Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AC087721.2 ENSG00000285920 "Novel protein" 15 41284007-41380996 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Alveolar cells type 1: 6.4;Alveolar cells type 2: 5.3;Club cells: 5.6;granulocytes: 3.8;Respiratory ciliated cells: 2.9" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "HPA042904, HPA074847" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" Yes Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Nucleoli, Nucleoli fibrillar center" "HPA042904: AB_2678220, HPA074847: AB_2732269" 0.8 1.5 0.3 1.8 0.2 2.9 1.3 2.1 1.0 1.0 0.1 1.8 1.7 0.9 0.3 1.6 0.7 1.1 0.8 0.1 0.3 1.1 1.7 1.0 2.4 0.4 0.6 1.5 0.6 0.9 1.3 0.5 0.7 1.9 1.8 0.6 1.1 3.1 1.0 1.4 1.1 0.2 1.6 1.2 2.9 0.6 2.6 0.7 1.9 2.5 1.5 0.4 3.7 1.2 6.6 5.5 2.5 3.7 3.4 3.8 2.9 4.8 4.7 2.0 4.1 2.8 4.0 2.2 4.4 8.7 10.1 5.3 4.1 7.2 3.6 9.4 3.8 3.6 2.0 14.2 8.2 2.1 3.3 3.3 8.8 1.9 4.7 10.6 8.7 11.0 4.3 1.8 5.5 4.5 6.9 9.2 5.5 7.6 5.0 4.3 4.6 4.0 6.6 6.0 6.6 3.9 2.6 7.0 6.6 8.5 4.3 2.8 5.5 3.2 5.8 5.6 10.7 9.4 2.4 8.7 5.6 0.1 0.4 1.0 0.2 0.4 0.3 0.4 0.5 0.4 0.6 0.3 0.2 0.2 0.1 0.3 0.5 0.9 0.9 0.5 0.3 0.2 2.1 1.0 0.1 0.3 0.4 0.6 0.5 0.2 0.6 0.4 0.0 6.4 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 ACD "Pip1, Ptop, Tint1, Tpp1" ENSG00000102977 "ACD shelterin complex subunit and telomerase recruitment factor" Q96AP0 16 67657512-67660815 "Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 71.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049411, HPA057660" Approved Enhanced "Nuclear bodies" NA Yes "Cluster 6: Non-specific - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nuclear bodies" "HPA049411: AB_2680752, HPA057660: AB_2683493" "unprognostic (1.47e-1)" "unprognostic (3.77e-2)" "unprognostic (1.09e-2)" "unprognostic (7.15e-3)" "unprognostic (2.22e-1)" "unprognostic (4.24e-3)" "prognostic unfavorable (2.42e-6)" "unprognostic (1.50e-2)" "unprognostic (4.75e-2)" "unprognostic (2.02e-1)" "unprognostic (1.13e-3)" "unprognostic (3.27e-2)" "unprognostic (8.88e-2)" "unprognostic (6.34e-2)" "unprognostic (2.00e-1)" "unprognostic (1.18e-1)" "unprognostic (3.30e-1)" 13.0 9.9 14.2 7.3 14.4 10.1 12.9 14.4 17.7 17.1 12.0 14.8 4.2 16.4 4.0 9.1 15.6 5.2 11.2 14.6 14.2 10.8 6.7 9.9 10.1 14.6 14.2 19.9 12.4 6.3 13.7 4.7 15.0 12.2 2.3 2.7 9.4 6.3 9.8 11.4 12.1 4.6 14.1 14.9 11.2 23.7 14.6 5.5 10.0 3.2 5.6 15.5 12.2 14.6 42.1 32.3 18.4 19.2 8.3 5.8 39.5 17.1 11.3 25.0 30.3 42.0 20.3 11.6 19.4 9.4 22.5 32.7 11.3 32.8 8.2 12.6 37.4 24.9 13.4 42.4 5.8 32.5 37.6 8.3 10.0 33.7 17.7 9.4 15.9 34.3 15.7 8.1 12.6 45.2 31.8 31.8 23.5 16.3 21.5 44.1 19.8 48.0 10.5 16.6 26.3 23.1 64.0 6.7 14.5 5.3 15.8 17.9 13.8 26.6 22.4 31.9 26.1 21.7 28.6 35.9 24.7 20.5 23.3 34.5 18.2 22.8 40.2 22.2 34.1 46.4 36.7 34.8 21.0 37.7 28.5 30.3 25.9 43.5 25.8 22.9 39.5 24.7 14.2 14.4 14.4 17.7 14.6 14.2 14.6 14.2 15.0 14.1 14.6 14.6 19.4 6.4 11.9 5.5 22.3 14.4 15.9 22.6 21.6 14.7 13.7 16.0 2.8 8.6 12.6 11.0 4.2 25.1 22.5 5.5 9.8 21.3 59.3 6.6 7.7 15.4 12.5 11.6 6.2 19.6 22.8 14.1 9.7 6.8 27.9 13.6 12.8 4.7 15.5 13.5 6.1 6.4 6.1 7.6 20.6 71.4 15.2 13.4 23.2 4.7 19.3 14.3 30.9 4.0 3.6 18.4 9.2 11.7 17.0 9.9 10.2 13.2 16.1 10.8 6.6 11.8 14.8 58.1 24.1 7.1 9.7 11.4 27.0 6.9 9.0 10.0 ADAMTS6 ADAM-TS6 ENSG00000049192 "ADAM metallopeptidase with thrombospondin type 1 motif 6" Q9UKP5 5 65148738-65481920 "Cancer-related genes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 1.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 34.6;Inhibitory neurons: 63.6;Microglial cells: 31.9;Oligodendrocyte precursor cells: 139.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.1;naive B-cell: 1.3" "Lineage enhanced" "Detected in single" "B-cells: 2.1" "Cell line enhanced" "Detected in many" "BJ: 12.6;HBF TERT88: 13.4;hTEC/SVTERT24-B: 12.6;hTERT-HME1: 14.9;TIME: 14.5;U-2197: 16.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043441 Enhanced "Secreted to extracellular matrix" NA Yes "Cluster 37: B-cells - Transcription" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA043441: AB_2678484" "unprognostic (1.53e-1)" "unprognostic (1.40e-1)" "unprognostic (2.70e-3)" "unprognostic (4.33e-2)" "unprognostic (1.03e-2)" "unprognostic (2.39e-2)" "unprognostic (8.24e-2)" "unprognostic (1.65e-2)" "unprognostic (4.77e-2)" "unprognostic (8.04e-2)" "unprognostic (1.56e-1)" "unprognostic (2.13e-1)" "unprognostic (1.13e-6)" "unprognostic (3.23e-5)" "unprognostic (2.09e-1)" "unprognostic (3.02e-4)" "unprognostic (4.18e-3)" 0.5 0.1 0.2 0.6 0.2 0.0 0.3 0.2 0.3 0.3 0.5 0.3 0.1 1.1 0.7 0.2 0.6 1.4 0.3 0.2 0.6 0.2 0.0 0.5 0.4 0.3 0.4 0.3 0.0 0.0 0.1 1.9 0.3 0.2 0.2 0.2 0.1 0.2 0.0 0.1 0.6 0.6 0.3 0.7 0.3 0.5 0.3 0.2 0.1 0.1 0.3 0.7 0.3 0.2 2.7 0.0 0.6 0.6 0.0 2.0 0.0 12.6 7.4 7.7 9.0 0.0 0.3 0.0 0.1 4.8 5.3 0.5 0.1 2.4 13.4 2.0 0.0 0.2 5.1 0.3 0.4 0.0 0.7 0.9 0.0 12.6 14.9 3.7 6.9 1.3 0.0 0.0 4.8 0.0 0.7 0.0 0.1 0.3 0.1 0.4 2.6 0.0 0.0 0.0 0.3 0.5 0.2 0.0 0.0 1.6 0.0 0.1 14.5 3.0 4.5 16.2 10.2 0.1 0.0 0.0 3.4 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.4 2.1 0.1 0.2 0.0 1.3 0.5 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.2 0.3 0.2 0.6 0.3 0.4 0.3 0.3 0.3 0.2 11.3 0.0 0.0 4.9 16.1 0.3 0.0 0.6 0.6 13.9 0.3 0.5 1.8 1.5 0.1 3.7 0.0 34.6 3.2 0.2 0.0 1.4 15.2 8.5 7.4 13.3 0.0 0.0 16.7 0.0 4.7 5.5 0.0 25.7 1.3 18.7 8.9 0.3 2.4 0.0 63.6 0.5 2.0 0.3 1.0 8.0 12.2 3.2 0.0 31.9 0.3 17.4 1.0 139.7 2.1 2.6 0.0 18.0 2.5 0.1 0.1 1.0 0.1 1.1 6.6 5.1 10.5 6.1 8.9 0.3 0.0 14.2 5.1 2.2 0.6 0.0 ADGRE5 "CD97, TM7LN1" ENSG00000123146 "Adhesion G protein-coupled receptor E5" P48960 19 14380501-14408725 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 211.6" "Cell type enhanced" "Detected in many" "dendritic cells: 245.4;Kupffer cells: 111.1;Macrophages: 131.6;NK-cells: 160.6;Plasma cells: 141.5;T-cells: 184.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013707 Enhanced Approved Cytosol "Secreted to blood" NA Yes 10000000 2400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA013707: AB_1846345" "unprognostic (3.16e-1)" "unprognostic (1.80e-1)" "unprognostic (5.10e-2)" "unprognostic (2.30e-1)" "unprognostic (2.85e-2)" "unprognostic (7.24e-2)" "prognostic unfavorable (3.73e-5)" "unprognostic (7.51e-2)" "unprognostic (6.06e-3)" "unprognostic (3.14e-2)" "unprognostic (1.08e-3)" "unprognostic (2.37e-1)" "prognostic unfavorable (1.87e-6)" "unprognostic (2.08e-2)" "unprognostic (4.14e-2)" "unprognostic (2.44e-2)" "unprognostic (6.41e-2)" 45.6 21.4 4.7 79.5 7.6 211.6 21.5 7.8 6.3 60.9 4.0 52.7 43.6 143.6 7.0 15.1 48.9 33.2 30.4 4.8 6.0 28.0 19.9 80.2 58.2 9.6 7.4 14.6 31.4 6.1 7.5 32.7 8.4 17.0 29.7 0.4 22.1 10.4 29.5 14.9 51.0 75.3 6.6 145.0 40.5 3.4 9.0 32.5 21.3 13.5 32.0 42.2 29.3 12.1 118.1 81.9 0.8 77.2 33.3 54.1 12.2 79.6 127.0 56.0 61.0 23.5 115.9 13.5 78.5 103.1 79.6 27.2 21.0 38.8 25.0 73.4 23.7 26.4 113.0 10.4 41.0 57.4 117.3 23.9 1.0 57.1 19.4 18.2 5.6 22.7 35.0 101.9 61.9 26.6 3.7 76.3 2.3 92.7 100.4 7.8 33.7 61.8 18.7 10.4 1.0 2.8 45.4 64.1 57.9 1.8 16.7 52.3 14.0 19.0 31.1 79.5 133.2 0.2 0.4 1.1 67.6 100.4 72.0 371.6 158.5 772.8 187.5 281.4 123.9 28.5 94.2 129.6 102.6 18.5 65.5 91.9 623.2 179.2 352.9 48.4 70.6 242.4 4.7 7.6 7.8 6.3 4.8 6.0 9.6 7.4 8.4 6.6 9.0 12.1 10.0 35.3 93.1 1.3 88.6 0.0 8.5 0.0 2.2 0.5 7.2 6.7 3.7 12.8 17.3 0.0 0.0 4.1 245.4 25.8 0.0 18.1 0.1 16.1 26.9 13.1 4.9 25.7 1.4 22.5 46.3 20.0 49.5 13.3 77.0 1.4 23.9 2.9 50.8 0.0 1.8 25.9 0.0 111.1 0.0 1.4 6.5 131.6 0.0 6.5 55.3 2.6 160.6 2.0 11.2 21.2 30.6 4.9 141.5 12.8 17.8 0.9 27.7 1.5 26.3 34.6 23.1 0.5 5.3 3.2 0.0 7.9 184.3 3.7 29.1 17.6 ADORA2B ENSG00000170425 "Adenosine A2b receptor" P29275 17 15944917-15975746 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.7;urinary bladder: 14.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 73.5;Basal respiratory cells: 75.6;Langerhans cells: 31.9;Suprabasal keratinocytes: 64.4;Urothelial cells: 32.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 14.9;myeloid DC: 9.0" "Group enriched" "Detected in many" 97 "dendritic cells: 9.0;granulocytes: 14.9;monocytes: 5.0" "Cell line enhanced" "Detected in many" "GAMG: 160.8;HMC-1: 162.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073747 Uncertain Cytosol NA Yes "Cluster 10: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA073747: " "unprognostic (6.04e-3)" "unprognostic (1.22e-1)" "unprognostic (8.14e-2)" "unprognostic (1.32e-2)" "unprognostic (4.68e-1)" "unprognostic (7.88e-3)" "unprognostic (2.64e-4)" "unprognostic (1.44e-1)" "unprognostic (1.84e-1)" "unprognostic (1.50e-2)" "unprognostic (2.18e-3)" "unprognostic (1.38e-1)" "unprognostic (1.66e-9)" "unprognostic (2.07e-1)" "unprognostic (3.49e-1)" "unprognostic (1.50e-2)" "unprognostic (2.84e-1)" 0.5 1.1 7.5 1.7 9.4 0.8 0.7 7.0 11.7 2.4 9.0 8.6 0.2 0.7 0.5 9.1 0.9 1.1 1.6 9.1 7.3 0.3 0.1 1.9 0.3 7.7 7.7 0.0 1.3 0.0 1.4 5.0 7.1 1.3 6.6 2.8 1.4 0.1 0.1 8.5 1.3 1.3 6.4 0.2 1.2 0.3 8.3 0.4 0.1 0.5 1.3 14.2 5.2 8.2 34.1 18.3 0.6 0.7 5.8 11.1 0.7 6.4 28.4 18.3 22.6 8.8 34.6 4.4 7.8 5.7 160.8 51.9 7.9 47.8 24.2 9.7 18.0 32.7 5.8 13.0 22.3 0.0 162.6 6.5 20.1 26.0 60.4 31.3 9.3 5.1 1.6 0.1 18.2 8.9 2.2 6.6 1.9 72.0 25.5 0.1 0.4 0.0 19.1 9.1 0.8 1.2 14.3 3.4 9.0 13.4 0.1 5.1 7.7 6.5 17.1 18.3 30.3 2.8 0.0 0.0 25.8 0.0 9.2 14.9 4.2 2.8 0.0 5.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.4 0.0 2.6 0.1 0.0 1.7 7.5 9.4 7.0 11.7 9.1 7.3 7.7 7.7 7.1 6.4 8.3 8.2 0.1 3.2 4.2 18.9 0.2 73.5 21.0 75.6 27.3 0.2 1.3 1.9 0.9 1.5 20.2 0.0 0.0 10.9 0.1 10.8 0.0 6.6 0.9 0.9 0.6 1.7 2.4 3.4 0.9 0.9 3.2 4.9 2.0 1.2 0.0 0.1 2.2 0.0 4.5 0.0 1.1 1.7 2.0 1.4 31.9 0.4 0.0 6.7 7.2 3.7 1.3 7.9 0.0 1.0 1.0 1.0 7.2 0.0 0.0 15.6 0.2 0.0 8.3 0.5 0.0 0.7 2.1 0.5 1.4 23.0 64.4 6.2 0.3 0.3 5.7 32.4 AIMP2 "JTV-1, JTV1, p38, PRO0992" ENSG00000106305 "Aminoacyl tRNA synthetase complex interacting multifunctional protein 2" Q13155 7 6009255-6023834 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Differentiation, Protein biosynthesis" "Developmental protein" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 154.9;tongue: 102.5" "Cell type enhanced" "Detected in all" "Early spermatids: 134.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019098, HPA020057" Supported Approved Cytosol NA Yes 35000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA019098: AB_1852040, HPA020057: AB_1852042" "unprognostic (1.24e-3)" "unprognostic (1.66e-2)" "unprognostic (7.30e-2)" "unprognostic (2.77e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (3.69e-4)" "unprognostic (9.29e-2)" "unprognostic (3.41e-2)" "unprognostic (8.75e-2)" "unprognostic (1.11e-1)" "unprognostic (5.13e-2)" "unprognostic (3.96e-1)" "prognostic favorable (1.38e-5)" "unprognostic (7.44e-2)" "unprognostic (8.97e-2)" "unprognostic (1.26e-2)" "prognostic unfavorable (3.09e-4)" 19.2 21.0 13.6 14.3 15.1 12.4 17.3 15.6 17.0 11.0 12.8 25.8 47.7 16.7 16.7 22.0 14.4 8.8 45.3 15.4 14.6 25.7 33.8 12.6 14.3 14.9 14.5 7.4 17.0 28.7 7.8 13.4 14.7 11.9 24.4 11.9 16.4 15.2 154.9 21.6 27.8 19.3 15.2 13.0 14.6 44.1 15.1 15.4 25.8 102.5 19.5 17.0 13.7 16.2 90.3 100.2 33.1 48.3 34.5 37.3 113.7 49.5 33.3 79.9 59.4 110.1 58.5 109.6 46.2 51.4 90.1 98.6 113.6 74.2 49.6 35.6 84.0 61.2 54.8 84.2 106.2 86.7 53.1 57.4 109.1 72.3 117.9 13.3 60.2 43.8 86.7 35.6 59.4 142.6 37.4 157.2 136.0 44.3 70.4 83.5 73.8 93.3 119.1 41.7 66.1 62.6 50.4 101.3 72.9 41.9 94.5 70.1 51.8 46.0 112.9 77.0 111.2 44.5 73.9 95.5 38.5 122.3 75.6 46.7 61.4 19.5 41.5 77.5 34.9 47.3 27.7 32.5 92.4 31.9 27.1 28.9 6.0 48.3 57.9 58.7 32.3 43.4 13.6 15.1 15.6 17.0 15.4 14.6 14.9 14.5 14.7 15.2 15.1 16.2 15.0 9.6 10.3 8.1 13.0 10.8 22.5 58.5 24.5 10.2 11.8 15.1 2.2 28.6 40.2 12.9 6.2 50.8 10.1 17.6 70.5 52.6 134.7 25.3 23.9 20.0 6.7 24.2 5.8 57.3 64.0 15.1 23.4 20.6 12.6 16.7 13.2 38.8 50.0 6.7 6.7 18.2 57.0 19.1 14.3 84.5 19.9 18.1 19.6 1.9 40.3 17.8 17.5 5.0 10.4 40.1 14.5 18.0 23.8 23.0 59.3 67.7 34.9 11.2 13.1 16.0 24.5 91.1 26.8 37.1 11.6 39.5 12.6 38.0 39.8 17.8 AJUBA "JUB, MGC15563" ENSG00000129474 "Ajuba LIM protein" Q96IF1 14 22971177-22982551 "Cancer-related genes, Predicted intracellular proteins" "Cell adhesion, Cell cycle, RNA-mediated gene silencing, Transcription, Transcription regulation" Repressor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 61.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 47.5;Basal squamous epithelial cells: 35.3;Pancreatic endocrine cells: 33.8;Prostatic glandular cells: 34.2;Sertoli cells: 32.9;Suprabasal keratinocytes: 49.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 217.0;hTCEpi: 222.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA006171 Approved Approved "Nucleoplasm,Golgi apparatus" NA Yes "Cluster 11: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Golgi apparatus" "HPA006171: AB_1852044" "unprognostic (1.15e-1)" "unprognostic (2.99e-2)" "unprognostic (2.39e-1)" "unprognostic (1.24e-3)" "unprognostic (9.81e-2)" "unprognostic (1.49e-1)" "unprognostic (1.80e-3)" "unprognostic (2.73e-1)" "unprognostic (1.39e-1)" "unprognostic (1.86e-1)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.47e-1)" "unprognostic (3.19e-3)" "unprognostic (2.94e-1)" "unprognostic (2.68e-1)" "unprognostic (9.35e-3)" "unprognostic (2.07e-1)" 4.8 3.0 2.3 1.4 1.8 0.5 6.7 2.0 2.2 14.4 9.2 3.2 1.5 12.1 8.5 18.3 7.5 4.9 6.3 2.2 1.5 17.7 43.4 15.2 2.6 2.5 2.1 12.2 11.6 7.2 2.0 19.3 1.6 10.6 2.5 3.7 8.2 15.9 1.9 61.7 1.9 8.4 2.2 3.8 4.2 5.5 1.9 8.2 10.9 2.3 5.5 7.6 15.5 2.7 46.9 54.1 71.0 27.6 6.8 12.2 57.4 44.9 58.5 102.6 91.4 116.0 47.3 1.2 45.5 92.9 70.8 146.2 54.9 217.0 124.6 4.5 5.0 3.5 90.8 131.4 78.9 4.9 3.1 38.9 222.3 42.9 164.3 72.7 40.0 8.3 1.9 2.8 96.2 37.3 4.5 5.7 4.5 86.6 73.9 12.7 59.0 1.2 103.9 71.3 0.2 6.2 135.5 39.4 8.8 57.4 55.3 4.5 36.1 44.2 88.4 7.3 43.6 0.4 1.3 0.5 7.0 4.2 20.6 0.7 0.2 0.1 0.2 0.1 0.1 0.1 0.2 0.5 0.1 0.2 0.3 0.2 0.5 0.5 0.2 0.2 0.0 0.1 2.3 1.8 2.0 2.2 2.2 1.5 2.5 2.1 1.6 2.2 1.9 2.7 2.1 19.2 6.4 0.7 0.0 47.5 13.0 27.6 35.3 0.1 3.7 9.7 4.5 20.0 10.2 7.3 0.0 10.0 0.1 0.3 5.9 14.3 5.8 13.0 2.5 4.0 0.0 0.0 0.0 14.9 9.8 3.4 0.0 4.4 0.0 12.8 2.5 17.1 1.7 0.0 0.0 0.4 2.0 0.0 2.2 5.0 3.7 0.6 3.6 0.0 0.0 8.1 0.0 0.5 0.0 33.8 0.1 0.7 1.2 34.2 0.3 21.0 8.3 0.2 32.9 2.7 14.0 7.0 2.7 14.2 49.6 4.0 0.5 1.6 0.8 18.0 AK4 "AK3, AK3L1" ENSG00000162433 "Adenylate kinase 4" P27144 1 65147549-65232145 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 183.5;liver: 104.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 242.6;Proximal tubular cells: 595.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.1;myeloid DC: 2.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 208.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042753, HPA049461" Enhanced Supported Mitochondria "Intracellular and membrane" NA Yes 39000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA042753: AB_2678146, HPA049461: AB_2680776" "unprognostic (3.73e-2)" "prognostic unfavorable (4.17e-4)" "unprognostic (2.25e-1)" "unprognostic (3.05e-3)" "unprognostic (1.48e-2)" "prognostic unfavorable (8.83e-4)" "unprognostic (1.16e-3)" "unprognostic (3.89e-2)" "unprognostic (4.03e-1)" "unprognostic (5.39e-2)" "prognostic unfavorable (4.34e-5)" "unprognostic (6.71e-2)" "prognostic unfavorable (4.36e-4)" "prognostic unfavorable (4.87e-4)" "unprognostic (2.69e-1)" "unprognostic (7.07e-2)" "unprognostic (7.57e-2)" 24.7 1.9 19.5 6.6 21.0 4.9 26.6 17.8 20.8 6.1 17.5 19.7 4.3 7.0 4.2 23.4 7.6 13.7 51.7 21.4 21.2 183.5 104.0 2.8 1.6 19.0 22.8 4.6 1.2 18.3 4.7 8.3 22.8 16.2 14.0 21.9 9.6 12.7 1.7 27.4 6.6 21.4 18.5 1.2 15.0 11.3 22.7 5.7 2.5 38.8 3.3 19.1 11.8 21.1 73.2 5.0 5.6 23.9 51.6 48.7 12.0 12.1 15.0 25.6 70.8 108.1 8.6 39.1 31.0 19.0 32.1 46.1 18.8 89.9 101.9 33.0 21.5 37.9 21.9 208.6 2.5 29.9 4.6 27.2 49.6 25.1 73.0 42.2 0.9 12.2 48.0 0.6 39.6 31.2 1.1 1.3 24.6 1.0 42.5 0.2 41.0 7.1 37.8 3.2 20.5 15.4 21.6 1.5 16.7 25.8 29.7 12.9 4.2 42.4 36.2 3.3 20.9 39.5 18.8 2.1 68.7 10.9 2.5 0.9 3.1 0.0 0.1 0.6 0.2 0.2 0.1 0.2 2.7 0.1 0.1 0.1 0.4 0.3 0.1 0.4 0.0 0.8 19.5 21.0 17.8 20.8 21.4 21.2 19.0 22.8 22.8 18.5 22.7 21.1 11.2 0.0 0.5 51.2 4.7 49.7 23.6 44.2 63.7 24.5 48.9 44.7 105.7 52.9 14.3 31.3 2.1 2.2 0.6 15.8 56.7 18.6 3.4 30.1 8.2 19.6 5.4 13.9 17.1 12.1 21.1 11.4 27.5 52.2 0.0 36.4 11.7 242.6 3.3 16.8 7.7 8.7 24.4 7.8 9.2 5.8 4.1 6.9 24.9 3.7 5.7 32.7 0.0 9.5 2.5 31.9 4.3 9.4 0.4 38.7 18.8 595.5 12.3 6.5 6.6 5.6 18.8 1.8 9.5 43.1 74.3 4.9 3.6 0.7 23.1 20.4 AKIRIN2 "C6orf166, dJ486L4.2, FLJ10342" ENSG00000135334 "Akirin 2" Q53H80 6 87674860-87702233 "Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" "Developmental protein, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA064239 Supported Nucleoplasm No Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 41: Macrophages - Immune response" Nucleoplasm "HPA064239: AB_2685222" "unprognostic (9.65e-2)" "unprognostic (2.56e-1)" "unprognostic (8.25e-2)" "unprognostic (8.09e-2)" "unprognostic (3.58e-1)" "unprognostic (1.87e-2)" "unprognostic (1.07e-1)" "unprognostic (5.38e-2)" "unprognostic (6.17e-2)" "unprognostic (6.60e-3)" "unprognostic (1.62e-2)" "unprognostic (2.56e-1)" "unprognostic (1.48e-2)" "unprognostic (9.62e-2)" "unprognostic (9.55e-2)" "unprognostic (2.23e-3)" "unprognostic (1.02e-1)" 32.9 37.1 29.0 23.8 32.5 70.5 26.0 26.5 37.6 22.7 27.8 19.8 12.7 24.6 23.7 33.2 22.6 15.3 30.9 34.0 34.0 20.8 31.2 33.2 28.4 26.9 28.8 25.6 13.2 17.8 23.4 18.5 26.4 17.0 12.5 29.7 24.5 11.7 97.4 22.9 22.9 16.4 29.5 49.0 16.8 24.1 35.7 31.2 17.2 42.6 30.3 23.2 25.0 30.9 23.9 24.7 71.0 40.1 43.1 29.6 41.4 41.1 25.7 33.2 32.3 39.7 18.0 62.2 44.1 42.1 55.1 36.2 39.1 29.6 37.9 79.2 48.5 36.3 21.8 89.7 47.1 31.4 30.2 34.6 29.9 41.0 40.2 32.5 36.6 24.3 71.2 42.2 43.5 30.7 9.9 64.9 51.0 20.3 38.1 38.7 50.2 25.7 41.7 20.8 53.0 50.3 24.9 14.8 44.2 40.1 17.9 73.9 47.6 27.5 18.8 23.5 54.6 40.9 48.4 38.8 30.4 40.2 45.1 76.1 57.8 64.8 28.1 73.2 29.2 41.6 27.4 27.6 55.0 32.6 21.4 23.1 144.4 36.6 75.6 75.1 39.1 35.0 29.0 32.5 26.5 37.6 34.0 34.0 26.9 28.8 26.4 29.5 35.7 30.9 49.9 25.6 19.8 10.4 88.2 96.5 192.2 101.9 80.8 13.0 31.8 28.8 22.5 35.8 43.7 18.4 8.4 45.1 94.4 17.1 45.0 30.9 58.0 44.9 34.3 45.6 12.1 45.4 15.6 14.7 71.0 51.1 16.3 39.9 33.6 47.2 44.6 29.9 77.0 11.8 14.8 10.9 69.2 104.4 167.0 100.9 35.8 142.8 74.7 19.7 46.7 80.5 33.0 17.6 15.1 29.6 21.7 28.2 69.4 119.7 19.0 53.5 17.9 17.0 6.6 62.2 39.9 70.6 63.0 92.6 92.9 136.5 99.5 54.2 12.6 191.0 AL031777.2 ENSG00000282988 "Novel protein" 6 26195595-26199293 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 5.1;Extravillous trophoblasts: 6.7;Hofbauer cells: 9.1;Syncytiotrophoblasts: 20.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 16.9;neutrophil: 30.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 30.6" "Cell line enhanced" "Detected in some" "K-562: 6.9;SiHa: 7.7;T-47d: 4.6;U-2 OS: 5.1;U-266/70: 9.3;U-266/84: 5.6" HPA041189 Uncertain Approved Nucleoplasm NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 16: U-266 - Nucleosome" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "HPA041189: AB_2677357" 0.6 0.3 0.5 0.2 0.6 1.5 1.1 1.3 1.2 2.0 1.6 0.7 0.3 0.1 0.0 3.4 0.4 0.1 0.4 0.6 0.5 0.8 1.9 2.2 0.3 1.2 0.8 0.4 0.1 0.1 0.3 0.3 1.1 2.5 0.3 0.1 0.5 0.0 0.0 0.8 0.6 0.1 1.0 2.0 0.5 0.7 1.0 0.8 0.4 0.0 0.1 0.4 2.4 1.4 0.2 0.7 0.2 0.7 1.5 0.1 0.5 0.6 0.1 1.2 0.4 0.2 0.5 0.1 2.0 0.1 0.5 1.4 0.1 0.0 0.2 2.6 0.2 0.4 2.1 0.3 0.1 0.1 0.9 1.0 0.0 0.1 0.3 0.2 0.0 0.6 6.9 1.5 0.0 1.0 0.1 0.4 0.2 2.6 1.6 0.2 0.1 3.0 0.0 0.0 0.6 0.2 7.7 0.5 0.3 0.3 4.6 0.0 0.0 0.7 5.1 0.0 0.0 9.3 5.6 0.7 0.0 1.9 0.7 16.9 0.6 5.1 1.6 0.7 3.6 2.1 0.8 1.1 2.3 4.7 0.8 0.5 30.6 0.9 1.5 5.2 2.3 1.1 0.5 0.6 1.3 1.2 0.6 0.5 1.2 0.8 1.1 1.0 1.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.7 0.0 0.0 0.0 0.0 AMIGO2 "ALI1, DEGA" ENSG00000139211 "Adhesion molecule with Ig like domain 2" Q86SJ2 12 47075707-47079959 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 62.6;Enteroendocrine cells: 60.4;Glandular and luminal cells: 72.8;Granulosa cells: 76.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 192.0;fHDF/TERT166: 183.2;hTERT-RPE1: 312.2;LHCN-M2: 179.2;RT4: 251.9;U-2 OS: 149.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054004, HPA059601" Uncertain Approved "Golgi apparatus,Plasma membrane,Cytosol" NA Yes 390000 "Cluster 32: T-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus, Plasma membrane" Cytosol "HPA054004: AB_2682339, HPA059601: AB_2684078" "unprognostic (2.63e-1)" "unprognostic (6.00e-3)" "unprognostic (1.10e-2)" "unprognostic (3.91e-2)" "unprognostic (3.86e-1)" "unprognostic (1.07e-2)" "unprognostic (3.65e-2)" "unprognostic (1.67e-1)" "unprognostic (3.17e-1)" "unprognostic (3.30e-1)" "prognostic unfavorable (1.80e-4)" "unprognostic (2.98e-2)" "unprognostic (4.87e-2)" "unprognostic (1.16e-2)" "unprognostic (2.95e-1)" "unprognostic (7.47e-2)" "unprognostic (2.29e-3)" 10.8 19.8 4.5 7.0 4.9 3.5 22.8 3.6 5.4 20.3 2.3 39.4 3.3 30.7 7.9 4.0 36.4 19.3 5.6 3.2 8.8 7.7 4.6 20.0 12.4 9.1 37.9 28.7 3.6 6.4 5.3 13.2 19.6 11.3 9.0 25.7 4.5 11.0 1.1 4.4 12.6 34.3 4.3 17.4 5.5 10.7 13.1 2.8 4.2 2.2 7.6 22.6 14.3 3.9 44.4 105.5 6.3 0.2 2.5 0.2 17.2 14.8 39.3 4.7 3.8 0.3 192.0 0.0 47.6 183.2 117.0 64.8 0.0 117.6 5.5 8.6 0.7 0.0 11.0 0.1 3.8 1.2 1.7 0.9 20.1 122.6 59.5 312.2 15.0 0.9 8.5 0.0 179.2 2.1 3.6 0.1 4.5 21.2 27.1 0.3 46.5 0.1 52.3 251.9 18.8 0.0 76.2 9.0 0.5 3.4 11.2 1.0 4.1 2.6 149.9 1.7 121.3 1.9 0.4 0.2 10.0 3.4 2.8 0.0 0.1 0.0 4.4 0.2 6.0 3.7 6.8 6.9 0.7 1.6 15.3 12.1 0.1 8.6 0.0 8.8 4.4 4.7 4.5 4.9 3.6 5.4 3.2 8.8 9.1 37.9 19.6 4.3 13.1 3.9 7.2 9.6 3.1 1.0 3.6 2.4 13.1 39.4 15.4 62.6 10.8 37.7 1.6 1.5 4.9 1.8 0.0 1.0 12.4 0.4 1.9 5.3 1.4 31.5 6.0 12.7 60.4 5.7 2.6 19.3 28.1 11.1 0.5 72.8 7.0 76.8 32.2 1.2 4.8 0.0 0.2 3.1 2.0 3.5 1.1 2.3 2.5 7.2 1.8 1.9 5.3 15.6 2.1 0.0 0.1 40.4 1.5 0.7 3.8 10.7 0.0 0.1 2.9 4.9 0.0 3.2 27.7 0.7 2.4 2.5 0.4 8.5 7.6 12.8 0.3 33.9 ANKRD1 "ALRP, C-193, CARP, CVARP, MCARP" ENSG00000148677 "Ankyrin repeat domain 1" Q15327 10 90912096-90921087 "Metabolic proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "heart muscle: 6540.8" "Cell type enriched" "Detected in some" 15 "Cardiomyocytes: 13820.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 7.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 474.5;EFO-21: 1248.9;hTERT-RPE1: 679.8;LHCN-M2: 1573.6;SuSa: 469.1;TIME: 2206.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA038736 Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center" NA Yes "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoli fibrillar center" Nucleoplasm "HPA038736: AB_2676184" "unprognostic (2.45e-1)" "unprognostic (6.14e-3)" "unprognostic (2.24e-1)" "unprognostic (4.39e-1)" "unprognostic (9.14e-3)" "prognostic unfavorable (1.95e-4)" "unprognostic (1.28e-2)" "unprognostic (6.63e-3)" "unprognostic (2.19e-1)" "unprognostic (3.27e-1)" "unprognostic (4.51e-2)" "unprognostic (3.40e-1)" "unprognostic (2.72e-5)" "unprognostic (3.40e-2)" "unprognostic (2.79e-1)" "unprognostic (7.22e-2)" "unprognostic (3.16e-3)" 0.9 0.7 0.0 0.4 0.0 0.0 1.8 0.2 0.3 0.6 0.6 0.7 0.0 0.4 0.0 0.6 0.1 1.3 6540.8 0.0 0.2 0.7 1.6 48.6 2.5 0.0 0.2 0.7 4.8 0.2 1.1 4.2 0.0 6.8 0.0 0.0 8.7 0.1 571.0 2.3 0.6 2.1 0.0 0.5 1.0 0.9 0.8 1.5 1.7 20.5 0.0 1.2 0.5 0.1 37.2 10.8 6.6 0.3 5.8 6.7 0.5 21.5 2.2 6.0 10.8 474.5 17.9 0.3 1248.9 1.8 48.5 13.3 2.3 3.1 15.7 1.4 1.2 0.2 2.9 148.5 27.7 0.0 0.0 44.2 0.1 9.5 21.6 679.8 437.8 0.0 0.3 0.0 1573.6 0.4 0.0 0.0 1.3 2.7 0.3 0.0 104.3 0.0 3.9 0.5 0.1 0.0 0.3 0.4 1.2 469.1 0.3 1.9 2206.7 4.1 163.9 3.2 175.0 0.0 1.2 3.0 0.9 0.6 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.1 0.0 913.5 42.0 0.0 0.0 0.0 3.5 18.5 0.0 0.0 0.0 0.0 13820.4 7.2 6.6 0.0 0.0 0.6 0.0 0.0 0.0 66.3 5.7 9.4 0.2 83.6 0.0 0.0 0.0 0.2 0.2 243.5 0.0 4.6 3.8 1.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.4 0.0 0.1 1.0 0.0 0.0 74.5 100.9 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.1 ANLN "ANILLIN, scra, Scraps" ENSG00000011426 "Anillin actin binding protein" Q9NQW6 7 36389821-36453791 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 266.0" "Group enriched" "Detected in many" 5 "Early spermatids: 156.4;Oligodendrocytes: 441.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HBF TERT88: 655.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005680, CAB033902, HPA050556, CAB062547, CAB068175" Enhanced Enhanced Nucleoplasm,Midbody Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Midbody "CAB033902: AB_2058302, CAB062547: AB_2665622, CAB068175: AB_2665623, HPA005680: AB_2667388, HPA050556: AB_2681175" "unprognostic (4.23e-2)" "unprognostic (1.59e-3)" "unprognostic (1.49e-1)" "prognostic unfavorable (1.73e-4)" "unprognostic (1.67e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (5.97e-7)" "prognostic unfavorable (6.99e-5)" "unprognostic (2.69e-2)" "unprognostic (3.66e-2)" "prognostic unfavorable (2.00e-6)" "unprognostic (3.13e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.29e-2)" "unprognostic (1.34e-1)" "unprognostic (2.94e-2)" "unprognostic (4.04e-3)" 1.2 0.7 59.8 5.2 134.5 36.4 2.0 125.1 72.7 1.8 18.4 6.0 4.4 1.8 0.2 10.4 0.9 2.1 0.8 59.3 83.6 0.4 1.2 1.4 6.7 162.3 106.5 0.9 0.6 0.2 0.2 8.9 160.2 0.9 8.0 0.3 1.7 0.4 0.3 13.6 4.3 14.9 99.2 1.2 4.8 12.4 102.3 16.0 0.8 0.3 9.5 3.2 3.2 266.0 476.1 96.5 79.3 61.0 10.7 26.9 85.6 292.5 169.3 344.4 256.0 66.4 142.7 23.9 82.1 148.6 182.8 237.0 63.4 170.7 655.4 16.1 46.0 32.7 104.8 55.8 1.7 47.3 36.7 6.0 7.7 225.3 147.2 40.8 109.3 31.2 69.6 48.8 284.4 71.0 40.0 54.8 88.5 71.9 102.3 29.1 238.2 15.9 76.5 76.5 33.5 39.5 154.1 175.8 26.1 109.6 119.0 53.6 104.5 214.2 239.0 127.6 346.6 20.1 34.2 43.2 72.9 74.9 460.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.3 59.8 134.5 125.1 72.7 59.3 83.6 162.3 106.5 160.2 99.2 102.3 266.0 0.4 0.0 1.1 2.3 1.0 14.1 1.9 8.3 7.4 0.0 1.9 2.0 0.6 0.0 3.2 0.0 0.0 13.8 1.1 2.8 0.0 0.7 156.4 18.9 3.2 1.9 0.0 35.3 3.4 0.2 23.2 6.9 10.2 12.8 0.0 15.4 1.1 0.5 9.8 0.0 5.7 3.4 6.1 1.6 5.9 53.3 1.2 2.7 0.0 0.0 0.0 0.0 0.0 1.5 441.3 0.6 0.1 0.0 8.8 1.6 0.8 0.3 10.4 0.0 0.0 0.4 5.2 20.0 17.7 27.1 9.2 2.9 2.6 1.7 6.0 3.3 ANXA1 "ANX1, LPC1" ENSG00000135046 "Annexin A1" P04083 9 73151865-73170393 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" "Phospholipase A2 inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 7527.7" "Cell type enhanced" "Detected in many" "Squamous epithelial cells: 3632.9;Syncytiotrophoblasts: 7071.8;Urothelial cells: 4808.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 2816.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011271, HPA011272, CAB013023, CAB035987, CAB058693" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA Yes 3000000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" Nucleoplasm "CAB013023: AB_2533983, CAB035987: , CAB058693: AB_2665585, HPA011271: AB_1844883, HPA011272: AB_1844884" "unprognostic (2.53e-2)" "unprognostic (1.31e-1)" "unprognostic (9.08e-2)" "prognostic favorable (5.71e-5)" "unprognostic (1.53e-2)" "unprognostic (4.28e-2)" "unprognostic (1.82e-2)" "unprognostic (1.30e-2)" "unprognostic (1.30e-1)" "unprognostic (1.14e-1)" "unprognostic (2.54e-3)" "unprognostic (1.47e-1)" "unprognostic (9.82e-3)" "unprognostic (1.13e-1)" "unprognostic (8.55e-2)" "prognostic favorable (4.57e-5)" "prognostic unfavorable (6.19e-6)" 719.8 60.3 27.5 268.3 35.1 2132.2 442.6 24.8 44.4 952.0 32.8 152.7 64.1 116.2 58.6 7527.7 264.6 329.4 145.3 28.4 53.4 67.9 54.7 470.4 67.9 55.5 46.4 109.4 61.8 28.2 98.1 559.4 36.5 165.3 103.2 6.5 1547.5 154.9 47.6 213.8 88.7 261.5 40.4 79.6 90.2 17.9 45.9 109.9 206.8 89.1 1485.5 386.3 1536.1 43.2 960.2 1485.7 65.8 68.4 905.8 855.6 4.2 1614.6 1008.5 656.3 441.9 43.5 841.0 2.2 520.1 1426.5 1441.9 1147.7 142.6 984.1 516.8 541.6 10.3 73.2 398.5 1.4 719.4 160.9 34.7 495.7 800.6 664.7 1294.6 604.0 947.8 85.4 309.3 39.5 822.6 4.3 287.0 87.7 82.6 379.7 597.6 0.9 369.1 3.2 1495.9 200.4 1.0 0.7 556.6 14.7 377.9 862.7 3.5 24.3 1176.2 761.8 478.9 1058.2 845.1 6.8 2.0 3.6 1757.9 147.8 1171.2 2816.9 1237.6 2227.6 744.1 328.7 757.0 13.7 662.7 664.5 1513.3 3.3 190.7 348.5 128.4 443.6 324.0 53.2 134.5 2021.5 27.5 35.1 24.8 44.4 28.4 53.4 55.5 46.4 36.5 40.4 45.9 43.2 447.4 583.3 415.2 1.6 39.0 846.7 2486.8 2417.6 1748.3 0.1 225.0 417.1 22.5 58.6 2214.7 62.5 0.0 1543.4 602.1 32.2 0.0 167.4 8.2 2037.4 241.6 362.2 5.3 81.2 3.7 23.1 1747.7 732.0 86.6 1993.5 2550.6 0.1 136.7 6.5 593.8 0.0 0.1 20.8 1330.6 545.0 1190.3 7.3 222.4 901.7 307.7 29.0 575.0 0.2 319.3 0.5 0.6 733.2 5.5 9.4 140.4 1552.2 0.1 5.7 1996.9 0.0 65.7 728.2 413.3 2.3 4.0 3632.9 597.7 7071.8 1348.3 3.0 12.6 4808.1 AP1S1 "AP19, CLAPS1, EKV3, SIGMA1A, WUGSC:H_DJ0747G18.2" ENSG00000106367 "Adaptor related protein complex 1 subunit sigma 1" P61966 7 101154456-101161596 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Deafness, Ichthyosis, Mental retardation, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 344.4;Proximal enterocytes: 241.3;Proximal tubular cells: 304.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060945 Supported Supported "Golgi apparatus,Vesicles" NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus, Vesicles" "HPA060945: AB_2684393" "unprognostic (1.98e-2)" "unprognostic (5.41e-3)" "unprognostic (1.02e-1)" "unprognostic (3.34e-2)" "unprognostic (2.98e-3)" "unprognostic (8.70e-3)" "unprognostic (7.06e-3)" "unprognostic (1.12e-1)" "unprognostic (1.76e-1)" "unprognostic (7.79e-2)" "unprognostic (1.34e-1)" "unprognostic (3.75e-2)" "unprognostic (2.81e-2)" "unprognostic (2.14e-2)" "unprognostic (1.74e-1)" "unprognostic (1.49e-1)" "unprognostic (2.75e-1)" 14.4 24.6 72.2 13.9 75.7 5.8 17.2 43.7 82.6 18.3 34.6 28.6 39.0 16.9 17.0 34.2 13.8 12.8 11.8 85.2 59.6 41.2 36.2 14.7 11.9 53.6 51.9 13.5 21.9 22.8 31.0 15.9 53.4 22.2 22.4 14.6 20.3 9.3 6.4 39.2 30.3 12.7 46.1 20.2 22.0 16.4 62.5 19.1 15.2 8.5 13.6 20.1 19.5 62.7 121.0 87.3 63.3 118.4 42.8 70.4 138.2 76.8 51.1 50.8 52.8 47.3 147.5 24.9 127.5 84.6 97.1 59.0 35.3 116.0 45.6 57.0 56.6 16.8 52.0 61.4 54.2 46.8 87.7 79.1 91.0 49.4 20.6 76.7 76.8 54.1 56.7 103.2 129.9 292.1 40.4 107.8 97.8 177.0 188.2 24.9 27.2 54.6 127.8 88.8 47.5 157.7 40.4 121.1 151.4 101.6 50.7 46.8 79.0 74.1 132.3 27.6 55.2 21.4 51.4 48.4 195.2 50.1 152.9 0.5 3.3 0.3 2.3 3.1 2.2 2.6 3.2 2.5 4.6 2.0 1.9 1.8 1.2 1.3 1.8 5.0 3.3 2.4 72.2 75.7 43.7 82.6 85.2 59.6 53.6 51.9 53.4 46.1 62.5 62.7 34.4 6.4 0.0 2.3 17.9 38.7 29.7 173.0 46.7 30.7 54.8 49.0 1.1 45.8 72.9 55.2 8.4 170.7 19.8 88.4 344.4 128.2 2.5 28.8 34.2 36.7 90.3 16.2 21.2 111.7 101.3 27.7 42.8 31.9 5.7 85.3 28.9 43.0 95.2 30.3 10.3 96.5 116.0 24.8 21.6 3.4 35.1 27.3 53.4 7.5 58.0 34.1 17.5 2.5 9.8 183.3 86.1 21.8 17.4 34.9 241.3 304.8 34.9 22.3 19.7 11.4 38.4 13.1 70.9 51.4 45.5 60.5 19.5 157.4 119.9 38.2 APEX2 "APE2, APEXL2, XTH2, ZGRF2" ENSG00000169188 "Apurinic/apyrimidinic endodeoxyribonuclease 2" Q9UBZ4 X 55000363-55009057 "Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair" "DNA-binding, Endonuclease, Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 52.7;Syncytiotrophoblasts: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048577 Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nucleoli fibrillar center" Vesicles "HPA048577: AB_2680448" "unprognostic (2.90e-2)" "prognostic favorable (6.17e-4)" "unprognostic (4.32e-2)" "unprognostic (2.39e-1)" "unprognostic (1.62e-1)" "unprognostic (5.62e-2)" "prognostic unfavorable (6.13e-7)" "unprognostic (5.89e-2)" "unprognostic (4.87e-2)" "prognostic favorable (5.21e-4)" "unprognostic (7.46e-2)" "unprognostic (3.16e-1)" "unprognostic (6.86e-2)" "unprognostic (1.03e-2)" "unprognostic (3.17e-2)" "unprognostic (1.40e-1)" "prognostic favorable (6.63e-4)" 7.2 8.9 6.1 8.8 6.3 10.0 7.2 6.0 6.6 7.6 6.5 8.9 8.9 7.4 8.5 15.5 7.3 6.3 9.0 5.9 6.4 10.8 11.0 7.2 11.3 6.4 6.3 9.6 7.4 7.1 7.0 9.0 6.3 7.8 10.5 2.3 7.0 6.6 7.5 12.2 9.1 7.0 6.3 11.2 7.9 4.1 6.6 10.9 6.3 7.3 13.5 10.2 9.4 6.7 36.9 32.4 12.5 18.3 17.9 11.9 21.3 14.8 19.8 28.0 27.2 17.8 30.0 24.1 22.7 14.0 33.0 26.9 29.1 28.2 21.0 19.7 22.1 29.4 31.6 18.3 11.5 18.3 26.6 11.8 22.6 39.6 14.2 13.2 22.6 25.3 15.4 15.9 21.2 35.7 24.9 23.8 25.0 17.4 38.6 21.8 20.8 26.4 15.2 18.1 11.6 12.7 28.0 33.4 14.7 28.5 26.4 14.1 13.1 16.6 23.9 33.7 19.6 16.4 22.9 19.9 17.7 30.9 20.1 16.2 11.5 13.1 10.2 14.4 8.6 8.2 9.6 10.2 13.7 8.5 8.5 8.4 4.1 42.0 13.4 7.4 11.6 10.1 6.1 6.3 6.0 6.6 5.9 6.4 6.4 6.3 6.3 6.3 6.6 6.7 6.1 3.2 11.8 1.6 12.7 12.9 12.5 20.1 6.8 3.6 7.2 7.1 5.9 15.7 14.9 11.0 0.0 52.7 7.1 17.9 15.6 31.5 0.3 6.0 5.7 11.5 6.1 31.5 0.8 15.1 35.3 7.6 10.2 9.7 8.8 13.1 10.4 11.4 24.2 6.7 0.7 10.1 10.2 10.9 11.1 1.1 5.9 12.0 0.0 1.9 21.7 5.2 16.5 1.0 1.9 20.5 19.1 8.6 9.8 10.5 16.6 21.6 11.8 2.1 19.7 4.4 6.9 1.4 10.6 13.8 12.6 47.6 11.6 12.4 13.7 13.2 ARHGAP11A KIAA0013 ENSG00000198826 "Rho GTPase activating protein 11A" Q6P4F7 15 32615144-32639941 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.2;lymphoid tissue: 26.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 38.7;Extravillous trophoblasts: 23.7;Granulosa cells: 21.1;Plasma cells: 18.6;Spermatocytes: 24.7;Spermatogonia: 22.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040830, HPA066481" Enhanced Approved Nucleoli,Cytosol No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol Nucleoli "HPA040830: AB_10805830, HPA066481: " "unprognostic (5.00e-2)" "unprognostic (5.57e-2)" "unprognostic (6.10e-2)" "unprognostic (1.97e-1)" "unprognostic (2.93e-1)" "unprognostic (3.41e-2)" "prognostic unfavorable (2.05e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (4.87e-2)" "unprognostic (7.71e-2)" "prognostic unfavorable (2.92e-5)" "unprognostic (3.43e-2)" "unprognostic (1.07e-12)" "unprognostic (7.37e-2)" "unprognostic (5.23e-1)" "unprognostic (1.54e-2)" "unprognostic (9.64e-2)" 1.7 0.9 2.0 7.9 2.5 24.2 1.7 2.1 2.1 1.5 1.2 7.5 6.1 1.5 1.0 5.3 0.8 1.7 0.7 1.7 1.9 0.6 1.3 1.7 13.5 2.6 3.0 0.6 2.6 1.2 0.7 4.3 2.6 0.6 8.8 0.5 1.2 0.5 0.9 4.4 7.6 4.8 2.5 2.8 3.6 8.6 2.2 26.1 1.3 0.4 14.3 2.8 1.9 3.0 80.8 69.4 73.1 46.2 5.0 13.0 39.6 78.5 50.2 80.0 63.3 52.2 41.5 43.5 23.7 49.9 91.3 56.9 55.3 43.8 110.9 83.5 27.4 132.6 68.9 33.5 2.0 103.8 55.5 4.3 5.5 61.6 50.9 15.2 61.5 94.4 101.0 112.7 95.3 31.7 58.6 39.7 44.6 71.6 44.5 67.8 141.7 38.2 28.4 41.6 64.7 44.5 72.9 46.2 17.6 37.6 63.6 115.8 35.3 102.5 74.1 42.0 87.2 38.3 63.7 123.7 44.4 129.1 91.8 0.1 0.3 0.8 0.5 0.5 0.2 0.3 1.0 0.9 0.4 0.2 0.4 0.5 0.0 0.1 0.1 0.2 0.8 0.3 2.0 2.5 2.1 2.1 1.7 1.9 2.6 3.0 2.6 2.5 2.2 3.0 0.7 0.0 2.3 0.3 4.6 4.8 1.1 2.4 2.2 0.2 1.3 1.7 0.9 4.3 1.9 1.8 0.0 9.8 2.9 6.2 0.0 0.8 4.7 3.8 2.6 2.0 0.0 38.7 1.0 0.8 23.7 3.5 8.6 2.8 0.0 21.1 1.8 2.1 9.5 0.0 0.6 7.8 0.0 6.5 4.2 5.0 0.6 3.5 0.0 1.0 3.9 0.1 2.1 0.5 1.4 0.5 2.9 0.4 18.6 1.4 1.1 0.4 1.4 1.0 6.6 1.4 3.3 24.7 22.6 10.5 2.3 3.1 5.4 2.0 14.1 2.1 ARHGEF39 "C9orf100, FLJ14642" ENSG00000137135 "Rho guanine nucleotide exchange factor 39" Q8N4T4 9 35658875-35675866 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 98.2;Erythroid cells: 16.6;Extravillous trophoblasts: 19.5;Late spermatids: 36.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Region enriched" "Detected in single" 4 "basal ganglia: 2.7" "Low region specificity" "Detected in all" HPA061299 Uncertain NA Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "HPA061299: AB_2684473" "unprognostic (2.93e-1)" "unprognostic (3.90e-1)" "unprognostic (3.31e-2)" "unprognostic (3.40e-2)" "unprognostic (1.65e-1)" "unprognostic (2.30e-1)" "unprognostic (3.25e-4)" "unprognostic (3.60e-2)" "unprognostic (8.55e-2)" "prognostic favorable (4.48e-4)" "unprognostic (1.14e-1)" "unprognostic (9.75e-2)" "unprognostic (6.04e-9)" "unprognostic (3.31e-3)" "unprognostic (3.38e-1)" "unprognostic (5.14e-2)" "unprognostic (1.46e-1)" 2.9 1.8 0.1 1.6 0.1 1.8 2.2 0.9 0.2 1.8 0.2 4.0 2.1 2.4 0.1 1.5 2.0 0.8 2.2 0.1 0.1 1.2 1.2 1.7 2.0 0.1 0.0 1.1 1.7 0.0 0.9 0.7 0.1 2.5 1.1 1.5 1.0 0.2 0.7 1.3 2.3 0.3 0.0 2.0 3.0 1.1 0.2 1.6 1.2 0.0 1.3 3.0 1.7 0.2 5.2 7.7 7.4 3.6 0.0 0.2 4.9 3.7 1.4 3.3 2.9 8.7 4.0 3.2 2.2 0.5 4.6 3.8 3.7 2.2 1.3 9.5 5.8 5.1 11.3 3.3 0.0 4.3 7.5 0.2 0.2 1.6 0.9 1.0 1.2 4.6 3.6 2.9 1.4 2.6 1.1 2.4 4.7 3.7 2.5 4.4 5.7 1.9 1.2 2.2 5.2 2.1 1.9 4.1 1.0 3.0 6.1 2.5 0.7 2.3 7.4 2.7 2.7 2.8 3.7 1.4 1.4 2.3 5.1 0.3 0.2 0.2 0.5 0.1 0.7 0.1 0.3 0.5 0.2 0.3 0.1 0.3 0.2 0.4 0.2 0.1 0.4 0.1 0.1 0.1 0.9 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.2 0.2 0.7 0.0 0.0 0.0 2.1 2.7 1.4 1.6 0.6 2.1 1.6 3.4 1.4 1.5 1.0 1.8 0.0 8.1 3.6 1.7 0.0 1.0 98.2 0.6 1.6 1.3 3.5 16.6 0.4 0.8 19.5 2.0 14.8 1.1 0.0 4.1 1.8 0.5 5.3 0.0 0.5 4.1 0.0 2.5 5.0 36.1 0.9 2.0 5.4 0.0 0.4 1.6 3.1 0.5 0.3 0.5 0.3 0.4 2.6 1.2 1.5 0.3 1.2 2.4 0.0 2.6 3.3 3.3 5.4 3.5 2.0 1.9 3.1 0.5 6.9 0.8 ARID1A "B120, BAF250, BAF250a, C10rf4, C1orf4, P270, SMARCF1" ENSG00000117713 "AT-rich interaction domain 1A" O14497 1 26693236-26782104 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005456, CAB016334" Supported Enhanced Nucleoplasm NA Yes "Cluster 33: Neutrophils - Chromatin organization" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB016334: AB_673396, HPA005456: AB_1078205" "unprognostic (2.83e-1)" "unprognostic (1.81e-1)" "unprognostic (7.48e-2)" "unprognostic (1.41e-1)" "unprognostic (2.44e-1)" "unprognostic (1.89e-2)" "prognostic unfavorable (4.18e-4)" "unprognostic (3.02e-1)" "unprognostic (3.66e-2)" "unprognostic (1.34e-1)" "unprognostic (9.69e-2)" "unprognostic (7.76e-2)" "unprognostic (1.01e-2)" "unprognostic (1.62e-2)" "unprognostic (6.05e-2)" "unprognostic (2.66e-1)" "unprognostic (6.54e-2)" 16.4 16.3 10.1 22.7 9.4 37.0 16.4 12.9 24.3 16.2 0.0 18.0 15.4 20.4 15.8 22.2 18.3 14.0 17.4 6.3 35.8 13.3 16.8 16.8 25.8 20.8 6.8 20.8 23.2 19.3 14.3 18.6 9.9 15.1 15.3 20.1 19.3 14.4 21.6 20.5 20.3 17.5 3.0 24.3 19.5 16.7 17.9 46.4 22.6 17.6 23.7 18.4 17.8 9.0 53.2 49.5 68.6 71.5 19.6 18.5 32.3 24.4 21.1 32.7 23.0 36.3 34.1 74.3 20.7 31.8 20.7 31.6 60.3 26.9 37.9 92.7 22.6 63.6 33.0 24.7 16.1 95.2 19.6 21.7 18.8 38.7 27.5 18.2 28.6 52.5 77.7 81.1 21.5 25.1 80.1 36.8 72.4 34.5 22.9 82.2 45.3 42.1 20.3 35.3 62.9 50.7 42.7 35.7 29.0 37.8 10.6 53.4 50.6 34.9 33.5 32.4 39.9 38.0 54.9 34.1 21.2 59.8 31.5 0.2 1.5 1.5 1.6 1.2 2.1 1.8 1.3 2.1 1.4 1.6 1.7 1.9 3.3 2.1 1.3 2.4 0.7 1.9 10.1 9.4 12.9 24.3 6.3 35.8 20.8 6.8 9.9 3.0 17.9 9.0 49.9 60.9 40.4 99.9 66.6 73.4 21.0 32.5 90.0 68.0 77.2 61.5 33.0 38.6 35.9 38.6 52.1 36.5 56.1 46.5 1.9 35.3 23.3 48.8 59.3 46.3 47.5 56.6 47.1 37.6 40.2 35.9 35.7 72.3 61.2 68.4 49.6 65.6 51.0 74.0 59.8 50.2 28.5 89.0 47.5 9.0 38.5 73.2 40.9 89.9 86.4 30.8 53.5 78.9 116.1 49.7 36.4 41.8 48.5 50.0 32.4 16.7 36.1 42.3 52.6 38.2 47.3 44.1 52.2 101.8 94.3 36.7 57.0 45.8 52.1 43.2 ARL4A ARL4 ENSG00000122644 "ADP ribosylation factor like GTPase 4A" P40617 7 12686856-12690958 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 191.1" "Group enriched" "Detected in all" 4 "Early spermatids: 1523.0;Late spermatids: 3892.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 261.3;K-562: 328.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064513 Supported Nucleoplasm,Cytosol NA Yes "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 71: Testis - DNA repair" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA064513: AB_2685276" "unprognostic (8.29e-2)" "unprognostic (1.34e-1)" "unprognostic (3.94e-1)" "unprognostic (4.97e-2)" "unprognostic (3.88e-2)" "unprognostic (7.43e-2)" "unprognostic (1.34e-2)" "unprognostic (6.56e-2)" "unprognostic (9.97e-2)" "unprognostic (2.23e-1)" "unprognostic (3.02e-2)" "unprognostic (3.57e-2)" "unprognostic (7.27e-3)" "unprognostic (1.74e-1)" "unprognostic (9.29e-2)" "unprognostic (9.42e-3)" "unprognostic (9.49e-3)" 31.6 7.9 17.1 16.8 20.1 98.4 55.3 14.3 25.8 38.0 22.5 40.7 29.9 16.8 13.8 60.0 27.7 19.2 15.5 23.0 15.4 8.9 15.6 19.4 18.6 14.4 14.3 8.0 7.2 5.3 9.2 23.6 14.5 21.0 34.7 6.7 86.6 16.5 9.1 88.5 62.7 25.1 14.7 21.0 24.5 191.1 15.4 22.7 19.2 8.7 15.9 21.4 63.8 18.6 45.0 46.7 121.5 261.3 19.3 31.8 0.3 17.9 16.2 28.7 17.2 41.6 32.9 0.3 7.5 25.4 73.4 12.6 27.3 22.6 28.9 9.8 20.4 9.2 61.7 39.3 39.8 39.6 16.0 14.3 88.3 16.7 74.2 18.1 69.0 17.7 328.1 42.5 29.4 19.3 2.2 55.6 44.2 129.2 53.1 0.0 42.4 20.8 37.8 21.3 22.3 20.8 29.5 31.1 6.3 31.3 15.3 32.0 24.3 11.5 40.6 43.5 73.1 19.4 27.2 10.3 29.7 16.5 46.4 8.1 14.8 0.7 11.3 25.7 31.7 41.0 26.8 17.7 14.4 44.7 12.9 10.8 2.2 13.0 32.1 12.8 17.8 13.6 17.1 20.1 14.3 25.8 23.0 15.4 14.4 14.3 14.5 14.7 15.4 18.6 134.0 22.4 20.3 1.0 96.9 339.7 179.1 144.5 70.0 20.9 217.9 230.0 15.8 64.3 86.6 20.2 85.5 152.9 61.0 236.6 27.4 47.8 1523.0 179.1 41.5 162.5 62.6 249.9 11.6 29.6 18.7 46.1 63.2 86.5 80.5 27.7 157.1 21.7 59.5 3.3 3.4 107.1 337.7 168.2 171.1 3892.8 69.0 170.9 120.9 17.8 38.7 11.0 3.1 36.7 8.7 55.3 118.0 26.7 24.4 53.4 641.5 14.6 102.5 125.9 13.1 59.5 55.3 564.1 57.5 134.9 234.7 444.0 98.0 32.4 124.2 89.1 ARL6IP1 "AIP1, ARL6IP, ARMER, KIAA0069, SPG61" ENSG00000170540 "ADP ribosylation factor like GTPase 6 interacting protein 1" Q15041 16 18791669-18801572 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045307 Uncertain Approved "Endoplasmic reticulum" NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 12: Non-specific - Cell cycle regulation" "Endoplasmic reticulum" "HPA045307: AB_10961042" "unprognostic (2.42e-1)" "unprognostic (3.47e-2)" "unprognostic (4.07e-3)" "unprognostic (1.12e-1)" "unprognostic (1.54e-1)" "unprognostic (2.60e-3)" "unprognostic (2.58e-2)" "unprognostic (1.76e-2)" "unprognostic (3.88e-2)" "unprognostic (6.83e-2)" "unprognostic (1.91e-3)" "unprognostic (3.33e-2)" "unprognostic (1.13e-2)" "unprognostic (7.09e-2)" "unprognostic (4.60e-2)" "unprognostic (6.32e-3)" "unprognostic (5.36e-3)" 142.0 171.3 206.4 77.7 217.3 209.7 112.9 200.6 282.2 79.2 182.4 140.9 138.8 70.8 122.9 70.0 86.6 131.9 32.1 227.7 209.2 150.1 359.6 79.6 132.6 192.0 197.8 101.6 81.7 180.6 40.7 90.3 200.0 75.9 123.4 316.0 84.3 70.4 23.1 66.1 123.4 69.1 185.0 72.8 125.8 129.9 200.5 158.5 112.5 51.5 113.4 132.5 47.4 197.6 375.3 334.6 417.8 331.6 146.7 93.5 373.2 208.9 196.9 311.0 246.7 205.7 851.1 315.7 388.4 198.0 209.2 388.9 303.7 144.2 359.1 421.2 137.1 227.9 192.5 549.1 116.4 329.9 232.0 78.6 137.7 216.2 224.0 229.1 316.1 180.5 251.0 318.5 607.6 331.4 229.9 238.3 520.0 311.7 109.8 387.9 535.9 266.0 337.8 206.1 255.2 287.5 466.5 279.8 204.5 280.1 576.1 315.9 189.2 204.2 192.9 147.1 384.1 109.5 209.5 383.2 182.8 215.6 405.5 211.4 125.2 84.2 179.4 119.5 167.0 163.2 159.0 199.1 127.4 160.7 137.9 166.4 105.9 179.2 133.3 221.6 281.5 295.0 206.4 217.3 200.6 282.2 227.7 209.2 192.0 197.8 200.0 185.0 200.5 197.6 306.4 67.3 51.0 56.8 170.6 372.6 241.4 170.1 309.6 189.2 256.5 216.8 30.6 361.8 128.7 286.9 131.3 296.7 164.6 269.0 174.1 398.2 74.6 93.3 61.7 188.1 145.9 503.8 70.4 203.1 385.4 150.4 257.9 158.3 135.8 198.0 275.5 457.4 253.9 89.2 94.2 234.6 229.9 275.8 424.6 42.7 84.8 205.8 200.9 39.4 267.3 318.5 142.2 57.3 50.3 271.0 288.5 110.9 107.5 219.4 217.0 189.1 126.6 218.0 92.1 125.6 118.6 193.6 56.6 295.2 326.5 326.6 186.9 53.1 319.7 323.8 ARL6IP6 MGC33864 ENSG00000177917 "ADP ribosylation factor like GTPase 6 interacting protein 6" Q8N6S5 2 152717893-152762396 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 155.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 214.0;eosinophil: 161.8" "Lineage enriched" "Detected in all" 9 "granulocytes: 214.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014743 Approved Approved "Nuclear membrane,Cytosol" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear membrane" Cytosol "HPA014743: AB_1845030" "unprognostic (4.41e-1)" "unprognostic (6.52e-2)" "unprognostic (1.31e-1)" "unprognostic (9.81e-3)" "unprognostic (1.28e-1)" "unprognostic (9.86e-3)" "prognostic unfavorable (1.73e-4)" "unprognostic (5.43e-2)" "unprognostic (2.07e-2)" "unprognostic (2.00e-3)" "unprognostic (4.95e-2)" "unprognostic (1.88e-1)" "prognostic unfavorable (2.14e-4)" "unprognostic (2.14e-1)" "unprognostic (2.67e-1)" "unprognostic (4.57e-1)" "unprognostic (7.39e-2)" 5.1 3.9 3.0 1.8 4.0 8.3 4.7 3.2 3.0 4.4 2.2 3.7 2.4 4.2 1.2 6.0 3.8 1.2 2.7 2.6 3.1 2.5 1.9 4.0 3.4 3.9 3.3 5.0 2.7 1.1 3.1 4.4 4.3 3.1 1.9 3.2 3.9 1.8 3.5 7.1 3.5 1.6 3.6 4.4 3.1 5.3 3.3 3.9 3.2 2.0 2.4 4.2 5.5 5.3 9.6 6.2 13.7 3.9 4.1 4.6 19.7 11.6 4.9 9.6 12.2 14.2 13.3 17.2 10.6 5.2 4.3 10.7 8.1 5.7 10.4 26.1 15.1 14.2 5.3 13.0 4.5 12.1 12.4 3.3 6.5 10.6 8.9 3.4 7.5 11.9 14.9 10.6 7.8 7.1 12.1 12.6 13.3 3.2 12.7 13.0 13.4 13.9 4.5 7.2 11.6 12.0 10.4 1.1 9.7 4.7 4.7 7.9 10.0 14.4 9.9 10.2 10.3 9.9 10.3 13.1 6.8 10.4 12.3 214.0 9.1 161.8 13.2 10.2 13.2 20.3 13.3 13.5 10.9 18.4 13.6 11.4 24.8 9.7 12.8 24.8 19.7 13.2 3.0 4.0 3.2 3.0 2.6 3.1 3.9 3.3 4.3 3.6 3.3 5.3 34.3 16.0 10.0 30.7 41.9 106.6 48.5 74.0 50.7 6.3 20.3 14.9 4.3 17.2 29.9 11.0 4.2 155.7 42.4 14.1 17.6 24.9 14.1 17.7 20.0 31.3 13.8 81.0 21.0 18.6 136.2 27.9 30.1 25.0 27.3 19.4 28.5 5.9 39.8 8.4 23.8 22.2 38.7 24.2 57.2 24.2 19.6 33.6 46.2 30.9 46.2 19.8 32.0 38.7 56.8 22.5 18.6 17.0 33.8 40.3 16.3 8.8 29.2 15.8 32.9 22.2 24.9 24.4 30.0 43.4 106.6 108.4 45.2 27.9 24.5 51.3 ARRDC3 "KIAA1376, TLIMP" ENSG00000113369 "Arrestin domain containing 3" Q96B67 5 91368631-91383317 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 394.2;Syncytiotrophoblasts: 339.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 115.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 20: HeLa - Mitochondria" "Cluster 41: Macrophages - Immune response" "unprognostic (2.28e-1)" "unprognostic (2.24e-1)" "unprognostic (9.42e-2)" "unprognostic (1.28e-1)" "unprognostic (4.07e-2)" "unprognostic (7.36e-2)" "unprognostic (1.57e-3)" "unprognostic (4.91e-2)" "unprognostic (2.44e-1)" "prognostic unfavorable (3.30e-4)" "unprognostic (1.50e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.25e-8)" "prognostic unfavorable (2.26e-4)" "unprognostic (1.34e-1)" "unprognostic (5.74e-2)" "unprognostic (2.15e-1)" 36.8 80.1 16.9 26.8 22.6 167.4 94.6 23.7 32.5 44.8 24.0 19.9 9.9 40.5 27.1 38.7 24.9 39.0 24.7 16.3 20.1 52.7 75.9 44.5 29.3 27.8 20.2 93.2 20.8 54.3 21.5 76.8 22.3 30.3 27.5 75.1 63.9 24.3 34.2 41.3 16.8 33.0 23.8 37.1 25.7 16.6 18.1 28.0 84.0 44.9 28.2 57.0 42.0 41.9 6.6 10.7 12.1 16.6 18.4 31.0 40.2 15.8 14.7 9.3 16.2 5.2 26.9 7.9 13.0 16.2 26.1 14.6 13.4 13.3 8.5 8.2 1.4 3.9 43.3 8.5 14.3 27.9 1.6 13.3 21.2 8.1 20.9 56.4 26.1 7.6 11.5 37.7 14.4 3.7 29.9 4.1 4.3 2.8 11.3 24.8 15.2 41.5 60.4 11.9 21.1 14.0 48.2 3.7 2.9 30.2 17.9 13.1 28.3 7.7 11.2 12.4 9.6 28.6 40.9 16.1 45.8 16.4 8.7 28.7 15.2 20.4 29.1 13.1 21.1 12.3 18.3 22.8 9.3 9.4 24.0 37.7 115.3 14.9 22.2 2.2 21.9 19.9 16.9 22.6 23.7 32.5 16.3 20.1 27.8 20.2 22.3 23.8 18.1 41.9 53.8 51.3 166.5 6.5 47.0 112.0 17.6 51.2 9.1 30.9 89.5 48.5 34.5 20.0 72.4 97.5 31.3 89.9 110.2 21.2 154.6 72.6 27.1 28.9 43.1 143.3 73.0 37.1 10.5 79.5 81.6 95.7 38.7 51.4 37.3 36.4 37.5 155.1 48.7 32.0 15.5 32.4 10.2 106.9 394.2 22.3 21.1 100.3 120.9 14.0 56.6 97.0 50.4 13.6 28.3 41.2 16.1 15.1 58.8 31.2 9.3 57.3 28.5 67.2 19.7 32.1 54.9 8.1 9.6 55.6 118.3 339.4 66.3 23.4 20.2 22.7 ASF1B FLJ10604 ENSG00000105011 "Anti-silencing function 1B histone chaperone" Q9NVP2 19 14119512-14136613 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Chaperone, Chromatin regulator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.2;testis: 32.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 36.1;Early spermatids: 36.4;Erythroid cells: 43.6;Extravillous trophoblasts: 35.4;Spermatocytes: 73.2;Spermatogonia: 87.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 7 "neutrophil: 60.1" "Lineage enriched" "Detected in all" 7 "granulocytes: 60.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA054036, HPA069385" Enhanced Supported Nucleoplasm NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA054036: AB_2682350, HPA069385: " "unprognostic (3.14e-1)" "prognostic favorable (4.45e-5)" "unprognostic (2.41e-3)" "unprognostic (2.40e-1)" "unprognostic (2.15e-1)" "unprognostic (2.27e-2)" "prognostic unfavorable (2.03e-4)" "unprognostic (2.87e-2)" "unprognostic (1.33e-3)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.98e-4)" "unprognostic (8.48e-3)" "prognostic unfavorable (2.22e-16)" "prognostic favorable (2.49e-4)" "unprognostic (1.27e-1)" "unprognostic (3.92e-2)" "unprognostic (4.31e-2)" 0.9 1.4 0.2 5.6 0.3 11.7 1.3 0.3 0.2 2.2 0.1 7.4 5.3 1.0 0.1 10.3 0.7 0.7 0.7 0.1 0.2 1.0 1.3 2.1 12.5 0.3 0.2 0.7 0.7 0.3 0.7 3.6 0.3 0.8 7.7 0.0 1.9 0.3 0.5 3.2 6.0 2.0 0.2 6.7 3.2 32.0 0.3 23.2 0.6 0.4 14.7 1.8 3.2 0.3 64.6 25.3 37.7 28.9 3.8 3.6 16.2 33.1 28.3 63.8 79.5 26.5 31.6 59.1 30.0 17.5 26.5 38.0 41.8 24.1 49.7 54.0 26.9 55.5 48.7 18.6 0.2 39.0 35.1 0.7 1.7 35.8 12.4 7.2 25.1 44.1 50.2 83.8 31.8 75.7 80.8 34.3 17.3 69.1 56.7 77.0 56.0 51.6 20.1 28.3 46.0 16.5 39.8 29.2 17.4 10.3 22.1 41.5 10.6 36.0 21.6 91.0 56.6 43.2 46.5 80.3 28.0 71.9 36.1 0.7 6.2 1.5 1.7 8.0 0.9 1.1 1.5 2.0 1.2 0.9 0.9 1.7 60.1 1.7 8.5 0.5 5.1 3.2 0.2 0.3 0.3 0.2 0.1 0.2 0.3 0.2 0.3 0.2 0.3 0.3 1.0 0.0 0.6 0.3 5.6 2.5 2.4 4.5 1.2 0.1 4.8 8.5 1.2 1.5 1.1 0.0 0.0 36.1 3.8 11.7 0.0 1.0 36.4 2.1 1.3 2.1 1.2 43.6 0.5 1.2 35.4 4.1 23.4 2.3 4.5 9.2 0.4 0.3 21.5 0.0 0.4 9.9 8.2 5.6 5.6 29.1 0.0 5.0 1.8 1.0 2.1 0.3 4.1 0.0 0.5 1.1 2.2 0.7 20.1 1.0 2.4 0.3 0.2 0.9 0.0 1.1 3.3 73.2 87.8 8.3 1.1 10.4 5.3 3.0 20.9 2.4 ASPM "ASP, Calmbp1, FLJ10517, FLJ10549, MCPH5" ENSG00000066279 "Assembly factor for spindle microtubules" Q8IZT6 1 197084121-197146694 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Calmodulin-binding "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 10.1;lymphoid tissue: 17.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 99.5;Granulosa cells: 121.1;Plasma cells: 44.8;Spermatocytes: 43.8;Spermatogonia: 44.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" CAB017816 Approved "Plasma membrane,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "CAB017816: " "unprognostic (3.24e-1)" "unprognostic (1.56e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (3.67e-1)" "unprognostic (3.47e-2)" "prognostic unfavorable (1.25e-4)" "prognostic unfavorable (2.41e-4)" "unprognostic (4.67e-3)" "unprognostic (9.29e-2)" "prognostic unfavorable (2.40e-4)" "unprognostic (1.03e-1)" "unprognostic (0.00e+0)" "unprognostic (7.31e-3)" "unprognostic (1.23e-1)" "unprognostic (4.94e-2)" "unprognostic (3.66e-2)" 0.2 0.1 0.0 3.0 0.0 10.1 0.4 0.0 0.1 0.2 0.0 1.6 2.1 0.3 0.0 1.5 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.3 5.3 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.1 1.9 0.0 0.2 0.0 0.0 2.7 1.9 0.7 0.0 0.9 1.1 3.2 0.1 17.0 0.1 0.0 5.1 0.6 0.4 0.2 44.6 22.9 39.1 23.2 1.9 5.5 14.7 35.1 23.2 32.6 25.6 16.7 31.1 45.4 12.5 27.5 13.8 40.2 33.6 12.1 39.1 41.8 25.4 33.1 56.1 12.8 0.4 51.9 20.5 0.6 1.0 26.1 15.2 7.3 31.5 32.9 41.8 50.7 29.0 16.0 40.6 10.3 17.8 24.8 6.4 30.2 55.5 31.7 7.4 11.4 20.4 29.5 50.6 20.6 9.5 20.8 26.9 12.7 28.9 20.9 20.0 34.9 61.2 13.9 21.6 26.8 14.9 11.0 42.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.6 0.0 1.1 1.3 5.8 6.1 1.5 4.0 2.2 0.1 2.4 2.4 1.1 0.0 1.3 1.8 0.0 20.0 7.8 7.7 0.0 0.3 3.9 2.9 6.2 4.3 0.0 99.5 2.0 0.0 14.8 9.8 13.3 8.1 1.3 121.1 6.4 2.2 11.6 0.0 4.8 6.8 4.1 6.4 2.4 4.5 0.6 6.4 0.0 0.0 0.9 0.7 4.1 0.0 1.0 0.5 0.2 1.5 44.8 2.0 0.4 0.4 0.8 0.3 0.0 0.6 7.0 43.8 44.7 27.1 3.4 3.7 9.1 5.7 16.9 2.1 ATAD2 "ANCCA, CT137, DKFZp667N1320, MGC29843, MGC5254, PRO2000" ENSG00000156802 "ATPase family AAA domain containing 2" Q6PL18 8 123319850-123416350 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 28.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 79.1;Spermatocytes: 106.0;Spermatogonia: 82.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 294.4" "Low region specificity" "Detected in all" "HPA029424, CAB056158" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 33: Neutrophils - Chromatin organization" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB056158: AB_2665580, HPA029424: AB_10611680" "unprognostic (1.56e-1)" "unprognostic (4.55e-2)" "unprognostic (2.07e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.08e-1)" "unprognostic (4.44e-2)" "unprognostic (2.98e-2)" "unprognostic (2.74e-3)" "unprognostic (2.02e-3)" "unprognostic (5.62e-2)" "unprognostic (1.19e-2)" "unprognostic (4.98e-2)" "prognostic unfavorable (8.33e-15)" "unprognostic (1.15e-2)" "unprognostic (1.82e-1)" "unprognostic (4.84e-2)" "unprognostic (6.17e-2)" 2.9 3.4 3.8 7.7 3.6 26.5 6.8 2.6 3.9 12.8 2.0 5.3 5.0 4.3 3.8 6.8 3.4 3.2 5.8 3.2 4.5 1.4 9.9 4.1 14.4 2.9 3.8 7.0 3.3 1.9 3.9 4.8 2.6 10.3 6.9 1.4 4.3 4.7 9.3 6.8 5.2 4.1 2.8 4.9 4.7 18.9 5.1 28.3 3.9 3.2 12.8 4.8 3.9 2.8 103.7 39.6 55.0 19.0 9.7 12.3 24.3 79.2 27.2 66.8 73.9 30.1 43.8 67.2 23.6 25.2 26.5 48.3 74.2 25.6 106.1 94.3 39.0 121.2 41.0 61.4 3.8 44.6 57.4 4.1 3.8 63.6 21.0 14.3 20.7 38.6 57.7 66.4 50.4 107.1 129.5 32.8 10.0 77.8 38.4 66.5 65.6 36.4 23.8 46.7 70.2 30.5 114.4 294.4 20.8 22.1 60.2 41.2 13.0 50.4 69.3 40.2 96.6 21.2 40.7 60.8 32.9 72.9 40.4 5.3 0.8 3.3 1.6 0.8 2.2 2.6 2.3 2.7 1.4 1.5 1.5 1.7 0.2 2.5 1.9 0.1 4.6 1.0 3.8 3.6 2.6 3.9 3.2 4.5 2.9 3.8 2.6 2.8 5.1 2.8 4.8 6.4 11.0 9.4 18.5 15.8 27.9 9.1 14.2 2.8 17.3 21.2 27.3 2.8 10.2 3.7 4.2 14.9 15.3 9.0 1.9 3.5 54.9 7.9 17.3 9.6 1.2 79.1 25.6 2.2 26.2 17.1 13.3 17.5 14.5 37.9 7.1 16.3 11.2 1.7 16.4 13.1 4.1 8.2 6.9 24.4 7.5 11.7 1.8 14.0 6.3 6.3 17.5 11.6 2.8 3.5 4.3 13.9 34.0 20.7 3.1 1.0 5.4 1.9 0.0 9.5 17.5 106.0 82.4 23.7 12.1 13.5 22.8 3.7 14.6 24.5 ATF3 ENSG00000162772 "Activating transcription factor 3" P18847 1 212565334-212620777 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 1462.0;Endometrial ciliated cells: 1049.4;Glandular and luminal cells: 1429.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 6.4;intermediate monocyte: 4.0;myeloid DC: 1.6;non-classical monocyte: 6.3" "Group enriched" "Detected in many" 15 "dendritic cells: 1.6;granulocytes: 6.4;monocytes: 6.3" "Cell line enhanced" "Detected in many" "BEWO: 131.5;HDLM-2: 100.4;SuSa: 155.0" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 9.3" HPA001562 Approved Supported Nucleoplasm,Nucleoli Yes Yes "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nucleoli" "HPA001562: AB_1078233" "unprognostic (2.66e-2)" "unprognostic (1.52e-2)" "unprognostic (2.80e-1)" "unprognostic (4.27e-3)" "unprognostic (3.29e-1)" "unprognostic (1.46e-1)" "unprognostic (1.31e-1)" "unprognostic (1.73e-1)" "unprognostic (9.31e-2)" "unprognostic (8.65e-3)" "unprognostic (8.75e-2)" "unprognostic (1.52e-1)" "unprognostic (6.97e-2)" "unprognostic (3.31e-2)" "unprognostic (1.10e-1)" "unprognostic (2.04e-2)" "unprognostic (2.08e-2)" 176.1 82.8 14.2 63.3 17.7 45.3 97.6 16.5 18.7 106.2 17.1 66.6 21.0 108.6 9.3 128.4 122.6 135.0 113.7 14.4 20.2 98.1 139.9 116.0 20.8 21.1 16.7 40.2 67.2 48.8 45.0 66.3 17.2 116.3 60.0 16.2 33.1 24.1 30.7 154.9 45.6 313.0 15.4 24.4 104.8 3.9 18.8 84.5 181.1 30.0 3.1 281.2 55.2 25.0 21.1 1.2 40.7 8.7 3.9 10.4 131.5 14.7 11.9 12.5 29.8 27.7 15.5 0.4 6.5 0.9 68.0 11.6 24.6 4.0 20.5 100.4 24.6 1.6 11.6 10.0 72.9 9.0 22.7 18.3 65.3 34.9 80.4 2.4 2.6 23.9 10.0 77.0 1.9 2.8 27.5 5.9 29.2 11.5 9.2 8.1 27.1 18.4 1.8 3.0 18.3 18.4 19.1 34.2 59.0 155.0 19.9 6.5 2.4 3.6 19.5 12.3 6.7 60.4 27.9 7.4 11.9 4.8 10.8 6.4 0.7 0.0 0.3 4.0 0.3 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.2 0.0 6.3 0.8 0.0 0.7 14.2 17.7 16.5 18.7 14.4 20.2 21.1 16.7 17.2 15.4 18.8 25.0 568.2 423.1 146.5 1.6 55.3 202.8 866.2 236.1 1462.0 4.4 753.9 510.9 689.3 92.9 136.0 55.2 0.0 178.9 100.3 611.7 1.9 186.2 3.7 1049.4 318.2 176.2 889.6 2.7 2.6 122.7 330.8 452.6 966.9 1429.3 78.6 5.6 30.7 25.8 103.7 1.7 2.4 758.4 114.0 29.8 282.8 2.8 17.4 351.8 174.3 3.7 32.3 39.9 0.0 1.5 10.8 185.7 484.8 1.2 161.0 457.5 421.3 3.3 133.2 5.3 98.6 279.4 573.7 2.2 3.1 474.6 202.7 420.6 97.1 5.8 349.6 263.6 AURKA "AIK, ARK1, AurA, BTAK, PPP1R47, STK15, STK6, STK7" ENSG00000087586 "Aurora kinase A" O14965 20 56369389-56392337 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 22.1;testis: 30.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 81.6;Extravillous trophoblasts: 67.1;granulocytes: 54.1;Spermatocytes: 168.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB001454, HPA002636" Enhanced Approved "Nucleoplasm,Mitotic spindle,Centrosome,Cytosol" Yes Yes "Cluster 7: Monocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Centrosome" "Mitotic spindle, Cytosol" "CAB001454: AB_563420, HPA002636: AB_1845217" "unprognostic (7.73e-2)" "unprognostic (2.46e-2)" "unprognostic (2.76e-2)" "prognostic unfavorable (9.40e-5)" "unprognostic (1.92e-1)" "unprognostic (2.11e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (4.69e-3)" "unprognostic (2.42e-1)" "unprognostic (6.88e-2)" "prognostic unfavorable (6.13e-4)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.47e-8)" "unprognostic (1.67e-1)" "unprognostic (6.83e-2)" "unprognostic (9.00e-2)" "unprognostic (5.14e-2)" 1.3 2.3 1.3 10.4 1.6 15.3 2.2 2.4 1.4 1.4 0.6 10.8 11.7 1.5 0.8 7.5 1.2 2.0 5.3 0.8 1.0 2.3 5.0 2.2 20.9 1.7 1.2 8.4 2.0 1.8 0.6 8.1 1.4 1.1 12.9 3.0 1.9 1.3 8.7 3.5 9.3 4.9 1.3 5.2 4.9 30.8 1.6 20.2 1.4 8.2 22.1 2.9 2.6 1.3 179.9 127.2 84.5 61.2 4.9 10.8 106.3 145.2 66.8 339.7 142.9 361.4 124.8 58.4 96.2 59.2 176.2 142.2 152.4 96.4 360.0 52.4 57.5 102.6 128.9 229.8 2.8 140.4 140.4 5.1 10.1 117.3 104.5 26.7 80.7 93.2 121.8 45.3 146.9 182.1 85.3 108.9 78.3 145.6 129.8 62.9 163.4 65.9 56.0 46.8 73.9 39.6 200.5 228.8 94.2 77.3 137.9 86.1 47.1 149.7 145.3 83.0 208.6 62.3 78.9 100.5 80.5 80.9 127.0 0.2 3.5 4.3 1.2 5.9 1.8 2.5 2.0 1.1 3.7 0.8 0.9 0.9 2.3 1.4 3.4 0.8 4.7 1.7 1.3 1.6 2.4 1.4 0.8 1.0 1.7 1.2 1.4 1.3 1.6 1.3 2.5 0.0 2.8 0.3 7.4 1.1 1.2 5.6 0.6 1.0 4.3 6.2 5.6 1.5 2.3 3.7 2.1 34.5 8.3 8.3 1.9 4.0 33.9 2.0 2.3 3.1 6.0 81.6 1.1 4.9 67.1 7.0 13.7 3.4 54.1 12.3 3.6 2.6 17.5 1.7 1.5 10.8 2.0 3.5 7.6 16.3 1.5 11.7 0.0 1.0 12.0 3.7 3.1 1.0 2.0 5.2 2.8 0.4 10.1 2.0 5.1 4.2 1.5 2.7 6.6 2.2 7.7 168.2 30.8 8.3 1.1 8.2 8.0 8.7 15.5 1.5 AURKB "Aik2, AIM-1, ARK2, AurB, IPL1, PPP1R48, STK12, STK5" ENSG00000178999 "Aurora kinase B" Q96GD4 17 8204733-8210600 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 44.1;lymphoid tissue: 60.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 40.5;Erythroid cells: 59.3;Extravillous trophoblasts: 89.1;Granulosa cells: 24.7;Hofbauer cells: 29.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "T-reg: 7.9" "Group enriched" "Detected in many" 6 "B-cells: 2.5;T-cells: 7.9" "Low cell line specificity" "Detected in many" "Group enriched" "Detected in some" 5 "basal ganglia: 1.3;white matter: 4.0" "Low region specificity" "Detected in all" "CAB005862, HPA037708" Enhanced Enhanced Nucleoplasm,Midbody Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Midbody "CAB005862: AB_449204, HPA037708: AB_2675623" "unprognostic (4.76e-2)" "unprognostic (3.61e-3)" "unprognostic (2.25e-1)" "unprognostic (3.14e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (1.99e-3)" "unprognostic (9.41e-3)" "unprognostic (3.47e-2)" "unprognostic (4.61e-3)" "unprognostic (1.01e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.77e-2)" "unprognostic (2.93e-1)" "unprognostic (6.76e-2)" "unprognostic (3.77e-1)" 1.1 1.2 0.1 14.2 0.2 44.1 1.7 0.2 0.2 3.0 0.1 11.1 12.1 1.6 0.4 18.6 0.6 1.5 0.7 0.1 0.2 0.9 2.0 2.5 36.7 0.1 0.3 0.5 0.6 0.3 0.2 8.2 0.3 0.8 11.0 0.0 2.7 0.3 5.5 9.3 11.6 3.2 0.0 12.0 4.6 1.2 0.4 60.1 0.6 0.0 36.6 3.5 5.9 0.2 196.5 130.9 191.1 93.0 4.2 6.5 73.4 91.7 49.5 186.2 170.6 171.5 57.4 193.3 46.2 37.0 77.0 139.8 140.1 62.6 153.7 84.9 231.3 115.7 78.3 146.1 0.7 62.2 109.2 3.5 2.9 109.4 67.7 18.5 86.5 123.6 73.3 73.4 82.9 92.9 225.1 87.4 119.6 63.9 57.6 149.8 176.1 80.5 41.2 38.2 41.2 59.1 81.7 36.5 61.2 56.5 63.5 41.4 33.9 74.3 75.6 67.6 243.3 53.2 37.7 147.9 35.7 92.9 153.4 0.0 0.4 0.6 0.5 0.3 0.1 1.1 1.3 2.1 0.5 2.5 0.1 0.7 0.9 0.3 0.2 0.2 7.9 0.9 0.1 0.2 0.2 0.2 0.1 0.2 0.1 0.3 0.3 0.0 0.4 0.2 0.3 0.0 0.5 0.0 7.6 4.5 1.8 6.1 0.6 0.0 1.8 2.2 1.4 0.0 2.6 0.0 0.0 40.5 1.8 13.2 0.0 0.4 0.1 0.5 1.6 3.1 0.0 59.3 0.0 0.0 89.1 5.7 6.1 2.1 4.5 24.7 6.1 0.7 29.4 0.0 0.0 10.8 0.0 5.7 7.3 0.2 0.6 5.1 1.8 0.0 0.9 0.0 3.1 0.0 0.1 0.3 2.8 0.0 15.4 1.2 1.5 0.1 0.2 0.0 0.0 0.1 4.8 1.6 7.2 11.8 2.4 9.0 4.3 1.0 22.0 2.8 AXL "ARK, JTK11, Tyro7, UFO" ENSG00000167601 "AXL receptor tyrosine kinase" P30530 19 41219223-41261766 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Differentiation, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Oncogene, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 147.2;Kupffer cells: 187.5;Langerhans cells: 185.5;Prostatic glandular cells: 123.4;Sertoli cells: 210.4;Smooth muscle cells: 171.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 11.1;plasmacytoid DC: 25.7" "Group enriched" "Detected in many" 12 "dendritic cells: 25.7;NK-cells: 11.1" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 501.2;U-251 MG: 540.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032501, HPA037422, HPA037423, HPA075217" Uncertain Supported "Vesicles,Plasma membrane,Actin filaments" NA Yes 12100000 72000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "Vesicles, Actin filaments" "CAB032501: AB_2062572, HPA037422: AB_10672347, HPA037423: AB_2675470, HPA075217: " "unprognostic (2.20e-1)" "unprognostic (2.02e-1)" "unprognostic (6.79e-3)" "unprognostic (1.01e-1)" "unprognostic (1.40e-1)" "unprognostic (8.49e-3)" "unprognostic (2.42e-1)" "unprognostic (1.74e-1)" "unprognostic (3.15e-2)" "unprognostic (2.82e-2)" "unprognostic (9.57e-3)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.53e-7)" "unprognostic (1.16e-3)" "unprognostic (1.52e-2)" "unprognostic (5.56e-2)" "unprognostic (4.83e-3)" 43.6 18.8 17.5 15.5 22.6 1.7 26.6 19.7 17.7 36.1 12.4 42.5 11.7 34.4 8.7 17.6 25.4 22.4 26.7 16.6 18.8 9.8 15.0 25.9 6.2 26.8 20.6 24.7 6.3 10.7 7.3 34.2 22.1 19.2 12.6 5.8 10.6 24.6 9.4 20.0 19.0 37.1 20.9 37.7 21.4 18.6 24.0 7.2 16.6 11.3 5.0 32.5 25.2 21.9 408.0 160.0 9.7 1.3 34.6 34.7 0.5 314.5 280.2 450.9 278.2 8.5 185.5 0.2 124.7 501.2 235.3 33.3 0.4 211.8 384.8 0.7 0.3 0.0 100.4 6.3 125.0 0.3 0.3 26.4 3.8 266.7 409.5 254.8 169.8 0.1 15.8 0.5 284.6 0.5 0.2 0.4 4.1 1.0 76.3 0.2 165.3 0.3 202.3 0.2 0.1 0.1 81.5 0.6 1.8 57.4 0.9 7.2 351.8 317.8 214.6 307.7 540.8 0.5 0.9 1.0 211.5 0.5 241.8 1.5 0.3 0.2 0.1 0.4 0.2 0.1 0.3 0.1 6.0 0.1 0.3 0.3 0.3 11.1 0.2 25.7 0.4 0.3 17.5 22.6 19.7 17.7 16.6 18.8 26.8 20.6 22.1 20.9 24.0 21.9 13.5 9.6 3.6 35.9 1.9 41.7 88.3 10.3 3.4 0.5 2.3 14.2 8.6 1.5 4.4 5.5 0.0 4.2 0.8 0.1 0.0 6.9 8.7 6.0 45.8 17.7 0.0 0.0 0.8 0.2 2.1 147.2 1.5 5.4 0.0 17.3 11.0 1.2 28.8 1.7 1.1 0.1 2.0 187.5 185.5 5.5 61.5 61.4 26.6 30.9 3.1 26.8 0.0 11.1 0.5 14.5 0.1 79.7 0.8 123.4 0.3 0.1 2.8 1.2 210.4 38.1 171.1 1.9 2.0 1.2 29.1 11.5 3.6 2.5 0.1 28.0 BARD1 ENSG00000138376 "BRCA1 associated RING domain 1" Q99728 2 214725646-214809683 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 68.6;Basal prostatic cells: 62.2;Suprabasal keratinocytes: 74.4;Urothelial cells: 67.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034106, HPA035354, HPA044864" Enhanced Supported "Nucleoplasm,Nuclear speckles,Cytoplasmic bodies" No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Nuclear speckles" "Cytoplasmic bodies" "CAB034106: AB_2061237, HPA035354: AB_2674585, HPA044864: AB_2679119" "unprognostic (4.85e-2)" "unprognostic (1.87e-2)" "unprognostic (1.74e-2)" "unprognostic (8.37e-3)" "unprognostic (2.57e-2)" "unprognostic (1.03e-2)" "unprognostic (6.25e-4)" "unprognostic (1.99e-1)" "unprognostic (2.16e-2)" "unprognostic (3.92e-3)" "unprognostic (2.80e-2)" "unprognostic (7.41e-2)" "unprognostic (1.94e-8)" "unprognostic (3.94e-2)" "unprognostic (2.28e-1)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" 1.8 0.6 3.0 2.7 4.6 11.4 2.9 2.2 2.7 3.1 0.2 2.9 2.3 3.3 2.6 5.1 1.9 2.0 1.5 2.3 4.1 0.8 1.0 2.5 5.5 3.8 3.2 2.3 1.6 2.3 1.2 2.3 3.9 2.9 3.6 2.0 1.9 3.6 4.2 8.8 2.1 3.9 3.9 2.6 1.9 6.6 4.1 7.0 1.4 2.3 6.6 2.1 3.8 4.2 12.3 8.8 20.2 9.3 2.7 4.0 12.0 17.3 10.6 17.8 21.8 12.0 12.2 12.6 7.6 8.5 9.5 12.7 16.5 10.5 22.7 11.5 6.4 12.5 13.8 8.7 0.9 13.9 12.7 4.7 1.1 15.0 8.1 4.5 6.1 14.7 7.9 36.0 13.7 10.7 27.9 12.5 14.3 7.9 3.7 24.7 19.8 11.2 3.9 14.0 5.8 8.8 15.0 14.7 5.3 10.9 16.3 13.4 4.7 18.0 14.0 11.7 13.6 10.2 12.6 28.0 7.6 11.3 13.4 3.9 2.0 5.8 4.6 4.0 3.2 9.7 5.4 5.5 3.6 8.2 2.4 4.0 0.3 7.3 3.8 6.9 17.1 2.3 3.0 4.6 2.2 2.7 2.3 4.1 3.8 3.2 3.9 3.9 4.1 4.2 12.3 6.4 2.2 14.7 13.0 68.6 62.2 13.0 14.2 3.3 9.9 14.1 17.4 17.2 12.7 9.2 0.0 18.2 11.3 8.2 3.9 8.0 9.2 13.3 11.9 9.6 1.2 34.5 5.5 6.9 16.0 10.0 10.2 18.0 15.2 28.2 10.0 4.2 12.5 1.7 15.4 13.1 8.2 10.1 12.2 5.7 6.2 11.2 3.6 15.9 16.6 4.4 9.2 19.6 31.7 6.5 6.5 10.1 22.0 22.9 3.2 0.7 12.3 6.8 19.7 15.4 16.9 27.6 43.4 28.6 74.4 5.1 13.4 10.5 14.7 67.2 BDNF ENSG00000176697 "Brain derived neurotrophic factor" P23560 11 27654893-27722058 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 38.5;Bipolar cells: 13.8;Cardiomyocytes: 9.1;Excitatory neurons: 22.3;Smooth muscle cells: 25.8;Theca cells: 9.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 36.6;BJ hTERT+ SV40 Large T+: 28.0;BJ hTERT+ SV40 Large T+ RasG12V: 20.9;HBF TERT88: 26.5;U-138 MG: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB009564, HPA031440, HPA056104" Enhanced Supported "Nuclear speckles,Mitochondria" "Secreted to blood" NA Yes 16000000 24000 "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Mitochondria" "CAB009564: AB_2064213, HPA031440: AB_2673883, HPA056104: AB_2683038" "unprognostic (1.25e-2)" "unprognostic (2.84e-1)" "unprognostic (4.35e-2)" "unprognostic (2.54e-2)" "unprognostic (1.01e-2)" "unprognostic (6.82e-2)" "unprognostic (2.39e-2)" "unprognostic (2.21e-1)" "unprognostic (3.20e-1)" "unprognostic (1.78e-1)" "unprognostic (1.22e-2)" "unprognostic (2.65e-1)" "unprognostic (3.22e-2)" "unprognostic (3.88e-2)" "unprognostic (5.88e-2)" "unprognostic (1.40e-1)" "unprognostic (2.84e-3)" 0.4 0.5 1.9 0.2 2.4 0.2 0.2 3.3 5.3 0.6 0.1 0.4 0.3 0.2 3.3 0.6 0.1 0.7 3.6 8.2 1.9 0.6 0.1 2.0 0.1 3.3 2.1 0.5 0.4 0.0 1.2 1.6 2.5 2.0 0.1 0.7 0.3 1.8 0.4 0.9 0.1 0.1 0.4 0.1 0.3 0.6 1.6 0.3 1.0 0.0 0.1 2.1 0.6 0.8 2.9 12.2 0.3 0.0 3.7 2.2 0.0 36.6 7.9 28.0 20.9 0.1 4.0 0.0 3.7 11.8 0.5 1.4 0.1 0.2 26.5 0.2 0.1 0.0 3.5 0.0 17.4 0.2 0.2 9.2 4.2 6.8 3.7 18.1 1.3 0.1 0.0 0.1 4.8 0.0 0.0 0.0 4.0 0.1 2.9 0.0 2.0 0.0 4.5 0.0 0.2 1.1 7.8 0.1 0.1 1.7 0.2 0.0 11.0 37.6 6.9 14.4 9.2 0.5 0.1 0.0 14.1 1.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.4 3.3 5.3 8.2 1.9 3.3 2.1 2.5 0.4 1.6 0.8 0.2 38.5 0.5 1.6 0.0 0.6 0.4 0.5 1.8 13.8 0.5 0.9 9.1 0.0 0.4 1.8 4.2 0.4 0.0 0.1 0.0 0.8 1.8 0.3 0.3 0.2 0.0 0.0 22.3 0.0 0.5 6.1 0.0 0.1 1.3 1.9 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.4 1.5 0.3 0.9 1.8 0.0 0.0 0.2 0.0 2.0 2.2 0.2 0.0 0.0 0.0 0.8 0.0 1.5 0.1 1.8 0.0 1.8 25.8 3.7 0.8 2.3 0.0 0.7 0.0 9.3 0.1 0.1 BIRC5 "API4, EPR-1, survivin" ENSG00000089685 "Baculoviral IAP repeat containing 5" O15392 17 78214186-78225636 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis, Transcription, Transcription regulation" "Protease inhibitor, Repressor, Thiol protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.9;lymphoid tissue: 41.0;testis: 19.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 74.7;Early spermatids: 94.1;Erythroid cells: 166.7;Extravillous trophoblasts: 162.0;Spermatocytes: 191.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 14.1" "Lineage enriched" "Detected in many" 6 "T-cells: 14.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002830, CAB004270" Enhanced Supported "Cytokinetic bridge" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Cytokinetic bridge" "CAB004270: AB_628302, HPA002830: AB_1857672" "unprognostic (8.04e-2)" "unprognostic (3.51e-2)" "unprognostic (4.48e-3)" "unprognostic (2.72e-3)" "unprognostic (3.37e-1)" "unprognostic (3.84e-2)" "prognostic unfavorable (5.28e-6)" "prognostic unfavorable (4.49e-4)" "unprognostic (3.56e-3)" "unprognostic (4.53e-3)" "unprognostic (2.87e-3)" "unprognostic (6.67e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.77e-2)" "unprognostic (4.70e-2)" "unprognostic (1.59e-1)" "unprognostic (1.16e-1)" 0.9 1.1 0.3 8.5 0.5 37.9 5.1 0.6 0.6 1.9 0.4 6.7 7.9 1.6 0.0 12.8 0.6 1.1 0.5 0.4 0.4 0.7 2.1 1.9 16.2 0.6 0.6 0.4 0.6 0.2 0.2 6.1 0.5 0.6 8.0 0.1 1.8 0.2 1.1 5.8 7.6 4.3 0.4 5.8 3.7 19.6 1.0 41.0 0.4 0.1 16.3 2.6 3.2 0.8 139.1 126.2 111.3 121.5 6.7 11.3 41.0 103.6 57.5 144.0 94.2 104.0 52.9 140.7 41.5 60.5 108.7 71.9 113.6 66.6 125.2 48.2 157.5 93.2 71.4 123.1 0.8 90.8 67.0 3.9 4.5 79.8 59.2 21.0 103.5 104.3 118.8 116.0 112.6 79.7 195.5 86.2 83.4 96.3 218.0 100.5 180.2 108.4 34.5 50.2 136.8 94.8 80.3 88.6 71.7 54.1 117.5 84.8 39.5 173.1 152.6 76.0 150.4 83.3 72.2 163.3 63.3 37.8 154.4 0.0 0.0 0.0 0.7 0.0 0.1 2.4 4.1 2.8 0.8 0.2 0.0 0.4 0.5 2.4 0.0 0.2 14.1 3.1 0.3 0.5 0.6 0.6 0.4 0.4 0.6 0.6 0.5 0.4 1.0 0.8 1.2 0.0 20.0 0.0 15.9 8.2 3.7 12.2 2.8 0.7 7.7 8.6 2.3 2.8 10.8 0.0 0.0 74.7 3.3 10.7 0.0 2.0 94.1 5.4 5.1 8.8 3.0 166.7 0.4 0.0 162.0 15.1 8.6 6.9 9.5 42.7 12.8 2.7 52.1 0.0 0.2 17.1 10.2 13.7 13.8 68.4 3.1 9.6 1.8 0.0 0.6 0.4 7.2 0.0 0.3 0.4 2.5 0.7 50.2 2.8 3.2 0.1 2.6 0.5 6.6 0.9 15.2 191.1 58.2 31.3 6.5 19.2 10.1 3.4 38.8 6.3 BORA "C13orf34, FLJ22624" ENSG00000136122 "BORA aurora kinase A activator" Q6PGQ7 13 72727749-72756198 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 13.5;Sertoli cells: 13.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA040866 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli fibrillar center" Cytosol "HPA040866: AB_10794868" "unprognostic (9.93e-2)" "unprognostic (7.18e-2)" "unprognostic (4.57e-2)" "unprognostic (7.09e-2)" "unprognostic (1.49e-1)" "unprognostic (1.47e-2)" "unprognostic (1.37e-4)" "unprognostic (2.65e-2)" "unprognostic (2.82e-3)" "unprognostic (6.18e-2)" "unprognostic (1.08e-2)" "unprognostic (2.11e-2)" "unprognostic (5.32e-12)" "unprognostic (7.04e-3)" "unprognostic (2.88e-1)" "unprognostic (9.93e-2)" "unprognostic (2.28e-2)" 1.6 1.3 1.2 4.3 1.2 6.0 2.4 1.4 1.7 1.6 1.9 4.2 4.3 1.3 1.5 3.5 1.4 1.3 1.0 1.2 1.3 1.8 1.7 1.8 7.6 1.6 1.3 1.2 1.7 0.5 1.9 2.3 1.5 1.8 5.0 3.5 1.9 1.0 1.1 4.2 3.5 1.7 1.1 4.2 3.2 4.0 1.4 8.1 1.9 0.9 6.8 2.2 2.2 1.5 32.5 8.5 19.6 14.7 2.4 2.4 11.6 9.8 8.6 17.9 18.1 20.6 17.2 23.8 6.4 6.4 10.3 15.0 17.1 11.5 22.1 20.9 12.3 28.7 11.4 15.8 1.7 54.2 17.1 1.9 2.6 8.9 15.1 5.0 14.6 22.8 12.7 10.7 14.6 9.8 20.8 21.8 10.8 36.8 6.0 16.4 12.3 10.6 6.5 10.0 6.9 7.0 12.0 12.8 10.2 15.0 6.4 24.6 4.8 5.8 9.7 8.3 16.3 6.9 7.0 14.8 16.3 24.8 13.9 1.3 1.1 0.5 1.9 1.9 2.3 1.6 1.8 2.0 1.9 1.9 1.6 2.5 0.1 1.8 1.2 1.4 1.9 1.1 1.2 1.2 1.4 1.7 1.2 1.3 1.6 1.3 1.5 1.1 1.4 1.5 1.6 3.2 2.8 3.6 5.4 0.6 1.3 2.2 3.4 1.7 1.4 1.3 0.3 1.5 2.1 1.8 2.1 7.5 3.9 3.1 0.0 1.9 12.6 2.2 2.3 1.4 0.0 13.5 4.3 2.6 11.5 1.7 3.6 2.4 1.3 5.1 1.8 0.4 4.6 8.4 3.1 2.7 0.0 2.8 1.5 2.7 0.9 2.8 0.0 3.7 3.5 1.1 4.1 2.5 7.3 1.7 2.2 1.2 5.2 1.2 3.2 0.8 2.7 2.3 13.1 1.6 1.5 11.8 4.3 3.4 1.1 2.9 4.1 1.5 5.8 1.4 BRCA1 "BRCC1, FANCS, PPP1R53, RNF53" ENSG00000012048 "BRCA1 DNA repair associated" P38398 17 43044295-43170245 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 42.5;Granulosa cells: 38.2;Spermatocytes: 105.8;Spermatogonia: 73.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 6.8;classical monocyte: 14.7;intermediate monocyte: 4.7;myeloid DC: 10.9;neutrophil: 11.3" "Group enriched" "Detected in all" 6 "dendritic cells: 10.9;granulocytes: 11.3;monocytes: 14.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB001946, HPA004840, HPA034966, HPA057371" Approved Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nuclear bodies" "CAB001946: , HPA004840: , HPA034966: AB_10795287, HPA057371: AB_2732611" "unprognostic (7.87e-3)" "unprognostic (6.97e-2)" "unprognostic (3.53e-3)" "unprognostic (2.39e-1)" "unprognostic (5.42e-2)" "unprognostic (7.07e-3)" "unprognostic (1.56e-3)" "unprognostic (4.14e-3)" "unprognostic (9.62e-3)" "unprognostic (2.47e-1)" "unprognostic (5.53e-3)" "unprognostic (1.28e-1)" "unprognostic (1.08e-4)" "unprognostic (1.08e-3)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (8.31e-2)" 3.1 1.8 4.2 7.5 7.2 13.0 3.6 4.7 5.2 2.7 2.7 6.8 3.2 3.1 2.2 4.0 3.7 1.9 3.0 3.6 4.1 2.0 5.6 3.2 10.3 5.6 5.0 2.8 2.8 5.9 2.8 3.8 6.0 2.4 7.4 8.2 3.2 1.6 4.2 6.0 5.1 3.9 3.7 3.9 3.6 13.0 5.5 14.5 7.8 3.7 11.2 2.8 2.4 10.8 44.1 69.1 37.8 30.1 6.0 13.4 36.6 50.6 21.5 41.9 39.3 42.3 33.4 100.8 9.1 19.0 49.0 49.5 51.9 28.3 69.5 46.9 38.0 48.1 54.0 37.1 1.3 86.0 39.9 3.8 4.5 63.1 20.0 10.6 22.3 46.6 73.7 42.2 39.7 30.0 72.0 27.8 20.5 29.1 18.7 49.0 79.8 40.8 15.4 42.1 25.8 27.4 38.8 12.5 19.4 25.5 33.9 39.6 13.8 37.2 29.6 49.0 53.2 20.1 51.2 75.5 29.6 49.6 39.4 6.8 14.7 2.2 1.5 4.7 1.5 1.2 1.5 1.2 10.9 2.1 1.3 1.5 11.3 1.5 2.0 1.7 0.5 17.5 4.2 7.2 4.7 5.2 3.6 4.1 5.6 5.0 6.0 3.7 5.5 10.8 5.0 0.0 2.8 9.4 5.8 2.9 4.5 1.9 1.2 10.3 4.4 5.2 10.1 5.7 3.5 1.8 22.9 12.8 8.1 6.2 0.0 3.0 11.9 14.0 6.3 4.7 0.0 42.5 3.0 1.1 18.2 7.4 6.1 4.2 8.2 38.2 5.3 18.3 10.1 11.8 4.4 7.5 0.0 3.9 2.8 8.0 2.5 6.4 0.0 4.7 4.9 2.4 5.2 3.0 18.7 1.7 2.4 1.5 16.6 2.3 1.1 1.0 10.0 22.8 6.6 13.7 5.5 105.8 73.5 8.2 2.3 4.0 4.7 9.7 12.7 3.4 BRD8 "p120, SMAP" ENSG00000112983 "Bromodomain containing 8" Q9H0E9 5 138139770-138178953 "Predicted intracellular proteins" "Growth regulation, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 120.8;Spermatocytes: 226.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001841 Supported Supported Nucleoplasm,Mitochondria NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Mitochondria "HPA001841: AB_1845438" "unprognostic (1.25e-1)" "unprognostic (1.20e-1)" "unprognostic (2.81e-3)" "unprognostic (2.31e-2)" "unprognostic (9.01e-2)" "unprognostic (3.56e-2)" "prognostic unfavorable (1.09e-6)" "unprognostic (1.73e-1)" "unprognostic (7.01e-2)" "unprognostic (6.06e-2)" "unprognostic (1.51e-2)" "unprognostic (4.87e-2)" "prognostic unfavorable (7.80e-4)" "unprognostic (4.29e-1)" "unprognostic (1.28e-1)" "unprognostic (2.22e-1)" "unprognostic (2.07e-2)" 21.8 21.5 23.4 15.4 24.2 22.4 25.1 27.4 28.5 30.1 21.5 30.5 15.5 28.4 41.3 23.5 26.6 16.4 19.5 22.0 23.4 25.0 25.4 19.5 20.6 21.5 21.1 32.7 30.6 26.2 46.6 24.9 22.2 27.3 24.8 38.7 25.1 23.9 27.8 23.6 23.3 25.1 20.8 27.6 24.9 83.1 22.7 38.0 34.3 25.1 22.1 24.3 24.8 29.6 28.7 36.8 63.1 101.8 45.0 42.0 57.0 43.4 47.9 61.6 64.4 55.4 62.6 28.6 42.2 40.3 62.9 32.9 67.4 41.5 65.9 50.3 50.1 38.5 93.6 38.0 25.0 23.6 39.2 31.4 27.2 48.7 44.1 49.3 39.7 52.2 35.2 35.8 41.3 31.8 48.4 37.6 28.6 32.9 18.8 46.4 52.2 35.1 41.4 41.3 55.7 27.9 51.9 22.4 40.1 85.0 38.5 43.2 25.0 30.2 34.7 21.2 38.1 31.5 37.9 39.1 23.1 34.7 28.5 16.2 10.8 14.1 14.6 8.0 15.8 10.7 12.7 13.2 12.0 11.0 15.9 16.0 20.2 23.8 8.8 8.4 13.0 9.8 23.4 24.2 27.4 28.5 22.0 23.4 21.5 21.1 22.2 20.8 22.7 29.6 21.0 25.6 38.3 28.1 17.8 6.9 10.6 16.4 31.9 33.7 19.8 20.3 44.8 14.3 27.0 27.6 37.5 27.7 19.0 17.0 19.6 19.5 120.8 30.1 51.1 24.3 31.2 26.5 26.2 12.4 13.2 32.5 20.9 29.7 24.0 43.2 13.6 17.2 11.9 30.3 23.7 23.3 14.2 14.8 9.8 43.9 31.4 14.3 24.9 12.2 31.3 27.1 19.6 27.6 30.8 16.0 16.8 24.0 21.8 18.1 15.4 22.4 29.0 34.9 26.3 23.2 31.7 226.9 65.0 23.2 7.0 25.3 19.1 41.9 18.6 10.1 BRI3BP "BNAS1, HCCR-2, HCCRBP-3, KG19" ENSG00000184992 "BRI3 binding protein" Q8WY22 12 124993645-125031231 "Predicted membrane proteins, Transporters" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 20.8" "Cell type enhanced" "Detected in many" "Late spermatids: 174.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 13.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Daudi: 114.9;U-698: 161.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014957 Approved Approved Nucleoplasm,Mitochondria NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 45: Intestine - Brush border" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria" "HPA014957: AB_1845447" "unprognostic (1.62e-2)" "unprognostic (6.82e-2)" "unprognostic (1.53e-2)" "unprognostic (9.95e-2)" "unprognostic (4.66e-2)" "unprognostic (1.20e-2)" "prognostic unfavorable (6.87e-4)" "unprognostic (7.65e-3)" "unprognostic (2.84e-2)" "unprognostic (3.47e-3)" "unprognostic (7.40e-2)" "unprognostic (4.82e-2)" "unprognostic (2.72e-3)" "unprognostic (1.44e-3)" "unprognostic (2.20e-1)" "unprognostic (9.20e-2)" "unprognostic (1.55e-1)" 3.3 2.0 9.2 8.9 10.7 5.5 5.5 8.2 10.7 3.0 7.1 15.5 20.8 2.1 2.2 6.8 4.1 4.8 2.5 9.2 7.9 6.9 4.8 2.8 13.8 9.6 9.7 1.5 5.1 9.1 2.1 2.1 10.2 2.9 15.3 10.0 2.5 2.2 1.7 5.5 18.8 2.6 9.1 5.9 8.2 1.8 9.1 7.0 4.4 2.1 16.2 2.5 2.6 9.4 34.1 43.8 13.8 12.5 10.9 5.6 24.1 22.2 4.6 13.7 7.1 36.1 22.3 114.9 27.8 5.0 8.9 38.7 30.7 17.3 10.9 26.9 25.5 58.4 16.9 24.8 2.2 86.8 72.2 2.5 9.9 15.0 7.1 5.3 5.1 41.0 23.5 8.0 12.0 31.3 45.1 33.3 9.9 29.9 17.3 30.2 23.0 30.7 17.3 46.8 19.0 13.2 27.6 26.9 9.2 4.6 48.8 60.8 5.9 13.0 16.2 12.5 23.4 26.9 49.7 161.8 11.9 28.7 29.1 4.2 2.2 13.1 0.8 1.6 0.8 1.4 0.6 0.7 1.7 1.5 0.5 0.7 2.2 0.9 1.2 4.2 0.7 0.6 9.2 10.7 8.2 10.7 9.2 7.9 9.6 9.7 10.2 9.1 9.1 9.4 3.4 9.6 10.4 13.4 23.6 12.2 9.1 8.2 5.2 37.1 14.9 6.3 7.2 31.5 9.2 9.2 14.6 15.4 24.3 65.5 3.9 9.1 25.6 16.1 7.2 5.1 7.8 21.5 32.6 10.4 24.0 7.1 32.1 18.0 18.4 7.2 4.2 27.4 19.8 25.2 43.8 42.8 8.2 31.5 26.1 174.4 1.2 23.6 10.6 11.2 28.8 12.1 9.2 11.1 23.4 17.1 43.3 4.1 39.5 9.6 60.2 12.7 15.0 27.9 0.0 9.2 6.9 1.1 11.5 20.7 18.3 5.2 11.5 6.8 72.6 9.7 BRIP1 "BACH1, FANCJ, OF" ENSG00000136492 "BRCA1 interacting protein C-terminal helicase 1" Q9BX63 17 61679139-61863528 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Helicase, Hydrolase" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 7.2;lymphoid tissue: 5.9;testis: 7.0" "Group enriched" "Detected in many" 12 "Early spermatids: 186.2;Late spermatids: 194.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 88.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005474 Approved Supported "Nucleoplasm,Nuclear membrane" NA Yes "Cluster 26: Non-specific - Mitochondria" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Nuclear membrane" "HPA005474: AB_2667333" "unprognostic (1.88e-1)" "unprognostic (1.55e-2)" "prognostic favorable (3.45e-5)" "unprognostic (6.85e-4)" "unprognostic (3.09e-1)" "prognostic favorable (3.62e-4)" "unprognostic (2.60e-3)" "unprognostic (5.60e-2)" "unprognostic (5.66e-3)" "unprognostic (6.71e-2)" "unprognostic (1.50e-3)" "unprognostic (2.75e-2)" "unprognostic (3.41e-12)" "unprognostic (1.19e-2)" "unprognostic (2.25e-1)" "unprognostic (3.96e-2)" "unprognostic (3.62e-3)" 0.3 0.3 0.8 1.7 0.6 7.2 0.9 1.3 0.9 0.4 0.0 1.7 2.0 0.8 0.4 1.5 0.3 0.6 0.1 0.5 0.2 0.3 1.6 0.4 2.8 0.3 0.0 1.1 0.3 0.1 0.0 0.8 0.4 0.4 1.9 0.5 0.4 0.2 0.1 2.0 1.9 0.9 0.0 0.7 0.9 7.0 0.2 5.9 0.3 0.1 3.3 0.7 0.6 0.8 26.6 9.4 25.0 14.1 0.9 2.1 5.5 23.6 13.3 24.6 31.8 9.5 8.0 14.9 5.2 4.9 7.7 9.2 12.8 4.5 33.3 3.8 15.8 15.5 14.4 10.5 0.2 20.3 8.8 0.6 0.4 20.2 5.1 3.4 5.0 14.8 11.6 10.5 14.4 88.9 32.5 6.7 5.3 5.9 7.3 19.7 50.1 7.1 3.0 12.8 10.0 24.2 9.4 3.0 3.3 9.1 8.3 7.3 4.5 36.9 26.5 13.5 26.6 6.3 13.3 16.6 7.3 9.3 8.8 1.0 0.1 0.4 0.1 0.0 0.1 0.5 0.3 0.1 0.1 0.6 0.4 0.2 0.3 0.1 0.1 0.1 1.0 0.1 0.8 0.6 1.3 0.9 0.5 0.2 0.3 0.0 0.4 0.0 0.2 0.8 0.2 0.0 0.5 1.0 1.6 2.3 1.3 0.8 0.6 0.3 1.1 1.8 0.6 0.0 4.0 0.0 0.0 2.0 2.0 1.8 0.0 0.3 186.2 0.7 1.7 0.8 0.0 7.4 4.6 0.2 3.0 2.0 2.0 1.6 0.0 15.5 0.4 3.4 1.7 0.0 3.3 1.8 0.0 0.8 1.1 194.1 1.2 1.0 3.6 2.8 0.6 0.2 1.0 1.5 1.0 0.8 0.1 1.2 4.8 0.4 1.4 0.2 0.8 0.2 0.0 2.5 1.8 12.1 6.0 2.9 0.4 0.3 2.3 2.1 4.7 0.7 BTBD10 "GMRP-1, GMRP1, MGC13007" ENSG00000148925 "BTB domain containing 10" Q9BSF8 11 13388008-13463297 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 116.5;Spermatocytes: 121.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046777 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nucleoli fibrillar center" "HPA046777: AB_2679801" "unprognostic (2.38e-1)" "unprognostic (4.25e-1)" "unprognostic (1.75e-1)" "unprognostic (9.76e-2)" "unprognostic (1.59e-1)" "unprognostic (1.84e-2)" "prognostic unfavorable (1.37e-4)" "unprognostic (1.07e-1)" "unprognostic (2.52e-1)" "unprognostic (3.00e-1)" "unprognostic (1.29e-3)" "unprognostic (1.15e-2)" "unprognostic (1.43e-1)" "unprognostic (1.32e-1)" "unprognostic (2.02e-1)" "unprognostic (6.98e-2)" "unprognostic (1.27e-1)" 13.8 12.2 19.8 13.6 30.9 13.4 13.3 18.8 27.9 15.0 3.2 18.1 13.1 16.5 12.0 28.6 11.8 15.2 17.7 25.9 18.6 11.4 9.8 13.0 15.7 12.0 15.7 14.1 8.7 13.2 14.1 17.4 16.2 15.0 20.3 18.8 10.8 17.4 14.6 13.1 11.7 21.1 10.0 12.6 17.7 38.3 14.5 18.5 13.6 18.4 17.4 27.1 17.8 22.2 55.9 40.2 34.3 23.2 30.4 29.5 43.5 57.5 33.3 43.5 39.4 37.7 64.0 38.1 27.1 42.2 43.9 44.0 26.3 61.4 50.8 38.7 27.1 20.7 13.9 22.5 46.9 27.6 45.4 25.3 68.0 25.2 57.3 33.0 89.1 26.8 11.8 38.2 46.0 33.7 28.3 15.2 14.9 50.0 34.9 24.8 29.4 23.8 69.7 44.3 14.8 20.9 34.4 27.5 20.5 38.9 19.7 14.7 81.7 44.7 37.2 43.4 33.6 14.2 52.6 25.5 30.6 23.6 38.9 41.1 24.8 38.2 18.1 39.7 21.7 18.4 17.1 20.1 29.2 17.2 19.1 19.3 64.9 25.7 50.5 12.7 23.6 18.3 19.8 30.9 18.8 27.9 25.9 18.6 12.0 15.7 16.2 10.0 14.5 22.2 20.5 16.0 7.0 35.9 16.9 28.2 40.7 27.0 15.9 13.9 9.6 8.6 14.0 12.8 19.7 5.5 4.2 24.3 18.1 15.7 5.9 31.8 95.7 14.3 12.5 22.6 16.3 9.0 116.5 25.2 54.3 15.3 27.5 19.1 22.8 11.1 11.7 5.9 22.9 8.4 74.2 14.2 28.5 16.4 13.0 26.3 9.9 13.0 17.8 38.4 22.2 9.9 18.6 61.9 62.4 50.2 14.2 18.4 12.0 30.1 8.7 10.5 19.9 14.1 6.6 13.4 20.6 121.3 59.7 27.8 35.8 62.1 17.8 9.2 13.3 64.6 BTF3 "BTF3a, BTF3b, NACB" ENSG00000145741 "Basic transcription factor 3" P20290 5 73498408-73505635 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013007, HPA056420" Approved Supported Cytosol NA Yes 180000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Cytosol "CAB013007: , HPA056420: AB_2683125" "unprognostic (3.48e-3)" "unprognostic (2.11e-1)" "unprognostic (2.87e-3)" "unprognostic (1.86e-1)" "unprognostic (6.25e-2)" "unprognostic (1.41e-1)" "unprognostic (1.90e-3)" "unprognostic (1.78e-2)" "unprognostic (8.20e-3)" "unprognostic (5.18e-2)" "unprognostic (8.47e-2)" "unprognostic (1.01e-1)" "unprognostic (2.36e-2)" "unprognostic (1.06e-1)" "unprognostic (2.87e-1)" "unprognostic (1.26e-2)" "unprognostic (2.16e-1)" 633.3 440.1 241.0 373.7 251.2 861.1 763.0 250.7 307.9 658.2 234.9 593.6 460.9 547.0 422.0 735.8 584.3 376.6 477.8 230.9 261.7 469.8 522.5 416.4 644.4 256.5 247.8 1180.8 609.6 401.9 288.1 429.5 259.1 441.1 540.1 183.9 509.2 390.8 880.0 782.4 446.7 459.1 256.5 393.7 534.8 181.7 242.0 629.3 440.1 600.1 758.9 624.2 626.6 272.0 1148.3 747.2 798.7 1145.9 779.6 1301.4 1246.4 781.1 1084.9 1327.8 1267.4 972.1 1267.3 1719.2 1203.2 816.0 963.9 787.9 1176.6 2011.7 1517.2 716.2 1502.5 976.3 652.7 1280.2 1132.7 934.0 754.5 1139.7 1597.0 857.6 1572.3 1512.0 1227.4 975.3 924.1 1087.8 1134.7 1037.8 1410.0 1735.0 1017.4 423.0 742.0 1061.5 944.4 2147.0 1414.6 1126.0 930.6 1239.4 767.0 861.7 1650.4 744.4 1108.4 1884.6 894.7 569.6 780.5 690.2 2142.1 1020.7 1114.3 1607.2 757.0 1405.3 862.8 261.1 883.1 221.9 535.6 684.0 907.0 957.3 906.7 754.3 1140.2 788.4 986.3 892.7 116.0 878.6 556.1 637.6 1146.0 2128.9 241.0 251.2 250.7 307.9 230.9 261.7 256.5 247.8 259.1 256.5 242.0 272.0 753.2 246.8 324.7 17.0 889.7 1962.5 2039.6 2425.9 1664.7 138.9 1675.6 2355.4 357.8 566.2 908.0 323.7 43.8 1370.6 740.7 648.3 909.8 971.1 718.0 502.1 809.7 864.3 592.8 968.4 25.2 1219.7 2062.4 753.8 465.3 646.9 417.7 935.1 742.8 439.4 1066.3 85.8 29.3 1169.4 787.3 968.7 1357.2 464.2 1248.3 803.3 791.5 29.0 1487.9 376.5 726.1 20.6 49.6 1221.7 998.2 846.3 540.1 1626.5 1308.9 1229.5 432.9 137.6 644.2 1023.8 1051.0 333.7 238.2 1582.0 1953.2 1712.1 868.7 1029.7 1337.1 2269.9 BTG3 "ANA, ANA/BTG3, APRO4, tob55" ENSG00000154640 "BTG anti-proliferation factor 3" Q14201 21 17593653-17612945 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 526.3;Syncytiotrophoblasts: 1692.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 31.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018400 Approved NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 68: Epididymis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA018400: AB_1845487" "unprognostic (2.39e-1)" "unprognostic (1.15e-2)" "unprognostic (6.39e-2)" "unprognostic (2.27e-1)" "unprognostic (2.34e-1)" "unprognostic (2.98e-3)" "prognostic unfavorable (1.16e-4)" "unprognostic (4.50e-3)" "unprognostic (1.75e-1)" "unprognostic (1.43e-2)" "unprognostic (2.67e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (7.37e-4)" "unprognostic (2.42e-2)" "unprognostic (3.08e-1)" "unprognostic (9.92e-2)" "unprognostic (2.40e-1)" 30.8 27.9 13.1 14.0 14.6 55.9 24.2 13.3 16.1 32.0 14.0 28.8 16.5 48.2 110.3 25.4 51.5 22.8 28.8 14.4 16.2 23.5 12.9 44.7 13.9 14.8 13.4 28.4 21.0 35.3 43.7 61.1 15.0 25.2 26.9 5.1 27.2 20.5 4.9 42.5 16.4 28.4 14.7 15.1 21.2 47.5 15.5 27.4 27.2 5.3 16.4 39.3 37.7 17.8 70.5 14.4 84.9 6.8 28.4 50.9 62.6 96.0 109.8 83.5 84.9 33.0 29.3 31.5 44.7 34.8 108.7 17.1 42.5 63.3 91.9 99.6 60.6 23.5 30.9 31.5 59.4 26.6 44.3 44.4 88.2 70.8 67.7 47.7 42.0 30.7 22.9 113.6 78.3 0.0 51.2 4.0 44.4 9.7 4.2 16.6 110.5 23.1 55.2 31.3 43.2 34.9 71.9 36.6 86.7 96.0 1.2 28.6 27.7 84.0 89.1 65.6 96.9 74.1 64.6 29.5 84.4 0.2 102.2 1.0 2.3 4.0 8.1 1.7 9.4 7.4 13.6 13.0 1.9 6.3 6.6 9.1 0.2 6.2 1.9 8.8 31.7 5.5 13.1 14.6 13.3 16.1 14.4 16.2 14.8 13.4 15.0 14.7 15.5 17.8 65.2 205.1 156.5 0.7 44.7 360.1 526.3 309.9 178.7 1.1 64.8 55.0 9.3 34.3 195.5 58.8 0.0 436.5 61.6 25.3 39.2 56.9 8.6 197.0 97.1 51.0 108.3 99.1 2.2 39.3 88.6 132.5 17.9 147.3 65.4 13.5 32.2 5.5 55.6 23.5 3.1 47.9 69.2 16.5 140.4 24.8 70.2 54.5 85.4 16.9 33.5 19.5 12.3 20.1 14.6 52.9 22.7 46.6 75.1 463.0 2.6 2.1 104.3 1.0 92.1 95.5 99.1 300.0 267.2 92.7 294.4 1692.7 99.2 47.5 48.6 470.3 BUB1 "BUB1A, BUB1L, hBUB1" ENSG00000169679 "BUB1 mitotic checkpoint serine/threonine kinase" O43683 2 110637528-110678063 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Host-virus interaction, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 11.9;lymphoid tissue: 27.5;testis: 30.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 24.8;Granulosa cells: 66.1;Plasma cells: 35.2;Spermatocytes: 85.6;Spermatogonia: 20.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 221.5" "Region enhanced" "Detected in single" "white matter: 1.7" "Not detected" "Not detected" HPA006123 Supported Nucleoplasm,Cytosol NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 36: HEL - Hemostasis" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA006123: AB_1845498" "unprognostic (7.74e-2)" "unprognostic (3.45e-2)" "unprognostic (9.72e-3)" "prognostic unfavorable (3.65e-4)" "unprognostic (1.61e-1)" "unprognostic (5.62e-3)" "prognostic unfavorable (1.03e-5)" "prognostic unfavorable (3.94e-4)" "unprognostic (1.26e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.37e-5)" "unprognostic (1.76e-1)" "unprognostic (0.00e+0)" "unprognostic (2.45e-2)" "unprognostic (3.64e-1)" "unprognostic (5.01e-2)" "unprognostic (1.28e-1)" 0.5 0.4 0.1 8.4 0.3 11.9 1.2 0.1 0.1 0.9 0.0 4.3 4.0 1.0 3.5 4.7 0.5 0.9 0.6 0.1 0.1 0.3 0.6 1.2 15.9 0.1 0.6 0.4 0.2 0.7 0.0 3.2 0.3 0.3 5.7 0.1 0.9 0.1 0.1 2.7 3.5 2.2 0.0 5.6 1.9 30.3 0.4 27.5 0.4 0.2 17.0 2.4 1.6 0.3 96.0 29.4 68.5 46.8 3.8 5.3 38.8 50.9 32.9 85.6 62.3 58.3 55.0 64.7 30.9 30.1 80.1 43.2 93.9 35.0 105.7 51.4 45.6 221.5 26.2 50.6 0.8 63.5 57.0 1.7 2.8 65.2 33.1 12.7 49.8 73.2 96.8 126.5 76.8 33.7 126.3 39.0 71.2 39.4 55.3 69.3 64.2 102.7 18.3 27.0 48.3 21.4 34.2 31.4 27.2 44.1 24.0 60.6 19.1 39.7 57.5 28.8 69.0 67.3 65.5 75.4 24.2 48.6 69.8 1.1 0.0 0.2 0.2 0.0 0.3 0.5 0.9 0.5 0.1 0.5 0.6 0.4 0.0 0.5 0.0 0.9 1.5 0.3 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.6 0.3 0.0 0.4 0.3 0.2 0.0 1.5 0.0 5.5 0.5 0.5 2.0 0.6 0.0 0.9 0.8 1.1 0.0 1.6 0.0 0.0 5.8 2.5 2.4 0.0 0.3 13.5 4.5 1.5 1.1 0.0 24.8 0.2 0.0 9.8 2.2 2.0 2.2 0.0 66.1 1.8 0.3 8.1 0.0 0.2 3.1 4.1 1.6 1.4 7.5 0.3 2.0 0.0 0.0 0.6 0.0 0.0 0.5 1.0 0.1 0.0 0.4 35.2 0.5 0.3 0.1 1.8 0.0 6.6 0.2 3.7 85.6 20.0 4.0 0.4 0.7 2.9 0.5 5.9 0.9 BUB1B "Bub1A, BUBR1, MAD3L, SSK1" ENSG00000156970 "BUB1 mitotic checkpoint serine/threonine kinase B" O60566 15 40161023-40221123 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.8;lymphoid tissue: 35.7;testis: 22.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 23.5;Spermatocytes: 79.2;Spermatogonia: 26.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA008419 Supported Cytosol Yes Yes "Cluster 24: B-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA008419: AB_1078308" "unprognostic (4.40e-2)" "unprognostic (2.23e-1)" "unprognostic (4.65e-2)" "unprognostic (2.44e-3)" "unprognostic (9.66e-2)" "unprognostic (3.52e-2)" "prognostic unfavorable (7.43e-6)" "prognostic unfavorable (3.56e-4)" "unprognostic (3.69e-3)" "unprognostic (2.32e-1)" "prognostic unfavorable (1.79e-4)" "unprognostic (1.76e-2)" "unprognostic (0.00e+0)" "unprognostic (3.75e-2)" "unprognostic (4.66e-2)" "unprognostic (2.20e-1)" "unprognostic (3.94e-2)" 0.4 0.5 0.1 6.7 0.1 17.8 1.6 0.3 0.2 1.0 7.7 4.6 4.7 1.2 0.3 5.2 0.6 0.6 0.3 0.3 0.1 0.3 0.4 1.0 12.6 0.0 0.1 0.2 0.2 0.2 0.1 3.4 0.1 0.4 6.0 0.1 0.9 0.2 0.0 3.5 4.1 2.1 0.0 3.1 2.4 22.2 0.2 35.7 0.5 0.0 15.0 1.5 1.7 0.0 66.5 32.8 103.0 41.5 2.5 7.1 33.2 60.9 34.2 64.6 55.7 48.1 25.0 59.7 33.5 22.7 59.0 72.6 98.8 33.2 70.5 51.8 52.1 86.4 83.6 45.5 0.2 79.0 45.7 1.6 2.0 39.2 37.1 12.9 47.7 66.5 76.4 61.7 65.6 22.5 62.5 48.9 70.2 55.6 36.8 66.5 83.7 45.2 19.9 33.1 67.1 40.8 38.0 35.9 13.3 45.1 41.9 40.9 27.6 49.3 51.8 49.2 55.5 32.1 58.2 95.6 26.3 87.8 65.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.1 0.2 1.1 0.0 0.1 0.0 0.1 0.0 0.8 0.0 0.1 0.1 0.1 0.3 0.2 0.3 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.1 3.2 1.1 0.3 1.8 0.8 0.3 1.0 1.8 0.7 0.9 2.0 0.8 0.0 1.9 0.0 0.0 5.4 0.6 1.8 0.0 0.4 3.0 0.9 1.4 1.0 0.0 23.5 0.7 0.0 6.7 2.4 5.6 2.1 0.0 12.9 1.1 0.3 5.2 0.0 0.7 2.5 0.0 1.9 1.7 3.3 1.5 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 1.5 0.4 12.6 0.3 0.3 0.1 0.2 0.2 6.6 0.2 1.7 79.2 26.8 6.9 0.3 0.8 1.8 0.8 5.4 0.6 BUB3 BUB3L ENSG00000154473 "BUB3 mitotic checkpoint protein" O43684 10 123154402-123170467 "Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003601, CAB037075" Supported Supported Nucleoplasm NA Yes 39000 "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB037075: AB_1078310, HPA003601: AB_1078309" "unprognostic (7.82e-2)" "prognostic favorable (2.04e-4)" "unprognostic (9.07e-2)" "unprognostic (1.83e-1)" "unprognostic (7.93e-2)" "unprognostic (8.60e-2)" "prognostic unfavorable (4.45e-5)" "unprognostic (6.04e-3)" "unprognostic (9.41e-2)" "unprognostic (6.30e-3)" "unprognostic (2.69e-2)" "unprognostic (1.37e-2)" "prognostic unfavorable (3.81e-7)" "unprognostic (8.80e-2)" "unprognostic (7.64e-2)" "unprognostic (1.51e-1)" "unprognostic (7.71e-2)" 36.6 49.8 27.3 63.3 34.5 102.9 41.1 35.0 35.0 36.0 30.7 49.0 42.2 35.7 35.2 56.6 37.6 35.8 28.0 31.9 36.4 32.6 34.9 33.5 99.9 34.1 50.6 42.9 30.1 32.6 36.0 38.2 39.6 30.6 49.1 25.5 39.5 28.8 36.9 44.1 47.7 36.4 35.7 52.9 38.4 58.5 33.0 100.6 37.4 33.5 87.2 49.5 40.4 48.6 309.8 302.5 190.4 211.5 105.4 100.3 166.2 316.2 329.5 340.3 268.8 266.3 203.2 275.9 116.3 145.2 163.6 195.9 285.1 343.0 349.9 228.8 294.2 173.0 355.1 291.8 110.1 338.1 206.8 86.5 132.9 307.9 382.4 182.1 232.7 228.9 216.1 266.7 308.4 264.1 281.8 206.9 117.6 159.0 293.0 378.6 96.2 175.7 156.3 333.1 141.4 143.1 179.2 116.6 151.9 77.5 135.0 173.4 188.5 262.4 163.9 167.6 473.8 143.0 220.6 433.9 143.0 333.2 113.2 200.3 113.2 165.7 246.0 122.2 224.1 216.7 223.0 251.0 119.1 209.7 237.9 249.3 56.1 241.6 112.3 127.6 366.9 294.0 27.3 34.5 35.0 35.0 31.9 36.4 34.1 50.6 39.6 35.7 33.0 48.6 55.8 25.6 36.5 15.3 99.7 130.5 65.5 154.6 73.4 30.8 53.4 48.8 39.2 44.3 66.9 38.6 10.4 108.1 119.0 37.1 70.5 68.8 160.8 26.1 41.4 62.1 40.7 93.6 14.4 58.9 136.5 62.6 34.7 28.1 50.7 56.3 45.0 43.0 80.7 10.1 12.9 57.3 118.0 58.1 68.6 159.3 45.1 53.1 96.0 16.9 140.4 55.7 97.9 21.6 35.9 64.1 40.2 46.3 107.1 64.7 44.5 78.4 51.2 25.1 105.2 42.2 70.6 199.8 145.4 86.3 133.3 65.0 150.3 84.1 67.8 62.9 C11orf68 "BLES03, P5326" ENSG00000175573 "Chromosome 11 open reading frame 68" Q9H3H3 11 65916810-65919062 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045938 Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim" No Yes "Cluster 10: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA045938: AB_10961633" "unprognostic (3.18e-1)" "unprognostic (3.35e-2)" "unprognostic (2.38e-2)" "unprognostic (4.48e-2)" "unprognostic (1.23e-1)" "unprognostic (9.25e-2)" "unprognostic (1.15e-2)" "unprognostic (9.88e-2)" "unprognostic (5.98e-2)" "unprognostic (9.88e-2)" "unprognostic (2.73e-1)" "unprognostic (1.50e-3)" "prognostic favorable (5.02e-6)" "unprognostic (2.16e-1)" "unprognostic (3.55e-1)" "unprognostic (3.07e-2)" "unprognostic (1.18e-1)" 36.0 29.3 68.1 14.9 70.3 10.1 33.5 74.7 82.3 50.4 59.4 50.1 17.2 56.1 39.0 29.7 40.5 20.7 50.7 71.0 65.1 31.2 28.0 31.9 24.8 69.0 67.0 43.4 27.2 25.6 24.0 23.4 67.6 42.6 15.7 12.5 30.9 31.7 81.1 32.8 31.0 27.0 66.3 41.6 32.8 53.9 67.9 29.1 32.6 51.4 21.3 45.9 39.5 71.4 76.4 33.6 20.4 22.2 70.0 67.3 17.6 59.7 90.2 74.3 45.2 12.6 83.9 15.6 40.6 89.5 118.6 24.0 15.9 36.6 39.8 24.2 16.1 18.5 23.4 33.2 55.7 14.9 23.7 62.9 53.8 53.9 58.9 76.6 56.1 26.1 25.1 37.7 136.2 34.5 19.7 35.9 20.5 16.5 165.8 28.8 23.1 44.4 39.6 14.5 13.9 21.6 23.1 30.1 59.8 21.0 39.0 14.0 61.4 118.0 57.9 162.1 30.9 25.3 11.9 13.1 69.8 11.1 94.1 6.8 2.5 3.7 5.3 3.9 3.8 3.0 3.4 4.4 2.0 5.3 5.2 5.2 9.1 3.8 2.1 2.7 4.2 2.2 68.1 70.3 74.7 82.3 71.0 65.1 69.0 67.0 67.6 66.3 67.9 71.4 17.8 16.0 5.1 6.5 7.3 15.3 32.9 4.2 6.8 11.4 14.7 22.5 16.6 14.3 2.3 16.5 10.4 16.4 14.5 10.8 7.9 14.5 7.9 8.1 17.8 13.8 4.8 2.1 7.9 11.7 16.5 18.5 7.1 11.8 3.8 12.9 18.2 10.5 14.2 16.8 7.5 13.1 4.1 13.9 7.5 24.5 21.5 8.7 10.6 7.5 14.1 26.7 22.6 4.5 8.6 19.3 3.4 35.3 3.6 23.2 11.8 5.4 1.9 9.9 19.7 13.5 16.4 15.0 17.1 6.2 12.8 21.9 8.3 23.3 9.2 31.3 C12orf65 "FLJ38663, SPG55" ENSG00000130921 "Chromosome 12 open reading frame 65" Q9H3J6 12 123233385-123258079 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" RNA-binding "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 60.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057595 Approved Approved Nucleoplasm,Mitochondria,Cytosol No Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 63: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Cytosol" Mitochondria "HPA057595: " "unprognostic (9.07e-3)" "unprognostic (1.51e-2)" "unprognostic (5.30e-2)" "unprognostic (8.19e-3)" "unprognostic (1.23e-1)" "unprognostic (2.58e-1)" "prognostic unfavorable (4.29e-9)" "unprognostic (9.33e-3)" "unprognostic (2.39e-1)" "unprognostic (2.50e-2)" "unprognostic (6.33e-3)" "unprognostic (1.20e-2)" "unprognostic (2.01e-2)" "unprognostic (3.89e-2)" "unprognostic (3.19e-2)" "unprognostic (9.83e-3)" "prognostic favorable (7.82e-5)" 7.3 12.6 16.2 10.2 16.1 9.0 8.0 23.0 19.6 13.0 13.5 10.9 11.4 12.1 13.8 9.5 11.4 8.2 15.0 16.0 13.2 12.6 14.5 8.9 18.2 12.6 12.3 17.2 8.5 10.2 19.7 7.3 14.9 13.7 8.2 15.7 16.2 9.0 13.0 13.8 11.3 7.0 8.8 12.8 10.6 16.7 14.8 60.0 12.3 12.5 13.4 10.3 11.0 18.3 28.4 20.5 20.8 39.1 12.0 11.1 13.7 22.3 16.5 25.1 18.0 21.8 15.8 36.1 20.3 8.4 23.5 20.4 25.7 12.5 25.0 29.2 22.5 44.0 20.7 18.6 26.1 20.4 19.7 14.2 33.2 18.9 35.1 37.0 17.0 53.6 45.6 13.4 16.7 12.3 46.2 39.3 13.7 25.6 31.7 35.7 25.9 33.5 22.8 13.0 40.7 18.2 24.0 8.8 23.4 16.5 18.3 24.7 14.8 23.1 27.3 23.3 24.4 22.7 28.3 32.6 17.1 26.2 28.1 85.3 12.9 50.6 53.9 14.9 67.6 83.9 72.3 71.9 21.7 73.5 96.6 78.2 11.8 63.3 16.3 36.6 73.1 33.5 16.2 16.1 23.0 19.6 16.0 13.2 12.6 12.3 14.9 8.8 14.8 18.3 46.0 41.7 47.7 9.8 54.3 45.4 36.7 29.4 59.2 34.5 23.3 50.0 52.7 14.3 18.0 25.8 14.6 41.1 56.2 16.4 60.7 20.7 22.9 12.2 24.2 27.9 9.6 37.0 13.7 10.8 22.8 41.3 23.0 11.2 15.2 24.1 18.5 33.5 14.3 45.4 15.9 20.7 28.5 9.2 24.2 6.2 37.9 19.7 24.9 7.5 26.3 35.7 44.3 14.6 10.4 13.6 17.4 42.2 42.2 22.8 19.9 39.3 14.8 36.6 13.1 42.7 33.1 115.2 59.7 40.6 36.1 10.8 63.0 43.3 20.8 8.0 C21orf58 ENSG00000160298 "Chromosome 21 open reading frame 58" P58505 21 46300181-46323875 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 26.4;pituitary gland: 20.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 141.9;Enteroendocrine cells: 69.4;Erythroid cells: 80.2;Respiratory ciliated cells: 164.1;Spermatocytes: 80.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "basophil: 4.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 4.4" "Cell line enhanced" "Detected in many" "REH: 62.0" "Not detected" "Not detected" "HPA035110, HPA035111" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 14: REH - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Nuclear bodies" "HPA035110: AB_10603683, HPA035111: AB_2674468" "unprognostic (2.19e-1)" "unprognostic (6.74e-3)" "unprognostic (2.51e-1)" "unprognostic (6.31e-3)" "unprognostic (1.08e-2)" "prognostic favorable (7.00e-4)" "unprognostic (4.74e-3)" "unprognostic (6.14e-2)" "prognostic unfavorable (7.48e-4)" "unprognostic (1.38e-1)" "prognostic favorable (4.20e-4)" "unprognostic (1.27e-1)" "unprognostic (1.01e-10)" "unprognostic (1.04e-1)" "unprognostic (1.70e-1)" "unprognostic (2.51e-1)" "unprognostic (6.07e-2)" 1.5 1.7 1.9 3.6 2.4 13.1 2.0 2.6 2.3 3.5 3.0 3.2 4.7 2.0 0.7 3.9 26.4 1.0 1.3 1.8 1.9 1.5 1.7 4.8 6.3 2.8 4.6 2.6 2.5 1.2 20.7 2.0 2.0 2.9 2.6 2.5 2.3 1.5 1.7 5.3 4.4 1.3 1.8 3.4 3.5 7.1 2.5 12.8 2.1 0.7 3.8 2.1 2.7 3.2 26.0 11.6 30.2 19.0 2.9 4.0 16.7 15.7 5.7 10.8 10.5 5.4 18.6 18.6 3.8 4.4 12.5 20.3 8.1 6.7 3.2 19.9 17.8 29.9 35.2 3.1 0.7 8.6 16.6 1.7 1.4 7.7 1.9 4.0 6.8 45.4 17.4 48.1 8.9 10.6 42.7 11.6 13.0 7.2 5.7 62.0 13.6 16.6 3.4 4.8 24.7 15.4 11.7 8.3 3.7 6.4 20.5 17.1 4.7 6.6 18.4 6.6 9.6 19.3 9.3 8.8 11.6 37.1 17.4 4.4 0.2 0.6 0.4 0.1 0.2 0.1 0.5 0.6 0.0 0.9 0.9 0.7 0.3 0.3 0.1 1.0 0.8 0.5 1.9 2.4 2.6 2.3 1.8 1.9 2.8 4.6 2.0 1.8 2.5 3.2 2.1 3.2 2.6 4.2 3.1 0.9 1.6 7.0 2.8 19.5 6.2 8.8 3.0 0.0 16.6 1.8 27.1 7.7 9.4 13.9 0.0 1.7 17.3 141.9 7.7 2.3 69.4 80.2 2.7 1.0 5.9 5.9 11.7 4.5 2.5 21.4 2.2 1.5 4.0 5.0 2.5 12.8 14.2 1.6 1.9 32.5 5.3 6.2 0.0 0.0 1.3 5.9 5.2 1.5 4.2 1.2 4.1 2.6 4.8 2.0 3.0 0.7 164.1 28.2 0.0 2.6 5.5 80.8 45.3 8.5 1.4 1.4 3.7 3.9 16.8 0.9 C2orf69 FLJ38973 ENSG00000178074 "Chromosome 2 open reading frame 69" Q8N8R5 2 199911293-199955935 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 132.1;Spermatocytes: 124.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045225 Approved "Secreted to blood" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 18: U-2197 - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA045225: AB_10960841" "unprognostic (6.94e-3)" "unprognostic (1.09e-1)" "unprognostic (7.17e-2)" "unprognostic (3.15e-2)" "unprognostic (1.16e-1)" "unprognostic (1.95e-1)" "unprognostic (4.39e-3)" "unprognostic (1.92e-2)" "unprognostic (5.58e-2)" "unprognostic (1.02e-2)" "unprognostic (6.33e-3)" "unprognostic (1.74e-1)" "unprognostic (1.44e-1)" "unprognostic (3.41e-3)" "unprognostic (8.87e-2)" "unprognostic (1.03e-2)" "unprognostic (5.86e-2)" 9.7 14.1 8.5 6.8 8.7 22.1 7.4 7.7 12.4 5.7 6.3 8.0 8.4 6.4 6.5 6.8 3.8 6.2 6.7 9.6 9.2 8.9 10.0 6.0 7.3 7.7 8.3 4.8 8.2 9.2 4.1 5.3 7.8 6.5 8.0 10.4 6.2 4.7 9.1 6.4 7.4 7.6 8.4 7.0 7.1 14.7 9.3 5.2 6.7 9.8 7.4 6.8 4.0 10.0 16.1 7.2 13.2 18.0 18.2 22.8 22.3 22.6 13.5 15.0 17.7 16.3 11.4 13.2 12.9 16.0 15.9 12.8 14.1 12.0 25.1 19.8 12.8 20.4 12.4 20.8 10.6 20.7 24.2 11.8 10.5 17.2 14.9 8.1 17.0 8.8 14.9 25.5 25.6 13.9 11.6 18.1 19.4 7.1 19.1 11.0 17.2 11.9 14.8 16.4 21.5 9.4 10.9 8.1 17.4 16.9 12.0 17.7 14.9 23.3 19.0 26.2 18.2 16.7 29.0 13.0 18.6 13.1 12.0 5.4 2.7 7.2 3.6 3.5 5.2 3.1 4.0 3.4 2.4 3.0 4.2 4.5 2.3 2.0 2.7 1.3 4.1 2.8 8.5 8.7 7.7 12.4 9.6 9.2 7.7 8.3 7.8 8.4 9.3 10.0 13.5 3.2 5.1 12.4 22.9 38.0 29.8 8.8 9.1 21.8 10.1 3.7 11.4 12.8 7.6 16.5 29.2 13.3 11.0 16.4 27.4 12.8 132.1 7.9 10.2 16.1 18.6 27.8 19.4 18.3 18.0 17.0 13.7 7.1 8.2 14.8 23.6 19.7 11.8 13.5 13.9 16.9 10.2 18.0 32.1 78.1 13.4 13.4 16.0 12.2 14.0 56.5 12.3 12.5 27.0 14.6 9.3 21.8 8.6 24.6 18.1 20.4 11.8 26.5 19.7 14.0 14.9 124.3 44.1 15.7 44.9 9.9 18.1 11.1 17.5 19.5 CA2 "CA-II, CAII, Car2" ENSG00000104267 "Carbonic anhydrase 2" P00918 8 85463968-85481493 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "Disease variant, FDA approved drug targets, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 687.4;stomach 1: 1108.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1773.2;Erythroid cells: 2448.1;Gastric mucus-secreting cells: 1380.7;Muller glia cells: 1536.4;Paneth cells: 781.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 51.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 263.8;HEK 293: 1097.8;THP-1: 461.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001550, CAB010102" Enhanced NA Yes 570000000 "Cluster 38: Basophils - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" "CAB010102: AB_626796, HPA001550: AB_1078393" "unprognostic (6.78e-2)" "unprognostic (3.06e-2)" "unprognostic (1.05e-2)" "unprognostic (1.63e-1)" "unprognostic (2.59e-1)" "unprognostic (9.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.72e-2)" "unprognostic (1.07e-1)" "unprognostic (5.23e-2)" "unprognostic (1.57e-1)" "unprognostic (9.89e-2)" "prognostic favorable (5.57e-6)" "unprognostic (2.45e-1)" "unprognostic (2.03e-1)" "unprognostic (1.32e-1)" "unprognostic (6.49e-3)" 7.4 10.1 95.9 36.8 127.5 246.8 37.9 122.1 143.8 5.0 444.0 687.4 285.2 2.9 10.6 19.8 2.7 112.7 15.9 105.2 107.8 331.2 273.5 43.1 6.6 115.5 112.0 0.4 55.1 10.1 6.1 19.6 114.2 1.9 643.6 390.4 74.7 68.4 42.7 81.0 31.3 32.3 98.2 8.4 1108.7 21.2 115.6 5.1 15.9 62.8 4.3 2.9 5.2 145.5 3.7 2.8 12.2 0.0 0.1 0.0 31.2 0.0 0.0 0.0 0.0 15.1 0.9 0.0 9.5 0.0 0.1 263.8 37.4 13.2 0.0 0.0 1097.8 35.8 17.0 0.5 0.0 23.7 5.1 0.0 63.9 0.0 3.7 0.0 0.0 0.0 0.3 0.2 0.0 0.4 0.4 41.4 3.7 86.5 0.0 21.2 1.3 0.5 3.7 8.8 0.2 0.3 5.0 0.0 0.1 9.6 0.0 461.5 0.0 0.0 6.6 0.0 0.4 0.4 1.0 0.1 1.8 0.1 0.0 51.2 5.3 8.6 0.2 15.0 7.4 1.3 0.1 0.8 15.4 3.0 0.0 0.0 12.6 0.1 13.4 1.4 0.0 33.3 95.9 127.5 122.1 143.8 105.2 107.8 115.5 112.0 114.2 98.2 115.6 145.5 19.4 16.0 79.9 34.0 19.6 90.6 1.3 152.5 17.6 23.1 56.9 18.4 19.8 430.4 22.4 161.8 64.6 15.2 2.4 1773.2 348.3 60.1 65.9 3.3 1.3 26.7 30.5 2448.1 1.4 11.3 403.1 6.4 1380.7 8.3 15.9 0.4 4.2 135.6 35.4 13.5 22.3 116.0 10.2 11.0 216.5 232.1 3.4 51.8 74.7 6.5 6.6 1536.4 1.0 3.0 226.4 16.1 781.9 2.2 10.3 3.5 0.3 468.2 3.9 66.1 0.0 12.1 8.2 3.1 2.8 31.2 111.7 17.1 11.7 0.7 390.8 0.5 CALM2 "CAMII, PHKD" ENSG00000143933 "Calmodulin 2" P0DP24 2 47160083-47176921 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007790, HPA044999" Approved NA Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB007790: AB_562257, HPA044999: AB_2679177" "prognostic unfavorable (5.05e-4)" "unprognostic (2.94e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.84e-4)" "unprognostic (9.21e-2)" "unprognostic (2.04e-3)" "prognostic unfavorable (8.35e-5)" "unprognostic (1.63e-2)" "unprognostic (4.67e-3)" "unprognostic (1.79e-2)" "unprognostic (1.97e-2)" "unprognostic (1.24e-2)" "unprognostic (1.14e-1)" "unprognostic (1.18e-2)" "unprognostic (2.29e-2)" "prognostic favorable (1.94e-5)" "unprognostic (1.24e-1)" 509.3 652.1 1177.9 334.4 1219.1 240.3 686.1 1229.7 1745.6 420.1 988.8 683.9 549.8 507.6 551.1 366.8 526.5 390.8 443.0 1229.0 1219.0 445.7 493.1 505.6 427.9 1209.1 1192.8 416.1 213.3 332.3 441.3 468.9 1227.6 449.1 706.0 574.8 490.8 561.5 262.9 304.2 621.2 634.7 1209.4 643.0 390.4 508.8 1257.9 571.0 443.3 258.1 467.2 459.0 340.2 1411.8 2459.6 905.8 1062.2 459.7 579.4 679.5 655.8 2177.2 1504.3 1437.1 1240.1 958.1 923.2 956.1 979.5 1753.2 1030.4 624.7 878.3 855.6 1907.0 729.3 438.6 821.6 526.6 1409.6 779.5 996.3 686.2 381.2 825.0 1265.3 1347.0 1230.4 977.3 312.8 812.1 854.7 3485.7 635.9 1270.2 984.3 801.3 2961.6 488.6 314.3 1142.9 1021.9 1631.0 441.0 756.8 2016.6 726.5 756.0 1120.1 1144.3 573.7 556.7 1084.8 1060.8 1135.8 627.0 1703.6 648.8 529.1 1038.2 718.8 711.3 1357.7 944.7 447.6 776.8 139.7 844.1 177.2 285.6 203.4 213.2 354.0 182.1 173.7 201.6 417.9 277.1 761.4 445.6 227.4 496.5 1177.9 1219.1 1229.7 1745.6 1229.0 1219.0 1209.1 1192.8 1227.6 1209.4 1257.9 1411.8 597.4 1387.8 613.5 195.2 570.7 1780.5 1101.0 2616.3 524.8 654.3 844.4 572.9 639.6 581.9 1751.8 759.6 98.0 931.4 649.8 906.5 2304.8 1977.0 312.7 889.1 363.8 652.0 597.1 697.1 317.5 683.4 627.9 943.6 354.8 452.5 665.4 484.5 280.6 536.6 1267.1 341.6 179.0 1020.1 3352.8 867.1 1858.2 287.0 1055.3 911.0 1771.6 143.4 1167.2 2063.1 350.1 129.7 339.8 2584.9 1114.4 863.6 309.7 1016.8 1231.6 1020.2 3245.3 334.2 907.2 671.6 1882.0 2193.5 714.3 503.0 1663.1 255.3 669.1 615.4 771.1 1062.2 CANT1 "SCAN-1, SHAPY" ENSG00000171302 "Calcium activated nucleotidase 1" Q8WVQ1 17 78991716-79009867 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 139.5;Intestinal goblet cells: 155.6;Syncytiotrophoblasts: 101.5;Undifferentiated cells: 100.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 445.4;T-47d: 282.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019627, HPA019639, HPA022818" Enhanced Supported "Golgi apparatus" NA Yes 3300000 "Cluster 52: Eosinophils - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus" "HPA019627: AB_1845969, HPA019639: AB_1845970, HPA022818: AB_1845971" "unprognostic (1.98e-2)" "unprognostic (2.49e-2)" "unprognostic (1.50e-2)" "unprognostic (5.36e-2)" "unprognostic (2.13e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (1.41e-4)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.76e-1)" "unprognostic (9.00e-2)" "unprognostic (3.30e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (6.21e-4)" "unprognostic (7.04e-2)" "unprognostic (5.06e-2)" "unprognostic (1.16e-1)" "unprognostic (7.23e-2)" 15.8 23.9 10.4 24.7 12.4 19.1 25.4 13.6 11.3 32.3 13.8 89.2 51.9 17.4 8.7 44.8 18.2 25.2 17.0 11.1 12.6 16.1 17.3 16.4 15.2 14.6 14.5 14.6 19.6 24.5 17.5 25.9 13.9 71.8 82.8 7.4 62.7 32.4 14.9 14.9 55.5 15.5 13.8 26.5 51.1 20.7 14.5 14.7 13.9 12.4 15.1 16.7 21.7 17.8 106.5 112.1 31.9 46.3 29.7 35.2 38.9 66.0 51.3 66.7 55.9 53.8 99.6 25.3 36.1 46.1 83.0 53.7 27.1 49.8 68.4 43.0 46.4 33.7 34.1 45.9 25.0 33.0 51.6 33.7 32.4 62.7 34.2 40.9 116.1 42.5 42.3 43.2 46.4 58.4 50.2 19.8 22.1 445.4 103.1 27.6 51.8 29.8 29.8 53.5 45.6 45.4 33.9 227.2 50.2 50.3 282.6 38.6 56.6 101.9 90.5 46.4 83.1 48.9 43.8 24.3 64.4 24.9 65.3 6.3 4.0 8.7 5.5 4.4 5.7 3.9 4.3 4.8 3.8 2.5 4.1 4.1 17.4 3.1 3.0 2.7 3.6 4.6 10.4 12.4 13.6 11.3 11.1 12.6 14.6 14.5 13.9 13.8 14.5 17.8 12.6 28.9 20.6 5.9 11.8 16.6 15.3 16.8 6.8 6.4 49.9 16.3 13.3 14.3 15.1 12.9 14.6 36.6 8.9 139.5 3.9 34.7 14.0 10.7 13.1 16.3 51.0 15.2 4.1 28.8 39.4 13.5 38.2 19.0 5.7 20.0 41.7 14.4 24.9 5.0 5.2 155.6 16.2 12.4 9.5 15.7 11.8 14.2 14.2 3.7 18.1 8.1 11.3 5.0 10.2 37.7 55.8 7.5 16.6 33.4 39.4 6.7 9.7 8.7 6.6 9.5 13.3 23.9 5.8 12.0 13.1 101.5 11.1 11.3 100.2 19.4 CARHSP1 "CRHSP-24, CSDC1" ENSG00000153048 "Calcium regulated heat stable protein 1" Q9Y2V2 16 8852942-8869012 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 422.7" "Group enriched" "Detected in all" 7 "Early spermatids: 2062.2;Late spermatids: 6999.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051911 Enhanced NA Yes 280000 "Cluster 10: Basophils - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 14: REH - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "HPA051911: AB_2681660" "unprognostic (4.08e-1)" "unprognostic (4.99e-2)" "unprognostic (2.46e-1)" "unprognostic (1.33e-1)" "unprognostic (1.15e-1)" "unprognostic (2.08e-3)" "unprognostic (8.57e-2)" "unprognostic (1.88e-3)" "unprognostic (2.03e-1)" "unprognostic (3.29e-1)" "unprognostic (2.61e-1)" "unprognostic (7.19e-3)" "unprognostic (1.76e-3)" "unprognostic (5.94e-2)" "unprognostic (1.10e-1)" "unprognostic (2.61e-1)" "prognostic favorable (7.24e-4)" 101.4 132.5 49.4 33.7 75.0 70.0 67.7 46.8 58.4 101.7 46.5 46.4 31.3 38.2 13.5 193.7 51.0 33.8 48.2 50.1 50.8 109.6 188.2 116.7 46.9 56.1 49.7 68.5 54.8 9.8 33.2 59.2 51.2 35.3 25.6 3.0 110.7 13.9 17.4 34.5 47.1 24.2 47.6 56.7 52.5 422.7 51.0 59.6 35.9 21.3 59.4 45.8 101.7 60.4 84.2 134.8 200.2 40.3 52.1 83.0 98.9 110.7 93.5 92.9 117.8 95.4 224.6 109.1 70.2 83.5 70.9 82.0 79.3 87.9 65.4 87.9 102.1 34.5 108.1 369.8 177.5 59.2 84.6 181.7 40.0 91.8 60.7 87.8 92.6 241.5 94.5 136.1 120.5 152.0 313.5 147.6 124.6 89.0 82.2 367.0 245.9 179.3 75.5 56.0 119.0 153.2 104.9 106.1 104.0 112.4 134.9 60.3 99.9 77.8 144.9 94.6 57.4 67.6 77.4 135.0 173.9 71.9 134.9 81.6 29.6 35.8 25.8 14.3 16.1 17.5 25.0 25.3 25.8 28.6 17.0 23.7 89.2 41.6 19.0 47.4 62.8 20.8 49.4 75.0 46.8 58.4 50.1 50.8 56.1 49.7 51.2 47.6 51.0 60.4 166.3 25.6 9.1 19.6 48.9 42.7 67.2 158.4 22.8 8.0 71.4 38.0 6.0 221.6 86.4 82.8 6.2 141.5 65.1 152.6 54.8 619.1 2062.2 101.9 82.0 145.3 144.9 147.5 4.4 241.8 312.6 86.4 42.8 114.4 39.3 118.0 128.8 323.5 70.5 11.8 5.9 107.7 91.6 62.4 55.3 6999.5 96.3 36.1 58.7 9.4 66.5 7.7 121.5 8.0 25.6 340.0 179.5 73.0 63.9 139.3 174.2 479.0 70.9 11.2 111.7 31.2 95.5 72.7 52.7 84.2 42.1 153.5 65.1 17.0 108.4 169.8 CASP2 "ICH1, MGC2181, NEDD2, PPP1R57" ENSG00000106144 "Caspase 2" P42575 7 143288215-143307696 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 51.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012175, HPA050678" Approved Approved Nucleoplasm NA Yes "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "CAB012175: , HPA050678: AB_2681214" "unprognostic (6.96e-2)" "prognostic favorable (7.38e-4)" "unprognostic (2.74e-2)" "unprognostic (7.51e-2)" "unprognostic (4.24e-2)" "unprognostic (2.39e-2)" "prognostic unfavorable (2.34e-4)" "unprognostic (1.74e-2)" "unprognostic (1.34e-2)" "prognostic favorable (2.89e-4)" "unprognostic (1.91e-2)" "unprognostic (1.64e-1)" "prognostic unfavorable (5.01e-6)" "unprognostic (2.66e-3)" "unprognostic (9.48e-2)" "unprognostic (1.19e-1)" "unprognostic (1.64e-1)" 10.3 6.6 6.0 13.9 6.7 40.2 10.5 7.8 6.7 11.8 6.7 11.1 10.7 10.2 9.6 15.3 10.3 7.0 8.4 5.9 6.2 9.1 6.4 10.4 22.0 7.2 6.4 9.3 8.4 11.1 5.3 12.4 7.7 7.6 12.7 7.7 11.9 6.3 3.9 17.4 15.4 9.4 5.9 19.0 9.6 9.1 6.9 27.5 8.8 5.0 27.1 7.5 11.2 10.0 27.5 25.4 28.8 51.0 15.1 17.5 15.4 27.7 13.0 25.4 27.8 26.0 31.3 52.0 25.9 18.4 19.4 27.3 29.4 22.6 34.0 45.8 22.5 31.2 40.4 18.3 8.4 60.7 37.4 13.0 18.1 31.0 11.0 11.3 22.0 41.3 26.3 32.6 27.5 27.5 109.1 64.4 36.5 27.4 26.3 79.1 14.6 32.6 15.1 23.3 31.5 34.2 54.8 24.3 17.3 19.6 26.3 23.4 24.1 22.5 15.5 40.7 28.1 27.0 28.5 59.4 24.9 72.6 41.1 69.2 17.9 17.2 24.5 21.7 24.2 25.7 33.3 25.3 17.3 28.8 24.3 28.3 21.7 24.2 34.1 21.1 38.9 15.3 6.0 6.7 7.8 6.7 5.9 6.2 7.2 6.4 7.7 5.9 6.9 10.0 14.1 9.6 8.3 4.2 17.4 15.2 7.0 9.4 6.2 4.8 19.0 13.5 6.2 17.2 7.0 7.3 8.4 20.0 19.3 8.7 3.9 8.1 36.6 10.8 17.9 16.4 10.7 9.7 11.2 7.7 14.6 9.3 8.2 20.1 10.1 22.7 18.2 7.2 10.1 6.7 8.8 11.5 0.0 16.9 23.3 51.0 11.8 12.2 21.4 4.7 20.8 4.4 13.4 4.5 22.4 9.4 5.9 8.2 13.0 5.8 9.1 4.2 4.9 15.4 0.0 8.3 10.9 13.7 25.9 16.1 13.8 5.7 16.7 9.3 15.5 7.0 CBX3 HP1Hs-gamma ENSG00000122565 "Chromobox 3" Q13185 7 26201162-26213607 "Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001973, HPA004902" Supported Supported "Nucleoplasm,Nuclear bodies" NA Yes 180000 "Cluster 49: Eosinophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "CAB001973: , HPA004902: AB_1850635" "prognostic unfavorable (7.92e-4)" "unprognostic (1.43e-1)" "unprognostic (4.84e-2)" "unprognostic (1.12e-2)" "unprognostic (4.85e-2)" "unprognostic (9.25e-3)" "prognostic unfavorable (2.20e-8)" "unprognostic (2.13e-2)" "unprognostic (3.95e-2)" "unprognostic (3.71e-3)" "prognostic unfavorable (4.00e-4)" "unprognostic (1.16e-1)" "prognostic unfavorable (4.56e-7)" "unprognostic (7.79e-2)" "unprognostic (4.69e-2)" "unprognostic (1.17e-1)" "unprognostic (5.78e-2)" 76.2 93.0 55.5 99.2 57.8 168.8 98.5 58.8 74.1 65.0 56.6 75.3 105.8 76.7 79.7 63.9 62.9 58.5 64.2 54.2 63.2 87.6 84.9 62.1 145.7 60.2 61.0 79.5 56.3 51.5 40.5 88.8 60.7 56.6 87.2 122.7 61.3 59.8 87.2 54.7 99.0 65.9 60.2 82.0 61.7 99.6 58.2 190.4 55.3 68.6 140.4 84.1 55.7 63.6 365.4 156.3 330.0 332.2 115.0 205.8 257.8 275.9 209.1 205.2 207.2 185.8 296.8 544.1 218.7 183.9 440.6 283.0 275.7 231.2 332.1 151.8 209.1 312.8 201.0 208.5 126.1 508.3 294.7 153.9 197.5 163.2 231.2 253.9 281.7 343.2 506.1 263.9 351.7 207.5 489.4 625.9 424.4 311.3 225.1 313.6 303.9 452.3 303.8 201.4 401.1 448.2 230.5 482.6 274.9 345.3 412.4 455.1 212.0 186.0 340.5 222.1 376.8 394.6 596.5 929.3 163.2 422.3 864.3 135.7 85.9 137.7 77.3 116.3 96.9 86.8 114.4 96.1 89.1 77.7 118.4 119.6 92.6 99.2 123.2 72.4 148.3 87.2 55.5 57.8 58.8 74.1 54.2 63.2 60.2 61.0 60.7 60.2 58.2 63.6 139.1 109.0 98.4 16.3 158.5 143.6 93.3 128.0 105.3 101.8 223.8 181.0 124.1 133.0 119.7 64.4 77.2 176.3 138.7 111.2 140.8 167.6 162.2 132.4 215.4 142.6 110.2 306.6 27.4 141.4 362.1 123.6 81.1 129.0 222.0 166.2 145.3 289.2 143.1 50.5 26.8 156.6 107.8 254.9 200.0 41.9 136.4 157.6 104.9 15.0 183.3 155.9 166.9 23.1 35.8 166.3 103.8 98.2 129.1 135.1 112.6 187.4 107.3 132.1 78.9 60.0 110.1 274.5 388.6 112.5 107.8 270.8 155.2 133.1 205.9 110.9 CBX6 ENSG00000183741 "Chromobox 6" O95503 22 38861422-38872249 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 88.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048653 Uncertain Approved Nucleoplasm,Mitochondria NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Mitochondria" "HPA048653: AB_2680479" "unprognostic (1.65e-2)" "unprognostic (8.66e-2)" "unprognostic (6.20e-3)" "unprognostic (3.14e-3)" "unprognostic (1.56e-1)" "unprognostic (2.62e-1)" "prognostic unfavorable (8.30e-4)" "unprognostic (2.90e-2)" "unprognostic (3.72e-3)" "unprognostic (5.97e-2)" "prognostic favorable (2.46e-6)" "unprognostic (2.75e-1)" "unprognostic (1.27e-3)" "unprognostic (7.39e-2)" "unprognostic (1.03e-1)" "unprognostic (1.94e-1)" "unprognostic (2.26e-2)" 16.3 22.4 67.1 16.5 53.6 28.3 12.3 9.9 83.6 21.0 0.0 39.3 6.5 34.0 14.5 13.3 27.0 11.3 17.7 88.2 10.1 18.7 6.3 17.2 14.2 16.6 14.0 24.4 17.1 49.5 27.5 4.3 10.0 22.0 7.2 8.5 13.7 25.9 8.9 8.2 17.1 26.1 5.5 15.9 20.5 4.3 21.8 12.5 19.0 6.7 15.3 31.0 11.9 30.8 40.3 41.7 9.1 31.3 68.5 38.2 2.8 42.8 24.5 21.8 20.3 21.1 36.5 65.3 31.2 29.5 15.3 46.8 17.0 18.3 11.9 63.1 53.0 6.7 18.5 7.4 37.2 32.6 31.1 57.0 9.1 49.7 23.5 30.1 24.9 18.4 14.9 32.2 15.1 45.5 20.2 9.5 8.1 23.1 31.9 29.9 30.5 25.9 31.3 37.4 44.3 9.8 27.5 36.4 23.7 3.2 25.0 19.3 32.7 18.9 57.9 33.2 29.6 32.9 34.1 23.5 37.0 33.6 40.1 2.2 9.1 4.7 18.6 12.4 15.3 6.7 12.6 13.1 9.1 7.7 10.3 12.6 4.0 9.1 12.5 46.1 8.0 20.0 67.1 53.6 9.9 83.6 88.2 10.1 16.6 14.0 10.0 5.5 21.8 30.8 30.5 16.0 14.7 9.8 25.1 33.9 47.4 18.4 16.5 100.4 42.6 31.6 27.5 52.9 22.1 73.5 39.6 12.4 83.0 9.6 35.2 102.6 1.1 6.9 46.0 36.4 122.7 17.7 28.9 50.1 2.0 48.5 3.1 17.5 6.3 18.7 46.8 32.4 19.8 124.5 27.3 3.2 30.5 40.8 121.1 2.9 74.3 33.2 81.8 14.0 91.1 91.2 57.7 15.1 23.3 46.9 9.1 80.9 24.5 58.9 0.1 51.7 18.0 59.4 72.3 54.4 85.1 4.2 6.8 10.4 34.0 4.7 35.8 40.9 0.9 82.6 CCDC14 "DKFZp434L1050, FLJ12892" ENSG00000175455 "Coiled-coil domain containing 14" Q49A88 3 123897305-123961408 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035278, HPA035279" Uncertain Enhanced "Centriolar satellite" NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Centriolar satellite" "HPA035278: AB_2674548, HPA035279: AB_10601253" "unprognostic (7.41e-3)" "unprognostic (5.18e-2)" "unprognostic (1.86e-1)" "unprognostic (1.41e-1)" "unprognostic (9.45e-2)" "prognostic favorable (5.27e-4)" "prognostic unfavorable (4.82e-4)" "unprognostic (6.83e-2)" "unprognostic (5.50e-2)" "unprognostic (2.12e-1)" "unprognostic (3.76e-1)" "prognostic unfavorable (4.76e-4)" "prognostic unfavorable (3.50e-8)" "unprognostic (2.14e-2)" "unprognostic (2.86e-1)" "unprognostic (9.37e-2)" "prognostic favorable (2.72e-5)" 11.8 9.6 5.3 12.8 8.5 36.6 21.4 6.4 7.5 17.1 4.6 22.5 12.8 22.1 35.5 10.0 14.5 13.6 8.6 5.1 8.7 14.4 15.3 13.7 16.6 8.8 7.5 17.4 16.8 5.6 13.7 10.6 9.0 16.3 34.8 43.2 14.9 7.9 6.2 23.8 15.4 14.2 7.7 12.4 13.9 23.7 10.1 20.5 13.2 2.9 15.0 12.0 12.4 10.0 42.6 22.5 72.1 28.0 10.6 16.1 34.0 79.9 26.2 41.6 45.2 17.5 28.5 12.4 19.9 19.1 30.1 44.5 27.1 14.8 55.9 10.5 20.0 49.9 50.7 17.7 9.0 31.2 29.9 15.1 9.7 20.7 21.9 49.0 19.7 48.9 25.8 21.0 28.1 18.3 26.4 17.3 22.2 19.0 28.0 47.2 29.0 15.2 23.3 34.1 25.4 28.3 45.2 13.0 33.4 46.5 27.5 31.2 22.9 91.1 45.8 28.5 26.5 20.0 15.8 32.8 32.2 25.6 31.5 1.1 0.6 1.3 1.4 0.9 1.0 0.8 1.2 1.2 0.3 0.7 1.3 1.1 0.1 2.5 0.2 1.8 2.6 0.7 5.3 8.5 6.4 7.5 5.1 8.7 8.8 7.5 9.0 7.7 10.1 10.0 22.1 22.4 71.5 72.8 21.3 21.9 36.4 31.2 25.6 35.9 48.9 37.7 14.6 38.6 29.4 36.8 60.5 27.5 27.6 67.9 0.0 26.1 38.6 33.7 44.0 23.8 89.7 72.1 83.8 13.8 22.9 32.3 26.0 29.9 25.9 67.9 28.5 22.3 20.9 28.6 67.7 85.6 67.1 19.7 29.9 17.3 32.6 21.0 24.9 41.2 20.1 18.6 49.4 91.0 77.1 22.8 63.7 31.2 25.3 20.4 41.6 12.6 18.9 75.5 19.7 39.2 29.4 144.0 49.6 18.2 16.1 11.6 30.3 33.5 77.7 22.9 CCDC77 MGC13183 ENSG00000120647 "Coiled-coil domain containing 77" Q9BR77 12 389273-442642 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 24.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038854 Approved Approved "Nuclear membrane" NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 5: NTERA-2 - Transcription" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear membrane" "HPA038854: AB_10673121" "unprognostic (3.25e-1)" "unprognostic (2.32e-1)" "unprognostic (1.56e-1)" "unprognostic (1.76e-3)" "unprognostic (7.26e-3)" "unprognostic (2.34e-1)" "prognostic unfavorable (8.11e-7)" "unprognostic (2.54e-2)" "unprognostic (3.41e-3)" "unprognostic (2.89e-1)" "unprognostic (3.82e-1)" "unprognostic (2.62e-1)" "unprognostic (4.11e-3)" "unprognostic (1.27e-2)" "unprognostic (1.08e-1)" "unprognostic (3.19e-2)" "unprognostic (4.41e-3)" 3.4 5.0 3.1 6.2 4.9 4.6 4.5 3.1 4.9 3.6 1.8 4.1 4.6 5.0 2.2 4.1 3.8 3.2 3.1 3.9 4.6 3.8 3.4 3.9 6.8 4.5 4.1 5.2 2.5 2.3 2.4 3.6 4.3 3.5 4.7 3.4 3.0 2.6 4.7 5.2 3.6 3.4 2.8 4.8 3.3 12.5 3.9 9.7 4.0 3.2 6.2 3.1 3.6 7.7 10.0 13.2 28.7 18.9 9.5 8.1 29.4 24.7 11.6 23.3 37.4 13.4 17.1 23.8 5.9 9.8 13.6 13.6 20.5 7.2 25.0 52.0 20.1 26.9 26.5 17.8 5.5 22.2 12.9 6.5 4.3 21.9 13.5 14.0 15.6 22.7 22.4 24.2 23.9 6.0 21.6 15.7 57.0 13.8 9.9 24.4 51.8 14.7 8.7 7.3 8.2 21.1 24.5 9.4 12.9 42.4 7.4 16.7 14.8 11.6 22.5 20.6 29.0 6.8 13.9 29.8 15.7 22.0 20.3 2.5 4.5 3.9 4.7 6.4 4.9 5.9 4.3 5.2 4.8 8.1 3.0 4.5 3.4 6.2 8.1 5.2 3.3 3.1 3.1 4.9 3.1 4.9 3.9 4.6 4.5 4.1 4.3 2.8 3.9 7.7 4.6 0.0 6.2 2.6 9.4 4.1 3.6 3.5 3.4 3.1 4.1 4.4 3.7 2.8 4.4 3.7 6.2 6.8 8.6 2.9 7.9 3.2 24.2 5.6 5.5 4.4 2.4 5.0 8.1 2.0 8.0 4.7 6.6 4.5 7.0 8.1 3.6 2.3 5.5 1.7 7.9 4.5 8.2 6.6 2.9 15.3 4.1 5.5 1.8 3.7 6.0 6.5 8.2 8.0 13.7 2.0 5.9 4.5 7.0 2.6 2.0 3.4 5.4 5.5 6.6 7.4 4.3 22.3 18.0 6.7 3.8 5.6 6.6 4.4 4.1 2.2 CCNA2 "CCN1, CCNA" ENSG00000145386 "Cyclin A2" P20248 4 121816444-121823883 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.6;lymphoid tissue: 46.9;retina: 31.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 47.9;Erythroid cells: 102.1;Extravillous trophoblasts: 92.8;Plasma cells: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 3.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 3.4;white matter: 7.6" "CAB000114, HPA020626" Enhanced Enhanced Nucleoplasm,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "CAB000114: AB_563675, HPA020626: AB_1847376" "unprognostic (4.02e-2)" "unprognostic (1.93e-1)" "unprognostic (7.66e-3)" "prognostic unfavorable (8.78e-4)" "unprognostic (1.25e-1)" "unprognostic (1.67e-2)" "prognostic unfavorable (9.17e-5)" "prognostic unfavorable (4.27e-4)" "unprognostic (3.92e-3)" "unprognostic (2.65e-2)" "prognostic unfavorable (4.43e-6)" "unprognostic (8.38e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.65e-1)" "unprognostic (1.82e-1)" "unprognostic (6.07e-2)" "unprognostic (1.59e-1)" 1.5 1.2 2.5 11.4 2.5 38.6 2.5 3.5 4.7 4.3 2.5 9.8 10.1 2.5 0.6 8.4 2.2 1.8 1.3 2.3 2.4 1.5 1.6 1.8 25.0 2.8 2.7 3.8 0.8 0.6 2.7 10.5 2.6 1.9 11.5 31.7 1.8 0.8 0.7 6.7 9.9 4.0 2.6 4.6 4.4 6.2 2.6 46.9 1.2 0.5 24.4 2.9 3.9 3.5 177.1 45.3 120.5 51.8 6.4 16.3 98.8 119.7 52.8 156.7 115.6 99.4 106.5 161.2 31.7 63.8 55.0 58.0 154.2 71.1 128.0 77.8 70.8 129.7 56.0 96.9 1.5 197.0 88.0 4.2 5.3 65.1 38.7 24.7 95.4 84.3 187.9 156.9 126.1 63.8 251.8 113.1 95.5 109.9 49.8 114.1 233.5 78.2 44.8 34.6 51.0 53.8 63.1 76.0 32.4 89.8 63.7 81.9 56.5 72.7 109.3 77.4 115.9 98.0 112.3 181.9 41.5 197.6 82.4 0.0 0.1 0.3 0.1 0.0 0.0 0.1 0.9 0.6 0.4 0.0 0.0 0.2 0.1 0.8 0.1 0.0 3.1 0.9 2.5 2.5 3.5 4.7 2.3 2.4 2.8 2.7 2.6 2.6 2.6 3.5 0.8 0.0 1.1 1.6 5.7 2.8 1.5 5.5 1.8 2.9 1.9 1.8 0.8 0.0 1.6 0.0 12.5 47.9 1.9 4.9 0.0 0.7 9.6 0.6 2.7 3.3 1.2 102.1 3.3 0.2 92.8 6.3 9.2 2.1 0.0 18.1 4.2 0.9 25.3 0.0 4.1 7.7 8.2 6.9 3.6 2.1 0.9 3.6 1.8 2.8 0.2 1.2 0.0 4.5 5.2 0.5 3.1 1.2 35.5 3.3 1.8 0.2 2.5 14.2 0.0 0.9 6.0 10.3 17.7 24.0 1.3 8.5 6.3 1.4 19.9 2.1 CCNB1 CCNB ENSG00000134057 "Cyclin B1" P14635 5 69167135-69178245 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 52.9;lymphoid tissue: 76.2" "Cell type enriched" "Detected in many" 6 "Extravillous trophoblasts: 723.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 3.0;white matter: 8.3" "Not detected" "Not detected" "CAB000115, CAB003804, HPA030741, HPA061448" Enhanced Enhanced Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "CAB000115: , CAB003804: AB_562272, HPA030741: AB_2673586, HPA061448: AB_2684522" "unprognostic (4.12e-2)" "unprognostic (2.75e-2)" "unprognostic (1.91e-3)" "unprognostic (4.08e-3)" "unprognostic (2.78e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.54e-7)" "prognostic unfavorable (3.38e-4)" "unprognostic (1.43e-2)" "unprognostic (1.63e-2)" "unprognostic (2.49e-3)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.11e-16)" "unprognostic (2.44e-1)" "unprognostic (3.73e-1)" "unprognostic (1.44e-1)" "unprognostic (5.15e-3)" 4.0 5.1 4.0 26.0 3.9 52.9 10.0 6.0 4.9 6.3 2.8 22.2 20.9 7.7 5.4 36.0 8.2 4.0 3.0 3.8 4.0 4.8 4.3 3.9 54.5 6.2 4.4 5.0 4.2 5.8 2.6 20.8 6.5 3.8 29.5 5.7 6.5 3.9 3.4 14.5 19.5 14.4 3.5 11.1 10.8 32.9 5.2 76.2 9.3 2.0 67.0 8.4 10.4 4.0 466.0 317.1 423.5 377.1 22.2 37.1 980.2 201.3 150.8 521.3 437.0 471.2 423.9 285.2 239.1 187.6 594.2 284.2 432.4 442.8 577.2 281.4 217.2 181.6 243.2 323.2 6.8 160.5 197.7 16.6 27.7 300.5 207.2 47.7 282.8 274.2 223.5 217.9 430.2 441.4 220.5 184.7 236.7 153.3 199.3 228.4 305.2 288.2 192.6 168.2 212.7 133.5 347.7 160.3 141.9 236.4 306.4 162.5 119.8 114.4 368.5 207.6 510.2 109.2 216.6 399.8 158.8 271.9 358.6 3.1 2.0 1.5 3.2 5.1 4.5 15.4 8.3 7.4 6.0 11.1 2.7 2.6 1.3 8.2 2.4 5.0 17.6 6.2 4.0 3.9 6.0 4.9 3.8 4.0 6.2 4.4 6.5 3.5 5.2 4.0 4.0 0.0 0.5 2.0 11.8 11.5 7.2 32.1 4.6 4.8 9.8 12.3 1.9 1.5 8.8 5.5 2.1 108.2 8.3 9.5 1.9 6.5 110.2 15.2 7.4 6.6 1.2 76.2 2.7 1.4 723.1 18.3 21.4 13.0 2.5 63.0 8.9 3.2 60.2 0.0 2.1 13.8 73.2 12.0 7.2 17.8 3.1 9.7 3.6 1.0 2.7 3.9 2.1 0.5 1.0 2.4 1.5 2.6 24.1 4.5 2.5 5.6 13.1 4.1 6.6 4.9 18.5 74.3 62.2 37.4 7.2 41.5 8.0 11.8 33.4 7.8 CCNB2 HsT17299 ENSG00000157456 "Cyclin B2" O95067 15 59105126-59125045 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 74.6;lymphoid tissue: 73.1;testis: 69.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 67.9;Early spermatids: 228.5;Erythroid cells: 123.6;Extravillous trophoblasts: 128.3;Spermatocytes: 288.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 5 "T-reg: 22.7" "Lineage enriched" "Detected in many" 6 "T-cells: 22.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA008873, CAB009575" Enhanced Enhanced "Golgi apparatus,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Golgi apparatus" "CAB009575: AB_2072392, HPA008873: AB_1078604" "unprognostic (2.69e-2)" "unprognostic (2.25e-1)" "unprognostic (4.43e-2)" "unprognostic (1.96e-2)" "unprognostic (1.77e-1)" "unprognostic (4.65e-2)" "prognostic unfavorable (2.83e-4)" "prognostic unfavorable (4.63e-4)" "prognostic unfavorable (3.21e-5)" "unprognostic (1.09e-1)" "prognostic unfavorable (1.74e-5)" "unprognostic (4.48e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.96e-1)" "unprognostic (1.41e-1)" "unprognostic (3.98e-2)" "unprognostic (4.44e-1)" 1.0 1.1 0.4 12.2 1.1 74.6 2.9 0.7 0.7 2.9 1.1 14.3 14.1 2.6 0.3 16.1 1.1 1.9 0.7 0.6 0.7 1.1 1.4 2.2 33.0 1.3 1.0 0.8 0.7 0.2 0.3 11.4 1.0 1.6 16.8 0.3 2.8 0.4 0.7 9.4 12.0 6.4 0.7 7.1 5.6 69.4 1.1 73.1 1.0 0.4 43.7 3.6 5.6 2.2 132.5 112.1 188.6 47.1 8.5 16.6 97.5 104.8 69.9 165.2 135.6 187.8 81.1 122.1 75.4 71.8 97.2 160.1 181.4 92.6 157.8 124.1 92.4 153.1 127.3 108.1 2.5 118.1 98.6 6.3 12.6 71.4 91.9 32.7 114.1 147.0 163.1 194.5 128.2 96.5 137.9 177.2 138.6 58.5 65.2 157.5 260.0 124.4 53.3 91.9 115.2 75.9 148.9 80.2 97.3 147.9 139.4 120.4 58.5 81.6 134.4 90.5 210.5 84.2 133.2 213.8 53.6 267.1 117.9 0.0 0.1 0.7 0.1 0.0 0.3 2.1 4.6 5.0 3.0 1.7 0.0 0.1 0.8 3.6 0.1 0.1 22.7 2.1 0.4 1.1 0.7 0.7 0.6 0.7 1.3 1.0 1.0 0.7 1.1 2.2 0.3 0.0 0.6 0.0 6.8 4.8 2.8 11.5 1.8 0.2 2.5 3.3 0.5 0.0 3.2 0.0 0.0 67.9 1.6 4.1 0.0 0.7 228.5 5.3 3.1 3.9 3.0 123.6 0.7 0.2 128.3 7.2 7.1 5.9 0.0 29.9 6.1 1.1 29.9 0.0 0.8 10.1 20.3 10.6 3.3 53.5 4.4 7.9 0.0 0.0 2.4 0.2 1.0 0.0 1.4 0.4 1.9 1.9 18.7 2.3 2.1 0.0 1.8 0.3 0.0 1.0 5.7 288.7 32.1 20.3 6.1 16.3 4.4 4.1 23.4 5.0 CCND2 ENSG00000118971 "Cyclin D2" P30279 12 4269771-4305353 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 354.3;Granulosa cells: 438.5;Langerhans cells: 255.3;Plasma cells: 371.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 152.4;HBEC3-KT: 136.6;HDLM-2: 238.8;Karpas-707: 287.9;RH-30: 202.7;RPMI-8226: 114.2" "HPA049138, HPA054196" Approved Enhanced Nucleoplasm Yes Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA049138: AB_2680650, HPA054196: AB_2682412" "unprognostic (2.98e-3)" "unprognostic (1.15e-1)" "unprognostic (7.21e-2)" "unprognostic (1.65e-2)" "unprognostic (1.70e-2)" "unprognostic (4.82e-2)" "unprognostic (4.94e-2)" "unprognostic (2.01e-3)" "unprognostic (3.16e-2)" "unprognostic (1.66e-2)" "prognostic favorable (2.52e-4)" "unprognostic (1.75e-1)" "unprognostic (1.25e-1)" "unprognostic (8.23e-2)" "unprognostic (4.52e-1)" "prognostic favorable (9.76e-5)" "unprognostic (7.06e-2)" 20.0 52.6 5.4 8.7 12.9 20.3 13.0 0.0 13.5 26.9 0.0 40.8 17.4 26.1 7.5 12.2 22.1 2.7 51.9 14.4 1.1 9.7 1.9 17.2 5.3 9.6 0.2 14.2 24.5 9.9 23.5 12.9 2.7 20.7 10.4 0.7 10.8 9.1 1.8 12.6 25.9 9.8 7.8 19.7 12.7 4.0 0.0 3.2 20.3 0.0 5.1 26.5 19.9 4.5 0.0 0.0 152.4 0.0 10.1 0.4 0.0 0.0 0.0 0.0 0.0 62.8 0.0 0.0 0.4 0.0 0.0 16.2 0.1 136.6 0.0 238.8 2.5 0.7 0.0 0.0 0.0 57.0 12.6 23.8 2.4 0.0 97.0 0.0 0.0 0.8 17.0 287.9 6.8 0.0 0.0 52.8 50.8 0.0 0.0 0.0 202.7 114.2 0.0 8.1 0.0 0.0 0.0 0.0 0.0 89.6 0.0 0.0 4.2 0.0 39.3 0.0 0.0 1.4 60.7 0.0 0.0 32.3 0.0 6.6 0.4 4.7 11.1 0.0 17.1 3.1 16.3 13.8 0.4 1.7 10.4 12.1 1.1 9.4 0.0 1.1 13.6 6.8 5.4 12.9 0.0 13.5 14.4 1.1 9.6 0.2 2.7 7.8 0.0 4.5 23.9 60.9 46.6 10.1 82.9 106.8 23.9 73.4 174.2 7.6 3.4 41.8 354.3 2.8 37.4 12.9 0.0 4.0 128.7 37.5 0.0 3.1 0.8 3.3 110.8 35.7 64.8 37.2 54.1 68.3 2.7 123.6 4.6 3.6 55.8 438.5 19.6 2.2 13.0 3.3 55.2 147.7 12.2 11.9 255.3 3.3 52.5 39.3 39.2 19.7 9.8 170.0 89.6 55.3 4.0 20.7 49.4 124.1 371.2 35.8 34.4 1.4 10.3 6.5 26.3 21.4 112.6 0.8 5.1 50.9 39.6 6.3 122.6 41.5 159.7 8.4 CCND3 ENSG00000112576 "Cyclin D3" P30281 6 41934934-42050357 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 256.6" "Cell type enhanced" "Detected in all" "NK-cells: 555.1;Syncytiotrophoblasts: 236.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 696.3;REH: 651.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000116, HPA042871" Approved Supported Nucleoplasm NA Yes "Cluster 10: Basophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "CAB000116: , HPA042871: " "unprognostic (4.53e-2)" "unprognostic (4.45e-2)" "unprognostic (2.45e-1)" "unprognostic (4.40e-3)" "unprognostic (1.01e-1)" "unprognostic (9.80e-2)" "unprognostic (3.40e-2)" "unprognostic (5.25e-2)" "unprognostic (7.76e-2)" "unprognostic (3.45e-1)" "unprognostic (9.17e-2)" "unprognostic (6.39e-2)" "unprognostic (2.45e-3)" "unprognostic (9.12e-2)" "unprognostic (1.71e-1)" "prognostic favorable (8.08e-6)" "unprognostic (2.11e-1)" 74.3 137.6 84.8 63.1 84.6 220.2 64.8 80.0 94.5 36.9 78.4 45.6 40.6 35.4 15.3 39.6 43.2 34.4 68.1 86.2 88.6 42.4 22.1 102.5 143.3 87.4 82.5 36.0 31.6 23.7 33.3 55.4 84.0 50.4 27.0 10.3 50.4 25.6 18.2 52.3 78.5 28.6 79.7 170.4 66.1 11.1 86.4 256.6 58.7 32.5 83.6 45.4 44.3 80.8 67.7 242.2 24.6 54.8 43.7 88.6 286.1 77.1 43.7 77.7 57.1 45.9 29.7 288.9 127.8 51.9 68.9 40.5 65.8 93.4 39.2 49.2 43.4 458.8 106.6 37.3 94.9 75.9 385.2 84.7 59.8 76.0 27.9 23.5 96.6 188.3 236.7 27.2 111.6 92.0 696.3 354.6 10.9 202.8 51.5 651.8 96.3 32.2 179.1 44.9 83.8 21.8 65.8 83.3 38.6 30.6 51.5 288.4 162.9 86.2 47.9 74.7 88.1 17.9 15.2 458.5 50.4 157.6 53.3 1281.3 246.3 725.1 390.4 294.4 276.5 127.1 266.4 318.1 343.3 180.8 306.4 328.3 339.3 333.2 405.6 221.4 193.0 635.4 84.8 84.6 80.0 94.5 86.2 88.6 87.4 82.5 84.0 79.7 86.4 80.8 102.2 60.9 67.9 31.0 102.9 27.0 95.8 52.3 48.9 19.6 49.9 45.1 26.2 64.3 27.8 20.2 6.2 201.0 227.3 66.4 29.4 20.3 12.8 12.1 10.8 68.3 9.6 133.6 37.1 24.3 82.4 32.3 19.9 11.2 26.6 7.7 70.6 7.2 45.3 11.8 23.7 19.5 50.8 115.7 51.7 9.4 41.3 152.2 37.4 47.8 79.0 40.8 555.1 18.1 9.3 29.9 30.5 51.9 48.7 40.3 18.6 19.8 22.5 16.2 46.0 19.2 31.9 4.3 6.3 21.7 22.6 236.6 195.0 141.6 32.7 52.8 CCNE1 CCNE ENSG00000105173 "Cyclin E1" P24864 19 29811991-29824312 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.8;placenta: 30.8" "Cell type enriched" "Detected in many" 14 "Extravillous trophoblasts: 1756.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "BEWO: 293.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000308, CAB016682, HPA018169" Approved Enhanced Nucleoplasm Yes Yes "Cluster 43: B-cells - Humoral immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "CAB000308: , CAB016682: AB_1614564, HPA018169: AB_1847384" "unprognostic (2.90e-3)" "unprognostic (1.33e-2)" "unprognostic (1.47e-3)" "prognostic unfavorable (6.35e-6)" "unprognostic (5.78e-2)" "unprognostic (4.77e-2)" "prognostic unfavorable (3.89e-5)" "unprognostic (1.26e-3)" "unprognostic (3.14e-3)" "prognostic unfavorable (2.97e-4)" "unprognostic (3.29e-2)" "unprognostic (7.07e-2)" "unprognostic (1.11e-16)" "unprognostic (5.61e-2)" "unprognostic (1.92e-1)" "unprognostic (6.63e-2)" "unprognostic (1.46e-1)" 1.2 5.7 1.9 4.3 2.1 35.8 0.8 2.8 2.7 1.0 0.9 3.9 3.0 1.4 0.6 4.4 0.9 1.0 2.3 2.0 2.5 1.0 0.7 1.1 6.1 2.0 2.1 0.8 1.8 2.8 0.9 30.8 2.0 1.0 4.7 2.0 1.5 1.4 2.1 4.1 2.5 2.2 1.7 4.2 2.1 12.1 2.5 4.5 1.6 1.8 7.8 3.0 1.8 2.3 15.6 31.8 24.3 34.0 5.2 6.0 293.1 24.7 5.3 10.8 13.2 33.0 31.2 13.3 55.9 11.1 14.0 4.9 28.8 12.8 15.2 41.9 17.7 11.2 30.0 34.5 4.1 44.0 28.7 6.2 7.1 14.8 1.9 3.4 13.3 13.2 45.6 5.8 16.8 24.4 24.5 13.0 40.1 36.2 7.2 36.2 28.6 10.1 8.4 24.6 20.5 17.4 35.4 42.7 3.9 35.4 9.5 32.7 8.0 25.0 92.8 14.9 16.9 24.1 18.2 91.6 13.8 5.6 13.7 0.0 0.0 0.0 0.1 0.5 0.3 0.6 0.1 0.0 0.4 0.0 0.0 0.2 0.4 0.0 0.5 0.0 0.3 0.1 1.9 2.1 2.8 2.7 2.0 2.5 2.0 2.1 2.0 1.7 2.5 2.3 3.1 0.0 0.6 0.7 4.8 4.8 1.5 0.3 2.2 2.9 8.2 11.3 3.1 0.0 1.4 0.0 0.0 122.4 3.7 3.5 0.0 0.4 14.6 7.5 4.1 1.9 3.0 30.7 2.9 0.7 1756.5 6.0 5.6 20.1 0.0 4.6 1.4 0.2 43.4 3.3 5.1 3.3 0.0 1.0 2.5 3.6 1.2 4.2 1.8 0.0 0.2 1.7 0.0 2.5 1.3 1.4 2.2 2.2 18.4 2.2 1.0 0.4 0.1 1.1 6.6 4.1 3.4 25.0 17.6 8.5 6.0 115.7 4.5 6.9 4.9 3.5 CCNE2 CYCE2 ENSG00000175305 "Cyclin E2" O96020 8 94879770-94896678 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 33.6;Oligodendrocytes: 34.5;Spermatocytes: 77.7;Spermatogonia: 26.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 5.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 101.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007825, CAB019374" Enhanced NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "CAB007825: AB_598148, CAB019374: " "unprognostic (1.80e-2)" "unprognostic (4.81e-2)" "unprognostic (7.49e-2)" "unprognostic (2.08e-2)" "unprognostic (2.36e-1)" "prognostic favorable (5.87e-4)" "unprognostic (8.37e-4)" "prognostic unfavorable (8.77e-4)" "unprognostic (3.18e-2)" "unprognostic (2.19e-2)" "unprognostic (3.64e-2)" "unprognostic (1.04e-2)" "unprognostic (7.01e-12)" "unprognostic (1.81e-2)" "unprognostic (1.50e-1)" "unprognostic (1.06e-2)" "unprognostic (3.03e-1)" 2.0 0.6 3.7 6.9 8.3 37.0 2.2 9.0 7.7 1.7 0.3 5.4 3.6 1.8 0.1 4.7 0.6 2.4 1.4 3.2 5.4 0.5 2.3 1.8 10.9 9.9 8.1 1.5 1.8 0.5 0.6 4.3 8.8 1.2 5.7 5.2 1.8 0.2 0.7 5.9 4.3 2.2 7.4 2.3 4.0 14.5 8.0 15.1 1.7 0.7 9.6 2.1 1.5 13.4 47.2 6.2 24.0 15.0 2.9 5.4 16.5 47.3 16.6 29.4 28.9 11.3 20.6 24.5 31.4 20.3 9.1 24.4 19.4 17.5 39.5 17.4 17.5 49.5 26.6 4.2 0.2 20.2 29.0 1.4 1.1 21.4 2.1 6.4 15.5 30.1 21.7 101.5 42.5 14.2 77.8 9.7 8.1 37.4 14.1 54.1 41.7 11.7 8.1 26.4 34.8 14.5 31.8 8.4 5.9 3.0 42.0 21.2 13.0 30.7 20.2 22.9 42.8 19.1 21.1 59.3 24.8 36.1 23.1 0.0 0.2 0.1 0.8 0.2 0.3 0.3 1.1 1.3 0.7 1.0 0.3 0.6 0.6 1.5 0.1 0.0 5.2 0.6 3.7 8.3 9.0 7.7 3.2 5.4 9.9 8.1 8.8 7.4 8.0 13.4 7.5 6.4 1.7 0.7 3.0 4.2 1.6 2.3 6.8 2.9 5.9 8.9 2.5 0.0 1.9 1.8 6.2 7.2 7.2 12.3 0.0 0.2 6.9 1.3 2.7 3.5 0.0 33.6 2.3 0.2 7.8 2.6 4.1 2.9 0.0 2.1 2.5 1.3 4.4 8.4 2.6 4.0 0.0 2.5 1.9 9.0 1.2 4.8 0.0 0.0 0.0 1.0 1.0 1.5 34.5 0.2 2.4 0.4 14.6 1.1 6.3 0.1 1.1 4.7 6.6 2.6 4.3 77.7 26.2 9.5 3.8 1.9 7.5 1.2 3.3 0.8 CCNF "FBX1, FBXO1" ENSG00000162063 "Cyclin F" P41002 16 2429394-2458854 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 37.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA060596, HPA070495, HPA071600" Enhanced Supported Centrosome NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "HPA060596: AB_2684329, HPA070495: AB_2686273, HPA071600: AB_2686424" "unprognostic (3.87e-2)" "unprognostic (2.21e-2)" "unprognostic (1.57e-3)" "unprognostic (3.70e-3)" "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (7.46e-7)" "unprognostic (2.45e-2)" "unprognostic (1.75e-2)" "unprognostic (1.99e-1)" "unprognostic (1.01e-2)" "unprognostic (1.58e-2)" "unprognostic (0.00e+0)" "unprognostic (1.22e-2)" "unprognostic (1.10e-2)" "unprognostic (4.25e-2)" "unprognostic (2.74e-1)" 1.4 1.0 2.5 3.8 2.1 7.3 1.9 2.9 2.7 1.3 0.0 2.0 2.8 0.8 2.0 4.0 0.8 0.8 0.6 2.4 2.0 0.6 0.7 1.0 7.4 1.5 2.0 1.0 0.8 0.5 0.8 2.5 1.3 1.6 2.0 0.8 2.1 1.1 1.3 4.8 2.1 1.1 0.8 2.2 1.6 2.7 2.6 15.1 0.7 1.3 9.6 1.7 1.5 1.7 21.0 32.4 31.3 28.9 2.2 2.9 23.8 24.1 12.2 34.2 26.1 64.6 25.6 42.3 8.0 14.1 10.2 33.1 52.2 19.6 16.4 30.9 23.4 46.1 35.3 20.4 2.3 30.4 30.7 2.0 2.5 24.1 11.7 4.4 25.5 36.5 52.0 28.5 17.6 45.6 46.1 25.0 31.2 22.6 13.2 76.2 35.1 39.5 9.5 9.3 29.8 17.0 36.0 32.8 6.4 15.6 34.3 16.6 18.1 19.1 46.7 13.5 27.1 16.4 20.9 74.5 5.6 31.8 26.9 0.0 0.3 0.0 0.7 0.1 0.4 0.6 0.4 0.9 0.1 0.4 0.3 0.4 0.0 1.3 0.3 0.5 0.5 0.6 2.5 2.1 2.9 2.7 2.4 2.0 1.5 2.0 1.3 0.8 2.6 1.7 0.9 0.0 3.9 3.3 2.7 2.8 2.7 1.4 6.2 5.3 2.4 2.0 1.9 0.0 1.6 1.8 12.5 7.0 3.7 2.4 0.0 1.2 0.9 1.0 2.7 2.2 1.2 37.5 5.7 0.6 12.2 2.2 5.6 1.0 1.3 8.9 2.5 0.9 6.1 8.4 5.6 2.6 4.1 2.4 1.6 0.0 1.8 1.5 5.4 0.0 0.8 0.9 2.1 1.0 1.0 1.1 0.3 2.6 7.2 1.9 0.9 0.2 0.3 1.6 0.0 0.8 2.7 3.9 5.7 3.5 1.1 1.9 3.4 1.7 4.7 1.6 CDC20 "CDC20A, p55CDC" ENSG00000117399 "Cell division cycle 20" Q12834 1 43358981-43363203 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 53.9;lymphoid tissue: 52.6;testis: 49.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 65.0;Early spermatids: 135.0;Erythroid cells: 96.0;Extravillous trophoblasts: 146.2;Spermatocytes: 126.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7 "memory B-cell: 4.2;memory CD4 T-cell: 3.2;memory CD8 T-cell: 3.5;NK-cell: 9.5;T-reg: 11.6" "Group enriched" "Detected in many" 9 "B-cells: 4.2;NK-cells: 9.5;T-cells: 11.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB004525, HPA045842, HPA055288" Enhanced Enhanced Nucleoplasm,Cytosol Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "CAB004525: AB_628089, HPA045842: AB_2679470, HPA055288: AB_2682773" "unprognostic (1.66e-2)" "unprognostic (1.09e-1)" "unprognostic (1.73e-2)" "unprognostic (2.14e-3)" "unprognostic (1.58e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (4.00e-8)" "unprognostic (9.06e-3)" "unprognostic (1.17e-2)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.32e-4)" "unprognostic (8.55e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.84e-2)" "unprognostic (2.28e-1)" "unprognostic (2.01e-1)" "unprognostic (1.29e-2)" 1.6 1.5 0.6 16.2 1.1 53.9 5.2 0.8 1.3 3.5 0.4 14.8 13.7 2.3 2.5 27.2 1.7 1.2 0.9 0.7 1.1 2.3 1.7 2.5 32.6 1.3 1.1 0.7 0.6 0.2 0.3 9.7 1.1 0.8 16.0 0.2 4.4 0.7 0.3 11.3 12.2 7.3 0.8 11.7 7.0 49.1 1.7 52.6 1.7 0.2 50.8 3.3 7.0 1.3 311.9 148.2 202.8 133.4 6.9 17.6 193.5 140.3 125.0 400.0 211.4 234.5 250.9 178.3 80.1 130.1 140.6 212.8 225.3 267.9 331.5 140.8 165.6 261.4 143.6 147.3 2.1 184.3 91.4 6.0 12.4 278.2 249.6 35.1 172.2 167.5 120.2 119.3 184.0 120.4 179.2 113.5 257.2 147.0 196.9 255.8 277.9 112.9 98.5 81.3 119.2 58.9 248.1 165.8 76.6 154.9 116.3 231.7 90.2 118.9 276.2 133.7 445.0 90.6 86.7 185.7 85.2 227.6 181.6 0.0 0.1 0.0 0.3 0.0 0.0 4.2 3.2 3.5 0.9 0.9 0.1 0.3 0.7 9.5 0.0 0.2 11.6 2.8 0.6 1.1 0.8 1.3 0.7 1.1 1.3 1.1 1.1 0.8 1.7 1.3 2.1 0.0 1.1 0.0 12.2 10.5 3.8 17.6 6.2 0.5 6.4 9.7 0.7 1.5 4.8 0.0 0.0 65.0 2.8 16.9 0.0 2.2 135.0 14.6 2.4 4.5 0.0 96.0 0.2 0.4 146.2 9.3 11.7 4.6 0.0 46.5 7.9 1.3 37.4 0.0 0.0 18.5 24.4 6.2 7.5 18.5 2.8 9.3 0.0 0.0 1.8 0.3 0.0 0.0 1.6 0.7 0.5 1.9 34.4 2.7 3.2 3.1 8.3 2.9 0.0 1.0 25.4 126.5 39.8 47.3 8.4 10.7 5.1 1.6 37.5 7.4 CDC25A ENSG00000164045 "Cell division cycle 25A" P30304 3 48157146-48188417 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.3;lymphoid tissue: 8.8;testis: 13.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 111.2;Early spermatids: 18.3;Late spermatids: 31.8;Spermatogonia: 16.3" "Cancer enhanced" "Detected in many" "testis cancer: 19.