Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AANAT SNAT ENSG00000129673 "Aralkylamine N-acetyltransferase" Q16613 17 76453351-76470117 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Biological rhythms, Melatonin biosynthesis" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 11.0;testis: 4.7" "Cell type enriched" "Detected in some" 10 "Bipolar cells: 302.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.5;Daudi: 2.0;SCLC-21H: 3.2;U-266/70: 2.3;U-266/84: 2.7;U-698: 3.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054321 Supported Cytosol "Intracellular and membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 56: Bipolar cells - Visual perception" Cytosol "HPA054321: AB_2682449" "unprognostic (7.89e-2)" "unprognostic (2.62e-1)" "unprognostic (1.41e-1)" "unprognostic (2.44e-1)" "unprognostic (1.83e-2)" "unprognostic (2.03e-2)" "unprognostic (1.05e-2)" "unprognostic (3.09e-1)" "unprognostic (1.01e-2)" "unprognostic (3.61e-1)" "unprognostic (9.30e-2)" "unprognostic (4.19e-1)" "unprognostic (2.81e-7)" "unprognostic (1.04e-1)" "unprognostic (6.00e-2)" "unprognostic (4.47e-2)" "unprognostic (1.34e-2)" 0.1 0.2 0.7 1.6 0.7 1.2 0.0 0.8 1.1 0.1 0.2 0.1 0.1 0.1 0.1 0.3 0.2 0.7 0.1 0.9 0.9 0.3 0.0 0.2 1.5 2.1 1.7 0.2 0.2 0.0 0.3 0.0 2.0 0.1 0.0 11.0 0.1 0.0 0.1 1.4 0.4 0.0 1.2 1.0 0.2 4.7 2.1 0.0 0.4 0.0 0.1 0.2 0.1 1.4 0.5 2.5 0.3 0.2 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 1.7 2.0 0.3 0.0 0.3 0.6 0.0 0.0 0.1 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.6 0.2 0.0 1.0 0.2 0.3 0.0 0.1 0.6 0.8 0.2 0.1 0.1 1.1 0.0 0.0 3.2 0.2 0.0 0.1 0.8 0.3 1.5 0.3 0.0 0.0 0.9 0.1 0.0 2.3 2.7 3.6 0.6 0.2 0.4 0.7 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.3 0.0 0.0 0.7 0.7 0.8 1.1 0.9 0.9 2.1 1.7 2.0 1.2 2.1 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 302.1 0.1 0.4 0.3 0.0 0.0 0.0 12.5 0.3 0.2 0.0 0.0 0.0 7.5 0.2 0.1 0.6 1.2 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 6.7 0.6 0.1 0.0 0.3 0.0 19.4 0.3 0.1 0.0 0.0 0.0 13.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.4 0.0 30.2 0.0 0.0 0.0 3.1 1.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 AAR2 "bA234K24.2, C20orf4" ENSG00000131043 "AAR2 splicing factor" Q9Y312 20 36236131-36270918 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034220, HPA048645" Uncertain Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 89: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "CAB034220: AB_1564205, HPA048645: AB_2680475" "unprognostic (1.73e-1)" "unprognostic (1.30e-1)" "unprognostic (3.92e-2)" "unprognostic (1.01e-2)" "unprognostic (1.56e-1)" "unprognostic (7.54e-3)" "prognostic unfavorable (1.83e-6)" "unprognostic (5.09e-2)" "unprognostic (6.84e-2)" "unprognostic (6.38e-2)" "unprognostic (3.79e-1)" "unprognostic (3.31e-1)" "unprognostic (4.61e-3)" "unprognostic (4.58e-2)" "unprognostic (5.85e-2)" "unprognostic (1.25e-1)" "unprognostic (6.17e-2)" 22.3 26.8 14.5 14.3 15.8 22.3 21.6 15.8 15.5 19.8 19.1 27.5 15.1 25.6 25.0 17.8 23.2 16.5 18.8 14.3 14.7 20.9 23.5 19.2 17.5 15.9 15.2 22.6 18.6 25.5 10.0 17.5 15.9 19.9 17.3 7.5 18.1 21.1 23.4 25.9 18.9 27.9 15.5 18.1 23.0 16.4 15.4 26.2 17.9 20.7 19.9 25.8 16.2 17.2 26.9 30.7 28.8 33.2 48.9 32.4 22.9 25.4 33.7 58.1 45.7 69.2 35.0 18.2 35.6 36.9 44.8 36.6 46.6 48.2 35.8 17.0 28.2 57.9 19.3 43.3 36.9 39.5 27.9 39.6 68.7 41.5 31.5 29.4 36.3 36.0 36.8 34.3 32.4 32.0 56.0 48.9 25.1 39.1 49.5 30.7 48.3 42.4 33.0 19.6 33.2 36.1 37.8 100.7 32.8 26.2 57.1 42.8 26.6 54.9 34.3 33.0 32.2 31.1 42.3 34.6 39.9 26.3 29.7 60.6 46.2 41.6 43.0 49.4 43.2 32.5 40.0 41.4 49.1 35.5 50.0 43.0 8.9 58.4 58.1 39.8 50.2 57.4 14.5 15.8 15.8 15.5 14.3 14.7 15.9 15.2 15.9 15.5 15.4 17.2 11.7 6.4 12.5 4.6 10.8 5.7 10.6 11.8 6.8 4.4 10.3 9.5 6.8 11.5 8.4 9.2 8.4 21.3 10.9 7.1 11.7 19.7 2.8 6.9 8.9 11.9 11.4 14.7 6.3 21.0 14.3 12.7 6.6 6.6 15.9 10.8 11.4 11.8 15.0 15.2 7.1 10.5 12.2 15.0 2.5 3.1 11.1 8.5 10.6 3.7 12.3 6.1 14.4 5.0 9.9 17.3 7.6 15.1 7.5 11.3 8.4 8.0 11.1 3.5 6.6 9.8 13.9 17.0 14.5 9.0 7.5 18.6 7.9 15.3 8.7 8.9 AARS1 "AARS, AlaRS, CMT2N" ENSG00000090861 "Alanyl-tRNA synthetase 1" P49588 16 70251983-70289707 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Charcot-Marie-Tooth disease, Disease variant, Epilepsy, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Cardiomyocytes: 25.1;Cytotrophoblasts: 63.0;Extravillous trophoblasts: 29.9;Hofbauer cells: 27.1;Syncytiotrophoblasts: 52.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034261, HPA040870, HPA044223" Supported Supported Cytosol NA NA 620000 "Cluster 27: Non-specific - Gene expression" "Cluster 22: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "CAB034261: AB_1562673, HPA040870: AB_10794995, HPA044223: AB_2678862" "unprognostic (1.98e-2)" "unprognostic (6.87e-2)" "unprognostic (8.02e-2)" "unprognostic (5.72e-2)" "unprognostic (3.58e-1)" "unprognostic (2.50e-2)" "unprognostic (7.99e-2)" "unprognostic (2.36e-1)" "unprognostic (1.99e-1)" "unprognostic (1.76e-1)" "unprognostic (8.33e-2)" "unprognostic (2.92e-1)" "unprognostic (3.42e-2)" "unprognostic (3.75e-2)" "unprognostic (2.05e-3)" "unprognostic (8.22e-2)" "unprognostic (3.83e-3)" 43.7 54.7 60.1 33.4 64.3 7.9 41.4 73.3 88.6 42.1 49.2 48.9 26.0 49.8 49.6 29.5 40.4 22.3 47.9 62.8 71.7 43.6 72.0 45.3 30.0 78.6 68.6 37.3 75.8 74.9 50.1 35.6 84.9 40.0 26.2 59.3 53.3 47.2 62.4 28.8 32.7 47.8 66.3 38.3 51.8 23.8 74.8 36.4 66.6 39.7 35.5 45.9 32.8 83.9 123.7 192.8 52.9 205.7 127.3 115.0 125.7 97.7 135.3 119.7 151.8 162.5 163.2 140.4 127.2 99.3 90.8 137.2 160.5 133.1 170.7 63.2 54.7 135.6 78.0 152.2 348.0 74.4 77.2 133.9 193.8 228.1 508.4 91.4 120.3 209.3 176.0 173.4 91.3 282.0 89.4 85.0 104.3 160.0 108.5 170.4 36.1 317.0 84.7 60.3 67.9 57.3 269.5 62.3 246.1 75.8 197.7 181.3 75.2 85.2 82.9 84.9 78.8 233.8 174.2 258.2 155.4 124.9 175.9 6.5 7.8 2.7 11.9 13.2 13.0 12.8 9.7 11.7 11.9 9.1 11.2 12.2 0.1 22.7 14.1 7.0 8.0 12.6 60.1 64.3 73.3 88.6 62.8 71.7 78.6 68.6 84.9 66.3 74.8 83.9 6.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.1 0.0 0.0 0.0 0.0 63.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 29.9 4.5 0.0 0.0 0.0 0.0 0.0 0.0 27.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 52.0 0.2 0.0 0.0 0.0 ABCA4 "ABCR, ARMD2, CORD3, FFM, RP19, STGD, STGD1" ENSG00000198691 "ATP binding cassette subfamily A member 4" P78363 1 93992834-94121148 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Transport, Vision" Translocase "Age-related macular degeneration, Cone-rod dystrophy, Disease variant, Retinitis pigmentosa, Stargardt disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 32 "choroid plexus: 144.6;retina: 461.0" "Group enriched" "Detected in some" 12 "Cone photoreceptor cells: 450.4;Rod photoreceptor cells: 482.9" "Cancer enhanced" "Detected in many" "lung cancer: 3.1" "Region enriched" "Detected in some" 6 "hippocampal formation: 9.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.1;EFO-21: 6.8;HeLa: 2.3;SK-BR-3: 3.0;SuSa: 3.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA064420, HPA078826" Enhanced Approved Cytosol NA NA "Cluster 79: Retina - Phototransduction" "Cluster 38: EFO-21 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol "HPA064420: , HPA078826: " "unprognostic (1.25e-1)" "unprognostic (3.93e-1)" "unprognostic (3.29e-2)" "unprognostic (7.17e-4)" "unprognostic (1.28e-1)" "unprognostic (3.00e-1)" "unprognostic (1.38e-2)" "prognostic favorable (2.45e-4)" "unprognostic (3.77e-2)" "unprognostic (5.25e-1)" "unprognostic (3.70e-1)" "unprognostic (5.18e-2)" "unprognostic (1.17e-9)" "unprognostic (1.61e-2)" "unprognostic (1.55e-1)" "unprognostic (2.47e-1)" "prognostic unfavorable (2.72e-4)" 0.5 0.0 0.4 0.1 0.3 0.0 0.8 1.1 0.7 0.5 144.6 0.2 2.5 0.1 8.4 0.2 0.4 0.1 0.2 9.3 0.1 8.7 0.9 0.3 0.4 0.4 0.5 0.2 0.0 0.0 0.1 0.6 0.2 0.2 0.1 461.0 0.0 1.4 0.1 2.1 2.9 0.0 0.1 0.1 0.1 1.0 1.4 0.3 0.4 0.0 0.1 0.2 0.1 0.4 0.3 0.0 0.1 0.0 0.0 0.0 3.1 0.1 0.2 0.0 0.1 0.1 0.0 0.0 6.8 0.3 0.1 0.7 0.0 0.0 0.1 0.0 0.0 0.4 2.3 0.7 0.4 0.0 0.0 0.3 0.0 0.3 0.0 0.1 0.6 0.0 0.0 0.1 0.0 0.9 0.5 0.0 1.2 0.0 0.1 0.1 0.2 0.2 0.3 0.3 0.0 0.0 0.6 3.0 0.1 3.1 0.3 0.0 0.1 0.2 1.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 1.1 0.7 9.3 0.1 0.4 0.5 0.2 0.1 1.4 0.4 1.2 0.0 1.1 1.3 0.0 0.1 0.2 1.7 0.0 27.9 0.5 1.3 1.1 0.0 1.8 7.3 450.4 0.3 0.0 0.0 0.0 0.0 8.8 0.3 0.1 3.1 0.0 0.0 0.4 0.0 1.5 0.2 0.0 0.9 0.0 0.2 1.4 0.3 0.1 10.1 0.6 16.2 0.0 0.3 0.0 21.9 0.0 0.0 0.0 19.7 0.0 37.3 0.0 0.5 0.0 0.0 0.0 0.4 0.0 2.6 1.3 0.4 2.3 482.9 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.3 0.0 0.3 0.6 0.7 ABCE1 "OABP, RLI, RLI1, RNASEL1, RNASELI, RNS4I" ENSG00000164163 "ATP binding cassette subfamily E member 1" P61221 4 145098288-145129524 "Predicted intracellular proteins, Transporters" "Host-virus interaction, Translation regulation" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012476, HPA036846" Approved Enhanced Cytosol No No 380000 "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "CAB012476: , HPA036846: AB_2675346" "unprognostic (2.22e-3)" "unprognostic (8.11e-3)" "prognostic favorable (8.69e-4)" "unprognostic (2.69e-1)" "unprognostic (1.06e-1)" "unprognostic (5.51e-3)" "prognostic unfavorable (6.29e-4)" "unprognostic (5.68e-3)" "unprognostic (6.77e-2)" "unprognostic (1.34e-1)" "prognostic unfavorable (1.88e-4)" "unprognostic (1.56e-2)" "unprognostic (1.38e-3)" "unprognostic (2.85e-1)" "unprognostic (2.40e-1)" "unprognostic (2.08e-2)" "unprognostic (2.21e-1)" 30.0 21.5 11.2 33.6 12.5 27.2 33.1 13.7 16.0 20.7 10.7 22.7 20.2 24.4 16.0 35.1 22.5 22.4 24.9 12.5 14.3 23.8 39.7 18.5 40.5 12.6 11.2 29.1 29.4 27.0 10.0 28.7 14.4 19.4 27.7 14.4 24.1 16.9 28.0 25.2 17.7 28.9 13.8 26.4 20.1 26.5 11.8 34.2 26.9 30.3 42.1 40.5 15.9 18.1 117.1 61.2 89.5 62.2 74.6 107.5 89.4 124.6 86.4 145.1 101.3 95.5 105.9 187.6 39.3 109.2 77.7 75.4 132.5 157.7 193.1 108.6 82.9 106.9 44.0 80.6 98.3 244.3 81.3 80.0 108.4 153.8 213.7 74.8 157.4 139.1 219.5 136.1 156.3 70.4 234.5 82.2 74.8 177.5 142.9 124.0 107.9 135.7 108.1 79.9 111.1 55.1 74.7 124.6 89.5 66.7 74.2 98.1 105.3 143.3 89.4 101.3 152.5 120.6 209.6 199.5 87.7 214.6 163.7 2.2 10.0 0.9 12.3 13.1 25.4 13.2 15.4 16.0 19.5 13.0 21.0 18.1 0.8 16.4 13.4 10.9 18.5 14.8 11.2 12.5 13.7 16.0 12.5 14.3 12.6 11.2 14.4 13.8 11.8 18.1 56.4 25.6 18.7 15.3 55.9 59.9 109.0 38.7 45.5 37.2 35.0 30.6 24.0 17.2 45.4 25.8 20.9 39.4 44.4 9.8 39.2 39.4 40.1 29.0 61.8 53.7 20.4 47.5 24.2 28.2 45.1 50.6 35.7 23.4 32.9 50.3 21.4 32.9 41.5 42.1 27.8 22.5 24.4 22.4 40.3 15.4 46.9 34.6 19.6 12.2 33.2 18.1 33.0 18.1 37.5 39.1 10.3 34.6 58.3 112.2 8.0 39.8 28.5 34.9 32.9 71.7 47.5 92.4 79.4 65.5 59.5 26.5 47.2 98.4 36.6 72.2 ABCF1 "ABC50, EST123147" ENSG00000204574 "ATP binding cassette subfamily F member 1" Q8NE71 6 30571393-30597179 "Plasma proteins, Predicted intracellular proteins, Transporters" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 107.