1.0 0.2 2.2 5.7 0.9 2.6 8.8 0.7 1.3 18.5 4.3 0.5 2.0 2.0 2.1 1.1 2.2 4.0 2.8 1.3 1.8 0.6 0.0 0.0 1.3 0.8 2.3 0.0 1.1 0.1 0.5 0.0 0.8 0.0 0.1 0.0 3.4 0.9 0.0 2.4 0.0 27.4 1.2 2.1 0.5 0.1 35.4 8.8 10.1 7.8 1.9 3.1 5.4 0.0 7.4 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.1 1.4 1.1 0.0 0.0 0.0 0.3 0.9 0.0 0.0 1.2 0.1 0.3 0.1 0.0 0.0 0.8 0.9 0.5 3.2 0.6 0.0 0.0 0.0 0.1 52.0 3.6 10.0 0.0 4.8 6.2 0.1 16.3 0.1 3.6 4.7 3.6 0.2 0.6 1.4 6.7 45.6 0.0 10.4 4.1 1.9 1.3 1.4 1.2 1.9 1.0 2.4 1.5 1.3 1.8 1.3 2.0 1.3 10.2 0.0 8.5 0.3 2.7 0.8 1.1 1.1 0.6 0.0 0.3 0.3 3.9 0.0 2.3 1.8 0.0 0.0 44.7 0.3 1.9 0.9 0.1 1.0 4.1 7.4 0.0 3.6 0.2 0.6 1.0 3.1 5.1 1.1 111.2 0.0 10.0 7.6 0.1 0.0 1.0 0.1 0.0 2.4 25.4 0.1 0.3 16.5 3.6 12.2 1.0 0.2 42.2 1.5 0.0 1.1 0.4 0.0 10.3 1.0 0.1 0.9 3.8 0.2 6.6 0.9 1.4 0.4 1.3 0.3 1.0 0.0 25.4 0.1 0.4 0.9 IMPA2 ENSG00000141401 "Inositol monophosphatase 2" O14732 18 11981025-12030877 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 359.1;skeletal muscle: 257.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 440.3;Extravillous trophoblasts: 272.2;Proximal tubular cells: 498.6;Squamous epithelial cells: 202.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 26.0;neutrophil: 31.3" "Group enriched" "Detected in many" 11 "dendritic cells: 9.0;granulocytes: 31.3;monocytes: 11.4" "Cell line enhanced" "Detected in many" "BEWO: 258.2;OE19: 299.8;SiHa: 155.1" "Low region specificity" "Detected in all" HPA029561 Approved Approved Nucleoplasm,Mitochondria Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Mitochondria "HPA029561: AB_10601932" "unprognostic (1.16e-1)" "unprognostic (1.28e-2)" "unprognostic (4.76e-3)" "unprognostic (2.50e-2)" "unprognostic (4.25e-2)" "unprognostic (3.25e-3)" "unprognostic (4.26e-3)" "unprognostic (4.08e-2)" "unprognostic (1.87e-1)" "unprognostic (1.96e-2)" "unprognostic (4.56e-2)" "unprognostic (4.24e-3)" "prognostic favorable (0.00e+0)" "unprognostic (1.95e-1)" "unprognostic (1.19e-1)" "unprognostic (2.08e-2)" "unprognostic (3.35e-2)" 19.8 11.1 2.5 12.3 3.2 31.5 14.8 1.8 4.4 31.0 5.3 50.0 22.4 16.2 1.7 131.2 16.3 19.9 29.5 2.5 2.4 129.4 47.4 23.2 5.7 2.2 2.4 7.8 359.1 5.3 11.1 22.0 2.1 13.7 30.7 0.8 31.0 5.9 257.1 150.0 29.2 15.6 2.3 19.0 53.7 2.9 2.6 5.0 17.4 89.8 7.3 61.0 50.8 2.3 29.3 41.7 11.3 20.4 14.1 10.5 258.2 7.2 18.4 2.9 4.2 35.4 21.7 6.1 17.4 10.1 24.1 19.8 13.2 6.9 0.8 33.5 22.5 0.0 56.0 30.6 8.3 47.5 2.3 23.9 36.3 10.0 5.2 8.5 3.9 30.7 7.4 0.0 10.7 31.8 19.4 27.1 40.5 299.8 42.7 36.0 29.6 28.6 122.1 15.6 15.0 0.3 155.1 35.8 16.2 14.5 33.3 58.5 0.0 5.6 11.5 73.7 7.3 24.5 66.3 17.9 24.0 31.7 9.6 9.4 11.4 26.0 0.7 8.7 0.3 1.5 0.7 0.2 9.0 0.3 0.3 0.5 31.3 0.1 5.8 6.7 1.1 3.1 2.5 3.2 1.8 4.4 2.5 2.4 2.2 2.4 2.1 2.3 2.6 2.3 9.2 19.2 32.7 17.6 7.8 105.5 22.7 32.1 159.4 0.7 16.8 20.2 11.6 72.9 16.1 22.0 0.0 52.5 5.8 72.9 440.3 83.4 2.8 5.7 20.2 6.9 17.5 15.3 4.7 110.6 272.2 16.1 65.2 30.4 2.5 13.4 10.0 66.8 42.5 0.0 1.8 90.2 65.1 37.7 17.0 7.1 4.7 34.2 14.2 5.6 25.5 22.3 2.1 0.5 0.5 56.1 50.1 3.8 8.6 42.9 36.9 498.6 12.3 1.0 105.2 16.0 27.6 0.8 10.1 202.1 141.4 106.3 6.1 14.0 84.4 52.8 INCENP FLJ31633 ENSG00000149503 "Inner centromere protein" Q9NQS7 11 62123998-62153169 "Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.9" "Cell type enhanced" "Detected in many" "Squamous epithelial cells: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7 "basophil: 1.2;NK-cell: 1.1" "Group enriched" "Detected in many" 7 "granulocytes: 1.2;NK-cells: 1.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013292, HPA051339, HPA070550" Enhanced Supported "Nucleoplasm,Nuclear bodies,Kinetochore,Midbody" Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies, Kinetochore" "Nucleoplasm, Midbody" "CAB013292: AB_2533405, HPA051339: AB_2732566, HPA070550: AB_2686279" "unprognostic (6.31e-2)" "unprognostic (7.29e-2)" "unprognostic (1.65e-3)" "unprognostic (7.35e-2)" "unprognostic (3.18e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.25e-4)" "prognostic unfavorable (8.58e-4)" "unprognostic (1.63e-2)" "unprognostic (4.37e-2)" "prognostic unfavorable (5.76e-5)" "unprognostic (1.74e-2)" "unprognostic (1.08e-3)" "unprognostic (1.17e-3)" "unprognostic (1.22e-1)" "unprognostic (1.36e-1)" "unprognostic (2.78e-3)" 3.1 2.5 2.7 7.5 1.1 20.9 2.8 6.2 3.0 4.6 0.0 4.8 6.8 3.0 8.1 14.0 3.5 2.2 2.8 2.9 0.5 2.4 1.9 3.0 11.6 1.6 0.8 3.8 3.1 3.1 1.5 4.1 1.3 2.5 3.6 3.4 6.1 2.9 4.2 7.9 5.7 3.4 0.1 5.5 4.5 6.4 0.5 17.8 5.1 3.4 8.2 2.8 5.5 1.2 74.3 69.4 51.6 45.5 6.8 8.4 28.1 47.6 21.2 44.4 28.3 37.0 50.7 70.0 36.2 16.0 46.2 72.6 52.2 28.4 31.8 60.5 36.6 45.7 68.0 29.6 2.7 53.5 62.1 4.3 6.5 41.3 23.6 6.8 25.8 50.2 48.8 57.6 25.3 59.7 85.0 43.3 56.2 28.0 34.4 79.3 66.4 53.4 12.0 35.8 40.1 42.2 46.8 30.8 27.9 19.8 48.2 19.4 28.5 41.8 51.9 59.8 50.0 29.7 48.3 75.8 23.5 34.7 50.6 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 2.7 1.1 6.2 3.0 2.9 0.5 1.6 0.8 1.3 0.1 0.5 1.2 1.2 3.2 2.3 1.3 3.4 5.6 0.8 1.0 2.8 2.4 1.1 0.6 1.3 0.0 3.7 0.0 0.0 4.2 4.2 5.4 0.0 1.9 1.0 2.0 2.1 1.5 0.0 10.9 3.3 2.5 7.1 1.9 9.2 2.7 3.8 5.7 0.0 0.7 4.2 0.0 2.5 3.4 0.0 0.9 1.6 0.5 2.8 3.3 3.6 1.0 5.0 1.5 3.1 2.0 1.5 2.2 1.6 1.5 10.9 1.2 1.3 0.3 2.6 2.3 0.0 1.9 4.3 6.5 7.8 15.1 3.3 2.2 3.7 1.9 4.8 1.1 ING4 "my036, p29ING4" ENSG00000111653 "Inhibitor of growth family member 4" Q9UNL4 12 6650301-6663142 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Chromatin regulator" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031817, HPA057338" Approved Supported Nucleoplasm Yes No "Cluster 24: B-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA031817: AB_2674056, HPA057338: AB_2683412" "unprognostic (2.95e-1)" "unprognostic (1.92e-2)" "unprognostic (1.40e-1)" "unprognostic (2.71e-3)" "unprognostic (9.44e-2)" "unprognostic (5.76e-3)" "unprognostic (1.65e-2)" "prognostic favorable (5.16e-4)" "unprognostic (3.67e-2)" "unprognostic (1.80e-1)" "unprognostic (7.66e-3)" "unprognostic (1.52e-1)" "unprognostic (4.32e-2)" "unprognostic (1.31e-1)" "unprognostic (9.88e-2)" "unprognostic (2.17e-1)" "unprognostic (1.42e-2)" 22.9 26.4 43.8 15.5 44.5 11.6 27.9 45.8 51.7 34.9 40.7 33.7 17.9 27.4 30.7 22.8 27.4 18.1 23.9 44.0 43.9 29.7 25.7 18.6 27.6 44.9 44.0 31.3 19.7 32.0 27.7 21.6 44.8 33.0 21.8 22.3 25.9 23.1 19.3 31.0 26.7 22.5 44.8 37.7 26.9 20.4 44.7 38.5 34.9 23.8 24.5 29.5 27.2 49.3 9.2 12.3 35.8 17.0 27.3 26.9 22.9 12.0 19.4 19.6 23.4 5.6 41.1 15.9 7.8 16.8 15.6 14.3 17.8 14.1 21.7 31.1 26.4 22.9 22.5 11.5 16.0 9.1 10.4 27.3 32.3 10.4 13.3 63.4 29.8 30.6 10.9 8.9 19.0 6.6 33.2 13.9 52.8 20.3 11.7 30.9 18.8 17.0 24.7 10.4 14.7 38.3 18.6 6.2 23.2 51.5 8.2 25.0 22.7 8.1 16.1 9.1 7.9 10.7 15.6 21.6 21.6 14.0 8.3 32.2 31.1 26.8 33.5 43.5 31.2 30.9 27.8 28.7 34.3 48.2 37.9 32.9 20.1 38.0 51.0 26.5 30.9 37.9 43.8 44.5 45.8 51.7 44.0 43.9 44.9 44.0 44.8 44.8 44.7 49.3 20.5 22.4 19.0 15.0 26.8 8.2 11.1 19.1 13.6 31.2 22.2 27.6 10.9 17.2 17.9 18.4 18.8 43.3 37.0 14.4 29.4 25.0 2.0 17.1 21.6 22.4 25.2 18.1 23.1 8.1 11.7 21.8 10.2 14.8 27.9 40.7 20.0 8.9 24.6 35.3 23.0 18.6 30.5 16.6 12.4 6.7 34.5 27.0 10.6 13.1 32.6 34.6 52.5 18.6 20.7 11.9 16.9 37.6 11.7 11.8 21.3 24.4 12.5 26.4 32.9 13.6 21.2 20.7 19.1 9.9 10.1 30.6 22.3 31.8 14.6 9.7 INTS8 "C8orf52, FLJ20530, INT8, MGC131633" ENSG00000164941 "Integrator complex subunit 8" Q75QN2 8 94813311-94881746 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057299 Approved Approved Nucleoplasm Yes No "Cluster 26: Non-specific - Mitochondria" "Cluster 23: Testis - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA057299: AB_2683403" "unprognostic (1.08e-2)" "unprognostic (3.12e-2)" "unprognostic (1.28e-1)" "unprognostic (5.86e-2)" "unprognostic (1.96e-1)" "unprognostic (4.81e-2)" "prognostic unfavorable (2.54e-6)" "unprognostic (3.07e-2)" "unprognostic (6.87e-2)" "unprognostic (9.77e-3)" "unprognostic (4.84e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.24e-1)" "unprognostic (5.60e-2)" "unprognostic (1.11e-1)" "unprognostic (3.96e-2)" 8.8 7.5 4.4 13.9 4.8 15.5 8.1 8.3 6.4 14.5 6.9 12.8 7.8 13.2 4.2 10.5 9.5 7.3 10.2 4.8 6.4 6.4 8.9 7.5 17.4 5.7 4.4 11.4 13.5 10.1 8.3 9.4 4.6 10.4 14.8 10.3 11.0 8.7 12.6 10.3 10.6 13.6 4.0 9.9 10.6 30.6 6.3 20.6 8.8 12.0 13.6 10.4 10.4 6.1 52.4 31.9 49.2 43.4 17.7 41.7 25.5 27.5 26.0 35.7 33.0 22.5 38.0 52.3 25.2 20.7 44.3 31.5 61.3 29.2 47.6 58.1 28.8 45.7 19.3 22.1 21.1 24.6 31.7 17.1 13.5 34.7 29.6 40.8 40.1 35.1 44.4 38.9 22.0 34.5 53.7 20.4 28.1 114.9 55.8 42.7 19.7 29.0 30.0 26.6 34.6 18.4 26.8 7.7 24.1 40.3 37.3 31.6 28.1 16.1 18.9 31.1 25.1 22.0 43.0 45.2 21.6 49.4 32.2 2.1 9.6 15.1 4.6 6.8 7.5 13.4 10.8 11.8 9.3 10.4 11.0 6.5 9.3 9.6 6.6 5.5 10.0 4.5 4.4 4.8 8.3 6.4 4.8 6.4 5.7 4.4 4.6 4.0 6.3 6.1 11.0 16.0 8.6 16.6 19.4 5.9 11.6 9.1 9.6 13.7 6.1 4.6 8.3 5.7 11.6 7.3 33.3 10.0 9.7 10.3 3.9 8.3 36.0 15.0 12.1 11.8 18.0 17.7 44.8 13.4 12.9 10.8 8.6 6.1 12.7 15.2 8.9 5.5 9.5 28.6 40.9 11.8 8.2 11.6 6.6 6.4 16.1 14.0 7.2 25.3 21.6 8.0 16.5 33.2 31.2 10.9 14.6 16.1 18.0 8.8 9.5 5.1 19.7 18.9 6.6 10.6 13.1 54.7 32.5 9.0 7.0 8.5 14.2 11.0 11.1 8.1 INTS9 "CPSF2L, FLJ10871, RC-74" ENSG00000104299 "Integrator complex subunit 9" Q9NV88 8 28767661-28890242 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 28.7;Excitatory neurons: 29.5;Inhibitory neurons: 31.3;Oligodendrocyte precursor cells: 32.2;Oligodendrocytes: 39.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051615, HPA066822" Enhanced Nucleoplasm Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA051615: AB_2681552, HPA066822: AB_2685729" "unprognostic (2.19e-2)" "unprognostic (1.45e-2)" "unprognostic (1.79e-2)" "prognostic favorable (9.45e-4)" "unprognostic (2.46e-1)" "unprognostic (1.56e-3)" "unprognostic (6.91e-3)" "prognostic favorable (7.71e-4)" "unprognostic (3.64e-2)" "unprognostic (5.01e-2)" "unprognostic (4.72e-2)" "unprognostic (2.48e-3)" "prognostic favorable (1.91e-5)" "unprognostic (2.51e-2)" "unprognostic (2.73e-1)" "unprognostic (1.32e-1)" "unprognostic (1.52e-1)" 8.6 22.0 7.9 11.1 8.9 6.8 8.3 8.7 9.4 9.1 10.5 8.8 6.9 9.2 11.3 11.1 9.7 6.7 12.2 7.9 8.6 10.7 5.9 8.8 14.6 8.5 8.8 8.2 9.7 9.5 12.5 7.9 8.6 9.1 9.3 10.5 8.9 7.2 11.6 9.9 9.6 9.0 8.6 15.7 9.4 12.8 8.9 17.5 10.6 6.9 17.9 11.0 8.7 9.4 24.7 17.0 20.1 21.4 24.3 11.3 8.8 11.1 15.1 19.0 20.9 11.9 13.4 24.4 15.2 11.4 17.0 20.1 39.2 22.7 26.1 10.3 16.1 24.4 9.5 21.0 17.6 12.3 18.2 13.0 16.0 22.9 16.3 10.2 23.8 34.5 52.2 13.7 12.8 13.5 57.5 22.3 27.4 28.8 10.9 36.5 23.3 12.8 13.4 16.8 14.4 26.4 11.5 14.8 20.5 16.0 14.4 13.8 14.1 10.9 27.6 18.7 14.2 7.0 5.3 29.8 16.8 20.3 15.8 17.0 20.6 19.0 17.3 23.0 16.1 18.0 15.1 19.3 29.1 19.5 13.4 14.5 8.3 25.1 17.4 15.4 20.3 12.0 7.9 8.9 8.7 9.4 7.9 8.6 8.5 8.8 8.6 8.6 8.9 9.4 3.6 6.4 4.2 28.7 10.9 2.3 2.4 4.7 1.8 2.1 2.7 2.3 5.8 5.7 3.7 3.7 6.2 7.7 6.1 2.8 1.9 3.7 8.3 4.8 6.2 4.6 6.0 4.2 29.5 5.1 4.8 4.7 9.2 5.9 0.0 6.7 3.9 2.5 7.5 1.7 31.3 3.6 4.1 3.8 6.1 4.1 7.8 4.1 3.6 23.4 5.4 2.4 4.1 32.2 39.9 4.9 1.7 4.5 4.3 1.9 3.3 4.3 3.4 6.1 0.0 4.2 4.0 5.1 3.5 7.7 3.0 4.8 5.4 11.2 3.5 1.7 IP6K3 "IHPK3, INSP6K3" ENSG00000161896 "Inositol hexakisphosphate kinase 3" Q96PC2 6 33721662-33746905 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "skeletal muscle: 308.1;tongue: 83.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 8.5;Cardiomyocytes: 11.2;Hepatocytes: 8.9;Horizontal cells: 10.1;Oligodendrocytes: 15.3;Proximal tubular cells: 8.2;Skeletal myocytes: 51.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 21.9;HSkMC: 7.9;LHCN-M2: 36.2;RH-30: 15.7" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA053644, HPA062531" Enhanced Approved Nucleoplasm,Cytosol Yes NA "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" Nucleoplasm Cytosol "HPA053644: AB_2682214, HPA062531: " "unprognostic (3.23e-2)" "unprognostic (2.87e-1)" "unprognostic (2.07e-5)" "unprognostic (1.07e-3)" "unprognostic (2.20e-1)" "unprognostic (5.10e-3)" "unprognostic (1.38e-1)" "unprognostic (1.75e-1)" "unprognostic (2.45e-1)" "unprognostic (2.47e-2)" "unprognostic (1.24e-2)" "unprognostic (2.94e-3)" "prognostic unfavorable (6.09e-4)" "unprognostic (1.63e-2)" "unprognostic (2.01e-1)" "unprognostic (2.66e-3)" "unprognostic (1.33e-1)" 1.4 0.7 4.8 0.4 15.5 0.0 1.3 12.2 9.5 1.9 5.7 6.8 0.4 3.8 0.1 6.5 1.2 0.1 29.6 5.9 8.8 6.0 18.8 5.2 0.1 14.7 13.1 0.5 0.6 0.0 0.5 4.7 15.0 5.3 0.6 0.9 2.7 1.6 308.1 0.7 2.3 1.8 7.0 3.3 1.6 0.2 12.4 0.5 12.9 83.3 0.0 2.4 1.9 27.1 0.1 0.0 0.5 0.0 0.0 0.1 3.6 0.1 0.4 0.3 2.6 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.1 21.9 0.0 0.1 7.9 1.2 0.1 0.6 0.1 0.0 0.0 0.0 0.0 36.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 15.7 0.0 0.0 0.0 0.4 0.1 0.0 0.7 0.5 5.3 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 15.5 12.2 9.5 5.9 8.8 14.7 13.1 15.0 7.0 12.4 27.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.2 0.0 8.5 0.4 0.4 11.2 0.0 1.4 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.4 5.0 0.2 0.0 0.0 0.2 0.0 0.1 0.9 0.0 0.2 0.0 0.0 0.0 8.9 0.3 10.1 0.1 0.0 0.0 0.0 0.0 0.1 0.9 0.1 0.0 0.0 0.0 1.1 0.0 0.0 15.3 0.0 0.0 0.0 0.0 0.0 0.0 8.2 1.0 0.4 6.6 51.7 1.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.2 IQCB1 "KIAA0036, NPHP5, SLSN5" ENSG00000173226 "IQ motif containing B1" Q15051 3 121769761-121835079 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" Calmodulin-binding "Ciliopathy, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 155.3;Spermatogonia: 96.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 131.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042028 Approved Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 43: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA042028: AB_2677806" "unprognostic (3.82e-2)" "prognostic favorable (1.77e-4)" "unprognostic (2.16e-1)" "unprognostic (4.10e-2)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" "prognostic unfavorable (3.08e-5)" "prognostic favorable (3.67e-4)" "unprognostic (1.42e-1)" "unprognostic (1.87e-1)" "unprognostic (1.70e-1)" "unprognostic (6.78e-3)" "unprognostic (1.50e-3)" "unprognostic (2.59e-3)" "unprognostic (2.75e-1)" "unprognostic (1.67e-1)" "unprognostic (4.75e-3)" 11.6 11.2 9.6 14.7 10.0 20.4 23.1 11.0 10.5 15.7 10.8 13.0 12.0 15.5 19.7 12.5 16.6 12.1 9.7 10.1 10.1 12.2 8.9 12.3 24.3 9.7 9.5 17.9 18.3 13.9 15.3 11.5 9.5 15.9 16.2 18.9 15.6 15.5 11.4 15.5 14.1 11.8 9.7 18.3 12.3 28.9 10.4 22.1 10.5 5.7 25.7 14.2 13.7 11.0 38.3 10.1 48.9 55.5 7.5 11.6 57.2 17.4 10.8 19.7 23.8 33.6 18.1 76.8 23.9 10.1 30.2 28.7 30.5 14.5 29.3 15.1 23.8 51.2 22.2 28.7 20.0 64.1 14.8 7.4 27.2 13.7 30.3 10.2 15.2 32.4 31.0 27.9 22.3 19.3 41.7 44.5 40.1 22.6 18.1 40.4 23.4 24.9 11.4 16.9 26.0 20.9 17.3 12.2 31.3 16.0 10.8 49.4 12.9 18.5 22.4 9.1 23.4 66.4 44.9 131.2 17.9 29.0 17.1 3.2 6.6 11.7 7.2 12.3 10.5 22.8 9.8 9.0 9.6 21.6 11.5 7.2 2.8 12.2 14.1 8.7 11.7 6.4 9.6 10.0 11.0 10.5 10.1 10.1 9.7 9.5 9.5 9.7 10.4 11.0 15.8 6.4 15.0 48.3 28.4 18.9 19.2 20.0 19.9 15.2 19.6 17.3 8.4 11.5 26.5 11.0 27.1 26.6 21.9 7.7 3.9 11.1 3.7 31.1 12.7 11.2 7.2 21.5 60.1 12.9 8.2 15.4 11.7 12.6 8.8 21.9 6.8 6.2 10.5 13.5 66.8 8.6 20.3 9.8 14.1 7.4 15.5 11.3 14.2 51.5 15.8 12.8 17.5 49.3 59.5 13.9 8.2 13.5 45.2 15.7 7.9 7.5 69.2 27.7 13.1 17.8 15.9 155.3 96.5 16.2 20.6 14.1 19.9 8.4 11.9 16.3 IQCE KIAA1023 ENSG00000106012 "IQ motif containing E" Q6IPM2 7 2558972-2614733 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Early spermatids: 410.0;Late spermatids: 419.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.6" "Group enriched" "Detected in many" 4 "dendritic cells: 2.6;granulocytes: 4.6;monocytes: 1.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA019515 Approved Approved Nucleoplasm,Cytosol Yes No "Cluster 6: Non-specific - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA019515: AB_1851855" "unprognostic (2.29e-1)" "unprognostic (2.54e-1)" "unprognostic (3.78e-2)" "prognostic favorable (5.91e-4)" "unprognostic (7.96e-3)" "unprognostic (3.75e-1)" "unprognostic (2.54e-3)" "unprognostic (1.31e-1)" "unprognostic (4.04e-3)" "unprognostic (1.30e-2)" "unprognostic (1.66e-2)" "unprognostic (2.84e-1)" "unprognostic (2.04e-2)" "unprognostic (2.82e-2)" "unprognostic (6.97e-2)" "unprognostic (7.56e-3)" "unprognostic (3.13e-2)" 4.5 6.6 19.3 6.5 16.7 5.6 6.2 9.6 19.3 7.5 22.5 9.4 12.0 8.3 10.3 5.3 14.6 7.2 6.6 17.3 16.3 6.6 3.3 7.5 4.3 16.5 18.6 7.7 7.6 11.0 14.4 3.5 11.3 7.8 8.7 9.8 9.1 9.3 4.9 7.3 10.1 6.6 13.3 4.6 9.6 31.7 18.6 4.3 10.5 5.5 3.5 5.7 4.3 15.1 35.5 18.2 7.0 23.0 9.2 13.4 13.2 7.2 11.7 8.8 9.4 9.5 19.6 2.5 8.0 16.7 19.7 17.9 5.1 7.4 8.9 6.3 10.9 4.9 21.9 2.6 6.8 12.8 6.4 5.8 13.5 8.3 9.9 10.4 10.3 8.9 15.4 4.5 11.8 35.8 5.2 8.6 6.6 15.7 12.4 4.9 8.4 8.8 10.1 15.9 15.7 18.7 8.2 33.9 7.1 4.9 41.5 17.1 10.3 7.6 15.7 30.2 12.2 4.9 8.0 0.5 15.3 8.5 22.1 0.8 0.8 2.3 0.6 1.2 0.2 0.2 0.3 0.3 0.3 0.3 0.2 0.6 4.6 0.2 0.4 2.6 0.2 0.2 19.3 16.7 9.6 19.3 17.3 16.3 16.5 18.6 11.3 13.3 18.6 15.1 4.8 12.8 14.3 14.4 2.1 5.5 5.7 5.3 6.2 8.9 12.3 7.9 9.1 14.3 11.4 12.9 60.5 4.1 13.8 27.4 17.6 20.6 410.0 44.8 15.3 5.7 8.4 1.7 16.6 19.7 10.0 7.0 24.5 9.4 1.3 7.6 6.4 2.8 10.1 20.2 17.4 12.3 12.2 8.1 5.3 419.3 14.0 9.3 0.0 3.7 12.0 14.9 12.3 4.5 4.2 24.1 18.9 15.4 8.0 5.4 12.1 9.5 58.7 36.7 19.7 7.8 6.6 40.9 43.8 3.5 4.3 1.9 4.9 11.2 12.4 4.0 IQGAP3 ENSG00000183856 "IQ motif containing GTPase activating protein 3" Q86VI3 1 156525405-156572604 "Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.5" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 11.2;Late spermatids: 26.6;Undifferentiated cells: 7.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "HPA030142, HPA030143" Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA030142: AB_10600108, HPA030143: AB_10601104" "unprognostic (9.99e-3)" "unprognostic (5.24e-2)" "unprognostic (3.26e-1)" "unprognostic (1.55e-3)" "unprognostic (1.52e-1)" "unprognostic (4.69e-3)" "prognostic unfavorable (8.94e-6)" "unprognostic (1.86e-3)" "unprognostic (1.72e-1)" "unprognostic (1.98e-1)" "unprognostic (6.35e-3)" "unprognostic (1.03e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.46e-2)" "unprognostic (1.53e-1)" "unprognostic (6.30e-2)" "unprognostic (6.81e-2)" 0.7 0.7 0.2 2.2 0.4 15.5 0.6 0.0 0.6 1.1 0.2 4.1 6.6 0.5 1.1 5.2 0.2 0.7 0.4 0.5 0.1 0.6 0.6 1.6 1.6 0.9 0.4 0.1 0.2 0.1 0.1 2.8 0.9 0.4 5.0 0.0 1.0 0.1 0.3 3.7 5.7 2.9 0.0 0.8 4.6 3.8 0.6 3.4 0.2 0.0 2.2 0.9 2.1 0.4 59.2 28.4 25.6 18.1 1.6 4.0 12.4 43.1 28.3 41.0 36.6 32.4 52.5 5.2 15.6 25.2 21.6 54.6 17.5 22.1 36.3 0.1 15.7 7.8 62.6 16.1 0.2 9.7 0.1 1.2 2.5 34.3 50.0 10.0 24.1 12.5 16.1 8.1 30.2 31.2 5.7 13.7 18.6 57.7 28.0 18.9 28.8 6.1 10.4 20.3 16.3 25.2 38.7 44.9 14.9 29.8 35.8 25.6 16.8 36.8 43.7 30.4 51.4 4.0 2.1 2.4 12.4 15.1 42.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.2 0.4 0.0 0.6 0.5 0.1 0.9 0.4 0.9 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.4 1.3 0.1 0.4 0.6 0.0 1.4 1.3 1.0 2.8 0.1 0.0 0.0 2.2 0.1 3.9 0.0 0.3 6.5 0.5 0.7 0.6 1.2 6.5 0.7 0.0 3.6 0.9 11.2 1.4 0.0 4.4 2.5 0.4 3.9 0.0 0.2 3.7 0.0 1.3 6.1 26.6 0.3 1.9 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.5 0.4 0.8 0.4 0.0 0.0 0.0 0.0 1.4 6.4 2.6 3.6 1.0 0.8 0.2 0.3 7.4 0.4 ITGA2 CD49B ENSG00000164171 "Integrin subunit alpha 2" P17301 5 52989340-53094779 "Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 406.2;Oligodendrocytes: 370.9;Pancreatic endocrine cells: 558.7;Prostatic glandular cells: 299.3;Urothelial cells: 363.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 91.4;HaCaT: 92.5;hTERT-RPE1: 83.2;HUVEC TERT2: 83.5;TIME: 71.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017690, HPA060991, HPA063556" Enhanced Approved Nucleoplasm,Cytosol Yes No 43000000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm Cytosol "CAB017690: AB_1124939, HPA060991: AB_2684405, HPA063556: AB_2685040" "unprognostic (8.35e-2)" "unprognostic (1.33e-1)" "unprognostic (3.85e-3)" "unprognostic (1.07e-1)" "unprognostic (1.22e-1)" "unprognostic (3.70e-2)" "unprognostic (2.67e-3)" "unprognostic (2.38e-2)" "unprognostic (1.87e-1)" "unprognostic (1.69e-2)" "prognostic unfavorable (1.02e-5)" "unprognostic (4.27e-1)" "unprognostic (3.88e-2)" "unprognostic (2.87e-2)" "unprognostic (1.84e-1)" "unprognostic (1.30e-1)" "unprognostic (1.11e-1)" 1.4 12.8 2.4 4.9 6.7 0.4 7.8 4.4 3.7 5.0 0.9 6.1 7.7 4.9 7.4 11.0 2.6 9.0 1.1 2.4 4.2 9.8 0.5 12.5 0.9 4.8 4.9 1.0 1.6 9.3 1.2 4.8 5.4 6.6 5.9 2.4 10.4 11.1 0.5 17.1 7.7 2.4 3.3 6.8 7.5 0.4 4.8 4.3 2.3 0.7 4.6 15.6 8.0 12.9 60.4 15.4 1.3 0.8 3.9 7.1 4.5 60.2 91.4 2.2 3.6 29.0 41.8 0.1 9.8 25.4 33.5 92.5 4.9 67.1 8.5 0.0 4.4 4.3 3.7 17.5 13.3 0.7 1.3 2.9 11.4 59.2 10.5 83.2 83.5 3.1 0.1 0.2 1.6 11.4 0.6 0.1 3.7 15.7 29.6 0.0 0.4 0.1 18.9 32.0 0.6 3.2 3.2 4.1 6.1 2.3 9.6 0.2 71.2 10.8 6.3 1.7 12.1 0.0 0.1 0.1 64.0 0.0 48.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.4 6.7 4.4 3.7 2.4 4.2 4.8 4.9 5.4 3.3 4.8 12.9 7.4 57.7 13.7 9.1 0.6 151.0 406.2 141.3 56.9 2.7 24.4 39.0 1.3 15.7 133.2 53.3 4.2 1.9 0.9 23.2 9.8 144.0 0.1 20.3 5.0 39.0 13.8 0.0 0.5 169.3 2.2 11.6 13.3 90.6 1.3 45.4 5.3 0.2 0.3 0.0 0.9 37.8 20.3 0.0 6.1 0.2 1.2 2.5 12.4 14.0 1.1 14.7 0.0 0.0 370.9 558.7 20.3 0.0 2.6 299.3 20.6 3.8 103.6 4.3 0.0 4.4 12.1 0.0 1.3 57.0 37.2 0.4 5.8 23.7 30.9 363.9 JPH3 "CAGL237, HDL2, JP-3, JP3, TNRC22" ENSG00000154118 "Junctophilin 3" Q8WXH2 16 87601835-87698156 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 59.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 24.4;Cone photoreceptor cells: 22.9;Early spermatids: 41.1;Excitatory neurons: 33.2;Horizontal cells: 50.5;Inhibitory neurons: 28.7;Late spermatids: 14.4" "Cancer enhanced" "Detected in some" "glioma: 1.7" "Group enriched" "Detected in all" 5 "amygdala: 17.1;basal ganglia: 24.6;cerebral cortex: 59.1;hippocampal formation: 42.7;white matter: 20.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 6.5;NTERA-2: 5.7;SH-SY5Y: 7.2;SiHa: 5.0;U-2 OS: 22.5" "Low region specificity" "Detected in all" HPA076304 Approved Nucleoplasm,Cytosol Yes No "Cluster 10: Brain - Neuronal signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm Cytosol "HPA076304: AB_2686793" "unprognostic (8.97e-3)" "unprognostic (3.17e-2)" "unprognostic (1.57e-3)" "unprognostic (4.82e-3)" "unprognostic (3.43e-1)" "unprognostic (9.12e-2)" "unprognostic (1.68e-2)" "unprognostic (8.10e-2)" "unprognostic (5.53e-2)" "unprognostic (1.48e-1)" "unprognostic (5.61e-3)" "unprognostic (2.80e-2)" "unprognostic (1.28e-4)" "unprognostic (3.01e-2)" "unprognostic (2.09e-1)" "unprognostic (1.87e-2)" "unprognostic (1.36e-2)" 0.2 1.3 17.1 0.2 24.6 0.0 0.1 1.1 59.1 0.7 0.0 1.1 0.1 0.2 0.0 0.6 0.4 0.0 0.1 42.7 5.6 0.0 0.1 0.1 0.0 6.4 5.8 0.1 0.3 0.0 14.1 0.0 1.1 0.2 0.0 1.8 0.0 0.3 0.0 0.1 0.5 0.0 1.1 0.1 0.5 1.4 1.1 0.0 0.1 0.0 0.0 0.1 0.3 20.6 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 3.0 0.0 0.9 0.0 1.2 0.0 0.0 0.1 0.9 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 6.5 0.0 0.0 5.7 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.5 7.2 5.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 22.5 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.1 24.6 1.1 59.1 42.7 5.6 6.4 5.8 1.1 1.1 1.1 20.6 0.0 0.0 0.0 2.3 0.1 0.0 0.2 0.0 0.0 24.4 0.0 0.0 3.7 0.0 0.0 0.0 22.9 0.0 0.0 0.1 0.0 0.0 41.1 0.0 0.0 0.8 0.0 0.0 33.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 2.2 0.0 0.1 50.5 28.7 0.0 0.0 0.0 0.0 14.4 0.3 0.0 0.0 0.0 0.0 1.3 0.0 10.6 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.6 0.0 0.2 0.1 1.1 3.7 0.0 0.0 0.1 0.1 0.5 0.0 0.1 JRKL HHMJG ENSG00000183340 "JRK like" Q9Y4A0 11 96389989-96507574 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 171.1;Late spermatids: 49.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046184, HPA060341" Uncertain Approved "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 24: NB-4 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Cytokinetic bridge" "HPA046184: AB_10963576, HPA060341: AB_2732646" "unprognostic (4.59e-3)" "unprognostic (9.21e-2)" "unprognostic (3.42e-1)" "unprognostic (1.80e-2)" "unprognostic (6.90e-2)" "unprognostic (2.44e-1)" "unprognostic (5.00e-3)" "unprognostic (4.94e-2)" "unprognostic (7.55e-3)" "unprognostic (6.12e-2)" "unprognostic (3.99e-3)" "unprognostic (1.31e-1)" "unprognostic (3.20e-3)" "unprognostic (6.21e-2)" "unprognostic (1.21e-1)" "unprognostic (2.97e-1)" "unprognostic (9.57e-3)" 7.4 6.2 4.2 7.6 4.4 1.7 8.8 4.5 4.9 9.8 4.3 7.1 7.2 8.4 7.4 5.9 10.1 6.6 6.1 4.0 5.3 6.7 4.2 6.2 9.3 4.7 4.7 13.2 5.1 6.9 4.1 8.4 4.8 8.4 9.0 11.1 8.8 6.9 4.1 7.8 8.4 6.9 4.4 7.5 8.6 11.7 4.7 9.6 9.6 4.4 9.2 6.8 6.0 5.3 9.4 5.8 11.8 8.9 23.1 25.7 8.6 15.6 10.5 10.9 14.2 9.8 22.2 12.8 22.3 14.4 13.9 14.5 5.9 10.6 12.6 13.9 5.5 11.9 17.0 7.5 18.7 6.8 7.4 12.2 16.3 15.8 19.6 20.3 10.0 14.5 6.4 5.5 17.9 1.9 8.8 19.8 1.8 16.7 7.9 8.9 11.5 10.5 13.5 9.7 4.7 8.6 9.1 6.2 7.1 11.0 7.6 9.1 12.4 21.1 9.4 18.6 6.4 4.7 10.9 7.5 9.8 10.9 9.2 3.3 2.6 2.6 1.6 2.1 2.3 2.2 2.6 2.0 2.6 1.6 3.2 2.9 0.9 1.8 2.5 4.1 1.3 1.6 4.2 4.4 4.5 4.9 4.0 5.3 4.7 4.7 4.8 4.4 4.7 5.3 6.2 9.6 5.8 4.2 5.0 4.7 10.3 6.6 2.8 7.4 7.6 8.9 6.8 15.7 12.0 0.0 4.2 6.0 11.7 9.0 1.9 11.5 171.1 9.9 13.6 5.8 6.0 4.8 3.4 5.1 5.0 9.9 7.1 6.8 3.8 5.0 6.4 2.2 5.0 8.4 3.0 10.5 4.1 7.2 5.2 49.3 8.4 6.0 1.8 1.0 6.9 5.2 6.2 3.5 8.2 8.2 4.5 9.4 2.4 8.4 7.6 6.1 25.3 12.3 0.0 6.0 9.6 9.9 4.9 5.3 6.0 4.0 4.8 7.5 9.7 8.4 JUN "AP-1, c-Jun" ENSG00000177606 "Jun proto-oncogene, AP-1 transcription factor subunit" P05412 1 58776845-58784048 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 295.6" "Low region specificity" "Detected in all" "CAB003801, CAB007780, HPA031174, HPA059474" Enhanced Enhanced Nucleoplasm Yes No "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB003801: AB_365485, CAB007780: AB_562268, HPA031174: , HPA059474: AB_2684030" "unprognostic (2.06e-2)" "unprognostic (1.76e-2)" "unprognostic (1.34e-1)" "unprognostic (7.85e-2)" "unprognostic (1.60e-1)" "unprognostic (1.70e-1)" "unprognostic (4.11e-2)" "unprognostic (5.21e-2)" "unprognostic (1.24e-1)" "unprognostic (5.00e-2)" "unprognostic (2.14e-1)" "unprognostic (2.82e-1)" "unprognostic (5.15e-2)" "unprognostic (1.45e-1)" "unprognostic (2.83e-1)" "unprognostic (2.37e-1)" "unprognostic (2.81e-3)" 331.1 92.7 34.4 36.3 37.0 129.1 308.2 41.6 38.1 172.0 28.0 154.7 34.7 116.4 15.8 100.2 314.1 89.6 158.4 39.1 37.2 94.0 205.2 202.8 52.1 32.7 30.7 197.0 192.2 59.8 75.0 40.1 30.5 153.4 55.0 29.7 154.5 71.7 114.3 286.6 79.1 113.3 34.3 62.0 239.5 20.2 33.8 71.5 189.5 158.8 5.4 156.4 164.5 36.9 49.8 2.8 22.4 2.6 35.3 40.0 0.2 69.4 27.0 57.1 34.3 10.1 3.5 1.7 23.8 57.4 133.6 12.9 2.0 27.7 40.6 29.8 128.9 0.5 1.9 16.9 29.4 5.3 10.2 42.0 74.0 78.1 34.0 27.7 47.2 2.4 15.6 29.6 24.9 8.0 2.5 32.5 13.5 34.6 32.2 1.1 295.6 7.0 60.7 5.8 43.7 12.8 49.9 62.3 26.4 24.5 17.2 3.0 61.6 127.5 37.3 35.3 96.8 37.9 9.8 4.4 133.9 8.4 35.2 0.0 0.2 0.0 0.2 0.0 0.0 0.3 0.2 0.0 0.0 0.6 0.0 0.1 0.2 0.6 0.0 0.0 0.0 0.0 34.4 37.0 41.6 38.1 39.1 37.2 32.7 30.7 30.5 34.3 33.8 36.9 2721.4 538.5 543.8 187.7 1018.8 1235.5 2850.5 772.6 2825.1 103.4 1647.1 2067.3 1487.5 1315.4 449.3 104.8 262.7 675.8 651.1 1653.6 50.9 987.0 49.3 1337.1 2845.2 1443.8 1497.4 174.3 12.2 516.4 93.9 2730.7 2663.1 1822.2 541.9 333.4 737.2 158.6 650.5 87.5 4.9 1909.1 836.2 584.9 632.0 48.2 1227.4 1034.9 757.7 65.6 140.1 1234.2 8.2 17.6 10.0 562.8 1529.6 258.8 1540.3 1489.1 1654.1 48.6 216.3 453.5 1538.3 1892.9 2392.5 17.4 20.9 2146.3 964.4 415.6 1065.5 846.5 1199.5 545.7 KATNBL1 "C15orf29, FLJ22557" ENSG00000134152 "Katanin regulatory subunit B1 like 1" Q9H079 15 34140674-34210096 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 128.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 128.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062573 Approved Supported "Nucleoplasm,Midbody,Cleavage furrow,Mitotic spindle" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Midbody, Mitotic spindle" "Nucleoplasm, Cleavage furrow" "HPA062573: AB_2684796" "unprognostic (5.02e-1)" "unprognostic (1.67e-1)" "unprognostic (1.35e-2)" "unprognostic (2.91e-2)" "unprognostic (2.01e-2)" "unprognostic (1.38e-1)" "unprognostic (1.14e-1)" "unprognostic (1.75e-1)" "unprognostic (1.01e-1)" "unprognostic (5.16e-2)" "unprognostic (3.94e-3)" "unprognostic (8.00e-3)" "prognostic unfavorable (4.60e-5)" "unprognostic (2.71e-2)" "unprognostic (7.23e-2)" "unprognostic (2.42e-1)" "unprognostic (1.43e-1)" 22.0 12.1 16.3 22.9 16.6 16.3 20.8 25.0 20.8 22.5 22.4 19.9 15.9 20.7 19.0 39.9 16.8 15.9 13.4 15.8 14.9 17.0 17.6 18.4 17.6 15.0 13.8 14.4 14.0 14.5 12.1 32.4 16.0 16.9 21.2 31.2 14.6 13.6 13.2 31.4 15.7 25.4 12.9 18.6 17.7 18.0 18.2 15.2 12.5 13.0 20.3 17.8 27.7 25.3 37.1 31.5 49.7 33.4 39.5 39.0 37.0 49.6 30.0 38.7 38.4 17.8 19.9 17.6 31.2 32.2 54.5 47.5 24.9 28.5 45.8 36.9 12.6 31.8 34.6 21.6 27.0 33.9 33.1 23.6 40.8 26.1 51.3 39.7 70.6 45.4 34.3 36.7 53.1 17.6 21.4 27.4 35.8 47.4 25.0 32.3 30.3 16.1 35.9 49.5 28.1 24.8 30.1 21.9 14.7 49.2 27.0 38.8 40.4 51.9 26.7 46.8 39.7 21.5 32.5 37.1 46.5 35.7 38.9 62.8 18.2 29.7 18.4 17.3 23.3 23.9 19.6 18.8 20.7 25.6 21.5 19.2 128.5 13.2 11.5 28.4 17.9 12.0 16.3 16.6 25.0 20.8 15.8 14.9 15.0 13.8 16.0 12.9 18.2 25.3 59.7 38.5 25.2 83.9 41.7 41.3 65.2 60.5 34.7 57.0 42.1 43.1 12.8 24.3 51.6 25.8 52.1 58.6 42.3 30.6 33.2 59.1 75.4 40.5 53.3 47.0 23.9 39.8 104.3 54.5 86.2 38.8 39.3 50.8 44.9 68.7 37.9 20.8 39.1 67.3 96.7 35.6 52.9 27.6 48.8 59.2 31.7 36.2 32.0 64.6 49.9 53.1 27.8 86.0 114.4 105.3 37.4 33.1 41.1 116.8 21.4 41.6 49.6 44.7 59.2 52.2 45.3 47.8 44.3 45.0 54.3 179.5 39.7 31.6 39.1 132.6 KCNB2 Kv2.2 ENSG00000182674 "Potassium voltage-gated channel subfamily B member 2" Q92953 8 72537225-72938349 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.6;lymphoid tissue: 2.3;retina: 4.6" "Group enriched" "Detected in some" 14 "Cone photoreceptor cells: 264.8;Excitatory neurons: 279.1;Inhibitory neurons: 241.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 1.4;HDLM-2: 1.4;HEK 293: 3.4;SCLC-21H: 2.7" "Low region specificity" "Detected in many" HPA065970 Approved "Nucleoli,Plasma membrane,Midbody" Yes NA "Cluster 58: Brain - Synaptic function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nucleoli, Midbody" "HPA065970: AB_2685591" "unprognostic (9.87e-3)" "unprognostic (1.71e-1)" "unprognostic (7.57e-2)" "unprognostic (1.10e-3)" "unprognostic (1.22e-1)" "unprognostic (1.34e-1)" "unprognostic (1.44e-2)" "unprognostic (2.72e-1)" "unprognostic (6.93e-5)" "unprognostic (5.53e-3)" "unprognostic (3.30e-2)" "unprognostic (1.62e-1)" "unprognostic (3.35e-2)" "unprognostic (3.26e-1)" 0.1 0.4 1.7 0.0 2.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 2.4 2.2 0.0 0.0 0.0 0.0 1.0 2.6 0.0 0.5 0.0 1.1 0.0 0.4 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.3 0.0 1.3 2.3 0.4 0.3 1.5 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.4 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.0 0.0 1.4 2.4 2.2 1.0 2.6 0.4 1.3 1.5 0.0 0.1 0.0 0.0 4.6 0.0 0.0 0.0 0.0 1.2 17.4 0.0 0.0 0.3 0.0 0.0 1.8 264.8 0.0 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.1 17.9 0.0 279.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 241.2 0.6 0.0 0.0 0.0 6.8 1.2 0.0 0.0 3.7 0.0 0.7 0.0 11.6 4.7 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 4.0 0.0 0.1 0.1 0.4 1.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 KCND1 Kv4.1 ENSG00000102057 "Potassium voltage-gated channel subfamily D member 1" Q9NSA2 X 48961378-48971844 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 3.5;Peritubular cells: 3.8;Rod photoreceptor cells: 3.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 10.6;NB-4: 9.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000524, HPA001066" Supported Uncertain Nucleoplasm Yes No "Cluster 1: Neutrophils - Mixed function" "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA000524: AB_2666013, HPA001066: AB_1079662" "unprognostic (6.00e-2)" "unprognostic (2.58e-1)" "unprognostic (1.01e-4)" "unprognostic (2.19e-4)" "unprognostic (1.41e-1)" "unprognostic (3.79e-2)" "unprognostic (2.79e-1)" "unprognostic (8.13e-3)" "unprognostic (1.13e-2)" "unprognostic (2.41e-3)" "prognostic favorable (2.66e-6)" "unprognostic (2.61e-1)" "unprognostic (4.30e-11)" "unprognostic (3.13e-2)" "unprognostic (3.49e-1)" "unprognostic (7.64e-2)" "unprognostic (2.22e-3)" 3.8 0.9 2.8 1.5 2.8 2.7 1.8 5.5 2.7 2.7 0.1 2.0 0.8 3.6 1.4 1.1 5.4 2.4 2.3 2.9 3.0 1.7 1.4 2.6 1.3 3.6 2.9 2.7 1.1 0.4 2.3 1.0 3.9 2.3 0.8 6.1 0.9 2.1 0.5 1.3 2.2 2.5 3.3 3.3 1.8 1.5 3.2 0.7 1.8 0.4 1.4 2.3 2.3 3.8 0.3 1.6 0.7 3.9 5.1 4.1 1.3 0.8 3.3 2.3 1.5 1.1 0.5 1.3 2.8 2.6 0.6 0.5 0.6 0.3 2.2 2.3 2.7 1.2 1.8 0.1 1.9 0.3 2.5 10.6 1.4 4.2 0.4 3.7 0.8 1.9 0.9 3.0 1.7 3.1 0.4 9.2 2.1 0.2 0.6 1.1 0.7 1.3 2.6 1.3 0.4 1.8 0.7 0.0 1.8 7.9 1.7 1.3 2.0 0.5 2.1 0.5 0.2 2.5 3.5 3.2 1.4 3.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 2.8 2.8 5.5 2.7 2.9 3.0 3.6 2.9 3.9 3.3 3.2 3.8 0.9 0.0 1.1 1.0 0.4 0.8 0.0 0.4 0.0 0.2 0.3 0.3 0.8 0.0 0.2 1.8 0.0 0.1 0.4 0.3 1.9 0.2 0.1 0.2 1.0 0.6 3.5 0.0 0.7 0.0 0.1 1.2 0.5 0.5 0.0 1.7 1.1 0.0 0.1 0.0 1.1 0.3 0.0 0.6 0.0 0.2 1.8 0.4 0.0 1.0 0.1 0.4 0.0 2.0 0.1 0.1 0.0 3.8 0.1 0.2 0.2 0.1 0.3 3.0 0.0 0.1 0.6 0.6 0.0 0.1 0.0 0.1 0.2 0.1 0.2 0.2 KCNN1 "hSK1, KCa2.1" ENSG00000105642 "Potassium calcium-activated channel subfamily N member 1" Q92952 19 17951293-18000080 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Transport" "Calmodulin-binding, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 41 "brain: 92.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 12.8;Langerhans cells: 19.8;Skeletal myocytes: 6.8" "Cancer enhanced" "Detected in some" "testis cancer: 3.5" "Group enriched" "Detected in many" 7 "amygdala: 34.8;basal ganglia: 30.6;cerebral cortex: 67.2;hippocampal formation: 92.2;white matter: 30.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "REH: 155.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065938 Approved "Actin filaments,Cytosol" Yes No "Cluster 10: Brain - Neuronal signaling" "Cluster 14: REH - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Actin filaments, Cytosol" "HPA065938: AB_2685582" "unprognostic (7.55e-2)" "unprognostic (4.03e-2)" "unprognostic (1.82e-1)" "unprognostic (7.80e-2)" "unprognostic (1.90e-1)" "unprognostic (8.94e-5)" "unprognostic (3.92e-3)" "unprognostic (1.01e-1)" "unprognostic (8.42e-2)" "unprognostic (3.59e-1)" "unprognostic (2.71e-3)" "unprognostic (3.38e-1)" "unprognostic (5.21e-3)" "unprognostic (2.70e-2)" "unprognostic (1.14e-1)" "unprognostic (7.24e-3)" "unprognostic (3.24e-1)" 0.3 0.2 34.8 0.4 30.6 0.1 0.2 0.0 67.2 0.9 0.0 0.3 0.1 0.6 0.1 0.2 0.1 0.1 1.1 92.2 0.0 0.2 0.0 0.1 0.1 4.4 0.0 1.8 0.1 1.6 1.0 0.0 6.8 0.6 0.0 0.8 0.4 0.2 0.1 0.1 0.2 0.0 0.0 0.1 0.2 2.2 0.0 0.1 0.1 0.0 0.1 0.1 0.2 30.6 0.1 0.6 0.2 6.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.6 0.0 0.5 0.2 5.3 0.0 0.2 0.2 2.5 5.0 0.3 0.1 0.0 0.0 12.8 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.3 0.2 0.0 0.4 0.0 0.0 1.8 0.0 0.1 155.3 0.0 0.2 0.0 0.0 0.2 8.6 0.0 0.0 0.1 0.4 0.3 0.2 0.1 0.0 4.7 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.8 30.6 0.0 67.2 92.2 0.0 4.4 0.0 6.8 0.0 0.0 30.6 0.4 0.0 0.0 3.6 1.1 2.5 3.7 0.0 0.0 2.3 0.2 0.3 0.8 0.0 0.7 0.0 2.1 0.1 1.5 0.2 0.0 0.0 0.2 1.3 1.5 1.9 0.0 0.0 12.8 0.0 0.2 2.6 0.0 1.9 0.0 3.6 0.4 0.2 0.1 0.0 4.4 0.0 0.0 0.3 19.8 0.4 0.9 2.1 5.4 1.9 2.2 1.4 1.0 3.0 0.7 0.2 0.0 1.9 0.7 2.8 0.0 0.2 0.0 1.0 0.0 6.8 1.8 0.6 4.0 0.0 3.8 0.1 1.5 2.2 0.0 1.8 KCNV1 Kv8.1 ENSG00000164794 "Potassium voltage-gated channel modifier subfamily V member 1" Q6PIU1 8 109963636-109975771 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "brain: 4.9" "Group enriched" "Detected in some" 6 "Enteroendocrine cells: 7.1;Excitatory neurons: 28.2" "Cancer enhanced" "Detected in single" "renal cancer: 0.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 36.6" HPA067233 Supported "Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytokinetic bridge" "HPA067233: " "unprognostic (1.41e-1)" "unprognostic (1.81e-2)" "unprognostic (5.01e-4)" "unprognostic (2.30e-1)" "unprognostic (3.76e-2)" "unprognostic (1.13e-2)" "unprognostic (3.89e-2)" "unprognostic (2.27e-1)" "unprognostic (4.17e-2)" 0.1 0.1 1.9 0.1 4.9 0.5 0.1 0.0 4.6 0.0 0.0 0.5 0.1 0.1 0.5 0.1 0.1 0.1 0.1 3.3 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.3 0.4 0.1 0.3 0.2 0.0 0.2 0.4 0.7 0.2 0.1 0.1 0.4 0.3 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.3 0.0 0.1 0.0 0.0 1.1 0.5 0.6 0.4 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.4 0.5 0.1 0.0 0.1 0.2 0.1 0.3 0.6 0.1 0.0 0.2 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.6 0.0 0.1 0.2 0.2 0.2 0.1 0.2 0.0 0.2 0.0 0.8 0.2 0.3 0.1 0.1 0.0 0.1 0.4 0.2 0.0 0.2 0.5 0.4 0.3 0.1 0.2 0.1 0.1 0.2 0.1 0.2 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.9 4.9 0.0 4.6 3.3 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.0 7.1 0.0 28.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.8 0.0 0.0 0.0 1.5 1.7 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.3 0.0 KCTD1 C18orf5 ENSG00000134504 "Potassium channel tetramerization domain containing 1" Q719H9 18 26454910-26657401 "Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 106.4;Distal tubular cells: 117.4;Excitatory neurons: 283.7;Squamous epithelial cells: 109.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 106.6;HaCaT: 113.5;hTCEpi: 100.6;RPTEC TERT1: 97.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057808, HPA062486" Approved "Nucleoplasm,Nucleoli,Cytokinetic bridge,Centriolar satellite" Yes NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Nucleoli, Cytokinetic bridge, Centriolar satellite" "HPA057808: , HPA062486: " "unprognostic (1.15e-3)" "unprognostic (5.66e-2)" "unprognostic (2.35e-4)" "prognostic unfavorable (2.22e-4)" "unprognostic (3.65e-3)" "unprognostic (7.43e-2)" "unprognostic (2.03e-3)" "unprognostic (6.77e-2)" "unprognostic (2.74e-1)" "unprognostic (1.88e-3)" "unprognostic (5.68e-3)" "unprognostic (1.77e-2)" "prognostic favorable (4.60e-8)" "unprognostic (3.87e-3)" "unprognostic (7.39e-2)" "unprognostic (1.50e-1)" "unprognostic (8.02e-2)" 7.8 16.5 21.7 2.7 41.5 0.6 32.4 14.0 44.3 19.2 9.5 9.7 4.1 14.2 22.6 50.6 50.2 8.4 23.8 31.2 10.3 28.8 3.5 5.5 2.7 9.8 13.6 15.1 7.4 12.0 10.8 11.4 9.2 21.6 10.6 18.4 19.9 22.6 5.1 61.1 3.7 12.5 10.2 3.9 10.3 5.9 13.7 17.6 19.9 6.9 14.3 13.0 36.9 29.6 17.5 55.1 106.6 11.6 61.8 9.7 13.4 14.3 21.5 22.0 21.9 5.1 19.1 2.9 52.2 30.5 18.0 113.5 20.5 30.6 20.6 2.2 8.7 3.1 10.2 8.2 11.1 1.7 4.7 16.7 100.6 6.2 41.4 28.0 21.0 24.1 1.3 1.2 16.0 24.5 16.3 5.2 10.5 57.1 27.1 8.5 5.7 2.3 97.8 25.2 10.3 40.5 20.7 27.5 8.7 61.3 24.1 4.0 11.7 24.4 6.8 4.8 15.0 4.8 4.1 0.4 8.7 11.0 36.8 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 41.5 14.0 44.3 31.2 10.3 9.8 13.6 9.2 10.2 13.7 29.6 3.0 3.2 4.1 80.0 0.7 31.7 55.9 17.2 106.4 5.0 27.3 29.7 13.9 8.6 15.0 25.8 8.4 45.5 0.8 6.2 117.4 8.3 28.0 47.0 7.8 2.9 1.2 0.8 283.7 3.6 7.6 5.5 7.1 42.4 0.0 66.3 2.5 1.7 4.4 21.9 66.1 4.3 20.3 0.8 1.7 12.0 5.3 1.2 23.2 16.9 0.4 21.4 1.0 81.4 42.1 11.8 2.4 3.0 6.6 36.4 0.4 10.7 29.3 5.9 0.0 2.7 6.2 1.8 5.1 109.0 44.5 33.2 1.0 6.3 4.0 51.2 KDM7A "JHDM1D, KIAA1718" ENSG00000006459 "Lysine demethylase 7A" Q6ZMT4 7 140084746-140176983 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 96.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012114 Uncertain Approved Nucleoplasm,Nucleoli Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm Nucleoli "HPA012114: AB_1852429" "unprognostic (1.55e-1)" "unprognostic (1.44e-1)" "unprognostic (2.54e-1)" "unprognostic (4.08e-3)" "unprognostic (3.52e-1)" "unprognostic (1.69e-2)" "unprognostic (4.00e-1)" "unprognostic (3.44e-2)" "unprognostic (2.56e-1)" "unprognostic (3.84e-2)" "unprognostic (9.74e-2)" "unprognostic (1.29e-1)" "unprognostic (9.55e-2)" "unprognostic (3.42e-1)" "unprognostic (2.59e-1)" "unprognostic (2.10e-1)" "unprognostic (1.18e-1)" 6.6 2.1 2.1 6.9 1.6 16.4 4.7 3.8 3.9 9.5 1.5 8.4 8.2 6.6 1.4 7.0 2.9 4.5 4.1 2.7 1.6 3.6 6.7 4.8 7.0 2.5 2.5 2.1 4.5 4.1 1.3 9.1 2.8 3.3 9.3 5.8 5.1 2.1 12.6 7.5 8.3 4.4 2.4 5.6 9.3 7.7 3.7 6.7 2.8 13.2 8.0 5.7 3.7 3.0 0.8 0.4 2.7 2.8 2.4 2.3 5.4 1.2 1.7 0.4 0.5 0.2 0.4 1.9 1.9 1.3 1.4 1.0 3.7 2.3 0.8 10.8 2.3 0.1 0.4 5.1 2.5 1.8 1.9 2.4 5.1 1.4 8.0 1.3 2.6 5.0 6.1 8.2 0.5 0.8 3.6 3.1 4.3 6.3 1.5 3.8 0.2 4.0 0.9 1.2 4.7 5.8 2.8 6.5 2.7 4.3 8.8 0.7 4.6 0.5 1.0 1.7 0.8 2.9 0.4 6.2 1.5 5.0 1.0 0.6 0.8 0.3 0.3 0.4 0.3 0.5 0.5 0.5 1.1 1.1 0.5 0.3 2.2 0.6 0.2 0.4 0.4 0.3 2.1 1.6 3.8 3.9 2.7 1.6 2.5 2.5 2.8 2.4 3.7 3.0 34.4 16.0 25.5 25.5 30.6 49.8 44.8 17.7 8.0 11.8 11.1 7.4 14.6 8.6 30.1 16.5 27.1 12.3 17.8 36.7 1.9 7.2 5.2 17.0 18.2 23.8 52.7 32.4 35.3 9.4 2.8 20.0 30.5 28.7 8.2 12.2 18.5 18.5 10.7 6.7 34.8 38.0 12.2 31.4 86.7 4.9 7.8 35.4 3.6 96.5 34.7 4.3 10.3 35.7 36.0 12.2 28.7 4.1 11.8 35.3 26.9 3.3 33.3 9.2 6.6 14.9 17.8 31.2 14.3 12.3 46.5 37.9 18.5 3.4 27.2 50.0 KIAA1143 ENSG00000163807 KIAA1143 Q96AT1 3 44737661-44761619 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 245.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045018, HPA061799" Approved Enhanced "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 49: Eosinophils - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 32: U-937 - Innate immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "Cytokinetic bridge" "HPA045018: AB_10964578, HPA061799: AB_2684614" "unprognostic (1.31e-1)" "unprognostic (2.74e-1)" "prognostic favorable (3.65e-4)" "unprognostic (2.25e-1)" "unprognostic (6.00e-2)" "unprognostic (3.01e-3)" "unprognostic (2.23e-3)" "unprognostic (6.17e-2)" "unprognostic (6.42e-2)" "unprognostic (1.57e-3)" "unprognostic (3.71e-1)" "unprognostic (4.08e-2)" "prognostic favorable (3.26e-6)" "unprognostic (1.82e-1)" "unprognostic (1.85e-1)" "unprognostic (3.19e-2)" "unprognostic (6.46e-2)" 9.2 7.4 3.6 4.9 4.5 4.4 8.2 3.9 4.7 7.7 2.1 8.9 4.5 10.4 3.5 6.5 7.8 5.4 9.8 3.4 4.0 7.0 4.9 5.7 6.4 4.4 4.3 11.0 7.5 8.1 4.7 6.4 4.4 9.0 5.1 5.8 7.0 6.2 17.4 7.0 6.5 7.4 3.7 6.4 7.0 3.1 4.1 9.2 8.4 9.0 7.2 8.1 6.5 6.0 8.3 5.3 14.7 10.2 9.8 15.1 7.3 9.3 13.1 11.7 11.9 5.3 7.2 20.2 6.9 9.8 5.6 5.6 17.5 9.9 15.4 11.2 5.9 14.7 9.6 6.5 6.7 18.6 9.9 10.9 11.7 12.0 11.3 13.0 9.9 12.3 21.2 10.8 11.6 4.7 20.9 13.1 13.9 8.7 6.8 8.5 14.0 11.5 7.5 7.0 7.3 12.5 10.9 8.3 7.5 9.8 13.9 15.8 11.5 6.5 5.8 17.2 10.7 6.9 21.1 12.1 12.0 17.8 9.7 2.6 2.3 4.0 2.8 2.5 2.4 2.5 2.4 2.2 2.2 2.3 2.5 2.4 2.3 3.1 3.8 1.5 2.1 1.9 3.6 4.5 3.9 4.7 3.4 4.0 4.4 4.3 4.4 3.7 4.1 6.0 35.8 38.5 39.4 5.9 32.9 34.5 31.6 44.1 25.0 20.0 24.5 24.0 28.4 32.9 43.6 23.9 8.4 40.6 32.5 18.8 68.4 45.5 245.7 29.0 32.4 34.6 15.6 27.3 5.4 62.6 55.8 28.9 18.3 29.3 38.6 17.6 37.1 26.4 35.0 15.2 6.0 24.6 26.4 42.9 27.3 84.4 37.6 30.3 14.2 5.6 37.7 44.8 41.2 5.5 10.1 48.9 24.0 49.2 19.1 51.0 23.5 45.2 30.5 14.0 0.0 43.3 28.3 53.8 40.5 22.3 27.8 57.2 35.3 25.7 25.7 46.7 KIF11 "Eg5, HKSP, KNSL1, TRIP5" ENSG00000138160 "Kinesin family member 11" P52732 10 92574105-92655395 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.4;lymphoid tissue: 37.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 39.1;Granulosa cells: 20.7;Spermatocytes: 38.0;Spermatogonia: 23.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA006916, HPA010093, HPA010568, CAB017617" Enhanced Supported "Mitotic spindle,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Mitotic spindle" "CAB017617: AB_2131098, HPA006916: AB_1848033, HPA010093: AB_2668281, HPA010568: AB_1848034" "unprognostic (1.53e-1)" "unprognostic (1.11e-2)" "unprognostic (1.59e-2)" "unprognostic (3.35e-2)" "unprognostic (2.12e-1)" "unprognostic (7.82e-2)" "prognostic unfavorable (8.19e-7)" "prognostic unfavorable (3.27e-4)" "unprognostic (1.24e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.30e-4)" "unprognostic (6.59e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.35e-3)" "unprognostic (7.23e-2)" "unprognostic (9.08e-2)" "unprognostic (2.01e-1)" 1.1 0.7 0.5 8.5 0.7 19.4 2.5 0.4 0.6 1.4 0.5 6.3 5.5 1.8 1.0 6.7 1.0 1.2 0.6 0.5 0.5 1.0 1.1 1.3 17.5 0.6 0.6 0.6 0.5 0.7 0.3 3.9 0.6 1.0 7.4 0.8 1.3 0.7 0.2 6.0 5.3 2.5 0.5 2.9 3.9 11.6 0.4 37.9 1.6 0.3 18.5 2.3 2.3 0.6 103.1 45.2 100.6 94.5 7.3 10.5 24.2 72.6 62.8 78.8 78.1 39.6 67.2 111.1 36.5 34.4 32.9 72.0 72.1 36.5 92.4 68.3 41.3 70.5 41.4 42.4 1.4 116.0 63.0 3.6 3.3 61.4 55.9 18.3 50.0 46.1 51.2 126.4 61.1 41.4 99.3 65.8 40.3 42.5 30.7 106.6 98.8 40.2 21.0 30.1 30.0 42.9 56.4 25.9 29.2 34.1 67.9 37.6 28.6 35.7 51.3 37.1 96.9 35.4 58.3 113.4 29.5 82.3 50.3 0.8 0.0 0.1 0.0 0.3 0.3 0.6 0.4 0.4 0.2 0.1 0.1 0.2 0.2 1.0 0.1 0.1 1.1 0.2 0.5 0.7 0.4 0.6 0.5 0.5 0.6 0.6 0.6 0.5 0.4 0.6 0.4 0.0 2.0 1.3 3.5 2.9 1.1 1.6 3.4 1.0 1.8 1.8 1.7 1.5 2.5 1.8 0.0 6.7 2.3 2.9 1.9 0.5 16.3 3.4 4.3 2.0 0.0 39.1 2.1 0.6 11.4 4.7 9.2 4.9 0.0 20.7 2.2 0.4 8.2 0.0 1.8 4.3 4.1 4.6 3.4 4.4 0.9 4.0 0.0 0.0 1.0 0.7 2.1 2.5 1.1 0.2 0.4 0.7 15.2 0.8 0.5 0.6 3.7 0.4 0.0 1.7 3.7 38.0 23.4 12.6 3.3 1.5 4.5 2.5 8.0 1.7 KIF14 KIAA0042 ENSG00000118193 "Kinesin family member 14" Q15058 1 200551497-200620751 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Ciliopathy, Disease variant, Meckel syndrome, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.5;lymphoid tissue: 10.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 27.1;Granulosa cells: 13.2;Spermatocytes: 22.8;Spermatogonia: 16.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038061, HPA058220" Uncertain Supported "Midbody ring,Cytosol" Yes Yes "Cluster 18: Basophils - Vesicular transport" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Midbody ring" "HPA038061: AB_10669515, HPA058220: AB_2683642" "unprognostic (1.84e-1)" "unprognostic (7.15e-2)" "unprognostic (2.00e-2)" "unprognostic (1.87e-2)" "unprognostic (2.74e-1)" "unprognostic (1.51e-1)" "unprognostic (1.18e-3)" "prognostic unfavorable (8.64e-4)" "unprognostic (8.47e-3)" "unprognostic (1.02e-1)" "unprognostic (2.54e-5)" "unprognostic (2.31e-2)" "unprognostic (0.00e+0)" "unprognostic (6.28e-3)" "unprognostic (3.31e-1)" "unprognostic (8.14e-2)" "unprognostic (7.44e-2)" 0.2 0.2 0.1 2.0 0.0 6.5 0.3 0.2 0.3 0.2 0.1 0.9 1.2 0.3 0.0 1.0 0.0 0.2 0.0 0.1 0.1 0.0 0.3 0.2 3.2 0.1 0.2 0.0 0.0 0.0 0.0 0.9 0.1 0.0 1.2 0.1 0.1 0.0 0.0 1.0 1.1 0.6 0.0 0.6 0.6 2.5 0.1 10.9 0.1 0.0 3.2 0.4 0.3 0.1 29.7 17.3 26.8 15.0 0.8 3.0 14.8 20.0 11.7 18.7 16.8 10.5 15.1 18.0 7.0 9.6 11.6 23.0 21.6 13.3 26.7 22.1 11.3 28.8 24.8 10.3 0.1 45.5 15.7 0.6 0.6 20.9 17.8 4.0 13.5 26.3 44.0 22.6 23.5 12.1 26.9 14.2 22.6 8.7 15.0 24.3 35.4 22.8 6.3 8.3 12.7 14.0 28.3 9.5 11.0 19.8 12.9 11.6 11.1 14.7 17.3 16.2 35.3 8.2 8.9 25.8 8.6 24.0 30.5 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.3 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 1.0 0.0 0.0 0.0 1.9 2.4 1.0 1.1 0.6 2.3 1.5 1.9 0.8 0.0 0.9 0.0 2.1 4.2 0.6 2.5 0.0 0.2 4.1 3.7 2.2 1.6 0.0 27.1 1.1 0.0 7.7 3.3 10.2 5.0 2.5 13.2 2.5 0.9 5.4 0.0 0.9 5.2 0.0 2.9 1.9 2.5 0.6 2.3 0.0 0.0 0.4 0.5 0.0 0.5 0.8 0.3 0.0 0.7 11.3 1.2 0.2 0.1 1.4 0.8 6.6 1.4 2.1 22.8 16.3 8.3 0.9 1.4 2.3 0.7 4.3 1.9 KIF18A "DKFZP434G2226, PPP1R99" ENSG00000121621 "Kinesin family member 18A" Q8NI77 11 28020619-28108156 "Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 8.2;lymphoid tissue: 9.6;testis: 13.7" "Cell type enhanced" "Detected in many" "Early spermatids: 43.1;Spermatocytes: 78.7;Spermatogonia: 28.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 4.1;memory B-cell: 1.0;NK-cell: 1.4;T-reg: 1.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA039312, HPA039484" Approved Supported "Microtubules,Cytokinetic bridge" Yes Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Microtubules, Cytokinetic bridge" "HPA039312: AB_10794087, HPA039484: AB_10795252" "unprognostic (3.79e-1)" "unprognostic (2.63e-1)" "unprognostic (7.09e-3)" "unprognostic (3.80e-2)" "unprognostic (6.56e-2)" "unprognostic (1.39e-1)" "unprognostic (1.34e-7)" "unprognostic (2.43e-3)" "unprognostic (2.04e-3)" "unprognostic (1.23e-2)" "unprognostic (1.72e-4)" "unprognostic (4.41e-2)" "unprognostic (0.00e+0)" "unprognostic (7.88e-3)" "unprognostic (1.67e-1)" "unprognostic (1.43e-1)" "unprognostic (2.50e-1)" 0.2 0.1 0.0 1.9 0.1 8.2 0.7 0.0 0.1 0.7 0.1 1.6 1.5 0.5 0.3 1.4 0.3 0.5 0.0 0.1 0.1 0.3 0.3 1.0 4.7 0.1 0.1 0.1 0.1 0.1 0.1 1.5 0.1 0.3 2.0 0.6 0.3 0.4 0.2 1.2 1.4 0.8 0.1 0.7 0.6 13.7 0.2 9.6 1.1 0.1 4.6 0.7 0.5 0.1 27.9 27.4 27.2 19.0 0.9 3.7 9.1 28.3 13.2 44.2 46.0 9.2 11.0 23.3 10.0 14.7 24.1 27.2 23.4 11.1 61.4 23.4 14.2 15.2 17.8 11.8 2.1 22.6 13.4 6.8 1.4 15.5 18.1 7.8 17.2 19.0 24.6 20.0 25.2 14.8 23.1 16.7 13.4 18.0 11.1 17.8 65.0 11.6 12.5 8.0 16.3 12.6 23.7 11.1 7.8 16.5 23.8 6.9 10.1 35.0 27.2 33.2 37.4 7.9 19.8 23.4 21.0 16.5 25.2 4.1 0.0 0.3 0.1 0.2 0.3 1.0 0.4 0.2 0.3 0.4 0.3 0.1 0.0 1.4 0.0 0.3 1.1 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 1.2 3.2 0.0 0.0 4.7 2.3 1.3 1.4 1.2 0.3 1.3 2.9 0.5 0.0 2.2 0.0 6.2 4.6 2.8 1.9 0.0 0.6 43.1 3.4 2.5 1.1 1.8 15.4 0.2 0.9 7.1 5.4 1.5 3.4 4.5 9.7 1.4 0.0 2.2 0.0 0.1 1.9 0.0 1.6 1.4 8.7 0.6 1.4 0.0 1.0 1.1 0.7 1.0 0.5 0.9 0.5 0.1 0.4 5.1 0.2 0.2 0.6 1.7 1.9 0.0 2.5 1.9 78.7 28.3 4.3 1.0 1.6 3.9 2.7 3.6 0.5 KIF18B ENSG00000186185 "Kinesin family member 18B" Q86Y91 17 44924709-44947773 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 12.7;lymphoid tissue: 14.4" "Cell type enhanced" "Detected in some" "Erythroid cells: 9.0;Extravillous trophoblasts: 3.8;Granulosa cells: 5.9;Oligodendrocyte precursor cells: 7.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in single" "white matter: 1.4" "Low region specificity" "Detected in many" HPA024205 Enhanced Supported "Nucleoplasm,Nuclear bodies,Microtubule ends,Cytosol" Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Microtubule ends" "Nuclear bodies, Cytosol" "HPA024205: AB_1852472" "unprognostic (1.88e-1)" "unprognostic (9.92e-2)" "unprognostic (4.61e-2)" "unprognostic (1.13e-2)" "unprognostic (4.17e-1)" "unprognostic (7.27e-3)" "prognostic unfavorable (2.44e-6)" "unprognostic (3.34e-3)" "prognostic unfavorable (6.90e-4)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.16e-4)" "unprognostic (8.18e-2)" "unprognostic (0.00e+0)" "unprognostic (4.69e-3)" "unprognostic (1.93e-1)" "unprognostic (3.08e-1)" "unprognostic (1.68e-2)" 0.4 0.4 0.3 3.8 0.4 12.7 0.2 0.7 0.3 0.9 0.3 2.0 2.7 0.4 0.0 5.1 0.2 0.4 0.3 0.3 0.4 0.2 0.4 0.8 5.7 0.5 1.1 0.1 0.1 0.0 0.1 1.9 0.6 0.2 1.7 0.1 0.7 0.0 0.4 3.0 2.5 1.1 0.3 2.9 1.5 2.9 0.6 14.4 0.2 0.0 4.7 0.6 1.6 0.5 31.5 41.7 35.3 32.8 0.8 3.0 28.1 25.8 10.3 34.6 26.9 34.0 27.4 28.3 10.9 10.8 21.5 34.0 25.1 11.3 17.9 56.6 36.4 35.4 51.7 22.1 0.0 30.0 30.2 0.7 0.6 29.7 12.2 4.7 17.9 29.2 28.1 48.0 18.2 25.9 60.0 31.1 25.4 30.4 28.9 43.5 51.8 19.2 5.8 16.7 26.2 24.7 18.0 16.1 9.8 17.0 30.2 21.6 11.2 49.9 48.0 28.8 56.8 15.1 15.7 34.4 16.3 22.9 33.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.3 0.4 0.7 0.3 0.3 0.4 0.5 1.1 0.6 0.3 0.6 0.5 0.1 0.0 0.0 0.0 0.9 0.4 0.1 0.2 0.0 0.5 0.5 0.4 2.6 0.0 0.0 0.0 0.0 2.4 0.4 1.9 0.0 0.0 0.0 0.3 0.8 0.6 0.0 9.0 0.3 0.0 3.8 1.4 1.5 0.5 0.0 5.9 0.4 0.3 2.3 0.0 0.3 1.6 0.0 2.2 1.1 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 7.1 0.1 0.1 0.0 0.0 2.1 0.2 0.3 0.0 0.0 0.3 0.0 0.2 0.8 1.1 2.9 2.5 0.4 0.8 1.3 0.3 3.2 0.3 KIF20A RAB6KIFL ENSG00000112984 "Kinesin family member 20A" O95235 5 138178719-138187723 "Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.1;lymphoid tissue: 24.6;testis: 11.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 11.0;Erythroid cells: 24.6;Extravillous trophoblasts: 13.1;Granulosa cells: 11.1;Spermatocytes: 21.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "NK-cell: 6.6;T-reg: 2.5" "Group enriched" "Detected in many" 46 "NK-cells: 6.6;T-cells: 2.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA036909, HPA036910" Approved Uncertain "Nucleoplasm,Cytokinetic bridge" Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytokinetic bridge" "HPA036909: AB_10670245, HPA036910: AB_10671716" "unprognostic (7.50e-2)" "unprognostic (2.43e-1)" "unprognostic (1.39e-3)" "unprognostic (1.21e-2)" "unprognostic (3.47e-2)" "unprognostic (2.60e-2)" "prognostic unfavorable (2.14e-12)" "prognostic unfavorable (6.79e-4)" "unprognostic (2.86e-2)" "unprognostic (3.16e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (9.73e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (9.05e-2)" "unprognostic (2.61e-1)" "unprognostic (1.09e-1)" "unprognostic (3.16e-1)" 0.7 0.8 0.0 4.5 0.1 14.1 1.3 0.1 0.1 1.0 0.1 3.3 3.5 1.4 0.0 6.6 0.4 0.8 0.5 0.0 0.1 0.4 0.9 0.9 8.6 0.1 0.2 0.2 0.2 0.1 0.0 5.4 0.1 0.2 5.1 0.0 1.0 0.1 0.1 4.4 2.8 5.8 0.0 1.9 2.1 11.7 0.5 24.6 0.5 0.1 13.1 1.6 2.0 0.1 87.8 59.5 127.8 84.4 6.7 12.3 53.9 75.0 68.9 162.3 121.4 111.9 80.5 38.8 39.2 96.5 60.6 85.9 121.7 142.5 160.9 56.4 57.4 57.2 101.1 70.7 0.3 28.2 25.1 4.8 2.3 86.2 49.5 27.1 106.7 53.9 24.4 70.4 113.9 81.5 47.6 26.7 80.6 51.8 63.7 51.2 128.5 39.5 43.9 42.3 37.8 37.5 144.1 47.9 30.9 161.6 60.8 28.5 51.1 41.6 60.5 38.0 126.4 36.0 37.5 42.0 26.7 81.1 82.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 2.5 0.3 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.5 0.1 0.3 0.0 1.7 0.0 0.8 0.4 0.4 2.9 0.0 0.0 1.1 1.3 0.3 0.0 0.7 0.0 0.0 11.0 0.1 2.8 0.0 0.1 1.0 1.0 1.9 1.7 0.0 24.6 0.0 0.0 13.1 3.1 2.6 1.3 4.5 11.1 3.3 0.4 6.1 0.0 0.0 1.6 6.1 2.2 0.4 2.0 0.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.4 3.0 0.3 1.2 0.0 0.9 0.0 0.0 0.5 4.4 21.7 7.5 5.3 0.4 1.0 0.7 0.8 3.4 0.6 KIF20B "CT90, KRMP1, MPHOSPH1, MPP1" ENSG00000138182 "Kinesin family member 20B" Q96Q89 10 89701590-89774939 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.2;lymphoid tissue: 9.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 89.2;Spermatocytes: 165.4;Spermatogonia: 96.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA050214 Supported Supported "Nucleoplasm,Cytokinetic bridge,Midbody,Cytosol" Yes Yes "Cluster 6: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytokinetic bridge" "Midbody, Cytosol" "HPA050214: AB_2681053" "unprognostic (2.13e-1)" "unprognostic (3.01e-2)" "unprognostic (1.72e-2)" "unprognostic (3.20e-2)" "unprognostic (2.65e-1)" "unprognostic (7.39e-2)" "unprognostic (8.95e-5)" "unprognostic (3.32e-3)" "unprognostic (2.01e-2)" "unprognostic (8.14e-2)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.62e-2)" "prognostic unfavorable (3.06e-6)" "unprognostic (4.22e-3)" "unprognostic (2.70e-1)" "unprognostic (2.51e-2)" "unprognostic (6.43e-2)" 1.3 0.7 0.3 4.5 1.0 10.2 2.5 2.4 0.4 1.5 0.1 3.2 3.6 2.3 0.4 3.3 1.2 1.3 0.9 0.3 0.3 1.3 1.3 1.5 8.0 0.5 0.3 2.7 0.7 1.1 0.2 2.4 0.6 1.3 4.0 1.1 1.0 0.9 0.4 2.5 3.4 2.2 0.4 3.3 2.5 6.9 0.6 9.8 1.8 0.7 7.5 1.6 0.7 0.6 84.8 17.0 24.3 21.7 4.7 8.0 20.2 33.8 30.9 34.8 36.3 22.6 38.1 32.5 10.4 17.3 13.0 41.8 27.3 18.9 46.4 39.5 18.6 33.1 30.5 19.5 1.4 57.1 26.3 3.4 2.8 33.7 33.9 12.2 22.8 17.0 32.2 36.5 31.3 14.6 33.6 10.8 25.0 13.8 16.1 23.1 47.8 14.3 10.7 11.2 7.7 13.9 24.4 11.0 12.2 17.3 28.5 16.3 17.9 22.2 22.1 29.1 55.3 10.1 29.5 43.2 21.1 49.4 16.8 13.1 2.4 4.2 5.5 4.1 6.8 13.0 7.4 6.1 1.3 16.0 8.6 8.0 0.2 3.0 4.5 5.2 9.5 2.2 0.3 1.0 2.4 0.4 0.3 0.3 0.5 0.3 0.6 0.4 0.6 0.6 11.5 3.2 13.5 2.3 36.4 17.7 6.2 20.8 6.8 14.3 8.3 8.5 8.7 1.5 10.7 0.0 10.4 21.4 32.3 8.8 3.9 6.9 13.1 10.6 13.2 11.0 1.2 89.2 8.1 4.7 38.1 13.2 14.8 12.9 44.4 37.2 9.3 4.4 20.7 13.5 9.5 8.6 16.2 21.0 17.9 10.5 8.1 17.1 5.4 23.4 11.3 7.5 24.7 9.0 9.1 4.1 5.7 8.6 51.4 3.7 8.9 3.2 6.6 9.8 6.6 16.9 17.1 165.4 96.7 26.1 14.1 5.2 34.2 12.9 25.5 5.2 KIF21B "DKFZP434J212, KIAA0449" ENSG00000116852 "Kinesin family member 21B" O75037 1 200969390-201023714 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.1;brain: 21.6;retina: 21.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 25.7;Cone photoreceptor cells: 58.4;Late spermatids: 82.1;Rod photoreceptor cells: 26.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "basophil: 6.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.0" "Cell line enhanced" "Detected in many" "Daudi: 39.1;HMC-1: 41.0;JURKAT: 78.8;Karpas-707: 49.6;RPMI-8226: 43.8;U-266/70: 90.2;U-266/84: 44.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027249, HPA027274" Approved Approved "Plasma membrane,Mitotic spindle,Cytosol" Yes No "Cluster 11: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Mitotic spindle, Cytosol" "HPA027249: AB_10602241, HPA027274: AB_1852483" "unprognostic (3.49e-2)" "unprognostic (1.82e-1)" "unprognostic (4.70e-2)" "unprognostic (2.15e-1)" "unprognostic (2.28e-1)" "unprognostic (3.92e-3)" "unprognostic (1.32e-2)" "unprognostic (1.80e-1)" "unprognostic (2.18e-1)" "unprognostic (3.03e-1)" "unprognostic (1.54e-3)" "unprognostic (7.14e-2)" "unprognostic (1.41e-4)" "unprognostic (5.98e-3)" "unprognostic (2.64e-1)" "unprognostic (6.81e-2)" "unprognostic (5.81e-4)" 1.6 0.8 16.1 9.4 16.4 34.1 1.3 0.0 16.5 0.9 0.0 2.4 2.0 0.7 0.4 0.8 1.2 2.1 0.7 21.6 8.3 0.9 1.5 4.8 12.9 5.9 5.7 0.7 0.8 6.0 0.6 0.9 6.5 0.8 1.8 21.4 1.4 0.7 0.3 0.7 6.7 0.8 1.5 12.3 2.5 13.7 9.5 11.8 1.0 0.4 8.0 2.3 0.8 7.9 1.3 1.5 11.8 0.5 0.0 0.0 3.0 0.1 0.0 0.3 0.1 0.7 0.4 39.1 0.5 0.0 3.4 0.3 1.2 0.3 0.4 1.9 0.4 9.7 0.2 0.2 1.0 29.4 41.0 1.0 4.1 0.4 0.7 0.0 1.5 78.8 4.6 49.6 0.0 0.2 24.5 11.2 5.2 3.9 0.0 8.4 0.1 43.8 0.2 0.0 7.2 1.0 0.6 0.5 0.6 2.1 0.2 8.9 2.8 0.0 3.3 0.0 0.2 90.2 44.7 19.3 3.9 12.8 0.3 6.0 0.0 0.6 0.8 0.2 0.9 0.4 0.6 0.8 0.1 0.3 0.5 0.6 1.0 1.3 0.3 0.1 0.6 0.4 16.1 16.4 0.0 16.5 21.6 8.3 5.9 5.7 6.5 1.5 9.5 7.9 1.5 0.0 3.8 22.5 11.0 1.0 0.5 0.2 0.0 25.7 0.4 0.8 1.5 0.0 0.1 1.8 58.4 0.0 17.4 1.2 0.0 0.5 20.4 0.1 0.2 1.8 0.0 4.8 15.6 1.6 0.1 0.6 1.1 0.4 6.3 0.5 1.4 0.3 1.7 1.7 11.8 1.4 0.0 4.4 3.1 82.1 0.9 5.3 0.0 8.4 2.7 20.0 13.4 14.6 4.0 2.4 0.3 0.0 12.0 0.4 0.2 0.0 0.1 26.1 6.6 0.6 1.1 1.9 3.7 0.1 1.0 0.0 18.0 0.1 1.1 2.0 KIF23 "KNSL5, MKLP-1, MKLP1" ENSG00000137807 "Kinesin family member 23" Q02241 15 69414246-69448427 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.6;lymphoid tissue: 15.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 24.2;Erythroid cells: 42.3;Extravillous trophoblasts: 32.4;Granulosa cells: 22.4;Spermatocytes: 70.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 4.6" "Group enriched" "Detected in many" 13 "granulocytes: 4.6;monocytes: 1.2;T-cells: 1.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB010414, HPA045208, HPA068831" Uncertain Enhanced "Nucleoplasm,Midbody ring,Mitotic spindle" Yes Yes "Cluster 49: Eosinophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Midbody ring, Mitotic spindle" "CAB010414: AB_631959, HPA045208: AB_2679254, HPA068831: AB_2686045" "unprognostic (1.29e-1)" "unprognostic (2.40e-1)" "unprognostic (5.57e-2)" "prognostic unfavorable (8.62e-4)" "unprognostic (1.86e-1)" "unprognostic (7.99e-3)" "prognostic unfavorable (3.18e-5)" "unprognostic (1.43e-3)" "unprognostic (4.25e-3)" "unprognostic (2.60e-1)" "prognostic unfavorable (3.69e-5)" "unprognostic (5.85e-3)" "unprognostic (0.00e+0)" "unprognostic (1.15e-2)" "unprognostic (2.59e-1)" "unprognostic (1.17e-1)" "unprognostic (9.17e-2)" 1.0 1.5 0.3 5.7 0.2 21.6 1.4 0.2 0.3 1.5 1.4 4.1 3.9 2.0 0.1 5.3 0.9 1.3 0.6 0.3 0.2 4.6 0.5 1.5 7.9 0.2 0.3 0.7 0.5 0.4 0.1 6.4 0.3 0.9 5.0 0.2 1.1 1.2 0.1 3.7 3.8 4.2 0.2 2.2 2.0 10.6 0.3 15.9 0.3 0.2 9.8 1.8 2.1 0.2 100.7 81.5 64.2 59.0 3.7 7.3 36.3 105.3 57.0 154.8 120.6 50.2 72.4 56.8 31.4 53.1 78.6 110.5 121.6 39.5 158.7 52.9 60.2 55.3 78.8 30.7 2.1 55.6 48.3 3.3 4.2 71.8 60.5 19.4 52.0 46.9 36.0 70.2 95.4 44.1 31.2 28.2 71.6 35.5 33.2 37.0 133.8 31.2 39.3 49.7 32.5 25.3 120.4 51.9 44.9 74.5 50.6 25.3 34.5 90.0 120.8 62.0 157.6 26.3 74.3 48.4 31.5 72.2 78.0 0.0 1.2 4.6 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.6 0.0 1.2 0.3 0.3 0.2 0.2 0.3 0.3 0.2 0.2 0.3 0.3 0.2 0.3 0.2 0.4 0.0 0.5 0.0 2.3 1.9 3.7 4.2 0.0 0.2 1.8 2.8 0.8 5.7 4.7 7.3 2.1 24.2 1.4 3.3 3.9 1.8 13.3 13.1 3.6 2.2 1.8 42.3 1.8 0.0 32.4 5.8 3.6 8.7 2.5 22.4 3.9 0.3 8.1 0.0 1.0 3.1 0.0 2.8 3.4 4.8 0.9 3.2 0.0 1.0 8.1 0.2 0.0 0.0 0.2 0.4 0.4 1.9 6.8 1.6 0.8 0.9 3.6 0.1 6.6 0.4 8.2 70.8 20.9 11.3 1.0 2.5 4.2 3.6 8.6 3.3 KIF2A "HK2, KIF2" ENSG00000068796 "Kinesin family member 2A" O00139 5 62306162-62391025 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis" "Developmental protein, Motor protein" "Cancer-related genes, Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004715, HPA004716" Approved Enhanced Nucleoplasm,Nucleoli,Centrosome Yes No 300000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Nucleoli, Centrosome" "HPA004715: AB_2667215, HPA004716: AB_1079211" "unprognostic (2.40e-2)" "unprognostic (3.43e-1)" "prognostic favorable (1.70e-4)" "unprognostic (2.74e-2)" "unprognostic (1.43e-1)" "prognostic favorable (5.45e-4)" "prognostic unfavorable (3.17e-6)" "unprognostic (8.77e-3)" "unprognostic (4.69e-2)" "unprognostic (9.10e-2)" "unprognostic (1.85e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (3.81e-5)" "unprognostic (3.53e-2)" "unprognostic (2.95e-2)" "unprognostic (1.65e-1)" "unprognostic (1.58e-1)" 11.9 7.7 15.6 23.2 20.7 12.8 10.8 15.5 17.7 19.5 0.0 13.8 11.5 12.0 6.3 12.5 17.6 12.9 6.2 17.4 23.0 8.0 5.3 9.8 32.8 17.9 17.5 12.9 10.2 12.3 8.5 16.9 18.4 9.9 14.7 42.7 6.9 11.4 4.8 5.9 15.9 13.1 14.6 18.4 9.6 49.1 16.1 43.6 12.6 6.8 28.9 20.2 7.2 28.0 47.3 46.9 81.4 67.3 28.8 39.6 65.2 51.2 38.5 54.6 67.5 53.1 49.6 111.9 53.3 41.9 67.2 29.1 61.3 37.7 72.5 116.8 44.2 113.8 41.2 27.8 34.7 65.3 42.9 30.5 26.6 50.1 47.5 33.1 49.1 66.5 86.6 66.7 46.9 36.1 104.4 33.1 42.6 12.0 31.9 78.3 59.6 65.3 25.4 55.4 68.0 55.9 67.0 27.9 34.7 55.3 37.6 38.5 39.8 31.9 52.2 40.5 51.3 64.8 94.9 114.1 36.4 74.5 39.8 10.4 4.6 4.7 29.2 5.0 35.3 13.5 29.8 32.7 6.2 10.5 26.3 29.0 7.8 23.2 3.3 9.6 42.3 17.7 15.6 20.7 15.5 17.7 17.4 23.0 17.9 17.5 18.4 14.6 16.1 28.0 30.8 16.0 14.1 54.5 44.1 16.8 41.4 20.1 39.3 45.5 17.9 23.9 9.4 4.3 20.5 20.2 104.3 20.3 73.4 23.1 13.7 37.5 113.8 103.3 47.2 21.4 21.0 42.3 56.7 30.9 22.6 28.2 20.4 43.4 17.7 25.6 19.6 4.4 15.4 52.2 64.5 7.9 14.2 12.9 22.1 130.7 13.1 83.6 12.4 26.2 104.9 28.0 76.2 119.6 156.0 26.6 26.1 13.2 47.8 42.7 13.5 18.7 49.2 92.9 26.3 33.1 25.4 118.9 42.8 34.3 9.5 43.9 77.9 48.9 11.0 56.1 KIF2B ENSG00000141200 "Kinesin family member 2B" Q8N4N8 17 53822927-53825193 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 508 "testis: 75.3" "Group enriched" "Detected in some" 68 "Early spermatids: 744.0;Late spermatids: 623.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023081, HPA023103, HPA024795" Uncertain Supported "Nucleoli,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 74: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" "Microtubules, Cytokinetic bridge, Mitotic spindle" Nucleoli "HPA023081: AB_10600082, HPA023103: AB_10611254, HPA024795: AB_10602197" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 75.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 744.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 623.2 6.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 10.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KIF2C "CT139, KNSL6, MCAK" ENSG00000142945 "Kinesin family member 2C" Q99661 1 44739818-44767767 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 33.0;lymphoid tissue: 37.4;testis: 76.5" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1860.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 2.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in some" "white matter: 2.1" "Not detected" "Not detected" "HPA006219, HPA079172" Enhanced Supported Nucleoplasm,Midbody,Centrosome Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Centrosome" Midbody "HPA006219: AB_2667540, HPA079172: " "unprognostic (3.29e-2)" "unprognostic (1.35e-2)" "unprognostic (1.03e-2)" "unprognostic (1.71e-3)" "unprognostic (2.77e-1)" "unprognostic (5.17e-2)" "prognostic unfavorable (3.07e-7)" "unprognostic (7.49e-3)" "unprognostic (3.33e-3)" "unprognostic (3.66e-1)" "prognostic unfavorable (6.86e-4)" "unprognostic (4.27e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.33e-3)" "unprognostic (1.49e-1)" "unprognostic (1.86e-2)" "unprognostic (2.41e-1)" 0.7 0.8 0.7 7.0 0.7 33.0 1.6 2.3 0.7 1.8 1.1 6.2 5.5 1.8 0.7 7.3 0.9 1.3 1.3 0.6 1.1 0.8 0.7 1.3 16.4 1.1 0.9 0.6 0.5 1.3 0.4 5.4 1.4 0.8 7.6 0.8 1.3 0.7 0.9 6.0 5.1 3.2 0.9 3.7 3.5 76.5 0.8 37.4 1.1 0.7 19.2 2.1 2.7 0.8 119.7 45.8 99.6 79.8 5.3 11.6 66.6 86.9 62.1 175.0 151.3 77.6 84.2 136.2 41.3 43.2 121.7 55.2 102.8 59.6 158.2 89.1 44.4 162.1 83.3 65.5 0.6 121.5 71.8 2.7 5.8 125.0 60.3 16.5 57.6 95.4 130.4 113.1 112.4 46.5 127.5 72.9 97.1 58.4 56.5 101.1 149.3 86.4 29.6 42.8 68.3 48.5 116.1 81.6 71.5 71.9 47.2 90.7 34.7 62.9 124.2 69.0 155.6 59.4 65.0 195.3 40.3 115.4 123.9 0.0 0.0 0.0 0.9 0.0 0.0 0.6 1.7 1.2 0.1 0.1 0.3 0.2 0.0 2.0 0.1 0.8 2.9 0.5 0.7 0.7 2.3 0.7 0.6 1.1 1.1 0.9 1.4 0.9 0.8 0.8 0.1 0.0 0.5 1.6 1.3 1.8 0.5 2.4 0.0 1.0 0.9 0.9 1.6 0.0 1.7 1.8 2.1 12.2 1.9 2.9 1.9 0.3 461.1 1.2 1.4 1.6 0.0 34.5 0.8 0.4 23.4 3.2 3.1 2.1 0.0 13.0 2.9 0.2 9.2 0.0 1.0 3.5 0.0 1.9 1.5 1860.6 9.3 3.4 0.0 1.0 4.3 0.4 0.0 0.5 0.2 0.1 0.2 6.8 7.8 0.8 0.3 0.2 0.3 0.2 6.6 0.8 3.4 60.6 36.8 4.6 0.4 3.7 2.7 0.8 7.4 0.7 KIF4A "FLJ12530, FLJ12655, FLJ14204, FLJ20631, HSA271784, KIF4, KIF4-G1, MRX100" ENSG00000090889 "Kinesin family member 4A" O95239 X 70290104-70420886 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA-binding, Motor protein" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.2;lymphoid tissue: 12.6" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 18.6;Erythroid cells: 29.5;Extravillous trophoblasts: 11.5;Granulosa cells: 12.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA034745, HPA034746, HPA061583" Approved Supported Nucleoplasm,Midbody Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Midbody" "HPA034745: AB_10670978, HPA034746: AB_10670173, HPA061583: AB_2684564" "unprognostic (8.17e-3)" "unprognostic (2.78e-2)" "unprognostic (1.02e-2)" "unprognostic (3.46e-3)" "unprognostic (3.20e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (7.37e-6)" "unprognostic (2.18e-3)" "unprognostic (5.06e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (9.44e-6)" "unprognostic (3.79e-2)" "unprognostic (0.00e+0)" "unprognostic (3.09e-2)" "unprognostic (1.10e-1)" "unprognostic (1.09e-1)" "unprognostic (1.47e-1)" 0.3 0.3 0.3 3.2 0.2 11.2 0.7 0.1 0.3 0.6 0.3 3.7 3.1 0.8 0.0 3.6 1.5 0.5 0.2 0.2 0.5 0.2 0.5 0.5 5.5 0.9 0.7 0.1 0.1 0.1 0.5 2.3 0.6 0.1 4.5 0.6 0.5 0.1 0.1 2.2 3.3 1.3 0.7 2.4 1.7 1.5 0.6 12.6 0.2 0.0 6.6 0.9 1.1 0.2 60.2 41.1 61.0 30.1 2.9 5.1 24.0 44.7 23.8 59.7 51.6 46.7 34.3 36.7 27.4 22.1 46.2 35.1 66.6 24.2 66.8 42.5 33.4 41.7 50.1 33.4 0.7 46.7 27.8 1.7 1.5 49.6 28.2 7.3 37.0 27.7 53.8 79.1 57.0 38.7 43.0 23.1 61.7 63.8 43.2 47.1 82.2 34.6 14.5 23.4 40.1 33.5 72.9 30.5 18.6 30.6 24.5 18.1 26.0 39.3 50.6 42.6 54.1 22.6 41.7 52.0 20.8 50.4 60.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.2 0.1 0.3 0.2 0.5 0.9 0.7 0.6 0.7 0.6 0.2 0.1 0.0 0.5 1.3 1.3 1.8 0.3 1.4 0.6 0.2 1.1 0.8 0.4 1.5 0.2 0.0 0.0 7.0 0.9 2.2 0.0 0.0 0.4 18.6 1.5 1.3 1.2 29.5 1.9 0.0 11.5 2.1 3.1 1.6 0.0 12.2 1.1 0.1 5.3 0.0 1.9 4.6 2.0 1.3 0.7 0.8 0.0 1.4 0.0 0.0 0.2 3.1 0.0 2.0 0.7 0.1 0.1 0.0 8.2 0.4 0.3 0.1 0.4 0.0 0.0 0.2 2.9 8.7 5.4 7.2 0.3 1.8 1.8 1.3 6.6 0.5 KIF4B ENSG00000226650 "Kinesin family member 4B" Q2VIQ3 5 155013755-155018141 "Plasma proteins, Predicted intracellular proteins" "DNA-binding, Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 19 "testis: 3.5" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Early spermatids: 5.4;Late spermatids: 4.3;Spermatocytes: 9.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA034745, HPA034746, HPA061583" Uncertain Uncertain Nucleoplasm,Midbody Yes NA "Cluster 78: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Midbody" "HPA034745: AB_10670978, HPA034746: AB_10670173, HPA061583: AB_2684564" "unprognostic (9.87e-3)" "unprognostic (1.17e-1)" "unprognostic (3.91e-3)" "unprognostic (1.71e-1)" "unprognostic (9.14e-2)" "unprognostic (1.71e-1)" "unprognostic (4.76e-2)" "unprognostic (1.94e-1)" "unprognostic (1.06e-1)" "unprognostic (4.37e-2)" "unprognostic (6.48e-9)" "unprognostic (7.24e-2)" "unprognostic (5.10e-2)" "unprognostic (1.71e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 4.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 9.2 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 KIF5A "D12S1889, MY050, NKHC, SPG10" ENSG00000155980 "Kinesin family member 5A" Q12840 12 57546026-57586633 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Amyotrophic lateral sclerosis, Disease variant, Epilepsy, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 27 "brain: 1628.2;choroid plexus: 951.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 40.7;Early spermatids: 12.2;Endometrial stromal cells: 12.9;Excitatory neurons: 28.4;Horizontal cells: 26.9;Inhibitory neurons: 21.7;Late spermatids: 15.2;Rod photoreceptor cells: 11.3" "Cancer enriched" "Detected in some" 5 "glioma: 26.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 33.2;K-562: 15.3;NTERA-2: 17.7;SCLC-21H: 34.4;U-87 MG: 14.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004469, HPA073448" Enhanced Approved "Nucleoplasm,Mitotic spindle,Cytosol" Yes No "Cluster 32: T-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Cytosol" "Mitotic spindle" "HPA004469: AB_1079212, HPA073448: AB_2686601" "unprognostic (7.94e-2)" "unprognostic (4.95e-3)" "unprognostic (3.87e-1)" "unprognostic (3.34e-3)" "unprognostic (7.12e-2)" "unprognostic (4.22e-2)" "unprognostic (3.22e-5)" "unprognostic (2.82e-1)" "unprognostic (2.01e-1)" "unprognostic (1.52e-2)" "prognostic favorable (5.23e-4)" "unprognostic (7.61e-2)" "unprognostic (2.26e-4)" "unprognostic (4.75e-2)" "unprognostic (1.46e-1)" "unprognostic (4.12e-1)" "unprognostic (1.51e-1)" 0.4 10.6 1198.6 4.6 1243.7 4.2 0.5 1056.4 1628.2 2.5 951.3 4.5 3.6 3.8 1.4 1.4 0.6 0.7 0.6 1242.7 1056.4 0.8 0.2 0.8 0.7 1103.5 1046.7 0.6 2.6 9.0 21.3 0.1 1113.3 0.9 1.9 48.0 1.1 0.6 0.3 1.1 2.5 2.0 1002.7 0.8 1.3 4.8 1052.3 0.1 2.3 0.1 0.4 0.5 1.5 1313.2 0.5 0.1 7.2 5.7 0.0 0.0 0.6 1.4 1.3 2.2 3.5 1.2 0.2 3.2 0.4 1.9 1.3 0.8 3.8 0.1 2.5 33.2 4.1 0.5 1.8 7.0 1.9 1.5 1.3 1.0 0.4 1.6 0.1 0.5 0.5 2.8 15.3 9.4 0.0 0.6 0.8 0.0 17.7 0.0 0.0 0.5 0.2 0.3 1.1 0.5 34.4 9.1 0.0 1.6 0.0 2.0 0.9 0.2 0.9 0.6 5.3 1.1 2.1 5.3 7.7 1.9 14.5 0.1 0.6 0.2 0.4 0.1 1.0 0.5 1.6 0.7 0.7 1.2 0.3 0.5 0.9 2.2 1.1 0.3 1.1 0.3 1.0 0.4 1198.6 1243.7 1056.4 1628.2 1242.7 1056.4 1103.5 1046.7 1113.3 1002.7 1052.3 1313.2 0.1 0.0 0.0 2.9 0.1 0.0 0.1 0.0 0.0 40.7 0.1 0.9 2.0 0.0 0.0 0.0 2.1 0.0 0.2 0.0 0.0 0.0 12.2 0.5 12.9 0.7 0.0 0.4 28.4 0.2 0.0 0.3 0.0 0.3 0.0 0.1 0.0 0.0 0.1 26.9 21.7 0.2 0.0 0.0 0.2 15.2 0.0 0.1 0.0 0.0 0.0 6.4 0.0 8.5 3.9 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 11.3 0.0 0.0 0.7 3.3 7.9 0.0 0.1 0.0 0.3 0.0 0.1 0.1 KLF11 "MODY7, TIEG2, Tieg3" ENSG00000172059 "Kruppel like factor 11" O14901 2 10042849-10054836 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 135.0;Suprabasal keratinocytes: 86.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 47.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058276 Supported "Nucleoplasm,Nuclear bodies,Focal adhesion sites,Cytosol" Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Nuclear bodies, Focal adhesion sites, Cytosol" "HPA058276: AB_2683664" "unprognostic (9.66e-3)" "unprognostic (1.87e-1)" "unprognostic (1.59e-1)" "unprognostic (1.06e-2)" "unprognostic (3.02e-3)" "unprognostic (2.63e-3)" "unprognostic (6.34e-2)" "unprognostic (1.04e-2)" "unprognostic (1.67e-1)" "unprognostic (1.04e-1)" "unprognostic (3.17e-3)" "unprognostic (3.08e-2)" "unprognostic (2.48e-3)" "unprognostic (8.96e-2)" "unprognostic (3.44e-1)" "unprognostic (1.07e-2)" "unprognostic (9.24e-2)" 27.7 15.6 4.0 7.6 3.2 27.8 22.3 8.3 3.9 13.5 4.1 17.9 7.5 20.0 9.7 13.2 13.7 18.1 19.1 2.9 3.9 15.7 35.2 22.4 9.3 3.7 3.3 23.9 54.2 18.3 2.5 19.5 3.4 10.1 9.3 3.0 15.9 14.8 12.1 26.9 8.7 16.8 3.2 18.8 12.4 30.0 3.5 4.0 16.5 27.3 5.5 12.6 13.1 5.1 6.9 3.3 7.8 0.7 5.3 9.4 18.8 7.9 7.9 4.4 4.6 7.8 15.8 0.0 13.9 9.6 17.9 1.6 6.8 6.1 2.9 47.6 5.2 3.5 9.7 1.6 5.2 14.6 22.1 14.7 22.3 8.4 2.3 11.4 3.9 1.3 9.7 30.8 4.6 8.2 0.0 2.7 12.5 5.6 6.7 7.8 0.2 13.6 10.8 8.5 10.0 6.2 12.0 24.5 23.4 12.2 5.7 19.6 11.2 19.3 15.9 14.7 2.6 27.9 36.0 18.7 5.0 3.8 10.4 0.0 8.2 2.0 2.6 12.3 0.8 3.2 1.8 1.9 7.3 2.9 0.5 1.1 0.2 6.6 14.8 0.3 3.0 5.4 4.0 3.2 8.3 3.9 2.9 3.9 3.7 3.3 3.4 3.2 3.5 5.1 58.8 6.4 4.6 0.3 12.5 60.5 17.7 5.5 25.6 6.2 14.3 13.2 3.5 10.0 6.1 7.3 6.2 3.2 10.1 2.5 29.4 8.2 135.0 9.1 21.5 33.3 7.1 4.6 1.7 8.5 4.2 17.5 9.7 26.6 8.2 15.5 37.5 38.1 12.5 3.3 1.4 7.0 16.2 32.4 42.4 25.9 14.6 22.0 30.2 1.0 16.6 2.2 3.1 0.5 0.3 8.9 1.5 16.6 5.3 15.0 6.1 8.4 4.3 5.8 32.9 10.4 35.7 13.8 39.0 13.1 86.2 8.2 10.8 11.2 7.8 11.7 KLHDC4 DKFZp434G0522 ENSG00000104731 "Kelch domain containing 4" Q8TBB5 16 87696485-87765992 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 61.6;Late spermatids: 79.9;NK-cells: 77.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 112.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041665 Approved Approved "Nucleoli,Mitotic chromosome" Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoli "Mitotic chromosome" "HPA041665: AB_10796352" "unprognostic (2.96e-2)" "unprognostic (2.31e-2)" "unprognostic (1.28e-3)" "unprognostic (3.54e-1)" "unprognostic (2.94e-1)" "unprognostic (2.26e-2)" "unprognostic (7.61e-3)" "unprognostic (6.40e-2)" "unprognostic (1.20e-1)" "unprognostic (2.87e-1)" "prognostic favorable (1.14e-4)" "unprognostic (3.84e-2)" "unprognostic (2.73e-2)" "unprognostic (1.54e-1)" "unprognostic (4.56e-2)" "unprognostic (3.88e-1)" "prognostic favorable (1.69e-4)" 10.6 10.8 7.6 11.6 7.2 13.3 10.7 11.7 9.0 11.8 5.2 14.0 8.9 11.6 4.4 11.9 12.0 6.7 8.9 7.8 7.7 14.0 14.6 11.4 16.1 7.6 7.0 12.2 18.4 10.3 13.1 5.4 7.4 13.2 10.9 6.2 11.8 7.8 12.5 11.9 13.7 7.1 6.3 19.8 14.0 12.5 7.3 15.6 13.1 6.4 13.4 11.5 12.9 7.1 16.6 29.7 14.8 22.8 6.0 7.9 23.3 15.1 14.5 24.8 11.6 43.9 23.3 25.6 19.6 12.1 8.8 26.6 23.1 20.0 18.0 4.2 24.9 15.0 20.6 29.4 14.9 14.3 14.8 3.6 10.7 21.9 25.0 12.4 20.8 42.5 48.3 13.4 17.1 72.0 32.7 40.3 25.5 18.9 21.8 31.3 17.3 15.3 15.0 19.2 22.5 21.4 31.9 16.4 7.8 12.6 25.8 22.0 13.4 13.1 23.3 7.1 29.5 63.2 23.4 112.0 13.2 35.2 9.7 0.0 7.8 5.9 18.3 10.8 16.2 7.8 7.2 14.1 6.0 7.7 7.3 11.3 0.6 25.7 16.0 8.0 6.8 8.7 7.6 7.2 11.7 9.0 7.8 7.7 7.6 7.0 7.4 6.3 7.3 7.1 8.4 0.0 16.8 11.1 14.7 4.6 10.9 6.8 12.5 17.8 12.7 9.9 9.9 14.3 14.2 9.2 27.1 14.4 36.1 16.5 11.7 12.3 61.6 8.9 6.0 8.8 24.0 16.0 9.1 16.7 9.4 9.0 19.4 11.4 3.8 17.7 12.1 13.3 13.3 11.8 10.1 15.9 8.2 13.3 6.1 79.9 6.5 9.9 8.8 7.5 10.2 6.5 77.2 7.1 9.2 13.1 9.3 7.5 35.9 15.1 13.8 25.1 9.0 18.0 0.0 16.7 8.5 22.8 11.8 8.6 6.7 11.9 25.5 11.6 21.8 16.5 KLHDC9 KARCA1 ENSG00000162755 "Kelch domain containing 9" Q8NEP7 1 161098361-161100346 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 29.0" "Group enriched" "Detected in many" 4 "Early spermatids: 424.7;Late spermatids: 448.2;Spermatocytes: 198.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 2.1;HDLM-2: 1.5;HEK 293: 1.8;MCF7: 1.4;T-47d: 1.4;U-266/70: 1.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043197 Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes NA "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nucleoli, Nucleoli rim, Mitotic chromosome" "HPA043197: AB_2678359" "unprognostic (1.79e-1)" "unprognostic (2.26e-1)" "unprognostic (4.71e-2)" "unprognostic (1.04e-3)" "unprognostic (2.53e-2)" "unprognostic (1.52e-1)" "unprognostic (1.62e-1)" "unprognostic (4.87e-3)" "unprognostic (6.31e-2)" "prognostic favorable (4.20e-6)" "unprognostic (1.81e-3)" "unprognostic (1.71e-1)" "unprognostic (1.12e-1)" "unprognostic (3.53e-1)" "unprognostic (5.51e-2)" "unprognostic (6.36e-2)" "unprognostic (6.88e-2)" 0.4 3.0 1.3 0.1 1.8 0.0 0.7 1.0 2.9 1.1 2.1 1.4 0.2 1.4 0.5 0.5 2.2 0.0 0.9 1.7 2.2 4.7 1.9 0.8 0.0 1.7 1.8 1.0 2.4 1.1 4.6 0.0 1.6 1.7 0.2 0.4 1.0 0.4 0.7 0.3 0.8 0.0 1.2 0.3 1.3 29.0 2.4 0.0 2.4 0.1 0.1 1.0 0.5 0.9 0.1 1.1 0.4 1.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.7 0.0 0.0 0.0 1.5 1.8 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.5 0.2 0.9 1.0 0.0 0.7 0.2 0.0 1.0 0.4 0.0 0.4 0.0 0.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.8 1.0 2.9 1.7 2.2 1.7 1.8 1.6 1.2 2.4 0.9 2.4 0.0 6.7 8.8 1.5 0.9 11.7 11.5 0.6 13.7 15.3 16.3 9.3 14.3 11.7 29.5 2.1 2.3 0.4 7.6 56.7 10.2 424.7 57.5 2.8 3.4 5.4 0.0 8.9 5.5 3.6 3.2 3.1 10.3 1.3 1.6 3.9 9.5 0.6 3.3 6.8 10.6 16.2 0.6 0.7 448.2 8.1 0.9 7.2 2.8 0.6 35.1 1.0 6.0 1.7 3.9 8.2 8.2 2.1 6.4 2.5 47.8 77.8 20.0 13.1 2.8 4.4 198.1 15.6 2.6 0.9 0.8 1.2 1.7 8.7 8.2 KLHL22 "FLJ14360, KELCHL" ENSG00000099910 "Kelch like family member 22" Q53GT1 22 20441519-20495844 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 41.1;Excitatory neurons: 42.9;Inhibitory neurons: 51.1;Oligodendrocyte precursor cells: 41.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040766 Supported "Vesicles,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes No "Cluster 2: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA040766: AB_2732488" "unprognostic (4.15e-1)" "unprognostic (9.34e-3)" "unprognostic (5.37e-2)" "prognostic favorable (4.88e-6)" "unprognostic (1.17e-1)" "unprognostic (2.30e-3)" "unprognostic (1.00e-2)" "unprognostic (1.19e-3)" "unprognostic (2.20e-1)" "unprognostic (8.99e-2)" "prognostic favorable (3.85e-6)" "unprognostic (3.94e-2)" "prognostic favorable (1.34e-8)" "unprognostic (3.94e-2)" "unprognostic (3.10e-1)" "unprognostic (4.64e-2)" "unprognostic (1.08e-2)" 13.7 14.2 24.1 10.2 23.0 11.3 11.9 25.9 25.1 20.5 18.2 16.6 7.7 20.4 17.2 8.0 17.9 13.6 14.2 22.9 21.4 15.6 10.8 11.8 17.6 18.0 18.1 22.3 16.5 22.9 19.6 11.6 18.7 18.7 10.6 15.3 14.0 18.0 22.1 11.7 10.4 21.7 14.8 15.6 12.2 10.2 23.1 8.0 20.8 18.0 20.7 13.4 10.9 21.2 17.1 16.5 37.5 29.9 30.6 35.5 9.0 21.4 37.6 21.0 23.6 8.2 6.4 11.9 7.0 37.3 16.9 21.3 25.6 9.2 18.1 25.9 15.1 12.6 17.4 8.3 30.6 2.6 11.7 26.9 14.2 19.3 12.4 26.8 31.3 9.1 32.7 11.4 20.7 25.9 2.5 15.6 6.3 14.1 11.4 23.5 13.8 0.5 12.3 19.9 19.9 20.3 23.0 16.9 15.8 12.3 15.7 9.3 14.2 25.1 12.2 17.5 8.9 6.4 7.4 7.9 13.5 11.1 16.6 8.9 4.6 19.3 8.1 6.3 6.4 8.3 10.2 7.5 15.5 6.2 7.7 8.3 10.6 16.6 8.3 5.6 19.2 6.5 24.1 23.0 25.9 25.1 22.9 21.4 18.0 18.1 18.7 14.8 23.1 21.2 4.6 0.0 3.7 41.1 8.2 1.7 2.8 8.4 4.0 11.7 4.3 5.2 4.8 10.0 5.3 9.2 4.2 17.9 5.2 2.9 3.9 8.4 0.8 3.2 7.1 4.8 3.0 1.3 42.9 2.6 6.6 9.2 5.1 3.9 5.1 14.2 4.2 6.3 7.9 13.5 51.1 5.2 12.2 5.7 4.9 1.8 12.2 4.8 1.8 16.9 4.2 13.9 7.2 41.2 26.8 5.6 3.5 19.9 5.4 3.9 3.0 10.9 4.3 6.7 6.6 4.7 5.3 17.3 15.4 2.8 1.4 13.4 7.8 17.7 3.8 1.8 KLHL38 C8ORFK36 ENSG00000175946 "Kelch like family member 38" Q2WGJ6 8 123645527-123652950 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 56.7;skeletal muscle: 268.3;tongue: 76.9" "Cell type enriched" "Detected in single" 10 "Cardiomyocytes: 1.0" "Group enriched" "Detected in some" 5 "breast cancer: 1.3;melanoma: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.7;SK-BR-3: 2.8;U-2197: 4.9" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA024770, HPA027115" Uncertain Approved Nucleoplasm,Cytosol Yes NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 18: U-2197 - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm Cytosol "HPA024770: AB_10599286, HPA027115: AB_10599950" "unprognostic (8.62e-3)" "unprognostic (3.86e-3)" "unprognostic (1.02e-2)" "unprognostic (8.94e-2)" "unprognostic (4.68e-1)" "unprognostic (2.09e-2)" "unprognostic (8.20e-2)" "unprognostic (2.13e-1)" "unprognostic (1.54e-1)" "unprognostic (4.02e-1)" "unprognostic (1.19e-1)" "unprognostic (5.77e-2)" "unprognostic (5.73e-6)" "unprognostic (8.46e-3)" "unprognostic (3.82e-2)" "unprognostic (6.52e-2)" "unprognostic (2.84e-2)" 0.2 0.0 0.1 0.2 0.2 0.0 0.2 0.0 0.5 0.2 0.1 0.9 0.1 1.3 0.0 2.5 0.7 0.7 56.7 0.2 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.5 0.1 1.3 0.0 1.5 0.0 0.8 0.1 0.0 0.7 0.1 268.3 0.2 0.2 2.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 76.9 0.0 0.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.9 0.0 0.5 0.0 0.0 0.0 0.1 4.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KLHL6 FLJ00029 ENSG00000172578 "Kelch like family member 6" Q8WZ60 3 183487551-183555706 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 31.0" "Cell type enhanced" "Detected in many" "B-cells: 35.7;Endometrial ciliated cells: 28.3;granulocytes: 51.1;Hofbauer cells: 24.1;Macrophages: 33.3;Plasma cells: 63.6;Respiratory ciliated cells: 24.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 41.3;HEL: 26.6;HMC-1: 26.7;U-266/70: 82.1;U-266/84: 45.5;U-698: 121.3" "Low region specificity" "Detected in all" HPA024512 Uncertain Approved "Plasma membrane,Microtubules,Mitotic spindle,Centriolar satellite" Yes NA "Cluster 2: Granulocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Centriolar satellite" "Plasma membrane, Microtubules, Mitotic spindle" "HPA024512: AB_2131015" "unprognostic (8.46e-2)" "unprognostic (3.67e-4)" "unprognostic (1.48e-2)" "unprognostic (6.03e-4)" "unprognostic (5.15e-2)" "unprognostic (1.30e-3)" "unprognostic (1.39e-1)" "unprognostic (5.05e-2)" "unprognostic (7.43e-2)" "unprognostic (9.62e-2)" "unprognostic (8.24e-2)" "unprognostic (2.68e-1)" "prognostic unfavorable (3.53e-4)" "unprognostic (1.81e-1)" "unprognostic (3.68e-2)" "unprognostic (2.42e-1)" "unprognostic (5.73e-2)" 1.5 0.7 0.7 11.8 0.8 3.5 0.9 1.0 1.0 0.8 0.7 2.5 2.5 0.6 0.2 0.6 4.8 2.1 0.7 0.6 1.4 0.4 1.0 4.2 29.3 2.6 1.4 0.3 0.6 0.2 0.2 1.9 2.0 0.5 2.3 0.1 1.3 0.1 0.2 0.1 4.8 0.7 1.5 6.3 4.1 0.2 3.1 10.0 0.6 0.3 31.0 1.8 0.3 3.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 21.9 0.0 26.6 0.0 0.0 0.0 7.3 26.7 0.0 0.0 0.0 0.0 0.0 4.6 0.5 0.4 18.4 0.0 0.0 8.8 4.1 0.0 0.0 0.0 14.8 0.1 7.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 2.5 0.0 0.1 0.0 0.1 82.1 45.5 121.3 0.0 8.0 0.0 7.8 2.8 11.8 0.6 2.2 0.7 3.6 2.4 1.0 2.0 2.4 2.9 1.8 2.4 2.2 2.7 4.6 4.2 2.6 0.7 0.8 1.0 1.0 0.6 1.4 2.6 1.4 2.0 1.5 3.1 3.7 4.0 6.4 6.5 0.7 35.7 1.1 1.7 0.6 0.6 0.6 0.3 0.4 4.8 0.0 5.4 0.0 2.1 0.2 16.6 0.2 0.0 0.1 2.0 28.3 0.5 4.6 0.0 7.6 0.3 0.0 0.3 1.7 2.0 0.8 51.1 8.1 1.1 0.2 24.1 0.0 0.3 0.0 0.0 20.7 22.4 0.8 0.3 33.3 8.8 14.0 10.1 0.3 5.2 1.0 0.3 0.0 0.1 0.0 63.6 1.2 0.0 0.4 24.4 0.7 0.0 1.8 1.5 0.3 0.4 0.1 0.6 0.5 16.8 0.0 0.2 1.2 KLK6 "Bssp, Klk7, neurosin, PRSS18, PRSS9" ENSG00000167755 "Kallikrein related peptidase 6" Q92876 19 50958631-50969673 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 253.0;esophagus: 94.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 23.9;Breast myoepithelial cells: 16.1;Collecting duct cells: 11.0;Oligodendrocytes: 87.9" "Cancer enhanced" "Detected in many" "ovarian cancer: 131.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "A-431: 575.5;CAPAN-2: 1346.5" "Region enhanced" "Detected in all" "pons and medulla: 167.8" "Region enhanced" "Detected in many" "spinal cord: 371.7" HPA051837 Supported "Nucleoplasm,Nuclear membrane,Cytokinetic bridge" "Secreted in other tissues" Yes No 10000000 "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 30: Mammary glandular cells - Lactation" Nucleoplasm "Nuclear membrane, Cytokinetic bridge" "HPA051837: " "unprognostic (7.30e-2)" "unprognostic (3.32e-1)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.38e-5)" "unprognostic (1.10e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (8.85e-4)" "unprognostic (3.02e-1)" "unprognostic (2.46e-1)" "prognostic unfavorable (7.82e-4)" "unprognostic (4.45e-1)" "unprognostic (2.72e-2)" "unprognostic (1.31e-1)" "unprognostic (2.46e-1)" "unprognostic (9.07e-2)" "prognostic unfavorable (1.27e-4)" 0.2 0.0 71.8 0.0 135.8 0.0 7.2 170.8 119.8 53.1 45.6 0.1 0.2 1.5 0.4 94.2 28.9 3.5 0.0 72.9 94.3 20.4 0.0 0.0 0.0 213.8 130.8 0.8 0.0 0.0 0.7 0.0 182.1 0.1 0.0 0.0 15.8 2.2 0.0 9.9 0.0 0.0 123.6 5.8 0.1 0.9 118.1 1.5 0.0 0.0 36.4 0.0 27.4 253.0 575.5 0.0 0.0 1.4 0.0 0.0 2.2 0.0 0.0 0.0 0.0 67.7 1346.5 0.0 8.1 0.0 0.6 8.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 1.1 131.0 2.2 0.1 0.0 0.0 16.2 0.0 0.0 0.0 0.0 0.0 5.6 18.2 1.0 1.9 0.0 1.1 46.3 0.0 1.3 0.0 0.4 0.3 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.8 135.8 170.8 119.8 72.9 94.3 213.8 130.8 182.1 123.6 118.1 253.0 0.2 0.0 0.0 0.0 0.2 0.0 1.0 0.5 0.0 0.0 23.9 16.1 0.3 0.0 1.7 11.0 0.0 0.1 0.4 0.0 0.0 0.1 2.3 0.6 7.5 0.4 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 3.7 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.5 87.9 7.8 0.0 0.0 0.0 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.9 0.3 1.6 0.0 0.3 0.1 0.0 0.0 2.4 KMT2D "ALR, CAGL114, MLL2, MLL4, TNRC21" ENSG00000167548 "Lysine methyltransferase 2D" O14686 12 49018978-49060794 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035977 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "Nucleoplasm, Plasma membrane" "HPA035977: AB_10670673" "unprognostic (8.33e-2)" "unprognostic (1.49e-1)" "unprognostic (9.14e-2)" "unprognostic (2.52e-1)" "unprognostic (8.07e-2)" "unprognostic (6.91e-3)" "unprognostic (7.35e-2)" "unprognostic (2.29e-1)" "unprognostic (3.57e-1)" "unprognostic (5.14e-2)" "unprognostic (7.23e-2)" "unprognostic (3.07e-1)" "unprognostic (1.68e-2)" "unprognostic (7.10e-2)" "unprognostic (1.87e-1)" "unprognostic (3.20e-2)" "unprognostic (7.60e-2)" 19.9 21.9 14.0 17.0 14.4 62.1 20.3 14.7 18.1 20.2 3.8 21.3 13.2 26.9 14.4 25.5 24.1 11.7 23.7 12.1 9.1 18.2 20.5 25.1 17.5 9.3 8.2 25.3 33.2 22.9 25.4 16.2 8.6 19.2 14.7 48.0 22.1 16.2 44.9 30.4 27.9 15.5 3.1 36.6 25.5 23.6 12.7 29.0 26.5 21.9 17.2 19.4 19.4 13.4 32.3 31.9 31.0 24.7 29.3 20.4 32.6 17.3 17.1 20.3 10.9 54.8 14.1 33.4 21.2 23.9 14.0 21.5 38.1 19.9 17.7 22.4 26.7 47.2 37.7 29.9 20.5 59.1 43.2 18.4 25.8 30.7 32.0 27.3 31.8 33.2 55.1 19.2 23.7 37.4 26.8 48.0 29.9 45.4 25.0 37.4 22.4 12.0 18.1 37.2 24.6 21.2 28.1 25.5 19.5 26.1 24.0 44.1 49.8 15.5 30.7 14.5 30.5 24.8 20.9 31.7 17.1 28.0 12.5 0.5 0.2 0.3 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 1.5 0.5 0.0 0.2 0.0 0.1 14.0 14.4 14.7 18.1 12.1 9.1 9.3 8.2 8.6 3.1 12.7 13.4 12.9 9.6 19.1 17.6 13.3 14.0 7.8 8.1 14.2 26.8 12.1 7.1 7.8 12.8 10.9 18.4 52.1 8.2 15.3 12.3 1.9 6.3 2.8 10.7 12.7 13.2 13.1 16.0 17.4 6.0 6.0 8.8 24.5 13.1 8.2 23.3 17.9 13.0 9.8 21.9 16.5 10.0 6.1 15.7 18.4 2.4 9.6 15.4 10.6 15.0 14.9 6.4 17.5 12.5 19.8 8.8 9.5 10.9 10.1 11.0 13.3 4.5 9.0 38.4 6.6 14.4 12.5 6.5 3.8 18.9 17.6 11.4 15.3 10.8 10.3 9.6 KNL1 "AF15Q14, CASC5, CT29, D40, hKNL-1, hSpc105, KIAA1570, MCPH4, PPP1R55, Spc7" ENSG00000137812 "Kinetochore scaffold 1" Q8NG31 15 40594020-40664342 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 5.3;lymphoid tissue: 7.4;testis: 16.9" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 8.5;Extravillous trophoblasts: 11.3;Granulosa cells: 22.8;Hofbauer cells: 7.1;Proximal tubular cells: 11.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "HPA026624, HPA049647" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" Yes Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA026624: AB_10601696, HPA049647: AB_2680840" "unprognostic (5.35e-2)" "unprognostic (1.01e-1)" "unprognostic (5.59e-3)" "unprognostic (4.22e-2)" "unprognostic (1.59e-2)" "unprognostic (5.66e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (2.06e-2)" "unprognostic (1.43e-1)" "unprognostic (3.20e-4)" "unprognostic (2.22e-2)" "unprognostic (1.93e-12)" "unprognostic (3.07e-2)" "unprognostic (3.08e-1)" "unprognostic (8.45e-2)" "unprognostic (7.36e-2)" 0.2 0.1 0.1 1.9 0.0 5.3 0.3 0.2 0.2 0.2 0.2 1.3 1.6 0.3 0.2 1.0 0.1 0.3 0.1 0.1 0.1 0.5 0.7 0.4 3.6 0.1 0.3 0.0 0.0 0.3 0.0 1.3 0.1 0.1 1.4 0.2 0.2 0.0 0.0 0.8 1.7 0.7 0.0 0.6 0.9 16.9 0.3 7.4 0.3 0.1 3.4 0.5 0.2 0.1 19.1 9.3 18.0 13.8 0.5 2.6 8.6 20.5 8.1 16.0 13.1 11.6 7.2 11.9 6.1 9.3 12.0 21.9 17.6 9.7 16.3 21.4 5.0 35.5 15.5 3.9 0.0 26.2 17.8 0.5 0.4 10.8 6.4 2.1 13.8 20.9 22.9 19.2 18.3 6.1 23.5 6.1 9.4 11.3 9.5 21.2 25.8 5.9 2.6 15.6 15.9 7.7 17.7 10.6 2.1 5.9 11.1 9.0 13.1 18.7 16.3 21.9 11.7 7.5 27.9 22.3 7.6 18.5 18.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.3 0.5 0.0 0.1 0.1 0.1 0.1 0.0 0.6 0.0 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.3 0.1 0.0 0.3 0.1 0.3 0.0 0.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.1 1.1 0.0 0.0 1.8 1.8 0.0 8.5 2.6 0.0 1.9 0.2 0.0 3.5 3.5 1.9 0.0 0.0 0.0 0.6 11.3 4.2 0.0 2.9 0.0 22.8 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.1 0.0 0.0 11.5 0.7 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 3.7 1.9 1.7 0.0 0.0 KNSTRN "C15orf23, FLJ14502, kinastrin, SKAP, TRAF4AF1" ENSG00000128944 "Kinetochore localized astrin (SPAG5) binding protein" Q9Y448 15 40382721-40394246 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 63.6;thyroid gland: 53.1" "Cell type enhanced" "Detected in many" "Early spermatids: 328.2;Late spermatids: 600.1;Spermatocytes: 145.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" HPA042027 Enhanced Enhanced "Plasma membrane,Mitotic spindle,Centriolar satellite" Yes Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" "Mitotic spindle, Centriolar satellite" "Plasma membrane" "HPA042027: AB_10797378" "unprognostic (2.35e-3)" "unprognostic (6.83e-2)" "unprognostic (3.01e-1)" "unprognostic (5.23e-3)" "unprognostic (6.19e-2)" "unprognostic (2.28e-2)" "unprognostic (1.54e-3)" "unprognostic (2.47e-3)" "unprognostic (1.23e-1)" "unprognostic (2.55e-1)" "prognostic unfavorable (3.43e-5)" "unprognostic (6.31e-2)" "prognostic unfavorable (7.88e-9)" "unprognostic (1.70e-1)" "unprognostic (1.58e-1)" "unprognostic (2.67e-1)" "unprognostic (1.52e-2)" 8.0 6.2 6.3 8.1 7.1 14.1 14.3 7.7 8.6 5.1 4.5 7.9 9.2 6.4 12.3 9.1 5.7 4.4 7.4 7.2 6.2 7.2 12.0 5.8 14.5 6.2 6.2 5.1 5.0 8.4 5.6 10.7 6.5 6.8 10.4 9.0 10.3 7.2 12.2 6.7 6.2 10.2 5.9 7.1 10.2 63.6 6.1 25.6 53.1 12.4 16.1 5.6 5.6 7.7 103.4 47.5 92.7 61.0 20.1 30.9 48.1 69.9 54.0 141.0 123.3 102.6 44.2 39.7 34.8 47.3 112.1 115.7 100.0 64.8 126.5 70.8 48.8 117.7 107.4 65.2 18.9 63.8 58.6 16.1 36.5 71.3 70.6 34.5 80.3 97.6 86.3 66.8 120.0 52.2 55.6 51.2 58.6 87.7 71.2 56.4 69.7 45.7 49.7 42.3 89.9 62.5 58.3 63.3 15.1 55.8 66.5 45.3 41.6 67.5 68.8 69.7 98.3 56.5 98.6 70.5 41.8 84.0 56.5 13.2 17.6 17.4 7.9 24.3 6.8 9.5 5.7 7.0 18.4 11.2 5.4 5.5 9.7 9.8 47.8 12.7 9.4 7.1 6.3 7.1 7.7 8.6 7.2 6.2 6.2 6.2 6.5 5.9 6.1 7.7 2.4 9.6 1.1 2.6 4.1 2.2 2.9 7.6 3.4 8.2 4.2 3.4 7.3 1.5 5.4 0.0 8.4 25.2 2.5 1.9 3.9 8.5 328.2 5.9 4.9 3.7 2.4 34.3 5.1 9.3 40.8 5.2 5.6 4.4 1.3 16.9 3.6 8.0 21.6 5.0 4.9 5.3 14.2 9.8 2.0 600.1 9.0 8.2 3.6 4.7 8.0 8.5 6.2 2.0 4.3 12.3 0.5 7.2 12.6 4.9 2.8 5.8 7.2 8.5 0.0 3.7 6.5 145.7 19.2 7.0 1.4 21.1 5.1 8.5 6.4 3.0 KPNA2 "IPOA1, QIP2, RCH1, SRP1alpha" ENSG00000182481 "Karyopherin subunit alpha 2" P52292 17 68035636-68047364 "Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 209.1" "Cell type enhanced" "Detected in all" "Early spermatids: 863.9;Extravillous trophoblasts: 279.7;Spermatocytes: 552.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015460, HPA041270" Enhanced Enhanced Nucleoplasm,Cytosol Yes Yes 160000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "CAB015460: AB_831493, HPA041270: AB_2677385" "unprognostic (2.78e-2)" "unprognostic (1.54e-1)" "prognostic favorable (3.83e-4)" "unprognostic (2.14e-2)" "unprognostic (1.64e-1)" "unprognostic (5.16e-3)" "prognostic unfavorable (2.12e-10)" "prognostic unfavorable (5.77e-4)" "unprognostic (3.34e-2)" "unprognostic (7.59e-2)" "unprognostic (3.72e-3)" "unprognostic (3.08e-2)" "prognostic unfavorable (1.26e-13)" "unprognostic (3.07e-2)" "unprognostic (1.78e-1)" "unprognostic (9.50e-2)" "prognostic unfavorable (2.19e-4)" 25.9 15.9 18.9 45.2 19.3 99.2 15.2 18.7 23.3 17.4 15.7 30.7 26.1 17.6 25.7 41.4 10.8 19.4 23.9 20.8 24.7 16.2 23.1 17.9 72.1 19.1 20.5 6.5 10.0 10.6 15.6 43.8 22.2 8.2 35.8 22.2 15.4 11.6 14.8 21.0 23.3 34.6 20.5 28.3 19.0 209.1 20.0 94.7 10.9 16.7 104.9 38.6 17.7 22.7 556.0 712.3 667.1 264.4 95.7 93.9 421.1 467.9 372.9 758.1 587.9 499.5 250.4 514.4 146.7 273.4 375.1 297.4 753.8 359.4 870.7 203.8 437.5 446.5 311.7 482.7 101.9 387.6 294.3 58.1 69.3 426.0 267.2 105.8 746.8 211.0 360.8 346.0 686.1 517.3 484.4 249.8 451.4 455.2 365.8 271.5 605.1 280.6 304.0 250.0 262.2 286.3 269.5 839.1 291.9 609.6 495.6 196.9 288.6 416.7 506.2 290.6 647.3 291.5 451.9 504.7 203.0 334.9 458.0 30.1 31.0 12.7 24.1 46.5 19.2 45.8 18.8 27.3 56.2 39.6 13.3 21.5 0.9 43.9 39.6 41.4 37.7 31.3 18.9 19.3 18.7 23.3 20.8 24.7 19.1 20.5 22.2 20.5 20.0 22.7 41.0 12.8 31.0 6.2 49.4 109.7 32.2 73.7 43.3 20.1 39.8 45.5 13.8 7.2 39.7 18.4 8.4 128.3 96.4 27.7 15.6 31.4 863.9 70.8 55.1 48.6 42.9 70.9 8.5 25.5 279.7 64.9 31.1 68.0 44.4 68.2 21.8 17.2 126.0 32.0 7.3 27.6 97.6 42.9 132.1 266.6 19.3 60.0 53.4 3.7 72.1 31.2 18.6 6.6 5.9 20.7 11.9 14.7 60.3 27.6 9.3 31.2 22.7 20.0 32.9 52.4 74.1 552.9 185.2 61.3 88.5 118.9 79.8 28.0 49.3 24.2 KPNB1 "IMB1, Impnb, IPO1, IPOB, MGC2155, MGC2156, MGC2157, NTF97" ENSG00000108424 "Karyopherin subunit beta 1" Q14974 17 47649476-47685505 "Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029878, CAB034449, HPA050302" Supported Enhanced "Nucleoplasm,Nuclear membrane,Cytosol" Yes No 1600000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 39: CACO-2 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear membrane" "Nucleoplasm, Cytosol" "CAB034449: AB_2133993, HPA029878: AB_10670041, HPA050302: AB_2681079" "unprognostic (2.57e-1)" "unprognostic (1.15e-1)" "unprognostic (4.33e-3)" "unprognostic (2.81e-2)" "unprognostic (1.18e-1)" "unprognostic (8.15e-2)" "prognostic unfavorable (2.55e-7)" "unprognostic (7.18e-3)" "unprognostic (9.52e-2)" "unprognostic (5.47e-3)" "unprognostic (4.37e-2)" "unprognostic (8.41e-3)" "prognostic unfavorable (8.43e-6)" "unprognostic (1.34e-2)" "unprognostic (1.20e-1)" "unprognostic (1.41e-2)" "unprognostic (3.44e-2)" 57.6 44.9 31.6 74.4 33.6 35.9 53.4 34.7 32.2 49.9 30.5 55.3 35.9 47.5 29.5 66.0 49.6 47.2 53.6 31.2 37.1 48.8 50.6 42.6 81.7 38.2 39.8 64.3 38.1 56.3 28.1 55.4 37.1 44.4 63.6 49.0 39.2 45.7 91.0 38.7 38.8 66.6 37.2 54.0 43.3 100.9 33.9 117.3 57.4 88.3 108.7 79.6 40.5 47.3 273.2 485.0 324.6 259.1 152.8 265.8 271.6 345.4 307.0 441.6 339.3 853.2 161.5 385.8 210.4 343.8 301.8 186.3 607.2 316.3 691.1 212.1 344.7 421.2 408.7 241.6 148.4 485.5 238.9 209.6 140.5 511.7 509.2 202.3 305.8 203.0 461.3 237.5 349.4 288.8 464.9 97.2 270.6 199.4 300.2 250.1 563.3 216.4 156.2 444.2 267.5 240.5 233.3 121.7 176.6 388.4 253.9 157.6 248.7 463.9 264.7 252.8 412.9 258.8 373.0 542.6 216.1 224.2 325.8 3.1 2.9 6.1 4.1 3.6 5.8 4.0 4.7 5.1 1.8 4.0 4.5 4.3 12.2 3.5 4.4 3.0 3.4 2.4 31.6 33.6 34.7 32.2 31.2 37.1 38.2 39.8 37.1 37.2 33.9 47.3 76.8 128.2 71.9 42.7 138.3 125.7 101.1 67.8 165.0 96.5 110.8 89.5 132.7 88.6 75.2 44.1 68.8 132.7 93.9 69.5 41.1 117.1 55.8 71.2 123.1 110.5 123.8 148.7 51.4 119.5 147.5 102.9 72.4 106.3 76.1 147.2 128.8 97.5 124.1 80.8 48.2 82.2 44.7 115.0 91.6 41.7 96.9 102.7 60.5 30.9 152.8 83.4 80.3 39.2 58.2 147.0 69.8 121.5 163.4 149.7 49.2 48.0 60.6 90.2 98.6 107.0 104.6 291.6 186.0 163.9 143.5 158.2 108.1 138.8 128.4 128.1 KRI1 FLJ12949 ENSG00000129347 "KRI1 homolog" Q8N9T8 19 10553085-10566031 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 55.