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005855, HPA008803" Approved "Nucleoplasm,Golgi apparatus" NA Yes "Cluster 43: B-cells - Humoral immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "Golgi apparatus" "HPA005855: AB_1846364, HPA008803: " "unprognostic (1.49e-1)" "unprognostic (8.13e-2)" "unprognostic (1.20e-2)" "unprognostic (1.43e-3)" "unprognostic (2.14e-1)" "unprognostic (9.51e-2)" "unprognostic (7.05e-7)" "unprognostic (1.35e-2)" "unprognostic (4.32e-3)" "unprognostic (8.92e-3)" "unprognostic (4.41e-2)" "unprognostic (9.09e-2)" "unprognostic (4.41e-3)" "unprognostic (1.57e-3)" "unprognostic (1.07e-1)" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" 0.7 0.9 0.8 3.3 0.8 15.3 1.1 0.7 1.0 0.6 0.7 3.5 2.0 0.6 0.9 2.4 0.2 0.3 0.4 0.8 2.0 0.7 0.8 0.3 4.4 1.1 1.9 2.2 0.7 0.8 0.8 2.6 1.7 0.6 3.9 2.0 0.8 0.6 0.4 0.6 1.8 1.1 0.8 2.0 0.9 13.3 2.0 8.8 1.8 0.3 5.6 0.9 0.9 0.7 22.2 10.7 50.0 27.2 1.7 3.2 34.2 29.9 11.3 36.7 29.6 46.8 11.2 64.9 11.4 8.0 23.4 16.3 86.6 20.6 38.6 21.4 45.1 83.8 19.0 23.1 1.7 59.4 23.4 1.7 3.1 45.8 19.6 4.6 14.1 47.8 67.6 33.6 20.1 11.8 74.8 46.6 73.4 20.2 24.2 33.2 32.9 35.1 9.5 20.7 23.5 28.8 18.6 21.6 9.5 31.7 11.3 41.9 7.2 18.0 27.7 20.3 41.4 16.7 54.2 101.5 13.5 65.2 15.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.7 1.0 0.8 2.0 1.1 1.9 1.7 0.8 2.0 0.7 0.3 0.0 0.0 1.0 1.1 0.4 0.4 0.8 1.8 0.5 1.2 1.0 111.2 0.0 0.1 0.0 2.1 4.2 0.2 2.4 0.0 0.4 18.3 0.5 0.9 2.7 1.2 8.0 0.2 0.9 7.4 1.5 1.5 1.3 0.0 4.6 1.4 0.3 3.1 0.0 0.5 2.0 0.0 0.6 0.9 31.8 1.5 0.5 0.0 0.0 0.1 1.1 0.0 0.5 0.0 1.1 0.8 1.9 13.0 0.7 0.4 0.4 0.2 0.4 0.0 0.1 2.2 14.5 16.3 4.3 0.0 0.3 0.6 2.4 4.1 0.5 CDC25B ENSG00000101224 "Cell division cycle 25B" P30305 20 3786772-3806121 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "B-cells: 7.2;NK-cells: 18.1;T-cells: 28.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038892, HPA038893, HPA075215" Enhanced Uncertain "Vesicles,Mitotic spindle" Yes Yes "Cluster 20: T-cells - T-cell receptor" "Cluster 64: Macrophages - Immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Mitotic spindle" "HPA038892: AB_2676258, HPA038893: AB_2676259, HPA075215: " "unprognostic (4.69e-2)" "unprognostic (5.74e-2)" "unprognostic (2.93e-2)" "prognostic unfavorable (4.76e-4)" "unprognostic (1.13e-1)" "unprognostic (4.23e-1)" "prognostic unfavorable (1.19e-4)" "unprognostic (1.31e-2)" "unprognostic (4.92e-2)" "unprognostic (2.74e-1)" "unprognostic (1.67e-1)" "unprognostic (6.03e-2)" "prognostic unfavorable (2.94e-13)" "unprognostic (1.15e-1)" "unprognostic (2.38e-1)" "unprognostic (3.94e-1)" "unprognostic (9.46e-2)" 29.2 15.6 30.5 28.8 32.4 29.4 25.1 39.2 33.2 41.7 23.2 37.6 14.4 35.0 9.4 27.1 31.5 17.9 16.3 27.6 32.5 31.3 24.8 78.4 47.6 31.3 29.9 37.4 12.8 3.8 45.7 31.1 30.2 25.4 11.3 7.8 16.7 8.9 10.5 21.8 41.2 14.2 27.4 56.1 30.1 12.4 30.9 44.7 41.8 6.3 32.8 35.8 30.2 35.8 129.6 273.2 36.5 60.0 43.8 43.0 19.3 63.3 95.3 103.1 75.9 49.2 182.9 91.3 27.5 65.4 253.5 183.5 50.6 105.8 50.2 36.2 54.4 49.4 88.5 59.6 178.4 38.6 25.0 41.1 85.0 95.4 115.7 35.6 58.4 44.2 33.3 232.7 63.1 105.5 119.0 57.7 27.3 90.9 116.9 62.0 102.6 67.5 73.2 12.2 25.8 56.9 148.6 140.8 78.1 31.7 48.1 20.4 48.6 55.1 66.2 101.5 85.0 57.8 97.8 36.8 28.1 38.0 54.6 3.9 2.4 0.0 22.7 3.4 21.3 5.8 22.6 23.3 2.4 7.2 18.6 21.6 0.3 18.1 1.7 1.3 28.2 11.2 30.5 32.4 39.2 33.2 27.6 32.5 31.3 29.9 30.2 27.4 30.9 35.8 14.0 9.6 21.7 18.6 21.7 11.2 6.0 10.9 7.4 14.4 4.8 5.5 8.6 8.6 4.5 7.3 2.1 11.9 30.6 5.8 0.0 9.9 0.7 2.7 20.6 27.1 7.8 32.6 39.2 4.8 17.7 15.7 17.3 5.4 1.3 11.5 14.3 13.7 30.4 3.3 38.0 10.4 12.2 14.8 9.4 1.1 7.2 12.4 17.8 6.5 8.8 8.3 44.3 22.6 13.2 15.0 4.3 9.1 49.6 6.0 5.5 11.1 3.7 2.6 0.0 26.5 14.0 2.3 12.3 10.3 11.2 3.6 36.4 7.1 10.9 4.4 CDC25C "CDC25, PPP1R60" ENSG00000158402 "Cell division cycle 25C" P30307 5 138285269-138338355 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.8;lymphoid tissue: 8.9;testis: 18.1" "Cell type enhanced" "Detected in many" "Early spermatids: 41.4;Late spermatids: 42.1;Spermatocytes: 53.6;Spermatogonia: 13.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB003800, HPA066991" Approved Enhanced "Nuclear speckles" No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" "CAB003800: AB_562081, HPA066991: AB_2685760" "unprognostic (2.45e-3)" "unprognostic (5.89e-3)" "prognostic favorable (2.49e-4)" "unprognostic (9.72e-3)" "unprognostic (2.17e-1)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.03e-6)" "prognostic unfavorable (4.38e-4)" "unprognostic (5.56e-2)" "unprognostic (2.08e-1)" "unprognostic (1.70e-3)" "unprognostic (1.00e-1)" "unprognostic (0.00e+0)" "unprognostic (5.04e-2)" "unprognostic (1.43e-1)" "unprognostic (2.59e-1)" "unprognostic (3.06e-1)" 0.2 0.2 0.2 2.1 0.2 5.8 0.7 0.3 0.3 0.3 0.2 3.4 3.0 0.4 0.2 1.4 0.2 0.2 0.1 0.2 0.2 0.1 0.5 0.3 3.2 0.2 0.3 0.0 0.4 0.1 0.1 1.2 0.2 0.2 4.1 0.1 0.3 0.1 0.0 1.4 3.0 0.8 0.1 0.9 1.1 18.1 0.2 8.9 0.1 0.0 4.6 0.5 0.5 0.2 27.9 11.0 38.4 28.9 0.9 3.6 9.9 16.4 17.5 36.2 50.3 27.3 52.8 13.3 13.8 10.1 40.5 14.9 31.7 25.9 34.9 11.1 21.5 9.6 15.0 21.2 0.3 6.3 10.0 0.8 0.9 22.0 18.0 3.8 24.6 28.9 14.8 24.2 22.9 15.5 19.3 16.7 9.7 22.3 12.2 11.9 34.2 15.0 6.4 8.4 19.2 11.9 36.8 11.0 16.9 32.6 18.7 13.9 7.2 19.9 16.8 13.9 26.5 15.0 13.4 13.0 8.3 14.3 15.6 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.6 0.1 0.2 0.2 0.3 0.3 0.2 0.2 0.2 0.3 0.2 0.1 0.2 0.2 0.1 0.0 0.0 1.3 0.9 0.6 0.3 1.1 1.8 0.0 0.9 0.8 0.3 0.0 0.2 0.0 0.0 5.0 0.5 1.8 0.0 0.1 41.4 0.4 0.9 0.6 0.0 9.5 1.3 0.0 6.9 1.1 3.6 1.2 0.0 5.5 1.4 0.4 2.7 0.0 1.0 3.9 2.0 0.6 0.5 42.1 1.8 1.2 0.0 1.0 0.6 0.0 0.0 1.0 0.3 0.0 1.4 0.4 4.5 0.3 0.9 0.1 0.1 0.0 0.0 0.2 0.9 53.6 13.0 4.3 0.4 1.4 0.6 0.2 4.9 0.6 CDC27 "ANAPC3, APC3, D0S1430E, D17S978E, NUC2" ENSG00000004897 "Cell division cycle 27" P30260 17 47117703-47189422 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 149.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016315, HPA028129, HPA052399, HPA065835" Supported Enhanced Nucleoplasm NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "CAB016315: AB_627228, HPA028129: AB_10603559, HPA052399: AB_2681814, HPA065835: " "unprognostic (2.34e-2)" "unprognostic (8.83e-3)" "prognostic favorable (1.77e-4)" "unprognostic (4.26e-2)" "unprognostic (7.99e-2)" "unprognostic (8.93e-3)" "prognostic unfavorable (4.38e-4)" "prognostic unfavorable (8.15e-4)" "unprognostic (1.98e-1)" "unprognostic (1.45e-1)" "unprognostic (4.05e-3)" "unprognostic (6.17e-2)" "prognostic unfavorable (6.39e-5)" "unprognostic (2.64e-1)" "unprognostic (1.58e-1)" "unprognostic (7.95e-2)" "unprognostic (3.66e-2)" 23.0 15.2 9.3 20.1 12.0 27.6 18.1 18.3 15.2 18.0 5.6 15.2 14.6 20.7 13.1 16.6 15.1 18.4 23.3 11.6 12.0 15.2 22.4 18.1 23.4 10.6 10.8 17.0 14.5 24.4 10.6 25.5 11.5 15.1 17.7 13.7 12.2 15.4 22.4 12.1 13.8 24.5 10.5 19.1 15.9 25.0 11.3 25.0 42.4 28.8 24.0 19.8 11.2 11.3 80.7 84.1 69.1 56.1 45.5 72.0 41.0 110.9 99.0 103.3 105.1 54.2 41.4 107.4 72.7 93.5 66.0 37.5 75.2 62.6 141.2 155.5 77.2 125.0 92.9 48.6 49.2 74.4 54.6 52.4 30.2 93.5 73.1 49.7 108.6 61.6 101.6 58.0 85.2 68.3 91.8 33.5 32.8 45.2 67.8 48.9 177.3 47.8 62.0 50.0 45.8 55.9 55.4 19.4 61.2 58.6 58.6 51.7 116.9 107.1 91.9 68.6 82.9 58.8 110.2 95.8 59.4 43.6 76.0 9.3 3.2 4.9 5.3 7.1 5.2 4.0 4.2 5.5 4.2 6.3 4.2 5.0 4.0 8.7 5.3 5.2 8.3 3.5 9.3 12.0 18.3 15.2 11.6 12.0 10.6 10.8 11.5 10.5 11.3 11.3 63.7 9.6 26.3 61.0 28.7 26.0 17.8 25.9 38.1 22.1 21.3 17.5 39.8 21.5 27.1 20.2 16.7 31.4 22.5 11.5 15.6 28.1 28.9 20.8 33.9 50.7 13.8 149.8 124.5 26.5 35.6 41.4 21.4 22.1 26.6 24.8 38.9 27.1 27.2 35.3 104.4 12.8 8.2 28.5 22.1 33.6 28.3 30.6 7.2 83.4 31.5 19.4 35.0 89.0 96.1 30.1 9.5 29.7 39.0 18.7 13.5 23.6 16.2 14.9 19.7 41.6 40.8 97.3 38.6 32.6 26.9 11.5 27.8 34.2 16.2 17.1 CDC45 "CDC45L, CDC45L2" ENSG00000093009 "Cell division cycle 45" O75419 22 19479457-19520612 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.4;lymphoid tissue: 20.4;testis: 23.4" "Cell type enhanced" "Detected in many" "Early spermatids: 120.5;Erythroid cells: 29.7;Spermatocytes: 72.3;Spermatogonia: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "K-562: 370.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000614, CAB009459" Enhanced Supported Nucleoplasm,Centrosome,Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Centrosome, Cytosol" "CAB009459: AB_2078507, HPA000614: AB_1078487" "unprognostic (5.56e-2)" "unprognostic (6.12e-3)" "unprognostic (1.17e-3)" "unprognostic (3.42e-3)" "unprognostic (3.57e-1)" "unprognostic (7.42e-2)" "prognostic unfavorable (6.95e-6)" "unprognostic (6.01e-3)" "unprognostic (1.85e-3)" "unprognostic (1.47e-2)" "prognostic unfavorable (8.94e-4)" "unprognostic (7.28e-2)" "unprognostic (0.00e+0)" "unprognostic (7.62e-3)" "unprognostic (2.02e-1)" "unprognostic (8.52e-2)" "unprognostic (1.10e-1)" 0.5 0.5 0.7 6.2 0.5 25.4 1.5 0.2 0.2 1.1 0.4 4.6 3.5 0.9 0.3 5.3 0.4 0.5 0.3 0.2 0.4 0.3 1.2 0.9 11.3 0.5 0.4 0.2 0.2 0.2 0.1 3.2 0.5 0.4 6.0 0.1 0.9 0.2 0.1 3.3 3.1 1.8 0.2 2.8 2.6 23.4 1.1 20.4 0.3 0.0 11.8 1.9 1.7 0.3 57.4 42.2 56.4 42.9 2.0 5.6 24.4 65.4 31.6 75.5 75.5 35.8 30.5 62.2 23.2 21.0 28.9 51.9 58.2 45.9 59.5 72.3 96.3 82.8 50.1 41.3 3.1 125.0 43.7 1.3 2.4 57.9 26.0 7.0 38.8 63.0 370.6 73.3 44.8 77.2 98.1 56.5 16.7 106.2 34.4 77.1 95.5 26.5 16.9 49.3 72.1 37.0 38.1 40.0 12.0 21.7 26.2 51.0 15.0 60.0 91.6 46.0 62.8 24.6 46.8 67.5 30.1 58.9 82.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.3 0.7 0.1 0.0 0.2 0.1 0.5 0.5 0.1 0.3 0.9 0.6 0.7 0.5 0.2 0.2 0.2 0.4 0.5 0.4 0.5 0.2 1.1 0.3 0.2 0.0 0.0 0.0 1.9 2.7 1.7 3.7 0.0 0.0 0.7 0.8 0.4 0.0 0.5 0.0 0.0 11.9 1.4 1.9 0.0 0.8 120.5 0.9 0.7 1.2 0.0 29.7 0.1 0.0 19.8 2.3 1.5 1.0 0.0 5.5 3.6 0.0 7.2 0.0 0.1 1.2 4.1 0.6 1.0 14.4 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.7 12.6 0.2 0.4 0.0 0.3 0.0 6.6 1.5 13.9 72.3 50.7 3.3 1.8 4.9 1.2 0.8 5.1 2.5 CDC6 CDC18L ENSG00000094804 "Cell division cycle 6" Q99741 17 40287879-40304657 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.2;lymphoid tissue: 17.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 23.2;Erythroid cells: 37.2;Extravillous trophoblasts: 34.6;Plasma cells: 31.6;Spermatocytes: 69.5;Spermatogonia: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.6" "Group enriched" "Detected in many" 6 "dendritic cells: 3.6;NK-cells: 1.5;T-cells: 2.4" "Cell line enhanced" "Detected in all" "SK-BR-3: 500.3" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA050114, HPA065070" Approved Approved "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "Cytokinetic bridge, Mitotic spindle" "HPA050114: AB_2681021, HPA065070: AB_2732729" "unprognostic (1.29e-1)" "unprognostic (7.22e-2)" "unprognostic (1.23e-3)" "unprognostic (7.97e-2)" "unprognostic (7.12e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (5.96e-8)" "unprognostic (2.31e-3)" "unprognostic (1.46e-3)" "unprognostic (1.41e-1)" "prognostic unfavorable (2.90e-4)" "unprognostic (5.47e-2)" "unprognostic (3.00e-15)" "unprognostic (1.86e-2)" "unprognostic (1.35e-1)" "unprognostic (3.95e-3)" "unprognostic (3.88e-2)" 2.1 1.9 0.5 13.7 0.8 27.2 3.4 0.2 1.9 3.2 0.0 8.4 7.5 2.2 1.1 5.7 1.0 2.8 0.6 1.1 0.1 0.5 3.0 1.4 16.4 0.1 0.0 0.9 1.9 0.8 0.5 9.3 0.3 1.1 8.7 0.5 1.3 1.2 0.3 2.8 6.7 3.7 0.0 3.7 3.6 10.1 0.2 16.7 1.7 0.5 17.1 4.3 1.8 0.6 155.1 119.0 115.1 86.5 6.7 12.7 118.0 159.9 49.0 149.2 166.5 135.8 64.9 123.9 99.6 35.9 85.9 214.0 112.2 76.2 148.9 64.5 98.4 96.2 122.3 134.6 4.4 133.3 55.1 4.7 8.1 156.4 107.1 14.8 46.9 84.2 183.0 109.0 71.9 95.8 199.3 43.3 101.6 96.9 48.7 145.0 286.8 119.9 30.3 184.8 85.6 76.9 146.9 500.3 55.4 100.3 100.8 120.0 34.7 95.5 146.3 170.8 196.1 46.1 103.6 222.8 84.6 93.9 109.2 0.1 0.1 0.0 0.8 0.0 0.5 0.4 0.6 1.1 0.7 0.3 0.4 1.1 0.1 1.5 0.0 3.6 2.4 0.6 0.5 0.8 0.2 1.9 1.1 0.1 0.1 0.0 0.3 0.0 0.2 0.6 2.2 0.0 2.0 0.7 4.9 4.2 1.1 3.7 3.4 0.2 2.1 2.2 0.9 1.5 1.3 0.0 0.0 23.2 2.3 7.8 0.0 1.3 2.2 1.3 2.9 2.1 0.0 37.2 2.0 0.6 34.6 5.6 3.6 5.1 0.0 8.1 1.1 0.9 8.3 0.0 0.7 6.1 0.0 1.3 2.1 1.0 2.8 1.5 0.0 0.0 0.0 0.4 2.1 0.0 0.2 1.5 3.0 0.7 31.6 1.3 0.8 0.2 0.2 0.3 13.1 0.6 4.6 69.5 57.2 9.1 1.6 16.7 3.3 1.9 9.3 2.4 CDCA2 "PPP1R81, Repo-Man" ENSG00000184661 "Cell division cycle associated 2" Q69YH5 8 25459199-25507911 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 6.5;lymphoid tissue: 11.4;testis: 19.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 23.3;Early spermatids: 49.9;Erythroid cells: 19.0;Late spermatids: 24.2;Spermatocytes: 66.6;Spermatogonia: 27.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA026293, HPA030049" Enhanced Supported Nucleoplasm Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA026293: AB_1846384, HPA030049: AB_10600862" "unprognostic (2.12e-1)" "unprognostic (4.75e-3)" "prognostic favorable (9.62e-4)" "unprognostic (2.92e-2)" "unprognostic (9.69e-2)" "unprognostic (3.56e-2)" "unprognostic (2.50e-5)" "unprognostic (1.47e-3)" "unprognostic (6.06e-2)" "unprognostic (2.91e-3)" "unprognostic (1.32e-3)" "unprognostic (1.99e-1)" "prognostic unfavorable (2.30e-14)" "unprognostic (1.36e-2)" "unprognostic (4.02e-1)" "unprognostic (1.91e-1)" "unprognostic (5.30e-2)" 0.2 0.0 0.0 2.6 0.0 6.5 0.6 0.1 0.0 0.2 0.1 1.9 1.6 0.3 0.0 1.4 0.1 0.3 0.3 0.0 0.1 0.0 0.1 0.2 5.3 0.2 0.2 0.0 0.0 0.0 0.0 1.2 0.2 0.1 2.2 0.1 0.2 0.0 0.0 1.1 1.8 0.8 0.0 0.8 0.9 19.4 0.3 11.4 0.1 0.1 6.7 0.6 0.3 0.1 36.5 30.2 29.4 24.2 2.3 4.5 20.2 37.7 22.6 32.9 32.4 25.7 15.8 42.6 16.0 16.2 34.6 31.6 42.9 20.0 48.5 16.2 12.0 43.2 22.4 15.2 0.6 18.4 19.4 2.5 1.0 23.5 15.8 3.3 24.5 24.5 33.6 45.8 30.6 13.9 54.5 8.7 31.0 24.1 14.5 26.3 33.4 15.2 9.2 18.7 12.0 13.3 33.3 16.1 14.3 14.7 17.4 9.4 16.6 23.9 39.3 44.7 35.6 7.1 16.5 44.4 17.7 24.3 40.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.2 0.0 0.3 0.1 0.2 0.0 1.1 0.0 2.7 1.1 0.5 1.7 0.0 0.7 0.9 0.8 23.3 0.0 0.2 0.0 0.0 7.2 0.5 1.8 0.0 0.2 49.9 0.8 1.2 1.1 0.0 19.0 0.2 0.0 13.4 2.5 4.1 1.4 0.0 8.8 1.1 0.1 4.1 0.0 0.1 1.3 0.0 2.9 0.6 24.2 1.2 2.1 0.0 0.0 0.6 0.1 2.1 0.5 0.6 0.2 0.1 0.0 15.8 0.5 0.5 1.2 0.9 0.5 13.1 0.1 2.1 66.6 27.8 10.7 0.9 1.6 2.9 1.3 3.6 0.5 CDCA3 "GRCC8, TOME-1" ENSG00000111665 "Cell division cycle associated 3" Q99618 12 6844793-6851292 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.5;retina: 66.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 56.3;Erythroid cells: 46.5;Extravillous trophoblasts: 74.1;Proximal enterocytes: 65.5;Spermatocytes: 71.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "T-reg: 4.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA026587 Approved Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA026587: AB_1846386" "unprognostic (3.05e-1)" "unprognostic (1.32e-1)" "unprognostic (9.85e-2)" "unprognostic (1.63e-2)" "unprognostic (2.42e-1)" "unprognostic (7.41e-2)" "prognostic unfavorable (6.51e-5)" "prognostic unfavorable (9.77e-5)" "unprognostic (3.88e-2)" "unprognostic (1.27e-1)" "unprognostic (1.80e-3)" "unprognostic (8.81e-2)" "unprognostic (0.00e+0)" "unprognostic (1.22e-1)" "unprognostic (1.09e-1)" "unprognostic (2.11e-1)" "unprognostic (4.94e-2)" 1.2 2.6 0.7 7.3 0.5 16.0 1.2 1.0 1.0 4.4 0.3 6.1 20.7 2.9 0.4 9.0 1.9 1.1 2.8 0.6 0.6 1.6 1.6 1.7 17.2 0.7 0.7 4.6 1.1 0.4 8.6 4.7 0.6 3.1 7.8 66.3 2.5 0.3 0.5 6.3 18.5 3.0 0.4 4.6 3.2 21.4 0.6 30.5 1.8 0.2 23.4 2.2 4.0 0.5 106.8 88.8 81.0 45.1 4.3 6.8 95.0 71.7 46.4 119.5 83.3 142.7 86.9 64.9 8.6 54.9 86.9 71.0 53.3 55.0 117.0 97.2 60.9 56.8 58.9 81.7 0.5 41.3 47.2 3.1 3.9 63.0 34.6 27.9 50.9 44.2 47.8 36.4 116.7 94.1 60.0 46.0 86.2 75.8 62.3 57.6 68.5 34.3 40.2 36.4 12.2 23.6 61.8 53.5 18.7 87.0 21.9 38.6 22.3 52.6 67.2 35.0 117.2 19.7 21.5 104.2 25.4 53.6 92.0 0.0 0.2 0.0 0.1 0.1 0.3 0.7 0.7 0.8 0.2 0.2 0.2 0.4 0.2 0.4 0.3 1.1 4.3 0.5 0.7 0.5 1.0 1.0 0.6 0.6 0.7 0.7 0.6 0.4 0.6 0.5 0.7 0.0 0.5 0.7 4.1 2.9 1.7 5.0 2.2 12.3 1.9 2.5 1.2 1.5 1.1 0.0 56.3 29.5 0.9 6.9 0.0 1.1 12.4 1.8 2.3 1.7 1.2 46.5 0.5 0.4 74.1 5.2 4.6 2.3 4.5 15.2 3.9 1.6 19.3 6.7 0.6 11.9 4.1 4.0 3.1 6.8 1.8 3.5 0.0 1.0 1.1 1.1 1.0 0.5 0.5 0.4 4.0 0.4 19.2 1.4 65.5 0.9 0.4 18.0 6.6 0.5 8.3 71.5 14.8 12.6 1.8 8.5 4.6 1.4 17.4 2.6 CDCA4 "FLJ20764, Hepp" ENSG00000170779 "Cell division cycle associated 4" Q9BXL8 14 105009573-105021083 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 55.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 64.2;Cytotrophoblasts: 84.5;Extravillous trophoblasts: 154.5;Spermatogonia: 69.9;Suprabasal keratinocytes: 67.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA064971 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Plasma membrane, Cytosol" "HPA064971: AB_2685395" "unprognostic (2.22e-3)" "unprognostic (1.84e-1)" "unprognostic (2.69e-1)" "unprognostic (9.93e-3)" "unprognostic (1.42e-1)" "unprognostic (8.36e-2)" "prognostic unfavorable (4.19e-4)" "prognostic unfavorable (7.94e-4)" "unprognostic (4.20e-2)" "unprognostic (8.54e-2)" "prognostic unfavorable (6.67e-4)" "unprognostic (6.73e-2)" "prognostic unfavorable (1.47e-6)" "unprognostic (2.15e-1)" "unprognostic (1.55e-1)" "unprognostic (7.50e-2)" "unprognostic (1.24e-2)" 3.9 2.6 1.9 7.4 2.0 55.8 4.2 3.0 2.1 8.7 2.1 4.6 4.7 5.4 1.8 18.6 4.1 2.6 2.7 1.7 1.8 3.4 2.7 3.6 11.6 2.1 1.9 4.1 3.2 1.8 1.7 9.2 2.1 3.8 2.9 1.3 5.5 2.2 1.4 24.7 4.9 3.5 1.9 6.6 3.8 11.6 2.0 14.6 3.3 1.5 8.5 4.2 10.2 2.0 40.6 41.3 46.7 35.6 7.9 13.2 61.1 59.0 18.0 45.2 39.7 50.9 50.2 52.9 31.5 20.9 34.5 63.5 32.9 68.0 27.1 58.2 26.1 33.4 33.9 43.2 9.7 59.8 27.0 9.4 20.8 35.2 32.7 15.1 31.4 45.0 37.5 53.0 32.1 98.8 56.2 40.1 34.8 35.1 94.0 53.6 68.1 19.7 15.9 46.2 27.2 33.5 56.6 22.3 46.8 20.5 44.0 39.8 48.8 39.9 50.5 55.3 79.5 19.5 25.9 54.4 33.5 30.2 67.5 1.1 4.3 10.6 11.9 4.9 14.8 8.4 12.7 16.7 4.7 5.4 7.4 8.9 1.6 12.9 5.6 5.1 11.1 7.0 1.9 2.0 3.0 2.1 1.7 1.8 2.1 1.9 2.1 1.9 2.0 2.0 5.4 0.0 2.2 0.7 7.4 64.2 26.5 36.6 13.1 3.4 8.7 8.3 0.6 0.0 9.0 1.8 0.0 84.5 11.5 4.3 3.9 12.7 8.1 9.0 9.0 10.9 3.0 53.0 1.8 7.0 154.5 10.2 3.1 12.5 28.6 15.1 7.9 2.2 24.3 13.5 1.3 6.6 6.1 5.9 22.6 6.8 8.4 8.4 17.8 2.8 9.3 4.6 9.2 1.0 1.8 12.3 3.3 6.0 11.8 16.1 1.9 1.8 7.7 2.6 6.6 4.6 12.5 43.0 69.9 21.3 67.1 25.9 17.7 3.6 9.5 43.2 CDCA5 ENSG00000146670 "Cell division cycle associated 5" Q96FF9 11 65066300-65084164 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 53.4;lymphoid tissue: 27.6;testis: 37.8" "Cell type enhanced" "Detected in many" "Early spermatids: 56.5;Extravillous trophoblasts: 38.3;Late spermatids: 116.9;Spermatocytes: 50.4;Spermatogonia: 31.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "NK-cell: 2.8;T-reg: 2.0" "Group enriched" "Detected in many" 5 "NK-cells: 2.8;T-cells: 2.0" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in single" "white matter: 1.4" "Low region specificity" "Detected in many" "HPA023691, HPA076007" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA023691: AB_1846392, HPA076007: " "unprognostic (3.14e-2)" "unprognostic (4.20e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.67e-4)" "unprognostic (2.15e-1)" "unprognostic (2.68e-1)" "prognostic unfavorable (8.21e-6)" "unprognostic (1.41e-3)" "unprognostic (7.55e-3)" "unprognostic (6.93e-2)" "prognostic unfavorable (8.72e-6)" "unprognostic (2.16e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.55e-3)" "unprognostic (1.86e-1)" "unprognostic (1.35e-1)" "unprognostic (8.97e-2)" 1.4 1.2 1.3 10.5 1.3 53.4 2.0 0.8 1.8 1.9 0.9 6.8 5.8 1.3 0.3 9.3 0.9 0.9 0.9 1.5 0.9 0.9 1.3 1.9 17.0 1.6 1.3 0.6 0.7 0.4 0.5 6.5 1.6 0.8 7.7 0.5 1.4 0.5 0.6 4.2 5.8 3.1 0.8 6.6 3.1 37.8 1.8 27.6 0.6 0.4 16.2 2.2 2.8 1.3 131.7 74.9 67.2 57.3 4.5 7.3 57.8 92.7 37.4 103.6 81.5 77.7 75.4 121.3 52.3 29.4 120.8 87.9 110.3 49.5 98.6 122.0 52.2 107.7 54.4 64.1 0.4 116.8 81.8 2.5 4.5 96.3 44.0 10.8 32.6 138.4 126.6 206.6 63.5 109.2 164.7 116.9 107.8 63.0 92.4 140.4 76.8 111.9 21.2 49.6 89.1 68.4 59.3 80.7 62.8 41.6 104.7 54.7 19.9 92.7 97.2 99.5 101.7 106.9 187.8 195.4 37.2 69.5 97.4 0.0 0.1 0.2 0.4 0.0 0.0 0.3 0.5 0.3 0.4 0.5 0.0 0.3 0.0 2.8 0.3 0.3 2.0 0.7 1.3 1.3 0.8 1.8 1.5 0.9 1.6 1.3 1.6 0.8 1.8 1.3 0.9 0.0 0.5 0.0 4.6 3.8 1.2 1.3 0.6 0.6 2.3 4.4 1.0 0.0 0.8 0.0 2.1 19.7 2.2 4.6 1.9 0.8 56.5 1.1 1.5 2.3 0.0 21.8 1.1 0.8 38.3 3.5 3.1 1.5 3.8 14.5 1.1 0.0 11.7 1.7 0.6 4.7 2.0 2.8 1.5 116.9 2.8 1.7 0.0 1.0 2.1 0.9 2.1 0.0 0.6 0.6 0.1 1.5 16.2 1.1 1.1 0.6 0.4 0.2 0.0 0.5 2.7 50.4 31.1 7.1 1.0 3.7 4.2 1.9 9.4 1.6 CDCA7 "FLJ14736, JPO1" ENSG00000144354 "Cell division cycle associated 7" Q9BWT1 2 173354820-173368997 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.4;lymphoid tissue: 50.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 45.7;Intestinal goblet cells: 40.7;Leydig cells: 53.7;Undifferentiated cells: 124.2" "Cancer enhanced" "Detected in all" "colorectal cancer: 43.3" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "T-reg: 7.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MOLT-4: 279.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005565 Supported Nucleoplasm,Cytosol No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "HPA005565: AB_2078680" "unprognostic (1.67e-3)" "unprognostic (2.26e-1)" "unprognostic (1.21e-1)" "unprognostic (1.54e-2)" "unprognostic (2.16e-1)" "unprognostic (1.44e-2)" "prognostic unfavorable (4.20e-4)" "unprognostic (7.54e-2)" "prognostic unfavorable (5.50e-4)" "unprognostic (4.96e-2)" "unprognostic (2.83e-1)" "unprognostic (8.97e-3)" "unprognostic (0.00e+0)" "unprognostic (4.53e-3)" "unprognostic (1.96e-1)" "unprognostic (2.04e-1)" "unprognostic (2.47e-2)" 1.7 0.3 0.7 13.1 0.6 23.0 2.4 0.5 0.7 12.6 6.5 25.5 30.7 13.8 3.3 10.1 3.8 1.5 0.8 0.7 1.2 0.5 0.3 1.6 37.5 0.7 0.9 1.1 1.7 0.3 0.1 7.4 0.7 3.0 29.5 0.4 2.5 1.2 3.1 11.7 32.4 3.4 0.7 2.4 14.3 6.0 1.2 50.1 0.5 0.8 41.2 2.8 6.7 1.0 44.2 33.3 76.4 83.3 3.6 14.0 79.9 26.0 9.2 60.3 67.2 51.6 54.4 122.1 32.2 15.8 23.5 45.0 122.4 46.6 87.0 59.2 67.4 27.6 24.6 66.0 3.8 181.2 25.1 11.4 3.9 32.8 27.3 7.8 28.0 158.1 67.4 27.2 17.7 35.4 279.7 181.7 90.4 103.4 22.7 194.4 58.2 77.3 29.5 38.2 22.3 39.2 40.8 13.4 22.0 67.9 0.3 70.5 13.0 39.3 16.8 12.9 48.5 7.4 17.1 173.0 24.4 99.8 34.0 0.0 0.5 0.0 1.1 0.0 0.4 1.9 3.0 5.9 3.5 0.3 0.2 1.0 0.2 3.2 0.0 0.5 7.9 2.3 0.7 0.6 0.5 0.7 0.7 1.2 0.7 0.9 0.7 0.7 1.2 1.0 1.0 0.0 0.6 0.7 3.0 20.3 14.9 3.3 14.8 0.0 2.6 6.5 1.1 0.0 0.3 0.0 0.0 45.7 1.6 17.1 0.0 0.2 0.9 3.2 33.0 3.4 12.2 33.6 0.1 0.2 29.9 4.1 22.4 6.8 0.0 18.5 0.0 0.2 10.4 0.0 10.5 40.7 4.1 1.0 4.4 2.2 53.7 2.3 3.6 0.0 1.2 0.7 0.0 0.5 0.1 1.0 11.1 34.6 3.8 5.3 11.9 0.0 0.1 0.0 0.0 1.1 7.2 13.8 28.9 21.8 15.9 10.1 9.1 2.7 124.2 3.8 CDCA7L "JPO2, R1, RAM2" ENSG00000164649 "Cell division cycle associated 7 like" Q96GN5 7 21900899-21945903 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 51.0;Spermatogonia: 63.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 101.0;naive B-cell: 124.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 4 "olfactory bulb: 10.1" "HPA027169, HPA074623" Approved Supported Nucleoplasm,Nucleoli,Cytosol No Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Nucleoli" Cytosol "HPA027169: AB_1856058, HPA074623: " "unprognostic (5.13e-3)" "unprognostic (5.94e-2)" "unprognostic (1.91e-1)" "unprognostic (4.63e-2)" "unprognostic (2.33e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (4.36e-6)" "unprognostic (4.09e-2)" "unprognostic (2.86e-1)" "unprognostic (3.87e-2)" "unprognostic (3.22e-2)" "unprognostic (2.34e-1)" "prognostic unfavorable (1.98e-4)" "unprognostic (2.00e-1)" "unprognostic (1.60e-1)" "unprognostic (1.73e-1)" "unprognostic (2.83e-3)" 5.9 1.4 3.9 15.0 9.1 51.7 15.7 5.7 5.2 8.7 17.8 17.0 10.7 13.8 5.5 11.2 11.5 8.1 25.3 3.9 3.5 2.8 4.8 14.0 37.1 6.9 4.8 21.8 13.0 1.8 1.1 4.7 3.8 7.3 19.0 5.1 9.0 7.6 6.2 18.5 13.6 11.9 5.0 13.3 17.8 18.5 7.8 49.0 29.8 3.4 31.8 6.3 8.1 9.8 84.5 27.6 26.0 0.6 14.5 17.9 0.0 65.9 58.2 51.8 73.5 11.3 75.4 173.6 21.8 59.3 102.4 51.1 41.4 69.4 103.6 0.3 28.6 42.3 83.8 7.4 21.1 111.1 0.4 35.2 12.7 40.0 116.9 54.9 104.8 133.5 58.3 0.1 41.4 34.5 146.1 46.1 153.2 17.4 36.2 141.0 94.0 119.8 15.4 14.8 96.9 79.7 30.3 19.9 29.9 34.4 45.6 54.6 43.0 57.1 68.5 101.3 83.8 90.6 63.6 223.0 55.7 154.6 54.5 1.1 2.3 43.2 2.2 3.8 0.3 101.0 6.4 3.2 14.9 124.5 30.9 12.8 3.8 3.4 4.9 75.9 9.9 12.2 3.9 9.1 5.7 5.2 3.9 3.5 6.9 4.8 3.8 5.0 7.8 9.8 1.0 19.2 31.5 7.5 51.0 27.1 23.7 6.9 17.1 1.5 12.5 20.7 38.7 11.5 19.0 0.0 2.1 0.5 30.7 8.4 3.9 8.9 7.3 5.4 2.7 4.8 10.7 21.9 0.5 6.2 0.3 13.4 18.3 5.3 8.8 14.9 1.4 4.0 10.8 13.5 1.0 26.1 8.2 15.2 3.5 5.2 4.1 7.0 8.8 1.9 1.6 2.4 1.0 15.1 8.7 3.9 7.4 2.6 20.2 14.2 1.5 0.1 4.2 2.7 13.1 6.8 12.4 4.6 63.5 9.6 7.7 0.3 5.4 8.3 23.0 6.2 CDCA8 "BOR, DasraB, FLJ12042, MESRGP" ENSG00000134690 "Cell division cycle associated 8" Q53HL2 1 37692481-37709719 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.5;lymphoid tissue: 38.8;testis: 22.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 34.1;Extravillous trophoblasts: 26.0;Spermatocytes: 76.8;Spermatogonia: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA028120, HPA028258, HPA028783, CAB040294" Enhanced Supported "Nucleoplasm,Nucleoli,Cytokinetic bridge" Yes Yes "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoli "Nucleoplasm, Cytokinetic bridge" "CAB040294: , HPA028120: AB_10670556, HPA028258: AB_10669864, HPA028783: AB_10671092" "unprognostic (8.36e-2)" "unprognostic (2.00e-1)" "unprognostic (8.39e-2)" "unprognostic (7.75e-3)" "unprognostic (2.34e-1)" "unprognostic (5.42e-2)" "prognostic unfavorable (4.93e-10)" "unprognostic (4.30e-3)" "prognostic unfavorable (6.04e-4)" "unprognostic (3.00e-1)" "prognostic unfavorable (8.32e-4)" "unprognostic (3.78e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (6.39e-3)" "unprognostic (2.99e-1)" "unprognostic (3.18e-1)" "unprognostic (1.67e-1)" 1.0 1.1 0.7 7.9 1.0 33.5 2.0 0.2 0.9 1.7 0.0 9.4 8.3 1.3 1.8 9.2 1.0 1.1 0.6 0.5 0.4 0.8 1.3 1.5 19.5 0.6 0.4 0.6 0.8 0.5 0.6 4.4 0.5 0.7 11.3 1.9 1.8 0.5 0.3 6.3 7.3 2.8 0.3 4.9 4.9 22.5 0.6 38.8 0.6 0.5 22.7 2.0 2.9 0.7 108.5 45.5 84.4 62.1 3.6 7.0 57.2 79.6 39.5 137.2 96.6 71.9 78.8 130.2 31.5 50.5 54.5 59.4 97.8 52.4 141.9 86.8 44.9 116.8 49.2 57.3 0.8 113.8 58.4 2.8 3.8 77.1 67.3 15.3 60.9 91.1 100.7 135.6 99.1 47.7 106.1 68.9 98.8 61.7 62.8 102.2 115.6 74.4 31.0 43.8 75.4 33.3 87.5 40.6 52.4 71.7 60.1 42.4 37.3 67.8 70.6 39.2 126.0 91.4 128.1 176.3 31.6 104.7 79.6 0.0 0.7 1.3 1.5 1.6 2.8 1.7 3.6 2.2 0.7 1.4 1.1 2.3 3.0 4.1 3.9 1.2 5.9 1.7 0.7 1.0 0.2 0.9 0.5 0.4 0.6 0.4 0.5 0.3 0.6 0.7 0.8 0.0 0.5 1.3 4.8 3.3 0.8 2.4 1.8 1.3 1.9 1.5 0.7 2.8 0.4 0.0 0.0 17.1 1.9 12.4 0.0 1.2 1.0 1.7 1.6 1.9 3.6 34.1 1.2 0.6 26.0 2.9 6.6 2.5 0.0 12.0 3.6 1.0 11.6 1.7 0.9 8.2 2.0 3.5 1.9 2.8 1.5 3.7 1.8 0.0 1.6 0.1 2.1 0.5 0.9 2.4 4.0 1.2 15.8 1.3 1.9 0.6 4.7 1.0 19.7 0.2 6.3 76.8 42.0 17.1 2.7 2.9 5.5 1.2 13.2 1.2 CDH11 "CAD11, OB" ENSG00000140937 "Cadherin 11" P55287 16 64943753-65126112 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 178.2;placenta: 122.2" "Cell type enhanced" "Detected in many" "Astrocytes: 93.0;Endometrial stromal cells: 125.0;Excitatory neurons: 122.2;Fibroblasts: 102.2;Microglial cells: 145.2;Oligodendrocyte precursor cells: 158.3;Oligodendrocytes: 106.3;Theca cells: 160.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 246.5;BJ hTERT+: 139.3;fHDF/TERT166: 332.3;HSkMC: 217.4;PC-3: 291.2;U-2197: 194.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013072 Enhanced NA Yes 4800000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB013072: AB_2533068" "unprognostic (1.77e-1)" "unprognostic (1.51e-1)" "unprognostic (1.50e-1)" "unprognostic (6.93e-2)" "unprognostic (6.00e-2)" "unprognostic (1.02e-1)" "unprognostic (6.96e-2)" "unprognostic (1.28e-1)" "unprognostic (2.09e-1)" "unprognostic (2.30e-2)" "unprognostic (3.74e-2)" "unprognostic (6.75e-2)" "prognostic unfavorable (2.48e-9)" "unprognostic (1.43e-3)" "unprognostic (3.20e-2)" "unprognostic (1.26e-1)" "unprognostic (5.07e-3)" 15.1 8.6 12.4 25.7 27.9 0.3 10.7 10.8 15.8 57.7 13.8 11.4 7.0 52.8 9.5 7.4 12.5 58.6 10.2 19.2 21.4 10.2 1.8 45.6 17.5 17.1 24.1 178.2 3.4 2.6 10.4 122.2 17.3 20.0 12.2 14.0 12.7 24.3 2.6 10.9 8.9 54.3 21.1 89.3 11.8 8.0 19.3 3.7 8.1 3.1 13.0 47.6 13.6 21.4 0.2 0.0 51.4 0.1 35.7 77.5 0.3 246.5 139.3 61.0 34.5 4.6 0.2 0.0 0.0 332.3 0.0 0.1 0.1 1.7 43.4 0.0 2.1 0.0 1.4 0.0 29.7 0.0 14.4 217.4 0.1 74.7 14.9 0.0 17.4 0.0 0.0 0.0 33.1 0.3 0.1 0.3 19.2 37.4 291.2 0.8 38.0 0.0 0.0 0.0 0.8 36.0 0.1 0.3 0.2 64.5 0.3 0.1 0.0 124.4 17.2 194.0 70.1 0.0 0.0 0.1 21.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 27.9 10.8 15.8 19.2 21.4 17.1 24.1 17.3 21.1 19.3 21.4 11.4 3.2 0.0 93.0 0.1 3.8 1.0 7.9 0.0 19.9 1.0 7.4 3.1 1.5 3.3 0.0 0.0 2.6 0.2 0.1 0.0 0.1 2.7 3.9 125.0 17.8 0.0 2.7 122.2 0.0 2.3 102.2 0.5 2.7 0.0 60.0 68.9 0.0 4.7 0.0 67.6 0.6 0.0 0.6 6.9 4.2 52.5 0.9 5.4 145.2 0.0 41.9 0.0 158.3 106.3 0.8 0.0 77.5 0.0 1.6 0.0 1.4 0.4 2.1 26.3 12.8 38.0 1.7 1.1 0.5 3.1 5.6 1.1 160.2 0.3 0.5 CDH18 "CDH14, EY-CADHERIN" ENSG00000145526 "Cadherin 18" Q13634 5 19471296-20575873 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 35.9" "Group enriched" "Detected in some" 5 "Excitatory neurons: 923.8;Inhibitory neurons: 694.3;Oligodendrocyte precursor cells: 248.3" "Cancer enhanced" "Detected in some" "ovarian cancer: 0.7" "Region enhanced" "Detected in many" "cerebellum: 35.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 4.4;GAMG: 7.6;hTERT-RPE1: 4.2;U-2 OS: 6.8;U-2197: 6.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014416 Uncertain "Intracellular and membrane" NA Yes "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA014416: AB_2668996" "unprognostic (1.57e-1)" "unprognostic (1.68e-1)" "unprognostic (5.26e-7)" "unprognostic (6.36e-2)" "unprognostic (1.10e-1)" "unprognostic (1.44e-2)" "unprognostic (1.20e-1)" "unprognostic (8.78e-2)" "unprognostic (3.30e-2)" "unprognostic (1.51e-2)" "unprognostic (8.69e-2)" "unprognostic (1.76e-2)" 0.0 4.6 2.7 0.0 6.8 0.0 0.0 35.9 12.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 8.4 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.9 4.0 0.0 5.7 0.0 0.0 2.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 1.8 1.9 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.2 0.0 0.3 0.0 0.6 2.9 2.5 0.1 1.6 0.1 0.5 0.0 0.0 0.0 4.4 0.0 7.6 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 1.7 4.2 0.0 0.0 0.1 0.5 0.3 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.9 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 6.8 6.2 0.0 1.7 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 6.8 35.9 12.3 6.1 8.4 0.0 0.4 5.7 0.0 1.9 1.9 0.0 0.0 0.0 22.9 0.0 0.0 1.3 0.0 0.0 6.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 109.9 0.0 0.0 0.0 0.0 0.0 923.8 0.0 5.3 0.3 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.0 694.3 0.0 0.0 0.0 0.0 19.2 0.3 0.1 0.0 17.8 0.0 0.2 0.0 248.3 15.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.0 1.6 0.0 0.1 0.1 6.4 3.4 0.0 0.0 0.3 0.0 0.3 0.0 0.0 CDK1 "CDC2, CDC28A" ENSG00000170312 "Cyclin dependent kinase 1" P06493 10 60778331-60794852 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Biological rhythms, Cell cycle, Cell division, Host-virus interaction, Mitosis" "Host cell receptor for virus entry, Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 53.2;lymphoid tissue: 74.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 80.9;Erythroid cells: 209.6;Extravillous trophoblasts: 144.6;Spermatocytes: 110.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "NK-cell: 3.2;T-reg: 3.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003387, CAB003799, CAB079974" Enhanced Supported Nucleoplasm,Cytosol NA Yes 51000 "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "CAB003799: AB_344898, CAB079974: , HPA003387: AB_1846356" "unprognostic (6.34e-2)" "prognostic favorable (8.81e-4)" "unprognostic (1.90e-1)" "unprognostic (6.82e-2)" "unprognostic (6.67e-2)" "unprognostic (3.83e-2)" "prognostic unfavorable (1.10e-6)" "prognostic unfavorable (7.88e-4)" "unprognostic (1.30e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (4.15e-6)" "unprognostic (1.80e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.27e-1)" "unprognostic (2.75e-1)" "unprognostic (2.13e-1)" "unprognostic (1.60e-1)" 3.8 1.8 0.9 17.0 1.0 53.2 7.4 0.9 1.5 5.2 0.9 17.6 16.3 7.1 12.2 17.5 3.7 4.3 1.4 0.9 1.0 3.1 3.2 4.7 40.6 1.2 1.2 2.3 0.8 2.5 4.1 19.4 1.1 1.7 20.8 1.3 3.2 5.2 1.4 13.2 14.5 8.0 0.9 9.0 10.1 25.1 1.4 74.0 3.6 2.2 47.5 7.1 6.9 1.0 249.9 93.5 241.1 96.0 15.4 23.6 99.0 183.8 132.7 218.8 209.0 218.9 213.7 226.2 69.6 50.6 79.6 149.9 166.2 106.8 225.8 162.3 121.1 119.4 84.4 128.1 2.8 184.5 117.6 4.7 10.4 142.1 137.0 49.6 133.3 146.2 185.1 270.3 246.9 66.3 234.0 131.1 106.6 149.3 193.1 199.7 224.5 111.3 84.3 81.4 112.7 98.7 123.5 184.9 96.3 130.0 199.9 111.5 55.4 92.8 197.9 99.1 255.8 104.9 180.8 205.6 79.9 203.5 117.6 0.0 0.0 0.0 0.3 0.1 0.2 0.5 0.7 1.3 0.3 0.4 0.2 0.7 0.0 3.2 0.1 0.9 3.4 0.9 0.9 1.0 0.9 1.5 0.9 1.0 1.2 1.2 1.1 0.9 1.4 1.0 7.7 0.0 3.2 0.3 7.1 39.8 5.4 29.9 2.8 1.1 5.3 6.1 0.8 0.0 10.2 18.4 0.0 80.9 3.6 8.9 3.9 0.8 18.7 10.8 6.2 10.5 3.0 209.6 0.4 0.0 144.6 13.3 13.3 9.4 0.0 51.5 7.5 1.3 57.2 0.0 0.2 14.6 30.5 20.5 18.1 10.4 2.1 16.5 1.8 1.9 1.0 1.0 3.1 0.0 0.1 0.4 0.7 0.7 32.1 4.3 2.2 3.0 17.6 0.7 0.0 0.5 24.6 110.0 39.6 33.8 18.6 22.0 10.3 2.1 26.6 10.4 CDK10 PISSLRE ENSG00000185324 "Cyclin dependent kinase 10" Q15131 16 89680737-89696354 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007451, HPA059634, HPA067060" Uncertain Supported "Nucleoplasm,Midbody,Midbody ring" Yes Yes "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Midbody, Midbody ring" "HPA007451: AB_2732400, HPA059634: AB_2684090, HPA067060: AB_2685772" "unprognostic (7.89e-2)" "unprognostic (8.08e-2)" "unprognostic (3.74e-3)" "unprognostic (9.87e-2)" "unprognostic (1.76e-1)" "unprognostic (3.44e-2)" "unprognostic (4.53e-1)" "unprognostic (9.06e-2)" "unprognostic (2.99e-1)" "unprognostic (2.13e-1)" "prognostic favorable (2.69e-4)" "unprognostic (2.58e-2)" "unprognostic (2.93e-1)" "unprognostic (3.32e-2)" "unprognostic (1.79e-1)" "unprognostic (6.88e-2)" "prognostic favorable (3.63e-4)" 30.1 38.5 20.2 10.4 20.4 19.5 26.7 20.3 32.8 49.3 22.0 38.2 22.7 25.9 8.7 35.3 36.3 8.6 27.3 21.0 19.5 52.9 77.0 31.0 14.7 18.6 18.7 43.2 49.2 13.5 55.5 12.5 19.6 39.1 11.3 7.6 24.8 7.5 33.8 32.1 36.1 8.2 17.0 37.5 38.5 17.0 18.4 10.8 54.5 4.1 7.0 32.3 36.5 19.1 27.5 17.8 13.9 5.8 5.7 11.0 14.2 22.3 12.6 15.2 4.9 13.1 21.2 23.9 9.8 19.3 9.1 15.5 5.8 30.8 9.3 5.3 14.1 9.7 21.0 1.7 23.4 15.8 17.1 13.3 10.7 9.3 15.3 10.3 27.0 16.1 25.5 3.2 17.7 36.6 19.5 45.0 28.5 29.7 13.1 26.5 19.0 34.1 27.9 21.2 10.1 29.6 28.0 13.0 6.8 15.2 30.3 25.0 24.1 9.1 26.6 10.1 15.4 11.7 6.4 7.5 16.4 25.0 15.5 5.1 14.0 4.2 14.8 19.7 12.8 7.8 13.2 10.7 18.1 9.0 15.1 12.6 1.5 20.4 15.4 12.4 11.6 11.4 20.2 20.4 20.3 32.8 21.0 19.5 18.6 18.7 19.6 17.0 18.4 19.1 28.2 12.8 26.6 35.3 21.2 15.4 24.2 26.9 23.3 17.2 24.5 25.1 6.5 38.6 20.0 27.6 25.0 28.6 26.7 44.8 43.0 28.6 6.1 20.7 21.9 23.0 67.7 15.4 44.5 12.5 19.8 19.6 85.1 16.9 9.5 40.3 21.8 41.1 18.8 18.5 33.3 49.4 26.4 17.4 16.0 8.8 23.9 17.0 19.6 17.8 15.5 8.5 26.8 24.6 20.0 13.6 41.5 12.4 20.8 30.7 58.3 53.7 28.1 32.3 6.6 11.4 16.3 27.3 28.7 22.4 15.5 27.9 22.0 54.8 58.2 22.9 CDKN2C "INK4C, p18" ENSG00000123080 "Cyclin dependent kinase inhibitor 2C" P42773 1 50960745-50974634 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 98.4;lymphoid tissue: 96.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 73.5;Sertoli cells: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "THP-1: 273.1;U-937: 284.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005303, CAB018398, HPA019057, HPA019764" Approved Approved Nucleoplasm,Cytosol NA Yes "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "CAB005303: AB_2078729, CAB018398: AB_2078731, HPA019057: AB_1854865, HPA019764: AB_1854866" "unprognostic (4.07e-2)" "unprognostic (1.47e-3)" "unprognostic (2.89e-1)" "unprognostic (4.86e-2)" "unprognostic (6.70e-2)" "unprognostic (4.76e-3)" "prognostic unfavorable (1.58e-4)" "unprognostic (1.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.71e-1)" "unprognostic (2.28e-1)" "unprognostic (2.38e-1)" "prognostic unfavorable (1.70e-10)" "unprognostic (2.55e-2)" "unprognostic (2.12e-1)" "unprognostic (6.45e-2)" "unprognostic (1.24e-1)" 98.4 23.2 21.6 9.1 23.6 36.0 30.6 22.6 31.4 17.5 20.3 19.3 13.4 20.4 11.8 11.1 15.2 15.5 24.2 21.6 23.0 10.4 7.2 9.9 22.5 23.0 22.4 47.6 17.4 19.9 7.8 7.3 24.0 9.9 12.6 7.8 8.8 24.9 20.5 18.9 14.2 22.2 21.2 11.1 7.4 5.2 22.2 96.2 9.7 8.6 23.4 13.1 16.3 30.3 67.6 32.9 5.9 99.6 108.0 16.4 1.5 61.8 76.2 121.8 107.8 1.8 25.7 140.3 58.5 63.5 41.6 8.2 71.4 9.8 63.4 78.4 90.7 102.5 254.6 21.5 5.5 74.0 42.8 5.6 1.9 32.8 14.6 45.6 32.7 115.0 45.0 0.0 76.2 22.0 91.1 40.4 0.1 31.6 71.3 108.6 86.8 0.4 42.9 34.1 49.6 114.3 88.1 67.5 23.6 0.6 31.3 273.1 21.6 130.8 44.1 76.3 0.9 128.1 131.9 113.2 0.0 284.5 118.3 22.4 3.7 17.9 7.3 2.2 8.4 4.9 10.8 9.7 9.3 4.3 6.0 5.8 0.4 10.5 0.9 11.5 22.0 5.6 21.6 23.6 22.6 31.4 21.6 23.0 23.0 22.4 24.0 21.2 22.2 30.3 9.5 0.0 3.9 2.0 5.6 10.1 2.6 8.1 23.9 8.2 3.8 29.5 14.3 5.7 6.1 3.7 16.7 4.9 11.3 2.8 17.6 6.3 4.9 1.1 18.2 8.1 8.4 73.5 0.6 3.4 12.1 31.0 3.1 1.2 16.5 12.6 20.3 8.8 28.3 5.0 0.6 10.2 14.2 20.5 16.0 7.1 39.4 11.0 7.2 1.9 17.1 26.9 17.5 2.0 3.3 3.1 10.2 47.8 14.0 1.8 24.6 40.8 3.2 9.9 85.5 38.9 26.7 32.0 15.0 22.0 11.2 1.9 18.2 28.6 9.1 1.2 CDKN2D "INK4D, p19" ENSG00000129355 "Cyclin dependent kinase inhibitor 2D" P55273 19 10566460-10569059 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 283.7" "Cell type enhanced" "Detected in all" "dendritic cells: 146.8;Erythroid cells: 116.6;Macrophages: 105.4;NK-cells: 155.5;Spermatocytes: 126.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 90.6;MOLT-4: 113.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011201, HPA043546" Enhanced Supported Nucleoplasm,Cytosol NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm Cytosol "CAB011201: AB_261049, HPA043546: AB_2678545" "unprognostic (3.08e-1)" "prognostic favorable (1.02e-4)" "unprognostic (3.57e-2)" "unprognostic (1.49e-2)" "unprognostic (3.29e-2)" "unprognostic (1.37e-2)" "prognostic unfavorable (4.82e-4)" "unprognostic (2.08e-1)" "unprognostic (1.08e-2)" "unprognostic (6.55e-2)" "unprognostic (3.28e-1)" "unprognostic (1.50e-1)" "unprognostic (3.27e-3)" "unprognostic (9.90e-2)" "unprognostic (4.52e-1)" "unprognostic (4.43e-2)" "unprognostic (1.40e-1)" 13.7 9.8 61.0 13.3 64.9 283.7 9.5 43.9 86.9 9.4 37.3 14.2 6.3 7.0 3.1 14.3 11.0 6.4 18.8 64.8 59.7 11.3 7.1 30.8 23.9 53.8 51.5 7.1 5.8 3.3 15.7 8.2 59.9 8.0 5.6 16.3 7.3 4.1 19.7 18.1 14.5 7.8 46.1 42.4 9.4 38.6 57.6 78.0 6.2 15.9 16.1 11.2 12.9 57.4 30.8 4.8 15.1 10.0 8.0 12.2 3.8 19.8 23.2 21.4 18.8 6.1 7.3 8.5 6.4 21.1 21.6 6.4 5.2 5.1 7.7 34.3 12.6 90.6 5.8 10.2 9.2 9.2 70.2 5.1 16.2 11.0 8.2 17.7 6.1 52.6 3.8 72.3 21.5 4.3 113.9 48.3 3.0 23.4 22.7 18.4 14.7 5.1 9.7 2.6 21.3 11.2 14.0 10.4 15.2 2.8 9.4 24.0 4.7 25.2 12.9 42.1 30.1 44.9 16.5 15.8 26.7 15.5 18.4 143.5 17.7 79.7 30.2 23.2 24.2 56.7 24.9 34.1 17.4 50.0 23.3 27.4 139.9 41.1 35.6 51.0 22.5 31.8 61.0 64.9 43.9 86.9 64.8 59.7 53.8 51.5 59.9 46.1 57.6 57.4 35.2 6.4 7.0 4.6 65.2 23.2 13.7 17.1 38.7 32.4 11.1 15.2 9.2 5.7 8.2 5.5 12.5 4.8 146.8 11.8 9.8 7.7 21.2 26.9 10.2 29.3 7.2 116.6 18.5 4.9 8.4 11.0 3.6 16.7 21.0 4.8 26.7 3.8 10.4 47.1 14.8 6.4 36.7 42.2 47.7 13.7 7.2 105.4 30.2 1.9 46.4 22.2 155.5 1.0 8.2 14.2 9.4 6.0 9.2 11.4 5.0 5.1 10.9 37.1 19.7 8.3 25.8 126.0 83.7 38.6 33.1 4.9 63.4 4.5 6.9 23.8 CDKN3 "CDI1, KAP" ENSG00000100526 "Cyclin dependent kinase inhibitor 3" Q16667 14 54396849-54420218 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 207.0" "Cell type enhanced" "Detected in many" "Early spermatids: 2630.9;Late spermatids: 659.4;Spermatocytes: 606.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 18.8" "Group enriched" "Detected in all" 6 "NK-cells: 6.4;T-cells: 18.8" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005285, HPA039311, HPA058874" Enhanced Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "CAB005285: AB_2078884, HPA039311: , HPA058874: AB_2683842" "unprognostic (3.46e-2)" "unprognostic (9.95e-2)" "unprognostic (5.79e-2)" "unprognostic (6.78e-3)" "unprognostic (2.73e-1)" "unprognostic (6.08e-2)" "unprognostic (1.51e-3)" "prognostic unfavorable (4.52e-4)" "unprognostic (2.50e-3)" "unprognostic (2.85e-3)" "prognostic unfavorable (7.46e-4)" "unprognostic (5.89e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.71e-1)" "unprognostic (7.30e-2)" "unprognostic (7.92e-2)" "unprognostic (4.31e-2)" 3.4 1.6 2.8 12.2 2.7 43.4 3.4 5.0 4.2 2.2 3.4 13.9 12.4 2.8 0.4 10.2 1.3 2.9 5.3 2.9 3.1 2.0 2.4 2.1 28.4 2.5 2.7 1.3 1.1 0.5 1.6 6.7 3.3 1.6 16.9 2.6 3.3 0.7 3.0 5.9 12.6 7.4 2.1 4.9 5.0 207.0 3.5 30.9 1.7 4.1 30.0 5.8 4.1 2.6 276.7 102.5 74.0 78.2 12.5 15.3 46.5 63.1 97.0 135.8 146.9 81.8 136.5 139.9 44.4 96.7 135.9 195.9 114.6 78.3 245.6 169.5 59.3 65.8 69.0 126.8 10.1 86.2 47.6 5.4 4.9 84.3 138.3 44.4 88.4 129.8 36.1 162.2 159.8 186.9 118.1 67.9 27.9 254.7 216.4 72.7 66.6 29.7 70.5 56.9 30.6 42.0 118.7 67.4 52.5 54.6 142.9 69.4 33.0 59.2 195.8 91.7 155.0 38.6 47.4 91.4 98.6 120.4 110.9 0.0 1.3 1.3 1.6 1.7 0.7 2.1 5.5 4.8 1.8 0.9 2.9 2.3 1.0 6.4 1.2 1.5 18.8 3.1 2.8 2.7 5.0 4.2 2.9 3.1 2.5 2.7 3.3 2.1 3.5 2.6 1.4 0.0 0.0 0.7 10.5 9.3 4.3 9.7 4.6 3.2 6.4 11.6 9.7 0.0 2.4 1.8 2.1 42.6 2.7 7.3 0.0 3.5 2630.9 2.7 3.5 6.8 7.8 125.5 2.5 2.4 35.0 10.2 9.2 3.5 7.0 31.3 6.1 3.1 37.7 5.0 3.9 17.9 4.1 9.8 8.8 659.4 21.5 8.9 1.8 1.0 2.9 1.7 0.0 0.0 0.2 1.9 7.2 10.5 41.0 4.0 3.4 2.8 0.2 2.9 0.0 3.0 20.5 606.9 39.8 22.5 6.5 4.1 8.3 3.9 31.2 5.3 CDT1 "DUP, RIS2" ENSG00000167513 "Chromatin licensing and DNA replication factor 1" Q9H211 16 88803789-88809258 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" "Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "bone marrow: 38.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 51.4;Erythroid cells: 71.3;Extravillous trophoblasts: 92.0;Spermatogonia: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NB-4: 149.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA017224 Approved Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA017224: AB_1846468" "unprognostic (1.33e-1)" "unprognostic (2.04e-2)" "unprognostic (7.32e-2)" "unprognostic (2.67e-1)" "unprognostic (4.34e-1)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.12e-6)" "unprognostic (3.44e-3)" "unprognostic (2.81e-2)" "unprognostic (4.59e-2)" "unprognostic (1.21e-1)" "unprognostic (9.34e-2)" "prognostic unfavorable (2.69e-6)" "unprognostic (7.72e-3)" "unprognostic (5.79e-2)" "unprognostic (2.80e-2)" "unprognostic (8.54e-2)" 0.7 0.8 0.8 3.8 1.2 38.5 0.7 2.5 1.3 1.7 0.0 3.3 4.1 0.5 0.2 6.7 0.5 0.2 0.5 0.8 2.3 0.7 1.0 1.3 4.8 2.2 1.1 0.4 0.6 1.3 2.1 2.8 1.9 0.7 1.6 0.4 1.1 0.2 0.1 3.6 3.9 0.6 0.7 3.1 2.4 3.5 1.1 8.7 0.6 0.0 3.3 0.5 2.3 1.0 33.6 34.5 16.5 25.3 0.7 3.4 64.2 24.1 6.6 19.4 12.0 79.3 33.8 51.4 24.2 5.5 12.7 46.0 21.6 17.7 6.2 18.2 92.1 51.8 28.8 59.9 0.3 28.8 21.5 1.8 1.4 19.8 4.4 1.6 5.9 60.9 80.8 18.4 7.6 90.6 109.3 149.4 41.8 12.2 31.6 120.3 22.9 42.4 4.3 23.8 36.6 26.2 44.4 13.1 16.9 7.4 39.0 55.9 5.9 24.6 42.6 37.2 35.4 61.4 55.7 73.6 19.3 71.9 31.6 0.2 0.1 0.9 0.3 0.0 0.0 0.1 0.1 0.2 0.3 0.2 0.1 0.1 0.7 0.4 0.1 0.1 0.7 0.2 0.8 1.2 2.5 1.3 0.8 2.3 2.2 1.1 1.9 0.7 1.1 1.0 0.4 0.0 1.1 0.7 4.9 11.2 4.3 1.4 7.4 0.7 5.4 7.5 2.2 1.5 1.7 1.8 0.0 51.4 2.2 12.7 1.9 1.1 0.4 1.4 1.4 2.2 2.4 71.3 0.2 0.0 92.0 5.2 9.2 2.2 0.0 29.0 0.4 1.0 19.5 0.0 0.8 16.1 4.1 5.6 5.5 1.2 0.3 2.8 1.8 0.0 1.9 1.5 4.1 0.0 0.6 0.6 2.3 0.4 23.1 2.2 2.0 1.6 2.1 1.9 0.0 2.1 3.4 6.6 37.1 10.8 7.1 24.8 5.4 5.7 30.1 4.4 CENPA "CenH3, CENP-A" ENSG00000115163 "Centromere protein A" P49450 2 26764289-26801067 "Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 13.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 45.0;Extravillous trophoblasts: 33.2;Granulosa cells: 24.2;Plasma cells: 17.8;Spermatogonia: 28.6" "Cancer enhanced" "Detected in many" "testis cancer: 24.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB008371, HPA073086" Enhanced Supported Nucleoplasm NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB008371: AB_591074, HPA073086: AB_2686569" "unprognostic (3.94e-2)" "unprognostic (1.38e-1)" "unprognostic (2.29e-2)" "prognostic unfavorable (2.38e-4)" "unprognostic (1.13e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (2.88e-8)" "prognostic unfavorable (3.70e-4)" "unprognostic (1.69e-3)" "unprognostic (7.80e-2)" "prognostic unfavorable (1.30e-4)" "unprognostic (4.21e-3)" "unprognostic (0.00e+0)" "unprognostic (5.74e-2)" "unprognostic (1.33e-1)" "unprognostic (7.68e-2)" "unprognostic (2.07e-1)" 0.2 0.3 0.0 4.0 0.0 3.7 0.4 0.1 0.1 0.5 0.0 2.9 4.1 0.7 0.0 3.7 0.1 0.1 0.2 0.0 0.0 0.1 0.2 0.4 7.3 0.0 0.0 0.1 0.1 0.0 0.0 1.5 0.0 0.1 2.6 0.0 0.6 0.0 0.0 3.6 2.9 0.9 0.0 2.0 1.6 2.2 0.1 13.3 0.1 0.0 8.4 0.7 1.1 0.0 86.4 21.0 34.9 19.3 2.4 4.5 24.3 26.2 22.2 37.3 31.5 15.4 30.0 25.7 16.2 10.4 45.7 25.6 28.9 15.3 37.7 77.3 25.6 44.0 11.0 28.6 0.8 26.7 49.0 0.4 1.6 16.1 24.4 6.7 22.1 33.7 36.7 58.5 32.5 30.1 39.0 42.2 26.6 35.3 34.3 45.4 53.6 30.8 17.5 5.5 27.5 26.7 25.7 32.7 23.6 12.9 18.2 27.2 12.6 23.9 54.2 27.9 46.4 51.5 53.5 107.3 11.1 54.7 46.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 5.2 6.2 0.7 1.9 1.8 0.0 2.0 2.5 2.7 0.0 0.5 0.0 0.0 15.3 1.0 2.3 0.0 0.5 0.6 1.6 1.6 1.5 4.2 45.0 0.1 0.2 33.2 4.9 2.6 3.0 0.0 24.2 3.9 0.6 15.7 0.0 0.1 6.6 0.0 2.9 2.8 0.1 0.9 4.4 1.8 0.0 0.0 0.0 1.0 0.0 0.0 0.1 1.4 0.0 17.8 2.1 0.8 0.2 0.1 0.0 0.0 0.6 3.9 16.1 28.6 12.5 5.3 3.4 3.4 1.5 11.1 2.0 CENPC "CENP-C, CENPC1, hcp-4, MIF2" ENSG00000145241 "Centromere protein C" Q03188 4 67468762-67545503 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049740, HPA058252" Supported "Nucleoplasm,Nuclear bodies,Kinetochore,Midbody" Yes Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 21: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear bodies, Kinetochore" "Nucleoplasm, Midbody" "HPA049740: , HPA058252: AB_2683654" "unprognostic (4.35e-1)" "unprognostic (6.41e-3)" "unprognostic (4.31e-3)" "unprognostic (7.85e-2)" "unprognostic (6.31e-2)" "unprognostic (3.85e-3)" "unprognostic (6.40e-2)" "prognostic favorable (9.67e-4)" "unprognostic (3.22e-2)" "unprognostic (7.13e-2)" "unprognostic (8.35e-2)" "unprognostic (4.32e-2)" "prognostic favorable (5.63e-4)" "unprognostic (2.40e-1)" "unprognostic (1.92e-1)" "unprognostic (1.15e-1)" "unprognostic (1.92e-3)" 1.5 1.6 2.5 1.0 3.2 3.6 3.3 5.6 2.6 2.8 0.2 2.0 1.1 3.1 2.3 1.5 2.9 1.1 1.5 2.2 2.0 2.0 1.4 1.5 1.8 1.3 1.8 5.6 3.8 1.5 2.5 1.3 1.7 2.9 1.2 2.7 2.0 1.6 1.1 2.3 1.8 1.5 1.3 2.0 2.1 1.7 1.7 2.0 3.1 1.1 1.5 2.0 2.3 2.8 0.4 0.5 1.6 0.9 1.9 1.1 0.9 0.6 0.5 0.7 0.5 0.7 1.3 2.7 0.8 0.8 0.2 0.8 2.2 0.9 1.2 0.8 0.4 2.1 0.9 0.9 0.6 3.9 0.8 1.4 0.3 0.5 1.3 1.2 0.4 1.8 3.0 1.6 1.1 0.7 5.3 3.5 1.8 0.8 0.3 2.4 4.0 0.9 1.0 0.8 2.8 1.3 1.2 2.5 0.7 1.6 0.7 1.3 0.4 1.0 0.5 0.7 0.5 1.3 0.5 2.7 1.1 2.2 0.6 0.5 0.2 0.5 0.7 0.4 0.3 0.8 0.8 0.9 0.2 1.1 1.2 0.9 0.2 0.5 0.2 0.4 0.4 0.2 2.5 3.2 5.6 2.6 2.2 2.0 1.3 1.8 1.7 1.3 1.7 2.8 53.1 32.1 35.5 38.8 68.4 15.2 25.3 17.7 35.9 53.7 26.0 32.3 24.3 18.6 31.6 16.5 14.6 20.2 75.0 17.7 11.7 13.5 4.1 21.0 39.0 33.7 13.1 31.7 58.5 16.7 12.9 41.3 35.7 25.1 26.6 39.8 23.2 14.1 12.8 52.2 57.0 18.4 18.3 16.7 7.9 5.5 34.8 26.7 16.0 31.9 27.4 31.6 60.8 46.3 74.6 14.6 13.0 25.6 89.1 15.3 24.2 20.4 27.2 29.0 19.7 54.1 34.2 47.2 44.4 34.7 9.2 18.3 69.8 43.3 16.4 23.9 CENPE "KIF10, PPP1R61" ENSG00000138778 "Centromere protein E" Q02224 4 103105349-103198445 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Developmental protein, Motor protein" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 10.0;lymphoid tissue: 9.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 75.1;Extravillous trophoblasts: 28.4;Granulosa cells: 32.0;Spermatocytes: 75.3;Spermatogonia: 51.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA011110, HPA042294" Enhanced Enhanced "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA011110: , HPA042294: AB_10797386" "unprognostic (1.62e-1)" "unprognostic (1.03e-1)" "unprognostic (5.64e-3)" "unprognostic (2.55e-2)" "unprognostic (1.65e-1)" "unprognostic (3.44e-2)" "unprognostic (2.40e-8)" "unprognostic (2.49e-3)" "unprognostic (1.59e-2)" "unprognostic (3.38e-1)" "unprognostic (4.88e-5)" "unprognostic (1.15e-2)" "unprognostic (0.00e+0)" "unprognostic (9.95e-3)" "unprognostic (2.49e-1)" "unprognostic (1.05e-1)" "unprognostic (2.37e-1)" 0.4 0.2 0.4 2.7 0.4 10.0 0.6 0.3 0.5 0.4 0.4 1.8 1.5 0.6 0.0 2.0 0.2 0.8 0.2 0.3 0.6 0.2 0.5 0.8 5.6 0.5 0.5 0.1 0.1 0.3 0.0 1.4 0.9 0.3 2.0 0.4 0.3 0.2 0.0 2.0 1.7 1.1 0.3 1.2 1.1 4.1 0.5 9.2 0.2 0.6 4.9 0.8 0.6 0.5 42.6 11.8 42.2 20.5 2.7 6.2 8.4 36.7 18.2 26.9 17.9 19.6 22.2 28.6 9.2 13.7 19.2 18.2 30.3 15.1 42.2 35.9 11.3 33.5 26.8 13.6 0.4 39.9 18.6 1.8 1.1 21.7 18.0 6.0 22.9 25.2 34.4 32.5 34.8 15.6 31.5 18.9 13.8 17.0 17.9 20.9 38.5 9.3 8.0 8.4 19.3 11.5 32.9 22.9 9.0 16.0 12.9 13.9 26.1 25.8 27.2 27.2 38.6 15.9 28.6 28.8 14.2 21.7 27.8 2.9 0.0 0.3 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.3 1.5 0.2 0.6 0.0 0.4 0.4 0.3 0.5 0.3 0.6 0.5 0.5 0.9 0.3 0.5 0.5 1.4 3.2 2.2 1.0 6.6 3.6 1.5 2.9 0.0 7.6 1.8 2.7 1.9 0.0 1.3 0.0 8.4 12.7 3.9 4.7 0.0 0.5 7.7 3.5 5.7 4.2 1.2 75.1 2.0 0.0 28.4 6.5 4.6 6.9 7.0 32.0 4.2 0.9 14.1 0.0 1.9 4.3 4.1 10.4 5.7 3.5 0.9 9.6 0.0 0.0 6.0 1.3 2.1 0.5 3.1 1.8 1.4 2.6 16.0 1.4 0.8 0.3 0.3 2.6 0.0 5.7 7.4 75.3 51.0 8.3 2.8 3.6 6.6 7.0 11.6 1.9 CENPF hcp-1 ENSG00000117724 "Centromere protein F" P49454 1 214603195-214664571 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, DNA synthesis, Mitosis, Myogenesis" "Developmental protein" "Cancer-related genes, Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.8;lymphoid tissue: 33.0" "Cell type enhanced" "Detected in many" "Early spermatids: 84.4;Erythroid cells: 268.7;Extravillous trophoblasts: 78.8;Granulosa cells: 165.8;Spermatocytes: 107.5;Spermatogonia: 107.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "HPA052382, HPA064308, CAB070134" Enhanced Supported Nucleoplasm Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB070134: AB_2229328, HPA052382: AB_2681808, HPA064308: AB_2732711" "unprognostic (2.80e-1)" "unprognostic (2.16e-1)" "unprognostic (2.65e-1)" "unprognostic (5.30e-2)" "unprognostic (1.73e-1)" "unprognostic (2.40e-2)" "prognostic unfavorable (2.29e-5)" "unprognostic (1.13e-2)" "unprognostic (2.58e-3)" "unprognostic (1.11e-1)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.58e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.92e-2)" "unprognostic (1.71e-1)" "unprognostic (1.89e-2)" "unprognostic (4.12e-1)" 0.8 1.1 0.1 4.4 0.1 28.8 1.8 0.0 0.3 1.3 0.5 5.8 6.1 1.8 0.1 8.6 0.6 0.7 0.4 0.3 0.0 0.4 0.9 0.9 8.5 0.3 0.5 0.7 0.3 0.2 0.1 3.1 0.3 0.5 5.7 1.0 1.4 0.1 0.2 6.2 4.3 2.5 0.2 2.4 2.6 10.5 0.5 33.0 0.4 0.6 10.0 1.4 2.6 0.3 123.7 68.4 144.3 75.8 5.4 7.2 56.3 74.6 30.3 43.9 42.8 54.6 74.1 116.3 43.1 41.7 39.8 74.7 89.9 49.2 74.1 102.6 56.6 96.0 111.4 78.6 0.8 137.0 50.5 2.7 3.8 63.3 72.3 12.7 46.9 52.6 88.4 68.0 79.4 47.0 81.5 54.3 127.9 36.8 30.0 85.7 203.7 38.6 43.2 30.3 67.4 91.2 100.7 66.2 38.9 76.2 79.1 51.9 61.7 78.9 92.2 66.2 155.9 51.6 60.7 108.7 34.4 96.7 71.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.3 0.3 0.0 0.3 0.5 0.3 0.2 0.5 0.3 3.0 0.0 3.1 0.0 11.5 9.3 2.8 11.2 3.4 4.7 10.0 6.7 1.9 1.5 9.9 0.0 0.0 53.3 10.8 19.1 0.0 2.0 84.4 30.1 19.3 12.4 0.0 268.7 1.3 0.4 78.8 19.0 32.1 25.2 1.3 165.8 8.9 2.6 32.2 1.7 0.8 20.1 14.2 16.6 6.6 19.8 1.2 16.2 1.8 1.0 0.7 1.4 5.2 0.0 0.1 0.5 1.1 3.0 25.9 2.3 2.1 0.1 16.7 3.1 0.0 8.3 23.9 107.5 107.1 44.6 5.5 5.1 23.3 11.7 41.3 3.7 CENPI "CENP-I, FSHPRH1, LRPR1, Mis6" ENSG00000102384 "Centromere protein I" Q92674 X 101098218-101163681 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 6.8;lymphoid tissue: 7.1" "Cell type enhanced" "Detected in some" "Erythroid cells: 4.8;Excitatory neurons: 2.9;Extravillous trophoblasts: 4.7;Granulosa cells: 3.2;Oligodendrocytes: 3.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA061297 Supported "Nuclear bodies,Cytosol" NA Yes "Cluster 33: Neutrophils - Chromatin organization" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies" Cytosol "HPA061297: AB_2684471" "unprognostic (3.10e-3)" "unprognostic (9.71e-2)" "unprognostic (1.86e-2)" "unprognostic (3.51e-3)" "unprognostic (1.24e-1)" "unprognostic (2.46e-2)" "unprognostic (5.78e-6)" "unprognostic (2.96e-2)" "unprognostic (7.71e-3)" "unprognostic (3.62e-3)" "unprognostic (1.20e-3)" "unprognostic (4.51e-2)" "unprognostic (2.50e-13)" "unprognostic (1.25e-2)" "unprognostic (1.47e-1)" "unprognostic (1.55e-1)" "unprognostic (1.42e-1)" 1.1 0.6 0.9 3.1 1.0 6.8 1.2 2.0 1.0 1.0 0.5 2.7 2.8 1.8 1.4 2.6 0.6 1.4 0.5 1.1 1.1 0.4 0.8 1.0 5.4 1.4 0.6 2.3 0.9 0.2 0.0 2.5 1.4 1.2 3.5 1.8 0.5 0.6 0.2 3.2 2.3 2.7 0.1 1.6 1.5 1.2 1.0 7.1 0.8 0.6 6.3 1.4 0.8 2.9 44.9 30.3 36.6 28.1 4.6 8.2 16.4 47.5 25.2 47.1 94.5 40.9 28.0 32.7 16.5 18.8 72.5 25.7 54.2 25.3 65.4 20.6 13.8 20.2 43.5 15.6 0.5 26.8 21.2 3.3 2.2 62.5 7.7 13.5 40.7 23.3 14.5 58.3 46.1 31.5 26.7 9.8 28.3 21.2 36.8 24.7 53.0 21.0 11.8 26.4 23.4 12.3 58.1 16.3 9.6 33.0 16.2 8.6 16.7 44.0 36.6 41.2 38.3 9.1 23.3 36.5 17.3 35.2 34.7 0.7 0.5 0.6 0.4 0.7 0.3 0.6 0.4 0.6 0.2 0.4 0.4 0.4 1.1 0.7 0.7 0.7 0.8 0.3 0.9 1.0 2.0 1.0 1.1 1.1 1.4 0.6 1.4 0.1 1.0 2.9 0.5 0.0 0.0 2.3 0.9 0.3 0.1 0.6 0.0 0.5 0.4 0.3 0.4 0.0 0.7 0.0 0.0 1.9 0.5 0.8 0.0 0.2 0.2 0.4 0.8 0.5 0.0 4.8 2.9 0.0 4.7 0.6 0.0 0.6 0.0 3.2 0.7 0.2 1.4 0.0 2.3 0.7 0.0 0.6 0.8 0.0 0.3 0.3 0.0 1.0 0.6 0.5 0.0 1.5 3.3 0.1 0.0 0.0 0.7 0.2 0.1 0.0 0.1 0.3 0.0 0.7 1.0 0.3 0.9 1.4 0.1 0.3 0.4 0.8 1.4 0.2 CENPK "CENP-K, FKSG14, SOLT" ENSG00000123219 "Centromere protein K" Q9BS16 5 65517766-65563168 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.6;lymphoid tissue: 22.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 50.9;Extravillous trophoblasts: 50.6;Spermatocytes: 101.3;Spermatogonia: 75.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA Yes "Cluster 20: T-cells - T-cell receptor" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "unprognostic (4.04e-2)" "unprognostic (1.77e-2)" "unprognostic (1.57e-2)" "unprognostic (5.04e-2)" "unprognostic (1.85e-1)" "unprognostic (3.04e-3)" "unprognostic (3.69e-4)" "unprognostic (3.22e-3)" "unprognostic (9.59e-3)" "unprognostic (3.32e-2)" "unprognostic (3.16e-3)" "unprognostic (1.98e-2)" "unprognostic (6.33e-15)" "unprognostic (2.22e-1)" "unprognostic (2.97e-1)" "unprognostic (8.42e-2)" "unprognostic (3.11e-1)" 1.1 0.9 0.6 10.6 0.7 24.6 3.8 1.0 0.8 1.2 1.6 9.0 8.3 1.9 0.9 5.6 2.3 1.9 0.5 0.5 0.6 0.8 1.9 2.0 14.6 1.0 0.7 0.8 0.6 1.0 0.3 5.5 1.1 1.3 11.9 0.7 1.4 0.7 0.2 8.6 8.6 3.4 0.7 4.5 5.5 13.4 1.0 22.2 1.2 0.5 12.4 2.6 2.4 1.4 65.3 41.4 85.6 29.5 4.4 12.0 40.8 69.8 26.5 58.7 73.6 35.1 97.2 39.3 25.2 23.6 59.5 39.7 33.3 35.4 92.7 45.2 28.5 42.1 50.7 33.8 1.7 50.1 36.8 5.6 5.0 56.9 27.3 10.6 56.4 42.2 31.8 57.7 59.1 21.5 85.4 56.2 41.1 18.5 17.1 52.5 81.9 43.8 38.8 34.4 35.8 28.9 53.7 22.1 28.7 31.8 40.0 36.9 20.3 44.9 46.5 31.1 82.2 30.0 51.9 83.0 41.9 74.0 49.9 3.7 0.7 2.3 9.9 1.0 14.8 4.0 21.1 12.5 1.7 7.0 28.5 20.2 1.7 10.2 1.1 1.6 23.2 10.0 0.6 0.7 1.0 0.8 0.5 0.6 1.0 0.7 1.1 0.7 1.0 1.4 2.7 0.0 3.4 0.3 11.7 23.6 8.5 14.0 4.6 1.6 6.0 7.9 0.9 0.0 8.1 0.0 0.0 28.8 18.7 5.8 1.9 3.1 27.6 25.5 4.5 5.7 0.0 50.9 3.1 1.0 50.6 6.3 9.2 7.2 2.5 22.7 3.9 1.1 22.4 0.0 2.3 14.7 8.2 1.9 12.0 17.4 1.5 5.7 1.8 11.2 1.8 0.6 7.2 2.0 1.4 2.3 2.1 1.5 14.1 2.2 1.1 0.3 7.1 1.1 0.0 2.3 9.1 101.3 75.1 17.0 8.1 6.7 20.7 3.9 15.8 11.4 CENPL "C1orf155, dJ383J4.3, FLJ31044" ENSG00000120334 "Centromere protein L" Q8N0S6 1 173799550-173824720 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.6;testis: 9.8" "Cell type enhanced" "Detected in many" "Spermatocytes: 38.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA044520 Uncertain NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA044520: AB_10794500" "unprognostic (8.72e-3)" "unprognostic (2.82e-2)" "unprognostic (3.39e-1)" "unprognostic (1.34e-3)" "unprognostic (7.89e-2)" "unprognostic (7.88e-3)" "unprognostic (6.43e-6)" "unprognostic (8.18e-2)" "prognostic unfavorable (2.51e-4)" "prognostic favorable (3.60e-4)" "unprognostic (1.78e-3)" "unprognostic (5.00e-2)" "unprognostic (1.46e-10)" "unprognostic (2.16e-2)" "unprognostic (4.41e-2)" "unprognostic (3.10e-2)" "unprognostic (3.09e-1)" 2.1 1.2 1.4 3.1 1.5 9.6 2.4 1.4 1.8 1.9 1.0 2.4 2.3 1.8 1.0 2.3 1.2 1.7 1.7 1.2 1.3 1.4 1.0 1.3 6.6 1.7 1.3 1.6 0.7 1.1 0.6 3.0 1.6 1.3 3.0 1.5 1.4 1.2 1.4 2.2 1.8 2.4 1.6 2.1 2.1 9.8 1.3 9.1 1.7 2.7 5.7 1.9 1.4 1.8 27.5 7.3 13.5 18.2 3.9 6.7 9.9 23.6 14.4 24.9 17.3 9.5 14.3 19.8 11.0 12.9 9.4 17.6 14.6 11.6 27.4 18.0 7.2 14.6 7.6 5.5 1.9 22.4 14.7 3.4 3.9 17.6 14.0 4.7 14.8 15.2 25.8 28.6 23.0 6.4 18.5 10.3 14.1 19.3 40.4 18.9 16.7 16.7 8.9 7.5 13.6 11.3 18.7 22.5 15.7 10.9 15.8 18.5 8.6 28.6 19.6 14.8 27.6 15.9 29.2 31.5 9.4 16.4 26.6 3.9 1.0 2.4 4.7 1.1 5.3 3.3 4.3 5.5 0.9 5.0 5.5 6.0 0.6 8.6 0.7 4.3 7.1 2.6 1.4 1.5 1.4 1.8 1.2 1.3 1.7 1.3 1.6 1.6 1.3 1.8 16.0 9.6 3.7 1.6 8.5 4.7 6.9 2.8 1.2 4.9 7.3 24.5 5.0 2.8 2.1 1.8 14.6 9.2 13.1 4.8 0.0 2.2 2.2 4.6 12.8 6.3 1.8 22.7 2.2 3.8 15.9 7.7 3.1 7.9 4.5 13.1 3.3 0.8 6.7 1.7 2.0 4.8 2.0 4.4 7.1 3.3 4.7 4.5 5.4 2.8 3.6 2.4 7.2 1.5 2.5 3.6 4.5 1.9 7.4 6.3 4.0 1.3 1.7 4.7 0.0 14.5 10.7 38.8 20.2 8.8 6.0 5.9 9.2 11.2 5.3 4.5 CENPQ "C6orf139, CENP-Q, FLJ10545" ENSG00000031691 "Centromere protein Q" Q7L2Z9 6 49463370-49493107 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatogonia: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029043, HPA046634, HPA054965" Approved Supported Nucleoplasm NA Yes "Cluster 37: B-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA029043: AB_2672881, HPA046634: AB_2679728, HPA054965: AB_2682653" "unprognostic (7.39e-2)" "unprognostic (7.33e-2)" "unprognostic (1.37e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (2.49e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (2.21e-5)" "unprognostic (1.36e-1)" "unprognostic (1.76e-2)" "prognostic favorable (6.26e-4)" "unprognostic (2.89e-1)" "unprognostic (8.19e-2)" "unprognostic (1.48e-3)" "unprognostic (8.93e-2)" "unprognostic (7.47e-2)" "unprognostic (2.74e-3)" "unprognostic (2.56e-1)" 4.8 4.7 4.7 5.4 5.8 4.9 5.4 5.8 6.9 3.1 3.8 3.9 2.8 4.7 3.0 4.3 4.0 3.5 6.4 4.2 5.1 3.8 4.4 3.8 7.0 5.8 5.2 6.2 2.5 3.6 2.3 5.9 6.0 4.5 4.7 4.2 2.8 3.3 5.0 4.0 3.3 4.4 5.3 4.7 3.8 6.0 4.8 9.4 3.7 8.4 8.4 3.7 3.3 7.6 35.3 9.7 30.1 18.9 8.0 12.4 26.4 44.6 25.5 41.9 58.4 11.9 13.8 23.7 21.7 12.7 32.8 12.5 15.8 16.2 61.6 25.9 22.0 17.5 14.6 19.2 3.4 37.4 21.2 5.7 8.7 51.5 17.9 10.7 15.5 20.4 27.3 22.9 31.4 10.2 26.4 17.6 18.8 30.6 8.7 18.8 35.6 25.8 12.3 14.3 16.2 16.0 21.0 12.4 23.9 29.6 15.9 33.8 9.2 32.3 25.2 25.7 40.4 10.4 28.9 21.4 21.9 27.8 32.0 2.2 1.2 4.1 2.0 1.4 2.0 4.4 2.1 2.3 1.3 4.5 2.3 2.3 0.9 2.4 1.8 2.7 3.2 1.2 4.7 5.8 5.8 6.9 4.2 5.1 5.8 5.2 6.0 5.3 4.8 7.6 8.6 0.0 2.7 7.2 9.5 8.7 9.9 10.4 8.6 6.3 4.1 4.7 6.2 4.3 5.2 7.3 2.1 17.3 8.7 4.2 7.9 7.8 1.3 8.8 5.6 8.0 2.4 5.9 3.0 7.9 30.8 9.3 6.6 5.4 4.5 6.3 14.3 3.4 10.1 6.7 3.1 3.7 2.0 11.4 6.0 2.3 8.7 5.9 3.6 11.2 7.6 14.5 13.4 6.6 13.5 7.8 8.0 10.9 7.5 5.4 1.7 4.4 9.4 5.1 6.6 15.2 6.5 17.7 34.6 6.5 7.0 12.4 5.9 4.2 5.9 6.2 CENPU "CENP-50, CENP-U, KLIP1, MLF1IP, PBIP1" ENSG00000151725 "Centromere protein U" Q71F23 4 184694085-184734130 "Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 62.6;testis: 29.5" "Cell type enhanced" "Detected in many" "Early spermatids: 489.7;Late spermatids: 900.3;Spermatocytes: 490.2;Spermatogonia: 215.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "basophil: 20.7;eosinophil: 14.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 20.7" "Cell line enhanced" "Detected in many" "Karpas-707: 157.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA022048 Supported "Nucleoplasm,Centriolar satellite" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Centriolar satellite" "HPA022048: AB_1853985" "unprognostic (1.47e-1)" "unprognostic (9.88e-2)" "unprognostic (5.02e-2)" "unprognostic (2.37e-1)" "unprognostic (9.45e-2)" "unprognostic (4.97e-2)" "unprognostic (4.39e-3)" "prognostic unfavorable (7.51e-4)" "unprognostic (1.67e-3)" "unprognostic (3.34e-2)" "prognostic unfavorable (2.09e-4)" "unprognostic (7.27e-2)" "prognostic unfavorable (1.11e-9)" "unprognostic (2.19e-2)" "unprognostic (7.40e-3)" "unprognostic (4.46e-2)" "unprognostic (2.74e-1)" 1.5 1.1 0.1 5.4 0.3 62.6 5.7 0.6 0.3 2.4 0.1 7.8 5.1 1.5 0.7 10.5 0.9 1.1 1.5 0.2 0.2 0.7 3.7 1.7 16.2 0.2 0.2 0.6 1.0 1.4 0.2 4.8 0.6 1.3 8.0 1.5 2.7 0.4 0.9 15.3 5.4 2.7 0.2 2.3 3.7 29.5 0.4 12.8 1.3 0.1 13.6 2.1 3.9 0.5 57.8 17.1 67.9 35.8 4.3 6.4 37.6 40.8 19.4 32.2 21.2 24.8 32.1 45.9 3.8 18.7 20.2 23.0 52.4 33.2 30.6 23.4 23.0 50.4 17.5 12.6 0.7 71.1 29.3 2.7 2.1 33.3 8.4 9.4 32.1 53.9 44.1 157.3 51.1 38.2 111.4 53.0 33.8 12.7 21.5 74.5 24.3 15.6 17.1 26.7 52.0 49.0 31.4 39.4 23.9 25.0 44.1 50.2 20.9 23.8 31.3 23.5 39.7 26.5 29.5 37.6 37.2 55.4 94.5 20.7 0.7 14.2 0.5 2.0 0.4 0.9 0.7 0.8 0.4 0.9 0.6 0.8 0.1 3.5 2.8 1.9 2.5 0.6 0.1 0.3 0.6 0.3 0.2 0.2 0.2 0.2 0.6 0.2 0.4 0.5 1.4 9.6 3.2 0.3 6.5 13.9 6.0 11.5 3.4 0.9 11.5 7.9 2.3 4.3 8.7 1.8 0.0 31.5 5.4 8.9 3.9 4.8 489.7 9.5 4.0 3.8 0.0 115.7 0.4 2.5 48.4 7.3 9.2 6.6 8.9 27.1 1.1 0.9 21.6 0.0 0.4 10.0 10.2 5.1 7.3 900.3 9.0 15.3 0.0 1.0 5.3 0.2 4.1 0.5 1.9 3.0 1.0 6.8 28.3 2.6 0.9 0.7 5.6 1.4 19.7 2.0 7.2 490.2 215.1 29.1 21.5 7.5 6.3 4.4 18.1 11.6 CEP152 "KIAA0912, MCPH9, SCKL5" ENSG00000103995 "Centrosomal protein 152" O94986 15 48712928-48811146 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant, Dwarfism, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.3" "Cell type enhanced" "Detected in many" "Early spermatids: 192.5;Late spermatids: 49.5;Syncytiotrophoblasts: 46.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA039408 Approved Supported Nucleoplasm,Centrosome NA Yes "Cluster 42: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Centrosome Nucleoplasm "HPA039408: AB_10795288" "unprognostic (3.64e-1)" "unprognostic (1.91e-1)" "unprognostic (2.61e-1)" "unprognostic (4.08e-2)" "unprognostic (2.09e-1)" "unprognostic (3.87e-4)" "unprognostic (4.78e-2)" "unprognostic (8.02e-3)" "unprognostic (1.04e-2)" "unprognostic (5.82e-2)" "unprognostic (4.70e-3)" "unprognostic (3.47e-2)" "unprognostic (6.24e-3)" "unprognostic (5.29e-2)" "unprognostic (3.55e-1)" "unprognostic (4.60e-2)" "unprognostic (1.25e-1)" 2.2 1.3 1.2 3.5 1.4 16.3 1.9 2.0 1.9 1.9 2.6 2.3 2.9 1.4 0.9 2.6 1.9 1.8 2.1 1.0 0.9 2.2 1.0 2.2 4.3 1.2 1.2 2.5 2.9 1.3 0.9 4.7 1.4 1.7 3.1 1.9 2.4 0.9 1.0 3.0 2.9 1.9 0.7 2.4 2.3 9.8 1.8 5.6 2.9 0.6 3.7 1.4 2.3 1.8 8.0 6.1 12.2 15.0 2.1 3.9 7.9 13.9 5.6 10.0 12.3 13.2 6.8 18.6 5.9 4.0 14.1 18.6 13.6 5.0 14.5 16.5 8.3 30.1 34.6 7.2 1.4 25.6 13.4 1.4 3.9 11.1 6.6 3.9 7.5 19.2 18.4 21.6 8.6 4.5 18.6 23.8 7.7 9.5 6.1 22.7 16.4 22.9 3.6 7.5 14.6 9.8 10.7 8.9 4.2 13.3 6.7 12.3 6.2 24.4 12.9 18.9 15.6 9.2 10.8 21.4 7.8 36.2 17.6 2.1 1.0 1.9 0.8 1.4 0.7 0.9 0.9 0.9 0.8 1.7 1.0 1.0 1.8 1.2 1.5 1.5 1.0 0.5 1.2 1.4 2.0 1.9 1.0 0.9 1.2 1.2 1.4 0.7 1.8 1.8 3.9 6.4 2.8 22.2 9.3 3.8 4.1 2.8 4.0 1.5 2.9 3.6 3.9 4.3 1.8 3.7 2.1 31.5 6.8 7.8 0.0 4.7 192.5 6.4 5.3 6.7 3.6 29.9 14.7 6.7 8.5 9.0 7.1 5.0 8.2 20.9 6.1 3.3 7.6 0.0 8.4 8.2 4.1 7.2 6.4 49.5 23.9 8.6 1.8 16.9 6.9 2.9 10.3 6.0 7.0 7.9 3.5 27.1 15.9 3.2 9.1 1.7 8.4 3.6 6.6 6.5 5.4 24.4 10.3 7.0 3.4 46.9 9.9 3.4 10.1 4.1 CEP55 "C10orf3, CT111, FLJ10540" ENSG00000138180 "Centrosomal protein 55" Q53EZ4 10 93496612-93529092 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 27.4;testis: 21.7" "Cell type enhanced" "Detected in many" "Early spermatids: 29.4;Extravillous trophoblasts: 17.1;Granulosa cells: 19.8;Spermatocytes: 77.3;Spermatogonia: 17.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 8 "T-reg: 1.3" "Lineage enriched" "Detected in single" 14 "T-cells: 1.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA023430 Approved Approved "Plasma membrane,Midbody,Centriolar satellite" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Centriolar satellite" Midbody "HPA023430: AB_10960212" "unprognostic (9.85e-2)" "unprognostic (1.12e-2)" "unprognostic (1.04e-1)" "unprognostic (1.29e-1)" "unprognostic (5.15e-2)" "unprognostic (4.26e-2)" "prognostic unfavorable (3.20e-9)" "prognostic unfavorable (1.45e-4)" "unprognostic (1.50e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.66e-5)" "unprognostic (3.99e-2)" "prognostic unfavorable (0.00e+0)" "prognostic favorable (3.15e-4)" "unprognostic (7.86e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" 1.3 0.6 0.0 7.6 0.0 5.0 1.4 0.0 0.2 1.7 0.0 7.0 6.7 1.4 0.1 7.3 0.4 1.4 0.3 0.0 0.1 0.3 0.6 1.3 14.7 0.1 0.3 0.2 0.2 0.2 0.3 3.5 0.2 0.3 8.8 0.0 1.2 0.3 0.1 4.5 6.3 5.2 0.0 2.4 4.6 21.7 0.4 27.4 0.5 0.2 15.5 3.1 2.3 0.1 208.5 81.5 53.0 67.7 5.8 12.0 29.6 112.4 78.2 103.5 106.4 87.2 108.6 55.4 48.2 72.8 69.6 115.4 64.8 54.8 123.4 167.2 33.7 21.0 49.2 29.9 0.6 36.3 46.3 2.8 3.8 110.6 133.5 30.7 97.1 89.9 19.3 101.8 118.5 48.3 96.3 54.8 20.9 64.2 58.8 41.3 86.9 30.3 47.1 25.5 21.7 30.7 86.3 26.3 64.9 40.1 68.9 36.4 61.4 65.3 90.6 90.5 186.7 45.1 66.1 66.8 51.0 134.8 59.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.3 0.2 0.0 0.4 0.1 0.2 0.0 1.3 0.0 2.7 3.6 0.9 1.9 0.0 0.0 1.8 2.0 0.4 2.8 0.2 0.0 0.0 7.7 0.9 3.3 0.0 0.6 29.4 1.7 2.0 1.5 0.0 2.5 0.5 0.2 17.1 2.3 8.2 3.6 0.0 19.8 2.2 0.3 12.9 0.0 0.3 4.5 4.1 7.0 5.1 8.2 0.3 5.1 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.3 0.0 0.4 14.8 1.1 0.4 0.0 0.2 0.0 0.0 0.5 4.5 77.3 17.3 16.1 1.3 1.5 4.3 1.6 7.9 1.7 CFLAR "c-FLIP, CASH, CASP8AP1, Casper, cFLIP, CLARP, FLAME, FLIP, I-FLICE, MRIT" ENSG00000003402 "CASP8 and FADD like apoptosis regulator" O15519 2 201116154-201176687 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 609.9;Urothelial cells: 521.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "neutrophil: 392.6" "Lineage enriched" "Detected in all" 6 "granulocytes: 392.6" "Cell line enhanced" "Detected in all" "U-266/70: 214.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019044, CAB022157, CAB025216" Uncertain Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA Yes "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Plasma membrane, Cytosol" "Nuclear bodies" "CAB022157: , CAB025216: , HPA019044: AB_10696204" "unprognostic (4.61e-2)" "unprognostic (5.32e-2)" "unprognostic (2.49e-1)" "unprognostic (1.44e-1)" "unprognostic (2.95e-2)" "prognostic favorable (2.79e-4)" "unprognostic (7.46e-2)" "unprognostic (9.01e-2)" "unprognostic (1.76e-1)" "unprognostic (6.12e-2)" "unprognostic (3.08e-2)" "unprognostic (4.91e-2)" "unprognostic (2.90e-2)" "unprognostic (7.83e-2)" "unprognostic (9.13e-2)" "unprognostic (6.84e-2)" "unprognostic (2.24e-2)" 122.4 50.6 38.8 103.9 40.9 247.6 83.1 54.1 47.4 57.0 75.6 86.0 59.2 57.9 60.6 68.0 66.6 71.6 184.8 39.4 32.7 57.5 59.2 174.6 91.1 46.5 40.5 38.3 40.7 31.8 29.4 94.0 42.1 65.6 56.4 12.4 58.0 63.2 222.8 51.0 64.8 58.8 36.6 98.1 56.5 25.3 51.9 54.1 78.8 89.2 107.3 78.7 61.7 46.1 21.5 42.9 30.0 17.9 92.3 71.0 37.5 53.6 92.1 34.3 41.6 50.4 78.4 5.8 49.6 62.5 41.6 15.5 9.8 40.3 53.9 160.7 29.9 32.3 38.4 82.2 63.6 24.2 102.2 76.8 39.6 58.2 50.3 41.7 176.7 7.3 110.8 131.2 63.1 17.9 11.3 96.3 10.2 17.2 32.7 11.7 7.2 46.5 42.5 44.0 6.6 11.8 35.7 31.2 43.2 19.6 22.1 44.8 193.6 71.0 29.5 26.7 26.1 214.6 76.2 35.9 50.6 19.5 36.3 91.8 60.3 70.3 54.4 61.8 48.4 25.6 46.5 52.1 33.4 20.9 29.5 38.3 392.6 45.2 68.5 23.0 60.7 42.0 38.8 40.9 54.1 47.4 39.4 32.7 46.5 40.5 42.1 36.6 51.9 46.1 191.3 451.9 234.9 30.3 126.4 54.8 229.6 164.9 29.0 10.9 38.9 30.0 205.8 102.9 206.7 69.9 31.3 77.2 166.2 132.5 74.3 148.8 83.3 202.8 75.0 261.0 95.1 59.1 6.9 72.5 34.8 89.5 73.4 219.2 81.6 93.4 201.0 97.5 68.6 13.5 16.8 76.8 40.7 123.2 609.9 44.8 51.9 278.0 97.8 146.1 247.0 23.4 276.0 29.7 56.8 166.4 155.6 49.7 317.8 386.0 116.7 101.5 276.1 30.7 39.5 113.2 77.9 14.4 12.2 33.2 86.1 70.1 168.3 56.1 50.9 521.3 CHAF1A "CAF-1, CAF1, CAF1B, CAF1P150, MGC71229, P150" ENSG00000167670 "Chromatin assembly factor 1 subunit A" Q13111 19 4402640-4445018 "Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, DNA replication" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 31.4" "Cell type enhanced" "Detected in many" "Erythroid cells: 50.3;Spermatocytes: 94.3;Spermatogonia: 103.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 15.7" "Group enriched" "Detected in many" 4 "dendritic cells: 15.7;granulocytes: 4.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB015186 Enhanced Supported Nucleoplasm,Cytosol NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "CAB015186: AB_628065" "unprognostic (1.91e-1)" "prognostic favorable (8.22e-5)" "unprognostic (2.49e-1)" "unprognostic (4.71e-2)" "unprognostic (2.06e-1)" "unprognostic (1.89e-3)" "unprognostic (5.30e-3)" "unprognostic (8.78e-2)" "unprognostic (2.06e-2)" "unprognostic (2.12e-2)" "unprognostic (2.46e-2)" "unprognostic (1.16e-1)" "unprognostic (8.54e-2)" "prognostic favorable (4.15e-6)" "unprognostic (1.71e-1)" "unprognostic (2.11e-3)" "unprognostic (4.03e-2)" 4.9 4.4 3.5 9.7 3.0 31.4 4.8 5.6 6.6 4.7 1.3 6.9 6.5 3.9 2.0 10.2 4.0 2.7 3.9 3.7 3.0 2.4 4.1 4.0 13.4 3.4 3.1 3.7 3.9 3.3 3.7 6.2 3.0 5.8 6.6 3.4 5.5 3.0 12.2 10.8 6.7 4.1 2.4 6.9 5.1 14.5 3.1 16.3 2.9 4.1 10.5 4.7 5.6 4.1 65.8 44.0 71.8 45.3 7.0 8.5 36.7 61.2 24.8 50.5 56.7 53.5 22.8 100.4 24.7 19.6 28.6 50.3 61.6 41.5 59.8 58.1 67.2 62.9 69.4 42.7 3.5 73.7 48.8 4.8 8.6 41.5 17.7 9.4 24.0 54.9 76.8 88.0 31.3 37.8 119.2 40.7 80.1 33.5 35.6 87.2 56.8 57.2 13.1 76.7 50.6 39.2 41.6 29.1 24.5 45.2 25.7 53.9 17.5 41.3 35.9 71.1 74.9 43.7 71.0 96.3 34.7 92.8 49.9 3.8 2.3 4.7 0.5 2.3 0.4 1.6 0.6 0.1 2.1 1.0 0.5 0.4 1.2 1.2 0.4 15.7 0.9 0.9 3.5 3.0 5.6 6.6 3.7 3.0 3.4 3.1 3.0 2.4 3.1 4.1 2.3 0.0 3.9 2.0 12.5 9.7 4.6 3.5 6.2 12.1 5.1 3.6 5.7 1.5 2.6 5.5 2.1 25.3 17.3 13.9 1.9 8.5 6.7 5.3 4.2 4.6 1.8 50.3 4.1 6.7 37.9 6.1 10.7 6.5 2.5 19.3 3.3 4.8 12.1 1.7 3.6 10.7 0.0 4.8 21.4 6.7 3.1 11.8 1.8 1.9 11.5 5.2 5.2 2.5 2.9 6.8 1.7 3.8 32.5 4.1 4.6 1.8 5.0 8.4 32.9 5.7 5.5 94.3 103.8 18.7 14.9 14.6 7.7 9.4 14.6 5.9 CHAF1B "CAF-1, CAF1, CAF1A, CAF1P60, MPHOSPH7, MPP7" ENSG00000159259 "Chromatin assembly factor 1 subunit B" Q13112 21 36385392-36419015 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, DNA replication, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 15.6" "Cell type enhanced" "Detected in many" "Spermatocytes: 14.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA021679, CAB033604" Enhanced Supported Nucleoplasm NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB033604: AB_2229411, HPA021679: AB_1846621" "unprognostic (2.28e-2)" "prognostic favorable (5.44e-5)" "prognostic favorable (7.92e-4)" "unprognostic (1.43e-1)" "unprognostic (3.28e-3)" "unprognostic (1.12e-2)" "prognostic unfavorable (6.14e-6)" "unprognostic (2.14e-2)" "unprognostic (1.89e-2)" "unprognostic (1.13e-2)" "unprognostic (2.84e-2)" "unprognostic (6.27e-2)" "unprognostic (7.66e-6)" "unprognostic (5.89e-2)" "unprognostic (5.00e-3)" "unprognostic (9.12e-2)" "unprognostic (1.36e-1)" 1.3 0.6 1.5 2.4 1.2 6.9 2.6 2.2 1.5 1.3 0.3 1.9 1.6 1.7 1.5 2.5 1.3 0.9 0.6 1.6 0.7 1.3 0.7 1.0 3.0 0.6 0.4 1.4 3.3 1.6 1.0 1.1 0.7 1.6 2.1 1.7 3.0 0.9 15.6 2.7 1.9 1.5 0.1 1.3 1.2 4.2 0.8 4.1 0.9 1.8 3.5 1.0 1.5 1.0 25.5 15.0 25.3 14.4 1.9 5.0 13.8 17.6 10.1 21.4 22.2 17.1 13.3 19.9 7.6 9.2 21.7 8.2 26.3 11.7 17.2 20.2 20.5 30.9 15.5 12.2 1.3 19.8 14.4 3.1 2.8 20.0 8.6 4.1 10.2 24.1 27.3 18.0 11.0 17.7 31.0 11.5 17.6 23.0 10.8 45.0 13.6 11.4 7.5 12.4 15.2 12.6 27.0 20.3 9.8 10.1 15.9 13.4 6.3 17.2 8.5 15.4 20.8 13.1 26.0 23.1 11.0 21.5 22.3 1.5 0.2 0.3 1.4 0.1 1.2 1.0 1.0 1.0 0.3 1.1 0.6 1.0 1.2 1.7 0.2 0.4 2.2 0.7 1.5 1.2 2.2 1.5 1.6 0.7 0.6 0.4 0.7 0.1 0.8 1.0 1.3 0.0 2.7 2.0 1.8 2.8 6.2 3.7 5.2 1.6 2.8 3.4 1.3 2.8 3.4 3.7 0.0 7.6 2.5 1.7 0.0 7.3 9.1 2.5 1.2 2.5 0.0 10.7 4.4 2.2 9.7 2.6 4.1 2.4 2.5 9.4 1.4 0.5 4.5 1.7 3.1 2.3 10.2 0.9 1.6 6.7 0.6 1.2 5.4 1.9 1.5 1.5 5.2 1.0 2.5 2.2 0.2 0.0 4.4 4.6 0.4 0.3 3.1 2.6 6.6 3.4 2.5 14.4 11.8 7.4 2.4 2.5 2.4 0.5 4.7 3.4 CHIC2 BTL ENSG00000109220 "Cysteine rich hydrophobic domain 2" Q9UKJ5 4 54009789-54064605 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 348.7;Suprabasal keratinocytes: 373.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 4 "granulocytes: 365.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026782, HPA026784, HPA076603" Uncertain Enhanced "Vesicles,Plasma membrane" NA Yes "Cluster 38: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "Vesicles, Plasma membrane" "HPA026782: AB_1846654, HPA026784: AB_2732433, HPA076603: AB_2732317" "unprognostic (4.56e-2)" "unprognostic (2.24e-3)" "unprognostic (3.47e-3)" "unprognostic (9.58e-2)" "unprognostic (1.49e-1)" "unprognostic (2.25e-2)" "unprognostic (7.87e-2)" "unprognostic (1.22e-1)" "unprognostic (3.65e-2)" "unprognostic (7.81e-3)" "unprognostic (2.94e-2)" "unprognostic (5.63e-2)" "prognostic unfavorable (1.56e-4)" "unprognostic (2.89e-1)" "unprognostic (1.77e-1)" "unprognostic (4.56e-2)" "unprognostic (9.40e-2)" 20.8 15.9 9.1 12.9 8.5 27.1 18.1 12.6 9.6 16.0 12.1 12.4 12.3 12.3 10.3 27.4 12.1 20.5 15.1 8.6 9.2 14.2 20.3 19.7 14.7 8.6 8.5 13.0 9.9 6.5 9.3 13.5 9.0 12.9 8.9 5.9 15.2 5.7 9.8 27.5 13.2 10.5 7.8 17.3 12.9 39.6 9.2 21.9 11.9 6.6 13.3 15.1 18.1 9.7 25.4 4.6 12.8 11.9 21.5 16.8 13.1 34.6 36.1 20.1 20.3 18.1 22.0 21.4 29.5 22.0 17.2 7.7 17.9 25.1 22.0 11.9 9.5 11.7 4.2 13.6 65.1 19.2 23.4 22.6 19.8 30.3 45.3 38.3 30.0 22.2 13.0 15.4 40.6 7.1 22.3 30.7 8.7 11.2 16.9 14.3 7.3 8.4 23.3 8.1 19.7 18.3 8.3 12.2 26.6 18.3 6.1 26.8 51.3 25.2 19.9 36.6 21.4 18.4 9.5 17.2 18.7 18.7 18.7 365.5 79.3 171.5 60.1 64.7 57.7 41.3 60.0 68.6 55.9 40.1 54.6 59.6 325.0 74.2 68.3 47.0 81.5 77.9 9.1 8.5 12.6 9.6 8.6 9.2 8.6 8.5 9.0 7.8 9.2 9.7 58.1 6.4 7.3 35.6 42.5 348.7 95.5 61.0 68.3 8.1 61.6 33.5 4.1 15.7 25.9 7.3 8.4 27.8 57.8 27.2 17.6 42.8 55.4 64.1 58.0 64.3 25.8 72.6 39.7 28.0 38.7 80.8 32.6 34.2 36.3 36.8 38.6 23.9 24.7 13.5 40.2 21.9 40.7 36.4 144.2 13.4 17.1 50.3 67.6 49.6 32.6 9.0 28.8 74.4 23.2 61.8 42.1 24.5 40.2 85.1 41.9 29.2 56.0 7.2 19.7 53.9 45.1 163.5 89.9 97.4 373.8 47.7 65.8 39.8 21.0 135.9 CHKA "CHK, CKI" ENSG00000110721 "Choline kinase alpha" P35790 11 68052859-68121444 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 179.6;Early spermatids: 357.3;Late spermatids: 267.3;Oligodendrocytes: 203.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 6.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "SK-MEL-30: 183.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024153, CAB072803" Approved Approved "Endoplasmic reticulum" NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 34: Spermatids - Unknown function" "Endoplasmic reticulum" "CAB072803: , HPA024153: AB_1846664" "unprognostic (5.16e-2)" "unprognostic (1.46e-1)" "unprognostic (2.52e-1)" "unprognostic (2.51e-1)" "unprognostic (2.66e-1)" "unprognostic (2.81e-1)" "prognostic unfavorable (7.75e-4)" "unprognostic (2.36e-3)" "unprognostic (1.66e-3)" "unprognostic (1.67e-2)" "unprognostic (1.33e-1)" "unprognostic (1.99e-1)" "unprognostic (5.97e-3)" "unprognostic (5.00e-2)" "unprognostic (6.06e-2)" "unprognostic (1.82e-1)" "unprognostic (4.73e-2)" 17.0 35.8 49.4 7.1 54.2 33.8 20.9 51.8 57.8 18.3 53.5 25.8 21.6 12.2 20.5 6.2 13.2 10.3 14.5 49.5 50.7 23.9 43.3 17.8 9.0 56.6 53.6 20.1 38.0 8.0 21.6 5.2 61.5 31.0 12.8 21.1 44.9 16.4 8.3 8.7 23.1 5.4 51.0 30.0 40.0 75.5 54.0 5.7 43.6 4.5 5.5 19.4 9.3 71.7 25.6 21.3 24.2 24.1 8.0 6.1 24.5 7.7 13.6 22.5 14.4 92.2 70.5 18.9 27.4 12.4 23.2 16.2 34.4 5.6 18.5 8.7 12.1 23.8 29.6 106.9 22.9 25.6 12.5 11.0 9.4 10.0 4.8 12.3 12.7 11.9 23.1 34.7 12.0 19.4 14.6 68.4 40.1 83.2 14.2 21.3 26.1 54.6 18.1 27.3 17.9 19.6 14.9 74.6 183.8 19.9 31.6 34.4 7.3 14.2 16.3 32.4 10.4 37.0 42.5 34.4 14.6 32.8 13.0 0.0 0.8 6.1 0.1 1.5 0.0 0.7 0.1 0.2 0.9 0.3 0.4 0.2 0.4 1.1 0.9 0.7 0.2 0.2 49.4 54.2 51.8 57.8 49.5 50.7 56.6 53.6 61.5 51.0 54.0 71.7 27.2 44.8 36.6 179.6 10.1 15.8 16.6 6.5 18.2 10.6 49.4 35.7 3.6 35.8 20.2 3.7 33.3 8.2 14.2 48.1 13.7 9.6 357.3 42.7 16.2 13.6 28.1 6.7 89.0 19.3 3.4 9.2 37.2 59.0 19.0 23.4 11.7 19.8 17.6 57.2 63.2 16.3 0.0 28.5 19.4 267.3 6.2 31.0 23.2 59.0 8.5 21.4 2.1 100.0 203.5 18.4 18.0 2.6 10.1 17.3 21.6 4.6 23.1 28.4 0.0 9.6 9.8 121.9 20.7 9.2 10.4 13.0 8.2 16.9 31.7 39.2 CIP2A KIAA1524 ENSG00000163507 "Cellular inhibitor of PP2A" Q8TCG1 3 108549864-108589644 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.5;lymphoid tissue: 6.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Cytotrophoblasts: 8.0;Exocrine glandular cells: 7.3;Extravillous trophoblasts: 12.9;Granulosa cells: 25.3;Hofbauer cells: 8.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039570 Approved Supported "Plasma membrane,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Plasma membrane" "HPA039570: AB_10796329" "unprognostic (2.02e-1)" "unprognostic (1.54e-2)" "unprognostic (2.31e-3)" "prognostic unfavorable (6.24e-5)" "unprognostic (3.10e-2)" "unprognostic (1.07e-2)" "unprognostic (1.91e-7)" "unprognostic (2.80e-3)" "unprognostic (2.53e-3)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.18e-4)" "unprognostic (6.85e-2)" "prognostic unfavorable (1.42e-4)" "unprognostic (9.11e-3)" "unprognostic (3.73e-1)" "unprognostic (2.11e-1)" "unprognostic (1.25e-1)" 1.1 1.1 0.3 3.4 0.6 7.5 1.4 0.9 0.8 0.9 0.1 1.9 1.2 1.8 0.6 1.7 0.9 1.2 0.7 0.6 0.5 1.0 0.7 1.4 6.7 0.2 0.9 1.9 0.4 0.6 0.7 2.1 0.2 1.8 2.7 2.6 0.6 0.8 0.6 1.2 1.7 1.5 0.0 2.3 1.2 5.7 0.1 6.9 1.2 0.7 5.2 2.0 0.9 0.4 42.2 12.2 33.9 21.8 1.4 3.2 13.8 31.1 14.7 36.2 41.9 15.0 18.5 27.6 10.4 11.4 27.7 20.9 11.7 11.0 65.8 8.8 11.3 33.9 17.4 11.3 0.5 21.8 23.2 1.4 2.3 28.4 11.5 5.9 16.3 12.7 21.1 44.5 36.1 8.7 26.7 19.2 35.0 15.8 20.8 30.1 31.2 15.3 11.0 11.5 16.4 21.6 22.9 9.0 12.7 19.7 15.3 15.6 12.2 37.0 41.7 11.3 38.3 10.2 12.1 46.1 16.4 23.2 38.6 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.6 0.9 0.8 0.6 0.5 0.2 0.9 0.2 0.0 0.1 0.4 1.2 9.6 1.1 0.0 2.3 0.0 0.0 0.0 0.0 0.0 1.9 1.3 0.0 0.0 2.5 3.7 0.0 8.0 1.8 0.0 1.9 2.8 0.0 2.5 2.8 2.6 0.0 0.0 0.0 7.3 12.9 3.0 0.0 2.7 3.8 25.3 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 3.1 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.4 0.0 0.0 2.4 1.5 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 1.4 1.7 5.4 0.0 0.0 CKAP2 "FLJ10749, LB1, se20-10, TMAP" ENSG00000136108 "Cytoskeleton associated protein 2" Q8WWK9 13 52455429-52476628 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 67.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 122.9;Granulosa cells: 88.6;Spermatocytes: 151.7;Spermatogonia: 87.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA008410, HPA027821" Enhanced Enhanced "Microtubules,Mitotic spindle,Centrosome" Yes Yes "Cluster 6: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Microtubules, Mitotic spindle" Centrosome "HPA008410: AB_1846832, HPA027821: AB_10602208" "unprognostic (1.85e-1)" "unprognostic (2.09e-3)" "unprognostic (2.44e-2)" "unprognostic (4.07e-3)" "unprognostic (1.39e-2)" "unprognostic (5.03e-2)" "prognostic unfavorable (3.26e-5)" "unprognostic (3.38e-2)" "unprognostic (4.24e-2)" "unprognostic (1.69e-2)" "unprognostic (8.30e-2)" "unprognostic (6.60e-3)" "prognostic unfavorable (1.90e-5)" "unprognostic (2.01e-2)" "unprognostic (5.20e-2)" "unprognostic (5.97e-2)" "unprognostic (6.36e-2)" 6.0 6.4 3.7 10.0 3.8 67.8 5.7 10.8 5.3 3.2 1.3 8.9 12.1 5.1 4.4 10.4 3.5 4.1 6.0 3.2 4.1 5.1 4.0 5.3 19.4 4.8 3.8 3.2 1.5 4.3 4.5 10.6 5.2 5.6 9.5 7.7 4.6 4.2 2.9 13.9 9.5 8.5 3.3 9.4 5.4 32.5 3.7 33.7 6.3 3.4 20.2 7.2 5.0 3.1 77.6 40.0 155.7 76.4 19.7 19.5 39.6 124.7 70.7 137.4 87.2 59.7 92.3 142.5 19.3 89.2 65.7 86.2 107.6 61.7 188.8 103.0 90.4 129.8 42.6 41.4 8.6 129.7 50.4 14.5 24.6 64.5 83.3 41.2 84.0 62.0 55.3 58.1 152.8 36.0 91.2 64.8 92.2 116.6 42.4 86.2 88.6 62.6 42.1 40.9 47.6 62.4 68.9 49.0 37.1 78.7 54.4 61.7 56.7 38.7 60.9 62.0 124.1 33.4 56.3 173.9 27.3 67.3 105.7 86.0 14.1 22.0 10.3 21.0 9.3 25.3 15.7 12.8 15.8 33.0 12.0 10.4 4.3 5.8 28.7 32.8 33.6 10.0 3.7 3.8 10.8 5.3 3.2 4.1 4.8 3.8 5.2 3.3 3.7 3.1 6.7 6.4 2.8 5.2 41.2 15.0 4.5 32.8 22.2 13.1 11.2 13.2 10.8 2.8 11.4 1.8 6.2 44.3 30.9 7.5 9.8 4.9 41.3 19.4 16.1 12.7 7.2 122.9 10.3 6.0 38.1 12.1 10.7 10.1 16.5 88.6 17.5 5.5 31.8 1.7 12.4 13.6 20.3 24.5 13.7 51.7 7.5 18.5 0.0 6.5 22.9 12.9 5.2 3.5 2.0 2.6 4.6 17.0 30.8 3.7 6.3 9.4 3.7 6.6 6.6 7.6 12.1 151.7 87.5 41.3 15.3 10.0 27.1 29.6 17.9 3.9 CKAP2L "FLJ40629, radmis" ENSG00000169607 "Cytoskeleton associated protein 2 like" Q8IYA6 2 112736349-112764664 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 13.1;lymphoid tissue: 12.1;testis: 4.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 25.2;Granulosa cells: 12.5;Spermatocytes: 33.0;Spermatogonia: 35.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039407, HPA040057, HPA070737" Uncertain Supported "Microtubules,Mitotic spindle,Cytosol" Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Microtubules, Mitotic spindle" Cytosol "HPA039407: AB_10794091, HPA040057: AB_10794871, HPA070737: AB_2686303" "unprognostic (2.29e-1)" "unprognostic (1.54e-1)" "unprognostic (4.69e-3)" "unprognostic (1.42e-3)" "unprognostic (1.69e-1)" "unprognostic (5.59e-2)" "unprognostic (5.75e-5)" "prognostic unfavorable (7.63e-4)" "unprognostic (2.49e-3)" "unprognostic (1.91e-1)" "unprognostic (9.57e-6)" "unprognostic (2.42e-1)" "unprognostic (0.00e+0)" "unprognostic (7.37e-2)" "unprognostic (1.24e-1)" "unprognostic (1.30e-1)" "unprognostic (4.49e-2)" 0.4 0.1 0.2 2.6 0.2 13.1 0.4 0.4 0.3 0.4 0.0 1.6 1.5 0.3 0.1 2.3 0.1 0.3 0.0 0.2 0.1 0.1 0.3 0.3 5.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.1 2.2 0.2 0.3 0.0 0.0 1.5 1.1 1.1 0.0 0.9 1.0 4.5 0.2 12.1 0.2 0.0 5.2 0.8 0.6 0.2 47.9 9.6 35.4 16.2 2.0 3.3 7.2 38.5 32.2 37.9 36.1 8.7 13.3 32.0 15.5 15.1 48.3 18.0 20.4 19.6 64.1 44.8 8.9 53.6 12.7 7.7 0.1 25.2 30.9 0.9 1.9 47.4 27.2 10.1 17.5 22.8 14.3 44.9 31.2 6.9 31.0 10.6 15.4 20.0 29.5 22.3 37.0 8.4 6.9 18.7 19.7 12.7 15.2 12.8 13.3 13.2 12.4 11.8 12.9 42.7 33.7 34.5 28.5 9.9 20.1 26.6 18.5 18.1 69.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.2 0.2 0.4 0.3 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.1 3.2 0.6 0.0 1.2 3.3 2.1 2.7 0.6 0.0 0.5 0.8 0.5 1.5 0.4 0.0 0.0 11.1 1.3 1.3 0.0 0.4 2.4 1.1 1.6 1.1 0.0 25.2 0.3 0.4 10.6 2.0 1.5 2.1 0.0 12.5 2.9 0.1 6.6 0.0 0.2 3.1 2.0 1.9 1.4 2.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.1 0.0 5.6 1.1 0.1 0.1 0.4 0.0 0.0 0.4 2.8 33.0 35.7 9.5 1.7 1.0 2.5 0.7 3.8 1.1 CKAP5 "ch-TOG, KIAA0097, TOG, TOGp" ENSG00000175216 "Cytoskeleton associated protein 5" Q14008 11 46743048-46846308 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 119.7;Spermatocytes: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039377, HPA040375" Supported Approved "Nucleoli,Nucleoli rim,Plasma membrane,Centrosome" NA Yes 360000 "Cluster 27: Non-specific - Gene expression" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Centrosome" "Nucleoli, Nucleoli rim" "HPA039377: AB_10805477, HPA040375: AB_10794739" "unprognostic (8.00e-2)" "unprognostic (7.35e-2)" "unprognostic (2.35e-1)" "unprognostic (4.12e-2)" "unprognostic (1.91e-1)" "unprognostic (2.08e-2)" "prognostic unfavorable (1.03e-6)" "unprognostic (6.09e-2)" "unprognostic (1.12e-2)" "unprognostic (2.21e-2)" "unprognostic (4.30e-3)" "unprognostic (3.77e-2)" "unprognostic (2.03e-1)" "unprognostic (2.71e-1)" "unprognostic (1.12e-1)" "unprognostic (3.48e-1)" "unprognostic (4.69e-2)" 12.8 30.7 15.9 15.1 19.5 25.9 14.9 30.8 24.3 11.7 5.2 18.5 12.6 15.7 12.2 13.0 11.5 12.2 21.3 21.4 18.0 11.5 45.5 10.4 18.4 21.0 17.4 27.8 9.0 21.2 12.5 17.3 22.9 15.9 17.2 57.0 9.1 13.2 37.8 13.7 12.3 19.3 17.5 11.9 16.1 33.0 20.2 36.4 9.6 28.8 18.5 13.5 10.8 24.6 104.7 95.8 212.6 90.8 48.7 73.0 48.3 117.1 69.4 107.8 114.6 76.8 33.3 104.5 41.0 76.0 117.0 116.2 144.0 62.7 134.3 102.0 107.6 176.6 80.2 78.4 35.0 139.6 76.7 37.0 34.0 60.3 125.6 56.1 79.3 97.9 129.5 103.8 89.2 71.2 127.9 39.2 114.7 78.8 73.0 131.2 210.0 98.3 34.7 63.3 96.8 83.9 149.8 56.9 57.3 88.9 103.9 39.1 64.0 106.2 92.9 180.8 176.2 59.2 137.3 158.6 66.5 64.9 105.9 4.6 4.2 4.6 6.1 6.2 5.9 6.5 4.5 6.9 6.1 6.2 5.4 5.8 0.7 8.6 6.2 3.9 5.6 3.1 15.9 19.5 30.8 24.3 21.4 18.0 21.0 17.4 22.9 17.5 20.2 24.6 13.4 25.6 23.6 32.3 17.4 8.5 11.0 17.9 16.5 19.3 11.6 12.3 65.2 12.8 18.8 9.2 37.5 19.4 11.2 13.3 9.8 12.2 119.7 19.7 21.0 16.5 12.1 32.6 61.9 7.8 15.0 27.8 29.0 18.8 37.9 55.5 11.7 8.1 18.7 13.5 63.1 16.9 16.2 17.6 5.6 50.7 19.6 19.6 7.2 30.9 16.5 16.2 16.5 32.6 51.7 13.7 15.2 29.0 26.4 14.2 9.1 9.3 30.7 25.6 19.7 18.0 21.4 107.4 59.3 24.3 11.6 11.5 16.1 83.3 19.8 9.7 CKS1B "CKS1, ckshs1" ENSG00000173207 "CDC28 protein kinase regulatory subunit 1B" P61024 1 154974653-154979251 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 651.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003424, HPA030762" Approved Approved Nucleoplasm,Vesicles,Mitochondria,Cytosol NA Yes "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Mitochondria, Cytosol" "Nucleoplasm, Vesicles" "HPA003424: AB_2666948, HPA030762: AB_10670044" "unprognostic (1.06e-2)" "unprognostic (1.62e-1)" "unprognostic (2.84e-1)" "prognostic unfavorable (7.89e-4)" "unprognostic (1.34e-1)" "unprognostic (2.59e-2)" "prognostic unfavorable (2.94e-5)" "unprognostic (2.01e-3)" "prognostic unfavorable (3.12e-5)" "unprognostic (3.63e-2)" "prognostic unfavorable (6.13e-4)" "unprognostic (3.19e-1)" "prognostic unfavorable (6.03e-7)" "unprognostic (3.12e-2)" "unprognostic (1.44e-1)" "prognostic favorable (4.87e-4)" "unprognostic (1.37e-1)" 59.0 31.9 15.0 33.6 15.8 117.7 67.8 16.4 19.8 44.3 15.0 49.4 40.8 35.0 36.8 61.6 40.9 22.2 35.5 15.4 16.2 37.9 73.3 29.0 71.3 17.5 15.8 31.7 22.4 35.5 18.4 50.6 17.7 26.1 50.5 6.0 28.4 32.9 14.5 51.2 44.3 34.8 17.4 37.0 35.5 48.6 15.7 88.7 30.1 23.5 74.1 30.1 42.6 18.8 459.2 616.5 455.9 245.3 66.9 68.1 361.4 209.1 166.8 463.4 367.8 599.9 653.4 433.8 345.9 143.2 251.2 410.6 468.0 305.2 428.7 392.9 293.9 294.6 249.9 426.5 19.4 359.7 257.9 39.8 132.2 391.4 532.8 91.5 232.5 298.2 486.6 566.8 353.9 452.8 337.3 273.9 575.3 442.1 547.6 334.8 373.6 554.3 165.6 164.2 184.3 463.9 313.6 292.0 347.3 530.2 391.6 492.9 126.0 282.5 292.4 237.0 505.3 348.9 734.7 617.0 179.6 300.1 399.8 2.2 13.0 6.9 19.8 82.0 24.4 74.2 28.0 27.1 22.1 70.4 34.0 32.8 1.7 28.7 105.4 92.6 33.3 28.1 15.0 15.8 16.4 19.8 15.4 16.2 17.5 15.8 17.7 17.4 15.7 18.8 31.7 12.8 33.3 1.3 46.5 217.6 101.3 170.6 74.0 3.4 90.6 140.5 9.2 87.2 63.1 29.5 0.0 224.0 40.7 48.3 80.3 93.0 15.8 43.1 24.6 51.9 20.4 140.1 0.8 112.1 651.8 84.6 20.9 28.3 21.0 66.7 29.6 89.8 132.1 1.7 0.8 57.4 120.1 46.0 121.0 21.7 76.1 37.4 113.8 0.0 41.3 20.7 20.6 0.5 3.5 119.0 41.7 45.9 38.4 130.2 63.1 87.5 52.1 3.0 19.7 50.6 53.0 124.7 151.0 74.9 203.6 131.9 40.7 27.2 80.0 99.5 CKS2 ENSG00000123975 "CDC28 protein kinase regulatory subunit 2" P33552 9 89311195-89316703 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 177.3;testis: 186.3" "Cell type enhanced" "Detected in many" "Langerhans cells: 474.6;Spermatocytes: 692.7;Spermatogonia: 503.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 187.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003424, HPA030762" Approved Approved Nucleoplasm,Vesicles,Mitochondria,Cytosol NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Mitochondria, Cytosol" "Nucleoplasm, Vesicles" "HPA003424: AB_2666948, HPA030762: AB_10670044" "unprognostic (8.30e-2)" "unprognostic (3.00e-1)" "unprognostic (1.50e-2)" "unprognostic (2.80e-2)" "unprognostic (2.96e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (2.51e-6)" "unprognostic (3.57e-3)" "unprognostic (7.04e-2)" "unprognostic (1.34e-2)" "prognostic unfavorable (6.85e-4)" "unprognostic (1.24e-2)" "prognostic unfavorable (1.78e-5)" "unprognostic (2.13e-3)" "unprognostic (1.44e-1)" "unprognostic (2.84e-1)" "unprognostic (1.84e-1)" 13.6 82.9 9.6 38.5 10.0 177.3 20.1 11.9 26.9 10.1 11.8 44.1 43.3 13.0 8.8 53.2 12.1 18.7 10.3 12.7 10.3 35.6 31.2 24.0 102.8 10.5 10.1 9.4 4.2 19.8 4.8 44.3 11.0 15.0 41.0 27.9 10.8 17.8 9.4 19.9 33.1 17.6 10.6 32.6 20.4 186.3 10.8 121.1 12.8 4.8 84.7 26.5 19.9 11.3 685.9 570.1 342.6 230.6 98.7 89.1 249.5 396.1 211.4 428.1 340.0 236.1 328.6 504.9 228.4 149.1 761.4 466.5 415.5 305.1 488.2 398.1 335.5 257.5 378.9 637.5 42.4 531.7 281.2 33.0 69.2 307.2 269.1 162.9 403.2 409.1 313.2 430.6 556.0 509.1 420.7 928.3 501.6 795.5 521.5 358.4 376.4 303.7 342.8 153.5 288.4 171.7 328.7 314.9 324.5 318.4 379.7 304.2 231.4 184.1 350.3 449.6 588.2 345.9 759.2 415.3 271.3 303.1 268.5 40.8 19.5 44.1 22.6 26.5 25.3 61.3 30.4 21.9 22.5 44.7 16.3 21.8 14.5 40.9 14.8 187.9 62.7 23.6 9.6 10.0 11.9 26.9 12.7 10.3 10.5 10.1 11.0 10.6 10.8 11.3 138.6 38.5 103.9 0.3 175.7 280.2 92.1 126.1 259.0 4.1 107.2 169.0 61.3 5.7 49.9 14.7 0.0 231.1 201.1 79.4 23.5 20.1 37.3 149.7 66.4 66.1 122.3 266.9 1.2 11.2 379.4 63.1 74.9 250.2 145.0 144.7 29.3 25.0 184.6 0.0 1.9 164.9 111.9 40.5 474.6 77.0 25.7 164.3 140.5 1.9 31.0 26.1 28.8 1.0 1.1 31.1 67.1 16.6 89.3 72.1 37.6 209.7 32.8 7.3 46.0 75.2 206.5 692.7 503.6 197.5 299.1 199.5 156.0 70.3 162.7 102.1 CLSPN ENSG00000092853 Claspin Q9HAW4 1 35720218-35769978 "Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.3;lymphoid tissue: 7.9;retina: 6.8;testis: 5.7" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 101.0;Spermatocytes: 281.1;Spermatogonia: 263.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Region enriched" "Detected in some" 6 "basal ganglia: 7.8" "Low region specificity" "Detected in many" "HPA026305, HPA026312" Enhanced "Nucleoplasm,Golgi apparatus" Yes Yes "Cluster 17: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Golgi apparatus" "HPA026305: AB_2671833, HPA026312: AB_2671837" "unprognostic (4.75e-2)" "unprognostic (1.01e-1)" "unprognostic (9.64e-3)" "unprognostic (3.54e-2)" "unprognostic (6.82e-2)" "unprognostic (1.62e-2)" "unprognostic (1.18e-6)" "unprognostic (3.99e-3)" "unprognostic (2.08e-3)" "unprognostic (1.63e-2)" "unprognostic (8.71e-6)" "unprognostic (3.23e-2)" "unprognostic (7.61e-6)" "prognostic favorable (4.92e-4)" "unprognostic (5.12e-1)" "unprognostic (1.73e-1)" "unprognostic (1.29e-1)" 0.5 0.2 0.7 3.2 0.6 11.3 0.5 0.6 1.4 0.2 0.4 1.4 1.0 0.4 0.7 0.9 0.2 0.3 0.1 1.3 0.3 0.2 0.5 0.4 4.9 0.4 0.4 0.1 0.1 0.2 0.0 1.5 0.6 0.2 2.0 6.8 0.2 0.1 0.6 1.2 1.0 0.9 0.2 1.3 0.9 5.7 0.6 7.9 0.2 0.0 5.2 0.6 0.4 0.9 22.0 17.5 37.8 19.9 2.6 4.8 14.1 43.6 12.0 31.0 41.3 27.9 19.6 45.7 13.9 11.8 22.7 21.4 37.1 14.9 48.1 31.6 16.8 64.5 38.1 12.6 0.1 54.0 36.8 1.0 0.6 53.8 3.7 3.7 16.9 27.1 44.2 30.8 30.3 14.1 56.9 13.1 36.0 14.9 12.2 36.0 57.0 13.8 6.4 35.3 14.0 16.2 37.7 11.6 7.4 25.6 10.0 21.1 12.5 44.6 33.8 27.6 49.3 11.1 29.1 47.1 14.1 37.4 37.0 1.1 0.3 0.3 0.3 0.2 0.1 0.1 0.2 0.2 0.2 0.3 0.1 0.2 1.0 0.5 0.2 0.2 0.3 0.3 0.7 0.6 0.6 1.4 1.3 0.3 0.4 0.4 0.6 0.2 0.6 0.9 2.6 0.0 0.5 0.3 6.5 5.6 5.7 4.4 1.2 9.4 2.9 3.8 1.4 2.8 2.7 0.0 12.5 19.7 4.6 12.8 0.0 1.6 7.9 1.0 3.6 3.6 1.2 55.6 1.6 0.6 41.1 5.2 4.6 3.3 1.3 12.0 2.2 0.4 16.9 1.7 1.5 9.4 2.0 3.0 8.2 6.1 2.5 5.8 3.6 0.0 9.1 9.4 4.1 0.0 0.6 1.4 9.5 0.4 32.5 1.8 0.4 0.2 0.0 101.0 6.6 5.3 8.7 281.1 263.3 5.8 2.0 10.4 7.2 1.2 12.0 3.9 CMC2 "C16orf61, DC13, MGC45036" ENSG00000103121 "C-X9-C motif containing 2" Q9NRP2 16 80966448-81020270 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 263.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA006871, CAB026396" Approved Supported Mitochondria NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB026396: , HPA006871: AB_1845581" "unprognostic (2.43e-1)" "unprognostic (3.63e-2)" "unprognostic (1.70e-1)" "unprognostic (3.52e-2)" "unprognostic (1.50e-1)" "unprognostic (3.01e-3)" "unprognostic (2.48e-2)" "unprognostic (6.36e-2)" "unprognostic (9.20e-2)" "unprognostic (3.84e-3)" "unprognostic (3.48e-2)" "unprognostic (4.57e-3)" "prognostic favorable (2.64e-5)" "unprognostic (1.08e-1)" "unprognostic (1.51e-1)" "unprognostic (1.17e-1)" "unprognostic (2.68e-1)" 22.1 24.6 47.6 14.0 50.0 45.2 17.0 49.0 60.2 17.2 41.2 22.7 19.1 12.4 16.6 20.4 11.6 17.0 68.4 48.4 50.7 43.5 44.0 24.3 22.4 47.6 47.6 13.7 27.3 30.4 26.1 16.3 47.5 34.9 16.9 16.1 14.8 12.4 54.0 15.3 20.3 15.0 48.3 21.7 27.2 47.0 51.2 30.1 16.2 33.9 17.1 20.7 17.0 54.2 74.8 103.1 76.1 43.7 25.1 25.0 44.9 73.4 33.1 64.0 32.9 71.7 49.9 33.5 53.3 35.8 62.9 52.6 52.5 42.8 84.9 50.9 63.3 51.9 68.4 78.6 40.6 43.5 85.4 21.8 23.8 77.7 43.5 29.2 57.1 83.1 124.2 43.5 63.3 140.1 68.1 138.4 45.2 59.7 62.0 84.2 41.2 43.8 50.4 35.9 64.1 37.1 110.6 39.8 87.3 39.4 78.7 39.2 32.8 57.9 82.0 56.6 75.3 45.4 107.6 193.8 44.6 55.3 69.1 33.2 28.0 37.3 28.8 29.6 27.5 39.1 36.5 30.1 31.6 34.9 25.3 29.2 12.0 44.6 34.2 45.3 64.4 18.0 47.6 50.0 49.0 60.2 48.4 50.7 47.6 47.6 47.5 48.3 51.2 54.2 41.2 35.3 38.8 48.0 54.9 97.6 75.5 53.9 48.9 31.9 48.0 50.7 204.7 42.9 36.5 47.8 54.2 44.8 78.9 29.5 158.5 34.4 95.4 44.2 33.7 36.0 38.3 55.5 88.6 38.0 62.8 45.0 42.8 45.2 95.5 37.3 25.4 86.0 51.4 30.3 62.2 42.9 59.0 70.5 84.1 168.3 24.5 59.7 65.8 14.0 33.8 29.3 51.5 48.7 74.0 39.0 31.9 29.3 83.5 69.1 48.5 166.1 31.4 16.7 59.2 33.3 47.0 263.5 121.5 65.0 102.1 38.0 84.7 55.3 44.8 74.4 CNTRL "CEP1, CEP110" ENSG00000119397 Centriolin Q7Z7A1 9 121074753-121177610 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 28.0;testis: 35.3" "Cell type enhanced" "Detected in many" "Early spermatids: 131.7;Spermatocytes: 385.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HL-60: 81.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020468, HPA020480, HPA051583" Approved Approved "Centriolar satellite,Centrosome,Cytosol" NA Yes "Cluster 6: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Centrosome, Cytosol" "Centriolar satellite" "HPA020468: AB_2670455, HPA020480: AB_2670457, HPA051583: AB_2681542" "unprognostic (4.33e-3)" "unprognostic (2.89e-3)" "unprognostic (2.09e-2)" "unprognostic (7.97e-2)" "unprognostic (1.17e-2)" "prognostic favorable (9.21e-5)" "unprognostic (1.05e-2)" "unprognostic (3.22e-3)" "unprognostic (3.74e-3)" "unprognostic (2.02e-1)" "unprognostic (1.78e-2)" "unprognostic (5.47e-2)" "unprognostic (3.60e-3)" "unprognostic (9.83e-3)" "unprognostic (2.43e-1)" "unprognostic (3.57e-2)" "unprognostic (1.13e-2)" 5.3 3.7 2.5 13.8 3.6 28.0 5.0 4.0 3.2 4.4 6.9 4.6 4.0 6.7 2.7 4.1 7.8 5.4 2.8 2.1 3.3 2.8 4.1 6.7 23.3 5.4 5.5 7.5 3.9 2.8 3.1 6.3 4.1 4.5 5.6 7.5 3.6 3.8 1.1 4.9 5.2 4.9 3.7 12.6 7.8 35.3 3.4 23.9 4.8 1.8 21.7 6.5 2.8 5.3 12.6 8.3 22.5 16.4 3.3 4.9 4.2 8.4 6.2 6.6 5.6 4.7 13.2 55.7 3.3 6.3 11.8 25.2 7.6 5.2 10.4 34.3 5.5 29.4 15.2 6.1 4.5 81.0 34.1 3.1 3.8 6.9 16.5 2.8 14.6 22.7 19.2 31.0 6.5 7.9 31.2 21.5 8.1 16.0 6.6 30.1 33.4 17.4 3.1 5.7 8.5 12.9 28.4 5.2 6.3 3.9 11.0 36.0 10.3 6.7 11.6 10.8 15.8 22.0 25.6 37.8 5.6 32.2 16.1 16.2 7.0 17.0 7.2 4.3 5.5 11.7 7.5 5.5 3.7 11.9 9.0 6.4 2.7 5.0 6.5 10.6 11.5 2.8 2.5 3.6 4.0 3.2 2.1 3.3 5.4 5.5 4.1 3.7 3.4 5.3 19.8 28.9 32.8 34.9 78.7 3.3 13.8 6.8 9.1 33.5 7.4 12.2 8.9 10.0 29.5 3.7 37.5 2.7 58.2 2.7 3.9 5.1 131.7 61.8 12.3 14.8 8.4 33.2 35.4 6.0 3.0 15.1 14.8 10.9 53.0 20.6 14.6 3.9 27.2 30.3 43.8 8.4 4.1 33.9 16.5 44.3 13.7 50.7 8.8 52.5 55.2 8.2 49.4 37.2 53.1 6.3 4.5 12.0 39.1 4.3 2.2 1.4 114.6 59.6 39.5 33.8 14.5 385.0 114.1 10.9 5.7 0.8 57.0 13.1 6.4 6.2 CPA4 CPA3 ENSG00000128510 "Carboxypeptidase A4" Q9UI42 7 130293134-130324180 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 21.6;skin 1: 57.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 17.7;Basal respiratory cells: 23.7;Exocrine glandular cells: 54.1;Fibroblasts: 11.5;Suprabasal keratinocytes: 31.0" "Cancer enhanced" "Detected in many" "cervical cancer: 10.0;head and neck cancer: 9.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 140.1;hTERT-RPE1: 261.0;LHCN-M2: 284.2;U-2 OS: 151.0;U-87 MG: 272.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA021030 Approved Nucleoplasm,Centrosome,Cytosol "Secreted in other tissues" NA Yes 390000 "Cluster 31: Skin - Epidermis development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "Centrosome, Cytosol" "HPA021030: AB_1846010" "unprognostic (7.60e-3)" "unprognostic (4.00e-2)" "unprognostic (1.59e-3)" "unprognostic (3.63e-3)" "unprognostic (2.24e-2)" "unprognostic (2.91e-2)" "unprognostic (2.78e-2)" "unprognostic (4.36e-3)" "unprognostic (3.23e-1)" "unprognostic (5.79e-2)" "unprognostic (2.37e-3)" "unprognostic (6.49e-2)" "unprognostic (6.21e-10)" "unprognostic (2.39e-1)" "unprognostic (1.67e-1)" "unprognostic (7.56e-2)" "prognostic unfavorable (1.31e-4)" 5.0 4.4 0.4 0.4 0.4 0.1 3.5 0.5 1.7 15.3 0.5 0.0 0.0 0.2 0.3 21.6 0.4 0.1 1.1 0.6 2.1 0.6 0.1 0.4 0.2 1.1 0.7 0.1 12.7 0.0 0.5 2.0 1.1 0.2 0.0 0.2 6.7 0.0 0.3 57.1 0.2 0.8 0.6 3.3 0.4 0.3 1.2 0.8 0.0 0.0 0.9 0.0 12.6 1.1 95.3 5.0 0.3 0.3 0.7 1.5 0.1 74.6 140.1 74.9 18.5 0.7 8.1 0.1 14.3 31.9 75.2 5.5 0.0 41.3 76.7 0.4 0.3 0.0 33.3 2.1 1.8 0.3 0.2 1.0 65.2 6.7 9.4 261.0 0.3 0.1 0.0 0.2 284.2 0.2 0.0 0.0 0.8 0.4 11.1 0.3 75.4 0.1 34.5 4.0 0.2 0.0 49.9 23.3 0.5 28.0 0.5 0.4 57.3 18.1 151.0 6.2 7.4 0.2 0.2 0.1 272.7 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.4 0.5 1.7 0.6 2.1 1.1 0.7 1.1 0.6 1.2 1.1 0.0 3.2 0.5 0.0 0.0 17.7 0.5 23.7 0.6 0.0 4.2 2.8 0.3 0.0 8.5 0.0 0.0 5.6 0.1 0.0 0.0 0.5 0.4 0.4 0.2 0.3 0.0 0.0 0.4 54.1 1.2 11.5 0.0 2.0 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.2 0.2 0.0 0.3 3.6 1.0 0.6 0.0 0.0 0.0 0.5 7.9 0.0 0.0 0.0 0.9 0.0 0.1 2.9 0.0 0.0 1.3 0.4 0.1 0.7 10.0 31.0 9.4 0.1 0.0 0.0 1.6 CREB5 "CRE-BPA, H_GS165L15.1" ENSG00000146592 "CAMP responsive element binding protein 5" Q02930 7 28299321-28825894 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.0" "Cell type enhanced" "Detected in many" "Adipocytes: 165.7;Basal prostatic cells: 192.2;monocytes: 163.9;Oligodendrocyte precursor cells: 229.7;Oligodendrocytes: 734.9" "Cancer enhanced" "Detected in many" "renal cancer: 5.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 198.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 198.8" "Cell line enhanced" "Detected in many" "HL-60: 62.5;Karpas-707: 25.0;U-2 OS: 25.7;U-2197: 28.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA050020, HPA061622" Approved "Nucleoplasm,Vesicles,Plasma membrane" NA Yes "Cluster 50: Neutrophils - Cellular senescence" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Vesicles, Plasma membrane" "HPA050020: AB_2680993, HPA061622: AB_2684569" "unprognostic (3.59e-2)" "unprognostic (3.80e-1)" "unprognostic (1.06e-1)" "unprognostic (6.46e-2)" "unprognostic (1.01e-1)" "unprognostic (4.90e-3)" "unprognostic (2.01e-3)" "unprognostic (2.87e-1)" "unprognostic (3.31e-1)" "unprognostic (1.04e-1)" "unprognostic (3.49e-1)" "unprognostic (2.67e-1)" "unprognostic (4.91e-3)" "unprognostic (6.61e-2)" "unprognostic (3.95e-1)" "unprognostic (1.60e-1)" "unprognostic (1.52e-3)" 10.5 1.3 6.3 7.9 20.5 6.1 5.0 6.8 12.7 1.7 0.0 3.5 0.9 8.4 2.8 3.5 2.2 11.4 5.3 9.6 19.9 3.0 1.8 6.1 0.9 19.7 14.6 0.7 3.2 0.2 1.1 3.7 15.8 1.2 1.7 1.3 3.5 1.0 3.2 2.9 2.2 4.7 2.9 7.4 1.4 0.7 23.0 0.7 1.8 4.0 0.8 4.4 2.2 35.0 0.1 0.6 7.3 0.4 0.4 10.3 0.3 0.7 1.6 4.4 6.6 4.2 2.7 18.9 1.3 1.8 4.5 0.7 0.2 6.4 13.8 0.0 5.0 20.4 4.2 0.4 0.4 62.5 0.7 1.3 1.2 18.9 20.1 0.9 3.0 0.1 2.4 25.0 1.5 0.1 0.1 0.0 9.1 0.1 7.4 0.5 6.8 0.5 9.0 2.0 0.7 5.2 0.3 0.4 2.2 10.0 0.2 1.5 0.8 8.6 25.7 28.7 8.5 1.5 4.5 0.2 9.4 0.3 14.8 0.1 29.9 0.0 0.0 9.7 0.0 1.9 0.0 0.0 18.2 0.1 0.0 0.0 198.8 0.0 3.9 0.3 0.0 7.0 6.3 20.5 6.8 12.7 9.6 19.9 19.7 14.6 15.8 2.9 23.0 35.0 165.7 6.4 7.2 10.7 3.2 21.9 192.2 8.2 13.1 1.3 10.7 8.9 16.8 17.2 6.3 12.9 0.0 4.0 0.8 0.0 1.9 74.2 0.4 41.0 56.3 31.3 0.0 0.4 17.0 27.4 13.4 108.0 3.1 69.7 14.0 0.6 14.3 0.5 8.3 5.0 22.2 0.0 6.1 47.4 118.2 1.6 5.9 75.8 30.2 22.5 163.9 14.3 4.1 229.7 734.9 22.5 0.0 0.4 3.2 44.9 0.0 25.6 4.7 0.9 19.7 143.5 31.8 12.6 7.3 12.0 13.2 24.8 3.1 2.6 0.0 35.1 CSE1L "CAS, CSE1, XPO2" ENSG00000124207 "Chromosome segregation 1 like" P55060 20 49046246-49096960 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 164.0;Spermatogonia: 121.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002140, HPA038059, HPA038060" Enhanced Enhanced Nucleoplasm,Cytosol No Yes 320000 "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 39: CACO-2 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "CAB002140: AB_563461, HPA038059: AB_2675811, HPA038060: AB_2675812" "unprognostic (4.01e-2)" "unprognostic (3.15e-2)" "unprognostic (5.63e-2)" "prognostic unfavorable (2.91e-5)" "unprognostic (4.86e-1)" "unprognostic (4.91e-2)" "prognostic unfavorable (2.42e-8)" "unprognostic (3.44e-2)" "unprognostic (1.45e-2)" "unprognostic (2.63e-2)" "unprognostic (2.72e-3)" "unprognostic (2.54e-2)" "prognostic unfavorable (1.89e-4)" "unprognostic (2.59e-1)" "unprognostic (4.84e-1)" "unprognostic (5.71e-1)" "prognostic unfavorable (6.91e-4)" 23.6 24.5 16.0 29.0 20.2 26.4 34.2 26.6 21.1 25.7 12.9 23.6 19.8 28.1 23.8 38.2 27.0 19.0 24.7 17.1 18.0 29.8 30.9 19.7 35.0 21.0 17.3 27.2 20.4 30.8 13.6 37.5 22.8 25.8 28.7 23.2 21.7 25.6 39.8 34.4 19.2 35.0 21.1 20.3 20.7 87.7 17.0 40.7 23.4 41.5 42.8 27.5 22.2 29.1 224.3 152.4 182.1 140.9 69.0 88.5 196.7 172.1 90.5 528.1 222.0 501.8 175.4 227.3 224.1 109.7 213.9 251.4 270.7 322.9 500.0 37.4 131.3 158.0 166.1 244.7 42.0 176.2 83.3 50.0 118.7 259.0 148.7 72.4 177.5 124.3 227.2 87.1 201.1 76.8 213.9 90.6 153.5 185.1 224.0 133.9 299.5 176.4 116.5 153.2 159.6 92.6 275.2 293.3 97.1 137.7 245.3 113.3 115.5 279.3 233.9 166.4 247.9 50.5 130.8 210.8 166.8 139.5 152.2 18.6 16.3 3.8 13.8 20.6 21.1 16.7 21.0 17.1 20.1 13.6 22.1 19.3 4.4 23.0 23.6 8.9 20.1 18.3 16.0 20.2 26.6 21.1 17.1 18.0 21.0 17.3 22.8 21.1 17.0 29.1 16.4 6.4 26.8 8.1 20.3 30.2 25.8 29.5 31.3 14.9 17.4 15.9 26.6 24.3 22.4 27.6 10.4 71.8 15.7 7.4 13.7 32.2 95.9 14.7 19.4 22.9 5.4 40.4 20.9 26.6 61.2 24.6 13.7 17.8 4.5 35.1 19.2 26.7 29.7 15.2 24.4 11.8 20.3 17.9 21.9 57.8 25.4 17.9 26.6 9.4 28.0 22.6 7.2 17.1 41.7 26.7 10.0 31.6 26.7 28.8 9.9 21.6 21.7 15.5 39.5 19.3 22.1 164.0 121.5 36.7 34.5 72.7 17.5 31.1 23.7 22.2 CSKMT "CS-KMT, METTL12, U99HG" ENSG00000214756 "Citrate synthase lysine methyltransferase" A8MUP2 11 62665309-62668496 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Adipocytes: 40.4;Alveolar cells type 2: 41.4;Breast glandular cells: 65.9;Breast myoepithelial cells: 68.5;dendritic cells: 46.3;Endometrial stromal cells: 37.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in some" "Low region specificity" "Detected in all" HPA038533 Approved NA Yes "Cluster 30: Non-specific - Translation" "Cluster 6: T47d - Mammary gland" "Cluster 7: Non-specific - Mitochondria" "HPA038533: AB_10697392" "prognostic favorable (8.73e-4)" "unprognostic (2.59e-1)" "unprognostic (3.84e-1)" "unprognostic (1.15e-1)" "unprognostic (1.48e-2)" "unprognostic (3.17e-1)" "unprognostic (9.43e-5)" "unprognostic (1.55e-2)" "unprognostic (7.62e-2)" "unprognostic (2.88e-1)" "unprognostic (1.07e-1)" "unprognostic (2.54e-1)" "unprognostic (4.98e-3)" "unprognostic (2.72e-3)" "unprognostic (1.85e-1)" "unprognostic (1.57e-2)" "unprognostic (3.28e-1)" 0.3 0.3 0.4 0.1 0.3 0.1 0.4 0.3 0.7 0.5 0.3 0.4 0.5 0.4 0.1 0.5 0.5 0.1 0.3 0.3 0.4 0.3 0.3 0.2 0.2 0.4 0.3 0.6 0.7 0.1 0.2 0.5 0.4 0.4 0.4 0.1 0.3 0.4 0.9 0.3 0.2 0.1 0.3 0.2 0.4 0.0 0.4 0.2 0.2 0.2 0.3 0.4 0.5 0.4 0.9 0.9 0.3 0.4 2.6 1.0 0.4 0.3 0.6 0.7 0.9 0.7 0.9 1.6 0.4 1.2 0.2 1.7 1.6 0.8 1.4 0.5 0.0 0.6 0.0 1.0 0.0 0.0 0.6 0.9 2.7 0.2 1.0 0.7 0.2 0.2 0.7 0.0 1.0 0.8 0.5 0.7 1.6 0.0 0.8 0.8 0.4 0.2 0.3 0.1 0.0 0.0 0.8 1.0 0.9 0.4 2.0 0.2 0.0 0.2 0.9 2.4 0.0 0.3 0.0 0.0 0.2 0.4 0.4 0.7 1.1 0.1 0.8 1.8 1.7 2.9 2.4 1.1 1.1 1.5 2.9 2.5 0.0 0.5 1.3 1.3 1.3 1.4 0.4 0.3 0.3 0.7 0.3 0.4 0.4 0.3 0.4 0.3 0.4 0.4 40.4 12.8 41.4 0.0 25.0 0.0 0.0 0.0 0.0 0.0 65.9 68.5 0.0 0.0 21.1 18.4 0.0 27.7 46.3 0.0 5.9 7.4 0.0 17.5 37.7 10.1 0.0 0.0 0.0 5.6 20.0 13.2 0.0 23.0 27.8 15.3 0.0 0.0 19.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 0.0 0.0 2.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 8.8 0.0 0.0 9.8 6.6 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.0 26.5 24.4 13.5 0.0 0.0 CTPS1 "CTPS, GATD5" ENSG00000171793 "CTP synthase 1" P17812 1 40979688-41012565 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Pyrimidine biosynthesis" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 73.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017111, HPA051322" Enhanced Approved "Actin filaments,Cytosol" NA Yes 150000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Cytosol "Actin filaments" "CAB017111: , HPA051322: AB_2681441" "unprognostic (6.60e-2)" "unprognostic (4.44e-2)" "unprognostic (3.21e-2)" "unprognostic (2.00e-3)" "unprognostic (2.14e-1)" "unprognostic (8.37e-2)" "unprognostic (1.42e-2)" "unprognostic (9.72e-3)" "unprognostic (1.94e-3)" "unprognostic (1.01e-1)" "unprognostic (2.04e-2)" "unprognostic (8.93e-3)" "unprognostic (1.09e-1)" "unprognostic (8.21e-3)" "unprognostic (1.34e-1)" "unprognostic (4.49e-1)" "unprognostic (1.89e-2)" 9.1 8.1 4.8 11.1 4.7 6.8 6.7 4.0 5.8 9.3 7.9 8.7 4.4 23.6 5.7 14.9 11.1 10.6 5.3 4.9 5.3 12.4 73.4 7.6 12.4 4.6 4.9 3.4 4.7 47.6 0.0 7.8 5.8 13.5 12.0 2.4 50.6 24.8 7.7 4.6 8.4 51.9 4.7 5.0 4.1 14.7 4.9 17.3 4.8 7.6 17.8 17.7 0.3 5.0 77.8 68.5 95.3 60.5 22.9 30.9 138.5 138.8 57.0 141.2 92.0 131.5 66.6 149.8 55.6 61.7 39.4 38.6 91.5 97.0 139.5 66.5 78.0 87.3 72.3 43.3 87.8 128.0 56.8 34.0 49.2 148.5 103.0 23.0 64.1 102.2 84.7 51.5 99.4 42.9 125.0 38.1 126.8 66.4 81.3 100.9 120.0 93.7 71.4 69.4 118.4 61.7 79.2 77.7 33.9 90.8 30.1 152.9 53.5 78.2 119.6 61.7 167.2 36.8 50.8 134.5 59.8 84.5 97.4 0.0 3.5 0.0 3.6 6.5 5.7 5.2 4.1 4.3 11.0 4.0 3.7 6.1 0.0 6.9 5.9 11.9 6.3 3.4 4.8 4.7 4.0 5.8 4.9 5.3 4.6 4.9 5.8 4.7 4.9 5.0 5.4 6.4 18.4 4.9 10.9 8.0 14.3 9.1 9.6 12.5 4.6 4.7 5.7 21.5 7.0 5.5 6.2 15.4 26.4 2.2 1.9 19.2 32.4 4.7 10.8 8.5 3.0 22.5 14.1 17.2 26.4 8.7 7.1 7.3 1.3 15.8 2.2 29.0 11.0 11.8 18.7 3.4 6.1 2.8 6.2 27.9 10.8 6.8 1.8 7.5 8.7 5.4 7.2 7.1 10.3 19.3 1.1 24.8 15.1 19.3 25.2 12.8 2.8 4.3 39.5 9.3 17.5 11.1 40.6 11.8 7.4 5.6 9.9 20.7 5.8 7.3 CYP24A1 "CP24, CYP24, P450-CC24" ENSG00000019186 "Cytochrome P450 family 24 subfamily A member 1" Q07973 20 54153446-54173986 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "endometrium 1: 14.9;kidney: 35.3;lymphoid tissue: 10.5;placenta: 10.0;urinary bladder: 28.7" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 48.3;Basal respiratory cells: 142.7;Basal squamous epithelial cells: 74.0;Club cells: 47.0;Proximal tubular cells: 61.3;Urothelial cells: 36.7" "Cancer enhanced" "Detected in many" "lung cancer: 18.3;urothelial cancer: 21.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "A549: 411.5;Hep G2: 122.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA022261, HPA063771" Enhanced Approved "Nucleoplasm,Plasma membrane,Mitochondria" NA Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 7: Kidney - Transmembrane transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Mitochondria" "Plasma membrane" "HPA022261: AB_1847427, HPA063771: AB_2685120" "unprognostic (1.19e-7)" "unprognostic (1.73e-1)" "unprognostic (2.24e-2)" "unprognostic (7.69e-3)" "unprognostic (3.30e-1)" "unprognostic (2.30e-2)" "unprognostic (1.11e-2)" "unprognostic (2.12e-1)" "unprognostic (2.09e-2)" "unprognostic (5.37e-3)" "unprognostic (1.23e-1)" "unprognostic (6.05e-2)" "unprognostic (5.98e-2)" "unprognostic (1.36e-1)" "unprognostic (4.38e-2)" "unprognostic (2.12e-1)" 0.0 0.0 0.2 0.4 0.4 0.0 3.7 0.0 0.3 1.7 0.0 0.0 0.1 14.9 0.2 3.8 0.2 0.0 0.0 0.1 1.8 35.3 0.4 0.7 0.2 0.4 2.0 0.0 0.0 0.0 0.2 10.0 0.3 2.9 0.0 0.0 0.3 2.0 0.0 0.9 0.0 0.2 0.1 0.0 0.0 0.0 0.6 0.2 1.3 0.0 10.5 28.7 1.3 0.2 0.5 411.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 12.6 0.0 3.2 0.0 0.9 15.8 0.0 0.1 0.1 0.0 0.0 0.0 6.5 122.6 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.7 0.0 7.0 1.3 0.0 2.6 0.6 0.0 0.1 0.1 0.0 0.0 0.0 16.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.3 0.1 1.8 0.4 2.0 0.3 0.1 0.6 0.2 0.0 0.0 0.0 0.0 1.3 22.8 48.3 142.7 74.0 0.0 11.0 8.6 0.4 0.0 47.0 0.0 0.0 0.1 0.1 0.1 5.9 0.1 0.0 0.7 0.5 0.3 0.0 0.0 0.2 0.0 0.1 2.0 0.0 4.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 9.8 0.0 61.3 13.1 0.0 0.0 0.0 0.6 0.0 0.0 3.3 19.6 0.1 0.1 0.0 0.2 36.7 DBF4 "ASK, chif, DBF4A, ZDBF1" ENSG00000006634 "DBF4 zinc finger" Q9UBU7 7 87876216-87909553 "Predicted intracellular proteins" "Cell cycle, DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 20 "testis: 15.1" "Group enriched" "Detected in all" 4 "Early spermatids: 468.6;Spermatocytes: 569.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042923 Supported "Nucleoplasm,Nuclear bodies" Yes Yes "Cluster 10: Basophils - Unknown function" "Cluster 74: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "HPA042923: AB_2678222" "unprognostic (2.48e-1)" "unprognostic (8.32e-2)" "unprognostic (1.15e-2)" "unprognostic (4.86e-3)" "unprognostic (2.81e-2)" "unprognostic (3.63e-1)" "prognostic unfavorable (4.45e-6)" "unprognostic (1.05e-1)" "prognostic unfavorable (6.86e-4)" "unprognostic (1.46e-3)" "unprognostic (1.05e-3)" "unprognostic (2.78e-3)" "prognostic unfavorable (6.42e-7)" "unprognostic (1.98e-2)" "unprognostic (2.40e-1)" "unprognostic (1.47e-1)" "unprognostic (1.30e-1)" 0.1 0.2 0.2 0.2 0.4 0.6 0.2 0.7 0.4 0.2 0.1 0.2 0.2 0.2 0.3 0.1 0.1 0.4 0.1 0.2 0.1 0.2 0.2 0.1 0.5 0.2 0.2 0.2 0.1 0.1 0.0 0.1 0.2 0.2 0.2 0.2 0.1 0.1 0.1 0.2 0.3 0.0 0.1 0.3 0.2 15.1 0.2 0.6 0.3 0.0 0.5 0.1 0.1 0.3 0.9 0.8 2.0 2.5 0.4 0.4 0.5 1.0 0.2 1.0 2.1 1.4 0.6 2.1 0.6 0.6 1.7 0.9 2.2 0.5 1.0 1.6 1.3 1.3 1.0 0.4 0.1 1.7 1.0 0.4 0.6 1.2 1.0 0.3 0.9 1.9 1.2 4.2 1.4 1.7 2.8 2.0 2.0 2.1 1.9 0.7 3.1 2.5 0.8 0.1 3.0 1.8 1.2 2.2 1.0 1.6 0.9 1.6 0.1 1.2 1.4 3.1 2.0 2.3 5.2 2.1 0.8 3.1 2.5 1.0 0.1 0.1 0.3 0.0 0.1 0.2 0.2 0.1 0.0 0.2 0.2 0.3 0.2 0.2 0.0 0.2 0.4 0.1 0.2 0.4 0.7 0.4 0.2 0.1 0.2 0.2 0.2 0.1 0.2 0.3 13.3 3.2 12.6 5.5 38.4 15.6 16.4 10.7 12.0 6.6 13.0 16.8 3.7 2.8 7.7 9.2 12.5 19.6 59.2 9.7 3.9 8.3 468.6 12.1 23.6 11.1 14.9 40.8 14.7 14.7 36.4 12.4 14.3 17.7 31.0 19.4 6.4 6.5 16.1 3.3 9.1 20.6 16.2 9.1 15.5 116.0 15.5 20.8 12.4 2.8 11.0 2.1 24.7 6.0 6.7 14.1 8.5 9.4 48.9 18.4 4.2 5.8 10.2 16.6 13.1 9.7 11.4 569.4 74.6 20.5 12.6 9.6 44.4 13.5 22.3 11.7 DBF4B "ASKL1, chifb, DRF1, FLJ13087, ZDBF1B" ENSG00000161692 "DBF4 zinc finger B" Q8NFT6 17 44708608-44752264 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 30.0;Horizontal cells: 30.3;Oligodendrocytes: 30.9;Spermatocytes: 35.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA048465, HPA077959" Approved Supported Nucleoplasm,Vesicles NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm Vesicles "HPA048465: AB_2680405, HPA077959: " "unprognostic (2.44e-1)" "unprognostic (1.26e-1)" "unprognostic (6.37e-2)" "unprognostic (2.15e-3)" "unprognostic (1.62e-1)" "unprognostic (6.13e-2)" "unprognostic (1.53e-4)" "unprognostic (7.61e-2)" "unprognostic (1.54e-2)" "unprognostic (4.08e-2)" "unprognostic (8.43e-3)" "unprognostic (1.83e-1)" "unprognostic (4.23e-6)" "unprognostic (1.50e-1)" "unprognostic (3.36e-1)" "unprognostic (2.57e-1)" "unprognostic (1.39e-1)" 0.9 0.7 1.1 1.2 1.1 2.0 1.3 1.2 1.8 1.5 0.5 1.9 0.6 1.9 3.5 1.4 1.8 0.7 0.8 1.1 1.0 1.6 0.6 0.8 1.5 1.1 1.0 1.7 0.9 0.8 1.7 0.9 1.1 2.3 1.2 2.9 1.1 1.3 0.6 2.0 1.5 1.5 0.8 1.6 1.3 5.1 1.2 1.9 2.7 0.4 1.3 1.6 1.3 1.2 3.7 7.7 5.7 4.2 0.5 1.1 4.9 3.9 1.7 8.1 7.9 3.3 3.1 5.5 2.1 1.3 7.2 3.6 5.0 1.7 9.3 9.2 8.2 7.0 6.2 4.3 0.2 4.8 5.9 0.5 0.6 4.4 1.4 1.8 4.1 9.3 8.9 5.6 4.4 4.0 7.1 2.9 2.5 7.7 4.0 6.2 6.6 2.3 1.8 2.2 3.1 3.4 3.8 1.2 2.9 6.1 3.9 3.1 1.8 2.8 5.2 3.6 7.2 2.6 3.5 7.2 2.1 4.1 4.3 0.0 0.1 0.4 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.1 0.1 1.1 1.1 1.2 1.8 1.1 1.0 1.1 1.0 1.1 0.8 1.2 1.2 2.1 0.0 1.1 15.0 4.0 0.6 2.6 1.2 1.2 30.0 1.5 1.3 1.1 0.0 2.1 5.5 12.5 4.2 5.8 0.6 0.0 0.3 8.1 2.0 2.2 2.8 4.2 5.5 11.4 0.8 1.4 2.3 1.5 1.1 3.8 9.6 3.3 0.3 1.4 30.3 11.0 0.3 0.0 1.3 3.1 7.4 1.2 2.5 5.4 5.6 1.4 7.2 2.1 7.5 30.9 0.2 0.2 3.0 3.4 2.0 0.7 0.5 1.9 15.7 0.0 4.5 2.0 35.7 16.5 1.9 0.1 1.4 1.4 5.3 1.1 2.3 DCLRE1B "APOLLO, FLJ12810, FLJ13998, SNM1B" ENSG00000118655 "DNA cross-link repair 1B" Q9H816 1 113905213-113914086 "Disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 23.6;Sertoli cells: 26.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 57.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064934 Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Nuclear bodies" "HPA064934: AB_2685387" "unprognostic (1.21e-1)" "unprognostic (3.38e-2)" "unprognostic (4.47e-3)" "unprognostic (4.92e-3)" "unprognostic (1.89e-1)" "unprognostic (1.02e-2)" "prognostic unfavorable (4.50e-5)" "unprognostic (1.31e-2)" "unprognostic (9.67e-3)" "unprognostic (2.73e-2)" "prognostic unfavorable (6.70e-4)" "unprognostic (1.15e-1)" "prognostic unfavorable (5.03e-7)" "unprognostic (1.24e-2)" "unprognostic (2.13e-1)" "unprognostic (1.25e-1)" "unprognostic (5.08e-2)" 3.5 1.2 2.5 3.7 2.7 6.0 2.9 4.5 2.8 2.5 2.1 2.8 1.7 2.4 1.6 3.0 2.7 2.2 1.3 2.4 2.7 1.6 1.7 3.2 4.1 2.5 2.7 3.0 0.9 1.1 0.7 3.5 2.5 1.7 3.0 1.2 1.2 1.9 0.8 2.6 1.9 3.3 2.5 4.0 1.6 2.4 2.8 4.8 2.0 1.0 3.9 2.2 1.6 3.3 14.1 5.5 9.9 10.5 7.9 5.4 5.7 11.1 7.4 14.2 15.3 6.0 3.9 14.3 6.8 7.8 6.4 6.4 13.7 11.2 19.6 12.0 10.1 12.4 7.8 5.9 1.5 14.1 12.1 6.2 4.4 18.5 10.6 3.9 7.9 16.5 17.5 11.8 16.7 57.8 21.7 11.5 7.7 5.5 12.6 17.2 30.4 6.5 5.6 6.1 8.7 8.0 12.0 9.2 7.7 7.8 6.1 14.9 4.8 18.6 19.6 31.3 15.8 5.2 5.6 16.0 15.7 13.8 32.9 1.9 4.5 1.3 2.3 3.7 2.5 0.9 2.6 2.2 2.6 1.4 1.7 2.2 0.2 5.8 2.1 1.0 1.8 2.5 2.5 2.7 4.5 2.8 2.4 2.7 2.5 2.7 2.5 2.5 2.8 3.3 3.0 3.2 2.0 0.3 2.8 3.6 1.2 1.7 8.0 3.0 2.6 2.0 1.2 1.5 0.8 0.0 2.1 4.6 4.0 1.0 1.9 4.4 1.3 4.1 2.3 3.4 3.0 23.6 0.8 2.7 9.8 3.4 0.5 2.4 1.3 5.6 2.2 1.6 9.7 1.7 0.9 3.1 2.0 8.5 12.8 0.6 1.8 10.5 0.0 1.0 13.5 0.9 2.1 0.0 1.1 3.7 0.5 2.2 5.0 1.5 0.3 1.7 3.1 1.4 26.3 2.1 5.5 7.9 11.4 6.2 2.7 1.4 4.4 3.0 4.2 1.0 DCTN6 WS-3 ENSG00000104671 "Dynactin subunit 6" O00399 8 30156319-30183639 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024049, HPA024558" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Cytosol" "Plasma membrane" "HPA024049: AB_1847524, HPA024558: AB_1847525" "unprognostic (1.28e-1)" "unprognostic (8.32e-3)" "unprognostic (1.65e-2)" "unprognostic (1.88e-1)" "unprognostic (1.69e-1)" "unprognostic (7.50e-2)" "prognostic unfavorable (5.51e-4)" "unprognostic (1.26e-1)" "unprognostic (7.84e-2)" "unprognostic (1.08e-2)" "unprognostic (2.38e-2)" "unprognostic (9.26e-2)" "prognostic favorable (5.42e-4)" "unprognostic (1.06e-1)" "unprognostic (3.10e-1)" "unprognostic (7.54e-2)" "unprognostic (1.43e-1)" 50.6 54.1 48.0 26.6 51.1 43.7 53.0 51.8 74.1 32.3 42.3 37.5 23.8 38.2 43.5 34.3 30.1 32.8 75.6 50.4 54.8 54.2 46.7 34.0 28.3 50.8 49.8 41.5 32.0 72.8 29.7 53.6 51.1 34.7 36.2 42.4 33.6 36.7 36.6 29.0 26.1 42.6 52.9 27.6 31.9 21.9 50.5 37.8 54.6 43.5 31.2 45.8 31.6 58.6 53.6 51.9 64.4 33.8 59.3 80.7 42.1 72.8 87.0 70.4 74.9 33.6 35.8 41.0 76.0 78.8 64.9 39.6 46.1 64.2 83.8 32.4 34.3 57.8 40.9 54.5 45.8 33.6 47.4 68.2 90.4 51.2 54.8 61.5 65.2 58.0 66.4 44.3 77.0 41.7 62.4 53.0 51.6 93.8 32.0 32.4 48.7 35.3 104.6 54.1 105.4 60.0 42.7 53.0 77.9 32.4 50.4 48.3 60.8 37.4 128.9 31.9 52.4 18.1 22.2 51.8 69.7 38.1 68.1 16.7 13.5 5.0 8.1 15.8 9.1 7.1 7.5 9.8 15.9 5.3 9.5 11.4 3.7 11.2 15.9 20.8 8.1 6.8 48.0 51.1 51.8 74.1 50.4 54.8 50.8 49.8 51.1 52.9 50.5 58.6 61.3 25.6 39.7 19.9 34.9 57.2 91.3 127.1 25.6 36.4 45.4 43.2 83.4 47.1 85.3 44.1 14.6 88.5 48.9 28.1 123.3 94.5 18.0 32.5 37.2 58.7 40.8 28.2 19.0 84.5 87.7 56.6 25.0 39.6 46.9 44.0 45.7 42.7 71.4 26.9 17.3 31.6 91.6 43.9 54.8 12.5 80.8 43.2 69.4 15.0 58.4 63.3 17.5 17.6 21.3 91.1 43.1 75.2 32.3 48.8 36.3 147.1 71.6 40.3 52.6 63.1 66.0 44.2 47.3 38.0 63.5 203.6 59.8 49.5 33.0 95.0 DCTPP1 "CDA03, MGC5627, RS21C6, XTP3TPA" ENSG00000179958 "DCTP pyrophosphatase 1" Q9H773 16 30423615-30430030 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002832 Uncertain Supported Nucleoplasm,Cytosol NA Yes 61000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "HPA002832: AB_1080615" "prognostic unfavorable (1.64e-5)" "unprognostic (1.61e-1)" "unprognostic (1.99e-3)" "unprognostic (1.17e-2)" "unprognostic (1.36e-1)" "unprognostic (4.09e-2)" "prognostic unfavorable (6.28e-4)" "unprognostic (2.23e-1)" "unprognostic (1.07e-1)" "unprognostic (4.35e-2)" "unprognostic (2.43e-2)" "unprognostic (3.65e-2)" "prognostic favorable (9.71e-9)" "unprognostic (1.10e-3)" "unprognostic (8.78e-3)" "unprognostic (1.10e-2)" "unprognostic (2.53e-1)" 21.0 21.4 17.6 27.4 18.4 22.2 30.5 18.7 22.5 18.6 18.9 56.4 32.0 18.6 20.0 28.3 28.1 19.5 31.1 18.4 19.5 39.7 21.8 16.2 35.5 18.1 17.6 14.0 24.9 32.1 10.3 16.0 19.0 21.8 58.4 12.2 25.5 19.3 44.7 25.1 27.7 20.5 18.4 27.8 24.3 9.1 18.1 24.5 20.1 36.9 35.7 27.0 19.1 19.4 124.7 149.8 66.8 85.8 18.4 24.1 61.9 58.4 35.1 87.4 87.9 114.7 103.4 168.1 119.1 36.8 54.9 95.9 141.4 115.1 103.5 89.2 221.0 98.3 61.5 150.3 24.1 177.0 144.2 28.6 64.8 96.4 55.6 25.4 88.7 88.2 125.8 57.4 61.5 217.8 210.0 189.9 88.8 124.2 119.2 293.1 74.8 218.1 98.9 80.2 141.4 80.4 39.0 137.7 55.3 41.5 118.4 73.9 45.9 66.0 59.1 85.8 107.2 36.9 118.4 217.5 43.8 145.7 79.6 70.6 36.7 38.1 54.0 70.0 75.8 146.7 68.4 61.4 86.7 128.7 60.9 59.0 4.6 76.1 79.2 94.6 76.4 81.0 17.6 18.4 18.7 22.5 18.4 19.5 18.1 17.6 19.0 18.4 18.1 19.4 34.0 19.2 15.2 0.7 38.2 90.2 53.3 92.5 33.6 23.3 45.8 48.9 34.8 51.5 37.9 44.1 8.4 103.2 22.7 130.3 127.2 135.6 13.4 32.6 29.9 47.4 38.5 29.6 2.6 124.8 101.0 28.3 27.5 66.5 31.1 40.2 31.1 23.2 76.9 15.2 2.7 142.3 73.2 21.0 49.1 45.1 19.6 26.9 48.0 1.0 73.2 25.0 23.7 2.5 4.4 89.0 115.8 19.9 24.1 86.9 68.8 76.7 27.8 21.4 19.7 23.7 40.0 3.3 44.8 39.4 80.3 27.8 28.3 53.8 168.5 45.7 DDX11 "CHL1, CHLR1, KRG2, WABS" ENSG00000013573 "DEAD/H-box helicase 11" Q96FC9 12 31073860-31104799 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Host-virus interaction, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Helicase, Hydrolase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 25.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA065197 Supported Supported Nucleoplasm,Nucleoli No Yes "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 5: NTERA-2 - Transcription" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "HPA065197: AB_2685430" "unprognostic (6.10e-2)" "unprognostic (1.48e-2)" "unprognostic (1.02e-1)" "unprognostic (5.09e-2)" "unprognostic (1.45e-1)" "unprognostic (2.79e-3)" "prognostic unfavorable (2.40e-4)" "unprognostic (4.87e-2)" "unprognostic (3.89e-3)" "unprognostic (3.53e-1)" "unprognostic (5.66e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (5.23e-8)" "unprognostic (1.89e-2)" "unprognostic (3.64e-2)" "unprognostic (1.02e-1)" "unprognostic (8.03e-3)" 5.9 6.4 6.0 10.2 6.8 29.2 7.2 6.9 7.3 10.7 7.1 9.6 8.0 7.5 4.3 9.5 8.0 5.9 5.3 6.0 6.1 9.2 9.3 6.1 13.2 6.9 6.4 11.0 17.5 5.8 9.4 5.4 6.9 10.0 10.1 6.6 8.6 5.3 10.6 16.7 13.4 3.6 6.1 13.8 9.6 8.8 6.7 24.0 8.0 6.6 11.1 6.9 9.8 6.9 36.5 35.0 42.2 34.5 5.8 11.0 58.7 21.8 10.4 25.2 28.5 44.1 58.6 49.2 23.9 10.8 23.6 35.0 31.7 28.9 21.3 43.4 66.6 47.4 71.0 25.4 2.1 37.4 35.0 11.9 13.0 32.6 24.8 16.9 12.6 55.2 26.6 103.3 17.6 30.9 64.5 60.7 84.0 39.9 19.5 55.0 53.3 66.2 13.3 38.5 30.2 21.7 23.4 33.2 10.4 65.0 27.3 25.5 8.2 22.0 42.1 42.2 40.0 39.4 29.6 95.3 24.6 32.5 20.3 0.0 1.3 0.8 2.0 1.2 1.5 2.5 1.9 1.5 1.5 2.6 2.0 2.6 0.5 2.2 4.4 2.4 2.0 1.3 6.0 6.8 6.9 7.3 6.0 6.1 6.9 6.4 6.9 6.1 6.7 6.9 10.1 3.2 9.5 1.6 9.0 6.0 4.0 6.0 2.2 9.4 8.3 7.1 2.5 4.3 6.0 0.0 14.6 7.6 8.8 7.8 0.0 2.0 1.7 5.5 8.9 5.4 0.0 15.3 2.5 3.3 7.5 5.7 9.7 7.4 5.7 15.6 6.1 7.7 5.2 8.4 3.6 6.5 10.2 4.1 5.4 1.3 7.2 4.4 7.2 3.7 3.5 2.7 4.1 1.5 1.7 3.2 2.7 4.5 17.2 6.0 2.3 1.4 6.7 25.8 0.0 4.9 4.8 5.3 18.0 5.5 6.5 2.6 8.4 4.1 9.5 5.1 DEPDC1 "DEP.8, DEPDC1A, FLJ20354, SDP35" ENSG00000024526 "DEP domain containing 1" Q5TB30 1 68474152-68497221 "Predicted intracellular proteins" "Transcription, Transcription regulation" "GTPase activation, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.0;lymphoid tissue: 8.1;testis: 8.1" "Cell type enhanced" "Detected in many" "Early spermatids: 44.9;Erythroid cells: 31.8;Extravillous trophoblasts: 35.2;Late spermatids: 73.0;Spermatocytes: 86.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" CAB017845 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli fibrillar center" "CAB017845: " "unprognostic (2.73e-1)" "unprognostic (7.40e-2)" "prognostic favorable (8.70e-5)" "unprognostic (1.23e-3)" "unprognostic (3.06e-1)" "unprognostic (7.73e-3)" "unprognostic (4.37e-6)" "unprognostic (3.39e-3)" "unprognostic (1.57e-3)" "unprognostic (8.59e-2)" "unprognostic (9.04e-6)" "unprognostic (2.18e-1)" "unprognostic (0.00e+0)" "unprognostic (2.39e-2)" "unprognostic (2.27e-1)" "unprognostic (2.83e-2)" "unprognostic (1.11e-1)" 0.3 0.1 0.0 2.6 0.0 5.0 0.6 0.0 0.1 0.4 0.0 2.9 2.5 0.5 0.1 2.4 0.1 0.5 0.1 0.1 0.0 0.0 0.4 0.2 4.8 0.0 0.1 0.0 0.0 0.2 0.0 3.2 0.1 2.1 3.5 0.0 0.3 0.1 0.0 1.6 2.4 1.5 0.0 0.6 1.2 8.1 0.2 8.1 0.3 0.2 4.8 0.9 0.7 0.2 47.2 21.5 40.0 18.5 2.5 5.6 31.3 58.9 26.9 49.1 42.1 17.9 19.3 0.0 42.8 24.4 78.6 30.8 58.6 30.7 82.4 41.2 38.2 38.3 35.9 10.5 0.6 33.4 0.0 2.1 1.6 56.3 31.2 10.0 36.0 16.5 26.6 36.1 88.3 10.7 0.1 12.5 34.6 19.5 28.9 0.0 118.7 15.3 19.8 12.7 44.8 20.7 59.0 24.9 30.3 25.6 22.5 16.6 21.3 31.5 35.5 56.0 69.2 22.5 52.2 0.5 29.7 11.4 65.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.4 0.0 0.0 0.3 2.0 3.3 0.8 3.3 1.2 0.4 1.3 1.8 0.8 0.0 0.5 1.8 0.0 20.6 0.4 2.1 0.0 0.2 44.9 4.0 1.6 1.6 0.0 31.8 0.5 0.0 35.2 4.4 8.2 2.0 0.0 17.5 2.2 1.2 8.6 0.0 2.2 5.3 4.1 3.5 1.0 73.0 0.3 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.4 6.9 2.2 0.5 0.1 0.9 0.2 0.0 0.6 4.0 86.8 19.6 12.2 1.3 2.9 1.6 0.5 8.8 1.7 DEPDC1B "BRCC3, XTP1" ENSG00000035499 "DEP domain containing 1B" Q8WUY9 5 60596912-60700190 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 11.1;gallbladder: 21.0;lymphoid tissue: 20.7;testis: 12.6" "Cell type enhanced" "Detected in many" "Cholangiocytes: 18.6;Erythroid cells: 23.8;Extravillous trophoblasts: 21.6;Spermatocytes: 37.2;Syncytiotrophoblasts: 46.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "T-reg: 3.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA038255, HPA072558" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA038255: AB_10669521, HPA072558: AB_2686534" "unprognostic (1.38e-1)" "unprognostic (1.99e-2)" "prognostic favorable (2.42e-4)" "prognostic unfavorable (8.55e-4)" "unprognostic (2.23e-1)" "unprognostic (7.93e-2)" "prognostic unfavorable (3.08e-4)" "prognostic unfavorable (6.93e-5)" "unprognostic (2.13e-2)" "unprognostic (8.14e-2)" "unprognostic (1.47e-3)" "unprognostic (2.44e-2)" "unprognostic (1.11e-16)" "unprognostic (1.00e-1)" "unprognostic (1.40e-1)" "unprognostic (1.53e-1)" "unprognostic (8.62e-2)" 0.3 0.2 0.4 3.9 0.7 11.1 0.9 0.5 0.5 0.6 0.1 4.1 6.0 0.6 0.0 2.5 0.2 21.0 0.1 0.3 0.6 2.9 0.4 0.4 9.1 1.2 0.5 0.2 0.1 0.0 0.0 7.5 1.4 0.2 5.5 0.1 0.5 0.1 0.0 2.1 6.4 0.9 0.6 1.6 1.4 12.6 0.6 20.7 1.2 0.0 9.7 1.0 1.1 1.5 61.0 20.3 60.5 37.2 1.3 1.9 66.2 16.1 10.9 27.7 35.8 34.0 37.5 34.6 38.5 5.0 36.0 19.8 49.2 36.1 36.9 49.5 35.5 43.3 22.7 42.6 1.0 36.7 40.3 1.2 3.7 9.0 12.9 5.4 26.1 36.3 31.4 45.8 24.7 38.0 59.8 31.9 44.7 13.0 32.6 65.4 49.2 29.4 22.8 29.9 33.6 15.4 37.7 13.4 17.7 27.0 24.9 28.8 12.1 11.7 34.2 9.5 41.6 23.0 43.3 68.0 14.7 53.2 33.3 1.5 0.1 0.9 0.2 0.0 0.2 0.4 1.0 0.7 0.3 0.0 0.1 0.1 0.0 0.6 0.0 0.0 3.2 0.4 0.4 0.7 0.5 0.5 0.3 0.6 1.2 0.5 1.4 0.6 0.6 1.5 0.2 0.0 1.8 0.0 1.9 4.7 1.0 1.5 0.0 0.1 0.5 0.8 0.1 18.6 0.3 0.0 0.0 7.4 1.1 3.1 0.0 0.3 1.9 3.3 1.4 0.9 0.0 23.8 5.5 0.2 21.6 1.1 2.6 11.7 3.8 5.2 0.0 0.3 6.4 0.0 1.7 2.3 0.0 1.6 2.9 2.4 0.3 1.9 0.0 4.7 0.1 0.2 0.0 2.0 7.0 0.9 5.8 0.0 15.9 0.7 3.7 1.0 0.1 0.1 6.6 0.3 1.4 37.2 12.7 5.8 2.0 46.9 4.5 0.6 7.9 0.9 DHFR ENSG00000228716 "Dihydrofolate reductase" P00374 5 80626226-80654983 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Methotrexate resistance, One-carbon metabolism" "Oxidoreductase, RNA-binding" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 145.8;Spermatocytes: 132.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037129, HPA051465" Uncertain Approved Mitochondria NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "CAB037129: AB_439683, HPA051465: AB_2681494" "unprognostic (1.44e-2)" "unprognostic (1.03e-2)" "unprognostic (2.24e-3)" "unprognostic (2.91e-3)" "unprognostic (3.27e-1)" "unprognostic (1.32e-1)" "unprognostic (2.83e-2)" "unprognostic (2.35e-2)" "unprognostic (2.02e-2)" "unprognostic (4.19e-3)" "unprognostic (1.83e-2)" "unprognostic (2.55e-1)" "unprognostic (1.15e-2)" "unprognostic (1.82e-2)" "unprognostic (2.49e-1)" "unprognostic (1.57e-1)" "unprognostic (1.09e-1)" 25.2 5.3 15.3 20.7 16.5 54.3 12.0 15.8 21.9 8.0 13.3 21.4 24.5 8.6 7.0 14.1 7.4 8.5 7.2 13.8 15.5 21.3 60.1 7.5 41.5 16.6 16.6 6.6 3.2 9.1 6.3 14.4 16.6 8.9 25.3 10.3 6.8 9.5 19.6 9.8 25.1 12.0 16.5 10.3 12.2 18.5 15.8 60.7 8.2 25.8 39.5 10.3 5.7 17.7 98.1 66.6 164.8 122.7 30.7 32.0 60.6 76.5 58.1 130.2 149.0 63.8 114.6 196.9 32.5 44.6 106.0 67.0 214.4 98.6 208.5 88.2 132.1 94.8 104.5 59.5 6.6 111.7 40.3 22.3 9.9 116.9 13.0 22.2 63.9 142.0 108.3 146.7 133.5 98.2 276.5 44.9 83.6 48.3 38.5 176.7 323.3 194.1 75.1 61.5 134.3 93.7 107.9 49.9 54.6 83.5 98.5 108.6 38.5 41.0 62.0 116.0 148.3 68.2 146.6 210.3 91.5 222.1 107.7 0.2 0.3 0.2 0.5 0.6 0.2 0.5 0.6 0.8 0.5 0.5 0.5 0.6 0.8 0.5 0.5 0.8 0.9 0.6 15.3 16.5 15.8 21.9 13.8 15.5 16.6 16.6 16.6 16.5 15.8 17.7 4.1 6.4 11.7 4.9 21.4 6.9 6.5 6.0 4.0 3.5 8.9 8.9 13.0 4.3 6.1 14.7 2.1 35.2 7.4 19.3 9.8 7.4 7.4 10.8 7.7 7.7 4.9 145.8 7.3 3.7 47.3 12.0 11.7 8.0 2.5 22.0 10.0 48.3 44.7 3.3 7.2 19.1 4.1 18.9 4.4 6.4 14.0 12.8 0.0 4.7 7.1 14.5 13.4 3.5 6.0 4.7 10.3 16.1 60.9 2.9 26.6 40.0 6.9 3.2 13.1 9.0 12.5 132.2 49.8 21.2 5.5 13.3 11.8 12.3 38.1 12.1 DIABLO "DFNA64, DIABLO-S, FLJ10537, FLJ25049, SMAC" ENSG00000184047 "Diablo IAP-binding mitochondrial protein" Q9NR28 12 122207663-122227456 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 31.3;Plasma cells: 29.2;Squamous epithelial cells: 30.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001825, CAB003857, CAB016688" Supported Enhanced Mitochondria NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Mitochondria "CAB003857: AB_365498, CAB016688: AB_1615783, HPA001825: AB_1857247" "unprognostic (3.67e-2)" "unprognostic (1.90e-1)" "unprognostic (1.11e-1)" "unprognostic (3.10e-3)" "unprognostic (1.64e-1)" "unprognostic (2.38e-3)" "unprognostic (1.40e-3)" "unprognostic (5.06e-2)" "unprognostic (1.48e-1)" "unprognostic (1.03e-1)" "unprognostic (1.33e-2)" "unprognostic (4.05e-2)" "prognostic unfavorable (5.35e-4)" "unprognostic (6.68e-2)" "unprognostic (2.36e-1)" "unprognostic (2.00e-1)" "unprognostic (1.40e-1)" 23.8 34.3 29.8 17.3 30.8 32.5 25.3 33.7 36.8 21.4 30.4 28.7 21.7 27.0 36.1 30.8 23.3 18.0 30.3 28.7 32.0 34.5 39.6 21.2 21.0 32.0 31.4 27.8 27.7 32.2 41.4 25.8 32.1 21.9 24.5 27.5 28.9 19.5 37.4 25.4 26.9 20.5 33.6 24.3 26.6 53.2 31.0 26.9 25.8 34.5 24.9 32.0 24.5 33.4 49.0 94.7 65.4 44.7 45.9 44.6 50.2 49.5 48.3 56.9 50.8 82.4 24.9 59.2 45.4 45.2 42.4 47.4 72.2 59.3 67.0 51.1 56.4 65.2 36.6 76.7 65.3 71.0 25.9 62.2 41.3 67.3 100.1 64.4 66.8 57.9 75.9 24.5 56.1 72.4 58.6 103.8 52.9 69.5 88.0 52.3 65.2 65.4 64.4 74.7 61.7 62.6 66.1 26.2 54.8 73.3 87.9 49.2 46.0 43.7 53.6 50.0 45.4 52.8 95.5 84.3 55.8 53.6 58.8 43.3 39.8 39.8 39.9 41.4 37.8 46.3 36.4 37.2 48.3 36.4 35.6 36.1 17.9 45.5 40.1 37.5 46.3 42.0 29.8 30.8 33.7 36.8 28.7 32.0 32.0 31.4 32.1 33.6 31.0 33.4 0.2 0.0 0.6 7.2 19.7 5.0 5.9 7.6 31.3 7.3 0.0 0.0 1.3 10.0 3.3 0.0 4.2 11.3 3.0 8.2 0.0 0.2 6.3 0.0 0.0 3.8 7.3 20.4 14.5 0.0 10.8 7.7 25.5 0.0 4.5 0.0 5.3 2.9 6.5 3.3 14.1 8.8 8.2 3.3 3.6 4.6 5.6 7.1 3.6 3.7 2.7 7.6 9.2 9.0 15.1 0.2 11.9 3.4 29.2 3.9 16.8 0.1 1.7 11.1 6.6 2.6 4.9 19.2 16.3 30.4 4.8 13.4 13.2 0.0 9.9 3.9 DIAPH3 "AN, AUNA1, DRF3, FLJ34705, NSDAN" ENSG00000139734 "Diaphanous related formin 3" Q9NSV4 13 59665583-60163928 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Deafness, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 7.1;testis: 18.9" "Cell type enriched" "Detected in many" 5 "Early spermatids: 414.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA032151 Supported "Plasma membrane,Microtubules" NA Yes "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Microtubules" "HPA032151: AB_2674181" "unprognostic (3.78e-2)" "unprognostic (1.28e-2)" "prognostic favorable (9.04e-4)" "prognostic unfavorable (4.18e-4)" "unprognostic (2.78e-1)" "unprognostic (4.69e-2)" "unprognostic (1.27e-4)" "prognostic unfavorable (3.72e-4)" "unprognostic (1.74e-2)" "unprognostic (2.19e-1)" "unprognostic (5.22e-5)" "unprognostic (3.59e-3)" "unprognostic (5.31e-5)" "unprognostic (4.30e-2)" "unprognostic (2.37e-1)" "unprognostic (4.07e-1)" "unprognostic (2.74e-3)" 0.4 0.1 0.1 1.7 0.2 7.1 0.8 0.3 0.3 0.3 0.2 1.9 1.9 0.6 0.0 2.1 0.1 0.4 0.1 0.1 0.2 0.8 0.2 1.2 2.4 0.2 0.3 0.1 0.2 0.1 0.0 3.5 0.2 0.1 2.1 0.0 0.5 0.0 0.0 1.3 1.6 2.6 0.1 0.5 1.6 18.9 0.3 5.4 0.1 0.0 2.4 0.6 0.7 0.2 47.7 15.6 15.8 9.1 2.7 7.1 26.9 65.0 28.7 64.2 55.6 41.7 31.4 15.9 5.2 33.4 16.7 31.7 26.0 25.5 96.9 18.0 17.9 22.7 37.6 9.5 4.1 31.2 17.4 2.8 0.6 39.2 26.3 16.3 29.2 14.0 17.8 21.9 61.8 6.9 28.0 10.2 14.7 22.5 8.9 18.8 38.9 12.9 19.9 9.6 8.3 14.3 33.2 22.8 9.5 33.8 16.7 16.8 29.3 40.5 25.9 13.7 54.5 14.7 17.1 24.4 10.9 15.2 31.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.3 0.3 0.1 0.2 0.2 0.3 0.2 0.1 0.3 0.2 0.6 54.5 3.4 39.8 1.9 3.7 0.8 2.1 2.8 0.0 3.9 1.5 1.0 2.8 1.8 0.0 0.0 21.1 1.1 3.8 5.9 1.3 414.4 2.5 3.5 2.1 0.0 26.7 5.6 4.0 30.7 5.8 9.7 9.3 0.0 78.8 1.8 0.4 6.1 0.0 3.3 2.6 2.0 1.0 1.2 56.0 0.6 1.5 0.0 5.6 0.1 3.5 2.1 19.1 1.8 1.5 0.2 0.0 18.9 0.4 1.1 5.4 0.2 0.0 0.0 0.0 7.9 39.2 17.8 11.6 1.1 7.3 2.2 2.8 5.6 1.5 DLGAP5 "DLG1, DLG7, HURP, KIAA0008" ENSG00000126787 "DLG associated protein 5" Q15398 14 55148112-55191608 "Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 29.7;lymphoid tissue: 42.0;testis: 17.4" "Cell type enhanced" "Detected in many" "Erythroid cells: 92.6;Extravillous trophoblasts: 23.1;Plasma cells: 22.1;Spermatocytes: 68.1;Spermatogonia: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 5.4" "Lineage enriched" "Detected in many" 5 "T-cells: 5.4" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA005546 Enhanced Supported "Centriolar satellite,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Centriolar satellite, Cytosol" "HPA005546: AB_1078677" "unprognostic (2.24e-1)" "unprognostic (1.77e-1)" "unprognostic (1.19e-3)" "prognostic unfavorable (4.59e-4)" "unprognostic (1.42e-1)" "unprognostic (1.66e-2)" "prognostic unfavorable (1.52e-6)" "prognostic unfavorable (7.85e-4)" "unprognostic (6.15e-3)" "unprognostic (3.55e-1)" "prognostic unfavorable (9.94e-6)" "unprognostic (4.69e-2)" "unprognostic (0.00e+0)" "unprognostic (1.06e-2)" "unprognostic (3.64e-1)" "unprognostic (1.29e-1)" "unprognostic (1.93e-2)" 0.8 0.3 1.4 8.1 0.9 29.7 1.4 0.4 1.8 0.8 0.6 5.5 5.0 1.3 0.1 5.2 0.4 0.8 0.2 1.0 1.7 0.2 0.7 0.7 17.9 0.7 1.0 0.2 0.1 0.2 0.0 4.1 0.8 0.2 6.7 0.1 0.8 0.1 0.1 3.1 4.6 2.7 0.3 2.6 3.0 17.4 1.1 42.0 0.4 0.0 18.7 2.0 1.5 3.8 144.8 56.8 140.6 63.7 3.3 13.4 43.8 80.3 52.7 115.3 109.3 45.9 75.8 82.1 44.2 46.9 47.4 85.6 91.5 64.0 150.5 101.9 45.7 84.4 49.9 39.3 0.4 82.7 49.3 2.8 2.2 54.8 27.0 18.9 129.0 82.5 70.5 79.8 109.3 69.2 105.0 42.7 72.6 63.3 57.3 80.8 137.9 39.0 37.9 45.2 71.7 40.7 84.8 31.7 30.8 60.6 71.6 31.6 49.6 52.4 133.3 50.6 94.6 19.4 44.9 108.9 35.9 59.6 83.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.9 1.4 0.3 0.0 0.2 0.1 0.2 1.0 0.0 0.0 5.4 0.7 1.4 0.9 0.4 1.8 1.0 1.7 0.7 1.0 0.8 0.3 1.1 3.8 0.1 0.0 0.5 0.0 4.4 1.1 0.7 3.3 0.0 0.0 1.2 0.9 0.4 0.0 1.3 0.0 0.0 11.6 1.4 3.2 0.0 0.4 19.7 7.2 2.6 2.4 0.0 92.6 0.3 0.0 23.1 4.2 7.7 4.5 0.0 15.8 3.9 0.5 10.5 0.0 0.3 3.6 8.2 4.1 1.6 6.0 0.9 3.7 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.2 0.2 1.2 22.1 0.6 0.3 0.1 1.3 0.0 6.6 0.0 3.8 68.1 31.7 11.6 0.4 1.9 4.0 0.9 6.9 1.4 DNA2 "DNA2L, KIAA0083" ENSG00000138346 "DNA replication helicase/nuclease 2" P51530 10 68414064-68472121 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, Endonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease" "Disease variant, Dwarfism, Mental retardation, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 33.2;Excitatory neurons: 14.1;Inhibitory neurons: 15.5;Oligodendrocytes: 18.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "NK-cell: 1.8" "Lineage enriched" "Detected in single" 5 "NK-cells: 1.8" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA037487, HPA057526" Approved Supported Mitochondria No Yes "Cluster 15: NK-cells - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "HPA037487: AB_10672493, HPA057526: AB_2683456" "unprognostic (1.79e-1)" "unprognostic (1.35e-1)" "unprognostic (4.37e-3)" "unprognostic (4.60e-3)" "unprognostic (1.53e-1)" "unprognostic (1.86e-2)" "unprognostic (4.50e-5)" "unprognostic (3.36e-2)" "unprognostic (4.70e-2)" "unprognostic (3.72e-2)" "unprognostic (1.30e-2)" "unprognostic (3.29e-4)" "unprognostic (1.09e-10)" "unprognostic (3.43e-2)" "unprognostic (1.98e-1)" "unprognostic (9.36e-2)" "unprognostic (1.23e-2)" 1.3 0.9 1.9 2.8 2.1 4.6 1.8 2.5 3.6 1.4 1.0 2.3 2.1 1.1 0.9 1.9 0.9 0.9 1.8 1.8 1.9 2.6 4.2 1.8 5.2 2.3 1.9 1.2 1.6 0.4 1.5 1.6 2.4 1.9 2.8 5.3 1.6 0.4 1.6 1.8 3.2 1.1 1.6 2.1 1.9 2.9 2.1 8.1 1.0 0.9 4.2 1.4 1.4 3.2 25.6 13.0 29.0 20.7 3.2 2.2 20.4 12.4 10.3 17.4 21.2 31.1 16.1 26.1 4.6 3.8 6.7 15.2 16.8 6.5 20.7 16.2 12.6 15.8 8.5 12.3 0.9 27.7 16.4 1.8 2.6 12.3 3.6 4.5 7.9 17.0 23.6 22.8 10.1 9.0 42.8 19.8 20.5 10.9 24.0 33.1 20.0 8.4 7.5 11.7 13.1 15.7 16.9 21.4 4.2 20.1 16.5 11.6 3.4 6.6 20.5 8.5 23.8 11.5 13.9 38.3 5.7 26.1 8.9 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.1 0.1 0.0 1.8 0.0 0.0 0.1 0.0 1.9 2.1 2.5 3.6 1.8 1.9 2.3 1.9 2.4 1.6 2.1 3.2 1.0 6.4 1.1 4.9 1.3 2.3 0.9 1.7 2.8 2.5 2.3 1.4 10.5 2.8 1.1 1.8 6.2 3.9 2.2 1.7 0.0 0.8 2.2 2.0 1.4 2.0 1.2 33.2 14.1 0.9 4.8 2.0 2.6 2.8 0.0 6.0 0.7 4.6 2.2 0.0 15.5 1.8 0.0 1.3 0.7 3.7 0.6 1.5 0.0 4.7 0.5 0.5 2.1 5.5 18.4 0.7 0.1 0.7 7.4 2.5 2.4 0.6 0.8 4.3 0.0 2.4 1.1 9.1 12.2 4.7 1.7 1.2 1.6 0.7 3.7 1.0 DNAJA1 "dj-2, hdj-2, HSJ2, HSPF4, NEDD7" ENSG00000086061 "DnaJ heat shock protein family (Hsp40) member A1" P31689 9 33025273-33039907 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 438.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001306, CAB033665" Approved Supported Microtubules,Cytosol NA Yes 160000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 65: Brain - Ion transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Cytosol Microtubules "CAB033665: AB_2094242, HPA001306: AB_1079043" "unprognostic (3.11e-2)" "unprognostic (5.05e-2)" "unprognostic (5.14e-2)" "unprognostic (1.16e-1)" "unprognostic (1.07e-1)" "unprognostic (9.80e-2)" "unprognostic (3.17e-2)" "unprognostic (2.88e-2)" "unprognostic (5.58e-2)" "prognostic favorable (5.39e-4)" "unprognostic (1.69e-2)" "unprognostic (1.05e-1)" "prognostic favorable (3.40e-4)" "unprognostic (3.27e-1)" "unprognostic (2.65e-1)" "unprognostic (1.25e-1)" "unprognostic (4.70e-2)" 102.6 134.7 143.9 83.9 154.7 148.8 65.8 147.4 438.9 83.7 142.7 61.9 44.5 81.0 80.4 51.7 102.7 83.6 72.9 154.1 159.8 114.6 216.9 94.4 80.6 147.7 152.8 83.5 59.7 105.2 80.7 108.3 160.9 85.8 63.5 78.2 61.0 64.7 47.3 43.8 50.1 87.2 155.3 72.0 67.7 135.0 164.6 95.7 66.0 61.5 89.1 130.7 57.3 174.0 255.6 447.5 353.7 123.6 240.2 155.1 202.4 256.5 205.9 451.2 348.2 299.2 115.0 259.5 191.6 175.4 254.9 113.1 515.7 154.7 386.1 368.2 150.2 208.3 537.3 382.7 115.1 242.5 234.2 96.1 156.1 170.4 53.9 218.4 273.6 110.9 330.5 109.7 262.0 208.6 407.7 530.3 345.3 254.2 308.2 294.7 126.6 132.9 254.1 148.8 223.8 243.5 345.4 220.6 120.0 262.5 103.5 231.5 236.1 160.0 273.1 184.6 346.2 69.9 233.3 271.7 209.9 208.3 140.9 154.1 140.8 160.9 93.3 202.0 111.1 127.5 116.8 105.7 127.8 119.7 119.6 113.4 176.2 117.8 268.3 213.4 110.4 209.9 143.9 154.7 147.4 438.9 154.1 159.8 147.7 152.8 160.9 155.3 164.6 174.0 1110.8 214.7 154.9 7.8 368.7 264.6 942.8 245.3 327.8 209.3 307.8 513.5 187.7 95.8 257.7 82.8 208.5 274.0 619.1 287.9 172.1 247.7 536.4 549.2 348.2 427.8 391.1 198.9 16.2 181.1 341.6 392.8 188.6 526.1 424.7 127.6 133.2 129.6 231.1 121.1 16.7 327.3 213.6 156.0 497.4 222.2 99.1 402.3 284.6 22.5 243.7 150.5 91.6 8.0 22.5 189.8 334.7 94.8 195.8 393.8 134.7 178.1 417.8 161.7 105.2 391.1 476.0 492.7 209.4 238.5 265.4 464.9 678.9 179.2 273.3 636.8 DNAJB1 "Hsp40, HSPF1, RSPH16B, Sis1" ENSG00000132002 "DnaJ heat shock protein family (Hsp40) member B1" P25685 19 14514769-14560391 "Cancer-related genes, Predicted intracellular proteins" "Stress response" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1705.1" "Cell type enhanced" "Detected in all" "Langerhans cells: 1392.