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017578 Approved Enhanced Cytosol NA NA 490000 "Cluster 39: Non-specific - mRNA processing" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Cytosol "HPA017578: AB_1844438" "unprognostic (5.85e-2)" "unprognostic (2.88e-1)" "unprognostic (1.49e-1)" "unprognostic (1.41e-3)" "unprognostic (4.31e-2)" "unprognostic (7.03e-2)" "prognostic unfavorable (9.47e-4)" "unprognostic (5.50e-2)" "unprognostic (3.45e-2)" "unprognostic (1.70e-2)" "unprognostic (2.35e-1)" "unprognostic (2.77e-1)" "unprognostic (3.50e-2)" "unprognostic (1.65e-1)" "unprognostic (3.65e-1)" "unprognostic (1.68e-3)" "unprognostic (7.16e-2)" 31.6 27.5 4.5 6.7 5.0 25.5 28.3 4.4 6.4 29.6 3.5 34.0 2.0 34.3 7.4 32.4 24.6 6.8 35.0 4.3 4.9 28.1 32.6 29.9 7.4 5.1 4.8 26.2 32.7 13.5 24.7 10.5 5.0 28.3 11.4 11.1 30.4 5.4 107.0 39.9 32.3 10.2 4.5 30.7 32.4 35.0 5.3 14.7 29.3 4.1 11.3 32.4 30.0 5.6 46.2 33.5 29.4 39.7 40.0 24.5 4.2 30.1 37.6 49.0 53.6 104.8 16.4 33.8 27.1 34.3 51.9 33.3 61.7 39.5 56.2 34.2 65.2 43.0 47.6 14.5 5.5 9.4 5.6 33.6 33.7 68.6 6.4 4.0 5.6 16.9 77.2 4.5 35.3 8.5 9.3 15.5 7.5 31.2 9.4 64.5 7.5 63.3 32.2 52.4 10.2 42.9 20.1 55.3 6.6 5.0 6.1 24.4 28.2 59.0 6.9 3.8 6.2 35.7 47.5 52.8 1.3 43.3 62.2 1.7 5.5 1.5 10.1 4.7 9.3 6.2 7.2 10.2 4.7 5.1 6.3 6.3 1.8 8.0 4.9 5.4 4.1 6.1 4.5 5.0 4.4 6.4 4.3 4.9 5.1 4.8 5.0 4.5 5.3 5.6 42.5 51.3 84.4 7.2 67.9 86.2 100.3 54.2 49.5 48.9 45.5 30.1 87.3 42.9 65.2 58.8 66.7 100.3 77.5 103.3 60.7 93.9 105.0 67.0 95.4 57.2 50.7 50.9 6.8 87.6 139.4 52.6 53.5 115.2 86.9 27.0 36.0 125.4 49.5 55.5 7.4 80.6 28.5 47.4 43.0 176.4 38.8 52.1 35.6 2.8 63.2 39.3 116.4 2.0 9.2 105.9 73.8 51.9 61.8 92.1 66.2 99.0 44.0 112.9 72.3 58.7 54.3 132.5 104.2 50.2 84.8 166.1 70.5 48.2 72.3 87.1 ABCF2 "ABC28, EST133090, HUSSY-18, M-ABC1" ENSG00000033050 "ATP binding cassette subfamily F member 2" Q9UG63 7 151211484-151227205 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 55.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA020091, CAB020682, HPA021815, HPA030388" Approved Enhanced Cytosol NA NA 51000 "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "CAB020682: , HPA020091: AB_1844439, HPA021815: AB_1844440, HPA030388: AB_10601558" "unprognostic (6.80e-2)" "unprognostic (4.23e-1)" "unprognostic (1.38e-1)" "unprognostic (9.07e-2)" "unprognostic (1.41e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (9.52e-6)" "unprognostic (1.52e-1)" "unprognostic (8.68e-2)" "unprognostic (1.73e-1)" "unprognostic (6.31e-2)" "unprognostic (5.58e-2)" "unprognostic (9.93e-2)" "unprognostic (1.16e-2)" "unprognostic (1.95e-1)" "unprognostic (6.07e-2)" "unprognostic (7.84e-3)" 19.0 18.8 16.1 11.1 16.2 7.6 14.8 15.1 19.5 13.8 14.2 18.8 6.0 16.6 12.1 19.2 14.4 8.9 27.9 16.0 16.7 20.2 12.3 14.6 11.6 18.0 16.5 15.0 15.0 14.3 17.0 10.3 17.3 16.1 10.8 10.8 14.2 10.2 61.2 16.3 13.4 14.1 16.2 15.6 16.6 18.7 16.5 11.5 13.8 20.2 15.2 19.5 13.9 16.9 33.0 50.3 18.8 66.0 36.6 31.1 25.1 40.6 33.0 49.9 42.1 47.9 22.1 57.4 34.3 42.8 40.9 25.2 58.9 47.8 49.5 28.1 48.8 23.1 26.3 27.4 43.3 58.0 35.7 42.3 39.6 54.6 34.4 21.2 40.7 32.5 68.4 22.9 43.2 80.1 60.4 70.3 46.8 37.6 54.5 40.3 30.1 50.5 35.4 24.0 32.9 31.0 39.5 37.5 26.8 19.5 16.2 29.0 40.7 31.7 12.8 39.6 61.7 46.9 54.5 42.7 43.5 56.4 60.3 7.9 11.3 3.8 13.8 13.3 19.5 11.9 14.2 13.7 13.1 13.1 13.3 13.8 1.6 14.5 15.1 9.8 15.8 14.7 16.1 16.2 15.1 19.5 16.0 16.7 18.0 16.5 17.3 16.2 16.5 16.9 4.7 0.0 0.5 10.1 15.9 27.1 25.9 22.5 14.2 17.4 0.3 0.6 23.5 7.2 9.5 0.0 8.4 29.5 10.0 28.4 0.0 0.0 47.0 0.1 0.1 12.8 6.7 18.3 12.6 0.0 28.8 13.8 16.3 0.0 10.2 0.0 12.5 12.9 20.7 10.1 12.6 9.1 12.2 10.4 11.5 55.9 10.5 6.7 19.6 7.5 6.2 14.1 14.4 7.1 10.4 0.0 18.9 14.7 14.0 29.8 15.7 0.0 6.6 16.9 13.1 25.7 15.1 31.0 12.4 21.5 25.1 32.3 10.9 0.1 15.1 19.6 ABCF2-H2BE1 ENSG00000285292 "ABCF2-H2BE1 readthrough" Q9UG63 7 151207837-151227166 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA020091, HPA021815, HPA030388" Approved Uncertain Cytosol NA NA 51000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA020091: AB_1844439, HPA021815: AB_1844440, HPA030388: AB_10601558" 12.0 8.1 1.1 11.1 1.6 5.5 9.0 2.1 6.2 7.4 2.9 9.5 6.7 8.4 2.9 10.1 9.0 7.6 9.8 1.5 2.0 9.7 7.4 8.6 11.4 1.5 1.6 6.0 4.6 13.9 8.3 2.3 7.2 10.3 10.0 5.4 9.5 30.7 9.0 5.7 11.9 1.9 9.5 6.0 6.8 2.1 10.2 9.5 20.9 13.8 14.4 2.8 45.0 54.8 27.0 71.0 38.7 38.6 22.4 57.1 38.5 43.7 45.1 40.5 33.8 66.4 44.1 59.7 61.1 34.7 57.9 55.3 61.0 29.9 31.8 37.1 30.6 26.6 57.8 76.5 25.8 40.8 40.8 72.5 50.5 28.6 55.4 35.8 89.1 28.4 57.6 68.1 88.9 23.1 36.5 58.4 50.1 36.5 34.6 68.3 21.9 33.8 21.9 34.8 59.5 44.0 30.3 25.1 21.2 33.9 47.5 33.4 11.4 45.2 73.6 41.6 47.5 64.7 55.4 64.7 49.0 22.5 21.3 6.0 22.5 19.1 45.7 17.5 27.9 26.3 24.8 19.9 24.8 24.3 1.6 25.5 18.5 15.4 30.2 30.3 1.1 1.6 2.1 6.2 1.5 2.0 1.5 1.6 2.3 1.9 2.1 2.8 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ABHD13 "bA153I24.2, BEM46L1, C13orf6, FLJ14906" ENSG00000139826 "Abhydrolase domain containing 13" Q7L211 13 108218392-108234243 "Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032143, HPA032144" Approved Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 43: THP-1 - Innate immune response" "Cluster 28: Keratinocytes - Keratinization" Cytosol "HPA032143: AB_2674178, HPA032144: AB_10602304" "unprognostic (2.69e-1)" "unprognostic (2.81e-1)" "unprognostic (1.36e-2)" "unprognostic (2.91e-2)" "unprognostic (8.36e-2)" "unprognostic (1.48e-2)" "unprognostic (1.99e-1)" "unprognostic (2.63e-1)" "unprognostic (8.75e-2)" "unprognostic (1.79e-1)" "unprognostic (1.92e-1)" "unprognostic (6.21e-2)" "unprognostic (1.14e-1)" "unprognostic (2.73e-2)" "unprognostic (1.61e-1)" "unprognostic (1.14e-1)" "unprognostic (5.62e-2)" 7.0 5.3 3.7 7.0 4.0 16.3 7.3 5.9 5.3 6.2 7.0 6.5 7.0 6.3 10.2 5.6 4.3 6.4 4.3 4.1 3.2 6.1 10.4 6.9 8.3 3.3 3.3 5.2 4.7 5.7 3.8 8.4 3.2 6.2 7.3 6.4 4.6 5.6 4.2 4.3 7.4 6.8 3.2 7.8 6.8 3.8 3.4 9.3 7.6 6.4 7.1 7.5 4.3 3.9 9.8 4.0 10.5 5.9 8.0 9.5 5.1 9.5 9.5 8.2 9.7 6.2 9.1 8.2 9.7 7.4 8.1 8.8 7.9 11.0 13.0 11.1 6.9 10.1 5.7 6.1 8.0 21.1 12.0 9.8 10.3 6.4 8.3 7.7 9.8 11.2 5.5 4.5 8.5 4.1 10.3 8.8 5.0 14.5 4.7 8.7 7.5 4.8 11.5 8.7 7.9 9.9 5.0 8.3 10.6 9.3 7.7 19.3 10.2 5.8 6.0 6.8 6.5 8.8 7.4 9.0 13.7 13.0 10.7 7.7 8.2 16.0 5.9 7.6 8.8 6.8 8.0 7.2 7.2 6.0 7.6 6.3 9.0 9.5 7.2 5.3 8.4 8.6 3.7 4.0 5.9 5.3 4.1 3.2 3.3 3.3 3.2 3.2 3.4 3.9 17.6 22.4 16.6 8.1 24.5 44.4 21.4 33.3 15.9 12.8 16.8 10.8 7.2 27.1 22.2 11.0 0.0 20.9 23.7 14.7 9.8 19.1 24.8 12.3 13.4 18.2 30.5 16.2 21.4 21.0 15.4 19.9 19.9 14.4 14.0 9.5 19.6 29.5 19.5 18.5 17.4 11.6 44.7 21.5 40.1 18.2 15.5 24.6 26.6 15.0 25.8 12.6 19.6 16.1 15.2 20.8 14.3 17.3 10.2 20.7 16.4 11.5 18.4 12.2 19.7 15.1 18.2 22.9 12.3 21.1 51.1 21.3 28.4 12.5 12.1 26.3 ABLIM1 "ABLIM, LIMAB1, limatin" ENSG00000099204 "Actin binding LIM protein 1" O14639 10 114431113-114768061 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 875.6;Cardiomyocytes: 592.5;Peritubular cells: 413.0;Squamous epithelial cells: 481.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 139.1" "Group enriched" "Detected in many" 7 "B-cells: 52.2;NK-cells: 63.6;T-cells: 139.1" "Cell line enhanced" "Detected in many" "hTCEpi: 164.1;OE19: 159.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038951, HPA038952" Approved Supported Cytosol NA NA 6000 "Cluster 32: T-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA038951: AB_10673017, HPA038952: AB_10670915" "unprognostic (2.25e-2)" "unprognostic (3.96e-2)" "unprognostic (2.91e-1)" "unprognostic (1.26e-1)" "unprognostic (5.89e-3)" "unprognostic (1.07e-2)" "unprognostic (3.19e-2)" "unprognostic (5.07e-2)" "unprognostic (4.39e-2)" "unprognostic (1.05e-1)" "unprognostic (3.20e-2)" "unprognostic (3.23e-1)" "prognostic favorable (2.72e-5)" "unprognostic (2.77e-2)" "unprognostic (1.92e-1)" "unprognostic (3.22e-1)" "unprognostic (5.87e-2)" 73.3 93.4 71.0 35.7 67.6 13.6 54.8 277.3 59.4 44.4 76.2 46.7 37.3 37.3 26.7 205.6 51.3 33.5 268.6 58.5 78.3 54.7 28.3 54.5 50.0 90.5 65.1 233.6 32.1 42.3 22.0 31.5 74.9 24.0 57.8 110.1 98.2 26.5 75.1 97.5 34.2 29.3 85.2 20.1 120.7 41.3 67.0 56.8 112.9 111.6 89.1 42.0 89.4 73.2 48.2 34.7 120.2 27.2 1.1 0.4 1.5 9.6 3.2 2.4 6.7 49.0 76.7 61.8 128.7 11.1 18.1 101.4 41.1 66.2 3.1 21.2 35.5 0.5 96.0 128.8 0.5 24.6 0.4 1.5 164.1 18.1 52.1 50.3 47.5 21.4 0.2 93.3 0.5 17.5 5.0 10.8 47.0 159.5 38.4 2.1 29.3 80.3 38.4 105.6 41.7 51.4 40.4 59.2 21.0 60.0 30.7 0.3 32.1 0.1 43.1 1.1 18.3 0.5 0.3 140.0 2.3 54.0 0.9 11.9 0.2 0.8 28.6 0.2 55.5 40.9 53.9 32.8 0.4 52.2 139.1 91.0 2.4 63.6 0.3 0.4 33.7 48.1 71.0 67.6 277.3 59.4 58.5 78.3 90.5 65.1 74.9 85.2 67.0 73.2 218.9 317.3 36.0 875.6 47.1 86.8 42.2 35.7 306.2 54.5 27.6 29.5 592.5 51.5 97.1 53.3 18.8 1.5 43.2 59.8 35.2 37.8 110.7 88.4 32.7 107.3 16.8 7.4 236.0 54.5 0.8 126.1 225.3 30.9 1.3 119.6 55.6 51.4 0.6 58.9 326.0 101.7 16.2 1.3 18.4 133.7 227.7 9.4 21.4 213.6 4.3 54.7 27.8 50.3 9.2 59.6 34.7 413.0 22.7 49.8 46.7 42.1 79.3 96.7 0.0 155.8 22.0 3.9 4.7 481.0 189.4 0.7 62.8 53.6 51.4 164.0 ABRAXAS2 "ABRO1, Em:AC068896.4, FAM175B, KIAA0157" ENSG00000165660 "Abraxas 2, BRISC complex subunit" Q15018 10 124801819-124836667 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 25.6;Collecting duct cells: 23.