Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AL592490.1 ENSG00000197991 "Novel protein" 13 61409858-61427849 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "Alveolar cells type 1: 3.2;Alveolar cells type 2: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA062669 Approved "Vesicles,Cytokinetic bridge" Yes NA "Cluster 11: Alveolar cells - Smell perception" Vesicles "Cytokinetic bridge" "HPA062669: AB_2732687" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C12orf66 FLJ32549 ENSG00000174206 "Chromosome 12 open reading frame 66" Q96MD2 12 64186316-64222296 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046743, HPA052855" Uncertain Supported "Lysosomes,Cytokinetic bridge" Yes No "Cluster 30: Non-specific - Translation" "Cluster 35: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" Lysosomes "Cytokinetic bridge" "HPA046743: AB_2679782, HPA052855: AB_2681973" "unprognostic (7.44e-3)" "unprognostic (2.38e-1)" "unprognostic (6.20e-2)" "unprognostic (2.70e-1)" "unprognostic (2.31e-1)" "unprognostic (4.62e-2)" "unprognostic (3.45e-2)" "unprognostic (2.08e-1)" "unprognostic (1.15e-1)" "unprognostic (2.94e-1)" "unprognostic (1.93e-1)" "unprognostic (3.60e-1)" "unprognostic (1.22e-1)" "unprognostic (1.57e-1)" "unprognostic (1.10e-1)" "unprognostic (7.46e-2)" "unprognostic (4.07e-2)" 2.9 4.2 3.6 3.4 5.3 1.7 5.4 4.0 4.8 2.8 1.9 2.8 3.1 2.6 4.8 4.2 3.9 2.5 2.3 3.5 4.3 5.5 8.6 2.8 4.9 4.0 4.4 3.9 5.2 5.7 2.6 2.1 4.5 2.3 3.1 1.6 2.9 2.3 4.4 5.6 2.5 2.3 3.7 5.0 3.0 3.4 4.3 3.3 5.6 3.2 4.8 2.6 3.0 6.8 5.5 8.7 1.6 4.7 4.3 7.2 4.5 3.0 3.7 4.4 2.7 2.7 4.3 17.4 4.1 2.4 7.1 6.3 6.9 5.3 4.7 13.3 4.6 6.3 2.1 2.5 5.6 6.9 3.6 5.6 9.0 5.7 10.3 5.0 3.2 12.0 8.8 11.3 4.4 10.6 7.9 6.0 7.7 6.5 6.8 4.0 4.9 13.4 6.6 6.4 3.8 3.8 4.9 6.7 4.8 4.2 10.8 4.4 2.5 4.4 2.9 4.4 2.9 14.9 13.2 9.7 6.6 5.9 5.0 0.5 2.6 0.2 3.3 2.6 5.7 8.5 6.4 5.0 4.3 7.2 8.7 8.4 0.2 4.0 1.8 3.1 10.8 4.2 3.6 5.3 4.0 4.8 3.5 4.3 4.0 4.4 4.5 3.7 4.3 6.8 3.4 3.2 2.7 5.5 9.3 2.4 8.8 3.4 7.4 2.1 5.9 4.1 2.7 7.2 5.5 9.2 2.1 6.3 4.0 1.9 9.8 4.1 9.2 3.3 4.0 3.9 4.2 3.4 7.1 5.2 3.9 3.5 7.1 3.6 1.3 3.6 1.8 10.8 4.9 0.0 5.5 2.7 4.1 6.3 2.6 7.3 4.7 4.3 1.8 1.0 2.1 2.5 1.0 3.5 17.4 2.6 2.6 1.9 2.8 4.7 2.1 12.9 2.4 1.6 0.0 7.4 2.8 4.4 8.8 6.9 4.3 1.8 5.8 4.3 3.7 4.3 C21orf91 "C21orf14, C21orf38, CSSG1, EURL, YG81" ENSG00000154642 "Chromosome 21 open reading frame 91" Q9NYK6 21 17788974-17819386 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 59.0" "Cell type enhanced" "Detected in many" "Early spermatids: 345.8;Late spermatids: 98.6;Oligodendrocytes: 103.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 111.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 107.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018288, HPA049030" Approved Approved "Microtubules,Cytokinetic bridge" Yes NA "Cluster 2: Granulocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" Microtubules "Cytokinetic bridge" "HPA018288: AB_1845710, HPA049030: AB_2680605" "unprognostic (3.28e-1)" "unprognostic (3.41e-2)" "unprognostic (3.12e-2)" "unprognostic (4.51e-2)" "unprognostic (6.19e-2)" "unprognostic (1.11e-3)" "unprognostic (2.42e-1)" "unprognostic (8.81e-3)" "unprognostic (2.79e-1)" "unprognostic (1.97e-1)" "unprognostic (3.25e-1)" "unprognostic (5.49e-2)" "unprognostic (1.24e-2)" "unprognostic (6.80e-2)" "unprognostic (1.59e-1)" "unprognostic (6.49e-2)" "unprognostic (9.90e-3)" 6.3 4.8 11.5 9.8 26.7 8.2 8.2 22.0 16.3 6.2 4.4 4.7 5.1 9.2 4.3 8.3 6.7 6.0 5.4 13.3 15.5 5.3 8.7 7.9 15.4 26.0 21.2 8.0 2.8 4.9 2.7 13.5 26.6 5.3 5.2 5.7 5.0 3.6 2.7 18.9 5.5 7.6 20.9 9.8 6.3 24.4 20.7 19.2 5.7 5.5 13.0 8.3 4.1 59.0 7.2 1.2 15.6 0.1 3.9 7.3 6.9 10.4 18.6 10.1 8.9 6.5 3.7 25.2 5.1 4.2 14.1 5.7 17.1 13.4 8.7 27.5 9.2 16.9 13.2 4.1 8.8 20.6 9.2 5.3 14.6 13.3 21.5 7.1 2.8 10.3 12.1 107.9 7.7 4.5 28.8 6.1 16.4 1.7 5.7 21.9 29.9 10.2 6.8 12.0 6.2 14.4 13.1 10.1 47.2 7.0 6.1 11.6 4.8 44.2 13.8 0.2 6.8 28.6 37.7 21.5 3.5 18.9 17.3 111.1 11.2 56.8 20.9 11.9 29.8 14.0 19.3 22.7 13.9 11.7 14.9 19.7 24.9 20.7 12.2 3.5 36.9 12.0 11.5 26.7 22.0 16.3 13.3 15.5 26.0 21.2 26.6 20.9 20.7 59.0 20.2 19.2 11.1 1.6 26.4 27.9 10.1 57.9 63.2 12.6 14.4 10.4 7.4 4.3 27.1 5.5 16.7 17.3 18.8 4.4 1.9 4.8 345.8 14.5 13.8 21.3 10.7 5.5 0.8 6.9 12.2 12.0 9.2 14.4 39.9 11.3 7.5 6.8 5.8 15.2 0.8 5.0 18.3 7.2 14.0 98.6 23.6 9.7 21.4 3.7 30.7 3.5 48.4 7.5 103.4 4.4 5.9 17.0 27.6 11.0 3.4 6.4 19.3 13.0 6.6 20.1 12.1 38.7 24.1 21.4 27.6 80.2 38.9 22.1 3.8 7.7 CAMKV "MGC8407, VACAMKL" ENSG00000164076 "CaM kinase like vesicle associated" Q8NCB2 3 49857988-49869935 "Enzymes, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "brain: 91.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 12.2;Early spermatids: 6.3;Excitatory neurons: 32.7;Inhibitory neurons: 27.0;Late spermatids: 7.8" "Group enriched" "Detected in some" 11 "glioma: 4.0;testis cancer: 5.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.6;CACO-2: 6.1;HAP1: 10.3;NTERA-2: 34.1;RPMI-8226: 6.9;SCLC-21H: 17.7;SH-SY5Y: 8.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007656, CAB034931" Enhanced Supported Approved "Nucleoplasm,Cytokinetic bridge" Yes NA "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Cytokinetic bridge" "CAB034931: AB_2068550, HPA007656: AB_1078391" "unprognostic (9.47e-4)" "unprognostic (5.65e-3)" "unprognostic (1.42e-1)" "unprognostic (2.70e-7)" "unprognostic (2.76e-1)" "unprognostic (7.95e-4)" "unprognostic (3.09e-2)" "unprognostic (2.61e-1)" "unprognostic (1.48e-1)" "unprognostic (4.30e-3)" "unprognostic (1.72e-1)" "unprognostic (8.11e-2)" "unprognostic (1.00e-3)" "unprognostic (7.61e-2)" "unprognostic (9.51e-2)" "unprognostic (1.67e-3)" 0.0 0.8 66.5 0.0 91.8 0.0 0.0 0.0 84.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 73.3 19.0 0.1 0.0 0.0 0.0 0.2 8.7 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.1 0.1 0.0 12.9 0.0 0.1 2.0 37.2 0.0 0.0 0.0 0.0 0.0 0.0 39.2 0.0 0.2 7.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.1 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.8 0.0 0.0 0.1 0.9 0.2 34.1 0.0 0.2 1.3 0.0 6.9 0.0 0.0 17.7 8.3 0.0 0.0 0.0 1.3 0.0 2.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 66.5 91.8 0.0 84.9 73.3 19.0 0.2 8.7 0.0 12.9 37.2 39.2 0.0 0.0 0.0 3.9 0.0 0.3 0.0 0.0 0.0 12.2 0.1 0.1 0.7 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 1.2 0.0 32.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.3 27.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 4.7 0.0 0.2 0.0 2.5 3.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.0 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.3 0.0 0.0 0.1 0.0 CDC42 "CDC42Hs, G25K" ENSG00000070831 "Cell division cycle 42" P60953 1 22025511-22101360 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" Hydrolase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004360, HPA069590" Approved Supported "Microtubules,Cytokinetic bridge" Yes No 2700000 "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "Microtubules, Cytokinetic bridge" "CAB004360: AB_627233, HPA069590: AB_2732138" "unprognostic (9.40e-2)" "unprognostic (1.37e-1)" "unprognostic (9.45e-3)" "unprognostic (5.11e-2)" "unprognostic (1.73e-1)" "unprognostic (9.72e-2)" "prognostic unfavorable (5.28e-5)" "unprognostic (1.09e-1)" "unprognostic (7.92e-3)" "unprognostic (1.86e-2)" "unprognostic (3.90e-2)" "unprognostic (9.41e-2)" "unprognostic (9.72e-3)" "unprognostic (2.71e-1)" "unprognostic (3.88e-2)" "unprognostic (6.38e-2)" "unprognostic (2.09e-1)" 177.4 116.1 91.7 160.2 96.5 402.9 142.7 100.1 113.8 128.6 98.4 198.2 142.3 131.3 99.8 162.3 124.8 131.7 117.0 95.2 108.8 158.8 153.5 154.1 167.9 115.5 103.7 105.9 82.5 128.4 59.6 170.3 108.4 108.3 185.4 95.9 103.8 107.5 119.9 132.0 156.9 175.0 107.4 157.5 159.9 64.2 102.2 157.7 110.6 120.9 216.8 194.8 114.9 127.1 341.9 146.4 272.2 222.0 295.0 306.4 274.2 347.3 318.8 365.5 336.2 178.0 374.5 253.1 272.8 416.7 136.2 210.7 241.1 369.3 431.1 332.4 180.1 438.1 184.5 225.4 259.1 388.5 350.5 285.6 396.6 341.0 195.2 234.7 535.6 157.8 250.8 273.4 430.2 135.6 242.9 307.5 170.2 242.9 179.3 199.6 297.6 243.3 316.2 301.3 183.4 175.8 293.4 228.7 263.4 296.3 242.3 219.1 466.3 265.3 265.2 349.3 207.8 148.6 355.9 305.8 234.5 419.3 277.6 244.3 200.6 255.1 142.4 282.3 144.3 108.0 152.0 146.7 162.3 103.4 109.5 143.5 308.3 145.0 352.2 107.2 157.4 244.8 91.7 96.5 100.1 113.8 95.2 108.8 115.5 103.7 108.4 107.4 102.2 127.1 502.1 60.9 51.8 20.9 301.0 450.6 385.5 266.0 136.1 119.1 281.1 179.6 86.9 231.6 168.0 312.6 18.8 349.6 470.1 434.9 375.6 441.3 38.0 350.5 356.5 307.7 300.4 243.0 58.5 441.9 499.6 225.2 152.4 425.8 163.6 138.2 277.0 230.9 439.2 106.0 71.0 315.4 187.2 585.4 875.2 41.3 157.8 443.4 423.4 53.4 654.9 102.5 286.3 41.7 72.9 570.5 369.7 177.1 192.9 323.1 283.1 578.2 176.2 65.2 236.7 174.2 308.3 155.3 116.2 176.6 556.6 551.6 379.2 178.6 286.7 469.6 CHMP4C "MGC22825, Shax3, VPS32C" ENSG00000164695 "Charged multivesicular body protein 4C" Q96CF2 8 81732448-81759515 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.8" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 71.6;Pancreatic endocrine cells: 78.7;Proximal enterocytes: 80.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 37.2;CAPAN-2: 41.5;hTCEpi: 51.4;hTERT-HME1: 41.6;OE19: 73.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA023763, HPA023799" Enhanced Approved "Microtubules,Cytokinetic bridge" Yes NA "Cluster 48: NK-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "Microtubules, Cytokinetic bridge" "HPA023763: , HPA023799: AB_1846670" "unprognostic (3.98e-2)" "unprognostic (6.75e-3)" "unprognostic (1.58e-1)" "unprognostic (5.19e-2)" "unprognostic (3.12e-2)" "unprognostic (2.45e-2)" "unprognostic (5.75e-2)" "prognostic unfavorable (9.33e-5)" "unprognostic (7.54e-2)" "unprognostic (8.08e-2)" "prognostic unfavorable (6.99e-5)" "unprognostic (1.99e-2)" "prognostic favorable (1.96e-6)" "unprognostic (3.29e-3)" "unprognostic (4.95e-1)" "unprognostic (2.67e-1)" "prognostic favorable (6.45e-4)" 1.7 5.8 1.2 2.1 1.3 1.2 16.6 1.6 1.3 7.5 2.8 16.2 41.8 2.3 5.8 22.6 8.7 8.0 3.6 1.1 1.0 13.9 7.7 7.2 0.5 1.5 1.4 0.5 20.1 15.8 10.1 5.8 1.5 10.0 14.8 0.2 28.1 7.6 0.2 29.1 31.7 0.8 1.1 8.5 23.7 1.1 1.4 1.9 17.5 0.5 5.2 9.7 14.2 2.0 37.2 7.6 0.0 0.2 0.0 0.0 16.6 1.9 2.2 0.1 0.0 14.3 41.5 0.1 28.8 0.0 6.4 22.1 0.2 15.7 0.0 0.0 17.9 0.7 9.9 13.6 0.8 0.1 0.1 0.0 51.4 0.0 41.6 15.3 0.0 0.0 10.0 12.4 0.0 18.4 0.1 0.3 0.1 73.1 14.9 0.1 0.0 8.3 36.3 22.0 7.9 0.1 9.9 16.3 0.1 8.5 23.9 0.2 0.0 0.1 8.9 0.1 0.2 6.5 4.3 0.2 0.0 0.1 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.4 1.9 0.0 0.1 0.0 0.1 1.2 1.3 1.6 1.3 1.1 1.0 1.5 1.4 1.5 1.1 1.4 2.0 5.3 25.6 21.5 0.0 3.2 4.6 35.4 17.1 18.2 0.0 27.2 29.3 4.1 21.5 22.4 5.5 0.0 40.2 0.6 42.0 25.4 47.4 0.4 18.6 2.9 4.0 9.1 1.7 0.1 71.6 38.9 1.0 25.5 31.0 1.3 6.5 4.2 7.6 4.4 0.0 0.1 36.4 12.2 0.3 0.7 1.3 0.0 0.9 8.8 1.0 0.0 0.0 1.0 0.0 0.1 78.7 52.8 0.0 5.7 28.9 80.4 22.6 19.1 0.0 0.0 0.2 7.0 0.3 0.7 25.0 17.5 44.5 1.3 0.1 34.4 33.6 CISH "CIS, CIS-1, G18, SOCS" ENSG00000114737 "Cytokine inducible SH2 containing protein" Q9NSE2 3 50606489-50611774 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 60.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 38.5;Distal tubular cells: 58.7;Proximal tubular cells: 58.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 4 "HDLM-2: 316.