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebral cortex: 1705.1" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017450, HPA063247" Enhanced Supported Nucleoplasm NA Yes 23000 "Cluster 20: T-cells - T-cell receptor" "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "CAB017450: AB_10631418, HPA063247: AB_2684971" "unprognostic (3.75e-2)" "unprognostic (2.23e-1)" "unprognostic (1.46e-1)" "unprognostic (2.12e-1)" "unprognostic (1.60e-1)" "unprognostic (1.32e-1)" "unprognostic (1.52e-1)" "unprognostic (1.74e-2)" "unprognostic (3.83e-1)" "unprognostic (1.85e-1)" "unprognostic (7.91e-3)" "unprognostic (2.17e-1)" "prognostic favorable (5.96e-4)" "unprognostic (2.20e-2)" "unprognostic (4.44e-2)" "unprognostic (2.00e-2)" "unprognostic (6.77e-2)" 206.0 216.1 228.5 40.9 241.7 133.8 62.0 320.9 1705.1 188.1 259.4 86.7 35.2 54.0 40.8 439.9 75.3 183.7 182.8 243.8 240.2 245.0 230.3 286.0 42.0 250.4 251.8 231.9 89.8 66.4 148.4 123.4 285.4 73.9 48.4 81.2 109.7 127.1 51.2 128.5 62.7 54.5 240.6 104.5 149.1 149.4 241.8 107.3 97.2 208.0 76.5 133.6 257.7 323.4 192.5 212.5 80.8 81.7 146.8 114.1 45.6 125.9 99.9 210.4 158.8 126.3 106.7 54.8 135.4 121.0 135.5 144.9 169.1 96.7 150.3 55.0 76.1 86.7 115.0 275.6 94.6 57.9 78.5 61.0 237.5 85.3 73.4 114.7 71.6 35.7 131.2 471.6 123.6 130.5 102.2 60.1 80.4 285.9 228.3 73.7 106.3 121.7 101.8 62.4 67.0 51.1 121.1 233.7 127.1 90.8 60.3 60.6 64.7 156.4 98.0 184.1 264.8 193.5 141.7 65.7 114.4 109.2 151.1 68.8 92.4 116.2 171.6 159.0 184.8 93.7 244.5 214.9 76.0 92.0 281.6 219.9 137.6 125.1 172.2 45.1 270.9 322.6 228.5 241.7 320.9 1705.1 243.8 240.2 250.4 251.8 285.4 240.6 241.8 323.4 750.2 157.0 95.4 32.3 248.7 425.8 1142.1 148.0 719.3 60.9 468.8 476.4 367.1 72.9 118.6 23.9 118.9 135.6 214.2 459.6 41.1 132.8 491.8 374.8 339.3 397.3 407.3 60.0 10.2 162.6 199.3 661.2 408.7 552.8 339.4 100.2 86.7 59.9 158.1 52.2 8.9 420.1 81.4 85.1 1392.1 475.3 63.3 559.3 503.4 23.4 31.3 160.7 25.7 3.0 16.5 123.8 380.7 36.9 697.0 461.1 117.3 59.1 138.0 164.7 26.3 398.9 673.3 290.2 53.4 1186.0 478.9 274.9 948.4 104.8 393.7 606.2 DNAJC2 "MPHOSPH11, MPP11, ZRF1, ZUO1, zuotin" ENSG00000105821 "DnaJ heat shock protein family (Hsp40) member C2" Q99543 7 103312289-103344830 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chaperone, Chromatin regulator" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 248.5;Spermatocytes: 238.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 61.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020454 Approved Supported Cytosol NA Yes "Cluster 42: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA020454: AB_1859492" "unprognostic (1.07e-1)" "unprognostic (1.66e-1)" "unprognostic (5.53e-2)" "unprognostic (2.20e-2)" "unprognostic (1.11e-1)" "unprognostic (7.71e-2)" "unprognostic (2.13e-3)" "unprognostic (2.13e-3)" "unprognostic (1.63e-2)" "unprognostic (5.35e-2)" "unprognostic (2.21e-2)" "unprognostic (1.27e-2)" "prognostic unfavorable (1.12e-5)" "unprognostic (1.11e-1)" "unprognostic (2.30e-1)" "unprognostic (3.51e-1)" "unprognostic (3.28e-1)" 15.7 13.4 10.2 12.2 10.7 42.0 13.4 12.7 19.2 13.1 10.5 11.9 14.7 12.8 9.7 13.8 12.1 9.8 13.5 10.5 10.4 16.4 15.7 11.2 16.8 10.0 10.7 15.7 13.4 9.0 12.6 11.9 10.3 12.3 11.9 8.7 12.6 7.7 32.5 13.6 11.9 7.4 9.3 12.2 12.9 31.3 11.4 12.3 12.7 12.7 13.2 18.8 12.8 11.8 52.7 38.1 21.4 38.7 16.1 22.6 41.6 35.1 25.8 38.5 28.6 52.9 37.2 74.9 53.7 24.4 55.2 35.5 57.5 25.7 58.4 40.6 43.4 55.1 38.7 47.3 28.6 97.9 41.2 19.6 21.9 44.9 39.4 16.2 25.6 27.8 128.3 46.2 32.0 83.8 95.0 102.1 75.9 56.8 57.0 59.7 43.0 70.1 22.8 24.8 40.6 38.7 47.7 66.2 39.7 39.6 28.1 49.8 30.8 37.5 59.9 83.3 68.1 48.9 67.8 146.0 27.3 97.9 47.6 61.3 9.0 9.3 10.9 10.3 12.1 11.7 10.9 11.7 9.4 13.7 12.5 12.5 3.6 16.4 15.3 11.2 12.8 5.9 10.2 10.7 12.7 19.2 10.5 10.4 10.0 10.7 10.3 9.3 11.4 11.8 31.3 25.6 47.0 10.7 46.1 64.6 78.7 37.3 35.3 27.1 26.3 36.6 32.3 22.8 50.2 22.0 41.7 43.7 45.9 31.1 35.2 45.0 248.5 43.8 50.1 39.6 35.3 29.9 24.7 46.0 75.5 41.0 42.8 44.2 53.7 50.1 18.5 30.6 39.6 21.9 17.9 39.0 26.4 24.5 41.3 37.3 39.4 37.8 19.6 13.1 42.9 19.3 44.3 24.1 20.6 50.2 32.9 31.2 36.9 79.2 36.4 31.0 43.4 29.0 39.5 63.7 64.8 238.7 131.9 33.5 62.1 55.4 43.2 58.3 51.9 91.5 DNMT1 "CXXC9, DNMT, MCMT" ENSG00000130816 "DNA methyltransferase 1" P26358 19 10133342-10231286 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Methyltransferase, Repressor, Transferase" "Deafness, Disease variant, FDA approved drug targets, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 388.1;Spermatocytes: 229.6;Syncytiotrophoblasts: 323.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002694, CAB005876" Enhanced Supported Nucleoplasm NA Yes "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "CAB005876: AB_731983, HPA002694: AB_1847810" "unprognostic (3.51e-1)" "unprognostic (1.20e-2)" "unprognostic (1.26e-2)" "unprognostic (1.40e-1)" "unprognostic (3.62e-1)" "unprognostic (7.59e-3)" "prognostic unfavorable (1.46e-4)" "unprognostic (2.90e-1)" "unprognostic (4.23e-3)" "unprognostic (1.10e-2)" "unprognostic (1.07e-1)" "unprognostic (1.11e-2)" "unprognostic (1.28e-3)" "unprognostic (7.81e-3)" "unprognostic (1.73e-1)" "unprognostic (8.11e-2)" "unprognostic (1.46e-1)" 7.1 3.9 0.9 16.9 2.9 23.1 7.0 11.7 3.1 9.1 0.0 6.9 6.6 7.3 3.1 7.7 6.5 6.2 4.8 2.1 6.6 3.0 3.9 7.8 26.2 3.8 4.5 5.6 3.6 4.3 4.5 26.0 5.7 4.5 6.8 7.5 5.6 4.6 5.3 7.9 7.9 8.8 0.3 8.1 6.3 12.4 3.3 20.6 6.3 5.0 24.9 7.3 6.4 10.6 77.0 40.6 49.5 45.8 24.6 24.0 138.8 52.4 43.9 77.5 74.9 50.6 40.8 138.3 33.8 30.0 38.6 46.6 68.4 44.2 68.4 57.5 100.9 181.5 39.5 27.1 9.6 91.5 73.4 11.5 9.3 68.5 24.1 18.4 39.9 37.6 75.0 82.8 63.3 37.6 109.2 50.4 87.5 38.3 76.6 117.1 67.9 77.2 21.5 49.3 64.5 41.5 58.2 26.2 16.5 33.6 28.9 42.2 31.8 111.3 42.2 73.0 84.4 49.6 69.5 166.8 35.0 68.5 87.1 20.3 21.2 5.9 29.8 22.0 25.1 14.2 22.8 20.4 19.3 20.0 25.5 20.5 4.6 42.6 13.8 31.9 21.9 12.6 0.9 2.9 11.7 3.1 2.1 6.6 3.8 4.5 5.7 0.3 3.3 10.6 36.4 6.4 26.5 12.7 38.0 29.6 20.7 26.8 21.1 86.7 32.6 29.6 14.6 7.2 28.2 22.0 56.3 388.1 54.4 29.0 13.7 26.0 46.1 48.1 42.0 38.9 15.7 109.6 17.6 14.3 73.2 33.6 33.6 60.3 37.2 43.6 25.0 14.8 76.8 65.6 22.6 25.5 38.7 31.4 47.8 50.8 28.0 57.9 14.2 15.0 52.5 32.2 123.6 14.6 20.1 21.1 11.3 28.6 73.4 16.3 4.5 9.3 42.8 50.2 13.1 22.6 32.8 229.6 145.3 41.6 22.4 323.7 70.4 38.7 43.1 16.6 DNMT3B ENSG00000088305 "DNA methyltransferase 3 beta" Q9UBC3 20 32762385-32809356 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Activator, DNA-binding, Methyltransferase, Repressor, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 5.3;Extravillous trophoblasts: 5.2;Horizontal cells: 5.0;Inhibitory neurons: 6.8;Sertoli cells: 6.6" "Cancer enriched" "Detected in all" 25 "testis cancer: 111.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 245.7;CACO-2: 95.8;HEL: 100.7;K-562: 98.6;NTERA-2: 333.9;SuSa: 174.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001595, HPA001803, CAB069896" Enhanced Supported Nucleoplasm NA Yes "Cluster 23: Testis - Cell cycle regulation" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "CAB069896: AB_2094115, HPA001595: AB_1847814, HPA001803: " "unprognostic (7.65e-3)" "unprognostic (3.52e-3)" "unprognostic (1.17e-1)" "prognostic unfavorable (5.04e-4)" "unprognostic (3.42e-1)" "unprognostic (7.27e-2)" "unprognostic (4.39e-4)" "unprognostic (4.18e-3)" "unprognostic (8.60e-3)" "unprognostic (8.48e-2)" "unprognostic (6.79e-2)" "unprognostic (4.65e-2)" "prognostic unfavorable (1.87e-7)" "unprognostic (6.62e-2)" "unprognostic (1.00e-1)" "unprognostic (1.50e-1)" "unprognostic (6.55e-2)" 0.8 0.6 1.2 0.8 1.5 3.6 1.3 2.4 1.6 1.3 1.0 0.7 0.8 1.0 3.1 0.8 0.7 0.8 1.0 1.2 1.6 1.7 1.2 0.7 0.9 1.4 1.3 0.8 6.0 1.1 0.6 2.0 1.3 0.8 0.7 3.0 1.2 0.6 0.5 3.8 0.8 0.9 1.0 1.0 0.9 5.8 1.4 3.7 1.7 0.2 0.9 1.3 1.1 1.4 3.9 5.3 27.0 6.2 0.5 2.1 245.7 3.5 2.4 3.6 3.8 95.8 4.3 10.0 9.7 1.7 4.3 2.2 17.6 1.7 3.0 1.2 14.0 100.7 3.3 18.5 0.9 4.6 9.7 2.3 1.9 5.5 1.1 1.8 6.6 6.2 98.6 2.7 1.4 15.7 15.6 86.1 333.9 8.8 3.2 15.4 4.5 2.3 9.1 4.2 8.6 5.7 5.9 8.5 2.5 174.4 5.8 5.5 1.6 5.5 12.3 2.8 2.6 5.9 2.8 3.8 2.6 27.4 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.2 1.5 2.4 1.6 1.2 1.6 1.4 1.3 1.3 1.0 1.4 1.4 1.6 0.0 1.5 3.9 0.1 0.9 0.2 0.3 0.6 2.1 1.5 1.3 1.3 0.0 0.8 0.0 2.1 5.3 0.3 0.2 0.0 1.3 0.1 0.8 0.9 1.6 0.0 4.6 1.1 0.6 5.2 1.2 0.5 2.2 0.0 1.3 0.7 0.6 0.8 5.0 6.8 0.3 0.0 0.3 0.3 1.0 0.0 0.7 0.0 1.9 0.1 0.8 0.0 1.5 1.3 1.0 0.1 0.4 1.3 0.3 0.1 1.3 0.1 2.5 6.6 0.3 0.9 0.1 2.6 0.9 1.3 4.8 0.3 0.8 0.6 0.1 DSCC1 "DCC1, hDCC1, MGC5528" ENSG00000136982 "DNA replication and sister chromatid cohesion 1" Q9BVC3 8 119833976-119855894 "Predicted intracellular proteins" "Cell cycle, DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 9.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 24.6;Extravillous trophoblasts: 17.6;Spermatogonia: 18.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023780, HPA024401" Uncertain Approved Nucleoplasm NA Yes "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA023780: AB_2671311, HPA024401: AB_2671557" "unprognostic (7.36e-3)" "unprognostic (8.24e-2)" "unprognostic (1.56e-1)" "unprognostic (4.71e-3)" "unprognostic (9.91e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (3.92e-6)" "prognostic unfavorable (3.93e-4)" "prognostic unfavorable (5.73e-4)" "unprognostic (3.24e-3)" "unprognostic (8.12e-3)" "unprognostic (2.72e-2)" "unprognostic (2.32e-9)" "unprognostic (2.75e-2)" "unprognostic (5.01e-1)" "unprognostic (4.40e-2)" "unprognostic (8.18e-2)" 1.8 1.8 1.3 3.7 1.6 6.1 2.4 2.1 2.0 2.6 1.1 2.7 2.4 2.4 1.3 2.4 1.5 1.0 1.5 1.4 1.4 0.9 1.1 1.4 7.1 1.5 1.5 1.5 2.8 0.5 0.5 2.3 1.6 1.9 3.5 0.3 3.7 1.2 2.1 2.6 2.3 2.7 1.5 1.3 1.7 2.6 1.4 9.9 1.0 3.4 5.7 1.5 2.1 1.8 34.3 16.6 32.1 29.4 4.6 8.3 13.8 23.1 4.7 16.3 16.9 15.2 20.4 61.7 19.7 6.9 10.1 24.8 36.7 14.4 17.5 42.2 33.3 78.7 16.2 17.9 1.5 31.2 26.4 3.8 2.2 20.1 9.7 3.8 4.7 40.5 27.2 26.9 19.9 33.8 82.4 19.2 47.2 90.4 41.2 29.1 30.4 29.9 12.7 21.3 28.7 17.6 12.4 96.7 15.8 25.0 18.1 17.0 3.2 17.7 48.0 17.2 33.9 36.5 58.2 65.4 9.0 49.2 26.2 0.0 0.0 0.0 0.9 0.0 0.7 0.3 0.2 0.4 0.0 0.1 0.1 0.3 0.0 0.8 0.0 0.2 0.3 0.2 1.3 1.6 2.1 2.0 1.4 1.4 1.5 1.5 1.6 1.5 1.4 1.8 4.7 0.0 0.5 2.6 1.2 3.4 2.2 2.1 4.6 0.7 2.2 3.2 0.8 1.5 0.2 0.0 0.0 7.9 1.6 1.0 0.0 1.6 0.1 0.8 2.8 3.0 0.0 24.6 6.4 2.4 17.6 4.3 1.5 1.3 4.5 3.7 4.6 0.9 4.7 0.0 5.2 1.2 2.0 1.0 1.2 0.2 1.2 0.9 3.6 1.0 0.0 1.5 1.0 7.5 5.3 0.5 0.3 2.6 5.2 1.7 0.2 1.5 1.7 0.3 0.0 2.3 3.3 1.1 18.8 6.0 3.3 1.4 3.0 2.0 3.8 1.5 DSN1 "C20orf172, dJ469A13.2, hKNL-3, KNL3, MIS13" ENSG00000149636 "DSN1 component of MIS12 kinetochore complex" Q9H410 20 36751791-36773818 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 49.8;Spermatocytes: 115.5;Spermatogonia: 75.1;Syncytiotrophoblasts: 47.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002813, HPA030627" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies,Kinetochore,Cytosol" Yes Yes "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli fibrillar center, Nuclear bodies, Kinetochore, Cytosol" "HPA002813: AB_1078343, HPA030627: AB_2732460" "unprognostic (3.60e-2)" "prognostic favorable (4.49e-4)" "unprognostic (5.22e-3)" "unprognostic (1.13e-3)" "unprognostic (2.00e-1)" "unprognostic (4.64e-2)" "prognostic unfavorable (4.16e-5)" "unprognostic (3.93e-1)" "unprognostic (9.35e-2)" "unprognostic (5.51e-2)" "unprognostic (2.98e-2)" "unprognostic (7.66e-2)" "prognostic unfavorable (1.54e-5)" "unprognostic (6.92e-2)" "unprognostic (2.53e-1)" "unprognostic (2.58e-2)" "unprognostic (2.84e-1)" 5.9 9.9 4.2 7.5 4.2 14.3 8.6 3.9 4.5 5.0 5.2 9.2 6.8 4.4 9.3 7.9 4.1 4.4 5.1 4.3 4.4 4.8 9.1 6.3 12.8 4.0 3.9 4.3 4.3 5.5 3.5 8.8 4.1 6.5 10.8 10.7 5.9 6.3 4.0 8.0 7.8 6.3 3.9 9.6 7.3 23.3 4.1 16.4 5.1 4.8 14.3 4.4 4.7 4.7 36.7 29.1 35.7 29.5 14.0 18.0 24.7 42.9 35.1 63.9 70.2 52.5 44.4 39.3 27.4 23.0 69.1 45.8 33.3 32.7 60.3 18.2 22.7 78.3 26.2 36.1 3.0 46.2 34.0 7.0 9.4 43.7 13.8 10.4 31.5 42.4 30.9 33.7 41.7 25.3 59.2 34.5 16.8 63.3 55.1 46.1 109.4 28.4 16.2 20.5 37.8 16.9 52.9 53.7 25.8 26.3 55.9 30.5 16.4 60.1 35.0 56.9 46.1 27.3 39.1 46.4 49.8 40.8 42.6 53.4 6.4 14.5 7.4 11.0 8.4 14.6 8.1 10.3 7.1 18.4 10.1 9.0 11.9 11.1 10.1 46.9 12.2 6.7 4.2 4.2 3.9 4.5 4.3 4.4 4.0 3.9 4.1 3.9 4.1 4.7 6.5 6.4 4.4 1.6 10.3 5.0 11.4 7.6 3.4 8.0 8.7 7.6 5.4 2.8 8.6 5.5 29.2 49.8 9.8 9.2 7.9 6.8 10.6 5.5 5.9 8.1 2.4 22.1 6.3 6.4 30.4 8.4 20.9 9.4 3.8 21.8 7.9 6.2 14.7 6.7 4.4 13.6 4.1 6.3 4.6 8.0 8.7 6.7 1.8 5.6 7.4 6.0 7.2 3.0 3.6 5.1 5.4 7.5 22.9 7.1 7.7 3.6 8.2 17.5 0.0 5.3 8.2 115.5 75.1 12.3 7.2 47.5 7.7 6.9 13.6 11.0 DTL "CDT2, DCAF2, L2DTL, RAMP" ENSG00000143476 "Denticleless E3 ubiquitin protein ligase homolog" Q9NZJ0 1 212035553-212107400 "Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA replication, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 14.6;intestine: 4.7;lymphoid tissue: 14.2;placenta: 3.9;testis: 13.7" "Cell type enhanced" "Detected in many" "Early spermatids: 25.3;Erythroid cells: 36.2;Extravillous trophoblasts: 16.2;Spermatocytes: 53.2;Spermatogonia: 20.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 2.0" "Lineage enriched" "Detected in single" 8 "T-cells: 2.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028016, HPA032023, HPA032031" Supported Supported Nucleoplasm,Nucleoli,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli, Cytosol" "HPA028016: AB_10611958, HPA032023: AB_2674114, HPA032031: AB_2674119" "unprognostic (7.61e-2)" "unprognostic (1.01e-3)" "unprognostic (2.14e-2)" "unprognostic (3.05e-2)" "unprognostic (2.19e-1)" "unprognostic (5.31e-2)" "prognostic unfavorable (4.41e-5)" "unprognostic (8.96e-3)" "unprognostic (2.45e-3)" "unprognostic (8.83e-3)" "unprognostic (2.52e-3)" "unprognostic (2.83e-2)" "prognostic unfavorable (1.71e-9)" "unprognostic (5.93e-2)" "unprognostic (2.01e-1)" "unprognostic (1.96e-2)" "unprognostic (2.82e-1)" 0.6 0.2 0.0 4.1 0.0 14.6 1.9 0.0 0.1 0.6 0.0 3.3 2.3 1.1 0.1 1.9 0.4 0.4 0.1 0.0 0.0 0.1 1.2 1.4 5.6 0.0 0.1 0.1 0.1 0.5 0.2 3.9 0.0 0.4 4.7 0.0 0.4 0.1 0.1 2.1 3.0 1.9 0.0 2.5 1.3 13.7 0.1 14.2 0.5 0.0 6.4 1.2 0.7 0.0 34.1 28.1 48.0 23.6 2.9 5.8 23.3 41.3 25.5 38.1 56.1 17.6 29.0 25.2 15.4 16.1 25.0 25.8 62.5 34.9 54.7 31.4 30.9 40.7 33.6 21.5 0.1 54.1 25.3 2.5 1.2 62.2 32.4 6.8 17.7 44.7 49.1 51.1 44.4 13.5 75.3 24.3 56.6 25.2 32.9 57.2 84.0 49.2 11.6 22.9 29.6 46.0 39.2 37.5 17.6 47.7 32.0 24.1 9.7 38.2 28.6 40.5 47.8 18.4 30.5 57.7 19.1 35.5 37.8 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.3 0.5 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 2.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 2.3 2.3 0.4 1.7 0.0 0.0 1.3 1.3 7.0 1.5 0.9 0.0 0.0 12.8 1.4 1.5 0.0 0.4 25.3 0.4 1.3 5.2 0.0 36.2 0.2 0.0 16.2 2.4 3.1 1.0 0.0 11.4 0.7 0.4 4.7 0.0 0.3 3.3 0.0 0.3 0.8 12.4 1.2 2.2 0.0 1.0 0.2 0.0 0.0 0.0 0.1 0.6 0.4 0.0 12.8 0.2 0.6 0.0 0.1 0.0 0.0 0.2 2.7 53.2 20.8 5.6 1.7 1.5 2.6 1.6 5.2 0.7 DTX2 "KIAA1528, RNF58" ENSG00000091073 "Deltex E3 ubiquitin ligase 2" Q86UW9 7 76461676-76505995 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 54.0" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 87.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 67.7;CAPAN-2: 110.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042931 Approved Supported "Nucleoplasm,Nuclear membrane" NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Nuclear membrane" "HPA042931: AB_2678227" "unprognostic (1.72e-1)" "unprognostic (1.73e-1)" "unprognostic (1.62e-2)" "unprognostic (1.58e-2)" "prognostic unfavorable (8.47e-4)" "unprognostic (2.85e-2)" "unprognostic (1.28e-3)" "unprognostic (7.54e-2)" "unprognostic (4.76e-2)" "unprognostic (2.28e-2)" "unprognostic (2.10e-2)" "unprognostic (6.56e-2)" "prognostic unfavorable (1.13e-8)" "unprognostic (2.87e-2)" "unprognostic (1.53e-1)" "unprognostic (1.50e-1)" "unprognostic (1.19e-2)" 10.0 5.0 5.6 12.3 6.3 5.1 10.3 3.3 10.1 17.4 13.8 15.8 10.2 9.3 1.1 54.0 10.5 9.3 6.8 4.3 5.9 5.4 8.7 10.3 10.9 11.1 8.1 8.1 10.5 8.4 6.7 5.3 8.1 13.7 8.1 4.4 30.4 3.9 12.5 31.0 13.3 4.3 3.8 13.3 14.2 28.1 13.5 9.0 7.9 2.7 10.1 12.1 27.2 12.8 31.8 67.7 9.9 14.7 5.5 5.4 21.2 6.8 5.7 7.2 9.9 19.1 110.9 9.8 4.7 6.8 38.1 23.2 5.3 32.1 4.5 22.1 11.3 5.6 14.4 16.9 7.4 8.2 13.7 9.6 19.1 18.7 10.0 5.6 5.5 17.2 17.3 14.3 8.8 15.3 12.6 28.6 14.4 23.8 10.2 13.8 9.1 17.7 3.4 24.4 3.9 8.2 10.9 18.4 9.3 8.6 18.5 21.6 5.8 40.5 19.0 13.8 27.1 10.7 13.7 11.2 8.8 8.8 21.3 17.7 11.6 17.2 8.6 13.3 6.2 6.6 7.1 8.5 10.1 7.3 7.1 7.9 22.8 4.2 18.8 17.8 11.0 8.4 5.6 6.3 3.3 10.1 4.3 5.9 11.1 8.1 8.1 3.8 13.5 12.8 7.3 6.4 5.0 5.2 13.1 33.9 19.5 87.2 23.3 2.6 7.1 4.8 2.3 4.3 59.2 7.3 8.4 18.5 12.0 39.1 3.9 19.4 33.0 8.1 3.1 5.9 9.1 3.8 5.7 10.8 13.5 6.5 61.2 10.7 3.8 3.2 7.1 4.3 21.6 3.3 5.2 25.6 22.4 11.0 7.7 10.4 5.6 14.5 7.2 19.7 10.0 5.7 8.2 18.1 10.0 23.1 37.9 4.9 13.9 20.0 21.0 3.2 62.8 9.2 6.6 3.0 7.3 11.0 11.0 27.0 35.4 37.6 9.7 1.9 26.1 62.5 DUSP1 "CL100, HVH1, MKP-1, PTPN10" ENSG00000120129 "Dual specificity phosphatase 1" P28562 5 172768096-172771195 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Stress response" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 2357.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 7426.8" "Lineage enriched" "Detected in all" 9 "granulocytes: 7426.8" "Cell line enhanced" "Detected in all" "HHSteC: 201.0;hTCEpi: 359.3;REH: 202.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069577 Approved Nucleoli,Cytosol NA Yes "Cluster 50: Neutrophils - Cellular senescence" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" Nucleoli Cytosol "HPA069577: AB_2686156" "unprognostic (1.51e-1)" "unprognostic (1.24e-1)" "unprognostic (9.73e-2)" "unprognostic (8.17e-2)" "unprognostic (4.64e-1)" "unprognostic (1.58e-3)" "unprognostic (4.18e-2)" "unprognostic (6.94e-2)" "unprognostic (3.11e-1)" "unprognostic (1.43e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-2)" "unprognostic (2.76e-2)" "prognostic unfavorable (3.11e-5)" "unprognostic (2.69e-1)" "unprognostic (2.35e-2)" "unprognostic (1.41e-3)" 922.6 515.4 84.9 364.9 85.8 692.4 586.1 134.8 121.1 501.3 134.7 336.1 66.0 382.3 42.0 526.6 677.4 570.5 395.3 79.4 114.6 281.2 721.3 719.9 178.6 132.0 90.3 541.2 240.1 116.5 319.5 297.3 104.1 438.5 228.5 202.7 350.3 356.9 251.8 1054.1 170.3 452.7 123.7 304.7 396.0 68.1 115.4 131.3 612.9 451.3 56.2 778.1 610.0 121.2 10.7 26.5 8.2 11.5 175.6 102.2 14.0 170.3 49.3 111.9 45.0 29.2 12.4 3.5 48.6 120.4 128.1 4.7 8.1 42.3 52.1 95.8 22.4 2.3 63.1 12.6 201.0 1.2 3.8 98.1 359.3 50.9 82.1 58.2 35.6 7.4 9.0 66.1 73.1 12.6 5.7 5.0 7.4 8.2 7.7 202.2 15.3 32.3 80.2 5.4 35.5 14.9 46.2 76.9 6.3 34.1 6.7 1.9 94.1 79.1 39.8 77.8 13.4 13.6 8.4 3.1 70.3 1.8 3.3 931.4 584.5 1640.7 85.0 589.2 212.6 57.6 75.6 88.6 263.4 54.1 35.9 40.7 7426.8 114.5 791.6 14.3 68.1 409.9 84.9 85.8 134.8 121.1 79.4 114.6 132.0 90.3 104.1 123.7 115.4 121.2 1856.5 410.3 341.0 23.8 918.4 1279.8 1140.5 456.9 1810.4 73.0 464.2 567.7 211.3 739.2 243.1 211.5 27.1 316.2 618.9 633.7 56.7 335.9 71.6 531.6 990.9 870.4 715.5 193.5 11.9 88.7 407.2 1367.4 597.3 1013.7 301.1 175.8 781.4 345.7 1043.0 48.8 13.4 891.8 207.5 1525.5 2357.3 40.3 384.9 1965.5 542.5 66.5 173.3 1159.3 33.0 6.6 4.1 226.3 683.3 311.1 952.2 685.7 736.1 35.5 218.0 190.5 769.2 720.7 671.9 12.9 24.6 1996.9 1956.6 582.0 1015.2 223.4 415.8 676.6 DUSP11 PIR1 ENSG00000144048 "Dual specificity phosphatase 11" O75319 2 73762184-73780157 "Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021052 Supported "Nucleoplasm,Nucleoli fibrillar center,Cytokinetic bridge" Yes Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Nucleoli fibrillar center" "Cytokinetic bridge" "HPA021052: AB_2670577" "unprognostic (2.45e-3)" "unprognostic (1.06e-1)" "unprognostic (2.19e-2)" "unprognostic (7.87e-3)" "unprognostic (9.14e-2)" "unprognostic (5.28e-3)" "prognostic unfavorable (2.10e-7)" "unprognostic (7.20e-2)" "unprognostic (5.43e-2)" "unprognostic (5.85e-2)" "unprognostic (8.67e-3)" "unprognostic (3.84e-2)" "unprognostic (7.56e-3)" "unprognostic (1.41e-1)" "unprognostic (1.47e-1)" "unprognostic (1.47e-3)" "unprognostic (1.46e-1)" 16.0 13.3 7.9 17.1 7.7 35.2 20.4 13.4 11.2 22.4 7.6 16.0 17.3 21.2 19.3 30.5 39.0 15.9 14.2 8.1 6.9 20.2 17.9 14.3 25.3 6.1 5.7 23.5 11.0 14.7 14.0 20.5 6.1 16.5 17.4 8.3 16.0 14.4 14.3 27.6 15.3 19.6 4.8 19.0 16.3 16.8 6.5 24.8 16.5 17.8 26.1 25.2 22.4 8.3 39.4 16.7 17.6 18.6 31.2 38.7 31.2 28.2 36.7 35.8 36.4 24.2 29.1 50.6 17.7 30.6 32.1 26.7 22.0 56.8 34.3 35.2 22.9 31.2 12.0 37.3 32.7 35.5 28.0 31.6 67.3 32.1 44.1 31.1 40.4 24.2 33.6 28.6 40.2 21.3 34.3 37.6 28.4 36.7 22.7 13.6 47.3 46.0 29.3 32.1 25.9 14.1 26.1 30.6 35.7 21.0 16.4 18.6 23.1 25.4 31.4 29.5 33.7 30.7 26.2 68.1 23.5 35.5 25.3 72.5 42.2 99.5 56.3 39.3 73.5 68.3 65.8 67.4 47.3 65.9 69.4 65.5 65.2 69.8 40.6 35.7 88.6 71.7 7.9 7.7 13.4 11.2 8.1 6.9 6.1 5.7 6.1 4.8 6.5 8.3 26.5 9.6 12.0 7.5 39.5 83.2 55.1 93.0 39.3 11.0 12.9 15.1 8.6 27.1 45.7 12.9 4.2 32.8 34.8 15.5 50.9 29.6 9.1 18.0 15.7 34.6 12.0 21.0 14.9 27.3 42.0 26.5 16.3 13.6 40.7 20.5 52.1 15.3 30.7 5.0 12.7 18.0 36.7 20.2 27.1 7.0 28.9 17.0 23.2 10.3 34.8 9.8 41.2 13.0 13.8 28.2 17.8 25.6 31.8 30.0 22.8 50.4 38.2 16.6 6.6 18.2 23.1 23.8 34.6 42.8 83.0 38.6 39.8 20.7 18.8 60.9 DUSP14 "MKP-L, MKP6" ENSG00000276023 "Dual specificity phosphatase 14" O95147 17 37489891-37513501 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 44.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 179.7;Basal prostatic cells: 239.3;Cytotrophoblasts: 162.8;Endometrial ciliated cells: 146.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HBF TERT88: 36.4;SuSa: 24.9;WM-115: 37.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019911 Approved Approved Nucleoplasm,Cytosol NA Yes 79000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" "HPA019911: AB_1847888" "unprognostic (1.32e-1)" "unprognostic (3.06e-1)" "unprognostic (2.19e-2)" "unprognostic (1.57e-1)" "unprognostic (4.60e-1)" "unprognostic (3.22e-2)" "unprognostic (3.43e-3)" "unprognostic (2.02e-3)" "unprognostic (2.18e-1)" "unprognostic (2.59e-1)" "unprognostic (7.02e-3)" "unprognostic (3.81e-1)" "prognostic unfavorable (6.97e-9)" "unprognostic (7.93e-2)" "unprognostic (1.97e-1)" "unprognostic (1.73e-1)" "unprognostic (1.41e-3)" 15.3 14.2 10.9 1.3 11.2 0.3 12.4 11.2 17.0 12.8 10.9 10.3 0.0 9.5 5.5 17.4 7.5 1.2 14.1 11.0 10.9 8.7 15.2 8.6 0.4 11.9 11.1 5.6 6.6 1.0 14.5 0.9 10.6 6.4 1.0 9.9 13.1 0.3 11.0 44.1 5.5 0.8 10.4 2.8 7.6 13.7 10.8 4.4 23.1 4.4 2.7 7.2 17.1 10.7 2.6 0.2 4.9 2.1 0.1 0.6 2.1 10.4 7.8 14.3 15.6 1.2 17.9 0.2 0.9 7.6 0.2 2.8 0.2 6.1 36.4 0.2 0.7 0.0 1.6 6.2 1.5 0.5 3.0 8.5 5.5 4.8 2.5 10.2 0.3 0.2 0.6 3.1 11.4 0.4 9.7 1.7 0.3 3.8 0.0 2.5 0.6 2.5 17.5 2.4 1.9 0.3 0.5 17.6 4.1 24.9 0.8 3.9 1.4 10.8 5.8 0.1 5.8 0.1 0.3 0.1 0.1 0.0 37.5 1.1 0.0 0.7 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.7 1.6 0.0 0.2 0.0 0.0 0.2 10.9 11.2 11.2 17.0 11.0 10.9 11.9 11.1 10.6 10.4 10.8 10.7 15.0 6.4 5.4 2.9 8.3 179.7 239.3 74.8 129.1 6.8 42.6 46.0 15.0 4.3 39.6 7.3 8.4 162.8 16.6 0.3 29.4 34.8 36.4 146.9 18.5 21.7 2.4 11.4 12.0 15.1 82.1 30.2 3.1 85.3 87.0 10.6 14.6 15.7 19.7 15.2 5.3 1.2 36.7 2.8 34.8 52.5 13.7 5.9 62.2 4.7 25.3 16.1 15.5 3.0 3.3 74.8 2.9 6.0 9.9 64.9 0.1 16.9 61.3 24.5 0.0 13.2 45.2 26.0 33.4 44.0 92.6 67.9 18.2 26.3 1.1 67.0 DUT dUTPase ENSG00000128951 "Deoxyuridine triphosphatase" P33316 15 48331011-48343373 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 508.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054422, HPA060360" Enhanced Supported Nucleoplasm No Yes 31000 "Cluster 26: Non-specific - Mitochondria" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA054422: AB_2682483, HPA060360: AB_2684262" "unprognostic (1.82e-1)" "unprognostic (3.49e-2)" "unprognostic (7.89e-2)" "unprognostic (5.27e-2)" "unprognostic (2.20e-1)" "unprognostic (7.17e-2)" "unprognostic (1.65e-1)" "unprognostic (1.16e-2)" "unprognostic (4.42e-3)" "unprognostic (1.87e-2)" "unprognostic (4.25e-1)" "unprognostic (3.54e-2)" "unprognostic (3.68e-2)" "unprognostic (4.23e-2)" "unprognostic (1.47e-1)" "unprognostic (2.09e-2)" "unprognostic (1.71e-2)" 73.0 65.3 54.7 61.7 58.9 162.9 76.4 57.1 77.2 90.7 60.0 69.5 29.3 76.9 49.7 72.1 77.6 33.6 68.9 53.9 59.6 67.6 53.6 58.1 97.8 58.2 55.5 86.1 53.2 48.3 80.0 45.1 58.3 77.8 47.1 49.1 66.5 48.3 57.9 71.6 66.5 40.4 57.7 82.1 61.5 57.3 57.5 111.4 89.2 53.0 87.8 69.1 78.0 63.5 196.1 60.2 143.9 137.1 98.4 104.0 85.3 202.1 128.1 182.8 224.6 69.8 131.0 539.3 106.0 112.0 149.4 262.1 152.4 138.4 177.6 383.4 157.2 442.2 151.8 96.1 54.8 469.0 202.0 64.4 92.1 123.9 65.0 117.8 123.3 316.6 244.0 297.6 136.5 79.3 422.4 548.7 90.7 197.4 114.5 338.6 313.9 570.0 120.8 130.4 207.2 210.1 150.0 119.6 184.4 145.5 169.6 368.6 103.0 190.1 183.1 228.3 269.7 238.1 534.3 532.5 143.6 789.4 213.4 32.5 50.3 46.8 52.9 53.1 68.7 94.8 94.7 84.6 74.0 90.0 97.4 64.3 30.9 60.5 68.4 85.3 94.3 71.4 54.7 58.9 57.1 77.2 53.9 59.6 58.2 55.5 58.3 57.7 57.5 63.5 153.6 54.5 38.9 39.8 126.8 179.6 212.0 222.4 131.5 48.3 158.0 205.5 120.1 95.8 118.5 104.8 14.6 221.8 103.9 62.8 203.5 94.3 36.8 67.2 123.5 123.0 96.1 418.8 36.5 46.5 286.8 147.9 76.5 86.0 84.4 118.3 101.4 77.6 174.5 82.4 32.1 98.4 105.8 87.7 112.6 31.5 184.8 92.0 154.7 23.4 89.5 106.3 95.8 23.6 45.1 45.4 58.8 177.6 192.3 133.2 27.2 256.4 59.6 40.9 157.8 167.1 154.0 508.7 270.0 206.4 168.5 97.1 124.4 82.3 195.4 181.2 DYNC2I2 "bA216B9.3, CFAP133, DIC5, FAP133, MGC20486, WDR34" ENSG00000119333 "Dynein 2 intermediate chain 2" Q96EX3 9 128633653-128656847 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 20.4;Cytotrophoblasts: 89.8;Extravillous trophoblasts: 95.3;Hofbauer cells: 21.9;Syncytiotrophoblasts: 37.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 35.8;naive B-cell: 52.9" "Lineage enriched" "Detected in all" 5 "B-cells: 52.9" "Cell line enhanced" "Detected in all" "MCF7: 432.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040764, HPA041091" Approved Approved Cytosol NA Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 71: Testis - DNA repair" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "HPA040764: AB_10795625, HPA041091: AB_10796237" "unprognostic (1.45e-1)" "prognostic favorable (1.63e-4)" "unprognostic (2.55e-1)" "prognostic favorable (7.01e-5)" "unprognostic (2.27e-1)" "unprognostic (7.00e-3)" "prognostic unfavorable (8.79e-4)" "unprognostic (6.04e-2)" "unprognostic (4.39e-1)" "unprognostic (3.65e-1)" "unprognostic (8.55e-2)" "unprognostic (1.04e-1)" "unprognostic (3.57e-3)" "unprognostic (2.06e-2)" "unprognostic (1.68e-1)" "unprognostic (1.12e-1)" "unprognostic (1.28e-1)" 14.4 49.9 15.7 11.4 15.4 33.2 20.1 14.3 20.1 28.2 30.5 26.7 22.2 22.4 8.9 37.9 30.5 11.1 41.4 15.4 18.9 61.8 39.1 25.1 12.0 17.0 19.4 19.1 36.7 21.2 36.1 11.0 16.4 31.0 10.3 4.5 31.9 14.0 11.1 24.0 27.7 6.3 16.5 23.6 26.3 69.8 16.6 23.8 55.6 4.3 9.5 19.2 23.7 14.7 112.7 202.8 49.8 78.8 11.4 16.1 141.4 46.2 32.9 66.5 42.8 96.6 197.3 40.4 32.4 30.8 62.0 169.4 47.5 50.8 16.6 93.5 40.1 24.0 134.8 52.0 13.9 41.5 39.4 8.0 25.0 66.3 18.9 24.0 46.5 112.6 83.5 34.0 36.4 432.4 151.3 106.1 63.7 97.3 121.0 157.2 66.6 136.8 42.1 36.0 125.1 100.1 143.9 135.9 36.8 13.7 230.5 40.7 28.3 75.9 114.8 95.6 90.7 34.6 100.7 39.6 71.4 41.9 74.0 1.7 1.1 0.4 1.4 1.6 2.3 35.8 2.9 3.9 2.8 52.9 1.1 1.7 0.8 4.5 5.7 11.0 5.7 3.8 15.7 15.4 14.3 20.1 15.4 18.9 17.0 19.4 16.4 16.5 16.6 14.7 2.7 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 89.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 95.3 6.0 0.0 0.0 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 37.4 0.2 0.0 0.0 0.0 DYNLL1 "DLC1, DLC8, DNCL1, hdlc1, LC8, PIN" ENSG00000088986 "Dynein light chain LC8-type 1" P63167 12 120469850-120498493 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Transcription, Transcription regulation, Transport" "Activator, Motor protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 4098.6;Respiratory ciliated cells: 2679.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039954 Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA Yes 890000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 27: Brain & Skin - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA039954: AB_2676771" "unprognostic (1.94e-1)" "unprognostic (1.08e-1)" "unprognostic (3.43e-2)" "unprognostic (2.88e-2)" "unprognostic (5.63e-2)" "unprognostic (7.09e-2)" "prognostic unfavorable (7.33e-5)" "unprognostic (4.41e-3)" "unprognostic (4.64e-2)" "unprognostic (6.17e-3)" "unprognostic (1.61e-2)" "unprognostic (9.10e-2)" "prognostic unfavorable (7.97e-7)" "unprognostic (4.91e-2)" "unprognostic (2.80e-2)" "unprognostic (7.91e-2)" "unprognostic (1.62e-1)" 268.6 261.9 912.5 186.7 967.7 126.8 268.0 895.2 1292.9 354.2 894.7 325.8 162.8 319.4 322.3 719.9 544.2 242.7 257.5 975.4 944.7 352.6 238.4 222.6 241.6 896.1 898.5 247.0 225.1 228.2 309.7 259.2 914.2 225.9 327.4 181.3 245.4 264.6 85.6 626.7 206.3 390.1 935.1 185.2 244.5 360.3 909.7 306.5 176.1 163.9 357.8 389.8 474.4 1001.2 721.6 811.4 779.2 600.8 677.1 713.6 250.8 968.0 451.6 785.6 466.7 770.8 472.3 400.6 510.3 945.1 753.0 629.6 949.3 818.3 781.0 528.3 617.9 390.4 532.9 1062.5 676.2 412.8 620.5 436.2 863.0 584.6 477.5 855.7 831.8 421.5 502.0 446.1 1056.8 960.1 541.4 894.8 642.2 917.7 935.7 543.0 403.0 499.2 1143.1 659.8 535.2 392.0 789.3 677.7 926.6 812.6 673.6 595.3 635.2 592.3 502.1 525.6 852.2 264.0 562.8 404.6 656.8 645.1 776.6 516.6 291.9 384.2 200.6 303.3 155.3 310.4 207.2 211.7 281.8 219.0 132.0 165.7 50.1 282.9 334.8 461.6 373.5 353.0 912.5 967.7 895.2 1292.9 975.4 944.7 896.1 898.5 914.2 935.1 909.7 1001.2 810.1 195.5 101.9 79.3 341.4 922.2 359.1 1275.0 356.8 138.4 800.0 949.4 170.8 303.1 764.6 399.1 83.4 524.6 484.1 689.9 1113.2 691.2 1407.2 1842.5 528.5 541.9 480.8 332.9 111.2 538.9 897.4 538.5 240.5 488.1 316.7 611.9 521.9 499.0 732.1 85.8 62.8 801.6 1121.0 329.4 706.1 4098.6 516.6 466.3 595.9 42.2 701.6 164.0 248.2 47.3 156.4 754.9 798.6 701.8 234.9 304.7 533.4 1125.0 2679.6 193.5 368.1 440.7 1016.3 961.5 721.4 1005.4 1610.1 1006.6 396.6 586.3 498.2 389.6 DYNLT1 TCTEL1 ENSG00000146425 "Dynein light chain Tctex-type 1" P63172 6 158636474-158644743 "Predicted intracellular proteins" "Cell cycle, Cell division, Cytoplasmic inwards viral transport, Host-virus interaction, Microtubular inwards viral transport, Mitosis, Neurogenesis, Transport, Virus entry into host cell" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 946.1;Ionocytes: 830.0;Respiratory ciliated cells: 1335.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046559 Approved Nucleoplasm NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 1: Thyroid gland - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA046559: AB_2679698" "unprognostic (1.80e-3)" "unprognostic (3.09e-1)" "unprognostic (3.69e-2)" "unprognostic (2.22e-3)" "unprognostic (5.31e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (5.62e-2)" "unprognostic (1.83e-1)" "unprognostic (3.07e-2)" "unprognostic (1.43e-1)" "unprognostic (9.58e-2)" "unprognostic (2.72e-3)" "unprognostic (2.61e-1)" "unprognostic (1.74e-1)" "unprognostic (4.73e-2)" "unprognostic (2.92e-2)" 80.8 114.4 65.9 71.2 66.6 40.7 114.7 69.4 87.5 109.8 83.8 126.9 109.3 100.5 144.2 155.3 165.3 84.6 131.1 64.7 71.0 171.2 100.6 96.6 62.8 73.1 72.2 79.6 52.8 115.1 72.4 81.1 72.6 101.8 129.6 34.3 99.5 115.1 125.3 52.4 123.2 164.5 70.7 80.7 90.7 129.3 67.6 54.3 119.7 94.9 84.7 127.8 98.8 75.1 188.4 130.6 211.8 208.2 214.3 216.7 87.3 190.6 152.7 229.9 270.2 155.8 165.5 45.1 77.5 398.0 172.7 169.1 134.4 205.6 277.5 64.3 187.2 71.2 115.8 182.7 225.4 33.4 48.1 187.9 217.5 190.0 188.8 198.7 295.1 62.2 139.0 52.4 342.4 166.7 14.9 86.6 116.0 336.5 106.0 29.7 113.9 41.3 323.7 126.9 421.7 211.1 268.1 216.7 83.0 178.8 147.7 73.6 258.9 113.6 143.9 123.2 174.8 31.6 42.2 75.7 161.6 136.9 125.9 158.9 383.6 39.2 106.0 374.8 119.5 76.4 112.7 122.1 192.6 51.7 93.8 96.8 681.1 92.4 290.9 93.4 146.0 254.2 65.9 66.6 69.4 87.5 64.7 71.0 73.1 72.2 72.6 70.7 67.6 75.1 91.4 96.1 96.1 7.5 56.7 54.0 253.2 946.1 62.0 16.9 186.0 206.5 150.7 160.2 610.7 211.5 12.5 227.8 84.5 227.3 416.7 422.0 137.3 710.6 152.7 107.3 172.6 43.7 16.4 274.4 197.9 124.8 86.2 271.7 60.8 137.7 116.4 93.6 155.1 23.5 19.4 238.6 830.0 108.7 67.9 68.4 107.8 126.1 113.8 13.1 201.3 114.1 143.2 16.1 19.3 451.4 317.4 127.9 51.8 291.4 379.8 661.2 1335.9 42.0 138.1 55.2 241.5 452.0 177.7 172.3 61.1 215.1 106.8 187.5 168.6 443.0 E2F1 "RBBP3, RBP3" ENSG00000101412 "E2F transcription factor 1" Q01094 20 33675477-33686385 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 25.0;Granulosa cells: 11.4;Spermatogonia: 32.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000329, HPA008003, CAB019308, HPA029735" Enhanced Supported Nucleoplasm,Centrosome NA Yes "Cluster 22: NK-cells - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Centrosome" "CAB000329: AB_627476, CAB019308: , HPA008003: AB_1847936, HPA029735: AB_2673176" "unprognostic (7.46e-2)" "prognostic favorable (9.22e-6)" "unprognostic (2.11e-2)" "prognostic unfavorable (4.33e-5)" "unprognostic (1.51e-1)" "unprognostic (1.21e-2)" "prognostic unfavorable (3.83e-5)" "unprognostic (1.25e-2)" "unprognostic (8.23e-2)" "unprognostic (9.66e-2)" "prognostic unfavorable (4.18e-4)" "unprognostic (3.15e-2)" "prognostic unfavorable (8.99e-5)" "unprognostic (1.05e-2)" "unprognostic (7.50e-2)" "prognostic favorable (1.62e-4)" "unprognostic (1.91e-1)" 1.8 5.5 7.1 5.6 7.1 34.3 1.6 5.2 9.2 1.8 3.9 3.8 3.2 1.2 0.2 5.7 1.3 0.7 1.4 6.1 5.6 0.9 1.8 3.7 8.7 7.6 6.4 3.5 1.0 1.3 0.6 2.4 6.5 1.9 3.9 0.7 1.9 0.9 1.6 4.7 4.1 2.8 7.0 5.0 3.7 10.4 6.9 10.7 0.8 0.8 6.9 2.4 2.5 8.3 48.1 45.4 52.0 40.5 5.2 3.6 39.3 45.0 21.4 55.9 46.7 81.1 48.0 87.3 44.2 20.2 67.7 35.4 25.3 23.8 24.8 26.4 36.5 71.6 71.9 47.7 0.4 34.0 43.6 2.8 1.4 30.6 5.4 5.7 14.6 54.4 19.3 60.0 34.9 42.3 72.8 71.6 15.6 47.9 64.6 71.4 140.7 36.2 9.6 28.7 76.7 54.1 54.6 37.6 22.7 14.8 47.3 42.4 7.9 65.0 37.7 45.8 64.8 58.1 42.0 72.6 54.1 20.0 39.3 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.4 1.0 0.1 0.1 0.1 7.1 7.1 5.2 9.2 6.1 5.6 7.6 6.4 6.5 7.0 6.9 8.3 1.1 0.0 1.1 0.7 3.6 2.9 1.7 0.5 0.0 2.3 3.1 4.3 0.4 0.0 1.4 0.0 0.0 5.0 2.9 2.4 0.0 0.9 1.0 0.3 1.0 1.6 0.0 25.0 1.5 0.2 9.6 3.0 7.7 1.2 0.0 11.4 0.7 0.8 4.4 0.0 0.5 4.6 2.0 0.6 2.1 3.1 2.1 3.1 1.8 1.0 0.1 1.5 1.0 1.0 3.4 0.6 0.5 1.2 9.7 0.5 1.4 0.1 0.2 2.3 0.0 1.0 3.0 7.5 32.9 3.7 1.7 1.8 3.3 1.2 7.0 3.5 E2F2 E2F-2 ENSG00000007968 "E2F transcription factor 2" Q14209 1 23506438-23531233 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 25.1;esophagus: 8.7;lymphoid tissue: 15.8" "Group enriched" "Detected in many" 4 "Early spermatids: 50.2;Erythroid cells: 45.7;Late spermatids: 110.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 4.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 46.7;Karpas-707: 38.9;U-266/84: 37.2;U-698: 38.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" CAB016313 Uncertain NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" "CAB016313: AB_2096794" "unprognostic (3.14e-2)" "unprognostic (5.74e-3)" "unprognostic (1.31e-3)" "unprognostic (4.18e-2)" "unprognostic (8.54e-2)" "unprognostic (1.70e-3)" "unprognostic (6.43e-6)" "unprognostic (7.83e-3)" "unprognostic (1.53e-2)" "unprognostic (7.33e-2)" "unprognostic (1.51e-3)" "unprognostic (1.86e-2)" "unprognostic (0.00e+0)" "unprognostic (1.00e-3)" "unprognostic (2.82e-1)" "unprognostic (8.67e-3)" "unprognostic (1.84e-1)" 0.2 0.2 0.0 1.8 0.0 25.1 0.1 0.1 0.1 0.9 0.1 3.4 1.5 0.1 0.0 8.7 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.8 3.2 0.0 0.1 0.0 0.1 0.0 0.0 0.8 0.1 0.1 2.1 0.0 0.8 0.0 0.1 3.5 2.1 0.3 0.0 5.1 0.7 3.6 0.1 15.8 0.2 0.0 3.7 0.3 1.9 0.1 5.4 3.9 6.4 10.2 0.2 0.2 4.5 2.5 1.2 2.4 3.1 2.5 3.1 46.7 3.0 1.3 1.1 10.6 12.9 0.6 2.2 11.8 4.2 7.4 10.7 2.8 0.0 5.4 9.3 0.0 0.1 1.7 0.2 0.3 0.7 21.4 5.8 38.9 1.1 3.2 24.3 5.0 1.4 5.8 1.9 26.4 13.7 15.7 0.9 1.4 8.3 11.6 4.3 5.4 1.3 0.8 4.0 3.9 0.5 2.2 6.1 7.0 3.6 28.5 37.2 38.0 2.1 5.8 4.3 4.1 0.2 0.8 0.0 0.6 0.0 0.4 0.3 0.2 0.5 0.3 0.0 0.0 0.1 0.1 0.9 0.4 1.3 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 3.4 0.8 0.2 0.2 1.8 0.0 1.0 1.3 0.6 0.0 0.3 1.8 0.0 3.4 0.7 14.5 0.0 0.1 50.2 0.3 0.3 0.6 1.2 45.7 0.1 0.0 4.8 1.1 3.1 1.1 0.0 4.2 0.4 0.4 2.3 0.0 0.1 5.9 0.0 3.1 0.8 110.3 0.3 2.7 0.0 1.0 1.4 0.0 0.0 0.5 0.1 0.1 7.3 0.4 14.5 0.6 1.8 0.1 0.0 0.0 0.0 0.1 0.8 2.5 5.2 10.2 1.0 0.5 1.7 0.7 9.5 1.3 EBP "CDPX2, CHO2, CPX, CPXD" ENSG00000147155 "EBP cholestenol delta-isomerase" Q15125 X 48521799-48528716 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Isomerase "Cataract, Disease variant, Dwarfism, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 328.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 674.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003130 Approved Supported "Endoplasmic reticulum" NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "HPA003130: AB_1078717" "unprognostic (1.90e-1)" "unprognostic (2.64e-2)" "unprognostic (2.80e-1)" "unprognostic (6.27e-2)" "unprognostic (3.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.13e-1)" "unprognostic (1.15e-1)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" "unprognostic (4.72e-2)" "unprognostic (1.47e-1)" "unprognostic (5.14e-2)" "unprognostic (4.04e-2)" "unprognostic (5.39e-2)" "unprognostic (4.13e-1)" "unprognostic (1.36e-1)" 10.2 73.3 16.7 17.1 17.2 48.3 17.4 18.5 17.8 19.4 22.0 50.6 85.5 11.0 17.3 41.3 14.3 10.5 32.5 16.8 18.7 44.0 328.5 24.4 18.8 24.4 16.6 12.7 26.0 44.0 7.2 8.2 24.2 40.6 57.5 10.7 25.0 11.7 9.5 27.8 54.2 14.9 15.8 16.9 31.6 14.2 15.9 28.2 14.4 10.6 32.7 14.1 23.3 16.0 224.5 96.4 107.4 77.0 74.5 39.2 50.5 48.2 43.6 64.3 93.9 169.9 382.7 115.9 35.2 41.3 83.5 230.3 217.5 293.8 49.8 85.8 149.7 50.1 115.2 139.3 57.8 179.2 138.2 51.3 108.6 112.9 86.4 22.5 46.5 98.1 77.6 119.5 50.7 163.7 119.1 199.9 118.2 88.3 199.1 93.8 10.3 363.7 175.6 68.8 110.0 59.6 175.4 122.6 31.2 91.5 122.9 71.1 46.6 33.1 56.2 132.9 63.1 47.5 72.1 107.7 78.7 239.7 40.6 96.1 37.7 97.1 129.4 53.4 104.5 71.5 90.5 116.7 53.5 57.2 76.5 99.7 7.3 63.9 57.2 105.4 103.1 93.6 16.7 17.2 18.5 17.8 16.8 18.7 24.4 16.6 24.2 15.8 15.9 16.0 15.2 32.1 49.8 2.9 38.9 37.1 58.2 245.6 23.3 23.8 57.8 26.2 49.9 77.2 116.6 53.3 8.4 55.9 74.5 140.3 39.2 91.7 10.5 30.5 14.7 26.1 30.0 48.8 7.4 239.1 113.0 21.4 36.2 56.5 40.6 41.2 27.1 674.6 65.0 8.4 10.3 96.8 93.6 30.2 36.0 11.8 13.4 31.9 37.4 4.7 34.8 19.3 101.0 5.0 5.1 156.7 137.3 14.7 54.4 46.4 171.9 99.7 34.8 23.3 13.1 12.5 23.6 8.7 22.7 47.6 45.5 37.5 57.1 128.7 149.1 71.1 ECT2 ARHGEF31 ENSG00000114346 "Epithelial cell transforming 2" Q9H8V3 3 172750682-172821474 "Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Neurogenesis, Protein transport, Transport" "Guanine-nucleotide releasing factor" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 64.6;Spermatocytes: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA036363, HPA053261" Enhanced Nucleoplasm,Cytosol No Yes "Cluster 1: Neutrophils - Mixed function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA036363: AB_2732472, HPA053261: AB_2682094" "unprognostic (3.83e-2)" "unprognostic (4.34e-1)" "unprognostic (1.27e-2)" "unprognostic (4.22e-3)" "unprognostic (4.49e-2)" "unprognostic (5.02e-3)" "prognostic unfavorable (6.82e-6)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.82e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (2.24e-5)" "unprognostic (2.44e-2)" "prognostic unfavorable (1.19e-5)" "unprognostic (1.08e-2)" "unprognostic (1.46e-1)" "unprognostic (1.29e-1)" "unprognostic (1.33e-1)" 3.6 3.3 2.1 8.2 1.9 19.8 7.5 3.4 3.4 8.1 1.4 11.5 9.3 4.4 1.8 8.9 3.3 5.3 3.2 2.4 1.4 4.3 2.6 5.2 10.5 2.1 1.7 1.3 2.9 3.6 1.2 8.8 2.7 3.2 15.8 12.5 5.6 2.6 2.1 7.1 7.6 7.5 0.7 4.3 9.4 15.9 2.3 23.3 3.9 2.7 11.4 6.9 4.2 3.5 192.0 133.6 103.2 54.0 10.6 21.8 51.6 81.5 67.5 121.4 116.9 74.7 196.9 47.2 122.1 48.8 116.0 81.8 84.2 53.1 164.3 67.8 46.6 29.6 70.0 38.5 4.6 46.2 32.8 7.1 9.0 72.2 73.2 34.0 53.0 68.6 31.3 67.2 97.2 67.6 47.5 34.6 84.4 156.7 72.0 33.7 101.1 60.7 92.2 43.7 68.6 44.1 104.5 117.4 42.2 51.5 195.4 34.1 46.5 58.5 55.7 79.6 174.9 32.8 47.2 88.2 51.6 39.7 78.0 6.0 2.0 0.7 1.0 1.7 1.1 1.4 1.4 0.9 1.6 1.3 0.6 0.9 6.3 0.7 0.7 1.6 2.5 0.7 2.1 1.9 3.4 3.4 2.4 1.4 2.1 1.7 2.7 0.7 2.3 3.5 6.7 6.4 3.2 4.2 3.8 19.5 4.9 6.2 9.1 3.4 10.1 6.5 3.6 5.7 5.7 3.7 64.6 12.0 2.9 10.7 0.0 9.5 3.3 20.1 6.6 7.7 4.8 25.2 6.5 9.2 14.9 6.0 17.9 20.5 0.0 17.9 5.3 2.9 7.3 0.0 2.5 13.5 10.2 4.7 6.3 2.8 0.9 5.1 7.2 15.0 2.8 3.1 2.1 3.0 4.9 20.7 3.8 1.5 9.6 12.8 1.5 3.7 11.0 16.3 0.0 2.9 5.2 42.6 30.4 16.9 12.8 3.8 4.1 3.3 13.5 8.8 EDN1 ET1 ENSG00000078401 "Endothelin 1" P05305 6 12290361-12297194 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 44.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 749.7;Ductal cells: 316.3;Glandular and luminal cells: 289.7;Pancreatic endocrine cells: 268.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "non-classical monocyte: 4.9" "Lineage enriched" "Detected in single" 6 "monocytes: 4.9" "Cell line enhanced" "Detected in many" "EFO-21: 660.4;HUVEC TERT2: 446.8;T-47d: 137.5;TIME: 334.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA031976, CAB032500, CAB037291" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Secreted to blood" NA Yes 9740 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoli, Golgi apparatus" Nucleoplasm "CAB032500: AB_2096241, CAB037291: AB_259277, HPA031976: AB_10602489" "unprognostic (1.51e-2)" "unprognostic (2.38e-1)" "unprognostic (3.95e-2)" "unprognostic (9.72e-2)" "unprognostic (3.40e-1)" "unprognostic (1.91e-1)" "unprognostic (6.24e-2)" "unprognostic (2.94e-3)" "unprognostic (1.42e-1)" "unprognostic (8.92e-2)" "unprognostic (4.19e-2)" "unprognostic (3.17e-1)" "unprognostic (8.02e-3)" "unprognostic (2.09e-1)" "unprognostic (1.71e-1)" "unprognostic (1.34e-1)" "unprognostic (3.47e-1)" 44.6 1.8 14.7 7.3 13.8 4.7 23.6 13.6 18.2 6.2 9.7 10.6 10.4 7.0 6.3 12.1 9.4 13.5 7.8 12.6 12.2 7.7 3.1 36.6 5.6 15.1 13.6 2.6 9.6 1.4 1.1 18.5 15.2 5.5 14.5 1.0 12.1 8.9 7.6 11.8 9.8 11.3 13.1 12.3 10.4 4.7 15.7 1.7 3.4 6.4 2.4 9.9 5.9 14.2 10.3 57.6 1.1 0.1 0.3 0.2 0.2 18.2 16.0 15.0 12.4 74.6 8.6 0.0 660.4 7.2 9.2 5.4 0.0 10.6 11.0 0.8 0.0 0.0 2.1 2.3 0.8 0.0 0.0 0.4 6.2 3.0 2.1 4.7 446.8 0.0 0.0 0.0 56.8 1.6 0.2 0.3 0.6 10.4 0.7 0.2 5.1 0.1 35.3 9.4 0.6 0.0 1.8 53.1 0.1 117.2 137.5 0.8 334.3 37.1 30.1 0.7 23.5 0.3 0.4 1.3 0.3 0.0 1.6 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 4.9 0.1 0.0 0.0 14.7 13.8 13.6 18.2 12.6 12.2 15.1 13.6 15.2 13.1 15.7 14.2 190.7 173.1 23.8 2.9 0.8 189.9 749.7 99.9 151.4 0.2 68.7 26.8 2.2 8.6 110.6 38.6 0.0 1.8 0.8 189.7 3.9 316.3 13.3 187.2 16.3 236.8 15.6 2.7 3.6 218.9 0.4 9.0 22.4 289.7 1.3 0.8 169.2 1.8 1.8 1.7 3.0 43.8 12.2 5.0 6.7 19.8 5.6 5.3 8.8 6.5 10.9 0.3 0.0 3.5 0.6 268.5 145.7 0.4 0.4 185.8 119.6 8.3 27.4 0.4 6.6 1.8 21.8 1.0 0.6 53.7 64.5 0.8 9.7 0.1 196.6 141.8 EED "HEED, WAIT-1" ENSG00000074266 "Embryonic ectoderm development" O75530 11 86244753-86278813 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012211, HPA060089, HPA061140" Supported Supported Nucleoplasm NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 21: OE19 - Mitochondria" "Cluster 59: Non-specific - Transcription" Nucleoplasm "CAB012211: AB_2262066, HPA060089: AB_2684201, HPA061140: AB_2684437" "unprognostic (7.46e-2)" "unprognostic (4.40e-2)" "unprognostic (1.65e-1)" "unprognostic (1.02e-2)" "unprognostic (1.33e-1)" "unprognostic (3.13e-2)" "prognostic unfavorable (1.80e-5)" "unprognostic (2.90e-1)" "unprognostic (1.32e-2)" "unprognostic (2.39e-1)" "unprognostic (2.31e-1)" "unprognostic (9.19e-3)" "prognostic unfavorable (1.36e-7)" "unprognostic (1.67e-1)" "unprognostic (1.71e-1)" "unprognostic (1.33e-2)" "prognostic favorable (2.27e-5)" 9.3 9.0 13.2 16.3 13.1 9.2 11.4 15.0 15.8 13.8 13.1 12.1 12.1 11.5 15.2 12.7 10.6 9.3 8.9 12.8 13.5 11.5 11.9 8.5 28.8 12.9 12.8 12.1 10.5 9.1 9.4 14.5 13.1 11.7 11.9 16.4 10.3 10.6 10.5 12.1 11.6 10.2 12.9 14.4 10.9 10.3 13.6 17.8 10.7 11.1 32.1 13.0 12.1 13.9 34.2 37.8 40.9 16.8 22.6 20.2 47.0 49.2 22.6 46.3 46.8 121.0 64.4 79.8 50.6 15.8 44.2 41.4 48.7 26.8 43.2 79.7 22.7 51.4 38.7 36.3 19.8 54.2 33.4 12.4 18.0 46.8 20.1 17.5 20.9 34.7 58.8 16.2 39.0 55.2 51.5 55.4 30.4 107.8 18.4 56.2 49.1 38.8 29.1 55.4 27.5 22.4 63.5 29.6 14.5 29.1 49.2 22.6 19.0 48.1 44.1 70.0 43.2 9.2 32.1 63.9 13.7 46.6 36.8 31.0 9.1 15.0 25.4 15.3 22.1 45.0 33.2 32.0 13.9 47.3 26.4 29.6 3.9 19.3 16.8 9.2 58.6 19.1 13.2 13.1 15.0 15.8 12.8 13.5 12.9 12.8 13.1 12.9 13.6 13.9 15.4 6.4 9.3 28.1 32.7 25.6 11.6 27.5 25.0 26.4 13.3 11.8 9.5 11.5 15.4 7.3 18.8 45.2 31.0 16.1 19.6 14.5 7.7 17.6 17.1 16.6 7.2 15.8 35.0 10.2 36.8 14.8 16.3 15.5 15.9 15.0 13.2 11.4 16.9 32.0 45.6 12.8 12.2 14.5 32.5 3.6 22.7 15.2 19.6 37.5 30.4 11.5 25.7 31.2 38.9 11.9 11.1 17.3 17.6 11.9 11.7 8.6 21.3 18.3 6.6 14.3 24.5 18.7 20.0 16.9 16.8 24.9 31.6 17.5 15.0 20.9 EFNA1 "ECKLG, EPLG1, GMAN, LERK1, TNFAIP4" ENSG00000169242 "Ephrin A1" P20827 1 155127876-155134899 "Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 472.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 942.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "naive CD4 T-cell: 11.4;naive CD8 T-cell: 5.9" "Lineage enriched" "Detected in single" 23 "T-cells: 11.4" "Cell line enhanced" "Detected in many" "BEWO: 266.5;HaCaT: 95.5;SiHa: 156.9;SK-BR-3: 227.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069549 Approved "Secreted to blood" NA Yes 2800000 "Cluster 32: T-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA069549: " "unprognostic (5.14e-2)" "unprognostic (3.04e-3)" "unprognostic (5.03e-2)" "unprognostic (2.01e-1)" "unprognostic (1.59e-1)" "unprognostic (2.47e-2)" "unprognostic (1.78e-2)" "unprognostic (5.80e-3)" "unprognostic (1.53e-1)" "unprognostic (4.56e-2)" "unprognostic (2.00e-2)" "unprognostic (2.23e-1)" "unprognostic (4.44e-2)" "unprognostic (3.58e-1)" "unprognostic (1.93e-1)" "unprognostic (2.41e-1)" "unprognostic (1.32e-1)" 43.2 24.0 25.6 4.9 30.0 1.3 64.7 27.2 33.9 31.7 21.8 42.5 57.9 23.7 28.5 54.7 23.2 24.5 47.1 25.5 25.9 73.8 472.8 86.7 8.1 31.0 29.0 17.5 53.6 29.7 19.5 109.9 29.8 79.5 51.6 7.8 66.6 22.1 18.5 123.1 69.3 13.4 27.8 8.6 40.7 4.1 27.6 21.0 79.9 38.6 12.5 36.9 55.5 35.2 15.1 5.9 0.9 11.5 2.1 0.1 266.5 0.0 0.5 0.2 0.3 13.9 32.0 0.0 26.3 0.0 9.0 95.5 6.6 35.3 0.2 9.8 2.2 0.1 19.0 76.1 0.9 0.2 1.5 4.9 84.5 0.0 30.2 7.3 53.6 0.9 2.8 0.3 0.0 52.2 0.3 1.1 1.7 52.3 17.7 6.1 1.5 9.3 66.4 22.4 9.8 14.2 156.9 227.1 6.0 48.8 51.1 0.0 6.7 0.1 9.1 0.6 1.5 2.3 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 1.0 0.7 0.0 0.3 11.4 5.9 0.4 0.4 0.0 0.0 0.0 1.6 25.6 30.0 27.2 33.9 25.5 25.9 31.0 29.0 29.8 27.8 27.6 35.2 116.8 198.7 113.1 0.7 2.3 127.7 103.7 91.6 327.8 3.0 198.3 151.9 47.8 95.8 101.2 18.4 0.0 195.6 4.4 265.0 13.7 130.1 0.3 100.4 19.1 148.9 18.6 4.0 0.7 63.9 942.6 23.2 124.9 163.5 6.3 0.1 106.4 133.2 28.2 5.0 0.8 114.1 101.7 4.3 19.5 0.7 4.7 4.2 62.2 2.8 0.6 5.7 0.0 3.5 28.7 73.9 205.5 0.4 4.1 197.8 238.6 34.5 54.5 1.1 0.0 6.5 35.9 0.8 2.6 253.2 217.8 254.2 7.5 1.3 95.9 135.9 EFNA5 "AF1, EPLG7, LERK7" ENSG00000184349 "Ephrin A5" P52803 5 107376894-107670937 "Cancer-related genes, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 13 "Astrocytes: 291.2;Excitatory neurons: 798.5;Inhibitory neurons: 373.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 35.2;RPTEC TERT1: 50.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013282, HPA054047" Approved Approved Vesicles,Cytosol NA Yes 10000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Cytosol" "CAB013282: AB_2533353, HPA054047: AB_2682355" "unprognostic (1.67e-1)" "unprognostic (4.04e-2)" "unprognostic (7.52e-2)" "unprognostic (2.15e-3)" "unprognostic (3.98e-3)" "unprognostic (2.74e-2)" "unprognostic (8.91e-4)" "unprognostic (9.46e-3)" "unprognostic (4.92e-1)" "unprognostic (2.28e-3)" "unprognostic (1.26e-3)" "unprognostic (1.47e-1)" "prognostic unfavorable (1.92e-7)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.52e-1)" "unprognostic (2.13e-2)" "unprognostic (1.27e-1)" 4.1 1.1 4.5 2.0 6.5 0.1 4.0 1.3 13.6 10.1 0.0 2.3 0.8 1.1 2.0 7.1 2.9 2.7 6.8 3.1 10.2 3.4 0.3 2.4 0.8 0.9 0.3 4.0 0.5 2.5 2.7 2.4 0.6 4.3 2.3 2.5 5.6 4.7 0.5 9.7 0.8 2.2 0.0 5.3 2.5 1.4 2.1 1.4 1.0 1.4 2.5 3.5 4.8 5.4 12.7 22.2 35.2 0.0 16.7 14.2 3.6 0.3 6.3 4.5 11.6 0.2 13.9 0.0 20.5 2.4 7.1 13.1 19.4 18.0 3.6 0.0 12.9 0.1 11.9 0.0 3.1 0.6 0.0 16.0 15.4 0.0 14.4 3.9 13.8 0.0 0.0 0.0 8.3 12.0 0.0 0.0 4.6 0.1 1.9 0.0 16.9 0.4 50.9 15.5 5.8 14.7 6.0 8.9 3.8 11.2 3.9 2.2 0.2 28.3 5.0 17.4 7.1 1.2 0.0 8.3 12.4 0.8 31.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.4 0.1 0.7 0.0 0.0 0.0 0.1 4.5 6.5 1.3 13.6 3.1 10.2 0.9 0.3 0.6 0.0 2.1 5.4 1.1 9.6 24.4 291.2 0.0 15.9 22.5 18.5 6.2 4.3 11.8 8.5 30.6 11.5 26.0 14.7 0.0 20.3 3.3 4.3 23.5 1.7 1.8 3.2 14.8 8.2 12.0 0.0 798.5 1.3 3.3 16.9 5.6 6.3 0.0 0.1 9.7 0.0 1.7 6.7 373.1 8.5 18.3 0.3 7.0 3.7 18.3 0.4 8.8 37.5 3.6 4.7 2.1 26.2 8.7 13.9 4.9 21.8 1.7 14.1 0.0 0.1 19.6 1.4 0.0 1.3 3.7 0.1 4.0 14.9 24.2 3.8 2.2 2.3 5.9 23.1 EID1 "C15orf3, CRI1, EID-1" ENSG00000255302 "EP300 interacting inhibitor of differentiation 1" Q9Y6B2 15 48878134-48880173 "Predicted intracellular proteins" "Cell cycle, Differentiation, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA051122, HPA051123" Approved Supported Nucleoplasm NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 38: Heart - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA051122: AB_2681350, HPA051123: AB_2681351" "unprognostic (1.38e-1)" "unprognostic (6.69e-2)" "unprognostic (1.64e-1)" "unprognostic (3.18e-2)" "unprognostic (7.81e-2)" "prognostic unfavorable (9.99e-4)" "unprognostic (1.10e-1)" "unprognostic (2.79e-2)" "unprognostic (1.39e-1)" "unprognostic (1.41e-1)" "unprognostic (6.75e-3)" "unprognostic (2.46e-1)" "unprognostic (3.62e-3)" "prognostic unfavorable (2.91e-4)" "unprognostic (2.04e-2)" "unprognostic (2.13e-1)" "unprognostic (2.09e-1)" 128.6 206.3 96.9 95.4 103.7 61.0 112.0 98.7 153.6 149.8 107.2 143.9 81.6 161.0 132.1 96.6 134.9 120.9 280.1 103.9 111.3 147.9 125.1 99.5 112.0 102.6 101.7 186.7 102.0 144.8 130.1 93.3 100.5 156.1 71.3 158.4 98.3 147.3 278.8 57.6 79.0 141.8 102.1 115.3 84.2 67.9 104.5 117.2 138.5 227.6 83.9 113.1 81.4 123.2 131.5 109.1 260.9 231.6 239.9 316.9 16.4 337.6 304.5 220.3 294.3 95.0 58.0 174.9 305.3 207.0 155.5 115.4 130.2 130.8 247.9 484.1 127.1 300.6 235.8 4.1 186.0 183.0 132.2 278.1 115.1 146.1 91.9 221.4 262.8 151.2 182.3 162.6 258.5 188.7 134.6 174.1 0.5 98.9 97.4 185.1 302.6 290.6 287.4 142.3 233.8 234.6 210.2 80.2 401.2 212.7 145.0 240.6 262.9 322.4 177.7 305.6 299.3 208.4 616.7 125.1 264.6 410.0 230.0 345.0 311.5 275.5 221.3 285.3 209.2 168.3 249.4 231.8 358.1 183.2 179.6 165.3 40.4 230.0 297.5 354.9 332.4 440.1 96.9 103.7 98.7 153.6 103.9 111.3 102.6 101.7 100.5 102.1 104.5 123.2 327.4 387.8 207.7 31.3 127.5 175.5 139.9 459.5 138.9 345.3 188.5 286.4 480.8 183.0 329.9 261.1 120.9 351.6 168.0 46.0 606.5 386.5 17.5 116.0 324.4 356.8 233.7 219.2 38.0 268.0 151.2 443.4 88.2 116.7 188.0 173.8 339.8 166.2 211.3 238.9 43.5 114.0 301.1 208.1 262.0 49.2 702.4 189.7 487.4 30.9 302.2 844.1 213.1 28.6 80.9 191.0 102.1 651.4 134.3 81.4 91.9 446.5 240.2 329.9 322.1 350.7 379.1 98.6 75.0 125.9 145.6 109.6 180.7 463.2 101.5 96.9 EIF5B "DKFZp434I036, FLJ10524, IF2, KIAA0741" ENSG00000158417 "Eukaryotic translation initiation factor 5B" O60841 2 99337371-99401326 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Hydrolase, Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 769.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034648, HPA040095" Approved Approved "Plasma membrane,Cytosol" NA Yes 210000 "Cluster 6: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Plasma membrane" "HPA034648: AB_10601902, HPA040095: AB_2676843" "unprognostic (1.23e-1)" "unprognostic (6.94e-2)" "unprognostic (2.01e-1)" "unprognostic (5.03e-2)" "unprognostic (4.65e-2)" "unprognostic (5.88e-3)" "prognostic unfavorable (7.15e-10)" "unprognostic (6.80e-2)" "unprognostic (9.84e-3)" "prognostic favorable (8.99e-4)" "unprognostic (1.68e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (1.42e-6)" "unprognostic (6.89e-2)" "unprognostic (3.24e-2)" "unprognostic (1.43e-1)" "unprognostic (7.93e-3)" 39.4 31.6 50.3 32.8 53.5 20.8 33.9 50.8 88.8 31.3 51.1 56.3 23.1 35.2 41.7 44.4 29.6 18.5 89.6 48.8 55.3 50.9 38.4 30.9 32.6 54.1 52.5 27.0 48.6 32.1 28.2 29.6 55.0 44.0 30.0 23.8 36.5 33.5 102.9 39.4 29.1 28.7 52.8 30.7 42.1 48.6 53.6 26.2 29.3 56.2 36.6 47.8 33.7 53.0 117.0 57.2 63.8 83.5 75.5 88.7 105.4 100.4 62.9 65.3 64.6 132.5 80.9 132.5 84.6 75.2 77.4 64.9 112.6 97.3 114.6 80.8 67.4 159.6 57.7 175.9 59.7 158.0 94.3 60.2 66.8 91.0 92.1 55.9 96.6 80.0 179.6 64.4 95.2 94.9 100.8 145.7 99.5 76.2 83.0 86.8 94.7 108.2 134.9 96.2 53.8 50.9 54.6 123.8 85.3 120.4 50.5 103.0 106.9 100.7 99.3 53.2 90.7 47.4 72.0 106.0 73.3 172.0 75.9 19.8 11.0 13.7 15.5 12.5 18.2 20.9 16.3 15.5 8.4 19.8 15.9 17.0 2.9 18.3 17.3 26.2 12.5 6.4 50.3 53.5 50.8 88.8 48.8 55.3 54.1 52.5 55.0 52.8 53.6 53.0 121.7 109.0 219.6 23.8 152.4 321.3 200.4 209.0 84.8 103.8 159.1 112.1 579.1 135.8 198.6 343.9 50.1 143.7 142.9 135.0 144.8 210.5 769.9 143.1 175.0 153.2 157.9 154.2 27.4 235.1 205.3 130.4 82.0 157.5 172.7 90.0 146.3 480.9 134.7 77.4 28.3 206.7 144.5 123.5 128.9 144.0 124.5 95.7 142.3 18.7 157.7 91.8 145.2 21.6 36.7 282.6 93.8 175.7 183.2 253.9 102.7 226.2 165.4 111.3 276.1 167.3 157.7 575.3 505.0 99.1 324.8 181.4 133.4 101.7 185.1 244.7 ELOVL1 Ssc1 ENSG00000066322 "ELOVL fatty acid elongase 1" Q9BW60 1 43363398-43368074 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033426, HPA056557" Enhanced Supported "Endoplasmic reticulum" NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Endoplasmic reticulum" "CAB033426: AB_2099896, HPA056557: AB_2683173" "unprognostic (5.23e-2)" "prognostic unfavorable (3.63e-5)" "unprognostic (8.00e-2)" "unprognostic (8.45e-2)" "unprognostic (7.60e-2)" "unprognostic (7.40e-2)" "prognostic unfavorable (2.79e-7)" "unprognostic (4.74e-2)" "unprognostic (1.33e-1)" "unprognostic (4.37e-1)" "prognostic unfavorable (8.51e-4)" "unprognostic (1.83e-1)" "unprognostic (2.88e-2)" "unprognostic (1.41e-2)" "unprognostic (1.28e-1)" "unprognostic (1.73e-1)" "unprognostic (9.00e-2)" 78.5 54.7 77.2 39.8 115.6 52.9 66.6 121.1 116.9 57.1 61.4 63.9 51.6 46.5 30.6 176.6 38.9 42.4 47.2 76.8 93.2 59.7 45.8 59.6 40.1 152.0 110.1 28.9 55.4 46.2 27.2 51.0 140.7 58.7 48.6 8.4 72.7 48.8 24.1 201.9 55.4 50.8 114.8 57.1 70.6 18.6 107.7 22.2 66.8 28.0 55.7 68.5 86.8 165.7 108.0 119.5 22.6 44.8 148.4 138.2 70.2 125.2 154.5 153.5 122.4 105.9 182.5 73.9 94.3 193.6 130.3 119.4 79.7 152.2 93.2 94.6 53.9 96.6 77.3 77.1 128.2 84.2 98.0 106.2 168.2 180.9 198.4 114.8 155.0 27.7 68.1 54.8 178.5 79.5 19.9 69.5 33.5 136.9 120.2 43.6 59.9 89.7 195.5 128.7 27.4 28.8 73.7 258.4 105.8 66.8 121.2 82.4 132.2 129.7 82.5 161.2 161.3 26.6 31.2 35.4 127.8 85.2 120.1 134.9 189.6 172.7 105.1 180.0 93.4 109.0 98.4 103.2 212.8 94.2 63.5 88.0 133.0 114.7 179.6 148.8 113.8 203.1 77.2 115.6 121.1 116.9 76.8 93.2 152.0 110.1 140.7 114.8 107.7 165.7 44.0 19.2 12.5 7.5 28.1 15.6 25.9 61.1 29.6 5.7 60.3 37.5 4.7 34.3 40.2 40.5 10.4 93.4 36.0 114.0 7.9 91.5 3.4 22.9 26.3 43.6 19.2 67.8 3.8 100.1 127.4 26.1 48.4 45.2 21.0 52.6 24.7 16.7 74.9 3.3 3.4 33.8 46.8 46.3 37.5 4.6 20.2 41.5 12.4 7.5 92.5 13.7 32.0 3.0 66.1 133.3 63.9 25.6 19.0 44.7 66.0 23.3 14.5 9.5 19.7 10.0 39.7 8.4 11.2 70.1 31.0 95.9 31.5 50.8 47.2 49.2 EMP2 XMP ENSG00000213853 "Epithelial membrane protein 2" P54851 16 10528422-10580632 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 230.6" "Group enriched" "Detected in many" 7 "Alveolar cells type 1: 4163.5;Suprabasal keratinocytes: 1174.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "MCF7: 268.1;RT4: 182.0;SK-BR-3: 256.2;T-47d: 156.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014711, HPA070816" Approved Approved Nucleoplasm,Cytosol No Yes "Cluster 42: Non-specific - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm Cytosol "HPA014711: AB_1848147, HPA070816: " "unprognostic (1.75e-1)" "unprognostic (4.05e-2)" "unprognostic (3.45e-3)" "unprognostic (4.82e-1)" "prognostic unfavorable (2.23e-4)" "unprognostic (9.27e-2)" "unprognostic (8.90e-2)" "unprognostic (2.41e-2)" "unprognostic (4.40e-1)" "unprognostic (1.86e-1)" "unprognostic (6.24e-2)" "unprognostic (3.19e-1)" "prognostic unfavorable (2.85e-8)" "unprognostic (9.54e-2)" "unprognostic (2.73e-1)" "unprognostic (2.54e-2)" "unprognostic (9.52e-2)" 56.8 9.7 15.5 12.4 15.5 0.7 49.5 14.8 17.1 51.0 18.6 48.0 15.5 25.9 45.5 152.1 35.5 17.7 64.1 13.6 15.6 20.3 83.2 230.6 5.7 16.1 16.8 54.9 13.7 32.8 13.3 23.0 16.0 38.8 34.1 2.0 39.2 17.3 22.5 140.6 28.3 22.3 15.2 16.0 39.1 7.2 18.8 5.3 27.7 25.4 32.8 39.6 72.9 15.7 28.7 39.1 15.9 18.9 35.0 30.0 31.3 40.0 36.8 23.9 35.7 128.5 98.2 0.2 12.6 48.4 17.2 123.9 41.1 49.8 31.3 0.1 26.1 0.1 76.6 72.1 6.1 0.2 0.4 18.4 13.1 31.9 3.2 5.4 10.1 0.1 9.6 2.6 66.9 268.1 0.4 0.6 18.3 46.4 9.5 7.5 18.2 61.7 5.5 182.0 22.0 25.0 49.6 256.2 15.2 45.2 156.6 6.2 5.7 75.5 32.2 25.6 22.7 0.8 1.0 0.2 33.2 0.5 75.7 1.3 0.2 0.3 0.2 0.2 0.2 0.2 0.2 0.1 0.1 0.3 0.2 0.2 1.1 0.3 0.3 0.3 0.2 0.1 15.5 15.5 14.8 17.1 13.6 15.6 16.1 16.8 16.0 15.2 18.8 15.7 239.7 4163.5 368.4 13.1 3.1 356.9 137.9 172.2 111.0 2.3 105.0 94.0 53.1 100.1 255.8 42.3 0.0 74.2 3.1 119.5 0.0 3.8 8.0 78.8 30.9 183.9 104.9 0.0 0.7 67.0 17.8 152.7 46.4 51.9 36.7 68.7 161.0 235.1 10.1 0.0 0.6 207.8 81.4 19.6 136.5 9.3 190.7 17.0 87.2 41.2 33.6 5.7 0.0 22.6 0.6 32.9 158.4 276.1 1.6 86.0 21.0 0.2 142.8 2.2 52.6 256.3 129.3 5.7 12.9 319.5 1174.3 48.0 9.3 73.3 178.5 221.4 EPHA2 ECK ENSG00000142627 "EPH receptor A2" P29317 1 16124337-16156069 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cataract, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 147.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 202.3;Glandular and luminal cells: 182.9;Squamous epithelial cells: 156.3;Suprabasal keratinocytes: 248.3;Urothelial cells: 200.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 94 "plasmacytoid DC: 9.4" "Lineage enriched" "Detected in single" 94 "dendritic cells: 9.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 201.1;PC-3: 229.0;U-251 MG: 242.1;WM-115: 258.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB010464 Supported "Nuclear speckles,Golgi apparatus,Plasma membrane,Cell Junctions" NA Yes 12000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cell Junctions" "Nuclear speckles, Golgi apparatus" "CAB010464: AB_631436" "unprognostic (9.41e-2)" "unprognostic (1.67e-1)" "unprognostic (4.13e-2)" "unprognostic (1.67e-2)" "unprognostic (6.22e-2)" "unprognostic (9.12e-2)" "unprognostic (5.24e-2)" "unprognostic (1.29e-3)" "unprognostic (2.52e-2)" "unprognostic (7.05e-3)" "unprognostic (1.52e-3)" "unprognostic (2.77e-1)" "unprognostic (2.65e-2)" "unprognostic (2.08e-1)" "unprognostic (1.73e-1)" "unprognostic (4.77e-3)" "unprognostic (4.40e-2)" 21.4 9.5 3.5 4.8 3.1 0.3 14.6 2.9 3.7 38.2 11.7 12.4 10.0 12.1 1.3 147.9 13.5 28.2 15.8 3.1 3.1 18.7 18.9 17.9 7.6 3.8 3.7 5.8 23.2 3.7 7.4 14.0 3.8 11.2 5.8 6.4 67.7 4.2 4.6 40.3 12.8 3.7 3.6 7.6 15.6 1.8 4.3 3.2 15.2 5.1 11.1 56.1 58.8 3.1 76.9 151.7 41.4 20.1 2.9 3.5 24.3 45.2 63.4 79.9 50.6 63.9 201.1 0.1 189.8 25.9 98.8 30.6 9.9 104.4 27.6 0.4 7.0 0.0 46.7 41.1 51.3 0.1 0.2 4.8 38.1 43.7 95.6 125.0 86.4 0.0 0.3 0.1 51.6 24.3 0.0 0.0 20.0 57.2 229.0 0.1 37.6 0.2 85.1 39.0 0.1 6.4 87.8 21.2 6.1 21.3 3.0 0.9 108.1 28.5 76.7 2.0 242.1 0.0 0.5 0.6 22.0 0.1 258.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 3.5 3.1 2.9 3.7 3.1 3.1 3.8 3.7 3.8 3.6 4.3 3.1 17.1 54.5 38.4 2.0 1.2 202.3 114.3 110.9 66.0 2.7 39.5 43.9 6.5 44.3 113.4 9.2 4.2 9.7 8.9 96.8 0.0 33.8 5.8 104.5 19.2 26.3 3.0 0.0 0.1 14.2 1.2 5.8 68.3 182.9 5.7 0.4 29.3 23.3 1.9 0.0 0.2 42.0 34.6 1.6 17.0 0.2 3.4 3.7 26.6 4.7 1.1 7.1 0.0 0.0 0.0 104.6 111.7 0.0 0.0 60.8 22.4 1.8 89.8 2.5 32.9 11.6 21.2 0.2 0.8 156.3 248.3 7.5 2.6 0.4 42.9 200.4 EPOR ENSG00000187266 "Erythropoietin receptor" P19235 19 11377207-11384342 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes, Congenital erythrocytosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 114.7;Hepatic stellate cells: 66.8;Hofbauer cells: 42.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 20.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA077654 Supported "Nuclear speckles,Plasma membrane" "Intracellular and membrane" NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane" "Nuclear speckles" "HPA077654: " "unprognostic (9.13e-2)" "unprognostic (7.14e-2)" "unprognostic (1.45e-2)" "unprognostic (1.04e-1)" "unprognostic (1.88e-1)" "unprognostic (1.11e-1)" "unprognostic (3.70e-1)" "unprognostic (1.50e-2)" "unprognostic (5.60e-2)" "unprognostic (9.00e-2)" "prognostic favorable (3.17e-5)" "unprognostic (6.37e-3)" "unprognostic (1.59e-2)" "unprognostic (2.08e-1)" "unprognostic (2.00e-1)" "unprognostic (7.48e-2)" "unprognostic (1.01e-3)" 6.5 17.5 6.0 1.4 6.3 22.4 5.0 6.7 8.2 7.1 7.7 2.7 1.4 3.3 13.6 1.3 6.7 2.3 9.7 6.3 6.0 21.6 10.7 6.4 2.2 6.1 6.1 3.1 11.8 23.2 8.2 8.0 6.4 4.6 1.7 3.3 3.3 7.3 2.3 1.6 2.3 1.8 6.0 11.9 7.8 1.8 6.2 1.7 30.2 1.5 1.6 3.1 3.7 6.3 3.7 1.2 3.6 4.2 5.3 3.4 2.1 2.2 7.0 3.6 4.5 1.3 1.4 2.5 4.0 4.1 5.0 0.9 2.8 1.4 4.1 2.1 1.6 14.3 1.3 2.1 3.8 2.9 5.5 2.4 0.5 4.8 3.3 8.5 8.5 5.3 12.5 12.0 4.1 3.3 2.7 3.5 1.9 2.0 9.6 7.2 6.3 5.6 3.4 1.9 1.4 11.0 1.5 2.0 6.4 3.7 3.6 4.9 3.5 1.9 2.6 6.6 2.1 6.0 4.7 2.8 10.5 2.9 2.1 9.3 3.7 3.0 1.7 4.6 3.6 2.0 3.4 2.5 2.1 1.2 3.7 2.2 10.2 0.8 7.3 0.1 3.3 2.4 6.0 6.3 6.7 8.2 6.3 6.0 6.1 6.1 6.4 6.0 6.2 6.3 6.1 19.2 18.8 24.8 11.5 2.3 4.0 2.0 2.8 3.8 3.6 6.1 6.5 5.7 3.1 20.2 0.0 2.2 5.2 1.3 3.9 2.2 0.8 9.9 6.8 13.5 8.4 114.7 2.2 3.3 12.2 9.8 15.3 13.9 26.6 1.2 66.8 3.5 42.4 1.7 3.0 3.5 2.0 17.0 4.0 0.6 2.8 15.4 8.8 7.5 4.6 7.9 11.3 1.0 1.6 3.1 0.4 4.1 3.8 1.8 0.2 1.0 2.9 2.5 19.7 3.8 18.5 5.1 7.7 1.6 1.0 3.0 9.6 2.6 1.8 1.2 ERCC6L "FLJ20105, PICH, RAD26L" ENSG00000186871 "ERCC excision repair 6 like, spindle assembly checkpoint helicase" Q2NKX8 X 72204657-72239027 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.2;lymphoid tissue: 3.6" "Cell type enhanced" "Detected in some" "Erythroid cells: 3.4;Granulosa cells: 2.5;Spermatocytes: 2.1;Spermatogonia: 2.4;Squamous epithelial cells: 2.4" "Cancer enhanced" "Detected in many" "testis cancer: 11.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 4 "NK-cell: 1.7" "Lineage enriched" "Detected in single" 4 "NK-cells: 1.7" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA050492 Approved Uncertain Nucleoplasm,Centrosome,Cytosol No Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "Nucleoplasm, Cytosol" "HPA050492: AB_2681145" "prognostic unfavorable (1.80e-4)" "unprognostic (2.93e-1)" "unprognostic (1.95e-2)" "unprognostic (5.76e-3)" "unprognostic (2.43e-1)" "unprognostic (2.36e-1)" "unprognostic (9.23e-6)" "unprognostic (8.63e-3)" "unprognostic (1.57e-2)" "unprognostic (1.99e-2)" "unprognostic (3.68e-5)" "unprognostic (4.61e-2)" "unprognostic (0.00e+0)" "unprognostic (2.97e-3)" "unprognostic (9.56e-2)" "unprognostic (1.17e-1)" "unprognostic (6.41e-2)" 0.1 0.1 0.1 1.3 0.2 3.2 0.4 0.8 0.2 0.4 0.1 0.9 0.7 0.2 0.2 1.1 0.2 0.2 0.1 0.1 0.0 0.1 0.1 0.1 2.3 0.1 0.0 0.3 0.1 0.0 0.1 0.5 0.1 0.1 1.1 0.5 0.3 0.0 0.1 0.6 0.6 0.3 0.0 0.5 0.7 0.8 0.2 3.6 0.1 0.0 2.7 0.2 0.4 0.6 19.0 16.3 14.6 9.3 1.0 1.7 8.0 19.8 9.1 17.0 17.7 13.3 11.6 30.5 7.3 7.2 23.0 15.2 27.8 14.8 30.1 17.5 20.2 10.5 5.5 7.9 0.0 20.7 14.2 0.2 0.9 23.7 4.4 2.8 9.6 15.1 14.1 7.3 17.6 14.8 19.8 12.1 26.6 18.3 24.8 16.4 26.2 5.4 4.4 11.5 12.0 8.6 14.7 9.8 3.6 11.8 7.5 4.6 6.0 11.4 18.3 21.8 13.1 5.7 9.4 25.9 8.1 14.1 11.7 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.4 0.1 1.7 0.1 0.1 0.4 0.1 0.1 0.2 0.8 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.6 0.1 0.0 0.0 0.0 0.9 0.3 0.2 0.5 0.0 0.0 0.3 0.6 0.5 1.5 0.2 0.0 0.0 1.1 0.9 0.6 0.0 0.0 0.3 0.9 0.8 0.3 0.0 3.4 0.9 0.0 1.7 0.5 0.0 0.5 0.0 2.5 0.0 0.0 1.0 0.0 0.7 0.4 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 1.7 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.4 2.1 2.4 2.4 0.1 0.4 0.3 0.2 0.9 0.1 ERH DROER ENSG00000100632 "ERH mRNA splicing and mitosis factor" P84090 14 69380128-69398299 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002567 Approved Approved Nucleoplasm,Cytosol NA Yes 190000 "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "HPA002567: AB_1078749" "unprognostic (2.42e-2)" "unprognostic (1.69e-1)" "unprognostic (3.42e-1)" "unprognostic (4.78e-2)" "unprognostic (9.34e-2)" "unprognostic (8.61e-3)" "prognostic unfavorable (7.89e-5)" "unprognostic (1.93e-1)" "unprognostic (1.06e-1)" "unprognostic (8.83e-3)" "unprognostic (2.31e-1)" "unprognostic (9.24e-2)" "unprognostic (2.49e-1)" "unprognostic (1.12e-1)" "unprognostic (9.32e-2)" "unprognostic (4.31e-2)" "unprognostic (2.39e-1)" 107.7 113.7 143.3 119.0 146.2 144.4 119.3 145.1 186.7 97.0 146.9 110.5 110.0 111.9 150.3 75.5 112.8 70.1 100.2 145.4 159.1 118.3 142.5 76.3 147.1 142.8 146.8 107.0 66.7 128.2 58.3 98.1 147.6 87.0 122.9 116.7 110.0 84.3 107.0 58.1 99.1 114.8 153.7 96.5 88.7 91.1 149.6 212.2 97.6 85.8 168.4 117.0 51.2 154.5 972.7 574.9 704.6 409.1 271.8 201.1 356.9 450.7 261.3 401.3 372.0 598.5 403.1 879.9 224.3 305.3 340.3 296.1 563.4 376.9 484.2 437.9 428.3 441.4 366.1 731.8 419.6 389.3 334.6 227.1 203.0 355.9 317.2 239.2 337.8 584.5 454.0 301.6 335.7 1043.2 714.1 750.8 537.2 525.6 686.0 558.9 599.9 320.6 415.4 672.8 449.1 439.8 442.1 464.6 355.6 330.8 539.9 564.4 351.4 425.7 699.7 286.7 480.0 351.7 336.2 1096.1 345.1 417.5 442.4 76.6 101.4 80.9 76.6 98.9 77.5 122.2 100.0 88.0 107.4 94.3 92.7 88.2 45.3 121.5 95.1 122.8 116.5 147.0 143.3 146.2 145.1 186.7 145.4 159.1 142.8 146.8 147.6 153.7 149.6 154.5 231.2 60.9 54.3 22.2 189.1 273.1 225.0 702.7 180.4 126.4 244.2 314.2 118.9 181.6 282.2 253.8 37.5 455.3 179.4 117.5 673.1 363.8 100.4 238.1 198.9 211.9 188.5 252.6 23.9 275.3 560.3 237.0 120.3 158.7 127.6 186.7 169.6 239.9 341.5 74.0 23.1 244.0 510.6 147.5 215.2 51.3 270.9 162.5 307.7 16.9 302.3 350.3 174.0 19.6 34.6 289.8 183.9 259.2 237.9 288.9 203.9 508.5 278.4 119.8 190.7 177.7 273.8 321.5 230.9 251.0 318.8 279.9 165.3 281.4 265.9 230.6 ERN1 "IRE1, IRE1P" ENSG00000178607 "Endoplasmic reticulum to nucleus signaling 1" O75460 17 64039080-64130819 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Transcription, Transcription regulation, Unfolded protein response" "Hydrolase, Kinase, Multifunctional enzyme, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 53.0;pancreas: 66.7" "Cell type enhanced" "Detected in many" "Plasma cells: 325.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 17.9" "Group enriched" "Detected in many" 5 "dendritic cells: 7.7;granulocytes: 17.9;T-cells: 9.0" "Cell line enhanced" "Detected in many" "Karpas-707: 74.6;RPMI-8226: 40.2;U-266/70: 77.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009495, HPA027730" Supported NA Yes "Cluster 38: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB009495: AB_2098712, HPA027730: AB_10602494" "unprognostic (2.52e-1)" "unprognostic (1.16e-2)" "unprognostic (1.89e-1)" "unprognostic (4.05e-3)" "unprognostic (3.63e-2)" "unprognostic (2.81e-2)" "unprognostic (9.14e-2)" "unprognostic (2.72e-2)" "unprognostic (4.55e-1)" "unprognostic (6.17e-2)" "unprognostic (2.95e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.68e-4)" "unprognostic (4.65e-1)" "unprognostic (1.89e-1)" "unprognostic (1.36e-2)" "unprognostic (3.11e-2)" 9.5 53.0 1.5 5.4 1.7 13.4 7.5 2.6 3.2 22.6 2.1 7.7 6.3 10.1 6.4 9.5 14.3 6.2 6.1 1.6 2.4 5.6 23.5 16.5 5.8 1.7 1.0 16.9 66.7 4.3 19.5 5.6 1.3 9.9 4.5 8.8 15.7 7.1 6.8 11.3 10.6 5.6 1.0 15.8 16.2 2.8 1.6 6.8 10.2 2.4 6.6 8.3 11.7 1.7 4.0 4.0 2.2 4.8 4.8 4.4 9.8 4.1 9.7 2.8 1.3 2.5 2.3 6.6 3.2 2.8 3.5 3.6 1.9 4.5 6.1 1.6 1.5 6.0 3.2 2.4 19.6 3.2 2.1 3.8 8.1 6.4 21.5 3.5 5.0 4.7 4.2 74.6 2.8 3.9 4.5 1.0 0.6 3.6 3.2 4.2 4.2 40.2 1.1 5.5 7.1 3.5 4.3 6.1 5.7 3.5 3.8 5.9 5.9 2.5 4.1 6.4 2.7 77.4 23.9 4.8 4.0 2.1 4.2 17.9 0.9 0.4 4.9 0.4 9.0 0.2 3.3 4.1 0.4 0.3 0.9 0.9 4.9 2.5 0.3 7.7 0.8 1.0 1.5 1.7 2.6 3.2 1.6 2.4 1.7 1.0 1.3 1.0 1.6 1.7 31.9 0.0 36.1 7.2 27.8 22.0 54.3 8.3 15.4 4.0 35.0 29.7 8.6 11.5 8.6 12.9 6.2 8.1 106.4 10.0 1.9 12.6 2.3 26.1 49.1 18.3 79.7 11.2 8.6 27.3 8.8 42.2 52.0 79.4 8.2 11.8 13.9 26.8 8.0 3.3 6.1 8.2 8.2 15.7 71.3 1.7 4.7 60.4 74.7 12.2 10.2 3.5 28.8 6.0 4.6 17.9 7.3 6.0 325.8 44.7 7.9 4.4 6.1 26.5 0.0 19.0 25.7 4.0 4.1 27.7 45.0 54.9 88.2 12.0 9.6 60.1 ESCO2 "EFO2, RBS" ENSG00000171320 "Establishment of sister chromatid cohesion N-acetyltransferase 2" Q56NI9 8 27771949-27812640 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;intestine: 11.0;lymphoid tissue: 8.5;testis: 5.7" "Group enriched" "Detected in many" 4 "Erythroid cells: 44.6;Spermatocytes: 62.0;Spermatogonia: 80.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.3" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA027243, HPA053679" Supported "Nucleoplasm,Golgi apparatus,Cell Junctions" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Golgi apparatus" "Cell Junctions" "HPA027243: AB_2672175, HPA053679: AB_2682227" "unprognostic (7.86e-2)" "unprognostic (1.50e-2)" "prognostic favorable (1.04e-4)" "unprognostic (5.13e-3)" "unprognostic (9.50e-2)" "unprognostic (8.67e-3)" "unprognostic (7.30e-4)" "unprognostic (5.24e-3)" "unprognostic (2.24e-2)" "unprognostic (2.54e-2)" "unprognostic (7.51e-4)" "unprognostic (2.23e-1)" "unprognostic (1.65e-14)" "unprognostic (6.65e-3)" "unprognostic (5.32e-1)" "unprognostic (5.85e-2)" "unprognostic (4.06e-1)" 0.5 0.4 0.0 2.7 0.2 6.0 1.2 0.4 0.2 0.5 0.0 3.7 11.0 0.6 0.0 2.4 0.2 0.6 0.2 0.0 0.0 0.1 0.7 0.4 4.6 0.0 0.0 0.1 1.0 0.3 0.0 1.1 0.1 0.3 4.3 0.5 0.3 0.1 0.0 1.1 7.9 0.7 0.0 0.8 2.5 5.7 0.0 8.5 0.3 0.2 5.7 0.8 0.5 0.2 54.6 39.9 17.9 22.0 2.3 3.9 10.2 31.6 12.9 27.8 32.5 14.2 10.7 21.0 16.6 8.3 24.7 29.2 22.0 8.5 43.6 15.8 9.2 24.4 16.2 15.3 0.3 12.5 21.4 0.7 0.9 17.0 4.2 3.0 11.6 15.2 20.0 30.0 17.7 10.5 49.8 5.9 12.2 29.9 13.4 21.7 53.0 14.8 9.6 31.9 8.0 11.7 15.5 19.6 7.9 6.5 13.2 14.1 5.2 17.9 37.0 36.2 25.7 4.0 11.1 25.2 10.2 20.5 25.2 0.0 0.2 0.1 0.0 0.4 0.0 0.4 0.2 0.2 0.6 0.0 0.1 0.1 0.2 0.3 0.1 0.0 1.3 0.3 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 4.7 0.0 2.4 2.3 0.6 2.1 1.8 1.2 1.5 1.7 1.2 0.0 3.3 0.0 4.2 4.6 1.3 8.2 0.0 0.4 5.4 1.3 2.6 1.0 1.2 44.6 0.3 0.0 6.6 3.2 5.6 3.1 1.3 11.4 1.4 1.5 5.4 0.0 0.4 4.4 2.0 2.5 3.5 0.8 1.8 3.2 0.0 1.0 0.5 0.1 4.1 1.0 0.9 0.1 1.5 0.0 11.5 0.6 15.1 0.1 1.6 2.0 6.6 0.8 2.3 62.0 80.0 6.8 0.6 1.0 3.1 1.8 8.0 1.4 ESPL1 "ESP1, KIAA0165, SEPA" ENSG00000135476 "Extra spindle pole bodies like 1, separase" Q14674 12 53268299-53293638 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Chromosome partition" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.5;esophagus: 15.4;lymphoid tissue: 10.7" "Cell type enhanced" "Detected in many" "Ionocytes: 22.4;Proximal enterocytes: 22.6;Squamous epithelial cells: 7.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "CAB012185, HPA073188" Approved Supported Nucleoplasm,Vesicles NA Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 45: Enterocytes - Digestion" Nucleoplasm Vesicles "CAB012185: AB_304056, HPA073188: " "unprognostic (1.57e-1)" "unprognostic (3.56e-2)" "unprognostic (3.84e-2)" "prognostic unfavorable (5.32e-5)" "unprognostic (2.91e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (2.01e-5)" "prognostic unfavorable (7.14e-4)" "unprognostic (1.59e-2)" "unprognostic (2.48e-1)" "unprognostic (4.17e-3)" "unprognostic (1.18e-2)" "unprognostic (7.42e-13)" "prognostic favorable (7.10e-4)" "unprognostic (2.39e-1)" "unprognostic (7.41e-2)" "unprognostic (1.42e-1)" 0.4 0.2 0.0 2.4 0.0 8.5 0.5 0.0 0.0 3.5 0.0 1.5 3.9 0.2 0.0 15.4 0.2 0.4 0.1 0.0 0.0 0.9 0.6 0.4 4.4 0.0 0.0 0.1 0.1 0.0 0.0 1.1 0.0 0.1 1.4 0.0 2.0 0.1 0.0 2.6 4.3 0.7 0.0 1.0 0.9 6.2 0.1 10.7 0.1 0.0 4.9 0.6 5.9 0.0 27.8 23.6 27.6 21.1 0.6 1.9 17.5 15.9 8.6 28.8 19.2 15.8 22.7 49.9 9.5 6.8 17.4 20.2 32.6 9.9 14.3 13.7 32.8 30.6 24.1 11.1 0.1 19.5 25.2 0.6 0.6 15.5 7.6 2.8 15.4 22.2 42.6 41.0 9.1 29.2 30.6 16.4 22.5 14.5 12.9 29.3 30.2 21.4 4.2 11.6 18.9 15.8 11.9 20.4 10.1 13.0 36.9 12.7 8.2 14.5 27.2 11.9 25.5 32.5 29.7 31.9 8.2 19.0 27.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.3 0.6 0.9 0.3 0.5 0.6 0.0 1.0 1.3 0.9 0.0 0.4 3.7 0.0 1.9 0.6 2.7 0.0 0.2 0.8 0.2 0.8 1.0 3.5 1.3 0.7 0.0 2.3 1.1 3.6 0.7 0.0 4.4 0.7 6.8 2.6 0.0 0.4 2.7 22.4 0.6 2.1 1.2 0.0 1.3 0.0 1.0 0.0 0.0 0.0 0.0 0.5 1.5 1.3 0.4 2.1 0.4 22.6 6.6 0.2 0.0 0.0 0.4 0.9 5.5 4.1 7.4 0.6 0.3 0.4 0.1 2.8 0.4 EVA1A "FAM176A, FLJ13391, TMEM166" ENSG00000115363 "Eva-1 homolog A, regulator of programmed cell death" Q9H8M9 2 75469302-75569722 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "liver: 191.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 41.7;Cytotrophoblasts: 43.3;Hepatocytes: 78.1;Proximal tubular cells: 77.3;Syncytiotrophoblasts: 124.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 85.7;U-138 MG: 110.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008055 Approved Supported "Vesicles,Plasma membrane" NA Yes "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "Plasma membrane" "HPA008055: AB_1080308" "unprognostic (2.72e-1)" "unprognostic (2.61e-2)" "unprognostic (4.14e-3)" "unprognostic (1.01e-1)" "unprognostic (1.36e-2)" "unprognostic (3.60e-2)" "unprognostic (5.02e-2)" "unprognostic (1.77e-2)" "unprognostic (1.77e-1)" "prognostic favorable (5.67e-4)" "unprognostic (7.33e-2)" "unprognostic (1.22e-1)" "prognostic favorable (5.80e-4)" "unprognostic (8.19e-2)" "unprognostic (4.37e-2)" "unprognostic (2.43e-2)" "unprognostic (9.07e-2)" 1.1 0.5 0.2 1.1 0.9 0.1 3.4 0.6 0.5 9.8 0.2 0.7 1.7 2.8 9.6 0.4 3.7 1.2 1.6 0.2 0.3 20.0 191.6 20.7 0.4 1.1 0.5 0.5 23.8 7.6 1.1 17.3 0.9 0.9 0.7 0.5 8.9 2.2 1.2 2.7 1.8 2.0 0.7 10.8 0.6 2.9 0.8 5.1 1.8 1.6 0.3 0.8 0.8 0.8 1.0 14.5 1.5 0.4 3.1 21.2 1.4 68.0 45.3 59.2 30.1 0.5 1.2 0.1 6.3 85.7 54.2 9.4 1.7 14.4 36.8 0.0 1.1 0.0 2.5 45.7 2.2 0.0 0.1 15.0 8.3 73.2 33.3 59.0 37.2 0.0 0.0 0.0 46.1 0.0 0.1 0.0 3.3 0.2 23.5 7.9 0.1 0.0 32.5 0.5 0.9 1.6 6.2 0.4 53.7 2.2 0.2 0.3 31.0 110.3 46.3 2.0 71.9 0.7 0.1 0.3 62.5 0.0 59.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.6 0.5 0.2 0.3 1.1 0.5 0.9 0.7 0.8 0.8 6.1 41.7 35.4 1.0 0.9 2.8 13.7 14.3 3.4 1.2 11.7 12.3 0.3 1.5 23.0 11.0 0.0 43.3 0.4 0.1 27.4 30.5 12.2 13.3 1.4 4.8 1.8 0.0 1.1 16.1 25.9 4.7 0.0 11.4 0.0 0.0 2.2 78.1 3.5 0.0 0.9 1.1 4.1 0.8 1.2 9.4 0.3 0.6 28.4 2.8 0.1 0.0 0.0 1.5 0.9 9.7 0.0 0.7 0.0 12.3 0.5 77.3 1.7 0.1 0.0 2.2 9.0 2.2 0.9 1.1 0.9 124.8 1.1 0.0 1.6 10.5 EXO1 "HEX1, hExoI" ENSG00000174371 "Exonuclease 1" Q9UQ84 1 241847967-241895148 "Predicted intracellular proteins" "DNA damage, DNA excision, DNA repair, Immunity, Meiosis" "DNA-binding, Endonuclease, Excision nuclease, Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 17.3;lymphoid tissue: 11.1" "Cell type enhanced" "Detected in some" "Early spermatids: 9.3;Erythroid cells: 7.4;Extravillous trophoblasts: 16.7;Plasma cells: 11.8;Spermatocytes: 9.3;Spermatogonia: 9.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA053079, HPA069738" Enhanced "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA053079: AB_2682037, HPA069738: AB_2732140" "unprognostic (6.33e-3)" "unprognostic (8.54e-3)" "unprognostic (9.47e-3)" "prognostic unfavorable (8.21e-4)" "unprognostic (2.43e-1)" "unprognostic (6.34e-2)" "prognostic unfavorable (6.94e-7)" "unprognostic (1.84e-3)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.40e-2)" "unprognostic (4.81e-3)" "unprognostic (9.40e-2)" "unprognostic (0.00e+0)" "unprognostic (6.72e-2)" "unprognostic (2.29e-1)" "unprognostic (1.75e-1)" "unprognostic (3.57e-1)" 0.5 0.3 0.2 3.3 0.2 17.3 1.2 0.1 0.7 0.5 0.1 3.2 2.9 0.8 0.0 2.5 0.3 0.4 0.2 0.3 0.1 0.3 0.5 0.6 5.8 0.1 0.2 0.2 0.3 0.7 0.1 3.3 0.2 0.2 3.7 0.0 0.5 0.2 0.1 1.8 2.5 1.2 0.2 1.5 1.6 5.7 0.3 11.1 0.4 0.0 6.4 1.2 0.8 0.4 41.3 26.8 43.4 28.6 2.7 6.7 36.5 53.4 17.7 46.7 50.5 33.9 22.5 44.3 25.3 12.6 25.1 40.0 55.5 22.5 54.8 69.5 48.4 41.5 28.8 17.3 1.0 59.8 29.4 1.7 1.1 46.8 12.5 5.7 14.7 43.4 84.6 57.0 37.8 19.0 65.9 33.6 60.4 49.7 26.0 46.2 40.5 47.5 9.6 25.6 48.1 60.9 34.8 27.9 19.5 20.2 25.8 36.6 5.5 44.9 39.5 42.7 72.9 41.5 59.0 71.3 15.6 48.1 54.9 0.8 0.2 0.0 0.2 0.0 0.0 0.3 0.2 0.2 0.1 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.9 0.3 0.2 0.2 0.1 0.7 0.3 0.1 0.1 0.2 0.2 0.2 0.3 0.4 0.2 0.0 0.0 0.3 0.7 0.8 0.1 0.7 0.0 0.0 0.3 0.5 2.3 0.0 0.1 0.0 0.0 5.3 0.2 1.2 0.0 0.1 9.3 0.3 0.4 0.7 0.0 7.4 1.0 0.0 16.7 0.9 1.1 0.5 0.0 4.6 0.4 0.0 3.3 0.0 2.9 0.5 0.0 0.3 0.8 2.1 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.1 0.0 0.0 11.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 9.3 9.8 2.7 0.1 4.0 0.8 0.8 1.9 0.3 EXT1 "LGCR, LGS, ttv" ENSG00000182197 "Exostosin glycosyltransferase 1" Q16394 8 117794490-118111826 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease variant, Hereditary multiple exostoses, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 229.6;Inhibitory neurons: 421.4;Microglial cells: 144.3;Oligodendrocyte precursor cells: 162.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 95.5;fHDF/TERT166: 82.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044394 Uncertain NA Yes 17000000 "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA044394: AB_10963838" "unprognostic (1.29e-2)" "prognostic unfavorable (7.04e-4)" "unprognostic (2.73e-2)" "unprognostic (2.02e-3)" "unprognostic (2.19e-1)" "unprognostic (7.55e-2)" "unprognostic (1.99e-1)" "prognostic unfavorable (1.20e-5)" "unprognostic (1.70e-1)" "unprognostic (3.01e-2)" "unprognostic (1.31e-2)" "unprognostic (6.58e-2)" "unprognostic (1.27e-2)" "unprognostic (9.84e-2)" "unprognostic (9.49e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (1.85e-1)" 5.1 4.2 2.0 5.2 2.5 1.1 4.3 2.3 2.3 7.6 3.9 7.7 14.1 4.9 2.9 5.5 3.8 5.8 7.0 3.4 1.3 3.8 13.3 7.9 3.0 1.1 2.1 5.0 5.5 3.3 1.8 11.1 1.0 5.0 8.2 2.7 3.2 7.7 1.5 7.8 11.7 6.1 1.4 5.1 5.3 2.4 1.2 3.0 5.2 2.4 3.8 11.8 4.2 1.9 29.3 8.5 13.5 5.5 22.8 23.0 5.9 51.5 95.5 40.9 39.4 10.0 3.1 0.5 24.8 82.1 24.0 19.8 5.0 31.4 55.7 12.5 9.9 1.5 5.9 6.5 10.0 0.0 1.6 10.8 10.8 38.8 38.5 47.7 28.1 2.9 0.9 7.4 18.7 3.2 1.8 0.2 4.6 13.7 10.1 0.0 4.1 1.3 23.1 7.6 4.5 4.0 8.0 3.9 9.2 32.6 5.3 0.5 32.0 35.2 28.7 32.0 15.8 5.5 5.1 2.4 36.5 0.0 9.2 0.1 0.4 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.4 0.2 0.3 0.1 2.0 2.5 2.3 2.3 3.4 1.3 1.1 2.1 1.0 1.4 1.2 1.9 21.1 19.2 6.0 127.3 3.0 54.8 23.0 27.7 10.2 23.6 7.8 10.8 6.5 24.3 13.7 7.3 14.6 6.5 5.1 49.2 0.0 37.3 1.8 17.7 37.1 25.9 4.8 1.7 229.6 20.1 3.9 32.6 11.7 18.2 7.0 108.3 16.8 32.9 2.5 10.1 421.4 25.5 4.1 37.9 13.9 2.7 17.4 9.6 19.6 144.3 8.1 5.9 4.1 162.8 101.8 27.4 16.1 36.1 5.3 19.3 44.9 4.9 14.2 22.4 0.0 17.1 36.4 0.6 5.1 12.6 47.3 12.2 4.2 35.0 26.3 26.8 F2RL1 "GPR11, PAR2" ENSG00000164251 "F2R like trypsin receptor 1" P55085 5 76818933-76835315 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 59.4;stomach 1: 44.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 109.9;Distal enterocytes: 124.7;Gastric mucus-secreting cells: 74.5;Glandular and luminal cells: 74.7;Paneth cells: 86.1;Suprabasal keratinocytes: 168.4;Urothelial cells: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 42.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 42.0" "Cell line enhanced" "Detected in many" "PC-3: 126.0;RPTEC TERT1: 205.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB012989, HPA014091" Approved Approved "Plasma membrane" NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB012989: AB_2533199, HPA014091: AB_2668939" "unprognostic (1.29e-2)" "unprognostic (4.05e-2)" "prognostic favorable (3.88e-4)" "unprognostic (1.98e-2)" "unprognostic (8.22e-2)" "prognostic unfavorable (5.88e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (8.92e-4)" "unprognostic (6.13e-2)" "unprognostic (4.07e-1)" "unprognostic (2.16e-3)" "unprognostic (1.52e-2)" "prognostic favorable (5.86e-7)" "unprognostic (1.11e-1)" "unprognostic (1.74e-1)" "unprognostic (3.76e-2)" "unprognostic (9.73e-2)" 1.0 1.3 0.8 6.2 0.9 1.7 8.0 0.5 0.8 3.6 8.9 59.4 45.8 2.9 4.8 8.2 8.2 29.9 4.6 0.5 0.8 31.8 7.1 4.1 1.4 1.7 2.2 0.5 23.6 5.2 1.5 3.9 1.4 5.0 53.0 2.6 8.9 11.5 0.3 37.5 41.0 2.7 1.0 3.8 44.0 0.6 0.9 1.1 8.3 0.2 1.6 27.5 5.8 0.8 32.7 52.1 4.3 0.2 1.5 4.0 33.1 1.6 17.1 0.9 2.7 45.0 81.8 0.0 69.5 3.7 78.1 54.4 27.1 24.0 1.5 0.1 26.8 0.8 1.0 32.8 10.6 0.0 0.3 5.5 67.3 8.0 49.8 8.0 84.9 7.8 0.4 0.0 0.1 17.6 3.8 0.1 5.7 17.9 126.0 0.1 0.0 0.8 205.9 58.5 2.1 0.4 12.3 12.6 0.3 48.5 5.3 0.3 57.1 0.1 31.8 0.1 0.3 4.8 1.0 0.1 18.7 0.0 1.4 11.9 10.0 1.8 0.4 3.2 2.1 0.5 3.8 1.9 4.7 0.1 3.4 2.1 42.0 0.7 0.5 0.5 1.0 4.0 0.8 0.9 0.5 0.8 0.5 0.8 1.7 2.2 1.4 1.0 0.9 0.8 0.3 9.6 3.7 0.0 0.9 109.9 17.8 4.5 10.8 0.5 10.5 6.3 0.3 32.9 12.7 31.3 0.0 5.4 0.2 124.7 1.9 28.0 0.0 40.9 5.1 1.2 13.1 2.5 0.2 15.0 7.9 2.9 74.5 74.7 2.5 1.0 1.1 9.6 0.9 0.0 1.4 50.8 4.1 1.9 3.8 0.0 0.0 2.1 1.8 1.0 2.6 0.0 0.0 0.0 0.0 44.7 86.1 0.0 0.1 34.1 62.9 19.3 25.0 2.0 0.0 0.4 2.8 0.9 1.3 37.0 168.4 2.1 2.1 0.1 50.7 116.0 FAM110A "bA371L19.3, C20orf55" ENSG00000125898 "Family with sequence similarity 110 member A" Q9BQ89 20 833715-857463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 71.2" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 71.7;Extravillous trophoblasts: 138.2;Langerhans cells: 74.2;Macrophages: 70.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "basophil: 543.5;eosinophil: 163.4;intermediate monocyte: 160.6;non-classical monocyte: 248.6" "Group enriched" "Detected in all" 9 "granulocytes: 543.5;monocytes: 248.6" "Cell line enhanced" "Detected in all" "SK-BR-3: 84.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB034110, HPA069240" Uncertain Uncertain Nucleoplasm,Vesicles,Cytosol Yes Yes "Cluster 10: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Vesicles" Cytosol "CAB034110: AB_1562838, HPA069240: AB_2686103" "unprognostic (6.33e-2)" "unprognostic (2.53e-2)" "unprognostic (1.57e-2)" "unprognostic (3.43e-2)" "unprognostic (1.81e-1)" "unprognostic (3.37e-2)" "unprognostic (4.90e-3)" "unprognostic (5.55e-2)" "unprognostic (6.01e-2)" "unprognostic (4.78e-2)" "unprognostic (2.35e-2)" "unprognostic (2.47e-1)" "prognostic unfavorable (4.42e-4)" "unprognostic (9.64e-3)" "unprognostic (1.17e-2)" "unprognostic (6.42e-3)" "unprognostic (4.21e-3)" 4.2 5.5 4.2 5.9 5.2 8.8 9.0 3.1 3.6 10.1 3.9 5.5 10.0 2.5 4.7 39.3 2.5 2.3 4.0 2.8 3.4 8.8 3.6 12.3 6.7 5.5 5.3 2.8 5.5 11.0 7.9 6.6 5.6 19.3 3.2 1.2 18.4 3.6 4.0 71.2 9.7 1.1 3.3 23.4 6.1 3.7 6.6 6.9 7.6 0.6 7.8 9.2 18.4 3.6 27.7 7.3 4.1 7.6 4.4 1.9 27.8 8.5 4.7 5.3 4.7 16.0 16.9 8.9 3.7 5.3 7.6 43.7 3.3 22.2 4.4 7.3 2.3 18.6 4.9 4.2 2.0 5.1 6.3 1.2 27.1 7.3 7.1 1.6 3.6 8.1 10.2 21.5 4.9 16.4 14.3 13.8 5.3 17.7 12.3 14.1 7.0 11.7 4.1 19.6 7.7 9.1 7.4 84.0 3.8 1.7 34.9 7.5 4.8 12.6 9.1 11.5 9.6 7.8 7.3 3.8 2.0 13.2 9.2 543.5 28.3 163.4 13.2 160.6 11.7 7.0 23.7 27.2 36.2 11.7 28.1 27.9 15.3 6.9 248.6 3.9 43.0 24.2 4.2 5.2 3.1 3.6 2.8 3.4 5.5 5.3 5.6 3.3 6.6 3.6 3.5 0.0 7.0 0.0 18.5 32.6 17.0 31.6 71.7 0.3 26.7 20.1 2.9 7.2 15.7 11.0 0.0 41.5 24.3 5.1 1.9 10.1 9.9 3.0 1.7 8.0 10.8 16.2 0.5 6.0 138.2 3.6 5.1 5.2 51.5 1.4 17.2 0.7 20.0 5.0 0.4 8.8 16.2 36.7 74.2 24.3 3.4 70.0 7.2 1.9 29.9 0.3 25.7 0.5 0.1 13.4 7.8 1.9 3.5 20.9 16.1 2.4 7.4 2.6 6.6 1.1 4.3 3.4 4.9 57.7 36.8 31.3 26.1 14.2 10.4 24.6 FAM111A "FLJ22794, KIAA1895" ENSG00000166801 "Family with sequence similarity 111 member A" Q96PZ2 11 59142748-59155039 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Host-virus interaction" "DNA-binding, Hydrolase, Protease" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 83.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039529, HPA040176" Approved Approved "Nucleoplasm,Nucleoli fibrillar center" NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nucleoli fibrillar center" "HPA039529: AB_10795149, HPA040176: AB_10793958" "unprognostic (4.12e-3)" "unprognostic (8.47e-2)" "unprognostic (7.80e-3)" "unprognostic (1.00e-1)" "unprognostic (1.81e-1)" "unprognostic (2.41e-1)" "unprognostic (5.83e-3)" "unprognostic (1.81e-1)" "unprognostic (9.88e-2)" "unprognostic (5.96e-2)" "unprognostic (2.74e-2)" "unprognostic (3.53e-2)" "prognostic unfavorable (1.15e-5)" "unprognostic (2.66e-2)" "unprognostic (1.79e-1)" "unprognostic (1.76e-2)" "prognostic favorable (4.39e-4)" 14.8 18.9 7.0 23.1 7.0 20.3 16.0 6.7 9.6 20.8 12.9 17.1 22.5 13.8 17.3 12.8 16.5 18.7 11.6 6.6 7.6 23.7 17.9 25.2 36.1 9.0 7.7 14.6 15.0 16.9 14.3 19.5 8.1 33.2 19.3 9.1 19.0 10.7 5.5 18.8 27.6 10.9 7.8 42.5 22.5 7.1 8.2 42.3 26.6 4.1 30.1 14.8 17.4 8.4 66.0 16.2 7.9 7.5 16.9 21.4 5.1 91.6 50.8 38.5 56.3 24.9 59.0 94.3 37.1 29.7 51.2 21.9 26.9 40.4 47.4 86.0 1.2 36.3 22.7 7.6 17.8 58.7 45.7 14.5 9.6 36.2 11.1 22.0 37.7 57.2 4.8 76.7 42.2 18.0 85.6 36.9 3.5 19.5 17.5 59.9 28.7 22.8 25.4 57.6 0.2 2.3 48.6 38.5 17.5 4.1 80.1 24.7 37.0 61.9 55.5 42.5 42.7 39.0 43.4 15.3 34.3 39.5 75.9 6.0 5.0 4.8 4.2 3.4 5.3 2.6 2.7 3.2 4.6 2.6 2.4 2.5 5.4 5.0 1.9 1.2 3.1 2.2 7.0 7.0 6.7 9.6 6.6 7.6 9.0 7.7 8.1 7.8 8.2 8.4 38.9 64.1 43.7 14.4 27.4 8.5 10.7 21.3 26.2 1.7 24.2 24.3 5.5 14.3 24.7 16.5 0.0 11.1 40.5 20.8 9.8 13.8 0.2 31.5 26.0 25.9 6.0 42.5 0.2 7.7 1.4 22.7 30.5 20.7 27.8 83.9 30.0 8.1 28.2 0.0 0.2 24.8 22.4 31.3 19.5 1.8 13.1 39.2 7.2 21.5 40.2 25.2 47.4 12.1 3.9 7.5 17.6 6.8 29.7 14.2 19.4 10.3 36.9 7.3 0.0 17.0 14.3 0.4 2.1 24.3 8.8 4.4 41.3 48.8 18.6 14.0 FAM111B CANP ENSG00000189057 "Family with sequence similarity 111 member B" Q6SJ93 11 59107185-59127412 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 18.0" "Cell type enhanced" "Detected in many" "B-cells: 12.8;Erythroid cells: 9.1;Plasma cells: 8.8;Squamous epithelial cells: 7.1;Undifferentiated cells: 10.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory B-cell: 3.3;naive B-cell: 2.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA038637 Uncertain Approved Nucleoplasm,Cytosol No Yes "Cluster 37: B-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm Cytosol "HPA038637: AB_10672522" "unprognostic (2.31e-1)" "unprognostic (2.68e-2)" "unprognostic (1.80e-3)" "unprognostic (6.94e-2)" "unprognostic (1.89e-1)" "unprognostic (1.96e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (1.49e-3)" "unprognostic (1.40e-2)" "unprognostic (4.85e-2)" "prognostic unfavorable (1.17e-5)" "unprognostic (1.01e-2)" "unprognostic (1.24e-5)" "unprognostic (2.94e-2)" "unprognostic (1.80e-1)" "unprognostic (1.20e-3)" "unprognostic (1.24e-1)" 0.9 0.5 0.5 5.9 0.6 4.8 2.7 2.8 1.8 1.0 0.1 5.6 3.4 1.0 0.5 3.4 0.5 0.8 0.3 0.6 1.1 0.4 2.5 1.1 12.3 0.5 1.0 0.2 0.6 0.9 0.0 1.7 0.7 1.0 5.8 1.3 0.8 0.4 0.4 4.4 4.0 2.0 0.1 1.8 3.2 0.8 0.6 18.0 0.9 0.1 13.3 1.7 1.0 2.1 72.6 18.5 26.6 0.4 2.7 4.9 0.3 53.5 26.7 31.2 46.1 38.7 28.0 89.8 35.4 15.7 26.3 54.7 39.5 36.2 55.2 46.8 9.5 9.8 32.3 16.9 0.1 0.3 11.1 1.2 1.2 30.3 2.4 6.0 16.9 24.1 2.8 81.9 37.2 27.3 57.7 0.6 0.3 43.2 21.0 60.1 39.7 34.7 16.8 61.2 5.2 16.9 44.4 50.8 8.7 9.7 56.2 5.0 9.4 24.1 52.4 73.5 49.6 62.6 48.4 0.6 35.0 0.4 35.4 0.2 0.1 0.1 0.1 0.0 0.1 3.3 0.2 0.3 0.1 2.6 0.1 0.1 1.6 0.0 0.1 0.1 0.7 0.1 0.5 0.6 2.8 1.8 0.6 1.1 0.5 1.0 0.7 0.1 0.6 2.1 0.7 0.0 0.0 0.0 12.8 4.2 2.2 4.2 1.8 0.0 2.5 4.2 0.3 0.0 1.4 0.0 0.0 1.1 1.4 4.0 0.0 0.8 0.0 0.9 1.6 1.2 0.0 9.1 0.0 0.0 0.4 1.5 3.6 1.9 0.0 6.3 0.0 0.2 3.9 0.0 0.0 4.4 2.0 0.3 1.6 0.0 0.0 2.4 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.6 1.3 0.0 8.8 0.7 0.5 0.1 1.6 0.0 0.0 1.3 1.8 0.1 1.0 7.1 2.7 0.1 3.2 1.1 10.4 1.6 FAM161A "FLJ13305, RP28" ENSG00000170264 "FAM161 centrosomal protein A" Q3B820 2 61824848-61854143 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Sensory transduction, Vision" "Ciliopathy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 28.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 100.1;Early spermatids: 183.2;Late spermatids: 293.1;Rod photoreceptor cells: 417.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032119 Approved NA Yes "Cluster 49: Eosinophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA032119: AB_10602806" "unprognostic (1.14e-1)" "unprognostic (1.36e-1)" "unprognostic (4.23e-2)" "prognostic unfavorable (9.02e-4)" "unprognostic (1.73e-1)" "unprognostic (2.16e-1)" "unprognostic (1.56e-5)" "unprognostic (7.62e-2)" "unprognostic (1.72e-1)" "unprognostic (2.14e-2)" "unprognostic (4.35e-2)" "unprognostic (2.00e-2)" "unprognostic (1.66e-1)" "unprognostic (5.33e-2)" "unprognostic (3.93e-1)" "unprognostic (8.08e-3)" "unprognostic (7.04e-2)" 0.9 1.2 0.8 0.5 1.1 0.3 1.1 0.6 1.6 2.1 2.4 1.0 0.4 1.6 1.2 1.1 4.0 1.4 1.5 0.9 1.1 1.9 0.7 1.0 0.7 0.8 0.9 5.2 2.3 1.9 2.4 1.1 0.8 1.0 0.6 28.9 0.7 1.1 1.2 0.6 0.7 0.6 0.6 0.7 2.6 5.5 1.0 1.6 3.6 0.3 0.6 1.1 1.1 0.9 3.4 3.1 7.1 3.3 3.4 3.2 2.1 2.9 1.5 3.4 4.2 2.1 1.7 6.6 1.5 0.5 6.1 1.6 4.3 0.5 8.0 4.5 4.7 2.4 2.8 3.3 2.9 2.7 0.5 1.3 0.0 6.6 1.9 4.0 3.7 6.4 0.9 2.5 2.4 1.3 4.9 5.2 11.0 4.2 3.3 8.4 12.1 3.3 2.4 0.8 8.7 7.3 6.2 0.8 4.7 6.7 1.5 1.8 0.7 5.9 5.2 4.2 6.7 3.8 3.1 8.1 4.2 4.5 1.2 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.8 1.1 0.6 1.6 0.9 1.1 0.8 0.9 0.8 0.6 1.0 0.9 3.9 3.2 9.7 20.2 3.7 5.5 9.4 10.2 6.2 49.7 4.8 7.0 14.5 7.2 10.5 20.2 100.1 14.0 2.3 1.5 1.9 4.3 183.2 42.7 11.0 6.7 6.0 5.5 16.6 3.8 7.7 10.7 5.1 4.8 4.5 42.7 4.2 3.8 3.6 16.8 19.0 2.5 14.2 1.2 3.6 293.1 20.8 2.3 8.8 4.7 2.0 42.4 2.1 11.1 33.0 1.3 0.3 16.6 4.0 4.7 0.0 13.0 47.1 417.2 0.0 14.2 9.0 98.0 39.3 5.3 4.1 11.1 3.6 16.4 3.5 3.4 FAM72A "LMPIP, MGC57827, p17, RP11-312O7.1, UGENE" ENSG00000196550 "Family with sequence similarity 72 member A" Q5TYM5 1 206186179-206204414 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.9" "Cell type enhanced" "Detected in many" "Early spermatids: 29.5;Kupffer cells: 18.2;Late spermatids: 30.2;Spermatocytes: 28.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA043271, HPA067321" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA Yes "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "Plasma membrane, Cytosol" "HPA043271: AB_2678402, HPA067321: " "unprognostic (3.61e-2)" "unprognostic (1.58e-1)" "unprognostic (1.80e-1)" "unprognostic (5.20e-5)" "unprognostic (3.61e-1)" "unprognostic (1.19e-3)" "unprognostic (1.01e-5)" "unprognostic (7.70e-3)" "unprognostic (1.45e-2)" "unprognostic (5.58e-3)" "unprognostic (2.87e-2)" "unprognostic (1.03e-1)" "unprognostic (4.44e-16)" "unprognostic (1.82e-1)" "unprognostic (1.94e-2)" "unprognostic (4.83e-2)" "unprognostic (3.89e-1)" 4.0 3.1 2.6 5.9 2.9 8.4 3.6 9.1 3.1 1.3 1.0 2.2 3.1 0.9 0.4 2.5 1.8 2.7 1.2 3.1 4.0 1.3 2.0 2.6 10.9 5.4 4.4 1.1 1.4 1.6 0.8 3.5 5.8 1.1 2.3 0.2 1.0 0.7 0.6 5.9 2.9 2.0 4.1 6.3 1.5 7.1 4.8 8.6 0.9 1.0 7.5 1.5 1.5 4.7 21.1 16.4 17.7 7.7 2.6 3.1 21.1 14.6 6.3 17.1 12.7 9.9 31.1 54.2 12.3 3.8 18.8 24.7 20.9 8.1 20.2 29.5 16.3 24.3 16.4 13.9 1.8 42.9 27.0 4.4 1.4 15.1 26.7 5.1 10.7 45.7 50.1 36.7 10.7 12.9 26.9 38.3 32.1 15.1 22.1 29.5 30.6 41.4 9.8 3.2 17.7 10.2 10.6 9.7 9.3 20.1 20.5 23.2 5.5 13.5 15.5 17.7 24.9 29.1 44.8 48.4 11.1 34.9 18.8 0.0 5.9 0.0 0.7 8.0 0.2 1.7 1.4 1.4 4.6 0.5 0.1 0.3 1.0 0.6 4.8 1.9 2.9 2.1 2.6 2.9 9.1 3.1 3.1 4.0 5.4 4.4 5.8 4.1 4.8 4.7 5.9 0.0 1.5 0.0 2.4 1.8 0.4 1.2 1.2 0.3 0.8 0.6 1.5 0.0 0.9 0.0 0.0 0.8 3.7 4.9 0.0 1.0 29.5 1.5 1.5 8.4 0.0 0.4 0.1 0.8 3.8 1.8 0.5 0.7 0.0 0.3 7.1 0.4 9.4 0.0 0.2 3.6 0.0 18.2 5.8 30.2 0.0 6.9 3.6 0.0 9.6 0.6 2.1 0.0 0.1 0.6 0.0 0.0 1.6 0.4 1.3 0.3 2.1 0.2 0.0 0.9 2.2 28.0 4.1 2.0 1.0 0.7 1.4 0.8 1.6 0.8 FAM72B RP11-439A17.6 ENSG00000188610 "Family with sequence similarity 72 member B" Q86X60 1 121167646-121185539 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.2;lymphoid tissue: 10.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 7.3;Early spermatids: 11.3;Erythroid cells: 5.9;Hepatic stellate cells: 6.4;Spermatocytes: 17.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "HPA043271, HPA067321" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "Plasma membrane, Cytosol" "HPA043271: AB_2678402, HPA067321: " "unprognostic (8.53e-2)" "unprognostic (1.97e-2)" "unprognostic (1.63e-3)" "unprognostic (1.25e-3)" "unprognostic (4.36e-1)" "unprognostic (1.05e-1)" "unprognostic (1.26e-4)" "unprognostic (8.22e-5)" "unprognostic (1.30e-2)" "unprognostic (1.79e-2)" "unprognostic (1.36e-4)" "unprognostic (2.46e-2)" "unprognostic (0.00e+0)" "unprognostic (2.39e-2)" "unprognostic (1.71e-1)" "unprognostic (1.17e-2)" "unprognostic (5.30e-2)" 0.8 0.6 1.2 3.7 1.0 6.2 0.8 2.0 1.1 0.5 1.3 1.1 1.3 0.5 0.4 1.6 0.4 1.0 0.3 1.2 1.2 0.4 0.4 0.6 8.1 1.6 1.4 0.4 0.2 0.7 0.2 1.4 1.6 0.2 1.2 0.1 0.4 0.2 0.1 1.9 1.1 0.7 1.3 2.0 1.0 2.3 1.3 10.3 0.3 0.2 6.6 0.8 0.7 1.4 28.6 10.3 16.5 8.2 1.6 2.4 13.3 14.7 6.2 16.8 14.1 0.1 14.5 62.9 19.9 2.7 16.4 17.1 23.1 8.3 25.9 41.1 17.3 27.2 12.0 12.5 1.0 47.7 23.2 1.3 0.9 13.0 26.5 4.2 10.3 51.0 36.1 37.3 12.4 12.1 24.1 39.1 31.6 14.9 20.6 35.8 35.8 28.7 6.7 3.2 18.0 10.4 11.1 8.6 8.6 16.9 11.4 36.5 3.6 13.8 23.5 27.3 26.6 32.6 44.1 61.3 12.4 50.8 32.6 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.4 0.3 1.2 1.0 2.0 1.1 1.2 1.2 1.6 1.4 1.6 1.3 1.3 1.4 1.3 0.0 0.0 0.0 1.6 1.0 0.1 0.2 0.0 0.0 0.3 0.6 0.4 0.0 0.1 0.0 0.0 0.8 0.1 7.3 0.0 0.2 11.3 0.2 0.4 2.5 0.0 5.9 0.1 0.2 2.3 0.6 1.1 0.2 0.0 0.5 6.4 0.0 1.1 0.0 0.3 4.9 0.0 1.9 2.8 3.0 0.6 1.6 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.1 2.3 0.0 2.5 0.0 2.1 0.0 0.7 0.0 0.0 0.3 0.9 17.0 3.1 3.5 1.0 0.1 1.2 0.2 3.6 0.0 FAM72C RP5-998N21.9 ENSG00000263513 "Family with sequence similarity 72 member C" H0Y354 1 143955364-143971965 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.9;lymphoid tissue: 5.4" "Cell type enhanced" "Detected in some" "Erythroid cells: 7.8;Extravillous trophoblasts: 4.5;Sertoli cells: 6.6;Spermatocytes: 9.4;Spermatogonia: 3.5" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-266/84: 64.9" "HPA043271, HPA067321" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "Plasma membrane, Cytosol" "HPA043271: AB_2678402, HPA067321: " "unprognostic (2.18e-1)" "unprognostic (1.50e-1)" "unprognostic (6.45e-3)" "unprognostic (2.69e-2)" "unprognostic (2.21e-1)" "unprognostic (3.98e-3)" "unprognostic (9.46e-5)" "unprognostic (1.23e-3)" "unprognostic (4.36e-1)" "unprognostic (7.26e-2)" "unprognostic (1.04e-2)" "unprognostic (1.95e-1)" "unprognostic (0.00e+0)" "unprognostic (2.95e-1)" "unprognostic (4.70e-2)" "unprognostic (5.82e-2)" "unprognostic (1.47e-2)" 0.4 0.2 0.1 1.5 0.1 2.9 0.3 0.2 0.2 0.2 0.0 0.4 0.6 0.2 0.0 1.3 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.3 4.5 0.1 0.1 0.1 0.2 0.0 0.0 0.5 0.1 0.1 0.6 0.0 0.2 0.0 0.0 1.2 0.4 0.3 0.1 1.2 0.3 1.6 0.1 5.4 0.1 0.1 4.5 0.4 0.4 0.2 18.7 10.6 12.5 5.7 0.6 1.7 12.1 8.9 2.8 12.0 9.0 1.6 21.7 44.4 11.6 1.0 11.0 17.4 17.2 5.5 13.0 15.3 10.0 19.1 9.4 3.3 0.4 39.5 16.6 0.3 0.1 9.1 24.3 2.5 5.1 34.7 34.0 20.5 0.8 1.4 23.2 30.4 10.2 20.8 6.6 29.7 9.0 31.5 2.1 2.3 6.3 11.5 8.7 5.0 4.9 13.0 12.5 33.4 3.7 9.4 15.4 12.5 20.3 41.9 64.9 26.0 5.1 24.1 6.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.4 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.8 0.0 0.0 0.0 0.5 0.1 0.1 0.3 0.6 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 2.3 0.3 0.2 1.3 0.0 7.8 0.2 0.2 4.5 0.3 0.0 0.1 0.0 0.5 1.8 0.1 1.7 0.0 0.3 0.6 0.0 2.2 1.4 0.5 0.3 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 6.6 0.3 0.7 9.4 3.5 1.3 0.3 0.3 0.7 0.3 0.5 0.0 FAM83D "C20orf129, CHICA, dJ616B8.3" ENSG00000101447 "Family with sequence similarity 83 member D" Q9H4H8 20 38926312-38953106 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 84.7;intestine: 83.1;smooth muscle: 95.3" "Group enriched" "Detected in many" 4 "Basal squamous epithelial cells: 44.9;Erythroid cells: 72.6;Extravillous trophoblasts: 67.5;Squamous epithelial cells: 71.7;Syncytiotrophoblasts: 152.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "B-cells: 1.1;NK-cells: 1.1;T-cells: 2.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA049333, HPA060854" Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes Yes "Cluster 26: Non-specific - Mitochondria" "Cluster 37: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 61: Squamous epithelial cells - Keratinization" "Mitotic spindle" "Microtubules, Cytokinetic bridge, Cytosol" "HPA049333: AB_2680717, HPA060854: " "unprognostic (7.90e-3)" "unprognostic (4.34e-2)" "unprognostic (6.41e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (1.95e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (5.44e-6)" "prognostic unfavorable (9.69e-4)" "unprognostic (2.21e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (4.73e-5)" "unprognostic (3.52e-2)" "prognostic unfavorable (1.81e-14)" "unprognostic (2.57e-3)" "unprognostic (5.74e-2)" "unprognostic (2.82e-1)" "unprognostic (4.87e-2)" 1.6 1.8 0.8 7.2 1.6 23.3 1.1 0.9 1.4 4.1 0.2 83.1 8.4 1.0 1.6 84.7 1.0 13.6 1.0 0.9 0.5 5.7 3.7 5.2 4.5 0.5 0.4 0.5 0.4 0.2 0.4 3.4 0.5 16.2 8.6 0.2 7.8 1.7 0.2 10.2 34.7 95.3 0.5 1.9 44.9 5.0 0.5 6.6 1.0 0.2 12.2 27.0 17.1 0.9 112.2 67.3 52.0 44.0 5.8 6.5 93.6 49.3 30.2 94.7 57.4 103.4 49.7 28.3 47.6 32.1 73.4 93.1 71.8 83.9 87.9 9.4 28.6 32.6 50.7 75.2 4.7 14.6 16.5 3.3 4.2 54.6 31.4 11.4 52.7 12.3 29.6 39.5 54.4 59.7 22.7 21.3 43.2 64.4 85.1 21.8 96.0 15.6 27.6 28.0 24.3 40.2 143.0 117.4 20.6 48.1 73.6 14.9 25.4 62.4 76.4 71.6 110.1 12.0 19.6 29.0 28.1 21.2 46.7 0.0 0.0 0.0 0.2 0.1 0.9 0.6 1.0 1.1 0.0 1.1 1.1 1.4 0.0 1.1 0.1 0.0 2.0 0.5 0.8 1.6 0.9 1.4 0.9 0.5 0.5 0.4 0.5 0.5 0.5 0.9 3.9 0.0 1.3 0.3 2.3 2.3 5.8 7.0 44.9 0.0 2.8 9.0 0.8 1.5 18.0 0.0 0.0 17.3 6.3 6.5 0.0 0.1 0.5 1.1 1.6 2.2 1.8 72.6 3.7 0.0 67.5 2.7 18.3 2.1 0.0 8.2 1.8 5.7 4.8 0.0 1.2 6.0 4.1 1.6 0.5 0.6 0.3 2.6 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.1 6.0 0.0 12.5 1.6 1.7 8.3 4.5 0.0 19.7 0.3 4.0 15.7 18.3 71.7 1.8 152.6 5.2 0.3 10.2 4.1 FANCA "FA-H, FAA, FACA, FAH, FANCH" ENSG00000187741 "FA complementation group A" O15360 16 89737549-89816657 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.2;testis: 21.6" "Cell type enhanced" "Detected in many" "Spermatocytes: 44.1;Spermatogonia: 38.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA063236 Supported Nucleoplasm NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA063236: AB_2684966" "unprognostic (5.99e-2)" "unprognostic (5.68e-2)" "unprognostic (2.36e-1)" "unprognostic (5.12e-2)" "unprognostic (1.87e-1)" "unprognostic (7.11e-2)" "unprognostic (1.45e-4)" "unprognostic (9.21e-2)" "unprognostic (1.58e-2)" "unprognostic (2.05e-1)" "unprognostic (4.82e-3)" "unprognostic (8.48e-4)" "unprognostic (7.82e-10)" "unprognostic (3.67e-2)" "unprognostic (2.05e-1)" "unprognostic (2.94e-1)" "unprognostic (1.62e-1)" 1.4 1.9 1.7 6.7 1.9 20.2 1.9 2.4 3.3 2.1 1.5 5.5 5.2 1.2 0.8 6.6 2.0 1.2 1.6 1.8 1.2 2.9 6.1 3.4 12.5 1.4 1.1 1.4 1.9 1.4 1.9 4.1 1.5 1.7 6.2 1.0 2.1 0.6 0.7 5.2 5.6 2.1 1.1 6.7 3.6 21.6 1.5 8.1 1.7 0.6 13.5 2.2 2.7 1.9 23.2 34.8 40.8 35.7 2.6 5.2 31.2 28.2 15.3 46.5 19.5 30.6 37.3 56.2 12.9 9.8 15.5 34.7 27.7 21.1 48.8 13.4 46.5 16.6 49.1 63.4 1.7 17.1 17.5 1.7 2.2 37.8 12.0 6.6 14.9 28.0 40.9 16.9 24.6 53.6 34.6 73.7 26.5 31.5 21.3 61.4 32.8 10.3 11.8 21.5 36.3 19.7 41.9 12.3 5.4 23.3 22.4 30.4 11.1 37.0 38.9 20.9 30.0 15.1 19.0 56.3 17.5 37.8 36.1 2.5 7.4 9.9 4.2 8.5 3.0 7.0 2.4 3.7 6.2 4.6 0.6 2.6 9.4 8.2 9.2 0.4 9.2 4.2 1.7 1.9 2.4 3.3 1.8 1.2 1.4 1.1 1.5 1.1 1.5 1.9 1.5 0.0 1.1 0.7 9.6 3.4 1.6 2.6 0.0 8.1 3.0 2.0 2.9 0.0 3.5 16.5 10.4 16.0 12.3 5.1 1.9 2.0 5.9 2.8 3.5 2.1 1.8 20.8 10.0 1.6 9.9 3.3 9.2 3.4 2.5 19.0 5.3 4.7 8.8 3.3 5.7 8.1 2.0 4.1 3.1 4.1 1.5 6.8 0.0 1.0 3.0 1.1 21.6 3.0 1.7 1.9 1.7 0.0 21.1 1.3 6.6 10.4 6.4 7.7 0.0 2.7 3.5 44.1 38.5 3.8 1.8 25.3 9.3 6.8 11.4 2.6 FANCG "FAG, XRCC9" ENSG00000221829 "FA complementation group G" O15287 9 35073835-35079942 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 20.6;Spermatogonia: 20.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008105, HPA045335" Approved Approved "Nucleoli,Plasma membrane,Cytosol" NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" Nucleoli "CAB008105: AB_2231542, HPA045335: AB_2679292" "unprognostic (9.41e-2)" "unprognostic (2.62e-2)" "unprognostic (1.82e-1)" "unprognostic (1.05e-1)" "unprognostic (2.09e-1)" "unprognostic (5.83e-3)" "prognostic unfavorable (2.02e-4)" "unprognostic (8.92e-2)" "unprognostic (1.42e-2)" "unprognostic (2.27e-3)" "unprognostic (9.01e-2)" "unprognostic (5.62e-2)" "prognostic unfavorable (2.38e-7)" "unprognostic (1.14e-2)" "unprognostic (1.59e-1)" "unprognostic (1.24e-1)" "unprognostic (2.10e-1)" 3.4 3.1 2.8 5.1 2.8 12.4 4.5 3.6 3.8 5.1 2.1 4.3 4.9 4.2 2.3 5.9 5.8 3.3 1.9 2.7 2.7 3.9 2.9 3.3 7.7 2.8 2.7 6.2 6.3 4.7 3.0 4.5 2.7 3.9 4.0 2.4 4.3 4.1 2.3 6.5 4.6 4.5 2.5 5.5 4.1 6.4 2.7 12.2 4.0 1.7 6.9 3.5 4.6 3.4 34.7 40.7 30.4 28.3 6.4 10.2 25.0 23.6 16.3 44.9 42.5 20.1 21.2 33.4 15.8 7.7 33.1 20.5 25.3 22.0 17.6 38.7 14.8 24.5 45.5 13.2 1.8 24.5 26.9 8.1 4.1 39.5 18.2 8.0 23.8 40.7 15.7 44.3 23.5 31.5 43.2 34.5 32.5 26.4 30.1 43.8 35.2 23.1 10.9 14.6 14.4 26.1 15.7 22.3 8.3 13.4 28.4 17.2 13.4 21.0 42.8 28.3 33.1 12.4 24.0 20.6 19.2 18.5 30.1 10.5 0.7 6.7 6.1 2.2 5.3 5.6 4.8 4.6 1.9 5.4 3.6 3.8 1.1 7.8 2.0 4.2 8.2 3.1 2.8 2.8 3.6 3.8 2.7 2.7 2.8 2.7 2.7 2.5 2.7 3.4 3.2 3.2 4.6 6.8 4.9 4.5 6.1 3.9 10.2 4.7 5.9 5.0 1.5 2.8 3.3 3.7 4.2 15.0 4.1 3.0 3.9 4.9 0.4 2.3 3.8 4.4 1.8 11.6 3.0 2.3 20.6 5.1 1.5 3.6 14.0 10.3 4.2 1.1 7.7 5.0 3.3 4.1 2.0 1.3 4.7 0.6 3.4 2.3 3.6 1.0 2.8 4.0 3.1 0.5 4.1 1.9 2.4 4.1 14.1 4.4 3.5 2.3 1.3 3.1 0.0 3.0 3.9 14.7 20.7 8.5 2.6 6.6 4.9 2.8 6.7 5.2 FANCL "FAAP43, FLJ10335, PHF9, Pog" ENSG00000115392 "FA complementation group L" Q9NW38 2 58159243-58241372 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 81.4;Oligodendrocytes: 188.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033842, HPA036685, HPA036686" Supported Approved "Nuclear bodies,Vesicles" NA Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear bodies" Vesicles "CAB033842: AB_1122766, HPA036685: AB_10672474, HPA036686: AB_10670844" "unprognostic (3.02e-1)" "unprognostic (5.52e-2)" "unprognostic (2.19e-1)" "unprognostic (2.02e-3)" "unprognostic (6.24e-2)" "unprognostic (2.92e-2)" "prognostic unfavorable (2.81e-7)" "unprognostic (4.71e-2)" "unprognostic (2.63e-2)" "unprognostic (1.31e-2)" "unprognostic (3.50e-1)" "unprognostic (1.17e-2)" "prognostic unfavorable (1.12e-7)" "unprognostic (1.50e-1)" "unprognostic (1.39e-1)" "unprognostic (9.08e-3)" "prognostic favorable (7.80e-5)" 8.5 35.3 39.4 11.0 49.5 15.1 19.5 35.3 39.4 18.6 27.2 12.1 11.5 19.9 18.4 11.5 13.9 12.0 13.0 34.1 45.1 12.2 21.7 9.6 14.8 51.6 40.3 24.8 14.5 14.0 44.3 12.5 55.4 14.7 14.8 24.6 18.7 10.7 9.1 17.9 12.8 13.5 40.9 16.8 13.1 19.1 41.2 13.2 17.1 9.1 12.6 11.7 14.6 68.6 48.6 35.0 69.4 34.0 11.9 15.1 36.9 34.8 21.5 33.8 43.5 30.9 59.4 33.4 43.8 11.4 46.3 27.5 39.0 26.4 56.0 78.8 61.7 54.8 49.5 42.1 13.0 53.3 29.0 11.8 12.4 24.8 9.7 29.9 27.0 23.5 51.9 29.6 23.2 24.6 18.9 65.8 75.2 77.4 7.2 35.2 52.5 26.1 29.9 47.2 78.1 39.3 49.5 20.2 33.8 37.0 18.7 35.4 15.9 30.0 45.0 22.3 39.0 30.4 20.6 19.7 63.7 35.7 46.6 3.2 3.0 4.9 3.7 5.6 3.0 9.1 3.2 4.2 5.9 9.3 1.0 2.3 0.8 7.6 4.3 5.3 4.8 2.2 39.4 49.5 35.3 39.4 34.1 45.1 51.6 40.3 55.4 40.9 41.2 68.6 16.7 19.2 20.0 18.6 9.4 10.3 13.9 26.1 11.4 16.6 12.5 15.4 16.4 8.6 16.1 9.2 4.2 29.1 4.8 7.2 11.7 9.7 2.5 11.1 15.8 14.8 9.0 14.5 45.0 4.2 14.0 12.2 15.3 6.2 10.8 25.8 13.2 12.5 10.9 8.4 38.4 15.0 30.5 6.3 4.6 3.6 10.8 7.0 26.6 34.7 6.8 22.8 3.1 81.4 188.9 4.6 13.3 14.3 9.7 6.2 21.7 5.7 23.2 18.7 13.1 10.8 12.4 52.6 37.9 9.5 6.8 7.4 5.6 13.2 16.0 9.3 FBXO5 "EMI1, FBX5, Fbxo31" ENSG00000112029 "F-box protein 5" Q9UKT4 6 152970519-152983579 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 44.1;lymphoid tissue: 27.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 36.0;Extravillous trophoblasts: 30.5;Spermatocytes: 32.3;Spermatogonia: 26.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB008106, HPA029048" Approved Supported Nucleoplasm NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB008106: AB_828450, HPA029048: AB_10602132" "unprognostic (1.22e-2)" "unprognostic (7.21e-2)" "unprognostic (4.61e-3)" "unprognostic (1.24e-2)" "unprognostic (5.92e-2)" "unprognostic (2.94e-2)" "unprognostic (2.43e-8)" "unprognostic (2.46e-2)" "unprognostic (1.55e-2)" "unprognostic (7.32e-2)" "unprognostic (2.89e-1)" "unprognostic (5.86e-2)" "unprognostic (1.25e-9)" "prognostic favorable (8.65e-4)" "unprognostic (1.20e-1)" "unprognostic (1.72e-1)" "unprognostic (1.51e-1)" 3.1 3.1 1.5 7.3 1.6 44.1 4.5 2.6 2.1 4.0 1.9 5.0 4.6 5.3 4.5 3.7 3.0 2.6 1.8 1.4 1.7 3.1 4.4 3.4 14.9 1.6 1.6 4.1 3.0 2.3 2.1 6.3 1.7 3.0 5.1 3.3 2.7 2.9 0.9 4.3 4.3 5.0 1.6 5.5 4.6 3.9 1.8 27.3 4.4 2.6 14.6 4.0 3.0 2.0 33.7 17.2 70.8 48.1 5.3 10.8 22.6 79.9 35.5 58.7 65.6 35.6 19.8 81.6 23.9 21.3 39.7 31.4 56.4 26.7 70.0 44.2 50.6 82.3 24.1 38.7 10.2 74.4 48.6 7.7 4.9 39.8 30.9 14.3 27.3 42.3 88.2 74.5 53.9 25.7 85.2 47.6 41.5 25.8 25.0 71.0 56.8 52.8 20.8 18.0 46.1 47.9 56.6 30.2 15.6 24.7 21.8 68.7 20.6 43.9 57.4 51.1 94.8 24.9 29.5 120.4 31.9 54.3 54.2 0.0 1.9 0.0 2.8 2.5 4.0 5.1 4.7 5.2 3.7 5.0 4.6 4.8 0.0 7.1 3.2 4.3 6.6 2.5 1.5 1.6 2.6 2.1 1.4 1.7 1.6 1.6 1.7 1.6 1.8 2.0 6.0 0.0 1.1 1.3 9.8 9.9 3.7 4.0 7.4 3.2 5.7 5.2 1.8 2.8 3.9 1.8 6.2 15.2 13.5 2.6 3.9 3.0 0.4 2.3 10.5 5.7 4.8 36.0 1.0 1.6 30.5 9.1 7.7 4.0 2.5 16.6 5.0 1.9 7.9 1.7 0.9 6.1 2.0 3.2 6.1 0.1 4.4 5.3 1.8 1.9 4.2 4.1 9.2 1.5 2.1 1.5 0.5 6.0 24.7 3.6 1.5 3.6 1.9 3.6 13.1 8.6 8.9 32.3 26.1 10.2 5.3 5.9 7.9 8.0 6.3 2.0 FEN1 "FEN-1, MF1, RAD2" ENSG00000168496 "Flap structure-specific endonuclease 1" P39748 11 61792911-61797238 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "Endonuclease, Exonuclease, Hydrolase, Nuclease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 46.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 87.5;Extravillous trophoblasts: 70.9;Spermatocytes: 61.0;Spermatogonia: 62.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002262, HPA006748" Enhanced Enhanced Nucleoplasm,Nucleoli NA Yes 160000 "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "CAB002262: AB_563729, HPA006748: AB_1848494" "unprognostic (1.82e-1)" "unprognostic (2.71e-2)" "unprognostic (3.76e-2)" "unprognostic (2.77e-1)" "unprognostic (1.26e-1)" "unprognostic (6.45e-2)" "prognostic unfavorable (3.39e-6)" "unprognostic (1.50e-2)" "unprognostic (9.82e-2)" "prognostic favorable (7.85e-4)" "unprognostic (2.82e-3)" "unprognostic (5.86e-2)" "prognostic unfavorable (5.73e-6)" "prognostic favorable (9.46e-4)" "unprognostic (1.10e-1)" "unprognostic (4.49e-3)" "unprognostic (4.04e-2)" 5.9 10.4 7.8 21.3 7.8 39.5 10.2 10.9 9.9 6.2 9.6 15.5 11.2 6.3 7.1 14.2 5.7 4.3 6.6 8.0 7.7 5.8 9.9 5.6 34.0 10.0 8.3 3.9 6.8 5.6 8.3 12.9 10.7 6.2 16.1 17.4 6.1 5.9 13.1 9.6 11.4 8.9 6.8 12.8 8.4 19.1 9.1 46.0 4.8 9.6 37.4 8.1 4.9 8.1 154.6 139.7 149.3 81.3 14.9 18.0 94.9 133.3 76.1 160.9 181.4 123.4 112.8 222.6 100.3 57.3 150.5 158.3 214.3 117.7 163.3 117.8 117.6 117.6 187.7 127.3 11.0 184.7 115.4 12.7 15.8 148.1 39.0 23.3 63.1 122.1 181.3 155.1 136.0 195.4 259.7 165.4 165.3 120.3 134.7 173.8 173.7 228.9 64.4 144.7 170.0 140.7 89.6 115.0 79.1 70.1 167.4 127.1 43.2 141.5 178.1 182.3 134.6 120.4 204.3 228.9 98.4 121.9 124.6 24.7 6.7 14.2 16.2 12.9 16.8 14.4 12.3 15.1 8.0 14.8 14.0 13.8 2.7 20.0 12.9 24.5 25.2 10.3 7.8 7.8 10.9 9.9 8.0 7.7 10.0 8.3 10.7 6.8 9.1 8.1 2.7 0.0 2.2 0.3 14.0 10.3 5.2 18.2 7.4 23.8 7.4 7.4 5.8 5.7 7.7 0.0 12.5 53.0 15.9 6.7 7.9 17.3 21.7 4.2 5.5 5.5 4.8 87.5 2.0 12.2 70.9 8.6 7.1 6.3 0.0 18.6 1.1 7.2 25.7 15.2 2.4 8.0 18.3 5.4 6.8 14.4 5.6 6.2 5.4 0.0 12.4 31.3 13.4 1.5 3.1 12.2 9.4 7.2 45.3 6.5 3.7 5.7 6.4 23.3 0.0 6.8 12.2 61.0 62.1 11.3 6.1 30.9 11.0 9.0 22.0 5.2 FHL2 "DRAL, SLIM3" ENSG00000115641 "Four and a half LIM domains 2" Q14192 2 105357712-105438513 "Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "heart muscle: 1421.4;ovary: 535.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 1077.5;Extravillous trophoblasts: 585.9;Granulosa cells: 851.4;Leydig cells: 567.0;Peritubular cells: 1049.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 5.7" "Group enriched" "Detected in many" 6 "granulocytes: 5.7;T-cells: 2.7" "Cell line enhanced" "Detected in many" "LHCN-M2: 534.6;RPTEC TERT1: 489.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005922, HPA006028, CAB008368" Enhanced Enhanced "Actin filaments,Focal adhesion sites" NA Yes 14000 "Cluster 18: Basophils - Vesicular transport" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments, Focal adhesion sites" "CAB008368: AB_591383, HPA005922: AB_1078860, HPA006028: AB_1078858" "unprognostic (1.04e-1)" "unprognostic (1.63e-3)" "unprognostic (3.30e-1)" "unprognostic (3.42e-2)" "unprognostic (5.89e-2)" "prognostic unfavorable (2.01e-4)" "unprognostic (2.80e-2)" "unprognostic (1.02e-3)" "unprognostic (1.81e-1)" "unprognostic (2.42e-2)" "unprognostic (3.34e-2)" "unprognostic (8.11e-2)" "prognostic unfavorable (6.42e-5)" "unprognostic (2.06e-1)" "unprognostic (3.49e-1)" "unprognostic (9.92e-3)" "unprognostic (4.73e-2)" 68.3 70.2 10.4 28.9 13.2 17.0 65.4 7.6 18.2 101.9 15.0 75.2 48.5 105.1 33.8 55.4 55.8 81.5 1421.4 18.9 7.4 55.2 22.1 17.5 17.2 6.7 7.2 535.4 9.1 8.2 29.3 79.3 7.0 88.8 56.8 8.5 45.3 63.8 67.5 44.2 50.4 91.5 7.5 20.1 94.9 50.9 7.9 22.8 41.3 118.6 13.9 105.5 47.2 12.2 156.8 36.1 20.9 0.8 65.2 81.7 196.4 289.3 75.9 182.2 216.7 65.6 237.6 0.4 23.7 353.6 223.8 47.7 31.4 262.4 204.2 6.5 23.9 108.7 42.9 49.0 257.6 0.4 23.5 171.7 142.2 286.0 188.1 360.8 374.4 18.0 29.0 8.9 534.6 5.6 25.8 1.0 44.1 108.3 113.2 0.4 31.6 4.3 489.8 108.4 1.0 6.9 109.2 48.1 76.9 20.5 60.7 3.9 183.1 130.4 134.1 146.4 236.0 3.3 0.6 0.7 208.1 0.6 138.5 5.7 0.4 0.4 1.1 0.2 0.7 0.6 0.9 2.0 0.4 0.5 0.7 1.5 2.2 0.7 0.2 0.6 2.7 1.5 10.4 13.2 7.6 18.2 18.9 7.4 6.7 7.2 7.0 7.5 7.9 12.2 15.7 9.6 5.1 0.7 1.0 468.5 1077.5 342.5 389.9 9.5 59.8 126.2 362.1 15.7 91.0 29.5 2.1 220.4 1.7 212.6 3.9 100.7 5.7 44.8 40.4 27.4 58.2 63.5 46.3 117.9 585.9 96.1 186.1 32.5 10.2 851.4 17.2 9.2 25.3 0.0 4.9 169.8 73.2 0.6 31.8 17.3 567.0 10.4 23.2 25.3 2.7 1.6 0.0 0.5 1.6 234.5 258.2 1049.0 6.7 198.2 51.7 28.1 19.1 13.0 216.9 60.6 171.0 9.1 17.7 124.5 296.9 178.7 7.7 193.5 55.8 536.2 FOSL1 fra-1 ENSG00000175592 "FOS like 1, AP-1 transcription factor subunit" P15407 11 65892049-65900573 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 56.4;urinary bladder: 84.3" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 338.0;Basal prostatic cells: 398.5;Basal squamous epithelial cells: 281.1;Prostatic glandular cells: 196.9;Squamous epithelial cells: 210.4;Suprabasal keratinocytes: 339.5;Urothelial cells: 456.4" "Cancer enhanced" "Detected in all" "head and neck cancer: 51.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "myeloid DC: 3.4" "Lineage enriched" "Detected in single" 4 "dendritic cells: 3.4" "Cell line enhanced" "Detected in many" "PC-3: 829.4;U-2197: 520.1;WM-115: 1123.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB004396, HPA030728" Enhanced Supported Nucleoplasm NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 17: WM-115 - Nervous system development" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "CAB004396: AB_627632, HPA030728: " "unprognostic (2.88e-2)" "unprognostic (1.56e-1)" "unprognostic (9.46e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.80e-4)" "prognostic unfavorable (2.05e-4)" "unprognostic (2.70e-1)" "prognostic unfavorable (1.95e-4)" "unprognostic (1.12e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (9.26e-5)" "unprognostic (7.85e-2)" "prognostic unfavorable (6.40e-6)" "unprognostic (2.23e-1)" "unprognostic (1.53e-1)" "unprognostic (2.28e-1)" "unprognostic (2.82e-2)" 56.4 11.2 1.2 7.7 1.3 26.8 10.5 2.2 4.3 6.0 1.0 7.4 1.0 3.5 0.1 48.9 8.5 29.6 11.9 1.6 1.7 12.6 5.6 16.7 0.3 1.9 1.4 1.7 12.9 0.5 4.8 2.7 2.1 6.4 1.9 0.6 11.0 0.8 4.1 25.2 5.5 4.7 1.0 1.7 21.0 0.9 1.9 2.7 5.3 0.3 2.1 84.3 13.8 1.0 324.3 43.8 5.4 20.4 45.7 44.4 45.0 288.5 257.2 239.7 131.7 14.2 252.6 0.5 65.1 199.7 379.6 60.6 19.6 227.4 210.8 9.7 0.7 20.6 4.5 34.9 57.0 13.3 6.9 18.8 23.1 191.1 297.1 117.9 80.4 0.2 48.8 1.7 320.9 12.3 0.3 26.5 21.5 27.0 829.4 1.5 25.7 1.3 116.7 20.4 0.4 0.5 18.2 0.8 229.0 13.0 1.0 12.1 200.6 282.5 62.7 520.1 423.8 0.3 1.4 0.9 389.7 4.9 1123.6 0.0 0.8 0.0 0.1 0.5 0.0 0.0 0.2 0.1 3.4 0.0 0.2 0.0 0.5 0.0 0.3 0.4 0.0 0.5 1.2 1.3 2.2 4.3 1.6 1.7 1.9 1.4 2.1 1.0 1.9 1.0 15.2 6.4 4.4 0.3 2.0 338.0 398.5 56.2 281.1 0.0 27.6 12.2 1.0 4.3 26.2 0.0 0.0 1.3 4.3 11.8 0.0 25.1 0.3 24.4 12.2 30.1 11.3 0.8 0.1 3.5 4.3 45.8 74.9 56.3 9.5 0.3 6.1 0.4 1.9 0.0 0.1 6.8 10.2 1.0 46.6 0.0 0.3 15.5 44.4 1.0 1.1 0.1 0.0 0.5 0.2 39.0 11.1 0.0 6.2 196.9 1.2 0.2 10.7 0.0 0.0 32.4 26.1 0.4 0.7 210.4 339.5 17.6 6.8 0.1 4.2 456.4 FOXM1 "FKHL16, HFH-11, HNF-3, INS-1, MPHOSPH2, MPP2, TGT3, trident" ENSG00000111206 "Forkhead box M1" Q08050 12 2857680-2877174 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.0;lymphoid tissue: 32.2;testis: 21.4" "Cell type enhanced" "Detected in many" "Early spermatids: 22.4;Erythroid cells: 18.7;Extravillous trophoblasts: 18.2;Late spermatids: 25.5;Plasma cells: 19.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" CAB017832 Uncertain Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli, Nucleoli rim" Cytosol "CAB017832: " "unprognostic (3.18e-2)" "unprognostic (1.69e-1)" "unprognostic (1.22e-2)" "unprognostic (1.09e-2)" "unprognostic (4.30e-2)" "unprognostic (3.75e-2)" "prognostic unfavorable (1.95e-6)" "prognostic unfavorable (2.92e-4)" "unprognostic (1.01e-2)" "unprognostic (3.25e-2)" "prognostic unfavorable (3.03e-5)" "unprognostic (6.09e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.80e-2)" "unprognostic (1.87e-1)" "unprognostic (1.29e-1)" "unprognostic (1.94e-1)" 1.9 1.1 0.4 9.4 0.5 25.0 1.8 0.8 0.8 1.7 0.2 10.5 9.7 1.7 0.2 11.1 0.8 1.5 0.5 0.8 0.3 0.7 1.2 1.8 11.3 0.4 0.9 0.3 0.4 0.4 0.1 6.1 0.6 0.7 12.5 1.1 1.9 0.8 0.6 6.4 8.8 7.5 0.1 3.1 5.2 21.4 1.0 32.2 0.9 0.3 15.2 3.0 3.2 0.6 133.0 129.5 101.3 92.2 14.2 19.0 129.2 84.0 80.4 165.2 147.2 166.9 114.8 84.5 17.7 119.8 188.5 100.2 153.1 76.1 160.0 159.8 80.3 94.7 121.6 71.6 2.0 79.2 75.0 9.9 8.3 154.4 106.1 39.1 117.8 96.8 55.6 184.9 130.5 122.6 108.3 36.8 225.6 136.1 95.4 77.3 149.8 44.1 38.1 82.7 56.3 89.1 106.7 90.4 46.6 189.4 87.1 87.8 48.0 134.3 200.5 160.4 300.4 24.7 44.3 122.1 63.1 74.3 147.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.5 0.8 0.8 0.8 0.3 0.4 0.9 0.6 0.1 1.0 0.6 0.1 0.0 1.3 0.7 2.4 2.9 1.3 1.0 1.2 2.0 1.7 1.3 0.5 1.5 0.8 1.8 4.2 7.1 0.8 6.6 1.9 0.2 22.4 1.2 2.1 2.5 0.0 18.7 1.1 0.0 18.2 3.2 10.2 2.4 0.0 15.4 3.6 0.8 9.1 5.0 0.6 7.5 2.0 4.2 1.2 25.5 0.9 2.4 0.0 0.0 1.1 0.6 1.0 0.5 1.0 0.3 0.3 0.7 19.9 1.0 1.4 0.4 0.2 4.0 0.0 1.2 3.0 15.0 9.9 10.2 1.4 1.9 3.3 0.9 12.9 1.9 FSCN1 "FLJ38511, p55, SNL" ENSG00000075618 "Fascin actin-bundling protein 1" Q16658 7 5592816-5606655 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 256.5;Hofbauer cells: 274.2;monocytes: 1028.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 2.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 600.3;Hep G2: 464.9;K-562: 533.6;NB-4: 600.9;PC-3: 508.2;SH-SY5Y: 482.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000121, HPA005723, CAB035991, HPA050654" Enhanced Supported "Plasma membrane,Cytosol" NA Yes 4300000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 3: Monocytes - Immune response regulation" Cytosol "Plasma membrane" "CAB000121: AB_2278596, CAB035991: , HPA005723: AB_1849159, HPA050654: AB_2681203" "unprognostic (1.91e-1)" "unprognostic (2.03e-2)" "unprognostic (3.12e-2)" "unprognostic (5.00e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (5.76e-4)" "unprognostic (2.16e-3)" "prognostic unfavorable (2.28e-4)" "unprognostic (6.31e-2)" "unprognostic (1.25e-1)" "unprognostic (3.27e-3)" "unprognostic (1.54e-1)" "prognostic unfavorable (8.15e-7)" "unprognostic (1.21e-2)" "unprognostic (8.57e-2)" "unprognostic (1.05e-2)" "unprognostic (6.93e-3)" 27.5 39.7 41.5 31.1 62.2 8.3 24.9 26.3 57.2 33.7 10.7 12.1 4.4 19.7 0.7 69.4 15.6 7.6 15.8 39.4 28.2 17.3 8.3 27.6 14.5 49.4 42.7 47.7 5.5 2.3 20.2 27.9 22.8 10.3 1.7 3.4 23.8 2.4 7.3 56.3 12.6 5.7 20.9 55.6 9.3 42.5 79.0 9.0 25.6 2.1 8.3 20.4 41.6 77.1 62.3 139.3 91.2 326.3 34.8 65.4 600.3 144.2 62.4 24.2 26.1 98.5 15.6 1.3 172.0 63.5 24.3 231.3 52.2 229.9 2.1 70.6 28.7 4.8 142.0 464.9 18.0 0.2 13.9 40.8 66.6 46.1 37.2 40.4 118.3 0.7 533.6 0.9 31.6 6.9 2.0 600.9 238.4 4.2 508.2 140.0 22.3 2.3 34.9 5.9 73.1 482.4 121.0 2.6 5.3 58.5 3.9 38.4 246.4 167.4 289.3 99.1 151.0 0.9 0.8 0.7 107.8 0.6 317.2 0.0 0.8 0.0 0.0 0.2 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.7 41.5 62.2 26.3 57.2 39.4 28.2 49.4 42.7 22.8 20.9 79.0 77.1 90.0 3.2 4.1 1.6 8.3 181.2 26.7 75.1 189.5 9.4 32.3 44.3 10.4 1.5 13.4 1.8 0.0 6.7 10.8 3.9 0.0 12.8 14.3 8.0 37.8 120.6 42.1 28.0 12.1 5.1 110.8 48.9 10.7 10.1 16.5 256.5 84.6 0.8 274.2 0.0 10.9 5.4 8.2 28.0 136.1 12.3 25.4 27.4 51.6 23.4 1028.2 73.5 0.0 4.5 43.2 15.5 1.1 9.1 4.2 7.5 0.4 0.4 2.9 2.6 0.0 29.7 46.3 5.7 8.0 121.2 147.2 14.6 12.2 8.3 2.6 28.0 FSTL3 "FLRG, FSRP" ENSG00000070404 "Follistatin like 3" O95633 19 676392-683392 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Osteogenesis, Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Extravillous trophoblasts: 3647.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 164.7;hTCEpi: 181.2;SiHa: 341.5;U-2197: 173.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB024899, HPA045378" Approved Supported Nucleoplasm "Secreted in other tissues" NA Yes 7000000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "CAB024899: , HPA045378: AB_2679300" "unprognostic (9.86e-3)" "unprognostic (1.32e-3)" "prognostic unfavorable (3.01e-4)" "prognostic unfavorable (3.03e-4)" "unprognostic (2.19e-3)" "unprognostic (1.51e-3)" "unprognostic (8.64e-3)" "prognostic unfavorable (4.61e-7)" "unprognostic (9.50e-2)" "prognostic unfavorable (1.65e-4)" "unprognostic (3.50e-2)" "unprognostic (5.91e-2)" "unprognostic (1.03e-3)" "unprognostic (7.22e-3)" "unprognostic (3.07e-1)" "unprognostic (3.75e-1)" "unprognostic (5.89e-3)" 82.9 163.3 16.6 24.1 15.3 13.3 62.4 13.3 19.8 75.6 16.0 82.7 7.7 62.0 6.1 22.0 70.2 16.5 124.1 16.4 17.3 55.9 26.2 132.7 5.5 22.6 16.0 63.8 49.3 3.2 28.9 179.4 17.9 74.9 5.9 2.4 21.1 22.1 11.7 32.3 36.5 42.4 16.7 22.6 43.2 75.2 18.1 2.3 37.9 4.9 1.6 70.5 63.1 18.9 9.5 74.0 5.1 3.7 22.3 56.4 164.7 126.1 18.5 30.7 11.3 27.1 14.4 4.1 49.4 84.7 17.6 65.2 4.1 106.4 10.1 7.8 8.7 3.5 110.2 22.4 95.6 6.7 12.0 70.7 181.2 34.0 140.2 79.3 5.5 3.9 8.2 5.3 46.7 33.1 2.4 4.0 6.2 62.0 26.2 7.2 3.4 8.7 43.1 1.7 3.3 5.7 341.5 6.9 4.3 6.4 6.2 3.5 75.5 30.6 106.6 173.4 46.9 8.5 4.4 2.3 4.7 20.0 14.2 0.0 1.9 0.0 0.4 1.8 0.0 0.1 0.6 0.4 0.9 0.3 1.0 0.6 0.0 0.2 1.4 0.3 0.0 0.9 16.6 15.3 13.3 19.8 16.4 17.3 22.6 16.0 17.9 16.7 18.1 18.9 4.6 19.2 1.9 40.5 1.5 14.5 31.0 11.7 1.8 1.3 11.3 7.9 16.7 32.9 4.4 9.2 0.0 53.9 1.0 1.1 7.9 86.1 8.8 6.4 14.8 8.7 1.2 1.7 9.8 64.3 3647.6 59.6 2.0 18.3 0.0 5.7 16.4 1.9 77.1 3.3 8.4 1.0 0.0 3.7 4.8 7.6 61.2 7.4 5.4 2.8 10.6 6.6 1.0 6.0 5.5 306.5 0.2 26.7 1.0 78.0 1.2 17.7 3.1 1.1 46.0 22.4 57.0 4.6 5.6 4.3 7.7 792.0 2.0 3.6 2.5 30.7 FZR1 "CDC20C, CDH1, FZR, FZR2, HCDH, HCDH1, KIAA1242" ENSG00000105325 "Fizzy and cell division cycle 20 related 1" Q9UM11 19 3506311-3538334 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 104.2;Late spermatids: 208.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043536 Approved Supported "Nucleoplasm,Nuclear membrane" NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear membrane" "HPA043536: AB_10968058" "unprognostic (2.78e-1)" "prognostic favorable (1.75e-4)" "unprognostic (1.15e-1)" "prognostic favorable (2.57e-4)" "unprognostic (1.60e-1)" "unprognostic (1.36e-2)" "unprognostic (9.20e-2)" "unprognostic (1.61e-1)" "unprognostic (9.70e-2)" "unprognostic (1.18e-1)" "unprognostic (4.15e-3)" "unprognostic (1.41e-2)" "unprognostic (3.75e-1)" "unprognostic (5.41e-3)" "unprognostic (1.75e-1)" "unprognostic (9.04e-2)" "unprognostic (1.04e-1)" 14.8 25.2 17.0 9.3 14.0 33.5 16.4 19.1 17.2 21.3 5.2 17.2 21.9 19.3 4.0 23.5 18.2 9.4 13.0 16.7 17.1 18.1 23.5 15.6 11.4 19.2 17.3 22.9 17.3 10.9 34.1 8.9 19.3 19.1 3.7 5.6 19.7 10.5 18.5 26.2 18.4 6.3 12.0 18.8 15.6 52.7 15.8 13.9 24.0 7.5 7.0 16.2 20.9 13.5 44.0 25.7 24.3 22.4 7.5 10.4 18.9 26.7 17.8 31.0 24.2 26.2 21.1 24.3 13.5 19.7 15.0 25.2 13.7 23.4 6.2 32.9 23.5 11.6 19.5 26.2 13.4 20.9 23.8 9.8 13.5 18.8 11.2 11.7 18.4 23.0 21.0 41.1 16.1 22.8 37.5 15.2 20.5 13.6 20.1 28.0 20.6 23.6 15.6 21.6 22.3 25.0 24.1 17.5 13.1 5.5 18.2 19.1 24.9 17.6 21.3 42.9 47.4 42.9 10.8 18.5 24.4 41.5 22.3 1.1 0.7 2.0 1.0 0.7 0.6 1.0 1.0 0.7 0.6 0.8 0.6 0.8 1.3 1.2 0.5 0.5 0.9 0.6 17.0 14.0 19.1 17.2 16.7 17.1 19.2 17.3 19.3 12.0 15.8 13.5 8.1 0.0 5.0 6.5 15.4 17.8 35.8 10.6 6.2 20.7 14.5 11.2 3.4 17.2 8.6 12.9 10.4 21.9 11.0 25.8 5.9 16.5 104.2 14.1 8.2 11.0 21.6 26.5 6.3 14.9 14.2 10.1 26.5 14.3 3.8 20.4 10.0 17.9 16.4 30.3 9.1 18.1 18.3 7.9 11.4 208.2 12.8 11.9 12.4 3.7 18.1 8.5 9.2 6.6 10.4 28.1 17.0 9.4 13.7 20.6 17.4 13.5 10.8 15.6 6.6 7.3 12.9 58.4 15.8 11.9 22.6 45.4 11.9 15.6 16.1 28.3 G2E3 "FLJ20333, KIAA1333, PHF7B" ENSG00000092140 "G2/M-phase specific E3 ubiquitin protein ligase" Q7L622 14 30559158-30620064 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 42.3" "Group enriched" "Detected in all" 6 "Early spermatids: 722.5;Late spermatids: 233.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001601 Uncertain Approved "Golgi apparatus,Vesicles,Cytosol" NA Yes "Cluster 18: Basophils - Vesicular transport" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "Golgi apparatus, Vesicles" "HPA001601: AB_1079198" "unprognostic (4.75e-2)" "unprognostic (6.31e-2)" "unprognostic (2.27e-2)" "unprognostic (4.86e-2)" "unprognostic (9.10e-2)" "unprognostic (3.99e-2)" "unprognostic (5.44e-6)" "unprognostic (1.17e-2)" "unprognostic (2.81e-2)" "unprognostic (1.86e-1)" "unprognostic (3.13e-2)" "unprognostic (1.35e-1)" "unprognostic (1.00e-1)" "unprognostic (1.67e-1)" "unprognostic (1.23e-1)" "unprognostic (2.32e-2)" "unprognostic (2.12e-2)" 4.8 3.2 2.1 6.4 7.0 10.0 6.4 11.6 5.5 6.4 0.7 5.6 5.0 6.3 3.7 6.2 4.8 3.8 4.8 2.4 5.6 4.5 5.2 4.5 9.1 3.1 2.5 6.1 5.2 5.6 2.7 6.3 2.7 5.1 5.3 13.8 4.9 4.6 3.0 5.9 4.9 6.2 1.0 6.3 5.3 42.3 7.0 14.3 6.6 3.9 8.9 4.9 3.9 9.6 37.9 15.6 33.7 16.1 11.2 15.0 30.5 31.9 12.9 20.2 22.9 17.1 20.5 32.9 10.9 18.4 15.9 29.7 36.4 18.8 42.2 25.7 15.7 19.6 17.1 31.0 10.3 34.0 22.5 8.1 7.4 15.1 34.9 18.3 22.9 22.5 21.2 24.2 29.0 21.9 22.6 9.6 31.2 27.5 32.7 21.4 0.0 8.2 10.5 22.3 28.4 19.9 27.7 16.0 7.9 20.5 19.1 12.5 17.3 19.7 21.9 16.9 21.9 14.1 47.7 38.8 5.4 16.6 29.2 20.2 6.5 12.9 7.6 8.5 10.1 9.2 7.4 6.3 5.6 9.9 9.2 7.8 5.9 6.5 11.3 6.8 6.6 4.1 2.1 7.0 11.6 5.5 2.4 5.6 3.1 2.5 2.7 1.0 7.0 9.6 22.6 19.2 9.0 17.9 32.9 21.9 22.5 11.8 26.7 34.9 13.0 10.8 10.0 12.8 13.6 5.5 25.0 17.8 23.0 9.0 9.8 8.9 722.5 13.9 26.6 17.0 13.8 42.7 45.3 7.1 22.7 20.6 14.3 14.1 17.1 23.3 13.2 7.5 14.2 35.3 38.4 14.7 14.2 13.9 12.4 233.9 16.4 16.5 8.8 24.4 16.2 15.5 32.0 41.7 43.1 10.7 9.4 14.3 14.4 22.5 5.6 12.0 10.9 33.4 52.6 18.0 18.6 69.8 42.7 20.7 25.4 10.0 24.9 11.9 12.4 20.6 GABPB1 "E4TF1-47, GABPB, GABPB2" ENSG00000104064 "GA binding protein transcription factor subunit beta 1" Q06547 15 50275389-50355408 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019653, HPA067444" Supported Supported "Nucleoplasm,Cytoplasmic bodies" NA Yes "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Cytoplasmic bodies" "HPA019653: AB_1849370, HPA067444: AB_2685842" "unprognostic (7.79e-3)" "unprognostic (2.42e-2)" "unprognostic (3.84e-1)" "unprognostic (1.92e-1)" "unprognostic (9.33e-2)" "unprognostic (3.99e-2)" "unprognostic (3.25e-2)" "unprognostic (5.65e-2)" "unprognostic (1.86e-2)" "unprognostic (8.94e-3)" "unprognostic (1.23e-1)" "unprognostic (4.54e-3)" "prognostic unfavorable (2.53e-4)" "unprognostic (3.18e-2)" "unprognostic (2.37e-1)" "unprognostic (1.13e-1)" "unprognostic (3.93e-3)" 14.1 7.5 5.5 13.6 6.1 34.7 11.5 11.1 7.1 8.5 5.8 9.0 7.6 10.4 9.5 8.0 8.6 9.2 7.1 5.7 5.7 7.4 13.9 9.3 18.8 6.2 5.2 8.2 7.4 9.8 4.7 14.3 6.3 9.6 10.7 8.1 8.5 6.9 7.4 8.2 7.9 10.0 5.3 11.9 8.8 16.1 5.8 24.8 9.6 8.1 20.1 16.8 6.9 9.2 25.4 28.6 41.0 32.0 10.6 14.8 54.7 32.5 25.5 37.6 32.9 48.9 20.3 33.0 19.3 26.9 29.7 40.8 37.2 27.9 47.5 46.1 22.2 39.2 29.3 33.7 25.3 37.9 29.1 19.7 26.8 35.3 45.6 21.0 66.9 35.6 36.6 40.4 25.4 58.1 56.5 34.1 28.2 27.8 19.2 68.6 29.8 31.7 22.9 31.7 38.9 32.0 29.0 27.0 33.4 38.9 23.5 37.1 32.1 34.2 28.3 60.4 58.9 28.6 42.0 57.8 21.1 34.5 35.2 44.5 16.2 32.7 19.8 20.1 26.5 31.6 19.4 21.4 22.4 26.4 17.7 20.5 16.1 27.3 15.7 17.7 27.9 20.2 5.5 6.1 11.1 7.1 5.7 5.7 6.2 5.2 6.3 5.3 5.8 9.2 18.2 9.6 11.2 10.7 80.0 47.2 126.7 15.1 23.9 43.1 10.1 9.4 17.7 24.3 7.2 7.3 35.5 43.2 47.3 11.4 3.9 12.2 79.5 8.3 11.9 38.0 50.4 38.7 13.9 7.6 50.5 33.2 23.9 10.9 47.0 8.6 41.7 30.6 37.0 37.0 12.3 24.9 12.2 73.4 22.3 33.3 57.8 42.2 19.6 15.9 54.0 32.4 120.5 22.1 19.1 14.6 21.6 38.4 58.7 89.3 21.4 8.4 8.7 45.8 26.3 64.0 32.5 28.9 34.0 32.7 35.8 55.4 77.2 6.7 27.8 116.6 GADD45A "DDIT1, GADD45" ENSG00000116717 "Growth arrest and DNA damage inducible alpha" P24522 1 67685201-67688334 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, Growth arrest" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 240.5" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 858.9;Basal prostatic cells: 2807.1;Glandular and luminal cells: 982.6;Urothelial cells: 1740.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 48.4" "Group enriched" "Detected in all" 5 "granulocytes: 48.4;T-cells: 18.6" "Cell line enhanced" "Detected in all" "HHSteC: 365.9;hTERT-HME1: 577.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053420 Supported "Nuclear speckles" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear speckles" "HPA053420: AB_2682144" "unprognostic (1.36e-2)" "unprognostic (3.29e-2)" "unprognostic (9.58e-2)" "unprognostic (3.76e-3)" "unprognostic (5.81e-2)" "unprognostic (1.36e-2)" "unprognostic (1.57e-3)" "unprognostic (2.80e-3)" "unprognostic (1.42e-1)" "unprognostic (6.26e-2)" "unprognostic (3.43e-2)" "unprognostic (5.21e-2)" "prognostic favorable (8.06e-6)" "unprognostic (6.11e-2)" "unprognostic (2.89e-1)" "unprognostic (3.43e-3)" "unprognostic (1.93e-1)" 122.0 15.9 21.0 20.0 24.7 136.2 83.7 19.2 27.5 65.6 22.3 29.6 24.8 69.5 23.3 39.2 42.3 44.2 62.2 20.8 24.0 147.2 164.9 75.0 13.7 34.7 26.8 49.6 20.2 19.5 19.1 22.2 24.6 25.6 21.2 19.0 32.4 36.9 240.5 57.9 32.2 38.3 18.6 26.8 53.2 12.3 25.3 30.7 73.8 26.4 16.8 50.4 44.4 28.7 138.6 9.7 22.3 7.5 44.8 43.9 219.8 239.5 122.6 88.5 96.7 50.8 25.3 61.1 71.4 42.0 206.6 85.3 3.0 219.6 164.5 44.9 23.6 75.7 24.0 51.8 365.9 22.5 7.5 76.7 117.8 107.7 577.7 41.5 61.0 15.2 165.6 109.9 104.5 4.8 7.2 27.3 29.8 19.3 96.3 16.4 177.2 67.9 44.2 110.5 102.7 17.1 51.9 15.2 158.3 79.7 2.6 23.2 61.6 85.7 111.6 89.3 165.7 267.3 54.9 106.8 37.8 11.1 86.3 23.6 5.7 48.4 6.3 2.8 5.3 2.3 4.4 5.3 2.6 1.5 1.2 2.0 8.2 6.5 2.0 4.1 18.6 8.7 21.0 24.7 19.2 27.5 20.8 24.0 34.7 26.8 24.6 18.6 25.3 28.7 402.5 64.1 19.0 6.8 51.2 858.9 2807.1 273.2 225.3 45.1 56.7 100.6 190.5 47.1 155.8 103.0 10.4 24.6 85.1 175.3 236.7 264.4 1.6 410.7 250.6 176.6 131.7 116.2 6.1 253.6 117.8 177.0 87.7 982.6 44.5 18.9 74.6 110.1 18.6 26.9 7.0 99.6 122.1 23.5 290.6 4.0 38.2 94.7 158.3 7.5 273.2 30.3 12.3 6.6 1.0 367.3 202.0 64.7 116.8 786.2 101.4 530.0 135.1 72.8 52.6 136.0 201.6 3.7 18.8 365.2 390.8 17.6 139.5 88.6 70.3 1740.4 GAR1 NOLA1 ENSG00000109534 "GAR1 ribonucleoprotein" Q9NY12 4 109815510-109824740 "Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059098 Supported Approved "Nucleoplasm,Nucleoli fibrillar center" NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli fibrillar center" "HPA059098: AB_2683904" "unprognostic (9.72e-2)" "unprognostic (6.94e-2)" "unprognostic (3.04e-2)" "unprognostic (4.47e-2)" "unprognostic (2.40e-1)" "unprognostic (1.24e-2)" "prognostic unfavorable (2.64e-5)" "unprognostic (1.01e-2)" "unprognostic (1.73e-1)" "unprognostic (4.17e-3)" "unprognostic (2.14e-2)" "unprognostic (2.45e-3)" "unprognostic (1.17e-1)" "unprognostic (5.11e-2)" "unprognostic (1.11e-1)" "unprognostic (6.49e-2)" "unprognostic (1.08e-3)" 14.7 16.4 10.0 13.5 10.1 31.7 15.9 9.8 13.0 12.3 10.1 16.0 11.3 13.7 11.4 23.0 13.3 6.4 12.7 10.0 10.3 20.1 16.5 9.6 13.5 10.1 10.1 15.5 14.7 9.3 11.8 11.5 10.3 12.2 15.2 7.1 13.2 8.0 12.2 23.2 13.2 11.7 9.9 15.5 12.9 15.1 10.3 13.8 10.7 6.6 16.0 16.3 13.5 10.6 45.7 65.5 34.3 49.7 19.3 26.8 34.1 47.1 24.1 35.3 30.1 100.6 60.2 103.5 27.5 38.9 39.5 22.2 68.8 47.7 66.5 31.2 68.3 57.7 57.1 113.1 46.6 150.8 35.2 27.0 49.5 48.6 37.6 27.9 44.5 48.1 146.8 34.6 50.0 121.7 78.5 115.4 59.5 78.4 68.7 58.0 57.2 41.2 55.3 79.3 51.2 55.7 26.3 80.6 46.2 29.5 25.1 48.4 39.3 38.5 51.1 27.2 61.4 42.0 70.7 132.2 26.3 69.7 43.2 7.5 4.0 2.9 6.1 6.7 6.5 8.4 5.9 6.2 6.3 7.9 6.7 6.2 0.7 7.3 6.3 6.8 6.8 2.6 10.0 10.1 9.8 13.0 10.0 10.3 10.1 10.1 10.3 9.9 10.3 10.6 25.2 3.2 17.0 4.6 29.0 57.9 40.9 42.7 27.3 11.9 36.3 37.2 13.8 14.3 33.1 16.5 14.6 69.9 23.4 18.5 25.4 49.2 1.3 54.0 39.9 30.9 18.6 62.1 6.6 53.8 65.8 24.7 30.1 36.9 19.0 38.1 18.2 19.6 35.8 5.0 6.3 40.7 10.2 13.3 17.2 4.3 22.1 16.0 17.8 5.6 16.1 39.2 17.5 5.5 7.4 49.5 22.7 18.8 24.7 68.5 14.5 40.4 35.6 9.3 6.6 35.2 27.7 45.0 38.3 40.2 60.0 87.8 24.8 44.6 46.1 40.6 GAS2L3 ENSG00000139354 "Growth arrest specific 2 like 3" Q86XJ1 12 100573683-100628288 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 33.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.3;myeloid DC: 1.5" "Group enriched" "Detected in many" 4 "dendritic cells: 1.5;monocytes: 1.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Region enriched" "Detected in some" 4 "spinal cord: 13.8" HPA048593 Approved NA Yes "Cluster 7: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "HPA048593: AB_2680455" "unprognostic (1.03e-1)" "unprognostic (5.13e-2)" "unprognostic (5.10e-2)" "unprognostic (2.70e-2)" "unprognostic (2.32e-2)" "unprognostic (1.46e-1)" "unprognostic (1.04e-7)" "unprognostic (2.79e-3)" "unprognostic (1.21e-1)" "unprognostic (1.40e-1)" "unprognostic (9.21e-2)" "unprognostic (3.04e-2)" "prognostic unfavorable (3.58e-7)" "unprognostic (1.34e-1)" "unprognostic (2.35e-1)" "unprognostic (3.60e-2)" "unprognostic (6.67e-2)" 1.8 0.8 0.1 1.6 1.4 5.6 0.8 0.1 0.7 1.2 0.5 3.3 2.7 0.7 0.4 1.6 0.3 4.8 1.5 0.5 0.1 1.3 1.0 2.5 1.3 0.5 0.5 1.1 0.5 0.2 0.2 3.5 0.5 0.3 3.8 0.4 0.5 1.1 0.8 3.4 2.7 1.6 0.3 1.4 1.4 4.0 1.4 0.9 0.6 1.2 1.2 1.6 0.5 1.1 35.4 14.0 18.6 14.8 5.7 7.3 6.2 16.2 15.3 21.3 23.8 10.4 9.5 0.6 4.8 12.8 20.8 11.8 12.0 5.9 31.0 10.0 9.1 0.0 12.2 7.0 1.9 0.0 8.0 2.9 0.6 12.8 36.1 10.1 20.2 0.0 2.2 0.0 17.7 10.4 0.0 0.2 5.9 6.5 16.7 2.4 32.5 0.8 9.2 9.6 8.4 8.1 17.0 11.7 22.2 6.5 21.3 1.9 13.6 13.6 14.3 12.2 17.8 7.4 9.3 0.0 5.3 5.6 39.3 0.3 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.1 0.1 1.4 0.1 0.7 0.5 0.1 0.5 0.5 0.5 0.3 1.4 1.1 3.6 0.0 0.0 1.0 0.2 3.4 0.4 0.5 2.8 0.2 2.0 2.2 2.0 11.5 0.2 0.0 0.0 9.9 0.4 9.8 0.0 2.7 4.5 3.6 5.5 5.6 3.6 6.9 2.5 0.7 4.5 2.2 11.2 7.4 1.3 7.2 2.5 1.4 13.9 0.0 5.9 14.2 0.0 8.0 11.1 0.5 0.6 14.7 7.2 4.7 1.5 2.2 0.0 2.5 0.3 0.3 8.2 0.7 0.3 0.6 2.6 3.4 1.0 0.1 0.0 4.8 2.7 16.0 2.3 4.7 3.7 33.9 1.0 6.8 8.3 0.6 GGCT "C7orf24, CRF21, GCTG, Ggc, MGC3077" ENSG00000006625 Gamma-glutamylcyclotransferase O75223 7 30496621-30504841 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 414.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020735, HPA029914" Approved NA Yes 2100000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA020735: AB_1845754, HPA029914: AB_10602321" "prognostic unfavorable (7.68e-4)" "unprognostic (2.66e-1)" "unprognostic (2.51e-2)" "unprognostic (2.62e-1)" "unprognostic (2.54e-3)" "unprognostic (5.80e-2)" "prognostic unfavorable (7.23e-4)" "unprognostic (1.33e-3)" "unprognostic (2.19e-2)" "unprognostic (6.42e-3)" "unprognostic (2.66e-3)" "unprognostic (1.68e-1)" "unprognostic (2.27e-2)" "unprognostic (1.19e-1)" "unprognostic (8.12e-3)" "unprognostic (2.00e-3)" "unprognostic (9.92e-2)" 58.6 25.6 18.1 28.4 20.5 22.4 44.8 16.9 24.4 19.2 19.5 38.6 31.3 17.3 105.2 51.7 24.4 25.9 13.0 20.0 18.3 31.9 35.6 16.6 27.8 18.0 18.1 15.5 23.3 43.5 15.9 34.8 17.3 24.9 39.4 10.7 33.4 15.9 16.9 56.5 26.6 21.2 17.3 16.0 22.7 12.1 19.7 21.9 19.3 20.8 32.2 33.1 31.2 17.8 194.0 50.0 79.4 107.7 32.6 58.8 92.5 64.6 25.1 60.5 72.4 66.6 66.1 123.7 42.0 24.3 68.9 238.8 84.1 67.8 78.6 24.0 93.1 87.7 104.6 88.6 42.6 150.1 65.4 57.6 53.4 63.4 81.0 20.9 62.1 58.7 126.8 69.4 48.6 108.6 91.4 202.1 115.6 198.3 79.5 90.1 91.9 123.8 59.5 174.0 100.3 101.2 58.0 355.9 73.5 102.8 228.7 140.7 37.7 39.6 75.6 75.6 128.6 50.8 129.2 96.7 30.9 201.4 75.9 10.4 19.9 7.0 14.1 20.4 19.9 22.7 18.8 18.4 34.2 17.2 17.8 17.4 1.1 25.0 12.2 30.0 26.1 17.2 18.1 20.5 16.9 24.4 20.0 18.3 18.0 18.1 17.3 17.3 19.7 17.8 37.9 16.0 39.4 10.1 25.1 77.0 50.1 96.0 60.3 23.4 107.0 109.5 51.6 24.3 67.0 44.1 4.2 414.7 21.8 56.9 123.3 99.8 29.2 129.6 40.4 46.3 28.3 53.0 26.0 80.1 167.7 41.4 44.9 103.8 27.3 53.5 33.5 51.4 129.8 33.7 10.1 90.1 67.1 44.5 57.4 10.0 24.8 42.8 62.2 12.2 36.2 32.2 24.7 8.5 8.9 60.1 50.6 39.1 33.4 68.8 60.6 188.4 69.4 15.1 26.3 25.2 45.1 63.3 46.7 147.0 74.7 135.6 26.7 67.7 138.0 69.6 GINS2 "Pfs2, PSF2" ENSG00000131153 "GINS complex subunit 2" Q9Y248 16 85676198-85690073 "Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 163.5;Spermatogonia: 148.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 8.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-698: 271.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA057285 Uncertain Approved Nucleoplasm No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA057285: AB_2683398" "unprognostic (3.22e-2)" "unprognostic (1.13e-3)" "unprognostic (2.04e-3)" "unprognostic (2.09e-1)" "unprognostic (2.64e-1)" "unprognostic (1.30e-1)" "unprognostic (2.45e-3)" "unprognostic (2.58e-2)" "unprognostic (1.67e-2)" "unprognostic (2.52e-3)" "unprognostic (2.19e-2)" "unprognostic (5.82e-3)" "unprognostic (5.70e-3)" "unprognostic (4.54e-2)" "unprognostic (6.30e-2)" "unprognostic (5.44e-3)" "unprognostic (1.60e-1)" 1.0 0.9 3.0 5.4 2.8 14.7 3.7 3.0 3.7 1.7 2.2 6.4 4.6 1.6 1.3 4.7 1.1 0.4 0.6 4.5 2.2 0.7 3.0 0.8 9.0 2.3 2.4 1.4 0.9 2.6 0.8 3.0 2.3 1.5 7.0 11.1 1.3 0.8 2.7 3.2 5.3 1.6 2.3 3.0 2.2 9.6 2.3 10.2 1.8 1.0 11.0 1.4 2.1 2.6 50.7 36.2 69.0 28.9 2.0 6.7 18.3 33.8 13.7 49.8 30.5 48.2 32.9 60.0 18.1 12.0 26.0 38.0 73.7 28.1 47.9 20.8 63.9 29.2 25.7 54.6 0.3 20.6 15.6 1.8 3.4 30.0 11.5 6.1 21.6 47.5 82.4 13.8 28.9 107.1 72.7 77.8 38.8 45.0 27.3 100.7 41.5 33.1 16.4 20.9 94.2 30.0 49.4 10.0 10.0 27.3 100.0 28.2 12.8 32.1 42.5 30.6 39.5 25.6 48.3 271.9 18.7 43.4 37.2 0.7 0.2 1.1 1.0 1.0 0.1 1.0 3.3 2.3 1.3 0.7 1.6 1.1 0.9 3.2 2.8 0.8 8.5 1.7 3.0 2.8 3.0 3.7 4.5 2.2 2.3 2.4 2.3 2.3 2.3 2.6 0.6 3.2 0.0 0.7 8.5 9.2 7.4 9.5 4.0 20.3 13.1 18.5 1.0 0.0 3.8 3.7 2.1 35.3 3.1 11.9 3.9 8.2 9.8 1.5 3.3 2.4 3.0 43.3 0.5 1.5 31.8 7.2 5.6 2.7 1.3 21.6 0.0 2.1 23.8 8.4 0.4 14.9 4.1 1.3 6.6 29.4 1.2 3.3 0.0 0.0 1.1 5.6 0.0 1.0 0.6 2.0 4.5 1.9 43.1 2.6 2.4 0.7 1.7 7.5 19.7 4.2 7.9 163.5 148.4 13.8 3.8 12.7 4.2 2.2 33.6 7.4 GOLGA8A "CFAP286, FAP286, GM88, GOLGIN-67" ENSG00000175265 "Golgin A8 family member A" A7E2F4 15 34379068-34437466 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 211.5;Oligodendrocyte precursor cells: 146.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 48.0;HeLa: 80.1" HPA051808 Approved Approved "Golgi apparatus,Cytosol" NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" Cytosol "HPA051808: AB_2681620" "unprognostic (4.80e-2)" "unprognostic (1.26e-2)" "unprognostic (4.54e-1)" "unprognostic (1.32e-1)" "unprognostic (2.42e-2)" "unprognostic (2.10e-2)" "unprognostic (8.11e-3)" "prognostic favorable (7.58e-4)" "unprognostic (2.74e-2)" "unprognostic (4.37e-1)" "unprognostic (2.63e-3)" "unprognostic (2.25e-2)" "prognostic unfavorable (2.16e-6)" "unprognostic (2.23e-1)" "unprognostic (1.39e-1)" "unprognostic (2.26e-1)" "prognostic favorable (5.68e-6)" 24.5 18.6 16.1 10.4 11.7 7.9 32.4 18.5 21.4 56.3 11.0 32.7 10.5 31.6 31.8 31.2 37.6 7.3 23.6 13.1 10.0 33.2 6.8 22.4 14.0 17.8 8.8 62.5 22.9 6.3 22.8 2.2 11.9 37.8 2.2 26.4 26.8 10.2 7.6 36.8 38.2 3.2 7.0 48.1 30.3 40.0 12.8 1.2 56.8 1.0 2.1 33.0 40.2 12.2 2.4 13.4 3.7 12.5 0.1 0.0 2.8 20.3 0.1 3.4 1.5 23.3 0.0 0.1 3.6 2.4 6.9 21.7 9.5 6.8 5.3 20.1 7.6 48.0 80.1 15.0 1.3 18.4 12.6 0.0 19.5 2.3 0.5 2.3 0.3 7.0 46.0 40.0 9.2 4.3 4.7 34.6 6.9 6.4 7.2 19.6 11.2 16.2 7.7 13.8 17.1 8.2 13.6 9.2 2.2 0.1 3.6 11.4 10.5 15.7 3.5 0.0 3.6 37.5 13.4 5.5 4.7 38.9 3.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 16.1 11.7 18.5 21.4 13.1 10.0 17.8 8.8 11.9 7.0 12.8 12.2 37.3 211.5 71.6 82.9 16.1 26.1 10.9 13.4 7.4 95.3 36.1 41.9 35.0 5.7 127.6 1.8 100.1 2.9 21.1 6.5 0.0 4.2 37.5 17.6 83.9 18.4 16.1 2.5 114.4 2.6 5.0 17.4 13.7 52.3 13.9 39.3 14.6 1.5 2.4 84.1 91.8 11.9 14.2 6.8 20.1 8.4 31.4 8.5 23.2 38.4 1.7 14.8 6.2 146.8 62.5 4.7 6.9 21.1 19.3 8.5 6.6 0.9 52.0 117.6 0.0 26.7 22.4 33.0 23.5 7.8 21.6 3.3 32.9 39.9 11.7 9.4 GOLGA8B ENSG00000215252 "Golgin A8 family member B" A8MQT2 15 34525207-34588503 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "pancreas: 228.4" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 192.3;Excitatory neurons: 133.4;Inhibitory neurons: 126.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 14.