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037591, HPA037592, HPA074089" Approved Supported Cytosol Yes No "Cluster 41: Basophils - Cellular respiration" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA037591: AB_10671877, HPA037592: AB_2675566, HPA074089: AB_2686659" "unprognostic (2.78e-1)" "unprognostic (1.63e-1)" "unprognostic (1.66e-1)" "unprognostic (6.47e-2)" "unprognostic (1.08e-1)" "unprognostic (3.51e-2)" "unprognostic (5.52e-2)" "unprognostic (2.19e-1)" "unprognostic (2.99e-1)" "unprognostic (6.81e-2)" "unprognostic (3.72e-2)" "unprognostic (2.09e-2)" "unprognostic (1.80e-3)" "unprognostic (3.09e-2)" "unprognostic (1.58e-1)" "unprognostic (1.42e-1)" "unprognostic (1.66e-1)" 9.1 10.5 8.0 10.3 8.3 12.3 12.2 8.0 9.9 8.8 6.6 9.9 10.2 9.4 9.3 9.8 9.0 8.2 10.0 8.4 8.6 12.3 13.7 9.3 12.5 7.8 8.4 10.4 8.3 12.7 3.9 10.3 8.5 9.5 10.3 5.3 8.5 8.8 19.0 11.6 10.8 10.5 7.7 10.0 9.5 6.7 8.2 12.9 12.7 16.2 13.3 9.7 6.8 7.9 22.2 14.9 15.7 21.6 19.9 19.6 13.5 22.4 35.1 26.2 24.1 12.1 20.9 24.7 18.6 24.4 14.2 24.4 25.0 21.0 27.5 21.6 17.2 18.8 11.8 15.0 25.4 32.6 18.9 21.6 25.1 25.8 46.4 28.3 20.1 21.7 20.0 16.6 21.6 14.5 25.1 29.1 13.5 20.0 13.8 20.0 16.6 15.1 19.5 11.1 10.8 19.8 17.9 17.0 24.4 15.8 14.0 22.2 17.4 14.0 11.2 16.5 27.1 17.2 17.1 23.6 18.3 15.9 10.1 22.8 10.5 9.8 7.6 14.5 10.5 10.5 8.8 10.6 12.9 11.6 9.3 10.3 4.1 7.7 11.8 8.7 11.4 7.0 8.0 8.3 8.0 9.9 8.4 8.6 7.8 8.4 8.5 7.7 8.2 7.9 15.1 25.6 14.3 0.0 3.5 0.0 0.0 0.0 0.0 0.0 9.4 10.3 0.0 0.0 6.2 23.9 0.0 16.9 7.0 0.0 17.6 13.7 0.0 11.1 15.6 6.3 0.0 0.0 0.0 12.5 13.0 5.5 0.0 12.3 12.6 12.4 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 20.7 0.0 0.0 0.0 0.0 10.2 0.0 0.0 1.6 0.0 0.0 18.6 12.4 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 16.0 4.3 13.5 0.0 0.0 AC008687.1 ENSG00000267335 "Novel protein" 19 49022953-49036895 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "pituitary gland: 17.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 1.6;HMC-1: 4.4;U-138 MG: 1.6;U-251 MG: 6.0" HPA038925 Uncertain Approved Cytosol "Secreted - unknown location" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" Cytosol "HPA038925: AB_2676272" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.7 0.0 17.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.6 0.1 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.6 0.0 0.2 0.0 0.0 1.6 1.3 0.3 6.0 0.3 1.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.5 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 AC011005.1 ENSG00000230626 "Novel protein similar to mitogen-activated protein kinase kinase 2 MAP2K2" 7 129126518-129130793 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 3.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051993 Uncertain Approved Cytosol NA NA "Cluster 71: Testis - DNA repair" Cytosol "HPA051993: AB_2681685" "unprognostic (2.03e-1)" "unprognostic (7.97e-2)" "unprognostic (8.08e-2)" "unprognostic (2.28e-3)" "unprognostic (1.58e-1)" "unprognostic (2.67e-3)" "unprognostic (1.35e-2)" "unprognostic (1.14e-1)" "unprognostic (1.14e-1)" "unprognostic (1.13e-1)" "unprognostic (3.11e-2)" "unprognostic (3.61e-1)" "unprognostic (2.60e-2)" "unprognostic (3.01e-1)" "unprognostic (1.06e-1)" "unprognostic (4.36e-5)" "unprognostic (3.43e-2)" 0.3 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.3 0.0 0.4 0.0 0.3 0.0 0.5 0.2 0.0 0.7 0.0 0.0 0.3 0.4 0.3 0.0 0.0 0.0 0.3 0.5 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.3 0.0 1.4 0.4 0.4 0.0 0.0 0.3 0.4 3.1 0.0 0.0 0.3 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC012488.2 ENSG00000286165 "Novel protein" 2 189661519-189667881 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "brain: 2.7" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "cerebral cortex: 2.7" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "A549: 1.2;HDLM-2: 1.2" HPA075042 Approved Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" Cytosol "HPA075042: AB_2686731" 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.2 2.7 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 1.2 0.8 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.3 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.4 0.7 1.1 0.4 0.4 0.3 1.3 0.4 0.0 0.2 2.1 0.3 0.2 0.5 0.6 0.2 1.0 2.3 0.4 0.2 0.3 0.2 2.7 0.2 0.2 0.3 0.1 0.4 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC117378.1 ENSG00000285625 "Novel protein" 12 56714612-56741535 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.2;skeletal muscle: 3.6" "Cell type enhanced" "Detected in single" "Alveolar cells type 2: 1.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 17.4;REH: 18.1" HPA073152 Approved Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" Cytosol "HPA073152: AB_2686575" 0.4 0.5 1.3 1.7 1.5 2.0 0.5 1.9 3.2 0.3 1.0 0.8 0.3 0.7 0.0 0.5 0.4 0.0 0.1 1.2 1.3 0.2 0.8 0.6 0.2 1.4 1.4 0.3 2.6 0.0 0.2 1.6 0.3 0.4 2.7 0.0 0.3 3.6 0.2 0.5 0.2 1.1 0.6 0.2 0.5 1.5 1.9 0.2 0.0 0.7 0.4 1.9 5.6 1.3 3.7 2.2 1.3 0.0 4.0 3.6 0.6 2.0 1.4 0.0 2.9 2.6 5.8 0.5 1.5 8.9 2.2 1.0 1.0 3.8 1.5 6.2 1.3 0.7 0.9 15.8 10.3 0.9 1.4 2.0 2.2 2.5 0.5 8.5 3.0 5.4 2.8 2.6 17.4 9.9 9.3 4.6 1.4 18.1 4.4 2.0 2.6 1.3 3.7 0.6 1.3 0.0 6.6 1.0 1.7 11.3 1.5 1.0 15.3 4.8 5.4 15.1 8.9 4.6 1.7 5.6 1.5 2.6 1.8 3.8 7.2 4.8 9.4 10.7 11.7 8.8 3.7 12.1 13.3 11.0 0.0 6.1 6.3 5.0 12.4 4.9 1.3 1.5 1.9 3.2 1.2 1.3 1.4 1.4 1.6 1.1 1.5 1.9 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 ACCSL ENSG00000205126 "1-aminocyclopropane-1-carboxylate synthase homolog (inactive) like" Q4AC99 11 44047981-44059977 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Astrocytes: 2.0;Excitatory neurons: 2.6;Inhibitory neurons: 2.7;Oligodendrocyte precursor cells: 2.5;Oligodendrocytes: 1.8" "Cancer enriched" "Detected in single" 22 "melanoma: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA065042 Approved Cytosol NA NA "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA065042: " "unprognostic (2.37e-2)" "unprognostic (2.91e-1)" "unprognostic (9.76e-5)" "unprognostic (7.42e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACMSD ENSG00000153086 "Aminocarboxymuconate semialdehyde decarboxylase" Q8TDX5 2 134838616-134902034 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "kidney: 141.1;liver: 162.5" "Group enriched" "Detected in some" 4 "Hepatocytes: 120.2;Proximal tubular cells: 408.1" "Group enriched" "Detected in some" 23 "liver cancer: 21.2;renal cancer: 19.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 21 "RPTEC TERT1: 26.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA010533, HPA011179" Enhanced Approved Cytosol NA NA 12000 "Cluster 37: B-cells - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA010533: AB_1844517, HPA011179: AB_1844516" "unprognostic (1.06e-2)" "unprognostic (5.30e-2)" "unprognostic (1.40e-1)" "unprognostic (7.50e-2)" "unprognostic (3.79e-2)" "unprognostic (1.36e-2)" "unprognostic (4.40e-3)" "unprognostic (1.15e-1)" "unprognostic (5.35e-4)" "unprognostic (7.60e-2)" "unprognostic (5.17e-2)" "unprognostic (2.44e-3)" "prognostic favorable (2.39e-4)" "unprognostic (1.26e-1)" "unprognostic (1.70e-1)" "unprognostic (2.93e-2)" "unprognostic (2.65e-5)" 0.0 0.2 0.1 0.1 0.0 0.2 0.1 0.9 0.3 0.0 0.0 0.1 0.9 0.1 0.0 0.0 0.0 7.1 0.2 0.0 0.3 141.1 162.5 0.1 0.3 0.8 0.2 0.7 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.4 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.6 0.4 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.4 0.1 1.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.7 0.4 0.1 0.8 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.4 0.6 0.0 0.0 0.3 0.8 0.3 1.2 0.2 0.5 0.1 0.6 0.3 26.7 0.4 1.0 0.3 0.1 0.3 0.4 0.8 0.2 0.7 1.0 0.0 0.4 0.2 0.8 0.2 0.1 0.5 0.2 0.3 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.9 0.3 0.0 0.3 0.8 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.2 50.1 0.0 9.2 0.0 0.0 0.0 0.0 54.8 0.2 0.0 0.0 0.1 0.0 0.0 2.7 8.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.9 120.2 0.0 0.0 7.3 0.0 0.0 1.9 0.0 0.0 0.0 2.8 0.0 1.0 0.0 0.0 0.0 2.5 1.9 0.1 0.0 0.0 0.0 0.0 0.0 408.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 ACOT11 "BFIT, BFIT1, KIAA0707, STARD14, THEA, THEM1" ENSG00000162390 "Acyl-CoA thioesterase 11" Q8WXI4 1 54542257-54639192 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 44.4;intestine: 36.0" "Cell type enhanced" "Detected in many" "Astrocytes: 134.8;Distal enterocytes: 71.3;Late spermatids: 150.6;Proximal enterocytes: 106.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 4.6" "Lineage enriched" "Detected in single" 6 "granulocytes: 4.6" "Cell line enhanced" "Detected in many" "HaCaT: 18.9;OE19: 27.3;RT4: 40.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041047 Enhanced Supported Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 15: RT4 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA041047: AB_2677273" "unprognostic (9.73e-2)" "unprognostic (1.28e-1)" "prognostic favorable (9.37e-4)" "unprognostic (3.61e-4)" "unprognostic (5.42e-2)" "unprognostic (1.94e-1)" "unprognostic (2.20e-3)" "unprognostic (5.12e-4)" "unprognostic (1.05e-1)" "unprognostic (2.84e-2)" "unprognostic (9.60e-2)" "unprognostic (1.02e-1)" "prognostic favorable (3.07e-8)" "unprognostic (5.89e-2)" "unprognostic (1.08e-1)" "unprognostic (3.83e-2)" "unprognostic (8.49e-3)" 1.4 3.4 4.6 2.4 5.9 3.7 1.1 7.0 5.2 3.8 44.4 13.8 36.0 2.6 3.1 15.9 3.0 2.4 30.4 5.4 4.9 16.3 1.2 1.9 1.7 7.1 12.3 5.2 3.1 21.2 8.0 1.5 6.1 3.5 11.6 7.9 9.4 3.4 9.2 2.8 29.3 2.5 3.6 1.5 11.1 2.5 7.6 0.6 10.1 10.6 3.3 6.5 6.3 3.9 6.7 4.2 2.0 1.2 0.8 1.9 3.4 3.7 0.2 1.1 0.8 6.4 16.9 1.4 5.6 3.0 4.0 18.9 0.8 3.3 0.6 3.9 1.4 16.0 6.2 2.7 0.3 1.8 2.1 2.0 3.7 0.4 1.6 1.7 3.4 1.1 0.9 1.9 4.0 2.0 0.7 2.4 3.3 27.3 0.9 1.2 11.1 1.5 0.7 40.1 4.2 4.2 1.8 1.2 0.8 6.8 1.6 5.1 3.5 2.5 2.4 1.7 1.4 1.9 1.0 1.5 1.2 11.7 1.3 1.1 0.6 4.6 0.3 0.3 0.3 0.3 0.3 0.2 0.7 0.5 0.4 0.4 1.3 0.4 0.5 0.4 0.3 0.3 4.6 5.9 7.0 5.2 5.4 4.9 7.1 12.3 6.1 3.6 7.6 3.9 0.5 0.0 7.8 134.8 1.4 4.8 16.6 7.3 2.8 46.4 3.4 0.9 24.7 10.0 7.2 25.8 0.0 2.0 0.2 71.3 11.7 4.4 22.6 11.4 1.7 2.1 47.5 3.0 11.7 2.6 6.2 3.5 33.6 14.1 15.2 3.3 3.9 0.4 8.3 15.2 6.0 38.8 10.2 8.0 7.4 150.6 13.7 6.1 8.8 10.3 2.9 46.4 0.0 19.6 3.9 4.7 37.0 17.7 0.5 6.6 106.1 48.0 8.5 5.3 0.0 19.1 2.5 0.6 1.0 5.3 2.8 2.5 1.2 16.4 44.8 26.3 ACP5 "HPAP, TRAP" ENSG00000102575 "Acid phosphatase 5, tartrate resistant" P13686 19 11574660-11579008 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 174.1" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 426.9;Hofbauer cells: 426.7;Macrophages: 298.2;Proximal tubular cells: 145.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 200.