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 177.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043110, HPA043574" Approved Enhanced Nucleoli Yes No "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 59: Non-specific - Transcription" Nucleoli "HPA043110: AB_2678321, HPA043574: AB_2678561" "unprognostic (6.38e-2)" "unprognostic (2.34e-3)" "prognostic unfavorable (9.37e-4)" "unprognostic (6.70e-2)" "unprognostic (2.35e-2)" "unprognostic (5.10e-3)" "prognostic unfavorable (1.21e-4)" "unprognostic (3.46e-2)" "unprognostic (1.68e-2)" "unprognostic (2.51e-2)" "unprognostic (2.30e-2)" "unprognostic (4.43e-2)" "prognostic unfavorable (4.89e-10)" "unprognostic (2.99e-2)" "unprognostic (3.06e-2)" "unprognostic (2.70e-1)" "unprognostic (1.02e-1)" 12.3 11.5 10.6 20.0 11.3 17.1 12.6 11.0 11.8 16.6 11.6 14.3 10.0 13.8 7.6 16.8 14.4 7.1 12.1 10.2 12.0 12.7 13.6 11.2 22.3 11.3 11.0 14.8 15.6 10.3 13.4 8.7 11.1 15.6 7.5 33.8 13.0 8.7 22.3 20.9 17.4 7.3 10.3 22.3 12.5 16.1 11.2 30.6 14.6 9.7 15.1 15.9 15.9 11.9 37.7 17.6 23.6 35.0 13.2 14.3 16.6 34.0 16.1 21.6 20.2 27.1 13.6 55.7 39.2 14.1 18.4 29.1 30.3 27.3 23.9 60.2 67.1 177.2 39.6 18.1 23.4 69.6 61.7 17.7 21.7 31.8 31.4 18.4 13.9 33.2 50.4 56.4 18.7 33.5 72.7 104.3 38.2 30.3 45.0 30.0 30.7 28.4 18.1 32.6 39.2 18.2 40.2 23.4 25.7 20.7 29.5 50.0 16.8 27.9 23.0 74.4 71.9 38.7 48.5 39.7 23.2 56.3 41.6 2.2 4.9 2.9 11.9 5.7 11.0 7.4 7.9 9.7 6.8 8.3 8.7 9.5 0.8 10.3 3.0 16.0 6.5 4.8 10.6 11.3 11.0 11.8 10.2 12.0 11.3 11.0 11.1 10.3 11.2 11.9 8.9 16.0 25.5 6.2 20.4 13.5 11.4 12.2 40.9 15.4 6.4 9.5 8.6 8.6 17.5 14.7 39.6 11.4 15.0 9.5 1.9 8.5 4.6 9.0 17.6 11.0 9.6 26.1 4.0 7.5 8.9 11.0 16.3 10.4 19.6 12.3 10.4 9.0 8.0 11.8 3.7 10.1 8.2 12.5 6.1 5.8 8.4 10.5 8.8 5.6 9.2 11.6 24.7 6.0 7.7 5.6 7.6 9.1 17.4 10.8 9.0 5.0 16.0 55.0 0.0 13.5 9.3 25.3 16.8 28.1 13.8 4.5 26.8 9.0 12.7 8.2 KRR1 "HRB2, RIP-1" ENSG00000111615 "KRR1 small subunit processome component homolog" Q13601 12 75490863-75511636 "Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043433, HPA051690" Approved Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA043433: AB_10960988, HPA051690: AB_2681574" "unprognostic (2.77e-1)" "unprognostic (1.02e-1)" "unprognostic (8.21e-2)" "unprognostic (1.71e-1)" "unprognostic (2.02e-1)" "unprognostic (4.71e-2)" "unprognostic (6.01e-3)" "unprognostic (1.78e-1)" "unprognostic (1.00e-1)" "unprognostic (1.38e-1)" "unprognostic (5.85e-2)" "unprognostic (1.88e-1)" "unprognostic (2.32e-2)" "unprognostic (1.69e-1)" "unprognostic (1.61e-1)" "unprognostic (3.26e-1)" "unprognostic (1.12e-2)" 15.2 14.2 6.5 15.6 7.0 43.9 16.7 9.3 10.4 11.6 7.6 12.5 12.1 15.0 9.0 16.0 9.8 10.0 11.8 6.9 8.2 16.2 20.4 11.5 19.0 6.6 7.3 15.0 10.7 20.3 8.0 14.5 7.0 13.2 10.9 16.0 19.3 9.8 23.5 12.7 10.3 10.9 7.4 12.6 12.7 12.0 7.5 17.9 14.9 22.7 18.0 15.9 9.8 8.2 59.4 48.1 29.2 27.1 21.8 20.1 54.1 51.0 31.7 38.5 24.8 35.7 30.7 62.2 40.3 23.9 39.0 30.5 39.1 43.0 42.4 52.0 39.9 60.9 25.0 41.8 26.4 107.0 37.1 21.3 35.8 44.8 41.7 39.1 26.6 57.4 67.7 19.8 38.2 39.2 63.1 30.8 43.6 32.4 42.4 49.9 56.1 37.4 42.6 73.6 35.4 29.6 48.0 33.7 59.5 27.9 56.2 42.9 34.4 36.2 24.1 37.7 53.2 38.8 52.3 39.0 19.6 37.0 66.2 13.3 3.2 13.2 13.1 6.5 16.4 23.0 18.3 15.0 5.5 20.6 18.6 17.9 1.5 12.9 5.5 15.3 18.2 7.6 6.5 7.0 9.3 10.4 6.9 8.2 6.6 7.3 7.0 7.4 7.5 8.2 62.9 70.5 49.2 13.4 64.0 49.1 104.3 70.3 48.9 56.4 41.1 50.5 25.6 24.3 55.7 40.5 33.3 68.5 86.4 18.7 58.7 50.9 5.4 52.5 63.8 46.7 18.0 55.8 25.3 49.0 55.7 48.2 21.4 62.6 38.0 41.3 31.1 40.9 29.5 74.0 24.3 25.7 46.8 24.2 21.3 7.6 52.5 30.0 12.4 6.5 42.4 66.4 66.9 19.1 16.3 42.8 28.1 53.4 37.9 45.6 19.2 47.0 42.3 55.5 13.1 79.2 50.2 72.6 61.1 46.8 44.3 70.5 65.4 59.6 29.3 63.2 KRT17 PCHC1 ENSG00000128422 "Keratin 17" Q04695 17 41619442-41624842 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 382.1;skin 1: 949.4;urinary bladder: 632.2" "Group enriched" "Detected in many" 5 "Basal prostatic cells: 13196.1;Prostatic glandular cells: 5931.6;Urothelial cells: 8499.3" "Cancer enhanced" "Detected in all" "head and neck cancer: 3317.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "hTCEpi: 20287.9;SiHa: 8539.7" "Not detected" "Not detected" "CAB000029, HPA000452, HPA000453, HPA000539, HPA045062" Enhanced Enhanced "Intermediate filaments" Yes No 610000000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Intermediate filaments" "CAB000029: AB_2133155, HPA000452: AB_1079177, HPA000453: AB_1079176, HPA000539: , HPA045062: AB_2679204" "prognostic favorable (4.44e-4)" "unprognostic (1.43e-1)" "unprognostic (1.15e-1)" "unprognostic (3.65e-3)" "unprognostic (4.46e-2)" "unprognostic (4.34e-1)" "unprognostic (4.36e-3)" "unprognostic (1.32e-2)" "unprognostic (2.27e-1)" "unprognostic (1.29e-1)" "unprognostic (7.86e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (5.74e-4)" "unprognostic (1.82e-1)" "unprognostic (1.77e-1)" "unprognostic (2.20e-1)" "unprognostic (3.89e-1)" 5.1 0.4 4.9 0.8 5.3 2.8 382.1 3.5 5.8 102.2 3.5 2.0 0.8 4.3 14.1 320.4 6.9 1.9 2.7 6.3 3.3 3.1 0.6 9.8 0.3 3.5 3.4 0.9 2.6 0.5 6.6 7.0 3.5 132.4 0.3 0.3 263.2 116.1 0.9 949.4 0.6 1.0 3.4 0.4 2.3 4.5 3.3 142.7 1.6 0.0 97.8 632.2 212.3 4.7 212.5 0.2 0.0 0.0 0.8 0.9 48.8 1.9 0.4 2.8 2.7 16.8 1.9 1.0 14.7 0.2 0.4 2101.7 0.1 2129.1 1.9 0.3 1.6 2.0 910.8 2.0 0.5 1.9 2.2 0.4 20287.9 1.3 1539.9 0.0 1.0 0.0 1.0 1.5 0.4 0.7 0.7 0.3 0.4 237.2 0.0 0.7 3.1 1.7 0.8 770.5 0.3 0.2 8539.7 3.8 0.9 4.8 0.3 1.4 0.8 0.0 401.5 0.2 1.0 0.9 0.4 3.1 1.4 77.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 5.3 3.5 5.8 6.3 3.3 3.5 3.4 3.5 3.4 3.3 4.7 5.6 22.4 7.2 0.3 0.5 139.6 13196.1 338.0 327.8 0.2 158.4 792.8 0.1 0.0 415.8 36.8 0.0 21.5 3.8 0.9 0.0 567.7 0.4 116.9 13.5 54.5 1.8 0.0 3.2 202.1 148.5 87.9 0.0 134.1 3.8 0.0 0.0 0.0 3.8 20.2 0.5 0.6 36.7 0.0 14.1 1.6 2.1 37.5 10.6 3.7 6.7 0.0 0.0 0.5 1.4 1754.5 2.5 212.5 0.0 5931.6 0.1 0.4 100.1 0.0 0.0 0.9 101.0 0.3 0.4 48.2 124.3 5.7 60.8 3.1 0.8 8499.3 KYAT3 "CCBL2, KAT3, KATIII, RBM1, RP11-82K18.3" ENSG00000137944 "Kynurenine aminotransferase 3" Q6YP21 1 88935773-88992953 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Aminotransferase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 70.7;Exocrine glandular cells: 38.2;Extravillous trophoblasts: 39.9;Proximal tubular cells: 35.6;Syncytiotrophoblasts: 83.5;Theca cells: 43.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026538, HPA027168" Enhanced Approved "Nucleoli,Cytokinetic bridge,Cytosol" Yes NA "Cluster 27: Non-specific - Gene expression" "Cluster 1: Thyroid gland - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 7: Non-specific - Mitochondria" Cytosol "Nucleoli, Cytokinetic bridge" "HPA026538: AB_1852076, HPA027168: AB_1852078" "prognostic favorable (3.19e-5)" "unprognostic (3.36e-3)" "unprognostic (1.88e-2)" "unprognostic (1.62e-1)" "unprognostic (2.01e-2)" "prognostic favorable (1.86e-4)" "unprognostic (2.61e-1)" "unprognostic (3.61e-3)" "unprognostic (2.11e-1)" "prognostic favorable (2.80e-4)" "unprognostic (1.04e-1)" "unprognostic (3.17e-1)" "prognostic favorable (5.02e-6)" "unprognostic (1.17e-1)" "unprognostic (1.06e-1)" "unprognostic (2.51e-1)" "unprognostic (2.78e-1)" 19.3 22.5 8.3 16.0 9.3 13.4 29.8 10.0 12.2 18.0 12.3 19.9 22.6 21.3 21.7 26.5 18.3 20.0 11.3 9.4 9.5 30.5 27.4 15.4 22.1 8.5 9.5 25.7 30.0 33.4 15.2 22.7 9.2 21.1 21.7 11.0 20.5 22.1 10.6 18.8 17.4 15.7 8.7 17.6 22.7 9.9 8.7 21.6 26.2 10.0 23.7 24.6 14.9 8.9 55.1 11.1 52.2 18.0 19.1 51.2 46.4 31.7 57.2 39.8 49.4 15.6 18.9 35.6 23.8 23.8 27.3 15.7 15.6 25.6 57.7 22.7 21.3 32.4 9.8 26.8 61.8 45.6 8.5 44.9 25.2 29.0 50.1 26.8 37.0 41.0 41.5 19.0 37.9 17.8 48.0 21.6 31.0 42.5 10.3 49.3 36.2 19.2 87.0 49.2 38.9 45.6 44.4 60.0 29.1 31.8 33.3 13.9 27.7 17.5 11.4 55.5 23.1 23.7 13.6 23.6 8.4 19.5 14.7 8.3 12.1 7.5 8.0 7.7 11.1 8.6 10.6 9.5 16.3 8.9 10.6 9.3 8.8 11.3 10.2 5.9 16.3 8.3 8.3 9.3 10.0 12.2 9.4 9.5 8.5 9.5 9.2 8.7 8.7 8.9 10.6 12.8 11.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 16.0 13.7 0.0 0.0 8.1 12.9 0.0 70.7 13.1 0.0 25.4 34.4 0.0 12.7 14.1 4.6 0.0 0.0 0.0 38.2 39.9 10.1 0.0 14.3 5.1 17.5 0.0 0.0 24.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 32.0 0.0 0.0 0.0 0.0 25.2 0.0 0.0 1.8 0.0 0.0 35.6 3.6 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 83.5 7.6 43.3 0.0 0.0 L3MBTL1 "dJ138B7.3, DKFZp586P1522, KIAA0681, L3MBTL, ZC2HC3" ENSG00000185513 "L3MBTL histone methyl-lysine binding protein 1" Q9Y468 20 43489442-43550954 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 24.4;Oligodendrocyte precursor cells: 31.2;Oligodendrocytes: 25.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SuSa: 5.1" HPA059648 Supported "Nucleoplasm,Nuclear bodies,Midbody ring" Yes NA "Cluster 48: NK-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear bodies, Midbody ring" "HPA059648: " "unprognostic (2.32e-1)" "unprognostic (2.77e-1)" "unprognostic (5.66e-2)" "unprognostic (7.19e-3)" "unprognostic (1.28e-1)" "unprognostic (1.50e-2)" "unprognostic (7.65e-4)" "unprognostic (6.02e-2)" "unprognostic (6.00e-2)" "unprognostic (2.23e-2)" "unprognostic (1.15e-3)" "unprognostic (1.20e-2)" "unprognostic (1.44e-3)" "unprognostic (2.01e-1)" "unprognostic (1.65e-1)" "unprognostic (2.89e-1)" "unprognostic (1.56e-4)" 2.7 4.8 8.6 0.8 8.5 0.8 3.9 6.4 10.2 6.4 6.1 6.1 1.1 5.0 2.0 4.2 6.9 0.6 3.9 8.0 9.4 5.9 2.0 3.0 0.8 8.0 8.8 7.5 3.3 1.1 16.7 0.6 8.7 6.4 0.7 3.4 4.6 1.7 5.1 3.9 4.8 0.8 6.1 5.5 3.9 10.1 10.8 0.8 6.9 1.1 0.5 4.8 6.4 7.6 0.1 0.1 1.6 0.9 0.1 0.0 2.6 0.2 0.3 0.5 0.4 0.2 1.7 0.9 0.4 0.9 0.5 1.1 0.0 0.4 0.3 0.0 1.1 0.3 1.4 2.1 0.3 0.0 0.3 0.3 0.6 0.1 0.0 2.9 0.3 0.9 0.6 0.2 0.1 0.3 0.4 1.2 1.0 0.7 1.4 0.6 0.2 0.5 1.2 0.4 0.4 1.3 0.5 0.5 0.1 5.1 0.6 1.7 0.6 0.2 1.1 0.0 0.4 1.0 0.4 0.3 1.5 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.2 8.6 8.5 6.4 10.2 8.0 9.4 8.0 8.8 8.7 6.1 10.8 7.6 1.2 3.2 3.2 16.0 3.3 0.9 2.0 1.9 8.0 17.2 2.7 2.8 1.9 1.5 4.2 5.5 14.6 2.1 5.2 0.9 1.9 1.3 2.0 2.4 2.6 2.2 1.2 1.7 12.4 0.2 3.3 1.9 2.0 1.8 5.1 8.3 1.8 0.6 1.4 6.7 24.4 2.1 4.1 1.6 1.8 2.8 5.0 2.0 3.6 4.7 1.0 4.7 4.1 31.2 25.4 0.8 1.9 6.0 1.7 2.5 3.1 0.7 6.6 10.8 0.0 4.2 2.8 13.9 12.3 1.5 1.1 1.9 2.3 4.6 1.8 1.4 LAMP5 "BAD-LAMP, C20orf103, dJ1119D9.3, UNC-46" ENSG00000125869 "Lysosomal associated membrane protein family member 5" Q9UJQ1 20 9514358-9530524 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 96.6;retina: 29.6" "Cell type enhanced" "Detected in many" "dendritic cells: 78.4;Granulosa cells: 22.2;Horizontal cells: 60.6;Inhibitory neurons: 38.9;Theca cells: 23.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 15 "plasmacytoid DC: 141.3" "Lineage enriched" "Detected in many" 31 "dendritic cells: 141.3" "Cell line enhanced" "Detected in some" "Karpas-707: 469.4;SH-SY5Y: 86.4;THP-1: 169.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004802, HPA070765" Enhanced Uncertain "Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "Mitotic spindle, Centriolar satellite" "HPA004802: AB_10603682, HPA070765: AB_2686309" "unprognostic (2.78e-2)" "unprognostic (3.90e-3)" "unprognostic (5.73e-4)" "unprognostic (5.47e-2)" "unprognostic (7.89e-2)" "unprognostic (2.67e-1)" "unprognostic (3.80e-3)" "unprognostic (1.45e-1)" "unprognostic (1.54e-2)" "unprognostic (1.91e-1)" "unprognostic (1.94e-1)" "unprognostic (1.95e-1)" "prognostic unfavorable (6.46e-6)" "unprognostic (5.12e-3)" "unprognostic (3.74e-2)" "unprognostic (1.08e-2)" "unprognostic (4.49e-3)" 0.5 4.3 41.7 1.5 96.6 2.3 0.9 11.0 51.8 8.8 3.7 2.2 1.2 4.8 6.3 0.4 10.6 3.1 0.4 39.1 14.3 0.8 0.2 0.9 5.7 47.7 10.1 21.9 1.2 0.7 6.3 0.1 43.7 2.3 1.2 29.6 1.1 3.8 0.1 0.7 1.3 3.9 29.1 1.8 1.4 0.9 35.3 1.4 0.9 0.2 5.2 0.7 1.2 13.6 0.1 0.2 1.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 469.4 0.0 0.0 0.0 0.0 2.2 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.3 86.4 0.0 0.0 0.1 0.4 0.0 169.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 21.1 0.3 4.2 1.7 0.0 0.0 0.3 0.2 4.5 0.0 0.1 9.5 0.5 0.0 0.0 0.4 0.0 0.0 141.3 0.0 2.4 41.7 96.6 11.0 51.8 39.1 14.3 47.7 10.1 43.7 29.1 35.3 13.6 0.5 0.0 1.1 6.2 3.4 0.1 0.0 0.0 0.0 12.3 0.3 4.3 0.3 0.0 0.0 0.0 8.4 0.0 78.4 0.0 0.0 0.8 5.4 0.2 0.7 0.8 0.0 0.0 10.0 0.0 0.0 8.4 0.0 0.7 0.0 22.2 0.0 0.0 1.3 60.6 38.9 0.0 0.0 0.6 0.8 7.5 0.6 3.5 3.6 4.7 5.4 3.9 0.0 13.0 1.5 0.4 0.0 0.0 5.5 0.5 0.0 0.0 0.0 5.7 0.0 0.3 13.9 0.6 1.1 0.0 0.0 0.0 0.9 23.2 0.1 0.0 LAP3 "LAP, LAPEP, PEPS" ENSG00000002549 "Leucine aminopeptidase 3" P28838 4 17577198-17607972 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 230.6;Hofbauer cells: 262.1;Proximal tubular cells: 274.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029606, HPA029607" Enhanced Supported Nucleoplasm,Midbody,Cytosol Yes No 3500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Nucleoplasm, Midbody" "HPA029606: AB_10599288, HPA029607: AB_10611381" "unprognostic (2.10e-2)" "unprognostic (1.01e-1)" "unprognostic (6.95e-3)" "unprognostic (1.46e-1)" "unprognostic (1.26e-1)" "unprognostic (2.87e-1)" "unprognostic (2.16e-1)" "unprognostic (1.55e-1)" "unprognostic (5.33e-2)" "unprognostic (1.44e-3)" "unprognostic (2.61e-3)" "unprognostic (1.17e-1)" "unprognostic (4.29e-3)" "unprognostic (1.73e-1)" "unprognostic (3.28e-2)" "unprognostic (3.06e-1)" "unprognostic (8.79e-2)" 92.8 52.6 33.0 131.4 34.8 59.2 60.3 39.0 42.9 30.7 31.4 60.3 78.3 34.4 25.4 44.6 45.4 67.3 65.0 31.8 36.3 106.3 190.4 100.6 150.4 46.3 37.7 24.0 30.9 61.0 22.1 70.9 42.2 36.7 62.0 20.0 67.7 31.0 68.1 40.3 61.3 76.2 45.6 94.1 55.3 43.8 41.9 56.8 46.4 63.8 94.3 82.8 25.3 42.9 51.7 44.4 41.6 39.4 80.5 97.9 0.4 79.6 89.1 282.3 340.3 81.4 96.1 202.0 51.7 61.6 167.9 31.3 157.7 56.3 106.7 77.7 45.2 112.1 47.3 107.6 94.1 102.3 69.2 100.0 35.3 92.7 48.6 32.3 99.7 52.2 110.6 139.9 67.6 55.6 91.9 139.5 87.1 96.3 83.9 139.8 39.8 102.7 73.5 59.6 61.4 50.2 72.9 44.4 161.1 57.3 37.9 39.1 65.2 71.3 48.5 76.1 140.6 127.7 208.8 172.7 96.3 167.2 70.8 43.1 200.6 44.7 33.7 210.0 31.0 32.7 31.2 36.3 204.6 23.5 26.7 28.3 28.1 54.0 158.1 116.6 60.2 135.8 33.0 34.8 39.0 42.9 31.8 36.3 46.3 37.7 42.2 45.6 41.9 42.9 230.6 28.9 49.6 10.7 34.4 22.0 26.1 60.1 21.6 8.1 53.5 41.7 48.9 18.6 44.1 27.6 2.1 35.9 68.3 44.2 117.4 68.6 100.5 67.3 45.7 129.7 16.3 31.7 6.4 109.2 54.7 42.0 29.6 40.7 64.1 29.4 71.0 95.5 262.1 6.7 9.6 35.6 42.7 92.1 50.5 31.7 23.0 141.9 42.7 18.7 195.0 103.8 28.8 9.5 21.2 53.3 31.8 35.0 71.2 26.9 52.4 274.0 92.5 15.4 32.9 31.3 57.8 95.7 13.7 32.5 22.9 55.7 42.4 80.7 45.6 27.1 LARP6 "acheron, FLJ11196" ENSG00000166173 "La ribonucleoprotein 6, translational regulator" Q9BRS8 15 70829130-70854157 "Predicted intracellular proteins" "Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 429.0;Late spermatids: 259.8;Spermatocytes: 166.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-2197: 232.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020338, HPA049029" Approved Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Microtubules "Cytokinetic bridge" "HPA020338: AB_1844500, HPA049029: AB_2680604" "unprognostic (1.35e-3)" "unprognostic (1.95e-1)" "unprognostic (7.43e-2)" "unprognostic (2.63e-3)" "unprognostic (2.96e-2)" "unprognostic (4.70e-2)" "unprognostic (2.44e-2)" "unprognostic (2.80e-3)" "unprognostic (4.27e-2)" "unprognostic (2.87e-2)" "unprognostic (1.07e-1)" "unprognostic (1.28e-2)" "prognostic unfavorable (9.90e-5)" "unprognostic (4.51e-3)" "unprognostic (8.90e-2)" "unprognostic (2.13e-1)" "unprognostic (3.43e-1)" 51.4 9.8 42.8 6.5 69.8 0.1 44.0 56.9 65.5 27.5 22.8 18.5 2.1 22.8 28.4 7.9 29.0 10.9 43.4 44.5 52.0 27.9 10.6 17.9 2.3 57.8 56.6 30.4 10.9 19.6 23.6 7.7 56.4 26.1 4.0 11.8 19.5 14.1 17.6 14.0 10.3 12.1 46.8 2.6 26.9 9.6 55.9 5.1 40.8 26.1 1.5 21.1 31.0 90.4 42.3 44.2 14.1 28.3 70.2 77.9 0.1 127.7 99.0 67.4 71.2 12.9 12.0 0.0 50.9 69.9 65.4 22.7 32.0 11.2 66.4 0.4 78.3 0.2 37.6 12.0 127.1 0.2 0.2 49.0 45.6 67.9 107.5 70.6 22.2 15.4 0.1 0.6 30.4 7.3 0.3 0.3 14.9 0.0 113.9 0.2 50.6 0.3 22.0 35.9 8.4 18.5 42.5 0.5 93.1 21.7 2.3 2.4 29.6 27.4 109.6 232.0 107.5 0.2 0.3 0.4 116.9 0.0 14.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 42.8 69.8 56.9 65.5 44.5 52.0 57.8 56.6 56.4 46.8 55.9 90.4 32.3 0.0 1.1 2.9 0.1 18.1 47.7 20.4 9.6 41.4 15.4 18.3 22.2 24.3 11.8 12.9 2.1 0.5 1.0 0.3 54.8 59.4 429.0 24.6 31.8 24.5 12.0 0.0 10.8 25.1 0.8 87.5 4.1 8.4 0.0 7.5 11.4 15.3 1.2 25.2 11.8 1.5 10.2 0.6 13.3 259.8 73.3 3.2 19.6 7.5 0.1 28.5 0.0 5.5 105.9 62.9 0.0 45.9 0.5 61.9 0.0 100.9 16.8 4.8 19.7 28.3 34.8 166.8 11.0 1.4 8.9 0.4 1.9 5.3 0.6 37.7 LBX2 ENSG00000179528 "Ladybird homeobox 2" Q6XYB7 2 74497517-74503316 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 5.3;liver: 8.7;stomach 1: 3.2" "Cell type enhanced" "Detected in some" "Hepatocytes: 3.7;Proximal tubular cells: 7.5;Sertoli cells: 6.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 10.5;Hep G2: 22.1;SK-MEL-30: 10.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cerebellum: 1.9;olfactory bulb: 1.0" HPA044257 Uncertain Approved Nucleoplasm,Midbody Yes No "Cluster 14: Monocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Midbody "HPA044257: AB_2678880" "unprognostic (5.24e-2)" "unprognostic (7.97e-2)" "unprognostic (2.35e-5)" "unprognostic (8.22e-4)" "unprognostic (2.95e-1)" "unprognostic (2.94e-1)" "unprognostic (1.34e-2)" "unprognostic (1.34e-1)" "unprognostic (2.02e-1)" "unprognostic (2.76e-2)" "unprognostic (1.85e-1)" "unprognostic (3.25e-2)" "unprognostic (1.43e-5)" "unprognostic (5.77e-2)" "unprognostic (1.69e-1)" "unprognostic (1.78e-1)" "unprognostic (1.87e-2)" 1.3 0.3 0.3 0.4 0.3 0.4 0.6 0.9 0.4 0.4 0.0 1.1 5.3 0.3 0.2 0.2 0.2 0.4 0.3 0.1 0.2 1.3 8.7 0.5 0.4 0.5 0.2 0.1 0.7 0.1 0.0 0.5 0.5 0.3 0.1 0.1 0.5 0.3 0.4 0.9 4.8 0.2 0.1 1.1 3.2 0.1 0.4 0.0 0.3 0.0 0.1 0.3 0.2 1.3 4.4 1.6 0.0 0.1 2.0 1.5 7.1 0.3 0.2 0.4 0.4 10.5 6.2 0.2 1.7 0.8 0.6 1.7 0.0 0.3 0.0 9.0 1.8 4.7 0.7 22.1 1.4 0.3 3.0 1.9 1.6 1.6 0.3 0.2 1.8 0.1 3.1 2.2 0.3 2.3 0.1 0.7 0.4 1.7 0.2 0.4 0.4 0.2 0.2 1.4 0.2 1.1 2.6 0.4 10.1 0.1 0.2 0.3 4.1 1.5 6.6 8.1 0.2 2.9 2.3 0.2 1.5 0.8 4.8 0.5 1.5 0.1 0.3 0.8 0.2 0.0 0.1 0.4 0.8 0.0 0.1 0.2 0.6 1.1 2.2 0.2 0.0 0.7 0.3 0.3 0.9 0.4 0.1 0.2 0.5 0.2 0.5 0.1 0.4 1.3 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.7 0.5 0.7 1.5 0.5 1.8 0.0 0.3 0.5 0.9 0.0 0.6 0.0 0.4 0.5 1.0 2.4 0.4 0.0 0.6 0.5 1.3 1.1 0.2 0.0 0.0 1.4 3.7 1.1 0.0 0.0 0.2 0.0 0.6 0.3 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 0.0 2.4 7.5 0.7 0.0 6.6 0.0 0.9 0.4 0.1 0.3 0.1 0.5 0.5 0.2 1.0 0.1 LETM2 "FLJ25409, SLC55A2" ENSG00000165046 "Leucine zipper and EF-hand containing transmembrane protein 2" Q2VYF4 8 38386207-38409527 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 23.8" "Cell type enhanced" "Detected in many" "Early spermatids: 76.9;Late spermatids: 57.6;Pancreatic endocrine cells: 48.6;Spermatocytes: 54.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 21.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 21.5" "Cell line enhanced" "Detected in many" "HBEC3-KT: 25.2;hTERT-HME1: 26.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 24.0" HPA025032 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 78: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Nuclear bodies, Cytosol" "HPA025032: AB_1852808" "unprognostic (3.37e-2)" "unprognostic (2.73e-1)" "unprognostic (3.14e-1)" "unprognostic (2.05e-2)" "unprognostic (2.27e-4)" "unprognostic (3.20e-2)" "unprognostic (3.96e-2)" "unprognostic (1.43e-1)" "unprognostic (8.27e-2)" "unprognostic (3.80e-2)" "unprognostic (1.39e-1)" "unprognostic (1.35e-1)" "unprognostic (3.40e-2)" "unprognostic (4.09e-3)" "unprognostic (2.49e-1)" "unprognostic (1.16e-1)" "unprognostic (9.25e-2)" 1.2 1.0 3.4 1.1 3.6 5.3 0.7 5.7 4.9 1.6 2.9 0.7 0.8 1.4 1.1 1.1 1.4 1.2 0.8 3.2 2.8 2.3 0.7 2.0 1.3 2.3 2.9 2.1 0.7 1.6 1.3 1.8 3.1 1.1 0.8 4.2 0.4 0.8 0.2 1.1 0.5 0.6 2.0 1.6 2.7 23.8 2.6 2.4 1.0 0.3 1.4 1.9 0.6 4.2 21.2 4.5 3.0 2.9 2.3 7.0 2.5 7.5 9.2 10.6 6.2 1.5 8.3 2.8 16.5 1.5 3.1 2.2 5.9 25.2 11.7 1.2 2.9 3.2 2.3 4.2 2.7 0.7 2.8 1.7 7.2 11.7 26.9 5.9 10.7 3.4 2.6 3.9 9.3 4.2 7.5 1.8 0.8 1.6 18.2 2.9 4.8 1.6 16.8 1.1 2.4 2.3 2.5 0.4 0.9 1.8 2.4 1.2 20.0 3.3 22.5 7.4 1.7 2.6 1.6 2.0 5.6 3.3 2.5 1.3 4.1 0.7 0.9 1.6 2.0 1.5 0.9 1.5 1.7 1.8 1.7 1.7 21.5 1.4 5.0 0.7 5.2 1.3 3.4 3.6 5.7 4.9 3.2 2.8 2.3 2.9 3.1 2.0 2.6 4.2 3.0 3.2 6.4 2.3 10.3 0.5 13.9 7.6 6.8 6.6 2.1 3.3 1.8 4.3 3.2 5.5 6.2 2.6 10.1 1.4 1.9 4.0 76.9 21.8 7.1 4.2 0.0 0.8 3.6 20.5 7.9 5.0 16.8 20.5 9.5 1.1 1.4 0.0 1.4 6.7 7.3 1.9 2.0 2.2 2.3 57.6 2.1 3.6 1.8 1.0 2.0 3.6 1.0 1.5 1.6 48.6 0.1 1.5 4.5 2.9 0.3 3.0 4.9 8.4 0.0 4.5 3.3 54.8 3.3 2.5 0.9 8.1 9.1 1.5 1.3 4.5 LIAS LAS ENSG00000121897 "Lipoic acid synthetase" O43766 4 39459004-39485109 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 86.0;Late spermatids: 100.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018842, HPA019076" Approved Supported Approved Nucleoplasm,Mitochondria Yes No "Cluster 30: Non-specific - Translation" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Mitochondria "HPA018842: AB_1852864, HPA019076: AB_1852866" "unprognostic (3.61e-1)" "unprognostic (1.89e-1)" "unprognostic (8.44e-2)" "unprognostic (2.33e-1)" "unprognostic (4.87e-2)" "unprognostic (1.49e-1)" "unprognostic (8.31e-2)" "unprognostic (1.57e-1)" "unprognostic (4.19e-2)" "unprognostic (3.68e-2)" "unprognostic (2.46e-3)" "unprognostic (3.80e-2)" "prognostic favorable (4.11e-7)" "unprognostic (9.41e-3)" "unprognostic (2.35e-1)" "unprognostic (5.45e-2)" "unprognostic (6.98e-2)" 5.4 7.5 5.9 3.0 6.5 6.6 5.7 7.6 9.8 5.1 5.9 6.4 5.5 4.6 5.3 6.7 6.1 3.6 11.1 6.2 6.7 8.7 8.6 2.9 5.1 6.3 6.4 10.0 6.8 6.5 4.0 3.3 6.8 4.1 6.4 5.4 4.3 3.1 27.2 5.7 5.2 5.2 5.5 3.6 6.3 9.8 6.2 4.3 4.2 21.0 4.2 5.8 4.7 8.3 5.7 4.5 5.4 5.2 11.5 11.4 4.8 6.6 3.7 6.1 4.1 6.8 7.8 20.8 7.3 2.5 15.2 4.9 15.9 9.1 8.0 2.4 4.0 8.8 2.3 7.0 10.4 19.1 5.5 10.8 14.6 7.1 22.4 13.4 7.0 12.7 21.1 5.2 7.5 3.6 10.9 24.9 7.3 15.3 14.2 9.1 15.2 12.9 7.1 2.9 6.0 4.8 3.8 4.9 22.5 7.6 5.6 8.8 2.6 4.7 10.6 6.3 15.5 9.9 15.8 14.3 7.2 22.2 4.0 2.5 6.4 3.9 5.7 7.6 12.7 10.0 8.1 8.0 6.2 7.6 16.2 11.6 3.4 7.7 5.6 5.5 5.7 4.7 5.9 6.5 7.6 9.8 6.2 6.7 6.3 6.4 6.8 5.5 6.2 8.3 11.0 9.6 12.6 14.0 12.9 9.7 11.6 17.4 12.0 25.8 15.7 17.3 20.1 17.2 12.7 18.4 10.4 24.0 22.6 12.9 21.5 13.2 86.0 11.2 15.8 10.3 18.1 12.4 11.9 6.4 18.2 10.4 9.2 10.3 17.7 19.0 11.4 19.0 17.5 10.1 18.8 13.5 18.3 13.5 7.8 100.1 10.2 11.4 1.8 6.5 17.6 15.4 16.5 14.6 22.9 10.3 10.1 12.4 5.8 6.6 18.3 32.6 14.1 26.7 0.0 10.8 20.5 64.9 25.1 13.7 9.2 9.6 14.2 19.0 18.4 8.8 LIG1 ENSG00000105486 "DNA ligase 1" P18858 19 48115445-48170603 "Enzymes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, DNA replication" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 34.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037015, HPA041431, HPA048071" Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus, Vesicles" "CAB037015: , HPA041431: AB_2677476, HPA048071: AB_2680248" "unprognostic (1.83e-1)" "unprognostic (1.48e-3)" "unprognostic (6.45e-2)" "unprognostic (9.76e-2)" "unprognostic (9.47e-2)" "unprognostic (9.24e-3)" "unprognostic (1.17e-3)" "unprognostic (2.28e-1)" "unprognostic (6.03e-3)" "unprognostic (4.26e-1)" "unprognostic (1.78e-2)" "unprognostic (1.10e-3)" "prognostic unfavorable (5.75e-5)" "unprognostic (3.59e-2)" "unprognostic (4.09e-2)" "unprognostic (1.59e-2)" "unprognostic (1.55e-2)" 2.8 3.2 3.3 9.0 3.2 34.5 3.6 3.6 3.5 5.5 2.3 6.8 8.6 4.0 2.5 7.4 5.9 2.3 1.6 2.9 3.2 2.9 4.0 3.4 15.6 4.4 2.9 6.0 7.0 4.2 4.8 5.1 4.5 4.0 4.2 2.7 4.8 3.0 3.8 10.4 9.6 2.2 2.6 6.0 5.2 8.2 3.1 20.7 5.1 1.0 9.7 3.5 5.0 3.9 43.4 64.1 57.1 37.6 2.6 4.2 41.7 27.0 19.1 44.1 47.2 35.0 42.9 83.7 15.3 11.2 11.9 30.1 24.7 26.7 16.9 45.2 48.8 56.4 38.7 47.5 1.0 63.0 43.7 5.7 2.5 23.0 3.4 5.0 24.0 51.0 46.3 29.8 23.3 44.0 107.3 123.7 33.6 46.7 15.9 84.1 48.4 43.6 12.3 64.8 36.3 36.5 32.3 33.6 10.1 12.5 22.7 44.5 22.6 31.7 54.3 23.9 40.3 29.3 49.0 83.1 12.7 38.0 33.3 0.0 1.6 2.6 7.8 6.8 7.7 10.9 8.8 8.3 1.6 10.0 11.5 8.2 1.3 12.1 3.3 1.5 10.9 5.7 3.3 3.2 3.6 3.5 2.9 3.2 4.4 2.9 4.5 2.6 3.1 3.9 3.9 3.2 13.6 5.9 16.1 8.3 9.5 8.7 24.5 21.5 7.8 12.3 3.9 7.2 10.3 3.7 10.4 31.1 9.6 10.2 7.9 5.8 19.3 12.0 5.1 8.3 0.0 36.2 4.2 5.2 35.8 6.8 5.1 8.3 6.3 23.1 5.0 5.3 16.4 8.4 5.6 10.0 6.1 3.5 6.8 8.5 2.1 6.6 3.6 3.7 7.2 10.9 11.3 3.5 8.4 3.0 4.4 1.9 23.0 2.8 7.6 4.7 19.5 11.3 13.1 4.5 6.5 13.5 26.1 15.9 9.1 10.0 13.9 6.0 15.3 8.7 LIX1 "C5orf11, Lft" ENSG00000145721 "Limb and CNS expressed 1" Q8N485 5 97091867-97142753 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 32.4;retina: 42.6" "Cell type enriched" "Detected in some" 13 "Muller glia cells: 289.4" "Cancer enhanced" "Detected in many" "glioma: 13.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.2" "Lineage enriched" "Detected in single" 6 "B-cells: 2.2" "Group enriched" "Detected in some" 13 "RPTEC TERT1: 53.5;SuSa: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA058426 Uncertain Approved "Vesicles,Cytokinetic bridge,Cytosol" Yes NA "Cluster 37: B-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 5: Muller glia cells - Visual perception" Cytosol "Vesicles, Cytokinetic bridge" "HPA058426: AB_2683715" "unprognostic (3.18e-1)" "unprognostic (4.53e-2)" "unprognostic (9.46e-2)" "prognostic unfavorable (2.48e-4)" "unprognostic (8.96e-2)" "unprognostic (6.60e-2)" "unprognostic (1.34e-1)" "unprognostic (4.70e-1)" "unprognostic (7.63e-2)" "unprognostic (1.58e-2)" "unprognostic (3.52e-1)" "unprognostic (2.01e-1)" "unprognostic (4.88e-2)" "unprognostic (2.16e-1)" "unprognostic (1.26e-1)" "unprognostic (9.61e-2)" 0.0 0.3 24.0 0.2 22.3 0.3 0.0 24.7 16.2 0.0 7.1 0.6 0.1 0.1 0.1 0.1 0.1 0.1 0.1 26.6 30.7 3.1 0.0 0.0 0.5 31.1 32.4 0.0 0.0 0.0 1.5 0.4 24.7 1.5 0.3 42.6 0.0 5.8 0.0 0.1 0.2 0.2 32.2 0.1 0.4 0.1 26.1 0.0 4.6 0.0 0.0 0.0 0.0 29.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 53.5 0.0 0.1 0.0 0.0 0.0 0.0 31.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 24.0 22.3 24.7 16.2 26.6 30.7 31.1 32.4 24.7 32.2 26.1 29.1 0.0 0.0 0.0 21.2 1.3 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.7 0.0 0.1 12.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.5 0.0 0.0 1.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 3.3 1.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 289.4 0.0 0.5 1.4 0.0 0.0 0.0 0.1 0.1 0.0 2.3 0.0 9.4 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LLPH "C12orf31, hLLP, MGC14817" ENSG00000139233 "LLP homolog, long-term synaptic facilitation factor" Q9BRT6 12 66116555-66130750 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048920, HPA058786" Enhanced "Nucleoli,Mitotic chromosome" Yes No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoli "Mitotic chromosome" "HPA048920: AB_2680556, HPA058786: AB_2683820" "unprognostic (3.60e-3)" "unprognostic (4.94e-2)" "unprognostic (4.07e-2)" "unprognostic (3.03e-2)" "unprognostic (2.13e-1)" "unprognostic (4.31e-2)" "prognostic unfavorable (6.44e-7)" "unprognostic (7.15e-2)" "unprognostic (1.30e-2)" "unprognostic (8.49e-3)" "unprognostic (2.15e-2)" "unprognostic (1.07e-2)" "unprognostic (3.87e-2)" "unprognostic (9.65e-3)" "unprognostic (2.49e-2)" "unprognostic (3.37e-1)" "unprognostic (2.94e-2)" 21.6 34.4 12.3 24.4 13.5 50.3 18.6 12.7 16.0 13.2 11.2 20.1 19.2 15.2 18.6 19.5 13.2 14.7 23.2 12.8 13.7 20.9 21.2 15.5 26.3 13.5 14.3 17.6 17.2 17.0 10.7 17.5 13.7 15.3 20.3 7.4 14.5 14.1 29.7 13.8 18.2 19.4 13.0 18.2 19.1 22.1 13.5 22.1 17.3 25.3 25.6 27.3 14.0 14.2 77.0 61.1 36.4 44.2 42.6 40.8 44.5 87.0 56.4 63.9 53.6 52.8 31.0 87.0 70.6 58.6 50.7 63.6 57.2 52.9 85.7 78.4 48.8 94.5 41.7 47.3 49.8 162.5 61.8 41.9 53.6 53.7 58.3 50.1 56.6 44.1 81.5 60.9 76.1 81.3 74.1 110.4 77.9 61.6 63.0 61.9 67.2 62.7 63.3 90.8 36.3 45.1 57.0 58.3 97.4 38.0 77.4 89.5 60.5 48.3 71.3 60.9 80.4 45.7 77.6 130.2 65.4 76.0 76.8 34.3 32.0 35.5 27.8 38.0 32.0 29.2 32.3 30.6 31.3 27.5 27.4 29.2 43.8 27.4 48.4 27.0 38.9 28.8 12.3 13.5 12.7 16.0 12.8 13.7 13.5 14.3 13.7 13.0 13.5 14.2 34.2 12.8 33.9 2.9 47.6 27.1 53.9 86.3 30.1 15.9 24.5 28.4 25.1 41.5 64.3 31.3 4.2 66.3 49.4 34.1 66.5 68.3 63.3 40.5 45.4 32.5 13.8 33.4 5.0 71.3 70.4 34.8 35.7 46.6 89.4 61.2 35.7 60.2 64.2 21.9 4.4 31.1 85.5 50.4 26.5 17.0 43.8 45.6 35.6 3.7 84.1 30.8 59.8 3.0 5.8 96.3 43.3 30.1 27.3 46.3 44.0 86.5 35.8 15.2 26.3 29.7 36.8 126.6 48.6 30.6 30.5 72.7 43.8 126.4 36.1 60.6 LMO4 ENSG00000143013 "LIM domain only 4" P61968 1 87328880-87348923 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial stromal cells: 508.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "AN3-CA: 586.8;T-47d: 373.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022345, HPA045877, HPA061638" Approved Supported "Nucleoplasm,Midbody ring" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm "Midbody ring" "CAB022345: , HPA045877: AB_2679480, HPA061638: AB_2684572" "unprognostic (5.39e-2)" "unprognostic (4.62e-3)" "unprognostic (2.67e-2)" "unprognostic (4.33e-3)" "unprognostic (1.37e-1)" "unprognostic (2.05e-2)" "prognostic unfavorable (5.25e-4)" "unprognostic (3.97e-3)" "unprognostic (7.44e-2)" "prognostic favorable (1.47e-4)" "unprognostic (3.46e-2)" "unprognostic (6.82e-2)" "unprognostic (1.14e-2)" "unprognostic (2.86e-2)" "unprognostic (2.87e-2)" "prognostic favorable (1.42e-4)" "unprognostic (1.70e-1)" 49.0 16.3 102.1 28.6 116.5 21.9 34.7 79.8 173.7 51.7 70.8 44.7 26.7 43.2 39.4 50.9 32.4 45.5 42.2 117.4 82.9 42.7 33.3 38.2 29.5 82.1 78.9 39.6 25.5 22.9 31.6 63.9 80.1 56.4 31.6 34.5 87.4 81.0 47.6 39.7 43.1 30.3 79.4 38.7 90.7 28.0 83.2 23.5 33.8 25.5 87.8 38.8 54.0 100.6 55.1 42.3 32.3 586.8 96.6 113.9 81.8 48.4 38.3 44.9 49.8 104.3 34.0 127.5 60.3 57.2 72.4 44.7 13.1 33.8 44.5 68.6 32.4 116.5 87.2 32.3 92.9 63.6 151.2 60.2 76.4 70.0 39.8 80.9 30.8 48.7 26.8 109.8 24.5 22.3 1.8 41.3 118.1 58.6 39.3 72.8 45.0 28.5 56.1 206.7 26.5 1.7 195.3 28.7 149.6 61.1 373.3 171.8 20.1 208.9 39.0 50.6 161.7 99.7 70.6 28.8 26.1 13.8 30.7 30.5 9.1 19.5 7.8 11.6 9.0 10.1 6.9 8.0 6.9 6.9 1.8 4.4 15.0 22.4 11.5 10.3 2.1 5.1 102.1 116.5 79.8 173.7 117.4 82.9 82.1 78.9 80.1 79.4 83.2 100.6 103.5 44.8 24.1 50.9 88.6 98.4 49.3 105.6 245.3 226.2 170.0 191.5 72.4 153.0 78.1 36.8 73.0 322.8 116.5 50.0 62.6 74.2 2.1 106.5 508.1 65.6 31.1 48.1 204.4 127.6 363.3 149.0 159.6 131.5 307.4 19.5 78.1 85.7 74.0 111.0 37.5 80.6 14.2 138.4 73.2 7.5 95.1 76.1 65.8 22.5 74.6 82.7 83.4 52.8 25.8 107.2 29.9 235.5 174.6 49.3 90.3 56.8 31.0 35.9 32.9 80.6 175.5 4.4 97.9 200.3 92.9 256.0 77.9 61.7 64.9 37.5 LPIN2 KIAA0249 ENSG00000101577 "Lipin 2" Q92539 18 2916994-3013144 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transcription, Transcription regulation" Hydrolase "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 165.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 154.4;Granulosa cells: 323.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 7 "granulocytes: 23.4;NK-cells: 12.5;T-cells: 12.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015223, HPA017857, HPA030550" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Cytosol "Plasma membrane, Actin filaments" "CAB015223: , HPA017857: AB_1852904, HPA030550: AB_2673519" "unprognostic (7.03e-2)" "unprognostic (1.05e-1)" "unprognostic (2.88e-1)" "unprognostic (1.51e-3)" "unprognostic (1.20e-1)" "prognostic favorable (8.01e-4)" "unprognostic (9.85e-3)" "unprognostic (1.89e-2)" "unprognostic (1.03e-2)" "unprognostic (3.44e-3)" "unprognostic (3.19e-1)" "unprognostic (1.94e-1)" "unprognostic (3.15e-3)" "unprognostic (4.66e-2)" "unprognostic (2.21e-1)" "unprognostic (2.49e-1)" "unprognostic (7.11e-2)" 9.7 9.3 17.9 21.2 19.9 19.8 9.8 14.6 17.4 9.7 16.6 13.9 62.8 9.8 6.7 10.0 9.5 25.7 7.2 16.1 24.2 26.4 165.8 21.2 24.3 22.7 22.0 13.2 16.4 13.5 10.9 15.7 24.2 9.0 12.5 10.7 7.4 8.0 2.7 3.6 39.9 9.6 15.6 20.3 28.1 22.0 28.8 18.9 12.1 3.0 19.2 9.9 6.0 14.3 8.7 12.0 17.1 6.6 31.7 27.4 10.5 17.4 22.8 18.9 16.9 16.7 7.1 5.4 10.8 30.2 30.2 0.2 13.8 6.3 13.2 11.2 2.7 13.3 10.0 19.4 27.2 11.2 17.0 27.4 4.6 18.5 17.2 28.2 23.4 14.8 12.8 3.5 28.2 7.2 15.0 12.0 5.7 13.7 13.1 26.7 14.0 23.2 17.6 20.0 14.4 10.2 18.4 9.1 6.8 10.7 0.0 18.0 31.2 25.3 28.7 31.7 14.6 5.0 7.9 12.3 22.1 12.2 8.1 8.7 2.4 7.8 11.8 1.5 12.1 1.0 9.2 7.2 1.0 1.7 9.1 6.3 23.4 12.5 0.8 1.5 9.2 3.2 17.9 19.9 14.6 17.4 16.1 24.2 22.7 22.0 24.2 15.6 28.8 14.3 17.7 67.3 44.0 55.2 20.4 5.6 9.8 8.5 5.7 35.7 12.1 11.2 11.2 154.4 23.9 38.6 14.6 25.2 41.9 45.3 17.6 11.8 3.3 48.2 33.3 18.9 14.9 138.1 26.3 19.0 11.3 25.4 103.0 64.4 12.6 323.0 19.2 131.1 23.1 116.1 65.6 36.8 16.2 26.8 8.9 11.0 22.7 31.1 8.8 79.6 31.2 16.7 59.8 37.7 21.0 22.2 21.6 31.2 16.1 21.2 92.4 54.9 17.1 16.7 6.6 16.6 20.1 26.5 73.0 0.6 2.0 49.5 58.9 20.3 14.0 14.1 LRRC17 "H_RG318M05.3, P37NB" ENSG00000128606 "Leucine rich repeat containing 17" Q8N6Y2 7 102913000-102945111 "Predicted secreted proteins" Osteogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 76.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 31.3;Granulosa cells: 68.6;Leydig cells: 101.9;Peritubular cells: 31.6;Sertoli cells: 65.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 94 "eosinophil: 9.9" "Lineage enriched" "Detected in single" 94 "granulocytes: 9.9" "Cell line enriched" "Detected in many" 5 "LHCN-M2: 1237.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA073458 Approved "Vesicles,Cytokinetic bridge" "Secreted in other tissues" Yes NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Cytokinetic bridge" "HPA073458: " "unprognostic (1.77e-1)" "unprognostic (7.73e-2)" "unprognostic (4.79e-2)" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (2.48e-1)" "unprognostic (4.46e-1)" "unprognostic (1.18e-1)" "unprognostic (9.76e-4)" "unprognostic (6.09e-3)" "unprognostic (2.26e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (4.12e-6)" "unprognostic (8.57e-3)" "unprognostic (4.48e-2)" "unprognostic (6.17e-2)" "prognostic unfavorable (6.30e-4)" 8.1 2.4 1.6 1.1 1.7 0.2 12.9 1.6 2.4 22.5 1.7 2.7 1.6 15.7 12.1 6.0 17.3 27.4 13.2 1.7 1.6 2.8 3.5 3.2 2.1 1.6 1.7 76.2 2.3 2.0 2.4 0.6 1.5 5.6 3.3 1.8 2.7 3.2 2.1 3.0 2.3 6.0 1.6 3.3 6.9 5.0 2.3 6.2 3.8 2.8 1.0 4.4 5.8 1.6 0.0 0.0 58.8 0.5 6.0 29.4 0.1 1.6 18.2 0.6 2.8 0.0 0.2 0.0 3.4 1.5 7.3 0.1 0.0 0.0 4.3 0.0 1.4 0.1 0.0 0.1 8.3 0.5 0.2 28.1 0.7 21.5 0.0 141.1 140.9 0.6 0.0 0.1 1237.5 0.0 0.1 0.4 3.1 0.1 0.1 0.1 244.0 0.2 0.2 0.1 1.3 1.3 0.1 0.0 0.1 0.1 0.0 1.7 11.8 0.2 1.5 15.2 2.3 1.1 0.4 0.0 0.3 0.0 0.3 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.7 1.6 2.4 1.7 1.6 1.6 1.7 1.5 1.6 2.3 1.6 3.6 0.0 1.1 4.6 0.2 0.9 0.2 0.9 0.0 3.7 0.7 0.8 1.1 0.0 0.5 1.8 2.1 0.3 0.3 0.0 0.0 1.7 3.5 2.7 15.3 4.4 0.0 0.0 6.9 0.4 0.2 31.3 1.1 4.6 1.3 68.6 6.1 0.5 0.4 0.0 8.7 0.1 2.0 0.0 2.7 2.9 101.9 0.5 5.4 10.3 0.6 0.6 0.0 2.5 5.3 0.2 0.3 31.6 0.0 0.3 0.1 0.3 0.1 2.2 65.7 16.1 17.8 0.6 0.5 0.4 0.6 0.0 0.9 6.6 0.2 0.2 LRRC34 MGC27085 ENSG00000171757 "Leucine rich repeat containing 34" Q8IZ02 3 169793003-169812986 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 12.8" "Cell type enhanced" "Detected in many" "Early spermatids: 137.9;Respiratory ciliated cells: 129.6;Spermatocytes: 104.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HEL: 8.1;HL-60: 8.9;JURKAT: 7.1;NTERA-2: 7.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA035747 Approved Approved "Cell Junctions,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 37: B-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 36: HEL - Hemostasis" "Cluster 49: Ciliated cells - Cilium organization" "Cell Junctions, Microtubules" "Cytokinetic bridge, Mitotic spindle" "HPA035747: AB_10670120" "unprognostic (1.04e-2)" "unprognostic (5.71e-2)" "unprognostic (5.67e-2)" "unprognostic (5.64e-2)" "unprognostic (9.74e-3)" "unprognostic (5.46e-2)" "unprognostic (9.74e-2)" "unprognostic (8.24e-2)" "unprognostic (6.39e-3)" "unprognostic (2.57e-1)" "unprognostic (6.05e-2)" "unprognostic (1.23e-1)" "unprognostic (8.39e-2)" "unprognostic (1.16e-2)" "unprognostic (3.48e-1)" "unprognostic (3.37e-1)" "unprognostic (2.79e-1)" 1.5 0.4 1.6 0.6 2.1 1.4 1.1 1.6 2.7 0.9 2.8 0.5 0.2 0.7 0.3 0.2 5.5 0.3 1.1 1.2 2.1 0.7 0.2 1.0 0.8 2.1 2.5 0.8 0.2 0.3 2.8 0.2 2.2 0.6 0.1 5.6 0.3 0.7 0.4 0.5 0.4 0.2 2.1 0.7 0.4 12.8 1.9 0.6 0.9 0.4 0.3 0.4 0.4 1.8 2.3 0.4 0.5 0.0 0.9 3.0 0.0 0.9 1.9 2.4 2.1 0.1 0.0 1.5 0.1 0.6 3.1 0.0 1.8 0.0 0.8 0.4 5.6 8.1 0.2 0.0 0.6 8.9 1.8 0.9 0.4 0.8 0.0 0.1 1.6 7.1 0.2 0.0 0.9 0.0 0.8 1.1 7.7 0.0 2.6 4.0 0.0 0.4 2.1 0.2 4.0 3.1 0.5 0.3 0.0 0.2 0.0 4.2 0.5 0.4 0.0 0.3 0.1 0.1 0.1 1.9 3.5 0.1 2.2 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.1 1.6 2.1 1.6 2.7 1.2 2.1 2.1 2.5 2.2 2.1 1.9 1.8 3.9 3.2 2.6 8.5 1.5 0.4 0.9 5.3 0.0 6.9 0.4 0.9 3.2 0.0 12.9 5.5 37.5 0.2 1.6 0.1 1.9 0.5 137.9 33.8 5.8 3.0 4.2 4.2 15.1 0.2 0.3 5.0 0.5 1.0 1.3 1.0 10.4 0.3 2.4 11.8 12.5 0.4 6.1 0.8 1.2 36.3 10.5 1.2 0.0 3.7 3.8 7.4 0.0 9.5 3.6 0.3 0.0 10.5 0.7 0.4 0.0 3.6 129.6 18.8 0.0 3.6 3.7 104.4 9.2 0.1 0.3 0.5 0.9 1.9 0.2 0.4 LRRN4 "C20orf75, dJ1056H1.1, NLRR4" ENSG00000125872 "Leucine rich repeat neuronal 4" Q8WUT4 20 6040546-6054060 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 8.3;lung: 9.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Alveolar cells type 2: 3.9;Collecting duct cells: 1.8;Ductal cells: 3.8;Proximal tubular cells: 2.4" "Group enriched" "Detected in many" 7 "lung cancer: 4.6;ovarian cancer: 3.6;renal cancer: 11.7" "Region enhanced" "Detected in some" "basal ganglia: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "RPTEC TERT1: 79.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA075974 Uncertain "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 73000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" "Nucleoli, Nucleoli rim, Mitotic chromosome" "HPA075974: AB_2686770" "unprognostic (6.16e-2)" "unprognostic (1.69e-3)" "unprognostic (2.40e-3)" "unprognostic (9.04e-3)" "unprognostic (5.95e-2)" "unprognostic (1.32e-2)" "unprognostic (2.59e-1)" "unprognostic (8.94e-2)" "unprognostic (2.73e-1)" "unprognostic (2.44e-2)" "unprognostic (2.79e-2)" "unprognostic (4.83e-3)" "unprognostic (1.15e-3)" "unprognostic (2.33e-2)" "unprognostic (6.88e-2)" "unprognostic (2.31e-1)" "unprognostic (9.84e-3)" 8.3 0.0 0.3 0.0 2.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.2 0.6 2.2 0.1 9.7 0.0 0.2 0.2 0.4 1.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 5.3 1.4 0.0 3.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.6 79.6 0.0 0.3 0.1 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.1 0.0 1.0 0.2 0.6 0.2 0.2 0.0 0.1 0.7 0.0 0.0 9.6 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 3.8 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 2.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 LYRM1 A211C6.1 ENSG00000102897 "LYR motif containing 1" O43325 16 20899868-20925006 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 188.1;Late spermatids: 464.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 154.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 154.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059840 Supported Nucleoplasm,Midbody Yes No "Cluster 2: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm Midbody "HPA059840: AB_2684137" "unprognostic (4.44e-2)" "unprognostic (1.03e-1)" "unprognostic (1.66e-2)" "prognostic favorable (7.48e-7)" "unprognostic (3.04e-1)" "unprognostic (1.10e-1)" "unprognostic (3.47e-1)" "unprognostic (8.60e-2)" "unprognostic (1.20e-1)" "unprognostic (1.04e-2)" "unprognostic (1.49e-2)" "unprognostic (3.39e-1)" "prognostic unfavorable (4.80e-4)" "unprognostic (1.57e-1)" "unprognostic (6.18e-2)" "unprognostic (3.86e-1)" "prognostic favorable (9.50e-4)" 37.8 31.1 26.7 16.4 27.2 24.2 30.0 28.7 31.4 30.4 31.6 32.0 13.8 27.6 35.2 18.7 34.4 16.2 50.8 27.1 28.3 51.8 95.8 18.8 24.2 28.1 27.7 34.0 27.3 33.5 21.2 13.6 28.7 29.1 20.4 26.5 16.2 26.8 42.3 19.2 18.0 22.6 27.3 16.9 27.9 37.6 27.7 25.1 22.8 34.1 21.9 34.8 23.0 28.5 33.2 29.7 30.3 25.9 74.1 64.0 9.6 27.9 39.3 14.8 21.7 42.8 39.2 22.6 92.2 31.5 21.6 21.6 14.1 25.5 25.6 41.6 19.8 10.1 8.3 112.1 56.6 35.9 20.4 45.0 24.5 40.0 98.6 41.4 58.5 37.3 23.2 39.6 59.0 43.5 39.1 26.3 34.3 46.5 17.2 47.8 18.4 30.8 56.3 15.1 29.8 27.7 16.6 26.3 45.1 18.5 27.5 19.5 16.0 21.4 15.8 35.1 19.6 35.1 51.2 38.5 59.7 35.6 20.1 154.9 16.7 59.3 19.7 21.8 28.2 29.5 29.8 24.2 14.3 24.8 24.3 24.1 63.8 22.1 25.9 17.9 33.0 24.5 26.7 27.2 28.7 31.4 27.1 28.3 28.1 27.7 28.7 27.3 27.7 28.5 32.5 19.2 18.9 9.1 29.9 21.0 57.6 26.8 25.6 28.9 41.2 39.4 55.1 27.1 17.2 23.9 14.6 29.1 24.6 9.6 76.3 41.3 188.1 24.2 12.9 35.8 30.0 8.4 10.6 44.2 10.6 30.8 21.9 15.9 15.8 20.5 15.0 53.9 16.5 15.2 14.1 15.0 28.5 16.4 14.5 464.6 28.9 16.2 17.8 4.7 45.7 48.0 22.6 9.5 11.2 30.2 14.6 38.0 15.8 41.6 19.2 125.4 25.4 34.0 13.1 25.8 26.3 112.5 27.5 18.2 20.9 14.9 22.9 16.3 24.5 56.7 LYST "CHS, CHS1" ENSG00000143669 "Lysosomal trafficking regulator" Q99698 1 235661041-235883640 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Phagocytosis, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 31.3;retina: 27.9" "Cell type enhanced" "Detected in all" "monocytes: 277.4" "Cancer enhanced" "Detected in all" "melanoma: 11.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 12.2" "Group enriched" "Detected in many" 5 "granulocytes: 12.2;monocytes: 6.1" "Cell line enhanced" "Detected in many" "HDLM-2: 30.8;SK-MEL-30: 27.1;THP-1: 99.5;U-937: 38.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053366, HPA055725" Supported "Nucleoplasm,Plasma membrane,Centriolar satellite" Yes No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Plasma membrane, Centriolar satellite" "HPA053366: AB_2682129, HPA055725: AB_2682898" "unprognostic (1.56e-2)" "unprognostic (1.54e-1)" "unprognostic (9.92e-2)" "unprognostic (8.85e-2)" "unprognostic (1.96e-2)" "unprognostic (4.32e-2)" "unprognostic (4.11e-2)" "unprognostic (7.79e-2)" "unprognostic (4.08e-2)" "unprognostic (1.95e-1)" "unprognostic (1.55e-1)" "unprognostic (9.31e-2)" "prognostic unfavorable (5.27e-5)" "unprognostic (1.59e-1)" "unprognostic (1.54e-1)" "unprognostic (6.29e-2)" "unprognostic (1.99e-1)" 5.2 2.7 2.0 8.5 2.7 31.3 6.4 10.1 3.3 7.1 9.1 4.5 3.0 4.3 2.7 4.2 3.9 5.1 2.2 2.0 2.5 3.6 5.5 5.5 7.5 2.2 2.6 4.5 2.2 6.2 1.8 4.6 2.5 3.4 4.3 27.9 4.3 3.3 1.7 9.7 3.3 4.4 1.1 10.8 7.7 6.1 3.3 25.7 6.4 3.8 6.5 5.7 5.2 3.4 8.6 1.9 0.9 2.0 12.7 14.4 1.3 3.1 12.5 3.3 3.1 0.0 2.3 1.1 1.2 6.8 7.7 4.1 1.2 1.6 2.9 30.8 2.7 2.8 1.9 0.6 2.3 4.2 3.7 4.8 7.8 4.0 10.0 4.8 2.8 1.3 0.2 1.7 2.6 0.4 5.3 8.7 0.2 1.6 0.9 0.4 1.2 0.0 9.2 9.2 5.4 1.1 3.4 0.2 27.1 1.0 1.2 99.5 5.8 2.4 1.1 2.8 2.8 2.1 0.1 0.2 4.1 38.0 7.0 0.4 2.9 5.7 0.6 3.4 0.8 1.0 0.2 0.7 1.7 1.4 0.2 0.4 12.2 1.7 6.1 0.2 0.2 0.7 2.0 2.7 10.1 3.3 2.0 2.5 2.2 2.6 2.5 1.1 3.3 3.4 66.3 19.2 41.1 71.2 70.9 71.0 89.8 14.6 18.8 67.4 17.6 15.6 11.6 15.7 28.4 11.0 93.8 6.7 77.3 25.0 11.7 6.6 24.6 22.6 23.8 51.2 9.6 21.0 151.5 12.3 5.0 27.0 41.3 22.4 112.5 9.4 26.0 15.4 31.9 52.2 155.9 14.3 28.5 65.6 81.3 17.7 28.0 111.4 120.9 159.3 277.4 25.6 88.6 112.1 81.6 39.6 24.2 21.8 37.3 56.0 12.7 10.9 26.7 162.5 13.1 31.2 22.7 93.3 28.0 18.7 65.1 8.8 71.3 13.6 7.6 98.5 MAD2L1BP "CMT2, dJ261G23.1, KIAA0110" ENSG00000124688 "MAD2L1 binding protein" Q15013 6 43629540-43640941 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 221.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028729 Supported "Nucleoplasm,Nuclear membrane,Nucleoli" Yes No "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 21: OE19 - Mitochondria" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "Nuclear membrane, Nucleoli" "HPA028729: AB_2672752" "unprognostic (2.60e-1)" "unprognostic (2.06e-1)" "unprognostic (3.92e-2)" "unprognostic (6.97e-2)" "unprognostic (6.91e-2)" "unprognostic (6.92e-2)" "unprognostic (5.74e-3)" "unprognostic (2.67e-3)" "unprognostic (3.60e-1)" "unprognostic (7.18e-2)" "unprognostic (1.71e-1)" "unprognostic (6.64e-2)" "unprognostic (4.61e-2)" "unprognostic (1.18e-1)" "unprognostic (3.34e-1)" "unprognostic (1.16e-1)" "unprognostic (3.25e-3)" 13.3 16.2 13.6 14.1 13.8 53.5 17.3 14.1 15.8 14.6 15.4 25.9 23.6 12.4 17.3 17.6 16.7 14.4 25.4 14.3 14.9 17.5 21.9 14.9 21.7 13.8 13.2 13.0 16.7 21.1 12.6 14.0 14.2 14.4 27.7 15.2 22.8 13.5 28.5 13.2 18.8 14.5 13.6 17.4 19.3 20.4 14.3 29.3 15.6 44.6 26.6 21.4 10.6 13.8 53.9 24.4 37.7 42.2 32.1 34.7 22.7 31.7 50.9 68.5 63.8 50.3 21.4 41.6 17.6 37.3 62.2 34.4 59.2 43.9 52.6 38.5 46.0 51.5 26.1 43.8 34.6 30.6 29.9 35.3 53.0 51.1 31.0 34.5 52.2 32.8 67.2 21.8 48.4 50.6 27.4 56.5 23.3 221.1 31.3 31.3 29.3 39.4 48.9 42.5 44.7 45.3 22.8 34.5 152.2 28.6 40.6 80.3 28.7 36.5 30.7 24.4 51.3 27.7 25.8 99.0 33.2 51.3 41.0 105.4 41.4 49.4 46.3 42.8 46.5 52.6 54.7 51.4 52.7 47.9 56.5 51.2 35.2 55.6 41.3 34.9 78.9 43.6 13.6 13.8 14.1 15.8 14.3 14.9 13.8 13.2 14.2 13.6 14.3 13.8 11.6 25.6 12.7 3.3 18.2 14.4 20.5 44.9 17.6 12.8 11.6 9.3 10.8 15.7 32.5 3.7 12.5 21.1 11.1 30.7 27.4 28.0 47.0 13.2 8.6 12.5 17.4 20.6 3.0 21.2 21.5 12.0 14.3 10.8 31.6 7.8 11.4 12.7 17.6 10.1 3.2 17.1 32.6 10.4 8.6 36.5 12.2 19.6 28.4 1.9 17.3 13.9 11.3 3.0 5.0 24.7 29.5 12.0 11.1 11.5 28.2 21.2 21.1 15.1 26.3 8.3 13.4 26.4 18.3 12.6 9.7 6.2 14.8 11.9 23.4 27.2 MAEA "EMP, GID9, HLC-10, p44EMLP" ENSG00000090316 "Macrophage erythroblast attacher, E3 ubiquitin ligase" Q7L5Y9 4 1289887-1340147 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Erythrocyte maturation, Ubl conjugation pathway" "Actin-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036886, HPA058185" Approved Enhanced Nucleoplasm Yes No "Cluster 5: Granulocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA036886: , HPA058185: AB_2683633" "unprognostic (2.70e-2)" "unprognostic (1.52e-1)" "unprognostic (1.78e-2)" "unprognostic (1.11e-1)" "unprognostic (2.03e-2)" "prognostic favorable (5.34e-4)" "unprognostic (3.10e-3)" "unprognostic (3.89e-2)" "unprognostic (1.78e-1)" "unprognostic (2.50e-1)" "unprognostic (6.94e-3)" "unprognostic (4.65e-3)" "prognostic favorable (1.90e-4)" "unprognostic (1.17e-2)" "unprognostic (2.49e-1)" "unprognostic (1.97e-1)" "unprognostic (4.51e-2)" 28.5 44.2 21.9 23.5 21.3 18.3 28.8 19.8 24.0 32.6 25.9 39.7 33.5 34.4 10.9 46.7 29.2 17.5 38.6 21.1 27.2 40.9 32.3 24.0 24.3 25.7 23.0 34.9 35.4 30.7 38.9 17.2 26.3 29.2 14.2 8.8 35.7 21.5 37.1 41.2 35.7 14.9 18.1 40.0 37.1 26.8 23.2 20.7 33.9 19.2 15.7 30.7 33.5 20.0 58.1 66.9 47.6 47.7 31.5 31.1 61.4 57.4 30.6 47.1 42.2 70.5 73.5 52.5 43.6 42.4 85.5 42.0 46.1 72.2 19.1 42.4 52.2 49.2 74.1 68.1 37.1 55.8 50.9 38.8 38.6 37.8 23.6 31.8 38.0 50.4 70.4 41.6 41.3 61.5 84.2 86.5 62.2 63.4 72.9 81.0 38.1 47.8 50.3 68.2 84.7 57.8 51.1 39.3 41.5 26.3 71.5 48.4 52.8 85.9 36.0 39.0 96.1 50.5 83.4 58.1 59.0 51.3 48.2 74.9 49.9 70.9 59.2 52.6 83.5 47.6 47.1 56.4 47.1 38.1 41.4 42.5 117.9 45.5 77.3 33.0 59.8 59.1 21.9 21.3 19.8 24.0 21.1 27.2 25.7 23.0 26.3 18.1 23.2 20.0 22.0 19.2 25.0 28.4 21.6 18.7 15.7 33.9 8.0 28.1 22.5 25.3 35.5 14.3 24.3 16.5 20.9 48.2 29.7 41.2 46.9 43.4 8.0 21.9 25.2 24.4 20.4 26.3 19.6 30.3 46.4 25.0 25.5 25.0 10.8 30.4 19.6 15.0 39.6 21.9 23.2 33.1 30.5 29.2 15.9 9.8 35.4 23.2 28.4 14.0 46.3 22.3 28.8 22.6 20.0 40.3 31.3 37.2 23.5 22.7 30.4 36.4 17.9 19.1 13.1 24.9 27.9 36.6 44.0 19.3 19.9 95.2 29.7 59.6 38.1 21.8 MAFB KRML ENSG00000204103 "MAF bZIP transcription factor B" Q9Y5Q3 20 40685848-40689236 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 273.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 264.0;Hofbauer cells: 377.6;Kupffer cells: 672.8;Macrophages: 456.7;Squamous epithelial cells: 361.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 88.3;non-classical monocyte: 121.4" "Lineage enriched" "Detected in many" 15 "monocytes: 121.4" "Cell line enhanced" "Detected in some" "HSkMC: 28.6;hTCEpi: 61.2;SCLC-21H: 16.7;SiHa: 15.6;U-138 MG: 16.4;U-2197: 24.4;U-87 MG: 16.0" "Low region specificity" "Detected in many" HPA005653 Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" Yes NA "Cluster 51: Monocytes - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "Nucleoli, Golgi apparatus, Cytosol" "HPA005653: AB_1079293" "unprognostic (1.55e-1)" "unprognostic (1.17e-2)" "unprognostic (1.16e-3)" "prognostic unfavorable (5.64e-4)" "unprognostic (9.16e-2)" "unprognostic (3.92e-2)" "unprognostic (1.10e-1)" "unprognostic (2.10e-1)" "unprognostic (2.57e-2)" "unprognostic (6.09e-2)" "unprognostic (5.45e-3)" "unprognostic (9.92e-2)" "unprognostic (3.95e-2)" "unprognostic (1.05e-1)" "unprognostic (3.21e-3)" "unprognostic (3.49e-2)" "unprognostic (2.30e-2)" 35.3 13.8 4.8 37.3 4.9 59.2 27.3 4.4 10.5 16.5 6.9 9.5 7.8 9.3 5.4 33.0 11.3 24.4 10.7 3.7 5.7 17.5 29.3 20.9 27.8 14.3 6.3 6.8 15.8 273.1 3.1 13.2 7.2 8.3 7.2 0.6 18.3 4.7 15.8 85.3 13.2 14.2 9.0 96.3 11.0 3.9 13.1 6.7 50.1 16.7 12.7 13.9 21.9 15.8 0.0 0.0 0.0 2.6 1.5 0.2 0.4 0.3 0.1 0.3 0.1 0.4 0.2 0.0 1.9 0.4 0.0 3.8 0.0 0.0 0.0 0.0 1.4 0.0 1.2 0.2 0.9 0.0 0.1 28.6 61.2 0.2 2.1 0.0 0.4 0.0 0.0 0.0 0.1 0.9 0.3 7.4 2.6 6.2 0.0 0.0 0.0 0.0 0.5 0.4 16.7 1.4 15.6 1.5 3.9 5.4 1.5 0.3 0.5 16.4 0.3 24.4 0.0 0.0 0.0 0.0 16.0 0.6 0.0 0.4 24.3 0.0 0.0 88.3 0.0 0.0 0.0 0.1 7.9 0.1 0.0 0.0 2.1 0.0 121.4 0.1 0.0 10.6 4.8 4.9 4.4 10.5 3.7 5.7 14.3 6.3 7.2 9.0 13.1 15.8 70.0 22.4 37.9 1.6 7.8 68.6 50.5 17.1 264.0 12.0 112.2 217.8 208.9 7.2 16.8 51.5 25.0 9.8 7.6 117.1 1.9 2.3 0.8 15.7 64.4 39.1 57.7 4.0 0.8 3.4 2.8 172.7 49.5 27.6 10.8 0.9 34.6 36.1 377.6 3.3 25.4 50.7 6.1 672.8 91.7 2.8 29.5 456.7 21.4 6.5 65.3 21.9 3.1 2.0 1.3 4.9 30.9 24.5 5.6 29.7 89.5 1.3 2.4 8.3 13.1 160.6 102.4 0.8 1.7 361.5 88.2 12.4 9.5 114.6 39.0 19.2 MAGEC2 "CT10, HCA587, MAGE-C2, MAGEE1" ENSG00000046774 "MAGE family member C2" Q9UBF1 X 142202342-142205290 "Cancer-related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Tumor antigen" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 197 "testis: 19.6" "Group enriched" "Detected in some" 13 "Spermatocytes: 84.6;Spermatogonia: 91.5" "Cancer enhanced" "Detected in many" "melanoma: 19.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "K-562: 87.3;U-266/84: 99.8" HPA062230 Enhanced Supported Nucleoplasm,Cytosol Yes NA "Cluster 36: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA062230: AB_2684718" "unprognostic (1.25e-1)" "unprognostic (5.68e-2)" "unprognostic (3.99e-1)" "unprognostic (2.82e-1)" "unprognostic (1.04e-1)" "unprognostic (4.00e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 87.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.9 3.7 0.0 0.0 0.0 0.2 5.7 0.9 11.3 0.0 0.1 99.8 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 84.6 91.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MAGEE1 "DAMAGE, KIAA1587" ENSG00000198934 "MAGE family member E1" Q9HCI5 X 76427710-76431342 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 11.2;Excitatory neurons: 12.2;Horizontal cells: 28.6;Inhibitory neurons: 12.2;Sertoli cells: 19.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 7.8" "Low region specificity" "Detected in all" HPA003047 Approved Approved "Cytokinetic bridge,Cytosol" Yes No "Cluster 39: Non-specific - mRNA processing" "Cluster 10: Brain - Neuronal signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" Cytosol "Cytokinetic bridge" "HPA003047: AB_1079298" "unprognostic (9.30e-2)" "unprognostic (2.14e-1)" "unprognostic (2.24e-1)" "unprognostic (1.65e-3)" "unprognostic (1.76e-1)" "unprognostic (3.94e-2)" "unprognostic (5.61e-3)" "unprognostic (8.72e-3)" "unprognostic (2.41e-3)" "unprognostic (1.43e-1)" "prognostic favorable (3.95e-4)" "unprognostic (7.91e-2)" "prognostic favorable (6.86e-6)" "unprognostic (4.60e-3)" "unprognostic (2.71e-1)" "unprognostic (6.03e-3)" "unprognostic (5.99e-3)" 1.6 3.2 10.0 1.6 10.2 0.3 1.6 3.0 20.6 2.8 0.0 2.2 0.5 3.3 1.7 1.0 2.5 1.1 2.2 12.1 17.0 2.1 0.3 1.3 2.5 7.7 5.1 4.7 2.6 6.1 6.0 0.0 7.9 3.2 0.9 6.4 1.7 4.0 1.1 1.8 1.8 2.6 1.0 2.7 1.6 0.4 9.8 2.9 2.1 0.9 1.9 2.1 1.7 6.7 0.2 3.8 3.9 7.5 2.7 1.5 3.4 2.9 2.9 2.4 1.3 0.8 0.6 0.8 1.4 2.5 7.8 2.9 5.8 5.4 1.9 1.9 0.1 0.0 0.0 2.5 0.5 1.5 0.5 1.1 2.4 0.6 0.6 0.1 0.9 4.2 0.3 0.0 3.6 0.5 4.3 0.2 4.7 0.0 5.8 3.4 2.9 0.0 3.1 0.0 0.0 2.0 0.0 0.4 0.6 3.9 1.7 0.1 0.5 3.6 4.5 3.8 0.0 0.0 0.0 0.6 1.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.1 0.2 0.5 0.0 0.2 0.3 0.3 0.0 0.3 0.0 0.0 0.0 0.1 10.0 10.2 3.0 20.6 12.1 17.0 7.7 5.1 7.9 1.0 9.8 6.7 0.8 3.2 2.6 3.3 1.7 0.5 0.7 1.2 1.2 11.2 0.9 1.9 1.9 1.5 1.1 1.8 4.2 0.2 1.4 0.3 1.9 1.4 0.0 0.4 1.3 2.4 0.0 0.4 12.2 1.5 0.4 1.3 1.1 0.4 1.3 1.5 1.8 0.2 0.1 28.6 12.2 0.4 0.0 0.3 0.0 0.1 1.5 0.1 0.0 3.7 0.1 5.5 2.1 5.5 5.0 0.7 0.0 4.5 0.3 0.3 0.0 1.3 0.3 5.0 19.7 2.7 3.6 0.3 0.2 0.6 0.1 0.1 2.5 0.8 0.1 0.2 MAGIX "FLJ21687, JM10, PDZX" ENSG00000269313 "MAGI family member, X-linked" Q9H6Y5 X 49162564-49168483 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 19.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 46.9;Hepatocytes: 35.0;Proximal tubular cells: 44.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 5.5;RT4: 12.8;SK-BR-3: 5.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007390, HPA035302" Uncertain Approved "Nucleoplasm,Mitotic chromosome" Yes NA "Cluster 17: Basophils - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" Nucleoplasm "Mitotic chromosome" "HPA007390: , HPA035302: AB_10603015" "unprognostic (1.11e-1)" "unprognostic (1.34e-2)" "unprognostic (6.24e-2)" "unprognostic (1.08e-1)" "unprognostic (2.55e-3)" "unprognostic (2.64e-6)" "unprognostic (6.75e-2)" "unprognostic (1.91e-3)" "unprognostic (3.38e-1)" "unprognostic (1.55e-3)" "unprognostic (1.16e-1)" "unprognostic (2.33e-2)" "prognostic favorable (6.91e-9)" "unprognostic (4.35e-2)" "unprognostic (2.70e-1)" "unprognostic (1.73e-1)" "prognostic favorable (2.10e-4)" 1.3 2.1 3.9 0.7 3.6 1.4 1.8 9.5 4.3 2.4 7.9 3.4 1.7 1.8 1.2 4.3 4.0 1.3 9.9 3.9 3.9 9.7 19.1 2.8 0.4 4.2 4.2 1.0 13.9 3.7 5.9 0.5 4.2 5.1 1.0 1.1 10.0 2.8 2.1 2.7 1.5 0.3 3.5 1.2 12.4 0.7 4.0 0.6 7.0 0.5 0.3 2.8 2.1 3.7 0.3 1.9 0.4 0.5 0.5 0.1 1.4 0.3 0.3 0.3 0.3 1.1 5.5 0.5 0.5 0.6 0.7 1.2 0.3 1.3 0.0 1.6 1.8 2.4 3.4 0.6 0.2 0.6 4.7 0.5 0.2 0.4 0.1 0.6 0.4 0.8 0.3 2.0 0.4 0.7 0.5 1.7 0.5 1.5 1.0 0.3 0.1 1.0 1.0 12.8 2.4 0.5 1.1 5.7 0.6 0.3 4.5 0.5 0.2 0.6 1.4 0.5 0.4 1.3 0.7 0.4 2.3 0.8 1.8 3.1 1.1 2.0 0.1 1.0 0.4 0.6 0.5 0.0 0.7 0.5 0.3 0.5 4.2 0.7 1.1 1.4 0.1 0.6 3.9 3.6 9.5 4.3 3.9 3.9 4.2 4.2 4.2 3.5 4.0 3.7 1.6 3.2 5.4 1.0 2.8 3.2 10.3 5.6 4.6 8.0 18.7 10.4 8.5 11.5 7.0 12.9 2.1 2.1 3.9 33.7 46.9 13.1 0.2 24.7 2.5 2.0 17.5 0.4 1.2 20.8 4.1 2.4 28.5 16.0 0.0 0.8 4.2 35.0 5.1 8.4 1.1 23.4 2.0 3.2 5.7 0.0 0.6 5.7 1.8 0.0 4.8 8.3 0.0 1.0 1.3 8.9 30.7 0.4 5.2 5.8 15.2 44.3 20.4 9.7 0.0 6.9 3.8 3.0 2.7 8.0 4.4 3.8 3.9 1.7 15.3 9.9 MAPK4 "Erk3-related, Erk4, PRKM4" ENSG00000141639 "Mitogen-activated protein kinase 4" P31152 18 50560087-50731826 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 81.9;parathyroid gland: 51.0" "Cell type enhanced" "Detected in some" "Astrocytes: 202.7;Excitatory neurons: 105.2;Inhibitory neurons: 58.5;Late spermatids: 66.4;Muller glia cells: 62.6" "Cancer enriched" "Detected in many" 4 "glioma: 15.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.3;HeLa: 3.3;NTERA-2: 2.2;SCLC-21H: 11.6;SH-SY5Y: 2.8;SK-MEL-30: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007461 Approved "Nucleoplasm,Golgi apparatus,Midbody" Yes NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Golgi apparatus" Midbody "HPA007461: AB_1079308" "unprognostic (4.12e-2)" "unprognostic (3.24e-2)" "unprognostic (3.60e-1)" "unprognostic (1.42e-3)" "unprognostic (5.17e-2)" "unprognostic (1.84e-2)" "unprognostic (6.32e-2)" "unprognostic (2.08e-2)" "unprognostic (8.24e-2)" "unprognostic (1.61e-1)" "unprognostic (4.38e-3)" "unprognostic (2.16e-1)" "unprognostic (3.44e-7)" "unprognostic (1.96e-4)" "unprognostic (5.99e-4)" "unprognostic (2.31e-2)" "unprognostic (1.82e-1)" 0.9 26.8 56.5 0.2 79.9 0.0 0.8 56.4 46.0 1.5 28.0 6.8 0.6 0.8 3.1 2.3 1.5 1.8 22.1 41.6 57.5 3.3 4.5 2.3 0.0 65.4 70.0 2.9 1.4 51.0 17.8 2.6 56.7 5.0 0.8 22.6 0.9 9.8 1.5 1.3 1.6 1.8 48.8 0.1 2.1 2.4 81.9 7.3 6.2 1.5 0.0 4.6 1.3 38.7 0.0 0.0 1.0 0.6 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 1.1 1.1 3.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.7 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 11.6 2.8 0.0 0.8 1.9 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 56.5 79.9 56.4 46.0 41.6 57.5 65.4 70.0 56.7 48.8 81.9 38.7 0.4 9.6 0.0 202.7 0.0 0.0 0.4 0.0 0.0 11.4 0.9 1.1 22.9 1.5 0.0 0.0 0.0 4.6 0.0 0.0 5.9 0.9 30.1 0.0 0.0 0.3 0.0 0.0 105.2 0.0 0.3 1.0 0.0 0.0 0.0 0.7 0.0 1.0 0.4 5.0 58.5 0.0 0.0 0.0 0.0 66.4 0.9 0.1 0.0 7.5 0.0 62.6 0.0 18.6 1.9 0.4 0.0 1.5 0.0 0.7 0.0 0.2 0.0 1.0 0.0 1.0 0.7 0.8 0.6 0.0 0.0 1.8 0.0 0.4 0.0 0.1 MATK "CHK, CTK, DKFZp434N1212, HHYLTK, HYL, HYLTK, Lsk, MGC1708, MGC2101" ENSG00000007264 "Megakaryocyte-associated tyrosine kinase" P42679 19 3777970-3802129 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.5;brain: 41.9" "Cell type enhanced" "Detected in many" "dendritic cells: 177.0;Hofbauer cells: 57.4;NK-cells: 422.2;T-cells: 99.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 76.8" "Group enriched" "Detected in many" 57 "NK-cells: 76.8;T-cells: 46.2" "Cell line enhanced" "Detected in some" "HL-60: 108.3;HMC-1: 30.9;K-562: 48.9;MCF7: 34.4;NB-4: 74.8;SCLC-21H: 30.9;THP-1: 27.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004847, HPA066547" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 48: NK-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 63: NK-cells & T-cells - Immune response" Microtubules "Cytokinetic bridge, Mitotic spindle, Centriolar satellite, Cytosol" "HPA004847: AB_1079316, HPA066547: " "prognostic favorable (5.27e-4)" "unprognostic (1.28e-2)" "unprognostic (1.84e-1)" "unprognostic (3.54e-2)" "unprognostic (3.36e-1)" "unprognostic (3.39e-2)" "unprognostic (9.50e-2)" "unprognostic (1.23e-1)" "unprognostic (7.91e-2)" "unprognostic (3.19e-3)" "unprognostic (2.07e-2)" "unprognostic (4.51e-2)" "unprognostic (1.16e-2)" "unprognostic (7.59e-2)" "unprognostic (1.66e-1)" "unprognostic (2.26e-1)" "unprognostic (2.33e-2)" 4.7 1.3 18.3 6.6 21.3 20.5 2.5 2.9 41.9 1.1 1.6 2.1 6.6 0.9 0.1 2.1 4.0 4.4 1.4 25.9 8.7 2.4 3.2 9.9 9.4 10.4 11.0 0.7 1.2 0.7 2.7 1.0 8.8 1.3 1.1 2.2 3.2 0.7 0.8 1.9 6.2 0.8 4.7 16.5 4.0 3.1 14.1 3.8 1.6 0.2 4.0 1.6 1.1 23.6 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.5 0.0 0.2 1.7 0.0 1.0 10.6 13.8 0.4 0.0 0.0 18.1 12.0 1.5 2.9 0.0 108.3 30.9 0.1 0.0 0.2 0.1 0.0 0.0 1.2 48.9 0.1 0.0 34.4 0.3 74.8 8.4 9.0 0.3 0.0 0.1 0.0 0.0 0.0 30.9 0.1 0.1 0.1 0.1 0.9 0.0 27.4 3.3 0.0 0.6 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 46.2 0.0 31.3 0.0 5.7 29.3 0.8 0.9 2.7 16.4 1.0 76.8 0.2 0.3 0.4 7.6 18.3 21.3 2.9 41.9 25.9 8.7 10.4 11.0 8.8 4.7 14.1 23.6 1.4 0.0 1.1 0.3 11.1 0.4 0.1 0.0 0.0 1.4 4.9 7.2 1.3 0.0 0.0 0.0 12.5 0.3 177.0 0.3 0.0 0.0 2.0 0.2 0.5 1.9 7.1 28.6 17.7 0.0 0.5 0.8 11.7 0.5 44.5 0.1 8.6 1.1 57.4 0.0 8.3 0.3 0.0 6.0 14.6 5.1 0.0 11.5 1.8 4.7 3.0 1.3 422.2 2.0 1.6 0.0 1.1 0.0 17.1 0.1 0.3 0.2 0.7 2.0 0.0 0.5 1.2 0.4 4.5 1.3 1.1 0.3 99.7 0.0 1.1 0.0 MBD5 "FLJ11113, KIAA1461" ENSG00000204406 "Methyl-CpG binding domain protein 5" Q9P267 2 148021011-148516971 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 317.4;Excitatory neurons: 510.1;Inhibitory neurons: 456.0;Microglial cells: 288.6;Oligodendrocyte precursor cells: 604.2;Oligodendrocytes: 438.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035964 Supported Nucleoplasm,Midbody Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Midbody" "HPA035964: AB_2674891" "unprognostic (1.10e-2)" "unprognostic (1.02e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (3.72e-4)" "unprognostic (5.81e-2)" "unprognostic (2.12e-1)" "unprognostic (2.22e-2)" "unprognostic (1.65e-1)" "unprognostic (9.86e-2)" "unprognostic (7.72e-2)" "unprognostic (2.00e-1)" "unprognostic (1.94e-1)" "unprognostic (2.39e-2)" "unprognostic (9.12e-2)" "unprognostic (1.12e-1)" "unprognostic (6.59e-2)" "unprognostic (1.82e-1)" 2.5 3.2 3.7 2.2 4.3 2.0 2.3 7.2 5.1 3.1 0.5 5.2 1.8 3.2 1.6 2.6 2.2 3.2 2.8 3.9 3.1 3.4 2.0 2.3 2.4 2.2 2.2 3.7 1.7 4.1 3.8 3.0 2.1 3.0 1.9 5.7 1.8 2.5 2.8 1.9 2.3 2.7 2.0 2.6 2.7 3.1 3.3 4.2 3.4 3.0 2.2 3.7 2.2 4.1 1.1 1.1 4.4 4.1 3.5 3.6 2.9 4.0 3.9 3.1 2.3 2.8 2.9 1.9 0.9 3.4 1.7 0.8 3.1 5.1 4.1 1.6 1.6 3.5 2.8 1.5 2.0 0.6 0.6 2.9 4.1 4.5 3.3 5.0 4.1 2.7 1.9 3.6 4.8 2.7 1.5 2.7 2.2 2.5 1.7 1.6 1.2 0.8 3.2 3.8 2.9 3.5 3.2 1.6 3.0 3.2 2.3 3.4 2.8 3.7 1.8 0.6 1.9 2.4 1.1 1.5 4.8 1.6 3.6 0.8 0.1 0.5 0.3 0.1 0.2 0.2 0.3 0.3 0.2 0.2 0.3 0.4 0.2 0.2 0.3 0.3 0.1 0.1 3.7 4.3 7.2 5.1 3.9 3.1 2.2 2.2 2.1 2.0 3.3 4.1 27.3 16.0 13.7 317.4 23.4 3.8 11.9 4.1 10.8 24.7 16.5 15.0 10.5 11.5 14.8 12.9 37.5 7.3 23.8 5.0 3.9 18.6 94.5 14.8 25.8 15.2 11.5 36.6 510.1 15.7 9.8 15.5 12.2 18.0 3.8 35.9 15.0 8.4 7.0 13.5 456.0 4.9 6.1 16.9 3.3 37.6 18.0 15.1 0.0 288.6 13.6 8.1 24.7 604.2 438.3 20.4 4.6 10.5 22.8 7.8 9.4 14.0 8.5 17.4 6.6 16.5 16.8 15.7 9.4 10.4 3.3 8.5 27.7 23.7 5.8 12.6 MCL1 "BCL2L3, Mcl-1" ENSG00000143384 "MCL1 apoptosis regulator, BCL2 family member" Q07820 1 150560895-150579738 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 685.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 106.3" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 12 "U-698: 4726.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002781, HPA008455, HPA031125, CAB068195" Enhanced Enhanced Mitochondria Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Mitochondria "CAB002781: , CAB068195: AB_2665695, HPA008455: AB_1079334, HPA031125: AB_10602026" "unprognostic (3.82e-2)" "unprognostic (8.79e-2)" "unprognostic (9.15e-2)" "unprognostic (2.05e-2)" "unprognostic (1.34e-1)" "unprognostic (3.91e-2)" "unprognostic (3.16e-2)" "unprognostic (2.43e-2)" "unprognostic (1.29e-1)" "unprognostic (8.60e-2)" "unprognostic (1.57e-2)" "unprognostic (1.65e-2)" "prognostic unfavorable (7.16e-4)" "unprognostic (3.22e-2)" "unprognostic (1.94e-1)" "unprognostic (4.87e-2)" "unprognostic (4.46e-2)" 297.8 149.2 72.9 264.9 75.0 685.1 175.0 77.0 84.2 143.4 85.0 137.1 99.4 98.5 41.8 199.3 190.7 278.8 139.1 65.3 81.5 125.2 404.6 237.1 161.2 86.4 77.8 105.3 161.7 89.2 82.8 146.9 79.4 96.3 120.1 90.1 124.7 56.4 153.8 189.2 133.6 171.4 80.6 171.5 167.0 41.3 91.4 128.9 133.3 160.1 157.1 302.6 124.6 75.8 140.2 74.8 131.9 73.3 262.9 262.2 175.8 164.8 174.5 173.0 139.4 91.9 112.3 184.9 102.2 120.2 80.3 187.7 101.7 203.3 166.7 154.8 68.3 76.4 109.9 106.2 204.7 130.6 151.3 147.3 221.3 170.6 330.0 159.5 192.7 49.4 168.1 225.3 234.2 160.3 64.6 80.7 242.0 122.9 131.9 94.7 111.1 85.9 195.2 103.7 95.9 134.2 125.6 135.9 232.4 191.2 100.4 195.2 251.6 109.2 119.4 55.5 212.8 310.2 409.5 4726.7 189.5 95.1 141.9 23.3 19.8 51.8 15.0 17.4 17.4 12.6 19.0 16.6 16.6 14.0 22.8 17.6 106.3 10.6 16.2 9.4 30.1 11.2 72.9 75.0 77.0 84.2 65.3 81.5 86.4 77.8 79.4 80.6 91.4 75.8 366.0 198.7 295.5 12.4 339.2 489.2 394.7 142.6 434.2 38.7 339.3 229.9 84.8 228.8 148.8 33.1 60.5 108.6 398.5 491.8 41.1 196.4 209.2 187.5 310.8 241.9 259.6 61.8 6.5 174.7 203.4 278.4 228.3 365.7 343.8 209.0 229.2 218.8 262.7 11.8 5.5 309.0 107.8 453.6 930.9 347.0 72.7 614.2 273.9 30.0 250.6 101.2 94.7 10.1 6.8 183.4 345.1 60.9 831.8 293.4 233.1 68.9 110.3 78.0 78.9 350.3 217.4 47.4 35.4 372.2 572.0 270.4 499.8 126.0 205.7 401.1 MCM10 "CNA43, DNA43, PRO2249" ENSG00000065328 "Minichromosome maintenance 10 replication initiation factor" Q7L590 10 13161558-13211110 "Predicted intracellular proteins" "DNA damage, DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 9.2;lymphoid tissue: 8.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 11.8;Erythroid cells: 23.5;Extravillous trophoblasts: 20.9;Plasma cells: 15.3;Spermatocytes: 15.8;Spermatogonia: 12.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045899, HPA071952" Approved Supported Nucleoplasm,Nucleoli Yes Yes "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli" "HPA045899: AB_10960529, HPA071952: AB_2686477" "unprognostic (9.76e-3)" "unprognostic (1.60e-1)" "unprognostic (2.31e-1)" "unprognostic (2.29e-3)" "unprognostic (1.41e-1)" "unprognostic (6.58e-3)" "unprognostic (1.78e-8)" "unprognostic (2.42e-3)" "unprognostic (3.51e-2)" "unprognostic (6.26e-2)" "unprognostic (2.78e-4)" "unprognostic (7.81e-2)" "unprognostic (0.00e+0)" "unprognostic (8.87e-2)" "unprognostic (1.29e-1)" "unprognostic (9.73e-2)" "unprognostic (1.05e-1)" 1.2 0.1 0.0 3.3 0.1 9.2 0.8 0.1 0.2 0.4 0.1 1.7 1.5 0.4 0.1 1.9 0.2 0.2 0.1 0.0 0.0 0.1 0.7 0.3 4.8 0.0 0.1 0.2 0.1 0.2 0.1 2.1 0.1 0.1 2.2 0.1 0.3 0.0 0.5 1.1 1.2 0.8 0.0 1.0 0.8 1.5 0.2 8.1 0.3 0.1 4.5 0.6 0.6 0.1 38.0 42.0 48.6 36.9 1.6 2.9 21.2 38.7 5.9 42.7 44.0 41.3 26.4 56.7 17.1 9.9 15.7 43.3 69.0 22.8 39.2 29.7 32.9 70.9 17.6 27.7 0.0 36.6 30.8 0.6 0.8 43.3 4.0 3.5 14.0 45.0 85.2 37.6 23.4 34.0 87.7 15.7 28.9 36.3 10.3 68.3 43.0 34.6 9.8 13.7 9.7 36.6 31.3 22.0 5.9 25.2 27.7 24.9 8.6 27.0 50.3 41.0 42.4 11.7 49.0 74.3 17.2 39.6 21.5 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.9 0.3 0.1 0.1 0.7 0.4 0.1 0.1 0.0 0.4 0.4 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 1.7 0.0 0.0 0.0 1.8 1.7 0.4 0.8 0.0 0.0 0.8 0.5 2.4 0.0 0.8 0.0 0.0 11.8 0.8 2.4 0.0 0.4 1.0 0.3 1.2 1.4 0.0 23.5 0.4 0.2 20.9 1.8 1.1 1.0 0.0 7.2 0.0 0.2 5.3 0.0 0.4 1.2 2.0 0.6 0.4 1.3 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.1 0.4 15.3 0.2 0.2 0.0 0.0 0.0 0.0 0.4 6.4 15.8 12.9 3.6 0.4 3.4 1.2 0.8 3.1 0.4 MCM2 "BM28, CCNL1, cdc19, CDCL1, D3S3194, DFNA70, KIAA0030" ENSG00000073111 "Minichromosome maintenance complex component 2" P49736 3 127598410-127622436 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 67.7;lymphoid tissue: 37.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 63.3;Erythroid cells: 65.6;Extravillous trophoblasts: 28.8;Spermatogonia: 25.9;Syncytiotrophoblasts: 33.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "CAB000303, HPA031450, HPA031495, HPA031496" Enhanced Enhanced Nucleoplasm Yes Yes 120000 "Cluster 43: B-cells - Humoral immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB000303: AB_322519, HPA031450: , HPA031495: AB_2673904, HPA031496: AB_2673905" "unprognostic (2.43e-1)" "prognostic favorable (4.66e-4)" "unprognostic (4.44e-2)" "unprognostic (3.12e-3)" "unprognostic (1.68e-1)" "unprognostic (2.25e-2)" "prognostic unfavorable (1.51e-7)" "unprognostic (8.43e-3)" "unprognostic (1.92e-2)" "unprognostic (1.79e-1)" "unprognostic (1.41e-3)" "unprognostic (1.21e-2)" "unprognostic (1.16e-2)" "unprognostic (8.16e-3)" "unprognostic (1.56e-1)" "unprognostic (3.29e-2)" "unprognostic (2.82e-1)" 3.1 3.4 2.0 16.4 1.9 67.7 6.2 2.5 1.9 5.3 0.6 9.2 8.1 5.0 2.4 11.0 7.6 2.5 6.4 1.9 1.8 3.4 6.3 3.4 26.8 2.3 1.9 6.4 3.0 3.7 2.4 17.0 2.6 5.0 10.2 3.5 4.7 2.8 9.4 10.6 8.6 5.3 2.0 9.6 5.7 12.3 2.0 37.6 4.8 5.8 26.0 4.2 5.4 2.4 133.6 110.3 122.4 102.1 7.0 14.4 110.5 65.2 42.3 129.9 146.9 177.7 84.7 136.0 65.2 32.3 113.6 105.6 204.8 76.1 79.1 127.2 127.1 227.4 134.8 131.1 4.4 214.3 102.4 8.2 8.4 86.1 13.1 15.3 40.6 160.7 116.0 123.7 47.4 169.0 229.0 156.2 172.5 108.3 90.7 242.4 165.1 203.3 26.9 97.9 143.0 106.8 175.8 48.9 16.7 45.7 111.9 165.3 20.3 104.2 87.9 128.4 91.7 127.1 163.5 362.6 73.2 159.7 41.0 0.0 0.6 0.3 4.4 1.4 5.5 9.7 3.9 5.4 2.9 8.1 3.6 4.7 0.9 6.5 0.4 3.7 11.2 3.5 2.0 1.9 2.5 1.9 1.9 1.8 2.3 1.9 2.6 2.0 2.0 2.4 1.2 3.2 2.0 0.7 8.5 4.6 2.6 4.6 2.2 2.5 4.1 5.3 8.3 0.0 3.9 0.0 0.0 63.3 1.8 4.8 0.0 5.3 0.9 5.2 3.5 2.9 3.6 65.6 0.3 1.9 28.8 4.2 6.6 4.8 1.3 18.8 1.4 1.7 18.2 0.0 0.4 8.2 0.0 1.6 3.2 0.7 1.8 2.7 1.8 0.0 9.2 2.1 0.0 0.0 0.7 2.1 1.7 1.5 20.5 0.8 1.1 0.8 7.4 2.1 0.0 2.6 4.1 8.1 25.9 7.1 3.0 33.5 6.3 3.8 13.8 2.3 MCM5 CDC46 ENSG00000100297 "Minichromosome maintenance complex component 5" P33992 22 35400134-35425431 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 138.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 147.8;Erythroid cells: 96.6;monocytes: 137.7;Syncytiotrophoblasts: 82.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000101, HPA000845, HPA052880" Enhanced Enhanced Nucleoplasm Yes Yes 44000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB000101: AB_2235163, HPA000845: AB_1079338, HPA052880: AB_2681979" "unprognostic (6.71e-2)" "prognostic favorable (2.81e-6)" "unprognostic (5.29e-3)" "unprognostic (7.94e-2)" "unprognostic (1.83e-2)" "unprognostic (1.46e-2)" "prognostic unfavorable (1.78e-4)" "prognostic unfavorable (3.95e-4)" "unprognostic (1.29e-1)" "unprognostic (3.34e-2)" "unprognostic (1.37e-1)" "unprognostic (8.07e-2)" "prognostic unfavorable (3.58e-5)" "unprognostic (3.26e-2)" "unprognostic (1.01e-1)" "unprognostic (1.77e-3)" "unprognostic (1.53e-1)" 15.2 7.1 5.8 49.1 10.4 138.7 14.4 8.3 7.4 14.5 5.8 20.2 19.6 16.3 3.3 25.1 13.7 9.6 8.9 5.8 7.0 9.1 14.9 14.8 70.1 10.3 7.7 25.6 12.6 10.3 5.3 25.2 9.6 10.2 16.7 2.3 13.9 9.6 13.3 17.6 28.3 12.2 8.1 47.3 17.9 20.6 9.0 58.9 12.1 8.0 53.6 12.7 15.6 12.3 213.0 147.5 115.7 118.8 11.0 22.2 100.6 138.1 71.2 199.4 188.3 98.9 102.4 137.9 78.8 70.5 83.6 103.8 116.0 108.3 64.4 112.7 212.6 198.3 141.5 203.7 3.9 414.0 172.4 12.3 9.7 120.0 32.4 18.4 88.7 124.5 124.0 201.2 76.9 172.7 341.8 137.9 154.9 143.4 86.7 379.6 164.8 173.0 39.4 120.1 88.2 94.8 188.3 75.4 41.8 60.9 78.8 155.6 54.1 201.3 153.1 127.2 145.4 111.9 150.2 265.2 130.9 153.5 157.6 66.5 59.8 43.4 49.5 69.6 35.8 127.5 43.1 53.1 77.8 106.1 34.0 39.0 28.4 65.5 81.2 88.8 96.6 77.1 5.8 10.4 8.3 7.4 5.8 7.0 10.3 7.7 9.6 8.1 9.0 12.3 8.1 6.4 7.3 1.3 49.5 10.6 13.6 12.1 8.6 1.5 9.2 10.8 3.5 8.6 6.0 7.3 0.0 147.8 30.4 12.0 5.9 19.8 2.8 6.2 4.1 11.8 3.5 96.6 0.3 12.7 77.1 11.2 18.8 9.0 15.2 65.7 13.2 5.3 53.1 1.7 0.4 16.6 4.1 24.0 29.4 5.1 10.8 28.4 7.2 7.5 137.7 5.7 13.4 3.0 6.0 11.0 8.6 6.0 49.3 4.0 6.5 5.7 4.8 3.7 19.7 8.8 14.5 16.1 58.8 14.9 6.3 82.2 19.4 8.5 34.6 9.8 MED26 "CRSP7, CRSP70" ENSG00000105085 "Mediator complex subunit 26" O95402 19 16574907-16629062 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 35.9" "Cell type enhanced" "Detected in many" "Early spermatids: 65.4;Late spermatids: 67.4;Spermatocytes: 54.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057997, HPA071835" Enhanced Approved Nucleoplasm,Vesicles,Cytosol Yes No "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Vesicles, Cytosol" "HPA057997: AB_2732618, HPA071835: AB_2686455" "unprognostic (2.02e-2)" "prognostic favorable (2.46e-4)" "unprognostic (2.47e-2)" "unprognostic (2.57e-3)" "unprognostic (1.42e-1)" "unprognostic (3.60e-3)" "unprognostic (5.03e-2)" "unprognostic (3.77e-2)" "unprognostic (1.34e-2)" "unprognostic (1.17e-2)" "unprognostic (2.99e-3)" "unprognostic (2.60e-2)" "prognostic unfavorable (5.50e-5)" "unprognostic (9.43e-3)" "unprognostic (1.64e-1)" "unprognostic (5.14e-2)" "unprognostic (5.98e-3)" 4.5 3.8 4.4 3.8 4.0 11.0 4.1 5.1 4.7 4.0 4.0 4.1 2.4 4.3 1.8 5.2 3.2 2.3 3.2 5.0 5.1 2.8 3.7 4.0 4.9 5.2 4.7 4.7 3.9 3.5 3.6 3.2 4.7 4.2 1.9 2.0 4.5 2.4 6.9 6.4 3.6 2.5 3.6 4.7 3.6 35.9 4.5 4.4 3.1 3.2 4.6 3.9 4.6 4.2 11.1 4.2 3.8 8.3 4.8 3.8 11.1 6.3 4.4 6.7 6.0 6.3 6.5 17.6 6.5 4.0 2.1 8.2 5.9 6.3 4.6 13.0 12.2 6.9 4.2 5.1 4.7 7.9 6.3 4.6 6.1 5.7 5.9 4.0 3.6 9.1 11.5 20.7 4.2 11.1 8.4 7.4 9.0 5.2 13.4 8.7 5.8 19.3 4.0 4.3 10.0 5.4 5.5 5.3 6.4 2.7 3.9 10.3 4.5 8.5 6.8 10.4 8.5 14.3 12.6 14.4 6.0 10.4 5.0 0.7 0.1 0.1 0.5 0.3 0.1 0.4 0.0 0.2 0.2 0.7 0.3 0.0 0.3 0.4 0.1 1.4 0.7 0.1 4.4 4.0 5.1 4.7 5.0 5.1 5.2 4.7 4.7 3.6 4.5 4.2 13.7 3.2 12.7 11.4 11.8 14.1 5.0 3.8 11.4 4.2 14.3 12.2 1.1 2.8 3.0 5.5 10.4 6.2 15.8 5.9 3.9 4.4 65.4 12.9 7.7 6.1 2.4 5.0 8.6 4.0 11.1 7.0 5.6 16.6 1.3 5.8 4.2 5.6 5.0 5.0 7.6 4.7 2.0 8.5 10.7 67.4 6.5 9.9 1.8 1.9 4.9 6.0 4.1 7.1 8.5 6.0 3.0 3.8 15.9 6.7 3.6 2.0 3.5 6.4 0.0 17.7 8.0 54.1 19.4 11.5 10.7 16.8 11.0 6.1 5.1 8.7 MED9 "FLJ10193, MED25" ENSG00000141026 "Mediator complex subunit 9" Q9NWA0 17 17476994-17493221 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056415 Uncertain Approved Nucleoplasm,Midbody Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 12: NES - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm Midbody "HPA056415: AB_2683120" "unprognostic (1.81e-2)" "unprognostic (4.58e-2)" "unprognostic (2.65e-1)" "unprognostic (3.48e-3)" "unprognostic (1.27e-1)" "unprognostic (2.18e-1)" "unprognostic (1.89e-1)" "unprognostic (3.21e-2)" "unprognostic (4.23e-1)" "unprognostic (7.65e-2)" "prognostic favorable (4.18e-5)" "unprognostic (3.96e-2)" "prognostic favorable (2.83e-9)" "unprognostic (2.26e-3)" "unprognostic (2.29e-1)" "unprognostic (3.09e-1)" "unprognostic (1.39e-1)" 9.3 14.9 21.6 4.9 23.0 10.6 10.3 20.6 28.0 12.4 19.2 11.3 8.2 12.1 11.9 10.2 8.6 4.6 32.7 22.5 21.0 20.4 23.6 7.3 6.8 21.8 22.1 9.4 10.0 18.3 12.8 5.7 20.6 11.8 7.4 9.9 12.9 8.5 27.3 14.2 9.4 5.8 20.9 10.4 12.4 10.9 22.3 11.6 13.8 41.5 6.7 8.8 9.4 21.8 12.0 15.0 12.7 13.7 10.0 9.0 11.0 9.6 11.9 14.5 13.0 22.0 5.9 14.7 10.8 9.9 8.8 15.3 16.3 13.2 13.5 9.6 26.3 9.0 10.0 15.9 10.8 7.2 7.5 14.6 12.3 12.2 12.5 10.8 10.0 21.3 10.7 6.7 9.7 10.1 32.7 14.9 11.7 24.8 15.4 24.8 28.7 9.8 13.0 8.4 8.2 13.0 12.6 9.8 21.7 47.6 11.6 9.3 6.8 10.6 12.3 18.6 15.3 12.4 9.9 8.2 13.3 12.5 11.5 2.6 7.0 11.8 9.3 9.5 12.3 9.9 9.7 9.7 7.7 9.1 10.2 11.4 2.3 10.7 12.4 12.5 10.2 7.8 21.6 23.0 20.6 28.0 22.5 21.0 21.8 22.1 20.6 20.9 22.3 21.8 6.0 3.2 4.4 10.1 5.8 4.6 8.9 5.5 5.2 25.9 8.2 6.7 19.6 10.0 5.0 9.2 14.6 8.6 8.1 9.1 11.7 6.6 8.7 6.0 6.3 6.0 15.7 4.2 14.4 4.5 5.8 5.6 11.7 8.8 0.0 14.5 7.5 5.5 6.1 16.8 12.9 9.6 8.2 4.4 2.8 8.9 5.6 4.0 1.8 1.9 4.7 24.1 10.3 14.1 6.5 3.3 5.7 9.4 7.2 8.4 9.5 6.1 4.0 25.0 0.0 6.0 6.9 10.9 29.9 5.6 4.8 9.6 6.6 13.4 8.1 9.0 MEGF6 EGFL3 ENSG00000162591 "Multiple EGF like domains 6" O75095 1 3487951-3611508 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 22.4;Alveolar cells type 2: 20.6;Basal keratinocytes: 18.4;Basal squamous epithelial cells: 23.3;Melanocytes: 19.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ: 51.1;HeLa: 56.3;hTERT-RPE1: 69.7;U-2197: 55.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052129 Uncertain Approved "Microtubules,Cytokinetic bridge" "Secreted to blood" Yes No 1700000 "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Microtubules "Cytokinetic bridge" "HPA052129: AB_2681739" "unprognostic (1.95e-1)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.16e-2)" "unprognostic (2.38e-1)" "prognostic favorable (6.57e-4)" "unprognostic (1.19e-1)" "unprognostic (4.16e-2)" "unprognostic (1.73e-1)" "unprognostic (1.47e-1)" "unprognostic (2.90e-2)" "unprognostic (2.03e-1)" "unprognostic (3.09e-3)" "unprognostic (1.60e-1)" "unprognostic (1.64e-1)" "unprognostic (9.51e-2)" "unprognostic (3.43e-2)" 25.9 4.3 2.9 3.9 2.7 10.8 20.0 2.6 2.8 14.5 1.4 14.1 2.1 9.6 1.4 13.2 28.9 11.2 14.2 1.9 3.2 5.9 5.0 22.1 5.5 3.5 5.8 18.0 6.5 0.4 4.1 2.8 3.6 26.5 1.1 1.8 19.3 4.7 4.8 44.6 10.0 1.4 2.1 10.7 10.1 3.3 3.7 3.4 11.6 1.9 3.4 11.0 22.8 1.9 11.6 14.1 4.3 6.6 0.4 0.3 1.0 51.1 14.1 5.2 1.6 3.3 10.4 0.0 13.8 24.6 4.4 6.7 0.0 0.5 1.7 0.0 0.4 0.0 56.3 3.3 0.0 0.2 0.9 0.1 0.6 0.4 0.8 69.7 5.6 0.1 0.0 0.0 0.1 6.0 0.0 10.9 2.7 3.3 0.9 2.2 3.0 6.2 1.1 3.8 3.8 3.1 18.8 1.1 6.4 11.4 4.9 1.5 2.2 19.6 1.7 55.6 3.9 0.2 0.0 0.0 0.1 0.0 0.0 1.0 0.0 1.9 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.3 0.0 0.8 0.0 0.0 0.0 0.8 0.1 2.9 2.7 2.6 2.8 1.9 3.2 3.5 5.8 3.6 2.1 3.7 1.9 5.0 22.4 20.6 8.8 2.7 18.4 7.1 3.9 23.3 0.8 3.6 3.0 3.3 5.7 4.4 1.8 0.0 0.2 0.4 0.6 0.0 3.6 0.2 1.4 0.6 7.0 0.0 4.8 6.5 1.4 1.3 9.4 6.6 5.0 1.3 9.8 16.8 0.9 1.0 0.0 7.2 1.4 0.0 0.3 7.5 0.5 11.5 2.8 19.6 5.6 0.7 14.7 1.0 4.5 5.2 4.5 0.1 3.4 0.4 4.0 0.5 1.2 0.3 1.2 0.0 0.5 2.7 0.3 1.1 7.6 11.4 0.4 3.6 0.1 1.1 2.7 MEOX1 MOX1 ENSG00000005102 "Mesenchyme homeobox 1" P50221 17 43640389-43661922 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 36.0;breast: 26.1;heart muscle: 24.9" "Group enriched" "Detected in some" 9 "Adipocytes: 63.5;Endothelial cells: 41.3" "Cancer enhanced" "Detected in many" "ovarian cancer: 6.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 4 "T-reg: 17.5" "Lineage enriched" "Detected in single" 48 "T-cells: 17.5" "Cell line enriched" "Detected in some" 14 "HeLa: 25.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA045214, HPA063788" Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA045214: AB_10959299, HPA063788: " "unprognostic (1.36e-3)" "unprognostic (2.15e-4)" "unprognostic (1.25e-1)" "unprognostic (2.58e-3)" "unprognostic (2.01e-2)" "unprognostic (5.65e-3)" "unprognostic (1.25e-1)" "unprognostic (4.55e-3)" "unprognostic (6.71e-2)" "unprognostic (2.64e-1)" "unprognostic (1.46e-1)" "unprognostic (9.36e-2)" "unprognostic (3.44e-6)" "unprognostic (2.40e-2)" "unprognostic (2.66e-1)" "unprognostic (1.82e-1)" "unprognostic (7.47e-3)" 36.0 0.5 0.0 4.7 0.0 0.0 26.1 0.0 0.1 8.0 0.0 4.7 1.6 5.5 1.1 3.7 9.0 5.7 24.9 0.0 0.0 0.2 0.1 1.4 6.6 0.0 0.0 1.0 1.5 1.2 0.5 0.1 0.0 2.6 2.4 0.0 4.9 1.9 8.3 6.6 5.1 10.6 0.0 10.8 3.0 1.1 0.0 3.0 1.9 17.1 5.3 7.7 7.3 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.1 0.0 0.0 1.8 0.1 0.5 0.0 0.1 0.0 0.0 0.1 0.1 0.0 25.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 4.3 2.7 0.0 0.0 1.7 0.5 0.0 0.3 0.0 0.0 17.5 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 63.5 0.0 0.0 1.0 0.3 4.1 0.0 0.0 1.2 0.0 0.4 0.6 2.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 41.3 0.0 0.0 0.7 0.0 0.3 4.8 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.6 0.0 0.0 0.0 4.0 0.0 0.0 0.3 5.4 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 1.0 0.0 0.1 0.3 1.8 0.1 1.5 0.3 0.0 0.0 MERTK "c-Eyk, mer, RP38, Tyro12" ENSG00000153208 "MER proto-oncogene, tyrosine kinase" Q12866 2 111898607-112029561 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease variant, Proto-oncogene, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 162.6;Kupffer cells: 119.8;Macrophages: 46.5;Microglial cells: 124.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "intermediate monocyte: 8.6;non-classical monocyte: 5.5" "Lineage enriched" "Detected in single" 50 "monocytes: 8.6" "Cell line enhanced" "Detected in many" "CACO-2: 35.1;Hep G2: 39.9;HUVEC TERT2: 38.4;RT4: 23.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036196, HPA075622" Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Midbody,Cytosol" Yes NA 65000000 "Cluster 7: Monocytes - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Endoplasmic reticulum, Midbody, Cytosol" "HPA036196: AB_10670676, HPA075622: AB_2686759" "unprognostic (2.17e-2)" "unprognostic (8.10e-2)" "unprognostic (4.85e-2)" "unprognostic (2.68e-1)" "unprognostic (2.44e-1)" "unprognostic (1.77e-1)" "unprognostic (1.07e-1)" "prognostic favorable (4.74e-4)" "unprognostic (6.84e-2)" "unprognostic (1.25e-1)" "unprognostic (6.22e-2)" "unprognostic (3.72e-1)" "prognostic favorable (4.43e-5)" "unprognostic (5.13e-2)" "unprognostic (2.11e-1)" "unprognostic (5.86e-2)" "unprognostic (2.05e-2)" 20.1 59.8 22.8 13.5 28.0 1.5 15.3 18.0 29.3 12.6 44.7 10.9 12.3 11.5 26.3 8.4 15.5 12.0 7.0 22.0 22.5 11.4 21.0 13.6 13.1 23.5 22.3 12.6 9.9 21.2 15.5 20.1 22.4 14.1 7.9 16.6 6.4 16.3 3.2 6.4 14.3 14.4 18.4 30.6 13.9 17.2 30.1 6.8 10.1 4.6 8.9 13.6 9.4 22.0 1.0 1.7 7.6 17.3 0.4 0.2 12.3 0.0 0.2 1.0 1.7 35.1 2.2 0.1 8.1 0.1 7.9 0.2 10.2 0.0 1.4 1.5 5.5 7.0 0.0 39.9 0.3 0.2 1.5 0.5 0.0 8.9 0.6 4.0 38.4 1.5 2.2 3.5 2.9 1.8 0.0 9.1 4.8 1.1 6.0 2.9 2.1 3.0 19.4 23.4 0.3 7.2 0.2 0.5 3.2 2.7 0.0 0.4 5.8 1.0 3.4 0.1 0.0 3.1 4.8 0.1 0.0 1.4 0.0 0.0 0.6 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 5.5 0.1 0.0 0.2 22.8 28.0 18.0 29.3 22.0 22.5 23.5 22.3 22.4 18.4 30.1 22.0 8.8 3.2 27.7 162.6 1.7 1.7 2.9 0.3 1.8 0.6 2.1 4.3 2.7 2.8 6.4 0.0 2.1 3.3 0.4 1.2 1.9 1.1 2.3 8.0 4.7 10.2 0.0 0.4 5.0 1.0 1.1 3.2 0.5 12.1 0.0 3.8 28.5 9.2 25.5 0.0 7.0 2.0 0.0 119.8 1.8 2.7 5.0 46.5 0.0 124.6 1.5 7.7 0.0 10.6 0.6 1.2 1.9 6.8 10.8 2.9 4.4 1.9 1.5 11.3 6.6 1.5 9.2 0.6 1.5 0.6 1.3 18.9 1.3 3.5 1.9 1.6 METTL14 KIAA1627 ENSG00000145388 "Methyltransferase like 14" Q9HCE5 4 118685392-118715433 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 96.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038002 Supported Supported Nucleoplasm Yes No "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "HPA038002: AB_10672401" "unprognostic (4.48e-1)" "unprognostic (5.13e-2)" "unprognostic (5.98e-3)" "unprognostic (3.44e-2)" "unprognostic (1.33e-1)" "unprognostic (1.83e-1)" "unprognostic (3.75e-2)" "unprognostic (4.40e-1)" "unprognostic (9.97e-2)" "unprognostic (2.40e-2)" "unprognostic (3.64e-2)" "unprognostic (3.33e-3)" "prognostic favorable (1.46e-5)" "unprognostic (1.05e-1)" "unprognostic (1.32e-1)" "unprognostic (1.76e-3)" "unprognostic (7.76e-3)" 8.9 8.8 5.2 8.6 6.0 19.5 11.5 6.8 6.3 8.8 5.5 8.8 8.8 11.7 10.7 8.9 8.8 7.7 8.3 4.8 6.3 10.2 14.9 9.1 11.6 5.5 5.2 12.7 7.8 10.9 8.2 9.0 6.3 9.7 8.2 11.7 7.6 8.0 8.4 10.9 9.2 9.2 5.4 10.8 7.9 15.1 5.7 12.5 10.6 7.7 11.0 8.5 7.9 7.4 19.6 8.9 19.0 17.8 11.7 14.7 13.8 17.1 13.0 12.6 14.4 12.9 22.8 22.0 9.8 12.0 12.6 9.4 16.2 14.1 16.1 17.5 9.8 18.5 11.4 14.4 13.3 30.2 21.2 13.1 15.8 14.6 9.6 16.5 11.5 17.4 20.1 18.2 17.5 13.2 29.7 24.7 16.2 16.7 7.7 16.8 23.7 11.2 13.8 12.7 15.4 17.3 12.0 22.0 17.2 17.2 10.0 28.5 15.8 18.1 16.6 16.3 13.7 15.2 17.0 24.9 12.9 16.5 15.1 37.7 12.8 29.0 17.0 19.6 19.3 24.3 17.8 17.7 15.3 25.3 21.0 19.0 10.3 21.8 23.7 12.1 20.8 13.7 5.2 6.0 6.8 6.3 4.8 6.3 5.5 5.2 6.3 5.4 5.7 7.4 18.6 25.6 25.9 14.7 20.6 10.8 18.3 10.6 16.5 16.8 13.4 12.6 15.7 17.2 20.8 23.9 22.9 18.7 28.3 13.7 11.7 11.9 96.9 14.5 21.7 17.3 12.1 8.4 18.7 15.6 10.2 16.8 9.2 18.0 22.1 18.3 16.4 32.1 12.1 8.4 17.0 15.2 6.1 17.9 7.6 16.7 18.6 13.3 7.2 14.0 14.0 13.4 25.7 14.1 26.9 14.8 13.0 13.9 8.2 17.1 15.4 20.6 15.2 25.4 13.1 15.3 15.5 42.2 28.1 12.4 11.9 15.3 20.6 17.0 12.8 16.0 METTL22 "C16orf68, FLJ12433,MGC2654" ENSG00000067365 "Methyltransferase like 22" Q9BUU2 16 8621683-8649654 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Early spermatids: 119.9;Late spermatids: 357.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 9.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040803, HPA059882, HPA074173" Uncertain Supported "Nucleoplasm,Nucleoli rim" Yes No "Cluster 1: Neutrophils - Mixed function" "Cluster 21: Non-specific - Transcription" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoli rim" Nucleoplasm "HPA040803: AB_10795479, HPA059882: AB_2684150, HPA074173: AB_2686672" "unprognostic (1.74e-1)" "unprognostic (6.50e-2)" "unprognostic (3.02e-1)" "unprognostic (1.41e-1)" "unprognostic (7.83e-2)" "unprognostic (1.52e-1)" "unprognostic (1.39e-1)" "unprognostic (2.58e-2)" "unprognostic (1.80e-2)" "unprognostic (1.10e-1)" "unprognostic (1.94e-3)" "unprognostic (3.82e-2)" "prognostic unfavorable (2.79e-8)" "unprognostic (1.78e-2)" "unprognostic (2.81e-1)" "unprognostic (1.15e-2)" "unprognostic (8.90e-2)" 4.4 5.8 9.0 5.7 10.2 7.7 4.5 16.4 13.2 6.7 9.5 5.9 4.9 5.9 6.1 5.3 5.4 4.4 9.3 8.8 9.1 5.1 6.6 4.7 6.1 12.7 10.7 6.4 6.1 3.1 5.1 5.0 13.3 7.2 4.0 10.4 4.7 5.2 20.2 8.4 4.1 4.7 9.1 4.7 5.1 13.7 12.6 4.0 5.2 5.9 5.0 5.5 5.8 12.9 4.3 8.7 9.7 9.3 3.6 9.1 8.4 7.2 3.8 8.4 9.5 8.5 9.8 6.7 6.3 6.4 3.1 7.9 6.1 11.5 5.5 9.8 8.4 6.9 17.3 24.6 10.8 7.2 5.1 9.2 8.2 9.2 10.1 5.1 6.8 9.2 9.4 6.6 6.5 15.2 7.4 17.0 5.2 1.9 8.5 11.1 7.3 13.9 4.1 4.5 11.9 7.9 6.3 7.3 4.7 5.2 8.0 5.9 5.4 10.0 8.7 8.2 3.3 8.9 5.3 10.4 3.6 9.3 4.7 1.6 2.5 2.0 0.9 1.9 0.9 0.9 0.9 1.0 2.3 0.8 1.1 0.5 9.7 1.6 2.2 1.3 1.2 1.0 9.0 10.2 16.4 13.2 8.8 9.1 12.7 10.7 13.3 9.1 12.6 12.9 5.1 9.6 5.6 8.5 7.6 3.3 6.9 7.5 8.6 13.8 5.8 6.1 18.3 4.3 6.0 0.0 4.2 12.8 2.7 4.9 11.7 9.3 119.9 3.5 6.5 7.2 7.2 18.5 13.4 9.8 9.8 7.4 9.2 3.5 8.2 11.3 5.7 7.4 29.5 1.7 14.3 7.0 2.0 31.8 9.6 357.8 10.8 27.5 1.8 12.2 17.6 4.9 11.3 12.5 13.3 8.4 6.8 13.9 7.7 11.0 8.3 8.9 3.4 11.8 0.0 9.0 8.5 39.6 15.7 7.5 2.7 13.3 6.6 7.8 6.5 8.1 MGAT5B "FLJ25132, GnT-IX, GnT-VB" ENSG00000167889 "Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B" Q3V5L5 17 76868404-76950393 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 12.0" "Cell type enhanced" "Detected in some" "Astrocytes: 16.0;Early spermatids: 7.3;Excitatory neurons: 26.2;Inhibitory neurons: 21.9;Late spermatids: 8.1" "Group enriched" "Detected in many" 5 "glioma: 2.6;melanoma: 7.1;testis cancer: 2.4" "Region enhanced" "Detected in many" "cerebral cortex: 12.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 32.1;SCLC-21H: 15.9;U-138 MG: 19.2;U-2 OS: 20.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011082 Approved "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" Yes No "Cluster 10: Brain - Neuronal signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Mitotic spindle" "Cytokinetic bridge" "HPA011082: AB_2668423" "unprognostic (6.37e-2)" "unprognostic (9.16e-3)" "unprognostic (8.51e-2)" "unprognostic (1.43e-3)" "unprognostic (5.68e-3)" "unprognostic (1.33e-1)" "unprognostic (2.28e-3)" "unprognostic (1.52e-3)" "unprognostic (5.30e-2)" "unprognostic (3.89e-2)" "unprognostic (1.68e-1)" "unprognostic (5.67e-2)" "unprognostic (1.46e-7)" "unprognostic (1.66e-1)" "unprognostic (8.09e-3)" "unprognostic (1.04e-1)" "unprognostic (3.01e-1)" 0.2 0.2 2.4 0.2 2.1 0.1 0.1 0.0 12.0 0.2 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.1 0.0 5.2 0.0 0.2 0.0 0.3 0.1 0.3 0.0 0.2 0.0 0.2 0.9 0.2 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.1 1.2 0.0 0.2 0.2 0.1 0.0 0.1 0.1 0.0 3.7 32.1 6.4 3.4 0.0 0.0 3.7 0.4 1.3 11.7 6.9 0.1 0.7 0.0 2.5 1.5 13.7 0.2 1.6 0.2 3.0 0.1 0.5 0.0 1.7 0.1 0.0 0.0 0.2 0.1 0.2 0.0 1.8 5.2 2.0 0.7 0.2 0.0 0.0 1.5 0.1 0.0 1.8 0.8 3.5 4.8 5.6 7.1 8.9 0.1 15.9 6.1 5.5 2.4 5.0 0.4 0.2 0.2 5.8 19.2 20.9 0.3 6.3 0.0 0.0 0.7 0.6 0.0 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 2.1 0.0 12.0 5.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 16.0 0.1 0.1 0.1 0.0 0.0 5.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.1 0.1 0.8 0.0 0.0 26.2 0.0 3.2 0.2 0.0 0.2 0.0 0.6 0.7 0.0 0.1 0.0 21.9 0.0 0.0 0.0 0.0 8.1 0.6 0.0 0.0 2.8 0.0 0.2 0.0 5.0 1.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.0 0.1 1.1 2.4 0.0 0.0 0.1 0.1 0.2 0.0 0.0 MICAL3 KIAA0819 ENSG00000243156 "Microtubule associated monooxygenase, calponin and LIM domain containing 3" Q7RTP6 22 17787649-18024561 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Exocytosis" "Actin-binding, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 104.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 176.5;Inhibitory neurons: 164.6;Oligodendrocytes: 216.0" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 104.9" "Immune cell enriched" "Detected in some" 4 "basophil: 11.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 11.1" "Cell line enhanced" "Detected in all" "WM-115: 131.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000639, HPA003421, HPA034882" Approved Supported "Nucleoplasm,Plasma membrane,Midbody ring,Cytosol" Yes No "Cluster 38: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Midbody ring" "Plasma membrane, Cytosol" "HPA000639: AB_10301319, HPA003421: AB_10601134, HPA034882: AB_2674371" "unprognostic (1.65e-1)" "unprognostic (1.02e-1)" "unprognostic (3.67e-2)" "unprognostic (2.00e-2)" "unprognostic (7.68e-2)" "unprognostic (2.06e-1)" "unprognostic (4.71e-2)" "unprognostic (3.07e-3)" "unprognostic (3.41e-1)" "unprognostic (1.01e-1)" "unprognostic (4.58e-1)" "unprognostic (3.82e-1)" "unprognostic (8.86e-3)" "unprognostic (1.36e-2)" "unprognostic (1.23e-1)" "unprognostic (2.03e-2)" "unprognostic (6.64e-2)" 15.9 12.0 18.3 14.9 20.3 17.3 11.2 104.9 34.5 16.5 3.6 28.1 11.0 31.0 17.0 19.6 38.6 13.4 35.6 14.3 13.7 10.9 18.8 8.3 23.0 13.2 6.4 26.5 14.0 38.5 7.2 16.7 15.6 16.4 20.6 14.1 10.9 19.8 48.2 18.9 14.5 37.3 1.9 17.8 10.7 24.4 12.7 6.0 14.7 20.8 20.3 15.9 12.0 45.9 34.0 39.6 20.2 33.7 15.6 19.2 25.6 32.6 33.1 43.6 34.5 36.1 4.8 35.1 15.5 39.3 51.2 38.7 30.1 31.9 43.0 35.6 25.2 35.9 44.6 11.9 9.6 17.1 20.2 14.4 25.9 46.9 43.7 25.2 24.9 9.7 47.6 22.8 16.9 26.6 16.9 10.7 13.0 27.3 26.4 23.2 30.3 1.9 32.1 24.8 53.5 21.1 40.6 26.0 65.2 31.5 10.8 7.0 43.9 46.0 28.4 29.7 63.6 16.4 30.2 50.8 40.0 7.7 131.6 11.1 0.0 0.1 0.3 0.0 0.6 2.5 0.3 0.3 0.0 2.6 0.2 0.1 0.1 0.9 0.0 0.2 0.7 0.2 18.3 20.3 104.9 34.5 14.3 13.7 13.2 6.4 15.6 1.9 12.7 45.9 19.6 3.2 10.2 57.1 32.1 11.2 15.2 17.9 13.1 20.9 13.7 15.5 16.5 12.8 13.2 12.9 52.1 14.1 6.2 43.5 0.0 23.9 10.5 36.4 10.2 16.4 10.2 19.3 176.5 9.8 40.3 10.5 13.3 38.8 19.0 9.7 8.9 37.3 3.1 1.7 164.6 20.8 8.2 3.2 9.6 13.9 4.1 4.2 8.8 23.4 6.0 38.2 5.2 71.9 216.0 24.6 23.6 6.4 12.5 14.4 19.8 5.5 27.8 12.2 0.0 11.0 12.1 19.8 13.8 11.2 11.8 11.2 9.1 24.2 21.5 10.1 MIDN ENSG00000167470 Midnolin Q504T8 19 1248553-1259140 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 455.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 11.8" "Lineage enriched" "Detected in many" 9 "granulocytes: 11.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042018, HPA049432" Uncertain Approved Nucleoplasm Yes No "Cluster 1: Neutrophils - Mixed function" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA042018: AB_2677800, HPA049432: AB_2680765" "unprognostic (1.82e-2)" "unprognostic (6.21e-2)" "unprognostic (2.27e-2)" "unprognostic (2.18e-2)" "unprognostic (2.40e-1)" "unprognostic (2.24e-3)" "unprognostic (1.06e-2)" "unprognostic (2.04e-2)" "unprognostic (2.29e-2)" "unprognostic (1.33e-1)" "unprognostic (3.03e-1)" "unprognostic (1.71e-1)" "unprognostic (1.49e-2)" "unprognostic (1.21e-1)" "unprognostic (1.33e-1)" "unprognostic (3.56e-1)" "unprognostic (1.19e-2)" 71.4 61.9 25.6 25.2 25.0 82.6 42.7 24.9 32.3 48.0 16.1 53.9 22.3 34.2 6.3 99.2 64.6 31.4 72.9 21.1 32.1 46.9 50.5 67.0 19.1 44.8 30.1 61.4 37.4 8.2 81.9 15.5 29.8 39.2 12.0 12.4 46.6 11.5 141.6 79.1 52.6 12.4 29.8 50.3 56.1 19.6 32.4 19.0 35.0 17.4 15.1 42.2 55.7 23.1 14.7 31.8 53.5 25.0 11.2 19.0 39.2 25.0 14.9 12.6 8.9 41.8 16.1 23.3 26.6 18.9 6.8 29.6 16.3 26.5 4.9 32.9 30.0 32.8 21.8 33.3 22.7 33.3 46.9 29.4 24.4 15.1 14.3 19.5 20.8 27.3 42.7 24.0 13.5 58.9 44.6 13.6 117.6 28.6 21.1 68.8 15.2 10.7 23.8 17.2 42.7 55.9 52.9 50.1 33.7 27.7 20.2 37.7 26.2 22.9 25.4 106.2 27.3 22.4 13.2 32.2 43.9 14.6 79.5 1.6 1.0 1.1 1.0 1.0 0.7 0.2 0.3 0.7 0.4 0.3 0.2 0.5 11.8 1.3 1.1 0.4 0.1 0.7 25.6 25.0 24.9 32.3 21.1 32.1 44.8 30.1 29.8 29.8 32.4 23.1 330.7 38.5 60.5 17.3 101.1 98.9 128.3 114.4 175.8 53.9 290.6 224.2 84.3 117.2 86.2 134.3 31.3 15.8 184.8 455.8 19.6 125.5 34.7 220.6 84.5 186.1 164.5 19.4 8.0 155.5 47.3 84.0 132.0 294.7 61.5 60.6 197.4 80.9 77.9 21.9 5.6 219.5 59.0 100.0 134.9 33.3 49.7 150.9 42.7 24.4 49.7 77.8 96.8 32.2 10.3 259.0 306.8 33.1 69.9 190.9 242.1 35.8 109.6 35.7 39.5 219.8 142.4 3.3 12.0 227.3 148.0 81.3 122.9 33.2 167.8 190.7 MKI67 "MIB-1, PPP1R105" ENSG00000148773 "Marker of proliferation Ki-67" P46013 10 128096659-128126423 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 46.3;lymphoid tissue: 52.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 232.9;Extravillous trophoblasts: 86.1;Granulosa cells: 87.0;Plasma cells: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB000058, HPA000451, HPA001164, CAB068198" Enhanced Enhanced "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli rim" "Mitotic chromosome" "CAB000058: AB_2142367, CAB068198: AB_2665702, HPA000451: AB_1079186, HPA001164: AB_1079187" "unprognostic (2.54e-1)" "unprognostic (1.29e-1)" "unprognostic (3.37e-1)" "unprognostic (9.92e-3)" "unprognostic (3.17e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (3.61e-6)" "unprognostic (7.16e-3)" "unprognostic (1.45e-2)" "unprognostic (3.73e-1)" "prognostic unfavorable (9.47e-5)" "unprognostic (2.45e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.42e-2)" "unprognostic (2.10e-1)" "unprognostic (2.50e-1)" "unprognostic (4.61e-1)" 0.9 0.7 0.0 8.5 0.1 46.3 1.7 0.0 0.1 1.2 0.2 8.1 6.2 1.0 0.0 10.0 0.3 0.9 0.3 0.1 0.1 0.4 0.8 1.4 14.9 0.1 1.0 0.2 0.2 0.1 0.1 4.1 0.6 0.4 9.2 0.0 1.4 0.1 0.0 6.6 5.8 2.6 0.0 4.8 4.2 2.3 0.9 52.7 0.4 0.1 16.4 1.8 2.8 0.3 204.6 101.5 103.2 73.6 4.3 8.7 32.1 75.7 55.3 70.3 62.3 83.9 82.3 152.6 21.3 51.9 46.4 120.7 109.3 56.8 104.7 161.8 53.1 131.0 79.4 52.7 0.1 186.0 68.0 2.0 2.5 72.2 73.2 17.2 69.8 69.5 61.2 142.1 70.5 80.9 111.7 56.6 41.3 52.7 45.7 82.2 135.1 20.3 25.6 56.2 35.9 38.9 107.1 38.0 17.3 33.9 31.4 39.3 65.0 37.0 73.6 53.0 206.8 64.2 54.9 177.2 30.7 83.3 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 1.0 0.6 0.0 0.9 0.3 0.6 0.0 5.4 0.0 16.0 6.4 1.6 5.3 0.6 0.0 3.9 3.2 1.6 1.5 5.3 0.0 0.0 30.6 7.4 25.0 0.0 0.8 4.2 2.3 10.2 6.7 6.7 232.9 0.0 0.0 86.1 13.5 34.7 13.2 1.3 87.0 5.7 1.7 42.1 0.0 0.0 22.4 2.0 12.9 13.7 0.9 0.3 16.6 3.6 0.0 0.2 0.0 8.2 0.0 0.0 0.1 3.0 0.4 107.4 4.6 2.6 0.1 1.6 0.0 0.0 0.5 13.6 8.1 24.1 50.4 3.0 7.8 23.0 2.7 47.1 4.8 MMP24 MT5-MMP ENSG00000125966 "Matrix metallopeptidase 24" Q9Y5R2 20 35226690-35276998 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 40.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 16.0;Excitatory neurons: 24.6;Horizontal cells: 15.2;Inhibitory neurons: 38.4;Oligodendrocyte precursor cells: 12.5;Oligodendrocytes: 12.0;Proximal tubular cells: 11.4" "Cancer enhanced" "Detected in many" "renal cancer: 11.4;testis cancer: 10.8" "Region enriched" "Detected in all" 5 "cerebellum: 40.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 36.3;CACO-2: 56.0;EFO-21: 15.8;RPTEC TERT1: 24.6;U-2 OS: 17.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 51.5" "HPA049280, HPA078816" Approved Approved "Nucleoli,Plasma membrane" "Secreted to extracellular matrix" Yes No "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 39: CACO-2 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoli, Plasma membrane" "HPA049280: , HPA078816: " "unprognostic (1.52e-3)" "unprognostic (1.36e-1)" "unprognostic (1.18e-1)" "unprognostic (4.51e-4)" "unprognostic (2.47e-2)" "unprognostic (7.61e-3)" "unprognostic (1.22e-1)" "unprognostic (4.59e-2)" "unprognostic (2.32e-2)" "unprognostic (8.82e-2)" "unprognostic (9.20e-3)" "unprognostic (7.12e-2)" "prognostic favorable (8.17e-11)" "unprognostic (3.32e-2)" "unprognostic (5.63e-2)" "unprognostic (1.69e-2)" "unprognostic (9.90e-4)" 3.4 1.0 6.1 0.5 5.8 0.7 0.5 40.0 8.1 0.7 3.5 0.7 2.1 1.3 0.1 0.3 2.2 0.6 0.6 6.0 5.6 7.8 0.5 4.7 0.4 4.4 5.6 0.4 5.8 0.3 3.8 0.2 5.4 1.7 0.2 2.5 0.5 4.2 0.3 1.2 1.4 2.0 2.7 0.4 0.6 0.4 7.2 0.0 0.7 0.1 0.0 0.4 0.3 4.8 0.6 36.3 0.1 0.2 0.2 0.0 1.0 1.9 2.3 3.8 2.0 56.0 9.7 0.0 15.8 2.5 1.2 0.6 8.5 0.0 1.6 0.2 0.3 1.9 1.2 0.6 0.0 0.1 0.4 0.2 0.2 0.1 0.1 1.0 0.1 0.1 0.1 0.5 0.4 0.5 0.1 0.2 13.6 0.1 2.4 0.1 0.2 0.0 24.6 0.1 14.1 9.7 2.5 0.7 0.3 2.9 0.5 0.3 0.6 7.4 17.7 1.8 0.7 0.3 0.2 0.1 1.6 0.2 1.