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 20.4;Hep G2: 16.2;NB-4: 24.5" HPA051808 Approved Approved "Golgi apparatus,Cytosol" NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 25: Pancreas - Digestion" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" Cytosol "HPA051808: AB_2681620" "unprognostic (2.12e-3)" "unprognostic (2.06e-1)" "unprognostic (1.85e-1)" "unprognostic (2.89e-1)" "unprognostic (2.43e-1)" "unprognostic (4.06e-2)" "unprognostic (7.90e-3)" "unprognostic (9.67e-3)" "unprognostic (9.02e-2)" "unprognostic (1.06e-1)" "unprognostic (1.60e-3)" "unprognostic (1.49e-2)" "prognostic unfavorable (9.38e-6)" "unprognostic (2.14e-1)" "unprognostic (5.31e-3)" "unprognostic (2.31e-1)" "prognostic favorable (5.79e-4)" 16.5 28.8 10.9 7.2 11.0 18.4 20.8 13.8 15.0 28.7 10.8 18.6 0.9 16.8 11.9 10.0 27.9 6.9 15.5 11.0 11.1 41.1 41.8 23.8 19.6 11.2 10.9 55.6 228.4 0.7 60.6 3.0 10.9 37.8 1.4 8.0 18.1 10.6 10.1 13.4 25.2 2.0 10.9 38.5 28.7 43.2 11.1 2.8 113.8 1.3 7.4 19.7 13.4 11.2 2.6 2.8 0.3 5.3 2.8 5.4 7.3 2.3 0.7 2.5 4.0 2.8 3.5 0.0 4.7 2.5 0.3 2.1 0.9 2.4 1.9 3.6 8.4 0.4 20.4 16.2 3.9 2.3 2.5 7.8 3.3 1.5 4.5 2.7 2.6 4.0 0.9 0.2 2.3 1.2 1.2 24.5 3.2 5.0 4.6 0.1 0.0 0.4 2.2 4.9 3.8 5.8 1.3 0.4 3.2 3.9 2.2 4.8 0.0 3.7 8.8 1.1 4.0 1.8 1.7 3.9 1.2 1.2 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 11.0 13.8 15.0 11.0 11.1 11.2 10.9 10.9 10.9 11.1 11.2 19.0 192.3 66.5 95.0 34.8 21.9 8.8 10.9 33.0 53.6 30.9 34.3 37.4 20.0 74.7 31.3 73.0 7.6 30.6 2.8 1.9 9.2 53.8 17.3 27.1 11.0 7.2 13.0 133.4 13.0 5.4 12.7 20.4 24.5 9.5 36.4 11.0 28.7 1.5 45.4 126.1 10.1 12.2 6.6 9.9 10.8 39.4 5.0 21.4 12.2 6.4 9.3 32.0 112.1 24.2 16.8 4.9 37.6 45.1 7.6 7.1 5.8 39.9 67.8 13.1 13.5 13.8 48.9 28.4 10.0 14.8 2.9 49.8 22.0 9.4 6.6 GOT1 AST1 ENSG00000120053 "Glutamic-oxaloacetic transaminase 1" P17174 10 99396870-99430624 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Amino-acid biosynthesis" "Aminotransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "heart muscle: 511.1;liver: 369.5;skeletal muscle: 489.9;tongue: 1011.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 449.0;Distal tubular cells: 240.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064532, HPA072629" Enhanced Supported Nucleoplasm,Cytosol NA Yes 100000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "HPA064532: AB_2685279, HPA072629: AB_2686540" "unprognostic (6.40e-2)" "prognostic favorable (6.23e-4)" "unprognostic (5.99e-2)" "unprognostic (2.84e-2)" "unprognostic (2.82e-1)" "unprognostic (2.96e-2)" "unprognostic (5.25e-2)" "unprognostic (1.08e-3)" "unprognostic (6.67e-2)" "unprognostic (1.45e-1)" "unprognostic (1.79e-2)" "unprognostic (1.79e-1)" "prognostic favorable (3.72e-13)" "unprognostic (1.93e-2)" "unprognostic (4.23e-1)" "unprognostic (6.85e-2)" "unprognostic (1.00e-1)" 14.7 54.9 67.8 14.7 71.1 8.0 22.7 70.3 119.1 53.1 82.6 50.9 62.0 13.1 25.9 42.7 17.9 49.0 511.1 70.0 77.6 143.1 369.5 15.5 14.1 83.5 55.0 18.1 34.0 142.4 22.5 14.4 83.7 22.7 59.2 106.2 48.6 27.4 489.9 23.9 45.8 21.4 48.4 16.9 58.9 33.6 69.1 17.7 47.7 1011.6 30.3 22.3 21.0 70.1 73.7 40.3 46.0 114.4 35.1 30.7 127.1 58.9 108.7 101.8 109.8 89.9 56.4 71.9 20.4 50.2 89.2 88.6 107.1 78.9 105.8 25.7 46.7 28.1 46.7 114.3 184.9 77.9 44.0 47.3 82.5 86.9 228.4 69.5 49.5 48.6 71.1 106.2 65.4 64.9 42.5 56.5 29.2 118.7 56.1 45.5 44.4 72.8 173.7 37.5 19.6 28.7 44.8 59.3 222.6 66.8 115.7 27.1 23.3 25.4 56.3 28.0 68.7 76.8 99.7 74.3 65.4 40.8 34.1 4.0 8.7 6.8 19.7 25.8 18.4 17.6 21.5 20.7 21.9 21.2 15.6 22.7 0.8 20.5 31.5 36.4 27.6 15.6 67.8 71.1 70.3 119.1 70.0 77.6 83.5 55.0 83.7 48.4 69.1 70.1 10.3 16.0 16.2 26.1 38.8 11.9 41.8 82.7 24.5 95.6 18.8 21.2 449.0 72.9 34.4 73.5 62.6 35.9 10.7 62.1 240.7 51.9 166.7 17.8 9.3 16.7 19.7 39.5 47.4 30.8 18.1 23.5 76.9 21.5 31.8 20.2 17.2 191.8 31.6 75.7 63.3 45.3 54.9 12.4 6.9 24.1 11.1 13.0 49.8 13.1 10.5 36.6 6.2 21.1 37.2 27.6 34.4 14.3 22.4 13.1 97.0 163.3 27.9 76.5 13.1 15.2 20.5 116.7 10.4 40.9 10.4 55.1 14.6 47.0 66.4 42.3 GPANK1 "ANKRD59, BAT4, D6S54E, G5, GPATCH10" ENSG00000204438 "G-patch domain and ankyrin repeats 1" O95872 6 31661228-31666283 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 180.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006301 Approved Approved "Endoplasmic reticulum" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum" "HPA006301: AB_1078267" "unprognostic (2.03e-1)" "unprognostic (2.84e-2)" "unprognostic (1.56e-1)" "unprognostic (1.05e-1)" "unprognostic (4.26e-2)" "unprognostic (1.20e-1)" "unprognostic (1.77e-2)" "unprognostic (5.72e-2)" "unprognostic (1.10e-1)" "unprognostic (8.81e-2)" "prognostic favorable (5.89e-4)" "unprognostic (2.29e-1)" "unprognostic (2.46e-2)" "unprognostic (2.00e-1)" "unprognostic (1.86e-1)" "unprognostic (5.40e-2)" "unprognostic (1.51e-1)" 14.5 11.8 1.5 2.7 1.9 3.9 14.7 3.6 2.8 14.9 1.4 15.9 1.6 15.9 2.5 11.4 14.9 2.1 21.5 1.5 1.8 14.7 16.0 13.2 3.8 2.0 1.7 17.3 15.1 3.3 13.5 1.8 2.2 14.0 2.4 2.3 13.8 2.0 28.4 15.8 15.6 1.1 1.4 16.7 15.4 36.4 1.8 6.7 12.8 2.8 2.3 15.0 13.3 2.6 3.3 3.3 1.7 5.6 8.3 6.6 4.4 3.2 5.2 3.1 4.2 0.2 4.8 10.8 5.2 3.4 4.2 3.9 0.0 8.1 2.3 6.4 5.6 11.3 0.0 3.7 5.7 3.7 4.3 3.2 4.3 10.4 6.9 6.1 3.8 10.9 3.0 8.8 4.2 2.6 13.1 4.4 0.0 5.1 1.2 5.4 7.5 7.9 5.1 2.6 12.6 8.4 4.3 1.9 5.4 4.6 5.1 9.2 4.8 7.3 7.0 0.5 0.0 6.5 10.8 4.1 8.6 7.9 4.2 11.8 3.1 9.9 4.1 2.5 4.1 2.0 3.2 2.5 3.1 2.9 3.7 3.3 9.5 4.5 2.6 3.8 4.6 2.7 1.5 1.9 3.6 2.8 1.5 1.8 2.0 1.7 2.2 1.4 1.8 2.6 22.6 38.5 21.7 5.9 30.5 25.0 24.2 27.6 23.3 29.1 25.0 23.4 35.9 30.0 21.6 18.4 35.5 30.1 28.3 26.4 45.0 31.6 55.4 21.9 21.4 29.1 27.1 33.0 3.2 23.6 39.7 23.8 13.3 22.9 35.4 21.9 27.8 30.3 27.7 11.8 3.5 29.9 22.4 27.0 18.5 51.5 34.5 21.0 19.6 3.7 43.5 37.8 47.4 5.0 7.3 21.9 43.3 24.8 29.2 32.3 90.5 74.5 20.1 47.3 19.7 21.6 29.7 180.8 87.2 16.2 34.2 47.1 26.9 17.3 26.9 19.9 GPRC5A "PEIG-1, RAI3, RAIG1, TIG1" ENSG00000013588 "G protein-coupled receptor class C group 5 member A" Q8NFJ5 12 12891559-12917937 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 201.9;urinary bladder: 130.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 939.1;Club cells: 357.8;Distal enterocytes: 477.9;Pancreatic endocrine cells: 600.7;Paneth cells: 359.8;Urothelial cells: 1252.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 355.6;A549: 285.7;CAPAN-2: 1347.4;HaCaT: 351.2;SiHa: 492.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA007928, HPA046526" Enhanced Enhanced "Vesicles,Plasma membrane" NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Plasma membrane" "HPA007928: AB_1849318, HPA046526: AB_2679685" "unprognostic (4.79e-2)" "unprognostic (8.35e-2)" "unprognostic (4.21e-2)" "unprognostic (1.64e-1)" "unprognostic (4.65e-3)" "unprognostic (1.73e-1)" "unprognostic (2.38e-2)" "unprognostic (1.89e-2)" "unprognostic (3.48e-1)" "unprognostic (8.69e-3)" "prognostic unfavorable (4.63e-6)" "unprognostic (3.81e-1)" "prognostic unfavorable (9.02e-5)" "unprognostic (9.30e-2)" "unprognostic (4.34e-1)" "unprognostic (1.62e-2)" "unprognostic (2.49e-1)" 31.5 3.7 1.2 11.5 0.9 1.8 9.6 1.0 1.4 35.4 3.4 56.4 18.7 8.9 0.4 23.0 9.8 24.9 18.9 1.8 0.8 9.0 1.8 201.9 0.2 2.7 4.5 21.4 2.7 0.9 2.5 13.5 1.0 10.2 48.4 1.6 23.5 1.3 0.7 5.8 20.9 5.1 0.5 0.4 33.6 1.5 2.1 0.3 55.5 0.6 4.4 130.8 30.6 1.8 355.6 285.7 0.1 1.3 3.4 1.5 18.4 105.2 39.5 66.2 49.4 49.1 1347.4 0.1 8.6 83.3 67.2 351.2 1.0 50.1 101.7 0.4 4.3 0.2 105.4 2.2 23.8 0.1 0.3 1.8 66.5 27.5 6.7 82.3 40.9 0.0 0.5 0.3 2.9 251.7 0.2 0.3 1.6 130.0 43.5 0.2 6.7 0.3 133.6 69.6 0.5 0.6 492.0 36.8 15.9 52.3 10.9 1.0 4.0 2.6 83.9 156.1 4.3 0.2 0.3 0.3 34.6 0.3 2.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 1.2 0.9 1.0 1.4 1.8 0.8 2.7 4.5 1.0 0.5 2.1 1.8 10.0 939.1 200.2 0.0 1.0 12.5 329.6 202.8 4.6 0.1 80.6 41.7 1.9 11.5 357.8 46.0 0.0 3.8 1.5 477.9 0.0 46.9 0.1 91.8 54.1 15.8 8.3 0.0 0.2 72.1 11.7 108.5 176.9 288.1 10.1 0.2 8.6 0.2 1.6 0.0 0.4 43.5 61.1 0.3 18.0 0.4 13.4 9.6 51.6 0.0 0.6 3.5 0.0 0.0 0.1 600.7 359.8 10.1 0.5 320.1 114.0 0.2 86.3 0.4 0.0 23.0 38.8 1.5 0.3 22.7 9.1 1.1 4.9 0.7 110.4 1252.7 GPRC5C RAIG-3 ENSG00000170412 "G protein-coupled receptor class C group 5 member C" Q9NQ84 17 74424851-74451653 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 192.7;stomach 1: 230.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 211.3;Gastric mucus-secreting cells: 143.2;Hepatocytes: 183.6;Paneth cells: 153.8;Sertoli cells: 144.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 7.9" "Group enriched" "Detected in many" 9 "dendritic cells: 7.9;monocytes: 3.7" "Cell line enhanced" "Detected in many" "Hep G2: 82.4;HMC-1: 146.7;PC-3: 80.8;RPTEC TERT1: 172.1;RT4: 89.9;T-47d: 108.0" "Region enriched" "Detected in all" 9 "cerebellum: 42.5" "Low region specificity" "Detected in all" HPA029776 Enhanced Uncertain "Nucleoplasm,Centriolar satellite,Cytosol" NA Yes 15000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" "Centriolar satellite" "Nucleoplasm, Cytosol" "HPA029776: AB_10602324" "unprognostic (1.48e-1)" "unprognostic (3.35e-1)" "unprognostic (6.01e-2)" "unprognostic (2.37e-3)" "unprognostic (1.80e-2)" "unprognostic (1.09e-2)" "unprognostic (4.40e-2)" "unprognostic (1.57e-1)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" "unprognostic (9.61e-3)" "unprognostic (1.05e-1)" "prognostic favorable (1.58e-5)" "unprognostic (7.58e-2)" "unprognostic (3.70e-2)" "unprognostic (2.75e-2)" "unprognostic (1.54e-3)" 16.1 19.3 17.4 3.1 18.4 0.4 20.1 48.9 18.1 42.0 28.0 38.7 25.0 17.1 10.2 12.2 30.0 21.3 33.7 14.8 16.9 135.7 192.7 23.0 2.1 18.1 18.7 38.2 136.1 28.2 14.8 11.9 18.6 45.6 14.6 1.5 37.4 24.3 110.1 43.9 30.3 4.0 16.6 22.3 230.3 4.0 17.0 4.4 74.8 33.9 3.0 30.8 20.9 15.7 17.3 61.6 3.8 5.5 0.0 0.0 0.2 0.3 0.0 0.0 0.0 66.4 73.0 0.0 45.0 0.3 18.5 52.9 7.7 1.0 0.1 0.2 10.7 0.0 4.0 82.4 15.8 0.0 146.7 1.3 26.7 0.0 0.0 69.2 0.0 0.1 4.8 1.2 0.0 18.0 0.7 17.2 9.2 79.5 80.8 0.2 0.1 2.8 172.1 89.9 27.5 2.5 3.7 5.9 0.1 33.1 108.0 4.6 0.0 0.0 5.5 0.1 0.1 0.1 0.4 0.2 6.5 2.5 0.4 0.0 1.1 0.1 0.0 2.5 0.0 0.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 3.7 7.9 0.0 0.3 17.4 18.4 48.9 18.1 14.8 16.9 18.1 18.7 18.6 16.6 17.0 15.7 11.2 3.2 57.7 13.4 1.4 13.6 39.2 79.6 26.7 0.8 27.3 19.4 211.3 67.2 76.2 136.1 0.0 0.8 11.8 74.9 29.4 65.5 0.1 62.5 6.6 20.9 45.5 5.3 0.1 68.1 20.3 11.3 143.2 74.9 10.2 0.1 48.2 183.6 12.3 5.0 0.5 50.8 69.2 16.3 4.6 1.7 18.0 6.3 3.6 2.8 4.1 15.9 0.0 5.0 0.2 41.2 153.8 22.2 1.2 44.6 61.0 73.5 45.4 1.5 144.7 4.7 64.0 0.5 5.0 14.8 11.2 25.3 2.4 1.5 48.5 63.1 GPSM2 "DFNB82, LGN, Pins" ENSG00000121957 "G protein signaling modulator 2" P81274 1 108875350-108934545 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis, Transport" Deafness "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 46.9;tongue: 54.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 133.5;Oligodendrocyte precursor cells: 134.7;Oligodendrocytes: 127.4;Syncytiotrophoblasts: 89.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 3.2;T-reg: 1.8" "Group enriched" "Detected in many" 5 "granulocytes: 3.2;T-cells: 1.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007327, HPA008408, CAB018962" Uncertain Supported Cytosol NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "CAB018962: , HPA007327: AB_1849941, HPA008408: AB_1849939" "unprognostic (1.97e-1)" "unprognostic (6.80e-2)" "prognostic favorable (7.86e-5)" "unprognostic (1.37e-3)" "unprognostic (3.18e-2)" "unprognostic (1.97e-2)" "unprognostic (8.57e-6)" "unprognostic (7.12e-2)" "unprognostic (2.76e-2)" "unprognostic (3.92e-2)" "prognostic unfavorable (5.89e-4)" "unprognostic (7.55e-3)" "prognostic unfavorable (3.02e-4)" "unprognostic (6.27e-3)" "unprognostic (1.00e-1)" "unprognostic (5.14e-3)" "unprognostic (6.00e-2)" 5.3 3.5 27.3 4.4 39.5 14.4 7.5 33.8 25.2 12.6 10.8 15.3 9.1 6.8 2.6 34.1 4.2 2.6 4.3 23.3 29.5 2.3 2.9 9.0 6.4 33.9 36.3 3.3 3.6 9.7 3.1 7.7 33.9 5.9 15.2 8.6 10.1 4.7 10.7 37.7 11.5 10.5 32.1 2.7 5.1 11.5 34.1 18.4 3.2 54.4 13.2 6.0 17.7 46.9 135.6 16.2 36.8 27.7 36.4 20.2 30.0 24.2 61.4 29.9 45.4 16.0 31.7 30.5 6.7 33.4 21.0 28.3 25.3 59.1 39.6 30.7 15.8 19.8 34.7 16.5 4.8 28.6 18.5 4.1 113.9 29.4 129.8 9.4 26.9 19.5 14.9 42.3 58.4 37.8 26.1 12.2 8.7 52.1 29.4 20.1 66.7 6.6 24.3 18.6 30.4 26.9 37.0 69.2 26.9 10.3 27.6 24.3 18.0 21.7 36.7 64.8 48.5 18.4 20.9 28.6 34.3 47.4 108.9 0.1 0.3 3.2 0.2 0.3 0.1 0.2 0.2 0.2 0.3 0.4 0.4 0.3 0.3 0.1 0.1 0.1 1.8 0.1 27.3 39.5 33.8 25.2 23.3 29.5 33.9 36.3 33.9 32.1 34.1 46.9 4.6 16.0 3.3 63.0 5.7 62.7 18.8 12.9 47.3 47.7 3.0 3.7 2.5 2.8 12.5 7.3 133.5 46.3 6.7 10.8 11.7 2.5 54.0 5.2 20.6 5.1 9.1 33.9 11.7 1.9 47.7 19.5 8.6 9.2 2.5 14.4 2.9 1.6 9.0 43.7 24.0 14.1 10.2 5.3 11.3 21.3 18.6 4.9 26.6 3.7 5.3 8.0 2.1 134.7 127.4 4.8 7.8 5.3 5.3 5.6 8.4 0.9 9.0 48.1 0.0 43.6 6.9 20.6 28.9 24.0 40.6 89.2 7.1 10.0 18.7 15.5 GRINA "HNRGW, LFG1, NMDARA1, TMBIM3" ENSG00000178719 "Glutamate ionotropic receptor NMDA type subunit associated protein 1" Q7Z429 8 143990056-143993415 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 432.6;monocytes: 355.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036980, HPA036981" Approved Approved "Nucleoli fibrillar center,Cytosol" NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 3: Monocytes - Immune response regulation" "Nucleoli fibrillar center" Cytosol "HPA036980: AB_10696791, HPA036981: AB_10962980" "unprognostic (2.73e-3)" "unprognostic (2.18e-3)" "unprognostic (1.79e-2)" "unprognostic (1.12e-1)" "unprognostic (7.01e-3)" "unprognostic (3.72e-2)" "unprognostic (1.69e-1)" "unprognostic (1.35e-2)" "unprognostic (2.32e-1)" "unprognostic (6.70e-2)" "unprognostic (8.19e-2)" "unprognostic (3.13e-3)" "unprognostic (1.01e-3)" "unprognostic (1.55e-1)" "unprognostic (9.43e-2)" "unprognostic (6.75e-2)" "unprognostic (5.72e-2)" 273.1 218.3 154.1 109.0 147.4 215.1 236.4 143.9 226.4 178.9 99.4 144.9 72.1 137.8 79.7 134.2 149.0 74.5 154.8 158.9 149.8 200.8 447.1 233.9 77.7 151.6 155.6 152.7 97.2 144.4 127.7 86.2 160.5 176.0 33.2 180.7 116.7 181.7 145.4 167.1 138.1 75.1 152.1 311.3 104.6 269.4 163.1 58.5 187.4 57.4 55.2 162.1 139.3 140.2 79.3 155.9 76.4 129.5 392.6 196.9 114.5 112.5 258.9 184.4 168.7 95.5 64.3 57.9 120.2 249.7 128.6 69.8 136.8 162.3 75.5 83.1 95.9 60.2 85.9 114.5 412.0 12.7 90.7 254.2 441.0 132.7 193.3 194.5 90.1 23.9 56.1 76.8 160.7 489.5 34.7 32.6 53.4 75.8 231.2 45.4 39.9 111.4 93.2 229.1 52.3 84.8 163.5 177.9 225.8 104.1 342.2 77.6 91.8 115.4 127.1 158.0 82.1 124.3 78.3 44.6 147.4 79.0 67.6 1.8 32.0 9.7 2.5 36.4 3.5 8.3 2.5 2.9 13.3 7.1 4.5 4.1 18.6 3.3 36.1 22.9 2.3 16.0 154.1 147.4 143.9 226.4 158.9 149.8 151.6 155.6 160.5 152.1 163.1 140.2 54.5 19.2 52.7 35.3 45.4 37.2 32.5 58.7 121.3 91.1 62.7 79.4 23.2 45.8 27.9 53.3 79.2 137.2 22.6 29.1 23.5 75.0 273.8 36.8 56.1 47.7 42.1 60.0 21.3 69.1 55.8 67.7 16.8 36.1 16.4 76.2 51.4 194.5 178.4 33.7 26.6 24.3 42.7 225.1 86.7 432.6 61.5 184.3 37.4 22.5 355.1 89.9 6.2 12.5 9.3 66.0 54.5 67.7 44.4 46.7 72.9 73.6 29.4 95.8 46.0 32.4 45.6 96.0 16.9 83.2 36.9 264.2 20.8 38.7 31.4 25.5 GTPBP2 ENSG00000172432 "GTP binding protein 2" Q9BX10 6 43605316-43629264 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 5.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 5.4" "Cell line enhanced" "Detected in all" "hTERT-HME1: 181.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031418, HPA031419" Approved Approved Vesicles NA Yes "Cluster 34: Basophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA031418: AB_2673872, HPA031419: AB_10600709" "unprognostic (1.35e-1)" "unprognostic (1.01e-1)" "unprognostic (8.94e-2)" "unprognostic (1.08e-3)" "unprognostic (2.56e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (1.08e-6)" "unprognostic (4.71e-2)" "unprognostic (2.58e-3)" "unprognostic (6.47e-2)" "unprognostic (8.31e-2)" "unprognostic (6.15e-3)" "prognostic unfavorable (1.44e-15)" "unprognostic (1.13e-1)" "unprognostic (3.36e-1)" "unprognostic (1.06e-1)" "unprognostic (2.89e-3)" 38.5 29.8 14.5 15.3 15.3 28.7 37.4 16.5 17.9 39.5 16.0 34.0 19.9 26.8 15.5 61.3 25.1 12.5 35.4 14.4 15.0 36.1 33.3 46.7 16.9 17.5 16.7 29.0 40.0 24.1 40.0 18.0 15.6 31.5 17.0 18.9 42.6 11.6 31.6 26.5 34.7 15.4 14.3 44.5 35.9 27.2 17.0 16.8 44.2 10.4 17.0 33.9 40.4 16.2 59.2 10.9 37.7 24.0 28.3 30.6 45.6 56.3 55.2 52.6 70.1 12.0 19.9 18.8 23.5 26.9 53.8 31.6 9.8 14.5 45.6 60.9 31.6 44.1 33.0 13.9 126.0 35.6 50.1 35.1 160.5 72.5 181.4 35.1 20.5 25.7 77.1 107.8 26.2 13.9 23.4 45.1 10.6 41.2 14.8 19.4 29.5 17.5 24.0 25.8 33.1 32.4 19.5 14.0 72.5 19.0 30.3 37.3 34.8 27.2 33.2 20.5 38.3 70.8 38.2 26.7 45.4 26.0 27.5 5.4 0.8 2.1 1.2 0.7 0.9 0.6 0.2 1.1 0.4 1.0 0.7 1.0 1.3 0.6 0.9 1.1 0.6 1.2 14.5 15.3 16.5 17.9 14.4 15.0 17.5 16.7 15.6 14.3 17.0 16.2 19.6 3.2 5.5 6.8 5.1 5.2 2.3 4.3 1.2 5.9 7.5 5.0 11.4 5.7 5.7 1.8 8.4 2.8 5.3 24.0 0.0 10.1 17.0 8.5 8.2 9.7 1.2 14.3 7.2 10.1 9.8 6.8 11.7 13.3 1.3 5.7 6.8 5.5 8.2 1.7 6.3 8.8 2.0 12.6 6.5 47.6 5.3 16.0 7.2 5.6 10.1 3.4 1.0 5.5 9.1 20.7 13.4 4.1 2.4 5.8 6.8 1.8 4.1 9.2 13.1 5.3 7.8 7.1 8.1 4.4 5.3 2.5 3.8 4.7 6.0 12.6 GTSE1 "B99, GTSE-1" ENSG00000075218 "G2 and S-phase expressed 1" Q9NYZ3 22 46296870-46330810 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.2;lymphoid tissue: 19.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 52.2;Extravillous trophoblasts: 31.2;Granulosa cells: 27.1;Spermatocytes: 73.6;Spermatogonia: 27.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA029457 Approved "Plasma membrane,Centrosome" Yes Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "Plasma membrane" "HPA029457: " "unprognostic (1.97e-1)" "unprognostic (3.07e-2)" "unprognostic (1.71e-3)" "unprognostic (2.59e-1)" "unprognostic (7.16e-2)" "unprognostic (2.40e-2)" "prognostic unfavorable (1.90e-10)" "prognostic unfavorable (4.66e-4)" "unprognostic (1.09e-1)" "unprognostic (8.37e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (3.49e-3)" "unprognostic (0.00e+0)" "unprognostic (6.52e-3)" "unprognostic (3.25e-1)" "unprognostic (1.14e-1)" "unprognostic (4.85e-2)" 0.6 0.6 0.2 5.1 0.2 11.2 0.5 0.5 0.3 0.7 0.2 2.4 4.1 0.8 0.0 3.6 0.2 0.5 0.3 0.2 0.3 0.3 0.4 0.6 9.2 0.4 0.3 0.2 0.2 0.1 0.1 2.6 0.4 0.2 2.6 0.1 0.7 0.1 0.1 2.5 2.9 1.2 0.1 2.4 1.9 7.2 0.5 19.6 0.2 0.2 8.7 1.0 1.2 0.4 59.5 27.6 53.2 42.2 1.1 3.0 25.5 50.3 23.5 71.7 58.8 29.3 21.9 55.7 13.0 19.4 32.8 30.3 48.0 12.7 45.7 33.7 52.0 37.4 38.9 22.8 0.1 67.5 43.8 0.6 1.0 30.9 15.6 7.5 31.2 39.7 29.0 67.8 43.4 33.1 60.9 33.0 37.2 24.2 30.7 59.6 59.7 36.3 11.7 10.7 27.5 37.5 48.1 30.7 21.5 23.8 26.2 25.8 25.1 40.6 75.8 33.4 53.7 38.6 19.7 56.3 25.8 32.2 60.5 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.5 0.3 0.0 0.4 0.3 0.2 0.2 0.2 0.5 0.3 0.2 0.3 0.4 0.3 0.4 0.1 0.5 0.4 1.1 0.0 0.0 0.7 7.0 2.8 1.1 2.1 0.6 0.7 2.8 3.4 1.6 0.0 0.5 0.0 0.0 19.2 6.8 7.6 0.0 0.9 5.6 2.1 4.7 3.9 1.2 52.2 0.3 0.2 31.2 5.1 16.8 4.3 0.0 27.1 6.4 1.2 19.9 0.0 0.5 9.4 2.0 7.5 4.0 3.9 0.3 4.7 0.0 0.0 0.1 0.4 0.0 0.5 0.1 0.8 0.2 0.7 19.1 1.8 0.5 0.5 0.2 0.3 6.6 2.6 5.4 73.6 27.8 11.7 2.6 1.5 5.0 1.2 13.8 1.6 H1-1 "H1.1, H1a, H1F1, HIST1H1A" ENSG00000124610 "H1.1 linker histone, cluster member" Q02539 6 26017032-26017787 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "brain: 1.0" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 3.3;Cytotrophoblasts: 1.2;Extravillous trophoblasts: 4.2;Hofbauer cells: 2.0" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hypothalamus: 1.0" "Immune cell enhanced" "Detected in single" "T-reg: 1.7" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in single" "REH: 1.0" "Not detected" "Not detected" "HPA043753, HPA056830" Enhanced Supported Nucleoplasm NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 65: Brain - Ion transport" "Cluster 14: REH - Unknown function" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA043753: AB_2678654, HPA056830: " "unprognostic (3.80e-1)" "unprognostic (1.82e-1)" "unprognostic (1.15e-1)" "unprognostic (1.96e-1)" "unprognostic (1.21e-1)" "unprognostic (3.05e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.8 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.3 1.7 0.1 0.0 0.0 0.0 0.4 0.2 1.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 1.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 H1-4 "H1.4, H1e, H1F4, H1s-4, HIST1H1E" ENSG00000168298 "H1.4 linker histone, cluster member" P10412 6 26156329-26157115 "Disease related genes, Predicted intracellular proteins" DNA-binding "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 52.3;brain: 53.8" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 11.2;Cytotrophoblasts: 8.0;dendritic cells: 18.6;Extravillous trophoblasts: 11.3;Hofbauer cells: 7.7;Plasma cells: 6.7;Syncytiotrophoblasts: 7.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 53.8" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 10.5;U-266/70: 12.5;U-266/84: 15.1;U-87 MG: 12.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011506, HPA055907" Supported Supported "Nuclear speckles" NA Yes 8300000 "Cluster 6: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 16: U-266 - Nucleosome" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "CAB011506: AB_470256, HPA055907: AB_2682966" "unprognostic (6.96e-2)" "unprognostic (1.25e-1)" "unprognostic (3.06e-2)" "unprognostic (1.86e-1)" "unprognostic (9.62e-2)" "unprognostic (1.04e-2)" "unprognostic (5.78e-3)" "unprognostic (2.31e-2)" "unprognostic (1.24e-1)" "unprognostic (1.00e-1)" "unprognostic (1.20e-1)" "unprognostic (1.37e-1)" "unprognostic (7.72e-13)" "unprognostic (4.54e-3)" "unprognostic (3.46e-2)" "unprognostic (1.30e-3)" "unprognostic (2.18e-2)" 1.7 0.3 0.4 0.3 2.4 52.3 2.7 53.8 26.5 3.2 7.3 1.7 0.3 0.5 0.3 1.2 0.7 0.4 0.6 2.8 11.7 2.1 1.1 1.2 2.5 11.8 0.0 1.8 1.8 0.3 1.9 0.9 3.2 2.5 0.4 0.0 3.0 0.2 0.4 4.1 2.7 0.1 5.0 1.4 1.4 1.4 5.5 2.7 0.9 0.1 0.5 0.9 2.8 11.4 2.6 0.3 0.5 5.5 0.1 0.0 6.6 0.0 0.4 1.2 0.9 0.1 1.6 1.3 0.7 0.1 0.5 1.2 0.3 0.7 0.5 1.8 1.6 0.9 0.5 0.4 0.1 0.8 1.1 0.1 0.3 0.3 0.6 0.1 0.5 1.4 4.4 7.0 0.2 0.5 8.6 7.8 2.0 0.8 0.8 4.0 1.3 10.5 0.3 0.0 4.0 0.9 3.3 0.8 1.2 0.6 1.1 2.8 0.5 2.5 3.8 1.5 2.6 12.5 15.1 6.1 12.6 2.3 1.2 257.4 43.0 106.3 66.4 42.1 76.6 73.6 52.1 61.6 49.0 119.6 39.4 37.1 60.4 70.7 39.5 48.6 56.9 31.4 0.4 2.4 53.8 26.5 2.8 11.7 11.8 0.0 3.2 5.0 5.5 11.4 3.6 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 8.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 11.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 7.3 1.8 0.0 0.0 0.0 H2AC11 "H2A.1b, H2A/p, H2AFP, HIST1H2AG, pH2A/f" ENSG00000196787 "H2A clustered histone 11" P0C0S8 6 27133042-27135291 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 2.8;testis: 3.1" "Group enriched" "Detected in some" 10 "Cardiomyocytes: 1.2;Cytotrophoblasts: 2.0;dendritic cells: 1.5;Extravillous trophoblasts: 3.1;Hofbauer cells: 2.6;Plasma cells: 1.3;Syncytiotrophoblasts: 3.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 9.5" "Group enriched" "Detected in many" 5 "B-cells: 2.8;granulocytes: 9.5;T-cells: 2.9" "Cell line enhanced" "Detected in many" "K-562: 15.5;SiHa: 17.3;U-266/84: 48.8" "Low region specificity" "Detected in many" HPA041189 Supported Approved Nucleoplasm NA Yes "Cluster 38: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 16: U-266 - Nucleosome" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA041189: AB_2677357" "unprognostic (4.86e-2)" "unprognostic (6.89e-2)" "unprognostic (1.66e-1)" "unprognostic (3.94e-1)" "unprognostic (8.67e-2)" "unprognostic (1.03e-3)" "unprognostic (1.95e-1)" "unprognostic (5.78e-2)" "unprognostic (2.41e-1)" "unprognostic (2.37e-1)" "unprognostic (2.14e-3)" "unprognostic (1.53e-2)" "unprognostic (7.36e-2)" "unprognostic (5.98e-2)" "unprognostic (6.48e-2)" "unprognostic (8.22e-3)" "unprognostic (9.54e-2)" 0.3 0.3 0.7 0.3 0.9 2.4 2.8 0.5 0.7 0.5 0.7 0.9 1.3 0.1 0.6 0.6 0.2 0.3 0.2 0.6 1.0 0.2 0.5 0.3 1.0 1.5 1.4 0.1 0.2 0.0 0.1 0.4 1.4 0.7 0.7 0.1 0.1 0.4 0.2 0.2 1.1 0.2 1.2 0.9 0.5 3.1 1.7 1.9 0.3 0.3 0.4 0.4 0.4 1.7 2.1 2.8 2.3 2.0 7.1 1.5 1.5 0.7 1.1 2.4 0.3 1.2 2.1 0.7 3.0 0.9 2.3 4.2 2.8 1.2 1.6 3.7 1.6 1.1 5.2 0.0 1.5 1.1 2.2 2.7 0.5 0.7 0.8 1.2 0.8 2.0 15.5 6.9 0.1 2.7 2.9 1.8 1.3 3.1 1.9 1.9 2.3 8.0 0.4 0.5 9.0 2.1 17.3 2.7 1.0 1.1 0.0 0.7 0.9 2.6 5.8 2.1 1.1 12.4 48.8 4.9 0.5 1.7 1.6 9.5 0.3 0.6 0.4 0.2 0.9 2.3 1.7 1.1 0.5 2.8 1.4 1.3 2.3 0.9 0.6 1.0 2.9 5.3 0.7 0.9 0.5 0.7 0.6 1.0 1.5 1.4 1.4 1.2 1.7 1.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 2.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.0 0.2 0.0 0.0 0.0 H2AC12 "dJ86C11.1, H2A/S, H2AFALii, HIST1H2AH" ENSG00000274997 "H2A clustered histone 12" Q96KK5 6 27147106-27147562 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.8;brain: 2.8" "Cell type enhanced" "Detected in some" "dendritic cells: 1.6;Extravillous trophoblasts: 2.3;Hofbauer cells: 1.0" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "naive B-cell: 11.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEK 293: 5.4;MOLT-4: 6.2;NB-4: 6.9" "CAB004030, HPA041189" Supported Approved Nucleoplasm NA Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 24: NB-4 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB004030: AB_2118804, HPA041189: AB_2677357" "unprognostic (4.07e-1)" "unprognostic (2.73e-3)" "unprognostic (4.04e-2)" "unprognostic (4.01e-1)" "unprognostic (2.02e-1)" "unprognostic (5.35e-3)" "unprognostic (3.90e-2)" "unprognostic (3.20e-1)" "unprognostic (2.36e-1)" "unprognostic (2.38e-3)" "unprognostic (2.91e-1)" "unprognostic (2.32e-1)" "unprognostic (9.74e-3)" "unprognostic (1.87e-1)" "unprognostic (1.26e-4)" 0.2 0.1 0.5 0.0 0.9 8.8 0.3 0.7 0.5 0.2 0.8 0.7 0.2 0.0 0.0 0.2 0.2 0.1 0.1 0.3 0.9 0.0 0.1 0.2 1.1 1.6 1.3 0.1 0.1 0.1 0.0 0.3 1.8 0.1 0.1 0.0 0.1 0.0 0.0 0.2 2.1 0.1 1.8 0.6 0.2 1.6 2.0 1.5 0.1 0.0 0.2 0.2 0.2 2.8 1.7 2.0 0.7 3.0 0.0 0.0 0.4 0.2 0.3 0.3 0.0 2.0 0.6 2.7 0.6 0.0 0.3 0.2 0.6 0.0 0.0 1.4 5.4 3.0 2.5 0.0 0.0 2.1 1.1 0.0 0.0 0.7 0.0 0.0 0.5 1.1 3.1 1.7 0.5 0.3 6.2 6.9 2.1 0.6 0.7 2.2 1.9 3.2 0.0 0.2 1.5 0.4 0.9 0.3 0.2 0.0 0.6 1.0 0.0 0.6 1.7 0.1 1.8 1.8 2.0 4.0 0.8 2.8 0.6 0.0 0.8 0.0 2.2 2.3 1.0 3.3 4.1 3.8 2.0 11.9 2.1 1.5 0.0 5.1 1.4 1.4 0.7 2.0 0.5 0.9 0.7 0.5 0.3 0.9 1.6 1.3 1.8 1.8 2.0 2.8 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.9 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 H2AC14 "H2A/E, H2AFE, HIST1H2AJ" ENSG00000276368 "H2A clustered histone 14" Q99878 6 27814302-27814777 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "bone marrow: 7.2" "Cell type enhanced" "Detected in single" "Extravillous trophoblasts: 1.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "T-reg: 2.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 6.9;Karpas-707: 9.8;MCF7: 11.5" "Low region specificity" "Detected in many" HPA041189 Supported Approved Nucleoplasm NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA041189: AB_2677357" "unprognostic (8.95e-3)" "unprognostic (4.08e-3)" "unprognostic (3.28e-2)" "unprognostic (5.72e-3)" "unprognostic (2.29e-2)" "unprognostic (2.69e-2)" "unprognostic (6.06e-2)" "unprognostic (1.97e-2)" "unprognostic (1.05e-1)" "unprognostic (2.18e-1)" "unprognostic (9.39e-3)" "unprognostic (3.43e-1)" "unprognostic (9.35e-2)" "unprognostic (1.51e-1)" "unprognostic (1.88e-2)" 0.1 0.0 0.2 0.3 0.4 7.2 0.0 0.5 0.7 0.5 0.4 0.2 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.2 0.4 0.0 0.1 0.1 0.7 0.7 0.5 0.0 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.4 0.6 0.1 0.1 1.0 1.7 0.0 0.0 0.1 0.2 0.1 0.8 3.5 0.0 0.9 0.0 0.0 0.0 0.7 1.0 0.8 0.7 1.8 1.4 0.1 3.1 0.3 0.5 0.1 1.0 0.0 0.8 0.4 1.4 0.3 4.6 0.7 6.9 0.2 0.0 1.7 0.0 0.2 0.5 0.2 0.0 1.0 1.6 0.0 9.8 0.2 11.5 5.0 4.6 1.4 1.5 2.4 4.6 0.0 1.4 0.1 1.9 0.3 0.8 0.8 1.0 0.3 0.2 0.3 3.4 0.0 0.0 1.6 0.3 0.1 4.8 3.1 2.9 0.8 3.2 2.2 0.0 0.0 0.0 0.2 0.2 0.4 0.3 1.3 1.3 1.1 1.3 0.4 0.1 1.1 0.1 0.1 0.1 2.8 1.7 0.2 0.4 0.5 0.7 0.2 0.4 0.7 0.5 1.3 0.4 1.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 H2AC20 "H2A, H2A/q, H2AFQ, HIST2H2AC" ENSG00000184260 "H2A clustered histone 20" Q16777 1 149886918-149887411 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 25.3;brain: 27.2;choroid plexus: 20.0" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 5.7;dendritic cells: 8.1;Extravillous trophoblasts: 18.2;Hofbauer cells: 9.7;Syncytiotrophoblasts: 8.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 60.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041189 Supported Approved Nucleoplasm NA Yes "Cluster 1: Neutrophils - Mixed function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA041189: AB_2677357" "unprognostic (5.50e-3)" "unprognostic (4.97e-2)" "unprognostic (9.34e-2)" "unprognostic (6.95e-2)" "unprognostic (1.49e-1)" "unprognostic (9.78e-3)" "unprognostic (1.01e-1)" "unprognostic (2.25e-1)" "unprognostic (1.81e-1)" "unprognostic (3.24e-2)" "unprognostic (4.25e-2)" "unprognostic (7.87e-2)" "prognostic unfavorable (1.20e-10)" "unprognostic (1.42e-1)" "unprognostic (1.73e-1)" "unprognostic (4.89e-2)" "prognostic favorable (7.86e-5)" 3.8 3.6 15.5 0.8 20.6 25.3 3.5 24.0 14.0 5.4 20.0 3.1 0.2 2.0 0.0 2.2 2.7 0.4 2.6 10.0 27.2 2.3 2.6 4.7 0.5 19.8 13.1 4.3 2.4 0.1 3.0 0.5 16.7 3.2 0.1 0.5 1.4 0.1 0.7 4.5 3.3 0.4 19.9 5.2 2.5 1.2 18.2 1.6 1.8 0.0 0.1 2.5 4.1 18.2 3.9 4.2 5.0 15.7 0.0 0.7 7.8 1.2 0.9 2.4 3.3 2.5 1.1 8.0 0.2 0.2 0.5 2.0 0.3 1.6 0.0 0.7 5.7 1.9 1.6 12.2 0.0 4.7 4.6 0.9 0.2 0.2 0.5 0.1 1.6 2.0 1.7 10.0 0.5 60.6 5.7 5.4 6.7 4.5 10.0 1.8 2.2 1.4 1.0 2.4 1.8 7.5 3.2 1.2 3.8 0.4 0.6 4.4 1.5 1.1 10.9 1.9 2.9 5.5 4.0 4.2 2.9 6.3 2.3 47.2 33.8 19.0 22.9 22.6 20.2 13.1 20.1 18.5 17.7 33.1 14.0 14.8 98.4 19.1 25.6 24.9 16.3 22.6 15.5 20.6 24.0 14.0 10.0 27.2 19.8 13.1 16.7 19.9 18.2 18.2 2.4 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 5.7 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 18.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 8.8 1.5 0.0 0.0 0.0 H2AC7 "H2A.3, H2A/g, H2AFG, HIST1H2AD" ENSG00000196866 "H2A clustered histone 7" P20671 6 26198784-26199293 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 17.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 17.5;U-266/84: 6.3" "Low region specificity" "Detected in all" HPA041189 Supported Approved Nucleoplasm NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 29: U-266 - Adaptive immune response" Nucleoplasm "HPA041189: AB_2677357" "unprognostic (5.03e-2)" "unprognostic (1.11e-2)" "unprognostic (7.27e-2)" "unprognostic (3.56e-1)" "unprognostic (9.17e-2)" "unprognostic (1.45e-1)" "unprognostic (9.09e-3)" "unprognostic (6.72e-2)" "unprognostic (1.92e-1)" "unprognostic (4.34e-1)" "unprognostic (1.81e-1)" "unprognostic (2.88e-2)" "unprognostic (1.10e-9)" "unprognostic (2.00e-1)" "unprognostic (1.34e-1)" "unprognostic (3.27e-1)" "unprognostic (2.14e-2)" 0.7 0.2 0.4 0.3 1.7 2.9 0.6 4.1 2.1 3.3 3.6 0.5 0.0 0.1 0.0 2.5 0.6 0.3 0.4 1.0 1.9 0.6 1.2 2.1 0.5 3.1 1.7 0.7 0.1 0.0 0.3 0.2 2.1 2.1 0.1 0.0 0.5 0.0 0.0 1.1 0.5 0.0 3.9 1.2 0.6 0.3 3.0 1.8 0.3 0.0 0.3 0.3 2.8 6.8 1.1 0.0 0.2 0.2 0.0 0.0 0.2 0.7 0.1 1.1 0.0 1.3 0.4 0.7 1.2 0.2 0.1 0.3 0.0 0.1 0.2 0.0 1.0 0.3 1.4 1.3 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.1 0.0 0.7 2.5 1.3 0.0 0.0 3.7 1.5 1.1 0.0 1.1 1.0 0.4 0.9 0.4 0.1 1.4 0.2 0.6 0.8 0.1 0.0 1.4 0.3 0.0 1.1 3.1 0.0 1.0 17.5 6.3 2.2 1.0 1.3 0.4 2.3 0.3 3.8 1.3 1.9 1.3 2.7 2.0 4.0 1.1 7.6 1.9 1.9 17.9 1.8 2.2 6.2 2.7 0.8 0.4 1.7 4.1 2.1 1.0 1.9 3.1 1.7 2.1 3.9 3.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 H2AX H2AFX ENSG00000188486 "H2A.X variant histone" P16104 11 119093854-119095467 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair, Host-virus interaction, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 43.7;Cytotrophoblasts: 83.2;dendritic cells: 34.0;Extravillous trophoblasts: 106.6;Hofbauer cells: 45.8;Syncytiotrophoblasts: 64.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012264, HPA041189, HPA051647" Supported Supported "Nucleoplasm,Nuclear speckles" Yes Yes "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Nuclear speckles" "CAB012264: AB_297215, HPA041189: AB_2677357, HPA051647: AB_2681563" "unprognostic (1.44e-1)" "unprognostic (1.96e-1)" "unprognostic (6.46e-2)" "unprognostic (6.41e-2)" "unprognostic (3.07e-1)" "unprognostic (3.25e-1)" "prognostic unfavorable (1.51e-4)" "unprognostic (2.32e-3)" "unprognostic (1.93e-1)" "unprognostic (3.07e-3)" "unprognostic (6.78e-2)" "unprognostic (9.31e-2)" "prognostic unfavorable (5.47e-9)" "unprognostic (1.21e-3)" "unprognostic (1.20e-1)" "unprognostic (1.20e-1)" "unprognostic (1.99e-2)" 13.2 20.7 35.2 12.6 37.8 24.9 8.0 39.0 42.2 13.3 20.6 18.6 13.3 14.0 2.1 43.6 13.1 3.1 13.4 33.7 32.3 17.0 13.9 14.3 16.0 43.9 38.9 18.7 11.6 3.4 24.3 11.0 37.8 15.7 4.3 6.6 11.4 4.7 12.4 18.1 18.8 3.5 38.0 24.0 16.1 15.4 37.8 30.5 10.4 3.6 12.0 11.8 15.7 51.8 132.1 77.9 120.3 72.3 10.9 7.9 126.4 146.0 44.0 80.3 70.4 124.0 55.1 89.7 85.9 34.0 60.5 134.0 57.5 41.7 21.5 133.4 161.0 182.2 20.7 129.8 11.4 90.5 108.9 6.7 9.0 34.2 21.0 13.1 40.7 115.4 149.9 143.1 38.9 335.6 207.8 269.9 87.5 60.0 162.6 200.7 141.6 42.7 37.5 56.3 127.6 152.0 116.0 66.6 20.6 20.6 99.8 68.2 50.9 77.7 204.2 63.8 110.2 38.7 40.8 92.3 17.9 145.2 155.0 3.8 1.3 4.2 1.6 0.6 0.8 0.9 1.7 1.7 1.8 0.8 1.1 1.0 0.6 2.2 0.8 0.8 1.6 1.2 35.2 37.8 39.0 42.2 33.7 32.3 43.9 38.9 37.8 38.0 37.8 51.8 43.7 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.0 0.0 0.0 83.2 34.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 106.6 9.4 0.0 0.0 0.0 0.0 0.0 0.0 45.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 64.2 7.2 0.0 0.0 0.0 H2BC21 "H2B, H2B.1, H2B/q, H2BE, H2BFQ, HIST2H2BE" ENSG00000184678 "H2B clustered histone 21" Q16778 1 149884459-149886652 "Predicted intracellular proteins" "Antibiotic, Antimicrobial, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 86.5;Syncytiotrophoblasts: 160.2" "Cancer enhanced" "Detected in all" "prostate cancer: 87.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 58.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 58.6" "Cell line enhanced" "Detected in many" "Karpas-707: 56.8;U-266/70: 93.7;U-266/84: 53.8" "Low region specificity" "Detected in all" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA Yes "Cluster 50: Neutrophils - Cellular senescence" "Cluster 27: Brain & Skin - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm Cytosol "HPA042205: AB_2677900, HPA043013: AB_2678269, HPA048671: AB_2680488" "unprognostic (1.49e-1)" "unprognostic (3.10e-2)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.63e-1)" "unprognostic (1.89e-1)" "unprognostic (2.52e-1)" "unprognostic (1.37e-1)" "unprognostic (8.28e-2)" "unprognostic (4.65e-2)" "unprognostic (3.27e-1)" "unprognostic (1.91e-1)" "unprognostic (1.30e-1)" "unprognostic (4.74e-2)" "unprognostic (4.41e-2)" "unprognostic (7.82e-2)" "unprognostic (2.20e-1)" "unprognostic (2.86e-3)" 17.8 15.3 35.1 7.2 40.2 21.2 17.7 38.7 38.7 60.8 38.7 22.0 5.2 7.4 22.8 41.7 27.5 5.5 77.3 33.5 37.2 46.3 18.0 37.2 6.2 41.6 38.0 61.7 13.4 9.5 32.5 14.8 39.0 95.2 6.1 69.1 23.5 6.6 62.8 84.0 14.8 6.2 41.0 27.3 32.0 13.7 38.9 20.1 15.2 29.2 3.4 25.1 79.5 55.8 2.8 2.8 4.5 0.9 23.5 6.3 2.2 9.7 6.5 4.0 1.3 1.1 4.4 0.5 2.6 8.6 5.7 10.9 3.6 1.7 2.2 3.4 2.8 0.8 11.5 2.1 7.4 0.8 12.6 21.4 7.9 1.7 6.6 4.8 1.3 4.0 12.0 56.8 5.0 16.8 3.1 5.1 2.8 22.6 5.8 3.6 1.7 13.7 3.8 2.3 30.3 4.9 33.4 4.5 2.7 10.7 23.4 2.4 1.7 3.0 33.6 2.2 0.9 93.7 53.8 2.6 4.0 3.6 1.9 21.3 4.8 8.2 1.3 6.2 2.3 1.5 1.8 2.1 3.3 3.8 2.2 2.2 58.6 1.3 12.3 8.9 2.2 10.1 35.1 40.2 38.7 38.7 33.5 37.2 41.6 38.0 39.0 41.0 38.9 55.8 1.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 86.5 0.0 0.0 0.0 0.0 25.5 2.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 20.2 4.6 0.0 0.0 0.0 0.0 0.0 0.0 27.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 160.2 0.3 0.0 0.0 0.0 H2BC5 "H2B/b, H2BFB, HIST1H2BD" ENSG00000158373 "H2B clustered histone 5" P58876 6 26158146-26171349 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 151.7" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 22.4;Syncytiotrophoblasts: 39.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 117.9;U-266/84: 134.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042205, HPA043013, HPA048671, CAB062336" Supported Approved Nucleoplasm,Cytosol NA Yes "Cluster 6: Non-specific - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm Cytosol "CAB062336: AB_10622324, HPA042205: AB_2677900, HPA043013: AB_2678269, HPA048671: AB_2680488" "unprognostic (2.39e-2)" "unprognostic (1.58e-2)" "prognostic unfavorable (3.84e-4)" "unprognostic (1.32e-1)" "unprognostic (1.98e-1)" "unprognostic (2.83e-2)" "unprognostic (1.54e-1)" "unprognostic (8.10e-2)" "unprognostic (2.28e-1)" "unprognostic (3.54e-2)" "unprognostic (3.68e-3)" "unprognostic (2.17e-1)" "unprognostic (4.74e-3)" "unprognostic (1.08e-1)" "unprognostic (1.56e-1)" "unprognostic (3.91e-2)" "unprognostic (1.34e-2)" 25.4 13.4 17.8 7.6 21.9 53.8 18.5 48.7 19.2 151.7 41.8 34.6 11.0 6.3 27.7 37.6 53.5 15.3 31.4 17.9 29.7 67.2 62.9 36.8 9.2 22.2 23.7 101.8 15.7 2.1 30.5 9.3 28.0 144.0 17.1 9.7 28.9 3.6 18.5 44.1 23.3 4.3 27.5 35.4 26.1 11.3 23.8 35.2 25.2 7.3 4.1 17.9 95.5 33.9 17.9 39.7 12.0 6.8 91.2 8.3 3.6 15.5 8.9 19.6 12.3 13.3 14.5 8.1 95.2 18.5 21.8 27.9 6.8 6.6 9.2 36.6 16.9 5.4 33.7 14.5 9.8 7.2 14.7 59.7 10.3 5.5 7.7 7.6 4.9 7.5 57.1 43.3 3.6 64.2 16.4 18.1 12.6 76.1 18.2 6.5 7.6 54.4 18.7 12.8 38.1 16.1 96.8 25.1 15.9 23.1 63.4 2.6 3.0 24.4 63.4 9.9 3.3 117.9 134.9 20.5 3.1 33.2 5.0 35.3 2.3 16.9 8.1 5.1 10.4 13.4 12.3 13.5 5.6 20.0 11.4 8.7 24.8 10.5 6.9 19.3 8.9 2.4 17.8 21.9 48.7 19.2 17.9 29.7 22.2 23.7 28.0 27.5 23.8 33.9 1.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.4 0.0 0.0 0.0 0.0 7.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 7.5 1.5 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 39.4 0.3 0.0 0.0 0.0 H3-3B "H3.3B, H3F3B" ENSG00000132475 "H3.3 histone B" P84243 17 75776434-75785893 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 4220.9" "Cell type enhanced" "Detected in some" "Adipocytes: 1321.3;Cytotrophoblasts: 1625.3;dendritic cells: 844.9;Extravillous trophoblasts: 1626.9;Hofbauer cells: 1908.9;Syncytiotrophoblasts: 3503.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 21089.7" "Lineage enriched" "Detected in all" 6 "granulocytes: 21089.7" "Low cell line specificity" "Detected in all" "CAB037166, CAB037187, CAB037221, HPA042570" Supported Enhanced Nucleoplasm NA Yes "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB037166: AB_2115285, CAB037187: AB_477069, CAB037221: AB_477076, HPA042570: AB_2678056" "unprognostic (1.66e-1)" "unprognostic (8.42e-3)" "unprognostic (3.42e-2)" "unprognostic (1.06e-1)" "unprognostic (1.81e-1)" "unprognostic (1.95e-1)" "unprognostic (2.41e-1)" "unprognostic (2.43e-3)" "unprognostic (3.37e-2)" "unprognostic (1.64e-1)" "unprognostic (5.88e-2)" "unprognostic (1.07e-1)" "unprognostic (1.26e-3)" "unprognostic (9.20e-2)" "unprognostic (4.81e-2)" "unprognostic (2.33e-1)" "unprognostic (1.99e-1)" 607.2 369.9 223.8 532.5 262.6 4220.9 628.9 264.4 288.8 741.2 186.6 415.4 329.9 507.4 180.3 798.6 585.7 467.9 312.8 210.7 226.0 438.3 380.2 553.2 509.1 268.7 241.9 1166.0 578.0 341.1 357.5 427.1 242.8 348.2 223.1 299.8 519.2 237.1 332.5 1153.2 407.5 322.9 253.7 449.9 393.0 654.3 246.0 464.0 500.7 155.6 296.2 545.3 675.2 316.1 1386.5 1194.2 490.0 486.1 273.3 424.9 675.1 636.7 557.1 764.8 609.3 1290.7 952.6 683.6 593.1 373.2 539.5 530.0 390.5 881.0 432.0 375.9 883.0 612.8 668.2 1112.0 615.7 1029.2 755.0 467.3 534.2 785.6 1004.7 339.3 582.5 437.8 885.6 1193.0 399.4 2015.3 1492.3 859.5 394.8 442.8 1322.8 1091.7 894.2 746.6 607.3 803.5 988.1 1096.0 645.8 933.7 1402.2 259.3 734.2 1091.3 549.1 1359.7 1205.2 595.2 1721.1 1431.3 932.2 843.5 720.5 967.6 761.1 7991.0 3667.6 10060.5 2613.4 3365.8 2482.2 3199.5 2474.2 2478.9 3218.1 2813.7 2635.4 2173.4 21089.7 3240.7 3199.0 3294.6 2999.0 9615.0 223.8 262.6 264.4 288.8 210.7 226.0 268.7 241.9 242.8 253.7 246.0 316.1 1321.3 0.0 0.0 0.0 294.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 398.6 0.0 0.0 0.0 0.0 1625.3 844.9 0.0 0.0 0.0 0.0 0.0 0.0 172.3 0.0 0.0 0.0 0.0 1626.9 485.1 0.0 0.0 0.0 0.0 0.0 0.0 1908.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 257.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 314.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 377.9 0.0 0.0 0.0 0.0 3503.3 211.7 0.0 0.0 0.0 H3C10 "H3/k, H3F1K, H3FK, HIST1H3H" ENSG00000278828 "H3 clustered histone 10" P68431 6 27810064-27811300 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 6.4" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 4.4;Extravillous trophoblasts: 3.1;Hofbauer cells: 2.3;Syncytiotrophoblasts: 5.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 8 "basophil: 101.9;neutrophil: 37.8" "Lineage enriched" "Detected in all" 12 "granulocytes: 101.9" "Cell line enhanced" "Detected in many" "K-562: 33.7;SiHa: 28.3;U-266/70: 23.5;U-266/84: 61.3" HPA042570 Approved NA Yes "Cluster 34: Basophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 24: Non-specific - Transcription regulation" "HPA042570: AB_2678056" "unprognostic (1.61e-1)" "prognostic favorable (4.35e-4)" "unprognostic (1.79e-1)" "unprognostic (1.63e-2)" "unprognostic (3.68e-2)" "unprognostic (2.27e-1)" "unprognostic (1.29e-1)" "unprognostic (3.01e-1)" "unprognostic (2.12e-1)" "unprognostic (2.93e-1)" "prognostic unfavorable (9.25e-6)" "unprognostic (1.09e-1)" "prognostic unfavorable (5.73e-5)" "unprognostic (4.09e-1)" "unprognostic (4.94e-1)" "unprognostic (3.70e-1)" "unprognostic (2.82e-2)" 1.6 1.3 0.9 0.4 0.8 4.4 0.8 0.8 1.1 2.1 1.9 2.8 1.3 0.3 0.5 3.3 0.8 0.4 1.0 1.0 0.7 1.1 2.4 4.0 1.0 1.2 1.1 1.9 0.2 0.8 0.4 0.9 1.0 2.6 2.6 0.1 0.6 0.2 0.6 1.3 1.3 0.2 1.0 6.4 1.5 1.4 1.0 3.1 1.2 1.1 0.4 0.6 2.9 1.8 1.9 7.2 3.0 2.5 4.2 0.5 0.4 1.0 0.7 3.4 1.3 2.2 2.1 1.3 6.5 0.8 2.0 3.9 1.1 1.7 2.2 9.2 4.4 1.8 6.9 9.3 1.1 1.6 2.7 5.6 0.5 0.7 0.8 1.5 1.4 1.7 33.7 15.5 0.7 14.5 3.0 3.6 1.5 13.3 2.7 1.6 0.0 17.0 3.6 0.8 9.3 1.8 28.3 5.7 1.2 1.6 13.4 0.5 1.6 1.5 4.5 0.9 0.4 23.5 61.3 5.0 0.1 7.9 0.3 101.9 4.2 9.2 1.4 1.3 1.7 1.4 2.2 2.0 3.3 5.3 1.4 1.1 37.8 1.7 1.5 7.1 8.1 203.1 0.9 0.8 0.8 1.1 1.0 0.7 1.2 1.1 1.0 1.0 1.0 1.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 4.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.2 0.3 0.0 0.0 0.0 H4C15 "H4/o, HIST2H4B" ENSG00000270276 "H4 clustered histone 15" P62805 1 149854045-149861210 "Disease related genes, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "SCLC-21H: 4.8;SiHa: 7.5;U-266/70: 8.6;U-266/84: 7.6" "Low region specificity" "Detected in all" HPA042201 Supported NA Yes 25000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA042201: AB_2677898" "unprognostic (8.20e-2)" "unprognostic (2.69e-1)" "unprognostic (1.77e-1)" 2.0 3.2 2.5 0.1 2.5 2.1 1.7 2.4 3.5 2.6 1.3 4.0 1.7 2.2 2.5 1.0 2.8 0.7 2.2 2.5 1.8 2.4 1.7 1.7 1.3 1.6 1.8 1.8 1.6 2.0 4.9 0.9 1.6 3.5 1.0 3.1 1.4 1.1 2.4 2.3 1.7 2.2 2.7 2.3 2.2 0.8 1.6 4.6 2.0 1.1 0.6 2.8 1.5 2.0 0.0 0.0 0.8 0.2 0.8 0.8 0.1 1.4 2.6 0.2 0.0 0.0 0.5 0.8 1.3 0.7 0.2 0.0 0.4 0.0 0.1 1.5 0.5 0.0 3.1 0.0 0.0 0.0 0.0 2.1 0.0 0.2 0.0 1.1 1.0 1.9 0.0 4.5 0.1 3.1 0.2 0.5 0.1 0.8 0.0 1.1 0.3 0.1 0.3 0.6 4.8 2.9 7.5 0.8 0.3 0.0 1.6 0.1 1.8 0.3 1.8 0.5 0.2 8.6 7.6 1.2 0.7 0.2 1.1 1.8 1.3 1.6 1.4 2.1 2.5 1.8 1.6 1.2 1.9 4.3 1.3 2.3 5.8 1.3 1.2 2.4 2.5 3.4 2.5 2.5 2.4 3.5 2.5 1.8 1.6 1.8 1.6 2.7 1.6 2.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 H4C3 "dJ221C16.1, H4/g, H4FG, HIST1H4C" ENSG00000197061 "H4 clustered histone 3" P62805 6 26103933-26104337 "Disease related genes, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 47 "brain: 238.7" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 200.9;Cytotrophoblasts: 584.5;Extravillous trophoblasts: 700.1;Hofbauer cells: 264.1;Syncytiotrophoblasts: 220.3" "Cancer enhanced" "Detected in many" "ovarian cancer: 12.8" "Region enriched" "Detected in all" 5 "cerebellum: 238.7" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 39.5;PC-3: 21.4" HPA042201 Supported NA Yes 25000000 "Cluster 6: Non-specific - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" "HPA042201: AB_2677898" "unprognostic (1.28e-1)" "unprognostic (5.91e-4)" "unprognostic (6.95e-2)" "unprognostic (8.93e-3)" "unprognostic (5.84e-2)" "unprognostic (2.17e-1)" "unprognostic (1.38e-1)" "unprognostic (4.31e-3)" "unprognostic (3.79e-1)" "unprognostic (1.01e-2)" "unprognostic (2.30e-2)" "unprognostic (1.32e-1)" "prognostic unfavorable (5.74e-6)" "unprognostic (2.42e-2)" "unprognostic (3.02e-1)" "unprognostic (2.82e-1)" "unprognostic (2.79e-3)" 0.2 0.2 28.3 0.9 52.6 5.0 0.2 238.7 33.5 0.4 0.6 1.0 0.3 0.6 0.0 0.7 0.5 0.1 0.1 21.1 37.6 0.6 0.6 0.2 2.1 8.1 28.8 0.4 0.4 0.1 0.2 0.4 19.4 0.2 1.1 0.4 1.8 0.3 0.1 0.3 0.5 0.0 25.9 1.0 0.4 0.6 39.9 3.7 1.2 0.0 1.7 0.8 0.1 39.1 2.3 2.1 0.8 3.3 0.0 0.4 0.0 1.3 1.0 0.7 1.6 3.3 0.6 0.8 1.0 0.4 0.9 1.2 2.5 0.7 0.6 1.9 39.5 1.5 4.5 5.0 1.0 1.8 1.3 1.7 0.0 0.5 0.0 0.0 0.9 0.6 2.3 1.6 0.6 1.1 8.9 4.4 2.1 1.5 21.4 2.5 1.2 3.7 1.4 0.2 2.2 1.4 1.1 1.5 0.9 0.9 1.0 5.4 0.6 2.3 2.4 1.1 1.9 3.1 3.2 4.4 1.4 3.3 1.2 605.5 279.8 218.0 343.5 117.8 331.0 645.7 432.0 285.4 218.9 559.1 496.9 378.6 509.7 325.0 128.7 317.6 322.8 2335.9 28.3 52.6 238.7 33.5 21.1 37.6 8.1 28.8 19.4 25.9 39.9 39.1 25.3 0.0 0.0 0.0 13.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 200.9 0.0 0.0 0.0 0.0 584.5 76.4 0.0 0.0 0.0 0.0 0.0 0.0 41.5 0.0 0.0 0.0 0.0 700.1 54.9 0.0 0.0 0.0 0.0 0.0 0.0 264.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.3 0.0 0.0 0.0 0.0 220.3 13.0 0.0 0.0 0.0 HADH "HADH1, HADHSC, SCHAD" ENSG00000138796 "Hydroxyacyl-CoA dehydrogenase" Q16836 4 107989714-108035174 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Oxidoreductase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 280.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 272.4;Proximal enterocytes: 383.0;Proximal tubular cells: 318.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039588, HPA043888" Enhanced Supported Mitochondria No Yes 1000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA039588: AB_10673425, HPA043888: AB_2678716" "unprognostic (1.73e-1)" "unprognostic (3.32e-3)" "unprognostic (3.05e-3)" "unprognostic (8.86e-3)" "unprognostic (1.83e-1)" "unprognostic (6.83e-2)" "unprognostic (9.26e-3)" "unprognostic (1.55e-2)" "unprognostic (9.22e-2)" "unprognostic (3.24e-2)" "unprognostic (2.96e-1)" "unprognostic (1.18e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.67e-1)" "unprognostic (4.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.88e-2)" 143.0 54.1 23.2 20.9 23.8 27.4 74.9 24.6 26.3 37.9 33.5 101.2 84.4 49.8 24.9 34.2 56.2 24.0 175.6 22.9 27.2 140.2 225.5 22.8 22.2 24.7 26.3 54.3 42.1 40.2 18.0 13.7 26.0 35.4 90.8 10.4 55.9 42.4 249.7 28.0 89.1 72.7 26.0 18.0 60.7 27.9 24.9 76.0 37.7 280.3 28.5 34.1 28.7 28.0 32.2 27.9 64.3 46.2 149.2 48.2 27.0 43.1 68.5 49.6 48.9 21.2 60.9 185.0 23.5 38.8 34.6 42.0 85.5 64.5 55.5 49.6 37.2 39.9 50.5 48.9 24.3 88.2 17.0 50.4 34.1 35.1 32.3 41.4 34.4 127.1 53.1 98.7 57.3 58.9 163.6 36.7 29.0 147.8 30.1 113.5 84.3 89.2 54.5 129.4 73.2 43.1 41.1 161.9 45.6 37.0 77.4 70.8 20.6 35.5 18.9 48.5 26.7 52.1 63.3 80.6 47.0 60.2 27.0 0.0 11.1 11.4 17.2 14.2 22.1 31.4 19.5 20.7 36.8 27.1 22.4 22.2 1.2 36.7 20.1 41.7 17.7 16.3 23.2 23.8 24.6 26.3 22.9 27.2 24.7 26.3 26.0 26.0 24.9 28.0 17.3 28.9 33.8 11.1 25.7 15.6 54.2 65.8 41.5 6.9 46.5 56.1 225.6 52.9 48.1 35.0 4.2 41.0 18.3 164.7 160.4 43.3 196.8 41.4 22.6 17.5 32.4 65.6 15.1 32.2 44.7 28.2 52.5 26.1 10.8 63.9 21.0 272.4 116.5 6.7 18.9 93.3 36.7 37.8 11.8 108.5 46.3 25.3 21.4 12.2 15.3 26.8 8.2 9.5 9.9 23.0 100.8 35.3 32.0 33.9 383.0 318.8 70.8 6.8 39.5 21.7 38.2 22.4 20.3 64.0 18.2 17.0 19.6 66.3 194.2 49.1 HELLS "LSH, Nbla10143, PASG, SMARCA6" ENSG00000119969 "Helicase, lymphoid specific" Q9NRZ9 10 94501434-94613905 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" "Developmental protein, Helicase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.3;lymphoid tissue: 15.9" "Cell type enhanced" "Detected in many" "Spermatocytes: 182.0;Spermatogonia: 173.9" "Cancer enhanced" "Detected in all" "testis cancer: 16.1" "Region enhanced" "Detected in many" "cerebellum: 5.5" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 36.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004491, HPA063242" Enhanced Approved "Nucleoplasm,Golgi apparatus,Vesicles" No Yes "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus, Vesicles" "CAB004491: AB_627895, HPA063242: AB_2684968" "unprognostic (1.94e-1)" "prognostic favorable (1.36e-4)" "unprognostic (9.85e-2)" "unprognostic (3.38e-2)" "unprognostic (8.65e-2)" "unprognostic (4.85e-3)" "unprognostic (1.76e-5)" "unprognostic (7.59e-3)" "unprognostic (7.03e-3)" "unprognostic (6.49e-2)" "unprognostic (2.05e-2)" "unprognostic (9.45e-5)" "unprognostic (9.93e-13)" "unprognostic (2.25e-2)" "unprognostic (1.72e-1)" "unprognostic (6.24e-2)" "unprognostic (3.03e-2)" 1.1 1.2 0.8 6.4 0.3 16.3 3.0 5.5 1.2 3.2 1.3 4.3 2.9 2.9 1.4 5.9 1.7 2.0 0.7 0.4 1.3 2.5 1.8 1.7 12.4 0.8 0.8 2.6 1.2 1.4 3.0 4.1 1.0 2.1 5.1 1.1 1.9 1.0 0.3 5.3 3.9 2.2 0.9 4.3 3.7 12.8 0.9 15.9 1.1 0.2 12.6 3.6 3.2 1.5 57.7 55.4 70.6 90.1 2.9 6.4 37.4 42.9 27.8 34.4 54.6 70.3 45.5 70.0 16.7 15.5 29.1 56.3 40.9 34.9 50.7 68.5 45.5 37.3 56.3 58.0 1.7 71.2 31.6 3.6 2.0 42.1 20.0 9.4 24.0 46.0 20.7 43.5 43.1 54.9 75.2 35.6 73.4 42.3 24.1 70.3 62.1 16.3 24.2 72.2 28.4 22.8 50.3 14.5 7.8 59.0 60.9 23.1 17.2 38.4 19.4 35.4 52.4 22.3 47.6 74.5 19.0 42.8 17.9 0.3 0.7 0.0 7.0 1.5 2.4 18.8 11.4 9.4 2.3 23.2 5.2 7.7 1.0 10.2 1.0 36.8 19.7 2.3 0.8 0.3 5.5 1.2 0.4 1.3 0.8 0.8 1.0 0.9 0.9 1.5 4.7 9.6 3.9 0.0 19.7 21.5 11.5 12.6 13.1 16.4 10.0 15.0 1.0 12.8 12.6 22.0 0.0 46.3 13.2 26.2 3.9 9.0 2.0 9.3 16.4 8.1 10.8 50.5 3.3 6.2 43.4 13.0 17.9 16.3 5.7 60.6 5.7 3.6 15.1 6.7 5.4 17.8 8.2 2.2 10.3 5.3 9.0 7.3 1.8 9.4 5.7 4.3 1.0 4.5 6.6 4.7 1.8 5.7 37.5 3.7 1.7 1.6 6.3 11.4 19.7 10.5 16.4 182.0 173.9 22.9 9.9 11.1 15.7 16.5 30.9 11.7 HJURP "DKFZp762E1312, FAKTS, hFLEG1, URLC9" ENSG00000123485 "Holliday junction recognition protein" Q8NCD3 2 233833416-233854566 "Predicted intracellular proteins" "Cell cycle" "Chaperone, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.4;lymphoid tissue: 30.4" "Cell type enhanced" "Detected in many" "Early spermatids: 17.4;Erythroid cells: 38.3;Extravillous trophoblasts: 16.1;Granulosa cells: 14.8;Spermatocytes: 37.5;Spermatogonia: 16.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA008436, HPA027261" Uncertain Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitochondria" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli, Nucleoli rim" Mitochondria "HPA008436: AB_1850757, HPA027261: AB_2672184" "unprognostic (5.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.87e-1)" "unprognostic (1.44e-3)" "unprognostic (3.62e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (3.37e-5)" "prognostic unfavorable (2.46e-4)" "prognostic unfavorable (6.49e-4)" "unprognostic (9.48e-2)" "prognostic unfavorable (7.72e-5)" "unprognostic (7.60e-2)" "unprognostic (0.00e+0)" "unprognostic (7.42e-2)" "unprognostic (5.58e-2)" "unprognostic (1.89e-2)" "unprognostic (5.74e-2)" 0.6 0.6 0.0 5.5 0.1 47.4 1.1 0.1 0.2 0.8 0.1 3.9 4.1 0.9 0.2 5.6 0.3 0.5 0.3 0.1 0.1 0.4 0.8 1.4 12.6 0.1 0.3 0.2 0.2 0.1 0.1 3.0 0.1 0.4 5.2 0.1 1.0 0.1 0.2 3.6 3.8 1.9 0.0 4.1 2.4 11.1 0.3 30.4 0.3 0.0 12.0 1.4 2.0 0.2 54.5 73.6 68.4 32.7 2.6 5.4 42.8 79.5 37.9 55.2 59.9 51.3 57.6 17.1 9.0 31.4 98.0 61.7 54.9 40.9 72.6 40.0 21.6 65.5 61.4 50.9 0.3 54.1 43.2 1.8 1.5 45.1 30.9 15.7 35.5 51.3 56.6 40.8 103.0 55.3 76.4 59.7 58.9 42.2 49.1 58.4 103.0 30.3 28.6 32.3 39.4 24.7 45.8 34.2 31.7 31.0 25.7 42.1 26.0 59.6 64.6 44.3 87.2 38.6 32.7 67.9 35.7 39.3 151.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.4 0.0 1.2 0.4 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.3 0.1 0.0 0.3 0.2 0.2 0.0 0.5 0.0 2.9 1.3 0.5 1.9 0.0 0.0 0.7 0.5 1.2 0.0 2.1 0.0 0.0 8.2 0.5 5.6 0.0 0.2 17.4 0.3 1.3 1.1 0.0 38.3 0.0 0.0 16.1 2.0 5.1 1.3 0.0 14.8 2.2 0.3 7.1 0.0 0.0 3.5 0.0 3.0 2.9 9.0 0.6 3.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.0 11.4 1.0 0.5 0.1 0.1 0.0 0.0 0.1 1.9 37.5 16.3 8.9 0.9 1.5 2.3 0.3 7.6 0.9 HMGB2 HMG2 ENSG00000164104 "High mobility group box 2" P26583 4 173331376-173334432 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, DNA recombination, Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 12 "bone marrow: 2347.2;lymphoid tissue: 939.2" "Cell type enhanced" "Detected in all" "Erythroid cells: 1915.4;Extravillous trophoblasts: 872.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 798.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 2454.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003506, CAB037206, HPA053314, HPA073663" Enhanced Supported Nucleoplasm,Nucleoli "Secreted to blood" NA Yes 1200000 "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "CAB037206: AB_1079071, HPA003506: AB_1079070, HPA053314: AB_2682109, HPA073663: " "unprognostic (2.82e-1)" "unprognostic (8.52e-3)" "unprognostic (2.56e-1)" "unprognostic (8.37e-2)" "unprognostic (8.05e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (3.76e-5)" "unprognostic (2.12e-1)" "prognostic unfavorable (3.13e-4)" "unprognostic (4.41e-2)" "prognostic unfavorable (7.04e-4)" "unprognostic (9.65e-2)" "prognostic unfavorable (7.60e-12)" "unprognostic (1.60e-2)" "unprognostic (2.83e-2)" "unprognostic (2.68e-2)" "unprognostic (1.21e-2)" 90.3 31.0 36.3 146.1 38.4 2347.2 89.1 35.4 49.9 79.0 33.0 117.1 93.2 92.3 47.3 115.6 78.8 43.5 85.8 33.2 38.3 74.3 37.8 83.8 390.4 37.5 36.8 118.9 27.2 18.3 35.4 111.0 38.0 46.9 122.2 134.1 59.8 35.2 72.4 75.1 108.7 65.5 36.3 159.5 66.0 136.0 36.1 939.2 56.4 57.0 388.9 68.2 86.1 40.1 498.2 114.6 976.8 444.4 118.2 118.2 375.1 366.3 271.3 386.7 345.7 329.0 673.6 1645.5 79.2 203.0 207.4 190.3 645.0 196.1 601.0 1004.0 303.4 1823.2 308.8 487.8 115.7 1642.8 683.4 114.7 59.2 194.2 439.1 211.5 402.8 866.1 703.9 2282.4 358.9 409.9 2454.9 1513.7 355.4 289.4 199.3 1226.7 499.7 620.4 227.0 208.8 838.6 759.0 365.5 209.6 166.6 340.8 291.1 1173.2 236.0 175.5 513.6 219.0 554.9 734.8 437.1 1869.4 149.1 1178.4 464.4 798.0 135.9 407.0 94.1 57.6 86.2 72.5 137.8 131.1 112.8 57.6 88.4 85.3 316.7 83.0 49.1 43.2 266.4 107.6 36.3 38.4 35.4 49.9 33.2 38.3 37.5 36.8 38.0 36.3 36.1 40.1 167.0 28.9 64.1 5.9 153.2 158.8 141.5 131.8 75.1 48.9 75.3 107.8 229.0 38.6 78.3 55.2 35.5 472.6 222.9 116.5 142.8 25.9 30.4 71.2 71.7 128.0 74.7 1915.4 2.7 16.1 872.5 121.5 63.2 76.5 110.6 210.5 171.7 26.5 210.1 45.4 4.7 191.2 109.9 295.0 142.9 33.1 105.3 233.9 67.6 6.5 241.9 81.8 132.8 1.0 4.8 11.3 75.2 57.6 268.6 114.2 65.4 51.0 149.8 143.5 78.9 71.7 134.4 493.6 400.9 233.6 134.0 128.7 289.5 42.3 284.7 89.0 HMMR "CD168, RHAMM" ENSG00000072571 "Hyaluronan mediated motility receptor" O75330 5 163460203-163491941 "CD markers, FDA approved drug targets, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.6;lymphoid tissue: 27.3;testis: 27.5" "Cell type enhanced" "Detected in many" "Early spermatids: 86.2;Erythroid cells: 133.3;Extravillous trophoblasts: 55.1;Late spermatids: 60.9;Spermatocytes: 100.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB002433, HPA040025, HPA043926, HPA061524" Enhanced Enhanced Microtubules,Centrosome,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules "Centrosome, Cytosol" "CAB002433: AB_564080, HPA040025: AB_2676805, HPA043926: , HPA061524: AB_2684551" "unprognostic (3.53e-3)" "unprognostic (1.01e-1)" "unprognostic (3.38e-3)" "unprognostic (8.88e-3)" "unprognostic (2.12e-1)" "prognostic unfavorable (5.52e-4)" "prognostic unfavorable (1.93e-7)" "prognostic unfavorable (1.09e-4)" "unprognostic (5.68e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (3.71e-5)" "unprognostic (1.02e-1)" "unprognostic (0.00e+0)" "unprognostic (1.65e-2)" "unprognostic (4.98e-2)" "unprognostic (2.39e-1)" "unprognostic (1.77e-2)" 0.8 0.7 0.2 10.1 0.3 20.6 2.1 0.3 0.4 1.1 0.1 6.6 7.4 0.8 0.2 4.0 0.5 0.9 0.8 0.2 0.2 0.7 1.7 0.9 18.1 0.5 0.3 0.2 0.3 0.9 0.2 6.2 0.4 0.5 8.8 0.8 0.8 0.2 1.2 4.2 6.5 2.9 0.3 2.9 3.6 27.5 0.7 27.3 0.7 0.4 17.7 2.2 1.4 0.5 77.0 47.2 94.5 50.8 5.0 9.0 70.3 71.4 34.9 88.0 78.9 96.8 145.1 127.5 66.0 22.2 118.5 86.3 112.4 69.0 148.6 116.1 34.4 76.7 32.3 48.4 1.4 68.7 67.3 2.4 4.1 82.8 64.0 14.7 50.6 85.7 73.2 101.0 93.2 28.5 72.3 38.8 81.9 51.2 51.6 78.0 126.3 63.9 34.8 20.4 78.8 43.8 106.3 32.8 38.6 45.1 97.3 54.5 32.9 63.2 52.4 50.6 97.2 53.7 96.3 102.4 41.4 104.2 61.1 0.2 0.2 0.0 0.1 0.1 0.3 0.3 0.3 0.1 0.2 0.2 0.1 0.2 0.1 0.5 0.0 0.6 1.5 0.2 0.2 0.3 0.3 0.4 0.2 0.2 0.5 0.3 0.4 0.3 0.7 0.5 0.4 0.0 1.1 1.3 6.0 2.5 1.8 4.5 2.8 0.6 3.2 3.7 2.5 4.3 3.2 0.0 0.0 37.3 2.3 5.3 0.0 0.8 86.2 3.8 3.1 3.1 1.2 133.3 0.6 0.2 55.1 4.6 11.7 5.7 0.0 21.6 5.3 3.8 22.2 0.0 0.4 7.8 6.1 8.8 2.7 60.9 2.1 7.6 0.0 0.0 2.3 0.1 1.0 0.5 1.2 0.2 0.3 0.7 22.9 1.5 1.3 2.6 2.8 1.0 6.6 0.6 3.8 100.9 23.3 14.1 1.4 4.5 5.2 1.6 15.6 3.0 HNRNPF HNRPF ENSG00000169813 "Heterogeneous nuclear ribonucleoprotein F" P52597 10 43385617-43409166 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA016884, HPA069667" Supported Enhanced Nucleoplasm NA Yes 2500000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 6: T47d - Mammary gland" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA016884: AB_1856444, HPA069667: AB_2686166" "unprognostic (9.93e-2)" "unprognostic (2.26e-2)" "unprognostic (1.81e-1)" "unprognostic (3.65e-2)" "unprognostic (6.39e-2)" "unprognostic (3.33e-2)" "prognostic unfavorable (5.85e-4)" "unprognostic (1.51e-2)" "unprognostic (6.37e-2)" "unprognostic (6.33e-3)" "unprognostic (4.89e-3)" "unprognostic (1.07e-2)" "unprognostic (1.95e-2)" "unprognostic (3.77e-3)" "unprognostic (3.35e-1)" "unprognostic (3.71e-1)" "unprognostic (2.22e-1)" 114.6 77.7 43.3 133.9 48.6 161.3 102.9 49.8 47.9 86.8 65.2 124.5 134.2 78.3 58.9 114.9 119.4 88.9 63.7 40.2 45.9 94.4 173.2 97.6 181.4 52.4 51.4 87.3 87.5 73.1 50.5 113.6 51.5 90.8 118.9 80.4 85.2 74.8 93.6 104.5 130.7 89.1 49.2 123.5 118.0 84.0 49.4 193.3 72.7 79.6 182.8 160.0 81.8 58.3 292.1 302.9 184.2 280.7 220.5 239.5 269.1 222.5 371.0 305.6 358.2 285.5 394.7 581.8 139.2 242.0 179.3 401.7 496.8 363.6 249.5 245.6 297.2 371.2 178.6 370.9 271.4 550.5 360.9 293.2 282.4 237.6 434.6 177.1 266.4 281.3 382.0 256.2 234.2 453.4 542.5 300.5 139.5 439.1 252.4 449.0 172.7 276.8 314.9 442.7 226.1 226.8 226.6 410.4 344.3 199.2 457.4 265.3 200.4 140.1 264.4 231.8 356.8 228.5 415.8 352.6 227.1 520.0 139.7 205.5 234.9 227.2 247.0 269.2 301.0 238.9 256.6 273.3 251.8 200.7 213.8 204.0 152.2 287.9 253.6 140.6 315.8 460.5 43.3 48.6 49.8 47.9 40.2 45.9 52.4 51.4 51.5 49.2 49.4 58.3 223.8 134.6 102.8 13.4 206.9 336.0 336.5 204.9 189.5 51.4 156.8 126.4 66.3 157.3 147.9 112.2 47.9 292.9 201.7 164.7 176.1 218.6 360.1 203.8 153.3 176.6 126.8 199.6 10.8 142.2 414.8 157.0 154.9 147.0 116.1 106.9 127.5 222.3 226.0 48.8 12.0 230.1 164.8 193.3 181.7 92.7 146.0 178.5 99.6 24.4 213.0 116.9 219.4 16.6 32.7 161.4 152.1 117.8 163.3 280.8 189.7 233.1 242.0 163.6 98.6 179.7 278.1 184.5 167.3 210.2 330.5 210.4 229.9 126.3 238.8 314.0 HP1BP3 HP1-BP74 ENSG00000127483 "Heterochromatin protein 1 binding protein 3" Q5SSJ5 1 20740266-20787323 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028215, HPA054295" Supported Supported "Nuclear speckles" NA Yes 30000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear speckles" "HPA028215: AB_10601021, HPA054295: AB_2682440" "unprognostic (3.90e-3)" "unprognostic (6.83e-2)" "unprognostic (7.69e-2)" "unprognostic (3.66e-2)" "unprognostic (1.31e-1)" "unprognostic (1.25e-3)" "prognostic unfavorable (2.76e-4)" "unprognostic (1.97e-1)" "unprognostic (3.26e-2)" "unprognostic (1.68e-1)" "unprognostic (1.94e-2)" "unprognostic (9.50e-2)" "unprognostic (6.86e-2)" "unprognostic (1.65e-1)" "unprognostic (6.30e-2)" "unprognostic (1.27e-1)" "unprognostic (2.43e-2)" 87.9 78.9 62.2 76.2 75.1 141.7 80.1 69.6 76.5 143.6 62.1 107.9 71.3 116.5 63.0 94.8 96.7 75.3 75.7 64.5 66.6 83.5 66.5 84.1 91.4 68.1 64.4 135.6 74.4 98.1 60.9 85.9 67.5 81.3 88.2 96.4 83.0 74.3 113.9 86.9 93.8 100.3 61.3 89.2 83.1 54.5 68.7 134.5 106.3 78.7 90.3 93.9 114.2 107.6 207.3 106.1 261.6 157.5 152.3 172.8 157.3 230.2 182.4 156.7 163.1 97.6 232.0 208.2 113.4 176.6 108.4 171.9 136.7 125.5 199.8 306.5 124.7 296.2 230.5 85.4 98.1 209.7 181.7 135.1 90.6 159.0 208.5 193.0 160.5 245.1 169.9 251.8 180.1 64.2 323.5 93.0 69.3 152.6 126.3 250.4 255.0 219.2 113.6 66.6 175.0 180.0 279.8 112.9 181.2 132.9 117.3 138.7 196.4 176.2 164.2 180.7 139.2 144.0 194.2 246.7 150.2 213.0 204.0 102.4 55.3 202.6 57.1 45.0 59.7 70.8 61.9 62.1 52.2 58.4 80.4 54.5 66.1 63.3 54.9 59.5 71.6 49.0 62.2 75.1 69.6 76.5 64.5 66.6 68.1 64.4 67.5 61.3 68.7 107.6 129.4 150.6 156.2 96.9 112.1 130.4 137.4 81.6 159.9 117.8 116.6 108.7 161.4 94.4 94.5 104.8 54.2 87.6 144.7 105.6 154.6 87.0 40.8 85.3 184.6 136.8 103.7 214.6 98.3 93.4 70.7 161.9 98.8 128.2 137.8 131.8 129.2 101.0 72.6 80.8 93.7 113.4 83.4 100.7 104.1 22.3 172.7 116.9 113.8 130.2 111.2 119.5 127.7 142.7 189.9 113.0 90.1 162.5 162.0 124.6 91.7 110.7 54.6 97.6 157.8 145.2 148.3 141.3 110.1 201.8 134.5 92.9 151.9 116.2 115.3 118.4 HROB "C17orf53, MCM8IP, MGC3130" ENSG00000125319 "Homologous recombination factor with OB-fold" Q8N3J3 17 44141906-44162476 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, DNA synthesis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 9.3;testis: 11.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.3;Cytotrophoblasts: 3.4;Extravillous trophoblasts: 8.6;Hofbauer cells: 2.9;Syncytiotrophoblasts: 1.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023004, HPA023393, HPA024430" Uncertain Approved Nucleoplasm,Cytosol NA Yes "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Cytosol" "HPA023004: AB_1853877, HPA023393: AB_1853878, HPA024430: AB_1853879" "unprognostic (1.72e-1)" "unprognostic (5.95e-2)" "unprognostic (2.43e-2)" "prognostic unfavorable (8.08e-4)" "unprognostic (1.59e-1)" "unprognostic (7.37e-2)" "prognostic unfavorable (3.46e-4)" "prognostic unfavorable (9.39e-4)" "unprognostic (1.90e-1)" "unprognostic (2.89e-1)" "unprognostic (3.66e-4)" "unprognostic (2.86e-1)" "unprognostic (0.00e+0)" "unprognostic (3.06e-2)" "unprognostic (5.88e-2)" "unprognostic (3.65e-2)" "unprognostic (8.40e-2)" 1.5 0.4 0.1 1.1 0.1 9.3 1.4 0.4 0.3 0.9 0.0 0.9 0.9 0.8 0.1 2.7 0.5 0.2 0.7 0.1 0.2 0.4 0.6 0.6 1.6 0.3 0.2 0.8 0.3 0.4 0.4 0.9 0.3 0.7 1.0 0.3 0.7 0.3 0.9 1.7 0.9 0.7 0.1 1.3 0.6 11.4 0.2 2.3 0.3 0.2 1.9 0.6 1.2 0.3 8.9 11.1 8.3 7.6 0.6 2.3 9.8 6.7 5.9 12.8 13.9 11.3 5.4 9.4 5.8 5.8 13.3 7.5 10.9 10.5 11.1 10.6 14.0 6.0 10.1 7.7 0.3 6.6 7.3 1.9 1.6 15.7 7.7 1.5 5.3 10.2 13.8 11.6 6.2 6.7 15.7 10.2 5.6 4.0 10.8 10.0 13.2 11.6 3.0 7.0 5.1 2.9 4.1 4.0 3.4 9.4 8.1 7.7 2.4 12.1 9.5 8.3 9.9 6.7 12.2 8.0 5.7 5.1 7.1 0.0 0.2 0.2 0.2 0.2 0.0 0.1 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.0 0.1 0.9 0.4 0.1 0.1 0.1 0.4 0.3 0.1 0.2 0.3 0.2 0.3 0.1 0.2 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 3.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 HSP90AB1 "HSPC2, HSPCB" ENSG00000096384 "Heat shock protein 90 alpha family class B member 1" P08238 6 44246166-44253888 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Stress response" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 4755.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005230, HPA055729, HPA072606, HPA074351" Enhanced Supported Cytosol "Intracellular and membrane" NA Yes 63000000 "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB005230: AB_2121392, HPA055729: AB_2682899, HPA072606: AB_2732203, HPA074351: AB_2732252" "unprognostic (6.12e-3)" "unprognostic (2.96e-3)" "unprognostic (4.72e-2)" "unprognostic (9.24e-2)" "unprognostic (4.20e-1)" "unprognostic (1.15e-3)" "unprognostic (1.76e-3)" "unprognostic (2.74e-1)" "unprognostic (7.97e-2)" "prognostic favorable (4.03e-4)" "unprognostic (1.31e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (9.94e-4)" "unprognostic (3.02e-1)" "unprognostic (9.53e-2)" "unprognostic (2.63e-1)" "unprognostic (1.06e-1)" 584.8 719.5 647.1 368.9 700.4 466.4 507.6 675.2 1529.5 581.3 651.0 425.3 215.8 594.2 540.1 463.8 708.5 332.5 783.8 699.9 811.5 494.6 396.5 526.9 427.7 707.0 738.2 1204.8 722.9 606.0 574.8 451.9 764.3 471.2 389.8 339.5 410.2 491.9 1379.0 483.7 332.6 526.8 655.1 346.0 538.8 251.6 745.8 362.1 456.8 998.8 571.4 525.0 509.4 818.8 2393.2 1495.7 1298.1 1606.0 871.2 904.4 1355.3 1049.1 1021.8 1898.3 1325.5 2254.5 708.0 3029.2 1106.3 1099.8 1928.1 1349.9 3197.5 1563.4 2326.7 1010.5 1292.5 2359.3 793.9 2978.8 628.9 2386.2 1563.2 842.6 1034.9 1495.5 1277.7 1658.4 1847.6 1533.9 3210.4 1095.1 1309.8 2404.3 2003.1 1432.6 1519.7 4378.9 1129.7 1900.7 1325.9 1658.7 1287.7 1422.1 1891.1 1154.8 816.3 1164.8 1526.2 1751.5 1518.6 1178.2 1169.0 1124.0 1875.7 931.1 2440.0 1255.6 2125.8 5370.7 1221.7 1720.8 1312.1 65.9 231.7 52.8 343.7 341.0 577.8 544.0 380.3 395.0 375.1 473.1 509.3 494.0 27.3 434.9 349.0 232.1 326.8 678.5 647.1 700.4 675.2 1529.5 699.9 811.5 707.0 738.2 764.3 655.1 745.8 818.8 1165.2 897.4 678.2 70.5 906.4 1059.3 4755.7 862.6 1331.1 329.3 938.9 1418.3 1407.0 519.0 942.6 366.0 227.2 1104.3 629.3 538.6 729.8 1011.1 185.5 1385.8 1359.6 1070.6 567.4 775.9 103.5 688.9 1107.1 1247.3 616.2 1444.8 1003.4 761.3 360.5 360.3 807.5 339.9 151.0 578.2 518.8 314.5 1262.5 198.4 686.0 896.7 736.4 76.8 573.3 326.1 200.8 69.9 127.4 811.7 504.8 611.2 725.0 1810.6 361.5 664.8 1219.1 262.1 348.4 1512.7 1437.2 266.1 694.1 1232.8 923.5 1123.3 1265.6 1350.0 739.6 2408.7 HSPA1A "HSP70-1, HSPA1" ENSG00000204389 "Heat shock protein family A (Hsp70) member 1A" P0DMV8 6 31815543-31817946 "Disease related genes, Predicted intracellular proteins" "Host-virus interaction, Stress response" "Chaperone, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 7514.5;Langerhans cells: 2690.4;Urothelial cells: 3444.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 64 "cerebral cortex: 403.6" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 6.8;monocytes: 3.6;T-cells: 3.0" "Cell line enriched" "Detected in some" 8 "HEK 293: 4450.4" "CAB017451, CAB032815, HPA052504" Supported Approved Nucleoplasm,Vesicles,Cytosol "Intracellular and membrane" NA Yes 47000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Vesicles" Cytosol "CAB017451: AB_10013742, CAB032815: AB_627759, HPA052504: AB_2681854" "unprognostic (2.44e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (1.54e-5)" "unprognostic (6.86e-2)" "unprognostic (2.01e-1)" "unprognostic (1.98e-1)" "unprognostic (1.18e-2)" "unprognostic (6.17e-3)" "unprognostic (2.47e-2)" "unprognostic (1.74e-2)" "unprognostic (8.43e-3)" "unprognostic (1.43e-1)" "unprognostic (1.47e-1)" "unprognostic (2.38e-1)" "unprognostic (6.48e-2)" "unprognostic (4.12e-2)" "unprognostic (1.51e-1)" 640.5 350.5 3.5 12.7 3.8 0.0 167.2 6.3 403.6 414.1 3.4 497.7 0.0 209.7 15.9 452.9 194.6 5.9 927.7 4.3 3.7 745.9 1116.2 1055.0 9.1 5.4 5.1 369.7 308.2 1.1 474.3 12.0 4.0 427.7 4.2 6.5 111.5 0.5 294.4 257.3 174.4 2.2 3.8 451.9 483.2 98.0 3.7 2.5 340.2 0.3 2.3 569.2 553.7 6.1 0.2 524.1 0.0 0.1 20.1 14.4 0.0 0.3 0.0 0.0 0.0 1.6 0.7 0.0 122.9 28.7 0.0 0.4 0.0 34.1 0.0 6.9 4450.4 0.0 1.7 3.1 0.0 1.1 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.0 1.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 33.4 0.0 0.5 0.7 0.0 0.0 16.6 5.3 0.0 0.1 4.1 0.0 49.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.3 2.3 3.2 1.1 3.6 0.7 0.6 1.6 1.4 0.3 0.2 0.7 0.6 6.8 0.8 2.0 0.3 3.0 0.4 3.5 3.8 6.3 403.6 4.3 3.7 5.4 5.1 4.0 3.8 3.7 6.1 1537.0 147.4 97.0 427.4 312.4 362.4 7514.5 125.5 968.7 305.3 782.0 844.3 1010.7 81.5 109.3 126.9 379.5 43.2 148.1 634.6 41.1 86.8 81.0 534.7 488.1 1049.0 469.2 64.0 9.7 21.6 154.1 1208.6 592.8 753.4 445.4 18.1 123.5 95.2 270.4 205.3 11.4 560.1 114.0 319.0 2690.4 49.5 603.0 1715.2 839.6 398.2 126.6 768.2 15.5 17.1 207.0 39.5 668.8 160.6 1173.3 1404.1 68.4 72.9 177.2 690.2 151.2 443.4 1802.0 65.4 148.8 1105.8 336.3 104.3 1382.2 285.6 454.9 3444.4 HSPA1B HSP70-2 ENSG00000204388 "Heat shock protein family A (Hsp70) member 1B" P0DMV9 6 31827738-31830254 "Predicted intracellular proteins" "Host-virus interaction, Stress response" "Chaperone, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 3007.4;Urothelial cells: 1619.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "Karpas-707: 204.3" "CAB008640, HPA052504" Approved Approved Nucleoplasm,Vesicles,Cytosol NA Yes "Cluster 18: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Cytosol" Nucleoplasm "CAB008640: AB_1617331, HPA052504: AB_2681854" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (4.23e-3)" "unprognostic (3.23e-2)" "unprognostic (3.54e-1)" "unprognostic (1.15e-1)" "unprognostic (2.76e-3)" "unprognostic (9.50e-2)" "unprognostic (3.45e-1)" "unprognostic (4.42e-2)" "unprognostic (6.92e-2)" "unprognostic (4.88e-2)" "unprognostic (5.74e-2)" "unprognostic (1.15e-1)" "unprognostic (9.17e-3)" "unprognostic (4.69e-2)" "unprognostic (5.99e-2)" 526.3 340.1 0.7 0.4 1.3 0.0 126.0 1.6 5.6 475.3 0.6 361.2 0.0 154.0 9.1 375.2 231.5 2.3 718.3 1.1 1.9 555.5 685.4 845.3 0.0 0.8 1.0 682.2 336.5 3.3 438.2 0.0 1.2 303.6 0.5 2.6 94.8 0.3 159.9 299.0 139.1 0.0 0.4 274.7 372.0 93.8 1.5 0.0 289.9 0.0 0.0 415.3 503.3 1.2 0.4 24.1 0.4 0.2 1.1 0.0 0.3 0.2 0.0 0.0 0.0 1.0 0.1 0.0 8.4 0.0 0.0 3.3 0.0 0.0 0.0 0.0 15.4 0.0 0.5 2.2 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 204.3 0.0 3.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.5 0.0 1.7 0.0 1.6 0.0 0.0 0.3 3.2 0.0 0.4 41.5 0.4 0.4 0.4 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 1.3 1.6 5.6 1.1 1.9 0.8 1.0 1.2 0.4 1.5 1.2 563.2 112.2 75.0 140.7 242.7 239.2 3007.4 63.2 630.0 44.6 509.4 403.9 512.3 40.0 73.7 69.9 131.3 82.7 82.8 542.8 19.6 45.5 1.9 434.9 380.2 446.2 318.6 57.9 2.7 15.6 140.8 585.8 595.8 710.4 346.8 14.1 25.7 17.7 142.0 47.1 2.8 426.3 61.1 84.4 1140.4 9.8 220.6 627.1 642.1 126.5 17.7 192.4 1.0 5.5 61.8 21.4 524.1 54.9 967.0 584.2 159.1 38.3 75.0 144.2 105.2 226.4 846.5 15.2 46.4 904.0 221.9 259.7 604.6 116.7 400.5 1619.4 HSPA8 "HSC70, HSC71, HSP73, HSPA10" ENSG00000109971 "Heat shock protein family A (Hsp70) member 8" P11142 11 123057489-123063230 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, Stress response, Transcription, Transcription regulation" "Chaperone, Hydrolase, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 2455.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002056, HPA052504" Uncertain Approved Nucleoplasm,Vesicles NA Yes 140000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm Vesicles "CAB002056: , HPA052504: AB_2681854" "unprognostic (2.28e-3)" "unprognostic (1.19e-3)" "prognostic favorable (6.14e-6)" "unprognostic (1.75e-1)" "unprognostic (1.84e-2)" "unprognostic (5.70e-2)" "prognostic unfavorable (1.93e-4)" "unprognostic (9.65e-3)" "unprognostic (3.82e-1)" "unprognostic (9.64e-2)" "unprognostic (2.93e-1)" "unprognostic (3.22e-1)" "prognostic favorable (3.81e-4)" "unprognostic (2.53e-1)" "unprognostic (1.83e-1)" "unprognostic (2.74e-1)" "unprognostic (7.16e-2)" 539.8 604.9 456.3 542.1 498.1 442.4 448.9 591.6 887.9 326.6 571.4 435.8 506.9 367.3 614.7 554.2 498.5 508.6 892.4 535.1 614.9 850.5 763.2 480.1 685.0 564.8 564.2 421.4 1238.1 593.8 501.9 487.1 620.0 411.2 525.8 531.5 404.1 439.8 1519.0 224.4 453.5 508.4 554.2 520.3 676.7 395.0 559.8 628.6 422.6 1508.5 879.6 866.0 302.4 656.8 1369.6 2077.3 1370.5 1176.5 1259.4 1337.4 1775.6 2730.9 1550.4 3373.2 2004.8 3151.7 1787.3 2318.5 1614.6 1591.9 2337.3 1835.9 4091.6 1027.2 3323.5 1955.4 605.9 2570.4 881.5 1532.0 347.5 2418.0 1757.1 721.8 1594.5 1045.0 320.7 1753.4 1845.6 321.7 2727.8 1147.0 2704.5 1235.5 2507.0 1761.3 2063.2 3463.3 1874.0 2214.4 962.2 1281.3 1665.1 1008.4 1371.8 1023.9 1980.4 2110.5 763.6 1491.1 1837.1 901.9 1767.0 1621.1 1246.1 1404.5 2402.7 740.6 1985.0 1890.9 1791.1 3316.9 1970.0 517.7 592.3 587.8 1245.4 1159.8 1499.6 1009.2 1441.8 1366.1 656.1 752.2 1367.5 1326.5 201.8 1110.7 1255.0 465.5 1761.7 3439.4 456.3 498.1 591.6 887.9 535.1 614.9 564.8 564.2 620.0 554.2 559.8 656.8 795.5 192.3 228.2 72.5 576.3 282.3 2455.6 315.3 507.6 206.7 454.5 380.1 396.3 278.8 352.8 130.6 127.2 926.1 740.3 513.1 528.3 589.0 49.8 404.1 380.1 512.8 519.8 551.7 33.4 628.8 1032.6 609.7 366.0 366.5 434.8 633.8 249.9 223.9 810.9 181.7 45.6 511.1 303.2 359.8 1060.8 58.2 222.4 590.6 528.3 35.6 530.9 307.4 639.5 28.1 50.3 513.8 552.1 270.0 573.6 779.5 823.0 1002.2 465.7 278.1 243.3 416.3 893.1 248.9 419.2 590.6 284.6 1512.1 1123.5 430.3 632.0 1171.5 HSPE1 "CPN10, EPF, GroES, HSP10" ENSG00000115541 "Heat shock protein family E (Hsp10) member 1" P61604 2 197500140-197503449 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Stress response" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1077.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 1907.6;Proximal tubular cells: 1978.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 4135.5" "Low region specificity" "Detected in all" "CAB017366, HPA038755, HPA048272" Supported NA Yes 2500000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 65: Brain - Ion transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "CAB017366: AB_10998950, HPA038755: AB_2676190, HPA048272: AB_2680336" "unprognostic (2.75e-2)" "unprognostic (6.89e-2)" "unprognostic (1.86e-1)" "unprognostic (1.43e-2)" "unprognostic (1.98e-1)" "unprognostic (1.85e-2)" "unprognostic (5.83e-3)" "unprognostic (4.14e-2)" "unprognostic (1.26e-2)" "unprognostic (2.94e-3)" "unprognostic (1.39e-2)" "unprognostic (6.21e-3)" "unprognostic (2.63e-1)" "unprognostic (4.51e-2)" "unprognostic (6.30e-2)" "unprognostic (1.94e-1)" "unprognostic (7.08e-3)" 152.1 709.5 383.2 143.9 387.5 116.8 212.7 410.3 1077.6 122.3 402.1 257.2 164.9 84.3 213.0 132.9 131.4 97.4 208.0 383.7 400.8 410.7 662.7 111.0 154.5 400.9 394.7 130.1 112.6 173.0 125.5 164.0 399.9 137.9 246.3 85.8 121.9 114.8 181.4 80.5 168.2 116.8 403.6 86.5 130.5 58.7 391.2 144.8 104.5 213.1 207.9 216.6 85.5 440.8 593.1 926.1 675.1 521.5 560.5 314.0 905.5 586.2 307.9 620.8 577.3 2796.6 504.6 1079.2 782.2 333.8 1542.1 510.4 1895.0 681.2 782.0 512.3 874.7 1099.8 1789.0 4135.5 239.0 1503.6 497.2 382.4 532.1 577.8 297.6 392.7 631.0 720.9 1588.2 338.0 481.1 1027.2 1107.2 1706.9 1077.5 985.2 1513.4 747.6 568.2 1388.5 967.4 1028.3 581.5 375.1 546.4 713.9 545.5 1588.2 287.1 881.7 355.7 466.1 643.3 501.0 1019.4 427.8 1016.0 1758.3 515.6 726.7 640.6 33.2 95.5 24.4 166.3 174.5 216.3 287.1 223.6 210.1 156.6 221.8 251.7 264.1 12.6 200.3 143.1 263.4 198.7 176.0 383.2 387.5 410.3 1077.6 383.7 400.8 400.9 394.7 399.9 403.6 391.2 440.8 341.6 195.5 160.2 0.0 380.6 435.1 1907.6 690.4 301.7 90.7 393.6 511.2 355.6 381.8 363.3 195.0 250.2 839.3 334.4 553.8 911.7 354.0 22.3 520.7 291.3 296.3 440.3 233.1 0.0 231.2 634.0 370.0 274.2 493.3 324.6 215.7 94.6 1092.0 517.2 63.9 0.0 605.0 427.2 150.6 616.4 36.1 216.6 534.4 409.1 0.0 214.2 204.2 133.9 0.0 0.0 285.3 466.2 141.8 323.4 830.7 562.1 1978.2 475.8 160.2 131.5 283.6 642.5 140.0 241.9 381.2 371.8 976.7 685.9 791.7 775.5 1111.7 HSPH1 "HSP105A, HSP105B, KIAA0201, NY-CO-25" ENSG00000120694 "Heat shock protein family H (Hsp110) member 1" Q92598 13 31134973-31162388 "Cancer-related genes, Predicted intracellular proteins" "Stress response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "brain: 1251.1" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 1316.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebral cortex: 1251.1" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002060, HPA028675, HPA031569" Uncertain Enhanced Nucleoplasm,Cytosol No Yes 1300000 "Cluster 27: Non-specific - Gene expression" "Cluster 10: Brain - Neuronal signaling" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" Cytosol Nucleoplasm "CAB002060: AB_563775, HPA028675: AB_10601581, HPA031569: AB_2673938" "unprognostic (1.10e-2)" "unprognostic (4.94e-2)" "unprognostic (5.44e-2)" "unprognostic (1.36e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.90e-4)" "prognostic unfavorable (1.41e-5)" "unprognostic (5.03e-2)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (1.53e-1)" "unprognostic (3.13e-1)" "unprognostic (7.45e-3)" "unprognostic (9.61e-2)" "unprognostic (2.58e-1)" "unprognostic (2.04e-1)" "unprognostic (7.89e-2)" 52.2 42.1 175.9 23.5 193.6 20.7 27.9 175.2 1251.1 25.0 182.5 29.3 11.3 25.9 37.6 35.8 54.8 32.3 57.3 184.9 189.3 73.5 47.6 66.6 34.9 172.7 180.7 56.3 28.6 30.3 63.8 37.8 180.9 28.4 25.3 26.7 20.1 29.3 36.6 21.7 20.4 28.0 177.2 32.3 53.1 67.8 190.2 37.4 32.2 32.6 45.1 58.8 35.4 227.4 69.9 130.7 105.1 10.2 99.1 56.0 70.0 117.8 104.6 179.0 82.8 154.9 105.4 179.6 71.9 82.4 253.7 131.2 411.7 104.8 229.2 141.6 51.7 155.7 69.3 137.2 32.3 109.1 118.8 35.5 236.5 119.6 68.3 93.0 105.4 62.0 132.7 27.8 127.4 94.7 158.1 124.2 150.3 338.6 96.6 122.5 85.8 58.9 135.0 83.5 108.5 90.1 107.4 104.0 56.6 160.6 35.0 104.7 64.4 61.3 77.4 89.2 132.4 21.8 76.0 150.6 51.0 129.8 104.7 1.4 5.0 2.7 7.6 12.2 9.4 11.1 9.7 11.8 8.4 10.6 14.7 13.8 0.5 16.7 19.6 6.6 7.0 7.7 175.9 193.6 175.2 1251.1 184.9 189.3 172.7 180.7 180.9 177.2 190.2 227.4 171.1 131.4 87.7 36.6 130.8 214.6 1316.2 44.7 175.2 38.7 152.2 143.3 163.6 40.0 123.3 46.0 417.0 23.2 78.9 153.2 29.4 49.8 100.0 346.1 140.1 132.3 227.7 58.9 121.0 35.9 64.2 249.6 94.3 250.6 248.6 61.7 26.4 25.7 90.6 30.3 77.7 159.0 65.1 38.6 452.1 36.5 33.8 281.3 163.7 55.3 42.6 28.2 26.8 30.7 53.2 45.5 154.0 39.1 142.0 426.3 18.2 31.6 290.5 79.0 39.5 98.1 153.1 161.3 164.6 151.1 143.3 42.5 363.8 58.5 166.1 511.8 HYLS1 FLJ32915 ENSG00000198331 "HYLS1 centriolar and ciliogenesis associated" Q96M11 11 125883614-125900646 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 26.5" "Cell type enhanced" "Detected in many" "Early spermatids: 80.8;Late spermatids: 54.9;Spermatocytes: 92.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041210 Enhanced Supported "Plasma membrane,Cytosol" NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 78: Testis - Spermatogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "HPA041210: AB_10794987" "unprognostic (2.46e-1)" "unprognostic (1.60e-1)" "unprognostic (1.49e-1)" "unprognostic (2.35e-1)" "unprognostic (3.53e-3)" "unprognostic (1.17e-2)" "prognostic unfavorable (1.92e-4)" "unprognostic (3.28e-1)" "unprognostic (1.04e-3)" "unprognostic (6.56e-3)" "unprognostic (7.63e-2)" "unprognostic (4.81e-3)" "unprognostic (3.00e-2)" "unprognostic (2.19e-1)" "unprognostic (2.49e-1)" "unprognostic (1.03e-1)" "unprognostic (4.56e-2)" 2.9 2.4 5.7 3.0 5.3 2.4 4.3 8.0 8.5 4.2 4.9 4.7 6.0 3.8 6.7 3.7 4.2 2.6 5.0 5.4 5.3 5.5 5.8 2.5 6.2 5.0 4.7 3.9 2.2 2.7 2.3 4.4 5.0 5.0 5.0 4.3 3.1 6.1 2.7 4.8 3.3 6.4 4.5 3.6 5.4 26.5 6.0 5.2 2.5 4.3 9.0 3.8 2.3 5.2 11.2 23.9 8.4 5.9 16.5 11.6 14.8 27.3 10.9 24.8 16.9 0.3 17.2 5.0 11.3 25.4 8.4 15.8 12.2 10.0 28.7 27.1 9.2 3.5 2.3 4.9 12.9 12.4 16.9 7.2 11.0 25.2 28.3 5.1 18.4 11.0 6.1 27.3 33.6 18.6 9.1 36.2 18.4 46.2 40.8 19.0 0.1 16.5 27.3 17.9 11.6 7.2 29.6 22.2 11.0 10.5 53.6 26.9 16.7 1.8 20.9 19.4 4.6 10.1 11.4 11.4 5.1 26.7 22.2 5.7 7.6 1.5 10.6 8.7 10.2 16.1 13.8 12.6 10.0 16.1 13.2 9.7 1.1 6.8 6.3 20.4 15.5 7.1 5.7 5.3 8.0 8.5 5.4 5.3 5.0 4.7 5.0 4.5 6.0 5.2 3.9 0.0 0.5 2.6 9.3 4.2 2.8 8.0 4.6 7.1 4.1 5.3 5.5 1.5 2.2 1.8 4.2 18.6 11.5 4.0 11.7 5.5 80.8 5.8 3.4 3.7 4.9 9.1 14.3 4.2 13.0 5.9 8.6 2.1 0.0 7.1 6.8 5.4 7.6 0.0 13.8 3.2 8.2 3.2 4.0 54.9 8.4 2.5 7.2 6.5 11.9 5.8 12.3 6.0 5.8 3.6 5.8 6.0 4.2 3.3 5.2 12.1 4.8 6.5 6.6 2.3 5.7 92.1 32.3 6.2 4.3 4.4 4.9 7.5 5.5 1.5 IL18 "IGIF, IL-18, IL-1g, IL1F4" ENSG00000150782 "Interleukin 18" Q14116 11 112143253-112164096 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 124.5;skin 1: 149.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 173.1;Basal respiratory cells: 186.4;Basal squamous epithelial cells: 215.1;Kupffer cells: 241.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 25.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 117.9;CAPAN-2: 182.3;HaCaT: 167.0;HBEC3-KT: 125.8;hTCEpi: 188.5;PC-3: 110.2;U-2 OS: 208.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003980, CAB007772" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted to blood" NA Yes 196000 16000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Golgi apparatus" Cytosol "CAB007772: AB_562304, HPA003980: AB_1851670" "unprognostic (2.31e-3)" "unprognostic (3.25e-1)" "prognostic favorable (2.78e-4)" "unprognostic (3.41e-2)" "unprognostic (1.25e-1)" "unprognostic (1.62e-1)" "unprognostic (1.65e-1)" "unprognostic (8.15e-2)" "unprognostic (3.23e-1)" "unprognostic (2.78e-1)" "unprognostic (1.96e-3)" "unprognostic (4.13e-1)" "unprognostic (3.58e-2)" "unprognostic (1.51e-1)" "unprognostic (3.19e-2)" "unprognostic (3.15e-2)" "unprognostic (9.01e-2)" 19.9 6.1 5.3 18.2 5.4 31.6 12.6 5.9 8.6 38.0 7.0 34.1 22.0 2.4 3.3 124.5 8.0 23.0 3.0 5.3 6.0 23.8 9.1 23.0 67.8 7.5 6.2 1.9 17.9 1.3 2.9 6.7 7.4 6.1 29.1 6.9 15.0 3.0 6.0 149.6 22.0 3.6 6.7 29.3 13.4 1.9 5.7 8.0 3.7 2.1 25.7 25.3 77.0 11.3 117.9 40.0 0.0 0.4 0.0 0.0 0.7 2.0 0.0 0.0 0.1 22.4 182.3 0.1 25.7 0.3 3.2 167.0 0.0 125.8 0.0 0.3 1.2 17.5 35.6 9.9 3.9 9.3 32.6 0.2 188.5 0.3 43.5 0.2 0.1 0.1 0.5 0.3 1.6 0.2 0.2 0.9 0.2 31.9 110.2 0.1 0.1 0.4 79.9 24.8 0.1 0.0 78.4 52.1 0.5 1.0 31.0 25.4 0.3 0.4 208.9 1.2 35.9 0.4 0.3 0.6 0.2 67.1 0.2 6.8 8.7 16.0 0.1 10.9 0.0 0.7 0.1 0.0 25.8 0.7 0.0 0.5 9.5 19.6 6.3 5.6 0.0 2.5 5.3 5.4 5.9 8.6 5.3 6.0 7.5 6.2 7.4 6.7 5.7 11.3 1.0 173.1 38.4 0.7 6.0 122.9 33.5 186.4 215.1 2.6 4.6 7.7 1.0 41.5 66.1 9.2 0.0 2.3 10.8 109.9 80.3 24.7 2.4 94.9 1.4 4.6 14.5 26.3 3.8 143.0 3.7 18.8 20.9 32.5 101.2 2.8 8.2 1.9 68.4 0.0 4.6 30.1 57.0 241.0 37.3 1.9 0.0 123.8 3.6 61.8 38.8 2.7 6.2 2.0 1.1 161.4 104.6 4.5 4.6 23.6 67.5 22.3 69.6 39.1 6.6 0.6 3.9 1.5 1.3 152.6 111.2 1.8 9.6 0.3 47.8 90.5 INCENP FLJ31633 ENSG00000149503 "Inner centromere protein" Q9NQS7 11 62123998-62153169 "Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.9" "Cell type enhanced" "Detected in many" "Squamous epithelial cells: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7 "basophil: 1.2;NK-cell: 1.1" "Group enriched" "Detected in many" 7 "granulocytes: 1.2;NK-cells: 1.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013292, HPA051339, HPA070550" Enhanced Supported "Nucleoplasm,Nuclear bodies,Kinetochore,Midbody" Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies, Kinetochore" "Nucleoplasm, Midbody" "CAB013292: AB_2533405, HPA051339: AB_2732566, HPA070550: AB_2686279" "unprognostic (6.31e-2)" "unprognostic (7.29e-2)" "unprognostic (1.65e-3)" "unprognostic (7.35e-2)" "unprognostic (3.18e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.25e-4)" "prognostic unfavorable (8.58e-4)" "unprognostic (1.63e-2)" "unprognostic (4.37e-2)" "prognostic unfavorable (5.76e-5)" "unprognostic (1.74e-2)" "unprognostic (1.08e-3)" "unprognostic (1.17e-3)" "unprognostic (1.22e-1)" "unprognostic (1.36e-1)" "unprognostic (2.78e-3)" 3.1 2.5 2.7 7.5 1.1 20.9 2.8 6.2 3.0 4.6 0.0 4.8 6.8 3.0 8.1 14.0 3.5 2.2 2.8 2.9 0.5 2.4 1.9 3.0 11.6 1.6 0.8 3.8 3.1 3.1 1.5 4.1 1.3 2.5 3.6 3.4 6.1 2.9 4.2 7.9 5.7 3.4 0.1 5.5 4.5 6.4 0.5 17.8 5.1 3.4 8.2 2.8 5.5 1.2 74.3 69.4 51.6 45.5 6.8 8.4 28.1 47.6 21.2 44.4 28.3 37.0 50.7 70.0 36.2 16.0 46.2 72.6 52.2 28.4 31.8 60.5 36.6 45.7 68.0 29.6 2.7 53.5 62.1 4.3 6.5 41.3 23.6 6.8 25.8 50.2 48.8 57.6 25.3 59.7 85.0 43.3 56.2 28.0 34.4 79.3 66.4 53.4 12.0 35.8 40.1 42.2 46.8 30.8 27.9 19.8 48.2 19.4 28.5 41.8 51.9 59.8 50.0 29.7 48.3 75.8 23.5 34.7 50.6 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 2.7 1.1 6.2 3.0 2.9 0.5 1.6 0.8 1.3 0.1 0.5 1.2 1.2 3.2 2.3 1.3 3.4 5.6 0.8 1.0 2.8 2.4 1.1 0.6 1.3 0.0 3.7 0.0 0.0 4.2 4.2 5.4 0.0 1.9 1.0 2.0 2.1 1.5 0.0 10.9 3.3 2.5 7.1 1.9 9.2 2.7 3.8 5.7 0.0 0.7 4.2 0.0 2.5 3.4 0.0 0.9 1.6 0.5 2.8 3.3 3.6 1.0 5.0 1.5 3.1 2.0 1.5 2.2 1.6 1.5 10.9 1.2 1.3 0.3 2.6 2.3 0.0 1.9 4.3 6.5 7.8 15.1 3.3 2.2 3.7 1.9 4.8 1.1 INSR CD220 ENSG00000171105 "Insulin receptor" P06213 19 7112255-7294414 "CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Carbohydrate metabolism" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 9.8;granulocytes: 5.9;monocytes: 12.5" "Cell line enhanced" "Detected in many" "Karpas-707: 54.9;U-266/70: 40.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036302, HPA036303" Uncertain Approved "Vesicles,Plasma membrane" NA Yes 190000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 52: Non-specific - Transcription" Vesicles "Plasma membrane" "HPA036302: AB_2675048, HPA036303: " "unprognostic (4.64e-2)" "unprognostic (2.42e-1)" "unprognostic (9.65e-3)" "unprognostic (9.70e-2)" "unprognostic (1.44e-1)" "unprognostic (1.15e-2)" "unprognostic (2.58e-1)" "unprognostic (5.09e-2)" "unprognostic (1.97e-1)" "unprognostic (3.05e-1)" "unprognostic (9.29e-2)" "unprognostic (1.86e-1)" "unprognostic (6.33e-2)" "unprognostic (3.45e-3)" "unprognostic (2.43e-1)" "unprognostic (2.75e-1)" "unprognostic (8.82e-2)" 13.0 22.6 12.5 2.8 16.8 5.6 13.0 17.3 12.8 14.6 18.8 15.0 10.0 18.4 6.3 4.1 16.9 8.2 26.3 10.0 12.2 21.8 33.0 7.2 2.3 18.3 16.3 39.9 64.2 13.0 16.3 7.4 18.7 15.2 10.4 6.5 16.9 9.9 23.5 11.5 12.2 11.5 14.1 48.2 12.5 5.4 16.6 2.7 14.5 13.3 3.5 12.3 9.2 22.5 6.2 3.2 3.6 5.7 18.8 6.1 11.1 3.5 2.9 1.6 1.6 8.4 7.0 9.0 8.2 6.8 4.0 1.6 8.9 1.4 1.2 0.0 6.4 0.0 2.3 22.6 8.2 4.3 6.7 10.0 4.5 0.2 4.9 4.2 3.8 4.8 9.5 54.9 1.8 3.2 3.1 7.8 3.3 3.8 5.2 29.0 2.1 7.6 0.1 27.8 6.6 5.2 6.5 3.8 3.3 6.4 1.4 21.6 3.6 3.4 2.1 8.2 5.1 40.4 23.9 20.2 4.3 7.3 0.0 2.7 8.6 5.9 0.2 8.8 0.3 0.8 0.3 0.1 9.8 1.1 0.7 0.1 1.9 1.0 12.5 8.2 0.0 1.6 12.5 16.8 17.3 12.8 10.0 12.2 18.3 16.3 18.7 14.1 16.6 22.5 75.6 48.1 34.7 64.9 10.6 64.9 63.6 34.7 8.0 40.4 134.0 76.2 92.1 137.2 83.3 62.5 79.2 17.8 6.7 124.1 15.6 55.1 4.7 26.8 106.8 123.9 163.6 25.0 68.3 78.7 53.7 43.7 20.4 42.1 3.8 168.4 255.2 246.0 9.2 38.7 100.8 97.3 32.6 49.0 31.1 9.0 96.3 35.0 51.6 62.8 24.2 31.6 0.0 62.8 183.5 50.7 68.8 245.3 21.8 107.9 122.9 114.1 65.3 23.6 59.2 37.6 44.2 5.2 3.6 3.2 68.8 38.3 4.7 81.4 65.2 130.0 IQGAP3 ENSG00000183856 "IQ motif containing GTPase activating protein 3" Q86VI3 1 156525405-156572604 "Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.5" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 11.2;Late spermatids: 26.6;Undifferentiated cells: 7.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "HPA030142, HPA030143" Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA030142: AB_10600108, HPA030143: AB_10601104" "unprognostic (9.99e-3)" "unprognostic (5.24e-2)" "unprognostic (3.26e-1)" "unprognostic (1.55e-3)" "unprognostic (1.52e-1)" "unprognostic (4.69e-3)" "prognostic unfavorable (8.94e-6)" "unprognostic (1.86e-3)" "unprognostic (1.72e-1)" "unprognostic (1.98e-1)" "unprognostic (6.35e-3)" "unprognostic (1.03e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.46e-2)" "unprognostic (1.53e-1)" "unprognostic (6.30e-2)" "unprognostic (6.81e-2)" 0.7 0.7 0.2 2.2 0.4 15.5 0.6 0.0 0.6 1.1 0.2 4.1 6.6 0.5 1.1 5.2 0.2 0.7 0.4 0.5 0.1 0.6 0.6 1.6 1.6 0.9 0.4 0.1 0.2 0.1 0.1 2.8 0.9 0.4 5.0 0.0 1.0 0.1 0.3 3.7 5.7 2.9 0.0 0.8 4.6 3.8 0.6 3.4 0.2 0.0 2.2 0.9 2.1 0.4 59.2 28.4 25.6 18.1 1.6 4.0 12.4 43.1 28.3 41.0 36.6 32.4 52.5 5.2 15.6 25.2 21.6 54.6 17.5 22.1 36.3 0.1 15.7 7.8 62.6 16.1 0.2 9.7 0.1 1.2 2.5 34.3 50.0 10.0 24.1 12.5 16.1 8.1 30.2 31.2 5.7 13.7 18.6 57.7 28.0 18.9 28.8 6.1 10.4 20.3 16.3 25.2 38.7 44.9 14.9 29.8 35.8 25.6 16.8 36.8 43.7 30.4 51.4 4.0 2.1 2.4 12.4 15.1 42.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.2 0.4 0.0 0.6 0.5 0.1 0.9 0.4 0.9 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.4 1.3 0.1 0.4 0.6 0.0 1.4 1.3 1.0 2.8 0.1 0.0 0.0 2.2 0.1 3.9 0.0 0.3 6.5 0.5 0.7 0.6 1.2 6.5 0.7 0.0 3.6 0.9 11.2 1.4 0.0 4.4 2.5 0.4 3.9 0.0 0.2 3.7 0.0 1.3 6.1 26.6 0.3 1.9 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.5 0.4 0.8 0.4 0.0 0.0 0.0 0.0 1.4 6.4 2.6 3.6 1.0 0.8 0.2 0.3 7.4 0.4 IRF2BPL "C14orf4, EAP1, KIAA1865" ENSG00000119669 "Interferon regulatory factor 2 binding protein like" Q9H1B7 14 77024543-77028708 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050862, HPA061333" Approved Enhanced Nucleoplasm NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA050862: AB_2681258, HPA061333: AB_2684481" "unprognostic (5.58e-2)" "unprognostic (6.48e-2)" "unprognostic (1.99e-3)" "prognostic unfavorable (5.52e-4)" "unprognostic (8.78e-3)" "unprognostic (1.57e-2)" "unprognostic (2.70e-1)" "unprognostic (1.81e-1)" "unprognostic (5.74e-2)" "unprognostic (2.53e-2)" "unprognostic (2.51e-3)" "unprognostic (5.39e-2)" "unprognostic (1.03e-3)" "unprognostic (2.55e-1)" "unprognostic (9.33e-2)" "unprognostic (1.14e-1)" "unprognostic (1.58e-2)" 26.1 25.3 12.2 9.2 13.9 5.6 28.5 13.4 12.0 20.1 12.8 32.4 6.9 25.8 5.1 13.3 33.7 6.5 22.6 14.1 21.1 28.7 19.1 20.9 6.2 15.2 14.8 32.4 17.5 19.8 22.6 7.9 10.9 18.4 3.3 7.3 19.2 10.1 16.8 25.2 15.1 8.0 12.6 19.0 18.8 13.5 19.0 9.7 18.7 4.2 3.3 26.4 18.2 9.4 15.4 13.2 32.2 36.3 9.6 8.8 45.8 15.9 13.0 4.4 5.9 6.2 24.8 5.4 11.3 13.6 12.4 23.6 5.6 11.8 3.7 25.8 19.1 6.9 13.0 8.5 12.5 1.9 29.7 11.8 9.1 7.8 6.8 34.8 6.0 10.9 10.4 59.4 5.7 42.2 21.0 14.5 14.5 6.6 68.2 4.4 9.1 13.0 15.6 22.4 24.9 36.0 22.5 23.2 42.5 8.6 16.1 3.4 10.4 20.2 19.5 6.8 10.3 22.9 26.3 9.0 31.3 4.7 25.8 1.7 1.4 1.3 2.8 1.9 2.7 1.4 2.5 2.6 1.3 1.6 2.0 2.3 9.0 5.9 2.3 10.7 2.6 0.8 12.2 13.9 13.4 12.0 14.1 21.1 15.2 14.8 10.9 12.6 19.0 9.4 71.4 22.4 14.3 5.9 40.2 73.7 32.5 22.5 115.5 57.1 54.6 41.5 19.5 32.9 11.6 64.4 29.2 22.8 58.9 10.8 37.2 19.6 1.3 25.3 26.0 44.0 47.6 10.8 8.2 19.0 49.7 47.8 12.2 25.6 26.6 15.2 55.6 60.5 33.3 10.1 8.6 14.7 16.2 54.7 78.9 4.0 30.1 26.6 35.6 9.4 10.0 57.8 38.1 8.5 4.8 17.8 7.0 34.3 21.1 30.0 6.7 23.1 13.8 10.4 39.5 56.4 83.2 1.6 50.5 54.2 50.6 46.0 39.0 27.5 12.8 20.6 ITPR3 IP3R3 ENSG00000096433 "Inositol 1,4,5-trisphosphate receptor type 3" Q14573 6 33620365-33696574 "Human disease related genes, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 123.0;Gastric mucus-secreting cells: 127.4;Late spermatids: 220.4;Pancreatic endocrine cells: 89.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 164.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA003915, HPA064704" Approved Uncertain Vesicles No Yes "Cluster 44: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA003915: AB_1851845, HPA064704: " "unprognostic (2.57e-1)" "unprognostic (2.81e-2)" "unprognostic (1.52e-2)" "unprognostic (2.30e-1)" "unprognostic (5.40e-2)" "unprognostic (1.24e-1)" "unprognostic (2.08e-2)" "unprognostic (6.14e-2)" "unprognostic (3.35e-1)" "unprognostic (3.08e-2)" "unprognostic (4.14e-3)" "unprognostic (1.88e-1)" "unprognostic (6.44e-3)" "unprognostic (5.01e-2)" "unprognostic (1.74e-1)" "unprognostic (8.89e-2)" "unprognostic (2.43e-2)" 16.3 11.4 5.5 17.0 5.0 6.1 14.6 3.8 5.3 18.0 3.7 26.2 29.1 8.5 13.1 18.1 14.0 15.3 15.0 3.8 3.9 16.4 2.2 30.6 20.4 5.6 5.0 13.5 11.3 2.8 7.4 4.3 5.2 13.9 18.4 0.8 18.5 11.2 4.5 58.9 35.1 4.7 4.7 39.8 41.5 15.4 7.0 14.3 54.0 5.1 21.0 12.1 24.0 3.9 73.7 34.0 6.3 0.3 6.2 19.3 40.9 24.8 62.8 30.5 27.4 46.7 55.9 62.6 26.1 17.9 76.1 70.9 28.6 66.7 15.7 36.8 24.0 0.1 102.6 52.0 14.1 11.3 7.9 14.0 59.2 76.7 164.7 66.5 52.1 24.5 25.0 19.7 33.3 35.0 19.0 6.4 6.2 55.8 49.4 29.0 0.1 37.1 107.6 50.9 57.3 2.1 42.8 61.6 60.2 6.9 21.2 5.9 71.8 41.1 20.1 53.1 55.2 13.5 14.3 29.4 32.8 16.6 24.1 0.8 0.0 0.0 0.8 0.0 0.6 0.4 0.4 0.5 0.0 0.6 0.4 0.5 0.0 0.0 0.0 0.0 0.7 0.2 5.5 5.0 3.8 5.3 3.8 3.9 5.6 5.0 5.2 4.7 7.0 3.9 12.4 48.1 58.9 0.3 13.5 26.5 10.9 27.9 18.2 1.5 9.3 9.9 2.7 12.8 20.2 31.3 0.0 0.3 10.9 52.9 0.0 28.4 123.0 19.1 9.1 18.2 23.9 6.6 1.1 30.2 6.3 9.2 127.4 43.1 0.0 0.2 12.5 0.4 0.5 0.0 1.6 41.6 10.2 0.6 6.9 220.4 23.3 2.6 12.4 23.4 3.2 0.4 4.1 0.5 0.4 89.7 41.6 13.9 18.7 20.5 45.9 0.2 12.1 1.2 6.6 3.9 3.3 1.6 3.2 14.5 25.4 0.5 13.1 5.8 35.6 20.7 KANK2 "ANKRD25, KIAA1518, MXRA3" ENSG00000197256 "KN motif and ankyrin repeat domains 2" Q63ZY3 19 11164270-11197791 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 402.5;Endometrial stromal cells: 149.6;Leydig cells: 126.2;Peritubular cells: 225.7;Smooth muscle cells: 131.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "ASC diff: 327.8;ASC TERT1: 365.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015643 Approved Approved Nucleoplasm,Cytosol NA Yes "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm Cytosol "HPA015643: AB_1844839" "unprognostic (2.37e-1)" "unprognostic (8.03e-2)" "unprognostic (1.15e-2)" "unprognostic (1.30e-1)" "unprognostic (1.00e-1)" "unprognostic (3.23e-3)" "unprognostic (1.54e-1)" "unprognostic (8.63e-2)" "unprognostic (8.98e-2)" "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (8.73e-5)" "unprognostic (4.01e-2)" "unprognostic (1.37e-1)" "unprognostic (1.13e-1)" "unprognostic (1.48e-2)" 150.2 55.5 25.7 50.5 27.2 17.9 97.7 22.8 25.6 275.3 24.5 413.2 36.8 376.9 64.6 139.1 222.1 125.0 200.5 20.0 27.9 54.1 51.3 134.5 20.7 29.5 26.5 213.9 35.4 14.3 29.8 62.3 29.0 140.5 58.7 19.0 39.3 173.6 56.9 49.7 108.0 277.7 23.8 57.8 123.7 25.0 29.5 15.7 71.7 51.1 12.4 255.2 148.5 22.6 42.4 91.1 28.3 30.3 327.8 365.1 20.2 188.9 161.0 92.1 76.2 36.3 27.0 177.2 88.1 234.3 59.6 40.0 25.6 13.7 61.3 9.3 18.4 77.2 105.6 37.5 123.9 11.8 21.4 158.7 20.1 67.3 9.0 237.2 37.8 5.5 51.5 14.3 143.6 75.7 2.3 9.9 31.4 27.5 95.1 59.7 234.8 42.2 65.4 22.7 16.6 51.7 188.2 16.4 22.4 32.7 25.1 41.2 139.1 131.5 52.6 170.1 75.2 13.7 32.9 61.3 111.0 66.3 136.4 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 25.7 27.2 22.8 25.6 20.0 27.9 29.5 26.5 29.0 23.8 29.5 22.6 34.1 57.7 28.3 7.8 1.3 6.2 5.5 5.2 2.2 2.0 5.2 7.1 402.5 27.1 12.0 20.2 20.9 6.9 0.6 2.5 3.9 8.1 2.4 12.7 149.6 41.2 0.0 76.2 0.9 4.4 4.9 69.2 13.3 11.9 7.6 7.7 32.5 28.2 22.5 0.0 4.1 2.6 4.1 10.6 15.1 3.8 126.2 6.3 8.8 42.2 0.5 34.9 4.1 1.0 1.4 11.9 1.2 225.7 0.8 6.7 1.6 3.7 8.0 23.4 92.1 79.2 131.0 1.8 7.2 2.8 7.7 2.3 2.3 7.7 5.2 8.4 KBTBD2 "BKLHD1, DKFZP566C134" ENSG00000170852 "Kelch repeat and BTB domain containing 2" Q8IY47 7 32868172-32894131 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021133 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA Yes "Cluster 5: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nucleoli fibrillar center" "HPA021133: AB_1852093" "unprognostic (1.01e-1)" "prognostic unfavorable (1.89e-4)" "unprognostic (3.17e-2)" "unprognostic (9.19e-2)" "unprognostic (1.16e-1)" "unprognostic (3.70e-2)" "prognostic unfavorable (5.69e-4)" "unprognostic (3.96e-3)" "unprognostic (1.05e-1)" "unprognostic (2.61e-1)" "unprognostic (2.80e-3)" "unprognostic (5.05e-1)" "unprognostic (6.79e-3)" "unprognostic (3.81e-3)" "unprognostic (1.42e-2)" "unprognostic (8.69e-2)" "unprognostic (2.96e-1)" 26.4 16.4 23.0 21.7 25.2 54.6 20.9 27.3 24.9 17.2 21.4 16.9 15.9 20.8 10.7 16.1 15.6 25.2 20.3 21.0 24.8 15.3 21.5 22.5 25.6 27.2 25.8 16.4 11.8 17.1 15.0 25.8 27.2 16.3 19.6 25.9 14.4 15.0 57.6 16.3 17.6 23.6 26.3 27.0 14.8 18.1 26.5 30.5 18.6 40.3 24.0 22.0 17.3 28.8 38.3 18.8 47.5 23.5 28.1 28.0 17.1 33.4 33.9 31.2 37.6 18.7 28.6 31.9 22.6 34.7 52.3 27.5 24.5 26.2 39.2 12.6 17.6 27.1 30.6 24.4 28.9 29.3 34.2 30.1 26.9 34.0 32.9 28.9 34.9 28.6 50.3 46.2 46.4 31.4 24.3 47.9 38.6 26.5 17.7 23.4 41.6 26.7 27.6 22.3 24.9 46.4 21.5 29.1 38.6 39.6 20.7 49.5 30.5 29.6 38.7 28.3 46.5 37.5 39.3 57.6 28.8 34.9 77.0 14.5 6.4 21.4 10.9 12.2 9.2 7.1 5.4 9.7 5.6 9.8 4.2 6.9 39.2 10.7 14.6 2.9 7.6 4.1 23.0 25.2 27.3 24.9 21.0 24.8 27.2 25.8 27.2 26.3 26.5 28.8 67.2 28.9 23.9 24.5 27.0 40.4 15.7 13.4 44.3 14.6 20.4 15.6 18.4 20.0 22.1 1.8 10.4 6.9 41.4 18.1 0.0 11.8 7.7 21.6 23.1 48.7 14.9 25.2 21.0 12.2 8.7 22.2 17.9 33.8 43.7 20.4 36.8 14.6 13.3 8.4 20.5 14.0 4.1 24.6 23.1 6.2 13.1 32.5 24.9 34.7 13.0 8.7 15.5 29.7 36.8 16.8 10.3 6.0 25.2 17.1 10.5 5.1 7.3 8.9 19.7 26.4 21.1 19.1 8.8 25.9 36.1 7.5 28.4 10.8 11.4 18.5 KDM5B "CT31, JARID1B, PLU-1, PPP1R98, RBBP2H1A" ENSG00000117139 "Lysine demethylase 5B" Q9UGL1 1 202724495-202808487 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase, Repressor" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 62.3" "Cell type enhanced" "Detected in all" "Late spermatids: 243.6;Spermatocytes: 390.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027179, HPA053723, CAB068193" Enhanced Supported Nucleoplasm,Cytosol NA Yes "Cluster 10: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "CAB068193: AB_2665696, HPA027179: AB_1851987, HPA053723: AB_2682241" "unprognostic (1.19e-1)" "unprognostic (1.74e-2)" "unprognostic (1.03e-1)" "unprognostic (4.67e-2)" "unprognostic (1.92e-2)" "unprognostic (2.31e-1)" "unprognostic (3.49e-3)" "unprognostic (3.02e-2)" "unprognostic (3.23e-2)" "unprognostic (6.12e-2)" "unprognostic (1.61e-2)" "unprognostic (4.79e-2)" "unprognostic (8.25e-3)" "unprognostic (2.56e-2)" "unprognostic (1.61e-1)" "unprognostic (5.56e-2)" "unprognostic (4.13e-1)" 9.1 7.7 1.5 2.6 2.2 14.1 9.9 5.8 4.8 14.7 7.9 10.6 2.1 12.6 3.3 21.0 9.9 2.9 6.0 4.6 1.5 6.2 4.6 10.8 2.2 0.8 0.4 12.8 8.3 2.6 6.9 4.7 0.2 10.6 2.2 17.8 12.5 2.4 4.7 24.3 8.6 3.1 1.0 7.4 8.7 62.3 1.2 4.1 8.4 0.8 2.1 10.9 15.7 2.3 9.9 2.4 14.0 9.8 7.2 6.6 23.7 6.2 9.4 6.2 6.4 2.2 8.8 0.1 5.7 7.9 2.3 11.8 9.0 8.3 5.4 0.5 12.8 7.7 2.4 1.9 5.5 17.7 8.9 9.4 12.1 7.0 7.2 10.1 11.7 7.3 20.9 0.3 4.9 6.3 5.8 16.4 21.9 4.3 28.0 18.7 0.1 0.4 6.5 10.7 10.7 23.4 14.7 7.9 8.7 15.7 16.6 10.5 12.8 8.2 5.8 1.4 5.2 2.3 1.1 8.2 6.0 5.5 4.1 44.6 6.4 19.6 7.7 4.8 4.6 10.9 8.9 4.3 4.2 17.4 9.6 6.0 34.4 12.9 10.4 6.6 7.2 3.9 1.5 2.2 5.8 4.8 4.6 1.5 0.8 0.4 0.2 1.0 1.2 2.3 24.5 89.8 38.5 46.7 22.2 64.4 34.8 53.0 84.2 35.5 57.1 50.0 9.5 11.5 53.6 16.5 62.6 41.8 12.4 23.7 5.9 47.6 191.6 65.2 71.8 31.9 43.6 50.2 75.8 22.3 34.3 42.7 47.9 69.5 27.1 28.6 17.2 10.9 7.7 15.2 53.5 38.1 44.7 15.1 21.9 243.6 36.4 15.5 26.6 40.3 11.3 69.8 10.3 39.7 42.5 45.4 21.8 32.7 25.8 43.1 15.2 8.2 61.9 138.6 32.9 22.8 40.2 390.9 71.0 95.9 116.2 82.4 21.2 61.5 30.2 55.6 KIF11 "Eg5, HKSP, KNSL1, TRIP5" ENSG00000138160 "Kinesin family member 11" P52732 10 92574105-92655395 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.4;lymphoid tissue: 37.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 39.1;Granulosa cells: 20.7;Spermatocytes: 38.0;Spermatogonia: 23.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA006916, HPA010093, HPA010568, CAB017617" Enhanced Supported "Mitotic spindle,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Mitotic spindle" "CAB017617: AB_2131098, HPA006916: AB_1848033, HPA010093: AB_2668281, HPA010568: AB_1848034" "unprognostic (1.53e-1)" "unprognostic (1.11e-2)" "unprognostic (1.59e-2)" "unprognostic (3.35e-2)" "unprognostic (2.12e-1)" "unprognostic (7.82e-2)" "prognostic unfavorable (8.19e-7)" "prognostic unfavorable (3.27e-4)" "unprognostic (1.24e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.30e-4)" "unprognostic (6.59e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.35e-3)" "unprognostic (7.23e-2)" "unprognostic (9.08e-2)" "unprognostic (2.01e-1)" 1.1 0.7 0.5 8.5 0.7 19.4 2.5 0.4 0.6 1.4 0.5 6.3 5.5 1.8 1.0 6.7 1.0 1.2 0.6 0.5 0.5 1.0 1.1 1.3 17.5 0.6 0.6 0.6 0.5 0.7 0.3 3.9 0.6 1.0 7.4 0.8 1.3 0.7 0.2 6.0 5.3 2.5 0.5 2.9 3.9 11.6 0.4 37.9 1.6 0.3 18.5 2.3 2.3 0.6 103.1 45.2 100.6 94.5 7.3 10.5 24.2 72.6 62.8 78.8 78.1 39.6 67.2 111.1 36.5 34.4 32.9 72.0 72.1 36.5 92.4 68.3 41.3 70.5 41.4 42.4 1.4 116.0 63.0 3.6 3.3 61.4 55.9 18.3 50.0 46.1 51.2 126.4 61.1 41.4 99.3 65.8 40.3 42.5 30.7 106.6 98.8 40.2 21.0 30.1 30.0 42.9 56.4 25.9 29.2 34.1 67.9 37.6 28.6 35.7 51.3 37.1 96.9 35.4 58.3 113.4 29.5 82.3 50.3 0.8 0.0 0.1 0.0 0.3 0.3 0.6 0.4 0.4 0.2 0.1 0.1 0.2 0.2 1.0 0.1 0.1 1.1 0.2 0.5 0.7 0.4 0.6 0.5 0.5 0.6 0.6 0.6 0.5 0.4 0.6 0.4 0.0 2.0 1.3 3.5 2.9 1.1 1.6 3.4 1.0 1.8 1.8 1.7 1.5 2.5 1.8 0.0 6.7 2.3 2.9 1.9 0.5 16.3 3.4 4.3 2.0 0.0 39.1 2.1 0.6 11.4 4.7 9.2 4.9 0.0 20.7 2.2 0.4 8.2 0.0 1.8 4.3 4.1 4.6 3.4 4.4 0.9 4.0 0.0 0.0 1.0 0.7 2.1 2.5 1.1 0.2 0.4 0.7 15.2 0.8 0.5 0.6 3.7 0.4 0.0 1.7 3.7 38.0 23.4 12.6 3.3 1.5 4.5 2.5 8.0 1.7 KIF14 KIAA0042 ENSG00000118193 "Kinesin family member 14" Q15058 1 200551497-200620751 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Ciliopathy, Disease variant, Meckel syndrome, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.5;lymphoid tissue: 10.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 27.1;Granulosa cells: 13.2;Spermatocytes: 22.8;Spermatogonia: 16.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038061, HPA058220" Uncertain Supported "Midbody ring,Cytosol" Yes Yes "Cluster 18: Basophils - Vesicular transport" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Midbody ring" "HPA038061: AB_10669515, HPA058220: AB_2683642" "unprognostic (1.84e-1)" "unprognostic (7.15e-2)" "unprognostic (2.00e-2)" "unprognostic (1.87e-2)" "unprognostic (2.74e-1)" "unprognostic (1.51e-1)" "unprognostic (1.18e-3)" "prognostic unfavorable (8.64e-4)" "unprognostic (8.47e-3)" "unprognostic (1.02e-1)" "unprognostic (2.54e-5)" "unprognostic (2.31e-2)" "unprognostic (0.00e+0)" "unprognostic (6.28e-3)" "unprognostic (3.31e-1)" "unprognostic (8.14e-2)" "unprognostic (7.44e-2)" 0.2 0.2 0.1 2.0 0.0 6.5 0.3 0.2 0.3 0.2 0.1 0.9 1.2 0.3 0.0 1.0 0.0 0.2 0.0 0.1 0.1 0.0 0.3 0.2 3.2 0.1 0.2 0.0 0.0 0.0 0.0 0.9 0.1 0.0 1.2 0.1 0.1 0.0 0.0 1.0 1.1 0.6 0.0 0.6 0.6 2.5 0.1 10.9 0.1 0.0 3.2 0.4 0.3 0.1 29.7 17.3 26.8 15.0 0.8 3.0 14.8 20.0 11.7 18.7 16.8 10.5 15.1 18.0 7.0 9.6 11.6 23.0 21.6 13.3 26.7 22.1 11.3 28.8 24.8 10.3 0.1 45.5 15.7 0.6 0.6 20.9 17.8 4.0 13.5 26.3 44.0 22.6 23.5 12.1 26.9 14.2 22.6 8.7 15.0 24.3 35.4 22.8 6.3 8.3 12.7 14.0 28.3 9.5 11.0 19.8 12.9 11.6 11.1 14.7 17.3 16.2 35.3 8.2 8.9 25.8 8.6 24.0 30.5 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.3 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 1.0 0.0 0.0 0.0 1.9 2.4 1.0 1.1 0.6 2.3 1.5 1.9 0.8 0.0 0.9 0.0 2.1 4.2 0.6 2.5 0.0 0.2 4.1 3.7 2.2 1.6 0.0 27.1 1.1 0.0 7.7 3.3 10.2 5.0 2.5 13.2 2.5 0.9 5.4 0.0 0.9 5.2 0.0 2.9 1.9 2.5 0.6 2.3 0.0 0.0 0.4 0.5 0.0 0.5 0.8 0.3 0.0 0.7 11.3 1.2 0.2 0.1 1.4 0.8 6.6 1.4 2.1 22.8 16.3 8.3 0.9 1.4 2.3 0.7 4.3 1.9 KIF18A "DKFZP434G2226, PPP1R99" ENSG00000121621 "Kinesin family member 18A" Q8NI77 11 28020619-28108156 "Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 8.2;lymphoid tissue: 9.6;testis: 13.7" "Cell type enhanced" "Detected in many" "Early spermatids: 43.1;Spermatocytes: 78.7;Spermatogonia: 28.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 4.1;memory B-cell: 1.0;NK-cell: 1.4;T-reg: 1.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA039312, HPA039484" Approved Supported "Microtubules,Cytokinetic bridge" Yes Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Microtubules, Cytokinetic bridge" "HPA039312: AB_10794087, HPA039484: AB_10795252" "unprognostic (3.79e-1)" "unprognostic (2.63e-1)" "unprognostic (7.09e-3)" "unprognostic (3.80e-2)" "unprognostic (6.56e-2)" "unprognostic (1.39e-1)" "unprognostic (1.34e-7)" "unprognostic (2.43e-3)" "unprognostic (2.04e-3)" "unprognostic (1.23e-2)" "unprognostic (1.72e-4)" "unprognostic (4.41e-2)" "unprognostic (0.00e+0)" "unprognostic (7.88e-3)" "unprognostic (1.67e-1)" "unprognostic (1.43e-1)" "unprognostic (2.50e-1)" 0.2 0.1 0.0 1.9 0.1 8.2 0.7 0.0 0.1 0.7 0.1 1.6 1.5 0.5 0.3 1.4 0.3 0.5 0.0 0.1 0.1 0.3 0.3 1.0 4.7 0.1 0.1 0.1 0.1 0.1 0.1 1.5 0.1 0.3 2.0 0.6 0.3 0.4 0.2 1.2 1.4 0.8 0.1 0.7 0.6 13.7 0.2 9.6 1.1 0.1 4.6 0.7 0.5 0.1 27.9 27.4 27.2 19.0 0.9 3.7 9.1 28.3 13.2 44.2 46.0 9.2 11.0 23.3 10.0 14.7 24.1 27.2 23.4 11.1 61.4 23.4 14.2 15.2 17.8 11.8 2.1 22.6 13.4 6.8 1.4 15.5 18.1 7.8 17.2 19.0 24.6 20.0 25.2 14.8 23.1 16.7 13.4 18.0 11.1 17.8 65.0 11.6 12.5 8.0 16.3 12.6 23.7 11.1 7.8 16.5 23.8 6.9 10.1 35.0 27.2 33.2 37.4 7.9 19.8 23.4 21.0 16.5 25.2 4.1 0.0 0.3 0.1 0.2 0.3 1.0 0.4 0.2 0.3 0.4 0.3 0.1 0.0 1.4 0.0 0.3 1.1 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 1.2 3.2 0.0 0.0 4.7 2.3 1.3 1.4 1.2 0.3 1.3 2.9 0.5 0.0 2.2 0.0 6.2 4.6 2.8 1.9 0.0 0.6 43.1 3.4 2.5 1.1 1.8 15.4 0.2 0.9 7.1 5.4 1.5 3.4 4.5 9.7 1.4 0.0 2.2 0.0 0.1 1.9 0.0 1.6 1.4 8.7 0.6 1.4 0.0 1.0 1.1 0.7 1.0 0.5 0.9 0.5 0.1 0.4 5.1 0.2 0.2 0.6 1.7 1.9 0.0 2.5 1.9 78.7 28.3 4.3 1.0 1.6 3.9 2.7 3.6 0.5 KIF18B ENSG00000186185 "Kinesin family member 18B" Q86Y91 17 44924709-44947773 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 12.7;lymphoid tissue: 14.4" "Cell type enhanced" "Detected in some" "Erythroid cells: 9.0;Extravillous trophoblasts: 3.8;Granulosa cells: 5.9;Oligodendrocyte precursor cells: 7.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in single" "white matter: 1.4" "Low region specificity" "Detected in many" HPA024205 Enhanced Supported "Nucleoplasm,Nuclear bodies,Microtubule ends,Cytosol" Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Microtubule ends" "Nuclear bodies, Cytosol" "HPA024205: AB_1852472" "unprognostic (1.88e-1)" "unprognostic (9.92e-2)" "unprognostic (4.61e-2)" "unprognostic (1.13e-2)" "unprognostic (4.17e-1)" "unprognostic (7.27e-3)" "prognostic unfavorable (2.44e-6)" "unprognostic (3.34e-3)" "prognostic unfavorable (6.90e-4)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.16e-4)" "unprognostic (8.18e-2)" "unprognostic (0.00e+0)" "unprognostic (4.69e-3)" "unprognostic (1.93e-1)" "unprognostic (3.08e-1)" "unprognostic (1.68e-2)" 0.4 0.4 0.3 3.8 0.4 12.7 0.2 0.7 0.3 0.9 0.3 2.0 2.7 0.4 0.0 5.1 0.2 0.4 0.3 0.3 0.4 0.2 0.4 0.8 5.7 0.5 1.1 0.1 0.1 0.0 0.1 1.9 0.6 0.2 1.7 0.1 0.7 0.0 0.4 3.0 2.5 1.1 0.3 2.9 1.5 2.9 0.6 14.4 0.2 0.0 4.7 0.6 1.6 0.5 31.5 41.7 35.3 32.8 0.8 3.0 28.1 25.8 10.3 34.6 26.9 34.0 27.4 28.3 10.9 10.8 21.5 34.0 25.1 11.3 17.9 56.6 36.4 35.4 51.7 22.1 0.0 30.0 30.2 0.7 0.6 29.7 12.2 4.7 17.9 29.2 28.1 48.0 18.2 25.9 60.0 31.1 25.4 30.4 28.9 43.5 51.8 19.2 5.8 16.7 26.2 24.7 18.0 16.1 9.8 17.0 30.2 21.6 11.2 49.9 48.0 28.8 56.8 15.1 15.7 34.4 16.3 22.9 33.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.3 0.4 0.7 0.3 0.3 0.4 0.5 1.1 0.6 0.3 0.6 0.5 0.1 0.0 0.0 0.0 0.9 0.4 0.1 0.2 0.0 0.5 0.5 0.4 2.6 0.0 0.0 0.0 0.0 2.4 0.4 1.9 0.0 0.0 0.0 0.3 0.8 0.6 0.0 9.0 0.3 0.0 3.8 1.4 1.5 0.5 0.0 5.9 0.4 0.3 2.3 0.0 0.3 1.6 0.0 2.2 1.1 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 7.1 0.1 0.1 0.0 0.0 2.1 0.2 0.3 0.0 0.0 0.3 0.0 0.2 0.8 1.1 2.9 2.5 0.4 0.8 1.3 0.3 3.2 0.3 KIF20A RAB6KIFL ENSG00000112984 "Kinesin family member 20A" O95235 5 138178719-138187723 "Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.1;lymphoid tissue: 24.6;testis: 11.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 11.0;Erythroid cells: 24.6;Extravillous trophoblasts: 13.1;Granulosa cells: 11.1;Spermatocytes: 21.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "NK-cell: 6.6;T-reg: 2.5" "Group enriched" "Detected in many" 46 "NK-cells: 6.6;T-cells: 2.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA036909, HPA036910" Approved Uncertain "Nucleoplasm,Cytokinetic bridge" Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytokinetic bridge" "HPA036909: AB_10670245, HPA036910: AB_10671716" "unprognostic (7.50e-2)" "unprognostic (2.43e-1)" "unprognostic (1.39e-3)" "unprognostic (1.21e-2)" "unprognostic (3.47e-2)" "unprognostic (2.60e-2)" "prognostic unfavorable (2.14e-12)" "prognostic unfavorable (6.79e-4)" "unprognostic (2.86e-2)" "unprognostic (3.16e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (9.73e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (9.05e-2)" "unprognostic (2.61e-1)" "unprognostic (1.09e-1)" "unprognostic (3.16e-1)" 0.7 0.8 0.0 4.5 0.1 14.1 1.3 0.1 0.1 1.0 0.1 3.3 3.5 1.4 0.0 6.6 0.4 0.8 0.5 0.0 0.1 0.4 0.9 0.9 8.6 0.1 0.2 0.2 0.2 0.1 0.0 5.4 0.1 0.2 5.1 0.0 1.0 0.1 0.1 4.4 2.8 5.8 0.0 1.9 2.1 11.7 0.5 24.6 0.5 0.1 13.1 1.6 2.0 0.1 87.8 59.5 127.8 84.4 6.7 12.3 53.9 75.0 68.9 162.3 121.4 111.9 80.5 38.8 39.2 96.5 60.6 85.9 121.7 142.5 160.9 56.4 57.4 57.2 101.1 70.7 0.3 28.2 25.1 4.8 2.3 86.2 49.5 27.1 106.7 53.9 24.4 70.4 113.9 81.5 47.6 26.7 80.6 51.8 63.7 51.2 128.5 39.5 43.9 42.3 37.8 37.5 144.1 47.9 30.9 161.6 60.8 28.5 51.1 41.6 60.5 38.0 126.4 36.0 37.5 42.0 26.7 81.1 82.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 2.5 0.3 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.5 0.1 0.3 0.0 1.7 0.0 0.8 0.4 0.4 2.9 0.0 0.0 1.1 1.3 0.3 0.0 0.7 0.0 0.0 11.0 0.1 2.8 0.0 0.1 1.0 1.0 1.9 1.7 0.0 24.6 0.0 0.0 13.1 3.1 2.6 1.3 4.5 11.1 3.3 0.4 6.1 0.0 0.0 1.6 6.1 2.2 0.4 2.0 0.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.4 3.0 0.3 1.2 0.0 0.9 0.0 0.0 0.5 4.4 21.7 7.5 5.3 0.4 1.0 0.7 0.8 3.4 0.6 KIF20B "CT90, KRMP1, MPHOSPH1, MPP1" ENSG00000138182 "Kinesin family member 20B" Q96Q89 10 89701590-89774939 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.2;lymphoid tissue: 9.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 89.2;Spermatocytes: 165.4;Spermatogonia: 96.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA050214 Supported Supported "Nucleoplasm,Cytokinetic bridge,Midbody,Cytosol" Yes Yes "Cluster 6: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytokinetic bridge" "Midbody, Cytosol" "HPA050214: AB_2681053" "unprognostic (2.13e-1)" "unprognostic (3.01e-2)" "unprognostic (1.72e-2)" "unprognostic (3.20e-2)" "unprognostic (2.65e-1)" "unprognostic (7.39e-2)" "unprognostic (8.95e-5)" "unprognostic (3.32e-3)" "unprognostic (2.01e-2)" "unprognostic (8.14e-2)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.62e-2)" "prognostic unfavorable (3.06e-6)" "unprognostic (4.22e-3)" "unprognostic (2.70e-1)" "unprognostic (2.51e-2)" "unprognostic (6.43e-2)" 1.3 0.7 0.3 4.5 1.0 10.2 2.5 2.4 0.4 1.5 0.1 3.2 3.6 2.3 0.4 3.3 1.2 1.3 0.9 0.3 0.3 1.3 1.3 1.5 8.0 0.5 0.3 2.7 0.7 1.1 0.2 2.4 0.6 1.3 4.0 1.1 1.0 0.9 0.4 2.5 3.4 2.2 0.4 3.3 2.5 6.9 0.6 9.8 1.8 0.7 7.5 1.6 0.7 0.6 84.8 17.0 24.3 21.7 4.7 8.0 20.2 33.8 30.9 34.8 36.3 22.6 38.1 32.5 10.4 17.3 13.0 41.8 27.3 18.9 46.4 39.5 18.6 33.1 30.5 19.5 1.4 57.1 26.3 3.4 2.8 33.7 33.9 12.2 22.8 17.0 32.2 36.5 31.3 14.6 33.6 10.8 25.0 13.8 16.1 23.1 47.8 14.3 10.7 11.2 7.7 13.9 24.4 11.0 12.2 17.3 28.5 16.3 17.9 22.2 22.1 29.1 55.3 10.1 29.5 43.2 21.1 49.4 16.8 13.1 2.4 4.2 5.5 4.1 6.8 13.0 7.4 6.1 1.3 16.0 8.6 8.0 0.2 3.0 4.5 5.2 9.5 2.2 0.3 1.0 2.4 0.4 0.3 0.3 0.5 0.3 0.6 0.4 0.6 0.6 11.5 3.2 13.5 2.3 36.4 17.7 6.2 20.8 6.8 14.3 8.3 8.5 8.7 1.5 10.7 0.0 10.4 21.4 32.3 8.8 3.9 6.9 13.1 10.6 13.2 11.0 1.2 89.2 8.1 4.7 38.1 13.2 14.8 12.9 44.4 37.2 9.3 4.4 20.7 13.5 9.5 8.6 16.2 21.0 17.9 10.5 8.1 17.1 5.4 23.4 11.3 7.5 24.7 9.0 9.1 4.1 5.7 8.6 51.4 3.7 8.9 3.2 6.6 9.8 6.6 16.9 17.1 165.4 96.7 26.1 14.1 5.2 34.2 12.9 25.5 5.2 KIF22 "Kid, KNSL4, OBP-1, OBP-2" ENSG00000079616 "Kinesin family member 22" Q14807 16 29790719-29805384 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Motor protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 88.5;lymphoid tissue: 73.0" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 288.7;Hepatocytes: 565.5;Proximal tubular cells: 194.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048213, HPA075670" Enhanced Supported "Nuclear speckles" NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 14: REH - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "Nuclear speckles" "HPA048213: AB_2680316, HPA075670: " "unprognostic (3.71e-2)" "prognostic favorable (3.87e-8)" "unprognostic (1.86e-1)" "unprognostic (2.21e-3)" "unprognostic (1.25e-1)" "unprognostic (6.06e-3)" "unprognostic (5.06e-3)" "unprognostic (2.70e-1)" "unprognostic (2.70e-1)" "unprognostic (4.73e-2)" "unprognostic (7.84e-2)" "unprognostic (2.10e-2)" "unprognostic (2.21e-2)" "unprognostic (3.67e-2)" "unprognostic (2.62e-1)" "unprognostic (3.94e-2)" "unprognostic (1.67e-1)" 9.2 7.0 9.5 19.7 9.9 88.5 13.4 8.1 10.4 10.5 6.9 22.6 16.6 8.2 8.6 22.3 12.3 6.4 10.8 9.5 8.9 11.2 8.3 8.5 34.1 8.4 8.3 8.2 7.3 33.8 9.2 15.7 8.3 24.9 20.6 8.9 10.5 12.0 8.4 32.8 16.9 8.0 8.9 18.6 11.8 28.3 9.4 73.0 26.0 11.0 34.7 10.1 13.3 9.3 89.3 103.9 120.6 87.6 8.0 11.9 104.8 65.8 52.1 123.1 113.9 97.9 103.3 130.6 60.4 34.4 61.2 90.0 118.9 67.5 57.4 84.8 100.4 72.4 115.1 119.0 2.7 79.1 76.0 6.7 17.7 68.5 51.3 17.1 67.2 144.7 109.4 104.1 65.5 186.5 173.1 196.1 101.8 65.7 59.6 237.9 110.6 122.4 44.9 45.0 99.8 65.4 48.5 94.7 33.1 39.4 84.8 105.2 29.8 63.8 66.6 57.7 72.6 96.6 105.3 141.4 41.9 129.0 83.3 58.7 14.1 39.5 49.7 21.1 37.3 30.4 50.0 53.1 14.7 27.3 40.0 38.4 6.2 31.5 18.3 9.6 56.5 40.5 9.5 9.9 8.1 10.4 9.5 8.9 8.4 8.3 8.3 8.9 9.4 9.3 13.9 32.1 115.4 5.5 23.0 30.8 25.8 56.7 52.9 27.5 56.5 56.4 288.7 57.2 38.5 69.9 25.0 81.7 20.1 44.2 62.6 16.6 9.9 29.5 18.9 29.2 41.4 85.2 4.8 50.1 85.4 50.1 25.0 31.1 43.6 29.5 49.2 565.5 46.3 6.7 6.1 39.5 34.6 47.7 40.4 8.5 15.5 36.7 35.6 4.7 38.6 69.8 29.9 4.0 5.3 17.3 44.0 12.8 49.9 26.1 18.0 194.0 29.7 20.5 13.1 23.7 34.2 50.9 61.6 41.4 27.6 76.9 34.2 12.2 42.3 22.5 KIF23 "KNSL5, MKLP-1, MKLP1" ENSG00000137807 "Kinesin family member 23" Q02241 15 69414246-69448427 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.6;lymphoid tissue: 15.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 24.2;Erythroid cells: 42.3;Extravillous trophoblasts: 32.4;Granulosa cells: 22.4;Spermatocytes: 70.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 4.6" "Group enriched" "Detected in many" 13 "granulocytes: 4.6;monocytes: 1.2;T-cells: 1.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB010414, HPA045208, HPA068831" Uncertain Enhanced "Nucleoplasm,Midbody ring,Mitotic spindle" Yes Yes "Cluster 49: Eosinophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Midbody ring, Mitotic spindle" "CAB010414: AB_631959, HPA045208: AB_2679254, HPA068831: AB_2686045" "unprognostic (1.29e-1)" "unprognostic (2.40e-1)" "unprognostic (5.57e-2)" "prognostic unfavorable (8.62e-4)" "unprognostic (1.86e-1)" "unprognostic (7.99e-3)" "prognostic unfavorable (3.18e-5)" "unprognostic (1.43e-3)" "unprognostic (4.25e-3)" "unprognostic (2.60e-1)" "prognostic unfavorable (3.69e-5)" "unprognostic (5.85e-3)" "unprognostic (0.00e+0)" "unprognostic (1.15e-2)" "unprognostic (2.59e-1)" "unprognostic (1.17e-1)" "unprognostic (9.17e-2)" 1.0 1.5 0.3 5.7 0.2 21.6 1.4 0.2 0.3 1.5 1.4 4.1 3.9 2.0 0.1 5.3 0.9 1.3 0.6 0.3 0.2 4.6 0.5 1.5 7.9 0.2 0.3 0.7 0.5 0.4 0.1 6.4 0.3 0.9 5.0 0.2 1.1 1.2 0.1 3.7 3.8 4.2 0.2 2.2 2.0 10.6 0.3 15.9 0.3 0.2 9.8 1.8 2.1 0.2 100.7 81.5 64.2 59.0 3.7 7.3 36.3 105.3 57.0 154.8 120.6 50.2 72.4 56.8 31.4 53.1 78.6 110.5 121.6 39.5 158.7 52.9 60.2 55.3 78.8 30.7 2.1 55.6 48.3 3.3 4.2 71.8 60.5 19.4 52.0 46.9 36.0 70.2 95.4 44.1 31.2 28.2 71.6 35.5 33.2 37.0 133.8 31.2 39.3 49.7 32.5 25.3 120.4 51.9 44.9 74.5 50.6 25.3 34.5 90.0 120.8 62.0 157.6 26.3 74.3 48.4 31.5 72.2 78.0 0.0 1.2 4.6 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.6 0.0 1.2 0.3 0.3 0.2 0.2 0.3 0.3 0.2 0.2 0.3 0.3 0.2 0.3 0.2 0.4 0.0 0.5 0.0 2.3 1.9 3.7 4.2 0.0 0.2 1.8 2.8 0.8 5.7 4.7 7.3 2.1 24.2 1.4 3.3 3.9 1.8 13.3 13.1 3.6 2.2 1.8 42.3 1.8 0.0 32.4 5.8 3.6 8.7 2.5 22.4 3.9 0.3 8.1 0.0 1.0 3.1 0.0 2.8 3.4 4.8 0.9 3.2 0.0 1.0 8.1 0.2 0.0 0.0 0.2 0.4 0.4 1.9 6.8 1.6 0.8 0.9 3.6 0.1 6.6 0.4 8.2 70.8 20.9 11.3 1.0 2.5 4.2 3.6 8.6 3.3 KIF2C "CT139, KNSL6, MCAK" ENSG00000142945 "Kinesin family member 2C" Q99661 1 44739818-44767767 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 33.0;lymphoid tissue: 37.4;testis: 76.5" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1860.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 2.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in some" "white matter: 2.1" "Not detected" "Not detected" "HPA006219, HPA079172" Enhanced Supported Nucleoplasm,Midbody,Centrosome Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Centrosome" Midbody "HPA006219: AB_2667540, HPA079172: " "unprognostic (3.29e-2)" "unprognostic (1.35e-2)" "unprognostic (1.03e-2)" "unprognostic (1.71e-3)" "unprognostic (2.77e-1)" "unprognostic (5.17e-2)" "prognostic unfavorable (3.07e-7)" "unprognostic (7.49e-3)" "unprognostic (3.33e-3)" "unprognostic (3.66e-1)" "prognostic unfavorable (6.86e-4)" "unprognostic (4.27e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.33e-3)" "unprognostic (1.49e-1)" "unprognostic (1.86e-2)" "unprognostic (2.41e-1)" 0.7 0.8 0.7 7.0 0.7 33.0 1.6 2.3 0.7 1.8 1.1 6.2 5.5 1.8 0.7 7.3 0.9 1.3 1.3 0.6 1.1 0.8 0.7 1.3 16.4 1.1 0.9 0.6 0.5 1.3 0.4 5.4 1.4 0.8 7.6 0.8 1.3 0.7 0.9 6.0 5.1 3.2 0.9 3.7 3.5 76.5 0.8 37.4 1.1 0.7 19.2 2.1 2.7 0.8 119.7 45.8 99.6 79.8 5.3 11.6 66.6 86.9 62.1 175.0 151.3 77.6 84.2 136.2 41.3 43.2 121.7 55.2 102.8 59.6 158.2 89.1 44.4 162.1 83.3 65.5 0.6 121.5 71.8 2.7 5.8 125.0 60.3 16.5 57.6 95.4 130.4 113.1 112.4 46.5 127.5 72.9 97.1 58.4 56.5 101.1 149.3 86.4 29.6 42.8 68.3 48.5 116.1 81.6 71.5 71.9 47.2 90.7 34.7 62.9 124.2 69.0 155.6 59.4 65.0 195.3 40.3 115.4 123.9 0.0 0.0 0.0 0.9 0.0 0.0 0.6 1.7 1.2 0.1 0.1 0.3 0.2 0.0 2.0 0.1 0.8 2.9 0.5 0.7 0.7 2.3 0.7 0.6 1.1 1.1 0.9 1.4 0.9 0.8 0.8 0.1 0.0 0.5 1.6 1.3 1.8 0.5 2.4 0.0 1.0 0.9 0.9 1.6 0.0 1.7 1.8 2.1 12.2 1.9 2.9 1.9 0.3 461.1 1.2 1.4 1.6 0.0 34.5 0.8 0.4 23.4 3.2 3.1 2.1 0.0 13.0 2.9 0.2 9.2 0.0 1.0 3.5 0.0 1.9 1.5 1860.6 9.3 3.4 0.0 1.0 4.3 0.4 0.0 0.5 0.2 0.1 0.2 6.8 7.8 0.8 0.3 0.2 0.3 0.2 6.6 0.8 3.4 60.6 36.8 4.6 0.4 3.7 2.7 0.8 7.4 0.7 KIF4A "FLJ12530, FLJ12655, FLJ14204, FLJ20631, HSA271784, KIF4, KIF4-G1, MRX100" ENSG00000090889 "Kinesin family member 4A" O95239 X 70290104-70420886 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA-binding, Motor protein" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.2;lymphoid tissue: 12.6" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 18.6;Erythroid cells: 29.5;Extravillous trophoblasts: 11.5;Granulosa cells: 12.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA034745, HPA034746, HPA061583" Approved Supported Nucleoplasm,Midbody Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Midbody" "HPA034745: AB_10670978, HPA034746: AB_10670173, HPA061583: AB_2684564" "unprognostic (8.17e-3)" "unprognostic (2.78e-2)" "unprognostic (1.02e-2)" "unprognostic (3.46e-3)" "unprognostic (3.20e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (7.37e-6)" "unprognostic (2.18e-3)" "unprognostic (5.06e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (9.44e-6)" "unprognostic (3.79e-2)" "unprognostic (0.00e+0)" "unprognostic (3.09e-2)" "unprognostic (1.10e-1)" "unprognostic (1.09e-1)" "unprognostic (1.47e-1)" 0.3 0.3 0.3 3.2 0.2 11.2 0.7 0.1 0.3 0.6 0.3 3.7 3.1 0.8 0.0 3.6 1.5 0.5 0.2 0.2 0.5 0.2 0.5 0.5 5.5 0.9 0.7 0.1 0.1 0.1 0.5 2.3 0.6 0.1 4.5 0.6 0.5 0.1 0.1 2.2 3.3 1.3 0.7 2.4 1.7 1.5 0.6 12.6 0.2 0.0 6.6 0.9 1.1 0.2 60.2 41.1 61.0 30.1 2.9 5.1 24.0 44.7 23.8 59.7 51.6 46.7 34.3 36.7 27.4 22.1 46.2 35.1 66.6 24.2 66.8 42.5 33.4 41.7 50.1 33.4 0.7 46.7 27.8 1.7 1.5 49.6 28.2 7.3 37.0 27.7 53.8 79.1 57.0 38.7 43.0 23.1 61.7 63.8 43.2 47.1 82.2 34.6 14.5 23.4 40.1 33.5 72.9 30.5 18.6 30.6 24.5 18.1 26.0 39.3 50.6 42.6 54.1 22.6 41.7 52.0 20.8 50.4 60.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.2 0.1 0.3 0.2 0.5 0.9 0.7 0.6 0.7 0.6 0.2 0.1 0.0 0.5 1.3 1.3 1.8 0.3 1.4 0.6 0.2 1.1 0.8 0.4 1.5 0.2 0.0 0.0 7.0 0.9 2.2 0.0 0.0 0.4 18.6 1.5 1.3 1.2 29.5 1.9 0.0 11.5 2.1 3.1 1.6 0.0 12.2 1.1 0.1 5.3 0.0 1.9 4.6 2.0 1.3 0.7 0.8 0.0 1.4 0.0 0.0 0.2 3.1 0.0 2.0 0.7 0.1 0.1 0.0 8.2 0.4 0.3 0.1 0.4 0.0 0.0 0.2 2.9 8.7 5.4 7.2 0.3 1.8 1.8 1.3 6.6 0.5 KIF5B "KNS, KNS1" ENSG00000170759 "Kinesin family member 5B" P33176 10 32009015-32056425 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Motor protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009846, HPA037589, HPA037590" Approved Enhanced "Centriolar satellite,Cytosol" NA Yes 97000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 10: Non-specific - Unknown function" "Centriolar satellite, Cytosol" "CAB009846: AB_2280915, HPA037589: AB_2675563, HPA037590: AB_2675564" "unprognostic (4.94e-3)" "unprognostic (1.70e-1)" "unprognostic (1.06e-1)" "unprognostic (1.84e-1)" "unprognostic (4.00e-2)" "unprognostic (6.21e-2)" "unprognostic (1.06e-2)" "unprognostic (1.84e-1)" "unprognostic (2.70e-1)" "unprognostic (6.37e-3)" "unprognostic (2.03e-1)" "unprognostic (2.60e-1)" "unprognostic (1.81e-1)" "unprognostic (2.43e-2)" "unprognostic (2.39e-1)" "unprognostic (8.06e-2)" "unprognostic (1.76e-1)" 59.7 41.8 110.0 46.7 128.2 84.9 45.3 107.7 149.7 47.3 75.6 66.4 52.0 54.1 30.3 52.7 39.2 59.8 87.4 85.8 100.2 44.7 31.9 52.5 39.9 121.9 123.8 27.6 41.8 91.6 22.9 54.4 120.6 65.9 63.6 45.1 39.1 52.0 65.0 38.9 54.7 81.3 128.1 48.1 51.4 64.4 116.8 44.0 50.5 67.3 36.6 60.8 29.8 143.4 115.8 96.4 127.3 89.9 89.2 97.7 54.4 155.6 73.3 117.6 99.6 106.6 124.0 78.7 65.8 185.8 66.9 93.3 117.6 99.4 156.4 68.4 64.1 100.2 87.9 104.5 102.5 70.5 105.6 79.9 138.0 135.8 94.0 93.4 152.8 68.2 122.9 80.5 164.7 69.7 74.0 39.7 20.7 110.1 43.4 95.7 237.2 32.6 90.6 79.5 123.3 89.9 120.4 47.5 117.3 88.0 57.5 99.4 128.4 118.7 111.0 139.3 117.2 24.2 29.8 90.9 113.2 142.2 114.1 41.8 25.9 44.0 19.1 33.0 18.7 23.7 24.0 20.6 24.7 24.3 21.1 20.8 51.1 24.3 35.7 47.9 29.4 18.4 110.0 128.2 107.7 149.7 85.8 100.2 121.9 123.8 120.6 128.1 116.8 143.4 160.3 182.7 206.8 49.3 86.3 213.1 177.7 200.6 66.0 181.9 119.0 103.8 396.0 115.8 198.4 104.8 100.1 121.0 125.5 145.0 45.0 209.4 185.5 167.8 171.4 181.0 132.3 69.2 44.6 176.0 134.9 141.2 85.6 158.9 91.2 159.7 88.5 46.2 132.7 151.4 56.0 227.3 213.6 111.8 129.1 51.8 59.0 137.2 101.4 84.3 169.3 160.5 82.4 61.9 83.3 202.2 164.9 130.9 84.2 254.1 120.2 59.5 206.1 123.8 85.5 176.0 244.8 566.0 195.6 87.6 236.7 331.9 116.0 137.4 208.1 246.8 KIFC1 "HSET, KNSL2" ENSG00000237649 "Kinesin family member C1" Q9BW19 6 33391823-33409896 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.7;lymphoid tissue: 47.5" "Cell type enhanced" "Detected in many" "Early spermatids: 32.0;Erythroid cells: 62.3;Extravillous trophoblasts: 39.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 1.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055997, HPA062674" Enhanced Approved Centrosome NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "HPA055997: AB_2683001, HPA062674: AB_2684829" "unprognostic (7.33e-2)" "unprognostic (1.28e-2)" "unprognostic (2.17e-1)" "unprognostic (2.65e-2)" "unprognostic (1.41e-1)" "unprognostic (2.30e-2)" "prognostic unfavorable (7.07e-8)" "unprognostic (6.34e-3)" "unprognostic (9.36e-3)" "unprognostic (8.58e-2)" "prognostic unfavorable (4.21e-4)" "unprognostic (1.83e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.17e-2)" "unprognostic (6.66e-2)" "unprognostic (1.48e-1)" "unprognostic (4.52e-1)" 1.1 1.1 0.2 10.6 0.3 39.7 2.2 0.3 1.2 2.5 0.4 8.0 8.8 1.8 0.2 11.7 0.8 1.5 0.6 0.7 0.3 0.8 1.0 2.3 24.6 0.4 0.7 2.0 0.7 0.3 0.6 5.5 0.5 0.9 8.2 0.4 2.1 0.2 0.2 9.8 8.1 4.1 0.2 5.3 4.7 12.3 0.6 47.5 0.7 0.4 24.9 2.7 3.9 0.5 133.5 47.9 120.6 124.2 5.2 8.1 64.0 82.5 48.4 122.6 104.6 80.6 53.3 120.2 38.3 41.5 102.0 88.1 87.1 60.7 79.7 114.3 60.3 93.9 71.6 73.5 0.5 96.0 75.7 2.5 4.7 73.2 38.8 13.8 64.2 87.5 76.0 112.3 81.0 86.2 125.7 103.2 47.5 67.6 48.4 129.7 110.7 61.4 38.4 42.8 100.1 57.2 54.3 91.9 44.1 51.3 78.7 105.4 32.2 74.6 104.6 56.2 128.9 58.2 132.4 126.1 18.8 94.8 101.0 0.4 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.6 0.2 0.2 0.0 0.0 0.0 1.0 0.3 0.0 1.6 0.5 0.2 0.3 0.3 1.2 0.7 0.3 0.4 0.7 0.5 0.2 0.6 0.5 0.4 0.0 2.5 1.0 4.1 5.6 1.5 4.6 2.2 0.4 2.8 2.2 0.5 0.0 1.9 0.0 0.0 18.7 3.7 8.8 0.0 0.7 32.0 2.7 1.9 2.4 0.0 62.3 0.3 0.0 39.6 4.2 4.1 6.1 1.3 15.0 1.8 0.3 14.3 0.0 0.3 8.0 2.0 2.4 9.8 12.0 0.3 4.7 3.6 1.0 3.1 0.3 0.0 1.0 0.6 0.3 2.1 0.7 12.0 0.9 2.1 0.7 0.8 0.5 0.0 2.5 7.5 13.9 9.6 14.4 3.7 6.7 5.7 0.6 12.1 3.1 KMT5A "PR-Set7, SET07, SET8, SETD8" ENSG00000183955 "Lysine methyltransferase 5A" Q9NQR1 12 123383773-123409353 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 62.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064495 Supported Nucleoplasm,Cytosol NA Yes "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "HPA064495: AB_2685273" "unprognostic (5.62e-2)" "unprognostic (4.45e-2)" "unprognostic (3.90e-1)" "unprognostic (3.04e-1)" "unprognostic (2.20e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (6.21e-7)" "unprognostic (3.88e-3)" "unprognostic (1.06e-2)" "unprognostic (1.64e-2)" "unprognostic (6.13e-2)" "unprognostic (3.44e-1)" "unprognostic (4.75e-3)" "unprognostic (4.27e-2)" "unprognostic (1.30e-1)" "unprognostic (4.39e-2)" "unprognostic (1.06e-1)" 13.7 10.1 22.6 15.3 22.1 39.2 13.1 20.8 23.2 22.2 18.7 17.7 12.8 21.3 12.9 40.7 21.7 13.6 17.0 22.2 20.6 13.7 14.0 15.5 15.4 22.4 22.7 12.0 19.7 11.4 10.7 16.5 22.9 30.2 14.4 11.7 24.0 19.7 24.4 28.1 15.6 16.7 21.4 16.8 16.9 7.9 23.3 17.9 25.7 15.3 16.6 16.6 25.7 23.9 37.3 24.3 27.8 43.5 18.1 30.9 40.1 57.4 26.3 32.0 26.9 28.8 21.9 84.9 33.1 37.5 11.7 35.8 41.6 21.7 33.3 39.3 45.0 68.8 26.4 15.2 26.5 54.8 18.8 15.1 27.1 34.7 32.8 30.2 26.2 36.4 136.8 38.1 27.5 29.9 58.1 84.9 13.8 34.6 29.0 70.4 22.1 24.1 22.8 43.4 37.9 30.9 51.3 28.3 28.6 23.6 39.6 75.3 32.4 35.2 26.0 42.3 42.3 23.0 25.9 75.9 24.6 29.6 29.9 2.3 1.2 4.3 1.3 2.1 2.7 1.7 1.6 2.1 1.0 1.1 0.9 1.1 1.8 2.3 2.1 2.0 1.5 0.3 22.6 22.1 20.8 23.2 22.2 20.6 22.4 22.7 22.9 21.4 23.3 23.9 34.5 12.8 14.5 0.0 12.7 0.0 17.6 0.0 20.5 20.8 32.0 27.3 0.0 7.2 6.8 27.6 6.2 15.1 22.4 10.4 7.9 9.2 10.1 46.8 43.8 20.7 4.9 62.1 0.0 9.4 16.6 14.7 15.8 41.1 2.5 21.3 30.4 19.5 17.7 3.3 0.0 22.2 0.0 16.8 0.0 3.2 16.1 19.6 0.0 0.0 3.4 28.7 7.2 0.0 0.0 13.6 9.6 42.9 15.9 24.1 14.3 13.1 11.7 17.9 6.6 23.2 19.7 9.7 10.2 38.8 0.0 14.2 14.5 18.4 12.7 22.5 KNL1 "AF15Q14, CASC5, CT29, D40, hKNL-1, hSpc105, KIAA1570, MCPH4, PPP1R55, Spc7" ENSG00000137812 "Kinetochore scaffold 1" Q8NG31 15 40594020-40664342 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 5.3;lymphoid tissue: 7.4;testis: 16.9" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 8.5;Extravillous trophoblasts: 11.3;Granulosa cells: 22.8;Hofbauer cells: 7.1;Proximal tubular cells: 11.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "HPA026624, HPA049647" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" Yes Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA026624: AB_10601696, HPA049647: AB_2680840" "unprognostic (5.35e-2)" "unprognostic (1.01e-1)" "unprognostic (5.59e-3)" "unprognostic (4.22e-2)" "unprognostic (1.59e-2)" "unprognostic (5.66e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (2.06e-2)" "unprognostic (1.43e-1)" "unprognostic (3.20e-4)" "unprognostic (2.22e-2)" "unprognostic (1.93e-12)" "unprognostic (3.07e-2)" "unprognostic (3.08e-1)" "unprognostic (8.45e-2)" "unprognostic (7.36e-2)" 0.2 0.1 0.1 1.9 0.0 5.3 0.3 0.2 0.2 0.2 0.2 1.3 1.6 0.3 0.2 1.0 0.1 0.3 0.1 0.1 0.1 0.5 0.7 0.4 3.6 0.1 0.3 0.0 0.0 0.3 0.0 1.3 0.1 0.1 1.4 0.2 0.2 0.0 0.0 0.8 1.7 0.7 0.0 0.6 0.9 16.9 0.3 7.4 0.3 0.1 3.4 0.5 0.2 0.1 19.1 9.3 18.0 13.8 0.5 2.6 8.6 20.5 8.1 16.0 13.1 11.6 7.2 11.9 6.1 9.3 12.0 21.9 17.6 9.7 16.3 21.4 5.0 35.5 15.5 3.9 0.0 26.2 17.8 0.5 0.4 10.8 6.4 2.1 13.8 20.9 22.9 19.2 18.3 6.1 23.5 6.1 9.4 11.3 9.5 21.2 25.8 5.9 2.6 15.6 15.9 7.7 17.7 10.6 2.1 5.9 11.1 9.0 13.1 18.7 16.3 21.9 11.7 7.5 27.9 22.3 7.6 18.5 18.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.3 0.5 0.0 0.1 0.1 0.1 0.1 0.0 0.6 0.0 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.3 0.1 0.0 0.3 0.1 0.3 0.0 0.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.1 1.1 0.0 0.0 1.8 1.8 0.0 8.5 2.6 0.0 1.9 0.2 0.0 3.5 3.5 1.9 0.0 0.0 0.0 0.6 11.3 4.2 0.0 2.9 0.0 22.8 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.1 0.0 0.0 11.5 0.7 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 3.7 1.9 1.7 0.0 0.0 KNSTRN "C15orf23, FLJ14502, kinastrin, SKAP, TRAF4AF1" ENSG00000128944 "Kinetochore localized astrin (SPAG5) binding protein" Q9Y448 15 40382721-40394246 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 63.6;thyroid gland: 53.1" "Cell type enhanced" "Detected in many" "Early spermatids: 328.2;Late spermatids: 600.1;Spermatocytes: 145.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" HPA042027 Enhanced Enhanced "Plasma membrane,Mitotic spindle,Centriolar satellite" Yes Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" "Mitotic spindle, Centriolar satellite" "Plasma membrane" "HPA042027: AB_10797378" "unprognostic (2.35e-3)" "unprognostic (6.83e-2)" "unprognostic (3.01e-1)" "unprognostic (5.23e-3)" "unprognostic (6.19e-2)" "unprognostic (2.28e-2)" "unprognostic (1.54e-3)" "unprognostic (2.47e-3)" "unprognostic (1.23e-1)" "unprognostic (2.55e-1)" "prognostic unfavorable (3.43e-5)" "unprognostic (6.31e-2)" "prognostic unfavorable (7.88e-9)" "unprognostic (1.70e-1)" "unprognostic (1.58e-1)" "unprognostic (2.67e-1)" "unprognostic (1.52e-2)" 8.0 6.2 6.3 8.1 7.1 14.1 14.3 7.7 8.6 5.1 4.5 7.9 9.2 6.4 12.3 9.1 5.7 4.4 7.4 7.2 6.2 7.2 12.0 5.8 14.5 6.2 6.2 5.1 5.0 8.4 5.6 10.7 6.5 6.8 10.4 9.0 10.3 7.2 12.2 6.7 6.2 10.2 5.9 7.1 10.2 63.6 6.1 25.6 53.1 12.4 16.1 5.6 5.6 7.7 103.4 47.5 92.7 61.0 20.1 30.9 48.1 69.9 54.0 141.0 123.3 102.6 44.2 39.7 34.8 47.3 112.1 115.7 100.0 64.8 126.5 70.8 48.8 117.7 107.4 65.2 18.9 63.8 58.6 16.1 36.5 71.3 70.6 34.5 80.3 97.6 86.3 66.8 120.0 52.2 55.6 51.2 58.6 87.7 71.2 56.4 69.7 45.7 49.7 42.3 89.9 62.5 58.3 63.3 15.1 55.8 66.5 45.3 41.6 67.5 68.8 69.7 98.3 56.5 98.6 70.5 41.8 84.0 56.5 13.2 17.6 17.4 7.9 24.3 6.8 9.5 5.7 7.0 18.4 11.2 5.4 5.5 9.7 9.8 47.8 12.7 9.4 7.1 6.3 7.1 7.7 8.6 7.2 6.2 6.2 6.2 6.5 5.9 6.1 7.7 2.4 9.6 1.1 2.6 4.1 2.2 2.9 7.6 3.4 8.2 4.2 3.4 7.3 1.5 5.4 0.0 8.4 25.2 2.5 1.9 3.9 8.5 328.2 5.9 4.9 3.7 2.4 34.3 5.1 9.3 40.8 5.2 5.6 4.4 1.3 16.9 3.6 8.0 21.6 5.0 4.9 5.3 14.2 9.8 2.0 600.1 9.0 8.2 3.6 4.7 8.0 8.5 6.2 2.0 4.3 12.3 0.5 7.2 12.6 4.9 2.8 5.8 7.2 8.5 0.0 3.7 6.5 145.7 19.2 7.0 1.4 21.1 5.1 8.5 6.4 3.0 KNTC1 "KIAA0166, ROD" ENSG00000184445 "Kinetochore associated 1" P50748 12 122527246-122626396 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 42.3" "Cell type enhanced" "Detected in many" "Early spermatids: 30.4;Erythroid cells: 29.5;Plasma cells: 28.7;Spermatocytes: 40.7;Spermatogonia: 39.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA025241 Approved Supported "Plasma membrane,Cytosol" NA Yes "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Plasma membrane" "HPA025241: AB_1852629" "unprognostic (1.17e-1)" "unprognostic (2.12e-3)" "unprognostic (2.51e-1)" "unprognostic (1.53e-2)" "unprognostic (9.34e-2)" "prognostic favorable (8.69e-4)" "prognostic unfavorable (4.79e-6)" "unprognostic (4.04e-2)" "unprognostic (7.20e-3)" "unprognostic (1.59e-2)" "unprognostic (4.78e-2)" "unprognostic (1.92e-2)" "prognostic unfavorable (7.89e-8)" "unprognostic (2.17e-2)" "unprognostic (3.08e-1)" "unprognostic (8.04e-2)" "unprognostic (1.74e-1)" 7.1 7.6 3.7 11.7 3.6 42.3 7.6 4.9 5.3 9.1 3.5 9.8 9.0 5.3 5.2 12.2 6.8 3.4 4.1 3.6 3.4 6.7 6.4 8.0 16.4 3.8 3.4 8.2 6.6 2.9 5.7 5.8 3.9 7.3 11.9 5.5 7.7 2.9 2.5 15.1 14.5 4.6 3.1 18.2 7.2 28.2 4.0 17.8 5.4 1.4 17.4 6.2 8.9 5.0 33.8 27.6 77.8 17.9 5.9 10.8 35.0 30.6 19.8 29.7 27.9 26.2 27.6 40.2 15.6 14.9 19.5 45.4 34.1 19.1 39.1 28.8 23.7 49.7 57.1 27.1 2.0 49.3 32.8 5.8 4.3 30.7 20.2 15.5 20.5 50.5 50.4 29.4 22.6 25.0 40.9 113.0 39.4 16.3 34.5 55.4 37.8 44.8 17.8 35.6 24.1 31.0 55.7 11.7 16.7 46.2 44.4 28.1 15.1 33.7 32.3 33.3 36.3 39.3 42.3 61.0 20.1 31.3 39.6 2.5 0.5 1.8 0.7 0.7 0.6 1.6 1.1 1.3 0.5 0.9 0.8 1.0 1.6 0.9 1.0 0.8 0.5 0.3 3.7 3.6 4.9 5.3 3.6 3.4 3.8 3.4 3.9 3.1 4.0 5.0 4.3 0.0 2.6 3.3 8.1 4.2 1.9 1.9 2.2 2.2 3.1 3.4 1.8 0.0 1.9 5.5 4.2 7.0 3.8 3.0 0.0 1.5 30.4 3.3 3.9 2.9 0.0 29.5 6.2 0.4 5.9 2.9 10.2 5.2 1.3 14.7 2.2 1.3 4.8 0.0 4.5 2.3 0.0 2.2 4.7 17.7 4.7 4.0 1.8 4.7 1.6 1.1 2.1 2.5 4.4 0.8 1.0 3.0 28.7 1.0 1.5 0.5 5.0 5.0 6.6 3.1 2.9 40.7 39.9 4.9 2.3 2.9 5.3 2.1 5.8 1.6 KPNA2 "IPOA1, QIP2, RCH1, SRP1alpha" ENSG00000182481 "Karyopherin subunit alpha 2" P52292 17 68035636-68047364 "Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 209.1" "Cell type enhanced" "Detected in all" "Early spermatids: 863.9;Extravillous trophoblasts: 279.7;Spermatocytes: 552.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015460, HPA041270" Enhanced Enhanced Nucleoplasm,Cytosol Yes Yes 160000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "CAB015460: AB_831493, HPA041270: AB_2677385" "unprognostic (2.78e-2)" "unprognostic (1.54e-1)" "prognostic favorable (3.83e-4)" "unprognostic (2.14e-2)" "unprognostic (1.64e-1)" "unprognostic (5.16e-3)" "prognostic unfavorable (2.12e-10)" "prognostic unfavorable (5.77e-4)" "unprognostic (3.34e-2)" "unprognostic (7.59e-2)" "unprognostic (3.72e-3)" "unprognostic (3.08e-2)" "prognostic unfavorable (1.26e-13)" "unprognostic (3.07e-2)" "unprognostic (1.78e-1)" "unprognostic (9.50e-2)" "prognostic unfavorable (2.19e-4)" 25.9 15.9 18.9 45.2 19.3 99.2 15.2 18.7 23.3 17.4 15.7 30.7 26.1 17.6 25.7 41.4 10.8 19.4 23.9 20.8 24.7 16.2 23.1 17.9 72.1 19.1 20.5 6.5 10.0 10.6 15.6 43.8 22.2 8.2 35.8 22.2 15.4 11.6 14.8 21.0 23.3 34.6 20.5 28.3 19.0 209.1 20.0 94.7 10.9 16.7 104.9 38.6 17.7 22.7 556.0 712.3 667.1 264.4 95.7 93.9 421.1 467.9 372.9 758.1 587.9 499.5 250.4 514.4 146.7 273.4 375.1 297.4 753.8 359.4 870.7 203.8 437.5 446.5 311.7 482.7 101.9 387.6 294.3 58.1 69.3 426.0 267.2 105.8 746.8 211.0 360.8 346.0 686.1 517.3 484.4 249.8 451.4 455.2 365.8 271.5 605.1 280.6 304.0 250.0 262.2 286.3 269.5 839.1 291.9 609.6 495.6 196.9 288.6 416.7 506.2 290.6 647.3 291.5 451.9 504.7 203.0 334.9 458.0 30.1 31.0 12.7 24.1 46.5 19.2 45.8 18.8 27.3 56.2 39.6 13.3 21.5 0.9 43.9 39.6 41.4 37.7 31.3 18.9 19.3 18.7 23.3 20.8 24.7 19.1 20.5 22.2 20.5 20.0 22.7 41.0 12.8 31.0 6.2 49.4 109.7 32.2 73.7 43.3 20.1 39.8 45.5 13.8 7.2 39.7 18.4 8.4 128.3 96.4 27.7 15.6 31.4 863.9 70.8 55.1 48.6 42.9 70.9 8.5 25.5 279.7 64.9 31.1 68.0 44.4 68.2 21.8 17.2 126.0 32.0 7.3 27.6 97.6 42.9 132.1 266.6 19.3 60.0 53.4 3.7 72.1 31.2 18.6 6.6 5.9 20.7 11.9 14.7 60.3 27.6 9.3 31.2 22.7 20.0 32.9 52.4 74.1 552.9 185.2 61.3 88.5 118.9 79.8 28.0 49.3 24.2 LBR "DHCR14B, TDRD18" ENSG00000143815 "Lamin B receptor" Q14739 1 225401502-225428925 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "DNA-binding, Oxidoreductase, Receptor" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 248.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062236 Enhanced Supported "Nuclear membrane" NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" "Nuclear membrane" "HPA062236: AB_2684721" "unprognostic (2.57e-1)" "unprognostic (1.57e-1)" "unprognostic (2.14e-3)" "unprognostic (1.32e-2)" "unprognostic (7.96e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (7.30e-4)" "unprognostic (3.60e-2)" "unprognostic (1.11e-2)" "unprognostic (3.43e-2)" "unprognostic (1.05e-1)" "unprognostic (1.99e-1)" "unprognostic (6.42e-2)" "unprognostic (2.08e-1)" "unprognostic (5.45e-1)" "unprognostic (8.32e-2)" "unprognostic (2.78e-1)" 28.6 9.1 8.8 53.2 9.7 95.7 17.1 9.3 11.9 27.3 9.2 61.4 40.7 47.0 44.4 29.7 31.8 21.7 10.0 8.5 10.1 19.4 47.3 19.2 81.6 12.0 9.8 19.4 16.9 5.6 6.5 27.6 11.2 23.8 46.2 5.3 11.1 36.7 9.8 13.8 39.9 41.4 10.2 41.5 28.2 20.5 9.5 105.5 11.8 12.8 70.7 32.3 23.0 13.1 122.2 42.0 154.9 69.3 64.8 39.7 77.3 31.2 39.2 65.0 69.0 87.2 207.2 248.4 66.6 32.8 38.6 88.8 114.2 32.9 98.5 142.2 107.1 61.4 40.4 81.5 39.9 274.7 105.5 34.3 21.3 58.9 52.0 33.1 82.9 117.4 189.6 164.6 44.4 16.3 254.9 156.6 140.6 121.8 14.2 164.9 141.4 234.0 75.6 52.7 40.6 53.4 52.7 39.6 26.6 68.2 53.3 181.0 50.5 17.6 91.7 49.3 115.9 56.6 83.0 274.5 24.3 120.5 61.2 83.6 44.3 67.3 43.6 31.6 50.9 39.0 43.5 48.8 38.4 39.5 42.4 52.9 211.4 41.3 25.2 21.5 61.9 69.8 8.8 9.7 9.3 11.9 8.5 10.1 12.0 9.8 11.2 10.2 9.5 13.1 98.1 28.9 36.4 13.4 86.4 27.0 33.4 17.3 21.6 4.5 11.9 11.0 8.5 48.6 34.4 31.3 6.2 40.5 98.3 33.4 5.9 23.6 1.2 31.5 31.0 53.1 27.0 248.9 10.5 19.8 23.9 29.0 29.0 53.9 10.1 24.0 48.5 73.6 44.4 11.8 14.3 43.0 12.2 88.5 18.1 3.4 33.8 71.7 26.6 19.7 56.0 11.6 82.4 37.2 34.1 20.6 24.6 32.4 74.0 32.9 19.3 26.0 26.0 10.4 39.5 13.9 46.6 21.0 26.7 68.4 35.5 11.1 81.3 13.2 73.8 36.7 LGALS1 GBP ENSG00000100097 "Galectin 1" P09382 22 37675636-37679802 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3949.7;Langerhans cells: 4906.5;monocytes: 7118.4;Smooth muscle cells: 4703.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 1649.6" "HPA000646, HPA000687, HPA001130, CAB002157" Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" No Yes 10000000 20000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" Cytosol Nucleoplasm "CAB002157: AB_563734, HPA000646: AB_1078935, HPA000687: AB_2756309, HPA001130: AB_2756311" "unprognostic (1.65e-1)" "unprognostic (8.13e-2)" "unprognostic (5.13e-2)" "prognostic favorable (2.36e-5)" "unprognostic (6.38e-2)" "unprognostic (2.67e-3)" "prognostic unfavorable (3.06e-4)" "unprognostic (3.22e-3)" "unprognostic (4.91e-3)" "unprognostic (2.51e-1)" "unprognostic (6.16e-3)" "unprognostic (8.06e-2)" "prognostic unfavorable (1.18e-10)" "unprognostic (2.24e-2)" "unprognostic (8.13e-2)" "unprognostic (9.47e-2)" "prognostic unfavorable (5.10e-4)" 1921.2 778.5 482.4 523.8 520.7 324.7 1490.9 613.5 695.3 1805.7 465.2 1634.7 197.7 2270.1 196.8 387.4 1147.0 556.0 1397.4 457.7 549.0 362.4 277.4 920.2 176.7 694.5 576.1 1440.2 155.5 188.1 254.8 426.1 661.5 903.0 207.2 39.5 397.5 756.3 1172.9 472.8 475.3 1353.4 593.8 460.7 582.7 244.9 624.9 153.9 290.9 691.9 116.9 1059.7 1156.4 782.4 2850.9 1664.3 36.5 1440.9 3314.6 6505.1 32.7 6450.7 7619.4 4761.9 4716.9 189.6 368.3 3.3 649.1 6661.4 1609.2 296.3 58.8 4309.2 1663.3 2917.2 30.9 251.3 1606.3 791.1 2155.3 145.1 3167.7 4031.7 294.2 3785.7 1609.9 4271.1 5325.7 1.7 186.6 1163.4 3771.1 1287.6 5.2 2038.4 14.3 629.6 3914.9 5.4 2388.6 799.7 2000.0 6.4 5.5 843.4 1287.4 224.3 1644.5 66.7 1187.2 1689.0 7122.0 6224.0 3070.2 2788.9 3349.3 701.8 530.6 13.6 7291.9 762.0 2535.9 1086.5 3047.4 110.2 766.5 2320.4 113.6 567.7 694.9 754.2 3653.1 287.5 114.3 478.1 122.2 415.4 2556.7 899.2 1514.7 4667.0 482.4 520.7 613.5 695.3 457.7 549.0 694.5 576.1 661.5 593.8 624.9 782.4 1505.8 166.7 90.4 12.7 294.3 730.3 144.0 2796.6 49.5 10.0 144.2 477.9 986.3 74.4 213.4 163.7 6.2 88.0 466.5 49.9 17.6 690.2 30.9 183.0 3011.6 1063.6 3.0 74.9 7.5 90.4 1573.3 2540.4 28.1 230.3 540.0 172.2 653.2 614.1 3949.7 8.4 5.4 8.4 339.7 2159.0 4906.5 106.4 975.5 1700.0 2856.6 15.9 7118.4 278.0 588.1 4.0 17.1 233.5 6.1 1300.7 590.9 118.8 0.5 28.7 109.8 45.4 1650.1 1873.6 4703.8 33.8 13.1 18.2 588.0 151.5 767.5 197.2 11.6 57.0 LIMK2 ENSG00000182541 "LIM domain kinase 2" P53671 22 31212239-31280080 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 115.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 40.0;neutrophil: 96.9" "Lineage enriched" "Detected in all" 6 "granulocytes: 96.9" "Cell line enhanced" "Detected in all" "BEWO: 135.5;hTCEpi: 251.