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 41.1;K-562: 30.4;RPMI-8226: 41.4;SK-MEL-30: 127.6;U-138 MG: 102.9" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB002584, HPA057655, HPA059463" Enhanced Uncertain Cytosol "Intracellular and membrane" NA NA 4000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB002584: AB_564039, HPA057655: AB_2683490, HPA059463: AB_2684028" "unprognostic (4.27e-2)" "unprognostic (2.05e-2)" "unprognostic (2.93e-1)" "unprognostic (8.60e-3)" "unprognostic (2.96e-1)" "unprognostic (1.95e-2)" "unprognostic (5.21e-2)" "unprognostic (5.17e-3)" "unprognostic (5.13e-2)" "unprognostic (3.80e-1)" "unprognostic (3.66e-3)" "unprognostic (9.09e-2)" "unprognostic (1.39e-2)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "unprognostic (1.05e-1)" "unprognostic (1.19e-1)" 9.4 6.0 2.2 42.4 3.9 9.4 25.6 2.5 21.4 34.7 3.0 46.4 31.9 19.2 7.8 23.4 8.6 26.7 5.1 1.9 3.9 74.0 32.5 174.1 87.1 4.1 3.1 20.3 11.9 2.4 1.3 13.3 6.0 19.6 36.4 20.1 14.3 7.0 1.4 24.9 30.2 13.3 4.1 43.5 38.7 4.0 15.7 25.4 3.0 5.0 43.6 33.1 11.3 5.7 10.2 1.1 0.0 0.2 0.5 0.0 41.1 1.1 25.8 0.0 0.1 0.4 0.3 1.4 1.8 9.0 5.9 0.3 0.0 4.5 0.1 12.1 0.8 0.3 0.0 5.0 1.4 0.1 0.6 0.0 4.1 0.4 0.0 0.0 0.0 0.0 30.4 0.2 0.0 2.3 0.9 1.4 0.8 0.3 0.7 0.4 1.8 41.4 0.0 0.4 0.7 1.0 0.0 0.0 127.6 1.1 0.2 0.4 0.9 102.9 1.2 1.8 0.3 0.7 5.7 0.6 23.7 0.1 4.0 0.4 35.3 76.6 15.8 36.1 8.8 200.1 26.0 19.6 7.3 110.9 35.3 20.2 10.4 13.3 36.3 62.5 67.8 36.4 2.2 3.9 2.5 21.4 1.9 3.9 4.1 3.1 6.0 4.1 15.7 5.7 2.2 9.6 7.8 0.0 75.7 10.3 11.0 21.8 25.0 18.3 14.6 18.4 1.4 15.7 5.7 7.3 18.8 33.4 21.2 7.0 9.8 1.8 0.2 0.7 9.1 30.9 3.0 24.5 0.0 11.3 32.7 19.8 10.7 0.9 63.7 0.8 426.9 8.4 426.7 1.7 0.0 4.7 10.2 106.0 68.6 0.7 1.8 298.2 14.2 1.0 79.8 48.5 8.2 0.0 0.1 4.4 20.4 12.0 33.4 14.5 12.7 145.8 2.5 41.4 0.0 0.4 2.8 0.1 0.2 14.6 11.1 26.1 29.5 0.1 6.7 6.1 ACSBG2 "BGR, DKFZp434K1635, PRTD-NY3" ENSG00000130377 "Acyl-CoA synthetase bubblegum family member 2" Q5FVE4 19 6135247-6193094 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Fatty acid metabolism, Lipid metabolism, Spermatogenesis" "Developmental protein, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 89 "testis: 129.3" "Group enriched" "Detected in some" 75 "Early spermatids: 533.6;Late spermatids: 1782.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043421, HPA051013" Enhanced Supported Cytosol NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA043421: AB_10794182, HPA051013: AB_2681311" "unprognostic (4.13e-2)" "unprognostic (1.28e-1)" "unprognostic (2.47e-1)" "unprognostic (3.27e-2)" "unprognostic (4.33e-2)" "unprognostic (1.92e-4)" "unprognostic (1.96e-2)" "unprognostic (4.17e-2)" "unprognostic (2.07e-1)" "unprognostic (2.62e-1)" "unprognostic (6.88e-3)" "unprognostic (3.13e-2)" "unprognostic (3.91e-3)" "unprognostic (2.20e-1)" "unprognostic (9.23e-2)" "unprognostic (8.78e-2)" "unprognostic (4.70e-4)" 0.1 0.0 0.2 0.0 0.2 0.0 0.2 1.4 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.7 0.3 0.0 0.0 0.0 0.5 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 129.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.4 0.2 0.3 0.1 0.7 0.3 0.2 0.1 0.2 0.9 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 533.6 0.0 0.1 0.6 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.0 1782.3 11.8 0.8 0.0 1.9 0.0 0.0 0.0 1.5 3.1 0.0 0.0 7.2 0.0 0.0 0.0 1.9 0.0 0.0 6.6 0.0 0.1 15.4 9.8 0.0 0.0 1.4 0.0 0.0 0.0 0.0 ACTL8 CT57 ENSG00000117148 "Actin like 8" Q9H568 1 17755333-17827063 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 26 "testis: 7.1" "Cell type enriched" "Detected in some" 6 "Spermatogonia: 50.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "U-266/84: 245.3" "Not detected" "Not detected" HPA027176 Approved Cytosol NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Cytosol "HPA027176: AB_1844553" "unprognostic (1.79e-3)" "unprognostic (3.18e-2)" "unprognostic (4.62e-2)" "prognostic unfavorable (1.62e-6)" "unprognostic (6.18e-2)" "prognostic unfavorable (7.02e-4)" "unprognostic (1.63e-3)" "unprognostic (2.33e-2)" "unprognostic (3.18e-1)" "unprognostic (2.01e-1)" "unprognostic (3.69e-1)" "unprognostic (4.89e-1)" "unprognostic (1.43e-1)" "unprognostic (5.49e-2)" "unprognostic (4.68e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 1.4 0.0 0.1 0.2 0.0 0.2 0.1 0.0 0.2 0.0 0.2 0.0 11.0 0.3 0.2 0.6 0.0 1.5 0.0 0.0 0.1 1.4 0.0 0.5 1.4 0.0 3.3 1.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 2.5 13.3 0.0 2.4 0.0 0.0 9.2 5.9 0.1 0.0 0.0 27.5 0.0 0.0 0.4 0.0 0.0 5.2 0.5 0.0 0.5 0.4 0.0 0.0 0.1 1.9 0.2 0.1 245.3 0.1 4.9 2.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 7.8 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 1.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 50.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 ACTR2 ARP2 ENSG00000138071 "Actin related protein 2" P61160 2 65227788-65271253 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005083, HPA015050" Approved Approved Cytosol NA NA 35000000 "Cluster 14: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "CAB005083: AB_2221848, HPA015050: AB_1844556" "unprognostic (2.23e-1)" "unprognostic (1.15e-3)" "unprognostic (3.89e-2)" "unprognostic (2.52e-2)" "unprognostic (1.63e-1)" "unprognostic (2.10e-2)" "prognostic unfavorable (4.50e-4)" "unprognostic (3.88e-2)" "unprognostic (3.16e-2)" "unprognostic (7.06e-2)" "unprognostic (1.16e-2)" "unprognostic (8.59e-2)" "unprognostic (2.36e-3)" "unprognostic (3.18e-2)" "unprognostic (4.35e-2)" "unprognostic (2.15e-2)" "unprognostic (2.03e-2)" 113.0 70.7 39.9 216.2 48.3 160.5 77.0 42.2 54.7 81.4 38.3 142.4 104.8 70.1 64.5 111.0 53.7 90.9 64.9 51.4 47.2 85.6 108.9 115.9 246.4 43.6 41.4 43.9 61.7 61.9 25.0 109.6 42.9 71.7 139.1 70.2 64.9 64.1 60.4 69.4 118.2 104.4 48.0 172.0 107.3 46.2 45.5 182.2 73.1 64.9 256.3 128.6 46.0 61.1 267.3 221.2 205.5 224.5 218.8 296.1 213.2 367.3 284.1 280.0 193.6 249.3 214.2 590.6 181.8 406.9 174.3 196.8 179.8 258.3 459.4 337.2 150.8 652.1 147.6 235.9 248.0 619.8 731.6 256.5 201.6 312.2 297.7 228.6 356.6 202.0 282.1 209.2 480.0 198.2 325.4 330.6 173.2 245.7 157.5 347.9 266.0 248.6 328.7 341.7 105.2 171.6 239.0 273.5 262.0 186.9 167.6 417.4 467.9 306.5 184.8 202.8 408.9 158.0 155.2 824.1 264.4 598.7 353.9 325.4 182.4 220.6 104.3 241.4 111.8 97.1 91.1 98.6 213.1 80.4 70.3 99.2 258.2 104.1 273.3 79.3 113.9 344.5 39.9 48.3 42.2 54.7 51.4 47.2 43.6 41.4 42.9 48.0 45.5 61.1 187.1 86.6 112.7 32.3 202.4 74.7 88.0 93.0 70.0 81.8 75.8 57.1 76.3 51.5 93.2 97.5 66.7 81.8 257.9 280.5 50.9 100.5 37.5 114.5 131.4 131.0 110.8 89.8 152.6 129.0 138.6 96.0 105.0 163.2 191.1 77.8 113.6 102.9 277.7 104.3 106.0 166.5 85.5 450.1 311.8 92.5 65.3 352.0 88.9 97.4 378.9 87.9 207.0 38.7 68.9 164.4 195.3 74.4 119.7 114.9 131.1 89.0 127.7 82.4 124.9 63.3 122.8 31.4 41.8 102.5 90.6 124.4 203.2 74.2 172.8 181.7 ACVR1B "ActRIB, ACVRLK4, ALK4, SKR2" ENSG00000135503 "Activin A receptor type 1B" P36896 12 51951699-51997078 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 3.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026126, HPA063761" Approved Approved Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB026126: , HPA063761: AB_2685115" "unprognostic (8.66e-2)" "unprognostic (5.72e-2)" "unprognostic (1.16e-1)" "unprognostic (3.23e-3)" "unprognostic (2.34e-1)" "unprognostic (2.54e-1)" "unprognostic (1.21e-3)" "unprognostic (1.00e-1)" "unprognostic (7.68e-2)" "unprognostic (5.29e-2)" "unprognostic (2.56e-1)" "unprognostic (2.37e-1)" "unprognostic (4.52e-2)" "unprognostic (9.02e-2)" "unprognostic (6.60e-2)" "unprognostic (8.96e-2)" "unprognostic (4.79e-2)" 16.5 10.3 20.7 10.0 20.8 13.5 13.2 13.6 23.4 13.9 9.1 24.6 28.2 8.8 18.0 20.9 15.3 12.2 10.1 21.5 13.3 34.3 29.9 14.7 6.4 12.5 13.9 9.4 40.7 52.7 14.7 11.1 13.1 14.0 24.4 17.4 32.8 15.3 13.1 45.6 26.1 8.1 9.5 8.8 24.9 15.7 16.1 7.6 11.4 8.8 7.4 12.6 18.8 18.3 11.4 24.3 18.6 10.3 20.9 16.2 10.5 12.6 14.2 13.1 9.9 49.5 17.1 5.0 17.2 13.8 14.6 19.6 17.8 15.2 13.5 7.3 21.0 12.3 5.9 15.6 23.8 19.9 43.8 32.0 19.4 14.8 18.6 13.9 18.7 17.7 13.3 14.9 11.8 23.2 19.1 17.2 18.0 24.0 8.5 10.2 14.4 6.4 37.2 17.0 23.5 19.5 13.6 19.2 9.0 13.1 21.1 12.8 12.0 9.0 13.6 10.2 6.1 9.0 6.8 6.7 9.7 9.4 11.8 2.5 1.2 3.9 0.3 1.8 0.5 0.0 0.3 0.3 0.7 0.2 0.8 0.4 1.0 0.0 2.2 0.3 0.5 0.3 20.7 20.8 13.6 23.4 21.5 13.3 12.5 13.9 13.1 9.5 16.1 18.3 8.0 3.2 13.4 8.1 2.9 18.6 10.1 9.2 23.3 45.3 11.3 8.6 5.9 17.2 12.0 25.8 29.2 0.7 2.0 49.7 3.9 17.7 2.9 12.3 8.1 10.9 24.6 0.8 34.8 14.4 0.8 12.6 19.9 9.0 11.4 9.4 17.9 24.4 4.0 37.0 30.2 28.7 2.0 16.7 5.3 8.4 9.9 10.0 7.2 9.4 10.1 8.8 1.0 21.6 11.3 13.3 22.1 9.4 2.3 15.1 31.8 17.0 15.8 24.5 6.6 17.5 12.2 3.8 16.5 17.7 25.3 0.5 4.6 5.6 24.7 15.5 ACVR2A "ACTRII, ACVR2" ENSG00000121989 "Activin A receptor type 2A" P27037 2 147844517-147930826 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 62.5;Inhibitory neurons: 63.4;Oligodendrocyte precursor cells: 84.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 26.3;RH-30: 23.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046997 Approved Approved Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA046997: AB_10970077" "unprognostic (4.55e-2)" "unprognostic (2.26e-2)" "unprognostic (2.09e-1)" "unprognostic (7.34e-3)" "unprognostic (2.75e-1)" "unprognostic (1.17e-1)" "unprognostic (4.41e-3)" "unprognostic (8.73e-3)" "unprognostic (1.30e-2)" "unprognostic (3.61e-1)" "unprognostic (1.34e-2)" "unprognostic (1.52e-1)" "prognostic favorable (1.62e-4)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (3.95e-1)" "unprognostic (3.99e-2)" 7.3 4.0 6.2 4.6 7.4 3.3 7.0 10.8 6.4 5.4 1.0 6.3 7.7 5.2 6.6 7.2 4.5 7.7 3.7 7.5 7.5 5.6 7.4 4.6 3.1 2.6 4.5 4.5 4.4 4.3 3.9 7.7 3.9 6.8 6.5 8.3 7.5 5.2 17.5 19.5 9.3 7.0 3.8 4.0 6.8 6.4 8.6 2.3 6.7 6.3 3.9 7.4 7.4 4.6 1.8 2.1 13.2 5.0 7.3 4.7 5.4 4.1 5.0 6.9 12.0 5.8 8.1 0.1 3.6 6.7 2.5 6.2 12.0 6.1 8.8 1.4 7.3 0.9 3.6 10.2 26.3 1.0 0.9 8.1 7.3 4.5 8.9 5.2 5.3 1.6 2.0 3.5 4.7 4.8 0.4 0.8 14.9 5.5 3.6 0.2 23.3 1.3 5.6 11.5 13.0 7.3 3.5 4.2 5.4 5.6 2.5 1.4 4.1 6.4 7.5 6.1 2.9 1.0 0.3 2.4 3.9 0.5 5.2 0.2 1.7 0.2 0.6 2.0 0.2 0.1 2.4 1.1 1.3 0.3 1.5 0.3 0.0 4.8 2.0 1.7 0.2 0.7 6.2 7.4 10.8 6.4 7.5 7.5 2.6 4.5 3.9 3.8 8.6 4.6 13.7 6.4 7.0 26.8 1.5 29.7 6.9 9.5 13.1 15.4 6.8 12.4 7.9 17.2 10.7 7.3 14.6 4.9 6.0 16.5 1.9 6.3 5.3 6.4 12.2 11.9 9.0 0.0 62.5 6.3 2.5 17.4 6.6 5.7 0.0 2.2 11.7 12.1 5.4 11.8 63.4 12.9 8.2 7.3 18.9 2.1 9.9 5.7 10.6 33.7 7.2 3.3 6.2 84.9 34.1 7.6 10.0 11.3 5.2 7.7 23.7 5.8 10.2 9.4 32.9 8.3 10.9 18.2 14.1 14.4 29.8 5.3 5.9 2.9 11.7 11.8 ADAM17 "CD156B, cSVP, TACE" ENSG00000151694 "ADAM metallopeptidase domain 17" P78536 2 9488486-9556732 "CD markers, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 154.