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB034039, HPA040812" Approved Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 32: T-cells - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Microtubules "Cytokinetic bridge" "CAB034039: AB_2080282, HPA040812: AB_2677148" "unprognostic (2.36e-3)" "unprognostic (7.60e-3)" "unprognostic (2.89e-2)" "prognostic favorable (1.13e-5)" "unprognostic (8.54e-2)" "unprognostic (9.38e-2)" "prognostic favorable (6.98e-4)" "unprognostic (6.97e-3)" "unprognostic (3.84e-1)" "unprognostic (2.10e-1)" "prognostic favorable (9.65e-4)" "unprognostic (1.30e-2)" "prognostic favorable (3.53e-12)" "unprognostic (2.50e-1)" "unprognostic (1.76e-1)" "unprognostic (1.15e-1)" "unprognostic (1.78e-2)" 19.0 4.8 1.0 8.7 1.0 7.6 24.5 1.1 1.3 10.0 1.9 9.9 10.2 9.4 3.1 9.6 9.8 4.5 26.5 0.9 1.4 47.6 60.7 28.0 8.5 2.8 1.9 14.5 20.2 22.1 14.3 23.2 2.2 7.5 8.9 0.3 13.1 8.9 40.0 13.3 8.8 4.9 1.7 9.9 10.4 2.3 1.6 9.7 36.4 5.2 6.7 5.9 10.0 1.5 2.4 0.8 2.8 5.9 0.7 3.4 2.5 0.6 0.6 0.3 0.4 2.3 0.6 0.0 2.0 0.9 1.3 2.8 4.7 3.8 0.3 316.3 0.8 18.7 1.8 2.5 2.1 2.5 22.0 14.2 1.6 0.7 1.3 0.2 0.6 2.0 75.6 0.6 0.6 14.8 4.1 17.4 2.7 8.7 2.9 1.8 1.2 19.4 6.3 2.7 1.4 4.7 1.0 37.7 0.7 0.8 20.9 15.4 0.5 0.8 2.2 2.8 1.4 0.3 0.4 0.0 0.5 22.7 0.4 21.3 10.2 13.7 33.8 6.2 51.1 0.9 54.0 41.6 7.0 0.4 40.5 40.6 8.6 2.0 3.9 4.6 35.3 19.6 1.0 1.0 1.1 1.3 0.9 1.4 2.8 1.9 2.2 1.7 1.6 1.5 7.1 3.2 38.5 0.0 1.8 8.0 7.4 1.9 10.2 0.7 18.3 12.1 14.3 0.0 6.7 18.4 0.0 9.1 14.1 8.9 58.7 11.7 2.6 6.6 4.3 3.5 2.4 11.6 0.1 16.4 4.0 11.6 3.6 8.5 1.3 16.9 2.2 7.0 12.7 0.0 0.0 9.6 2.0 8.4 10.0 0.6 8.4 12.8 1.8 1.0 17.3 0.1 14.4 0.0 0.0 7.2 6.7 3.8 4.0 3.0 6.5 58.2 0.8 0.2 13.1 7.6 8.8 1.0 1.3 7.3 8.9 15.9 31.0 3.4 12.1 3.6 CLSTN2 "CDHR13, CS2, CSTN2, FLJ39113" ENSG00000158258 "Calsyntenin 2" Q9H4D0 3 139935185-140577397 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 18.2;brain: 26.7;ovary: 64.7" "Cell type enriched" "Detected in many" 4 "Excitatory neurons: 552.2" "Cancer enriched" "Detected in many" 7 "breast cancer: 15.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 32.7;SCLC-21H: 14.5;SuSa: 42.7;THP-1: 9.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031342, HPA061800" Approved Uncertain "Vesicles,Cytokinetic bridge" Yes No 130000 "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "Cytokinetic bridge" "HPA031342: AB_10602800, HPA061800: AB_2684615" "unprognostic (7.58e-2)" "unprognostic (2.64e-2)" "unprognostic (8.02e-2)" "unprognostic (1.51e-3)" "unprognostic (5.52e-3)" "unprognostic (8.35e-2)" "unprognostic (1.58e-1)" "unprognostic (1.21e-1)" "unprognostic (5.58e-1)" "unprognostic (6.25e-2)" "unprognostic (2.24e-1)" "unprognostic (1.81e-1)" "unprognostic (1.71e-1)" "unprognostic (2.52e-2)" "unprognostic (3.16e-2)" "unprognostic (7.63e-5)" "unprognostic (7.22e-5)" 18.2 4.8 17.3 0.3 15.3 0.0 8.8 0.0 26.7 4.2 0.0 1.4 0.5 5.1 0.7 1.0 4.7 2.1 6.1 23.4 0.0 4.3 0.8 1.1 2.7 13.3 3.1 64.7 1.6 0.8 0.9 0.9 9.1 5.3 0.8 2.7 1.3 1.1 1.6 2.0 1.3 6.8 0.0 0.1 1.0 0.6 0.0 0.7 2.8 2.2 0.2 1.6 3.2 15.6 0.0 0.0 5.1 0.0 2.2 0.6 0.0 0.7 0.0 0.0 0.0 2.9 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.1 2.5 0.0 0.1 0.0 32.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 2.1 0.0 0.0 0.0 42.7 2.2 9.4 0.0 1.0 0.5 1.4 0.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 15.3 0.0 26.7 23.4 0.0 13.3 3.1 9.1 0.0 0.0 15.6 2.1 0.0 0.0 18.3 0.0 0.5 0.3 0.0 8.6 1.8 10.9 2.2 8.0 0.0 0.6 3.7 0.0 0.2 0.1 0.0 1.9 0.2 39.8 0.5 8.9 0.8 0.0 0.0 552.2 0.2 0.0 9.1 0.0 0.2 0.0 25.0 2.2 0.0 0.1 0.0 111.5 0.0 0.0 0.3 1.5 31.1 28.0 0.8 0.0 5.6 0.0 0.8 0.0 108.6 29.4 0.0 0.0 0.7 0.0 5.0 0.0 32.3 3.0 3.8 0.0 28.3 13.7 0.8 0.8 0.4 0.0 0.0 0.7 0.5 0.0 0.3 CNFN PLAC8L2 ENSG00000105427 Cornifelin Q9BYD5 19 42387019-42390297 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 952.0;esophagus: 3093.3;vagina: 1442.7" "Cell type enhanced" "Detected in many" "Breast glandular cells: 57.9;Breast myoepithelial cells: 51.6;Squamous epithelial cells: 71.8" "Cancer enhanced" "Detected in all" "head and neck cancer: 367.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "memory B-cell: 61.2;naive B-cell: 70.2" "Lineage enriched" "Detected in many" 12 "B-cells: 70.2" "Cell line enhanced" "Detected in many" "A549: 18.1;HEK 293: 25.7;MCF7: 12.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA049073, HPA053997" Enhanced Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Microtubules "Cytokinetic bridge" "HPA049073: AB_2680620, HPA053997: AB_2682337" "unprognostic (5.08e-2)" "unprognostic (4.21e-3)" "unprognostic (2.52e-1)" "unprognostic (7.22e-2)" "unprognostic (3.15e-2)" "unprognostic (8.35e-3)" "unprognostic (6.04e-2)" "unprognostic (2.06e-3)" "unprognostic (3.52e-1)" "unprognostic (9.44e-2)" "unprognostic (1.39e-1)" "unprognostic (8.37e-2)" "unprognostic (8.42e-2)" "unprognostic (4.83e-2)" "unprognostic (7.77e-3)" "prognostic favorable (4.02e-5)" "unprognostic (2.45e-1)" 4.3 5.3 1.8 0.4 4.2 0.6 12.9 1.9 2.2 952.0 1.3 3.2 0.4 1.5 7.3 3093.3 1.6 0.1 1.9 1.9 2.8 2.3 1.4 0.9 0.7 2.1 1.9 1.0 3.3 1.6 2.2 0.1 1.7 8.6 1.3 0.1 661.6 1.1 1.7 555.6 3.5 0.5 1.7 3.3 3.3 2.4 2.9 2.8 1.8 0.0 276.8 2.4 1442.7 1.6 6.0 18.1 0.4 1.6 0.8 0.9 0.2 1.0 0.3 0.4 0.4 1.0 1.6 5.1 8.0 0.2 1.2 2.4 1.5 2.3 0.1 0.0 25.7 0.4 6.9 1.9 0.0 0.0 0.1 1.8 4.0 1.0 0.0 0.1 0.0 4.7 1.1 0.2 0.0 12.6 0.1 0.1 6.6 8.1 5.4 2.2 0.3 2.9 1.6 2.3 2.7 7.7 3.4 5.1 2.5 2.7 6.2 2.6 0.0 0.0 5.3 0.2 0.1 5.8 7.6 3.6 0.1 2.2 0.3 0.1 4.6 0.1 1.7 3.9 0.4 61.2 1.3 1.2 5.9 70.2 0.6 0.9 1.3 0.0 0.9 1.3 0.1 2.2 1.8 4.2 1.9 2.2 1.9 2.8 2.1 1.9 1.7 1.7 2.9 1.6 32.7 3.2 2.2 0.0 24.6 4.6 16.8 28.5 14.8 0.1 57.9 51.6 0.8 2.8 20.2 33.1 0.0 0.2 2.1 24.5 7.9 13.1 1.5 20.6 3.9 9.3 32.5 3.6 0.1 2.5 0.3 2.3 4.6 23.9 4.5 7.2 3.9 0.7 5.7 0.0 0.2 33.4 14.2 3.8 7.7 3.9 5.3 6.3 3.6 0.0 6.4 0.3 7.2 0.0 0.1 2.4 39.4 4.5 0.5 11.5 43.8 12.3 10.5 0.1 0.0 0.9 8.0 0.4 17.4 71.8 12.9 0.3 1.3 1.1 41.8 27.0 COPS2 "ALIEN, CSN2, TRIP15" ENSG00000166200 "COP9 signalosome subunit 2" P61201 15 49106068-49155661 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016867, HPA018271, HPA061071" Approved Supported "Vesicles,Cytokinetic bridge" Yes No 190000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" Vesicles "Cytokinetic bridge" "HPA016867: AB_1858336, HPA018271: AB_1858335, HPA061071: AB_2684424" "unprognostic (3.47e-1)" "unprognostic (2.28e-2)" "unprognostic (1.66e-1)" "unprognostic (7.20e-2)" "unprognostic (1.86e-1)" "unprognostic (7.84e-3)" "unprognostic (1.04e-1)" "unprognostic (6.77e-2)" "unprognostic (2.49e-2)" "unprognostic (6.09e-2)" "unprognostic (3.86e-3)" "unprognostic (1.42e-1)" "unprognostic (4.35e-3)" "unprognostic (1.02e-1)" "unprognostic (1.97e-1)" "unprognostic (5.62e-2)" "unprognostic (1.10e-3)" 61.7 43.4 24.8 34.4 28.5 124.5 67.0 35.0 36.8 61.9 25.3 43.2 43.3 58.4 44.0 63.2 43.2 53.7 61.5 26.1 30.4 60.8 57.6 35.0 45.5 30.9 27.7 76.7 54.0 65.7 26.4 45.0 32.8 45.2 41.6 32.2 40.0 47.0 92.6 35.5 37.2 56.5 35.2 32.0 36.4 51.0 27.5 49.6 61.8 112.1 48.8 59.0 35.3 41.7 92.0 53.1 111.6 94.4 134.2 189.9 76.7 157.3 149.8 135.4 123.5 113.0 49.1 151.1 105.2 152.2 108.7 131.9 160.3 130.9 148.0 103.3 64.5 141.0 105.4 91.7 102.6 134.7 70.7 161.2 104.3 110.4 193.3 149.3 144.0 82.5 184.4 78.8 149.3 49.5 72.3 67.3 72.6 128.4 68.9 78.2 105.2 227.7 143.5 136.5 108.4 78.6 90.7 96.4 127.8 129.4 95.6 133.3 93.4 132.1 71.0 249.6 167.9 71.0 196.3 191.0 123.4 215.1 109.4 11.7 17.9 12.2 13.1 23.5 24.4 14.6 19.7 19.2 21.0 13.9 24.8 16.2 7.4 16.6 22.9 13.3 28.4 16.0 24.8 28.5 35.0 36.8 26.1 30.4 30.9 27.7 32.8 35.2 27.5 41.7 72.8 76.9 56.1 14.4 50.0 87.1 57.1 90.8 80.8 23.2 47.6 59.3 104.3 27.1 69.8 23.9 10.4 56.1 48.2 18.5 54.8 40.3 28.2 56.7 91.6 53.6 20.8 50.1 35.2 29.9 71.0 79.6 36.2 94.0 52.6 39.3 46.1 32.5 43.9 33.7 36.1 25.1 32.6 47.5 44.9 21.6 55.3 46.1 35.6 19.7 49.3 24.8 27.8 21.6 48.7 35.9 21.6 53.4 63.5 53.0 41.0 84.8 47.4 19.7 19.7 74.6 109.0 93.1 43.3 63.2 98.9 131.9 54.0 58.6 34.6 64.4 DESI1 "D15Wsu75e, DESI-1, FAM152B, POST, PPPDE2" ENSG00000100418 "Desumoylating isopeptidase 1" Q6ICB0 22 41598028-41621043 "Predicted intracellular proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 761.4;Late spermatids: 415.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053415 Approved Approved "Cytokinetic bridge,Cytosol" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "Cytokinetic bridge" "HPA053415: AB_2682141" "unprognostic (1.07e-1)" "unprognostic (2.07e-1)" "unprognostic (1.83e-2)" "prognostic favorable (7.70e-4)" "unprognostic (2.31e-2)" "unprognostic (6.16e-3)" "unprognostic (8.75e-3)" "unprognostic (9.27e-2)" "unprognostic (3.97e-2)" "unprognostic (6.27e-2)" "unprognostic (1.80e-2)" "unprognostic (1.42e-1)" "unprognostic (2.31e-3)" "unprognostic (2.65e-2)" "unprognostic (1.55e-1)" "unprognostic (8.18e-2)" "unprognostic (1.10e-1)" 11.9 18.5 34.3 10.4 36.0 7.5 10.9 37.1 36.6 10.7 23.6 13.3 11.6 11.2 11.3 26.4 10.2 8.9 38.1 34.4 37.5 22.3 47.3 14.7 11.6 36.1 37.9 12.4 12.5 13.1 12.2 9.3 35.5 13.0 10.6 12.9 12.0 10.6 16.1 15.5 12.6 11.3 34.9 13.5 16.4 18.7 38.6 8.8 9.2 17.6 13.6 12.7 11.9 35.3 16.7 17.4 17.0 23.4 23.5 28.0 9.6 33.0 21.0 30.0 21.9 23.2 10.4 63.2 22.2 38.2 15.7 23.8 45.7 36.8 31.1 28.6 34.7 14.2 32.5 19.7 28.8 56.4 18.4 24.1 42.2 36.8 34.1 24.3 45.8 21.7 42.0 69.5 24.0 21.2 12.9 17.2 16.8 62.2 26.0 17.3 7.2 65.2 38.0 10.5 12.1 6.3 31.8 34.5 23.0 19.3 11.4 18.3 46.8 22.0 16.0 23.4 16.3 25.4 21.1 29.7 54.4 24.4 29.7 9.1 6.6 7.8 3.3 9.0 4.3 4.1 4.0 3.9 5.2 3.7 3.5 4.3 3.8 2.1 6.2 3.0 5.3 4.2 34.3 36.0 37.1 36.6 34.4 37.5 36.1 37.9 35.5 34.9 38.6 35.3 21.2 9.6 18.9 10.7 27.1 8.7 36.6 42.1 13.1 19.8 29.7 29.8 55.2 18.6 21.7 9.2 6.2 31.1 15.0 29.0 39.2 50.8 761.4 29.5 24.7 24.1 19.7 11.8 13.9 30.2 39.5 17.6 19.4 55.0 10.8 27.6 19.6 72.9 50.4 21.9 18.1 19.9 22.4 28.1 18.6 415.8 19.0 33.8 14.2 6.5 49.4 18.6 30.9 11.6 13.3 50.0 29.5 10.5 46.5 111.0 80.1 53.7 10.8 11.4 26.3 14.3 24.3 149.4 30.7 43.6 13.2 83.6 22.4 28.9 26.3 72.3 DNHD1 "C11orf47, CCDC35, DHCD1, DKFZp686J0796, DNHD1L, FLJ32752, FLJ35709, FLJ46184" ENSG00000179532 "Dynein heavy chain domain 1" Q96M86 11 6497260-6593758 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 69.5;Erythroid cells: 35.6;Excitatory neurons: 41.4;Inhibitory neurons: 32.8;Oligodendrocyte precursor cells: 36.2;Oligodendrocytes: 67.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039698, HPA040267, HPA057639" Uncertain Approved "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Cytokinetic bridge" "HPA039698: AB_10795111, HPA040267: AB_2676913, HPA057639: AB_2683486" "unprognostic (1.01e-2)" "unprognostic (2.31e-1)" "unprognostic (5.87e-2)" "unprognostic (2.18e-2)" "unprognostic (9.96e-2)" "unprognostic (2.00e-3)" "unprognostic (1.43e-1)" "unprognostic (3.11e-1)" "unprognostic (5.38e-2)" "unprognostic (1.38e-1)" "unprognostic (1.96e-2)" "unprognostic (9.25e-3)" "unprognostic (5.45e-9)" "unprognostic (2.33e-1)" "unprognostic (2.50e-1)" "unprognostic (4.56e-4)" "unprognostic (8.15e-2)" 2.2 1.7 2.6 1.5 3.3 4.5 2.2 2.1 4.3 2.9 2.3 3.3 1.6 2.5 2.1 1.6 2.6 1.4 2.0 2.1 3.2 2.5 2.8 3.3 2.5 4.7 2.8 3.3 1.7 0.4 2.2 0.8 5.0 2.4 1.4 4.0 1.8 1.3 2.0 2.3 3.3 1.4 2.4 2.8 2.0 10.3 3.5 2.1 2.4 0.8 2.0 2.4 2.5 6.2 2.1 2.0 2.4 1.9 2.0 2.9 2.6 1.0 1.2 0.7 0.9 1.3 2.3 2.4 0.4 1.0 1.8 3.7 1.1 1.1 0.9 1.5 2.3 1.8 3.7 1.5 1.3 2.1 0.8 2.0 1.8 2.2 3.6 1.2 0.6 3.1 2.0 2.3 1.0 0.6 0.9 3.0 2.6 0.7 2.0 1.4 0.9 1.5 1.3 1.6 1.1 2.2 0.8 2.2 1.9 1.8 1.3 2.5 1.2 1.3 1.4 1.8 1.4 6.6 5.0 3.0 1.3 2.6 1.7 0.0 0.1 0.5 0.1 0.0 0.2 0.0 0.2 0.1 0.1 0.3 0.3 0.4 0.1 0.0 0.0 0.2 0.2 0.1 2.6 3.3 2.1 4.3 2.1 3.2 4.7 2.8 5.0 2.4 3.5 6.2 2.3 0.0 3.4 69.5 3.8 0.9 1.2 1.9 0.6 9.9 2.7 3.0 3.8 0.0 4.3 0.0 4.2 0.3 4.0 2.2 0.0 0.3 12.7 4.0 1.5 2.8 0.0 35.6 41.4 0.4 0.2 2.2 2.6 3.6 1.3 4.7 3.3 4.8 0.8 10.1 32.8 1.7 0.0 2.5 1.5 13.9 0.9 4.0 0.0 19.7 2.2 3.4 3.1 36.2 67.4 0.4 1.6 1.2 1.7 1.8 2.2 0.6 7.3 9.5 0.0 2.1 1.7 19.5 2.0 1.5 3.8 0.7 2.4 1.8 2.1 1.8 GLI4 "HKR4, ZNF928" ENSG00000250571 "GLI family zinc finger 4" P10075 8 143267433-143276931 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023131 Uncertain Approved "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 40: NK-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Cytokinetic bridge" "HPA023131: AB_2671080" "unprognostic (4.98e-2)" "unprognostic (2.69e-1)" "unprognostic (5.64e-3)" "unprognostic (1.65e-1)" "unprognostic (9.07e-2)" "unprognostic (2.71e-2)" "unprognostic (1.00e-2)" "unprognostic (4.57e-2)" "unprognostic (2.22e-1)" "unprognostic (2.65e-1)" "unprognostic (7.45e-3)" "unprognostic (5.03e-1)" "unprognostic (6.88e-3)" "unprognostic (4.61e-2)" "unprognostic (1.23e-1)" "unprognostic (3.21e-2)" "unprognostic (3.71e-3)" 11.6 6.6 8.8 4.7 8.2 5.8 10.7 8.3 15.4 12.3 3.3 10.8 6.4 10.3 2.1 12.8 10.2 2.7 13.0 9.6 7.1 13.7 12.0 6.9 5.6 7.4 6.8 13.4 12.6 4.6 9.3 2.0 7.5 13.4 3.7 2.5 9.2 3.9 9.2 12.9 10.4 1.8 5.1 11.6 11.5 10.4 7.5 5.5 10.1 2.0 4.8 11.3 11.1 7.2 6.7 13.5 6.2 9.9 9.9 4.1 7.0 3.9 2.3 2.9 3.5 3.9 19.1 8.7 7.2 6.5 4.2 8.7 3.4 4.3 1.9 15.3 10.3 13.4 7.1 4.6 7.1 4.2 4.3 12.9 2.3 4.0 8.5 6.7 6.4 13.2 7.2 14.1 8.0 18.5 19.7 3.5 5.8 12.8 19.0 11.9 2.9 8.8 7.0 15.0 6.0 7.0 11.7 5.0 8.2 5.7 22.1 1.9 3.6 4.3 12.1 6.2 4.1 18.6 9.7 7.0 7.0 8.0 7.3 0.0 0.3 0.0 0.3 0.3 0.6 0.4 0.4 0.2 0.1 0.3 0.6 0.2 0.3 1.1 0.0 1.1 0.6 0.2 8.8 8.2 8.3 15.4 9.6 7.1 7.4 6.8 7.5 5.1 7.5 7.2 9.5 0.0 0.0 13.1 11.2 7.4 12.7 1.3 13.6 14.6 10.9 12.2 2.0 12.8 1.1 12.9 20.9 5.0 20.6 15.4 25.4 2.6 6.3 8.2 10.6 6.8 11.5 5.9 7.2 4.0 4.5 9.5 11.7 7.3 4.5 15.8 8.9 7.7 7.2 6.7 8.4 7.6 2.0 10.1 5.7 4.3 16.1 9.9 8.8 12.2 6.9 11.9 13.4 4.5 15.5 3.6 17.9 16.6 8.8 9.4 16.4 20.1 2.3 11.9 6.6 11.2 10.6 13.4 14.7 15.8 10.7 2.9 11.9 14.6 13.7 9.9 GSTM1 "GST1, H-B, MU" ENSG00000134184 "Glutathione S-transferase mu 1" P09488 1 109687814-109709039 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 479.1;liver: 609.