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008183, CAB019313, HPA053882" Approved Supported Nucleoplasm,Cytosol NA Yes "Cluster 5: Granulocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "CAB019313: , HPA008183: AB_1079252, HPA053882: AB_2682291" "unprognostic (1.79e-1)" "unprognostic (1.95e-1)" "unprognostic (1.04e-2)" "unprognostic (2.59e-2)" "unprognostic (1.39e-1)" "unprognostic (2.42e-2)" "unprognostic (4.02e-2)" "unprognostic (5.99e-2)" "unprognostic (1.21e-1)" "unprognostic (2.95e-1)" "unprognostic (3.96e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (4.57e-6)" "unprognostic (4.48e-2)" "unprognostic (1.48e-2)" "unprognostic (5.72e-2)" "unprognostic (1.37e-1)" 20.1 14.4 25.5 39.8 27.3 53.8 30.9 25.8 22.1 26.4 32.6 34.0 21.2 17.0 7.7 71.8 34.2 21.3 14.3 20.8 27.7 27.7 33.0 46.8 23.2 37.8 34.2 21.6 28.8 27.0 21.9 48.0 32.8 36.7 34.7 25.5 50.7 19.1 18.8 71.5 29.3 15.9 32.7 37.5 30.0 19.2 33.6 21.3 42.0 9.2 17.8 25.7 45.3 33.1 26.6 4.4 17.9 10.0 7.6 8.8 135.5 17.2 8.0 16.9 14.2 22.7 12.2 25.8 29.9 26.0 8.1 52.6 20.9 90.3 10.6 19.1 22.8 18.8 21.1 24.7 11.4 35.1 33.1 14.3 251.5 13.7 41.0 114.5 43.6 20.6 10.7 18.2 23.3 20.9 21.5 12.0 16.7 68.3 6.7 28.1 30.0 14.3 19.6 62.3 22.8 20.4 13.0 82.1 35.1 54.8 68.7 13.9 26.6 15.1 23.5 8.3 16.3 10.0 16.2 22.4 9.6 16.4 6.6 5.8 5.1 40.0 3.1 3.5 5.9 2.0 5.7 4.3 1.9 2.4 5.6 4.4 96.9 6.7 1.4 4.4 15.2 4.4 25.5 27.3 25.8 22.1 20.8 27.7 37.8 34.2 32.8 32.7 33.6 33.1 19.5 32.1 17.9 16.3 5.2 35.9 37.7 24.8 59.2 9.4 18.0 23.2 25.1 10.0 32.6 5.5 20.9 69.8 15.3 39.3 3.9 13.0 1.4 49.6 19.2 22.4 13.2 10.3 6.4 45.0 52.4 7.6 48.9 41.6 23.5 8.6 14.3 7.1 18.2 3.3 11.3 42.8 18.3 8.9 8.2 1.6 4.4 13.8 3.6 16.9 5.4 16.6 2.1 2.5 15.5 25.9 21.2 4.5 6.2 27.1 12.0 10.5 36.3 22.8 19.7 7.5 17.2 15.6 18.4 46.1 39.1 115.5 9.3 7.1 51.7 29.9 LTBR "D12S370, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFRSF3" ENSG00000111321 "Lymphotoxin beta receptor" P36941 12 6375045-6391571 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Host-virus interaction" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 71.3;intermediate monocyte: 66.3;myeloid DC: 49.8;neutrophil: 45.0;non-classical monocyte: 50.1" "Group enriched" "Detected in many" 36 "dendritic cells: 49.8;granulocytes: 45.0;monocytes: 71.3" "Cell line enhanced" "Detected in many" "HHSteC: 393.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026202, HPA061617" Uncertain Supported "Golgi apparatus" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Golgi apparatus" "CAB026202: , HPA061617: AB_2732666" "unprognostic (2.60e-2)" "unprognostic (1.24e-2)" "unprognostic (7.75e-3)" "unprognostic (2.23e-2)" "unprognostic (3.01e-2)" "unprognostic (3.24e-3)" "prognostic unfavorable (5.13e-4)" "unprognostic (2.08e-2)" "unprognostic (2.24e-2)" "unprognostic (1.43e-1)" "unprognostic (2.45e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (5.92e-4)" "unprognostic (3.66e-2)" "unprognostic (9.84e-3)" "unprognostic (6.91e-2)" "unprognostic (2.86e-1)" 67.6 64.4 13.9 36.4 14.6 11.7 60.3 14.7 15.9 65.8 18.0 72.7 48.6 68.1 20.7 81.3 49.6 48.3 37.2 13.3 15.8 55.1 135.8 66.0 14.6 19.6 17.3 46.3 78.7 54.9 26.3 48.6 18.8 61.9 34.3 1.9 61.5 44.0 26.3 75.1 51.1 62.6 17.4 44.8 67.7 13.3 18.1 11.7 57.2 23.5 18.0 65.8 65.1 17.0 98.2 130.3 0.0 41.1 245.9 183.7 89.9 67.9 153.1 98.8 101.1 62.0 148.7 0.1 39.5 145.7 0.5 112.2 0.5 140.5 38.9 0.0 0.2 58.1 53.2 36.6 393.1 4.1 94.6 270.8 255.2 70.7 197.1 102.6 91.2 0.0 55.5 0.5 115.0 93.5 0.4 29.3 1.2 155.7 74.4 0.0 6.6 0.2 149.2 112.2 0.7 0.5 63.6 122.9 143.6 5.0 20.5 105.3 58.0 34.6 39.6 129.0 72.1 0.0 0.4 0.1 14.6 35.9 129.5 5.4 71.3 0.5 0.2 66.3 0.0 0.1 0.1 0.1 49.8 0.1 0.3 0.2 45.0 1.5 50.1 11.8 0.1 27.2 13.9 14.6 14.7 15.9 13.3 15.8 19.6 17.3 18.8 17.4 18.1 17.0 47.0 60.9 68.9 2.9 3.6 39.0 87.2 46.4 72.3 4.1 33.9 35.9 15.5 45.8 60.7 31.3 0.0 31.3 12.4 78.3 9.8 52.2 0.7 23.8 48.6 49.3 52.0 15.8 0.5 99.8 43.6 50.5 89.7 45.2 29.7 30.1 50.7 66.5 48.7 0.0 0.5 57.1 34.6 77.3 34.6 5.1 52.8 50.8 23.2 14.0 43.1 9.6 11.3 5.5 1.1 69.5 82.3 39.9 3.3 110.7 136.9 30.1 42.8 1.6 26.3 33.1 42.0 1.6 0.9 78.9 61.7 37.5 4.9 28.0 63.4 97.6 LZTS2 "KIAA1813, LAPSER1" ENSG00000107816 "Leucine zipper tumor suppressor 2" Q9BRK4 10 100996618-101007836 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 70.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044956 Approved Approved "Plasma membrane,Cytosol" No Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "HPA044956: AB_10795989" "unprognostic (1.42e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (8.23e-4)" "unprognostic (8.18e-2)" "unprognostic (4.64e-2)" "unprognostic (1.56e-1)" "unprognostic (5.49e-3)" "unprognostic (3.56e-1)" "unprognostic (7.57e-2)" "unprognostic (4.58e-2)" "unprognostic (2.72e-1)" "unprognostic (1.38e-1)" "prognostic unfavorable (3.39e-4)" "unprognostic (7.63e-2)" "unprognostic (1.86e-1)" "unprognostic (5.46e-3)" "unprognostic (1.76e-3)" 69.9 66.0 46.8 14.9 65.5 14.4 63.3 58.0 54.1 74.3 25.8 96.3 17.5 90.3 17.7 41.0 69.2 19.8 58.9 41.2 45.8 51.8 18.0 57.1 12.1 63.7 64.3 78.6 29.5 29.1 43.6 28.5 58.5 69.5 8.9 5.9 44.3 40.6 37.8 48.9 43.0 26.6 49.0 44.4 54.9 36.2 64.1 10.8 57.6 18.0 8.1 84.1 54.4 78.9 32.9 43.1 34.6 59.7 45.0 36.3 70.8 38.7 72.8 31.9 36.0 50.5 26.6 13.1 35.1 52.5 23.0 54.6 21.5 28.2 7.8 12.8 31.9 12.1 46.4 66.3 63.6 6.4 15.2 66.1 20.2 25.1 30.1 67.3 32.8 15.6 38.7 7.3 28.7 31.6 5.8 15.8 38.8 12.6 35.2 74.7 101.3 13.5 24.4 39.3 8.4 62.8 26.3 11.9 99.9 18.6 61.0 51.6 42.1 37.9 42.6 40.5 20.7 14.0 10.2 3.3 64.0 17.7 19.4 0.0 0.7 0.4 2.7 0.4 3.7 2.3 3.4 3.0 1.1 2.9 3.5 3.0 0.3 2.9 0.1 1.8 3.0 1.5 46.8 65.5 58.0 54.1 41.2 45.8 63.7 64.3 58.5 49.0 64.1 78.9 34.7 16.0 10.5 20.2 5.3 13.4 9.0 12.4 19.4 14.4 21.7 20.3 5.2 11.5 9.4 5.5 6.2 18.6 1.9 8.0 7.9 19.1 6.8 7.9 20.5 22.9 16.7 5.0 6.8 12.6 13.2 21.8 14.8 13.0 1.3 38.9 18.5 2.6 22.2 18.5 7.7 17.8 16.2 7.2 9.2 4.1 25.7 8.4 16.0 13.1 4.8 18.9 4.1 9.0 70.3 13.3 7.9 29.3 5.4 18.1 6.5 8.3 6.1 4.0 26.3 21.1 40.7 3.8 15.0 10.8 12.1 47.1 6.0 26.9 15.1 9.7 MAD2L1 "HSMAD2, MAD2" ENSG00000164109 "Mitotic arrest deficient 2 like 1" Q13257 4 120055623-120066858 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.9;lymphoid tissue: 5.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 81.8;Extravillous trophoblasts: 119.2;Spermatocytes: 127.8;Spermatogonia: 76.2" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003348 Uncertain Approved Nucleoplasm NA Yes "Cluster 20: T-cells - T-cell receptor" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA003348: AB_10603014" "unprognostic (4.08e-3)" "unprognostic (7.31e-2)" "unprognostic (5.17e-3)" "unprognostic (1.10e-2)" "unprognostic (1.27e-1)" "unprognostic (5.54e-2)" "prognostic unfavorable (5.15e-5)" "prognostic unfavorable (2.17e-4)" "unprognostic (6.74e-3)" "unprognostic (1.47e-1)" "unprognostic (3.20e-3)" "unprognostic (3.87e-3)" "prognostic unfavorable (3.07e-11)" "unprognostic (3.06e-2)" "unprognostic (4.05e-1)" "unprognostic (1.03e-1)" "unprognostic (9.70e-2)" 0.3 0.4 0.5 2.1 0.6 5.9 1.2 0.8 0.7 0.5 0.2 2.2 1.8 0.7 0.3 1.6 1.4 0.4 0.5 0.5 0.5 0.4 0.5 0.4 4.0 0.4 0.4 0.5 0.2 0.4 0.1 1.4 0.5 0.6 2.6 1.0 0.3 0.5 0.2 1.0 1.9 0.8 0.4 0.8 0.9 2.3 0.4 5.7 0.4 0.2 3.6 0.7 0.5 0.6 27.2 11.6 26.9 17.5 2.8 3.4 11.5 21.0 11.8 21.5 16.5 15.7 16.3 39.6 6.8 7.6 9.5 7.1 27.1 16.1 30.0 18.8 18.8 22.0 10.5 14.9 0.8 36.3 12.0 1.9 2.3 14.6 9.1 5.4 12.6 16.4 26.7 22.0 11.4 12.0 35.0 15.6 18.3 14.1 13.0 17.8 35.9 16.2 8.7 10.3 28.4 20.1 10.5 12.8 6.5 12.9 8.4 13.0 7.8 14.2 16.1 14.6 27.0 20.1 23.2 25.7 13.3 18.4 19.1 0.9 0.1 0.1 0.4 0.1 0.6 0.5 1.2 1.0 0.1 0.4 1.1 1.1 0.3 0.9 0.2 0.7 1.3 0.5 0.5 0.6 0.8 0.7 0.5 0.5 0.4 0.4 0.5 0.4 0.4 0.6 2.4 0.0 1.3 1.0 11.5 17.3 7.3 23.5 4.0 9.7 7.2 8.3 3.4 1.5 6.0 7.3 2.1 52.0 7.6 7.5 0.0 3.4 2.4 31.3 6.0 5.4 1.8 81.8 1.3 1.5 119.2 13.7 8.6 7.8 15.2 34.6 3.9 2.9 27.9 20.2 1.2 13.7 36.7 7.3 13.4 4.8 4.7 6.1 8.8 0.0 3.1 12.3 5.2 0.5 1.0 1.6 3.7 1.5 33.1 5.0 3.7 7.2 12.9 3.8 13.1 7.3 14.9 127.8 76.2 26.0 8.9 10.8 20.1 11.9 29.2 8.7 MAGEB2 "CT3.2, DAM6, MAGE-XP-2, MGC26438" ENSG00000099399 "MAGE family member B2" O15479 X 30215563-30220089 "Predicted intracellular proteins" "Ubl conjugation pathway" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 60 "testis: 29.1" "Group enriched" "Detected in some" 4 "Spermatocytes: 24.7;Spermatogonia: 95.8" "Cancer enriched" "Detected in many" 7 "testis cancer: 33.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HL-60: 92.4;K-562: 66.9;Karpas-707: 77.0;U-2 OS: 89.9;U-266/70: 149.7;U-266/84: 168.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA065224, HPA074544, HPA075519" Enhanced Approved Cytosol NA Yes "Cluster 36: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Cytosol "HPA065224: AB_2685437, HPA074544: AB_2732258, HPA075519: AB_2732294" "unprognostic (4.52e-1)" "unprognostic (2.55e-2)" "unprognostic (6.39e-2)" "unprognostic (5.02e-1)" "unprognostic (6.57e-2)" "unprognostic (1.79e-2)" "unprognostic (1.00e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 6.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 92.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 66.9 77.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.2 0.0 0.5 0.0 14.8 0.2 0.0 89.9 0.3 0.3 149.7 168.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 3.1 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 24.7 95.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 MAMDC4 "AEGP, DKFZp434M1411, EDTB" ENSG00000177943 "MAM domain containing 4" Q6UXC1 9 136850943-136860799 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 30.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 22.9;Hepatocytes: 26.6;Horizontal cells: 16.8;Intestinal goblet cells: 21.8;Proximal enterocytes: 23.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 16.9" "Region enhanced" "Detected in single" "cerebellum: 1.2" "Low region specificity" "Detected in all" "CAB026377, HPA059977" Approved Nucleoplasm,Cytosol NA Yes "Cluster 18: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "CAB026377: , HPA059977: AB_2684186" "unprognostic (2.79e-1)" "unprognostic (7.90e-2)" "unprognostic (4.09e-3)" "unprognostic (6.86e-2)" "unprognostic (8.33e-2)" "unprognostic (2.66e-4)" "unprognostic (3.20e-2)" "unprognostic (2.39e-1)" "unprognostic (1.31e-1)" "unprognostic (7.37e-2)" "prognostic favorable (1.88e-6)" "unprognostic (8.22e-3)" "unprognostic (1.58e-2)" "unprognostic (1.22e-3)" "unprognostic (9.22e-2)" "unprognostic (2.18e-1)" "unprognostic (1.08e-2)" 2.7 3.2 1.6 1.6 2.0 1.4 2.4 7.2 3.1 3.9 1.5 7.3 3.9 2.5 0.3 2.8 4.5 0.7 6.1 1.4 1.3 8.3 30.7 3.6 0.9 2.1 1.9 3.1 7.4 0.6 15.0 1.0 2.2 7.7 0.8 0.7 3.3 1.0 2.5 2.0 5.8 0.5 1.1 9.7 3.9 4.3 1.7 0.6 11.4 0.9 0.2 2.6 3.1 3.3 1.5 2.5 1.3 2.6 0.5 0.1 16.9 2.5 0.3 0.3 0.5 1.9 1.4 1.3 0.6 0.6 0.7 2.1 0.3 1.2 0.0 1.9 0.9 0.8 6.1 2.2 1.0 0.1 4.6 0.8 1.5 1.2 0.5 1.3 0.7 2.3 2.6 1.1 0.2 4.0 0.9 3.5 1.3 1.0 0.7 1.5 0.4 2.3 0.8 1.3 1.5 1.9 0.5 1.2 1.1 0.8 4.0 0.8 0.7 6.8 4.2 1.4 0.4 2.8 1.6 0.4 1.5 1.8 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 2.0 7.2 3.1 1.4 1.3 2.1 1.9 2.2 1.1 1.7 3.3 1.0 0.0 3.4 6.8 2.0 0.8 1.0 3.9 1.2 5.9 2.4 3.6 7.9 11.5 1.8 1.8 0.0 2.5 2.6 22.9 1.9 0.8 2.2 0.6 1.1 1.5 0.0 3.2 1.1 4.8 3.9 2.4 4.1 1.4 0.0 6.7 2.5 26.6 2.6 16.8 2.1 21.8 6.1 1.9 1.2 2.7 1.8 1.6 0.0 0.0 1.7 2.9 1.0 2.5 1.9 0.9 11.3 1.5 3.0 1.4 23.4 2.5 2.9 7.6 0.0 1.0 2.4 1.6 2.1 0.9 0.4 2.3 1.8 1.8 12.4 0.6 MAP3K20 "MLK7, MLTK, MLTKalpha, MLTKbeta, MRK, ZAK" ENSG00000091436 "Mitogen-activated protein kinase kinase kinase 20" Q9NYL2 2 173075435-173268015 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 261.9;tongue: 279.7" "Cell type enhanced" "Detected in many" "Adipocytes: 57.5;Alveolar cells type 2: 57.7;Cytotrophoblasts: 52.6;Endometrial stromal cells: 96.7;Granulosa cells: 100.7;Smooth muscle cells: 83.2;Theca cells: 70.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 15.5" "Group enriched" "Detected in many" 5 "dendritic cells: 15.5;monocytes: 9.4" "Cell line enhanced" "Detected in many" "U-138 MG: 176.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017205 Approved Supported Cytosol NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA017205: AB_1858933" "unprognostic (2.90e-2)" "unprognostic (9.99e-3)" "unprognostic (4.63e-3)" "unprognostic (1.98e-1)" "unprognostic (7.63e-2)" "unprognostic (5.02e-2)" "unprognostic (2.34e-2)" "unprognostic (3.89e-3)" "unprognostic (2.83e-2)" "unprognostic (9.27e-2)" "unprognostic (4.54e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (3.41e-6)" "unprognostic (2.34e-1)" "unprognostic (1.86e-1)" "unprognostic (2.23e-1)" "unprognostic (1.19e-2)" 71.0 11.4 9.5 20.5 9.7 4.7 21.4 10.3 8.5 44.9 15.7 65.8 13.0 76.4 18.6 50.0 48.0 31.4 195.7 9.3 12.1 7.5 25.2 22.5 9.8 13.8 14.7 69.5 11.7 49.3 3.8 27.6 11.2 44.0 20.9 2.5 12.4 57.1 261.9 14.1 19.2 75.0 11.1 12.5 31.5 10.6 12.5 11.5 16.4 279.7 10.2 56.1 21.2 9.4 34.6 28.6 22.0 29.1 62.7 92.5 13.8 121.9 94.7 55.9 59.6 19.5 22.2 26.5 31.2 122.5 48.8 22.9 33.1 64.6 124.2 52.0 22.0 43.3 30.5 4.1 24.8 39.3 43.8 74.7 27.2 105.2 164.2 46.3 37.5 28.5 19.8 4.9 36.8 14.8 24.8 19.0 12.2 28.9 16.0 36.2 45.0 0.1 13.6 19.6 12.9 12.4 47.0 11.3 19.7 35.6 12.9 20.9 37.9 176.3 71.4 53.1 27.9 0.1 0.1 5.5 126.2 10.6 18.9 0.2 9.4 0.0 1.0 8.3 1.0 1.6 0.8 1.7 15.5 2.5 0.0 0.8 2.6 0.5 8.2 0.3 0.8 3.4 9.5 9.7 10.3 8.5 9.3 12.1 13.8 14.7 11.2 11.1 12.5 9.4 57.5 38.5 57.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 20.0 44.4 0.0 0.0 7.4 11.0 0.0 52.6 2.3 0.0 1.9 43.9 0.0 36.7 96.7 14.1 0.0 0.0 0.0 27.6 21.9 36.5 0.0 35.6 5.1 100.7 0.0 0.0 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 15.5 0.0 0.0 0.0 0.0 38.6 0.0 0.0 1.4 0.0 0.0 1.9 13.1 0.0 0.0 0.0 83.2 0.0 0.0 0.0 0.0 21.6 3.6 70.5 0.0 0.0 MARCKSL1 "F52, MacMARCKS, MLP, MLP1" ENSG00000175130 "MARCKS like 1" P49006 1 32333839-32336233 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 712.7" "Cell type enhanced" "Detected in many" "monocytes: 941.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 8 "eosinophil: 252.7" "Lineage enriched" "Detected in all" 8 "granulocytes: 252.7" "Cell line enhanced" "Detected in many" "AF22: 1016.3;NTERA-2: 984.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020787, HPA030528" Enhanced Supported "Nucleoplasm,Actin filaments,Cytosol" NA Yes 170000 "Cluster 52: Eosinophils - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 5: NTERA-2 - Transcription" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "Nucleoplasm, Actin filaments" "CAB020787: , HPA030528: AB_2673514" "unprognostic (8.08e-2)" "unprognostic (1.28e-1)" "unprognostic (1.11e-1)" "unprognostic (1.04e-2)" "unprognostic (1.38e-1)" "unprognostic (3.16e-3)" "prognostic unfavorable (1.78e-6)" "unprognostic (3.65e-1)" "unprognostic (1.72e-1)" "unprognostic (8.41e-3)" "unprognostic (2.91e-1)" "unprognostic (1.76e-2)" "prognostic unfavorable (1.20e-4)" "unprognostic (1.50e-1)" "unprognostic (8.16e-3)" "unprognostic (1.08e-1)" "unprognostic (3.22e-2)" 63.4 59.9 363.5 82.1 510.3 50.1 102.9 540.1 438.2 81.2 206.4 108.1 61.8 93.4 155.8 15.1 72.2 97.2 55.0 343.0 408.0 51.1 38.7 40.0 176.0 631.5 504.7 358.0 23.7 6.5 22.9 42.9 534.9 84.7 116.5 37.9 75.9 49.9 8.7 28.3 56.1 42.7 467.9 63.1 132.8 139.2 466.4 166.0 110.3 11.0 199.5 77.8 27.1 712.7 82.9 73.3 1016.3 418.6 22.5 8.3 181.0 34.0 21.2 99.9 66.0 176.0 59.9 185.7 124.4 23.2 0.3 43.0 333.1 3.8 73.3 4.5 246.5 10.0 27.0 392.4 68.7 48.8 0.9 114.8 13.7 75.0 2.1 154.2 295.0 312.6 291.5 2.2 135.7 197.5 613.5 205.9 984.3 267.4 168.1 754.8 109.4 87.7 152.1 163.1 629.0 597.8 178.8 194.2 587.8 411.9 135.4 85.8 87.8 41.8 241.3 3.9 66.1 27.8 2.3 489.8 4.7 73.6 225.7 3.1 4.0 252.7 3.8 23.1 1.4 20.0 7.4 4.9 6.6 27.7 15.3 6.4 18.2 1.1 30.3 9.0 4.8 4.9 363.5 510.3 540.1 438.2 343.0 408.0 631.5 504.7 534.9 467.9 466.4 712.7 242.5 0.0 1.3 27.1 191.1 93.7 114.7 43.5 40.5 27.7 465.7 385.8 8.5 178.7 68.8 60.7 6.2 16.1 110.1 194.1 82.2 389.7 37.4 68.7 190.3 326.9 746.2 74.4 4.2 307.2 116.4 124.3 246.2 115.2 22.3 378.6 462.3 5.3 21.2 10.1 21.9 514.2 236.0 61.0 365.3 66.7 613.3 82.0 300.6 9.4 941.4 464.3 46.4 93.0 428.3 751.6 292.8 641.3 39.5 418.8 30.2 9.8 15.6 14.8 131.5 40.3 210.0 14.8 102.7 22.5 83.1 13.4 89.8 172.0 447.1 586.9 MASTL "FLJ14813, Gwl, THC2" ENSG00000120539 "Microtubule associated serine/threonine kinase like" Q96GX5 10 27154824-27187953 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 24.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027175, HPA054273" Approved Enhanced Nucleoplasm NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA027175: AB_1853591, HPA054273: AB_2682433" "unprognostic (4.10e-2)" "unprognostic (6.89e-2)" "unprognostic (1.22e-2)" "unprognostic (3.14e-3)" "unprognostic (3.67e-1)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.52e-6)" "unprognostic (2.19e-2)" "unprognostic (4.00e-2)" "unprognostic (4.05e-2)" "prognostic unfavorable (4.81e-5)" "unprognostic (3.78e-2)" "prognostic unfavorable (1.71e-6)" "unprognostic (1.55e-3)" "unprognostic (2.27e-1)" "unprognostic (2.66e-1)" "unprognostic (1.79e-1)" 5.0 3.9 1.7 6.2 1.9 18.7 5.3 2.3 2.3 3.8 2.1 4.1 4.4 3.9 4.5 5.9 3.0 3.9 2.5 1.9 2.0 3.9 4.9 4.0 8.9 2.0 2.0 3.4 3.3 6.0 3.1 6.5 2.1 3.1 5.2 2.7 4.1 3.0 2.3 6.0 4.3 4.5 1.6 4.6 4.7 6.5 2.0 10.4 4.7 2.2 7.1 4.5 4.3 2.3 29.4 22.0 43.8 15.5 6.2 9.1 25.4 43.3 18.0 68.4 83.8 26.7 27.2 22.4 16.1 18.4 33.5 26.8 27.9 16.0 48.2 20.2 26.5 26.9 14.5 15.5 3.8 10.4 19.8 5.6 7.5 41.6 7.9 9.0 14.7 18.2 21.1 49.9 41.5 17.9 34.8 11.2 32.0 15.9 8.9 22.2 71.9 18.9 17.4 10.6 19.2 26.8 26.0 17.6 19.1 28.1 17.2 21.4 12.6 17.0 36.3 44.0 37.4 5.9 10.3 34.7 18.3 31.1 14.8 0.2 1.8 1.7 0.7 1.7 1.1 1.1 0.9 0.7 1.0 1.6 0.9 0.8 2.3 1.0 1.8 1.1 1.6 0.8 1.7 1.9 2.3 2.3 1.9 2.0 2.0 2.0 2.1 1.6 2.0 2.3 4.3 6.4 7.8 2.6 7.4 11.0 4.9 4.4 4.0 1.7 4.2 4.8 3.0 2.8 7.0 1.8 0.0 8.6 10.1 7.0 0.0 4.0 3.0 9.7 5.3 4.6 4.2 7.8 4.3 2.5 24.9 7.3 6.1 17.9 12.7 6.9 2.5 2.5 5.8 3.3 4.3 3.7 4.1 7.8 19.3 1.7 3.1 11.3 0.0 3.7 5.1 1.8 3.1 3.5 4.9 4.4 2.9 2.6 7.1 5.0 2.8 1.9 4.0 1.0 0.0 3.8 5.3 14.9 14.1 10.9 9.9 6.2 11.6 5.4 4.5 6.6 MB21D2 C3orf59 ENSG00000180611 "Mab-21 domain containing 2" Q8IYB1 3 192796815-192917856 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 63.8;Inhibitory neurons: 53.0;Langerhans cells: 85.0;Oligodendrocyte precursor cells: 68.9;Syncytiotrophoblasts: 110.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 4.2;T-reg: 3.9" "Lineage enriched" "Detected in single" 9 "T-cells: 4.2" "Cell line enhanced" "Detected in many" "HDLM-2: 114.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044026 Approved Approved Cytosol NA Yes "Cluster 13: T-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 44: HDLM-2 - Immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA044026: AB_10962840" "unprognostic (3.52e-2)" "unprognostic (1.02e-1)" "unprognostic (3.06e-1)" "prognostic unfavorable (3.74e-5)" "unprognostic (2.42e-2)" "prognostic unfavorable (9.94e-4)" "unprognostic (2.76e-2)" "unprognostic (3.50e-2)" "unprognostic (1.53e-1)" "unprognostic (2.46e-1)" "unprognostic (2.84e-2)" "unprognostic (1.57e-1)" "unprognostic (1.30e-3)" "unprognostic (5.94e-3)" "unprognostic (1.95e-1)" "unprognostic (3.80e-2)" "unprognostic (3.28e-2)" 3.7 4.2 2.5 3.2 2.8 1.3 3.4 3.3 3.1 2.8 1.6 3.0 8.8 5.1 1.9 2.0 3.6 4.7 4.0 2.8 2.3 4.2 1.5 3.6 1.2 2.1 2.0 4.1 1.9 2.3 3.5 13.3 1.8 1.9 2.9 2.0 1.5 1.9 2.7 4.7 9.3 5.6 1.5 2.2 3.5 7.1 1.9 1.4 1.7 1.6 1.7 8.8 2.4 2.3 26.6 3.7 6.3 19.0 3.9 5.8 11.2 18.8 17.5 33.4 19.9 17.0 4.2 0.0 11.0 46.6 13.8 11.5 14.6 4.8 36.2 114.8 8.1 3.3 1.8 2.0 7.4 0.4 1.6 7.6 7.4 9.4 5.8 2.7 6.6 3.3 0.2 1.5 5.8 19.8 0.3 0.0 13.1 14.4 45.9 0.6 10.5 5.6 7.8 15.1 9.8 5.0 4.1 12.8 1.9 12.9 19.9 0.4 2.1 6.3 18.4 11.1 36.3 48.1 41.0 0.0 4.4 4.0 8.6 0.0 0.2 0.0 0.2 0.3 1.9 0.1 4.2 1.0 0.4 0.0 2.6 0.7 0.0 0.0 0.0 0.0 3.9 0.9 2.5 2.8 3.3 3.1 2.8 2.3 2.1 2.0 1.8 1.5 1.9 2.3 2.9 6.4 0.5 16.6 1.2 9.2 0.9 2.0 1.2 10.9 4.6 3.2 1.8 1.5 3.2 0.0 2.1 63.8 0.3 2.4 0.0 6.5 0.2 12.4 2.0 7.7 10.2 0.0 28.6 0.2 9.5 5.9 1.5 15.9 0.0 5.8 9.7 0.2 5.6 8.4 53.0 2.8 4.1 3.8 85.0 1.4 3.1 10.4 14.2 17.8 13.4 1.1 0.0 68.9 30.6 2.2 6.1 6.0 4.2 0.8 15.4 9.6 2.8 1.3 13.1 3.3 4.5 1.8 16.5 1.8 8.7 110.4 3.3 5.4 3.7 2.6 MCM10 "CNA43, DNA43, PRO2249" ENSG00000065328 "Minichromosome maintenance 10 replication initiation factor" Q7L590 10 13161558-13211110 "Predicted intracellular proteins" "DNA damage, DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 9.2;lymphoid tissue: 8.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 11.8;Erythroid cells: 23.5;Extravillous trophoblasts: 20.9;Plasma cells: 15.3;Spermatocytes: 15.8;Spermatogonia: 12.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045899, HPA071952" Approved Supported Nucleoplasm,Nucleoli Yes Yes "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli" "HPA045899: AB_10960529, HPA071952: AB_2686477" "unprognostic (9.76e-3)" "unprognostic (1.60e-1)" "unprognostic (2.31e-1)" "unprognostic (2.29e-3)" "unprognostic (1.41e-1)" "unprognostic (6.58e-3)" "unprognostic (1.78e-8)" "unprognostic (2.42e-3)" "unprognostic (3.51e-2)" "unprognostic (6.26e-2)" "unprognostic (2.78e-4)" "unprognostic (7.81e-2)" "unprognostic (0.00e+0)" "unprognostic (8.87e-2)" "unprognostic (1.29e-1)" "unprognostic (9.73e-2)" "unprognostic (1.05e-1)" 1.2 0.1 0.0 3.3 0.1 9.2 0.8 0.1 0.2 0.4 0.1 1.7 1.5 0.4 0.1 1.9 0.2 0.2 0.1 0.0 0.0 0.1 0.7 0.3 4.8 0.0 0.1 0.2 0.1 0.2 0.1 2.1 0.1 0.1 2.2 0.1 0.3 0.0 0.5 1.1 1.2 0.8 0.0 1.0 0.8 1.5 0.2 8.1 0.3 0.1 4.5 0.6 0.6 0.1 38.0 42.0 48.6 36.9 1.6 2.9 21.2 38.7 5.9 42.7 44.0 41.3 26.4 56.7 17.1 9.9 15.7 43.3 69.0 22.8 39.2 29.7 32.9 70.9 17.6 27.7 0.0 36.6 30.8 0.6 0.8 43.3 4.0 3.5 14.0 45.0 85.2 37.6 23.4 34.0 87.7 15.7 28.9 36.3 10.3 68.3 43.0 34.6 9.8 13.7 9.7 36.6 31.3 22.0 5.9 25.2 27.7 24.9 8.6 27.0 50.3 41.0 42.4 11.7 49.0 74.3 17.2 39.6 21.5 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.9 0.3 0.1 0.1 0.7 0.4 0.1 0.1 0.0 0.4 0.4 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 1.7 0.0 0.0 0.0 1.8 1.7 0.4 0.8 0.0 0.0 0.8 0.5 2.4 0.0 0.8 0.0 0.0 11.8 0.8 2.4 0.0 0.4 1.0 0.3 1.2 1.4 0.0 23.5 0.4 0.2 20.9 1.8 1.1 1.0 0.0 7.2 0.0 0.2 5.3 0.0 0.4 1.2 2.0 0.6 0.4 1.3 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.1 0.4 15.3 0.2 0.2 0.0 0.0 0.0 0.0 0.4 6.4 15.8 12.9 3.6 0.4 3.4 1.2 0.8 3.1 0.4 MCM2 "BM28, CCNL1, cdc19, CDCL1, D3S3194, DFNA70, KIAA0030" ENSG00000073111 "Minichromosome maintenance complex component 2" P49736 3 127598410-127622436 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 67.7;lymphoid tissue: 37.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 63.3;Erythroid cells: 65.6;Extravillous trophoblasts: 28.8;Spermatogonia: 25.9;Syncytiotrophoblasts: 33.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "CAB000303, HPA031450, HPA031495, HPA031496" Enhanced Enhanced Nucleoplasm Yes Yes 120000 "Cluster 43: B-cells - Humoral immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB000303: AB_322519, HPA031450: , HPA031495: AB_2673904, HPA031496: AB_2673905" "unprognostic (2.43e-1)" "prognostic favorable (4.66e-4)" "unprognostic (4.44e-2)" "unprognostic (3.12e-3)" "unprognostic (1.68e-1)" "unprognostic (2.25e-2)" "prognostic unfavorable (1.51e-7)" "unprognostic (8.43e-3)" "unprognostic (1.92e-2)" "unprognostic (1.79e-1)" "unprognostic (1.41e-3)" "unprognostic (1.21e-2)" "unprognostic (1.16e-2)" "unprognostic (8.16e-3)" "unprognostic (1.56e-1)" "unprognostic (3.29e-2)" "unprognostic (2.82e-1)" 3.1 3.4 2.0 16.4 1.9 67.7 6.2 2.5 1.9 5.3 0.6 9.2 8.1 5.0 2.4 11.0 7.6 2.5 6.4 1.9 1.8 3.4 6.3 3.4 26.8 2.3 1.9 6.4 3.0 3.7 2.4 17.0 2.6 5.0 10.2 3.5 4.7 2.8 9.4 10.6 8.6 5.3 2.0 9.6 5.7 12.3 2.0 37.6 4.8 5.8 26.0 4.2 5.4 2.4 133.6 110.3 122.4 102.1 7.0 14.4 110.5 65.2 42.3 129.9 146.9 177.7 84.7 136.0 65.2 32.3 113.6 105.6 204.8 76.1 79.1 127.2 127.1 227.4 134.8 131.1 4.4 214.3 102.4 8.2 8.4 86.1 13.1 15.3 40.6 160.7 116.0 123.7 47.4 169.0 229.0 156.2 172.5 108.3 90.7 242.4 165.1 203.3 26.9 97.9 143.0 106.8 175.8 48.9 16.7 45.7 111.9 165.3 20.3 104.2 87.9 128.4 91.7 127.1 163.5 362.6 73.2 159.7 41.0 0.0 0.6 0.3 4.4 1.4 5.5 9.7 3.9 5.4 2.9 8.1 3.6 4.7 0.9 6.5 0.4 3.7 11.2 3.5 2.0 1.9 2.5 1.9 1.9 1.8 2.3 1.9 2.6 2.0 2.0 2.4 1.2 3.2 2.0 0.7 8.5 4.6 2.6 4.6 2.2 2.5 4.1 5.3 8.3 0.0 3.9 0.0 0.0 63.3 1.8 4.8 0.0 5.3 0.9 5.2 3.5 2.9 3.6 65.6 0.3 1.9 28.8 4.2 6.6 4.8 1.3 18.8 1.4 1.7 18.2 0.0 0.4 8.2 0.0 1.6 3.2 0.7 1.8 2.7 1.8 0.0 9.2 2.1 0.0 0.0 0.7 2.1 1.7 1.5 20.5 0.8 1.1 0.8 7.4 2.1 0.0 2.6 4.1 8.1 25.9 7.1 3.0 33.5 6.3 3.8 13.8 2.3 MCM3 ENSG00000112118 "Minichromosome maintenance complex component 3" P25205 6 52264014-52284881 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 122.7;Erythroid cells: 92.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002162, HPA004789, HPA004790" Supported Supported Nucleoplasm NA Yes 150000 "Cluster 35: T-regs - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB002162: AB_564115, HPA004789: AB_1079336, HPA004790: AB_1079335" "unprognostic (9.14e-2)" "prognostic favorable (1.89e-4)" "unprognostic (2.37e-1)" "unprognostic (1.53e-2)" "unprognostic (2.14e-1)" "unprognostic (5.48e-3)" "prognostic unfavorable (1.40e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (4.40e-5)" "unprognostic (1.01e-3)" "unprognostic (2.96e-2)" "unprognostic (1.15e-1)" "unprognostic (8.35e-2)" "unprognostic (1.16e-2)" "unprognostic (1.00e-1)" "prognostic favorable (3.13e-5)" "unprognostic (1.34e-2)" 24.3 15.9 12.8 41.5 13.6 55.5 29.1 13.7 13.7 27.5 13.4 32.9 19.6 30.8 23.8 33.4 29.2 16.4 25.4 11.9 12.7 27.5 18.8 21.4 68.8 14.1 13.6 31.9 17.0 28.9 10.8 40.0 14.1 19.7 39.3 19.3 19.2 30.7 16.0 32.2 29.3 37.0 14.5 31.3 24.1 21.1 14.0 81.1 18.3 17.7 78.5 28.1 24.5 13.9 187.9 121.7 208.0 196.9 43.9 39.4 136.1 135.8 103.7 226.6 230.3 251.6 99.2 202.8 132.5 79.7 147.8 145.4 277.4 165.9 226.9 230.0 261.4 383.6 233.2 358.2 11.8 381.7 150.8 23.7 38.1 166.6 46.2 55.6 117.3 240.4 318.1 452.9 118.3 123.8 386.9 293.5 173.1 369.8 84.8 338.3 317.0 271.2 101.1 195.8 210.3 160.5 142.2 81.1 125.3 289.4 159.7 266.9 60.5 153.5 163.6 160.8 206.4 132.9 163.5 356.4 132.2 323.8 184.0 30.5 18.3 27.3 50.0 31.3 42.8 47.7 49.9 50.3 30.0 41.2 47.6 51.2 2.6 55.0 18.3 19.0 71.6 46.9 12.8 13.6 13.7 13.7 11.9 12.7 14.1 13.6 14.1 14.5 14.0 13.9 24.3 22.4 12.3 3.3 26.4 19.2 20.0 24.9 12.5 16.1 14.1 17.1 19.9 7.2 19.2 22.0 4.2 122.7 18.6 10.9 13.7 30.9 1.1 9.6 16.7 30.9 7.3 92.6 2.5 20.2 63.6 22.3 15.8 15.1 37.4 48.3 15.0 10.5 36.0 0.0 2.1 20.4 8.2 10.1 7.5 3.6 27.1 12.1 7.2 8.4 12.5 17.8 34.0 2.5 6.1 17.3 10.5 21.1 37.6 10.9 7.3 7.5 17.0 16.0 6.6 16.8 27.9 22.5 64.0 24.5 10.1 27.4 26.0 19.0 37.1 13.9 MCM4 "CDC21, CDC54, hCdc21, MGC33310, P1-Cdc21" ENSG00000104738 "Minichromosome maintenance complex component 4" P33991 8 47960185-47978160 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 63.2" "Cell type enhanced" "Detected in many" "Early spermatids: 153.2;Erythroid cells: 60.8;Late spermatids: 77.9;Spermatocytes: 65.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004497, HPA004873, HPA031052" Enhanced Enhanced Nucleoplasm NA Yes 140000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB004497: AB_627916, HPA004873: AB_1079337, HPA031052: AB_2673712" "unprognostic (4.55e-2)" "unprognostic (3.16e-3)" "prognostic favorable (2.19e-4)" "prognostic unfavorable (2.84e-5)" "unprognostic (7.71e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (1.23e-4)" "unprognostic (1.12e-3)" "prognostic unfavorable (1.15e-4)" "unprognostic (2.65e-2)" "prognostic unfavorable (2.38e-4)" "unprognostic (5.16e-2)" "prognostic unfavorable (2.61e-4)" "unprognostic (3.53e-2)" "unprognostic (2.90e-1)" "unprognostic (1.70e-2)" "unprognostic (1.40e-1)" 6.5 8.8 4.8 21.7 4.8 63.2 16.0 5.7 5.2 7.7 1.8 17.7 13.3 6.9 4.6 22.4 9.7 5.6 14.5 5.2 3.5 8.2 9.2 6.3 38.7 3.6 4.2 7.1 5.5 7.7 4.1 18.3 3.9 5.6 21.3 12.3 8.8 4.9 13.4 24.2 16.7 9.2 4.2 8.1 10.6 41.6 4.8 47.0 6.5 15.8 41.8 11.8 10.9 5.2 184.0 139.6 188.1 83.2 20.7 36.6 102.8 122.6 99.8 178.5 190.3 156.6 181.1 229.8 70.3 72.1 119.2 143.2 278.7 128.2 199.8 64.2 190.4 371.8 133.3 169.2 5.4 189.7 82.0 20.3 24.1 147.8 54.3 28.6 72.0 136.8 216.2 167.0 129.9 155.6 435.5 141.5 241.2 246.5 54.2 266.6 159.6 139.2 64.9 168.1 209.0 97.8 325.6 133.6 46.3 117.7 154.9 110.5 45.1 138.1 125.4 144.5 131.9 54.7 104.6 347.2 114.8 185.7 131.5 2.3 1.8 1.1 4.0 3.1 2.0 3.9 3.8 5.4 3.9 1.6 3.3 2.7 0.1 4.1 3.5 1.5 10.2 3.6 4.8 4.8 5.7 5.2 5.2 3.5 3.6 4.2 3.9 4.2 4.8 5.2 3.3 0.0 6.3 3.3 6.5 21.7 11.1 9.0 13.6 12.2 9.0 7.7 25.1 1.5 8.4 5.5 10.4 36.7 5.8 12.1 3.9 8.0 153.2 11.0 7.9 6.7 6.7 60.8 5.0 6.0 40.2 10.6 11.2 13.4 1.3 24.9 2.2 3.2 12.3 16.8 5.7 13.9 4.1 2.9 6.5 77.9 5.3 7.9 3.6 1.9 2.4 7.0 3.1 4.0 2.9 4.5 4.8 3.0 22.3 7.7 5.6 3.0 13.1 16.7 0.0 9.5 11.4 65.8 39.9 19.1 19.0 29.8 9.0 11.7 26.2 9.7 MCM5 CDC46 ENSG00000100297 "Minichromosome maintenance complex component 5" P33992 22 35400134-35425431 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 138.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 147.8;Erythroid cells: 96.6;monocytes: 137.7;Syncytiotrophoblasts: 82.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000101, HPA000845, HPA052880" Enhanced Enhanced Nucleoplasm Yes Yes 44000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB000101: AB_2235163, HPA000845: AB_1079338, HPA052880: AB_2681979" "unprognostic (6.71e-2)" "prognostic favorable (2.81e-6)" "unprognostic (5.29e-3)" "unprognostic (7.94e-2)" "unprognostic (1.83e-2)" "unprognostic (1.46e-2)" "prognostic unfavorable (1.78e-4)" "prognostic unfavorable (3.95e-4)" "unprognostic (1.29e-1)" "unprognostic (3.34e-2)" "unprognostic (1.37e-1)" "unprognostic (8.07e-2)" "prognostic unfavorable (3.58e-5)" "unprognostic (3.26e-2)" "unprognostic (1.01e-1)" "unprognostic (1.77e-3)" "unprognostic (1.53e-1)" 15.2 7.1 5.8 49.1 10.4 138.7 14.4 8.3 7.4 14.5 5.8 20.2 19.6 16.3 3.3 25.1 13.7 9.6 8.9 5.8 7.0 9.1 14.9 14.8 70.1 10.3 7.7 25.6 12.6 10.3 5.3 25.2 9.6 10.2 16.7 2.3 13.9 9.6 13.3 17.6 28.3 12.2 8.1 47.3 17.9 20.6 9.0 58.9 12.1 8.0 53.6 12.7 15.6 12.3 213.0 147.5 115.7 118.8 11.0 22.2 100.6 138.1 71.2 199.4 188.3 98.9 102.4 137.9 78.8 70.5 83.6 103.8 116.0 108.3 64.4 112.7 212.6 198.3 141.5 203.7 3.9 414.0 172.4 12.3 9.7 120.0 32.4 18.4 88.7 124.5 124.0 201.2 76.9 172.7 341.8 137.9 154.9 143.4 86.7 379.6 164.8 173.0 39.4 120.1 88.2 94.8 188.3 75.4 41.8 60.9 78.8 155.6 54.1 201.3 153.1 127.2 145.4 111.9 150.2 265.2 130.9 153.5 157.6 66.5 59.8 43.4 49.5 69.6 35.8 127.5 43.1 53.1 77.8 106.1 34.0 39.0 28.4 65.5 81.2 88.8 96.6 77.1 5.8 10.4 8.3 7.4 5.8 7.0 10.3 7.7 9.6 8.1 9.0 12.3 8.1 6.4 7.3 1.3 49.5 10.6 13.6 12.1 8.6 1.5 9.2 10.8 3.5 8.6 6.0 7.3 0.0 147.8 30.4 12.0 5.9 19.8 2.8 6.2 4.1 11.8 3.5 96.6 0.3 12.7 77.1 11.2 18.8 9.0 15.2 65.7 13.2 5.3 53.1 1.7 0.4 16.6 4.1 24.0 29.4 5.1 10.8 28.4 7.2 7.5 137.7 5.7 13.4 3.0 6.0 11.0 8.6 6.0 49.3 4.0 6.5 5.7 4.8 3.7 19.7 8.8 14.5 16.1 58.8 14.9 6.3 82.2 19.4 8.5 34.6 9.8 MCM6 Mis5 ENSG00000076003 "Minichromosome maintenance complex component 6" Q14566 2 135839626-135876443 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 48.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 40.1;Erythroid cells: 50.5;Spermatogonia: 40.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004818, CAB009577" Enhanced Enhanced Nucleoplasm NA Yes 33000 "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB009577: AB_2266309, HPA004818: AB_1079339" "unprognostic (6.73e-2)" "unprognostic (6.68e-3)" "unprognostic (1.22e-3)" "unprognostic (3.60e-3)" "unprognostic (8.98e-2)" "unprognostic (4.34e-2)" "prognostic unfavorable (5.70e-7)" "unprognostic (1.71e-2)" "prognostic unfavorable (1.09e-5)" "unprognostic (2.36e-2)" "unprognostic (1.36e-2)" "unprognostic (3.53e-2)" "prognostic unfavorable (8.29e-12)" "unprognostic (2.84e-1)" "unprognostic (9.02e-2)" "unprognostic (7.42e-2)" "unprognostic (1.68e-1)" 10.0 5.3 4.7 20.7 5.1 35.6 11.6 6.3 6.4 10.2 3.5 12.8 11.7 10.0 5.1 11.1 7.9 6.8 5.3 5.0 5.1 6.4 9.5 7.8 34.4 4.4 4.6 11.3 3.9 4.6 3.0 12.6 4.7 6.9 15.6 3.2 6.0 8.3 8.1 10.5 13.2 11.8 4.8 9.9 8.2 14.6 5.4 48.5 4.5 7.6 38.0 9.6 8.9 5.5 104.4 62.8 133.8 85.7 28.2 36.5 52.3 73.9 55.8 84.3 93.0 129.3 77.7 181.0 52.9 54.0 36.9 60.4 136.7 67.6 89.5 93.6 94.4 179.9 85.0 40.9 13.1 218.4 76.9 21.7 8.6 61.7 18.9 16.8 58.1 139.8 130.8 147.9 62.6 106.3 268.6 159.6 120.9 91.3 62.1 131.1 159.9 165.7 42.3 90.3 83.7 71.3 97.6 45.9 47.0 95.2 53.1 135.4 29.0 58.3 48.0 63.4 56.8 87.8 153.7 234.2 81.4 163.5 70.9 9.2 1.6 1.1 8.1 4.7 7.6 6.1 11.1 9.9 5.2 4.7 9.9 12.4 0.9 9.1 4.5 10.6 16.1 6.3 4.7 5.1 6.3 6.4 5.0 5.1 4.4 4.6 4.7 4.8 5.4 5.5 6.4 0.0 2.7 3.9 10.3 6.6 4.1 5.4 7.4 3.3 4.2 5.8 4.6 2.8 5.4 3.7 0.0 40.1 28.2 3.0 0.0 7.2 3.2 2.5 8.9 8.3 2.4 50.5 3.5 6.6 28.0 13.3 9.7 7.1 9.5 27.2 8.9 3.0 24.4 3.3 3.4 11.7 0.0 4.7 3.5 2.1 9.3 9.6 5.4 3.7 3.2 2.4 4.1 2.0 2.8 3.9 4.9 17.0 27.6 1.6 2.4 0.9 3.0 0.5 0.0 7.2 10.0 26.6 40.4 10.2 4.1 10.7 22.0 9.6 15.4 2.7 MCM7 "CDC47, MCM2, PPP1R104" ENSG00000166508 "Minichromosome maintenance complex component 7" P33993 7 100092728-100101940 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 180.8;lymphoid tissue: 156.4" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 132.9;Erythroid cells: 173.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002163, HPA003898, CAB016312" Enhanced Enhanced Nucleoplasm NA Yes 150000 "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB002163: AB_564113, CAB016312: AB_627235, HPA003898: AB_1853632" "unprognostic (1.87e-1)" "prognostic favorable (1.28e-4)" "unprognostic (1.36e-1)" "unprognostic (5.20e-2)" "unprognostic (1.94e-1)" "unprognostic (7.03e-2)" "prognostic unfavorable (2.18e-4)" "unprognostic (2.08e-2)" "unprognostic (5.79e-3)" "unprognostic (2.16e-2)" "unprognostic (2.42e-1)" "unprognostic (9.34e-3)" "unprognostic (3.83e-2)" "unprognostic (5.41e-2)" "unprognostic (1.76e-1)" "unprognostic (1.32e-2)" "unprognostic (2.38e-1)" 22.9 14.2 56.4 50.2 61.7 180.8 32.0 51.4 70.4 17.4 45.8 45.3 38.7 29.7 13.1 31.2 25.6 18.2 17.0 48.8 50.5 13.7 26.3 23.0 82.4 58.5 59.8 37.0 24.1 15.1 8.9 35.0 55.1 20.4 50.8 10.6 21.3 22.2 25.7 44.9 41.3 32.3 55.1 29.4 27.4 49.4 55.6 156.4 20.4 28.5 88.5 21.6 11.9 60.8 310.1 359.5 399.9 306.7 28.7 35.5 214.4 195.7 165.5 374.9 407.7 281.9 335.2 469.2 184.6 112.0 321.6 252.5 439.3 241.6 303.9 238.6 498.1 274.7 251.9 248.9 18.9 553.6 226.2 30.1 43.4 306.9 179.6 61.8 154.0 295.1 542.2 444.6 200.8 786.2 940.1 442.9 361.9 295.2 236.4 572.5 517.7 651.6 92.3 221.5 253.4 397.0 264.9 294.3 104.9 217.9 126.2 314.4 81.0 198.1 346.7 379.8 411.1 200.3 311.8 875.0 135.9 463.1 354.3 3.7 4.0 4.3 14.1 7.5 10.9 9.1 10.3 13.2 9.3 15.0 11.2 10.5 1.4 15.9 13.3 11.3 17.2 11.6 56.4 61.7 51.4 70.4 48.8 50.5 58.5 59.8 55.1 55.1 55.6 60.8 23.2 9.6 17.9 6.2 34.5 46.7 28.5 25.7 37.0 9.4 30.8 36.3 9.6 11.5 13.3 3.7 14.6 132.9 32.5 42.3 9.8 28.2 54.7 11.8 16.3 23.8 17.4 173.6 4.0 26.2 102.7 22.8 40.8 19.8 24.1 67.3 10.4 10.3 40.4 6.7 4.0 48.8 18.3 10.4 22.2 32.0 21.1 17.6 19.6 3.7 14.1 11.1 18.6 12.1 11.7 16.7 22.8 15.4 59.8 20.8 19.0 11.5 18.0 12.5 13.1 30.7 46.0 90.0 79.8 41.3 35.4 72.0 29.4 14.9 79.0 22.9 MELK KIAA0175 ENSG00000165304 "Maternal embryonic leucine zipper kinase" Q14680 9 36572862-36677683 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.0;lymphoid tissue: 21.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 16.1;Erythroid cells: 15.2;Extravillous trophoblasts: 44.1;Spermatocytes: 23.2;Spermatogonia: 21.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 4 "T-reg: 1.7" "Lineage enriched" "Detected in single" 4 "T-cells: 1.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA017214 Uncertain NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" "HPA017214: AB_1853798" "unprognostic (5.03e-2)" "unprognostic (9.57e-2)" "unprognostic (2.27e-2)" "unprognostic (3.42e-3)" "unprognostic (2.16e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.91e-7)" "prognostic unfavorable (3.99e-4)" "unprognostic (1.26e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (4.58e-4)" "unprognostic (4.69e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (8.86e-3)" "unprognostic (1.37e-1)" "unprognostic (2.40e-1)" "unprognostic (1.35e-1)" 0.9 0.5 0.0 5.7 0.0 10.0 1.4 0.0 0.1 1.3 0.0 6.8 5.2 1.0 0.0 7.9 0.3 0.6 0.2 0.0 0.0 0.3 0.7 0.9 10.0 0.0 0.1 0.2 0.3 0.1 0.0 5.3 0.1 0.3 8.5 0.0 1.2 0.1 0.0 3.4 4.4 2.4 0.0 2.0 3.2 9.2 0.3 21.0 0.3 0.1 11.7 1.7 2.3 0.0 123.4 62.1 81.6 48.5 11.1 18.8 47.1 88.8 62.2 121.5 148.2 47.8 47.3 40.9 27.8 43.8 106.5 41.0 71.7 55.5 133.1 112.3 28.6 32.0 69.1 48.1 4.3 50.2 39.0 6.9 9.8 93.9 53.0 15.6 62.2 61.9 41.7 63.2 100.9 40.9 63.1 23.4 65.1 55.1 47.9 57.4 54.9 25.8 37.7 40.7 55.1 40.8 47.4 45.3 28.6 45.2 38.0 23.7 30.8 65.4 81.8 56.1 82.3 12.3 47.9 60.7 41.2 36.8 91.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 1.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.7 1.9 4.6 0.9 3.5 0.0 0.0 0.9 0.8 0.4 0.0 2.0 0.0 0.0 16.1 0.7 4.5 0.0 1.1 2.8 2.9 1.4 1.3 0.0 15.2 0.8 1.1 44.1 3.3 4.6 2.1 0.0 7.8 1.4 0.7 10.1 0.0 0.7 4.7 4.1 1.6 3.0 2.7 1.2 1.9 0.0 0.0 3.1 0.0 2.1 1.0 0.4 1.7 2.7 0.0 10.2 0.5 0.6 0.1 2.0 0.0 0.0 0.0 3.7 23.2 21.3 9.3 1.7 8.9 2.7 0.7 8.9 2.3 MEPCE "BCDIN3, FLJ20257" ENSG00000146834 "Methylphosphate capping enzyme" Q7L2J0 7 100428790-100434118 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026384, HPA051587" Supported Approved "Nucleoplasm,Cell Junctions" NA Yes "Cluster 26: Non-specific - Mitochondria" "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Cell Junctions" "CAB026384: , HPA051587: AB_2681544" "unprognostic (8.59e-2)" "unprognostic (1.23e-2)" "unprognostic (3.77e-2)" "prognostic unfavorable (6.01e-6)" "unprognostic (1.09e-1)" "unprognostic (1.53e-2)" "unprognostic (3.83e-2)" "unprognostic (2.19e-1)" "unprognostic (1.69e-2)" "unprognostic (2.95e-1)" "unprognostic (1.65e-3)" "unprognostic (1.09e-1)" "prognostic favorable (1.01e-10)" "unprognostic (9.66e-2)" "unprognostic (9.31e-2)" "unprognostic (4.57e-1)" "unprognostic (9.50e-3)" 26.4 41.0 27.5 19.4 28.3 28.3 24.2 30.4 31.5 26.1 23.6 25.8 18.5 28.8 27.8 27.5 27.0 19.4 26.8 26.7 27.0 37.0 36.9 21.9 29.0 27.6 27.3 36.0 22.5 35.0 23.6 20.9 27.4 26.5 12.9 9.9 24.9 20.7 38.5 34.5 27.2 18.0 26.8 56.6 24.6 79.8 28.0 28.1 36.5 31.5 24.2 28.3 21.9 28.2 42.6 53.6 38.9 41.9 36.8 36.7 29.1 46.4 66.5 48.7 37.4 43.8 60.1 87.1 75.5 29.1 38.5 38.4 43.0 34.9 32.0 39.4 49.4 45.1 41.5 33.3 30.9 58.0 53.0 38.2 40.9 55.7 70.0 26.5 41.1 27.4 90.6 62.2 47.2 155.6 66.3 129.8 72.1 35.0 58.9 53.0 31.5 79.1 32.7 25.6 58.5 50.6 72.5 139.1 49.1 19.3 35.6 52.1 36.2 81.5 63.5 55.9 62.0 41.0 42.4 96.3 45.8 71.1 72.9 2.6 2.6 3.7 3.8 2.3 4.6 6.2 4.4 4.2 3.3 6.6 6.2 5.5 6.4 5.9 1.9 6.3 4.5 7.5 27.5 28.3 30.4 31.5 26.7 27.0 27.6 27.3 27.4 26.8 28.0 28.2 34.2 9.6 18.9 5.5 33.8 30.2 17.3 7.1 19.9 9.9 30.2 21.6 25.6 20.0 7.8 22.0 8.4 15.8 34.3 32.2 15.6 10.3 29.6 18.3 13.1 21.7 10.7 9.9 2.8 12.0 8.5 17.3 54.6 18.8 18.3 14.5 28.9 22.1 12.7 11.8 2.6 26.1 8.2 26.7 16.9 66.5 17.4 32.9 8.8 7.5 18.1 19.4 15.5 2.5 2.7 10.4 23.6 15.4 14.9 15.6 39.9 14.4 10.4 9.5 6.6 35.0 17.9 44.8 15.1 22.3 25.1 21.2 25.0 19.5 20.3 9.9 METTL4 "FLJ23017, HsT661" ENSG00000101574 "Methyltransferase like 4" Q8N3J2 18 2537525-2571509 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040061, HPA046734" Approved Approved Mitochondria NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 16: Immune cells - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA040061: AB_10697713, HPA046734: AB_2732532" "unprognostic (1.85e-2)" "unprognostic (1.27e-1)" "unprognostic (7.31e-2)" "unprognostic (1.07e-1)" "unprognostic (1.11e-1)" "unprognostic (5.06e-3)" "unprognostic (1.12e-5)" "unprognostic (1.74e-1)" "unprognostic (5.12e-2)" "unprognostic (2.23e-2)" "unprognostic (2.24e-1)" "unprognostic (1.89e-1)" "unprognostic (7.72e-2)" "unprognostic (3.26e-1)" "unprognostic (4.00e-1)" "unprognostic (2.96e-2)" "unprognostic (1.05e-3)" 7.4 4.9 5.2 7.9 6.0 5.5 5.8 5.7 7.0 8.4 5.6 5.9 5.7 7.5 5.4 6.1 6.2 5.7 5.6 4.9 5.7 6.4 5.0 6.2 11.5 6.3 5.6 6.8 4.4 6.4 5.2 5.9 6.5 6.6 6.7 5.1 5.5 7.1 3.4 5.9 7.9 6.7 6.1 10.4 5.8 7.3 5.6 10.4 8.9 5.5 11.0 6.8 7.8 7.6 12.7 5.0 15.1 8.3 5.9 8.7 19.0 19.9 15.7 18.2 16.9 10.8 9.2 24.3 11.5 8.3 16.4 10.7 24.7 9.3 21.2 18.6 9.1 10.6 10.5 7.9 9.0 23.1 12.0 7.1 19.3 19.6 12.0 10.3 17.8 15.9 14.0 33.8 14.3 5.7 16.0 7.4 9.2 10.5 8.2 12.5 13.6 16.7 8.9 7.0 27.6 12.8 16.2 9.3 18.6 11.6 10.8 14.8 11.1 21.9 28.9 19.4 26.3 16.1 47.6 15.7 14.1 15.5 23.8 18.6 2.7 7.3 6.1 2.6 7.0 6.2 7.0 8.5 1.9 7.3 8.5 7.9 10.0 5.9 2.2 3.8 8.8 4.9 5.2 6.0 5.7 7.0 4.9 5.7 6.3 5.6 6.5 6.1 5.6 7.6 24.3 12.8 8.2 8.5 21.1 4.8 13.6 6.5 10.8 9.6 7.6 7.4 3.8 10.0 10.3 3.7 14.6 7.5 13.7 10.1 0.0 5.9 6.9 7.5 9.1 10.0 2.4 11.0 17.0 7.3 9.4 7.3 12.2 7.4 7.0 10.3 11.4 4.9 6.0 8.4 20.3 7.6 4.1 7.0 6.5 3.3 12.8 7.0 3.6 14.0 4.5 6.6 13.4 18.1 25.8 8.3 4.0 10.9 15.0 10.8 10.1 5.1 12.0 6.5 13.1 8.3 6.8 30.5 21.8 9.0 4.8 10.4 18.3 8.5 6.2 19.4 MGAT2 GNT-II ENSG00000168282 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase" Q10469 14 49620799-49623481 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043721, HPA056824" Approved Supported "Golgi apparatus" NA Yes 5100000 "Cluster 44: Non-specific - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA043721: AB_2678636, HPA056824: AB_2683248" "unprognostic (1.20e-2)" "prognostic unfavorable (3.22e-4)" "unprognostic (2.84e-1)" "unprognostic (5.49e-2)" "unprognostic (1.37e-1)" "unprognostic (1.70e-1)" "unprognostic (3.77e-1)" "unprognostic (1.92e-2)" "unprognostic (1.14e-1)" "unprognostic (7.44e-2)" "unprognostic (7.12e-2)" "unprognostic (5.63e-2)" "unprognostic (2.59e-3)" "unprognostic (9.14e-2)" "unprognostic (3.74e-2)" "unprognostic (4.72e-2)" "unprognostic (2.12e-2)" 16.8 17.6 5.9 24.3 5.8 10.3 13.3 6.9 6.8 17.4 9.0 23.6 23.1 12.7 21.7 11.8 11.9 15.2 11.7 5.6 6.7 14.2 40.7 13.8 25.3 6.4 6.3 13.1 23.8 8.2 7.9 22.0 6.6 14.1 21.9 8.2 15.8 13.7 5.0 9.3 22.5 16.0 6.9 20.2 21.0 24.3 7.2 16.4 13.3 5.6 25.1 20.9 8.8 7.3 63.5 30.7 23.2 39.2 53.6 51.7 15.1 68.6 67.7 62.2 55.8 37.5 47.1 63.7 56.9 62.9 36.0 49.5 32.9 39.7 66.7 65.5 29.1 40.7 21.7 37.2 42.3 94.5 91.2 39.8 31.2 36.8 51.8 45.5 75.5 31.4 31.7 170.4 66.3 24.2 32.9 60.1 23.8 22.2 49.1 36.7 67.1 55.6 49.3 36.2 24.0 25.6 49.3 12.9 39.8 22.2 39.1 63.6 78.9 56.1 60.8 41.1 49.6 182.8 94.6 56.7 27.3 46.5 38.6 49.4 38.6 39.3 36.6 34.1 39.3 25.1 33.3 33.1 39.9 15.9 19.3 26.8 11.6 22.3 39.8 47.2 31.6 44.8 5.9 5.8 6.9 6.8 5.6 6.7 6.4 6.3 6.6 6.9 7.2 7.3 17.4 12.8 8.6 2.0 31.7 15.7 25.7 28.8 14.2 13.7 15.5 8.9 0.1 24.3 18.0 11.0 4.2 26.4 46.9 34.6 9.8 31.0 7.9 12.5 20.7 20.8 12.1 19.0 3.0 34.4 40.3 24.3 13.7 11.7 17.1 27.7 27.1 63.0 37.2 18.5 4.3 20.5 40.7 34.5 28.8 6.0 17.4 26.3 21.4 2.8 40.6 16.7 63.8 6.0 4.5 36.5 25.1 22.2 77.1 27.0 26.7 15.2 23.5 15.8 6.6 15.8 34.6 56.4 13.0 15.2 14.1 5.3 31.5 23.2 20.0 25.5 MGME1 "bA504H3.4, C20orf72, DDK1" ENSG00000125871 "Mitochondrial genome maintenance exonuclease 1" Q9BQP7 20 17969018-17991122 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Disease variant, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040913 Approved Supported Mitochondria NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "HPA040913: AB_10962835" "unprognostic (5.81e-3)" "unprognostic (5.96e-2)" "unprognostic (1.28e-1)" "unprognostic (1.29e-3)" "unprognostic (5.42e-2)" "unprognostic (1.44e-2)" "prognostic unfavorable (6.98e-8)" "unprognostic (5.31e-2)" "unprognostic (7.05e-2)" "unprognostic (2.91e-2)" "unprognostic (1.06e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (1.13e-7)" "unprognostic (2.04e-1)" "unprognostic (3.22e-2)" "unprognostic (8.70e-2)" "unprognostic (6.89e-2)" 6.5 14.4 7.5 11.7 8.2 16.0 18.4 8.0 9.7 7.3 7.9 11.4 13.4 5.2 10.4 13.1 6.2 7.3 10.8 7.2 7.5 12.8 14.4 7.7 19.9 8.6 8.1 5.9 8.8 7.8 4.7 12.8 8.7 7.5 13.4 7.8 9.0 7.4 21.3 34.2 11.9 6.7 8.3 17.7 9.3 10.7 7.9 19.8 11.9 12.1 20.8 8.9 9.5 9.3 44.7 51.0 41.0 38.7 16.5 29.0 54.9 36.8 27.1 34.8 47.4 63.4 44.7 53.4 20.3 16.4 39.6 64.9 43.1 55.1 52.7 19.9 34.7 34.7 29.6 97.2 12.3 22.9 56.2 17.6 37.3 52.3 27.4 16.3 28.2 26.0 48.0 33.3 70.7 33.4 40.5 29.9 36.3 26.8 44.0 30.5 91.4 50.8 30.1 32.3 31.6 26.1 26.1 62.8 57.7 33.2 59.7 15.5 22.8 59.1 48.1 29.8 40.3 24.6 59.6 45.3 15.2 17.3 44.7 57.5 15.2 44.6 8.1 14.9 10.9 21.0 10.5 10.9 12.6 24.2 7.5 6.9 14.4 16.7 15.0 19.5 17.1 8.4 7.5 8.2 8.0 9.7 7.2 7.5 8.6 8.1 8.7 8.3 7.9 9.3 10.6 0.0 10.0 19.9 24.6 46.4 15.7 12.7 40.9 7.9 19.9 39.4 12.6 15.7 11.9 7.3 8.4 22.9 21.0 14.3 39.2 13.1 9.8 11.2 15.6 11.9 7.2 52.6 3.1 10.2 25.9 8.1 5.1 13.3 48.0 25.5 20.0 9.9 31.4 8.4 2.9 12.1 6.1 34.4 15.4 5.5 8.4 18.8 21.4 9.4 16.4 11.4 28.8 17.6 12.6 10.4 10.6 5.7 13.2 12.3 31.0 26.5 5.9 10.0 13.1 10.3 10.8 38.6 47.0 20.5 46.9 18.1 14.9 27.1 19.0 12.8 MIS18BP1 "C14orf106, FLJ11186, KIAA1903, KNL2, M18BP1" ENSG00000129534 "MIS18 binding protein 1" Q6P0N0 14 45203190-45253540 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 40.7" "Cell type enhanced" "Detected in many" "Granulosa cells: 145.1;monocytes: 150.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA006504 Approved Approved Nucleoli,Cytosol NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" Nucleoli Cytosol "HPA006504: AB_1078317" "unprognostic (2.12e-1)" "unprognostic (1.06e-1)" "unprognostic (2.58e-2)" "unprognostic (1.44e-2)" "unprognostic (1.51e-1)" "unprognostic (1.05e-2)" "prognostic unfavorable (3.83e-4)" "unprognostic (4.18e-1)" "unprognostic (1.36e-2)" "unprognostic (3.33e-1)" "unprognostic (3.32e-2)" "unprognostic (2.32e-3)" "unprognostic (3.31e-2)" "unprognostic (5.49e-2)" "unprognostic (2.30e-1)" "unprognostic (2.97e-1)" "unprognostic (2.21e-1)" 8.6 3.7 1.5 14.1 1.4 40.7 10.7 0.9 1.6 7.3 1.1 8.0 8.4 10.2 5.3 7.1 6.7 7.7 3.8 1.4 1.7 3.7 4.1 9.5 23.2 2.1 1.9 12.2 4.6 2.3 1.3 10.6 2.4 6.3 10.1 1.2 6.7 5.8 1.3 8.6 9.6 9.6 1.9 15.2 8.5 13.5 1.5 24.4 6.8 3.8 21.7 7.8 3.9 2.8 54.1 20.0 40.7 18.0 12.1 17.2 30.0 36.4 19.2 29.7 36.5 10.7 50.7 73.6 15.5 18.5 12.8 37.0 23.9 18.5 55.3 39.5 15.3 44.5 23.2 13.8 8.1 103.7 39.7 12.5 7.4 17.6 16.5 19.4 36.7 14.1 19.7 17.2 29.1 19.9 44.1 45.9 30.8 26.5 24.9 51.5 16.4 28.5 15.3 22.3 28.4 12.3 16.2 24.6 13.1 24.1 29.5 58.1 20.4 15.7 47.4 19.5 16.6 15.3 21.5 34.5 8.8 42.6 22.8 64.5 28.8 35.8 7.9 28.5 8.5 28.5 7.5 6.8 21.5 25.5 5.0 5.1 17.8 10.8 53.8 31.0 10.9 9.1 1.5 1.4 0.9 1.6 1.4 1.7 2.1 1.9 2.4 1.9 1.5 2.8 54.6 25.6 27.8 6.8 87.7 20.1 11.6 17.7 19.4 8.4 24.3 27.3 13.3 7.2 26.1 9.2 16.7 40.9 91.6 17.1 5.9 14.0 3.5 29.2 47.6 43.5 27.6 72.6 34.5 11.1 42.5 32.5 35.7 28.0 43.6 145.1 30.4 7.3 35.4 0.0 7.6 25.8 18.3 89.8 30.9 6.8 55.3 115.7 5.4 74.0 150.1 5.1 55.6 9.5 11.1 13.5 47.7 60.5 73.5 25.0 12.1 5.0 20.9 7.6 0.0 13.9 23.3 80.0 105.4 32.5 26.3 19.4 54.5 77.9 29.9 24.6 MKI67 "MIB-1, PPP1R105" ENSG00000148773 "Marker of proliferation Ki-67" P46013 10 128096659-128126423 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 46.3;lymphoid tissue: 52.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 232.9;Extravillous trophoblasts: 86.1;Granulosa cells: 87.0;Plasma cells: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB000058, HPA000451, HPA001164, CAB068198" Enhanced Enhanced "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli rim" "Mitotic chromosome" "CAB000058: AB_2142367, CAB068198: AB_2665702, HPA000451: AB_1079186, HPA001164: AB_1079187" "unprognostic (2.54e-1)" "unprognostic (1.29e-1)" "unprognostic (3.37e-1)" "unprognostic (9.92e-3)" "unprognostic (3.17e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (3.61e-6)" "unprognostic (7.16e-3)" "unprognostic (1.45e-2)" "unprognostic (3.73e-1)" "prognostic unfavorable (9.47e-5)" "unprognostic (2.45e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.42e-2)" "unprognostic (2.10e-1)" "unprognostic (2.50e-1)" "unprognostic (4.61e-1)" 0.9 0.7 0.0 8.5 0.1 46.3 1.7 0.0 0.1 1.2 0.2 8.1 6.2 1.0 0.0 10.0 0.3 0.9 0.3 0.1 0.1 0.4 0.8 1.4 14.9 0.1 1.0 0.2 0.2 0.1 0.1 4.1 0.6 0.4 9.2 0.0 1.4 0.1 0.0 6.6 5.8 2.6 0.0 4.8 4.2 2.3 0.9 52.7 0.4 0.1 16.4 1.8 2.8 0.3 204.6 101.5 103.2 73.6 4.3 8.7 32.1 75.7 55.3 70.3 62.3 83.9 82.3 152.6 21.3 51.9 46.4 120.7 109.3 56.8 104.7 161.8 53.1 131.0 79.4 52.7 0.1 186.0 68.0 2.0 2.5 72.2 73.2 17.2 69.8 69.5 61.2 142.1 70.5 80.9 111.7 56.6 41.3 52.7 45.7 82.2 135.1 20.3 25.6 56.2 35.9 38.9 107.1 38.0 17.3 33.9 31.4 39.3 65.0 37.0 73.6 53.0 206.8 64.2 54.9 177.2 30.7 83.3 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 1.0 0.6 0.0 0.9 0.3 0.6 0.0 5.4 0.0 16.0 6.4 1.6 5.3 0.6 0.0 3.9 3.2 1.6 1.5 5.3 0.0 0.0 30.6 7.4 25.0 0.0 0.8 4.2 2.3 10.2 6.7 6.7 232.9 0.0 0.0 86.1 13.5 34.7 13.2 1.3 87.0 5.7 1.7 42.1 0.0 0.0 22.4 2.0 12.9 13.7 0.9 0.3 16.6 3.6 0.0 0.2 0.0 8.2 0.0 0.0 0.1 3.0 0.4 107.4 4.6 2.6 0.1 1.6 0.0 0.0 0.5 13.6 8.1 24.1 50.4 3.0 7.8 23.0 2.7 47.1 4.8 MLF2 NTN4 ENSG00000089693 "Myeloid leukemia factor 2" Q15773 12 6747996-6767475 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010811, HPA010859" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA Yes "Cluster 5: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Plasma membrane, Cytosol" "HPA010811: AB_1079389, HPA010859: AB_1079388" "unprognostic (1.65e-1)" "unprognostic (6.55e-2)" "unprognostic (4.42e-1)" "unprognostic (9.88e-3)" "unprognostic (1.76e-1)" "unprognostic (4.19e-2)" "unprognostic (1.52e-1)" "unprognostic (4.15e-2)" "unprognostic (1.31e-1)" "unprognostic (9.11e-2)" "unprognostic (3.37e-1)" "unprognostic (6.23e-2)" "unprognostic (1.38e-1)" "unprognostic (5.83e-2)" "unprognostic (4.72e-1)" "unprognostic (8.44e-2)" "unprognostic (3.63e-1)" 121.0 199.0 214.6 67.9 225.7 123.8 109.8 206.5 243.7 119.8 215.4 161.8 106.3 148.5 85.2 168.6 120.6 68.1 181.8 234.6 219.0 163.3 298.7 107.0 66.2 208.0 205.8 116.3 111.0 158.2 145.1 79.4 205.8 142.7 74.1 78.2 131.6 96.3 192.8 144.6 117.8 93.0 205.4 101.5 135.9 97.6 211.1 78.3 114.1 129.2 71.2 135.2 117.5 223.6 222.0 354.3 179.1 294.4 159.3 157.9 283.1 216.6 230.6 318.8 286.9 353.8 195.5 163.1 55.0 265.5 228.1 173.5 220.1 295.3 220.0 274.9 239.3 115.3 174.0 200.7 176.0 128.9 143.0 151.7 240.8 255.2 209.8 257.4 140.7 152.0 152.5 61.8 247.8 320.7 165.7 197.9 554.2 236.1 141.2 102.5 160.2 134.0 310.8 247.7 111.2 224.8 188.8 303.6 203.4 385.8 89.8 186.4 133.7 191.4 279.3 213.5 299.9 80.9 98.2 208.9 259.0 102.2 231.2 259.6 120.3 461.0 82.0 109.9 80.9 85.6 63.7 78.3 134.0 97.6 66.2 75.3 528.0 76.6 129.2 231.6 69.7 115.3 214.6 225.7 206.5 243.7 234.6 219.0 208.0 205.8 205.8 205.4 211.1 223.6 106.3 38.5 30.9 19.2 77.9 136.5 149.3 230.2 261.2 110.2 157.7 156.3 71.9 92.9 108.7 110.3 41.7 264.3 92.4 120.6 279.7 169.9 12.1 64.6 70.7 86.4 100.7 74.9 36.2 125.9 213.7 100.6 91.7 74.9 84.9 84.1 71.0 168.6 147.7 80.8 32.7 138.6 197.4 57.8 70.6 13.3 114.0 78.9 103.2 13.1 138.9 142.7 39.1 19.1 23.5 153.8 124.7 107.2 108.2 202.6 219.6 324.7 58.6 63.5 52.6 77.1 131.8 96.6 80.8 193.1 125.6 427.6 70.2 138.3 145.0 174.6 MMS22L "C6orf167, dJ39B17.2" ENSG00000146263 "MMS22 like, DNA repair protein" Q6ZRQ5 6 97142161-97283217 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 67.8;Oligodendrocytes: 52.3;Spermatocytes: 56.9;Spermatogonia: 45.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA067042 Supported Nucleoplasm NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA067042: AB_2685768" "unprognostic (3.61e-2)" "unprognostic (2.80e-1)" "unprognostic (2.26e-2)" "unprognostic (1.97e-3)" "unprognostic (1.70e-1)" "unprognostic (1.52e-1)" "unprognostic (1.00e-5)" "unprognostic (9.63e-2)" "unprognostic (5.81e-3)" "unprognostic (8.21e-3)" "unprognostic (9.39e-2)" "unprognostic (6.58e-2)" "unprognostic (1.34e-6)" "unprognostic (3.48e-2)" "unprognostic (2.00e-1)" "unprognostic (1.66e-1)" "unprognostic (1.29e-1)" 1.1 1.1 0.7 2.0 1.8 7.0 2.3 1.3 1.2 1.6 0.7 1.6 1.2 1.5 0.5 1.7 1.4 1.0 0.7 0.7 1.0 0.8 0.9 1.1 3.4 2.1 1.4 1.4 1.3 1.4 0.5 2.0 1.8 1.3 2.3 2.4 1.0 0.8 0.6 2.9 1.6 1.5 1.2 1.4 1.1 6.8 1.5 5.2 1.1 0.5 3.4 1.3 1.1 2.4 7.5 8.2 13.5 14.8 2.2 4.0 10.6 15.0 6.9 13.8 20.1 11.4 8.6 16.4 9.0 5.7 16.0 13.4 17.1 8.3 27.4 14.1 12.7 16.7 11.3 7.2 1.3 25.8 11.3 2.2 4.3 19.5 9.0 2.8 6.0 15.2 23.1 25.6 13.1 8.9 9.5 10.4 5.2 12.1 6.1 15.8 12.8 5.8 5.9 9.7 7.7 6.6 9.8 4.9 4.0 7.6 7.6 15.7 4.5 14.0 13.3 11.8 20.8 3.2 10.3 18.3 8.0 16.0 15.7 0.5 0.4 0.9 0.6 0.7 1.0 0.5 0.9 1.0 1.1 0.7 0.8 1.1 0.4 0.6 1.6 1.2 0.9 0.4 0.7 1.8 1.3 1.2 0.7 1.0 2.1 1.4 1.8 1.2 1.5 2.4 5.9 3.2 8.6 16.6 9.7 9.2 5.8 4.0 4.0 11.6 6.1 6.2 4.2 5.7 6.9 3.7 41.7 12.5 14.6 3.3 1.9 2.9 67.8 4.4 6.1 6.5 1.2 26.3 11.3 4.1 11.2 6.1 7.7 2.8 7.6 24.0 10.8 3.1 6.4 3.3 7.7 8.4 8.2 7.5 6.0 17.2 9.9 6.8 7.2 36.5 6.4 6.1 6.2 22.6 52.3 3.0 2.0 5.7 13.1 2.9 5.4 0.8 6.1 31.9 6.6 7.9 5.1 56.9 45.8 7.1 8.2 3.6 9.6 5.2 10.3 3.0 MORF4L2 "KIAA0026, MRGX" ENSG00000123562 "Mortality factor 4 like 2" Q15014 X 103675496-103688158 "Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Growth regulation, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 1214.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031872, HPA054102" Supported Enhanced Nucleoplasm NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 68: Epididymis - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA031872: AB_2674081, HPA054102: AB_2682379" "prognostic unfavorable (9.83e-4)" "unprognostic (2.04e-1)" "unprognostic (1.81e-1)" "unprognostic (7.14e-3)" "unprognostic (2.59e-1)" "prognostic unfavorable (4.29e-5)" "unprognostic (5.27e-2)" "unprognostic (6.34e-3)" "unprognostic (2.41e-1)" "unprognostic (4.49e-3)" "unprognostic (1.88e-1)" "unprognostic (1.10e-2)" "prognostic unfavorable (7.86e-7)" "unprognostic (8.54e-2)" "unprognostic (2.65e-2)" "unprognostic (1.78e-1)" "unprognostic (4.05e-1)" 142.9 184.7 173.9 97.3 180.9 99.0 179.3 156.9 261.5 249.3 183.1 113.4 89.5 262.5 217.7 121.1 209.8 129.2 138.4 180.9 210.1 130.2 204.9 132.6 72.5 170.8 180.3 358.2 137.2 137.2 198.8 242.6 191.2 161.9 140.1 94.1 121.2 191.6 175.6 103.9 99.6 328.5 166.9 90.6 118.0 90.1 183.6 79.3 159.2 130.7 109.6 172.1 143.1 179.1 404.7 257.2 372.6 167.3 541.7 388.2 486.6 533.0 479.4 437.1 462.2 259.6 369.5 289.1 401.4 533.5 522.0 272.0 477.1 406.9 535.6 120.9 219.0 157.5 413.9 308.9 602.7 212.2 141.6 449.6 351.2 380.8 489.6 389.2 478.9 142.2 249.5 383.0 551.5 403.7 188.0 207.6 355.5 512.0 322.3 186.9 340.9 292.1 456.5 221.4 347.3 275.5 425.7 310.1 418.5 385.2 203.3 198.1 433.8 263.2 171.2 459.1 289.3 179.3 221.3 241.2 472.1 420.1 403.8 54.1 40.9 32.9 41.2 44.0 46.9 37.0 38.9 38.2 41.8 32.3 41.7 37.0 16.1 46.0 47.3 70.2 36.1 40.3 173.9 180.9 156.9 261.5 180.9 210.1 170.8 180.3 191.2 166.9 183.6 179.1 102.5 125.0 160.1 39.8 75.8 363.5 572.5 292.0 75.1 46.9 198.6 103.6 130.1 123.0 242.0 110.3 10.4 443.3 106.2 103.2 246.5 269.1 46.9 231.7 235.5 146.6 178.6 68.5 109.6 129.9 1214.1 266.0 90.7 187.2 155.8 153.5 118.5 196.8 163.6 58.9 104.4 202.0 219.7 61.7 254.9 34.2 330.9 90.8 188.5 32.8 68.7 117.0 40.2 59.3 78.2 176.8 118.9 574.8 120.9 332.7 105.1 282.9 429.7 38.8 144.7 164.9 287.9 37.2 48.0 112.7 317.8 583.5 118.2 171.5 134.4 396.8 MSH2 "COCA1, HNPCC, HNPCC1" ENSG00000095002 "MutS homolog 2" P43246 2 47403067-47663146 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "testis cancer: 46.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009572, HPA066845, CAB070867" Approved Supported Nucleoplasm,Vesicles NA Yes 28000 "Cluster 48: NK-cells - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Vesicles "CAB009572: AB_2144828, CAB070867: , HPA066845: AB_2732752" "unprognostic (2.35e-1)" "unprognostic (1.54e-2)" "unprognostic (2.89e-3)" "prognostic unfavorable (4.44e-4)" "unprognostic (2.23e-1)" "unprognostic (6.31e-3)" "prognostic unfavorable (1.72e-9)" "unprognostic (1.77e-1)" "unprognostic (7.09e-3)" "unprognostic (8.57e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (5.38e-2)" "unprognostic (3.29e-3)" "unprognostic (1.20e-3)" "unprognostic (5.74e-1)" "unprognostic (8.46e-2)" "unprognostic (1.48e-1)" 8.1 7.5 8.3 12.8 10.5 15.7 15.7 14.6 10.6 9.7 12.2 11.9 7.8 11.7 14.0 9.5 12.4 5.8 10.1 9.6 9.0 8.2 6.7 8.1 23.7 8.6 8.0 8.7 6.5 14.8 6.2 11.6 9.5 8.6 15.0 34.9 8.5 7.7 7.1 11.1 9.3 8.8 8.5 10.8 8.1 16.2 7.9 32.6 15.8 7.2 25.0 7.9 6.4 8.9 114.3 35.3 103.3 57.9 7.3 21.2 64.3 62.9 33.3 80.9 76.9 72.3 50.1 141.2 84.6 23.8 56.6 49.8 78.6 37.4 122.3 68.1 55.8 99.3 42.3 65.6 7.7 97.7 34.9 12.3 11.2 68.1 19.0 19.1 45.2 3.9 165.1 34.0 63.1 44.2 119.6 75.4 195.7 69.3 45.1 151.1 182.2 84.4 35.8 57.3 85.9 91.6 58.4 49.2 48.0 83.6 46.9 38.8 18.7 55.5 70.9 57.1 74.6 20.8 63.4 180.1 33.1 72.5 35.4 3.0 1.3 4.9 8.0 4.4 9.3 6.7 7.7 10.3 2.5 7.9 12.6 13.1 1.0 14.2 3.9 3.4 11.8 6.5 8.3 10.5 14.6 10.6 9.6 9.0 8.6 8.0 9.5 8.5 7.9 8.9 14.7 9.6 11.5 18.6 13.0 8.3 7.9 14.4 8.6 17.4 7.5 7.1 15.6 5.7 12.6 9.2 45.9 19.9 14.2 6.6 3.9 11.5 17.8 21.0 11.3 13.4 3.5 54.1 59.9 8.4 20.7 12.2 7.1 18.8 12.0 28.2 5.0 1.6 11.4 11.8 58.0 12.1 14.2 4.1 4.6 22.8 5.3 5.1 8.8 16.9 5.5 22.6 17.5 35.7 54.7 7.3 5.0 6.4 12.4 2.8 5.4 4.5 23.3 41.1 0.0 9.8 9.0 56.5 50.8 9.3 6.5 5.1 12.8 24.3 13.5 3.8 MSH6 GTBP ENSG00000116062 "MutS homolog 6" P52701 2 47695530-47810063 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" DNA-binding "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 119.6;Theca cells: 114.9" "Cancer enhanced" "Detected in all" "testis cancer: 31.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009091, HPA028376, HPA028446, CAB070870" Enhanced Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA Yes 15000 "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Golgi apparatus, Vesicles" "CAB009091: AB_670083, CAB070870: AB_2144959, HPA028376: AB_10598909, HPA028446: AB_10602182" "unprognostic (5.10e-2)" "unprognostic (5.87e-3)" "unprognostic (3.29e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (1.98e-1)" "unprognostic (3.09e-2)" "prognostic unfavorable (7.86e-4)" "unprognostic (1.79e-1)" "unprognostic (2.35e-3)" "unprognostic (1.01e-1)" "unprognostic (1.74e-3)" "unprognostic (8.99e-2)" "prognostic unfavorable (1.06e-7)" "unprognostic (1.22e-1)" "unprognostic (2.31e-1)" "unprognostic (9.68e-2)" "unprognostic (3.48e-2)" 11.7 22.7 9.3 17.7 13.7 24.0 16.2 15.0 12.7 15.5 12.7 13.0 9.0 27.7 10.2 11.7 17.8 10.9 9.3 8.9 11.5 12.1 19.8 11.6 28.4 12.7 11.7 53.0 31.3 17.0 9.8 20.3 13.0 15.0 12.4 21.6 10.8 15.6 10.5 13.1 9.8 27.2 10.7 12.7 10.9 35.3 11.3 36.3 17.2 11.2 31.0 12.8 12.2 19.9 116.5 77.6 128.4 37.5 42.3 46.3 67.9 63.6 51.1 60.2 59.8 67.2 41.4 158.1 84.5 59.5 82.0 46.0 130.3 74.3 82.1 80.7 69.0 117.0 60.8 71.1 28.8 131.5 37.8 38.6 28.3 60.7 41.6 53.8 40.8 5.3 115.9 69.8 61.8 85.5 144.2 80.1 130.7 81.3 37.7 219.6 204.3 84.7 44.5 76.2 92.8 100.3 79.1 40.4 42.7 124.3 54.6 42.6 33.4 72.2 92.3 54.6 80.6 63.8 79.3 276.2 61.9 77.9 42.4 7.7 3.7 3.8 4.8 6.2 5.5 4.3 5.5 5.0 5.5 4.2 8.4 4.5 2.5 5.9 6.4 2.7 5.3 3.6 9.3 13.7 15.0 12.7 8.9 11.5 12.7 11.7 13.0 10.7 11.3 19.9 19.8 28.9 21.4 5.9 19.2 25.2 22.0 12.3 31.9 25.4 14.4 15.1 8.6 2.8 21.8 7.3 35.5 35.6 20.7 7.4 3.9 15.7 46.4 27.1 31.1 18.4 4.8 47.1 8.5 9.6 21.8 24.0 8.6 31.7 17.7 119.6 13.6 10.2 13.0 15.2 12.1 9.7 20.3 5.6 13.2 17.5 25.4 16.8 3.6 7.5 10.0 22.7 8.2 9.5 27.4 9.1 3.7 22.6 31.1 16.1 2.6 6.7 22.1 31.4 6.6 27.4 33.0 54.3 48.8 22.0 17.5 9.6 19.8 114.9 12.1 11.7 MTFR2 "DUFD1, FAM54A" ENSG00000146410 "Mitochondrial fission regulator 2" Q6P444 6 136231024-136250335 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.3;lymphoid tissue: 6.4;testis: 7.0" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 23.6;Spermatocytes: 27.6;Spermatogonia: 13.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA029792, HPA029794" Approved Uncertain Vesicles NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "HPA029792: AB_10600210, HPA029794: AB_10600535" "unprognostic (6.49e-3)" "unprognostic (6.29e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (9.64e-4)" "unprognostic (3.93e-1)" "unprognostic (1.75e-2)" "unprognostic (4.60e-6)" "prognostic unfavorable (8.28e-4)" "unprognostic (3.77e-2)" "unprognostic (1.22e-1)" "unprognostic (6.27e-2)" "unprognostic (6.54e-2)" "unprognostic (1.11e-16)" "unprognostic (8.82e-3)" "unprognostic (1.55e-1)" "unprognostic (4.10e-2)" "unprognostic (3.64e-2)" 0.8 0.5 0.4 3.6 0.3 16.3 1.0 0.4 0.6 0.6 0.2 2.9 2.8 0.5 0.3 2.6 0.3 0.3 0.3 0.4 0.3 0.6 0.4 1.2 6.4 0.4 0.5 0.3 0.4 0.0 0.4 1.8 0.3 0.4 3.8 0.5 0.8 0.2 1.2 1.9 2.3 1.1 0.4 2.2 1.2 7.0 0.4 6.2 0.3 0.1 5.3 0.8 0.9 0.4 15.2 11.5 9.7 18.2 1.6 2.8 17.4 19.6 13.6 22.8 31.7 20.7 12.2 39.2 11.7 7.9 30.1 23.1 22.3 14.4 33.8 22.1 17.1 31.0 7.8 18.9 1.0 57.4 28.1 2.3 3.1 25.5 16.1 2.7 12.4 33.8 33.9 29.6 17.2 20.2 32.5 47.8 9.8 20.2 14.1 29.3 15.5 19.7 9.9 11.6 7.7 7.6 12.4 21.5 11.3 11.9 9.1 39.1 6.8 11.3 11.8 40.2 30.4 11.2 28.3 26.1 6.5 38.5 17.6 0.0 0.2 0.0 0.3 0.9 0.1 0.4 0.4 0.7 0.9 0.3 0.0 0.4 0.0 0.0 0.7 0.7 0.7 0.3 0.4 0.3 0.4 0.6 0.4 0.3 0.4 0.5 0.3 0.4 0.4 0.4 2.0 0.0 1.1 0.0 2.2 1.0 0.6 3.1 0.0 0.0 3.4 3.6 0.4 0.0 2.3 0.0 0.0 8.4 1.3 2.2 0.0 1.1 7.9 2.4 1.3 1.7 0.0 9.9 0.5 2.5 23.6 1.5 2.6 2.5 1.3 3.5 0.7 0.5 6.6 0.0 0.4 2.1 4.1 3.8 2.1 5.9 0.3 2.5 0.0 1.0 2.3 0.0 1.0 0.5 0.0 1.3 0.4 0.0 7.4 1.2 1.3 1.4 2.5 0.0 0.0 5.3 1.8 27.6 13.0 5.3 0.3 3.0 3.1 0.8 4.6 0.9 MTHFD1 "MTHFC, MTHFD" ENSG00000100714 "Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1" 14 64388031-64463457 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 356.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 142.9;Proximal tubular cells: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000704, HPA001290, HPA015006, HPA050052" Approved Enhanced Cytosol NA Yes "Cluster 43: B-cells - Humoral immune response" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA000704: AB_1079424, HPA001290: AB_1854177, HPA015006: AB_1854178, HPA050052: AB_2680998" "unprognostic (3.58e-2)" "unprognostic (5.50e-3)" "unprognostic (1.24e-1)" "unprognostic (2.46e-2)" "unprognostic (1.37e-1)" "unprognostic (7.01e-2)" "unprognostic (8.85e-3)" "unprognostic (7.62e-3)" "unprognostic (1.28e-1)" "unprognostic (2.29e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (1.84e-1)" "prognostic favorable (5.93e-5)" "unprognostic (2.45e-2)" "unprognostic (1.75e-1)" "unprognostic (7.30e-2)" "unprognostic (2.29e-2)" 56.4 18.0 8.6 20.0 17.4 27.0 29.8 8.3 12.3 16.9 15.0 23.3 19.7 16.1 9.9 25.1 16.0 13.1 28.1 12.9 8.1 55.3 356.9 15.4 23.6 7.5 7.8 24.9 23.8 27.5 9.2 13.3 7.0 12.9 27.5 3.6 15.6 13.8 64.1 17.1 18.9 20.0 7.2 14.5 17.9 4.7 8.9 30.2 20.5 61.9 27.7 18.6 16.6 8.3 294.1 164.9 58.5 143.6 70.5 53.4 95.7 106.4 83.3 148.1 147.4 161.2 144.2 103.3 49.6 67.1 68.3 146.0 177.6 111.2 160.4 107.3 117.9 122.2 143.5 131.8 50.6 104.5 81.2 43.0 37.3 124.3 66.4 57.5 93.1 98.1 108.5 98.7 114.7 270.1 179.9 62.3 118.0 186.5 160.4 138.3 201.2 114.4 110.5 160.9 128.7 49.0 183.7 111.4 58.3 54.0 164.4 58.6 51.5 115.1 184.1 102.2 134.2 58.8 65.6 177.9 107.4 125.2 134.8 0.4 11.7 0.1 9.7 19.5 13.0 27.0 10.1 12.3 17.7 15.3 7.8 10.7 0.9 17.8 16.7 4.0 19.5 12.2 8.6 17.4 8.3 12.3 12.9 8.1 7.5 7.8 7.0 7.2 8.9 8.3 8.1 19.2 23.5 15.0 16.2 13.8 14.2 14.7 13.6 0.0 9.8 8.1 43.9 15.7 19.5 16.5 0.0 30.6 10.8 7.9 41.1 16.9 1.4 6.8 11.7 12.3 3.0 42.3 19.5 10.3 30.9 14.9 15.3 8.7 50.7 27.2 12.8 142.9 25.3 0.0 15.6 14.3 2.0 13.0 11.0 1.5 13.1 12.3 14.2 8.4 13.3 0.0 8.2 14.1 10.9 11.7 6.3 13.2 24.1 10.2 8.2 75.3 11.5 0.0 19.7 13.1 19.3 0.9 8.9 19.5 10.7 9.9 16.6 21.4 24.6 12.7 MXD3 "bHLHc13, MAD3" ENSG00000213347 "MAX dimerization protein 3" Q9BW11 5 177301461-177312757 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 45.7;Granulosa cells: 24.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.7" "Group enriched" "Detected in many" 5 "B-cells: 4.1;granulocytes: 16.7;monocytes: 10.9" "Cell line enhanced" "Detected in many" "HDLM-2: 176.0" "Group enriched" "Detected in many" 5 "amygdala: 1.8;basal ganglia: 2.0;cerebral cortex: 1.1;hippocampal formation: 1.0;white matter: 2.4" "Low region specificity" "Detected in all" HPA070111 Approved Nucleoplasm,Nucleoli NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli" "HPA070111: AB_2686228" "unprognostic (2.78e-1)" "unprognostic (1.32e-2)" "unprognostic (2.11e-1)" "unprognostic (3.63e-1)" "unprognostic (8.26e-2)" "unprognostic (6.18e-3)" "prognostic unfavorable (3.60e-4)" "unprognostic (3.32e-1)" "unprognostic (6.84e-2)" "unprognostic (3.12e-2)" "unprognostic (4.97e-2)" "unprognostic (2.84e-2)" "unprognostic (3.33e-16)" "unprognostic (8.55e-3)" "unprognostic (2.22e-1)" "unprognostic (1.61e-1)" "unprognostic (3.22e-3)" 5.8 5.1 1.9 6.5 2.1 39.3 6.1 1.6 4.6 7.1 2.0 9.4 7.1 5.6 1.4 13.2 7.9 1.0 4.8 1.7 2.0 6.3 14.2 8.3 7.8 2.7 2.0 5.5 12.1 0.4 8.5 1.9 2.6 9.9 0.8 0.4 6.7 1.8 4.0 10.8 10.8 1.2 1.6 19.0 8.1 6.8 2.7 10.5 7.1 0.4 2.4 6.8 7.8 4.0 24.2 16.8 9.9 27.3 0.6 1.3 16.8 31.2 10.0 13.6 13.0 11.9 24.6 12.9 12.6 4.2 7.8 12.1 1.1 3.6 0.7 176.0 22.1 7.7 25.5 16.3 1.4 7.5 21.3 1.1 1.8 0.9 0.6 1.2 12.7 55.1 4.6 39.0 2.8 31.2 64.9 19.7 3.7 7.8 28.2 31.5 30.9 18.7 3.1 3.7 24.3 20.3 19.9 19.9 11.1 1.6 31.3 18.4 9.5 16.5 41.6 13.1 17.0 51.1 18.6 14.8 12.9 24.3 9.7 4.1 3.1 9.9 0.7 9.1 0.0 1.8 0.2 0.1 2.1 4.1 0.1 0.4 16.7 1.0 10.9 1.3 0.9 1.7 1.9 2.1 1.6 4.6 1.7 2.0 2.7 2.0 2.6 1.6 2.7 4.0 1.9 3.2 3.6 5.2 4.9 5.6 2.5 4.9 0.6 2.6 7.0 5.1 2.2 2.8 4.6 5.5 0.0 16.7 4.8 8.9 0.0 1.3 15.5 3.8 3.7 4.1 1.8 45.7 3.4 3.9 6.6 6.0 8.6 3.4 9.5 24.5 4.6 4.3 10.3 3.3 3.0 10.9 4.1 6.0 5.0 2.2 1.8 6.5 3.6 1.9 5.2 1.7 2.1 2.0 3.6 2.3 3.4 1.5 18.5 3.9 4.4 0.8 6.6 2.3 0.0 2.1 4.4 1.0 6.2 10.2 5.7 13.1 5.6 1.9 12.5 3.4 MYBL2 "B-MYB, BMYB" ENSG00000101057 "MYB proto-oncogene like 2" P10244 20 43667019-43716495 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 91.8;lymphoid tissue: 55.5" "Cell type enhanced" "Detected in many" "B-cells: 33.0;dendritic cells: 32.6;Erythroid cells: 82.3;Extravillous trophoblasts: 32.3;Plasma cells: 139.6;Spermatogonia: 33.6" "Cancer enriched" "Detected in all" 5 "testis cancer: 295.8" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 34 "plasmacytoid DC: 91.5" "Lineage enriched" "Detected in many" 34 "dendritic cells: 91.5" "Cell line enhanced" "Detected in many" "MCF7: 763.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017114, HPA030530, HPA055416" Uncertain Supported Nucleoplasm,Cytosol Yes Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm Cytosol "CAB017114: , HPA030530: AB_2673515, HPA055416: AB_2682811" "unprognostic (9.75e-3)" "unprognostic (1.29e-2)" "unprognostic (3.20e-1)" "prognostic unfavorable (9.73e-4)" "unprognostic (2.35e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (2.11e-7)" "unprognostic (2.66e-3)" "unprognostic (9.23e-3)" "unprognostic (1.78e-1)" "unprognostic (2.38e-3)" "unprognostic (1.32e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.42e-1)" "unprognostic (2.27e-1)" "unprognostic (1.19e-1)" "unprognostic (1.84e-1)" 1.6 0.6 0.1 24.2 0.1 91.8 1.6 0.1 0.2 1.1 0.2 8.6 7.0 1.4 0.1 10.1 0.4 1.0 0.4 0.1 0.1 0.6 1.1 1.8 55.5 0.1 0.1 0.3 11.2 0.1 0.2 5.7 0.1 0.5 6.9 0.0 1.6 0.2 0.1 4.2 7.8 2.1 0.1 27.8 6.1 15.6 0.4 33.3 0.5 0.0 53.5 3.5 2.5 0.1 195.8 121.8 105.4 109.6 1.0 3.5 136.2 87.0 29.0 265.6 194.6 600.2 118.8 393.6 49.2 37.8 55.8 116.1 192.1 59.6 98.8 74.2 124.1 183.2 118.7 164.2 0.2 168.6 121.7 2.4 5.1 101.6 22.9 5.9 72.2 189.6 188.1 470.3 23.8 763.7 346.0 236.3 121.8 155.4 105.4 237.3 216.3 222.1 49.6 39.7 96.7 140.6 255.6 253.3 26.1 110.4 167.2 183.1 34.0 16.3 264.3 118.3 151.5 162.1 363.8 606.5 34.2 142.3 103.9 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.3 0.0 1.4 0.0 0.0 0.1 0.2 0.0 91.5 1.3 0.8 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.2 0.0 0.0 0.0 33.0 4.2 0.8 0.8 0.0 0.0 2.5 3.4 2.0 1.5 0.1 0.0 0.0 14.4 32.6 3.4 0.0 0.4 5.9 0.9 1.3 1.8 0.0 82.3 0.4 0.9 32.3 4.8 10.2 2.9 0.0 18.9 0.7 1.4 13.5 0.0 0.3 5.1 0.0 2.4 2.6 14.1 0.0 3.2 1.8 0.0 0.0 0.0 1.0 0.0 0.5 0.7 1.1 0.0 139.6 0.3 0.5 0.0 0.0 0.0 0.0 0.1 3.9 7.0 33.6 8.2 2.4 3.7 3.0 1.2 8.6 2.4 MYL12A "MLCB, MRCL3, MRLC3, MYL2B" ENSG00000101608 "Myosin light chain 12A" P19105 18 3247481-3256236 "Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 4234.5;skeletal muscle: 3072.7;tongue: 2082.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 6094.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004503, HPA039262, HPA045244, HPA059197" Supported NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 38: Heart - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB004503: AB_2282358, HPA039262: AB_2676418, HPA045244: AB_2679269, HPA059197: AB_2683944" "unprognostic (2.14e-3)" "unprognostic (5.30e-2)" "unprognostic (1.80e-1)" "unprognostic (5.31e-2)" "unprognostic (3.03e-2)" "unprognostic (7.95e-2)" "unprognostic (1.41e-1)" "unprognostic (1.57e-3)" "unprognostic (2.02e-1)" "unprognostic (2.53e-2)" "unprognostic (1.49e-3)" "unprognostic (2.30e-1)" "unprognostic (9.86e-2)" "unprognostic (1.30e-1)" "unprognostic (4.98e-2)" "unprognostic (4.58e-3)" "unprognostic (7.13e-2)" 492.0 246.2 83.6 358.2 86.6 455.0 423.8 91.2 123.7 311.2 114.1 448.8 315.2 258.1 267.0 410.9 274.7 354.6 4234.5 81.0 97.2 427.9 462.3 564.8 562.8 101.2 89.5 191.4 228.8 364.4 106.9 445.4 101.7 247.4 486.6 50.7 282.4 245.6 3072.7 280.7 332.6 317.3 97.0 566.3 369.0 106.8 93.5 461.6 314.3 2082.4 601.6 408.3 240.5 96.8 467.6 298.1 580.7 257.3 701.6 691.8 386.7 1045.3 1176.5 827.9 895.4 440.7 543.5 224.6 263.9 1412.9 627.3 192.7 360.9 601.0 736.0 326.9 129.4 236.6 297.2 360.0 1118.3 658.7 401.0 1129.5 803.3 698.0 420.0 799.7 1332.7 272.6 292.6 694.7 1748.4 793.6 282.9 571.7 253.3 496.5 199.3 167.0 341.1 384.7 1827.8 680.1 86.7 211.5 840.9 333.1 674.0 541.8 233.8 918.2 1717.0 212.6 508.4 635.5 828.0 166.9 278.8 351.6 665.5 249.5 798.1 3164.3 1120.8 2382.2 2287.2 1192.8 2280.2 1588.6 2106.9 2315.1 1639.0 1353.6 1901.6 2215.8 1785.1 1629.3 1464.6 2487.8 2068.3 4517.7 83.6 86.6 91.2 123.7 81.0 97.2 101.2 89.5 101.7 97.0 93.5 96.8 1206.6 737.2 291.0 4.6 530.9 635.9 973.5 1804.3 259.6 29.4 294.8 396.4 6094.3 449.0 949.8 511.3 12.5 748.1 1090.0 1033.5 471.6 1335.5 32.4 570.0 312.1 938.8 105.4 244.9 1.7 1487.7 1168.6 453.0 318.5 662.3 521.0 301.7 870.6 272.5 844.2 57.2 2.9 570.4 889.0 605.3 992.8 32.8 334.6 924.2 442.9 26.2 1616.2 92.6 1388.3 4.0 9.0 2236.5 977.2 396.5 207.4 817.8 758.0 757.7 673.1 42.4 571.9 378.7 757.0 78.9 166.5 262.6 545.1 666.0 1078.8 303.7 429.6 698.2 MYO19 "FLJ22865, MYOHD1" ENSG00000278259 "Myosin XIX" Q96H55 17 36495636-36543435 "Predicted intracellular proteins" "Actin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 81.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021415, HPA059715" Approved Enhanced Mitochondria,Cytosol NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Mitochondria Cytosol "HPA021415: AB_2266815, HPA059715: AB_2684111" "unprognostic (3.12e-1)" "unprognostic (2.38e-1)" "unprognostic (8.44e-3)" "unprognostic (1.46e-1)" "unprognostic (2.02e-1)" "unprognostic (4.89e-3)" "prognostic unfavorable (8.33e-6)" "unprognostic (1.07e-3)" "unprognostic (1.39e-2)" "unprognostic (2.41e-1)" "unprognostic (1.67e-1)" "unprognostic (3.70e-3)" "unprognostic (1.47e-2)" "unprognostic (1.50e-2)" "unprognostic (1.57e-1)" "unprognostic (1.89e-1)" "unprognostic (4.17e-2)" 7.8 5.5 2.3 7.1 2.6 13.1 8.0 2.3 3.0 11.3 3.5 11.7 13.0 7.3 5.2 22.1 7.5 4.9 5.6 2.3 2.4 13.5 11.1 7.8 5.7 3.0 2.4 6.8 13.2 17.0 9.5 6.4 3.2 7.9 14.6 2.1 15.4 3.9 8.5 24.2 13.0 7.2 2.2 8.4 14.4 9.6 2.9 6.4 9.4 4.5 10.0 7.3 14.5 3.1 41.6 47.3 21.7 25.1 10.1 12.5 32.5 34.0 27.0 53.2 57.9 42.6 46.4 21.9 15.6 23.3 20.0 66.5 48.0 38.3 36.8 18.9 24.0 30.6 58.8 29.4 8.4 36.5 40.0 6.9 20.2 41.6 40.8 13.5 22.2 29.7 46.5 24.2 28.2 28.9 25.3 29.4 23.9 44.1 20.4 32.8 30.7 28.4 27.7 32.3 37.9 18.5 44.9 31.7 15.4 30.3 55.2 17.6 15.9 32.8 41.1 47.5 65.3 19.8 41.4 21.3 22.8 24.7 44.5 0.5 0.6 0.4 1.1 0.4 0.9 0.6 0.7 1.1 1.2 0.5 0.6 1.2 0.0 1.4 0.2 0.6 0.6 0.4 2.3 2.6 2.3 3.0 2.3 2.4 3.0 2.4 3.2 2.2 2.9 3.1 13.1 9.6 12.0 23.8 12.3 29.6 12.3 14.4 23.9 18.4 11.0 12.3 4.4 17.2 8.6 5.5 35.5 12.0 9.6 24.4 1.9 10.7 81.4 10.6 12.7 10.6 10.8 24.6 25.8 13.3 21.6 9.6 23.9 16.7 2.5 20.4 6.8 9.5 10.9 3.3 36.4 23.5 14.2 7.9 10.1 20.8 12.5 7.8 3.6 10.3 11.0 3.9 15.5 22.6 24.4 16.4 13.9 9.8 19.4 26.4 23.0 4.4 6.4 24.8 0.0 13.3 9.0 19.7 19.4 29.1 23.4 7.3 13.0 9.9 32.5 16.3 MZT1 "C13orf37, FLJ21869, LOC440145, MGC150539, MOZART1, RP11-11C5.2" ENSG00000204899 "Mitotic spindle organizing protein 1" Q08AG7 13 72708367-72727629 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 122.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063299, HPA066715" Approved NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 32: U-937 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" "HPA063299: AB_2684980, HPA066715: AB_2685709" "unprognostic (1.52e-1)" "unprognostic (3.38e-2)" "unprognostic (1.48e-1)" "unprognostic (4.89e-1)" "unprognostic (2.46e-1)" "unprognostic (2.38e-3)" "prognostic unfavorable (3.22e-5)" "unprognostic (2.65e-2)" "unprognostic (6.88e-2)" "unprognostic (5.28e-2)" "unprognostic (7.09e-2)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.01e-5)" "unprognostic (9.01e-3)" "unprognostic (5.23e-1)" "unprognostic (1.60e-1)" "unprognostic (1.26e-1)" 9.0 15.1 11.8 11.6 15.5 26.3 11.6 12.6 18.4 8.6 10.2 8.8 8.3 8.3 9.1 9.8 6.1 6.1 12.0 12.3 12.7 11.1 5.5 8.1 17.2 10.4 11.3 7.3 5.8 8.2 6.7 10.6 10.1 10.3 10.0 9.9 9.5 6.3 19.2 9.6 7.4 7.2 11.3 9.8 9.2 6.4 13.1 17.5 12.1 15.0 13.1 9.3 6.1 10.8 97.5 15.4 53.1 39.4 10.8 18.0 43.5 77.1 31.9 47.7 54.8 28.9 62.3 66.9 57.5 30.9 30.1 30.8 53.6 28.7 86.1 80.6 54.5 86.9 30.0 44.0 15.0 147.1 68.1 9.8 28.8 28.9 59.4 28.8 49.1 76.7 48.7 51.1 95.1 17.5 75.2 81.9 40.5 58.7 28.7 52.6 60.7 33.2 42.9 23.8 62.3 56.9 32.7 47.8 48.4 29.0 36.1 72.1 33.5 41.9 47.7 59.5 94.8 46.5 77.0 53.1 98.2 88.8 87.6 16.2 3.8 8.5 4.8 6.9 6.0 7.7 6.5 6.0 4.8 7.3 8.3 6.7 2.0 7.2 7.6 6.3 9.9 3.8 11.8 15.5 12.6 18.4 12.3 12.7 10.4 11.3 10.1 11.3 13.1 10.8 29.3 0.0 15.2 5.5 49.9 55.1 27.6 32.2 30.7 29.3 32.8 24.5 17.8 12.8 18.7 31.3 14.6 57.3 38.3 10.3 58.7 25.9 4.5 20.5 18.0 26.5 21.7 122.3 15.2 24.4 98.8 23.1 18.3 18.8 18.4 27.0 20.7 8.8 41.3 63.9 17.1 17.6 38.7 32.3 46.4 4.2 19.9 33.1 60.5 3.7 36.0 31.1 23.7 6.0 10.0 25.1 15.2 16.6 47.9 33.7 8.1 46.5 12.9 27.7 32.9 21.4 26.8 52.0 38.2 51.9 57.4 30.2 43.8 17.6 24.2 32.3 NACA NACA1 ENSG00000196531 "Nascent polypeptide associated complex subunit alpha" "E9PAV3, Q13765" 12 56712305-56731628 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport" "Activator, Chaperone, DNA-binding" Allergen "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA073152, HPA073648" Approved Cytosol NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Cytosol "HPA073152: AB_2686575, HPA073648: AB_2686621" "unprognostic (3.35e-2)" "unprognostic (9.98e-3)" "unprognostic (1.56e-1)" "unprognostic (2.30e-3)" "unprognostic (4.03e-2)" "unprognostic (2.81e-1)" "unprognostic (1.24e-3)" "unprognostic (1.55e-1)" "unprognostic (3.92e-2)" "unprognostic (2.95e-2)" "unprognostic (5.64e-2)" "unprognostic (8.45e-2)" "prognostic unfavorable (4.58e-11)" "unprognostic (9.47e-2)" "unprognostic (6.28e-2)" "unprognostic (7.00e-2)" "unprognostic (9.79e-2)" 1348.3 1065.0 446.1 607.2 455.9 1524.0 1460.8 456.4 614.8 1642.2 421.9 1252.3 618.6 1067.1 1084.0 1511.9 1216.9 545.1 946.9 431.4 473.1 1038.4 893.7 839.1 1026.5 465.7 442.5 2391.0 1384.8 764.5 811.6 607.7 469.4 1139.7 845.2 453.0 1016.0 699.0 1192.4 1706.1 890.4 689.9 492.3 901.9 1035.1 364.0 450.6 1043.6 918.0 376.8 1432.0 1183.1 1447.1 485.1 1128.5 1333.7 1555.7 1198.7 1795.5 3053.1 1489.5 1117.9 1619.4 1509.9 1051.6 1602.0 1220.7 2014.8 1191.0 1019.4 599.8 963.6 1324.0 1814.9 1600.2 1002.6 2111.7 1463.4 890.3 1640.8 1607.2 2139.1 899.1 2430.3 2204.4 1226.9 2477.6 2669.6 1628.2 1184.8 1896.0 2594.7 1445.5 1118.9 1341.7 2670.1 1528.3 1072.6 1440.8 1543.1 1268.7 2180.1 2124.9 1157.6 1130.2 1197.4 835.8 1977.1 1774.5 1027.8 2109.8 2398.2 1085.4 770.4 933.2 834.0 1127.0 1217.9 1475.1 1768.0 1134.0 1422.3 997.9 462.6 987.0 503.8 581.4 1371.7 851.7 969.7 823.0 726.5 1006.8 812.1 941.6 834.7 350.2 748.7 1842.6 1082.7 944.3 1951.8 446.1 455.9 456.4 614.8 431.4 473.1 465.7 442.5 469.4 492.3 450.6 485.1 1444.2 445.5 645.8 38.8 1822.8 2027.4 2219.5 2022.2 2405.1 325.2 2494.6 5365.8 722.7 1159.6 1095.8 395.4 66.7 1867.2 2037.7 656.8 1778.5 1368.9 701.0 899.4 1625.1 1206.0 647.6 1213.0 31.4 2023.3 2894.2 1085.3 649.4 1079.9 735.9 1600.7 993.4 881.6 1594.4 183.4 35.5 1461.3 801.5 1436.7 1664.7 589.5 2409.8 1430.9 1239.8 40.3 2261.1 1195.0 1528.3 26.7 35.1 1574.8 1306.2 1431.2 1160.8 2248.0 1444.7 2734.4 523.2 455.2 802.0 1977.5 1718.3 542.4 479.1 2363.5 2231.6 2323.4 1549.8 2175.1 1762.0 2618.2 NASP "DKFZp547F162, FLB7527, FLJ31599, FLJ35510, MGC19722, MGC20372, MGC2297, PRO1999" ENSG00000132780 "Nuclear autoantigenic sperm protein" P49321 1 45583846-45618904 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 476.2;Spermatogonia: 514.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028136, HPA030518, HPA030520" Enhanced Enhanced Nucleoplasm NA Yes 170000 "Cluster 24: B-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 5: NTERA-2 - Transcription" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA028136: AB_2672497, HPA030518: AB_2673509, HPA030520: AB_2673510" "unprognostic (5.59e-2)" "unprognostic (1.34e-3)" "unprognostic (5.02e-1)" "unprognostic (2.24e-1)" "unprognostic (1.23e-1)" "unprognostic (5.36e-3)" "prognostic unfavorable (4.96e-6)" "unprognostic (2.59e-1)" "prognostic unfavorable (3.67e-4)" "unprognostic (1.56e-2)" "unprognostic (1.15e-1)" "unprognostic (1.78e-2)" "prognostic unfavorable (1.91e-8)" "unprognostic (1.62e-2)" "unprognostic (4.83e-2)" "unprognostic (7.73e-2)" "unprognostic (5.32e-2)" 66.2 39.6 57.4 55.9 62.6 165.0 58.8 60.6 95.7 67.4 57.1 52.7 34.6 54.6 29.9 55.2 65.6 26.7 51.0 57.2 68.0 48.6 52.0 50.4 91.5 65.0 61.6 72.4 34.9 41.1 40.9 61.9 63.0 54.1 51.5 38.2 43.5 43.4 41.7 46.7 58.3 45.1 56.0 83.3 47.3 108.9 62.4 100.7 48.1 22.2 97.7 51.1 56.0 65.3 191.3 110.8 520.2 184.6 85.8 44.9 243.8 150.9 112.4 230.5 286.5 205.7 134.4 357.9 103.5 65.8 251.9 180.2 351.9 161.0 291.5 164.0 222.9 462.7 201.6 326.9 30.2 489.3 186.4 52.5 38.3 254.0 87.6 60.1 159.5 294.8 396.3 204.1 157.6 131.4 559.6 445.0 755.5 189.5 93.1 697.4 454.0 343.8 115.3 189.4 198.3 239.8 248.7 140.4 159.7 389.2 100.8 377.0 86.7 105.5 322.8 204.4 250.0 124.5 251.2 616.2 107.6 306.7 107.3 6.4 9.4 10.9 14.1 12.1 16.4 16.1 16.1 16.3 14.3 22.3 13.9 13.7 4.0 9.7 7.3 14.7 22.0 9.1 57.4 62.6 60.6 95.7 57.2 68.0 65.0 61.6 63.0 56.0 62.4 65.3 196.5 57.7 106.7 70.8 136.1 78.1 135.2 72.4 133.7 45.3 77.4 87.4 58.4 37.1 99.1 36.8 37.5 319.3 150.8 64.8 31.3 55.0 16.6 119.6 138.1 138.4 51.3 142.8 32.7 37.4 223.2 100.6 81.1 137.9 115.2 134.2 90.3 38.6 108.1 43.7 34.8 68.1 44.7 43.7 62.6 26.6 94.8 82.7 40.9 31.9 52.3 60.9 62.8 63.8 160.3 29.8 44.9 78.2 107.4 88.6 28.9 36.6 109.1 77.3 85.5 148.1 106.6 476.2 514.5 92.1 57.0 268.2 142.2 90.7 101.7 85.3 NCAPD2 "CAP-D2, CNAP1, hCAP-D2, KIAA0159" ENSG00000010292 "Non-SMC condensin I complex subunit D2" Q15021 12 6493356-6531955 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 76.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 48.0;Late spermatids: 34.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012423, HPA036947, HPA037363" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA Yes 34000 "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Nucleoplasm, Nucleoli" "CAB012423: , HPA036947: AB_10671367, HPA037363: AB_10672483" "unprognostic (1.51e-1)" "unprognostic (1.88e-1)" "unprognostic (2.20e-1)" "unprognostic (1.31e-2)" "unprognostic (1.03e-2)" "unprognostic (7.84e-2)" "prognostic unfavorable (1.79e-8)" "unprognostic (2.73e-3)" "unprognostic (1.45e-2)" "unprognostic (5.00e-2)" "unprognostic (5.41e-3)" "unprognostic (4.53e-1)" "prognostic unfavorable (1.13e-7)" "unprognostic (4.80e-3)" "unprognostic (1.18e-1)" "unprognostic (4.53e-1)" "unprognostic (8.75e-2)" 8.3 7.4 7.3 21.5 11.4 35.5 10.9 9.9 8.3 10.2 7.4 17.9 17.0 10.7 10.6 15.9 11.2 9.8 7.6 7.2 8.0 7.4 4.8 10.6 38.1 11.0 10.0 8.0 7.7 11.3 5.5 17.5 11.7 9.4 20.4 11.1 11.8 10.2 7.9 21.9 16.0 13.4 8.4 16.1 12.1 18.2 10.2 76.8 11.3 10.2 44.8 10.1 9.3 13.9 125.3 99.3 134.6 97.9 29.9 28.4 159.2 76.1 69.8 138.3 109.1 123.5 150.8 135.8 24.2 63.2 126.7 128.6 188.0 105.4 194.1 214.1 92.8 112.2 113.8 79.4 12.5 145.0 96.5 20.5 31.6 112.4 107.8 61.9 89.9 94.0 71.0 63.4 104.7 79.6 162.2 73.8 207.5 129.9 78.2 153.7 260.6 77.7 39.5 64.1 54.0 61.9 121.5 64.9 44.3 189.1 27.0 101.7 51.0 94.1 149.6 60.8 168.4 45.3 51.7 181.0 55.7 92.2 126.1 11.0 1.7 3.7 7.1 2.8 5.3 5.1 6.4 7.3 3.4 3.5 7.3 7.3 1.4 8.1 2.2 4.1 8.3 3.9 7.3 11.4 9.9 8.3 7.2 8.0 11.0 10.0 11.7 8.4 10.2 13.9 4.3 6.4 7.4 4.9 11.0 3.6 3.8 4.4 17.1 3.7 4.7 6.9 4.1 5.7 3.4 1.8 8.4 13.5 8.9 7.3 0.0 4.5 18.3 5.3 6.3 5.4 1.2 48.0 5.6 3.7 17.8 6.4 7.1 5.8 3.8 20.0 8.9 3.3 10.1 5.0 5.0 9.9 6.1 16.4 4.4 34.3 5.9 10.8 0.0 2.8 9.5 11.8 15.5 2.5 17.8 5.3 4.6 6.0 22.6 4.1 6.0 2.4 4.2 8.4 0.0 4.2 5.2 21.3 13.7 19.3 3.4 6.3 12.0 6.1 14.7 4.1 NCAPG "CAP-G, FLJ12450, hCAP-G, YCG1" ENSG00000109805 "Non-SMC condensin I complex subunit G" Q9BPX3 4 17810979-17844865 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.9;lymphoid tissue: 15.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 59.3;Extravillous trophoblasts: 26.6;Plasma cells: 20.4;Spermatocytes: 63.7;Spermatogonia: 24.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in single" "white matter: 1.6" "Low region specificity" "Detected in all" HPA039613 Uncertain NA Yes 9500 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA039613: AB_10805481" "unprognostic (5.23e-2)" "unprognostic (3.37e-1)" "unprognostic (1.59e-3)" "prognostic unfavorable (8.28e-4)" "unprognostic (4.22e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (3.13e-6)" "unprognostic (1.18e-3)" "unprognostic (1.63e-2)" "unprognostic (6.70e-2)" "prognostic unfavorable (7.65e-5)" "unprognostic (3.44e-2)" "unprognostic (0.00e+0)" "unprognostic (1.94e-2)" "unprognostic (1.34e-1)" "unprognostic (1.67e-1)" "unprognostic (2.07e-1)" 0.7 0.5 0.1 4.1 0.1 13.9 0.9 0.5 0.1 0.7 0.2 3.0 3.8 0.6 0.0 3.5 0.2 0.9 0.3 0.0 0.2 0.2 0.7 0.6 8.7 0.6 1.2 0.2 0.2 0.1 0.1 3.0 0.7 0.3 2.4 0.3 0.7 0.0 0.2 3.5 3.2 1.0 1.2 2.1 1.9 5.6 0.3 15.8 0.3 0.1 8.7 1.2 1.0 0.2 45.1 28.3 63.8 42.2 4.0 7.8 23.1 56.8 22.2 55.0 55.8 36.3 26.8 66.8 11.3 16.0 47.6 19.9 54.5 22.1 74.8 30.5 27.0 53.6 37.3 29.8 0.2 38.4 20.3 1.5 1.5 40.7 18.6 8.8 27.9 28.9 53.1 74.1 55.0 13.4 44.1 36.9 32.8 26.1 27.9 42.8 57.4 28.0 16.6 13.9 50.0 29.7 51.2 10.9 15.7 27.2 25.6 21.3 23.2 52.5 23.6 30.0 78.9 23.2 23.3 56.1 21.7 39.1 35.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.6 0.4 0.1 0.1 0.5 0.1 0.0 0.2 0.6 1.2 0.7 1.2 0.3 0.2 0.3 0.0 1.1 0.0 3.3 2.4 0.6 1.9 1.2 0.2 0.6 0.6 0.2 0.0 0.8 0.0 0.0 11.7 1.6 2.9 0.0 0.1 15.8 0.9 1.9 1.7 1.8 59.3 0.2 0.0 26.6 3.8 7.1 2.3 1.3 14.2 2.2 0.5 9.5 0.0 0.4 3.1 2.0 2.6 2.9 9.5 0.6 3.7 1.8 1.0 0.7 0.3 3.1 0.5 0.5 0.2 0.1 0.0 20.4 0.4 0.2 0.0 0.0 0.2 0.0 0.2 4.3 63.7 24.3 11.0 1.1 2.2 3.7 0.7 5.6 1.3 NCAPH "BRRN1, CAP-H, hCAP-H" ENSG00000121152 "Non-SMC condensin I complex subunit H" Q15003 2 96335766-96377091 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.2;lymphoid tissue: 37.4;testis: 35.4" "Cell type enhanced" "Detected in many" "Plasma cells: 26.3;Spermatocytes: 89.3;Spermatogonia: 29.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "T-reg: 6.2" "Group enriched" "Detected in many" 5 "granulocytes: 3.8;T-cells: 6.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA002647, HPA003008" Enhanced Supported Nucleoplasm,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol Nucleoplasm "HPA002647: AB_1078300, HPA003008: AB_1078301" "unprognostic (5.52e-2)" "unprognostic (7.37e-2)" "unprognostic (2.93e-2)" "unprognostic (2.85e-3)" "unprognostic (1.92e-1)" "unprognostic (7.51e-2)" "prognostic unfavorable (9.53e-6)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.50e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.16e-2)" "unprognostic (0.00e+0)" "unprognostic (3.00e-2)" "unprognostic (2.38e-1)" "unprognostic (2.14e-1)" "unprognostic (2.30e-2)" 1.2 0.7 0.3 9.9 0.4 35.2 1.8 0.9 0.9 1.3 0.1 7.7 5.6 0.9 0.2 6.3 0.5 1.6 0.4 0.3 0.2 0.4 1.0 1.1 20.3 0.1 0.0 0.3 0.3 0.5 0.2 5.2 0.3 0.4 9.3 1.8 1.5 0.2 0.3 4.7 6.2 2.8 0.0 3.7 3.6 35.4 0.1 37.4 0.4 0.1 22.0 2.6 2.0 0.3 134.1 52.0 115.1 60.6 3.9 6.1 80.8 58.7 40.3 115.1 118.4 93.5 71.5 121.0 41.8 26.6 106.2 57.2 100.2 39.6 117.2 110.0 63.4 123.7 49.3 74.5 0.7 112.2 101.3 1.8 4.2 89.1 35.9 10.2 46.6 89.7 89.5 88.8 53.0 59.5 183.8 104.2 85.9 57.6 56.6 133.4 106.7 95.5 23.6 49.6 71.2 52.3 34.8 46.5 19.9 42.4 36.6 80.0 24.1 83.5 126.3 76.9 101.9 44.4 70.1 134.0 33.7 111.5 95.3 3.8 0.0 0.2 0.8 0.9 0.1 0.9 1.2 1.0 0.4 0.9 0.0 0.4 0.3 0.1 0.0 0.0 6.2 0.5 0.3 0.4 0.9 0.9 0.3 0.2 0.1 0.0 0.3 0.0 0.1 0.3 4.9 0.0 0.0 0.0 3.5 0.6 0.7 1.9 1.2 0.4 1.0 0.8 0.5 0.0 1.6 0.0 8.4 9.4 2.0 2.1 0.0 0.5 5.9 1.7 0.9 1.8 0.0 16.4 0.4 0.0 16.3 1.8 4.1 1.2 1.3 5.5 1.4 0.4 8.5 0.0 0.3 2.8 0.0 3.8 3.7 4.9 0.9 2.2 1.8 0.0 0.2 8.5 0.0 0.5 1.0 0.2 0.1 0.4 26.3 0.7 0.4 0.0 1.6 2.3 0.0 0.2 3.5 89.3 29.4 8.8 0.9 1.9 5.1 0.6 5.7 1.1 NDC80 "HEC, HEC1, hsNDC80, KNTC2, TID3" ENSG00000080986 "NDC80 kinetochore complex component" O14777 18 2571557-2616635 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.2;lymphoid tissue: 29.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 63.4;Spermatocytes: 82.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 7.2;granulocytes: 8.3;T-cells: 11.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA066330 Supported Nucleoplasm,Centrosome NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Centrosome "HPA066330: AB_2685661" "unprognostic (1.96e-1)" "unprognostic (5.38e-2)" "unprognostic (2.96e-1)" "unprognostic (2.21e-3)" "unprognostic (1.87e-1)" "unprognostic (3.63e-2)" "prognostic unfavorable (2.53e-8)" "unprognostic (1.16e-2)" "unprognostic (2.58e-3)" "unprognostic (2.86e-2)" "unprognostic (3.19e-3)" "unprognostic (7.74e-2)" "unprognostic (0.00e+0)" "unprognostic (9.69e-3)" "unprognostic (1.69e-1)" "unprognostic (3.50e-2)" "unprognostic (1.71e-1)" 1.8 0.9 1.4 9.6 1.3 31.2 2.5 2.2 1.7 2.7 0.1 7.0 5.9 4.3 2.1 5.6 1.2 2.5 1.2 1.0 0.6 1.2 1.6 1.5 20.5 1.9 0.6 0.8 0.9 0.5 0.1 10.4 2.9 5.3 9.8 0.7 1.1 14.0 0.9 7.9 6.2 5.0 0.4 5.5 3.8 15.1 1.2 29.2 1.6 0.6 19.3 3.2 4.6 2.5 80.3 17.7 86.5 38.6 4.5 9.8 44.5 91.7 49.1 117.7 99.7 49.2 44.0 86.6 40.4 35.9 49.7 47.9 98.2 39.9 123.6 32.2 24.6 68.8 49.5 38.1 1.5 133.2 55.1 5.1 3.7 67.8 47.8 12.0 54.3 52.8 56.8 107.1 104.0 36.2 65.1 57.2 44.9 51.6 25.3 71.0 88.6 69.7 31.0 38.0 69.3 31.4 84.4 21.7 32.7 34.0 36.7 52.4 33.2 75.7 168.1 60.7 123.2 46.5 78.6 116.0 33.5 60.8 65.8 3.5 0.6 2.5 1.8 0.4 1.7 7.2 3.2 3.8 0.2 5.3 2.0 2.0 8.3 1.7 0.5 1.3 11.3 1.3 1.4 1.3 2.2 1.7 1.0 0.6 1.9 0.6 2.9 0.4 1.2 2.5 2.8 0.0 0.6 0.3 5.8 2.3 0.7 3.8 0.6 0.0 0.6 0.9 15.8 0.0 2.4 0.0 0.0 15.5 4.8 2.1 0.0 0.9 22.0 1.3 3.7 1.9 0.0 63.4 0.6 0.4 21.7 6.8 2.6 2.1 0.0 20.8 5.7 0.5 11.5 0.0 0.5 2.8 8.2 3.2 2.4 7.6 7.5 1.7 0.0 1.0 0.4 0.0 7.2 0.5 0.5 0.3 0.1 23.3 14.1 0.4 0.4 0.2 1.4 0.0 19.7 0.6 6.8 82.8 21.1 4.2 0.6 2.1 8.7 9.8 6.2 1.5 NDE1 "FLJ20101, NDE, nudE" ENSG00000072864 "NudE neurodevelopment protein 1" Q9NXR1 16 15643267-15734691 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis" "Developmental protein" Lissencephaly "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 105.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "granulocytes: 21.8;monocytes: 11.7;NK-cells: 8.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024075 Approved NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" "HPA024075: AB_1854336" "unprognostic (1.09e-1)" "unprognostic (1.66e-1)" "unprognostic (3.26e-1)" "unprognostic (1.47e-1)" "unprognostic (3.84e-1)" "unprognostic (4.11e-2)" "prognostic unfavorable (9.92e-4)" "unprognostic (1.43e-2)" "unprognostic (1.59e-1)" "unprognostic (4.55e-2)" "unprognostic (3.70e-3)" "unprognostic (1.16e-1)" "prognostic unfavorable (8.19e-4)" "unprognostic (1.29e-1)" "unprognostic (3.28e-2)" "unprognostic (2.22e-1)" "unprognostic (2.93e-2)" 9.2 5.8 12.1 13.0 23.6 25.6 9.4 22.5 15.6 14.6 6.9 25.0 7.5 11.6 2.6 17.7 11.1 9.8 10.6 11.2 16.1 6.3 4.2 11.1 20.4 30.0 24.5 7.5 4.0 4.0 3.1 10.0 26.5 14.2 7.3 2.0 12.2 5.1 7.3 27.6 12.9 10.7 17.0 12.5 10.1 11.1 21.3 23.4 6.3 7.9 20.9 15.3 19.8 43.2 37.0 33.0 34.2 39.9 11.4 18.6 10.4 15.4 21.0 30.4 34.5 18.3 58.3 21.9 24.0 23.2 16.7 34.5 25.3 47.3 20.8 33.7 16.0 24.6 35.3 51.7 16.3 33.3 37.2 6.6 28.9 28.8 52.0 16.9 40.6 27.9 20.5 80.5 26.6 43.9 43.0 30.5 30.5 26.5 14.3 64.8 32.3 34.8 11.6 24.1 17.0 21.0 27.5 40.7 27.6 25.9 42.8 34.3 12.5 26.9 17.6 43.2 36.1 17.4 13.1 38.1 27.5 43.0 55.0 5.1 4.7 15.0 3.0 3.8 1.7 3.3 3.0 1.3 3.4 1.9 1.8 2.0 21.8 8.5 11.7 3.1 3.3 3.9 12.1 23.6 22.5 15.6 11.2 16.1 30.0 24.5 26.5 17.0 21.3 43.2 11.7 3.2 4.4 11.1 36.1 26.0 32.7 19.0 24.5 7.0 9.5 10.4 2.0 4.3 8.9 5.5 6.2 3.9 25.0 9.6 0.0 4.5 46.9 17.1 23.1 11.6 4.2 49.0 2.1 5.3 5.3 11.8 19.4 15.0 10.8 15.5 8.6 1.7 10.1 3.3 2.4 7.4 2.0 15.8 11.0 58.5 15.8 19.3 12.4 22.5 53.0 7.4 50.4 9.5 105.5 7.1 4.2 6.0 16.6 26.3 4.6 1.9 13.3 6.5 6.6 6.9 9.5 13.8 10.0 18.8 30.7 2.5 28.3 9.8 10.2 21.6 NDUFAF4 "bA22L21.1, C6orf66, HRPAP20, HSPC125, My013" ENSG00000123545 "NADH:ubiquinone oxidoreductase complex assembly factor 4" Q9P032 6 96889315-96897891 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction" Calmodulin-binding "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 168.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046560 Uncertain Supported Mitochondria NA Yes "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA046560: AB_10966700" "prognostic unfavorable (1.31e-4)" "unprognostic (1.32e-1)" "unprognostic (1.09e-2)" "unprognostic (1.14e-3)" "unprognostic (2.89e-1)" "unprognostic (7.53e-3)" "unprognostic (6.89e-2)" "unprognostic (1.27e-1)" "unprognostic (5.57e-2)" "unprognostic (2.78e-2)" "unprognostic (2.03e-2)" "unprognostic (1.13e-1)" "unprognostic (4.20e-3)" "unprognostic (6.32e-2)" "unprognostic (1.11e-1)" "unprognostic (4.87e-2)" "unprognostic (1.31e-1)" 5.7 7.9 13.3 3.4 14.7 2.2 7.0 16.8 21.4 6.4 10.4 7.4 4.9 5.5 4.7 5.4 4.4 4.5 25.6 14.7 15.6 12.6 9.3 3.2 4.7 14.9 14.5 7.8 5.5 10.1 2.5 4.8 15.6 7.2 7.5 9.8 6.2 9.6 23.2 4.8 4.4 5.6 12.3 4.9 4.7 4.6 16.6 5.3 7.4 31.1 4.7 7.8 3.7 13.7 2.2 6.1 10.5 14.3 10.3 5.9 5.6 6.0 5.6 8.8 6.6 8.4 3.7 20.6 10.7 5.6 8.4 4.4 24.7 9.3 8.5 14.5 19.5 23.0 3.2 7.4 11.2 24.4 9.2 5.7 14.2 7.6 7.7 4.4 6.9 14.3 21.0 13.6 13.9 7.0 15.7 13.1 20.1 11.3 10.0 7.4 5.9 10.7 14.6 6.0 17.9 8.4 3.1 10.7 17.5 10.2 3.3 16.1 5.8 4.6 3.5 16.2 9.9 3.1 5.4 20.0 6.2 18.1 6.9 0.2 1.8 0.5 4.0 3.6 5.3 5.1 5.2 5.4 3.3 5.4 7.6 6.9 0.3 3.0 2.3 3.8 5.9 3.2 13.3 14.7 16.8 21.4 14.7 15.6 14.9 14.5 15.6 12.3 16.6 13.7 31.9 9.6 19.8 9.8 43.2 108.8 74.4 82.6 60.9 15.1 28.5 48.1 126.9 25.8 37.3 23.9 0.0 49.6 27.9 23.5 168.3 37.7 3.3 19.2 18.3 30.7 39.3 23.3 18.5 27.6 47.6 34.4 33.6 15.9 20.3 42.5 26.0 51.8 53.9 26.9 17.8 44.3 67.1 18.3 33.7 6.2 26.1 20.2 55.2 11.2 19.7 20.7 24.7 8.0 13.1 21.4 19.7 24.8 40.6 63.7 24.2 118.0 16.6 16.6 26.3 57.8 49.1 42.3 63.7 63.1 96.7 32.8 34.3 43.4 58.1 46.4 NECTIN2 "CD112, HVEB, PRR2, PVRL2, PVRR2" ENSG00000130202 "Nectin cell adhesion molecule 2" Q92692 19 44846175-44889223 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 136.6;Ductal cells: 215.6;Exocrine glandular cells: 154.2;Glandular and luminal cells: 126.1;Pancreatic endocrine cells: 241.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 10.4" "Lineage enhanced" "Detected in many" "granulocytes: 10.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012759, CAB026138, HPA073459" Enhanced Approved "Nucleoli fibrillar center,Cell Junctions" NA Yes 5900000 "Cluster 52: Eosinophils - Transcription" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 39: CACO-2 - Unknown function" "Cluster 7: Non-specific - Mitochondria" "Nucleoli fibrillar center, Cell Junctions" "CAB026138: , HPA012759: AB_1846227, HPA073459: " "unprognostic (3.30e-2)" "unprognostic (2.84e-1)" "unprognostic (1.07e-1)" "unprognostic (5.61e-3)" "unprognostic (7.45e-2)" "unprognostic (2.21e-1)" "unprognostic (1.66e-2)" "unprognostic (6.63e-2)" "unprognostic (2.85e-1)" "unprognostic (2.97e-1)" "unprognostic (6.93e-2)" "unprognostic (3.19e-1)" "unprognostic (1.60e-1)" "unprognostic (2.15e-1)" "unprognostic (1.61e-1)" "unprognostic (8.19e-2)" "unprognostic (2.05e-1)" 71.4 79.1 30.8 32.1 28.4 15.8 66.0 29.8 34.3 41.7 44.3 42.3 55.3 45.0 58.2 76.3 43.9 52.5 71.3 29.2 33.1 79.6 118.5 72.9 15.8 35.8 33.0 41.7 55.0 61.5 39.1 77.2 32.9 69.2 32.8 16.7 62.6 30.4 20.1 52.5 47.5 31.3 31.8 58.1 75.4 65.8 34.7 6.9 57.4 17.7 25.3 55.8 49.3 28.9 73.8 89.3 118.3 140.6 59.3 35.8 123.7 62.6 83.9 120.4 136.6 194.8 171.0 0.6 79.2 79.0 61.1 98.5 106.6 55.6 91.7 3.2 53.2 43.0 30.8 128.6 145.0 0.7 117.9 64.9 22.5 56.2 44.8 123.2 149.3 3.0 71.1 0.7 59.2 146.4 0.6 5.6 92.8 249.8 27.7 4.3 37.7 3.2 139.5 100.1 5.4 15.2 74.9 127.0 28.7 210.4 97.2 47.1 140.1 31.3 105.5 23.7 48.6 9.0 25.8 0.6 57.3 10.0 83.0 1.8 2.0 10.4 0.0 0.7 0.2 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.8 0.0 0.4 0.3 0.0 0.7 30.8 28.4 29.8 34.3 29.2 33.1 35.8 33.0 32.9 31.8 34.7 28.9 136.6 35.3 31.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 108.4 54.9 0.0 0.0 6.8 58.8 0.0 109.3 2.6 0.0 3.9 215.6 0.0 73.8 66.3 58.8 0.0 0.0 0.0 154.2 97.8 30.4 0.0 126.1 3.8 75.0 0.0 0.0 54.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.2 0.0 0.0 80.1 0.0 0.0 0.0 0.0 241.8 0.0 0.0 0.1 0.0 0.0 27.1 3.6 0.0 0.0 0.0 42.9 0.0 0.0 0.0 0.0 101.8 2.2 58.3 0.0 0.0 NEDD9 "CAS-L, CASS2, HEF1" ENSG00000111859 "Neural precursor cell expressed, developmentally down-regulated 9" Q14511 6 11183298-11382348 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell cycle, Cell division, Growth regulation, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 323.2;Alveolar cells type 1: 471.1;Glandular and luminal cells: 337.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 137.3;HSkMC: 67.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009689, CAB009720, HPA038768, HPA039270, HPA072955" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB009720: , HPA009689: , HPA038768: AB_2676196, HPA039270: AB_2676422, HPA072955: " "unprognostic (2.83e-3)" "unprognostic (2.33e-2)" "unprognostic (1.08e-2)" "unprognostic (6.93e-2)" "unprognostic (2.12e-1)" "unprognostic (1.16e-1)" "unprognostic (1.62e-1)" "unprognostic (9.54e-2)" "unprognostic (3.05e-2)" "unprognostic (2.09e-1)" "unprognostic (2.90e-1)" "unprognostic (1.64e-1)" "unprognostic (5.59e-3)" "unprognostic (2.25e-2)" "unprognostic (2.37e-1)" "unprognostic (2.41e-1)" "unprognostic (1.05e-1)" 94.7 8.6 8.3 23.3 8.1 8.6 64.2 6.4 12.3 26.6 14.4 30.7 15.5 19.2 17.5 14.5 22.7 31.4 32.7 7.7 6.4 33.8 20.7 91.9 25.8 8.3 7.3 8.3 17.1 9.5 8.1 69.2 8.5 22.4 30.2 9.8 26.7 29.8 27.2 20.6 38.1 25.8 7.4 25.2 23.5 6.9 9.7 22.2 25.6 12.0 22.2 34.5 15.3 7.9 4.4 29.0 26.4 0.4 17.7 2.3 27.7 6.6 8.2 12.2 22.4 9.3 1.9 9.2 137.3 14.7 1.5 12.6 36.0 13.5 15.8 4.1 1.0 0.8 4.4 62.3 8.3 10.1 0.4 67.7 4.0 7.9 1.3 4.4 21.0 0.8 0.1 7.6 27.7 1.3 5.8 4.0 4.1 34.6 2.9 1.6 0.7 5.4 6.1 39.8 0.6 4.8 1.1 31.2 55.5 29.3 2.3 7.7 53.8 8.2 14.3 0.8 16.5 7.8 34.8 11.4 0.2 7.9 36.6 24.2 13.3 37.3 18.3 28.5 14.7 10.9 12.2 17.5 14.1 12.3 6.4 9.9 80.9 12.3 50.6 8.7 12.1 17.1 8.3 8.1 6.4 12.3 7.7 6.4 8.3 7.3 8.5 7.4 9.7 7.9 323.2 471.1 135.1 11.1 34.9 60.5 235.6 83.5 98.4 4.7 43.1 38.0 14.2 50.1 89.0 44.1 25.0 56.3 45.9 103.4 9.8 62.0 8.2 244.8 24.8 148.1 108.3 2.5 18.2 19.8 42.6 37.2 107.6 337.0 64.5 15.7 86.7 21.6 14.7 10.1 11.3 108.4 12.2 29.8 28.9 4.3 7.5 51.4 24.9 34.7 15.4 84.1 64.9 8.0 4.9 69.1 43.6 29.0 34.8 66.1 100.5 26.7 64.4 12.4 26.3 8.8 30.0 2.1 1.1 11.4 20.6 42.8 59.4 37.2 46.6 90.3 NEIL3 "FLJ10858, FPG2, hFPG2, hNEI3, ZGRF3" ENSG00000109674 "Nei like DNA glycosylase 3" Q8TAT5 4 177309874-177362936 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Glycosidase, Hydrolase, Lyase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 6.6;lymphoid tissue: 23.6" "Cell type enhanced" "Detected in some" "Erythroid cells: 14.7;Granulosa cells: 4.8;Plasma cells: 6.1;Squamous epithelial cells: 4.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 72.1;HL-60: 79.1;Karpas-707: 99.1;MOLT-4: 80.7" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 3.3" HPA065761 Enhanced Nucleoplasm NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA065761: AB_2685555" "unprognostic (6.03e-2)" "unprognostic (5.79e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (5.45e-4)" "unprognostic (4.91e-2)" "unprognostic (2.05e-1)" "unprognostic (3.64e-7)" "prognostic unfavorable (1.16e-4)" "unprognostic (6.09e-3)" "unprognostic (7.67e-2)" "unprognostic (6.51e-4)" "unprognostic (2.82e-3)" "unprognostic (0.00e+0)" "unprognostic (3.25e-2)" "unprognostic (8.13e-2)" "unprognostic (2.03e-1)" "unprognostic (1.04e-2)" 0.1 0.0 0.0 1.7 0.0 6.6 0.3 0.0 0.1 0.2 0.0 1.1 1.1 0.1 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 3.6 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.5 0.0 0.2 0.0 0.0 2.3 1.3 0.5 0.0 0.4 0.6 1.5 0.1 23.6 0.0 0.0 3.5 0.4 0.4 0.0 19.3 15.8 16.4 8.2 1.8 3.3 8.0 23.4 8.6 25.3 14.9 5.8 16.5 21.2 3.4 6.2 25.1 8.8 17.4 9.3 36.6 72.1 11.4 14.7 11.9 15.2 0.5 79.1 9.7 0.3 0.5 26.2 5.6 5.2 9.9 53.9 15.3 99.1 16.7 8.4 80.7 30.2 7.5 5.7 11.5 16.2 11.2 6.8 6.8 2.6 12.8 8.9 11.7 13.4 6.3 7.2 10.9 20.4 4.7 15.2 11.8 7.8 24.0 6.8 4.8 33.5 10.1 27.8 24.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.1 0.4 1.2 0.0 0.2 0.1 0.4 0.0 1.3 0.0 0.0 2.6 1.6 0.5 0.0 0.0 0.1 0.1 0.6 0.3 0.0 14.7 0.1 0.2 3.3 0.9 0.0 0.5 0.0 4.8 0.4 0.0 1.5 0.0 0.1 1.0 0.0 1.3 0.4 0.2 0.0 1.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.7 6.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.5 2.7 2.4 4.5 1.3 0.3 1.0 0.5 1.2 0.2 NEK2 "NEK2A, NLK1, PPP1R111, RP67" ENSG00000117650 "NIMA related kinase 2" P51955 1 211658657-211675630 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 17.9;lymphoid tissue: 19.2;testis: 67.1" "Group enriched" "Detected in many" 4 "Early spermatids: 76.1;Spermatocytes: 244.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 5.7" "Low region specificity" "Detected in all" "CAB017530, HPA064967" Enhanced Supported Nucleoplasm,Centrosome NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Centrosome" "CAB017530: AB_1126558, HPA064967: AB_2685393" "unprognostic (1.28e-1)" "unprognostic (2.33e-1)" "unprognostic (1.02e-1)" "unprognostic (8.51e-2)" "unprognostic (1.83e-1)" "unprognostic (1.35e-2)" "prognostic unfavorable (9.47e-6)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.95e-2)" "unprognostic (2.00e-2)" "unprognostic (1.09e-3)" "unprognostic (8.49e-2)" "unprognostic (0.00e+0)" "unprognostic (8.21e-2)" "unprognostic (4.11e-2)" "unprognostic (1.25e-2)" "unprognostic (2.71e-1)" 0.7 0.4 0.5 5.3 0.4 17.9 1.5 0.9 0.6 1.1 0.6 5.9 7.4 1.3 0.5 4.4 2.2 0.8 0.4 0.5 0.3 0.3 0.7 0.7 9.0 0.4 0.2 0.4 0.1 0.1 0.0 3.2 0.3 2.5 7.6 1.5 0.8 0.2 0.4 4.3 6.9 2.0 0.2 1.7 2.7 67.1 0.6 19.2 0.4 0.2 10.6 1.3 1.6 0.9 86.0 60.5 45.3 32.6 2.6 4.5 49.7 32.4 30.1 55.4 47.5 32.3 81.7 45.1 15.2 25.2 35.1 44.5 39.9 24.2 69.6 69.5 33.2 21.6 51.4 44.2 0.4 43.2 28.3 1.4 2.9 42.9 45.9 13.4 36.3 45.2 59.9 76.9 56.0 23.6 47.3 28.8 43.0 55.0 30.5 46.2 69.2 68.7 19.7 24.2 41.0 45.0 46.6 51.5 39.3 38.4 79.4 25.1 19.0 27.6 54.1 54.8 88.3 31.6 62.6 59.6 24.1 32.6 46.8 1.2 0.1 0.1 0.1 0.1 0.0 0.5 0.1 0.1 0.0 0.4 0.3 0.2 0.7 1.5 0.1 0.2 1.6 0.3 0.5 0.4 0.9 0.6 0.5 0.3 0.4 0.2 0.3 0.2 0.6 0.9 0.1 0.0 0.5 0.3 1.7 2.9 0.7 3.8 0.6 11.3 1.9 2.2 0.5 0.0 2.9 0.0 0.0 9.4 0.8 1.9 0.0 0.2 76.1 15.2 0.7 0.8 0.0 39.6 0.8 0.2 14.1 1.4 5.6 1.5 0.0 3.6 3.6 0.7 5.8 3.3 0.0 3.2 10.2 2.5 1.1 39.0 2.5 2.1 0.0 0.0 0.0 1.6 2.1 0.0 0.1 0.0 2.5 0.7 5.4 0.7 2.1 0.1 5.2 1.8 6.6 0.0 1.5 244.2 26.1 8.6 1.7 1.4 2.0 0.9 9.5 1.4 NET1 "ARHGEF8, NET1A" ENSG00000173848 "Neuroepithelial cell transforming 1" Q7Z628 10 5412557-5459056 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 242.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 8.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 252.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020068 Uncertain Approved Nucleoplasm,Vesicles Yes Yes "Cluster 32: T-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA020068: AB_2670348" "unprognostic (1.77e-2)" "unprognostic (1.87e-1)" "unprognostic (3.40e-1)" "unprognostic (4.05e-2)" "unprognostic (3.37e-3)" "unprognostic (2.15e-1)" "prognostic unfavorable (3.87e-5)" "unprognostic (6.31e-2)" "unprognostic (1.87e-1)" "unprognostic (2.77e-2)" "prognostic unfavorable (8.27e-4)" "unprognostic (2.26e-1)" "unprognostic (5.41e-2)" "unprognostic (1.20e-1)" "unprognostic (1.90e-1)" "unprognostic (3.01e-1)" "unprognostic (2.46e-1)" 48.8 10.8 35.5 23.4 34.2 40.5 52.8 38.5 57.6 43.7 52.8 92.2 56.2 41.8 56.2 68.4 46.2 35.9 13.2 30.2 32.4 49.3 45.1 22.2 26.7 41.8 37.2 28.5 37.9 5.4 10.6 65.7 43.8 41.3 88.2 6.5 93.1 24.3 25.0 39.8 74.7 36.9 37.5 8.1 77.8 14.4 41.1 30.4 26.2 28.0 33.0 60.8 59.3 40.1 115.9 67.7 45.2 51.0 26.8 11.9 252.9 69.1 37.6 53.4 50.4 36.4 215.2 40.6 27.7 42.4 11.4 185.5 54.9 104.3 63.9 38.1 38.5 77.5 22.9 84.0 7.2 21.5 31.1 18.2 61.0 54.0 12.3 47.6 31.1 42.6 138.5 64.4 30.0 54.3 74.3 30.6 61.5 158.6 51.0 45.0 85.0 32.4 33.4 57.6 38.5 20.6 60.7 110.9 20.3 76.2 36.7 65.3 29.5 20.3 30.9 30.7 56.0 39.3 23.1 53.4 18.1 33.1 43.4 2.0 0.6 1.4 0.6 1.0 0.0 1.4 1.2 0.4 4.9 0.6 8.7 1.7 0.1 0.8 0.4 2.0 4.0 2.2 35.5 34.2 38.5 57.6 30.2 32.4 41.8 37.2 43.8 37.5 41.1 40.1 18.4 32.1 55.8 2.6 12.7 40.3 127.2 49.0 103.0 11.0 52.6 28.3 12.1 41.5 84.3 12.9 4.2 110.2 8.4 242.2 5.9 13.1 2.4 97.7 30.6 42.7 80.8 54.1 5.1 24.4 109.1 33.2 107.0 131.4 15.2 16.9 12.5 55.7 14.5 3.3 7.7 145.3 34.6 10.5 59.8 2.4 21.8 31.2 35.6 44.0 48.7 3.8 0.0 8.5 5.7 62.1 148.3 87.6 39.2 67.8 123.6 29.2 85.7 3.5 111.7 183.0 185.0 26.3 16.0 158.1 32.4 117.5 9.3 2.9 145.0 186.5 NEURL1B "DKFZP761M1511, Neur2, RNF67B" ENSG00000214357 "Neuralized E3 ubiquitin protein ligase 1B" A8MQ27 5 172641263-172691540 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 82.8;Distal enterocytes: 82.5;Endothelial cells: 53.8;Leydig cells: 54.7;Paneth cells: 42.1;Proximal enterocytes: 53.4;Smooth muscle cells: 58.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "REH: 43.7;T-47d: 20.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037612 Approved Supported "Actin filaments,Cytosol" NA Yes "Cluster 46: Fibroblasts - ECM organization" "Cluster 14: REH - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Actin filaments" "HPA037612: AB_10795573" "unprognostic (3.56e-2)" "unprognostic (8.46e-2)" "unprognostic (6.72e-3)" "unprognostic (2.70e-1)" "unprognostic (1.64e-1)" "unprognostic (1.55e-1)" "unprognostic (6.58e-2)" "unprognostic (2.95e-1)" "unprognostic (2.86e-1)" "unprognostic (1.09e-1)" "unprognostic (7.13e-3)" "unprognostic (6.81e-2)" "prognostic unfavorable (3.00e-6)" "unprognostic (1.79e-1)" "unprognostic (1.40e-1)" "unprognostic (4.67e-2)" "unprognostic (3.22e-3)" 25.0 16.0 8.4 5.2 10.3 2.0 21.1 2.3 24.1 18.3 3.4 28.4 6.9 24.7 24.1 13.5 22.0 11.7 32.2 17.1 6.9 11.0 6.0 12.6 3.7 3.5 4.6 14.7 5.3 3.2 8.2 6.1 3.8 17.6 13.7 0.3 6.6 32.1 14.0 18.1 17.6 20.4 3.6 0.7 7.7 4.3 6.3 5.9 10.3 16.0 3.9 25.7 17.3 6.5 7.2 3.7 2.0 8.9 0.6 0.3 0.1 8.0 3.5 4.1 6.0 13.7 3.2 0.0 2.1 5.2 5.0 2.1 0.7 3.6 2.8 13.2 0.5 9.8 13.3 0.1 0.6 0.0 2.9 0.0 15.1 0.9 4.1 1.2 0.6 1.4 0.0 3.0 8.9 8.0 2.3 0.2 1.3 3.1 0.3 43.7 9.4 1.4 0.1 1.6 1.6 8.9 7.6 11.9 0.3 3.5 20.0 1.5 1.3 3.1 18.1 2.2 5.1 1.2 0.4 0.0 9.0 0.2 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 10.3 2.3 24.1 17.1 6.9 3.5 4.6 3.8 3.6 6.3 6.5 82.8 0.0 1.9 0.3 0.6 4.8 0.7 3.0 0.6 0.6 1.5 1.3 9.3 1.5 4.8 0.0 0.0 0.3 0.4 82.5 0.0 0.7 2.6 1.9 2.5 53.8 13.9 11.4 5.2 0.7 0.2 10.3 2.0 0.6 0.0 4.9 30.4 0.3 0.3 0.0 1.0 10.2 2.0 1.9 2.6 6.6 54.7 2.2 7.2 4.7 0.7 0.7 0.0 5.0 13.0 4.5 42.1 12.4 0.1 1.9 53.4 0.8 12.8 0.3 26.3 11.6 58.8 2.5 3.4 7.7 5.4 0.1 0.7 2.5 20.0 1.2 NOL4L "C20orf112, C20orf113, dJ1184F4.2, dJ1184F4.4, DKFZP566G1424" ENSG00000197183 "Nucleolar protein 4 like" Q96MY1 20 32443059-32585074 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 49.3;testis: 50.0" "Cell type enhanced" "Detected in many" "Early spermatids: 107.4;Late spermatids: 171.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CACO-2: 73.4;HEL: 58.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041768, HPA043600" Enhanced Enhanced Nucleoplasm NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 77: Retina - Visual perception" "Cluster 39: CACO-2 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA041768: AB_10964172, HPA043600: AB_10961001" "unprognostic (4.33e-2)" "unprognostic (1.71e-1)" "unprognostic (4.03e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (3.10e-1)" "unprognostic (7.88e-2)" "unprognostic (2.75e-3)" "unprognostic (1.65e-2)" "unprognostic (1.83e-1)" "unprognostic (1.41e-1)" "unprognostic (1.84e-1)" "unprognostic (1.72e-1)" "unprognostic (3.88e-2)" "unprognostic (9.32e-2)" "unprognostic (3.42e-1)" "unprognostic (6.08e-3)" "prognostic favorable (2.63e-4)" 10.4 9.1 12.8 8.7 17.5 20.8 10.2 20.8 19.9 8.7 3.1 17.2 18.7 6.6 12.0 2.5 8.6 8.6 5.6 13.2 14.7 14.5 7.0 13.4 8.0 14.5 13.5 4.0 11.1 4.3 22.3 11.1 14.8 8.7 13.6 49.3 9.7 8.2 1.6 3.5 19.8 6.5 10.3 12.9 13.2 50.0 13.1 15.1 9.7 1.7 5.8 9.7 5.2 19.5 9.1 27.4 16.9 11.6 3.6 5.4 2.3 5.7 4.6 7.1 4.9 73.4 20.8 0.6 16.6 7.5 11.0 2.5 5.4 15.9 3.2 2.1 4.3 58.2 14.5 53.2 9.3 0.9 3.3 13.6 2.2 5.2 3.4 16.1 43.1 12.5 17.7 7.6 3.4 5.1 19.3 17.8 9.9 27.7 25.3 8.2 2.1 3.0 12.0 1.6 22.3 18.1 17.9 0.4 9.8 17.4 3.7 17.8 45.5 6.6 22.6 6.1 5.9 5.6 2.1 4.0 7.2 31.4 20.3 2.9 2.0 1.2 5.8 4.5 5.1 1.6 3.8 3.4 2.1 1.1 7.6 6.4 6.5 8.3 12.1 0.2 6.9 4.9 12.8 17.5 20.8 19.9 13.2 14.7 14.5 13.5 14.8 10.3 13.1 19.5 23.1 6.4 3.3 7.2 4.1 0.0 10.8 0.0 2.2 49.9 20.8 18.3 8.8 11.5 1.3 12.9 66.7 0.3 29.5 57.9 9.8 8.0 107.4 9.4 2.9 25.3 17.5 4.6 29.7 7.8 2.1 5.8 20.4 8.7 12.0 11.1 21.8 4.7 9.8 8.4 22.0 36.6 0.0 3.3 0.0 171.5 5.6 8.6 0.0 33.7 6.1 17.2 24.7 14.1 51.2 14.0 36.6 4.9 9.0 15.2 59.4 24.0 2.2 57.3 19.7 1.7 5.0 75.3 3.8 0.8 0.0 0.4 16.5 16.9 29.5 28.7 NOL7 "C6orf90, dJ223E5.2, NOP27, PQBP3, RARG-1" ENSG00000225921 "Nucleolar protein 7" Q9UMY1 6 13615335-13632739 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029185 Supported Supported "Nucleoli,Mitotic chromosome,Mitochondria" Yes Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Mitotic chromosome" Mitochondria "HPA029185: AB_10601274" "unprognostic (8.76e-2)" "unprognostic (8.94e-2)" "unprognostic (8.38e-2)" "unprognostic (1.15e-2)" "unprognostic (3.75e-1)" "unprognostic (5.77e-2)" "unprognostic (2.50e-3)" "unprognostic (1.57e-1)" "unprognostic (4.64e-2)" "prognostic favorable (3.64e-5)" "unprognostic (1.26e-1)" "unprognostic (2.03e-2)" "unprognostic (8.04e-3)" "unprognostic (2.58e-1)" "unprognostic (1.17e-1)" "unprognostic (4.86e-2)" "unprognostic (4.79e-2)" 44.3 43.9 29.5 21.7 30.8 29.5 42.0 32.2 34.0 37.5 28.2 44.8 26.8 37.7 23.4 38.2 35.5 16.6 48.2 28.7 31.1 58.5 37.9 32.2 25.8 30.9 31.4 40.7 48.9 40.2 35.9 21.1 31.0 35.1 19.8 16.6 38.0 19.2 44.5 36.9 36.4 16.0 30.8 37.8 37.9 41.7 30.7 15.2 37.1 17.1 20.3 41.4 34.9 33.8 71.7 37.2 31.7 42.7 26.9 26.1 74.4 71.8 29.3 48.4 44.4 60.0 24.9 97.8 137.4 34.4 57.7 46.5 46.9 42.4 47.8 57.5 105.0 91.2 36.3 104.0 45.4 112.0 61.4 25.5 41.5 42.5 24.2 29.8 33.6 45.5 135.7 22.2 44.7 38.1 70.6 147.6 42.1 37.0 74.1 74.4 46.8 140.5 57.9 21.7 92.5 60.3 40.9 88.0 94.9 36.2 53.6 42.8 65.7 48.0 51.9 57.8 108.3 66.2 123.2 100.2 30.7 70.7 75.6 34.5 59.6 82.1 59.2 76.4 68.2 104.0 84.7 71.4 73.2 87.8 90.7 69.0 27.4 61.9 82.9 91.4 96.0 67.9 29.5 30.8 32.2 34.0 28.7 31.1 30.9 31.4 31.0 30.8 30.7 33.8 103.1 93.0 73.5 10.4 112.5 90.8 117.3 151.0 50.1 62.1 78.9 97.0 214.9 68.6 112.0 57.0 22.9 137.4 71.5 72.7 123.3 188.7 202.3 105.8 95.0 109.2 37.1 89.4 14.0 261.2 153.8 90.9 58.1 91.6 90.6 67.0 61.1 61.8 115.1 48.8 17.1 97.8 130.2 52.6 81.8 38.9 82.6 78.5 101.4 8.4 119.7 124.2 78.2 13.6 19.0 175.0 94.3 79.4 138.8 121.7 81.2 163.6 135.6 61.7 65.7 92.5 119.4 186.3 112.9 70.8 90.5 155.3 99.5 99.2 91.0 117.2 NOLC1 "KIAA0035, NOPP130, NOPP140, P130, Srp40" ENSG00000166197 "Nucleolar and coiled-body phosphoprotein 1" Q14978 10 102152176-102163871 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032654, HPA037366, HPA050388" Supported Enhanced "Nucleoli fibrillar center" No Yes 44000 "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli fibrillar center" "CAB032654: AB_2152006, HPA037366: AB_10670930, HPA050388: AB_2681109" "unprognostic (3.23e-1)" "unprognostic (5.58e-2)" "unprognostic (9.44e-2)" "unprognostic (9.13e-2)" "unprognostic (8.89e-2)" "unprognostic (7.03e-3)" "unprognostic (2.36e-3)" "unprognostic (7.34e-3)" "unprognostic (3.43e-1)" "unprognostic (3.74e-1)" "unprognostic (5.64e-3)" "unprognostic (3.73e-2)" "prognostic unfavorable (9.19e-5)" "unprognostic (3.15e-2)" "unprognostic (3.73e-1)" "prognostic unfavorable (8.25e-5)" "unprognostic (7.68e-2)" 36.5 23.9 10.7 41.9 12.3 37.2 32.3 14.6 20.5 27.1 4.5 31.8 21.8 30.3 18.7 33.3 34.4 29.0 24.0 12.6 18.2 21.4 37.5 24.9 43.1 10.9 14.4 34.4 38.4 42.9 14.6 38.3 11.9 31.5 39.1 38.0 26.3 26.6 45.3 21.9 22.8 33.8 10.8 27.6 27.4 19.3 12.2 54.2 37.6 46.4 55.7 64.2 19.6 18.3 202.1 175.1 98.2 209.0 84.7 66.0 166.6 108.5 87.8 150.1 130.5 302.1 132.4 401.5 118.1 69.5 73.9 225.1 285.0 236.1 173.3 127.0 194.8 267.9 143.6 200.3 112.0 389.8 122.8 86.3 169.8 158.3 328.7 94.5 96.5 194.3 286.6 172.6 102.6 170.3 373.7 95.0 196.5 150.7 137.1 277.3 261.6 233.3 100.2 123.5 148.3 141.9 103.5 124.1 144.5 95.6 207.5 99.3 79.3 67.7 93.5 81.3 256.9 165.5 254.4 442.4 110.5 422.7 60.7 2.4 12.5 11.6 20.4 14.4 24.9 16.6 16.1 19.2 16.2 12.1 18.5 22.6 1.3 17.3 17.2 12.4 13.0 17.9 10.7 12.3 14.6 20.5 12.6 18.2 10.9 14.4 11.9 10.8 12.2 18.3 47.8 60.9 74.7 6.2 47.6 120.4 112.6 37.7 101.9 20.8 52.6 48.0 35.3 20.0 68.2 16.5 14.6 49.2 29.1 28.3 25.4 42.2 29.0 38.5 56.3 47.3 27.6 56.8 8.8 23.1 62.7 63.9 43.3 73.1 44.2 28.6 16.8 23.4 27.1 10.1 7.9 38.3 18.3 11.2 46.0 9.7 23.0 26.8 26.6 4.7 22.9 15.1 32.0 2.5 6.8 48.8 21.0 21.1 62.3 89.5 10.2 19.9 56.6 20.0 6.6 85.8 58.9 32.1 53.5 103.3 117.5 48.6 44.5 40.1 49.1 100.5 NOP58 "HSPC120, NOP5" ENSG00000055044 "NOP58 ribonucleoprotein" Q9Y2X3 2 202265736-202303661 "Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018472, HPA021062" Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center" NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoli fibrillar center" Nucleoplasm "HPA018472: AB_1854564, HPA021062: AB_1854565" "unprognostic (1.56e-2)" "unprognostic (1.61e-1)" "unprognostic (9.20e-2)" "unprognostic (2.15e-3)" "unprognostic (2.39e-1)" "unprognostic (3.94e-2)" "prognostic unfavorable (1.97e-6)" "unprognostic (6.64e-2)" "unprognostic (1.17e-2)" "prognostic favorable (9.86e-4)" "unprognostic (4.52e-3)" "unprognostic (5.20e-2)" "prognostic unfavorable (3.38e-9)" "unprognostic (1.79e-2)" "unprognostic (3.10e-1)" "unprognostic (1.33e-1)" "unprognostic (2.60e-1)" 36.0 35.1 33.5 43.9 33.6 76.3 43.7 38.8 58.4 29.5 33.4 30.4 28.2 32.2 33.4 37.8 31.6 23.6 25.1 33.4 36.3 32.8 40.7 26.4 60.3 32.3 33.3 37.4 37.8 24.8 30.2 32.6 32.6 29.5 35.8 28.1 26.5 23.1 41.8 30.7 29.7 27.3 32.6 33.9 29.6 24.9 34.8 41.9 27.1 21.5 59.8 43.3 30.2 35.3 126.4 86.0 85.1 106.8 62.0 55.6 199.2 118.5 62.9 89.1 82.9 191.5 110.9 193.1 95.4 72.5 111.6 114.0 170.1 144.7 158.4 75.0 152.5 233.6 133.3 193.7 91.5 234.7 108.6 72.1 85.3 124.6 284.6 48.6 81.2 112.3 260.4 144.1 113.4 131.4 215.1 258.7 212.9 139.4 146.5 179.5 128.3 257.1 107.1 148.5 130.5 95.8 109.0 156.6 140.8 136.2 106.4 181.8 70.3 113.5 133.8 102.5 206.0 115.7 226.1 274.8 84.2 163.7 138.5 13.4 24.0 7.4 37.2 35.6 55.0 56.1 53.1 51.2 37.4 45.0 57.5 58.9 2.3 52.1 28.3 53.1 58.0 32.5 33.5 33.6 38.8 58.4 33.4 36.3 32.3 33.3 32.6 32.6 34.8 35.3 56.3 109.0 116.2 22.2 111.6 85.8 150.5 98.0 78.0 28.1 53.8 70.2 82.7 37.1 116.8 40.5 41.7 78.1 87.1 35.7 29.4 59.9 39.2 59.6 75.9 62.3 35.2 65.2 39.0 67.8 96.9 82.6 51.0 97.0 137.3 47.7 32.2 46.1 47.7 25.2 47.5 61.5 61.1 23.2 43.5 11.1 43.2 51.5 24.9 20.6 59.6 18.8 35.0 20.6 27.0 50.3 17.3 29.7 118.6 89.9 18.3 37.8 70.6 44.2 26.3 112.2 116.8 70.4 58.4 77.5 74.7 68.0 124.1 45.4 79.6 94.6 NPM1 "B23, NPM" ENSG00000181163 "Nucleophosmin 1" P06748 5 171387116-171411810 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction" "Chaperone, RNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011384, CAB012983" Supported Enhanced "Nucleoplasm,Nucleoli rim" NA Yes 2000000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 32: Non-specific - Translation" "Nucleoli rim" Nucleoplasm "CAB012983: AB_2533084, HPA011384: AB_1854692" "unprognostic (1.84e-3)" "unprognostic (2.59e-1)" "unprognostic (2.23e-2)" "unprognostic (3.30e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (7.48e-4)" "prognostic unfavorable (4.82e-6)" "unprognostic (1.86e-2)" "unprognostic (5.25e-3)" "unprognostic (1.39e-1)" "unprognostic (2.26e-3)" "unprognostic (1.27e-1)" "prognostic unfavorable (2.89e-6)" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "unprognostic (1.52e-1)" "unprognostic (1.24e-2)" 515.1 370.6 180.7 468.4 190.3 789.2 597.1 188.6 233.5 759.2 195.9 486.6 347.1 656.6 421.5 623.0 596.1 355.4 336.7 169.0 210.7 375.3 370.3 364.5 777.0 196.2 188.6 1384.6 810.6 278.0 314.4 423.7 207.5 386.2 421.2 161.3 385.2 318.5 450.9 386.6 374.1 436.0 213.9 358.1 467.8 284.7 202.6 683.3 510.1 282.4 761.7 524.9 565.4 204.5 2476.2 1522.7 1864.0 2663.1 1073.3 1915.6 2736.9 2111.3 1826.0 2678.1 2387.2 3640.2 1622.2 6243.9 1683.2 1194.5 1927.6 1386.6 2552.2 4639.2 3423.4 2027.9 2027.3 2149.1 1361.9 2740.2 1593.2 4556.3 1790.7 1732.2 1559.7 1845.8 3572.3 2184.3 2019.4 1460.9 2712.8 1406.5 1945.5 2826.5 3071.1 3087.4 2400.7 1280.7 1857.2 2695.2 2051.7 3241.9 2306.9 1583.1 1433.8 1167.4 1210.6 2084.4 4091.0 1288.7 2513.8 2000.7 1289.5 916.7 2114.4 1082.5 3705.3 1161.5 2139.6 3702.2 1403.3 3561.5 1897.0 153.6 287.1 92.3 443.1 311.4 834.2 847.9 832.8 654.3 564.2 634.9 1189.9 973.4 38.0 656.2 264.4 516.8 782.6 1076.1 180.7 190.3 188.6 233.5 169.0 210.7 196.2 188.6 207.5 213.9 202.6 204.5 462.2 346.1 461.1 12.4 911.0 1400.1 1224.1 1692.5 993.1 177.2 779.0 1045.4 243.5 514.8 764.5 323.7 43.8 1647.8 615.9 175.3 743.4 1073.6 135.8 466.3 707.3 568.2 362.1 865.5 15.6 919.2 2021.0 685.9 489.8 544.6 443.8 688.8 383.8 254.1 1071.0 127.9 20.3 656.0 679.5 629.2 817.6 98.6 974.9 557.2 610.1 19.7 862.8 339.2 476.8 14.6 21.2 922.5 370.1 649.9 671.6 1051.5 404.2 911.0 357.4 144.1 433.9 617.8 1074.1 855.7 578.6 907.2 1019.1 1538.8 865.1 1019.5 866.2 967.3 NR1D1 "ear-1, hRev, Rev-ErbAalpha, REVERBA, REVERBalpha, THRA1, THRAL" ENSG00000126368 "Nuclear receptor subfamily 1 group D member 1" P20393 17 40092793-40100589 "Metabolic proteins, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 325.5" "Cell type enhanced" "Detected in all" "Squamous epithelial cells: 95.5;Suprabasal keratinocytes: 81.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 18.5" "Group enriched" "Detected in many" 6 "monocytes: 5.5;T-cells: 18.5" "Cell line enhanced" "Detected in all" "Karpas-707: 60.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007935 Uncertain Supported "Nuclear bodies" NA Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 2: Karpas-707 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear bodies" "HPA007935: AB_10601277" "unprognostic (1.38e-2)" "unprognostic (3.46e-2)" "prognostic unfavorable (1.94e-4)" "unprognostic (2.53e-1)" "unprognostic (2.24e-2)" "unprognostic (1.05e-1)" "unprognostic (4.50e-2)" "unprognostic (1.03e-1)" "prognostic favorable (1.36e-4)" "unprognostic (1.93e-3)" "unprognostic (9.93e-3)" "unprognostic (2.73e-1)" "unprognostic (9.15e-3)" "unprognostic (4.54e-3)" "unprognostic (2.49e-1)" "unprognostic (3.09e-1)" "unprognostic (1.34e-1)" 72.3 53.7 23.5 6.3 27.0 5.4 63.1 52.9 49.7 109.6 10.6 53.3 14.3 35.8 4.5 42.5 27.7 7.1 60.8 24.9 17.2 38.0 43.2 49.2 9.3 18.1 20.9 71.3 24.3 9.0 32.0 6.0 15.9 40.5 4.0 50.4 52.9 16.3 99.0 325.5 23.0 7.5 12.9 11.6 31.5 12.5 34.0 6.3 32.1 38.1 5.4 42.5 96.5 25.2 5.5 7.8 1.6 6.2 9.0 6.2 2.2 11.9 19.5 3.9 4.9 5.1 19.5 6.7 6.9 13.8 12.9 15.4 4.1 18.0 2.9 5.6 4.1 4.8 7.9 13.5 14.6 7.2 6.9 13.5 12.8 13.3 28.2 12.6 4.9 7.7 7.2 60.6 3.8 3.8 10.7 6.1 3.0 10.8 12.3 7.5 2.2 20.7 5.4 4.9 5.1 2.9 7.6 9.7 12.4 2.7 4.6 5.8 4.7 17.2 16.7 14.1 9.5 21.5 35.7 2.6 23.4 4.0 13.6 0.0 0.5 0.0 4.4 2.0 18.5 1.7 5.5 6.4 1.1 2.1 4.8 3.5 0.2 1.0 5.5 1.4 8.0 1.8 23.5 27.0 52.9 49.7 24.9 17.2 18.1 20.9 15.9 12.9 34.0 25.2 16.4 3.2 2.0 17.3 5.7 64.5 47.5 20.5 67.2 71.4 9.4 15.1 5.7 8.6 11.9 1.8 4.2 2.6 4.9 26.0 7.9 16.1 2.3 25.4 30.6 18.6 8.3 3.6 7.1 11.8 1.2 26.5 31.1 64.2 2.5 2.7 6.8 31.8 2.5 42.1 6.2 7.2 8.2 3.4 19.4 1.5 21.8 7.7 19.6 8.4 1.2 39.0 5.2 5.0 1.2 26.0 14.7 38.7 10.5 35.4 58.8 7.9 5.0 29.7 6.6 9.6 19.4 2.0 11.1 95.5 81.1 2.3 11.9 13.7 6.0 28.7 NR2F6 "EAR-2, EAR2, ERBAL2" ENSG00000160113 "Nuclear receptor subfamily 2 group F member 6" P10588 19 17231883-17245919 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 104.0" "Cell type enhanced" "Detected in all" "Distal enterocytes: 206.0;Hepatocytes: 148.4;Horizontal cells: 151.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 187.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB079917 Supported "Nuclear speckles,Cytosol" NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles" Cytosol "CAB079917: AB_2635238" "unprognostic (1.48e-1)" "unprognostic (1.30e-1)" "unprognostic (2.17e-1)" "prognostic unfavorable (4.36e-4)" "unprognostic (1.08e-1)" "unprognostic (1.12e-1)" "unprognostic (3.07e-1)" "unprognostic (3.67e-1)" "unprognostic (7.20e-2)" "unprognostic (1.02e-2)" "unprognostic (2.39e-1)" "unprognostic (6.62e-2)" "unprognostic (9.68e-2)" "unprognostic (1.31e-1)" "unprognostic (2.29e-2)" "unprognostic (7.28e-3)" "unprognostic (1.37e-3)" 17.0 21.8 19.3 5.0 16.9 1.2 17.7 15.8 22.8 18.8 23.8 39.4 31.2 19.8 14.3 47.4 19.1 2.9 39.0 16.8 20.2 32.8 104.0 17.5 1.7 23.9 21.4 12.1 44.6 10.4 22.0 13.1 18.6 25.3 9.3 6.6 28.0 9.8 27.9 23.9 25.4 4.5 17.5 9.9 38.6 14.3 20.4 1.8 21.6 9.9 2.7 25.5 22.2 15.6 65.0 38.1 20.3 37.2 7.9 8.8 187.2 35.7 12.9 15.2 13.1 26.1 55.5 15.2 108.8 16.0 8.9 31.9 15.6 20.5 6.7 20.4 90.0 13.9 24.4 47.3 17.3 6.7 18.8 11.6 23.2 7.0 11.3 15.9 9.5 6.8 33.3 3.7 6.7 34.7 5.9 24.7 55.8 48.1 58.5 11.6 12.7 13.2 21.2 41.3 16.3 46.7 19.9 68.7 43.1 19.6 38.2 21.1 15.8 10.7 26.1 20.6 28.8 21.0 7.9 10.9 13.1 9.9 13.4 0.0 0.6 1.1 1.7 0.0 1.4 0.3 2.3 1.5 1.1 2.3 3.8 1.3 0.1 4.6 0.1 0.5 2.4 0.8 19.3 16.9 15.8 22.8 16.8 20.2 23.9 21.4 18.6 17.5 20.4 15.6 21.2 9.6 22.9 6.8 4.7 10.6 14.1 12.8 11.4 71.9 65.9 54.7 36.4 34.3 20.8 25.8 77.2 65.4 3.7 206.0 29.4 23.2 13.3 51.7 32.5 20.8 46.0 4.4 7.2 47.8 65.3 17.6 47.4 60.0 1.3 26.1 15.0 148.4 16.3 151.4 7.6 80.2 24.4 4.7 4.6 6.0 17.7 5.2 10.6 8.4 2.4 45.7 1.0 6.6 5.8 50.4 78.5 18.8 1.2 23.2 72.3 30.2 25.9 54.3 6.6 17.3 24.5 1.6 9.0 24.3 10.5 79.8 4.2 44.3 75.3 18.2 NUF2 "CDCA1, CT106, NUF2R" ENSG00000143228 "NUF2 component of NDC80 kinetochore complex" Q9BZD4 1 163266576-163355764 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 28.4;lymphoid tissue: 26.0;testis: 53.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 60.8;Spermatocytes: 208.2;Spermatogonia: 40.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "T-reg: 4.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA059692, HPA076604" Supported Nucleoplasm,Kinetochore,Cytosol Yes Yes "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Kinetochore, Cytosol" "HPA059692: AB_2684103, HPA076604: " "unprognostic (9.41e-2)" "unprognostic (2.61e-1)" "unprognostic (2.56e-1)" "unprognostic (5.32e-3)" "unprognostic (6.20e-2)" "unprognostic (3.77e-2)" "prognostic unfavorable (1.04e-5)" "prognostic unfavorable (9.16e-4)" "prognostic unfavorable (4.83e-4)" "unprognostic (8.45e-2)" "prognostic unfavorable (9.75e-4)" "unprognostic (3.70e-2)" "unprognostic (0.00e+0)" "unprognostic (9.79e-2)" "unprognostic (7.88e-2)" "unprognostic (2.69e-1)" "unprognostic (5.96e-2)" 0.8 0.6 0.5 6.9 0.8 28.4 1.2 0.5 0.8 1.0 0.4 4.2 4.3 1.1 0.3 5.8 0.4 1.0 0.3 0.6 0.6 0.3 0.7 0.9 18.2 0.9 0.8 0.4 0.2 0.6 0.2 4.7 0.9 0.4 5.3 1.5 0.9 0.3 0.1 4.1 4.3 2.3 0.7 3.6 2.6 53.5 0.8 26.0 0.5 0.2 16.7 1.8 1.8 1.0 90.8 30.8 80.5 33.9 2.5 8.1 43.6 55.9 39.3 88.9 77.3 23.7 77.7 77.4 45.5 22.6 37.0 51.6 49.6 21.0 111.5 81.4 35.6 30.3 34.8 34.4 0.3 53.0 60.2 1.0 2.0 45.0 31.6 16.8 41.1 74.5 58.1 103.9 85.0 17.6 97.3 70.6 43.9 66.1 47.0 65.0 70.3 68.4 25.3 12.4 59.9 68.9 29.9 32.2 30.6 49.7 49.3 109.5 29.4 65.9 73.8 50.1 115.1 73.9 111.5 148.9 22.0 42.9 74.7 1.4 0.1 1.3 1.2 0.0 0.5 0.6 1.8 1.2 0.2 0.7 1.2 1.0 0.4 1.8 0.1 0.3 4.3 0.4 0.5 0.8 0.5 0.8 0.6 0.6 0.9 0.8 0.9 0.7 0.8 1.0 0.5 0.0 0.5 1.3 5.3 5.9 1.9 4.2 1.2 1.2 1.3 2.7 0.9 0.0 3.3 0.0 0.0 21.7 3.6 2.6 0.0 0.8 17.7 2.5 2.5 1.8 0.0 60.8 1.1 0.2 29.7 3.4 5.6 3.0 4.5 18.3 3.3 0.4 14.0 0.0 1.4 3.3 0.0 5.2 3.6 21.4 2.5 3.1 0.0 1.0 0.9 2.0 6.2 0.5 3.6 0.2 0.1 2.2 17.8 0.8 0.9 0.2 0.7 2.3 6.6 0.9 4.2 208.2 40.3 10.6 2.4 4.0 5.0 1.7 9.0 3.8 NUMA1 ENSG00000137497 "Nuclear mitotic apparatus protein 1" Q14980 11 72002864-72080693 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019841, HPA019859, HPA029912" Enhanced Supported Nucleoplasm,Cytosol NA Yes 62000 "Cluster 39: Non-specific - mRNA processing" "Cluster 89: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA019841: AB_1854708, HPA019859: AB_1854709, HPA029912: AB_10602811" "unprognostic (1.60e-2)" "unprognostic (3.31e-1)" "unprognostic (2.06e-2)" "unprognostic (2.84e-1)" "unprognostic (1.14e-1)" "unprognostic (6.47e-2)" "unprognostic (5.75e-2)" "unprognostic (8.74e-3)" "unprognostic (5.91e-2)" "unprognostic (9.45e-2)" "unprognostic (1.60e-2)" "unprognostic (2.51e-2)" "prognostic favorable (7.92e-4)" "unprognostic (1.28e-1)" "unprognostic (1.37e-1)" "unprognostic (1.49e-1)" "unprognostic (1.39e-1)" 55.2 59.9 27.8 51.1 45.6 69.6 67.1 37.4 40.5 75.4 36.2 77.7 59.6 111.2 43.3 67.9 82.7 62.7 47.6 24.0 33.0 49.9 29.8 65.4 57.9 40.4 34.3 112.3 68.8 98.6 42.1 60.8 41.9 111.4 54.5 46.2 78.1 85.6 82.5 93.8 61.9 86.7 28.4 56.8 59.0 42.4 36.0 79.3 73.9 54.8 53.2 75.2 65.9 83.4 64.4 80.0 97.2 66.4 85.1 88.2 48.8 85.0 97.2 86.4 74.6 83.9 115.5 86.7 72.0 104.0 61.6 134.2 89.7 85.8 78.0 89.9 43.1 105.8 130.4 64.1 69.1 81.1 74.0 94.0 55.7 84.1 84.3 133.0 74.0 76.7 63.4 101.1 59.4 124.2 105.6 45.2 61.2 122.3 57.6 127.9 170.0 67.6 64.2 98.6 117.3 166.6 134.9 123.5 123.6 42.3 166.4 47.1 103.0 90.6 69.9 130.1 56.9 64.8 69.7 120.0 61.1 38.0 53.0 3.7 4.1 1.9 6.4 2.3 4.7 3.4 4.0 5.0 3.5 5.8 4.9 3.6 2.8 5.0 4.4 8.2 5.2 6.0 27.8 45.6 37.4 40.5 24.0 33.0 40.4 34.3 41.9 28.4 36.0 83.4 52.4 41.7 41.3 42.7 36.6 25.9 30.1 25.3 74.0 60.7 62.3 63.4 5.7 34.3 32.2 53.3 73.0 25.5 42.6 56.3 17.6 27.9 31.9 55.5 48.5 44.9 47.4 43.3 27.5 32.1 13.4 41.9 57.6 92.8 31.0 84.7 37.9 23.6 28.7 52.2 34.0 68.3 32.6 32.1 24.9 17.8 69.0 36.3 19.6 33.7 26.8 51.8 53.5 27.6 58.9 30.9 31.2 50.8 40.8 29.6 57.0 26.9 35.4 59.8 39.5 64.3 36.9 14.8 21.4 51.9 28.1 45.0 44.8 44.2 52.2 26.0 NUP62 "DKFZp547L134, FLJ20822, FLJ43869, IBSN, MGC841, p62, SNDI" ENSG00000213024 "Nucleoporin 62" P37198 19 49906825-49929763 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Host-virus interaction, mRNA transport, Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 119.2;Late spermatids: 315.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005435, CAB020724" Supported Supported "Nucleoplasm,Nuclear membrane" NA Yes 31000 "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear membrane" Nucleoplasm "CAB020724: , HPA005435: AB_1079510" "unprognostic (2.26e-1)" "unprognostic (4.06e-2)" "unprognostic (9.92e-2)" "unprognostic (9.68e-2)" "unprognostic (7.83e-2)" "unprognostic (1.12e-2)" "prognostic unfavorable (2.50e-7)" "unprognostic (2.76e-2)" "unprognostic (3.61e-3)" "unprognostic (3.97e-2)" "unprognostic (4.06e-2)" "unprognostic (2.03e-2)" "prognostic unfavorable (5.71e-12)" "unprognostic (3.89e-3)" "unprognostic (3.62e-1)" "unprognostic (3.96e-1)" "unprognostic (3.27e-3)" 19.9 29.4 14.2 37.3 13.2 27.1 18.9 18.4 15.9 22.5 14.0 22.5 23.7 27.6 11.0 25.0 24.8 18.4 20.4 13.9 15.7 18.5 31.7 19.4 38.3 15.5 14.2 29.8 21.0 18.0 22.8 22.4 15.8 19.9 21.1 11.1 21.8 17.5 33.7 23.4 24.3 27.7 13.6 29.8 19.4 50.4 14.7 41.9 16.3 24.5 37.7 24.6 20.1 16.9 126.7 115.5 88.8 74.0 26.0 30.0 79.7 92.8 65.8 99.3 98.8 79.8 71.9 141.2 51.7 60.8 65.9 73.6 108.3 62.1 96.1 211.6 112.0 109.8 59.4 72.6 30.9 108.8 106.8 28.6 44.8 62.0 54.8 44.1 71.5 82.7 138.6 135.5 69.2 59.7 196.7 83.6 82.0 117.4 102.8 170.3 99.9 120.3 46.9 93.7 96.2 68.8 88.2 103.8 46.3 63.8 78.8 51.5 53.0 150.2 85.3 49.1 155.4 96.3 295.9 132.5 62.2 90.1 113.9 12.3 33.4 6.7 17.7 34.7 24.1 15.1 17.6 19.6 33.1 14.9 11.9 15.4 5.2 22.0 20.1 29.0 17.2 22.1 14.2 13.2 18.4 15.9 13.9 15.7 15.5 14.2 15.8 13.6 14.7 16.9 16.8 25.6 22.4 0.0 28.4 34.2 16.5 16.0 21.1 11.4 23.7 26.0 15.4 21.5 18.3 9.2 6.2 37.0 24.4 24.9 9.8 23.7 113.5 19.2 23.9 27.7 21.6 39.1 0.0 16.3 48.4 19.5 20.4 25.6 23.4 30.4 30.4 13.3 49.5 63.9 0.0 27.0 16.2 36.1 119.2 315.1 24.8 41.5 21.4 0.0 77.1 19.1 22.6 0.0 0.0 22.9 22.8 23.0 23.3 24.1 20.6 16.1 19.2 16.3 19.7 18.0 16.0 71.0 39.3 20.0 32.0 21.8 24.4 17.2 33.4 16.6 NUSAP1 "ANKT, BM037, FLJ13421, LNP, PRO0310p1, Q0310, SAPL" ENSG00000137804 "Nucleolar and spindle associated protein 1" Q9BXS6 15 41320794-41381050 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 88.6;lymphoid tissue: 101.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 266.7;Extravillous trophoblasts: 121.2;Granulosa cells: 93.3;Spermatocytes: 99.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "basophil: 10.7;T-reg: 7.7" "Group enriched" "Detected in many" 15 "granulocytes: 10.7;T-cells: 7.7" "Low cell line specificity" "Detected in many" "HPA042904, HPA074847" Supported Approved "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" Yes Yes "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli, Nucleoli fibrillar center" "HPA042904: AB_2678220, HPA074847: AB_2732269" "unprognostic (1.19e-1)" "unprognostic (9.53e-3)" "unprognostic (1.65e-1)" "unprognostic (8.78e-2)" "unprognostic (3.46e-2)" "unprognostic (2.97e-2)" "unprognostic (1.16e-3)" "unprognostic (1.74e-3)" "unprognostic (1.37e-2)" "unprognostic (4.14e-1)" "prognostic unfavorable (6.27e-4)" "unprognostic (8.49e-3)" "prognostic unfavorable (6.82e-14)" "unprognostic (4.76e-3)" "unprognostic (1.23e-1)" "unprognostic (2.18e-1)" "unprognostic (1.22e-1)" 1.8 14.1 0.2 7.8 0.2 88.6 1.5 0.3 0.4 3.6 0.3 6.1 7.0 1.1 0.1 17.7 1.1 1.0 1.1 0.2 0.2 2.6 5.0 3.8 28.7 0.3 0.4 4.4 1.3 0.0 0.6 6.5 0.3 1.1 8.0 0.1 3.6 0.6 5.4 9.4 7.4 2.7 0.2 7.8 4.5 10.9 0.3 101.5 0.9 0.1 31.5 1.9 6.4 0.3 146.0 38.3 165.1 64.6 3.5 5.9 37.0 107.4 74.6 138.9 130.6 58.4 67.0 63.5 42.5 44.4 99.1 107.6 104.2 46.2 132.4 98.5 62.3 149.6 102.0 50.7 0.2 67.3 57.2 0.9 1.3 69.1 37.3 21.7 72.0 104.2 70.1 237.5 105.7 30.7 147.5 82.2 59.8 139.8 55.0 136.5 156.5 67.5 42.4 29.3 85.7 55.2 129.8 88.5 25.7 46.0 106.2 76.1 33.7 89.9 104.8 101.5 206.2 81.3 145.8 200.5 42.1 163.6 171.2 10.7 0.1 0.5 0.1 0.0 0.0 0.3 0.5 0.5 0.3 0.6 0.0 0.3 0.2 0.4 0.0 0.3 7.7 0.5 0.2 0.2 0.3 0.4 0.2 0.2 0.3 0.4 0.3 0.2 0.3 0.3 1.9 0.0 1.5 1.3 14.2 38.5 10.3 21.2 31.9 0.9 9.9 13.7 1.1 17.2 5.0 0.0 0.0 72.2 13.4 14.4 3.9 2.3 33.2 10.7 11.6 7.3 3.0 266.7 1.4 0.5 121.2 14.6 25.5 21.8 7.0 93.3 10.8 3.9 36.7 0.0 1.5 15.5 24.4 13.8 22.7 14.6 0.3 17.5 3.6 1.9 6.1 1.9 4.1 1.0 1.3 1.5 0.4 1.9 57.2 5.3 2.6 5.4 1.1 1.0 0.0 2.8 12.1 99.6 59.9 69.5 24.9 19.3 22.9 38.8 30.0 10.3 NXPH2 NPH2 ENSG00000144227 "Neurexophilin 2" O95156 2 138669157-138780390 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.1;kidney: 4.1;ovary: 8.1" "Cell type enriched" "Detected in some" 6 "Inhibitory neurons: 156.1" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Group enriched" "Detected in many" 6 "medulla oblongata: 11.7;midbrain: 7.6;pons: 13.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 3.4;SiHa: 3.0;SuSa: 2.1;U-2 OS: 4.7;U-251 MG: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA034759 Approved "Secreted in brain" NA Yes "Cluster 73: Brain - Neuropeptide signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA034759: AB_10669732" "unprognostic (5.83e-2)" "unprognostic (8.83e-2)" "unprognostic (1.41e-1)" "unprognostic (2.72e-1)" "unprognostic (1.80e-1)" 0.2 0.0 1.8 0.1 1.7 0.0 0.1 1.0 1.8 0.1 0.2 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.0 1.0 0.4 4.1 0.0 0.0 0.0 11.7 7.6 8.1 0.0 0.0 0.1 0.1 13.1 0.0 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.9 0.6 3.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 4.7 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.7 1.0 1.8 1.0 0.4 11.7 7.6 13.1 1.9 1.1 1.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 156.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.5 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OIP5 "CT86, hMIS18beta, MIS18B" ENSG00000104147 "Opa interacting protein 5" O43482 15 41309273-41332591 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.3;skeletal muscle: 10.3;testis: 20.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 45.9;Extravillous trophoblasts: 24.0;Spermatocytes: 110.6;Spermatogonia: 56.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA052271, HPA059602" Enhanced Supported "Nuclear speckles,Vesicles" NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" Vesicles "HPA052271: AB_2681780, HPA059602: AB_2684079" "unprognostic (5.17e-2)" "unprognostic (7.26e-2)" "unprognostic (3.07e-1)" "unprognostic (1.59e-2)" "unprognostic (6.94e-2)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.79e-4)" "prognostic unfavorable (2.26e-4)" "unprognostic (2.71e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (9.34e-5)" "unprognostic (5.51e-2)" "unprognostic (0.00e+0)" "unprognostic (3.84e-2)" "unprognostic (2.02e-1)" "unprognostic (5.75e-2)" "unprognostic (2.86e-2)" 0.6 1.7 0.1 3.3 0.2 10.3 1.2 1.2 0.4 0.9 0.2 4.1 3.5 0.8 0.3 3.8 0.4 0.6 1.5 0.2 0.2 0.3 1.2 0.5 5.8 0.2 0.4 1.5 0.3 0.1 0.1 2.3 0.4 0.5 3.9 0.7 0.8 0.6 10.3 3.3 3.9 1.1 0.1 1.7 1.5 20.9 0.2 9.1 0.4 0.8 5.2 0.7 1.3 0.5 33.7 17.8 34.3 24.9 1.7 2.1 32.4 20.0 9.3 24.5 26.1 31.8 16.2 19.8 17.0 7.7 37.8 51.0 35.7 16.1 19.2 42.4 40.1 42.4 49.8 33.6 0.4 46.5 22.1 0.7 3.2 13.8 14.5 5.2 21.1 40.8 59.4 37.3 16.5 16.3 27.1 34.8 30.9 50.4 37.9 32.9 28.4 30.5 11.1 15.4 53.7 17.5 33.7 34.3 9.6 13.7 33.7 26.3 10.0 24.5 37.3 24.6 36.6 17.0 83.2 71.1 7.1 56.5 35.9 0.0 0.4 0.5 0.2 0.7 0.8 1.0 0.7 0.8 0.7 1.2 1.3 0.8 0.0 1.2 0.4 4.1 3.1 0.8 0.1 0.2 1.2 0.4 0.2 0.2 0.2 0.4 0.4 0.1 0.2 0.5 0.2 0.0 0.5 1.0 2.7 4.1 0.9 3.6 1.2 0.0 1.1 2.2 0.2 0.0 1.8 0.0 0.0 15.0 1.7 2.3 0.0 0.4 12.0 1.9 0.6 0.9 0.0 45.9 2.2 0.4 24.0 1.7 5.1 1.1 1.3 5.2 0.0 0.8 7.5 0.0 2.1 3.0 8.2 2.2 1.8 10.8 0.9 1.2 0.0 0.0 0.6 1.1 2.1 1.5 2.5 0.2 0.5 1.2 10.9 0.4 0.9 0.3 0.0 0.3 6.6 1.0 1.1 110.6 56.8 8.3 2.4 3.8 1.2 2.1 7.6 0.9 ORC1 "HSORC1, ORC1L, PARC1" ENSG00000085840 "Origin recognition complex subunit 1" Q13415 1 52372829-52404423 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 29.0;lymphoid tissue: 11.6" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 5.5;Early spermatids: 5.6;Erythroid cells: 14.1;Extravillous trophoblasts: 9.9;Plasma cells: 6.3;Spermatogonia: 6.5" "Cancer enhanced" "Detected in many" "testis cancer: 15.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "NK-cell: 3.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA027439, HPA027450" Approved Supported Nucleoplasm NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA027439: , HPA027450: AB_10602041" "unprognostic (3.28e-1)" "unprognostic (4.42e-3)" "prognostic favorable (1.74e-5)" "unprognostic (1.29e-2)" "unprognostic (7.29e-2)" "unprognostic (2.34e-3)" "prognostic unfavorable (3.22e-5)" "unprognostic (3.77e-3)" "prognostic unfavorable (3.69e-4)" "unprognostic (3.86e-2)" "unprognostic (2.70e-3)" "unprognostic (8.39e-2)" "unprognostic (1.25e-10)" "unprognostic (4.56e-3)" "unprognostic (1.05e-1)" "unprognostic (2.45e-1)" "unprognostic (1.57e-2)" 0.4 0.6 0.2 3.5 0.1 29.0 1.1 0.6 0.2 0.6 0.0 3.4 1.7 0.6 0.1 2.7 0.3 0.4 0.2 0.1 0.2 0.5 0.6 0.6 6.7 0.3 0.0 0.5 0.3 0.3 0.3 1.9 0.2 0.4 4.0 1.0 0.6 0.1 0.5 2.0 2.3 0.9 0.0 2.0 1.0 5.2 0.2 11.6 0.3 0.1 7.7 0.9 1.0 0.3 19.3 20.8 33.0 21.7 0.8 2.7 31.8 13.5 12.2 38.9 40.0 25.8 10.7 44.2 11.6 8.5 17.8 25.9 48.9 16.9 33.8 19.0 28.1 53.2 30.2 25.8 0.2 71.9 29.2 1.4 0.8 38.1 4.3 2.7 11.7 27.6 63.0 20.9 12.8 14.4 56.9 34.0 73.1 11.7 29.5 60.2 51.3 43.1 6.8 25.0 18.5 15.6 31.0 18.8 10.3 30.5 10.2 28.7 5.4 15.8 22.5 24.9 34.0 10.9 31.1 54.4 15.6 52.6 19.5 0.0 0.1 0.0 0.2 0.1 0.2 0.2 0.4 0.4 0.6 0.8 0.1 0.3 0.4 3.4 0.2 0.0 1.2 0.3 0.2 0.1 0.6 0.2 0.1 0.2 0.3 0.0 0.2 0.0 0.2 0.3 0.6 0.0 0.0 0.3 1.7 0.9 0.3 0.4 1.2 0.7 0.7 1.1 0.5 0.0 0.1 0.0 0.0 5.5 0.7 1.2 0.0 0.3 5.6 0.5 0.6 0.5 0.0 14.1 0.7 0.2 9.9 0.7 0.5 0.6 0.0 2.8 0.0 0.2 2.9 0.0 0.7 1.3 0.0 0.3 0.4 3.8 0.6 0.6 0.0 1.0 0.3 0.2 0.0 0.5 0.5 0.2 0.8 0.4 6.3 0.2 0.2 3.9 0.1 0.9 0.0 0.6 0.7 4.1 6.5 2.5 1.1 1.8 1.1 0.9 3.7 0.4 OSBPL3 "KIAA0704, ORP-3, ORP3, OSBP3" ENSG00000070882 "Oxysterol binding protein like 3" Q9H4L5 7 24796540-24981634 "Plasma proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 123.1;Excitatory neurons: 176.1;Inhibitory neurons: 272.2;Microglial cells: 94.6;Plasma cells: 91.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 113.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000691, HPA048401" Enhanced Supported Nucleoli,Cytosol NA Yes "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol Nucleoli "HPA000691: AB_1854814, HPA048401: AB_2680386" "unprognostic (3.57e-1)" "unprognostic (1.14e-1)" "unprognostic (6.11e-3)" "unprognostic (3.89e-2)" "unprognostic (1.14e-1)" "unprognostic (1.12e-1)" "unprognostic (1.57e-3)" "unprognostic (4.51e-2)" "unprognostic (2.26e-1)" "unprognostic (2.05e-2)" "prognostic unfavorable (7.88e-4)" "unprognostic (2.34e-1)" "unprognostic (7.95e-3)" "unprognostic (3.38e-2)" "unprognostic (1.39e-1)" "unprognostic (1.20e-2)" "unprognostic (2.06e-2)" 2.6 1.2 3.6 6.8 4.2 4.1 3.9 2.8 5.9 10.2 3.8 5.9 9.3 2.2 0.8 7.6 5.1 5.0 2.6 3.9 4.4 16.0 1.2 8.6 11.3 3.8 3.7 5.2 1.9 14.1 2.0 3.9 3.5 2.2 6.0 1.3 3.7 2.5 3.3 10.3 7.6 3.7 3.1 6.8 8.5 2.8 4.5 8.3 9.8 2.0 14.4 13.3 6.5 5.1 40.2 10.7 7.8 14.4 17.3 34.5 17.5 44.5 49.3 20.4 32.1 27.0 52.0 22.2 6.2 47.8 26.9 34.6 23.6 33.4 31.4 13.5 9.8 5.3 16.4 20.4 24.5 15.3 113.8 17.0 27.2 26.7 31.8 26.0 31.0 19.0 28.4 30.1 34.9 0.0 9.4 18.7 15.3 38.1 13.7 7.5 21.6 9.1 20.4 28.2 1.6 16.1 30.3 21.5 6.7 23.0 11.1 1.5 37.1 9.1 17.9 49.4 33.7 20.7 32.8 55.6 19.5 24.7 102.0 5.8 1.9 1.5 8.5 1.7 7.3 3.3 5.3 5.6 3.3 1.6 1.8 3.5 0.4 7.7 1.2 2.3 9.5 2.5 3.6 4.2 2.8 5.9 3.9 4.4 3.8 3.7 3.5 3.1 4.5 5.1 2.2 0.0 26.1 123.1 18.3 12.1 8.0 8.8 21.6 0.3 3.8 4.4 5.5 5.7 22.2 25.8 0.0 8.4 13.2 3.8 3.9 3.5 0.3 24.6 2.3 3.6 1.8 11.1 176.1 3.9 2.1 3.1 19.4 31.9 0.0 0.4 3.6 0.5 10.8 0.0 272.2 1.7 20.3 12.7 9.3 0.3 0.6 13.2 16.0 94.6 7.8 4.8 14.4 44.2 3.6 24.4 4.5 0.0 91.7 5.2 3.3 0.5 53.1 0.2 0.0 3.4 4.6 0.5 5.0 16.5 8.0 4.0 18.5 20.3 4.5 16.5 OSER1 "C20orf111, dJ1183I21.1, HSPC207, Osr1, Perit1" ENSG00000132823 "Oxidative stress responsive serine rich 1" Q9NX31 20 44195939-44210771 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 842.5;Late spermatids: 2257.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045125 Approved Approved "Nucleoli,Nucleoli rim,Nuclear speckles" NA Yes "Cluster 5: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoli, Nucleoli rim, Nuclear speckles" "HPA045125: AB_10961629" "unprognostic (2.77e-2)" "unprognostic (3.01e-2)" "unprognostic (3.22e-1)" "prognostic unfavorable (2.58e-5)" "unprognostic (1.18e-1)" "unprognostic (6.07e-2)" "unprognostic (8.44e-3)" "unprognostic (3.31e-1)" "unprognostic (1.14e-1)" "unprognostic (8.78e-2)" "unprognostic (8.01e-3)" "unprognostic (9.87e-2)" "unprognostic (3.96e-1)" "unprognostic (2.14e-1)" "unprognostic (2.45e-1)" "unprognostic (8.39e-2)" "unprognostic (1.06e-1)" 43.4 26.6 22.0 22.3 23.2 128.5 42.3 24.7 26.8 37.2 21.9 39.2 27.2 35.1 30.7 46.2 34.9 23.6 37.5 21.9 24.1 35.7 38.1 36.0 27.7 25.0 23.7 42.5 23.5 29.4 24.3 25.2 24.4 36.7 24.7 25.1 36.9 21.5 110.1 51.8 37.3 25.7 24.1 40.1 32.9 116.3 23.8 25.3 37.7 61.1 32.5 44.6 39.2 27.8 50.6 37.1 28.9 22.6 75.2 54.6 32.7 45.0 69.6 71.0 64.1 93.9 54.7 49.1 44.3 43.3 96.1 73.9 31.8 42.7 59.3 16.2 20.1 16.1 99.8 66.8 41.6 27.6 26.8 64.5 72.3 47.1 86.1 38.7 32.8 30.6 24.9 64.9 40.2 75.8 22.5 35.9 25.7 46.5 39.3 32.8 46.4 35.0 37.3 34.7 28.2 27.5 64.2 90.5 62.2 33.9 45.1 25.6 27.8 60.6 45.3 35.8 39.7 44.3 49.1 48.4 42.6 20.6 31.1 264.8 68.4 119.5 50.0 68.3 54.1 120.1 57.1 49.7 60.7 115.2 67.7 61.8 306.7 67.7 100.2 39.7 73.8 91.5 22.0 23.2 24.7 26.8 21.9 24.1 25.0 23.7 24.4 24.1 23.8 27.8 51.2 19.2 21.0 14.4 70.0 259.4 137.6 95.4 101.3 10.3 69.1 75.2 38.7 18.6 61.3 12.9 4.2 40.4 48.6 58.6 37.2 45.1 842.5 94.7 48.0 36.8 49.5 25.0 9.0 36.4 38.2 48.6 37.2 175.1 33.0 22.9 18.5 27.9 43.4 11.8 9.0 34.6 65.1 30.6 111.1 2257.1 40.7 55.2 76.5 5.6 84.2 31.0 30.9 5.0 12.5 49.3 87.7 35.3 40.6 91.4 68.1 33.5 36.9 14.8 19.7 47.0 45.6 194.8 71.7 50.4 198.5 173.6 55.2 22.3 47.5 119.4 PABPC1L "C20orf119, dJ1069P2.3, ePAB, PABPC1L1" ENSG00000101104 "Poly(A) binding protein cytoplasmic 1 like" Q4VXU2 20 44910060-44959035 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 24.6;Collecting duct cells: 20.