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 6.1 5.8 40.0 8.1 6.0 5.6 4.4 5.6 5.4 2.7 7.2 4.8 0.3 16.0 1.5 5.2 0.0 0.1 0.2 0.0 0.0 3.9 0.2 0.8 0.5 8.6 1.3 1.8 0.0 0.1 0.1 0.7 5.9 8.5 0.6 0.8 0.3 1.4 0.0 0.0 24.6 0.9 0.1 0.6 0.0 0.5 0.0 0.1 0.4 0.4 0.0 15.2 38.4 0.1 0.0 0.6 0.0 0.0 0.3 0.1 1.8 10.3 0.0 0.2 0.0 12.5 12.0 1.9 0.1 0.0 0.0 0.4 2.3 11.4 0.0 0.4 0.0 0.2 0.2 0.1 0.3 0.0 0.3 0.0 0.2 0.0 0.1 0.1 MPHOSPH10 "CT90, MPP10, MPP10P, PPP1R106" ENSG00000124383 "M-phase phosphoprotein 10" O00566 2 71130632-71150101 "Predicted intracellular proteins, Predicted membrane proteins" "Ribosome biogenesis, rRNA processing" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035059, HPA035060, HPA049907" Enhanced Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA035059: AB_2674436, HPA035060: AB_10601875, HPA049907: AB_2680947" "unprognostic (3.20e-3)" "unprognostic (1.59e-1)" "unprognostic (8.51e-2)" "unprognostic (5.77e-2)" "unprognostic (1.03e-1)" "unprognostic (1.62e-1)" "unprognostic (3.58e-2)" "unprognostic (1.01e-1)" "unprognostic (6.41e-3)" "unprognostic (6.13e-2)" "unprognostic (3.50e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (3.89e-7)" "unprognostic (1.24e-1)" "unprognostic (2.91e-1)" "unprognostic (2.47e-1)" "unprognostic (2.23e-2)" 22.6 18.4 15.2 20.4 16.4 26.5 25.0 17.7 21.4 19.9 15.4 17.6 17.7 22.1 27.5 28.6 16.6 18.4 23.2 15.3 17.7 17.8 30.8 16.9 25.2 17.1 17.0 25.9 19.7 22.9 15.8 20.3 17.0 24.6 19.1 15.1 21.0 16.7 33.1 26.7 15.5 16.8 15.6 19.6 17.8 15.4 16.3 22.5 21.7 24.0 27.5 23.8 18.1 17.6 45.8 33.7 42.7 51.3 39.1 36.7 58.3 49.8 39.6 40.6 29.7 60.7 32.9 64.3 30.5 35.3 31.0 41.1 54.8 35.3 54.1 44.7 43.2 77.3 26.3 139.1 34.1 101.0 58.2 32.0 44.4 33.4 44.4 27.4 34.8 39.1 113.5 49.1 41.0 49.1 81.6 101.5 71.0 63.5 38.1 66.6 66.7 75.4 33.1 49.0 51.8 40.0 33.6 75.0 49.9 36.1 38.2 44.5 36.0 47.2 51.1 45.3 64.0 41.0 50.6 104.1 40.5 82.8 49.1 17.6 12.4 9.8 15.2 17.8 20.2 18.0 19.6 18.8 15.3 15.0 21.4 19.2 1.9 17.1 26.1 16.3 18.3 11.3 15.2 16.4 17.7 21.4 15.3 17.7 17.1 17.0 17.0 15.6 16.3 17.6 38.6 35.3 55.5 8.1 36.8 33.4 42.7 37.8 30.7 37.2 26.0 36.8 44.5 30.0 53.0 18.4 4.2 50.5 47.7 17.9 25.4 47.8 6.0 40.4 52.4 40.4 18.0 26.9 9.8 41.8 48.1 43.2 19.9 65.4 48.1 31.2 21.8 33.2 27.2 18.5 11.4 21.6 26.4 17.7 20.8 6.3 48.7 19.0 12.4 15.0 39.2 25.5 47.4 12.1 15.9 33.1 15.0 43.6 25.6 40.6 14.2 22.7 29.2 53.2 39.5 62.2 49.1 70.2 84.5 35.6 33.5 32.4 39.9 42.8 28.2 31.9 MRPL52 ENSG00000172590 "Mitochondrial ribosomal protein L52" Q86TS9 14 22829879-22835037 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 549.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012319 Approved Supported Nucleoplasm,Mitochondria Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 7: Non-specific - Mitochondria" Mitochondria Nucleoplasm "HPA012319: AB_1854118" "unprognostic (8.98e-2)" "unprognostic (9.07e-2)" "unprognostic (1.36e-1)" "unprognostic (3.18e-1)" "unprognostic (1.36e-1)" "unprognostic (4.74e-2)" "unprognostic (4.01e-3)" "unprognostic (1.29e-1)" "unprognostic (6.52e-2)" "unprognostic (8.05e-3)" "unprognostic (8.07e-2)" "unprognostic (2.87e-1)" "unprognostic (7.46e-2)" "unprognostic (2.19e-1)" "unprognostic (1.40e-1)" "unprognostic (3.16e-1)" "unprognostic (1.41e-1)" 76.5 105.6 106.9 53.7 109.6 51.9 72.4 113.6 130.8 66.5 109.4 88.3 70.0 72.8 30.8 141.6 61.0 20.6 193.7 107.7 110.4 130.8 154.2 73.5 41.7 113.4 109.8 59.9 108.7 70.6 70.1 32.9 113.6 83.5 33.9 15.2 79.6 35.6 155.2 96.6 77.7 25.6 111.5 96.3 113.4 67.7 112.0 62.0 83.2 55.4 41.3 85.0 78.2 112.9 237.5 181.4 97.4 121.4 59.3 69.1 236.8 161.2 115.0 140.8 133.4 224.1 321.9 178.8 172.5 111.3 143.4 210.8 79.8 223.4 105.6 190.8 132.6 133.6 65.6 518.5 180.3 211.9 183.6 104.8 150.4 182.7 154.5 111.2 226.6 222.7 139.4 172.8 104.6 329.2 172.5 320.0 180.1 292.5 397.5 210.2 121.5 210.4 149.9 138.7 96.8 125.1 124.5 120.6 178.3 68.9 116.0 198.9 176.5 146.4 172.0 185.1 249.2 169.4 219.1 228.0 133.3 143.3 239.6 101.5 111.2 60.2 74.5 128.9 69.5 140.9 82.2 68.2 159.1 111.6 75.9 74.2 19.1 74.5 96.4 131.3 100.7 98.5 106.9 109.6 113.6 130.8 107.7 110.4 113.4 109.8 113.6 111.5 112.0 112.9 105.5 73.7 85.4 5.2 132.5 121.2 88.0 169.2 98.4 23.2 131.2 145.2 103.4 167.3 118.0 136.1 18.8 177.3 82.5 220.9 277.8 245.2 72.4 106.5 89.8 104.4 138.0 112.5 5.7 314.5 287.7 65.8 165.1 116.3 123.0 70.5 106.4 291.0 236.2 20.2 6.2 268.0 107.8 140.2 125.1 58.3 55.9 120.1 124.5 6.5 221.5 80.4 107.1 5.5 9.1 396.9 215.6 49.2 156.4 111.8 313.7 549.8 99.9 33.7 65.7 70.7 147.7 135.4 105.3 190.8 149.2 126.0 85.0 80.3 233.8 98.8 MRRF RRF ENSG00000148187 "Mitochondrial ribosome recycling factor" Q96E11 9 122264603-122331337 "Predicted intracellular proteins" "Protein biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 210.0;Late spermatids: 191.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047177, HPA049987" Supported Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" "Microtubules, Cytokinetic bridge" "HPA047177: AB_2679970, HPA049987: AB_2680984" "unprognostic (8.38e-2)" "unprognostic (2.17e-1)" "unprognostic (6.40e-2)" "unprognostic (6.06e-3)" "unprognostic (3.64e-2)" "unprognostic (1.11e-1)" "unprognostic (4.48e-2)" "unprognostic (3.71e-2)" "unprognostic (1.89e-2)" "unprognostic (4.44e-2)" "unprognostic (2.98e-1)" "unprognostic (9.01e-2)" "prognostic favorable (2.14e-8)" "unprognostic (3.89e-2)" "unprognostic (4.05e-1)" "unprognostic (8.02e-2)" "unprognostic (8.88e-3)" 18.9 19.3 10.4 12.1 10.7 14.2 19.3 11.7 13.3 13.9 15.3 25.1 23.7 10.1 13.1 25.5 11.4 8.8 28.2 10.6 11.3 23.4 24.3 13.3 14.0 11.4 10.9 11.3 18.3 23.2 12.5 9.0 11.3 14.7 28.6 14.5 15.3 10.6 40.6 22.1 18.5 10.1 10.6 15.6 14.4 18.1 11.3 13.8 16.3 32.1 20.4 16.9 16.4 11.5 34.7 45.8 25.6 43.0 35.7 32.5 48.7 33.7 43.0 44.5 26.0 55.0 40.6 75.0 16.7 27.0 35.5 99.3 74.1 78.8 36.3 25.2 30.3 25.6 53.4 30.5 23.6 72.3 32.7 30.5 52.7 40.0 70.8 22.4 50.4 29.6 44.2 27.8 45.1 55.1 36.2 23.6 30.0 86.0 45.7 26.8 48.8 79.7 76.6 34.8 30.3 19.9 36.2 58.3 27.9 24.3 62.8 18.2 27.1 19.5 29.6 51.0 42.0 19.1 50.1 33.0 36.8 42.4 22.8 4.7 17.5 6.0 13.3 29.0 14.2 15.6 13.3 12.5 29.8 12.7 13.8 16.5 2.0 22.9 31.3 12.9 16.3 11.1 10.4 10.7 11.7 13.3 10.6 11.3 11.4 10.9 11.3 10.6 11.3 11.5 22.7 3.2 9.1 21.9 18.8 15.4 22.1 30.3 26.2 13.2 20.1 17.3 21.8 18.6 17.8 14.7 12.5 29.0 10.8 21.4 35.2 36.0 210.0 16.2 15.7 22.5 7.8 29.3 28.6 29.5 49.2 11.1 23.9 12.1 24.7 14.5 14.3 19.2 30.4 5.0 39.1 22.0 18.3 17.0 16.5 191.7 9.6 16.0 14.2 20.6 18.3 6.3 11.3 22.1 31.0 24.0 20.6 7.5 19.4 18.1 41.2 37.3 16.2 23.5 19.7 15.1 11.7 30.2 16.6 32.5 22.4 37.1 12.3 31.1 33.9 22.7 MRTO4 "C1orf33, dJ657E11.4, MRT4" ENSG00000053372 "MRT4 homolog, ribosome maturation factor" Q9UKD2 1 19251805-19260128 "Predicted intracellular proteins, Ribosomal proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026446 Approved Approved "Nucleoplasm,Nuclear membrane,Nucleoli" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nuclear membrane" Nucleoli "HPA026446: AB_10601441" "unprognostic (3.99e-1)" "unprognostic (1.75e-1)" "unprognostic (2.18e-2)" "unprognostic (2.94e-1)" "unprognostic (4.12e-1)" "unprognostic (4.22e-2)" "prognostic unfavorable (1.56e-8)" "unprognostic (7.46e-2)" "unprognostic (5.58e-2)" "unprognostic (2.61e-2)" "unprognostic (2.69e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (4.11e-8)" "unprognostic (5.87e-2)" "unprognostic (1.16e-1)" "unprognostic (2.50e-1)" "unprognostic (3.23e-2)" 18.9 18.5 17.0 16.8 17.1 13.4 20.2 14.8 17.9 13.0 13.7 13.5 16.8 15.8 12.9 23.7 17.6 8.9 14.4 17.4 16.1 17.9 20.3 11.1 20.0 15.8 16.0 17.0 23.4 12.5 8.9 12.1 16.1 12.9 16.5 7.2 12.3 10.5 22.7 17.4 19.5 16.7 15.4 13.8 15.5 14.0 16.1 14.8 11.1 11.4 22.8 21.4 14.1 16.4 90.9 65.9 51.1 67.0 24.2 38.6 44.7 69.0 38.9 116.7 76.1 92.9 92.0 133.6 56.7 60.5 50.4 70.1 142.7 104.6 114.0 47.4 109.6 98.4 55.4 80.8 30.3 133.4 38.7 34.0 69.8 131.6 69.6 31.7 66.1 59.0 151.1 42.3 68.9 68.0 106.3 96.5 65.0 95.6 95.4 99.3 62.7 100.5 64.8 31.3 82.9 59.2 54.0 73.0 75.4 37.6 50.8 76.5 44.2 61.9 77.5 97.6 118.0 33.8 64.3 178.2 61.2 172.4 102.5 1.4 11.6 1.3 11.4 12.7 22.9 23.1 13.7 15.9 17.6 19.7 18.4 16.7 1.4 16.6 10.2 19.7 10.6 11.4 17.0 17.1 14.8 17.9 17.4 16.1 15.8 16.0 16.1 15.4 16.1 16.4 30.0 6.4 14.5 6.2 31.2 37.3 59.1 45.8 42.7 20.4 23.6 37.7 10.3 38.6 26.4 7.3 10.4 50.4 14.9 15.7 41.1 61.8 23.3 19.1 46.8 32.1 21.6 31.3 8.4 55.0 69.9 29.5 19.4 21.1 26.0 36.8 15.4 16.3 47.1 15.2 7.3 25.4 36.7 13.3 18.2 36.5 23.0 21.0 19.6 1.9 32.0 25.7 16.5 4.5 4.3 57.5 17.0 20.3 29.0 57.4 6.0 37.9 15.8 16.4 19.7 44.8 35.9 55.6 49.7 48.2 33.5 26.0 18.6 58.1 34.8 36.7 MTBP ENSG00000172167 "MDM2 binding protein" Q96DY7 8 120445400-120542133 "Predicted intracellular proteins" "Cell cycle, Growth arrest, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 12.8;Excitatory neurons: 14.7;Oligodendrocytes: 16.1;Spermatocytes: 16.2;Spermatogonia: 10.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "SK-BR-3: 44.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA025694, HPA050594" Uncertain Approved "Nucleoplasm,Nuclear bodies" Yes No "Cluster 22: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA025694: AB_1854169, HPA050594: AB_2681185" "unprognostic (1.92e-2)" "unprognostic (1.07e-1)" "unprognostic (4.47e-1)" "unprognostic (3.53e-4)" "unprognostic (1.20e-1)" "unprognostic (5.40e-3)" "unprognostic (2.77e-6)" "unprognostic (3.99e-3)" "unprognostic (1.50e-2)" "unprognostic (7.86e-3)" "unprognostic (3.38e-3)" "unprognostic (3.29e-1)" "unprognostic (5.20e-10)" "unprognostic (3.41e-3)" "unprognostic (2.51e-1)" "unprognostic (3.02e-2)" "unprognostic (5.86e-2)" 1.3 1.1 1.0 2.5 1.2 4.0 2.6 3.6 1.7 1.6 0.7 1.7 1.5 2.1 2.4 1.4 1.7 1.2 0.6 1.0 0.9 1.0 0.8 1.3 4.3 1.0 1.0 2.4 0.9 1.0 0.8 2.1 1.2 1.5 2.6 4.3 1.1 1.0 0.7 3.0 1.3 2.0 0.9 1.8 1.1 5.0 1.1 4.6 0.8 0.8 4.0 1.0 1.3 1.4 15.3 4.5 14.6 6.0 2.1 3.5 7.1 11.4 6.5 16.4 21.0 4.9 8.3 13.8 11.2 3.8 4.9 13.0 13.9 6.8 20.3 11.5 10.6 11.6 6.7 5.6 1.1 12.4 8.6 1.3 2.9 12.7 8.1 2.5 7.3 12.6 7.6 10.2 9.7 6.9 19.8 7.6 6.5 12.0 9.0 11.3 15.0 9.8 3.9 5.3 7.4 8.6 7.7 44.8 7.0 7.9 8.5 8.9 4.5 7.0 12.7 9.0 18.6 3.9 8.9 8.0 6.6 15.1 8.3 0.0 0.1 0.1 0.3 0.6 0.5 0.7 0.5 0.7 0.2 0.5 0.8 0.7 0.0 0.5 0.3 0.0 0.7 0.3 1.0 1.2 3.6 1.7 1.0 0.9 1.0 1.0 1.2 0.9 1.1 1.4 1.6 0.0 1.5 7.5 2.9 0.8 1.7 1.5 1.8 0.0 1.4 1.3 1.1 0.0 1.1 1.8 0.0 2.3 2.5 0.5 0.0 0.9 0.8 1.3 2.6 1.1 0.0 12.8 14.7 1.8 3.0 2.5 2.6 1.5 2.5 5.0 1.8 0.9 1.6 0.0 9.1 0.9 0.0 0.3 1.8 0.4 1.5 1.7 1.8 3.7 1.0 0.0 2.1 9.0 16.1 0.6 0.1 1.2 2.3 1.2 0.3 0.3 2.4 0.0 0.0 5.6 2.6 16.2 10.2 1.4 0.6 0.7 3.3 1.5 0.8 0.8 MTERF4 "MGC61716, MTERFD2" ENSG00000122085 "Mitochondrial transcription termination factor 4" Q7Z6M4 2 241072169-241102332 "Predicted intracellular proteins" "rRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027097 Uncertain Supported Mitochondria,Cytosol Yes No "Cluster 32: T-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" "Mitochondria, Cytosol" "HPA027097: AB_10603879" "unprognostic (4.58e-2)" "unprognostic (3.66e-1)" "unprognostic (2.82e-1)" "unprognostic (5.95e-2)" "unprognostic (1.50e-1)" "unprognostic (6.70e-2)" "unprognostic (1.17e-3)" "unprognostic (2.99e-2)" "unprognostic (2.68e-2)" "unprognostic (1.20e-2)" "prognostic favorable (3.48e-4)" "unprognostic (2.28e-2)" "unprognostic (1.65e-2)" "unprognostic (1.92e-1)" "unprognostic (4.41e-2)" "unprognostic (1.75e-1)" "unprognostic (1.13e-1)" 15.4 15.7 8.7 22.7 10.6 23.8 21.8 17.5 14.5 21.8 6.7 18.2 16.1 25.3 16.1 19.4 19.0 14.2 17.3 9.1 10.3 15.7 20.4 17.0 38.8 9.1 8.3 27.9 17.5 16.2 15.3 14.2 9.6 33.8 19.9 29.4 19.8 18.1 54.4 17.6 22.0 20.1 6.4 22.0 18.3 10.2 9.1 25.1 34.7 41.8 30.8 14.8 16.0 12.7 17.2 14.9 29.7 16.4 38.2 17.5 22.1 27.4 31.5 25.8 36.0 10.5 23.2 24.7 10.0 31.0 30.8 17.6 41.0 38.5 33.8 35.4 28.9 32.2 30.5 46.5 25.5 40.2 23.3 29.0 37.8 30.2 35.6 32.8 30.2 32.4 29.4 10.5 31.9 24.0 28.2 26.4 33.7 35.5 25.8 27.7 33.1 14.1 24.8 31.5 26.2 22.9 20.3 26.8 20.7 19.5 19.6 19.4 39.3 23.4 23.0 27.3 25.7 28.0 7.9 61.2 19.8 24.1 21.4 8.3 10.8 24.9 18.6 10.5 22.7 32.3 29.1 26.8 12.3 31.8 46.0 36.7 3.4 18.1 8.7 9.1 32.5 22.1 8.7 10.6 17.5 14.5 9.1 10.3 9.1 8.3 9.6 6.4 9.1 12.7 20.7 12.8 27.7 40.8 45.6 0.0 20.3 0.0 15.9 0.0 19.8 23.9 19.8 27.1 13.0 20.2 0.0 30.2 34.1 12.1 41.1 24.1 49.2 11.7 19.1 22.4 10.9 22.9 31.2 24.6 28.2 18.6 14.3 12.0 11.4 37.9 20.0 30.6 24.8 0.0 28.8 20.7 0.0 24.5 0.0 61.0 23.3 17.0 0.0 25.3 31.6 0.0 42.2 33.2 39.8 23.7 20.7 26.4 44.8 22.0 43.4 51.4 17.5 0.0 39.5 22.7 18.4 59.0 34.3 23.4 0.0 23.7 37.0 42.9 17.2 17.1 MTUS2 "CAZIP, ICIS, KIAA0774, TIP150" ENSG00000132938 "Microtubule associated scaffold protein 2" Q5JR59 13 28820339-29505947 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "heart muscle: 50.2" "Group enriched" "Detected in some" 4 "Excitatory neurons: 548.4;Inhibitory neurons: 671.8" "Cancer enhanced" "Detected in some" "urothelial cancer: 0.9" "Region enhanced" "Detected in many" "cerebral cortex: 9.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HaCaT: 13.2;HeLa: 5.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031473, HPA031474, HPA031475" Enhanced Supported "Microtubules,Cytokinetic bridge" Yes NA "Cluster 49: Eosinophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Microtubules, Cytokinetic bridge" "HPA031473: AB_2673901, HPA031474: AB_10600109, HPA031475: AB_10600442" "unprognostic (1.67e-1)" "unprognostic (3.07e-1)" "unprognostic (1.96e-1)" "unprognostic (3.33e-3)" "unprognostic (1.00e-1)" "unprognostic (1.22e-2)" "unprognostic (2.79e-1)" "unprognostic (1.35e-1)" "unprognostic (2.87e-1)" "unprognostic (4.97e-2)" "unprognostic (1.30e-3)" "unprognostic (3.45e-2)" "unprognostic (3.91e-5)" "unprognostic (2.51e-2)" "unprognostic (5.46e-2)" "unprognostic (5.93e-2)" "unprognostic (9.62e-2)" 0.2 0.2 0.4 0.1 1.7 0.1 0.1 1.2 9.7 0.6 1.8 0.9 0.1 1.5 0.0 0.3 0.8 0.1 50.2 1.0 0.0 0.1 0.9 0.1 0.6 0.0 0.1 7.5 4.8 0.0 6.1 0.0 0.0 0.3 0.2 4.6 1.0 0.1 0.1 0.2 0.4 1.2 2.2 0.5 1.3 1.2 1.0 0.2 0.5 0.1 0.1 1.3 0.2 2.4 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.2 13.2 0.4 0.0 0.0 0.0 0.5 0.0 5.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 1.0 0.0 2.3 1.6 0.1 0.4 0.0 0.2 0.2 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.7 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 1.7 1.2 9.7 1.0 0.0 0.0 0.1 0.0 2.2 1.0 2.4 0.1 0.0 0.5 10.4 0.1 0.5 0.7 0.1 0.0 0.0 0.3 0.4 145.8 0.0 1.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 5.4 0.3 1.0 0.7 0.0 0.8 548.4 0.6 0.0 5.9 0.0 1.1 0.0 1.2 0.4 0.5 0.1 0.0 671.8 0.7 0.0 0.0 0.8 3.3 0.9 0.2 1.8 15.0 0.1 0.0 0.0 18.1 16.2 0.4 0.0 0.0 0.1 0.2 0.0 0.0 3.6 0.0 0.0 1.6 1.0 0.1 4.1 1.8 0.1 0.3 0.3 19.6 0.0 1.1 MXI1 "bHLHc11, MAD2, MXD2, MXI" ENSG00000119950 "MAX interactor 1, dimerization protein" P50539 10 110207605-110287365 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 264.7;Oligodendrocytes: 214.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 108.2;SK-MEL-30: 167.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035319, HPA035320, HPA056762" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nucleoli, Nucleoli rim, Cytosol" "HPA035319: AB_10670588, HPA035320: , HPA056762: AB_2683229" "unprognostic (1.77e-2)" "unprognostic (2.02e-1)" "unprognostic (3.34e-1)" "unprognostic (3.03e-2)" "unprognostic (1.11e-1)" "unprognostic (1.71e-2)" "unprognostic (1.08e-2)" "unprognostic (1.03e-1)" "unprognostic (1.37e-2)" "unprognostic (1.59e-1)" "unprognostic (9.26e-3)" "prognostic unfavorable (9.17e-4)" "prognostic unfavorable (1.02e-5)" "unprognostic (3.05e-2)" "unprognostic (1.36e-2)" "unprognostic (2.29e-1)" "unprognostic (2.96e-1)" 34.0 32.7 86.8 13.2 98.0 68.0 45.1 92.9 106.1 38.8 67.0 55.9 24.4 45.6 36.2 52.3 42.4 32.8 63.2 84.9 91.1 39.2 51.1 26.4 13.8 93.9 91.8 81.4 44.7 50.6 22.1 28.5 94.7 41.0 35.0 80.2 80.1 52.1 47.3 47.6 29.6 29.8 89.3 14.8 28.0 23.3 94.9 31.2 54.5 53.2 12.3 34.6 41.2 110.8 18.2 8.3 18.0 39.6 30.7 21.4 7.4 11.1 39.2 7.1 23.1 3.2 33.5 24.6 17.6 20.0 11.3 24.3 23.5 27.8 20.0 13.5 30.9 7.3 15.7 14.5 19.5 14.3 14.4 21.7 96.0 12.4 55.2 108.2 7.1 17.5 26.9 54.9 11.3 12.3 10.1 26.1 7.7 31.0 21.2 6.1 26.0 39.9 22.8 1.6 34.3 52.4 11.1 7.3 167.1 23.3 9.9 42.2 7.7 13.5 21.0 13.6 5.6 44.6 26.1 10.0 34.3 46.1 12.7 1.8 2.7 9.7 2.7 2.3 5.1 3.9 5.1 2.8 1.6 3.6 7.7 1.9 5.6 1.4 5.0 1.7 4.8 2.0 86.8 98.0 92.9 106.1 84.9 91.1 93.9 91.8 94.7 89.3 94.9 110.8 28.9 16.0 16.8 139.1 27.9 58.0 57.9 22.8 51.2 49.9 67.2 66.8 80.2 41.5 27.6 33.1 47.9 5.4 23.0 160.7 46.9 19.3 5.1 29.1 36.4 34.1 16.9 264.7 60.8 14.8 20.1 36.0 15.8 37.3 3.8 19.1 27.8 56.6 11.1 52.2 102.5 20.1 18.3 24.1 20.5 8.8 45.1 22.6 104.9 30.9 29.9 144.2 9.2 131.7 214.9 10.4 52.5 55.7 22.5 73.4 57.0 67.1 25.3 46.0 46.0 69.6 63.0 23.8 28.2 37.4 67.3 9.7 36.9 27.4 16.6 36.9 MYBL2 "B-MYB, BMYB" ENSG00000101057 "MYB proto-oncogene like 2" P10244 20 43667019-43716495 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 91.8;lymphoid tissue: 55.5" "Cell type enhanced" "Detected in many" "B-cells: 33.0;dendritic cells: 32.6;Erythroid cells: 82.3;Extravillous trophoblasts: 32.3;Plasma cells: 139.6;Spermatogonia: 33.6" "Cancer enriched" "Detected in all" 5 "testis cancer: 295.8" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 34 "plasmacytoid DC: 91.5" "Lineage enriched" "Detected in many" 34 "dendritic cells: 91.5" "Cell line enhanced" "Detected in many" "MCF7: 763.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017114, HPA030530, HPA055416" Uncertain Supported Nucleoplasm,Cytosol Yes Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm Cytosol "CAB017114: , HPA030530: AB_2673515, HPA055416: AB_2682811" "unprognostic (9.75e-3)" "unprognostic (1.29e-2)" "unprognostic (3.20e-1)" "prognostic unfavorable (9.73e-4)" "unprognostic (2.35e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (2.11e-7)" "unprognostic (2.66e-3)" "unprognostic (9.23e-3)" "unprognostic (1.78e-1)" "unprognostic (2.38e-3)" "unprognostic (1.32e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.42e-1)" "unprognostic (2.27e-1)" "unprognostic (1.19e-1)" "unprognostic (1.84e-1)" 1.6 0.6 0.1 24.2 0.1 91.8 1.6 0.1 0.2 1.1 0.2 8.6 7.0 1.4 0.1 10.1 0.4 1.0 0.4 0.1 0.1 0.6 1.1 1.8 55.5 0.1 0.1 0.3 11.2 0.1 0.2 5.7 0.1 0.5 6.9 0.0 1.6 0.2 0.1 4.2 7.8 2.1 0.1 27.8 6.1 15.6 0.4 33.3 0.5 0.0 53.5 3.5 2.5 0.1 195.8 121.8 105.4 109.6 1.0 3.5 136.2 87.0 29.0 265.6 194.6 600.2 118.8 393.6 49.2 37.8 55.8 116.1 192.1 59.6 98.8 74.2 124.1 183.2 118.7 164.2 0.2 168.6 121.7 2.4 5.1 101.6 22.9 5.9 72.2 189.6 188.1 470.3 23.8 763.7 346.0 236.3 121.8 155.4 105.4 237.3 216.3 222.1 49.6 39.7 96.7 140.6 255.6 253.3 26.1 110.4 167.2 183.1 34.0 16.3 264.3 118.3 151.5 162.1 363.8 606.5 34.2 142.3 103.9 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.3 0.0 1.4 0.0 0.0 0.1 0.2 0.0 91.5 1.3 0.8 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.2 0.0 0.0 0.0 33.0 4.2 0.8 0.8 0.0 0.0 2.5 3.4 2.0 1.5 0.1 0.0 0.0 14.4 32.6 3.4 0.0 0.4 5.9 0.9 1.3 1.8 0.0 82.3 0.4 0.9 32.3 4.8 10.2 2.9 0.0 18.9 0.7 1.4 13.5 0.0 0.3 5.1 0.0 2.4 2.6 14.1 0.0 3.2 1.8 0.0 0.0 0.0 1.0 0.0 0.5 0.7 1.1 0.0 139.6 0.3 0.5 0.0 0.0 0.0 0.0 0.1 3.9 7.0 33.6 8.2 2.4 3.7 3.0 1.2 8.6 2.4 MYCL "bHLHe38, LMYC, MYCL1" ENSG00000116990 "MYCL proto-oncogene, bHLH transcription factor" P12524 1 39895426-39902256 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 67.8;skin 1: 41.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 34.9;Hepatocytes: 24.3;Intestinal goblet cells: 25.0;monocytes: 27.4;Squamous epithelial cells: 34.2;Urothelial cells: 27.1" "Cancer enhanced" "Detected in all" "urothelial cancer: 28.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 17.3;intermediate monocyte: 8.2;myeloid DC: 18.7;plasmacytoid DC: 22.8" "Group enriched" "Detected in many" 72 "dendritic cells: 22.8;monocytes: 17.3" "Group enriched" "Detected in many" 7 "U-266/70: 444.0;U-266/84: 364.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA063132, HPA074515" Enhanced "Nucleoplasm,Mitotic chromosome" Yes NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 29: U-266 - Adaptive immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Mitotic chromosome" "HPA063132: AB_2684946, HPA074515: " "unprognostic (7.45e-2)" "unprognostic (6.91e-2)" "unprognostic (7.36e-2)" "unprognostic (1.83e-3)" "unprognostic (1.61e-2)" "unprognostic (2.92e-3)" "unprognostic (6.72e-3)" "prognostic favorable (4.49e-4)" "unprognostic (1.24e-1)" "unprognostic (1.77e-2)" "unprognostic (5.44e-2)" "unprognostic (1.12e-1)" "unprognostic (5.01e-3)" "unprognostic (2.75e-2)" "unprognostic (5.21e-2)" "unprognostic (1.53e-2)" "unprognostic (5.80e-2)" 0.8 0.3 1.8 4.7 2.0 0.6 3.3 1.2 2.0 5.2 1.8 6.1 4.8 0.9 7.2 22.1 3.1 1.5 0.5 2.2 1.7 1.5 11.4 3.3 6.4 1.5 1.5 0.3 67.8 0.3 2.9 6.7 1.6 4.2 6.7 0.2 6.4 7.5 0.5 41.5 5.7 1.1 1.9 7.6 6.2 1.3 2.0 6.5 5.3 0.5 9.5 15.9 12.8 1.6 1.2 0.4 14.4 3.5 0.2 0.1 31.8 0.5 0.2 1.0 0.7 0.4 0.8 2.2 1.4 0.1 0.4 3.3 10.4 2.7 0.8 2.0 4.9 0.5 0.3 0.5 0.4 0.3 7.5 1.0 12.1 0.4 1.3 0.2 1.2 5.4 3.2 0.4 0.6 1.2 0.2 0.3 13.4 2.2 0.4 1.3 15.5 2.9 1.1 58.0 2.5 3.1 1.4 2.1 0.8 5.5 3.7 18.7 0.0 0.0 4.6 6.2 0.5 444.0 364.6 1.0 0.1 2.3 0.3 0.0 17.3 0.0 0.0 8.2 0.0 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.2 0.0 3.4 22.8 0.0 6.7 1.8 2.0 1.2 2.0 2.2 1.7 1.5 1.5 1.6 1.9 2.0 1.6 0.4 0.0 1.1 0.0 0.8 6.6 10.0 2.1 13.1 0.4 3.8 6.0 3.7 0.0 5.5 9.2 0.0 34.9 20.1 13.4 0.0 1.5 0.1 5.1 0.6 0.5 17.3 0.0 0.2 5.8 15.4 0.9 5.1 6.3 0.0 0.0 1.4 24.3 5.1 0.0 0.3 25.0 8.2 8.3 13.1 0.4 0.0 10.6 1.8 0.0 27.4 0.8 0.0 1.0 0.0 2.9 6.5 0.0 3.6 5.3 6.4 0.1 4.9 0.1 0.0 1.4 0.7 0.0 1.2 34.2 11.8 17.5 0.3 0.0 10.8 27.1 MYOM3 FLJ35961 ENSG00000142661 "Myomesin 3" Q5VTT5 1 24056035-24112135 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "heart muscle: 222.5;skeletal muscle: 321.5;tongue: 255.9" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 198.3" "Cancer enhanced" "Detected in some" "renal cancer: 6.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "A549: 4.6;Hep G2: 18.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA028132, HPA028340" Approved "Golgi apparatus,Vesicles,Cytokinetic bridge" Yes No 830000 "Cluster 38: Heart - Muscle contraction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Vesicles "Golgi apparatus, Cytokinetic bridge" "HPA028132: AB_10599293, HPA028340: " "unprognostic (8.59e-2)" "unprognostic (2.85e-2)" "unprognostic (2.39e-1)" "unprognostic (8.60e-3)" "unprognostic (1.52e-2)" "unprognostic (7.31e-2)" "unprognostic (3.00e-2)" "unprognostic (1.40e-2)" "unprognostic (4.66e-1)" "unprognostic (2.21e-1)" "unprognostic (2.73e-4)" "unprognostic (2.09e-1)" "prognostic favorable (4.28e-6)" "unprognostic (2.77e-2)" "unprognostic (1.60e-3)" "unprognostic (7.75e-2)" "unprognostic (1.68e-1)" 0.4 0.2 0.0 0.2 0.0 0.0 0.7 0.3 0.1 0.2 0.0 0.6 1.1 0.3 0.0 6.0 0.9 0.4 222.5 0.1 0.1 31.4 0.2 0.3 0.1 0.1 0.1 0.1 1.2 0.0 0.0 0.0 0.1 4.5 0.7 1.2 7.1 0.0 321.5 2.2 5.2 0.2 0.0 0.0 0.2 9.0 0.0 1.7 0.3 255.9 0.1 0.1 0.4 0.2 0.1 4.6 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 1.3 0.0 1.9 0.6 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.8 18.1 0.0 0.1 0.1 0.5 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.4 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.2 0.2 0.1 1.0 0.2 0.5 0.6 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 1.0 0.6 0.2 0.1 0.6 0.0 0.1 0.6 198.3 0.0 0.0 3.7 0.0 0.0 0.1 3.6 1.9 0.1 16.2 0.4 0.0 1.6 1.2 0.0 0.4 0.4 0.0 6.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.3 1.7 0.0 0.0 0.7 10.3 0.6 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.2 2.5 2.4 0.0 0.0 0.2 13.0 33.2 0.0 2.5 6.6 10.0 1.3 0.0 0.2 0.0 0.6 0.0 0.3 2.3 2.2 0.3 N6AMT1 "C21orf127, HEMK2, KMT9, MTQ2, N6AMT, PRED28, PrmC" ENSG00000156239 "N-6 adenine-specific DNA methyltransferase 1" Q9Y5N5 21 28872191-28885371 "Metabolic proteins, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034133, CAB034135, HPA059242" Approved Approved Nucleoplasm,Centrosome Yes No "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" Centrosome Nucleoplasm "CAB034133: AB_2147189, CAB034135: AB_2250945, HPA059242: AB_2683957" "unprognostic (2.20e-2)" "unprognostic (4.93e-2)" "unprognostic (5.06e-2)" "unprognostic (2.82e-1)" "unprognostic (7.46e-2)" "unprognostic (1.56e-1)" "unprognostic (1.09e-1)" "unprognostic (3.67e-1)" "unprognostic (2.64e-1)" "unprognostic (1.04e-1)" "unprognostic (1.94e-2)" "unprognostic (2.67e-1)" "unprognostic (1.03e-1)" "unprognostic (5.24e-2)" "unprognostic (6.99e-2)" "unprognostic (5.43e-2)" "unprognostic (5.51e-3)" 2.4 5.0 4.9 2.5 5.6 0.9 5.0 4.8 5.3 6.2 4.8 3.4 3.2 6.4 6.1 2.5 4.7 2.8 5.3 4.5 5.3 4.9 2.8 2.5 3.4 5.7 5.0 7.9 2.9 5.7 4.4 6.4 5.6 4.6 3.4 8.4 3.1 4.0 6.1 3.8 2.8 3.5 4.7 3.6 3.1 3.7 5.0 2.2 5.3 5.6 3.3 3.9 4.1 8.8 2.8 2.5 6.2 8.6 5.1 5.6 4.8 6.1 2.5 3.5 2.0 3.2 5.0 3.1 3.0 3.3 6.2 3.3 5.4 3.0 4.3 4.0 4.1 6.7 4.2 4.0 4.5 4.0 2.5 2.9 6.4 3.5 2.4 6.3 2.6 3.8 8.4 5.5 7.3 2.9 1.9 3.2 7.9 6.0 3.5 2.8 5.9 2.4 6.0 4.1 4.7 6.6 5.5 1.9 2.3 5.6 2.7 3.5 5.4 2.9 5.2 5.4 3.7 3.3 4.0 1.7 4.6 10.4 5.5 0.3 0.4 0.6 0.5 0.7 0.6 0.7 1.0 0.7 0.6 0.6 1.4 1.0 0.1 1.4 0.5 0.5 0.4 0.5 4.9 5.6 4.8 5.3 4.5 5.3 5.7 5.0 5.6 4.7 5.0 8.8 7.8 3.2 5.4 5.2 7.1 1.9 5.8 10.3 1.8 10.8 6.3 6.5 17.0 7.2 8.7 12.9 8.4 18.3 4.0 1.5 7.9 11.0 2.9 10.7 9.6 6.9 0.0 13.0 4.6 6.4 12.2 7.9 8.6 4.2 1.3 15.1 5.3 3.5 7.2 10.1 5.1 3.0 10.2 1.3 0.9 4.5 9.6 2.6 1.8 1.0 2.7 11.1 4.1 6.6 15.1 7.7 4.3 10.1 1.2 4.5 2.5 9.3 15.8 10.5 0.0 7.7 8.9 4.5 10.5 4.2 3.7 14.9 5.1 20.1 3.1 4.8 NAT10 "FLJ10774, FLJ12179, hALP, KIAA1709, Kre33, NET43" ENSG00000135372 "N-acetyltransferase 10" Q9H0A0 11 34105617-34147670 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB035546, HPA057576, HPA071628" Approved Enhanced Nucleoli,Midbody Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoli Midbody "CAB035546: , HPA057576: AB_2683475, HPA071628: AB_2686426" "unprognostic (3.04e-1)" "unprognostic (9.24e-2)" "unprognostic (2.46e-1)" "unprognostic (1.14e-1)" "unprognostic (1.92e-2)" "prognostic unfavorable (1.07e-4)" "prognostic unfavorable (9.61e-8)" "unprognostic (1.15e-1)" "unprognostic (2.57e-1)" "unprognostic (2.24e-1)" "unprognostic (1.12e-2)" "unprognostic (2.25e-1)" "prognostic unfavorable (8.83e-5)" "unprognostic (1.24e-1)" "unprognostic (7.18e-2)" "unprognostic (9.55e-2)" "unprognostic (8.69e-2)" 20.6 24.2 16.0 17.3 15.4 20.4 19.6 14.7 17.4 20.1 14.0 17.0 10.2 20.0 13.7 25.7 19.2 9.4 18.4 15.1 15.4 19.5 22.3 14.9 23.4 14.3 13.6 23.1 25.3 16.8 17.5 15.1 14.7 19.4 15.5 16.3 16.7 12.2 24.8 28.9 17.5 15.5 12.6 22.8 18.7 22.0 15.6 19.4 17.2 12.5 27.5 20.3 20.5 16.9 40.0 55.5 29.3 62.0 34.2 30.2 33.6 38.8 28.5 48.4 38.4 62.6 22.6 127.6 28.3 33.0 41.8 59.5 110.5 59.4 59.5 35.9 70.2 58.0 44.5 58.9 31.0 147.3 40.7 31.1 40.0 31.5 88.3 22.8 37.4 60.6 128.6 43.5 40.8 76.0 120.5 65.7 41.9 69.3 65.7 89.3 98.0 53.7 27.8 68.5 43.1 32.6 52.3 54.9 23.6 28.2 55.0 41.0 30.5 42.8 34.0 63.7 72.8 47.0 61.0 120.3 43.3 60.0 43.4 0.7 8.3 2.8 11.7 13.7 15.5 12.2 12.6 13.4 15.5 10.6 12.7 13.2 0.9 15.0 12.9 11.6 12.0 9.1 16.0 15.4 14.7 17.4 15.1 15.4 14.3 13.6 14.7 12.6 15.6 16.9 8.5 6.4 20.7 10.4 12.7 12.2 11.3 6.9 12.5 12.2 8.8 10.2 12.6 7.2 15.1 14.7 12.5 18.1 8.0 5.8 5.9 9.2 6.1 10.1 18.3 10.9 7.2 21.0 22.8 9.6 13.4 14.5 5.6 12.2 5.1 17.3 5.7 7.5 12.0 11.8 21.7 8.9 4.1 5.5 4.4 3.4 9.3 8.5 1.8 6.5 12.9 5.3 7.2 11.6 16.0 8.7 3.5 13.2 9.8 14.8 3.7 5.8 10.6 11.0 13.1 19.6 8.4 20.5 21.6 13.1 13.8 14.4 11.0 19.7 14.3 7.6 NCAPH "BRRN1, CAP-H, hCAP-H" ENSG00000121152 "Non-SMC condensin I complex subunit H" Q15003 2 96335766-96377091 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.2;lymphoid tissue: 37.4;testis: 35.4" "Cell type enhanced" "Detected in many" "Plasma cells: 26.3;Spermatocytes: 89.3;Spermatogonia: 29.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "T-reg: 6.2" "Group enriched" "Detected in many" 5 "granulocytes: 3.8;T-cells: 6.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA002647, HPA003008" Enhanced Supported Nucleoplasm,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol Nucleoplasm "HPA002647: AB_1078300, HPA003008: AB_1078301" "unprognostic (5.52e-2)" "unprognostic (7.37e-2)" "unprognostic (2.93e-2)" "unprognostic (2.85e-3)" "unprognostic (1.92e-1)" "unprognostic (7.51e-2)" "prognostic unfavorable (9.53e-6)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.50e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.16e-2)" "unprognostic (0.00e+0)" "unprognostic (3.00e-2)" "unprognostic (2.38e-1)" "unprognostic (2.14e-1)" "unprognostic (2.30e-2)" 1.2 0.7 0.3 9.9 0.4 35.2 1.8 0.9 0.9 1.3 0.1 7.7 5.6 0.9 0.2 6.3 0.5 1.6 0.4 0.3 0.2 0.4 1.0 1.1 20.3 0.1 0.0 0.3 0.3 0.5 0.2 5.2 0.3 0.4 9.3 1.8 1.5 0.2 0.3 4.7 6.2 2.8 0.0 3.7 3.6 35.4 0.1 37.4 0.4 0.1 22.0 2.6 2.0 0.3 134.1 52.0 115.1 60.6 3.9 6.1 80.8 58.7 40.3 115.1 118.4 93.5 71.5 121.0 41.8 26.6 106.2 57.2 100.2 39.6 117.2 110.0 63.4 123.7 49.3 74.5 0.7 112.2 101.3 1.8 4.2 89.1 35.9 10.2 46.6 89.7 89.5 88.8 53.0 59.5 183.8 104.2 85.9 57.6 56.6 133.4 106.7 95.5 23.6 49.6 71.2 52.3 34.8 46.5 19.9 42.4 36.6 80.0 24.1 83.5 126.3 76.9 101.9 44.4 70.1 134.0 33.7 111.5 95.3 3.8 0.0 0.2 0.8 0.9 0.1 0.9 1.2 1.0 0.4 0.9 0.0 0.4 0.3 0.1 0.0 0.0 6.2 0.5 0.3 0.4 0.9 0.9 0.3 0.2 0.1 0.0 0.3 0.0 0.1 0.3 4.9 0.0 0.0 0.0 3.5 0.6 0.7 1.9 1.2 0.4 1.0 0.8 0.5 0.0 1.6 0.0 8.4 9.4 2.0 2.1 0.0 0.5 5.9 1.7 0.9 1.8 0.0 16.4 0.4 0.0 16.3 1.8 4.1 1.2 1.3 5.5 1.4 0.4 8.5 0.0 0.3 2.8 0.0 3.8 3.7 4.9 0.9 2.2 1.8 0.0 0.2 8.5 0.0 0.5 1.0 0.2 0.1 0.4 26.3 0.7 0.4 0.0 1.6 2.3 0.0 0.2 3.5 89.3 29.4 8.8 0.9 1.9 5.1 0.6 5.7 1.1 NCAPH2 "384D8-2, CAP-H2, hCAP-H2" ENSG00000025770 "Non-SMC condensin II complex subunit H2" Q6IBW4 22 50508224-50524780 "Predicted intracellular proteins" "DNA condensation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067932, HPA069056" Enhanced Supported "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 46: Basophils - DNA binding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cytokinetic bridge" "HPA067932: AB_2685926, HPA069056: AB_2686076" "unprognostic (2.01e-1)" "prognostic favorable (2.24e-8)" "unprognostic (3.65e-2)" "unprognostic (2.81e-1)" "unprognostic (5.04e-2)" "unprognostic (1.57e-2)" "prognostic unfavorable (8.25e-4)" "unprognostic (2.92e-2)" "unprognostic (8.66e-2)" "unprognostic (1.10e-1)" "unprognostic (2.26e-2)" "unprognostic (6.31e-2)" "unprognostic (2.04e-3)" "unprognostic (2.64e-2)" "unprognostic (1.80e-1)" "unprognostic (1.41e-1)" "unprognostic (3.00e-1)" 25.7 21.9 32.9 24.5 33.6 78.8 26.9 32.7 39.2 31.8 25.4 29.3 17.7 29.8 12.4 30.3 30.0 13.0 36.7 32.0 30.9 26.6 27.6 28.2 27.6 32.6 29.0 37.6 40.7 16.7 38.6 17.1 28.7 28.4 11.7 15.5 25.7 16.6 30.7 32.6 28.4 14.7 27.5 33.2 30.2 52.3 28.5 29.6 28.9 19.3 20.2 25.9 26.9 33.5 60.7 32.1 53.8 57.1 15.8 18.4 71.6 45.8 31.6 81.8 89.5 67.2 41.4 68.8 25.5 32.9 45.5 47.1 49.0 44.2 23.5 40.3 82.8 39.8 86.7 63.6 19.1 90.3 69.5 16.1 27.6 64.4 22.2 12.2 26.2 59.4 51.5 132.5 33.4 83.9 61.7 109.9 39.3 34.9 37.9 103.3 71.0 77.2 23.8 40.6 35.6 47.5 36.7 55.4 44.3 16.5 37.5 86.7 17.6 64.2 80.5 54.4 72.3 67.7 45.8 110.1 48.8 45.7 62.3 11.9 9.8 18.2 18.7 11.6 22.9 16.0 19.4 19.1 8.0 14.2 19.9 17.3 11.4 13.9 14.4 11.8 19.3 15.5 32.9 33.6 32.7 39.2 32.0 30.9 32.6 29.0 28.7 27.5 28.5 33.5 10.1 22.4 24.5 12.1 15.9 18.9 23.8 17.5 6.2 18.3 11.5 12.6 19.6 15.7 10.4 9.2 4.2 36.3 15.5 24.6 15.6 16.6 36.8 8.5 7.5 12.9 13.1 31.5 8.6 23.5 55.1 13.8 14.8 14.5 17.1 16.3 8.9 10.6 19.3 8.4 8.8 18.8 6.1 7.9 16.3 111.5 17.4 9.2 12.4 3.7 16.2 14.7 18.6 3.0 8.2 17.3 13.5 17.3 26.6 15.2 18.4 9.5 5.9 16.1 19.7 17.8 16.9 36.2 39.7 10.9 18.5 31.5 15.9 7.6 22.6 18.2 NCL "C23, Nsr1" ENSG00000115053 Nucleolin P19338 2 231453531-231483641 "Plasma proteins, Predicted intracellular proteins" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004210, HPA023981, HPA071110" Supported Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 1400000 "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli, Nucleoli rim" "Mitotic chromosome" "CAB004210: AB_670270, HPA023981: AB_1854688, HPA071110: " "unprognostic (1.91e-1)" "unprognostic (2.53e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.28e-4)" "unprognostic (1.63e-2)" "unprognostic (2.72e-3)" "prognostic unfavorable (1.41e-6)" "unprognostic (3.74e-2)" "unprognostic (4.31e-3)" "unprognostic (9.78e-2)" "unprognostic (6.70e-3)" "unprognostic (6.07e-2)" "unprognostic (1.66e-2)" "unprognostic (2.57e-2)" "unprognostic (9.70e-2)" "unprognostic (2.84e-2)" "unprognostic (1.42e-2)" 212.0 192.8 128.8 226.0 146.3 301.4 228.7 129.1 139.6 180.0 114.1 183.6 160.7 205.2 150.2 228.8 173.2 132.2 164.3 115.9 152.3 166.2 218.5 147.4 289.7 148.8 141.5 258.2 209.0 258.9 115.9 203.4 140.4 155.4 219.2 147.1 157.0 160.9 350.9 197.1 157.4 201.0 137.9 176.3 164.7 126.2 142.1 347.0 198.4 228.2 329.0 271.1 169.1 143.9 718.3 691.8 715.7 640.1 485.7 592.0 823.0 790.4 497.2 690.8 628.2 1227.4 521.4 1083.7 608.6 651.0 892.6 719.5 1614.4 1059.9 1284.7 554.6 644.0 1587.3 605.9 1749.5 544.0 1930.4 632.7 513.5 613.2 872.3 1019.6 394.9 834.2 770.5 1745.4 378.6 760.5 1176.4 1443.2 1086.7 1202.0 728.7 435.9 1290.8 1452.0 918.4 583.8 959.9 749.0 502.0 555.8 704.5 706.9 625.7 476.8 985.3 686.3 611.4 626.7 714.5 1063.7 624.3 554.5 1885.9 467.2 1173.1 685.2 27.3 95.6 62.5 136.5 100.3 152.8 113.5 118.4 121.9 130.6 111.9 130.3 114.2 16.8 177.8 121.7 102.0 102.3 151.0 128.8 146.3 129.1 139.6 115.9 152.3 148.8 141.5 140.4 137.9 142.1 143.9 286.2 291.7 411.7 8.1 468.9 459.9 633.8 241.0 644.9 145.0 315.2 303.8 320.9 147.3 401.6 195.0 47.9 386.9 596.2 215.0 230.9 294.4 20.6 348.7 669.8 291.1 200.0 419.2 9.3 254.4 444.6 370.9 292.0 421.8 451.7 262.7 130.6 242.0 239.5 80.8 10.4 319.6 156.6 133.7 231.1 32.2 217.2 281.8 165.4 10.3 268.9 199.6 346.1 14.1 14.9 268.0 153.9 159.9 543.5 651.1 120.1 277.6 250.3 141.0 151.2 548.9 442.0 433.3 532.4 707.9 441.4 379.0 454.0 442.6 380.6 449.1 NEFL "CMT1F, CMT2E, NF68, NFL, PPP1R110" ENSG00000277586 "Neurofilament light" P07196 8 24950955-24956721 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 675.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 32.7;Distal tubular cells: 103.7;Enteroendocrine cells: 33.3;Excitatory neurons: 64.6;Horizontal cells: 30.3;Rod photoreceptor cells: 110.0" "Cancer enhanced" "Detected in many" "renal cancer: 24.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "memory CD4 T-cell: 11.2" "Lineage enriched" "Detected in single" 113 "T-cells: 11.2" "Group enriched" "Detected in some" 4 "HEK 293: 456.2;PC-3: 145.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014850, HPA015021" Enhanced Supported Approved "Nucleoplasm,Intermediate filaments,Midbody" Yes NA 200000 "Cluster 32: T-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Intermediate filaments" Midbody "HPA014850: AB_1854397, HPA015021: AB_2669135" "unprognostic (7.63e-2)" "unprognostic (1.36e-2)" "unprognostic (9.53e-2)" "unprognostic (6.81e-2)" "unprognostic (2.82e-2)" "unprognostic (6.69e-2)" "unprognostic (3.69e-2)" "unprognostic (3.78e-3)" "unprognostic (3.06e-1)" "unprognostic (1.60e-1)" "unprognostic (1.46e-2)" "unprognostic (1.94e-1)" "prognostic unfavorable (4.91e-4)" "unprognostic (5.76e-3)" "unprognostic (7.88e-2)" "unprognostic (3.97e-3)" "unprognostic (3.17e-3)" 0.1 18.0 35.4 1.3 36.7 0.0 0.0 103.6 675.9 2.0 0.0 2.5 0.6 0.1 0.3 5.4 1.3 0.1 0.1 50.9 75.6 5.0 0.0 0.0 0.1 425.7 41.1 0.2 0.2 0.1 4.0 0.0 231.3 1.8 1.5 89.5 0.0 15.6 0.0 0.9 1.9 1.1 33.9 0.2 0.8 1.7 216.1 12.7 0.7 0.1 0.3 0.0 1.4 184.0 0.0 0.6 68.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.7 0.0 0.6 0.0 0.0 456.2 0.0 0.0 0.0 21.6 0.0 1.0 8.3 2.0 0.1 1.4 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.0 18.8 0.0 145.4 0.0 0.0 0.0 31.7 4.2 30.9 31.6 11.2 0.0 1.9 2.2 0.0 0.0 0.0 2.2 31.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 4.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.2 1.2 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.2 1.5 35.4 36.7 103.6 675.9 50.9 75.6 425.7 41.1 231.3 33.9 216.1 184.0 0.1 0.0 0.0 23.2 0.0 0.0 0.0 0.0 0.6 32.7 0.0 0.0 3.2 0.0 0.0 0.0 8.4 0.0 0.1 0.1 103.7 0.1 0.4 0.1 0.3 3.7 33.3 0.0 64.6 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 30.3 29.1 0.1 0.0 0.0 0.0 0.7 0.0 0.2 0.0 27.2 0.1 27.8 0.0 14.6 18.4 0.0 0.1 9.4 0.0 0.0 0.0 0.2 0.0 110.0 0.0 0.1 0.2 0.0 13.2 1.5 0.0 0.0 1.6 1.4 0.0 0.0 NEFM "NEF3, NF-M, NFM" ENSG00000104722 "Neurofilament medium" P07197 8 24913758-24919098 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 689.9" "Cell type enhanced" "Detected in many" "Early spermatids: 92.6;Excitatory neurons: 46.6;Late spermatids: 114.6;Rod photoreceptor cells: 69.1;Spermatocytes: 43.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 25 "HEK 293: 3890.8" "CAB010900, CAB012976, HPA022845, HPA023138" Enhanced Enhanced "Intermediate filaments" Yes NA 220000 "Cluster 70: Brain - Nervous system development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "Intermediate filaments" "CAB010900: AB_477261, CAB012976: AB_2533154, HPA022845: AB_1854399, HPA023138: AB_1854398" "unprognostic (1.41e-2)" "unprognostic (1.83e-1)" "unprognostic (2.59e-2)" "unprognostic (9.38e-2)" "unprognostic (5.17e-2)" "unprognostic (6.32e-3)" "unprognostic (6.10e-3)" "unprognostic (2.57e-1)" "unprognostic (8.55e-3)" "unprognostic (2.95e-2)" "unprognostic (1.84e-1)" "unprognostic (1.69e-2)" "unprognostic (1.38e-2)" "unprognostic (1.92e-1)" "unprognostic (4.76e-2)" "unprognostic (2.61e-2)" 0.3 19.5 61.1 0.9 27.9 0.0 0.1 150.0 689.9 9.6 0.0 2.8 0.1 4.0 0.0 4.0 5.3 0.2 0.2 57.7 54.0 1.9 0.1 0.2 0.1 610.3 89.1 1.7 2.0 0.0 17.9 0.2 487.1 1.5 0.7 90.8 0.3 27.6 1.7 0.6 1.3 2.5 86.8 0.1 0.9 18.9 430.5 1.7 0.1 0.7 0.5 0.4 6.5 203.6 0.0 0.0 154.3 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3890.8 0.0 0.0 0.0 79.4 0.0 0.1 2.4 0.1 0.6 0.0 0.0 0.0 0.7 0.0 0.2 5.9 0.0 0.0 0.0 30.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 3.7 32.6 0.0 0.0 0.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.1 27.9 150.0 689.9 57.7 54.0 610.3 89.1 487.1 86.8 430.5 203.6 3.1 0.0 0.0 12.4 0.0 1.3 0.2 0.1 9.1 30.9 1.1 21.2 2.4 0.0 0.6 0.0 6.2 0.0 3.2 0.1 0.0 0.1 92.6 0.7 19.5 2.9 3.5 0.0 46.6 0.2 0.0 2.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 20.2 17.5 0.0 0.0 0.0 0.7 114.6 0.9 0.7 1.8 13.1 0.0 22.8 0.0 9.5 13.6 0.0 0.0 4.5 0.4 0.3 0.0 0.4 0.0 69.1 0.0 3.3 5.7 43.8 1.0 14.0 0.3 0.0 4.1 0.0 0.1 0.4 NEK7 ENSG00000151414 "NIMA related kinase 7" Q8TDX7 1 198156994-198322420 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 140.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 172.6;Oligodendrocyte precursor cells: 131.2;Oligodendrocytes: 153.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ: 554.5;fHDF/TERT166: 753.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015520, HPA018193" Approved Supported Nucleoplasm Yes No "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA015520: AB_1854371, HPA018193: AB_1854372" "unprognostic (2.08e-1)" "unprognostic (2.98e-2)" "unprognostic (1.65e-1)" "unprognostic (5.38e-2)" "unprognostic (4.26e-2)" "unprognostic (3.00e-2)" "unprognostic (2.14e-2)" "unprognostic (5.47e-2)" "unprognostic (4.77e-2)" "unprognostic (3.21e-1)" "unprognostic (1.46e-3)" "unprognostic (2.82e-1)" "unprognostic (1.13e-2)" "unprognostic (1.26e-2)" "unprognostic (1.74e-1)" "unprognostic (2.05e-2)" "unprognostic (1.56e-1)" 63.8 49.9 48.3 29.3 58.7 11.1 27.7 45.9 53.3 26.1 35.7 30.0 21.1 26.6 19.7 31.2 22.3 27.2 140.4 39.5 56.1 29.3 30.0 41.6 30.8 61.1 51.3 29.6 20.3 25.1 12.3 42.1 60.0 27.1 23.3 19.6 22.3 36.5 56.6 14.9 25.3 32.2 59.7 32.1 20.1 13.7 49.1 27.7 26.8 63.7 23.6 30.9 20.1 64.2 47.8 12.3 14.8 6.0 37.5 42.6 17.4 554.5 227.6 218.7 102.9 23.0 46.2 17.1 39.4 753.3 12.6 29.0 22.7 30.3 220.8 56.0 32.7 23.6 48.7 9.6 45.3 40.2 46.3 26.7 25.3 144.8 43.5 82.2 42.4 140.0 18.8 41.2 102.3 15.1 34.7 23.4 8.4 37.5 9.9 18.5 36.5 30.7 37.3 24.5 9.5 17.0 92.1 53.0 63.5 20.6 38.8 36.0 95.7 61.8 52.0 178.6 58.9 29.3 28.5 11.8 26.9 36.3 48.7 1.8 2.2 3.3 2.9 1.8 12.8 1.4 3.2 4.1 2.0 1.9 2.7 3.1 6.0 3.6 1.6 1.3 6.0 1.4 48.3 58.7 45.9 53.3 39.5 56.1 61.1 51.3 60.0 59.7 49.1 64.2 34.3 28.9 30.7 78.0 32.4 51.4 15.0 10.2 33.6 8.2 22.8 18.2 172.6 10.0 18.7 18.4 14.6 15.0 32.9 25.8 11.7 10.6 2.8 21.6 20.9 29.3 19.8 32.6 17.0 19.6 15.9 30.0 18.8 19.6 8.8 11.8 40.4 23.5 17.5 3.3 34.6 19.5 8.2 49.5 51.6 3.3 29.2 35.5 30.2 124.6 29.0 11.4 15.5 131.2 153.5 50.1 19.3 38.4 28.5 30.6 25.1 16.6 27.9 24.2 19.7 28.1 35.9 7.7 6.0 29.2 49.2 64.3 41.6 28.7 15.6 33.1 NEK8 NPHP9 ENSG00000160602 "NIMA related kinase 8" Q86SG6 17 28725897-28743455 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 14.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA040661, HPA040679" Approved Approved "Nuclear speckles,Microtubules,Mitotic spindle" Yes NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 7: Kidney - Transmembrane transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Microtubules "Nuclear speckles, Mitotic spindle" "HPA040661: AB_10794065, HPA040679: AB_10796226" "unprognostic (2.63e-1)" "unprognostic (4.57e-2)" "prognostic unfavorable (6.98e-4)" "unprognostic (6.25e-2)" "unprognostic (2.23e-2)" "unprognostic (5.93e-3)" "unprognostic (6.48e-2)" "prognostic favorable (4.52e-4)" "unprognostic (7.85e-2)" "unprognostic (1.37e-1)" "unprognostic (1.51e-3)" "unprognostic (1.55e-1)" "unprognostic (4.87e-3)" "unprognostic (4.61e-2)" "unprognostic (3.58e-1)" "unprognostic (1.75e-1)" "unprognostic (4.67e-3)" 1.5 3.1 1.7 3.3 1.9 1.7 2.4 1.4 1.9 2.5 3.8 2.4 3.0 1.5 3.2 2.5 3.9 2.0 1.0 1.4 1.6 9.1 5.2 3.3 5.8 2.0 1.7 1.9 4.5 2.9 4.4 2.6 1.7 4.0 2.2 0.6 3.7 2.6 0.5 3.1 4.2 1.2 1.6 5.8 3.4 3.8 1.9 2.7 7.2 0.4 5.0 2.6 2.2 2.3 2.1 3.4 3.5 2.8 1.9 2.1 10.9 0.9 2.1 1.3 1.7 5.4 5.0 13.1 3.5 2.8 2.5 3.8 5.2 4.8 1.3 3.5 6.4 2.9 5.8 10.1 3.3 1.8 3.7 4.8 1.8 2.5 5.8 1.8 0.9 1.9 4.3 1.3 1.5 4.7 1.9 3.4 3.3 3.7 1.0 4.9 2.3 5.9 7.0 5.7 6.4 1.5 3.0 6.3 1.6 4.7 9.3 2.4 0.8 1.3 2.2 1.6 1.0 1.5 1.8 8.9 2.0 1.6 3.1 3.3 0.9 1.2 0.7 0.5 0.8 2.8 0.6 0.7 0.1 4.2 0.7 1.0 0.4 1.3 1.1 14.8 0.5 0.8 1.7 1.9 1.4 1.9 1.4 1.6 2.0 1.7 1.7 1.6 1.9 2.3 2.7 9.6 19.3 3.9 22.9 2.8 9.2 8.3 7.4 2.8 10.1 14.1 1.7 12.8 11.6 25.8 8.4 17.6 19.1 14.9 7.9 5.8 9.5 12.8 6.0 2.9 10.3 7.0 0.7 6.0 9.2 3.9 6.1 15.2 26.6 3.2 3.3 9.4 3.9 1.7 0.5 14.4 10.2 5.0 2.7 2.0 3.4 4.4 3.6 2.8 4.0 2.6 3.1 1.5 1.6 3.9 17.2 2.6 7.2 8.6 13.4 4.3 14.3 1.8 0.0 11.7 3.0 19.9 11.4 8.8 1.6 11.1 4.9 7.8 15.9 4.2 NEPRO "C3orf17, DKFZP434F2021, NET17" ENSG00000163608 "Nucleolus and neural progenitor protein" Q6NW34 3 113002444-113019861 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Theca cells: 33.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069654 Supported Nucleoplasm,Nucleoli Yes No "Cluster 15: NK-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nucleoli" "HPA069654: AB_2686164" "unprognostic (8.45e-3)" "unprognostic (3.84e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.13e-4)" "unprognostic (2.29e-2)" "unprognostic (2.43e-2)" "prognostic unfavorable (4.25e-4)" "unprognostic (2.04e-1)" "unprognostic (1.49e-2)" "unprognostic (4.98e-2)" "unprognostic (1.72e-2)" "unprognostic (9.29e-3)" "unprognostic (5.40e-2)" "unprognostic (1.69e-1)" "unprognostic (2.78e-1)" "unprognostic (1.69e-1)" "unprognostic (3.28e-2)" 6.7 6.7 4.7 7.0 5.4 10.6 8.8 6.9 6.5 6.5 6.3 7.0 7.1 8.4 10.3 6.0 6.5 7.4 8.4 5.2 4.9 6.3 5.9 6.4 12.3 5.8 5.3 8.1 8.2 6.9 6.6 6.7 5.6 6.6 5.4 11.7 6.9 6.1 18.7 10.8 7.0 5.8 5.1 8.8 8.3 11.3 5.3 9.4 11.5 7.7 7.8 6.7 5.3 7.9 13.6 10.9 17.3 13.0 5.5 10.1 9.2 12.6 8.1 6.9 4.7 10.1 8.5 17.6 6.6 4.3 9.6 13.7 12.7 5.8 9.4 3.5 8.0 27.3 10.0 7.5 10.0 17.4 9.4 15.7 10.0 5.5 14.2 18.8 6.1 17.2 9.5 13.5 5.2 8.6 15.1 10.3 18.1 12.0 14.0 12.1 13.7 9.3 7.8 11.2 11.9 17.3 7.3 9.1 21.4 12.7 10.4 14.7 12.4 9.4 9.3 3.6 9.1 13.3 11.2 20.6 15.2 13.6 7.0 1.9 1.3 1.6 2.2 1.6 2.3 1.8 2.6 1.9 1.8 1.4 3.2 3.2 0.8 4.3 0.7 1.3 1.2 1.4 4.7 5.4 6.9 6.5 5.2 4.9 5.8 5.3 5.6 5.1 5.3 7.9 16.3 9.6 12.8 0.0 7.6 0.0 0.0 0.0 0.0 0.0 17.4 16.9 0.0 0.0 10.5 18.4 0.0 18.4 23.4 0.0 17.6 14.1 0.0 11.9 20.7 6.3 0.0 0.0 0.0 12.6 15.5 9.3 0.0 16.1 17.7 24.0 0.0 0.0 15.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 9.3 0.0 0.0 0.0 0.0 14.4 0.0 0.0 4.5 0.0 0.0 14.8 8.7 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 20.4 9.1 33.9 0.0 0.0 NET1 "ARHGEF8, NET1A" ENSG00000173848 "Neuroepithelial cell transforming 1" Q7Z628 10 5412557-5459056 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 242.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 8.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 252.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020068 Uncertain Approved Nucleoplasm,Vesicles Yes Yes "Cluster 32: T-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA020068: AB_2670348" "unprognostic (1.77e-2)" "unprognostic (1.87e-1)" "unprognostic (3.40e-1)" "unprognostic (4.05e-2)" "unprognostic (3.37e-3)" "unprognostic (2.15e-1)" "prognostic unfavorable (3.87e-5)" "unprognostic (6.31e-2)" "unprognostic (1.87e-1)" "unprognostic (2.77e-2)" "prognostic unfavorable (8.27e-4)" "unprognostic (2.26e-1)" "unprognostic (5.41e-2)" "unprognostic (1.20e-1)" "unprognostic (1.90e-1)" "unprognostic (3.01e-1)" "unprognostic (2.46e-1)" 48.8 10.8 35.5 23.4 34.2 40.5 52.8 38.5 57.6 43.7 52.8 92.2 56.2 41.8 56.2 68.4 46.2 35.9 13.2 30.2 32.4 49.3 45.1 22.2 26.7 41.8 37.2 28.5 37.9 5.4 10.6 65.7 43.8 41.3 88.2 6.5 93.1 24.3 25.0 39.8 74.7 36.9 37.5 8.1 77.8 14.4 41.1 30.4 26.2 28.0 33.0 60.8 59.3 40.1 115.9 67.7 45.2 51.0 26.8 11.9 252.9 69.1 37.6 53.4 50.4 36.4 215.2 40.6 27.7 42.4 11.4 185.5 54.9 104.3 63.9 38.1 38.5 77.5 22.9 84.0 7.2 21.5 31.1 18.2 61.0 54.0 12.3 47.6 31.1 42.6 138.5 64.4 30.0 54.3 74.3 30.6 61.5 158.6 51.0 45.0 85.0 32.4 33.4 57.6 38.5 20.6 60.7 110.9 20.3 76.2 36.7 65.3 29.5 20.3 30.9 30.7 56.0 39.3 23.1 53.4 18.1 33.1 43.4 2.0 0.6 1.4 0.6 1.0 0.0 1.4 1.2 0.4 4.9 0.6 8.7 1.7 0.1 0.8 0.4 2.0 4.0 2.2 35.5 34.2 38.5 57.6 30.2 32.4 41.8 37.2 43.8 37.5 41.1 40.1 18.4 32.1 55.8 2.6 12.7 40.3 127.2 49.0 103.0 11.0 52.6 28.3 12.1 41.5 84.3 12.9 4.2 110.2 8.4 242.2 5.9 13.1 2.4 97.7 30.6 42.7 80.8 54.1 5.1 24.4 109.1 33.2 107.0 131.4 15.2 16.9 12.5 55.7 14.5 3.3 7.7 145.3 34.6 10.5 59.8 2.4 21.8 31.2 35.6 44.0 48.7 3.8 0.0 8.5 5.7 62.1 148.3 87.6 39.2 67.8 123.6 29.2 85.7 3.5 111.7 183.0 185.0 26.3 16.0 158.1 32.4 117.5 9.3 2.9 145.0 186.5 NEXMIF "KIAA2022, KIDLIA, MRX98, XPN" ENSG00000050030 "Neurite extension and migration factor" Q5QGS0 X 74732856-74925472 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 3.6;Breast glandular cells: 1.4;Club cells: 2.5;Hofbauer cells: 1.3;Respiratory ciliated cells: 2.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "HAP1: 3.7;Karpas-707: 5.9;SiHa: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000407 Uncertain Supported "Nucleoplasm,Midbody,Mitotic spindle,Cytosol" Yes NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Midbody, Mitotic spindle, Cytosol" "HPA000407: AB_2665984" "unprognostic (1.04e-3)" "unprognostic (6.07e-5)" "unprognostic (1.81e-2)" "unprognostic (2.07e-5)" "unprognostic (2.15e-1)" "unprognostic (2.18e-2)" "unprognostic (3.37e-1)" "unprognostic (1.74e-3)" "unprognostic (3.71e-1)" "unprognostic (1.79e-2)" "unprognostic (1.64e-3)" "unprognostic (8.25e-2)" "unprognostic (7.58e-3)" "unprognostic (1.37e-2)" "unprognostic (3.80e-2)" "unprognostic (2.79e-4)" "unprognostic (6.94e-4)" 0.1 0.9 3.0 0.1 3.1 0.0 0.3 1.0 2.5 0.4 0.0 0.8 0.1 0.5 0.2 0.3 0.3 0.1 0.0 2.6 6.7 0.7 0.0 0.1 0.1 0.3 0.7 0.4 1.5 1.8 1.7 0.1 0.5 0.9 0.3 1.0 0.4 0.6 0.0 0.3 0.4 0.7 0.2 0.1 0.6 0.2 4.8 0.0 0.4 0.1 0.1 0.2 0.2 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 5.9 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 5.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 3.1 1.0 2.5 2.6 6.7 0.3 0.7 0.5 0.2 4.8 0.7 0.3 0.0 3.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.4 0.6 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.9 0.1 0.4 0.0 0.5 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 2.9 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 NFAT5 "KIAA0827, NF-AT5, NFATL1, NFATZ, OREBP, TONEBP" ENSG00000102908 "Nuclear factor of activated T cells 5" O94916 16 69565094-69704666 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 281.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SiHa: 22.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057304, HPA069711" Approved Supported Nucleoplasm,Cytosol Yes No "Cluster 10: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA057304: AB_2683407, HPA069711: AB_2686180" "unprognostic (2.71e-1)" "unprognostic (1.50e-2)" "unprognostic (1.77e-1)" "unprognostic (3.57e-2)" "unprognostic (5.65e-3)" "unprognostic (2.08e-1)" "unprognostic (2.97e-2)" "unprognostic (1.26e-1)" "unprognostic (1.83e-1)" "unprognostic (3.56e-2)" "unprognostic (4.05e-3)" "unprognostic (1.87e-1)" "prognostic favorable (1.08e-4)" "unprognostic (1.62e-1)" "unprognostic (1.37e-1)" "unprognostic (6.32e-2)" "unprognostic (9.42e-2)" 2.3 3.1 0.6 2.8 1.2 5.6 2.1 0.5 3.7 3.7 0.0 2.0 0.7 3.3 0.7 2.9 1.9 1.5 2.0 1.4 2.2 2.6 2.3 3.1 1.1 0.0 0.6 2.5 1.6 4.0 2.0 4.2 0.0 2.3 1.5 4.2 3.7 2.4 2.7 3.5 1.9 1.8 0.0 2.5 2.3 1.4 3.0 2.2 3.6 4.8 1.4 2.7 3.1 0.0 8.4 10.1 4.8 5.0 5.8 6.0 6.4 7.2 8.6 6.6 4.2 4.5 4.2 4.5 5.8 5.8 3.4 7.3 3.9 3.1 4.2 2.9 3.2 2.6 2.8 6.2 3.4 3.5 5.5 3.5 1.1 6.4 5.9 5.4 5.5 2.3 7.2 1.1 3.3 3.2 2.8 1.7 2.5 1.1 2.5 4.5 2.2 1.7 2.5 8.0 3.1 0.9 22.2 1.3 2.6 4.1 3.3 1.3 13.1 5.7 5.6 4.8 2.2 4.6 4.9 7.3 5.1 3.4 3.6 0.4 0.1 0.2 0.2 0.1 0.2 0.2 0.1 0.3 0.1 0.2 0.1 0.0 0.9 0.0 0.2 0.5 0.1 0.0 0.6 1.2 0.5 3.7 1.4 2.2 0.0 0.6 0.0 0.0 3.0 0.0 65.0 48.1 49.7 236.7 55.7 148.1 94.8 42.5 155.4 51.8 61.6 42.9 9.2 30.0 43.3 145.3 85.5 60.6 69.4 27.8 5.9 17.8 7.2 93.7 87.8 93.6 24.5 27.3 281.8 12.7 15.9 60.9 38.2 158.3 19.7 31.0 52.8 28.3 17.6 60.6 189.3 29.1 28.5 21.7 169.5 6.9 59.4 58.2 58.7 172.4 37.4 45.7 36.0 177.4 167.2 23.7 29.3 54.9 50.2 83.1 24.7 14.6 31.8 62.4 26.3 72.0 51.4 84.5 48.8 77.9 140.1 50.9 57.4 43.1 20.8 105.7 NFRKB "DKFZp547B2013, INO80G" ENSG00000170322 "Nuclear factor related to kappaB binding protein" Q6P4R8 11 129863636-129895590 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007082, HPA007128" Approved Enhanced Nucleoplasm Yes No "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 36: HEL - Hemostasis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "HPA007082: AB_1079481, HPA007128: AB_1079482" "unprognostic (1.22e-1)" "unprognostic (3.42e-2)" "unprognostic (2.12e-1)" "unprognostic (9.41e-2)" "unprognostic (6.56e-2)" "unprognostic (2.65e-2)" "prognostic unfavorable (5.78e-4)" "unprognostic (6.36e-3)" "unprognostic (1.68e-2)" "unprognostic (1.82e-1)" "unprognostic (2.00e-1)" "unprognostic (5.31e-2)" "unprognostic (9.22e-2)" "unprognostic (4.15e-2)" "unprognostic (6.57e-2)" "unprognostic (7.14e-2)" "unprognostic (3.93e-2)" 9.8 9.0 7.2 10.8 9.9 22.7 11.0 9.7 7.3 15.0 9.1 11.8 13.1 15.6 17.5 13.2 17.9 9.9 7.5 8.3 6.5 10.6 11.8 10.8 14.5 4.9 5.5 20.6 13.9 10.5 11.7 13.1 5.5 12.4 10.1 9.8 14.3 13.3 15.4 21.9 12.4 13.5 4.5 11.2 11.2 20.3 7.2 15.0 20.0 9.7 13.4 12.6 13.8 6.7 17.9 16.8 37.4 20.3 15.6 15.4 23.5 12.2 11.0 14.2 13.9 52.6 30.1 42.6 32.5 9.4 20.8 44.8 36.5 23.8 13.2 16.9 31.9 84.2 32.8 22.2 11.4 21.7 27.3 9.9 25.9 23.3 24.3 16.3 24.9 28.1 49.9 31.5 14.4 16.2 18.6 37.1 19.1 26.2 39.1 27.2 16.3 19.6 17.7 55.6 19.0 20.0 27.4 26.7 7.3 27.5 62.3 19.9 19.7 21.1 20.6 15.6 15.4 10.0 13.3 39.0 8.8 41.9 18.5 6.6 5.1 6.3 6.0 5.8 6.3 3.3 6.1 5.1 5.1 3.9 5.0 4.2 6.0 2.4 5.2 4.5 4.4 4.5 7.2 9.9 9.7 7.3 8.3 6.5 4.9 5.5 5.5 4.5 7.2 6.7 6.2 9.6 15.0 17.0 10.0 29.3 16.8 17.5 18.8 10.2 12.1 10.0 7.6 20.0 17.0 7.3 10.4 19.2 7.8 9.5 7.9 11.9 14.8 12.9 14.4 9.5 8.5 9.4 13.1 10.0 15.6 9.7 6.1 17.8 10.8 14.1 8.9 10.9 10.4 8.4 10.7 9.7 8.2 7.7 6.2 7.1 14.6 8.4 14.2 9.4 12.4 9.7 12.3 12.1 7.7 10.9 8.0 10.5 10.5 15.4 15.6 8.1 12.9 11.1 32.9 10.8 14.2 43.0 49.0 10.7 35.2 23.3 13.1 9.4 12.2 17.9 NGDN "C14orf120, CANu1, DKFZP564O092, LCP5, lpd-2, NGD" ENSG00000129460 Neuroguidin Q8NEJ9 14 23469689-23509862 "Predicted intracellular proteins" "Translation regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000944 Approved Approved Nucleoplasm,Nucleoli,Mitochondria Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Mitochondria" Nucleoplasm "HPA000944: AB_1079483" "unprognostic (2.63e-3)" "unprognostic (7.65e-2)" "unprognostic (2.84e-1)" "unprognostic (4.16e-3)" "unprognostic (1.51e-2)" "unprognostic (3.14e-2)" "unprognostic (8.87e-2)" "unprognostic (1.72e-3)" "unprognostic (5.64e-2)" "unprognostic (3.87e-3)" "unprognostic (7.10e-2)" "unprognostic (1.65e-1)" "unprognostic (6.36e-2)" "unprognostic (9.83e-2)" "unprognostic (2.29e-2)" "unprognostic (2.58e-1)" "unprognostic (1.70e-1)" 32.2 26.4 25.6 23.3 28.4 64.4 40.3 30.5 37.7 30.5 25.0 30.1 23.4 34.7 32.5 26.2 32.0 17.6 23.7 25.9 26.6 31.3 32.9 24.2 35.3 27.1 27.0 39.6 25.7 33.3 20.8 29.2 27.7 24.8 29.0 25.2 24.6 26.6 53.4 35.2 26.8 31.4 27.7 28.6 27.0 28.6 26.9 37.5 28.4 39.2 36.8 32.3 27.7 31.7 37.6 73.1 54.5 51.5 52.0 37.3 72.1 48.6 50.7 101.3 81.4 72.1 66.8 92.6 35.0 44.7 71.1 63.7 109.0 60.1 118.7 61.8 57.3 83.2 44.1 229.3 70.5 110.4 56.9 46.5 75.0 79.9 94.4 39.6 52.2 69.5 93.6 64.1 50.4 88.8 82.3 86.0 69.5 84.8 97.1 67.1 65.6 47.9 65.7 70.4 55.6 62.8 57.6 68.3 83.8 55.0 42.2 70.4 39.8 47.8 57.3 45.1 71.3 79.4 148.7 133.3 20.6 56.1 52.2 67.0 62.3 58.5 88.0 71.8 93.5 129.0 94.6 89.9 74.8 107.7 121.3 95.5 19.1 109.5 71.7 79.1 116.1 93.3 25.6 28.4 30.5 37.7 25.9 26.6 27.1 27.0 27.7 27.7 26.9 31.7 33.8 35.3 29.2 2.9 52.1 70.6 63.8 78.2 72.8 23.2 25.5 31.2 20.2 21.5 46.8 27.6 16.7 59.3 45.3 19.9 33.2 38.6 7.2 24.3 25.9 36.5 24.6 35.1 7.5 36.0 43.3 34.4 16.3 27.5 45.0 23.2 25.4 21.4 29.8 25.2 6.8 22.7 28.5 19.2 39.0 6.9 35.1 21.1 32.0 9.4 34.3 26.8 46.4 4.0 11.0 31.1 22.8 28.2 30.4 42.9 25.8 35.5 36.6 28.6 19.7 51.5 36.0 68.7 64.2 39.6 67.6 57.2 47.6 20.5 27.2 49.5 NGRN DSC92 ENSG00000182768 "Neugrin, neurite outgrowth associated" Q9NPE2 15 90265659-90275778 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 385.3;skeletal muscle: 376.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 75.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041367, HPA076267" Approved Supported "Nucleoplasm,Cytokinetic bridge,Mitochondria" "Intracellular and membrane" Yes No "Cluster 35: T-regs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 59: Non-specific - Transcription" Mitochondria "Nucleoplasm, Cytokinetic bridge" "HPA041367: AB_10796668, HPA076267: " "unprognostic (2.82e-1)" "unprognostic (1.04e-2)" "unprognostic (1.66e-3)" "unprognostic (2.34e-1)" "unprognostic (2.21e-1)" "unprognostic (3.19e-2)" "unprognostic (2.94e-2)" "unprognostic (5.00e-2)" "unprognostic (7.78e-2)" "unprognostic (1.93e-2)" "unprognostic (5.22e-2)" "unprognostic (7.22e-2)" "unprognostic (3.31e-2)" "unprognostic (2.10e-1)" "unprognostic (2.05e-1)" "unprognostic (1.68e-3)" "unprognostic (3.21e-1)" 61.0 91.8 322.8 32.9 334.0 31.7 61.4 312.4 385.3 68.8 312.1 47.0 39.7 63.4 98.3 51.7 65.3 47.1 133.0 332.8 329.8 71.7 59.1 50.3 31.8 316.3 322.1 67.8 46.4 87.6 3.0 46.4 318.1 80.1 51.1 157.0 46.3 88.9 376.8 32.6 35.6 74.6 324.8 37.0 41.5 54.2 334.5 39.6 74.0 291.8 37.4 69.2 2.7 320.9 62.1 127.8 151.7 99.7 138.4 63.9 70.4 100.7 88.4 110.5 94.0 133.2 90.5 38.4 113.8 108.9 110.2 118.2 120.3 64.7 121.5 42.6 104.6 61.0 88.4 110.6 117.7 44.5 36.1 83.4 183.3 60.8 132.9 83.7 79.5 45.7 105.0 64.7 112.8 106.5 35.9 53.5 152.7 198.8 55.0 65.6 72.8 63.1 109.8 168.3 145.8 117.0 107.1 90.1 239.1 149.1 141.9 82.6 64.6 138.3 92.3 85.7 161.7 96.9 268.2 66.4 76.8 90.1 106.4 66.4 62.1 99.0 87.2 65.2 109.9 107.7 106.1 101.9 59.2 105.7 122.6 106.8 23.4 86.7 76.0 62.8 133.5 108.0 322.8 334.0 312.4 385.3 332.8 329.8 316.3 322.1 318.1 324.8 334.5 320.9 10.8 19.2 27.4 21.5 26.2 7.1 10.6 3.7 75.1 10.4 9.1 5.8 10.1 1.5 21.6 5.5 10.4 5.9 5.0 12.1 5.9 33.6 1.9 16.2 14.6 15.8 26.5 12.0 58.3 23.4 4.5 23.0 30.1 9.4 20.3 5.5 7.5 3.8 4.2 16.8 54.0 14.4 4.1 3.8 3.6 4.0 9.0 8.4 8.8 16.9 11.6 15.1 0.0 12.5 22.2 29.9 20.0 8.6 25.0 9.2 12.6 7.8 59.8 11.2 13.1 10.5 19.6 5.2 4.3 55.2 5.1 6.7 19.9 5.7 15.4 8.7 NHLH2 "bHLHa34, HEN2, NSCL2" ENSG00000177551 "Nescient helix-loop-helix 2" Q02577 1 115836377-115843917 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 7.4;esophagus: 2.3;retina: 2.1;skin 1: 3.3" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 14.8;Oligodendrocyte precursor cells: 4.5;Oligodendrocytes: 7.9;Spermatocytes: 5.1;Squamous epithelial cells: 7.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "SCLC-21H: 58.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA055238 Uncertain Approved "Nucleoplasm,Nuclear bodies" Yes NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 37: Myocytes - Muscle contraction" "Nuclear bodies" Nucleoplasm "HPA055238: AB_2682752" "unprognostic (2.20e-2)" "unprognostic (2.28e-1)" "unprognostic (1.97e-1)" "unprognostic (1.82e-1)" "unprognostic (2.17e-1)" "unprognostic (1.58e-1)" "unprognostic (4.82e-2)" "unprognostic (1.11e-2)" "unprognostic (5.26e-2)" "unprognostic (9.55e-2)" "unprognostic (2.80e-3)" "unprognostic (1.53e-1)" "unprognostic (3.09e-1)" "unprognostic (2.25e-1)" 0.0 0.0 2.0 0.0 1.4 0.0 0.1 5.9 2.1 0.3 0.2 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.0 3.2 4.0 0.0 0.0 0.2 0.0 3.8 5.1 0.0 0.0 0.0 0.2 0.0 7.4 0.2 0.0 2.1 0.4 0.1 0.2 3.3 0.0 0.0 2.5 0.0 0.2 0.4 6.7 0.0 0.0 0.0 0.0 0.0 0.7 3.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 58.4 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.4 5.9 2.1 3.2 4.0 3.8 5.1 7.4 2.5 6.7 3.0 0.0 0.0 0.0 0.3 0.0 2.8 2.8 3.3 14.8 3.9 0.0 0.6 3.4 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.2 1.8 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.3 0.0 4.5 7.9 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.4 0.0 3.5 0.3 5.1 3.4 7.0 2.3 0.0 0.0 0.0 0.0 0.4 NIFK "hNIFK, MKI67IP, Nopp34" ENSG00000155438 "Nucleolar protein interacting with the FHA domain of MKI67" Q9BYG3 2 121726945-121736911 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015382, HPA035735, HPA035736, CAB075728, CAB075729" Supported Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim" "Mitotic chromosome" "CAB015382: AB_2142390, CAB075728: AB_2665734, CAB075729: AB_2665735, HPA035735: AB_2674758, HPA035736: AB_2674759" "unprognostic (3.53e-2)" "unprognostic (1.67e-1)" "unprognostic (3.49e-1)" "prognostic unfavorable (5.57e-4)" "unprognostic (1.21e-1)" "unprognostic (4.15e-3)" "prognostic unfavorable (2.92e-6)" "unprognostic (7.74e-3)" "unprognostic (4.63e-2)" "unprognostic (3.21e-2)" "unprognostic (6.02e-3)" "unprognostic (9.50e-2)" "prognostic unfavorable (5.01e-11)" "unprognostic (1.72e-1)" "unprognostic (1.29e-1)" "unprognostic (1.27e-1)" "unprognostic (1.28e-1)" 29.3 24.8 18.1 31.9 18.6 31.5 37.3 18.7 21.8 25.4 17.9 24.8 25.1 28.5 21.9 34.6 27.5 25.1 22.9 19.3 18.7 25.7 34.1 17.9 47.2 18.5 17.8 36.5 32.6 17.9 16.7 25.6 18.4 24.6 25.6 23.0 17.9 17.8 38.3 34.5 20.1 24.8 19.1 22.3 22.5 21.8 18.3 32.9 25.2 18.3 42.4 43.3 24.5 20.1 118.4 37.6 68.8 68.3 57.9 80.6 90.2 90.6 75.2 105.0 113.2 105.9 55.0 152.4 111.4 66.9 93.1 72.9 149.4 116.4 153.4 101.3 85.7 155.0 44.5 92.9 82.6 141.1 81.7 80.6 126.7 137.4 184.4 48.7 75.9 60.3 174.5 73.9 90.5 58.2 109.5 140.9 175.3 132.4 122.5 102.5 80.7 191.2 92.1 72.4 88.1 91.8 56.6 105.1 200.7 62.2 52.0 123.1 45.7 72.8 123.5 85.6 129.3 87.5 150.6 182.1 55.7 143.9 101.5 41.8 54.2 28.8 59.2 65.3 83.4 73.6 72.3 68.6 72.1 74.8 84.5 79.4 4.0 81.5 62.5 64.0 68.9 75.1 18.1 18.6 18.7 21.8 19.3 18.7 18.5 17.8 18.4 19.1 18.3 20.1 51.1 44.8 25.9 8.1 56.3 98.4 128.9 87.0 81.4 25.8 51.2 88.8 21.5 24.3 62.2 14.7 12.5 74.9 62.7 18.9 46.9 64.2 23.7 43.8 126.9 47.7 28.1 41.8 8.2 45.2 90.6 68.7 32.6 39.9 54.5 47.9 26.0 33.2 54.4 13.5 7.2 41.3 42.7 34.5 32.8 8.0 57.5 39.0 23.2 10.3 59.1 48.0 54.6 13.0 8.0 51.5 28.4 45.1 33.3 107.0 18.4 58.4 41.9 45.8 39.5 72.7 54.3 81.1 83.9 79.3 101.4 48.8 52.5 97.7 60.5 125.2 NINL "KIAA0980, NLP" ENSG00000101004 "Ninein like" Q9Y2I6 20 25452697-25585531 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 42.4;Granulosa cells: 29.6;Inhibitory neurons: 32.6;Oligodendrocyte precursor cells: 47.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 37.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA000686 Uncertain Uncertain "Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" "Microtubules, Cytokinetic bridge, Cytosol" "HPA000686: AB_1079193" "unprognostic (7.33e-2)" "unprognostic (1.14e-1)" "unprognostic (1.13e-1)" "unprognostic (2.63e-2)" "unprognostic (4.84e-2)" "unprognostic (4.64e-2)" "unprognostic (1.16e-1)" "unprognostic (8.56e-2)" "unprognostic (2.50e-1)" "unprognostic (7.56e-2)" "prognostic favorable (1.47e-4)" "unprognostic (3.39e-1)" "prognostic favorable (1.03e-5)" "unprognostic (3.95e-2)" "unprognostic (2.72e-1)" "unprognostic (1.51e-1)" "unprognostic (6.26e-2)" 4.0 8.6 4.9 2.0 5.9 0.6 4.0 10.4 6.1 10.1 8.8 9.8 3.2 7.2 7.2 5.8 5.2 3.3 4.0 4.4 6.9 15.1 8.1 4.1 2.2 7.9 7.1 18.9 5.4 8.2 9.9 1.5 7.0 8.8 2.1 4.7 4.4 3.7 4.5 2.4 3.9 3.5 5.5 4.9 6.3 7.7 6.5 15.7 10.2 1.2 2.2 3.6 8.5 6.8 1.0 10.8 23.0 15.1 2.6 7.5 7.1 3.6 3.1 3.1 4.4 2.8 7.5 0.6 5.0 5.6 7.6 0.8 3.4 0.7 2.6 0.5 4.7 1.6 5.0 37.5 5.4 0.6 0.1 9.2 0.7 3.6 0.0 8.8 6.8 17.8 1.9 0.3 3.8 9.6 21.7 0.7 6.5 0.1 1.1 0.5 17.9 0.8 1.5 1.3 22.7 16.0 8.2 3.0 9.1 18.3 4.9 6.4 0.3 0.1 8.6 0.1 0.2 2.3 4.4 0.1 0.2 0.6 3.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 4.9 5.9 10.4 6.1 4.4 6.9 7.9 7.1 7.0 5.5 6.5 6.8 1.2 0.0 14.6 42.4 0.8 2.0 4.9 2.5 5.7 3.0 2.8 3.3 6.5 12.8 4.8 7.3 25.0 2.8 0.6 0.4 0.0 5.6 0.6 4.2 7.3 2.3 6.1 0.0 7.4 1.2 1.3 8.7 4.6 3.4 0.0 29.6 8.9 8.4 2.3 8.4 32.6 2.3 8.2 0.3 2.0 2.7 13.1 0.8 0.0 12.2 0.0 3.2 2.1 47.3 19.4 2.8 1.5 12.4 0.9 4.5 0.7 8.8 13.7 1.9 6.6 10.8 4.7 2.5 5.0 4.3 0.9 1.5 1.1 21.0 2.5 1.9 NISCH "I-1, IRAS, KIAA0975" ENSG00000010322 Nischarin Q9Y2I1 3 52455118-52493068 "FDA approved drug targets, Predicted intracellular proteins" Apoptosis Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Enteroendocrine cells: 169.3;Peritubular cells: 246.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023189 Approved Approved "Nucleoplasm,Vesicles,Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 34: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Nucleoplasm, Cytosol" "Vesicles, Microtubules, Cytokinetic bridge" "HPA023189: AB_1854495" "unprognostic (6.66e-2)" "unprognostic (1.58e-1)" "unprognostic (1.59e-3)" "unprognostic (4.11e-3)" "unprognostic (1.64e-1)" "unprognostic (8.08e-3)" "unprognostic (1.60e-2)" "unprognostic (6.56e-3)" "unprognostic (4.96e-2)" "unprognostic (8.33e-3)" "prognostic favorable (1.91e-4)" "unprognostic (1.40e-2)" "unprognostic (5.10e-2)" "unprognostic (1.19e-1)" "unprognostic (2.94e-2)" "unprognostic (1.47e-1)" "unprognostic (7.05e-3)" 55.2 69.8 46.5 28.7 55.5 38.7 60.5 78.2 56.6 105.8 22.2 68.5 24.3 76.2 34.0 51.3 72.0 29.9 48.5 56.3 38.7 54.6 45.6 56.2 32.5 20.9 32.6 93.0 54.1 32.5 181.8 39.1 32.9 107.5 20.6 19.0 53.6 51.6 36.3 80.7 55.3 33.0 9.1 54.1 52.7 84.5 35.2 30.1 60.8 16.3 23.3 78.1 71.6 35.2 15.6 16.0 48.8 40.1 35.7 39.2 40.0 32.8 21.5 25.7 26.0 24.2 22.8 21.7 9.0 45.6 21.0 20.4 26.1 35.7 15.1 22.3 28.2 39.2 65.2 23.9 32.4 23.2 33.6 61.9 28.2 27.7 23.5 54.0 42.0 42.4 21.1 23.4 24.3 22.2 41.8 51.2 30.1 19.8 27.1 24.5 13.4 25.4 29.2 30.6 20.6 35.9 35.6 9.3 23.1 42.3 28.9 38.5 46.3 36.0 34.1 36.9 24.1 38.7 23.8 27.3 24.7 37.3 22.4 5.2 4.5 3.5 3.0 4.0 3.1 2.5 2.6 4.0 2.3 2.8 3.1 3.3 1.5 3.2 0.6 3.4 3.0 3.6 46.5 55.5 78.2 56.6 56.3 38.7 20.9 32.6 32.9 9.1 35.2 35.2 26.1 25.6 32.3 34.0 14.9 27.5 14.6 23.3 40.5 40.9 29.2 37.1 20.4 8.6 19.1 14.7 8.4 32.4 24.2 20.5 9.8 12.1 10.3 14.5 26.7 22.1 169.3 4.6 64.9 9.4 14.0 23.4 23.4 18.9 25.3 40.2 46.1 15.3 30.5 28.6 44.0 19.1 22.4 50.5 14.5 25.9 88.3 24.3 19.6 15.0 13.0 12.1 17.5 21.1 26.1 10.0 14.2 246.0 12.4 12.6 16.5 15.6 15.2 22.4 26.3 17.2 24.8 31.2 18.0 16.7 22.3 24.2 18.4 47.6 15.7 11.7 NLN "AGTBP, KIAA1226" ENSG00000123213 Neurolysin Q9BYT8 5 65722205-65871725 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 52.8;Excitatory neurons: 58.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.6;intermediate monocyte: 3.4;myeloid DC: 2.2;non-classical monocyte: 2.3" "Group enriched" "Detected in many" 5 "dendritic cells: 2.2;monocytes: 3.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031862 Approved Approved Mitochondria Yes No 64000 "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA031862: AB_10600827" "unprognostic (5.91e-3)" "unprognostic (4.52e-2)" "unprognostic (1.34e-3)" "unprognostic (4.37e-2)" "unprognostic (3.85e-1)" "unprognostic (1.45e-2)" "unprognostic (7.29e-3)" "unprognostic (3.24e-2)" "unprognostic (3.19e-1)" "unprognostic (3.58e-1)" "prognostic unfavorable (7.51e-4)" "unprognostic (1.27e-1)" "prognostic favorable (5.58e-7)" "unprognostic (1.52e-2)" "unprognostic (1.98e-1)" "unprognostic (1.29e-1)" "unprognostic (6.18e-3)" 2.2 1.0 3.8 2.4 3.9 1.5 3.7 2.9 5.3 1.8 1.6 3.6 1.1 2.7 2.4 2.5 1.5 1.2 2.6 3.8 3.6 3.9 9.9 1.7 1.7 3.9 3.4 1.8 2.5 1.5 0.9 2.4 4.0 2.6 3.2 2.5 1.9 1.1 8.9 2.8 2.7 2.7 3.3 1.3 4.0 1.1 3.9 0.9 2.7 6.5 2.0 2.7 1.5 4.8 13.3 12.5 7.2 12.0 9.0 15.3 14.5 13.1 5.5 7.6 8.2 7.2 7.7 18.8 16.1 15.8 15.1 10.3 9.5 20.2 13.1 5.6 6.4 5.2 8.7 18.5 7.7 12.0 3.0 11.7 10.8 10.5 12.4 6.3 21.7 8.3 11.4 3.9 16.5 10.2 8.3 10.8 22.2 6.7 3.6 9.6 15.3 29.9 12.6 5.9 22.3 11.5 10.6 10.7 11.0 19.4 12.9 14.1 12.5 5.0 5.9 7.4 10.0 3.3 7.1 8.2 7.7 23.2 7.7 0.1 2.6 0.1 0.1 3.4 0.1 0.4 0.2 0.1 2.2 0.4 0.3 0.2 0.3 0.5 2.3 0.1 0.0 1.0 3.8 3.9 2.9 5.3 3.8 3.6 3.9 3.4 4.0 3.3 3.9 4.8 5.9 6.4 2.8 19.6 4.0 5.7 9.0 6.2 8.6 2.4 10.1 8.9 14.5 7.2 8.5 12.9 4.2 5.3 0.6 52.8 5.9 17.8 0.3 7.4 12.9 8.3 1.8 9.0 58.9 14.5 14.0 7.1 20.4 20.9 15.2 16.2 4.6 32.4 28.8 5.0 32.2 5.8 6.1 22.9 8.9 0.4 4.4 13.5 1.8 5.6 17.9 13.1 2.1 22.6 44.5 30.2 35.9 2.2 4.9 16.5 32.3 22.4 3.1 4.7 0.0 19.7 8.1 2.1 5.2 15.3 5.3 2.9 2.3 15.8 8.2 6.1 NME2 "NDPKB, NM23-H2" ENSG00000243678 "NME/NM23 nucleoside diphosphate kinase 2" P22392 17 51165435-51171744 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide metabolism, Transcription, Transcription regulation" "Activator, DNA-binding, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 918.0;Gastric mucus-secreting cells: 438.3;Plasma cells: 778.5;Squamous epithelial cells: 1490.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB036213, CAB036214, CAB036215, HPA041113" Approved Supported "Plasma membrane,Midbody ring,Cytosol" Yes NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane, Midbody ring" "CAB036213: , CAB036214: , CAB036215: , HPA041113: AB_2677305" "unprognostic (7.21e-3)" "prognostic unfavorable (4.74e-4)" "unprognostic (4.85e-2)" "unprognostic (1.15e-2)" "unprognostic (8.86e-2)" "unprognostic (1.42e-2)" "prognostic unfavorable (7.09e-4)" "unprognostic (6.62e-3)" "unprognostic (5.68e-2)" "unprognostic (2.31e-1)" "unprognostic (1.38e-1)" "unprognostic (6.41e-2)" "prognostic unfavorable (1.55e-6)" "unprognostic (2.82e-1)" "unprognostic (9.09e-2)" "unprognostic (8.87e-2)" "unprognostic (3.19e-2)" 503.5 428.3 308.0 259.5 319.0 329.4 489.1 328.0 379.9 439.2 431.1 409.2 335.1 383.4 236.1 610.6 350.6 187.0 403.9 313.7 338.6 478.1 428.4 339.6 288.9 326.6 320.7 500.1 632.0 201.8 234.9 204.8 321.3 367.7 330.4 63.3 432.4 247.5 545.7 540.3 307.6 286.2 326.8 336.0 403.5 77.8 333.3 190.0 305.3 353.7 289.1 463.5 464.2 333.4 1638.6 2233.9 466.1 913.7 969.3 1399.2 1449.2 1091.7 954.0 1404.8 1053.5 1789.7 792.3 1314.3 1662.9 913.0 706.6 956.2 947.3 1273.3 1035.7 1604.8 3283.2 1120.3 1345.8 2513.4 1116.1 1736.0 760.5 1324.1 1420.0 901.9 1466.4 914.6 860.9 856.5 1541.7 773.7 956.1 2741.9 931.3 2144.8 831.4 2974.6 3364.2 875.9 1731.8 2157.2 1417.9 1800.2 1160.6 641.9 674.1 1472.7 1583.0 806.1 1201.7 1268.5 1013.5 1462.8 1158.2 1135.2 1774.8 1520.9 2176.6 1558.1 815.1 919.1 819.2 66.8 243.4 14.0 166.7 325.5 235.6 338.9 211.9 183.3 439.5 259.2 153.5 170.0 13.8 251.6 282.5 478.1 211.2 298.2 308.0 319.0 328.0 379.9 313.7 338.6 326.6 320.7 321.3 326.8 333.3 333.4 9.7 28.9 67.2 0.0 146.8 14.5 8.3 10.8 918.0 0.9 41.6 35.9 0.0 22.8 85.7 5.5 0.0 10.0 10.1 7.1 37.2 47.4 0.6 16.4 34.3 60.9 14.6 298.2 0.0 34.5 27.8 99.0 438.3 21.3 42.9 6.8 22.9 37.6 16.4 0.0 0.0 19.3 8.2 34.8 17.4 2.1 25.7 136.7 10.6 0.0 55.5 0.4 2.1 0.0 0.0 40.7 15.6 12.8 778.5 7.6 11.7 33.8 63.6 0.8 6.6 10.2 43.3 0.6 5.6 1490.1 14.9 8.8 87.0 6.8 25.0 11.0 NME4 "NDPKD, nm23-H4, NM23H4" ENSG00000103202 "NME/NM23 nucleoside diphosphate kinase 4" O00746 16 396725-410367 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid transport, Nucleotide metabolism, Transport" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 250.5;Erythroid cells: 311.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB045997, HPA072588" Approved Supported Mitochondria Yes No "Cluster 26: Non-specific - Mitochondria" "Cluster 15: Liver - Metabolism" "Cluster 14: REH - Unknown function" "Cluster 33: Fibroblasts - ECM organization" Mitochondria "CAB045997: AB_11126630, HPA072588: AB_2686538" "unprognostic (3.27e-1)" "prognostic unfavorable (6.53e-4)" "unprognostic (3.70e-2)" "unprognostic (7.16e-3)" "unprognostic (1.32e-1)" "unprognostic (2.00e-1)" "unprognostic (4.40e-2)" "unprognostic (4.46e-3)" "unprognostic (1.98e-1)" "unprognostic (3.12e-1)" "unprognostic (3.74e-2)" "unprognostic (7.79e-3)" "prognostic unfavorable (1.61e-7)" "unprognostic (3.78e-2)" "unprognostic (2.16e-1)" "unprognostic (6.04e-2)" "unprognostic (3.08e-1)" 89.3 136.1 78.3 26.2 75.6 127.7 72.9 73.5 101.5 88.1 77.3 192.9 21.9 79.5 55.7 50.1 89.1 41.2 101.2 76.4 81.7 60.4 175.2 48.3 21.1 88.6 77.9 86.8 43.7 56.7 64.3 30.8 79.8 143.7 23.5 11.1 70.4 81.9 34.7 31.4 59.7 51.9 78.6 43.8 97.7 44.7 80.3 29.3 51.6 27.2 15.8 145.6 64.3 73.6 1.0 305.4 265.6 366.7 104.0 181.0 59.5 143.6 170.4 211.8 180.6 205.4 176.2 3.0 105.8 230.2 76.9 3.9 145.0 153.9 62.0 126.5 218.7 151.9 40.2 279.9 195.7 111.0 53.1 234.7 79.8 130.5 12.8 152.2 137.6 210.7 159.6 25.8 160.4 255.4 98.5 139.2 271.8 76.1 67.8 485.8 59.3 79.0 150.6 1.2 77.7 419.2 36.8 2.7 139.9 97.2 178.3 257.5 174.0 149.7 216.8 101.8 36.8 2.7 2.0 83.1 65.8 19.8 177.2 12.9 13.3 39.8 14.9 11.9 12.7 27.6 14.4 16.3 17.6 29.9 26.0 13.4 4.2 2.5 10.6 58.3 0.9 10.7 78.3 75.6 73.5 101.5 76.4 81.7 88.6 77.9 79.8 78.6 80.3 73.6 52.2 0.0 13.9 18.6 40.6 32.2 56.3 49.0 40.9 15.2 116.6 135.8 44.5 52.9 25.1 58.8 2.1 71.7 45.7 19.3 250.5 116.5 5.0 30.8 113.3 55.3 45.1 311.8 16.8 40.3 26.1 87.3 29.6 59.8 29.9 199.9 55.6 132.2 131.2 8.4 21.1 38.6 26.4 46.5 68.6 21.6 89.2 35.4 62.2 10.3 46.5 45.9 19.6 10.1 3.6 58.3 23.8 94.8 34.5 121.8 9.0 75.5 7.9 5.6 52.6 40.1 105.8 1.7 32.7 38.6 24.6 21.8 26.2 89.4 54.9 60.9 NME5 "nm23-H5, RSPH23" ENSG00000112981 "NME/NM23 family member 5" P56597 5 138115175-138139443 "Metabolic proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 37.2;testis: 53.3" "Group enriched" "Detected in many" 4 "Early spermatids: 704.9;Endometrial ciliated cells: 205.8;Late spermatids: 256.5;Respiratory ciliated cells: 431.9;Spermatocytes: 326.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "RPTEC TERT1: 29.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035648, HPA044555, HPA058103" Enhanced Approved "Nucleoplasm,Nuclear bodies" Yes NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Nuclear bodies" "HPA035648: AB_2674719, HPA044555: AB_10960286, HPA058103: " "unprognostic (2.49e-2)" "unprognostic (7.63e-4)" "unprognostic (9.97e-2)" "prognostic favorable (7.24e-5)" "unprognostic (3.27e-2)" "unprognostic (2.27e-1)" "unprognostic (3.04e-3)" "unprognostic (3.06e-1)" "unprognostic (1.34e-1)" "unprognostic (2.39e-2)" "unprognostic (1.83e-2)" "unprognostic (2.14e-1)" "prognostic favorable (1.76e-4)" "unprognostic (9.14e-4)" "unprognostic (1.11e-3)" "unprognostic (3.45e-1)" "unprognostic (3.16e-2)" 1.4 6.5 9.7 0.5 10.5 0.0 4.5 9.2 11.7 8.6 18.6 2.1 0.2 4.9 23.1 1.0 37.2 8.7 3.6 10.5 9.2 20.5 0.5 4.5 0.4 10.5 12.3 5.3 4.4 24.3 8.9 0.1 12.1 5.0 1.1 12.9 3.7 4.5 0.4 0.3 0.6 3.1 9.6 0.2 2.8 53.3 11.0 0.7 12.4 0.6 0.2 2.1 0.6 8.9 0.0 0.0 3.9 4.3 0.0 0.0 0.0 0.7 0.4 0.7 0.3 0.1 1.8 0.0 1.1 0.1 0.7 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 1.7 0.0 0.0 2.1 0.0 0.9 0.0 3.8 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.0 1.4 0.0 0.0 0.0 29.9 0.0 6.7 2.5 0.0 0.8 4.9 1.7 0.5 1.6 0.0 0.7 0.0 0.0 0.9 0.4 0.8 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 10.5 9.2 11.7 10.5 9.2 10.5 12.3 12.1 9.6 11.0 8.9 1.0 6.4 7.5 26.8 0.3 0.6 8.5 41.1 0.0 11.7 9.0 7.9 4.3 8.6 38.1 33.1 14.6 0.5 0.1 0.3 86.1 23.8 704.9 205.8 9.2 3.5 5.4 0.0 57.9 4.0 0.0 4.2 2.6 12.7 0.0 7.7 3.6 0.6 0.1 6.7 42.2 3.3 44.7 0.0 0.3 256.5 9.0 1.4 10.6 3.7 0.6 19.1 0.0 11.1 8.1 4.2 0.3 13.9 0.0 4.8 0.2 92.3 431.9 25.8 0.0 0.5 12.6 326.8 24.7 0.0 0.3 0.0 0.8 10.9 1.7 5.9 NOC2L "DKFZP564C186, NET15, NET7, NIR, PPP1R112" ENSG00000188976 "NOC2 like nucleolar associated transcriptional repressor" Q9Y3T9 1 944203-959309 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044258, HPA062195" Approved Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 310000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim, Mitotic chromosome" "HPA044258: AB_10961284, HPA062195: AB_2684707" "unprognostic (3.18e-2)" "unprognostic (5.84e-2)" "unprognostic (1.59e-1)" "unprognostic (9.54e-3)" "unprognostic (6.75e-2)" "unprognostic (2.31e-3)" "unprognostic (1.94e-3)" "unprognostic (1.36e-2)" "unprognostic (1.51e-1)" "unprognostic (2.17e-1)" "unprognostic (1.51e-1)" "unprognostic (2.78e-1)" "unprognostic (1.20e-3)" "unprognostic (8.62e-2)" "unprognostic (6.25e-2)" "unprognostic (3.44e-2)" "unprognostic (1.52e-1)" 26.7 23.6 17.1 23.0 17.1 30.1 26.4 16.8 21.2 29.5 14.3 28.0 17.9 30.3 10.3 47.3 27.7 14.1 32.8 18.1 18.5 27.1 33.7 23.6 23.1 18.5 17.0 26.0 35.6 21.2 24.4 15.8 19.5 26.8 11.6 9.6 26.5 16.0 73.0 45.0 25.2 15.0 15.1 28.0 28.4 36.0 17.6 20.1 24.3 26.4 15.9 32.7 31.7 18.5 112.8 110.4 19.8 129.5 34.5 31.0 70.2 82.3 38.9 114.4 62.1 148.5 110.5 126.3 113.3 56.0 94.0 102.2 147.6 122.8 49.2 79.2 161.5 67.0 141.2 132.0 77.4 151.1 63.8 50.3 35.0 125.3 84.3 35.3 56.4 44.6 190.8 58.2 51.6 182.1 98.7 92.6 112.0 82.3 128.8 120.0 81.5 155.9 53.6 47.4 136.0 133.0 109.3 166.3 105.1 30.3 74.8 81.1 64.1 68.3 95.9 75.2 143.0 97.6 112.5 225.7 84.3 209.1 57.7 21.3 30.9 22.2 23.9 46.4 31.3 23.9 23.3 23.4 36.8 19.3 23.3 18.6 2.8 34.5 57.5 23.6 19.9 31.7 17.1 17.1 16.8 21.2 18.1 18.5 18.5 17.0 19.5 15.1 17.6 18.5 21.5 16.0 23.1 12.4 42.7 69.3 90.8 42.9 47.8 54.6 33.4 34.7 4.5 28.6 29.8 36.8 62.6 63.7 24.7 27.4 17.6 49.9 10.2 34.8 40.9 27.8 30.0 23.8 12.6 46.2 65.5 29.9 28.1 36.9 13.9 36.4 24.7 24.0 39.6 45.4 12.4 27.6 36.7 24.6 29.2 10.3 29.5 24.4 24.9 12.2 35.7 20.6 60.8 9.5 10.6 39.2 21.4 21.4 42.6 71.9 22.9 19.6 27.1 77.0 32.9 41.2 34.6 43.0 83.9 47.4 82.0 58.8 36.6 51.8 53.1 69.3 NOL12 "MGC3731, Nop25, RRP17" ENSG00000273899 "Nucleolar protein 12" Q9UGY1 22 37681673-37693476 "Predicted intracellular proteins" "RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 105.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA003547 Uncertain Approved "Nucleoplasm,Nucleoli,Mitotic chromosome,Vesicles" Yes No "Cluster 34: Basophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoli, Mitotic chromosome" "Nucleoplasm, Vesicles" "HPA003547: AB_10602012" "unprognostic (3.37e-2)" "prognostic favorable (6.80e-5)" "unprognostic (2.65e-1)" "unprognostic (9.62e-2)" "unprognostic (2.13e-1)" "unprognostic (7.89e-2)" "unprognostic (3.23e-3)" "prognostic favorable (9.41e-4)" "unprognostic (9.96e-2)" "unprognostic (4.62e-2)" "unprognostic (2.18e-3)" "unprognostic (4.60e-2)" "prognostic unfavorable (2.56e-6)" "unprognostic (1.34e-2)" "unprognostic (8.40e-2)" "unprognostic (4.65e-2)" "prognostic favorable (3.24e-4)" 17.1 29.2 11.3 15.1 12.7 28.7 17.5 12.1 18.0 20.5 9.6 21.3 14.9 15.5 7.9 35.1 16.2 9.0 18.6 11.8 12.3 22.0 16.2 14.3 20.9 12.3 11.8 18.5 17.5 11.5 16.5 8.1 12.1 19.8 9.5 4.9 20.5 4.4 12.6 22.7 19.5 6.6 11.2 26.5 18.8 10.4 11.8 16.1 23.1 8.2 12.6 17.1 23.3 12.9 38.3 33.5 24.4 29.5 8.1 7.8 32.2 17.1 7.7 7.4 8.4 20.0 15.7 30.2 9.8 6.2 8.1 41.4 11.6 50.0 2.2 34.4 51.9 26.3 28.9 43.6 21.3 59.3 38.2 9.6 12.4 31.2 11.7 10.0 15.3 16.7 19.8 26.9 6.8 32.3 36.4 48.0 29.5 16.6 46.7 48.5 16.7 24.7 18.2 10.1 19.2 40.3 22.1 19.5 30.8 2.7 26.9 31.0 22.9 34.2 32.5 24.8 34.5 24.0 29.9 41.0 33.3 46.2 40.0 57.3 24.4 26.9 15.1 28.4 11.7 14.1 14.8 13.6 17.6 15.8 14.8 12.6 53.1 16.7 33.8 13.6 22.3 11.9 11.3 12.7 12.1 18.0 11.8 12.3 12.3 11.8 12.1 11.2 11.8 12.9 10.9 3.2 15.3 4.9 15.3 39.0 13.7 33.0 25.0 11.0 10.2 7.7 3.5 7.2 20.3 14.7 6.2 19.4 11.0 35.6 3.9 25.7 105.7 5.4 5.0 12.9 12.6 8.8 11.4 29.1 16.2 10.2 15.8 4.7 15.2 9.7 10.8 6.2 13.9 28.6 10.9 24.8 20.3 10.7 21.8 48.3 9.9 12.7 21.4 2.8 17.7 13.8 18.6 5.5 8.2 22.4 39.9 11.3 14.0 8.6 27.4 7.8 15.9 8.3 13.1 10.0 10.6 14.5 25.9 45.4 39.8 19.8 14.3 9.7 24.1 14.5 NOL7 "C6orf90, dJ223E5.2, NOP27, PQBP3, RARG-1" ENSG00000225921 "Nucleolar protein 7" Q9UMY1 6 13615335-13632739 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029185 Supported Supported "Nucleoli,Mitotic chromosome,Mitochondria" Yes Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Mitotic chromosome" Mitochondria "HPA029185: AB_10601274" "unprognostic (8.76e-2)" "unprognostic (8.94e-2)" "unprognostic (8.38e-2)" "unprognostic (1.15e-2)" "unprognostic (3.75e-1)" "unprognostic (5.77e-2)" "unprognostic (2.50e-3)" "unprognostic (1.57e-1)" "unprognostic (4.64e-2)" "prognostic favorable (3.64e-5)" "unprognostic (1.26e-1)" "unprognostic (2.03e-2)" "unprognostic (8.04e-3)" "unprognostic (2.58e-1)" "unprognostic (1.17e-1)" "unprognostic (4.86e-2)" "unprognostic (4.79e-2)" 44.3 43.9 29.5 21.7 30.8 29.5 42.0 32.2 34.0 37.5 28.2 44.8 26.8 37.7 23.4 38.2 35.5 16.6 48.2 28.7 31.1 58.5 37.9 32.2 25.8 30.9 31.4 40.7 48.9 40.2 35.9 21.1 31.0 35.1 19.8 16.6 38.0 19.2 44.5 36.9 36.4 16.0 30.8 37.8 37.9 41.7 30.7 15.2 37.1 17.1 20.3 41.4 34.9 33.8 71.7 37.2 31.7 42.7 26.9 26.1 74.4 71.8 29.3 48.4 44.4 60.0 24.9 97.8 137.4 34.4 57.7 46.5 46.9 42.4 47.8 57.5 105.0 91.2 36.3 104.0 45.4 112.0 61.4 25.5 41.5 42.5 24.2 29.8 33.6 45.5 135.7 22.2 44.7 38.1 70.6 147.6 42.1 37.0 74.1 74.4 46.8 140.5 57.9 21.7 92.5 60.3 40.9 88.0 94.9 36.2 53.6 42.8 65.7 48.0 51.9 57.8 108.3 66.2 123.2 100.2 30.7 70.7 75.6 34.5 59.6 82.1 59.2 76.4 68.2 104.0 84.7 71.4 73.2 87.8 90.7 69.0 27.4 61.9 82.9 91.4 96.0 67.9 29.5 30.8 32.2 34.0 28.7 31.1 30.9 31.4 31.0 30.8 30.7 33.8 103.1 93.0 73.5 10.4 112.5 90.8 117.3 151.0 50.1 62.1 78.9 97.0 214.9 68.6 112.0 57.0 22.9 137.4 71.5 72.7 123.3 188.7 202.3 105.8 95.0 109.2 37.1 89.4 14.0 261.2 153.8 90.9 58.1 91.6 90.6 67.0 61.1 61.8 115.1 48.8 17.1 97.8 130.2 52.6 81.8 38.9 82.6 78.5 101.4 8.4 119.7 124.2 78.2 13.6 19.0 175.0 94.3 79.4 138.8 121.7 81.2 163.6 135.6 61.7 65.7 92.5 119.4 186.3 112.9 70.8 90.5 155.3 99.5 99.2 91.0 117.2 NOL8 "C9orf34, FLJ20736, Nop132" ENSG00000198000 "Nucleolar protein 8" Q76FK4 9 92297358-92325636 "Predicted intracellular proteins" "rRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044440, HPA062922" Uncertain Supported "Nucleoli,Mitotic chromosome" Yes No "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoli "Mitotic chromosome" "HPA044440: AB_10963212, HPA062922: " "unprognostic (3.44e-2)" "unprognostic (1.67e-1)" "unprognostic (9.72e-2)" "unprognostic (1.65e-2)" "unprognostic (1.40e-1)" "unprognostic (9.73e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (1.85e-1)" "unprognostic (6.16e-3)" "unprognostic (5.17e-1)" "unprognostic (1.98e-1)" "unprognostic (1.22e-2)" "prognostic unfavorable (1.02e-5)" "unprognostic (4.69e-2)" "unprognostic (5.38e-2)" "unprognostic (4.58e-1)" "unprognostic (5.53e-2)" 8.6 5.8 4.2 8.0 5.8 6.8 10.0 5.0 5.3 8.2 5.2 8.6 6.0 9.8 7.4 8.7 7.4 6.5 6.8 4.1 5.3 7.2 5.5 6.9 12.0 5.6 5.4 11.2 7.1 12.6 3.2 7.6 5.6 7.4 8.3 5.8 7.8 8.5 6.3 7.2 5.9 9.9 4.6 9.8 6.2 6.1 6.0 12.6 10.5 6.2 12.6 8.6 5.1 7.1 18.9 27.1 13.4 24.2 28.5 24.3 19.8 19.7 14.9 20.9 18.7 11.2 18.5 54.2 16.3 20.1 33.8 39.9 43.5 25.8 22.3 36.3 21.4 37.1 25.9 22.4 20.3 63.2 30.5 24.0 23.5 22.0 31.6 16.7 23.7 16.3 60.7 17.1 22.5 29.7 42.7 24.8 21.4 28.4 26.8 29.8 37.9 23.0 10.6 13.4 23.0 12.3 25.3 25.1 18.0 17.3 9.5 21.2 24.9 18.3 14.0 26.7 25.0 17.7 37.5 26.7 18.5 37.4 26.6 18.9 8.3 11.3 11.4 10.8 15.8 13.0 11.3 11.8 12.1 12.9 13.3 11.7 3.1 13.2 15.7 10.2 13.8 7.1 4.2 5.8 5.0 5.3 4.1 5.3 5.6 5.4 5.6 4.6 6.0 7.1 25.4 19.2 33.4 15.7 33.8 13.0 18.4 15.3 21.1 17.9 14.7 20.6 28.4 14.3 19.8 11.0 10.4 19.5 37.7 10.1 15.6 23.5 13.9 17.9 46.2 23.9 9.0 37.6 12.1 12.9 20.1 25.8 23.9 20.8 52.4 30.6 16.1 11.5 26.5 28.6 12.5 16.9 6.1 17.7 12.1 9.4 32.0 23.9 10.6 18.7 34.5 12.4 43.3 15.6 25.9 16.1 11.2 23.7 36.5 23.3 10.3 15.8 21.2 17.7 6.6 29.3 21.5 73.3 50.2 25.4 15.9 14.6 30.1 33.4 20.3 12.2 NRIP2 DKFZP761G1913 ENSG00000053702 "Nuclear receptor interacting protein 2" Q9BQI9 12 2825348-2835544 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.4" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 6.2;Rod photoreceptor cells: 8.8;Sertoli cells: 26.3;Smooth muscle cells: 23.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "basophil: 3.7" "Lineage enriched" "Detected in single" 4 "granulocytes: 3.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039197, HPA039860" Enhanced Approved "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 34: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 20: HeLa - Mitochondria" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA039197: AB_10673416, HPA039860: AB_10794203" "unprognostic (3.28e-3)" "unprognostic (3.83e-1)" "prognostic unfavorable (8.05e-4)" "unprognostic (2.10e-2)" "unprognostic (8.11e-2)" "unprognostic (4.26e-3)" "unprognostic (5.66e-2)" "unprognostic (4.42e-3)" "unprognostic (2.89e-1)" "unprognostic (4.39e-2)" "prognostic favorable (8.69e-5)" "unprognostic (7.15e-2)" "unprognostic (2.82e-2)" "unprognostic (7.55e-2)" "unprognostic (5.23e-2)" "unprognostic (1.00e-1)" "unprognostic (8.97e-2)" 5.4 3.9 7.7 3.6 12.4 4.0 5.1 23.4 10.2 7.0 4.8 5.3 2.4 7.4 7.2 2.4 4.8 5.9 5.2 5.8 10.6 12.0 1.6 1.8 4.1 12.4 10.0 8.4 3.0 0.6 2.8 2.6 12.9 4.1 3.0 3.9 3.6 4.9 4.9 2.6 4.7 4.9 8.1 9.1 3.6 2.1 12.0 3.0 5.5 7.5 2.6 4.3 4.7 13.3 0.4 0.9 1.5 0.8 0.0 0.0 1.8 1.1 0.0 0.0 0.0 2.3 1.1 1.2 0.3 0.0 0.3 0.8 0.0 0.0 0.0 0.9 1.3 2.0 2.9 0.2 0.0 2.4 1.4 0.0 0.0 0.0 0.0 2.2 0.0 1.3 1.1 2.7 0.0 1.0 1.5 1.2 1.5 0.9 0.4 0.9 1.6 0.7 0.0 1.5 1.1 1.7 0.8 1.2 0.3 2.7 0.8 0.4 1.2 0.6 0.7 0.9 1.6 0.4 0.1 1.8 1.5 1.1 0.8 3.7 0.3 0.1 0.5 0.2 0.3 0.7 0.4 0.5 0.2 0.6 0.8 0.3 0.1 0.4 0.1 0.3 0.1 0.1 7.7 12.4 23.4 10.2 5.8 10.6 12.4 10.0 12.9 8.1 12.0 13.3 0.6 0.0 1.1 0.0 0.2 0.1 0.5 0.0 0.0 5.0 0.1 0.9 1.3 0.0 0.0 1.8 6.2 0.3 0.3 0.0 0.0 0.0 1.6 0.2 0.9 0.6 0.0 0.0 1.8 0.0 0.0 1.3 0.0 0.3 0.0 0.2 0.4 0.0 0.1 3.3 3.3 0.0 0.0 0.6 0.3 1.8 0.3 0.5 0.0 2.8 0.0 0.6 3.1 0.5 4.9 0.0 0.0 5.3 0.0 0.3 0.0 0.2 0.0 8.8 26.3 0.5 23.1 0.1 0.3 0.1 0.1 0.0 1.1 0.4 0.0 0.1 NUAK1 "ARK5, KIAA0537" ENSG00000074590 "NUAK family kinase 1" O60285 12 106063345-106138954 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endothelial cells: 111.7;Excitatory neurons: 150.5;Hepatic stellate cells: 136.3;Microglial cells: 93.7;Oligodendrocytes: 73.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 58.0;EFO-21: 55.1;RH-30: 77.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057143 Approved "Nucleoplasm,Nucleoli fibrillar center,Microtubules" Yes No "Cluster 47: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli fibrillar center" "Nucleoplasm, Microtubules" "HPA057143: AB_2683349" "unprognostic (4.20e-2)" "unprognostic (8.42e-2)" "unprognostic (3.71e-2)" "prognostic unfavorable (9.83e-4)" "unprognostic (4.13e-2)" "unprognostic (2.34e-1)" "unprognostic (1.43e-1)" "unprognostic (4.80e-2)" "unprognostic (9.91e-2)" "unprognostic (4.06e-3)" "unprognostic (3.29e-1)" "unprognostic (1.31e-1)" "unprognostic (1.93e-3)" "prognostic unfavorable (4.27e-4)" "unprognostic (2.31e-1)" "unprognostic (8.70e-2)" "unprognostic (4.47e-2)" 17.5 3.6 12.6 2.3 17.5 0.6 12.1 9.4 25.4 9.8 0.0 4.1 2.2 9.5 3.1 3.5 9.0 4.9 18.8 17.4 5.6 4.2 4.0 9.3 3.2 6.1 5.9 6.1 3.2 17.5 2.7 4.5 8.3 6.0 3.9 5.4 3.4 6.0 20.6 20.8 4.3 10.2 5.5 0.8 3.8 2.6 5.5 3.3 4.3 17.2 2.3 4.8 8.1 31.8 13.0 8.3 58.0 0.6 23.7 2.5 27.0 14.2 9.5 9.9 8.0 4.3 2.1 0.0 55.1 27.4 5.0 11.9 12.6 11.2 4.8 0.2 3.4 0.0 9.7 4.7 5.0 0.1 0.1 11.0 8.1 6.0 1.7 19.2 21.2 0.1 0.0 40.3 7.8 1.3 0.2 0.6 11.1 0.2 3.3 0.1 77.7 10.5 6.6 13.3 6.8 0.4 6.9 1.9 0.5 37.2 2.9 0.4 16.6 9.4 29.7 3.3 17.0 0.0 0.0 0.7 2.8 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 12.6 17.5 9.4 25.4 17.4 5.6 6.1 5.9 8.3 5.5 5.5 31.8 56.4 0.0 2.4 15.7 0.6 13.5 32.9 29.8 10.2 32.3 2.1 4.2 48.9 10.0 7.2 7.3 0.0 0.8 13.5 0.9 3.9 6.2 0.4 5.1 6.6 111.7 0.0 5.3 150.5 9.6 5.2 17.9 2.0 3.8 0.0 2.9 136.3 12.1 8.0 40.4 55.4 2.3 12.2 8.4 8.8 2.6 4.1 1.3 10.6 93.7 0.6 1.9 1.0 15.6 73.5 18.4 0.5 3.0 3.2 10.6 0.2 1.8 2.2 2.9 0.0 7.1 26.4 1.0 5.5 2.5 15.9 0.3 2.7 0.4 0.8 5.2 NUDCD2 "DKFZp686E10109, NudCL2" ENSG00000170584 "NudC domain containing 2" Q8WVJ2 5 163446526-163460102 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037384, HPA037385" Uncertain Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA 18000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Microtubules "Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA037384: AB_2675447, HPA037385: AB_10673630" "unprognostic (3.96e-1)" "unprognostic (3.69e-2)" "prognostic favorable (2.80e-4)" "unprognostic (1.46e-1)" "unprognostic (9.12e-2)" "unprognostic (3.75e-3)" "unprognostic (1.84e-1)" "unprognostic (4.74e-1)" "unprognostic (3.47e-2)" "unprognostic (7.63e-3)" "unprognostic (1.81e-1)" "unprognostic (2.45e-1)" "unprognostic (3.91e-2)" "unprognostic (1.34e-2)" "unprognostic (6.86e-2)" "unprognostic (3.40e-2)" "unprognostic (7.85e-2)" 13.9 11.8 11.1 13.2 13.2 11.7 11.2 13.2 14.0 8.1 10.2 11.2 14.5 10.2 6.4 12.8 9.7 5.7 8.3 11.0 11.4 11.7 15.3 8.7 15.1 12.8 12.6 8.9 15.4 6.8 9.3 10.3 13.7 8.9 6.1 7.3 14.0 3.6 20.9 10.7 13.3 6.3 12.8 12.8 11.8 10.4 12.5 8.1 9.4 5.0 9.8 9.2 10.3 17.7 62.3 32.3 23.5 37.1 14.1 10.4 31.3 24.6 7.0 8.7 13.9 28.6 46.3 35.5 57.5 4.0 39.8 30.6 12.6 13.9 10.7 70.6 36.6 32.4 42.0 26.4 15.3 37.3 35.3 3.8 7.7 8.4 12.1 12.3 9.8 39.1 35.1 42.6 8.9 25.2 55.1 80.9 25.8 18.4 35.2 45.7 39.2 63.0 8.0 14.3 59.6 33.6 38.7 24.7 66.3 13.8 47.2 37.8 21.9 29.4 43.8 32.6 56.7 35.0 63.8 61.5 34.2 63.2 31.4 49.9 48.3 32.5 60.2 59.8 76.5 91.7 84.0 71.8 68.0 68.0 88.7 79.0 6.2 83.8 51.5 81.1 83.5 69.1 11.1 13.2 13.2 14.0 11.0 11.4 12.8 12.6 13.7 12.8 12.5 17.7 58.0 28.9 23.8 9.1 47.5 59.4 54.9 92.6 42.7 30.7 70.4 88.6 43.1 35.8 53.1 38.6 22.9 118.7 43.8 25.4 148.7 63.6 95.1 57.6 44.1 47.4 43.8 78.4 18.8 64.0 55.8 48.6 32.1 38.3 31.6 35.7 36.0 55.1 69.8 10.1 14.0 45.3 87.5 41.8 42.7 24.5 51.6 35.7 49.8 11.2 46.4 51.4 52.5 11.1 36.0 59.9 33.6 51.1 55.5 95.2 31.5 112.5 65.1 38.2 39.5 51.3 46.5 87.6 44.2 56.0 67.6 56.8 48.3 64.8 68.6 59.3 NUDT15 "FLJ10956, MTH2" ENSG00000136159 "Nudix hydrolase 15" Q9NV35 13 48037726-48047221 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 79.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038968, HPA038969" Approved Supported Nucleoplasm Yes No "Cluster 22: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA038968: AB_10697402, HPA038969: AB_2676295" "unprognostic (9.48e-2)" "unprognostic (5.91e-3)" "unprognostic (2.64e-2)" "unprognostic (9.00e-3)" "unprognostic (4.99e-2)" "unprognostic (2.50e-3)" "unprognostic (2.29e-2)" "unprognostic (7.47e-3)" "prognostic unfavorable (1.25e-5)" "unprognostic (1.04e-1)" "unprognostic (8.50e-2)" "unprognostic (3.69e-1)" "unprognostic (4.63e-2)" "unprognostic (1.84e-3)" "unprognostic (3.35e-1)" "unprognostic (9.58e-2)" "unprognostic (8.93e-3)" 12.2 13.0 7.1 10.1 7.2 18.0 16.4 8.6 8.3 12.9 6.9 20.2 20.8 9.7 13.8 16.3 11.6 9.0 11.0 6.9 8.5 17.2 14.1 9.2 7.5 7.2 7.7 8.6 9.4 8.2 9.4 12.6 7.8 15.1 22.1 10.3 12.1 10.0 11.9 8.7 16.3 10.5 6.8 5.5 13.0 10.7 7.6 10.7 13.4 18.7 10.3 12.9 10.3 7.8 47.5 28.4 52.4 23.1 21.2 30.3 37.8 37.7 35.8 41.3 39.7 42.1 45.2 34.6 20.7 30.3 36.7 54.3 51.3 56.1 63.4 18.3 41.8 34.1 28.0 46.2 19.8 52.0 31.2 20.9 35.3 33.3 46.7 18.4 45.3 34.5 30.7 13.5 67.2 23.2 40.5 48.4 83.0 72.8 32.2 27.6 33.8 22.7 46.2 35.8 31.4 33.1 25.6 43.8 30.3 44.7 22.5 38.7 23.0 28.5 34.7 36.2 53.3 6.9 12.5 43.6 14.8 40.1 47.4 1.6 4.8 3.5 2.9 6.9 2.9 3.1 4.6 3.6 4.9 2.6 5.3 5.8 1.0 2.8 4.8 3.7 3.4 2.7 7.1 7.2 8.6 8.3 6.9 8.5 7.2 7.7 7.8 6.8 7.6 7.8 12.0 12.8 15.7 0.7 14.7 16.6 34.6 18.1 19.9 9.2 14.0 11.6 12.5 12.8 20.7 7.3 2.1 36.2 12.6 30.4 49.0 17.3 16.7 45.7 20.4 15.1 8.4 10.5 3.9 17.6 79.4 12.8 18.3 39.5 9.5 8.7 7.5 17.4 16.8 38.7 3.1 23.5 26.4 7.8 10.5 9.3 16.8 11.4 10.6 1.9 10.3 10.8 6.2 0.5 3.0 16.4 18.3 12.4 16.8 41.9 18.9 40.8 13.6 9.0 0.0 9.5 17.1 8.9 34.4 34.9 20.5 38.0 13.2 15.3 31.9 42.0 NUF2 "CDCA1, CT106, NUF2R" ENSG00000143228 "NUF2 component of NDC80 kinetochore complex" Q9BZD4 1 163266576-163355764 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 28.4;lymphoid tissue: 26.0;testis: 53.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 60.8;Spermatocytes: 208.2;Spermatogonia: 40.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "T-reg: 4.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA059692, HPA076604" Supported Nucleoplasm,Kinetochore,Cytosol Yes Yes "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Kinetochore, Cytosol" "HPA059692: AB_2684103, HPA076604: " "unprognostic (9.41e-2)" "unprognostic (2.61e-1)" "unprognostic (2.56e-1)" "unprognostic (5.32e-3)" "unprognostic (6.20e-2)" "unprognostic (3.77e-2)" "prognostic unfavorable (1.04e-5)" "prognostic unfavorable (9.16e-4)" "prognostic unfavorable (4.83e-4)" "unprognostic (8.45e-2)" "prognostic unfavorable (9.75e-4)" "unprognostic (3.70e-2)" "unprognostic (0.00e+0)" "unprognostic (9.79e-2)" "unprognostic (7.88e-2)" "unprognostic (2.69e-1)" "unprognostic (5.96e-2)" 0.8 0.6 0.5 6.9 0.8 28.4 1.2 0.5 0.8 1.0 0.4 4.2 4.3 1.1 0.3 5.8 0.4 1.0 0.3 0.6 0.6 0.3 0.7 0.9 18.2 0.9 0.8 0.4 0.2 0.6 0.2 4.7 0.9 0.4 5.3 1.5 0.9 0.3 0.1 4.1 4.3 2.3 0.7 3.6 2.6 53.5 0.8 26.0 0.5 0.2 16.7 1.8 1.8 1.0 90.8 30.8 80.5 33.9 2.5 8.1 43.6 55.9 39.3 88.9 77.3 23.7 77.7 77.4 45.5 22.6 37.0 51.6 49.6 21.0 111.5 81.4 35.6 30.3 34.8 34.4 0.3 53.0 60.2 1.0 2.0 45.0 31.6 16.8 41.1 74.5 58.1 103.9 85.0 17.6 97.3 70.6 43.9 66.1 47.0 65.0 70.3 68.4 25.3 12.4 59.9 68.9 29.9 32.2 30.6 49.7 49.3 109.5 29.4 65.9 73.8 50.1 115.1 73.9 111.5 148.9 22.0 42.9 74.7 1.4 0.1 1.3 1.2 0.0 0.5 0.6 1.8 1.2 0.2 0.7 1.2 1.0 0.4 1.8 0.1 0.3 4.3 0.4 0.5 0.8 0.5 0.8 0.6 0.6 0.9 0.8 0.9 0.7 0.8 1.0 0.5 0.0 0.5 1.3 5.3 5.9 1.9 4.2 1.2 1.2 1.3 2.7 0.9 0.0 3.3 0.0 0.0 21.7 3.6 2.6 0.0 0.8 17.7 2.5 2.5 1.8 0.0 60.8 1.1 0.2 29.7 3.4 5.6 3.0 4.5 18.3 3.3 0.4 14.0 0.0 1.4 3.3 0.0 5.2 3.6 21.4 2.5 3.1 0.0 1.0 0.9 2.0 6.2 0.5 3.6 0.2 0.1 2.2 17.8 0.8 0.9 0.2 0.7 2.3 6.6 0.9 4.2 208.2 40.3 10.6 2.4 4.0 5.0 1.7 9.0 3.8 NUFIP1 "NUFIP, Rsa1" ENSG00000083635 "Nuclear FMR1 interacting protein 1" Q9UHK0 13 44939249-44989471 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 63.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029958, HPA029959" Approved Enhanced Nucleoplasm,Nucleoli Yes No "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm Nucleoli "HPA029958: AB_10598911, HPA029959: AB_10602308" "unprognostic (2.01e-1)" "unprognostic (5.32e-3)" "unprognostic (1.58e-1)" "unprognostic (2.04e-1)" "unprognostic (1.70e-2)" "unprognostic (2.98e-3)" "unprognostic (2.32e-1)" "unprognostic (1.45e-2)" "unprognostic (2.91e-2)" "unprognostic (9.74e-3)" "unprognostic (4.52e-1)" "unprognostic (3.95e-2)" "unprognostic (3.73e-2)" "unprognostic (4.04e-2)" "unprognostic (4.89e-2)" "unprognostic (3.31e-1)" "unprognostic (5.24e-2)" 3.2 3.7 3.2 2.8 3.4 7.9 4.6 2.9 4.6 3.6 2.1 2.6 2.8 4.5 5.5 3.3 3.5 2.4 2.5 3.3 3.0 4.0 4.1 2.3 3.7 2.6 3.2 4.3 3.8 4.0 1.8 3.0 2.9 3.4 3.0 2.6 3.3 3.2 4.8 3.4 2.4 4.0 2.9 3.0 2.8 5.5 3.1 3.6 3.9 3.9 3.8 4.2 2.6 3.9 7.4 5.7 9.5 7.9 6.4 6.6 11.3 8.6 7.4 15.6 9.9 15.6 11.5 21.5 7.0 8.0 9.4 11.3 17.9 12.2 20.2 6.6 14.0 16.4 3.7 14.0 10.5 21.3 6.4 6.9 11.0 10.5 15.8 6.0 7.9 10.9 13.3 3.5 11.1 8.5 17.8 13.4 22.5 19.5 9.3 17.3 9.0 13.1 9.5 6.3 5.2 11.5 7.3 9.9 9.6 8.9 7.5 11.8 6.0 7.9 6.8 10.3 11.9 4.8 7.9 26.7 8.9 14.8 11.4 0.0 2.6 0.8 2.5 2.6 4.7 4.0 2.9 2.8 3.4 4.1 4.5 3.4 0.2 5.9 1.8 4.5 1.7 1.8 3.2 3.4 2.9 4.6 3.3 3.0 2.6 3.2 2.9 2.9 3.1 3.9 11.3 6.4 12.2 6.2 10.5 15.4 11.8 16.7 23.9 7.8 9.8 16.3 4.5 4.3 15.4 5.5 12.5 15.7 11.7 4.2 17.6 14.0 37.2 14.0 21.7 10.9 5.4 14.5 19.2 16.7 15.9 11.9 7.7 18.6 17.7 14.1 7.1 9.7 10.8 8.4 16.9 5.3 12.2 3.4 5.5 63.2 10.8 7.9 8.8 7.5 6.9 9.7 7.2 16.6 14.4 10.8 1.6 11.3 5.0 8.6 3.2 14.8 6.6 6.8 6.6 20.3 15.6 27.1 31.6 14.3 16.6 8.8 9.9 15.7 8.4 7.1 NUPR1 "COM1, p8" ENSG00000176046 "Nuclear protein 1, transcriptional regulator" O60356 16 28532708-28539008 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 1157.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 1162.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 14.3" "Lineage enriched" "Detected in single" 16 "granulocytes: 14.3" "Cell line enhanced" "Detected in many" "HHSteC: 280.6;hTCEpi: 446.5;SK-MEL-30: 344.9;T-47d: 199.1;U-87 MG: 173.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006349 Supported "Nucleoplasm,Cytokinetic bridge" Yes NA "Cluster 41: Basophils - Cellular respiration" "Cluster 25: Pancreas - Digestion" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "Cytokinetic bridge" "HPA006349: " "unprognostic (2.64e-2)" "unprognostic (2.77e-2)" "unprognostic (3.76e-2)" "unprognostic (1.86e-1)" "unprognostic (1.01e-1)" "unprognostic (4.40e-2)" "unprognostic (7.72e-3)" "unprognostic (5.77e-3)" "unprognostic (3.61e-2)" "unprognostic (2.77e-1)" "unprognostic (1.04e-2)" "unprognostic (2.32e-2)" "unprognostic (3.27e-2)" "unprognostic (1.51e-1)" "unprognostic (6.14e-2)" "unprognostic (6.36e-3)" "unprognostic (2.80e-2)" 190.1 270.7 66.9 32.2 71.3 1.2 185.8 70.4 83.7 148.5 55.3 221.1 12.3 137.8 81.8 110.1 146.3 70.7 108.8 64.7 82.8 87.8 345.4 164.4 29.9 83.9 77.0 188.9 1157.3 26.4 39.5 54.5 81.0 204.1 59.9 9.0 255.3 124.3 87.9 205.1 71.3 63.4 76.6 35.8 130.6 67.9 72.9 23.3 354.6 17.3 13.9 178.0 152.4 75.8 1.4 10.5 0.0 73.3 108.0 94.7 58.6 66.5 57.3 2.3 54.6 0.2 0.2 0.2 37.2 101.2 8.8 1.9 0.4 2.1 2.3 0.4 3.7 0.1 6.2 52.1 280.6 0.3 0.5 90.2 446.5 31.2 148.5 76.8 0.4 0.1 0.1 3.5 34.0 13.7 0.3 1.4 0.4 0.2 38.7 0.2 0.2 3.1 0.0 6.9 0.6 0.5 19.6 78.5 344.9 1.5 199.1 12.0 0.2 21.3 51.7 55.2 10.5 0.5 0.6 0.6 173.1 0.3 2.6 14.3 0.4 3.6 0.3 0.3 0.3 0.3 0.3 0.2 0.1 0.5 0.3 0.3 2.4 0.8 0.4 0.6 0.2 0.1 66.9 71.3 70.4 83.7 64.7 82.8 83.9 77.0 81.0 76.6 72.9 75.8 179.9 288.4 336.2 11.1 9.7 316.9 318.4 1162.8 253.8 3.5 379.6 348.1 146.1 121.5 639.3 323.7 2.1 142.3 5.2 276.3 21.5 242.0 14.8 186.4 291.8 165.4 61.1 53.5 0.2 567.2 73.6 407.5 58.6 597.3 20.3 198.3 262.3 734.9 296.8 1.7 0.5 464.9 225.9 45.2 115.2 61.0 528.8 100.6 154.7 3.7 6.3 200.2 1.0 0.5 4.7 222.5 71.1 704.5 7.7 374.2 0.9 272.6 514.1 5.3 203.8 129.5 368.3 9.8 4.9 211.2 531.8 707.8 20.0 66.3 376.1 483.8 NUSAP1 "ANKT, BM037, FLJ13421, LNP, PRO0310p1, Q0310, SAPL" ENSG00000137804 "Nucleolar and spindle associated protein 1" Q9BXS6 15 41320794-41381050 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 88.6;lymphoid tissue: 101.