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Alveolar cells type 2: 6.8;Cardiomyocytes: 6.0;Club cells: 6.7;Hepatocytes: 5.5;Kupffer cells: 7.1" "Cancer enhanced" "Detected in all" "urothelial cancer: 63.1" "Region enriched" "Detected in all" 18 "cerebral cortex: 479.1" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 87.0;HeLa: 96.1;HHSteC: 78.6;hTEC/SVTERT24-B: 73.0;HUVEC TERT2: 62.4;MOLT-4: 115.4;U-266/84: 64.4" "Low region specificity" "Detected in all" "CAB022669, CAB047357, HPA048652, HPA055972, HPA055973" Approved Approved "Cytokinetic bridge,Cytosol" Yes NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" Cytosol "Cytokinetic bridge" "CAB022669: , CAB047357: , HPA048652: AB_2680478, HPA055972: AB_2682992, HPA055973: AB_2682993" "unprognostic (2.22e-2)" "unprognostic (5.35e-2)" "unprognostic (3.87e-3)" "unprognostic (3.20e-1)" "unprognostic (4.95e-2)" "unprognostic (1.03e-1)" "unprognostic (3.56e-2)" "unprognostic (1.81e-1)" "unprognostic (2.41e-1)" "unprognostic (6.55e-2)" "unprognostic (2.34e-1)" "unprognostic (3.45e-1)" "unprognostic (3.17e-2)" "unprognostic (2.12e-1)" "unprognostic (1.36e-1)" "unprognostic (2.18e-1)" "unprognostic (4.72e-3)" 55.5 155.7 26.1 17.4 26.4 9.7 56.9 24.9 479.1 61.5 26.9 39.1 27.9 38.1 69.6 152.3 45.8 29.4 30.5 25.9 25.8 37.3 609.6 28.2 1.8 25.5 26.3 178.4 66.8 48.7 33.5 8.7 26.1 47.0 22.4 10.2 43.8 128.6 69.3 73.5 47.3 64.3 25.0 63.6 59.5 57.0 26.6 33.5 27.7 0.0 17.9 127.0 135.2 25.3 0.3 0.6 0.3 1.3 0.0 0.0 0.5 0.0 0.3 0.2 0.4 1.0 7.0 26.9 0.1 41.6 0.0 1.3 0.1 0.6 0.7 0.1 0.4 87.0 96.1 1.7 78.6 0.0 0.7 0.1 0.1 73.0 0.3 48.1 62.4 50.1 0.0 56.8 2.5 0.0 115.4 0.7 54.6 0.1 0.0 0.4 0.6 11.1 9.0 0.1 5.3 0.7 0.0 0.3 0.5 2.6 1.1 44.5 0.2 35.5 2.0 0.9 0.1 45.1 64.4 3.7 30.7 1.1 2.0 2.2 26.1 32.2 28.8 39.1 31.0 30.8 31.4 28.5 77.8 32.5 33.1 32.6 2.0 30.1 17.4 41.1 38.9 28.5 26.1 26.4 24.9 479.1 25.9 25.8 25.5 26.3 26.1 25.0 26.6 25.3 0.3 9.6 6.8 0.0 0.2 1.8 0.6 2.0 0.0 0.1 2.7 1.9 6.0 2.8 6.7 0.0 0.0 0.0 0.8 0.4 0.0 1.2 0.0 0.9 1.9 0.8 0.0 0.0 0.0 0.0 0.0 1.7 0.0 1.5 2.5 0.0 5.0 5.5 0.1 0.0 0.0 0.3 0.0 7.1 2.2 0.4 3.7 0.5 0.0 0.0 0.7 2.4 0.0 0.0 0.0 0.6 0.1 2.2 0.0 0.1 1.9 0.0 5.1 0.0 0.0 0.3 1.4 0.5 0.4 0.0 1.6 0.0 0.8 0.0 0.2 1.8 GSTM4 ENSG00000168765 "Glutathione S-transferase mu 4" Q03013 1 109656099-109674836 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 149.5" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 382.8;Proximal tubular cells: 109.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "eosinophil: 351.7" "Lineage enriched" "Detected in all" 9 "granulocytes: 351.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048652, HPA055972, HPA055973" Approved Approved "Cytokinetic bridge,Cytosol" Yes NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" Cytosol "Cytokinetic bridge" "HPA048652: AB_2680478, HPA055972: AB_2682992, HPA055973: AB_2682993" "prognostic favorable (9.96e-5)" "unprognostic (1.96e-3)" "unprognostic (7.49e-2)" "unprognostic (9.92e-3)" "unprognostic (1.48e-1)" "unprognostic (1.08e-2)" "unprognostic (8.47e-2)" "unprognostic (3.48e-2)" "unprognostic (1.20e-1)" "unprognostic (4.76e-2)" "unprognostic (3.73e-1)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" "unprognostic (1.92e-2)" "unprognostic (2.20e-1)" "unprognostic (1.41e-1)" "unprognostic (2.47e-2)" 22.3 31.1 19.7 15.3 23.7 5.9 22.5 19.1 23.8 24.5 40.0 45.4 149.5 22.6 24.3 31.3 22.2 17.8 33.5 19.2 19.9 45.9 41.2 14.6 11.8 20.7 20.9 42.9 21.2 57.8 18.6 7.6 20.2 25.8 38.5 12.5 21.2 41.0 92.4 20.6 99.4 25.7 21.1 30.2 28.8 15.1 20.1 9.9 27.7 45.5 15.6 36.8 28.8 20.2 13.5 6.0 10.5 78.9 23.0 35.1 13.4 4.3 34.1 9.8 12.8 43.3 1.5 12.5 16.1 19.1 19.3 13.6 27.1 14.4 6.2 18.9 0.0 27.4 23.5 38.8 37.1 9.5 31.8 22.3 14.0 12.6 0.0 27.5 8.1 31.7 12.8 18.4 6.9 12.7 8.1 41.9 8.2 56.3 31.9 16.9 5.8 18.5 38.8 9.6 7.4 17.6 0.2 68.2 54.9 7.8 18.6 20.1 3.6 11.4 44.0 12.5 6.3 27.0 51.4 1.1 37.1 13.9 32.5 11.9 14.5 351.7 12.2 14.5 7.4 17.0 9.3 14.1 37.8 14.9 8.9 10.7 1.8 12.8 3.6 12.6 14.1 12.6 19.7 23.7 19.1 23.8 19.2 19.9 20.7 20.9 20.2 21.1 20.1 20.2 6.9 9.6 2.7 11.4 9.9 18.1 27.3 17.9 18.8 6.2 14.7 19.0 30.2 21.5 9.5 31.3 0.0 21.0 13.9 53.0 101.8 45.9 3.0 4.5 10.8 8.6 7.2 4.2 3.3 57.7 18.6 22.9 13.3 5.4 21.0 13.3 14.3 35.7 35.6 5.0 3.3 45.9 6.1 17.2 26.0 6.4 30.1 14.9 40.9 2.8 14.8 23.9 17.5 5.0 3.4 35.4 38.6 24.8 13.3 6.7 382.8 109.8 7.5 5.4 32.9 15.3 23.2 7.0 7.3 23.0 15.3 8.8 11.2 12.6 96.7 26.9 GSTM5 ENSG00000134201 "Glutathione S-transferase mu 5" P46439 1 109711780-109775428 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "breast: 929.9" "Group enriched" "Detected in many" 4 "Fibroblasts: 59.0;Leydig cells: 143.5;Muller glia cells: 213.3;Peritubular cells: 127.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "plasmacytoid DC: 3.9" "Lineage enriched" "Detected in single" 4 "dendritic cells: 3.9" "Group enriched" "Detected in some" 5 "fHDF/TERT166: 21.6;HHSteC: 10.3;HSkMC: 10.9" "HPA055972, HPA055973" Approved Uncertain "Cytokinetic bridge,Cytosol" Yes NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 5: Breast - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Cytosol "Cytokinetic bridge" "HPA055972: AB_2682992, HPA055973: AB_2682993" "unprognostic (1.46e-2)" "unprognostic (8.64e-3)" "unprognostic (5.58e-2)" "unprognostic (1.42e-1)" "unprognostic (5.34e-3)" "unprognostic (8.09e-2)" "unprognostic (9.64e-4)" "unprognostic (1.31e-2)" "unprognostic (1.44e-1)" "unprognostic (9.16e-2)" "unprognostic (3.31e-1)" "unprognostic (1.92e-2)" "unprognostic (1.42e-2)" "unprognostic (3.74e-2)" "unprognostic (4.39e-2)" "unprognostic (3.03e-3)" "unprognostic (1.40e-1)" 21.7 6.4 60.3 4.6 65.3 0.5 929.9 60.4 71.1 72.5 62.9 13.9 2.3 35.1 32.9 11.6 62.0 25.8 17.0 61.4 54.5 5.5 3.9 18.0 5.0 57.2 55.4 213.9 4.7 0.2 9.4 0.8 56.7 27.9 7.8 12.4 7.9 32.6 3.9 12.2 10.3 26.5 60.1 7.7 13.2 11.4 53.5 6.4 9.1 14.0 6.5 27.9 47.6 58.6 0.0 0.0 0.0 0.0 1.7 1.6 0.4 1.3 0.0 0.3 0.2 0.0 0.0 0.1 0.0 21.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.8 0.0 0.0 10.3 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.7 0.1 0.0 0.1 0.0 0.6 0.0 3.9 0.9 0.7 60.3 65.3 60.4 71.1 61.4 54.5 57.2 55.4 56.7 60.1 53.5 58.6 2.5 0.0 0.5 32.3 0.0 6.6 0.9 0.2 0.0 2.0 0.5 0.8 0.9 1.5 0.0 0.0 2.1 0.0 0.3 0.0 0.0 0.0 9.0 0.3 12.3 2.2 0.0 2.1 0.1 0.0 0.1 59.0 1.1 0.3 0.0 0.6 5.7 0.0 0.3 0.0 0.5 0.1 0.0 0.6 9.3 15.1 143.5 0.6 10.6 1.9 0.0 213.3 0.0 2.0 0.3 0.0 0.0 127.2 0.1 0.1 0.1 0.0 0.0 6.8 26.3 2.3 9.4 2.0 1.8 1.0 6.5 0.0 2.8 2.4 0.1 0.6 JRKL HHMJG ENSG00000183340 "JRK like" Q9Y4A0 11 96389989-96507574 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 171.1;Late spermatids: 49.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046184, HPA060341" Uncertain Approved "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 24: NB-4 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Cytokinetic bridge" "HPA046184: AB_10963576, HPA060341: AB_2732646" "unprognostic (4.59e-3)" "unprognostic (9.21e-2)" "unprognostic (3.42e-1)" "unprognostic (1.80e-2)" "unprognostic (6.90e-2)" "unprognostic (2.44e-1)" "unprognostic (5.00e-3)" "unprognostic (4.94e-2)" "unprognostic (7.55e-3)" "unprognostic (6.12e-2)" "unprognostic (3.99e-3)" "unprognostic (1.31e-1)" "unprognostic (3.20e-3)" "unprognostic (6.21e-2)" "unprognostic (1.21e-1)" "unprognostic (2.97e-1)" "unprognostic (9.57e-3)" 7.4 6.2 4.2 7.6 4.4 1.7 8.8 4.5 4.9 9.8 4.3 7.1 7.2 8.4 7.4 5.9 10.1 6.6 6.1 4.0 5.3 6.7 4.2 6.2 9.3 4.7 4.7 13.2 5.1 6.9 4.1 8.4 4.8 8.4 9.0 11.1 8.8 6.9 4.1 7.8 8.4 6.9 4.4 7.5 8.6 11.7 4.7 9.6 9.6 4.4 9.2 6.8 6.0 5.3 9.4 5.8 11.8 8.9 23.1 25.7 8.6 15.6 10.5 10.9 14.2 9.8 22.2 12.8 22.3 14.4 13.9 14.5 5.9 10.6 12.6 13.9 5.5 11.9 17.0 7.5 18.7 6.8 7.4 12.2 16.3 15.8 19.6 20.3 10.0 14.5 6.4 5.5 17.9 1.9 8.8 19.8 1.8 16.7 7.9 8.9 11.5 10.5 13.5 9.7 4.7 8.6 9.1 6.2 7.1 11.0 7.6 9.1 12.4 21.1 9.4 18.6 6.4 4.7 10.9 7.5 9.8 10.9 9.2 3.3 2.6 2.6 1.6 2.1 2.3 2.2 2.6 2.0 2.6 1.6 3.2 2.9 0.9 1.8 2.5 4.1 1.3 1.6 4.2 4.4 4.5 4.9 4.0 5.3 4.7 4.7 4.8 4.4 4.7 5.3 6.2 9.6 5.8 4.2 5.0 4.7 10.3 6.6 2.8 7.4 7.6 8.9 6.8 15.7 12.0 0.0 4.2 6.0 11.7 9.0 1.9 11.5 171.1 9.9 13.6 5.8 6.0 4.8 3.4 5.1 5.0 9.9 7.1 6.8 3.8 5.0 6.4 2.2 5.0 8.4 3.0 10.5 4.1 7.2 5.2 49.3 8.4 6.0 1.8 1.0 6.9 5.2 6.2 3.5 8.2 8.2 4.5 9.4 2.4 8.4 7.6 6.1 25.3 12.3 0.0 6.0 9.6 9.9 4.9 5.3 6.0 4.0 4.8 7.5 9.7 8.4 KCNV1 Kv8.1 ENSG00000164794 "Potassium voltage-gated channel modifier subfamily V member 1" Q6PIU1 8 109963636-109975771 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "brain: 4.9" "Group enriched" "Detected in some" 6 "Enteroendocrine cells: 7.1;Excitatory neurons: 28.2" "Cancer enhanced" "Detected in single" "renal cancer: 0.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 36.6" HPA067233 Supported "Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytokinetic bridge" "HPA067233: " "unprognostic (1.41e-1)" "unprognostic (1.81e-2)" "unprognostic (5.01e-4)" "unprognostic (2.30e-1)" "unprognostic (3.76e-2)" "unprognostic (1.13e-2)" "unprognostic (3.89e-2)" "unprognostic (2.27e-1)" "unprognostic (4.17e-2)" 0.1 0.1 1.9 0.1 4.9 0.5 0.1 0.0 4.6 0.0 0.0 0.5 0.1 0.1 0.5 0.1 0.1 0.1 0.1 3.3 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.3 0.4 0.1 0.3 0.2 0.0 0.2 0.4 0.7 0.2 0.1 0.1 0.4 0.3 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.3 0.0 0.1 0.0 0.0 1.1 0.5 0.6 0.4 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.4 0.5 0.1 0.0 0.1 0.2 0.1 0.3 0.6 0.1 0.0 0.2 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.6 0.0 0.1 0.2 0.2 0.2 0.1 0.2 0.0 0.2 0.0 0.8 0.2 0.3 0.1 0.1 0.0 0.1 0.4 0.2 0.0 0.2 0.5 0.4 0.3 0.1 0.2 0.1 0.1 0.2 0.1 0.2 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.9 4.9 0.0 4.6 3.3 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.0 7.1 0.0 28.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.8 0.0 0.0 0.0 1.5 1.7 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.3 0.0 KIAA1143 ENSG00000163807 KIAA1143 Q96AT1 3 44737661-44761619 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 245.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045018, HPA061799" Approved Enhanced "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 49: Eosinophils - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 32: U-937 - Innate immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "Cytokinetic bridge" "HPA045018: AB_10964578, HPA061799: AB_2684614" "unprognostic (1.31e-1)" "unprognostic (2.74e-1)" "prognostic favorable (3.65e-4)" "unprognostic (2.25e-1)" "unprognostic (6.00e-2)" "unprognostic (3.01e-3)" "unprognostic (2.23e-3)" "unprognostic (6.17e-2)" "unprognostic (6.42e-2)" "unprognostic (1.57e-3)" "unprognostic (3.71e-1)" "unprognostic (4.08e-2)" "prognostic favorable (3.26e-6)" "unprognostic (1.82e-1)" "unprognostic (1.85e-1)" "unprognostic (3.19e-2)" "unprognostic (6.46e-2)" 9.2 7.4 3.6 4.9 4.5 4.4 8.2 3.9 4.7 7.7 2.1 8.9 4.5 10.4 3.5 6.5 7.8 5.4 9.8 3.4 4.0 7.0 4.9 5.7 6.4 4.4 4.3 11.0 7.5 8.1 4.7 6.4 4.4 9.0 5.1 5.8 7.0 6.2 17.4 7.0 6.5 7.4 3.7 6.4 7.0 3.1 4.1 9.2 8.4 9.0 7.2 8.1 6.5 6.0 8.3 5.3 14.7 10.2 9.8 15.1 7.3 9.3 13.1 11.7 11.9 5.3 7.2 20.2 6.9 9.8 5.6 5.6 17.5 9.9 15.4 11.2 5.9 14.7 9.6 6.5 6.7 18.6 9.9 10.9 11.7 12.0 11.3 13.0 9.9 12.3 21.2 10.8 11.6 4.7 20.9 13.1 13.9 8.7 6.8 8.5 14.0 11.5 7.5 7.0 7.3 12.5 10.9 8.3 7.5 9.8 13.9 15.8 11.5 6.5 5.8 17.2 10.7 6.9 21.1 12.1 12.0 17.8 9.7 2.6 2.3 4.0 2.8 2.5 2.4 2.5 2.4 2.2 2.2 2.3 2.5 2.4 2.3 3.1 3.8 1.5 2.1 1.9 3.6 4.5 3.9 4.7 3.4 4.0 4.4 4.3 4.4 3.7 4.1 6.0 35.8 38.5 39.4 5.9 32.9 34.5 31.6 44.1 25.0 20.0 24.5 24.0 28.4 32.9 43.6 23.9 8.4 40.6 32.5 18.8 68.4 45.5 245.7 29.0 32.4 34.6 15.6 27.3 5.4 62.6 55.8 28.9 18.3 29.3 38.6 17.6 37.1 26.4 35.0 15.2 6.0 24.6 26.4 42.9 27.3 84.4 37.6 30.3 14.2 5.6 37.7 44.8 41.2 5.5 10.1 48.9 24.0 49.2 19.1 51.0 23.5 45.2 30.5 14.0 0.0 43.3 28.3 53.8 40.5 22.3 27.8 57.2 35.3 25.7 25.7 46.7 KIF18A "DKFZP434G2226, PPP1R99" ENSG00000121621 "Kinesin family member 18A" Q8NI77 11 28020619-28108156 "Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 8.2;lymphoid tissue: 9.6;testis: 13.7" "Cell type enhanced" "Detected in many" "Early spermatids: 43.1;Spermatocytes: 78.7;Spermatogonia: 28.