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA066650 Approved "Nuclear bodies,Cytosol" NA Yes "Cluster 50: Neutrophils - Cellular senescence" "Cluster 18: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 52: Non-specific - Transcription" Cytosol "Nuclear bodies" "HPA066650: AB_2685698" "unprognostic (4.98e-2)" "unprognostic (2.78e-1)" "prognostic unfavorable (3.80e-4)" "unprognostic (1.73e-2)" "unprognostic (2.26e-1)" "unprognostic (2.24e-2)" "unprognostic (1.77e-3)" "unprognostic (4.92e-3)" "unprognostic (3.69e-2)" "unprognostic (2.44e-1)" "unprognostic (2.28e-3)" "unprognostic (7.96e-2)" "prognostic unfavorable (4.00e-15)" "unprognostic (1.01e-1)" "unprognostic (1.88e-1)" "unprognostic (8.63e-2)" "prognostic favorable (8.84e-4)" 2.1 2.3 1.7 2.0 1.8 4.1 2.9 1.1 2.1 4.0 2.5 1.7 0.8 1.5 3.4 2.1 3.4 1.4 1.3 1.7 1.8 6.1 5.9 2.9 3.3 1.4 1.8 6.6 6.1 0.5 6.1 0.6 1.4 5.2 0.6 0.4 2.5 0.9 0.5 2.1 2.9 0.6 1.3 4.4 2.8 1.9 2.5 3.0 7.9 0.1 1.9 1.9 1.9 1.7 2.0 3.4 1.9 4.1 0.4 2.6 8.9 3.7 0.3 1.4 0.4 8.4 3.4 2.2 7.3 0.2 1.2 4.7 0.5 1.3 0.9 1.9 4.0 1.9 8.1 7.2 2.1 1.6 0.5 0.5 6.4 1.2 1.5 1.1 0.0 3.1 3.0 2.2 0.3 8.0 2.8 4.9 1.2 3.0 7.6 3.7 0.6 2.2 0.7 2.6 2.0 3.0 1.6 5.7 6.7 1.8 9.7 1.8 0.2 5.2 5.7 3.4 1.6 5.4 8.8 1.8 1.7 0.8 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.7 1.8 1.1 2.1 1.7 1.8 1.4 1.8 1.4 1.3 2.5 1.7 1.3 6.4 24.6 11.8 7.0 1.9 3.3 3.3 6.2 0.5 7.6 9.9 1.5 7.2 15.6 20.2 0.0 6.7 4.7 2.8 0.0 3.3 0.6 9.5 6.8 1.5 4.2 1.7 5.3 0.5 4.4 4.2 12.8 11.1 3.8 10.3 0.4 5.7 3.0 0.0 2.3 3.0 2.0 0.8 1.6 0.6 1.8 3.3 0.0 1.9 2.3 1.4 3.1 11.1 3.2 1.8 2.4 1.9 5.1 3.5 1.5 1.5 10.1 1.3 0.0 2.1 2.6 0.9 2.1 4.9 1.7 3.8 7.0 2.1 4.4 2.9 PAFAH2 HSD-PLA2 ENSG00000158006 "Platelet activating factor acetylhydrolase 2" Q99487 1 25959767-25998117 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 48.7" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 52.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018157 Approved NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA018157: AB_1854928" "unprognostic (9.89e-2)" "unprognostic (2.60e-1)" "unprognostic (3.63e-3)" "prognostic favorable (3.28e-6)" "unprognostic (5.19e-2)" "unprognostic (2.12e-1)" "unprognostic (1.05e-1)" "unprognostic (1.78e-1)" "unprognostic (2.43e-1)" "unprognostic (1.04e-1)" "unprognostic (4.46e-2)" "unprognostic (2.62e-1)" "prognostic favorable (0.00e+0)" "unprognostic (8.15e-2)" "unprognostic (8.17e-2)" "unprognostic (1.59e-2)" "unprognostic (7.27e-2)" 4.6 7.3 4.7 6.5 6.5 6.8 9.2 6.3 6.0 8.8 6.7 16.3 17.4 4.9 9.9 7.8 8.3 10.4 9.7 4.5 5.8 19.3 18.3 8.6 8.4 6.4 6.5 4.7 31.2 22.9 5.9 9.2 6.5 8.8 16.6 14.1 10.0 6.3 18.0 11.4 19.0 6.9 5.5 7.6 15.6 7.7 6.5 48.7 16.4 10.7 7.4 7.0 5.5 8.2 8.6 10.7 6.7 7.6 13.9 10.9 13.7 9.6 5.0 8.6 5.7 4.4 18.1 3.8 11.7 5.7 8.1 7.5 10.1 9.3 11.0 7.8 6.1 6.3 4.6 8.8 8.4 3.3 52.5 7.2 21.2 13.2 8.7 4.7 8.3 8.9 8.9 7.1 11.7 3.8 10.3 3.3 13.4 29.9 5.9 8.4 6.3 8.7 13.9 3.0 8.0 6.8 5.7 7.7 18.2 11.0 12.7 6.0 7.8 5.9 7.4 12.5 7.7 13.0 18.1 4.8 12.5 13.2 20.0 36.2 6.7 60.2 23.7 6.4 15.3 3.5 8.3 15.4 5.0 4.4 10.6 14.9 5.8 17.4 2.4 39.0 9.0 8.7 4.7 6.5 6.3 6.0 4.5 5.8 6.4 6.5 6.5 5.5 6.5 8.2 4.6 16.0 12.8 9.8 3.2 1.5 2.1 5.3 1.8 9.5 9.4 4.8 6.8 11.5 11.9 18.4 27.1 11.2 37.7 34.9 3.9 11.1 1.1 8.6 4.5 5.6 7.8 3.2 4.0 7.3 9.5 3.5 12.2 13.2 27.8 7.3 5.7 21.4 11.2 5.0 3.6 18.2 4.1 11.6 1.6 1.0 2.5 7.1 8.8 5.6 7.3 6.3 23.7 4.0 10.0 10.6 15.8 2.6 6.5 4.2 43.1 18.3 8.9 8.8 6.6 5.3 4.1 19.9 8.9 4.5 3.8 10.0 9.0 4.4 19.4 4.9 PAK4 ENSG00000130669 "P21 (RAC1) activated kinase 4" O96013 19 39125770-39182816 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "A549: 154.7;MCF7: 172.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025747, CAB044670, HPA070175, HPA072220" Uncertain Supported "Plasma membrane,Cell Junctions" NA Yes "Cluster 26: Non-specific - Mitochondria" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Plasma membrane, Cell Junctions" "CAB025747: , CAB044670: AB_1854940, HPA070175: AB_2686232, HPA072220: AB_2686497" "unprognostic (1.71e-1)" "unprognostic (2.84e-1)" "unprognostic (5.86e-2)" "unprognostic (2.84e-2)" "unprognostic (1.93e-1)" "unprognostic (8.51e-2)" "unprognostic (3.56e-3)" "unprognostic (1.13e-3)" "unprognostic (3.90e-2)" "unprognostic (4.04e-2)" "unprognostic (7.29e-2)" "prognostic unfavorable (9.85e-4)" "prognostic favorable (5.29e-5)" "unprognostic (2.39e-1)" "unprognostic (7.05e-2)" "unprognostic (2.02e-1)" "unprognostic (4.85e-2)" 11.6 20.0 16.7 8.1 18.2 5.3 22.1 14.2 18.4 27.2 14.0 30.2 27.4 20.6 9.4 43.9 23.4 7.5 15.5 13.9 13.4 37.2 26.2 39.6 4.5 17.1 17.2 24.2 31.8 16.2 30.5 16.3 15.8 40.7 8.0 5.8 42.4 11.0 14.0 40.4 25.1 5.7 12.0 13.8 25.3 35.0 15.7 5.4 29.3 4.3 5.4 20.2 30.4 17.0 62.8 154.7 22.7 34.8 7.1 7.5 68.1 29.3 11.7 19.3 19.4 102.1 51.9 14.3 43.3 18.7 25.2 22.7 12.6 23.2 7.2 38.0 35.4 16.9 27.5 50.4 11.3 17.5 23.6 9.0 10.2 18.1 12.9 12.6 25.5 21.4 34.3 11.0 11.8 172.7 18.6 18.9 41.4 55.2 36.7 18.5 17.9 10.9 19.0 67.9 72.2 49.9 29.8 130.6 33.6 11.7 58.1 28.4 42.8 32.6 55.6 37.8 53.0 12.3 12.9 11.9 39.9 10.3 39.9 0.3 0.7 1.2 0.6 0.3 0.8 0.5 0.7 1.1 0.9 0.6 0.5 0.5 0.5 0.9 0.6 0.8 0.9 0.7 16.7 18.2 14.2 18.4 13.9 13.4 17.1 17.2 15.8 12.0 15.7 17.0 5.1 0.0 1.5 9.4 3.9 14.4 15.9 13.8 9.6 18.8 34.2 21.7 2.0 20.0 9.1 18.4 25.0 42.6 4.4 47.5 31.3 20.5 4.1 19.5 8.5 15.0 44.9 5.0 3.9 19.7 67.4 8.8 23.9 23.3 5.7 21.6 10.0 13.3 9.6 21.9 4.2 33.8 28.5 5.3 4.1 6.4 11.8 3.6 7.2 8.4 11.2 13.6 8.2 9.5 13.5 21.8 44.2 10.5 5.8 21.7 39.5 14.4 13.7 13.4 0.0 8.5 7.5 10.4 24.0 20.1 18.8 65.4 6.0 22.3 33.9 24.3 PAQR4 FLJ30002 ENSG00000162073 "Progestin and adipoQ receptor family member 4" Q8N4S7 16 2969270-2973484 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 124.5;retina: 63.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 58.4;Oligodendrocytes: 62.0;Rod photoreceptor cells: 153.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "non-classical monocyte: 3.6" "Lineage enriched" "Detected in single" 9 "monocytes: 3.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA068394 Approved Vesicles NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 25: RPMI-8226 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Vesicles "HPA068394: AB_2685980" "unprognostic (1.93e-1)" "unprognostic (2.75e-1)" "unprognostic (6.73e-2)" "unprognostic (1.30e-3)" "unprognostic (8.39e-2)" "unprognostic (3.00e-2)" "prognostic unfavorable (6.86e-4)" "unprognostic (2.62e-2)" "unprognostic (7.59e-2)" "unprognostic (9.65e-3)" "unprognostic (5.21e-2)" "unprognostic (8.59e-2)" "prognostic unfavorable (3.01e-6)" "prognostic favorable (1.70e-4)" "unprognostic (1.36e-1)" "unprognostic (3.79e-2)" "unprognostic (6.06e-3)" 4.3 8.1 54.4 6.9 80.8 15.7 4.3 80.0 65.3 3.6 32.7 6.5 6.2 2.3 0.5 11.3 3.7 6.9 9.3 55.1 56.4 3.9 3.4 7.9 8.7 93.0 77.4 0.7 11.9 38.4 2.1 2.6 85.9 11.8 5.6 63.7 22.7 1.4 17.6 16.1 6.3 3.5 68.1 7.9 10.5 3.2 74.6 11.0 3.3 27.9 10.3 2.5 4.6 124.5 36.9 30.9 34.4 49.5 5.6 10.0 11.3 13.9 16.6 24.9 23.5 18.8 38.3 36.8 18.3 16.1 17.5 50.8 36.1 21.7 10.4 38.8 16.3 11.5 63.6 25.4 0.6 24.1 39.2 2.4 11.3 13.5 3.5 12.6 16.7 30.7 22.5 95.6 21.7 73.8 35.1 25.8 29.1 55.3 21.6 69.5 45.0 117.6 17.5 12.4 77.3 36.0 51.2 48.5 37.3 4.6 51.6 37.2 10.3 43.0 26.3 20.0 19.8 42.2 30.7 49.3 19.1 32.4 48.4 0.0 0.4 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 3.6 0.2 0.0 0.3 54.4 80.8 80.0 65.3 55.1 56.4 93.0 77.4 85.9 68.1 74.6 124.5 4.8 0.0 0.0 13.4 2.0 3.1 1.6 2.6 2.2 14.9 5.2 5.2 1.1 12.8 7.8 0.0 58.4 2.2 2.0 5.1 0.0 5.2 0.8 3.0 1.5 4.5 4.2 12.6 8.9 11.3 8.9 2.0 2.6 5.2 2.5 4.6 3.9 0.3 13.3 6.7 4.5 5.5 6.1 7.6 4.6 3.6 0.6 7.2 5.4 2.8 2.2 27.8 2.1 4.5 62.0 9.5 2.5 0.0 5.5 5.0 2.2 1.0 11.0 153.4 0.0 0.3 3.5 1.5 6.3 4.1 5.1 0.5 1.8 1.0 10.9 1.0 PARP2 "ADPRTL2, ARTD2" ENSG00000129484 "Poly(ADP-ribose) polymerase 2" Q9UGN5 14 20343615-20357904 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Glycosyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052003 Approved Supported Nucleoplasm,Nucleoli NA Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Nucleoli "HPA052003: AB_2681689" "unprognostic (3.93e-1)" "unprognostic (7.92e-2)" "unprognostic (4.12e-1)" "unprognostic (1.24e-1)" "unprognostic (3.40e-2)" "unprognostic (7.30e-2)" "prognostic unfavorable (6.48e-4)" "unprognostic (1.97e-2)" "unprognostic (4.43e-2)" "unprognostic (9.35e-3)" "unprognostic (1.44e-2)" "unprognostic (1.42e-2)" "unprognostic (3.37e-3)" "unprognostic (2.83e-1)" "unprognostic (9.19e-2)" "unprognostic (1.91e-1)" "unprognostic (2.89e-2)" 17.7 21.1 21.1 10.7 22.0 26.8 17.5 21.4 31.4 18.1 16.4 19.3 12.8 20.9 17.8 14.6 17.5 10.0 17.1 22.5 21.0 15.5 17.2 13.5 14.5 19.5 18.9 22.9 17.9 11.1 21.0 12.9 19.8 13.9 14.0 26.4 14.2 13.4 32.4 19.2 14.2 15.8 19.0 16.5 16.3 23.8 19.8 11.9 16.7 27.1 17.9 13.8 15.3 22.1 55.5 39.5 59.7 45.3 19.4 18.4 43.4 60.2 32.5 74.8 91.8 36.8 51.3 40.4 26.5 19.0 64.8 50.1 78.3 27.5 87.8 32.4 38.3 37.2 46.6 63.3 17.3 77.9 20.4 12.5 23.0 45.5 51.1 20.5 38.5 48.0 39.2 53.4 52.3 33.5 40.1 33.0 33.0 62.8 60.0 49.7 79.7 26.5 30.0 28.2 41.3 28.3 65.3 36.8 17.9 37.4 34.2 25.8 26.6 45.3 68.1 31.5 48.1 49.3 67.7 53.4 19.0 33.3 51.4 1.9 5.0 0.5 8.9 4.8 11.7 6.8 8.4 7.9 5.5 4.1 9.0 8.6 0.1 7.6 2.6 5.6 5.3 4.8 21.1 22.0 21.4 31.4 22.5 21.0 19.5 18.9 19.8 19.0 19.8 22.1 12.1 25.6 6.5 7.2 9.5 6.5 10.5 16.1 18.8 29.2 7.4 10.0 14.0 5.7 19.9 7.3 12.5 25.8 10.2 4.5 7.9 12.8 9.3 9.9 13.3 11.0 4.8 30.3 17.6 8.7 22.2 11.6 7.7 11.3 8.2 18.4 6.8 10.1 11.9 30.3 15.5 5.0 14.2 4.6 5.1 9.8 11.5 6.6 8.8 9.4 4.2 20.7 6.2 6.0 9.3 10.1 4.5 17.0 19.1 4.5 5.3 7.4 28.0 23.2 6.6 9.8 18.5 20.9 41.5 11.3 4.8 14.9 6.2 16.7 7.4 7.0 PASK "KIAA0135, PASKIN, STK37" ENSG00000115687 "PAS domain containing serine/threonine kinase" Q96RG2 2 241106099-241150264 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.8;lymphoid tissue: 22.9" "Cell type enhanced" "Detected in many" "Peritubular cells: 24.5;Theca cells: 26.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 19.8" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA016450, HPA021079" Uncertain Supported Cytosol NA Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 14: REH - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA016450: AB_1854992, HPA021079: AB_1854993" "unprognostic (1.76e-2)" "unprognostic (1.29e-2)" "unprognostic (2.84e-1)" "unprognostic (1.41e-2)" "unprognostic (1.14e-1)" "unprognostic (8.99e-6)" "unprognostic (1.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.60e-3)" "unprognostic (1.58e-2)" "unprognostic (1.02e-2)" "unprognostic (6.35e-2)" "unprognostic (7.12e-2)" "unprognostic (1.52e-3)" "unprognostic (1.68e-1)" "unprognostic (6.44e-2)" "unprognostic (4.38e-3)" 1.6 1.1 3.7 7.1 19.8 8.8 2.1 1.0 5.3 2.5 3.1 2.4 3.4 2.1 3.9 3.3 6.1 2.0 1.1 2.7 1.7 3.7 1.4 3.2 13.7 1.9 1.9 1.9 3.6 2.4 4.6 1.0 1.8 10.0 2.3 11.9 2.9 1.4 0.8 4.1 4.5 1.2 0.3 4.1 3.0 16.1 3.2 22.9 5.1 0.2 7.8 2.1 2.2 5.2 7.4 9.9 12.9 16.7 1.1 1.9 17.4 7.0 2.2 6.3 8.8 8.1 7.4 3.8 1.4 1.5 13.8 17.9 15.1 6.1 4.6 15.6 13.8 10.6 19.1 14.4 0.8 14.7 16.0 0.9 4.7 6.5 1.9 2.6 4.6 16.2 14.0 5.2 4.5 8.0 17.5 15.4 14.6 8.8 5.9 27.5 13.3 4.7 2.5 16.0 23.1 7.0 3.9 8.0 3.2 6.8 6.7 10.5 6.1 8.8 7.7 11.1 9.6 6.8 7.4 18.1 5.4 10.9 8.2 4.4 0.6 0.5 1.0 0.4 0.9 4.5 3.9 3.5 0.8 3.9 2.3 2.6 0.8 1.9 0.7 0.4 4.1 2.2 3.7 19.8 1.0 5.3 2.7 1.7 1.9 1.9 1.8 0.3 3.2 5.2 2.3 3.2 7.9 2.6 8.5 2.7 1.2 1.6 2.2 2.6 3.5 4.3 3.1 2.8 1.9 3.7 4.2 0.9 2.2 3.1 0.0 1.5 14.9 13.9 1.6 8.5 0.0 13.3 12.5 2.0 1.7 2.7 3.6 4.4 3.8 11.7 17.5 1.5 2.0 1.7 6.1 3.5 0.0 4.7 2.0 3.5 5.9 2.1 12.4 3.7 2.7 2.1 7.2 0.5 2.6 0.9 1.0 24.5 4.7 1.7 1.9 1.4 12.3 18.7 0.0 2.1 2.1 16.1 12.7 2.6 1.4 0.3 19.1 26.5 3.9 0.9 PBK "CT84, FLJ14385, Nori-3, SPK, TOPK" ENSG00000168078 "PDZ binding kinase" Q96KB5 8 27809624-27838082 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 22.8;testis: 70.3" "Group enriched" "Detected in many" 5 "Early spermatids: 364.9;Spermatocytes: 436.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 282.8" "Group enriched" "Detected in many" 4 "basal ganglia: 4.7;white matter: 13.9" "Not detected" "Not detected" "HPA005753, HPA050656" Enhanced Supported Approved Cytosol NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA005753: AB_1855018, HPA050656: AB_2681205" "unprognostic (7.17e-2)" "unprognostic (7.21e-3)" "unprognostic (1.04e-3)" "unprognostic (2.77e-2)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (8.29e-5)" "unprognostic (3.65e-3)" "unprognostic (7.38e-2)" "unprognostic (2.88e-3)" "prognostic unfavorable (6.56e-4)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.18e-12)" "unprognostic (9.61e-2)" "unprognostic (1.86e-1)" "unprognostic (8.30e-2)" "unprognostic (8.68e-2)" 1.1 0.6 0.1 6.6 0.1 9.1 2.3 0.0 0.1 1.1 0.0 8.9 8.4 1.2 0.0 6.6 0.6 0.7 0.2 0.1 0.1 0.4 1.1 0.7 12.8 0.1 0.3 0.2 0.4 0.2 0.0 5.1 0.2 0.4 10.1 0.0 0.9 0.0 0.2 4.8 8.1 2.7 0.1 1.5 3.6 70.3 0.3 22.8 0.5 0.1 12.4 1.6 2.1 0.1 282.8 94.2 94.4 57.9 8.3 15.7 36.9 129.5 63.0 133.2 112.3 33.7 51.2 156.4 43.3 51.7 150.2 76.4 87.6 44.7 145.7 35.8 48.0 35.0 64.6 49.2 0.6 25.7 54.1 4.4 36.0 62.6 32.8 24.3 68.5 75.9 54.3 100.6 160.4 34.5 87.7 29.1 15.6 80.1 80.0 54.4 126.9 41.2 51.2 44.9 36.1 53.2 48.2 56.0 75.0 26.2 58.0 37.3 40.6 85.6 207.3 111.5 141.5 15.4 39.4 70.1 54.0 43.4 188.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.3 0.2 0.1 0.3 0.1 0.2 0.0 0.0 0.0 4.2 8.9 2.8 10.8 0.0 0.0 2.9 2.4 0.5 2.8 2.6 0.0 0.0 29.8 1.3 5.5 0.0 0.6 364.9 2.5 2.2 2.4 0.0 61.7 0.1 0.0 49.3 6.7 6.6 3.5 0.0 13.5 5.7 1.7 5.0 0.0 0.1 9.4 6.1 1.9 1.6 76.8 8.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 3.0 14.0 2.0 1.5 0.3 0.1 0.0 6.6 0.1 5.8 436.4 38.1 9.4 2.4 6.7 1.9 2.4 18.7 3.8 PCID2 FLJ11305 ENSG00000126226 "PCI domain containing 2" Q5JVF3 13 113177536-113208715 "Predicted intracellular proteins" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 204.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069107, HPA073074" Uncertain Approved Nucleoplasm,Nucleoli NA Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nucleoli" "HPA069107: AB_2686088, HPA073074: AB_2686568" "unprognostic (2.53e-2)" "unprognostic (2.94e-2)" "unprognostic (4.02e-1)" "unprognostic (1.26e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (7.80e-5)" "unprognostic (1.73e-3)" "unprognostic (1.50e-1)" "unprognostic (1.89e-1)" "unprognostic (1.47e-1)" "unprognostic (3.02e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (4.24e-6)" "unprognostic (1.41e-2)" "unprognostic (5.41e-3)" "unprognostic (1.45e-1)" "unprognostic (6.28e-2)" 22.2 29.0 16.6 15.8 17.4 15.5 22.9 19.0 18.8 27.0 18.3 25.2 12.1 23.0 23.0 19.3 25.9 17.1 37.7 16.8 17.3 20.1 23.8 18.6 25.8 16.4 16.6 33.7 23.9 19.1 22.6 15.5 16.4 24.7 18.5 10.7 23.8 19.2 29.1 18.9 20.2 21.8 16.5 24.7 24.4 45.3 17.6 24.4 20.8 24.4 23.0 23.9 22.4 18.8 62.9 26.3 39.1 34.7 70.2 52.3 27.4 47.2 70.7 64.4 59.1 51.9 57.7 50.2 30.7 64.5 81.6 38.8 62.9 42.8 71.2 44.3 62.1 64.8 68.1 45.9 70.0 110.4 25.5 43.3 46.6 40.4 71.1 51.4 51.3 68.5 50.4 19.9 73.6 30.3 59.4 77.9 38.9 115.1 33.2 53.4 43.4 48.0 58.8 31.3 52.0 31.9 29.5 72.2 55.9 39.3 39.9 133.4 33.5 19.0 68.7 27.9 36.2 30.4 30.4 70.4 65.3 74.1 44.2 28.2 25.5 20.0 68.9 34.4 81.6 39.7 58.0 72.5 26.0 39.5 52.2 54.6 3.9 22.6 33.2 24.8 64.7 54.7 16.6 17.4 19.0 18.8 16.8 17.3 16.4 16.6 16.4 16.5 17.6 18.8 26.5 19.2 16.7 16.3 28.4 21.5 29.1 37.8 17.6 23.6 25.5 32.3 27.8 21.5 23.7 14.7 16.7 30.2 38.5 7.8 27.4 22.8 52.8 26.8 35.7 26.2 7.8 32.8 43.6 13.8 24.7 33.8 18.8 21.7 10.8 39.0 18.9 18.4 20.2 37.0 33.7 15.6 16.2 18.2 14.0 18.1 41.3 17.2 16.0 26.2 24.0 19.0 38.1 25.1 40.4 18.1 15.8 40.6 16.8 46.3 13.6 23.6 30.4 23.8 19.7 37.4 30.9 204.4 72.7 17.6 24.7 31.1 43.7 33.0 20.1 25.3 PCLAF "KIAA0101, NS5ATP9, OEATC-1, p15(PAF), PAF15" ENSG00000166803 "PCNA clamp associated factor" Q15004 15 64364304-64387687 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 128.6;lymphoid tissue: 73.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 82.2;Extravillous trophoblasts: 160.2;Granulosa cells: 48.8;Hofbauer cells: 110.2;Syncytiotrophoblasts: 42.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 4 "T-reg: 23.6" "Lineage enriched" "Detected in many" 4 "T-cells: 23.6" "Low cell line specificity" "Detected in all" HPA047929 Supported Centrosome NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "HPA047929: AB_2680215" "unprognostic (5.34e-2)" "unprognostic (1.36e-3)" "unprognostic (9.39e-2)" "unprognostic (1.28e-1)" "unprognostic (4.16e-1)" "unprognostic (2.22e-1)" "prognostic unfavorable (3.26e-5)" "unprognostic (4.38e-3)" "unprognostic (1.91e-3)" "unprognostic (7.26e-2)" "unprognostic (2.56e-3)" "unprognostic (9.65e-2)" "prognostic unfavorable (9.77e-15)" "unprognostic (5.59e-2)" "unprognostic (2.05e-1)" "unprognostic (8.65e-2)" "unprognostic (3.22e-1)" 2.1 1.4 0.9 22.9 1.0 128.6 3.9 1.4 1.1 1.7 0.8 19.0 14.7 4.5 1.2 15.2 1.3 2.5 0.4 0.9 0.6 1.2 3.6 2.5 49.5 1.0 0.8 0.4 1.9 0.8 0.5 8.7 0.9 2.0 22.6 0.3 2.3 0.3 0.4 6.7 15.8 5.0 0.5 7.4 8.1 1.1 1.0 73.8 2.2 0.1 47.1 7.9 4.9 1.9 212.6 165.8 154.4 140.8 15.9 60.9 134.4 146.2 84.8 185.4 276.4 198.4 202.1 343.7 46.4 57.4 64.8 153.6 340.7 83.1 235.3 192.5 124.8 352.5 202.5 209.8 1.5 285.3 153.8 20.0 7.9 156.4 31.9 52.3 168.9 175.9 201.3 104.4 248.1 187.8 268.0 605.5 73.9 179.9 73.4 416.6 353.8 247.1 115.9 200.2 19.1 86.7 112.8 105.2 69.3 78.9 153.8 365.3 36.3 158.4 308.6 177.8 386.7 65.5 223.4 229.0 67.7 512.9 108.5 2.4 0.3 0.9 1.4 0.2 0.2 2.0 4.4 4.2 2.8 0.6 0.5 1.0 2.7 5.7 0.4 0.3 23.6 2.3 0.9 1.0 1.4 1.1 0.9 0.6 1.0 0.8 0.9 0.5 1.0 1.9 0.5 9.6 11.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 27.5 25.5 0.0 0.0 5.0 1.8 0.0 82.2 8.3 0.0 1.9 6.5 0.0 18.6 10.4 8.5 0.0 0.0 0.0 3.0 160.2 25.4 0.0 13.8 3.8 48.8 0.0 0.0 110.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 4.3 0.0 0.0 3.0 3.6 0.0 0.0 0.0 20.6 0.0 0.0 0.0 0.0 42.1 5.8 7.6 0.0 0.0 PCNA ENSG00000132646 "Proliferating cell nuclear antigen" P12004 20 5114953-5126626 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Host-virus interaction" DNA-binding "Cancer-related genes, Deafness, Disease variant, Dwarfism, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 383.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000148, HPA030521, HPA030522, HPA030523" Enhanced Enhanced Nucleoplasm No Yes 170000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB000148: AB_628110, HPA030521: AB_10600218, HPA030522: AB_10602096, HPA030523: AB_10602199" "unprognostic (5.21e-2)" "prognostic favorable (1.86e-5)" "unprognostic (2.96e-2)" "unprognostic (2.43e-1)" "unprognostic (3.17e-1)" "unprognostic (5.60e-3)" "prognostic unfavorable (2.61e-4)" "unprognostic (1.47e-2)" "unprognostic (2.22e-1)" "unprognostic (3.89e-2)" "unprognostic (1.01e-2)" "unprognostic (9.78e-2)" "prognostic unfavorable (3.03e-6)" "unprognostic (2.12e-2)" "unprognostic (2.29e-1)" "unprognostic (7.11e-3)" "unprognostic (7.46e-2)" 31.2 47.2 23.2 85.2 26.0 383.2 51.0 26.8 29.7 41.5 26.8 89.0 70.7 38.1 30.9 81.2 39.1 34.8 30.6 23.0 24.4 43.7 55.3 37.5 168.8 25.1 24.0 37.7 32.8 42.4 25.1 69.8 26.0 32.2 93.7 94.1 40.3 38.3 27.9 62.8 72.9 47.9 26.8 54.0 53.9 62.3 23.3 219.9 42.0 26.8 137.3 51.0 42.3 30.0 769.1 591.4 585.0 253.7 136.1 126.6 409.5 491.6 288.3 453.7 640.0 465.3 594.2 773.4 155.7 177.5 395.2 558.8 350.7 594.4 413.2 231.7 386.8 543.7 207.8 1098.3 57.8 753.7 233.0 92.6 138.2 387.2 91.7 95.3 263.3 503.6 493.9 631.2 449.7 278.3 1450.6 829.3 439.9 592.0 322.9 787.9 514.1 622.5 208.5 441.1 500.8 339.4 345.1 524.6 351.9 213.9 371.2 378.0 177.2 324.3 373.3 461.5 572.0 317.2 981.6 1313.9 145.9 707.4 426.2 5.0 23.2 18.5 36.5 23.3 45.7 33.5 45.7 37.1 32.6 29.2 41.6 37.3 7.7 43.6 24.7 29.9 48.1 36.7 23.2 26.0 26.8 29.7 23.0 24.4 25.1 24.0 26.0 26.8 23.3 30.0 32.4 44.8 26.0 2.9 40.6 67.7 44.4 121.4 44.3 42.1 27.5 45.2 14.5 21.5 60.5 58.8 27.1 171.5 44.3 42.9 60.7 51.6 176.0 30.2 21.4 34.8 19.9 189.0 4.3 39.6 175.6 38.7 21.9 27.7 22.7 53.1 29.6 27.1 96.7 32.0 5.9 53.9 75.3 24.2 33.4 109.1 36.1 32.7 37.4 3.7 47.6 74.0 23.7 4.0 13.5 28.3 20.3 40.3 56.6 23.3 33.3 46.1 44.1 97.1 52.6 29.2 46.1 149.1 101.1 65.5 49.7 66.4 48.6 29.6 84.5 40.4 PES1 "NOP7, PES" ENSG00000100029 "Pescadillo ribosomal biogenesis factor 1" O00541 22 30576625-30607083 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040210, HPA062439, HPA066670" Supported Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA040210: AB_2676885, HPA062439: AB_2684764, HPA066670: AB_2685700" "unprognostic (1.82e-1)" "unprognostic (5.88e-2)" "unprognostic (5.59e-3)" "unprognostic (4.83e-2)" "unprognostic (1.48e-1)" "unprognostic (3.23e-3)" "prognostic unfavorable (1.84e-9)" "unprognostic (3.29e-2)" "unprognostic (3.40e-1)" "unprognostic (1.73e-1)" "unprognostic (4.79e-2)" "unprognostic (2.46e-2)" "unprognostic (5.65e-2)" "unprognostic (1.27e-3)" "unprognostic (1.65e-1)" "unprognostic (4.56e-2)" "unprognostic (1.42e-1)" 33.3 41.0 26.3 29.2 28.6 35.5 32.2 26.7 30.5 31.8 27.1 29.6 21.7 35.5 21.2 43.6 29.4 20.2 28.8 26.9 26.2 38.7 48.2 26.2 32.3 27.1 27.2 34.2 57.3 30.1 21.8 21.5 27.6 32.9 19.6 9.2 29.3 21.5 48.8 45.3 28.2 22.5 25.8 34.4 35.7 40.0 27.0 23.8 27.1 20.0 27.3 35.0 31.9 30.0 132.2 146.6 53.0 113.7 59.9 58.4 81.6 84.7 69.6 141.6 110.0 170.6 55.2 177.2 74.4 97.0 110.3 89.4 163.9 153.5 103.1 76.4 159.8 85.9 80.8 149.0 149.3 209.6 86.8 82.7 94.7 148.3 147.3 68.3 93.0 62.4 144.6 69.9 87.7 164.3 102.6 209.8 103.1 128.3 106.7 129.0 91.7 173.3 78.9 88.7 91.4 94.6 84.2 94.6 117.8 42.0 66.8 106.1 74.2 165.9 126.1 85.3 145.1 88.1 81.0 178.6 116.2 94.9 109.0 7.5 24.9 6.4 18.9 29.8 23.2 20.2 17.4 18.1 26.8 20.0 19.4 18.0 0.9 20.0 22.3 23.2 14.3 29.3 26.3 28.6 26.7 30.5 26.9 26.2 27.1 27.2 27.6 25.8 27.0 30.0 23.6 3.2 18.9 4.9 17.4 22.6 23.4 32.7 22.2 6.5 14.1 12.2 3.8 24.3 22.1 25.8 8.4 34.9 7.8 19.6 25.4 48.0 44.4 11.7 13.8 23.2 23.4 24.6 4.3 43.9 40.0 15.4 22.4 10.6 18.3 24.4 27.8 22.8 38.4 3.3 4.3 22.4 22.4 27.8 12.6 14.3 19.9 21.2 21.4 2.8 29.0 13.5 16.5 6.6 5.1 38.7 16.2 20.3 28.3 26.4 31.3 55.1 24.6 8.9 19.7 23.2 20.7 28.7 20.9 25.9 22.9 28.5 13.5 19.9 29.7 15.1 PGAP4 "C9orf125, MGC12992, TMEM246" ENSG00000165152 "Post-GPI attachment to proteins GalNAc transferase 4" Q9BRR3 9 101473170-101533537 "Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 16 "Cardiomyocytes: 52.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 25.5;hTERT-RPE1: 28.8;OE19: 48.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011318, HPA054041" Uncertain Approved Mitochondria NA Yes "Cluster 45: Intestine - Brush border" "Cluster 21: OE19 - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA011318: AB_2668482, HPA054041: AB_2682353" "unprognostic (2.58e-2)" "unprognostic (4.76e-2)" "unprognostic (5.52e-1)" "unprognostic (2.81e-3)" "unprognostic (2.72e-2)" "unprognostic (9.15e-2)" "unprognostic (1.20e-3)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "unprognostic (4.24e-1)" "unprognostic (3.51e-2)" "unprognostic (2.09e-1)" "prognostic favorable (1.55e-8)" "unprognostic (1.62e-1)" "unprognostic (1.91e-1)" "unprognostic (2.50e-1)" "unprognostic (9.16e-2)" 3.9 10.3 21.5 2.2 21.3 0.5 2.4 18.9 26.2 16.6 4.5 13.4 8.4 7.1 3.7 14.4 13.7 6.8 30.4 24.9 26.1 4.7 2.4 5.4 0.4 17.9 13.4 19.5 11.1 16.6 12.3 0.6 26.1 6.9 11.2 9.9 6.1 9.4 4.8 12.0 7.6 6.7 9.6 1.6 16.0 2.8 19.2 0.9 4.2 6.1 2.4 6.4 11.9 20.3 0.0 14.6 11.3 0.0 0.3 0.2 0.0 9.8 14.1 7.0 13.8 0.7 7.8 0.0 3.2 17.9 0.8 23.1 0.0 16.1 4.2 0.0 5.8 8.1 10.3 0.0 0.5 0.0 0.0 6.2 25.5 0.0 3.8 28.8 0.1 0.0 0.0 0.0 14.3 0.0 0.0 0.0 14.0 48.1 0.0 0.0 5.7 0.0 10.5 2.7 18.9 17.8 5.5 0.0 0.0 2.7 0.0 13.8 0.0 10.7 6.6 0.0 0.0 1.0 0.0 0.0 15.2 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.5 21.3 18.9 26.2 24.9 26.1 17.9 13.4 26.1 9.6 19.2 20.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PGGHG "ATHL1, FLJ22635" ENSG00000142102 "Protein-glucosylgalactosylhydroxylysine glucosidase" Q32M88 11 289126-296107 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "pancreas: 657.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 160.3;Alveolar cells type 2: 81.8;Breast glandular cells: 35.1;Club cells: 31.6;Collecting duct cells: 33.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "JURKAT: 132.8;U-266/70: 34.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA039383, HPA058829" Uncertain Enhanced Cytosol NA Yes "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 25: Pancreas - Digestion" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" Cytosol "HPA039383: AB_10796225, HPA058829: AB_2683830" "unprognostic (1.40e-3)" "unprognostic (2.18e-1)" "unprognostic (4.22e-2)" "unprognostic (2.37e-1)" "unprognostic (1.36e-2)" "unprognostic (5.83e-2)" "unprognostic (7.95e-3)" "unprognostic (2.77e-2)" "unprognostic (2.16e-2)" "unprognostic (2.14e-2)" "unprognostic (2.71e-2)" "unprognostic (3.45e-1)" "unprognostic (1.92e-3)" "unprognostic (2.85e-3)" "unprognostic (1.09e-2)" "unprognostic (1.22e-1)" "prognostic favorable (5.12e-4)" 25.3 5.6 5.8 41.6 5.8 16.3 41.9 5.5 25.6 56.0 6.8 25.2 50.5 21.6 32.7 14.1 34.6 18.9 18.8 5.4 5.8 116.4 77.8 67.0 63.5 6.9 6.4 8.7 657.7 2.9 12.5 7.3 8.2 34.6 6.3 0.6 36.2 46.1 4.5 8.6 103.0 3.0 5.7 101.9 18.5 6.3 7.1 37.4 74.4 3.2 17.6 21.5 22.6 6.3 5.4 5.8 10.5 11.7 4.2 3.7 8.2 4.2 3.4 2.4 2.1 5.0 15.0 0.0 5.3 5.1 5.1 3.3 0.9 1.9 0.3 13.3 4.0 2.5 4.2 6.8 5.3 0.3 22.8 13.8 1.5 0.9 0.7 8.9 8.1 132.8 10.5 15.9 1.3 7.7 24.0 12.1 8.3 1.8 1.0 21.5 2.1 7.8 5.6 1.8 0.1 2.4 1.5 7.8 7.2 4.6 5.7 2.9 7.5 4.9 7.0 1.5 0.5 34.8 1.0 6.0 0.8 4.3 5.8 1.2 0.7 1.0 6.1 3.2 5.1 1.5 1.0 3.3 0.5 1.5 2.1 4.5 3.7 5.6 2.5 2.0 0.1 2.2 5.8 5.8 5.5 25.6 5.4 5.8 6.9 6.4 8.2 5.7 7.1 6.3 17.8 160.3 81.8 0.0 9.1 0.0 0.0 0.0 0.0 0.0 35.1 26.8 0.0 0.0 31.6 33.1 0.0 0.3 29.8 0.0 0.0 4.9 0.0 12.5 12.0 4.5 0.0 0.0 0.0 8.3 3.3 4.2 0.0 17.6 6.3 1.5 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 1.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 16.1 0.0 0.0 2.9 10.2 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.3 14.4 0.9 0.0 0.0 PHACTR4 "FLJ13171, PPP1R124" ENSG00000204138 "Phosphatase and actin regulator 4" Q8IZ21 1 28369582-28500364 "Predicted intracellular proteins" Neurogenesis "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 212.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028985 Approved Approved "Plasma membrane,Intermediate filaments,Cytosol" NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "Intermediate filaments" "HPA028985: AB_10602142" "unprognostic (1.55e-1)" "unprognostic (2.61e-2)" "unprognostic (4.50e-3)" "unprognostic (1.73e-1)" "unprognostic (5.27e-1)" "prognostic favorable (1.05e-4)" "unprognostic (9.65e-3)" "unprognostic (8.77e-2)" "unprognostic (2.03e-2)" "unprognostic (1.61e-1)" "unprognostic (1.05e-1)" "unprognostic (1.04e-1)" "unprognostic (2.94e-2)" "unprognostic (3.08e-1)" "unprognostic (4.81e-2)" "unprognostic (3.03e-2)" "unprognostic (2.26e-2)" 7.2 6.5 6.3 8.6 8.1 11.8 10.1 8.2 6.8 13.6 10.2 12.9 9.1 13.7 7.1 33.0 13.2 8.9 8.9 5.8 8.5 14.1 16.3 12.4 7.8 9.1 6.8 13.1 11.7 15.1 4.0 10.4 7.2 11.8 14.1 5.1 11.3 8.2 11.9 16.2 10.3 13.8 5.5 12.0 10.7 8.6 8.0 11.9 12.4 18.3 12.2 9.4 14.8 9.3 26.0 17.2 37.8 27.5 9.6 10.2 5.8 18.1 18.3 38.5 40.0 16.4 28.1 24.5 15.9 21.6 24.3 17.7 26.3 17.4 33.9 18.1 14.9 51.6 28.2 26.5 14.3 31.2 56.7 9.9 16.4 24.7 42.7 14.0 52.0 19.5 26.0 16.9 24.5 8.0 22.3 7.8 28.3 14.0 11.8 23.2 35.7 18.5 20.2 22.8 20.1 26.0 41.0 16.9 20.9 14.9 22.5 11.1 33.3 18.8 34.6 13.4 35.8 12.4 19.7 20.1 18.4 26.2 20.3 1.9 2.0 2.0 3.3 2.0 2.9 1.4 2.6 3.3 2.2 2.2 1.8 2.6 1.4 2.4 3.3 2.6 1.2 1.5 6.3 8.1 8.2 6.8 5.8 8.5 9.1 6.8 7.2 5.5 8.0 9.3 65.9 70.5 49.8 60.7 38.9 38.6 23.6 24.1 46.7 34.6 37.0 35.8 38.5 40.0 53.7 23.9 20.9 17.6 36.7 59.9 17.6 32.4 6.1 125.6 58.6 56.2 49.3 32.2 65.8 36.5 17.3 29.1 35.2 212.6 48.0 38.8 42.5 63.3 22.8 23.5 82.6 57.0 24.4 33.6 32.3 8.5 19.3 40.3 17.8 92.8 33.7 19.8 51.5 117.1 148.1 48.2 33.5 29.7 30.8 24.4 40.0 45.5 63.3 39.8 39.5 45.6 31.0 47.1 39.4 62.1 54.1 15.2 35.7 15.3 50.6 30.9 PIDD1 "DKFZp434D229, LRDD, MGC16925, PIDD" ENSG00000177595 "P53-induced death domain protein 1" Q9HB75 11 799179-809753 "Predicted intracellular proteins" Apoptosis Hydrolase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 29.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 26.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB012647, HPA055473, HPA066948" Supported Approved "Golgi apparatus,Cytosol" NA Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Golgi apparatus, Cytosol" "CAB012647: , HPA055473: AB_2682827, HPA066948: " "unprognostic (1.38e-1)" "prognostic favorable (8.19e-5)" "unprognostic (5.07e-3)" "prognostic favorable (3.32e-5)" "unprognostic (7.25e-2)" "prognostic favorable (3.91e-4)" "unprognostic (8.17e-3)" "unprognostic (5.97e-2)" "unprognostic (3.10e-1)" "unprognostic (1.03e-1)" "unprognostic (3.37e-3)" "unprognostic (2.17e-2)" "prognostic unfavorable (1.52e-4)" "unprognostic (2.84e-3)" "unprognostic (8.46e-2)" "unprognostic (2.24e-1)" "unprognostic (2.22e-2)" 3.3 3.1 2.3 2.3 2.8 7.4 3.3 2.5 4.1 3.6 2.8 3.9 3.0 3.0 0.1 4.0 3.3 1.1 2.9 2.1 2.2 3.1 5.5 2.7 3.2 3.6 2.6 2.8 3.7 0.9 2.8 1.9 3.5 4.3 0.6 0.2 3.2 1.0 6.5 5.5 4.5 0.7 2.5 5.0 4.0 2.4 3.0 3.2 3.8 0.8 1.0 3.2 3.1 4.6 5.4 6.2 2.9 6.2 0.6 2.2 26.6 7.5 2.0 2.7 3.6 5.7 10.2 4.4 2.3 1.1 2.5 7.9 2.1 3.0 0.5 9.0 12.3 3.8 5.0 12.0 6.8 4.3 9.4 8.4 5.3 1.4 0.3 0.5 5.0 10.3 4.5 3.3 1.1 2.6 12.0 7.2 4.0 5.8 4.3 19.4 4.2 8.6 1.1 1.9 5.1 6.8 3.1 8.2 2.0 1.6 6.0 7.3 2.7 3.4 7.6 2.5 4.9 10.5 6.4 8.5 4.4 3.5 5.6 0.0 0.5 0.0 0.4 0.4 0.4 0.3 0.3 0.4 0.8 0.4 0.4 0.4 0.0 0.1 0.4 0.2 0.9 0.4 2.3 2.8 2.5 4.1 2.1 2.2 3.6 2.6 3.5 2.5 3.0 4.6 4.9 3.2 8.8 25.8 7.2 0.0 3.6 0.0 6.2 14.9 7.3 8.1 4.2 5.7 5.6 3.7 10.4 29.2 8.9 12.0 1.9 2.5 1.4 6.7 4.2 3.7 9.0 5.7 12.8 4.6 7.5 4.4 10.7 4.2 1.3 14.0 2.2 10.3 5.5 1.7 14.2 8.1 0.0 3.5 0.0 1.9 7.2 3.8 0.0 7.5 4.1 7.0 2.1 6.6 26.9 3.5 9.9 4.1 6.0 4.4 10.0 3.8 0.0 15.4 0.0 5.7 3.5 25.2 20.8 6.7 0.0 9.7 6.3 7.5 10.5 3.6 PIF1 "C15orf20, FLJ22692" ENSG00000140451 "PIF1 5'-to-3' DNA helicase" Q9H611 15 64815632-64825668 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 4.8" "Cell type enhanced" "Detected in many" "Early spermatids: 21.3;Erythroid cells: 17.7;Granulosa cells: 15.1;NK-cells: 15.5;Theca cells: 18.3" "Cancer enhanced" "Detected in many" "testis cancer: 10.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" CAB018701 Supported Supported Nucleoplasm NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB018701: AB_2164654" "unprognostic (1.99e-1)" "unprognostic (6.11e-2)" "unprognostic (1.34e-1)" "unprognostic (3.12e-2)" "unprognostic (1.62e-1)" "unprognostic (8.33e-3)" "unprognostic (8.66e-4)" "unprognostic (1.47e-1)" "prognostic unfavorable (5.22e-4)" "unprognostic (6.68e-2)" "unprognostic (2.38e-2)" "unprognostic (3.27e-2)" "unprognostic (0.00e+0)" "unprognostic (2.96e-3)" "unprognostic (1.78e-1)" "unprognostic (9.61e-2)" "unprognostic (5.95e-2)" 0.7 1.0 0.8 2.6 0.8 3.8 0.4 0.7 1.3 0.9 0.7 2.4 1.9 0.8 0.1 3.1 0.7 0.8 0.9 0.7 1.2 0.6 0.6 1.0 4.6 1.4 1.0 0.4 0.2 0.2 0.5 0.9 1.1 1.7 1.0 0.1 0.6 0.7 0.3 1.0 2.6 1.2 0.9 4.8 1.8 2.5 1.2 3.6 0.5 0.1 3.3 1.5 1.4 0.8 7.7 8.7 21.1 8.6 3.7 4.3 7.8 7.4 3.9 7.3 5.6 14.0 12.6 9.3 3.0 3.6 6.8 20.9 21.8 6.2 2.7 14.8 8.0 10.8 28.5 10.2 1.9 4.3 8.4 2.5 0.0 3.2 2.6 1.8 7.5 13.6 7.2 18.0 7.0 6.7 4.7 17.9 17.2 9.7 6.0 9.7 7.0 13.0 4.1 4.3 8.7 5.6 5.7 6.3 3.3 9.2 7.0 4.7 5.2 4.4 22.6 7.0 14.0 14.3 14.3 9.0 4.2 18.8 6.4 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.1 0.8 0.8 0.7 1.3 0.7 1.2 1.4 1.0 1.1 0.9 1.2 0.8 1.2 0.0 1.1 3.6 6.5 1.9 0.8 0.6 0.0 0.5 0.6 0.6 1.9 0.0 0.1 0.0 0.0 5.1 7.5 3.2 0.0 0.0 21.3 0.4 4.4 2.3 0.0 17.7 2.6 0.0 6.5 5.6 3.6 0.7 0.0 15.1 5.3 0.5 5.8 0.0 1.0 2.4 0.0 5.1 2.0 2.3 1.5 4.5 0.0 1.9 0.1 0.8 15.5 3.5 0.1 0.2 0.1 2.2 9.7 1.1 0.2 0.1 0.1 1.2 6.6 4.2 3.5 0.8 2.0 1.6 1.0 1.1 7.5 18.3 6.2 1.3 PIGW "FLJ37433, Gwt1" ENSG00000277161 "Phosphatidylinositol glycan anchor biosynthesis class W" Q7Z7B1 17 36534987-36539310 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Acyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023499 Approved "Plasma membrane" No Yes "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane" "HPA023499: " "unprognostic (4.96e-3)" "unprognostic (3.84e-2)" "unprognostic (5.40e-3)" "unprognostic (7.39e-2)" "unprognostic (2.32e-1)" "unprognostic (7.71e-2)" "unprognostic (8.14e-3)" "unprognostic (1.05e-1)" "unprognostic (1.89e-1)" "unprognostic (4.62e-2)" "unprognostic (1.98e-1)" "unprognostic (3.29e-1)" "unprognostic (1.73e-2)" "unprognostic (1.41e-1)" "unprognostic (8.96e-2)" "unprognostic (1.08e-3)" "unprognostic (1.88e-1)" 4.5 3.8 1.0 3.9 1.1 2.7 3.9 1.4 1.5 3.2 1.8 4.3 2.6 4.2 2.0 7.4 3.4 1.9 3.7 1.0 1.5 6.5 6.5 3.7 3.8 1.5 1.2 2.5 4.7 2.6 4.0 2.0 1.5 3.3 3.6 1.8 5.0 1.3 8.2 5.8 4.3 2.6 1.1 4.4 4.5 2.8 1.4 2.1 4.1 3.4 3.5 3.6 4.3 1.3 10.8 15.2 9.0 9.2 4.9 4.2 15.0 11.6 6.2 12.2 9.3 11.7 12.2 19.9 3.8 7.9 14.9 15.7 16.5 8.0 16.1 11.3 23.3 14.7 7.3 11.0 3.8 32.2 17.2 5.2 9.6 12.5 5.4 2.5 7.9 6.3 26.9 9.5 8.9 10.1 16.4 11.2 16.5 7.5 13.0 15.3 24.0 18.8 7.6 11.6 20.7 16.7 21.0 8.6 9.3 8.4 27.8 4.7 10.4 21.7 29.1 20.8 26.1 8.8 32.8 22.0 5.2 18.0 19.6 0.8 1.7 0.3 2.0 2.7 2.8 1.5 2.6 2.1 3.5 2.9 3.2 3.1 0.4 2.6 3.5 2.1 1.6 2.2 1.0 1.1 1.4 1.5 1.0 1.5 1.5 1.2 1.5 1.1 1.4 1.3 3.6 3.2 3.1 1.6 4.6 3.4 9.5 4.6 12.5 2.2 4.3 2.9 1.6 10.0 4.2 0.0 0.0 6.1 5.4 2.9 7.9 6.8 0.2 2.4 3.6 4.7 1.2 12.6 2.0 6.4 6.7 3.8 5.1 2.7 0.0 2.3 1.1 6.0 4.5 3.3 2.6 4.0 0.0 3.3 2.2 0.6 2.8 3.5 0.0 0.0 3.1 4.2 1.0 1.5 2.5 7.1 3.6 2.2 4.9 10.2 1.0 4.9 2.8 3.1 0.0 3.7 3.6 3.4 7.4 9.4 6.8 4.1 3.1 3.5 5.6 5.3 PIK3IP1 "HGFL, MGC17330, TrIP" ENSG00000100100 "Phosphoinositide-3-kinase interacting protein 1" Q96FE7 22 31281594-31292534 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "T-cells: 143.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive CD4 T-cell: 499.2" "Lineage enriched" "Detected in all" 6 "T-cells: 499.2" "Cell line enhanced" "Detected in many" "RT4: 24.1;SK-BR-3: 26.1;U-698: 34.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA Yes 6800000 "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.02e-1)" "unprognostic (1.97e-3)" "unprognostic (1.58e-1)" "unprognostic (4.84e-2)" "unprognostic (8.19e-2)" "unprognostic (1.61e-3)" "unprognostic (5.78e-2)" "unprognostic (1.63e-3)" "unprognostic (2.82e-1)" "unprognostic (1.40e-1)" "unprognostic (1.99e-1)" "unprognostic (9.95e-3)" "unprognostic (1.28e-2)" "unprognostic (2.65e-3)" "unprognostic (4.42e-2)" "unprognostic (8.68e-2)" "prognostic favorable (3.80e-4)" 51.2 41.7 35.4 59.3 42.5 41.7 39.5 38.3 40.2 21.4 23.7 35.5 17.5 34.9 13.2 21.7 24.1 27.0 34.8 33.4 39.3 27.6 9.3 45.7 109.8 53.5 40.4 22.8 11.3 16.9 15.1 25.3 48.5 27.1 15.5 11.4 52.4 31.7 20.9 58.2 61.6 22.9 43.8 71.3 24.7 20.3 42.4 68.2 37.6 16.1 79.7 34.8 27.1 52.7 0.5 0.2 0.8 0.1 11.8 20.4 0.9 3.1 9.7 0.2 1.1 0.3 20.4 15.9 11.4 4.9 1.3 13.4 0.1 5.8 0.2 2.6 1.9 0.5 2.3 2.2 4.0 1.1 0.7 20.0 8.3 0.2 0.1 18.9 6.4 2.3 0.9 19.6 1.5 1.3 0.1 2.5 0.9 1.8 0.4 1.2 0.8 11.9 5.1 24.1 1.2 2.6 1.0 26.1 1.2 10.7 2.1 2.3 20.0 0.0 4.5 0.2 0.0 8.9 4.1 34.7 0.5 2.8 0.4 46.0 18.4 16.5 79.7 22.8 95.5 38.2 207.1 113.7 5.9 79.3 499.2 318.3 7.6 59.2 34.2 2.6 257.0 214.7 35.4 42.5 38.3 40.2 33.4 39.3 53.5 40.4 48.5 43.8 42.4 52.7 26.1 44.8 12.3 17.6 63.7 10.3 19.0 44.6 5.7 29.9 15.5 11.3 11.3 10.0 36.9 31.3 10.4 30.7 89.8 8.3 1.9 50.2 1.6 10.6 10.3 20.9 8.4 12.0 6.5 10.5 3.7 23.8 10.7 24.4 30.4 10.1 32.9 2.0 45.1 6.7 8.6 13.1 32.6 42.5 11.4 3.8 24.5 40.3 12.4 9.4 19.2 82.0 74.2 9.5 25.1 51.7 8.6 30.9 33.1 23.4 19.8 7.9 25.1 9.2 6.6 10.2 14.6 16.5 32.3 4.9 11.5 12.3 143.6 27.4 10.1 60.0 PILRB "FDFACT1, FDFACT2" ENSG00000121716 "Paired immunoglobin like type 2 receptor beta" Q9UKJ0 7 100352176-100367733 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 221.1;neutrophil: 141.8" "Group enriched" "Detected in all" 8 "granulocytes: 221.1;monocytes: 75.5" "Cell line enhanced" "Detected in all" "SK-BR-3: 344.6" HPA026750 Approved Approved Mitochondria "Intracellular and membrane" NA Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Mitochondria "HPA026750: AB_10670828" "unprognostic (8.33e-3)" "unprognostic (9.31e-2)" "unprognostic (1.32e-2)" "unprognostic (9.15e-2)" "unprognostic (1.02e-1)" "unprognostic (1.30e-1)" "unprognostic (3.62e-2)" "unprognostic (3.17e-1)" "unprognostic (1.20e-1)" "unprognostic (8.76e-2)" "unprognostic (2.54e-2)" "unprognostic (6.27e-2)" "prognostic unfavorable (1.42e-4)" "unprognostic (4.85e-3)" "unprognostic (1.66e-1)" "unprognostic (4.40e-2)" "unprognostic (3.35e-3)" 63.2 89.0 72.9 71.0 75.0 71.7 77.6 104.3 86.3 87.0 90.9 65.8 66.1 62.9 67.6 47.2 83.8 52.2 47.7 75.5 70.8 118.8 125.0 43.9 83.7 71.8 70.8 82.1 91.7 58.3 182.0 32.9 71.5 102.7 57.4 66.8 66.4 58.0 78.7 90.1 75.9 42.3 64.2 113.5 68.7 157.5 74.3 59.0 122.9 34.3 65.7 61.9 56.2 78.1 62.5 51.4 57.9 100.7 63.0 14.4 56.2 37.0 16.5 25.7 24.9 36.5 70.3 50.3 68.0 19.0 45.7 65.1 32.3 38.9 17.5 41.6 47.3 46.5 204.8 32.2 14.0 47.4 116.0 18.1 44.8 34.8 70.2 31.9 21.8 73.6 50.7 118.9 18.3 83.9 74.8 243.3 25.2 51.7 26.9 43.3 16.9 51.6 116.4 100.3 53.8 38.5 31.2 344.6 45.7 61.7 60.5 72.3 52.4 90.8 57.9 58.8 48.7 71.2 98.6 61.8 25.5 69.4 54.6 21.2 35.6 221.1 10.7 59.2 6.7 0.6 1.3 7.1 17.8 1.6 1.2 2.6 141.8 17.9 75.5 0.5 0.6 25.7 72.9 75.0 104.3 86.3 75.5 70.8 71.8 70.8 71.5 64.2 74.3 78.1 22.8 38.5 45.9 0.0 25.3 15.7 18.1 17.1 11.4 44.7 32.9 33.7 1.1 44.3 32.2 14.7 68.8 12.9 49.5 12.3 1.9 7.6 18.4 43.1 17.5 19.8 29.4 7.4 0.0 5.6 12.1 13.4 36.2 57.2 25.2 26.0 24.3 77.7 10.0 75.7 0.0 21.2 22.4 16.0 16.6 13.6 74.0 11.7 19.6 0.0 10.0 19.0 134.9 0.0 0.0 7.4 16.2 51.1 14.5 17.9 20.3 4.9 40.3 64.9 26.3 18.2 14.3 49.4 10.2 10.5 13.5 15.7 37.0 23.5 22.4 16.7 PIM3 ENSG00000198355 "Pim-3 proto-oncogene, serine/threonine kinase" Q86V86 22 49960768-49964072 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 408.4;Syncytiotrophoblasts: 389.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 20.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 163.3;SK-BR-3: 144.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068758 Supported Cytosol NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Cytosol "HPA068758: AB_2686026" "unprognostic (3.67e-2)" "unprognostic (7.69e-3)" "unprognostic (1.07e-1)" "unprognostic (1.11e-1)" "unprognostic (3.67e-2)" "unprognostic (5.83e-2)" "unprognostic (1.48e-2)" "unprognostic (1.13e-2)" "unprognostic (2.71e-2)" "prognostic unfavorable (9.68e-4)" "unprognostic (2.00e-2)" "unprognostic (1.00e-1)" "prognostic favorable (8.09e-4)" "unprognostic (5.59e-3)" "unprognostic (1.71e-1)" "unprognostic (3.92e-3)" "unprognostic (7.27e-3)" 97.8 48.4 25.9 31.3 31.3 114.3 80.2 32.8 38.1 49.2 26.9 55.1 23.8 40.8 12.7 80.8 54.0 25.8 68.7 25.2 32.6 113.3 92.9 107.1 28.2 40.6 36.1 35.7 73.1 21.6 51.3 21.3 38.0 87.3 10.4 3.1 93.5 22.6 112.0 116.4 51.6 9.9 30.3 80.7 118.1 33.9 35.2 19.0 54.9 35.0 13.0 71.0 68.6 39.9 26.8 17.7 11.6 21.9 9.0 6.7 65.5 16.5 26.7 19.4 14.0 29.5 22.3 47.3 20.1 4.6 39.1 22.5 22.3 12.6 6.9 35.8 92.1 19.5 46.3 36.0 41.8 42.5 36.0 12.8 41.0 11.9 20.2 10.5 63.5 31.7 27.0 163.3 5.9 60.6 21.7 76.4 24.2 28.1 27.8 100.3 19.2 57.6 10.6 20.3 41.1 28.6 32.2 144.7 109.2 10.7 19.0 56.4 16.8 12.1 51.5 19.8 27.1 82.2 56.9 41.4 30.1 24.1 33.2 0.0 4.0 0.1 2.2 4.1 2.5 4.3 5.0 4.4 3.1 7.5 4.8 1.9 20.7 1.7 5.2 7.0 5.8 2.7 25.9 31.3 32.8 38.1 25.2 32.6 40.6 36.1 38.0 30.3 35.2 39.9 120.2 64.1 85.9 6.5 107.7 227.3 236.8 79.1 96.8 31.5 99.2 67.3 32.8 121.5 72.8 80.9 2.1 56.9 79.5 57.9 84.1 50.9 5.1 114.2 76.3 167.7 97.7 10.8 10.2 54.5 346.5 69.0 202.3 170.5 69.3 16.8 98.6 45.9 69.7 62.2 6.7 101.7 81.4 41.1 408.4 4.8 32.3 134.8 108.5 6.5 35.8 14.0 11.3 6.6 20.5 71.0 94.6 11.3 95.1 298.4 58.1 88.5 40.9 16.5 26.3 39.4 57.3 26.1 37.7 95.3 204.7 389.9 90.4 11.6 79.0 266.0 PIMREG "CATS, FAM64A, FLJ10156, FLJ10491, RCS1" ENSG00000129195 "PICALM interacting mitotic regulator" Q9BSJ6 17 6444441-6451469 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 13.9" "Group enriched" "Detected in some" 6 "Fibroblasts: 5.5;Granulosa cells: 21.5;Hofbauer cells: 7.2;Smooth muscle cells: 14.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.1" "Immune cell enhanced" "Detected in single" "NK-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 161.8" "Region enhanced" "Detected in many" "white matter: 5.7" "Low region specificity" "Detected in single" "HPA043783, HPA049934" Uncertain Enhanced Nucleoplasm Yes Yes "Cluster 22: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA043783: AB_2678669, HPA049934: AB_2680959" "unprognostic (5.32e-3)" "unprognostic (1.14e-2)" "unprognostic (2.33e-1)" "unprognostic (4.37e-3)" "unprognostic (1.46e-1)" "unprognostic (1.24e-2)" "unprognostic (6.55e-3)" "unprognostic (1.23e-3)" "unprognostic (1.80e-1)" "unprognostic (5.88e-2)" "unprognostic (1.47e-3)" "unprognostic (1.50e-2)" "unprognostic (0.00e+0)" "unprognostic (8.65e-2)" "unprognostic (1.04e-1)" "unprognostic (1.01e-1)" "unprognostic (1.11e-1)" 0.5 2.5 0.3 1.3 0.0 2.5 0.8 1.1 0.4 0.9 0.0 3.3 3.0 0.8 0.0 3.3 0.3 0.7 0.3 0.1 0.1 0.3 0.3 0.7 1.5 0.2 0.0 0.8 0.2 0.1 0.1 0.6 0.0 0.3 4.1 0.4 0.7 0.1 0.0 2.7 3.1 2.0 0.0 6.0 1.2 0.3 0.1 13.9 0.4 0.0 2.1 1.3 1.3 0.2 42.1 54.1 161.8 73.1 1.5 4.5 12.6 47.9 29.8 78.6 52.5 32.8 17.9 0.0 18.8 39.8 39.9 29.9 82.6 21.6 41.9 64.6 33.9 0.1 33.8 41.2 0.2 1.7 48.9 2.4 1.5 32.2 12.4 8.0 24.8 36.8 10.1 23.0 49.9 30.5 9.2 0.5 70.9 34.0 37.8 74.9 64.8 29.6 12.9 6.4 36.5 51.3 41.7 42.5 39.1 20.4 19.9 4.0 11.9 59.9 48.4 36.0 80.7 8.2 31.5 0.2 23.6 20.4 94.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.1 0.0 0.1 0.2 1.0 0.1 0.0 0.3 0.3 0.3 0.0 1.1 0.4 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 1.8 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.2 0.0 0.4 1.2 0.6 0.0 0.0 0.0 0.0 0.6 5.5 0.0 0.7 1.3 21.5 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 14.5 0.0 0.0 0.0 0.0 0.1 0.8 1.1 0.0 0.0 PKMYT1 "MYT1, PPP1R126" ENSG00000127564 "Protein kinase, membrane associated tyrosine/threonine 1" Q99640 16 2968024-2980479 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.6;testis: 56.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 29.0;Extravillous trophoblasts: 52.0;Plasma cells: 22.9;Spermatocytes: 114.7;Spermatogonia: 46.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 6 "T-reg: 1.3" "Lineage enriched" "Detected in single" 6 "T-cells: 1.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA068860 Supported "Nucleoplasm,Nucleoli,Golgi apparatus" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 23: Testis - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA068860: AB_2686050" "unprognostic (7.82e-2)" "unprognostic (8.70e-2)" "unprognostic (5.93e-2)" "unprognostic (2.04e-2)" "unprognostic (4.54e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (8.33e-4)" "prognostic unfavorable (3.37e-4)" "unprognostic (4.52e-2)" "unprognostic (2.15e-1)" "unprognostic (1.61e-2)" "unprognostic (7.95e-3)" "unprognostic (0.00e+0)" "unprognostic (1.09e-3)" "unprognostic (9.13e-2)" "unprognostic (1.96e-1)" "unprognostic (5.91e-2)" 1.1 1.0 0.4 6.8 0.5 27.6 0.6 1.6 1.4 2.2 0.2 3.9 2.8 0.6 0.3 11.5 0.4 0.6 0.9 0.5 0.2 0.9 1.6 2.0 8.0 0.7 0.6 0.3 1.8 0.1 1.0 3.1 0.8 1.0 1.3 17.4 1.9 0.1 2.4 4.4 4.0 1.0 0.5 5.6 3.3 56.9 0.7 9.6 0.5 0.0 4.5 0.7 3.3 0.8 84.2 57.0 22.0 31.2 0.3 0.9 64.0 65.5 15.1 40.0 38.4 45.0 49.3 54.2 29.2 7.9 24.2 106.7 15.7 20.7 7.2 71.7 56.7 27.9 52.7 40.0 0.0 31.2 73.6 0.7 1.8 24.0 6.5 5.0 8.4 57.6 80.6 87.0 13.5 127.5 83.6 88.0 37.9 39.3 34.4 93.7 51.2 100.7 7.8 17.7 42.6 46.7 31.9 77.7 23.9 12.1 44.7 56.9 7.7 53.2 69.7 77.3 68.0 67.6 54.2 94.0 19.4 40.0 61.2 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.3 0.3 0.4 0.5 1.6 1.4 0.5 0.2 0.7 0.6 0.8 0.5 0.7 0.8 0.0 0.0 1.1 0.0 1.9 2.5 1.3 2.1 0.6 0.4 1.5 1.3 0.6 1.5 1.6 1.8 6.2 16.0 1.3 5.0 0.0 0.8 20.0 0.6 0.8 0.8 1.8 29.0 0.4 0.6 52.0 2.5 3.1 1.9 0.0 4.5 0.0 0.4 11.8 0.0 0.2 3.6 6.1 2.1 1.8 8.6 0.3 1.9 0.0 0.0 0.7 0.2 0.0 0.0 0.3 0.6 0.3 0.4 22.9 0.7 0.3 0.1 0.2 7.1 0.0 0.1 2.6 114.7 46.1 11.2 0.6 7.4 4.2 0.5 8.6 2.0 PLCXD1 FLJ11323 ENSG00000182378 "Phosphatidylinositol specific phospholipase C X domain containing 1" Q9NUJ7 X 276322-303356 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 34.7;Distal enterocytes: 34.2;Gastric mucus-secreting cells: 33.1;Paneth cells: 40.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 110.4;HEL: 172.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA007721 Approved Approved Cytosol NA Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 36: HEL - Hemostasis" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA007721: AB_1079630" "unprognostic (2.73e-2)" "unprognostic (5.67e-2)" "unprognostic (4.57e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (3.80e-2)" "prognostic favorable (2.50e-4)" "unprognostic (1.47e-3)" "unprognostic (7.92e-2)" "unprognostic (1.72e-2)" "unprognostic (4.80e-2)" "unprognostic (7.25e-2)" "unprognostic (1.11e-3)" "prognostic unfavorable (7.82e-14)" "unprognostic (6.01e-2)" "unprognostic (1.95e-1)" "unprognostic (3.59e-2)" "unprognostic (1.78e-1)" 14.7 4.1 4.6 9.4 8.8 32.9 9.7 13.0 19.2 10.0 0.0 8.2 8.6 5.6 1.4 17.5 9.1 8.8 5.6 4.4 0.0 5.7 10.1 7.4 17.3 3.4 1.5 12.8 7.5 3.2 7.7 7.8 4.4 7.5 5.7 6.0 11.4 3.7 8.4 18.7 12.5 2.7 0.5 17.5 26.9 6.7 4.0 8.9 10.4 2.7 9.0 6.1 9.7 13.4 28.4 110.4 25.7 38.8 5.0 3.9 20.4 24.4 2.9 12.8 12.4 40.6 29.1 34.8 17.9 10.7 19.0 8.5 6.3 15.9 6.7 21.2 46.2 172.6 36.1 59.7 15.6 17.4 63.1 20.1 1.9 47.0 4.9 8.6 9.7 57.2 44.0 18.7 9.2 8.2 52.3 24.2 57.8 7.1 19.2 29.1 13.3 53.9 3.9 12.9 25.9 15.0 24.6 14.4 21.1 17.5 27.6 22.0 7.2 17.1 28.2 18.5 26.9 6.3 17.9 86.4 11.0 44.4 18.2 3.7 2.7 5.4 1.9 6.0 2.7 1.6 1.4 2.4 2.0 5.6 1.8 1.9 3.3 1.2 9.0 2.1 3.2 2.3 4.6 8.8 13.0 19.2 4.4 0.0 3.4 1.5 4.4 0.5 4.0 13.4 15.8 9.6 34.7 5.5 4.1 6.9 13.6 3.9 2.2 7.4 4.7 3.6 6.5 10.0 2.8 0.0 2.1 10.1 4.9 34.2 0.0 6.3 0.9 1.6 3.4 6.1 3.0 9.9 5.3 1.8 11.3 6.1 33.1 3.2 3.8 32.1 4.6 6.9 5.5 8.4 6.1 11.2 0.0 7.3 9.8 0.9 2.5 11.9 0.0 5.6 3.7 2.3 9.2 0.5 5.7 18.8 40.9 3.8 2.7 5.3 3.0 1.7 1.3 7.1 13.1 6.5 7.9 8.4 15.9 4.2 8.7 27.0 3.8 2.8 9.4 8.0 PLIN3 "M6PRBP1, PP17, TIP47" ENSG00000105355 "Perilipin 3" O60664 19 4838341-4867694 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 268.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006427, HPA066538" Uncertain Supported "Lipid droplets" NA Yes 11000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Lipid droplets" "HPA006427: AB_1079289, HPA066538: AB_2685687" "unprognostic (1.18e-1)" "unprognostic (4.86e-2)" "unprognostic (1.55e-2)" "prognostic favorable (2.62e-4)" "unprognostic (2.94e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (3.27e-5)" "prognostic unfavorable (7.67e-6)" "unprognostic (2.27e-1)" "unprognostic (1.28e-1)" "unprognostic (4.34e-2)" "unprognostic (8.24e-2)" "prognostic unfavorable (9.15e-7)" "unprognostic (2.62e-1)" "unprognostic (2.14e-1)" "unprognostic (1.95e-1)" "unprognostic (2.39e-2)" 30.8 69.9 23.3 41.4 39.6 70.8 29.5 44.2 27.5 50.4 25.9 37.6 70.8 22.6 14.4 124.7 22.9 34.5 25.3 22.1 28.6 38.0 26.5 25.7 29.1 51.1 36.1 40.0 20.3 9.8 9.3 33.3 48.9 28.0 20.9 1.7 45.9 21.0 112.0 87.5 73.9 23.9 36.2 32.3 28.5 34.3 39.1 28.0 24.8 36.4 33.0 37.5 55.4 66.0 138.2 79.1 53.6 50.5 59.8 189.8 24.1 196.8 178.9 152.0 142.9 52.6 124.9 72.5 43.3 242.2 82.1 61.3 25.1 108.2 88.2 82.7 35.4 79.1 43.0 97.8 41.4 56.7 112.9 147.1 46.2 107.4 23.6 90.5 81.2 23.5 122.4 31.3 192.1 57.1 78.3 72.9 42.5 63.3 127.7 136.2 74.9 40.2 133.8 31.7 2.3 26.3 62.5 55.5 49.5 43.2 70.4 125.9 125.1 83.3 80.5 333.8 102.9 44.1 58.9 50.8 250.7 79.6 97.3 128.3 141.7 64.8 13.8 100.4 14.6 46.3 24.7 15.9 109.1 36.3 19.4 12.4 173.9 39.5 76.7 82.8 34.1 86.4 23.3 39.6 44.2 27.5 22.1 28.6 51.1 36.1 48.9 36.2 39.1 66.0 19.2 19.2 25.6 5.5 28.5 142.2 62.9 58.8 90.0 0.4 108.0 43.1 2.3 14.3 51.3 11.0 2.1 152.2 34.4 169.7 37.2 114.7 9.7 65.2 50.9 27.7 40.7 18.5 0.8 86.8 77.3 62.9 33.1 78.4 55.8 112.9 26.0 18.2 101.2 0.0 1.1 67.0 28.5 57.8 103.4 14.0 35.8 74.7 55.2 2.8 62.3 23.9 15.5 5.0 17.1 243.4 223.0 53.0 37.1 39.3 268.8 38.8 65.2 0.7 52.6 37.8 66.2 75.1 14.6 109.0 229.3 194.8 20.3 193.4 54.8 69.2 PLK1 PLK ENSG00000166851 "Polo like kinase 1" P53350 16 23677656-23690367 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.0;lymphoid tissue: 43.9;testis: 33.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 32.3;Early spermatids: 123.7;Erythroid cells: 38.3;Extravillous trophoblasts: 55.9;Spermatocytes: 79.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "T-reg: 5.6" "Lineage enriched" "Detected in many" 5 "T-cells: 5.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA051638, HPA053229" Approved NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA051638: AB_2681561, HPA053229: AB_2682084" "unprognostic (7.21e-3)" "unprognostic (1.77e-1)" "unprognostic (1.98e-3)" "unprognostic (4.97e-3)" "unprognostic (9.56e-2)" "unprognostic (5.12e-2)" "prognostic unfavorable (2.70e-7)" "prognostic unfavorable (2.28e-5)" "unprognostic (2.55e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (4.12e-4)" "unprognostic (1.24e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.33e-1)" "unprognostic (8.10e-2)" "unprognostic (1.19e-1)" "unprognostic (1.26e-2)" 1.4 1.5 2.3 13.4 2.3 32.0 1.5 2.5 3.2 2.3 2.0 9.6 10.4 1.2 0.4 13.9 1.0 1.4 1.0 2.3 2.1 1.4 1.9 1.9 27.8 2.3 2.3 1.3 1.1 0.2 1.2 6.4 2.2 1.2 10.1 1.2 2.4 0.3 1.0 5.7 9.2 4.0 2.0 9.1 6.2 33.1 2.5 43.9 0.9 0.4 30.0 2.8 4.0 2.8 199.9 207.5 166.2 90.9 5.2 11.7 92.8 111.0 74.5 172.5 127.0 184.3 131.0 99.1 56.3 76.5 90.1 112.8 229.5 93.5 206.1 139.5 128.0 125.2 163.4 257.1 1.7 147.5 133.7 4.8 5.2 124.7 125.2 21.6 127.9 127.5 200.7 133.9 134.8 187.8 139.8 151.4 189.5 82.1 103.5 217.2 111.7 160.0 49.3 43.9 94.3 65.3 126.8 88.9 55.8 94.4 114.4 92.1 65.1 82.7 102.7 79.9 194.1 93.2 156.8 173.6 69.3 127.7 137.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.8 0.3 0.3 0.0 0.0 0.0 0.4 0.9 0.0 0.0 5.6 1.4 2.3 2.3 2.5 3.2 2.3 2.1 2.3 2.3 2.2 2.0 2.5 2.8 0.6 3.2 0.0 3.3 7.6 1.3 1.2 6.5 0.0 1.4 1.7 2.3 0.6 0.0 1.4 0.0 4.2 32.3 0.4 5.5 0.0 0.8 123.7 3.4 1.3 2.5 0.0 38.3 3.1 0.8 55.9 4.7 10.2 1.8 1.3 19.9 3.3 1.1 20.8 0.0 2.3 7.3 4.1 6.9 3.2 13.9 1.2 7.2 0.0 2.8 0.4 1.1 0.0 1.5 2.3 1.2 0.3 0.7 23.0 2.0 1.5 0.1 1.3 1.3 0.0 2.3 6.1 79.5 13.5 12.2 1.8 3.8 2.5 1.2 17.9 2.0 PLPP3 "LPP3, PAP-2b, PPAP2B" ENSG00000162407 "Phospholipid phosphatase 3" O14495 1 56494761-56645301 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 392.7;Hepatic stellate cells: 779.6;Leydig cells: 1092.6;Peritubular cells: 398.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 168.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 2.4;naive B-cell: 2.3" "Lineage enriched" "Detected in single" 6 "B-cells: 2.4" "Cell line enhanced" "Detected in many" "ASC diff: 710.0;ASC TERT1: 351.8;HSkMC: 438.1;U-2197: 660.4" "Low region specificity" "Detected in all" HPA072751 Approved Supported "Golgi apparatus" NA Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA072751: AB_2686555" "unprognostic (2.50e-2)" "unprognostic (3.94e-1)" "unprognostic (1.81e-1)" "unprognostic (1.65e-1)" "unprognostic (2.71e-1)" "unprognostic (2.22e-3)" "unprognostic (5.86e-3)" "unprognostic (7.25e-2)" "unprognostic (1.59e-1)" "unprognostic (3.75e-2)" "unprognostic (3.91e-2)" "unprognostic (3.08e-1)" "prognostic favorable (4.59e-4)" "unprognostic (3.16e-2)" "unprognostic (1.74e-1)" "unprognostic (3.54e-2)" "unprognostic (2.09e-1)" 168.4 53.0 93.9 33.6 94.2 13.1 139.8 87.3 105.9 294.6 50.7 56.7 24.0 107.2 56.2 51.3 122.5 66.3 84.6 88.3 90.6 91.4 182.0 87.0 22.4 107.5 108.1 81.9 36.8 130.2 23.1 225.5 87.7 102.8 41.8 19.0 76.2 169.7 50.9 82.1 45.8 65.6 86.8 23.3 66.0 37.3 113.2 29.8 327.6 63.0 19.9 139.2 142.8 88.6 3.3 10.8 14.1 1.5 710.0 351.8 34.5 39.3 39.7 35.5 17.4 31.8 6.2 5.2 4.6 59.3 39.4 5.9 2.1 0.8 7.4 0.0 9.4 1.3 4.4 44.5 17.3 0.1 0.0 438.1 3.0 34.2 28.6 25.1 34.1 0.4 2.9 0.1 39.0 3.2 0.1 0.5 43.3 9.2 42.6 0.1 0.1 1.7 6.1 32.6 0.4 28.1 12.4 16.1 4.2 42.6 5.2 0.0 21.6 176.2 14.4 660.4 1.8 0.0 0.0 0.0 31.0 1.7 12.7 0.0 0.1 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 2.3 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.1 93.9 94.2 87.3 105.9 88.3 90.6 107.5 108.1 87.7 86.8 113.2 88.6 148.5 25.6 18.9 0.0 7.2 0.0 19.8 0.0 35.3 3.9 12.2 31.2 0.0 44.3 13.0 22.0 0.0 127.0 1.1 8.1 21.5 21.5 7.9 13.9 139.4 148.3 2.4 8.0 0.0 9.2 9.8 392.7 5.6 16.3 3.8 8.1 779.6 132.6 38.8 0.0 0.0 8.5 0.0 35.2 0.0 28.3 1092.6 14.9 0.0 0.0 0.9 136.0 0.0 0.0 0.0 7.9 5.9 398.7 7.1 20.8 15.5 21.3 4.4 4.1 138.1 179.7 107.2 4.5 3.4 16.4 0.0 214.9 5.0 22.4 7.2 20.1 PLSCR1 MMTRA1B ENSG00000188313 "Phospholipid scramblase 1" O15162 3 146515180-146544856 "Predicted intracellular proteins, Transporters" "Antiviral defense, Host-virus interaction" "DNA-binding, Host cell receptor for virus entry, Hydrolase, Nuclease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 291.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 319.8;BJ hTERT+ SV40 Large T+ RasG12V: 418.6;HHSteC: 292.9;SK-MEL-30: 569.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068923, CAB070421" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Plasma membrane" "Golgi apparatus" "CAB070421: AB_11153452, HPA068923: AB_2686059" "unprognostic (7.88e-2)" "unprognostic (1.10e-1)" "unprognostic (5.34e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.12e-1)" "unprognostic (3.35e-1)" "unprognostic (5.22e-2)" "unprognostic (7.73e-3)" "unprognostic (9.19e-3)" "unprognostic (6.93e-3)" "unprognostic (3.07e-3)" "unprognostic (1.10e-1)" "unprognostic (1.09e-3)" "unprognostic (5.26e-2)" "unprognostic (1.64e-2)" "unprognostic (1.76e-1)" "unprognostic (1.63e-1)" 60.6 23.0 11.4 86.7 12.5 64.4 45.9 12.7 17.6 25.9 11.9 65.0 39.8 28.2 31.0 47.9 40.0 66.1 24.3 12.1 13.5 71.9 49.2 49.3 40.6 17.4 14.2 34.9 38.3 16.8 15.4 56.3 15.3 23.7 59.5 9.8 49.1 49.6 10.8 13.6 45.4 41.9 16.2 64.5 44.0 17.1 14.7 30.0 27.8 17.6 39.4 68.1 29.5 14.0 106.2 41.5 26.4 12.1 40.9 65.0 40.5 32.6 88.4 319.8 418.6 34.0 88.1 8.4 75.6 20.6 245.9 86.2 21.2 32.7 56.6 32.9 21.6 66.1 12.5 25.2 292.9 40.3 35.4 106.3 53.3 36.6 182.3 52.6 49.4 19.1 44.7 104.0 66.9 41.0 30.6 16.1 25.8 71.6 37.6 27.4 28.1 2.9 95.9 29.6 16.3 0.0 42.6 20.9 569.9 35.8 20.7 46.8 30.6 26.9 22.7 59.1 55.8 79.2 15.6 0.4 27.0 29.0 23.3 41.1 157.6 44.3 20.8 159.6 30.0 25.2 13.5 18.5 105.8 19.7 9.3 13.9 100.0 57.8 94.8 28.5 8.3 79.3 11.4 12.5 12.7 17.6 12.1 13.5 17.4 14.2 15.3 16.2 14.7 14.0 191.4 35.3 43.0 12.7 28.2 37.0 106.5 92.1 26.2 0.7 36.0 22.6 7.3 124.4 110.4 95.6 0.0 53.7 25.4 134.2 74.3 291.6 2.0 56.1 24.5 135.2 33.1 18.3 7.1 217.4 114.1 74.8 47.9 58.2 28.4 60.5 100.6 29.7 139.9 0.0 9.0 71.5 79.3 86.2 162.9 6.8 114.9 185.5 48.0 35.6 72.3 64.3 32.0 7.1 0.3 157.6 110.3 45.9 18.2 79.6 40.7 75.0 133.5 1.6 39.5 63.4 59.2 1.5 2.4 21.8 28.6 44.5 25.9 42.6 69.4 211.9 PNO1 "KHRBP1, RRP20" ENSG00000115946 "Partner of NOB1 homolog" Q9NRX1 2 68157888-68176238 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056928 Supported Nucleoplasm,Nucleoli NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoli Nucleoplasm "HPA056928: " "unprognostic (1.81e-3)" "unprognostic (4.83e-1)" "unprognostic (5.93e-2)" "prognostic unfavorable (1.12e-4)" "unprognostic (5.88e-2)" "unprognostic (1.66e-3)" "prognostic unfavorable (3.04e-8)" "unprognostic (5.82e-2)" "unprognostic (2.59e-2)" "unprognostic (1.16e-1)" "unprognostic (9.13e-3)" "unprognostic (3.33e-2)" "unprognostic (1.46e-2)" "unprognostic (1.42e-1)" "unprognostic (2.58e-1)" "unprognostic (3.74e-2)" "unprognostic (7.66e-2)" 15.1 14.2 6.4 12.1 8.0 19.5 11.6 7.0 11.8 7.6 6.9 9.7 7.6 9.8 11.2 11.1 8.8 9.9 10.2 12.0 7.3 14.1 12.6 8.6 12.6 6.7 6.9 7.0 12.7 12.5 7.1 12.7 6.8 10.0 9.1 19.0 7.1 10.8 20.1 9.1 6.7 11.5 6.7 8.2 8.8 8.9 6.9 8.1 12.5 12.6 12.2 19.8 7.6 7.4 37.8 40.1 18.5 30.5 22.5 18.3 46.0 34.7 23.0 39.1 27.8 77.9 21.9 51.4 28.5 23.6 54.0 31.6 60.6 41.9 61.3 35.2 40.6 49.7 17.4 58.2 34.6 40.2 22.4 24.1 30.2 39.4 45.0 11.3 29.1 32.7 69.7 27.3 35.7 27.4 39.9 38.1 52.0 68.7 43.1 33.3 45.2 54.8 29.8 31.7 32.7 24.0 26.1 32.4 57.8 29.7 22.9 22.4 21.2 44.2 48.0 40.1 97.9 21.6 33.1 78.1 36.3 59.1 62.1 0.9 12.6 2.8 12.2 18.1 19.1 19.2 13.8 14.4 16.8 14.5 16.0 14.6 2.4 15.0 13.0 11.8 16.0 21.3 6.4 8.0 7.0 11.8 12.0 7.3 6.7 6.9 6.8 6.7 6.9 7.4 23.7 16.0 13.2 3.3 29.9 83.2 62.8 29.5 25.6 22.7 18.6 18.4 11.9 18.6 36.2 7.3 12.5 39.5 20.2 7.9 19.6 36.7 33.5 28.7 37.7 25.5 17.3 21.4 10.6 29.8 43.5 28.3 9.7 20.9 31.6 13.6 12.5 15.8 26.0 18.5 9.0 12.1 30.5 10.4 38.7 7.7 12.5 20.7 12.4 4.7 18.9 21.0 14.4 7.1 10.4 29.1 5.8 16.6 27.8 56.6 4.6 34.7 28.6 51.3 6.6 40.4 29.6 28.9 41.7 21.0 56.1 47.6 25.7 20.5 20.2 37.6 PNRC1 "B4-2, PROL2, PRR2" ENSG00000146278 "Proline rich nuclear receptor coactivator 1" Q12796 6 89080751-89085160 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 1848.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 212.8;hTCEpi: 234.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029839, HPA066513" Approved Approved Nucleoplasm,Nucleoli NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Nucleoli" "HPA029839: AB_10601247, HPA066513: AB_2685684" "unprognostic (9.02e-3)" "unprognostic (7.65e-2)" "unprognostic (3.01e-2)" "unprognostic (2.31e-2)" "unprognostic (6.10e-2)" "unprognostic (1.52e-1)" "unprognostic (2.28e-1)" "unprognostic (1.78e-1)" "unprognostic (5.20e-2)" "unprognostic (5.28e-3)" "unprognostic (1.96e-2)" "unprognostic (6.29e-2)" "prognostic unfavorable (6.88e-6)" "unprognostic (8.63e-3)" "unprognostic (2.05e-1)" "unprognostic (1.03e-1)" "unprognostic (5.09e-2)" 232.7 171.7 61.6 145.9 66.3 368.1 135.4 84.0 67.5 93.8 47.9 158.4 70.2 100.6 80.4 91.4 204.4 139.3 132.5 58.3 74.2 103.5 318.1 159.6 134.1 87.7 65.7 222.5 89.2 86.8 78.5 122.6 73.0 95.0 77.5 129.8 91.9 84.3 460.6 147.5 94.3 130.3 69.5 139.6 104.6 50.1 57.4 165.9 105.6 163.4 111.2 141.4 98.5 80.4 12.1 12.0 25.3 42.4 96.7 166.6 16.9 16.0 110.6 29.5 69.0 10.2 34.5 25.9 71.2 19.4 116.3 40.5 13.3 23.9 45.6 31.8 36.3 4.7 69.8 31.9 212.8 25.0 57.9 117.6 234.4 19.6 90.1 107.9 49.4 30.3 4.1 81.0 33.3 11.5 6.8 124.7 7.0 13.9 23.1 29.1 30.0 21.5 70.2 21.1 15.7 42.2 40.3 56.3 44.0 73.6 27.9 119.4 44.8 23.1 13.2 16.2 5.9 118.3 64.0 9.0 46.3 20.6 14.9 32.8 17.3 103.8 18.3 19.0 19.0 20.7 22.1 19.7 11.3 23.0 24.9 25.9 100.9 19.2 17.9 18.7 19.0 10.5 61.6 66.3 84.0 67.5 58.3 74.2 87.7 65.7 73.0 69.5 57.4 80.4 405.7 141.1 149.8 36.2 747.6 968.9 776.8 98.9 1286.2 130.6 412.5 381.5 188.6 230.2 65.2 90.1 50.1 235.8 662.8 158.1 234.8 203.5 103.4 528.4 655.3 356.1 248.0 284.1 10.0 238.2 78.6 720.1 225.8 955.1 164.6 153.2 238.5 207.6 229.4 72.3 15.5 200.7 34.6 452.6 1848.0 41.5 481.9 898.3 439.4 39.4 763.5 403.3 440.8 20.1 41.5 143.0 184.6 377.3 530.6 738.5 211.1 319.2 61.5 134.8 420.7 731.3 725.6 51.9 64.6 840.2 1250.8 274.5 735.8 214.3 136.9 472.8 POC1A "DKFZP434C245, WDR51A" ENSG00000164087 "POC1 centriolar protein A" Q8NBT0 3 52075226-52154690 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Dwarfism, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 12.8;testis: 17.6" "Cell type enhanced" "Detected in many" "Early spermatids: 47.9;Extravillous trophoblasts: 33.8;Late spermatids: 73.4;Spermatocytes: 40.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040600 Approved NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA040600: AB_10672837" "unprognostic (2.68e-1)" "unprognostic (7.17e-2)" "prognostic favorable (1.78e-4)" "unprognostic (5.08e-2)" "unprognostic (3.61e-1)" "unprognostic (1.31e-1)" "unprognostic (1.02e-3)" "unprognostic (2.41e-2)" "unprognostic (7.23e-3)" "unprognostic (1.79e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (3.89e-2)" "prognostic unfavorable (9.43e-7)" "unprognostic (9.90e-3)" "unprognostic (1.96e-1)" "unprognostic (3.62e-2)" "unprognostic (2.32e-2)" 1.4 4.1 1.5 4.0 1.5 11.1 2.2 1.4 1.8 1.5 1.1 5.9 4.8 1.0 1.0 4.7 1.7 1.1 1.4 1.7 1.6 2.1 5.2 1.9 5.4 1.9 1.6 0.7 0.9 1.1 0.7 4.1 1.8 1.3 6.0 0.4 1.3 1.0 1.5 2.6 4.0 2.9 1.5 2.8 2.8 17.6 1.6 12.8 1.0 1.0 7.0 2.0 1.8 1.8 30.1 25.2 25.0 33.5 5.1 6.5 33.9 30.0 28.7 62.8 48.7 22.1 31.0 31.3 8.8 23.9 48.6 18.3 38.0 33.9 45.3 26.0 16.0 21.4 26.3 23.9 1.4 24.5 13.0 3.6 7.3 49.6 25.9 8.7 29.0 46.2 18.8 32.9 37.5 23.8 45.6 44.2 19.1 33.7 41.0 19.6 19.7 30.0 14.2 21.0 11.6 16.7 24.0 23.7 18.3 26.0 29.2 45.7 9.7 28.6 27.6 46.3 49.3 27.8 49.1 26.6 19.2 42.6 29.1 0.0 1.6 0.0 1.2 2.2 0.1 0.9 0.8 0.4 1.9 0.5 0.7 0.4 0.5 1.4 1.6 1.9 2.6 1.1 1.5 1.5 1.4 1.8 1.7 1.6 1.9 1.6 1.8 1.5 1.6 1.8 0.9 0.0 1.3 0.3 2.5 1.7 1.6 4.7 0.0 0.7 2.1 2.2 0.7 0.0 1.4 1.8 0.0 21.8 0.9 4.4 0.0 1.8 47.9 4.5 1.0 2.9 1.8 15.6 2.3 3.0 33.8 3.4 2.0 1.5 0.0 11.3 1.8 4.2 12.9 1.7 1.4 5.4 0.0 2.6 3.4 73.4 1.2 2.6 1.8 1.9 2.7 0.8 1.0 0.0 2.7 2.1 2.2 0.4 12.9 1.3 3.0 3.2 4.2 0.0 0.0 1.1 3.4 40.1 21.2 4.9 1.8 7.5 1.6 4.4 8.4 2.1 POC5 "C5orf37, FLJ35779, hPOC5, MGC120442, MGC120443, MGC120444" ENSG00000152359 "POC5 centriolar protein" Q8NA72 5 75674124-75717448 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 102.7;Late spermatids: 53.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037509, HPA037510, HPA061521" Approved Enhanced Nucleoplasm NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "HPA037509: AB_2797227, HPA037510: AB_10672349, HPA061521: AB_2797263" "unprognostic (1.33e-1)" "unprognostic (4.35e-2)" "unprognostic (1.97e-1)" "unprognostic (8.62e-2)" "unprognostic (1.26e-1)" "unprognostic (2.08e-2)" "prognostic unfavorable (1.60e-7)" "unprognostic (1.99e-1)" "unprognostic (6.38e-2)" "unprognostic (2.97e-1)" "unprognostic (4.62e-2)" "unprognostic (6.81e-2)" "prognostic unfavorable (6.74e-5)" "unprognostic (1.02e-1)" "unprognostic (1.22e-1)" "unprognostic (1.28e-1)" "prognostic favorable (1.09e-4)" 5.8 6.1 5.3 6.1 7.6 10.2 9.5 6.9 8.1 7.6 4.3 5.1 4.6 7.6 8.3 3.8 8.9 4.4 3.8 5.2 5.8 5.2 4.5 6.0 11.4 6.8 6.5 11.2 5.1 5.7 3.3 5.9 6.9 6.9 6.3 29.2 4.3 5.2 3.8 6.0 5.9 7.3 5.9 9.7 5.5 20.1 6.1 14.3 5.7 3.5 11.0 5.6 5.5 10.5 16.1 12.4 20.5 20.4 8.7 7.0 15.0 14.9 8.9 25.9 19.4 18.3 14.3 21.5 27.9 8.4 34.8 14.8 18.3 14.8 19.3 23.3 12.7 14.1 9.3 10.2 11.7 16.2 26.3 7.8 14.3 19.6 32.4 8.7 10.5 21.6 13.8 38.1 12.2 19.1 26.3 20.5 8.9 3.6 10.9 16.5 17.0 25.8 11.9 7.8 16.1 17.7 14.0 7.6 15.7 10.3 14.5 18.5 4.5 8.7 19.2 15.3 30.5 23.4 53.1 31.6 13.2 21.3 21.1 8.1 10.0 23.1 14.6 11.2 12.9 15.1 14.5 15.5 15.2 18.0 14.8 14.4 10.0 18.5 9.0 17.1 21.5 8.7 5.3 7.6 6.9 8.1 5.2 5.8 6.8 6.5 6.9 5.9 6.1 10.5 5.9 6.4 11.1 6.2 8.3 2.7 3.0 8.2 5.2 12.3 5.2 6.2 3.9 8.6 6.3 7.3 12.5 7.4 12.2 3.6 9.8 7.7 102.7 12.3 8.4 5.8 4.9 13.5 18.4 6.9 7.7 6.1 6.1 5.7 2.5 8.1 6.1 3.6 6.3 10.1 9.4 4.0 10.2 5.4 4.8 53.3 6.2 6.0 3.6 14.0 4.0 5.9 10.3 9.0 32.1 5.5 2.5 7.2 10.5 2.5 3.2 5.1 19.9 39.0 6.6 3.8 6.0 36.8 15.7 6.4 2.8 4.1 10.8 9.6 5.5 1.7 POLA2 FLJ21662 ENSG00000014138 "DNA polymerase alpha 2, accessory subunit" Q14181 11 65261920-65305589 "Metabolic proteins, Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 23.2;Spermatocytes: 23.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA037570 Supported Supported Nucleoplasm,Cytosol NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA037570: AB_10672280" "unprognostic (2.28e-1)" "prognostic favorable (4.61e-4)" "unprognostic (1.67e-2)" "unprognostic (7.44e-2)" "unprognostic (5.20e-2)" "unprognostic (3.18e-2)" "prognostic unfavorable (2.11e-6)" "unprognostic (1.14e-1)" "unprognostic (2.87e-2)" "unprognostic (1.15e-2)" "unprognostic (4.05e-2)" "unprognostic (1.83e-1)" "prognostic unfavorable (4.09e-8)" "unprognostic (1.60e-3)" "unprognostic (8.26e-2)" "unprognostic (8.16e-2)" "unprognostic (6.25e-3)" 3.3 2.6 1.9 5.3 2.9 6.9 3.5 4.8 3.3 4.5 1.7 5.3 3.6 5.0 3.3 4.5 3.8 1.8 2.9 1.9 1.5 3.5 3.7 3.5 10.0 4.5 2.8 5.1 3.3 3.2 1.9 2.1 3.7 3.0 4.9 3.6 4.2 3.1 3.1 5.1 4.2 4.1 3.1 5.7 3.8 5.2 2.6 15.9 3.3 3.4 13.2 3.2 3.2 7.0 32.6 21.9 47.3 20.4 3.7 3.6 19.5 25.6 15.9 64.4 43.3 6.9 24.0 48.1 20.4 11.0 35.5 18.9 38.8 25.1 61.1 21.3 14.7 32.4 39.4 10.4 0.9 33.5 25.6 3.7 2.9 47.4 8.5 10.3 14.6 20.2 30.2 25.3 44.4 34.9 62.6 13.2 38.6 16.1 16.2 33.4 29.9 40.7 14.1 21.8 32.5 18.1 14.9 15.9 7.9 29.7 28.6 14.1 3.9 25.4 18.7 19.8 16.0 12.0 14.7 45.0 14.9 18.8 33.7 10.0 5.2 2.3 3.8 3.2 4.5 3.9 4.2 4.2 7.4 3.9 3.5 3.1 1.4 3.8 1.7 5.9 4.6 5.3 1.9 2.9 4.8 3.3 1.9 1.5 4.5 2.8 3.7 3.1 2.6 7.0 2.6 0.0 3.4 1.0 5.1 1.7 4.2 5.7 2.2 2.2 3.0 2.3 2.9 7.2 3.7 5.5 2.1 15.6 4.3 3.0 3.9 5.3 2.7 1.8 2.9 3.7 3.0 23.2 4.3 3.4 19.0 7.7 5.6 2.5 0.0 11.0 5.3 2.1 9.7 3.3 3.6 3.5 2.0 2.8 3.7 4.0 7.5 5.3 0.0 12.2 8.0 2.2 5.2 1.5 8.7 4.9 2.2 7.5 10.4 3.4 1.7 2.0 3.2 5.4 6.6 19.6 5.0 23.7 17.7 4.3 1.4 7.3 5.5 4.0 6.3 3.7 POLD3 "KIAA0039, P66, P68, PPP1R128" ENSG00000077514 "DNA polymerase delta 3, accessory subunit" Q15054 11 74493851-74669117 "Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA excision, DNA repair, DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA058846 Enhanced Supported Nucleoplasm NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA058846: AB_2683833" "unprognostic (3.68e-1)" "unprognostic (3.22e-2)" "unprognostic (2.05e-3)" "unprognostic (3.28e-1)" "unprognostic (1.74e-1)" "unprognostic (3.49e-1)" "prognostic unfavorable (9.17e-4)" "unprognostic (1.08e-1)" "prognostic unfavorable (5.48e-4)" "unprognostic (3.99e-3)" "unprognostic (1.54e-3)" "unprognostic (9.21e-3)" "prognostic unfavorable (7.90e-6)" "unprognostic (7.92e-3)" "unprognostic (2.65e-1)" "unprognostic (9.11e-2)" "unprognostic (1.23e-1)" 7.9 6.2 6.1 14.6 6.0 10.1 11.1 6.0 7.3 10.6 7.6 17.2 15.7 16.5 12.0 12.9 16.3 14.9 8.9 5.9 6.1 44.5 7.1 11.5 14.5 4.9 5.6 16.0 11.4 7.8 4.6 11.5 5.6 8.3 17.9 14.9 6.8 10.1 7.7 11.6 14.4 15.3 5.1 11.4 15.4 19.6 5.5 15.7 15.0 12.5 15.2 12.7 7.5 7.4 32.2 28.6 43.6 29.8 13.2 22.5 30.9 42.7 23.9 43.7 37.0 37.8 40.8 45.7 30.9 20.5 25.3 41.2 36.3 28.0 54.6 34.5 23.3 29.1 44.3 12.8 9.5 56.4 25.3 10.0 17.3 51.1 27.3 13.8 17.1 39.8 26.7 35.5 25.6 25.3 63.4 25.3 26.4 95.3 29.1 60.0 109.4 37.9 20.2 30.6 29.0 19.5 50.7 25.3 49.7 26.2 29.5 35.7 16.4 42.9 30.8 48.8 34.2 24.8 56.6 102.4 24.5 35.1 33.2 7.3 22.6 15.9 9.2 18.5 9.1 10.1 11.7 8.2 17.7 8.0 11.6 9.6 19.4 10.8 19.0 5.2 13.7 13.0 6.1 6.0 6.0 7.3 5.9 6.1 4.9 5.6 5.6 5.1 5.5 7.4 14.8 12.8 20.0 13.1 9.7 5.9 7.0 11.4 12.5 12.3 10.5 12.8 7.8 7.2 17.7 9.2 8.4 19.7 11.1 17.9 5.9 17.2 28.3 24.8 17.1 14.2 5.4 24.2 20.1 32.1 26.7 13.1 16.8 14.4 19.0 20.9 8.2 4.9 15.6 23.5 15.3 12.7 12.2 12.9 7.2 23.1 12.5 16.9 3.6 15.0 25.3 15.3 9.2 6.6 18.7 17.4 13.4 8.6 11.4 11.4 10.7 39.1 45.2 19.1 6.6 13.7 12.4 60.3 37.7 11.2 5.4 13.0 11.8 10.0 19.9 10.5 POLH "RAD30A, XP-V" ENSG00000170734 "DNA polymerase eta" Q9Y253 6 43576185-43620523 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Mutator protein, Nucleotidyltransferase, Transferase" "Disease variant, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 25.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 91.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006721, HPA026762" Approved Enhanced Nucleoplasm NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA006721: AB_1847785, HPA026762: AB_10601248" "unprognostic (1.79e-1)" "unprognostic (7.29e-2)" "unprognostic (2.25e-1)" "unprognostic (7.28e-2)" "unprognostic (3.61e-1)" "unprognostic (5.11e-3)" "unprognostic (9.68e-2)" "unprognostic (1.40e-1)" "unprognostic (3.18e-1)" "unprognostic (7.75e-2)" "unprognostic (4.11e-3)" "unprognostic (2.24e-1)" "unprognostic (9.50e-2)" "unprognostic (6.73e-2)" "unprognostic (8.77e-2)" "unprognostic (7.91e-2)" "unprognostic (6.02e-2)" 5.0 3.8 2.3 6.9 2.7 4.2 4.8 5.1 2.9 5.9 5.3 7.0 4.6 4.2 3.6 5.5 5.5 4.3 3.7 2.2 2.2 4.7 5.6 5.7 12.9 2.7 2.2 4.7 5.4 3.7 3.2 4.0 2.7 4.7 7.2 7.4 4.0 3.8 8.5 8.5 4.4 6.3 1.8 5.6 4.6 10.6 2.5 12.9 6.8 4.7 14.2 4.8 4.3 3.6 46.7 9.7 13.5 19.9 17.6 29.1 33.0 48.6 13.9 26.2 29.2 12.0 7.9 48.9 12.0 17.6 7.6 11.4 13.1 28.6 31.5 25.9 10.0 15.3 31.6 35.5 13.4 26.8 19.2 19.5 33.4 21.5 11.3 10.6 24.3 14.5 24.0 29.6 33.0 15.0 23.9 6.4 4.2 33.2 7.2 25.1 14.3 11.8 9.9 34.6 15.1 5.4 14.5 12.9 7.3 15.4 17.9 10.8 36.2 23.6 24.4 12.2 25.2 28.0 21.3 91.1 11.8 14.5 27.3 4.1 1.7 2.7 4.2 1.6 3.8 5.0 3.5 3.1 1.3 4.9 2.8 3.0 1.7 4.2 1.6 2.6 4.6 2.0 2.3 2.7 5.1 2.9 2.2 2.2 2.7 2.2 2.7 1.8 2.5 3.6 3.1 12.8 8.2 12.1 15.1 4.7 3.2 4.8 19.4 6.3 3.4 3.3 2.3 5.7 6.5 3.7 10.4 2.4 5.2 6.3 5.9 2.1 11.4 10.2 4.8 2.8 5.4 5.7 14.8 0.9 2.8 5.3 8.2 9.0 0.0 6.1 1.4 2.4 1.7 0.0 15.3 2.2 4.1 2.2 2.2 7.3 3.4 3.0 1.8 6.5 3.2 2.6 2.1 10.1 13.4 1.9 4.5 3.0 12.7 2.2 3.1 2.3 5.4 9.4 0.0 7.0 5.0 25.9 6.7 13.0 3.0 1.9 8.8 5.6 3.0 2.3 POLQ POLH ENSG00000051341 "DNA polymerase theta" O75417 3 121431427-121546641 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;lymphoid tissue: 4.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 16.4;Excitatory neurons: 9.5;Granulosa cells: 12.6;Inhibitory neurons: 7.8;Plasma cells: 12.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 2.5" HPA053359 Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus, Cytosol" "HPA053359: " "unprognostic (1.59e-1)" "unprognostic (4.18e-2)" "unprognostic (2.66e-2)" "prognostic unfavorable (5.46e-5)" "unprognostic (2.70e-1)" "unprognostic (6.23e-3)" "unprognostic (3.09e-5)" "unprognostic (8.55e-3)" "unprognostic (1.09e-4)" "unprognostic (2.86e-1)" "unprognostic (5.59e-5)" "unprognostic (2.06e-3)" "unprognostic (0.00e+0)" "prognostic favorable (1.04e-4)" "unprognostic (1.76e-1)" "unprognostic (6.01e-2)" "unprognostic (5.76e-2)" 0.1 0.2 0.0 1.6 0.1 6.0 0.4 1.0 0.2 0.2 0.0 1.2 1.2 0.2 0.0 2.0 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.2 2.8 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 2.0 0.0 0.3 0.0 0.0 1.4 0.9 0.4 0.0 0.8 0.5 2.2 0.0 4.5 0.0 0.0 2.3 0.3 0.5 0.0 18.2 12.1 10.2 7.2 0.9 1.2 9.2 8.5 3.2 9.7 12.9 9.8 6.6 21.5 3.7 4.6 11.7 14.0 12.2 5.4 16.4 6.3 6.7 13.8 8.0 6.1 0.1 15.1 12.1 0.2 0.4 8.9 5.4 1.7 4.9 7.9 9.3 15.9 10.3 7.1 13.7 8.8 9.7 5.5 5.9 11.4 12.2 7.6 3.1 10.3 5.5 5.0 9.8 5.2 3.4 8.8 4.8 14.8 3.8 8.6 11.2 3.4 11.1 8.0 6.9 21.8 4.1 11.0 6.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 1.6 0.7 0.9 0.5 0.6 0.0 0.9 0.6 0.6 1.6 0.0 2.0 0.0 0.0 3.1 0.6 1.6 0.0 0.1 0.4 0.9 1.0 0.5 0.0 16.4 9.5 0.0 3.3 1.2 4.6 1.0 0.0 12.6 0.0 0.2 2.3 0.0 7.8 1.6 2.0 1.3 1.2 0.7 0.3 1.7 0.0 1.0 0.6 0.4 0.0 1.5 1.3 0.2 1.2 0.0 12.2 0.5 0.2 0.1 2.4 0.2 0.0 0.1 1.0 6.8 3.4 4.9 0.1 0.3 1.8 0.9 3.2 0.8 POLR2A "POLR2, POLRA, RPB1" ENSG00000181222 "RNA polymerase II subunit A" 17 7484366-7514616 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.4;lymphoid tissue: 1.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SCLC-21H: 3.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012226, CAB016388, HPA021563, HPA053012" Enhanced Nucleoplasm,Cytosol NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "CAB012226: AB_304749, CAB016388: AB_677353, HPA021563: AB_1855526, HPA053012: AB_2682017" "unprognostic (2.03e-1)" "unprognostic (1.32e-1)" "unprognostic (1.58e-1)" "unprognostic (2.40e-1)" "unprognostic (1.71e-1)" "unprognostic (5.43e-2)" "unprognostic (8.77e-3)" "unprognostic (1.48e-1)" "unprognostic (5.19e-3)" "unprognostic (1.81e-1)" "unprognostic (1.52e-1)" "unprognostic (3.70e-2)" "unprognostic (1.01e-3)" "unprognostic (1.25e-1)" "unprognostic (2.30e-2)" "unprognostic (1.49e-1)" "unprognostic (4.70e-2)" 0.1 0.7 0.4 1.6 0.2 0.2 0.1 0.3 1.9 0.0 0.8 0.1 0.5 0.1 0.0 0.0 0.2 0.1 0.1 0.7 0.4 0.1 0.0 0.2 0.2 2.4 0.7 0.1 0.0 0.1 0.2 1.1 0.2 0.2 0.3 0.0 0.0 0.5 0.1 0.4 0.0 0.4 0.2 0.0 0.7 1.1 0.2 0.0 0.1 0.0 0.0 1.6 1.0 1.7 0.5 1.5 0.4 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.6 0.4 0.4 0.0 0.6 1.0 2.1 0.0 0.0 0.3 0.0 0.5 0.0 0.9 0.0 1.6 2.9 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.3 1.0 0.4 2.1 0.0 0.0 2.5 2.3 1.0 0.0 2.7 3.5 2.8 1.2 0.8 0.0 0.0 0.8 1.6 0.0 1.0 0.5 1.1 2.0 0.4 0.2 1.6 1.1 0.8 1.0 0.0 2.2 0.8 2.0 0.9 2.5 1.1 0.3 0.8 2.2 0.5 1.3 1.0 0.0 2.0 4.2 0.0 3.2 10.1 0.4 0.2 0.3 1.9 0.7 0.4 2.4 0.7 1.1 0.4 1.1 1.6 124.2 22.4 41.6 13.4 68.0 42.8 40.7 33.8 64.3 90.4 56.5 187.1 26.9 38.6 30.3 23.9 110.5 35.9 153.5 55.0 3.9 27.0 25.0 74.9 64.4 57.7 76.7 43.3 18.1 30.2 28.7 53.3 103.0 67.3 42.5 46.0 40.4 29.9 45.4 55.5 14.9 43.9 26.4 42.1 38.3 7.4 37.0 65.7 37.4 19.7 38.2 27.3 26.8 17.6 17.8 32.0 35.9 41.8 62.0 27.9 42.5 13.2 38.4 90.5 6.6 94.4 53.9 58.5 120.2 73.8 41.2 53.8 89.2 49.8 32.6 30.8 PPARGC1B "PERC, PGC1B" ENSG00000155846 "PPARG coactivator 1 beta" Q86YN6 5 149730298-149855022 "Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 12.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 111.8;Cone photoreceptor cells: 135.5;Rod photoreceptor cells: 72.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 9.7" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA050543 Supported Nucleoplasm,Cytosol NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 15: RT4 - Unknown function" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm Cytosol "HPA050543: AB_2681165" "unprognostic (2.86e-1)" "unprognostic (1.07e-2)" "unprognostic (5.09e-3)" "unprognostic (1.13e-3)" "unprognostic (2.63e-1)" "unprognostic (2.00e-3)" "unprognostic (4.51e-3)" "unprognostic (6.55e-2)" "unprognostic (9.14e-3)" "unprognostic (2.65e-2)" "unprognostic (1.83e-1)" "unprognostic (1.21e-1)" "unprognostic (9.01e-6)" "unprognostic (8.45e-2)" "unprognostic (5.09e-2)" "unprognostic (1.51e-1)" "unprognostic (2.77e-3)" 2.2 0.9 2.1 2.4 2.2 2.0 1.4 9.7 3.1 1.4 0.0 7.0 7.0 2.1 1.1 4.1 2.2 1.2 6.3 1.6 0.4 0.8 1.6 3.6 1.4 1.9 0.2 1.3 1.0 4.4 0.6 1.5 2.0 1.8 6.0 12.4 1.4 3.3 6.2 3.3 6.4 2.8 0.4 2.1 3.8 0.8 0.3 0.9 0.4 2.5 1.8 3.7 2.6 0.5 0.5 1.9 0.7 4.5 1.8 0.6 7.3 0.3 0.0 0.5 0.7 8.5 1.8 9.2 1.3 0.0 2.1 5.5 6.9 3.5 0.6 0.5 5.9 8.6 3.6 1.8 0.5 12.0 3.2 0.9 4.6 1.8 3.0 0.2 1.0 4.0 6.0 2.9 0.4 2.3 4.4 5.4 2.9 2.6 4.8 8.3 5.0 5.1 1.4 11.2 2.4 0.5 1.2 9.8 1.5 1.3 2.5 3.9 1.3 1.0 1.6 3.6 1.8 3.6 2.8 5.3 2.2 7.4 0.9 0.5 0.9 0.1 0.1 1.7 0.3 0.8 0.1 0.1 1.1 0.3 0.2 0.2 0.6 0.3 3.1 0.1 0.1 0.3 2.1 2.2 9.7 3.1 1.6 0.4 1.9 0.2 2.0 0.4 0.3 0.5 6.1 0.0 1.1 1.6 3.0 5.1 3.9 17.9 12.0 111.8 2.5 3.2 22.3 1.5 7.4 1.8 135.5 1.8 0.7 15.4 1.9 0.5 0.3 1.7 4.1 5.4 5.4 5.7 29.2 0.8 1.6 2.7 18.8 2.5 1.3 2.1 4.2 3.5 7.6 8.4 26.2 10.3 0.0 12.5 4.7 0.2 1.5 12.1 3.6 12.2 6.1 4.0 2.1 12.1 0.9 0.5 6.7 0.4 5.5 5.1 19.6 3.0 2.9 72.0 6.6 3.0 8.9 0.2 3.2 23.1 10.7 4.9 2.0 2.1 24.9 6.1 PPP1R13L "IASPP, RAI" ENSG00000104881 "Protein phosphatase 1 regulatory subunit 13 like" Q8WUF5 19 45379638-45406349 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 179.4;heart muscle: 139.4;skin 1: 219.8" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 85.6;Granulosa cells: 118.3;Syncytiotrophoblasts: 128.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HBEC3-KT: 130.1;hTCEpi: 189.0;hTERT-HME1: 131.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005016, HPA041231, HPA059883" Approved Enhanced Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" Cytosol "CAB005016: AB_2168576, HPA041231: AB_2677376, HPA059883: AB_2684151" "unprognostic (1.87e-1)" "unprognostic (1.78e-1)" "unprognostic (7.46e-2)" "unprognostic (2.92e-1)" "unprognostic (3.74e-1)" "unprognostic (2.06e-2)" "unprognostic (1.31e-3)" "prognostic unfavorable (3.39e-5)" "unprognostic (1.77e-1)" "prognostic unfavorable (5.40e-4)" "unprognostic (2.52e-3)" "unprognostic (1.92e-2)" "unprognostic (1.55e-3)" "unprognostic (1.34e-1)" "unprognostic (7.69e-2)" "unprognostic (8.87e-2)" "unprognostic (1.02e-1)" 20.4 20.1 11.7 2.9 11.7 0.6 29.6 11.5 14.0 44.9 9.5 11.1 5.0 8.2 15.2 179.4 9.6 6.0 139.4 10.8 14.3 24.8 12.6 20.3 2.6 11.9 11.1 8.8 31.5 12.2 11.8 26.6 11.7 30.8 6.8 13.6 55.6 13.3 5.8 219.8 9.1 5.4 10.0 6.4 12.0 3.1 12.7 4.0 17.7 4.4 18.8 23.6 84.9 12.4 72.3 10.7 4.6 3.8 4.7 2.9 61.5 14.5 2.5 17.5 24.3 23.1 70.6 9.5 5.9 11.9 36.5 97.2 4.0 130.1 16.0 24.0 5.9 1.4 36.3 8.7 10.0 1.0 3.4 4.0 189.0 27.9 131.9 79.2 33.2 7.9 8.1 3.6 1.2 64.7 1.8 1.9 5.3 36.9 18.3 7.4 5.6 1.7 22.9 95.0 2.4 7.6 64.5 68.4 1.6 30.0 58.2 1.9 46.3 23.1 60.9 1.8 76.2 35.1 42.1 6.5 3.3 2.9 5.6 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.2 0.0 11.7 11.7 11.5 14.0 10.8 14.3 11.9 11.1 11.7 10.0 12.7 12.4 14.3 35.3 13.0 9.4 2.0 68.7 85.6 38.4 67.2 1.7 21.9 28.6 38.8 20.0 27.8 20.2 10.4 83.2 2.5 17.8 5.9 34.9 0.7 8.7 3.0 13.4 7.2 10.1 0.8 15.8 37.7 5.6 8.6 17.1 4.5 118.3 11.7 2.5 7.6 0.0 0.9 6.9 14.2 1.6 5.0 0.5 5.9 2.2 12.4 9.4 1.9 2.4 2.1 2.5 1.6 50.4 17.2 12.4 6.1 44.2 22.6 3.9 16.3 26.8 6.6 8.4 14.1 2.7 2.1 81.2 71.0 128.5 2.5 2.8 9.0 63.4 PRC1 ASE1 ENSG00000198901 "Protein regulator of cytokinesis 1" O43663 15 90966040-90995629 "Predicted intracellular proteins" "Cell cycle, Cell division" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 89.9;testis: 55.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 142.9;Extravillous trophoblasts: 68.3;Spermatocytes: 136.4;Spermatogonia: 74.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 34.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 34.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034521, HPA048816" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Cytokinetic bridge,Midbody" Yes Yes "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Microtubules, Cytokinetic bridge, Midbody" Nucleoplasm "HPA034521: AB_10670169, HPA048816: " "unprognostic (1.14e-1)" "unprognostic (3.98e-2)" "unprognostic (9.21e-2)" "unprognostic (1.75e-3)" "unprognostic (2.39e-1)" "unprognostic (3.43e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.24e-3)" "unprognostic (3.86e-3)" "unprognostic (1.65e-2)" "prognostic unfavorable (2.76e-5)" "unprognostic (2.49e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.09e-2)" "unprognostic (1.79e-1)" "unprognostic (7.90e-2)" "unprognostic (3.92e-2)" 7.4 6.2 6.4 10.0 6.1 89.9 6.4 10.3 8.4 8.1 5.0 16.3 10.6 5.7 2.3 37.6 6.0 3.0 6.9 5.6 4.9 5.6 4.8 9.0 16.9 4.8 5.2 8.1 8.9 2.6 3.6 15.3 5.2 4.9 16.5 4.9 9.5 1.5 4.1 20.1 13.0 9.4 4.9 12.5 11.7 55.0 4.2 43.0 4.3 2.3 24.9 4.8 13.7 5.6 167.9 199.9 164.8 113.6 16.8 28.7 87.5 237.8 139.3 257.2 195.3 134.6 158.5 65.5 91.4 151.9 156.9 220.9 188.8 101.2 240.6 118.7 206.4 135.6 263.5 123.5 4.1 71.4 109.0 7.7 12.8 145.8 146.9 56.6 146.4 100.5 114.0 132.4 241.1 144.4 66.9 98.5 66.6 216.4 84.9 69.7 205.1 86.3 115.3 123.6 151.2 118.9 225.4 121.9 82.7 112.3 149.1 127.1 91.2 168.2 146.0 140.5 345.1 43.5 127.7 80.0 74.5 162.0 265.3 34.4 0.6 2.9 0.6 0.1 0.4 1.1 1.3 1.3 2.4 0.5 1.2 0.4 0.4 3.0 0.3 2.6 8.0 1.0 6.4 6.1 10.3 8.4 5.6 4.9 4.8 5.2 5.2 4.9 4.2 5.6 2.5 0.0 3.1 1.3 6.8 16.6 6.6 8.0 2.2 6.4 3.4 4.3 3.2 0.0 7.6 3.7 0.0 45.5 2.8 16.5 0.0 3.2 41.5 4.5 4.0 4.7 5.4 142.9 5.0 2.9 68.3 7.2 16.3 6.8 8.9 13.2 9.3 2.1 21.5 3.3 5.2 17.0 10.2 8.7 15.0 15.4 3.7 5.2 3.6 1.9 5.5 3.8 4.1 2.0 1.7 2.3 3.2 1.9 17.5 5.9 2.0 0.1 3.2 4.6 6.6 7.4 10.9 136.4 74.2 38.0 14.2 14.6 6.8 0.4 24.1 6.7 PRIM1 ENSG00000198056 "DNA primase subunit 1" P49642 12 56731296-56752374 "Predicted intracellular proteins" "DNA replication, Transcription" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 28.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 56.4;Spermatocytes: 118.2;Spermatogonia: 107.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040010 Uncertain NA Yes "Cluster 24: B-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA040010: AB_10805599" "unprognostic (3.04e-3)" "unprognostic (1.67e-2)" "unprognostic (2.12e-2)" "unprognostic (1.51e-2)" "unprognostic (4.63e-2)" "unprognostic (3.61e-2)" "prognostic unfavorable (2.40e-8)" "unprognostic (4.68e-2)" "unprognostic (2.73e-3)" "unprognostic (1.82e-3)" "unprognostic (1.56e-1)" "unprognostic (1.82e-1)" "unprognostic (1.98e-3)" "unprognostic (3.94e-1)" "unprognostic (2.16e-1)" "unprognostic (5.35e-2)" "unprognostic (6.53e-2)" 3.7 3.2 2.0 7.0 2.8 28.2 9.9 5.5 2.8 3.7 1.2 7.9 4.5 5.0 4.2 4.4 5.3 2.9 2.3 1.9 2.0 3.0 7.5 4.9 12.3 2.5 2.2 8.9 6.1 6.1 2.1 4.8 2.6 3.6 11.2 8.3 3.9 3.9 4.6 7.8 7.7 5.8 2.0 6.9 5.4 14.4 2.3 18.8 5.0 5.6 14.4 3.8 3.1 4.3 43.0 37.9 52.1 29.2 5.1 9.1 57.8 34.7 28.7 62.1 59.8 42.0 54.4 83.0 27.4 15.8 26.0 40.4 60.3 39.9 68.8 40.7 40.4 106.2 22.6 36.8 1.2 129.3 43.2 4.2 7.2 55.8 22.1 8.8 22.6 92.1 105.5 123.8 35.4 33.6 76.8 54.4 53.5 32.0 47.1 85.0 81.4 70.9 15.0 35.4 51.0 46.0 41.4 20.6 19.9 36.2 67.2 52.8 10.9 32.2 70.7 33.1 46.4 45.1 94.5 45.3 19.4 55.4 40.9 2.5 1.9 4.4 9.1 4.0 9.5 11.3 11.2 8.5 3.9 12.2 14.0 10.7 1.0 6.8 7.1 7.5 10.0 5.3 2.0 2.8 5.5 2.8 1.9 2.0 2.5 2.2 2.6 2.0 2.3 4.3 6.9 6.4 6.8 4.6 10.4 3.8 10.7 10.0 4.6 5.1 7.0 7.2 3.2 2.8 6.1 7.3 6.2 14.9 8.7 2.5 0.0 5.8 6.2 4.1 3.9 6.4 1.2 56.4 5.7 7.2 27.0 5.4 5.6 3.3 3.8 10.0 5.7 4.7 11.8 20.2 10.6 4.6 2.0 8.1 3.1 4.3 7.2 6.5 3.6 2.8 7.9 5.7 8.2 8.0 7.8 2.7 2.2 4.9 9.7 2.2 2.0 2.5 6.0 12.7 13.1 8.2 8.8 118.2 107.2 5.1 4.0 4.5 12.8 3.0 9.4 5.0 PRNP "AltPrP, CD230, CJD, GSS, PRIP, PRP" ENSG00000171867 "Prion protein" P04156 20 4686350-4701590 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cell cycle, Growth arrest" Prion "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 412.6;Basal squamous epithelial cells: 369.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "basophil: 875.9" "Lineage enriched" "Detected in all" 9 "granulocytes: 875.9" "Cell line enhanced" "Detected in many" "WM-115: 1039.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042754, HPA043398" Enhanced Approved "Nuclear membrane,Vesicles,Cytosol" NA Yes 5100000 "Cluster 38: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 41: Macrophages - Immune response" "Nuclear membrane, Cytosol" Vesicles "HPA042754: AB_10964203, HPA043398: AB_2678461" "unprognostic (1.50e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (2.96e-4)" "prognostic unfavorable (4.64e-4)" "prognostic unfavorable (2.52e-4)" "unprognostic (1.94e-2)" "prognostic unfavorable (7.41e-5)" "unprognostic (7.60e-3)" "unprognostic (2.50e-1)" "unprognostic (7.12e-2)" "unprognostic (3.44e-1)" "unprognostic (1.04e-1)" "unprognostic (6.75e-2)" "unprognostic (7.28e-3)" "unprognostic (3.37e-1)" "unprognostic (2.04e-1)" "unprognostic (1.69e-2)" 87.0 92.4 283.8 52.4 308.4 83.7 106.7 255.1 385.9 135.4 415.8 184.2 37.1 125.5 59.1 79.2 79.9 110.1 197.5 315.6 244.8 132.8 79.7 79.2 59.8 262.8 260.8 163.7 41.5 62.8 83.8 66.9 270.1 146.1 70.5 178.6 60.3 148.2 64.0 95.4 47.4 140.8 265.0 75.2 61.6 68.1 302.5 47.9 89.1 74.0 60.0 124.9 83.4 292.8 226.4 141.6 41.7 64.2 329.6 199.9 36.6 363.4 527.6 175.5 177.7 50.0 171.5 40.9 79.2 727.9 391.8 508.8 45.9 498.3 326.2 31.8 39.0 0.2 19.6 193.8 402.0 72.8 16.5 177.5 711.9 701.8 583.9 257.0 152.8 28.6 22.8 142.9 205.1 45.7 28.8 46.2 33.1 99.8 266.4 33.9 110.0 38.3 88.7 40.3 49.2 7.0 98.9 144.3 554.1 56.4 30.2 38.8 224.5 282.9 127.1 158.6 296.1 63.1 129.5 132.9 226.8 51.9 1039.0 875.9 74.1 5.4 67.3 60.9 100.7 25.1 56.9 55.8 62.9 25.6 33.5 40.1 4.6 23.6 50.4 24.6 72.8 72.7 283.8 308.4 255.1 385.9 315.6 244.8 262.8 260.8 270.1 265.0 302.5 292.8 44.9 80.1 45.4 120.2 85.3 412.6 211.8 132.5 369.3 265.4 60.8 103.0 257.7 32.9 68.2 33.1 116.7 7.7 71.8 2.6 11.7 58.1 6.0 14.1 73.2 66.7 29.9 31.8 125.5 14.7 6.3 177.4 14.8 18.2 173.0 25.5 41.0 36.2 63.6 45.4 170.8 5.4 40.7 219.1 200.4 13.6 143.2 126.3 168.9 59.0 54.5 142.4 42.2 95.0 158.8 18.7 4.5 170.0 47.0 120.3 2.2 84.0 38.1 99.0 13.1 73.0 82.3 36.6 4.5 81.6 284.4 14.4 107.2 10.3 8.8 122.6 PRR11 FLJ11029 ENSG00000068489 "Proline rich 11" Q96HE9 17 59155732-59206709 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.1;lymphoid tissue: 20.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 26.3;Extravillous trophoblasts: 22.3;Granulosa cells: 14.4;Kupffer cells: 18.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 9.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA023923, HPA052376" Uncertain Approved "Endoplasmic reticulum" Yes Yes "Cluster 14: Monocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Endoplasmic reticulum" "HPA023923: AB_1855783, HPA052376: AB_2681803" "unprognostic (1.74e-2)" "unprognostic (1.02e-1)" "unprognostic (1.30e-2)" "prognostic unfavorable (1.90e-4)" "unprognostic (2.15e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.35e-7)" "prognostic unfavorable (1.79e-4)" "unprognostic (7.22e-3)" "unprognostic (2.00e-2)" "prognostic unfavorable (6.18e-4)" "unprognostic (2.80e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.56e-2)" "unprognostic (5.21e-2)" "unprognostic (1.84e-1)" "unprognostic (1.55e-3)" 1.3 0.7 1.8 6.5 2.0 18.1 1.8 4.3 2.7 1.2 1.1 4.6 6.5 1.7 0.5 3.8 1.4 1.4 1.0 2.0 1.3 0.6 1.4 2.3 10.3 2.3 1.5 1.4 0.5 0.3 0.0 4.3 2.2 0.8 5.6 1.7 0.6 0.7 1.2 3.1 5.0 3.6 1.1 3.3 2.4 1.8 2.3 20.6 1.3 0.4 12.0 2.0 0.6 3.7 105.3 56.9 84.5 24.8 2.4 16.0 31.7 66.7 41.9 69.1 54.2 68.4 78.7 80.2 65.9 52.7 56.2 40.7 67.0 73.9 145.0 99.3 39.1 86.4 58.8 50.3 0.6 88.7 32.5 4.0 5.3 81.9 109.0 17.1 77.2 57.9 48.6 76.7 72.8 95.2 80.7 26.1 31.9 52.0 82.5 67.3 135.7 45.9 20.0 32.4 34.5 45.4 61.7 18.4 29.2 38.0 54.4 34.1 57.8 146.4 157.3 73.5 117.8 48.8 108.2 73.6 34.5 47.4 150.1 1.7 2.1 2.3 0.6 4.0 0.2 1.1 0.5 0.7 2.6 0.6 0.3 0.5 2.1 0.5 9.5 1.1 1.4 0.8 1.8 2.0 4.3 2.7 2.0 1.3 2.3 1.5 2.2 1.1 2.3 3.7 4.5 0.0 1.7 3.3 3.1 1.9 2.0 1.5 0.0 2.0 0.8 1.5 2.0 1.5 1.6 0.0 0.0 6.2 1.4 2.0 0.0 0.4 0.9 1.4 1.9 3.6 4.9 26.3 1.6 0.5 22.3 2.9 2.6 2.2 2.5 14.4 4.2 0.3 7.8 1.7 1.8 5.0 0.0 18.6 6.3 0.4 0.9 7.8 1.8 2.8 8.4 0.9 4.1 2.0 3.4 0.9 0.7 2.2 9.7 1.1 0.5 0.5 0.6 3.2 0.0 2.9 3.3 2.6 5.1 5.5 1.3 2.1 3.3 1.3 8.4 1.7 PRR13 "DKFZP564J157, FLJ23818" ENSG00000205352 "Proline rich 13" Q9NZ81 12 53441678-53446645 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 884.9;Distal tubular cells: 1365.6;Paneth cells: 858.1;Proximal enterocytes: 1642.7;Proximal tubular cells: 1097.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039396, HPA046219" Uncertain Supported Nucleoplasm NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "HPA039396: AB_2676484, HPA046219: AB_10963936" "unprognostic (1.09e-1)" "prognostic favorable (9.08e-4)" "unprognostic (1.15e-1)" "unprognostic (3.26e-1)" "unprognostic (8.97e-3)" "unprognostic (4.88e-3)" "unprognostic (1.86e-3)" "unprognostic (7.23e-2)" "unprognostic (1.23e-1)" "unprognostic (3.49e-1)" "unprognostic (1.41e-2)" "unprognostic (5.41e-2)" "unprognostic (6.81e-3)" "unprognostic (1.81e-1)" "unprognostic (1.08e-1)" "unprognostic (2.34e-1)" "prognostic favorable (7.55e-4)" 143.8 207.8 110.8 159.2 110.1 279.1 139.2 112.6 147.7 118.9 109.7 316.1 451.6 104.6 110.8 143.4 139.2 147.1 110.6 105.8 147.8 457.9 192.8 164.3 185.3 126.6 132.1 118.8 133.3 76.0 114.6 95.2 126.3 139.6 265.7 44.0 115.5 86.6 131.6 108.7 432.6 91.4 114.3 230.2 247.8 46.4 118.4 139.0 131.8 59.6 190.4 143.7 111.7 117.1 171.7 339.6 82.6 89.4 135.3 185.3 178.4 142.5 213.0 185.6 179.4 623.1 373.6 265.1 453.5 206.8 225.4 146.6 167.8 225.0 217.9 263.1 124.6 382.4 166.4 294.6 340.7 573.2 489.5 232.6 221.2 326.5 223.6 192.6 195.3 166.1 340.1 254.6 285.1 472.5 325.8 563.8 127.5 229.2 230.7 287.6 67.8 273.9 406.2 283.8 72.3 56.5 202.5 276.7 237.2 169.5 394.0 436.2 196.3 117.2 114.0 201.3 138.0 190.7 241.6 386.4 153.3 345.1 220.2 851.3 824.0 1620.1 511.1 941.9 503.0 888.2 563.7 545.8 649.3 855.6 520.6 557.7 2095.7 584.5 1014.6 539.0 824.8 1573.1 110.8 110.1 112.6 147.7 105.8 147.8 126.6 132.1 126.3 114.3 118.4 117.1 66.8 83.3 110.4 6.8 219.1 47.5 147.8 204.8 82.6 11.1 114.3 95.2 26.4 198.8 145.1 187.6 29.2 225.3 159.1 884.9 1365.6 228.0 12.6 182.7 67.1 80.3 169.8 99.2 6.3 253.9 337.7 76.6 263.0 127.4 186.7 53.4 78.1 152.8 355.2 18.5 7.1 346.9 193.3 345.0 174.4 8.7 58.1 266.8 108.5 9.4 384.7 85.3 297.6 4.5 12.9 332.3 858.1 45.9 120.9 174.7 1642.7 1097.6 215.9 20.9 78.9 33.6 67.1 29.7 22.8 107.1 56.0 291.0 212.7 88.4 340.0 193.1 PSMC3IP "GT198, Hop2, HUMGT198A, TBPIP" ENSG00000131470 "PSMC3 interacting protein" Q9P2W1 17 42572310-42577831 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA recombination, Meiosis" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 23.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 113.3;Spermatogonia: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA044439 Enhanced Supported Nucleoplasm NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA044439: AB_10964210" "unprognostic (2.98e-1)" "unprognostic (3.66e-1)" "unprognostic (1.33e-1)" "unprognostic (2.87e-1)" "unprognostic (6.59e-2)" "unprognostic (2.39e-2)" "unprognostic (1.28e-7)" "unprognostic (6.22e-2)" "unprognostic (6.14e-2)" "unprognostic (2.47e-1)" "unprognostic (7.26e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (9.41e-4)" "unprognostic (6.03e-2)" "unprognostic (3.68e-1)" "unprognostic (1.39e-2)" "unprognostic (1.82e-1)" 3.3 1.4 8.3 2.5 8.9 8.2 3.8 8.7 10.3 3.5 7.9 4.2 1.3 3.7 3.8 3.0 6.2 1.4 1.8 7.8 8.5 2.8 0.8 2.3 3.9 9.4 8.9 3.4 2.1 7.6 1.5 4.2 9.2 3.6 3.0 7.3 1.5 3.9 1.5 3.1 1.6 5.2 9.0 1.9 2.4 23.7 8.8 7.4 1.8 2.3 5.5 2.9 2.9 8.9 21.1 29.0 48.3 34.9 11.0 15.0 11.0 80.4 23.7 63.4 78.3 28.6 12.9 21.1 17.6 22.2 27.6 29.9 36.9 28.8 73.0 31.0 30.0 13.5 66.1 35.0 1.6 46.3 14.4 5.3 6.4 101.5 34.2 9.4 18.8 28.3 44.5 38.2 56.6 21.8 33.3 28.0 30.0 23.9 26.8 32.3 50.7 20.6 14.8 16.6 65.1 40.6 32.1 11.8 34.7 24.3 28.3 20.3 8.8 70.5 41.1 55.2 128.6 30.0 54.1 30.8 32.8 21.2 79.7 0.0 0.0 0.9 0.7 0.2 0.9 1.1 0.4 0.7 0.0 0.3 0.1 0.4 0.9 0.1 0.3 2.8 0.7 0.1 8.3 8.9 8.7 10.3 7.8 8.5 9.4 8.9 9.2 9.0 8.8 8.9 6.0 3.2 3.7 2.3 6.4 5.4 2.7 3.7 0.0 5.9 4.8 5.2 0.9 4.3 2.8 3.7 10.4 15.6 3.7 1.4 0.0 4.5 12.8 11.1 5.8 4.4 0.0 19.8 1.1 3.3 19.1 5.5 1.5 5.0 1.3 7.7 2.9 2.2 7.4 0.0 1.2 1.2 4.1 3.0 2.6 13.1 5.3 2.4 5.4 2.8 5.8 4.6 3.1 1.0 1.5 2.0 0.3 8.6 6.5 2.0 0.2 2.2 14.9 13.9 19.7 8.6 16.0 113.3 44.6 3.2 4.1 5.2 2.7 2.5 2.5 1.7 PSRC1 DDA3 ENSG00000134222 "Proline and serine rich coiled-coil 1" Q6PGN9 1 109279556-109283186 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 101.5;choroid plexus: 47.9;retina: 41.6" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 30.1;Oligodendrocytes: 95.2;Peritubular cells: 44.8;Rod photoreceptor cells: 71.0" "Cancer enriched" "Detected in all" 4 "glioma: 50.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 12.0" "Group enriched" "Detected in many" 11 "dendritic cells: 5.4;granulocytes: 7.1;monocytes: 12.0" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 5 "amygdala: 3.5;cerebral cortex: 7.7;hippocampal formation: 5.7;white matter: 3.4" "Low region specificity" "Detected in all" HPA056561 Supported Nucleoplasm,Cytosol NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol Nucleoplasm "HPA056561: AB_2683175" "unprognostic (1.14e-1)" "unprognostic (1.65e-1)" "unprognostic (1.42e-3)" "unprognostic (6.78e-3)" "unprognostic (2.17e-1)" "unprognostic (4.76e-2)" "prognostic unfavorable (1.36e-9)" "unprognostic (3.51e-2)" "unprognostic (6.21e-2)" "unprognostic (4.88e-3)" "unprognostic (1.76e-2)" "unprognostic (1.92e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (9.43e-2)" "unprognostic (2.08e-1)" "unprognostic (1.90e-1)" "unprognostic (2.12e-1)" 2.0 1.9 64.7 3.8 84.0 7.9 2.4 76.5 84.1 5.1 47.9 3.9 4.3 3.1 2.6 7.6 3.5 3.0 3.0 69.7 71.2 2.7 4.5 5.3 3.6 78.0 79.9 3.3 1.5 3.2 4.2 4.0 83.0 5.5 2.7 41.6 2.4 4.5 0.9 5.2 4.5 3.9 67.9 3.9 3.4 13.3 74.1 14.2 2.3 0.9 4.3 3.2 5.8 101.5 56.0 28.2 112.9 55.1 4.4 8.7 31.0 43.1 34.7 57.6 55.1 43.7 22.7 28.2 15.4 21.4 27.1 38.9 61.4 35.4 48.1 11.0 29.6 17.7 40.5 36.2 5.0 19.0 19.3 10.0 3.3 22.8 16.2 21.5 28.7 32.9 40.9 12.5 46.8 50.5 29.2 12.9 46.9 25.4 31.8 44.4 108.7 9.5 19.6 14.4 47.2 27.3 24.3 36.8 43.6 40.8 22.3 18.0 14.9 35.4 57.9 25.1 72.5 9.7 6.9 9.8 28.6 44.9 100.9 0.0 12.0 1.9 0.6 4.8 0.4 0.0 0.7 0.2 5.4 0.0 0.4 0.3 7.1 0.3 2.7 0.0 0.7 3.4 64.7 84.0 76.5 84.1 69.7 71.2 78.0 79.9 83.0 67.9 74.1 101.5 0.7 0.0 3.9 9.8 0.5 2.0 1.8 2.3 0.6 6.7 2.1 5.6 1.3 1.5 0.5 1.8 25.0 17.6 1.0 2.0 0.0 0.9 1.1 0.5 3.2 2.3 0.0 0.8 19.3 0.9 30.1 4.4 0.5 1.1 1.3 12.9 2.9 1.2 10.9 3.3 3.8 3.9 4.1 4.4 1.8 2.6 5.9 4.9 1.8 2.8 2.2 10.0 0.0 18.1 95.2 0.5 0.6 44.8 0.6 1.0 0.6 2.9 0.9 71.0 0.0 5.5 4.7 5.0 1.5 6.5 1.1 2.9 1.5 1.1 5.4 1.3 PTK2 "FADK, FAK, FAK1, PPP1R71" ENSG00000169398 "Protein tyrosine kinase 2" Q05397 8 140657900-141002216 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Angiogenesis "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 295.2;Excitatory neurons: 584.9;Oligodendrocyte precursor cells: 353.9;Oligodendrocytes: 791.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001842, CAB004036, HPA029671" Approved Supported "Vesicles,Focal adhesion sites,Cytosol" NA Yes 25000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Focal adhesion sites" "Vesicles, Cytosol" "CAB004036: AB_2269034, HPA001842: AB_1855891, HPA029671: AB_10610288" "prognostic unfavorable (3.21e-4)" "unprognostic (3.86e-2)" "unprognostic (1.95e-1)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.93e-1)" "unprognostic (2.28e-1)" "unprognostic (3.02e-2)" "unprognostic (1.27e-1)" "unprognostic (1.97e-1)" "unprognostic (2.96e-2)" "unprognostic (1.06e-2)" "unprognostic (2.38e-1)" "unprognostic (2.80e-2)" "unprognostic (2.94e-2)" "unprognostic (1.11e-1)" "unprognostic (1.53e-1)" "unprognostic (2.90e-2)" 51.0 40.4 83.8 19.5 115.1 6.7 42.1 62.4 99.9 40.3 51.0 37.2 25.8 37.3 49.7 25.6 34.0 32.1 36.9 84.5 77.3 42.6 30.1 39.4 25.3 79.1 87.6 33.7 32.1 53.1 21.3 74.2 81.0 34.0 35.3 35.5 39.9 41.6 38.7 29.6 29.5 37.6 67.6 22.8 32.8 38.9 86.7 11.9 38.7 39.4 25.8 43.9 34.0 154.5 52.6 81.9 111.0 40.3 45.8 48.8 71.6 50.8 70.0 46.3 45.3 35.9 42.1 31.7 111.7 65.3 65.0 60.3 66.1 116.0 69.6 0.3 30.8 70.1 44.3 50.0 62.5 0.1 31.8 33.4 55.8 58.0 81.0 121.5 139.0 44.0 72.0 0.8 62.9 91.0 0.9 0.7 43.2 113.2 90.3 46.8 60.9 1.5 97.7 117.3 43.9 54.8 79.0 25.0 52.0 97.2 59.2 1.2 84.9 45.2 85.5 54.0 58.1 0.0 0.6 3.4 58.7 0.6 62.9 1.6 3.3 0.0 0.2 1.4 0.0 5.3 0.6 0.0 4.5 6.3 4.4 1.6 1.3 4.7 0.8 6.1 0.2 3.9 83.8 115.1 62.4 99.9 84.5 77.3 79.1 87.6 81.0 67.6 86.7 154.5 71.3 32.1 33.1 295.2 20.6 33.3 70.1 36.3 64.9 55.2 29.3 23.5 29.6 32.9 32.1 55.2 60.5 37.0 8.0 23.1 23.5 27.2 68.4 29.3 43.3 54.3 25.8 8.4 584.9 23.3 53.7 37.2 37.8 46.5 9.5 84.7 37.5 15.7 8.1 67.3 263.6 23.0 30.5 15.2 15.9 38.8 23.9 19.4 24.9 159.3 3.9 40.9 0.0 353.9 791.4 43.1 23.5 21.8 1.7 82.4 29.3 25.6 33.7 55.0 98.6 32.7 128.4 88.9 65.5 42.8 25.9 33.2 3.4 67.0 24.1 87.3 PTMS ParaT ENSG00000159335 Parathymosin P20962 12 6765516-6770952 "Predicted intracellular proteins" Immunity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 565.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 25.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 25.6" "Cell line enhanced" "Detected in all" "HDLM-2: 672.8" HPA038186 Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim" No Yes 300000 "Cluster 41: Basophils - Cellular respiration" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA038186: AB_10673042" "unprognostic (3.11e-2)" "unprognostic (1.31e-3)" "unprognostic (1.76e-1)" "unprognostic (3.57e-2)" "unprognostic (1.09e-1)" "unprognostic (2.83e-1)" "unprognostic (1.13e-1)" "unprognostic (2.47e-1)" "unprognostic (4.16e-1)" "unprognostic (1.01e-1)" "unprognostic (8.69e-3)" "unprognostic (2.52e-1)" "prognostic unfavorable (6.18e-5)" "unprognostic (1.02e-1)" "unprognostic (3.21e-1)" "unprognostic (2.35e-3)" "unprognostic (1.55e-2)" 138.4 78.4 115.9 37.0 105.9 14.3 121.4 103.2 122.3 188.2 48.6 293.9 33.0 243.9 29.0 128.0 145.3 28.9 98.7 117.0 74.3 186.6 565.2 173.5 22.7 45.9 43.5 239.9 50.3 82.4 96.3 49.4 48.0 194.3 28.9 64.6 94.4 86.8 56.3 116.8 101.1 98.8 31.6 61.4 109.5 32.6 86.0 16.3 109.5 16.2 20.1 176.6 137.5 72.5 49.2 250.8 324.8 320.3 149.8 126.2 127.5 210.9 189.2 157.6 130.1 153.8 190.2 19.5 151.8 321.7 143.2 104.6 178.7 159.3 61.9 672.8 219.1 27.5 160.6 58.1 174.1 7.7 56.6 123.7 68.8 121.4 245.6 237.7 175.3 8.6 175.5 50.6 139.8 144.1 9.2 40.7 347.6 92.2 180.8 4.2 99.8 39.6 124.7 12.5 107.4 363.6 254.7 86.9 186.1 230.0 75.9 23.4 296.7 239.6 344.2 36.6 195.2 42.4 19.3 25.4 196.5 18.1 183.6 25.6 0.4 3.6 1.3 0.1 0.6 0.1 0.1 1.1 0.3 0.0 0.0 0.1 1.3 0.1 0.0 4.4 0.5 0.4 115.9 105.9 103.2 122.3 117.0 74.3 45.9 43.5 48.0 31.6 86.0 72.5 370.5 0.0 14.1 9.4 22.8 289.5 328.0 44.6 257.8 325.5 239.2 275.5 10.4 88.6 16.7 154.5 200.1 153.6 88.4 99.8 234.8 61.9 6.6 73.1 494.8 342.7 513.3 248.6 28.7 34.0 404.0 292.4 66.3 117.5 52.8 216.3 325.2 710.0 491.3 116.1 15.2 229.4 22.4 100.4 309.4 23.1 489.6 136.8 227.7 12.2 76.7 512.6 4.1 13.0 3.1 38.3 141.3 692.1 38.8 399.9 244.2 547.6 11.4 357.7 598.2 232.0 411.7 7.4 32.8 259.4 249.2 163.2 81.3 122.5 198.9 206.7 PTPRM "hR-PTPu, PTPRL1, RPTPU" ENSG00000173482 "Protein tyrosine phosphatase receptor type M" P28827 18 7566782-8406861 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 142.0;Astrocytes: 188.1;Inhibitory neurons: 751.6;Microglial cells: 263.3;Oligodendrocyte precursor cells: 224.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory CD8 T-cell: 4.7" "Group enriched" "Detected in many" 33 "dendritic cells: 1.8;T-cells: 4.7" "Cell line enhanced" "Detected in many" "ASC diff: 98.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003891, CAB022442, CAB022443" Supported Approved "Plasma membrane" NA Yes 130000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "CAB022442: , CAB022443: , HPA003891: AB_2667073" "unprognostic (2.59e-1)" "prognostic unfavorable (8.65e-5)" "unprognostic (4.89e-2)" "unprognostic (1.00e-1)" "unprognostic (1.13e-1)" "unprognostic (1.46e-1)" "unprognostic (1.80e-1)" "unprognostic (3.41e-2)" "unprognostic (7.62e-2)" "unprognostic (2.74e-2)" "unprognostic (1.56e-2)" "unprognostic (9.64e-2)" "unprognostic (5.63e-2)" "unprognostic (3.11e-3)" "unprognostic (9.41e-2)" "unprognostic (2.63e-2)" "prognostic favorable (1.07e-4)" 53.1 24.1 18.9 11.9 37.6 1.2 41.8 13.0 27.7 18.4 44.2 25.3 8.7 24.2 11.9 14.2 23.3 32.4 61.2 12.7 38.7 29.5 11.8 38.9 15.5 21.7 53.0 26.4 13.2 23.4 16.1 33.2 34.3 16.7 11.5 19.3 10.9 36.0 52.5 12.3 15.1 24.8 5.8 23.1 18.4 22.8 47.6 16.7 54.8 63.4 11.9 23.9 12.2 14.4 4.6 33.4 15.7 0.2 98.0 67.4 38.7 41.1 35.6 26.9 39.5 30.9 7.1 0.0 39.0 49.1 0.5 0.3 0.2 14.3 36.9 0.5 7.2 0.0 22.2 15.2 27.9 0.0 0.4 77.1 29.3 14.9 42.1 51.1 27.2 0.0 0.0 13.8 21.8 0.7 13.7 0.3 2.6 9.9 7.3 0.5 13.5 63.9 64.9 57.6 1.4 8.6 1.1 0.2 34.6 24.9 0.2 0.0 28.2 54.9 34.6 26.4 7.2 1.1 0.4 0.3 46.8 0.2 10.4 0.0 0.0 0.0 2.8 0.0 1.1 0.0 3.8 4.7 0.0 0.0 1.0 2.0 0.0 0.0 0.0 1.8 0.7 1.1 18.9 37.6 13.0 27.7 12.7 38.7 21.7 53.0 34.3 5.8 47.6 14.4 142.0 44.8 36.0 188.1 1.1 6.0 7.3 3.0 2.8 28.3 2.5 3.2 26.7 14.3 7.1 5.5 2.1 11.4 5.4 0.9 1.9 17.6 25.9 28.9 15.6 68.9 1.8 0.4 70.1 8.3 3.4 14.0 8.2 59.6 2.5 13.0 47.2 25.3 9.9 0.0 751.6 1.4 0.0 8.0 5.7 42.0 2.8 5.1 30.2 263.3 0.6 2.9 3.1 224.7 50.3 14.3 1.2 5.3 2.3 8.3 3.0 13.3 15.6 2.2 6.6 7.4 9.9 8.6 9.9 0.9 2.8 12.6 5.7 3.7 0.8 8.6 PTTG1 "EAP1, HPTTG, PTTG, securin, TUTR1" ENSG00000164611 "PTTG1 regulator of sister chromatid separation, securin" O95997 5 160421855-160428739 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, DNA damage, DNA repair, Mitosis" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 160.1;lymphoid tissue: 144.9;testis: 175.6" "Cell type enhanced" "Detected in many" "Early spermatids: 770.5;Erythroid cells: 415.9;Langerhans cells: 412.3;Spermatocytes: 708.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 218.0" "Lineage enriched" "Detected in all" 7 "T-cells: 218.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008373, HPA008890, HPA045034" Enhanced Supported Nucleoli,Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol Nucleoli "CAB008373: AB_592493, HPA008890: AB_1079717, HPA045034: AB_2679192" "unprognostic (6.48e-2)" "unprognostic (1.03e-2)" "unprognostic (1.40e-3)" "unprognostic (4.46e-3)" "unprognostic (5.81e-2)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.62e-6)" "unprognostic (7.50e-3)" "unprognostic (5.24e-2)" "unprognostic (3.47e-2)" "unprognostic (2.13e-3)" "unprognostic (6.70e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.17e-2)" "unprognostic (1.72e-1)" "unprognostic (4.23e-2)" "unprognostic (3.35e-2)" 3.7 3.5 4.2 25.2 5.3 160.1 10.9 4.1 11.5 9.6 4.0 33.9 24.6 4.8 9.6 59.7 5.0 6.1 3.5 8.1 6.6 3.0 5.3 8.7 81.5 3.9 4.8 1.8 1.5 2.3 4.3 21.2 4.2 3.1 44.1 2.4 10.3 2.7 2.5 36.0 24.1 19.2 4.0 18.6 11.8 175.6 5.3 127.0 79.3 1.3 144.9 12.5 19.9 4.7 345.4 178.2 385.8 279.5 64.4 63.3 120.8 177.5 406.1 463.4 503.5 341.1 294.9 373.3 154.7 204.2 527.5 176.1 243.5 496.1 661.2 428.3 220.3 196.7 241.8 208.6 13.0 181.5 165.6 29.6 81.5 315.4 189.5 139.9 333.4 243.3 160.7 282.3 485.4 162.3 220.7 446.1 197.5 279.3 251.4 199.4 452.4 320.7 239.6 82.6 241.0 151.3 258.6 156.3 535.6 309.3 319.9 195.7 144.8 208.3 275.9 164.9 531.3 239.2 235.6 432.3 225.9 310.4 379.6 9.7 3.2 10.3 25.5 8.7 9.6 30.9 52.3 60.6 23.9 23.5 12.7 31.4 3.0 14.6 5.8 22.6 218.0 19.8 4.2 5.3 4.1 11.5 8.1 6.6 3.9 4.8 4.2 4.0 5.3 4.7 11.8 6.4 21.5 0.0 40.0 247.9 64.5 163.6 142.3 3.4 15.8 40.5 4.0 4.3 31.1 5.5 0.0 125.4 38.3 17.7 3.9 5.8 770.5 22.7 9.3 20.6 6.0 415.9 1.3 5.3 196.2 35.6 28.1 16.7 37.5 66.2 18.5 7.1 87.5 0.0 1.6 39.2 126.1 36.3 412.3 105.1 11.1 39.1 87.2 0.0 24.7 3.5 6.2 0.0 0.6 3.0 10.7 7.9 91.4 54.1 9.0 2.0 17.1 1.0 6.6 18.6 43.2 708.0 57.3 232.0 156.1 31.9 73.7 16.8 70.3 50.3 PTTG1IP "C21orf1, C21orf3, PBF" ENSG00000183255 "PTTG1 interacting protein" P53801 21 44849585-44873903 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034146, HPA061827" Uncertain Supported Nucleoplasm NA Yes 26000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB034146: AB_1568894, HPA061827: AB_2684620" "unprognostic (1.78e-2)" "prognostic unfavorable (8.61e-4)" "unprognostic (5.24e-3)" "unprognostic (3.18e-2)" "unprognostic (1.68e-2)" "unprognostic (2.03e-2)" "unprognostic (3.59e-2)" "unprognostic (1.22e-2)" "unprognostic (1.98e-2)" "unprognostic (3.77e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (9.30e-2)" "unprognostic (3.17e-2)" "prognostic unfavorable (5.40e-4)" "unprognostic (1.38e-2)" "unprognostic (8.88e-2)" "unprognostic (1.90e-1)" 127.8 131.8 147.6 98.4 158.9 92.0 114.0 150.8 146.8 131.1 131.1 132.7 123.2 132.4 118.5 89.1 109.4 141.8 164.3 138.1 168.7 157.6 130.5 160.5 75.3 178.8 152.9 110.7 85.6 84.1 68.8 180.1 169.9 108.5 111.5 29.7 118.3 151.4 70.7 88.9 127.3 145.0 152.0 97.7 169.9 66.9 175.3 57.9 127.4 63.2 62.0 139.6 93.3 157.5 245.3 134.6 155.3 148.2 300.6 174.8 127.0 212.9 309.8 174.1 166.6 290.0 323.9 32.9 789.8 344.4 417.0 109.8 73.0 140.2 161.1 56.3 81.0 254.3 80.0 260.1 293.8 97.6 83.5 269.9 225.1 189.1 130.8 346.3 376.6 88.6 131.7 83.1 539.5 106.0 71.0 99.5 166.8 352.9 169.8 70.4 158.4 162.0 735.6 82.7 117.2 182.0 240.0 262.5 482.0 188.7 203.7 163.7 511.8 216.9 126.5 170.6 340.0 78.5 79.4 42.2 146.7 220.6 199.8 336.2 181.2 109.1 48.4 146.7 79.5 25.5 62.7 51.3 203.3 23.6 59.7 41.0 248.8 67.3 167.0 92.5 87.3 223.7 147.6 158.9 150.8 146.8 138.1 168.7 178.8 152.9 169.9 152.0 175.3 157.5 140.9 394.2 169.6 39.8 28.0 50.7 84.1 181.3 61.5 14.6 102.0 96.8 173.0 75.8 248.9 145.3 6.2 218.6 56.8 321.4 49.0 323.0 51.5 115.0 115.0 191.6 79.3 37.8 8.5 120.6 72.7 117.1 140.6 187.7 81.5 181.3 124.2 102.2 109.3 11.8 10.7 89.1 130.2 88.0 69.6 98.7 72.1 136.3 87.2 22.5 91.1 78.8 51.5 20.1 31.9 294.3 255.2 98.9 36.4 112.8 268.1 71.2 192.3 15.2 65.7 61.1 127.9 73.7 43.4 92.4 42.9 366.7 45.6 54.6 100.3 169.9 PYURF PreY ENSG00000145337 "PIGY upstream reading frame" Q96I23 4 88520998-88523776 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA036455 Uncertain Approved Nucleoplasm NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 32: Non-specific - Translation" Nucleoplasm "HPA036455: AB_10673388" "unprognostic (8.25e-2)" "unprognostic (9.14e-2)" "unprognostic (6.61e-2)" "unprognostic (2.03e-1)" "unprognostic (5.03e-2)" "unprognostic (7.23e-2)" "unprognostic (1.10e-2)" "unprognostic (8.84e-3)" "unprognostic (3.64e-1)" "unprognostic (1.48e-2)" "unprognostic (1.20e-2)" "unprognostic (2.35e-2)" "unprognostic (9.04e-3)" "unprognostic (1.59e-1)" "unprognostic (1.16e-1)" "unprognostic (1.01e-1)" "unprognostic (4.78e-3)" 71.2 72.2 35.1 23.1 37.0 44.5 70.4 38.7 43.4 69.0 33.8 72.0 30.7 74.8 45.6 64.1 65.5 22.5 58.6 34.0 37.3 84.9 81.7 56.4 27.8 36.7 35.6 65.2 59.0 41.9 66.2 28.5 36.5 61.9 31.2 22.9 55.4 33.9 66.9 67.0 53.9 36.2 39.2 54.4 56.8 42.3 36.2 27.3 54.5 42.3 29.4 61.7 62.5 39.3 60.1 19.8 39.1 46.4 76.7 78.3 26.2 43.2 60.6 53.1 44.6 15.5 46.3 0.2 47.3 61.7 36.4 25.2 35.6 54.4 66.6 73.4 61.8 66.2 24.8 59.9 58.0 110.7 40.9 54.4 80.8 34.5 69.5 50.4 88.5 20.4 75.9 64.9 77.8 45.5 68.5 67.6 32.7 70.5 37.5 68.0 36.3 69.8 44.4 33.4 46.7 45.7 54.9 49.4 119.9 38.4 23.0 54.8 60.6 56.1 51.9 55.3 40.6 45.6 40.1 7.5 49.3 55.7 63.1 82.4 92.1 79.0 90.4 94.9 102.2 98.9 103.2 98.3 111.0 80.5 105.4 101.6 18.1 108.9 95.3 68.3 116.8 186.1 35.1 37.0 38.7 43.4 34.0 37.3 36.7 35.6 36.5 39.2 36.2 39.3 136.2 51.3 71.3 0.0 92.0 230.4 176.0 167.2 158.8 28.7 207.2 205.2 5.8 84.4 98.8 86.5 10.4 232.3 106.8 65.5 287.6 118.0 44.0 69.7 103.9 127.0 114.6 98.2 0.0 129.5 120.6 119.6 53.5 51.2 105.8 97.7 114.2 147.3 139.4 26.9 0.0 99.4 101.7 115.9 124.7 98.3 125.9 100.0 348.6 0.0 129.2 113.3 176.1 0.0 0.0 103.4 102.7 120.0 84.6 208.7 128.0 236.9 79.1 33.0 59.2 107.3 109.2 108.1 62.3 189.9 289.0 163.9 119.6 136.5 132.8 142.3 RAB10 ENSG00000084733 "RAB10, member RAS oncogene family" P61026 2 26034084-26137454 "Enzymes, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 488.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045611 Approved NA Yes 4300000 "Cluster 51: Monocytes - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 10: Non-specific - Unknown function" "HPA045611: AB_10961124" "unprognostic (7.73e-3)" "unprognostic (2.45e-2)" "unprognostic (8.21e-3)" "prognostic unfavorable (7.40e-4)" "unprognostic (8.22e-3)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.99e-5)" "unprognostic (9.22e-3)" "unprognostic (6.14e-2)" "unprognostic (2.96e-2)" "prognostic unfavorable (7.37e-5)" "unprognostic (1.06e-2)" "unprognostic (8.69e-3)" "unprognostic (1.05e-1)" "unprognostic (2.39e-1)" "unprognostic (1.31e-1)" "unprognostic (2.99e-2)" 47.4 51.5 42.8 44.2 49.0 17.7 45.1 48.7 56.7 55.6 29.7 58.8 41.3 38.9 40.3 172.9 39.6 41.9 49.8 41.2 47.3 56.8 48.5 39.9 42.8 52.9 46.9 37.1 37.7 66.3 21.5 40.9 54.4 42.6 57.9 29.0 51.7 41.6 213.9 71.0 46.3 48.1 51.5 44.4 58.8 24.0 46.4 43.8 54.2 114.0 64.5 78.5 78.1 62.8 117.1 139.7 63.8 53.1 131.2 108.2 61.9 90.3 76.8 69.7 61.6 83.2 83.8 77.9 83.4 96.7 79.5 62.0 77.3 84.4 73.9 82.3 56.0 135.1 54.4 134.8 122.6 112.2 73.5 89.0 135.9 85.9 100.3 109.6 89.0 48.9 114.1 76.7 95.1 52.0 69.1 87.1 65.2 139.5 81.7 65.2 133.4 132.8 141.6 111.8 90.1 83.7 75.2 135.1 94.9 70.5 59.5 80.1 110.2 107.1 56.2 75.7 97.2 50.5 84.2 124.4 107.9 132.6 83.5 58.0 75.5 35.5 31.5 135.2 38.6 33.4 36.9 34.1 69.9 32.0 31.1 35.2 54.6 50.6 152.6 24.3 44.6 81.0 42.8 49.0 48.7 56.7 41.2 47.3 52.9 46.9 54.4 51.5 46.4 62.8 70.8 80.1 49.7 37.9 56.2 341.8 195.5 156.4 122.3 23.8 85.2 64.6 76.4 85.8 134.7 92.0 8.4 121.0 48.7 168.8 115.4 188.3 35.5 67.8 76.7 78.4 65.2 101.0 43.6 96.0 204.4 80.7 97.3 98.3 50.7 44.0 53.2 66.8 159.7 26.9 36.0 94.1 107.8 157.2 285.1 29.6 62.7 151.6 88.9 36.5 246.8 104.9 38.1 47.7 78.1 136.8 123.8 70.0 63.6 199.7 85.9 135.2 107.4 32.7 85.5 94.1 159.5 85.3 73.4 255.9 488.0 128.3 59.3 65.6 117.7 334.3 RAC2 EN-7 ENSG00000128340 "Rac family small GTPase 2" P15153 22 37225270-37244448 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 411.9;lymphoid tissue: 387.9" "Cell type enhanced" "Detected in many" "B-cells: 329.0;dendritic cells: 381.4;granulocytes: 520.5;NK-cells: 717.9;Plasma cells: 287.8;T-cells: 419.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 522.5;HL-60: 734.5;HMC-1: 1427.9;Karpas-707: 684.5;U-87 MG: 618.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022946, HPA047820" Enhanced NA Yes 3300000 "Cluster 5: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB022946: , HPA047820: AB_2680167" "prognostic favorable (1.03e-5)" "unprognostic (2.91e-1)" "unprognostic (3.21e-2)" "unprognostic (1.82e-3)" "unprognostic (6.74e-2)" "unprognostic (7.78e-2)" "unprognostic (3.47e-1)" "unprognostic (5.00e-2)" "unprognostic (8.52e-3)" "unprognostic (2.65e-1)" "unprognostic (7.65e-2)" "unprognostic (3.81e-1)" "prognostic unfavorable (1.06e-6)" "unprognostic (1.45e-1)" "unprognostic (1.75e-1)" "unprognostic (6.21e-2)" "unprognostic (1.50e-2)" 24.7 8.4 3.6 207.2 3.8 411.9 11.4 3.9 8.0 12.2 4.4 34.8 35.3 10.1 4.7 15.9 11.7 37.1 6.5 3.8 4.7 10.9 19.3 63.4 387.9 6.5 5.3 5.5 5.3 2.1 3.4 12.4 7.1 10.9 33.9 0.4 21.5 8.3 4.9 7.6 96.9 19.6 5.2 299.9 42.7 3.5 6.1 323.9 9.5 7.2 309.1 54.0 9.9 7.2 136.6 0.2 0.0 0.0 14.3 130.5 0.6 17.9 41.1 14.2 28.8 0.3 44.8 167.4 19.8 52.9 0.8 33.3 1.0 231.6 15.6 522.5 0.6 209.6 3.6 0.6 35.8 734.5 1427.9 96.4 32.3 25.1 84.3 0.9 239.7 159.1 50.5 684.5 1.9 0.2 218.9 291.2 2.8 13.1 87.2 72.3 0.7 193.8 22.6 0.1 2.0 0.6 0.9 23.0 2.7 0.8 9.7 391.8 258.7 0.6 23.5 1.0 2.0 307.0 171.4 176.6 618.6 316.5 35.1 1319.9 519.8 1602.2 972.1 695.5 731.5 761.7 768.6 858.9 494.0 672.8 584.3 759.8 1336.4 972.2 879.5 728.7 1163.4 1566.2 3.6 3.8 3.9 8.0 3.8 4.7 6.5 5.3 7.1 5.2 6.1 7.2 4.4 16.0 47.7 0.0 329.0 5.4 2.2 26.0 16.5 0.0 8.6 9.5 1.1 2.8 12.6 1.8 0.0 0.8 381.4 3.4 0.0 13.6 0.2 1.1 0.8 5.6 4.2 109.7 0.4 2.2 1.5 9.2 33.6 1.0 520.5 0.3 13.6 3.4 150.8 0.0 0.1 6.3 0.0 129.9 63.9 0.9 0.3 147.9 30.2 3.7 125.9 0.0 717.9 0.5 0.0 18.2 18.1 0.0 287.8 0.5 0.6 1.5 4.4 0.0 13.1 2.4 4.5 0.0 1.0 5.1 4.0 2.9 419.6 3.7 11.2 3.6 RACGAP1 MgcRacGAP ENSG00000161800 "Rac GTPase activating protein 1" Q9H0H5 12 49976923-50033136 "Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Ion transport, Spermatogenesis, Transport" "Developmental protein, GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 38.9;lymphoid tissue: 43.0;testis: 45.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 55.7;Extravillous trophoblasts: 49.4;Spermatocytes: 79.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025859, HPA039427, HPA043912" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB025859: , HPA039427: AB_2676503, HPA043912: AB_2678728" "prognostic unfavorable (1.51e-4)" "unprognostic (1.91e-1)" "unprognostic (3.74e-3)" "unprognostic (1.53e-2)" "unprognostic (1.58e-1)" "unprognostic (4.82e-2)" "prognostic unfavorable (1.86e-6)" "unprognostic (1.15e-3)" "unprognostic (3.07e-3)" "unprognostic (5.31e-2)" "prognostic unfavorable (4.12e-6)" "unprognostic (5.56e-2)" "prognostic unfavorable (3.98e-8)" "unprognostic (3.13e-2)" "unprognostic (4.94e-1)" "unprognostic (6.16e-2)" "unprognostic (2.15e-1)" 5.0 2.5 5.5 13.7 8.2 38.9 7.1 6.9 6.3 5.2 3.2 16.7 10.5 5.3 1.5 21.3 4.4 6.4 2.8 5.0 6.0 9.2 4.7 6.2 23.9 6.7 7.1 2.4 2.7 5.8 1.4 14.0 6.5 3.3 18.7 5.3 4.8 3.4 4.9 14.4 11.6 12.5 5.5 6.5 9.8 45.5 7.6 43.0 3.3 4.8 30.2 7.7 8.0 7.0 193.0 174.5 135.8 86.8 24.8 29.7 113.0 195.0 97.0 207.3 140.3 174.6 144.7 107.5 86.0 108.3 99.9 127.1 137.7 93.6 219.9 203.0 85.4 137.9 165.8 58.1 8.4 146.1 109.0 16.2 17.2 140.7 111.4 60.3 71.7 96.4 101.6 159.6 197.0 136.8 122.5 72.6 96.2 108.9 112.9 113.9 163.5 78.3 54.9 95.7 113.9 97.5 161.7 102.7 53.0 68.8 199.7 64.8 64.9 136.2 119.1 86.8 144.7 83.3 225.2 126.6 67.7 97.0 81.1 24.1 3.2 4.7 6.5 4.1 5.7 8.2 7.9 9.2 2.8 4.3 4.6 6.1 0.7 11.0 2.6 1.8 19.1 5.8 5.5 8.2 6.9 6.3 5.0 6.0 6.7 7.1 6.5 5.5 7.6 7.0 2.0 6.4 6.4 2.9 4.2 12.9 2.5 4.9 6.2 1.5 4.8 5.1 1.5 2.8 3.3 5.5 4.2 21.8 4.4 3.1 19.6 1.9 15.2 2.2 3.1 2.7 0.0 55.7 7.5 2.2 49.4 5.9 7.7 4.0 2.5 14.2 5.3 2.7 13.1 1.7 8.0 5.7 20.3 11.3 8.0 17.7 1.5 7.1 1.8 1.0 4.5 2.7 6.2 6.0 12.3 2.0 1.0 3.8 10.9 2.8 1.1 2.1 2.3 0.8 13.1 3.1 5.5 79.6 32.2 19.5 12.9 8.6 6.9 2.2 11.6 2.9 RAD1 "HRAD1, REC1" ENSG00000113456 "RAD1 checkpoint DNA exonuclease" O60671 5 34905260-34918989 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006692 Approved Approved Nucleoplasm,Vesicles NA Yes "Cluster 6: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 20: HeLa - Mitochondria" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Vesicles" "HPA006692: AB_2667645" "prognostic unfavorable (6.30e-4)" "unprognostic (1.85e-2)" "unprognostic (9.40e-2)" "unprognostic (1.98e-3)" "unprognostic (2.00e-1)" "unprognostic (2.38e-2)" "prognostic unfavorable (1.06e-5)" "unprognostic (1.22e-2)" "unprognostic (2.25e-3)" "unprognostic (1.61e-3)" "unprognostic (2.57e-1)" "unprognostic (2.57e-1)" "unprognostic (2.22e-2)" "unprognostic (1.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.11e-1)" "unprognostic (3.12e-3)" 3.5 8.1 3.2 4.8 3.5 8.4 5.8 3.9 4.6 6.8 5.3 4.1 4.9 5.6 5.4 4.9 3.9 4.6 8.9 3.8 4.6 5.1 4.3 7.5 8.9 3.5 2.7 5.7 4.4 5.1 3.5 8.1 3.2 6.8 4.3 8.7 4.9 4.8 10.9 6.7 4.8 4.6 1.9 4.9 4.8 7.9 3.4 6.3 6.3 8.6 6.2 5.2 4.7 3.8 8.5 10.2 12.3 20.5 7.9 9.4 17.2 15.1 12.0 13.0 10.6 12.2 12.3 25.0 5.2 11.2 15.7 8.4 12.6 7.6 14.4 10.1 12.7 12.9 34.0 8.0 11.9 16.5 11.9 7.8 7.3 13.9 9.3 6.1 6.2 11.0 22.7 13.2 11.2 10.2 19.6 13.9 15.4 6.0 15.7 17.1 24.0 8.6 6.7 9.0 12.4 13.3 30.0 19.9 13.3 7.6 12.5 14.8 6.2 17.9 13.3 9.7 14.4 7.9 13.8 20.3 11.1 28.6 12.5 7.4 2.9 6.5 5.3 2.8 6.9 8.6 5.8 7.6 3.1 9.1 8.2 6.8 1.6 4.5 2.8 6.9 4.9 2.6 3.2 3.5 3.9 4.6 3.8 4.6 3.5 2.7 3.2 1.9 3.4 3.8 11.5 22.4 43.2 5.9 18.3 29.2 20.2 29.3 13.1 25.3 23.9 18.4 25.7 14.3 21.3 20.2 27.1 82.3 20.4 11.9 19.6 18.1 22.0 13.1 16.6 14.1 13.1 28.2 6.6 22.5 54.4 18.7 6.1 12.0 21.5 39.1 10.0 14.8 23.4 23.5 9.0 12.7 30.5 12.0 19.3 16.8 25.1 13.1 17.8 6.5 12.7 23.9 9.2 7.5 9.1 17.8 13.8 21.8 18.0 21.9 13.4 16.4 14.6 35.6 13.1 19.6 19.4 72.5 58.6 15.6 28.6 80.6 22.3 27.4 13.0 25.8 RAD18 RNF73 ENSG00000070950 "RAD18 E3 ubiquitin protein ligase" Q9NS91 3 8775402-8963773 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006716, HPA006724, HPA008752" Supported Approved Enhanced "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nuclear bodies" "HPA006716: AB_2667650, HPA006724: AB_2667655, HPA008752: AB_2668129" "unprognostic (1.26e-1)" "unprognostic (1.07e-1)" "unprognostic (4.45e-2)" "unprognostic (1.25e-3)" "unprognostic (2.73e-2)" "unprognostic (6.15e-2)" "prognostic unfavorable (1.12e-4)" "unprognostic (2.01e-1)" "unprognostic (9.76e-2)" "unprognostic (1.17e-1)" "unprognostic (2.02e-2)" "prognostic unfavorable (3.73e-4)" "prognostic unfavorable (3.65e-5)" "unprognostic (1.97e-2)" "unprognostic (1.51e-1)" "unprognostic (7.92e-2)" "unprognostic (1.89e-2)" 2.7 2.3 1.2 3.3 1.5 5.2 5.3 1.3 1.7 3.2 0.5 3.8 10.1 2.8 1.9 3.4 2.3 3.1 1.8 1.5 0.9 1.6 2.7 2.7 4.6 1.6 1.0 2.8 1.7 2.0 1.3 3.0 1.5 3.2 4.9 2.6 3.2 1.6 1.3 4.5 6.5 2.8 1.2 3.5 2.2 2.9 1.1 5.8 3.7 1.0 4.4 2.5 2.9 2.3 16.2 15.2 12.3 7.4 3.0 6.4 14.9 25.0 8.5 23.5 16.1 13.7 10.1 19.8 4.7 14.2 13.8 5.6 13.1 13.0 23.8 12.2 17.2 16.9 16.1 8.2 1.9 22.7 13.9 2.4 4.6 23.3 15.7 6.3 7.7 17.1 18.2 19.0 20.9 18.6 22.9 15.9 17.2 12.7 28.5 18.0 13.6 15.6 6.9 12.2 5.1 11.5 11.2 10.5 8.2 9.7 11.0 9.8 6.4 19.4 10.5 16.8 21.7 9.6 16.1 43.7 14.3 24.5 14.6 6.4 1.6 5.1 1.5 1.7 2.8 1.9 2.1 2.7 2.0 1.9 2.2 1.6 0.7 2.8 1.1 3.6 3.0 0.8 1.2 1.5 1.3 1.7 1.5 0.9 1.6 1.0 1.5 1.2 1.1 2.3 5.7 16.0 9.8 6.2 7.7 11.1 7.5 6.4 5.7 4.6 7.3 11.7 2.2 4.3 7.5 3.7 2.1 9.0 8.6 5.2 1.9 9.6 4.2 4.0 5.8 4.6 1.8 7.2 20.9 8.2 12.4 6.8 3.6 4.9 13.9 14.8 6.1 3.1 7.1 3.3 15.7 6.5 2.0 5.2 5.6 3.0 4.1 4.6 3.6 14.0 7.1 3.2 8.2 16.1 14.3 10.2 4.3 2.6 8.7 6.4 4.0 3.1 4.1 2.3 6.6 4.3 6.9 26.2 14.0 6.0 11.8 6.7 7.5 9.3 6.3 3.6 RAD21 "hHR21, KIAA0078, SCC1" ENSG00000164754 "RAD21 cohesin complex component" O60216 8 116845934-116874776 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Activator, Developmental protein, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 424.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020044, CAB022065, HPA073277" Supported Enhanced Nucleoplasm NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "CAB022065: , HPA020044: AB_1856035, HPA073277: " "unprognostic (7.85e-2)" "unprognostic (4.92e-1)" "unprognostic (3.05e-1)" "unprognostic (5.43e-3)" "unprognostic (9.56e-2)" "unprognostic (3.50e-1)" "prognostic unfavorable (1.71e-4)" "unprognostic (1.86e-3)" "unprognostic (8.99e-2)" "unprognostic (8.80e-2)" "unprognostic (5.58e-3)" "unprognostic (3.56e-2)" "unprognostic (4.40e-2)" "unprognostic (2.00e-1)" "unprognostic (1.82e-1)" "unprognostic (1.39e-1)" "unprognostic (1.95e-1)" 75.4 80.5 62.9 74.0 74.5 206.0 71.9 74.7 75.7 50.5 56.7 73.1 57.3 67.6 54.6 71.2 50.6 49.4 89.8 58.1 74.3 68.2 64.7 67.9 122.8 70.0 69.3 67.8 41.9 82.3 33.8 90.1 75.2 57.5 82.5 114.2 56.9 65.0 76.6 54.0 60.4 60.2 71.9 75.5 56.4 88.7 67.2 177.2 80.9 95.5 119.5 59.7 44.5 97.1 301.6 143.9 277.3 156.7 136.5 117.0 124.2 202.1 191.4 220.8 202.4 119.8 275.2 438.6 109.4 146.0 117.4 162.4 238.5 132.1 257.6 589.1 153.1 447.6 167.2 153.7 85.5 145.7 253.1 100.2 106.0 129.4 156.0 146.1 176.4 625.8 183.6 595.6 193.1 181.1 665.4 86.2 163.6 385.4 179.2 241.8 201.5 223.4 133.5 173.3 348.2 179.1 212.2 569.4 140.6 144.5 238.3 178.5 128.5 154.6 223.5 164.4 217.1 313.3 383.9 391.9 132.8 206.7 189.7 35.3 7.9 28.0 17.4 8.7 17.5 14.4 20.3 20.6 9.0 12.8 20.8 20.6 29.7 14.3 12.7 7.6 43.7 11.4 62.9 74.5 74.7 75.7 58.1 74.3 70.0 69.3 75.2 71.9 67.2 97.1 115.7 256.4 157.1 24.5 111.2 95.6 77.5 62.5 78.0 75.4 65.8 53.0 155.2 51.5 101.0 55.2 31.3 142.4 118.1 90.4 43.0 54.0 258.0 67.0 86.7 97.0 84.4 249.8 39.3 44.9 157.0 89.4 57.1 88.2 153.5 112.9 75.0 72.1 67.9 67.3 48.1 72.7 69.2 93.1 100.0 424.9 116.5 93.4 69.4 45.9 110.8 112.5 77.2 41.2 58.3 63.5 66.3 106.5 124.0 100.0 35.7 59.4 70.5 67.9 72.3 88.6 85.3 33.2 88.6 103.7 100.4 113.7 134.1 85.5 94.1 95.5 RAD51 "BRCC5, FANCR, HsRad51, HsT16930, RAD51A, RECA" ENSG00000051180 "RAD51 recombinase" Q06609 15 40694774-40732340 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.7;testis: 24.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 35.3;Extravillous trophoblasts: 67.2;Spermatocytes: 53.6;Spermatogonia: 24.8;Syncytiotrophoblasts: 25.3" "Cancer enhanced" "Detected in all" "testis cancer: 19.9" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB010381, HPA039310" Enhanced Supported "Nucleoli rim,Cytosol" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoli rim" Cytosol "CAB010381: AB_2253533, HPA039310: AB_2676434" "prognostic unfavorable (7.94e-4)" "unprognostic (7.20e-3)" "unprognostic (1.22e-1)" "unprognostic (2.72e-2)" "unprognostic (8.23e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (9.33e-4)" "unprognostic (3.40e-3)" "unprognostic (2.53e-2)" "unprognostic (1.76e-1)" "unprognostic (1.41e-3)" "unprognostic (2.53e-3)" "unprognostic (0.00e+0)" "unprognostic (2.26e-2)" "unprognostic (2.34e-1)" "unprognostic (9.59e-2)" "unprognostic (1.94e-2)" 0.9 0.6 0.4 5.5 0.5 10.5 1.9 1.7 0.7 1.0 0.6 8.3 3.2 1.2 0.4 4.2 0.7 1.3 0.6 0.4 0.5 0.5 1.3 1.1 11.0 0.4 0.3 0.6 1.4 0.5 0.2 6.8 0.5 0.8 9.1 0.3 1.0 0.3 1.0 3.1 4.1 2.4 0.1 2.4 1.8 24.3 0.3 15.7 0.6 0.5 13.3 1.7 1.5 0.5 33.8 16.1 33.4 16.3 4.4 7.8 31.1 54.9 16.5 43.3 43.8 35.4 22.1 20.4 26.8 20.9 18.9 67.7 56.6 22.1 42.3 39.0 22.2 47.7 28.2 30.4 0.4 37.9 28.5 1.7 2.9 30.0 13.5 6.4 22.5 48.5 59.6 55.8 36.6 28.5 54.4 43.6 35.2 69.2 19.0 61.0 49.0 30.7 15.4 45.3 15.4 27.0 23.6 41.4 8.5 39.2 27.0 39.4 9.9 32.8 22.2 48.7 27.2 12.0 65.1 59.8 16.3 78.0 33.5 1.3 0.6 1.7 2.4 1.3 0.6 1.7 2.5 3.2 1.0 1.1 0.6 1.2 1.2 1.8 1.4 0.9 5.9 1.2 0.4 0.5 1.7 0.7 0.4 0.5 0.4 0.3 0.5 0.1 0.3 0.5 0.0 0.0 0.0 0.3 1.9 3.6 1.5 2.0 0.0 0.8 0.1 0.0 0.9 0.0 1.0 0.0 0.0 35.3 1.4 3.0 0.0 0.0 5.7 0.2 0.2 1.0 0.0 16.0 1.6 0.0 67.2 1.3 2.0 0.2 0.0 0.6 2.2 0.2 12.7 0.0 1.2 5.3 2.0 1.6 1.7 5.3 0.6 0.5 0.0 1.0 0.3 0.3 2.1 0.5 0.6 0.1 5.0 0.7 8.2 0.9 1.0 0.0 0.1 0.0 0.0 0.5 0.9 53.6 24.8 3.9 1.6 25.3 1.2 0.1 8.0 2.1 RAD51AP1 PIR51 ENSG00000111247 "RAD51 associated protein 1" Q96B01 12 4538798-4560047 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Meiosis" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.9;lymphoid tissue: 14.4" "Cell type enhanced" "Detected in many" "Early spermatids: 33.4;Erythroid cells: 47.8;Extravillous trophoblasts: 34.1;Hofbauer cells: 40.8;Late spermatids: 68.1;Spermatocytes: 35.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051499 Approved Nucleoplasm Yes Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA051499: AB_2681508" "unprognostic (1.03e-1)" "unprognostic (5.44e-3)" "unprognostic (1.84e-1)" "prognostic unfavorable (9.42e-4)" "unprognostic (6.30e-2)" "unprognostic (5.25e-3)" "prognostic unfavorable (3.53e-4)" "unprognostic (2.15e-2)" "unprognostic (2.26e-2)" "unprognostic (6.29e-3)" "prognostic unfavorable (1.22e-5)" "unprognostic (1.00e-1)" "prognostic unfavorable (4.44e-15)" "unprognostic (2.68e-2)" "unprognostic (2.22e-1)" "unprognostic (6.88e-2)" "unprognostic (3.75e-2)" 0.9 0.8 0.3 4.8 0.4 16.9 2.7 0.4 0.7 0.9 0.3 5.2 5.2 1.2 0.6 3.2 1.0 1.1 0.5 0.3 0.3 0.8 1.8 1.4 8.9 0.4 0.4 0.5 0.4 0.6 0.3 3.8 0.4 1.3 6.5 1.5 1.0 1.0 0.5 3.2 4.8 1.9 0.4 3.4 2.7 6.3 0.4 14.4 1.0 0.6 7.9 1.7 1.3 0.5 37.5 13.0 45.3 22.7 2.7 5.7 53.0 48.2 21.2 52.6 68.9 35.4 35.4 48.6 7.0 10.4 24.7 23.1 31.8 14.5 80.0 38.7 27.0 61.4 21.6 24.8 0.6 56.6 29.9 1.2 1.5 31.6 30.4 7.5 21.4 33.0 39.2 54.4 33.7 13.6 46.5 20.5 110.4 36.3 14.4 46.0 54.3 19.2 16.1 18.3 15.1 16.6 35.9 27.7 11.6 45.5 11.3 32.6 9.5 35.5 36.5 38.8 52.4 7.8 10.0 93.3 13.3 40.0 29.4 0.0 0.5 0.7 0.1 2.3 0.5 3.1 0.4 1.0 0.4 3.4 0.1 0.2 0.0 1.4 2.0 6.9 1.0 0.6 0.3 0.4 0.4 0.7 0.3 0.3 0.4 0.4 0.4 0.4 0.4 0.5 1.4 0.0 0.5 0.7 6.1 5.2 2.3 6.6 1.2 3.1 3.4 5.7 1.4 2.8 4.5 0.0 4.2 20.3 11.3 5.7 0.0 3.0 33.4 3.3 2.9 2.9 2.4 47.8 2.7 2.7 34.1 5.2 6.1 3.6 1.3 22.6 2.5 1.2 40.8 0.0 1.1 6.4 16.2 6.2 5.6 68.1 1.2 10.1 0.0 3.7 6.8 2.7 3.1 0.5 2.4 1.5 0.8 1.5 15.5 1.0 1.2 1.5 0.9 4.8 0.0 2.4 4.2 35.9 25.0 10.0 2.6 4.7 4.6 2.0 14.6 2.7 RAD54L "hHR54, hRAD54, RAD54A" ENSG00000085999 "RAD54 like" Q92698 1 46246461-46278480 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.4;testis: 15.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 7.2;Extravillous trophoblasts: 9.4;Glandular and luminal cells: 8.0;Spermatocytes: 12.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.1" "Lineage enhanced" "Detected in single" "T-cells: 1.1" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA028954, HPA051537" Approved Enhanced Nucleoplasm NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA028954: AB_2672840, HPA051537: AB_2681525" "unprognostic (2.12e-2)" "prognostic favorable (6.67e-4)" "unprognostic (5.12e-2)" "unprognostic (5.36e-3)" "unprognostic (3.24e-1)" "unprognostic (1.08e-2)" "unprognostic (9.75e-6)" "unprognostic (3.91e-2)" "unprognostic (2.17e-3)" "unprognostic (2.95e-2)" "unprognostic (1.77e-4)" "unprognostic (5.58e-2)" "unprognostic (1.11e-16)" "unprognostic (6.76e-3)" "unprognostic (1.66e-1)" "unprognostic (2.67e-1)" "unprognostic (1.74e-1)" 0.5 0.7 3.0 4.1 3.8 8.7 1.0 4.3 3.9 1.3 2.1 3.2 2.0 0.7 0.1 5.4 0.4 0.5 0.7 2.9 2.5 1.4 0.5 1.2 5.5 3.2 3.0 0.5 0.5 0.3 0.4 3.4 3.8 1.0 4.6 0.4 0.9 0.4 1.2 2.3 2.8 1.7 2.8 2.8 1.5 15.6 3.1 15.4 1.8 0.0 8.3 0.8 1.8 3.7 22.2 16.1 46.8 29.1 3.3 2.4 43.9 25.8 11.3 42.8 43.3 33.3 14.2 42.5 19.1 11.0 38.5 22.2 44.6 14.5 36.8 23.7 43.0 53.0 49.7 32.1 0.1 54.0 29.3 1.6 1.2 42.1 12.5 6.9 13.5 49.7 38.2 41.7 23.1 20.4 68.9 60.0 42.5 19.4 25.2 52.8 26.8 19.0 9.4 17.5 22.4 16.3 18.4 25.2 5.7 38.0 9.1 37.7 5.7 43.9 26.1 23.6 43.7 17.6 10.6 46.9 11.5 35.1 18.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.1 0.2 3.0 3.8 4.3 3.9 2.9 2.5 3.2 3.0 3.8 2.8 3.1 3.7 0.0 0.0 0.0 1.0 0.7 0.3 0.7 0.5 1.8 0.0 0.5 0.5 0.8 0.0 0.1 0.0 0.0 4.3 0.4 1.8 0.0 0.3 2.7 2.3 0.8 0.5 0.0 7.2 2.8 0.0 9.4 1.1 0.5 8.0 4.5 5.6 0.4 0.0 2.6 0.0 1.1 1.3 0.0 0.3 0.3 0.7 0.0 0.4 0.0 0.0 0.0 0.0 1.0 1.0 2.9 0.3 0.1 0.0 4.7 0.4 0.4 0.0 0.1 0.0 0.0 0.4 4.0 12.4 5.6 3.1 0.3 1.6 1.1 0.2 2.9 1.0 RANGAP1 "Fug1, KIAA1835, SD" ENSG00000100401 "Ran GTPase activating protein 1" P46060 22 41244779-41286187 "Plasma proteins, Predicted intracellular proteins, Transporters" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Late spermatids: 1717.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004293, HPA050110, HPA062034" Supported Enhanced "Nuclear membrane,Vesicles,Cytosol" Yes Yes 75000 "Cluster 27: Non-specific - Gene expression" "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear membrane" "Vesicles, Cytosol" "CAB004293: AB_2176987, HPA050110: AB_2681018, HPA062034: AB_2684667" "unprognostic (1.30e-2)" "unprognostic (3.16e-2)" "unprognostic (1.66e-1)" "unprognostic (7.97e-2)" "unprognostic (2.57e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (8.28e-3)" "unprognostic (8.09e-2)" "unprognostic (9.87e-2)" "unprognostic (5.84e-2)" "unprognostic (7.56e-2)" "unprognostic (7.07e-3)" "prognostic favorable (5.39e-4)" "unprognostic (2.06e-1)" "unprognostic (2.74e-1)" "unprognostic (2.68e-1)" 27.5 72.9 78.2 26.0 86.0 48.1 29.6 70.8 102.3 34.4 47.7 29.2 18.1 24.9 12.0 79.8 23.6 17.2 45.1 79.5 85.2 43.9 88.0 41.6 30.6 102.7 77.9 32.5 60.9 12.7 57.4 22.8 105.1 39.3 13.2 32.7 38.0 17.6 43.0 96.9 30.6 17.5 68.7 42.3 39.6 178.1 82.0 40.4 34.4 14.2 31.8 34.7 45.4 109.1 228.0 112.2 75.9 77.3 38.8 31.4 85.9 194.5 103.8 182.8 98.4 135.9 71.9 118.0 154.0 137.4 94.8 203.0 135.5 145.4 125.2 95.7 199.2 103.3 115.0 107.9 46.7 171.6 72.5 30.0 69.5 132.2 123.4 67.6 102.1 45.0 127.7 83.3 111.9 186.1 96.3 130.0 84.5 217.6 127.6 118.8 73.4 126.0 72.5 123.7 66.6 44.1 139.1 117.7 71.7 74.6 72.2 64.4 146.5 141.7 138.5 78.6 154.6 60.1 92.8 124.2 99.3 119.3 82.0 2.7 7.6 6.9 8.1 9.0 9.5 5.9 8.2 7.8 5.6 6.4 7.4 5.9 2.0 5.9 12.9 5.9 9.5 8.2 78.2 86.0 70.8 102.3 79.5 85.2 102.7 77.9 105.1 68.7 82.0 109.1 10.9 3.2 20.9 8.5 15.0 23.1 22.2 10.9 18.2 16.0 22.4 16.9 19.6 25.8 9.6 9.2 14.6 22.7 20.3 22.9 3.9 33.3 270.7 21.0 14.7 16.1 25.0 16.6 28.3 20.3 35.3 13.3 25.5 25.1 6.3 74.4 8.9 21.8 16.6 15.2 20.8 19.1 16.2 13.9 20.9 1717.0 14.9 16.8 12.4 5.6 8.9 10.1 14.4 6.0 32.2 39.8 5.7 12.0 25.8 37.4 7.1 13.1 11.4 26.4 0.0 6.8 18.2 25.6 17.7 38.8 31.0 23.7 24.3 42.5 24.8 23.3 RASAL2 nGAP ENSG00000075391 "RAS protein activator like 2" Q9UJF2 1 178094104-178484147 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 28.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 505.8;Inhibitory neurons: 398.4;Microglial cells: 271.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 54.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018805, HPA020453" Enhanced Approved "Plasma membrane,Focal adhesion sites" NA Yes "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Focal adhesion sites" "HPA018805: AB_1856085, HPA020453: AB_1856086" "unprognostic (5.55e-3)" "unprognostic (6.49e-2)" "unprognostic (2.65e-1)" "unprognostic (6.33e-2)" "unprognostic (3.40e-2)" "unprognostic (5.59e-2)" "unprognostic (5.91e-2)" "unprognostic (1.72e-2)" "unprognostic (2.91e-1)" "unprognostic (2.92e-2)" "unprognostic (3.16e-3)" "unprognostic (2.03e-1)" "unprognostic (1.06e-2)" "unprognostic (4.98e-2)" "unprognostic (2.45e-1)" "unprognostic (8.36e-2)" "prognostic unfavorable (2.05e-4)" 10.3 3.6 1.7 2.8 3.2 0.6 8.0 0.0 7.4 7.3 0.1 4.2 2.7 6.1 3.6 17.0 5.5 7.5 13.6 4.3 0.8 5.8 3.0 9.4 1.8 0.0 1.0 3.6 4.6 4.6 5.9 9.4 0.0 5.0 4.4 28.9 6.6 4.4 4.6 7.0 3.4 6.6 0.0 3.2 3.7 8.9 5.1 1.8 5.3 10.0 2.9 5.0 10.5 2.4 30.9 8.9 12.1 4.2 8.6 11.6 17.3 13.2 13.6 11.7 8.5 14.8 15.6 0.0 23.0 13.2 19.7 25.2 10.2 23.0 10.7 0.0 5.0 0.0 9.8 7.1 10.0 4.7 0.5 35.1 5.2 13.4 54.1 13.7 10.3 0.0 1.0 0.0 16.5 3.2 0.0 4.2 10.1 6.4 1.8 0.1 5.2 0.0 7.2 3.6 8.8 4.4 10.9 9.5 9.0 10.8 10.4 5.5 18.9 15.1 15.7 17.2 21.0 6.5 0.1 0.1 13.3 2.4 11.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.7 3.2 0.0 7.4 4.3 0.8 0.0 1.0 0.0 0.0 5.1 2.4 99.8 76.9 12.9 47.3 1.0 15.9 10.0 15.7 8.0 50.7 17.8 11.7 37.4 17.2 18.2 16.5 152.2 15.0 1.0 9.0 5.9 21.8 17.4 33.6 43.0 66.2 34.1 0.0 505.8 12.5 16.4 18.4 17.9 27.6 7.6 19.0 35.3 6.7 16.8 84.1 398.4 15.7 6.1 4.5 21.6 7.3 19.6 16.5 3.6 271.7 8.5 24.7 0.0 154.3 101.3 33.6 5.2 23.0 2.9 32.6 4.9 6.6 34.7 175.5 65.7 22.7 56.9 40.5 34.5 17.8 24.2 41.9 2.3 8.3 12.6 38.2 RASSF1 "123F2, NORE2A, RDA32, REH3P21" ENSG00000068028 "Ras association domain family member 1" Q9NS23 3 50329782-50340980 "Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 116.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 252.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040735 Approved NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA040735: AB_10671692" "unprognostic (5.02e-2)" "prognostic favorable (2.64e-4)" "unprognostic (3.05e-1)" "unprognostic (2.95e-2)" "unprognostic (1.00e-3)" "prognostic favorable (2.60e-4)" "prognostic unfavorable (9.77e-4)" "unprognostic (3.80e-2)" "unprognostic (2.11e-1)" "unprognostic (1.07e-2)" "unprognostic (1.54e-1)" "unprognostic (3.47e-2)" "prognostic unfavorable (8.58e-5)" "unprognostic (4.27e-2)" "unprognostic (2.29e-1)" "unprognostic (1.11e-1)" "unprognostic (9.71e-2)" 50.1 18.9 19.2 23.2 19.5 84.3 46.0 19.6 20.1 44.1 18.1 28.4 15.6 29.7 11.1 26.2 35.4 21.5 47.7 18.4 19.2 39.0 24.7 61.2 39.5 20.8 20.0 31.2 35.3 7.5 22.2 25.8 20.4 31.6 11.6 6.1 30.2 11.8 28.5 38.9 39.6 18.1 20.7 72.3 31.7 38.5 20.4 16.3 29.7 14.3 25.5 32.3 37.4 22.1 37.4 15.1 11.1 18.5 25.0 33.8 16.2 62.5 40.9 52.6 41.8 34.7 27.3 18.0 9.4 67.3 23.6 19.6 23.3 26.1 28.3 44.6 15.2 61.8 51.9 18.4 28.6 61.2 65.2 26.1 18.1 52.0 18.4 15.4 23.7 21.8 26.2 40.7 24.1 13.1 23.3 81.9 14.7 31.2 44.9 19.0 11.4 41.4 15.7 10.8 13.0 23.9 55.6 37.2 41.5 11.2 22.3 59.2 22.9 36.1 27.2 52.0 31.3 16.5 11.7 39.4 20.3 75.6 66.1 252.6 23.3 79.5 77.0 41.5 48.3 44.3 24.6 55.3 24.9 33.6 15.7 37.7 18.4 64.6 59.1 18.5 27.5 42.0 19.2 19.5 19.6 20.1 18.4 19.2 20.8 20.0 20.4 20.7 20.4 22.1 76.6 16.0 8.1 4.6 50.7 73.8 36.3 22.6 34.1 11.6 32.7 22.9 14.3 12.8 14.4 1.8 14.6 27.5 116.1 12.2 5.9 23.1 2.4 16.5 16.3 47.4 16.7 33.2 3.8 26.5 28.1 29.1 27.0 17.6 57.1 9.0 26.0 4.3 38.6 3.3 3.8 19.4 22.4 27.7 43.8 10.4 19.0 28.7 90.7 9.4 23.2 6.1 93.7 2.0 6.0 40.9 17.4 14.7 63.8 24.7 12.1 10.2 7.7 10.1 26.3 19.3 50.4 33.1 11.0 19.2 50.2 16.6 67.2 9.0 15.2 21.3 RBBP8 "COM1, CtIP, RIM, SCKL2" ENSG00000101773 "RB binding protein 8, endonuclease" Q99708 18 22798261-23026488 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "DNA-binding, Endonuclease, Hydrolase, Nuclease" "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 125.9;Spermatocytes: 116.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 36.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039890, HPA052946" Approved Supported Nucleoplasm NA Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" Nucleoplasm "HPA039890: AB_10794756, HPA052946: AB_2681996" "unprognostic (1.55e-3)" "unprognostic (4.10e-3)" "unprognostic (7.89e-2)" "unprognostic (1.01e-1)" "unprognostic (2.44e-1)" "unprognostic (7.28e-2)" "unprognostic (3.60e-3)" "unprognostic (1.87e-1)" "prognostic unfavorable (7.21e-4)" "unprognostic (2.29e-2)" "unprognostic (1.58e-3)" "unprognostic (1.04e-2)" "prognostic favorable (1.71e-5)" "unprognostic (3.91e-3)" "unprognostic (2.42e-2)" "unprognostic (1.01e-2)" "unprognostic (4.48e-1)" 10.1 8.7 6.8 10.0 6.8 18.2 29.4 9.2 11.3 20.9 41.6 14.5 9.3 20.1 23.4 22.1 28.0 12.7 7.0 7.4 9.2 42.2 14.4 13.5 14.0 6.3 7.3 6.4 18.5 22.1 17.5 8.5 6.4 10.8 12.9 6.2 19.5 23.3 2.3 28.5 12.9 16.4 6.2 7.6 13.1 28.7 8.5 32.4 18.2 3.5 17.3 18.3 18.0 7.3 32.9 24.8 36.0 41.9 18.2 19.4 28.2 44.2 31.1 40.3 56.5 45.7 36.3 95.4 19.9 27.9 38.5 67.3 41.2 89.9 78.5 68.3 33.2 41.8 32.0 44.0 22.2 151.5 43.7 13.9 86.0 61.0 105.3 23.6 16.6 65.7 25.0 69.2 41.6 49.1 112.8 50.6 34.2 60.1 41.5 57.6 65.9 58.9 117.4 34.7 84.1 39.8 74.1 22.4 39.0 20.5 129.1 39.4 12.0 107.2 49.3 52.4 78.0 92.9 108.4 105.3 49.1 72.2 58.8 17.0 6.5 3.9 1.2 24.0 0.5 6.6 1.7 2.1 8.2 5.3 0.9 1.5 2.4 7.9 36.7 8.1 4.7 3.8 6.8 6.8 9.2 11.3 7.4 9.2 6.3 7.3 6.4 6.2 8.5 7.3 13.1 35.3 42.8 10.1 22.9 27.4 44.7 125.9 76.8 4.3 22.6 72.6 10.4 35.8 41.9 29.5 4.2 12.7 25.0 14.5 43.0 30.5 17.7 56.0 19.5 14.2 7.7 37.0 20.3 33.0 9.4 13.2 23.0 67.3 66.1 22.3 5.7 16.4 11.7 1.7 15.5 9.3 16.2 11.4 23.5 14.5 6.5 27.5 23.2 8.4 9.0 2.1 4.1 9.5 2.7 44.9 8.6 5.3 53.8 37.5 17.5 26.1 28.2 7.9 0.0 20.4 14.0 116.6 83.4 36.2 19.7 15.2 13.6 9.8 14.9 45.5 RCCD1 MGC14386 ENSG00000166965 "RCC1 domain containing 1" A6NED2 15 90954870-90963125 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 56.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039683, HPA040776" Enhanced Enhanced "Plasma membrane,Cytosol" NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "HPA039683: AB_10794752, HPA040776: AB_10795478" "unprognostic (1.01e-2)" "unprognostic (1.69e-2)" "unprognostic (7.22e-3)" "unprognostic (8.63e-2)" "unprognostic (6.18e-2)" "unprognostic (2.91e-2)" "unprognostic (8.75e-2)" "unprognostic (5.86e-2)" "unprognostic (4.83e-2)" "unprognostic (5.10e-2)" "unprognostic (5.69e-2)" "unprognostic (2.72e-2)" "unprognostic (1.49e-3)" "unprognostic (1.32e-2)" "unprognostic (2.41e-1)" "unprognostic (4.71e-2)" "unprognostic (3.94e-2)" 3.9 8.8 4.1 3.0 4.3 4.6 3.5 5.5 5.2 6.9 5.0 6.3 5.1 5.5 3.5 6.6 6.0 2.0 5.9 4.0 3.6 6.2 6.7 2.6 3.9 3.3 3.2 7.3 9.2 5.2 2.9 2.2 3.7 5.4 4.5 3.1 5.0 2.8 3.8 7.4 4.8 2.8 2.9 4.3 6.7 5.8 3.5 4.7 4.5 1.0 4.7 5.5 5.7 3.4 8.0 11.7 2.7 5.7 6.6 7.8 20.2 9.1 1.6 2.6 2.7 5.6 14.9 28.0 14.2 5.6 0.2 16.8 8.9 2.4 4.3 23.7 18.2 20.3 21.2 8.0 5.5 9.8 7.7 5.8 8.0 2.6 3.6 10.3 4.3 16.2 15.7 18.0 7.8 2.7 11.8 10.2 10.4 9.6 4.8 14.0 13.6 30.4 12.0 3.6 8.8 10.1 15.8 10.0 11.6 14.2 11.5 18.7 6.9 1.6 11.2 6.6 0.4 31.9 14.1 16.9 3.0 21.4 7.7 0.0 0.2 0.0 0.2 0.6 0.5 0.8 0.4 0.7 0.4 0.5 0.8 0.2 0.0 0.5 0.3 0.6 0.6 0.2 4.1 4.3 5.5 5.2 4.0 3.6 3.3 3.2 3.7 2.9 3.5 3.4 6.0 0.0 2.2 7.5 9.7 7.4 11.3 9.0 7.4 6.2 9.9 10.9 8.5 4.3 5.3 7.3 4.2 20.9 5.0 14.9 3.9 8.0 3.1 3.2 8.2 5.0 22.1 56.8 9.6 4.9 18.4 8.0 8.2 5.7 0.0 12.5 4.2 8.5 12.0 0.0 11.3 20.5 6.1 8.1 4.0 6.5 8.7 5.7 5.4 3.7 4.3 11.1 10.3 8.5 2.0 5.0 11.7 7.9 9.4 9.8 17.4 13.7 2.9 2.9 26.3 9.7 9.2 22.2 20.1 17.2 8.9 9.0 4.6 10.2 25.7 7.3 RECQL4 RecQ4 ENSG00000160957 "RecQ like helicase 4" O94761 8 144511288-144517845 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Helicase, Hydrolase" "Cancer-related genes, Cataract, Craniosynostosis, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.4;testis: 22.4" "Cell type enhanced" "Detected in many" "Spermatocytes: 23.5;Spermatogonia: 20.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "CAB017800, HPA025821" Supported Enhanced Nucleoplasm NA Yes "Cluster 32: T-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB017800: , HPA025821: AB_1856168" "unprognostic (5.92e-2)" "unprognostic (1.86e-1)" "unprognostic (2.05e-1)" "unprognostic (1.18e-1)" "unprognostic (9.17e-2)" "unprognostic (3.17e-2)" "prognostic unfavorable (1.91e-4)" "unprognostic (1.12e-2)" "unprognostic (4.12e-2)" "unprognostic (7.53e-2)" "unprognostic (2.65e-2)" "unprognostic (4.26e-2)" "unprognostic (1.12e-3)" "unprognostic (8.82e-3)" "unprognostic (1.74e-1)" "unprognostic (2.24e-1)" "unprognostic (1.34e-1)" 1.7 1.8 3.0 5.8 3.7 25.4 2.0 7.7 7.0 2.9 0.1 4.7 6.0 2.5 0.4 13.3 2.1 2.1 1.8 2.6 1.6 2.5 2.7 2.3 6.8 6.9 2.3 2.7 3.1 0.7 3.1 2.5 7.4 8.6 1.6 1.5 5.8 0.8 2.5 10.1 5.2 1.0 1.7 6.5 3.2 22.4 4.1 7.4 3.4 0.5 2.5 2.5 3.1 3.6 33.7 58.8 27.0 57.1 1.6 2.6 47.1 33.2 5.9 24.2 20.2 58.4 48.4 22.8 21.5 5.6 14.2 40.1 18.0 14.2 6.6 40.3 68.6 82.4 118.5 44.3 0.5 21.2 65.7 3.3 2.1 27.1 5.5 3.4 6.8 45.4 83.3 28.9 8.5 104.1 77.3 56.9 18.8 27.8 69.5 80.0 21.2 37.9 6.7 35.8 52.9 32.0 45.2 37.3 12.1 7.4 45.5 45.7 9.2 38.9 117.4 47.3 62.6 16.0 18.1 39.3 22.4 64.6 39.9 0.0 0.0 0.0 0.2 0.2 0.0 0.3 0.1 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.0 3.7 7.7 7.0 2.6 1.6 6.9 2.3 7.4 1.7 4.1 3.6 0.7 0.0 0.0 2.0 2.2 1.5 0.7 0.9 1.2 2.7 3.7 2.7 1.8 1.5 0.5 0.0 4.2 3.9 1.0 5.9 0.0 0.5 3.9 2.1 0.9 0.7 0.0 6.1 2.0 0.4 8.1 1.8 4.6 2.0 0.0 8.8 0.0 0.7 3.6 0.0 1.6 4.1 0.0 0.6 1.1 7.4 1.2 1.0 0.0 0.0 0.3 0.3 1.0 0.0 0.8 0.3 0.2 1.5 9.1 0.7 0.7 0.5 0.7 1.7 0.0 1.4 1.2 23.5 20.6 6.6 1.0 1.5 1.2 0.5 7.0 0.7 REEP4 "C8orf20, FLJ22246, FLJ22277, PP432, Yip2c" ENSG00000168476 "Receptor accessory protein 4" Q9H6H4 8 22138020-22141951 "Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 89.3;skin 1: 91.0" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 94.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042683 Approved Supported "Endoplasmic reticulum" No Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Endoplasmic reticulum" "HPA042683: AB_2571730" "unprognostic (2.38e-1)" "unprognostic (9.96e-3)" "unprognostic (3.35e-2)" "unprognostic (2.38e-2)" "unprognostic (3.41e-2)" "unprognostic (7.75e-2)" "prognostic unfavorable (4.14e-5)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.91e-1)" "unprognostic (7.15e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.88e-5)" "unprognostic (5.72e-2)" "unprognostic (1.06e-1)" "unprognostic (2.25e-1)" "unprognostic (6.65e-2)" 13.0 8.4 7.0 12.5 8.7 28.4 11.6 8.7 9.7 27.9 7.6 23.8 11.0 9.4 2.1 89.3 11.1 5.6 8.0 6.8 8.2 9.2 12.3 18.0 11.2 10.8 8.5 7.4 12.9 5.0 10.9 14.6 10.5 13.6 10.8 2.1 21.8 6.5 4.1 91.0 16.9 5.9 9.0 33.2 18.0 42.7 9.5 9.9 14.8 2.6 10.2 19.6 49.0 11.5 42.2 79.7 24.9 39.7 10.5 10.6 47.9 36.7 19.2 44.6 40.2 46.7 38.8 53.0 46.8 18.4 38.5 100.3 29.6 59.3 21.9 28.2 37.4 57.4 41.2 46.9 11.8 25.8 77.9 9.8 110.3 33.3 27.5 13.9 27.1 58.1 44.5 158.7 22.6 60.6 63.7 88.9 37.4 58.0 53.3 37.0 22.5 101.8 19.9 40.0 21.7 40.1 30.0 31.7 52.7 16.5 64.3 35.9 30.5 29.2 50.1 66.6 50.3 40.0 33.5 34.6 32.6 54.7 59.1 49.8 54.8 64.1 24.3 53.6 19.6 10.5 21.1 21.1 42.7 4.9 9.7 13.1 15.5 26.3 37.0 16.9 15.4 27.6 7.0 8.7 8.7 9.7 6.8 8.2 10.8 8.5 10.5 9.0 9.5 11.5 6.8 3.2 9.2 4.9 7.9 28.0 15.1 45.5 15.4 6.5 5.8 5.7 1.8 7.2 21.9 12.9 2.1 54.0 13.8 27.3 0.0 21.9 16.0 3.8 4.9 9.2 17.4 48.2 0.7 15.0 50.4 8.1 21.9 5.9 10.2 14.0 15.4 6.6 55.4 0.0 0.6 33.0 22.4 38.8 21.5 9.4 9.0 26.1 3.6 10.3 16.5 1.8 10.3 1.0 2.6 25.6 34.7 8.2 19.3 19.0 19.2 1.9 8.1 1.5 13.1 2.3 9.7 61.0 17.9 41.1 39.2 94.1 13.5 8.9 31.1 24.5 RFC2 "A1, RFC40" ENSG00000049541 "Replication factor C subunit 2" P35250 7 74231499-74254458 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA replication" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 68.