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 266.7;Extravillous trophoblasts: 121.2;Granulosa cells: 93.3;Spermatocytes: 99.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "basophil: 10.7;T-reg: 7.7" "Group enriched" "Detected in many" 15 "granulocytes: 10.7;T-cells: 7.7" "Low cell line specificity" "Detected in many" "HPA042904, HPA074847" Supported Approved "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" Yes Yes "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli, Nucleoli fibrillar center" "HPA042904: AB_2678220, HPA074847: AB_2732269" "unprognostic (1.19e-1)" "unprognostic (9.53e-3)" "unprognostic (1.65e-1)" "unprognostic (8.78e-2)" "unprognostic (3.46e-2)" "unprognostic (2.97e-2)" "unprognostic (1.16e-3)" "unprognostic (1.74e-3)" "unprognostic (1.37e-2)" "unprognostic (4.14e-1)" "prognostic unfavorable (6.27e-4)" "unprognostic (8.49e-3)" "prognostic unfavorable (6.82e-14)" "unprognostic (4.76e-3)" "unprognostic (1.23e-1)" "unprognostic (2.18e-1)" "unprognostic (1.22e-1)" 1.8 14.1 0.2 7.8 0.2 88.6 1.5 0.3 0.4 3.6 0.3 6.1 7.0 1.1 0.1 17.7 1.1 1.0 1.1 0.2 0.2 2.6 5.0 3.8 28.7 0.3 0.4 4.4 1.3 0.0 0.6 6.5 0.3 1.1 8.0 0.1 3.6 0.6 5.4 9.4 7.4 2.7 0.2 7.8 4.5 10.9 0.3 101.5 0.9 0.1 31.5 1.9 6.4 0.3 146.0 38.3 165.1 64.6 3.5 5.9 37.0 107.4 74.6 138.9 130.6 58.4 67.0 63.5 42.5 44.4 99.1 107.6 104.2 46.2 132.4 98.5 62.3 149.6 102.0 50.7 0.2 67.3 57.2 0.9 1.3 69.1 37.3 21.7 72.0 104.2 70.1 237.5 105.7 30.7 147.5 82.2 59.8 139.8 55.0 136.5 156.5 67.5 42.4 29.3 85.7 55.2 129.8 88.5 25.7 46.0 106.2 76.1 33.7 89.9 104.8 101.5 206.2 81.3 145.8 200.5 42.1 163.6 171.2 10.7 0.1 0.5 0.1 0.0 0.0 0.3 0.5 0.5 0.3 0.6 0.0 0.3 0.2 0.4 0.0 0.3 7.7 0.5 0.2 0.2 0.3 0.4 0.2 0.2 0.3 0.4 0.3 0.2 0.3 0.3 1.9 0.0 1.5 1.3 14.2 38.5 10.3 21.2 31.9 0.9 9.9 13.7 1.1 17.2 5.0 0.0 0.0 72.2 13.4 14.4 3.9 2.3 33.2 10.7 11.6 7.3 3.0 266.7 1.4 0.5 121.2 14.6 25.5 21.8 7.0 93.3 10.8 3.9 36.7 0.0 1.5 15.5 24.4 13.8 22.7 14.6 0.3 17.5 3.6 1.9 6.1 1.9 4.1 1.0 1.3 1.5 0.4 1.9 57.2 5.3 2.6 5.4 1.1 1.0 0.0 2.8 12.1 99.6 59.9 69.5 24.9 19.3 22.9 38.8 30.0 10.3 NXPH3 NPH3 ENSG00000182575 "Neurexophilin 3" O95157 17 49575871-49583827 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.4" "Cell type enhanced" "Detected in some" "Astrocytes: 14.0;Bipolar cells: 23.3;Fibroblasts: 7.6;Muller glia cells: 8.5;Peritubular cells: 14.3;Smooth muscle cells: 8.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "BEWO: 11.4;BJ: 3.2" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "cerebellum: 41.1" HPA073819 Approved "Vesicles,Mitotic spindle" "Secreted in brain" Yes NA "Cluster 21: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" Vesicles "Mitotic spindle" "HPA073819: " "unprognostic (2.39e-2)" "unprognostic (4.75e-2)" "unprognostic (2.33e-2)" "unprognostic (3.34e-1)" "unprognostic (1.92e-1)" "unprognostic (3.30e-1)" "unprognostic (1.97e-1)" "unprognostic (8.01e-2)" "unprognostic (4.00e-2)" "unprognostic (1.30e-1)" "unprognostic (2.03e-2)" "unprognostic (6.33e-2)" "unprognostic (4.62e-4)" "unprognostic (2.59e-2)" "unprognostic (2.66e-1)" "unprognostic (1.06e-1)" "unprognostic (5.05e-3)" 3.9 0.9 1.8 1.0 1.8 0.0 2.9 16.4 3.5 9.0 0.7 11.0 0.4 12.0 0.6 1.5 7.0 1.7 2.9 3.5 0.5 0.4 0.1 2.7 0.5 6.3 3.8 5.2 0.6 1.3 7.5 1.3 6.4 5.9 0.3 0.6 3.1 4.7 1.2 2.3 1.7 2.5 0.1 1.0 3.4 1.6 3.9 0.3 1.4 2.0 0.3 8.9 6.9 3.0 0.0 0.0 0.1 0.0 0.0 0.2 11.4 3.2 0.4 0.1 0.1 0.4 0.0 0.0 0.1 0.0 0.6 0.1 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.8 16.4 3.5 3.5 0.5 6.3 3.8 6.4 0.1 3.9 3.0 0.5 0.0 1.3 14.0 0.0 0.4 0.3 0.2 0.6 23.3 0.9 0.5 1.7 1.5 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.8 1.6 0.0 0.0 2.5 0.2 3.2 7.6 0.0 0.5 0.0 0.0 6.4 0.0 0.2 0.0 1.5 0.0 0.0 0.3 1.4 0.0 4.4 0.3 1.8 0.0 4.2 8.5 0.0 2.5 0.5 0.0 0.0 14.3 0.7 0.3 0.0 0.0 0.0 1.2 0.0 0.8 8.9 0.1 1.3 0.0 1.1 0.1 0.2 0.1 0.0 0.1 OAS3 ENSG00000111331 "2'-5'-oligoadenylate synthetase 3" Q9Y6K5 12 112938051-112976460 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Nucleotidyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "monocytes: 30.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 15.3" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 4 "BJ hTERT+ SV40 Large T+: 202.5;BJ hTERT+ SV40 Large T+ RasG12V: 224.5;GAMG: 89.8;RT4: 62.6" "Not detected" "Not detected" "HPA041253, HPA041372" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" Yes No 21000 "Cluster 51: Monocytes - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA041253: AB_10794990, HPA041372: AB_10795590" "unprognostic (8.47e-2)" "unprognostic (9.13e-2)" "unprognostic (1.27e-2)" "unprognostic (4.39e-3)" "unprognostic (2.59e-2)" "unprognostic (1.45e-1)" "unprognostic (4.14e-3)" "unprognostic (8.06e-3)" "unprognostic (3.19e-1)" "unprognostic (1.73e-2)" "unprognostic (2.29e-3)" "unprognostic (2.48e-1)" "prognostic unfavorable (2.23e-5)" "unprognostic (4.25e-2)" "unprognostic (1.37e-2)" "unprognostic (3.29e-2)" "unprognostic (2.93e-2)" 8.1 4.1 3.2 11.5 3.1 20.9 6.0 2.3 2.5 11.0 1.1 7.1 7.1 3.9 1.5 15.8 5.2 11.3 7.0 2.2 2.4 5.6 4.4 12.6 6.0 8.7 3.6 3.8 3.8 3.2 3.5 11.1 6.4 3.4 6.2 0.6 27.7 2.7 3.0 5.4 6.5 9.3 11.8 17.9 11.0 2.3 4.1 16.1 4.1 5.9 6.4 14.4 7.8 3.0 23.2 34.4 0.3 5.5 1.0 4.6 2.1 2.6 25.3 202.5 224.5 24.1 20.5 0.7 7.3 8.1 89.8 15.7 3.3 22.7 11.2 9.7 1.2 15.9 16.3 4.0 3.9 4.5 6.6 0.9 7.2 32.8 1.3 4.0 11.7 3.9 0.5 3.1 2.0 13.3 8.0 2.7 1.4 33.7 22.8 13.5 11.6 0.1 7.0 62.6 0.6 0.1 19.8 5.5 14.8 0.2 25.7 1.1 9.5 4.6 4.0 5.5 6.5 0.8 21.0 0.2 4.9 12.9 16.7 1.0 7.8 0.8 1.4 7.4 1.7 2.3 2.0 2.3 4.1 1.0 1.8 1.7 9.7 2.7 15.3 0.3 2.6 3.5 3.2 3.1 2.3 2.5 2.2 2.4 8.7 3.6 6.4 11.8 4.1 3.0 19.9 3.2 3.9 0.7 3.8 3.4 5.6 13.5 5.2 0.4 3.1 2.7 1.7 0.0 5.1 3.7 0.0 5.4 1.8 14.7 3.9 11.2 5.9 1.8 4.1 20.8 1.8 0.8 0.3 9.8 20.9 5.5 16.3 5.6 1.3 21.9 9.3 1.7 18.7 0.0 0.4 6.8 8.2 5.8 7.0 10.8 10.2 16.7 1.8 5.6 30.2 3.0 8.2 3.5 0.0 21.2 8.2 15.1 1.4 11.8 4.5 2.0 2.3 0.5 0.0 2.5 5.0 0.8 0.7 14.4 4.7 1.9 6.5 9.2 5.4 26.8 OGT "FLJ23071, HRNT1, MGC22921, O-GLCNAC, OGT1" ENSG00000147162 "O-linked N-acetylglucosamine (GlcNAc) transferase" O15294 X 71533104-71575892 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Host-virus interaction, Ubl conjugation pathway" "Chromatin regulator, Glycosyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030751, HPA030752, HPA030753, HPA030754, CAB034099" Approved Supported "Nucleoplasm,Plasma membrane" Yes No "Cluster 39: Non-specific - mRNA processing" "Cluster 50: Non-specific - Ribosome" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Plasma membrane" "CAB034099: AB_2157067, HPA030751: AB_10600217, HPA030752: AB_10601445, HPA030753: AB_2673594, HPA030754: AB_2673595" "unprognostic (1.37e-1)" "unprognostic (2.20e-1)" "unprognostic (2.32e-2)" "prognostic unfavorable (8.33e-4)" "unprognostic (3.40e-2)" "prognostic favorable (1.97e-4)" "unprognostic (9.56e-3)" "unprognostic (1.96e-3)" "unprognostic (5.58e-2)" "unprognostic (2.29e-1)" "unprognostic (1.06e-1)" "unprognostic (9.74e-3)" "prognostic unfavorable (2.36e-6)" "unprognostic (2.99e-3)" "unprognostic (2.28e-1)" "unprognostic (8.03e-3)" "prognostic favorable (6.85e-7)" 59.3 55.9 39.7 38.3 42.4 61.5 62.7 43.3 51.6 72.7 40.1 62.5 30.6 56.0 62.2 52.8 76.4 26.4 55.5 43.9 35.5 61.6 45.8 70.7 71.9 36.1 35.8 85.5 102.4 24.3 46.9 26.4 37.9 75.4 39.6 36.9 64.1 27.1 62.8 68.6 86.4 24.5 36.1 122.8 67.4 19.0 36.2 57.2 70.7 39.2 57.8 55.7 67.4 44.3 40.5 37.0 47.1 41.5 49.6 45.6 31.6 30.3 54.3 32.1 49.1 39.3 45.4 47.9 20.7 37.3 33.3 49.1 52.0 29.5 39.4 41.1 53.4 30.4 98.6 28.5 37.6 62.9 48.1 43.6 59.2 35.1 65.7 55.5 30.5 100.7 31.1 160.4 31.1 34.3 48.9 75.2 31.6 35.5 49.8 47.8 52.7 62.1 50.0 45.9 24.1 21.2 46.9 30.9 30.2 35.5 22.8 42.4 35.5 34.6 27.9 36.6 17.9 43.5 33.5 56.5 24.4 65.0 21.6 2.8 4.6 2.0 7.5 5.7 6.8 7.4 6.3 6.2 6.1 6.2 7.2 7.4 1.9 10.4 5.7 6.2 6.2 5.6 39.7 42.4 43.3 51.6 43.9 35.5 36.1 35.8 37.9 36.1 36.2 44.3 31.1 35.3 85.2 52.9 67.2 88.1 37.9 23.5 58.6 26.5 49.6 34.0 42.8 20.0 31.1 49.7 8.4 15.8 130.7 31.1 9.8 14.4 2.4 32.1 49.8 39.8 34.9 51.3 110.7 14.4 8.5 47.5 54.6 53.3 27.8 26.4 45.7 27.5 16.1 40.4 94.6 37.3 22.4 60.9 69.7 4.8 53.4 45.8 35.6 71.2 51.6 11.3 51.5 92.0 97.9 17.6 34.9 29.7 147.2 53.8 34.8 15.1 28.0 21.8 32.9 44.8 42.2 2.5 6.1 63.3 84.1 10.9 82.1 62.0 34.0 50.8 OLFM4 "GC1, GW112, OlfD" ENSG00000102837 "Olfactomedin 4" Q6UX06 13 53028813-53052057 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1296.1;pancreas: 671.4" "Cell type enhanced" "Detected in many" "Ductal cells: 497.1;Exocrine glandular cells: 900.9;Intestinal goblet cells: 791.9;Pancreatic endocrine cells: 933.7;Paneth cells: 556.9;Undifferentiated cells: 2419.9;Urothelial cells: 1989.0" "Group enriched" "Detected in many" 14 "colorectal cancer: 711.4;pancreatic cancer: 594.7;stomach cancer: 724.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 5.4;BJ hTERT+: 18.8;HaCaT: 26.4;OE19: 10.4;RPMI-8226: 6.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA077718 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" "Secreted to digestive system" Yes NA 9300 "Cluster 56: Intestine - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "Cytokinetic bridge, Cytosol" "HPA077718: AB_2732358" "prognostic favorable (8.77e-4)" "unprognostic (4.84e-2)" "unprognostic (1.65e-3)" "unprognostic (2.33e-1)" "unprognostic (7.24e-2)" "unprognostic (1.34e-1)" "unprognostic (3.74e-2)" "unprognostic (5.16e-2)" "unprognostic (1.40e-1)" "unprognostic (1.22e-1)" "unprognostic (4.78e-2)" "unprognostic (1.28e-1)" "unprognostic (1.50e-1)" "unprognostic (1.29e-2)" "unprognostic (1.33e-1)" "unprognostic (4.37e-2)" "unprognostic (4.84e-3)" 1.9 0.1 0.2 195.4 0.5 126.0 6.8 0.1 0.5 7.9 0.2 451.6 1211.9 5.5 3.5 0.8 8.3 10.4 0.8 0.2 0.4 26.9 0.9 3.8 1.4 0.1 0.2 0.2 671.4 0.0 0.5 0.6 0.2 92.4 568.7 0.4 16.2 0.9 0.6 0.4 1296.1 52.6 0.2 18.0 16.1 0.3 0.2 4.2 0.4 2.1 0.2 127.0 285.6 0.2 0.0 0.0 0.1 0.0 0.0 0.0 5.4 2.4 18.8 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 26.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 10.4 0.0 0.0 0.8 6.2 0.2 0.0 1.1 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.6 0.9 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.1 0.5 0.2 0.4 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.3 3.8 0.1 168.5 0.3 0.0 0.0 9.8 2.5 0.5 0.0 11.9 139.8 0.0 0.0 0.0 98.7 1.9 497.1 0.2 13.5 0.5 1.4 92.3 0.8 1.0 900.9 0.0 1.5 0.0 17.6 0.0 0.0 0.0 0.0 0.1 0.0 0.3 791.9 2.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 10.3 4.0 0.0 0.0 0.2 933.7 556.9 0.0 0.4 209.4 300.6 0.0 0.5 0.2 0.0 2.1 9.2 0.0 0.1 0.0 0.0 0.0 3.1 0.2 2419.9 1989.0 OPN1SW "BCP, BOP, CBT" ENSG00000128617 "Opsin 1, short wave sensitive" P03999 7 128772485-128775794 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 84 "retina: 41.0" "Cell type enriched" "Detected in some" 12 "Cone photoreceptor cells: 41.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "LHCN-M2: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA013562, HPA014083" Enhanced Approved "Nucleoplasm,Nuclear bodies,Cytokinetic bridge,Cytosol" Yes NA "Cluster 79: Retina - Phototransduction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "Nuclear bodies, Cytokinetic bridge, Cytosol" "HPA013562: AB_2668850, HPA014083: AB_2668938" "unprognostic (2.88e-1)" "unprognostic (5.17e-2)" "unprognostic (2.22e-2)" "unprognostic (1.33e-2)" "unprognostic (2.55e-2)" "unprognostic (2.16e-1)" "prognostic unfavorable (8.50e-5)" "unprognostic (1.13e-1)" "unprognostic (1.27e-1)" "unprognostic (6.33e-2)" "unprognostic (3.79e-1)" "unprognostic (6.05e-2)" "prognostic unfavorable (2.26e-8)" "prognostic unfavorable (5.98e-8)" "unprognostic (2.53e-1)" "unprognostic (8.99e-2)" "prognostic unfavorable (9.33e-4)" 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.2 0.4 0.0 0.4 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 41.0 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.0 0.0 41.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ORC6 ORC6L ENSG00000091651 "Origin recognition complex subunit 6" Q9Y5N6 16 46689643-46698394 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.3;lymphoid tissue: 7.4;testis: 9.6" "Cell type enhanced" "Detected in many" "Granulosa cells: 56.7;Spermatocytes: 102.6;Spermatogonia: 108.9;Theca cells: 47.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016330, HPA072587" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center" Yes No "Cluster 24: B-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli fibrillar center" "CAB016330: AB_670295, HPA072587: AB_2686537" "unprognostic (3.47e-2)" "unprognostic (8.99e-3)" "unprognostic (2.92e-1)" "unprognostic (4.47e-2)" "unprognostic (2.27e-1)" "unprognostic (2.19e-2)" "unprognostic (3.15e-6)" "unprognostic (1.36e-2)" "prognostic unfavorable (3.53e-4)" "prognostic favorable (1.48e-4)" "unprognostic (1.50e-4)" "unprognostic (3.97e-2)" "unprognostic (3.90e-14)" "unprognostic (2.08e-1)" "unprognostic (4.24e-1)" "unprognostic (2.79e-1)" "unprognostic (5.98e-2)" 0.3 0.7 2.0 2.2 1.6 10.3 0.6 1.5 1.9 0.7 1.0 1.7 1.5 0.8 1.1 4.1 0.4 0.6 1.5 1.9 1.8 0.4 0.9 0.6 7.4 1.5 1.9 0.4 0.3 0.7 0.6 3.3 1.7 0.3 1.9 0.3 0.7 0.2 0.1 1.1 1.5 1.0 1.6 2.4 0.8 9.6 1.8 6.2 0.5 0.3 7.3 1.2 1.3 1.8 28.6 27.4 43.7 33.9 5.4 6.8 31.6 54.2 20.2 59.3 30.9 39.3 18.0 35.6 27.1 10.5 29.1 29.9 57.9 15.1 50.4 17.2 46.4 27.9 13.2 40.1 6.6 46.5 23.7 1.8 2.6 32.4 17.1 9.3 20.0 30.1 36.0 17.4 35.9 26.9 65.6 60.7 48.1 20.7 76.0 78.6 80.6 35.8 14.9 9.8 52.2 30.4 24.5 29.8 18.1 34.9 15.6 37.9 11.6 53.7 34.6 33.6 51.8 12.5 18.9 123.2 22.2 29.5 40.1 0.0 0.3 0.3 0.9 0.7 0.4 0.7 0.5 0.5 0.6 1.4 0.8 0.3 0.0 0.8 0.8 1.0 1.2 0.7 2.0 1.6 1.5 1.9 1.9 1.8 1.5 1.9 1.7 1.6 1.8 1.8 1.6 3.2 14.5 1.0 8.8 6.6 2.2 3.6 8.6 6.6 4.1 5.8 3.7 1.5 6.3 5.5 4.2 39.3 6.0 9.5 1.9 2.5 13.2 6.5 7.5 4.3 1.8 45.4 6.3 0.7 40.9 8.0 7.1 9.4 1.3 56.7 0.7 9.9 15.7 11.8 2.7 12.4 6.1 3.8 11.9 8.9 2.8 7.7 33.8 2.8 1.2 2.5 2.1 0.0 2.0 2.1 1.4 3.4 18.5 2.6 2.3 1.0 10.7 10.2 0.0 5.1 7.3 102.6 108.9 16.9 6.0 10.9 7.5 47.5 14.4 2.7 OTUD7B "CEZANNE, ZA20D1" ENSG00000264522 "OTU deubiquitinase 7B" Q6GQQ9 1 149937812-150010726 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 43.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 106.3;Oligodendrocytes: 176.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027045, HPA076357" Supported Uncertain "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 41: Basophils - Cellular respiration" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA027045: AB_1854847, HPA076357: " "unprognostic (2.17e-2)" "unprognostic (2.93e-2)" "unprognostic (1.90e-1)" "prognostic favorable (7.47e-4)" "unprognostic (1.51e-1)" "unprognostic (1.05e-1)" "unprognostic (1.23e-3)" "unprognostic (1.46e-2)" "prognostic favorable (5.09e-5)" "unprognostic (4.90e-2)" "unprognostic (7.72e-2)" "unprognostic (8.94e-2)" "unprognostic (3.37e-2)" "unprognostic (1.67e-2)" "unprognostic (1.18e-1)" "unprognostic (4.52e-2)" "unprognostic (1.58e-2)" 11.7 7.7 21.0 3.8 39.2 1.1 7.8 28.7 18.5 9.9 6.8 7.6 6.2 10.5 3.8 7.7 9.3 4.8 7.1 15.3 22.1 5.6 10.7 7.3 1.9 41.4 37.2 10.9 6.1 10.9 3.4 7.1 35.5 6.6 7.1 10.1 7.8 7.5 18.6 5.8 6.2 10.8 27.9 3.6 6.7 12.7 31.7 2.1 6.7 16.2 3.2 6.3 5.2 43.0 17.2 13.5 9.3 15.6 12.0 11.1 8.8 11.8 17.3 14.0 9.6 10.0 13.6 0.2 7.5 21.7 6.3 13.4 13.2 13.1 14.6 16.5 6.7 6.6 18.9 6.8 12.8 7.6 6.9 12.4 9.9 23.7 20.6 10.9 11.5 2.0 18.4 18.1 10.1 17.5 1.3 2.1 11.9 12.8 13.1 1.8 12.9 4.4 5.4 23.2 6.0 11.4 20.8 15.2 18.5 12.1 12.6 4.0 13.9 14.4 13.2 9.8 14.0 19.1 20.0 2.0 12.8 2.2 24.1 2.0 0.0 0.4 0.7 0.0 0.5 0.1 0.3 0.4 0.0 0.1 0.2 0.3 0.3 0.4 0.0 0.1 0.1 0.0 21.0 39.2 28.7 18.5 15.3 22.1 41.4 37.2 35.5 27.9 31.7 43.0 10.2 35.3 11.7 56.8 3.0 15.9 22.7 8.7 13.1 28.0 18.3 9.3 22.2 12.8 15.3 11.0 106.3 23.5 5.1 41.1 7.9 14.5 63.4 21.8 17.8 16.7 17.4 14.9 20.6 11.1 11.6 14.8 21.4 40.2 0.0 22.0 20.3 33.0 3.1 23.5 24.6 15.8 8.2 0.8 5.9 79.4 14.6 2.4 37.4 22.5 4.3 23.6 15.5 33.2 176.8 20.6 21.3 23.0 4.7 20.2 17.1 11.5 17.4 66.9 0.0 19.8 17.9 11.1 7.2 11.8 16.6 21.2 7.5 11.1 11.1 34.0 OVOL1 HOVO1 ENSG00000172818 "Ovo like transcriptional repressor 1" O14753 11 65787063-65797214 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 57.2;skin 1: 51.0;testis: 35.5" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 113.2;Squamous epithelial cells: 130.8;Syncytiotrophoblasts: 348.9;Urothelial cells: 114.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 19.0;BEWO: 52.2;CACO-2: 13.6;HaCaT: 31.4;MCF7: 12.6;RT4: 31.2;SK-BR-3: 24.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA003984 Uncertain Approved Nucleoplasm Yes NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA003984: AB_1854854" "unprognostic (4.26e-3)" "unprognostic (3.39e-1)" "unprognostic (3.96e-2)" "prognostic unfavorable (1.87e-4)" "unprognostic (1.37e-1)" "unprognostic (1.55e-1)" "unprognostic (3.37e-1)" "unprognostic (1.26e-2)" "unprognostic (1.95e-1)" "unprognostic (2.31e-2)" "unprognostic (2.01e-3)" "unprognostic (1.91e-1)" "prognostic favorable (1.00e-13)" "unprognostic (4.26e-2)" "unprognostic (3.51e-2)" "unprognostic (2.42e-1)" "unprognostic (9.04e-3)" 0.1 0.0 0.0 1.0 0.1 0.1 2.8 0.2 0.1 13.6 0.0 10.3 15.5 0.5 0.1 57.2 0.6 0.9 0.0 0.1 0.0 7.4 0.2 0.3 0.0 0.0 0.0 0.0 9.1 15.0 0.1 6.9 0.0 1.4 8.3 0.1 8.8 1.0 0.1 51.0 9.1 0.3 0.0 0.1 1.6 35.5 0.0 0.4 1.3 0.0 5.5 27.4 21.3 0.1 19.0 0.0 0.0 0.0 0.0 0.0 52.2 0.0 0.0 0.0 0.0 13.6 5.0 0.0 0.1 0.0 0.0 31.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 9.7 0.1 0.3 0.0 0.1 1.4 31.2 0.2 0.1 0.0 24.0 0.2 5.4 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 3.3 0.3 2.3 26.6 62.6 14.5 54.1 0.0 59.4 25.4 0.5 7.2 13.0 3.7 0.0 19.5 1.3 57.6 0.0 2.5 81.9 76.2 11.7 1.8 31.6 0.0 0.1 3.8 14.0 0.9 0.0 113.2 2.5 0.0 0.0 0.1 2.1 0.0 0.1 54.9 20.3 0.0 1.4 87.2 1.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 44.5 1.9 3.0 34.1 39.1 6.7 11.3 0.0 0.0 0.0 1.1 83.9 4.8 130.8 57.4 348.9 1.7 0.0 52.0 114.9 P4HA1 "C-P4Halpha(I), P4HA" ENSG00000122884 "Prolyl 4-hydroxylase subunit alpha 1" P13674 10 73007217-73096974 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 494.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007599, HPA026593" Enhanced Supported "Endoplasmic reticulum,Vesicles,Mitochondria" "Intracellular and membrane" Yes No 60000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" "Vesicles, Mitochondria" "HPA007599: AB_1854891, HPA026593: AB_1854892" "prognostic unfavorable (9.01e-4)" "prognostic unfavorable (3.19e-5)" "unprognostic (2.76e-3)" "unprognostic (3.04e-1)" "unprognostic (1.69e-2)" "prognostic unfavorable (1.19e-5)" "unprognostic (2.30e-1)" "prognostic unfavorable (5.10e-4)" "unprognostic (1.28e-1)" "unprognostic (2.29e-1)" "prognostic unfavorable (2.85e-4)" "unprognostic (9.15e-2)" "prognostic unfavorable (9.40e-9)" "unprognostic (3.14e-1)" "unprognostic (4.22e-2)" "unprognostic (1.02e-2)" "unprognostic (5.75e-2)" 28.1 26.0 25.7 20.8 26.4 15.5 26.3 29.6 58.5 31.9 34.7 16.3 11.0 27.0 18.9 10.1 41.1 26.3 38.7 26.5 27.1 35.8 72.8 27.8 16.2 32.9 30.0 34.9 17.5 17.0 11.6 65.3 33.0 20.0 17.4 33.3 13.0 18.4 110.9 17.4 14.4 28.5 30.2 19.6 19.8 19.3 30.1 12.9 13.9 54.0 14.6 29.6 18.2 39.0 84.0 21.2 60.1 117.6 181.2 138.3 50.1 239.9 215.8 90.8 215.8 35.6 63.6 28.4 89.7 239.0 55.1 92.5 38.3 87.7 197.1 36.5 14.5 24.4 18.6 42.5 75.3 45.1 16.4 84.5 50.3 77.7 101.6 494.2 43.5 23.8 38.3 14.7 79.3 22.4 17.9 42.9 21.6 38.9 92.3 16.4 40.2 52.4 51.0 35.6 5.5 33.7 49.2 143.2 58.3 135.0 21.9 41.9 41.9 110.5 44.8 31.3 56.9 81.8 31.3 13.7 198.1 64.5 54.9 1.1 18.8 14.9 6.7 23.5 8.7 8.2 8.1 7.9 20.7 9.2 5.9 6.1 10.4 5.2 25.7 16.6 10.7 9.1 25.7 26.4 29.6 58.5 26.5 27.1 32.9 30.0 33.0 30.2 30.1 39.0 29.0 6.4 28.4 87.1 31.7 36.3 33.0 138.0 22.2 13.5 23.8 15.7 42.0 7.2 69.2 23.9 27.1 31.5 24.9 25.1 0.0 33.1 16.8 85.6 89.2 25.9 10.3 7.2 48.8 19.5 116.4 67.7 14.3 131.4 40.5 16.9 20.0 29.8 43.9 11.8 41.6 9.5 46.8 54.1 75.7 8.1 51.9 51.5 44.4 62.8 39.0 34.0 6.2 86.5 44.8 36.6 27.1 47.0 32.9 24.9 13.5 25.1 94.6 17.2 39.5 37.0 44.7 61.7 34.0 9.8 23.9 33.2 27.7 31.1 7.0 17.6 PAICS "ADE2H1, AIRC, PAIS" ENSG00000128050 "Phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase" P22234 4 56435741-56464578 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" "Decarboxylase, Ligase, Lyase, Multifunctional enzyme" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 157.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035895, HPA041538" Approved Approved Cytosol Yes No 490000 "Cluster 30: Non-specific - Translation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA035895: AB_10669660, HPA041538: AB_2677540" "unprognostic (2.59e-3)" "unprognostic (7.90e-3)" "unprognostic (3.84e-3)" "unprognostic (2.88e-2)" "unprognostic (9.85e-2)" "unprognostic (2.82e-3)" "prognostic unfavorable (1.50e-4)" "unprognostic (8.07e-3)" "unprognostic (1.23e-2)" "prognostic favorable (8.44e-4)" "unprognostic (1.48e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (5.85e-5)" "unprognostic (7.11e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (2.41e-4)" "unprognostic (2.16e-1)" 24.5 40.2 22.7 40.1 26.7 46.8 54.6 28.3 25.0 29.3 21.6 42.8 32.1 29.7 22.1 36.3 35.4 17.8 19.7 20.3 27.8 42.7 109.7 14.1 51.3 26.0 30.1 30.7 21.7 39.5 17.7 45.9 26.1 31.0 54.7 30.4 26.4 25.8 32.4 37.6 30.8 35.7 25.6 18.3 20.7 29.5 26.8 56.4 32.4 24.1 64.5 37.4 25.4 27.2 239.3 175.3 354.3 220.6 74.3 166.1 304.0 201.7 145.1 282.5 276.0 280.5 275.7 548.0 228.3 136.0 154.1 143.6 565.5 293.0 480.8 110.4 198.8 298.7 259.5 313.4 141.8 537.1 127.6 141.9 207.9 301.0 225.0 155.7 235.4 308.6 524.7 198.5 246.8 159.3 621.5 267.2 407.5 454.8 216.5 496.2 151.7 361.5 268.4 164.5 378.8 226.4 198.6 273.7 124.3 287.2 181.2 169.8 127.7 222.6 290.1 221.8 419.0 139.1 128.2 571.1 234.8 385.2 251.0 6.0 5.2 0.4 5.2 8.7 15.0 17.8 14.4 9.2 15.3 11.0 17.4 15.5 1.1 15.9 6.9 17.0 11.2 8.7 22.7 26.7 28.3 25.0 20.3 27.8 26.0 30.1 26.1 25.6 26.8 27.2 16.4 22.4 22.9 17.0 35.7 56.6 71.9 66.0 54.1 27.4 35.8 37.5 23.3 50.1 32.3 33.1 6.2 134.4 15.3 20.5 37.2 45.0 69.4 15.2 49.1 25.1 24.7 80.8 9.1 26.3 157.5 34.2 15.3 23.3 21.0 69.1 13.2 78.7 51.5 28.6 14.6 41.0 34.6 16.1 17.2 10.6 29.8 16.1 17.8 6.5 20.2 14.0 6.2 13.0 12.2 27.4 18.6 23.3 48.1 81.7 15.9 47.7 17.9 24.6 0.0 31.3 29.2 40.0 50.3 53.1 50.4 54.6 16.8 66.4 69.7 48.9 PAPSS1 "ATPSK1, PAPSS" ENSG00000138801 "3'-phosphoadenosine 5'-phosphosulfate synthase 1" O43252 4 107590276-107720234 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 444.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "basophil: 321.8;eosinophil: 359.8" "Lineage enriched" "Detected in all" 6 "granulocytes: 359.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049781 Approved Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes No 13000 "Cluster 2: Granulocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 44: Endometrium - Transcription" "Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA049781: AB_2680879" "unprognostic (1.36e-2)" "unprognostic (5.03e-2)" "prognostic favorable (9.14e-4)" "prognostic favorable (8.58e-4)" "unprognostic (1.63e-2)" "unprognostic (1.08e-1)" "prognostic unfavorable (2.70e-5)" "unprognostic (1.58e-2)" "unprognostic (1.05e-1)" "unprognostic (8.92e-2)" "unprognostic (1.42e-1)" "unprognostic (5.76e-2)" "unprognostic (6.23e-3)" "unprognostic (1.29e-1)" "unprognostic (1.72e-1)" "unprognostic (1.61e-2)" "unprognostic (1.38e-1)" 26.3 14.2 36.8 30.8 43.9 26.0 49.9 46.4 50.0 49.6 26.5 20.4 16.0 47.1 43.0 36.2 48.4 26.4 15.9 41.9 40.8 31.7 10.3 44.4 32.9 53.2 41.4 29.2 49.3 26.9 15.8 17.2 51.8 41.1 24.7 22.3 66.0 25.9 6.1 49.7 15.8 33.6 51.1 17.4 62.8 17.0 41.8 35.4 20.3 9.9 51.7 31.7 23.7 66.3 33.6 29.7 49.1 62.1 59.1 74.0 39.6 42.4 77.2 39.4 53.1 45.7 46.7 51.3 26.0 76.1 30.4 40.7 46.8 81.6 50.5 124.2 35.5 60.4 62.6 103.0 32.3 93.0 99.8 61.7 41.2 45.7 37.1 95.2 88.7 63.9 13.6 97.0 111.6 50.7 77.3 28.2 52.6 35.3 33.1 62.4 78.0 15.0 59.6 45.6 55.5 81.4 42.9 63.3 51.9 61.9 37.9 14.1 52.9 49.3 51.0 33.6 35.4 76.9 57.2 48.7 60.1 69.3 79.2 321.8 49.9 359.8 15.6 56.2 18.8 44.8 21.2 18.0 51.4 26.4 13.2 14.9 55.5 27.6 60.8 9.8 39.9 36.7 36.8 43.9 46.4 50.0 41.9 40.8 53.2 41.4 51.8 51.1 41.8 66.3 19.7 96.1 20.2 41.4 25.4 32.0 36.3 73.2 33.6 19.9 48.4 41.5 7.4 50.1 92.3 57.0 10.4 20.6 7.0 10.5 17.6 36.8 6.2 124.2 84.6 25.1 23.4 15.3 112.2 44.7 48.7 35.2 62.2 444.3 42.5 25.0 20.3 10.2 55.1 30.3 64.7 17.5 32.6 46.5 27.8 6.7 18.0 53.5 60.5 29.0 37.4 35.0 10.3 100.0 150.3 33.6 9.1 25.6 86.4 29.1 6.9 28.8 110.0 13.3 26.3 45.2 29.1 19.6 14.7 62.9 40.9 8.9 22.2 19.2 14.8 29.4 PARP3 "ADPRT3, ADPRTL3, ARTD3, hPARP-3, IRT1, pADPRT-3" ENSG00000041880 "Poly(ADP-ribose) polymerase family member 3" Q9Y6F1 3 51942345-51948867 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 33.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020984, HPA067657" Supported Supported "Nucleoplasm,Nuclear bodies" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Nuclear bodies" "HPA020984: , HPA067657: AB_2685881" "prognostic favorable (6.39e-5)" "unprognostic (1.25e-1)" "unprognostic (1.54e-2)" "unprognostic (2.85e-2)" "unprognostic (7.31e-2)" "unprognostic (1.56e-1)" "unprognostic (4.13e-1)" "unprognostic (3.53e-2)" "unprognostic (2.26e-1)" "unprognostic (2.01e-1)" "unprognostic (7.44e-3)" "unprognostic (4.30e-1)" "prognostic favorable (1.25e-8)" "unprognostic (5.63e-2)" "unprognostic (1.77e-1)" "unprognostic (1.40e-2)" "unprognostic (4.65e-3)" 16.0 33.4 12.7 9.9 13.5 3.1 15.3 12.9 14.6 9.6 14.4 17.1 28.1 11.4 5.9 10.4 11.2 11.3 13.6 11.6 14.2 21.2 29.2 13.4 10.9 13.8 14.9 8.9 4.4 35.8 10.9 5.9 13.7 14.6 10.2 4.7 14.5 15.5 15.8 7.5 25.2 9.3 12.9 14.8 16.4 5.4 14.9 8.2 19.6 17.6 8.0 15.4 10.8 12.4 10.0 6.6 2.0 17.3 17.8 30.0 4.8 15.4 29.0 23.1 24.9 3.9 28.1 14.1 4.5 29.4 12.6 1.6 5.0 14.5 9.1 34.8 1.2 7.8 15.1 13.2 18.8 5.3 10.9 24.4 12.4 16.2 9.1 35.7 10.8 10.2 3.5 14.7 19.9 3.4 4.6 12.5 2.4 4.2 16.4 7.3 2.8 13.9 14.0 13.5 2.0 6.4 16.3 4.8 10.7 1.4 6.5 5.9 24.0 42.5 9.9 7.4 10.4 22.5 26.0 6.0 27.2 14.4 13.6 0.0 1.6 1.2 2.4 3.0 2.2 6.3 2.6 1.8 2.6 2.5 3.6 3.5 0.1 5.7 1.6 0.9 3.2 1.8 12.7 13.5 12.9 14.6 11.6 14.2 13.8 14.9 13.7 12.9 14.9 12.4 5.3 6.4 10.0 6.2 8.1 2.7 10.6 15.9 21.1 2.0 8.6 8.9 7.4 8.6 8.6 0.0 0.0 0.6 2.1 13.1 7.9 9.7 7.8 2.4 3.8 5.3 3.0 1.7 2.6 6.3 0.4 4.7 17.3 2.7 4.5 0.8 2.5 9.5 3.7 0.0 3.0 11.3 6.1 3.2 2.2 15.3 4.7 3.7 7.2 3.7 5.0 3.8 0.0 1.0 1.8 11.5 6.5 1.5 4.9 4.3 33.4 20.6 9.5 2.1 6.6 4.1 5.7 3.4 3.3 7.8 1.4 0.5 5.9 1.6 13.8 9.3 PARP4 "ADPRTL1, ARTD4, p193, VAULT3, VPARP, VWA5C" ENSG00000102699 "Poly(ADP-ribose) polymerase family member 4" Q9UKK3 13 24420931-24512778 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Ribonucleoprotein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "granulocytes: 99.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011739 Approved Supported Nucleoplasm,Cytosol Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm Cytosol "HPA011739: AB_1854986" "unprognostic (1.61e-1)" "unprognostic (2.34e-2)" "unprognostic (1.62e-2)" "unprognostic (4.35e-2)" "unprognostic (2.46e-1)" "unprognostic (1.21e-1)" "unprognostic (1.20e-1)" "unprognostic (2.52e-1)" "unprognostic (2.45e-1)" "unprognostic (2.02e-2)" "unprognostic (4.12e-3)" "unprognostic (2.97e-2)" "prognostic favorable (1.21e-5)" "unprognostic (3.23e-2)" "unprognostic (1.71e-1)" "unprognostic (3.80e-2)" "unprognostic (2.84e-3)" 18.6 22.8 8.4 24.2 11.9 22.1 16.7 11.2 8.2 24.3 12.1 38.7 38.9 17.9 18.0 22.0 21.1 29.5 12.7 7.5 10.4 26.9 24.9 28.7 23.6 15.6 11.3 18.6 14.8 18.5 5.8 15.9 15.2 13.1 39.5 8.3 16.8 18.6 6.4 11.0 39.1 19.5 11.3 26.3 34.4 9.0 11.8 21.6 21.2 11.3 25.2 28.3 14.0 15.6 42.9 37.7 18.1 32.7 48.7 68.8 15.3 48.7 63.5 41.8 37.1 15.5 108.5 32.0 47.3 44.5 46.3 48.5 27.2 49.4 34.1 73.7 19.0 45.9 33.0 35.9 27.8 59.3 43.3 39.9 16.3 34.6 18.3 81.4 69.7 24.5 13.2 13.8 50.2 19.9 37.6 28.5 20.5 100.6 45.9 35.0 33.8 45.0 77.6 86.7 16.4 20.9 35.7 14.2 33.5 23.4 7.1 48.2 99.7 18.9 19.8 24.4 50.4 15.6 19.3 41.4 34.3 30.6 42.1 50.0 21.1 45.9 20.4 25.7 20.4 14.2 16.8 20.5 27.9 8.0 12.2 14.8 24.0 21.1 34.6 10.4 21.9 20.1 8.4 11.9 11.2 8.2 7.5 10.4 15.6 11.3 15.2 11.3 11.8 15.6 20.5 51.3 51.8 21.2 20.5 2.8 6.9 29.2 6.2 6.3 10.2 5.8 17.6 17.2 52.6 25.8 2.1 5.0 33.8 74.2 5.9 26.1 5.4 35.9 19.4 19.8 4.9 13.9 1.5 22.5 8.9 18.3 42.8 50.9 99.2 30.7 31.1 16.0 17.7 1.7 2.1 27.0 18.3 23.4 6.9 4.7 11.8 35.3 8.8 36.5 37.1 6.7 36.0 21.1 40.8 30.9 53.8 8.2 27.0 10.6 59.7 18.2 69.7 7.4 6.6 12.2 10.4 2.5 8.9 13.5 3.8 1.9 28.9 24.1 30.8 20.5 PARP6 "ARTD17, pART17" ENSG00000137817 "Poly(ADP-ribose) polymerase family member 6" Q2NL67 15 72241181-72272999 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 178.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026991 Approved Approved "Plasma membrane" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "HPA026991: AB_1854989" "unprognostic (3.88e-2)" "prognostic favorable (3.17e-5)" "prognostic unfavorable (3.37e-4)" "unprognostic (3.36e-1)" "unprognostic (7.13e-2)" "unprognostic (3.05e-1)" "unprognostic (2.37e-2)" "unprognostic (1.33e-1)" "unprognostic (2.00e-1)" "unprognostic (2.64e-1)" "unprognostic (8.55e-2)" "unprognostic (6.92e-2)" "prognostic unfavorable (8.02e-8)" "unprognostic (6.81e-2)" "unprognostic (1.14e-1)" "unprognostic (1.45e-1)" "unprognostic (4.42e-2)" 20.0 20.9 63.2 14.6 64.8 30.5 20.0 62.2 84.6 22.2 61.2 28.7 15.3 24.5 24.0 17.7 22.6 21.3 19.6 64.5 57.7 23.8 15.5 19.7 19.4 55.7 55.9 29.2 32.5 12.6 49.7 18.3 55.3 25.1 14.8 52.9 23.2 17.3 34.8 23.0 21.7 20.2 51.0 20.6 24.2 34.5 57.1 21.0 30.2 21.2 17.4 22.7 19.1 64.9 15.9 27.6 29.0 37.8 30.5 25.2 23.7 13.8 19.9 21.8 31.1 18.5 28.2 22.3 8.4 20.3 31.4 20.9 32.4 18.1 12.4 26.5 30.6 31.7 55.0 0.2 25.4 16.7 30.1 32.6 43.5 20.1 55.2 33.7 14.6 35.6 16.6 24.3 17.5 28.4 14.4 28.7 14.2 13.2 0.0 26.7 20.8 17.2 19.9 30.4 81.4 43.1 22.6 17.8 37.0 38.2 22.8 18.8 14.0 26.7 24.7 35.7 20.7 27.9 27.7 23.2 19.1 31.4 19.1 1.1 3.6 8.2 2.3 3.1 1.6 2.4 1.7 2.5 2.6 2.3 2.6 2.0 3.6 3.0 3.5 2.2 2.9 2.1 63.2 64.8 62.2 84.6 64.5 57.7 55.7 55.9 55.3 51.0 57.1 64.9 11.5 22.4 21.2 54.9 15.3 14.4 9.6 6.9 31.3 16.4 13.0 13.7 20.9 2.8 12.9 9.2 20.9 7.3 12.0 8.0 7.9 9.7 61.4 8.0 10.3 11.1 17.4 4.6 19.7 12.7 5.3 13.9 21.4 10.0 15.8 17.3 6.4 6.1 8.9 18.5 20.5 6.5 6.1 14.8 11.1 178.1 12.5 14.0 16.0 20.6 9.3 8.8 6.2 27.2 54.6 9.2 9.0 9.8 12.3 9.0 17.7 12.3 5.8 15.5 6.6 13.7 12.5 44.3 12.6 19.3 15.8 6.4 13.3 8.6 7.5 9.3 PARP8 "ARTD16, FLJ21308, pART16" ENSG00000151883 "Poly(ADP-ribose) polymerase family member 8" Q8N3A8 5 50665899-50846519 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 78.2" "Cell type enhanced" "Detected in many" "dendritic cells: 124.9;Excitatory neurons: 197.9;Inhibitory neurons: 139.3;Microglial cells: 112.4;Oligodendrocyte precursor cells: 158.3;T-cells: 157.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "THP-1: 91.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049183 Approved Approved "Nucleoplasm,Midbody ring,Cytosol" Yes No "Cluster 16: MAIT-cells - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Midbody ring, Cytosol" "HPA049183: AB_2680667" "unprognostic (1.22e-2)" "unprognostic (2.53e-1)" "unprognostic (1.77e-1)" "unprognostic (1.05e-1)" "unprognostic (2.12e-1)" "unprognostic (6.33e-2)" "unprognostic (8.86e-3)" "unprognostic (7.27e-2)" "unprognostic (1.86e-2)" "unprognostic (8.96e-2)" "unprognostic (2.85e-1)" "unprognostic (6.81e-2)" "unprognostic (9.63e-2)" "unprognostic (2.84e-2)" "unprognostic (4.42e-2)" "unprognostic (4.23e-2)" "prognostic favorable (1.12e-4)" 11.7 13.1 4.6 26.8 8.8 78.2 9.2 0.0 7.9 8.3 0.3 8.8 14.5 6.6 4.2 7.7 9.9 25.7 6.9 14.7 12.6 7.0 8.0 19.8 42.0 3.4 4.5 11.6 12.2 13.8 4.9 12.4 0.1 11.3 9.3 4.6 10.3 7.4 4.8 7.6 15.0 8.4 2.7 43.6 20.2 9.1 7.7 19.2 43.1 2.1 22.5 14.5 5.4 2.0 24.8 0.1 12.2 18.8 3.2 5.7 18.0 4.3 15.7 4.1 12.0 0.9 33.5 14.8 16.9 0.5 43.3 12.4 2.1 13.1 10.0 20.2 15.9 10.6 9.2 1.1 6.3 28.1 0.2 6.8 10.9 8.5 6.0 24.6 0.2 23.1 1.6 9.1 5.9 8.8 31.8 32.5 12.3 0.4 6.0 15.4 24.0 17.1 7.6 12.8 13.0 19.0 13.8 21.6 3.7 17.6 1.0 91.2 0.0 1.0 15.4 1.2 12.6 6.9 0.2 29.5 13.8 7.6 17.7 27.4 13.7 31.9 43.6 4.0 70.6 13.4 34.3 50.5 9.2 16.7 20.9 34.9 28.6 39.5 2.9 4.2 22.5 22.7 4.6 8.8 0.0 7.9 14.7 12.6 3.4 4.5 0.1 2.7 7.7 2.0 6.2 32.1 21.1 29.4 51.7 8.0 5.2 12.7 26.2 13.6 10.4 6.5 5.6 14.3 19.1 22.0 0.0 22.5 124.9 17.2 7.9 14.2 28.7 11.8 8.4 3.9 15.0 7.4 197.9 10.2 6.4 13.4 46.9 10.6 14.5 12.6 6.8 5.0 14.3 6.7 139.3 4.2 8.2 26.1 16.9 15.3 1.2 27.1 8.8 112.4 43.4 0.7 93.7 158.3 7.3 18.7 8.4 3.0 65.0 7.7 8.2 4.3 25.6 2.1 6.6 12.3 13.0 12.8 6.0 14.3 4.0 24.8 157.3 6.5 9.6 13.7 PC PCB ENSG00000173599 "Pyruvate carboxylase" P11498 11 66848417-66958386 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Gluconeogenesis, Lipid biosynthesis, Lipid metabolism" "Ligase, Multifunctional enzyme" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 148.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 201.9;Late spermatids: 53.2" "Cancer enhanced" "Detected in all" "liver cancer: 37.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HeLa: 57.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033742, HPA043922, HPA058765" Enhanced Enhanced Mitochondria Yes No 200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 15: Hepatocytes - Hemostasis" Mitochondria "CAB033742: AB_2283532, HPA043922: AB_2678732, HPA058765: AB_2683812" "unprognostic (2.10e-1)" "unprognostic (1.51e-1)" "unprognostic (1.36e-2)" "unprognostic (8.24e-3)" "unprognostic (3.67e-1)" "unprognostic (3.18e-2)" "unprognostic (2.97e-1)" "unprognostic (3.00e-1)" "unprognostic (3.63e-1)" "prognostic unfavorable (7.86e-5)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "prognostic favorable (8.22e-5)" "unprognostic (8.58e-3)" "unprognostic (5.67e-2)" "unprognostic (9.15e-3)" "unprognostic (1.05e-1)" 60.9 23.7 35.7 2.9 35.5 3.5 28.4 36.6 35.8 3.7 17.5 4.7 6.5 3.8 1.8 9.3 3.2 2.8 4.3 32.4 41.0 23.3 148.0 2.6 1.3 43.4 40.1 5.1 4.9 18.2 8.6 4.4 37.6 7.2 2.8 2.4 35.3 9.3 12.1 4.7 7.7 1.4 37.8 1.5 9.1 10.7 49.0 2.0 4.6 6.6 2.0 2.9 4.4 37.0 6.1 19.3 6.5 17.2 25.4 8.9 6.6 3.4 15.5 6.9 7.5 8.8 6.0 0.0 7.4 6.0 9.6 6.8 7.7 39.5 1.5 2.8 11.0 10.3 57.4 41.2 21.0 0.1 10.8 40.2 10.1 5.8 12.4 4.4 5.7 14.3 17.4 0.0 2.1 44.6 9.2 4.6 12.0 15.1 16.2 8.3 13.0 3.2 5.7 1.9 15.2 21.0 33.6 18.0 15.5 4.8 14.6 2.7 6.3 7.8 6.6 8.8 4.7 3.5 4.8 0.1 7.7 5.7 6.7 0.0 1.3 0.0 0.5 0.3 0.5 0.0 0.1 0.5 0.9 0.2 0.9 0.5 0.1 0.1 0.1 0.3 0.5 0.7 35.7 35.5 36.6 35.8 32.4 41.0 43.4 40.1 37.6 37.8 49.0 37.0 0.9 0.0 3.0 26.4 1.4 1.3 1.6 9.1 2.8 5.6 4.8 5.8 4.4 11.5 3.0 3.7 2.1 17.4 0.6 27.6 1.9 3.1 18.4 2.3 7.1 1.5 9.0 28.0 18.5 1.8 4.2 3.2 5.6 3.0 8.9 16.0 4.6 201.9 12.3 0.0 18.6 5.0 0.0 7.0 1.8 53.2 0.6 1.8 5.4 7.5 18.9 9.4 2.1 10.1 16.7 2.3 8.5 4.1 0.1 3.1 23.6 39.0 1.5 4.8 0.0 2.2 2.2 11.2 4.7 4.1 0.6 25.4 1.2 6.0 6.4 1.3 PCDH20 "FLJ22218, PCDH13" ENSG00000280165 "Protocadherin 20" Q8N6Y1 13 61409685-61415522 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.0;smooth muscle: 9.0" "Cell type enhanced" "Detected in some" "Club cells: 6.2;Excitatory neurons: 8.2;Inhibitory neurons: 7.9;Intestinal goblet cells: 5.3;Ionocytes: 6.1;Oligodendrocyte precursor cells: 32.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 14 "RPTEC TERT1: 51.3" HPA062669 Approved "Vesicles,Cytokinetic bridge" Yes NA "Cluster 10: Brain - Neuronal signaling" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 68: Oligodendrocytes - Mixed function" Vesicles "Cytokinetic bridge" "HPA062669: AB_2732687" "unprognostic (2.40e-1)" "unprognostic (1.80e-1)" "unprognostic (2.45e-1)" "unprognostic (7.83e-2)" "unprognostic (6.79e-4)" "unprognostic (2.32e-2)" "unprognostic (1.56e-1)" "unprognostic (5.34e-4)" "unprognostic (6.96e-2)" "unprognostic (1.67e-1)" "unprognostic (3.12e-1)" 0.5 1.1 3.0 0.3 4.4 0.0 0.9 1.0 11.2 2.3 0.0 3.1 0.9 3.1 2.6 0.7 0.5 0.6 3.5 18.0 3.7 0.8 1.3 3.3 0.0 1.5 4.6 0.3 0.1 0.0 0.5 0.4 1.3 1.0 1.7 0.0 0.7 1.0 0.4 1.0 1.0 9.0 2.3 1.2 1.0 0.1 2.8 0.8 0.2 0.7 0.0 0.6 0.5 2.3 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 51.3 0.0 0.7 1.9 0.0 3.6 0.5 0.1 1.0 0.1 0.0 0.0 0.0 0.0 0.4 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 4.4 1.0 11.2 18.0 3.7 1.5 4.6 1.3 2.3 2.8 2.3 0.0 3.2 0.5 2.3 0.0 0.1 0.1 3.6 0.0 0.0 0.0 0.0 0.6 0.0 6.2 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 8.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 7.9 5.3 6.1 0.0 0.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 32.6 1.0 0.1 2.3 0.0 0.0 0.1 0.0 0.0 2.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.2 PCDHGB1 PCDH-GAMMA-B1 ENSG00000254221 "Protocadherin gamma subfamily B, 1" Q9Y5G3 5 141350102-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.5" "Cell type enhanced" "Detected in some" "Early spermatids: 5.7;Late spermatids: 7.6;Melanocytes: 1.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 12.9;ASC TERT1: 6.6;hTERT-RPE1: 7.1;T-47d: 8.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA076182" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Focal adhesion sites,Midbody" Yes No "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 34: Spermatids - Unknown function" "Vesicles, Plasma membrane" "Nucleoplasm, Focal adhesion sites, Midbody" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA076182: AB_2686783" "unprognostic (1.53e-2)" "unprognostic (1.94e-3)" "unprognostic (3.21e-1)" "unprognostic (4.38e-3)" "unprognostic (2.98e-1)" "unprognostic (8.36e-3)" "unprognostic (2.37e-1)" "unprognostic (9.57e-2)" "unprognostic (8.57e-2)" "unprognostic (1.06e-1)" "unprognostic (3.44e-2)" "unprognostic (4.78e-2)" "unprognostic (6.33e-2)" "unprognostic (3.15e-2)" "unprognostic (8.75e-2)" "unprognostic (1.93e-1)" "unprognostic (7.63e-3)" 0.6 0.7 1.8 0.1 1.2 0.0 0.5 2.1 1.6 0.6 0.0 0.3 0.0 1.2 0.4 0.3 0.4 0.5 0.5 2.9 1.6 0.4 0.1 0.6 0.0 1.9 3.3 1.4 0.8 2.3 1.0 0.2 2.4 0.6 0.1 1.6 0.3 0.9 0.2 0.2 0.1 0.9 2.4 0.1 0.1 0.4 1.8 0.0 0.6 0.3 0.0 0.3 0.3 3.5 0.1 1.9 1.6 0.0 12.9 6.6 0.1 1.2 3.2 0.5 0.7 0.2 0.5 0.5 4.2 0.5 3.1 0.6 0.3 0.2 0.4 0.0 0.8 0.0 0.2 1.2 0.2 0.0 0.0 1.0 0.0 0.0 0.0 7.1 0.1 0.0 0.2 0.2 3.0 1.7 0.4 0.3 0.2 0.0 0.0 0.0 2.4 0.1 0.0 0.0 1.0 0.7 0.0 0.8 0.1 1.2 8.6 0.0 1.0 0.2 1.3 1.1 0.0 0.0 2.4 0.3 2.5 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.2 2.1 1.6 2.9 1.6 1.9 3.3 2.4 2.4 1.8 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.7 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 1.8 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 PCIF1 "bA465L10.1, C20orf67, CAPAM, PPP1R121" ENSG00000100982 "Phosphorylated CTD interacting factor 1" Q9H4Z3 20 45934683-45948023 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049517 Enhanced Supported "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes No "Cluster 5: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 39: CACO-2 - Unknown function" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Microtubules, Cytokinetic bridge" "HPA049517: AB_2680801" "unprognostic (5.42e-3)" "unprognostic (7.76e-2)" "unprognostic (7.69e-2)" "prognostic unfavorable (8.86e-4)" "unprognostic (1.39e-2)" "unprognostic (4.20e-2)" "unprognostic (1.89e-2)" "unprognostic (2.11e-1)" "unprognostic (1.90e-1)" "unprognostic (1.72e-1)" "unprognostic (7.57e-2)" "unprognostic (1.29e-1)" "prognostic favorable (1.50e-6)" "unprognostic (1.01e-1)" "unprognostic (4.44e-2)" "unprognostic (9.14e-3)" "unprognostic (1.24e-1)" 28.7 28.0 20.7 18.6 23.0 33.9 28.7 30.2 24.2 36.1 17.6 30.7 16.5 39.7 10.8 24.4 35.3 16.3 31.9 20.4 20.2 23.4 19.5 28.2 27.3 22.7 21.6 41.7 29.5 22.8 26.0 17.0 22.1 26.2 11.7 15.9 23.6 21.3 41.7 36.7 27.2 21.3 20.9 34.7 25.4 18.1 21.7 34.4 32.0 27.6 19.6 28.6 29.3 24.9 21.2 29.0 22.0 27.2 15.3 18.2 24.2 8.3 25.1 24.9 24.2 49.3 27.7 22.7 27.4 22.6 28.7 23.4 15.8 29.0 10.8 14.1 11.4 29.1 23.1 33.4 28.2 26.4 28.1 25.5 29.9 15.3 24.5 22.3 21.0 37.1 20.8 30.9 17.9 44.6 52.3 48.3 7.8 25.5 24.9 32.2 20.4 28.0 20.1 21.8 30.2 30.0 31.5 29.5 16.1 11.6 31.0 30.7 18.1 30.7 24.1 27.3 16.8 35.4 22.1 21.0 37.7 23.8 18.2 75.5 47.5 80.2 54.5 47.2 43.0 51.6 47.3 50.2 50.3 56.2 48.6 43.0 74.6 74.3 48.0 40.4 54.4 64.0 20.7 23.0 30.2 24.2 20.4 20.2 22.7 21.6 22.1 20.9 21.7 24.9 19.7 3.2 14.2 4.6 33.7 8.7 26.4 7.9 26.2 9.9 17.0 19.7 21.9 20.0 7.1 11.0 2.1 19.5 32.4 14.6 15.6 21.4 9.6 13.3 10.7 16.1 26.5 25.4 2.5 38.6 22.6 15.4 17.3 13.5 14.5 14.9 9.7 12.4 16.9 13.5 3.6 14.0 4.1 16.0 8.7 8.1 11.5 21.5 17.8 1.0 24.9 12.0 33.0 3.0 3.9 28.3 13.1 12.8 35.5 25.4 14.8 23.2 11.0 13.4 0.0 20.2 19.3 14.4 11.9 23.8 10.7 27.8 30.8 15.1 12.0 38.8 PCP2 "GPSM4, MGC41903" ENSG00000174788 "Purkinje cell protein 2" Q8IVA1 19 7631611-7633719 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 53.4;retina: 33.3;testis: 112.4" "Cell type enriched" "Detected in many" 4 "Late spermatids: 4139.3" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "cerebellum: 53.4;white matter: 16.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 8.4;Karpas-707: 4.2;NB-4: 17.7" "Region enriched" "Detected in many" 44 "cerebellum: 2160.4" "Region enriched" "Detected in all" 28 "cerebellum: 552.9" HPA057428 Approved "Nuclear speckles,Vesicles" Yes NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear speckles" Vesicles "HPA057428: AB_2683436" "prognostic favorable (7.93e-4)" "unprognostic (6.06e-2)" "unprognostic (1.19e-2)" "unprognostic (4.43e-2)" "unprognostic (1.49e-1)" "unprognostic (1.79e-4)" "unprognostic (1.19e-1)" "unprognostic (4.88e-5)" "unprognostic (1.11e-1)" "unprognostic (6.23e-2)" "unprognostic (9.15e-3)" "unprognostic (6.01e-2)" "unprognostic (1.36e-2)" "unprognostic (8.17e-2)" "unprognostic (1.18e-1)" "unprognostic (8.70e-2)" "prognostic favorable (2.76e-5)" 0.4 1.6 0.4 1.1 0.6 3.7 5.5 53.4 2.3 2.1 0.0 0.6 1.4 0.9 3.3 2.0 2.4 2.3 2.2 0.5 0.0 8.0 3.7 2.2 3.0 0.1 3.5 0.1 5.4 1.1 1.4 0.4 5.5 5.9 0.3 33.3 16.3 1.9 0.2 7.0 1.6 0.0 0.1 3.0 3.1 112.4 0.0 3.1 5.7 0.0 1.4 0.9 1.6 16.8 1.8 0.4 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.7 1.6 0.7 1.1 0.0 0.0 1.3 0.0 0.2 0.0 0.8 0.6 2.6 2.8 0.1 0.0 0.3 8.4 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.2 4.2 0.0 0.3 0.3 17.7 0.4 0.3 0.0 0.8 0.2 0.7 0.8 0.1 0.1 0.0 1.4 1.4 0.0 0.4 3.7 3.4 0.2 0.0 0.5 0.4 0.0 1.4 0.7 0.2 0.0 2.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.1 0.1 0.1 0.2 0.3 0.2 0.3 0.8 0.2 0.0 0.6 0.0 1.7 0.4 0.6 53.4 2.3 0.5 0.0 0.1 3.5 5.5 0.1 0.0 16.8 0.1 0.0 2.3 0.0 0.2 0.8 1.1 1.4 0.0 734.7 7.7 5.8 0.0 2.8 1.8 5.5 22.9 0.2 2.7 0.7 9.8 0.8 836.5 1.0 0.1 2.6 0.0 0.0 0.0 0.2 0.1 0.1 0.0 1.5 1.3 1.3 0.0 0.5 0.4 23.5 0.0 0.4 0.0 0.8 1.3 4139.3 10.5 7.1 1.8 1.0 1.5 40.7 2.1 0.0 0.0 0.4 0.1 13.2 0.3 1.0 1.3 0.5 0.4 100.3 19.7 0.0 0.1 14.5 9.0 0.0 1.1 0.0 1.0 0.0 0.6 0.6 PDCD2 "RP8, ZMYND7" ENSG00000071994 "Programmed cell death 2" Q16342 6 170575295-170584692 "Predicted intracellular proteins" Apoptosis DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026713, HPA075534" Approved Approved "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 32: Non-specific - Translation" Nucleoplasm "Cytokinetic bridge" "HPA026713: AB_1855103, HPA075534: AB_2686754" "unprognostic (3.80e-3)" "unprognostic (1.90e-2)" "unprognostic (1.37e-2)" "unprognostic (4.61e-2)" "unprognostic (5.83e-2)" "unprognostic (8.91e-3)" "prognostic unfavorable (1.42e-6)" "unprognostic (9.91e-2)" "unprognostic (7.75e-2)" "unprognostic (1.25e-2)" "unprognostic (3.17e-2)" "unprognostic (3.85e-2)" "unprognostic (4.45e-3)" "unprognostic (9.16e-2)" "unprognostic (1.66e-1)" "unprognostic (2.00e-1)" "unprognostic (1.09e-1)" 26.3 25.6 18.9 30.0 19.1 35.4 43.0 20.2 23.7 27.1 18.4 31.1 32.4 25.9 39.9 32.6 33.7 23.4 22.8 19.3 20.2 33.2 32.7 23.4 43.2 19.2 20.0 29.8 45.4 29.6 16.9 28.4 19.3 25.9 38.4 17.7 31.7 30.3 36.4 25.8 25.9 28.7 19.0 27.5 30.6 19.9 19.5 42.3 34.6 27.0 50.6 32.8 21.6 19.3 50.5 36.2 53.8 126.7 75.8 82.6 59.3 58.6 66.7 67.9 75.3 65.2 43.1 90.6 46.6 64.8 90.8 70.5 116.5 97.1 98.9 74.7 127.2 128.6 46.2 119.3 91.9 161.6 83.3 75.6 93.4 86.2 138.7 71.2 95.8 123.9 260.3 57.7 84.1 109.5 113.0 116.6 77.5 161.6 54.9 79.4 41.5 117.8 103.7 29.3 98.4 102.4 66.7 107.8 71.6 58.1 54.8 162.8 73.0 33.3 71.4 80.1 105.1 76.5 96.4 97.9 62.1 154.9 87.0 4.1 12.4 11.5 14.1 12.0 16.5 14.2 15.9 14.9 17.3 13.8 15.5 14.8 5.3 18.8 15.2 15.9 20.3 12.0 18.9 19.1 20.2 23.7 19.3 20.2 19.2 20.0 19.3 19.0 19.5 19.3 47.2 12.8 15.3 9.4 54.1 49.5 76.4 14.6 40.5 36.9 58.0 59.7 27.4 52.9 14.0 29.5 12.5 63.9 82.2 29.2 78.2 55.3 17.0 36.1 38.5 38.8 47.2 64.1 13.2 74.1 71.6 32.2 32.1 33.5 15.9 59.8 44.6 28.2 49.2 16.8 12.7 44.0 22.4 41.9 33.2 15.0 49.0 40.9 35.6 8.4 62.8 34.7 84.5 8.0 12.4 58.6 36.4 40.6 58.0 103.9 47.8 83.6 16.0 35.3 19.7 43.8 55.5 33.0 85.8 58.7 46.0 46.7 60.7 60.8 68.0 84.1 PDE4C DPDE1 ENSG00000105650 "Phosphodiesterase 4C" Q08493 19 18208652-18248200 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 21.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 255.9;Gastric mucus-secreting cells: 141.2;Paneth cells: 251.4;Proximal enterocytes: 73.0;Skeletal myocytes: 106.5;Undifferentiated cells: 103.3" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "basal ganglia: 1.2;cerebral cortex: 1.1" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.0" "Cell line enhanced" "Detected in some" "BEWO: 2.9;Hep G2: 2.0;U-87 MG: 4.4" "HPA048975, HPA054218" Approved Approved "Midbody ring,Centrosome,Cytosol" Yes NA "Cluster 17: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Centrosome, Cytosol" "Midbody ring" "HPA048975: AB_2680581, HPA054218: " "unprognostic (4.20e-2)" "unprognostic (4.02e-2)" "unprognostic (1.20e-1)" "unprognostic (1.27e-1)" "unprognostic (5.22e-4)" "unprognostic (1.44e-2)" "unprognostic (7.70e-2)" "unprognostic (1.15e-1)" "unprognostic (4.01e-2)" "unprognostic (5.69e-2)" "unprognostic (2.50e-3)" "unprognostic (2.21e-1)" "unprognostic (7.25e-10)" "unprognostic (2.73e-2)" "unprognostic (2.65e-1)" "unprognostic (9.21e-2)" "unprognostic (2.45e-2)" 1.4 0.6 0.2 0.1 1.2 0.5 0.7 0.0 1.1 3.2 0.0 4.3 0.7 3.4 3.4 0.7 3.0 1.1 4.4 0.2 0.0 4.8 1.3 3.4 0.2 0.0 0.0 1.8 0.7 0.2 2.8 3.7 0.0 2.3 0.6 0.2 0.5 2.7 8.3 0.3 2.4 1.8 0.0 2.1 3.8 2.5 0.0 0.0 1.1 21.3 0.1 1.0 1.7 0.0 0.0 0.1 0.0 0.1 0.0 0.1 2.9 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 2.0 0.1 0.0 0.2 0.3 0.0 1.2 0.0 0.2 0.0 0.1 0.4 0.9 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.2 0.0 0.0 0.1 0.4 0.1 0.2 0.0 0.7 0.2 0.2 0.0 0.1 0.0 0.3 0.0 0.6 0.3 0.1 4.4 0.1 0.0 1.0 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.7 0.2 0.1 0.1 0.0 0.0 0.2 1.2 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 3.2 10.6 2.0 0.8 5.5 5.8 8.6 5.2 3.9 0.2 0.4 35.3 4.3 22.4 0.0 6.2 2.1 0.0 255.9 0.0 0.0 32.9 0.1 0.1 4.6 7.2 0.0 8.2 0.0 4.3 6.3 141.2 0.1 4.5 0.0 1.1 0.3 0.5 0.0 2.1 55.2 4.1 1.4 4.5 38.4 0.6 2.1 1.8 0.0 0.4 1.9 1.0 0.5 0.9 0.0 251.4 4.1 1.6 1.8 73.0 0.0 9.4 3.0 46.0 106.5 17.2 1.9 2.2 28.6 3.8 1.1 1.2 0.0 103.3 17.3 PDP1 "PDH, PDP, PPM2A, PPM2C" ENSG00000164951 "Pyruvate dehyrogenase phosphatase catalytic subunit 1" Q9P0J1 8 93857807-93926068 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 80.0;Early spermatids: 144.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 8 "amygdala: 14.2;basal ganglia: 20.1;cerebral cortex: 41.7;hippocampal formation: 23.4;white matter: 18.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 117.8;hTERT-RPE1: 117.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018483, HPA019081, HPA021152" Uncertain Approved Nucleoplasm,Mitochondria,Cytosol Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria, Cytosol" "HPA018483: AB_1855634, HPA019081: AB_1855633, HPA021152: AB_1855635" "prognostic unfavorable (8.61e-5)" "unprognostic (4.62e-1)" "unprognostic (8.79e-2)" "unprognostic (1.09e-1)" "unprognostic (9.46e-2)" "unprognostic (1.38e-1)" "unprognostic (1.59e-1)" "unprognostic (1.18e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.71e-2)" "unprognostic (3.25e-1)" "prognostic favorable (8.42e-9)" "unprognostic (1.85e-1)" "unprognostic (1.84e-1)" "unprognostic (5.04e-2)" "unprognostic (1.67e-1)" 10.6 62.6 14.2 10.5 20.1 14.4 16.1 0.0 41.7 14.2 1.2 8.9 7.2 15.5 17.0 14.2 12.2 19.4 49.2 23.4 0.0 12.8 4.2 12.6 12.9 0.0 2.3 19.3 19.9 29.9 5.4 13.8 0.0 10.3 12.4 14.1 11.7 9.4 72.9 4.3 7.6 11.2 0.0 13.2 11.7 26.7 3.0 11.6 18.8 16.9 12.4 14.0 6.8 18.5 25.7 12.0 25.9 10.9 21.0 37.9 8.6 19.3 21.7 22.1 25.8 12.7 90.3 13.9 63.8 30.8 117.8 54.4 11.0 16.1 32.8 1.5 5.6 6.6 15.7 4.5 23.9 3.3 9.0 24.5 31.5 37.7 59.8 117.1 50.9 12.4 2.4 22.8 27.6 6.0 20.3 10.3 12.1 26.8 15.4 4.8 15.5 2.6 15.3 17.0 2.4 11.4 12.7 1.4 61.8 20.9 4.0 3.9 90.9 27.5 17.2 63.8 23.3 12.6 5.8 12.1 34.2 11.7 25.1 6.4 27.9 14.5 9.2 25.3 8.9 15.6 15.1 12.0 22.5 17.9 8.9 7.8 3.1 5.4 41.1 3.7 34.9 18.0 14.2 20.1 0.0 41.7 23.4 0.0 0.0 2.3 0.0 0.0 3.0 18.5 10.7 12.8 7.8 15.0 18.0 13.0 12.7 36.3 68.9 38.3 11.6 7.0 80.0 14.3 35.6 16.5 8.4 4.3 13.7 27.5 5.9 33.3 144.2 33.3 14.9 15.0 10.2 1.3 73.6 14.0 3.9 20.8 16.3 70.2 6.3 3.7 12.5 3.3 6.3 10.1 23.4 5.5 10.2 19.2 19.1 28.1 11.5 19.9 10.6 19.7 22.4 18.8 10.3 13.0 8.5 24.5 9.6 13.5 8.1 15.6 4.9 11.4 30.5 11.5 6.6 35.4 13.1 10.1 11.4 26.5 10.9 4.4 19.3 7.1 10.7 23.9 PES1 "NOP7, PES" ENSG00000100029 "Pescadillo ribosomal biogenesis factor 1" O00541 22 30576625-30607083 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040210, HPA062439, HPA066670" Supported Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA040210: AB_2676885, HPA062439: AB_2684764, HPA066670: AB_2685700" "unprognostic (1.82e-1)" "unprognostic (5.88e-2)" "unprognostic (5.59e-3)" "unprognostic (4.83e-2)" "unprognostic (1.48e-1)" "unprognostic (3.23e-3)" "prognostic unfavorable (1.84e-9)" "unprognostic (3.29e-2)" "unprognostic (3.40e-1)" "unprognostic (1.73e-1)" "unprognostic (4.79e-2)" "unprognostic (2.46e-2)" "unprognostic (5.65e-2)" "unprognostic (1.27e-3)" "unprognostic (1.65e-1)" "unprognostic (4.56e-2)" "unprognostic (1.42e-1)" 33.3 41.0 26.3 29.2 28.6 35.5 32.2 26.7 30.5 31.8 27.1 29.6 21.7 35.5 21.2 43.6 29.4 20.2 28.8 26.9 26.2 38.7 48.2 26.2 32.3 27.1 27.2 34.2 57.3 30.1 21.8 21.5 27.6 32.9 19.6 9.2 29.3 21.5 48.8 45.3 28.2 22.5 25.8 34.4 35.7 40.0 27.0 23.8 27.1 20.0 27.3 35.0 31.9 30.0 132.2 146.6 53.0 113.7 59.9 58.4 81.6 84.7 69.6 141.6 110.0 170.6 55.2 177.2 74.4 97.0 110.3 89.4 163.9 153.5 103.1 76.4 159.8 85.9 80.8 149.0 149.3 209.6 86.8 82.7 94.7 148.3 147.3 68.3 93.0 62.4 144.6 69.9 87.7 164.3 102.6 209.8 103.1 128.3 106.7 129.0 91.7 173.3 78.9 88.7 91.4 94.6 84.2 94.6 117.8 42.0 66.8 106.1 74.2 165.9 126.1 85.3 145.1 88.1 81.0 178.6 116.2 94.9 109.0 7.5 24.9 6.4 18.9 29.8 23.2 20.2 17.4 18.1 26.8 20.0 19.4 18.0 0.9 20.0 22.3 23.2 14.3 29.3 26.3 28.6 26.7 30.5 26.9 26.2 27.1 27.2 27.6 25.8 27.0 30.0 23.6 3.2 18.9 4.9 17.4 22.6 23.4 32.7 22.2 6.5 14.1 12.2 3.8 24.3 22.1 25.8 8.4 34.9 7.8 19.6 25.4 48.0 44.4 11.7 13.8 23.2 23.4 24.6 4.3 43.9 40.0 15.4 22.4 10.6 18.3 24.4 27.8 22.8 38.4 3.3 4.3 22.4 22.4 27.8 12.6 14.3 19.9 21.2 21.4 2.8 29.0 13.5 16.5 6.6 5.1 38.7 16.2 20.3 28.3 26.4 31.3 55.1 24.6 8.9 19.7 23.2 20.7 28.7 20.9 25.9 22.9 28.5 13.5 19.9 29.7 15.1 PGAP6 "M83, TMEM6, TMEM8, TMEM8A" ENSG00000129925 "Post-glycosylphosphatidylinositol attachment to proteins 6" Q9HCN3 16 370788-387113 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 63.7;Hofbauer cells: 29.2;Syncytiotrophoblasts: 100.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 36.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 129.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA051281, HPA064673" Approved Supported "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Cytokinetic bridge" "HPA051281: AB_2681418, HPA064673: AB_2685317" "unprognostic (5.84e-2)" "unprognostic (6.13e-2)" "unprognostic (3.85e-2)" "unprognostic (3.21e-2)" "unprognostic (5.77e-2)" "unprognostic (3.19e-2)" "unprognostic (1.13e-3)" "unprognostic (1.56e-2)" "unprognostic (8.89e-2)" "unprognostic (7.73e-2)" "unprognostic (3.43e-1)" "unprognostic (1.38e-2)" "prognostic favorable (1.29e-5)" "unprognostic (4.20e-3)" "unprognostic (3.19e-2)" "unprognostic (4.93e-2)" "unprognostic (2.48e-1)" 23.5 25.5 13.5 18.0 15.1 30.0 20.1 11.8 17.7 17.7 14.5 39.6 31.4 19.2 24.8 31.9 17.7 16.4 37.7 12.8 11.0 59.4 57.6 36.2 17.0 14.6 12.6 12.2 102.8 19.3 28.8 34.8 13.5 30.3 10.3 5.6 40.8 12.5 36.1 11.3 38.5 8.8 11.9 36.0 53.9 63.3 16.0 11.7 28.0 10.1 7.9 23.4 14.3 14.6 12.7 32.8 18.4 33.9 24.7 22.1 36.7 35.5 36.6 17.7 25.3 129.2 57.9 13.4 47.1 34.5 27.3 17.8 8.4 39.2 4.9 38.5 31.1 22.1 23.1 74.8 56.9 16.9 40.4 25.7 11.6 27.4 7.9 18.0 41.4 14.8 36.2 20.1 22.6 78.2 23.9 33.2 29.2 20.1 12.9 51.0 21.0 31.2 28.8 32.0 21.9 25.2 19.8 19.7 106.3 9.6 35.7 33.4 61.1 50.2 53.6 35.2 19.2 40.3 21.6 27.0 25.5 17.8 32.5 7.1 7.6 10.1 10.7 8.6 8.3 2.5 8.1 8.3 3.9 2.6 10.7 8.0 36.0 1.5 6.1 4.2 6.6 5.7 13.5 15.1 11.8 17.7 12.8 11.0 14.6 12.6 13.5 11.9 16.0 14.6 11.7 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 63.7 8.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 7.4 2.9 0.0 0.0 0.0 0.0 0.0 0.0 29.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 100.2 1.4 0.0 0.0 0.0 PHLPP2 "KIAA0931, PHLPPL, PPM3B" ENSG00000040199 "PH domain and leucine rich repeat protein phosphatase 2" Q6ZVD8 16 71637835-71724701 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.0;retina: 32.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 104.3;Distal enterocytes: 75.5;Excitatory neurons: 69.5;Proximal enterocytes: 73.7;Rod photoreceptor cells: 68.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040761, HPA041837, HPA048598" Approved Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 45: Enterocytes - Digestion" Cytosol "Nucleoplasm, Cytokinetic bridge, Mitotic spindle" "HPA040761: , HPA041837: , HPA048598: AB_2680459" "unprognostic (5.67e-2)" "unprognostic (2.00e-1)" "unprognostic (2.29e-2)" "unprognostic (2.44e-2)" "unprognostic (1.76e-1)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" "unprognostic (3.27e-1)" "unprognostic (1.22e-1)" "unprognostic (3.43e-1)" "unprognostic (1.97e-4)" "unprognostic (3.08e-2)" "unprognostic (8.85e-3)" "unprognostic (6.41e-2)" "unprognostic (4.92e-2)" "unprognostic (8.46e-3)" "unprognostic (8.27e-2)" 4.2 2.8 6.6 2.8 7.5 6.5 2.7 5.8 7.4 3.5 0.1 11.7 11.1 3.7 2.9 1.4 3.2 2.4 2.8 7.8 4.8 3.4 3.0 3.1 3.5 4.6 3.9 4.2 3.1 4.5 4.0 2.7 4.7 2.7 12.2 32.2 1.7 3.4 1.9 1.8 22.0 4.5 0.6 2.5 2.4 6.8 5.3 1.9 6.6 2.6 3.2 3.3 2.4 5.1 6.0 7.8 8.3 9.3 6.5 7.8 4.8 8.8 8.0 12.5 10.1 7.2 1.9 11.8 3.4 14.6 9.0 12.4 12.1 4.5 16.1 4.2 6.5 3.3 7.3 4.8 5.1 2.9 5.0 5.8 2.5 17.7 5.7 5.2 4.7 4.1 3.0 3.2 8.7 12.7 3.9 2.3 6.5 1.9 2.1 6.3 7.3 3.9 5.9 4.5 7.2 3.8 18.9 5.1 3.1 6.4 6.3 1.6 6.5 12.5 9.0 5.3 7.4 7.1 5.4 11.9 7.7 2.3 2.8 0.2 0.1 0.0 0.2 0.1 0.2 0.5 0.1 0.3 0.1 0.3 0.2 0.2 0.2 0.7 0.1 0.5 0.3 0.1 6.6 7.5 5.8 7.4 7.8 4.8 4.6 3.9 4.7 0.6 5.3 5.1 4.0 9.6 2.2 26.1 7.4 9.3 5.1 3.5 7.4 20.6 6.9 5.6 3.3 0.0 3.6 3.7 104.3 4.3 3.8 75.5 0.0 2.7 12.0 2.9 6.1 5.3 6.0 22.9 69.5 2.3 0.4 7.7 1.1 5.1 10.2 11.3 2.9 4.1 1.5 23.5 45.9 6.7 4.1 7.0 12.7 6.3 5.3 2.7 14.2 10.3 3.2 6.5 1.0 30.7 32.7 2.5 31.4 5.3 4.0 8.2 73.7 5.1 3.1 68.6 6.6 7.8 7.9 31.6 20.4 1.9 9.1 1.4 4.9 1.7 9.2 2.2 PHYKPL "AGXT2L2, MGC15875" ENSG00000175309 "5-phosphohydroxy-L-lysine phospho-lyase" Q8IUZ5 5 178208471-178232802 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036461, HPA063608" Approved Approved Mitochondria Yes No 160000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 34: Non-specific - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA036461: AB_10670717, HPA063608: AB_2685059" "unprognostic (3.29e-3)" "unprognostic (2.60e-1)" "unprognostic (5.51e-2)" "unprognostic (9.75e-2)" "unprognostic (1.28e-1)" "unprognostic (1.47e-1)" "unprognostic (1.24e-1)" "unprognostic (1.06e-2)" "unprognostic (1.68e-2)" "unprognostic (3.29e-1)" "unprognostic (5.38e-2)" "unprognostic (1.02e-3)" "prognostic unfavorable (3.82e-5)" "unprognostic (3.66e-2)" "unprognostic (1.55e-1)" "unprognostic (1.02e-1)" "unprognostic (2.41e-3)" 23.2 10.6 7.4 16.4 8.2 14.9 14.0 6.8 8.6 12.3 8.3 23.9 20.7 14.3 15.8 11.1 13.9 14.4 15.5 6.7 8.3 17.5 42.2 15.8 24.5 11.4 8.3 12.5 15.6 13.7 5.2 16.3 10.0 13.7 30.8 3.4 13.8 12.0 19.6 10.7 24.8 18.5 7.6 17.2 15.5 5.9 9.5 25.1 19.7 18.7 23.6 13.7 9.6 11.7 9.6 3.8 9.0 3.6 21.6 17.4 13.9 5.6 6.2 7.6 11.8 9.7 11.7 13.0 18.4 17.6 9.7 6.2 7.7 14.3 8.5 24.0 8.7 15.6 18.0 7.1 35.1 9.2 11.4 19.6 15.0 9.3 22.4 14.9 24.9 18.6 11.8 26.7 11.3 13.1 13.1 5.5 1.9 11.5 12.4 9.1 4.3 25.0 13.4 8.3 5.7 5.4 9.2 5.2 9.4 10.2 5.5 7.4 9.9 7.8 7.0 5.1 6.2 18.8 5.5 7.2 2.2 9.2 5.2 16.7 41.7 36.9 20.3 46.8 20.4 28.4 22.2 22.9 53.4 26.3 27.3 22.2 9.2 23.7 47.2 70.9 28.6 33.2 7.4 8.2 6.8 8.6 6.7 8.3 11.4 8.3 10.0 7.6 9.5 11.7 23.1 19.2 14.3 31.6 63.0 10.7 43.1 16.1 25.0 21.9 17.2 14.5 17.4 37.1 13.0 23.9 25.0 18.4 72.5 96.1 19.6 24.6 21.7 13.2 27.7 26.2 19.2 30.7 20.7 18.6 20.2 33.4 76.9 13.8 12.7 38.4 31.1 30.1 31.7 15.2 17.9 40.8 6.1 37.1 22.9 55.3 42.6 43.3 24.9 36.5 61.1 25.0 70.0 29.1 45.2 15.1 64.5 25.2 51.4 30.3 119.2 43.1 13.6 26.4 13.1 34.5 23.6 37.2 25.9 14.6 10.4 22.0 58.9 36.3 39.2 36.6 PIAS2 "ARIP3, miz, PIASX-ALPHA, PIASX-BETA, ZMIZ4" ENSG00000078043 "Protein inhibitor of activated STAT 2" O75928 18 46803218-46920160 "Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 67.2" "Cell type enhanced" "Detected in all" "Early spermatids: 521.4;Late spermatids: 519.5;Spermatocytes: 238.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068792 Enhanced Supported Nucleoplasm Yes No "Cluster 26: Non-specific - Mitochondria" "Cluster 78: Testis - Spermatogenesis" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA068792: AB_2686037" "unprognostic (9.59e-3)" "unprognostic (2.14e-1)" "unprognostic (1.63e-1)" "unprognostic (2.75e-2)" "unprognostic (1.25e-1)" "unprognostic (6.39e-2)" "unprognostic (1.05e-3)" "unprognostic (3.67e-2)" "unprognostic (1.05e-1)" "unprognostic (3.71e-3)" "unprognostic (1.77e-3)" "unprognostic (1.02e-1)" "unprognostic (1.23e-1)" "unprognostic (1.58e-1)" "unprognostic (6.92e-2)" "prognostic unfavorable (1.27e-4)" "unprognostic (1.71e-1)" 4.8 5.4 7.3 4.1 8.1 7.4 5.1 16.9 9.8 4.9 6.4 4.9 2.8 5.0 7.5 3.7 4.5 4.6 6.8 8.7 6.2 6.4 5.9 4.3 6.2 4.7 6.9 5.0 4.2 11.8 5.6 3.9 5.4 6.5 7.0 10.9 5.5 4.4 16.1 7.7 4.2 4.7 3.7 6.0 4.5 67.2 7.9 4.6 8.2 10.2 5.2 4.1 4.4 8.0 13.7 5.5 6.1 8.7 6.0 7.5 2.9 7.0 5.6 6.0 5.5 6.5 5.1 13.7 3.7 5.3 6.1 4.5 12.3 7.5 8.5 6.6 4.6 8.5 5.4 7.7 5.9 14.3 5.8 7.7 4.5 5.3 5.6 9.7 5.5 11.9 6.4 3.5 12.0 7.4 8.2 8.3 6.7 2.5 3.5 15.0 13.1 0.1 5.5 10.4 11.7 9.0 6.4 4.1 4.7 6.8 6.1 6.3 6.9 12.8 5.5 4.5 5.3 10.1 5.4 17.7 9.5 15.1 12.8 0.7 1.7 1.2 2.0 1.3 1.3 1.6 1.8 2.4 2.0 3.0 2.5 2.1 1.0 1.9 1.3 2.1 1.9 0.8 7.3 8.1 16.9 9.8 8.7 6.2 4.7 6.9 5.4 3.7 7.9 8.0 26.3 19.2 21.9 60.4 25.0 20.6 19.9 15.2 23.9 57.7 21.8 13.2 30.7 12.8 12.6 25.8 89.6 2.6 32.8 18.1 19.6 13.5 521.4 16.6 25.4 26.0 28.5 16.6 137.9 8.9 2.3 20.6 19.4 15.9 14.5 48.4 34.2 22.3 28.1 32.0 134.9 18.0 16.2 50.3 15.7 519.5 33.5 24.2 12.4 73.1 34.7 21.9 40.2 133.7 94.0 7.9 17.1 35.0 30.3 28.4 11.8 23.1 13.9 36.0 6.6 42.5 18.2 238.7 72.4 24.7 15.3 1.4 19.2 35.6 25.5 18.0 PIGP "DCRC, DSCR5, DSRC" ENSG00000185808 "Phosphatidylinositol glycan anchor biosynthesis class P" P57054 21 37062846-37073170 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 350.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026921 Uncertain Approved Vesicles Yes No "Cluster 30: Non-specific - Translation" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Vesicles "HPA026921: AB_1847874" "unprognostic (4.47e-3)" "unprognostic (9.45e-2)" "unprognostic (3.03e-1)" "unprognostic (2.40e-1)" "unprognostic (2.85e-2)" "unprognostic (1.92e-2)" "unprognostic (1.92e-2)" "unprognostic (5.54e-2)" "unprognostic (1.55e-1)" "unprognostic (1.22e-2)" "unprognostic (4.21e-3)" "unprognostic (1.12e-2)" "unprognostic (1.96e-2)" "unprognostic (1.93e-1)" "unprognostic (5.48e-2)" "unprognostic (1.02e-1)" "unprognostic (6.55e-2)" 33.9 41.3 18.7 12.5 20.2 9.1 35.4 22.4 24.7 22.9 24.8 24.2 19.0 18.3 107.2 16.8 25.7 22.5 40.1 18.1 22.8 35.9 54.7 21.6 16.6 22.8 21.6 27.9 41.4 51.9 38.0 20.9 22.6 33.7 27.4 28.6 32.2 26.7 44.0 12.4 15.5 17.1 22.1 14.9 22.8 36.5 20.0 22.0 36.3 42.8 19.7 26.2 13.2 25.4 25.9 11.5 23.7 14.8 41.5 28.6 16.9 21.9 38.7 18.6 21.1 15.4 53.7 37.1 45.7 32.0 81.4 19.4 22.7 25.5 18.5 37.4 36.1 86.2 13.8 21.3 26.3 26.9 16.6 26.5 47.2 33.4 43.0 42.2 35.1 80.5 50.7 61.8 38.5 16.5 32.9 25.5 19.6 76.8 27.9 31.0 12.1 37.0 48.2 13.3 49.2 29.8 61.4 43.0 81.8 33.6 35.2 53.2 18.3 12.9 6.6 14.8 19.3 81.1 96.5 42.0 38.1 30.5 43.4 0.4 13.5 3.7 19.6 20.3 24.8 34.2 25.1 21.6 20.9 28.1 33.3 29.0 1.9 16.8 22.6 30.9 20.6 15.6 18.7 20.2 22.4 24.7 18.1 22.8 22.8 21.6 22.6 22.1 20.0 25.4 37.4 28.9 41.8 9.8 37.0 33.0 58.9 88.9 35.3 21.2 74.1 86.4 82.4 42.9 65.1 44.1 10.4 60.7 29.4 21.6 90.1 61.8 79.3 67.0 35.9 31.3 44.9 25.7 6.9 71.3 52.4 48.9 30.1 49.3 15.9 32.2 35.3 79.8 66.7 16.8 8.7 63.9 65.1 57.6 39.9 75.6 69.0 44.1 37.4 2.8 50.2 37.0 23.7 7.5 18.2 57.7 50.3 35.0 54.3 45.6 52.3 97.1 86.9 33.6 65.7 32.7 44.6 350.8 177.5 44.2 26.3 52.3 31.7 62.6 53.1 63.7 PIK3CB PIK3C1 ENSG00000051382 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta" P42338 3 138652698-138834928 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Autophagy, Cell adhesion, Endocytosis" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 96.5;Inhibitory neurons: 92.4;Oligodendrocytes: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEL: 115.2;HMC-1: 185.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031938, HPA042288, HPA064207" Approved Supported Nucleoplasm,Nucleoli,Vesicles,Midbody Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nucleoli, Vesicles, Midbody" "CAB031938: AB_2165408, HPA042288: , HPA064207: AB_2685212" "unprognostic (4.89e-2)" "unprognostic (1.42e-2)" "unprognostic (5.97e-2)" "unprognostic (7.85e-2)" "unprognostic (4.89e-2)" "unprognostic (6.01e-2)" "prognostic unfavorable (6.42e-4)" "unprognostic (3.98e-2)" "unprognostic (1.35e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.99e-5)" "unprognostic (2.15e-1)" "unprognostic (6.18e-3)" "unprognostic (9.33e-2)" "unprognostic (7.82e-2)" "unprognostic (2.79e-1)" "unprognostic (4.59e-2)" 11.6 7.4 4.3 12.4 5.0 23.7 11.9 8.6 8.6 12.4 14.4 17.8 17.8 8.2 7.0 18.0 12.1 10.3 15.8 5.4 4.4 26.4 11.0 11.2 12.3 5.1 3.3 9.2 22.3 19.3 2.7 18.6 6.1 15.0 18.1 23.0 19.8 12.0 19.5 23.7 17.9 9.1 3.5 10.8 13.0 8.0 4.0 17.0 43.2 13.2 13.2 9.9 5.4 7.9 64.1 21.9 11.7 9.4 10.6 13.0 79.2 14.2 14.5 15.1 16.7 26.0 25.2 25.0 38.0 13.7 29.1 27.5 15.1 24.1 27.3 31.8 12.5 115.2 14.8 17.3 11.8 30.1 185.1 12.4 17.6 10.2 21.9 26.4 21.5 12.3 43.0 19.0 18.1 28.6 17.8 20.7 16.6 49.2 19.5 11.5 12.2 19.6 24.5 35.5 9.8 7.4 37.6 18.0 56.2 34.7 44.8 73.0 20.3 8.4 11.7 21.2 21.1 30.3 22.1 23.7 22.8 27.7 14.0 4.4 5.1 6.9 2.4 2.8 1.6 2.8 2.8 1.8 5.9 2.6 3.5 2.4 6.4 0.8 2.8 1.0 1.5 2.0 4.3 5.0 8.6 8.6 5.4 4.4 5.1 3.3 6.1 3.5 4.0 7.9 19.7 9.6 21.3 40.1 12.1 19.1 18.7 12.5 14.2 16.2 13.1 7.7 37.3 12.8 18.3 18.4 25.0 35.5 6.9 30.3 5.9 11.1 1.1 18.3 4.0 13.9 16.3 8.0 96.5 19.4 61.1 7.3 21.4 18.8 14.5 6.7 9.7 19.1 14.4 21.9 92.4 17.1 4.1 33.3 23.1 1.7 3.7 28.1 7.2 37.5 29.5 8.9 11.3 48.2 88.2 20.0 25.9 6.8 10.2 25.8 21.9 23.4 17.4 19.5 6.6 8.6 5.9 16.0 19.9 22.1 23.3 47.9 11.6 4.2 15.1 17.5 PIK3CD p110D ENSG00000171608 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta" O00329 1 9651731-9729114 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Chemotaxis, Differentiation, Immunity, Inflammatory response, Innate immunity" "Kinase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 60.9;lymphoid tissue: 50.4" "Cell type enhanced" "Detected in many" "dendritic cells: 44.0;granulocytes: 25.3;Kupffer cells: 35.2;Microglial cells: 29.0;NK-cells: 29.9;T-cells: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 153.3;NB-4: 65.9;REH: 68.9;THP-1: 65.4;U-937: 78.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015420, HPA044953" Enhanced Approved "Vesicles,Cytokinetic bridge" Yes No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Cytokinetic bridge" "CAB015420: AB_831654, HPA044953: AB_2679153" "unprognostic (5.73e-3)" "unprognostic (2.75e-3)" "unprognostic (8.93e-2)" "unprognostic (4.05e-2)" "unprognostic (4.71e-2)" "unprognostic (1.40e-2)" "unprognostic (2.13e-1)" "unprognostic (7.42e-2)" "unprognostic (2.78e-2)" "unprognostic (1.54e-2)" "unprognostic (3.46e-2)" "unprognostic (6.75e-2)" "unprognostic (8.65e-3)" "unprognostic (2.09e-1)" "unprognostic (1.34e-1)" "unprognostic (2.04e-1)" "unprognostic (6.78e-2)" 7.2 3.1 6.8 33.4 6.3 60.9 3.9 6.1 7.5 6.2 6.4 5.4 5.2 4.9 1.7 4.9 6.1 7.0 3.3 7.0 5.3 6.4 3.5 12.0 46.9 7.3 6.6 7.0 3.0 2.9 2.8 4.2 7.8 4.6 3.4 0.6 5.1 2.7 1.2 3.0 17.2 4.7 6.6 50.4 5.7 4.0 9.3 24.3 5.5 3.5 32.0 7.4 5.1 8.5 8.1 5.2 0.4 1.4 1.3 1.1 0.7 12.1 24.5 26.0 21.1 0.3 3.3 21.5 4.9 9.8 12.4 2.4 2.0 11.0 16.2 153.3 0.4 2.4 1.3 9.0 5.1 56.0 18.7 4.3 4.5 29.2 9.8 11.4 3.8 14.9 8.0 0.1 15.0 0.6 5.4 65.9 2.2 0.3 1.4 68.9 13.0 0.7 10.9 0.0 1.7 1.5 2.7 4.9 11.9 6.8 0.8 65.4 9.8 7.7 7.9 0.2 11.5 4.9 4.9 30.1 16.7 78.6 4.4 18.0 23.5 40.2 21.6 23.0 22.6 12.8 16.3 19.9 22.5 13.6 20.9 23.1 63.2 25.9 29.2 25.7 13.3 38.3 6.8 6.3 6.1 7.5 7.0 5.3 7.3 6.6 7.8 6.6 9.3 8.5 1.7 9.6 13.4 2.0 22.2 1.5 2.2 1.8 4.0 0.7 2.0 1.7 3.1 0.0 1.1 0.0 2.1 0.3 44.0 0.1 1.9 3.9 3.0 2.0 1.7 2.7 0.0 10.3 6.7 2.0 0.5 2.9 0.0 1.0 25.3 4.2 3.6 0.0 14.7 0.0 13.4 0.1 0.0 35.2 6.0 2.8 1.2 23.1 3.6 29.0 19.3 2.5 29.9 1.0 1.1 11.3 0.0 1.5 8.2 4.1 0.2 3.8 3.3 1.3 6.6 2.0 4.7 1.5 3.4 2.9 1.1 0.3 37.1 1.5 0.2 2.1 PIMREG "CATS, FAM64A, FLJ10156, FLJ10491, RCS1" ENSG00000129195 "PICALM interacting mitotic regulator" Q9BSJ6 17 6444441-6451469 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 13.9" "Group enriched" "Detected in some" 6 "Fibroblasts: 5.5;Granulosa cells: 21.5;Hofbauer cells: 7.2;Smooth muscle cells: 14.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.1" "Immune cell enhanced" "Detected in single" "NK-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 161.8" "Region enhanced" "Detected in many" "white matter: 5.7" "Low region specificity" "Detected in single" "HPA043783, HPA049934" Uncertain Enhanced Nucleoplasm Yes Yes "Cluster 22: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA043783: AB_2678669, HPA049934: AB_2680959" "unprognostic (5.32e-3)" "unprognostic (1.14e-2)" "unprognostic (2.33e-1)" "unprognostic (4.37e-3)" "unprognostic (1.46e-1)" "unprognostic (1.24e-2)" "unprognostic (6.55e-3)" "unprognostic (1.23e-3)" "unprognostic (1.80e-1)" "unprognostic (5.88e-2)" "unprognostic (1.47e-3)" "unprognostic (1.50e-2)" "unprognostic (0.00e+0)" "unprognostic (8.65e-2)" "unprognostic (1.04e-1)" "unprognostic (1.01e-1)" "unprognostic (1.11e-1)" 0.5 2.5 0.3 1.3 0.0 2.5 0.8 1.1 0.4 0.9 0.0 3.3 3.0 0.8 0.0 3.3 0.3 0.7 0.3 0.1 0.1 0.3 0.3 0.7 1.5 0.2 0.0 0.8 0.2 0.1 0.1 0.6 0.0 0.3 4.1 0.4 0.7 0.1 0.0 2.7 3.1 2.0 0.0 6.0 1.2 0.3 0.1 13.9 0.4 0.0 2.1 1.3 1.3 0.2 42.1 54.1 161.8 73.1 1.5 4.5 12.6 47.9 29.8 78.6 52.5 32.8 17.9 0.0 18.8 39.8 39.9 29.9 82.6 21.6 41.9 64.6 33.9 0.1 33.8 41.2 0.2 1.7 48.9 2.4 1.5 32.2 12.4 8.0 24.8 36.8 10.1 23.0 49.9 30.5 9.2 0.5 70.9 34.0 37.8 74.9 64.8 29.6 12.9 6.4 36.5 51.3 41.7 42.5 39.1 20.4 19.9 4.0 11.9 59.9 48.4 36.0 80.7 8.2 31.5 0.2 23.6 20.4 94.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.1 0.0 0.1 0.2 1.0 0.1 0.0 0.3 0.3 0.3 0.0 1.1 0.4 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 1.8 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.2 0.0 0.4 1.2 0.6 0.0 0.0 0.0 0.0 0.6 5.5 0.0 0.7 1.3 21.5 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 14.5 0.0 0.0 0.0 0.0 0.1 0.8 1.1 0.0 0.0 PIN4 "EPVH, PAR14, PAR17" ENSG00000102309 "Peptidylprolyl cis/trans isomerase, NIMA-interacting 4" Q9Y237 X 72181353-72302926 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054483, HPA064504" Approved Supported "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli" "Mitotic chromosome" "HPA054483: AB_2682503, HPA064504: AB_2685274" "unprognostic (2.47e-1)" "unprognostic (6.97e-3)" "unprognostic (1.65e-1)" "unprognostic (3.77e-2)" "unprognostic (8.42e-2)" "unprognostic (1.30e-2)" "unprognostic (1.14e-2)" "prognostic favorable (6.37e-4)" "unprognostic (1.56e-1)" "unprognostic (2.13e-2)" "unprognostic (2.49e-1)" "unprognostic (9.54e-2)" "unprognostic (2.09e-3)" "unprognostic (1.92e-1)" "prognostic favorable (2.58e-4)" "unprognostic (3.34e-3)" "prognostic favorable (2.66e-4)" 14.1 14.8 23.5 10.4 24.0 8.7 16.9 25.2 36.3 15.2 24.0 16.2 11.5 14.7 21.5 14.4 12.9 7.3 19.0 23.6 24.8 19.7 28.6 10.6 10.5 24.4 24.2 16.1 13.1 20.4 13.9 11.8 24.2 15.6 12.7 18.3 16.1 10.1 19.4 10.6 12.7 10.8 24.0 13.9 15.8 5.7 23.8 17.5 16.5 20.4 11.1 13.2 14.9 25.4 36.8 41.2 42.5 29.9 28.1 23.4 23.1 24.6 26.8 28.7 29.1 20.8 26.4 11.2 68.6 25.2 39.2 25.8 38.6 43.0 35.6 26.9 83.3 18.8 51.1 55.3 14.9 29.9 14.8 15.7 22.5 32.0 11.1 32.4 29.1 32.5 32.1 46.6 20.4 43.4 25.3 49.9 30.3 42.4 36.7 25.8 34.7 32.3 37.1 24.7 27.0 48.1 28.5 13.3 27.0 32.0 20.3 25.9 30.7 13.4 19.9 36.8 17.7 15.4 18.5 17.9 38.5 28.3 14.7 42.7 37.1 40.6 41.8 41.1 41.7 49.2 43.7 40.3 38.0 45.6 44.1 44.8 15.7 41.1 39.4 44.6 58.1 39.6 23.5 24.0 25.2 36.3 23.6 24.8 24.4 24.2 24.2 24.0 23.8 25.4 68.3 67.3 48.2 14.0 44.4 43.2 63.3 167.9 36.5 26.7 67.2 94.5 84.9 78.6 89.4 119.5 8.4 162.8 44.5 99.2 181.9 125.0 13.5 78.6 66.7 71.5 92.7 71.7 17.8 117.9 89.0 59.9 45.3 56.6 57.6 46.3 92.4 288.5 110.3 28.6 17.8 93.7 128.1 72.9 44.9 9.3 74.6 50.7 60.5 7.5 69.6 90.7 80.3 16.6 27.3 136.3 114.9 81.3 38.7 51.5 162.0 296.1 95.9 42.9 85.5 65.9 94.6 19.6 42.6 51.3 46.9 120.7 44.8 53.9 88.5 54.8 PITX1 "BFT, POTX, PTX1" ENSG00000069011 "Paired like homeodomain 1" P78337 5 135027734-135034813 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 711.6;vagina: 199.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 121.0;Basal squamous epithelial cells: 409.2;Squamous epithelial cells: 1069.0;Urothelial cells: 257.3" "Cancer enhanced" "Detected in many" "cervical cancer: 73.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 141.4;HeLa: 108.9;K-562: 112.1;T-47d: 157.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA008743 Approved Approved Nucleoli Yes No "Cluster 84: Esophagus - Epithelial cell function" "Cluster 39: CACO-2 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoli "HPA008743: AB_1855413" "unprognostic (1.84e-1)" "unprognostic (1.46e-1)" "unprognostic (1.48e-1)" "unprognostic (4.62e-2)" "unprognostic (5.08e-2)" "unprognostic (5.26e-3)" "unprognostic (1.03e-2)" "unprognostic (1.66e-2)" "unprognostic (5.68e-2)" "unprognostic (2.20e-2)" "unprognostic (1.60e-2)" "unprognostic (2.27e-1)" "unprognostic (5.80e-14)" "unprognostic (6.22e-2)" "unprognostic (1.33e-1)" "unprognostic (5.98e-3)" "unprognostic (4.97e-3)" 1.5 1.9 0.7 7.7 0.6 0.3 0.6 0.9 0.7 83.5 4.7 11.4 12.1 0.8 0.0 711.6 0.5 1.1 0.2 0.9 1.1 0.1 0.3 0.4 0.1 0.8 0.9 0.6 0.4 0.0 164.7 2.7 0.7 20.1 2.0 0.1 137.5 0.0 14.1 2.0 7.9 0.4 0.5 0.2 41.9 2.2 0.7 0.0 0.2 20.1 12.6 85.0 199.0 0.8 57.5 36.9 0.0 44.7 1.4 0.9 13.4 9.6 14.6 5.1 2.3 141.4 32.5 59.9 17.6 0.9 12.6 17.6 6.4 25.5 0.3 0.7 48.2 13.4 108.9 38.4 15.6 5.8 0.1 1.4 18.4 0.0 4.9 0.3 0.1 10.1 112.1 0.2 1.9 18.4 0.6 12.3 0.1 4.8 31.8 18.5 1.1 1.2 0.6 17.9 20.2 0.1 48.4 24.1 0.0 0.5 157.5 4.2 1.5 6.1 13.4 3.5 17.0 0.1 0.2 40.7 8.1 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.9 0.7 0.9 1.1 0.8 0.9 0.7 0.5 0.7 0.8 0.1 0.0 0.0 0.0 0.2 1.3 121.0 12.8 409.2 1.0 2.5 2.7 2.3 1.5 8.6 0.0 0.0 0.8 0.0 4.2 0.0 0.2 4.2 0.3 0.6 1.2 0.0 50.8 0.0 0.4 2.1 28.8 0.5 0.2 0.0 2.7 0.0 0.0 0.9 0.0 0.0 2.4 6.1 0.0 0.3 5.7 0.3 1.0 0.0 0.0 0.0 0.4 1.0 0.0 0.1 16.9 3.4 0.0 3.1 101.6 0.3 0.2 6.1 1.8 0.0 2.1 4.5 2.2 5.6 1069.0 6.8 7.7 0.9 0.7 2.5 257.3 PKN1 "DBK, MGC46204, PAK1, PKN, PRK1, PRKCL1" ENSG00000123143 "Protein kinase N1" Q16512 19 14433053-14471867 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 102.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003982, CAB010278" Approved Approved "Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" "Cytokinetic bridge" "CAB010278: AB_2163965, HPA003982: AB_1855440" "unprognostic (3.83e-2)" "unprognostic (2.14e-1)" "unprognostic (4.13e-2)" "unprognostic (1.13e-2)" "unprognostic (1.94e-1)" "unprognostic (4.58e-1)" "unprognostic (1.30e-2)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" "unprognostic (8.55e-3)" "unprognostic (4.08e-3)" "unprognostic (2.11e-1)" "unprognostic (1.45e-2)" "unprognostic (1.70e-1)" "unprognostic (8.66e-2)" "unprognostic (4.08e-1)" "unprognostic (2.24e-2)" 59.2 45.1 47.1 40.4 50.3 66.8 49.0 44.6 52.4 46.6 44.2 72.4 14.5 61.0 13.6 16.2 48.7 23.9 89.0 40.9 46.3 43.1 25.0 71.1 49.4 53.6 48.4 38.7 52.5 32.8 44.9 33.3 49.8 43.8 9.3 11.5 41.3 30.6 81.7 20.1 45.2 33.0 49.8 90.4 51.4 50.2 49.2 35.6 39.6 53.8 25.8 60.3 32.8 48.5 152.8 88.9 32.3 67.8 51.3 59.8 53.0 53.5 63.5 55.2 52.5 34.9 84.2 144.4 135.0 92.2 68.9 34.4 52.1 23.8 21.2 117.6 67.7 172.8 55.4 75.2 169.1 68.2 103.9 43.3 17.0 33.5 52.2 62.5 129.8 74.9 78.0 96.7 41.4 62.5 104.1 63.2 59.2 54.7 100.0 138.5 43.9 104.7 27.3 24.2 117.3 166.0 33.2 41.7 88.9 15.5 37.8 117.7 196.6 108.8 46.1 133.2 82.8 126.5 123.6 78.9 71.5 135.7 87.4 27.6 27.9 40.6 30.4 38.5 23.3 15.9 20.5 21.1 26.8 16.9 18.6 21.0 32.6 22.1 52.3 17.0 25.7 29.0 47.1 50.3 44.6 52.4 40.9 46.3 53.6 48.4 49.8 49.8 49.2 48.5 78.1 3.2 2.2 17.3 35.3 3.7 6.4 1.9 1.8 37.2 17.6 14.7 4.0 27.1 3.1 35.0 16.7 2.8 77.9 4.9 1.9 28.2 4.9 27.0 25.4 49.4 40.2 17.7 3.6 30.1 14.5 20.8 30.1 20.7 2.5 80.9 53.2 11.3 59.8 48.8 8.6 10.9 8.2 69.0 17.0 8.4 19.9 56.2 17.8 17.8 48.2 61.2 102.0 7.5 11.9 64.2 10.6 23.0 27.1 12.7 1.1 15.2 12.4 29.2 26.3 21.7 29.2 9.3 42.2 1.3 2.7 3.7 55.5 34.3 4.8 4.9 PKN2 "Pak-2, PRK2, PRKCL2, STK7" ENSG00000065243 "Protein kinase N2" Q16513 1 88684222-88836255 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion, Cell cycle, Cell division, Cilium biogenesis/degradation, Host-virus interaction, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 80.5" "Lineage enriched" "Detected in all" 8 "granulocytes: 80.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034861, HPA057913" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Intermediate filaments,Centrosome,Cytosol" Yes No "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 15: RT4 - Unknown function" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Intermediate filaments" "Nuclear bodies, Plasma membrane, Centrosome, Cytosol" "HPA034861: AB_2674363, HPA057913: AB_2732617" "unprognostic (7.52e-2)" "unprognostic (1.46e-1)" "prognostic favorable (5.67e-4)" "unprognostic (5.95e-2)" "unprognostic (3.39e-2)" "unprognostic (2.51e-2)" "unprognostic (4.64e-3)" "unprognostic (1.38e-1)" "unprognostic (4.43e-2)" "unprognostic (1.27e-2)" "unprognostic (2.90e-3)" "unprognostic (1.23e-1)" "unprognostic (1.51e-2)" "unprognostic (5.98e-2)" "unprognostic (2.38e-1)" "unprognostic (1.01e-2)" "unprognostic (1.99e-1)" 19.3 16.5 9.3 17.6 14.2 48.7 24.1 20.7 10.9 16.4 17.0 23.9 30.5 23.6 25.0 24.7 18.1 17.1 14.1 9.5 9.7 16.9 20.5 20.4 18.2 12.3 10.4 31.2 15.5 22.3 10.1 24.7 12.7 20.3 30.0 26.7 16.3 15.4 9.8 20.3 30.8 18.5 10.1 19.0 20.9 10.5 12.6 17.8 26.1 13.4 17.4 21.3 15.4 17.6 61.1 23.8 45.2 27.3 29.8 33.6 29.6 35.3 32.2 38.5 39.8 25.3 42.5 23.9 41.0 33.6 47.3 46.7 44.7 26.6 52.4 8.6 33.0 17.7 49.3 21.4 26.2 17.6 5.1 27.7 27.1 30.2 36.3 30.6 44.7 18.6 29.9 16.8 42.2 12.2 20.5 15.2 22.8 23.1 27.1 19.3 68.8 9.8 34.3 117.9 22.0 14.5 52.7 29.8 45.7 33.9 22.5 15.7 42.2 32.5 29.2 42.1 37.2 9.2 8.6 16.6 13.6 17.1 12.6 15.3 9.9 16.6 5.7 5.9 5.1 8.0 5.1 5.3 5.0 9.3 6.6 5.6 80.5 3.5 8.0 8.6 4.6 2.7 9.3 14.2 20.7 10.9 9.5 9.7 12.3 10.4 12.7 10.1 12.6 17.6 104.7 41.7 57.8 102.5 52.5 48.4 44.3 33.3 75.1 85.4 60.2 67.9 50.8 38.6 47.9 69.9 89.6 42.9 48.1 101.5 11.7 61.2 2.6 63.7 68.7 59.5 44.3 57.7 134.2 60.7 33.1 53.1 85.6 84.6 15.8 107.0 47.5 39.4 24.2 65.6 130.8 64.3 32.6 35.8 27.9 6.6 54.3 44.9 32.0 178.0 57.3 50.5 22.6 117.1 146.4 77.6 98.1 48.2 54.8 64.7 84.0 26.7 49.1 150.5 39.5 62.8 55.5 43.6 34.6 83.0 52.4 37.4 44.8 90.2 65.0 124.2 PKNOX2 ENSG00000165495 "PBX/knotted 1 homeobox 2" Q96KN3 11 125164687-125433389 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 36.3" "Cell type enhanced" "Detected in many" "Astrocytes: 31.3;Early spermatids: 46.8;Excitatory neurons: 132.9;Inhibitory neurons: 137.4;Oligodendrocyte precursor cells: 85.5" "Cancer enhanced" "Detected in many" "melanoma: 8.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 39.1;AN3-CA: 9.6;hTEC/SVTERT24-B: 7.8;LHCN-M2: 11.6;SK-MEL-30: 7.8;WM-115: 21.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028867, CAB034342, HPA055368, HPA066962" Supported Enhanced "Nucleoplasm,Cytokinetic bridge" Yes NA "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Cytokinetic bridge" "CAB034342: AB_2164138, HPA028867: AB_2672802, HPA055368: AB_2682796, HPA066962: AB_2685757" "unprognostic (2.91e-2)" "unprognostic (1.62e-1)" "unprognostic (2.10e-2)" "unprognostic (7.26e-2)" "unprognostic (9.46e-2)" "unprognostic (3.97e-2)" "unprognostic (2.41e-1)" "unprognostic (2.12e-2)" "unprognostic (1.56e-1)" "unprognostic (2.44e-2)" "unprognostic (7.66e-2)" "unprognostic (3.70e-1)" "unprognostic (4.10e-6)" "unprognostic (1.76e-3)" "unprognostic (7.11e-2)" "unprognostic (1.71e-2)" "unprognostic (6.48e-3)" 3.6 3.3 2.6 2.0 5.8 0.0 1.2 1.4 12.7 3.2 8.1 2.8 0.9 3.3 2.7 1.4 6.1 1.8 7.3 4.8 0.6 3.0 0.5 10.0 1.4 3.0 0.3 14.9 3.9 0.9 5.6 8.4 1.3 6.3 1.4 2.8 2.5 5.1 15.0 2.4 1.7 2.6 2.6 2.3 2.3 4.8 0.8 3.1 12.1 36.3 1.1 3.1 2.7 3.1 0.0 0.0 39.1 9.6 0.7 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 4.8 0.0 0.0 0.2 0.2 0.0 0.0 0.0 1.2 0.0 0.0 2.0 0.0 7.8 0.1 0.0 0.0 0.0 0.0 0.0 11.6 0.3 0.0 0.0 3.9 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.8 6.1 0.0 0.2 0.0 2.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 21.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 5.8 1.4 12.7 4.8 0.6 3.0 0.3 1.3 2.6 0.8 3.1 0.6 0.0 0.0 31.3 0.0 0.9 0.0 0.0 0.0 0.9 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 1.4 46.8 0.0 1.1 0.5 0.0 0.0 132.9 0.2 0.0 3.1 0.0 0.0 0.0 12.2 1.8 0.0 0.3 8.4 137.4 0.0 0.0 0.0 0.3 9.6 5.0 0.0 8.8 22.5 0.0 2.9 0.0 85.5 3.8 0.1 0.0 17.7 0.0 1.9 0.0 0.1 0.0 0.3 6.6 8.8 2.9 1.2 0.4 0.0 0.4 0.1 0.0 6.9 0.0 0.0 PLEKHA4 PEPP1 ENSG00000105559 "Pleckstrin homology domain containing A4" Q9H4M7 19 48837097-48868617 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Peritubular cells: 53.4;Smooth muscle cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 63.4;BJ hTERT+ SV40 Large T+ RasG12V: 49.5;SK-MEL-30: 77.0" "Low region specificity" "Detected in some" "Region enriched" "Detected in many" 6 "spinal cord: 45.0" "HPA042978, HPA048473" Uncertain Approved "Plasma membrane,Cytokinetic bridge,Centriolar satellite,Cytosol" Yes No "Cluster 21: B-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Cytosol" "Cytokinetic bridge, Centriolar satellite" "HPA042978: AB_2678249, HPA048473: AB_2680409" "prognostic favorable (1.97e-4)" "unprognostic (4.39e-1)" "unprognostic (8.16e-2)" "unprognostic (2.85e-2)" "unprognostic (3.98e-1)" "unprognostic (4.20e-2)" "prognostic unfavorable (8.68e-4)" "unprognostic (5.09e-2)" "unprognostic (1.01e-2)" "unprognostic (1.17e-1)" "unprognostic (1.18e-2)" "unprognostic (2.95e-1)" "unprognostic (3.84e-2)" "unprognostic (1.35e-1)" "unprognostic (1.67e-1)" "unprognostic (1.08e-3)" "unprognostic (6.38e-2)" 34.0 24.6 8.8 12.1 8.8 0.7 31.7 8.0 9.5 28.7 10.9 43.0 5.6 34.6 5.0 14.3 30.5 11.1 41.4 8.7 10.6 32.4 32.8 25.7 5.8 16.9 14.7 47.5 13.2 9.5 29.9 5.6 10.4 28.3 3.9 2.5 15.1 8.4 19.3 17.2 16.0 10.7 10.8 16.2 21.1 11.0 12.4 5.5 31.0 13.1 3.3 34.4 21.7 10.3 9.0 0.5 9.9 63.4 14.2 41.7 8.0 7.0 24.7 26.8 49.5 5.9 2.5 0.4 11.8 9.8 10.4 2.7 3.5 3.6 4.2 0.0 3.4 2.3 1.7 6.6 11.0 0.0 14.2 21.5 2.2 15.6 1.0 11.1 8.0 11.2 9.5 5.3 7.4 5.4 3.2 0.5 1.5 6.0 0.8 0.3 31.5 0.6 8.3 0.1 0.0 11.0 3.0 2.6 77.0 2.5 3.9 3.0 1.3 8.5 6.8 11.2 1.8 28.3 25.4 5.3 10.2 0.7 23.0 0.0 0.3 0.9 1.8 0.3 1.3 1.7 1.7 1.1 0.1 3.9 2.8 2.6 0.1 0.8 0.3 1.2 0.6 0.9 8.8 8.8 8.0 9.5 8.7 10.6 16.9 14.7 10.4 10.8 12.4 10.3 6.4 0.0 18.7 2.3 1.4 9.6 31.3 17.6 12.0 0.7 11.4 18.3 37.1 17.2 27.2 7.3 0.0 3.3 2.9 3.2 1.9 23.3 0.8 11.6 34.1 7.0 1.2 3.2 0.4 5.1 6.8 41.7 7.7 11.6 0.0 18.8 6.4 13.3 2.9 0.0 0.5 2.5 4.1 0.8 9.2 2.0 41.3 1.9 12.4 1.9 1.3 9.9 2.1 0.5 0.2 6.9 0.5 53.4 0.7 29.8 0.7 14.6 20.5 1.0 6.6 33.0 48.4 4.0 3.7 5.7 9.8 2.9 2.4 16.0 3.3 21.4 PLEKHG1 "ARHGEF41, KIAA1209" ENSG00000120278 "Pleckstrin homology and RhoGEF domain containing G1" Q9ULL1 6 150599883-150843665 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 31.2" "Cell type enhanced" "Detected in many" "Adipocytes: 91.2;Astrocytes: 98.6;Endothelial cells: 58.4;Microglial cells: 131.2;Oligodendrocytes: 168.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 31 "memory B-cell: 23.9;naive B-cell: 22.9" "Lineage enriched" "Detected in single" 31 "B-cells: 23.9" "Cell line enhanced" "Detected in many" "AF22: 17.6;HAP1: 26.4;Karpas-707: 23.4;U-698: 16.6" "Region enhanced" "Detected in all" "thalamus: 51.3" "Low region specificity" "Detected in all" "HPA027128, HPA027319, HPA028270" Approved Enhanced Nucleoplasm Yes No "Cluster 37: B-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA027128: AB_2672124, HPA027319: AB_10600306, HPA028270: AB_10611388" "unprognostic (2.93e-1)" "unprognostic (3.44e-1)" "unprognostic (3.04e-3)" "unprognostic (2.34e-1)" "unprognostic (1.05e-1)" "unprognostic (2.80e-3)" "unprognostic (1.85e-1)" "unprognostic (4.82e-2)" "unprognostic (2.10e-1)" "unprognostic (1.60e-1)" "unprognostic (3.47e-2)" "unprognostic (1.50e-1)" "unprognostic (4.62e-3)" "unprognostic (3.63e-1)" "unprognostic (4.30e-2)" "unprognostic (3.83e-1)" "unprognostic (2.15e-2)" 15.1 1.6 9.8 9.4 12.3 2.4 13.7 15.5 8.9 7.5 3.9 5.9 4.9 5.6 10.8 9.4 8.7 7.9 6.9 5.8 8.7 7.7 4.9 10.4 14.7 19.5 16.2 3.1 2.7 6.7 3.6 14.2 18.3 2.7 5.9 4.7 3.5 4.9 3.5 7.4 6.6 5.6 18.2 31.2 4.5 6.3 19.1 22.4 5.7 5.0 13.9 9.1 5.3 21.5 0.0 0.2 17.6 0.1 0.0 0.0 12.6 0.0 0.0 0.0 0.0 10.1 4.4 7.2 6.8 0.0 1.6 2.5 26.4 2.4 0.0 11.4 2.9 0.4 1.4 0.0 0.0 0.0 1.9 1.1 6.7 0.0 0.2 0.0 11.0 5.9 0.0 23.4 0.0 0.3 2.3 0.1 1.3 7.0 0.7 1.2 0.0 0.0 5.1 11.9 0.5 0.1 0.1 3.1 2.2 1.9 0.0 0.1 11.2 0.1 2.4 0.0 4.9 0.0 0.0 16.6 0.0 0.0 3.6 0.0 0.0 0.0 0.1 0.0 0.7 23.9 0.4 0.6 0.0 22.9 0.0 0.6 0.0 0.0 0.0 0.0 0.5 0.7 9.8 12.3 15.5 8.9 5.8 8.7 19.5 16.2 18.3 18.2 19.1 21.5 91.2 0.0 6.2 98.6 50.3 4.2 0.5 5.5 2.8 0.9 2.0 3.3 2.1 1.5 6.8 7.3 0.0 5.5 0.7 7.2 3.9 2.6 3.8 20.7 6.2 58.4 5.4 5.0 12.8 1.1 1.6 11.8 7.1 19.2 0.0 7.9 35.0 4.3 0.6 0.0 5.8 8.2 8.2 5.9 3.8 1.6 0.3 2.0 5.4 131.2 4.7 11.3 0.0 14.1 168.5 9.4 12.4 0.4 5.2 1.1 3.9 3.6 9.6 0.7 0.0 2.0 3.0 0.7 1.5 6.2 3.7 2.9 5.1 1.1 5.5 3.6 PLEKHG3 "ARHGEF43, KIAA0599" ENSG00000126822 "Pleckstrin homology and RhoGEF domain containing G3" A1L390 14 64704102-64750249 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 179.2" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 90.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 24.0;NK-cells: 9.4;T-cells: 16.2" "Cell line enhanced" "Detected in many" "A-431: 78.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063455, HPA065323, HPA073702, HPA074734" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Centrosome,Cytosol" Yes No "Cluster 5: Granulocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoplasm, Cytokinetic bridge, Centrosome" "HPA063455: AB_2685015, HPA065323: AB_2685467, HPA073702: AB_2732238, HPA074734: AB_2732265" "unprognostic (8.71e-2)" "unprognostic (1.69e-1)" "unprognostic (4.38e-2)" "unprognostic (4.04e-2)" "unprognostic (2.18e-1)" "unprognostic (7.22e-2)" "unprognostic (7.21e-2)" "unprognostic (5.53e-3)" "unprognostic (1.49e-1)" "unprognostic (3.34e-3)" "unprognostic (3.63e-1)" "unprognostic (3.54e-2)" "prognostic favorable (7.39e-8)" "unprognostic (2.29e-1)" "unprognostic (2.67e-1)" "unprognostic (4.24e-2)" "unprognostic (2.67e-3)" 25.2 3.5 44.0 10.7 92.5 16.3 23.4 47.2 74.1 33.9 53.0 39.0 13.0 67.5 5.0 45.8 38.1 22.6 17.2 44.5 46.7 36.0 36.3 14.3 5.6 65.8 66.3 33.8 33.0 17.0 6.8 29.3 60.9 24.2 15.5 2.9 29.2 37.5 9.7 44.9 13.2 26.4 37.9 26.6 22.3 5.7 74.1 4.6 23.7 7.4 4.9 32.2 39.1 179.2 78.4 36.5 29.8 45.3 3.1 0.0 49.0 8.7 10.4 13.8 11.0 38.9 34.3 0.0 15.3 8.6 4.8 74.6 20.3 69.7 4.7 0.2 16.7 35.1 48.3 9.2 4.0 1.3 16.1 3.9 39.6 2.9 24.4 22.9 9.1 0.3 0.0 0.4 4.6 37.5 0.1 32.0 10.0 21.2 37.0 0.4 14.7 5.5 37.0 58.0 9.9 18.0 17.7 26.7 25.1 27.5 29.0 8.0 16.6 6.0 59.8 0.3 12.3 0.1 0.2 0.1 0.6 3.7 10.7 9.0 3.0 18.2 16.2 1.5 11.1 0.0 5.0 7.3 1.0 0.0 0.5 3.6 24.0 9.4 1.0 0.0 1.7 5.3 44.0 92.5 47.2 74.1 44.5 46.7 65.8 66.3 60.9 37.9 74.1 179.2 3.1 3.2 6.2 15.0 0.7 19.4 19.4 15.1 21.6 5.5 16.0 9.8 7.8 12.8 6.0 47.8 0.0 7.9 14.5 24.7 11.7 26.7 0.9 18.6 18.5 4.0 34.7 0.4 1.0 20.6 9.5 7.4 14.3 23.6 1.3 1.9 3.6 10.1 5.5 0.0 3.2 26.9 18.3 6.5 8.0 1.5 7.5 2.7 5.4 6.5 4.6 9.1 45.3 10.6 90.9 35.3 16.7 25.6 2.8 16.1 2.3 9.5 4.0 0.8 26.3 5.1 25.3 0.2 1.6 25.6 21.5 2.6 9.0 10.5 13.2 32.2 POLR3E "C37, FLJ10509, RPC5, SIN" ENSG00000058600 "RNA polymerase III subunit E" Q9NVU0 16 22297375-22335101 "Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 62.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041419, HPA041477" Approved Enhanced Nucleoplasm Yes No "Cluster 39: Non-specific - mRNA processing" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA041419: AB_2677468, HPA041477: AB_10796345" "unprognostic (3.09e-2)" "unprognostic (8.59e-2)" "unprognostic (8.23e-2)" "unprognostic (1.04e-1)" "unprognostic (1.51e-1)" "unprognostic (7.28e-2)" "unprognostic (2.42e-2)" "unprognostic (7.73e-2)" "unprognostic (2.96e-2)" "unprognostic (1.34e-1)" "unprognostic (2.03e-1)" "prognostic unfavorable (1.74e-4)" "unprognostic (8.14e-2)" "unprognostic (1.91e-1)" "unprognostic (8.96e-2)" "unprognostic (8.19e-3)" "unprognostic (3.41e-2)" 12.2 17.0 2.8 6.6 4.5 7.8 12.0 4.3 3.7 10.7 16.1 12.9 6.3 12.7 2.4 13.0 11.8 4.5 15.4 4.1 4.4 8.4 13.3 10.2 5.3 4.8 5.5 11.3 16.1 10.7 12.8 4.6 4.5 11.3 3.0 3.1 12.2 8.2 62.6 14.8 10.0 4.9 3.7 8.9 14.2 11.2 4.2 8.5 12.8 15.5 5.7 12.0 10.4 5.3 21.1 29.0 6.9 19.5 12.1 9.7 27.5 16.1 6.1 9.4 4.2 36.3 14.8 41.7 21.8 11.1 7.9 18.7 35.6 20.6 7.6 28.7 52.3 21.0 31.8 70.9 15.1 34.4 23.0 8.7 19.5 22.1 25.8 3.5 25.9 17.1 63.1 17.0 10.9 34.5 33.6 11.8 37.5 20.2 22.8 45.0 16.7 54.2 8.0 12.4 28.9 20.6 15.6 29.2 14.0 4.2 17.2 16.3 17.3 11.0 12.4 9.2 18.3 23.6 45.6 40.3 11.1 23.0 21.1 0.0 4.7 2.8 8.6 4.8 9.1 7.4 9.1 8.7 7.7 6.0 8.4 7.3 0.5 7.4 4.5 4.4 10.0 6.9 2.8 4.5 4.3 3.7 4.1 4.4 4.8 5.5 4.5 3.7 4.2 5.3 9.4 3.2 14.7 14.4 20.3 32.5 23.0 10.9 12.5 24.0 16.4 19.7 18.9 11.5 13.4 18.4 31.3 25.2 27.3 8.9 5.9 12.0 34.9 21.0 13.3 13.3 15.0 10.5 12.8 12.8 20.2 14.1 13.7 28.5 27.9 23.1 8.9 11.1 13.1 20.2 16.3 13.7 10.2 10.1 22.2 20.9 12.5 11.0 14.2 11.2 9.7 10.4 21.6 18.6 17.9 15.0 11.7 9.1 26.0 28.5 13.6 11.8 16.6 40.9 13.1 21.0 12.2 19.7 16.1 16.5 39.6 28.3 30.3 20.5 16.2 26.3 PPAT "GPAT, PRAT" ENSG00000128059 "Phosphoribosyl pyrophosphate amidotransferase" Q06203 4 56393362-56435615 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Purine biosynthesis" "Allosteric enzyme, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 66.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036091, HPA036092" Approved Approved "Midbody ring" Yes No 11000 "Cluster 27: Non-specific - Gene expression" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 40: Granulosa cells - Unknown function" "Midbody ring" "HPA036091: AB_2674936, HPA036092: AB_10603132" "unprognostic (5.11e-2)" "unprognostic (5.13e-2)" "unprognostic (1.39e-2)" "prognostic unfavorable (5.15e-5)" "unprognostic (1.38e-1)" "unprognostic (4.37e-3)" "prognostic unfavorable (1.14e-8)" "unprognostic (6.74e-3)" "unprognostic (2.95e-2)" "unprognostic (3.79e-2)" "unprognostic (2.88e-3)" "unprognostic (1.51e-1)" "prognostic unfavorable (8.34e-4)" "unprognostic (1.41e-1)" "unprognostic (3.01e-1)" "prognostic unfavorable (1.95e-4)" "unprognostic (1.09e-1)" 2.8 6.1 3.8 5.4 4.0 5.6 7.1 3.7 4.7 4.3 3.6 3.9 4.0 4.6 3.4 4.5 4.4 3.0 2.3 4.1 4.0 6.0 6.1 2.2 8.4 3.4 4.0 7.4 5.9 3.9 2.5 6.7 4.3 3.9 4.8 4.4 5.6 3.1 2.9 4.3 3.2 3.6 3.7 4.3 3.5 8.6 4.1 8.3 5.9 2.9 8.0 6.7 2.6 4.2 23.1 19.0 38.0 18.7 12.2 15.7 31.0 25.2 11.1 20.4 21.6 38.1 27.5 80.6 33.4 11.9 19.0 16.8 74.0 25.4 40.7 21.1 32.8 32.6 22.6 42.2 18.4 65.0 19.5 13.6 19.4 29.0 32.4 12.6 21.8 32.5 83.5 43.3 23.2 20.9 80.6 49.1 50.6 52.0 22.4 67.2 24.9 56.9 34.2 16.2 64.0 31.2 20.1 36.3 23.0 35.4 24.5 13.8 15.3 21.2 36.6 21.4 45.0 32.2 34.5 82.9 23.6 40.7 20.1 4.7 1.8 0.9 3.8 2.7 5.9 7.4 5.1 5.2 2.5 6.1 7.7 7.1 0.5 10.2 3.9 3.2 4.3 3.5 3.8 4.0 3.7 4.7 4.1 4.0 3.4 4.0 4.3 3.7 4.1 4.2 4.8 0.0 5.5 16.6 10.7 31.0 16.0 5.6 28.5 8.4 10.1 9.7 3.8 4.3 8.0 3.7 2.1 29.7 10.3 1.5 9.8 3.7 2.6 5.5 14.1 7.8 4.2 14.9 22.9 2.7 25.2 9.4 4.1 6.9 7.0 66.2 5.3 7.1 7.9 38.7 15.8 4.3 4.1 1.6 6.0 2.6 7.8 5.2 8.8 5.6 3.1 6.4 2.1 5.5 9.1 3.3 2.7 5.7 15.3 15.0 0.8 12.7 6.2 4.7 0.0 9.3 10.8 16.4 27.5 18.3 31.8 7.7 10.7 21.9 9.0 8.7 PPDPF "C20orf149, dJ697K14.9, exdpf" ENSG00000125534 "Pancreatic progenitor cell differentiation and proliferation factor" Q9H3Y8 20 63520765-63522206 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 2997.4;Paneth cells: 2752.7;Proximal enterocytes: 2849.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "eosinophil: 26.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 26.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040929 Approved Nucleoplasm,Nucleoli,Microtubules Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Microtubules" Nucleoli "HPA040929: AB_10794155" "unprognostic (3.75e-2)" "unprognostic (5.39e-2)" "unprognostic (4.37e-2)" "unprognostic (9.03e-2)" "unprognostic (1.07e-1)" "unprognostic (2.38e-2)" "unprognostic (2.03e-2)" "unprognostic (2.42e-1)" "unprognostic (3.43e-2)" "unprognostic (1.91e-1)" "unprognostic (2.00e-1)" "unprognostic (4.20e-1)" "prognostic favorable (3.91e-4)" "unprognostic (1.04e-1)" "unprognostic (1.03e-1)" "unprognostic (4.20e-1)" "unprognostic (2.09e-2)" 215.1 72.2 192.7 71.1 203.3 79.6 237.4 194.7 262.1 312.4 108.7 298.3 81.3 217.8 43.8 622.2 185.6 40.8 412.9 164.7 189.8 421.8 134.9 243.4 42.2 220.9 217.1 197.5 197.9 47.1 196.8 30.3 221.9 365.0 60.6 25.6 432.4 93.4 438.3 461.5 167.1 53.4 201.1 117.0 298.8 129.3 202.5 32.1 249.8 64.2 47.3 264.0 410.7 253.9 287.2 87.8 57.9 118.5 65.4 107.9 185.4 169.1 54.1 217.5 85.2 162.8 166.3 60.7 222.8 115.2 83.2 294.3 29.5 196.0 35.5 110.5 58.5 24.8 83.0 31.9 175.3 0.2 124.3 106.5 384.9 55.3 76.4 72.7 86.5 74.9 104.5 138.9 81.1 394.9 288.7 2.7 63.3 228.1 494.5 132.0 132.2 125.7 159.8 117.4 197.1 150.9 170.3 272.6 124.4 39.1 390.7 168.8 147.3 184.1 206.9 245.8 143.5 108.9 93.3 41.1 130.7 70.9 122.6 2.3 3.0 26.0 5.7 3.6 4.7 5.0 5.1 5.4 3.4 5.8 4.3 5.2 1.2 3.0 5.7 4.0 5.7 5.7 192.7 203.3 194.7 262.1 164.7 189.8 220.9 217.1 221.9 201.1 202.5 253.9 328.1 314.1 220.3 15.7 462.8 574.5 714.7 1076.0 375.6 51.8 1282.8 1173.8 70.1 906.5 763.6 960.0 12.5 428.4 422.5 2528.3 2997.4 916.1 222.0 440.1 449.6 294.2 796.4 399.0 15.4 755.9 761.0 430.8 1120.8 520.2 337.8 293.3 376.3 224.2 600.6 50.5 12.5 1549.5 850.4 390.4 755.8 1154.3 371.9 366.4 1191.7 6.5 831.8 236.9 435.6 6.6 67.2 971.0 2752.7 288.5 280.4 1021.9 2849.8 1715.5 542.0 60.0 197.2 216.3 541.5 129.0 261.6 1559.8 932.1 414.1 541.7 158.5 1132.9 1492.7 PPEF1 "PPEF, PPP7CA" ENSG00000086717 "Protein phosphatase with EF-hand domain 1" O14829 X 18675909-18827921 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 5.8;testis: 14.6" "Group enriched" "Detected in some" 9 "Early spermatids: 64.0;Late spermatids: 139.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.1;HeLa: 1.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034577 Uncertain "Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 78: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "Cytokinetic bridge" "HPA034577: AB_10602817" "unprognostic (4.13e-2)" "unprognostic (1.30e-1)" "unprognostic (9.06e-2)" "unprognostic (9.85e-2)" "unprognostic (3.84e-2)" "unprognostic (5.00e-2)" "unprognostic (2.38e-1)" "unprognostic (3.43e-2)" "unprognostic (4.96e-3)" "unprognostic (9.29e-2)" "unprognostic (1.70e-1)" "unprognostic (2.89e-1)" "unprognostic (1.10e-11)" "unprognostic (5.41e-3)" "unprognostic (2.75e-1)" "unprognostic (2.97e-2)" "unprognostic (1.19e-2)" 0.1 0.2 1.3 0.0 2.0 1.0 2.3 1.8 2.6 0.1 0.8 0.1 0.0 0.1 0.5 0.0 0.1 0.1 0.3 1.6 1.4 0.2 0.1 0.3 0.1 3.5 2.1 0.2 0.1 0.0 0.5 0.6 2.4 0.4 0.0 1.4 0.1 0.3 0.1 0.4 0.1 0.0 1.8 0.2 0.1 14.6 1.5 0.1 0.2 0.0 0.1 0.2 0.1 5.8 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.0 1.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.0 1.8 2.6 1.6 1.4 3.5 2.1 2.4 1.8 1.5 5.8 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 64.0 0.0 0.0 0.1 0.0 0.0 11.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.7 4.7 0.0 0.0 0.0 0.3 139.0 0.6 0.0 3.6 1.0 0.1 0.6 0.0 0.5 2.2 0.0 0.0 0.7 0.0 0.1 0.0 0.2 0.0 0.6 0.0 0.0 1.2 1.2 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 PPM1E "CaMKP-N, KIAA1072, POPX1, PP2CH" ENSG00000175175 "Protein phosphatase, Mg2+/Mn2+ dependent 1E" Q8WY54 17 58755854-58985179 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 39.2;retina: 22.3" "Group enriched" "Detected in some" 4 "Excitatory neurons: 220.9;Horizontal cells: 77.4;Inhibitory neurons: 288.4;Oligodendrocyte precursor cells: 109.1" "Cancer enhanced" "Detected in some" "glioma: 2.7;prostate cancer: 3.0" "Group enriched" "Detected in many" 4 "cerebral cortex: 31.6;hippocampal formation: 39.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 12.2;HAP1: 19.9;MOLT-4: 9.9;SCLC-21H: 9.1;SH-SY5Y: 18.7;THP-1: 8.