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 4.1;memory B-cell: 1.0;NK-cell: 1.4;T-reg: 1.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA039312, HPA039484" Approved Supported "Microtubules,Cytokinetic bridge" Yes Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Microtubules, Cytokinetic bridge" "HPA039312: AB_10794087, HPA039484: AB_10795252" "unprognostic (3.79e-1)" "unprognostic (2.63e-1)" "unprognostic (7.09e-3)" "unprognostic (3.80e-2)" "unprognostic (6.56e-2)" "unprognostic (1.39e-1)" "unprognostic (1.34e-7)" "unprognostic (2.43e-3)" "unprognostic (2.04e-3)" "unprognostic (1.23e-2)" "unprognostic (1.72e-4)" "unprognostic (4.41e-2)" "unprognostic (0.00e+0)" "unprognostic (7.88e-3)" "unprognostic (1.67e-1)" "unprognostic (1.43e-1)" "unprognostic (2.50e-1)" 0.2 0.1 0.0 1.9 0.1 8.2 0.7 0.0 0.1 0.7 0.1 1.6 1.5 0.5 0.3 1.4 0.3 0.5 0.0 0.1 0.1 0.3 0.3 1.0 4.7 0.1 0.1 0.1 0.1 0.1 0.1 1.5 0.1 0.3 2.0 0.6 0.3 0.4 0.2 1.2 1.4 0.8 0.1 0.7 0.6 13.7 0.2 9.6 1.1 0.1 4.6 0.7 0.5 0.1 27.9 27.4 27.2 19.0 0.9 3.7 9.1 28.3 13.2 44.2 46.0 9.2 11.0 23.3 10.0 14.7 24.1 27.2 23.4 11.1 61.4 23.4 14.2 15.2 17.8 11.8 2.1 22.6 13.4 6.8 1.4 15.5 18.1 7.8 17.2 19.0 24.6 20.0 25.2 14.8 23.1 16.7 13.4 18.0 11.1 17.8 65.0 11.6 12.5 8.0 16.3 12.6 23.7 11.1 7.8 16.5 23.8 6.9 10.1 35.0 27.2 33.2 37.4 7.9 19.8 23.4 21.0 16.5 25.2 4.1 0.0 0.3 0.1 0.2 0.3 1.0 0.4 0.2 0.3 0.4 0.3 0.1 0.0 1.4 0.0 0.3 1.1 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 1.2 3.2 0.0 0.0 4.7 2.3 1.3 1.4 1.2 0.3 1.3 2.9 0.5 0.0 2.2 0.0 6.2 4.6 2.8 1.9 0.0 0.6 43.1 3.4 2.5 1.1 1.8 15.4 0.2 0.9 7.1 5.4 1.5 3.4 4.5 9.7 1.4 0.0 2.2 0.0 0.1 1.9 0.0 1.6 1.4 8.7 0.6 1.4 0.0 1.0 1.1 0.7 1.0 0.5 0.9 0.5 0.1 0.4 5.1 0.2 0.2 0.6 1.7 1.9 0.0 2.5 1.9 78.7 28.3 4.3 1.0 1.6 3.9 2.7 3.6 0.5 KIF20A RAB6KIFL ENSG00000112984 "Kinesin family member 20A" O95235 5 138178719-138187723 "Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.1;lymphoid tissue: 24.6;testis: 11.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 11.0;Erythroid cells: 24.6;Extravillous trophoblasts: 13.1;Granulosa cells: 11.1;Spermatocytes: 21.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "NK-cell: 6.6;T-reg: 2.5" "Group enriched" "Detected in many" 46 "NK-cells: 6.6;T-cells: 2.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA036909, HPA036910" Approved Uncertain "Nucleoplasm,Cytokinetic bridge" Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytokinetic bridge" "HPA036909: AB_10670245, HPA036910: AB_10671716" "unprognostic (7.50e-2)" "unprognostic (2.43e-1)" "unprognostic (1.39e-3)" "unprognostic (1.21e-2)" "unprognostic (3.47e-2)" "unprognostic (2.60e-2)" "prognostic unfavorable (2.14e-12)" "prognostic unfavorable (6.79e-4)" "unprognostic (2.86e-2)" "unprognostic (3.16e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (9.73e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (9.05e-2)" "unprognostic (2.61e-1)" "unprognostic (1.09e-1)" "unprognostic (3.16e-1)" 0.7 0.8 0.0 4.5 0.1 14.1 1.3 0.1 0.1 1.0 0.1 3.3 3.5 1.4 0.0 6.6 0.4 0.8 0.5 0.0 0.1 0.4 0.9 0.9 8.6 0.1 0.2 0.2 0.2 0.1 0.0 5.4 0.1 0.2 5.1 0.0 1.0 0.1 0.1 4.4 2.8 5.8 0.0 1.9 2.1 11.7 0.5 24.6 0.5 0.1 13.1 1.6 2.0 0.1 87.8 59.5 127.8 84.4 6.7 12.3 53.9 75.0 68.9 162.3 121.4 111.9 80.5 38.8 39.2 96.5 60.6 85.9 121.7 142.5 160.9 56.4 57.4 57.2 101.1 70.7 0.3 28.2 25.1 4.8 2.3 86.2 49.5 27.1 106.7 53.9 24.4 70.4 113.9 81.5 47.6 26.7 80.6 51.8 63.7 51.2 128.5 39.5 43.9 42.3 37.8 37.5 144.1 47.9 30.9 161.6 60.8 28.5 51.1 41.6 60.5 38.0 126.4 36.0 37.5 42.0 26.7 81.1 82.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 2.5 0.3 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.5 0.1 0.3 0.0 1.7 0.0 0.8 0.4 0.4 2.9 0.0 0.0 1.1 1.3 0.3 0.0 0.7 0.0 0.0 11.0 0.1 2.8 0.0 0.1 1.0 1.0 1.9 1.7 0.0 24.6 0.0 0.0 13.1 3.1 2.6 1.3 4.5 11.1 3.3 0.4 6.1 0.0 0.0 1.6 6.1 2.2 0.4 2.0 0.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.4 3.0 0.3 1.2 0.0 0.9 0.0 0.0 0.5 4.4 21.7 7.5 5.3 0.4 1.0 0.7 0.8 3.4 0.6 LARP6 "acheron, FLJ11196" ENSG00000166173 "La ribonucleoprotein 6, translational regulator" Q9BRS8 15 70829130-70854157 "Predicted intracellular proteins" "Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 429.0;Late spermatids: 259.8;Spermatocytes: 166.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-2197: 232.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020338, HPA049029" Approved Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Microtubules "Cytokinetic bridge" "HPA020338: AB_1844500, HPA049029: AB_2680604" "unprognostic (1.35e-3)" "unprognostic (1.95e-1)" "unprognostic (7.43e-2)" "unprognostic (2.63e-3)" "unprognostic (2.96e-2)" "unprognostic (4.70e-2)" "unprognostic (2.44e-2)" "unprognostic (2.80e-3)" "unprognostic (4.27e-2)" "unprognostic (2.87e-2)" "unprognostic (1.07e-1)" "unprognostic (1.28e-2)" "prognostic unfavorable (9.90e-5)" "unprognostic (4.51e-3)" "unprognostic (8.90e-2)" "unprognostic (2.13e-1)" "unprognostic (3.43e-1)" 51.4 9.8 42.8 6.5 69.8 0.1 44.0 56.9 65.5 27.5 22.8 18.5 2.1 22.8 28.4 7.9 29.0 10.9 43.4 44.5 52.0 27.9 10.6 17.9 2.3 57.8 56.6 30.4 10.9 19.6 23.6 7.7 56.4 26.1 4.0 11.8 19.5 14.1 17.6 14.0 10.3 12.1 46.8 2.6 26.9 9.6 55.9 5.1 40.8 26.1 1.5 21.1 31.0 90.4 42.3 44.2 14.1 28.3 70.2 77.9 0.1 127.7 99.0 67.4 71.2 12.9 12.0 0.0 50.9 69.9 65.4 22.7 32.0 11.2 66.4 0.4 78.3 0.2 37.6 12.0 127.1 0.2 0.2 49.0 45.6 67.9 107.5 70.6 22.2 15.4 0.1 0.6 30.4 7.3 0.3 0.3 14.9 0.0 113.9 0.2 50.6 0.3 22.0 35.9 8.4 18.5 42.5 0.5 93.1 21.7 2.3 2.4 29.6 27.4 109.6 232.0 107.5 0.2 0.3 0.4 116.9 0.0 14.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 42.8 69.8 56.9 65.5 44.5 52.0 57.8 56.6 56.4 46.8 55.9 90.4 32.3 0.0 1.1 2.9 0.1 18.1 47.7 20.4 9.6 41.4 15.4 18.3 22.2 24.3 11.8 12.9 2.1 0.5 1.0 0.3 54.8 59.4 429.0 24.6 31.8 24.5 12.0 0.0 10.8 25.1 0.8 87.5 4.1 8.4 0.0 7.5 11.4 15.3 1.2 25.2 11.8 1.5 10.2 0.6 13.3 259.8 73.3 3.2 19.6 7.5 0.1 28.5 0.0 5.5 105.9 62.9 0.0 45.9 0.5 61.9 0.0 100.9 16.8 4.8 19.7 28.3 34.8 166.8 11.0 1.4 8.9 0.4 1.9 5.3 0.6 37.7 LRRC17 "H_RG318M05.3, P37NB" ENSG00000128606 "Leucine rich repeat containing 17" Q8N6Y2 7 102913000-102945111 "Predicted secreted proteins" Osteogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 76.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 31.3;Granulosa cells: 68.6;Leydig cells: 101.9;Peritubular cells: 31.6;Sertoli cells: 65.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 94 "eosinophil: 9.9" "Lineage enriched" "Detected in single" 94 "granulocytes: 9.9" "Cell line enriched" "Detected in many" 5 "LHCN-M2: 1237.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA073458 Approved "Vesicles,Cytokinetic bridge" "Secreted in other tissues" Yes NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Cytokinetic bridge" "HPA073458: " "unprognostic (1.77e-1)" "unprognostic (7.73e-2)" "unprognostic (4.79e-2)" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (2.48e-1)" "unprognostic (4.46e-1)" "unprognostic (1.18e-1)" "unprognostic (9.76e-4)" "unprognostic (6.09e-3)" "unprognostic (2.26e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (4.12e-6)" "unprognostic (8.57e-3)" "unprognostic (4.48e-2)" "unprognostic (6.17e-2)" "prognostic unfavorable (6.30e-4)" 8.1 2.4 1.6 1.1 1.7 0.2 12.9 1.6 2.4 22.5 1.7 2.7 1.6 15.7 12.1 6.0 17.3 27.4 13.2 1.7 1.6 2.8 3.5 3.2 2.1 1.6 1.7 76.2 2.3 2.0 2.4 0.6 1.5 5.6 3.3 1.8 2.7 3.2 2.1 3.0 2.3 6.0 1.6 3.3 6.9 5.0 2.3 6.2 3.8 2.8 1.0 4.4 5.8 1.6 0.0 0.0 58.8 0.5 6.0 29.4 0.1 1.6 18.2 0.6 2.8 0.0 0.2 0.0 3.4 1.5 7.3 0.1 0.0 0.0 4.3 0.0 1.4 0.1 0.0 0.1 8.3 0.5 0.2 28.1 0.7 21.5 0.0 141.1 140.9 0.6 0.0 0.1 1237.5 0.0 0.1 0.4 3.1 0.1 0.1 0.1 244.0 0.2 0.2 0.1 1.3 1.3 0.1 0.0 0.1 0.1 0.0 1.7 11.8 0.2 1.5 15.2 2.3 1.1 0.4 0.0 0.3 0.0 0.3 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.7 1.6 2.4 1.7 1.6 1.6 1.7 1.5 1.6 2.3 1.6 3.6 0.0 1.1 4.6 0.2 0.9 0.2 0.9 0.0 3.7 0.7 0.8 1.1 0.0 0.5 1.8 2.1 0.3 0.3 0.0 0.0 1.7 3.5 2.7 15.3 4.4 0.0 0.0 6.9 0.4 0.2 31.3 1.1 4.6 1.3 68.6 6.1 0.5 0.4 0.0 8.7 0.1 2.0 0.0 2.7 2.9 101.9 0.5 5.4 10.3 0.6 0.6 0.0 2.5 5.3 0.2 0.3 31.6 0.0 0.3 0.1 0.3 0.1 2.2 65.7 16.1 17.8 0.6 0.5 0.4 0.6 0.0 0.9 6.6 0.2 0.2 MAGEE1 "DAMAGE, KIAA1587" ENSG00000198934 "MAGE family member E1" Q9HCI5 X 76427710-76431342 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 11.2;Excitatory neurons: 12.2;Horizontal cells: 28.6;Inhibitory neurons: 12.2;Sertoli cells: 19.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 7.8" "Low region specificity" "Detected in all" HPA003047 Approved Approved "Cytokinetic bridge,Cytosol" Yes No "Cluster 39: Non-specific - mRNA processing" "Cluster 10: Brain - Neuronal signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" Cytosol "Cytokinetic bridge" "HPA003047: AB_1079298" "unprognostic (9.30e-2)" "unprognostic (2.14e-1)" "unprognostic (2.24e-1)" "unprognostic (1.65e-3)" "unprognostic (1.76e-1)" "unprognostic (3.94e-2)" "unprognostic (5.61e-3)" "unprognostic (8.72e-3)" "unprognostic (2.41e-3)" "unprognostic (1.43e-1)" "prognostic favorable (3.95e-4)" "unprognostic (7.91e-2)" "prognostic favorable (6.86e-6)" "unprognostic (4.60e-3)" "unprognostic (2.71e-1)" "unprognostic (6.03e-3)" "unprognostic (5.99e-3)" 1.6 3.2 10.0 1.6 10.2 0.3 1.6 3.0 20.6 2.8 0.0 2.2 0.5 3.3 1.7 1.0 2.5 1.1 2.2 12.1 17.0 2.1 0.3 1.3 2.5 7.7 5.1 4.7 2.6 6.1 6.0 0.0 7.9 3.2 0.9 6.4 1.7 4.0 1.1 1.8 1.8 2.6 1.0 2.7 1.6 0.4 9.8 2.9 2.1 0.9 1.9 2.1 1.7 6.7 0.2 3.8 3.9 7.5 2.7 1.5 3.4 2.9 2.9 2.4 1.3 0.8 0.6 0.8 1.4 2.5 7.8 2.9 5.8 5.4 1.9 1.9 0.1 0.0 0.0 2.5 0.5 1.5 0.5 1.1 2.4 0.6 0.6 0.1 0.9 4.2 0.3 0.0 3.6 0.5 4.3 0.2 4.7 0.0 5.8 3.4 2.9 0.0 3.1 0.0 0.0 2.0 0.0 0.4 0.6 3.9 1.7 0.1 0.5 3.6 4.5 3.8 0.0 0.0 0.0 0.6 1.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.1 0.2 0.5 0.0 0.2 0.3 0.3 0.0 0.3 0.0 0.0 0.0 0.1 10.0 10.2 3.0 20.6 12.1 17.0 7.7 5.1 7.9 1.0 9.8 6.7 0.8 3.2 2.6 3.3 1.7 0.5 0.7 1.2 1.2 11.2 0.9 1.9 1.9 1.5 1.1 1.8 4.2 0.2 1.4 0.3 1.9 1.4 0.0 0.4 1.3 2.4 0.0 0.4 12.2 1.5 0.4 1.3 1.1 0.4 1.3 1.5 1.8 0.2 0.1 28.6 12.2 0.4 0.0 0.3 0.0 0.1 1.5 0.1 0.0 3.7 0.1 5.5 2.1 5.5 5.0 0.7 0.0 4.5 0.3 0.3 0.0 1.3 0.3 5.0 19.7 2.7 3.6 0.3 0.2 0.6 0.1 0.1 2.5 0.8 0.1 0.2 MEGF6 EGFL3 ENSG00000162591 "Multiple EGF like domains 6" O75095 1 3487951-3611508 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 22.4;Alveolar cells type 2: 20.6;Basal keratinocytes: 18.4;Basal squamous epithelial cells: 23.3;Melanocytes: 19.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ: 51.1;HeLa: 56.3;hTERT-RPE1: 69.7;U-2197: 55.