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029493 Approved Supported "Nucleoplasm,Golgi apparatus" NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus" "HPA029493: AB_10603991" "unprognostic (1.25e-1)" "prognostic favorable (9.91e-4)" "unprognostic (1.44e-1)" "unprognostic (7.66e-3)" "unprognostic (1.17e-2)" "unprognostic (1.93e-1)" "prognostic unfavorable (6.35e-4)" "unprognostic (2.08e-2)" "unprognostic (5.74e-2)" "unprognostic (2.35e-2)" "unprognostic (5.57e-2)" "unprognostic (2.79e-2)" "prognostic unfavorable (2.09e-7)" "unprognostic (2.22e-1)" "unprognostic (6.65e-2)" "unprognostic (3.61e-2)" "unprognostic (2.59e-1)" 12.2 9.5 10.6 13.4 10.9 27.4 15.5 11.4 11.5 12.6 11.1 13.4 9.0 9.6 8.4 18.6 10.1 8.6 10.1 10.5 10.9 14.7 21.2 11.3 23.5 11.7 11.3 11.3 13.3 11.8 7.9 18.4 11.4 11.5 15.0 8.8 12.2 7.6 18.8 20.3 11.2 12.6 11.5 14.2 13.6 10.0 10.7 20.2 9.2 12.2 30.8 11.5 12.6 11.8 74.3 55.6 65.2 64.6 13.1 15.2 29.4 42.5 46.7 85.2 101.4 62.6 67.3 69.2 11.5 30.7 78.7 49.7 53.3 69.2 87.5 49.6 91.5 42.9 76.4 46.7 10.1 64.6 25.3 15.4 15.9 79.8 55.0 18.5 46.0 63.9 89.4 41.9 66.4 87.2 65.1 124.7 74.1 116.3 47.4 95.0 72.0 85.8 45.7 58.1 52.4 65.5 50.7 94.8 34.7 79.2 68.7 58.0 17.4 83.4 54.9 64.6 96.3 25.1 35.1 120.6 42.4 98.4 89.3 33.4 36.7 27.3 18.0 42.3 18.1 31.6 15.5 16.5 31.9 36.8 19.5 14.3 46.4 42.9 40.1 17.1 23.9 29.1 10.6 10.9 11.4 11.5 10.5 10.9 11.7 11.3 11.4 11.5 10.7 11.8 15.4 12.8 11.1 2.6 19.0 23.8 24.3 24.3 19.9 13.2 12.6 17.4 6.1 5.7 16.5 5.5 2.1 68.6 17.5 12.4 5.9 21.0 2.8 8.1 13.3 13.5 4.8 38.3 3.0 19.0 65.0 17.4 10.7 11.5 23.4 25.1 13.6 14.0 37.7 3.3 2.6 13.1 20.3 14.4 28.2 2.5 8.7 18.2 21.4 1.9 26.3 16.1 23.7 1.5 2.2 13.8 6.9 10.9 17.5 11.0 13.2 13.8 8.8 9.5 6.6 14.6 17.5 33.8 44.6 20.1 17.0 46.1 16.9 12.9 19.1 15.3 RFC3 "MGC5276, RFC38" ENSG00000133119 "Replication factor C subunit 3" P40938 13 33818069-33966558 "Predicted intracellular proteins" "DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 285.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030149 Approved Supported Nucleoplasm,Vesicles No Yes "Cluster 27: Non-specific - Gene expression" "Cluster 63: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Vesicles" "HPA030149: AB_10602921" "unprognostic (3.86e-2)" "unprognostic (5.27e-2)" "unprognostic (1.12e-1)" "unprognostic (1.16e-2)" "unprognostic (5.76e-2)" "unprognostic (3.07e-3)" "unprognostic (3.32e-2)" "unprognostic (4.93e-2)" "unprognostic (9.02e-3)" "unprognostic (4.49e-1)" "unprognostic (6.46e-2)" "unprognostic (4.05e-2)" "unprognostic (5.24e-3)" "unprognostic (4.05e-2)" "unprognostic (1.79e-1)" "unprognostic (5.08e-2)" "unprognostic (2.86e-1)" 5.3 13.8 2.6 12.9 2.4 19.5 12.8 8.7 2.6 5.7 1.7 9.0 8.5 10.6 4.3 6.7 8.3 4.6 6.1 2.7 2.5 5.1 7.4 5.4 24.3 2.7 2.2 7.8 4.8 5.1 2.6 10.8 2.8 6.3 11.6 5.9 5.5 4.1 3.5 7.5 7.9 7.6 3.7 6.6 6.5 12.8 2.6 24.1 6.5 4.4 23.4 5.7 4.6 2.5 49.0 51.1 86.4 69.5 6.5 10.0 47.5 66.6 29.2 85.5 73.7 63.0 72.2 179.8 26.8 25.3 53.2 72.5 111.6 45.9 112.0 71.5 68.9 105.0 54.4 68.0 7.5 127.2 48.3 9.8 5.8 74.5 49.9 14.1 28.9 63.7 75.1 44.2 51.4 56.1 108.8 58.1 104.2 101.2 42.1 40.3 103.4 41.1 25.4 42.7 45.1 79.2 49.4 65.3 33.4 45.7 52.2 66.8 15.5 45.1 49.7 57.1 70.9 24.9 36.7 285.3 32.4 73.7 86.6 1.5 4.4 7.2 3.2 6.1 3.7 5.8 3.9 3.3 6.1 5.5 5.0 4.5 0.9 2.5 5.3 2.5 6.3 3.1 2.6 2.4 8.7 2.6 2.7 2.5 2.7 2.2 2.8 3.7 2.6 2.5 9.3 9.6 6.2 5.9 11.2 12.2 6.9 6.9 7.4 16.5 8.9 10.5 7.5 1.5 8.6 3.7 8.4 29.6 5.1 3.0 3.9 7.3 8.4 7.0 7.9 9.4 6.1 43.8 30.2 8.9 39.3 7.5 3.1 7.7 1.3 17.8 8.9 7.2 11.9 8.4 20.3 4.3 4.1 6.7 4.0 7.9 6.2 6.5 8.8 34.7 6.4 5.4 1.0 33.7 18.0 5.4 1.5 4.5 21.0 2.7 1.1 5.4 3.8 12.2 6.6 7.9 29.8 52.6 43.2 9.2 7.0 16.4 6.6 9.2 10.1 3.3 RFC4 "A1, RFC37" ENSG00000163918 "Replication factor C subunit 4" P35249 3 186789880-186807058 "Plasma proteins, Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 55.7;Spermatocytes: 86.7;Spermatogonia: 50.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004557, HPA049123, HPA058507" Enhanced Enhanced Nucleoplasm NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB004557: AB_2178593, HPA049123: AB_2680642, HPA058507: AB_2683736" "unprognostic (2.45e-1)" "prognostic favorable (7.41e-5)" "unprognostic (2.84e-1)" "unprognostic (1.81e-3)" "unprognostic (1.03e-1)" "unprognostic (6.69e-3)" "prognostic unfavorable (6.75e-7)" "unprognostic (5.29e-3)" "unprognostic (1.15e-2)" "unprognostic (2.34e-3)" "prognostic unfavorable (7.38e-4)" "unprognostic (5.92e-2)" "prognostic unfavorable (2.22e-16)" "unprognostic (1.80e-2)" "unprognostic (4.98e-1)" "unprognostic (6.15e-2)" "unprognostic (2.16e-1)" 7.0 6.0 7.3 19.3 7.6 41.5 13.8 8.9 11.9 8.8 7.4 15.4 10.9 14.1 6.6 11.8 10.8 7.7 9.1 7.5 7.5 7.3 10.7 7.2 31.5 7.3 7.4 15.0 11.0 8.0 5.7 14.5 7.6 7.7 20.4 11.2 8.6 7.0 8.3 11.7 11.7 17.6 7.5 14.3 10.4 22.7 8.1 35.7 7.3 6.7 34.5 7.8 8.2 8.3 167.3 56.2 130.8 83.6 18.8 20.1 103.0 78.9 49.9 123.6 135.8 84.8 77.9 119.5 177.4 38.0 118.0 86.1 116.5 77.5 151.1 180.5 102.5 123.3 86.3 86.3 14.6 131.8 79.5 17.3 27.5 84.9 66.1 27.6 42.0 183.8 97.9 165.4 85.3 79.7 167.2 122.8 116.0 148.1 76.0 129.9 112.5 164.3 44.9 60.7 126.3 63.3 97.3 107.6 90.3 97.6 183.0 123.7 19.6 74.4 93.3 125.8 239.9 91.9 216.9 398.9 65.3 142.8 100.0 0.0 2.8 9.7 11.5 4.2 11.1 13.1 11.4 12.0 5.0 15.1 11.2 10.2 0.6 9.8 14.7 9.6 21.8 7.7 7.3 7.6 8.9 11.9 7.5 7.5 7.3 7.4 7.6 7.5 8.1 8.3 5.1 0.0 2.2 3.3 14.0 6.0 15.3 18.1 5.2 16.1 4.1 8.1 7.5 5.7 9.3 11.0 0.0 43.0 9.7 4.4 5.9 15.3 27.3 5.6 7.0 6.1 1.2 46.3 5.2 16.6 55.7 8.3 6.6 6.0 8.2 25.3 6.1 3.0 23.9 8.4 4.4 7.1 10.2 2.6 4.9 10.0 10.5 6.2 1.8 4.7 12.2 14.9 9.2 2.5 4.3 9.2 4.1 7.9 23.8 3.8 2.8 7.9 7.9 14.4 6.6 10.2 13.1 86.7 50.5 7.9 3.0 11.2 9.6 8.8 13.9 4.7 RHNO1 "C12orf32, HKMT1188, MGC13204, RHINO" ENSG00000171792 "RAD9-HUS1-RAD1 interacting nuclear orphan 1" Q9BSD3 12 2876258-2889524 "Predicted intracellular proteins" "Cell cycle, DNA damage" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 67.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA Yes "Cluster 26: Non-specific - Mitochondria" "Cluster 16: Immune cells - Immune response" "Cluster 5: NTERA-2 - Transcription" "Cluster 12: Non-specific - Cell cycle regulation" "unprognostic (3.90e-2)" "unprognostic (4.86e-2)" "unprognostic (6.48e-3)" "unprognostic (1.86e-1)" "unprognostic (5.15e-2)" "unprognostic (3.59e-2)" "prognostic unfavorable (2.20e-4)" "unprognostic (7.15e-2)" "unprognostic (1.19e-2)" "unprognostic (1.12e-3)" "unprognostic (4.83e-3)" "unprognostic (2.68e-1)" "prognostic unfavorable (5.74e-13)" "unprognostic (1.97e-1)" "unprognostic (1.64e-1)" "unprognostic (2.54e-2)" "unprognostic (4.53e-2)" 5.5 8.8 12.5 13.1 10.9 17.1 12.1 11.3 13.5 13.1 12.2 14.1 11.0 11.5 22.7 17.5 12.2 10.7 7.2 12.5 13.5 9.1 5.2 9.2 19.6 9.7 10.0 15.6 8.7 13.6 12.0 11.6 12.4 13.4 14.5 13.0 12.1 12.7 6.5 14.1 10.1 11.5 8.3 12.8 10.6 11.3 12.2 25.7 16.6 3.9 20.9 12.4 10.6 16.7 42.3 54.2 64.5 32.9 14.8 18.6 67.7 40.7 43.3 51.0 50.1 66.3 91.4 34.5 22.8 42.4 64.2 32.4 43.0 50.9 62.4 138.6 28.2 45.0 25.3 39.6 20.0 50.8 33.4 18.4 32.4 50.3 104.8 36.7 52.5 71.8 41.1 81.2 61.3 60.9 92.8 28.5 149.7 52.8 32.4 61.6 77.7 26.8 41.2 52.3 21.6 32.0 56.1 35.6 30.0 117.7 69.3 47.2 37.1 55.1 83.6 62.6 85.3 18.5 37.9 90.6 25.3 41.8 51.7 23.7 23.3 34.9 23.8 22.0 31.2 27.7 36.4 31.9 26.5 41.9 36.8 24.7 4.8 26.5 23.9 15.8 54.7 25.9 12.5 10.9 11.3 13.5 12.5 13.5 9.7 10.0 12.4 8.3 12.2 16.7 3.8 0.0 5.9 3.3 14.0 7.8 10.0 27.7 6.2 6.8 11.9 13.3 7.6 7.2 10.4 11.0 8.4 40.1 6.5 7.2 23.5 13.9 6.5 8.1 7.0 8.7 10.3 33.2 6.6 8.4 34.0 8.2 7.1 9.0 14.0 17.4 12.5 3.9 31.7 10.1 6.4 16.3 14.2 15.5 8.0 14.6 12.2 10.2 3.6 2.8 32.3 20.4 10.3 3.0 6.5 6.9 9.6 8.6 11.4 18.1 13.2 15.4 6.4 9.8 0.0 3.1 7.5 67.1 46.0 18.8 7.1 21.8 17.3 8.4 17.3 12.5 RMI1 "BLAP75, C9orf76, FLJ12888" ENSG00000178966 "RecQ mediated genome instability 1" Q9H9A7 9 83980798-84004074 "Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 70.0;Late spermatids: 62.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021661 Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nuclear bodies" "HPA021661: " "unprognostic (9.59e-2)" "unprognostic (7.96e-2)" "unprognostic (6.72e-3)" "unprognostic (3.03e-2)" "unprognostic (1.47e-1)" "unprognostic (2.90e-2)" "prognostic unfavorable (8.71e-4)" "unprognostic (2.65e-1)" "unprognostic (3.39e-3)" "unprognostic (1.32e-1)" "unprognostic (5.55e-2)" "unprognostic (2.26e-1)" "unprognostic (1.53e-1)" "unprognostic (3.68e-3)" "unprognostic (3.42e-1)" "unprognostic (2.42e-1)" "unprognostic (9.24e-2)" 2.5 8.3 2.9 6.0 3.2 3.9 4.5 4.6 3.4 3.2 6.0 6.6 6.2 3.5 5.6 4.9 5.8 2.8 3.4 2.4 5.8 4.4 5.8 3.3 10.2 3.3 3.3 4.4 5.8 7.7 3.7 3.6 3.5 4.8 7.4 7.0 6.0 3.1 3.7 5.1 6.8 3.3 3.2 6.4 6.2 8.9 3.8 10.2 6.0 3.9 9.6 3.6 2.4 3.8 25.2 14.9 33.6 12.4 5.5 7.7 33.9 24.1 13.6 20.7 19.4 7.5 17.0 55.4 8.5 12.4 21.7 36.9 22.0 12.3 25.3 29.2 6.1 23.0 12.1 11.8 7.7 42.6 23.1 7.4 7.8 17.6 12.6 6.7 11.1 28.2 16.7 26.3 23.2 18.1 54.4 17.4 31.3 31.6 15.7 47.8 33.9 21.0 10.8 10.4 30.4 19.3 21.3 18.6 9.8 15.4 19.4 20.8 6.6 22.9 14.7 23.2 20.1 11.6 25.6 20.2 14.6 19.7 26.4 14.2 4.5 8.8 1.8 5.5 2.2 2.8 2.1 1.9 7.2 2.6 2.2 2.5 7.8 2.8 6.5 2.2 3.0 2.6 2.9 3.2 4.6 3.4 2.4 5.8 3.3 3.3 3.5 3.2 3.8 3.8 5.4 9.6 5.1 10.1 5.9 2.7 3.2 4.3 4.0 4.1 4.3 3.3 8.5 2.8 9.0 1.8 4.2 7.9 2.1 6.1 5.9 5.5 70.0 13.9 6.5 3.8 6.7 24.4 7.1 3.0 16.2 3.3 8.2 10.2 4.5 9.0 5.0 13.3 8.1 10.1 11.2 9.8 0.0 10.7 4.3 62.1 2.1 7.4 12.4 8.4 8.5 7.7 5.2 26.2 12.6 2.7 5.6 2.2 7.8 4.2 8.9 4.9 11.1 5.2 0.0 3.3 3.4 34.0 22.6 6.9 4.8 4.2 4.4 7.7 10.1 2.4 RMI2 "BLAP18, C16orf75, MGC24665" ENSG00000175643 "RecQ mediated genome instability 2" Q96E14 16 11249619-11381662 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 36.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 123.8;Erythroid cells: 38.5;Extravillous trophoblasts: 34.1;Peritubular cells: 42.5;Spermatocytes: 36.6;Spermatogonia: 51.8;Syncytiotrophoblasts: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 4.2" "Group enriched" "Detected in many" 6 "B-cells: 4.2;T-cells: 1.4" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA040995 Uncertain Supported "Nuclear speckles,Cytosol" NA Yes "Cluster 37: B-cells - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear speckles" Cytosol "HPA040995: AB_10795531" "unprognostic (2.76e-1)" "prognostic favorable (5.69e-5)" "unprognostic (1.17e-1)" "unprognostic (3.09e-3)" "unprognostic (1.69e-2)" "unprognostic (1.80e-3)" "prognostic unfavorable (2.77e-5)" "unprognostic (3.98e-1)" "unprognostic (1.16e-1)" "unprognostic (1.83e-1)" "unprognostic (3.44e-3)" "unprognostic (3.89e-1)" "unprognostic (2.18e-1)" "unprognostic (5.50e-2)" "unprognostic (3.68e-2)" "unprognostic (3.60e-3)" "unprognostic (1.03e-1)" 1.4 1.5 2.2 12.3 2.0 9.9 5.1 1.0 2.2 4.8 0.9 12.5 7.5 2.9 3.9 10.8 2.1 2.2 1.6 2.3 1.3 3.4 4.3 1.9 31.4 1.2 1.3 3.0 1.8 1.3 0.6 19.3 1.2 3.2 14.4 0.5 2.4 2.1 0.9 10.2 8.8 2.3 1.0 3.5 7.0 14.0 1.4 36.8 1.5 0.6 34.9 4.5 4.4 1.8 60.3 39.5 75.2 32.6 3.3 15.8 33.0 35.9 26.8 31.6 51.8 15.4 69.2 83.8 29.1 15.8 35.3 34.4 32.4 32.5 50.5 16.6 30.5 45.3 22.6 102.5 1.3 17.6 19.5 3.7 6.1 14.5 13.3 12.3 17.4 36.2 65.3 63.2 16.5 70.3 60.9 83.1 64.1 82.6 15.7 73.1 81.1 89.3 18.7 38.0 44.1 35.0 28.5 47.4 26.1 43.5 80.4 25.8 5.6 25.1 23.3 49.3 5.0 18.1 30.9 99.3 23.3 57.4 47.2 0.0 0.0 0.4 0.3 0.0 0.0 4.2 0.1 0.0 0.2 1.1 0.8 0.3 0.1 0.1 0.0 0.2 1.4 0.1 2.2 2.0 1.0 2.2 2.3 1.3 1.2 1.3 1.2 1.0 1.4 1.8 1.3 0.0 0.5 0.0 4.5 6.8 5.4 1.4 6.2 0.2 3.4 3.2 1.0 4.3 1.6 7.3 0.0 123.8 0.5 3.3 5.9 2.6 3.0 0.8 2.1 2.8 2.4 38.5 0.0 0.5 34.1 6.4 4.1 2.2 0.0 19.7 1.1 1.1 18.5 0.0 0.0 7.7 0.0 0.8 6.5 5.9 15.8 3.7 3.6 0.0 1.1 0.2 1.0 0.0 0.0 1.0 4.0 42.5 2.4 2.1 1.3 0.4 0.1 0.6 32.9 0.0 2.2 36.6 51.8 11.3 5.4 47.7 1.9 6.5 10.3 7.5 RNF26 MGC2642 ENSG00000173456 "Ring finger protein 26" Q9BY78 11 119334527-119337309 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 66.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA027620 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 85: Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Vesicles, Cytosol" "HPA027620: AB_1856356" "unprognostic (9.23e-3)" "unprognostic (3.54e-2)" "unprognostic (1.36e-1)" "unprognostic (8.68e-3)" "unprognostic (3.40e-1)" "unprognostic (1.07e-2)" "prognostic unfavorable (3.19e-4)" "unprognostic (2.14e-2)" "unprognostic (3.26e-1)" "unprognostic (1.69e-1)" "unprognostic (7.24e-3)" "unprognostic (6.22e-2)" "prognostic favorable (3.45e-6)" "unprognostic (9.61e-2)" "unprognostic (3.50e-2)" "unprognostic (4.41e-2)" "prognostic unfavorable (7.73e-4)" 14.3 15.8 12.7 11.5 12.6 22.0 13.3 13.7 15.1 15.4 10.6 19.2 14.5 23.5 10.3 20.9 16.6 10.5 13.2 12.7 12.5 13.6 23.6 12.4 11.8 15.2 13.1 17.1 13.8 18.5 10.4 14.2 15.5 14.8 12.6 8.4 14.9 18.6 8.5 15.7 17.0 19.0 12.7 14.6 19.1 15.1 14.7 13.3 13.2 7.1 12.8 18.9 14.2 13.1 43.8 47.4 43.4 51.4 41.8 32.8 46.0 46.3 49.7 52.8 41.5 80.6 88.9 38.3 62.5 55.5 80.1 77.2 61.9 69.8 33.0 46.0 34.2 101.0 21.8 67.3 31.9 42.8 40.4 34.3 35.2 66.1 59.0 34.7 40.8 58.1 50.0 58.4 36.9 94.9 39.5 44.3 43.5 50.2 59.8 40.5 44.5 30.4 32.7 31.1 30.8 29.9 37.4 46.8 12.5 41.4 106.1 35.4 27.0 63.5 41.8 33.7 43.0 14.0 24.6 0.4 21.3 71.0 50.6 9.5 21.6 5.6 20.8 19.2 13.4 11.1 15.7 18.4 19.0 16.7 17.5 15.5 1.5 14.0 20.2 11.0 8.7 24.9 12.7 12.6 13.7 15.1 12.7 12.5 15.2 13.1 15.5 12.7 14.7 13.1 5.1 3.2 9.4 1.0 9.1 6.9 13.3 15.4 12.5 9.2 10.9 9.8 0.8 22.8 11.1 11.0 2.1 44.0 6.2 9.3 5.9 20.8 6.6 5.9 7.9 8.6 13.8 18.5 3.2 17.0 66.0 11.5 9.2 5.9 7.6 16.9 11.4 23.4 21.5 5.0 2.9 13.0 8.2 14.8 5.9 8.6 14.0 6.6 1.8 1.0 11.6 11.6 15.5 4.5 2.7 14.1 7.5 17.7 4.3 14.2 15.6 12.5 4.8 9.4 6.6 6.5 10.6 19.9 10.5 14.3 8.5 24.4 8.3 8.8 18.6 9.8 RPL36AL RPL36A ENSG00000165502 "Ribosomal protein L36a like" Q969Q0 14 49618530-49620626 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" HPA077586 Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "Plasma membrane" "HPA077586: AB_2686846" "unprognostic (1.55e-2)" "unprognostic (2.44e-2)" "unprognostic (8.73e-2)" "unprognostic (3.15e-3)" "unprognostic (1.52e-1)" "unprognostic (2.55e-2)" "unprognostic (1.31e-1)" "unprognostic (6.37e-2)" "unprognostic (4.18e-2)" "unprognostic (1.38e-3)" "unprognostic (2.29e-1)" "unprognostic (4.72e-1)" "unprognostic (1.16e-3)" "unprognostic (8.32e-2)" "unprognostic (2.80e-1)" "prognostic favorable (2.83e-4)" "unprognostic (1.00e-1)" 279.7 310.9 234.2 246.4 241.7 404.2 328.6 232.1 349.8 381.8 221.4 331.8 260.5 280.7 492.7 277.4 315.9 162.6 273.2 225.1 244.6 255.3 372.3 240.5 311.9 244.4 237.3 501.3 628.8 220.0 252.9 176.7 240.6 250.8 248.8 102.0 327.5 253.2 378.6 247.6 284.9 197.9 242.0 294.2 360.3 137.6 240.5 283.4 211.2 206.5 377.1 297.8 285.9 246.2 635.8 473.9 330.1 192.6 471.3 649.8 194.9 508.9 569.9 475.4 534.7 499.0 426.1 833.4 474.5 430.3 327.9 443.5 287.6 441.3 554.8 288.1 331.1 521.6 527.5 652.8 595.1 838.8 426.0 667.8 668.2 362.7 485.9 553.7 614.6 367.3 339.5 714.4 372.8 831.7 496.5 752.6 186.0 452.1 482.0 308.6 519.5 449.5 730.7 964.2 290.3 178.1 448.5 350.8 544.1 313.0 762.2 460.1 468.2 291.3 463.0 382.3 399.8 427.6 487.0 842.7 210.5 376.9 283.7 1308.9 603.0 935.1 823.8 582.2 1113.2 959.3 1070.1 1040.5 614.8 729.1 984.7 937.6 654.0 806.3 542.2 1008.3 1096.2 1506.1 234.2 241.7 232.1 349.8 225.1 244.6 244.4 237.3 240.6 242.0 240.5 246.2 453.2 307.7 395.4 11.4 666.4 945.7 1352.2 1151.7 422.3 110.9 674.6 1022.1 662.4 652.0 643.5 312.6 25.0 690.0 778.0 871.5 995.9 739.8 614.3 490.0 431.4 515.5 366.2 535.9 14.1 1371.2 720.9 523.6 381.3 543.7 716.4 369.2 591.8 920.1 778.5 80.8 16.0 793.7 520.8 814.1 1020.0 236.4 725.7 585.0 843.1 22.5 1045.3 368.1 930.0 11.6 22.9 1311.2 1063.8 534.1 853.2 1279.2 1151.2 1194.4 579.1 127.7 486.4 693.6 898.3 364.7 150.2 390.6 839.3 516.3 888.1 355.4 620.5 1412.3 RPS19BP1 "FLJ21770, MGC52010" ENSG00000187051 "Ribosomal protein S19 binding protein 1" Q86WX3 22 39529093-39532761 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042874 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Cytosol" Nucleoplasm "HPA042874: AB_10793988" "unprognostic (2.44e-1)" "unprognostic (1.67e-1)" "unprognostic (7.79e-2)" "unprognostic (5.07e-3)" "unprognostic (1.65e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (3.71e-4)" "unprognostic (1.65e-1)" "unprognostic (5.68e-2)" "unprognostic (8.31e-2)" "unprognostic (7.00e-2)" "unprognostic (6.73e-2)" "unprognostic (1.04e-1)" "unprognostic (6.11e-2)" "unprognostic (1.65e-1)" "unprognostic (2.34e-1)" "unprognostic (4.32e-2)" 98.5 123.0 122.2 43.1 124.5 61.7 94.6 126.7 159.0 73.5 115.9 117.1 43.5 65.5 31.5 94.2 65.6 19.3 114.6 121.2 119.7 123.1 158.5 80.4 48.0 126.5 124.2 68.9 109.6 47.1 66.5 30.2 123.7 108.1 19.2 23.9 94.4 42.8 104.7 80.0 78.3 19.7 124.8 100.5 101.5 65.8 128.4 40.5 96.7 45.4 34.6 99.9 73.7 123.9 94.8 117.6 54.5 80.4 60.7 39.7 110.8 102.0 87.3 92.5 74.0 131.1 62.1 118.9 107.4 64.5 74.8 73.8 87.8 111.3 32.2 163.8 261.5 110.0 105.5 118.0 88.2 166.8 142.3 60.1 83.1 80.3 96.8 49.4 64.9 87.6 128.0 83.8 61.0 108.0 80.6 164.1 95.1 210.9 209.5 127.3 70.0 182.0 99.7 95.8 121.2 66.9 85.8 137.3 203.1 33.6 98.8 134.8 74.0 77.5 168.8 85.7 141.7 140.3 145.4 188.4 103.3 116.8 183.1 126.8 147.4 187.3 133.0 141.6 123.5 159.7 135.1 140.6 122.4 173.9 129.9 132.8 168.7 128.9 119.4 193.1 165.1 138.3 122.2 124.5 126.7 159.0 121.2 119.7 126.5 124.2 123.7 124.8 128.4 123.9 113.6 44.8 51.4 13.1 109.5 137.1 94.3 124.3 84.2 98.0 178.6 205.7 73.8 105.8 83.0 97.5 52.1 152.9 114.7 205.5 217.2 174.9 23.6 68.6 69.8 121.0 142.6 83.5 8.7 192.2 231.9 92.0 76.0 81.6 69.8 62.0 116.0 184.8 204.3 35.3 10.9 207.5 130.2 116.4 233.3 40.3 137.0 110.8 108.5 8.4 147.8 139.1 162.7 5.5 18.7 233.5 202.2 126.0 193.3 206.8 274.9 362.2 54.0 103.7 78.9 74.4 100.9 61.6 138.0 87.6 147.9 131.6 115.2 103.1 165.9 132.4 RPS27A "S27A, Uba80, UBCEP80" ENSG00000143947 "Ribosomal protein S27a" P62979 2 55231903-55235853 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033319, HPA041344, HPA049132, HPA054087" Supported Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA Yes 230000000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Nucleoli, Endoplasmic reticulum, Cytosol" "CAB033319: AB_793618, HPA041344: AB_2677422, HPA049132: AB_2680646, HPA054087: AB_2682373" "unprognostic (7.32e-2)" "unprognostic (1.41e-2)" "unprognostic (1.11e-1)" "unprognostic (3.20e-3)" "unprognostic (2.16e-1)" "unprognostic (9.75e-2)" "prognostic unfavorable (2.26e-4)" "unprognostic (1.39e-1)" "unprognostic (1.65e-2)" "unprognostic (2.46e-1)" "unprognostic (6.89e-2)" "unprognostic (1.70e-1)" "prognostic unfavorable (2.60e-6)" "unprognostic (1.09e-1)" "unprognostic (8.82e-2)" "unprognostic (1.47e-1)" "unprognostic (3.60e-1)" 1440.7 1208.5 1115.0 1077.7 1151.0 2567.0 2511.6 1098.2 1883.7 2166.1 1099.2 1563.5 823.5 1450.9 1105.1 1698.4 1726.7 572.2 943.7 1085.1 1131.6 1254.8 1162.3 1097.1 1955.6 1133.6 1117.0 3146.7 2043.5 730.2 1057.5 872.9 1131.4 1430.2 1045.0 631.9 1387.4 917.9 1089.6 1767.3 1328.6 814.7 1172.6 1719.2 1478.2 405.9 1150.4 1520.4 1201.6 793.7 1774.4 1506.3 1694.7 1157.1 2384.4 1092.2 1412.2 1842.3 1892.6 3200.3 2412.6 1824.5 1779.4 1692.3 1069.1 2073.7 1987.4 3081.3 2833.2 1698.5 1115.0 1784.3 2061.7 2465.1 1981.0 2899.1 2419.0 2693.9 1088.0 2758.1 2705.9 3674.4 1605.2 3166.1 4213.4 1280.5 3401.6 3015.5 2415.9 1959.5 2469.0 2228.9 1937.3 1509.9 2307.6 4328.7 2831.1 2690.2 1710.6 2086.4 3051.2 3173.8 1994.3 1817.4 1546.0 1319.2 1064.4 4071.8 3843.7 2065.9 1811.0 3411.1 2108.9 1351.7 2395.8 1318.7 3006.7 2322.2 1881.5 1867.9 1923.5 3226.7 1392.6 1301.5 1656.9 637.7 2924.2 1530.8 4268.2 4727.8 4504.3 3592.2 2219.0 4232.8 5675.0 4744.3 351.6 3178.7 1388.8 3292.5 3058.2 8225.2 1115.0 1151.0 1098.2 1883.7 1085.1 1131.6 1133.6 1117.0 1131.4 1172.6 1150.4 1157.1 3051.9 1272.4 2321.3 39.8 7158.8 8321.0 8963.0 6850.9 5010.5 446.4 8189.8 10987.6 438.8 3029.7 3486.3 1397.8 214.8 5340.9 5465.1 1499.3 4055.8 3640.9 1050.2 1695.4 3081.0 3385.0 2057.4 3362.1 45.8 7348.0 6754.1 3043.5 1762.0 1917.3 3014.6 3565.0 3729.5 3181.0 3498.7 218.7 47.8 3995.4 2199.2 5051.0 6045.7 1576.9 5081.5 3382.7 3639.2 59.0 6346.8 2229.4 5579.8 29.1 61.0 5045.3 3396.0 2881.2 3458.4 8189.2 3670.3 5961.1 1726.4 760.9 1643.5 5220.3 4020.2 1047.7 863.4 5750.5 8931.2 5390.3 6365.7 3721.9 4717.6 7980.9 RPS7 "eS7, S7" ENSG00000171863 "Ribosomal protein S7" P62081 2 3575260-3580920 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056586 Approved Approved "Endoplasmic reticulum,Cytosol" NA Yes 820000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "HPA056586: AB_2683179" "unprognostic (3.28e-3)" "unprognostic (1.85e-1)" "unprognostic (7.07e-2)" "unprognostic (2.29e-1)" "unprognostic (3.00e-2)" "unprognostic (5.20e-2)" "prognostic unfavorable (5.27e-4)" "unprognostic (6.41e-2)" "unprognostic (6.02e-3)" "unprognostic (7.08e-2)" "unprognostic (5.60e-2)" "unprognostic (6.27e-2)" "prognostic unfavorable (1.34e-8)" "unprognostic (3.70e-2)" "unprognostic (2.48e-2)" "unprognostic (1.68e-1)" "unprognostic (1.55e-1)" 1083.4 764.7 778.0 774.7 787.2 2152.4 2194.5 772.7 1112.6 1124.8 800.2 1044.1 766.0 867.6 1309.0 1281.8 1152.1 642.5 744.5 755.7 779.1 925.4 1082.6 717.6 1622.5 785.1 770.8 2394.6 1624.1 725.0 686.2 939.7 784.8 887.8 1166.3 603.2 1213.7 697.3 906.5 1419.8 866.8 895.3 805.3 964.6 1011.3 396.3 795.7 1665.6 797.7 843.0 1841.7 1038.2 1063.0 798.4 1235.6 1178.5 1778.9 1923.5 1725.8 3754.0 2913.5 1458.3 2527.9 2370.8 1371.5 2053.4 1890.4 4081.0 2369.1 1697.7 1646.1 1321.0 2038.5 2370.0 2077.4 1289.4 2743.3 1496.8 758.2 2998.2 4156.0 2622.8 1489.1 3183.4 3497.5 1475.1 3176.3 2552.1 2816.8 3707.9 2356.3 2015.2 2433.4 1661.0 2930.2 5815.8 2638.6 3679.7 1810.5 2300.9 1812.6 3670.5 2725.7 1487.1 2016.6 3028.5 771.7 2931.1 4670.0 1487.2 1615.3 3727.3 1327.2 1415.1 931.1 987.9 2387.5 2240.1 4420.9 4079.3 1489.6 3113.0 1617.9 337.1 656.8 243.1 808.8 570.7 1192.3 1411.3 1159.2 1036.9 1063.6 1172.7 1254.6 1132.2 129.3 1032.8 553.2 1016.6 1083.5 2065.3 778.0 787.2 772.7 1112.6 755.7 779.1 785.1 770.8 784.8 805.3 795.7 798.4 2544.8 496.8 793.2 28.1 3845.5 3923.3 4252.7 2961.9 3989.5 401.5 4245.2 7977.4 154.5 1720.0 1620.6 647.4 325.2 3627.9 2815.0 730.8 2606.1 2129.9 1517.5 1255.0 3316.9 1997.7 1250.9 2352.4 33.5 3434.0 5702.2 1854.2 1378.2 1489.1 1171.5 2855.2 2067.5 1515.6 2338.1 141.3 37.2 2244.0 929.8 2534.9 3126.0 485.1 2927.6 2110.0 2001.1 50.6 3250.8 1257.2 2634.4 27.6 49.8 2878.9 1747.3 1748.6 2572.7 4420.1 1233.7 4372.3 847.1 741.6 1452.9 1699.5 3261.7 1248.6 775.4 4912.8 5050.7 3716.9 3078.6 3673.3 2604.1 4351.5 RPS9 S9 ENSG00000170889 "Ribosomal protein S9" P46781 19 54200809-54249003 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048746 Approved NA Yes 64000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "HPA048746: AB_2680510" "prognostic favorable (9.23e-4)" "unprognostic (1.11e-1)" "unprognostic (4.84e-2)" "unprognostic (1.15e-3)" "unprognostic (1.22e-2)" "unprognostic (2.82e-1)" "unprognostic (4.61e-2)" "unprognostic (3.12e-1)" "unprognostic (2.58e-1)" "unprognostic (2.09e-1)" "unprognostic (1.04e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.63e-4)" "unprognostic (2.22e-1)" "unprognostic (9.45e-2)" "unprognostic (5.08e-2)" "unprognostic (3.14e-2)" 1846.1 1581.0 641.4 518.8 641.4 1359.3 1991.4 639.9 975.3 2001.5 638.1 1524.9 564.9 1523.5 469.1 2126.8 1633.0 302.8 1353.2 643.2 640.4 1437.6 1647.5 1359.5 682.3 654.2 658.1 3458.6 3439.2 314.2 932.7 325.4 645.0 1662.3 355.4 79.1 1512.6 167.0 1680.6 2686.6 1454.5 368.3 640.7 1812.7 1610.9 455.4 649.9 968.4 1272.0 627.6 652.3 1582.5 1861.8 647.6 500.8 204.0 257.8 695.7 1424.1 1563.5 602.5 440.1 254.9 246.2 124.4 216.2 861.6 899.9 518.5 785.5 398.8 677.4 922.7 1119.2 196.3 505.5 310.3 328.7 42.2 221.0 1293.3 708.5 711.7 2154.8 1199.7 686.8 882.1 838.6 861.4 831.0 452.2 978.5 693.8 148.0 1452.1 2013.6 770.5 636.4 200.7 865.5 406.3 1507.6 1201.0 228.9 532.3 926.3 255.6 749.5 1308.2 304.6 1003.0 2054.0 249.1 425.4 652.4 545.4 725.2 748.9 663.0 773.2 638.7 752.2 525.7 178.8 847.5 163.1 533.1 712.2 877.4 1075.6 917.4 673.0 741.2 1129.0 1237.5 1060.6 534.1 658.8 677.2 1018.9 627.1 2882.7 641.4 641.4 639.9 975.3 643.2 640.4 654.2 658.1 645.0 640.7 649.9 647.6 1501.4 458.3 1166.6 22.2 3076.3 6471.6 6044.0 4452.4 2423.9 346.2 6390.8 6524.1 198.1 1996.0 1877.7 886.5 175.2 2267.8 2511.4 1539.2 2488.7 1954.7 794.3 1011.6 2061.6 2294.9 1974.5 1549.2 13.6 5626.0 4374.8 1874.4 911.8 1416.2 838.2 2875.5 2494.0 2045.6 2693.9 175.0 14.6 3345.8 1377.3 3888.3 5294.3 1889.2 2872.7 2675.0 3283.5 25.3 3499.1 1219.7 2250.3 16.6 45.8 2925.9 2828.6 1518.0 1474.4 5077.4 3010.2 3183.8 786.3 682.9 1051.8 3030.1 2744.3 526.5 484.2 2627.6 7500.0 2470.4 2489.3 2886.3 3908.4 5842.9 RRM1 ENSG00000167325 "Ribonucleotide reductase catalytic subunit M1" P23921 11 4094707-4138932 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA replication" "Allosteric enzyme, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 102.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022093, HPA057265, HPA064297" Enhanced Supported Cytosol NA Yes 140000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "CAB022093: , HPA057265: AB_2683386, HPA064297: AB_2685236" "unprognostic (4.47e-2)" "unprognostic (1.73e-2)" "unprognostic (1.99e-3)" "unprognostic (3.65e-1)" "unprognostic (2.83e-1)" "unprognostic (2.19e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (1.31e-2)" "unprognostic (3.43e-2)" "unprognostic (6.90e-2)" "unprognostic (1.06e-3)" "unprognostic (4.21e-2)" "unprognostic (6.88e-3)" "unprognostic (9.20e-3)" "unprognostic (6.16e-2)" "unprognostic (8.41e-2)" "unprognostic (9.93e-3)" 16.6 21.2 5.1 24.8 5.3 32.8 22.7 7.1 6.1 16.9 4.7 25.7 19.3 16.2 10.1 26.5 15.5 11.8 16.4 5.1 5.7 13.4 18.4 12.8 34.4 6.1 5.5 16.4 14.6 24.7 7.1 20.4 6.6 18.5 29.4 23.6 14.7 16.0 30.3 36.1 20.2 20.1 6.2 13.0 17.6 17.9 5.1 56.7 15.6 30.0 45.2 15.6 18.9 6.2 221.6 117.8 188.4 110.0 28.4 56.2 73.0 198.0 98.2 220.7 225.9 106.8 163.8 237.4 47.0 100.1 95.9 173.0 176.9 143.2 259.3 117.3 187.9 121.0 159.8 83.1 11.2 208.9 84.6 26.6 37.8 121.7 86.4 48.3 107.8 140.1 161.1 107.3 186.8 99.6 246.7 41.9 118.2 152.2 119.2 196.1 147.0 84.3 59.4 61.8 159.8 88.1 175.1 104.8 30.0 75.8 102.8 71.4 62.3 203.4 106.0 206.9 147.4 70.3 103.5 252.5 114.1 137.6 130.3 8.3 4.0 4.5 11.3 11.2 21.1 9.2 22.3 16.6 7.3 5.2 17.2 15.0 0.0 10.5 15.6 4.4 41.7 10.3 5.1 5.3 7.1 6.1 5.1 5.7 6.1 5.5 6.6 6.2 5.1 6.2 12.4 19.2 14.4 4.9 17.0 33.4 26.8 31.0 17.6 15.6 15.1 14.4 33.5 14.3 24.7 18.4 6.2 62.8 14.9 13.3 7.9 25.6 69.9 11.5 14.5 15.7 18.0 81.2 11.2 22.2 62.5 22.0 20.4 13.9 7.0 27.3 10.8 15.0 28.3 18.5 12.0 25.0 16.2 11.7 10.3 83.9 13.1 13.9 10.6 6.5 10.7 24.0 5.2 12.1 11.9 15.8 10.4 16.6 31.3 10.1 12.5 8.4 15.5 22.7 13.1 19.5 27.1 102.8 63.1 36.5 29.0 39.7 23.2 18.1 34.3 20.6 RRM2 "C2orf48, FLJ25102" ENSG00000171848 "Ribonucleotide reductase regulatory subunit M2" P31350 2 10120698-10211725 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "DNA replication" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 44.2;esophagus: 18.4;intestine: 19.7;lymphoid tissue: 58.1" "Group enriched" "Detected in many" 4 "Erythroid cells: 214.0;Extravillous trophoblasts: 254.1;Plasma cells: 248.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056994 Enhanced Supported Cytosol Yes Yes 13000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA056994: AB_2683304" "unprognostic (2.10e-2)" "unprognostic (1.62e-1)" "unprognostic (6.40e-3)" "unprognostic (4.42e-3)" "unprognostic (5.70e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (1.39e-5)" "unprognostic (1.04e-3)" "unprognostic (6.67e-3)" "unprognostic (4.53e-2)" "prognostic unfavorable (1.62e-4)" "unprognostic (5.11e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.05e-2)" "unprognostic (2.24e-1)" "unprognostic (1.38e-1)" "unprognostic (2.09e-2)" 1.5 1.3 0.3 12.4 0.3 44.2 2.9 0.5 0.4 3.0 1.9 14.2 9.4 2.2 0.7 18.4 0.8 1.1 0.5 0.3 0.3 0.9 3.2 2.4 35.5 0.4 0.4 0.3 1.1 0.3 0.2 4.6 0.4 0.9 19.7 0.2 2.1 0.5 0.1 3.7 7.5 6.1 0.3 11.1 6.0 2.9 0.8 58.1 0.9 0.1 37.6 6.0 4.6 0.5 110.2 25.0 127.1 49.9 7.4 22.5 116.8 209.2 128.6 170.2 187.9 70.8 59.1 114.4 9.5 88.6 151.1 55.0 188.0 136.6 198.0 210.7 41.8 146.3 52.1 105.1 0.8 146.7 87.4 8.1 3.4 234.6 16.2 27.7 103.3 110.4 63.4 328.6 214.3 57.1 167.3 90.9 83.0 133.3 103.6 87.6 187.0 67.8 87.1 62.7 67.7 56.2 198.0 116.6 17.3 51.8 69.2 31.4 57.6 93.1 125.1 66.9 289.6 212.1 184.9 195.9 51.0 134.4 107.7 0.3 0.1 0.1 1.2 0.0 0.0 0.1 0.3 0.8 0.1 0.1 0.1 0.4 0.4 0.8 0.0 0.1 0.2 0.2 0.3 0.3 0.5 0.4 0.3 0.3 0.4 0.4 0.4 0.3 0.8 0.5 0.2 3.2 1.5 0.0 25.0 10.5 3.0 9.2 1.2 0.0 3.9 4.4 1.4 1.5 2.3 0.0 0.0 42.3 5.6 12.9 1.9 1.2 3.9 2.2 3.5 4.2 0.0 214.0 0.1 0.0 254.1 11.2 11.7 3.6 5.7 12.2 3.9 3.7 47.9 0.0 0.0 26.9 2.0 7.2 8.8 6.8 0.3 5.0 0.0 1.0 0.0 0.0 7.2 0.0 0.0 0.5 0.3 0.4 248.0 1.5 2.4 2.1 4.6 0.0 0.0 0.2 14.6 22.9 34.0 51.5 1.6 48.7 11.9 1.2 36.7 5.6 RUSC1 NESCA ENSG00000160753 "RUN and SH3 domain containing 1" Q9BVN2 1 155320894-155331114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 82.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028510, HPA029922, HPA029923" Approved Enhanced Cytosol NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA028510: AB_10599847, HPA029922: AB_10611390, HPA029923: AB_10602288" "unprognostic (1.98e-1)" "unprognostic (2.82e-1)" "unprognostic (2.36e-1)" "unprognostic (1.50e-1)" "unprognostic (5.25e-2)" "unprognostic (2.52e-1)" "prognostic unfavorable (7.78e-6)" "unprognostic (1.42e-1)" "unprognostic (1.38e-1)" "unprognostic (1.73e-1)" "unprognostic (8.29e-2)" "prognostic unfavorable (2.65e-4)" "prognostic unfavorable (9.24e-6)" "unprognostic (7.59e-2)" "unprognostic (4.25e-2)" "unprognostic (2.05e-2)" "unprognostic (1.40e-1)" 27.0 26.6 42.0 11.6 40.7 12.8 23.2 39.9 66.0 38.0 11.3 39.2 21.6 28.8 8.7 49.5 24.8 16.8 28.8 38.9 41.1 32.1 12.6 23.7 10.7 55.2 34.0 27.5 22.5 11.7 45.0 18.2 53.2 32.1 22.9 11.9 32.0 20.3 14.1 37.3 29.9 18.6 28.3 18.0 27.3 6.6 41.4 18.6 19.3 13.3 11.3 26.6 39.2 41.0 70.4 43.5 24.5 36.4 29.6 32.1 47.2 32.7 20.8 42.2 47.1 50.1 45.2 13.7 24.4 33.2 24.2 95.1 38.3 47.4 18.2 18.8 48.8 19.8 44.7 26.6 24.5 19.9 32.9 33.0 29.3 42.5 14.6 20.4 43.9 29.7 30.5 9.4 36.9 133.4 25.0 25.3 48.4 128.4 68.3 33.6 17.1 24.3 40.3 52.7 25.2 40.5 27.6 76.9 16.8 39.8 114.8 33.6 20.2 54.0 44.4 51.4 65.8 7.4 18.0 8.6 38.2 26.5 15.0 5.8 8.0 4.0 6.3 9.8 7.2 3.6 5.1 6.4 8.8 1.5 2.8 6.0 1.1 3.3 25.2 8.4 5.5 5.4 42.0 40.7 39.9 66.0 38.9 41.1 55.2 34.0 53.2 28.3 41.4 41.0 18.2 9.6 12.7 4.9 8.0 28.0 20.1 29.5 22.8 16.9 21.3 19.3 10.2 15.7 27.9 18.4 6.2 30.8 14.8 82.2 23.5 22.4 0.4 9.9 14.7 20.0 15.6 14.5 23.8 17.7 76.6 19.1 25.5 23.6 8.2 9.8 16.4 7.8 21.0 37.0 30.5 51.7 18.3 12.8 20.3 0.5 18.3 11.9 19.6 6.5 11.7 13.4 15.5 7.1 8.2 25.6 43.7 18.0 8.4 29.4 51.8 27.9 10.4 7.0 19.7 12.7 22.2 2.3 8.9 41.4 34.9 38.0 15.2 6.7 40.1 26.0 SAPCD2 "C9orf140, p42.3" ENSG00000186193 "Suppressor APC domain containing 2" Q86UD0 9 137062127-137070557 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.1;esophagus: 8.5;skin 1: 6.2" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 10.8;Oligodendrocyte precursor cells: 29.7;Undifferentiated cells: 12.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 122.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA044154 Approved Supported Nucleoplasm,Nucleoli,Cytosol NA Yes "Cluster 27: Brain & Skin - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Nucleoplasm, Nucleoli" "HPA044154: AB_10959464" "unprognostic (3.68e-2)" "unprognostic (9.85e-2)" "unprognostic (1.13e-1)" "unprognostic (1.11e-1)" "unprognostic (2.80e-2)" "unprognostic (1.27e-1)" "unprognostic (5.42e-8)" "prognostic unfavorable (5.88e-4)" "unprognostic (8.33e-2)" "unprognostic (7.47e-2)" "unprognostic (1.22e-2)" "unprognostic (1.45e-1)" "unprognostic (9.83e-7)" "unprognostic (4.37e-3)" "unprognostic (4.62e-1)" "unprognostic (3.82e-2)" "unprognostic (1.35e-2)" 0.5 0.3 6.9 2.4 5.1 2.0 1.3 4.7 5.4 1.2 1.3 3.7 4.3 0.4 0.0 8.5 0.3 0.2 0.2 5.4 4.5 1.2 0.2 0.5 2.7 7.1 6.8 0.1 0.4 0.0 0.5 0.9 5.7 3.1 1.8 0.1 4.1 0.1 0.1 6.2 4.3 0.4 5.0 2.2 2.4 0.5 6.8 2.3 0.3 0.0 2.5 0.4 2.3 7.0 52.1 27.5 10.7 32.0 0.3 0.7 57.1 8.4 5.7 8.8 4.1 52.5 23.2 53.8 26.5 4.1 8.2 72.3 33.6 9.7 2.0 37.4 38.9 23.6 32.7 59.6 0.2 27.0 39.2 0.1 1.5 3.0 5.8 2.3 14.4 27.1 33.1 23.7 2.6 122.1 7.8 72.7 19.9 119.2 61.9 82.9 40.7 60.1 10.9 14.8 55.2 32.7 32.2 89.1 12.2 2.4 71.9 51.1 9.4 7.9 26.6 24.0 41.9 8.2 25.5 26.3 18.4 31.8 25.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.9 5.1 4.7 5.4 5.4 4.5 7.1 6.8 5.7 5.0 6.8 7.0 0.5 0.0 0.0 0.7 1.9 4.2 0.7 0.5 0.6 0.2 5.0 5.2 1.3 0.0 1.1 0.0 0.0 2.8 1.6 5.4 1.9 0.3 0.0 1.6 0.8 0.9 0.0 3.6 0.2 0.0 3.5 1.1 6.1 6.0 0.0 3.3 1.4 0.0 3.1 0.0 0.2 10.8 0.0 2.8 1.5 0.1 0.0 2.2 0.0 0.0 1.5 0.5 0.0 29.7 5.6 0.6 4.0 0.0 1.8 2.1 0.5 0.0 0.1 0.6 0.0 0.2 1.0 0.0 1.4 5.8 2.7 0.5 1.3 0.6 12.1 1.1 SCD "FADS5, SCDOS" ENSG00000099194 "Stearoyl-CoA desaturase" O00767 10 100347233-100364826 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 1233.7;brain: 839.9;liver: 583.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 389.6;Granulosa cells: 187.3;Hepatocytes: 840.3;Oligodendrocytes: 451.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "ASC diff: 2534.2;CAPAN-2: 1824.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012107, HPA063921" Approved Enhanced "Endoplasmic reticulum" No Yes "Cluster 7: Monocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "HPA012107: AB_1856610, HPA063921: AB_2685154" "unprognostic (2.10e-1)" "unprognostic (2.62e-3)" "unprognostic (7.86e-2)" "unprognostic (5.19e-2)" "unprognostic (1.24e-1)" "unprognostic (6.16e-2)" "unprognostic (1.13e-1)" "unprognostic (3.88e-2)" "unprognostic (6.53e-2)" "unprognostic (2.72e-1)" "unprognostic (1.47e-1)" "unprognostic (1.69e-1)" "prognostic unfavorable (7.56e-5)" "unprognostic (7.18e-2)" "unprognostic (3.27e-1)" "unprognostic (4.73e-2)" "prognostic unfavorable (7.79e-5)" 1233.7 131.2 408.7 25.7 525.8 23.0 261.5 535.7 522.1 43.2 156.6 42.9 93.1 15.4 25.5 107.8 5.0 28.7 47.1 349.1 457.5 18.5 583.8 142.8 17.2 775.0 508.9 49.6 22.6 79.5 10.3 19.9 637.8 100.1 39.7 17.9 112.6 11.2 6.1 27.0 36.0 15.9 574.4 15.3 25.2 51.8 538.7 18.4 13.0 7.2 21.0 22.5 41.9 839.9 411.2 373.3 777.6 536.4 2534.2 1449.4 158.2 43.4 948.3 101.6 536.6 323.8 1824.4 173.3 33.7 102.2 461.8 716.4 433.7 1549.5 88.9 59.4 179.6 97.5 219.3 653.4 488.4 136.9 100.9 795.5 459.4 395.0 688.9 273.1 196.2 375.3 275.4 513.3 41.7 646.8 155.9 163.3 270.7 120.7 106.3 72.6 287.4 550.4 443.8 455.3 48.9 185.3 85.8 399.7 834.9 224.2 447.7 291.3 79.0 10.0 115.9 9.1 89.8 141.4 81.5 262.9 184.4 416.0 65.9 0.0 0.8 0.0 1.4 1.6 2.3 0.6 0.5 0.7 2.7 0.9 0.4 1.3 0.1 1.4 0.0 1.5 0.0 1.2 408.7 525.8 535.7 522.1 349.1 457.5 775.0 508.9 637.8 574.4 538.7 839.9 3.8 54.5 389.6 34.0 15.7 3.7 4.5 121.8 0.6 6.5 16.1 6.2 11.2 28.6 66.2 0.0 6.2 3.0 4.7 21.5 0.0 14.6 52.6 13.9 9.0 12.5 25.8 15.8 4.8 67.9 71.7 15.9 25.0 26.9 6.3 187.3 32.9 840.3 34.1 26.9 5.2 16.4 52.9 113.5 4.2 93.0 3.7 21.2 58.7 8.4 10.2 11.9 2.1 18.6 451.5 29.6 2.7 1.5 3.7 31.4 16.2 4.9 31.0 6.2 0.0 3.6 25.7 2.0 1.2 26.7 2.3 17.4 6.6 97.8 38.9 8.2 SCLT1 "FLJ30655, hCAP-1A" ENSG00000151466 "Sodium channel and clathrin linker 1" Q96NL6 4 128864921-129093600 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Astrocytes: 110.0;Excitatory neurons: 111.1;Inhibitory neurons: 116.0;Oligodendrocyte precursor cells: 109.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 66.0" "Group enriched" "Detected in all" 5 "granulocytes: 66.0;monocytes: 31.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036560, HPA036561" Approved Uncertain Microtubules,Cytosol NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Microtubules, Cytosol" "HPA036560: AB_2675190, HPA036561: AB_10673658" "unprognostic (2.15e-1)" "unprognostic (2.01e-1)" "unprognostic (1.62e-2)" "unprognostic (3.77e-2)" "unprognostic (5.05e-2)" "unprognostic (9.18e-2)" "unprognostic (1.33e-3)" "unprognostic (1.64e-2)" "unprognostic (1.94e-2)" "unprognostic (4.99e-2)" "unprognostic (3.86e-1)" "unprognostic (3.09e-2)" "unprognostic (5.34e-4)" "unprognostic (6.54e-2)" "unprognostic (2.70e-1)" "unprognostic (6.05e-2)" "unprognostic (8.92e-2)" 3.6 3.0 3.7 6.4 4.5 14.4 3.5 7.4 4.8 3.7 0.9 3.7 4.3 3.5 2.2 3.9 3.1 4.6 3.6 2.4 2.8 2.7 3.5 3.5 7.3 4.5 4.3 4.5 3.3 2.9 2.9 4.6 3.5 2.4 4.4 2.9 2.6 2.7 1.5 3.2 3.4 3.6 4.7 7.5 3.5 4.9 5.3 8.8 3.0 1.8 6.7 4.4 3.4 3.9 19.9 5.3 18.8 12.4 6.5 10.5 10.3 16.5 14.8 17.8 16.3 5.7 17.1 17.0 10.4 9.3 12.4 7.4 12.5 12.2 18.5 38.9 10.0 22.7 10.2 6.5 8.9 27.1 17.0 6.7 4.3 14.2 14.2 8.5 14.0 8.6 25.7 39.8 15.6 8.8 20.8 13.0 8.4 14.2 10.5 12.2 19.2 10.6 11.4 5.5 28.1 8.2 12.7 11.5 11.1 8.2 6.8 10.8 13.2 14.5 17.6 19.7 22.3 19.3 15.5 29.0 8.1 29.7 22.2 18.3 16.9 36.8 3.8 24.6 2.2 3.9 2.6 2.7 9.5 3.7 2.5 3.4 66.0 10.2 31.1 4.4 3.7 6.5 3.7 4.5 7.4 4.8 2.4 2.8 4.5 4.3 3.5 4.7 5.3 3.9 16.1 12.8 9.8 110.0 18.0 11.1 8.9 5.8 8.0 15.2 6.1 7.4 21.2 15.7 9.0 1.8 29.2 13.8 34.8 9.1 3.9 6.5 63.2 20.3 18.4 11.9 5.4 9.0 111.1 6.3 21.5 16.3 28.1 14.3 12.0 16.5 9.3 1.6 13.3 16.8 116.0 8.1 8.2 21.6 18.0 51.8 10.8 28.4 8.8 87.1 33.8 8.9 82.4 109.1 90.5 9.0 9.8 9.1 24.0 2.7 8.2 3.1 16.7 21.6 13.1 14.4 16.5 19.6 12.1 13.1 13.9 9.3 21.2 30.5 10.6 5.6 SEC23B "CDA-II, CDAII, CDAN2, HEMPAS" ENSG00000101310 "SEC23 homolog B, COPII coat complex component" Q15437 20 18507520-18561415 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008216, HPA069974" Uncertain Supported Vesicles NA Yes 16000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA008216: AB_1079895, HPA069974: AB_2686223" "unprognostic (4.47e-2)" "unprognostic (2.67e-2)" "unprognostic (3.52e-1)" "prognostic favorable (8.25e-4)" "unprognostic (1.24e-1)" "unprognostic (1.33e-1)" "unprognostic (5.44e-3)" "unprognostic (6.01e-2)" "unprognostic (1.39e-1)" "unprognostic (8.75e-2)" "unprognostic (1.97e-1)" "unprognostic (9.97e-2)" "unprognostic (3.91e-2)" "unprognostic (1.72e-2)" "unprognostic (4.26e-2)" "unprognostic (2.81e-2)" "unprognostic (8.21e-2)" 19.6 38.3 18.7 32.0 27.1 36.0 37.8 24.7 25.9 36.2 27.4 31.6 23.8 17.2 53.8 28.4 29.5 23.1 8.5 19.5 22.4 37.4 30.6 29.7 30.5 27.2 23.8 16.9 57.1 50.6 32.6 24.2 27.2 34.8 32.7 40.7 70.9 35.9 4.1 18.2 23.3 18.5 24.5 25.5 38.2 34.8 23.2 27.6 59.5 6.2 38.0 30.5 12.6 38.9 85.0 93.9 49.8 48.7 32.3 36.6 116.0 69.8 45.3 80.0 68.7 84.9 73.8 37.5 44.9 50.4 107.0 88.5 88.5 120.7 86.2 47.5 43.1 64.9 35.6 130.6 70.5 90.2 78.7 28.0 71.8 118.0 151.4 47.6 50.6 34.0 74.8 82.4 55.1 90.7 59.8 49.5 48.0 118.9 101.6 62.4 77.7 122.1 83.0 85.6 78.8 58.0 83.6 188.9 80.6 62.6 82.3 94.4 45.3 53.1 29.8 58.4 87.1 104.2 155.9 60.1 45.3 47.8 74.4 147.9 94.1 106.0 57.2 95.6 78.7 67.2 56.8 61.4 107.9 61.2 51.3 54.0 48.0 78.8 94.9 80.7 75.4 103.7 18.7 27.1 24.7 25.9 19.5 22.4 27.2 23.8 27.2 24.5 23.2 38.9 8.5 16.0 43.5 15.3 24.7 11.5 21.0 34.3 10.2 21.0 21.5 15.6 3.0 20.0 42.5 31.3 16.7 34.3 36.0 26.2 58.7 36.1 95.6 25.4 12.4 11.3 19.7 7.4 17.9 33.4 30.0 11.7 25.0 31.3 15.9 13.6 11.0 25.6 42.9 13.5 20.5 34.7 26.4 38.7 21.0 11.3 14.3 30.3 23.2 15.0 33.1 23.9 9.2 23.1 27.0 31.8 24.2 10.5 59.0 30.1 11.8 53.2 45.4 20.4 19.7 12.4 12.2 48.7 22.1 15.8 14.2 65.8 21.0 16.0 21.5 28.3 SERF2 "4F5REL, FAM2C, H4F5rel, HsT17089" ENSG00000140264 "Small EDRK-rich factor 2" P84101 15 43777087-43804427 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056613 Uncertain Nucleoplasm,Nucleoli NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Nucleoli "HPA056613: " "unprognostic (3.29e-1)" "unprognostic (7.29e-2)" "unprognostic (1.13e-3)" "prognostic favorable (5.33e-4)" "unprognostic (1.40e-1)" "unprognostic (3.91e-2)" "unprognostic (6.06e-2)" "unprognostic (1.61e-1)" "unprognostic (1.13e-1)" "unprognostic (2.50e-1)" "unprognostic (3.04e-1)" "unprognostic (1.36e-1)" "unprognostic (3.37e-2)" "unprognostic (2.84e-1)" "unprognostic (3.35e-2)" "unprognostic (2.76e-2)" "unprognostic (9.42e-2)" 760.6 1067.4 704.4 446.7 726.4 944.9 619.4 750.2 906.3 650.8 1027.1 728.4 443.4 509.9 776.2 887.9 456.8 469.4 1187.9 698.1 712.2 1002.2 1328.7 700.8 686.4 737.1 725.3 474.3 795.1 490.9 569.3 484.2 734.7 794.5 631.9 72.8 823.7 312.8 636.9 631.1 593.2 507.4 739.4 745.3 784.3 400.2 759.4 450.7 706.6 723.6 628.9 595.0 634.1 758.8 497.5 770.8 573.8 792.9 1963.2 1431.3 438.9 844.8 1042.5 540.4 682.7 991.5 470.0 250.4 694.7 1429.2 698.7 641.1 454.6 623.8 271.1 699.6 526.2 610.9 1074.9 1936.8 934.7 581.8 1235.8 1349.9 810.5 425.8 452.1 836.1 783.5 680.7 630.2 1593.5 1067.4 1441.8 758.6 1337.2 501.5 1849.7 885.1 743.9 382.6 1147.2 1462.5 1695.7 450.6 481.1 458.9 1871.5 463.9 488.4 1574.7 2363.9 682.9 920.0 469.0 1409.4 669.3 593.3 886.2 1837.8 989.2 1032.8 980.4 4033.8 5391.9 5884.9 2716.6 5055.2 2481.3 3853.8 2938.5 2784.5 4649.4 3901.8 2713.3 2731.7 3154.6 2568.8 4495.9 6486.5 3793.5 12856.7 704.4 726.4 750.2 906.3 698.1 712.2 737.1 725.3 734.7 739.4 759.4 758.8 1269.2 506.4 789.0 0.0 1149.8 1151.3 1379.1 3393.0 861.6 53.9 2373.1 2483.2 2229.8 1338.2 2099.5 1736.1 54.2 2660.9 1475.6 2388.2 3897.3 1707.6 576.8 1243.6 1343.1 1283.3 1167.5 1310.8 0.5 2255.2 3410.2 1489.3 1403.7 1261.0 785.9 775.2 1532.4 2884.5 3545.2 47.1 0.5 2862.6 2278.6 2262.1 2298.5 319.2 1225.3 2102.8 1817.8 0.0 2626.4 544.5 1881.6 1.5 0.3 1804.7 2363.9 992.2 1546.7 2188.9 3013.2 5083.6 1950.6 148.4 604.8 680.1 1737.3 750.2 381.1 1725.5 1556.5 3275.8 1216.9 1446.6 2042.5 2819.5 SERPINH1 "CBP1, CBP2, colligen, HSP47, SERPINH2" ENSG00000149257 "Serpin family H member 1" P50454 11 75562056-75572783 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Stress response" Chaperone "Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 473.6;Endometrial stromal cells: 273.3;Extravillous trophoblasts: 342.1;Fibroblasts: 287.6;Smooth muscle cells: 295.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebral cortex: 291.0" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 1018.3;fHDF/TERT166: 1215.2;HHSteC: 1029.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004441, HPA029198" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA Yes 920000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB004441: AB_627757, HPA029198: AB_10601712" "unprognostic (3.80e-1)" "prognostic unfavorable (2.10e-4)" "unprognostic (5.93e-2)" "unprognostic (2.81e-3)" "unprognostic (3.25e-2)" "prognostic unfavorable (1.85e-4)" "unprognostic (2.39e-2)" "unprognostic (1.72e-3)" "unprognostic (2.35e-2)" "unprognostic (7.40e-2)" "unprognostic (1.57e-2)" "unprognostic (2.54e-2)" "prognostic unfavorable (3.22e-15)" "unprognostic (2.75e-2)" "unprognostic (1.27e-1)" "unprognostic (3.93e-2)" "unprognostic (1.96e-2)" 214.1 101.9 46.2 106.5 50.4 3.7 107.1 51.1 291.0 137.7 66.7 95.2 23.2 160.7 27.6 41.7 119.4 72.1 159.3 46.1 50.5 116.9 52.5 199.3 21.1 59.9 47.3 157.4 40.1 18.1 50.8 251.3 58.3 66.1 36.7 2.0 40.7 53.2 22.2 47.6 51.3 207.3 51.6 53.9 76.9 27.7 54.0 21.6 91.2 33.2 18.2 156.8 85.9 60.1 57.7 192.9 349.5 722.0 528.8 484.2 162.2 514.3 349.6 380.4 483.5 1018.3 294.1 0.4 470.2 1215.2 3.1 337.2 242.2 163.2 182.5 27.5 47.0 42.7 174.0 216.5 1029.5 0.9 7.2 580.9 165.2 365.0 121.3 475.5 530.8 22.1 90.5 16.1 182.5 457.6 1.2 74.8 315.6 215.8 50.7 29.3 200.3 48.8 95.6 107.8 9.1 119.1 326.9 59.7 102.0 539.6 144.4 72.7 284.6 388.6 324.6 270.6 128.3 23.1 25.5 6.1 168.0 0.2 535.6 4.1 1.1 0.1 6.0 1.1 5.2 0.9 3.9 4.0 4.4 0.7 4.0 3.3 0.2 5.9 0.1 3.7 3.5 2.1 46.2 50.4 51.1 291.0 46.1 50.5 59.9 47.3 58.3 51.6 54.0 60.1 142.3 38.5 32.0 4.9 2.9 81.8 473.6 56.5 74.0 5.3 28.3 39.5 36.6 14.3 21.0 25.8 58.4 217.0 3.2 33.0 0.0 64.5 2.9 21.8 273.3 194.9 61.1 11.4 0.4 11.9 342.1 287.6 15.3 33.0 9.5 144.1 124.9 9.9 94.2 6.7 0.2 55.7 22.4 5.7 110.0 6.0 164.4 43.6 44.4 18.7 9.8 14.3 8.2 1.0 0.5 22.5 24.3 120.7 6.5 139.8 12.4 22.8 11.9 1.2 92.1 31.4 295.1 29.3 23.0 14.1 44.5 165.8 68.8 79.8 62.8 73.4 SERTAD3 RBT1 ENSG00000167565 "SERTA domain containing 3" Q9UJW9 19 40440844-40444335 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 187.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068262 Approved Nucleoli NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoli "HPA068262: AB_2685965" "unprognostic (1.56e-2)" "unprognostic (3.57e-2)" "unprognostic (1.10e-1)" "unprognostic (6.55e-3)" "unprognostic (6.50e-2)" "unprognostic (6.74e-2)" "unprognostic (2.24e-2)" "unprognostic (3.51e-3)" "unprognostic (7.18e-2)" "unprognostic (1.25e-1)" "unprognostic (1.28e-3)" "unprognostic (2.80e-2)" "unprognostic (8.74e-3)" "unprognostic (2.34e-1)" "unprognostic (2.88e-1)" "unprognostic (1.18e-1)" "unprognostic (4.66e-3)" 31.9 21.5 10.9 18.7 12.5 22.7 23.3 12.1 11.8 19.9 12.3 29.8 21.5 22.5 26.6 25.9 24.8 25.5 27.9 10.7 12.3 21.2 17.3 24.0 21.8 14.1 12.6 25.8 14.9 22.4 17.7 31.4 13.0 29.1 22.9 2.5 18.0 27.0 27.5 19.4 19.8 27.4 12.4 24.8 24.4 16.1 12.3 16.0 24.8 37.1 16.2 26.1 24.5 14.2 36.6 65.3 22.4 30.4 25.7 38.4 32.6 28.3 38.8 39.7 34.3 24.9 27.2 16.6 12.6 37.9 23.9 12.6 23.0 28.3 21.7 19.2 10.7 11.4 21.5 21.3 31.4 3.2 34.7 35.7 37.3 24.6 17.9 31.7 33.3 8.0 34.6 11.9 32.0 55.4 7.1 14.2 12.7 30.8 17.5 10.1 15.1 14.6 31.4 27.6 3.6 15.1 25.6 42.1 22.9 33.7 37.3 30.6 28.7 34.2 27.7 27.4 23.2 19.0 10.5 14.7 27.5 12.7 15.6 44.8 59.0 66.1 18.5 59.2 19.0 39.9 20.4 20.5 64.7 36.6 14.8 17.7 80.3 22.5 51.7 69.8 17.6 40.0 10.9 12.5 12.1 11.8 10.7 12.3 14.1 12.6 13.0 12.4 12.3 14.2 78.4 9.6 12.0 2.9 42.0 46.1 55.8 139.9 91.6 4.6 81.5 50.9 10.5 11.5 45.4 23.9 4.2 89.8 44.2 40.7 31.3 32.1 11.4 26.0 24.8 42.1 49.1 3.0 0.3 30.5 105.4 38.9 27.5 30.7 21.0 13.2 33.9 6.6 35.0 3.3 0.5 50.8 42.7 27.0 55.3 6.9 28.6 32.1 33.8 8.4 29.1 19.3 4.1 1.5 3.7 37.1 48.5 30.5 16.3 50.5 47.8 22.7 28.0 0.8 59.2 20.2 50.4 15.7 20.0 64.2 43.0 187.4 33.6 17.6 30.6 49.8 SESTD1 "DKFZp434O0515, Solo" ENSG00000187231 "SEC14 and spectrin domain containing 1" Q86VW0 2 179101678-179264832 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 175.5;Horizontal cells: 301.2;Oligodendrocytes: 311.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 45.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058236, HPA077408" Approved Enhanced "Intermediate filaments" NA Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" "Intermediate filaments" "HPA058236: AB_2732619, HPA077408: AB_2732344" "unprognostic (2.76e-1)" "unprognostic (3.55e-2)" "unprognostic (2.77e-1)" "unprognostic (2.12e-1)" "unprognostic (1.78e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.88e-4)" "unprognostic (9.47e-2)" "unprognostic (1.64e-1)" "unprognostic (2.59e-1)" "unprognostic (7.91e-3)" "unprognostic (9.21e-2)" "prognostic favorable (2.78e-11)" "prognostic unfavorable (2.67e-4)" "unprognostic (3.25e-2)" "unprognostic (1.25e-1)" "unprognostic (2.57e-2)" 15.4 2.4 11.6 3.2 17.2 4.7 11.2 12.5 11.4 6.2 0.9 7.1 2.0 5.8 3.9 4.5 4.5 6.4 6.3 8.2 10.3 6.7 3.4 9.2 3.4 16.2 13.5 4.5 3.3 3.9 3.6 6.8 14.6 4.2 3.8 7.5 11.0 4.6 3.6 4.5 5.4 8.1 15.1 3.5 5.5 9.0 18.1 2.9 3.7 5.8 4.9 10.0 4.8 23.6 0.0 2.1 25.5 4.6 45.2 19.5 13.5 9.0 3.7 3.7 6.3 4.6 6.0 4.5 11.7 8.7 4.5 4.2 11.0 5.1 6.8 3.3 2.9 5.5 11.2 12.3 3.5 3.1 2.3 14.6 2.1 5.7 14.3 8.9 15.2 4.6 0.8 2.3 6.4 3.1 7.2 0.3 6.6 4.7 2.6 10.3 16.8 2.9 10.0 23.2 5.6 9.5 8.0 3.4 2.5 18.7 0.5 3.4 26.7 12.3 6.2 6.3 4.7 1.3 0.0 11.0 6.2 1.2 3.7 0.0 0.9 0.0 0.0 0.7 0.0 1.2 0.0 0.0 0.4 1.5 0.0 0.0 0.1 0.3 1.6 0.0 0.0 0.2 11.6 17.2 12.5 11.4 8.2 10.3 16.2 13.5 14.6 15.1 18.1 23.6 46.2 109.0 29.9 53.2 30.6 9.8 24.7 19.1 7.4 31.3 30.4 15.6 15.3 28.6 32.9 12.9 18.8 10.7 5.7 11.9 17.6 31.3 9.8 61.3 33.1 32.1 25.0 7.2 110.8 27.7 73.4 65.1 13.7 175.5 0.0 23.1 21.4 9.6 12.3 301.2 147.9 7.3 14.2 28.7 43.4 7.3 12.2 37.2 14.2 89.0 21.9 33.4 5.2 86.5 311.1 33.3 13.3 30.5 4.7 67.7 22.5 39.1 42.8 10.4 19.7 43.7 29.2 34.9 66.0 10.2 10.1 18.1 5.7 9.8 9.7 119.9 SFN YWHAS ENSG00000175793 Stratifin P31947 1 26863149-26864456 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 2461.5;skin 1: 1219.1;vagina: 692.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 7750.0;Basal prostatic cells: 2119.7;Squamous epithelial cells: 3587.1;Suprabasal keratinocytes: 10714.0;Urothelial cells: 2780.0" "Cancer enhanced" "Detected in all" "cervical cancer: 1510.8;head and neck cancer: 2526.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 17 "basophil: 5.9" "Lineage enriched" "Detected in single" 17 "granulocytes: 5.9" "Cell line enhanced" "Detected in many" "A-431: 770.8;HaCaT: 1181.6;HBEC3-KT: 1819.0;hTCEpi: 1196.7" "Low region specificity" "Detected in many" "CAB006268, HPA011105, CAB040552" Enhanced Supported Cytosol "Secreted in other tissues" NA Yes 29000000 "Cluster 34: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" Cytosol "CAB006268: AB_425459, CAB040552: , HPA011105: AB_1844339" "unprognostic (5.70e-2)" "unprognostic (1.26e-1)" "unprognostic (8.37e-2)" "prognostic favorable (1.92e-4)" "unprognostic (1.26e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (5.68e-5)" "unprognostic (1.71e-2)" "unprognostic (2.99e-1)" "unprognostic (3.96e-1)" "prognostic unfavorable (6.01e-4)" "unprognostic (3.83e-1)" "prognostic unfavorable (7.45e-6)" "unprognostic (7.90e-3)" "unprognostic (3.25e-1)" "unprognostic (8.12e-2)" "unprognostic (2.06e-2)" 3.1 0.8 1.9 11.6 1.8 2.0 29.1 1.8 9.5 350.2 0.4 95.4 48.8 8.0 0.7 2461.5 2.2 21.4 1.3 1.9 1.6 16.0 3.7 56.1 0.2 9.0 4.4 0.9 2.2 0.1 2.7 1.6 4.3 77.2 32.5 0.6 332.8 3.2 5.0 1219.1 40.8 3.3 1.2 0.9 66.6 0.7 5.2 22.1 2.0 0.1 147.9 167.6 692.0 2.3 770.8 126.9 0.1 1.1 0.3 0.1 37.2 0.5 0.0 0.1 0.3 46.6 393.6 6.7 32.2 0.2 0.6 1181.6 0.3 1819.0 0.0 183.4 5.4 0.9 119.6 138.4 0.1 0.4 1.4 0.4 1196.7 0.6 310.1 0.2 0.2 0.7 1.8 4.5 0.1 163.8 0.7 0.3 2.3 132.6 208.7 0.5 0.4 43.1 281.3 173.9 0.7 0.7 181.2 31.9 1.8 2.9 83.6 1.5 0.5 0.5 337.2 0.3 4.9 1.0 5.8 3.8 1.5 0.7 0.7 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.9 1.8 1.8 9.5 1.9 1.6 9.0 4.4 4.3 1.2 5.2 2.3 1.6 179.5 162.2 0.0 5.0 7750.0 2119.7 1374.7 1714.2 0.0 72.6 119.9 0.8 24.3 285.6 16.5 0.0 18.6 0.7 972.0 3.9 48.8 0.0 138.0 20.1 45.3 67.4 0.0 0.0 76.2 59.9 46.2 221.2 251.8 32.3 0.0 0.4 4.5 1.9 0.0 0.1 140.7 114.0 0.6 479.7 0.0 0.0 9.7 533.6 0.0 1.0 0.0 0.0 0.0 0.1 524.8 933.0 0.0 21.2 1030.2 318.5 0.6 158.2 0.0 0.0 0.7 55.2 0.0 0.6 3587.1 10714.0 6.0 23.4 0.1 292.4 2780.0 SGO1 "NY-BR-85, SGOL1" ENSG00000129810 "Shugoshin 1" Q5FBB7 3 20160593-20186206 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.7;lymphoid tissue: 13.0;testis: 6.7" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 16.5;Extravillous trophoblasts: 42.6;Granulosa cells: 20.3;Hofbauer cells: 10.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 5 "basophil: 10.0;memory B-cell: 8.8;naive B-cell: 8.9;plasmacytoid DC: 4.1;T-reg: 2.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035501, HPA069302, HPA069857" Enhanced Enhanced Nucleoplasm,Kinetochore,Cytosol Yes Yes "Cluster 37: B-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Kinetochore, Cytosol" "HPA035501: AB_2732469, HPA069302: , HPA069857: AB_2686214" "unprognostic (6.87e-3)" "unprognostic (5.01e-2)" "unprognostic (2.25e-2)" "unprognostic (8.93e-3)" "unprognostic (2.51e-2)" "unprognostic (4.10e-2)" "unprognostic (2.55e-6)" "unprognostic (9.49e-3)" "unprognostic (2.45e-2)" "unprognostic (3.69e-2)" "unprognostic (1.65e-4)" "unprognostic (1.52e-2)" "unprognostic (0.00e+0)" "unprognostic (2.29e-2)" "unprognostic (4.95e-2)" "unprognostic (4.14e-1)" "unprognostic (1.64e-1)" 0.3 0.1 0.3 3.3 0.7 8.7 0.5 0.9 0.5 0.4 0.0 2.1 2.3 0.4 0.0 1.9 0.1 0.4 0.1 0.3 0.4 0.3 0.6 0.3 6.2 0.8 0.6 0.2 0.1 0.2 0.0 1.7 0.6 0.2 2.8 0.1 0.4 0.1 0.1 1.1 2.5 1.0 0.3 1.4 1.5 6.7 0.6 13.0 0.2 0.0 6.6 0.9 0.7 1.2 20.3 23.9 29.9 18.5 1.4 2.6 20.2 21.3 10.1 31.2 33.6 16.5 24.0 30.7 10.6 8.6 21.2 11.4 28.7 11.3 37.6 40.9 19.6 34.6 15.6 12.8 0.2 32.0 28.8 0.3 0.9 33.3 13.1 4.0 18.5 34.9 31.3 52.2 24.6 19.4 52.4 15.4 30.0 20.3 17.0 31.8 38.4 17.7 7.5 14.9 14.2 15.4 23.6 27.2 13.1 22.7 18.2 21.3 4.7 22.5 27.3 20.5 43.3 22.8 57.4 35.2 12.5 31.1 35.0 10.0 0.1 1.4 0.2 0.2 0.1 8.8 0.6 0.7 0.3 8.9 0.2 0.3 1.4 0.3 0.2 4.1 2.6 0.6 0.3 0.7 0.9 0.5 0.3 0.4 0.8 0.6 0.6 0.3 0.6 1.2 0.1 0.0 0.5 0.0 1.9 0.0 0.0 0.0 0.0 0.0 2.0 3.4 0.0 0.0 0.0 1.8 0.0 16.5 1.5 0.0 0.0 1.1 0.0 2.3 1.6 1.2 0.0 0.0 0.0 1.8 42.6 3.3 0.0 2.9 1.3 20.3 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 2.6 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 4.9 1.0 4.3 0.0 0.0 SGO2 "FLJ25211, SGOL2, TRIPIN" ENSG00000163535 "Shugoshin 2" Q562F6 2 200510008-200584096 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.9;testis: 32.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 11.6;Endometrial ciliated cells: 12.1;Extravillous trophoblasts: 31.0;granulocytes: 11.4;Granulosa cells: 23.4;Hofbauer cells: 13.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "basophil: 16.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 16.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035163, HPA040817" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 34: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA035163: AB_10602397, HPA040817: AB_2677149" "unprognostic (3.43e-1)" "unprognostic (1.70e-1)" "unprognostic (7.06e-3)" "unprognostic (6.71e-3)" "unprognostic (1.90e-1)" "unprognostic (1.77e-1)" "unprognostic (7.55e-6)" "unprognostic (1.12e-2)" "unprognostic (1.98e-3)" "unprognostic (4.87e-2)" "unprognostic (1.37e-4)" "unprognostic (9.49e-2)" "unprognostic (8.07e-9)" "unprognostic (5.21e-2)" "unprognostic (5.43e-2)" "unprognostic (9.86e-2)" "unprognostic (2.02e-1)" 3.3 0.9 0.6 4.4 0.9 6.8 1.9 0.8 0.9 0.9 0.3 3.1 2.5 1.8 0.7 2.4 1.4 1.2 1.0 0.5 0.9 0.9 0.8 1.5 7.9 0.9 0.9 1.9 0.5 1.1 0.3 2.6 0.9 1.4 3.2 0.9 0.7 0.7 0.4 2.3 2.6 2.0 0.7 2.0 1.8 32.6 0.9 14.9 1.2 0.6 8.1 1.5 0.9 1.2 34.6 16.2 37.0 17.4 5.2 7.9 23.7 38.7 16.6 32.0 33.1 24.3 23.5 22.5 18.6 18.1 34.4 25.3 33.6 20.1 54.5 48.0 16.9 43.5 21.6 17.5 1.6 43.9 33.1 3.4 2.5 32.9 17.3 8.0 29.4 31.3 33.1 31.6 61.4 15.4 35.9 17.9 26.7 24.9 41.2 28.8 49.1 21.3 13.3 13.6 22.2 15.4 28.6 13.3 16.3 29.2 14.1 25.2 18.1 33.9 34.0 31.6 34.0 14.3 33.5 49.8 21.4 28.9 49.4 16.7 1.4 4.5 2.2 1.4 1.4 2.7 2.4 2.2 0.8 3.2 1.8 2.2 1.0 2.0 1.7 1.7 3.6 1.2 0.6 0.9 0.8 0.9 0.5 0.9 0.9 0.9 0.9 0.7 0.9 1.2 9.4 3.2 3.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 5.8 7.1 0.0 0.0 6.2 0.0 0.0 11.6 7.8 0.0 3.9 3.9 0.0 12.1 5.3 3.3 0.0 0.0 0.0 2.7 31.0 6.7 0.0 3.6 11.4 23.4 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 1.6 0.0 0.0 0.0 0.0 3.2 0.0 0.0 1.7 0.0 0.0 2.5 8.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 3.4 3.8 4.0 0.0 0.0 SH3RF2 "FLJ23654, Hepp1, POSHER, PPP1R39, RNF158" ENSG00000156463 "SH3 domain containing ring finger 2" Q8TEC5 5 145936578-146081791 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Protein phosphatase inhibitor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 58.1;skeletal muscle: 42.4;skin 1: 56.8" "Cell type enriched" "Detected in many" 5 "Late spermatids: 7869.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "basal ganglia: 6.1;cerebral cortex: 4.1;thalamus: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 70.3;GAMG: 29.8;hTERT-RPE1: 33.5" "Region enriched" "Detected in many" 14 "basal ganglia: 26.7" "Region enhanced" "Detected in many" "basal ganglia: 9.7" "HPA035903, HPA058119" Uncertain Enhanced Nucleoplasm NA Yes "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 39: CACO-2 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA035903: AB_10696515, HPA058119: AB_2683611" "unprognostic (8.90e-3)" "unprognostic (2.00e-3)" "unprognostic (5.11e-3)" "unprognostic (1.66e-2)" "unprognostic (1.45e-3)" "unprognostic (1.47e-2)" "unprognostic (9.96e-3)" "unprognostic (8.22e-2)" "unprognostic (3.92e-1)" "unprognostic (7.37e-3)" "unprognostic (2.44e-3)" "unprognostic (1.66e-1)" "unprognostic (2.98e-2)" "unprognostic (5.21e-2)" "unprognostic (1.46e-1)" "unprognostic (2.64e-2)" "unprognostic (4.13e-3)" 1.9 0.9 0.6 2.5 6.1 0.0 4.7 0.0 4.1 7.6 0.2 14.3 16.0 1.1 3.6 34.1 6.1 11.9 58.1 0.9 0.5 0.9 7.0 2.7 0.2 0.0 0.3 0.4 15.4 0.0 1.6 0.1 0.0 2.7 14.3 0.5 12.1 0.6 42.4 56.8 13.7 1.1 0.0 0.0 20.5 6.8 1.7 1.0 6.3 8.8 7.7 1.2 20.6 0.4 21.0 5.7 0.2 1.1 0.0 0.0 0.0 0.2 1.7 4.1 1.7 70.3 19.0 0.0 10.5 0.9 29.8 18.9 0.0 22.4 4.0 0.3 0.3 0.0 8.5 9.5 1.2 0.0 0.0 0.2 11.9 6.4 14.8 33.5 0.2 0.5 0.0 0.0 1.8 0.1 0.0 0.0 1.6 17.3 1.5 0.0 0.2 0.0 8.7 2.0 0.0 0.0 1.2 0.4 0.5 1.0 6.6 0.1 9.8 0.8 17.3 1.5 6.7 0.0 0.0 0.0 10.6 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.6 6.1 0.0 4.1 0.9 0.5 0.0 0.3 0.0 0.0 1.7 0.4 4.1 16.0 2.3 1.6 0.0 55.1 5.4 14.5 38.7 0.4 3.9 3.3 510.0 8.6 6.7 1.8 0.0 0.2 0.2 38.9 0.0 5.7 1511.3 11.9 0.9 9.7 1.2 0.0 10.5 8.7 0.0 15.4 50.4 26.7 1.3 0.1 0.7 8.4 0.2 0.0 2.2 16.1 8.2 0.0 4.9 7869.1 25.7 2.6 8.8 10.3 0.6 1.6 0.0 1.5 0.7 21.4 22.9 34.6 0.6 2.2 26.6 0.9 4.4 0.1 13.1 1.6 6.3 31.4 20.7 70.9 50.0 0.0 0.7 2.9 33.2 6.6 SHCBP1 "FLJ22009, PAL" ENSG00000171241 "SHC binding and spindle associated 1" Q8NEM2 16 46578591-46621379 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.4;lymphoid tissue: 10.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 36.2;Extravillous trophoblasts: 28.7;Plasma cells: 38.3;Spermatocytes: 33.7;Spermatogonia: 23.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA048876 Uncertain Approved "Nuclear bodies,Microtubules,Midbody,Mitotic spindle" Yes Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies" "Microtubules, Midbody, Mitotic spindle" "HPA048876: AB_2680542" "unprognostic (2.44e-3)" "unprognostic (1.13e-1)" "unprognostic (2.98e-2)" "unprognostic (2.74e-1)" "unprognostic (2.54e-2)" "unprognostic (2.35e-2)" "unprognostic (2.96e-4)" "unprognostic (2.26e-3)" "unprognostic (5.35e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (4.47e-5)" "unprognostic (4.81e-2)" "unprognostic (2.22e-16)" "unprognostic (3.59e-2)" "unprognostic (3.86e-2)" "unprognostic (2.66e-1)" "unprognostic (2.66e-1)" 0.7 0.5 0.5 5.1 0.5 17.4 0.9 1.2 0.6 0.6 0.4 1.9 1.2 0.6 0.6 3.5 0.2 0.6 1.0 0.4 0.2 5.4 0.2 1.0 9.8 0.4 0.3 0.3 0.2 0.2 0.2 2.4 0.4 0.3 2.2 0.2 0.8 0.2 1.5 3.3 1.5 1.7 0.1 4.4 0.9 5.2 0.5 8.8 0.3 0.2 10.6 1.2 1.2 0.7 33.8 30.8 11.9 15.3 3.1 6.2 16.2 60.7 24.6 59.2 26.8 14.6 20.8 28.0 30.2 28.8 26.8 21.0 29.3 21.7 73.8 17.7 17.2 28.2 25.8 30.3 0.1 28.5 35.4 1.2 1.6 45.9 18.1 5.9 33.0 14.9 12.7 28.3 69.7 21.5 24.0 23.7 10.0 17.2 31.6 45.4 89.9 44.8 13.7 9.4 5.0 7.2 46.0 23.7 11.1 11.4 13.0 23.4 16.1 43.9 28.7 43.5 54.0 24.9 36.7 46.7 21.4 31.3 45.8 0.2 0.3 0.6 0.2 0.5 0.0 1.7 0.3 0.1 0.3 1.2 0.0 0.1 0.4 0.1 2.4 0.7 1.2 1.1 0.5 0.5 1.2 0.6 0.4 0.2 0.4 0.3 0.4 0.1 0.5 0.7 0.2 0.0 1.1 1.3 7.1 1.7 0.7 1.2 0.0 0.3 0.6 1.1 1.9 1.5 1.4 0.0 0.0 11.3 0.8 1.9 0.0 0.2 8.4 0.7 1.7 1.7 0.0 36.2 2.1 0.0 28.7 3.7 4.1 1.5 0.0 7.6 1.8 0.3 12.6 0.0 0.7 2.2 2.0 4.5 3.3 2.3 0.6 4.0 1.8 2.8 2.8 0.8 0.0 1.0 0.5 0.1 0.1 0.4 38.3 0.5 0.4 0.1 0.1 0.3 0.0 0.5 6.3 33.7 23.7 3.6 0.6 3.7 2.2 0.8 3.4 1.1 SHISA3 hShisa3 ENSG00000178343 "Shisa family member 3" A0PJX4 4 42397488-42402487 "Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.3;heart muscle: 15.5;kidney: 21.4" "Group enriched" "Detected in some" 7 "Distal tubular cells: 43.0;Fibroblasts: 19.4;Hepatic stellate cells: 55.0" "Cancer enhanced" "Detected in many" "lung cancer: 7.6;renal cancer: 7.8" "Group enriched" "Detected in all" 4 "midbrain: 13.3;thalamus: 10.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "AN3-CA: 219.6;PC-3: 130.4" "Region enriched" "Detected in many" 23 "olfactory bulb: 51.7" "Region enriched" "Detected in many" 8 "spinal cord: 21.4" HPA054754 Approved "Lipid droplets,Cytosol" NA Yes "Cluster 24: B-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 43: Cardiomyocytes - Nuclear processes" Cytosol "Lipid droplets" "HPA054754: AB_2682593" "unprognostic (9.04e-3)" "unprognostic (3.47e-3)" "unprognostic (1.37e-1)" "unprognostic (1.80e-2)" "unprognostic (1.26e-1)" "unprognostic (6.78e-3)" "unprognostic (1.26e-2)" "unprognostic (2.86e-1)" "unprognostic (3.04e-1)" "unprognostic (1.37e-3)" "unprognostic (3.42e-2)" "unprognostic (1.95e-1)" "unprognostic (5.99e-2)" "unprognostic (5.32e-2)" "unprognostic (3.10e-2)" "unprognostic (1.64e-1)" "unprognostic (4.99e-3)" 4.1 1.8 1.8 1.8 1.6 0.0 2.3 1.1 1.6 0.7 1.2 6.2 2.2 0.2 0.3 1.7 0.5 1.0 15.5 1.0 2.2 21.4 0.6 5.7 7.0 1.7 13.3 0.3 0.2 0.2 0.6 0.0 2.6 0.8 3.0 0.1 0.6 1.0 1.6 0.5 10.4 4.3 1.4 0.4 2.9 0.6 10.1 0.1 5.0 1.4 0.8 3.5 1.3 1.2 0.0 0.0 0.0 219.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 23.7 0.1 0.0 0.0 23.3 0.0 0.0 0.0 2.6 0.0 0.1 0.0 6.6 0.0 0.8 0.4 0.0 0.0 0.0 0.0 5.2 0.3 0.0 0.0 0.0 0.0 1.2 0.0 10.1 0.0 130.4 0.2 0.0 0.0 9.0 0.0 0.1 0.3 0.0 0.0 0.0 8.1 0.1 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.6 1.1 1.6 1.0 2.2 1.7 13.3 2.6 1.4 10.1 1.2 4.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 2.2 0.0 0.0 3.7 0.0 0.0 0.1 0.1 43.0 0.0 0.0 0.1 2.5 3.7 0.0 5.3 0.0 0.0 0.0 19.4 0.5 0.1 0.0 1.1 55.0 0.2 0.1 0.0 0.1 0.1 0.0 0.6 0.3 0.0 3.4 0.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.3 0.0 0.0 2.4 0.0 0.1 0.0 0.2 1.4 0.5 0.4 0.1 0.0 0.0 0.0 2.4 0.1 0.0 SKA1 "C18orf24, MGC10200" ENSG00000154839 "Spindle and kinetochore associated complex subunit 1" Q96BD8 18 50375040-50394168 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 12.0;lymphoid tissue: 4.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 22.3;Extravillous trophoblasts: 9.2;Plasma cells: 10.0;Spermatocytes: 16.7;Spermatogonia: 13.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "Karpas-707: 82.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA045495 Approved Approved Microtubules NA Yes "Cluster 17: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules "HPA045495: AB_10960405" "unprognostic (2.18e-2)" "unprognostic (7.85e-3)" "unprognostic (7.66e-3)" "unprognostic (5.93e-3)" "unprognostic (1.91e-1)" "unprognostic (1.25e-1)" "prognostic unfavorable (9.60e-8)" "unprognostic (1.03e-3)" "unprognostic (1.16e-2)" "unprognostic (1.20e-2)" "unprognostic (1.18e-4)" "unprognostic (3.91e-3)" "unprognostic (0.00e+0)" "unprognostic (4.50e-3)" "unprognostic (4.66e-2)" "unprognostic (2.22e-2)" "unprognostic (1.79e-1)" 0.4 0.5 0.9 2.2 0.8 12.0 0.3 2.5 1.1 0.4 0.8 1.6 1.7 0.6 0.2 2.5 0.2 0.3 0.2 1.0 0.5 0.1 0.3 0.4 4.9 1.0 0.9 0.2 0.4 0.1 0.0 1.6 1.2 0.3 2.1 0.4 0.3 0.1 0.6 1.5 1.4 1.1 0.3 1.3 0.8 4.3 1.3 3.6 0.3 0.2 4.8 0.5 0.7 2.4 27.1 10.8 18.6 19.0 1.2 2.1 9.9 30.7 10.6 29.9 28.5 4.7 10.6 21.1 7.6 11.0 25.8 23.6 25.6 13.0 31.4 34.6 2.6 27.0 5.5 18.3 2.3 42.2 26.8 1.5 1.3 20.7 8.2 3.2 20.0 20.0 30.8 82.6 26.4 5.7 34.6 12.1 14.2 6.5 6.4 17.3 18.3 23.5 8.5 1.6 13.7 10.9 17.2 9.9 13.6 15.3 11.4 20.2 10.1 32.8 19.0 12.8 31.8 27.5 41.6 32.4 18.2 34.9 33.3 0.9 0.4 0.1 0.1 0.1 0.1 0.2 0.1 0.5 0.2 0.3 0.2 0.1 0.6 0.6 0.2 0.2 0.4 0.2 0.9 0.8 2.5 1.1 1.0 0.5 1.0 0.9 1.2 0.3 1.3 2.4 0.2 0.0 2.2 0.0 2.8 1.0 0.2 0.4 0.0 0.4 0.7 0.6 0.4 0.0 0.8 0.0 2.1 4.4 0.7 1.6 0.0 0.1 4.5 0.5 0.7 0.4 1.2 22.3 0.2 0.0 9.2 1.4 0.5 1.1 0.0 4.9 2.2 0.1 5.3 0.0 0.1 2.7 0.0 0.8 0.9 2.2 0.3 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 1.1 0.0 10.0 0.4 0.1 0.1 0.2 0.8 0.0 0.2 1.4 16.7 13.5 3.7 0.3 1.5 1.4 0.5 3.4 1.0 SKA3 "C13orf3, MGC4832, RAMA1" ENSG00000165480 "Spindle and kinetochore associated complex subunit 3" Q8IX90 13 21153595-21176552 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.7;lymphoid tissue: 12.1;testis: 6.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 12.8;Extravillous trophoblasts: 21.0;Spermatocytes: 21.7;Spermatogonia: 18.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039272, HPA039356, HPA061534" Approved Supported "Mitotic spindle,Centrosome,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Mitotic spindle" "Centrosome, Cytosol" "HPA039272: AB_10805359, HPA039356: AB_10805475, HPA061534: " "unprognostic (3.46e-2)" "unprognostic (7.21e-2)" "unprognostic (2.15e-1)" "unprognostic (1.62e-2)" "unprognostic (2.04e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (9.73e-6)" "unprognostic (2.03e-3)" "prognostic unfavorable (8.71e-4)" "unprognostic (2.03e-1)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.39e-2)" "unprognostic (0.00e+0)" "unprognostic (2.24e-3)" "unprognostic (1.81e-1)" "unprognostic (1.22e-1)" "unprognostic (1.32e-1)" 0.2 0.1 0.2 2.5 0.2 4.7 0.8 0.1 0.3 0.2 0.0 1.7 1.0 0.5 0.0 1.9 0.2 0.4 0.0 0.5 0.2 0.1 0.2 0.2 4.3 0.2 0.2 0.0 0.0 0.0 0.0 1.6 0.2 0.0 3.0 0.0 0.2 0.0 0.0 1.8 2.1 1.1 0.2 0.7 1.0 6.3 0.3 12.1 0.1 0.1 3.7 0.4 0.5 0.2 26.1 13.0 25.8 20.5 0.9 5.1 19.1 35.0 14.8 42.1 28.7 23.4 27.8 35.6 10.0 19.3 18.5 24.4 34.4 15.2 54.7 30.3 15.9 47.3 7.7 12.7 0.0 39.5 17.7 1.5 1.0 34.9 15.4 4.2 20.7 30.6 26.3 14.2 33.9 21.0 60.7 37.8 27.9 42.8 23.8 36.5 50.3 15.8 12.2 9.9 30.1 11.1 11.8 17.1 8.1 17.9 15.3 33.5 8.7 16.0 23.8 17.0 43.9 9.0 19.7 34.5 4.4 31.1 51.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.5 0.1 0.2 0.2 0.1 0.3 0.5 0.2 0.2 0.2 0.2 0.2 0.3 0.2 0.4 0.0 0.0 0.0 2.6 2.0 0.7 2.4 0.0 0.1 0.9 0.8 0.8 0.0 1.8 0.0 0.0 8.7 1.0 2.1 0.0 1.2 6.3 2.8 0.9 1.4 0.0 12.8 0.8 1.3 21.0 2.1 1.5 1.6 0.0 5.8 1.8 0.4 5.5 0.0 0.6 1.8 2.0 1.9 2.9 7.7 1.5 1.6 0.0 1.9 0.8 0.3 3.1 0.0 0.2 1.0 1.6 1.2 8.5 0.3 0.4 0.6 2.0 0.4 0.0 0.3 2.3 21.7 18.2 5.8 2.8 2.2 1.2 0.5 5.0 0.7 SKP2 "FBL1, FBXL1, p45" ENSG00000145604 "S-phase kinase associated protein 2" Q13309 5 36151989-36196849 "Cancer-related genes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 37.9" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 134.4;Extravillous trophoblasts: 227.3;Syncytiotrophoblasts: 83.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 274.7;RH-30: 286.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013491, CAB013533, HPA051196, HPA054633" Approved Supported Nucleoplasm,Cytosol NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Cytosol" "CAB013491: AB_2533074, CAB013533: , HPA051196: AB_2681383, HPA054633: AB_2682550" "unprognostic (2.32e-2)" "unprognostic (2.87e-1)" "unprognostic (1.26e-1)" "unprognostic (5.74e-2)" "unprognostic (9.56e-2)" "unprognostic (1.52e-2)" "unprognostic (1.21e-3)" "unprognostic (2.22e-1)" "prognostic unfavorable (3.72e-7)" "prognostic favorable (8.57e-4)" "unprognostic (5.06e-2)" "unprognostic (2.71e-1)" "prognostic unfavorable (4.77e-15)" "unprognostic (2.50e-2)" "unprognostic (3.73e-1)" "unprognostic (1.63e-1)" "unprognostic (2.19e-1)" 4.9 4.0 3.6 5.8 3.9 11.4 4.9 4.7 4.5 5.9 3.9 6.1 6.3 4.7 4.3 8.3 5.1 2.9 2.5 3.9 3.1 2.3 9.8 4.2 7.9 3.7 3.5 5.2 3.8 2.5 4.0 37.9 3.9 4.0 6.1 4.6 4.0 3.7 2.2 5.7 6.5 4.1 3.9 5.9 4.0 2.6 3.7 12.3 3.1 1.6 8.3 4.7 5.6 5.4 25.4 14.8 35.6 54.3 15.5 20.1 274.7 31.2 25.7 89.5 48.7 83.3 22.8 43.3 10.6 20.0 13.3 28.3 53.3 46.7 71.0 19.2 46.7 23.9 51.4 47.1 6.1 44.8 11.4 18.1 12.2 16.9 8.5 7.7 24.2 40.2 37.9 9.1 31.9 16.4 58.9 26.8 51.5 23.8 24.2 53.7 286.7 28.3 7.2 28.1 45.5 46.8 94.3 27.4 14.1 32.2 22.7 33.3 8.0 31.4 36.1 13.5 24.5 12.4 13.1 50.8 15.2 61.3 21.9 9.2 6.6 13.4 4.2 6.1 6.9 5.2 4.7 4.5 14.0 6.0 6.4 4.6 1.1 6.2 3.2 3.5 4.8 4.7 3.6 3.9 4.7 4.5 3.9 3.1 3.7 3.5 3.9 3.9 3.7 5.4 4.4 22.4 8.9 11.8 8.7 3.7 2.4 7.1 12.0 8.2 3.6 4.2 1.3 1.5 1.7 1.8 10.4 134.4 7.4 2.4 1.9 2.4 0.7 5.2 6.5 6.5 3.0 14.1 22.4 2.9 227.3 11.6 7.1 2.4 2.5 20.9 1.8 11.9 35.0 0.0 13.1 6.0 4.1 9.3 3.1 0.3 4.1 5.3 1.8 12.2 7.6 2.5 9.2 11.6 29.5 2.6 3.4 6.4 10.9 1.0 3.2 1.4 6.2 6.8 0.0 11.5 4.1 1.4 6.4 19.8 4.0 83.9 5.6 11.8 9.6 1.2 SLBP HBP ENSG00000163950 "Stem-loop binding protein" Q14493 4 1692731-1712344 "Predicted intracellular proteins" "mRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 263.6;Spermatogonia: 294.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019254, HPA061670" Supported Supported Nucleoplasm,Nucleoli,Cytosol Yes Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli, Cytosol" "HPA019254: AB_1856951, HPA061670: AB_2684581" "unprognostic (1.81e-2)" "unprognostic (6.80e-3)" "unprognostic (2.05e-2)" "unprognostic (1.59e-1)" "unprognostic (1.94e-1)" "unprognostic (7.09e-3)" "prognostic unfavorable (2.29e-5)" "unprognostic (5.53e-2)" "unprognostic (1.94e-2)" "unprognostic (1.13e-2)" "unprognostic (9.81e-3)" "unprognostic (9.55e-3)" "unprognostic (4.58e-2)" "unprognostic (7.31e-2)" "unprognostic (1.95e-1)" "unprognostic (1.44e-1)" "unprognostic (7.07e-2)" 29.9 26.4 38.6 37.6 40.2 114.2 26.7 38.0 65.7 28.4 34.4 30.6 23.9 27.3 32.9 35.9 27.6 21.9 18.4 40.9 43.6 35.1 33.9 27.2 71.7 36.4 39.1 28.0 24.4 24.0 26.7 42.0 39.3 22.8 30.6 17.1 25.6 25.3 22.6 37.7 25.6 28.8 37.7 28.3 26.9 63.1 41.8 53.5 27.3 19.2 69.5 35.0 28.0 41.1 132.7 53.9 76.6 80.7 65.3 70.0 81.9 120.1 92.5 131.4 133.8 120.3 144.7 180.6 67.4 96.0 150.9 77.8 147.0 103.0 154.1 75.4 98.5 215.9 63.3 123.6 82.6 208.3 102.8 55.0 84.7 98.1 67.3 74.4 76.5 108.8 172.7 170.3 163.2 52.8 314.6 200.6 97.4 136.7 108.6 241.1 126.3 105.3 131.0 99.5 86.1 69.3 95.4 59.6 69.5 96.8 99.0 127.7 66.3 108.0 63.8 116.1 180.4 107.4 192.2 428.3 99.6 176.0 106.0 25.7 65.4 47.5 47.1 49.7 43.3 51.6 59.7 64.8 50.6 37.8 50.6 49.6 95.8 46.3 44.8 42.2 77.9 75.4 38.6 40.2 38.0 65.7 40.9 43.6 36.4 39.1 39.3 37.7 41.8 41.1 35.2 16.0 18.8 7.2 96.3 105.2 96.3 38.8 61.5 19.4 35.9 34.0 8.2 27.1 23.6 36.8 25.0 166.3 80.5 28.8 107.6 50.6 75.9 38.8 34.9 36.1 35.9 146.0 14.6 31.3 51.8 49.1 53.5 55.5 23.5 45.9 30.0 27.0 81.3 25.2 15.1 33.6 44.7 36.8 58.6 41.6 44.1 60.3 65.8 6.5 64.4 27.4 43.3 9.0 14.4 38.7 25.3 44.0 94.2 88.6 22.5 55.4 16.3 13.6 13.1 46.3 43.8 263.6 294.0 84.1 105.8 44.7 96.6 33.2 44.1 76.5 SLC29A2 "DER12, ENT2, HNP36" ENSG00000174669 "Solute carrier family 29 member 2" Q14542 11 66362521-66372214 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skeletal muscle: 90.8;tongue: 47.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 46.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 44.3;CAPAN-2: 53.5;T-47d: 55.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018168 Approved Uncertain Nucleoplasm NA Yes "Cluster 32: T-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 1: K-562 - Erythropoiesis" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA018168: AB_1857077" "unprognostic (3.20e-2)" "unprognostic (4.50e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (3.37e-1)" "unprognostic (5.08e-2)" "unprognostic (5.64e-2)" "unprognostic (1.60e-1)" "unprognostic (1.96e-1)" "unprognostic (2.09e-1)" "unprognostic (1.76e-1)" "unprognostic (5.28e-2)" "prognostic favorable (2.78e-4)" "unprognostic (2.55e-2)" "unprognostic (1.59e-1)" "unprognostic (1.13e-1)" "unprognostic (6.38e-3)" 6.7 0.9 4.2 2.5 4.3 0.8 7.4 9.8 5.6 1.9 4.2 5.7 7.8 0.9 3.1 3.3 3.6 1.4 11.9 4.1 4.0 6.9 1.5 4.4 2.8 7.4 6.9 0.7 8.7 12.9 6.1 4.1 8.2 5.2 4.1 3.1 7.2 2.4 90.8 2.8 7.4 0.3 4.1 2.1 9.4 0.5 5.9 2.3 5.4 47.3 1.9 1.2 2.6 3.7 14.2 11.4 8.2 1.8 1.2 0.3 44.3 0.6 0.0 0.4 0.6 20.2 53.5 6.1 10.4 0.1 3.1 12.9 11.4 9.7 0.0 0.5 18.6 11.7 12.4 1.5 1.3 21.9 0.4 0.7 4.3 1.5 4.1 5.2 0.5 5.1 33.0 0.0 0.0 34.5 1.6 31.9 21.8 35.1 8.1 1.3 0.3 26.4 22.2 10.4 16.1 6.6 1.0 18.4 1.2 2.4 55.2 4.1 0.0 0.3 11.2 0.4 0.0 0.3 0.8 0.5 0.9 0.5 0.7 0.0 0.0 0.0 1.3 0.0 0.4 0.2 0.7 1.7 0.3 0.7 1.7 1.7 0.1 0.0 0.0 0.6 0.1 0.5 4.2 4.3 9.8 5.6 4.1 4.0 7.4 6.9 8.2 4.1 5.9 3.7 0.6 3.2 6.3 9.4 2.2 0.6 4.7 5.4 1.2 2.5 7.6 5.8 12.3 4.3 6.5 14.7 12.5 46.4 0.7 6.0 3.9 5.0 0.1 2.1 0.5 0.9 2.4 2.1 11.2 6.7 16.5 1.7 11.2 5.4 4.5 1.8 0.4 0.9 4.4 5.0 10.8 9.2 4.1 0.8 0.4 0.0 0.0 0.5 0.0 2.8 0.9 2.3 0.0 7.5 0.8 3.5 4.7 0.4 1.5 4.7 1.6 0.5 3.8 3.7 0.0 4.4 2.1 0.4 0.5 3.5 0.0 13.5 2.1 0.4 10.6 3.4 SLC43A3 "DKFZp762A227, Eeg1, FOAP-13, PRO1659, SEEEG-1" ENSG00000134802 "Solute carrier family 43 member 3" Q8NBI5 11 57406954-57427580 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 146.9" "Cell type enhanced" "Detected in many" "Ductal cells: 75.5;granulocytes: 67.0;Hofbauer cells: 73.7;Langerhans cells: 74.6;Sertoli cells: 65.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 105.7;intermediate monocyte: 127.0;myeloid DC: 85.8;non-classical monocyte: 146.3;plasmacytoid DC: 85.7" "Group enriched" "Detected in all" 4 "dendritic cells: 85.8;monocytes: 146.3" "Cell line enhanced" "Detected in many" "HL-60: 513.8;HMC-1: 428.4;RPMI-8226: 570.9;WM-115: 532.1" "Region enhanced" "Detected in many" "olfactory bulb: 10.3" "Low region specificity" "Detected in all" "HPA030551, HPA077244" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Nucleoplasm, Plasma membrane" "HPA030551: AB_10604094, HPA077244: AB_2732335" "unprognostic (2.64e-1)" "unprognostic (7.63e-2)" "unprognostic (9.67e-3)" "unprognostic (7.41e-3)" "unprognostic (6.59e-3)" "unprognostic (5.30e-3)" "unprognostic (1.29e-1)" "unprognostic (4.91e-2)" "unprognostic (1.36e-1)" "unprognostic (2.26e-1)" "unprognostic (5.73e-2)" "unprognostic (3.97e-2)" "prognostic unfavorable (3.97e-13)" "unprognostic (8.16e-2)" "unprognostic (1.77e-1)" "unprognostic (8.34e-2)" "unprognostic (1.00e-1)" 61.4 16.8 5.2 34.8 5.9 58.0 50.3 5.9 7.3 40.2 6.8 23.7 8.3 28.1 4.5 34.8 30.0 28.5 34.8 5.5 7.1 15.9 146.9 46.9 26.5 6.7 6.4 24.3 13.7 3.9 4.9 14.3 7.3 14.4 11.8 0.9 35.2 7.5 15.6 34.6 20.6 25.5 6.3 20.8 20.1 4.7 11.1 23.2 76.3 13.3 28.9 30.7 28.2 8.5 289.2 0.0 16.0 0.4 52.9 76.9 0.7 22.0 93.0 31.6 54.1 0.0 61.4 165.0 9.8 52.0 16.3 161.8 47.0 28.8 63.3 1.0 0.2 257.3 93.0 0.0 106.6 513.8 428.4 231.7 0.9 306.5 3.5 22.9 89.7 75.0 299.8 154.4 123.7 0.6 108.6 328.2 24.3 0.0 5.3 221.8 3.3 570.9 76.1 0.0 38.0 0.0 62.2 1.4 263.5 1.5 24.1 77.3 48.1 1.5 81.4 209.2 62.5 0.3 0.9 41.3 187.3 183.2 532.1 15.2 105.7 23.4 19.6 127.0 22.2 9.6 13.5 26.8 85.8 7.1 10.4 10.5 9.0 3.9 146.3 85.7 26.5 60.7 5.2 5.9 5.9 7.3 5.5 7.1 6.7 6.4 7.3 6.3 11.1 8.5 19.8 16.0 49.1 1.6 6.1 46.8 7.4 30.8 48.3 0.5 8.0 14.2 3.7 28.6 26.1 1.8 0.0 0.6 11.9 0.3 0.0 75.5 1.0 1.0 3.1 33.0 0.0 38.3 0.1 6.4 5.0 33.4 2.0 3.0 67.0 2.9 14.3 61.7 73.7 0.0 0.2 0.6 16.2 21.0 74.6 1.7 9.9 47.0 30.2 8.4 10.2 0.6 3.1 8.5 0.8 9.4 0.5 12.4 22.5 14.5 0.0 0.1 4.9 0.1 65.7 15.5 22.0 0.7 1.1 13.6 17.6 0.8 11.8 12.3 1.2 3.0 SLC9A3R1 "EBP50, NHERF, NHERF1" ENSG00000109062 "SLC9A3 regulator 1" O14745 17 74748628-74769353 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Wnt signaling pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 352.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 295.8;Proximal enterocytes: 536.9;Proximal tubular cells: 433.0;Squamous epithelial cells: 303.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 572.4;SK-BR-3: 450.7;T-47d: 873.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001962, HPA009672, HPA027247" Enhanced Approved "Vesicles,Plasma membrane,Centriolar satellite" NA Yes 940000 "Cluster 2: Granulocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "Vesicles, Centriolar satellite" "CAB001962: , HPA009672: AB_1857215, HPA027247: AB_10601162" "unprognostic (1.29e-1)" "unprognostic (4.58e-2)" "unprognostic (1.73e-2)" "unprognostic (5.51e-2)" "unprognostic (5.83e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (9.83e-5)" "unprognostic (7.41e-2)" "unprognostic (5.61e-2)" "unprognostic (5.38e-2)" "unprognostic (7.53e-2)" "unprognostic (4.49e-2)" "unprognostic (1.56e-3)" "unprognostic (7.81e-3)" "unprognostic (5.53e-2)" "unprognostic (3.84e-2)" "unprognostic (2.08e-2)" 27.0 146.3 98.9 43.7 103.0 115.7 64.1 105.6 118.1 58.3 127.5 85.1 257.8 22.6 26.0 352.8 89.7 96.6 24.3 98.3 91.0 203.5 269.2 26.5 67.9 100.2 97.6 11.1 85.4 110.3 20.8 33.6 95.6 43.9 59.3 13.0 192.2 71.1 5.2 51.1 274.4 11.6 92.2 61.1 78.2 22.5 102.0 57.7 21.4 10.0 89.2 25.7 103.3 106.1 102.1 82.6 40.4 42.1 23.9 17.5 179.9 24.1 22.4 60.3 58.2 259.6 59.6 22.2 23.9 51.4 32.3 142.2 69.8 46.4 28.3 25.9 66.2 167.4 210.9 350.8 48.6 110.3 108.9 14.4 25.6 48.0 20.6 124.9 50.2 65.8 54.0 115.9 93.8 572.4 262.5 246.7 36.1 286.3 47.6 28.0 45.4 100.6 83.5 71.7 34.6 45.3 25.2 450.7 51.9 110.4 873.8 87.3 17.0 18.7 53.5 43.8 40.2 200.0 98.9 40.9 30.2 145.4 11.2 581.6 91.9 440.8 421.5 133.0 279.8 58.6 255.5 360.4 87.8 52.1 147.5 266.1 318.8 308.8 172.1 90.8 309.0 345.9 98.9 103.0 105.6 118.1 98.3 91.0 100.2 97.6 95.6 92.2 102.0 106.1 12.3 6.4 17.2 29.0 41.8 46.1 21.4 128.7 50.1 2.2 135.3 78.7 17.8 163.0 120.8 31.3 4.2 74.5 122.9 295.8 66.5 194.9 15.8 61.8 7.8 12.0 18.7 24.8 0.4 99.0 56.6 24.7 45.3 85.0 25.3 7.3 7.9 190.6 85.4 5.0 0.5 58.0 105.8 25.7 18.8 9.9 8.7 43.5 28.4 3.7 27.0 86.2 203.9 5.0 11.4 76.5 143.8 41.8 151.1 27.5 536.9 433.0 76.0 5.0 6.6 27.6 20.0 22.5 19.5 303.4 57.4 111.5 126.1 17.1 57.1 34.6 SLIRP "C14orf156, DC50" ENSG00000119705 "SRA stem-loop interacting RNA binding protein" Q9GZT3 14 77708071-77761104 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1099.6;Proximal tubular cells: 1027.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020291 Approved Supported Mitochondria No Yes 32000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA020291: AB_1845563" "unprognostic (9.28e-2)" "unprognostic (4.88e-2)" "unprognostic (1.87e-1)" "unprognostic (3.62e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (4.88e-4)" "unprognostic (1.18e-1)" "unprognostic (8.23e-2)" "unprognostic (2.19e-1)" "unprognostic (1.14e-2)" "unprognostic (1.92e-2)" "unprognostic (1.35e-1)" "unprognostic (9.95e-3)" "unprognostic (1.52e-1)" "unprognostic (2.39e-1)" "unprognostic (3.60e-2)" "unprognostic (1.37e-1)" 121.9 131.0 241.0 80.4 251.7 122.7 155.0 250.5 391.0 92.8 228.9 161.3 112.5 91.5 196.3 163.7 89.6 68.3 336.8 249.8 251.6 203.0 211.2 81.1 82.8 251.4 247.5 82.0 110.5 145.2 120.2 91.9 248.6 95.7 141.3 109.9 105.0 90.3 364.5 92.1 107.6 97.0 248.2 92.9 140.2 122.9 245.9 97.4 94.6 442.3 113.5 123.8 101.8 261.2 422.5 867.3 340.9 330.8 226.0 227.7 441.2 240.0 234.8 484.1 419.6 1187.1 387.1 314.2 238.9 284.7 295.6 415.7 645.4 508.0 647.3 166.5 717.2 316.3 816.1 1199.5 343.4 211.8 216.6 242.5 332.3 387.3 428.2 232.4 408.7 403.2 321.2 172.8 430.0 1442.6 325.3 562.2 525.1 938.0 1211.5 294.8 282.9 345.6 508.8 840.3 425.5 274.1 253.3 533.0 360.3 373.7 555.7 360.9 227.0 237.1 422.5 254.0 416.9 184.8 374.7 605.0 325.7 407.2 309.6 88.9 276.1 103.9 105.2 275.3 112.0 169.4 139.0 104.6 239.8 143.1 143.4 120.3 87.8 93.3 288.8 247.4 154.9 216.2 241.0 251.7 250.5 391.0 249.8 251.6 251.4 247.5 248.6 248.2 245.9 261.2 130.4 109.0 140.0 8.5 112.3 178.8 164.5 542.9 92.8 68.8 168.8 154.3 1099.6 270.2 303.9 264.8 47.9 393.0 82.7 330.9 770.9 405.1 548.5 163.7 141.9 169.0 246.8 203.2 10.8 530.1 382.3 166.0 119.3 123.7 171.5 73.1 179.2 793.4 313.6 43.7 9.6 373.1 388.6 202.8 119.5 123.0 168.0 135.2 250.8 2.8 211.4 206.4 93.7 8.5 16.7 440.6 334.4 170.0 136.9 190.5 563.3 1027.1 254.5 126.8 170.9 178.6 202.7 382.6 210.3 178.5 214.4 240.5 80.6 84.7 404.0 163.8 SMAD3 "HsT17436, JV15-2, MADH3" ENSG00000166949 "SMAD family member 3" P84022 15 67063763-67195173 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Aortic aneurysm, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 162.5;Prostatic glandular cells: 149.3;Urothelial cells: 276.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008094, HPA046386, HPA067203, CAB069409" Approved Supported Nucleoplasm,Cytosol NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm Cytosol "CAB008094: AB_2302271, CAB069409: AB_1622941, HPA046386: AB_2679647, HPA067203: AB_2685803" "unprognostic (1.04e-1)" "unprognostic (1.83e-1)" "unprognostic (1.06e-1)" "unprognostic (1.99e-2)" "unprognostic (1.61e-1)" "unprognostic (1.98e-2)" "unprognostic (8.40e-3)" "unprognostic (1.80e-2)" "unprognostic (7.62e-2)" "unprognostic (6.82e-2)" "prognostic unfavorable (2.48e-4)" "unprognostic (2.93e-1)" "unprognostic (2.14e-2)" "unprognostic (3.10e-1)" "unprognostic (1.79e-1)" "unprognostic (1.15e-1)" "unprognostic (5.97e-2)" 30.0 6.3 17.9 15.8 22.4 18.8 22.2 6.8 16.1 32.2 31.5 15.4 17.7 20.3 13.6 51.9 23.3 21.2 28.1 16.1 9.3 35.7 19.8 21.4 16.8 17.0 9.0 30.7 18.2 10.5 14.5 16.8 9.3 24.4 12.9 6.2 17.2 13.8 55.0 29.1 21.6 21.1 10.9 15.4 22.2 3.9 12.9 19.6 30.2 39.0 25.7 43.6 31.5 8.5 49.3 157.0 30.6 13.9 50.8 115.9 22.5 27.6 114.0 37.8 30.7 33.7 125.3 16.5 36.6 79.4 169.8 111.3 31.2 116.9 38.1 13.1 11.9 1.8 43.4 26.2 38.2 6.6 2.7 106.5 26.7 33.2 27.7 83.2 128.2 5.2 40.3 40.8 47.1 24.2 1.5 26.0 17.7 26.1 50.5 1.6 9.1 5.9 25.2 149.4 0.8 10.3 36.6 19.5 32.5 59.2 5.3 30.2 109.4 50.4 47.1 36.5 31.7 16.5 5.0 21.0 45.8 7.0 45.9 0.0 1.0 2.3 3.2 0.9 3.3 1.2 3.6 3.4 1.0 2.8 1.6 1.4 0.0 0.3 0.9 1.5 1.9 1.1 17.9 22.4 6.8 16.1 16.1 9.3 17.0 9.0 9.3 10.9 12.9 8.5 18.2 48.1 19.9 28.4 33.9 89.0 90.2 70.6 53.5 10.8 13.3 10.5 12.2 17.2 49.6 36.8 6.2 1.1 19.7 48.2 3.9 61.9 1.0 23.6 30.2 26.6 3.5 9.1 63.2 50.7 4.2 42.6 28.5 75.2 24.1 162.5 11.4 12.6 10.7 0.0 6.9 13.0 24.4 6.2 40.8 5.7 26.8 18.8 21.4 67.5 9.7 8.5 20.6 140.2 1.3 99.7 49.2 20.7 10.6 149.3 34.2 14.0 52.2 0.6 26.3 28.9 27.5 0.6 2.3 70.3 48.9 1.6 21.6 18.8 16.6 276.2 SMC4 "CAP-C, hCAP-C, SMC4L1" ENSG00000113810 "Structural maintenance of chromosomes 4" Q9NTJ3 3 160399274-160434954 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 60.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 305.8;Spermatocytes: 339.8;Spermatogonia: 239.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "basophil: 74.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029449, CAB055509" Approved Supported "Nuclear speckles,Cytosol" NA Yes 25000 "Cluster 18: Basophils - Vesicular transport" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles, Cytosol" "CAB055509: , HPA029449: AB_10603891" "unprognostic (2.63e-1)" "unprognostic (1.01e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (7.63e-4)" "unprognostic (2.22e-1)" "unprognostic (1.28e-2)" "prognostic unfavorable (2.94e-4)" "unprognostic (9.54e-2)" "unprognostic (2.18e-2)" "unprognostic (5.47e-2)" "prognostic unfavorable (4.20e-5)" "prognostic unfavorable (9.00e-4)" "prognostic unfavorable (8.05e-7)" "unprognostic (3.03e-2)" "unprognostic (4.46e-1)" "unprognostic (1.06e-1)" "unprognostic (4.98e-2)" 6.8 6.5 1.0 21.2 2.0 36.3 6.8 1.2 1.7 6.3 1.5 13.2 14.0 7.4 2.3 23.5 4.5 7.6 7.3 0.9 1.9 5.9 7.8 11.8 37.1 1.7 1.4 5.9 7.8 3.8 2.0 16.2 1.6 5.8 14.9 7.7 4.6 5.0 3.6 11.0 15.4 10.1 1.3 14.7 11.8 32.5 1.9 60.6 9.0 6.8 31.6 9.6 4.3 3.2 386.3 72.8 155.0 73.0 31.5 30.9 72.1 181.2 88.8 206.0 176.8 94.4 209.7 236.6 101.9 81.1 140.0 212.5 183.0 95.0 332.4 297.9 113.8 234.7 123.3 33.6 17.3 158.3 182.6 14.6 13.3 114.4 96.5 78.5 94.8 103.2 130.3 272.2 133.9 78.3 183.2 44.4 91.8 106.7 149.3 180.1 238.8 177.3 43.4 54.8 93.7 94.0 141.4 135.1 65.5 76.6 156.9 128.6 84.8 132.2 105.2 119.9 349.8 181.1 192.2 412.0 96.7 166.9 151.9 74.4 6.0 23.6 11.5 8.9 11.4 17.2 18.2 14.3 6.6 15.0 11.4 10.2 10.8 15.3 15.9 11.7 30.3 9.5 1.0 2.0 1.2 1.7 0.9 1.9 1.7 1.4 1.6 1.3 1.9 3.2 24.6 105.8 174.0 3.9 43.7 40.8 18.2 33.1 30.7 14.9 21.5 21.0 41.3 25.8 35.0 35.0 8.4 74.6 54.4 41.4 3.9 20.9 48.6 35.2 27.0 44.8 30.1 305.8 3.5 14.7 138.1 50.7 32.6 36.1 79.1 77.3 38.2 20.4 61.3 0.0 2.9 44.5 24.4 29.7 43.5 28.3 25.1 36.4 17.8 17.8 39.3 9.3 46.4 3.5 30.1 13.5 26.5 48.2 95.9 14.1 25.9 8.6 25.4 25.8 131.5 21.7 73.2 339.8 239.4 58.1 35.7 34.1 58.4 34.6 69.7 19.1 SMCO4 "C11orf75, FN5" ENSG00000166002 "Single-pass membrane protein with coiled-coil domains 4" Q9NRQ5 11 93478472-93543391 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 195.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 211.3;Paneth cells: 165.3;Proximal enterocytes: 200.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 113.7" "Low region specificity" "Detected in all" HPA041120 Uncertain NA Yes "Cluster 7: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 45: Enterocytes - Digestion" "HPA041120: AB_2677309" "unprognostic (7.45e-2)" "unprognostic (1.70e-3)" "unprognostic (2.54e-1)" "unprognostic (1.01e-2)" "unprognostic (1.58e-1)" "unprognostic (6.47e-2)" "unprognostic (8.56e-2)" "unprognostic (1.93e-1)" "unprognostic (3.43e-1)" "unprognostic (5.51e-1)" "unprognostic (4.23e-2)" "unprognostic (9.45e-2)" "prognostic unfavorable (5.81e-7)" "unprognostic (1.61e-1)" "unprognostic (3.05e-1)" "unprognostic (1.55e-2)" "unprognostic (5.01e-2)" 21.0 70.4 8.9 30.6 8.2 7.3 23.0 8.2 12.6 17.0 17.3 35.3 45.9 18.9 13.9 23.1 27.9 16.8 53.5 10.2 22.9 66.3 135.1 35.8 31.4 11.9 14.7 25.3 60.0 5.8 48.0 11.4 11.2 55.2 25.7 3.4 195.8 11.5 17.0 24.3 37.6 15.2 11.1 61.8 50.1 43.4 32.4 17.5 71.7 5.9 22.9 12.4 22.8 12.8 8.3 15.3 23.9 5.5 8.0 10.6 15.4 25.2 7.5 10.8 19.9 26.6 33.0 24.6 29.0 22.1 16.8 5.0 24.1 3.5 7.3 68.6 22.2 5.9 32.4 58.0 7.4 24.4 26.1 15.0 13.2 5.0 3.8 13.6 16.7 81.5 13.8 113.7 3.3 13.9 24.4 50.2 25.0 62.6 23.9 42.8 12.0 11.2 21.5 19.8 4.2 18.5 19.6 26.3 2.1 30.2 10.4 33.7 10.9 9.7 40.6 33.4 20.8 4.6 0.7 19.7 7.6 40.9 4.9 40.2 263.5 6.9 4.1 316.4 18.4 25.0 26.9 8.0 150.3 26.9 3.7 3.2 61.4 32.0 296.3 155.5 11.7 91.5 8.9 8.2 8.2 12.6 10.2 22.9 11.9 14.7 11.2 11.1 32.4 12.8 26.0 25.6 18.4 0.3 11.5 32.8 33.4 17.4 6.2 2.1 62.0 50.5 36.7 70.1 17.2 49.7 0.0 6.6 27.7 105.1 211.3 43.2 123.5 14.3 2.9 24.9 44.9 6.1 4.8 70.2 9.0 19.0 27.5 16.1 2.5 21.3 15.7 103.9 140.4 3.3 10.6 116.4 6.1 91.3 80.3 146.8 12.8 87.7 30.2 13.1 123.3 6.4 11.3 0.5 4.4 31.1 165.3 10.5 15.0 92.8 200.0 64.8 9.6 1.3 6.6 4.2 14.1 11.2 46.6 16.6 21.3 4.8 15.0 6.4 58.7 47.3 SMPD4 "FLJ20297, FLJ20756, KIAA1418, NET13, nSMase-3, NSMASE3" ENSG00000136699 "Sphingomyelin phosphodiesterase 4" Q9NXE4 2 130151392-130182750 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046279, HPA049426" Approved Approved "Nuclear membrane,Cytosol" NA Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 39: CACO-2 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nuclear membrane" Cytosol "HPA046279: AB_2679611, HPA049426: AB_2680762" "unprognostic (5.02e-2)" "unprognostic (9.61e-3)" "unprognostic (6.31e-2)" "prognostic unfavorable (7.47e-5)" "unprognostic (1.69e-1)" "unprognostic (8.80e-2)" "prognostic unfavorable (8.37e-6)" "unprognostic (3.27e-2)" "unprognostic (1.72e-1)" "unprognostic (7.47e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (1.73e-4)" "prognostic unfavorable (8.16e-8)" "unprognostic (1.74e-1)" "unprognostic (2.28e-1)" "unprognostic (1.47e-3)" "unprognostic (2.09e-1)" 9.9 10.8 4.2 11.1 4.9 25.4 10.9 5.3 6.2 15.5 3.1 12.1 9.5 15.5 5.0 13.8 15.9 9.2 11.7 4.0 7.0 8.6 9.2 10.6 15.7 7.5 5.0 14.6 13.3 15.2 22.7 14.9 6.3 11.8 11.1 4.7 12.9 11.7 13.3 13.5 11.5 12.9 2.4 11.2 10.3 17.7 6.0 19.8 16.0 12.0 15.7 11.8 12.3 10.0 89.1 41.5 46.2 39.2 29.1 21.8 58.7 41.5 42.0 76.3 62.8 119.2 47.0 56.2 41.2 49.9 36.3 43.8 64.0 64.4 40.4 72.7 61.2 60.5 36.2 90.1 31.2 68.5 34.7 25.6 39.4 77.0 27.2 21.1 44.9 51.4 82.2 40.8 40.7 44.3 72.2 32.0 77.0 40.1 56.4 74.3 44.2 59.0 27.0 38.6 66.8 36.3 42.8 54.5 22.7 24.9 37.8 34.8 32.8 57.0 49.3 33.0 49.4 34.3 44.0 79.2 51.4 38.7 44.0 1.8 9.2 14.8 12.9 11.2 14.3 8.9 9.6 11.6 9.6 9.1 9.0 10.5 4.3 12.1 8.1 6.0 9.2 10.4 4.2 4.9 5.3 6.2 4.0 7.0 7.5 5.0 6.3 2.4 6.0 10.0 17.4 3.2 11.3 4.9 20.8 15.0 9.1 8.8 12.0 19.8 21.5 23.0 3.9 5.7 8.0 7.3 12.5 23.8 16.4 7.9 9.8 9.2 22.7 16.0 19.7 12.0 13.1 21.2 6.9 12.2 26.5 12.2 18.8 26.3 6.3 29.0 10.4 17.3 14.1 15.2 6.7 12.8 4.1 13.2 7.7 41.7 14.6 10.2 16.0 1.0 8.8 9.9 11.3 7.5 10.4 11.8 10.5 18.4 27.0 9.4 7.7 5.9 9.9 16.0 0.0 14.1 12.8 25.0 25.6 18.7 20.6 15.6 15.6 16.0 15.2 9.6 SMTN ENSG00000183963 Smoothelin P53814 22 31064105-31104757 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 887.2;urinary bladder: 450.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 283.5;Hepatic stellate cells: 121.3;Sertoli cells: 184.1;Smooth muscle cells: 116.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "WM-115: 200.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001721, HPA051778, HPA058590" Enhanced Supported "Nucleoplasm,Actin filaments" No Yes 140000 "Cluster 30: Non-specific - Translation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "Actin filaments" "CAB001721: , HPA051778: AB_2681607, HPA058590: AB_2683765" "unprognostic (1.36e-2)" "unprognostic (4.84e-3)" "unprognostic (5.59e-2)" "unprognostic (1.96e-1)" "unprognostic (1.04e-1)" "unprognostic (1.41e-1)" "unprognostic (2.38e-3)" "unprognostic (1.08e-3)" "unprognostic (2.05e-2)" "unprognostic (4.56e-1)" "unprognostic (2.15e-1)" "unprognostic (7.22e-2)" "prognostic unfavorable (2.73e-5)" "unprognostic (2.75e-2)" "unprognostic (1.84e-1)" "unprognostic (8.41e-3)" "unprognostic (6.34e-2)" 54.7 19.2 10.8 25.3 12.5 4.7 42.2 10.3 13.1 100.2 7.6 887.2 30.0 251.0 7.0 65.1 132.4 20.8 152.0 9.0 9.3 35.6 15.3 38.2 5.6 11.7 12.5 34.0 25.2 3.3 9.8 17.4 11.0 150.9 29.2 15.2 16.3 177.9 95.7 38.7 151.5 127.2 10.5 54.5 231.2 12.5 12.4 2.9 26.4 26.2 2.5 450.6 91.5 10.0 73.0 21.2 7.2 27.0 11.0 17.2 58.0 106.8 49.1 85.7 58.4 29.9 22.4 32.1 9.3 59.3 17.3 10.6 7.2 62.8 40.4 10.6 58.2 33.9 18.3 36.1 9.7 51.5 57.4 14.2 5.8 114.0 18.7 29.2 74.7 12.3 37.3 25.9 59.6 64.5 5.9 11.4 8.2 36.1 90.0 20.3 20.5 34.6 34.5 23.2 11.5 12.7 33.4 15.9 15.7 7.4 18.8 8.2 118.7 62.1 58.4 59.4 79.8 24.6 32.5 18.8 91.0 19.7 200.5 0.0 1.0 0.0 0.1 0.2 0.0 1.3 0.1 0.3 0.4 0.0 1.0 0.5 0.1 0.1 0.2 0.2 0.0 0.6 10.8 12.5 10.3 13.1 9.0 9.3 11.7 12.5 11.0 10.5 12.4 10.0 94.5 6.4 3.3 23.8 2.0 65.1 33.5 16.1 19.4 46.6 18.6 26.7 39.5 5.7 6.1 9.2 283.5 13.4 2.7 12.8 9.8 14.8 1.2 4.0 52.1 62.8 29.2 0.0 0.2 20.1 68.8 35.9 18.3 7.3 0.0 11.0 121.3 2.6 6.0 5.0 1.9 29.9 14.2 6.8 14.6 1.9 22.4 4.7 14.2 7.5 1.0 31.2 1.0 4.5 2.0 73.2 11.4 48.5 2.1 21.7 5.6 18.4 2.2 54.0 184.1 18.4 116.4 5.7 7.9 9.7 69.3 21.9 3.7 16.3 27.0 14.9 SOGA1 "C20orf117, dJ132F21.1, FLJ44670, KIAA0889, SOGA" ENSG00000149639 "Suppressor of glucose, autophagy associated 1" O94964 20 36777447-36863538 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 63.9" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 54.8;Oligodendrocytes: 50.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043992 Approved Approved Nucleoli,Cytosol "Secreted to blood" NA Yes "Cluster 21: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Nucleoli, Cytosol" "HPA043992: AB_2678762" "unprognostic (2.34e-2)" "unprognostic (1.35e-1)" "unprognostic (6.58e-2)" "unprognostic (1.73e-2)" "unprognostic (1.51e-1)" "unprognostic (1.48e-1)" "unprognostic (2.27e-3)" "unprognostic (1.37e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (8.28e-5)" "unprognostic (1.09e-3)" "unprognostic (2.85e-1)" "prognostic unfavorable (4.49e-4)" "unprognostic (6.99e-2)" "unprognostic (4.16e-2)" "unprognostic (1.40e-2)" "unprognostic (4.45e-3)" 6.6 14.2 13.4 3.6 18.1 1.1 6.2 63.9 16.4 9.5 0.0 12.3 1.9 10.9 3.8 7.0 9.6 4.8 9.5 12.8 14.4 7.8 0.9 6.2 2.5 14.6 15.0 10.4 2.8 7.3 4.9 6.2 12.6 9.0 2.8 4.5 4.7 8.8 2.4 8.6 5.8 8.4 8.8 4.6 6.4 7.9 15.1 2.9 12.2 3.9 3.1 11.2 7.4 21.9 13.4 18.0 21.5 23.2 12.2 11.2 5.6 11.6 12.5 16.1 9.5 7.3 2.1 6.0 4.2 20.4 14.0 17.8 17.3 10.8 16.8 0.9 3.4 9.7 18.5 9.7 6.4 2.1 9.0 6.3 13.0 15.4 10.9 7.0 10.6 6.5 6.9 1.2 17.8 13.0 6.9 5.1 5.5 1.3 13.8 16.1 19.9 2.3 9.5 4.0 25.5 15.9 24.1 26.1 7.5 9.4 33.3 14.4 16.3 40.2 7.7 19.9 25.7 2.4 0.6 5.8 17.1 2.8 26.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.0 13.4 18.1 63.9 16.4 12.8 14.4 14.6 15.0 12.6 8.8 15.1 21.9 16.5 0.0 1.8 18.9 4.4 12.6 5.4 6.3 13.6 26.3 9.6 8.9 16.1 5.7 6.7 20.2 37.5 15.6 11.3 1.7 1.9 3.8 0.9 8.6 20.5 14.5 6.0 1.3 19.9 1.5 10.2 12.0 0.5 21.9 10.8 33.0 10.4 0.6 10.0 23.5 30.3 1.5 0.0 7.6 10.7 2.4 12.2 8.1 5.4 21.5 4.5 17.8 0.0 54.8 50.9 1.4 2.4 18.8 1.8 6.0 2.1 1.5 3.9 3.8 13.1 23.2 16.9 0.5 1.3 13.7 16.1 3.3 1.4 14.0 3.0 2.9 SOX4 ENSG00000124766 "SRY-box transcription factor 4" Q06945 6 21593751-21598619 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 73.4" "Cell type enhanced" "Detected in many" "Ductal cells: 1128.5;Granulosa cells: 1047.5;Ionocytes: 1320.3;Pancreatic endocrine cells: 1288.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 45.7" "Group enriched" "Detected in all" 5 "dendritic cells: 45.7;granulocytes: 33.3;monocytes: 22.0" "Cell line enhanced" "Detected in many" "AN3-CA: 254.1;MOLT-4: 229.9" "Region enhanced" "Detected in all" "olfactory bulb: 54.2" HPA029901 Approved Supported Nucleoplasm,Mitochondria NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm Mitochondria "HPA029901: AB_10601592" "unprognostic (4.01e-2)" "unprognostic (3.06e-1)" "unprognostic (9.28e-2)" "unprognostic (5.18e-2)" "unprognostic (5.00e-2)" "unprognostic (1.08e-2)" "prognostic unfavorable (2.57e-5)" "unprognostic (1.78e-1)" "unprognostic (8.01e-3)" "unprognostic (1.98e-2)" "unprognostic (3.88e-3)" "unprognostic (1.18e-1)" "unprognostic (8.73e-3)" "unprognostic (3.66e-2)" "unprognostic (3.31e-1)" "unprognostic (2.01e-1)" "unprognostic (9.27e-2)" 11.8 4.3 4.7 9.2 5.0 24.0 17.9 8.8 6.7 21.5 2.8 11.9 12.5 57.8 15.0 5.4 13.5 20.4 6.4 4.2 6.5 16.8 6.4 19.3 5.8 3.5 5.0 51.7 10.2 3.6 4.1 6.1 4.1 14.5 14.4 6.4 17.5 6.8 3.5 8.8 11.6 17.4 4.0 5.4 17.5 9.9 7.1 73.4 8.6 6.1 7.4 21.1 7.7 4.2 8.5 24.4 60.5 254.1 22.0 5.5 98.7 3.8 7.8 4.6 4.1 16.7 16.5 2.9 100.2 6.2 3.5 25.1 32.0 17.9 3.3 36.6 66.8 2.7 11.5 11.2 3.5 9.0 2.1 9.6 18.1 2.1 7.3 64.1 72.3 138.8 0.6 0.2 5.2 20.6 229.9 21.6 45.3 12.7 23.1 99.7 5.3 0.4 44.1 78.3 78.9 141.2 35.9 41.1 14.0 74.9 20.1 30.9 55.7 7.1 23.1 1.7 18.6 1.5 0.1 71.8 2.4 30.6 28.5 33.3 19.3 2.1 0.5 11.7 0.1 7.0 0.3 0.3 8.7 6.6 2.2 1.6 0.8 7.4 22.0 45.7 2.1 4.7 4.7 5.0 8.8 6.7 4.2 6.5 3.5 5.0 4.1 4.0 7.1 4.2 235.0 198.7 50.4 0.7 36.2 112.5 129.2 660.7 676.7 99.7 586.1 676.5 297.4 423.2 457.3 154.5 12.5 74.8 104.4 247.6 66.5 1128.5 6.1 669.0 624.2 264.5 340.8 114.3 3.2 604.4 409.4 247.3 313.0 650.9 60.6 1047.5 119.2 6.8 35.5 48.8 4.6 263.0 1320.3 78.0 266.7 12.2 12.2 94.0 243.7 3.7 91.4 189.1 17.5 70.4 1.0 1288.2 153.8 11.3 40.9 151.1 76.7 132.5 162.1 31.6 6.6 234.2 439.9 4.9 236.8 400.7 93.1 30.2 36.6 69.6 299.4 272.5 SPAG5 "DEEPEST, hMAP126, MAP126" ENSG00000076382 "Sperm associated antigen 5" Q96R06 17 28577565-28599025 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.9;kidney: 37.8;testis: 74.0" "Cell type enhanced" "Detected in many" "Early spermatids: 126.0;Erythroid cells: 37.2;Spermatocytes: 72.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 11.7;T-reg: 4.9" "Group enriched" "Detected in many" 6 "granulocytes: 11.7;T-cells: 4.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA022008, HPA022479, HPA024418" Approved Supported "Nuclear bodies,Mitotic spindle,Cytosol" Yes Yes "Cluster 34: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies, Mitotic spindle" Cytosol "HPA022008: AB_1853519, HPA022479: AB_1853521, HPA024418: " "unprognostic (4.71e-2)" "unprognostic (1.32e-1)" "unprognostic (5.31e-3)" "unprognostic (2.32e-3)" "unprognostic (3.50e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (5.43e-5)" "unprognostic (3.37e-3)" "unprognostic (4.84e-3)" "unprognostic (5.97e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (3.49e-2)" "prognostic unfavorable (5.43e-13)" "unprognostic (2.64e-1)" "unprognostic (1.66e-1)" "unprognostic (2.90e-2)" "unprognostic (2.01e-1)" 2.2 3.3 7.8 7.8 7.6 37.9 2.4 5.8 9.1 2.6 3.4 8.3 7.9 1.9 2.4 8.3 1.7 1.8 1.4 7.6 7.7 37.8 14.8 3.4 14.5 6.7 6.8 2.7 1.5 1.1 4.3 5.7 6.7 2.2 10.7 10.8 2.4 0.8 1.0 5.5 9.1 3.4 5.0 7.4 3.6 74.0 7.7 22.4 8.7 0.7 17.3 2.6 3.6 7.5 84.7 87.7 103.3 78.4 5.2 8.6 42.4 65.9 42.4 98.1 78.3 69.2 25.5 59.8 34.2 46.8 91.7 70.2 114.5 42.7 103.8 108.6 72.9 62.9 87.9 80.2 0.6 83.1 76.1 2.9 3.8 78.6 40.4 14.5 52.1 90.6 69.7 101.5 80.7 52.6 109.4 92.9 54.2 68.3 44.5 72.1 144.4 70.9 29.0 43.0 78.6 45.8 96.4 114.9 31.6 84.9 82.2 70.6 25.7 56.4 91.3 46.6 114.6 46.7 72.9 87.3 37.8 60.6 91.8 11.7 0.0 0.0 0.4 0.4 0.7 0.6 1.2 0.9 0.1 1.4 1.1 0.9 0.2 0.8 0.3 0.3 4.9 0.9 7.8 7.6 5.8 9.1 7.6 7.7 6.7 6.8 6.7 5.0 7.7 7.5 0.5 3.2 1.7 0.7 3.3 2.0 0.9 1.3 1.2 5.0 1.1 1.0 0.7 0.0 1.9 0.0 0.0 9.0 1.3 4.7 1.9 0.5 126.0 6.0 1.1 1.5 13.1 37.2 5.2 0.4 12.2 2.6 5.1 1.8 1.3 12.6 3.3 6.3 6.5 3.3 6.0 4.6 4.1 2.7 4.0 25.2 0.9 6.1 0.0 1.9 0.9 0.7 0.0 2.0 1.7 0.4 4.7 0.0 13.1 0.8 8.1 12.5 7.7 3.9 6.6 2.0 2.2 72.6 21.0 5.2 1.0 3.8 2.8 0.9 5.1 1.1 SPC24 "FLJ90806, SPBC24" ENSG00000161888 "SPC24 component of NDC80 kinetochore complex" Q8NBT2 19 11131520-11155808 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.0;lymphoid tissue: 14.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 35.0;Extravillous trophoblasts: 15.5;Hofbauer cells: 14.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA051234 Approved Supported Nucleoplasm,Nucleoli NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "HPA051234: AB_2681397" "unprognostic (1.57e-1)" "prognostic favorable (3.59e-4)" "unprognostic (6.79e-2)" "unprognostic (1.07e-3)" "unprognostic (4.04e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (1.46e-4)" "unprognostic (1.21e-2)" "unprognostic (1.69e-2)" "unprognostic (1.12e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (6.12e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.62e-2)" "unprognostic (3.52e-2)" "unprognostic (2.25e-1)" "unprognostic (8.82e-2)" 1.9 1.7 1.3 4.8 1.5 26.0 1.2 3.9 2.1 2.1 1.7 4.7 4.5 2.7 0.8 5.0 1.3 2.3 2.7 1.6 1.5 0.8 1.6 1.6 6.3 1.1 0.8 1.3 1.1 0.4 0.4 3.2 1.3 1.6 4.3 1.2 1.3 2.0 4.0 3.9 4.1 8.1 0.5 3.1 2.9 4.3 1.4 14.7 0.9 1.1 6.5 2.5 2.0 2.4 73.6 26.9 36.9 30.1 5.0 9.7 16.6 42.3 15.7 38.6 43.6 28.4 24.6 58.2 46.0 18.5 22.8 38.8 29.0 30.3 28.7 30.9 24.9 78.5 68.9 43.2 1.1 55.5 33.7 1.9 1.1 27.8 12.8 10.0 34.7 62.3 42.8 118.3 27.6 48.7 76.4 32.9 25.5 19.8 43.9 59.8 56.7 18.6 11.2 23.8 38.4 27.2 37.0 22.4 9.6 17.5 22.0 19.8 33.2 36.8 38.3 49.6 51.2 70.5 39.8 55.6 26.9 53.9 30.5 1.9 0.4 0.4 0.5 0.5 0.4 0.8 0.9 1.5 0.2 0.7 0.9 0.6 2.2 2.0 0.5 0.5 1.7 0.3 1.3 1.5 3.9 2.1 1.6 1.5 1.1 0.8 1.3 0.5 1.4 2.4 0.2 0.0 0.5 0.3 1.5 1.1 1.2 1.3 0.0 0.0 1.0 0.4 9.0 1.5 0.8 5.5 6.2 10.0 0.9 2.8 0.0 0.2 0.3 1.0 2.2 2.2 2.4 35.0 0.3 0.0 15.5 3.5 3.6 1.8 5.7 6.5 4.6 0.7 14.0 0.0 0.3 2.6 0.0 3.0 2.5 3.0 0.6 1.0 0.0 1.0 0.0 2.1 2.1 0.5 0.3 0.3 0.0 0.4 6.3 0.3 0.7 0.6 0.2 0.6 0.0 1.3 2.4 6.9 10.8 2.1 0.3 2.1 2.2 0.5 6.6 1.2 SPC25 "AD024, MGC22228, SPBC25" ENSG00000152253 "SPC25 component of NDC80 kinetochore complex" Q9HBM1 2 168834132-168913371 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 23.5;Erythroid cells: 29.9;Extravillous trophoblasts: 37.9;Muller glia cells: 17.2;Spermatocytes: 26.2;Spermatogonia: 20.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047144, HPA050544" Enhanced Enhanced Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA047144: AB_2679952, HPA050544: " "unprognostic (3.52e-2)" "unprognostic (2.28e-2)" "unprognostic (2.23e-1)" "prognostic unfavorable (8.61e-5)" "unprognostic (3.15e-1)" "unprognostic (1.84e-2)" "prognostic unfavorable (4.74e-6)" "prognostic unfavorable (9.44e-5)" "unprognostic (1.84e-3)" "unprognostic (7.58e-2)" "unprognostic (1.36e-1)" "unprognostic (1.30e-2)" "unprognostic (1.11e-16)" "unprognostic (9.91e-3)" "unprognostic (1.85e-1)" "unprognostic (3.43e-1)" "unprognostic (1.57e-1)" 0.6 0.8 0.6 0.7 0.6 4.2 1.0 0.3 1.5 0.7 0.5 2.1 3.7 0.5 0.0 4.4 0.3 0.5 0.4 1.6 0.7 1.1 0.8 0.9 3.9 0.6 0.7 0.5 1.3 0.1 0.1 1.1 0.8 0.4 1.6 1.7 1.0 0.0 0.6 1.1 2.1 1.0 0.1 2.1 1.6 3.4 0.6 8.5 0.2 0.1 3.7 0.5 1.5 1.8 1.0 16.8 40.6 22.8 1.8 1.9 14.5 22.9 9.3 23.5 18.1 5.6 16.2 15.7 9.0 3.4 31.9 20.9 15.9 0.0 20.7 10.0 21.5 30.2 7.2 2.2 0.1 20.3 8.9 0.3 1.0 14.3 0.0 4.7 10.3 28.2 0.8 15.7 6.4 9.8 16.1 26.3 0.9 11.2 21.0 28.8 38.1 5.6 9.6 13.7 30.4 0.5 16.8 14.4 3.9 13.5 0.4 16.4 2.5 3.6 42.1 13.4 18.2 31.4 56.0 12.5 4.1 0.5 14.3 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.1 0.6 0.6 0.3 1.5 1.6 0.7 0.6 0.7 0.8 0.1 0.6 1.8 0.4 0.0 1.1 0.7 4.2 5.4 1.5 7.1 1.2 0.0 1.5 2.4 0.6 0.0 2.6 0.0 0.0 23.5 1.5 3.7 0.0 0.2 2.0 0.5 1.8 1.6 0.0 29.9 0.3 0.0 37.9 4.6 2.0 1.8 0.0 10.1 2.9 1.2 15.1 0.0 0.5 5.2 2.0 1.9 2.4 1.6 0.6 2.0 0.0 0.0 0.0 17.2 0.0 5.0 0.2 0.5 0.1 1.2 15.3 1.0 1.0 0.2 0.1 0.6 0.0 1.3 4.4 26.2 20.1 7.3 1.4 5.7 2.7 1.7 9.9 2.5 SPDL1 "CCDC99, FLJ20364, hSpindly" ENSG00000040275 "Spindle apparatus coiled-coil protein 1" Q96EA4 5 169583636-169604778 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 35.5" "Cell type enhanced" "Detected in many" "Granulosa cells: 38.4;Spermatocytes: 112.9;Spermatogonia: 59.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA044700, HPA048146" Enhanced Approved Cytosol NA Yes "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA044700: AB_2679052, HPA048146: AB_2680284" "unprognostic (2.61e-2)" "unprognostic (1.94e-1)" "unprognostic (8.59e-3)" "prognostic unfavorable (1.18e-4)" "unprognostic (4.24e-1)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.48e-6)" "unprognostic (2.63e-3)" "unprognostic (5.70e-3)" "unprognostic (8.27e-3)" "prognostic unfavorable (1.19e-5)" "unprognostic (2.92e-2)" "prognostic unfavorable (2.13e-6)" "unprognostic (2.81e-1)" "unprognostic (3.13e-1)" "unprognostic (3.28e-2)" "unprognostic (2.93e-1)" 3.9 3.6 5.5 9.4 6.0 10.9 5.5 6.1 7.2 3.4 3.4 5.4 5.7 6.2 3.8 5.8 4.4 4.5 3.4 4.7 5.6 4.8 3.2 4.0 14.9 6.0 5.5 6.7 2.5 5.0 2.4 8.4 6.1 3.3 5.7 3.4 3.2 3.1 5.3 5.5 5.3 7.4 7.1 6.6 5.3 35.5 5.4 21.5 4.3 5.9 14.0 4.8 3.8 7.2 57.0 69.2 67.4 47.6 17.6 18.5 59.1 181.1 22.9 128.1 119.0 89.6 38.8 54.3 116.9 147.0 90.3 39.3 56.8 76.0 139.6 58.1 65.2 59.6 117.0 36.2 8.3 66.9 51.3 9.2 6.2 62.2 34.0 29.0 59.9 60.5 41.3 39.3 142.4 58.5 54.1 28.2 50.1 28.9 63.2 64.8 67.6 38.5 89.7 19.8 43.7 31.4 84.9 23.6 34.5 46.9 27.0 44.9 46.3 146.6 46.8 43.4 140.0 30.1 69.2 69.1 35.4 61.9 50.2 4.0 2.7 3.8 8.4 3.6 8.9 11.2 7.9 8.9 2.8 12.7 10.8 9.1 0.5 8.4 6.2 19.7 8.6 4.1 5.5 6.0 6.1 7.2 4.7 5.6 6.0 5.5 6.1 7.1 5.4 7.2 6.1 3.2 6.3 3.9 8.7 4.0 1.7 4.8 4.6 6.9 6.2 7.5 7.1 2.8 7.0 1.8 0.0 14.1 9.8 3.6 5.9 6.6 9.6 5.3 8.0 6.5 1.8 22.3 6.2 4.8 26.1 7.7 12.2 4.9 8.8 38.4 13.2 3.2 12.2 3.3 6.5 3.2 2.0 4.7 3.6 11.1 4.4 4.7 3.6 2.8 5.0 7.4 13.4 5.0 6.8 6.6 1.9 6.4 10.2 1.6 0.5 8.2 4.1 4.4 6.6 6.4 9.9 112.9 59.2 5.8 4.4 4.9 5.2 9.6 7.4 2.5 SPIN4 "FLJ44984, TDRD28" ENSG00000186767 "Spindlin family member 4" Q56A73 X 63347228-63351332 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "NK-cell: 2.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA044559 Uncertain Approved Nucleoli,Cytosol NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol Nucleoli "HPA044559: AB_10794171" "unprognostic (9.66e-2)" "unprognostic (2.00e-1)" "unprognostic (1.90e-1)" "unprognostic (2.21e-2)" "unprognostic (2.31e-1)" "unprognostic (3.12e-1)" "unprognostic (3.22e-4)" "unprognostic (3.30e-3)" "unprognostic (9.44e-3)" "unprognostic (8.62e-2)" "unprognostic (3.65e-3)" "unprognostic (9.39e-2)" "prognostic unfavorable (3.56e-6)" "unprognostic (1.74e-2)" "unprognostic (2.15e-1)" "unprognostic (2.57e-1)" "unprognostic (8.09e-2)" 1.8 1.7 1.4 2.7 1.3 10.2 3.3 0.9 1.7 2.4 1.7 3.6 2.2 3.4 2.3 5.9 2.7 2.1 1.3 1.3 3.1 1.5 1.3 3.1 3.5 1.6 2.0 2.9 1.7 1.7 2.3 4.4 1.6 3.3 4.1 2.0 7.2 1.7 0.5 2.0 2.2 3.5 1.2 2.8 2.2 0.7 2.5 3.1 2.5 0.5 5.6 2.1 2.7 1.8 31.7 8.0 18.2 14.9 3.9 5.5 13.1 15.6 6.5 8.9 10.6 5.4 30.7 0.0 6.7 7.3 10.2 10.3 23.7 11.2 16.2 13.7 7.5 40.5 10.3 4.9 1.7 35.5 30.3 2.6 3.9 14.9 8.0 4.3 9.9 7.0 12.5 38.2 20.4 10.7 11.9 19.0 18.8 5.2 11.5 16.4 39.2 8.7 6.5 8.3 0.1 10.0 27.9 8.1 3.0 37.4 17.4 16.9 4.3 17.9 19.9 29.8 9.8 8.4 10.4 20.5 9.5 28.8 10.7 0.7 0.8 1.6 0.5 0.9 0.2 0.4 0.3 0.3 0.6 0.4 0.1 0.4 0.0 2.6 0.8 0.0 0.2 0.4 1.4 1.3 0.9 1.7 1.3 3.1 1.6 2.0 1.6 1.2 2.5 1.8 3.0 0.0 2.0 2.3 2.9 3.3 1.4 3.5 6.2 5.7 6.0 4.3 1.5 1.5 5.8 3.7 2.1 6.1 3.9 3.6 1.9 0.6 0.0 3.4 3.2 5.1 6.7 11.1 2.4 1.4 6.8 3.4 2.0 2.1 9.5 3.5 8.6 1.3 2.6 1.7 3.3 6.7 4.1 1.0 2.1 0.4 3.1 2.2 5.4 1.9 1.1 1.3 5.2 3.0 4.5 1.3 6.3 3.4 0.7 2.3 0.6 1.3 5.7 2.8 0.0 2.5 2.6 0.1 0.5 9.8 6.3 3.3 3.1 4.3 5.7 5.7 SPTBN1 ENSG00000115306 "Spectrin beta, non-erythrocytic 1" Q01082 2 54456317-54671446 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 615.4;Peritubular cells: 663.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012685, HPA013149" Supported Approved "Golgi apparatus" NA Yes 1500000 "Cluster 39: Non-specific - mRNA processing" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "HPA012685: AB_1857433, HPA013149: AB_1857434" "unprognostic (2.72e-1)" "unprognostic (4.44e-3)" "unprognostic (3.00e-2)" "unprognostic (3.25e-1)" "unprognostic (4.09e-2)" "unprognostic (7.95e-2)" "unprognostic (9.24e-2)" "unprognostic (3.72e-2)" "unprognostic (7.31e-2)" "unprognostic (1.67e-1)" "unprognostic (2.26e-2)" "unprognostic (7.25e-2)" "prognostic favorable (2.59e-5)" "unprognostic (2.31e-1)" "unprognostic (2.73e-1)" "unprognostic (1.68e-3)" "unprognostic (5.18e-3)" 187.3 70.9 210.6 34.7 205.1 37.6 78.7 97.4 166.1 54.1 94.2 62.8 32.7 52.0 36.3 41.7 56.2 69.2 135.9 156.2 99.7 65.3 83.8 131.6 28.9 141.2 154.4 73.2 45.5 129.2 27.8 97.4 120.4 43.8 52.4 56.0 55.1 74.4 54.0 39.4 46.8 59.9 134.8 58.7 55.6 32.6 214.6 29.3 72.8 87.2 30.0 45.6 38.6 163.6 96.5 150.5 60.4 57.2 234.7 158.8 74.8 40.2 82.3 63.7 61.4 101.7 66.6 0.4 112.1 142.0 55.1 110.9 85.1 128.0 66.0 0.8 35.6 43.7 118.4 166.2 97.7 59.7 24.4 62.3 64.8 193.8 119.7 77.6 151.6 95.1 50.0 64.0 86.1 21.6 105.0 14.5 66.3 129.6 70.2 116.2 95.0 37.2 92.2 120.6 36.3 113.3 121.5 39.5 88.1 58.9 19.6 9.9 235.2 89.9 79.0 110.2 58.2 62.8 42.8 32.7 98.1 17.7 163.7 2.3 0.4 2.8 3.7 0.0 3.9 3.7 3.4 3.6 1.3 3.5 5.0 3.6 0.6 5.2 0.0 1.1 3.2 3.1 210.6 205.1 97.4 166.1 156.2 99.7 141.2 154.4 120.4 134.8 214.6 163.6 615.4 407.1 124.6 233.4 45.7 83.1 50.0 64.7 42.7 94.4 60.8 58.0 262.9 144.4 100.6 145.3 73.0 28.3 31.7 343.6 7.9 223.7 12.1 140.4 80.3 426.4 83.1 21.5 231.3 121.9 42.0 271.6 139.7 115.7 35.4 68.2 228.5 184.6 14.2 141.3 195.4 135.5 77.3 17.7 47.0 31.5 503.2 16.6 147.7 294.2 9.7 131.9 36.0 154.8 283.1 243.3 109.9 663.5 76.3 75.6 142.8 44.1 187.3 93.6 164.3 340.3 171.9 54.7 53.3 79.7 68.2 11.1 49.2 56.6 151.9 88.1 SRSF10 "FUSIP1, FUSIP2, PPP1R149, SFRS13, SFRS13A, SRp38, SRrp40, TASR1, TASR2" ENSG00000188529 "Serine and arginine rich splicing factor 10" O75494 1 23964347-23980927 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053805, HPA053831" Uncertain Supported Nucleoplasm NA Yes 49000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA053805: AB_2682269, HPA053831: AB_2682275" "unprognostic (2.49e-1)" "unprognostic (3.10e-1)" "unprognostic (1.34e-2)" "unprognostic (1.77e-1)" "unprognostic (1.46e-1)" "unprognostic (1.06e-2)" "prognostic unfavorable (1.18e-6)" "unprognostic (2.05e-2)" "unprognostic (1.68e-3)" "unprognostic (1.30e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.74e-4)" "prognostic unfavorable (1.01e-5)" "unprognostic (2.69e-2)" "unprognostic (1.59e-1)" "unprognostic (2.76e-1)" "unprognostic (2.40e-2)" 57.0 59.9 22.5 46.3 23.3 119.6 46.9 26.5 30.1 51.7 29.9 48.8 38.0 49.6 40.7 43.8 56.3 29.2 40.0 23.2 24.4 56.3 56.7 49.6 61.0 23.3 23.5 61.1 50.1 37.2 43.6 42.2 24.3 47.9 45.0 46.5 45.4 32.1 37.7 40.1 50.2 41.3 25.0 49.0 47.9 34.7 23.1 55.8 61.3 24.4 57.1 43.0 45.0 28.6 110.7 89.6 142.9 92.9 88.6 68.2 98.0 133.4 53.5 116.8 102.3 83.5 112.8 239.5 82.7 63.5 73.8 99.7 163.4 89.7 140.7 140.9 122.7 134.5 160.3 115.1 62.2 164.3 107.9 44.2 68.5 74.3 72.9 66.8 89.1 92.1 187.2 83.4 99.3 77.2 167.9 118.1 196.2 139.6 84.4 162.9 99.7 127.6 102.1 86.4 104.9 85.5 98.7 88.2 100.1 97.4 94.2 129.5 89.2 94.7 99.5 89.2 126.4 94.6 134.6 189.1 83.4 185.9 112.8 112.8 67.7 74.0 51.3 84.1 65.1 80.2 58.5 60.3 58.1 68.8 62.9 55.8 43.9 74.5 82.0 69.6 75.9 72.3 22.5 23.3 26.5 30.1 23.2 24.4 23.3 23.5 24.3 25.0 23.1 28.6 115.8 112.2 112.1 39.2 188.4 42.6 115.5 23.2 183.2 159.1 104.4 103.4 59.1 97.2 85.5 79.1 160.6 116.8 150.5 85.6 78.2 94.2 115.4 96.7 138.3 109.8 122.0 154.2 54.7 89.2 164.1 111.3 93.8 106.7 93.6 181.0 86.0 63.8 82.0 99.3 50.9 92.4 36.7 51.2 41.3 118.5 127.7 83.4 26.6 44.0 101.5 131.6 111.2 54.8 67.2 78.6 85.9 110.6 169.4 122.6 67.4 74.6 94.6 287.5 105.2 121.8 125.8 188.1 150.5 140.0 45.5 63.3 142.6 335.7 106.3 100.1 ST6GALNAC5 "MGC3184, SIAT7E, ST6GalNAcV" ENSG00000117069 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5" Q9BVH7 1 76867480-77067546 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5.9" "Group enriched" "Detected in some" 8 "Excitatory neurons: 480.3;Inhibitory neurons: 417.3" "Cancer enhanced" "Detected in many" "ovarian cancer: 10.9" "Region enhanced" "Detected in many" "cerebral cortex: 5.9;hippocampal formation: 5.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 4.7;fHDF/TERT166: 5.4;HaCaT: 2.7;SH-SY5Y: 4.1;U-2 OS: 4.4;U-251 MG: 2.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "hippocampal formation: 51.3" "HPA065593, HPA070354" Uncertain Approved Vesicles "Intracellular and membrane" NA Yes 180000 "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA065593: AB_2685515, HPA070354: AB_2686260" "unprognostic (1.32e-1)" "unprognostic (5.96e-2)" "unprognostic (1.72e-1)" "unprognostic (1.49e-2)" "unprognostic (2.82e-2)" "unprognostic (2.04e-2)" "unprognostic (4.67e-2)" "unprognostic (2.72e-2)" "unprognostic (3.60e-2)" "unprognostic (1.99e-1)" "unprognostic (1.61e-2)" "unprognostic (1.58e-1)" "unprognostic (2.10e-2)" "unprognostic (5.90e-3)" "unprognostic (9.66e-2)" "unprognostic (6.88e-2)" "unprognostic (1.69e-2)" 0.1 3.0 1.5 1.5 1.1 0.0 1.2 0.0 5.9 0.7 0.0 1.8 0.2 0.1 0.0 1.0 1.9 2.2 0.5 5.5 0.0 0.1 0.0 3.6 0.4 0.0 0.0 1.6 0.1 0.0 1.9 0.1 0.0 1.0 0.6 3.2 0.5 0.3 0.0 0.2 0.9 3.0 0.0 0.2 1.5 0.3 0.0 0.0 0.0 0.0 0.3 1.6 0.6 0.0 1.2 0.0 4.7 0.0 0.0 0.0 0.0 0.4 1.5 1.1 0.4 0.0 0.1 0.0 0.0 5.4 0.0 2.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.3 0.4 0.0 0.0 1.1 4.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 4.4 0.0 2.6 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.1 0.0 5.9 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.5 0.5 35.6 0.1 0.0 0.0 0.1 0.0 20.7 2.8 1.7 1.1 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.2 1.9 0.4 0.0 0.0 480.3 0.0 0.1 0.8 0.0 0.2 1.3 0.9 0.0 0.0 0.1 0.0 417.3 0.2 0.0 0.0 0.0 2.3 0.6 0.1 0.0 8.4 0.0 0.7 0.0 10.6 6.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 1.3 0.0 0.2 0.4 0.1 0.5 0.0 0.0 0.1 0.2 0.0 0.0 0.1 STARD4 ENSG00000164211 "StAR related lipid transfer domain containing 4" Q96DR4 5 111496033-111512590 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046177, HPA048081" Approved Approved "Plasma membrane" NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 9: Intestine - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 15: Hepatocytes - Hemostasis" "Plasma membrane" "HPA046177: AB_2679570, HPA048081: AB_2680253" "unprognostic (1.13e-1)" "unprognostic (7.07e-3)" "unprognostic (1.53e-2)" "unprognostic (1.64e-1)" "unprognostic (1.01e-1)" "unprognostic (1.21e-2)" "prognostic unfavorable (4.80e-5)" "unprognostic (1.31e-1)" "unprognostic (1.11e-1)" "unprognostic (4.26e-1)" "unprognostic (6.27e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (5.89e-5)" "unprognostic (2.00e-1)" "unprognostic (3.82e-3)" "unprognostic (4.01e-3)" "prognostic unfavorable (2.84e-4)" 6.2 15.8 8.3 15.9 15.8 19.4 3.9 25.2 12.6 10.2 11.5 14.7 40.8 7.7 16.2 8.5 5.0 9.7 15.0 9.5 10.6 8.5 34.1 20.9 12.6 16.0 16.7 6.5 6.1 14.4 8.2 27.3 13.8 20.7 16.9 12.0 6.6 9.9 1.5 2.5 35.7 6.9 10.1 12.1 17.9 6.8 14.8 7.2 9.0 1.7 10.1 7.7 9.2 11.3 20.6 10.0 48.2 29.4 42.4 84.0 16.3 21.0 46.6 29.8 89.1 37.7 59.9 24.5 8.4 13.4 89.0 9.1 24.8 71.8 28.8 23.7 10.4 19.1 33.3 22.8 46.4 9.5 11.7 44.6 48.3 64.1 47.6 35.6 56.6 23.5 10.7 46.5 20.8 3.9 23.7 17.3 16.6 0.6 5.5 5.4 53.3 22.5 44.6 6.7 27.2 105.6 0.0 12.3 19.0 32.1 16.0 30.4 84.4 25.6 22.9 17.2 8.9 15.9 15.8 21.6 24.3 34.8 13.2 7.1 1.4 0.9 2.5 2.1 1.3 1.7 1.2 1.9 1.8 1.7 1.2 1.9 0.0 2.1 1.5 1.3 0.8 1.4 8.3 15.8 25.2 12.6 9.5 10.6 16.0 16.7 13.8 10.1 14.8 11.3 8.2 25.6 34.8 16.0 13.1 1.0 1.4 35.0 1.2 10.8 1.6 0.4 17.8 8.6 18.1 9.2 8.4 15.6 24.8 37.3 1.9 7.8 9.4 6.7 3.5 20.2 21.4 3.6 38.8 9.2 6.0 6.0 15.8 11.5 32.3 6.5 5.0 39.9 20.3 6.7 20.8 32.5 22.4 19.6 26.7 8.3 7.2 27.8 3.6 20.6 5.7 7.1 9.2 20.1 23.6 10.0 30.0 7.9 17.6 3.3 30.1 5.7 9.5 7.6 19.7 2.4 15.2 8.7 9.4 6.8 2.6 14.1 14.5 38.2 23.0 5.2 STARD8 "ARHGAP38, KIAA0189" ENSG00000130052 "StAR related lipid transfer domain containing 8" Q92502 X 68647666-68725842 "Metabolic proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 27.9;Endothelial cells: 26.5;Hepatic stellate cells: 18.5;Kupffer cells: 13.7;Langerhans cells: 14.9;Macrophages: 13.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "classical monocyte: 1.6;intermediate monocyte: 3.2;myeloid DC: 3.4;non-classical monocyte: 4.7" "Group enriched" "Detected in many" 18 "dendritic cells: 3.4;monocytes: 4.7" "Cell line enhanced" "Detected in many" "HEL: 16.0;K-562: 20.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA060788 Uncertain NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA060788: AB_2684365" "unprognostic (2.00e-1)" "unprognostic (8.98e-2)" "unprognostic (1.56e-3)" "unprognostic (4.94e-3)" "unprognostic (1.73e-1)" "unprognostic (2.61e-2)" "unprognostic (2.77e-2)" "unprognostic (1.58e-1)" "unprognostic (1.71e-1)" "unprognostic (5.09e-3)" "unprognostic (9.72e-2)" "unprognostic (9.58e-2)" "unprognostic (5.19e-3)" "unprognostic (4.89e-3)" "unprognostic (9.46e-2)" "unprognostic (4.88e-2)" "unprognostic (1.07e-2)" 13.4 4.4 8.1 6.0 6.9 3.4 10.3 6.4 6.8 6.3 5.7 4.0 1.4 7.1 4.7 3.4 8.9 5.2 12.5 6.3 6.3 14.7 6.5 20.7 4.1 13.5 7.5 3.3 5.1 2.6 8.9 8.8 8.1 9.2 1.5 0.6 2.7 8.5 6.8 2.8 4.3 6.1 8.2 11.1 4.2 0.8 8.4 1.6 10.3 6.5 1.9 6.6 4.5 6.6 0.0 1.8 2.8 1.4 0.0 0.0 2.1 3.8 7.9 2.1 1.6 0.0 0.4 0.0 9.6 1.6 0.2 0.0 0.8 0.0 3.5 0.0 0.5 16.0 1.4 0.2 0.3 0.0 0.0 1.3 0.0 5.4 0.0 6.1 9.9 0.0 20.4 0.0 5.3 0.8 0.0 9.5 1.6 0.0 0.3 0.0 10.1 5.4 9.5 0.0 0.0 0.7 0.1 0.9 0.3 5.6 1.3 2.2 7.0 9.6 4.0 3.1 3.7 0.0 0.0 0.0 7.2 6.6 5.7 0.0 1.6 0.0 0.0 3.2 0.0 0.2 0.0 0.0 3.4 0.0 0.0 0.0 0.1 0.0 4.7 0.1 0.0 1.8 8.1 6.9 6.4 6.8 6.3 6.3 13.5 7.5 8.1 8.2 8.4 6.6 27.9 0.0 6.0 0.0 0.3 2.2 0.0 0.0 0.0 0.0 0.2 0.3 8.5 0.0 1.8 0.0 0.0 0.3 0.1 0.0 1.9 0.0 0.1 1.2 1.6 26.5 0.0 2.1 0.3 0.0 0.2 3.0 0.5 1.1 7.0 0.3 18.5 6.5 3.6 0.0 0.8 0.0 0.0 13.7 14.9 0.0 0.3 13.9 0.0 9.4 2.4 0.3 0.0 0.5 0.5 0.8 0.0 0.0 0.9 0.1 0.0 2.4 2.2 0.4 0.0 2.8 3.5 0.1 0.2 0.2 1.4 0.1 0.6 0.2 0.0 0.1 STIL "MCPH7, SIL" ENSG00000123473 "STIL centriolar assembly protein" Q15468 1 47250139-47314147 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.8;lymphoid tissue: 9.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 12.8;Glandular and luminal cells: 12.4;Spermatocytes: 17.8;Spermatogonia: 14.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA046543 Approved "Plasma membrane,Cytosol" NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "HPA046543: AB_2679692" "unprognostic (2.07e-1)" "unprognostic (6.29e-2)" "unprognostic (5.54e-3)" "unprognostic (2.67e-3)" "unprognostic (1.76e-1)" "unprognostic (1.56e-2)" "unprognostic (2.90e-5)" "unprognostic (7.35e-3)" "unprognostic (4.04e-3)" "unprognostic (1.41e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (5.81e-2)" "unprognostic (3.36e-14)" "unprognostic (5.76e-3)" "unprognostic (2.58e-1)" "unprognostic (1.64e-1)" "unprognostic (2.28e-1)" 1.0 0.5 0.8 3.0 0.8 10.8 2.9 0.7 1.2 1.1 0.2 4.1 2.9 1.4 1.4 2.5 0.9 1.4 0.6 0.8 0.6 0.7 1.0 0.9 4.9 0.7 0.6 0.8 0.7 0.9 0.4 1.9 0.8 1.3 5.6 1.2 1.7 0.5 0.6 3.1 2.7 1.4 0.4 1.4 1.8 6.6 0.8 9.9 0.9 0.7 5.7 1.1 1.0 1.0 33.7 17.4 24.7 22.1 1.8 3.8 15.7 29.3 14.0 32.0 33.2 18.5 16.1 39.4 13.3 14.4 32.7 21.4 29.4 15.3 33.7 29.6 12.9 44.5 20.9 16.6 0.8 35.7 21.5 1.6 2.1 27.2 17.5 3.8 21.5 29.5 31.7 35.9 24.1 14.3 35.6 10.9 30.0 18.6 14.2 23.0 40.3 19.0 9.0 20.0 22.0 13.2 31.4 22.2 14.6 29.6 14.5 20.6 12.2 29.6 29.9 21.2 40.0 11.9 26.4 38.1 13.8 27.0 28.0 0.3 0.1 0.2 0.2 0.0 0.0 0.4 0.2 0.2 0.1 0.2 0.0 0.1 0.3 0.7 0.0 0.3 0.3 0.1 0.8 0.8 0.7 1.2 0.8 0.6 0.7 0.6 0.8 0.4 0.8 1.0 1.6 3.2 0.5 2.0 2.4 0.9 0.6 2.0 1.2 1.1 2.8 3.0 0.5 0.0 2.3 0.0 4.2 2.5 1.6 5.4 0.0 1.6 1.6 7.8 3.2 2.2 1.8 12.8 5.1 0.4 4.4 1.6 3.1 12.4 2.5 8.2 1.4 0.5 2.9 0.0 3.9 6.1 0.0 2.4 1.2 1.1 0.3 2.7 0.0 0.0 3.0 0.8 1.0 2.0 4.8 1.9 1.8 0.7 10.2 1.1 1.4 0.4 7.6 0.6 0.0 1.7 2.0 17.8 14.4 5.3 2.4 0.8 3.3 2.6 5.5 1.4 STK17B DRAK2 ENSG00000081320 "Serine/threonine kinase 17b" O94768 2 196133583-196176503 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 376.2;lymphoid tissue: 113.3" "Cell type enhanced" "Detected in many" "B-cells: 229.3;dendritic cells: 267.7;granulocytes: 195.1;Langerhans cells: 201.3;Macrophages: 198.9;Plasma cells: 191.8;T-cells: 342.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 122.3;HMC-1: 118.9;Karpas-707: 111.6;U-698: 132.1" "Region enriched" "Detected in all" 5 "cerebellum: 63.4" "Low region specificity" "Detected in all" HPA034858 Enhanced Uncertain "Plasma membrane,Cytosol" NA Yes "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA034858: AB_10670981" "unprognostic (2.14e-1)" "unprognostic (2.45e-3)" "unprognostic (3.68e-2)" "unprognostic (3.61e-2)" "unprognostic (3.63e-2)" "unprognostic (7.43e-3)" "unprognostic (1.75e-1)" "unprognostic (7.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.14e-1)" "unprognostic (9.90e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.72e-8)" "unprognostic (1.88e-1)" "unprognostic (1.19e-2)" "unprognostic (2.64e-2)" "unprognostic (5.80e-2)" 28.2 8.9 2.1 67.0 2.9 376.2 21.5 3.7 5.3 24.2 3.3 19.1 27.8 5.4 1.8 11.9 5.8 20.4 4.6 4.1 3.3 6.5 8.5 23.6 113.3 3.1 2.0 2.2 12.7 2.1 3.0 16.7 3.2 10.5 17.5 0.4 17.0 5.7 2.4 11.2 40.1 16.8 2.2 56.9 20.1 9.5 4.0 60.9 7.2 3.5 111.1 24.4 5.2 2.9 11.0 7.5 11.2 4.2 47.7 18.1 12.4 25.7 38.4 27.7 28.5 22.8 3.9 122.3 23.1 14.8 7.3 7.4 4.7 11.1 33.4 21.8 12.7 11.6 9.1 2.2 14.2 47.0 118.9 23.1 10.9 34.3 17.7 39.2 11.5 28.5 9.1 111.6 69.4 5.9 61.6 106.0 6.3 19.9 17.2 10.1 67.5 37.4 16.3 25.6 4.2 4.2 6.6 6.4 5.4 17.2 4.3 24.3 14.0 26.8 13.1 19.3 14.7 45.5 78.9 132.1 20.2 15.9 12.1 165.1 74.3 163.1 43.7 81.3 55.4 49.2 77.0 52.8 53.0 58.6 98.6 82.4 236.7 40.8 113.1 37.7 73.8 89.3 2.1 2.9 3.7 5.3 4.1 3.3 3.1 2.0 3.2 2.2 4.0 2.9 23.3 89.8 74.0 48.3 229.3 59.9 27.1 15.1 10.8 0.9 28.9 15.2 2.6 12.8 42.5 11.0 0.0 7.9 267.7 54.0 3.9 6.6 6.8 15.3 14.1 11.3 3.0 68.8 3.4 2.8 24.0 27.2 38.2 26.5 195.1 47.4 5.3 2.4 26.1 0.0 3.1 13.9 18.3 151.1 201.3 3.6 5.6 198.9 58.7 11.2 158.0 0.6 118.4 17.6 0.7 10.9 41.6 4.5 191.8 34.3 80.7 2.5 26.9 0.3 6.6 49.7 19.7 41.1 26.3 16.4 63.4 5.1 342.5 22.6 13.2 53.8 SUN2 UNC84B ENSG00000100242 "Sad1 and UNC84 domain containing 2" Q9UH99 22 38734725-38794143 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 201.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001209 Supported Supported "Nuclear membrane" NA Yes "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear membrane" "HPA001209: AB_1080465" "unprognostic (9.76e-2)" "unprognostic (1.42e-1)" "unprognostic (8.32e-2)" "unprognostic (5.09e-2)" "unprognostic (1.36e-1)" "unprognostic (5.57e-2)" "unprognostic (1.94e-2)" "unprognostic (2.37e-2)" "unprognostic (3.14e-2)" "unprognostic (1.25e-3)" "unprognostic (8.15e-2)" "unprognostic (4.10e-2)" "unprognostic (1.06e-1)" "unprognostic (1.75e-1)" "unprognostic (1.31e-1)" "unprognostic (8.10e-2)" "unprognostic (2.33e-2)" 137.8 35.1 123.6 73.6 219.0 160.4 111.7 149.1 155.3 95.4 41.4 107.8 47.6 128.2 22.2 84.0 125.3 41.1 86.7 118.3 133.1 52.8 121.9 107.0 104.0 187.1 182.2 112.9 78.0 18.2 40.3 28.7 170.7 78.2 25.2 12.3 74.9 52.1 145.4 90.3 93.1 46.1 107.2 97.2 94.3 34.6 163.3 74.3 53.1 63.8 60.0 121.7 89.0 257.7 89.8 41.0 40.0 44.7 118.8 29.5 52.0 60.2 69.4 69.7 58.9 36.8 98.7 28.1 71.9 85.9 43.1 65.4 13.4 44.7 28.4 98.0 54.7 18.4 44.7 33.7 71.9 62.3 184.0 25.0 37.3 33.6 31.2 46.9 56.2 55.3 23.5 154.3 38.5 28.7 35.0 53.9 3.9 63.0 26.2 57.6 55.8 85.7 17.4 43.1 35.3 13.2 67.0 73.7 35.1 18.5 49.5 115.3 95.2 50.6 43.3 44.9 79.5 113.1 38.2 30.4 93.8 74.2 86.6 29.0 13.7 18.6 42.3 15.6 27.5 10.8 27.0 34.9 10.7 10.1 27.6 33.6 13.9 24.8 26.9 6.7 19.9 24.8 123.6 219.0 149.1 155.3 118.3 133.1 187.1 182.2 170.7 107.2 163.3 257.7 55.5 22.4 22.9 20.2 57.0 18.1 28.4 15.1 24.5 9.9 36.5 39.0 6.2 40.0 17.8 33.1 8.4 16.9 141.8 65.6 3.9 34.9 1.8 11.6 15.8 37.4 18.6 31.8 12.5 47.6 65.9 34.0 42.8 32.9 25.4 41.5 52.1 109.6 25.0 21.9 7.7 30.1 8.2 42.4 21.4 4.4 61.2 41.8 17.8 16.9 25.5 21.4 201.8 7.1 132.9 60.0 41.8 65.5 44.7 22.0 42.2 18.9 5.7 13.0 52.6 100.7 37.0 3.8 1.1 32.1 17.2 14.8 133.4 10.9 21.4 21.4 SURF4 "ERV29, FLJ22993, MGC102753" ENSG00000148248 "Surfeit 4" O15260 9 133361450-133376166 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 325.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064613 Approved Supported "Nuclear membrane,Endoplasmic reticulum,Golgi apparatus,Cytosol" NA Yes 65000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear membrane, Endoplasmic reticulum, Golgi apparatus" Cytosol "HPA064613: AB_2685299" "prognostic unfavorable (5.85e-4)" "unprognostic (1.38e-2)" "unprognostic (1.92e-1)" "unprognostic (2.04e-2)" "unprognostic (3.40e-2)" "prognostic unfavorable (1.47e-5)" "prognostic unfavorable (8.11e-4)" "unprognostic (1.10e-3)" "unprognostic (3.13e-2)" "unprognostic (1.90e-1)" "unprognostic (5.30e-3)" "unprognostic (1.23e-1)" "unprognostic (9.76e-3)" "unprognostic (7.58e-3)" "unprognostic (1.25e-1)" "unprognostic (2.29e-1)" "unprognostic (4.29e-3)" 97.0 106.4 20.3 38.8 22.5 66.5 76.5 22.1 23.4 70.5 27.9 72.1 79.2 78.5 40.6 77.6 71.1 39.0 74.1 21.5 22.3 67.1 223.8 84.2 29.6 23.6 22.2 61.0 150.4 35.4 88.6 55.4 22.2 69.2 37.9 14.0 86.4 39.5 60.1 63.2 82.2 43.4 22.9 59.6 88.5 49.4 25.8 27.8 68.2 23.3 31.4 62.7 59.4 25.9 59.8 96.4 65.3 90.3 134.8 140.2 127.4 184.1 178.4 127.0 124.7 145.9 84.8 41.1 70.6 254.2 122.9 152.7 75.7 94.4 97.0 86.5 46.3 72.1 87.1 156.5 156.2 124.8 94.1 150.4 85.8 109.3 120.2 101.6 118.6 62.9 89.0 109.8 164.5 131.8 60.1 115.4 72.7 162.8 96.2 41.2 89.9 156.5 100.4 56.3 53.8 65.5 136.4 100.4 95.2 61.5 106.6 75.8 127.5 179.4 64.5 137.3 119.6 56.1 86.4 46.4 166.7 66.6 137.5 43.9 40.8 36.2 51.9 32.8 56.9 15.1 36.3 48.4 32.9 12.1 22.0 34.6 28.4 29.4 31.7 38.9 46.9 68.8 20.3 22.5 22.1 23.4 21.5 22.3 23.6 22.2 22.2 22.9 25.8 25.9 53.5 44.8 48.1 18.9 43.0 60.8 65.8 72.5 46.1 21.9 55.5 43.2 42.6 31.5 47.5 35.0 39.6 167.9 80.4 106.9 19.6 95.7 38.6 28.6 72.8 54.8 75.2 31.1 23.2 118.1 254.4 84.8 78.5 67.7 24.7 49.5 47.5 207.3 85.9 33.7 15.6 107.9 30.5 52.3 50.5 19.7 68.3 50.8 40.9 17.8 53.7 53.3 52.5 22.6 23.8 115.1 65.5 53.0 114.8 106.8 151.3 48.5 23.2 26.9 78.9 51.9 80.6 84.4 47.3 46.1 62.4 325.2 90.5 81.8 81.2 84.2 SUV39H1 "KMT1A, SUV39H" ENSG00000101945 "Suppressor of variegation 3-9 homolog 1" O43463 X 48695554-48709016 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Differentiation, Host-virus interaction, rRNA processing, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (4.92e-2)" "prognostic favorable (8.93e-5)" "unprognostic (9.51e-2)" "unprognostic (4.18e-2)" "unprognostic (1.75e-1)" "unprognostic (1.66e-2)" "unprognostic (1.36e-2)" "unprognostic (1.94e-1)" "unprognostic (1.03e-1)" "unprognostic (3.59e-2)" "unprognostic (1.13e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (1.91e-7)" "unprognostic (2.29e-3)" "unprognostic (6.47e-3)" "unprognostic (2.01e-1)" "unprognostic (5.67e-2)" 4.0 2.2 4.7 4.2 4.4 13.7 3.5 4.9 5.1 2.9 2.0 3.4 3.1 3.2 12.5 5.0 3.3 1.7 3.6 4.3 5.1 2.6 6.6 2.7 7.5 5.2 5.6 3.8 2.9 2.3 3.0 3.3 4.8 3.0 3.2 3.3 2.6 3.0 4.9 4.4 4.2 2.6 3.9 6.0 3.6 4.9 5.0 9.7 2.6 3.8 7.0 3.4 2.4 4.3 28.7 34.3 13.3 14.0 3.4 4.0 27.0 13.5 10.2 25.8 21.0 21.0 18.7 31.4 8.0 9.9 26.1 19.8 33.0 19.3 15.4 24.2 33.8 12.3 31.8 17.4 2.0 30.7 6.6 3.6 3.7 22.8 11.6 4.2 18.6 20.2 31.9 21.6 14.2 33.1 26.8 32.0 15.7 14.0 32.8 19.3 24.5 33.1 8.6 15.7 17.4 11.4 18.3 17.4 9.8 14.8 26.0 25.5 10.0 15.8 27.0 22.1 23.3 14.6 23.9 26.4 11.8 43.6 17.7 4.9 2.8 6.8 8.5 4.0 6.2 4.6 5.5 9.1 2.2 5.4 6.8 6.6 2.0 10.6 6.5 2.6 11.0 6.5 4.7 4.4 4.9 5.1 4.3 5.1 5.2 5.6 4.8 3.9 5.0 4.3 1.2 6.4 0.0 0.3 3.5 1.8 0.9 2.0 2.8 5.3 2.2 2.5 2.5 2.8 1.3 1.8 0.0 6.5 6.6 2.1 3.9 2.9 0.2 1.3 0.9 1.7 3.0 6.9 0.7 2.9 28.3 1.9 3.1 1.0 1.3 2.9 1.8 6.7 5.2 0.0 1.0 2.6 0.0 2.9 1.6 0.2 1.2 2.4 5.4 1.0 3.0 0.9 6.2 1.0 0.8 2.3 1.7 1.5 7.1 0.6 1.6 2.4 2.6 3.8 0.0 1.8 2.5 3.7 0.8 2.5 1.1 6.2 3.6 1.7 3.2 0.6 SYNE2 "DKFZP434H2235, KIAA1011, Nesp2, Nesprin-2, NUA, NUANCE, SYNE-2" ENSG00000054654 "Spectrin repeat containing nuclear envelope protein 2" Q8WXH0 14 63761899-64226433 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Actin-binding "Disease variant, Emery-Dreifuss muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 198.5" "Cell type enhanced" "Detected in all" "Granulosa cells: 454.6;Rod photoreceptor cells: 568.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 73.8" "Group enriched" "Detected in many" 11 "granulocytes: 73.8;T-cells: 38.5" "Cell line enhanced" "Detected in many" "Daudi: 48.8;SiHa: 29.8;U-698: 27.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003435, HPA050204" Enhanced Approved "Nuclear membrane,Intermediate filaments" No Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" "Nuclear membrane, Intermediate filaments" "HPA003435: AB_1080162, HPA050204: AB_2681051" "unprognostic (1.93e-2)" "unprognostic (3.72e-2)" "unprognostic (1.91e-1)" "unprognostic (2.33e-1)" "unprognostic (2.64e-1)" "unprognostic (1.97e-3)" "unprognostic (9.04e-2)" "unprognostic (2.58e-3)" "unprognostic (1.99e-2)" "unprognostic (2.41e-2)" "unprognostic (1.25e-2)" "unprognostic (2.24e-1)" "prognostic favorable (3.56e-9)" "unprognostic (5.05e-3)" "unprognostic (3.14e-1)" "unprognostic (1.51e-2)" "unprognostic (4.80e-2)" 30.1 6.0 8.8 3.4 9.2 7.9 28.0 21.1 8.7 15.4 89.5 13.3 4.5 18.1 9.9 24.3 14.3 5.5 58.3 9.6 7.6 29.0 19.5 18.4 8.5 7.7 9.6 35.9 37.7 66.6 16.7 9.9 7.5 11.5 4.4 24.8 16.1 3.7 198.5 39.7 11.4 4.6 7.0 10.0 12.4 13.1 11.4 5.5 24.4 96.7 6.1 13.6 19.0 6.9 23.2 8.7 11.0 3.5 11.3 3.2 12.3 1.3 1.6 2.7 4.2 2.8 3.3 48.8 2.3 1.7 2.6 11.0 6.2 3.5 3.2 8.9 3.5 0.4 7.9 0.7 3.0 1.0 0.3 4.4 15.1 3.4 2.2 2.6 7.0 7.5 0.4 4.8 1.8 11.2 6.2 0.3 3.4 5.4 3.3 6.9 14.5 1.8 20.0 13.6 9.9 8.2 29.8 3.8 7.0 5.5 5.0 0.3 7.3 4.2 7.5 1.5 4.5 4.9 3.5 27.5 1.8 0.0 5.7 0.5 0.1 73.8 38.5 0.3 27.6 5.2 24.3 28.0 0.0 5.3 11.8 18.5 30.1 3.9 0.3 1.2 30.1 3.4 8.8 9.2 21.1 8.7 9.6 7.6 7.7 9.6 7.5 7.0 11.4 6.9 414.4 307.7 140.1 8.5 44.9 111.3 138.9 46.4 174.2 27.4 70.3 59.1 261.4 105.8 184.5 202.3 183.5 168.8 226.8 51.0 19.6 108.2 9.4 249.9 71.2 238.8 46.2 10.5 9.5 55.4 65.7 59.6 126.9 365.2 25.9 454.6 73.5 33.3 17.7 6.7 13.9 60.9 59.0 5.7 13.2 14.3 100.9 12.8 48.0 128.4 8.9 107.2 300.7 33.2 6.6 71.7 27.9 53.4 180.3 65.0 35.9 72.2 196.1 568.7 111.7 73.5 167.0 13.0 17.0 104.6 87.5 224.0 222.1 69.5 80.6 80.6 SYTL3 "exophilin-6, SLP3" ENSG00000164674 "Synaptotagmin like 3" Q4VX76 6 158650014-158764876 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 334.2;granulocytes: 135.4;NK-cells: 132.8;Plasma cells: 135.2;T-cells: 230.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 232.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 232.0" "Cell line enhanced" "Detected in many" "HMC-1: 23.9;U-138 MG: 18.9;U-2 OS: 19.1;U-266/70: 28.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030584, HPA030585, HPA030586" Approved Approved "Nucleoli fibrillar center,Vesicles" NA Yes "Cluster 38: Basophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoli fibrillar center, Vesicles" "HPA030584: AB_10600196, HPA030585: AB_10601239, HPA030586: AB_10601226" "unprognostic (3.56e-3)" "prognostic favorable (8.84e-5)" "unprognostic (6.37e-2)" "unprognostic (1.96e-3)" "unprognostic (3.88e-2)" "unprognostic (1.42e-1)" "unprognostic (7.76e-2)" "unprognostic (5.45e-3)" "unprognostic (9.33e-3)" "unprognostic (1.75e-1)" "unprognostic (3.07e-1)" "unprognostic (5.63e-2)" "unprognostic (8.58e-3)" "unprognostic (1.55e-1)" "unprognostic (6.28e-2)" "unprognostic (2.80e-2)" "unprognostic (1.83e-1)" 5.5 1.8 1.5 7.5 1.7 13.9 4.3 2.2 1.6 6.0 23.9 4.2 3.8 3.5 6.4 4.0 14.4 4.8 7.1 2.3 2.7 5.3 2.5 16.8 8.4 3.8 2.9 2.8 1.5 1.8 2.1 1.6 3.4 5.4 2.4 0.4 15.3 5.8 14.9 3.3 9.9 2.8 2.9 19.8 7.1 3.8 2.9 17.4 25.2 8.2 6.0 5.0 3.6 4.6 7.1 1.0 0.1 0.5 0.9 0.9 0.4 3.1 2.0 0.8 2.1 0.6 5.8 0.1 0.5 5.3 2.6 0.8 0.1 0.9 2.9 15.1 0.4 5.8 0.2 0.0 1.7 1.7 23.9 3.1 2.1 6.1 1.0 2.6 1.4 1.1 0.3 5.6 6.8 0.3 0.1 2.0 0.1 1.3 1.0 0.0 5.6 0.7 2.8 0.4 15.6 1.2 1.0 9.7 0.8 0.3 2.0 0.3 8.8 18.9 19.1 0.5 0.6 28.5 7.1 0.6 12.0 8.3 0.6 232.0 16.0 0.8 37.3 3.3 22.0 1.0 14.7 25.3 4.6 0.3 15.7 19.3 35.5 43.1 1.4 1.3 16.4 18.9 1.5 1.7 2.2 1.6 2.3 2.7 3.8 2.9 3.4 2.9 2.9 4.6 2.8 16.0 13.1 2.3 23.5 4.6 2.9 4.4 1.8 0.2 4.4 3.7 4.1 1.5 15.9 14.7 2.1 1.3 334.2 1.0 5.9 0.8 10.8 51.0 3.0 4.2 0.0 4.4 3.4 0.6 0.5 4.8 17.3 37.4 135.4 0.4 3.9 1.9 4.2 0.0 4.8 1.8 4.1 11.5 20.3 18.1 0.0 26.6 10.6 28.1 17.6 0.1 132.8 2.0 2.5 0.6 0.1 0.7 135.2 1.8 2.0 1.9 51.5 0.5 0.0 2.3 2.4 2.1 8.4 2.6 4.4 1.9 230.2 0.9 1.3 3.1 SYTL4 ENSG00000102362 "Synaptotagmin like 4" Q96C24 X 100674491-100732123 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 68.3" "Cell type enhanced" "Detected in many" "Granulosa cells: 58.1;Leydig cells: 72.7;Sertoli cells: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.7" "Lineage enriched" "Detected in single" 10 "granulocytes: 1.7" "Cell line enhanced" "Detected in many" "HAP1: 29.5;HMC-1: 60.0;RT4: 40.8;TIME: 34.9" "Region enriched" "Detected in many" 5 "hypothalamus: 30.1" "Low region specificity" "Detected in all" "HPA001475, HPA001589, HPA075138" Approved Approved Vesicles NA Yes 3300000 "Cluster 1: Neutrophils - Mixed function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA001475: AB_1080172, HPA001589: AB_1080174, HPA075138: " "unprognostic (7.82e-3)" "unprognostic (1.52e-1)" "unprognostic (3.43e-2)" "unprognostic (6.16e-2)" "unprognostic (1.04e-1)" "unprognostic (1.14e-1)" "unprognostic (5.78e-2)" "unprognostic (1.32e-1)" "unprognostic (3.35e-2)" "unprognostic (2.81e-1)" "unprognostic (1.07e-3)" "unprognostic (5.62e-2)" "prognostic unfavorable (2.09e-4)" "unprognostic (1.30e-1)" "unprognostic (1.56e-1)" "unprognostic (1.67e-1)" "unprognostic (1.60e-2)" 6.9 4.1 6.9 2.2 13.2 2.3 6.0 4.5 5.1 21.7 14.1 9.8 2.1 43.1 3.1 3.9 17.8 4.0 3.2 5.2 13.1 5.6 10.5 4.7 0.7 8.4 9.3 68.3 8.3 1.2 18.8 3.6 7.4 12.7 9.7 1.3 6.1 7.2 2.3 2.0 4.9 32.7 6.1 3.3 7.4 6.8 18.0 0.6 8.8 4.9 1.7 6.1 10.2 7.9 0.3 6.0 1.6 0.0 8.5 4.8 0.1 7.7 4.9 8.0 14.3 0.7 7.6 0.0 2.0 5.4 6.9 6.8 29.5 2.3 8.4 0.0 2.6 0.1 10.8 0.4 2.1 0.0 60.0 1.7 0.5 7.3 0.4 3.1 20.5 0.0 3.0 0.0 3.8 2.0 0.1 0.0 1.2 21.2 0.0 0.0 2.4 0.0 7.0 40.8 14.5 0.6 3.1 11.5 1.7 3.0 7.1 0.6 34.9 4.2 8.8 20.9 1.9 0.1 0.0 0.1 5.2 0.0 4.8 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 1.7 0.1 0.0 0.0 0.0 0.8 6.9 13.2 4.5 5.1 5.2 13.1 8.4 9.3 7.4 6.1 18.0 7.9 15.6 28.9 1.7 41.8 0.5 0.1 7.7 3.1 1.2 0.2 19.0 6.6 3.8 18.6 8.0 3.7 0.0 0.4 0.7 29.1 3.9 8.9 1.6 4.3 25.8 13.5 0.0 5.0 0.5 2.3 0.4 20.0 26.5 6.2 3.8 58.1 11.4 38.6 1.3 0.0 1.0 26.9 8.2 1.6 1.9 3.8 72.7 7.2 3.6 8.4 0.5 5.4 0.0 10.6 0.2 7.2 27.1 41.8 0.5 11.9 5.8 2.6 8.1 0.6 52.6 38.1 11.8 2.6 4.4 2.6 0.9 0.0 0.9 18.0 9.6 13.8 TACC3 "ERIC-1, ERIC1, maskin, Tacc4" ENSG00000013810 "Transforming acidic coiled-coil containing protein 3" Q9Y6A5 4 1712891-1745171 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 58.9;lymphoid tissue: 52.4;testis: 50.6" "Cell type enhanced" "Detected in many" "Early spermatids: 70.4;Hofbauer cells: 43.9;Late spermatids: 69.9;Spermatocytes: 94.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005781, HPA006050, CAB010111, HPA022039" Enhanced Enhanced "Vesicles,Mitotic spindle,Centriolar satellite,Cytosol" Yes Yes 11000 "Cluster 5: Granulocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Mitotic spindle, Centriolar satellite, Cytosol" Vesicles "CAB010111: AB_628323, HPA005781: AB_1857724, HPA006050: AB_2667505, HPA022039: AB_1857725" "unprognostic (2.95e-1)" "unprognostic (1.18e-1)" "unprognostic (7.71e-2)" "unprognostic (4.35e-2)" "unprognostic (6.58e-2)" "unprognostic (1.84e-2)" "prognostic unfavorable (3.30e-4)" "unprognostic (1.10e-3)" "unprognostic (4.61e-2)" "unprognostic (9.12e-2)" "unprognostic (2.91e-2)" "unprognostic (2.26e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.66e-2)" "unprognostic (2.09e-1)" "unprognostic (4.44e-3)" "unprognostic (9.75e-2)" 5.3 3.9 4.2 24.9 4.3 58.9 3.5 5.2 5.3 3.6 5.2 10.3 6.6 3.3 4.8 14.9 2.8 4.2 3.3 4.5 4.4 2.7 3.5 6.5 43.2 4.8 5.3 2.2 1.4 2.3 2.6 8.7 4.8 2.4 10.6 1.9 3.9 2.5 2.0 6.4 12.9 6.4 4.2 22.1 6.4 50.6 5.1 52.4 2.8 3.4 39.3 5.0 5.4 4.7 106.7 88.7 129.5 72.2 6.7 15.2 72.9 114.6 62.1 135.4 87.6 93.5 122.8 133.8 48.0 65.4 149.9 71.4 142.5 86.8 131.1 59.8 77.0 113.8 67.2 85.8 5.9 146.6 85.5 5.2 5.7 85.6 46.0 26.0 102.2 110.3 106.3 90.8 123.8 87.1 207.5 204.0 139.3 89.2 111.6 139.1 90.5 55.0 73.8 125.5 99.8 62.8 70.1 42.3 33.1 95.2 83.3 90.5 56.4 75.4 90.0 65.4 176.7 69.5 102.5 207.1 43.2 141.1 109.1 45.5 30.0 37.9 8.5 12.5 11.1 7.8 16.5 11.5 15.3 10.8 28.3 13.1 91.8 12.2 9.6 8.3 42.5 32.5 4.2 4.3 5.2 5.3 4.5 4.4 4.8 5.3 4.8 4.2 5.1 4.7 6.0 0.0 6.7 2.0 16.5 2.2 1.2 3.2 1.2 1.7 2.4 3.0 2.6 2.8 3.4 9.2 8.4 19.5 6.4 11.2 0.0 2.2 70.4 4.2 2.8 5.2 1.2 37.2 2.3 0.7 20.4 6.0 12.8 4.3 5.1 24.5 8.9 5.1 43.9 5.0 3.2 9.5 4.1 23.2 10.8 69.9 2.8 34.1 0.0 4.7 24.4 1.4 6.2 0.5 0.8 2.9 4.2 2.6 18.0 1.3 2.6 2.8 0.9 2.7 6.6 2.0 4.8 94.3 37.7 12.8 1.4 4.0 23.2 2.2 16.1 2.7 TBC1D2 "Armus, PARIS1, TBC1D2A" ENSG00000095383 "TBC1 domain family member 2" Q9BYX2 9 98199011-98255649 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Oligodendrocytes: 64.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 27.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 77.0;HaCaT: 98.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA030871, HPA076521" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Plasma membrane, Cytosol" "HPA030871: AB_10670046, HPA076521: " "unprognostic (2.32e-2)" "unprognostic (1.11e-1)" "unprognostic (1.06e-2)" "unprognostic (6.36e-3)" "unprognostic (2.02e-2)" "prognostic unfavorable (2.77e-4)" "unprognostic (1.86e-1)" "unprognostic (2.11e-1)" "unprognostic (1.74e-1)" "unprognostic (9.21e-3)" "unprognostic (6.40e-3)" "unprognostic (2.30e-1)" "unprognostic (6.07e-2)" "unprognostic (4.32e-1)" "prognostic unfavorable (5.62e-4)" "unprognostic (1.30e-2)" "unprognostic (4.30e-1)" 8.8 5.3 11.1 5.7 16.0 13.1 7.8 12.3 26.0 10.8 8.5 8.6 12.6 4.4 1.5 37.4 5.5 4.0 3.7 10.6 12.9 6.4 19.8 32.0 3.8 14.9 14.9 2.9 3.0 3.5 4.4 7.2 16.4 12.0 4.4 3.4 14.7 6.1 4.3 24.3 10.1 2.8 11.4 9.4 7.0 3.4 23.3 3.0 8.1 1.4 4.9 11.7 17.3 23.9 77.0 10.8 0.5 2.5 8.2 15.9 24.3 33.2 18.4 23.8 19.6 6.9 32.8 1.3 24.7 19.6 5.2 98.1 0.7 36.8 8.3 2.6 1.4 0.7 38.0 5.4 37.6 1.7 2.9 21.7 59.8 23.6 58.7 41.5 8.6 2.1 2.4 1.0 19.0 9.9 0.4 4.6 1.6 7.4 6.2 1.2 4.8 0.2 36.0 46.7 0.9 1.4 11.3 24.4 3.4 1.7 8.1 2.6 51.7 28.8 8.6 4.8 13.6 1.6 1.5 0.6 29.0 2.9 3.2 2.1 27.5 8.4 2.5 15.3 1.8 1.2 3.8 2.2 10.0 0.8 1.6 1.9 11.9 1.2 12.3 1.3 5.5 10.8 11.1 16.0 12.3 26.0 10.6 12.9 14.9 14.9 16.4 11.4 23.3 23.9 2.9 57.7 12.5 5.2 2.4 8.3 18.5 30.4 21.6 3.3 2.7 5.6 0.7 4.3 23.3 3.7 0.0 21.5 0.9 16.2 3.9 3.3 1.8 4.6 3.7 5.0 7.7 0.4 4.6 3.2 10.9 2.4 6.1 10.3 0.0 0.6 1.1 6.1 32.0 1.7 5.4 12.6 18.3 16.2 1.8 1.2 1.8 18.3 3.6 4.7 7.5 4.4 3.1 12.1 64.9 14.4 10.7 0.7 1.7 9.2 16.4 3.2 10.8 2.4 0.0 1.8 3.4 2.1 3.0 29.8 10.9 17.4 2.4 0.7 5.7 17.1 TBKBP1 "KIAA0775, ProSAPiP2" ENSG00000198933 "TBK1 binding protein 1" A7MCY6 17 47694081-47712050 "Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 62.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062347, HPA064856" Approved Approved Nucleoplasm NA Yes "Cluster 1: Neutrophils - Mixed function" "Cluster 47: Non-specific - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA062347: AB_2684744, HPA064856: AB_2685371" "unprognostic (2.14e-3)" "unprognostic (1.15e-1)" "unprognostic (2.42e-2)" "unprognostic (1.92e-2)" "unprognostic (2.39e-1)" "unprognostic (3.09e-2)" "unprognostic (3.72e-1)" "unprognostic (1.05e-1)" "unprognostic (1.51e-1)" "unprognostic (3.24e-1)" "prognostic favorable (8.14e-6)" "unprognostic (5.83e-2)" "unprognostic (1.14e-1)" "unprognostic (3.03e-1)" "unprognostic (4.22e-1)" "unprognostic (1.56e-1)" "prognostic favorable (1.59e-5)" 13.9 10.9 25.2 8.5 22.3 6.7 12.0 11.4 29.9 17.1 6.3 15.3 3.1 14.0 2.1 11.3 14.2 8.1 16.4 27.3 19.3 12.9 3.4 12.3 6.0 18.4 19.8 21.4 9.6 10.1 11.6 9.5 18.2 13.4 2.2 10.4 15.9 9.3 35.5 7.4 7.8 7.9 11.6 18.4 10.5 14.2 24.4 3.2 11.7 22.3 3.4 14.9 12.3 18.5 0.5 10.0 18.3 19.4 9.2 9.3 11.9 10.1 10.6 4.9 5.8 62.8 1.5 0.3 9.9 12.6 8.7 1.1 14.4 2.6 2.9 12.3 32.6 26.8 9.8 10.7 21.2 5.1 5.7 18.8 6.5 1.1 1.8 15.2 17.4 7.3 23.5 0.0 2.8 2.8 3.3 25.2 25.5 0.5 7.0 12.0 5.7 10.5 6.1 0.8 15.8 29.5 4.8 1.2 5.2 17.2 11.0 11.4 20.2 15.1 17.8 18.4 1.2 6.8 0.7 12.4 8.8 9.6 3.9 0.0 0.2 0.4 1.0 0.1 0.5 0.0 0.3 0.8 0.2 0.2 0.1 0.3 2.2 0.9 0.0 0.2 0.2 0.1 25.2 22.3 11.4 29.9 27.3 19.3 18.4 19.8 18.2 11.6 24.4 18.5 15.5 0.0 1.1 13.4 2.4 4.0 3.2 0.9 1.8 13.7 2.8 3.4 3.7 1.5 1.1 3.7 2.1 0.1 6.3 0.0 1.9 1.1 6.9 0.7 3.5 9.7 5.3 3.2 6.9 1.8 0.2 3.9 2.6 1.2 0.0 4.2 10.4 1.1 3.2 28.6 12.1 0.5 4.1 2.9 4.0 6.6 8.7 2.2 1.8 5.6 1.1 4.7 5.2 9.5 1.2 0.9 0.0 8.6 2.2 5.5 0.0 5.0 0.8 3.7 0.0 1.5 2.7 3.8 5.3 2.0 3.0 0.3 3.9 1.3 0.1 2.2 TCF19 SC1 ENSG00000137310 "Transcription factor 19" Q9Y242 6 31158547-31167159 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 37.0;Glandular and luminal cells: 17.6;Plasma cells: 21.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 82.8;GAMG: 47.0;HEK 293: 43.3;JURKAT: 40.9;Karpas-707: 39.2;SCLC-21H: 48.5;U-138 MG: 49.0" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA065994 Approved Nucleoplasm,Nucleoli NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "HPA065994: " "unprognostic (1.41e-2)" "unprognostic (4.92e-2)" "unprognostic (4.00e-2)" "unprognostic (5.16e-3)" "unprognostic (1.99e-2)" "unprognostic (6.04e-2)" "prognostic unfavorable (5.66e-4)" "unprognostic (7.04e-2)" "unprognostic (1.35e-2)" "unprognostic (5.92e-2)" "unprognostic (1.74e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (3.54e-10)" "unprognostic (3.11e-2)" "unprognostic (1.05e-1)" "unprognostic (1.36e-2)" "unprognostic (1.21e-1)" 4.6 1.7 0.3 2.6 0.4 1.0 4.3 0.7 0.4 6.9 0.2 5.8 4.4 4.2 2.1 12.5 3.8 0.4 3.7 0.3 0.3 4.1 2.0 4.4 10.0 0.5 0.4 4.8 3.2 0.0 1.3 0.3 0.5 5.1 1.7 0.6 4.7 0.8 2.7 8.9 7.2 1.1 0.3 9.5 5.5 1.9 0.7 0.0 2.4 0.1 1.7 5.2 8.1 0.3 82.8 0.7 0.7 0.1 5.4 7.0 0.7 0.5 0.0 0.1 0.1 5.3 0.1 0.1 17.7 20.1 47.0 0.1 0.0 30.3 0.0 0.5 43.3 7.3 5.1 2.0 0.0 0.2 21.1 2.9 0.0 2.3 0.0 4.4 17.9 40.9 0.1 39.2 8.1 0.3 1.2 13.2 0.1 0.0 0.0 1.1 4.8 0.7 7.1 0.3 48.5 0.5 0.4 0.1 0.5 6.5 0.1 6.0 0.0 49.0 0.2 0.4 0.4 12.5 15.0 24.8 0.1 0.3 0.3 0.0 0.1 0.0 0.2 0.0 1.3 0.5 0.6 1.1 0.3 0.5 0.8 0.2 0.1 0.4 0.0 0.0 1.0 0.5 0.3 0.4 0.7 0.4 0.3 0.3 0.5 0.4 0.5 0.3 0.7 0.3 2.8 3.2 0.6 0.7 6.7 5.1 3.1 2.5 8.6 3.0 2.8 2.9 1.2 0.0 2.5 3.7 0.0 2.9 3.9 1.8 7.9 1.3 0.3 4.7 2.0 4.7 1.2 37.0 0.1 1.8 9.6 5.6 5.6 17.6 1.3 7.0 1.8 0.6 8.9 1.7 0.2 3.9 2.0 2.9 5.4 0.7 5.0 4.8 12.4 0.0 6.0 4.2 8.2 0.0 0.2 1.1 0.9 6.4 21.1 1.3 1.6 0.4 0.2 0.5 0.0 3.5 5.3 0.7 11.1 9.6 3.8 0.4 7.6 2.0 8.8 2.9 TCP11L1 FLJ11336 ENSG00000176148 "T-complex 11 like 1" Q9NUJ3 11 33039417-33105943 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 29.