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010738, HPA051575" Approved Supported Cytosol NA NA 300000 "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" Cytosol "HPA010738: AB_1078100, HPA051575: AB_2681539" "unprognostic (2.28e-1)" "unprognostic (1.29e-3)" "unprognostic (1.28e-1)" "unprognostic (3.51e-3)" "unprognostic (1.57e-1)" "unprognostic (5.15e-2)" "unprognostic (2.12e-3)" "unprognostic (1.55e-1)" "unprognostic (4.09e-2)" "unprognostic (3.69e-1)" "unprognostic (3.53e-3)" "unprognostic (3.13e-1)" "unprognostic (3.82e-3)" "unprognostic (8.63e-2)" "unprognostic (2.61e-1)" "unprognostic (4.48e-2)" "prognostic unfavorable (4.23e-5)" 10.3 5.5 8.7 9.1 8.6 5.8 10.4 7.8 10.6 8.7 9.5 5.4 4.1 7.2 11.4 10.0 6.5 9.0 6.7 8.6 9.4 4.7 4.6 14.6 8.5 9.7 8.3 8.9 4.1 7.9 4.2 20.1 9.4 4.0 6.8 4.5 6.2 6.3 6.9 11.1 6.1 8.6 8.3 9.3 5.1 9.9 9.1 9.6 6.6 6.8 12.7 10.4 7.1 10.4 10.0 18.2 23.2 25.9 45.9 34.7 45.4 8.6 25.4 16.1 24.6 19.2 31.6 33.4 18.1 18.8 42.1 21.9 16.4 29.4 22.6 8.4 12.1 15.8 14.7 13.9 68.0 20.7 17.8 41.2 32.2 25.1 47.5 26.6 46.0 8.7 30.0 12.3 17.3 8.7 8.5 23.4 19.2 13.7 4.6 14.3 21.6 20.5 25.8 18.7 11.7 28.6 14.9 16.5 30.1 27.0 6.6 19.4 29.0 25.5 12.0 19.1 22.1 15.1 17.5 29.6 20.2 11.1 31.1 5.0 3.7 2.8 1.0 3.7 1.9 1.7 0.9 1.1 2.3 0.9 0.9 1.0 5.5 1.2 2.5 0.7 1.1 0.9 8.7 8.6 7.8 10.6 8.6 9.4 9.7 8.3 9.4 8.3 9.1 10.4 53.8 48.1 66.9 19.6 34.5 130.0 48.2 37.0 19.9 25.2 40.8 26.4 3.6 27.1 38.8 31.3 54.2 29.8 37.7 20.7 5.9 23.7 72.1 30.0 32.0 45.1 19.7 16.8 66.7 19.4 45.1 44.1 13.7 51.5 30.9 31.3 41.4 13.5 34.6 10.1 46.2 13.8 12.2 80.4 84.5 16.0 19.0 76.9 40.9 42.2 40.3 12.9 16.5 26.7 41.5 20.9 18.3 16.1 23.2 57.2 12.9 7.0 37.2 41.4 39.5 79.4 27.3 35.7 35.2 33.7 154.7 56.0 30.1 17.7 15.4 104.3 ADAMTS15 ENSG00000166106 "ADAM metallopeptidase with thrombospondin type 1 motif 15" Q8TE58 11 130448974-130476641 "Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 26.4" "Cell type enhanced" "Detected in some" "Adipocytes: 8.6;Cardiomyocytes: 11.0;Endometrial stromal cells: 15.6;Fibroblasts: 9.6;Gastric mucus-secreting cells: 8.2;Glandular and luminal cells: 7.5;Granulosa cells: 6.8;Skeletal myocytes: 6.9" "Cancer enhanced" "Detected in many" "breast cancer: 13.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 72.0;ASC TERT1: 43.0;EFO-21: 36.6;hTERT-RPE1: 19.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA042867 Uncertain Approved Cytosol "Secreted to extracellular matrix" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "HPA042867: AB_10794535" "unprognostic (7.64e-2)" "unprognostic (1.49e-3)" "unprognostic (7.15e-2)" "unprognostic (1.34e-3)" "unprognostic (1.07e-3)" "unprognostic (7.07e-3)" "unprognostic (1.01e-1)" "prognostic unfavorable (9.72e-4)" "unprognostic (6.18e-2)" "unprognostic (4.37e-2)" "unprognostic (2.56e-1)" "unprognostic (7.40e-2)" "unprognostic (1.29e-2)" "unprognostic (5.95e-3)" "unprognostic (6.68e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (5.63e-5)" 26.4 1.2 0.4 1.7 0.5 0.0 15.3 0.4 0.8 3.4 1.7 3.2 0.5 4.3 1.3 3.7 9.8 2.3 14.5 0.4 0.9 11.0 0.4 7.2 1.1 4.4 0.6 2.7 1.4 0.4 1.3 16.9 1.5 1.9 1.9 0.2 1.3 1.1 1.8 5.0 3.6 4.6 1.0 2.3 5.5 0.9 1.2 1.1 7.0 1.0 0.3 8.8 2.6 1.0 0.0 2.6 1.6 0.8 72.0 43.0 0.0 2.7 5.2 1.0 0.2 0.5 1.2 0.0 36.6 0.2 2.6 7.0 0.6 0.7 0.2 0.0 1.7 0.0 3.3 0.0 0.7 0.0 0.0 14.1 0.0 0.6 0.1 19.5 0.0 0.3 0.0 0.0 0.0 0.1 0.1 8.1 1.3 0.0 5.7 0.0 4.1 0.0 0.1 0.1 0.6 0.0 12.1 0.0 0.0 5.2 3.9 0.0 0.0 0.6 8.5 7.0 3.5 0.0 0.0 0.1 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.4 0.8 0.4 0.9 4.4 0.6 1.5 1.0 1.2 1.0 8.6 0.0 0.0 0.3 0.2 0.5 0.1 3.5 0.0 1.3 5.6 2.7 11.0 0.0 0.5 1.8 0.0 0.6 0.0 1.0 0.0 0.0 0.0 4.4 15.6 1.7 0.0 0.0 0.4 0.8 0.6 9.6 8.2 7.5 0.0 6.8 0.4 0.1 0.9 0.0 1.6 0.5 2.0 0.0 0.3 0.0 5.0 0.3 3.6 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.9 0.7 0.0 0.0 0.1 1.0 0.5 0.0 0.0 6.9 3.6 0.2 0.3 0.0 0.3 0.8 0.1 0.0 1.8 0.1 ADCY7 "AC7, KIAA0037" ENSG00000121281 "Adenylate cyclase 7" P51828 16 50246137-50318135 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 42.8;granulocytes: 50.6;Kupffer cells: 65.1;Langerhans cells: 48.0;Macrophages: 45.4;Microglial cells: 52.5;monocytes: 42.4;NK-cells: 76.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 81.0;HMC-1: 194.6;RPMI-8226: 100.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041218, HPA048241" Uncertain Approved Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA041218: AB_2677365, HPA048241: AB_2680326" "unprognostic (1.98e-1)" "prognostic unfavorable (5.31e-4)" "unprognostic (1.24e-1)" "unprognostic (1.78e-1)" "unprognostic (3.77e-1)" "unprognostic (2.80e-1)" "unprognostic (3.90e-2)" "unprognostic (7.75e-2)" "unprognostic (1.21e-1)" "unprognostic (2.56e-2)" "unprognostic (1.65e-1)" "unprognostic (1.18e-1)" "unprognostic (5.59e-3)" "unprognostic (7.34e-2)" "unprognostic (2.15e-3)" "unprognostic (2.18e-1)" "unprognostic (9.52e-4)" 8.1 3.9 6.8 23.9 7.3 24.7 5.6 7.8 8.8 3.9 6.9 8.2 4.1 3.7 2.3 14.3 7.6 12.4 5.5 6.2 10.6 1.6 3.8 23.3 27.1 14.4 11.4 19.4 2.0 1.6 2.0 14.5 12.8 2.7 8.8 0.8 4.0 2.1 2.2 13.7 8.6 7.8 10.9 29.7 7.8 1.9 12.9 19.3 2.4 3.5 24.5 7.6 4.7 19.1 16.3 18.5 0.7 2.6 1.9 24.0 1.7 9.7 4.5 8.1 7.0 23.4 28.4 4.2 25.4 41.0 0.5 50.5 22.3 10.0 8.9 50.7 6.9 81.0 18.4 5.8 20.6 10.6 194.6 12.0 8.5 5.7 8.3 4.4 2.3 17.7 30.4 7.9 10.5 9.2 5.8 34.9 3.5 8.4 31.1 5.7 7.1 100.6 5.0 1.1 4.0 9.8 5.4 2.0 4.8 4.4 0.1 38.7 17.6 0.9 25.5 2.9 3.6 0.3 0.6 8.5 9.3 32.6 3.4 9.2 7.6 2.8 6.9 10.7 5.1 2.8 2.9 5.2 12.2 3.3 2.5 3.6 4.1 9.5 18.1 6.8 4.4 5.6 6.8 7.3 7.8 8.8 6.2 10.6 14.4 11.4 12.8 10.9 12.9 19.1 1.4 19.2 35.9 2.0 15.4 3.7 0.4 0.6 1.2 1.2 1.3 2.8 1.0 0.0 7.9 0.0 6.2 11.6 42.8 3.3 0.0 1.9 1.5 6.7 6.5 1.9 0.0 12.4 6.4 0.2 1.8 9.2 3.6 13.6 50.6 4.7 1.4 0.5 35.2 0.0 3.8 0.7 0.0 65.1 48.0 1.3 0.6 45.4 5.4 52.5 42.4 0.5 76.2 3.5 0.7 4.2 10.4 1.2 15.6 0.5 0.1 0.2 1.0 0.8 6.6 28.3 2.2 0.0 1.5 7.2 4.0 4.0 26.6 16.0 2.3 1.3 ADCY9 AC9 ENSG00000162104 "Adenylate cyclase 9" O60503 16 3953387-4116442 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 45.4;skeletal muscle: 52.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 95.3;Inhibitory neurons: 72.7;Oligodendrocyte precursor cells: 42.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 40.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041328, HPA044225" Approved Approved Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA041328: AB_2677414, HPA044225: AB_2678863" "unprognostic (1.78e-1)" "unprognostic (5.54e-2)" "unprognostic (2.57e-1)" "prognostic unfavorable (2.55e-5)" "unprognostic (6.62e-2)" "unprognostic (1.30e-2)" "unprognostic (2.52e-1)" "unprognostic (3.61e-2)" "unprognostic (6.93e-2)" "unprognostic (4.76e-3)" "unprognostic (5.40e-2)" "unprognostic (1.37e-1)" "prognostic favorable (5.24e-8)" "unprognostic (1.19e-1)" "unprognostic (1.66e-1)" "unprognostic (1.44e-1)" "unprognostic (1.55e-2)" 6.9 5.6 5.1 4.4 7.6 1.5 6.1 3.2 7.5 8.2 45.4 8.2 8.2 8.0 2.4 8.4 9.2 6.9 14.9 10.7 0.0 9.4 11.9 14.0 1.9 3.0 0.6 11.2 15.8 9.1 5.1 9.9 0.9 4.4 6.8 2.9 11.9 5.8 52.9 5.9 9.6 7.9 0.1 4.4 6.4 4.0 1.3 2.1 18.8 28.6 2.6 9.7 6.1 5.2 8.5 12.9 3.8 7.0 13.3 16.0 5.6 14.5 15.1 8.0 6.3 10.6 7.2 0.0 21.8 40.1 4.8 8.0 14.9 9.1 5.4 10.4 14.3 0.3 29.4 20.3 14.2 1.1 6.4 17.1 13.6 9.3 4.9 6.6 5.4 2.7 4.7 0.0 8.3 15.3 0.1 4.4 6.9 3.6 6.9 13.3 18.0 0.4 2.9 2.3 8.7 3.8 11.3 13.2 9.6 4.2 33.5 15.0 4.9 15.8 4.3 15.6 6.4 3.2 2.1 1.7 3.4 4.4 6.3 0.8 0.3 0.2 0.4 0.3 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.2 0.0 0.3 5.1 7.6 3.2 7.5 10.7 0.0 3.0 0.6 0.9 0.1 1.3 5.2 7.0 12.8 12.8 33.3 1.0 6.4 1.1 3.9 5.2 10.6 4.2 3.7 17.3 22.8 7.1 12.9 12.5 1.8 5.8 19.5 0.0 4.5 0.8 6.1 10.5 6.3 1.2 0.4 95.3 5.3 1.8 8.1 1.5 5.7 0.0 15.3 8.2 19.9 1.5 1.7 72.7 7.6 2.0 4.7 2.0 2.2 8.4 3.3 7.2 31.9 2.6 5.5 4.1 42.3 12.5 3.5 4.3 7.5 2.5 1.1 15.0 5.6 9.5 14.9 0.0 9.4 12.5 1.1 5.0 0.9 3.8 1.0 3.4 4.8 7.2 1.3 ADGRE5 "CD97, TM7LN1" ENSG00000123146 "Adhesion G protein-coupled receptor E5" P48960 19 14380501-14408725 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 211.6" "Cell type enhanced" "Detected in many" "dendritic cells: 245.4;Kupffer cells: 111.1;Macrophages: 131.6;NK-cells: 160.6;Plasma cells: 141.5;T-cells: 184.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013707 Enhanced Approved Cytosol "Secreted to blood" NA Yes 10000000 2400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA013707: AB_1846345" "unprognostic (3.16e-1)" "unprognostic (1.80e-1)" "unprognostic (5.10e-2)" "unprognostic (2.30e-1)" "unprognostic (2.85e-2)" "unprognostic (7.24e-2)" "prognostic unfavorable (3.73e-5)" "unprognostic (7.51e-2)" "unprognostic (6.06e-3)" "unprognostic (3.14e-2)" "unprognostic (1.08e-3)" "unprognostic (2.37e-1)" "prognostic unfavorable (1.87e-6)" "unprognostic (2.08e-2)" "unprognostic (4.14e-2)" "unprognostic (2.44e-2)" "unprognostic (6.41e-2)" 45.6 21.4 4.7 79.5 7.6 211.6 21.5 7.8 6.3 60.9 4.0 52.7 43.6 143.6 7.0 15.1 48.9 33.2 30.4 4.8 6.0 28.0 19.9 80.2 58.2 9.6 7.4 14.6 31.4 6.1 7.5 32.7 8.4 17.0 29.7 0.4 22.1 10.4 29.5 14.9 51.0 75.3 6.6 145.0 40.5 3.4 9.0 32.5 21.3 13.5 32.0 42.2 29.3 12.1 118.1 81.9 0.8 77.2 33.3 54.1 12.2 79.6 127.0 56.0 61.0 23.5 115.9 13.5 78.5 103.1 79.6 27.2 21.0 38.8 25.0 73.4 23.7 26.4 113.0 10.4 41.0 57.4 117.3 23.9 1.0 57.1 19.4 18.2 5.6 22.7 35.0 101.9 61.9 26.6 3.7 76.3 2.3 92.7 100.4 7.8 33.7 61.8 18.7 10.4 1.0 2.8 45.4 64.1 57.9 1.8 16.7 52.3 14.0 19.0 31.1 79.5 133.2 0.2 0.4 1.1 67.6 100.4 72.0 371.6 158.5 772.8 187.5 281.4 123.9 28.5 94.2 129.6 102.6 18.5 65.5 91.9 623.2 179.2 352.9 48.4 70.6 242.4 4.7 7.6 7.8 6.3 4.8 6.0 9.6 7.4 8.4 6.6 9.0 12.1 10.0 35.3 93.1 1.3 88.6 0.0 8.5 0.0 2.2 0.5 7.2 6.7 3.7 12.8 17.3 0.0 0.0 4.1 245.4 25.8 0.0 18.1 0.1 16.1 26.9 13.1 4.9 25.7 1.4 22.5 46.3 20.0 49.5 13.3 77.0 1.4 23.9 2.9 50.8 0.0 1.8 25.9 0.0 111.1 0.0 1.4 6.5 131.6 0.0 6.5 55.3 2.6 160.6 2.0 11.2 21.2 30.6 4.9 141.5 12.8 17.8 0.9 27.7 1.5 26.3 34.6 23.1 0.5 5.3 3.2 0.0 7.9 184.3 3.7 29.1 17.6 ADORA2B ENSG00000170425 "Adenosine A2b receptor" P29275 17 15944917-15975746 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.7;urinary bladder: 14.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 73.5;Basal respiratory cells: 75.6;Langerhans cells: 31.9;Suprabasal keratinocytes: 64.4;Urothelial cells: 32.