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052129 Uncertain Approved "Microtubules,Cytokinetic bridge" "Secreted to blood" Yes No 1700000 "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Microtubules "Cytokinetic bridge" "HPA052129: AB_2681739" "unprognostic (1.95e-1)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.16e-2)" "unprognostic (2.38e-1)" "prognostic favorable (6.57e-4)" "unprognostic (1.19e-1)" "unprognostic (4.16e-2)" "unprognostic (1.73e-1)" "unprognostic (1.47e-1)" "unprognostic (2.90e-2)" "unprognostic (2.03e-1)" "unprognostic (3.09e-3)" "unprognostic (1.60e-1)" "unprognostic (1.64e-1)" "unprognostic (9.51e-2)" "unprognostic (3.43e-2)" 25.9 4.3 2.9 3.9 2.7 10.8 20.0 2.6 2.8 14.5 1.4 14.1 2.1 9.6 1.4 13.2 28.9 11.2 14.2 1.9 3.2 5.9 5.0 22.1 5.5 3.5 5.8 18.0 6.5 0.4 4.1 2.8 3.6 26.5 1.1 1.8 19.3 4.7 4.8 44.6 10.0 1.4 2.1 10.7 10.1 3.3 3.7 3.4 11.6 1.9 3.4 11.0 22.8 1.9 11.6 14.1 4.3 6.6 0.4 0.3 1.0 51.1 14.1 5.2 1.6 3.3 10.4 0.0 13.8 24.6 4.4 6.7 0.0 0.5 1.7 0.0 0.4 0.0 56.3 3.3 0.0 0.2 0.9 0.1 0.6 0.4 0.8 69.7 5.6 0.1 0.0 0.0 0.1 6.0 0.0 10.9 2.7 3.3 0.9 2.2 3.0 6.2 1.1 3.8 3.8 3.1 18.8 1.1 6.4 11.4 4.9 1.5 2.2 19.6 1.7 55.6 3.9 0.2 0.0 0.0 0.1 0.0 0.0 1.0 0.0 1.9 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.3 0.0 0.8 0.0 0.0 0.0 0.8 0.1 2.9 2.7 2.6 2.8 1.9 3.2 3.5 5.8 3.6 2.1 3.7 1.9 5.0 22.4 20.6 8.8 2.7 18.4 7.1 3.9 23.3 0.8 3.6 3.0 3.3 5.7 4.4 1.8 0.0 0.2 0.4 0.6 0.0 3.6 0.2 1.4 0.6 7.0 0.0 4.8 6.5 1.4 1.3 9.4 6.6 5.0 1.3 9.8 16.8 0.9 1.0 0.0 7.2 1.4 0.0 0.3 7.5 0.5 11.5 2.8 19.6 5.6 0.7 14.7 1.0 4.5 5.2 4.5 0.1 3.4 0.4 4.0 0.5 1.2 0.3 1.2 0.0 0.5 2.7 0.3 1.1 7.6 11.4 0.4 3.6 0.1 1.1 2.7 MRRF RRF ENSG00000148187 "Mitochondrial ribosome recycling factor" Q96E11 9 122264603-122331337 "Predicted intracellular proteins" "Protein biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 210.0;Late spermatids: 191.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047177, HPA049987" Supported Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" "Microtubules, Cytokinetic bridge" "HPA047177: AB_2679970, HPA049987: AB_2680984" "unprognostic (8.38e-2)" "unprognostic (2.17e-1)" "unprognostic (6.40e-2)" "unprognostic (6.06e-3)" "unprognostic (3.64e-2)" "unprognostic (1.11e-1)" "unprognostic (4.48e-2)" "unprognostic (3.71e-2)" "unprognostic (1.89e-2)" "unprognostic (4.44e-2)" "unprognostic (2.98e-1)" "unprognostic (9.01e-2)" "prognostic favorable (2.14e-8)" "unprognostic (3.89e-2)" "unprognostic (4.05e-1)" "unprognostic (8.02e-2)" "unprognostic (8.88e-3)" 18.9 19.3 10.4 12.1 10.7 14.2 19.3 11.7 13.3 13.9 15.3 25.1 23.7 10.1 13.1 25.5 11.4 8.8 28.2 10.6 11.3 23.4 24.3 13.3 14.0 11.4 10.9 11.3 18.3 23.2 12.5 9.0 11.3 14.7 28.6 14.5 15.3 10.6 40.6 22.1 18.5 10.1 10.6 15.6 14.4 18.1 11.3 13.8 16.3 32.1 20.4 16.9 16.4 11.5 34.7 45.8 25.6 43.0 35.7 32.5 48.7 33.7 43.0 44.5 26.0 55.0 40.6 75.0 16.7 27.0 35.5 99.3 74.1 78.8 36.3 25.2 30.3 25.6 53.4 30.5 23.6 72.3 32.7 30.5 52.7 40.0 70.8 22.4 50.4 29.6 44.2 27.8 45.1 55.1 36.2 23.6 30.0 86.0 45.7 26.8 48.8 79.7 76.6 34.8 30.3 19.9 36.2 58.3 27.9 24.3 62.8 18.2 27.1 19.5 29.6 51.0 42.0 19.1 50.1 33.0 36.8 42.4 22.8 4.7 17.5 6.0 13.3 29.0 14.2 15.6 13.3 12.5 29.8 12.7 13.8 16.5 2.0 22.9 31.3 12.9 16.3 11.1 10.4 10.7 11.7 13.3 10.6 11.3 11.4 10.9 11.3 10.6 11.3 11.5 22.7 3.2 9.1 21.9 18.8 15.4 22.1 30.3 26.2 13.2 20.1 17.3 21.8 18.6 17.8 14.7 12.5 29.0 10.8 21.4 35.2 36.0 210.0 16.2 15.7 22.5 7.8 29.3 28.6 29.5 49.2 11.1 23.9 12.1 24.7 14.5 14.3 19.2 30.4 5.0 39.1 22.0 18.3 17.0 16.5 191.7 9.6 16.0 14.2 20.6 18.3 6.3 11.3 22.1 31.0 24.0 20.6 7.5 19.4 18.1 41.2 37.3 16.2 23.5 19.7 15.1 11.7 30.2 16.6 32.5 22.4 37.1 12.3 31.1 33.9 22.7 MTUS2 "CAZIP, ICIS, KIAA0774, TIP150" ENSG00000132938 "Microtubule associated scaffold protein 2" Q5JR59 13 28820339-29505947 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "heart muscle: 50.2" "Group enriched" "Detected in some" 4 "Excitatory neurons: 548.4;Inhibitory neurons: 671.8" "Cancer enhanced" "Detected in some" "urothelial cancer: 0.9" "Region enhanced" "Detected in many" "cerebral cortex: 9.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HaCaT: 13.2;HeLa: 5.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031473, HPA031474, HPA031475" Enhanced Supported "Microtubules,Cytokinetic bridge" Yes NA "Cluster 49: Eosinophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Microtubules, Cytokinetic bridge" "HPA031473: AB_2673901, HPA031474: AB_10600109, HPA031475: AB_10600442" "unprognostic (1.67e-1)" "unprognostic (3.07e-1)" "unprognostic (1.96e-1)" "unprognostic (3.33e-3)" "unprognostic (1.00e-1)" "unprognostic (1.22e-2)" "unprognostic (2.79e-1)" "unprognostic (1.35e-1)" "unprognostic (2.87e-1)" "unprognostic (4.97e-2)" "unprognostic (1.30e-3)" "unprognostic (3.45e-2)" "unprognostic (3.91e-5)" "unprognostic (2.51e-2)" "unprognostic (5.46e-2)" "unprognostic (5.93e-2)" "unprognostic (9.62e-2)" 0.2 0.2 0.4 0.1 1.7 0.1 0.1 1.2 9.7 0.6 1.8 0.9 0.1 1.5 0.0 0.3 0.8 0.1 50.2 1.0 0.0 0.1 0.9 0.1 0.6 0.0 0.1 7.5 4.8 0.0 6.1 0.0 0.0 0.3 0.2 4.6 1.0 0.1 0.1 0.2 0.4 1.2 2.2 0.5 1.3 1.2 1.0 0.2 0.5 0.1 0.1 1.3 0.2 2.4 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.2 13.2 0.4 0.0 0.0 0.0 0.5 0.0 5.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 1.0 0.0 2.3 1.6 0.1 0.4 0.0 0.2 0.2 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.7 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 1.7 1.2 9.7 1.0 0.0 0.0 0.1 0.0 2.2 1.0 2.4 0.1 0.0 0.5 10.4 0.1 0.5 0.7 0.1 0.0 0.0 0.3 0.4 145.8 0.0 1.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 5.4 0.3 1.0 0.7 0.0 0.8 548.4 0.6 0.0 5.9 0.0 1.1 0.0 1.2 0.4 0.5 0.1 0.0 671.8 0.7 0.0 0.0 0.8 3.3 0.9 0.2 1.8 15.0 0.1 0.0 0.0 18.1 16.2 0.4 0.0 0.0 0.1 0.2 0.0 0.0 3.6 0.0 0.0 1.6 1.0 0.1 4.1 1.8 0.1 0.3 0.3 19.6 0.0 1.1 NCAPH2 "384D8-2, CAP-H2, hCAP-H2" ENSG00000025770 "Non-SMC condensin II complex subunit H2" Q6IBW4 22 50508224-50524780 "Predicted intracellular proteins" "DNA condensation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067932, HPA069056" Enhanced Supported "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 46: Basophils - DNA binding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cytokinetic bridge" "HPA067932: AB_2685926, HPA069056: AB_2686076" "unprognostic (2.01e-1)" "prognostic favorable (2.24e-8)" "unprognostic (3.65e-2)" "unprognostic (2.81e-1)" "unprognostic (5.04e-2)" "unprognostic (1.57e-2)" "prognostic unfavorable (8.25e-4)" "unprognostic (2.92e-2)" "unprognostic (8.66e-2)" "unprognostic (1.10e-1)" "unprognostic (2.26e-2)" "unprognostic (6.31e-2)" "unprognostic (2.04e-3)" "unprognostic (2.64e-2)" "unprognostic (1.80e-1)" "unprognostic (1.41e-1)" "unprognostic (3.00e-1)" 25.7 21.9 32.9 24.5 33.6 78.8 26.9 32.7 39.2 31.8 25.4 29.3 17.7 29.8 12.4 30.3 30.0 13.0 36.7 32.0 30.9 26.6 27.6 28.2 27.6 32.6 29.0 37.6 40.7 16.7 38.6 17.1 28.7 28.4 11.7 15.5 25.7 16.6 30.7 32.6 28.4 14.7 27.5 33.2 30.2 52.3 28.5 29.6 28.9 19.3 20.2 25.9 26.9 33.5 60.7 32.1 53.8 57.1 15.8 18.4 71.6 45.8 31.6 81.8 89.5 67.2 41.4 68.8 25.5 32.9 45.5 47.1 49.0 44.2 23.5 40.3 82.8 39.8 86.7 63.6 19.1 90.3 69.5 16.1 27.6 64.4 22.2 12.2 26.2 59.4 51.5 132.5 33.4 83.9 61.7 109.9 39.3 34.9 37.9 103.3 71.0 77.2 23.8 40.6 35.6 47.5 36.7 55.4 44.3 16.5 37.5 86.7 17.6 64.2 80.5 54.4 72.3 67.7 45.8 110.1 48.8 45.7 62.3 11.9 9.8 18.2 18.7 11.6 22.9 16.0 19.4 19.1 8.0 14.2 19.9 17.3 11.4 13.9 14.4 11.8 19.3 15.5 32.9 33.6 32.7 39.2 32.0 30.9 32.6 29.0 28.7 27.5 28.5 33.5 10.1 22.4 24.5 12.1 15.9 18.9 23.8 17.5 6.2 18.3 11.5 12.6 19.6 15.7 10.4 9.2 4.2 36.3 15.5 24.6 15.6 16.6 36.8 8.5 7.5 12.9 13.1 31.5 8.6 23.5 55.1 13.8 14.8 14.5 17.1 16.3 8.9 10.6 19.3 8.4 8.8 18.8 6.1 7.9 16.3 111.5 17.4 9.2 12.4 3.7 16.2 14.7 18.6 3.0 8.2 17.3 13.5 17.3 26.6 15.2 18.4 9.5 5.9 16.1 19.7 17.8 16.9 36.2 39.7 10.9 18.5 31.5 15.9 7.6 22.6 18.2 NUPR1 "COM1, p8" ENSG00000176046 "Nuclear protein 1, transcriptional regulator" O60356 16 28532708-28539008 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 1157.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 1162.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 14.3" "Lineage enriched" "Detected in single" 16 "granulocytes: 14.3" "Cell line enhanced" "Detected in many" "HHSteC: 280.6;hTCEpi: 446.5;SK-MEL-30: 344.9;T-47d: 199.1;U-87 MG: 173.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006349 Supported "Nucleoplasm,Cytokinetic bridge" Yes NA "Cluster 41: Basophils - Cellular respiration" "Cluster 25: Pancreas - Digestion" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "Cytokinetic bridge" "HPA006349: " "unprognostic (2.64e-2)" "unprognostic (2.77e-2)" "unprognostic (3.76e-2)" "unprognostic (1.86e-1)" "unprognostic (1.01e-1)" "unprognostic (4.40e-2)" "unprognostic (7.72e-3)" "unprognostic (5.77e-3)" "unprognostic (3.61e-2)" "unprognostic (2.77e-1)" "unprognostic (1.04e-2)" "unprognostic (2.32e-2)" "unprognostic (3.27e-2)" "unprognostic (1.51e-1)" "unprognostic (6.14e-2)" "unprognostic (6.36e-3)" "unprognostic (2.80e-2)" 190.1 270.7 66.9 32.2 71.3 1.2 185.8 70.4 83.7 148.5 55.3 221.1 12.3 137.8 81.8 110.1 146.3 70.7 108.8 64.7 82.8 87.8 345.4 164.4 29.9 83.9 77.0 188.9 1157.3 26.4 39.5 54.5 81.0 204.1 59.9 9.0 255.3 124.3 87.9 205.1 71.3 63.4 76.6 35.8 130.6 67.9 72.9 23.3 354.6 17.3 13.9 178.0 152.4 75.8 1.4 10.5 0.0 73.3 108.0 94.7 58.6 66.5 57.3 2.3 54.6 0.2 0.2 0.2 37.2 101.2 8.8 1.9 0.4 2.1 2.3 0.4 3.7 0.1 6.2 52.1 280.6 0.3 0.5 90.2 446.5 31.2 148.5 76.8 0.4 0.1 0.1 3.5 34.0 13.7 0.3 1.4 0.4 0.2 38.7 0.2 0.2 3.1 0.0 6.9 0.6 0.5 19.6 78.5 344.9 1.5 199.1 12.0 0.2 21.3 51.7 55.2 10.5 0.5 0.6 0.6 173.1 0.3 2.6 14.3 0.4 3.6 0.3 0.3 0.3 0.3 0.3 0.2 0.1 0.5 0.3 0.3 2.4 0.8 0.4 0.6 0.2 0.1 66.9 71.3 70.4 83.7 64.7 82.8 83.9 77.0 81.0 76.6 72.9 75.8 179.9 288.4 336.2 11.1 9.7 316.9 318.4 1162.8 253.8 3.5 379.6 348.1 146.1 121.5 639.3 323.7 2.1 142.3 5.2 276.3 21.5 242.0 14.8 186.4 291.8 165.4 61.1 53.5 0.2 567.2 73.6 407.5 58.6 597.3 20.3 198.3 262.3 734.9 296.8 1.7 0.5 464.9 225.9 45.2 115.2 61.0 528.8 100.6 154.7 3.7 6.3 200.2 1.0 0.5 4.7 222.5 71.1 704.5 7.7 374.2 0.9 272.6 514.1 5.3 203.8 129.5 368.3 9.8 4.9 211.2 531.8 707.8 20.0 66.3 376.1 483.8 PCDH20 "FLJ22218, PCDH13" ENSG00000280165 "Protocadherin 20" Q8N6Y1 13 61409685-61415522 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.0;smooth muscle: 9.0" "Cell type enhanced" "Detected in some" "Club cells: 6.2;Excitatory neurons: 8.2;Inhibitory neurons: 7.9;Intestinal goblet cells: 5.3;Ionocytes: 6.1;Oligodendrocyte precursor cells: 32.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 14 "RPTEC TERT1: 51.3" HPA062669 Approved "Vesicles,Cytokinetic bridge" Yes NA "Cluster 10: Brain - Neuronal signaling" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 68: Oligodendrocytes - Mixed function" Vesicles "Cytokinetic bridge" "HPA062669: AB_2732687" "unprognostic (2.40e-1)" "unprognostic (1.80e-1)" "unprognostic (2.45e-1)" "unprognostic (7.83e-2)" "unprognostic (6.79e-4)" "unprognostic (2.32e-2)" "unprognostic (1.56e-1)" "unprognostic (5.34e-4)" "unprognostic (6.96e-2)" "unprognostic (1.67e-1)" "unprognostic (3.12e-1)" 0.5 1.1 3.0 0.3 4.4 0.0 0.9 1.0 11.2 2.3 0.0 3.1 0.9 3.1 2.6 0.7 0.5 0.6 3.5 18.0 3.7 0.8 1.3 3.3 0.0 1.5 4.6 0.3 0.1 0.0 0.5 0.4 1.3 1.0 1.7 0.0 0.7 1.0 0.4 1.0 1.0 9.0 2.3 1.2 1.0 0.1 2.8 0.8 0.2 0.7 0.0 0.6 0.5 2.3 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 51.3 0.0 0.7 1.9 0.0 3.6 0.5 0.1 1.0 0.1 0.0 0.0 0.0 0.0 0.4 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 4.4 1.0 11.2 18.0 3.7 1.5 4.6 1.3 2.3 2.8 2.3 0.0 3.2 0.5 2.3 0.0 0.1 0.1 3.6 0.0 0.0 0.0 0.0 0.6 0.0 6.2 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 8.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 7.9 5.3 6.1 0.0 0.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 32.6 1.0 0.1 2.3 0.0 0.0 0.1 0.0 0.0 2.