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005769 Approved Approved "Golgi apparatus,Cytosol" NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 10: Brain - Neuronal signaling" "Cluster 20: HeLa - Mitochondria" "Cluster 3: Monocytes - Immune response regulation" Cytosol "Golgi apparatus" "HPA005769: AB_2202398" "unprognostic (5.22e-2)" "unprognostic (1.40e-1)" "unprognostic (3.51e-2)" "unprognostic (1.20e-1)" "unprognostic (1.77e-1)" "unprognostic (3.73e-2)" "unprognostic (4.16e-2)" "unprognostic (1.83e-2)" "unprognostic (6.99e-2)" "unprognostic (9.10e-2)" "unprognostic (1.42e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.39e-5)" "unprognostic (1.36e-1)" "unprognostic (2.01e-1)" "unprognostic (1.39e-1)" "unprognostic (9.50e-3)" 6.3 5.0 5.6 5.5 7.9 7.4 4.5 0.7 7.3 4.8 0.0 6.9 6.1 5.0 3.3 4.9 4.0 8.1 4.7 9.6 7.4 5.9 4.0 4.6 4.9 4.9 8.9 5.3 5.7 4.0 5.0 7.0 8.3 5.0 7.2 6.0 4.9 7.0 3.0 5.4 8.9 8.7 1.0 5.4 4.2 5.6 3.1 7.6 3.2 4.1 5.7 5.8 4.5 7.5 11.9 21.3 10.7 10.2 18.3 20.3 7.2 16.9 14.4 12.8 17.3 11.0 5.6 12.3 4.6 33.1 19.0 18.7 14.5 13.2 18.2 16.1 13.0 8.3 23.1 8.1 12.0 8.2 10.8 16.4 16.2 13.2 25.0 14.6 12.8 17.4 5.2 14.3 32.4 17.6 8.1 3.2 8.0 8.8 8.2 9.4 22.4 2.2 11.6 4.6 9.1 18.3 43.3 27.5 7.9 13.5 7.0 3.4 20.0 22.7 32.5 25.7 18.1 17.5 19.7 13.9 16.5 4.0 18.1 18.6 6.1 8.8 3.4 3.9 3.4 2.1 1.8 3.8 5.9 2.8 1.8 2.4 3.6 4.8 1.1 11.1 5.9 3.5 5.6 7.9 0.7 7.3 9.6 7.4 4.9 8.9 8.3 1.0 3.1 7.5 4.9 9.6 1.1 12.7 5.0 2.3 10.7 4.2 12.0 5.6 1.7 2.0 3.1 2.8 1.8 0.0 4.2 3.8 4.6 3.5 1.9 4.6 11.6 1.8 4.4 4.5 1.8 2.1 22.5 4.0 19.2 6.3 3.1 2.3 4.5 2.4 4.2 1.6 6.8 8.4 23.7 1.2 2.0 5.7 5.2 6.3 1.8 6.9 0.0 18.7 20.2 1.6 8.2 23.1 29.6 5.7 1.6 2.6 11.6 8.9 13.3 5.0 0.7 5.7 0.0 7.0 6.4 10.4 5.4 6.1 2.6 4.7 6.7 2.8 1.4 3.9 TGFB2 ENSG00000092969 "Transforming growth factor beta 2" P61812 1 218345336-218444619 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Growth factor, Mitogen" "Aortic aneurysm, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Astrocytes: 119.1;Muller glia cells: 87.1" "Cancer enhanced" "Detected in all" "glioma: 11.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 59.6;hTERT-RPE1: 155.6;U-2 OS: 58.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006134 Approved Vesicles "Secreted to blood" NA Yes 4890000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "HPA006134: " "unprognostic (7.24e-2)" "unprognostic (7.23e-2)" "unprognostic (6.32e-2)" "unprognostic (2.45e-1)" "unprognostic (1.79e-1)" "unprognostic (3.86e-1)" "unprognostic (3.44e-2)" "unprognostic (1.99e-1)" "unprognostic (2.19e-2)" "unprognostic (2.35e-1)" "unprognostic (1.32e-2)" "unprognostic (1.31e-1)" "unprognostic (2.43e-2)" "unprognostic (2.64e-3)" "unprognostic (1.23e-1)" "unprognostic (4.90e-2)" "unprognostic (6.04e-2)" 1.5 1.2 8.2 1.1 11.6 0.1 4.0 9.2 14.9 7.1 7.1 2.4 0.6 6.5 4.5 1.8 3.9 2.0 6.4 11.5 11.1 1.4 0.6 7.8 0.6 18.5 12.7 4.6 1.8 1.1 2.1 12.9 10.7 17.0 0.9 10.5 8.5 11.2 4.8 2.1 0.7 5.1 8.4 2.6 1.2 0.9 10.0 0.4 2.6 2.1 0.8 3.0 3.0 11.0 4.0 20.2 1.8 15.1 4.3 2.1 0.0 2.9 0.4 30.1 21.2 5.5 46.7 0.0 59.6 0.2 25.8 11.1 1.2 2.3 32.0 0.1 0.2 0.0 1.7 0.0 46.7 0.0 0.0 1.9 5.3 4.1 15.8 155.6 8.1 0.0 0.0 0.0 29.6 0.3 0.0 0.0 1.6 0.0 1.8 0.0 8.8 0.0 10.1 0.0 0.3 0.1 34.8 3.9 0.7 39.7 2.9 1.1 38.3 21.3 58.4 17.9 30.7 0.0 0.1 0.1 9.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 11.6 9.2 14.9 11.5 11.1 18.5 12.7 10.7 8.4 10.0 11.0 2.2 76.9 6.3 119.1 0.5 8.7 8.7 35.3 4.0 9.9 8.4 5.8 4.1 14.3 29.8 5.5 0.0 0.4 0.2 0.0 0.0 40.2 19.3 2.1 6.7 8.1 0.0 0.0 8.6 16.9 13.9 28.8 0.0 6.8 1.3 0.9 4.2 0.0 1.4 1.7 36.0 0.0 8.2 0.6 13.2 28.0 8.1 3.2 12.4 30.0 1.0 87.1 0.0 3.5 1.0 21.5 0.0 13.9 1.2 15.0 0.0 0.8 12.3 3.0 0.0 27.7 19.7 0.3 0.8 0.6 2.8 0.5 0.5 0.8 0.0 2.1 TGIF1 "HPE4, TGIF" ENSG00000177426 "TGFB induced factor homeobox 1" Q15583 18 3411608-3459978 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 783.4;Basal respiratory cells: 419.8;Basal squamous epithelial cells: 483.2;Urothelial cells: 426.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA062160 Supported Nucleoplasm NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "HPA062160: AB_2684701" "unprognostic (1.11e-2)" "unprognostic (5.20e-2)" "unprognostic (2.40e-1)" "unprognostic (1.97e-1)" "unprognostic (3.57e-3)" "unprognostic (3.10e-2)" "unprognostic (2.75e-1)" "unprognostic (4.34e-2)" "unprognostic (1.94e-2)" "unprognostic (1.96e-3)" "prognostic unfavorable (6.47e-4)" "unprognostic (9.60e-2)" "unprognostic (1.12e-2)" "unprognostic (9.81e-2)" "unprognostic (4.60e-1)" "unprognostic (7.07e-2)" "unprognostic (2.48e-3)" 51.2 40.1 21.7 43.3 20.8 41.5 57.6 22.4 25.7 68.9 30.2 51.5 31.6 51.2 133.7 46.7 74.7 65.3 29.8 20.2 29.3 74.0 61.5 47.6 26.4 29.8 27.3 67.3 46.9 26.9 22.0 63.8 25.7 54.6 65.7 8.0 56.5 56.1 34.4 60.2 37.8 37.4 27.5 35.5 49.1 25.9 25.7 40.0 66.7 26.9 27.0 112.1 40.0 28.4 33.6 148.5 92.7 29.3 90.0 121.7 235.7 63.1 236.6 49.9 62.1 61.0 142.6 1.9 20.9 49.8 165.7 33.7 35.0 73.8 61.6 13.9 16.8 4.3 73.2 110.5 178.8 47.6 38.3 89.5 291.7 89.7 233.7 131.3 104.4 22.3 36.0 0.4 95.6 65.8 31.1 58.8 240.8 119.0 34.8 32.8 43.2 10.3 198.1 156.7 27.1 26.5 166.2 123.0 92.5 151.3 28.1 43.7 49.6 77.5 65.6 92.7 41.1 5.0 0.6 15.7 78.5 18.6 98.2 65.4 42.8 7.6 62.9 16.6 67.8 46.5 52.5 61.9 35.1 32.2 37.1 43.5 19.8 21.5 16.7 3.3 32.1 36.3 21.7 20.8 22.4 25.7 20.2 29.3 29.8 27.3 25.7 27.5 25.7 28.4 41.0 35.3 40.2 8.1 106.5 359.6 783.4 419.8 483.2 0.0 114.1 72.1 5.6 100.1 128.3 123.2 0.0 161.6 60.1 30.0 49.0 117.1 41.5 167.2 58.5 66.6 46.4 25.7 2.7 75.0 220.9 102.8 79.0 240.2 68.0 71.5 29.3 35.7 71.8 1.7 0.6 99.4 136.3 44.9 221.1 9.7 28.6 126.8 76.5 7.5 71.9 6.7 11.3 4.0 1.7 106.0 53.0 15.4 15.1 308.1 24.9 113.1 93.3 0.1 32.9 90.9 86.6 7.9 15.4 223.9 257.1 150.4 103.7 8.0 91.8 426.2 TICRR "C15orf42, FLJ41618, MGC45866, SLD3, Treslin" ENSG00000140534 "TOPBP1 interacting checkpoint and replication regulator" Q7Z2Z1 15 89575469-89631056 "Metabolic proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.4;esophagus: 4.2;lymphoid tissue: 4.2" "Cell type enhanced" "Detected in some" "Erythroid cells: 6.5;Extravillous trophoblasts: 6.0;Granulosa cells: 5.1;Spermatocytes: 5.4;Spermatogonia: 5.3;Squamous epithelial cells: 8.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046746, HPA049454" Supported Nucleoplasm NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA046746: AB_2732533, HPA049454: AB_2680773" "unprognostic (3.52e-2)" "unprognostic (1.41e-1)" "unprognostic (3.77e-1)" "prognostic unfavorable (4.44e-4)" "unprognostic (3.41e-1)" "unprognostic (1.10e-1)" "unprognostic (6.22e-5)" "unprognostic (7.73e-3)" "prognostic unfavorable (2.87e-6)" "unprognostic (1.64e-1)" "unprognostic (1.31e-4)" "unprognostic (5.87e-2)" "unprognostic (0.00e+0)" "unprognostic (3.54e-2)" "unprognostic (7.38e-2)" "unprognostic (4.53e-2)" "unprognostic (3.59e-2)" 0.3 0.1 0.1 1.0 0.1 3.4 0.3 0.0 0.0 0.5 0.0 0.8 1.0 0.4 0.0 4.2 0.3 0.1 0.1 0.0 0.0 0.1 0.1 0.2 1.4 0.1 0.0 0.3 0.0 0.0 0.1 0.9 0.0 0.2 1.1 0.1 0.5 0.0 0.0 0.5 0.9 0.2 0.1 0.5 0.4 1.5 0.2 4.2 0.1 0.0 1.8 0.3 1.1 0.0 11.0 15.0 19.0 11.0 0.7 1.5 10.7 8.0 3.7 11.0 11.4 16.4 8.4 14.7 4.2 2.6 9.2 21.5 26.3 7.0 10.0 7.4 25.4 21.9 15.5 8.7 0.1 15.8 7.6 0.4 0.5 9.0 6.6 1.6 5.5 12.8 21.3 16.6 6.4 10.4 13.9 13.3 12.7 11.0 7.6 19.6 17.1 11.8 2.6 15.5 8.1 8.0 19.0 10.6 3.1 13.9 7.9 10.5 3.3 11.9 14.8 24.4 16.5 3.9 8.0 12.3 4.1 13.2 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.2 1.2 0.0 0.3 0.8 1.4 0.0 0.0 0.0 0.0 2.0 0.0 1.4 0.0 0.0 1.7 0.1 0.3 0.3 0.0 6.5 0.4 0.0 6.0 0.5 2.0 0.3 0.0 5.1 0.0 0.0 1.3 0.0 0.6 1.6 0.0 0.0 0.7 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.2 0.1 0.0 2.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.5 5.4 5.3 8.6 0.1 1.0 0.1 0.1 1.6 0.1 TIFA "MGC20791, T2BP, T6BP, TIFAA" ENSG00000145365 "TRAF interacting protein with forkhead associated domain" Q96CG3 4 112274537-112285904 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 86.6;Syncytiotrophoblasts: 79.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 137.4;U-698: 123.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045889 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Nucleoli" Cytosol "HPA045889: AB_10963785" "unprognostic (2.41e-2)" "unprognostic (2.47e-2)" "unprognostic (4.13e-2)" "unprognostic (3.23e-2)" "unprognostic (2.86e-1)" "unprognostic (4.98e-3)" "unprognostic (1.05e-1)" "unprognostic (2.25e-1)" "unprognostic (2.48e-2)" "unprognostic (2.14e-2)" "unprognostic (4.60e-3)" "unprognostic (5.26e-2)" "unprognostic (6.44e-3)" "unprognostic (1.52e-1)" "unprognostic (2.56e-1)" "unprognostic (2.99e-1)" "unprognostic (8.49e-3)" 6.4 6.3 2.0 19.9 1.8 40.6 13.7 4.3 2.1 7.7 4.3 7.0 6.7 5.6 2.1 15.6 6.8 7.5 10.7 2.3 2.4 5.2 11.3 10.2 32.2 2.3 2.1 9.3 41.3 11.5 2.1 14.2 2.5 6.7 6.9 2.8 34.8 3.7 3.8 9.3 8.8 5.3 2.1 11.7 10.3 2.1 2.3 15.4 21.1 6.4 34.6 11.6 7.7 2.3 21.9 5.5 7.9 13.4 9.5 7.7 15.9 17.0 32.0 10.6 18.1 2.8 19.1 66.3 13.5 6.8 15.5 6.3 10.9 13.0 22.1 54.1 6.4 6.6 12.4 6.2 6.4 21.2 8.8 10.4 7.0 11.4 12.3 18.0 17.0 18.1 6.8 137.4 14.3 11.0 37.3 11.5 1.6 13.4 7.0 63.7 19.9 44.7 23.6 14.7 18.1 18.6 13.7 28.2 6.6 3.4 12.2 29.9 12.7 16.7 19.8 14.2 13.6 85.3 84.8 123.8 15.7 13.8 12.6 6.8 7.2 4.0 11.1 5.2 18.1 38.2 20.4 19.4 13.2 40.4 9.0 11.6 21.4 17.4 6.8 12.3 33.9 11.3 2.0 1.8 4.3 2.1 2.3 2.4 2.3 2.1 2.5 2.1 2.3 2.3 35.7 19.2 27.4 0.0 44.8 21.3 15.7 27.8 43.9 1.4 31.6 30.9 15.4 12.8 15.7 12.9 0.0 47.9 23.4 4.4 19.6 16.5 0.1 10.0 9.6 31.8 9.0 7.6 1.4 24.4 20.9 22.3 14.8 21.0 3.8 5.4 6.4 10.7 17.8 0.0 0.6 8.4 28.5 13.0 29.7 1.4 9.0 13.1 33.8 2.8 7.1 12.5 11.3 0.5 0.1 11.4 8.0 10.9 86.6 29.2 11.0 9.5 8.8 0.6 6.6 27.2 10.5 2.5 3.8 39.2 26.0 79.4 35.9 5.7 7.0 15.1 TIPIN FLJ20516 ENSG00000075131 "TIMELESS interacting protein" Q9BVW5 15 66336191-66386746 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 98.0;Langerhans cells: 93.7;Spermatocytes: 120.6;Suprabasal keratinocytes: 108.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039704, HPA058799" Enhanced NA Yes "Cluster 24: B-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA039704: AB_10795258, HPA058799: AB_2683824" "unprognostic (3.47e-1)" "prognostic favorable (4.15e-4)" "unprognostic (3.49e-3)" "unprognostic (6.34e-2)" "unprognostic (1.87e-1)" "unprognostic (5.14e-2)" "prognostic unfavorable (2.47e-4)" "unprognostic (3.75e-1)" "unprognostic (1.32e-3)" "unprognostic (1.42e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (9.35e-4)" "unprognostic (2.18e-3)" "unprognostic (9.47e-2)" "unprognostic (1.09e-1)" "unprognostic (4.91e-1)" "unprognostic (2.89e-3)" 4.2 4.4 3.3 7.1 3.3 12.6 5.9 5.4 4.6 3.9 2.0 4.8 2.8 4.7 1.8 4.9 5.5 2.6 3.1 3.2 3.1 4.0 4.9 3.5 9.5 3.2 3.9 6.4 4.7 5.2 3.2 3.8 3.1 3.5 5.3 8.1 3.3 3.2 4.0 3.9 3.0 4.4 2.9 3.7 3.8 20.5 3.2 7.8 4.4 4.8 10.8 3.6 3.3 3.7 28.6 33.9 36.9 17.7 6.4 13.6 30.2 39.1 16.0 54.8 48.0 49.9 32.1 58.5 27.8 14.9 31.9 44.8 94.2 34.1 51.7 39.0 52.4 51.7 33.0 28.0 12.9 54.4 17.1 17.5 11.1 51.2 41.2 7.8 23.0 47.6 43.6 27.4 47.8 32.7 50.3 35.2 37.7 66.7 26.7 50.1 54.9 58.0 19.0 32.5 35.0 21.9 27.5 17.4 25.3 26.8 26.6 32.9 15.3 38.9 42.6 33.7 73.4 16.4 91.2 92.7 26.0 98.8 40.3 0.4 2.1 1.4 2.7 4.3 3.2 2.3 2.0 2.4 3.8 4.3 3.0 3.4 0.4 4.5 2.7 2.9 1.9 1.9 3.3 3.3 5.4 4.6 3.2 3.1 3.2 3.9 3.1 2.9 3.2 3.7 7.8 6.4 7.0 14.0 15.7 98.0 72.4 24.3 5.7 11.8 7.1 9.0 2.7 28.6 11.5 9.2 10.4 35.9 7.8 5.4 86.1 11.8 63.3 8.3 8.6 18.4 4.8 15.6 7.8 8.6 41.2 16.5 5.1 4.8 8.2 11.8 14.6 13.7 21.4 8.4 11.1 7.1 14.2 27.4 93.7 31.4 19.0 13.2 56.9 1.0 12.3 9.2 15.5 10.1 9.6 7.3 7.0 18.0 8.7 41.2 3.8 63.5 6.8 14.7 32.9 51.9 29.0 120.6 62.5 6.6 108.8 19.4 21.0 9.3 10.1 34.1 TK1 ENSG00000167900 "Thymidine kinase 1" P04183 17 78174091-78187233 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA synthesis" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 77.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 92.8;Erythroid cells: 108.6;Extravillous trophoblasts: 210.4;Hofbauer cells: 65.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 34.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Region enhanced" "Detected in some" "white matter: 3.6" "Low region specificity" "Detected in many" CAB004683 Enhanced NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "CAB004683: AB_437067" "unprognostic (7.09e-2)" "unprognostic (1.17e-3)" "unprognostic (1.82e-1)" "unprognostic (2.14e-3)" "unprognostic (3.22e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (6.87e-4)" "prognostic unfavorable (3.03e-5)" "unprognostic (4.05e-2)" "unprognostic (3.18e-3)" "unprognostic (6.64e-3)" "unprognostic (2.76e-2)" "prognostic unfavorable (6.50e-11)" "unprognostic (5.55e-3)" "unprognostic (1.92e-1)" "unprognostic (1.42e-1)" "unprognostic (4.94e-2)" 3.7 2.7 2.5 20.4 3.4 77.9 5.9 3.6 3.4 5.9 1.3 24.4 18.0 3.0 0.2 27.2 4.9 3.4 2.8 2.7 2.4 11.0 9.2 9.1 34.8 3.4 3.3 1.3 5.6 0.6 0.6 14.8 3.3 3.4 15.7 0.1 6.3 1.5 5.5 14.2 18.3 10.1 2.6 12.4 17.9 3.1 3.8 25.1 2.0 1.6 30.6 5.5 9.0 4.4 443.9 357.7 68.2 92.5 7.6 28.0 47.3 207.6 113.2 323.1 442.3 324.2 178.7 144.1 72.9 131.7 133.9 204.2 63.4 187.1 158.0 51.2 230.4 252.5 119.9 213.3 2.2 107.1 162.9 13.8 7.1 166.1 22.5 22.3 137.9 49.4 156.7 311.9 130.8 352.0 56.0 68.6 36.7 259.1 240.9 152.6 276.4 324.1 90.6 138.5 33.6 94.2 162.0 481.2 59.7 59.4 303.9 156.1 57.8 302.3 305.7 219.9 292.1 132.5 71.4 181.9 149.0 71.9 142.1 0.0 1.1 0.0 1.8 2.1 0.7 5.8 7.9 4.0 3.4 1.7 0.4 2.2 1.8 10.8 1.7 1.1 34.0 5.5 2.5 3.4 3.6 3.4 2.7 2.4 3.4 3.3 3.3 2.6 3.8 4.4 1.6 0.0 2.7 0.0 17.1 28.4 13.3 17.8 2.2 0.0 10.6 9.4 0.9 2.8 8.3 12.9 0.0 92.8 3.6 35.0 7.9 7.7 3.0 9.2 3.3 10.6 5.4 108.6 0.3 11.2 210.4 15.7 19.4 7.0 0.0 15.9 7.5 10.5 65.2 0.0 0.2 32.7 8.2 15.5 19.1 6.8 0.6 10.9 3.6 0.0 5.7 0.0 3.1 0.0 1.0 9.6 7.5 0.7 53.6 4.9 3.1 17.5 5.8 0.0 0.0 1.7 20.1 3.8 16.8 24.7 11.2 51.0 8.7 1.7 60.8 24.0 TLE3 "ESG, ESG3, GRG3, HsT18976, KIAA1547" ENSG00000140332 "TLE family member 3, transcriptional corepressor" Q04726 15 70047790-70098176 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 65.1" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 132.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 49.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 49.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054116 Approved Supported Nucleoplasm NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm "HPA054116: AB_2682386" "unprognostic (5.57e-2)" "prognostic favorable (2.09e-5)" "unprognostic (5.18e-2)" "unprognostic (5.13e-2)" "unprognostic (1.15e-1)" "unprognostic (4.05e-2)" "unprognostic (1.35e-2)" "unprognostic (5.53e-2)" "unprognostic (6.74e-2)" "unprognostic (3.11e-2)" "unprognostic (1.72e-1)" "unprognostic (6.07e-2)" "unprognostic (4.90e-2)" "unprognostic (2.43e-1)" "unprognostic (6.71e-2)" "unprognostic (6.29e-2)" "unprognostic (2.74e-1)" 16.1 6.4 9.2 18.3 11.5 65.1 15.2 10.7 10.9 17.4 2.9 20.6 17.3 10.8 3.0 31.1 10.1 5.8 9.9 12.3 15.3 16.4 13.3 20.3 17.7 15.1 13.9 14.0 14.9 5.8 10.3 12.6 11.8 23.2 6.4 4.9 19.1 10.1 8.3 29.4 21.8 6.9 13.4 23.1 15.7 22.1 15.1 13.5 13.5 2.9 18.9 9.8 19.4 12.2 7.8 24.2 13.3 23.6 12.1 9.9 80.3 1.5 4.1 3.1 2.5 34.0 22.8 22.0 32.8 2.1 4.8 14.3 32.3 11.5 1.6 30.9 45.9 36.9 50.8 6.6 11.5 11.4 51.1 20.5 6.3 9.1 8.2 19.7 15.5 47.9 26.1 96.0 4.5 20.9 41.2 28.3 14.2 7.4 24.9 36.8 13.6 24.7 7.1 41.7 19.5 28.7 66.2 29.7 28.7 14.5 33.6 24.9 11.7 9.5 18.7 29.6 16.4 84.6 57.2 35.3 13.3 37.3 25.1 2.6 4.5 2.5 1.9 4.8 1.8 9.9 2.6 2.5 2.9 4.9 2.5 3.3 49.1 2.8 5.2 8.7 1.6 1.7 9.2 11.5 10.7 10.9 12.3 15.3 15.1 13.9 11.8 13.4 15.1 12.2 27.5 12.8 27.7 16.0 49.2 115.1 47.8 19.5 59.2 19.9 45.5 28.4 8.1 4.3 18.9 62.5 31.3 25.3 38.2 55.2 7.9 11.6 45.5 17.2 5.0 27.6 28.8 15.2 6.1 5.6 64.4 25.0 17.9 32.1 53.2 25.5 23.9 21.5 37.3 0.0 5.0 30.3 10.2 41.5 78.2 76.9 14.0 51.5 35.6 13.1 35.8 32.6 1.0 9.5 0.4 11.0 31.7 18.4 47.2 39.9 41.0 13.2 8.1 4.4 0.0 39.8 24.7 5.8 28.0 67.7 132.8 82.4 37.6 0.7 43.9 31.5 TMEM106C MGC5576 ENSG00000134291 "Transmembrane protein 106C" Q9BVX2 12 47963569-47968878 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 244.8;Muller glia cells: 268.4;Paneth cells: 208.3;Proximal enterocytes: 385.7;Undifferentiated cells: 220.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-937: 876.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047204 Enhanced NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 32: U-937 - Innate immune response" "Cluster 45: Enterocytes - Digestion" "HPA047204: AB_2679982" "unprognostic (1.63e-2)" "unprognostic (5.84e-2)" "unprognostic (1.56e-2)" "unprognostic (2.40e-1)" "unprognostic (3.13e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (5.27e-8)" "unprognostic (1.05e-1)" "unprognostic (1.90e-2)" "unprognostic (1.52e-3)" "unprognostic (3.60e-1)" "unprognostic (7.29e-2)" "prognostic favorable (4.62e-4)" "unprognostic (1.12e-2)" "unprognostic (1.16e-1)" "unprognostic (2.57e-2)" "unprognostic (1.83e-1)" 28.1 41.9 37.4 36.3 37.5 48.2 66.6 38.2 46.1 52.0 56.7 138.2 113.2 35.8 135.8 42.0 48.5 45.5 58.9 39.7 42.4 80.9 44.7 39.4 38.4 36.4 36.3 55.5 66.5 146.2 62.9 73.4 37.1 41.0 145.3 121.7 59.7 51.7 26.5 37.4 120.1 55.3 35.5 78.1 53.5 40.0 43.4 55.9 49.3 34.3 46.8 28.9 32.8 33.7 243.9 166.4 151.7 167.7 68.5 50.0 143.2 133.6 191.0 238.5 203.8 250.2 243.3 212.2 182.9 147.6 221.8 162.1 239.2 146.1 226.6 203.8 229.1 163.7 217.2 101.7 52.4 172.6 117.9 34.4 98.4 217.8 114.2 163.4 154.2 224.0 113.4 235.6 169.6 174.4 248.2 75.5 27.0 258.7 226.5 217.9 195.9 180.9 127.2 183.2 100.9 120.5 206.8 138.5 142.4 78.4 503.5 136.9 38.3 99.8 168.9 145.0 240.9 130.8 228.9 240.1 127.3 876.5 97.9 39.3 8.8 23.9 44.4 8.6 54.9 36.9 42.8 46.5 12.5 30.8 39.7 44.0 7.6 19.6 10.4 1.9 66.4 41.0 37.4 37.5 38.2 46.1 39.7 42.4 36.4 36.3 37.1 35.5 43.4 33.7 14.5 32.1 20.7 6.8 26.5 47.9 39.2 45.8 36.5 30.2 54.9 78.7 39.1 61.5 21.9 35.0 18.8 75.3 17.7 244.8 86.1 63.8 2.8 35.7 5.7 17.3 36.0 49.2 14.1 45.1 32.8 45.4 37.2 18.6 10.8 86.3 55.0 19.6 54.3 30.3 13.0 150.8 101.7 16.4 20.7 6.8 32.6 21.5 21.4 8.4 10.1 268.4 27.8 4.5 1.2 35.5 208.3 41.3 72.5 22.6 385.7 82.2 11.5 47.2 13.1 46.4 36.9 52.8 36.0 55.4 40.9 14.9 31.5 35.0 220.5 39.4 TMEM138 "HSPC196, JBTS16" ENSG00000149483 "Transmembrane protein 138" Q9NPI0 11 61362344-61369509 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 194.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042373 Approved Approved Microtubules NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 46: Photoreceptor cells - Phototransduction" Microtubules "HPA042373: AB_10793880" "unprognostic (1.30e-1)" "unprognostic (4.69e-3)" "unprognostic (1.28e-1)" "unprognostic (2.78e-2)" "unprognostic (2.15e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (7.90e-4)" "unprognostic (1.06e-2)" "unprognostic (1.58e-1)" "unprognostic (1.86e-2)" "unprognostic (1.96e-1)" "unprognostic (1.71e-1)" "prognostic unfavorable (4.12e-6)" "unprognostic (2.28e-1)" "unprognostic (4.42e-2)" "unprognostic (3.49e-1)" "unprognostic (4.46e-1)" 13.8 40.6 8.4 11.5 8.5 18.1 14.3 10.3 9.7 16.3 10.0 13.4 10.8 17.5 25.9 10.8 17.3 11.6 9.1 8.7 9.1 17.9 22.2 15.3 18.0 9.0 11.0 23.7 13.9 18.4 12.6 14.9 8.6 17.1 18.7 50.7 11.1 13.8 6.8 18.6 15.9 18.6 9.0 18.4 13.5 12.5 8.9 14.0 13.5 8.5 22.8 17.8 13.3 9.5 16.3 35.5 14.0 20.3 48.9 20.1 16.5 24.9 30.7 36.2 32.8 17.7 24.6 14.0 21.0 29.7 56.5 30.2 26.0 31.0 39.8 18.0 14.4 10.1 28.7 21.0 35.0 21.8 26.3 32.4 47.7 60.5 39.4 13.5 31.4 16.7 29.8 23.0 60.1 45.4 17.3 21.6 22.8 28.2 34.5 11.9 10.3 30.4 32.3 39.6 14.9 11.1 31.7 30.4 34.2 12.8 47.3 19.0 18.7 45.2 18.7 31.5 24.7 24.0 24.6 13.6 23.7 26.5 24.0 41.7 26.0 26.5 23.1 26.6 25.3 26.1 21.7 22.3 15.9 24.1 24.0 21.4 5.3 27.8 18.2 28.0 30.2 24.1 8.4 8.5 10.3 9.7 8.7 9.1 9.0 11.0 8.6 9.0 8.9 9.5 12.6 16.0 23.2 16.0 23.1 19.9 16.1 49.8 25.0 28.9 15.7 17.1 4.2 4.3 26.2 20.2 81.3 54.8 27.3 13.9 15.6 17.1 21.7 22.0 16.6 18.7 9.6 22.1 12.5 16.0 39.9 20.5 9.2 7.0 37.3 17.8 13.6 16.3 45.7 15.2 12.1 11.6 16.2 15.6 10.7 7.6 31.7 35.6 37.4 3.7 25.5 25.9 36.0 10.1 8.1 18.6 11.5 28.6 18.1 22.1 26.7 20.8 59.6 194.1 0.0 15.3 14.3 24.9 16.2 16.3 20.5 27.5 23.3 56.9 14.3 12.9 TMEM243 "C7orf23, MGC4175, MM-TRAG" ENSG00000135185 "Transmembrane protein 243" Q9BU79 7 87196160-87220587 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 192.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 150.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014918 Uncertain NA Yes "Cluster 30: Non-specific - Translation" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA014918: AB_2067447" "unprognostic (5.14e-3)" "unprognostic (7.27e-2)" "unprognostic (1.36e-1)" "unprognostic (3.22e-2)" "unprognostic (2.59e-2)" "unprognostic (1.50e-1)" "unprognostic (3.39e-2)" "prognostic favorable (5.45e-4)" "prognostic unfavorable (6.84e-4)" "unprognostic (4.58e-2)" "unprognostic (2.69e-1)" "unprognostic (6.43e-2)" "unprognostic (1.16e-1)" "unprognostic (2.11e-2)" "unprognostic (1.41e-1)" "unprognostic (2.32e-2)" "prognostic favorable (9.13e-4)" 28.6 16.4 16.3 31.0 17.0 28.5 26.7 16.8 20.1 31.9 20.2 19.3 24.8 21.9 38.7 18.2 27.9 22.6 16.2 16.2 16.5 36.6 8.6 52.6 68.1 16.9 16.8 35.4 35.1 20.3 22.4 32.6 16.7 24.9 17.3 5.8 32.0 24.1 5.2 21.0 38.8 16.0 17.8 44.2 27.4 10.9 17.3 27.4 69.8 8.1 80.3 23.0 27.1 18.1 35.7 21.1 20.7 25.8 48.5 54.0 49.7 28.5 42.9 20.9 38.2 29.7 42.1 76.1 61.1 28.7 37.9 33.4 19.8 28.6 27.7 32.5 52.7 1.2 38.5 63.2 38.0 27.7 5.7 36.0 28.3 16.1 32.2 40.0 31.6 39.3 3.6 39.8 28.7 58.7 34.9 4.5 23.4 4.1 28.9 68.0 62.0 105.1 61.0 27.3 22.7 20.4 21.2 43.4 33.0 35.7 16.2 4.9 17.0 35.2 30.9 90.2 25.1 56.1 52.2 150.0 32.2 25.3 21.0 53.3 34.8 23.9 45.3 38.3 65.6 181.9 81.6 57.4 61.5 170.8 135.6 95.5 15.7 67.7 25.6 129.4 79.7 38.8 16.3 17.0 16.8 20.1 16.2 16.5 16.9 16.8 16.7 17.8 17.3 18.1 45.0 25.6 109.4 6.5 192.9 42.7 44.0 55.7 31.9 6.1 40.0 42.4 1.0 34.3 32.9 22.0 39.6 111.8 102.2 8.1 52.8 26.2 139.6 41.6 21.3 41.6 7.3 13.9 14.8 42.5 43.8 44.7 21.9 18.9 2.5 25.6 32.9 3.4 48.9 11.8 13.9 23.5 14.2 66.5 62.4 23.0 83.0 45.6 51.6 22.5 43.7 8.8 50.4 6.6 6.1 24.3 24.5 59.0 144.9 51.4 34.6 70.0 34.6 12.2 46.0 24.6 19.8 16.8 43.2 23.6 38.1 33.5 85.1 29.3 39.7 43.7 TMEM60 "C7orf35, DC32" ENSG00000135211 "Transmembrane protein 60" Q9H2L4 7 77793728-77798434 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062625 Approved NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 1: Thyroid gland - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" "HPA062625: AB_2684811" "prognostic favorable (3.09e-4)" "unprognostic (1.06e-1)" "unprognostic (1.42e-1)" "unprognostic (1.50e-1)" "unprognostic (1.02e-3)" "unprognostic (3.91e-2)" "unprognostic (5.28e-3)" "unprognostic (2.73e-3)" "unprognostic (3.46e-1)" "unprognostic (4.19e-2)" "unprognostic (1.06e-1)" "unprognostic (1.04e-1)" "unprognostic (1.21e-2)" "unprognostic (2.72e-2)" "unprognostic (9.44e-2)" "unprognostic (2.07e-3)" "unprognostic (4.43e-3)" 15.9 23.9 17.5 17.6 17.4 10.6 29.6 18.4 21.4 21.7 19.5 24.9 17.7 16.6 29.7 15.3 18.9 18.6 17.1 17.4 19.3 30.4 35.5 18.9 29.2 18.0 17.5 23.3 18.2 39.8 17.5 23.5 18.2 17.4 24.3 14.1 21.2 19.9 22.9 16.5 17.0 19.6 18.9 20.4 16.4 24.1 17.8 20.4 25.8 20.3 27.7 16.9 13.1 19.1 45.7 30.3 46.2 54.4 61.6 54.5 21.2 41.8 79.9 44.2 69.9 28.4 56.8 35.1 10.0 39.4 150.6 46.8 44.0 24.6 49.7 27.5 41.9 19.0 26.9 39.9 43.4 26.9 33.9 39.9 35.1 32.8 39.6 42.8 31.9 32.0 45.7 68.2 70.4 49.3 20.4 68.7 32.3 55.3 39.4 24.1 36.6 50.7 52.9 33.9 23.2 37.4 31.4 43.7 66.0 48.7 52.8 49.0 21.2 55.6 38.7 49.2 31.4 27.6 46.6 51.1 42.3 55.8 50.2 208.6 51.3 100.2 29.2 58.7 32.4 88.9 51.0 36.9 40.3 72.5 42.9 36.6 52.7 32.3 54.7 52.6 79.4 41.2 17.5 17.4 18.4 21.4 17.4 19.3 18.0 17.5 18.2 18.9 17.8 19.1 16.5 9.6 11.5 2.9 33.5 30.0 34.6 61.7 25.6 7.6 37.5 42.4 8.0 20.0 29.0 44.1 8.4 56.4 17.6 22.0 52.8 28.4 9.4 17.7 13.7 20.1 9.1 14.5 6.1 29.8 40.2 26.9 11.7 14.5 24.7 21.1 24.7 26.3 70.8 13.5 6.5 30.6 61.1 43.5 38.9 10.9 45.7 39.1 28.4 7.5 42.6 21.5 21.6 3.0 7.9 27.6 31.4 35.3 15.4 35.4 30.3 50.5 31.4 12.4 52.6 12.6 50.5 49.8 40.3 31.0 33.4 43.9 20.8 16.4 23.6 39.3 TMEM70 FLJ20533 ENSG00000175606 "Transmembrane protein 70" Q9BUB7 8 73972437-73982783 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "skeletal muscle: 100.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 78.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023187, CAB034226" Approved Supported Nucleoplasm,Mitochondria NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Mitochondria Nucleoplasm "CAB034226: AB_2205189, HPA023187: AB_2671101" "unprognostic (2.26e-3)" "unprognostic (4.87e-1)" "unprognostic (1.38e-2)" "unprognostic (1.11e-2)" "unprognostic (1.51e-3)" "unprognostic (8.22e-3)" "unprognostic (9.17e-2)" "unprognostic (1.01e-1)" "unprognostic (7.37e-2)" "unprognostic (7.04e-2)" "unprognostic (2.88e-2)" "unprognostic (9.14e-2)" "unprognostic (3.65e-3)" "unprognostic (6.86e-2)" "unprognostic (5.08e-2)" "unprognostic (2.13e-1)" "unprognostic (2.70e-2)" 18.1 18.2 9.2 9.8 9.7 10.4 11.3 10.5 12.3 8.0 9.5 12.6 5.8 8.9 10.6 9.3 11.3 8.9 19.3 10.3 10.2 12.0 24.4 9.0 10.1 9.6 9.1 10.5 25.0 8.3 7.6 10.3 10.1 7.4 9.7 6.1 9.9 5.9 100.7 7.7 9.5 9.1 9.5 9.6 17.8 9.8 9.5 11.0 6.0 20.5 10.3 11.3 7.4 10.1 21.2 16.4 13.1 13.8 14.9 12.7 13.6 17.6 15.8 19.4 15.3 15.8 11.9 28.4 15.0 12.0 16.4 19.1 24.9 16.8 21.4 18.9 17.5 28.3 10.0 21.2 14.7 15.5 14.5 11.8 15.3 12.2 6.4 7.3 16.4 14.2 22.0 13.5 20.5 15.9 35.8 29.6 12.3 26.6 20.6 25.4 12.8 24.2 20.5 20.0 29.7 13.1 11.0 78.0 23.3 10.2 16.0 14.1 10.6 11.1 13.7 20.7 16.9 19.9 18.7 28.1 16.4 12.1 12.5 6.3 9.1 6.7 8.0 10.2 9.1 17.7 9.0 9.3 9.6 10.9 10.3 9.6 6.7 5.8 7.9 11.0 7.9 12.0 9.2 9.7 10.5 12.3 10.3 10.2 9.6 9.1 10.1 9.5 9.5 10.1 136.2 16.0 30.1 5.5 37.1 67.3 43.7 54.8 24.5 23.9 26.2 22.2 46.3 14.3 35.7 22.0 8.4 71.2 48.1 69.0 66.5 36.6 20.3 40.8 26.2 96.4 13.8 26.5 12.8 63.5 59.6 50.2 17.3 17.1 39.9 17.0 28.5 50.3 132.4 10.1 11.4 31.7 42.7 70.0 74.5 12.1 29.8 73.2 40.9 5.6 38.9 23.1 22.6 3.5 8.1 43.6 37.9 29.0 68.6 42.1 28.8 75.4 58.7 17.5 39.5 61.9 40.8 70.6 29.5 21.5 59.7 70.3 39.8 52.6 34.1 26.2 TMPO "LAP2, LEMD4, TP" ENSG00000120802 Thymopoietin "P42166, P42167" 12 98515579-98550351 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" DNA-binding Cardiomyopathy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 139.9" "Cell type enhanced" "Detected in all" "Erythroid cells: 172.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008150, CAB009847, HPA070805" Enhanced Enhanced "Nuclear membrane" NA Yes 190000 "Cluster 51: Monocytes - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear membrane" "CAB009847: AB_2205450, HPA008150: AB_1079235, HPA070805: " "unprognostic (2.36e-1)" "unprognostic (4.46e-3)" "unprognostic (5.90e-2)" "unprognostic (2.80e-2)" "unprognostic (1.35e-1)" "unprognostic (2.95e-2)" "unprognostic (1.07e-2)" "unprognostic (1.54e-1)" "unprognostic (1.74e-2)" "unprognostic (3.69e-1)" "unprognostic (1.02e-1)" "unprognostic (3.67e-3)" "prognostic unfavorable (9.34e-4)" "unprognostic (6.01e-3)" "unprognostic (2.85e-1)" "unprognostic (5.26e-2)" "unprognostic (3.26e-2)" 17.1 13.9 8.4 44.0 9.4 93.2 24.3 19.1 15.1 23.2 10.1 34.5 34.1 30.8 34.4 27.0 22.8 17.7 11.0 9.1 9.6 21.7 37.2 21.9 78.7 9.7 8.9 56.2 25.3 17.8 8.4 29.4 9.6 17.2 36.4 20.7 16.5 19.1 12.2 22.7 39.6 22.3 8.8 39.1 35.7 23.1 9.6 139.9 15.2 12.2 78.1 20.7 20.7 14.2 180.5 117.5 283.3 145.5 23.1 30.7 166.2 145.0 77.1 193.9 139.5 129.5 88.9 314.4 86.2 85.6 70.7 113.0 240.8 110.1 177.1 217.7 148.5 269.1 103.3 86.5 21.2 315.4 170.8 17.6 35.4 115.0 61.2 66.9 112.8 192.0 231.8 118.1 122.0 114.7 514.9 248.6 170.1 167.2 108.6 421.3 187.2 218.6 69.3 167.7 221.9 132.2 248.9 155.2 79.3 110.6 174.3 149.2 60.4 111.1 96.5 76.8 150.8 125.9 231.9 344.0 32.0 179.5 151.0 48.6 30.4 13.4 18.9 54.1 20.5 22.4 21.9 21.6 23.4 27.2 30.0 23.5 2.4 20.7 75.9 12.9 28.5 30.5 8.4 9.4 19.1 15.1 9.1 9.6 9.7 8.9 9.6 8.8 9.6 14.2 45.4 32.1 27.9 3.6 70.1 27.8 23.7 18.7 28.5 21.1 21.2 28.6 9.0 25.8 33.5 31.3 12.5 36.0 48.5 63.0 31.3 19.5 42.7 29.5 29.8 38.0 28.7 172.1 20.3 31.5 89.7 32.2 56.1 42.7 29.1 70.1 34.2 50.0 38.2 10.1 15.3 63.4 16.2 63.1 34.9 32.1 28.6 73.4 17.8 23.4 63.5 20.3 54.6 14.6 19.1 26.7 28.5 40.6 81.9 21.1 33.7 33.1 25.6 52.6 19.7 27.3 32.0 54.0 59.4 62.8 23.3 11.8 60.8 32.4 62.4 21.8 TNFAIP8 "GG2-1, MDC-3.13, SCC-S2" ENSG00000145779 "TNF alpha induced protein 8" O95379 5 119268692-119399688 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 117.8" "Cell type enhanced" "Detected in many" "granulocytes: 211.8;Langerhans cells: 323.4;Syncytiotrophoblasts: 292.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 155.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054434, HPA057089" Uncertain Enhanced Nucleoplasm No Yes 470000 "Cluster 2: Granulocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" Nucleoplasm "HPA054434: AB_2682487, HPA057089: AB_2683331" "prognostic favorable (2.45e-4)" "unprognostic (6.06e-2)" "unprognostic (9.81e-2)" "unprognostic (1.57e-1)" "unprognostic (6.32e-2)" "unprognostic (1.08e-1)" "unprognostic (2.86e-3)" "unprognostic (4.92e-1)" "unprognostic (1.55e-1)" "unprognostic (4.45e-2)" "unprognostic (5.81e-3)" "unprognostic (4.47e-1)" "unprognostic (1.16e-1)" "unprognostic (1.18e-2)" "unprognostic (1.88e-3)" "unprognostic (1.64e-1)" "unprognostic (1.73e-2)" 72.4 5.1 4.2 62.3 4.1 65.5 19.3 8.9 7.0 15.9 31.2 17.8 16.1 13.3 17.1 25.3 10.5 16.6 8.5 3.9 4.0 16.4 10.1 19.1 117.8 4.9 4.1 3.5 16.8 14.8 1.6 52.5 4.8 18.9 19.0 2.4 11.2 14.4 3.3 31.6 31.3 15.5 1.7 61.1 28.6 17.5 5.1 100.0 25.3 5.6 115.9 43.6 17.8 6.6 27.7 19.0 10.0 16.1 20.5 17.2 91.2 15.0 40.4 11.1 23.0 10.2 31.6 51.0 4.7 16.7 17.6 38.4 8.3 45.4 15.7 56.6 17.9 81.4 41.1 17.6 9.9 99.6 86.4 19.1 42.0 33.7 15.9 21.2 15.4 99.9 32.0 155.2 15.5 10.7 84.5 128.9 15.0 16.0 8.9 25.6 44.1 75.8 44.5 54.8 5.1 7.8 56.6 10.9 5.5 32.1 9.4 111.4 8.1 20.2 7.8 14.1 17.9 76.0 90.0 103.3 23.3 104.8 11.9 491.9 96.1 305.0 111.0 105.1 217.3 267.2 221.9 164.7 133.6 243.5 260.8 169.7 54.6 111.4 86.7 63.8 188.4 213.0 4.2 4.1 8.9 7.0 3.9 4.0 4.9 4.1 4.8 1.7 5.1 6.6 8.9 9.6 18.7 1.6 174.9 160.5 80.9 81.9 123.5 0.2 14.4 10.8 10.3 12.8 38.3 18.4 0.0 142.6 83.6 2.7 17.6 55.4 4.4 11.8 7.8 23.2 1.2 34.5 0.8 101.0 158.8 30.1 17.9 9.5 211.8 0.7 6.4 1.9 48.9 0.0 2.3 9.9 20.3 59.4 323.4 1.4 2.1 126.0 37.4 24.4 196.6 4.3 111.2 1.0 6.8 125.7 2.7 1.9 45.6 63.9 0.9 19.8 47.2 0.4 46.0 4.0 32.9 1.1 18.0 93.1 119.2 292.7 139.0 35.2 4.3 103.6 TNFAIP8L1 MGC17791 ENSG00000185361 "TNF alpha induced protein 8 like 1" Q8WVP5 19 4639516-4655568 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 31.3;liver: 34.2" "Group enriched" "Detected in many" 5 "Early spermatids: 327.0;Late spermatids: 862.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 33.9;HUVEC TERT2: 33.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (1.39e-1)" "unprognostic (1.14e-2)" "unprognostic (3.70e-1)" "unprognostic (9.03e-3)" "unprognostic (1.00e-1)" "unprognostic (2.80e-2)" "unprognostic (8.39e-2)" "unprognostic (3.88e-2)" "unprognostic (1.82e-1)" "unprognostic (4.70e-2)" "unprognostic (3.70e-2)" "unprognostic (3.25e-2)" "prognostic unfavorable (1.28e-7)" "unprognostic (7.65e-2)" "unprognostic (8.99e-2)" "unprognostic (2.30e-1)" "unprognostic (3.22e-1)" 6.8 3.1 8.6 5.0 10.3 2.4 5.3 7.9 9.9 4.9 4.6 31.3 8.8 4.3 3.3 5.7 23.1 3.6 8.1 10.1 6.9 8.8 34.2 8.2 6.8 5.7 6.3 3.9 2.6 1.3 4.4 5.2 5.8 3.5 4.4 0.5 2.3 1.5 4.8 6.8 12.5 5.5 4.9 17.5 10.8 13.9 8.1 4.7 5.4 5.6 5.4 7.0 4.5 7.8 17.2 5.4 7.3 11.6 2.2 3.5 3.8 3.1 5.7 6.3 5.7 9.6 6.3 8.2 1.5 4.8 6.8 8.5 4.6 5.5 5.9 13.6 2.1 18.8 3.3 17.6 3.2 2.8 33.9 4.5 1.6 5.7 3.7 7.9 33.1 10.0 10.0 11.8 7.3 5.5 3.4 13.8 3.7 12.0 7.3 9.4 4.7 3.8 6.3 1.5 2.9 6.5 1.5 4.4 6.4 5.4 3.1 7.4 24.1 3.2 12.9 4.9 12.3 6.4 8.4 7.3 6.2 8.6 9.3 3.2 2.3 7.0 1.4 3.3 2.5 3.6 2.5 1.5 1.9 2.6 3.1 2.7 1.0 3.1 5.1 1.6 3.3 2.0 8.6 10.3 7.9 9.9 10.1 6.9 5.7 6.3 5.8 4.9 8.1 7.8 25.8 0.0 10.3 0.7 12.0 11.6 3.2 7.1 2.8 3.5 3.7 3.4 2.6 8.6 10.0 3.7 0.0 3.8 10.0 4.5 1.9 2.9 327.0 96.9 6.3 46.2 7.7 11.0 5.3 1.2 7.4 5.6 1.1 5.7 49.5 7.1 63.5 41.0 7.7 3.3 2.8 4.3 10.2 11.3 19.3 862.9 8.4 12.5 5.4 6.5 13.5 0.9 11.3 1.0 1.0 2.7 1.4 7.2 6.5 3.4 6.9 20.5 109.9 4.6 19.7 8.3 8.1 10.4 7.6 5.0 11.2 9.3 10.4 5.8 11.4 2.6 TNFRSF12A "CD266, FN14, TweakR" ENSG00000006327 "TNF receptor superfamily member 12A" Q9NP84 16 3018445-3022383 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation" "Developmental protein, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 612.4;Basal prostatic cells: 1315.6;Basal respiratory cells: 622.2;Ductal cells: 938.2;Exocrine glandular cells: 698.4;Pancreatic endocrine cells: 1232.3;Prostatic glandular cells: 757.9;Urothelial cells: 695.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "eosinophil: 139.6;neutrophil: 102.9" "Lineage enriched" "Detected in many" 10 "granulocytes: 139.6" "Cell line enhanced" "Detected in many" "U-251 MG: 699.6" HPA007853 Approved Approved "Plasma membrane,Cytosol" NA Yes 370000 "Cluster 52: Eosinophils - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 18: U-2197 - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA007853: AB_1858463" "unprognostic (1.44e-1)" "unprognostic (2.46e-3)" "unprognostic (8.90e-2)" "unprognostic (2.60e-1)" "unprognostic (4.06e-3)" "prognostic unfavorable (5.50e-4)" "unprognostic (7.04e-3)" "unprognostic (1.98e-3)" "unprognostic (4.17e-3)" "unprognostic (2.85e-1)" "unprognostic (5.02e-3)" "unprognostic (3.88e-1)" "prognostic unfavorable (8.78e-4)" "unprognostic (2.98e-2)" "unprognostic (6.00e-2)" "unprognostic (2.80e-3)" "unprognostic (2.17e-2)" 42.0 45.9 5.3 27.0 5.2 8.3 24.4 6.1 9.9 12.5 9.4 26.5 37.5 34.8 1.2 17.6 19.0 55.2 108.3 5.6 8.8 133.5 61.0 72.6 2.4 8.2 7.9 8.2 116.3 56.1 59.3 33.0 7.0 33.4 4.5 4.8 48.4 17.1 58.5 18.1 21.6 32.5 7.4 6.7 42.6 5.4 10.4 5.2 37.0 9.3 3.1 73.8 13.9 7.0 217.6 155.6 17.7 31.9 31.0 71.3 109.1 444.3 277.5 316.2 205.5 70.1 336.0 1.5 566.2 270.4 401.3 224.2 4.2 283.4 132.2 8.3 11.2 1.5 52.4 58.4 205.1 3.7 15.2 65.2 196.7 345.1 433.5 298.1 100.9 0.6 24.5 2.4 362.7 394.0 0.6 28.3 85.5 88.7 369.6 1.9 207.1 7.8 355.8 37.6 19.9 7.3 314.7 127.9 255.8 57.7 69.4 5.8 192.2 601.9 303.2 423.8 699.6 6.6 2.9 3.1 190.0 18.9 488.8 12.2 11.4 139.6 6.1 7.3 7.9 0.2 2.8 4.9 14.6 0.2 1.4 2.7 102.9 8.0 4.7 0.6 3.4 4.0 5.3 5.2 6.1 9.9 5.6 8.8 8.2 7.9 7.0 7.4 10.4 7.0 16.9 102.5 37.7 0.3 6.9 612.4 1315.6 622.2 113.3 1.5 139.0 46.7 63.9 195.9 238.7 182.1 2.1 134.6 10.0 74.2 64.6 938.2 1.3 170.5 29.4 47.5 27.3 1.3 0.2 698.4 169.5 155.1 33.1 173.1 59.1 3.0 24.3 20.7 39.7 0.0 0.5 19.9 152.5 5.6 121.4 0.8 6.2 23.0 112.1 1.9 10.8 23.3 4.1 0.0 0.1 1232.3 155.3 6.8 5.3 757.9 52.9 118.0 118.4 5.9 6.6 190.5 228.6 10.9 9.4 35.5 359.7 189.1 25.3 1.3 50.0 695.6 TNS2 "C1-TEN, KIAA1075, TENC1" ENSG00000111077 "Tensin 2" Q63HR2 12 53046969-53064379 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 109.3;Hepatic stellate cells: 93.1;Leydig cells: 141.7;Peritubular cells: 114.0;Sertoli cells: 151.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 114.2;ASC TERT1: 78.1;HHSteC: 59.9;HSkMC: 86.2;hTERT-RPE1: 61.9;TIME: 52.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034659 Approved NA Yes "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA034659: AB_10603349" "unprognostic (1.04e-1)" "unprognostic (2.58e-1)" "unprognostic (5.21e-3)" "unprognostic (1.86e-1)" "unprognostic (3.59e-2)" "unprognostic (7.26e-2)" "unprognostic (6.29e-2)" "unprognostic (5.42e-2)" "unprognostic (1.48e-2)" "unprognostic (8.97e-3)" "prognostic favorable (1.72e-4)" "prognostic favorable (9.32e-4)" "unprognostic (4.46e-2)" "unprognostic (1.09e-2)" "unprognostic (8.46e-2)" "unprognostic (1.47e-1)" "unprognostic (2.76e-2)" 156.3 66.9 59.3 14.8 66.2 0.3 121.6 46.4 57.8 121.2 33.3 79.0 14.4 98.8 14.0 28.3 121.0 32.5 99.6 43.7 49.2 67.3 66.5 83.4 15.8 58.0 63.5 104.1 34.6 17.0 43.3 33.1 54.0 66.3 11.5 6.0 35.7 41.1 69.0 42.1 56.7 28.5 50.8 79.5 58.2 15.9 58.3 7.2 80.6 58.8 6.4 82.6 81.1 57.9 2.0 21.2 2.7 2.2 114.2 78.1 0.7 11.8 27.1 6.2 3.2 1.4 5.7 0.1 25.3 32.1 2.6 1.5 0.1 7.8 2.4 0.5 0.8 0.4 25.5 11.3 59.9 0.3 0.5 86.2 0.3 7.9 4.7 61.9 36.3 0.4 0.6 0.3 24.9 5.1 0.2 0.4 1.9 1.4 5.8 0.7 6.6 0.3 8.2 0.4 1.2 2.7 4.4 2.4 8.8 1.6 26.1 0.7 52.1 12.9 14.8 4.7 2.0 0.6 0.3 0.1 20.4 0.3 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.3 66.2 46.4 57.8 43.7 49.2 58.0 63.5 54.0 50.8 58.3 57.9 109.3 3.2 25.7 33.3 0.5 0.0 6.8 0.0 5.2 21.1 15.1 13.0 7.9 10.0 2.5 5.5 0.0 0.5 0.9 0.4 3.9 5.8 2.8 4.4 41.1 69.6 1.2 2.7 3.1 4.4 0.4 40.5 2.0 14.5 0.0 7.7 93.1 37.5 2.4 30.3 7.8 3.9 0.0 4.4 0.0 7.2 141.7 2.9 0.0 31.9 0.1 29.6 0.0 46.3 35.6 2.4 9.0 114.0 1.8 4.5 2.1 2.6 1.5 11.3 151.2 51.3 64.7 4.2 4.4 1.3 0.0 0.8 1.4 2.6 1.8 2.1 TOB1 "APRO5, TOB, TROB, TROB1" ENSG00000141232 "Transducer of ERBB2, 1" P50616 17 50862223-50867978 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "T-47d: 253.3" "Low region specificity" "Detected in all" HPA047839 Approved Approved Nucleoplasm,Vesicles NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Vesicles "HPA047839: AB_2680175" "unprognostic (3.46e-1)" "unprognostic (1.09e-1)" "unprognostic (2.45e-1)" "unprognostic (6.78e-3)" "unprognostic (1.19e-1)" "unprognostic (8.27e-2)" "unprognostic (3.50e-3)" "unprognostic (1.53e-1)" "unprognostic (3.56e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (5.04e-5)" "prognostic unfavorable (3.37e-4)" "unprognostic (3.92e-3)" "unprognostic (9.44e-2)" "unprognostic (1.09e-1)" "unprognostic (4.13e-2)" "unprognostic (6.97e-2)" 42.6 210.2 32.6 22.3 34.9 70.2 65.3 31.6 40.8 55.3 59.3 47.4 56.1 23.9 26.5 77.7 54.6 47.6 44.7 29.8 39.4 67.9 168.6 36.8 18.9 37.3 48.2 63.4 207.9 81.4 50.1 13.8 38.6 72.3 57.5 101.8 99.8 92.2 178.6 133.5 48.1 29.4 31.8 17.8 87.5 26.0 33.4 17.7 95.4 109.9 21.0 81.9 70.9 40.2 44.1 88.7 28.1 11.5 51.4 25.4 22.0 31.9 79.2 20.5 25.0 36.0 54.6 40.0 60.6 43.9 20.7 61.0 19.5 54.1 21.1 20.4 29.3 4.8 100.7 60.5 72.0 21.5 18.9 54.5 65.5 23.9 120.0 27.3 9.9 12.2 17.0 33.7 43.4 119.0 16.1 19.4 10.2 109.4 33.9 14.0 35.6 47.6 80.9 89.4 16.6 40.4 55.1 158.9 19.9 42.5 253.3 27.1 13.2 23.3 16.7 26.7 15.8 51.9 57.7 18.5 19.2 10.2 9.1 417.7 53.5 285.6 245.8 107.3 269.9 40.7 222.7 192.5 119.1 31.9 192.1 233.6 130.7 28.8 152.5 38.5 206.0 169.0 32.6 34.9 31.6 40.8 29.8 39.4 37.3 48.2 38.6 31.8 33.4 40.2 101.6 115.4 118.3 71.8 53.1 283.2 232.9 119.8 284.0 125.3 180.6 179.6 115.5 210.1 81.8 68.0 56.3 20.8 124.8 183.3 103.7 42.6 97.9 143.7 51.7 40.7 203.4 18.1 11.5 54.1 2.0 83.5 123.3 176.2 63.9 19.7 33.2 205.6 35.4 18.5 14.1 223.2 48.8 27.6 249.2 40.4 26.4 89.9 71.2 5.6 29.1 118.3 20.6 16.6 34.1 41.8 186.7 59.8 41.3 187.2 126.2 60.4 87.8 62.7 164.3 137.3 123.8 36.9 12.1 153.8 230.7 10.9 154.7 77.4 167.6 287.2 TOB2 "APRO5, bK223H9, TOB4, TOBL, TROB2" ENSG00000183864 "Transducer of ERBB2, 2" Q14106 22 41433494-41446801 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016603, HPA054112" Approved Approved Cytosol NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 54: Non-specific - Microtubule organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA016603: AB_2669400, HPA054112: AB_2682385" "unprognostic (1.21e-3)" "unprognostic (3.10e-2)" "unprognostic (3.41e-1)" "prognostic favorable (3.08e-5)" "unprognostic (3.89e-2)" "unprognostic (1.38e-1)" "unprognostic (1.36e-1)" "unprognostic (5.36e-2)" "unprognostic (4.94e-2)" "unprognostic (5.74e-2)" "unprognostic (3.18e-2)" "unprognostic (1.17e-1)" "prognostic favorable (1.18e-6)" "unprognostic (1.50e-2)" "unprognostic (7.14e-2)" "unprognostic (1.85e-1)" "unprognostic (7.13e-2)" 46.1 31.3 39.3 15.6 56.3 9.7 25.5 78.1 40.1 26.5 18.5 30.1 22.4 25.0 11.8 26.6 38.4 28.8 41.2 39.3 43.8 24.6 27.1 20.7 18.5 61.7 42.9 38.0 29.0 35.6 22.8 22.0 44.0 26.6 15.5 55.0 17.2 19.4 86.5 27.1 23.9 20.1 39.5 20.6 30.5 13.6 52.0 19.6 36.1 68.1 19.7 23.3 21.0 71.9 36.8 16.6 28.5 19.4 65.4 45.5 27.5 23.9 36.7 29.8 26.2 21.9 17.0 22.4 23.5 34.8 11.6 31.4 26.7 13.4 27.1 23.0 34.2 12.3 23.9 33.4 44.8 33.5 15.9 42.1 22.5 35.6 15.4 30.1 30.2 7.6 18.9 24.5 24.6 40.8 13.9 19.2 24.4 48.1 17.6 29.7 19.2 19.4 21.3 25.3 13.1 8.8 60.0 32.2 44.6 17.7 17.9 16.5 37.9 29.3 27.1 23.0 22.7 22.9 10.7 12.2 17.8 14.2 19.7 3.9 5.9 4.1 7.5 8.0 7.1 10.0 6.2 6.3 5.3 7.5 3.2 4.7 3.8 3.8 8.4 8.0 5.5 6.1 39.3 56.3 78.1 40.1 39.3 43.8 61.7 42.9 44.0 39.5 52.0 71.9 48.5 48.1 59.6 48.6 61.4 126.8 66.6 24.3 105.3 56.0 83.1 56.9 59.8 58.6 31.7 47.8 64.6 34.7 56.9 76.9 23.5 29.7 41.1 88.6 59.3 45.3 54.3 16.8 12.2 19.1 37.3 54.1 42.3 116.9 34.1 13.7 52.5 29.7 19.6 25.2 15.1 67.7 10.2 22.0 117.9 61.6 66.8 51.4 53.4 14.0 34.6 58.3 18.6 10.1 43.6 32.3 60.0 82.0 26.2 73.6 103.6 29.2 45.9 105.2 52.6 97.4 60.9 23.8 28.9 88.7 136.7 63.3 57.4 19.6 61.9 92.2 TONSL "IKBR, NFKBIL2" ENSG00000160949 "Tonsoku like, DNA repair protein" Q96HA7 8 144428775-144444440 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.5" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 76.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA024679, HPA046494" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Nuclear bodies" "HPA024679: AB_1854441, HPA046494: AB_2679673" "unprognostic (6.68e-2)" "unprognostic (1.74e-1)" "unprognostic (2.40e-1)" "unprognostic (2.88e-2)" "unprognostic (7.35e-2)" "unprognostic (2.10e-3)" "prognostic unfavorable (2.84e-4)" "unprognostic (1.04e-3)" "unprognostic (7.81e-2)" "unprognostic (4.39e-2)" "unprognostic (3.38e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (2.62e-7)" "unprognostic (3.24e-2)" "unprognostic (1.78e-1)" "unprognostic (9.11e-3)" "unprognostic (7.96e-2)" 1.0 2.1 0.4 2.5 0.4 8.5 1.3 0.4 1.3 1.7 0.0 3.4 3.5 1.6 0.2 3.9 1.4 0.6 1.4 0.3 0.3 1.4 1.7 1.3 2.3 1.3 0.6 1.7 1.5 0.4 0.9 1.5 1.1 1.6 0.8 0.1 1.5 0.8 0.5 3.3 4.4 0.6 0.1 3.9 2.2 3.8 0.8 2.3 2.4 0.1 1.4 2.3 2.1 0.3 21.2 18.6 13.7 21.7 1.0 1.7 33.0 17.6 3.4 10.4 8.1 15.0 17.9 19.6 17.5 2.7 4.9 14.2 13.4 10.7 2.3 20.2 26.6 46.5 26.1 15.9 0.6 14.3 28.1 1.7 1.5 10.9 2.1 2.6 5.0 26.5 53.0 14.3 4.2 43.4 35.5 24.5 19.4 20.4 26.7 42.6 8.9 20.3 5.9 22.6 22.9 13.0 18.4 12.3 7.8 5.2 17.6 13.2 5.9 12.7 52.3 14.5 21.7 5.0 9.9 12.0 12.3 30.2 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.4 0.4 1.3 0.3 0.3 1.3 0.6 1.1 0.1 0.8 0.3 2.5 6.4 22.4 1.6 2.9 8.9 5.2 1.0 1.2 3.1 3.5 2.9 2.3 8.6 3.7 1.8 2.1 4.1 1.3 20.2 0.0 0.9 0.4 4.3 2.7 4.3 2.4 7.2 2.4 1.0 5.3 3.8 11.7 6.1 2.5 8.5 2.9 11.4 4.5 1.7 1.0 14.6 0.0 0.9 16.7 0.7 0.3 3.0 14.2 1.9 1.2 1.1 1.0 0.5 0.8 1.2 7.1 1.2 4.0 3.9 76.5 7.7 4.1 3.0 6.6 6.4 2.8 4.6 7.8 3.4 11.2 1.2 3.1 3.3 15.9 3.9 TOP1 ENSG00000198900 "DNA topoisomerase I" P11387 20 41028822-41124487 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 801.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009058, HPA019039" Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center" No Yes 7600 "Cluster 31: Non-specific - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 36: HEL - Hemostasis" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Nucleoli fibrillar center" "CAB009058: AB_2303554, HPA019039: AB_1858187" "unprognostic (1.46e-1)" "unprognostic (8.65e-2)" "unprognostic (1.33e-2)" "unprognostic (1.92e-3)" "unprognostic (5.05e-2)" "unprognostic (1.49e-3)" "prognostic unfavorable (6.42e-4)" "unprognostic (5.86e-2)" "unprognostic (1.51e-1)" "unprognostic (4.60e-2)" "unprognostic (3.74e-3)" "unprognostic (6.51e-2)" "unprognostic (8.65e-2)" "unprognostic (4.70e-2)" "unprognostic (5.14e-1)" "unprognostic (3.64e-1)" "unprognostic (1.29e-1)" 37.9 36.7 17.4 49.9 18.6 74.9 27.9 21.8 25.1 26.9 25.3 36.9 42.6 27.9 34.4 36.7 22.4 37.2 19.1 18.0 18.9 39.0 47.5 40.0 59.9 18.5 18.4 24.3 28.6 26.7 22.4 50.2 18.1 31.8 37.3 25.5 26.7 24.2 21.3 26.5 42.6 23.9 18.7 38.5 36.5 18.9 18.8 58.9 37.6 20.2 60.6 42.7 28.8 19.2 105.2 71.7 131.4 108.2 52.2 61.8 129.8 92.6 81.0 105.0 94.8 190.5 127.6 296.4 96.4 48.5 112.3 98.9 159.1 147.2 153.0 64.9 81.6 378.6 54.9 139.0 135.4 165.1 124.0 69.8 76.4 102.4 166.8 94.0 111.5 98.1 167.8 98.7 120.9 233.2 235.3 119.7 106.3 104.1 131.6 197.7 123.1 157.7 121.4 95.2 108.6 75.4 145.4 88.3 95.0 94.2 98.6 146.4 109.9 84.7 71.3 78.8 100.9 62.7 75.6 338.3 113.7 91.1 82.0 12.6 9.9 16.8 6.6 10.3 8.3 10.5 7.3 7.0 9.5 10.1 7.7 6.9 19.1 6.3 13.2 18.8 9.0 5.4 17.4 18.6 21.8 25.1 18.0 18.9 18.5 18.4 18.1 18.7 18.8 19.2 116.9 118.6 201.5 66.0 117.6 245.9 338.0 90.3 153.7 98.2 90.5 75.7 49.7 78.6 170.3 99.3 60.5 192.1 137.1 194.1 74.3 94.4 10.0 151.3 167.4 115.1 91.8 486.5 86.9 65.8 175.4 121.4 84.1 259.2 78.6 119.1 67.1 131.7 99.2 72.3 77.4 126.9 69.2 101.2 109.1 12.8 59.7 151.6 72.9 74.9 95.4 88.0 78.2 87.4 90.7 119.2 169.8 69.6 234.1 162.3 94.1 136.2 68.3 87.0 85.5 135.5 130.8 116.8 54.6 129.4 214.2 801.5 111.5 123.7 117.8 237.7 TOP2A TOP2 ENSG00000131747 "DNA topoisomerase II alpha" P11388 17 40388525-40417896 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 127.8;testis: 65.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 216.8;Granulosa cells: 117.5;Spermatocytes: 621.2;Spermatogonia: 269.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 2.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 4.2;white matter: 8.0" "Low region specificity" "Detected in some" "CAB002448, HPA006458, HPA026773" Enhanced Approved Supported Nucleoplasm,Nucleoli Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "CAB002448: AB_564035, HPA006458: AB_1858189, HPA026773: AB_1858190" "unprognostic (2.09e-1)" "unprognostic (1.24e-1)" "unprognostic (2.28e-3)" "unprognostic (9.42e-3)" "unprognostic (1.80e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.92e-6)" "prognostic unfavorable (4.99e-4)" "unprognostic (6.21e-3)" "unprognostic (2.09e-1)" "prognostic unfavorable (3.83e-5)" "unprognostic (5.03e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.46e-2)" "unprognostic (1.07e-1)" "unprognostic (2.18e-1)" "unprognostic (2.29e-1)" 2.2 2.5 0.2 20.0 0.2 42.0 5.4 0.1 0.7 5.0 1.1 17.8 18.1 3.9 0.3 29.0 1.5 2.6 1.2 0.2 0.2 1.2 2.8 4.1 40.3 0.2 0.8 1.0 0.9 0.3 0.3 15.9 0.5 1.4 19.8 0.1 4.3 0.5 0.3 15.3 17.0 7.6 0.2 9.9 8.9 65.7 1.1 127.8 1.9 0.2 42.5 6.0 9.6 0.4 212.6 275.6 343.1 158.0 16.8 33.9 76.3 283.3 151.5 255.0 224.2 130.5 157.6 339.4 140.1 96.7 152.7 326.5 266.8 113.5 339.5 182.7 177.8 224.8 167.9 216.7 1.6 318.4 228.6 7.4 9.2 179.8 181.4 55.1 136.3 216.5 247.5 225.8 279.2 72.6 372.3 209.6 143.0 152.4 108.3 310.7 531.9 141.3 61.6 133.3 201.6 144.6 229.3 281.4 89.4 198.2 236.9 143.2 90.3 167.0 233.2 195.5 276.7 128.4 154.9 290.7 94.3 214.9 285.0 0.2 0.0 0.0 0.2 0.0 0.0 0.6 0.3 0.3 0.1 0.1 0.0 0.0 0.1 1.4 0.1 0.0 2.4 0.4 0.2 0.2 0.1 0.7 0.2 0.2 0.2 0.8 0.5 0.2 1.1 0.4 1.0 0.0 2.0 0.3 17.4 11.7 3.7 15.0 2.2 0.0 18.7 17.1 1.3 2.8 5.8 0.0 0.0 72.9 6.1 19.8 0.0 0.8 20.3 12.7 15.8 9.3 0.0 216.8 0.2 0.0 92.4 23.3 23.0 10.0 0.0 117.5 20.7 5.4 83.5 0.0 0.1 34.2 18.3 33.9 13.2 19.1 4.7 14.1 1.8 0.0 2.6 0.0 3.1 0.0 0.1 0.3 3.5 1.9 31.3 3.1 3.4 0.1 1.8 0.0 72.3 0.5 19.5 621.2 269.6 45.1 6.1 8.9 14.8 4.3 61.0 6.9 TOR3A "ADIR, ADIR2, FLJ22345" ENSG00000186283 "Torsin family 3 member A" Q9H497 1 179082070-179098023 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 112.6;Plasma cells: 153.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 281.7;U-266/84: 322.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028766 Approved "Intracellular and membrane" NA Yes 24000 "Cluster 19: B-cells - Humoral immune response" "Cluster 52: Non-specific - Ribosome" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA028766: AB_10602251" "unprognostic (5.55e-2)" "unprognostic (6.52e-2)" "unprognostic (2.80e-1)" "unprognostic (1.59e-2)" "unprognostic (1.10e-1)" "unprognostic (3.90e-1)" "unprognostic (8.82e-3)" "unprognostic (6.47e-2)" "unprognostic (2.02e-2)" "unprognostic (4.87e-2)" "unprognostic (2.27e-1)" "unprognostic (3.99e-1)" "prognostic unfavorable (4.78e-8)" "unprognostic (4.26e-2)" "unprognostic (2.27e-1)" "unprognostic (3.58e-1)" "unprognostic (1.35e-1)" 17.0 15.5 16.9 30.8 17.9 39.7 19.5 16.4 18.6 16.7 19.3 26.1 23.3 16.1 12.8 15.8 17.8 18.1 12.8 17.2 19.4 17.0 27.8 20.4 46.4 18.3 17.2 14.8 23.4 22.5 16.9 15.3 17.2 17.9 26.0 9.5 23.9 17.0 24.4 17.8 23.1 18.8 17.6 37.4 26.5 4.3 19.9 26.7 18.6 13.9 44.8 23.3 13.5 19.3 56.8 65.5 18.6 52.6 38.2 29.9 57.1 41.4 50.0 48.0 34.8 29.8 86.4 90.0 70.2 41.1 28.9 68.5 53.7 34.6 25.3 70.8 49.4 98.3 38.5 45.9 62.9 109.6 80.6 33.1 31.0 35.3 31.9 19.2 35.5 34.8 123.9 164.3 33.8 121.4 66.3 60.5 38.6 68.0 36.4 49.4 33.9 88.4 30.5 76.8 37.8 49.3 61.9 96.9 25.5 32.5 71.5 80.1 22.0 36.2 25.6 59.9 54.3 281.7 322.8 77.4 25.1 77.3 26.5 5.2 71.3 19.3 33.6 56.5 41.4 97.8 29.9 37.7 85.7 73.1 22.7 27.6 14.1 31.5 59.4 93.1 43.3 53.3 16.9 17.9 16.4 18.6 17.2 19.4 18.3 17.2 17.2 17.6 19.9 19.3 24.8 3.2 11.7 4.9 65.2 17.0 14.0 19.2 10.8 3.7 14.8 11.3 11.5 25.8 11.1 11.0 10.4 30.1 32.5 18.6 3.9 34.0 1.1 10.6 16.8 19.3 14.4 18.3 4.4 44.5 57.5 19.8 20.9 11.1 10.8 14.3 13.9 10.7 57.4 0.0 4.6 18.9 32.6 22.0 112.6 1.1 17.1 36.4 16.0 5.6 50.6 17.1 16.5 3.0 4.0 18.9 17.9 18.8 153.7 19.5 15.1 10.3 13.4 9.6 6.6 18.9 17.3 0.8 5.3 12.7 15.8 10.9 24.8 21.2 27.0 12.3 TP73 P73 ENSG00000078900 "Tumor protein p73" O15350 1 3652516-3736201 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 8.0;fallopian tube: 6.7;skin 1: 6.6" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 13.0;Basal squamous epithelial cells: 16.5;Early spermatids: 21.8;Endometrial ciliated cells: 31.0;Late spermatids: 15.7;Respiratory ciliated cells: 35.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MOLT-4: 15.0;RH-30: 11.6;SCLC-21H: 18.0;U-698: 18.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB002514, CAB003022, HPA027314, HPA044516" Enhanced Supported "Nucleoplasm,Golgi apparatus" NA Yes "Cluster 27: Brain & Skin - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Golgi apparatus" "CAB002514: AB_563940, CAB003022: , HPA027314: AB_2672215, HPA044516: AB_2678971" "unprognostic (5.71e-3)" "prognostic favorable (2.98e-4)" "unprognostic (2.71e-1)" "prognostic favorable (1.82e-4)" "unprognostic (5.58e-2)" "prognostic favorable (9.50e-4)" "unprognostic (5.25e-2)" "unprognostic (2.18e-1)" "unprognostic (4.27e-1)" "unprognostic (1.99e-1)" "unprognostic (5.33e-2)" "unprognostic (3.99e-1)" "unprognostic (1.26e-7)" "unprognostic (1.77e-2)" "unprognostic (1.10e-1)" "unprognostic (7.33e-2)" "unprognostic (1.65e-1)" 0.0 0.0 0.7 0.7 0.5 0.5 0.8 4.2 0.5 1.4 8.0 0.2 0.0 0.1 0.1 3.7 6.7 0.0 0.1 0.8 0.7 0.1 0.2 0.9 1.0 2.4 2.9 0.1 0.8 0.1 0.3 0.0 1.4 2.6 0.1 0.2 2.9 0.3 0.2 6.6 0.2 0.0 1.4 0.7 0.3 0.7 0.7 1.6 0.2 0.0 1.4 0.1 2.9 1.0 2.6 0.1 0.3 7.8 0.0 0.0 0.6 0.0 0.0 0.0 0.0 10.9 4.0 2.6 2.0 0.0 0.9 4.3 2.7 0.9 0.0 0.8 8.7 0.2 3.9 2.6 0.0 0.0 2.9 0.0 1.7 0.0 0.1 0.0 0.0 0.0 5.6 0.0 0.8 1.9 15.0 2.0 0.5 0.0 0.1 0.0 11.6 0.1 0.3 3.8 18.0 8.4 0.4 0.0 0.8 0.0 10.9 9.2 0.0 2.9 7.5 0.0 5.8 3.3 0.7 18.5 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.5 4.2 0.5 0.8 0.7 2.4 2.9 1.4 1.4 0.7 1.0 0.0 0.0 1.5 0.0 1.2 3.1 3.8 13.0 16.5 0.5 0.2 2.5 1.5 0.0 7.4 0.0 0.0 0.2 0.0 0.5 0.0 0.0 21.8 31.0 0.3 0.3 2.4 3.2 0.1 0.2 0.4 0.4 0.0 0.7 0.0 0.1 0.4 0.2 0.3 0.0 0.1 0.5 2.0 0.0 1.3 15.7 0.6 0.1 1.8 0.0 0.0 0.2 0.0 2.5 0.1 0.2 0.0 0.0 6.8 0.2 0.0 0.1 35.8 0.1 0.0 0.0 2.6 0.1 0.4 1.6 2.3 0.3 0.4 0.1 0.3 0.2 TPX2 "C20orf1, C20orf2, DIL-2, p100" ENSG00000088325 "TPX2 microtubule nucleation factor" Q9ULW0 20 31739271-31801805 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 48.0;lymphoid tissue: 70.3;testis: 30.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 90.7;Extravillous trophoblasts: 68.5;Granulosa cells: 46.6;Spermatocytes: 114.5;Spermatogonia: 63.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 8.1" "Group enriched" "Detected in many" 5 "granulocytes: 5.1;NK-cells: 3.6;T-cells: 8.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005487 Enhanced Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cytokinetic bridge, Mitotic spindle" "HPA005487: AB_1858223" "unprognostic (2.18e-2)" "unprognostic (1.77e-1)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.43e-6)" "unprognostic (2.99e-1)" "unprognostic (7.56e-2)" "prognostic unfavorable (8.07e-7)" "prognostic unfavorable (6.46e-4)" "unprognostic (3.70e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.68e-5)" "unprognostic (5.99e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.56e-2)" "unprognostic (2.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.39e-1)" 1.9 1.4 0.9 13.0 0.9 48.0 2.7 0.8 1.0 2.3 0.5 11.6 9.4 2.4 0.2 13.2 0.9 1.8 0.8 1.1 0.6 0.7 4.2 1.9 26.6 0.6 1.0 0.5 0.4 0.4 0.2 8.3 0.7 0.7 14.2 0.5 2.0 0.5 1.4 9.8 9.4 6.8 0.6 5.2 6.2 30.7 1.3 70.3 1.0 0.8 32.3 3.4 4.1 0.9 455.1 149.1 176.4 139.1 13.8 25.2 169.8 186.1 104.5 264.0 197.7 319.1 190.4 212.4 106.7 104.5 196.8 232.7 203.7 169.0 298.8 92.3 78.8 416.3 139.7 219.6 4.2 161.9 102.8 8.7 9.1 166.0 120.0 37.9 144.6 157.1 313.8 187.8 209.7 186.2 272.2 125.3 197.1 174.0 159.3 152.5 475.5 128.2 71.2 72.8 127.5 85.7 284.6 106.3 82.0 120.9 185.1 97.3 98.3 294.1 179.7 136.5 290.0 74.4 138.6 187.3 92.2 565.1 195.8 5.1 0.0 0.4 0.4 0.0 0.2 0.6 1.4 1.7 0.5 0.2 0.3 0.5 0.2 3.6 0.1 1.0 8.1 1.0 0.9 0.9 0.8 1.0 1.1 0.6 0.6 1.0 0.7 0.6 1.3 0.9 1.0 0.0 4.2 0.0 5.9 6.9 1.5 4.3 1.2 0.9 3.0 3.4 0.9 4.3 3.8 0.0 0.0 23.3 3.8 6.4 0.0 1.2 9.3 7.3 6.6 3.9 1.2 90.7 2.9 0.4 68.5 9.2 16.3 8.4 0.0 46.6 8.9 3.0 19.5 1.7 0.9 9.8 10.2 8.0 5.5 13.1 0.9 7.6 0.0 1.0 2.1 0.4 3.1 0.5 0.5 1.8 1.4 0.0 30.8 2.5 0.9 0.0 0.7 0.4 0.0 1.1 15.4 114.5 63.1 31.2 6.1 4.7 8.2 4.2 18.4 2.9 TRIM59 "Mrf1, RNF104, TRIM57, TSBF1" ENSG00000213186 "Tripartite motif containing 59" Q8IWR1 3 160432445-160485773 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 68.4" "Cell type enriched" "Detected in many" 12 "Oligodendrocytes: 391.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017750 Uncertain Approved "Rods & Rings" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Rods & Rings" "HPA017750: AB_1858312" "unprognostic (3.74e-1)" "prognostic favorable (4.36e-4)" "unprognostic (1.76e-1)" "unprognostic (1.03e-1)" "unprognostic (1.10e-1)" "unprognostic (3.02e-1)" "unprognostic (8.00e-4)" "unprognostic (1.88e-2)" "unprognostic (2.02e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (1.15e-5)" "unprognostic (1.02e-3)" "unprognostic (2.44e-11)" "unprognostic (7.92e-2)" "unprognostic (2.42e-1)" "unprognostic (4.03e-2)" "unprognostic (5.91e-3)" 0.7 0.8 9.0 5.1 38.8 17.6 2.1 18.0 20.4 1.4 0.0 2.7 2.8 3.0 0.9 4.9 2.0 2.7 0.8 12.3 15.2 1.2 1.0 2.0 12.1 19.4 23.6 1.3 1.5 1.8 1.2 2.0 19.9 2.0 2.6 1.4 1.7 1.0 1.2 5.4 2.9 2.8 9.3 5.1 2.5 8.7 24.6 13.6 2.0 0.1 12.1 3.1 2.2 68.4 20.4 15.8 19.8 1.3 7.8 10.6 26.0 31.5 27.3 38.5 36.9 1.9 34.8 54.5 22.9 23.7 12.1 34.1 0.0 12.9 50.7 49.1 19.2 2.0 5.4 2.4 10.9 24.3 3.2 9.0 3.8 18.7 13.4 23.6 27.1 8.0 25.8 22.6 36.7 21.9 15.0 1.9 52.5 13.2 26.1 20.7 17.2 24.6 13.8 6.6 13.0 2.8 9.0 26.3 0.7 26.5 31.2 22.4 20.9 2.8 8.9 4.5 3.1 37.0 14.5 13.4 3.4 31.0 3.1 29.1 2.8 5.4 10.9 3.1 12.7 10.4 17.9 15.0 4.5 9.3 12.0 14.5 2.2 12.4 1.5 6.7 22.0 3.7 9.0 38.8 18.0 20.4 12.3 15.2 19.4 23.6 19.9 9.3 24.6 68.4 0.6 0.0 6.5 0.3 7.8 4.8 4.7 2.1 3.4 0.4 2.8 1.8 2.5 2.8 1.4 1.8 6.2 7.2 6.1 1.2 0.0 2.0 31.2 1.9 2.1 2.5 10.8 29.5 0.4 2.0 11.7 2.1 5.1 2.9 1.3 10.1 2.2 0.1 2.9 0.0 0.5 2.9 2.0 2.2 2.3 12.5 0.3 1.8 3.6 0.0 2.1 0.5 3.1 0.0 391.8 1.9 2.8 0.7 6.4 3.3 1.2 2.3 2.1 1.7 0.0 2.4 2.7 14.0 15.1 5.6 4.4 2.5 10.9 2.7 4.8 3.6 TROAP TASTIN ENSG00000135451 "Trophinin associated protein" Q12815 12 49323236-49331731 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 51.0;lymphoid tissue: 36.7;testis: 29.1" "Cell type enhanced" "Detected in many" "Early spermatids: 71.5;Erythroid cells: 75.6;Late spermatids: 70.2;Spermatocytes: 29.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 8.6" "Lineage enriched" "Detected in many" 4 "T-cells: 8.6" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA044102 Uncertain NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 21: OE19 - Mitochondria" "Cluster 12: Non-specific - Cell cycle regulation" "HPA044102: AB_10963691" "unprognostic (1.47e-1)" "unprognostic (2.76e-2)" "unprognostic (1.09e-1)" "unprognostic (3.92e-3)" "unprognostic (1.97e-1)" "unprognostic (4.29e-2)" "prognostic unfavorable (1.39e-5)" "unprognostic (3.43e-3)" "unprognostic (2.88e-2)" "unprognostic (2.65e-3)" "unprognostic (1.08e-3)" "unprognostic (3.51e-2)" "unprognostic (0.00e+0)" "unprognostic (1.80e-1)" "unprognostic (1.54e-1)" "unprognostic (1.92e-1)" "unprognostic (5.17e-2)" 1.3 1.5 0.2 7.3 0.3 51.0 1.4 0.2 0.7 2.8 0.2 6.7 9.0 1.2 0.5 13.5 0.7 0.8 0.8 0.2 0.2 0.9 1.6 2.4 11.2 0.4 0.2 0.8 0.8 0.7 0.4 5.1 0.3 0.9 9.2 0.6 2.5 0.4 0.3 7.7 7.6 2.8 0.1 7.0 5.4 29.1 0.5 36.7 0.8 0.3 14.5 1.9 5.3 0.3 95.9 73.9 92.4 69.7 2.8 6.2 71.2 45.4 43.4 129.5 73.1 163.7 73.5 64.6 21.9 33.7 70.7 74.6 70.4 44.0 75.7 51.9 101.8 90.9 120.4 53.7 1.9 66.5 93.8 1.5 6.0 86.9 59.8 21.1 75.1 68.0 57.2 108.9 52.7 123.0 122.9 101.8 43.4 269.3 110.2 62.5 78.6 83.9 31.7 35.0 59.9 41.0 56.0 107.4 32.7 53.6 88.2 50.1 25.0 33.5 91.2 69.4 124.8 58.3 68.8 83.0 32.3 73.8 38.4 0.2 0.0 0.1 0.1 0.0 0.2 1.4 2.1 2.3 0.3 1.4 0.1 0.5 0.0 2.0 0.1 0.0 8.6 0.5 0.2 0.3 0.2 0.7 0.2 0.2 0.4 0.2 0.3 0.1 0.5 0.3 0.1 0.0 0.0 0.0 4.6 3.8 1.5 2.8 1.2 0.6 2.1 2.8 0.5 0.0 1.8 0.0 0.0 14.1 1.0 3.7 0.0 0.7 71.5 1.9 1.3 1.9 1.2 75.6 0.0 0.7 23.6 3.3 10.2 2.7 0.0 16.0 5.7 1.1 15.7 0.0 0.0 7.9 10.2 6.7 3.7 70.2 1.8 4.0 1.8 0.0 0.9 0.0 6.2 0.0 0.0 0.8 1.8 0.4 17.0 1.1 0.7 0.1 0.2 0.4 0.0 0.7 3.5 29.1 9.3 15.6 2.0 4.0 2.5 0.9 12.7 3.6 TSPYL4 "dJ486I3.2, KIAA0721" ENSG00000187189 "TSPY like 4" Q9UJ04 6 116249964-116254075 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 109.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA044863 Approved NA Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "HPA044863: AB_10962578" "unprognostic (5.10e-2)" "unprognostic (2.05e-1)" "unprognostic (1.79e-1)" "unprognostic (1.65e-3)" "unprognostic (1.67e-1)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (1.80e-2)" "unprognostic (3.34e-1)" "unprognostic (7.41e-3)" "prognostic favorable (8.46e-5)" "unprognostic (1.30e-1)" "prognostic favorable (5.13e-7)" "unprognostic (3.34e-3)" "unprognostic (2.57e-1)" "unprognostic (3.61e-1)" "unprognostic (5.38e-2)" 8.2 35.4 57.5 7.5 61.8 10.4 14.0 56.2 109.7 17.1 15.5 12.3 5.8 21.5 18.0 11.6 21.0 10.6 20.4 62.8 72.8 14.9 9.0 10.2 10.3 44.9 55.9 25.4 12.2 28.7 28.4 10.7 60.0 22.4 8.1 30.1 9.6 18.5 5.1 10.5 9.3 15.4 43.1 11.0 15.3 14.8 69.5 17.7 14.3 7.8 9.2 11.8 11.9 48.5 6.2 3.4 47.6 39.7 19.2 16.4 8.9 24.3 16.4 30.6 18.2 9.6 5.9 5.0 9.0 37.5 16.1 13.6 20.7 21.6 45.8 20.7 7.0 10.1 18.8 22.7 15.1 19.1 6.4 16.0 10.0 23.7 12.0 23.9 21.0 28.0 15.7 16.4 25.7 19.2 36.9 11.7 11.5 2.1 8.1 20.9 2.6 4.9 9.2 9.0 55.9 37.6 21.6 9.0 4.3 16.9 16.3 10.5 24.4 25.4 21.3 14.6 14.1 6.6 8.2 0.8 11.7 12.5 16.2 0.5 2.1 2.5 3.2 1.8 3.8 2.4 3.9 3.3 1.9 3.0 4.1 3.1 2.8 3.8 2.8 3.1 3.6 4.0 57.5 61.8 56.2 109.7 62.8 72.8 44.9 55.9 60.0 43.1 69.5 48.5 7.0 3.2 7.7 11.8 9.2 4.8 11.9 4.9 30.1 21.4 11.8 13.2 44.2 11.5 7.2 11.0 20.9 3.3 13.0 3.2 19.6 5.4 20.3 30.8 31.9 11.5 31.7 6.1 16.2 7.4 2.0 13.3 8.6 25.8 11.4 27.5 11.7 3.7 3.6 40.4 16.8 5.8 6.1 6.8 3.5 6.7 10.2 8.8 5.4 7.5 5.9 20.7 6.2 4.5 8.5 7.1 2.5 10.9 7.3 7.0 0.7 6.4 27.5 28.7 0.0 14.8 16.8 20.1 3.6 14.1 5.3 3.4 11.9 18.9 4.5 8.0 TTC9C MGC29649 ENSG00000162222 "Tetratricopeptide repeat domain 9C" Q8N5M4 11 62728069-62740293 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055169 Approved Approved Nucleoplasm NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" Nucleoplasm "HPA055169: AB_2682724" "unprognostic (1.47e-1)" "unprognostic (1.02e-1)" "unprognostic (2.71e-2)" "unprognostic (7.23e-3)" "unprognostic (2.17e-1)" "unprognostic (6.56e-3)" "unprognostic (1.86e-3)" "unprognostic (1.52e-1)" "unprognostic (5.66e-2)" "unprognostic (6.90e-3)" "unprognostic (1.33e-3)" "unprognostic (1.57e-1)" "prognostic unfavorable (4.67e-7)" "prognostic favorable (4.15e-5)" "unprognostic (7.49e-2)" "unprognostic (3.55e-2)" "unprognostic (1.53e-2)" 12.9 14.1 17.0 18.2 17.5 5.6 14.8 18.9 21.7 13.7 15.9 16.0 20.4 15.3 17.3 14.4 18.4 15.1 11.3 18.2 17.7 15.0 13.4 12.4 25.9 18.7 17.6 26.2 13.3 9.4 11.9 19.3 19.1 12.1 15.5 9.9 14.9 14.2 16.2 19.9 15.4 15.6 17.4 19.7 15.4 14.0 17.8 25.1 19.3 13.7 23.9 15.9 11.5 18.4 47.4 39.4 32.8 31.5 46.6 54.3 24.4 48.7 49.7 57.1 47.6 35.0 45.0 35.7 88.1 33.5 50.7 41.2 49.8 14.8 44.9 93.0 24.8 39.3 57.1 43.0 51.1 26.9 41.1 35.8 31.4 46.3 47.1 42.5 43.3 42.0 29.3 34.3 54.2 33.9 42.5 55.2 27.4 38.5 31.5 32.5 42.3 54.0 36.6 18.0 28.3 23.3 41.3 35.3 57.1 29.1 46.5 24.8 36.9 56.5 33.3 64.0 34.1 36.4 58.6 40.1 31.3 20.2 30.5 70.1 39.1 40.5 22.4 36.4 17.6 42.3 24.1 22.9 33.9 37.9 23.6 21.7 25.1 29.9 24.3 33.9 39.5 24.7 17.0 17.5 18.9 21.7 18.2 17.7 18.7 17.6 19.1 17.4 17.8 18.4 14.5 16.0 10.9 7.8 27.0 29.6 13.3 14.2 25.0 17.5 13.8 13.8 9.3 10.0 17.3 18.4 8.4 35.0 21.8 17.0 27.4 24.0 23.3 14.0 14.4 19.6 6.0 14.1 18.0 14.9 41.9 18.5 7.7 10.9 8.2 22.6 13.6 9.9 38.5 28.6 13.5 15.8 18.3 27.1 20.6 20.4 28.3 18.8 16.0 4.7 40.5 13.5 35.0 7.5 9.8 19.7 15.3 27.4 22.4 21.3 25.9 27.0 18.2 16.0 32.9 10.2 17.0 32.4 31.8 21.2 33.2 23.8 21.5 19.6 17.7 19.6 TTF2 "HuF2, ZGRF6" ENSG00000116830 "Transcription termination factor 2" Q9UNY4 1 117060326-117107453 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation, Transcription termination" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA005776, HPA070762" Approved Supported Cytosol NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA005776: AB_1080416, HPA070762: AB_2686307" "unprognostic (1.82e-1)" "unprognostic (2.18e-1)" "unprognostic (3.29e-3)" "unprognostic (2.01e-3)" "unprognostic (4.90e-2)" "unprognostic (3.41e-3)" "unprognostic (5.27e-4)" "unprognostic (7.96e-2)" "unprognostic (1.92e-2)" "unprognostic (3.33e-1)" "unprognostic (4.64e-2)" "unprognostic (9.52e-3)" "unprognostic (7.34e-3)" "unprognostic (1.48e-3)" "unprognostic (7.73e-2)" "unprognostic (3.50e-1)" "unprognostic (3.65e-2)" 3.8 4.7 2.6 6.4 3.9 5.4 4.2 2.8 3.7 3.3 3.6 5.0 4.3 3.0 1.7 5.2 2.6 2.8 3.1 2.4 2.8 2.6 1.4 2.6 7.3 5.4 3.5 2.7 3.5 3.9 2.3 2.7 3.6 2.5 5.4 2.5 3.3 2.5 4.7 4.9 4.0 4.0 3.0 4.3 3.9 4.2 3.8 8.9 3.6 2.3 7.9 3.3 3.6 4.7 27.7 10.0 19.8 28.0 7.7 6.7 24.6 14.5 6.7 20.8 18.3 14.1 4.8 33.4 21.8 9.6 23.2 28.1 35.2 18.7 32.0 25.9 24.8 28.5 19.5 18.2 5.5 42.1 31.5 7.7 7.0 15.4 28.4 5.2 14.4 26.0 22.3 29.6 15.9 42.4 28.1 26.0 30.9 26.3 20.0 40.0 72.7 14.6 12.7 12.4 16.8 7.0 21.7 21.4 8.4 14.9 11.7 17.0 14.6 13.1 27.6 31.0 31.8 13.5 12.5 40.6 8.8 31.2 53.7 0.9 2.3 1.5 1.2 2.8 1.2 1.5 1.4 2.0 2.6 1.5 1.4 1.7 0.4 2.6 1.6 1.4 2.7 1.0 2.6 3.9 2.8 3.7 2.4 2.8 5.4 3.5 3.6 3.0 3.8 4.7 4.4 6.4 6.4 6.8 13.4 13.3 17.1 8.5 12.0 5.7 7.6 6.3 7.3 5.7 7.3 12.9 8.4 9.7 8.9 10.6 5.9 6.6 6.9 8.9 15.6 6.9 4.9 30.3 8.1 8.0 7.6 11.0 8.6 12.3 9.5 24.7 5.7 3.0 11.4 11.8 4.7 8.3 0.0 8.6 12.1 7.0 6.5 14.5 7.2 10.3 22.1 3.3 14.4 2.5 13.5 9.3 5.1 4.1 16.0 22.7 6.2 3.8 5.1 7.2 0.0 18.4 8.5 9.2 12.4 19.4 14.3 3.8 12.3 12.2 13.5 17.9 TTK "CT96, MPH1, MPS1, MPS1L1" ENSG00000112742 "TTK protein kinase" P33981 6 80003887-80042527 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 25.3;lymphoid tissue: 46.6;testis: 34.3" "Cell type enhanced" "Detected in many" "Early spermatids: 43.3;Erythroid cells: 23.1;Late spermatids: 21.4;Spermatocytes: 130.5;Spermatogonia: 33.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB010166, CAB013229" Enhanced Approved Nucleoli,Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli, Cytosol" "CAB010166: AB_632567, CAB013229: AB_2533230" "unprognostic (4.27e-2)" "unprognostic (8.71e-2)" "unprognostic (1.04e-2)" "prognostic unfavorable (1.44e-5)" "unprognostic (7.97e-2)" "unprognostic (4.78e-2)" "prognostic unfavorable (3.84e-10)" "unprognostic (1.56e-3)" "unprognostic (7.95e-2)" "unprognostic (2.02e-3)" "prognostic unfavorable (2.54e-4)" "unprognostic (1.54e-1)" "unprognostic (0.00e+0)" "unprognostic (3.51e-2)" "unprognostic (1.06e-1)" "unprognostic (1.46e-1)" "unprognostic (1.66e-1)" 0.7 0.8 0.0 4.2 0.1 25.3 2.2 0.1 0.3 0.7 0.0 4.8 4.0 1.0 0.1 4.8 0.6 0.5 0.1 0.1 0.1 0.2 0.5 0.8 8.1 0.2 0.1 0.2 0.2 0.3 0.0 3.9 0.2 0.8 5.9 1.8 0.7 0.1 0.0 3.6 4.1 1.7 0.1 1.4 3.3 34.3 0.2 46.6 0.4 0.1 9.0 1.2 1.4 0.2 39.9 23.4 68.2 56.4 3.1 9.5 38.5 44.9 27.4 64.2 77.8 32.1 29.6 58.5 34.1 19.5 66.9 50.0 60.7 27.6 88.6 53.4 49.3 54.1 29.4 26.5 0.2 64.4 33.9 1.2 2.8 45.0 28.6 9.6 36.9 80.6 60.2 58.5 55.2 29.5 37.0 46.4 40.4 35.4 27.9 32.7 124.4 24.4 16.3 25.2 46.8 27.4 26.6 28.3 16.3 36.6 26.6 48.3 15.4 28.8 28.5 18.8 72.9 13.1 47.1 32.4 10.3 58.9 25.1 0.0 0.0 0.3 0.1 0.0 0.1 0.2 0.2 0.4 0.0 0.7 0.0 0.1 0.0 0.3 0.0 0.0 1.2 0.2 0.0 0.1 0.1 0.3 0.1 0.1 0.2 0.1 0.2 0.1 0.2 0.2 0.3 3.2 1.1 0.0 1.4 1.3 0.6 2.6 0.0 0.2 0.9 0.5 0.6 0.0 2.3 0.0 2.1 9.8 0.8 2.2 3.9 0.4 43.3 3.1 1.6 1.1 1.8 23.1 0.2 0.2 15.0 2.1 2.6 2.3 1.3 13.9 0.7 0.2 6.5 0.0 0.2 3.0 4.1 2.6 1.2 21.4 0.9 1.9 0.0 0.0 5.2 0.2 1.0 0.0 0.1 0.6 0.2 0.7 5.1 0.4 0.3 0.1 3.0 1.6 6.6 0.1 1.7 130.5 33.0 8.5 0.3 3.7 1.1 0.5 5.6 1.6 TUBA1B K-ALPHA-1 ENSG00000123416 "Tubulin alpha 1b" P68363 12 49127782-49131397 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 2143.3;Extravillous trophoblasts: 2555.5;Hofbauer cells: 2114.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011513, HPA039247, HPA043684, HPA063394" Enhanced Supported Microtubules NA Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules "CAB011513: AB_2210057, HPA039247: AB_2676410, HPA043684: AB_2678617, HPA063394: AB_2685003" "prognostic unfavorable (5.49e-4)" "unprognostic (4.19e-2)" "unprognostic (3.84e-3)" "unprognostic (5.84e-2)" "unprognostic (2.91e-1)" "unprognostic (7.10e-2)" "prognostic unfavorable (1.68e-7)" "unprognostic (2.98e-3)" "unprognostic (9.28e-2)" "unprognostic (1.78e-1)" "unprognostic (3.69e-2)" "unprognostic (9.46e-2)" "prognostic unfavorable (2.85e-12)" "unprognostic (1.60e-1)" "unprognostic (3.52e-1)" "unprognostic (4.67e-2)" "unprognostic (3.55e-3)" 531.9 319.3 1071.9 650.0 1115.9 1491.9 453.7 941.8 1318.4 306.5 841.2 598.4 279.4 460.5 403.7 550.9 369.1 305.6 509.3 1108.8 1139.4 310.3 233.9 511.3 750.8 1176.0 1108.8 325.9 179.9 262.6 322.2 582.9 1162.2 247.8 665.1 652.9 304.6 394.1 243.9 404.3 352.5 1004.6 993.4 435.8 355.7 322.7 1127.4 1557.3 267.3 242.0 882.3 639.5 339.4 1076.7 3063.5 3381.9 3587.5 2051.4 910.0 1321.7 1939.2 2635.0 2642.5 5018.6 4034.6 4300.0 3144.6 3430.1 1854.8 3732.5 2047.5 1864.3 3993.2 3609.1 4586.7 1938.3 2103.5 2445.9 1822.2 2219.9 251.5 3705.8 1863.3 793.6 540.2 3930.9 1298.9 1697.4 4353.5 3121.3 2788.0 2182.3 4142.7 3362.1 4985.5 2943.8 2504.9 7570.8 3944.4 3980.1 3023.6 2137.4 2377.1 2008.1 2250.7 1921.9 2211.7 1697.3 803.9 1804.3 2403.1 3624.8 2321.3 2393.9 2752.4 2404.5 3470.2 1196.5 1876.2 3685.5 1668.2 2924.3 2303.6 197.9 240.0 411.5 241.8 1022.1 266.7 268.9 230.1 225.3 632.4 239.6 241.0 192.4 271.6 230.9 1107.4 632.0 293.2 731.1 1071.9 1115.9 941.8 1318.4 1108.8 1139.4 1176.0 1108.8 1162.2 993.4 1127.4 1076.7 702.9 198.7 231.8 36.6 445.8 584.0 653.7 875.4 288.5 426.4 267.9 391.8 0.8 90.1 373.4 187.6 492.1 1143.1 514.2 482.6 361.9 814.5 272.5 189.3 218.3 643.9 303.7 2143.3 201.8 630.1 2555.5 603.4 237.0 203.9 542.8 1069.6 353.4 106.3 2114.8 498.0 99.1 508.1 512.7 361.8 1353.1 204.8 326.8 729.8 473.2 68.4 1248.5 455.7 228.6 34.7 82.7 703.3 298.4 236.6 595.9 373.5 240.0 245.1 287.7 970.8 263.0 321.5 957.4 161.6 488.9 560.6 449.8 304.4 480.3 172.4 551.2 539.1 TUBA1C "bcm948, MGC10851, MGC14580, TUBA6" ENSG00000167553 "Tubulin alpha 1c" Q9BQE3 12 49188736-49274600 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 479.4" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 1118.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 98.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 4114.3" "Low region specificity" "Detected in all" "HPA039247, HPA043684, HPA063394" Supported Supported Microtubules NA Yes 160000000 "Cluster 38: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Microtubules "HPA039247: AB_2676410, HPA043684: AB_2678617, HPA063394: AB_2685003" "prognostic unfavorable (2.90e-4)" "unprognostic (1.15e-2)" "prognostic favorable (7.37e-5)" "unprognostic (3.25e-2)" "unprognostic (4.60e-2)" "unprognostic (2.88e-2)" "prognostic unfavorable (8.48e-8)" "prognostic unfavorable (6.85e-4)" "unprognostic (2.11e-1)" "unprognostic (1.53e-2)" "prognostic unfavorable (5.64e-6)" "unprognostic (1.49e-1)" "prognostic unfavorable (6.26e-7)" "unprognostic (2.95e-1)" "unprognostic (1.26e-1)" "unprognostic (2.49e-1)" "unprognostic (5.45e-3)" 92.6 57.8 12.4 110.5 12.1 148.8 54.7 13.9 18.0 101.0 41.9 158.2 106.9 59.6 62.7 479.4 50.8 92.1 55.3 12.8 16.4 113.5 69.3 74.1 78.6 15.7 14.1 38.3 52.6 22.5 28.0 109.9 15.5 43.7 156.5 2.5 139.0 46.4 45.3 166.1 117.6 129.8 15.7 42.1 115.2 26.3 22.6 103.3 56.3 42.5 170.7 222.5 168.8 15.4 1295.3 987.5 211.7 363.9 220.5 368.4 816.3 1010.1 1126.1 1742.1 927.3 966.9 947.0 578.9 1053.2 1194.2 1047.3 580.5 1246.0 1412.1 1150.2 564.1 449.7 703.4 406.7 943.7 165.2 550.9 498.4 269.8 663.0 1485.6 619.9 550.6 1139.5 320.6 1026.8 308.3 1521.8 811.1 306.5 535.8 639.6 4114.3 1928.6 344.0 414.5 319.7 770.3 602.8 169.8 9.1 875.5 574.4 386.0 828.3 559.4 426.0 835.1 819.3 911.5 821.9 1717.4 101.6 306.5 565.2 431.6 536.1 725.9 98.8 14.6 29.9 12.3 17.3 19.7 10.5 13.1 11.7 27.0 7.4 7.0 7.9 12.2 13.6 13.1 21.6 17.6 20.8 12.4 12.1 13.9 18.0 12.8 16.4 15.7 14.1 15.5 15.7 22.6 15.4 94.3 118.6 136.1 2.6 54.9 194.5 354.2 317.7 306.7 1.3 61.3 75.8 0.9 45.8 150.9 58.8 0.0 291.9 50.1 432.7 70.5 285.8 7.9 107.7 65.8 83.0 77.5 155.5 2.1 559.2 1118.2 109.7 153.4 204.4 67.2 110.8 39.3 55.9 276.8 0.0 1.9 190.5 101.7 65.6 121.7 8.4 68.0 163.3 46.2 2.8 265.5 2.8 6.2 1.0 1.4 465.6 330.2 40.6 71.0 206.3 234.1 137.1 51.9 0.6 39.5 84.3 258.2 9.0 65.5 530.8 183.1 161.6 77.6 46.1 187.9 293.4 TUBA3C "bA408E5.3, TUBA2" ENSG00000198033 "Tubulin alpha 3c" P0DPH7 13 19173772-19181824 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 714 "testis: 404.9" "Group enriched" "Detected in some" 25 "Early spermatids: 703.3;Late spermatids: 250.4;Spermatocytes: 947.8;Spermatogonia: 255.9" "Cancer enhanced" "Detected in many" "liver cancer: 2.7;testis cancer: 2.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 49 "HDLM-2: 107.5;U-2 OS: 256.9;U-266/70: 84.2;U-266/84: 109.7" "HPA039247, HPA043684, HPA063394" Uncertain Supported Microtubules NA Yes "Cluster 36: Testis - Spermatogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" Microtubules "HPA039247: AB_2676410, HPA043684: AB_2678617, HPA063394: AB_2685003" "unprognostic (3.76e-3)" "unprognostic (1.33e-1)" "unprognostic (3.00e-1)" "unprognostic (1.04e-1)" "unprognostic (1.26e-1)" 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.5 404.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.4 0.0 0.0 0.0 0.0 107.5 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.5 0.0 0.4 256.9 0.2 0.3 84.2 109.7 0.2 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 703.3 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 250.4 21.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.6 947.8 255.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 TUBB "M40, MGC16435, OK/SW-cl.56, Tubb5" ENSG00000196230 "Tubulin beta class I" P07437 6 30717435-30725538 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 2296.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005417, CAB012406, HPA043640, HPA046280" Enhanced Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes 170000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB005417: AB_2241191, CAB012406: AB_2210370, HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (1.01e-1)" "unprognostic (2.33e-1)" "unprognostic (2.17e-3)" "unprognostic (1.92e-2)" "unprognostic (1.56e-1)" "unprognostic (2.16e-2)" "prognostic unfavorable (5.97e-4)" "unprognostic (2.57e-2)" "unprognostic (2.52e-1)" "unprognostic (2.18e-3)" "unprognostic (1.27e-2)" "unprognostic (2.47e-1)" "prognostic unfavorable (2.62e-8)" "unprognostic (8.63e-2)" "unprognostic (1.47e-1)" "unprognostic (2.49e-1)" "unprognostic (2.50e-1)" 229.5 164.8 74.6 243.5 81.8 541.0 186.9 46.2 367.7 228.7 87.0 250.3 87.6 333.0 174.5 246.3 227.0 158.5 245.3 73.5 119.7 137.8 236.6 205.3 369.2 80.5 74.8 467.5 138.1 74.4 97.0 194.4 99.2 145.2 194.4 82.4 160.2 194.6 185.7 211.9 159.4 371.0 57.5 195.0 172.8 77.8 94.0 620.4 142.4 98.6 487.6 222.3 213.8 63.5 2281.7 1027.3 2650.0 1458.4 733.2 1265.2 568.2 396.9 469.5 943.3 863.5 1329.2 703.9 1494.1 1105.1 1408.1 1877.8 805.3 2160.6 1968.0 160.3 892.5 1321.1 461.4 207.3 1306.7 345.8 2550.0 1223.9 943.6 455.9 416.0 443.6 967.1 1493.3 2058.1 1270.4 294.1 1844.8 1398.2 2719.0 249.3 377.3 604.1 948.6 102.6 708.5 911.6 1564.5 1071.4 940.8 1516.7 969.0 911.2 354.7 1625.5 1148.3 422.4 880.6 2712.0 1526.0 614.5 917.7 835.3 1735.4 2101.3 538.8 2494.6 3548.7 119.8 115.6 122.8 187.3 182.5 218.8 166.1 152.3 188.8 111.7 113.0 143.2 163.3 46.8 165.1 222.4 227.7 180.8 342.5 74.6 81.8 46.2 367.7 73.5 119.7 80.5 74.8 99.2 57.5 94.0 63.5 215.8 131.4 47.3 21.5 214.9 576.2 358.4 698.6 434.2 72.7 234.2 312.8 114.9 244.5 238.7 171.0 39.6 811.9 198.7 133.4 311.0 1091.0 9.1 69.1 261.6 370.8 163.6 1322.1 28.2 1061.1 2296.1 471.5 95.3 140.2 207.3 643.6 298.4 267.8 955.2 109.4 25.0 185.3 376.4 454.5 689.6 24.4 402.6 295.8 321.9 30.9 774.0 192.6 246.1 20.1 23.0 1087.0 90.7 237.3 304.6 199.5 117.9 245.9 66.6 65.4 118.3 124.0 838.6 58.0 126.5 447.0 430.6 220.4 244.0 224.9 253.2 229.0 TUBB4B "Beta2, TUBB2C" ENSG00000188229 "Tubulin beta 4B class IVb" P68371 9 137241287-137243707 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Deafness, Disease variant, FDA approved drug targets, Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 2190.0;Late spermatids: 2907.1;Spermatocytes: 1717.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010880, HPA043640, HPA046280" Enhanced Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 38: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB010880: AB_609915, HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (2.24e-1)" "unprognostic (1.77e-3)" "unprognostic (1.50e-1)" "prognostic favorable (4.91e-4)" "unprognostic (1.29e-2)" "unprognostic (8.93e-2)" "prognostic unfavorable (9.98e-4)" "unprognostic (9.92e-3)" "unprognostic (2.90e-1)" "unprognostic (3.63e-1)" "unprognostic (2.34e-1)" "unprognostic (4.09e-2)" "unprognostic (2.47e-3)" "unprognostic (6.37e-2)" "unprognostic (1.36e-2)" "prognostic favorable (6.36e-6)" "unprognostic (1.69e-1)" 134.5 112.6 162.0 97.2 163.4 423.9 94.4 149.4 182.7 88.1 482.7 198.3 142.0 107.7 209.1 343.3 507.2 106.0 435.8 174.0 185.2 122.5 140.1 130.5 95.5 184.1 233.6 72.9 123.8 87.8 118.0 86.3 213.9 120.2 111.9 261.8 177.9 121.5 202.5 240.0 166.4 119.8 162.9 85.6 161.4 765.7 192.6 162.9 115.7 96.6 119.7 188.3 139.4 133.9 706.2 1032.5 431.7 314.2 213.2 223.6 600.5 643.7 536.0 872.4 598.6 1101.0 840.2 429.0 480.2 631.2 848.2 1305.1 539.5 1039.2 330.2 307.9 458.5 311.2 789.6 877.8 134.5 370.0 331.5 145.0 291.5 667.5 183.1 215.7 631.7 300.6 443.0 239.7 731.2 1936.4 337.4 504.2 457.8 1234.8 1778.1 423.5 822.2 394.2 666.8 647.8 301.5 323.6 853.9 485.8 173.2 244.2 699.0 397.6 495.6 618.1 685.0 710.0 863.6 92.4 274.9 475.1 503.6 286.9 549.8 95.7 30.0 43.2 40.5 30.1 38.2 32.6 31.3 34.4 34.9 30.8 19.7 26.7 56.4 24.4 30.5 36.3 44.7 32.6 162.0 163.4 149.4 182.7 174.0 185.2 184.1 233.6 213.9 162.9 192.6 133.9 478.5 221.2 146.3 21.5 315.8 326.2 945.7 458.7 327.2 508.1 286.9 389.5 91.9 143.0 284.1 143.5 300.3 346.6 640.9 744.1 221.1 348.6 2190.0 1191.6 224.8 203.9 391.5 419.9 30.1 446.8 545.5 247.8 274.7 415.0 189.2 200.9 142.5 139.2 265.9 244.0 24.3 503.6 323.5 59.9 214.9 2907.1 254.2 299.3 138.7 22.5 224.0 299.3 49.4 15.6 19.7 477.4 697.2 153.1 264.0 475.1 540.7 345.5 1558.7 763.3 111.7 261.8 416.0 1717.5 740.9 419.1 297.6 321.1 362.9 89.8 487.3 592.7 TUBB6 "HsT1601, MGC4083" ENSG00000176014 "Tubulin beta 6 class V" Q9BUF5 18 12307669-12344320 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 190.2;Extravillous trophoblasts: 494.3;Pancreatic endocrine cells: 221.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 157.3" "Group enriched" "Detected in many" 6 "B-cells: 58.7;dendritic cells: 157.3" "Cell line enhanced" "Detected in many" "TIME: 821.6" "Region enriched" "Detected in many" 6 "olfactory bulb: 19.9" "Region enhanced" "Detected in all" "spinal cord: 10.3" "HPA043640, HPA046280" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes 52000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (4.40e-2)" "unprognostic (8.28e-3)" "unprognostic (1.22e-2)" "unprognostic (5.20e-3)" "unprognostic (8.42e-2)" "unprognostic (3.37e-3)" "unprognostic (1.17e-1)" "unprognostic (2.74e-2)" "unprognostic (4.95e-2)" "unprognostic (4.90e-2)" "unprognostic (1.06e-1)" "unprognostic (4.25e-2)" "prognostic unfavorable (1.22e-7)" "unprognostic (5.83e-3)" "unprognostic (1.99e-1)" "unprognostic (4.94e-2)" "prognostic unfavorable (9.69e-4)" 197.9 37.9 12.3 82.1 11.7 34.8 134.6 14.7 14.6 106.5 28.6 193.6 31.4 173.5 24.9 217.5 121.2 66.4 166.2 11.8 13.7 66.0 40.8 92.9 31.6 19.2 16.3 81.2 52.7 5.6 33.1 59.7 15.1 84.2 28.8 3.6 69.6 91.3 37.3 78.2 75.8 151.9 14.1 34.0 89.1 28.3 18.4 12.2 52.2 20.2 31.3 129.9 124.2 12.5 211.8 142.3 149.5 76.1 149.0 208.8 108.1 648.5 424.2 492.0 459.1 113.0 65.2 1.3 281.7 440.8 148.6 99.5 84.7 653.6 380.6 1.8 46.1 32.3 159.2 73.6 151.0 2.7 59.5 219.1 146.0 429.4 222.7 148.8 366.1 12.5 159.7 2.5 432.5 216.1 0.8 162.4 79.1 3.3 70.0 1.6 260.0 2.2 99.7 5.8 19.3 27.2 360.3 34.8 113.9 153.7 76.5 203.8 821.6 600.0 510.6 565.7 574.2 11.5 3.8 3.8 458.9 46.9 219.8 2.0 19.4 0.3 0.6 7.6 0.3 42.0 0.1 0.2 25.5 58.7 0.2 0.3 0.4 0.9 7.5 157.3 0.2 13.2 12.3 11.7 14.7 14.6 11.8 13.7 19.2 16.3 15.1 14.1 18.4 12.5 67.0 83.3 7.9 0.7 16.1 69.6 42.7 151.4 16.5 1.2 30.4 44.8 54.3 8.6 37.4 7.3 0.0 53.8 23.6 0.6 1.9 167.6 190.2 6.4 76.9 128.9 0.0 12.2 0.8 104.9 494.3 112.8 1.5 7.1 45.6 7.4 82.5 0.4 69.4 0.0 0.6 0.4 42.7 13.2 85.2 114.9 70.2 36.5 33.8 12.2 65.9 0.2 0.0 0.5 0.4 221.1 0.1 91.4 1.0 51.5 0.1 1.2 18.2 1.6 26.3 89.2 130.5 4.3 6.3 55.7 66.9 22.2 3.6 9.5 0.5 65.2 TUBD1 "FLJ12709, TUBD" ENSG00000108423 "Tubulin delta 1" Q9UJT1 17 59859479-59892945 "FDA approved drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 83.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004609, HPA023980, HPA027090" Approved Approved Nucleoplasm,Cytosol NA Yes "Cluster 13: T-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Cytosol" "CAB004609: AB_628416, HPA023980: AB_1858456, HPA027090: AB_1858457" "unprognostic (1.92e-1)" "unprognostic (5.95e-2)" "prognostic favorable (2.04e-4)" "unprognostic (1.39e-1)" "unprognostic (1.32e-2)" "unprognostic (5.64e-2)" "prognostic unfavorable (1.00e-5)" "unprognostic (2.86e-2)" "unprognostic (8.87e-3)" "unprognostic (1.02e-1)" "unprognostic (1.77e-3)" "unprognostic (2.59e-1)" "prognostic unfavorable (6.06e-4)" "unprognostic (4.97e-2)" "unprognostic (1.63e-1)" "unprognostic (1.36e-1)" "unprognostic (8.83e-2)" 4.4 4.4 5.8 4.9 6.9 3.9 7.0 9.2 7.4 7.5 5.0 7.5 3.8 5.5 9.1 10.6 6.5 4.6 6.0 5.9 6.3 6.2 5.9 5.1 6.7 6.7 6.9 9.0 7.8 5.9 6.9 4.2 7.0 7.8 4.7 5.6 7.0 6.2 6.5 6.8 4.8 4.3 6.3 5.8 6.4 5.5 6.2 8.2 7.3 7.7 8.3 6.4 8.3 8.9 11.7 15.8 12.2 12.8 6.8 4.9 9.7 9.1 5.3 11.7 9.5 17.0 7.5 10.5 15.0 2.1 7.9 9.7 17.4 5.4 11.1 6.1 21.2 12.6 12.4 20.4 3.6 7.6 6.4 2.7 8.3 10.1 3.5 4.0 9.4 10.3 27.5 7.1 4.0 83.1 15.6 8.5 10.8 13.0 6.9 16.1 17.9 16.2 5.0 4.8 11.3 6.8 6.4 4.9 6.5 14.5 11.8 7.2 3.0 8.4 18.3 5.9 9.8 8.3 13.7 16.2 4.0 8.3 7.5 6.5 8.4 16.3 11.4 5.8 13.2 11.7 14.0 12.1 5.9 8.9 18.1 14.8 8.8 10.1 6.5 9.9 16.7 7.1 5.8 6.9 9.2 7.4 5.9 6.3 6.7 6.9 7.0 6.3 6.2 8.9 8.3 12.8 36.1 10.7 16.9 15.7 14.4 9.1 10.8 7.6 10.9 11.3 5.3 5.7 17.6 3.7 6.2 6.3 9.4 3.2 11.7 5.7 1.7 9.2 8.5 9.4 10.3 13.9 9.2 4.8 7.4 9.6 4.1 16.3 11.4 9.9 8.9 3.8 4.0 3.3 9.5 5.5 8.2 4.7 7.1 0.8 5.6 6.9 7.2 9.4 6.0 10.3 13.4 8.5 18.4 3.7 7.5 8.2 10.9 12.5 3.6 3.6 9.4 8.6 6.6 13.3 9.6 14.7 24.2 10.6 16.9 4.0 16.2 2.6 4.9 6.8 TUBG1 "TUBG, TUBGCP1" ENSG00000131462 "Tubulin gamma 1" P23258 17 42609641-42615238 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 173.8" "Cell type enhanced" "Detected in all" "Early spermatids: 670.6;Erythroid cells: 286.9;Late spermatids: 560.5;Spermatocytes: 347.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB004608 Enhanced NA Yes "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 34: Spermatids - Unknown function" "CAB004608: AB_628417" "unprognostic (1.00e-1)" "unprognostic (5.57e-2)" "unprognostic (1.79e-2)" "prognostic favorable (8.99e-4)" "unprognostic (2.86e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (1.08e-8)" "unprognostic (2.62e-3)" "unprognostic (5.67e-2)" "unprognostic (1.83e-1)" "unprognostic (3.79e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (6.48e-5)" "unprognostic (2.64e-1)" "unprognostic (3.52e-1)" "unprognostic (2.61e-3)" "unprognostic (1.97e-2)" 23.0 30.4 17.7 20.4 18.4 51.7 19.0 17.8 25.4 17.6 21.1 24.0 16.6 20.7 13.4 35.6 16.3 10.1 43.6 18.5 19.8 24.8 27.1 19.1 18.0 20.3 18.0 12.5 48.7 29.9 20.2 21.0 20.0 19.7 14.9 10.5 19.1 18.3 60.7 29.0 18.1 27.2 15.9 19.3 29.8 173.8 21.4 27.6 14.8 36.3 20.6 21.7 19.9 19.7 117.8 288.8 112.1 124.0 70.5 47.8 97.7 133.4 87.2 205.6 158.8 177.4 76.9 80.2 92.8 105.9 178.5 171.9 124.2 178.0 149.7 225.9 142.6 64.1 168.5 299.3 34.6 73.8 87.6 38.1 54.0 251.1 75.8 50.6 131.9 119.0 119.7 77.2 155.9 326.7 176.3 66.2 59.3 176.7 139.1 81.8 164.2 130.5 91.7 136.6 158.9 74.5 78.0 76.9 63.6 113.9 233.6 70.2 88.5 197.9 131.0 169.2 207.0 111.2 169.0 126.2 108.6 70.6 144.2 1.7 13.1 3.1 10.6 25.1 11.6 14.9 9.8 11.4 15.7 15.0 10.4 10.5 0.4 12.7 27.4 44.1 13.5 10.4 17.7 18.4 17.8 25.4 18.5 19.8 20.3 18.0 20.0 15.9 21.4 19.7 14.9 16.0 4.2 3.9 12.8 17.6 16.3 49.4 12.0 14.1 14.6 16.5 18.8 14.3 24.1 7.3 4.2 45.8 7.0 10.2 39.2 35.2 670.6 15.1 13.7 20.1 9.6 286.9 7.2 54.4 78.6 15.7 15.8 10.7 2.5 16.9 15.7 15.9 40.2 20.2 6.4 13.7 38.7 6.3 10.8 560.5 22.7 9.7 17.8 8.4 26.4 17.7 10.3 4.0 3.8 42.3 6.2 21.8 41.5 15.2 15.1 76.6 18.1 10.9 59.2 7.1 43.5 347.8 128.0 27.3 28.6 20.1 8.5 15.0 14.0 15.6 TUFT1 ENSG00000143367 "Tuftelin 1" Q9NNX1 1 151540305-151583583 "Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 111.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 69.2;Glandular and luminal cells: 76.8;Suprabasal keratinocytes: 66.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.2" "Group enriched" "Detected in many" 5 "granulocytes: 5.2;T-cells: 3.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 41.7" "HPA028112, HPA054301" Approved Approved Approved Vesicles "Secreted - unknown location" NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Vesicles "HPA028112: AB_10603224, HPA054301: AB_2682442" "unprognostic (6.16e-2)" "unprognostic (3.76e-1)" "unprognostic (1.38e-1)" "prognostic unfavorable (4.83e-4)" "unprognostic (4.49e-3)" "unprognostic (1.12e-1)" "unprognostic (2.30e-2)" "unprognostic (1.37e-2)" "unprognostic (8.29e-3)" "unprognostic (9.06e-2)" "unprognostic (6.70e-3)" "unprognostic (7.88e-2)" "unprognostic (2.58e-3)" "unprognostic (1.41e-1)" "unprognostic (1.32e-1)" "unprognostic (1.82e-3)" "unprognostic (4.53e-2)" 5.6 6.8 4.7 2.8 4.2 6.7 10.1 5.0 5.3 25.4 3.4 11.6 7.5 5.3 6.3 48.1 5.1 5.9 4.9 3.8 5.9 14.1 7.0 8.4 0.9 4.0 4.0 7.4 17.2 11.4 7.2 13.3 5.2 9.6 13.0 2.1 18.3 9.2 2.5 111.5 10.8 6.2 3.3 1.5 12.8 5.4 6.2 2.2 5.7 2.7 6.2 12.4 26.8 3.5 40.7 13.7 10.0 11.5 2.3 1.9 63.1 10.7 9.5 41.3 39.6 43.6 31.5 3.5 64.6 12.5 19.5 46.4 17.6 16.2 30.1 27.0 8.7 2.2 23.0 6.7 32.2 0.8 4.7 6.5 18.9 32.5 71.6 24.5 3.4 5.0 3.6 26.8 12.8 16.8 2.0 0.5 11.7 29.6 11.4 0.1 28.1 14.2 34.7 61.8 19.5 8.0 68.2 45.8 8.0 29.4 36.5 2.1 8.6 7.4 51.7 46.2 71.7 6.6 13.7 0.5 6.3 0.9 4.7 5.2 0.6 0.7 0.3 0.1 0.7 0.6 1.0 0.5 0.9 0.2 0.8 0.3 2.5 0.1 0.3 0.1 3.5 0.5 4.7 4.2 5.0 5.3 3.8 5.9 4.0 4.0 5.2 3.3 6.2 3.5 2.1 25.6 2.0 1.6 3.8 69.2 35.2 14.7 35.9 2.5 28.8 20.2 9.8 8.6 19.0 14.7 0.0 28.1 6.6 59.5 13.7 18.2 2.7 43.2 8.9 2.7 32.2 2.7 4.4 15.2 13.9 7.0 46.9 76.8 4.5 9.0 1.1 10.5 4.0 0.0 9.3 39.1 20.3 0.0 12.7 3.2 2.5 6.5 8.8 1.0 2.0 2.1 0.0 8.5 1.8 47.4 34.6 5.3 7.7 21.7 15.4 11.2 15.9 0.5 6.6 4.1 5.5 0.6 3.5 39.6 66.5 56.8 5.8 10.9 35.7 35.6 TXNL1 "TRP32, Txl, TXNL" ENSG00000091164 "Thioredoxin like 1" O43396 18 56597209-56651600 "Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002828, HPA002829, CAB016446" Supported Supported Enhanced Cytosol NA Yes 1100000 "Cluster 34: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB016446: , HPA002828: AB_1858358, HPA002829: AB_1858359" "unprognostic (2.05e-1)" "unprognostic (2.97e-1)" "unprognostic (3.38e-3)" "unprognostic (4.54e-2)" "unprognostic (2.51e-1)" "unprognostic (1.78e-1)" "prognostic unfavorable (9.62e-6)" "unprognostic (1.83e-1)" "unprognostic (1.03e-2)" "prognostic favorable (6.26e-5)" "unprognostic (1.44e-1)" "unprognostic (2.79e-1)" "unprognostic (3.29e-3)" "unprognostic (1.24e-1)" "unprognostic (1.26e-1)" "unprognostic (2.62e-1)" "unprognostic (1.51e-1)" 38.3 55.9 45.4 38.6 47.5 83.0 49.1 49.1 63.6 42.5 40.1 41.7 42.1 38.3 66.9 54.2 35.2 40.0 80.0 50.0 50.9 51.7 80.7 30.6 41.2 47.7 47.2 47.1 62.2 51.4 38.2 48.1 49.5 40.5 43.4 77.9 48.5 39.3 149.0 36.5 40.6 43.4 46.2 32.2 46.7 41.9 47.5 48.0 197.9 146.8 49.9 51.8 35.1 54.0 77.7 74.8 99.2 102.8 83.2 121.6 70.2 90.2 91.8 113.4 95.4 67.0 74.2 83.4 78.1 98.4 82.3 93.7 94.4 81.3 116.9 85.7 43.1 114.9 58.3 127.1 98.3 168.9 71.7 92.9 82.4 107.4 97.4 118.8 93.0 62.9 85.5 136.0 116.0 74.4 98.1 109.8 71.9 53.5 79.6 78.2 66.8 145.9 133.0 118.6 81.6 74.5 51.3 70.9 88.1 78.3 77.5 89.1 74.3 118.7 62.9 41.9 89.5 130.8 151.1 130.5 77.2 127.0 89.1 98.5 63.1 48.3 26.9 55.8 37.2 38.9 33.0 35.8 54.8 35.4 32.0 32.9 48.3 43.3 54.9 47.0 42.9 61.5 45.4 47.5 49.1 63.6 50.0 50.9 47.7 47.2 49.5 46.2 47.5 54.0 89.7 57.7 45.9 25.5 80.0 134.3 123.1 177.1 75.7 82.7 89.3 110.4 110.1 67.2 108.3 29.5 139.7 242.3 82.7 72.2 109.5 150.5 246.9 88.0 90.0 84.2 75.9 153.8 43.8 128.3 130.9 86.1 52.0 90.3 53.2 167.5 52.8 78.0 150.1 57.2 43.6 111.6 77.3 97.3 97.0 294.1 77.6 90.5 65.8 15.9 121.8 86.0 78.2 26.2 55.6 139.5 83.7 83.8 88.9 121.2 110.0 144.7 75.1 97.1 65.7 73.0 167.1 204.1 108.0 93.9 126.0 358.6 72.4 171.0 109.7 123.1 TYMS "HsT422, TMS, TS, Tsase" ENSG00000176890 "Thymidylate synthetase" P04818 18 657653-673578 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Nucleotide biosynthesis" "Methyltransferase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 88.5;lymphoid tissue: 113.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 105.8;Erythroid cells: 189.3;Extravillous trophoblasts: 115.3;Plasma cells: 112.7;Spermatocytes: 180.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 14.1" "Group enriched" "Detected in many" 6 "NK-cells: 6.7;T-cells: 14.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB002784, HPA074922" Enhanced NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "CAB002784: , HPA074922: " "unprognostic (7.58e-2)" "unprognostic (2.06e-3)" "unprognostic (9.31e-2)" "unprognostic (2.34e-2)" "unprognostic (7.35e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (5.10e-6)" "unprognostic (1.62e-3)" "unprognostic (1.68e-2)" "unprognostic (9.82e-2)" "unprognostic (1.07e-3)" "unprognostic (3.28e-2)" "unprognostic (1.23e-2)" "unprognostic (6.34e-2)" "unprognostic (1.66e-1)" "unprognostic (5.65e-3)" "unprognostic (2.47e-1)" 4.5 3.1 4.3 24.2 7.5 88.5 6.7 4.1 6.5 4.8 2.7 22.9 10.5 5.1 1.3 14.8 5.6 3.8 2.2 5.0 4.9 6.5 11.8 4.9 36.1 4.9 5.2 2.1 3.6 1.8 1.6 22.3 4.4 3.1 27.1 4.2 3.9 2.0 0.4 6.2 14.8 12.7 4.8 10.6 8.8 34.3 6.1 113.6 2.1 0.4 44.5 8.4 5.5 10.3 102.7 156.6 320.4 154.9 35.1 57.9 159.9 238.9 141.1 251.7 299.9 132.8 80.1 160.0 91.5 129.9 143.2 45.1 225.3 89.7 216.1 152.3 244.9 273.1 135.8 229.4 8.2 564.8 286.5 51.5 20.7 159.6 49.6 48.4 214.4 334.0 222.0 249.6 321.8 118.1 687.7 311.4 114.7 124.3 114.0 446.8 287.0 191.3 95.6 88.9 106.0 175.7 201.4 91.6 61.1 197.3 63.5 253.5 85.0 289.7 569.5 267.3 474.2 305.9 405.2 367.3 75.2 240.6 339.2 0.0 0.0 1.3 1.1 0.1 0.0 1.1 2.8 2.2 1.8 0.0 0.0 0.6 0.7 6.7 0.1 0.3 14.1 2.9 4.3 7.5 4.1 6.5 5.0 4.9 4.9 5.2 4.4 4.8 6.1 10.3 2.1 0.0 2.3 1.6 15.7 14.4 15.9 13.0 27.9 0.5 7.8 11.7 3.6 2.8 6.7 0.0 0.0 105.8 14.5 15.5 1.9 2.3 34.4 5.6 8.4 12.5 1.2 189.3 0.4 0.8 115.3 28.3 14.3 7.4 7.0 76.2 6.8 4.3 71.4 0.0 0.6 20.9 10.2 15.6 19.4 31.9 6.2 10.7 10.6 1.0 3.9 45.0 5.2 0.5 15.6 1.5 8.9 3.8 112.7 5.0 13.8 36.6 1.0 2.4 13.1 1.3 32.6 180.8 30.7 48.0 7.2 27.0 21.3 10.5 54.9 18.7 UAP1 "AgX, AGX1, SPAG2" ENSG00000117143 "UDP-N-acetylglucosamine pyrophosphorylase 1" Q16222 1 162561506-162599842 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-HME1: 678.4;U-251 MG: 463.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014659 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No Yes 48000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Plasma membrane, Cytosol" "HPA014659: AB_1857409" "unprognostic (2.32e-2)" "unprognostic (2.45e-1)" "unprognostic (2.07e-2)" "unprognostic (1.28e-2)" "unprognostic (2.71e-2)" "unprognostic (1.46e-2)" "unprognostic (1.37e-2)" "unprognostic (1.47e-1)" "unprognostic (2.09e-1)" "unprognostic (1.30e-1)" "unprognostic (1.29e-3)" "unprognostic (4.96e-2)" "prognostic unfavorable (5.12e-5)" "unprognostic (1.59e-1)" "unprognostic (2.04e-1)" "unprognostic (3.51e-1)" "unprognostic (3.45e-2)" 96.0 43.7 12.2 33.7 13.2 51.5 58.8 13.5 14.9 37.1 16.1 65.6 43.9 18.6 29.1 33.9 33.1 39.8 45.1 13.4 13.6 27.0 172.6 36.0 14.1 11.5 16.9 39.9 68.6 12.0 28.9 22.3 11.8 33.3 66.3 20.4 76.6 31.2 41.2 25.0 56.0 24.6 11.6 13.8 55.8 90.9 13.9 11.8 24.4 45.2 22.2 77.9 37.4 11.0 204.6 14.6 39.2 31.5 185.7 147.8 26.8 292.4 107.1 220.7 178.5 38.6 93.5 8.0 64.3 225.8 79.6 35.0 44.7 85.5 359.9 32.4 66.6 36.0 43.8 75.6 87.1 61.8 23.5 69.0 39.8 242.4 678.4 100.6 137.5 62.6 206.1 81.3 298.9 37.4 36.0 40.0 29.2 207.6 64.4 31.9 76.2 99.8 34.8 23.7 41.9 43.4 128.0 78.4 70.4 45.6 38.9 70.0 235.2 110.6 102.5 281.2 463.5 135.0 51.0 67.0 63.4 28.5 71.3 1.4 2.2 11.7 16.7 2.1 20.4 10.7 10.0 17.3 4.6 11.1 9.4 12.0 2.2 8.6 1.2 7.7 5.5 7.2 12.2 13.2 13.5 14.9 13.4 13.6 11.5 16.9 11.8 11.6 13.9 11.0 58.1 6.4 30.2 15.0 42.5 134.7 163.0 47.2 47.8 11.8 59.1 42.7 30.0 27.1 57.4 16.5 8.4 27.2 82.9 94.8 72.4 27.1 78.2 28.6 58.0 35.7 54.9 13.9 12.4 64.7 63.9 195.8 45.9 40.7 33.7 21.3 22.5 98.4 14.5 6.7 12.4 139.4 40.7 10.1 82.2 20.1 50.7 24.6 85.4 3.7 18.2 16.6 41.2 8.0 6.1 73.0 74.5 41.3 152.8 94.6 88.4 26.9 56.0 13.9 19.7 59.4 88.6 212.0 125.9 43.2 81.8 97.7 50.5 18.8 70.4 141.7 UBALD2 "FAM100B, MGC29814" ENSG00000185262 "UBA like domain containing 2" Q8IYN6 17 76265348-76271298 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 229.1" "Cell type enhanced" "Detected in all" "Urothelial cells: 205.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 7.8;neutrophil: 29.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 29.2" "Cell line enhanced" "Detected in all" "HDLM-2: 324.7;Karpas-707: 401.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023046 Uncertain NA Yes "Cluster 1: Neutrophils - Mixed function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "HPA023046: AB_1848359" "unprognostic (1.33e-1)" "unprognostic (2.04e-3)" "unprognostic (3.14e-1)" "unprognostic (3.06e-1)" "unprognostic (9.21e-2)" "unprognostic (1.74e-1)" "unprognostic (3.22e-3)" "unprognostic (5.06e-3)" "unprognostic (1.15e-1)" "unprognostic (1.01e-1)" "unprognostic (2.50e-2)" "unprognostic (1.20e-1)" "unprognostic (4.80e-2)" "unprognostic (3.78e-2)" "unprognostic (9.24e-2)" "unprognostic (3.45e-3)" "unprognostic (1.45e-3)" 43.9 19.4 36.1 54.4 38.0 229.1 43.6 36.5 48.8 33.1 32.4 53.6 80.0 24.5 8.0 97.9 29.4 14.8 44.5 32.5 53.6 39.1 35.2 72.0 45.0 68.4 42.9 17.7 43.6 26.6 22.1 21.9 47.0 33.3 17.9 6.9 59.5 10.9 172.4 63.0 81.5 8.9 35.8 75.1 51.5 23.0 45.2 38.8 34.2 25.9 25.5 33.1 49.6 44.1 118.6 26.2 23.7 18.9 29.2 27.5 56.0 42.7 32.8 17.9 20.3 30.8 127.9 31.2 44.0 12.5 19.7 43.3 12.1 24.1 14.1 324.7 30.5 34.5 31.4 29.0 20.1 40.9 162.8 24.9 31.8 19.1 50.3 21.0 57.4 99.6 55.5 401.9 23.3 61.3 193.2 99.4 21.8 71.4 48.1 93.9 49.6 87.3 33.8 66.6 60.3 57.4 30.1 41.2 217.0 25.8 29.8 106.3 42.3 35.8 52.1 60.3 68.9 177.7 149.2 67.8 41.6 34.0 99.8 7.8 1.8 3.3 2.3 1.5 1.9 2.7 3.9 2.4 0.7 2.1 4.6 3.7 29.2 1.4 1.1 3.9 2.8 0.6 36.1 38.0 36.5 48.8 32.5 53.6 68.4 42.9 47.0 35.8 45.2 44.1 81.6 22.4 17.6 5.2 99.8 71.9 84.5 15.5 18.8 12.8 95.5 78.2 18.0 67.2 16.6 23.9 14.6 9.0 115.3 117.2 15.6 31.4 25.5 126.6 43.1 53.1 36.3 59.8 5.1 30.8 18.6 23.5 42.8 181.6 22.2 21.6 29.6 34.3 29.2 11.8 5.8 84.5 10.2 60.5 55.6 8.2 19.9 87.9 49.8 8.4 27.5 31.3 50.4 6.0 8.7 44.7 80.6 20.3 106.6 93.2 119.3 22.4 30.2 18.7 19.7 25.5 28.8 5.1 4.5 38.7 106.3 27.9 100.9 30.6 72.4 205.6 UBC ENSG00000150991 "Ubiquitin C" P0CG48 12 124911604-124917368 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000362, CAB005419, HPA041344, HPA049132" Supported NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" "CAB000362: AB_2301097, CAB005419: AB_2180553, HPA041344: AB_2677422, HPA049132: AB_2680646" "unprognostic (7.46e-2)" "unprognostic (1.37e-1)" "unprognostic (1.24e-1)" "unprognostic (8.64e-3)" "unprognostic (2.41e-2)" "unprognostic (7.38e-2)" "unprognostic (6.35e-3)" "unprognostic (7.60e-3)" "unprognostic (1.48e-2)" "unprognostic (2.46e-1)" "unprognostic (1.78e-1)" "unprognostic (3.17e-2)" "prognostic unfavorable (7.90e-7)" "unprognostic (6.69e-2)" "unprognostic (2.74e-1)" "unprognostic (5.64e-2)" "unprognostic (8.81e-2)" 1262.3 939.6 1151.9 699.3 1221.6 2805.5 941.4 1314.4 1635.4 1055.3 1295.5 931.6 571.9 960.0 987.6 1641.4 1095.1 1356.3 1277.9 1143.2 1267.5 983.6 1652.7 1070.8 833.5 1278.5 1215.6 819.4 921.7 653.3 512.9 826.4 1231.8 709.8 1060.9 974.0 1114.7 1136.4 3463.2 933.2 836.0 1278.4 1259.5 799.3 813.0 1257.7 1239.5 767.6 912.2 3177.8 993.4 1144.9 1183.7 1600.9 1407.8 1259.6 1043.5 863.8 2845.1 1769.8 692.9 1750.1 2130.8 1259.1 1229.6 1129.7 1747.7 1272.9 1410.4 2133.4 2042.1 1026.2 2048.8 3325.1 1075.2 1480.4 760.1 971.1 831.8 2017.2 2199.3 1404.5 844.9 2035.2 2538.3 1500.0 2283.6 1644.8 1630.2 510.6 897.8 1259.9 1467.1 1270.4 1300.6 1641.0 966.5 835.3 1520.0 781.7 970.6 1182.5 1719.0 2164.3 1216.6 891.7 1691.7 1928.1 1622.1 619.9 1653.3 931.5 2019.6 2766.8 792.8 1496.9 1103.8 1460.9 1819.8 1608.8 1490.2 779.7 1805.4 335.0 532.6 606.0 431.8 517.4 412.7 315.8 375.2 450.0 310.2 295.5 292.5 350.7 989.3 401.3 653.5 432.6 499.4 1022.5 1151.9 1221.6 1314.4 1635.4 1143.2 1267.5 1278.5 1215.6 1231.8 1259.5 1239.5 1600.9 2304.5 1451.9 1227.6 128.0 1287.0 1219.8 3858.3 4028.1 1915.7 618.9 843.1 1183.4 915.2 683.4 2496.6 660.3 333.6 841.0 1282.5 1499.3 892.1 1475.7 4437.0 1595.5 1062.5 1370.6 747.6 340.1 42.3 1128.2 1268.9 1662.4 1305.8 2615.6 911.9 698.7 637.9 442.9 1295.9 518.2 49.3 1067.2 1564.5 654.8 1858.6 4032.6 786.9 1668.6 1220.2 124.6 1728.7 1784.0 520.1 31.7 106.2 1334.3 1613.6 830.1 2420.4 1775.3 1850.8 1023.9 1700.8 1215.7 611.4 1695.6 2149.7 1135.2 429.9 1523.5 1048.6 1754.1 1980.7 752.4 845.9 2349.3 UBE2C UBCH10 ENSG00000175063 "Ubiquitin conjugating enzyme E2 C" O00762 20 45812576-45816957 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 78.5;lymphoid tissue: 113.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 129.6;Erythroid cells: 182.1;Extravillous trophoblasts: 449.1;Granulosa cells: 119.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 8.2" "Group enriched" "Detected in many" 5 "granulocytes: 2.1;NK-cells: 2.1;T-cells: 8.2" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 4.3;white matter: 11.4" "Low region specificity" "Detected in some" "CAB011464, HPA034569, CAB035990, HPA054975" Approved Approved "Plasma membrane,Cytosol" Yes Yes "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "CAB011464: AB_442965, CAB035990: , HPA034569: AB_2674226, HPA054975: AB_2682658" "unprognostic (1.45e-2)" "unprognostic (2.19e-1)" "unprognostic (1.06e-1)" "unprognostic (2.11e-3)" "unprognostic (2.54e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (6.24e-6)" "unprognostic (2.27e-3)" "unprognostic (2.59e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (6.91e-4)" "unprognostic (3.76e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.09e-1)" "unprognostic (3.61e-1)" "unprognostic (4.65e-2)" "unprognostic (2.68e-1)" 2.6 2.9 0.3 21.5 0.3 78.5 4.3 0.9 0.6 6.1 0.7 26.7 21.4 5.7 0.6 37.2 1.9 2.7 1.4 0.2 0.3 1.9 2.9 5.4 45.3 0.3 0.7 1.3 1.0 0.4 0.4 20.4 0.7 1.5 30.9 0.2 5.0 0.9 0.9 18.5 20.6 10.5 0.2 15.8 13.0 16.4 1.6 113.5 1.1 0.2 69.5 6.9 12.3 0.4 312.8 223.9 390.9 188.3 10.4 24.0 225.2 238.5 121.6 390.7 278.4 743.8 345.4 327.6 233.2 115.5 475.6 294.9 2.2 260.5 395.8 141.7 213.7 101.5 168.5 196.0 3.0 145.4 241.6 7.6 27.8 265.7 257.3 57.4 193.4 206.4 1.8 261.6 325.4 516.2 243.5 41.1 237.1 350.8 529.4 256.0 354.8 1.4 134.9 105.9 226.1 188.7 378.3 271.7 154.4 196.2 276.6 209.4 70.1 341.2 298.4 236.2 473.4 84.3 2.9 369.4 208.0 103.4 328.6 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.8 1.7 0.6 0.1 0.1 0.1 2.1 2.1 0.5 0.3 8.2 3.2 0.3 0.3 0.9 0.6 0.2 0.3 0.3 0.7 0.7 0.2 1.6 0.4 0.9 0.0 3.7 0.0 17.9 17.3 7.8 39.0 5.7 0.0 8.6 14.6 0.0 1.5 9.3 0.0 0.0 129.6 3.6 27.4 0.0 1.3 12.0 5.8 5.9 9.5 1.2 182.1 0.0 0.5 449.1 28.5 25.5 9.6 5.7 119.0 18.2 3.6 92.6 0.0 0.1 41.1 50.8 20.8 18.1 6.4 0.9 24.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.5 7.2 0.0 37.0 12.6 6.2 0.6 1.8 0.0 0.0 0.5 19.2 52.2 50.7 83.2 11.6 31.2 13.7 2.5 68.4 18.4 UBE2S E2-EPF ENSG00000108106 "Ubiquitin conjugating enzyme E2 S" Q16763 19 55399745-55407788 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 115.9;testis: 158.3" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 341.4;dendritic cells: 432.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015228, HPA057150" Approved Approved "Nucleoplasm,Plasma membrane" NA Yes "Cluster 37: B-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" Nucleoplasm "CAB015228: , HPA057150: AB_2683351" "unprognostic (2.79e-1)" "unprognostic (2.42e-1)" "unprognostic (2.57e-1)" "prognostic unfavorable (2.05e-4)" "unprognostic (9.54e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (8.00e-6)" "unprognostic (1.42e-3)" "unprognostic (2.32e-1)" "unprognostic (2.31e-1)" "unprognostic (8.08e-2)" "unprognostic (4.52e-2)" "prognostic unfavorable (8.16e-8)" "unprognostic (1.05e-1)" "unprognostic (9.51e-2)" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" 16.3 17.6 17.1 21.8 17.3 115.9 11.0 15.7 23.7 16.8 10.9 18.5 11.4 17.2 5.5 37.1 15.1 13.1 24.8 25.2 23.8 13.0 11.5 16.2 35.7 17.0 16.5 14.8 7.7 6.8 28.8 13.6 22.2 15.1 9.3 9.4 12.0 6.2 15.5 12.0 16.2 15.0 16.7 25.7 17.6 158.3 18.9 47.8 10.3 5.7 30.9 16.2 17.8 21.3 532.9 279.4 241.3 193.8 15.3 21.6 42.9 419.3 126.1 253.2 229.1 191.1 183.6 508.6 169.5 106.4 304.5 152.9 243.6 109.5 111.4 402.0 810.5 305.8 162.8 62.5 45.1 370.0 286.0 23.8 30.2 186.7 179.1 55.0 100.6 272.7 310.0 347.0 161.3 139.5 503.2 191.3 605.3 147.2 470.6 437.4 185.5 185.8 69.2 111.5 609.3 330.0 534.5 131.2 248.6 72.6 93.8 198.1 155.9 151.9 432.8 130.7 1013.5 277.1 734.4 617.0 159.2 257.5 562.7 0.5 0.8 1.3 0.7 0.6 0.5 2.5 1.0 1.0 0.6 0.6 1.0 0.5 2.4 0.2 0.4 1.3 0.4 0.1 17.1 17.3 15.7 23.7 25.2 23.8 17.0 16.5 22.2 16.7 18.9 21.3 308.0 0.0 3.4 5.9 161.3 162.6 151.2 31.5 81.4 59.3 235.9 341.4 3.1 8.6 9.9 20.2 54.2 87.8 432.7 59.2 15.6 42.8 127.5 89.3 68.2 72.5 92.6 166.5 8.7 30.5 247.9 99.3 44.9 68.0 18.4 200.9 31.8 10.6 65.5 32.0 11.0 69.1 38.7 26.8 125.3 52.2 17.4 131.7 74.7 3.7 36.7 91.1 21.6 7.5 13.5 82.3 44.1 12.4 100.6 82.9 20.4 18.4 9.7 75.7 13.1 125.2 186.7 196.9 174.0 74.1 115.9 59.8 233.3 64.6 55.8 121.1 UBE2T "FANCT, HSPC150" ENSG00000077152 "Ubiquitin conjugating enzyme E2 T" Q9NPD8 1 202331657-202341980 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 47.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 74.5;Erythroid cells: 134.3;Extravillous trophoblasts: 103.4;Spermatocytes: 114.1;Spermatogonia: 113.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002831 Approved Nucleoplasm,Nucleoli NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoli Nucleoplasm "HPA002831: AB_1080445" "unprognostic (2.38e-3)" "unprognostic (6.37e-2)" "unprognostic (5.27e-2)" "unprognostic (5.19e-2)" "unprognostic (2.81e-1)" "unprognostic (6.13e-3)" "prognostic unfavorable (4.79e-6)" "unprognostic (1.71e-2)" "unprognostic (2.32e-2)" "prognostic favorable (6.90e-6)" "unprognostic (6.28e-3)" "unprognostic (2.85e-2)" "prognostic unfavorable (2.22e-16)" "unprognostic (5.37e-3)" "unprognostic (1.58e-1)" "unprognostic (1.20e-1)" "unprognostic (4.86e-2)" 2.3 3.7 6.6 10.4 6.5 28.7 4.5 5.8 13.7 4.1 5.0 13.1 8.7 4.5 4.4 10.6 3.3 2.5 11.3 6.8 7.4 3.5 3.2 3.0 19.0 6.5 6.6 1.0 0.7 4.4 3.0 10.1 6.9 2.1 15.5 2.5 2.7 3.1 17.2 5.3 8.2 9.4 6.0 6.2 4.7 19.3 6.7 47.1 2.9 13.0 18.6 6.3 5.0 6.1 123.3 111.6 167.1 79.8 15.4 27.9 94.2 130.2 72.8 146.0 102.6 79.9 147.1 140.4 50.0 47.0 108.4 98.6 154.1 76.7 131.2 128.1 87.2 85.6 54.0 93.8 6.9 105.2 102.0 9.8 18.1 114.0 47.2 34.3 85.8 157.4 111.0 114.0 116.4 113.3 190.8 135.1 65.4 126.9 57.4 145.0 176.2 122.9 57.1 58.1 131.3 132.8 90.2 112.1 44.8 49.8 117.1 64.6 41.8 65.7 104.6 116.1 159.6 57.8 120.1 182.9 64.5 107.0 139.1 0.0 0.7 1.7 3.3 2.3 2.5 8.5 4.5 3.3 1.7 6.6 6.4 7.1 0.0 1.2 8.9 3.4 10.8 2.4 6.6 6.5 5.8 13.7 6.8 7.4 6.5 6.6 6.9 6.0 6.7 6.1 1.9 0.0 2.2 1.3 13.3 14.3 10.4 29.9 2.8 6.4 6.3 8.6 12.8 0.0 12.1 5.5 0.0 74.5 5.4 10.1 5.9 10.9 24.4 15.7 7.6 5.3 1.2 134.3 8.3 7.5 103.4 11.8 10.7 6.7 8.8 32.2 3.9 2.4 27.7 10.1 6.1 14.4 32.6 1.9 5.4 8.2 3.1 5.8 3.6 1.9 2.6 1.6 0.0 1.0 1.4 10.3 2.9 4.1 32.1 5.2 3.3 12.2 16.2 1.2 6.6 0.8 11.3 114.1 113.1 15.5 10.9 22.4 9.3 12.1 30.5 11.3 UHRF1 "FLJ21925, ICBP90, Np95, RNF106, TDRD22" ENSG00000276043 "Ubiquitin like with PHD and ring finger domains 1" Q96T88 19 4903080-4962154 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, DNA-binding, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 27.0;lymphoid tissue: 67.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 49.7;Plasma cells: 21.0;Squamous epithelial cells: 15.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.8" "Group enriched" "Detected in many" 4 "dendritic cells: 4.8;T-cells: 2.3" "Cell line enhanced" "Detected in all" "MOLT-4: 450.9;REH: 1004.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA049408, HPA055446" Enhanced Supported Nucleoplasm No Yes "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA049408: AB_2756317, HPA055446: AB_2732597" "unprognostic (3.83e-2)" "unprognostic (6.83e-3)" "unprognostic (5.13e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "unprognostic (7.21e-2)" "prognostic unfavorable (1.63e-4)" "unprognostic (4.30e-2)" "prognostic unfavorable (6.81e-4)" "unprognostic (2.82e-1)" "prognostic unfavorable (4.52e-5)" "unprognostic (2.33e-3)" "unprognostic (0.00e+0)" "unprognostic (3.75e-3)" "unprognostic (2.45e-1)" "unprognostic (2.01e-1)" "unprognostic (2.02e-1)" 1.0 0.9 2.1 9.6 2.7 27.0 1.7 2.1 2.3 1.6 1.8 2.9 3.7 1.0 0.1 6.5 0.4 0.8 0.5 2.0 2.2 0.6 0.9 1.3 15.8 2.8 2.8 0.3 0.6 0.2 0.2 2.1 2.7 0.6 2.6 0.4 1.5 0.2 1.2 3.4 3.9 1.9 1.9 3.7 3.3 5.2 3.5 67.2 0.3 0.3 10.3 1.6 2.5 4.6 111.3 78.7 116.6 83.4 3.3 13.3 18.5 88.3 42.0 89.9 86.8 94.6 54.9 62.7 21.1 39.4 32.7 54.1 81.2 47.7 63.0 102.7 92.2 54.3 74.3 102.4 1.3 135.1 78.9 6.5 3.5 48.9 12.6 14.1 27.2 97.2 79.3 70.5 54.5 86.7 450.9 82.5 52.5 40.0 84.3 1004.5 259.7 45.4 24.9 80.1 86.0 68.5 69.2 37.7 12.1 18.8 68.2 127.6 34.2 94.6 76.7 124.3 108.3 29.8 33.1 183.5 54.8 129.7 123.3 0.3 0.2 0.1 0.6 0.0 0.0 0.2 0.8 1.0 1.3 0.1 0.2 0.8 0.8 0.5 0.2 4.8 2.3 0.6 2.1 2.7 2.1 2.3 2.0 2.2 2.8 2.8 2.7 1.9 3.5 4.6 0.2 0.0 0.0 1.6 2.1 0.0 0.8 0.0 3.4 2.5 4.4 2.8 4.3 1.5 0.6 0.0 0.0 6.6 6.9 2.6 0.0 2.2 2.9 1.3 1.8 2.2 0.0 49.7 0.4 0.4 7.8 4.7 8.6 2.4 0.0 10.4 0.4 0.7 8.9 3.3 0.4 2.3 0.0 1.9 0.0 1.8 0.6 3.8 0.0 0.0 2.0 0.6 1.0 3.0 1.3 4.2 1.9 0.4 21.0 0.6 1.4 0.2 0.7 0.7 0.0 1.2 6.1 6.1 11.9 15.8 0.0 1.4 3.7 1.5 8.3 1.3 UNG "DGU, HIGM4, UDG, UNG1, UNG2" ENSG00000076248 "Uracil DNA glycosylase" P13051 12 109097597-109110992 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 64.9;Spermatogonia: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB011605 Uncertain Approved Cytosol NA Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "CAB011605: AB_778737" "unprognostic (4.38e-2)" "unprognostic (3.82e-3)" "unprognostic (1.03e-2)" "unprognostic (1.33e-2)" "unprognostic (4.64e-1)" "unprognostic (4.10e-2)" "prognostic unfavorable (6.40e-4)" "unprognostic (5.68e-3)" "prognostic unfavorable (3.06e-4)" "unprognostic (4.66e-2)" "unprognostic (8.78e-3)" "unprognostic (1.91e-1)" "unprognostic (1.35e-3)" "unprognostic (2.57e-2)" "unprognostic (4.50e-1)" "unprognostic (1.40e-2)" "unprognostic (6.89e-2)" 19.8 56.7 32.4 14.7 32.4 16.0 23.1 30.1 34.8 16.6 27.7 28.0 17.1 14.5 12.7 29.7 15.6 10.4 21.1 29.2 34.9 27.5 32.2 9.6 18.0 32.2 31.4 15.7 12.4 33.2 10.9 17.8 34.1 13.6 29.3 6.8 17.7 17.6 43.0 32.7 18.8 14.5 31.6 16.1 17.7 24.3 33.5 22.8 22.2 33.5 27.0 13.5 20.1 30.8 77.1 77.5 72.8 66.6 118.6 33.8 69.5 44.4 30.1 68.6 52.3 61.7 51.6 100.3 65.1 40.2 35.9 47.6 81.4 46.0 66.4 85.6 150.9 98.1 41.1 105.5 17.7 147.6 58.2 30.7 41.6 33.0 18.3 54.6 50.4 117.8 80.9 32.5 47.0 96.2 136.8 173.6 130.0 124.2 117.7 123.9 109.8 85.9 43.4 95.6 103.3 57.4 79.6 67.8 39.5 94.2 126.2 68.2 26.0 59.1 52.7 39.3 62.5 62.6 145.0 190.5 44.8 97.7 73.8 12.9 2.7 5.0 22.4 5.3 31.6 16.0 25.5 25.6 6.8 17.2 16.4 18.4 0.0 16.5 5.5 4.9 25.5 14.4 32.4 32.4 30.1 34.8 29.2 34.9 32.2 31.4 34.1 31.6 33.5 30.8 26.6 0.0 4.8 16.0 9.2 18.0 11.0 13.2 25.0 2.6 21.7 14.1 12.4 7.2 5.0 42.3 4.2 64.9 12.5 14.7 19.6 14.4 3.4 7.6 15.0 17.7 8.4 32.4 7.0 6.2 38.1 12.6 14.3 9.9 7.6 24.8 20.3 20.8 18.3 5.0 6.2 21.4 10.2 3.8 5.4 4.2 14.0 5.5 14.2 6.5 3.8 15.8 7.2 6.6 4.0 5.0 10.3 14.7 16.7 6.8 9.3 20.2 3.2 3.5 6.6 10.2 11.5 21.9 74.6 37.8 20.9 20.4 15.3 25.7 40.4 9.7 USP37 KIAA1594 ENSG00000135913 "Ubiquitin specific peptidase 37" Q86T82 2 218450251-218568351 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 119.4;Late spermatids: 145.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045160 Approved Approved Nucleoplasm,Nucleoli NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Nucleoli" "HPA045160: AB_10795620" "unprognostic (7.00e-2)" "unprognostic (2.29e-1)" "unprognostic (8.83e-2)" "unprognostic (9.19e-4)" "unprognostic (1.83e-1)" "prognostic favorable (2.85e-4)" "unprognostic (2.18e-2)" "unprognostic (1.14e-1)" "unprognostic (9.66e-3)" "unprognostic (1.17e-1)" "unprognostic (3.78e-3)" "unprognostic (1.11e-1)" "unprognostic (3.82e-2)" "unprognostic (3.26e-1)" "unprognostic (2.87e-1)" "unprognostic (6.69e-2)" "unprognostic (6.41e-3)" 2.7 4.1 3.5 4.4 4.7 11.8 4.7 8.5 4.9 3.6 1.9 3.0 2.9 4.2 7.5 3.9 3.3 3.5 2.3 3.3 4.0 2.9 3.8 3.0 6.0 3.8 4.0 5.9 3.0 4.0 1.4 4.0 4.0 3.6 3.5 9.1 3.9 3.0 2.9 3.9 3.3 3.2 2.5 3.8 3.4 12.7 3.4 6.3 5.0 4.2 4.9 3.6 2.2 8.3 9.6 6.9 14.2 11.0 3.6 4.4 12.1 7.1 5.1 12.2 13.6 13.1 7.4 8.7 7.5 5.6 9.3 8.9 15.7 8.0 13.4 12.0 8.3 23.5 13.6 8.7 4.1 15.6 11.3 2.4 4.7 12.9 9.2 4.5 5.3 15.0 17.3 16.2 7.8 7.2 20.1 10.6 12.2 6.2 5.9 16.0 21.3 8.0 4.2 11.2 15.5 8.4 11.5 5.6 7.2 13.6 6.4 10.8 6.8 13.7 12.0 7.7 9.5 11.0 10.4 17.6 7.4 11.2 9.5 4.2 2.0 3.8 3.1 2.3 3.2 2.5 2.6 2.7 2.1 3.2 4.0 2.6 1.6 3.2 2.2 2.9 3.6 1.2 3.5 4.7 8.5 4.9 3.3 4.0 3.8 4.0 4.0 2.5 3.4 8.3 12.8 0.0 11.0 34.3 16.5 19.5 7.0 7.1 22.2 14.7 14.4 10.2 4.9 4.3 9.6 7.3 27.1 8.4 13.4 5.5 0.0 5.8 119.4 13.3 11.8 14.2 10.3 16.6 47.4 2.3 6.6 13.2 9.2 16.4 5.1 16.2 12.5 11.0 7.8 15.2 40.0 8.9 4.1 8.5 22.9 145.5 9.9 17.2 21.4 27.2 10.2 9.1 10.3 35.2 60.5 4.9 7.4 9.8 14.6 12.1 7.1 4.2 11.1 19.9 6.6 12.7 21.6 60.8 31.4 13.6 20.6 7.3 19.7 10.9 7.6 7.1 VANGL1 STB2 ENSG00000173218 "VANGL planar cell polarity protein 1" Q8TAA9 1 115641970-115698224 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 39.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "NK-cell: 6.2" "Group enriched" "Detected in many" 7 "dendritic cells: 2.3;NK-cells: 6.2;T-cells: 3.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025235, CAB076375" Approved Approved "Plasma membrane" NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB076375: AB_2665604, HPA025235: AB_1858718" "unprognostic (1.04e-2)" "unprognostic (2.04e-2)" "prognostic favorable (7.53e-4)" "unprognostic (9.94e-2)" "unprognostic (1.71e-2)" "unprognostic (5.18e-2)" "unprognostic (2.18e-3)" "unprognostic (5.11e-3)" "unprognostic (2.11e-1)" "unprognostic (6.43e-3)" "prognostic unfavorable (7.89e-4)" "unprognostic (1.88e-2)" "unprognostic (1.74e-2)" "unprognostic (7.71e-3)" "unprognostic (1.21e-1)" "unprognostic (4.50e-3)" "unprognostic (9.06e-3)" 4.9 3.9 2.1 3.8 1.2 2.5 3.2 0.8 1.1 9.1 3.0 6.8 3.8 5.5 4.9 10.4 12.0 3.8 5.4 1.3 1.3 5.3 3.0 4.1 2.1 1.2 3.0 4.4 5.0 5.2 0.5 3.6 1.7 4.4 6.4 1.6 6.4 4.5 0.9 6.8 3.9 7.3 1.2 2.2 5.5 5.0 6.5 7.3 7.6 2.4 2.5 6.4 4.4 1.0 49.6 20.7 6.6 8.9 24.1 21.5 13.1 18.8 13.5 24.1 19.1 12.0 24.1 0.0 31.5 21.9 22.7 60.9 11.2 33.3 15.8 57.9 13.7 27.4 18.4 9.8 8.8 8.2 11.4 11.4 23.1 17.2 18.2 12.8 24.1 45.9 16.8 14.8 24.5 65.7 41.0 3.4 16.7 28.8 19.5 0.1 19.1 14.3 11.0 32.8 5.9 8.0 33.9 22.2 15.4 12.4 11.3 8.8 26.2 16.5 25.7 36.3 34.6 2.1 2.3 0.2 22.3 14.3 41.1 0.0 0.5 0.0 1.9 0.3 0.5 0.2 1.2 1.9 2.3 0.0 0.4 2.0 0.0 6.2 0.5 2.0 3.0 1.0 2.1 1.2 0.8 1.1 1.3 1.3 1.2 3.0 1.7 1.2 6.5 1.0 9.2 3.2 3.2 5.5 0.5 7.4 7.4 16.8 11.4 5.2 4.6 4.6 7.9 2.8 9.6 9.2 39.6 5.0 3.4 11.2 0.0 15.7 6.1 25.1 7.7 10.5 6.7 13.2 0.9 13.8 7.3 10.1 8.2 17.0 0.0 5.1 28.9 2.5 4.3 0.0 0.7 8.6 10.2 1.9 1.4 3.0 5.9 2.9 0.0 4.7 11.1 4.7 9.2 2.0 0.1 20.8 6.1 8.2 1.8 8.3 2.6 5.6 12.8 0.9 6.6 4.3 8.5 5.5 7.0 20.0 6.5 0.4 3.1 3.2 10.3 6.5 VASN SLITL2 ENSG00000168140 Vasorin Q6EMK4 16 4371848-4383538 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 58.7;Fibroblasts: 104.2;Leydig cells: 50.1;Peritubular cells: 60.9;Sertoli cells: 98.6;Smooth muscle cells: 80.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 21.8;MCF7: 18.4;U-2197: 78.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011246, HPA016992" Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria "Secreted - unknown location" NA Yes 2000000000 "Cluster 72: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria "Nucleoplasm, Nucleoli" "HPA011246: AB_1858720, HPA016992: AB_2732418" "unprognostic (2.20e-1)" "unprognostic (2.75e-1)" "unprognostic (9.22e-2)" "prognostic unfavorable (6.24e-5)" "unprognostic (2.35e-3)" "unprognostic (8.91e-3)" "unprognostic (3.15e-3)" "unprognostic (5.92e-2)" "unprognostic (2.22e-1)" "unprognostic (1.24e-2)" "unprognostic (1.08e-1)" "unprognostic (1.28e-1)" "unprognostic (1.81e-1)" "unprognostic (8.82e-3)" "unprognostic (4.23e-2)" "unprognostic (4.95e-3)" "unprognostic (5.27e-2)" 55.7 15.5 1.5 5.8 2.3 2.7 31.5 0.8 2.3 48.1 3.0 12.1 3.4 30.3 0.0 34.1 24.6 7.3 30.5 1.1 0.5 56.1 31.8 44.9 2.8 6.3 5.5 40.0 10.3 0.0 12.8 10.4 1.7 17.9 0.0 0.3 15.9 0.0 6.9 38.8 11.2 0.0 1.6 13.0 13.4 16.8 4.6 0.0 26.8 0.0 0.0 26.5 38.9 2.7 4.2 0.0 0.6 0.5 0.2 0.2 12.6 21.8 0.1 0.0 0.0 1.9 5.5 0.0 4.5 0.3 2.6 0.3 0.0 0.0 0.0 13.7 2.2 0.9 15.9 14.9 0.6 0.0 0.4 7.9 0.0 0.3 0.0 3.1 0.0 0.1 3.1 0.8 0.0 18.4 1.0 5.3 2.2 0.4 2.4 1.0 0.0 0.0 0.0 0.1 1.4 9.3 6.5 13.5 0.6 2.2 6.8 2.5 0.0 17.5 12.5 78.4 4.6 0.0 0.0 0.3 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.3 0.8 2.3 1.1 0.5 6.3 5.5 1.7 1.6 4.6 2.7 10.0 6.4 13.1 5.5 1.4 9.6 7.8 4.2 9.1 0.5 21.9 10.9 16.2 32.9 6.4 23.9 0.0 5.4 2.8 1.5 7.9 13.1 1.1 12.1 58.7 4.6 0.0 0.0 1.1 2.9 7.2 104.2 16.8 20.5 3.8 4.6 2.9 15.3 3.4 0.0 0.9 2.0 2.0 0.6 21.7 2.8 50.1 2.0 14.2 2.8 0.0 18.3 0.0 0.5 0.3 28.3 1.2 60.9 0.8 6.4 0.2 12.3 2.7 0.7 98.6 12.6 80.9 0.8 4.1 3.7 7.5 10.0 3.5 2.3 0.8 4.9 VPS25 "DERP9, EAP20, MGC10540" ENSG00000131475 "Vacuolar protein sorting 25 homolog" Q9BRG1 17 42773449-42779599 "Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004978, HPA021992, HPA052217, HPA057284" Uncertain Supported Vesicles NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB004978: AB_426095, HPA021992: , HPA052217: AB_2681765, HPA057284: AB_2683397" "unprognostic (3.63e-2)" "unprognostic (1.47e-1)" "prognostic favorable (3.18e-4)" "unprognostic (7.37e-2)" "unprognostic (7.57e-2)" "unprognostic (9.83e-3)" "unprognostic (2.76e-3)" "unprognostic (5.84e-2)" "unprognostic (1.25e-1)" "unprognostic (2.90e-1)" "unprognostic (8.10e-3)" "unprognostic (3.88e-1)" "unprognostic (2.39e-3)" "unprognostic (1.15e-1)" "unprognostic (1.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.91e-2)" 36.6 40.3 32.8 32.5 33.0 44.3 53.3 34.8 36.8 41.6 36.6 61.9 53.8 35.5 65.3 91.4 58.9 33.4 43.5 32.9 33.2 70.1 68.6 31.8 37.8 32.9 32.8 33.2 49.0 72.3 27.6 46.7 33.5 40.2 68.4 31.2 48.7 36.5 51.3 50.5 45.4 42.8 33.5 37.1 50.0 27.4 33.8 51.3 40.9 41.3 57.2 44.8 44.3 34.0 67.2 136.6 101.8 62.1 126.9 86.5 94.5 83.0 117.1 167.5 116.3 117.9 77.0 66.8 135.8 122.0 88.5 68.7 142.2 181.8 107.9 61.2 178.7 50.6 87.0 177.5 131.0 95.7 64.6 118.2 115.4 148.9 158.0 99.1 106.7 79.0 175.6 65.5 102.1 96.5 138.8 105.2 78.9 152.0 95.3 51.1 123.3 108.7 202.6 75.8 86.3 66.7 46.8 60.1 129.6 155.8 138.4 100.2 58.0 105.7 68.4 60.0 90.3 64.0 39.4 97.9 92.7 64.5 79.6 85.1 76.9 106.7 38.8 89.0 39.9 48.8 42.4 46.4 80.3 46.6 42.3 40.7 44.9 78.9 82.7 54.1 43.1 59.6 32.8 33.0 34.8 36.8 32.9 33.2 32.9 32.8 33.5 33.5 33.8 34.0 26.3 25.6 36.3 4.2 25.3 13.9 41.0 88.3 16.5 24.1 44.4 46.6 26.9 51.5 65.7 62.5 14.6 136.1 22.0 74.3 133.1 135.9 2.6 61.8 48.5 35.4 41.0 47.9 3.5 152.4 186.5 40.8 40.8 55.9 29.2 21.5 29.6 46.4 102.3 23.5 3.5 70.5 85.5 34.5 12.7 5.6 27.7 33.0 42.7 0.0 46.7 56.1 44.3 2.5 4.7 134.4 75.7 30.5 40.9 44.4 83.5 93.6 74.9 29.5 32.9 13.5 69.9 42.8 46.7 61.9 22.9 121.6 22.8 69.9 63.4 53.5 WDHD1 "AND-1, CHTF4, CTF4" ENSG00000198554 "WD repeat and HMG-box DNA binding protein 1" O75717 14 54938949-55027105 "Predicted intracellular proteins, Predicted membrane proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 15.5;Spermatocytes: 15.0;Spermatogonia: 19.3" "Cancer enhanced" "Detected in all" "testis cancer: 23.5" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000632, HPA001122" Enhanced Enhanced Nucleoplasm NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA000632: , HPA001122: AB_1080589" "unprognostic (1.88e-1)" "unprognostic (1.21e-1)" "unprognostic (1.98e-2)" "unprognostic (2.25e-3)" "unprognostic (1.20e-1)" "unprognostic (6.85e-3)" "unprognostic (2.33e-4)" "unprognostic (5.52e-3)" "unprognostic (7.28e-3)" "unprognostic (8.05e-3)" "prognostic unfavorable (9.24e-4)" "unprognostic (5.11e-2)" "unprognostic (2.67e-4)" "unprognostic (8.31e-3)" "unprognostic (1.50e-1)" "unprognostic (3.49e-2)" "unprognostic (2.36e-2)" 1.3 0.8 0.5 3.8 1.0 7.2 2.2 0.9 0.9 1.2 0.1 2.8 1.8 2.1 0.6 2.4 1.6 1.3 0.9 0.7 0.2 1.1 1.2 1.3 5.5 0.2 0.2 1.4 0.9 1.5 0.3 2.8 0.2 1.0 4.0 1.8 0.7 0.8 0.6 2.0 1.7 2.6 0.3 1.7 1.6 5.3 0.4 8.0 0.9 0.8 6.7 1.7 1.1 0.9 39.6 24.7 48.4 21.4 4.6 11.2 28.1 37.5 16.1 29.6 36.0 16.6 25.9 44.9 18.6 10.8 21.4 32.8 72.9 21.5 61.7 30.0 12.7 29.8 23.7 16.2 1.9 56.7 21.8 5.9 3.8 36.6 14.3 7.1 19.6 28.8 37.8 22.0 28.7 21.7 53.5 11.1 38.6 21.1 25.7 49.5 69.7 17.3 8.4 26.0 28.1 19.8 39.8 10.0 12.8 35.1 26.8 11.3 12.8 37.3 43.9 27.5 32.1 6.5 14.4 58.8 17.1 27.4 30.0 1.7 0.3 0.6 0.9 0.2 1.2 1.2 1.0 1.3 0.5 1.8 1.3 1.8 0.4 2.0 0.4 0.7 1.6 0.6 0.5 1.0 0.9 0.9 0.7 0.2 0.2 0.2 0.2 0.3 0.4 0.9 2.3 0.0 2.0 3.9 5.1 3.8 2.2 3.5 3.4 2.9 1.8 1.9 1.7 0.0 4.0 3.7 0.0 8.7 3.6 1.8 0.0 1.8 0.8 1.9 3.1 2.0 0.0 15.5 10.3 1.0 8.4 3.4 2.6 2.5 0.0 12.4 0.7 0.9 4.1 3.3 6.5 2.4 6.1 2.1 1.2 1.1 0.0 2.4 1.8 5.6 1.4 1.4 2.1 4.5 10.1 1.1 0.3 3.0 7.8 0.6 0.5 6.2 3.5 3.1 0.0 2.4 3.0 15.0 19.3 6.1 2.4 2.6 3.6 2.8 5.2 1.7 WDR76 FLJ12973 ENSG00000092470 "WD repeat domain 76" Q9H967 15 43826980-43868412 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.1;lymphoid tissue: 21.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 35.3;Spermatocytes: 23.5;Spermatogonia: 35.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039804, HPA040626" Uncertain Approved "Nucleoli fibrillar center,Nuclear bodies" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies" "Nucleoli fibrillar center" "HPA039804: AB_10795297, HPA040626: AB_10795527" "unprognostic (2.26e-1)" "unprognostic (7.56e-3)" "unprognostic (7.05e-2)" "unprognostic (1.88e-1)" "unprognostic (5.85e-2)" "unprognostic (3.12e-2)" "prognostic unfavorable (6.98e-4)" "prognostic unfavorable (8.02e-5)" "unprognostic (4.24e-3)" "unprognostic (6.25e-2)" "prognostic unfavorable (5.02e-4)" "unprognostic (1.91e-2)" "prognostic unfavorable (1.35e-8)" "unprognostic (7.71e-2)" "unprognostic (9.42e-2)" "unprognostic (4.02e-2)" "unprognostic (3.28e-2)" 2.6 1.2 1.0 8.4 1.1 19.1 3.5 4.8 1.7 3.0 0.8 4.8 3.2 3.3 0.9 4.5 1.7 1.9 1.1 0.7 1.1 1.5 2.2 2.4 19.8 1.3 1.1 2.2 3.1 2.7 1.1 3.9 1.3 1.9 6.0 6.3 2.4 2.0 0.8 4.1 3.3 3.9 1.0 3.6 2.9 5.3 1.3 19.5 2.5 1.3 21.3 2.8 2.8 1.2 35.1 17.5 40.7 31.3 4.5 10.7 11.1 57.3 33.9 61.5 76.8 22.1 17.8 51.4 24.8 26.9 31.0 49.4 42.4 20.5 53.1 80.4 25.2 63.3 52.1 7.3 2.5 65.0 27.0 3.4 3.3 33.8 7.7 8.9 19.9 54.7 48.6 86.9 42.6 12.2 63.4 15.4 14.6 11.0 18.1 66.9 70.1 32.4 11.4 35.5 31.3 30.9 36.1 22.5 7.0 12.6 35.0 31.0 9.1 56.3 26.5 63.5 58.9 42.7 114.6 129.1 40.4 56.7 31.5 0.0 0.6 0.3 3.8 0.5 4.1 1.8 4.6 3.4 1.0 2.2 3.8 2.9 0.0 4.8 0.2 1.2 6.6 2.0 1.0 1.1 4.8 1.7 0.7 1.1 1.3 1.1 1.3 1.0 1.3 1.2 4.1 3.2 1.3 2.6 8.2 7.4 3.2 2.4 4.6 3.7 3.7 2.8 1.2 1.5 2.3 1.8 10.4 12.8 6.2 3.5 1.9 2.9 1.7 1.8 3.9 4.8 0.0 35.3 2.5 4.2 13.0 3.9 4.6 3.3 5.7 12.2 2.9 0.9 8.9 1.7 3.3 3.7 0.0 3.5 5.3 0.9 1.8 3.9 3.6 2.8 3.3 8.0 10.3 0.5 1.9 1.1 3.1 2.2 16.1 1.5 1.4 0.9 0.4 16.2 6.6 5.8 5.7 23.5 35.9 7.4 5.8 3.6 11.6 1.5 9.0 1.8 WSB1 "DKFZp564A122, DKFZp564B0482, SWIP1" ENSG00000109046 "WD repeat and SOCS box containing 1" Q9Y6I7 17 27294076-27315926 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003293 Approved Approved Mitochondria NA Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 41: Macrophages - Immune response" Mitochondria "HPA003293: AB_1858863" "unprognostic (1.73e-1)" "unprognostic (5.13e-2)" "unprognostic (1.25e-1)" "unprognostic (1.44e-1)" "unprognostic (2.14e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (4.07e-5)" "unprognostic (2.59e-2)" "unprognostic (5.40e-3)" "unprognostic (2.74e-1)" "unprognostic (9.22e-2)" "unprognostic (1.69e-2)" "prognostic unfavorable (1.02e-7)" "unprognostic (1.44e-1)" "unprognostic (3.18e-1)" "unprognostic (1.62e-1)" "unprognostic (3.74e-2)" 41.9 22.1 14.1 45.9 35.7 48.7 35.7 22.9 26.9 47.0 5.2 40.7 28.6 49.4 24.6 27.7 45.9 39.6 32.5 14.1 35.9 29.0 15.6 58.3 34.5 38.7 22.7 47.7 29.6 19.0 23.8 75.0 40.6 27.6 30.9 76.0 27.4 32.1 23.0 23.2 33.7 44.8 17.0 69.9 32.7 21.6 33.2 24.8 28.8 16.1 35.2 32.8 39.1 80.0 30.8 21.3 65.3 37.5 40.3 49.7 69.7 26.6 37.9 20.6 39.6 32.0 12.2 30.6 29.6 36.6 26.2 28.4 40.0 19.6 30.9 85.3 33.1 48.7 41.9 32.7 75.7 34.1 69.2 60.2 26.3 30.1 18.4 31.5 83.1 31.7 49.8 28.6 36.9 19.4 44.4 38.4 19.4 17.1 17.3 35.5 35.9 18.5 31.1 24.6 20.9 28.8 27.8 27.3 36.7 77.8 22.1 44.5 46.5 25.3 19.2 34.8 26.4 12.8 34.9 31.2 23.9 26.8 23.4 75.0 41.1 71.5 21.6 70.3 26.1 22.1 18.1 24.2 65.5 25.3 17.0 19.7 37.1 21.4 82.5 21.5 30.2 26.4 14.1 35.7 22.9 26.9 14.1 35.9 38.7 22.7 40.6 17.0 33.2 80.0 300.4 221.2 476.1 189.7 245.4 249.2 185.6 138.4 253.8 91.9 186.7 147.7 67.5 144.4 194.2 239.1 348.2 360.7 183.2 222.7 27.4 124.9 153.0 201.2 187.6 254.9 194.4 148.1 229.5 65.1 217.2 284.6 190.6 301.5 163.5 436.3 316.6 43.3 228.2 82.4 267.8 191.5 162.8 412.6 288.9 26.6 141.4 358.9 197.5 206.1 153.2 170.5 112.3 349.3 658.2 76.7 185.4 122.6 144.9 196.3 178.7 30.7 137.5 381.4 124.9 243.8 221.9 119.6 104.8 202.2 280.3 714.5 183.9 98.5 133.6 148.9 ZC3H15 LEREPO4 ENSG00000065548 "Zinc finger CCCH-type containing 15" Q8WU90 2 186486253-186509361 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031099, HPA031100, HPA031101" Enhanced Enhanced Cytosol NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Cytosol "HPA031099: AB_10599418, HPA031100: AB_2257403, HPA031101: AB_10611669" "unprognostic (1.51e-1)" "prognostic unfavorable (6.45e-5)" "unprognostic (2.24e-1)" "unprognostic (3.11e-3)" "unprognostic (5.92e-2)" "unprognostic (8.15e-2)" "prognostic unfavorable (1.48e-7)" "unprognostic (9.08e-3)" "unprognostic (4.95e-2)" "prognostic favorable (3.98e-4)" "prognostic unfavorable (9.75e-4)" "unprognostic (5.72e-3)" "unprognostic (5.69e-2)" "unprognostic (1.87e-1)" "unprognostic (1.82e-1)" "unprognostic (8.89e-2)" "unprognostic (3.45e-2)" 42.6 47.5 39.2 44.3 42.0 128.8 45.9 43.4 52.5 35.1 38.6 40.8 48.3 39.8 47.0 40.2 26.3 36.5 37.0 42.6 44.5 53.8 67.3 28.4 53.9 42.2 40.9 32.6 47.9 41.2 27.2 48.8 41.7 37.0 46.0 53.0 45.3 32.4 50.3 44.3 46.1 36.9 39.4 38.6 36.8 40.6 41.7 50.2 49.3 44.9 51.4 54.0 29.2 42.4 103.5 68.9 83.3 107.8 93.0 93.4 124.9 112.7 76.7 102.3 91.5 202.9 81.8 140.3 100.2 80.9 130.9 73.6 155.8 137.5 144.0 128.7 118.1 201.9 101.1 221.9 124.9 208.7 118.6 77.2 149.6 111.4 157.2 89.9 111.9 86.0 197.0 106.8 108.4 93.5 133.7 146.5 157.6 135.7 171.8 105.2 113.0 131.6 127.6 124.0 100.3 73.6 71.5 96.4 167.3 124.3 68.1 149.7 95.7 114.7 99.1 70.9 136.4 92.0 167.0 199.8 101.7 145.7 102.3 59.9 47.9 49.1 44.7 61.6 55.8 55.0 54.8 57.4 54.7 42.2 50.5 53.9 28.8 60.4 75.1 48.0 66.6 41.5 39.2 42.0 43.4 52.5 42.6 44.5 42.2 40.9 41.7 39.4 41.7 42.4 107.1 73.7 83.6 26.4 137.0 212.2 169.1 116.6 99.6 75.0 101.9 118.9 95.8 57.2 104.8 115.8 60.5 131.3 116.1 131.4 256.3 112.0 153.1 110.1 125.5 106.4 101.7 98.7 38.0 104.3 167.0 107.4 67.8 127.1 112.2 220.1 62.4 137.0 124.3 57.2 39.8 136.1 87.5 107.4 104.8 307.1 78.6 113.2 64.0 33.7 142.5 82.6 126.7 19.6 32.8 111.6 106.2 87.3 128.0 179.5 164.1 330.2 68.3 130.2 32.9 156.2 127.6 215.6 174.4 116.1 209.1 177.6 117.3 319.6 151.2 163.5 ZGRF1 "C4orf21, FLJ11331" ENSG00000138658 "Zinc finger GRF-type containing 1" Q86YA3 4 112539333-112636995 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 18.0;Microglial cells: 17.8;Oligodendrocytes: 27.5;Spermatocytes: 22.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA030704, HPA030706" Uncertain Approved Cytosol NA Yes "Cluster 7: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA030704: AB_2673577, HPA030706: AB_10601784" "unprognostic (8.48e-2)" "unprognostic (6.17e-2)" "unprognostic (9.51e-2)" "unprognostic (1.53e-1)" "unprognostic (1.10e-1)" "unprognostic (1.84e-3)" "unprognostic (5.83e-3)" "unprognostic (1.45e-1)" "unprognostic (5.89e-4)" "unprognostic (4.74e-2)" "unprognostic (4.30e-2)" "unprognostic (3.72e-3)" "unprognostic (7.60e-10)" "unprognostic (3.45e-2)" "unprognostic (2.93e-1)" "unprognostic (1.15e-1)" "unprognostic (2.02e-4)" 1.0 0.7 0.9 2.0 1.4 7.8 1.3 2.2 1.5 0.9 0.1 1.1 1.2 1.2 0.3 1.0 0.8 0.5 0.7 0.8 0.7 0.5 0.6 0.9 2.5 1.3 0.9 1.1 0.7 0.3 1.3 1.7 1.3 0.9 1.4 4.3 0.9 0.4 1.2 1.4 1.5 0.9 1.0 1.8 0.9 3.6 1.0 5.2 0.8 0.6 2.9 0.7 0.8 2.1 5.0 3.6 12.1 8.6 0.9 1.6 4.7 8.8 3.7 8.7 7.8 6.9 7.3 13.2 2.5 2.7 3.6 4.0 12.7 4.7 10.0 7.3 3.1 8.3 5.8 2.1 0.4 18.5 5.3 0.8 0.6 11.0 3.0 1.2 3.5 13.6 12.0 14.3 6.0 8.2 25.0 6.7 6.3 5.2 4.2 13.8 18.1 4.5 1.5 4.4 5.6 9.5 3.9 5.3 1.7 8.8 2.5 5.4 4.2 10.9 10.6 5.9 7.1 5.5 10.1 17.0 4.9 6.3 6.3 0.0 0.1 0.3 0.2 0.7 0.1 0.3 0.1 0.0 0.0 0.5 0.4 0.4 0.2 0.2 0.1 0.7 0.2 0.1 0.9 1.4 2.2 1.5 0.8 0.7 1.3 0.9 1.3 1.0 1.0 2.1 3.3 0.0 1.3 10.4 5.4 0.0 1.3 0.0 0.6 10.4 2.1 1.7 2.4 0.0 3.7 1.8 8.4 3.5 10.4 2.1 0.0 1.0 2.9 1.8 3.5 1.9 1.2 11.1 18.0 0.5 2.7 2.3 4.6 2.8 2.5 12.2 1.1 0.6 1.8 5.0 14.5 1.8 0.0 1.6 0.0 2.8 0.6 4.1 0.0 17.8 1.3 1.6 6.2 17.6 27.5 0.6 1.4 2.2 10.5 0.8 0.7 0.3 0.7 17.6 0.0 3.1 2.7 22.1 15.6 3.6 0.0 0.8 5.0 2.2 2.5 0.9 ZNF367 FLJ33970 ENSG00000165244 "Zinc finger protein 367" Q7RTV3 9 96385941-96418370 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 22.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA015319, HPA015785" Uncertain Supported Nucleoplasm NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "HPA015319: AB_2669185, HPA015785: AB_2217750" "unprognostic (5.91e-2)" "unprognostic (2.78e-3)" "unprognostic (2.17e-2)" "unprognostic (1.11e-2)" "unprognostic (2.36e-1)" "unprognostic (4.57e-3)" "unprognostic (7.76e-3)" "unprognostic (1.60e-3)" "unprognostic (4.35e-2)" "unprognostic (3.01e-1)" "unprognostic (3.78e-3)" "unprognostic (2.71e-2)" "unprognostic (4.88e-3)" "unprognostic (3.23e-3)" "unprognostic (1.72e-1)" "prognostic favorable (2.34e-4)" "unprognostic (2.28e-1)" 1.4 0.6 0.7 3.7 1.3 26.1 1.7 1.4 1.3 1.1 0.2 3.0 2.9 1.1 0.1 2.4 0.7 1.0 2.1 0.7 1.0 3.0 10.8 1.1 4.6 1.5 1.4 1.0 1.4 1.6 0.3 1.9 1.4 1.2 3.3 1.3 0.7 0.4 1.5 3.5 3.0 2.4 0.9 1.3 2.1 6.1 1.3 8.7 1.1 2.7 4.7 1.5 1.2 2.7 25.4 10.3 9.9 8.9 3.8 5.3 13.4 34.6 20.4 16.9 20.0 6.4 17.5 19.2 14.4 16.5 12.6 30.5 11.6 12.6 19.9 21.2 10.0 14.0 19.1 5.3 0.0 19.8 16.5 0.9 0.8 13.7 6.9 3.7 6.3 13.3 13.0 45.4 21.7 16.9 30.4 16.1 6.7 27.9 16.7 15.3 49.9 11.7 4.9 16.8 17.4 12.0 15.3 18.1 10.6 8.0 9.4 17.3 5.7 27.6 15.8 25.6 26.6 17.6 32.0 7.8 16.7 17.0 23.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.7 1.3 1.4 1.3 0.7 1.0 1.5 1.4 1.4 0.9 1.3 2.7 1.1 0.0 0.0 2.9 3.8 9.9 1.3 0.4 10.8 0.7 2.2 2.3 2.6 0.0 0.9 0.0 0.0 3.2 2.5 2.4 0.0 0.5 0.7 0.6 1.1 2.0 0.0 22.3 5.1 1.2 4.2 1.7 2.6 1.8 0.0 4.7 1.1 3.8 1.9 0.0 5.3 3.6 0.0 2.1 2.6 0.8 0.6 8.3 3.6 2.8 0.1 0.6 1.0 3.0 7.9 0.7 0.5 0.7 9.6 0.6 0.9 2.5 0.0 1.5 6.6 2.0 3.6 10.3 1.7 10.9 6.5 0.8 5.0 0.3 5.6 1.1 ZNF404 ENSG00000176222 "Zinc finger protein 404" Q494X3 19 43872365-43901385 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 21.5;Oligodendrocytes: 19.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-2 OS: 43.7" "Low region specificity" "Detected in all" "HPA032014, HPA063607" Uncertain Supported "Nucleoli,Nucleoli rim,Intermediate filaments" NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 9: U-2 OS - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoli, Nucleoli rim" "Intermediate filaments" "HPA032014: AB_10602591, HPA063607: AB_2732705" "unprognostic (3.76e-3)" "unprognostic (3.41e-1)" "unprognostic (1.11e-2)" "unprognostic (4.32e-3)" "unprognostic (8.92e-2)" "unprognostic (2.82e-1)" "unprognostic (1.64e-2)" "unprognostic (2.68e-2)" "unprognostic (7.47e-2)" "unprognostic (1.26e-1)" "unprognostic (2.03e-5)" "unprognostic (1.46e-2)" "unprognostic (3.79e-3)" "unprognostic (2.89e-2)" "unprognostic (1.59e-1)" "unprognostic (2.12e-1)" "unprognostic (4.80e-3)" 2.4 3.2 9.2 1.1 10.3 0.6 2.7 9.7 11.3 3.8 8.3 5.8 0.6 2.4 9.6 2.0 6.4 2.4 9.1 8.8 9.3 3.9 2.3 2.1 3.6 9.9 9.7 6.8 2.4 2.5 14.3 2.9 9.9 6.1 1.8 18.0 2.8 2.3 2.6 3.1 2.7 2.0 9.7 5.4 3.2 4.6 10.3 2.3 4.2 1.9 1.6 4.6 2.9 12.0 3.4 0.5 3.4 0.4 8.4 11.8 2.0 4.6 2.2 2.9 4.0 0.3 1.2 0.0 4.7 2.2 0.1 0.4 0.6 2.3 3.9 0.5 3.3 1.2 0.1 1.3 3.0 0.3 0.9 7.1 5.5 2.1 2.0 9.8 2.5 0.0 0.1 0.0 2.7 0.3 0.0 0.1 2.8 0.1 0.7 0.0 1.8 0.7 2.8 2.2 1.8 1.4 1.9 0.8 2.4 6.1 0.1 1.3 1.1 4.1 43.7 3.7 2.7 5.8 8.1 0.0 5.8 0.0 2.4 0.0 0.0 0.4 0.1 0.0 0.1 0.1 0.3 0.0 0.1 0.3 0.3 0.3 0.0 0.5 0.0 0.2 0.3 0.1 9.2 10.3 9.7 11.3 8.8 9.3 9.9 9.7 9.9 9.7 10.3 12.0 1.3 0.0 3.2 21.5 1.5 0.0 0.7 1.1 0.6 3.6 1.3 1.9 7.0 0.0 0.9 0.0 0.0 1.5 0.3 0.2 0.0 0.7 1.5 1.6 3.2 1.5 2.4 0.4 6.9 0.2 1.1 1.6 0.5 1.1 7.0 2.9 1.1 0.5 0.7 5.0 6.9 0.6 4.1 0.3 0.3 0.3 0.9 0.7 0.0 1.9 0.4 3.8 2.1 3.0 19.4 0.2 0.5 3.4 0.1 0.8 0.7 0.4 1.9 3.3 0.0 0.4 1.3 1.7 3.2 0.4 0.0 1.0 1.5 0.5 0.9 0.5 ZNF672 FLJ22301 ENSG00000171161 "Zinc finger protein 672" Q499Z4 1 248838210-248849517 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 71.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055779, HPA062506" Approved Enhanced Nucleoplasm Yes Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 29: U-266 - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA055779: AB_2682917, HPA062506: AB_2684786" "unprognostic (1.64e-2)" "unprognostic (3.45e-2)" "unprognostic (8.96e-2)" "unprognostic (2.92e-2)" "unprognostic (2.50e-1)" "unprognostic (9.54e-3)" "unprognostic (7.42e-3)" "unprognostic (1.08e-2)" "unprognostic (2.50e-1)" "unprognostic (2.40e-2)" "prognostic favorable (7.51e-4)" "unprognostic (9.03e-2)" "unprognostic (1.16e-2)" "unprognostic (1.99e-2)" "unprognostic (2.69e-1)" "unprognostic (8.35e-3)" "prognostic favorable (1.79e-5)" 13.4 14.8 13.4 11.7 14.8 13.5 13.1 17.9 14.1 13.3 14.6 16.1 11.3 14.3 7.7 19.1 14.9 7.8 30.2 12.8 13.4 22.3 26.1 17.0 14.8 17.2 14.8 11.1 18.0 16.2 17.1 9.3 14.8 24.0 8.4 10.7 17.6 8.2 49.5 17.9 16.8 8.1 14.0 19.8 16.9 16.0 14.9 15.8 20.2 35.7 14.0 16.8 13.7 15.8 19.4 21.5 17.2 19.5 9.4 6.6 33.0 17.8 9.7 12.7 13.6 11.8 19.7 22.0 18.1 11.7 9.6 18.8 9.4 13.3 8.0 32.5 5.3 33.7 20.0 16.0 12.0 14.6 24.4 7.4 10.7 16.6 11.5 10.2 11.7 15.2 41.5 17.6 8.8 13.8 26.8 14.5 20.0 22.3 36.5 49.1 16.3 17.4 12.9 15.6 25.5 22.2 16.0 24.0 15.9 10.2 13.8 30.1 10.0 17.5 10.5 11.6 37.3 52.8 22.2 13.2 16.0 25.1 14.5 9.2 16.3 11.9 8.8 15.9 7.2 11.9 6.3 8.8 24.3 15.0 6.7 6.3 9.2 12.7 15.4 13.6 7.8 14.0 13.4 14.8 17.9 14.1 12.8 13.4 17.2 14.8 14.8 14.0 14.9 15.8 10.7 3.2 15.2 5.9 22.3 13.0 28.2 10.1 6.8 22.0 12.8 9.8 20.2 14.3 8.1 16.5 12.5 32.0 22.0 19.5 21.5 18.3 7.8 9.5 5.7 12.0 18.0 17.0 2.2 10.7 19.9 10.0 10.2 8.9 28.0 12.5 7.5 17.2 16.8 10.1 4.0 17.6 8.2 16.4 16.9 14.6 5.6 20.6 12.4 1.9 17.8 19.5 20.6 2.5 5.2 14.6 19.7 5.7 9.6 21.1 26.5 15.8 9.0 30.5 6.6 17.5 11.7 32.4 23.4 5.5 14.6 71.3 13.5 10.6 16.9 22.5 ZNF718 FLJ90036 ENSG00000250312 "Zinc finger protein 718" Q3SXZ3 4 124501-202303 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 37.5;Excitatory neurons: 40.1;Inhibitory neurons: 58.2;Microglial cells: 47.8;Oligodendrocyte precursor cells: 62.8;Oligodendrocytes: 85.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "REH: 19.3" NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (1.96e-1)" "unprognostic (1.38e-1)" "unprognostic (5.61e-2)" "unprognostic (1.15e-2)" "unprognostic (3.62e-2)" "unprognostic (6.59e-3)" "unprognostic (1.01e-2)" "unprognostic (2.41e-2)" "unprognostic (2.60e-1)" "unprognostic (8.97e-2)" "unprognostic (2.01e-1)" "unprognostic (1.99e-1)" "prognostic favorable (7.67e-6)" "unprognostic (1.39e-1)" "unprognostic (6.52e-2)" "unprognostic (1.52e-1)" "unprognostic (1.92e-1)" 1.9 3.0 1.8 2.2 1.8 3.0 2.6 3.4 2.5 3.3 0.5 2.5 1.7 2.2 2.1 1.8 2.9 2.0 1.9 1.3 2.3 2.5 1.4 2.0 3.8 2.0 2.5 3.5 2.5 2.7 2.0 2.8 2.4 3.0 2.2 2.7 2.2 2.2 0.9 3.0 1.9 1.9 1.5 2.9 1.9 2.0 2.4 4.6 4.7 1.8 3.4 2.0 2.3 2.7 0.0 0.9 5.4 0.0 3.3 6.2 1.3 6.9 0.9 4.3 3.3 5.9 7.7 8.5 4.0 2.5 7.6 2.0 4.4 3.2 5.8 0.0 1.6 0.0 1.5 0.0 4.1 0.1 0.1 3.2 2.8 4.3 0.6 3.9 2.9 2.4 4.1 0.1 7.6 4.4 0.8 5.3 6.6 0.0 2.4 19.3 2.1 4.7 3.5 2.1 7.3 1.7 3.5 1.2 4.2 4.3 12.5 1.6 2.1 3.2 4.0 4.1 5.1 0.0 0.0 13.3 0.0 0.0 4.0 2.6 1.3 5.7 2.2 1.8 2.1 2.0 1.9 1.4 2.4 2.2 2.2 2.1 1.6 5.4 1.1 2.4 1.6 1.2 1.8 1.8 3.4 2.5 1.3 2.3 2.0 2.5 2.4 1.5 2.4 2.7 4.0 3.2 3.6 37.5 6.5 2.0 2.2 1.4 4.6 8.4 3.5 3.0 2.4 0.0 5.1 0.0 2.1 1.9 7.6 1.2 0.0 3.1 0.3 1.0 3.7 3.4 1.2 9.7 40.1 1.4 1.4 3.6 4.1 1.6 5.7 6.6 6.1 0.9 1.4 8.4 58.2 0.7 0.0 1.6 1.9 0.7 3.7 2.9 3.6 47.8 1.7 2.6 15.5 62.8 85.0 1.6 0.1 4.5 4.6 0.9 0.5 1.4 2.6 5.1 0.0 4.4 3.8 2.4 4.1 3.0 0.9 1.4 5.5 4.0 0.8 1.4 ZRANB2 "ZIS, ZIS1, ZIS2, ZNF265" ENSG00000132485 "Zinc finger RANBP2-type containing 2" O95218 1 71063291-71081289 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053960, HPA061949, HPA063298" Supported Enhanced Nucleoplasm NA Yes 13000 "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA053960: AB_2682323, HPA061949: AB_2684645, HPA063298: AB_2684979" "unprognostic (2.10e-1)" "unprognostic (7.54e-2)" "unprognostic (4.15e-3)" "unprognostic (8.11e-2)" "unprognostic (1.04e-2)" "unprognostic (2.66e-2)" "prognostic unfavorable (7.29e-5)" "unprognostic (4.25e-3)" "unprognostic (1.24e-2)" "unprognostic (7.79e-2)" "unprognostic (4.54e-2)" "prognostic unfavorable (5.70e-4)" "prognostic unfavorable (1.57e-8)" "unprognostic (3.96e-2)" "unprognostic (8.51e-2)" "unprognostic (1.40e-1)" "unprognostic (1.84e-3)" 41.0 39.4 29.7 45.3 31.1 60.0 52.6 36.9 47.0 45.0 36.8 40.8 35.5 70.7 67.6 29.3 45.4 29.6 42.7 30.7 29.1 35.3 30.2 40.4 62.5 32.0 27.7 56.7 33.8 33.2 64.5 36.3 31.6 44.2 42.9 62.1 39.5 38.0 58.9 43.4 37.9 50.1 29.3 42.6 35.6 50.4 30.3 47.6 48.5 38.9 49.3 37.9 35.2 38.8 86.8 31.1 122.3 73.0 46.5 79.8 71.0 103.2 55.6 89.2 113.2 58.7 55.5 177.6 89.0 64.2 82.7 53.5 111.1 63.9 133.4 127.5 79.9 154.5 127.3 50.0 70.8 171.5 62.7 61.7 80.3 86.1 73.5 98.1 76.3 90.3 165.1 93.6 69.6 29.3 145.0 58.4 128.7 52.9 59.6 159.8 92.3 108.4 60.5 72.6 93.8 58.3 88.7 58.8 91.4 63.7 74.7 76.8 102.5 65.9 62.1 51.9 103.8 75.7 100.6 193.8 96.4 160.3 94.6 99.1 33.4 32.1 44.5 32.3 51.2 68.8 47.5 44.0 26.8 63.1 61.2 48.7 30.7 48.2 33.8 73.4 49.6 31.2 29.7 31.1 36.9 47.0 30.7 29.1 32.0 27.7 31.6 29.3 30.3 38.8 86.9 99.3 154.5 83.6 109.8 50.6 94.4 66.1 59.7 166.5 61.4 66.5 99.9 50.1 68.4 49.7 129.3 55.1 136.9 85.8 49.0 60.2 190.3 79.9 123.5 63.5 73.0 87.1 135.3 68.2 50.4 92.6 62.7 85.7 87.4 132.8 50.7 41.8 45.4 213.7 114.7 64.5 54.9 34.5 39.7 46.2 185.4 55.7 48.0 73.1 74.8 116.6 139.0 90.5 131.9 69.2 76.5 115.5 127.5 54.8 41.2 41.1 76.5 202.2 118.3 88.1 99.2 218.7 113.0 55.3 46.5 63.5 89.6 96.4 55.1 68.5 ZSCAN31 "ZNF310P, ZNF323" ENSG00000235109 "Zinc finger and SCAN domain containing 31" Q96LW9 6 28324693-28356271 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 138.5;Late spermatids: 65.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "basophil: 17.6" "Lineage enriched" "Detected in many" 10 "granulocytes: 17.6" "Cell line enhanced" "Detected in many" "CAPAN-2: 29.5;EFO-21: 40.1;TIME: 31.0;U-2 OS: 47.6" "Low region specificity" "Detected in all" HPA007124 Approved Approved Nucleoplasm,Cytosol NA Yes "Cluster 18: Basophils - Vesicular transport" "Cluster 21: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm Cytosol "HPA007124: AB_1080703" "unprognostic (1.11e-1)" "unprognostic (4.23e-2)" "unprognostic (3.54e-3)" "unprognostic (1.68e-1)" "unprognostic (2.45e-3)" "unprognostic (6.90e-2)" "unprognostic (2.77e-1)" "unprognostic (1.29e-2)" "unprognostic (2.41e-2)" "unprognostic (4.96e-2)" "unprognostic (6.07e-2)" "unprognostic (5.10e-2)" "prognostic favorable (2.19e-5)" "unprognostic (8.43e-3)" "unprognostic (6.22e-2)" "unprognostic (1.19e-1)" "unprognostic (5.64e-2)" 5.3 3.4 10.5 2.5 12.9 4.7 13.0 24.1 18.3 8.1 4.4 9.9 4.1 19.2 9.5 11.3 7.9 18.7 7.9 15.5 8.7 6.2 5.6 10.7 2.5 14.0 10.8 19.7 7.2 4.4 6.2 3.0 14.6 8.3 6.1 8.2 6.4 9.3 9.6 13.4 4.4 12.6 11.7 2.7 16.9 20.9 12.7 4.6 13.5 8.0 4.1 5.7 6.3 21.2 2.0 2.7 4.1 19.1 0.7 0.9 6.0 0.9 1.2 0.9 0.8 2.5 29.5 0.5 40.1 1.4 5.9 6.2 2.1 1.8 0.6 3.6 1.7 6.5 16.0 4.5 1.7 14.0 8.3 0.7 16.2 1.1 1.7 1.9 28.0 5.4 7.7 4.9 4.3 2.9 2.4 3.4 1.3 1.4 12.1 6.2 3.7 3.7 2.8 2.5 13.6 3.7 26.3 16.6 3.9 3.0 8.4 4.7 31.0 6.1 47.6 1.2 2.2 2.1 3.3 0.5 0.7 6.7 1.4 17.6 0.3 0.6 1.3 0.2 1.2 1.2 1.1 1.0 0.3 1.0 0.8 1.2 0.2 1.3 0.3 1.8 0.2 0.3 10.5 12.9 24.1 18.3 15.5 8.7 14.0 10.8 14.6 11.7 12.7 21.2 7.0 28.9 3.3 15.7 0.5 0.8 2.4 7.5 14.8 8.9 3.3 2.8 7.6 2.8 11.6 3.7 0.0 1.9 1.8 4.9 7.9 2.9 138.5 6.6 1.5 7.4 6.0 0.8 27.9 8.1 0.9 4.1 10.2 5.8 2.5 2.2 1.8 4.8 0.7 1.7 11.7 2.5 16.2 0.8 1.2 65.0 3.7 0.7 1.8 4.7 0.7 7.2 1.0 4.0 18.5 4.8 2.6 5.3 2.0 1.4 1.2 8.1 3.9 5.9 6.6 2.7 3.4 11.2 4.5 6.8 2.3 0.8 1.1 2.3 3.3 1.5 ZWINT "KNTC2AP, SIP30, Zwint1" ENSG00000122952 "ZW10 interacting kinetochore protein" O95229 10 56357227-56361273 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.6;lymphoid tissue: 43.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 133.0;Extravillous trophoblasts: 108.6;Late spermatids: 208.8;Spermatocytes: 121.0;Spermatogonia: 100.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 17.0" "Lineage enriched" "Detected in many" 5 "T-cells: 17.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA005757, HPA022264" Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nuclear bodies" Cytosol "HPA005757: AB_10600224, HPA022264: AB_10600995" "unprognostic (5.59e-2)" "unprognostic (1.71e-2)" "unprognostic (2.33e-1)" "unprognostic (1.06e-2)" "unprognostic (9.38e-2)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.77e-8)" "unprognostic (6.36e-3)" "unprognostic (5.88e-2)" "unprognostic (1.45e-2)" "unprognostic (1.58e-3)" "unprognostic (1.86e-2)" "prognostic unfavorable (3.72e-12)" "unprognostic (1.40e-2)" "unprognostic (1.48e-1)" "unprognostic (5.47e-2)" "unprognostic (3.46e-1)" 2.6 2.5 1.2 15.7 1.3 41.6 6.5 1.1 1.8 3.9 1.0 18.8 13.7 3.2 1.7 12.4 2.8 2.4 1.5 1.5 1.2 4.4 4.8 2.9 26.5 1.2 1.3 1.5 2.4 5.4 0.8 10.8 1.2 2.5 22.4 0.5 3.3 1.4 0.3 10.8 14.8 6.8 1.2 5.0 12.5 26.1 1.6 43.5 3.9 0.7 33.0 5.0 4.3 1.4 199.8 154.8 107.9 120.9 7.5 10.8 88.1 143.1 108.0 169.6 153.4 275.4 116.1 102.0 53.2 49.6 79.1 99.9 153.2 108.3 156.7 259.9 80.2 101.6 120.8 129.4 0.7 169.6 131.0 5.1 6.8 157.7 64.9 20.8 86.8 134.2 140.2 121.4 151.1 160.1 150.7 108.3 77.0 135.9 188.7 151.7 209.5 54.0 53.5 87.5 99.8 61.2 135.2 304.2 35.3 62.2 197.3 163.4 47.4 73.6 189.4 76.9 223.2 105.8 55.3 176.0 103.8 210.0 94.7 0.0 0.8 0.7 2.4 3.0 0.3 1.6 5.3 3.6 1.4 0.3 6.3 3.6 0.0 3.5 2.3 1.1 17.0 3.1 1.2 1.3 1.1 1.8 1.5 1.2 1.2 1.3 1.2 1.2 1.6 1.4 0.9 3.2 1.7 0.3 11.1 18.4 6.0 20.2 4.6 2.0 9.4 5.5 1.4 2.8 7.3 5.5 0.0 73.7 3.3 17.9 0.0 9.7 74.0 7.0 4.3 5.7 0.0 133.0 1.3 13.3 108.6 10.3 16.8 8.0 0.0 27.6 7.9 3.5 49.4 0.0 0.3 22.8 14.2 8.5 8.8 208.8 5.0 9.2 7.2 0.0 2.6 1.3 0.0 0.0 0.6 8.6 16.4 2.6 42.4 1.9 8.7 6.0 2.5 0.9 0.0 1.4 10.6 121.0 100.3 24.5 8.2 23.1 7.9 6.5 39.4 8.4