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 14.9;myeloid DC: 9.0" "Group enriched" "Detected in many" 97 "dendritic cells: 9.0;granulocytes: 14.9;monocytes: 5.0" "Cell line enhanced" "Detected in many" "GAMG: 160.8;HMC-1: 162.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073747 Uncertain Cytosol NA Yes "Cluster 10: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA073747: " "unprognostic (6.04e-3)" "unprognostic (1.22e-1)" "unprognostic (8.14e-2)" "unprognostic (1.32e-2)" "unprognostic (4.68e-1)" "unprognostic (7.88e-3)" "unprognostic (2.64e-4)" "unprognostic (1.44e-1)" "unprognostic (1.84e-1)" "unprognostic (1.50e-2)" "unprognostic (2.18e-3)" "unprognostic (1.38e-1)" "unprognostic (1.66e-9)" "unprognostic (2.07e-1)" "unprognostic (3.49e-1)" "unprognostic (1.50e-2)" "unprognostic (2.84e-1)" 0.5 1.1 7.5 1.7 9.4 0.8 0.7 7.0 11.7 2.4 9.0 8.6 0.2 0.7 0.5 9.1 0.9 1.1 1.6 9.1 7.3 0.3 0.1 1.9 0.3 7.7 7.7 0.0 1.3 0.0 1.4 5.0 7.1 1.3 6.6 2.8 1.4 0.1 0.1 8.5 1.3 1.3 6.4 0.2 1.2 0.3 8.3 0.4 0.1 0.5 1.3 14.2 5.2 8.2 34.1 18.3 0.6 0.7 5.8 11.1 0.7 6.4 28.4 18.3 22.6 8.8 34.6 4.4 7.8 5.7 160.8 51.9 7.9 47.8 24.2 9.7 18.0 32.7 5.8 13.0 22.3 0.0 162.6 6.5 20.1 26.0 60.4 31.3 9.3 5.1 1.6 0.1 18.2 8.9 2.2 6.6 1.9 72.0 25.5 0.1 0.4 0.0 19.1 9.1 0.8 1.2 14.3 3.4 9.0 13.4 0.1 5.1 7.7 6.5 17.1 18.3 30.3 2.8 0.0 0.0 25.8 0.0 9.2 14.9 4.2 2.8 0.0 5.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.4 0.0 2.6 0.1 0.0 1.7 7.5 9.4 7.0 11.7 9.1 7.3 7.7 7.7 7.1 6.4 8.3 8.2 0.1 3.2 4.2 18.9 0.2 73.5 21.0 75.6 27.3 0.2 1.3 1.9 0.9 1.5 20.2 0.0 0.0 10.9 0.1 10.8 0.0 6.6 0.9 0.9 0.6 1.7 2.4 3.4 0.9 0.9 3.2 4.9 2.0 1.2 0.0 0.1 2.2 0.0 4.5 0.0 1.1 1.7 2.0 1.4 31.9 0.4 0.0 6.7 7.2 3.7 1.3 7.9 0.0 1.0 1.0 1.0 7.2 0.0 0.0 15.6 0.2 0.0 8.3 0.5 0.0 0.7 2.1 0.5 1.4 23.0 64.4 6.2 0.3 0.3 5.7 32.4 ADRB2 "ADRB2R, ADRBR, B2AR, BAR" ENSG00000169252 "Adrenoceptor beta 2" P07550 5 148826611-148828623 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 196.1;Basal keratinocytes: 387.5;Basal respiratory cells: 146.6;Squamous epithelial cells: 276.0;Suprabasal keratinocytes: 245.4" "Cancer enhanced" "Detected in many" "prostate cancer: 9.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 72.4;hTERT-HME1: 74.1;PC-3: 31.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003431, HPA075322" Uncertain Uncertain Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA003431: AB_1845333, HPA075322: " "unprognostic (2.28e-2)" "unprognostic (1.50e-1)" "unprognostic (1.21e-1)" "unprognostic (1.17e-2)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" "unprognostic (9.35e-3)" "unprognostic (5.54e-2)" "unprognostic (2.34e-1)" "unprognostic (9.85e-2)" "unprognostic (3.17e-2)" "unprognostic (2.23e-1)" "prognostic favorable (3.15e-9)" "unprognostic (1.55e-2)" "unprognostic (1.46e-1)" "unprognostic (1.49e-1)" "unprognostic (7.65e-2)" 19.5 1.6 4.5 3.2 4.7 12.5 18.7 5.1 4.4 13.5 1.8 2.3 1.9 2.3 1.7 15.1 4.1 3.8 6.7 5.3 4.2 1.1 14.2 19.5 4.1 6.0 5.6 0.9 1.2 2.2 0.3 9.9 6.2 9.0 2.8 0.6 4.2 1.5 11.7 21.8 2.1 3.7 6.2 7.9 7.5 0.5 7.1 2.7 1.0 8.6 6.0 6.8 7.2 7.6 23.3 0.1 0.1 0.0 0.8 0.2 0.0 4.3 13.2 6.0 6.7 0.0 9.7 0.1 6.1 1.3 21.5 20.0 0.0 27.9 6.9 0.0 0.6 0.0 5.1 0.0 0.6 0.1 11.0 0.1 72.4 2.0 74.1 5.0 2.8 0.0 0.1 8.3 16.0 0.0 0.0 12.9 0.4 0.2 31.2 6.7 4.1 13.0 3.2 5.8 0.1 0.1 5.4 0.4 2.0 2.5 0.0 7.0 12.3 0.0 5.0 7.2 3.5 1.9 0.0 0.2 0.0 15.1 2.6 16.5 21.8 67.8 151.4 37.1 112.3 21.5 34.3 93.0 24.7 15.6 5.8 53.3 35.4 37.2 53.3 28.4 2.3 53.4 4.5 4.7 5.1 4.4 5.3 4.2 6.0 5.6 6.2 6.2 7.1 7.6 196.1 112.2 31.6 1.6 16.5 387.5 36.6 146.6 127.5 0.5 23.3 15.2 18.6 0.0 67.4 0.0 0.0 0.4 59.2 3.7 0.0 2.4 0.5 3.2 0.5 40.3 3.0 1.3 0.0 0.2 0.3 6.2 35.7 3.0 118.6 0.1 6.8 14.1 17.7 0.0 0.0 3.1 16.2 20.8 54.9 0.7 0.0 21.1 30.2 15.9 4.0 4.1 90.6 0.0 0.1 8.6 0.1 0.0 23.2 23.5 0.1 0.1 27.8 5.0 0.0 19.8 9.6 0.7 0.1 276.0 245.4 0.5 40.1 0.1 3.5 61.5 ADSL ENSG00000239900 "Adenylosuccinate lyase" P30566 22 40346461-40390463 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Purine biosynthesis" Lyase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "skeletal muscle: 345.1;tongue: 242.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000525, CAB019285" Enhanced Enhanced Cytosol NA NA 440000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "CAB019285: , HPA000525: AB_1078106" "unprognostic (2.80e-1)" "unprognostic (2.12e-1)" "prognostic favorable (2.38e-4)" "unprognostic (2.64e-1)" "unprognostic (1.02e-1)" "unprognostic (6.87e-3)" "prognostic unfavorable (5.81e-8)" "unprognostic (1.35e-1)" "unprognostic (1.25e-1)" "unprognostic (3.99e-1)" "unprognostic (6.28e-2)" "unprognostic (1.85e-1)" "unprognostic (2.99e-2)" "unprognostic (8.43e-2)" "unprognostic (2.70e-1)" "unprognostic (4.06e-1)" "unprognostic (1.44e-2)" 29.8 33.9 10.6 31.1 11.2 40.6 33.1 12.5 13.3 30.7 12.9 36.5 22.7 34.9 21.9 29.8 33.5 20.6 47.4 10.9 10.6 33.6 32.1 22.7 46.9 10.5 11.7 33.5 45.2 29.3 22.0 30.2 10.9 23.8 35.4 10.3 25.7 22.3 345.1 22.2 28.8 41.1 10.0 33.5 28.0 29.2 10.5 50.5 29.6 242.3 48.5 36.0 25.2 10.8 98.0 110.2 88.3 124.9 62.6 89.5 106.5 82.0 85.2 187.3 138.1 189.0 51.9 279.0 73.2 102.3 84.9 67.3 203.5 137.4 187.7 75.3 197.5 126.5 98.4 166.5 134.6 423.0 96.3 97.7 76.5 161.5 169.8 91.3 138.9 127.3 153.1 114.3 136.4 105.0 130.2 131.2 152.5 121.3 119.3 195.1 203.6 198.2 118.9 67.8 58.8 54.4 106.2 54.1 170.7 78.5 76.8 134.7 91.2 93.3 173.7 85.3 168.8 109.0 212.6 218.2 80.9 149.5 97.7 29.0 47.2 19.9 35.5 55.2 49.5 34.6 76.1 48.5 68.1 33.5 58.3 45.0 4.1 48.2 49.7 34.4 81.7 62.3 10.6 11.2 12.5 13.3 10.9 10.6 10.5 11.7 10.9 10.0 10.5 10.8 10.0 12.8 10.8 9.4 28.3 18.1 18.8 48.6 23.9 16.1 14.8 15.0 30.0 30.0 20.8 3.7 37.5 85.3 15.5 13.0 7.9 61.3 44.0 5.6 9.2 21.6 13.8 54.6 11.4 43.7 78.9 21.2 21.4 5.6 36.8 8.8 28.9 25.6 60.3 6.7 10.7 24.1 24.4 44.8 26.7 25.2 24.8 22.7 12.4 1.0 41.9 45.1 19.6 9.5 9.8 33.7 15.6 14.3 52.4 21.3 21.4 19.7 12.3 18.1 26.3 38.5 20.8 61.2 82.8 35.7 15.2 33.1 32.2 8.7 37.7 14.1 AGBL3 "CCP3, MGC32955" ENSG00000146856 "ATP/GTP binding protein like 3" Q8NEM8 7 134986508-135147963 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "epididymis: 7.9" "Cell type enhanced" "Detected in many" "Early spermatids: 70.5;Excitatory neurons: 40.7;Inhibitory neurons: 34.2;Oligodendrocytes: 37.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HEK 293: 5.5" "Low region specificity" "Detected in all" "HPA020397, HPA024150" Uncertain Approved Cytosol NA No "Cluster 22: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol "HPA020397: AB_2242453, HPA024150: AB_1844639" "unprognostic (8.84e-2)" "unprognostic (1.49e-2)" "unprognostic (4.72e-2)" "unprognostic (2.18e-1)" "unprognostic (1.47e-1)" "unprognostic (3.39e-3)" "unprognostic (3.32e-3)" "unprognostic (4.18e-2)" "unprognostic (7.15e-4)" "unprognostic (5.00e-3)" "unprognostic (6.10e-4)" "unprognostic (3.16e-2)" "prognostic unfavorable (4.02e-4)" "unprognostic (2.18e-2)" "unprognostic (2.14e-1)" "unprognostic (8.13e-2)" "unprognostic (1.11e-3)" 1.0 0.9 1.0 2.3 1.3 2.2 2.3 2.0 3.0 0.8 1.2 1.2 0.8 2.9 7.9 0.1 1.8 0.7 0.8 1.0 1.9 1.7 0.6 1.8 2.3 1.3 1.2 3.5 2.3 0.4 0.3 0.9 1.1 1.9 1.5 1.3 2.5 2.1 2.4 2.5 2.0 1.6 1.3 3.8 2.5 5.1 1.7 0.9 2.8 0.8 0.9 0.3 0.2 1.8 1.7 0.9 2.2 0.5 0.6 0.8 1.3 0.4 0.0 0.3 0.5 3.0 1.9 2.7 0.8 0.0 0.9 1.8 0.8 0.3 0.0 2.2 5.5 2.3 4.0 3.0 0.0 1.0 0.0 0.1 0.0 1.3 0.0 0.0 0.9 3.0 1.7 1.5 0.3 1.5 0.6 0.9 1.9 0.2 0.2 1.6 0.1 0.8 1.5 0.3 1.3 1.4 0.3 0.0 0.2 0.0 1.2 2.3 0.0 0.2 0.5 0.3 1.0 3.3 1.1 1.3 1.1 2.8 2.7 0.0 0.1 0.1 0.8 0.0 0.7 0.8 0.4 0.9 0.2 0.7 0.7 1.7 0.2 0.9 0.0 0.6 0.6 0.6 1.0 1.3 2.0 3.0 1.0 1.9 1.3 1.2 1.1 1.3 1.7 1.8 6.7 3.2 0.6 18.3 3.5 1.3 0.9 1.2 2.8 5.1 2.2 2.2 2.1 4.3 2.0 9.2 2.1 0.3 0.9 0.6 7.9 4.6 70.5 6.6 1.8 4.8 3.0 3.0 40.7 2.9 0.4 2.8 4.6 2.6 1.3 3.2 5.0 1.9 0.5 3.3 34.2 0.4 0.0 1.3 0.7 11.8 3.4 0.8 5.4 22.5 6.9 2.8 1.0 16.6 37.3 1.7 0.1 2.2 6.1 1.3 0.4 7.6 6.4 3.3 0.0 2.0 4.1 21.4 6.3 1.2 0.3 0.1 2.0 2.4 0.5 1.0 AHCY SAHH ENSG00000101444 Adenosylhomocysteinase P23526 20 34280268-34311802 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "One-carbon metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 275.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041225, HPA044675" Approved Supported Cytosol NA NA 5000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA041225: AB_2677371, HPA044675: AB_2679041" "unprognostic (3.35e-1)" "unprognostic (2.17e-1)" "unprognostic (2.41e-2)" "unprognostic (1.32e-2)" "unprognostic (7.74e-2)" "unprognostic (3.15e-2)" "unprognostic (7.34e-3)" "unprognostic (1.10e-1)" "unprognostic (8.88e-2)" "unprognostic (2.61e-1)" "unprognostic (4.21e-2)" "unprognostic (1.24e-1)" "unprognostic (5.27e-2)" "unprognostic (2.06e-1)" "unprognostic (1.20e-1)" "unprognostic (1.88e-1)" "unprognostic (2.93e-3)" 44.9 56.7 38.5 34.3 41.1 59.3 71.0 41.7 40.1 69.2 45.2 61.8 72.7 55.8 65.7 140.9 75.8 31.1 67.1 38.8 42.8 155.5 187.4 41.5 45.4 42.1 42.2 116.4 161.5 65.5 45.4 39.5 43.3 83.9 58.0 24.6 57.7 49.6 109.3 50.9 54.8 43.6 42.5 39.9 75.8 82.0 42.5 51.7 95.1 63.6 55.9 59.3 66.9 44.6 270.8 345.9 143.6 254.7 163.6 174.8 164.4 108.1 153.9 235.5 186.1 942.0 226.2 417.0 188.0 139.4 152.0 301.2 340.7 606.4 150.3 55.6 207.6 503.9 157.3 612.7 175.5 238.1 158.3 364.1 271.2 146.9 233.8 125.9 162.9 152.0 250.1 102.7 126.8 285.2 313.3 224.2 185.0 343.0 332.7 231.8 364.6 294.1 212.7 188.3 247.8 164.8 216.1 252.6 364.5 112.8 380.3 217.9 104.5 203.3 215.5 104.1 207.6 151.7 239.0 252.3 150.2 144.4 111.3 9.0 32.9 1.0 8.9 60.7 15.0 20.5 13.0 11.5 48.8 19.4 13.8 16.1 2.7 11.6 40.8 55.1 16.4 28.2 38.5 41.1 41.7 40.1 38.8 42.8 42.1 42.2 43.3 42.5 42.5 44.6 13.2 41.7 23.2 5.5 35.3 36.7 88.2 106.1 68.9 11.7 77.6 82.0 47.8 44.3 43.2 27.6 0.0 109.0 31.4 36.6 58.7 73.5 76.5 30.9 110.6 27.1 21.0 60.8 9.0 82.4 165.3 35.6 83.6 42.8 21.0 42.8 19.6 70.4 115.7 11.8 8.4 73.5 30.5 52.2 32.4 187.4 42.6 34.5 26.6 2.8 26.4 42.4 5.2 5.0 16.4 60.4 41.2 40.6 66.2 95.8 51.4 275.0 17.9 15.2 13.1 27.8 34.6 43.5 45.3 100.8 39.5 91.9 19.8 84.3 117.1 82.6 AHCYL1 "IRBIT, PPP1R78, XPVKONA" ENSG00000168710 "Adenosylhomocysteinase like 1" O43865 1 109984765-110023742 "Metabolic proteins, Predicted intracellular proteins, Transporters" "One-carbon metabolism" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 337.1" "Cell type enhanced" "Detected in all" "Astrocytes: 328.