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018462, HPA019263" Approved Approved Nucleoplasm,Nucleoli Yes No "Cluster 46: Basophils - DNA binding" "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoli Nucleoplasm "HPA018462: AB_1855623, HPA019263: AB_1855624" "unprognostic (2.50e-2)" "unprognostic (5.75e-2)" "unprognostic (8.12e-2)" "unprognostic (2.99e-2)" "unprognostic (5.30e-1)" "unprognostic (8.19e-2)" "unprognostic (3.96e-1)" "unprognostic (1.52e-1)" "unprognostic (3.22e-2)" "unprognostic (5.24e-2)" "unprognostic (8.80e-5)" "unprognostic (4.97e-2)" "unprognostic (1.23e-7)" "unprognostic (1.05e-4)" "unprognostic (1.64e-2)" "unprognostic (1.27e-1)" "unprognostic (9.12e-2)" 0.1 5.5 5.3 0.1 4.8 0.0 0.1 1.0 31.6 0.2 0.0 0.1 0.1 0.3 0.9 0.0 1.5 0.1 1.0 39.2 7.3 0.7 1.0 0.2 0.2 1.9 4.2 0.2 0.6 0.3 1.3 0.0 3.2 1.4 0.0 22.3 0.2 0.0 0.0 0.0 0.2 0.3 0.3 0.2 0.5 6.7 8.0 0.2 0.1 0.1 0.2 0.1 0.1 2.3 0.0 0.1 12.2 0.6 0.0 0.0 0.9 0.0 0.0 0.9 1.4 0.0 0.0 8.0 0.1 0.1 2.7 0.0 19.9 0.0 0.5 0.2 5.9 0.0 0.2 0.0 1.3 0.6 2.6 0.3 1.6 0.1 0.0 0.6 0.0 4.9 2.1 0.0 0.0 3.6 9.9 0.0 3.5 0.0 1.0 0.0 1.5 0.0 0.0 0.0 9.1 18.7 0.3 0.0 1.3 0.1 0.0 8.7 0.0 0.0 2.2 0.0 2.9 0.1 0.1 5.4 0.3 0.0 2.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 4.8 1.0 31.6 39.2 7.3 1.9 4.2 3.2 0.3 8.0 2.3 0.1 0.0 0.0 32.7 0.0 0.0 0.0 0.0 0.0 22.0 0.1 0.4 3.3 0.0 1.8 0.0 31.3 0.0 0.0 0.1 0.0 0.0 30.8 3.9 0.1 0.3 3.0 0.0 220.9 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.0 1.4 0.1 77.4 288.4 0.0 0.0 0.3 0.0 17.6 0.0 0.1 0.0 5.6 0.0 4.2 0.0 109.1 38.4 0.0 0.2 0.4 0.0 1.3 0.0 0.1 0.0 13.8 0.0 0.0 0.5 12.1 2.8 0.0 0.0 0.0 0.0 0.8 0.0 0.0 PPP1R3E FLJ00089 ENSG00000235194 "Protein phosphatase 1 regulatory subunit 3E" Q9H7J1 14 23295652-23302859 "Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 47.0" "Cell type enhanced" "Detected in all" "Early spermatids: 111.9;Late spermatids: 62.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 41.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA061600 Approved Approved "Microtubules,Mitotic spindle,Mitochondria" Yes No "Cluster 51: Monocytes - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 29: U-266 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Microtubules, Mitochondria" "Mitotic spindle" "HPA061600: AB_2684566" "unprognostic (3.45e-2)" "unprognostic (1.57e-2)" "prognostic unfavorable (6.89e-5)" "unprognostic (4.05e-1)" "unprognostic (2.85e-2)" "unprognostic (1.29e-2)" "unprognostic (7.12e-2)" "prognostic favorable (3.10e-4)" "unprognostic (1.73e-2)" "unprognostic (1.18e-1)" "unprognostic (1.77e-3)" "unprognostic (2.41e-1)" "unprognostic (8.67e-3)" "unprognostic (8.46e-2)" "unprognostic (2.88e-1)" "unprognostic (8.12e-2)" "unprognostic (5.46e-2)" 5.8 8.0 15.2 5.7 17.9 3.9 6.4 17.9 23.8 10.2 9.7 7.4 6.3 6.4 10.1 6.0 9.5 3.3 6.2 15.0 15.3 11.6 11.2 5.7 9.5 18.5 16.5 12.5 10.6 5.7 19.3 2.7 19.4 12.1 5.9 47.0 8.5 6.2 14.9 10.9 13.3 3.4 13.8 15.1 9.0 14.7 17.7 8.2 14.9 5.4 8.2 7.9 8.5 23.3 1.1 3.0 3.6 2.5 6.9 2.9 1.7 1.2 2.2 2.0 1.7 1.7 5.8 11.2 0.8 1.6 2.2 7.6 2.1 1.2 2.5 4.0 2.1 2.0 6.9 4.0 1.8 2.3 4.4 2.5 4.5 1.2 6.1 3.3 0.9 6.0 1.9 9.8 1.7 2.6 2.1 3.6 0.9 3.6 2.8 3.4 2.5 7.2 1.1 2.5 4.5 1.2 1.8 1.6 1.2 1.8 1.9 0.8 1.7 2.4 1.3 4.1 0.9 41.1 4.6 5.1 1.9 4.0 1.5 0.2 0.4 0.2 0.5 1.4 0.6 1.0 0.1 0.2 0.3 0.6 0.5 0.3 0.4 0.2 1.8 0.3 0.4 0.3 15.2 17.9 17.9 23.8 15.0 15.3 18.5 16.5 19.4 13.8 17.7 23.3 5.8 3.2 4.8 30.0 25.4 5.6 9.0 5.3 11.4 59.4 7.8 11.6 8.8 7.2 5.0 20.2 37.5 8.2 12.8 8.0 5.9 2.1 111.9 3.7 6.6 7.2 8.4 7.2 25.0 3.3 2.0 6.1 20.4 4.3 3.8 9.4 7.5 7.2 7.4 32.0 33.0 7.7 4.1 9.5 9.6 62.9 27.4 9.2 10.6 15.9 8.1 20.4 26.8 16.1 56.1 2.4 11.6 25.9 11.9 6.7 19.5 9.5 4.8 38.1 13.1 3.5 5.4 36.5 13.9 8.4 9.1 5.2 15.7 7.2 9.6 8.6 PRC1 ASE1 ENSG00000198901 "Protein regulator of cytokinesis 1" O43663 15 90966040-90995629 "Predicted intracellular proteins" "Cell cycle, Cell division" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 89.9;testis: 55.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 142.9;Extravillous trophoblasts: 68.3;Spermatocytes: 136.4;Spermatogonia: 74.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 34.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 34.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034521, HPA048816" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Cytokinetic bridge,Midbody" Yes Yes "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Microtubules, Cytokinetic bridge, Midbody" Nucleoplasm "HPA034521: AB_10670169, HPA048816: " "unprognostic (1.14e-1)" "unprognostic (3.98e-2)" "unprognostic (9.21e-2)" "unprognostic (1.75e-3)" "unprognostic (2.39e-1)" "unprognostic (3.43e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.24e-3)" "unprognostic (3.86e-3)" "unprognostic (1.65e-2)" "prognostic unfavorable (2.76e-5)" "unprognostic (2.49e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.09e-2)" "unprognostic (1.79e-1)" "unprognostic (7.90e-2)" "unprognostic (3.92e-2)" 7.4 6.2 6.4 10.0 6.1 89.9 6.4 10.3 8.4 8.1 5.0 16.3 10.6 5.7 2.3 37.6 6.0 3.0 6.9 5.6 4.9 5.6 4.8 9.0 16.9 4.8 5.2 8.1 8.9 2.6 3.6 15.3 5.2 4.9 16.5 4.9 9.5 1.5 4.1 20.1 13.0 9.4 4.9 12.5 11.7 55.0 4.2 43.0 4.3 2.3 24.9 4.8 13.7 5.6 167.9 199.9 164.8 113.6 16.8 28.7 87.5 237.8 139.3 257.2 195.3 134.6 158.5 65.5 91.4 151.9 156.9 220.9 188.8 101.2 240.6 118.7 206.4 135.6 263.5 123.5 4.1 71.4 109.0 7.7 12.8 145.8 146.9 56.6 146.4 100.5 114.0 132.4 241.1 144.4 66.9 98.5 66.6 216.4 84.9 69.7 205.1 86.3 115.3 123.6 151.2 118.9 225.4 121.9 82.7 112.3 149.1 127.1 91.2 168.2 146.0 140.5 345.1 43.5 127.7 80.0 74.5 162.0 265.3 34.4 0.6 2.9 0.6 0.1 0.4 1.1 1.3 1.3 2.4 0.5 1.2 0.4 0.4 3.0 0.3 2.6 8.0 1.0 6.4 6.1 10.3 8.4 5.6 4.9 4.8 5.2 5.2 4.9 4.2 5.6 2.5 0.0 3.1 1.3 6.8 16.6 6.6 8.0 2.2 6.4 3.4 4.3 3.2 0.0 7.6 3.7 0.0 45.5 2.8 16.5 0.0 3.2 41.5 4.5 4.0 4.7 5.4 142.9 5.0 2.9 68.3 7.2 16.3 6.8 8.9 13.2 9.3 2.1 21.5 3.3 5.2 17.0 10.2 8.7 15.0 15.4 3.7 5.2 3.6 1.9 5.5 3.8 4.1 2.0 1.7 2.3 3.2 1.9 17.5 5.9 2.0 0.1 3.2 4.6 6.6 7.4 10.9 136.4 74.2 38.0 14.2 14.6 6.8 0.4 24.1 6.7 PRICKLE4 "C6orf49, DKFZp761H221, OEBT" ENSG00000278224 "Prickle planar cell polarity protein 4" Q2TBC4 6 41780782-41787452 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 15.0;Basal squamous epithelial cells: 30.7;Erythroid cells: 17.7;Gastric mucus-secreting cells: 17.3;Plasma cells: 36.8;Squamous epithelial cells: 49.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 4.0;HeLa: 4.6;hTERT-RPE1: 9.7" "HPA031240, HPA055593" Approved Approved "Mitotic spindle,Centriolar satellite" Yes NA "Cluster 72: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 59: Non-specific - Transcription" "Centriolar satellite" "Mitotic spindle" "HPA031240: AB_10600929, HPA055593: " "unprognostic (1.16e-2)" "unprognostic (2.08e-2)" "unprognostic (2.56e-2)" "unprognostic (6.86e-2)" "unprognostic (1.58e-1)" "unprognostic (2.15e-2)" "unprognostic (6.41e-2)" "unprognostic (1.93e-2)" "unprognostic (3.47e-4)" "unprognostic (4.25e-2)" "unprognostic (2.94e-2)" "unprognostic (1.46e-1)" "unprognostic (1.56e-5)" "unprognostic (3.64e-3)" "unprognostic (5.74e-2)" "unprognostic (1.50e-1)" "unprognostic (2.17e-3)" 1.8 1.2 1.3 0.3 1.2 0.1 1.9 1.3 1.2 2.2 0.0 1.6 1.1 2.4 0.0 3.8 2.3 1.0 1.9 0.7 1.0 1.3 2.0 2.1 0.1 1.1 0.7 1.3 1.2 0.4 1.0 0.6 1.0 2.3 0.5 0.6 1.7 0.4 1.6 0.8 1.2 1.5 0.3 4.5 2.6 0.8 1.0 0.0 2.5 1.5 0.3 2.6 2.9 1.3 0.2 0.6 1.3 1.2 0.0 0.0 4.0 0.1 0.1 0.0 0.0 0.7 0.9 0.4 1.5 0.0 0.1 2.1 0.0 0.1 0.0 0.3 0.3 0.2 4.6 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 9.7 0.0 0.5 1.2 0.2 0.0 0.6 0.0 0.7 0.2 1.8 0.2 1.3 0.3 0.0 0.2 1.4 0.1 0.4 0.0 2.4 0.2 1.2 0.6 0.7 0.6 0.4 0.8 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 1.3 1.2 0.7 1.0 1.1 0.7 1.0 0.3 1.0 1.3 0.0 0.0 0.0 1.6 15.0 1.5 1.4 2.4 30.7 2.3 0.0 0.0 0.6 0.0 1.0 0.0 0.0 0.0 2.7 2.6 0.0 0.0 0.3 0.0 0.0 2.8 3.5 17.7 0.2 0.0 0.0 4.8 17.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.5 0.0 0.0 1.5 0.6 1.2 8.4 0.0 0.0 1.0 1.9 0.0 0.0 0.0 0.0 0.5 2.6 36.8 1.7 2.2 0.0 0.7 4.1 0.0 1.9 3.7 1.9 1.4 49.4 2.0 0.0 10.9 0.0 3.0 1.4 PRKACA PKACa ENSG00000072062 "Protein kinase cAMP-activated catalytic subunit alpha" P17612 19 14091688-14118084 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 310.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 116.8;Theca cells: 100.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010361, HPA071185" Approved Approved "Cytokinetic bridge,Cytosol" Yes NA 170000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 52: Non-specific - Transcription" Cytosol "Cytokinetic bridge" "CAB010361: AB_2268772, HPA071185: AB_2686356" "unprognostic (1.08e-1)" "prognostic favorable (6.28e-6)" "unprognostic (2.09e-2)" "prognostic unfavorable (6.26e-5)" "unprognostic (1.38e-2)" "unprognostic (2.95e-1)" "unprognostic (1.64e-1)" "unprognostic (9.36e-3)" "unprognostic (7.01e-2)" "unprognostic (3.41e-1)" "prognostic favorable (6.47e-4)" "unprognostic (2.86e-1)" "unprognostic (1.17e-1)" "unprognostic (4.68e-2)" "unprognostic (1.87e-1)" "unprognostic (3.66e-2)" "unprognostic (6.14e-3)" 62.7 126.5 46.6 27.6 47.6 18.9 53.9 39.9 64.2 53.2 29.5 59.0 20.9 56.9 28.5 41.8 53.7 14.2 204.8 49.2 53.3 35.4 78.4 46.1 15.9 56.8 54.5 94.1 34.0 21.6 71.2 17.3 55.3 41.2 13.0 25.2 42.3 20.8 310.9 42.3 36.3 21.8 40.7 71.6 40.2 57.2 50.3 18.2 39.6 122.1 13.4 50.6 44.2 46.6 37.5 16.3 40.3 74.4 36.2 30.8 9.9 30.5 23.6 32.7 27.5 21.6 15.0 13.8 26.2 49.2 22.9 25.4 26.7 26.6 32.3 23.1 17.7 27.7 20.6 24.4 36.8 21.9 33.5 33.8 18.1 30.0 11.1 26.6 29.7 19.0 29.1 47.3 36.7 48.1 46.3 31.9 21.5 38.7 45.0 38.0 47.8 36.7 41.7 13.5 36.5 24.2 34.2 31.3 23.8 18.1 37.2 26.5 37.7 71.7 20.3 100.7 39.6 31.9 24.9 23.6 49.6 28.0 32.7 0.1 1.5 0.2 0.8 2.7 0.3 0.8 0.3 0.5 1.1 0.5 0.5 0.7 3.2 0.4 2.5 0.6 0.3 0.6 46.6 47.6 39.9 64.2 49.2 53.3 56.8 54.5 55.3 40.7 50.3 46.6 39.5 6.4 3.4 9.4 7.0 8.8 6.8 6.4 2.2 42.2 19.2 19.0 116.8 22.8 4.7 14.7 27.1 6.9 9.0 24.6 7.9 12.4 32.4 11.7 22.9 26.7 17.5 2.5 16.9 19.1 5.7 22.6 8.6 12.9 0.0 15.9 26.4 39.7 34.5 3.3 21.6 11.8 2.0 49.4 50.8 15.7 49.0 37.1 14.2 9.4 37.8 26.1 9.2 10.1 10.7 15.6 11.6 51.9 3.3 6.4 20.7 11.8 7.0 23.9 19.7 23.3 23.5 26.4 6.9 10.1 11.2 8.1 10.0 100.6 14.4 6.6 PRKACB PKACb ENSG00000142875 "Protein kinase cAMP-activated catalytic subunit beta" P22694 1 84078062-84238498 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 334.4;Inhibitory neurons: 348.8;Oligodendrocyte precursor cells: 302.6;Oligodendrocytes: 499.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010363, HPA029754, HPA071185" Approved Approved "Cytokinetic bridge,Cytosol" Yes NA 130000 "Cluster 48: NK-cells - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Cytokinetic bridge" "CAB010363: AB_2170182, HPA029754: AB_10601491, HPA071185: AB_2686356" "unprognostic (9.38e-2)" "unprognostic (1.18e-1)" "unprognostic (6.37e-2)" "unprognostic (1.39e-1)" "unprognostic (1.58e-1)" "unprognostic (1.98e-1)" "prognostic unfavorable (9.49e-4)" "unprognostic (1.28e-1)" "unprognostic (3.28e-2)" "unprognostic (1.92e-1)" "unprognostic (2.31e-1)" "unprognostic (4.62e-2)" "prognostic favorable (1.89e-6)" "unprognostic (1.22e-1)" "unprognostic (3.28e-1)" "unprognostic (1.12e-2)" "unprognostic (2.48e-1)" 16.5 47.7 79.4 26.1 101.6 16.0 17.7 70.0 113.3 19.8 0.0 55.9 10.8 19.2 38.8 17.8 10.0 26.2 23.8 100.7 107.5 23.8 20.8 15.8 41.8 53.5 44.4 17.8 27.8 23.5 24.7 11.5 65.4 30.6 51.7 71.6 83.7 27.3 4.9 4.1 12.7 28.8 59.9 36.0 34.1 8.1 91.0 63.5 25.2 13.5 36.8 27.6 7.7 110.0 8.6 16.9 26.4 31.8 29.9 26.1 12.3 41.7 31.4 20.8 19.4 0.4 7.5 45.1 28.0 32.8 38.0 5.8 12.6 13.6 22.0 44.1 6.8 99.3 21.3 3.2 29.4 39.8 2.2 15.6 6.0 20.2 11.2 30.2 97.2 16.7 3.2 25.2 34.3 1.6 51.8 21.0 26.1 0.1 11.8 39.6 41.2 27.3 50.5 30.2 8.6 33.4 23.0 8.8 25.6 19.7 8.1 8.2 86.8 28.7 22.4 29.4 31.9 18.6 24.2 45.3 13.7 41.5 36.5 56.3 7.5 16.4 59.3 10.2 47.7 35.2 43.4 52.9 19.4 28.4 65.0 69.5 3.8 73.1 16.2 11.1 44.2 66.8 79.4 101.6 70.0 113.3 100.7 107.5 53.5 44.4 65.4 59.9 91.0 110.0 9.5 0.0 1.5 118.8 56.6 5.1 7.2 3.5 11.4 44.9 11.5 9.1 44.4 21.5 5.2 14.7 35.5 1.9 103.0 115.5 33.2 6.2 2.9 11.4 27.0 13.4 21.7 52.3 334.4 11.9 1.2 17.0 16.3 14.0 58.9 15.2 28.5 17.0 27.1 47.1 348.8 58.1 4.1 62.3 24.4 3.6 14.9 51.6 16.0 95.5 14.6 35.6 96.8 302.6 499.0 20.6 42.2 21.8 53.9 10.0 4.5 25.6 6.3 34.4 13.1 14.1 20.3 13.9 8.0 8.1 2.8 0.7 87.6 11.4 51.1 9.1 PRKACG PKACg ENSG00000165059 "Protein kinase cAMP-activated catalytic subunit gamma" P22612 9 69012504-69014113 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 152 "testis: 24.6" "Group enriched" "Detected in some" 27 "Early spermatids: 71.0;Late spermatids: 88.4;Spermatocytes: 41.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004530, HPA071185" Supported Uncertain "Cytokinetic bridge,Cytosol" Yes NA "Cluster 74: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "Cytokinetic bridge" "CAB004530: AB_628137, HPA071185: AB_2686356" "unprognostic (2.74e-1)" "unprognostic (3.61e-2)" "unprognostic (7.22e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.3 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 PRKCI "DXS1179E, PKCI" ENSG00000163558 "Protein kinase C iota" P41743 3 170222424-170305977 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026574, HPA038635" Approved Supported "Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 46: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Cytosol "Microtubules, Cytokinetic bridge" "HPA026574: AB_1855428, HPA038635: AB_2676124" "unprognostic (2.26e-1)" "unprognostic (6.75e-2)" "unprognostic (4.57e-2)" "prognostic unfavorable (3.93e-6)" "unprognostic (1.59e-1)" "unprognostic (1.84e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (2.52e-1)" "unprognostic (7.10e-2)" "unprognostic (1.73e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (5.32e-3)" "prognostic favorable (3.10e-4)" "unprognostic (1.16e-1)" "unprognostic (2.65e-1)" "unprognostic (1.06e-1)" "unprognostic (9.73e-2)" 6.7 5.0 2.0 6.9 2.4 2.6 10.4 2.0 3.2 12.7 0.3 12.4 11.6 11.0 8.2 15.1 15.9 11.4 6.9 3.4 1.1 13.5 7.3 16.6 4.6 0.4 0.2 13.6 7.0 13.0 3.1 10.9 0.5 17.3 13.1 6.2 17.5 12.7 6.2 6.9 10.8 11.0 0.2 5.2 34.5 12.5 0.9 10.9 24.5 9.8 10.4 16.1 6.2 1.1 81.6 20.2 20.0 21.6 17.3 23.9 32.2 20.4 29.9 26.4 28.3 29.7 38.6 24.7 65.3 28.8 36.4 37.3 37.9 40.0 44.8 18.2 23.5 22.9 24.3 16.6 27.9 20.9 10.0 21.8 27.5 22.6 35.1 42.8 20.9 13.3 25.8 19.8 27.4 28.0 30.5 8.5 42.3 86.4 22.1 21.8 30.7 41.2 42.3 24.4 31.5 25.8 44.1 57.7 20.0 29.5 63.0 14.5 22.4 27.5 21.1 26.0 34.3 33.9 34.9 35.2 19.8 16.4 11.0 0.0 0.6 0.4 1.1 0.6 1.7 0.9 1.5 2.0 0.8 1.2 1.6 0.9 0.3 2.6 0.5 0.8 1.1 0.7 2.0 2.4 2.0 3.2 3.4 1.1 0.4 0.2 0.5 0.2 0.9 1.1 17.6 73.7 82.1 23.2 5.8 57.1 49.5 39.8 30.7 16.4 29.0 19.7 16.2 24.3 45.3 49.7 14.6 30.2 15.0 29.0 25.4 16.5 8.4 42.0 29.7 20.5 29.3 10.5 77.2 22.0 26.6 32.2 59.7 72.3 8.8 20.4 17.5 17.7 10.0 15.2 55.2 28.3 50.8 18.6 26.8 6.8 23.3 11.6 17.8 22.5 12.7 8.8 6.2 33.2 33.5 55.2 18.6 28.6 29.4 99.4 18.7 20.4 31.9 9.4 19.7 23.7 18.7 15.8 20.6 38.5 63.6 20.7 14.8 14.3 28.5 80.1 PRR11 FLJ11029 ENSG00000068489 "Proline rich 11" Q96HE9 17 59155732-59206709 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.1;lymphoid tissue: 20.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 26.3;Extravillous trophoblasts: 22.3;Granulosa cells: 14.4;Kupffer cells: 18.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 9.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA023923, HPA052376" Uncertain Approved "Endoplasmic reticulum" Yes Yes "Cluster 14: Monocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Endoplasmic reticulum" "HPA023923: AB_1855783, HPA052376: AB_2681803" "unprognostic (1.74e-2)" "unprognostic (1.02e-1)" "unprognostic (1.30e-2)" "prognostic unfavorable (1.90e-4)" "unprognostic (2.15e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.35e-7)" "prognostic unfavorable (1.79e-4)" "unprognostic (7.22e-3)" "unprognostic (2.00e-2)" "prognostic unfavorable (6.18e-4)" "unprognostic (2.80e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.56e-2)" "unprognostic (5.21e-2)" "unprognostic (1.84e-1)" "unprognostic (1.55e-3)" 1.3 0.7 1.8 6.5 2.0 18.1 1.8 4.3 2.7 1.2 1.1 4.6 6.5 1.7 0.5 3.8 1.4 1.4 1.0 2.0 1.3 0.6 1.4 2.3 10.3 2.3 1.5 1.4 0.5 0.3 0.0 4.3 2.2 0.8 5.6 1.7 0.6 0.7 1.2 3.1 5.0 3.6 1.1 3.3 2.4 1.8 2.3 20.6 1.3 0.4 12.0 2.0 0.6 3.7 105.3 56.9 84.5 24.8 2.4 16.0 31.7 66.7 41.9 69.1 54.2 68.4 78.7 80.2 65.9 52.7 56.2 40.7 67.0 73.9 145.0 99.3 39.1 86.4 58.8 50.3 0.6 88.7 32.5 4.0 5.3 81.9 109.0 17.1 77.2 57.9 48.6 76.7 72.8 95.2 80.7 26.1 31.9 52.0 82.5 67.3 135.7 45.9 20.0 32.4 34.5 45.4 61.7 18.4 29.2 38.0 54.4 34.1 57.8 146.4 157.3 73.5 117.8 48.8 108.2 73.6 34.5 47.4 150.1 1.7 2.1 2.3 0.6 4.0 0.2 1.1 0.5 0.7 2.6 0.6 0.3 0.5 2.1 0.5 9.5 1.1 1.4 0.8 1.8 2.0 4.3 2.7 2.0 1.3 2.3 1.5 2.2 1.1 2.3 3.7 4.5 0.0 1.7 3.3 3.1 1.9 2.0 1.5 0.0 2.0 0.8 1.5 2.0 1.5 1.6 0.0 0.0 6.2 1.4 2.0 0.0 0.4 0.9 1.4 1.9 3.6 4.9 26.3 1.6 0.5 22.3 2.9 2.6 2.2 2.5 14.4 4.2 0.3 7.8 1.7 1.8 5.0 0.0 18.6 6.3 0.4 0.9 7.8 1.8 2.8 8.4 0.9 4.1 2.0 3.4 0.9 0.7 2.2 9.7 1.1 0.5 0.5 0.6 3.2 0.0 2.9 3.3 2.6 5.1 5.5 1.3 2.1 3.3 1.3 8.4 1.7 PRR16 DSC54 ENSG00000184838 "Proline rich 16" Q569H4 5 120464300-120687332 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 30.4" "Group enriched" "Detected in many" 9 "Excitatory neurons: 171.6;Inhibitory neurons: 188.9" "Cancer enriched" "Detected in many" 5 "prostate cancer: 13.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 77.3;BJ hTERT+: 83.9;fHDF/TERT166: 102.1;HSkMC: 62.5;hTERT-RPE1: 103.0;LHCN-M2: 97.9;U-138 MG: 117.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049254 Approved Approved Nucleoplasm,Midbody,Cytosol Yes No "Cluster 25: Monocytes - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Midbody, Cytosol" "HPA049254: AB_2680693" "unprognostic (1.71e-1)" "unprognostic (3.87e-2)" "unprognostic (3.45e-1)" "unprognostic (1.20e-1)" "unprognostic (6.61e-2)" "unprognostic (7.07e-2)" "unprognostic (1.53e-1)" "unprognostic (2.42e-2)" "unprognostic (8.33e-2)" "unprognostic (4.40e-2)" "unprognostic (2.76e-2)" "unprognostic (2.06e-1)" "unprognostic (2.54e-8)" "unprognostic (3.05e-2)" "unprognostic (9.13e-2)" "unprognostic (2.65e-1)" "unprognostic (2.38e-3)" 11.0 2.8 2.0 5.2 2.1 0.2 7.9 6.1 3.5 14.9 0.0 5.1 1.7 11.8 1.5 1.8 7.0 5.7 12.7 2.2 5.1 3.0 0.9 9.8 1.1 3.4 1.8 5.6 2.0 1.1 1.7 9.7 3.2 9.3 4.5 7.0 2.6 2.4 26.4 4.0 5.0 8.2 0.7 2.5 4.0 2.4 2.3 0.7 4.4 30.4 0.9 9.5 10.0 1.4 3.7 0.0 8.0 0.0 22.2 77.3 0.0 37.0 83.9 51.5 39.1 0.0 0.2 0.0 0.0 102.1 9.3 0.0 8.1 0.9 53.8 0.0 1.9 0.0 1.2 0.0 21.5 0.2 0.1 62.5 8.9 15.4 48.0 103.0 1.7 0.0 0.1 0.1 97.9 0.0 0.0 0.0 0.9 0.0 1.4 0.0 6.2 0.0 4.3 0.0 0.3 16.1 0.1 0.0 1.1 6.1 0.1 0.1 0.5 117.9 13.3 3.8 19.4 0.3 0.0 0.0 6.7 0.2 4.1 0.1 0.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.3 2.0 2.1 6.1 3.5 2.2 5.1 3.4 1.8 3.2 0.7 2.3 1.4 1.4 0.0 0.0 14.0 0.4 1.3 6.2 0.0 0.0 7.5 1.5 1.9 3.2 0.0 0.0 0.0 14.6 0.1 0.1 0.0 0.0 0.1 16.8 0.9 18.9 0.8 0.0 0.0 171.6 0.0 0.0 13.5 0.0 0.8 0.0 0.2 0.4 0.0 0.5 15.2 188.9 0.0 0.0 1.8 2.7 11.6 2.8 1.0 1.8 9.4 0.1 2.6 0.0 7.5 3.9 0.2 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.7 0.0 1.4 9.6 0.9 1.4 0.5 0.6 0.5 0.4 3.1 0.0 0.7 PRR19 MGC70924 ENSG00000188368 "Proline rich 19" A6NJB7 19 42302098-42310814 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 21.6" "Group enriched" "Detected in some" 9 "Early spermatids: 26.7;Late spermatids: 60.1;Spermatocytes: 37.9;Spermatogonia: 22.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA070350 Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies,Mitotic chromosome,Mitochondria" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoli, Nucleoli rim, Mitotic chromosome" "Nucleoplasm, Nuclear bodies, Mitochondria" "HPA070350: AB_2686259" "unprognostic (2.05e-1)" "unprognostic (8.03e-3)" "unprognostic (4.02e-2)" "unprognostic (7.55e-3)" "unprognostic (7.33e-2)" "unprognostic (1.08e-2)" "unprognostic (2.44e-5)" "unprognostic (3.57e-1)" "unprognostic (1.92e-2)" "unprognostic (8.10e-3)" "unprognostic (3.85e-2)" "unprognostic (2.77e-1)" "unprognostic (2.87e-3)" "unprognostic (4.21e-1)" "unprognostic (7.26e-2)" "unprognostic (1.78e-1)" "unprognostic (4.36e-2)" 0.4 1.1 1.9 0.7 2.5 2.3 0.5 2.1 2.4 0.7 1.3 0.4 0.4 0.6 0.4 1.1 0.5 0.5 0.2 1.9 1.7 0.7 0.6 0.3 0.5 1.8 1.5 0.5 0.4 0.4 0.9 0.4 1.9 0.7 0.2 0.5 0.7 0.4 0.3 0.7 0.5 0.3 1.4 0.5 0.4 21.6 2.0 0.6 0.4 0.1 0.5 0.4 0.7 2.0 2.7 3.9 2.2 2.9 0.1 0.2 2.2 1.2 1.2 3.5 3.5 1.6 2.5 0.5 4.5 1.3 2.6 0.8 1.0 1.0 0.7 1.8 1.0 2.8 2.0 1.0 0.8 0.7 1.6 1.1 1.6 2.3 0.4 0.7 0.6 2.9 1.5 1.3 1.6 6.2 2.7 1.3 2.3 2.5 0.0 1.0 0.4 0.2 1.1 2.1 4.9 1.9 2.1 1.5 0.6 0.6 2.0 1.0 0.8 2.3 3.4 0.5 2.1 0.2 1.0 0.8 2.4 2.0 2.4 0.4 0.4 0.1 0.4 0.4 0.1 0.6 0.3 0.5 0.5 0.4 0.4 0.2 0.4 0.5 0.1 0.3 0.5 0.2 1.9 2.5 2.1 2.4 1.9 1.7 1.8 1.5 1.9 1.4 2.0 2.0 1.2 0.0 0.5 0.0 0.7 0.6 0.9 1.9 4.0 0.4 2.7 2.8 0.5 0.0 0.6 0.0 0.0 0.9 0.3 0.8 1.9 0.9 26.7 1.0 0.7 1.2 0.0 0.0 0.4 1.2 0.6 0.6 1.1 1.5 0.0 0.3 0.0 0.4 0.8 1.7 0.4 0.1 0.0 0.0 0.3 60.1 1.2 0.4 0.0 1.0 0.1 0.0 1.0 1.0 0.3 0.4 1.2 1.2 0.6 0.4 0.6 0.6 2.3 0.2 0.0 0.8 0.7 37.9 22.5 2.1 0.9 0.5 0.4 0.6 0.4 0.7 PRR23A ENSG00000206260 "Proline rich 23A" A6NEV1 3 139003962-139006268 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "testis: 1.5" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 17 "testis cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047473 Uncertain Approved "Nucleoplasm,Nuclear bodies,Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 78: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Microtubules" "Nuclear bodies, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA047473: AB_2680062" "unprognostic (1.48e-1)" 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.6 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.2 0.1 0.0 0.2 0.1 0.2 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRR23B FLJ46116 ENSG00000184814 "Proline rich 23B" Q6ZRT6 3 139019031-139020926 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "testis: 1.3" "Group enriched" "Detected in some" 8 "Spermatocytes: 6.4;Spermatogonia: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047473 Uncertain Uncertain "Nucleoplasm,Nuclear bodies,Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 83: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Microtubules" "Nuclear bodies, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA047473: AB_2680062" "unprognostic (7.57e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.4 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 PRR23C FLJ46210 ENSG00000233701 "Proline rich 23C" Q6ZRP0 3 139042102-139044892 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 3.5;Late spermatids: 2.0;Spermatocytes: 1.6;Spermatogonia: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.2" "Not detected" "Not detected" HPA047473 Uncertain Approved "Nucleoplasm,Nuclear bodies,Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 17: Basophils - Unknown function" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoplasm, Microtubules" "Nuclear bodies, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA047473: AB_2680062" "unprognostic (1.00e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.3 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 3.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 PRR35 C16orf11 ENSG00000161992 "Proline rich 35" P0CG20 16 560394-565529 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "brain: 46.5;kidney: 17.2" "Cell type enriched" "Detected in some" 9 "Collecting duct cells: 36.8" "Not detected" "Not detected" "Region enriched" "Detected in many" 20 "cerebellum: 46.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 4.5" "Not detected" "Not detected" HPA069297 Uncertain Approved "Nucleoli,Cytokinetic bridge,Cytosol" Yes NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoli "Cytokinetic bridge, Cytosol" "HPA069297: AB_2686113" "unprognostic (6.96e-2)" "unprognostic (3.08e-2)" "unprognostic (5.25e-1)" "unprognostic (8.11e-2)" "unprognostic (2.56e-1)" "unprognostic (3.38e-2)" "unprognostic (1.17e-1)" 0.0 0.1 0.1 0.0 0.2 0.0 0.0 46.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 17.2 0.0 0.0 0.0 0.2 1.5 0.0 1.1 0.0 0.0 0.0 2.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 46.5 1.8 0.3 0.1 0.2 1.5 2.3 0.3 0.4 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.9 0.1 0.0 1.3 0.0 0.0 36.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRR36 ENSG00000183248 "Proline rich 36" Q9H6K5 19 7868719-7874390 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 21.0;pituitary gland: 29.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 13.4;Breast glandular cells: 9.2;Cone photoreceptor cells: 12.5;Horizontal cells: 10.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 21.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 28.7;SCLC-21H: 8.0;SH-SY5Y: 17.9;T-47d: 9.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062741 Uncertain Approved "Nucleoplasm,Nuclear speckles,Golgi apparatus" Yes No "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 14: REH - Unknown function" "Cluster 35: Glandular cells - Unknown function" "Golgi apparatus" "Nucleoplasm, Nuclear speckles" "HPA062741: AB_2684860" "unprognostic (3.15e-2)" "unprognostic (1.02e-1)" "unprognostic (6.23e-2)" "unprognostic (5.61e-2)" "unprognostic (1.72e-1)" "unprognostic (1.20e-2)" "unprognostic (9.62e-2)" "unprognostic (3.46e-3)" "unprognostic (1.18e-1)" "unprognostic (1.15e-3)" "unprognostic (1.75e-2)" "unprognostic (2.99e-1)" "unprognostic (5.69e-3)" "unprognostic (7.89e-2)" "prognostic favorable (7.74e-4)" "unprognostic (3.56e-1)" "unprognostic (8.52e-3)" 0.1 0.9 3.5 0.1 4.0 0.0 2.5 3.0 21.0 0.8 0.0 0.3 0.2 0.6 0.3 0.3 1.2 0.1 0.2 7.5 0.0 3.3 0.2 0.9 0.0 0.0 0.0 0.7 2.8 2.0 29.6 0.0 0.0 2.5 0.0 5.0 4.1 0.3 0.0 0.7 0.2 0.0 0.0 0.1 0.8 0.8 0.0 0.0 1.1 0.0 0.0 0.3 0.3 0.0 0.1 0.9 6.6 5.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.4 2.9 0.0 1.9 0.0 0.6 0.1 5.1 0.0 0.0 0.0 6.4 0.0 0.3 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 3.2 0.1 0.1 0.0 3.0 0.3 0.3 2.5 0.4 0.6 28.7 0.0 0.3 3.7 5.4 8.0 17.9 0.0 0.3 0.0 0.5 9.1 0.0 0.0 0.0 3.2 0.1 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 4.0 3.0 21.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.0 0.5 0.0 0.8 0.0 2.2 13.4 9.2 7.7 1.3 2.8 0.0 5.5 12.5 0.2 0.2 0.2 5.9 3.0 5.4 4.5 0.7 0.2 3.6 0.0 6.9 0.9 0.4 0.3 2.6 6.7 0.0 1.1 0.0 0.5 0.1 10.1 5.8 0.7 0.0 0.0 0.0 0.7 0.6 0.4 0.0 3.7 0.0 5.4 0.0 4.5 0.8 0.9 0.1 0.0 0.6 1.3 0.1 1.5 0.0 4.5 0.0 0.3 1.1 0.3 3.7 3.1 0.0 0.3 0.3 0.5 0.3 1.0 PRR5L "FLJ14213, PROTOR-2" ENSG00000135362 "Proline rich 5 like" Q6MZQ0 11 36296288-36465204 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 46.9;intestine: 34.7;lymphoid tissue: 36.4" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 302.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HeLa: 35.5;HMC-1: 55.7;hTERT-HME1: 57.9;SiHa: 40.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070174 Approved "Cytokinetic bridge,Cytosol" Yes No "Cluster 38: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Cytokinetic bridge, Cytosol" "HPA070174: AB_2686231" "unprognostic (6.76e-2)" "unprognostic (1.61e-1)" "unprognostic (3.48e-2)" "prognostic favorable (7.30e-5)" "unprognostic (2.34e-2)" "unprognostic (1.21e-1)" "unprognostic (1.63e-1)" "unprognostic (7.45e-2)" "unprognostic (3.61e-1)" "unprognostic (1.46e-2)" "unprognostic (3.03e-3)" "unprognostic (2.12e-1)" "prognostic unfavorable (7.71e-8)" "prognostic unfavorable (4.86e-4)" "unprognostic (1.66e-1)" "unprognostic (1.44e-1)" "unprognostic (2.98e-2)" 3.6 1.5 10.1 8.9 27.8 4.7 2.7 21.7 16.7 11.4 2.2 34.7 3.3 2.8 2.0 1.4 6.3 7.1 2.0 9.6 21.1 7.7 2.9 13.6 9.3 36.6 23.8 12.8 1.2 0.9 2.7 3.6 33.9 2.4 27.8 0.7 7.8 2.0 0.9 1.7 12.2 5.9 24.1 36.4 3.4 1.5 23.9 3.4 3.2 0.7 3.3 4.3 3.8 46.9 0.0 5.5 10.3 0.2 1.4 0.0 0.1 13.2 8.9 25.7 27.2 0.0 0.2 0.1 4.4 15.7 5.9 0.5 2.1 5.9 12.9 5.0 3.7 1.5 35.5 0.0 3.5 0.0 55.7 3.8 9.0 2.3 57.9 25.2 9.4 0.0 0.0 0.1 13.6 3.3 0.7 0.1 0.8 0.1 2.3 4.1 1.1 1.1 27.0 6.9 0.0 0.4 40.1 0.0 2.2 6.5 0.0 0.6 7.8 22.3 6.8 0.0 16.4 0.2 0.0 0.0 9.7 1.5 6.7 36.1 2.0 24.9 34.6 21.4 8.2 0.0 12.2 29.7 2.5 1.6 2.6 18.0 11.8 9.6 24.6 7.7 0.0 15.4 10.1 27.8 21.7 16.7 9.6 21.1 36.6 23.8 33.9 24.1 23.9 46.9 2.1 19.2 4.2 17.6 0.7 0.4 0.2 5.0 0.0 0.1 1.9 0.9 0.9 1.5 6.8 7.3 0.0 0.2 25.9 44.3 1.9 1.3 17.6 1.5 0.8 7.7 1.8 7.0 1.8 2.2 0.1 2.1 1.1 2.5 5.1 0.5 22.5 0.4 8.8 0.0 1.1 22.7 10.2 11.7 0.7 54.9 0.6 5.4 0.0 16.9 4.7 1.2 58.7 31.7 302.0 3.9 37.0 0.4 4.2 0.7 13.2 0.5 9.0 0.2 6.6 1.8 2.6 0.3 0.6 0.4 0.6 0.3 14.5 0.9 17.5 0.5 PSD3 "DKFZp761K1423, EFA6D, EFA6R, HCA67, KIAA0942" ENSG00000156011 "Pleckstrin and Sec7 domain containing 3" Q9NYI0 8 18527303-19084730 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 62.4" "Cell type enhanced" "Detected in many" "Astrocytes: 558.3;Early spermatids: 686.7;Excitatory neurons: 284.7;Oligodendrocyte precursor cells: 488.1;Oligodendrocytes: 584.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 53.8;hTERT-RPE1: 48.0;LHCN-M2: 47.3;U-87 MG: 49.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002455 Enhanced Approved Nucleoplasm,Vesicles,Cytosol Yes No "Cluster 11: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Vesicles" Cytosol "HPA002455: AB_2666597" "unprognostic (3.87e-2)" "unprognostic (2.52e-2)" "prognostic favorable (7.55e-4)" "prognostic unfavorable (5.76e-5)" "unprognostic (2.56e-1)" "unprognostic (2.66e-2)" "unprognostic (1.04e-2)" "unprognostic (8.84e-2)" "unprognostic (7.27e-2)" "unprognostic (3.39e-1)" "unprognostic (2.50e-3)" "unprognostic (2.13e-1)" "unprognostic (7.18e-3)" "unprognostic (3.71e-2)" "unprognostic (8.77e-2)" "unprognostic (3.83e-2)" "unprognostic (1.45e-1)" 2.4 17.8 24.8 3.1 46.2 1.2 5.9 62.4 46.1 11.9 0.0 6.7 4.8 8.8 3.8 5.3 2.5 7.4 27.5 51.9 4.0 1.9 18.9 4.6 2.5 3.3 10.0 18.0 9.9 18.4 7.3 6.6 1.8 3.9 7.3 19.9 4.1 5.8 1.3 4.4 5.0 5.8 0.0 10.4 9.8 16.4 7.8 2.2 6.1 2.3 3.4 5.8 4.3 17.2 11.0 5.7 25.0 0.1 8.8 53.8 1.3 5.7 8.9 5.1 10.5 3.3 4.3 6.5 3.6 23.8 22.3 0.9 7.3 10.1 9.7 0.0 6.6 0.6 4.6 0.5 15.9 0.2 0.4 14.2 6.2 28.2 4.9 48.0 6.8 1.6 0.8 4.9 47.3 3.7 0.0 1.2 4.9 9.6 14.7 5.2 21.4 3.0 12.7 14.0 10.7 11.8 2.5 1.1 3.8 5.4 0.3 2.6 28.0 15.7 10.8 37.5 5.1 0.4 0.7 14.8 49.5 2.7 5.4 0.7 0.2 0.2 0.1 0.1 0.2 0.3 0.2 0.1 0.1 0.5 0.1 0.1 0.3 0.3 0.2 0.1 0.4 0.1 24.8 46.2 62.4 46.1 51.9 4.0 3.3 10.0 1.8 0.0 7.8 17.2 8.1 3.2 2.7 558.3 3.3 21.9 13.7 26.4 13.6 191.9 14.4 10.7 119.2 7.2 23.9 9.2 118.9 3.2 0.1 48.5 1.9 13.5 686.7 12.5 69.9 8.2 6.1 0.0 284.7 8.7 1.7 44.3 43.8 6.6 0.0 87.2 4.2 42.9 13.1 18.5 121.6 20.0 44.7 16.0 25.9 217.9 33.2 9.0 1.8 148.9 59.7 78.0 0.0 488.1 584.6 27.0 13.5 53.8 0.1 11.2 20.3 0.3 41.0 52.0 13.1 29.3 17.7 16.5 17.7 32.4 9.9 1.1 1.1 114.9 17.2 23.7 PSEN1 "AD3, FAD, PS1, S182" ENSG00000080815 "Presenilin 1" P49768 14 73136418-73223691 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Cell adhesion, Notch signaling pathway" "Hydrolase, Protease" "Alzheimer disease, Amyloidosis, Cancer-related genes, Cardiomyopathy, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Oligodendrocytes: 395.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006844, HPA030760, HPA067496" Approved Supported "Nucleoplasm,Golgi apparatus,Cell Junctions" Yes No "Cluster 31: Non-specific - Inflammatory response" "Cluster 45: Intestine - Brush border" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" "Nucleoplasm, Cell Junctions" "CAB006844: , HPA030760: AB_10696211, HPA067496: AB_2685853" "unprognostic (1.67e-1)" "unprognostic (4.79e-2)" "unprognostic (7.39e-2)" "unprognostic (8.68e-3)" "unprognostic (3.84e-1)" "unprognostic (5.48e-3)" "prognostic unfavorable (1.99e-5)" "unprognostic (1.65e-1)" "unprognostic (8.99e-2)" "unprognostic (8.45e-2)" "unprognostic (1.76e-3)" "unprognostic (2.74e-1)" "prognostic favorable (1.52e-8)" "unprognostic (2.29e-1)" "unprognostic (2.32e-1)" "unprognostic (7.12e-3)" "unprognostic (1.85e-1)" 25.1 22.6 44.3 26.5 80.7 39.6 28.2 62.4 56.0 28.1 48.9 49.5 50.2 25.3 26.9 35.2 22.9 31.7 18.0 47.4 51.6 35.5 31.9 32.1 22.4 73.0 63.8 22.0 22.9 35.1 11.6 43.1 71.5 24.3 46.3 23.4 22.9 23.4 18.4 38.2 49.0 27.1 55.7 22.6 31.0 32.5 60.8 26.2 36.9 23.3 30.7 35.0 19.2 119.1 37.1 55.9 50.6 20.0 68.9 49.9 46.7 52.5 60.1 52.6 66.7 69.9 88.9 23.7 34.1 50.5 43.0 94.9 43.2 40.1 57.3 54.6 26.7 27.1 35.1 34.4 63.8 27.7 50.7 50.4 71.9 44.3 54.4 48.5 43.2 26.2 31.0 46.6 50.0 72.8 21.0 35.7 22.0 64.5 40.4 26.4 42.7 30.2 73.7 76.5 28.1 38.3 57.4 53.0 47.1 45.4 66.3 60.7 45.7 53.1 43.5 44.1 25.3 30.3 47.9 23.7 44.9 32.8 33.3 126.8 94.5 96.3 23.1 106.0 22.6 23.1 22.3 19.0 83.4 31.8 20.7 20.1 129.3 42.8 125.0 43.6 37.0 70.3 44.3 80.7 62.4 56.0 47.4 51.6 73.0 63.8 71.5 55.7 60.8 119.1 22.2 28.9 30.5 35.9 25.8 28.6 24.6 24.7 12.0 17.1 25.0 17.7 12.5 15.7 30.2 23.9 39.6 27.1 30.7 79.1 5.9 27.1 22.9 26.3 26.4 22.3 16.2 12.0 38.9 26.7 29.2 23.7 32.1 47.4 18.3 29.6 15.7 24.6 30.5 13.5 40.2 39.5 24.4 50.5 40.8 12.9 16.4 52.3 16.0 39.4 51.8 13.8 14.4 48.7 395.8 38.2 58.8 15.4 23.6 38.8 76.2 13.0 29.0 28.0 26.3 20.0 19.0 40.2 14.4 20.4 33.0 49.9 21.6 18.6 41.3 51.5 PSMB8 "beta5i, D6S216E, LMP7, PSMB5i, RING10" ENSG00000204264 "Proteasome 20S subunit beta 8" P28062 6 32840717-32844679 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Immunity" "Hydrolase, Protease, Threonine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046995, HPA050327" Enhanced Approved "Vesicles,Cytokinetic bridge" Yes No 2700000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Cytokinetic bridge" "HPA046995: AB_2679896, HPA050327: AB_2681088" "prognostic favorable (5.08e-4)" "unprognostic (4.22e-2)" "unprognostic (2.39e-2)" "prognostic favorable (7.16e-4)" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (7.78e-2)" "unprognostic (1.09e-1)" "unprognostic (5.71e-2)" "unprognostic (1.17e-2)" "unprognostic (2.79e-2)" "unprognostic (1.47e-1)" "unprognostic (4.14e-2)" "unprognostic (1.24e-1)" "unprognostic (4.35e-2)" "unprognostic (1.97e-3)" "unprognostic (7.11e-3)" 62.7 76.9 3.3 11.2 3.4 9.8 56.5 3.3 7.3 42.7 3.4 79.9 12.9 41.3 3.2 59.5 41.6 5.8 34.2 3.4 3.5 63.7 99.2 78.2 18.2 4.3 3.4 32.1 29.5 8.2 26.6 4.4 3.7 45.2 20.4 0.7 44.2 6.4 14.4 58.0 93.9 8.9 4.0 150.4 57.0 5.9 3.6 13.5 40.8 0.1 17.2 41.3 48.1 4.1 15.1 3.9 0.3 0.0 5.1 13.1 11.2 4.9 22.9 29.1 39.3 0.0 20.9 45.7 9.4 10.5 25.5 8.1 6.8 16.6 8.0 19.2 0.0 27.6 5.9 0.3 30.3 5.2 7.5 14.9 10.3 12.9 6.8 1.9 18.1 11.8 1.1 8.1 6.1 0.1 12.9 11.7 0.1 0.0 7.3 29.3 1.3 24.1 21.3 4.9 0.8 0.2 8.6 10.4 8.5 0.1 7.0 41.0 4.3 8.8 7.6 7.8 0.6 21.0 15.9 11.2 2.2 27.7 9.0 56.8 70.3 94.6 58.1 88.0 51.2 73.4 49.1 61.1 67.5 71.1 34.8 49.6 90.2 63.0 78.2 58.5 81.2 156.0 3.3 3.4 3.3 7.3 3.4 3.5 4.3 3.4 3.7 4.0 3.6 4.1 237.0 38.5 55.8 2.9 162.0 84.4 64.1 183.7 54.7 1.8 85.3 92.5 8.7 71.4 103.2 62.5 0.0 2.7 211.2 219.9 86.1 219.4 0.6 63.2 74.9 158.5 65.7 45.0 0.1 247.6 18.3 60.7 93.8 81.5 50.7 51.4 114.5 75.0 165.9 6.7 0.5 243.8 120.1 143.5 94.9 1.9 39.1 128.2 56.9 10.3 214.3 39.9 279.1 3.0 0.7 179.6 287.9 30.5 153.2 100.1 319.8 78.9 103.2 3.0 39.5 33.2 56.8 0.4 1.2 60.5 79.6 2.7 181.6 110.9 222.6 121.6 PTPN23 "DKFZP564F0923, HD-PTP, KIAA1471" ENSG00000076201 "Protein tyrosine phosphatase non-receptor type 23" Q9H3S7 3 47381011-47413435 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Hydrolase, Protein phosphatase" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016845 Approved Supported "Nucleoplasm,Nuclear bodies,Vesicles" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nuclear bodies" Vesicles "HPA016845: AB_1855926" "unprognostic (1.17e-3)" "unprognostic (8.68e-2)" "unprognostic (2.56e-1)" "unprognostic (1.26e-1)" "unprognostic (1.63e-1)" "unprognostic (6.24e-2)" "unprognostic (1.07e-3)" "unprognostic (2.07e-2)" "unprognostic (9.55e-2)" "unprognostic (7.12e-2)" "unprognostic (5.67e-2)" "unprognostic (4.34e-2)" "prognostic favorable (1.82e-4)" "unprognostic (3.05e-2)" "unprognostic (4.40e-1)" "unprognostic (9.53e-2)" "unprognostic (4.68e-2)" 18.5 19.1 6.2 12.6 9.2 14.7 17.4 5.8 10.5 23.3 5.1 16.3 14.3 20.9 7.5 19.0 19.2 8.4 13.2 7.1 7.2 17.5 14.0 18.7 9.1 8.8 7.2 23.5 20.2 23.5 30.9 11.6 8.5 18.7 6.5 8.5 20.0 11.4 30.0 26.4 18.4 8.8 5.5 20.0 16.1 15.6 7.7 8.0 27.1 8.9 7.3 18.5 20.4 14.4 21.5 29.9 16.4 21.4 21.0 16.0 15.8 19.2 18.9 17.5 14.8 25.0 20.7 15.1 17.2 21.9 31.2 19.0 14.3 20.8 8.5 14.3 15.1 21.0 22.2 24.0 23.0 12.3 27.5 21.4 20.9 22.9 23.2 12.4 21.7 12.5 15.9 20.3 19.0 30.2 11.5 10.4 17.5 14.9 20.1 7.2 7.9 18.5 13.2 40.9 8.6 20.6 17.1 35.6 13.6 9.8 20.3 12.0 22.4 26.7 22.2 37.7 27.5 28.8 20.4 8.7 29.0 11.6 19.5 0.8 0.2 0.0 0.1 0.1 0.0 0.2 0.1 0.2 0.0 0.1 0.1 0.1 0.2 0.2 0.0 0.2 0.3 0.3 6.2 9.2 5.8 10.5 7.1 7.2 8.8 7.2 8.5 5.5 7.7 14.4 11.1 9.6 7.0 17.0 8.2 8.0 5.2 6.9 13.6 11.7 9.5 8.0 8.7 8.6 9.5 5.5 14.6 10.6 11.0 15.7 1.9 10.5 2.1 10.3 13.7 12.4 7.3 2.5 9.8 8.9 7.9 9.1 26.5 21.1 2.5 14.9 11.4 12.7 13.9 16.8 12.0 16.3 20.3 10.4 5.5 3.1 19.3 9.5 12.4 7.5 8.7 8.8 6.2 9.5 14.3 13.5 10.4 13.5 15.4 9.3 14.6 9.4 12.6 14.2 6.6 10.2 8.8 13.6 13.3 13.2 10.9 9.3 8.9 9.4 12.8 8.2 PTPN7 "HEPTP, LC-PTP" ENSG00000143851 "Protein tyrosine phosphatase non-receptor type 7" P35236 1 202147013-202161588 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.7;lymphoid tissue: 31.1" "Cell type enhanced" "Detected in many" "B-cells: 46.8;dendritic cells: 112.7;granulocytes: 140.7;NK-cells: 99.9;Plasma cells: 63.9;T-cells: 127.2;Theca cells: 54.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 9.8" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "granulocytes: 24.9;NK-cells: 14.9;T-cells: 14.0" "Cell line enhanced" "Detected in some" "HEL: 54.1;HL-60: 118.6;HMC-1: 150.8;NB-4: 51.4;THP-1: 53.7;U-937: 84.0" "Region enriched" "Detected in single" 9 "basal ganglia: 6.1" "Region enriched" "Detected in many" 8 "basal ganglia: 13.3" "CAB009530, HPA019118" Approved Supported "Microtubules,Mitotic spindle,Cytosol" Yes NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Microtubules, Mitotic spindle" "CAB009530: AB_2173845, HPA019118: AB_1855755" "unprognostic (4.19e-3)" "unprognostic (1.08e-3)" "unprognostic (3.09e-2)" "prognostic favorable (1.52e-4)" "unprognostic (2.91e-2)" "prognostic favorable (1.84e-4)" "unprognostic (3.01e-2)" "unprognostic (3.16e-2)" "unprognostic (1.43e-2)" "unprognostic (4.84e-2)" "unprognostic (1.14e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (2.42e-8)" "unprognostic (1.46e-1)" "unprognostic (4.51e-2)" "unprognostic (2.70e-1)" "unprognostic (2.39e-2)" 1.3 4.2 0.6 10.2 9.8 39.7 0.7 1.0 1.8 0.8 0.5 2.2 4.5 1.1 0.0 1.5 0.6 3.2 0.5 0.6 1.2 1.3 1.1 2.5 20.8 2.3 1.5 0.3 0.4 0.1 0.3 0.5 1.8 0.8 2.7 0.0 1.3 0.6 0.1 1.2 5.6 1.5 1.4 9.9 2.4 8.3 2.9 31.1 0.8 0.5 20.8 3.2 0.6 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 12.6 0.0 54.1 0.0 0.0 0.0 118.6 150.8 0.0 0.0 0.0 0.0 0.0 0.1 40.0 2.3 5.0 0.0 0.0 16.3 51.4 0.0 0.0 0.0 2.4 0.0 39.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 53.7 0.3 0.0 0.5 0.0 0.1 22.8 6.3 33.7 0.1 84.0 0.1 17.9 1.5 24.9 13.7 1.5 12.5 2.6 9.2 14.0 2.9 3.2 6.7 8.2 9.9 14.9 0.6 3.8 12.8 4.5 0.6 9.8 1.0 1.8 0.6 1.2 2.3 1.5 1.8 1.4 2.9 2.5 3.2 3.2 5.1 3.3 46.8 2.3 1.3 0.1 0.0 2.7 1.5 1.8 0.7 1.5 0.7 0.0 0.0 0.5 112.7 0.5 0.0 0.5 0.6 0.9 0.8 5.6 0.0 35.5 0.7 0.0 0.2 2.2 1.5 0.7 140.7 6.7 3.6 0.4 15.4 0.0 0.7 0.1 0.0 11.2 31.2 2.4 5.3 21.3 8.8 1.0 10.4 3.8 99.9 1.0 4.6 0.1 0.1 2.2 63.9 0.6 0.2 0.7 0.1 3.7 0.0 0.9 1.1 0.8 0.7 0.5 2.4 0.8 127.2 54.6 0.5 0.6 PWP1 IEF-SSP-9502 ENSG00000136045 "PWP1 homolog, endonuclein" Q13610 12 107685799-107713162 "Predicted intracellular proteins" "Ribosome biogenesis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038708 Approved "Nucleoli rim,Golgi apparatus" Yes No "Cluster 19: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli rim" "Golgi apparatus" "HPA038708: AB_2676163" "unprognostic (7.06e-2)" "unprognostic (1.82e-1)" "unprognostic (2.70e-2)" "unprognostic (1.92e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (9.65e-4)" "prognostic unfavorable (1.40e-5)" "unprognostic (1.97e-2)" "unprognostic (1.41e-1)" "unprognostic (2.66e-1)" "unprognostic (1.08e-1)" "unprognostic (1.89e-1)" "prognostic unfavorable (2.26e-4)" "unprognostic (2.00e-1)" "unprognostic (6.95e-2)" "unprognostic (6.13e-2)" "unprognostic (1.10e-2)" 29.7 20.9 18.6 26.4 19.0 31.9 33.7 18.8 23.6 24.9 29.5 27.7 17.7 30.3 24.8 28.7 24.7 20.4 17.3 18.9 19.1 30.4 32.2 21.4 32.0 17.4 18.0 32.8 25.8 33.0 17.8 29.5 20.0 25.2 26.0 26.9 24.4 27.5 22.9 28.8 21.7 32.3 18.1 23.7 23.1 30.1 18.8 33.2 25.9 17.6 37.4 31.4 24.5 19.0 71.0 86.9 51.8 49.4 70.9 77.2 68.5 72.9 81.9 100.8 84.8 88.5 32.9 108.8 38.4 112.9 68.4 60.7 70.8 77.0 99.2 54.7 80.6 82.9 50.5 103.2 72.7 101.8 56.9 70.2 69.1 93.5 83.0 79.0 119.8 66.0 110.8 29.8 109.1 78.3 71.6 99.3 62.0 64.8 141.2 58.3 61.2 101.4 62.7 98.3 58.4 46.9 59.6 42.4 104.1 64.8 75.3 49.7 94.9 76.7 38.9 63.0 84.1 42.5 62.8 84.9 34.3 55.3 68.7 29.4 20.8 16.2 41.7 27.8 37.8 68.5 40.6 43.9 35.0 64.1 34.5 47.9 6.6 44.2 34.4 47.3 48.6 29.7 18.6 19.0 18.8 23.6 18.9 19.1 17.4 18.0 20.0 18.1 18.8 19.0 44.1 41.7 38.1 13.7 80.1 48.4 52.3 70.6 36.5 50.4 41.0 41.3 22.1 25.8 48.9 27.6 37.5 69.1 48.4 14.6 58.7 69.7 24.4 34.5 47.3 52.0 21.0 52.2 15.6 63.0 74.5 51.6 30.5 35.8 57.6 41.5 43.5 52.0 46.2 33.7 19.0 31.9 26.4 34.3 28.0 11.1 50.4 33.2 30.2 4.7 75.2 41.4 38.1 15.1 16.7 68.0 19.8 44.0 46.0 50.2 24.5 70.8 42.8 46.2 26.3 41.8 50.9 124.3 79.2 41.9 49.7 45.7 44.0 45.8 34.1 40.5 PYCR3 "FLJ13852, PYCRL" ENSG00000104524 "Pyrroline-5-carboxylate reductase 3" Q53H96 8 143603210-143609773 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Proline biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Collecting duct cells: 14.7;Ductal cells: 10.2;Exocrine glandular cells: 9.1;Extravillous trophoblasts: 11.8;Proximal tubular cells: 12.4;Theca cells: 14.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 4.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053776, HPA063416, HPA069706" Uncertain Supported "Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 24: B-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Cytosol "Cytokinetic bridge, Mitotic spindle" "HPA053776: , HPA063416: AB_2685010, HPA069706: AB_2686178" "unprognostic (2.12e-2)" "unprognostic (3.16e-2)" "unprognostic (2.74e-1)" "unprognostic (2.44e-1)" "unprognostic (1.06e-2)" "unprognostic (2.30e-1)" "unprognostic (7.68e-3)" "unprognostic (1.79e-1)" "unprognostic (1.96e-1)" "unprognostic (2.26e-2)" "unprognostic (5.85e-2)" "unprognostic (5.44e-2)" "unprognostic (1.82e-2)" "unprognostic (3.64e-2)" "unprognostic (2.96e-1)" "unprognostic (3.54e-2)" "unprognostic (2.54e-1)" 5.0 9.7 2.8 0.4 2.9 0.6 5.2 2.7 3.3 5.1 1.0 4.2 0.5 5.2 1.1 7.1 6.0 0.8 3.9 2.9 1.6 9.7 17.2 3.8 0.9 2.3 2.2 5.1 9.2 0.6 10.0 0.4 2.7 8.7 0.6 0.7 5.8 0.5 3.0 4.0 4.1 0.4 1.5 5.9 5.5 7.0 2.7 0.4 8.4 0.3 0.7 4.4 3.8 2.1 3.2 4.0 1.6 2.5 1.8 0.6 2.0 3.0 1.4 2.9 1.9 2.9 2.6 6.2 2.1 2.0 1.1 2.6 2.0 4.0 1.1 3.0 5.3 3.7 2.2 2.0 0.6 1.9 1.0 0.8 1.9 3.1 1.9 1.2 0.7 3.7 4.3 3.1 1.9 7.2 3.0 1.7 2.1 4.5 10.4 2.8 1.8 4.3 3.4 2.2 5.3 1.4 3.6 4.9 1.6 0.8 6.4 2.0 0.9 2.9 4.0 3.4 3.1 2.5 0.8 4.2 2.6 2.0 1.9 0.2 0.9 0.0 1.1 0.6 1.2 1.3 0.8 0.8 0.6 4.7 1.1 1.0 0.1 1.3 0.7 3.0 0.9 0.6 2.8 2.9 2.7 3.3 2.9 1.6 2.3 2.2 2.7 1.5 2.7 2.1 2.9 3.2 3.6 0.0 1.8 0.0 0.0 0.0 0.0 0.0 8.8 7.7 0.0 0.0 0.6 14.7 0.0 5.1 1.6 0.0 3.9 10.2 0.0 6.8 6.6 1.9 0.0 0.0 0.0 9.1 11.8 2.9 0.0 5.2 0.0 5.5 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.6 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.8 0.0 0.0 12.4 4.4 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 2.5 1.2 14.7 0.0 0.0 R3HCC1 DKFZp564N123 ENSG00000104679 "R3H domain and coiled-coil containing 1" Q9Y3T6 8 23270120-23296279 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 113.2;Rod photoreceptor cells: 115.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023073, HPA023153" Uncertain Approved Nucleoplasm,Cytosol "Intracellular and membrane" Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 54: Non-specific - Microtubule organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol Nucleoplasm "HPA023073: AB_1855987, HPA023153: AB_2237834" "unprognostic (5.80e-2)" "unprognostic (4.70e-3)" "prognostic favorable (4.08e-4)" "unprognostic (7.46e-3)" "unprognostic (1.97e-1)" "unprognostic (7.26e-2)" "unprognostic (8.49e-3)" "unprognostic (1.02e-2)" "unprognostic (7.73e-2)" "unprognostic (2.92e-1)" "prognostic favorable (8.66e-4)" "unprognostic (7.65e-2)" "prognostic favorable (6.80e-5)" "unprognostic (1.22e-2)" "unprognostic (1.17e-1)" "unprognostic (4.18e-1)" "unprognostic (3.43e-1)" 20.5 21.9 41.2 15.2 52.7 29.0 19.6 53.7 43.8 23.4 36.4 33.6 19.7 23.9 14.8 16.1 22.5 16.2 33.1 39.9 42.3 20.1 28.2 16.7 22.5 60.9 49.8 27.2 42.8 29.0 22.6 13.7 63.6 22.7 15.3 62.7 35.7 19.9 54.5 22.5 20.4 22.2 49.3 20.2 28.4 30.8 48.6 20.3 17.6 31.5 18.8 22.2 17.8 73.7 38.2 48.7 36.7 35.9 15.2 20.6 25.2 24.7 23.4 41.0 29.7 35.0 17.6 38.1 25.6 30.2 28.0 28.3 38.9 45.8 27.5 24.7 41.6 35.7 33.4 29.2 36.0 24.7 25.6 24.8 35.5 35.0 16.4 30.1 31.7 42.9 41.8 31.0 24.3 33.1 55.6 43.8 29.8 40.4 35.8 37.9 44.8 22.8 20.3 41.9 47.2 41.1 28.1 32.8 41.8 25.0 30.3 29.2 27.4 37.9 31.8 32.2 51.1 23.8 22.2 39.3 29.5 34.3 48.5 38.4 50.5 82.5 64.8 44.1 56.5 56.5 52.7 55.0 56.7 42.1 40.5 47.0 31.3 59.5 50.3 52.9 61.5 51.4 41.2 52.7 53.7 43.8 39.9 42.3 60.9 49.8 63.6 49.3 48.6 73.7 25.2 25.6 14.7 4.9 15.5 14.9 16.5 35.9 10.2 28.0 22.8 32.9 24.1 24.3 20.5 5.5 27.1 18.8 19.8 17.9 56.7 32.3 36.4 15.2 17.0 21.1 19.2 17.9 5.1 50.9 21.3 25.4 20.9 10.2 22.8 24.7 20.0 21.6 30.2 18.5 5.0 21.5 22.4 18.2 12.3 113.2 17.7 16.2 21.4 5.6 18.8 59.3 42.2 4.5 9.5 37.0 22.1 21.8 34.7 11.4 41.7 38.5 22.0 115.7 13.1 19.9 31.1 49.8 32.4 13.6 16.2 7.7 18.3 30.7 22.8 13.6 RAB11FIP3 "eferin, KIAA0665, Rab11-FIP3" ENSG00000090565 "RAB11 family interacting protein 3" O75154 16 425649-523011 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 151.1" "Cell type enriched" "Detected in many" 5 "Proximal tubular cells: 384.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028088, HPA028631, HPA030086" Enhanced Enhanced "Nucleoplasm,Vesicles,Cytokinetic bridge,Centriolar satellite,Mitochondria" Yes No "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Centriolar satellite" "Nucleoplasm, Cytokinetic bridge, Mitochondria" "HPA028088: AB_10601672, HPA028631: AB_10601853, HPA030086: AB_10669596" "unprognostic (6.65e-2)" "unprognostic (1.84e-2)" "unprognostic (1.51e-1)" "prognostic favorable (1.22e-4)" "unprognostic (2.87e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (9.87e-5)" "unprognostic (6.71e-2)" "unprognostic (4.74e-1)" "unprognostic (9.66e-2)" "prognostic favorable (3.16e-5)" "unprognostic (1.12e-1)" "prognostic favorable (7.99e-4)" "unprognostic (1.39e-1)" "unprognostic (1.77e-1)" "unprognostic (1.58e-1)" "unprognostic (1.44e-1)" 27.9 32.3 18.0 5.3 18.9 7.0 19.5 21.3 22.6 29.6 7.6 35.1 9.0 31.3 5.5 12.3 27.5 7.4 31.4 21.7 14.0 151.1 37.3 25.2 5.8 14.4 15.8 33.8 47.4 15.9 41.5 6.5 15.2 29.9 3.1 6.1 19.3 7.8 52.2 19.5 27.5 7.1 12.7 26.4 22.2 34.6 16.8 5.3 24.8 15.8 3.2 31.7 19.9 19.0 5.9 14.9 14.6 11.9 20.2 13.2 10.0 10.6 11.6 10.7 7.6 11.5 3.0 15.3 11.0 18.7 8.9 5.5 8.9 13.4 3.9 10.8 14.9 7.9 14.8 31.7 20.9 9.5 8.6 12.7 8.8 11.6 9.9 11.7 17.3 10.7 3.5 6.0 14.4 22.5 10.2 15.9 11.7 5.0 6.8 22.8 10.8 4.6 11.3 4.0 13.8 12.0 11.5 13.6 7.5 5.0 7.6 13.9 29.9 14.8 8.8 13.6 7.0 6.9 6.7 18.8 6.5 5.8 11.7 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 18.0 18.9 21.3 22.6 21.7 14.0 14.4 15.8 15.2 12.7 16.8 19.0 9.4 3.2 1.7 36.9 3.8 3.7 0.7 1.1 2.2 7.7 3.5 4.3 12.4 7.2 4.3 5.5 6.2 1.0 5.7 5.9 27.4 1.6 1.2 6.4 8.7 7.1 3.0 1.7 73.5 1.2 0.2 5.5 2.0 13.1 1.3 8.4 17.9 15.9 0.8 21.9 60.3 3.0 0.0 3.7 1.6 2.6 0.6 4.7 0.0 19.7 0.6 7.2 2.1 46.8 40.7 1.4 3.9 1.9 3.4 0.9 8.1 384.2 3.1 7.6 6.6 5.3 5.4 4.0 2.8 0.3 2.3 0.8 4.4 6.1 5.9 0.3 RACGAP1 MgcRacGAP ENSG00000161800 "Rac GTPase activating protein 1" Q9H0H5 12 49976923-50033136 "Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Ion transport, Spermatogenesis, Transport" "Developmental protein, GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 38.9;lymphoid tissue: 43.0;testis: 45.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 55.7;Extravillous trophoblasts: 49.4;Spermatocytes: 79.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025859, HPA039427, HPA043912" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB025859: , HPA039427: AB_2676503, HPA043912: AB_2678728" "prognostic unfavorable (1.51e-4)" "unprognostic (1.91e-1)" "unprognostic (3.74e-3)" "unprognostic (1.53e-2)" "unprognostic (1.58e-1)" "unprognostic (4.82e-2)" "prognostic unfavorable (1.86e-6)" "unprognostic (1.15e-3)" "unprognostic (3.07e-3)" "unprognostic (5.31e-2)" "prognostic unfavorable (4.12e-6)" "unprognostic (5.56e-2)" "prognostic unfavorable (3.98e-8)" "unprognostic (3.13e-2)" "unprognostic (4.94e-1)" "unprognostic (6.16e-2)" "unprognostic (2.15e-1)" 5.0 2.5 5.5 13.7 8.2 38.9 7.1 6.9 6.3 5.2 3.2 16.7 10.5 5.3 1.5 21.3 4.4 6.4 2.8 5.0 6.0 9.2 4.7 6.2 23.9 6.7 7.1 2.4 2.7 5.8 1.4 14.0 6.5 3.3 18.7 5.3 4.8 3.4 4.9 14.4 11.6 12.5 5.5 6.5 9.8 45.5 7.6 43.0 3.3 4.8 30.2 7.7 8.0 7.0 193.0 174.5 135.8 86.8 24.8 29.7 113.0 195.0 97.0 207.3 140.3 174.6 144.7 107.5 86.0 108.3 99.9 127.1 137.7 93.6 219.9 203.0 85.4 137.9 165.8 58.1 8.4 146.1 109.0 16.2 17.2 140.7 111.4 60.3 71.7 96.4 101.6 159.6 197.0 136.8 122.5 72.6 96.2 108.9 112.9 113.9 163.5 78.3 54.9 95.7 113.9 97.5 161.7 102.7 53.0 68.8 199.7 64.8 64.9 136.2 119.1 86.8 144.7 83.3 225.2 126.6 67.7 97.0 81.1 24.1 3.2 4.7 6.5 4.1 5.7 8.2 7.9 9.2 2.8 4.3 4.6 6.1 0.7 11.0 2.6 1.8 19.1 5.8 5.5 8.2 6.9 6.3 5.0 6.0 6.7 7.1 6.5 5.5 7.6 7.0 2.0 6.4 6.4 2.9 4.2 12.9 2.5 4.9 6.2 1.5 4.8 5.1 1.5 2.8 3.3 5.5 4.2 21.8 4.4 3.1 19.6 1.9 15.2 2.2 3.1 2.7 0.0 55.7 7.5 2.2 49.4 5.9 7.7 4.0 2.5 14.2 5.3 2.7 13.1 1.7 8.0 5.7 20.3 11.3 8.0 17.7 1.5 7.1 1.8 1.0 4.5 2.7 6.2 6.0 12.3 2.0 1.0 3.8 10.9 2.8 1.1 2.1 2.3 0.8 13.1 3.1 5.5 79.6 32.2 19.5 12.9 8.6 6.9 2.2 11.6 2.9 RAD51AP1 PIR51 ENSG00000111247 "RAD51 associated protein 1" Q96B01 12 4538798-4560047 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Meiosis" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.9;lymphoid tissue: 14.4" "Cell type enhanced" "Detected in many" "Early spermatids: 33.4;Erythroid cells: 47.8;Extravillous trophoblasts: 34.1;Hofbauer cells: 40.8;Late spermatids: 68.1;Spermatocytes: 35.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051499 Approved Nucleoplasm Yes Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA051499: AB_2681508" "unprognostic (1.03e-1)" "unprognostic (5.44e-3)" "unprognostic (1.84e-1)" "prognostic unfavorable (9.42e-4)" "unprognostic (6.30e-2)" "unprognostic (5.25e-3)" "prognostic unfavorable (3.53e-4)" "unprognostic (2.15e-2)" "unprognostic (2.26e-2)" "unprognostic (6.29e-3)" "prognostic unfavorable (1.22e-5)" "unprognostic (1.00e-1)" "prognostic unfavorable (4.44e-15)" "unprognostic (2.68e-2)" "unprognostic (2.22e-1)" "unprognostic (6.88e-2)" "unprognostic (3.75e-2)" 0.9 0.8 0.3 4.8 0.4 16.9 2.7 0.4 0.7 0.9 0.3 5.2 5.2 1.2 0.6 3.2 1.0 1.1 0.5 0.3 0.3 0.8 1.8 1.4 8.9 0.4 0.4 0.5 0.4 0.6 0.3 3.8 0.4 1.3 6.5 1.5 1.0 1.0 0.5 3.2 4.8 1.9 0.4 3.4 2.7 6.3 0.4 14.4 1.0 0.6 7.9 1.7 1.3 0.5 37.5 13.0 45.3 22.7 2.7 5.7 53.0 48.2 21.2 52.6 68.9 35.4 35.4 48.6 7.0 10.4 24.7 23.1 31.8 14.5 80.0 38.7 27.0 61.4 21.6 24.8 0.6 56.6 29.9 1.2 1.5 31.6 30.4 7.5 21.4 33.0 39.2 54.4 33.7 13.6 46.5 20.5 110.4 36.3 14.4 46.0 54.3 19.2 16.1 18.3 15.1 16.6 35.9 27.7 11.6 45.5 11.3 32.6 9.5 35.5 36.5 38.8 52.4 7.8 10.0 93.3 13.3 40.0 29.4 0.0 0.5 0.7 0.1 2.3 0.5 3.1 0.4 1.0 0.4 3.4 0.1 0.2 0.0 1.4 2.0 6.9 1.0 0.6 0.3 0.4 0.4 0.7 0.3 0.3 0.4 0.4 0.4 0.4 0.4 0.5 1.4 0.0 0.5 0.7 6.1 5.2 2.3 6.6 1.2 3.1 3.4 5.7 1.4 2.8 4.5 0.0 4.2 20.3 11.3 5.7 0.0 3.0 33.4 3.3 2.9 2.9 2.4 47.8 2.7 2.7 34.1 5.2 6.1 3.6 1.3 22.6 2.5 1.2 40.8 0.0 1.1 6.4 16.2 6.2 5.6 68.1 1.2 10.1 0.0 3.7 6.8 2.7 3.1 0.5 2.4 1.5 0.8 1.5 15.5 1.0 1.2 1.5 0.9 4.8 0.0 2.4 4.2 35.9 25.0 10.0 2.6 4.7 4.6 2.0 14.6 2.7 RANBP17 ENSG00000204764 "RAN binding protein 17" Q9H2T7 5 170861870-171300015 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.3" "Cell type enhanced" "Detected in many" "Early spermatids: 112.7;Excitatory neurons: 100.6;Glandular and luminal cells: 59.5;Inhibitory neurons: 152.9;Oligodendrocyte precursor cells: 65.4;Oligodendrocytes: 87.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 4.0;SK-BR-3: 3.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029568, HPA029569" Uncertain Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies,Cytosol" Yes No "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nuclear bodies" "Nuclear membrane, Cytosol" "HPA029568: AB_10599825, HPA029569: AB_10601571" "unprognostic (4.63e-2)" "unprognostic (2.63e-3)" "unprognostic (1.06e-1)" "unprognostic (8.28e-2)" "unprognostic (1.75e-3)" "unprognostic (5.12e-3)" "unprognostic (1.50e-1)" "unprognostic (2.45e-1)" "unprognostic (1.31e-1)" "unprognostic (2.00e-1)" "unprognostic (1.54e-1)" "unprognostic (9.59e-2)" "unprognostic (1.64e-2)" "unprognostic (2.19e-3)" "unprognostic (2.72e-1)" "unprognostic (1.35e-1)" "unprognostic (2.56e-3)" 0.2 0.8 0.3 0.1 0.2 0.1 0.2 2.3 0.6 0.2 0.8 0.2 0.2 0.5 0.2 0.0 0.4 0.5 0.2 0.1 1.1 0.4 0.3 0.8 0.3 0.9 0.9 0.2 1.4 0.8 0.4 0.8 1.3 0.4 0.4 0.8 0.8 0.5 0.0 0.1 0.3 0.3 0.6 0.0 0.3 1.4 0.6 0.2 1.0 0.0 0.1 0.1 0.1 1.1 0.0 0.7 4.0 3.3 1.3 0.3 2.4 2.6 1.2 1.8 1.1 1.5 0.0 0.1 2.0 2.5 0.0 0.0 0.0 1.2 3.5 0.0 2.4 0.7 1.4 0.0 1.1 0.0 0.0 2.6 0.2 0.2 0.0 0.2 1.7 0.0 0.3 0.0 1.0 1.7 0.0 0.0 0.3 0.6 0.2 0.0 2.4 0.0 0.6 1.0 0.2 1.4 0.0 3.9 1.5 1.7 0.7 1.2 2.4 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 2.3 0.6 0.1 1.1 0.9 0.9 1.3 0.6 0.6 1.1 9.4 9.6 2.0 12.7 0.0 0.3 6.2 5.8 1.8 24.8 6.1 2.8 1.3 7.2 4.8 0.0 14.6 10.4 1.7 2.3 0.0 7.3 112.7 22.4 17.5 7.9 5.4 5.5 100.6 1.4 3.2 4.9 5.1 59.5 0.0 15.6 4.2 1.6 1.9 0.0 152.9 3.7 2.0 0.6 1.4 46.5 2.8 1.0 1.8 9.4 1.2 5.5 5.2 65.4 87.1 5.3 2.9 3.0 0.8 13.0 3.9 0.9 2.4 26.9 0.0 3.0 5.1 27.2 26.7 1.4 0.0 2.5 0.8 7.5 6.3 7.6 RANGAP1 "Fug1, KIAA1835, SD" ENSG00000100401 "Ran GTPase activating protein 1" P46060 22 41244779-41286187 "Plasma proteins, Predicted intracellular proteins, Transporters" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Late spermatids: 1717.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004293, HPA050110, HPA062034" Supported Enhanced "Nuclear membrane,Vesicles,Cytosol" Yes Yes 75000 "Cluster 27: Non-specific - Gene expression" "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear membrane" "Vesicles, Cytosol" "CAB004293: AB_2176987, HPA050110: AB_2681018, HPA062034: AB_2684667" "unprognostic (1.30e-2)" "unprognostic (3.16e-2)" "unprognostic (1.66e-1)" "unprognostic (7.97e-2)" "unprognostic (2.57e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (8.28e-3)" "unprognostic (8.09e-2)" "unprognostic (9.87e-2)" "unprognostic (5.84e-2)" "unprognostic (7.56e-2)" "unprognostic (7.07e-3)" "prognostic favorable (5.39e-4)" "unprognostic (2.06e-1)" "unprognostic (2.74e-1)" "unprognostic (2.68e-1)" 27.5 72.9 78.2 26.0 86.0 48.1 29.6 70.8 102.3 34.4 47.7 29.2 18.1 24.9 12.0 79.8 23.6 17.2 45.1 79.5 85.2 43.9 88.0 41.6 30.6 102.7 77.9 32.5 60.9 12.7 57.4 22.8 105.1 39.3 13.2 32.7 38.0 17.6 43.0 96.9 30.6 17.5 68.7 42.3 39.6 178.1 82.0 40.4 34.4 14.2 31.8 34.7 45.4 109.1 228.0 112.2 75.9 77.3 38.8 31.4 85.9 194.5 103.8 182.8 98.4 135.9 71.9 118.0 154.0 137.4 94.8 203.0 135.5 145.4 125.2 95.7 199.2 103.3 115.0 107.9 46.7 171.6 72.5 30.0 69.5 132.2 123.4 67.6 102.1 45.0 127.7 83.3 111.9 186.1 96.3 130.0 84.5 217.6 127.6 118.8 73.4 126.0 72.5 123.7 66.6 44.1 139.1 117.7 71.7 74.6 72.2 64.4 146.5 141.7 138.5 78.6 154.6 60.1 92.8 124.2 99.3 119.3 82.0 2.7 7.6 6.9 8.1 9.0 9.5 5.9 8.2 7.8 5.6 6.4 7.4 5.9 2.0 5.9 12.9 5.9 9.5 8.2 78.2 86.0 70.8 102.3 79.5 85.2 102.7 77.9 105.1 68.7 82.0 109.1 10.9 3.2 20.9 8.5 15.0 23.1 22.2 10.9 18.2 16.0 22.4 16.9 19.6 25.8 9.6 9.2 14.6 22.7 20.3 22.9 3.9 33.3 270.7 21.0 14.7 16.1 25.0 16.6 28.3 20.3 35.3 13.3 25.5 25.1 6.3 74.4 8.9 21.8 16.6 15.2 20.8 19.1 16.2 13.9 20.9 1717.0 14.9 16.8 12.4 5.6 8.9 10.1 14.4 6.0 32.2 39.8 5.7 12.0 25.8 37.4 7.1 13.1 11.4 26.4 0.0 6.8 18.2 25.6 17.7 38.8 31.0 23.7 24.3 42.5 24.8 23.3 RANGRF "HSPC165, HSPC236, MOG1, RANGNRF" ENSG00000108961 "RAN guanine nucleotide release factor" Q9HD47 17 8288654-8290092 "Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 435.1;Late spermatids: 1448.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057280, HPA057888" Approved Supported Nucleoplasm,Cytosol Yes No "Cluster 35: T-regs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA057280: AB_2683393, HPA057888: AB_2683549" "unprognostic (2.87e-2)" "unprognostic (2.93e-2)" "unprognostic (7.41e-2)" "prognostic favorable (1.65e-4)" "unprognostic (1.47e-2)" "unprognostic (2.51e-1)" "unprognostic (1.90e-3)" "unprognostic (2.26e-2)" "unprognostic (2.45e-1)" "unprognostic (2.01e-2)" "prognostic favorable (4.39e-4)" "unprognostic (1.43e-1)" "unprognostic (6.34e-2)" "unprognostic (3.11e-1)" "unprognostic (1.01e-1)" "unprognostic (2.14e-1)" "unprognostic (1.13e-2)" 28.3 27.6 40.9 18.8 42.4 20.5 29.2 39.9 43.8 47.4 40.6 38.1 15.8 36.9 31.9 15.7 35.1 16.9 41.6 40.6 42.5 44.2 18.6 25.3 33.0 40.6 41.3 36.3 15.1 43.8 32.7 22.7 41.1 35.5 15.9 34.8 13.1 27.6 24.1 19.4 28.1 27.1 41.4 33.3 39.0 78.4 43.1 34.0 25.1 26.0 32.3 34.7 23.3 41.0 52.8 59.5 41.0 42.7 30.0 41.0 35.4 29.7 59.9 75.3 72.7 30.4 20.3 98.4 31.7 35.9 29.7 58.0 77.7 39.3 53.7 71.2 97.6 46.6 45.0 46.6 72.9 30.7 66.2 39.6 75.1 66.4 66.4 38.9 65.5 93.4 21.2 27.1 48.9 1.3 91.7 98.4 29.7 29.8 22.7 81.1 32.0 61.8 44.4 21.3 15.7 45.2 23.5 36.2 65.0 25.9 2.8 28.3 36.3 16.4 29.5 33.0 58.4 47.5 40.0 121.4 35.1 60.8 24.1 17.2 47.6 81.5 68.2 50.7 64.4 74.7 82.8 78.1 51.5 82.0 72.3 61.6 5.9 70.1 41.0 67.8 129.9 57.5 40.9 42.4 39.9 43.8 40.6 42.5 40.6 41.3 41.1 41.4 43.1 41.0 21.2 9.6 26.1 6.2 35.8 18.1 24.3 23.5 25.0 26.2 31.4 36.2 4.7 12.8 17.5 25.8 12.5 93.2 25.4 9.4 68.4 25.5 435.1 19.0 18.8 26.0 19.8 15.4 6.2 18.3 46.4 25.3 14.8 19.3 27.8 19.0 23.9 17.3 49.3 20.2 9.0 17.4 26.4 16.4 19.2 1448.8 28.3 18.9 17.8 1.9 29.5 33.6 58.7 3.0 9.5 21.1 21.2 31.6 37.5 22.9 14.3 66.7 14.3 38.4 19.7 16.3 34.0 180.6 23.0 10.6 19.6 112.9 35.6 28.1 21.8 16.1 RAPGEFL1 Link-GEFII ENSG00000108352 "Rap guanine nucleotide exchange factor like 1" Q9UHV5 17 40177010-40195656 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 199.1;skin 1: 237.7;vagina: 113.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 87.7;Excitatory neurons: 47.8;Proximal enterocytes: 55.3;Squamous epithelial cells: 95.4;Suprabasal keratinocytes: 97.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HaCaT: 92.4;hTCEpi: 45.8;T-47d: 80.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022895 Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes No "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Microtubules" "Cytokinetic bridge" "HPA022895: AB_1856071" "prognostic favorable (8.43e-4)" "prognostic favorable (3.28e-4)" "unprognostic (1.61e-1)" "unprognostic (1.13e-2)" "unprognostic (4.64e-3)" "unprognostic (3.48e-2)" "unprognostic (5.92e-2)" "unprognostic (1.80e-1)" "unprognostic (3.64e-2)" "unprognostic (2.67e-1)" "unprognostic (7.46e-3)" "unprognostic (8.84e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.23e-2)" "unprognostic (1.50e-1)" "unprognostic (1.15e-1)" "unprognostic (2.03e-2)" 6.3 4.4 38.4 6.8 36.1 4.4 9.1 12.1 58.3 48.7 1.8 53.8 48.3 4.6 9.9 199.1 6.6 8.8 6.8 55.1 12.9 3.8 10.5 8.0 2.2 12.0 11.4 3.7 7.9 1.1 14.2 2.3 10.9 17.7 44.5 6.1 27.4 6.9 12.6 237.7 40.6 4.0 8.3 7.3 31.8 10.2 15.2 3.3 4.5 2.8 20.7 21.9 113.2 30.6 5.3 2.6 13.7 10.2 1.5 3.3 6.6 1.9 1.4 2.7 3.2 6.0 7.6 4.2 1.9 2.7 2.4 92.4 2.7 3.3 3.8 7.7 6.9 2.5 3.6 6.0 1.7 5.2 8.5 3.9 45.8 2.8 1.3 4.0 4.1 13.9 1.9 2.8 2.1 14.6 4.9 6.3 4.3 26.1 2.6 8.8 1.6 2.6 1.7 27.6 26.2 5.3 3.3 31.2 1.3 11.5 80.7 3.9 7.9 3.3 6.8 3.5 3.2 4.6 4.7 3.4 7.8 3.2 4.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 38.4 36.1 12.1 58.3 55.1 12.9 12.0 11.4 10.9 8.3 15.2 30.6 1.9 0.0 1.1 7.5 1.0 45.5 9.7 14.0 13.1 5.7 2.6 3.7 2.4 11.5 10.9 1.8 6.2 0.2 0.7 87.7 0.0 0.9 2.7 5.9 2.1 2.2 4.9 2.7 47.8 0.8 0.3 1.4 32.6 9.4 5.7 1.7 3.9 4.4 0.5 1.7 32.1 31.9 6.1 1.2 5.2 2.2 3.4 1.9 5.4 1.0 2.4 2.9 1.0 8.0 5.0 1.6 44.6 3.8 0.1 10.9 55.3 0.1 6.5 4.4 0.0 2.1 1.9 12.0 15.0 95.4 97.0 0.7 1.1 1.8 44.1 39.2 RASL11A ENSG00000122035 "RAS like family 11 member A" Q6T310 13 27270830-27275192 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 29.6;Fibroblasts: 30.1;Gastric mucus-secreting cells: 42.3;Sertoli cells: 32.9;Smooth muscle cells: 112.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 1.3" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 4 "ASC diff: 42.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA004859, HPA053296" Supported Approved "Nuclear bodies" Yes No "Cluster 51: Monocytes - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear bodies" "HPA004859: AB_2667270, HPA053296: AB_2682106" "unprognostic (1.59e-1)" "unprognostic (9.11e-2)" "unprognostic (2.30e-1)" "unprognostic (1.17e-1)" "unprognostic (2.71e-1)" "unprognostic (2.09e-2)" "unprognostic (6.65e-2)" "prognostic favorable (5.43e-4)" "unprognostic (3.85e-1)" "unprognostic (7.98e-2)" "unprognostic (2.65e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (3.52e-4)" "unprognostic (1.49e-1)" "unprognostic (2.54e-1)" "unprognostic (3.71e-2)" "unprognostic (3.34e-1)" 32.9 4.1 1.9 3.1 3.2 2.3 21.8 3.1 3.1 21.4 2.1 20.4 7.7 21.6 3.9 9.8 22.0 3.8 11.3 3.2 1.7 30.4 12.9 13.0 10.8 1.8 2.2 9.5 4.9 1.4 10.6 2.9 2.0 20.3 12.5 0.1 5.3 5.6 3.5 10.1 20.9 5.5 2.2 14.8 13.4 2.9 3.3 1.2 12.1 1.7 10.0 19.1 15.9 2.4 0.3 1.3 0.3 0.6 42.4 4.3 0.2 1.9 1.8 0.1 0.1 8.1 0.8 0.3 0.5 1.4 0.9 0.1 2.5 0.8 0.1 1.7 8.8 1.8 0.2 0.5 6.8 0.6 0.6 5.0 0.7 0.1 0.1 1.7 0.6 0.7 0.3 0.1 0.0 0.8 0.0 2.4 1.5 8.0 10.2 0.5 0.0 0.2 1.4 6.2 0.7 0.3 0.7 3.3 0.2 1.0 0.2 0.8 0.3 0.1 0.3 2.9 0.4 0.1 0.0 0.0 0.4 1.9 0.1 0.4 0.4 0.4 0.0 0.5 0.1 0.1 0.0 0.0 0.2 1.2 0.1 0.1 0.2 0.1 1.3 0.1 0.0 0.1 1.9 3.2 3.1 3.1 3.2 1.7 1.8 2.2 2.0 2.2 3.3 2.4 29.6 16.0 11.2 0.3 6.0 4.6 3.2 0.9 17.6 0.0 6.2 11.9 1.4 0.0 8.6 7.3 0.0 0.7 4.5 9.3 3.9 1.8 0.0 5.1 9.8 5.9 0.0 4.0 0.6 2.4 0.2 30.1 42.3 6.1 0.0 2.1 2.5 0.2 1.4 0.0 0.6 5.6 4.1 0.8 6.5 0.0 0.3 6.1 1.8 1.9 1.7 0.3 0.0 0.5 1.8 0.5 12.7 1.5 17.1 1.1 11.4 1.7 10.3 0.2 32.9 11.6 112.0 0.0 0.0 13.5 4.4 0.8 4.5 1.2 6.7 1.1 RASSF4 "AD037, MGC44914" ENSG00000107551 "Ras association domain family member 4" Q9H2L5 10 44959407-44995891 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 77.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 157.0;monocytes: 258.7;Muller glia cells: 260.3;Proximal tubular cells: 128.0;Skeletal myocytes: 186.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 84.8;intermediate monocyte: 63.9;myeloid DC: 84.2;non-classical monocyte: 37.9" "Group enriched" "Detected in many" 10 "dendritic cells: 84.2;monocytes: 84.8" "Cell line enhanced" "Detected in many" "Karpas-707: 64.3;RH-30: 162.7;RPMI-8226: 54.9;U-937: 85.4;WM-115: 54.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038834, HPA077069" Approved Approved "Nucleoplasm,Nucleoli,Cell Junctions,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 5: Muller glia cells - Visual perception" "Nucleoplasm, Nucleoli" "Cell Junctions, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA038834: AB_10795576, HPA077069: " "unprognostic (1.83e-1)" "unprognostic (8.21e-3)" "unprognostic (1.21e-2)" "unprognostic (1.04e-1)" "unprognostic (1.25e-1)" "unprognostic (5.14e-2)" "unprognostic (3.15e-2)" "unprognostic (2.18e-2)" "unprognostic (8.81e-2)" "unprognostic (4.83e-2)" "unprognostic (8.75e-3)" "unprognostic (4.20e-1)" "unprognostic (4.11e-3)" "unprognostic (4.02e-2)" "unprognostic (2.22e-2)" "unprognostic (1.42e-1)" "unprognostic (6.20e-2)" 35.3 7.1 57.4 21.7 67.9 8.3 22.7 64.3 58.6 6.5 43.8 18.5 13.6 3.0 8.6 4.7 6.0 10.8 44.8 53.9 58.9 77.3 17.1 11.9 19.7 63.4 64.0 3.6 39.5 5.0 13.0 12.7 65.9 7.9 6.0 26.9 16.7 10.9 14.8 4.8 13.8 8.7 55.8 20.1 9.4 9.0 65.3 10.4 40.7 17.6 9.1 11.4 7.0 69.7 1.4 0.3 6.0 11.4 17.9 1.0 4.1 0.7 1.1 2.0 3.5 5.0 0.6 0.1 2.3 0.8 3.9 0.0 2.6 2.8 2.8 37.8 0.0 0.1 0.2 39.7 19.0 2.6 0.0 13.1 0.0 1.9 0.2 10.9 3.0 1.6 0.0 64.3 2.9 0.0 3.0 43.1 1.2 0.2 1.2 8.1 162.7 54.9 0.4 1.2 1.0 0.8 0.0 0.5 2.0 10.7 1.1 32.4 0.0 0.4 3.6 3.0 6.5 0.7 0.7 0.1 18.9 85.4 54.8 0.0 84.8 0.1 8.7 63.9 0.2 0.0 0.6 3.7 84.2 0.0 0.6 2.6 3.0 6.9 37.9 2.2 0.3 48.9 57.4 67.9 64.3 58.6 53.9 58.9 63.4 64.0 65.9 55.8 65.3 69.7 8.9 19.2 17.2 77.4 3.7 3.7 1.4 3.2 1.2 22.5 9.7 7.0 47.9 37.1 13.1 16.5 4.2 1.2 20.3 10.1 17.6 45.3 1.4 6.4 13.7 9.2 11.5 0.0 17.0 3.8 1.2 28.6 1.5 14.8 1.3 4.2 6.1 20.1 157.0 37.0 33.6 7.4 12.2 84.7 94.3 4.4 10.5 91.0 8.8 35.6 258.7 260.3 54.6 37.7 38.2 4.0 11.3 2.2 4.1 1.0 45.0 128.0 5.9 13.3 26.3 186.4 25.9 0.6 1.9 0.8 1.7 2.6 8.0 4.9 15.0 0.7 RBL2 "p130, Rb2" ENSG00000103479 "RB transcriptional corepressor like 2" Q08999 16 53433977-53491648 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 468.3;Late spermatids: 209.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016547, HPA019703" Supported Supported "Nucleoplasm,Nucleoli rim,Mitotic chromosome,Cytosol" Yes No "Cluster 48: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 58: T-cells - T-cell receptor" "Nucleoplasm, Nucleoli rim, Mitotic chromosome" Cytosol "CAB016547: AB_785011, HPA019703: AB_1856106" "unprognostic (1.51e-1)" "unprognostic (4.38e-2)" "unprognostic (4.00e-2)" "unprognostic (1.26e-1)" "unprognostic (6.88e-2)" "unprognostic (6.43e-2)" "unprognostic (5.03e-2)" "unprognostic (2.46e-2)" "unprognostic (1.04e-1)" "unprognostic (2.11e-1)" "unprognostic (4.70e-1)" "unprognostic (8.12e-2)" "prognostic favorable (3.57e-5)" "unprognostic (9.57e-3)" "unprognostic (1.02e-1)" "unprognostic (8.70e-2)" "unprognostic (7.51e-2)" 32.5 25.4 11.1 32.3 13.6 19.1 31.7 12.5 10.4 33.5 14.8 26.6 23.3 32.2 20.2 25.0 31.8 27.7 25.6 8.7 10.5 39.2 59.5 38.9 49.7 12.3 12.0 37.8 39.0 62.7 17.7 19.3 13.0 42.9 29.3 23.1 34.2 39.9 32.4 26.3 26.1 30.7 11.7 41.0 32.6 48.4 11.4 66.6 40.2 37.7 51.2 30.9 28.9 16.9 25.9 18.1 20.7 20.6 61.2 57.9 9.4 17.8 26.4 23.1 7.9 10.1 30.9 39.0 28.4 32.8 22.3 29.6 17.9 30.1 36.0 12.5 22.4 15.9 14.7 22.0 27.3 23.4 49.0 35.6 34.0 15.3 22.4 43.0 36.3 39.6 12.7 23.2 26.6 7.1 48.6 22.0 7.8 30.8 15.0 33.6 41.8 46.1 25.4 25.3 16.9 14.3 42.2 17.2 19.1 16.8 22.7 30.0 28.3 27.5 14.3 24.1 13.7 35.7 22.9 42.4 34.4 28.2 19.0 53.9 22.5 56.5 53.4 16.2 60.5 22.5 59.7 62.8 21.7 22.0 85.5 75.3 41.8 74.4 28.8 13.1 48.2 76.2 11.1 13.6 12.5 10.4 8.7 10.5 12.3 12.0 13.0 11.7 11.4 16.9 37.9 41.7 101.1 51.2 49.5 23.1 30.1 15.3 40.9 27.8 27.0 15.5 13.5 45.8 32.5 27.6 20.9 6.0 77.0 26.3 17.6 13.4 468.3 38.9 25.8 31.4 19.8 26.5 55.1 10.2 13.0 35.8 24.5 45.9 55.1 27.9 40.7 46.1 11.2 35.3 54.1 30.0 34.6 43.6 23.7 209.1 42.0 35.4 10.6 58.1 44.9 38.3 79.3 63.3 85.7 10.8 19.0 42.9 48.7 31.4 29.2 25.3 38.3 22.5 39.5 36.2 26.1 161.4 61.3 33.7 27.6 4.1 118.9 25.2 21.7 35.6 RBM18 MGC2734 ENSG00000119446 "RNA binding motif protein 18" Q96H35 9 122237622-122264840 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057281, HPA077955" Uncertain Enhanced "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA057281: AB_2683394, HPA077955: " "unprognostic (1.75e-2)" "unprognostic (7.23e-2)" "unprognostic (2.70e-1)" "unprognostic (1.44e-1)" "unprognostic (5.81e-3)" "unprognostic (2.52e-3)" "unprognostic (1.08e-1)" "unprognostic (9.39e-3)" "unprognostic (7.27e-3)" "unprognostic (2.79e-2)" "unprognostic (1.45e-1)" "unprognostic (8.51e-2)" "prognostic favorable (8.00e-7)" "unprognostic (2.88e-1)" "unprognostic (1.60e-1)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" 9.0 9.5 7.4 6.4 7.9 11.7 16.4 8.0 10.1 8.9 7.3 7.5 7.0 8.8 10.3 7.7 7.4 7.6 13.5 7.8 8.8 11.4 8.4 7.2 8.1 8.2 7.9 9.5 6.9 11.9 5.7 10.4 8.6 11.1 8.1 11.5 7.9 8.3 20.7 6.8 6.1 8.7 8.0 8.0 8.5 3.6 8.0 9.5 10.0 23.1 7.6 8.7 5.4 8.4 8.1 8.3 11.2 12.4 16.1 19.8 9.7 18.0 14.7 12.1 11.2 9.6 7.8 14.1 7.7 11.8 13.3 18.5 17.6 18.7 15.1 14.5 8.0 10.5 12.6 8.2 18.1 21.1 14.0 17.0 20.8 12.7 25.8 12.1 17.6 11.3 14.6 10.7 18.3 8.8 11.1 13.0 8.7 27.2 13.7 9.7 23.2 19.3 16.9 9.0 23.3 12.3 13.6 18.9 21.3 8.8 11.0 11.8 9.8 11.3 6.4 18.3 18.0 15.5 30.7 11.7 18.6 12.9 13.8 4.5 6.2 11.4 6.3 7.2 6.1 5.8 5.5 6.2 6.5 4.0 5.7 6.0 6.5 5.4 9.7 4.6 6.4 5.8 7.4 7.9 8.0 10.1 7.8 8.8 8.2 7.9 8.6 8.0 8.0 8.4 19.7 32.1 12.8 2.0 18.3 21.7 11.7 28.5 19.9 12.4 27.2 20.7 51.6 10.0 23.1 25.8 2.1 32.8 23.3 17.2 27.4 23.2 75.0 14.7 19.9 21.6 19.7 28.4 9.1 16.2 44.7 15.9 13.3 16.4 17.7 14.1 13.6 13.7 27.7 3.3 12.9 16.5 34.6 21.0 17.2 76.9 13.4 18.4 19.6 4.7 20.6 16.9 27.8 6.0 10.7 23.0 18.7 17.0 16.4 20.8 14.8 26.6 19.8 14.7 19.7 15.2 25.4 19.7 22.1 16.5 25.9 56.9 23.5 16.7 14.2 20.7 RBM20 ENSG00000203867 "RNA binding motif protein 20" Q5T481 10 110644336-110839468 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 40.8;pancreas: 20.2" "Cell type enriched" "Detected in many" 8 "Cardiomyocytes: 151.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 6.0;HEL: 5.2;K-562: 5.0;RH-30: 16.2;SH-SY5Y: 15.0;SuSa: 4.9;T-47d: 9.2" "Low region specificity" "Detected in single" "HPA035806, HPA070358" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytokinetic bridge" Yes No "Cluster 38: Heart - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Golgi apparatus" "Nucleoli, Cytokinetic bridge" "HPA035806: AB_10672097, HPA070358: " "unprognostic (2.43e-1)" "unprognostic (8.24e-3)" "unprognostic (5.81e-2)" "unprognostic (1.27e-2)" "unprognostic (1.03e-1)" "unprognostic (2.03e-2)" "unprognostic (2.75e-2)" "unprognostic (5.47e-3)" "unprognostic (1.33e-1)" "unprognostic (2.78e-2)" "unprognostic (4.14e-3)" "unprognostic (1.44e-1)" "unprognostic (2.39e-3)" "unprognostic (3.34e-1)" "unprognostic (3.35e-2)" "unprognostic (1.20e-1)" "unprognostic (6.46e-2)" 1.5 0.1 0.8 0.2 2.6 0.1 2.5 0.4 0.8 1.5 1.8 4.1 0.1 2.9 0.6 5.6 2.6 0.4 40.8 0.8 0.4 0.7 0.1 0.9 0.1 0.8 0.9 2.7 20.2 1.2 1.7 1.6 0.6 1.3 0.4 1.2 7.3 0.7 15.6 1.2 0.8 2.2 0.5 0.1 1.0 0.8 0.8 0.5 1.0 3.8 0.6 1.0 5.5 0.7 0.0 1.6 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.1 0.1 0.0 0.0 2.5 6.0 5.2 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 1.4 0.0 16.2 0.0 0.0 0.0 0.1 15.0 0.1 0.0 0.6 4.9 9.2 0.0 0.0 0.3 0.5 0.0 0.0 0.4 0.1 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.6 0.4 0.8 0.8 0.4 0.8 0.9 0.6 0.5 0.8 0.7 0.3 0.0 0.0 0.7 0.2 0.1 0.2 0.4 1.2 1.4 0.8 0.5 151.5 0.0 0.1 0.0 2.1 1.6 0.0 0.7 1.9 0.0 0.8 0.5 1.2 1.5 0.0 0.0 14.8 0.2 0.2 3.3 0.0 0.1 0.0 14.6 1.4 0.0 0.1 0.0 15.4 0.7 2.0 0.0 0.0 0.8 4.4 0.0 0.0 17.8 0.0 0.1 0.0 1.5 0.6 0.0 0.1 13.5 1.0 0.0 2.0 1.5 12.4 2.7 6.6 3.7 5.4 0.5 0.8 3.7 0.0 3.1 0.2 1.7 0.2 0.3 RBM34 KIAA0117 ENSG00000188739 "RNA binding motif protein 34" P42696 1 235131183-235161283 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028606 Approved Supported "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes No "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 11: Alveolar cells - Smell perception" Nucleoli "Nucleoplasm, Mitotic chromosome" "HPA028606: AB_10601494" "unprognostic (4.53e-2)" "unprognostic (3.64e-2)" "unprognostic (7.30e-2)" "unprognostic (3.68e-2)" "unprognostic (1.28e-1)" "unprognostic (2.32e-2)" "unprognostic (6.57e-4)" "unprognostic (2.98e-2)" "unprognostic (5.65e-3)" "unprognostic (2.02e-2)" "unprognostic (1.38e-1)" "unprognostic (1.13e-1)" "unprognostic (1.69e-8)" "unprognostic (8.50e-2)" "unprognostic (1.85e-1)" "unprognostic (8.73e-2)" "unprognostic (7.09e-4)" 12.2 10.3 11.7 15.0 12.5 35.5 17.0 12.1 13.7 10.0 12.3 12.4 17.9 11.5 15.6 13.9 10.9 12.2 15.5 11.8 12.6 17.1 14.8 11.9 23.2 13.3 12.5 12.8 13.1 9.2 8.7 13.2 13.1 12.0 14.1 6.3 19.9 7.4 19.7 18.2 15.8 11.6 13.1 12.7 14.3 21.3 12.5 16.3 15.6 12.3 20.6 15.7 9.6 13.5 28.6 20.9 23.8 28.8 17.9 33.3 52.8 29.3 24.6 29.4 30.1 26.9 33.7 49.4 29.9 21.0 22.1 40.5 29.0 28.9 28.2 44.4 47.8 35.7 17.0 20.1 35.1 60.4 34.5 28.0 33.2 26.5 19.6 26.5 26.8 50.5 54.5 23.7 38.7 18.0 49.9 48.3 65.3 43.8 15.8 48.0 23.2 57.3 29.5 22.7 26.2 47.1 39.2 27.0 66.4 17.0 55.2 63.5 21.0 26.2 23.0 36.1 59.9 27.8 47.5 47.4 30.8 38.0 40.8 113.9 36.0 44.1 46.1 42.5 55.6 74.1 53.0 59.8 37.2 54.5 49.0 57.4 18.3 58.2 46.4 59.5 77.5 51.5 11.7 12.5 12.1 13.7 11.8 12.6 13.3 12.5 13.1 13.1 12.5 13.5 4.3 19.2 12.8 12.1 11.9 3.2 10.0 7.3 10.2 2.6 6.3 3.7 3.4 7.2 9.1 3.7 10.4 6.2 19.3 4.1 5.9 6.6 7.2 3.2 5.1 6.9 7.8 3.8 10.6 6.2 4.5 10.3 4.6 6.0 23.4 8.0 6.1 3.6 3.3 0.0 11.5 2.7 8.2 5.4 3.2 7.9 4.1 7.1 3.6 15.9 9.4 4.0 23.7 10.1 11.9 8.6 9.6 5.7 10.2 5.3 5.3 12.8 10.7 5.7 0.0 5.0 4.4 7.1 5.3 8.0 3.8 6.2 16.2 3.3 4.5 7.7 RCOR2 ENSG00000167771 "REST corepressor 2" Q8IZ40 11 63911230-63917164 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 20.7;Excitatory neurons: 5.9;Extravillous trophoblasts: 4.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 35.7;NTERA-2: 47.0;SCLC-21H: 72.6;SH-SY5Y: 48.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021638 Uncertain Approved Nucleoplasm,Vesicles,Midbody Yes NA "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "Vesicles, Midbody" "HPA021638: AB_10960885" "unprognostic (1.96e-2)" "unprognostic (1.15e-1)" "unprognostic (4.10e-2)" "unprognostic (1.98e-3)" "unprognostic (3.10e-2)" "unprognostic (5.86e-2)" "unprognostic (2.33e-4)" "unprognostic (8.64e-2)" "unprognostic (1.46e-1)" "unprognostic (4.80e-2)" "unprognostic (1.67e-1)" "unprognostic (1.72e-3)" "unprognostic (2.62e-1)" "unprognostic (1.75e-1)" "unprognostic (3.51e-1)" "unprognostic (9.93e-2)" "unprognostic (6.06e-3)" 0.3 0.5 1.8 0.2 3.2 0.0 0.4 1.3 3.7 1.4 0.1 1.1 0.8 2.7 1.0 0.4 1.5 0.4 2.8 2.5 1.1 0.6 0.1 0.3 0.0 1.2 1.0 1.2 0.5 1.4 3.5 0.7 0.8 0.9 0.6 3.4 0.9 0.6 1.5 0.3 0.6 1.0 1.1 0.1 0.7 3.2 1.0 0.9 0.2 0.7 0.0 1.2 0.6 2.4 0.0 1.0 35.7 2.5 0.5 2.9 10.9 0.2 0.6 0.5 1.2 1.4 0.3 0.3 0.4 0.8 0.7 0.4 15.8 0.0 0.3 0.6 2.0 0.5 0.3 11.9 5.9 0.0 0.3 3.5 0.0 0.6 0.0 0.0 0.3 4.8 2.0 0.0 0.0 3.3 3.4 13.2 47.0 4.8 0.1 12.4 2.1 1.0 0.1 0.1 72.6 48.7 0.3 3.2 1.8 8.7 2.7 4.5 0.3 0.1 2.3 0.1 0.1 0.3 0.1 0.4 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 3.2 1.3 3.7 2.5 1.1 1.2 1.0 0.8 1.1 1.0 2.4 0.6 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 20.7 0.6 0.4 2.2 0.0 0.1 0.0 0.0 0.5 0.0 1.0 0.0 0.1 0.1 0.3 3.3 0.6 1.2 0.0 5.9 0.2 4.4 1.1 0.0 0.6 0.0 1.2 0.0 0.0 0.2 3.3 1.5 1.2 2.0 0.0 0.0 0.1 1.5 0.1 0.0 0.0 0.0 2.1 1.0 1.0 1.5 0.2 0.2 0.4 0.0 0.0 0.3 0.1 0.2 2.2 0.0 0.3 0.7 0.7 2.9 0.0 0.3 0.8 0.1 1.2 0.8 0.1 RDH8 "PRRDH, SDR28C2" ENSG00000080511 "Retinol dehydrogenase 8" Q9NYR8 19 10013249-10022279 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Sensory transduction, Vision" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 37 "retina: 114.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 39.3;Cone photoreceptor cells: 54.2;Early spermatids: 72.6;Muller glia cells: 22.1;Rod photoreceptor cells: 203.4" "Cancer enriched" "Detected in some" 4 "melanoma: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA064473 Approved "Nucleoplasm,Midbody ring,Cytosol" Yes NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Midbody ring, Cytosol" "HPA064473: " "unprognostic (4.12e-1)" "unprognostic (2.22e-2)" "unprognostic (1.08e-1)" "unprognostic (9.98e-3)" "unprognostic (4.58e-3)" "unprognostic (2.66e-1)" "unprognostic (1.45e-1)" "unprognostic (1.02e-1)" "unprognostic (3.86e-1)" "unprognostic (2.63e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 114.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.3 0.0 0.0 0.2 0.0 0.0 0.0 54.2 0.0 0.0 0.0 0.0 0.0 72.6 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 22.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 203.4 0.0 0.0 0.2 1.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 RINT1 "FLJ11785, RINT-1" ENSG00000135249 "RAD50 interactor 1" Q6NUQ1 7 105532169-105567677 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, ER-Golgi transport, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019875, HPA031646" Approved Approved "Golgi apparatus" Yes No "Cluster 40: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Golgi apparatus" "HPA019875: AB_1856283, HPA031646: AB_2673975" "unprognostic (1.58e-2)" "unprognostic (3.94e-2)" "unprognostic (9.00e-2)" "unprognostic (1.80e-1)" "unprognostic (2.50e-1)" "unprognostic (7.95e-2)" "unprognostic (4.68e-3)" "unprognostic (1.33e-2)" "unprognostic (4.96e-3)" "unprognostic (2.41e-1)" "unprognostic (8.72e-2)" "unprognostic (5.35e-2)" "unprognostic (8.75e-3)" "unprognostic (1.47e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.39e-5)" "unprognostic (1.76e-1)" 7.3 6.1 2.8 9.0 3.1 15.2 10.0 6.9 3.7 8.2 5.6 8.1 9.4 8.6 7.2 11.3 8.0 6.7 8.2 3.1 3.1 9.3 10.5 6.7 13.4 2.8 2.7 8.0 11.6 9.7 5.4 8.8 3.1 7.8 9.3 10.3 11.3 6.1 16.7 8.7 7.1 6.4 3.2 8.8 9.7 11.1 2.7 9.9 8.8 13.3 13.7 8.4 5.7 4.1 28.8 23.5 12.1 27.8 18.8 24.9 15.9 27.2 19.2 26.4 29.6 27.4 18.4 31.6 31.3 24.1 29.4 19.0 22.5 21.0 34.7 17.0 25.9 18.3 26.1 18.5 14.5 38.9 17.8 17.9 16.4 28.1 16.3 20.3 29.1 16.3 39.5 23.2 30.3 46.9 29.3 28.6 26.1 23.8 23.1 17.5 20.5 45.4 14.2 23.6 20.5 22.4 28.9 47.7 20.6 20.9 19.4 12.5 20.3 30.2 24.0 83.1 34.8 46.6 59.7 61.4 20.0 31.8 34.6 4.4 3.9 4.4 6.7 5.8 11.6 9.0 9.8 9.2 6.0 7.8 8.6 9.4 0.7 9.1 4.8 4.0 10.5 6.2 2.8 3.1 6.9 3.7 3.1 3.1 2.8 2.7 3.1 3.2 2.7 4.1 6.7 3.2 9.8 10.4 12.4 6.6 9.6 7.7 8.6 5.8 5.9 5.3 10.5 1.5 9.4 3.7 8.4 11.2 13.4 6.0 9.8 8.1 10.8 9.0 6.4 6.8 5.4 4.6 25.6 6.3 10.3 9.4 12.2 5.5 10.1 7.5 4.2 5.1 7.3 6.7 26.0 5.8 10.2 5.6 3.4 6.2 8.7 5.2 5.4 9.4 5.7 7.8 7.2 9.0 18.2 6.7 4.0 9.8 17.9 6.5 5.5 6.8 18.1 8.9 6.6 8.3 8.0 29.2 12.4 8.3 7.7 12.0 10.8 7.5 6.4 8.3 RLF "Zn-15L, ZNF292L" ENSG00000117000 "RLF zinc finger" Q13129 1 40161387-40240921 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054653, HPA057300" Uncertain Approved Nucleoplasm,Nucleoli Yes No "Cluster 42: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm Nucleoli "HPA054653: AB_2682557, HPA057300: AB_2683404" "unprognostic (1.71e-1)" "unprognostic (2.24e-2)" "unprognostic (6.46e-2)" "unprognostic (1.88e-2)" "unprognostic (6.78e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (1.75e-4)" "unprognostic (5.84e-2)" "unprognostic (3.43e-2)" "unprognostic (2.18e-2)" "unprognostic (2.60e-2)" "unprognostic (9.38e-2)" "prognostic unfavorable (7.68e-6)" "unprognostic (1.86e-1)" "unprognostic (2.59e-1)" "unprognostic (1.12e-1)" "unprognostic (4.69e-2)" 8.7 4.9 5.5 6.2 6.0 32.8 8.3 12.0 7.9 8.4 2.5 7.6 5.1 7.9 4.7 7.3 7.0 6.6 7.5 6.0 5.6 4.9 7.7 8.2 7.7 4.1 4.3 8.3 5.6 6.5 5.1 7.3 4.2 6.6 5.2 15.4 5.7 5.4 8.5 12.2 6.2 6.1 4.3 6.2 5.7 10.3 5.2 10.2 5.8 7.1 8.5 7.8 8.4 8.2 18.3 6.9 13.3 13.9 11.6 9.4 15.8 6.7 9.9 11.3 14.9 14.0 9.4 18.1 8.6 8.6 8.4 16.8 16.9 11.8 20.4 8.5 11.4 14.9 8.0 8.7 9.2 12.5 8.7 9.3 12.1 12.0 13.5 13.5 7.8 9.8 23.0 10.8 10.4 5.8 10.6 7.5 17.8 6.7 7.9 8.2 21.8 10.6 7.2 18.2 9.4 13.1 12.5 16.5 12.0 20.5 7.8 44.6 6.7 13.2 14.1 11.0 12.6 9.8 9.8 16.6 11.5 11.4 8.4 6.9 1.5 3.0 1.8 2.0 2.4 2.3 1.8 1.9 1.9 2.1 2.3 2.0 3.2 2.4 2.4 0.8 1.8 1.3 5.5 6.0 12.0 7.9 6.0 5.6 4.1 4.3 4.2 4.3 5.2 8.2 36.7 32.1 15.1 52.2 55.8 65.6 50.3 12.7 30.7 17.8 25.5 18.4 16.9 2.8 23.9 3.7 16.7 8.9 40.6 10.4 5.9 13.8 41.3 43.8 41.6 24.9 20.2 11.3 87.1 6.7 10.6 34.9 29.6 56.0 26.6 23.0 16.1 9.0 9.7 26.9 84.7 8.8 14.2 13.8 45.2 8.7 9.0 39.9 17.8 60.9 17.5 14.1 9.2 71.9 89.0 10.1 15.5 7.9 44.6 28.7 8.9 5.5 26.0 17.2 13.1 52.8 36.1 32.2 20.8 29.3 61.1 17.2 45.8 17.0 10.8 33.0 RMDN2 "FAM82A, FAM82A1, FLJ32954, RMD2" ENSG00000115841 "Regulator of microtubule dynamics 2" Q96LZ7 2 37923187-38067142 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 42.5" "Group enriched" "Detected in many" 4 "Early spermatids: 270.4;Late spermatids: 163.5;Theca cells: 77.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034705, HPA034706" Enhanced Supported "Golgi apparatus,Mitotic spindle,Cytosol" Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Mitotic spindle, Cytosol" "Golgi apparatus" "HPA034705: AB_2674292, HPA034706: AB_10696362" "unprognostic (1.34e-1)" "unprognostic (2.61e-1)" "unprognostic (4.03e-2)" "unprognostic (1.71e-3)" "unprognostic (2.49e-2)" "unprognostic (1.76e-1)" "unprognostic (3.06e-2)" "prognostic favorable (2.63e-4)" "unprognostic (7.85e-2)" "unprognostic (9.96e-2)" "unprognostic (7.50e-2)" "unprognostic (1.94e-1)" "unprognostic (2.88e-2)" "unprognostic (5.08e-3)" "unprognostic (1.20e-1)" "unprognostic (4.34e-3)" "unprognostic (3.34e-1)" 4.6 42.5 3.8 4.1 3.5 3.4 5.3 4.8 4.5 7.7 2.9 12.4 8.4 5.1 9.2 3.4 3.9 6.2 4.4 4.1 2.6 7.8 29.2 11.3 4.6 3.9 2.6 2.8 4.1 3.2 3.0 3.9 2.6 7.2 10.6 4.2 3.7 12.8 5.1 2.9 13.9 5.8 3.0 20.0 4.4 21.7 3.6 5.9 5.4 3.2 2.9 4.3 3.5 3.7 3.3 4.7 2.6 1.8 10.4 11.4 1.5 7.0 9.3 3.6 3.2 1.1 10.9 2.2 2.8 9.9 2.2 3.5 0.8 5.1 4.9 5.0 3.0 3.6 1.6 3.1 5.3 0.0 3.8 16.2 4.6 4.5 0.7 5.4 2.0 1.8 4.4 2.1 6.8 1.3 0.9 4.5 5.1 6.5 3.8 0.0 0.8 0.6 9.0 2.7 2.1 7.5 5.7 0.7 7.3 2.2 1.1 5.9 3.8 4.4 5.1 2.5 2.6 3.8 7.7 4.6 5.4 1.1 4.6 0.0 2.8 0.7 2.0 4.6 3.1 4.1 1.0 1.3 1.8 2.3 1.0 2.2 2.7 3.7 3.5 3.4 0.1 1.4 3.8 3.5 4.8 4.5 4.1 2.6 3.9 2.6 2.6 3.0 3.6 3.7 3.4 28.9 29.6 25.1 6.5 2.4 6.8 16.3 8.6 3.5 1.9 4.2 5.3 11.5 20.0 5.5 2.1 2.1 6.0 20.9 7.9 5.4 270.4 3.7 11.8 4.6 4.8 3.0 33.8 3.8 1.0 9.2 2.6 3.1 15.8 13.1 5.3 15.5 4.7 5.0 24.5 11.4 6.1 6.3 1.7 163.5 9.3 4.8 5.4 19.7 4.4 4.7 6.2 39.2 7.1 2.5 6.1 6.0 1.8 2.2 29.6 6.7 10.2 2.6 6.6 6.4 5.1 9.4 4.8 1.7 2.4 0.8 3.9 77.6 15.2 2.3 RMDN3 "FAM82A2, FAM82C, FLJ10579, PTPIP51, RMD3" ENSG00000137824 "Regulator of microtubule dynamics 3" Q96TC7 15 40735884-40755851 "Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 110.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009975, HPA074840" Supported Enhanced "Cytokinetic bridge,Mitochondria" Yes No 42000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 45: Intestine - Brush border" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" Mitochondria "Cytokinetic bridge" "HPA009975: AB_1078811, HPA074840: " "unprognostic (2.54e-2)" "unprognostic (3.53e-1)" "unprognostic (2.35e-2)" "unprognostic (3.97e-3)" "unprognostic (1.50e-1)" "unprognostic (2.50e-3)" "unprognostic (2.78e-2)" "unprognostic (2.54e-2)" "unprognostic (1.73e-1)" "unprognostic (1.68e-1)" "unprognostic (2.78e-2)" "unprognostic (5.94e-3)" "prognostic favorable (6.70e-8)" "unprognostic (1.71e-2)" "unprognostic (1.32e-1)" "unprognostic (5.79e-3)" "unprognostic (2.04e-3)" 30.1 22.7 37.2 16.2 40.2 24.1 26.7 38.4 48.6 18.0 31.2 18.1 43.8 15.9 5.4 22.6 18.8 16.7 16.4 36.3 36.1 18.4 37.0 36.5 15.6 40.2 38.6 17.2 27.2 36.3 10.9 19.4 36.0 17.2 9.0 6.7 33.3 15.4 20.7 21.1 51.7 11.2 37.7 13.0 21.5 13.8 42.9 15.0 19.9 14.1 8.4 20.3 17.6 41.2 19.7 17.7 21.0 35.9 19.2 17.2 36.3 50.2 19.8 34.9 25.6 63.7 21.7 16.7 65.0 27.0 26.0 66.3 26.9 37.3 3.7 44.2 33.1 53.6 51.4 31.6 62.9 36.4 41.1 30.9 34.0 25.2 23.9 16.3 24.8 32.6 57.4 44.9 15.1 40.0 27.7 23.6 16.7 52.7 34.6 42.6 25.1 38.9 28.8 32.7 49.8 18.1 39.9 53.4 19.5 8.2 41.6 39.1 37.3 37.8 27.0 51.1 42.5 34.0 42.7 26.7 26.8 38.2 42.2 4.0 13.2 5.5 28.2 17.8 25.0 16.0 20.6 26.0 14.4 13.7 15.9 17.3 2.1 65.1 22.3 54.2 20.3 26.6 37.2 40.2 38.4 48.6 36.3 36.1 40.2 38.6 36.0 37.7 42.9 41.2 20.1 32.1 28.1 18.6 11.0 15.7 16.4 26.9 15.9 20.0 21.0 13.6 8.1 15.7 27.8 18.4 4.2 44.4 22.4 17.2 1.9 27.7 2.8 20.7 17.8 18.1 4.9 42.7 23.5 22.0 28.5 17.8 13.7 22.0 19.0 8.6 17.5 36.4 110.7 18.5 18.2 12.3 26.4 14.7 10.4 3.4 16.8 21.0 19.6 8.4 11.7 21.6 43.3 16.1 21.8 21.8 16.7 14.3 18.0 17.3 77.6 14.5 29.3 17.3 6.6 22.2 16.0 40.4 40.4 21.9 11.9 62.8 18.3 16.7 21.4 23.1 RNF167 DKFZP566H073 ENSG00000108523 "Ring finger protein 167" Q9H6Y7 17 4940008-4945222 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049810 Approved Approved "Vesicles,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Vesicles, Cytosol" "Mitotic spindle, Centriolar satellite" "HPA049810: AB_2680894" "unprognostic (1.13e-1)" "unprognostic (5.12e-2)" "unprognostic (2.29e-3)" "unprognostic (1.63e-2)" "unprognostic (3.43e-2)" "unprognostic (7.32e-2)" "unprognostic (2.18e-1)" "unprognostic (6.77e-2)" "unprognostic (7.46e-2)" "unprognostic (2.07e-2)" "prognostic favorable (2.03e-6)" "unprognostic (2.16e-1)" "prognostic favorable (4.47e-4)" "unprognostic (7.62e-2)" "unprognostic (1.93e-1)" "unprognostic (3.26e-1)" "unprognostic (1.12e-1)" 75.0 110.6 141.9 53.0 146.7 69.0 73.1 146.4 179.9 93.2 138.6 111.5 66.6 94.9 76.4 122.1 84.3 45.3 131.8 141.5 146.4 106.7 184.2 77.5 64.5 146.3 145.4 87.4 115.1 105.8 96.8 50.7 146.3 95.0 65.7 98.1 92.5 70.5 152.9 127.8 100.5 52.8 142.4 113.8 111.8 110.6 150.3 98.1 93.4 94.2 71.6 106.7 90.4 153.3 102.6 143.1 61.1 73.7 132.8 68.7 92.7 63.4 76.1 119.7 93.4 96.2 43.3 71.5 120.3 93.5 63.9 147.5 103.2 114.8 86.1 74.5 166.1 121.9 164.4 94.9 100.6 59.0 245.0 79.6 176.5 129.8 116.2 74.6 77.2 101.0 49.9 237.5 96.2 66.3 92.8 70.6 75.4 102.0 86.8 62.8 61.9 91.5 137.3 77.4 49.2 61.1 56.0 92.9 81.9 83.1 87.3 55.9 49.5 76.6 48.3 66.8 119.3 79.5 88.0 23.7 98.4 80.6 77.9 108.4 88.8 236.9 195.3 94.0 153.4 100.4 148.0 195.7 73.9 98.7 103.2 152.2 219.8 118.8 117.7 75.9 153.0 177.0 141.9 146.7 146.4 179.9 141.5 146.4 146.3 145.4 146.3 142.4 150.3 153.3 36.9 0.0 3.9 12.4 54.3 68.6 44.4 65.8 51.8 43.2 56.6 44.7 15.8 77.2 38.9 49.7 20.9 120.1 64.7 65.2 56.7 78.5 59.6 29.8 25.1 36.4 31.8 60.6 11.3 66.7 139.7 36.3 36.2 32.2 14.0 26.3 45.7 95.1 58.4 18.5 11.2 45.7 65.1 41.3 43.6 86.5 48.7 36.1 39.2 6.5 53.1 46.9 114.4 10.1 17.9 60.7 44.9 53.8 59.1 32.6 108.2 64.0 31.1 32.3 39.5 28.4 35.1 127.1 106.7 61.4 83.3 125.2 82.5 37.2 59.6 48.0 RNF187 "RACO-1, RACO1" ENSG00000168159 "Ring finger protein 187" Q5TA31 1 228487382-228496188 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Theca cells: 217.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-266/70: 189.0" "Low region specificity" "Detected in all" HPA030098 Approved Supported Nucleoplasm,Cytosol Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 29: U-266 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Cytosol" "HPA030098: AB_10602923" "unprognostic (4.84e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (2.83e-4)" "unprognostic (4.90e-3)" "unprognostic (1.13e-1)" "unprognostic (2.93e-2)" "unprognostic (3.46e-2)" "unprognostic (2.53e-1)" "unprognostic (1.36e-1)" "unprognostic (5.66e-3)" "unprognostic (1.37e-1)" "unprognostic (1.55e-1)" "unprognostic (2.92e-3)" "unprognostic (1.59e-1)" "unprognostic (9.76e-2)" "unprognostic (1.76e-1)" "unprognostic (2.32e-2)" 26.8 66.6 16.2 7.5 16.2 11.3 25.8 14.8 24.3 40.5 3.4 28.1 8.6 31.8 4.3 59.1 28.7 5.6 35.4 15.9 16.9 40.7 52.0 23.6 7.3 19.4 15.2 39.3 34.5 22.5 47.7 5.5 18.4 33.5 3.7 9.0 39.7 8.2 64.2 45.0 22.5 5.6 15.6 37.0 27.6 20.8 18.5 8.5 36.1 19.8 6.1 29.9 41.2 19.8 26.7 23.1 14.8 28.9 16.8 12.5 26.6 21.5 17.3 15.6 12.7 12.8 19.2 65.9 43.1 28.9 11.4 20.9 19.1 22.1 5.8 25.9 28.5 20.8 13.2 12.6 46.1 22.1 34.4 20.4 44.7 11.6 15.8 18.3 14.0 52.6 35.6 115.2 12.4 17.7 35.2 20.8 30.7 19.1 24.0 27.8 12.5 61.5 11.4 17.2 29.9 30.0 21.9 44.1 62.3 4.3 34.6 50.2 27.8 18.3 16.9 19.6 19.3 189.0 56.7 36.4 46.7 22.7 28.7 0.0 0.5 3.6 0.6 1.0 0.7 0.5 0.7 1.0 0.6 1.0 0.6 0.7 0.1 0.4 1.4 0.7 0.6 0.3 16.2 16.2 14.8 24.3 15.9 16.9 19.4 15.2 18.4 15.6 18.5 19.8 54.0 25.6 15.5 8.1 47.2 36.2 42.9 10.6 38.7 85.2 59.5 58.5 70.8 65.8 14.2 40.5 18.8 19.7 52.2 39.8 113.5 15.2 0.8 35.5 47.2 32.1 40.0 118.4 16.6 24.5 27.1 54.4 34.7 32.0 44.5 45.0 41.7 67.4 27.4 55.5 17.2 36.6 2.0 40.1 30.5 4.2 24.5 35.8 39.2 12.2 29.7 145.3 62.8 7.1 12.6 21.4 23.4 25.9 35.4 44.0 32.9 126.4 10.3 47.7 19.7 52.2 38.4 4.2 21.5 57.0 55.3 17.6 54.6 217.5 38.6 31.7 RNF41 "NRDP1, SBBI03" ENSG00000181852 "Ring finger protein 41" Q9H4P4 12 56202179-56221933 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Autophagy, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 92.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016812 Approved Approved "Nucleoplasm,Nuclear bodies,Midbody ring" Yes NA "Cluster 2: Granulocytes - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Nuclear bodies" "Midbody ring" "HPA016812: AB_1856370" "unprognostic (1.14e-2)" "unprognostic (6.30e-2)" "unprognostic (4.04e-2)" "unprognostic (6.86e-2)" "unprognostic (9.59e-2)" "unprognostic (8.22e-2)" "prognostic unfavorable (6.49e-4)" "unprognostic (6.93e-2)" "unprognostic (4.18e-2)" "unprognostic (1.67e-1)" "unprognostic (5.80e-2)" "unprognostic (5.90e-2)" "prognostic favorable (2.52e-5)" "unprognostic (1.64e-1)" "unprognostic (1.65e-1)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" 32.2 24.6 22.5 18.0 23.3 19.6 21.4 15.7 23.8 21.2 13.0 23.8 12.4 22.3 13.2 23.1 24.3 25.5 32.7 24.6 24.8 19.7 15.1 23.8 23.4 16.8 19.1 22.9 23.0 27.4 22.8 21.3 21.2 33.9 19.0 23.8 15.0 20.7 34.0 15.0 16.1 28.5 15.3 20.6 17.0 15.9 23.5 26.5 28.6 40.8 25.1 28.2 17.0 19.2 21.6 32.6 34.7 55.2 71.0 51.3 25.8 70.8 69.5 62.2 50.2 40.0 27.6 41.6 36.7 60.2 20.6 24.3 47.4 34.1 44.9 43.8 25.7 55.8 22.3 23.2 148.3 61.6 58.3 66.0 78.6 52.0 91.0 81.7 61.3 34.5 40.4 41.3 35.1 34.9 35.6 27.6 41.9 21.6 37.8 38.2 24.9 25.3 33.3 31.3 62.9 38.1 61.9 35.0 55.4 34.3 49.2 71.3 37.3 31.3 32.9 40.6 27.8 29.6 36.6 37.5 37.2 36.4 38.0 59.1 27.2 99.9 27.6 26.7 24.9 50.3 23.0 24.3 30.6 55.1 23.4 24.0 36.2 33.1 28.3 23.7 29.4 31.0 22.5 23.3 15.7 23.8 24.6 24.8 16.8 19.1 21.2 15.3 23.5 19.2 18.9 44.8 22.6 11.1 42.2 12.0 19.9 8.6 19.9 30.7 22.2 21.1 24.6 24.3 18.8 16.5 22.9 15.2 17.0 10.2 17.6 15.3 92.8 13.9 14.2 20.7 20.4 11.1 15.0 21.3 18.5 22.7 9.7 14.2 25.9 16.8 30.0 16.7 19.3 28.6 15.7 13.9 8.2 34.9 22.7 58.0 23.0 25.0 7.2 9.4 33.5 26.2 15.5 14.6 12.3 20.8 20.3 25.9 14.6 33.5 12.3 19.6 18.0 18.3 26.3 23.2 27.4 10.4 14.2 14.4 16.6 16.8 16.6 17.1 14.3 23.1 RPF2 "bA397G5.4, BXDC1, FLJ21087" ENSG00000197498 "Ribosome production factor 2 homolog" Q9H7B2 6 110982015-111028263 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-2197: 234.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035475 Supported Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: U-2197 - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA035475: AB_10669861" "unprognostic (2.85e-3)" "unprognostic (2.19e-2)" "unprognostic (6.00e-2)" "unprognostic (2.90e-3)" "unprognostic (4.45e-1)" "prognostic unfavorable (2.04e-4)" "prognostic unfavorable (2.25e-4)" "unprognostic (1.14e-1)" "unprognostic (1.12e-1)" "unprognostic (1.99e-1)" "unprognostic (8.43e-2)" "unprognostic (9.16e-2)" "prognostic unfavorable (2.07e-6)" "unprognostic (2.39e-2)" "unprognostic (2.35e-1)" "unprognostic (1.28e-1)" "unprognostic (1.86e-1)" 16.4 12.2 6.6 9.5 7.4 10.8 14.9 7.3 8.7 12.9 7.2 11.9 6.6 11.2 5.4 15.2 12.5 9.1 15.3 7.0 7.1 15.8 17.2 9.7 10.4 6.9 6.9 13.2 19.9 9.7 8.1 10.2 7.0 11.4 8.8 5.6 9.9 7.1 22.2 13.9 8.1 8.1 6.9 9.3 11.7 13.5 7.1 7.6 13.0 14.0 10.9 15.3 12.5 7.9 23.3 16.6 12.7 50.5 26.4 34.7 32.6 32.5 23.6 32.3 32.6 39.2 18.5 50.2 29.4 22.8 38.8 27.0 51.5 37.6 84.2 19.4 38.7 29.5 14.2 27.4 35.9 45.9 16.6 26.5 31.4 46.5 83.5 20.3 24.9 22.1 99.0 29.9 52.2 23.4 39.2 45.5 45.2 37.7 20.2 40.2 22.4 43.6 37.4 22.9 20.3 28.7 14.1 23.7 61.3 16.8 18.8 47.3 17.5 24.7 21.2 234.1 81.4 13.4 22.0 65.0 36.4 60.8 55.2 0.2 4.4 0.7 4.1 5.5 8.5 6.6 6.1 5.0 5.8 5.7 6.8 7.0 0.3 8.8 3.5 5.8 5.0 4.0 6.6 7.4 7.3 8.7 7.0 7.1 6.9 6.9 7.0 6.9 7.1 7.9 40.0 19.2 26.9 6.5 25.0 78.4 119.6 90.1 35.9 14.1 33.6 52.3 71.9 47.1 67.6 18.4 0.0 44.9 18.0 15.8 68.4 48.2 105.7 49.8 57.6 35.2 11.4 26.1 15.7 47.4 53.8 50.0 17.3 60.9 46.2 18.9 23.6 83.6 56.0 18.5 14.0 30.3 36.7 27.7 19.5 32.1 34.5 28.2 37.4 5.6 21.8 21.0 19.6 9.0 13.5 42.2 18.7 27.1 18.8 80.4 15.2 87.2 55.0 8.9 13.1 61.7 49.9 76.8 28.4 33.0 66.2 34.6 22.9 29.8 44.0 70.2 RPL4 L4 ENSG00000174444 "Ribosomal protein L4" P36578 15 66498015-66524532 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034600 Uncertain Approved "Nucleoli,Nuclear bodies,Endoplasmic reticulum,Cytosol" Yes No 1300000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "Nucleoli, Nuclear bodies" "HPA034600: AB_10601483" "unprognostic (1.51e-2)" "unprognostic (3.77e-1)" "unprognostic (6.02e-2)" "unprognostic (3.68e-2)" "unprognostic (6.23e-3)" "unprognostic (1.03e-1)" "unprognostic (1.90e-2)" "unprognostic (3.20e-2)" "unprognostic (3.73e-1)" "unprognostic (2.85e-1)" "unprognostic (1.56e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (5.20e-5)" "unprognostic (1.27e-1)" "unprognostic (5.60e-2)" "unprognostic (4.63e-2)" "unprognostic (2.27e-1)" 831.6 565.7 367.7 738.6 404.0 1928.0 2030.6 377.1 545.7 1385.7 370.7 970.8 451.2 1276.0 1088.2 1289.4 1454.2 776.9 914.1 385.6 388.6 751.5 914.9 666.3 1630.2 376.4 380.9 3022.1 1740.5 954.0 504.0 746.1 386.6 709.1 1143.5 350.6 1234.8 1092.1 1314.7 1327.1 507.9 1353.5 383.2 776.9 643.8 296.4 373.4 1883.4 1289.5 1921.7 2451.3 1322.4 782.5 406.8 1192.9 2343.4 973.0 1646.3 4272.4 7697.6 1710.1 1416.1 2899.7 2143.0 1648.1 2611.3 2025.2 4676.6 1572.3 3396.6 1011.9 2105.0 7026.5 5476.3 2352.2 1301.4 4208.3 2872.9 1955.7 2201.2 6007.7 3042.0 1376.1 7627.4 6980.3 2334.4 9237.8 2620.8 3489.1 2180.2 2682.6 1785.2 3252.1 1956.0 2044.2 1348.1 2136.9 2634.2 1661.9 2256.2 2213.4 4588.3 2958.1 2321.4 1718.4 1794.6 872.3 2447.5 3515.4 2022.2 1812.5 4303.4 2059.2 1111.1 1662.1 1048.4 2297.9 1736.5 2937.8 3118.9 1368.2 4015.4 1281.7 46.4 455.3 62.2 359.4 370.9 668.1 711.1 698.6 506.5 586.8 644.5 888.5 721.6 26.9 478.1 361.3 372.8 589.8 1758.0 367.7 404.0 377.1 545.7 385.6 388.6 376.4 380.9 386.6 383.2 373.4 406.8 393.9 451.9 1004.9 28.1 1553.4 2423.4 2769.6 2082.8 1295.3 122.6 1594.0 1140.4 403.3 760.7 1165.2 342.1 81.3 2059.9 1055.8 364.9 1651.3 1162.8 672.5 337.9 821.0 840.2 761.1 1195.8 26.2 2141.0 3735.7 879.7 467.9 430.0 945.5 899.2 711.0 715.5 1211.2 40.4 23.9 1089.8 636.8 1281.3 2031.3 1392.4 1334.0 991.6 1088.5 27.2 1920.9 417.7 1196.8 15.1 30.0 1239.9 737.1 996.0 1019.5 2031.3 370.6 1572.3 603.9 169.9 460.2 1196.4 934.7 376.4 454.9 1632.1 2583.2 2398.3 1289.5 1184.6 1371.2 2628.6 RPL6 "L6, TAXREB107, TXREB1" ENSG00000089009 "Ribosomal protein L6" Q02878 12 112405189-112418838 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060903, HPA068418" Approved Approved "Microtubules,Cytokinetic bridge" Yes No 620000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Microtubules, Cytokinetic bridge" "HPA060903: AB_2732653, HPA068418: AB_2685987" "unprognostic (5.95e-2)" "unprognostic (1.31e-1)" "unprognostic (1.40e-1)" "unprognostic (5.49e-2)" "unprognostic (1.10e-2)" "unprognostic (2.50e-1)" "unprognostic (1.02e-2)" "unprognostic (3.74e-1)" "unprognostic (5.63e-2)" "unprognostic (1.07e-2)" "unprognostic (4.19e-3)" "unprognostic (2.52e-2)" "prognostic unfavorable (6.95e-4)" "unprognostic (2.45e-1)" "unprognostic (2.40e-2)" "unprognostic (3.38e-2)" "unprognostic (5.90e-2)" 1199.2 1080.7 788.0 937.3 801.7 2387.8 1856.5 776.8 1063.3 1357.1 828.3 1249.1 789.1 1236.7 1570.4 1485.5 1241.3 734.2 856.8 756.3 814.1 985.6 1026.1 803.0 1847.2 805.2 807.2 2777.7 1984.2 1103.8 1049.8 763.3 801.3 1017.4 1222.4 531.8 1632.2 850.0 1451.0 1598.1 946.0 1018.7 822.2 1015.0 1214.8 279.2 808.0 1815.8 1223.2 1298.0 2204.7 1349.1 1216.0 818.0 1973.8 1887.6 2227.1 2264.4 2725.6 4486.8 2932.4 1843.2 2670.8 2471.8 1408.6 2975.9 1213.3 4225.2 1547.6 2008.9 962.8 1881.4 2395.5 3288.1 2456.2 1682.6 3199.4 2274.7 1590.4 2693.3 2854.8 4103.6 1708.4 4171.2 4542.3 1876.9 4294.7 4571.2 2818.5 2754.1 3060.8 1134.5 2888.4 2727.7 3013.0 6699.3 3096.5 4209.0 2233.7 2731.0 2375.5 4144.9 3118.1 3283.8 2050.1 2651.9 1297.5 3446.9 3342.3 2007.3 3621.2 4189.6 1657.8 1215.8 1484.2 1572.8 2110.7 1542.6 2549.7 3377.6 1573.3 2948.5 1861.4 730.3 2260.1 463.1 2285.0 1851.6 3814.8 3463.8 3465.4 2972.5 2896.3 3116.2 3751.8 3251.5 262.6 2839.0 1688.0 3372.7 3027.9 7777.8 788.0 801.7 776.8 1063.3 756.3 814.1 805.2 807.2 801.3 822.2 808.0 818.0 1483.8 798.0 1587.2 31.0 3121.1 3145.3 3907.2 3373.8 2996.4 271.4 3790.3 6493.7 262.3 1818.7 1733.0 636.4 137.6 3077.0 2809.4 731.3 3502.2 2270.2 414.6 1133.8 2774.3 1661.9 1388.1 1929.0 42.6 3043.9 4721.2 1695.5 1135.6 1287.6 1290.2 1743.7 1854.3 1727.8 1880.0 121.1 48.2 2036.2 1112.9 2566.7 2790.5 714.3 2849.7 1964.8 1899.7 30.9 3399.6 854.8 2699.3 34.7 48.9 2582.7 1646.1 1589.9 2173.6 3165.2 1095.4 3376.3 776.7 412.3 927.0 2550.9 1835.3 376.5 461.6 3977.5 3650.1 3068.7 2710.6 2783.0 2512.8 3577.6 RPLP2 "D11S2243E, LP2, MGC71408, P2, RPP2" ENSG00000177600 "Ribosomal protein lateral stalk subunit P2" P05387 11 809965-812880 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053635, HPA075365" Approved Approved "Nuclear speckles,Mitotic spindle,Cytosol" "Intracellular and membrane" Yes NA 2900000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 32: Non-specific - Translation" "Nuclear speckles, Cytosol" "Mitotic spindle" "HPA053635: AB_2682212, HPA075365: " "unprognostic (6.98e-3)" "unprognostic (2.21e-1)" "unprognostic (4.57e-2)" "unprognostic (8.63e-2)" "unprognostic (2.30e-2)" "unprognostic (2.39e-1)" "prognostic unfavorable (9.14e-4)" "unprognostic (1.63e-1)" "unprognostic (2.98e-1)" "unprognostic (1.93e-1)" "unprognostic (2.08e-1)" "unprognostic (2.99e-1)" "prognostic unfavorable (2.19e-6)" "unprognostic (6.52e-2)" "unprognostic (1.67e-1)" "unprognostic (1.16e-1)" "unprognostic (3.31e-2)" 2013.7 831.3 1119.2 993.1 1162.5 2166.9 1656.6 1099.7 1368.9 1256.2 1084.1 1277.1 1016.8 930.2 701.6 1241.3 1240.4 564.0 869.3 1057.5 1116.3 885.0 657.0 851.0 1924.7 1138.0 1095.8 2092.8 2087.8 545.7 595.5 830.9 1154.3 925.8 887.8 180.9 1908.3 775.7 1802.7 1760.4 1191.7 624.4 1204.8 1543.8 1006.0 377.6 1167.5 1545.7 785.0 936.1 1715.4 1075.5 1137.9 1217.7 2773.5 2229.6 1070.4 1864.1 2343.2 2458.2 2389.5 1728.2 1285.0 2090.8 1638.4 3307.6 2218.5 3851.6 1225.0 1629.9 1107.9 2546.7 1786.2 2778.3 836.3 1713.6 8117.9 1901.7 1416.9 3996.4 2837.3 3540.8 1905.4 3393.9 4684.6 764.1 2182.7 1860.8 2111.9 2798.2 3432.2 2040.5 1317.9 2656.6 2969.5 6002.3 3188.8 3394.5 6045.3 3345.1 1465.6 4369.9 1759.0 1281.0 2222.2 3142.1 1118.5 2825.8 3582.4 885.1 1198.9 3577.2 1881.2 1142.3 1393.9 964.1 1981.6 3838.4 3778.8 3419.3 1790.5 2952.3 1340.6 1565.3 3908.1 1299.1 4402.2 3129.1 6208.3 10718.3 8296.0 6323.4 4273.6 9867.1 10158.6 8083.9 529.9 4310.4 2525.7 5882.9 5140.5 13330.7 1119.2 1162.5 1099.7 1368.9 1057.5 1116.3 1138.0 1095.8 1154.3 1204.8 1167.5 1217.7 1311.8 1067.3 1685.0 16.3 5889.9 6113.3 6658.4 2808.0 2619.1 206.2 5955.7 4736.9 638.4 2505.0 1972.2 1601.9 79.2 5046.4 3469.2 2296.4 2592.4 3688.3 1403.0 1105.9 2434.1 2724.8 2370.2 3482.2 18.6 7413.9 8045.8 2074.3 1401.2 1787.6 1721.9 1543.2 4028.6 3068.9 4514.0 146.4 17.8 5925.5 870.8 5458.4 6404.8 3133.4 6393.4 3169.4 2986.4 27.2 5854.8 1052.2 5787.9 6.0 19.0 5201.1 4547.7 2821.7 2403.4 6640.3 4473.8 4234.1 900.4 235.5 1991.9 3688.9 2346.3 1123.1 2093.1 4264.4 7887.4 5841.1 4889.3 1629.7 6189.1 7014.0 RRM2 "C2orf48, FLJ25102" ENSG00000171848 "Ribonucleotide reductase regulatory subunit M2" P31350 2 10120698-10211725 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "DNA replication" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 44.2;esophagus: 18.4;intestine: 19.7;lymphoid tissue: 58.1" "Group enriched" "Detected in many" 4 "Erythroid cells: 214.0;Extravillous trophoblasts: 254.1;Plasma cells: 248.