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.2 PDCD2 "RP8, ZMYND7" ENSG00000071994 "Programmed cell death 2" Q16342 6 170575295-170584692 "Predicted intracellular proteins" Apoptosis DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026713, HPA075534" Approved Approved "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 32: Non-specific - Translation" Nucleoplasm "Cytokinetic bridge" "HPA026713: AB_1855103, HPA075534: AB_2686754" "unprognostic (3.80e-3)" "unprognostic (1.90e-2)" "unprognostic (1.37e-2)" "unprognostic (4.61e-2)" "unprognostic (5.83e-2)" "unprognostic (8.91e-3)" "prognostic unfavorable (1.42e-6)" "unprognostic (9.91e-2)" "unprognostic (7.75e-2)" "unprognostic (1.25e-2)" "unprognostic (3.17e-2)" "unprognostic (3.85e-2)" "unprognostic (4.45e-3)" "unprognostic (9.16e-2)" "unprognostic (1.66e-1)" "unprognostic (2.00e-1)" "unprognostic (1.09e-1)" 26.3 25.6 18.9 30.0 19.1 35.4 43.0 20.2 23.7 27.1 18.4 31.1 32.4 25.9 39.9 32.6 33.7 23.4 22.8 19.3 20.2 33.2 32.7 23.4 43.2 19.2 20.0 29.8 45.4 29.6 16.9 28.4 19.3 25.9 38.4 17.7 31.7 30.3 36.4 25.8 25.9 28.7 19.0 27.5 30.6 19.9 19.5 42.3 34.6 27.0 50.6 32.8 21.6 19.3 50.5 36.2 53.8 126.7 75.8 82.6 59.3 58.6 66.7 67.9 75.3 65.2 43.1 90.6 46.6 64.8 90.8 70.5 116.5 97.1 98.9 74.7 127.2 128.6 46.2 119.3 91.9 161.6 83.3 75.6 93.4 86.2 138.7 71.2 95.8 123.9 260.3 57.7 84.1 109.5 113.0 116.6 77.5 161.6 54.9 79.4 41.5 117.8 103.7 29.3 98.4 102.4 66.7 107.8 71.6 58.1 54.8 162.8 73.0 33.3 71.4 80.1 105.1 76.5 96.4 97.9 62.1 154.9 87.0 4.1 12.4 11.5 14.1 12.0 16.5 14.2 15.9 14.9 17.3 13.8 15.5 14.8 5.3 18.8 15.2 15.9 20.3 12.0 18.9 19.1 20.2 23.7 19.3 20.2 19.2 20.0 19.3 19.0 19.5 19.3 47.2 12.8 15.3 9.4 54.1 49.5 76.4 14.6 40.5 36.9 58.0 59.7 27.4 52.9 14.0 29.5 12.5 63.9 82.2 29.2 78.2 55.3 17.0 36.1 38.5 38.8 47.2 64.1 13.2 74.1 71.6 32.2 32.1 33.5 15.9 59.8 44.6 28.2 49.2 16.8 12.7 44.0 22.4 41.9 33.2 15.0 49.0 40.9 35.6 8.4 62.8 34.7 84.5 8.0 12.4 58.6 36.4 40.6 58.0 103.9 47.8 83.6 16.0 35.3 19.7 43.8 55.5 33.0 85.8 58.7 46.0 46.7 60.7 60.8 68.0 84.1 PGAP6 "M83, TMEM6, TMEM8, TMEM8A" ENSG00000129925 "Post-glycosylphosphatidylinositol attachment to proteins 6" Q9HCN3 16 370788-387113 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 63.7;Hofbauer cells: 29.2;Syncytiotrophoblasts: 100.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 36.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 129.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA051281, HPA064673" Approved Supported "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Cytokinetic bridge" "HPA051281: AB_2681418, HPA064673: AB_2685317" "unprognostic (5.84e-2)" "unprognostic (6.13e-2)" "unprognostic (3.85e-2)" "unprognostic (3.21e-2)" "unprognostic (5.77e-2)" "unprognostic (3.19e-2)" "unprognostic (1.13e-3)" "unprognostic (1.56e-2)" "unprognostic (8.89e-2)" "unprognostic (7.73e-2)" "unprognostic (3.43e-1)" "unprognostic (1.38e-2)" "prognostic favorable (1.29e-5)" "unprognostic (4.20e-3)" "unprognostic (3.19e-2)" "unprognostic (4.93e-2)" "unprognostic (2.48e-1)" 23.5 25.5 13.5 18.0 15.1 30.0 20.1 11.8 17.7 17.7 14.5 39.6 31.4 19.2 24.8 31.9 17.7 16.4 37.7 12.8 11.0 59.4 57.6 36.2 17.0 14.6 12.6 12.2 102.8 19.3 28.8 34.8 13.5 30.3 10.3 5.6 40.8 12.5 36.1 11.3 38.5 8.8 11.9 36.0 53.9 63.3 16.0 11.7 28.0 10.1 7.9 23.4 14.3 14.6 12.7 32.8 18.4 33.9 24.7 22.1 36.7 35.5 36.6 17.7 25.3 129.2 57.9 13.4 47.1 34.5 27.3 17.8 8.4 39.2 4.9 38.5 31.1 22.1 23.1 74.8 56.9 16.9 40.4 25.7 11.6 27.4 7.9 18.0 41.4 14.8 36.2 20.1 22.6 78.2 23.9 33.2 29.2 20.1 12.9 51.0 21.0 31.2 28.8 32.0 21.9 25.2 19.8 19.7 106.3 9.6 35.7 33.4 61.1 50.2 53.6 35.2 19.2 40.3 21.6 27.0 25.5 17.8 32.5 7.1 7.6 10.1 10.7 8.6 8.3 2.5 8.1 8.3 3.9 2.6 10.7 8.0 36.0 1.5 6.1 4.2 6.6 5.7 13.5 15.1 11.8 17.7 12.8 11.0 14.6 12.6 13.5 11.9 16.0 14.6 11.7 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 63.7 8.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 7.4 2.9 0.0 0.0 0.0 0.0 0.0 0.0 29.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 100.2 1.4 0.0 0.0 0.0 PIK3CD p110D ENSG00000171608 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta" O00329 1 9651731-9729114 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Chemotaxis, Differentiation, Immunity, Inflammatory response, Innate immunity" "Kinase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 60.9;lymphoid tissue: 50.4" "Cell type enhanced" "Detected in many" "dendritic cells: 44.0;granulocytes: 25.3;Kupffer cells: 35.2;Microglial cells: 29.0;NK-cells: 29.9;T-cells: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 153.3;NB-4: 65.9;REH: 68.9;THP-1: 65.4;U-937: 78.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015420, HPA044953" Enhanced Approved "Vesicles,Cytokinetic bridge" Yes No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Cytokinetic bridge" "CAB015420: AB_831654, HPA044953: AB_2679153" "unprognostic (5.73e-3)" "unprognostic (2.75e-3)" "unprognostic (8.93e-2)" "unprognostic (4.05e-2)" "unprognostic (4.71e-2)" "unprognostic (1.40e-2)" "unprognostic (2.13e-1)" "unprognostic (7.42e-2)" "unprognostic (2.78e-2)" "unprognostic (1.54e-2)" "unprognostic (3.46e-2)" "unprognostic (6.75e-2)" "unprognostic (8.65e-3)" "unprognostic (2.09e-1)" "unprognostic (1.34e-1)" "unprognostic (2.04e-1)" "unprognostic (6.78e-2)" 7.2 3.1 6.8 33.4 6.3 60.9 3.9 6.1 7.5 6.2 6.4 5.4 5.2 4.9 1.7 4.9 6.1 7.0 3.3 7.0 5.3 6.4 3.5 12.0 46.9 7.3 6.6 7.0 3.0 2.9 2.8 4.2 7.8 4.6 3.4 0.6 5.1 2.7 1.2 3.0 17.2 4.7 6.6 50.4 5.7 4.0 9.3 24.3 5.5 3.5 32.0 7.4 5.1 8.5 8.1 5.2 0.4 1.4 1.3 1.1 0.7 12.1 24.5 26.0 21.1 0.3 3.3 21.5 4.9 9.8 12.4 2.4 2.0 11.0 16.2 153.3 0.4 2.4 1.3 9.0 5.1 56.0 18.7 4.3 4.5 29.2 9.8 11.4 3.8 14.9 8.0 0.1 15.0 0.6 5.4 65.9 2.2 0.3 1.4 68.9 13.0 0.7 10.9 0.0 1.7 1.5 2.7 4.9 11.9 6.8 0.8 65.4 9.8 7.7 7.9 0.2 11.5 4.9 4.9 30.1 16.7 78.6 4.4 18.0 23.5 40.2 21.6 23.0 22.6 12.8 16.3 19.9 22.5 13.6 20.9 23.1 63.2 25.9 29.2 25.7 13.3 38.3 6.8 6.3 6.1 7.5 7.0 5.3 7.3 6.6 7.8 6.6 9.3 8.5 1.7 9.6 13.4 2.0 22.2 1.5 2.2 1.8 4.0 0.7 2.0 1.7 3.1 0.0 1.1 0.0 2.1 0.3 44.0 0.1 1.9 3.9 3.0 2.0 1.7 2.7 0.0 10.3 6.7 2.0 0.5 2.9 0.0 1.0 25.3 4.2 3.6 0.0 14.7 0.0 13.4 0.1 0.0 35.2 6.0 2.8 1.2 23.1 3.6 29.0 19.3 2.5 29.9 1.0 1.1 11.3 0.0 1.5 8.2 4.1 0.2 3.8 3.3 1.3 6.6 2.0 4.7 1.5 3.4 2.9 1.1 0.3 37.1 1.5 0.2 2.1 PKN1 "DBK, MGC46204, PAK1, PKN, PRK1, PRKCL1" ENSG00000123143 "Protein kinase N1" Q16512 19 14433053-14471867 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 102.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003982, CAB010278" Approved Approved "Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" "Cytokinetic bridge" "CAB010278: AB_2163965, HPA003982: AB_1855440" "unprognostic (3.83e-2)" "unprognostic (2.14e-1)" "unprognostic (4.13e-2)" "unprognostic (1.13e-2)" "unprognostic (1.94e-1)" "unprognostic (4.58e-1)" "unprognostic (1.30e-2)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" "unprognostic (8.55e-3)" "unprognostic (4.08e-3)" "unprognostic (2.11e-1)" "unprognostic (1.45e-2)" "unprognostic (1.70e-1)" "unprognostic (8.66e-2)" "unprognostic (4.08e-1)" "unprognostic (2.24e-2)" 59.2 45.1 47.1 40.4 50.3 66.8 49.0 44.6 52.4 46.6 44.2 72.4 14.5 61.0 13.6 16.2 48.7 23.9 89.0 40.9 46.3 43.1 25.0 71.1 49.4 53.6 48.4 38.7 52.5 32.8 44.9 33.3 49.8 43.8 9.3 11.5 41.3 30.6 81.7 20.1 45.2 33.0 49.8 90.4 51.4 50.2 49.2 35.6 39.6 53.8 25.8 60.3 32.8 48.5 152.8 88.9 32.3 67.8 51.3 59.8 53.0 53.5 63.5 55.2 52.5 34.9 84.2 144.4 135.0 92.2 68.9 34.4 52.1 23.8 21.2 117.6 67.7 172.8 55.4 75.2 169.1 68.2 103.9 43.3 17.0 33.5 52.2 62.5 129.8 74.9 78.0 96.7 41.4 62.5 104.1 63.2 59.2 54.7 100.0 138.5 43.9 104.7 27.3 24.2 117.3 166.0 33.2 41.7 88.9 15.5 37.8 117.7 196.6 108.8 46.1 133.2 82.8 126.5 123.6 78.9 71.5 135.7 87.4 27.6 27.9 40.6 30.4 38.5 23.3 15.9 20.5 21.1 26.8 16.9 18.6 21.0 32.6 22.1 52.3 17.0 25.7 29.0 47.1 50.3 44.6 52.4 40.9 46.3 53.6 48.4 49.8 49.8 49.2 48.5 78.1 3.2 2.2 17.3 35.3 3.7 6.4 1.9 1.8 37.2 17.6 14.7 4.0 27.1 3.1 35.0 16.7 2.8 77.9 4.9 1.9 28.2 4.9 27.0 25.4 49.4 40.2 17.7 3.6 30.1 14.5 20.8 30.1 20.7 2.5 80.9 53.2 11.3 59.8 48.8 8.6 10.9 8.2 69.0 17.0 8.4 19.9 56.2 17.8 17.8 48.2 61.2 102.0 7.5 11.9 64.2 10.6 23.0 27.1 12.7 1.1 15.2 12.4 29.2 26.3 21.7 29.2 9.3 42.2 1.3 2.7 3.7 55.5 34.3 4.8 4.9 PKNOX2 ENSG00000165495 "PBX/knotted 1 homeobox 2" Q96KN3 11 125164687-125433389 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 36.3" "Cell type enhanced" "Detected in many" "Astrocytes: 31.3;Early spermatids: 46.8;Excitatory neurons: 132.9;Inhibitory neurons: 137.4;Oligodendrocyte precursor cells: 85.5" "Cancer enhanced" "Detected in many" "melanoma: 8.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 39.1;AN3-CA: 9.6;hTEC/SVTERT24-B: 7.8;LHCN-M2: 11.6;SK-MEL-30: 7.8;WM-115: 21.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028867, CAB034342, HPA055368, HPA066962" Supported Enhanced "Nucleoplasm,Cytokinetic bridge" Yes NA "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Cytokinetic bridge" "CAB034342: AB_2164138, HPA028867: AB_2672802, HPA055368: AB_2682796, HPA066962: AB_2685757" "unprognostic (2.91e-2)" "unprognostic (1.62e-1)" "unprognostic (2.10e-2)" "unprognostic (7.26e-2)" "unprognostic (9.46e-2)" "unprognostic (3.97e-2)" "unprognostic (2.41e-1)" "unprognostic (2.12e-2)" "unprognostic (1.56e-1)" "unprognostic (2.44e-2)" "unprognostic (7.66e-2)" "unprognostic (3.70e-1)" "unprognostic (4.10e-6)" "unprognostic (1.76e-3)" "unprognostic (7.11e-2)" "unprognostic (1.71e-2)" "unprognostic (6.48e-3)" 3.6 3.3 2.6 2.0 5.8 0.0 1.2 1.4 12.7 3.2 8.1 2.8 0.9 3.3 2.7 1.4 6.1 1.8 7.3 4.8 0.6 3.0 0.5 10.0 1.4 3.0 0.3 14.9 3.9 0.9 5.6 8.4 1.3 6.3 1.4 2.8 2.5 5.1 15.0 2.4 1.7 2.6 2.6 2.3 2.3 4.8 0.8 3.1 12.1 36.3 1.1 3.1 2.7 3.1 0.0 0.0 39.1 9.6 0.7 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 4.8 0.0 0.0 0.2 0.2 0.0 0.0 0.0 1.2 0.0 0.0 2.0 0.0 7.8 0.1 0.0 0.0 0.0 0.0 0.0 11.6 0.3 0.0 0.0 3.9 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.8 6.1 0.0 0.2 0.0 2.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 21.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 5.8 1.4 12.7 4.8 0.6 3.0 0.3 1.3 2.6 0.8 3.1 0.6 0.0 0.0 31.3 0.0 0.9 0.0 0.0 0.0 0.9 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 1.4 46.8 0.0 1.1 0.5 0.0 0.0 132.9 0.2 0.0 3.1 0.0 0.0 0.0 12.2 1.8 0.0 0.3 8.4 137.4 0.0 0.0 0.0 0.3 9.6 5.0 0.0 8.8 22.5 0.0 2.9 0.0 85.5 3.8 0.1 0.0 17.7 0.0 1.9 0.0 0.1 0.0 0.3 6.6 8.8 2.9 1.2 0.4 0.0 0.4 0.1 0.0 6.9 0.0 0.0 PPEF1 "PPEF, PPP7CA" ENSG00000086717 "Protein phosphatase with EF-hand domain 1" O14829 X 18675909-18827921 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 5.8;testis: 14.6" "Group enriched" "Detected in some" 9 "Early spermatids: 64.0;Late spermatids: 139.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.1;HeLa: 1.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034577 Uncertain "Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 78: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "Cytokinetic bridge" "HPA034577: AB_10602817" "unprognostic (4.13e-2)" "unprognostic (1.30e-1)" "unprognostic (9.06e-2)" "unprognostic (9.85e-2)" "unprognostic (3.84e-2)" "unprognostic (5.00e-2)" "unprognostic (2.38e-1)" "unprognostic (3.43e-2)" "unprognostic (4.96e-3)" "unprognostic (9.29e-2)" "unprognostic (1.70e-1)" "unprognostic (2.89e-1)" "unprognostic (1.10e-11)" "unprognostic (5.41e-3)" "unprognostic (2.75e-1)" "unprognostic (2.97e-2)" "unprognostic (1.19e-2)" 0.1 0.2 1.3 0.0 2.0 1.0 2.3 1.8 2.6 0.1 0.8 0.1 0.0 0.1 0.5 0.0 0.1 0.1 0.3 1.6 1.4 0.2 0.1 0.3 0.1 3.5 2.1 0.2 0.1 0.0 0.5 0.6 2.4 0.4 0.0 1.4 0.1 0.3 0.1 0.4 0.1 0.0 1.8 0.2 0.1 14.6 1.5 0.1 0.2 0.0 0.1 0.2 0.1 5.8 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.0 1.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.0 1.8 2.6 1.6 1.4 3.5 2.1 2.4 1.8 1.5 5.8 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 64.0 0.0 0.0 0.1 0.0 0.0 11.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.7 4.7 0.0 0.0 0.0 0.3 139.0 0.6 0.0 3.6 1.0 0.1 0.6 0.0 0.5 2.2 0.0 0.0 0.7 0.0 0.1 0.0 0.2 0.0 0.6 0.0 0.0 1.2 1.2 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 PRKACA PKACa ENSG00000072062 "Protein kinase cAMP-activated catalytic subunit alpha" P17612 19 14091688-14118084 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 310.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 116.8;Theca cells: 100.