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042589 Approved Supported Cytosol NA NA 160000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" Cytosol "HPA042589: AB_10793885" "unprognostic (8.72e-2)" "unprognostic (2.34e-1)" "prognostic favorable (7.00e-4)" "unprognostic (1.83e-3)" "unprognostic (5.01e-2)" "unprognostic (1.81e-1)" "unprognostic (2.72e-2)" "unprognostic (3.09e-2)" "unprognostic (1.32e-1)" "unprognostic (7.01e-2)" "unprognostic (2.46e-1)" "unprognostic (1.68e-1)" "unprognostic (2.38e-2)" "unprognostic (3.79e-2)" "unprognostic (2.89e-1)" "unprognostic (8.87e-2)" "unprognostic (4.84e-3)" 68.0 66.1 222.3 33.5 271.0 14.7 51.4 244.2 238.0 66.5 175.2 52.1 126.8 54.3 91.8 47.9 72.9 65.2 38.2 183.8 300.2 102.1 69.2 44.6 31.5 337.1 292.5 53.0 73.3 178.5 51.4 56.3 271.6 44.2 51.6 68.8 50.9 64.1 91.8 38.5 64.1 57.3 310.0 34.6 56.3 28.3 299.6 32.2 75.3 44.6 37.5 49.3 39.9 295.6 100.9 83.4 77.3 80.5 182.8 106.8 127.2 78.1 87.7 72.2 70.7 65.3 56.4 42.5 64.9 115.5 55.0 63.0 69.2 89.1 95.0 355.3 59.8 70.8 106.5 69.5 188.4 61.1 47.7 109.7 55.2 90.0 131.0 175.5 92.2 70.7 51.8 84.1 75.7 80.1 51.3 30.2 91.5 140.6 64.1 54.9 161.1 47.7 157.7 99.8 75.4 49.1 121.1 142.9 165.2 116.8 76.5 60.3 80.3 69.3 67.3 82.8 70.4 68.8 30.5 36.0 142.2 65.7 145.1 3.9 5.0 4.6 2.2 5.4 2.3 3.9 2.3 3.1 3.5 4.4 2.4 2.3 4.7 2.5 3.8 3.2 5.0 2.2 222.3 271.0 244.2 238.0 183.8 300.2 337.1 292.5 271.6 310.0 299.6 295.6 67.3 35.3 74.8 328.1 30.1 89.2 100.1 61.7 47.8 62.3 105.9 71.2 49.8 85.8 68.0 117.7 223.1 80.7 29.4 72.0 125.2 142.2 41.6 226.2 69.1 59.0 85.5 42.0 48.7 110.5 50.4 107.4 69.8 181.1 31.7 81.1 61.8 158.2 42.8 63.9 50.4 71.1 65.1 75.8 67.7 29.6 93.5 62.2 62.2 53.4 57.2 99.9 19.6 60.8 53.2 100.8 38.5 81.6 27.0 108.1 134.3 143.6 83.5 105.7 46.0 87.9 105.7 31.6 13.1 75.6 108.4 100.3 26.8 61.4 78.9 134.2 AHSA1 "Aha1, C14orf3, hAha1, p38" ENSG00000100591 "Activator of HSP90 ATPase activity 1" O95433 14 77457870-77469472 "Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Stress response" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 345.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000903, CAB006244" Supported Supported Cytosol NA NA 120000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB006244: AB_425858, HPA000903: AB_1078112" "unprognostic (3.91e-1)" "unprognostic (1.92e-1)" "unprognostic (1.06e-1)" "unprognostic (2.69e-1)" "unprognostic (3.48e-1)" "unprognostic (1.49e-3)" "prognostic unfavorable (5.04e-6)" "unprognostic (3.63e-2)" "unprognostic (1.54e-1)" "unprognostic (1.06e-1)" "unprognostic (2.88e-1)" "unprognostic (2.63e-2)" "unprognostic (2.16e-2)" "unprognostic (1.33e-1)" "unprognostic (3.06e-2)" "unprognostic (1.44e-2)" "unprognostic (3.01e-1)" 70.9 99.1 134.7 51.8 136.1 51.0 55.4 142.0 345.7 63.9 135.3 82.4 44.8 80.1 72.3 72.6 120.9 39.4 116.7 134.9 139.1 73.2 71.8 60.8 71.6 141.8 139.3 69.8 50.3 65.5 66.7 76.5 144.0 64.4 71.8 39.1 56.7 70.3 140.2 59.8 54.9 85.0 139.4 55.7 61.9 99.4 142.5 65.2 47.1 118.3 91.4 76.9 61.1 156.2 185.0 356.7 103.1 131.9 159.1 110.3 175.1 131.2 111.6 223.0 165.3 277.0 163.4 361.3 103.0 145.1 258.4 204.7 386.2 186.5 231.8 131.8 207.5 156.1 181.6 343.3 113.7 102.6 230.8 98.3 244.9 150.7 72.2 133.1 209.9 225.3 205.5 115.6 138.5 522.6 278.6 207.8 170.6 347.7 372.9 210.2 110.3 178.1 178.2 187.1 155.0 161.4 119.2 302.9 115.8 154.4 174.4 152.6 100.3 115.3 162.1 126.2 198.7 103.7 241.6 273.8 169.1 211.3 131.1 82.7 51.5 67.9 66.4 74.0 76.9 81.0 59.8 68.0 67.2 63.7 69.0 70.6 39.8 88.7 92.5 66.4 77.2 52.2 134.7 136.1 142.0 345.7 134.9 139.1 141.8 139.3 144.0 139.4 142.5 156.2 46.6 35.3 21.6 10.1 59.4 156.0 208.2 82.8 74.0 36.0 49.9 46.6 92.2 42.9 57.0 27.6 85.5 153.4 66.8 60.0 74.3 74.2 40.6 112.6 60.8 54.9 78.3 55.8 14.6 48.8 113.3 68.3 25.5 59.6 76.2 55.2 28.9 41.0 93.5 18.5 14.7 70.5 65.1 26.7 117.5 34.2 67.7 52.6 90.7 12.2 58.5 46.6 61.8 10.1 23.6 67.8 65.6 66.5 54.1 145.4 56.4 87.0 132.2 54.1 98.6 46.9 135.0 92.0 57.3 67.7 140.1 136.7 92.3 86.0 85.2 120.1 AIF1 "AIF-1, Em:AF129756.17, IBA1, IRT-1" ENSG00000204472 "Allograft inflammatory factor 1" P55008 6 31615217-31617021 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 235.0;lymphoid tissue: 346.6" "Group enriched" "Detected in many" 22 "Hofbauer cells: 1777.1;Kupffer cells: 2140.2;Langerhans cells: 1359.1;Macrophages: 1494.0;monocytes: 1022.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 26 "classical monocyte: 3823.3;intermediate monocyte: 6550.1;myeloid DC: 2043.3;neutrophil: 2943.0;non-classical monocyte: 7744.5" "Group enriched" "Detected in all" 74 "dendritic cells: 2043.3;granulocytes: 2943.0;monocytes: 7744.5" "Group enriched" "Detected in some" 4 "HEL: 204.6;HMC-1: 329.6;NB-4: 264.7;THP-1: 184.2;U-937: 114.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049234, HPA062949" Enhanced Uncertain Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "HPA049234: AB_2680685, HPA062949: AB_2732694" "unprognostic (3.20e-2)" "unprognostic (7.21e-3)" "unprognostic (6.11e-2)" "unprognostic (2.33e-2)" "unprognostic (2.46e-1)" "unprognostic (1.13e-1)" "unprognostic (6.98e-2)" "unprognostic (4.83e-2)" "unprognostic (2.72e-2)" "unprognostic (7.56e-2)" "unprognostic (1.41e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (2.30e-5)" "unprognostic (1.29e-1)" "unprognostic (1.02e-2)" "unprognostic (9.59e-2)" "unprognostic (4.89e-2)" 79.6 46.6 24.9 182.3 25.5 235.0 47.2 26.6 33.0 29.3 32.2 48.3 36.4 17.1 12.1 18.7 19.7 61.3 21.1 25.0 31.3 74.3 81.2 99.3 116.8 45.1 36.4 14.4 12.4 12.9 17.3 109.5 36.8 22.3 57.2 3.9 20.3 24.0 6.1 11.7 44.5 74.7 34.3 346.6 22.2 8.7 32.1 69.1 13.8 16.6 57.1 95.3 13.5 42.7 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 204.6 0.0 0.0 0.0 30.0 329.6 0.0 0.0 0.0 0.0 0.0 0.0 51.6 0.9 0.2 0.0 0.0 2.3 264.7 0.4 0.0 0.0 35.9 0.4 8.9 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 184.2 0.1 0.0 0.2 0.1 0.3 0.2 0.0 1.3 0.2 114.6 0.0 33.1 3823.3 177.9 10.2 6550.1 12.7 57.5 10.8 9.3 2043.3 6.3 33.1 26.2 2943.0 14.5 7744.5 144.2 10.7 4449.8 24.9 25.5 26.6 33.0 25.0 31.3 45.1 36.4 36.8 34.3 32.1 42.7 12.0 25.6 59.6 0.0 39.2 32.5 0.7 0.0 0.6 0.1 5.3 24.3 7.5 18.6 19.2 42.3 0.0 11.1 31.2 1.0 0.0 0.3 1.9 0.6 0.7 28.7 1.2 65.0 0.0 0.4 15.4 20.6 0.5 0.4 68.3 0.4 35.3 13.4 1777.1 0.0 0.0 0.1 0.0 2140.2 1359.1 4.9 7.5 1494.0 39.2 10.3 1022.6 0.0 32.0 0.5 0.1 0.2 11.1 0.7 7.2 0.4 0.3 4.2 10.2 0.1 52.6 4.7 6.5 0.5 1.5 2.1 28.3 22.7 46.1 1.9 0.6 0.3 AIMP1 "EMAP-2, EMAPII, p43, SCYE1" ENSG00000164022 "Aminoacyl tRNA synthetase complex interacting multifunctional protein 1" Q12904 4 106315544-106349456 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis, Inflammatory response, Protein biosynthesis" "Cytokine, RNA-binding, tRNA-binding" Leukodystrophy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017618, HPA018476" Supported Enhanced Cytosol "Secreted to blood" NA NA 6500000 35000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB017618: AB_2285445, HPA018476: AB_1848137" "unprognostic (1.17e-3)" "unprognostic (1.41e-1)" "unprognostic (1.11e-1)" "unprognostic (2.36e-1)" "unprognostic (1.22e-1)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.29e-3)" "unprognostic (8.10e-2)" "unprognostic (4.85e-2)" "unprognostic (8.90e-2)" "unprognostic (5.86e-2)" "unprognostic (1.23e-2)" "unprognostic (1.71e-2)" "unprognostic (2.33e-1)" "unprognostic (7.13e-2)" "unprognostic (1.73e-1)" "unprognostic (2.27e-2)" 32.5 33.4 23.3 31.4 25.9 60.1 44.4 25.8 32.9 32.2 25.2 42.1 39.9 34.5 35.1 37.7 32.1 32.1 34.4 23.2 25.0 40.3 35.8 29.0 38.6 25.8 25.7 42.3 32.4 37.8 25.6 30.1 25.7 33.1 41.6 36.0 35.0 35.1 65.3 29.4 37.8 32.3 24.3 33.5 34.8 23.5 24.8 35.4 38.9 50.4 39.2 40.9 30.7 27.8 66.7 46.1 47.3 60.3 51.0 78.0 68.1 80.8 69.7 73.9 87.7 81.9 97.8 109.4 61.6 79.6 50.5 61.4 69.6 86.6 98.8 62.1 47.4 64.2 63.8 134.0 101.3 147.4 75.4 62.9 100.2 74.5 117.5 56.3 64.3 68.2 120.8 58.0 82.4 58.5 99.2 78.2 51.4 94.6 46.5 81.1 86.3 101.5 94.7 60.5 72.9 56.9 52.7 158.1 86.4 61.7 75.2 107.8 50.5 87.9 73.1 66.1 105.9 71.5 98.9 110.0 74.6 112.7 97.0 60.6 54.7 55.0 42.9 61.8 51.7 57.4 54.0 43.9 58.5 55.8 55.8 51.0 7.7 51.9 73.4 74.7 72.2 34.9 23.3 25.9 25.8 32.9 23.2 25.0 25.8 25.7 25.7 24.3 24.8 27.8 87.4 70.5 55.2 18.6 72.7 50.2 147.0 166.1 50.7 49.7 71.3 87.8 95.4 82.9 130.2 66.2 35.5 124.5 58.1 83.3 156.5 121.1 79.0 75.4 83.8 60.8 73.8 66.7 17.3 126.6 144.8 66.0 48.9 130.8 79.3 64.2 61.4 109.8 109.6 25.2 20.4 144.4 116.0 90.1 53.3 19.4 99.1 68.8 32.0 16.9 117.2 56.0 74.2 24.6 38.3 118.3 93.7 85.4 40.9 141.8 146.8 166.1 105.6 45.5 59.2 77.5 128.4 127.2 74.3 66.4 50.2 150.9 68.9 74.3 142.2 173.1 AIMP2 "JTV-1, JTV1, p38, PRO0992" ENSG00000106305 "Aminoacyl tRNA synthetase complex interacting multifunctional protein 2" Q13155 7 6009255-6023834 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Differentiation, Protein biosynthesis" "Developmental protein" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 154.9;tongue: 102.5" "Cell type enhanced" "Detected in all" "Early spermatids: 134.