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056994 Enhanced Supported Cytosol Yes Yes 13000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA056994: AB_2683304" "unprognostic (2.10e-2)" "unprognostic (1.62e-1)" "unprognostic (6.40e-3)" "unprognostic (4.42e-3)" "unprognostic (5.70e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (1.39e-5)" "unprognostic (1.04e-3)" "unprognostic (6.67e-3)" "unprognostic (4.53e-2)" "prognostic unfavorable (1.62e-4)" "unprognostic (5.11e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.05e-2)" "unprognostic (2.24e-1)" "unprognostic (1.38e-1)" "unprognostic (2.09e-2)" 1.5 1.3 0.3 12.4 0.3 44.2 2.9 0.5 0.4 3.0 1.9 14.2 9.4 2.2 0.7 18.4 0.8 1.1 0.5 0.3 0.3 0.9 3.2 2.4 35.5 0.4 0.4 0.3 1.1 0.3 0.2 4.6 0.4 0.9 19.7 0.2 2.1 0.5 0.1 3.7 7.5 6.1 0.3 11.1 6.0 2.9 0.8 58.1 0.9 0.1 37.6 6.0 4.6 0.5 110.2 25.0 127.1 49.9 7.4 22.5 116.8 209.2 128.6 170.2 187.9 70.8 59.1 114.4 9.5 88.6 151.1 55.0 188.0 136.6 198.0 210.7 41.8 146.3 52.1 105.1 0.8 146.7 87.4 8.1 3.4 234.6 16.2 27.7 103.3 110.4 63.4 328.6 214.3 57.1 167.3 90.9 83.0 133.3 103.6 87.6 187.0 67.8 87.1 62.7 67.7 56.2 198.0 116.6 17.3 51.8 69.2 31.4 57.6 93.1 125.1 66.9 289.6 212.1 184.9 195.9 51.0 134.4 107.7 0.3 0.1 0.1 1.2 0.0 0.0 0.1 0.3 0.8 0.1 0.1 0.1 0.4 0.4 0.8 0.0 0.1 0.2 0.2 0.3 0.3 0.5 0.4 0.3 0.3 0.4 0.4 0.4 0.3 0.8 0.5 0.2 3.2 1.5 0.0 25.0 10.5 3.0 9.2 1.2 0.0 3.9 4.4 1.4 1.5 2.3 0.0 0.0 42.3 5.6 12.9 1.9 1.2 3.9 2.2 3.5 4.2 0.0 214.0 0.1 0.0 254.1 11.2 11.7 3.6 5.7 12.2 3.9 3.7 47.9 0.0 0.0 26.9 2.0 7.2 8.8 6.8 0.3 5.0 0.0 1.0 0.0 0.0 7.2 0.0 0.0 0.5 0.3 0.4 248.0 1.5 2.4 2.1 4.6 0.0 0.0 0.2 14.6 22.9 34.0 51.5 1.6 48.7 11.9 1.2 36.7 5.6 RRP1 "D21S2056E, NNP-1, Nop52, RRP1A" ENSG00000160214 "Ribosomal RNA processing 1" P56182 21 43789513-43805293 "Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016818, HPA018166" Approved Enhanced "Nucleoli,Mitotic chromosome" Yes No "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Mitotic chromosome" "HPA016818: AB_1854561, HPA018166: AB_1854562" "unprognostic (5.38e-2)" "unprognostic (3.48e-1)" "unprognostic (3.43e-1)" "unprognostic (2.53e-2)" "unprognostic (9.44e-2)" "unprognostic (1.13e-2)" "unprognostic (7.69e-3)" "unprognostic (1.26e-1)" "unprognostic (7.63e-3)" "unprognostic (9.42e-2)" "unprognostic (6.94e-2)" "unprognostic (5.25e-2)" "prognostic unfavorable (6.29e-5)" "unprognostic (1.13e-1)" "unprognostic (9.21e-3)" "unprognostic (2.64e-1)" "unprognostic (1.88e-1)" 8.0 8.2 8.0 6.5 8.7 5.3 7.3 7.4 10.2 6.9 4.8 6.4 5.0 7.1 3.3 16.0 6.4 4.0 7.0 9.2 7.2 7.6 13.0 5.3 8.1 8.9 8.1 8.0 9.7 4.8 5.5 4.9 8.0 7.2 3.0 1.7 8.1 4.2 12.9 11.9 5.9 3.4 6.6 8.2 7.5 7.9 7.6 5.0 6.0 5.3 6.1 7.3 7.9 10.8 37.6 19.6 13.5 22.6 7.3 8.2 25.6 18.5 10.9 25.7 18.1 52.1 21.6 35.5 14.9 10.4 23.8 18.8 25.2 18.5 11.7 17.7 47.9 50.4 18.8 32.1 14.9 32.6 17.5 11.0 17.0 26.0 20.6 6.7 13.7 32.9 67.3 26.9 12.2 43.2 28.7 44.7 44.8 26.1 28.7 52.0 10.7 66.4 13.4 20.5 31.6 18.8 19.3 21.0 25.3 3.8 21.5 22.1 15.6 17.2 19.1 18.2 33.0 32.1 29.8 37.1 25.7 53.7 22.6 0.1 5.0 1.7 10.7 4.8 13.4 11.0 11.0 11.1 10.2 13.0 11.9 8.0 1.1 13.1 2.3 8.8 6.8 7.0 8.0 8.7 7.4 10.2 9.2 7.2 8.9 8.1 8.0 6.6 7.6 10.8 12.9 16.0 19.4 9.4 17.3 72.3 40.2 55.9 23.3 18.7 14.4 12.7 6.1 18.6 45.3 7.3 20.9 31.4 12.7 18.6 7.9 40.0 4.2 14.9 15.5 18.8 20.9 19.0 6.2 33.1 39.0 24.5 18.8 16.1 20.3 20.1 9.3 16.0 32.7 8.4 6.3 19.3 32.6 8.4 35.0 2.7 19.3 13.6 42.7 2.8 15.3 12.3 13.4 2.5 11.6 41.4 9.1 20.7 19.2 59.4 10.5 21.0 24.3 17.6 32.9 23.8 20.6 21.4 30.0 32.2 70.2 30.4 15.0 21.4 29.5 46.1 RRP15 "CGI-115, KIAA0507" ENSG00000067533 "Ribosomal RNA processing 15 homolog" Q9Y3B9 1 218285293-218337983 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024639 Approved Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome,Mitochondria" Yes No "Cluster 30: Non-specific - Translation" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli rim, Mitotic chromosome" "Nucleoplasm, Mitochondria" "HPA024639: AB_1844368" "unprognostic (2.68e-2)" "unprognostic (4.94e-2)" "unprognostic (2.04e-1)" "unprognostic (1.22e-1)" "unprognostic (5.19e-2)" "unprognostic (1.33e-2)" "prognostic unfavorable (4.26e-5)" "unprognostic (7.87e-2)" "unprognostic (1.07e-1)" "unprognostic (2.18e-1)" "unprognostic (3.65e-3)" "unprognostic (2.54e-1)" "unprognostic (2.76e-3)" "unprognostic (1.52e-1)" "unprognostic (5.77e-1)" "unprognostic (1.11e-2)" "unprognostic (3.23e-2)" 4.0 2.6 1.7 3.3 1.7 4.1 4.7 2.5 2.4 3.0 1.4 3.0 2.1 3.7 2.7 3.0 2.9 1.9 4.9 1.8 1.9 3.4 3.5 2.8 3.7 1.4 2.0 3.8 2.9 4.5 1.8 3.6 1.6 3.1 2.9 2.2 2.6 2.4 9.6 3.5 2.4 3.4 1.5 2.9 2.6 2.4 1.8 2.6 3.5 7.7 3.5 3.9 2.8 1.9 9.8 7.2 7.9 5.7 5.6 7.8 6.7 9.8 7.3 10.0 7.2 14.1 8.8 14.0 13.1 7.6 6.7 8.7 13.5 13.0 16.6 5.7 10.1 10.9 6.6 7.8 11.6 17.0 5.6 5.4 7.8 13.1 17.4 4.4 6.6 6.5 22.7 4.4 11.4 8.9 11.3 8.3 15.7 7.8 14.8 7.8 4.9 13.8 8.0 8.9 9.0 13.1 8.3 15.3 15.0 9.3 11.0 12.1 9.3 8.0 7.6 14.3 18.3 5.4 8.9 14.4 9.1 8.1 13.1 0.3 0.8 0.1 1.6 1.3 2.3 2.4 2.0 1.4 1.2 2.3 2.6 2.6 0.2 1.6 1.1 1.7 1.3 0.7 1.7 1.7 2.5 2.4 1.8 1.9 1.4 2.0 1.6 1.5 1.8 1.9 33.7 32.1 28.1 7.5 36.0 65.3 33.6 28.7 24.5 31.1 32.6 31.0 68.4 22.8 25.0 36.8 10.4 38.1 32.7 13.5 27.4 39.7 17.0 22.6 47.3 27.9 12.1 41.0 18.4 52.2 59.1 32.2 19.9 28.5 31.0 18.6 21.8 44.2 33.6 26.9 16.1 20.8 6.1 17.3 18.5 4.6 37.6 17.4 21.4 7.5 20.8 21.2 24.7 7.5 9.0 36.8 9.0 24.8 13.0 34.9 5.2 37.2 11.7 23.6 26.3 72.1 33.0 59.7 69.1 24.3 47.6 18.1 26.4 20.4 32.1 23.0 RRP1B "KIAA0179, Nnp1, PPP1R136, RRP1" ENSG00000160208 "Ribosomal RNA processing 1B" Q14684 21 43659560-43696079 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, mRNA processing, mRNA splicing, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 131.3;Early spermatids: 213.2;Late spermatids: 222.8;Rod photoreceptor cells: 143.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA017893, HPA020324" Supported Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 32: T-cells - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA017893: AB_1852274, HPA020324: AB_1852276" "unprognostic (1.03e-1)" "unprognostic (1.37e-2)" "unprognostic (4.03e-1)" "unprognostic (1.32e-3)" "unprognostic (1.24e-1)" "unprognostic (1.92e-2)" "unprognostic (2.03e-2)" "unprognostic (7.19e-2)" "unprognostic (1.98e-2)" "unprognostic (5.55e-3)" "unprognostic (1.08e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (2.95e-9)" "unprognostic (1.45e-1)" "unprognostic (1.10e-1)" "unprognostic (1.05e-2)" "unprognostic (4.24e-2)" 8.8 5.9 7.9 12.2 8.9 6.2 9.1 7.0 7.8 7.2 5.9 7.2 6.7 9.1 5.5 8.6 9.1 6.1 4.9 7.4 7.2 4.9 8.7 6.7 17.4 7.8 7.9 13.1 10.2 7.2 4.3 5.8 7.2 7.5 7.3 28.4 10.2 6.8 12.1 8.8 6.4 8.8 7.4 11.0 7.8 12.0 7.8 16.1 6.5 8.8 14.8 9.8 6.5 8.6 52.5 30.4 31.8 48.1 20.2 21.5 26.0 27.0 19.3 29.3 24.0 69.4 22.2 101.9 17.2 21.5 33.9 22.8 78.9 46.5 34.6 34.6 62.8 60.3 34.8 43.9 27.9 95.0 22.9 22.4 29.2 35.1 40.3 18.1 33.1 43.2 96.0 29.1 26.1 27.4 76.1 28.9 108.4 33.7 33.4 98.7 32.1 71.2 21.2 24.8 62.7 33.6 50.6 36.9 37.9 11.7 24.2 29.4 29.7 9.0 28.3 24.0 49.8 39.1 53.8 119.3 28.5 100.7 30.1 2.0 2.5 0.7 6.2 2.5 7.3 5.6 7.9 7.5 3.0 4.3 7.2 8.6 0.1 5.8 2.2 2.4 6.6 5.5 7.9 8.9 7.0 7.8 7.4 7.2 7.8 7.9 7.2 7.4 7.8 8.6 15.5 32.1 16.4 8.8 32.7 22.8 17.7 15.0 28.5 30.3 13.8 11.0 13.4 17.2 21.0 5.5 131.3 8.6 27.1 5.7 1.9 17.0 213.2 10.5 28.8 19.1 5.4 23.7 19.0 15.6 17.0 18.9 14.8 10.8 36.0 25.5 12.8 18.4 18.7 25.2 20.0 9.2 6.1 13.9 12.7 222.8 22.4 13.4 8.8 21.5 17.0 17.9 35.0 18.6 22.2 20.9 3.7 26.7 48.5 23.6 6.8 9.9 16.7 143.5 0.0 29.9 18.1 26.3 33.6 32.0 31.7 4.4 35.7 32.6 16.5 17.4 RRP36 "C6orf153, dJ20C7.4" ENSG00000124541 "Ribosomal RNA processing 36" Q96EU6 6 43021623-43034156 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029904, HPA029905" Uncertain Enhanced Nucleoplasm,Nucleoli Yes No "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 21: OE19 - Mitochondria" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nucleoli" "HPA029904: AB_10611817, HPA029905: AB_2673244" "unprognostic (1.76e-1)" "unprognostic (4.47e-1)" "unprognostic (3.78e-2)" "unprognostic (1.46e-2)" "unprognostic (3.25e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (5.95e-4)" "unprognostic (2.61e-1)" "unprognostic (6.83e-2)" "unprognostic (1.32e-3)" "unprognostic (1.39e-1)" "unprognostic (3.38e-1)" "prognostic unfavorable (2.48e-5)" "unprognostic (3.53e-1)" "unprognostic (1.63e-1)" "unprognostic (1.09e-1)" "unprognostic (2.09e-2)" 30.0 34.6 19.4 27.4 19.7 28.7 28.7 21.5 23.2 26.0 19.8 29.0 20.8 25.5 22.9 37.8 23.2 19.0 30.1 20.3 22.3 35.1 37.3 25.5 32.3 21.3 20.9 18.4 35.8 34.7 31.9 24.2 22.0 28.5 24.3 16.6 27.1 25.0 51.3 34.3 25.9 29.7 20.8 33.3 30.6 17.7 21.0 31.1 23.4 34.8 35.2 30.0 26.4 20.8 141.5 77.9 75.8 111.3 79.7 74.0 63.6 108.9 97.7 136.1 132.6 141.9 59.8 64.7 86.3 113.8 100.1 73.5 127.7 131.8 149.3 82.5 129.9 104.1 82.7 153.2 92.3 87.5 77.7 75.6 79.0 163.0 69.1 48.7 112.2 57.6 128.2 68.4 127.8 148.1 106.0 95.6 84.3 249.7 79.6 98.7 74.7 74.9 83.2 130.5 96.4 84.5 80.1 72.8 129.1 70.6 100.1 106.0 91.2 125.1 95.1 83.4 173.8 63.8 103.9 172.0 54.5 108.6 119.1 2.4 2.2 2.0 3.3 3.0 2.7 4.5 2.4 4.2 2.3 1.4 2.2 4.5 2.5 2.0 2.4 6.0 1.4 0.8 19.4 19.7 21.5 23.2 20.3 22.3 21.3 20.9 22.0 20.8 21.0 20.8 26.8 0.0 15.6 4.6 14.7 13.4 11.2 13.5 5.7 16.1 19.7 22.1 15.1 20.0 14.1 20.2 16.7 29.3 33.1 12.7 13.7 33.7 10.1 18.3 26.5 18.5 13.9 4.6 8.1 44.8 41.8 18.0 12.8 18.0 6.3 27.3 21.0 36.0 29.1 18.5 8.1 12.6 12.2 16.6 11.7 23.0 11.8 20.0 14.2 2.8 26.1 36.9 20.6 6.6 9.6 44.0 7.4 18.8 18.8 17.7 12.4 20.5 10.0 20.3 6.6 19.3 24.7 9.5 10.6 16.5 18.6 33.7 16.5 61.5 14.2 14.3 RSAD1 "FLJ11164, HemW" ENSG00000136444 "Radical S-adenosyl methionine domain containing 1" Q9HA92 17 50478860-50485974 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA022436, HPA022967, HPA024459" Approved Approved "Mitotic chromosome,Mitochondria" Yes NA "Cluster 39: Non-specific - mRNA processing" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 52: Non-specific - Transcription" Mitochondria "Mitotic chromosome" "HPA022436: AB_2180789, HPA022967: AB_1856484, HPA024459: " "unprognostic (8.21e-2)" "unprognostic (4.11e-3)" "unprognostic (3.72e-2)" "unprognostic (1.83e-2)" "unprognostic (3.49e-2)" "unprognostic (2.93e-2)" "unprognostic (6.01e-2)" "unprognostic (1.07e-2)" "unprognostic (2.52e-1)" "unprognostic (1.13e-2)" "prognostic favorable (5.04e-4)" "unprognostic (1.06e-1)" "unprognostic (1.65e-2)" "unprognostic (4.89e-2)" "unprognostic (2.95e-1)" "unprognostic (7.85e-2)" "unprognostic (3.22e-2)" 23.9 41.4 34.7 16.4 37.8 12.8 23.5 37.5 43.4 36.9 32.9 24.3 17.1 24.2 17.5 17.3 24.5 12.5 43.3 34.4 33.9 40.9 44.0 21.1 19.8 34.5 34.9 31.8 48.9 27.5 23.6 12.4 35.1 25.2 17.6 21.2 27.3 14.9 66.0 22.2 23.9 14.4 34.2 31.8 32.5 14.2 35.4 18.4 29.1 57.0 17.8 26.1 23.6 37.0 13.0 43.2 20.3 33.7 34.0 27.6 7.2 22.2 21.6 27.9 23.5 43.0 16.1 34.9 48.0 15.6 27.6 12.1 23.2 31.0 23.9 38.9 42.0 47.0 20.5 42.4 23.7 28.6 31.7 20.2 33.7 18.6 35.7 23.0 27.5 84.1 36.9 32.3 23.7 30.3 48.1 20.9 8.2 54.6 45.9 19.6 23.2 31.6 34.0 19.4 11.1 37.9 5.7 26.3 29.7 25.6 39.6 28.7 19.6 29.0 30.8 22.3 26.4 50.0 37.6 13.5 21.8 40.3 20.6 1.1 4.2 3.8 8.5 4.4 8.5 4.5 7.3 8.4 4.9 6.9 9.4 9.5 0.0 6.6 4.2 5.4 6.2 5.7 34.7 37.8 37.5 43.4 34.4 33.9 34.5 34.9 35.1 34.2 35.4 37.0 15.1 3.2 13.1 18.3 16.0 10.1 4.4 7.2 19.4 14.8 12.1 12.8 29.4 12.8 7.7 16.5 2.1 21.4 24.1 10.8 23.5 14.4 8.8 5.3 10.4 12.4 25.2 12.0 24.0 29.5 11.1 13.1 12.2 7.4 3.8 15.8 10.0 18.5 16.1 8.4 21.5 11.7 8.2 7.2 6.1 7.4 15.5 9.6 17.8 16.9 12.5 32.1 19.6 13.6 12.4 11.8 6.2 10.9 18.7 6.5 11.1 11.1 3.8 7.8 13.1 16.0 11.3 11.5 21.9 10.6 9.9 10.1 18.7 43.6 12.9 3.4 RSL1D1 "CSIG, DKFZP564M182, L12, PBK1, UTP30" ENSG00000171490 "Ribosomal L1 domain containing 1" O76021 16 11833850-11851580 "Predicted intracellular proteins, Ribosomal proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043483 Supported Enhanced "Nucleoli rim,Mitotic chromosome" Yes No 18000 "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" "Nucleoli rim, Mitotic chromosome" "HPA043483: AB_2678504" "unprognostic (4.46e-2)" "unprognostic (1.33e-1)" "unprognostic (2.23e-2)" "unprognostic (8.88e-2)" "unprognostic (7.77e-2)" "prognostic unfavorable (2.95e-4)" "prognostic unfavorable (1.38e-4)" "unprognostic (6.66e-2)" "unprognostic (1.73e-1)" "unprognostic (2.28e-1)" "unprognostic (2.24e-3)" "unprognostic (1.24e-1)" "prognostic unfavorable (3.24e-4)" "unprognostic (4.72e-2)" "unprognostic (1.36e-1)" "unprognostic (2.02e-2)" "unprognostic (2.68e-2)" 39.3 32.2 11.1 36.9 11.7 46.7 78.8 13.4 14.1 47.6 12.2 35.7 32.6 44.0 28.8 38.2 44.5 30.5 33.7 11.9 12.5 33.0 39.1 26.4 48.2 11.6 11.4 118.5 43.6 28.8 13.2 30.0 12.2 33.3 37.9 15.1 42.0 34.0 87.3 34.1 29.2 36.6 13.3 26.9 25.1 22.4 13.3 41.8 34.8 51.7 65.1 48.0 26.4 15.4 90.7 84.3 69.1 87.1 88.6 157.9 81.9 82.1 91.4 104.0 105.9 82.6 83.1 225.6 133.1 68.6 72.1 62.5 186.7 124.4 168.4 88.8 100.7 111.6 75.9 188.0 165.4 159.5 71.3 116.6 173.2 107.6 248.2 77.8 102.4 87.0 198.6 101.5 129.3 100.8 125.7 92.6 177.7 108.1 86.1 129.2 127.3 240.1 92.9 78.0 96.4 79.2 155.0 116.6 110.0 70.9 100.5 122.2 63.2 69.0 77.3 66.0 120.0 81.3 126.2 261.7 75.0 164.9 94.1 14.1 123.2 12.6 69.7 119.1 129.6 132.6 129.5 91.7 130.8 117.3 185.4 136.8 7.1 124.6 120.7 80.2 100.9 253.0 11.1 11.7 13.4 14.1 11.9 12.5 11.6 11.4 12.2 13.3 13.3 15.4 111.2 141.1 156.6 5.5 198.1 330.9 338.6 251.0 299.3 39.9 241.1 344.4 188.4 74.4 198.1 49.7 22.9 186.4 118.7 41.2 135.0 134.5 22.8 76.0 181.1 118.1 94.5 104.5 11.0 186.2 286.8 180.9 88.2 100.0 152.6 106.6 64.2 78.5 147.6 38.7 11.6 126.4 107.8 153.0 177.3 18.5 199.4 141.0 92.5 3.7 276.5 52.8 113.3 3.5 7.3 135.4 75.1 126.0 104.6 226.5 110.5 155.0 81.3 30.8 59.2 245.4 151.5 111.2 136.0 203.5 290.2 160.6 166.5 162.8 184.3 225.1 RTN4RL1 "DKFZp547J144, NgR3, NGRH2" ENSG00000185924 "Reticulon 4 receptor like 1" Q86UN2 17 1934677-2025334 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 20.6;Cone photoreceptor cells: 37.5;Excitatory neurons: 43.5;Horizontal cells: 33.7;Inhibitory neurons: 18.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "hippocampal formation: 12.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 10.9;HaCaT: 10.8;hTCEpi: 10.1;T-47d: 13.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044428 Uncertain Approved "Nucleoplasm,Plasma membrane,Actin filaments,Midbody" "Intracellular and membrane" Yes NA 35000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Actin filaments" "Nucleoplasm, Plasma membrane, Midbody" "HPA044428: AB_10963229" "unprognostic (5.23e-1)" "unprognostic (3.52e-2)" "unprognostic (2.06e-1)" "unprognostic (2.12e-1)" "unprognostic (2.93e-2)" "unprognostic (7.25e-2)" "unprognostic (2.61e-3)" "unprognostic (1.17e-1)" "unprognostic (8.97e-3)" "unprognostic (6.21e-2)" "unprognostic (2.55e-3)" "unprognostic (6.32e-3)" "prognostic unfavorable (7.69e-4)" "unprognostic (3.86e-2)" "unprognostic (1.05e-1)" "unprognostic (7.01e-2)" "unprognostic (3.15e-2)" 4.0 3.1 4.6 0.3 4.0 0.0 6.4 0.0 9.2 2.1 0.0 0.4 0.1 0.8 0.2 1.3 1.5 0.6 2.3 12.3 0.3 1.6 2.6 1.6 0.1 0.0 0.5 0.9 1.8 1.3 5.9 0.3 0.0 3.4 0.1 8.5 4.4 2.0 1.8 9.6 0.5 0.3 0.0 1.1 0.7 0.8 1.9 0.2 1.4 0.4 0.1 1.5 2.2 0.0 1.4 1.6 1.8 2.5 2.0 0.3 0.0 0.1 1.1 0.3 0.0 0.0 0.0 0.0 0.1 10.9 0.2 10.8 4.6 0.1 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 10.1 0.0 3.6 0.0 0.0 2.5 0.1 0.0 0.1 0.5 0.0 0.0 0.3 0.0 0.3 0.8 0.3 1.2 0.0 0.0 2.2 0.0 0.3 0.8 1.7 0.2 13.3 0.1 0.0 0.0 0.2 0.5 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 4.0 0.0 9.2 12.3 0.3 0.0 0.5 0.0 0.0 1.9 0.0 1.0 0.0 2.2 1.6 0.1 2.7 0.2 0.0 1.8 20.6 5.4 4.3 3.0 1.5 1.3 3.7 37.5 0.0 0.1 0.0 0.0 0.6 0.3 0.0 0.0 0.7 0.0 0.0 43.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 6.1 3.3 1.8 33.7 18.6 0.0 0.0 0.3 0.4 1.1 0.0 0.1 3.6 7.5 0.0 1.8 0.0 8.5 1.7 0.1 0.0 0.0 0.1 0.9 0.0 0.1 1.5 10.0 0.0 0.0 0.6 0.0 0.2 0.5 2.8 0.0 0.2 0.0 0.0 0.3 S100A10 "42C, ANX2LG, CAL1L, CLP11, P11" ENSG00000197747 "S100 calcium binding protein A10" P60903 1 151982915-151993859 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1760.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 3820.4;Langerhans cells: 3945.6;Pancreatic endocrine cells: 4570.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 2005.4;monocytes: 1235.2;T-cells: 1180.0" "Cell line enhanced" "Detected in all" "OE19: 4936.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003340, CAB025484" Enhanced Approved Mitochondria Yes No 270000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" Mitochondria "CAB025484: , HPA003340: AB_1856531" "unprognostic (2.13e-1)" "unprognostic (1.51e-3)" "unprognostic (1.01e-1)" "unprognostic (3.15e-1)" "unprognostic (6.20e-2)" "prognostic unfavorable (3.33e-4)" "prognostic unfavorable (1.00e-4)" "prognostic unfavorable (2.66e-5)" "unprognostic (1.09e-2)" "unprognostic (9.48e-2)" "prognostic unfavorable (3.88e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (3.80e-8)" "unprognostic (1.09e-1)" "unprognostic (1.50e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (3.84e-4)" 775.1 376.9 71.1 244.8 76.6 133.7 519.6 75.5 139.8 478.0 78.5 867.3 461.4 110.1 56.7 1760.5 188.7 212.4 340.9 72.4 132.8 735.0 157.7 689.8 133.3 148.2 105.0 234.0 145.0 36.3 71.0 326.9 108.5 164.9 924.2 51.3 422.8 105.0 106.0 483.4 448.0 288.2 98.2 111.2 189.1 145.8 138.8 118.3 143.5 145.4 289.8 338.4 803.1 110.3 1251.3 1085.9 3.4 241.6 1351.4 1711.3 972.5 730.1 912.1 613.8 606.5 1975.4 1671.4 2.3 689.1 1208.0 661.7 2227.5 337.0 2786.6 495.3 242.5 127.1 163.8 461.5 468.1 507.0 60.2 126.7 470.8 2195.5 660.6 738.6 487.6 1326.0 78.9 2.9 3.6 753.8 940.0 11.0 376.5 163.6 4936.7 1671.4 1.6 242.4 27.1 2348.3 317.0 11.1 9.5 1259.2 374.3 539.8 1213.0 882.2 130.5 1654.9 285.5 737.2 1362.3 459.2 34.4 7.8 225.2 1709.5 51.7 977.8 359.5 1235.2 299.7 425.7 758.7 443.3 232.4 652.3 539.0 2005.4 140.1 237.7 363.1 43.6 355.0 664.7 329.6 1180.0 1313.4 71.1 76.6 75.5 139.8 72.4 132.8 148.2 105.0 108.5 98.2 138.8 110.3 1197.3 2554.5 537.7 3.9 244.0 1594.8 1171.4 2183.2 795.6 11.6 241.1 281.4 111.2 693.4 994.6 950.9 4.2 1271.5 476.2 3820.4 1524.1 1811.7 314.2 901.0 104.6 1061.2 1078.1 114.2 0.4 2105.0 527.4 1751.3 432.8 1270.7 289.5 840.0 864.5 206.9 1023.1 16.8 0.9 1723.1 272.6 795.2 3945.6 274.2 647.1 1338.1 1632.8 28.1 1544.2 24.8 285.3 4.0 0.6 4570.5 3391.8 64.7 244.5 2782.5 2146.1 495.6 620.3 32.5 144.7 801.6 529.5 30.4 115.9 1940.1 1242.0 375.8 801.0 38.5 1998.0 2290.6 S100A5 S100D ENSG00000196420 "S100 calcium binding protein A5" P33763 1 153537147-153541765 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 3.6;thyroid gland: 5.2" "Cell type enhanced" "Detected in some" "Collecting duct cells: 3.7;Distal tubular cells: 3.9;Extravillous trophoblasts: 8.5;Langerhans cells: 3.1;Theca cells: 6.8" "Cancer enhanced" "Detected in many" "thyroid cancer: 11.7" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 3.0;granulocytes: 1.4;T-cells: 4.6" "Cell line enhanced" "Detected in many" "OE19: 34.3;RPTEC TERT1: 11.9;RT4: 19.9;SCLC-21H: 17.3" "Region enriched" "Detected in many" 86 "olfactory bulb: 980.0" "Region enriched" "Detected in single" 15 "olfactory bulb: 5.6" HPA064184 Approved Nucleoplasm Yes NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA064184: AB_2685206" "unprognostic (6.09e-2)" "unprognostic (2.92e-2)" "unprognostic (8.92e-2)" "unprognostic (1.63e-5)" "unprognostic (2.43e-3)" "unprognostic (2.45e-2)" "unprognostic (1.52e-3)" "unprognostic (4.11e-2)" "unprognostic (2.69e-1)" "unprognostic (7.39e-3)" "unprognostic (3.08e-2)" "unprognostic (2.20e-2)" "unprognostic (1.07e-2)" "unprognostic (9.53e-2)" "unprognostic (5.70e-2)" "unprognostic (4.68e-3)" 0.2 0.1 0.3 0.1 0.3 0.7 0.2 0.9 0.8 0.3 0.1 0.2 1.5 0.6 0.1 0.9 0.5 1.0 0.1 0.3 0.4 2.9 0.0 0.5 1.5 0.4 0.3 0.1 0.0 0.0 0.1 0.0 0.5 0.3 0.0 0.0 0.2 0.0 0.1 3.6 0.3 0.0 0.3 0.4 1.2 0.1 0.4 0.7 5.2 0.1 0.4 1.1 0.3 0.4 2.2 5.7 0.0 0.0 0.6 0.4 0.4 1.0 1.3 0.7 1.4 0.6 4.2 0.0 3.7 2.1 0.4 1.7 0.1 1.0 0.9 0.5 0.0 2.7 2.6 0.2 0.4 0.0 3.5 0.0 1.1 2.7 0.8 0.5 0.5 0.0 0.7 0.2 3.0 0.2 0.5 1.3 0.2 34.3 9.7 0.0 1.8 1.1 11.9 19.9 17.3 0.0 0.2 9.0 0.8 1.5 0.0 0.5 0.4 0.1 1.3 2.6 1.7 0.0 0.9 0.0 0.5 0.7 0.4 0.0 0.7 1.4 1.2 0.1 4.6 0.5 2.6 1.3 1.8 0.3 1.4 0.6 1.2 0.0 0.4 3.0 3.9 0.7 0.3 0.3 0.9 0.8 0.3 0.4 0.4 0.3 0.5 0.3 0.4 0.4 0.0 0.0 0.0 0.0 0.1 0.6 0.2 0.4 0.0 0.0 0.3 0.1 0.0 0.0 0.2 3.7 0.0 0.1 0.2 0.1 3.9 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 8.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 2.0 0.6 3.1 0.0 0.3 0.5 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.2 1.2 0.0 0.0 0.1 0.2 0.0 0.6 0.0 0.0 0.2 0.2 0.0 0.0 0.0 1.0 0.3 0.6 6.8 0.3 0.6 SAFB "HET, SAFB1" ENSG00000160633 "Scaffold attachment factor B" Q15424 19 5623035-5668478 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001969, HPA016832, HPA020076" Supported Enhanced Nucleoplasm,Midbody Yes NA 67000 "Cluster 14: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Midbody "CAB001969: , HPA016832: AB_1850622, HPA020076: AB_1850624" "unprognostic (2.41e-2)" "unprognostic (8.18e-3)" "unprognostic (6.66e-2)" "unprognostic (3.81e-3)" "unprognostic (6.50e-2)" "unprognostic (7.82e-2)" "unprognostic (1.62e-3)" "unprognostic (9.31e-2)" "unprognostic (5.76e-2)" "unprognostic (4.85e-2)" "prognostic favorable (9.75e-5)" "unprognostic (3.25e-2)" "unprognostic (3.53e-3)" "unprognostic (3.14e-2)" "unprognostic (2.67e-2)" "unprognostic (4.07e-1)" "prognostic favorable (1.70e-4)" 43.4 40.1 27.9 34.5 31.6 55.6 44.2 37.1 33.8 52.5 24.0 50.4 28.8 49.7 14.0 45.2 45.2 17.3 46.0 27.6 31.4 39.3 42.6 45.8 39.0 32.0 29.2 54.4 44.3 22.7 43.4 27.7 31.0 46.4 17.7 32.1 42.8 19.6 85.3 60.9 48.4 20.6 23.9 58.9 43.2 43.4 32.4 43.4 42.6 30.2 29.4 43.4 47.6 44.6 94.1 81.8 95.3 62.0 41.6 36.4 111.5 68.0 43.7 56.8 47.4 124.2 52.0 149.7 52.9 33.8 48.3 86.4 92.7 55.7 58.1 101.6 94.6 109.9 75.1 118.0 39.4 136.7 93.6 33.6 50.9 50.8 53.2 40.4 45.5 65.9 156.7 75.0 43.5 84.7 146.2 109.9 128.3 63.7 81.1 144.4 105.1 104.8 44.4 76.6 88.2 76.4 76.3 61.2 76.2 54.3 56.3 74.4 71.4 57.6 71.6 72.2 106.2 121.5 112.0 133.3 55.4 112.6 77.7 65.4 47.4 84.1 55.9 47.8 57.1 53.1 55.1 54.9 53.2 47.6 56.8 55.1 53.1 54.6 79.8 44.6 58.6 55.4 27.9 31.6 37.1 33.8 27.6 31.4 32.0 29.2 31.0 23.9 32.4 44.6 34.8 32.1 21.0 33.3 59.1 65.6 50.2 41.0 51.2 41.3 28.9 30.2 43.4 17.2 47.6 16.5 35.5 53.6 47.7 41.0 25.4 44.0 10.0 56.6 55.6 38.9 29.8 29.6 28.6 35.0 55.2 42.6 33.1 46.4 50.6 52.6 23.2 28.1 38.0 50.5 29.8 43.4 32.6 23.0 52.6 8.2 35.8 37.0 30.2 30.9 55.6 30.0 50.4 34.2 41.5 32.3 29.9 25.9 50.9 44.8 33.7 28.1 72.9 47.2 19.7 44.5 45.1 89.7 94.3 37.2 65.4 62.5 52.2 44.0 40.5 38.9 SALL4 "dJ1112F19.1, ZNF797" ENSG00000101115 "Spalt like transcription factor 4" Q9UJQ4 20 51782331-51802521 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 3.9;thyroid gland: 5.8" "Cell type enriched" "Detected in some" 4 "Horizontal cells: 26.9" "Cancer enriched" "Detected in many" 11 "testis cancer: 22.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 9 "NK-cell: 2.5" "Lineage enriched" "Detected in single" 9 "NK-cells: 2.5" "Cell line enhanced" "Detected in some" "AF22: 25.0;AN3-CA: 17.5;BEWO: 33.2;NTERA-2: 60.2;SiHa: 15.6;SuSa: 39.7" "Not detected" "Not detected" "HPA015291, HPA015791" Enhanced Enhanced Nucleoplasm Yes No "Cluster 15: NK-cells - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA015291: AB_1856548, HPA015791: AB_1856547" "unprognostic (1.30e-1)" "unprognostic (2.35e-2)" "unprognostic (1.11e-1)" "unprognostic (1.09e-3)" "unprognostic (3.55e-2)" "unprognostic (7.43e-2)" "unprognostic (3.63e-2)" "unprognostic (1.47e-1)" "unprognostic (1.20e-1)" "unprognostic (9.23e-2)" "unprognostic (2.50e-2)" "unprognostic (2.39e-2)" "unprognostic (2.42e-8)" "unprognostic (5.90e-3)" "unprognostic (1.82e-1)" "unprognostic (5.00e-5)" "unprognostic (7.41e-2)" 0.2 0.3 0.2 0.2 0.2 0.8 0.2 0.4 0.2 0.2 0.3 0.2 0.1 0.2 0.4 0.2 0.2 0.0 0.1 0.2 0.4 0.8 1.6 0.2 0.1 0.2 0.3 0.1 2.1 2.0 0.5 0.2 0.2 2.4 0.2 0.5 0.9 0.2 0.1 0.2 0.4 0.1 0.2 0.5 0.2 3.9 0.3 0.0 5.8 0.0 0.1 0.4 0.1 0.4 0.0 1.7 25.0 17.5 0.0 0.1 33.2 0.0 0.2 0.1 0.3 9.0 0.2 0.0 0.3 0.3 0.3 4.3 0.2 0.1 0.3 0.4 0.0 0.0 7.0 0.4 0.1 0.0 1.9 0.7 0.5 0.1 0.1 0.0 0.4 0.0 0.0 0.1 0.0 1.8 0.0 0.1 60.2 0.2 0.4 2.3 0.0 0.0 0.0 0.5 5.7 3.1 15.6 0.1 1.5 39.7 0.1 1.0 0.0 0.9 3.3 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.5 0.0 0.0 0.0 0.0 0.2 0.2 0.4 0.2 0.2 0.4 0.2 0.3 0.2 0.2 0.3 0.4 0.1 0.0 2.0 1.6 0.0 0.0 1.1 0.1 0.0 0.4 0.3 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 3.6 0.0 0.2 0.1 0.2 1.2 0.0 4.1 0.2 0.0 0.4 0.0 0.4 0.0 0.2 0.0 0.6 0.2 26.9 3.5 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 4.7 0.0 0.2 1.0 2.0 2.0 0.2 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.4 0.0 0.2 0.2 0.7 5.5 0.0 0.0 0.0 0.0 0.1 0.0 1.2 SDC3 "N-syndecan, SYND3" ENSG00000162512 "Syndecan 3" O75056 1 30869466-30908758 "Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 140.3" "Cell type enhanced" "Detected in many" "Astrocytes: 64.6;Endometrial stromal cells: 59.8;Kupffer cells: 174.8;Late spermatids: 82.4;Oligodendrocyte precursor cells: 108.6" "Group enriched" "Detected in all" 5 "glioma: 115.2;melanoma: 102.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SK-MEL-30: 249.5;WM-115: 342.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017087, CAB025786, HPA048085" Approved Approved Nucleoplasm,Mitochondria Yes No "Cluster 42: Non-specific - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria Nucleoplasm "CAB025786: , HPA017087: AB_1857706, HPA048085: AB_2680256" "unprognostic (1.42e-3)" "unprognostic (5.52e-2)" "unprognostic (1.20e-1)" "unprognostic (4.55e-2)" "unprognostic (1.79e-2)" "unprognostic (1.87e-1)" "unprognostic (1.79e-3)" "unprognostic (2.83e-1)" "prognostic favorable (2.36e-4)" "unprognostic (9.77e-2)" "unprognostic (5.14e-2)" "unprognostic (1.65e-2)" "prognostic unfavorable (1.71e-4)" "unprognostic (6.45e-2)" "unprognostic (2.74e-1)" "unprognostic (9.80e-3)" "unprognostic (1.46e-1)" 33.9 99.1 103.9 22.9 123.9 3.0 17.9 97.0 105.4 36.5 38.1 57.3 12.3 62.3 12.3 17.6 29.8 30.0 22.7 91.6 111.1 10.4 22.3 22.5 36.4 140.3 121.2 9.3 7.5 13.2 11.8 18.1 107.9 26.9 14.6 27.2 15.9 52.7 27.1 10.1 16.5 66.2 112.4 91.0 19.7 3.3 124.4 6.4 9.8 9.1 7.6 32.7 13.4 91.9 12.9 10.4 80.4 36.5 60.6 14.8 13.8 31.4 48.0 15.0 9.5 2.0 12.3 0.9 68.6 95.3 21.8 16.3 8.7 7.6 10.0 5.7 6.3 0.0 4.1 1.8 56.9 0.3 8.2 35.4 35.9 1.0 15.4 86.6 20.1 3.6 6.2 0.5 30.6 15.0 0.3 0.2 36.4 10.2 9.4 0.8 75.2 2.8 19.7 14.9 28.9 17.5 40.3 5.7 249.5 50.8 5.7 6.1 19.3 18.6 28.2 2.0 7.5 0.1 0.5 0.9 1.9 0.2 342.9 1.1 0.3 0.2 0.1 0.6 0.2 0.1 0.1 0.2 0.2 0.2 0.2 0.2 0.5 0.4 0.4 0.2 0.2 0.2 103.9 123.9 97.0 105.4 91.6 111.1 140.3 121.2 107.9 112.4 124.4 91.9 37.3 0.0 2.2 64.6 0.5 2.5 3.4 4.7 4.0 9.6 14.9 25.5 4.9 14.3 2.6 47.8 0.0 2.1 0.2 0.8 0.0 10.7 17.7 14.1 59.8 17.9 3.0 0.0 14.7 3.1 3.4 16.6 3.1 28.6 0.0 17.5 20.3 1.0 14.3 0.0 13.9 1.1 6.1 174.8 3.1 82.4 2.1 24.4 19.6 18.7 4.0 2.5 1.0 108.6 6.8 6.0 1.3 7.9 1.5 8.5 0.0 0.6 0.4 27.8 0.0 1.1 9.1 0.7 0.4 1.3 2.3 3.6 2.3 15.4 1.6 5.7 SELENOO SELO ENSG00000073169 "Selenoprotein O" Q9BVL4 22 50200979-50217616 "Enzymes, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 27.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 21.1;Granulosa cells: 34.7;Proximal tubular cells: 41.7;Theca cells: 29.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071795, HPA079100" Approved Supported "Mitotic chromosome,Mitochondria" "Intracellular and membrane" Yes NA "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "Mitotic chromosome" "HPA071795: , HPA079100: " "unprognostic (1.79e-1)" "unprognostic (2.07e-3)" "unprognostic (1.60e-1)" "unprognostic (2.50e-3)" "unprognostic (3.89e-1)" "unprognostic (2.33e-2)" "unprognostic (2.85e-2)" "unprognostic (5.91e-2)" "unprognostic (1.51e-1)" "unprognostic (5.62e-2)" "unprognostic (8.20e-3)" "unprognostic (8.91e-2)" "unprognostic (1.81e-2)" "unprognostic (7.31e-2)" "unprognostic (1.98e-1)" "unprognostic (2.52e-1)" "prognostic favorable (8.32e-4)" 6.7 6.7 2.3 4.5 3.4 13.9 4.8 11.7 6.8 5.6 2.5 5.3 8.0 5.9 2.8 8.2 5.7 4.1 5.3 3.0 1.1 6.6 27.9 4.7 6.4 4.6 2.7 5.0 13.1 3.0 4.1 3.0 3.7 5.6 2.0 2.9 7.7 4.1 12.3 8.2 6.5 2.4 2.3 6.5 7.0 3.7 3.1 4.4 5.1 4.1 3.9 5.1 6.1 6.0 12.0 7.7 4.2 4.7 5.6 4.1 8.6 11.8 5.6 7.0 5.5 10.6 7.5 7.9 9.2 4.7 3.9 26.2 6.5 10.7 1.4 2.3 29.9 5.7 17.4 6.4 2.8 10.6 6.9 5.4 7.2 4.5 3.5 4.5 5.8 5.3 7.8 5.6 2.9 18.6 5.7 16.4 3.7 2.8 15.6 17.6 5.9 11.8 4.3 15.3 8.4 9.3 12.8 11.3 7.5 2.1 8.7 7.5 9.5 6.0 8.3 6.5 7.1 13.8 3.6 4.7 6.8 6.9 3.5 0.0 1.1 1.3 0.2 0.4 0.5 0.0 0.2 0.5 1.1 0.2 0.1 0.4 0.5 0.0 0.4 0.4 0.2 0.3 2.3 3.4 11.7 6.8 3.0 1.1 4.6 2.7 3.7 2.3 3.1 6.0 11.8 0.0 21.1 0.0 4.1 0.0 0.0 0.0 0.0 0.0 13.3 13.2 0.0 0.0 5.6 9.2 0.0 3.1 12.2 0.0 15.6 3.6 0.0 11.8 10.9 3.0 0.0 0.0 0.0 4.6 2.4 6.0 0.0 15.2 3.8 34.7 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 2.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 4.5 0.0 0.0 41.7 3.6 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 1.9 5.5 29.6 0.0 0.0 SENP3 "DKFZP586K0919, DKFZp762A152, SMT3IP1, SSP3, Ulp1" ENSG00000161956 "SUMO specific peptidase 3" Q9H4L4 17 7561919-7571969 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 22.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" HPA060290 Supported Supported Nucleoplasm,Nucleoli Yes No "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nucleoli" "HPA060290: AB_2684244" "unprognostic (5.68e-2)" "unprognostic (2.39e-1)" "unprognostic (1.65e-1)" "unprognostic (1.01e-1)" "unprognostic (3.34e-1)" "unprognostic (3.48e-1)" "unprognostic (1.30e-3)" "unprognostic (2.82e-1)" "unprognostic (7.37e-2)" "unprognostic (3.72e-2)" "prognostic favorable (6.22e-5)" "unprognostic (2.71e-2)" "unprognostic (1.96e-1)" "unprognostic (1.42e-1)" "unprognostic (1.37e-1)" "unprognostic (8.21e-2)" "unprognostic (2.56e-2)" 24.2 24.0 43.7 21.0 42.6 25.4 23.7 38.5 47.9 23.7 38.5 32.4 21.2 26.7 27.4 25.4 25.9 19.3 25.2 42.6 39.8 34.1 20.5 28.6 26.5 40.4 42.2 26.8 26.4 38.1 26.4 22.5 41.1 23.0 25.4 24.7 24.8 26.0 33.5 28.6 25.2 28.9 39.5 28.3 27.0 29.0 44.0 33.8 23.9 30.9 31.2 29.7 21.8 42.0 76.4 90.8 52.7 82.5 58.6 42.8 54.8 54.8 56.0 93.4 87.2 54.9 32.5 90.3 52.6 72.7 62.3 72.0 114.4 85.8 78.0 63.7 105.0 46.7 74.8 56.9 79.1 44.0 57.9 55.1 86.5 107.1 103.5 53.3 76.0 102.1 61.5 24.7 73.0 51.4 107.9 33.6 64.2 70.9 54.5 97.1 48.8 52.4 62.9 44.0 52.5 67.6 55.3 52.7 60.0 66.6 44.1 28.5 40.5 53.0 45.9 51.3 119.0 36.3 40.4 57.3 53.9 45.7 80.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 43.7 42.6 38.5 47.9 42.6 39.8 40.4 42.2 41.1 39.5 44.0 42.0 4.5 3.2 5.4 0.0 4.9 8.5 6.4 1.6 10.2 6.1 6.7 11.0 7.1 7.2 3.6 1.8 22.9 3.0 4.8 2.6 0.0 2.3 1.4 4.0 4.2 4.7 6.6 1.3 0.0 2.4 2.3 3.8 3.6 4.7 1.3 5.2 8.2 2.7 1.5 6.7 0.0 3.0 2.0 6.0 6.4 0.7 4.1 4.9 3.6 0.0 4.7 5.5 4.1 0.0 0.0 2.1 0.8 2.2 6.4 6.1 4.0 1.1 2.1 7.3 0.0 5.2 4.4 3.7 4.0 7.4 11.6 4.1 4.9 3.0 3.7 6.4 SEPTIN2 "DIFF6, hNedd5, KIAA0158, NEDD5, Pnutl3, SEPT2" ENSG00000168385 "Septin 2" Q15019 2 241315100-241354027 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Spermatogenesis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 89.9;Cardiomyocytes: 133.5;Cytotrophoblasts: 135.9;Extravillous trophoblasts: 190.1;Hofbauer cells: 136.8;Syncytiotrophoblasts: 139.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017190, HPA018481" Supported Enhanced "Nucleoplasm,Plasma membrane,Actin filaments,Cytokinetic bridge" Yes No 3300000 "Cluster 27: Non-specific - Gene expression" "Cluster 57: Non-specific - Angiogenesis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 24: Non-specific - Transcription regulation" "Actin filaments" "Nucleoplasm, Plasma membrane, Cytokinetic bridge" "CAB017190: , HPA018481: AB_1856684" "unprognostic (6.31e-2)" "unprognostic (5.27e-2)" "unprognostic (2.95e-2)" "unprognostic (4.03e-2)" "prognostic favorable (8.21e-4)" "unprognostic (3.32e-1)" "prognostic unfavorable (3.66e-4)" "unprognostic (1.96e-3)" "unprognostic (1.83e-2)" "unprognostic (5.69e-2)" "unprognostic (1.11e-3)" "unprognostic (3.16e-1)" "unprognostic (9.58e-3)" "unprognostic (8.11e-2)" "unprognostic (9.53e-2)" "unprognostic (1.40e-1)" "unprognostic (2.17e-2)" 246.0 155.0 192.8 159.7 216.1 125.3 177.2 208.8 220.6 233.8 183.2 179.7 140.8 209.0 176.7 161.1 168.7 193.8 211.8 180.5 209.6 212.6 117.1 184.5 157.2 227.2 203.3 221.7 214.2 220.1 112.7 217.3 232.2 186.1 188.6 114.0 163.3 218.2 160.6 119.0 154.8 253.1 224.1 164.9 152.6 145.0 198.3 141.8 224.6 163.5 180.5 221.0 116.7 245.3 245.1 207.7 561.7 370.8 511.5 555.0 289.1 517.3 508.9 329.1 417.2 118.7 258.4 96.1 119.4 599.0 176.7 209.6 377.7 347.9 535.5 241.9 262.2 388.9 200.5 444.5 311.6 374.4 228.0 495.1 224.8 275.0 259.1 369.8 576.2 240.9 357.4 138.0 491.9 171.5 226.7 227.3 412.5 215.2 152.8 216.2 707.4 204.7 483.5 359.9 401.4 270.0 363.0 245.7 353.0 397.9 146.9 333.4 555.5 399.2 166.2 392.9 320.6 267.7 251.9 340.9 344.7 225.1 571.6 172.0 165.0 98.3 101.0 184.1 125.1 87.4 97.9 104.2 183.8 77.2 84.4 89.6 58.9 191.4 144.8 138.7 108.0 241.2 192.8 216.1 208.8 220.6 180.5 209.6 227.2 203.3 232.2 224.1 198.3 245.3 89.9 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 133.5 0.0 0.0 0.0 0.0 135.9 39.9 0.0 0.0 0.0 0.0 0.0 0.0 25.3 0.0 0.0 0.0 0.0 190.1 50.4 0.0 0.0 0.0 0.0 0.0 0.0 136.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.7 0.0 0.0 0.0 0.0 139.0 6.5 0.0 0.0 0.0 SEPTIN7 "CDC10, CDC3, SEPT7, SEPT7A" ENSG00000122545 "Septin 7" Q16181 7 35800932-35907105 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 570.9" "Group enriched" "Detected in some" 4 "Adipocytes: 192.1;Cardiomyocytes: 227.0;Cytotrophoblasts: 171.4;dendritic cells: 196.6;Extravillous trophoblasts: 198.2;Fibroblasts: 153.5;Hofbauer cells: 191.0;Smooth muscle cells: 190.0;Syncytiotrophoblasts: 124.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023309, HPA029524" Enhanced Approved "Nucleoli,Plasma membrane,Actin filaments,Midbody,Cytosol" Yes No 4300000 "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" "Actin filaments" "Nucleoli, Plasma membrane, Midbody, Cytosol" "HPA023309: AB_10600093, HPA029524: AB_10601573" "unprognostic (7.91e-3)" "unprognostic (6.89e-3)" "unprognostic (9.49e-2)" "unprognostic (1.27e-1)" "unprognostic (1.04e-1)" "unprognostic (2.22e-2)" "prognostic unfavorable (2.37e-4)" "unprognostic (2.00e-2)" "unprognostic (4.43e-2)" "unprognostic (7.13e-2)" "unprognostic (3.56e-2)" "unprognostic (7.66e-2)" "prognostic unfavorable (2.78e-4)" "unprognostic (2.86e-2)" "unprognostic (1.74e-1)" "unprognostic (1.71e-1)" "unprognostic (2.43e-3)" 127.1 95.1 352.6 98.8 386.1 131.0 99.5 334.3 570.9 111.5 289.5 116.4 55.7 126.5 121.5 106.6 84.1 117.5 172.1 344.1 341.6 82.9 76.9 98.6 150.9 337.4 355.9 138.2 37.0 81.1 62.6 143.5 339.1 93.9 94.8 119.5 50.3 95.5 82.9 105.0 74.9 145.2 345.1 108.3 59.4 70.3 367.7 159.0 78.2 104.3 149.7 125.0 86.9 411.9 198.1 94.3 232.0 153.2 256.7 263.1 119.3 248.6 228.6 206.7 177.0 147.7 148.9 186.2 164.2 254.9 274.9 146.3 166.3 166.4 294.0 127.8 88.4 149.8 123.4 80.8 149.4 182.7 157.7 171.7 127.1 163.8 159.4 215.6 221.0 143.3 120.1 141.9 341.6 92.8 185.6 304.3 249.7 183.1 132.6 188.3 220.9 107.6 202.6 146.1 124.3 217.4 173.5 220.1 151.8 377.1 163.1 198.7 187.3 207.2 246.7 129.9 278.5 165.9 163.4 470.2 132.4 301.2 449.3 266.8 86.0 150.1 214.8 100.1 220.7 165.6 151.5 199.6 100.8 155.5 134.4 171.2 160.9 298.7 110.5 71.0 147.4 241.7 352.6 386.1 334.3 570.9 344.1 341.6 337.4 355.9 339.1 345.1 367.7 411.9 192.1 0.0 0.0 0.0 41.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 227.0 0.0 0.0 0.0 0.0 171.4 196.6 0.0 0.0 0.0 0.0 0.0 0.0 40.1 0.0 0.0 0.0 0.0 198.2 153.5 0.0 0.0 0.0 0.0 0.0 0.0 191.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 190.0 0.0 0.0 0.0 0.0 124.2 30.4 0.0 0.0 0.0 SETD7 "KIAA1717, KMT7, SET7, SET7/9, Set9" ENSG00000145391 "SET domain containing 7, histone lysine methyltransferase" Q8WTS6 4 139495941-139606699 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058111 Enhanced Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA058111: AB_2683607" "prognostic unfavorable (8.28e-4)" "unprognostic (7.07e-2)" "unprognostic (4.04e-1)" "unprognostic (2.07e-1)" "unprognostic (2.92e-1)" "unprognostic (4.82e-2)" "unprognostic (1.48e-2)" "unprognostic (2.04e-1)" "unprognostic (1.71e-2)" "unprognostic (9.10e-2)" "unprognostic (6.44e-2)" "unprognostic (7.75e-2)" "unprognostic (1.37e-1)" "unprognostic (6.16e-3)" "unprognostic (1.17e-1)" "unprognostic (6.92e-2)" "unprognostic (6.56e-3)" 44.7 18.5 17.8 15.1 17.7 9.7 27.3 19.3 17.3 40.5 21.2 23.5 7.3 33.0 12.6 28.1 18.8 26.7 41.0 16.6 19.4 10.1 50.1 19.2 11.7 25.0 20.3 19.6 21.9 34.7 8.8 19.1 24.7 35.1 15.3 11.5 16.2 20.6 106.6 22.7 12.1 34.8 24.6 17.0 20.1 14.4 24.5 10.1 14.1 73.7 15.9 23.4 18.2 29.2 28.4 37.2 13.0 7.8 77.1 65.9 29.6 65.7 67.3 32.4 27.1 22.7 37.2 68.0 25.5 110.5 22.4 13.9 44.3 51.3 52.4 32.8 33.0 8.9 45.5 0.8 38.4 31.9 12.9 57.7 58.6 52.1 54.6 41.2 41.7 27.8 5.5 96.1 42.3 46.8 21.0 4.6 6.4 40.8 23.9 19.7 48.4 37.3 31.5 25.3 55.3 18.5 44.7 63.5 15.3 12.6 25.3 28.0 68.8 57.1 40.7 68.6 55.2 89.6 86.8 42.2 65.9 31.1 28.0 0.5 3.9 0.2 0.3 2.0 2.7 1.0 1.1 1.1 4.4 1.2 0.4 0.2 0.9 0.2 3.2 2.1 3.7 1.2 17.8 17.7 19.3 17.3 16.6 19.4 25.0 20.3 24.7 24.6 24.5 29.2 28.7 6.4 18.8 17.3 8.9 17.2 14.5 14.1 12.5 5.4 24.0 14.7 43.1 20.0 15.0 9.2 12.5 26.2 4.2 4.1 0.0 22.7 1.3 3.5 35.9 29.4 1.2 3.6 21.1 21.2 16.7 39.8 16.8 7.5 2.5 2.9 37.1 70.6 20.4 8.4 42.4 13.6 18.3 31.0 20.9 4.3 23.0 19.5 10.6 19.7 19.0 15.0 0.0 36.2 29.2 22.4 4.1 28.2 13.2 38.4 1.3 4.5 14.0 12.9 19.7 35.2 23.3 3.7 2.7 17.9 22.0 46.1 9.8 9.5 11.7 20.4 SETDB1 "ESET, KG1T, KIAA0067, KMT1E, TDRD21" ENSG00000143379 "SET domain bifurcated histone lysine methyltransferase 1" Q15047 1 150926263-150964744 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 6 "U-698: 341.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018142, HPA058484" Uncertain Supported Nucleoplasm,Vesicles Yes No "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm Vesicles "HPA018142: AB_1856757, HPA058484: AB_2683731" "unprognostic (1.07e-1)" "unprognostic (4.08e-1)" "unprognostic (8.02e-2)" "unprognostic (2.24e-3)" "unprognostic (1.65e-2)" "unprognostic (9.57e-2)" "prognostic unfavorable (8.88e-4)" "unprognostic (6.03e-2)" "unprognostic (9.94e-3)" "unprognostic (7.13e-2)" "unprognostic (1.21e-1)" "unprognostic (6.65e-2)" "prognostic unfavorable (4.25e-4)" "unprognostic (1.59e-1)" "unprognostic (3.93e-2)" "unprognostic (3.14e-2)" "unprognostic (1.14e-1)" 13.5 11.3 7.1 15.2 8.2 18.1 16.7 12.8 8.9 14.4 8.7 13.4 12.5 18.1 13.1 11.8 15.3 11.5 8.2 6.7 7.9 11.7 11.5 13.4 19.6 8.2 7.6 19.4 13.3 15.7 8.6 17.7 7.6 11.4 15.5 14.2 12.3 12.2 16.4 14.4 13.7 16.5 6.0 19.9 13.4 25.1 8.4 21.6 15.5 11.7 20.3 13.1 12.7 10.3 22.9 26.3 37.1 24.6 17.5 23.2 61.7 18.6 21.2 26.2 22.2 17.9 31.1 44.9 24.9 20.7 10.4 28.1 35.0 20.0 20.7 21.8 43.3 25.5 27.3 20.8 24.7 45.3 23.2 30.5 22.0 21.8 34.8 26.6 31.2 28.3 43.4 35.6 18.9 44.1 31.6 26.4 51.1 32.1 20.6 36.3 24.3 33.4 20.1 25.9 27.1 49.1 28.4 32.9 22.5 44.5 35.7 60.4 21.2 15.3 15.7 17.0 26.3 36.6 42.3 341.6 15.7 15.7 15.1 6.9 8.3 5.7 5.8 11.6 6.1 6.1 5.3 6.6 9.7 8.3 5.7 5.9 4.8 6.3 8.5 6.5 3.5 4.3 7.1 8.2 12.8 8.9 6.7 7.9 8.2 7.6 7.6 6.0 8.4 10.3 8.5 6.4 14.0 15.3 15.3 5.5 9.3 6.6 10.2 11.0 9.8 10.7 5.5 10.0 7.8 7.3 18.8 13.9 8.8 6.6 3.9 7.6 26.1 10.8 13.3 8.3 3.6 9.2 19.6 5.7 8.5 9.1 10.2 10.7 7.6 17.9 11.4 8.1 9.9 6.7 19.4 9.7 12.2 17.2 5.1 31.0 10.2 13.9 1.8 23.4 14.4 6.2 14.4 15.6 23.5 8.1 9.5 9.8 8.9 8.2 7.6 6.4 11.0 10.4 6.6 10.2 10.3 24.4 15.9 10.9 5.1 10.0 10.2 14.6 10.7 7.8 SETX "ALS4, AOA2, KIAA0625, SCAR1, Sen1" ENSG00000107290 Senataxin Q7Z333 9 132261356-132354986 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Differentiation, DNA damage, DNA recombination, DNA repair, Neurogenesis, Spermatogenesis" "Helicase, Hydrolase" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024105, HPA057269" Approved Supported "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Cytokinetic bridge" "HPA024105: AB_2671437, HPA057269: AB_2683389" "unprognostic (2.16e-1)" "unprognostic (5.77e-2)" "unprognostic (3.23e-1)" "unprognostic (2.03e-1)" "unprognostic (9.99e-2)" "unprognostic (2.14e-2)" "unprognostic (4.86e-2)" "unprognostic (1.64e-2)" "unprognostic (2.06e-2)" "unprognostic (1.38e-2)" "unprognostic (2.36e-1)" "unprognostic (3.32e-1)" "unprognostic (6.76e-3)" "unprognostic (2.47e-1)" "unprognostic (1.13e-1)" "unprognostic (5.64e-3)" "unprognostic (6.42e-2)" 13.7 9.5 6.2 19.9 8.8 16.8 13.9 9.8 6.3 13.2 7.7 13.1 10.6 12.7 11.1 10.6 10.9 12.7 10.5 5.1 7.8 11.9 16.7 15.4 27.4 8.7 7.0 13.0 9.2 18.3 6.0 14.3 9.6 13.0 12.8 13.2 9.0 12.7 12.9 12.3 13.2 12.8 8.0 27.6 12.9 31.9 7.7 25.4 33.0 12.8 26.3 15.7 8.5 13.2 15.1 19.9 22.5 24.4 28.3 34.1 13.5 19.6 21.9 15.6 14.6 21.1 16.8 25.6 9.4 36.9 38.3 30.2 22.8 17.0 17.0 24.6 9.9 26.9 22.7 18.4 26.5 41.8 31.2 24.0 26.2 26.6 23.6 19.1 25.4 17.8 31.7 20.0 18.3 21.8 25.9 15.8 24.2 25.4 15.4 24.2 32.6 17.2 17.1 19.5 14.0 21.4 32.4 14.2 18.2 29.7 19.7 21.2 29.3 32.5 14.0 22.1 19.0 12.2 22.0 38.6 14.9 16.3 17.8 10.5 4.4 4.7 5.3 4.1 5.6 5.5 3.9 4.1 3.3 6.9 4.2 3.7 15.1 5.2 4.9 5.0 3.2 2.3 6.2 8.8 9.8 6.3 5.1 7.8 8.7 7.0 9.6 8.0 7.7 13.2 76.2 60.9 45.7 75.1 85.6 30.2 34.6 26.6 38.7 31.2 24.1 22.7 61.3 17.2 43.9 20.2 29.2 13.7 96.8 37.6 3.9 20.0 7.6 62.7 68.0 58.7 14.5 25.5 73.7 14.7 10.6 52.9 44.4 89.7 58.2 38.3 51.4 33.0 28.8 67.3 64.8 30.6 16.2 73.1 37.6 13.8 30.7 75.5 12.4 131.2 75.8 20.7 87.6 65.9 113.0 23.2 31.9 36.1 61.8 49.3 25.6 18.5 54.4 28.7 13.1 44.9 42.5 145.2 38.5 35.1 33.5 9.4 65.9 53.7 26.9 46.4 SFRP1 "FRP, FRP-1, SARP2" ENSG00000104332 "Secreted frizzled related protein 1" Q8N474 8 41261962-41309473 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 299.3;choroid plexus: 509.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 710.9;Breast myoepithelial cells: 1158.6;Cardiomyocytes: 266.3;Leydig cells: 578.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "hTERT-RPE1: 3203.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008116, HPA064870" Approved Approved Nucleoli,Cytosol "Secreted in other tissues" Yes No 1300000 "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 35: Glandular cells - Unknown function" Nucleoli Cytosol "CAB008116: AB_2187070, HPA064870: AB_2685376" "unprognostic (1.23e-3)" "unprognostic (7.01e-2)" "unprognostic (2.14e-1)" "unprognostic (3.59e-1)" "unprognostic (7.13e-2)" "prognostic favorable (1.55e-4)" "unprognostic (1.79e-1)" "unprognostic (2.69e-3)" "unprognostic (2.15e-2)" "unprognostic (4.67e-3)" "unprognostic (3.52e-3)" "unprognostic (4.74e-2)" "unprognostic (1.72e-2)" "unprognostic (1.75e-2)" "unprognostic (1.28e-1)" "unprognostic (2.57e-1)" "prognostic unfavorable (3.12e-4)" 88.4 12.9 9.2 10.5 12.7 1.4 299.3 18.2 15.0 203.7 509.2 24.5 12.2 132.5 1.8 26.1 98.5 61.3 124.8 29.4 8.5 115.3 6.1 4.7 4.0 29.9 10.5 46.8 6.2 1.4 1.2 19.5 29.7 42.6 30.1 2.2 236.9 102.3 2.6 55.4 18.9 82.9 7.7 21.4 24.4 28.4 10.8 3.1 12.7 32.8 3.2 44.9 95.6 24.7 0.1 29.0 75.9 1.9 67.5 3.9 14.5 132.9 694.5 197.9 187.2 0.0 17.8 0.0 0.6 0.7 15.8 0.9 10.8 53.7 277.6 0.0 2.3 0.0 0.0 0.0 6.4 0.0 0.7 11.8 255.9 19.9 19.3 3203.5 6.2 0.2 0.0 0.0 3.7 0.0 0.0 0.2 205.8 0.1 0.3 0.0 15.7 0.0 422.6 0.0 4.1 18.5 5.5 0.0 41.5 264.7 0.1 2.1 1.9 0.1 19.6 0.2 18.3 0.0 0.0 0.0 0.2 0.0 279.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 12.7 18.2 15.0 29.4 8.5 29.9 10.5 29.7 7.7 10.8 24.7 8.4 0.0 0.0 2.0 1.2 11.2 134.0 1.4 147.4 1.8 710.9 1158.6 266.3 0.0 0.7 62.5 2.1 2.2 9.1 0.0 80.3 4.4 5.0 3.0 131.6 21.0 0.0 0.0 0.2 0.0 82.0 229.5 16.8 3.4 0.0 19.3 53.6 0.3 2.0 1.7 12.1 0.0 0.0 0.3 4.0 25.7 578.4 4.0 99.6 0.0 0.0 76.2 0.0 7.5 20.6 0.1 0.0 130.1 2.1 29.7 0.0 3.2 0.0 1.8 0.0 34.9 18.0 2.3 16.8 53.7 5.5 0.8 7.3 72.6 0.0 9.3 SGCE DYT11 ENSG00000127990 "Sarcoglycan epsilon" O43556 7 94524204-94656572 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 116.6;Oligodendrocyte precursor cells: 133.2;Oligodendrocytes: 116.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "gdT-cell: 2.1;memory B-cell: 4.4;naive B-cell: 6.6" "Group enriched" "Detected in many" 4 "B-cells: 6.6;T-cells: 2.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074790 Approved "Nucleoplasm,Golgi apparatus,Vesicles,Plasma membrane" Yes No 170000 "Cluster 19: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA074790: AB_2686713" "unprognostic (3.16e-3)" "unprognostic (9.06e-2)" "unprognostic (1.20e-1)" "unprognostic (1.20e-3)" "unprognostic (1.12e-1)" "prognostic unfavorable (1.61e-5)" "unprognostic (1.19e-2)" "unprognostic (2.82e-2)" "unprognostic (6.93e-2)" "unprognostic (3.37e-1)" "unprognostic (6.80e-3)" "unprognostic (9.69e-2)" "unprognostic (5.71e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.43e-1)" "unprognostic (2.04e-1)" "unprognostic (2.44e-2)" 43.2 63.4 19.9 9.4 21.6 0.4 36.5 22.1 31.6 45.1 20.9 51.6 8.0 43.2 27.1 13.3 40.7 27.6 38.9 19.6 21.0 19.5 14.4 30.5 16.7 23.2 20.6 92.2 21.5 10.9 30.9 52.7 22.4 18.0 12.8 16.8 21.1 31.6 8.5 8.2 19.2 41.8 21.9 25.1 23.8 18.5 20.4 12.8 23.9 19.8 7.2 35.6 34.6 26.7 13.5 42.5 39.6 61.8 63.7 110.8 7.1 51.3 92.3 40.7 60.4 24.9 78.0 12.8 70.4 86.5 83.7 9.4 60.0 21.6 49.1 2.2 32.7 1.4 36.9 28.3 44.0 4.3 0.0 95.5 31.1 64.8 79.3 104.9 30.8 0.0 0.1 93.7 43.5 42.6 0.0 0.0 32.8 8.0 29.0 19.8 51.0 25.8 78.6 13.6 26.2 20.8 0.0 52.2 65.1 44.2 17.6 0.8 0.0 131.1 45.1 11.8 81.7 50.8 67.9 14.8 51.4 0.2 74.2 0.7 0.0 0.1 2.1 0.0 0.8 4.4 0.6 1.0 0.0 6.6 0.2 0.7 0.3 1.0 0.1 0.2 0.2 0.3 19.9 21.6 22.1 31.6 19.6 21.0 23.2 20.6 22.4 21.9 20.4 26.7 39.2 70.5 33.3 66.9 6.1 5.0 18.4 16.8 1.8 18.6 9.7 44.4 18.6 30.0 28.3 20.2 4.2 90.2 1.4 0.0 5.9 42.5 1.6 4.0 17.1 18.8 1.2 0.4 85.2 4.3 26.1 116.6 1.5 6.6 2.5 37.3 58.2 11.2 6.3 20.2 68.5 0.1 12.2 2.5 7.3 3.7 75.5 1.4 51.6 15.9 0.0 31.5 0.0 133.2 116.3 2.1 0.0 58.3 2.6 5.5 0.0 14.1 13.7 30.3 85.5 68.0 60.7 17.1 13.0 0.9 4.0 82.8 2.7 44.0 0.0 2.2 SGF29 "CCDC101, FLJ32446, TDRD29" ENSG00000176476 "SAGA complex associated factor 29" Q96ES7 16 28553915-28591790 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Early spermatids: 222.2;Late spermatids: 384.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052590, HPA053608" Enhanced Approved Nucleoplasm,Nucleoli Yes No "Cluster 26: Non-specific - Mitochondria" "Cluster 23: Testis - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 34: Spermatids - Unknown function" Nucleoli Nucleoplasm "HPA052590: AB_2681875, HPA053608: AB_2682205" "unprognostic (1.38e-2)" "prognostic favorable (4.77e-4)" "unprognostic (1.73e-1)" "unprognostic (2.46e-3)" "unprognostic (2.80e-2)" "unprognostic (7.27e-3)" "unprognostic (1.48e-1)" "prognostic favorable (3.37e-4)" "unprognostic (1.98e-1)" "unprognostic (1.41e-1)" "prognostic favorable (2.99e-4)" "unprognostic (2.96e-1)" "unprognostic (1.35e-2)" "unprognostic (1.66e-1)" "unprognostic (2.19e-1)" "unprognostic (1.76e-1)" "unprognostic (5.42e-3)" 16.8 16.1 13.6 11.2 15.6 12.4 16.5 16.7 14.6 26.8 13.8 28.0 12.8 29.1 9.5 12.0 27.6 9.1 15.3 13.4 14.9 11.1 19.9 14.0 16.9 15.2 14.4 33.3 25.6 10.7 10.3 7.1 15.4 16.4 7.2 7.8 16.6 16.7 51.1 16.0 18.8 12.0 14.9 16.2 19.8 43.0 14.6 14.1 17.6 19.8 10.2 23.5 16.4 16.8 13.1 21.3 16.3 10.5 10.6 10.9 29.5 8.5 9.6 21.7 20.2 24.6 11.5 39.1 21.1 6.7 13.2 15.0 12.4 15.4 6.1 12.8 24.0 24.3 12.9 33.7 27.1 22.1 26.1 11.5 20.0 13.1 13.2 11.7 8.3 24.5 20.8 19.4 7.9 43.4 25.5 43.2 22.7 9.6 20.5 38.9 10.6 34.2 11.3 19.5 26.3 12.2 13.3 25.3 15.0 5.8 20.7 18.4 5.9 15.4 12.9 9.2 15.3 22.4 35.7 22.7 10.9 36.9 12.5 20.6 47.0 50.0 53.6 41.8 65.2 57.9 74.2 65.8 47.6 65.9 84.1 66.3 13.4 55.1 33.7 71.4 78.3 58.7 13.6 15.6 16.7 14.6 13.4 14.9 15.2 14.4 15.4 14.9 14.6 16.8 11.2 16.0 16.7 0.0 20.0 0.0 18.1 0.0 32.5 5.5 12.5 21.1 0.0 12.8 7.4 18.4 14.6 17.3 27.1 7.9 9.8 12.6 222.2 8.5 10.1 8.7 3.6 17.1 0.0 12.9 11.8 12.7 10.2 7.7 6.3 16.9 11.0 17.3 14.2 0.0 0.0 8.8 0.0 12.9 0.0 384.4 30.7 13.5 0.0 0.0 17.1 11.8 22.6 0.0 0.0 10.1 15.7 21.8 16.7 9.5 40.1 23.7 6.6 14.1 19.7 18.3 13.0 10.5 30.9 17.0 0.0 21.1 21.0 14.8 11.9 12.0 SGO1 "NY-BR-85, SGOL1" ENSG00000129810 "Shugoshin 1" Q5FBB7 3 20160593-20186206 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.7;lymphoid tissue: 13.0;testis: 6.7" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 16.5;Extravillous trophoblasts: 42.6;Granulosa cells: 20.3;Hofbauer cells: 10.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 5 "basophil: 10.0;memory B-cell: 8.8;naive B-cell: 8.9;plasmacytoid DC: 4.1;T-reg: 2.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035501, HPA069302, HPA069857" Enhanced Enhanced Nucleoplasm,Kinetochore,Cytosol Yes Yes "Cluster 37: B-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Kinetochore, Cytosol" "HPA035501: AB_2732469, HPA069302: , HPA069857: AB_2686214" "unprognostic (6.87e-3)" "unprognostic (5.01e-2)" "unprognostic (2.25e-2)" "unprognostic (8.93e-3)" "unprognostic (2.51e-2)" "unprognostic (4.10e-2)" "unprognostic (2.55e-6)" "unprognostic (9.49e-3)" "unprognostic (2.45e-2)" "unprognostic (3.69e-2)" "unprognostic (1.65e-4)" "unprognostic (1.52e-2)" "unprognostic (0.00e+0)" "unprognostic (2.29e-2)" "unprognostic (4.95e-2)" "unprognostic (4.14e-1)" "unprognostic (1.64e-1)" 0.3 0.1 0.3 3.3 0.7 8.7 0.5 0.9 0.5 0.4 0.0 2.1 2.3 0.4 0.0 1.9 0.1 0.4 0.1 0.3 0.4 0.3 0.6 0.3 6.2 0.8 0.6 0.2 0.1 0.2 0.0 1.7 0.6 0.2 2.8 0.1 0.4 0.1 0.1 1.1 2.5 1.0 0.3 1.4 1.5 6.7 0.6 13.0 0.2 0.0 6.6 0.9 0.7 1.2 20.3 23.9 29.9 18.5 1.4 2.6 20.2 21.3 10.1 31.2 33.6 16.5 24.0 30.7 10.6 8.6 21.2 11.4 28.7 11.3 37.6 40.9 19.6 34.6 15.6 12.8 0.2 32.0 28.8 0.3 0.9 33.3 13.1 4.0 18.5 34.9 31.3 52.2 24.6 19.4 52.4 15.4 30.0 20.3 17.0 31.8 38.4 17.7 7.5 14.9 14.2 15.4 23.6 27.2 13.1 22.7 18.2 21.3 4.7 22.5 27.3 20.5 43.3 22.8 57.4 35.2 12.5 31.1 35.0 10.0 0.1 1.4 0.2 0.2 0.1 8.8 0.6 0.7 0.3 8.9 0.2 0.3 1.4 0.3 0.2 4.1 2.6 0.6 0.3 0.7 0.9 0.5 0.3 0.4 0.8 0.6 0.6 0.3 0.6 1.2 0.1 0.0 0.5 0.0 1.9 0.0 0.0 0.0 0.0 0.0 2.0 3.4 0.0 0.0 0.0 1.8 0.0 16.5 1.5 0.0 0.0 1.1 0.0 2.3 1.6 1.2 0.0 0.0 0.0 1.8 42.6 3.3 0.0 2.9 1.3 20.3 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 2.6 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 4.9 1.0 4.3 0.0 0.0 SH2D3A NSP1 ENSG00000125731 "SH2 domain containing 3A" Q9BRG2 19 6752160-6767463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 32.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 117.9;Pancreatic endocrine cells: 81.3;Urothelial cells: 87.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 43.2;HaCaT: 34.2;HBEC3-KT: 67.4" "Not detected" "Not detected" "HPA035722, HPA064382" Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes NA "Cluster 30: Non-specific - Translation" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Microtubules "Nucleoplasm, Cytokinetic bridge" "HPA035722: AB_10670024, HPA064382: AB_2685251" "unprognostic (3.32e-2)" "unprognostic (5.48e-2)" "unprognostic (1.82e-2)" "unprognostic (1.39e-1)" "unprognostic (1.84e-1)" "unprognostic (1.09e-1)" "unprognostic (3.96e-1)" "unprognostic (2.60e-3)" "unprognostic (3.63e-1)" "unprognostic (8.41e-2)" "unprognostic (6.48e-3)" "prognostic unfavorable (6.21e-4)" "prognostic favorable (1.42e-4)" "unprognostic (7.31e-2)" "unprognostic (1.74e-1)" "unprognostic (1.32e-3)" "unprognostic (1.81e-3)" 0.9 0.4 0.2 4.6 0.2 3.4 7.5 0.1 0.6 8.0 0.5 12.8 14.3 1.2 1.0 32.5 4.3 3.5 0.6 0.1 0.1 19.6 2.6 10.8 5.2 0.4 0.2 0.8 19.7 5.9 2.8 5.9 0.2 18.1 5.4 0.9 18.7 4.1 1.5 27.6 14.4 0.3 0.2 5.7 14.2 4.4 0.3 3.3 13.0 0.0 4.1 9.1 17.0 0.5 43.2 6.2 0.1 0.2 0.0 0.0 22.6 0.3 0.0 0.0 0.0 20.3 30.8 6.6 19.6 0.0 0.0 34.2 2.3 67.4 0.0 3.6 6.6 0.3 6.9 2.6 0.1 0.6 8.6 0.0 30.3 0.0 5.9 0.8 0.0 14.8 7.3 14.3 0.0 15.3 3.2 0.2 1.6 21.5 12.0 1.2 0.1 24.8 11.5 31.4 0.0 0.2 2.3 31.7 0.1 1.0 22.0 0.4 0.7 0.7 2.2 0.5 0.4 14.1 15.8 9.2 0.2 4.8 0.3 0.1 0.0 0.0 2.6 0.1 4.2 3.6 5.9 5.2 0.1 5.6 7.7 4.2 0.1 1.8 0.1 0.4 3.2 0.9 0.2 0.2 0.1 0.6 0.1 0.1 0.4 0.2 0.2 0.2 0.3 0.5 0.7 19.2 14.2 0.3 25.8 30.7 117.9 51.4 25.0 4.1 13.6 11.4 1.9 40.0 43.9 40.5 10.4 23.8 7.7 46.6 1.9 54.1 1.6 15.4 2.9 2.8 12.1 7.8 0.1 37.1 52.8 2.6 50.0 24.9 5.7 0.3 1.8 2.9 3.6 0.0 0.2 37.9 28.5 0.6 10.3 0.8 0.6 2.2 3.6 0.0 4.2 0.8 14.4 0.0 0.1 81.3 69.7 0.0 8.0 58.6 53.9 13.1 27.0 4.6 0.0 2.2 3.5 8.7 11.4 17.6 39.9 10.8 18.0 1.1 32.0 87.9 SH3GL2 "CNSA2, EEN-B1, SH3D2A, SH3P4" ENSG00000107295 "SH3 domain containing GRB2 like 2, endophilin A1" Q99962 9 17579066-17797124 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 123.8;retina: 75.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 89.4;Excitatory neurons: 390.8;Inhibitory neurons: 140.9" "Cancer enhanced" "Detected in many" "glioma: 8.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 9.3;HeLa: 21.1;JURKAT: 18.7;RT4: 41.8;SCLC-21H: 26.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010056, HPA026685, HPA063573" Enhanced Supported Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes No "Cluster 6: Brain - Smell perception" "Cluster 15: RT4 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB010056: AB_628099, HPA026685: AB_1856817, HPA063573: AB_2685045" "unprognostic (4.78e-2)" "unprognostic (3.24e-2)" "unprognostic (1.68e-2)" "unprognostic (5.05e-5)" "unprognostic (4.23e-2)" "unprognostic (3.40e-1)" "unprognostic (1.21e-1)" "unprognostic (5.90e-2)" "unprognostic (3.90e-1)" "unprognostic (5.07e-3)" "unprognostic (8.76e-3)" "unprognostic (1.26e-1)" "prognostic favorable (6.68e-12)" "unprognostic (2.65e-2)" "unprognostic (8.29e-2)" "unprognostic (2.25e-2)" "unprognostic (8.44e-2)" 0.3 0.2 63.0 0.1 69.0 0.0 0.1 92.3 123.8 2.3 1.9 0.5 0.2 2.2 1.2 0.5 2.0 0.0 4.3 77.7 26.6 16.8 0.2 1.1 0.0 27.9 28.5 1.8 3.0 0.3 26.2 0.0 25.9 1.8 0.6 75.0 0.1 0.1 0.1 0.1 0.5 1.7 29.3 0.1 8.7 6.5 41.1 0.7 1.5 0.0 0.0 4.3 0.4 55.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 2.0 7.5 0.8 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 9.3 0.0 21.1 0.0 0.1 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 18.7 0.0 0.1 0.0 0.0 0.1 0.2 2.5 0.0 2.4 0.0 0.0 0.0 0.0 41.8 26.5 0.0 0.3 0.0 0.8 0.8 0.0 0.0 0.0 0.0 2.2 0.0 1.5 0.0 0.4 0.0 1.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 63.0 69.0 92.3 123.8 77.7 26.6 27.9 28.5 25.9 29.3 41.1 55.5 0.0 0.0 0.0 16.3 0.0 0.1 0.4 0.0 0.0 89.4 0.1 0.0 1.8 0.0 0.0 7.3 22.9 0.0 0.0 0.1 11.7 0.0 16.7 0.2 0.1 0.3 5.3 0.0 390.8 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.1 13.5 140.9 0.7 0.0 0.0 0.3 47.4 1.2 0.1 0.0 13.1 0.1 9.0 0.0 41.7 10.2 0.2 0.1 0.4 0.0 2.2 0.0 22.2 0.0 28.0 0.0 0.0 0.1 2.4 6.1 0.0 0.0 0.1 0.0 1.2 0.7 0.4 SH3RF3 "FLJ00204, POSH2, SH3MD4" ENSG00000172985 "SH3 domain containing ring finger 3" Q8TEJ3 2 109129205-109504634 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Astrocytes: 47.0;Excitatory neurons: 108.3;Inhibitory neurons: 160.9;Microglial cells: 164.9;Oligodendrocyte precursor cells: 42.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 19.8;RPMI-8226: 20.5;TIME: 23.2;U-266/84: 28.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA044822, HPA048444" Approved Supported Nucleoplasm Yes No "Cluster 47: Non-specific - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA044822: AB_2679103, HPA048444: AB_2680396" "unprognostic (1.97e-1)" "unprognostic (8.84e-3)" "unprognostic (8.04e-2)" "unprognostic (1.91e-1)" "unprognostic (2.55e-1)" "unprognostic (1.78e-1)" "unprognostic (8.00e-2)" "unprognostic (1.76e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (2.33e-4)" "unprognostic (4.57e-2)" "unprognostic (1.95e-1)" "unprognostic (3.54e-2)" "unprognostic (4.94e-2)" "unprognostic (2.72e-1)" "unprognostic (2.79e-2)" "unprognostic (1.39e-2)" 6.1 6.7 4.7 3.0 6.1 0.8 4.3 1.3 6.5 5.5 1.6 5.6 1.1 3.7 0.7 2.8 4.8 4.4 6.0 6.3 3.2 6.8 1.1 7.2 2.1 3.0 4.5 3.2 2.0 0.5 1.9 5.2 2.8 4.7 1.4 0.6 1.6 4.4 5.7 3.1 3.3 3.8 3.1 2.1 2.9 4.2 3.9 3.2 2.5 7.3 1.2 5.5 4.2 3.5 0.0 0.1 0.1 2.2 9.0 6.9 0.0 4.2 12.2 3.1 1.1 1.1 0.0 0.0 3.1 3.1 0.7 0.0 0.2 1.8 1.3 0.0 4.2 0.0 0.2 0.0 19.8 0.1 0.0 12.0 2.9 14.1 6.3 1.8 11.4 2.2 0.0 11.7 7.3 0.0 0.0 6.5 1.1 0.0 12.0 2.6 0.0 20.5 0.0 0.0 0.7 2.5 0.0 0.0 0.4 0.1 0.2 0.0 23.2 4.0 12.0 11.5 5.5 4.0 28.6 0.0 0.0 6.3 5.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.7 6.1 1.3 6.5 6.3 3.2 3.0 4.5 2.8 3.1 3.9 3.5 5.3 0.0 0.0 47.0 0.2 1.9 0.4 0.2 1.8 0.5 0.6 0.5 10.7 0.0 0.7 0.0 0.0 0.0 1.5 0.1 0.0 1.1 2.6 9.4 9.6 6.7 1.8 0.0 108.3 0.2 0.2 4.8 0.0 1.1 0.0 0.2 7.5 0.0 4.7 10.1 160.9 0.8 0.0 2.5 1.5 5.2 2.1 1.2 5.4 164.9 0.0 1.7 0.0 42.3 1.9 0.1 0.0 3.0 1.6 0.2 0.0 0.6 2.1 0.0 13.1 3.2 6.8 0.7 9.6 0.8 0.9 0.1 0.5 2.3 0.1 0.0 SHCBP1 "FLJ22009, PAL" ENSG00000171241 "SHC binding and spindle associated 1" Q8NEM2 16 46578591-46621379 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.4;lymphoid tissue: 10.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 36.2;Extravillous trophoblasts: 28.7;Plasma cells: 38.3;Spermatocytes: 33.7;Spermatogonia: 23.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA048876 Uncertain Approved "Nuclear bodies,Microtubules,Midbody,Mitotic spindle" Yes Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies" "Microtubules, Midbody, Mitotic spindle" "HPA048876: AB_2680542" "unprognostic (2.44e-3)" "unprognostic (1.13e-1)" "unprognostic (2.98e-2)" "unprognostic (2.74e-1)" "unprognostic (2.54e-2)" "unprognostic (2.35e-2)" "unprognostic (2.96e-4)" "unprognostic (2.26e-3)" "unprognostic (5.35e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (4.47e-5)" "unprognostic (4.81e-2)" "unprognostic (2.22e-16)" "unprognostic (3.59e-2)" "unprognostic (3.86e-2)" "unprognostic (2.66e-1)" "unprognostic (2.66e-1)" 0.7 0.5 0.5 5.1 0.5 17.4 0.9 1.2 0.6 0.6 0.4 1.9 1.2 0.6 0.6 3.5 0.2 0.6 1.0 0.4 0.2 5.4 0.2 1.0 9.8 0.4 0.3 0.3 0.2 0.2 0.2 2.4 0.4 0.3 2.2 0.2 0.8 0.2 1.5 3.3 1.5 1.7 0.1 4.4 0.9 5.2 0.5 8.8 0.3 0.2 10.6 1.2 1.2 0.7 33.8 30.8 11.9 15.3 3.1 6.2 16.2 60.7 24.6 59.2 26.8 14.6 20.8 28.0 30.2 28.8 26.8 21.0 29.3 21.7 73.8 17.7 17.2 28.2 25.8 30.3 0.1 28.5 35.4 1.2 1.6 45.9 18.1 5.9 33.0 14.9 12.7 28.3 69.7 21.5 24.0 23.7 10.0 17.2 31.6 45.4 89.9 44.8 13.7 9.4 5.0 7.2 46.0 23.7 11.1 11.4 13.0 23.4 16.1 43.9 28.7 43.5 54.0 24.9 36.7 46.7 21.4 31.3 45.8 0.2 0.3 0.6 0.2 0.5 0.0 1.7 0.3 0.1 0.3 1.2 0.0 0.1 0.4 0.1 2.4 0.7 1.2 1.1 0.5 0.5 1.2 0.6 0.4 0.2 0.4 0.3 0.4 0.1 0.5 0.7 0.2 0.0 1.1 1.3 7.1 1.7 0.7 1.2 0.0 0.3 0.6 1.1 1.9 1.5 1.4 0.0 0.0 11.3 0.8 1.9 0.0 0.2 8.4 0.7 1.7 1.7 0.0 36.2 2.1 0.0 28.7 3.7 4.1 1.5 0.0 7.6 1.8 0.3 12.6 0.0 0.7 2.2 2.0 4.5 3.3 2.3 0.6 4.0 1.8 2.8 2.8 0.8 0.0 1.0 0.5 0.1 0.1 0.4 38.3 0.5 0.4 0.1 0.1 0.3 0.0 0.5 6.3 33.7 23.7 3.6 0.6 3.7 2.2 0.8 3.4 1.1 SKA3 "C13orf3, MGC4832, RAMA1" ENSG00000165480 "Spindle and kinetochore associated complex subunit 3" Q8IX90 13 21153595-21176552 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.7;lymphoid tissue: 12.1;testis: 6.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 12.8;Extravillous trophoblasts: 21.0;Spermatocytes: 21.7;Spermatogonia: 18.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039272, HPA039356, HPA061534" Approved Supported "Mitotic spindle,Centrosome,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Mitotic spindle" "Centrosome, Cytosol" "HPA039272: AB_10805359, HPA039356: AB_10805475, HPA061534: " "unprognostic (3.46e-2)" "unprognostic (7.21e-2)" "unprognostic (2.15e-1)" "unprognostic (1.62e-2)" "unprognostic (2.04e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (9.73e-6)" "unprognostic (2.03e-3)" "prognostic unfavorable (8.71e-4)" "unprognostic (2.03e-1)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.39e-2)" "unprognostic (0.00e+0)" "unprognostic (2.24e-3)" "unprognostic (1.81e-1)" "unprognostic (1.22e-1)" "unprognostic (1.32e-1)" 0.2 0.1 0.2 2.5 0.2 4.7 0.8 0.1 0.3 0.2 0.0 1.7 1.0 0.5 0.0 1.9 0.2 0.4 0.0 0.5 0.2 0.1 0.2 0.2 4.3 0.2 0.2 0.0 0.0 0.0 0.0 1.6 0.2 0.0 3.0 0.0 0.2 0.0 0.0 1.8 2.1 1.1 0.2 0.7 1.0 6.3 0.3 12.1 0.1 0.1 3.7 0.4 0.5 0.2 26.1 13.0 25.8 20.5 0.9 5.1 19.1 35.0 14.8 42.1 28.7 23.4 27.8 35.6 10.0 19.3 18.5 24.4 34.4 15.2 54.7 30.3 15.9 47.3 7.7 12.7 0.0 39.5 17.7 1.5 1.0 34.9 15.4 4.2 20.7 30.6 26.3 14.2 33.9 21.0 60.7 37.8 27.9 42.8 23.8 36.5 50.3 15.8 12.2 9.9 30.1 11.1 11.8 17.1 8.1 17.9 15.3 33.5 8.7 16.0 23.8 17.0 43.9 9.0 19.7 34.5 4.4 31.1 51.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.5 0.1 0.2 0.2 0.1 0.3 0.5 0.2 0.2 0.2 0.2 0.2 0.3 0.2 0.4 0.0 0.0 0.0 2.6 2.0 0.7 2.4 0.0 0.1 0.9 0.8 0.8 0.0 1.8 0.0 0.0 8.7 1.0 2.1 0.0 1.2 6.3 2.8 0.9 1.4 0.0 12.8 0.8 1.3 21.0 2.1 1.5 1.6 0.0 5.8 1.8 0.4 5.5 0.0 0.6 1.8 2.0 1.9 2.9 7.7 1.5 1.6 0.0 1.9 0.8 0.3 3.1 0.0 0.2 1.0 1.6 1.2 8.5 0.3 0.4 0.6 2.0 0.4 0.0 0.3 2.3 21.7 18.2 5.8 2.8 2.2 1.2 0.5 5.0 0.7 SKIV2L "170A, DDX13, HLP, SKI2W, SKIV2, SKIV2L1" ENSG00000204351 "Ski2 like RNA helicase" Q15477 6 31959117-31969751 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 42.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047122, HPA051959, HPA054419" Uncertain Approved "Nucleoplasm,Nuclear bodies,Mitotic spindle,Cytosol" Yes NA "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 29: U-266 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nuclear bodies" "Mitotic spindle, Cytosol" "HPA047122: , HPA051959: AB_2681672, HPA054419: AB_2682482" "unprognostic (1.43e-1)" "unprognostic (5.75e-2)" "unprognostic (3.41e-2)" "unprognostic (1.66e-2)" "unprognostic (6.43e-2)" "unprognostic (7.03e-2)" "prognostic unfavorable (6.58e-4)" "unprognostic (3.36e-2)" "unprognostic (2.14e-2)" "unprognostic (7.75e-2)" "unprognostic (7.99e-3)" "unprognostic (1.53e-3)" "prognostic unfavorable (3.02e-7)" "unprognostic (6.77e-2)" "unprognostic (2.23e-1)" "unprognostic (1.20e-1)" "unprognostic (9.06e-2)" 21.9 33.1 0.0 5.2 0.3 4.1 21.6 0.0 0.4 26.5 0.0 25.1 10.5 22.6 9.4 23.0 25.0 0.0 22.0 0.0 0.1 24.0 54.7 22.2 3.4 0.0 0.5 24.6 25.7 2.4 39.7 2.6 0.0 31.9 2.4 2.1 22.4 3.2 20.4 20.2 31.2 5.7 0.0 40.6 27.6 16.6 0.1 4.3 27.7 5.3 2.7 23.6 20.9 0.0 0.2 12.7 13.3 0.0 16.5 11.8 27.1 10.9 11.7 13.6 13.2 0.4 0.0 0.0 26.0 25.5 13.2 11.9 0.0 30.8 9.9 14.8 15.7 0.0 0.0 0.2 0.0 0.1 0.2 28.3 17.9 0.1 0.0 12.7 0.0 19.3 0.0 13.6 0.0 0.0 0.0 0.3 20.6 0.0 0.0 0.3 0.0 0.0 11.2 0.0 0.0 0.0 23.6 0.0 17.6 11.5 0.0 15.7 12.8 16.0 7.2 18.7 0.2 42.2 35.7 12.0 20.4 0.1 0.0 0.3 0.5 0.2 1.5 1.4 1.1 0.2 0.7 0.3 1.1 0.9 0.8 0.8 0.1 0.0 2.2 0.5 0.2 0.4 0.0 0.3 0.0 0.4 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.0 6.4 16.0 11.3 10.1 13.3 2.8 5.0 7.9 11.4 5.0 9.3 5.1 8.5 10.0 8.8 7.3 8.4 12.6 12.7 19.7 1.9 9.5 3.1 7.7 7.9 7.9 12.6 6.5 7.2 8.6 7.9 7.4 28.1 6.3 8.2 10.8 8.6 19.4 9.2 0.0 5.0 13.2 8.2 6.3 4.1 1.5 9.3 7.8 7.2 2.8 10.2 4.9 18.6 3.0 4.8 9.4 16.0 6.0 20.2 5.9 25.5 6.9 16.5 8.3 0.0 4.1 10.2 4.7 7.5 6.6 3.7 12.4 14.4 12.3 11.0 5.2 SLBP HBP ENSG00000163950 "Stem-loop binding protein" Q14493 4 1692731-1712344 "Predicted intracellular proteins" "mRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 263.6;Spermatogonia: 294.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019254, HPA061670" Supported Supported Nucleoplasm,Nucleoli,Cytosol Yes Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli, Cytosol" "HPA019254: AB_1856951, HPA061670: AB_2684581" "unprognostic (1.81e-2)" "unprognostic (6.80e-3)" "unprognostic (2.05e-2)" "unprognostic (1.59e-1)" "unprognostic (1.94e-1)" "unprognostic (7.09e-3)" "prognostic unfavorable (2.29e-5)" "unprognostic (5.53e-2)" "unprognostic (1.94e-2)" "unprognostic (1.13e-2)" "unprognostic (9.81e-3)" "unprognostic (9.55e-3)" "unprognostic (4.58e-2)" "unprognostic (7.31e-2)" "unprognostic (1.95e-1)" "unprognostic (1.44e-1)" "unprognostic (7.07e-2)" 29.9 26.4 38.6 37.6 40.2 114.2 26.7 38.0 65.7 28.4 34.4 30.6 23.9 27.3 32.9 35.9 27.6 21.9 18.4 40.9 43.6 35.1 33.9 27.2 71.7 36.4 39.1 28.0 24.4 24.0 26.7 42.0 39.3 22.8 30.6 17.1 25.6 25.3 22.6 37.7 25.6 28.8 37.7 28.3 26.9 63.1 41.8 53.5 27.3 19.2 69.5 35.0 28.0 41.1 132.7 53.9 76.6 80.7 65.3 70.0 81.9 120.1 92.5 131.4 133.8 120.3 144.7 180.6 67.4 96.0 150.9 77.8 147.0 103.0 154.1 75.4 98.5 215.9 63.3 123.6 82.6 208.3 102.8 55.0 84.7 98.1 67.3 74.4 76.5 108.8 172.7 170.3 163.2 52.8 314.6 200.6 97.4 136.7 108.6 241.1 126.3 105.3 131.0 99.5 86.1 69.3 95.4 59.6 69.5 96.8 99.0 127.7 66.3 108.0 63.8 116.1 180.4 107.4 192.2 428.3 99.6 176.0 106.0 25.7 65.4 47.5 47.1 49.7 43.3 51.6 59.7 64.8 50.6 37.8 50.6 49.6 95.8 46.3 44.8 42.2 77.9 75.4 38.6 40.2 38.0 65.7 40.9 43.6 36.4 39.1 39.3 37.7 41.8 41.1 35.2 16.0 18.8 7.2 96.3 105.2 96.3 38.8 61.5 19.4 35.9 34.0 8.2 27.1 23.6 36.8 25.0 166.3 80.5 28.8 107.6 50.6 75.9 38.8 34.9 36.1 35.9 146.0 14.6 31.3 51.8 49.1 53.5 55.5 23.5 45.9 30.0 27.0 81.3 25.2 15.1 33.6 44.7 36.8 58.6 41.6 44.1 60.3 65.8 6.5 64.4 27.4 43.3 9.0 14.4 38.7 25.3 44.0 94.2 88.6 22.5 55.4 16.3 13.6 13.1 46.3 43.8 263.6 294.0 84.1 105.8 44.7 96.6 33.2 44.1 76.5 SLC16A4 "MCT4, MCT5" ENSG00000168679 "Solute carrier family 16 member 4" O15374 1 110362851-110391082 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 124.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 71.7;Proximal tubular cells: 192.3" "Cancer enhanced" "Detected in all" "renal cancer: 35.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.5" "Lineage enriched" "Detected in single" 4 "B-cells: 1.5" "Cell line enhanced" "Detected in many" "BEWO: 20.4;BJ hTERT+: 20.7;CAPAN-2: 30.8;HHSteC: 19.2;hTERT-RPE1: 42.6;SK-MEL-30: 30.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046986, HPA060163" Approved Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 43: B-cells - Humoral immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Microtubules, Cytosol" "Cytokinetic bridge" "HPA046986: AB_2679892, HPA060163: " "unprognostic (2.04e-1)" "unprognostic (1.69e-1)" "unprognostic (2.56e-1)" "unprognostic (2.77e-3)" "unprognostic (1.53e-1)" "unprognostic (2.22e-1)" "unprognostic (2.00e-2)" "unprognostic (7.94e-2)" "unprognostic (2.29e-1)" "unprognostic (1.81e-1)" "unprognostic (1.70e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.69e-4)" "unprognostic (3.68e-2)" "unprognostic (9.16e-2)" "unprognostic (1.71e-2)" "unprognostic (9.46e-2)" 4.9 2.9 2.7 4.6 3.1 1.0 6.9 5.8 4.4 4.2 15.4 3.6 9.5 3.0 22.4 2.7 4.0 13.7 4.6 3.5 4.1 124.1 16.3 9.2 3.4 4.1 3.1 21.4 0.9 0.4 3.8 28.6 3.9 3.8 1.6 2.3 3.6 5.8 1.3 1.3 11.4 3.4 4.1 2.7 2.7 5.2 3.0 0.6 8.5 3.9 1.1 7.9 3.5 4.2 0.4 9.8 2.3 2.7 6.3 12.9 20.4 5.3 20.7 1.8 5.3 3.1 30.8 0.6 5.7 17.1 0.1 0.5 0.1 1.9 1.9 0.5 2.5 0.5 2.7 3.3 19.2 0.9 0.5 10.0 0.3 3.0 0.2 42.6 4.1 0.8 0.5 1.2 3.3 1.0 0.4 0.6 0.9 0.0 0.3 0.2 1.3 0.1 3.7 0.4 1.2 0.9 0.6 9.8 30.6 9.0 0.7 0.1 0.4 1.4 0.7 0.3 1.5 0.5 0.1 1.6 1.1 0.4 6.1 0.0 0.2 0.1 0.1 0.0 0.0 1.5 0.1 0.0 0.0 0.3 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.1 2.7 3.1 5.8 4.4 3.5 4.1 4.1 3.1 3.9 4.1 3.0 4.2 1.9 12.8 20.8 2.3 5.8 3.1 6.1 11.2 1.2 11.5 14.7 6.5 1.1 11.5 6.8 71.7 6.2 39.5 5.8 0.9 3.9 2.7 0.5 3.3 6.8 4.6 3.5 2.7 8.2 0.9 34.6 18.2 1.5 3.3 5.1 5.2 4.2 5.0 4.2 3.3 7.1 0.9 4.1 1.6 3.0 2.2 18.0 1.8 10.6 15.0 1.8 2.4 9.2 2.5 4.7 1.9 1.2 11.7 1.2 3.1 38.4 192.3 3.5 20.1 0.0 4.5 5.4 3.4 1.9 0.5 3.7 35.2 3.9 7.0 1.4 7.2 SLC25A42 MGC26694 ENSG00000181035 "Solute carrier family 25 member 42" Q86VD7 19 19063994-19113030 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 82.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 67.7;Hepatocytes: 52.1;Proximal tubular cells: 39.6;Rod photoreceptor cells: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 2.7;MAIT T-cell: 1.4;memory B-cell: 3.3;memory CD4 T-cell: 1.5;memory CD8 T-cell: 2.4;naive B-cell: 3.2;naive CD4 T-cell: 1.0;naive CD8 T-cell: 1.4;NK-cell: 1.8;T-reg: 1.7" "Group enriched" "Detected in many" 6 "B-cells: 3.3;NK-cells: 1.8;T-cells: 2.7" "Cell line enhanced" "Detected in many" "K-562: 20.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049449 Approved Supported Mitochondria Yes No "Cluster 43: B-cells - Humoral immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 56: Bipolar cells - Visual perception" Mitochondria "HPA049449: AB_2680772" "unprognostic (2.27e-1)" "prognostic favorable (5.04e-4)" "unprognostic (5.79e-2)" "unprognostic (5.67e-2)" "unprognostic (1.35e-1)" "unprognostic (3.42e-3)" "unprognostic (1.27e-3)" "prognostic favorable (4.11e-4)" "unprognostic (6.89e-2)" "unprognostic (2.73e-1)" "unprognostic (1.37e-3)" "unprognostic (3.04e-2)" "unprognostic (5.29e-3)" "unprognostic (1.76e-1)" "unprognostic (2.39e-2)" "unprognostic (4.17e-2)" "unprognostic (2.03e-2)" 8.5 7.5 17.2 4.3 16.9 8.3 7.9 14.5 18.3 13.1 16.7 8.4 5.1 10.1 3.7 5.2 12.5 3.5 15.8 17.9 16.9 34.1 82.0 6.6 9.0 14.9 15.2 16.9 11.3 6.0 14.4 2.6 14.7 9.9 2.4 8.4 9.2 5.2 46.5 6.7 9.3 4.9 13.9 12.7 8.3 7.0 18.0 8.1 25.6 32.6 7.5 9.6 9.1 13.9 7.3 1.0 1.8 3.2 6.8 5.6 2.8 3.5 5.2 5.3 6.0 1.4 14.3 5.2 8.0 3.3 5.3 1.3 3.7 2.9 3.0 1.3 7.0 1.8 2.0 11.8 5.4 0.8 3.6 5.6 2.0 4.0 2.4 4.3 2.4 16.8 20.9 9.2 2.8 6.6 9.0 8.4 1.0 2.0 7.4 6.8 3.2 10.2 2.1 1.3 2.0 1.5 3.7 0.1 1.6 2.4 6.5 4.1 2.2 3.9 2.2 8.2 3.4 10.7 6.2 4.1 4.1 11.2 2.0 0.0 0.1 0.1 2.7 0.3 1.4 3.3 1.5 2.4 0.2 3.2 1.0 1.4 0.0 1.8 0.3 0.4 1.7 0.9 17.2 16.9 14.5 18.3 17.9 16.9 14.9 15.2 14.7 13.9 18.0 13.9 4.6 0.0 13.1 12.4 14.2 3.2 2.8 3.3 2.8 67.7 5.9 6.6 9.7 5.7 4.1 9.2 18.8 7.7 16.5 3.1 13.7 1.5 1.2 2.5 5.4 4.1 8.4 13.7 18.6 3.1 3.8 5.1 4.1 3.6 3.8 8.3 5.3 52.1 1.8 3.3 25.0 3.8 6.1 0.6 1.9 1.6 5.0 1.4 3.6 6.5 1.3 12.5 32.0 16.1 8.6 2.5 4.6 6.4 16.4 2.4 9.2 39.6 3.0 41.4 6.6 9.6 5.8 10.6 7.6 0.9 2.8 4.7 10.9 8.0 3.1 1.7 SLC27A3 "ACSVL3, FATP3, MGC4365" ENSG00000143554 "Solute carrier family 27 member 3" Q5K4L6 1 153774354-153780157 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 7.4;granulocytes: 12.6;monocytes: 11.1" "Cell line enhanced" "Detected in many" "ASC diff: 53.3;MCF7: 30.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA006935, HPA067508" Enhanced Enhanced "Endoplasmic reticulum" Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA006935: AB_1080003, HPA067508: AB_2685857" "unprognostic (1.88e-1)" "unprognostic (2.66e-2)" "unprognostic (1.34e-1)" "unprognostic (3.57e-2)" "unprognostic (2.70e-2)" "unprognostic (4.85e-2)" "unprognostic (6.08e-2)" "unprognostic (3.18e-2)" "unprognostic (4.22e-2)" "unprognostic (3.39e-2)" "prognostic favorable (5.23e-4)" "unprognostic (4.67e-2)" "prognostic unfavorable (6.33e-4)" "unprognostic (1.95e-1)" "unprognostic (4.41e-1)" "unprognostic (2.59e-1)" "unprognostic (2.08e-1)" 18.9 5.0 4.1 3.3 4.1 2.5 17.7 3.3 5.7 8.3 4.6 8.8 2.4 6.3 37.7 6.1 9.8 5.7 8.3 4.0 4.1 11.1 20.4 19.0 4.7 4.2 5.6 9.2 8.0 9.2 9.9 6.4 3.9 7.1 5.0 0.6 5.1 8.0 3.1 12.3 7.7 5.8 3.6 8.6 19.3 12.2 3.9 2.3 9.4 3.7 2.8 7.4 9.5 4.0 2.6 0.5 3.1 1.5 53.3 10.8 0.8 0.5 3.9 1.2 1.0 1.8 1.8 1.1 1.6 2.4 0.6 9.3 3.0 1.5 0.7 0.4 1.4 1.5 2.8 1.9 6.7 1.4 5.8 5.5 6.6 0.3 1.4 1.1 7.0 0.3 0.8 1.4 0.3 30.8 0.3 8.1 3.4 12.2 1.4 8.6 0.6 0.9 1.5 0.9 2.7 1.7 0.6 9.6 3.0 4.1 3.9 5.5 0.0 1.5 2.8 3.3 0.1 2.4 2.4 0.3 2.5 5.7 1.2 9.5 10.7 12.6 2.1 8.8 1.3 0.6 0.6 2.1 7.4 0.7 0.2 0.6 0.9 2.5 11.1 1.0 0.2 3.4 4.1 4.1 3.3 5.7 4.0 4.1 4.2 5.6 3.9 3.6 3.9 4.0 47.3 19.2 51.8 6.5 5.5 11.7 12.6 9.0 8.0 0.9 4.4 11.3 4.6 34.3 10.1 3.7 0.0 27.2 20.7 4.2 0.0 4.3 0.6 5.1 12.1 42.4 4.2 0.4 2.6 7.3 13.0 20.3 16.8 7.9 25.4 1.8 106.1 30.6 33.2 1.7 2.6 23.7 6.1 31.7 39.8 3.2 19.0 21.3 23.2 1.9 44.6 2.0 35.0 0.5 1.6 3.1 42.3 14.3 7.9 3.4 2.5 3.6 6.6 1.0 6.6 3.4 15.7 1.7 2.9 5.5 7.7 8.8 13.0 5.2 10.7 7.0 SLC29A4 "ENT4, FLJ34923" ENSG00000164638 "Solute carrier family 29 member 4" Q7RTT9 7 5274369-5306912 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 43.3;choroid plexus: 55.5" "Group enriched" "Detected in many" 5 "Enteroendocrine cells: 103.2;Horizontal cells: 168.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 49.2;SH-SY5Y: 70.7;U-2 OS: 23.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052829 Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 40: NK-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "Microtubules, Cytokinetic bridge" "HPA052829: AB_2681967" "unprognostic (6.04e-2)" "unprognostic (1.22e-2)" "unprognostic (8.49e-5)" "unprognostic (2.53e-1)" "unprognostic (1.47e-3)" "unprognostic (4.24e-2)" "unprognostic (9.59e-3)" "unprognostic (2.05e-1)" "unprognostic (2.55e-2)" "unprognostic (5.73e-2)" "prognostic favorable (4.52e-4)" "unprognostic (2.06e-1)" "unprognostic (3.02e-2)" "unprognostic (3.24e-2)" "unprognostic (2.63e-2)" "unprognostic (1.29e-3)" "unprognostic (6.60e-2)" 43.3 8.2 13.2 0.7 16.2 0.6 13.3 16.0 20.0 4.9 55.5 3.1 4.6 5.4 5.0 1.1 4.0 1.6 3.7 26.3 28.5 7.9 9.2 0.9 0.2 23.2 26.1 2.2 15.4 1.7 3.6 0.6 23.6 5.8 1.8 4.1 1.3 0.7 2.6 3.0 5.5 1.8 17.2 1.6 6.5 2.6 30.0 0.3 9.7 0.4 0.1 2.4 2.0 7.4 0.0 21.7 12.6 49.2 0.6 0.2 2.4 1.8 0.1 1.6 0.9 12.3 0.4 0.0 2.4 1.9 8.1 0.3 4.8 0.4 0.5 0.1 2.8 0.2 0.7 18.3 3.8 0.2 3.0 1.5 16.2 0.3 0.9 2.9 1.5 4.5 3.6 0.1 1.2 10.8 2.0 0.9 16.0 1.5 1.3 8.3 2.1 1.9 3.2 0.5 8.4 70.7 1.3 4.4 0.9 10.7 5.5 5.9 0.7 17.3 23.4 1.6 0.5 1.1 0.0 0.1 2.2 0.7 8.0 0.8 0.3 0.2 0.2 0.1 0.4 0.2 0.1 0.2 0.1 0.4 0.2 0.2 1.3 1.6 0.1 0.3 0.1 0.1 13.2 16.2 16.0 20.0 26.3 28.5 23.2 26.1 23.6 17.2 30.0 7.4 0.5 3.2 0.5 8.8 0.0 0.1 0.2 0.1 0.0 6.9 0.7 0.6 2.5 0.0 0.2 0.0 16.7 0.3 0.2 6.3 0.0 5.3 0.1 3.3 3.0 0.6 103.2 0.0 2.4 0.2 0.4 2.2 2.0 0.7 0.0 25.7 0.0 1.0 0.4 168.2 14.3 4.4 0.0 0.3 0.7 0.7 0.3 0.3 0.0 0.0 0.1 4.8 0.0 4.0 0.6 1.4 0.5 0.4 0.1 2.3 0.8 0.2 1.4 1.6 0.0 0.5 2.2 0.4 4.2 0.1 0.3 0.3 0.3 1.7 1.0 0.2 SLC34A1 "NAPI-3, NPT2, NPTIIa, SLC11, SLC17A2" ENSG00000131183 "Solute carrier family 34 member 1" Q06495 5 177379235-177398848 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "kidney: 155.4" "Cell type enriched" "Detected in some" 14 "Proximal tubular cells: 143.2" "Cancer enriched" "Detected in single" 12 "renal cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "HEL: 2.4;U-937: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051255, HPA077175" Approved Approved "Nucleoplasm,Nuclear speckles,Plasma membrane,Mitotic spindle,Cytosol" Yes NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 36: HEL - Hemostasis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles, Plasma membrane" "Nucleoplasm, Mitotic spindle, Cytosol" "HPA051255: AB_2681409, HPA077175: " "unprognostic (1.17e-1)" "unprognostic (3.33e-3)" "unprognostic (1.49e-1)" "unprognostic (3.49e-2)" "unprognostic (1.56e-3)" "unprognostic (2.28e-1)" "unprognostic (4.50e-2)" "unprognostic (4.43e-3)" "unprognostic (1.91e-1)" "unprognostic (1.14e-1)" "unprognostic (5.95e-2)" "unprognostic (1.23e-3)" "unprognostic (1.38e-1)" "unprognostic (2.01e-1)" "unprognostic (1.28e-2)" "unprognostic (4.66e-2)" 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 155.4 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 7.3 0.0 0.0 0.2 0.0 9.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 143.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.6 0.0 0.0 0.1 SLFN13 FLJ31952 ENSG00000154760 "Schlafen family member 13" Q68D06 17 35435096-35448837 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.6;salivary gland: 32.5" "Cell type enhanced" "Detected in many" "dendritic cells: 56.3;Endometrial ciliated cells: 59.9;NK-cells: 60.8;Plasma cells: 38.2;Respiratory ciliated cells: 75.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "NK-cell: 5.3" "Group enriched" "Detected in many" 4 "granulocytes: 4.5;NK-cells: 5.3" "Cell line enhanced" "Detected in many" "EFO-21: 38.9;HL-60: 131.9;REH: 75.0;U-266/70: 63.2" "HPA022532, HPA023064" Uncertain Approved "Cytokinetic bridge" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Cytokinetic bridge" "HPA022532: AB_1856615, HPA023064: AB_1856616" "unprognostic (1.11e-1)" "prognostic favorable (3.82e-4)" "unprognostic (4.73e-2)" "unprognostic (6.12e-2)" "unprognostic (2.00e-1)" "unprognostic (5.74e-2)" "unprognostic (9.38e-3)" "unprognostic (1.32e-2)" "unprognostic (3.34e-1)" "unprognostic (3.55e-1)" "unprognostic (5.06e-3)" "unprognostic (2.33e-1)" "unprognostic (1.33e-1)" "unprognostic (3.71e-2)" "unprognostic (1.21e-1)" "unprognostic (1.15e-2)" "unprognostic (1.29e-1)" 3.1 0.9 1.5 9.1 1.1 25.6 9.9 1.2 0.9 6.2 5.7 5.8 8.5 4.8 2.9 3.5 16.9 6.6 1.8 1.0 1.2 2.6 2.1 6.4 10.5 1.3 1.4 1.1 3.2 14.5 0.5 1.9 1.2 2.1 6.5 0.1 32.5 4.2 0.7 2.3 4.5 4.2 1.0 13.7 11.3 0.6 1.2 10.0 7.9 0.8 11.6 2.5 1.5 1.7 0.2 7.0 13.7 0.1 0.4 1.4 0.2 1.7 0.5 6.7 10.6 0.0 0.1 0.0 38.9 1.3 0.3 11.7 1.4 4.9 7.6 3.9 2.2 37.2 6.5 0.1 0.6 131.9 1.0 0.4 0.6 3.6 0.1 0.0 2.2 0.4 0.1 36.8 0.2 0.1 0.9 28.4 6.8 0.0 0.0 75.0 0.5 3.8 11.6 34.1 0.0 0.0 0.0 6.2 0.3 0.9 9.8 20.9 0.3 0.1 2.0 10.1 0.5 63.2 9.5 0.2 0.2 20.9 1.0 3.7 0.2 4.5 1.2 0.3 1.0 0.9 0.5 0.6 0.2 0.9 0.4 0.3 0.8 5.3 0.1 0.1 0.5 0.4 1.5 1.1 1.2 0.9 1.0 1.2 1.3 1.4 1.2 1.0 1.2 1.7 6.2 0.0 3.7 0.0 7.3 1.0 3.1 4.7 5.7 0.2 14.5 9.1 0.8 27.1 12.5 5.5 0.0 0.8 56.3 2.1 1.9 1.2 0.1 59.9 3.6 3.4 3.0 19.1 0.1 0.4 0.4 1.6 8.2 11.7 3.8 3.8 1.8 0.6 1.6 0.0 0.1 4.5 12.2 1.0 1.7 0.0 0.9 3.2 0.0 2.8 1.8 0.2 60.8 0.0 0.1 1.3 0.6 0.4 38.2 1.0 0.5 1.3 75.4 0.2 0.0 0.4 3.8 0.2 0.6 6.7 1.1 0.0 16.6 3.3 4.2 1.4 SMC2 "CAP-E, hCAP-E, SMC2L1" ENSG00000136824 "Structural maintenance of chromosomes 2" O95347 9 104094260-104141419 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 25.7" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 114.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071309 Approved Supported Nucleoplasm,Nucleoli Yes No 26000 "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "HPA071309: AB_2686385" "unprognostic (1.51e-1)" "unprognostic (2.01e-3)" "unprognostic (2.26e-2)" "unprognostic (2.23e-2)" "unprognostic (3.04e-1)" "unprognostic (1.05e-1)" "unprognostic (5.57e-3)" "unprognostic (2.59e-3)" "unprognostic (1.47e-2)" "unprognostic (4.35e-1)" "unprognostic (1.24e-2)" "unprognostic (1.01e-1)" "unprognostic (5.56e-3)" "unprognostic (8.02e-3)" "unprognostic (1.65e-1)" "unprognostic (1.12e-1)" "unprognostic (1.32e-2)" 5.2 4.1 2.8 11.3 4.0 18.4 6.6 4.4 3.3 7.5 1.3 8.2 7.5 6.0 2.6 7.3 4.7 4.0 7.9 2.2 4.0 6.3 4.7 4.5 16.0 4.9 3.7 4.7 3.5 5.7 1.5 6.9 4.1 4.2 8.8 5.6 3.1 4.7 2.2 7.4 7.6 5.4 3.5 7.2 6.1 12.0 3.5 25.7 7.6 5.4 15.9 4.9 3.2 5.0 59.3 45.0 49.4 45.9 10.3 14.9 46.2 53.5 25.4 46.9 39.4 39.3 44.9 112.6 25.2 27.7 40.5 97.6 72.3 34.8 63.2 71.6 30.3 67.9 68.8 25.5 2.7 41.5 65.6 9.8 7.0 63.7 25.7 15.9 33.7 71.2 55.8 89.8 43.0 28.9 109.1 21.3 42.9 47.6 34.8 72.0 141.3 42.2 20.1 21.1 46.5 35.9 63.8 29.6 15.5 20.5 59.5 28.0 27.1 56.8 59.1 79.3 67.9 32.6 118.2 64.6 36.8 59.8 70.3 15.0 2.2 2.5 4.8 5.9 5.4 7.3 4.4 4.8 2.6 7.9 5.0 5.8 0.3 7.0 7.4 4.4 6.0 2.4 2.8 4.0 4.4 3.3 2.2 4.0 4.9 3.7 4.1 3.5 3.5 5.0 19.6 25.6 11.9 6.5 19.9 27.3 16.4 27.6 11.4 39.7 16.6 19.3 45.1 7.2 17.8 16.5 8.4 54.3 15.2 13.7 35.2 18.9 40.0 114.6 21.6 21.4 4.9 95.3 10.2 20.4 93.8 20.2 13.3 16.0 22.2 40.4 21.0 7.6 44.3 28.6 15.5 14.6 26.4 19.8 19.8 24.7 18.6 22.9 7.2 7.5 19.8 15.6 22.6 5.5 18.4 15.6 6.3 12.4 40.9 7.3 10.3 15.0 12.0 19.1 13.1 25.1 37.7 84.5 93.5 27.4 23.2 25.9 18.1 28.1 35.0 14.2 SMIM6 "C17orf110, ELN" ENSG00000259120 "Small integral membrane protein 6" P0DI80 17 75646243-75647975 "Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "fallopian tube: 24.1;kidney: 22.1;stomach 1: 33.1;testis: 26.1" "Cell type enhanced" "Detected in many" "Early spermatids: 565.7;Endometrial ciliated cells: 233.1;Enteroendocrine cells: 197.1;Late spermatids: 1243.9" "Cancer enhanced" "Detected in many" "endometrial cancer: 12.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 42 "plasmacytoid DC: 34.2" "Lineage enriched" "Detected in single" 42 "dendritic cells: 34.2" "Cell line enhanced" "Detected in some" "A549: 11.7;CACO-2: 3.8;EFO-21: 8.7;HEL: 6.7;Hep G2: 3.6;OE19: 10.5;RPTEC TERT1: 4.2" HPA065721 Uncertain Approved Nucleoplasm Yes NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 21: OE19 - Mitochondria" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA065721: AB_2685546" "unprognostic (4.34e-2)" "unprognostic (3.08e-2)" "unprognostic (7.07e-2)" "prognostic favorable (1.49e-4)" "unprognostic (3.42e-1)" "unprognostic (1.22e-2)" "unprognostic (6.53e-2)" "unprognostic (1.94e-1)" "unprognostic (1.13e-3)" "unprognostic (1.01e-1)" "unprognostic (3.76e-2)" "unprognostic (8.06e-2)" "prognostic favorable (4.09e-4)" "unprognostic (2.77e-1)" "unprognostic (1.38e-1)" "unprognostic (2.58e-2)" "prognostic favorable (1.64e-4)" 0.2 0.1 3.4 0.8 5.8 1.1 0.1 4.9 5.1 2.4 2.5 6.5 9.5 1.1 2.8 0.1 24.1 9.6 0.0 3.6 3.9 22.1 6.6 2.4 0.4 5.4 5.6 0.1 5.6 2.1 0.0 0.3 5.8 0.2 6.6 0.1 0.1 1.4 0.1 0.3 5.9 0.1 4.1 0.2 33.1 26.1 4.7 0.1 0.1 0.0 0.3 1.8 0.1 8.2 0.7 11.7 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.8 3.3 0.0 8.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 6.7 0.4 3.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.2 4.2 1.9 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.2 0.2 0.2 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 34.2 0.0 0.3 3.4 5.8 4.9 5.1 3.6 3.9 5.4 5.6 5.8 4.1 4.7 8.2 0.1 3.2 3.1 0.0 0.9 0.1 3.4 2.3 0.0 0.0 0.2 0.1 0.1 35.8 5.4 35.0 0.0 0.5 9.5 56.2 137.0 35.9 565.7 233.1 2.9 0.8 197.1 0.0 0.0 16.6 3.7 0.3 70.3 22.1 0.0 0.0 0.4 7.0 0.6 0.0 0.0 51.5 8.2 0.0 0.3 1243.9 6.5 1.4 0.0 0.0 1.6 0.0 0.0 0.0 4.5 55.8 129.5 1.9 0.5 2.6 32.7 24.5 38.4 0.0 6.6 0.2 0.4 5.2 2.6 0.0 0.0 4.1 0.9 0.0 4.4 9.6 SNPH bA314N13.5 ENSG00000101298 Syntaphilin O15079 20 1266280-1309328 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 75.5" "Cell type enhanced" "Detected in many" "Astrocytes: 45.7;Bipolar cells: 24.3;Excitatory neurons: 60.6;Horizontal cells: 30.3;Inhibitory neurons: 71.7;Oligodendrocyte precursor cells: 38.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.0;naive CD8 T-cell: 1.0" "Lineage enriched" "Detected in single" 9 "T-cells: 1.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049393 Approved Uncertain "Cytokinetic bridge,Mitochondria" Yes No "Cluster 32: T-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "Cytokinetic bridge" "HPA049393: AB_2680744" "unprognostic (1.43e-2)" "unprognostic (2.55e-2)" "unprognostic (2.28e-1)" "unprognostic (8.84e-3)" "unprognostic (2.06e-1)" "unprognostic (1.85e-1)" "unprognostic (2.56e-2)" "unprognostic (5.33e-2)" "unprognostic (3.08e-2)" "unprognostic (3.15e-2)" "prognostic favorable (6.97e-5)" "unprognostic (1.03e-1)" "unprognostic (6.94e-3)" "unprognostic (2.45e-2)" "unprognostic (1.55e-1)" "unprognostic (2.99e-1)" "unprognostic (1.21e-1)" 1.6 3.7 47.2 1.5 49.6 0.6 1.6 7.5 75.5 4.0 0.0 8.4 1.5 6.4 1.9 1.8 6.5 2.6 7.1 54.0 19.0 2.7 0.3 2.4 1.6 38.0 19.0 2.1 3.5 4.4 12.5 0.6 38.1 5.9 0.8 12.9 6.1 11.1 7.2 1.2 4.6 4.8 7.1 1.7 5.1 3.9 33.3 0.9 5.0 1.6 0.8 4.7 3.0 44.3 2.3 7.6 0.1 6.5 7.6 4.0 0.0 4.1 5.2 4.4 2.0 0.3 0.7 0.4 2.4 4.9 10.9 1.2 1.0 5.7 0.8 1.6 1.8 4.7 1.2 0.1 4.0 0.0 7.1 2.7 2.7 4.5 0.9 4.3 5.6 4.5 0.9 0.2 4.0 0.0 0.4 0.2 2.4 0.0 5.7 0.0 1.5 0.1 5.8 3.4 0.4 2.0 4.1 0.2 5.8 0.6 0.3 0.1 9.6 7.1 5.3 6.4 1.2 0.6 1.4 0.0 3.8 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.2 0.2 0.0 0.0 1.0 1.0 0.0 0.0 0.0 0.1 0.1 0.5 47.2 49.6 7.5 75.5 54.0 19.0 38.0 19.0 38.1 7.1 33.3 44.3 0.5 0.0 0.0 45.7 0.6 0.1 0.1 2.2 1.2 24.3 2.4 0.9 4.7 4.3 1.2 3.7 6.2 0.0 2.3 0.9 0.0 0.4 10.4 0.2 0.7 1.0 8.4 0.0 60.6 0.6 0.1 1.3 5.6 0.5 0.0 2.1 2.2 0.0 0.3 30.3 71.7 1.0 2.0 0.0 0.3 5.4 1.5 0.2 0.0 9.4 0.2 2.7 1.0 38.2 1.7 1.1 1.0 4.1 0.4 1.6 0.1 1.7 1.2 20.3 6.6 2.6 1.7 1.3 0.5 0.2 0.1 0.0 1.6 1.2 1.8 0.1 SNRNP25 "C16orf33, U11/U12-25K" ENSG00000161981 "Small nuclear ribonucleoprotein U11/U12 subunit 25" Q9BV90 16 53828-57669 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 131.6" "Cell type enhanced" "Detected in all" "Distal tubular cells: 156.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 219.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041183, HPA044248" Uncertain Supported "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA041183: AB_2677353, HPA044248: AB_2678873" "unprognostic (7.87e-2)" "prognostic favorable (1.95e-4)" "unprognostic (6.04e-2)" "unprognostic (5.03e-2)" "unprognostic (2.04e-1)" "unprognostic (5.99e-2)" "unprognostic (1.17e-1)" "unprognostic (4.27e-2)" "unprognostic (1.64e-1)" "unprognostic (8.99e-2)" "unprognostic (4.32e-3)" "unprognostic (1.60e-1)" "prognostic favorable (1.16e-5)" "unprognostic (1.51e-1)" "unprognostic (1.52e-1)" "unprognostic (1.45e-1)" "unprognostic (6.03e-3)" 15.2 29.3 80.7 20.6 81.4 32.7 16.1 95.2 98.3 14.0 74.4 27.2 12.9 15.9 16.3 20.1 16.0 10.4 85.3 81.7 81.0 25.0 39.2 10.8 32.6 86.3 82.7 19.8 19.7 24.6 30.7 8.7 87.0 19.8 17.5 12.4 22.9 13.8 131.6 10.9 16.5 15.1 81.8 19.0 27.6 11.0 88.0 22.5 17.7 84.5 31.2 17.2 11.9 80.1 50.1 111.2 60.7 70.8 21.2 24.9 29.5 41.4 26.5 90.7 76.1 150.4 47.5 157.3 48.3 34.2 48.6 50.4 111.8 76.2 69.2 57.3 87.8 91.6 155.3 152.9 22.4 168.9 103.9 32.1 27.0 80.8 22.4 19.6 49.6 93.5 139.2 36.5 52.2 236.5 89.5 70.0 72.8 88.4 54.5 141.9 64.6 186.9 48.6 34.7 66.2 42.9 93.4 119.8 20.7 59.0 77.5 80.8 39.3 40.0 49.6 51.8 67.2 37.6 96.9 248.2 21.3 89.5 62.3 15.1 25.5 93.3 14.9 40.3 17.9 74.3 15.1 17.9 49.6 75.1 15.9 16.3 17.2 22.5 35.9 219.7 26.1 23.2 80.7 81.4 95.2 98.3 81.7 81.0 86.3 82.7 87.0 81.8 88.0 80.1 16.5 12.8 14.3 6.8 53.4 18.6 27.2 39.5 14.8 17.9 48.1 51.9 113.0 18.6 29.3 33.1 4.2 54.6 62.3 30.9 156.5 41.6 3.0 27.3 23.8 18.9 44.0 58.5 9.9 51.4 63.3 29.3 30.1 36.9 4.5 62.3 16.4 67.5 114.5 11.8 9.8 34.5 69.2 26.4 59.8 6.5 21.5 36.2 62.2 5.6 94.3 89.0 32.0 4.5 6.5 31.0 44.8 29.7 65.9 31.5 24.0 87.6 53.2 14.5 6.6 29.4 35.7 33.7 44.8 35.8 21.9 26.1 22.4 105.0 53.5 27.7 SOX10 "DOM, WS2E, WS4" ENSG00000100146 "SRY-box transcription factor 10" P56693 22 37970686-37987422 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Deafness, Disease variant, Hirschsprung disease, Kallmann syndrome, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 194.9;salivary gland: 114.3" "Group enriched" "Detected in some" 14 "Breast glandular cells: 32.3;Breast myoepithelial cells: 47.8;Melanocytes: 35.6;Oligodendrocyte precursor cells: 61.3;Oligodendrocytes: 59.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 510 "SK-MEL-30: 313.9;WM-115: 432.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003171, HPA068898" Enhanced Supported Nucleoplasm Yes NA "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "CAB003171: AB_2195374, HPA068898: AB_2686054" 2.9 2.7 76.9 2.5 133.7 0.1 21.7 103.1 102.8 11.8 24.9 26.6 1.5 0.8 1.2 2.7 2.5 2.2 8.8 82.7 89.0 0.5 0.5 0.1 0.0 134.7 114.0 1.2 0.8 0.0 1.8 0.0 123.3 6.8 2.6 0.5 114.3 5.8 0.6 17.0 7.1 1.9 87.3 0.3 6.1 2.7 114.2 0.0 0.9 1.5 0.0 8.4 9.5 194.9 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 313.9 0.0 0.1 0.4 0.0 0.2 0.2 0.0 0.2 0.0 0.3 0.1 0.7 0.0 432.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 76.9 133.7 103.1 102.8 82.7 89.0 134.7 114.0 123.3 87.3 114.2 194.9 0.3 0.0 0.0 0.0 0.1 3.2 0.1 0.0 0.0 0.0 32.3 47.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.4 0.4 0.9 0.1 35.6 0.0 0.0 0.0 0.0 61.3 59.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.3 0.7 0.0 0.9 0.0 0.2 0.0 0.0 0.0 SOX15 "SOX20, SOX26, SOX27" ENSG00000129194 "SRY-box transcription factor 15" O60248 17 7588178-7590094 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 87.4;skin 1: 48.2" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 209.2;Basal squamous epithelial cells: 447.3;Squamous epithelial cells: 388.1;Suprabasal keratinocytes: 169.9" "Cancer enhanced" "Detected in many" "testis cancer: 67.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 6.7;non-classical monocyte: 10.6" "Lineage enriched" "Detected in many" 5 "monocytes: 10.6" "Group enriched" "Detected in many" 8 "A-431: 130.6;HaCaT: 142.1;HBEC3-KT: 57.8;hTCEpi: 56.6" "Not detected" "Not detected" "HPA067196, HPA074049" Enhanced Supported "Nucleoplasm,Nucleoli,Golgi apparatus,Vesicles" Yes NA "Cluster 51: Monocytes - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Nucleoli, Golgi apparatus, Vesicles" "HPA067196: AB_2685802, HPA074049: AB_2686656" "unprognostic (5.79e-3)" "unprognostic (6.65e-2)" "unprognostic (1.40e-2)" "unprognostic (2.58e-2)" "unprognostic (2.72e-1)" "unprognostic (1.60e-1)" "unprognostic (6.02e-2)" "unprognostic (2.81e-2)" "unprognostic (5.00e-2)" "unprognostic (8.50e-2)" "unprognostic (1.59e-1)" "unprognostic (1.24e-1)" "unprognostic (8.61e-3)" "unprognostic (1.03e-1)" "unprognostic (1.96e-1)" "unprognostic (2.95e-2)" "unprognostic (2.97e-1)" 2.2 0.9 15.0 0.8 14.6 2.7 3.4 17.4 23.3 21.1 11.8 12.4 0.7 8.2 1.7 87.4 11.0 1.0 8.6 14.5 15.3 1.7 1.3 1.5 0.5 14.3 15.0 15.3 1.0 0.2 7.9 0.3 14.1 12.1 0.5 5.0 14.6 7.1 2.3 48.2 3.5 1.3 14.5 1.1 4.7 2.6 14.7 1.0 2.3 1.8 2.8 10.4 32.7 15.0 130.6 3.2 1.8 1.0 0.1 0.3 9.6 1.4 0.5 1.1 1.7 2.5 0.8 0.4 1.2 0.1 0.4 142.1 0.1 57.8 0.4 3.3 3.9 0.5 1.7 0.5 0.2 0.3 2.6 0.0 56.6 0.7 11.9 3.6 0.0 2.6 2.9 0.8 0.2 0.9 0.6 1.5 3.6 0.3 0.7 1.6 1.8 1.0 2.7 0.7 0.8 2.2 1.5 0.5 0.7 5.5 1.1 1.0 1.6 1.3 2.3 1.6 4.4 0.9 1.5 1.6 4.4 1.7 3.2 0.1 2.1 0.0 0.0 6.7 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 10.6 1.0 0.0 0.4 15.0 14.6 17.4 23.3 14.5 15.3 14.3 15.0 14.1 14.5 14.7 15.0 0.8 0.0 0.0 2.6 0.1 209.2 51.8 72.7 447.3 13.6 6.3 13.0 4.7 0.0 20.6 1.8 14.6 1.7 0.7 0.5 1.9 0.1 0.2 0.4 4.9 3.1 1.2 0.0 8.1 0.5 2.0 10.4 0.0 0.4 0.0 1.3 1.4 0.0 0.4 10.1 7.7 0.4 10.2 1.2 19.3 1.1 31.4 0.9 26.6 1.0 1.2 50.0 0.0 4.0 2.4 0.5 0.1 36.9 4.9 21.2 0.3 0.2 16.2 9.4 32.9 7.8 7.1 0.7 10.9 388.1 169.9 1.1 1.1 0.6 0.8 73.8 SP6 "Epfn, KLF14" ENSG00000189120 "Sp6 transcription factor" Q3SY56 17 47844908-47855874 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 22.8;skin 1: 14.6" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 57.5;Syncytiotrophoblasts: 98.8" "Cancer enhanced" "Detected in many" "urothelial cancer: 11.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "BEWO: 92.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA024516, HPA044469" Supported "Nucleoplasm,Mitotic spindle,Centrosome" Yes No "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "Mitotic spindle, Centrosome" "HPA024516: AB_10960551, HPA044469: AB_10966430" "unprognostic (3.06e-2)" "unprognostic (4.32e-2)" "unprognostic (1.07e-2)" "unprognostic (7.55e-3)" "unprognostic (6.79e-2)" "unprognostic (4.57e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.11e-6)" "unprognostic (1.22e-1)" "unprognostic (8.72e-2)" "unprognostic (3.92e-3)" "unprognostic (1.63e-1)" "unprognostic (9.59e-3)" "prognostic favorable (6.39e-4)" "unprognostic (3.33e-1)" "unprognostic (9.93e-2)" "prognostic favorable (5.72e-4)" 0.9 0.9 0.1 0.6 0.1 0.0 3.9 0.4 0.1 1.3 0.1 1.4 1.6 0.3 3.9 5.5 1.1 0.1 0.3 0.1 0.2 1.0 0.0 3.1 0.6 0.7 0.4 0.9 0.4 6.2 0.2 22.8 1.0 1.8 0.7 0.1 0.9 10.2 0.1 14.6 4.7 0.3 0.5 0.8 0.3 0.2 0.2 1.1 1.1 0.1 1.9 2.7 3.9 0.1 6.8 0.8 0.0 0.0 0.0 0.0 92.3 0.4 0.4 1.8 0.4 20.1 1.9 0.0 0.6 0.0 1.3 2.8 0.1 3.4 0.5 0.2 0.7 0.1 1.5 0.6 0.1 0.0 0.0 0.1 1.8 0.0 1.8 0.2 0.2 0.2 4.7 0.1 0.1 1.8 0.0 0.1 0.0 8.2 1.6 0.0 0.0 0.2 0.5 11.9 2.9 0.1 0.1 11.9 0.0 16.8 4.8 0.0 6.3 0.4 2.6 0.0 0.5 0.8 0.0 0.1 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.1 0.1 0.2 0.7 0.4 1.0 0.5 0.2 0.1 1.3 0.0 0.0 1.0 0.2 0.1 2.6 4.6 4.0 0.0 6.0 6.1 0.5 0.0 0.8 1.8 0.0 57.5 0.3 5.2 0.0 0.7 0.1 0.4 0.1 2.7 1.8 0.0 0.2 0.8 3.9 0.7 0.0 0.7 0.0 0.2 0.7 0.1 4.1 0.0 0.2 2.