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010361, HPA071185" Approved Approved "Cytokinetic bridge,Cytosol" Yes NA 170000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 52: Non-specific - Transcription" Cytosol "Cytokinetic bridge" "CAB010361: AB_2268772, HPA071185: AB_2686356" "unprognostic (1.08e-1)" "prognostic favorable (6.28e-6)" "unprognostic (2.09e-2)" "prognostic unfavorable (6.26e-5)" "unprognostic (1.38e-2)" "unprognostic (2.95e-1)" "unprognostic (1.64e-1)" "unprognostic (9.36e-3)" "unprognostic (7.01e-2)" "unprognostic (3.41e-1)" "prognostic favorable (6.47e-4)" "unprognostic (2.86e-1)" "unprognostic (1.17e-1)" "unprognostic (4.68e-2)" "unprognostic (1.87e-1)" "unprognostic (3.66e-2)" "unprognostic (6.14e-3)" 62.7 126.5 46.6 27.6 47.6 18.9 53.9 39.9 64.2 53.2 29.5 59.0 20.9 56.9 28.5 41.8 53.7 14.2 204.8 49.2 53.3 35.4 78.4 46.1 15.9 56.8 54.5 94.1 34.0 21.6 71.2 17.3 55.3 41.2 13.0 25.2 42.3 20.8 310.9 42.3 36.3 21.8 40.7 71.6 40.2 57.2 50.3 18.2 39.6 122.1 13.4 50.6 44.2 46.6 37.5 16.3 40.3 74.4 36.2 30.8 9.9 30.5 23.6 32.7 27.5 21.6 15.0 13.8 26.2 49.2 22.9 25.4 26.7 26.6 32.3 23.1 17.7 27.7 20.6 24.4 36.8 21.9 33.5 33.8 18.1 30.0 11.1 26.6 29.7 19.0 29.1 47.3 36.7 48.1 46.3 31.9 21.5 38.7 45.0 38.0 47.8 36.7 41.7 13.5 36.5 24.2 34.2 31.3 23.8 18.1 37.2 26.5 37.7 71.7 20.3 100.7 39.6 31.9 24.9 23.6 49.6 28.0 32.7 0.1 1.5 0.2 0.8 2.7 0.3 0.8 0.3 0.5 1.1 0.5 0.5 0.7 3.2 0.4 2.5 0.6 0.3 0.6 46.6 47.6 39.9 64.2 49.2 53.3 56.8 54.5 55.3 40.7 50.3 46.6 39.5 6.4 3.4 9.4 7.0 8.8 6.8 6.4 2.2 42.2 19.2 19.0 116.8 22.8 4.7 14.7 27.1 6.9 9.0 24.6 7.9 12.4 32.4 11.7 22.9 26.7 17.5 2.5 16.9 19.1 5.7 22.6 8.6 12.9 0.0 15.9 26.4 39.7 34.5 3.3 21.6 11.8 2.0 49.4 50.8 15.7 49.0 37.1 14.2 9.4 37.8 26.1 9.2 10.1 10.7 15.6 11.6 51.9 3.3 6.4 20.7 11.8 7.0 23.9 19.7 23.3 23.5 26.4 6.9 10.1 11.2 8.1 10.0 100.6 14.4 6.6 PRKACB PKACb ENSG00000142875 "Protein kinase cAMP-activated catalytic subunit beta" P22694 1 84078062-84238498 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 334.4;Inhibitory neurons: 348.8;Oligodendrocyte precursor cells: 302.6;Oligodendrocytes: 499.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010363, HPA029754, HPA071185" Approved Approved "Cytokinetic bridge,Cytosol" Yes NA 130000 "Cluster 48: NK-cells - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Cytokinetic bridge" "CAB010363: AB_2170182, HPA029754: AB_10601491, HPA071185: AB_2686356" "unprognostic (9.38e-2)" "unprognostic (1.18e-1)" "unprognostic (6.37e-2)" "unprognostic (1.39e-1)" "unprognostic (1.58e-1)" "unprognostic (1.98e-1)" "prognostic unfavorable (9.49e-4)" "unprognostic (1.28e-1)" "unprognostic (3.28e-2)" "unprognostic (1.92e-1)" "unprognostic (2.31e-1)" "unprognostic (4.62e-2)" "prognostic favorable (1.89e-6)" "unprognostic (1.22e-1)" "unprognostic (3.28e-1)" "unprognostic (1.12e-2)" "unprognostic (2.48e-1)" 16.5 47.7 79.4 26.1 101.6 16.0 17.7 70.0 113.3 19.8 0.0 55.9 10.8 19.2 38.8 17.8 10.0 26.2 23.8 100.7 107.5 23.8 20.8 15.8 41.8 53.5 44.4 17.8 27.8 23.5 24.7 11.5 65.4 30.6 51.7 71.6 83.7 27.3 4.9 4.1 12.7 28.8 59.9 36.0 34.1 8.1 91.0 63.5 25.2 13.5 36.8 27.6 7.7 110.0 8.6 16.9 26.4 31.8 29.9 26.1 12.3 41.7 31.4 20.8 19.4 0.4 7.5 45.1 28.0 32.8 38.0 5.8 12.6 13.6 22.0 44.1 6.8 99.3 21.3 3.2 29.4 39.8 2.2 15.6 6.0 20.2 11.2 30.2 97.2 16.7 3.2 25.2 34.3 1.6 51.8 21.0 26.1 0.1 11.8 39.6 41.2 27.3 50.5 30.2 8.6 33.4 23.0 8.8 25.6 19.7 8.1 8.2 86.8 28.7 22.4 29.4 31.9 18.6 24.2 45.3 13.7 41.5 36.5 56.3 7.5 16.4 59.3 10.2 47.7 35.2 43.4 52.9 19.4 28.4 65.0 69.5 3.8 73.1 16.2 11.1 44.2 66.8 79.4 101.6 70.0 113.3 100.7 107.5 53.5 44.4 65.4 59.9 91.0 110.0 9.5 0.0 1.5 118.8 56.6 5.1 7.2 3.5 11.4 44.9 11.5 9.1 44.4 21.5 5.2 14.7 35.5 1.9 103.0 115.5 33.2 6.2 2.9 11.4 27.0 13.4 21.7 52.3 334.4 11.9 1.2 17.0 16.3 14.0 58.9 15.2 28.5 17.0 27.1 47.1 348.8 58.1 4.1 62.3 24.4 3.6 14.9 51.6 16.0 95.5 14.6 35.6 96.8 302.6 499.0 20.6 42.2 21.8 53.9 10.0 4.5 25.6 6.3 34.4 13.1 14.1 20.3 13.9 8.0 8.1 2.8 0.7 87.6 11.4 51.1 9.1 PRKACG PKACg ENSG00000165059 "Protein kinase cAMP-activated catalytic subunit gamma" P22612 9 69012504-69014113 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 152 "testis: 24.6" "Group enriched" "Detected in some" 27 "Early spermatids: 71.0;Late spermatids: 88.4;Spermatocytes: 41.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004530, HPA071185" Supported Uncertain "Cytokinetic bridge,Cytosol" Yes NA "Cluster 74: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "Cytokinetic bridge" "CAB004530: AB_628137, HPA071185: AB_2686356" "unprognostic (2.74e-1)" "unprognostic (3.61e-2)" "unprognostic (7.22e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.3 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 PRR5L "FLJ14213, PROTOR-2" ENSG00000135362 "Proline rich 5 like" Q6MZQ0 11 36296288-36465204 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 46.9;intestine: 34.7;lymphoid tissue: 36.4" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 302.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HeLa: 35.5;HMC-1: 55.7;hTERT-HME1: 57.9;SiHa: 40.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070174 Approved "Cytokinetic bridge,Cytosol" Yes No "Cluster 38: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Cytokinetic bridge, Cytosol" "HPA070174: AB_2686231" "unprognostic (6.76e-2)" "unprognostic (1.61e-1)" "unprognostic (3.48e-2)" "prognostic favorable (7.30e-5)" "unprognostic (2.34e-2)" "unprognostic (1.21e-1)" "unprognostic (1.63e-1)" "unprognostic (7.45e-2)" "unprognostic (3.61e-1)" "unprognostic (1.46e-2)" "unprognostic (3.03e-3)" "unprognostic (2.12e-1)" "prognostic unfavorable (7.71e-8)" "prognostic unfavorable (4.86e-4)" "unprognostic (1.66e-1)" "unprognostic (1.44e-1)" "unprognostic (2.98e-2)" 3.6 1.5 10.1 8.9 27.8 4.7 2.7 21.7 16.7 11.4 2.2 34.7 3.3 2.8 2.0 1.4 6.3 7.1 2.0 9.6 21.1 7.7 2.9 13.6 9.3 36.6 23.8 12.8 1.2 0.9 2.7 3.6 33.9 2.4 27.8 0.7 7.8 2.0 0.9 1.7 12.2 5.9 24.1 36.4 3.4 1.5 23.9 3.4 3.2 0.7 3.3 4.3 3.8 46.9 0.0 5.5 10.3 0.2 1.4 0.0 0.1 13.2 8.9 25.7 27.2 0.0 0.2 0.1 4.4 15.7 5.9 0.5 2.1 5.9 12.9 5.0 3.7 1.5 35.5 0.0 3.5 0.0 55.7 3.8 9.0 2.3 57.9 25.2 9.4 0.0 0.0 0.1 13.6 3.3 0.7 0.1 0.8 0.1 2.3 4.1 1.1 1.1 27.0 6.9 0.0 0.4 40.1 0.0 2.2 6.5 0.0 0.6 7.8 22.3 6.8 0.0 16.4 0.2 0.0 0.0 9.7 1.5 6.7 36.1 2.0 24.9 34.6 21.4 8.2 0.0 12.2 29.7 2.5 1.6 2.6 18.0 11.8 9.6 24.6 7.7 0.0 15.4 10.1 27.8 21.7 16.7 9.6 21.1 36.6 23.8 33.9 24.1 23.9 46.9 2.1 19.2 4.2 17.6 0.7 0.4 0.2 5.0 0.0 0.1 1.9 0.9 0.9 1.5 6.8 7.3 0.0 0.2 25.9 44.3 1.9 1.3 17.6 1.5 0.8 7.7 1.8 7.0 1.8 2.2 0.1 2.1 1.1 2.5 5.1 0.5 22.5 0.4 8.8 0.0 1.1 22.7 10.2 11.7 0.7 54.9 0.6 5.4 0.0 16.9 4.7 1.2 58.7 31.7 302.0 3.9 37.0 0.4 4.2 0.7 13.2 0.5 9.0 0.2 6.6 1.8 2.6 0.3 0.6 0.4 0.6 0.3 14.5 0.9 17.5 0.5 PSMB8 "beta5i, D6S216E, LMP7, PSMB5i, RING10" ENSG00000204264 "Proteasome 20S subunit beta 8" P28062 6 32840717-32844679 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Immunity" "Hydrolase, Protease, Threonine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046995, HPA050327" Enhanced Approved "Vesicles,Cytokinetic bridge" Yes No 2700000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Cytokinetic bridge" "HPA046995: AB_2679896, HPA050327: AB_2681088" "prognostic favorable (5.08e-4)" "unprognostic (4.22e-2)" "unprognostic (2.39e-2)" "prognostic favorable (7.16e-4)" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (7.78e-2)" "unprognostic (1.09e-1)" "unprognostic (5.71e-2)" "unprognostic (1.17e-2)" "unprognostic (2.79e-2)" "unprognostic (1.47e-1)" "unprognostic (4.14e-2)" "unprognostic (1.24e-1)" "unprognostic (4.35e-2)" "unprognostic (1.97e-3)" "unprognostic (7.11e-3)" 62.7 76.9 3.3 11.2 3.4 9.8 56.5 3.3 7.3 42.7 3.4 79.9 12.9 41.3 3.2 59.5 41.6 5.8 34.2 3.4 3.5 63.7 99.2 78.2 18.2 4.3 3.4 32.1 29.5 8.2 26.6 4.4 3.7 45.2 20.4 0.7 44.2 6.4 14.4 58.0 93.9 8.9 4.0 150.4 57.0 5.9 3.6 13.5 40.8 0.1 17.2 41.3 48.1 4.1 15.1 3.9 0.3 0.0 5.1 13.1 11.2 4.9 22.9 29.1 39.3 0.0 20.9 45.7 9.4 10.5 25.5 8.1 6.8 16.6 8.0 19.2 0.0 27.6 5.9 0.3 30.3 5.2 7.5 14.9 10.3 12.9 6.8 1.9 18.1 11.8 1.1 8.1 6.1 0.1 12.9 11.7 0.1 0.0 7.3 29.3 1.3 24.1 21.3 4.9 0.8 0.2 8.6 10.4 8.5 0.1 7.0 41.0 4.3 8.8 7.6 7.8 0.6 21.0 15.9 11.2 2.2 27.7 9.0 56.8 70.3 94.6 58.1 88.0 51.2 73.4 49.1 61.1 67.5 71.1 34.8 49.6 90.2 63.0 78.2 58.5 81.2 156.0 3.3 3.4 3.3 7.3 3.4 3.5 4.3 3.4 3.7 4.0 3.6 4.1 237.0 38.5 55.8 2.9 162.0 84.4 64.1 183.7 54.7 1.8 85.3 92.5 8.7 71.4 103.2 62.5 0.0 2.7 211.2 219.9 86.1 219.4 0.6 63.2 74.9 158.5 65.7 45.0 0.1 247.6 18.3 60.7 93.8 81.5 50.7 51.4 114.5 75.0 165.9 6.7 0.5 243.8 120.1 143.5 94.9 1.9 39.1 128.2 56.9 10.3 214.3 39.9 279.1 3.0 0.7 179.6 287.9 30.5 153.2 100.1 319.8 78.9 103.2 3.0 39.5 33.2 56.8 0.4 1.2 60.5 79.6 2.7 181.6 110.9 222.6 121.6 RMDN3 "FAM82A2, FAM82C, FLJ10579, PTPIP51, RMD3" ENSG00000137824 "Regulator of microtubule dynamics 3" Q96TC7 15 40735884-40755851 "Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 110.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009975, HPA074840" Supported Enhanced "Cytokinetic bridge,Mitochondria" Yes No 42000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 45: Intestine - Brush border" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" Mitochondria "Cytokinetic bridge" "HPA009975: AB_1078811, HPA074840: " "unprognostic (2.54e-2)" "unprognostic (3.53e-1)" "unprognostic (2.35e-2)" "unprognostic (3.97e-3)" "unprognostic (1.50e-1)" "unprognostic (2.50e-3)" "unprognostic (2.78e-2)" "unprognostic (2.54e-2)" "unprognostic (1.73e-1)" "unprognostic (1.68e-1)" "unprognostic (2.78e-2)" "unprognostic (5.94e-3)" "prognostic favorable (6.70e-8)" "unprognostic (1.71e-2)" "unprognostic (1.32e-1)" "unprognostic (5.79e-3)" "unprognostic (2.04e-3)" 30.1 22.7 37.2 16.2 40.2 24.1 26.7 38.4 48.6 18.0 31.2 18.1 43.8 15.9 5.4 22.6 18.8 16.7 16.4 36.3 36.1 18.4 37.0 36.5 15.6 40.2 38.6 17.2 27.2 36.3 10.9 19.4 36.0 17.2 9.0 6.7 33.3 15.4 20.7 21.1 51.7 11.2 37.7 13.0 21.5 13.8 42.9 15.0 19.9 14.1 8.4 20.3 17.6 41.2 19.7 17.7 21.0 35.9 19.2 17.2 36.3 50.2 19.8 34.9 25.6 63.7 21.7 16.7 65.0 27.0 26.0 66.3 26.9 37.3 3.7 44.2 33.1 53.6 51.4 31.6 62.9 36.4 41.1 30.9 34.0 25.2 23.9 16.3 24.8 32.6 57.4 44.9 15.1 40.0 27.7 23.6 16.7 52.7 34.6 42.6 25.1 38.9 28.8 32.7 49.8 18.1 39.9 53.4 19.5 8.2 41.6 39.1 37.3 37.8 27.0 51.1 42.5 34.0 42.7 26.7 26.8 38.2 42.2 4.0 13.2 5.5 28.2 17.8 25.0 16.0 20.6 26.0 14.4 13.7 15.9 17.3 2.1 65.1 22.3 54.2 20.3 26.6 37.2 40.2 38.4 48.6 36.3 36.1 40.2 38.6 36.0 37.7 42.9 41.2 20.1 32.1 28.1 18.6 11.0 15.7 16.4 26.9 15.9 20.0 21.0 13.6 8.1 15.7 27.8 18.4 4.2 44.4 22.4 17.2 1.9 27.7 2.8 20.7 17.8 18.1 4.9 42.7 23.5 22.0 28.5 17.8 13.7 22.0 19.0 8.6 17.5 36.4 110.7 18.5 18.2 12.3 26.4 14.7 10.4 3.4 16.8 21.0 19.6 8.4 11.7 21.6 43.3 16.1 21.8 21.8 16.7 14.3 18.0 17.3 77.6 14.5 29.3 17.3 6.6 22.2 16.0 40.4 40.4 21.9 11.9 62.8 18.3 16.7 21.4 23.1 RPL6 "L6, TAXREB107, TXREB1" ENSG00000089009 "Ribosomal protein L6" Q02878 12 112405189-112418838 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060903, HPA068418" Approved Approved "Microtubules,Cytokinetic bridge" Yes No 620000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Microtubules, Cytokinetic bridge" "HPA060903: AB_2732653, HPA068418: AB_2685987" "unprognostic (5.95e-2)" "unprognostic (1.31e-1)" "unprognostic (1.40e-1)" "unprognostic (5.49e-2)" "unprognostic (1.10e-2)" "unprognostic (2.50e-1)" "unprognostic (1.02e-2)" "unprognostic (3.74e-1)" "unprognostic (5.63e-2)" "unprognostic (1.07e-2)" "unprognostic (4.19e-3)" "unprognostic (2.52e-2)" "prognostic unfavorable (6.95e-4)" "unprognostic (2.45e-1)" "unprognostic (2.40e-2)" "unprognostic (3.38e-2)" "unprognostic (5.90e-2)" 1199.2 1080.7 788.0 937.3 801.7 2387.8 1856.5 776.8 1063.3 1357.1 828.3 1249.1 789.1 1236.7 1570.4 1485.5 1241.3 734.2 856.8 756.3 814.1 985.6 1026.1 803.0 1847.2 805.2 807.2 2777.7 1984.2 1103.8 1049.8 763.3 801.3 1017.4 1222.4 531.8 1632.2 850.0 1451.0 1598.1 946.0 1018.7 822.2 1015.0 1214.8 279.2 808.0 1815.8 1223.2 1298.0 2204.7 1349.1 1216.0 818.0 1973.8 1887.6 2227.1 2264.4 2725.6 4486.8 2932.4 1843.2 2670.8 2471.8 1408.6 2975.9 1213.3 4225.2 1547.6 2008.9 962.8 1881.4 2395.5 3288.1 2456.2 1682.6 3199.4 2274.7 1590.4 2693.3 2854.8 4103.6 1708.4 4171.2 4542.3 1876.9 4294.7 4571.2 2818.5 2754.1 3060.8 1134.5 2888.4 2727.7 3013.0 6699.3 3096.5 4209.0 2233.7 2731.0 2375.5 4144.9 3118.1 3283.8 2050.1 2651.9 1297.5 3446.9 3342.3 2007.3 3621.2 4189.6 1657.8 1215.8 1484.2 1572.8 2110.7 1542.6 2549.7 3377.6 1573.3 2948.5 1861.4 730.3 2260.1 463.1 2285.0 1851.6 3814.8 3463.8 3465.4 2972.5 2896.3 3116.2 3751.8 3251.5 262.6 2839.0 1688.0 3372.7 3027.9 7777.8 788.0 801.7 776.8 1063.3 756.3 814.1 805.2 807.2 801.3 822.2 808.0 818.0 1483.8 798.0 1587.2 31.0 3121.1 3145.3 3907.2 3373.8 2996.4 271.4 3790.3 6493.7 262.3 1818.7 1733.0 636.4 137.6 3077.0 2809.4 731.3 3502.2 2270.2 414.6 1133.8 2774.3 1661.9 1388.1 1929.0 42.6 3043.9 4721.2 1695.5 1135.6 1287.6 1290.2 1743.7 1854.3 1727.8 1880.0 