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 3.2 0.0 0.1 3.8 13.4 0.0 1.0 0.0 0.0 0.0 0.2 0.3 0.6 1.1 0.9 98.8 0.3 0.1 3.3 6.3 SPAG5 "DEEPEST, hMAP126, MAP126" ENSG00000076382 "Sperm associated antigen 5" Q96R06 17 28577565-28599025 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.9;kidney: 37.8;testis: 74.0" "Cell type enhanced" "Detected in many" "Early spermatids: 126.0;Erythroid cells: 37.2;Spermatocytes: 72.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 11.7;T-reg: 4.9" "Group enriched" "Detected in many" 6 "granulocytes: 11.7;T-cells: 4.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA022008, HPA022479, HPA024418" Approved Supported "Nuclear bodies,Mitotic spindle,Cytosol" Yes Yes "Cluster 34: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies, Mitotic spindle" Cytosol "HPA022008: AB_1853519, HPA022479: AB_1853521, HPA024418: " "unprognostic (4.71e-2)" "unprognostic (1.32e-1)" "unprognostic (5.31e-3)" "unprognostic (2.32e-3)" "unprognostic (3.50e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (5.43e-5)" "unprognostic (3.37e-3)" "unprognostic (4.84e-3)" "unprognostic (5.97e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (3.49e-2)" "prognostic unfavorable (5.43e-13)" "unprognostic (2.64e-1)" "unprognostic (1.66e-1)" "unprognostic (2.90e-2)" "unprognostic (2.01e-1)" 2.2 3.3 7.8 7.8 7.6 37.9 2.4 5.8 9.1 2.6 3.4 8.3 7.9 1.9 2.4 8.3 1.7 1.8 1.4 7.6 7.7 37.8 14.8 3.4 14.5 6.7 6.8 2.7 1.5 1.1 4.3 5.7 6.7 2.2 10.7 10.8 2.4 0.8 1.0 5.5 9.1 3.4 5.0 7.4 3.6 74.0 7.7 22.4 8.7 0.7 17.3 2.6 3.6 7.5 84.7 87.7 103.3 78.4 5.2 8.6 42.4 65.9 42.4 98.1 78.3 69.2 25.5 59.8 34.2 46.8 91.7 70.2 114.5 42.7 103.8 108.6 72.9 62.9 87.9 80.2 0.6 83.1 76.1 2.9 3.8 78.6 40.4 14.5 52.1 90.6 69.7 101.5 80.7 52.6 109.4 92.9 54.2 68.3 44.5 72.1 144.4 70.9 29.0 43.0 78.6 45.8 96.4 114.9 31.6 84.9 82.2 70.6 25.7 56.4 91.3 46.6 114.6 46.7 72.9 87.3 37.8 60.6 91.8 11.7 0.0 0.0 0.4 0.4 0.7 0.6 1.2 0.9 0.1 1.4 1.1 0.9 0.2 0.8 0.3 0.3 4.9 0.9 7.8 7.6 5.8 9.1 7.6 7.7 6.7 6.8 6.7 5.0 7.7 7.5 0.5 3.2 1.7 0.7 3.3 2.0 0.9 1.3 1.2 5.0 1.1 1.0 0.7 0.0 1.9 0.0 0.0 9.0 1.3 4.7 1.9 0.5 126.0 6.0 1.1 1.5 13.1 37.2 5.2 0.4 12.2 2.6 5.1 1.8 1.3 12.6 3.3 6.3 6.5 3.3 6.0 4.6 4.1 2.7 4.0 25.2 0.9 6.1 0.0 1.9 0.9 0.7 0.0 2.0 1.7 0.4 4.7 0.0 13.1 0.8 8.1 12.5 7.7 3.9 6.6 2.0 2.2 72.6 21.0 5.2 1.0 3.8 2.8 0.9 5.1 1.1 SPON1 "f-spondin, KIAA0762" ENSG00000262655 "Spondin 1" Q9HCB6 11 13962723-14268133 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 101.4" "Cell type enhanced" "Detected in many" "Astrocytes: 399.9;Endometrial stromal cells: 78.9;Muller glia cells: 141.9" "Cancer enriched" "Detected in all" 5 "ovarian cancer: 199.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 3.3" "Lineage enriched" "Detected in single" 33 "T-cells: 3.3" "Group enriched" "Detected in some" 36 "EFO-21: 213.7;RPTEC TERT1: 604.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038584, HPA077546" Uncertain Approved "Nucleoplasm,Nucleoli,Actin filaments,Microtubule ends,Cytokinetic bridge" "Secreted to blood" Yes No 11500000 28000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoli, Microtubule ends" "Nucleoplasm, Actin filaments, Cytokinetic bridge" "HPA038584: AB_10697394, HPA077546: AB_2732351" "unprognostic (1.66e-1)" "unprognostic (1.03e-2)" "unprognostic (8.36e-2)" "unprognostic (8.72e-2)" "unprognostic (1.52e-1)" "unprognostic (3.76e-2)" "unprognostic (1.82e-1)" "unprognostic (8.20e-2)" "unprognostic (1.05e-1)" "unprognostic (5.93e-2)" "unprognostic (6.45e-2)" "unprognostic (1.07e-1)" "prognostic favorable (3.12e-4)" "unprognostic (7.22e-3)" "unprognostic (7.89e-2)" "unprognostic (4.65e-2)" "prognostic unfavorable (1.88e-4)" 54.2 16.9 25.8 18.6 33.7 0.1 19.5 26.3 22.3 43.8 7.8 31.8 31.6 36.5 15.2 17.3 63.1 101.4 30.6 28.2 28.3 12.2 2.0 49.2 1.6 25.6 33.6 23.9 4.6 0.8 10.0 41.3 26.4 16.9 46.6 63.8 7.0 8.8 0.8 8.8 28.4 46.9 14.9 8.3 28.8 2.5 34.0 1.7 5.2 1.6 1.2 51.5 12.5 21.8 0.1 0.1 0.4 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 9.8 0.2 0.2 213.7 0.0 0.2 0.4 0.0 0.0 0.0 0.3 1.9 0.0 0.1 0.1 0.0 0.0 0.1 11.4 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.1 2.7 0.0 0.1 1.7 0.0 0.1 604.1 0.1 0.1 0.2 0.0 0.0 0.0 4.1 0.0 0.1 2.6 0.2 0.7 0.5 0.3 0.3 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.3 0.0 0.6 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 25.8 33.7 26.3 22.3 28.2 28.3 25.6 33.6 26.4 14.9 34.0 21.8 0.2 0.0 2.3 399.9 13.5 0.0 17.3 0.0 1.2 13.5 2.0 5.5 1.9 5.7 0.0 0.0 2.1 3.4 4.8 38.9 3.9 4.3 1.5 36.1 78.9 2.5 16.7 0.0 17.0 2.0 4.2 41.2 0.5 61.5 2.5 1.8 2.5 0.2 1.9 1.7 16.8 24.0 0.0 0.3 0.0 1.3 4.4 1.0 0.0 11.2 0.5 141.9 20.6 62.4 1.6 6.8 20.6 30.1 0.9 9.0 18.4 2.1 0.7 26.8 6.6 5.8 7.0 0.4 0.8 0.6 0.0 4.9 7.8 1.1 40.9 9.4 SRA1 "SRA, STRAA1" ENSG00000213523 "Steroid receptor RNA activator 1" Q9HD15 5 140537340-140558252 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Activator, Receptor, Ribonucleoprotein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044598, HPA050153" Approved Supported "Nucleoplasm,Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Microtubules, Cytokinetic bridge, Cytosol" "HPA044598: AB_2679013, HPA050153: AB_2681033" "unprognostic (1.51e-1)" "unprognostic (1.04e-2)" "unprognostic (8.69e-2)" "prognostic favorable (8.01e-6)" "unprognostic (9.32e-2)" "unprognostic (2.56e-1)" "unprognostic (2.90e-1)" "unprognostic (2.43e-1)" "unprognostic (9.38e-2)" "unprognostic (7.41e-2)" "unprognostic (5.58e-3)" "unprognostic (2.61e-1)" "unprognostic (5.34e-2)" "unprognostic (3.10e-2)" "unprognostic (3.01e-2)" "unprognostic (3.71e-1)" "unprognostic (1.04e-1)" 12.2 34.0 8.7 7.7 9.0 9.6 9.7 15.8 12.3 10.0 9.2 12.5 5.1 8.2 6.0 9.3 9.4 5.6 12.0 9.9 9.3 12.4 25.8 15.0 6.3 8.4 8.2 14.9 7.5 4.7 22.2 5.8 8.8 12.5 4.7 7.2 14.8 6.2 14.5 9.4 11.9 5.4 8.6 17.6 14.0 22.6 8.9 5.6 12.9 2.5 5.2 9.4 8.8 9.2 9.7 22.7 11.8 12.3 5.6 7.6 16.4 16.1 9.1 10.3 10.8 41.8 5.9 8.2 11.7 6.2 5.5 6.4 2.1 12.0 4.1 12.7 13.9 7.2 25.0 16.1 12.0 13.1 9.4 14.7 6.1 5.5 2.8 9.1 4.7 13.8 7.4 12.1 6.9 29.5 10.7 20.4 3.6 5.2 18.0 11.7 10.0 7.9 5.4 11.3 8.3 9.8 9.4 8.5 11.6 4.1 10.5 14.7 7.5 9.7 5.1 8.5 13.2 15.1 10.9 8.6 12.0 16.8 6.5 16.1 26.0 20.3 10.7 23.8 9.9 15.8 10.2 10.4 25.2 14.0 8.2 9.4 43.0 13.6 23.6 15.2 19.5 26.8 8.7 9.0 15.8 12.3 9.9 9.3 8.4 8.2 8.8 8.6 8.9 9.2 43.3 6.4 49.4 13.4 46.7 52.4 68.5 126.1 38.7 23.6 57.8 48.9 71.7 57.2 86.4 33.1 8.4 103.7 56.9 87.8 113.5 102.7 104.6 59.5 33.4 39.8 38.4 35.1 15.5 148.2 117.9 48.6 64.7 43.1 68.4 21.8 42.1 69.7 93.1 15.2 17.2 71.6 107.8 61.2 71.5 150.0 25.1 82.0 67.6 7.5 90.4 59.5 42.2 9.0 11.5 186.0 78.7 29.7 113.7 82.9 83.7 131.0 84.1 23.7 26.3 26.7 76.1 77.2 30.7 62.3 45.9 179.0 47.4 66.8 49.2 142.6 SS18L2 KIAA-iso ENSG00000008324 "SS18 like 2" Q9UHA2 3 42581840-42596934 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047377 Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria Yes No "Cluster 13: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoli, Mitochondria" Nucleoplasm "HPA047377: AB_2680020" "unprognostic (4.09e-3)" "unprognostic (1.90e-3)" "unprognostic (1.54e-1)" "unprognostic (1.19e-1)" "unprognostic (2.36e-1)" "unprognostic (1.57e-1)" "unprognostic (1.64e-2)" "prognostic favorable (7.03e-4)" "unprognostic (6.55e-2)" "unprognostic (4.51e-2)" "unprognostic (2.62e-2)" "unprognostic (2.94e-2)" "unprognostic (1.09e-3)" "unprognostic (1.44e-1)" "unprognostic (1.09e-1)" "unprognostic (1.96e-1)" "unprognostic (2.24e-3)" 21.0 17.1 27.6 18.5 28.6 33.9 21.9 28.8 37.1 19.8 26.7 17.5 19.0 12.6 17.8 21.2 15.7 10.4 18.7 28.2 28.4 24.5 32.4 19.6 35.4 28.2 27.8 19.1 21.6 13.5 25.1 9.9 28.3 35.9 13.6 13.7 19.1 8.6 16.2 24.9 25.6 7.4 28.4 31.6 22.7 10.1 27.8 23.6 20.4 11.0 30.2 19.4 18.5 31.5 32.3 14.0 29.0 26.4 34.9 27.8 17.3 20.6 22.4 28.7 32.2 27.1 29.1 43.3 18.2 13.6 31.6 17.9 33.9 28.0 30.9 21.7 40.5 46.9 28.9 45.3 25.4 62.5 36.2 22.1 17.7 23.7 21.9 20.6 31.4 39.1 43.2 65.4 23.1 29.3 44.8 76.4 45.9 42.7 34.2 23.6 20.6 61.2 32.3 38.2 16.2 23.0 17.6 27.2 29.8 30.2 35.8 57.4 19.5 18.0 29.0 42.8 38.0 46.5 76.3 73.5 26.3 66.1 17.0 60.4 56.4 84.9 88.4 66.0 121.0 120.3 116.3 106.2 62.1 104.3 99.5 101.1 75.8 83.0 50.9 74.5 139.2 90.4 27.6 28.6 28.8 37.1 28.2 28.4 28.2 27.8 28.3 28.4 27.8 31.5 39.3 12.8 16.7 5.5 96.3 107.1 70.1 101.5 91.0 16.2 78.6 77.8 19.3 42.9 46.1 27.6 8.4 57.1 102.9 39.2 56.7 43.4 4.3 47.0 37.9 37.0 55.1 67.3 13.6 49.2 75.8 39.0 39.8 71.9 45.7 39.6 32.5 61.0 66.8 23.5 11.2 51.1 79.3 38.6 51.2 3.7 34.5 43.0 51.6 6.5 69.3 38.1 88.6 3.0 25.8 50.6 58.9 15.8 72.4 75.6 121.4 85.2 28.2 26.8 13.1 26.4 32.5 19.4 24.7 84.5 138.1 37.4 103.2 34.5 53.7 99.2 SSC5D "FLJ35258, S5D-SRCRB" ENSG00000179954 "Scavenger receptor cysteine rich family member with 5 domains" A1L4H1 19 55488404-55519099 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 39.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 19.3;Fibroblasts: 27.0;Leydig cells: 18.0;Peritubular cells: 15.8;Skeletal myocytes: 32.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 26.9;BJ: 22.7;fHDF/TERT166: 27.5;hTERT-RPE1: 23.2;U-87 MG: 27.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA042008, HPA053316" Approved Approved Nucleoplasm,Cytosol "Secreted in other tissues" Yes NA 88000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA042008: AB_10804124, HPA053316: " "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.78e-2)" "unprognostic (1.28e-2)" "unprognostic (4.55e-2)" "unprognostic (6.65e-2)" "unprognostic (3.68e-1)" "unprognostic (1.16e-1)" "unprognostic (2.85e-2)" "unprognostic (1.34e-3)" "unprognostic (1.40e-1)" "unprognostic (6.20e-3)" "prognostic unfavorable (4.26e-8)" "unprognostic (7.73e-3)" "unprognostic (1.51e-1)" "unprognostic (1.20e-2)" "unprognostic (2.21e-3)" 13.1 2.2 2.6 3.6 4.6 0.1 8.8 3.0 2.1 23.0 1.8 33.6 1.9 39.7 3.9 5.7 17.0 12.9 17.6 1.8 2.1 3.6 1.7 9.1 1.3 3.9 2.6 14.5 1.8 0.3 17.6 1.9 4.0 8.8 2.8 1.1 3.4 12.8 3.6 5.6 8.7 20.1 2.2 11.1 9.8 2.6 3.6 2.0 3.8 2.8 0.5 10.6 15.9 2.1 0.1 1.4 0.5 0.0 3.3 26.9 0.0 22.7 5.5 3.7 4.6 0.4 0.0 1.2 0.3 27.5 1.1 0.0 0.0 0.0 1.9 0.1 0.3 5.6 1.5 0.0 5.2 0.1 9.6 12.3 0.0 5.4 0.0 23.2 0.0 0.7 0.2 0.3 0.6 0.1 0.1 0.5 0.9 0.0 0.2 0.7 1.2 0.3 2.5 0.0 2.9 0.4 0.4 0.0 0.5 0.5 0.4 1.2 7.9 1.0 1.3 1.1 3.8 0.4 0.0 0.1 27.8 0.3 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 4.6 3.0 2.1 1.8 2.1 3.9 2.6 4.0 2.2 3.6 2.1 3.5 3.2 0.6 4.2 0.3 1.9 0.3 0.3 0.0 5.3 0.8 1.1 2.8 0.0 0.1 0.0 2.1 0.1 0.4 0.8 1.9 0.1 0.6 1.5 19.3 3.3 0.0 0.0 1.5 0.0 0.1 27.0 2.0 0.9 0.0 0.5 2.2 0.0 1.2 3.3 1.1 0.4 0.0 1.0 3.8 1.3 18.0 2.0 1.8 2.8 0.7 2.1 0.0 0.0 0.3 0.1 0.3 15.8 0.3 0.3 4.6 0.2 0.7 1.9 0.0 32.1 6.8 0.9 1.1 0.4 1.8 0.0 0.5 0.9 1.4 0.2 ST8SIA5 SIAT8E ENSG00000101638 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5" O15466 18 46667821-46759257 "Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 12.2;brain: 17.0;parathyroid gland: 6.2" "Group enriched" "Detected in some" 5 "Excitatory neurons: 106.1;Inhibitory neurons: 75.5;Oligodendrocyte precursor cells: 32.2" "Cancer enriched" "Detected in single" 8 "glioma: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "WM-115: 87.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043813, HPA046771" Approved Approved "Plasma membrane,Midbody" Yes NA 24000 "Cluster 6: Brain - Smell perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Midbody" "HPA043813: AB_2678683, HPA046771: AB_2679798" "unprognostic (3.19e-2)" "unprognostic (1.16e-1)" "unprognostic (2.47e-2)" "unprognostic (1.33e-4)" "unprognostic (2.99e-2)" "unprognostic (4.83e-2)" "unprognostic (1.90e-2)" "unprognostic (1.39e-2)" "unprognostic (1.35e-1)" "unprognostic (1.36e-1)" "unprognostic (1.57e-2)" "unprognostic (1.84e-2)" "unprognostic (6.55e-2)" "unprognostic (8.85e-2)" "unprognostic (1.18e-1)" "unprognostic (1.12e-1)" "unprognostic (1.79e-2)" 0.1 12.2 4.0 0.0 12.9 0.2 0.0 17.0 11.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.1 6.2 0.0 1.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 6.2 0.5 0.0 1.4 0.1 0.0 0.7 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 7.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 5.1 4.2 0.2 0.0 0.1 9.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 8.3 0.0 87.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.0 12.9 17.0 11.4 6.2 0.0 0.4 0.1 1.4 0.0 0.0 7.7 0.1 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.0 7.8 0.0 0.0 1.8 0.0 0.0 0.0 0.1 1.9 0.0 3.1 0.0 0.1 0.2 0.0 0.0 106.1 0.0 0.0 0.2 0.0 0.0 0.0 12.9 0.0 0.0 0.1 0.0 75.5 0.2 0.0 0.0 0.0 7.3 0.0 0.0 0.0 3.7 0.0 1.1 0.0 32.2 9.1 0.1 0.0 0.4 0.0 0.2 0.0 0.1 0.2 0.6 0.0 0.6 0.2 0.8 0.1 0.0 0.0 0.0 0.0 7.7 0.0 0.1 STK17A DRAK1 ENSG00000164543 "Serine/threonine kinase 17a" Q9UEE5 7 43582758-43650713 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 644.6;T-cells: 273.7;Urothelial cells: 326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018138, HPA037979" Uncertain Supported "Nuclear speckles,Plasma membrane" Yes No "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear speckles" "Plasma membrane" "HPA018138: AB_2669784, HPA037979: AB_10795247" "unprognostic (1.81e-3)" "unprognostic (1.08e-2)" "unprognostic (2.67e-1)" "unprognostic (5.41e-2)" "unprognostic (5.11e-2)" "unprognostic (3.35e-2)" "unprognostic (1.03e-2)" "unprognostic (9.15e-3)" "unprognostic (2.07e-1)" "unprognostic (6.34e-2)" "unprognostic (1.36e-2)" "unprognostic (6.61e-2)" "unprognostic (2.99e-3)" "unprognostic (3.76e-2)" "unprognostic (3.08e-1)" "unprognostic (1.97e-3)" "unprognostic (3.66e-1)" 6.7 8.1 3.9 7.9 4.2 4.8 5.2 6.9 4.9 4.0 4.0 6.4 3.2 3.5 1.2 7.2 3.9 5.3 10.8 4.0 4.1 6.3 4.6 9.4 14.4 3.4 4.4 6.2 9.1 0.8 4.2 3.2 3.6 4.3 2.4 5.5 5.8 2.1 9.9 4.6 11.5 3.3 3.6 12.6 9.5 9.0 4.3 9.0 3.8 2.5 13.5 5.6 5.0 3.1 5.8 8.2 9.0 5.3 7.8 8.3 1.9 12.3 15.1 6.6 5.9 7.5 3.1 7.9 20.2 15.3 17.8 8.5 3.6 17.4 10.4 16.9 7.0 9.3 8.2 8.4 4.9 21.1 5.6 6.4 26.4 8.2 8.6 36.4 12.6 11.0 16.7 15.1 9.6 3.6 18.2 8.0 17.3 4.1 18.3 8.4 6.9 14.2 15.6 6.7 6.9 11.2 8.1 8.5 6.1 13.6 6.5 10.8 16.9 20.7 8.3 14.3 17.2 13.3 11.2 13.5 18.4 14.0 31.7 0.5 0.0 2.7 2.0 0.0 1.5 2.4 2.0 3.2 0.1 2.2 3.0 3.0 1.6 4.9 0.1 0.4 1.3 0.9 3.9 4.2 6.9 4.9 4.0 4.1 3.4 4.4 3.6 3.6 4.3 3.1 44.2 121.8 33.1 29.0 237.8 181.9 644.6 64.5 99.6 2.9 17.7 37.8 28.7 7.2 69.8 20.2 10.4 54.8 222.3 54.4 33.2 153.0 47.0 129.1 17.4 35.2 7.2 54.1 9.5 95.4 23.3 39.1 78.0 88.3 38.8 17.7 17.9 9.6 16.9 0.0 5.6 34.3 38.7 20.3 65.9 14.7 5.9 60.9 35.6 34.7 42.1 7.9 221.4 39.2 3.7 89.4 73.0 2.6 81.2 192.6 23.8 13.2 42.4 26.3 6.6 39.4 51.3 75.8 36.1 42.3 136.1 66.8 273.7 27.0 18.0 326.1 STK26 "MASK, MST4" ENSG00000134602 "Serine/threonine kinase 26" Q9P289 X 132023302-132075943 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 70.0;epididymis: 56.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 55.2;dendritic cells: 42.7;NK-cells: 53.5;Syncytiotrophoblasts: 59.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 140.1;U-937: 144.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059921 Approved Uncertain "Nucleoplasm,Golgi apparatus,Centrosome,Cytosol" Yes No 360000 "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "Golgi apparatus, Centrosome, Cytosol" "HPA059921: AB_2684163" "unprognostic (6.53e-2)" "unprognostic (7.83e-2)" "unprognostic (1.77e-1)" "unprognostic (1.02e-3)" "unprognostic (4.42e-1)" "unprognostic (1.03e-2)" "prognostic unfavorable (6.82e-4)" "unprognostic (1.18e-1)" "unprognostic (1.93e-1)" "unprognostic (1.31e-1)" "unprognostic (1.42e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (6.87e-5)" "unprognostic (4.76e-2)" "unprognostic (1.83e-1)" "unprognostic (1.77e-1)" "unprognostic (2.88e-1)" 6.0 2.5 1.0 15.2 2.7 70.0 6.0 1.7 1.3 6.8 2.5 11.5 9.6 46.6 56.3 13.1 7.4 5.6 1.4 0.7 1.5 3.5 5.2 7.2 26.2 0.8 0.8 2.1 3.7 23.5 5.0 25.2 0.7 20.0 11.6 0.2 7.3 35.8 0.9 7.8 6.9 38.1 0.6 13.2 12.2 2.2 3.8 41.3 3.7 1.2 23.5 11.8 7.4 0.7 32.9 11.3 1.3 0.0 5.2 4.9 72.0 1.0 4.0 0.5 0.6 30.1 29.0 44.6 19.4 7.3 22.1 36.5 80.8 51.1 0.0 39.1 66.6 64.6 25.9 28.4 4.7 135.3 5.1 6.9 30.0 0.1 33.7 15.1 14.2 60.0 29.2 40.4 12.2 29.0 140.1 124.9 64.4 22.0 4.3 99.9 39.7 57.9 32.6 51.8 26.6 29.6 19.2 17.0 0.9 54.9 22.0 35.4 0.3 12.8 13.7 39.0 47.9 31.0 52.0 49.8 11.7 144.8 6.5 59.1 9.5 31.6 22.8 12.4 22.4 14.5 15.2 19.6 11.3 12.6 19.7 20.6 18.2 41.0 22.7 4.2 7.2 20.4 1.0 2.7 1.7 1.3 0.7 1.5 0.8 0.8 0.7 0.6 3.8 0.7 0.9 22.4 15.6 0.0 24.7 0.0 36.4 0.0 6.8 0.0 5.9 10.9 1.3 5.7 8.1 11.0 0.0 55.2 42.7 6.5 3.9 4.5 0.6 7.4 1.8 1.7 1.2 12.8 2.0 7.1 34.7 9.6 15.3 17.9 11.4 0.5 1.4 4.4 11.8 0.0 1.4 4.8 0.0 8.8 0.0 0.4 3.4 17.3 0.0 2.8 13.5 0.0 53.5 0.0 0.2 10.9 4.0 2.2 14.5 33.6 1.9 1.5 6.6 0.0 6.6 6.7 3.6 1.8 2.5 16.1 0.0 59.1 27.4 0.6 6.5 18.2 SUMF2 DKFZp566I1024 ENSG00000129103 "Sulfatase modifying factor 2" Q8NBJ7 7 56064002-56080670 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA024040, CAB025743, HPA074892" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" Yes No 750000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "CAB025743: , HPA024040: AB_1857651, HPA074892: " "unprognostic (2.93e-1)" "prognostic unfavorable (6.58e-6)" "unprognostic (2.42e-2)" "prognostic favorable (3.96e-4)" "unprognostic (3.87e-2)" "unprognostic (9.11e-3)" "unprognostic (1.69e-2)" "unprognostic (1.19e-1)" "unprognostic (1.41e-1)" "unprognostic (7.20e-2)" "unprognostic (1.92e-1)" "unprognostic (7.26e-2)" "unprognostic (1.74e-1)" "unprognostic (1.74e-2)" "unprognostic (2.64e-1)" "unprognostic (1.99e-3)" "prognostic unfavorable (7.71e-4)" 64.1 64.6 26.1 43.0 29.7 51.5 57.5 29.3 27.1 91.3 45.0 67.4 89.2 57.5 64.8 46.8 102.6 70.6 30.8 25.1 27.8 93.4 94.8 71.6 50.2 35.2 29.6 59.7 91.8 115.8 31.8 45.5 33.4 79.3 69.1 11.0 69.5 77.1 22.4 47.5 74.4 57.7 29.9 57.0 92.7 23.7 30.8 57.6 91.2 21.4 51.3 57.2 43.6 35.9 352.3 102.9 46.0 211.8 214.4 147.5 68.9 114.5 156.1 92.6 114.5 57.2 278.0 57.1 96.5 162.4 90.4 172.3 27.4 131.3 61.1 90.6 42.9 36.4 63.5 54.2 138.4 89.7 108.7 116.8 124.5 83.7 143.3 186.9 137.7 101.4 116.4 236.6 151.3 76.8 77.2 115.7 63.5 272.0 52.2 61.5 45.4 359.0 127.7 39.1 54.0 65.6 142.4 294.2 140.9 98.9 294.5 144.5 115.2 85.6 121.1 211.1 98.6 160.8 130.8 84.0 139.7 165.7 283.2 58.1 60.3 22.0 71.1 80.5 90.9 59.8 70.9 71.8 72.3 49.1 75.3 75.2 4.4 49.0 90.3 132.6 82.7 90.2 26.1 29.7 29.3 27.1 25.1 27.8 35.2 29.6 33.4 29.9 30.8 35.9 44.0 57.7 30.5 20.5 47.3 33.8 44.1 46.1 39.9 25.7 57.9 25.4 10.4 87.2 31.0 90.1 14.6 44.5 85.3 45.1 19.6 95.3 3.8 93.1 70.2 43.7 59.3 41.7 21.2 55.7 96.7 54.7 55.5 78.9 54.5 47.0 51.0 91.3 68.1 43.7 24.4 61.8 22.4 79.8 38.7 8.0 69.6 50.4 53.4 14.0 73.0 23.8 70.0 10.6 24.2 48.4 64.6 47.4 65.0 50.7 91.8 45.6 34.5 13.5 52.6 41.6 44.1 31.6 28.6 52.8 41.9 46.7 52.7 58.7 85.8 42.7 SURF6 "FLJ30322, RRP14" ENSG00000148296 "Surfeit 6" O75683 9 133328776-133336188 "Plasma proteins, Predicted intracellular proteins" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Theca cells: 91.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023608, HPA074622" Approved Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA023608: AB_1857671, HPA074622: AB_2686703" "unprognostic (5.27e-3)" "unprognostic (8.67e-3)" "unprognostic (5.41e-3)" "unprognostic (3.69e-2)" "unprognostic (2.61e-1)" "unprognostic (3.20e-1)" "unprognostic (1.26e-3)" "unprognostic (3.60e-2)" "unprognostic (1.18e-1)" "unprognostic (9.37e-2)" "unprognostic (6.18e-3)" "unprognostic (9.32e-3)" "prognostic favorable (7.31e-5)" "unprognostic (1.50e-2)" "unprognostic (1.86e-1)" "unprognostic (2.06e-1)" "unprognostic (2.66e-1)" 10.4 11.7 8.1 4.1 7.8 4.9 10.3 8.7 7.5 12.4 5.9 13.6 6.2 11.9 2.6 12.5 11.2 2.5 10.5 7.2 7.5 11.7 12.3 8.5 5.5 7.7 7.8 13.1 11.2 3.9 8.1 3.3 7.8 11.5 3.4 3.3 9.7 4.0 17.9 13.2 12.1 2.7 7.5 11.4 9.9 7.9 7.9 4.6 10.6 3.9 3.7 12.2 11.1 8.1 5.6 8.7 6.5 9.8 4.0 3.7 10.8 8.8 5.1 7.7 4.8 13.8 9.2 16.2 6.7 4.9 5.6 16.7 8.4 9.3 2.8 10.8 9.6 11.2 10.5 8.3 7.2 19.1 9.3 5.3 8.0 8.0 7.4 6.8 4.0 15.6 25.1 8.4 6.8 14.7 15.5 15.7 19.1 22.7 15.6 16.1 9.1 16.7 6.7 5.3 13.7 11.6 8.6 13.7 7.8 3.9 12.2 10.6 8.4 17.3 9.3 8.9 12.0 6.2 9.6 21.0 6.5 12.9 10.4 3.3 3.0 1.4 4.3 2.9 4.5 4.6 3.9 3.9 3.3 5.1 5.2 4.4 0.8 3.2 2.7 6.0 3.6 2.5 8.1 7.8 8.7 7.5 7.2 7.5 7.7 7.8 7.8 7.5 7.9 8.1 25.7 44.8 27.3 4.6 20.9 23.7 15.7 11.0 24.5 26.5 33.4 32.3 30.0 28.6 24.5 22.0 6.2 32.2 20.3 36.8 21.5 29.2 1.3 21.1 42.2 23.6 33.6 14.1 4.3 19.6 25.2 21.2 18.8 25.1 25.3 25.4 16.4 35.2 21.2 21.9 4.8 40.3 6.1 14.7 10.2 4.1 27.7 13.7 7.2 5.6 18.6 15.2 29.9 5.0 4.1 29.0 33.3 27.8 14.4 24.8 50.6 26.1 13.2 19.6 0.0 15.8 20.3 19.2 23.6 26.3 27.6 19.0 18.1 91.1 57.7 13.3 SUZ12 "CHET9, JJAZ1, KIAA0160" ENSG00000178691 "SUZ12 polycomb repressive complex 2 subunit" Q15022 17 31937007-32001038 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes, Disease variant, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057436 Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli, Nucleoli rim, Nuclear bodies" "HPA057436: AB_2683439" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (3.65e-3)" "unprognostic (1.23e-1)" "unprognostic (2.49e-1)" "unprognostic (7.31e-2)" "unprognostic (2.66e-3)" "unprognostic (8.05e-2)" "unprognostic (7.27e-2)" "unprognostic (3.06e-2)" "unprognostic (6.29e-2)" "unprognostic (8.70e-2)" "unprognostic (3.28e-2)" "unprognostic (2.25e-1)" "unprognostic (1.28e-1)" "unprognostic (5.91e-2)" "unprognostic (1.31e-1)" 12.3 11.8 6.3 18.8 6.3 45.4 15.0 11.1 8.5 11.6 6.8 14.9 16.0 15.2 12.0 14.0 11.0 12.0 10.3 5.4 5.8 16.4 18.1 12.6 33.0 5.4 5.9 11.4 11.5 19.8 6.6 18.7 5.6 13.3 16.4 26.5 10.5 12.2 8.1 13.0 15.3 14.7 5.2 18.4 15.2 27.4 6.1 38.5 18.3 11.0 30.0 15.6 9.0 7.1 46.5 40.4 37.2 42.9 21.1 26.8 38.2 44.2 38.8 53.0 63.7 30.9 25.5 100.7 33.2 27.7 45.4 40.1 56.0 25.5 85.7 35.8 54.0 69.9 32.9 22.3 24.8 111.5 68.7 18.7 28.1 53.1 40.4 32.1 33.1 47.3 68.8 135.6 46.2 16.2 133.3 64.4 21.3 32.4 24.4 78.5 95.3 81.9 31.1 44.6 47.5 37.1 71.3 22.7 43.3 25.8 66.0 91.5 24.7 41.9 38.0 50.8 69.3 73.5 98.4 122.5 30.7 67.4 38.7 0.6 0.7 1.6 1.4 1.1 1.1 2.4 1.6 1.6 0.6 1.8 1.5 2.1 1.6 1.8 0.7 1.9 1.8 0.4 6.3 6.3 11.1 8.5 5.4 5.8 5.4 5.9 5.6 5.2 6.1 7.1 44.5 41.7 45.8 43.1 50.1 58.5 50.2 21.8 31.9 77.6 54.2 36.8 32.3 27.1 32.6 35.0 108.4 61.5 65.2 24.0 17.6 28.3 16.2 52.8 55.8 45.1 29.4 93.6 71.6 21.9 53.1 35.1 31.1 54.2 15.8 41.4 38.2 42.3 32.9 62.2 69.5 31.8 10.2 42.1 58.2 13.9 26.8 47.3 24.9 45.0 73.1 45.7 38.1 75.4 71.3 27.8 15.4 25.6 66.2 62.8 21.5 26.6 29.6 80.9 13.1 47.2 38.4 121.7 128.9 48.6 71.7 69.5 52.5 52.8 35.6 66.7 SVBP "CCDC23, MGC45441" ENSG00000177868 "Small vasohibin binding protein" Q8N300 1 42807052-42817397 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 149.0;Erythroid cells: 135.4;Spermatocytes: 158.0;Spermatogonia: 153.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008507 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" "Secreted to blood" Yes No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear bodies, Cytosol" "HPA008507: AB_2072066" "prognostic favorable (6.33e-4)" "unprognostic (2.68e-2)" "unprognostic (2.91e-1)" "unprognostic (4.60e-2)" "unprognostic (2.05e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.18e-4)" "unprognostic (3.15e-2)" "unprognostic (3.35e-3)" "unprognostic (1.59e-2)" "unprognostic (6.73e-3)" "unprognostic (2.16e-1)" "unprognostic (5.37e-3)" "unprognostic (1.17e-3)" "unprognostic (7.07e-2)" "unprognostic (2.44e-3)" "unprognostic (2.31e-3)" 34.7 15.1 36.4 13.7 37.7 43.1 29.9 39.1 49.9 30.9 33.6 29.3 11.6 24.9 26.2 17.7 27.2 15.2 24.7 37.1 38.4 25.6 19.1 17.4 23.0 38.2 37.3 36.3 12.1 22.1 30.6 20.6 37.5 20.3 15.7 22.6 15.9 15.4 28.0 17.7 19.9 19.2 38.2 22.1 19.0 52.9 37.1 48.3 19.0 23.5 23.5 23.9 24.8 40.3 25.9 12.9 75.2 26.9 30.9 48.3 37.2 21.5 18.1 28.8 29.7 22.8 20.2 29.1 23.5 28.6 22.6 18.3 14.3 23.7 35.2 53.6 23.7 54.5 12.1 43.9 25.6 41.3 35.2 31.2 37.4 16.2 15.4 29.7 29.1 56.0 46.2 14.3 35.3 12.0 41.5 50.8 40.8 23.7 14.5 30.9 55.8 19.2 29.9 25.3 45.5 40.4 26.8 14.9 31.7 76.9 11.3 120.1 22.7 25.4 28.1 19.6 35.6 14.9 19.1 20.7 16.1 27.5 24.4 60.5 40.2 76.5 26.8 40.8 23.5 56.4 46.5 32.3 39.2 59.8 42.8 37.2 70.3 37.3 43.8 33.0 115.7 24.7 36.4 37.7 39.1 49.9 37.1 38.4 38.2 37.3 37.5 38.2 37.1 40.3 46.2 9.6 6.3 0.0 25.0 0.0 33.0 0.0 23.9 6.2 33.1 53.1 0.0 28.6 9.3 20.2 2.1 53.8 20.0 19.5 54.8 51.7 149.0 32.2 34.6 32.3 18.2 135.4 0.0 24.5 66.0 36.6 14.3 18.2 11.4 22.8 42.8 45.6 70.4 6.7 0.0 19.6 0.0 51.8 0.0 61.6 42.9 48.4 0.0 0.0 70.2 33.1 29.9 0.0 0.0 43.1 21.7 53.8 16.9 21.9 20.5 43.2 7.3 15.5 59.2 28.1 28.4 158.0 153.8 21.4 0.0 61.6 21.4 24.1 23.6 31.1 TACC3 "ERIC-1, ERIC1, maskin, Tacc4" ENSG00000013810 "Transforming acidic coiled-coil containing protein 3" Q9Y6A5 4 1712891-1745171 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 58.9;lymphoid tissue: 52.4;testis: 50.6" "Cell type enhanced" "Detected in many" "Early spermatids: 70.4;Hofbauer cells: 43.9;Late spermatids: 69.9;Spermatocytes: 94.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005781, HPA006050, CAB010111, HPA022039" Enhanced Enhanced "Vesicles,Mitotic spindle,Centriolar satellite,Cytosol" Yes Yes 11000 "Cluster 5: Granulocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Mitotic spindle, Centriolar satellite, Cytosol" Vesicles "CAB010111: AB_628323, HPA005781: AB_1857724, HPA006050: AB_2667505, HPA022039: AB_1857725" "unprognostic (2.95e-1)" "unprognostic (1.18e-1)" "unprognostic (7.71e-2)" "unprognostic (4.35e-2)" "unprognostic (6.58e-2)" "unprognostic (1.84e-2)" "prognostic unfavorable (3.30e-4)" "unprognostic (1.10e-3)" "unprognostic (4.61e-2)" "unprognostic (9.12e-2)" "unprognostic (2.91e-2)" "unprognostic (2.26e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.66e-2)" "unprognostic (2.09e-1)" "unprognostic (4.44e-3)" "unprognostic (9.75e-2)" 5.3 3.9 4.2 24.9 4.3 58.9 3.5 5.2 5.3 3.6 5.2 10.3 6.6 3.3 4.8 14.9 2.8 4.2 3.3 4.5 4.4 2.7 3.5 6.5 43.2 4.8 5.3 2.2 1.4 2.3 2.6 8.7 4.8 2.4 10.6 1.9 3.9 2.5 2.0 6.4 12.9 6.4 4.2 22.1 6.4 50.6 5.1 52.4 2.8 3.4 39.3 5.0 5.4 4.7 106.7 88.7 129.5 72.2 6.7 15.2 72.9 114.6 62.1 135.4 87.6 93.5 122.8 133.8 48.0 65.4 149.9 71.4 142.5 86.8 131.1 59.8 77.0 113.8 67.2 85.8 5.9 146.6 85.5 5.2 5.7 85.6 46.0 26.0 102.2 110.3 106.3 90.8 123.8 87.1 207.5 204.0 139.3 89.2 111.6 139.1 90.5 55.0 73.8 125.5 99.8 62.8 70.1 42.3 33.1 95.2 83.3 90.5 56.4 75.4 90.0 65.4 176.7 69.5 102.5 207.1 43.2 141.1 109.1 45.5 30.0 37.9 8.5 12.5 11.1 7.8 16.5 11.5 15.3 10.8 28.3 13.1 91.8 12.2 9.6 8.3 42.5 32.5 4.2 4.3 5.2 5.3 4.5 4.4 4.8 5.3 4.8 4.2 5.1 4.7 6.0 0.0 6.7 2.0 16.5 2.2 1.2 3.2 1.2 1.7 2.4 3.0 2.6 2.8 3.4 9.2 8.4 19.5 6.4 11.2 0.0 2.2 70.4 4.2 2.8 5.2 1.2 37.2 2.3 0.7 20.4 6.0 12.8 4.3 5.1 24.5 8.9 5.1 43.9 5.0 3.2 9.5 4.1 23.2 10.8 69.9 2.8 34.1 0.0 4.7 24.4 1.4 6.2 0.5 0.8 2.9 4.2 2.6 18.0 1.3 2.6 2.8 0.9 2.7 6.6 2.0 4.8 94.3 37.7 12.8 1.4 4.0 23.2 2.2 16.1 2.7 TAF1D "JOSD3, MGC5306, TAF(I)41" ENSG00000166012 "TATA-box binding protein associated factor, RNA polymerase I subunit D" Q9H5J8 11 93729948-93784391 "Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030703, HPA055935, HPA060385" Uncertain Supported "Nucleoplasm,Nucleoli,Mitotic spindle,Centriolar satellite" Yes No "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Nucleoli, Mitotic spindle, Centriolar satellite" "HPA030703: , HPA055935: AB_2682974, HPA060385: AB_2684271" "unprognostic (9.91e-3)" "unprognostic (4.38e-2)" "unprognostic (6.80e-2)" "unprognostic (1.71e-1)" "unprognostic (5.40e-3)" "unprognostic (6.46e-2)" "unprognostic (3.68e-3)" "unprognostic (9.70e-2)" "unprognostic (5.24e-3)" "unprognostic (3.55e-2)" "unprognostic (4.50e-3)" "unprognostic (1.09e-2)" "prognostic unfavorable (3.17e-7)" "unprognostic (1.95e-1)" "unprognostic (2.51e-1)" "unprognostic (2.34e-1)" "unprognostic (6.37e-2)" 10.0 9.3 2.5 18.2 3.0 16.4 12.6 5.0 6.7 7.7 1.2 9.5 13.7 14.1 9.0 9.5 7.7 15.4 7.1 2.9 3.5 6.8 6.9 8.1 20.6 2.3 0.6 13.8 20.9 5.3 4.9 18.0 2.3 9.9 12.5 8.2 10.1 7.3 8.0 11.4 13.3 9.1 0.5 11.9 11.9 5.5 1.7 10.9 10.1 7.1 13.1 13.8 7.2 7.8 18.2 8.6 17.5 17.9 14.0 47.8 29.2 27.0 11.5 18.4 13.8 28.6 38.8 32.6 34.0 15.6 12.6 44.3 21.5 25.9 21.2 10.6 7.8 34.8 55.6 20.2 16.4 31.9 25.1 19.5 25.8 16.0 35.7 35.0 23.7 22.7 24.2 50.4 22.8 5.0 25.8 66.4 12.1 16.7 9.6 23.3 19.1 30.9 22.7 17.4 10.7 19.5 10.8 38.2 16.5 19.3 32.7 12.4 28.7 26.9 30.5 44.2 28.7 22.9 26.2 32.5 11.2 36.9 10.3 44.2 16.7 28.8 17.3 12.5 17.7 39.1 24.9 19.8 12.0 39.8 28.4 24.1 42.7 18.1 10.8 26.1 18.2 5.2 2.5 3.0 5.0 6.7 2.9 3.5 2.3 0.6 2.3 0.5 1.7 7.8 106.7 89.8 95.5 20.9 246.1 244.2 252.4 66.6 255.0 86.6 129.4 130.9 26.2 134.4 105.3 29.5 39.6 176.0 162.5 94.5 45.0 95.2 19.9 144.9 184.9 121.3 110.2 98.4 41.6 146.3 170.2 147.1 125.4 245.6 104.4 257.2 63.1 54.2 69.3 69.0 38.2 148.0 24.4 103.7 153.6 16.5 128.6 112.0 80.0 24.4 102.1 34.8 89.6 35.2 44.0 110.4 87.5 67.7 162.2 269.2 71.1 101.5 67.7 78.2 72.3 187.4 123.1 49.0 71.5 251.4 203.0 160.9 182.3 119.7 174.1 356.8 TAL1 "bHLHa17, SCL, TCL5" ENSG00000162367 "TAL bHLH transcription factor 1, erythroid differentiation factor" P17542 1 47216290-47232220 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.4" "Cell type enriched" "Detected in some" 4 "Erythroid cells: 151.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 153.7;HMC-1: 70.6;HUVEC TERT2: 31.2;JURKAT: 60.0;K-562: 48.9;MOLT-4: 26.3;TIME: 34.4" "Region enriched" "Detected in many" 5 "midbrain: 14.3" "Low region specificity" "Detected in many" "CAB017805, HPA047866, HPA073983" Approved Enhanced Nucleoplasm Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "CAB017805: , HPA047866: AB_2680192, HPA073983: AB_2732246" "unprognostic (2.63e-1)" "unprognostic (2.62e-2)" "unprognostic (1.22e-1)" "unprognostic (2.40e-2)" "unprognostic (1.59e-1)" "unprognostic (8.80e-3)" "unprognostic (3.95e-3)" "unprognostic (1.33e-1)" "unprognostic (4.15e-2)" "unprognostic (1.99e-2)" "unprognostic (5.42e-3)" "unprognostic (3.68e-1)" "unprognostic (1.02e-2)" "unprognostic (2.76e-2)" "unprognostic (2.19e-1)" "unprognostic (1.51e-1)" "unprognostic (1.18e-2)" 7.5 2.5 4.9 1.0 4.5 29.4 6.3 4.7 4.4 2.9 3.0 2.1 0.8 2.9 0.6 1.8 3.5 2.3 5.9 4.6 4.6 4.4 1.5 13.0 1.4 6.5 7.1 1.2 0.9 0.9 1.7 6.9 6.8 2.1 1.3 0.2 1.1 0.8 2.1 1.7 3.1 2.7 6.9 7.1 1.8 0.9 6.4 0.4 5.4 2.5 0.7 2.4 2.5 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.2 0.1 153.7 0.0 0.0 0.0 0.0 70.6 0.0 0.0 0.0 0.0 0.0 31.2 60.0 48.9 0.1 0.0 0.0 26.3 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.1 34.4 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.5 4.9 4.5 4.7 4.4 4.6 4.6 6.5 7.1 6.8 6.9 6.4 6.8 23.9 0.0 0.0 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.1 0.1 3.7 1.5 1.3 1.8 0.0 0.1 0.0 0.0 0.0 0.1 5.3 0.0 0.1 18.1 0.0 151.5 0.0 0.0 0.3 0.6 0.0 0.0 36.8 0.0 26.7 0.1 10.6 0.0 0.1 0.0 0.0 1.6 1.5 18.2 0.0 4.8 1.8 29.0 0.8 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.4 1.3 0.4 0.1 1.0 0.0 2.0 0.0 0.0 0.0 TBC1D14 KIAA1322 ENSG00000132405 "TBC1 domain family member 14" Q9P2M4 4 6909242-7033118 "Plasma proteins, Predicted intracellular proteins" Autophagy "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 68.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 197.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036930, HPA067398" Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" Nucleoplasm "HPA036930: AB_10670155, HPA067398: AB_2685833" "unprognostic (3.05e-2)" "unprognostic (7.48e-3)" "unprognostic (4.80e-3)" "unprognostic (8.13e-2)" "unprognostic (2.83e-1)" "unprognostic (1.78e-3)" "unprognostic (9.63e-2)" "unprognostic (5.25e-2)" "unprognostic (9.71e-2)" "unprognostic (7.65e-2)" "unprognostic (1.80e-1)" "unprognostic (2.90e-1)" "prognostic favorable (5.28e-10)" "unprognostic (1.56e-1)" "unprognostic (3.50e-1)" "unprognostic (5.13e-3)" "unprognostic (4.12e-2)" 26.3 42.1 42.7 31.5 41.9 15.9 27.6 38.7 43.9 19.4 50.2 26.4 22.8 20.9 22.9 34.0 23.5 17.0 30.4 42.9 44.9 44.5 27.4 24.4 29.8 49.3 45.6 28.7 19.5 41.9 27.1 23.8 44.8 24.5 26.3 18.5 31.7 20.2 51.6 49.5 26.0 22.9 45.7 34.9 58.5 30.0 48.7 40.1 19.2 41.3 26.9 19.8 22.2 44.2 34.5 36.8 40.4 45.5 32.8 27.4 24.5 27.0 29.3 24.7 21.1 38.3 69.8 54.9 15.6 32.5 62.8 24.5 68.4 61.7 30.0 15.5 22.2 91.8 23.8 40.4 22.7 42.0 197.9 21.3 85.8 23.4 38.3 31.5 23.5 51.2 88.6 19.3 30.2 22.3 64.9 42.5 54.9 41.1 40.8 80.2 53.2 59.9 36.8 23.9 61.6 44.0 22.4 24.1 84.3 31.2 33.3 39.4 23.7 27.2 20.5 24.0 40.3 36.7 91.6 55.7 25.4 53.2 26.6 2.6 13.2 5.6 8.6 8.2 13.1 8.1 9.3 9.3 10.7 8.3 6.9 6.6 40.6 8.6 3.9 11.5 11.9 10.8 42.7 41.9 38.7 43.9 42.9 44.9 49.3 45.6 44.8 45.7 48.7 44.2 8.4 6.4 17.7 22.5 15.5 9.1 7.0 15.8 15.9 10.2 21.1 16.3 4.6 10.0 14.8 14.7 14.6 12.5 16.3 17.7 19.6 11.5 68.0 12.3 10.3 7.8 6.6 7.2 25.6 10.2 7.1 9.5 14.8 11.9 7.6 18.9 8.2 24.4 26.0 25.2 25.1 15.7 10.2 33.6 8.7 41.0 7.2 27.8 19.6 27.2 24.4 13.4 16.5 51.8 27.0 11.8 14.2 8.6 15.4 12.9 12.8 19.8 10.7 6.6 0.0 12.7 7.1 17.7 18.0 19.8 11.9 16.4 16.3 12.5 19.9 10.1 TCF7L2 "TCF-4, TCF4" ENSG00000148737 "Transcription factor 7 like 2" Q9NQB0 10 112950247-113167678 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "brain: 244.9" "Cell type enhanced" "Detected in many" "Astrocytes: 264.8;Distal enterocytes: 260.0;Extravillous trophoblasts: 231.4;Paneth cells: 211.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "thalamus: 244.9" "Group enriched" "Detected in many" 10 "intermediate monocyte: 28.9;non-classical monocyte: 86.6" "Lineage enriched" "Detected in many" 14 "monocytes: 86.6" "Low cell line specificity" "Detected in many" "Group enriched" "Detected in all" 9 "midbrain: 67.2;thalamus: 86.6" "Group enriched" "Detected in all" 5 "midbrain: 146.8;pons: 97.8;thalamus: 164.3" "CAB013535, HPA038800" Supported Approved "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 51: Monocytes - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nuclear bodies, Cytosol" "CAB013535: AB_2533167, HPA038800: " "unprognostic (1.79e-2)" "unprognostic (3.36e-1)" "unprognostic (1.11e-1)" "unprognostic (2.31e-2)" "unprognostic (4.59e-3)" "unprognostic (1.72e-1)" "unprognostic (2.09e-1)" "unprognostic (9.84e-2)" "unprognostic (5.09e-1)" "unprognostic (7.10e-2)" "unprognostic (6.10e-3)" "unprognostic (3.46e-2)" "unprognostic (7.25e-3)" "unprognostic (1.60e-1)" "unprognostic (1.55e-1)" "unprognostic (3.64e-1)" "unprognostic (7.36e-3)" 28.1 9.4 47.4 8.6 6.3 7.6 25.0 0.2 12.1 18.9 1.0 22.9 20.4 25.1 6.7 9.9 18.1 9.4 11.3 4.3 46.9 9.9 22.4 13.9 5.4 5.1 98.0 22.9 12.4 11.1 9.6 17.7 1.7 12.3 21.3 4.6 14.5 13.1 8.4 17.2 19.3 16.4 1.6 22.2 23.3 7.6 244.9 5.8 12.9 6.9 3.7 13.8 14.3 3.2 15.0 37.8 40.7 39.6 20.8 13.7 48.5 10.3 20.0 7.1 8.5 24.9 45.3 0.1 11.3 19.4 9.6 10.5 14.0 17.6 9.1 1.7 13.1 10.4 25.2 23.6 22.0 4.2 3.7 24.4 6.3 11.0 18.2 29.7 12.0 8.8 11.0 0.7 8.2 28.0 6.7 2.5 29.2 16.6 21.6 19.0 29.8 6.9 15.2 20.4 0.8 12.4 15.7 15.4 17.0 31.5 10.0 2.2 27.9 6.8 18.7 16.9 21.3 2.6 0.3 0.4 6.5 8.7 14.9 0.4 4.5 0.4 1.5 28.9 0.9 0.0 0.4 1.2 4.1 0.0 0.4 0.6 6.0 0.0 86.6 0.2 0.0 3.5 47.4 6.3 0.2 12.1 4.3 46.9 5.1 98.0 1.7 1.6 244.9 3.2 62.0 22.4 26.5 264.8 3.3 42.6 27.3 35.8 64.9 2.8 53.0 54.9 13.6 52.9 35.5 40.5 6.2 44.2 9.1 260.0 11.7 39.3 8.8 40.1 140.6 46.1 19.8 4.8 35.1 43.6 231.4 90.8 90.2 64.2 0.0 37.6 52.8 74.2 17.5 5.0 16.6 87.7 16.2 99.9 20.6 5.0 59.0 54.6 32.0 107.7 22.4 34.4 5.2 192.5 34.9 59.0 211.1 48.5 6.0 38.4 75.3 16.2 26.8 6.1 92.1 37.3 51.3 9.4 28.9 61.1 39.8 28.5 6.7 13.1 73.9 49.0 TDRD6 "bA446F17.4, CT41.2, NY-CO-45, SPATA36" ENSG00000180113 "Tudor domain containing 6" O60522 6 46687875-46704319 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 30.3" "Group enriched" "Detected in many" 4 "Early spermatids: 224.8;Spermatocytes: 82.7" "Cancer enhanced" "Detected in some" "prostate cancer: 2.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HeLa: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA075923, HPA077353" Enhanced Approved "Vesicles,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 21: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "Microtubules, Cytokinetic bridge, Mitotic spindle" Vesicles "HPA075923: , HPA077353: " "unprognostic (2.01e-1)" "unprognostic (7.41e-3)" "unprognostic (7.25e-3)" "unprognostic (3.88e-2)" "unprognostic (3.54e-1)" "unprognostic (4.10e-2)" "unprognostic (1.03e-1)" "unprognostic (4.32e-2)" "unprognostic (7.97e-2)" "unprognostic (2.50e-1)" "unprognostic (2.20e-3)" "unprognostic (2.20e-1)" "unprognostic (2.79e-1)" "unprognostic (2.86e-1)" "unprognostic (2.00e-1)" "unprognostic (2.16e-2)" "unprognostic (4.38e-3)" 0.7 1.7 3.3 3.0 5.1 0.2 0.8 7.8 5.4 1.2 1.8 1.0 0.7 0.9 3.4 0.6 0.8 2.2 1.6 4.1 2.6 2.1 2.5 0.7 4.0 3.9 3.2 1.1 1.1 0.4 3.0 1.6 4.1 2.0 0.3 8.9 1.3 0.6 2.3 3.5 0.7 0.4 2.7 2.5 0.8 30.3 3.7 0.0 5.6 0.1 0.1 1.1 0.8 4.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 5.1 7.8 5.4 4.1 2.6 3.9 3.2 4.1 2.7 3.7 4.0 0.8 9.6 0.5 3.9 0.0 0.5 0.4 0.1 1.2 11.3 0.4 0.8 3.4 0.0 3.8 7.3 6.2 0.0 0.0 0.0 1.9 0.3 224.8 1.0 2.2 1.2 4.2 0.0 13.6 0.2 0.0 1.0 0.0 0.7 0.0 0.4 0.7 3.0 0.1 5.0 14.7 0.3 0.0 0.3 0.0 33.8 4.1 0.5 3.6 6.5 0.0 1.1 0.0 14.6 17.8 0.1 0.0 4.5 0.0 0.6 0.4 0.4 0.2 7.5 13.1 3.0 0.5 82.7 34.7 0.0 1.6 0.0 0.0 1.4 0.5 0.2 TFAP2C "AP2-GAMMA, ERF1, hAP-2g, TFAP2G" ENSG00000087510 "Transcription factor AP-2 gamma" Q92754 20 56629306-56639283 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 29.1;skin 1: 53.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 132.4;Basal squamous epithelial cells: 120.1;Breast glandular cells: 66.1;Breast myoepithelial cells: 79.6;Cytotrophoblasts: 91.7;Extravillous trophoblasts: 59.7;Squamous epithelial cells: 81.0;Suprabasal keratinocytes: 149.3;Syncytiotrophoblasts: 105.6" "Cancer enhanced" "Detected in many" "testis cancer: 54.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "BEWO: 190.6;MCF7: 169.2;SK-BR-3: 308.9;T-47d: 86.8;WM-115: 114.7" "Region enriched" "Detected in single" 13 "olfactory bulb: 2.4" "Region enhanced" "Detected in single" "olfactory bulb: 1.4" "CAB016061, CAB016079, HPA055179, HPA057076" Enhanced Supported Nucleoplasm Yes NA "Cluster 31: Skin - Epidermis development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "CAB016061: AB_667770, CAB016079: AB_2199447, HPA055179: AB_2682729, HPA057076: AB_2683329" "unprognostic (1.74e-2)" "prognostic favorable (6.90e-4)" "unprognostic (2.24e-2)" "unprognostic (2.02e-2)" "unprognostic (1.52e-2)" "unprognostic (6.75e-2)" "unprognostic (2.54e-2)" "unprognostic (8.26e-2)" "unprognostic (2.97e-1)" "unprognostic (1.61e-1)" "unprognostic (3.14e-3)" "unprognostic (2.63e-1)" "unprognostic (9.04e-5)" "unprognostic (2.31e-1)" "unprognostic (1.85e-1)" "unprognostic (6.71e-2)" "unprognostic (3.28e-2)" 1.8 0.3 1.3 0.2 0.6 0.1 26.1 0.5 1.5 18.3 0.5 4.0 0.2 6.2 5.2 29.1 2.6 1.0 0.3 1.7 0.7 2.0 0.0 2.6 0.1 0.9 0.8 0.3 1.0 2.6 0.8 17.0 1.2 7.1 1.2 2.7 20.7 4.4 2.1 53.3 0.3 1.1 0.5 0.1 0.7 1.0 0.6 0.7 2.3 0.1 3.0 3.9 19.2 1.0 12.8 15.8 0.1 0.2 0.0 0.0 190.6 20.1 36.4 25.0 4.5 3.2 0.3 0.0 1.3 13.3 13.3 42.7 27.3 5.5 17.0 0.1 2.8 0.0 1.7 0.0 0.0 0.0 1.7 0.3 21.4 7.4 7.2 0.0 0.0 8.1 0.2 3.2 0.0 169.2 20.8 1.2 9.5 9.9 20.7 0.1 0.0 7.0 0.0 10.1 5.1 0.1 13.6 308.9 21.8 28.3 86.8 4.6 0.2 16.2 0.4 8.6 15.4 0.1 0.0 0.1 4.0 0.1 114.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.6 0.5 1.5 1.7 0.7 0.9 0.8 1.2 0.5 0.6 1.0 0.7 0.0 9.5 3.9 0.3 132.4 29.9 2.4 120.1 4.1 66.1 79.6 1.0 0.0 5.6 9.2 0.0 91.7 1.5 1.7 0.0 0.3 0.3 7.8 18.7 2.0 3.0 0.0 0.0 0.0 59.7 7.4 1.5 16.0 0.0 0.0 0.7 0.0 7.8 0.0 0.0 1.7 10.2 0.3 8.2 0.0 0.0 1.6 21.4 3.7 0.0 0.3 0.0 0.0 0.0 1.0 0.6 0.0 3.8 18.6 0.0 0.0 5.2 0.0 0.0 0.5 2.1 0.0 1.8 81.0 149.3 105.6 1.3 0.0 1.0 18.5 TFCP2L1 "CRTR1, LBP-9" ENSG00000115112 "Transcription factor CP2 like 1" Q9NZI6 2 121216587-121285202 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 49.1;salivary gland: 97.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 79.1;Distal enterocytes: 117.9;Glandular and luminal cells: 83.0;Ionocytes: 262.4" "Cancer enhanced" "Detected in many" "testis cancer: 21.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 18.2;HEL: 15.7;hTCEpi: 17.3;RPTEC TERT1: 42.4;RT4: 31.8;SCLC-21H: 13.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA029708 Uncertain Approved "Nucleoli fibrillar center,Mitochondria" Yes NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "Nucleoli fibrillar center" Mitochondria "HPA029708: AB_10602479" "unprognostic (8.85e-3)" "unprognostic (4.19e-1)" "unprognostic (1.06e-1)" "unprognostic (1.02e-2)" "unprognostic (1.48e-1)" "unprognostic (3.91e-2)" "unprognostic (1.32e-2)" "unprognostic (3.16e-1)" "unprognostic (3.25e-2)" "unprognostic (2.72e-3)" "unprognostic (1.20e-3)" "unprognostic (5.76e-2)" "prognostic favorable (7.72e-6)" "unprognostic (1.05e-1)" "unprognostic (2.39e-1)" "unprognostic (6.67e-3)" "unprognostic (2.01e-1)" 1.9 0.3 0.9 1.7 1.6 0.2 28.7 1.7 1.1 18.1 19.0 19.0 0.6 0.5 8.3 13.3 3.5 2.9 0.2 1.7 0.9 49.1 0.2 5.6 0.2 1.6 2.1 0.1 6.4 2.6 0.8 7.4 1.1 13.6 22.6 0.0 97.5 2.0 2.6 31.9 3.2 0.6 0.7 1.8 16.3 1.1 1.9 0.2 37.6 0.1 1.2 1.8 10.9 0.7 0.0 1.6 0.0 0.1 0.0 0.0 18.2 0.0 0.0 0.0 0.0 1.5 1.1 0.0 0.7 0.0 0.7 0.4 4.4 4.5 0.0 0.0 3.2 15.7 0.0 0.0 0.0 0.0 0.6 0.0 17.3 0.0 4.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 7.9 0.1 0.0 0.5 2.1 42.4 31.8 13.3 0.1 1.7 0.1 0.0 6.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.6 1.7 1.1 1.7 0.9 1.6 2.1 1.1 0.7 1.9 0.7 0.1 6.4 28.8 3.9 0.3 1.7 38.0 10.3 28.5 0.0 22.1 11.6 2.6 17.2 35.4 79.1 0.0 32.2 0.9 117.9 31.3 2.7 0.1 43.5 5.8 1.0 10.2 0.0 0.2 1.5 2.3 0.8 58.6 83.0 0.0 1.2 0.0 0.4 4.9 0.0 0.3 31.2 262.4 4.6 0.8 0.5 0.3 5.5 7.2 9.4 0.2 0.5 0.0 0.0 0.1 7.4 28.0 0.0 2.1 36.3 0.3 27.7 11.9 0.0 0.0 1.9 1.1 0.1 1.5 41.0 3.3 20.2 1.1 9.5 44.3 40.7 TFDP2 Dp-2 ENSG00000114126 "Transcription factor Dp-2" Q14188 3 141944428-142149544 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 169.7" "Cell type enhanced" "Detected in all" "Early spermatids: 986.1;Late spermatids: 397.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "JURKAT: 216.4;MOLT-4: 423.3;REH: 222.7;U-698: 366.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018396, HPA070399" Supported Supported "Nucleoplasm,Vesicles,Mitotic spindle" Yes No "Cluster 49: Eosinophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "Vesicles, Mitotic spindle" "CAB018396: AB_2287284, HPA070399: " "unprognostic (1.35e-2)" "prognostic favorable (6.32e-4)" "unprognostic (8.08e-3)" "unprognostic (2.90e-2)" "unprognostic (4.69e-2)" "unprognostic (1.18e-1)" "unprognostic (1.14e-3)" "unprognostic (2.60e-3)" "unprognostic (5.42e-2)" "unprognostic (1.46e-1)" "unprognostic (5.04e-2)" "unprognostic (2.04e-1)" "prognostic favorable (9.84e-4)" "unprognostic (6.04e-2)" "unprognostic (3.91e-2)" "unprognostic (2.45e-1)" "unprognostic (1.08e-1)" 18.8 15.1 7.8 9.2 8.9 50.3 18.9 21.2 12.7 12.1 8.2 14.8 22.7 15.3 15.9 13.7 14.7 19.4 26.0 9.0 7.0 29.5 17.3 11.8 10.5 12.5 10.6 23.3 12.4 16.7 13.0 28.4 12.4 19.4 14.0 13.2 12.3 13.7 28.5 11.9 21.3 14.4 7.4 9.5 12.4 69.9 8.2 169.7 21.6 21.3 10.6 11.2 10.2 10.0 32.8 14.7 61.6 49.4 20.3 21.9 134.0 16.3 18.8 25.5 40.2 19.2 32.2 115.8 73.7 18.7 44.6 19.5 15.8 31.2 35.8 46.9 28.5 140.4 21.5 26.0 19.6 43.1 47.8 20.6 22.8 27.8 26.9 23.5 18.3 216.4 53.5 6.8 44.3 25.4 423.3 16.1 49.6 17.2 20.0 222.7 42.2 27.0 29.4 16.5 26.9 25.0 54.5 19.5 29.0 45.3 46.7 21.9 12.0 24.2 21.9 19.8 20.7 20.7 20.5 366.5 19.4 11.4 11.6 69.3 4.0 48.0 28.0 6.9 10.9 14.7 12.8 14.9 9.8 18.7 18.6 22.2 4.4 37.4 10.0 33.7 12.8 12.5 7.8 8.9 21.2 12.7 9.0 7.0 12.5 10.6 12.4 7.4 8.2 10.0 29.7 32.1 30.6 64.0 24.2 25.1 52.1 30.4 43.3 33.0 45.1 36.8 87.6 45.8 30.7 47.8 33.3 235.4 98.5 23.1 93.9 36.8 986.1 63.9 51.1 26.8 38.6 171.9 194.6 26.4 125.2 44.0 15.8 35.8 33.5 84.8 27.8 39.8 27.8 37.0 166.7 27.1 40.7 13.5 15.4 397.5 77.0 27.0 5.4 51.5 14.9 26.1 128.8 61.9 116.6 27.2 25.7 75.2 25.2 36.3 87.5 98.4 43.1 34.5 26.3 96.7 38.6 75.4 75.6 31.3 20.0 99.2 42.9 72.4 42.0 36.0 TGM2 TGC ENSG00000198959 "Transglutaminase 2" P21980 20 38127385-38166578 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Acyltransferase, Hydrolase, Protease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 432.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 204.5;Cytotrophoblasts: 311.1;Ductal cells: 226.7;Endometrial stromal cells: 459.1;Hepatic stellate cells: 408.0;Hepatocytes: 205.7;Pancreatic endocrine cells: 326.5;Syncytiotrophoblasts: 374.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CAPAN-2: 1546.7;EFO-21: 505.5;hTERT-RPE1: 994.3;HUVEC TERT2: 695.3;TIME: 924.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002598, HPA021019, HPA029518" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" Yes No 1700000 "Cluster 43: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 36: Stromal cells - Cell proliferation" Cytosol "Plasma membrane" "CAB002598: , HPA021019: AB_1858247, HPA029518: AB_10603133" "unprognostic (7.80e-2)" "unprognostic (1.51e-1)" "unprognostic (5.22e-2)" "unprognostic (1.40e-2)" "unprognostic (1.56e-2)" "unprognostic (5.61e-3)" "unprognostic (2.81e-1)" "unprognostic (3.32e-3)" "unprognostic (3.29e-2)" "unprognostic (9.78e-3)" "prognostic unfavorable (2.97e-4)" "unprognostic (6.99e-2)" "prognostic unfavorable (1.67e-7)" "unprognostic (1.60e-2)" "unprognostic (1.93e-2)" "unprognostic (6.70e-2)" "unprognostic (6.40e-2)" 105.9 45.1 23.0 68.4 22.3 3.2 30.3 22.9 29.5 432.0 53.0 30.6 29.8 266.3 28.3 37.3 217.7 127.7 394.9 21.4 23.0 76.7 244.1 288.5 18.0 25.4 22.5 40.6 25.6 19.3 95.9 234.3 26.0 88.7 20.8 2.1 9.8 56.6 63.9 4.0 63.7 159.0 24.4 32.7 62.3 3.9 30.6 15.4 36.3 33.4 10.3 154.2 87.8 24.8 65.0 47.5 0.2 1.8 47.3 5.1 24.0 95.5 45.2 0.7 1.8 78.4 1546.7 0.1 505.5 1.0 105.4 1.7 0.1 221.7 3.4 0.7 0.2 10.3 2.6 35.0 191.9 0.0 0.5 5.2 0.4 40.2 0.3 994.3 695.3 0.0 21.4 0.1 16.0 0.3 0.0 0.6 0.8 0.9 4.6 0.0 0.1 0.3 69.0 0.0 0.0 1.3 224.4 0.2 7.6 31.6 2.2 0.6 924.2 1.6 57.6 7.8 46.3 0.0 0.6 0.8 60.7 0.1 18.4 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.0 22.3 22.9 29.5 21.4 23.0 25.4 22.5 26.0 24.4 30.6 24.8 58.0 9.6 18.3 0.0 7.4 0.5 10.4 41.0 0.6 0.0 8.5 8.8 204.5 31.5 55.3 14.7 2.1 311.1 0.1 11.7 3.9 226.7 3.2 16.7 459.1 183.8 0.0 74.5 0.1 145.7 38.6 37.7 0.5 13.1 2.5 2.8 408.0 205.7 54.4 0.0 0.1 1.8 6.1 23.7 2.1 5.0 1.2 35.5 0.0 28.1 6.5 0.4 0.0 0.0 0.3 326.5 1.1 6.0 0.0 68.6 63.0 27.6 23.6 0.5 0.0 5.2 49.1 0.4 4.0 0.9 0.0 374.2 3.9 2.1 3.3 26.4 THUMPD2 "C2orf8, MGC2454" ENSG00000138050 "THUMP domain containing 2" Q9BTF0 2 39736060-39779267 "Predicted intracellular proteins" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043042, HPA058025" Approved Uncertain Nucleoplasm Yes No "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA043042: AB_10964424, HPA058025: " "unprognostic (6.30e-2)" "unprognostic (9.12e-3)" "unprognostic (2.48e-2)" "unprognostic (4.62e-3)" "unprognostic (2.16e-1)" "unprognostic (1.39e-2)" "prognostic unfavorable (6.05e-4)" "unprognostic (1.22e-1)" "unprognostic (2.31e-2)" "unprognostic (1.30e-1)" "unprognostic (2.72e-1)" "unprognostic (2.54e-2)" "prognostic unfavorable (7.27e-5)" "unprognostic (2.17e-1)" "unprognostic (1.61e-1)" "unprognostic (1.49e-1)" "unprognostic (1.14e-3)" 2.4 2.0 2.6 0.5 2.5 1.7 2.1 2.9 3.0 1.9 2.6 1.9 0.5 1.7 0.2 3.5 1.5 0.5 3.3 2.6 2.6 2.4 2.3 2.2 1.4 2.6 2.8 3.2 2.2 0.5 2.3 0.4 2.6 2.0 0.7 0.4 2.1 0.4 6.0 2.5 2.0 0.4 2.4 2.5 2.2 0.9 2.6 2.0 2.1 4.0 1.5 2.1 2.4 2.8 4.9 4.7 1.0 6.5 2.3 3.3 2.7 1.3 2.5 3.0 3.1 5.0 4.5 7.8 2.7 1.6 7.6 2.0 9.7 4.4 3.2 13.1 10.8 4.7 3.0 5.7 4.1 6.3 2.4 3.9 3.2 3.1 1.0 2.9 4.9 1.5 5.9 1.8 6.1 2.3 3.3 5.0 0.0 13.0 2.9 3.4 4.2 5.4 2.9 2.6 5.7 3.1 1.3 5.6 3.2 0.4 1.8 3.9 2.5 4.0 2.5 1.1 3.6 2.4 3.1 5.1 2.0 11.4 3.2 0.0 0.6 0.0 0.1 0.4 0.6 0.7 0.4 0.1 0.5 0.3 0.6 0.4 0.1 0.4 0.1 0.9 0.1 0.6 2.6 2.5 2.9 3.0 2.6 2.6 2.6 2.8 2.6 2.4 2.6 2.8 17.4 25.6 20.6 26.8 17.8 14.3 29.0 19.5 15.9 26.8 14.4 29.8 23.7 8.6 20.3 14.7 18.8 11.5 23.0 7.2 19.6 16.6 4.5 7.5 16.9 13.7 9.6 23.8 42.2 13.7 13.6 18.4 17.9 10.9 7.0 19.2 10.0 9.9 11.3 6.7 41.6 8.1 8.2 10.9 7.7 4.0 28.0 10.0 5.4 45.0 11.8 12.1 15.5 45.2 30.3 16.7 17.1 25.6 8.2 23.7 10.3 16.4 10.9 21.1 6.6 20.5 16.0 9.1 19.7 16.9 13.5 6.8 12.6 22.2 13.5 22.7 TIAM1 ENSG00000156299 "TIAM Rac1 associated GEF 1" Q13009 21 31118416-31559977 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 207.9" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 327.3;Microglial cells: 133.0;Oligodendrocyte precursor cells: 120.6;Oligodendrocytes: 124.6;Suprabasal keratinocytes: 143.3" "Cancer enhanced" "Detected in many" "testis cancer: 15.1" "Region enriched" "Detected in all" 4 "cerebellum: 207.9" "Group enriched" "Detected in many" 5 "classical monocyte: 17.4;intermediate monocyte: 15.3;memory CD4 T-cell: 12.5;myeloid DC: 9.6;naive CD4 T-cell: 16.2;NK-cell: 11.3;non-classical monocyte: 22.0;T-reg: 27.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 34.5;HEL: 34.7;HMC-1: 29.1;RT4: 35.5;SCLC-21H: 32.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 245.9" "CAB010416, HPA034853" Enhanced Supported "Nucleoplasm,Nuclear membrane,Cell Junctions,Cytokinetic bridge,Cytosol" Yes NA "Cluster 27: Non-specific - Gene expression" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cell Junctions" "Nuclear membrane, Cytokinetic bridge, Cytosol" "CAB010416: AB_2240410, HPA034853: " "unprognostic (9.59e-2)" "unprognostic (7.44e-3)" "unprognostic (5.64e-3)" "unprognostic (1.07e-1)" "unprognostic (1.58e-1)" "unprognostic (2.81e-3)" "unprognostic (2.84e-2)" "unprognostic (3.73e-1)" "unprognostic (8.08e-2)" "unprognostic (2.70e-3)" "unprognostic (7.97e-3)" "unprognostic (9.52e-2)" "unprognostic (1.20e-3)" "unprognostic (2.38e-3)" "unprognostic (1.61e-1)" "unprognostic (1.04e-2)" "unprognostic (2.21e-1)" 7.2 12.7 40.3 6.6 35.2 2.8 5.4 207.9 49.2 17.8 12.5 5.1 1.7 9.9 3.2 39.7 11.0 4.6 5.5 51.8 26.5 5.5 7.9 5.8 11.1 26.7 33.4 3.3 2.2 0.3 12.9 4.3 36.1 9.0 3.1 8.6 5.6 3.3 0.9 27.2 5.0 11.1 27.5 5.2 2.4 10.5 37.3 18.7 1.9 0.8 11.1 12.1 18.5 28.6 2.9 1.0 21.7 1.3 0.4 4.9 34.5 0.0 0.0 2.7 0.9 0.2 3.9 7.6 1.5 0.5 4.0 5.1 2.5 4.4 4.3 0.6 12.0 34.7 0.7 0.2 0.5 0.0 29.1 2.2 1.5 14.7 5.9 2.6 0.0 11.3 0.0 10.9 11.1 14.7 5.4 0.2 7.1 5.3 9.4 7.0 6.8 0.0 3.3 35.5 32.6 8.1 1.5 11.4 1.3 7.5 4.7 0.1 0.2 3.1 12.5 0.0 1.5 12.3 9.9 6.6 7.2 2.6 24.2 1.5 17.4 0.0 0.5 15.3 3.1 0.1 12.5 2.4 9.6 0.0 16.2 1.0 1.0 11.3 22.0 0.5 27.8 5.9 40.3 35.2 207.9 49.2 51.8 26.5 26.7 33.4 36.1 27.5 37.3 28.6 3.7 3.2 2.3 21.2 1.7 83.7 65.6 3.0 22.8 8.9 4.9 1.9 1.1 1.5 11.8 0.0 2.1 10.1 8.0 1.3 0.0 1.8 11.7 25.2 2.2 31.4 5.4 2.7 43.9 0.7 29.7 11.4 2.0 28.4 24.1 2.0 35.0 5.5 8.1 74.0 327.3 0.4 10.2 22.9 73.4 11.3 34.5 26.3 10.6 133.0 37.3 35.2 4.1 120.6 124.6 1.8 11.6 58.3 3.2 30.8 0.0 0.5 1.2 4.6 6.6 0.9 2.1 1.3 9.8 60.2 143.3 10.7 16.3 82.6 1.2 106.7 TIGD1 EEYORE ENSG00000221944 "Tigger transposable element derived 1" Q96MW7 2 232543883-232550557 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041717 Approved Approved "Nucleoplasm,Nucleoli rim,Nuclear bodies,Mitotic chromosome" Yes No "Cluster 32: T-cells - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 24: NB-4 - Immune response" "Cluster 52: Non-specific - Transcription" "Nucleoli rim, Mitotic chromosome" "Nucleoplasm, Nuclear bodies" "HPA041717: AB_2677636" "unprognostic (2.48e-1)" "unprognostic (1.77e-2)" "unprognostic (2.10e-2)" "unprognostic (1.86e-1)" "unprognostic (2.58e-2)" "unprognostic (2.81e-1)" "unprognostic (1.62e-2)" "unprognostic (1.24e-1)" "unprognostic (1.21e-2)" "unprognostic (1.20e-2)" "unprognostic (4.40e-2)" "unprognostic (6.86e-2)" "prognostic unfavorable (4.41e-5)" "unprognostic (3.77e-2)" "unprognostic (1.85e-2)" "unprognostic (2.77e-1)" "unprognostic (3.21e-3)" 1.8 2.3 6.3 2.3 5.3 6.5 2.7 13.4 7.8 3.2 5.4 2.8 1.9 2.6 2.9 2.8 3.8 1.9 2.4 5.0 4.5 7.4 2.7 2.5 3.4 3.2 2.4 5.7 2.9 1.6 5.0 2.0 4.1 4.4 2.1 10.4 2.7 1.7 4.0 4.2 3.6 1.3 1.5 6.1 3.3 5.2 4.5 3.3 4.7 1.4 2.2 2.8 3.0 9.7 3.1 2.3 4.7 7.5 1.7 2.3 3.6 2.1 1.2 2.6 2.9 2.8 3.6 5.0 1.5 1.6 2.8 3.2 4.1 1.3 3.8 3.0 3.9 4.5 7.7 3.5 1.1 3.6 2.9 2.6 1.2 2.6 1.6 2.5 1.5 6.5 3.6 5.0 2.1 5.3 4.9 8.3 2.8 1.9 2.7 4.7 6.3 2.3 1.5 3.5 6.1 6.0 2.2 2.1 2.3 3.3 3.1 3.9 2.5 4.3 4.5 2.7 2.1 4.8 3.4 4.5 2.5 3.6 2.6 1.6 1.7 1.8 1.9 1.4 1.9 1.7 2.0 1.5 1.1 2.1 3.1 2.5 2.3 1.8 1.5 1.2 1.6 0.7 6.3 5.3 13.4 7.8 5.0 4.5 3.2 2.4 4.1 1.5 4.5 9.7 2.4 9.6 3.9 4.2 5.3 1.3 4.5 2.3 1.8 4.9 2.5 2.2 2.0 1.5 2.9 3.7 8.4 2.2 3.1 1.7 0.0 3.6 4.2 1.0 3.6 1.7 1.2 6.5 4.5 1.5 1.3 3.1 7.7 1.5 0.0 6.4 1.4 0.7 1.4 6.7 5.7 1.5 2.0 1.6 1.7 0.7 4.7 2.4 1.8 1.0 2.8 7.5 5.2 5.0 8.1 2.0 2.4 1.9 5.6 2.6 3.5 1.4 1.7 7.0 6.6 3.7 2.0 3.9 5.7 3.7 2.0 1.4 4.1 4.0 3.0 2.9 TIRAP "Mal, wyatt" ENSG00000150455 "TIR domain containing adaptor protein" P58753 11 126283065-126298845 "Predicted intracellular proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054431 Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 41: Basophils - Cellular respiration" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Cytokinetic bridge, Cytosol" "HPA054431: AB_2682486" "unprognostic (9.30e-3)" "unprognostic (7.39e-2)" "unprognostic (1.21e-1)" "prognostic favorable (1.24e-4)" "unprognostic (2.73e-2)" "unprognostic (5.77e-2)" "unprognostic (1.27e-1)" "unprognostic (6.89e-2)" "unprognostic (2.40e-1)" "unprognostic (2.28e-1)" "unprognostic (4.65e-2)" "unprognostic (1.42e-1)" "unprognostic (3.34e-3)" "unprognostic (4.29e-3)" "unprognostic (3.62e-2)" "unprognostic (3.47e-1)" "unprognostic (2.57e-1)" 4.3 4.3 1.5 4.9 1.4 2.9 4.5 3.1 2.4 5.4 3.6 5.3 7.6 4.5 2.5 4.4 5.3 4.5 5.3 1.3 2.1 3.9 6.3 4.2 4.1 1.9 1.8 8.0 4.7 7.2 3.6 4.9 2.1 5.7 5.5 3.1 8.0 6.4 5.3 4.3 6.9 4.7 1.0 5.0 4.3 1.5 1.6 3.1 4.8 4.9 5.1 4.5 3.3 1.1 2.2 7.0 3.7 6.2 6.2 8.5 4.4 5.7 9.3 3.9 3.7 11.0 8.3 5.7 9.6 5.9 6.9 6.2 3.9 4.4 1.5 15.3 3.7 15.4 4.2 7.1 4.9 9.6 7.9 6.4 6.0 7.4 5.1 4.7 6.5 4.6 4.2 12.9 4.6 4.0 0.3 1.5 1.7 15.9 6.3 2.0 1.0 5.4 3.1 7.8 4.6 5.8 6.8 6.7 4.6 4.8 18.2 4.9 6.5 2.2 2.1 4.5 4.3 3.6 5.6 4.2 3.4 7.5 7.0 5.3 5.8 2.9 4.0 4.5 3.7 2.1 3.1 4.2 4.6 3.8 2.5 2.4 4.9 2.6 3.2 3.2 3.5 3.7 1.5 1.4 3.1 2.4 1.3 2.1 1.9 1.8 2.1 1.0 1.6 1.1 1.7 6.4 2.6 2.3 3.7 0.4 1.8 2.0 4.0 3.5 2.7 2.0 1.3 2.8 2.8 3.7 0.0 3.4 2.2 4.2 0.0 3.3 0.0 1.1 2.3 3.2 1.2 0.8 3.7 4.0 4.9 2.7 2.0 1.7 1.3 2.0 2.5 4.8 5.2 3.3 5.0 3.9 2.0 4.4 0.8 0.3 4.7 3.7 1.8 3.7 2.1 3.6 4.1 3.0 1.8 3.6 8.1 4.5 9.2 2.0 6.5 2.2 1.6 2.5 0.0 2.0 2.5 0.1 0.6 3.5 0.1 2.6 4.2 2.3 2.4 1.5 TM2D3 "BLP2, FLJ22604" ENSG00000184277 "TM2 domain containing 3" Q9BRN9 15 101621444-101652391 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054064 Uncertain Approved Nucleoplasm,Cytosol Yes No "Cluster 5: Granulocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm Cytosol "HPA054064: AB_2682366" "unprognostic (1.41e-1)" "unprognostic (8.76e-2)" "unprognostic (2.06e-2)" "unprognostic (2.55e-3)" "unprognostic (1.15e-1)" "unprognostic (8.37e-2)" "unprognostic (2.29e-1)" "unprognostic (8.62e-2)" "unprognostic (2.51e-2)" "unprognostic (5.40e-2)" "unprognostic (4.09e-2)" "unprognostic (1.06e-1)" "unprognostic (3.14e-2)" "unprognostic (2.92e-2)" "unprognostic (2.63e-1)" "unprognostic (3.78e-2)" "unprognostic (2.78e-2)" 32.2 38.3 58.9 23.5 62.8 28.2 33.9 57.0 74.7 36.7 51.4 31.1 24.6 40.8 43.5 23.9 34.2 29.6 47.8 62.0 70.1 32.2 58.1 28.1 30.5 54.9 58.7 55.7 30.3 40.6 35.7 31.7 58.5 32.7 24.2 32.3 34.4 35.3 44.5 27.0 26.2 32.1 55.9 29.2 29.1 28.0 61.1 29.5 45.2 55.7 31.7 32.8 28.5 58.0 20.1 48.9 25.6 46.6 71.9 53.1 31.3 25.9 42.6 30.0 33.4 26.4 55.5 32.5 34.9 35.5 50.7 45.9 40.3 33.3 23.7 31.2 88.4 48.7 39.9 45.4 47.2 38.4 55.8 44.2 66.3 18.1 37.4 42.1 42.1 41.5 40.6 47.8 47.9 40.8 28.3 40.2 39.5 90.4 16.2 33.9 32.3 51.0 61.5 52.0 34.3 31.3 35.8 37.4 54.3 43.7 35.5 49.8 33.7 31.6 32.5 21.2 28.9 45.0 71.2 35.3 26.9 47.5 26.7 36.4 40.6 81.9 41.2 41.9 46.4 30.6 33.6 31.6 29.1 44.8 44.1 41.4 69.6 52.4 32.4 24.6 38.4 41.3 58.9 62.8 57.0 74.7 62.0 70.1 54.9 58.7 58.5 55.9 61.1 58.0 52.4 25.6 28.7 22.2 55.8 66.3 58.5 142.3 32.5 47.1 42.6 45.8 35.7 35.8 67.9 42.3 33.3 73.7 51.9 23.0 19.6 61.0 8.0 28.1 38.2 48.8 27.0 30.3 41.5 42.3 64.7 53.7 23.0 44.8 25.3 37.6 60.3 56.6 32.3 69.0 55.3 23.2 91.6 42.1 36.4 10.8 73.7 39.2 26.6 37.5 44.4 60.6 56.7 29.1 45.8 27.8 20.7 62.8 41.3 66.6 32.6 39.5 47.2 46.8 72.3 40.1 67.0 89.3 84.2 25.0 55.4 91.0 55.1 21.5 27.8 40.0 TMA7 "CCDC72, HSPC016" ENSG00000232112 "Translation machinery associated 7 homolog" Q9Y2S6 3 48440257-48444208 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047397 Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies" Yes No "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim" "Nucleoplasm, Nuclear bodies" "HPA047397: AB_2680029" "unprognostic (1.26e-3)" "unprognostic (1.21e-1)" "unprognostic (9.10e-2)" "unprognostic (1.18e-2)" "unprognostic (2.06e-1)" "unprognostic (5.02e-2)" "unprognostic (3.55e-2)" "prognostic favorable (8.33e-4)" "unprognostic (1.14e-2)" "unprognostic (3.85e-3)" "unprognostic (1.92e-2)" "unprognostic (2.55e-2)" "unprognostic (1.14e-2)" "unprognostic (9.31e-3)" "unprognostic (3.13e-2)" "unprognostic (1.14e-1)" "unprognostic (8.64e-3)" 252.5 276.8 498.7 220.7 507.8 434.6 241.9 504.6 588.9 236.5 500.2 253.3 192.8 179.4 344.5 310.5 181.7 117.9 355.4 502.2 514.7 317.6 273.2 208.0 279.3 511.7 510.0 259.6 230.3 309.8 302.0 146.6 505.9 239.6 229.3 295.4 215.9 142.7 511.6 215.1 220.4 132.7 513.0 272.9 235.5 216.0 511.9 388.3 232.4 287.4 297.7 213.3 239.3 514.5 565.0 398.8 634.2 456.6 514.0 497.1 435.6 454.1 355.7 425.1 419.3 326.3 395.9 365.2 315.3 397.8 553.6 215.5 559.8 512.5 471.6 452.6 475.5 689.4 910.3 845.8 399.0 792.2 443.0 459.7 538.2 402.6 388.8 414.2 546.0 641.1 376.6 379.0 615.3 581.2 929.4 1071.2 847.1 607.0 637.3 262.2 397.0 620.4 746.0 748.7 207.8 526.1 511.0 369.3 736.1 583.6 356.7 1156.3 412.1 358.0 650.8 560.5 902.6 626.1 1001.6 902.8 459.1 754.2 379.9 1923.2 1058.7 2195.0 1127.1 1022.5 1237.6 1412.6 1486.0 1377.1 1150.8 1172.2 1464.7 1408.1 2036.5 943.8 1028.9 1521.6 1652.1 2663.7 498.7 507.8 504.6 588.9 502.2 514.7 511.7 510.0 505.9 513.0 511.9 514.5 518.8 240.4 370.4 20.9 615.0 716.3 534.0 1308.9 618.6 219.6 866.8 1111.2 633.4 513.3 616.2 901.2 106.3 785.4 797.4 948.2 1717.8 566.9 653.6 524.8 511.4 474.5 635.3 609.1 25.8 1032.9 830.9 443.7 356.3 646.1 454.4 376.5 574.7 1098.6 854.5 119.5 25.4 985.5 695.8 652.4 790.5 1123.9 646.8 544.3 777.3 18.7 850.3 522.8 1080.3 10.1 28.3 872.9 980.3 464.6 593.9 584.6 1211.0 1438.8 466.4 321.9 355.0 393.6 448.4 547.4 689.4 805.5 898.4 440.1 757.1 351.9 937.2 572.2 TMEM107 "JBTS29, MGC10744, MKS13" ENSG00000179029 "Transmembrane protein 107" Q6UX40 17 8172457-8176399 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Developmental protein" "Ciliopathy, Disease variant, Meckel syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 110.8;Respiratory ciliated cells: 164.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052555, HPA059653" Approved Approved "Nucleoplasm,Plasma membrane,Midbody ring" Yes No "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Plasma membrane" "Midbody ring" "HPA052555: AB_2681870, HPA059653: AB_2684096" "unprognostic (2.87e-2)" "unprognostic (2.67e-1)" "unprognostic (2.85e-2)" "prognostic favorable (9.39e-5)" "unprognostic (1.94e-2)" "unprognostic (8.83e-2)" "unprognostic (5.70e-3)" "unprognostic (1.24e-1)" "unprognostic (2.15e-1)" "unprognostic (6.02e-3)" "unprognostic (1.83e-2)" "unprognostic (1.87e-1)" "unprognostic (2.66e-3)" "unprognostic (1.26e-1)" "unprognostic (4.99e-1)" "unprognostic (2.66e-1)" "unprognostic (1.49e-1)" 9.6 13.4 11.1 6.6 12.0 15.0 9.8 12.2 13.3 10.6 19.3 9.0 3.5 11.3 20.7 10.5 27.0 7.2 9.2 11.9 12.8 14.7 4.4 11.3 7.4 13.0 12.6 7.8 11.2 16.9 23.5 6.8 12.2 7.3 5.0 29.6 10.7 6.5 1.6 12.0 7.6 6.6 12.1 13.7 8.0 17.1 12.3 8.9 16.1 1.8 7.6 8.4 9.6 12.5 45.0 16.9 21.8 11.3 12.2 17.8 4.8 11.1 8.2 8.2 10.9 2.0 26.6 10.5 14.6 9.7 7.4 30.5 8.3 16.9 13.6 18.1 11.5 7.6 29.0 4.7 4.9 2.6 8.3 7.9 11.2 20.7 9.4 18.4 13.1 17.7 5.9 23.5 18.0 12.2 6.8 7.7 2.2 6.3 7.2 13.1 6.5 19.1 15.8 3.5 7.3 10.7 13.5 2.4 9.1 5.1 8.1 8.8 10.6 4.8 9.6 7.6 6.1 9.5 5.5 4.9 27.3 10.0 8.7 21.0 22.1 51.6 28.2 27.9 24.3 45.4 27.6 30.3 19.7 59.2 30.9 32.2 20.0 26.4 56.8 31.6 24.8 21.0 11.1 12.0 12.2 13.3 11.9 12.8 13.0 12.6 12.2 12.1 12.3 12.5 30.8 9.6 9.8 2.9 38.1 19.2 19.5 35.2 11.4 17.3 31.1 43.3 7.9 35.8 25.1 33.1 45.9 17.3 30.0 12.9 13.7 21.7 12.2 99.9 22.9 25.1 9.1 15.4 5.1 11.1 21.3 18.2 48.9 26.9 36.7 12.7 27.1 24.0 45.5 11.8 3.6 14.1 16.2 45.6 31.6 10.1 12.8 55.9 33.8 3.7 22.0 37.7 28.8 1.5 1.7 11.0 12.7 15.1 110.8 16.3 26.0 21.7 164.3 63.2 0.0 15.3 16.8 69.4 50.3 13.0 28.6 13.3 34.8 13.2 17.6 11.1 TMEM125 MGC17299 ENSG00000179178 "Transmembrane protein 125" Q96AQ2 1 43269983-43274002 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 75.7;pancreas: 89.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 121.8;Alveolar cells type 2: 136.9;Distal enterocytes: 72.7;Proximal enterocytes: 164.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 26.8;BEWO: 21.8;CACO-2: 20.6;CAPAN-2: 48.3;OE19: 31.3;SK-BR-3: 41.2;T-47d: 33.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015796 Approved Midbody,Cytosol Yes NA "Cluster 40: NK-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" "Midbody, Cytosol" "HPA015796: AB_1858081" "unprognostic (2.53e-3)" "unprognostic (8.70e-2)" "unprognostic (1.27e-1)" "unprognostic (1.52e-1)" "unprognostic (3.14e-2)" "unprognostic (8.50e-2)" "unprognostic (8.37e-3)" "prognostic favorable (5.11e-5)" "unprognostic (3.39e-1)" "unprognostic (1.11e-1)" "unprognostic (7.76e-2)" "unprognostic (1.26e-1)" "prognostic favorable (2.91e-9)" "unprognostic (1.86e-2)" "unprognostic (2.19e-1)" "unprognostic (4.04e-1)" "unprognostic (5.16e-2)" 0.3 0.7 17.4 3.2 32.2 0.2 11.5 27.6 29.9 16.4 12.8 21.2 35.4 1.6 18.3 10.9 15.5 11.3 0.9 17.0 20.7 16.4 1.1 75.7 0.3 31.5 28.5 1.4 89.6 22.2 31.0 4.4 29.0 22.0 21.0 0.1 31.8 7.1 0.0 12.9 27.5 0.8 22.6 0.3 27.4 1.5 26.8 0.4 44.9 0.0 2.5 2.9 3.4 42.8 26.8 0.0 0.0 0.0 0.0 0.0 21.8 0.0 0.0 0.0 0.0 20.6 48.3 0.1 1.2 0.0 0.0 11.7 0.0 7.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 12.1 0.1 0.1 1.1 31.3 0.0 0.0 0.0 0.7 0.4 8.5 12.4 0.1 0.0 41.2 0.0 3.6 33.1 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 17.4 32.2 27.6 29.9 17.0 20.7 31.5 28.5 29.0 22.6 26.8 42.8 0.2 121.8 136.9 0.0 0.9 0.0 2.3 18.0 0.6 0.0 30.4 15.2 0.5 42.9 56.0 16.5 0.0 33.5 0.1 72.7 17.6 39.1 3.7 20.1 1.4 0.6 21.7 0.0 0.2 38.5 2.2 0.6 45.3 13.1 1.3 4.9 0.0 0.0 2.4 0.0 0.2 63.0 34.6 0.0 0.2 7.9 0.3 0.6 0.0 0.0 0.6 1.7 1.0 0.0 55.3 22.7 40.1 1.2 0.6 12.2 164.2 33.9 43.8 0.0 0.0 0.0 2.3 1.4 0.3 2.1 0.4 7.3 1.0 0.1 38.6 9.1 TMEM86B MGC30208 ENSG00000180089 "Transmembrane protein 86B" Q8N661 19 55226638-55228784 "Enzymes, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 11.0;liver: 16.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 37.1;Erythroid cells: 66.5;Hepatocytes: 33.3" "Cancer enriched" "Detected in all" 5 "liver cancer: 10.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 7.6;RPMI-8226: 8.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA057689 Uncertain Uncertain Midbody,Centrosome Yes No "Cluster 32: T-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 39: CACO-2 - Unknown function" "Cluster 6: Erythroid cells - Oxygen transport" Centrosome Midbody "HPA057689: AB_2683504" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (2.76e-5)" "unprognostic (1.87e-1)" "unprognostic (1.29e-1)" "unprognostic (6.55e-2)" "prognostic favorable (3.13e-4)" "unprognostic (1.10e-2)" "unprognostic (2.00e-1)" "unprognostic (2.10e-1)" "prognostic favorable (9.97e-6)" "unprognostic (1.96e-2)" "unprognostic (6.63e-8)" "unprognostic (2.28e-1)" "unprognostic (1.07e-1)" "unprognostic (3.70e-1)" "unprognostic (3.19e-3)" 0.9 2.1 4.6 2.4 5.1 6.9 0.9 4.7 6.8 1.4 3.8 1.8 9.7 1.5 0.1 1.0 1.8 11.0 0.8 4.6 3.9 1.3 16.9 1.2 1.7 4.4 3.7 1.2 0.6 0.5 2.9 0.6 4.3 1.8 0.3 0.7 0.9 0.6 1.5 1.6 10.2 0.3 3.4 3.6 4.1 3.0 4.2 1.6 2.3 0.4 1.2 1.2 1.0 4.2 1.7 0.0 0.9 1.1 0.1 0.0 3.0 1.2 0.3 0.9 0.9 5.4 1.4 2.4 0.4 0.4 0.3 0.7 0.1 0.2 0.0 0.3 4.0 1.9 0.4 7.6 0.9 1.6 0.9 0.7 1.5 0.5 0.0 0.4 0.0 3.8 3.8 1.4 0.4 1.0 3.8 5.3 0.2 0.6 1.7 3.8 0.5 8.1 0.8 1.6 0.7 1.7 0.0 0.9 4.4 0.7 1.0 1.9 1.2 1.9 1.1 1.1 0.9 1.4 1.5 4.1 1.0 5.2 0.4 0.0 0.3 0.2 0.4 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.2 0.5 0.3 0.2 0.0 0.6 0.0 0.2 4.6 5.1 4.7 6.8 4.6 3.9 4.4 3.7 4.3 3.4 4.2 4.2 1.5 6.4 2.7 4.9 1.3 3.3 0.4 1.0 1.8 6.0 1.9 1.1 0.6 37.1 1.5 0.0 2.1 0.4 1.9 2.0 0.0 1.1 3.0 2.5 1.0 1.9 10.7 66.5 5.2 0.2 0.3 0.9 12.8 1.8 0.0 2.5 1.4 33.3 1.0 10.1 4.5 2.8 4.1 5.9 2.8 4.5 0.9 2.5 3.6 0.0 3.1 1.2 2.1 2.5 3.3 1.1 0.3 0.4 2.9 1.2 14.5 1.0 3.8 3.9 0.0 0.8 1.3 1.8 1.2 0.8 2.3 0.3 3.3 1.9 2.7 2.4 TMEM9 TMEM9A ENSG00000116857 "Transmembrane protein 9" Q9P0T7 1 201134772-201171574 "Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008483 Approved "Vesicles,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA008483: " "unprognostic (1.88e-1)" "prognostic unfavorable (6.57e-4)" "unprognostic (2.95e-1)" "unprognostic (3.67e-2)" "unprognostic (3.96e-1)" "prognostic unfavorable (3.93e-4)" "unprognostic (1.05e-2)" "unprognostic (1.47e-1)" "unprognostic (1.53e-2)" "unprognostic (1.69e-2)" "unprognostic (2.46e-2)" "unprognostic (2.99e-1)" "unprognostic (1.88e-2)" "unprognostic (2.38e-1)" "unprognostic (9.17e-2)" "unprognostic (3.32e-1)" "unprognostic (9.90e-2)" 34.1 102.3 103.1 20.8 104.4 27.8 45.0 93.5 126.6 76.8 122.7 45.0 25.4 70.9 65.4 31.1 75.4 39.5 51.3 107.8 113.2 73.8 73.8 44.5 23.5 99.4 111.5 81.4 73.9 92.2 63.4 28.5 102.8 60.3 25.4 43.9 60.7 45.9 44.9 35.5 30.4 37.5 100.2 31.2 49.8 67.0 112.5 26.3 68.5 24.9 17.7 45.7 51.8 100.2 63.1 117.0 72.6 168.9 38.5 54.5 128.5 48.6 51.5 76.0 68.2 115.7 99.8 33.2 69.2 73.4 70.1 123.3 76.5 80.1 37.3 21.3 131.9 58.1 182.4 76.6 73.8 28.2 51.9 65.0 87.0 71.2 43.0 91.3 47.7 46.2 105.6 35.5 66.2 81.0 34.1 46.1 111.0 57.3 285.3 60.7 108.4 44.0 87.9 48.0 67.6 137.7 86.7 146.9 91.8 107.4 180.3 48.5 35.7 84.8 70.0 68.5 59.8 143.9 135.2 26.1 64.4 30.1 42.0 49.8 59.8 33.7 45.7 41.8 52.2 54.5 44.0 37.8 51.5 49.2 64.6 42.7 41.0 32.9 38.5 56.1 43.0 75.5 103.1 104.4 93.5 126.6 107.8 113.2 99.4 111.5 102.8 100.2 112.5 100.2 20.9 51.3 49.5 17.0 13.4 12.9 31.4 65.6 27.3 61.0 56.2 65.7 39.3 40.0 48.0 36.8 31.3 44.4 9.3 7.9 17.6 88.8 58.0 37.3 58.6 26.3 31.8 43.6 15.7 74.7 52.1 59.9 20.9 46.4 13.3 46.3 30.0 40.4 28.1 8.4 22.1 26.9 36.7 13.4 11.9 60.9 70.8 15.6 23.2 8.4 11.8 102.3 25.7 15.6 10.1 40.3 18.8 53.0 18.8 28.5 8.3 56.9 54.5 32.8 13.1 33.3 42.1 54.8 76.7 14.5 13.9 13.0 13.0 130.7 28.4 27.8 TMPPE FLJ45032 ENSG00000188167 "Transmembrane protein with metallophosphoesterase domain" Q6ZT21 3 33090421-33097146 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 5.5" "Cell type enhanced" "Detected in some" "Rod photoreceptor cells: 2.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.4" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 6 "BEWO: 27.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027019 Approved Approved Nucleoplasm,Mitochondria Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Mitochondria" "HPA027019: AB_1848942" "unprognostic (1.14e-2)" "unprognostic (1.48e-1)" "unprognostic (1.00e-1)" "unprognostic (1.37e-1)" "unprognostic (5.03e-2)" "unprognostic (2.96e-2)" "unprognostic (6.34e-3)" "unprognostic (8.14e-2)" "unprognostic (1.96e-1)" "unprognostic (1.71e-1)" "unprognostic (1.25e-3)" "unprognostic (9.58e-2)" "unprognostic (1.60e-7)" "unprognostic (1.61e-1)" "unprognostic (5.40e-2)" "unprognostic (2.13e-1)" "unprognostic (4.33e-2)" 0.6 0.5 0.8 1.4 0.7 5.5 0.6 0.7 1.2 0.6 4.3 1.0 1.2 0.5 0.6 0.6 0.9 0.6 0.4 1.5 0.5 1.0 0.6 1.1 1.1 1.4 1.4 0.6 0.7 1.9 0.3 1.2 1.6 0.5 1.2 2.8 0.7 0.6 0.2 1.1 1.1 0.8 0.2 1.5 1.3 0.3 1.7 0.5 1.0 0.3 1.3 0.8 0.4 0.2 1.4 1.9 1.0 1.7 1.2 1.0 27.2 0.6 1.0 1.6 0.9 2.7 3.8 0.8 1.2 1.7 0.9 1.4 1.7 1.5 2.6 4.2 0.6 3.4 1.9 2.1 0.9 3.0 4.7 1.1 1.2 2.0 1.4 0.8 1.9 1.7 2.6 2.9 1.2 1.3 1.2 1.3 1.0 0.4 1.1 1.5 0.6 1.9 1.5 1.9 0.2 0.6 0.9 2.6 0.6 1.3 1.4 4.2 2.7 2.4 3.0 1.3 2.6 2.3 1.6 0.4 3.0 2.2 1.7 0.0 1.1 0.3 0.1 2.4 0.6 0.3 0.2 0.0 1.0 0.1 0.0 0.0 1.9 0.0 1.1 0.2 0.2 0.4 0.8 0.7 0.7 1.2 1.5 0.5 1.4 1.4 1.6 0.2 1.7 0.2 0.3 0.0 1.3 0.0 0.8 0.8 0.1 0.0 0.0 1.2 0.4 0.4 0.4 0.0 0.2 0.0 0.0 1.1 1.9 1.4 0.0 0.4 0.0 0.8 0.6 0.4 0.0 0.4 0.0 0.8 1.7 0.3 0.0 1.1 0.0 0.4 0.4 0.6 0.9 1.7 0.0 0.2 2.0 1.3 1.2 0.0 0.0 1.1 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.5 1.4 0.4 1.0 0.2 1.4 0.3 0.4 2.2 0.0 0.2 0.7 0.0 0.0 1.5 0.9 0.4 0.6 0.5 0.6 0.2 TNPO2 "FLJ12155, IPO3, KPNB2B, TRN2" ENSG00000105576 "Transportin 2" O14787 19 12699194-12724011 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 100.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046446, HPA071498" Approved Approved Nucleoplasm,Nucleoli Yes No "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nucleoli" "CAB046446: AB_10603392, HPA071498: AB_2686405" "unprognostic (1.88e-1)" "unprognostic (1.07e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (7.16e-5)" "unprognostic (2.25e-1)" "unprognostic (3.64e-2)" "unprognostic (2.72e-2)" "unprognostic (6.75e-2)" "unprognostic (3.44e-1)" "unprognostic (1.79e-1)" "unprognostic (1.79e-2)" "unprognostic (4.63e-2)" "prognostic favorable (8.18e-4)" "unprognostic (2.76e-3)" "unprognostic (6.00e-2)" "unprognostic (3.50e-3)" "unprognostic (7.63e-2)" 28.3 33.0 50.3 21.7 54.4 26.8 24.8 36.7 57.3 30.9 28.2 28.4 17.3 33.3 25.5 31.3 30.3 20.5 26.6 54.6 44.1 22.5 18.4 23.0 23.4 51.3 45.4 40.3 20.6 32.3 33.6 20.9 50.9 26.6 19.8 33.0 22.2 23.9 25.7 48.1 23.4 28.1 39.5 26.3 23.5 32.7 51.5 27.8 26.8 20.1 23.9 28.6 27.6 51.2 54.4 40.5 61.0 78.3 36.3 47.6 39.5 61.0 40.1 86.5 60.6 55.9 28.5 36.6 46.5 51.7 24.1 70.5 109.2 60.3 47.9 45.6 87.6 56.5 72.1 68.4 40.9 100.6 52.0 42.9 46.8 57.5 60.4 55.8 41.0 72.7 89.4 33.9 48.5 93.4 84.8 68.8 71.0 39.8 120.8 80.7 47.6 67.0 51.2 38.9 148.6 73.8 49.6 62.2 30.7 41.2 43.5 35.2 41.5 131.5 34.9 71.3 91.2 66.8 70.4 62.3 39.2 89.9 47.9 0.2 0.2 0.1 0.6 0.3 0.9 0.4 0.4 0.5 0.4 0.4 0.8 1.0 0.8 0.1 0.4 1.5 0.2 0.2 50.3 54.4 36.7 57.3 54.6 44.1 51.3 45.4 50.9 39.5 51.5 51.2 13.2 6.4 17.9 24.2 10.7 31.0 8.9 10.6 14.8 42.4 22.8 17.1 17.6 11.5 10.0 22.0 100.1 10.9 11.0 14.1 5.9 9.7 12.2 16.2 20.6 17.0 22.9 14.9 22.3 8.5 6.6 18.0 10.2 12.9 3.8 20.7 19.2 17.8 10.5 57.2 26.6 17.7 8.2 13.0 14.9 19.5 31.1 8.7 8.8 22.5 11.1 24.6 6.2 19.6 24.7 15.2 9.1 32.4 8.7 19.3 11.9 16.7 11.3 33.6 6.6 23.8 15.3 23.8 11.3 21.9 41.5 14.5 9.5 16.5 16.6 9.3 TOP2A TOP2 ENSG00000131747 "DNA topoisomerase II alpha" P11388 17 40388525-40417896 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 127.8;testis: 65.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 216.8;Granulosa cells: 117.5;Spermatocytes: 621.2;Spermatogonia: 269.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 2.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 4.2;white matter: 8.0" "Low region specificity" "Detected in some" "CAB002448, HPA006458, HPA026773" Enhanced Approved Supported Nucleoplasm,Nucleoli Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "CAB002448: AB_564035, HPA006458: AB_1858189, HPA026773: AB_1858190" "unprognostic (2.09e-1)" "unprognostic (1.24e-1)" "unprognostic (2.28e-3)" "unprognostic (9.42e-3)" "unprognostic (1.80e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.92e-6)" "prognostic unfavorable (4.99e-4)" "unprognostic (6.21e-3)" "unprognostic (2.09e-1)" "prognostic unfavorable (3.83e-5)" "unprognostic (5.03e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.46e-2)" "unprognostic (1.07e-1)" "unprognostic (2.18e-1)" "unprognostic (2.29e-1)" 2.2 2.5 0.2 20.0 0.2 42.0 5.4 0.1 0.7 5.0 1.1 17.8 18.1 3.9 0.3 29.0 1.5 2.6 1.2 0.2 0.2 1.2 2.8 4.1 40.3 0.2 0.8 1.0 0.9 0.3 0.3 15.9 0.5 1.4 19.8 0.1 4.3 0.5 0.3 15.3 17.0 7.6 0.2 9.9 8.9 65.7 1.1 127.8 1.9 0.2 42.5 6.0 9.6 0.4 212.6 275.6 343.1 158.0 16.8 33.9 76.3 283.3 151.5 255.0 224.2 130.5 157.6 339.4 140.1 96.7 152.7 326.5 266.8 113.5 339.5 182.7 177.8 224.8 167.9 216.7 1.6 318.4 228.6 7.4 9.2 179.8 181.4 55.1 136.3 216.5 247.5 225.8 279.2 72.6 372.3 209.6 143.0 152.4 108.3 310.7 531.9 141.3 61.6 133.3 201.6 144.6 229.3 281.4 89.4 198.2 236.9 143.2 90.3 167.0 233.2 195.5 276.7 128.4 154.9 290.7 94.3 214.9 285.0 0.2 0.0 0.0 0.2 0.0 0.0 0.6 0.3 0.3 0.1 0.1 0.0 0.0 0.1 1.4 0.1 0.0 2.4 0.4 0.2 0.2 0.1 0.7 0.2 0.2 0.2 0.8 0.5 0.2 1.1 0.4 1.0 0.0 2.0 0.3 17.4 11.7 3.7 15.0 2.2 0.0 18.7 17.1 1.3 2.8 5.8 0.0 0.0 72.9 6.1 19.8 0.0 0.8 20.3 12.7 15.8 9.3 0.0 216.8 0.2 0.0 92.4 23.3 23.0 10.0 0.0 117.5 20.7 5.4 83.5 0.0 0.1 34.2 18.3 33.9 13.2 19.1 4.7 14.1 1.8 0.0 2.6 0.0 3.1 0.0 0.1 0.3 3.5 1.9 31.3 3.1 3.4 0.1 1.8 0.0 72.3 0.5 19.5 621.2 269.6 45.1 6.1 8.9 14.8 4.3 61.0 6.9 TP53 "LFS1, p53" ENSG00000141510 "Tumor protein p53" P04637 17 7661779-7687538 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters" "Apoptosis, Biological rhythms, Cell cycle, Host-virus interaction, Necrosis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002973, CAB039238, CAB039239, HPA051244, HPA063532, CAB072876, CAB079965" Enhanced Supported Nucleoplasm,Mitochondria,Cytosol Yes No "Cluster 39: Non-specific - mRNA processing" "Cluster 3: T-cells - Adaptive immune response" "Cluster 14: REH - Unknown function" "Cluster 32: Non-specific - Translation" Nucleoplasm "Mitochondria, Cytosol" "CAB002973: AB_2206626, CAB039238: , CAB039239: , CAB072876: AB_2665731, CAB079965: , HPA051244: AB_2681403, HPA063532: " "unprognostic (2.29e-2)" "unprognostic (8.83e-3)" "unprognostic (1.26e-2)" "prognostic favorable (1.35e-4)" "unprognostic (9.95e-2)" "unprognostic (4.00e-2)" "unprognostic (2.79e-3)" "unprognostic (4.99e-2)" "unprognostic (2.75e-2)" "unprognostic (2.55e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (5.01e-4)" "unprognostic (1.86e-3)" "unprognostic (7.89e-3)" "unprognostic (8.05e-2)" "unprognostic (2.74e-1)" "unprognostic (1.08e-1)" 19.3 13.8 10.4 27.1 12.6 19.6 22.5 10.4 16.5 19.9 10.3 29.0 18.9 24.5 12.8 28.8 31.3 13.2 11.1 10.1 11.4 14.9 16.5 15.1 34.6 18.7 13.6 27.3 18.3 9.4 7.3 23.5 12.5 17.7 27.5 4.1 18.9 15.3 12.3 37.4 20.4 24.6 12.6 31.1 22.6 10.4 12.3 47.2 17.4 6.1 45.4 20.8 19.9 13.3 81.5 145.3 81.1 57.3 37.3 43.9 82.8 28.4 66.1 78.5 100.2 4.2 40.6 190.5 126.9 58.7 77.6 174.9 119.7 80.4 72.8 42.7 76.5 77.6 76.8 70.9 111.5 1.6 37.0 55.7 93.0 38.9 106.5 45.6 79.4 24.7 3.8 6.9 41.5 145.1 130.0 96.3 80.2 10.4 2.4 252.2 56.1 66.2 59.4 87.3 46.0 80.5 94.1 62.6 24.3 39.4 109.2 7.4 100.7 91.6 30.2 1.0 48.3 47.6 37.9 82.5 23.6 9.7 80.1 1.2 21.2 3.4 13.0 21.7 15.9 21.5 13.3 14.6 30.3 19.1 13.7 15.4 2.4 17.5 19.3 27.3 17.3 14.7 10.4 12.6 10.4 16.5 10.1 11.4 18.7 13.6 12.5 12.6 12.3 13.3 21.1 9.6 12.8 16.3 26.0 28.7 14.5 24.6 24.5 2.6 36.1 30.4 2.5 18.6 15.4 20.2 0.0 36.9 24.7 16.9 9.8 24.8 12.8 11.5 29.0 24.5 30.7 21.7 2.1 18.1 39.6 17.0 11.2 19.5 1.3 31.7 22.1 18.0 24.2 0.0 3.2 43.0 18.3 27.8 20.1 3.8 23.0 19.3 12.4 7.5 31.9 4.9 25.7 9.0 8.0 15.8 16.4 17.0 7.8 15.7 10.3 10.1 8.8 2.6 13.1 25.9 20.6 0.5 4.9 28.7 32.8 22.4 16.5 27.4 54.1 11.5 TP53BP1 "53BP1, p202, TDRD30" ENSG00000067369 "Tumor protein p53 binding protein 1" Q12888 15 43403061-43510728 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004083, HPA008788, HPA022133, CAB079980" Supported Supported "Nucleoplasm,Nuclear bodies,Mitotic chromosome,Vesicles" Yes No "Cluster 46: Basophils - DNA binding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "Nuclear bodies" "Nucleoplasm, Mitotic chromosome, Vesicles" "CAB004083: AB_10694558, CAB079980: , HPA008788: AB_1078070, HPA022133: AB_1844382" "unprognostic (2.12e-1)" "unprognostic (7.96e-2)" "unprognostic (1.11e-1)" "unprognostic (1.85e-2)" "unprognostic (4.42e-3)" "unprognostic (2.32e-1)" "unprognostic (2.03e-2)" "unprognostic (3.96e-1)" "unprognostic (2.17e-1)" "unprognostic (2.81e-2)" "unprognostic (3.34e-2)" "unprognostic (4.07e-1)" "unprognostic (8.06e-2)" "unprognostic (9.11e-2)" "unprognostic (1.52e-1)" "unprognostic (6.99e-2)" "unprognostic (3.38e-2)" 6.9 11.5 17.4 10.1 16.6 11.5 10.7 19.9 14.5 17.7 21.5 9.7 6.4 16.0 15.9 6.1 14.7 10.7 8.8 15.4 26.3 9.1 4.1 8.3 8.6 13.5 16.7 16.8 7.4 22.3 24.1 12.2 15.7 12.1 10.2 22.0 10.1 12.8 7.2 9.2 6.4 16.3 9.6 8.7 7.6 21.6 23.0 15.3 17.9 11.0 12.6 11.2 8.7 12.1 13.5 22.3 63.8 40.1 25.8 31.9 15.8 22.8 33.8 31.0 39.1 19.4 15.8 14.5 19.2 39.0 66.9 32.4 46.3 27.5 36.8 38.9 15.8 27.1 40.1 11.7 16.8 30.2 37.4 24.9 19.0 41.8 31.2 51.7 37.4 24.2 26.9 12.3 36.5 9.6 23.7 14.1 41.1 24.2 13.9 25.1 23.9 9.3 22.9 31.8 57.3 26.8 33.8 14.3 8.5 48.6 29.9 16.9 27.5 33.7 22.3 27.0 20.5 9.8 22.4 33.0 27.6 14.6 17.5 1.4 0.5 1.0 1.6 0.7 1.3 1.9 1.6 1.6 1.2 1.8 1.8 1.6 0.6 0.9 0.5 1.3 1.4 0.7 17.4 16.6 19.9 14.5 15.4 26.3 13.5 16.7 15.7 9.6 23.0 12.1 11.5 22.4 22.3 53.2 17.8 6.4 10.2 10.0 13.6 32.4 17.4 13.2 14.9 5.7 20.8 29.5 47.9 13.4 11.1 7.4 9.8 14.5 38.8 47.0 44.8 16.8 41.9 8.4 66.2 7.1 11.2 23.9 14.8 26.8 26.6 47.0 15.0 3.3 10.8 47.1 81.9 15.7 12.2 3.8 6.9 17.8 23.6 9.3 1.8 17.8 4.0 11.9 7.2 62.8 50.4 7.5 5.8 17.7 17.1 11.0 2.6 8.8 60.7 51.7 13.1 35.2 20.5 33.1 36.2 14.7 5.3 18.5 17.0 29.9 13.4 8.9 TP53TG5 "C20orf10, CLG01, dJ453C12.5" ENSG00000124251 "TP53 target 5" Q9Y2B4 20 45372557-45407889 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 17.8" "Cell type enhanced" "Detected in some" "Early spermatids: 671.5;Late spermatids: 254.4;Oligodendrocytes: 157.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041979, HPA058510, HPA077455" Enhanced Supported "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes NA "Cluster 78: Testis - Spermatogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA041979: AB_2677778, HPA058510: , HPA077455: " "unprognostic (2.86e-1)" "unprognostic (1.28e-1)" "unprognostic (2.18e-1)" "unprognostic (3.40e-3)" "unprognostic (1.70e-1)" "unprognostic (1.63e-3)" "unprognostic (2.29e-3)" "unprognostic (3.10e-3)" "unprognostic (9.26e-2)" "unprognostic (3.56e-2)" "unprognostic (1.72e-5)" "unprognostic (2.09e-2)" "unprognostic (7.46e-2)" "unprognostic (1.48e-1)" "unprognostic (1.46e-1)" "unprognostic (4.72e-4)" "unprognostic (1.41e-1)" 0.1 0.1 1.1 0.2 1.8 0.7 0.1 0.9 2.6 0.1 1.4 0.3 0.1 0.2 0.4 0.1 0.2 0.2 0.2 1.1 1.5 0.1 0.1 0.2 0.4 1.8 1.5 0.1 0.1 0.0 0.2 0.1 2.0 0.1 0.0 0.8 0.2 0.0 0.2 0.2 0.2 0.0 0.7 0.2 0.2 17.8 1.7 0.0 0.2 0.0 0.0 0.2 0.1 3.5 0.3 0.7 0.4 1.1 0.0 0.0 0.3 0.2 0.0 0.0 0.0 2.1 0.3 0.3 0.2 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.3 0.4 1.0 0.6 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.4 0.1 0.0 0.5 0.4 0.3 0.1 0.3 0.3 0.0 0.2 0.2 0.0 0.4 0.4 0.3 1.0 0.4 0.2 0.1 1.1 0.1 0.6 1.4 0.4 0.9 0.2 0.3 0.4 0.0 0.7 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.8 0.9 2.6 1.1 1.5 1.8 1.5 2.0 0.7 1.7 3.5 0.1 0.0 0.0 2.9 0.0 0.1 0.4 0.0 0.0 0.8 0.5 0.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 671.5 0.5 0.2 0.3 0.0 0.0 7.6 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 7.8 0.5 0.0 0.0 1.1 254.4 4.7 0.1 0.0 1.9 0.0 0.1 0.0 2.5 157.5 0.0 1.2 4.5 0.0 0.2 0.2 0.1 0.3 1.0 0.0 0.4 1.2 2.1 1.8 0.0 1.1 0.0 0.1 0.0 0.3 0.9 TPX2 "C20orf1, C20orf2, DIL-2, p100" ENSG00000088325 "TPX2 microtubule nucleation factor" Q9ULW0 20 31739271-31801805 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 48.0;lymphoid tissue: 70.3;testis: 30.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 90.7;Extravillous trophoblasts: 68.5;Granulosa cells: 46.6;Spermatocytes: 114.5;Spermatogonia: 63.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 8.1" "Group enriched" "Detected in many" 5 "granulocytes: 5.1;NK-cells: 3.6;T-cells: 8.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005487 Enhanced Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cytokinetic bridge, Mitotic spindle" "HPA005487: AB_1858223" "unprognostic (2.18e-2)" "unprognostic (1.77e-1)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.43e-6)" "unprognostic (2.99e-1)" "unprognostic (7.56e-2)" "prognostic unfavorable (8.07e-7)" "prognostic unfavorable (6.46e-4)" "unprognostic (3.70e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.68e-5)" "unprognostic (5.99e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.56e-2)" "unprognostic (2.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.39e-1)" 1.9 1.4 0.9 13.0 0.9 48.0 2.7 0.8 1.0 2.3 0.5 11.6 9.4 2.4 0.2 13.2 0.9 1.8 0.8 1.1 0.6 0.7 4.2 1.9 26.6 0.6 1.0 0.5 0.4 0.4 0.2 8.3 0.7 0.7 14.2 0.5 2.0 0.5 1.4 9.8 9.4 6.8 0.6 5.2 6.2 30.7 1.3 70.3 1.0 0.8 32.3 3.4 4.1 0.9 455.1 149.1 176.4 139.1 13.8 25.2 169.8 186.1 104.5 264.0 197.7 319.1 190.4 212.4 106.7 104.5 196.8 232.7 203.7 169.0 298.8 92.3 78.8 416.3 139.7 219.6 4.2 161.9 102.8 8.7 9.1 166.0 120.0 37.9 144.6 157.1 313.8 187.8 209.7 186.2 272.2 125.3 197.1 174.0 159.3 152.5 475.5 128.2 71.2 72.8 127.5 85.7 284.6 106.3 82.0 120.9 185.1 97.3 98.3 294.1 179.7 136.5 290.0 74.4 138.6 187.3 92.2 565.1 195.8 5.1 0.0 0.4 0.4 0.0 0.2 0.6 1.4 1.7 0.5 0.2 0.3 0.5 0.2 3.6 0.1 1.0 8.1 1.0 0.9 0.9 0.8 1.0 1.1 0.6 0.6 1.0 0.7 0.6 1.3 0.9 1.0 0.0 4.2 0.0 5.9 6.9 1.5 4.3 1.2 0.9 3.0 3.4 0.9 4.3 3.8 0.0 0.0 23.3 3.8 6.4 0.0 1.2 9.3 7.3 6.6 3.9 1.2 90.7 2.9 0.4 68.5 9.2 16.3 8.4 0.0 46.6 8.9 3.0 19.5 1.7 0.9 9.8 10.2 8.0 5.5 13.1 0.9 7.6 0.0 1.0 2.1 0.4 3.1 0.5 0.5 1.8 1.4 0.0 30.8 2.5 0.9 0.0 0.7 0.4 0.0 1.1 15.4 114.5 63.1 31.2 6.1 4.7 8.2 4.2 18.4 2.9 TRAT1 "HSPC062, TCRIM, TRIM" ENSG00000163519 "T cell receptor associated transmembrane adaptor 1" Q6PIZ9 3 108822770-108855005 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "lymphoid tissue: 79.8" "Cell type enriched" "Detected in some" 10 "T-cells: 129.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 395.1" "Group enriched" "Detected in many" 155 "granulocytes: 395.1;T-cells: 313.1" "Group enriched" "Detected in some" 25 "JURKAT: 29.9;MOLT-4: 76.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA002356, CAB026130, HPA072760" Enhanced Enhanced "Plasma membrane,Mitotic spindle,Centriolar satellite" Yes NA "Cluster 32: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Mitotic spindle, Centriolar satellite" "CAB026130: , HPA002356: AB_1080375, HPA072760: " "unprognostic (1.54e-4)" "unprognostic (1.41e-3)" "unprognostic (6.82e-2)" "unprognostic (4.95e-3)" "unprognostic (2.84e-2)" "unprognostic (2.19e-3)" "unprognostic (1.87e-3)" "unprognostic (2.02e-2)" "unprognostic (7.21e-3)" "unprognostic (8.96e-3)" "unprognostic (8.03e-2)" "unprognostic (4.32e-1)" "unprognostic (2.86e-5)" "unprognostic (3.12e-1)" "unprognostic (3.01e-2)" "unprognostic (2.90e-4)" "unprognostic (4.36e-2)" 1.1 0.6 0.0 11.0 0.0 2.7 0.8 0.0 0.0 0.4 0.0 1.3 1.4 0.4 0.4 1.0 0.3 2.5 0.4 0.1 0.0 0.3 1.3 2.1 23.9 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.8 1.5 0.0 0.6 0.1 0.1 0.6 3.0 0.5 0.0 8.5 2.4 0.4 0.0 79.8 0.4 0.4 12.4 2.9 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.9 0.0 2.1 0.0 0.0 76.0 0.0 0.0 0.0 0.0 0.6 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 395.1 0.6 0.2 57.0 0.2 116.4 1.0 229.5 119.6 0.3 0.4 313.1 77.7 3.5 2.2 0.7 0.8 111.1 139.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 3.2 0.0 3.3 8.4 0.1 0.0 0.0 0.0 0.4 0.3 0.3 0.0 0.0 1.8 0.0 0.0 8.9 0.1 0.0 0.0 2.3 0.1 0.1 1.1 0.0 2.7 0.1 0.0 0.0 1.7 7.7 0.1 2.5 0.0 1.8 0.6 0.2 0.0 0.2 0.0 0.0 1.0 12.2 2.2 0.0 1.8 3.6 0.0 3.2 0.0 3.1 0.0 0.2 0.0 0.0 0.0 5.1 0.2 0.0 0.5 0.0 0.0 0.0 0.3 0.8 0.0 0.1 0.0 8.0 0.1 129.3 0.6 0.0 0.2 TRIM45 "FLJ13181, RNF99" ENSG00000134253 "Tripartite motif containing 45" Q9H8W5 1 117111060-117122587 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 29.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Cardiomyocytes: 12.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 31.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030266, HPA054308" Uncertain Supported "Cytokinetic bridge,Cytosol" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "Cytokinetic bridge" "HPA030266: AB_10795476, HPA054308: AB_2682445" "prognostic favorable (1.58e-4)" "unprognostic (2.68e-2)" "unprognostic (1.12e-2)" "unprognostic (3.49e-1)" "unprognostic (5.70e-2)" "unprognostic (9.66e-2)" "unprognostic (2.19e-3)" "unprognostic (1.16e-2)" "unprognostic (1.26e-2)" "unprognostic (1.43e-2)" "unprognostic (3.05e-1)" "unprognostic (5.45e-2)" "unprognostic (7.09e-2)" "unprognostic (3.90e-2)" "unprognostic (4.85e-2)" "prognostic unfavorable (2.92e-4)" "unprognostic (1.27e-2)" 2.9 7.1 3.9 1.2 3.6 2.1 5.4 2.9 3.9 7.3 3.1 6.2 3.7 8.7 6.6 2.2 10.0 2.9 12.6 3.4 3.1 6.7 1.7 2.4 0.9 3.3 3.2 9.1 11.4 5.6 10.5 2.0 3.0 10.7 2.1 3.6 4.7 5.7 29.1 5.8 3.1 4.9 3.2 3.2 5.7 7.6 3.7 0.8 12.0 10.5 0.6 8.1 5.3 3.8 4.3 3.6 16.0 7.5 1.3 3.6 11.9 4.8 2.0 3.3 3.3 1.8 3.9 0.1 3.5 2.2 3.5 3.9 3.7 3.9 4.4 2.5 3.8 2.6 13.9 2.1 2.3 2.4 3.6 4.6 3.8 5.5 3.9 6.2 4.1 4.7 3.2 3.2 3.1 19.3 1.4 2.7 8.7 2.5 3.5 6.1 31.4 0.9 4.5 3.9 11.9 3.1 3.9 3.6 3.1 15.0 6.2 3.1 1.4 4.6 6.6 2.8 4.3 8.7 3.5 0.3 6.0 2.2 12.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.5 0.0 3.9 3.6 2.9 3.9 3.4 3.1 3.3 3.2 3.0 3.2 3.7 3.8 1.1 9.6 2.7 4.9 0.1 1.1 1.8 1.5 1.2 1.4 5.0 3.4 12.2 4.3 2.2 1.8 4.2 2.7 0.1 0.3 1.9 1.9 5.7 2.8 2.6 1.5 1.8 2.5 2.5 3.2 1.2 2.1 3.6 2.8 0.0 4.0 2.2 0.2 0.8 1.7 1.9 1.6 0.0 0.3 0.3 2.7 1.8 0.4 0.0 3.7 0.0 1.4 0.0 3.5 2.3 2.1 0.0 1.9 0.6 0.5 0.4 0.4 1.9 1.4 0.0 3.1 2.1 6.1 5.3 1.3 1.6 1.1 0.4 5.5 1.6 1.3 TRMT11 "C6orf75, dJ187J11.2, MDS024, TRM11, TRMT11-1" ENSG00000066651 "TRNA methyltransferase 11 homolog" Q7Z4G4 6 125986479-126203817 "Metabolic proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030473 Approved "Nuclear bodies" Yes No "Cluster 30: Non-specific - Translation" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" "Nuclear bodies" "HPA030473: AB_2673493" "unprognostic (2.55e-1)" "unprognostic (6.12e-3)" "unprognostic (1.44e-1)" "unprognostic (1.13e-2)" "unprognostic (7.62e-2)" "unprognostic (9.69e-2)" "unprognostic (2.12e-1)" "unprognostic (7.38e-2)" "unprognostic (3.54e-2)" "unprognostic (5.73e-2)" "unprognostic (7.35e-2)" "unprognostic (1.06e-2)" "unprognostic (4.74e-3)" "unprognostic (1.14e-1)" "unprognostic (1.30e-1)" "unprognostic (1.69e-1)" "unprognostic (2.06e-1)" 8.4 10.2 7.3 8.1 7.5 2.9 11.7 12.9 9.9 9.5 6.6 8.8 12.8 13.5 9.9 8.0 9.7 9.0 10.9 7.3 7.8 13.3 19.8 7.9 10.5 6.7 7.4 12.5 6.4 12.6 13.3 9.4 7.2 9.1 9.4 16.9 8.8 8.5 7.6 6.6 10.7 10.7 5.8 6.8 8.8 7.7 7.2 8.7 12.9 8.8 10.4 9.6 8.9 9.0 17.4 11.0 24.2 11.4 12.9 13.7 16.6 13.1 21.7 15.6 24.3 30.8 19.8 26.0 24.2 8.3 29.1 20.7 26.1 14.3 26.4 19.5 37.6 17.8 20.1 46.2 21.9 29.0 5.4 14.3 15.5 15.9 25.6 22.4 7.6 9.1 44.5 5.3 17.7 22.0 15.3 34.6 20.4 15.4 15.1 9.1 16.3 17.6 22.3 9.8 32.4 16.9 13.9 18.0 36.3 18.0 13.1 28.3 5.4 9.7 10.7 27.3 25.8 13.9 1.3 6.6 23.2 24.5 17.7 1.0 1.6 0.0 5.6 1.3 11.0 7.0 7.9 6.5 3.5 6.0 9.5 8.6 0.5 7.7 0.7 4.3 6.0 3.2 7.3 7.5 12.9 9.9 7.3 7.8 6.7 7.4 7.2 5.8 7.2 9.0 11.0 6.4 22.0 24.8 17.4 13.4 27.8 29.4 23.3 59.5 11.2 13.7 12.2 21.5 26.1 7.3 73.0 18.7 14.9 8.5 19.6 19.2 10.1 13.1 25.5 10.4 9.1 8.4 56.1 16.3 13.7 27.3 27.0 12.3 18.4 20.0 6.8 22.5 7.2 20.2 63.8 11.1 18.3 6.0 3.7 4.7 25.7 7.1 3.6 23.4 11.8 21.1 9.2 31.7 48.5 13.2 15.5 24.5 12.3 22.6 22.6 30.2 24.3 74.7 6.6 21.0 17.2 15.6 9.2 14.3 10.1 14.9 14.7 27.2 13.7 17.9 TRNT1 "CCA1, CGI-47, MtCCA" ENSG00000072756 "TRNA nucleotidyl transferase 1" Q96Q11 3 3126933-3150879 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Nucleotidyltransferase, RNA-binding, Transferase" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036938 Uncertain Supported Mitochondria Yes No "Cluster 46: Basophils - DNA binding" "Cluster 7: Kidney - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA036938: AB_10670566" "unprognostic (6.39e-3)" "unprognostic (1.58e-1)" "unprognostic (2.38e-3)" "unprognostic (4.69e-2)" "unprognostic (4.92e-2)" "unprognostic (2.41e-1)" "unprognostic (1.39e-2)" "unprognostic (2.68e-1)" "unprognostic (6.22e-2)" "unprognostic (5.65e-2)" "unprognostic (4.62e-2)" "unprognostic (1.41e-2)" "unprognostic (1.24e-2)" "unprognostic (6.50e-2)" "unprognostic (1.09e-1)" "unprognostic (3.78e-1)" "unprognostic (1.02e-1)" 9.7 10.0 7.2 8.9 7.2 3.5 8.5 7.9 8.0 7.8 7.0 8.1 4.4 8.8 5.5 9.4 7.6 8.3 8.4 7.4 7.2 17.2 10.0 8.4 9.7 7.1 7.3 8.3 8.4 8.3 10.3 10.5 7.1 11.3 7.6 4.0 7.7 6.3 9.3 6.4 7.9 8.3 7.3 10.7 9.1 6.5 7.4 9.8 11.3 7.6 10.9 13.1 7.9 8.0 20.0 29.6 18.2 9.8 24.1 21.5 20.5 19.9 17.4 21.6 20.9 25.0 20.9 35.6 12.8 22.4 32.0 12.6 24.6 18.6 26.5 24.6 13.3 28.7 25.3 24.9 31.4 32.2 20.8 17.9 25.0 20.2 6.8 15.0 21.0 24.1 25.1 9.8 35.9 37.2 22.0 21.4 15.2 29.2 19.0 20.5 28.1 32.5 26.1 25.8 10.8 15.9 31.6 20.6 18.5 26.3 18.7 16.3 14.8 22.8 18.7 23.6 25.7 12.6 31.4 43.4 17.2 27.6 25.0 49.4 12.4 36.4 16.4 18.1 16.0 25.8 20.8 18.1 16.8 15.7 22.7 20.1 16.6 19.8 19.0 15.6 18.6 11.2 7.2 7.2 7.9 8.0 7.4 7.2 7.1 7.3 7.1 7.3 7.4 8.0 20.7 16.0 13.4 15.3 30.2 14.8 29.0 19.9 24.5 13.5 12.1 11.0 14.3 2.8 16.3 18.4 14.6 25.8 23.5 10.6 45.0 19.1 2.3 15.8 19.0 21.1 8.4 16.6 23.8 9.9 17.8 19.9 23.4 12.0 22.8 20.7 12.5 9.2 13.3 10.1 27.0 10.7 16.2 11.0 13.3 2.9 10.8 13.3 7.2 23.4 20.3 17.1 18.6 23.6 34.7 10.6 9.2 8.6 30.7 30.9 11.0 32.7 11.4 15.7 0.0 14.9 17.4 20.8 17.9 23.4 13.1 28.3 22.0 24.7 13.5 23.9 TSPAN31 SAS ENSG00000135452 "Tetraspanin 31" Q12999 12 57738013-57750219 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "glioma: 54.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 139.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030758, HPA057489" Approved Approved "Nucleoplasm,Golgi apparatus,Cytokinetic bridge,Cytosol" Yes No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 5: Muller glia cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Cytokinetic bridge, Cytosol" "HPA030758: , HPA057489: AB_2683447" "unprognostic (2.66e-2)" "unprognostic (1.50e-1)" "unprognostic (1.91e-1)" "unprognostic (1.82e-1)" "unprognostic (8.96e-3)" "prognostic unfavorable (1.09e-4)" "unprognostic (4.31e-3)" "unprognostic (1.19e-1)" "unprognostic (6.51e-3)" "unprognostic (5.31e-2)" "unprognostic (2.68e-1)" "unprognostic (2.79e-1)" "prognostic favorable (9.91e-5)" "unprognostic (1.68e-1)" "unprognostic (1.59e-1)" "unprognostic (6.32e-2)" "unprognostic (1.58e-1)" 24.5 29.7 9.0 11.2 10.8 5.5 23.1 10.8 15.6 26.2 11.8 20.5 16.4 26.2 13.2 20.4 25.8 20.9 26.7 9.5 10.3 26.7 20.9 22.8 11.8 11.2 10.2 25.6 25.2 32.7 24.4 12.5 11.0 22.1 10.7 29.7 25.6 13.5 21.0 18.6 18.5 8.4 11.1 20.8 23.0 8.0 9.9 9.8 30.2 21.2 8.7 21.0 20.1 13.0 9.5 23.4 21.1 5.4 44.3 24.0 13.5 15.8 11.7 4.6 5.1 16.7 46.4 7.6 32.7 29.0 9.4 17.5 5.7 26.7 10.7 23.1 15.4 10.7 18.7 6.6 45.2 10.6 17.9 29.6 30.2 13.7 30.3 22.1 14.6 4.6 7.5 19.9 19.6 19.4 9.2 5.9 4.3 18.3 7.0 10.5 139.8 20.0 15.7 19.0 6.6 16.7 15.6 21.3 10.5 4.5 41.1 15.8 27.6 11.3 9.5 5.6 7.4 28.9 8.1 4.1 32.7 6.3 19.2 25.4 26.3 16.4 35.8 28.6 34.8 31.1 28.5 30.7 27.6 31.0 28.3 26.2 5.8 35.4 42.0 58.3 22.1 33.0 9.0 10.8 10.8 15.6 9.5 10.3 11.2 10.2 11.0 11.1 9.9 13.0 37.1 48.1 32.4 8.1 23.8 11.2 46.4 37.4 22.2 43.2 32.0 27.4 5.1 20.0 31.4 31.3 41.7 20.9 29.8 19.9 9.8 37.6 1.2 18.5 32.5 26.7 26.5 8.2 9.1 39.0 15.2 31.7 11.7 20.4 45.0 28.9 22.1 21.6 22.4 21.9 9.1 21.6 32.6 18.0 16.4 1.8 25.7 24.2 32.0 8.4 21.6 62.7 35.0 11.1 13.3 37.6 20.3 17.3 18.4 30.5 30.6 18.1 27.9 60.4 19.7 22.3 31.9 9.2 7.7 16.1 12.6 24.5 20.4 35.3 19.4 31.8 TTC28 KIAA1043 ENSG00000100154 "Tetratricopeptide repeat domain 28" Q96AY4 22 27978014-28679865 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Astrocytes: 291.5;Excitatory neurons: 169.6;Inhibitory neurons: 289.8;Microglial cells: 332.6;Oligodendrocyte precursor cells: 318.7;Oligodendrocytes: 116.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001080 Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Microtubules, Cytokinetic bridge, Mitotic spindle" Cytosol "HPA001080: " "unprognostic (9.56e-2)" "unprognostic (1.17e-1)" "unprognostic (2.98e-1)" "unprognostic (8.55e-3)" "unprognostic (4.83e-2)" "unprognostic (5.20e-2)" "unprognostic (2.25e-1)" "prognostic favorable (4.30e-4)" "unprognostic (3.91e-2)" "unprognostic (1.18e-2)" "unprognostic (5.40e-2)" "unprognostic (5.10e-2)" "prognostic favorable (5.65e-5)" "unprognostic (5.54e-3)" "unprognostic (1.85e-1)" "prognostic unfavorable (1.21e-4)" "unprognostic (4.36e-1)" 7.2 4.6 4.3 2.9 3.0 0.8 6.3 0.4 3.4 8.8 2.6 6.9 3.1 10.2 9.8 5.2 8.7 6.4 4.9 3.9 1.8 4.9 3.5 7.2 2.0 2.4 2.0 16.8 5.0 3.8 3.8 8.8 1.4 5.1 2.9 3.4 6.8 6.9 5.4 3.0 3.8 8.5 1.8 3.5 4.8 8.1 2.1 2.7 6.8 5.1 1.4 6.3 5.0 2.1 0.0 6.8 17.1 7.4 10.0 14.8 0.3 5.1 9.4 7.1 6.1 0.5 0.0 0.1 6.9 14.9 2.3 1.0 11.1 0.3 3.8 0.7 7.5 1.1 8.6 6.5 4.5 0.2 6.8 14.9 0.3 4.6 3.2 4.8 13.0 4.5 4.5 0.6 1.6 2.5 0.1 0.6 3.1 0.0 4.3 7.0 4.3 0.1 3.3 0.2 4.8 10.6 7.1 0.2 4.5 4.7 3.5 0.6 12.2 8.4 4.0 5.5 3.8 2.2 0.2 0.1 3.0 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 4.3 3.0 0.4 3.4 3.9 1.8 2.4 2.0 1.4 1.8 2.1 2.1 29.4 3.2 12.5 291.5 3.2 6.0 5.8 1.7 11.4 34.1 8.7 8.0 9.7 8.6 1.6 12.9 18.8 6.0 2.3 2.1 0.0 6.2 10.8 7.9 28.9 30.9 9.0 7.0 169.6 6.0 1.5 27.3 4.1 12.4 1.3 32.3 36.8 15.3 3.7 28.6 289.8 5.8 0.0 9.4 7.2 9.1 31.4 4.3 10.6 332.6 0.7 11.5 5.2 318.7 116.3 3.9 4.4 45.5 3.1 5.0 4.8 18.6 1.9 24.9 13.1 27.2 19.7 23.8 11.6 6.7 3.8 2.5 3.2 27.4 6.9 4.0 TUBB "M40, MGC16435, OK/SW-cl.56, Tubb5" ENSG00000196230 "Tubulin beta class I" P07437 6 30717435-30725538 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 2296.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005417, CAB012406, HPA043640, HPA046280" Enhanced Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes 170000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB005417: AB_2241191, CAB012406: AB_2210370, HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (1.01e-1)" "unprognostic (2.33e-1)" "unprognostic (2.17e-3)" "unprognostic (1.92e-2)" "unprognostic (1.56e-1)" "unprognostic (2.16e-2)" "prognostic unfavorable (5.97e-4)" "unprognostic (2.57e-2)" "unprognostic (2.52e-1)" "unprognostic (2.18e-3)" "unprognostic (1.27e-2)" "unprognostic (2.47e-1)" "prognostic unfavorable (2.62e-8)" "unprognostic (8.63e-2)" "unprognostic (1.47e-1)" "unprognostic (2.49e-1)" "unprognostic (2.50e-1)" 229.5 164.8 74.6 243.5 81.8 541.0 186.9 46.2 367.7 228.7 87.0 250.3 87.6 333.0 174.5 246.3 227.0 158.5 245.3 73.5 119.7 137.8 236.6 205.3 369.2 80.5 74.8 467.5 138.1 74.4 97.0 194.4 99.2 145.2 194.4 82.4 160.2 194.6 185.7 211.9 159.4 371.0 57.5 195.0 172.8 77.8 94.0 620.4 142.4 98.6 487.6 222.3 213.8 63.5 2281.7 1027.3 2650.0 1458.4 733.2 1265.2 568.2 396.9 469.5 943.3 863.5 1329.2 703.9 1494.1 1105.1 1408.1 1877.8 805.3 2160.6 1968.0 160.3 892.5 1321.1 461.4 207.3 1306.7 345.8 2550.0 1223.9 943.6 455.9 416.0 443.6 967.1 1493.3 2058.1 1270.4 294.1 1844.8 1398.2 2719.0 249.3 377.3 604.1 948.6 102.6 708.5 911.6 1564.5 1071.4 940.8 1516.7 969.0 911.2 354.7 1625.5 1148.3 422.4 880.6 2712.0 1526.0 614.5 917.7 835.3 1735.4 2101.3 538.8 2494.6 3548.7 119.8 115.6 122.8 187.3 182.5 218.8 166.1 152.3 188.8 111.7 113.0 143.2 163.3 46.8 165.1 222.4 227.7 180.8 342.5 74.6 81.8 46.2 367.7 73.5 119.7 80.5 74.8 99.2 57.5 94.0 63.5 215.8 131.4 47.3 21.5 214.9 576.2 358.4 698.6 434.2 72.7 234.2 312.8 114.9 244.5 238.7 171.0 39.6 811.9 198.7 133.4 311.0 1091.0 9.1 69.1 261.6 370.8 163.6 1322.1 28.2 1061.1 2296.1 471.5 95.3 140.2 207.3 643.6 298.4 267.8 955.2 109.4 25.0 185.3 376.4 454.5 689.6 24.4 402.6 295.8 321.9 30.9 774.0 192.6 246.1 20.1 23.0 1087.0 90.7 237.3 304.6 199.5 117.9 245.9 66.6 65.4 118.3 124.0 838.6 58.0 126.5 447.0 430.6 220.4 244.0 224.9 253.2 229.0 TUBB1 dJ543J19.4 ENSG00000101162 "Tubulin beta 1 class VI" Q9H4B7 20 59019429-59026654 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.5;lymphoid tissue: 4.3" "Cell type enriched" "Detected in some" 10 "Macrophages: 191.2" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 17 "basophil: 63.5;neutrophil: 26.0" "Lineage enriched" "Detected in many" 24 "granulocytes: 63.5" "Cell line enriched" "Detected in some" 19 "HEL: 29.5" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004286, HPA043640, HPA046280" Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA 87000000 "Cluster 34: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB004286: AB_2288090, HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (3.76e-1)" "unprognostic (2.69e-1)" "unprognostic (6.10e-4)" "unprognostic (1.02e-1)" "unprognostic (5.00e-2)" "unprognostic (2.02e-1)" "unprognostic (5.86e-2)" "unprognostic (7.51e-4)" "unprognostic (1.90e-2)" "unprognostic (2.63e-1)" "unprognostic (6.80e-5)" "unprognostic (3.46e-1)" "unprognostic (1.16e-1)" "unprognostic (2.55e-1)" "unprognostic (1.40e-1)" "unprognostic (2.31e-1)" "unprognostic (1.00e-1)" 0.2 0.2 0.2 0.3 0.2 8.5 0.1 0.5 0.5 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.3 0.1 0.1 0.2 0.1 0.3 2.4 0.2 0.3 0.2 0.1 0.1 0.0 0.3 1.1 0.2 0.0 0.0 0.2 0.1 0.0 0.4 0.1 0.2 0.0 0.1 4.3 0.1 0.9 0.2 0.0 0.2 1.5 0.0 0.0 0.0 0.3 0.1 0.3 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.2 0.4 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.2 29.5 0.8 1.5 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.3 1.4 0.0 0.0 0.1 0.3 0.3 0.0 0.1 0.4 0.2 0.1 0.3 0.0 0.3 0.3 0.2 0.2 0.6 0.1 0.1 0.1 0.2 0.0 0.2 0.2 0.3 0.1 0.2 0.3 0.2 0.1 0.2 0.4 63.5 2.4 1.9 0.5 0.6 0.4 0.9 0.2 0.0 1.1 0.5 0.4 0.0 26.0 0.2 0.3 2.6 0.5 281.6 0.2 0.2 0.5 0.5 0.1 0.2 0.3 0.2 0.2 0.1 0.2 0.3 0.1 0.0 1.1 0.3 1.4 0.0 0.0 0.0 0.0 1.7 0.1 0.1 0.1 0.0 0.6 0.0 4.2 0.0 3.1 0.0 0.0 0.0 16.0 0.3 0.2 1.5 0.0 19.0 0.2 0.0 0.1 0.1 0.0 0.7 1.3 0.0 3.6 0.2 0.3 0.0 0.2 0.0 0.0 2.8 0.0 5.9 0.3 191.2 0.0 0.0 13.8 0.2 13.4 0.0 0.1 0.0 0.0 0.4 0.4 0.0 0.0 0.1 0.0 1.9 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.1 1.0 0.1 0.1 0.1 TUBB2A "dJ40E16.7, TUBB, TUBB2" ENSG00000137267 "Tubulin beta 2A class IIa" Q13885 6 3153497-3157544 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 364.3" "Cell type enhanced" "Detected in many" "Horizontal cells: 516.5;Suprabasal keratinocytes: 368.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 3.2;monocytes: 1.6;T-cells: 3.2" "Cell line enhanced" "Detected in all" "AF22: 241.1;CACO-2: 247.6;SuSa: 365.5;WM-115: 280.1" "Low region specificity" "Detected in all" "CAB015339, HPA043640, HPA046280" Supported Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 61: Squamous epithelial cells - Keratinization" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB015339: AB_2210539, HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (2.57e-1)" "unprognostic (9.86e-3)" "unprognostic (5.90e-3)" "unprognostic (7.98e-3)" "unprognostic (4.02e-3)" "unprognostic (1.67e-1)" "unprognostic (1.82e-3)" "unprognostic (7.53e-2)" "unprognostic (1.48e-3)" "unprognostic (9.99e-2)" "unprognostic (1.24e-2)" "unprognostic (1.42e-2)" "prognostic favorable (4.65e-4)" "unprognostic (2.39e-2)" "unprognostic (1.79e-1)" "unprognostic (3.10e-2)" "prognostic unfavorable (1.61e-4)" 58.8 17.8 266.1 19.3 251.1 67.5 47.8 130.1 287.5 32.7 10.0 78.0 24.2 50.8 28.0 90.6 23.5 21.5 29.4 248.3 364.3 31.1 67.0 16.4 11.0 292.6 212.2 15.5 39.4 2.2 56.3 23.9 334.3 17.5 8.2 49.9 52.2 15.6 22.3 151.4 34.9 41.7 131.6 7.7 41.0 9.5 204.4 6.4 10.0 11.8 9.6 23.6 51.2 169.4 55.9 45.3 241.1 53.6 30.6 34.0 14.5 119.8 44.7 80.6 115.7 247.6 18.4 27.4 72.9 115.5 80.2 26.0 86.6 26.8 28.0 134.1 57.7 9.4 11.4 77.0 31.6 1.5 8.4 35.1 31.1 85.1 5.3 28.9 37.3 10.6 33.7 8.8 74.2 25.1 14.9 2.8 207.2 16.0 58.3 12.4 22.6 18.9 28.0 27.4 57.6 52.9 30.5 8.5 179.7 365.5 19.1 2.0 76.0 53.9 56.7 117.3 65.8 3.2 4.6 18.8 19.7 7.0 280.1 0.0 1.1 0.0 2.2 1.6 2.4 3.2 2.1 3.1 0.5 0.6 1.0 2.0 0.3 0.4 1.3 0.2 3.2 1.2 266.1 251.1 130.1 287.5 248.3 364.3 292.6 212.2 334.3 131.6 204.4 169.4 125.3 16.0 13.1 43.1 31.6 311.4 63.3 87.0 132.6 105.6 32.0 134.6 20.4 42.9 62.7 12.9 16.7 6.0 53.4 87.0 217.2 54.0 60.9 46.7 29.6 40.6 73.1 322.3 59.9 182.4 50.4 96.2 185.0 57.9 34.9 10.1 12.5 55.6 50.8 516.5 73.0 103.9 73.2 6.3 164.4 32.9 20.8 36.7 129.9 24.4 72.7 261.0 0.0 18.1 23.0 103.4 181.8 15.4 15.8 34.9 126.3 40.4 50.3 86.2 6.6 95.6 87.9 32.4 14.9 140.6 368.5 6.2 58.9 6.4 60.0 54.7 TUBB2B "bA506K6.1, DKFZp566F223, MGC8685" ENSG00000137285 "Tubulin beta 2B class IIb" Q9BVA1 6 3223324-3231730 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 387.9;choroid plexus: 154.0" "Group enriched" "Detected in many" 4 "Distal tubular cells: 414.8;Horizontal cells: 430.7;Muller glia cells: 847.3;Skeletal myocytes: 350.1" "Cancer enriched" "Detected in many" 9 "glioma: 216.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 541.9;CACO-2: 415.3;NTERA-2: 268.0;RPMI-8226: 277.7;SCLC-21H: 797.7;SH-SY5Y: 390.2;SuSa: 245.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043640, HPA046280" Supported Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 43: B-cells - Humoral immune response" "Cluster 70: Brain - Nervous system development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 5: Muller glia cells - Visual perception" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (2.66e-2)" "unprognostic (3.41e-1)" "unprognostic (5.92e-3)" "prognostic unfavorable (1.94e-4)" "unprognostic (6.81e-2)" "unprognostic (3.26e-2)" "unprognostic (9.03e-3)" "unprognostic (8.33e-2)" "unprognostic (1.08e-1)" "unprognostic (2.02e-1)" "unprognostic (3.78e-3)" "unprognostic (3.34e-2)" "unprognostic (2.03e-2)" "unprognostic (6.24e-3)" "unprognostic (6.04e-2)" "unprognostic (3.58e-4)" "unprognostic (2.30e-3)" 4.0 7.2 298.1 8.1 324.5 1.0 5.0 348.4 387.9 9.9 154.0 17.0 2.4 4.2 45.5 2.4 3.3 3.8 4.6 258.8 356.9 11.6 1.0 1.4 8.1 363.3 349.9 1.1 5.7 0.0 35.1 4.4 354.5 3.7 2.6 65.3 10.8 4.6 6.2 3.9 6.1 7.3 337.2 0.7 4.5 1.0 369.1 2.3 0.9 1.6 5.7 2.6 5.6 383.9 0.0 8.2 541.9 164.2 0.6 0.2 0.9 5.1 7.4 20.8 45.0 415.3 2.0 0.9 5.6 5.7 0.0 1.3 212.8 0.7 12.0 1.6 98.3 0.2 0.0 33.2 1.1 0.1 6.1 3.1 0.0 2.3 0.0 7.6 1.4 0.5 6.8 1.2 7.6 0.3 1.5 0.4 268.0 1.0 17.6 0.6 26.3 277.7 2.9 0.8 797.7 390.2 0.3 1.7 4.3 245.9 3.2 0.0 0.0 1.9 89.9 6.3 2.2 51.6 0.1 0.0 0.8 0.1 30.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 298.1 324.5 348.4 387.9 258.8 356.9 363.3 349.9 354.5 337.2 369.1 383.9 3.6 0.0 0.0 109.4 1.9 8.7 2.3 1.8 4.6 63.5 3.9 31.9 40.1 5.7 0.3 7.3 16.7 0.7 1.0 0.9 414.8 15.4 5.8 2.7 3.3 7.6 66.7 0.0 2.4 3.5 1.2 18.7 7.1 3.9 0.0 0.5 0.7 0.6 3.0 430.7 19.4 1.0 24.4 0.0 12.4 7.1 0.3 1.0 92.5 9.4 3.6 847.3 0.0 37.2 21.6 12.0 0.1 0.0 8.4 3.9 0.2 2.0 0.0 43.1 0.0 350.1 19.1 1.3 6.2 3.1 2.7 0.8 0.6 0.0 0.6 1.1 TUBB3 "beta-4, CFEOM3, CFEOM3A, FEOM3" ENSG00000258947 "Tubulin beta 3 class III" Q13509 16 89921392-89938761 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 313.3" "Cell type enhanced" "Detected in some" "Astrocytes: 20.2;Ductal cells: 28.7;Excitatory neurons: 37.9;Exocrine glandular cells: 21.4;Gastric mucus-secreting cells: 27.0;Inhibitory neurons: 45.1;Pancreatic endocrine cells: 49.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "naive B-cell: 2.5" "Lineage enriched" "Detected in single" 9 "B-cells: 2.5" "Cell line enhanced" "Detected in many" "A549: 421.3;SCLC-21H: 424.9;SH-SY5Y: 433.8" "Low region specificity" "Detected in all" "HPA043640, HPA046280" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA 89000000 "Cluster 24: B-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (7.08e-2)" "unprognostic (3.37e-4)" "unprognostic (1.05e-1)" "unprognostic (1.06e-1)" "unprognostic (8.01e-2)" "unprognostic (3.12e-2)" "unprognostic (4.04e-3)" "unprognostic (1.12e-3)" "unprognostic (1.22e-2)" "unprognostic (6.06e-2)" "unprognostic (1.99e-2)" "unprognostic (1.38e-2)" "unprognostic (7.57e-2)" "unprognostic (1.27e-3)" "unprognostic (3.70e-2)" "unprognostic (3.05e-1)" "unprognostic (1.91e-2)" 5.7 24.8 99.4 12.1 93.3 3.4 2.1 100.5 127.6 3.3 0.0 18.4 3.7 9.7 0.2 3.6 2.3 8.8 5.5 88.6 313.3 13.3 0.9 4.1 7.1 208.8 132.7 3.9 3.2 0.4 55.1 1.8 266.2 3.0 2.6 24.8 10.6 0.4 0.6 5.2 8.0 12.7 74.2 1.3 7.2 38.0 183.4 1.0 2.5 0.3 5.2 7.3 5.3 82.5 30.1 421.3 152.6 173.9 17.9 170.8 6.8 181.0 31.0 105.8 48.2 57.2 53.5 89.6 93.6 136.8 74.3 112.1 148.9 26.7 26.3 22.7 15.5 0.7 32.5 383.7 6.0 0.0 67.6 98.4 7.9 161.9 14.0 136.8 88.4 5.9 9.2 2.5 122.3 288.6 1.2 31.5 274.3 11.2 237.3 0.1 54.1 9.5 131.8 8.1 424.9 433.8 251.2 4.4 137.1 27.5 15.0 1.9 110.9 142.8 156.9 197.3 185.3 1.4 19.6 35.2 150.2 11.5 260.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 99.4 93.3 100.5 127.6 88.6 313.3 208.8 132.7 266.2 74.2 183.4 82.5 0.4 0.0 0.0 20.2 0.0 0.0 0.0 0.0 3.4 1.8 0.2 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.1 0.0 28.7 8.2 0.5 2.6 3.8 4.9 0.0 37.9 21.4 0.7 6.1 27.0 0.7 0.0 0.0 0.0 0.0 0.2 5.0 45.1 0.1 0.0 0.0 0.0 16.8 0.3 0.2 0.0 9.4 0.0 0.3 0.0 16.1 9.2 49.2 0.0 0.4 0.4 0.0 0.0 0.1 0.0 1.4 0.0 0.0 5.1 0.2 0.4 3.0 0.0 1.0 0.1 0.0 0.2 0.0 TUBB4A "beta-5, DYT4, TUBB4" ENSG00000104833 "Tubulin beta 4A class IVa" P04350 19 6494319-6502848 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Dystonia, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 828.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 22.2;Muller glia cells: 33.0;Oligodendrocytes: 94.1;Theca cells: 81.7" "Group enriched" "Detected in many" 9 "glioma: 50.1;melanoma: 83.2;testis cancer: 49.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 13 "B-cells: 3.8;T-cells: 5.4" "Cell line enhanced" "Detected in many" "AN3-CA: 100.7;HAP1: 58.3;HEL: 91.7;PC-3: 49.6;REH: 43.4;SH-SY5Y: 36.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010768, HPA043640, HPA046280" Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA 110000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB010768: AB_261775, HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (4.05e-1)" "unprognostic (1.97e-1)" "unprognostic (2.72e-1)" "prognostic unfavorable (8.42e-7)" "unprognostic (3.07e-1)" "unprognostic (1.19e-1)" "unprognostic (2.11e-1)" "unprognostic (8.08e-2)" "unprognostic (6.69e-2)" "unprognostic (1.54e-1)" "unprognostic (1.11e-1)" "unprognostic (3.46e-2)" "unprognostic (1.12e-3)" "unprognostic (1.36e-2)" "unprognostic (1.58e-1)" "unprognostic (2.06e-1)" "unprognostic (2.30e-1)" 0.9 203.4 209.7 1.7 404.6 0.2 0.6 452.3 388.7 0.6 0.0 6.3 1.1 0.6 0.3 0.7 0.9 0.6 2.5 249.2 229.1 2.2 1.2 0.6 1.1 425.9 254.4 1.5 3.0 0.6 4.0 0.7 440.0 0.8 0.8 22.6 1.2 0.4 4.4 5.2 3.0 0.8 221.4 9.5 2.1 76.0 373.5 0.3 0.6 1.0 0.7 0.6 1.8 828.2 0.2 28.3 0.1 100.7 0.2 0.0 0.2 0.7 0.0 0.1 0.0 1.4 0.4 0.1 30.3 0.0 3.5 0.7 58.3 0.0 0.6 0.0 10.7 91.7 1.9 0.9 0.0 0.0 5.5 0.0 0.0 2.3 0.0 1.0 0.0 17.1 8.6 0.8 0.0 3.0 18.1 4.1 7.5 0.0 49.6 43.4 0.1 20.3 10.9 0.1 0.2 36.6 0.3 0.2 30.9 2.7 0.8 1.9 0.0 0.2 12.2 0.1 0.4 2.4 1.7 11.7 1.1 0.1 0.5 0.0 0.0 0.0 5.4 0.0 3.3 3.8 0.7 5.0 0.0 1.1 1.6 3.8 0.1 0.3 0.0 0.0 0.0 1.4 209.7 404.6 452.3 388.7 249.2 229.1 425.9 254.4 440.0 221.4 373.5 828.2 0.1 0.0 0.0 6.8 3.2 1.9 0.7 0.3 0.0 2.8 0.1 0.1 9.8 1.5 0.0 0.0 0.0 0.2 1.6 0.1 5.9 1.6 2.9 0.1 0.2 1.2 0.0 2.1 22.2 0.0 0.2 1.8 0.0 0.1 0.0 16.3 1.4 0.3 0.4 10.1 15.0 0.0 0.0 0.0 1.2 9.4 5.3 0.3 14.2 13.1 0.0 33.0 1.0 8.5 94.1 0.1 0.0 0.4 0.9 0.2 0.0 1.8 0.5 2.3 6.6 0.4 4.6 1.9 1.1 0.0 1.6 0.1 3.8 81.7 0.0 0.2 TUBB4B "Beta2, TUBB2C" ENSG00000188229 "Tubulin beta 4B class IVb" P68371 9 137241287-137243707 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Deafness, Disease variant, FDA approved drug targets, Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 2190.0;Late spermatids: 2907.1;Spermatocytes: 1717.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010880, HPA043640, HPA046280" Enhanced Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 38: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB010880: AB_609915, HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (2.24e-1)" "unprognostic (1.77e-3)" "unprognostic (1.50e-1)" "prognostic favorable (4.91e-4)" "unprognostic (1.29e-2)" "unprognostic (8.93e-2)" "prognostic unfavorable (9.98e-4)" "unprognostic (9.92e-3)" "unprognostic (2.90e-1)" "unprognostic (3.63e-1)" "unprognostic (2.34e-1)" "unprognostic (4.09e-2)" "unprognostic (2.47e-3)" "unprognostic (6.37e-2)" "unprognostic (1.36e-2)" "prognostic favorable (6.36e-6)" "unprognostic (1.69e-1)" 134.5 112.6 162.0 97.2 163.4 423.9 94.4 149.4 182.7 88.1 482.7 198.3 142.0 107.7 209.1 343.3 507.2 106.0 435.8 174.0 185.2 122.5 140.1 130.5 95.5 184.1 233.6 72.9 123.8 87.8 118.0 86.3 213.9 120.2 111.9 261.8 177.9 121.5 202.5 240.0 166.4 119.8 162.9 85.6 161.4 765.7 192.6 162.9 115.7 96.6 119.7 188.3 139.4 133.9 706.2 1032.5 431.7 314.2 213.2 223.6 600.5 643.7 536.0 872.4 598.6 1101.0 840.2 429.0 480.2 631.2 848.2 1305.1 539.5 1039.2 330.2 307.9 458.5 311.2 789.6 877.8 134.5 370.0 331.5 145.0 291.5 667.5 183.1 215.7 631.7 300.6 443.0 239.7 731.2 1936.4 337.4 504.2 457.8 1234.8 1778.1 423.5 822.2 394.2 666.8 647.8 301.5 323.6 853.9 485.8 173.2 244.2 699.0 397.6 495.6 618.1 685.0 710.0 863.6 92.4 274.9 475.1 503.6 286.9 549.8 95.7 30.0 43.2 40.5 30.1 38.2 32.6 31.3 34.4 34.9 30.8 19.7 26.7 56.4 24.4 30.5 36.3 44.7 32.6 162.0 163.4 149.4 182.7 174.0 185.2 184.1 233.6 213.9 162.9 192.6 133.9 478.5 221.2 146.3 21.5 315.8 326.2 945.7 458.7 327.2 508.1 286.9 389.5 91.9 143.0 284.1 143.5 300.3 346.6 640.9 744.1 221.1 348.6 2190.0 1191.6 224.8 203.9 391.5 419.9 30.1 446.8 545.5 247.8 274.7 415.0 189.2 200.9 142.5 139.2 265.9 244.0 24.3 503.6 323.5 59.9 214.9 2907.1 254.2 299.3 138.7 22.5 224.0 299.3 49.4 15.6 19.7 477.4 697.2 153.1 264.0 475.1 540.7 345.5 1558.7 763.3 111.7 261.8 416.0 1717.5 740.9 419.1 297.6 321.1 362.9 89.8 487.3 592.7 TUBB6 "HsT1601, MGC4083" ENSG00000176014 "Tubulin beta 6 class V" Q9BUF5 18 12307669-12344320 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 190.2;Extravillous trophoblasts: 494.3;Pancreatic endocrine cells: 221.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 157.3" "Group enriched" "Detected in many" 6 "B-cells: 58.7;dendritic cells: 157.3" "Cell line enhanced" "Detected in many" "TIME: 821.6" "Region enriched" "Detected in many" 6 "olfactory bulb: 19.9" "Region enhanced" "Detected in all" "spinal cord: 10.3" "HPA043640, HPA046280" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes 52000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (4.40e-2)" "unprognostic (8.28e-3)" "unprognostic (1.22e-2)" "unprognostic (5.20e-3)" "unprognostic (8.42e-2)" "unprognostic (3.37e-3)" "unprognostic (1.17e-1)" "unprognostic (2.74e-2)" "unprognostic (4.95e-2)" "unprognostic (4.90e-2)" "unprognostic (1.06e-1)" "unprognostic (4.25e-2)" "prognostic unfavorable (1.22e-7)" "unprognostic (5.83e-3)" "unprognostic (1.99e-1)" "unprognostic (4.94e-2)" "prognostic unfavorable (9.69e-4)" 197.9 37.9 12.3 82.1 11.7 34.8 134.6 14.7 14.6 106.5 28.6 193.6 31.4 173.5 24.9 217.5 121.2 66.4 166.2 11.8 13.7 66.0 40.8 92.9 31.6 19.2 16.3 81.2 52.7 5.6 33.1 59.7 15.1 84.2 28.8 3.6 69.6 91.3 37.3 78.2 75.8 151.9 14.1 34.0 89.1 28.3 18.4 12.2 52.2 20.2 31.3 129.9 124.2 12.5 211.8 142.3 149.5 76.1 149.0 208.8 108.1 648.5 424.2 492.0 459.1 113.0 65.2 1.3 281.7 440.8 148.6 99.5 84.7 653.6 380.6 1.8 46.1 32.3 159.2 73.6 151.0 2.7 59.5 219.1 146.0 429.4 222.7 148.8 366.1 12.5 159.7 2.5 432.5 216.1 0.8 162.4 79.1 3.3 70.0 1.6 260.0 2.2 99.7 5.8 19.3 27.2 360.3 34.8 113.9 153.7 76.5 203.8 821.6 600.0 510.6 565.7 574.2 11.5 3.8 3.8 458.9 46.9 219.8 2.0 19.4 0.3 0.6 7.6 0.3 42.0 0.1 0.2 25.5 58.7 0.2 0.3 0.4 0.9 7.5 157.3 0.2 13.2 12.3 11.7 14.7 14.6 11.8 13.7 19.2 16.3 15.1 14.1 18.4 12.5 67.0 83.3 7.9 0.7 16.1 69.6 42.7 151.4 16.5 1.2 30.4 44.8 54.3 8.6 37.4 7.3 0.0 53.8 23.6 0.6 1.9 167.6 190.2 6.4 76.9 128.9 0.0 12.2 0.8 104.9 494.3 112.8 1.5 7.1 45.6 7.4 82.5 0.4 69.4 0.0 0.6 0.4 42.7 13.2 85.2 114.9 70.2 36.5 33.8 12.2 65.9 0.2 0.0 0.5 0.4 221.1 0.1 91.4 1.0 51.5 0.1 1.2 18.2 1.6 26.3 89.2 130.5 4.3 6.3 55.7 66.9 22.2 3.6 9.5 0.5 65.2 TUBB8 bA631M21.2 ENSG00000261456 "Tubulin beta 8 class VIII" Q3ZCM7 10 46888-74163 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 2.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 3.4;Early spermatids: 11.7;Late spermatids: 3.4;Spermatocytes: 13.0;Spermatogonia: 15.9" "Cancer enriched" "Detected in single" 5 "testis cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "MCF7: 1.3" "HPA043640, HPA046280" Uncertain Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 49: Eosinophils - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (4.75e-2)" "unprognostic (6.02e-2)" "unprognostic (1.50e-1)" "unprognostic (2.82e-1)" "unprognostic (2.78e-1)" "unprognostic (1.80e-1)" "unprognostic (7.74e-2)" "unprognostic (8.33e-3)" "unprognostic (1.50e-1)" "unprognostic (4.15e-3)" "unprognostic (7.17e-2)" "unprognostic (3.30e-2)" "unprognostic (1.33e-3)" "unprognostic (4.53e-2)" "unprognostic (1.61e-1)" "unprognostic (2.19e-2)" "unprognostic (6.86e-3)" 0.1 0.1 0.4 0.1 0.4 0.0 0.2 0.3 0.6 0.2 0.2 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.3 0.3 0.7 0.0 0.1 0.1 0.3 0.3 0.4 0.3 0.3 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.3 0.1 2.4 0.3 0.0 0.7 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.3 0.6 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.0 0.0 0.3 0.1 0.0 0.7 0.0 0.0 0.0 0.2 0.1 3.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 11.7 0.4 0.1 0.1 0.0 0.0 0.7 0.0 0.2 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 3.4 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.7 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.5 13.0 15.9 0.0 0.0 0.0 0.0 0.4 0.0 0.6 TUBB8B TUBB8P12 ENSG00000173213 "Tubulin beta 8B" A6NNZ2 18 47390-49557 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "testis: 2.1" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "testis cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043640, HPA046280" Uncertain Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (4.34e-1)" "unprognostic (3.15e-2)" "unprognostic (1.29e-1)" "unprognostic (6.73e-2)" "unprognostic (1.76e-1)" "unprognostic (6.91e-2)" "unprognostic (1.92e-1)" "unprognostic (4.36e-2)" "unprognostic (1.29e-1)" "unprognostic (2.09e-1)" "unprognostic (4.46e-2)" "unprognostic (7.42e-4)" "unprognostic (3.96e-2)" "unprognostic (5.98e-2)" "unprognostic (4.88e-2)" "unprognostic (3.21e-2)" "unprognostic (1.78e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UBE2C UBCH10 ENSG00000175063 "Ubiquitin conjugating enzyme E2 C" O00762 20 45812576-45816957 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 78.5;lymphoid tissue: 113.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 129.6;Erythroid cells: 182.1;Extravillous trophoblasts: 449.1;Granulosa cells: 119.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 8.2" "Group enriched" "Detected in many" 5 "granulocytes: 2.1;NK-cells: 2.1;T-cells: 8.2" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 4.3;white matter: 11.4" "Low region specificity" "Detected in some" "CAB011464, HPA034569, CAB035990, HPA054975" Approved Approved "Plasma membrane,Cytosol" Yes Yes "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "CAB011464: AB_442965, CAB035990: , HPA034569: AB_2674226, HPA054975: AB_2682658" "unprognostic (1.45e-2)" "unprognostic (2.19e-1)" "unprognostic (1.06e-1)" "unprognostic (2.11e-3)" "unprognostic (2.54e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (6.24e-6)" "unprognostic (2.27e-3)" "unprognostic (2.59e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (6.91e-4)" "unprognostic (3.76e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.09e-1)" "unprognostic (3.61e-1)" "unprognostic (4.65e-2)" "unprognostic (2.68e-1)" 2.6 2.9 0.3 21.5 0.3 78.5 4.3 0.9 0.6 6.1 0.7 26.7 21.4 5.7 0.6 37.2 1.9 2.7 1.4 0.2 0.3 1.9 2.9 5.4 45.3 0.3 0.7 1.3 1.0 0.4 0.4 20.4 0.7 1.5 30.9 0.2 5.0 0.9 0.9 18.5 20.6 10.5 0.2 15.8 13.0 16.4 1.6 113.5 1.1 0.2 69.5 6.9 12.3 0.4 312.8 223.9 390.9 188.3 10.4 24.0 225.2 238.5 121.6 390.7 278.4 743.8 345.4 327.6 233.2 115.5 475.6 294.9 2.2 260.5 395.8 141.7 213.7 101.5 168.5 196.0 3.0 145.4 241.6 7.6 27.8 265.7 257.3 57.4 193.4 206.4 1.8 261.6 325.4 516.2 243.5 41.1 237.1 350.8 529.4 256.0 354.8 1.4 134.9 105.9 226.1 188.7 378.3 271.7 154.4 196.2 276.6 209.4 70.1 341.2 298.4 236.2 473.4 84.3 2.9 369.4 208.0 103.4 328.6 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.8 1.7 0.6 0.1 0.1 0.1 2.1 2.1 0.5 0.3 8.2 3.2 0.3 0.3 0.9 0.6 0.2 0.3 0.3 0.7 0.7 0.2 1.6 0.4 0.9 0.0 3.7 0.0 17.9 17.3 7.8 39.0 5.7 0.0 8.6 14.6 0.0 1.5 9.3 0.0 0.0 129.6 3.6 27.4 0.0 1.3 12.0 5.8 5.9 9.5 1.2 182.1 0.0 0.5 449.1 28.5 25.5 9.6 5.7 119.0 18.2 3.6 92.6 0.0 0.1 41.1 50.8 20.8 18.1 6.4 0.9 24.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.5 7.2 0.0 37.0 12.6 6.2 0.6 1.8 0.0 0.0 0.5 19.2 52.2 50.7 83.2 11.6 31.2 13.7 2.5 68.4 18.4 UBE2M "hUbc12, UBC12" ENSG00000130725 "Ubiquitin conjugating enzyme E2 M" P61081 19 58555712-58558954 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 1197.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004993, HPA054551, HPA057800" Approved Enhanced "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" Yes No 49000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nucleoli, Nuclear bodies, Cytosol" "CAB004993: AB_436983, HPA054551: AB_2682520, HPA057800: AB_2683531" "unprognostic (1.42e-1)" "unprognostic (1.99e-1)" "unprognostic (1.63e-2)" "unprognostic (1.39e-1)" "unprognostic (8.35e-2)" "unprognostic (1.77e-1)" "unprognostic (1.17e-3)" "unprognostic (3.90e-3)" "unprognostic (4.86e-2)" "unprognostic (1.09e-2)" "unprognostic (3.05e-3)" "unprognostic (1.96e-1)" "unprognostic (1.81e-1)" "unprognostic (8.63e-3)" "unprognostic (1.76e-1)" "unprognostic (5.85e-2)" "unprognostic (8.42e-3)" 46.3 66.1 133.2 39.2 138.8 82.2 42.8 116.7 199.7 48.9 104.0 72.5 41.7 48.1 36.3 61.8 51.3 30.9 111.0 141.2 129.3 63.2 45.6 46.3 43.4 123.5 124.4 46.0 47.5 84.5 69.7 45.0 127.7 48.3 32.5 49.7 48.5 46.1 174.0 56.6 41.6 39.5 111.9 49.3 55.8 81.0 124.4 51.7 44.3 104.5 43.7 58.3 45.8 139.1 161.8 272.1 119.3 124.8 61.7 71.9 112.2 166.0 117.4 97.8 82.8 162.7 109.7 161.9 135.5 93.4 198.1 105.9 130.1 138.6 69.2 207.3 1197.4 235.5 163.7 113.7 154.4 197.3 192.9 82.1 107.1 145.9 167.3 102.6 117.8 146.3 119.6 179.4 127.3 158.2 177.2 223.7 87.1 155.1 306.5 171.7 106.7 204.5 111.6 166.8 239.5 205.5 133.1 149.7 163.3 41.6 94.4 188.4 105.2 333.4 80.5 110.6 281.3 262.3 411.9 169.6 206.0 177.6 220.5 6.7 3.6 4.2 3.0 2.6 2.2 2.8 3.2 3.2 2.8 3.8 3.3 2.2 10.1 1.7 2.7 6.7 2.9 1.9 133.2 138.8 116.7 199.7 141.2 129.3 123.5 124.4 127.7 111.9 124.4 139.1 75.1 6.4 13.0 14.7 32.7 40.4 36.3 15.9 6.2 100.0 74.5 81.3 38.5 20.0 11.6 18.4 20.9 21.0 72.9 63.9 7.9 17.3 25.7 89.6 68.0 40.1 41.2 39.8 22.9 30.6 22.4 38.9 21.9 63.3 19.7 103.3 28.5 38.0 35.4 109.4 20.8 43.8 20.3 27.0 33.5 34.0 17.4 42.5 35.6 15.9 21.1 142.3 14.4 8.5 17.9 41.8 21.4 13.9 35.4 59.1 37.9 33.9 18.6 81.1 26.3 41.5 55.4 27.1 7.9 17.0 56.8 52.5 41.0 156.1 41.6 56.2 UGDH ENSG00000109814 "UDP-glucose 6-dehydrogenase" O60701 4 39498755-39528311 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" "Allosteric enzyme, Oxidoreductase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 137.7" "Cell type enhanced" "Detected in all" "Exocrine glandular cells: 345.5;Hepatocytes: 231.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 509.6;Hep G2: 595.9;U-2197: 375.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034444, HPA036656, HPA036657" Enhanced Supported Nucleoplasm Yes No 1300000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "CAB034444: AB_2019602, HPA036656: AB_10671706, HPA036657: AB_10672360" "unprognostic (1.22e-2)" "unprognostic (1.62e-1)" "unprognostic (2.73e-2)" "unprognostic (3.96e-2)" "unprognostic (5.54e-2)" "unprognostic (1.63e-1)" "unprognostic (8.78e-3)" "unprognostic (6.07e-2)" "unprognostic (1.34e-1)" "unprognostic (1.41e-1)" "unprognostic (9.81e-3)" "unprognostic (6.86e-2)" "prognostic unfavorable (5.51e-10)" "unprognostic (2.48e-1)" "unprognostic (2.04e-1)" "unprognostic (1.66e-1)" "unprognostic (4.97e-2)" 48.5 27.8 6.2 29.5 7.3 2.4 32.0 9.4 9.2 31.5 18.1 96.5 45.3 29.1 10.6 34.1 29.6 40.5 16.0 5.9 8.3 37.5 137.7 19.0 13.3 7.4 7.7 30.0 33.7 23.1 7.8 38.4 8.0 35.6 73.3 14.3 16.8 14.0 6.7 9.9 41.1 23.5 7.6 11.5 47.4 6.8 8.4 10.3 27.8 9.5 14.5 54.4 17.1 9.7 36.0 509.6 58.4 76.2 181.5 185.3 51.3 102.7 113.8 94.5 84.8 76.2 115.5 25.4 63.0 133.3 94.5 33.5 56.0 29.5 95.8 32.1 13.0 26.2 65.4 595.9 72.7 34.1 25.3 64.4 14.9 160.2 49.8 78.9 59.3 20.9 34.1 17.3 67.9 89.8 29.4 34.4 53.1 194.0 46.4 48.3 95.0 22.0 53.7 120.0 31.2 46.7 69.2 37.9 45.3 41.4 21.0 27.0 85.9 97.9 49.1 375.8 54.2 42.1 33.3 23.3 86.9 25.8 56.6 30.0 20.9 19.7 23.2 18.4 37.8 18.8 18.8 24.9 19.0 18.4 16.1 19.4 3.8 42.3 11.2 22.5 13.5 18.8 6.2 7.3 9.4 9.2 5.9 8.3 7.4 7.7 8.0 7.6 8.4 9.7 19.1 25.6 27.6 4.6 14.1 116.1 73.4 19.5 43.9 7.5 115.8 62.0 8.9 24.3 25.4 20.2 14.6 21.3 12.9 207.8 70.5 54.7 1.1 78.3 53.8 25.4 113.3 9.1 10.6 345.5 78.8 145.7 184.0 64.8 35.5 11.1 20.7 231.3 17.8 10.1 12.6 114.5 12.2 20.2 33.3 1.6 33.2 12.7 30.2 7.5 19.9 7.3 9.2 46.3 12.8 195.8 112.2 29.0 21.3 127.3 81.4 79.6 65.7 9.2 32.9 39.0 57.5 6.5 5.5 102.2 40.1 29.0 11.7 12.4 152.4 86.4 UGT3A2 ENSG00000168671 "UDP glycosyltransferase family 3 member A2" Q3SY77 5 36035021-36071358 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.5;lymphoid tissue: 14.7;skin 1: 10.3" "Group enriched" "Detected in some" 4 "Collecting duct cells: 3.7;Early spermatids: 4.4;Late spermatids: 8.2;Proximal tubular cells: 3.8" "Cancer enriched" "Detected in some" 5 "testis cancer: 4.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 6.8;JURKAT: 6.3;MOLT-4: 12.4;REH: 29.9;SuSa: 11.8;T-47d: 7.2;THP-1: 18.0" "Low region specificity" "Detected in many" HPA059475 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" Yes NA "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Golgi apparatus, Cytosol" "HPA059475: AB_2684031" "unprognostic (1.83e-4)" "unprognostic (9.94e-2)" "unprognostic (8.87e-2)" "unprognostic (4.82e-4)" "unprognostic (3.18e-1)" "unprognostic (3.52e-2)" "unprognostic (1.56e-1)" "unprognostic (6.08e-2)" "unprognostic (2.04e-1)" "unprognostic (8.13e-2)" "unprognostic (7.49e-2)" "unprognostic (4.17e-2)" "unprognostic (1.36e-3)" "unprognostic (6.65e-2)" "unprognostic (7.52e-2)" "unprognostic (7.38e-2)" "unprognostic (4.52e-3)" 0.0 0.8 0.0 0.0 0.0 6.5 1.1 0.3 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.3 2.6 0.6 0.0 0.0 1.0 1.1 0.0 0.0 0.1 0.9 0.2 1.2 0.4 0.0 0.1 0.1 0.0 0.1 10.3 0.0 0.0 0.1 1.2 0.1 2.9 0.6 14.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.6 1.8 0.0 0.1 0.0 0.0 0.3 0.4 0.0 1.3 0.0 0.5 6.8 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 12.4 0.0 5.3 0.0 0.0 29.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 7.2 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.3 1.0 1.1 1.2 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 3.7 0.0 0.2 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.7 0.0 0.0 0.0 0.1 0.0 0.7 0.1 0.0 0.1 0.0 0.0 0.0 1.1 8.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.3 0.1 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.3 0.0 0.1 0.0 0.0 UNC13B "hmunc13, Munc13-2, UNC13, Unc13h2" ENSG00000198722 "Unc-13 homolog B" O14795 9 35161992-35405338 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Alveolar cells type 2: 80.7;Cone photoreceptor cells: 95.9;Excitatory neurons: 60.4;Microglial cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024493, HPA062300" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles,Intermediate filaments" Yes No "Cluster 77: Retina - Visual perception" "Cluster 21: OE19 - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "Nucleoplasm, Golgi apparatus, Intermediate filaments" "HPA024493: AB_1858618, HPA062300: AB_2684742" "unprognostic (9.73e-3)" "unprognostic (2.33e-1)" "prognostic favorable (4.96e-4)" "unprognostic (6.56e-2)" "unprognostic (9.93e-2)" "prognostic favorable (8.51e-5)" "unprognostic (7.64e-2)" "prognostic favorable (6.59e-5)" "unprognostic (3.80e-1)" "unprognostic (1.64e-1)" "prognostic favorable (3.71e-4)" "unprognostic (1.74e-1)" "prognostic favorable (4.34e-11)" "unprognostic (2.40e-1)" "unprognostic (1.89e-1)" "unprognostic (1.48e-1)" "unprognostic (2.80e-2)" 12.6 12.8 10.5 5.6 13.3 1.0 10.3 6.6 14.5 12.5 15.7 22.2 11.6 10.1 7.7 17.5 10.4 11.5 13.6 11.4 7.2 21.8 12.8 38.9 1.8 8.3 9.5 7.3 21.3 15.0 11.5 6.0 7.8 22.6 25.0 41.2 17.8 23.3 24.2 12.3 13.4 11.9 7.3 4.7 17.9 15.6 10.6 3.0 12.2 10.4 5.0 10.2 12.7 9.0 9.8 12.8 13.9 22.6 26.3 14.6 11.8 15.7 7.1 11.4 15.3 10.7 4.5 0.0 7.0 20.6 20.1 4.7 35.4 18.2 14.5 0.0 11.3 5.9 36.6 13.9 12.7 2.2 6.4 11.6 14.0 18.0 18.5 18.2 37.3 15.8 13.5 8.1 13.5 7.5 2.1 0.2 12.6 30.2 13.3 0.1 8.6 3.4 15.5 12.6 14.9 15.7 11.0 6.8 11.4 23.0 11.6 7.5 34.5 7.8 7.2 12.3 12.2 12.7 16.2 0.0 8.5 18.4 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 13.3 6.6 14.5 11.4 7.2 8.3 9.5 7.8 7.3 10.6 9.0 6.7 57.7 80.7 28.7 0.8 3.1 1.1 2.1 3.4 42.3 7.3 4.4 11.4 18.6 16.7 9.2 95.9 3.7 0.1 24.4 3.9 6.0 6.9 8.2 5.1 8.5 24.6 1.7 60.4 12.2 2.1 4.8 16.3 13.9 2.5 8.7 5.7 12.5 4.9 6.7 17.7 31.9 0.0 2.4 3.0 12.3 2.1 3.7 7.2 73.1 0.1 5.7 0.0 42.3 36.7 7.8 11.9 3.0 4.2 11.7 10.5 7.8 10.0 40.8 6.6 8.4 6.5 8.7 7.5 14.3 7.4 2.9 1.0 5.7 19.5 5.7 URI1 "C19orf2, FLJ10575, NNX3, PPP1R19, RMP, URI" ENSG00000105176 "URI1 prefoldin like chaperone" O94763 19 29923644-30016612 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Protein phosphatase inhibitor, Repressor" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 499.7;Late spermatids: 514.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071709 Approved Supported Nucleoplasm,Cytosol Yes No "Cluster 24: B-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm Cytosol "HPA071709: AB_2686434" "unprognostic (4.22e-2)" "unprognostic (2.75e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (1.12e-4)" "unprognostic (2.96e-2)" "unprognostic (2.98e-1)" "unprognostic (1.40e-3)" "unprognostic (8.12e-2)" "unprognostic (1.26e-2)" "unprognostic (4.42e-3)" "unprognostic (1.57e-1)" "unprognostic (3.71e-1)" "unprognostic (1.33e-1)" "unprognostic (6.14e-2)" "unprognostic (1.23e-2)" "unprognostic (1.42e-1)" "unprognostic (4.47e-2)" 25.0 30.6 29.7 24.8 39.6 36.4 36.7 57.8 40.7 27.9 21.0 26.1 23.5 34.2 32.3 28.5 30.2 25.1 28.1 25.0 36.8 25.6 30.5 22.9 39.9 35.9 32.3 44.1 21.9 31.4 11.0 24.1 34.5 37.7 32.1 32.4 27.2 30.4 52.8 44.9 23.4 22.8 28.4 30.0 25.0 51.6 30.9 31.7 55.4 36.2 37.3 24.8 10.7 45.6 64.8 85.9 39.5 61.7 27.5 39.8 66.5 41.3 34.4 29.5 33.7 45.4 41.5 99.7 79.4 48.2 23.4 44.6 84.8 52.7 66.5 69.7 48.5 90.8 44.3 59.7 39.7 88.5 37.3 35.1 70.6 25.7 95.7 31.7 22.1 58.2 109.7 27.2 37.4 55.3 58.0 37.1 37.1 83.4 26.2 56.7 73.2 40.5 19.4 75.3 63.4 49.7 47.1 56.3 62.2 41.7 23.5 54.8 29.1 72.1 63.9 35.6 63.3 74.4 86.2 67.7 35.5 76.5 44.4 3.4 1.3 1.8 2.9 1.4 2.5 1.9 2.6 3.0 1.1 4.5 3.1 3.1 0.1 2.2 1.4 1.6 2.2 0.8 29.7 39.6 57.8 40.7 25.0 36.8 35.9 32.3 34.5 28.4 30.9 45.6 51.6 44.8 38.8 59.1 48.6 57.0 95.3 19.4 40.5 60.6 67.6 68.1 52.8 48.6 28.2 40.5 25.0 19.2 84.4 21.7 105.7 16.9 499.7 48.5 82.8 32.5 28.9 38.5 79.9 27.8 28.7 45.6 41.3 41.8 30.9 54.5 31.8 50.9 15.4 52.2 122.3 36.5 18.3 33.6 24.0 514.0 43.8 32.9 32.0 74.9 25.0 58.5 70.0 137.7 178.4 19.4 23.7 41.3 53.3 123.9 19.4 85.2 38.8 59.8 13.1 82.3 48.5 72.2 52.2 44.8 73.6 13.1 74.2 91.6 37.0 94.3 USP3 ENSG00000140455 "Ubiquitin specific peptidase 3" Q9Y6I4 15 63504511-63594640 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 36.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053275, HPA060513, HPA077975" Supported "Nucleoplasm,Midbody ring" "Intracellular and membrane" Yes No "Cluster 1: Neutrophils - Mixed function" "Cluster 50: Non-specific - Ribosome" "Cluster 15: RT4 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Midbody ring" "HPA053275: AB_2682096, HPA060513: AB_2684299, HPA077975: AB_2732365" "unprognostic (4.63e-3)" "unprognostic (2.71e-1)" "unprognostic (7.88e-2)" "unprognostic (3.33e-2)" "unprognostic (2.16e-2)" "unprognostic (6.03e-2)" "unprognostic (6.26e-2)" "unprognostic (4.52e-2)" "unprognostic (1.62e-2)" "unprognostic (2.36e-1)" "unprognostic (3.54e-2)" "unprognostic (4.87e-2)" "unprognostic (1.17e-1)" "unprognostic (8.61e-2)" "unprognostic (2.78e-1)" "unprognostic (6.21e-2)" "prognostic favorable (1.38e-4)" 12.7 8.2 5.8 5.4 7.0 21.4 11.2 36.4 5.9 11.7 15.4 13.4 6.5 12.9 4.7 10.9 10.9 5.4 6.0 5.3 6.3 10.1 8.2 13.2 6.5 6.9 6.9 16.2 18.9 3.1 6.2 2.7 7.6 10.4 5.6 6.3 12.4 6.0 10.0 14.6 13.9 4.5 5.3 17.6 15.7 5.3 8.6 7.4 9.1 3.6 6.4 12.4 11.9 7.5 10.4 21.0 12.1 8.1 5.5 7.6 8.2 6.7 9.6 7.1 5.8 6.6 13.1 8.7 15.3 9.3 3.6 12.0 11.6 11.1 5.6 12.2 5.8 10.4 8.6 9.8 6.8 6.4 11.4 11.3 7.8 7.7 10.6 8.9 12.4 17.3 9.5 9.0 3.3 5.2 11.0 8.8 16.2 13.7 5.3 22.2 8.4 11.3 4.5 23.8 9.6 9.5 3.3 13.0 6.7 7.8 5.5 9.5 13.4 7.2 16.9 3.3 10.3 9.3 24.4 18.2 7.4 13.8 7.5 120.0 84.7 12.7 24.8 66.0 28.4 34.1 34.3 26.0 59.8 34.8 34.0 25.2 169.1 19.8 65.4 13.1 28.1 45.2 5.8 7.0 36.4 5.9 5.3 6.3 6.9 6.9 7.6 5.3 8.6 7.5 23.6 38.5 69.2 76.7 63.4 52.6 34.3 24.8 23.3 31.4 27.9 20.3 9.2 25.8 41.4 16.5 12.5 19.8 48.4 37.6 41.1 41.0 21.6 37.8 32.8 26.0 43.8 15.8 11.2 37.2 57.3 28.3 39.8 74.6 27.1 64.5 11.4 24.0 24.8 13.5 40.0 35.4 30.5 78.4 109.6 77.4 15.8 74.5 42.7 75.9 101.8 25.9 41.2 80.4 40.6 39.8 35.6 18.4 69.7 40.6 33.2 28.3 33.3 17.9 13.1 25.3 34.5 14.8 40.3 33.9 59.0 34.1 64.6 40.1 40.6 37.6 UTP6 "C17orf40, HCA66" ENSG00000108651 "UTP6 small subunit processome component" Q9NYH9 17 31860904-31901708 "Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 102.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025936, HPA055806" Supported Enhanced "Nucleoli,Mitotic chromosome" Yes No "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 35: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoli "Mitotic chromosome" "HPA025936: AB_1845588, HPA055806: AB_2682930" "unprognostic (1.55e-1)" "unprognostic (1.07e-1)" "unprognostic (5.61e-3)" "unprognostic (2.54e-1)" "unprognostic (4.96e-2)" "unprognostic (1.11e-2)" "prognostic unfavorable (1.86e-5)" "unprognostic (5.68e-2)" "unprognostic (9.78e-3)" "unprognostic (5.50e-2)" "unprognostic (2.79e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (1.16e-6)" "unprognostic (1.63e-1)" "unprognostic (2.87e-1)" "unprognostic (3.96e-2)" "unprognostic (4.76e-2)" 17.7 14.3 24.2 7.8 24.3 9.5 15.8 24.9 39.8 21.5 25.4 17.0 4.4 15.3 12.9 17.7 17.1 4.3 17.2 24.2 24.1 21.1 24.4 14.5 11.4 24.0 24.3 20.5 19.1 5.1 19.7 6.4 24.0 22.3 6.4 10.2 13.1 5.7 16.2 17.4 17.1 6.9 23.6 25.7 15.1 18.7 24.5 9.1 18.0 6.3 12.5 16.7 17.0 24.7 14.4 9.0 12.3 7.4 11.9 8.0 15.3 11.8 6.7 17.6 13.6 32.8 7.8 20.9 14.0 11.3 16.7 18.6 16.7 14.1 16.0 4.6 26.4 13.1 21.2 31.6 14.1 19.8 13.5 13.2 15.1 16.7 12.5 16.3 11.4 13.2 23.1 11.9 13.8 11.6 19.4 56.4 16.9 17.2 14.6 20.6 17.8 21.4 19.0 12.9 8.4 12.8 12.5 9.3 22.7 19.4 22.7 39.0 11.5 27.8 20.5 14.3 24.3 13.0 25.9 31.8 18.9 14.4 15.4 15.5 10.6 7.4 7.1 11.3 7.0 12.6 7.7 7.7 14.7 15.2 6.6 7.7 13.7 5.9 11.1 21.3 8.1 7.8 24.2 24.3 24.9 39.8 24.2 24.1 24.0 24.3 24.0 23.6 24.5 24.7 22.5 19.2 24.3 17.9 32.7 25.7 30.7 29.1 12.5 16.7 13.5 16.3 15.6 14.3 31.7 5.5 8.4 42.4 34.3 10.6 9.8 29.7 35.6 23.4 29.0 21.1 5.4 29.5 23.0 24.0 50.3 26.2 16.3 33.5 36.2 20.5 12.1 15.6 35.8 11.8 21.4 16.3 20.3 21.0 17.6 5.4 18.6 29.4 8.8 18.7 43.4 16.4 7.2 17.6 16.2 26.3 8.4 17.0 17.4 31.9 12.7 18.5 30.3 16.4 6.6 28.2 23.7 102.9 66.2 17.2 26.0 38.3 19.9 21.0 16.7 31.2 UXT "ART-27, STAP1" ENSG00000126756 "Ubiquitously expressed prefoldin like chaperone" Q9UBK9 X 47651796-47659180 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Activator, Chaperone, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050499, HPA058400" Approved Supported "Nucleoplasm,Centriolar satellite" Yes No "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 24: NB-4 - Immune response" "Cluster 32: Non-specific - Translation" Nucleoplasm "Centriolar satellite" "HPA050499: AB_2681146, HPA058400: AB_2683706" "unprognostic (1.12e-1)" "unprognostic (3.85e-3)" "unprognostic (9.08e-2)" "unprognostic (2.09e-2)" "unprognostic (2.10e-1)" "unprognostic (2.23e-1)" "unprognostic (4.49e-2)" "unprognostic (1.24e-1)" "unprognostic (1.97e-1)" "unprognostic (2.31e-3)" "unprognostic (1.12e-2)" "unprognostic (1.17e-1)" "unprognostic (2.56e-2)" "unprognostic (1.44e-1)" "unprognostic (8.11e-2)" "unprognostic (8.64e-2)" "unprognostic (4.09e-3)" 124.7 148.6 82.1 78.8 84.9 212.0 127.1 85.6 111.7 121.8 86.5 112.3 77.2 93.6 123.6 116.6 103.3 66.7 144.6 80.1 85.1 134.2 135.1 97.8 148.7 87.1 82.5 184.6 182.3 90.5 107.0 65.3 88.4 119.7 99.7 42.8 121.6 65.9 130.7 143.6 113.8 68.2 87.7 139.5 131.7 46.3 83.7 166.9 96.3 95.2 143.0 109.6 111.9 91.1 192.0 208.6 87.4 116.0 194.3 233.4 152.3 119.2 178.5 203.6 191.7 182.1 178.1 217.3 86.4 173.5 188.0 151.8 123.5 163.8 145.3 143.7 240.8 111.6 220.8 182.4 224.2 246.6 208.1 162.9 207.5 168.6 183.8 142.2 165.9 185.6 122.2 205.1 174.8 211.5 170.7 342.1 125.4 174.7 231.2 149.5 177.2 300.9 168.1 141.4 82.1 107.1 133.1 146.7 197.8 157.7 170.4 227.2 122.4 140.7 153.2 196.2 136.7 161.7 154.5 200.7 179.8 270.1 145.1 110.1 159.7 123.4 169.5 166.1 229.8 262.7 242.6 184.2 213.3 245.2 303.2 255.4 100.7 172.1 156.9 270.3 248.2 247.9 82.1 84.9 85.6 111.7 80.1 85.1 87.1 82.5 88.4 87.7 83.7 91.1 108.3 73.7 79.5 5.5 276.8 214.9 274.3 247.9 212.3 27.3 242.1 239.6 100.7 165.8 141.4 97.5 16.7 189.4 207.2 212.1 315.0 161.2 73.5 122.3 125.2 129.6 187.2 170.0 4.0 318.9 212.6 127.6 78.0 114.0 154.1 161.4 193.5 242.4 246.5 10.1 4.3 331.9 126.1 248.0 277.4 185.2 210.3 179.8 197.5 1.9 316.0 108.2 212.1 3.5 7.7 189.3 338.0 196.0 198.3 256.4 297.8 466.1 138.0 28.6 144.7 224.3 145.2 78.7 85.6 183.3 203.7 213.7 240.5 185.5 328.5 286.0 VAX1 ENSG00000148704 "Ventral anterior homeobox 1" Q5SQQ9 10 117128521-117138301 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 15 "brain: 8.4" "Cell type enriched" "Detected in some" 4 "Inhibitory neurons: 7.4" "Not detected" "Not detected" "Region enhanced" "Detected in many" "hypothalamus: 8.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "A-431: 3.1;WM-115: 2.3" "Group enriched" "Detected in some" 6 "basal ganglia: 5.6;hypothalamus: 3.2;olfactory bulb: 1.5" "Low region specificity" "Detected in some" HPA028946 Uncertain Approved "Nucleoplasm,Nucleoli rim" Yes NA "Cluster 65: Brain - Ion transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoli rim" Nucleoplasm "HPA028946: AB_10602679" "unprognostic (1.08e-2)" "unprognostic (1.92e-2)" "unprognostic (1.46e-1)" "unprognostic (2.96e-2)" "unprognostic (5.77e-3)" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "unprognostic (5.72e-2)" "unprognostic (2.09e-1)" "unprognostic (2.99e-1)" 0.0 0.0 1.6 0.0 4.4 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 8.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.3 0.0 0.0 0.0 0.0 0.0 0.0 2.8 3.1 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 4.4 0.0 2.8 0.2 8.4 0.1 0.2 0.0 0.0 2.3 2.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 VLDLR "CARMQ1, CHRMQ1, VLDLRCH" ENSG00000147852 "Very low density lipoprotein receptor" P98155 9 2621182-2660056 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol metabolism, Endocytosis, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Receptor "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 77.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 78.1;Cone photoreceptor cells: 104.3;Oligodendrocytes: 39.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "eosinophil: 6.3" "Lineage enriched" "Detected in single" 10 "granulocytes: 6.3" "Cell line enhanced" "Detected in many" "BEWO: 22.3;JURKAT: 20.5;THP-1: 33.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032462, HPA051312" Uncertain Uncertain "Vesicles,Cytokinetic bridge,Centriolar satellite" Yes NA 330000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "Cytokinetic bridge, Centriolar satellite" "CAB032462: AB_2216805, HPA051312: " "unprognostic (5.31e-2)" "unprognostic (2.65e-1)" "unprognostic (6.92e-2)" "prognostic favorable (5.95e-4)" "unprognostic (1.15e-1)" "unprognostic (2.67e-2)" "unprognostic (2.48e-3)" "unprognostic (1.76e-1)" "unprognostic (1.52e-1)" "unprognostic (3.00e-2)" "unprognostic (3.79e-2)" "unprognostic (2.33e-1)" "unprognostic (6.75e-2)" "unprognostic (1.48e-2)" "unprognostic (1.93e-1)" "unprognostic (1.80e-2)" "unprognostic (4.34e-2)" 15.7 16.3 2.7 2.2 6.4 0.8 8.5 5.3 4.2 10.3 6.4 6.6 0.5 9.6 3.2 19.2 13.8 2.9 43.7 3.2 5.3 10.6 3.1 10.7 0.7 7.7 5.6 77.5 27.4 19.5 6.5 5.9 5.9 6.6 2.0 12.3 11.6 2.0 26.2 5.3 1.9 6.8 4.0 5.5 9.0 6.0 4.9 0.8 11.6 11.7 1.7 12.5 10.4 9.8 0.1 0.8 14.3 0.4 1.5 0.5 22.3 7.0 2.2 1.7 4.3 3.6 0.3 0.0 6.4 2.8 0.6 0.3 3.4 5.6 4.5 9.7 2.4 0.1 1.6 1.8 1.9 9.2 1.7 1.5 3.3 0.7 0.1 7.6 0.7 20.5 0.0 17.4 1.1 0.9 1.1 1.1 9.9 1.5 0.9 0.1 0.4 0.0 6.4 0.4 2.5 2.4 0.6 0.6 10.4 7.5 0.3 33.3 0.3 2.8 4.5 0.1 3.3 14.1 6.1 2.6 14.7 8.2 0.6 0.0 0.0 6.3 0.2 0.0 0.6 0.0 0.0 0.2 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.5 0.0 0.0 2.7 6.4 5.3 4.2 3.2 5.3 7.7 5.6 5.9 4.0 4.9 9.8 4.2 16.0 8.8 1.0 0.1 2.7 1.2 18.7 4.6 23.8 4.3 3.9 78.1 1.5 9.7 5.5 104.3 13.2 1.6 9.8 1.9 11.3 5.7 8.6 6.1 3.6 10.9 0.0 8.3 10.3 29.0 17.2 3.1 19.3 0.0 5.7 2.2 2.8 2.3 11.8 10.9 1.4 24.4 1.0 1.1 2.8 7.8 0.6 10.6 2.8 1.0 3.9 0.0 8.0 39.1 8.6 4.3 10.9 0.5 5.1 0.0 8.0 11.9 32.5 0.0 2.7 9.4 8.2 6.4 5.0 2.0 3.4 1.7 15.9 1.3 6.0 VPS4A "FLJ22197, SKD1, SKD1A, SKD2, VPS4, VPS4-1" ENSG00000132612 "Vacuolar protein sorting 4 homolog A" Q9UN37 16 69311350-69326939 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transport" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB018751, CAB034411, HPA060092" Approved Supported Midbody Yes NA "Cluster 26: Non-specific - Mitochondria" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Midbody "CAB018751: AB_2215497, CAB034411: AB_2304400, HPA060092: AB_2684203" "unprognostic (2.60e-2)" "unprognostic (2.32e-2)" "unprognostic (1.26e-1)" "unprognostic (9.26e-2)" "unprognostic (4.03e-1)" "unprognostic (1.20e-1)" "unprognostic (2.55e-2)" "unprognostic (2.70e-2)" "unprognostic (4.63e-2)" "unprognostic (8.61e-2)" "unprognostic (3.91e-3)" "unprognostic (2.19e-1)" "prognostic favorable (1.76e-4)" "unprognostic (5.44e-2)" "unprognostic (1.46e-1)" "unprognostic (2.61e-1)" "unprognostic (6.79e-2)" 13.2 15.3 15.7 8.9 16.9 8.8 12.8 16.1 17.1 10.4 11.0 13.5 13.5 11.7 8.1 16.0 10.3 9.4 20.6 15.5 14.9 18.0 11.6 9.9 11.8 16.4 16.8 12.2 27.8 20.6 7.6 10.0 16.7 10.4 7.6 10.2 19.9 8.4 54.0 15.3 12.8 8.4 15.4 9.2 17.6 6.8 16.7 6.2 16.7 33.6 7.3 11.4 11.3 18.2 21.1 34.9 23.2 30.7 21.2 18.8 20.5 27.9 25.2 36.4 24.3 33.4 19.0 35.0 27.3 28.0 17.5 30.3 23.9 28.2 21.8 14.8 30.8 22.0 20.7 26.3 32.6 27.5 19.6 21.7 36.3 31.6 28.7 21.4 27.4 27.3 37.0 10.3 27.2 46.8 36.4 20.5 26.7 20.6 24.5 47.8 19.0 41.3 18.5 16.8 39.1 24.7 59.3 18.1 21.4 15.4 31.4 20.6 32.8 33.2 20.8 30.4 22.1 36.9 31.3 62.6 30.4 18.2 37.1 8.8 9.9 13.3 11.2 8.7 10.0 8.5 9.3 13.9 9.4 7.4 10.5 9.9 7.5 8.0 11.5 5.5 11.8 13.8 15.7 16.9 16.1 17.1 15.5 14.9 16.4 16.8 16.7 15.4 16.7 18.2 39.8 25.6 19.0 14.7 33.8 30.7 37.3 22.2 22.8 51.4 30.2 28.2 31.0 22.8 16.7 23.9 22.9 59.8 48.4 48.9 74.3 51.7 11.2 14.9 27.0 34.9 31.3 43.6 14.5 82.5 66.5 32.9 29.0 25.6 29.2 36.3 31.8 21.6 45.1 74.0 14.9 34.2 20.3 33.7 24.6 11.9 29.5 30.2 44.4 5.6 40.9 66.0 38.1 4.5 16.8 67.4 42.2 30.5 31.9 67.6 76.4 57.7 6.4 41.8 52.6 36.0 38.9 28.7 38.3 27.1 31.3 70.1 35.6 26.0 41.4 41.2 VRK1 ENSG00000100749 "VRK serine/threonine kinase 1" Q99986 14 96797304-96954846 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 50.4;testis: 37.1" "Cell type enhanced" "Detected in all" "Spermatocytes: 198.9;Spermatogonia: 110.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000660, HPA017929" Enhanced Supported Nucleoplasm,Cytosol Yes No "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA000660: AB_1080579, HPA017929: AB_1858770" "unprognostic (1.03e-1)" "unprognostic (1.17e-2)" "unprognostic (1.84e-2)" "unprognostic (2.24e-3)" "unprognostic (5.42e-2)" "unprognostic (1.19e-2)" "prognostic unfavorable (4.15e-4)" "unprognostic (4.20e-2)" "unprognostic (2.11e-2)" "unprognostic (5.47e-2)" "unprognostic (5.14e-2)" "unprognostic (1.60e-1)" "unprognostic (2.53e-2)" "unprognostic (6.70e-2)" "unprognostic (4.56e-2)" "unprognostic (3.36e-2)" "unprognostic (1.58e-1)" 5.9 5.2 5.9 12.8 7.1 50.4 11.5 6.0 7.9 5.2 4.3 10.8 6.5 6.5 6.9 8.9 9.2 4.4 5.2 5.9 5.1 4.9 5.5 4.9 27.1 5.3 5.5 6.0 3.2 5.4 3.1 7.6 5.4 5.0 12.3 4.4 4.3 5.0 4.7 7.4 7.2 6.7 4.8 11.3 6.5 37.1 5.9 35.5 5.9 4.6 27.9 7.7 5.4 7.0 52.4 27.0 78.5 30.2 9.2 14.9 44.8 42.8 34.4 67.1 65.4 36.0 54.7 139.2 22.4 24.3 39.2 56.5 75.5 54.4 90.5 73.4 36.4 90.5 18.7 39.3 10.2 168.5 49.2 8.5 9.7 50.4 32.6 12.8 47.0 104.8 76.6 79.0 56.9 65.5 137.1 76.5 47.8 39.9 59.3 124.5 134.2 48.6 32.3 59.3 53.2 28.0 34.2 36.4 30.8 36.0 39.3 66.6 24.4 27.9 22.8 47.7 37.3 37.7 53.5 124.8 44.7 74.6 34.8 42.7 12.3 26.2 21.5 15.5 29.0 31.3 24.9 26.4 15.7 32.7 27.1 27.3 6.5 45.6 15.2 21.4 34.9 19.4 5.9 7.1 6.0 7.9 5.9 5.1 5.3 5.5 5.4 4.8 5.9 7.0 15.3 3.2 4.6 6.8 30.6 16.8 13.8 23.3 6.2 12.4 9.3 11.3 11.8 12.8 16.7 14.7 8.4 34.8 24.8 6.3 11.7 13.5 21.3 21.1 8.3 12.4 3.0 76.2 42.0 19.4 48.3 11.4 14.8 10.8 28.5 20.0 7.1 3.3 19.2 10.1 36.2 10.4 20.3 11.8 14.9 11.5 5.6 12.0 12.4 19.7 14.2 6.2 27.8 12.1 19.8 10.3 2.2 9.8 25.4 6.1 3.0 11.2 37.6 9.6 19.7 14.3 15.1 198.9 110.9 14.1 13.9 15.1 26.8 9.2 18.1 10.4 WDPCP "BBS15, C2orf86, CPLANE5, fritz, hFrtz" ENSG00000143951 "WD repeat containing planar cell polarity effector" O95876 2 63119559-63827843 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Mental retardation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 18.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 169.9;Alveolar cells type 2: 128.0;Astrocytes: 124.7;Excitatory neurons: 261.4;Inhibitory neurons: 240.9;Oligodendrocyte precursor cells: 136.2;Oligodendrocytes: 296.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044144 Uncertain Approved "Cell Junctions" Yes No "Cluster 41: Basophils - Cellular respiration" "Cluster 6: Brain - Smell perception" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Cell Junctions" "HPA044144: AB_10969458" "unprognostic (3.36e-1)" "unprognostic (3.22e-2)" "unprognostic (1.95e-1)" "unprognostic (7.07e-2)" "unprognostic (2.95e-1)" "unprognostic (6.88e-2)" "unprognostic (1.71e-1)" "unprognostic (1.59e-3)" "unprognostic (7.22e-2)" "unprognostic (6.48e-2)" "unprognostic (1.93e-1)" "unprognostic (4.87e-2)" "unprognostic (2.34e-3)" "unprognostic (6.02e-2)" "unprognostic (1.97e-1)" "unprognostic (2.25e-3)" "unprognostic (2.00e-1)" 4.7 3.5 11.3 2.5 11.7 8.2 3.2 17.7 15.7 2.5 6.5 1.6 1.8 3.9 4.0 2.0 4.2 2.8 4.9 10.4 6.9 3.6 2.4 2.5 3.3 6.4 5.4 4.6 1.5 2.9 1.9 2.6 8.4 2.6 1.8 12.2 2.2 2.1 5.3 3.4 1.7 3.0 3.2 3.3 3.3 5.1 6.3 3.6 3.5 2.9 2.7 1.8 1.1 18.6 5.2 4.6 3.3 4.0 3.7 4.6 3.0 4.3 2.2 2.8 2.3 3.3 2.6 5.8 3.5 2.9 3.3 3.4 2.3 2.8 3.3 5.7 3.8 6.1 3.5 2.8 2.5 5.0 4.1 2.3 1.9 2.9 1.9 3.7 2.9 6.7 2.3 5.7 2.9 5.3 5.8 5.1 3.9 2.7 1.7 6.2 4.3 5.0 1.9 2.5 5.2 5.2 3.7 4.4 5.3 4.7 3.8 3.9 4.7 4.6 7.2 4.0 3.6 5.3 3.6 10.3 5.2 5.3 5.3 6.6 2.8 1.5 1.9 1.5 3.7 1.8 1.7 2.6 2.3 3.1 2.3 3.6 1.9 3.8 1.3 2.7 1.5 1.1 11.3 11.7 17.7 15.7 10.4 6.9 6.4 5.4 8.4 3.2 6.3 18.6 6.0 169.9 128.0 124.7 8.0 4.1 3.2 4.3 2.8 16.1 4.4 3.2 10.1 7.2 59.6 1.8 22.9 2.5 5.5 0.8 1.9 2.6 46.7 17.9 6.2 14.4 0.0 7.8 261.4 2.2 2.6 13.5 6.6 3.7 65.0 7.4 5.0 1.8 4.0 11.8 240.9 1.3 4.1 3.0 4.4 17.5 4.4 8.4 5.4 103.0 3.8 7.5 6.2 136.2 296.3 1.8 1.6 3.8 5.1 1.5 0.5 4.5 98.8 27.4 0.0 8.6 5.7 16.1 9.5 2.3 3.4 1.9 9.4 4.0 1.1 1.7 WIZ ZNF803 ENSG00000011451 "WIZ zinc finger" O95785 19 15419978-15449956 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022923, HPA023774" Supported Enhanced Nucleoplasm,Midbody Yes No "Cluster 14: Monocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm Midbody "HPA022923: AB_1858845, HPA023774: AB_2671308" "unprognostic (3.50e-2)" "unprognostic (3.91e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (5.12e-5)" "unprognostic (1.05e-1)" "unprognostic (4.96e-3)" "unprognostic (9.73e-3)" "unprognostic (3.00e-1)" "unprognostic (2.24e-2)" "unprognostic (4.69e-2)" "unprognostic (7.46e-2)" "unprognostic (5.47e-2)" "unprognostic (2.65e-1)" "unprognostic (4.27e-2)" "unprognostic (1.11e-1)" "unprognostic (2.31e-2)" "unprognostic (2.11e-1)" 13.9 13.7 22.2 10.2 18.0 7.5 13.2 11.1 28.2 13.5 8.3 15.8 9.6 18.7 3.6 12.2 13.4 6.6 18.7 21.4 12.2 13.3 12.3 9.9 6.6 14.0 15.4 14.0 19.7 9.3 7.9 6.7 13.7 12.0 3.5 3.6 10.4 10.3 14.4 13.7 10.2 8.3 12.2 9.5 15.8 21.3 17.7 6.6 9.1 7.3 4.0 16.0 11.6 15.7 23.0 13.1 22.6 28.0 32.2 13.4 17.0 23.2 10.8 19.8 13.4 14.1 43.0 18.8 36.7 22.9 12.1 20.3 12.5 17.3 5.0 13.8 21.3 14.6 13.5 11.3 21.2 15.2 19.9 23.8 22.9 14.7 16.4 12.3 18.3 14.4 22.5 16.8 13.8 48.4 30.2 15.9 28.7 23.8 38.2 27.7 10.4 19.9 13.2 18.5 31.0 36.4 20.2 19.5 15.7 8.3 21.4 16.0 29.2 45.4 16.7 36.0 32.0 22.8 15.6 21.2 18.0 19.1 31.5 0.0 0.3 0.0 0.2 0.2 0.2 0.1 0.1 0.2 0.2 0.3 0.2 0.2 0.1 0.5 1.0 0.3 0.2 0.1 22.2 18.0 11.1 28.2 21.4 12.2 14.0 15.4 13.7 12.2 17.7 15.7 11.3 12.8 6.9 6.5 4.1 15.8 7.2 7.8 5.7 9.4 16.2 17.8 10.9 8.6 5.6 12.9 0.0 7.1 8.4 8.4 3.9 14.9 9.0 6.3 15.3 14.9 6.7 3.0 3.2 20.0 9.9 10.3 9.2 12.1 1.3 17.3 14.3 14.7 7.8 6.7 3.2 9.0 4.1 11.3 7.2 10.0 15.8 8.7 7.2 3.7 6.7 8.5 2.1 2.0 2.8 19.1 3.9 19.2 3.1 14.1 6.2 5.3 2.5 7.4 13.1 9.5 12.7 34.8 21.9 9.3 20.3 7.4 5.4 16.8 10.0 12.8 XAF1 "BIRC4BP, HSXIAPAF1, XIAPAF1" ENSG00000132530 "XIAP associated factor 1" Q6GPH4 17 6755447-6775647 "Predicted intracellular proteins" Apoptosis "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 174.2;Endothelial cells: 90.4;Microglial cells: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 81.8;BJ hTERT+ SV40 Large T+ RasG12V: 83.8;HHSteC: 35.3" "Low region specificity" "Detected in all" HPA057302 Approved Supported Nucleoplasm,Mitochondria Yes NA "Cluster 51: Monocytes - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Mitochondria" "HPA057302: AB_2683405" "unprognostic (6.28e-2)" "unprognostic (1.71e-1)" "unprognostic (8.62e-3)" "unprognostic (1.28e-2)" "unprognostic (3.81e-1)" "unprognostic (1.11e-2)" "unprognostic (5.09e-3)" "unprognostic (4.89e-2)" "unprognostic (1.39e-1)" "unprognostic (8.08e-3)" "unprognostic (3.34e-3)" "unprognostic (1.79e-1)" "prognostic unfavorable (2.73e-7)" "unprognostic (2.33e-1)" "unprognostic (1.74e-2)" "unprognostic (2.31e-1)" "unprognostic (6.15e-3)" 31.9 12.8 28.3 29.7 29.8 33.4 24.2 27.7 39.6 42.3 23.8 17.5 26.8 26.5 13.0 17.0 22.5 34.0 30.9 27.5 29.2 23.5 63.6 35.8 29.7 37.5 28.4 52.9 2.9 2.9 14.3 25.9 30.8 24.9 16.8 4.8 47.6 11.2 14.1 18.4 25.4 24.3 31.9 63.4 23.6 9.2 31.5 23.8 18.2 13.5 15.5 17.3 22.1 27.5 5.2 0.3 0.7 1.4 6.7 15.1 0.7 7.1 26.3 81.8 83.8 0.7 7.5 1.3 2.0 10.2 28.9 3.1 0.0 1.3 9.3 11.4 0.3 1.9 0.9 1.0 35.3 1.2 8.0 6.9 0.0 11.3 0.3 0.4 6.9 25.5 0.7 26.1 2.6 0.4 6.3 22.1 0.6 0.2 2.2 11.3 0.4 0.5 0.2 4.9 0.5 0.6 3.6 0.5 14.3 0.6 0.8 30.4 0.7 1.1 0.8 2.3 0.5 3.9 1.4 0.5 2.6 18.4 2.2 17.4 9.6 4.3 7.8 12.7 5.7 3.6 6.0 5.6 8.0 4.6 3.8 4.0 10.6 8.0 12.5 0.8 9.9 5.6 28.3 29.8 27.7 39.6 27.5 29.2 37.5 28.4 30.8 31.9 31.5 27.5 174.2 60.9 29.9 14.0 25.7 5.2 5.7 5.5 13.1 0.5 4.1 10.3 2.7 8.6 30.0 0.0 0.0 0.4 37.1 12.4 0.0 1.3 4.0 18.9 68.4 90.4 1.8 10.7 0.3 1.9 5.1 29.8 27.5 10.4 48.7 44.4 33.5 20.1 15.9 0.0 0.3 9.2 0.0 21.3 11.2 2.6 36.4 54.4 5.4 103.0 44.5 1.1 70.0 1.5 0.6 10.1 2.7 27.4 11.4 2.5 11.4 0.3 24.3 0.4 19.7 27.3 19.0 0.2 0.8 11.8 2.7 0.4 35.1 47.3 9.2 5.6 XPA "XP1, XPAC" ENSG00000136936 "XPA, DNA damage recognition and repair factor" P23025 9 97674909-97697340 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000155, HPA056856" Supported Approved "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Cytokinetic bridge" "CAB000155: , HPA056856: AB_2683258" "unprognostic (8.76e-2)" "unprognostic (1.05e-3)" "unprognostic (1.60e-1)" "unprognostic (2.30e-2)" "unprognostic (4.17e-1)" "unprognostic (1.84e-1)" "unprognostic (5.26e-2)" "unprognostic (2.38e-1)" "unprognostic (3.90e-2)" "unprognostic (1.28e-1)" "unprognostic (1.97e-3)" "unprognostic (9.55e-3)" "prognostic favorable (4.28e-5)" "unprognostic (2.19e-2)" "unprognostic (1.56e-1)" "unprognostic (3.03e-2)" "unprognostic (1.17e-1)" 15.1 13.4 9.9 9.5 10.3 9.1 13.4 12.0 15.4 13.9 10.8 23.0 15.8 14.0 11.0 14.9 13.1 9.7 9.9 9.7 10.8 18.4 18.8 11.3 14.0 10.2 10.0 13.0 11.8 18.7 9.9 9.7 9.8 14.8 9.9 10.6 12.5 12.7 19.5 12.5 13.1 12.0 9.7 12.5 21.6 5.2 10.7 11.0 23.6 8.6 17.2 15.4 13.5 10.6 35.5 8.2 11.9 14.8 14.3 13.7 8.2 9.4 14.9 16.9 11.4 21.4 28.9 19.9 8.9 10.5 11.3 17.4 9.6 11.4 14.1 13.7 19.2 15.7 17.7 12.0 15.5 18.7 18.2 12.0 12.0 7.9 8.0 11.4 19.1 16.1 22.0 15.2 9.4 11.0 24.4 22.5 8.2 33.5 13.5 24.6 25.4 17.0 27.0 13.7 16.7 16.7 13.4 10.3 12.7 9.0 14.9 11.1 12.0 5.9 14.8 23.4 20.6 26.5 22.7 12.3 14.6 13.2 11.8 12.8 21.6 22.6 25.5 23.0 30.1 34.4 27.9 25.0 23.0 40.5 33.5 29.0 2.6 35.2 29.7 39.8 33.1 19.6 9.9 10.3 12.0 15.4 9.7 10.8 10.2 10.0 9.8 9.7 10.7 10.6 32.4 25.6 37.8 49.0 36.1 17.3 23.3 39.3 31.9 101.4 24.8 31.9 36.2 45.8 39.7 22.0 81.3 32.1 47.2 10.6 121.3 36.3 1.7 22.5 29.1 30.4 22.3 11.1 49.3 38.3 9.7 31.3 22.4 17.2 30.9 28.0 28.2 48.7 36.0 84.1 63.5 24.6 30.5 27.7 20.7 4.0 44.1 24.5 14.2 40.3 49.6 87.0 64.9 74.9 96.0 29.3 19.2 47.4 26.2 18.9 32.1 55.5 28.6 97.5 32.9 38.3 39.4 18.2 17.9 28.5 18.8 14.0 34.9 36.4 24.2 23.5 Z82206.1 ENSG00000225528 "Novel protein similar to translation machinery associated 7 homolog (S. cerevisiae) TMA7" 22 39960397-39964718 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 1.3;lymphoid tissue: 4.3" "Cell type enhanced" "Detected in some" "Distal tubular cells: 7.9;granulocytes: 3.8;Proximal tubular cells: 3.2;T-cells: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 4 "K-562: 12.5" HPA047397 Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies" Yes NA "Cluster 2: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoli, Nucleoli rim" "Nucleoplasm, Nuclear bodies" "HPA047397: AB_2680029" "unprognostic (8.48e-4)" "unprognostic (2.95e-6)" "unprognostic (3.67e-1)" "unprognostic (5.90e-2)" "unprognostic (4.27e-1)" "unprognostic (6.95e-3)" "unprognostic (3.74e-1)" "unprognostic (5.41e-4)" "unprognostic (2.33e-1)" "unprognostic (2.13e-2)" "unprognostic (1.18e-3)" "unprognostic (8.77e-2)" "unprognostic (6.53e-5)" "unprognostic (1.89e-1)" "unprognostic (1.70e-1)" "unprognostic (1.11e-1)" "unprognostic (6.58e-3)" 0.1 0.0 0.0 0.2 0.0 1.3 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.9 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.0 1.1 0.1 0.1 0.0 4.3 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.4 12.5 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 1.1 2.7 2.9 1.3 2.5 2.3 3.5 3.2 1.6 2.0 3.6 4.4 2.4 1.3 1.2 1.7 2.6 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 7.9 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 ZBTB24 "BIF1, KIAA0441, PATZ2, ZNF450" ENSG00000112365 "Zinc finger and BTB domain containing 24" O43167 6 109462594-109483219 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 65.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017872, HPA049003" Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Centrosome" Yes No "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Cytokinetic bridge, Centrosome" "HPA017872: AB_2669673, HPA049003: AB_2680596" "unprognostic (8.15e-2)" "unprognostic (1.56e-1)" "unprognostic (1.03e-1)" "unprognostic (1.41e-1)" "unprognostic (4.80e-2)" "unprognostic (1.98e-2)" "prognostic unfavorable (3.15e-4)" "unprognostic (4.53e-2)" "unprognostic (5.09e-2)" "unprognostic (3.31e-2)" "unprognostic (1.22e-3)" "unprognostic (1.37e-1)" "unprognostic (1.75e-3)" "unprognostic (1.26e-1)" "unprognostic (2.69e-1)" "unprognostic (2.60e-1)" "unprognostic (6.77e-2)" 3.1 2.2 1.5 5.4 2.4 8.9 4.6 2.4 2.4 4.0 1.0 3.5 3.6 3.1 3.2 3.0 2.9 2.5 2.2 1.6 1.9 3.9 2.6 3.9 8.7 1.5 1.2 3.4 3.5 7.4 1.8 3.2 1.6 3.5 3.8 10.1 4.4 3.3 3.2 4.7 3.7 2.8 1.3 5.5 4.1 4.3 1.6 6.9 4.9 2.9 7.3 3.5 2.7 2.9 4.7 4.8 4.3 10.8 6.8 6.9 7.0 5.3 7.3 6.5 7.4 6.7 3.6 20.0 6.7 6.7 7.8 6.0 10.9 8.3 9.8 12.4 10.7 16.2 6.5 5.1 5.0 13.3 8.0 7.0 6.7 6.6 11.4 4.6 5.5 9.3 13.8 11.0 6.8 8.0 19.2 9.0 10.7 4.7 5.3 11.9 6.1 8.3 8.0 8.0 7.3 6.4 6.8 7.1 16.9 5.9 5.0 14.5 5.4 5.3 5.3 4.4 11.5 5.3 4.4 20.2 7.0 10.4 9.0 0.1 0.6 0.9 0.7 0.6 0.4 3.4 1.5 0.9 0.7 2.8 1.9 1.1 0.4 1.3 0.8 1.1 2.9 0.5 1.5 2.4 2.4 2.4 1.6 1.9 1.5 1.2 1.6 1.3 1.6 2.9 8.4 12.8 9.1 2.6 32.8 10.1 11.2 5.3 7.4 21.7 8.6 7.4 3.8 7.2 5.2 3.7 31.3 8.5 16.8 4.5 3.9 6.6 1.4 7.3 14.3 6.6 9.6 12.0 3.3 9.1 9.9 8.6 12.8 10.7 9.5 14.1 3.6 7.3 7.7 10.1 2.8 11.0 6.1 12.5 12.1 1.8 7.2 10.3 8.8 5.6 20.5 10.0 14.4 1.0 5.4 6.4 5.1 6.4 16.8 8.2 7.4 6.4 6.0 65.2 0.0 13.2 7.4 6.2 27.8 9.3 9.7 7.8 17.8 15.0 8.5 7.3 ZFHX2 "KIAA1056, KIAA1762, ZFH-5, ZNF409" ENSG00000136367 "Zinc finger homeobox 2" Q9C0A1 14 23520857-23556192 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.9;testis: 7.3" "Cell type enhanced" "Detected in many" "Astrocytes: 22.5;Early spermatids: 38.9;Excitatory neurons: 31.0;Inhibitory neurons: 20.0;Late spermatids: 19.1;Oligodendrocyte precursor cells: 27.2;Oligodendrocytes: 20.8;Spermatocytes: 16.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 11.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 4.8;SuSa: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000720, HPA005146" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoli fibrillar center" Nucleoplasm "HPA000720: AB_10603462, HPA005146: AB_1859250" "unprognostic (7.54e-3)" "unprognostic (2.01e-1)" "unprognostic (1.53e-1)" "unprognostic (2.53e-1)" "unprognostic (2.61e-1)" "unprognostic (6.12e-3)" "unprognostic (1.40e-1)" "unprognostic (5.40e-2)" "unprognostic (3.94e-2)" "unprognostic (3.71e-2)" "unprognostic (5.08e-4)" "unprognostic (2.39e-1)" "unprognostic (5.33e-3)" "unprognostic (3.75e-1)" "unprognostic (7.35e-2)" "unprognostic (1.76e-1)" "unprognostic (1.90e-2)" 0.5 0.7 1.8 0.5 6.3 0.1 0.4 11.9 5.3 0.4 0.0 0.7 0.1 0.7 0.4 0.2 2.2 0.4 0.3 3.2 0.0 1.3 0.2 0.5 0.3 1.5 0.1 0.5 0.4 1.7 3.4 0.2 0.2 0.6 0.2 3.1 0.4 1.2 0.7 0.5 0.3 0.6 0.0 0.2 0.4 7.3 0.9 0.2 0.7 0.5 0.2 0.3 0.2 2.3 0.1 3.1 2.4 4.8 1.6 0.2 0.1 0.7 0.2 0.3 1.2 0.3 0.2 0.2 0.3 0.0 0.3 0.1 1.2 0.1 0.5 2.2 0.8 2.5 0.0 0.6 0.2 0.4 1.7 0.3 0.1 0.5 0.1 1.3 0.3 2.1 0.4 0.4 0.1 0.8 0.3 0.3 2.9 0.3 0.7 1.4 0.0 0.0 1.3 1.2 2.7 1.7 0.4 0.6 0.1 3.6 1.0 0.6 0.1 0.0 1.2 0.7 0.3 0.3 1.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.8 6.3 11.9 5.3 3.2 0.0 1.5 0.1 0.2 0.0 0.9 2.3 0.5 0.0 1.1 22.5 0.7 0.1 0.6 1.1 0.0 9.0 2.2 2.3 2.5 0.0 2.4 1.8 0.0 0.3 0.1 0.6 1.9 2.8 38.9 12.2 0.6 1.1 6.7 0.0 31.0 2.4 0.0 1.4 2.0 2.5 0.0 3.2 0.7 0.2 1.0 8.4 20.0 0.7 2.0 1.0 1.9 19.1 0.6 0.8 0.0 4.7 1.0 2.7 0.0 27.2 20.8 1.2 1.2 0.4 0.1 1.4 0.4 1.4 9.8 3.8 0.0 2.5 1.3 16.5 1.2 0.7 0.0 0.3 0.4 0.2 0.6 0.3 ZFP37 ZNF906 ENSG00000136866 "ZFP37 zinc finger protein" Q9Y6Q3 9 113038377-113056759 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 15.5;Oligodendrocyte precursor cells: 23.6;Oligodendrocytes: 29.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 2.4" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049112 Uncertain Approved Nucleoplasm,Vesicles Yes No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 21: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Vesicles" "HPA049112: AB_2680637" "unprognostic (3.18e-1)" "unprognostic (9.57e-2)" "unprognostic (5.62e-2)" "unprognostic (3.54e-3)" "prognostic favorable (1.96e-4)" "unprognostic (7.84e-2)" "unprognostic (8.09e-2)" "unprognostic (2.70e-3)" "unprognostic (1.47e-1)" "unprognostic (2.53e-2)" "unprognostic (2.51e-2)" "unprognostic (1.38e-3)" "unprognostic (4.22e-2)" "unprognostic (9.46e-2)" "unprognostic (3.67e-1)" "unprognostic (4.86e-1)" "unprognostic (2.07e-1)" 1.6 1.7 2.2 1.3 2.9 0.2 2.8 4.4 2.5 3.0 0.5 1.6 0.8 4.5 1.8 1.2 2.5 1.3 1.5 1.9 2.7 2.3 0.6 1.3 1.2 2.3 2.2 7.1 1.3 2.9 3.8 1.3 2.5 2.5 1.0 6.3 0.9 1.8 1.4 1.2 1.1 2.5 2.5 2.0 1.2 2.2 3.3 1.2 2.9 1.9 1.3 1.8 1.6 4.0 0.6 1.7 7.2 6.0 3.9 7.5 3.7 2.3 3.4 2.5 2.1 0.0 1.7 4.2 1.8 2.4 3.3 1.5 0.0 0.9 3.9 5.2 0.8 0.2 3.5 1.9 2.1 0.0 0.8 2.1 0.7 3.0 5.8 6.1 1.4 0.0 0.4 3.6 5.2 0.0 0.0 0.0 7.4 4.4 0.0 0.0 10.0 0.6 1.9 0.0 6.1 5.8 7.1 1.5 1.4 3.5 6.0 0.0 0.6 5.8 2.5 6.9 3.5 1.4 2.9 0.0 4.5 0.1 3.6 0.1 0.0 0.0 0.9 0.2 0.7 0.9 0.8 0.9 0.3 0.4 0.6 0.9 0.1 0.7 0.0 0.0 2.4 0.3 2.2 2.9 4.4 2.5 1.9 2.7 2.3 2.2 2.5 2.5 3.3 4.0 3.4 0.0 0.5 5.5 2.1 0.3 0.9 1.3 2.2 10.3 1.4 2.8 8.0 0.0 0.5 0.0 6.2 0.8 1.6 0.1 3.9 1.6 1.0 0.6 4.9 3.2 1.2 0.0 9.2 0.9 1.6 3.8 2.6 0.6 5.7 2.5 2.5 1.3 0.5 6.7 15.5 0.6 4.1 0.3 0.3 0.2 2.1 0.8 0.0 3.7 0.5 3.4 3.1 23.6 29.7 0.4 1.3 2.2 1.1 0.5 0.1 3.1 0.4 6.0 6.6 6.4 4.2 5.6 3.2 2.7 0.0 0.1 1.3 2.6 0.3 0.4 ZKSCAN1 "KOX18, PHZ-37, ZNF139, ZNF36, ZSCAN33" ENSG00000106261 "Zinc finger with KRAB and SCAN domains 1" P17029 7 100015572-100041689 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 272.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006672 Uncertain Approved "Nucleoplasm,Nuclear bodies,Mitochondria" Yes No "Cluster 18: Basophils - Vesicular transport" "Cluster 15: Liver - Metabolism" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Nuclear bodies" "Nucleoplasm, Mitochondria" "HPA006672: AB_1080707" "unprognostic (2.58e-1)" "unprognostic (1.59e-2)" "unprognostic (3.57e-2)" "unprognostic (4.62e-2)" "unprognostic (1.94e-1)" "unprognostic (2.24e-2)" "unprognostic (1.47e-2)" "unprognostic (4.76e-3)" "unprognostic (3.24e-2)" "unprognostic (1.86e-2)" "unprognostic (6.34e-3)" "unprognostic (8.59e-2)" "unprognostic (1.27e-3)" "unprognostic (7.75e-2)" "unprognostic (1.49e-1)" "unprognostic (1.70e-1)" "unprognostic (9.09e-3)" 12.0 18.4 20.2 11.6 29.1 8.7 22.7 17.2 22.1 16.4 7.4 21.5 18.2 15.5 17.1 18.8 21.7 13.9 10.1 14.4 23.8 13.3 52.8 10.9 11.7 21.3 23.2 19.0 26.1 16.5 10.9 11.0 23.4 23.0 23.5 15.8 25.3 10.8 10.4 32.6 16.9 13.7 13.9 13.5 32.6 11.1 24.1 14.2 11.9 8.8 11.9 12.2 17.4 37.5 17.0 12.3 31.8 34.6 32.0 38.7 12.0 18.6 22.5 10.9 11.0 7.4 15.7 19.1 23.0 20.9 19.1 13.7 18.4 16.1 20.6 18.4 11.3 15.5 15.8 19.3 18.0 29.9 17.7 26.1 25.1 14.7 49.0 29.5 24.4 22.2 36.2 16.3 21.7 22.4 28.4 17.6 12.8 31.6 15.2 16.7 16.2 17.3 18.2 26.4 36.8 44.0 28.9 37.4 32.4 17.8 19.1 19.6 36.8 23.7 23.0 27.9 18.9 18.7 35.3 19.5 16.2 20.8 31.7 16.0 4.0 4.1 5.0 3.1 4.9 3.8 3.9 4.9 5.8 4.8 5.3 3.9 4.2 8.8 9.0 3.9 3.5 3.8 20.2 29.1 17.2 22.1 14.4 23.8 21.3 23.2 23.4 13.9 24.1 37.5 45.3 25.6 55.4 57.5 37.0 15.0 45.7 43.4 71.7 93.9 77.6 38.7 42.8 140.2 61.4 46.0 150.1 41.1 40.1 84.8 15.6 55.9 46.5 89.2 90.9 52.2 220.9 24.6 70.1 43.8 15.3 47.9 103.5 68.0 35.4 120.5 44.6 140.8 19.8 89.2 77.7 99.2 77.3 32.7 18.6 18.4 51.3 31.2 40.9 62.8 45.8 61.2 34.0 102.1 272.5 46.6 81.3 53.4 27.1 93.1 70.4 32.4 153.6 70.1 19.7 87.4 43.9 32.8 16.7 62.9 21.5 65.9 32.3 74.0 114.4 62.0 ZNF202 "ZKSCAN10, ZSCAN42" ENSG00000166261 "Zinc finger protein 202" O95125 11 123723914-123741675 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 14.7;Spermatogonia: 14.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059229 Approved "Nucleoli rim,Nuclear bodies,Mitotic chromosome" Yes No "Cluster 32: T-cells - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoli rim, Mitotic chromosome" "Nuclear bodies" "HPA059229: " "unprognostic (3.12e-2)" "unprognostic (7.75e-2)" "unprognostic (2.20e-2)" "unprognostic (4.49e-2)" "unprognostic (2.10e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (2.52e-6)" "unprognostic (1.23e-1)" "unprognostic (1.74e-3)" "unprognostic (2.80e-1)" "unprognostic (9.48e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (9.93e-7)" "unprognostic (2.61e-2)" "unprognostic (2.11e-2)" "unprognostic (1.17e-1)" "unprognostic (1.35e-2)" 5.7 4.7 5.9 6.7 5.9 5.2 7.6 5.9 6.5 8.1 5.7 6.3 4.4 9.7 9.3 6.0 6.8 4.6 4.5 5.7 5.9 6.2 5.1 5.1 8.9 5.4 5.8 10.4 9.7 5.2 5.9 6.2 5.4 7.2 7.9 6.1 6.0 5.3 6.2 8.4 6.5 7.3 4.8 9.9 6.2 9.8 5.8 6.7 6.9 3.9 8.7 6.9 6.4 6.8 6.0 9.3 15.3 18.5 6.6 10.1 11.9 9.3 7.4 8.5 7.6 10.5 15.7 17.7 8.6 7.2 13.7 14.3 15.9 10.6 11.7 7.3 8.9 31.5 6.6 10.2 9.0 18.5 8.9 7.2 21.0 9.7 28.7 7.3 10.0 14.8 17.1 11.8 11.2 6.3 16.0 25.3 25.2 21.0 12.8 19.2 9.5 6.5 8.3 11.4 11.3 12.6 7.8 9.4 6.2 12.5 17.8 12.8 8.7 16.3 10.5 11.8 9.5 7.6 5.9 12.1 4.3 20.2 10.8 0.0 1.2 0.0 1.7 1.8 1.6 1.6 2.3 2.5 1.9 1.9 2.6 2.4 0.0 1.6 0.7 1.2 2.2 1.7 5.9 5.9 5.9 6.5 5.7 5.9 5.4 5.8 5.4 4.8 5.8 6.8 3.1 6.4 0.5 7.8 3.8 2.9 3.8 1.9 0.6 3.1 3.4 3.2 3.1 2.8 9.7 3.7 0.0 2.2 2.1 1.5 1.9 2.2 5.1 1.4 3.3 3.1 3.0 1.7 8.9 3.5 1.7 2.8 4.6 2.0 3.8 6.0 2.2 1.9 1.8 6.7 8.3 3.9 0.0 2.0 2.0 5.0 1.8 3.1 0.0 3.7 1.6 2.4 1.0 6.6 11.0 3.2 2.4 1.2 3.6 2.5 1.0 1.4 1.3 3.1 6.6 5.0 2.2 14.7 14.5 3.6 3.0 0.8 3.0 3.1 3.2 2.9 ZNF214 ENSG00000149050 "Zinc finger protein 214" Q9UL59 11 6997085-7020346 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 6.6;Endometrial ciliated cells: 6.6;Excitatory neurons: 10.5;Respiratory ciliated cells: 10.4;Spermatocytes: 10.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 3.5" HPA055391 Uncertain Approved Nucleoplasm,Midbody Yes NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm Midbody "HPA055391: AB_2682804" "unprognostic (3.01e-2)" "unprognostic (3.04e-1)" "unprognostic (1.56e-2)" "unprognostic (2.33e-1)" "unprognostic (8.77e-2)" "unprognostic (2.43e-2)" "unprognostic (3.28e-3)" "unprognostic (7.53e-4)" "unprognostic (1.71e-1)" "unprognostic (1.39e-2)" "unprognostic (3.21e-1)" "unprognostic (1.29e-1)" "unprognostic (3.67e-3)" "unprognostic (3.00e-2)" "unprognostic (3.21e-2)" "unprognostic (1.16e-1)" "unprognostic (6.22e-2)" 0.6 1.0 1.0 0.2 1.2 0.0 2.1 0.8 1.5 2.3 1.8 1.2 0.5 2.3 2.7 0.5 3.9 0.8 0.8 0.9 1.1 2.4 1.2 1.2 0.2 1.8 1.7 4.2 1.0 2.5 1.3 0.1 1.1 2.0 1.1 5.3 0.9 2.1 0.4 0.4 0.6 1.7 1.2 0.2 0.7 3.1 1.0 0.2 3.4 0.5 0.2 1.4 1.3 1.4 0.4 0.8 3.3 0.0 0.6 2.2 0.8 1.3 3.5 1.7 1.9 0.0 2.4 0.1 0.4 0.9 1.1 0.5 0.3 0.9 1.9 0.0 0.9 0.0 0.5 0.2 1.2 0.0 0.1 0.6 2.2 0.0 1.9 2.3 1.5 0.0 0.2 0.0 0.6 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 2.2 0.5 0.0 2.6 1.3 0.1 0.1 1.3 0.5 0.0 0.2 1.1 1.4 3.0 0.0 0.0 0.0 0.0 1.9 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.2 0.8 1.5 0.9 1.1 1.8 1.7 1.1 1.2 1.0 1.4 0.5 0.0 1.5 4.6 0.1 0.0 2.0 1.6 0.6 2.5 1.1 1.5 0.9 1.5 2.7 0.0 0.0 0.1 0.0 0.4 1.9 2.1 6.6 6.6 2.0 0.6 2.4 0.0 10.5 0.9 0.4 1.5 0.0 0.9 0.0 1.2 0.0 0.4 0.1 3.3 5.5 1.7 0.0 0.0 0.5 1.0 0.6 0.2 0.0 2.8 0.0 3.0 0.0 4.0 2.9 1.1 0.1 0.4 0.0 0.6 0.8 3.3 10.4 3.6 0.0 0.8 0.9 10.4 3.3 0.9 0.1 0.0 0.2 0.8 0.9 0.4 ZNF263 "FPM315, ZKSCAN12, ZSCAN44" ENSG00000006194 "Zinc finger protein 263" O14978 16 3263800-3301401 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 60.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035085, HPA035086" Approved Supported "Nucleoplasm,Mitotic spindle,Cytosol" Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 51: Non-specific - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol "Nucleoplasm, Mitotic spindle" "HPA035085: AB_10671099, HPA035086: AB_10603244" "unprognostic (2.06e-1)" "unprognostic (2.97e-2)" "unprognostic (2.57e-1)" "unprognostic (1.31e-1)" "unprognostic (3.33e-1)" "unprognostic (2.25e-1)" "unprognostic (6.42e-2)" "unprognostic (7.00e-2)" "unprognostic (1.04e-1)" "unprognostic (1.68e-1)" "unprognostic (6.39e-2)" "unprognostic (2.30e-3)" "unprognostic (2.98e-3)" "unprognostic (5.10e-2)" "unprognostic (1.34e-1)" "unprognostic (3.16e-2)" "unprognostic (2.66e-1)" 20.8 18.3 18.3 16.8 18.1 19.1 24.1 20.4 22.5 20.2 20.3 20.1 14.5 22.9 23.2 15.4 24.5 16.7 15.1 19.1 17.7 20.4 17.6 19.4 22.6 20.1 17.6 29.2 21.5 30.7 23.4 20.4 17.2 21.4 17.0 24.6 20.2 20.2 17.3 24.0 19.3 18.7 16.6 23.2 22.0 18.1 18.2 22.3 20.0 13.7 21.5 19.5 17.5 20.5 19.7 25.1 27.6 40.8 22.7 28.8 36.6 26.1 38.6 30.0 32.2 27.5 30.3 74.2 26.5 33.6 28.6 25.7 38.6 26.4 29.9 41.6 41.3 31.4 35.6 25.6 25.7 48.8 38.5 34.0 53.3 27.6 40.0 33.5 26.2 44.5 37.9 47.4 24.8 25.5 43.9 37.2 55.7 23.2 19.2 70.4 29.8 57.6 20.7 18.4 40.6 43.8 27.9 30.0 30.9 32.5 32.8 57.7 30.1 31.4 30.9 23.3 25.4 50.8 60.8 88.0 12.9 23.6 23.8 1.4 2.5 6.4 3.5 2.4 4.0 2.5 4.2 4.7 3.5 4.4 5.4 3.8 3.0 4.5 3.4 2.9 3.1 1.9 18.3 18.1 20.4 22.5 19.1 17.7 20.1 17.6 17.2 16.6 18.2 20.5 15.9 0.0 11.5 8.8 16.6 17.5 17.1 3.7 16.5 12.5 13.9 12.8 4.6 15.7 5.0 1.8 0.0 11.5 16.1 8.7 7.9 10.2 60.9 10.5 8.8 12.8 13.2 6.3 7.9 10.0 11.1 11.9 11.2 13.5 7.0 14.3 10.0 7.1 9.1 3.3 6.7 12.1 10.2 9.4 14.3 35.1 8.1 9.5 16.0 7.5 8.4 9.8 19.6 8.0 7.8 10.3 6.0 7.9 11.8 16.3 7.5 6.3 5.7 9.0 13.1 17.5 17.3 13.0 11.1 14.3 20.6 11.1 15.0 15.2 12.3 13.6 ZNF302 "ZNF135L, ZNF140L, ZNF327" ENSG00000089335 "Zinc finger protein 302" Q9NR11 19 34677639-34686397 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 203.2;choroid plexus: 142.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA059503 Approved "Vesicles,Cytokinetic bridge" Yes No "Cluster 6: Non-specific - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Vesicles, Cytokinetic bridge" "HPA059503: AB_2684043" "unprognostic (3.52e-1)" "unprognostic (1.85e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (2.03e-5)" "unprognostic (2.25e-1)" "unprognostic (1.32e-2)" "unprognostic (2.78e-1)" "unprognostic (1.50e-2)" "unprognostic (4.33e-3)" "unprognostic (1.82e-2)" "unprognostic (4.63e-2)" "unprognostic (3.39e-2)" "prognostic unfavorable (5.41e-4)" "unprognostic (2.34e-1)" "unprognostic (1.21e-1)" "unprognostic (3.94e-2)" "prognostic favorable (9.85e-5)" 13.7 18.1 139.4 10.2 142.4 4.6 24.0 142.8 203.2 17.5 142.3 20.0 12.4 19.5 21.6 9.1 18.5 11.1 25.4 139.0 140.3 19.8 19.0 14.6 17.8 140.2 141.5 28.0 24.4 21.5 16.7 11.9 141.4 18.0 15.4 45.2 13.5 18.8 37.2 12.8 15.7 14.8 140.7 19.4 14.9 15.5 140.7 17.2 19.1 30.4 16.7 18.0 12.1 147.3 10.5 16.0 33.3 13.2 30.8 23.6 11.6 17.8 21.8 16.0 17.3 11.9 9.5 16.3 21.7 13.5 12.0 8.5 16.3 10.4 17.1 1.3 13.6 31.2 18.0 0.3 16.5 0.3 2.4 22.3 15.0 9.9 1.8 20.0 13.8 11.4 0.3 0.9 25.2 5.5 16.9 16.7 15.1 18.9 10.6 12.5 27.0 9.1 16.9 14.0 14.8 24.1 16.2 6.0 21.9 17.7 12.7 24.8 13.6 7.4 17.6 6.8 8.9 18.6 35.1 5.1 6.8 2.4 33.9 28.1 10.1 17.2 14.9 10.0 20.7 23.3 17.0 14.0 8.8 25.0 28.0 22.3 7.5 19.4 13.4 20.3 14.9 9.1 139.4 142.4 142.8 203.2 139.0 140.3 140.2 141.5 141.4 140.7 140.7 147.3 32.2 28.9 27.6 41.8 33.2 26.8 34.0 16.0 19.9 56.5 24.4 30.9 58.9 25.8 22.1 22.0 52.1 16.8 26.6 10.4 45.0 17.5 31.3 12.7 29.7 34.3 19.9 20.8 41.5 11.4 6.8 41.0 21.4 11.8 29.1 63.0 28.5 11.8 10.1 48.8 42.4 13.4 14.2 14.5 44.9 6.3 59.4 15.7 24.9 29.0 17.8 73.5 42.2 54.8 76.1 10.0 16.4 51.1 14.8 40.1 20.6 14.3 25.6 88.8 52.6 73.5 40.5 67.0 40.2 15.7 21.5 5.5 29.3 44.8 11.6 30.8 ZNF32 "KOX30, Zfp637, ZNF637" ENSG00000169740 "Zinc finger protein 32" P17041 10 43643860-43648881 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 105.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039148 Approved "Nucleoplasm,Nuclear bodies" Yes No "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear bodies" Nucleoplasm "HPA039148: AB_2676365" "unprognostic (1.05e-2)" "unprognostic (2.04e-3)" "unprognostic (1.15e-3)" "unprognostic (9.76e-2)" "unprognostic (1.04e-2)" "unprognostic (5.26e-2)" "prognostic unfavorable (7.08e-4)" "unprognostic (7.39e-2)" "unprognostic (9.94e-3)" "unprognostic (2.90e-3)" "prognostic favorable (3.02e-4)" "unprognostic (1.39e-1)" "unprognostic (5.73e-3)" "unprognostic (6.66e-2)" "unprognostic (4.57e-2)" "unprognostic (2.89e-1)" "unprognostic (1.15e-1)" 33.2 33.2 69.4 13.2 71.9 8.3 45.9 71.0 101.5 46.0 69.0 56.7 12.7 42.9 57.5 23.1 40.0 23.4 60.0 69.0 70.8 49.9 32.4 26.5 22.1 71.3 71.0 52.8 48.1 47.7 45.1 16.6 70.4 48.5 23.4 40.8 31.0 38.1 84.3 31.5 29.6 36.8 70.1 36.0 37.8 16.2 70.9 32.8 41.9 72.9 25.9 41.2 32.9 73.3 25.0 21.8 32.3 48.9 58.1 62.1 10.6 21.9 65.5 39.9 35.8 14.8 12.5 0.1 37.7 46.7 18.8 14.5 20.7 21.2 29.2 27.5 23.0 6.6 13.2 17.2 54.4 0.7 19.7 64.1 48.0 24.7 29.7 38.2 30.6 86.8 19.5 0.0 50.9 22.8 25.2 22.8 25.2 25.2 11.3 38.5 36.3 5.7 40.8 9.7 41.2 36.7 18.1 13.3 35.4 35.3 49.0 23.0 13.1 22.3 26.8 16.4 5.4 14.3 40.2 0.1 8.0 15.9 21.1 14.0 13.9 18.2 36.5 12.9 36.8 26.0 29.2 41.1 22.9 27.2 37.0 41.6 1.1 50.4 11.6 19.3 22.8 20.7 69.4 71.9 71.0 101.5 69.0 70.8 71.3 71.0 70.4 70.1 70.9 73.3 26.1 9.6 14.3 14.0 18.8 11.0 24.4 28.6 33.0 23.2 41.4 57.8 11.7 22.8 16.9 18.4 8.4 18.0 31.9 7.5 105.7 44.7 2.3 16.2 25.6 23.8 27.7 16.8 9.7 47.4 17.1 27.3 16.3 11.5 30.4 34.1 25.7 25.5 29.4 16.8 11.1 16.0 22.4 22.3 10.1 2.1 42.3 19.0 17.8 9.4 15.8 52.7 58.7 16.6 23.0 28.4 10.3 54.5 9.5 36.2 10.0 53.1 12.6 24.1 32.9 38.3 34.2 17.0 14.3 26.4 15.3 6.7 27.1 33.0 17.9 17.9 ZNF341 dJ553F4.3 ENSG00000131061 "Zinc finger protein 341" Q9BYN7 20 33731657-33792269 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 11.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023240, HPA024607, HPA067108" Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles" Yes No "Cluster 34: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles" "Nuclear bodies" "HPA023240: AB_1859207, HPA024607: AB_1859208, HPA067108: AB_2685780" "unprognostic (1.74e-1)" "unprognostic (2.18e-1)" "unprognostic (3.73e-1)" "unprognostic (2.10e-1)" "unprognostic (9.31e-2)" "prognostic favorable (3.93e-4)" "prognostic unfavorable (1.87e-4)" "unprognostic (2.44e-1)" "unprognostic (1.70e-1)" "unprognostic (1.80e-1)" "unprognostic (7.38e-2)" "unprognostic (9.31e-2)" "unprognostic (8.17e-5)" "unprognostic (4.84e-2)" "unprognostic (2.90e-1)" "unprognostic (8.67e-3)" "unprognostic (3.68e-2)" 1.2 0.9 1.0 1.9 1.1 2.4 0.9 0.8 2.2 1.1 0.0 1.5 1.4 1.3 1.0 1.3 1.3 0.9 1.0 1.6 0.2 0.6 0.6 1.1 1.9 0.3 0.1 1.3 1.6 0.9 0.6 1.4 0.4 1.3 1.1 0.7 1.5 1.0 3.3 2.1 1.0 1.2 0.2 1.9 1.4 1.5 0.5 1.8 0.9 3.3 1.2 1.2 1.1 1.3 2.4 6.4 2.2 4.7 2.1 1.7 9.5 2.3 1.2 1.9 1.2 4.6 5.4 3.7 3.8 1.7 2.2 3.7 2.4 4.1 0.8 3.3 2.2 3.6 3.6 3.7 1.2 2.1 4.3 1.4 3.0 1.6 1.0 1.7 2.3 3.4 1.9 1.7 2.0 2.9 1.9 1.6 3.0 3.5 3.1 2.4 1.4 2.1 1.3 5.2 1.9 2.1 6.1 5.6 1.4 1.7 5.0 1.7 2.9 3.4 1.4 2.5 2.2 1.3 1.9 3.4 3.3 1.7 2.4 2.6 1.3 2.9 1.1 1.8 1.0 2.2 0.8 0.7 1.0 1.2 0.5 1.5 2.5 1.3 1.2 0.7 0.6 0.9 1.0 1.1 0.8 2.2 1.6 0.2 0.3 0.1 0.4 0.2 0.5 1.3 1.8 3.2 5.1 5.5 2.9 0.4 1.0 1.5 0.6 2.2 1.9 1.4 2.7 2.8 4.7 1.8 2.1 2.6 0.9 7.0 0.0 1.5 0.6 1.6 1.4 1.4 1.2 0.8 11.3 1.4 3.3 1.6 6.6 2.1 2.5 1.8 1.4 1.0 1.4 1.7 8.0 2.0 2.0 1.6 2.0 0.1 0.6 2.4 0.0 3.7 1.2 0.6 2.1 6.0 7.7 1.7 2.5 0.4 2.6 2.5 4.2 0.4 4.6 2.3 0.0 1.9 1.1 1.6 2.4 1.6 1.0 2.1 1.9 1.5 2.4 2.5 ZNF394 "FLJ12298, ZKSCAN14, ZSCAN46" ENSG00000160908 "Zinc finger protein 394" Q53GI3 7 99473877-99504857 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 97.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051421, HPA054639" Approved Enhanced Nucleoplasm,Cytosol Yes No "Cluster 38: Basophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "HPA051421: AB_2681479, HPA054639: AB_2682553" "prognostic favorable (3.56e-4)" "unprognostic (1.62e-1)" "unprognostic (2.83e-3)" "unprognostic (2.60e-1)" "unprognostic (2.09e-2)" "unprognostic (1.53e-1)" "unprognostic (2.54e-1)" "prognostic favorable (2.11e-4)" "unprognostic (3.62e-2)" "unprognostic (4.14e-1)" "unprognostic (6.28e-2)" "unprognostic (2.45e-1)" "unprognostic (1.59e-1)" "unprognostic (4.70e-2)" "unprognostic (7.47e-2)" "unprognostic (3.42e-1)" "prognostic favorable (1.09e-4)" 13.3 9.6 8.6 10.3 9.5 97.0 12.5 16.4 8.3 11.9 8.8 12.5 10.3 10.4 6.9 12.6 12.5 7.3 12.2 7.7 9.0 10.4 10.1 13.3 13.6 9.8 9.1 13.9 9.7 7.7 9.4 8.1 9.0 13.5 8.6 5.4 10.2 7.7 12.2 15.4 14.3 7.8 8.5 19.2 11.5 10.6 9.4 12.8 10.2 9.6 11.3 11.9 12.2 10.6 10.3 10.2 6.6 14.0 10.4 7.1 13.1 8.5 11.6 9.9 9.7 11.0 11.0 12.4 12.2 9.2 13.5 9.6 9.2 11.2 9.8 9.1 12.0 12.2 12.0 12.1 8.3 17.4 20.0 9.4 9.6 9.6 10.2 7.3 11.6 10.5 17.6 24.0 9.3 19.6 18.3 28.8 15.0 12.9 12.0 10.2 7.3 22.1 11.0 14.7 7.8 16.5 10.2 24.6 16.9 16.5 6.4 21.8 11.9 11.7 12.0 17.4 10.9 19.7 22.1 20.0 8.5 17.4 12.9 56.8 20.6 36.6 31.7 25.5 33.2 24.5 31.8 34.3 22.6 23.6 38.5 30.8 37.8 36.8 26.8 32.8 37.7 24.6 8.6 9.5 16.4 8.3 7.7 9.0 9.8 9.1 9.0 8.5 9.4 10.6 29.3 16.0 19.7 5.2 37.1 35.6 36.1 16.4 16.5 9.7 20.6 14.6 11.4 8.6 16.6 11.0 12.5 15.8 56.7 26.3 17.6 15.7 10.4 17.3 12.9 22.2 20.8 31.5 4.6 14.1 18.2 17.5 25.0 24.4 58.9 17.1 17.5 12.3 18.9 15.2 5.0 16.9 8.2 25.5 29.6 2.9 15.5 29.3 28.4 1.9 19.3 13.6 45.3 7.1 5.6 16.4 20.8 13.5 31.8 29.2 29.7 11.7 19.4 11.7 13.1 22.6 19.7 41.9 30.6 21.5 35.5 29.7 54.3 24.6 18.6 65.6 ZNF410 "APA-1, APA1" ENSG00000119725 "Zinc finger protein 410" Q86VK4 14 73886617-73932521 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 27.7;Excitatory neurons: 22.7;Inhibitory neurons: 23.8;Oligodendrocytes: 31.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002871 Approved "Nuclear bodies" Yes No "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" "Nuclear bodies" "HPA002871: AB_1080712" "unprognostic (5.84e-2)" "unprognostic (5.04e-2)" "unprognostic (9.29e-2)" "unprognostic (6.36e-3)" "unprognostic (5.86e-4)" "unprognostic (4.91e-2)" "unprognostic (2.83e-3)" "unprognostic (2.10e-2)" "unprognostic (1.78e-1)" "unprognostic (1.81e-1)" "unprognostic (1.86e-3)" "unprognostic (1.29e-2)" "unprognostic (3.73e-2)" "unprognostic (2.79e-2)" "unprognostic (2.46e-1)" "unprognostic (3.21e-2)" "unprognostic (1.19e-1)" 29.0 33.0 26.8 18.7 30.4 57.7 29.4 30.9 33.9 30.0 28.9 30.6 19.0 27.5 43.7 33.4 28.1 22.6 21.0 26.3 28.0 33.0 28.8 27.6 25.6 29.1 27.5 38.7 20.6 27.1 27.0 32.2 29.6 29.5 24.4 22.8 24.4 27.3 21.1 37.6 25.2 28.4 26.7 26.1 25.7 44.7 28.3 29.9 24.6 18.3 30.7 29.1 28.7 37.0 46.7 35.8 42.4 45.2 44.8 39.8 52.4 51.4 56.9 88.2 82.0 37.6 40.1 38.4 21.7 65.7 28.2 42.1 42.9 52.8 83.2 56.2 26.9 36.2 31.6 29.9 67.4 30.6 45.6 37.0 72.4 44.5 83.1 39.5 47.5 43.9 38.2 33.0 43.3 88.6 45.8 51.2 15.5 56.3 41.7 40.7 48.5 24.7 57.0 43.7 39.0 50.3 57.2 52.5 54.6 35.5 48.3 52.2 30.7 62.7 59.0 37.1 47.2 45.2 83.4 48.0 40.1 34.1 53.7 65.9 45.3 74.8 47.5 43.1 51.9 37.7 49.0 49.0 45.6 43.0 42.3 43.5 34.4 60.5 50.1 30.8 46.7 55.9 26.8 30.4 30.9 33.9 26.3 28.0 29.1 27.5 29.6 26.7 28.3 37.0 4.3 0.0 3.1 27.7 10.8 0.6 1.5 1.0 10.8 1.5 2.2 1.7 1.1 0.0 2.9 0.0 4.2 1.8 5.0 1.7 0.0 1.0 3.8 4.7 5.6 2.6 0.0 5.9 22.7 0.9 1.5 5.3 10.7 6.7 10.8 2.9 1.8 0.4 1.2 1.7 23.8 1.1 0.0 2.2 3.1 1.1 1.2 5.4 1.8 18.7 1.1 2.4 2.1 18.1 31.0 1.3 1.4 0.4 13.4 1.0 2.4 0.7 0.2 4.7 0.0 4.0 5.1 3.3 1.9 10.1 1.1 2.6 10.5 4.1 0.8 1.4 ZNF426 MGC2663 ENSG00000130818 "Zinc finger protein 426" Q9BUY5 19 9523223-9538645 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029342 Approved Approved Nucleoplasm Yes No "Cluster 44: Non-specific - Transcription" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 36: HEL - Hemostasis" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA029342: AB_10603007" "unprognostic (3.64e-1)" "unprognostic (1.52e-1)" "unprognostic (1.31e-1)" "unprognostic (1.65e-2)" "unprognostic (6.62e-2)" "prognostic favorable (3.74e-4)" "unprognostic (4.34e-2)" "unprognostic (1.77e-2)" "unprognostic (4.75e-3)" "unprognostic (1.05e-3)" "unprognostic (8.89e-3)" "unprognostic (7.41e-3)" "prognostic favorable (2.57e-6)" "unprognostic (1.05e-1)" "unprognostic (3.17e-2)" "unprognostic (2.49e-1)" "prognostic favorable (1.81e-4)" 5.1 3.3 3.1 3.9 4.0 5.7 6.9 5.4 3.4 5.5 4.9 4.1 2.8 7.6 4.5 20.6 5.8 4.3 5.4 3.2 2.9 4.3 2.2 5.1 4.1 3.4 3.4 9.2 4.3 6.3 2.4 5.6 3.4 5.9 3.8 5.1 4.0 5.3 3.7 4.1 2.9 7.8 2.9 4.7 3.7 4.8 3.8 5.7 6.7 5.5 5.7 4.7 5.8 6.0 5.7 1.8 11.2 11.8 7.4 9.7 6.2 7.1 10.8 9.4 11.4 2.4 2.5 5.7 5.6 6.9 6.6 4.8 11.7 8.4 14.0 2.7 9.0 23.7 9.5 4.3 6.7 0.7 7.4 12.4 7.1 10.5 15.0 10.2 10.2 9.7 9.6 0.5 9.1 0.3 13.7 11.4 14.0 1.3 4.4 7.4 13.9 5.9 5.1 14.7 6.3 8.5 12.1 4.3 9.7 9.5 6.0 5.5 8.3 13.2 7.7 6.0 7.7 6.4 9.7 4.8 1.9 0.3 9.6 10.0 3.2 6.1 8.8 4.5 7.8 7.6 6.8 8.7 3.8 6.5 10.0 9.3 6.7 7.8 6.3 3.4 7.1 3.4 3.1 4.0 5.4 3.4 3.2 2.9 3.4 3.4 3.4 2.9 3.8 6.0 15.0 28.9 26.5 3.3 13.2 3.4 15.6 3.2 12.5 24.8 17.1 14.6 10.1 5.7 12.4 7.3 20.9 12.8 13.4 3.8 21.5 10.9 33.5 11.5 14.2 16.4 3.6 12.6 5.4 4.2 10.2 12.4 5.1 15.5 28.4 22.4 14.3 3.0 7.6 37.0 3.9 4.2 12.2 8.9 1.6 8.2 17.1 8.2 3.6 5.6 11.2 20.1 15.5 4.5 4.7 6.9 5.1 22.2 6.7 13.3 4.7 5.4 14.6 22.0 6.6 17.9 13.2 12.2 11.8 14.7 2.8 14.2 12.1 12.3 6.3 17.9 ZNF444 "EZF2, FLJ11137, ZSCAN17" ENSG00000167685 "Zinc finger protein 444" Q8N0Y2 19 56132599-56160893 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 118.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056895, HPA065203" Approved Enhanced Nucleoplasm,Nucleoli Yes No "Cluster 26: Non-specific - Mitochondria" "Cluster 22: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Nucleoli "HPA056895: AB_2683267, HPA065203: AB_2685431" "unprognostic (1.58e-1)" "unprognostic (3.34e-1)" "unprognostic (5.00e-2)" "unprognostic (1.23e-2)" "unprognostic (1.26e-1)" "unprognostic (4.57e-2)" "unprognostic (1.32e-2)" "unprognostic (2.01e-2)" "unprognostic (1.56e-1)" "unprognostic (7.29e-2)" "unprognostic (1.35e-3)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.61e-4)" "unprognostic (4.70e-2)" "unprognostic (1.32e-1)" "unprognostic (1.32e-1)" "prognostic favorable (1.87e-4)" 13.2 23.4 33.8 6.3 31.4 3.2 15.8 28.3 36.3 24.1 31.3 32.5 11.4 24.9 7.7 16.5 26.1 9.3 23.9 30.5 30.2 23.7 64.3 18.1 5.7 38.6 32.4 26.0 46.4 7.8 29.3 4.8 31.4 35.2 4.2 5.7 21.6 19.6 18.6 14.6 19.0 5.9 29.1 17.7 32.0 21.3 32.6 16.0 28.8 7.0 4.4 25.8 17.7 32.1 11.3 21.1 19.0 16.7 8.0 8.1 12.5 14.0 9.2 11.7 12.6 23.1 12.4 19.7 12.2 8.1 5.9 10.3 11.8 9.5 4.9 17.3 118.4 19.6 15.3 42.4 13.0 8.7 17.4 9.5 8.5 9.5 7.3 17.6 10.6 24.1 25.7 8.6 8.3 14.6 28.4 24.4 20.5 22.3 38.2 32.7 12.3 10.7 13.0 10.2 20.4 28.0 7.1 23.2 11.2 10.3 23.2 15.7 14.4 20.8 18.2 4.6 15.6 20.5 18.9 15.1 13.1 11.8 13.9 1.9 1.1 2.4 2.3 0.9 2.5 1.2 4.0 4.0 1.2 2.3 4.0 2.7 0.1 2.2 0.6 2.1 2.9 1.4 33.8 31.4 28.3 36.3 30.5 30.2 38.6 32.4 31.4 29.1 32.6 32.1 12.2 3.2 18.1 26.1 11.0 3.1 17.4 15.3 5.2 17.9 13.9 11.8 13.9 28.6 17.6 11.0 8.4 18.8 5.6 15.6 9.8 26.4 28.6 16.2 8.9 15.1 29.3 6.1 10.0 21.9 9.7 10.0 20.9 9.2 10.2 16.8 18.5 38.9 10.7 20.2 10.0 28.0 20.3 7.2 6.1 39.2 12.2 5.5 16.0 5.6 13.6 17.7 12.3 14.6 19.0 18.3 9.9 12.0 8.6 13.5 18.7 26.9 18.3 13.4 26.3 8.5 12.6 13.6 25.6 3.4 5.3 12.4 11.2 43.4 22.9 11.0 ZNF487 "KRBO1, ZNF487P" ENSG00000243660 "Zinc finger protein 487" 10 43436841-43483181 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 28.2" "Cell type enhanced" "Detected in many" "Early spermatids: 191.2;Endometrial ciliated cells: 65.7;Late spermatids: 289.9;Respiratory ciliated cells: 73.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA037820 Approved "Nucleoplasm,Nuclear membrane,Cytosol" Yes No "Cluster 5: Granulocytes - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA037820: AB_10697083" "unprognostic (1.97e-1)" "unprognostic (1.69e-3)" "unprognostic (1.49e-1)" "unprognostic (3.42e-3)" "unprognostic (7.40e-2)" "unprognostic (1.42e-2)" "unprognostic (7.10e-2)" "unprognostic (4.84e-1)" "unprognostic (4.00e-2)" "unprognostic (1.05e-2)" "unprognostic (6.97e-4)" "unprognostic (5.85e-2)" "unprognostic (3.97e-4)" "unprognostic (2.91e-1)" "unprognostic (4.42e-2)" "unprognostic (2.52e-2)" "unprognostic (5.92e-2)" 2.9 2.1 2.1 2.0 2.1 4.3 2.8 2.0 6.3 3.2 4.5 2.6 2.4 3.8 2.1 2.1 6.0 3.7 2.1 2.3 1.9 2.3 2.2 3.0 2.4 7.5 6.0 4.2 1.6 3.6 2.4 1.9 5.0 2.3 1.9 8.9 1.5 2.7 1.2 2.1 2.5 3.0 4.7 2.4 2.3 28.2 2.2 3.6 3.3 1.6 2.2 3.3 2.1 3.8 1.7 1.6 2.0 2.1 2.4 4.8 0.6 2.7 4.7 2.5 2.7 2.6 4.7 4.3 0.4 3.4 2.4 2.7 0.6 1.0 2.4 0.5 0.9 1.4 0.4 1.5 3.1 1.4 1.7 5.0 2.3 4.2 3.0 5.2 0.9 0.9 0.7 0.6 1.9 3.0 2.9 1.1 0.4 0.8 0.9 1.5 0.7 1.8 5.7 1.9 1.7 1.3 2.4 1.3 1.1 1.2 2.2 1.6 1.5 2.4 1.5 1.4 0.7 0.3 1.1 4.7 5.6 2.0 0.9 1.8 3.0 4.5 3.3 2.2 2.6 1.9 2.4 2.9 3.9 2.5 1.9 2.3 10.4 2.9 1.2 2.9 1.6 2.1 2.1 2.1 2.0 6.3 2.3 1.9 7.5 6.0 5.0 4.7 2.2 3.8 4.0 22.4 4.8 11.8 6.2 1.8 6.3 6.6 3.4 5.4 6.6 7.7 3.3 7.2 8.3 5.5 8.4 1.4 9.8 6.1 11.7 4.5 191.2 65.7 6.5 5.3 7.8 1.3 19.4 2.1 4.0 5.4 5.6 6.3 0.0 3.4 3.3 2.7 3.3 6.7 21.1 4.4 10.2 5.6 3.1 289.9 4.7 6.3 1.8 0.0 7.3 12.6 2.1 6.0 7.1 2.1 3.9 6.8 3.6 3.2 13.0 12.7 73.5 18.7 0.0 6.3 5.1 16.7 7.5 1.9 2.8 1.6 5.6 3.8 3.5 6.1 ZNF518A "KIAA0335, ZNF518" ENSG00000177853 "Zinc finger protein 518A" Q6AHZ1 10 96129715-96205288 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 173.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029049 Approved Nucleoplasm Yes No "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA029049: AB_2672885" "unprognostic (1.48e-1)" "unprognostic (5.24e-2)" "unprognostic (1.70e-2)" "unprognostic (4.66e-2)" "unprognostic (7.61e-2)" "unprognostic (3.38e-3)" "unprognostic (1.21e-1)" "unprognostic (1.07e-1)" "unprognostic (2.73e-2)" "unprognostic (6.02e-1)" "unprognostic (2.97e-1)" "unprognostic (1.09e-3)" "unprognostic (8.38e-3)" "unprognostic (1.43e-1)" "unprognostic (3.06e-1)" "unprognostic (3.09e-2)" "unprognostic (1.16e-3)" 4.1 3.2 3.8 4.4 4.5 7.6 7.3 5.7 4.7 4.3 2.1 7.1 5.0 5.6 7.8 4.3 4.3 4.1 3.4 3.5 5.1 5.1 4.6 4.5 6.1 5.0 4.5 7.4 4.5 4.0 4.1 4.4 5.4 4.8 7.0 9.3 4.1 4.2 1.9 6.0 6.4 4.4 4.5 5.4 6.7 16.1 4.7 8.1 7.7 2.3 6.1 3.8 2.8 6.8 4.2 9.4 10.3 0.0 5.1 5.8 12.4 4.4 2.5 4.7 4.8 8.9 10.0 15.5 4.1 2.8 6.7 5.9 11.8 4.2 4.3 7.1 6.3 23.2 3.2 14.5 4.5 25.3 13.5 3.8 10.1 4.9 7.8 3.4 5.7 17.8 20.1 10.1 4.7 4.2 15.0 15.3 15.9 4.7 0.6 16.7 11.8 6.2 5.6 8.5 3.0 7.2 6.2 5.8 4.5 17.0 6.9 16.0 3.7 2.2 8.5 3.0 4.8 9.3 24.9 8.8 1.5 19.0 2.4 9.8 2.6 3.2 1.8 2.8 2.7 2.5 2.1 1.8 1.7 2.2 3.0 2.1 2.5 2.3 5.3 2.9 2.5 1.4 3.8 4.5 5.7 4.7 3.5 5.1 5.0 4.5 5.4 4.5 4.7 6.8 31.1 57.7 28.2 136.8 26.1 0.0 17.1 0.0 13.1 65.0 32.5 21.2 26.5 30.0 14.9 40.5 43.8 49.1 31.6 51.0 19.6 24.1 23.6 42.6 38.8 24.0 61.2 17.1 63.9 25.5 30.8 21.6 32.6 41.3 9.5 57.9 35.3 28.3 28.1 75.7 90.5 35.8 0.0 32.8 0.0 15.0 35.1 31.3 0.0 81.5 48.7 29.1 47.4 150.3 173.0 32.9 52.4 25.2 18.3 20.8 39.5 20.4 10.2 56.9 19.7 33.8 23.2 73.1 131.2 16.2 0.0 43.8 23.3 40.9 35.2 17.6 ZNF654 "FLJ10997, FLJ21142" ENSG00000175105 "Zinc finger protein 654" 3 88059255-88144660 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 9.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 51.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036172, HPA036173, HPA049262, HPA077939" Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 44: Endometrium - Transcription" Microtubules "Nucleoplasm, Cytokinetic bridge, Mitotic spindle" "HPA036172: AB_10672081, HPA036173: AB_2674987, HPA049262: , HPA077939: AB_2732364" "unprognostic (2.54e-2)" "unprognostic (2.28e-1)" "unprognostic (6.89e-3)" "unprognostic (2.54e-1)" "unprognostic (1.48e-1)" "unprognostic (3.29e-2)" "unprognostic (5.74e-2)" "unprognostic (3.45e-2)" "unprognostic (7.65e-2)" "unprognostic (2.02e-1)" "unprognostic (5.72e-3)" "prognostic unfavorable (9.97e-6)" "unprognostic (1.29e-2)" "unprognostic (2.92e-1)" "unprognostic (1.73e-1)" "unprognostic (2.15e-2)" "unprognostic (2.50e-2)" 5.0 3.7 2.6 4.1 2.7 8.1 5.5 4.9 3.3 5.1 1.8 4.4 4.5 4.6 4.7 5.6 3.4 4.8 3.4 2.4 3.2 4.8 7.0 4.5 6.1 2.8 3.1 6.4 4.1 4.3 1.2 5.0 3.3 5.5 4.2 11.7 4.6 4.1 3.0 6.5 4.8 4.1 3.2 4.9 4.7 6.0 2.7 7.6 5.9 4.9 5.7 5.1 2.3 3.9 7.2 3.0 5.0 6.9 9.9 8.6 4.6 9.3 8.4 6.1 8.4 4.4 4.3 11.3 6.2 7.4 4.4 4.7 5.3 8.6 11.8 7.0 3.0 7.0 3.9 3.2 7.5 8.0 7.6 8.4 7.4 6.7 7.8 12.1 8.1 6.6 4.9 9.0 13.6 5.3 8.0 6.5 2.7 5.7 4.8 5.7 3.4 5.4 5.4 9.0 3.7 3.3 6.8 5.2 17.0 6.0 7.3 5.7 9.5 13.6 8.7 51.8 6.6 10.1 7.6 7.9 10.8 7.5 8.6 9.7 1.2 1.8 1.7 1.2 2.0 1.1 1.8 2.4 1.5 1.7 2.2 1.5 1.7 4.0 1.0 0.7 1.4 1.0 2.6 2.7 4.9 3.3 2.4 3.2 2.8 3.1 3.3 3.2 2.7 3.9 18.2 9.6 13.1 10.1 12.8 22.4 10.1 7.9 9.1 14.0 17.4 10.2 11.8 5.7 10.8 5.5 12.5 4.8 14.5 11.9 1.9 7.6 1.4 9.4 16.0 12.4 5.3 5.2 11.7 5.3 4.2 11.7 5.1 12.2 15.8 14.5 8.9 14.0 6.3 16.8 11.3 7.1 10.2 12.3 19.5 1.5 7.5 14.8 8.8 7.5 10.9 9.9 9.2 9.0 13.3 8.4 8.2 12.4 9.2 12.0 9.0 6.0 10.7 14.3 6.6 13.9 11.5 12.1 10.4 11.4 18.6 8.2 14.0 9.0 7.8 14.4 ZNF672 FLJ22301 ENSG00000171161 "Zinc finger protein 672" Q499Z4 1 248838210-248849517 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 71.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055779, HPA062506" Approved Enhanced Nucleoplasm Yes Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 29: U-266 - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA055779: AB_2682917, HPA062506: AB_2684786" "unprognostic (1.64e-2)" "unprognostic (3.45e-2)" "unprognostic (8.96e-2)" "unprognostic (2.92e-2)" "unprognostic (2.50e-1)" "unprognostic (9.54e-3)" "unprognostic (7.42e-3)" "unprognostic (1.08e-2)" "unprognostic (2.50e-1)" "unprognostic (2.40e-2)" "prognostic favorable (7.51e-4)" "unprognostic (9.03e-2)" "unprognostic (1.16e-2)" "unprognostic (1.99e-2)" "unprognostic (2.69e-1)" "unprognostic (8.35e-3)" "prognostic favorable (1.79e-5)" 13.4 14.8 13.4 11.7 14.8 13.5 13.1 17.9 14.1 13.3 14.6 16.1 11.3 14.3 7.7 19.1 14.9 7.8 30.2 12.8 13.4 22.3 26.1 17.0 14.8 17.2 14.8 11.1 18.0 16.2 17.1 9.3 14.8 24.0 8.4 10.7 17.6 8.2 49.5 17.9 16.8 8.1 14.0 19.8 16.9 16.0 14.9 15.8 20.2 35.7 14.0 16.8 13.7 15.8 19.4 21.5 17.2 19.5 9.4 6.6 33.0 17.8 9.7 12.7 13.6 11.8 19.7 22.0 18.1 11.7 9.6 18.8 9.4 13.3 8.0 32.5 5.3 33.7 20.0 16.0 12.0 14.6 24.4 7.4 10.7 16.6 11.5 10.2 11.7 15.2 41.5 17.6 8.8 13.8 26.8 14.5 20.0 22.3 36.5 49.1 16.3 17.4 12.9 15.6 25.5 22.2 16.0 24.0 15.9 10.2 13.8 30.1 10.0 17.5 10.5 11.6 37.3 52.8 22.2 13.2 16.0 25.1 14.5 9.2 16.3 11.9 8.8 15.9 7.2 11.9 6.3 8.8 24.3 15.0 6.7 6.3 9.2 12.7 15.4 13.6 7.8 14.0 13.4 14.8 17.9 14.1 12.8 13.4 17.2 14.8 14.8 14.0 14.9 15.8 10.7 3.2 15.2 5.9 22.3 13.0 28.2 10.1 6.8 22.0 12.8 9.8 20.2 14.3 8.1 16.5 12.5 32.0 22.0 19.5 21.5 18.3 7.8 9.5 5.7 12.0 18.0 17.0 2.2 10.7 19.9 10.0 10.2 8.9 28.0 12.5 7.5 17.2 16.8 10.1 4.0 17.6 8.2 16.4 16.9 14.6 5.6 20.6 12.4 1.9 17.8 19.5 20.6 2.5 5.2 14.6 19.7 5.7 9.6 21.1 26.5 15.8 9.0 30.5 6.6 17.5 11.7 32.4 23.4 5.5 14.6 71.3 13.5 10.6 16.9 22.5 ZNF678 MGC42493 ENSG00000181450 "Zinc finger protein 678" Q5SXM1 1 227563543-227677443 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 38.2;Oligodendrocytes: 44.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" HPA028507 Uncertain Approved Nucleoli,Mitochondria,Cytosol Yes No "Cluster 41: Basophils - Cellular respiration" "Cluster 34: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoli, Mitochondria, Cytosol" "HPA028507: AB_10603567" "unprognostic (1.76e-2)" "unprognostic (3.01e-2)" "unprognostic (1.68e-1)" "unprognostic (1.39e-1)" "unprognostic (1.20e-2)" "unprognostic (4.42e-3)" "unprognostic (3.92e-2)" "unprognostic (4.64e-2)" "unprognostic (1.59e-2)" "unprognostic (2.19e-2)" "unprognostic (2.50e-1)" "unprognostic (1.64e-1)" "unprognostic (3.54e-6)" "unprognostic (1.39e-1)" "unprognostic (4.18e-1)" "unprognostic (1.10e-1)" "unprognostic (4.88e-4)" 2.5 3.1 2.2 3.0 3.3 3.4 3.7 3.6 2.8 3.6 1.1 2.9 2.3 3.8 2.4 2.1 3.1 3.1 1.9 2.3 4.3 2.6 2.2 3.2 4.4 3.1 2.8 4.0 3.3 2.3 1.5 4.2 2.8 4.0 4.1 5.7 2.7 2.4 1.5 1.4 2.1 2.4 2.3 3.6 3.3 3.9 3.4 4.4 5.4 2.7 4.0 2.1 2.3 5.6 2.5 4.0 13.6 15.5 1.6 3.7 8.3 3.3 3.2 4.8 4.9 3.3 2.9 9.7 8.3 1.5 2.5 4.6 8.3 2.2 7.6 4.2 15.8 4.5 2.9 2.0 3.0 8.0 12.0 3.3 3.8 2.8 6.0 3.5 4.5 10.9 12.4 15.1 5.2 2.0 11.3 2.8 12.1 3.6 6.3 8.4 8.9 3.9 3.4 7.7 5.8 11.2 4.8 5.6 2.3 6.6 7.9 9.2 3.3 5.9 5.5 5.2 6.6 4.8 11.8 10.5 2.3 1.4 6.2 5.4 0.6 0.8 1.3 0.1 1.6 3.7 1.3 0.8 1.2 2.6 1.2 1.7 0.1 1.4 0.4 1.8 1.7 0.8 2.2 3.3 3.6 2.8 2.3 4.3 3.1 2.8 2.8 2.3 3.4 5.6 10.9 3.2 7.3 21.2 7.8 2.3 4.0 2.9 2.2 12.2 5.5 2.9 4.2 4.3 4.5 3.7 4.2 2.1 8.2 6.8 1.9 4.0 0.9 4.6 6.0 6.5 9.6 10.3 11.7 5.2 2.4 6.5 7.1 4.8 3.8 9.4 5.3 3.0 1.8 1.7 17.2 4.8 4.1 3.1 3.7 0.6 7.5 3.3 0.0 17.8 3.3 4.7 5.2 38.2 44.7 3.3 7.3 2.6 5.8 5.4 1.3 1.4 5.5 7.3 0.0 12.3 4.9 7.6 10.5 3.1 0.6 1.4 5.8 4.2 3.8 3.8 ZXDC "FLJ13861, MGC11349" ENSG00000070476 "ZXD family zinc finger C" Q2QGD7 3 126437601-126475891 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 39.4" "Cell type enhanced" "Detected in many" "Astrocytes: 84.5;Oligodendrocyte precursor cells: 67.8;Oligodendrocytes: 99.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.4" "Group enriched" "Detected in many" 4 "dendritic cells: 1.1;granulocytes: 1.7;monocytes: 4.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049593 Approved Nucleoli Yes No "Cluster 14: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoli "HPA049593: AB_2680828" "unprognostic (3.06e-1)" "unprognostic (2.00e-2)" "unprognostic (2.65e-1)" "unprognostic (2.81e-3)" "unprognostic (1.59e-1)" "unprognostic (6.53e-2)" "prognostic unfavorable (2.27e-4)" "unprognostic (3.06e-2)" "unprognostic (5.97e-2)" "unprognostic (4.34e-2)" "unprognostic (3.37e-2)" "unprognostic (2.67e-2)" "unprognostic (1.06e-1)" "unprognostic (8.13e-2)" "unprognostic (2.98e-1)" "unprognostic (4.66e-2)" "unprognostic (1.12e-3)" 6.9 5.2 6.8 6.2 9.4 39.4 6.3 8.7 9.6 8.1 9.2 5.3 5.0 7.8 5.2 7.3 8.8 6.0 5.6 6.6 5.9 6.3 7.6 7.0 7.9 9.6 8.1 10.7 14.9 10.1 3.9 7.5 8.7 7.2 5.4 7.6 8.0 6.6 16.2 9.7 5.9 6.5 6.7 8.8 6.7 6.4 8.3 10.0 8.5 9.8 6.0 6.1 5.6 14.4 15.2 7.6 9.4 8.9 10.1 7.8 16.7 6.7 7.4 9.7 8.6 11.6 6.4 11.2 11.2 6.1 8.9 12.3 12.6 7.9 7.6 6.0 10.8 8.8 9.2 7.7 10.7 13.6 13.7 6.2 15.1 6.0 10.6 9.6 10.0 13.0 9.6 14.6 8.2 8.9 13.1 7.5 13.4 10.0 7.6 14.1 6.4 14.3 6.8 10.9 17.1 9.5 13.0 9.5 18.2 6.2 12.9 11.9 10.2 8.9 11.4 13.4 8.3 12.1 6.1 14.6 9.7 10.5 10.0 1.7 0.4 0.8 0.5 0.2 0.2 0.1 0.3 0.4 0.7 0.4 0.5 0.4 1.2 0.3 4.4 1.1 0.2 0.2 6.8 9.4 8.7 9.6 6.6 5.9 9.6 8.1 8.7 6.7 8.3 14.4 10.1 25.6 15.6 84.5 11.9 6.2 8.3 4.5 10.8 30.1 6.8 6.5 5.5 12.8 7.9 5.5 45.9 7.2 10.0 8.6 7.9 4.8 1.7 8.1 7.9 7.7 3.6 12.0 51.3 6.1 2.6 7.8 9.2 12.2 2.5 16.8 7.9 14.3 5.7 13.5 44.3 6.9 0.0 5.4 4.4 0.8 7.5 9.0 1.8 47.8 7.3 23.0 7.2 67.8 99.2 4.4 5.2 7.5 12.9 6.0 8.4 9.5 7.7 30.4 0.0 13.5 8.9 3.3 9.0 9.0 4.3 6.3 11.1 10.5 6.6 6.3