121.1 48.2 2036.2 1112.9 2566.7 2790.5 714.3 2849.7 1964.8 1899.7 30.9 3399.6 854.8 2699.3 34.7 48.9 2582.7 1646.1 1589.9 2173.6 3165.2 1095.4 3376.3 776.7 412.3 927.0 2550.9 1835.3 376.5 461.6 3977.5 3650.1 3068.7 2710.6 2783.0 2512.8 3577.6 SETX "ALS4, AOA2, KIAA0625, SCAR1, Sen1" ENSG00000107290 Senataxin Q7Z333 9 132261356-132354986 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Differentiation, DNA damage, DNA recombination, DNA repair, Neurogenesis, Spermatogenesis" "Helicase, Hydrolase" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024105, HPA057269" Approved Supported "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Cytokinetic bridge" "HPA024105: AB_2671437, HPA057269: AB_2683389" "unprognostic (2.16e-1)" "unprognostic (5.77e-2)" "unprognostic (3.23e-1)" "unprognostic (2.03e-1)" "unprognostic (9.99e-2)" "unprognostic (2.14e-2)" "unprognostic (4.86e-2)" "unprognostic (1.64e-2)" "unprognostic (2.06e-2)" "unprognostic (1.38e-2)" "unprognostic (2.36e-1)" "unprognostic (3.32e-1)" "unprognostic (6.76e-3)" "unprognostic (2.47e-1)" "unprognostic (1.13e-1)" "unprognostic (5.64e-3)" "unprognostic (6.42e-2)" 13.7 9.5 6.2 19.9 8.8 16.8 13.9 9.8 6.3 13.2 7.7 13.1 10.6 12.7 11.1 10.6 10.9 12.7 10.5 5.1 7.8 11.9 16.7 15.4 27.4 8.7 7.0 13.0 9.2 18.3 6.0 14.3 9.6 13.0 12.8 13.2 9.0 12.7 12.9 12.3 13.2 12.8 8.0 27.6 12.9 31.9 7.7 25.4 33.0 12.8 26.3 15.7 8.5 13.2 15.1 19.9 22.5 24.4 28.3 34.1 13.5 19.6 21.9 15.6 14.6 21.1 16.8 25.6 9.4 36.9 38.3 30.2 22.8 17.0 17.0 24.6 9.9 26.9 22.7 18.4 26.5 41.8 31.2 24.0 26.2 26.6 23.6 19.1 25.4 17.8 31.7 20.0 18.3 21.8 25.9 15.8 24.2 25.4 15.4 24.2 32.6 17.2 17.1 19.5 14.0 21.4 32.4 14.2 18.2 29.7 19.7 21.2 29.3 32.5 14.0 22.1 19.0 12.2 22.0 38.6 14.9 16.3 17.8 10.5 4.4 4.7 5.3 4.1 5.6 5.5 3.9 4.1 3.3 6.9 4.2 3.7 15.1 5.2 4.9 5.0 3.2 2.3 6.2 8.8 9.8 6.3 5.1 7.8 8.7 7.0 9.6 8.0 7.7 13.2 76.2 60.9 45.7 75.1 85.6 30.2 34.6 26.6 38.7 31.2 24.1 22.7 61.3 17.2 43.9 20.2 29.2 13.7 96.8 37.6 3.9 20.0 7.6 62.7 68.0 58.7 14.5 25.5 73.7 14.7 10.6 52.9 44.4 89.7 58.2 38.3 51.4 33.0 28.8 67.3 64.8 30.6 16.2 73.1 37.6 13.8 30.7 75.5 12.4 131.2 75.8 20.7 87.6 65.9 113.0 23.2 31.9 36.1 61.8 49.3 25.6 18.5 54.4 28.7 13.1 44.9 42.5 145.2 38.5 35.1 33.5 9.4 65.9 53.7 26.9 46.4 SLC29A4 "ENT4, FLJ34923" ENSG00000164638 "Solute carrier family 29 member 4" Q7RTT9 7 5274369-5306912 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 43.3;choroid plexus: 55.5" "Group enriched" "Detected in many" 5 "Enteroendocrine cells: 103.2;Horizontal cells: 168.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 49.2;SH-SY5Y: 70.7;U-2 OS: 23.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052829 Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 40: NK-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "Microtubules, Cytokinetic bridge" "HPA052829: AB_2681967" "unprognostic (6.04e-2)" "unprognostic (1.22e-2)" "unprognostic (8.49e-5)" "unprognostic (2.53e-1)" "unprognostic (1.47e-3)" "unprognostic (4.24e-2)" "unprognostic (9.59e-3)" "unprognostic (2.05e-1)" "unprognostic (2.55e-2)" "unprognostic (5.73e-2)" "prognostic favorable (4.52e-4)" "unprognostic (2.06e-1)" "unprognostic (3.02e-2)" "unprognostic (3.24e-2)" "unprognostic (2.63e-2)" "unprognostic (1.29e-3)" "unprognostic (6.60e-2)" 43.3 8.2 13.2 0.7 16.2 0.6 13.3 16.0 20.0 4.9 55.5 3.1 4.6 5.4 5.0 1.1 4.0 1.6 3.7 26.3 28.5 7.9 9.2 0.9 0.2 23.2 26.1 2.2 15.4 1.7 3.6 0.6 23.6 5.8 1.8 4.1 1.3 0.7 2.6 3.0 5.5 1.8 17.2 1.6 6.5 2.6 30.0 0.3 9.7 0.4 0.1 2.4 2.0 7.4 0.0 21.7 12.6 49.2 0.6 0.2 2.4 1.8 0.1 1.6 0.9 12.3 0.4 0.0 2.4 1.9 8.1 0.3 4.8 0.4 0.5 0.1 2.8 0.2 0.7 18.3 3.8 0.2 3.0 1.5 16.2 0.3 0.9 2.9 1.5 4.5 3.6 0.1 1.2 10.8 2.0 0.9 16.0 1.5 1.3 8.3 2.1 1.9 3.2 0.5 8.4 70.7 1.3 4.4 0.9 10.7 5.5 5.9 0.7 17.3 23.4 1.6 0.5 1.1 0.0 0.1 2.2 0.7 8.0 0.8 0.3 0.2 0.2 0.1 0.4 0.2 0.1 0.2 0.1 0.4 0.2 0.2 1.3 1.6 0.1 0.3 0.1 0.1 13.2 16.2 16.0 20.0 26.3 28.5 23.2 26.1 23.6 17.2 30.0 7.4 0.5 3.2 0.5 8.8 0.0 0.1 0.2 0.1 0.0 6.9 0.7 0.6 2.5 0.0 0.2 0.0 16.7 0.3 0.2 6.3 0.0 5.3 0.1 3.3 3.0 0.6 103.2 0.0 2.4 0.2 0.4 2.2 2.0 0.7 0.0 25.7 0.0 1.0 0.4 168.2 14.3 4.4 0.0 0.3 0.7 0.7 0.3 0.3 0.0 0.0 0.1 4.8 0.0 4.0 0.6 1.4 0.5 0.4 0.1 2.3 0.8 0.2 1.4 1.6 0.0 0.5 2.2 0.4 4.2 0.1 0.3 0.3 0.3 1.7 1.0 0.2 SNPH bA314N13.5 ENSG00000101298 Syntaphilin O15079 20 1266280-1309328 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 75.5" "Cell type enhanced" "Detected in many" "Astrocytes: 45.7;Bipolar cells: 24.3;Excitatory neurons: 60.6;Horizontal cells: 30.3;Inhibitory neurons: 71.7;Oligodendrocyte precursor cells: 38.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.0;naive CD8 T-cell: 1.0" "Lineage enriched" "Detected in single" 9 "T-cells: 1.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049393 Approved Uncertain "Cytokinetic bridge,Mitochondria" Yes No "Cluster 32: T-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "Cytokinetic bridge" "HPA049393: AB_2680744" "unprognostic (1.43e-2)" "unprognostic (2.55e-2)" "unprognostic (2.28e-1)" "unprognostic (8.84e-3)" "unprognostic (2.06e-1)" "unprognostic (1.85e-1)" "unprognostic (2.56e-2)" "unprognostic (5.33e-2)" "unprognostic (3.08e-2)" "unprognostic (3.15e-2)" "prognostic favorable (6.97e-5)" "unprognostic (1.03e-1)" "unprognostic (6.94e-3)" "unprognostic (2.45e-2)" "unprognostic (1.55e-1)" "unprognostic (2.99e-1)" "unprognostic (1.21e-1)" 1.6 3.7 47.2 1.5 49.6 0.6 1.6 7.5 75.5 4.0 0.0 8.4 1.5 6.4 1.9 1.8 6.5 2.6 7.1 54.0 19.0 2.7 0.3 2.4 1.6 38.0 19.0 2.1 3.5 4.4 12.5 0.6 38.1 5.9 0.8 12.9 6.1 11.1 7.2 1.2 4.6 4.8 7.1 1.7 5.1 3.9 33.3 0.9 5.0 1.6 0.8 4.7 3.0 44.3 2.3 7.6 0.1 6.5 7.6 4.0 0.0 4.1 5.2 4.4 2.0 0.3 0.7 0.4 2.4 4.9 10.9 1.2 1.0 5.7 0.8 1.6 1.8 4.7 1.2 0.1 4.0 0.0 7.1 2.7 2.7 4.5 0.9 4.3 5.6 4.5 0.9 0.2 4.0 0.0 0.4 0.2 2.4 0.0 5.7 0.0 1.5 0.1 5.8 3.4 0.4 2.0 4.1 0.2 5.8 0.6 0.3 0.1 9.6 7.1 5.3 6.4 1.2 0.6 1.4 0.0 3.8 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.2 0.2 0.0 0.0 1.0 1.0 0.0 0.0 0.0 0.1 0.1 0.5 47.2 49.6 7.5 75.5 54.0 19.0 38.0 19.0 38.1 7.1 33.3 44.3 0.5 0.0 0.0 45.7 0.6 0.1 0.1 2.2 1.2 24.3 2.4 0.9 4.7 4.3 1.2 3.7 6.2 0.0 2.3 0.9 0.0 0.4 10.4 0.2 0.7 1.0 8.4 0.0 60.6 0.6 0.1 1.3 5.6 0.5 0.0 2.1 2.2 0.0 0.3 30.3 71.7 1.0 2.0 0.0 0.3 5.4 1.5 0.2 0.0 9.4 0.2 2.7 1.0 38.2 1.7 1.1 1.0 4.1 0.4 1.6 0.1 1.7 1.2 20.3 6.6 2.6 1.7 1.3 0.5 0.2 0.1 0.0 1.6 1.2 1.8 0.1 TRIM45 "FLJ13181, RNF99" ENSG00000134253 "Tripartite motif containing 45" Q9H8W5 1 117111060-117122587 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 29.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Cardiomyocytes: 12.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 31.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030266, HPA054308" Uncertain Supported "Cytokinetic bridge,Cytosol" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "Cytokinetic bridge" "HPA030266: AB_10795476, HPA054308: AB_2682445" "prognostic favorable (1.58e-4)" "unprognostic (2.68e-2)" "unprognostic (1.12e-2)" "unprognostic (3.49e-1)" "unprognostic (5.70e-2)" "unprognostic (9.66e-2)" "unprognostic (2.19e-3)" "unprognostic (1.16e-2)" "unprognostic (1.26e-2)" "unprognostic (1.43e-2)" "unprognostic (3.05e-1)" "unprognostic (5.45e-2)" "unprognostic (7.09e-2)" "unprognostic (3.90e-2)" "unprognostic (4.85e-2)" "prognostic unfavorable (2.92e-4)" "unprognostic (1.27e-2)" 2.9 7.1 3.9 1.2 3.6 2.1 5.4 2.9 3.9 7.3 3.1 6.2 3.7 8.7 6.6 2.2 10.0 2.9 12.6 3.4 3.1 6.7 1.7 2.4 0.9 3.3 3.2 9.1 11.4 5.6 10.5 2.0 3.0 10.7 2.1 3.6 4.7 5.7 29.1 5.8 3.1 4.9 3.2 3.2 5.7 7.6 3.7 0.8 12.0 10.5 0.6 8.1 5.3 3.8 4.3 3.6 16.0 7.5 1.3 3.6 11.9 4.8 2.0 3.3 3.3 1.8 3.9 0.1 3.5 2.2 3.5 3.9 3.7 3.9 4.4 2.5 3.8 2.6 13.9 2.1 2.3 2.4 3.6 4.6 3.8 5.5 3.9 6.2 4.1 4.7 3.2 3.2 3.1 19.3 1.4 2.7 8.7 2.5 3.5 6.1 31.4 0.9 4.5 3.9 11.9 3.1 3.9 3.6 3.1 15.0 6.2 3.1 1.4 4.6 6.6 2.8 4.3 8.7 3.5 0.3 6.0 2.2 12.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.5 0.0 3.9 3.6 2.9 3.9 3.4 3.1 3.3 3.2 3.0 3.2 3.7 3.8 1.1 9.6 2.7 4.9 0.1 1.1 1.8 1.5 1.2 1.4 5.0 3.4 12.2 4.3 2.2 1.8 4.2 2.7 0.1 0.3 1.9 1.9 5.7 2.8 2.6 1.5 1.8 2.5 2.5 3.2 1.2 2.1 3.6 2.8 0.0 4.0 2.2 0.2 0.8 1.7 1.9 1.6 0.0 0.3 0.3 2.7 1.8 0.4 0.0 3.7 0.0 1.4 0.0 3.5 2.3 2.1 0.0 1.9 0.6 0.5 0.4 0.4 1.9 1.4 0.0 3.1 2.1 6.1 5.3 1.3 1.6 1.1 0.4 5.5 1.6 1.3 XPA "XP1, XPAC" ENSG00000136936 "XPA, DNA damage recognition and repair factor" P23025 9 97674909-97697340 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000155, HPA056856" Supported Approved "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Cytokinetic bridge" "CAB000155: , HPA056856: AB_2683258" "unprognostic (8.76e-2)" "unprognostic (1.05e-3)" "unprognostic (1.60e-1)" "unprognostic (2.30e-2)" "unprognostic (4.17e-1)" "unprognostic (1.84e-1)" "unprognostic (5.26e-2)" "unprognostic (2.38e-1)" "unprognostic (3.90e-2)" "unprognostic (1.28e-1)" "unprognostic (1.97e-3)" "unprognostic (9.55e-3)" "prognostic favorable (4.28e-5)" "unprognostic (2.19e-2)" "unprognostic (1.56e-1)" "unprognostic (3.03e-2)" "unprognostic (1.17e-1)" 15.1 13.4 9.9 9.5 10.3 9.1 13.4 12.0 15.4 13.9 10.8 23.0 15.8 14.0 11.0 14.9 13.1 9.7 9.9 9.7 10.8 18.4 18.8 11.3 14.0 10.2 10.0 13.0 11.8 18.7 9.9 9.7 9.8 14.8 9.9 10.6 12.5 12.7 19.5 12.5 13.1 12.0 9.7 12.5 21.6 5.2 10.7 11.0 23.6 8.6 17.2 15.4 13.5 10.6 35.5 8.2 11.9 14.8 14.3 13.7 8.2 9.4 14.9 16.9 11.4 21.4 28.9 19.9 8.9 10.5 11.3 17.4 9.6 11.4 14.1 13.7 19.2 15.7 17.7 12.0 15.5 18.7 18.2 12.0 12.0 7.9 8.0 11.4 19.1 16.1 22.0 15.2 9.4 11.0 24.4 22.5 8.2 33.5 13.5 24.6 25.4 17.0 27.0 13.7 16.7 16.7 13.4 10.3 12.7 9.0 14.9 11.1 12.0 5.9 14.8 23.4 20.6 26.5 22.7 12.3 14.6 13.2 11.8 12.8 21.6 22.6 25.5 23.0 30.1 34.4 27.9 25.0 23.0 40.5 33.5 29.0 2.6 35.2 29.7 39.8 33.1 19.6 9.9 10.3 12.0 15.4 9.7 10.8 10.2 10.0 9.8 9.7 10.7 10.6 32.4 25.6 37.8 49.0 36.1 17.3 23.3 39.3 31.9 101.4 24.8 31.9 36.2 45.8 39.7 22.0 81.3 32.1 47.2 10.6 121.3 36.3 1.7 22.5 29.1 30.4 22.3 11.1 49.3 38.3 9.7 31.3 22.4 17.2 30.9 28.0 28.2 48.7 36.0 84.1 63.5 24.6 30.5 27.7 20.7 4.0 44.1 24.5 14.2 40.3 49.6 87.0 64.9 74.9 96.0 29.3 19.2 47.4 26.2 18.9 32.1 55.5 28.6 97.5 32.9 38.3 39.4 18.2 17.9 28.5 18.8 14.0 34.9 36.4 24.2 23.5 ZNF302 "ZNF135L, ZNF140L, ZNF327" ENSG00000089335 "Zinc finger protein 302" Q9NR11 19 34677639-34686397 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 203.2;choroid plexus: 142.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA059503 Approved "Vesicles,Cytokinetic bridge" Yes No "Cluster 6: Non-specific - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Vesicles, Cytokinetic bridge" "HPA059503: AB_2684043" "unprognostic (3.52e-1)" "unprognostic (1.85e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (2.03e-5)" "unprognostic (2.25e-1)" "unprognostic (1.32e-2)" "unprognostic (2.78e-1)" "unprognostic (1.50e-2)" "unprognostic (4.33e-3)" "unprognostic (1.82e-2)" "unprognostic (4.63e-2)" "unprognostic (3.39e-2)" "prognostic unfavorable (5.41e-4)" "unprognostic (2.34e-1)" "unprognostic (1.21e-1)" "unprognostic (3.94e-2)" "prognostic favorable (9.85e-5)" 13.7 18.1 139.4 10.2 142.4 4.6 24.0 142.8 203.2 17.5 142.3 20.0 12.4 19.5 21.6 9.1 18.5 11.1 25.4 139.0 140.3 19.8 19.0 14.6 17.8 140.2 141.5 28.0 24.4 21.5 16.7 11.9 141.4 18.0 15.4 45.2 13.5 18.8 37.2 12.8 15.7 14.8 140.7 19.4 14.9 15.5 140.7 17.2 19.1 30.4 16.7 18.0 12.1 147.3 10.5 16.0 33.3 13.2 30.8 23.6 11.6 17.8 21.8 16.0 17.3 11.9 9.5 16.3 21.7 13.5 12.0 8.5 16.3 10.4 17.1 1.3 13.6 31.2 18.0 0.3 16.5 0.3 2.4 22.3 15.0 9.9 1.8 20.0 13.8 11.4 0.3 0.9 25.2 5.5 16.9 16.7 15.1 18.9 10.6 12.5 27.0 9.1 16.9 14.0 14.8 24.1 16.2 6.0 21.9 17.7 12.7 24.8 13.6 7.4 17.6 6.8 8.9 18.6 35.1 5.1 6.8 2.4 33.9 28.1 10.1 17.2 14.9 10.0 20.7 23.3 17.0 14.0 8.8 25.0 28.0 22.3 7.5 19.4 13.4 20.3 14.9 9.1 139.4 142.4 142.8 203.2 139.0 140.3 140.2 141.5 141.4 140.7 140.7 147.3 32.2 28.9 27.6 41.8 33.2 26.8 34.0 16.0 19.9 56.5 24.4 30.9 58.9 25.8 22.1 22.0 52.1 16.8 26.6 10.4 45.0 17.5 31.3 12.7 29.7 34.3 19.9 20.8 41.5 11.4 6.8 41.0 21.4 11.8 29.1 63.0 28.5 11.8 10.1 48.8 42.4 13.4 14.2 14.5 44.9 6.3 59.4 15.7 24.9 29.0 17.8 73.5 42.2 54.8 76.1 10.0 16.4 51.1 14.8 40.1 20.6 14.3 25.6 88.8 52.6 73.5 40.5 67.0 40.2 15.7 21.5 5.5 29.3 44.8 11.6 30.8