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019098, HPA020057" Supported Approved Cytosol NA Yes 35000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA019098: AB_1852040, HPA020057: AB_1852042" "unprognostic (1.24e-3)" "unprognostic (1.66e-2)" "unprognostic (7.30e-2)" "unprognostic (2.77e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (3.69e-4)" "unprognostic (9.29e-2)" "unprognostic (3.41e-2)" "unprognostic (8.75e-2)" "unprognostic (1.11e-1)" "unprognostic (5.13e-2)" "unprognostic (3.96e-1)" "prognostic favorable (1.38e-5)" "unprognostic (7.44e-2)" "unprognostic (8.97e-2)" "unprognostic (1.26e-2)" "prognostic unfavorable (3.09e-4)" 19.2 21.0 13.6 14.3 15.1 12.4 17.3 15.6 17.0 11.0 12.8 25.8 47.7 16.7 16.7 22.0 14.4 8.8 45.3 15.4 14.6 25.7 33.8 12.6 14.3 14.9 14.5 7.4 17.0 28.7 7.8 13.4 14.7 11.9 24.4 11.9 16.4 15.2 154.9 21.6 27.8 19.3 15.2 13.0 14.6 44.1 15.1 15.4 25.8 102.5 19.5 17.0 13.7 16.2 90.3 100.2 33.1 48.3 34.5 37.3 113.7 49.5 33.3 79.9 59.4 110.1 58.5 109.6 46.2 51.4 90.1 98.6 113.6 74.2 49.6 35.6 84.0 61.2 54.8 84.2 106.2 86.7 53.1 57.4 109.1 72.3 117.9 13.3 60.2 43.8 86.7 35.6 59.4 142.6 37.4 157.2 136.0 44.3 70.4 83.5 73.8 93.3 119.1 41.7 66.1 62.6 50.4 101.3 72.9 41.9 94.5 70.1 51.8 46.0 112.9 77.0 111.2 44.5 73.9 95.5 38.5 122.3 75.6 46.7 61.4 19.5 41.5 77.5 34.9 47.3 27.7 32.5 92.4 31.9 27.1 28.9 6.0 48.3 57.9 58.7 32.3 43.4 13.6 15.1 15.6 17.0 15.4 14.6 14.9 14.5 14.7 15.2 15.1 16.2 15.0 9.6 10.3 8.1 13.0 10.8 22.5 58.5 24.5 10.2 11.8 15.1 2.2 28.6 40.2 12.9 6.2 50.8 10.1 17.6 70.5 52.6 134.7 25.3 23.9 20.0 6.7 24.2 5.8 57.3 64.0 15.1 23.4 20.6 12.6 16.7 13.2 38.8 50.0 6.7 6.7 18.2 57.0 19.1 14.3 84.5 19.9 18.1 19.6 1.9 40.3 17.8 17.5 5.0 10.4 40.1 14.5 18.0 23.8 23.0 59.3 67.7 34.9 11.2 13.1 16.0 24.5 91.1 26.8 37.1 11.6 39.5 12.6 38.0 39.8 17.8 AIP "ARA9, FKBP16, FKBP37, XAP2" ENSG00000110711 "Aryl hydrocarbon receptor interacting protein" O00170 11 67483026-67491103 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cushing syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033674, HPA050217, CAB069477" Approved Supported Cytosol NA NA 13000 "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "CAB033674: AB_2224981, CAB069477: AB_10002466, HPA050217: AB_2681055" "unprognostic (2.59e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (1.93e-4)" "unprognostic (8.15e-2)" "unprognostic (9.54e-2)" "unprognostic (4.02e-2)" "unprognostic (2.17e-2)" "unprognostic (1.14e-1)" "unprognostic (6.19e-3)" "unprognostic (2.18e-1)" "unprognostic (9.75e-2)" "unprognostic (1.16e-1)" "unprognostic (5.28e-2)" "unprognostic (3.10e-1)" "unprognostic (2.70e-1)" "unprognostic (2.40e-2)" "unprognostic (9.45e-2)" 62.9 58.1 72.5 47.4 77.6 40.4 58.5 74.7 82.4 84.5 66.7 78.4 33.7 71.0 32.4 38.9 66.9 39.4 72.1 70.3 74.3 68.0 51.6 62.3 89.5 75.9 72.7 77.9 48.8 35.4 51.1 33.5 74.6 60.8 20.1 22.9 40.6 36.0 46.4 39.5 64.7 28.8 71.8 85.1 57.0 29.7 73.1 78.7 63.6 45.8 49.1 73.1 62.6 80.4 80.8 91.1 51.6 49.9 64.8 64.2 39.3 49.7 61.2 83.6 60.9 143.7 77.9 142.2 118.1 55.3 63.5 63.9 59.2 51.9 32.1 209.3 63.5 86.5 98.7 87.0 67.1 87.5 145.1 77.8 48.3 74.6 48.4 81.4 43.0 138.6 50.0 83.6 55.5 153.7 187.7 214.6 49.0 122.0 115.7 82.2 78.5 126.5 59.5 47.2 81.4 81.3 64.4 45.5 204.3 19.9 60.9 87.2 71.5 73.4 71.1 108.9 46.3 67.4 99.8 112.7 100.4 67.4 57.7 192.5 117.9 135.6 194.3 144.6 212.0 241.6 227.4 227.6 179.8 221.5 203.4 194.7 78.2 165.3 175.0 207.9 352.4 182.4 72.5 77.6 74.7 82.4 70.3 74.3 75.9 72.7 74.6 71.8 73.1 80.4 57.2 32.1 25.6 6.8 69.4 30.3 35.8 54.2 31.9 36.8 24.6 33.1 23.1 30.0 33.7 49.7 4.2 56.4 61.9 50.1 82.2 46.8 25.3 12.7 31.0 54.0 31.8 22.5 4.0 42.2 63.5 51.0 23.4 18.0 77.3 51.7 45.7 23.3 66.7 37.0 4.9 34.7 48.8 65.0 54.6 14.2 53.1 56.1 56.9 5.6 72.5 49.6 76.2 5.0 10.5 41.2 53.5 35.3 50.2 42.7 86.1 98.3 17.4 29.4 39.5 36.4 86.5 21.7 28.4 19.4 21.2 59.5 90.6 42.0 25.4 52.2 AK1 ENSG00000106992 "Adenylate kinase 1" P00568 9 127866486-127877675 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1346.2;tongue: 783.3" "Cell type enhanced" "Detected in all" "Early spermatids: 281.3;Late spermatids: 1031.8;Muller glia cells: 287.6;Peritubular cells: 386.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-2197: 163.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006456, CAB009893" Enhanced Supported Cytosol NA NA 24000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "CAB009893: AB_2225151, HPA006456: AB_1078116" "unprognostic (6.07e-3)" "unprognostic (1.44e-2)" "unprognostic (2.36e-2)" "unprognostic (1.03e-1)" "unprognostic (3.44e-1)" "unprognostic (3.09e-1)" "unprognostic (1.52e-2)" "unprognostic (3.12e-2)" "unprognostic (2.19e-1)" "unprognostic (5.74e-2)" "unprognostic (6.65e-3)" "unprognostic (2.07e-1)" "unprognostic (1.81e-2)" "prognostic favorable (7.31e-4)" "unprognostic (2.62e-1)" "unprognostic (8.40e-3)" "unprognostic (6.99e-3)" 28.5 34.5 81.3 11.5 79.2 28.4 17.0 87.9 95.1 37.5 145.8 33.8 17.9 14.3 28.5 32.0 342.2 22.5 270.0 79.5 88.5 31.4 26.5 74.6 5.0 97.4 99.8 45.0 14.9 47.0 33.8 7.6 99.0 17.1 39.5 29.0 33.1 35.9 1346.2 14.2 12.1 21.9 105.0 20.8 23.9 63.1 89.4 3.9 34.8 783.3 12.6 19.7 19.4 97.2 56.7 23.6 30.1 40.4 71.2 142.9 27.4 38.3 38.2 66.7 40.4 18.0 34.9 1.5 40.8 79.4 44.1 79.2 0.3 43.1 26.6 9.0 26.1 8.3 65.2 31.6 40.1 0.0 1.0 110.9 81.8 49.9 35.5 36.8 90.3 0.8 33.7 2.3 76.7 53.5 0.1 1.1 10.6 139.7 74.2 1.3 30.0 12.6 44.8 4.1 48.3 30.4 101.0 57.4 29.8 15.3 45.8 33.3 75.9 45.9 18.8 163.8 37.3 3.5 0.6 0.2 57.7 0.3 32.4 0.2 0.0 0.1 0.3 0.0 0.2 0.0 0.1 0.2 0.0 0.2 0.0 0.2 0.5 0.2 0.1 0.9 0.0 0.3 81.3 79.2 87.9 95.1 79.5 88.5 97.4 99.8 99.0 105.0 89.4 97.2 12.8 41.7 148.1 25.8 2.6 26.4 17.2 84.5 6.2 54.6 11.5 7.9 49.7 28.6 79.4 7.3 16.7 7.5 5.7 210.1 17.6 116.7 281.3 7.3 8.0 39.8 106.3 97.0 11.1 60.9 46.8 37.3 46.4 4.8 1.3 2.7 49.2 77.3 59.3 48.8 12.0 62.7 120.1 3.7 22.3 1031.8 226.5 7.9 83.6 2.8 2.3 287.6 10.3 4.5 9.7 57.2 132.7 386.3 4.2 14.4 22.8 8.2 186.5 69.5 26.3 107.2 56.4 20.2 16.7 33.6 28.4 13.5 7.1 83.4 65.5 25.3 AKAP13 "AKAP-Lbc, ARHGEF13, BRX, c-lbc, HA-3, Ht31, LBC, PROTO-LB" ENSG00000170776 "A-kinase anchoring protein 13" Q12802 15 85380571-85749358 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 161.8" "Low region specificity" "Detected in all" HPA019773 Approved Supported Cytosol NA NA 14000 "Cluster 2: Granulocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "HPA019773: AB_1844686" "unprognostic (4.61e-2)" "unprognostic (1.16e-1)" "unprognostic (3.96e-2)" "unprognostic (2.78e-2)" "unprognostic (1.04e-1)" "unprognostic (1.58e-1)" "unprognostic (5.33e-2)" "unprognostic (7.72e-2)" "unprognostic (1.33e-1)" "unprognostic (1.11e-1)" "unprognostic (3.99e-2)" "unprognostic (3.92e-1)" "unprognostic (6.69e-2)" "unprognostic (4.88e-2)" "unprognostic (4.80e-2)" "unprognostic (1.46e-1)" "unprognostic (3.81e-3)" 37.7 18.9 10.0 38.7 9.2 56.1 32.1 1.7 9.3 28.5 66.1 25.9 16.7 83.0 20.7 25.6 22.7 44.6 66.6 11.0 17.7 14.4 22.2 54.1 47.6 16.7 17.6 26.7 54.5 11.8 18.5 26.0 13.9 20.3 21.3 8.3 23.9 23.5 83.9 24.7 32.5 40.3 9.7 38.3 34.4 20.0 15.0 46.3 32.7 60.3 46.5 32.9 26.7 16.3 13.2 29.0 20.8 7.8 31.3 34.6 11.2 10.6 23.5 9.4 9.0 11.3 11.0 62.0 14.6 19.2 23.8 26.5 23.9 9.9 9.0 45.2 11.0 83.8 20.0 8.6 17.3 17.2 161.8 25.6 25.5 11.6 39.8 10.6 25.2 22.4 5.5 29.6 14.7 6.3 24.7 12.8 13.5 22.8 11.5 16.7 20.6 23.5 15.3 27.0 13.1 23.4 27.9 8.3 14.5 22.7 6.0 14.3 30.2 11.4 7.8 6.7 10.7 46.1 30.1 48.9 6.8 55.2 9.0 282.9 66.0 181.4 122.2 54.9 68.3 74.9 81.6 93.3 38.8 68.8 68.2 75.5 104.3 108.2 77.5 100.6 73.2 48.0 10.0 9.2 1.7 9.3 11.0 17.7 16.7 17.6 13.9 9.7 15.0 16.3 110.5 125.0 431.2 88.2 186.8 75.7 105.2 29.1 57.5 18.6 50.2 39.9 215.2 91.5 71.6 40.5 41.7 36.7 336.8 143.3 5.9 83.4 258.9 155.6 327.0 121.5 63.5 37.0 51.2 69.6 27.6 119.6 170.2 323.6 279.5 65.6 75.7 53.7 79.2 13.5 13.0 57.8 36.7 147.1 276.3 166.3 77.6 257.9 99.6 290.4 197.3 45.8 252.4 123.6 13.2 101.2 118.7 63.6 205.8 77.0 68.6 10.5 60.1 17.9 85.5 139.6 117.4 23.3 37.2 77.6 79.0 23.4 269.7 30.5 61.7 179.6 AKT1S1 "Lobe, MGC2865, PRAS40" ENSG00000204673 "AKT1 substrate 1" Q96B36 19 49869033-49878459 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 130.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021903, HPA043590, HPA064427" Uncertain Supported Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB021903: , HPA043590: AB_2678569, HPA064427: AB_2685261" "unprognostic (2.11e-1)" "unprognostic (1.38e-1)" "unprognostic (2.64e-1)" "unprognostic (2.21e-1)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (3.70e-4)" "unprognostic (1.41e-2)" "unprognostic (1.41e-1)" "unprognostic (3.18e-1)" "prognostic favorable (6.60e-4)" "unprognostic (5.48e-2)" "prognostic unfavorable (7.34e-6)" "unprognostic (3.20e-2)" "unprognostic (2.84e-1)" "unprognostic (1.36e-1)" "unprognostic (3.65e-1)" 39.0 54.0 35.6 14.2 37.9 14.3 34.9 37.2 41.0 33.1 28.6 40.3 21.8 39.1 14.3 53.2 32.6 12.4 47.1 34.7 36.6 36.2 65.9 25.6 8.7 40.5 41.4 33.1 39.2 24.4 34.2 16.7 40.5 35.0 14.1 6.6 32.8 20.0 118.3 54.0 29.3 17.6 33.9 24.6 40.5 24.0 39.5 8.2 31.4 45.4 9.7 38.5 33.2 39.4 70.9 83.8 24.1 56.0 50.2 53.4 42.5 62.2 69.4 57.4 49.4 45.7 46.0 14.1 31.1 70.6 43.5 47.9 41.9 70.5 33.5 32.2 116.6 17.0 48.2 43.5 44.6 14.9 26.8 65.9 64.0 62.3 70.2 43.0 53.9 16.8 57.0 18.2 52.5 49.5 14.0 36.7 63.0 85.7 120.9 17.1 33.8 43.2 57.9 49.3 56.2 65.4 53.2 93.7 39.9 28.1 49.1 28.9 52.5 118.1 61.7 34.2 62.1 26.4 69.8 15.2 68.4 27.2 57.5 0.1 1.1 0.9 0.7 1.4 0.4 0.4 0.5 0.7 0.8 0.7 0.4 0.7 1.7 0.7 1.6 1.2 1.0 0.6 35.6 37.9 37.2 41.0 34.7 36.6 40.5 41.4 40.5 33.9 39.5 39.4 20.7 0.0 3.3 7.2 15.1 14.7 22.9 33.8 18.8 12.6 31.2 22.6 6.2 27.1 15.5 11.0 2.1 64.0 10.7 56.1 45.0 36.8 24.8 18.2 22.9 20.6 30.0 42.5 4.1 40.2 52.3 23.5 32.1 25.3 4.5 18.6 17.9 42.8 31.1 10.1 4.9 38.8 30.5 20.7 22.8 10.8 23.9 16.6 12.4 4.7 26.9 32.9 15.5 2.5 8.1 34.5 32.9 28.6 17.1 43.3 57.1 55.8 7.2 11.7 26.3 23.7 25.3 12.3 19.3 32.1 20.0 130.0 9.4 26.5 38.1 31.3 AKT3 "PKBG, PRKBG, RAC-gamma" ENSG00000117020 "AKT serine/threonine kinase 3" Q9Y243 1 243488233-243851079 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.9" "Group enriched" "Detected in many" 6 "Astrocytes: 457.4;Excitatory neurons: 756.1;Inhibitory neurons: 514.5;Microglial cells: 414.1;Oligodendrocyte precursor cells: 633.3;Oligodendrocytes: 475.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013090, HPA026441" Approved Supported Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "CAB013090: AB_2533692, HPA026441: AB_1844711" "unprognostic (1.33e-1)" "unprognostic (1.27e-1)" "unprognostic (2.40e-2)" "unprognostic (8.45e-2)" "unprognostic (1.89e-1)" "unprognostic (1.75e-1)" "unprognostic (1.96e-1)" "unprognostic (3.77e-1)" "unprognostic (2.32e-1)" "unprognostic (2.28e-1)" "unprognostic (5.47e-3)" "unprognostic (1.37e-1)" "unprognostic (6.71e-2)" "unprognostic (3.64e-3)" "unprognostic (1.29e-1)" "unprognostic (8.14e-2)" "prognostic unfavorable (9.27e-4)" 19.3 9.7 13.4 6.0 17.0 3.8 15.5 59.9 36.6 20.0 0.0 24.5 2.6 22.7 8.6 5.9 20.3 8.2 11.8 22.8 5.6 11.2 4.7 15.3 5.9 1.2 3.9 26.4 4.5 7.4 13.9 13.1 7.4 15.8 4.9 17.0 5.1 15.6 5.9 6.3 11.8 15.7 0.8 8.1 10.2 9.7 20.3 7.0 14.4 11.5 4.6 18.8 14.8 31.1 30.8 7.2 31.0 0.4 16.9 20.6 13.9 20.8 22.5 11.8 12.9 1.1 13.9 0.5 3.0 28.9 12.1 1.2 16.3 8.5 18.9 9.0 15.3 1.0 1.0 0.3 11.7 0.6 6.5 11.3 0.3 15.5 16.9 30.3 30.2 7.2 0.5 1.1 9.0 0.9 7.6 3.3 14.4 0.3 5.1 4.2 19.7 0.6 4.8 4.1 31.4 41.9 1.3 0.5 40.1 19.1 1.9 21.5 25.6 22.7 17.7 1.1 19.5 4.6 4.6 7.1 19.4 5.2 25.3 1.3 0.8 0.1 0.6 0.1 1.1 0.6 0.6 0.6 0.3 0.8 0.6 0.7 0.7 1.4 0.3 0.5 0.1 0.3 13.4 17.0 59.9 36.6 22.8 5.6 1.2 3.9 7.4 0.8 20.3 31.1 65.4 3.2 2.2 457.4 22.2 2.4 15.0 1.3 17.1 43.6 6.1 5.1 5.4 4.3 2.7 27.6 33.3 11.0 24.4 0.0 0.0 11.6 82.8 1.7 35.5 43.7 0.0 5.0 756.1 1.7 8.0 27.9 2.6 1.1 5.1 29.7 48.2 0.6 2.9 42.1 514.5 0.0 2.0 10.5 12.5 72.8 27.4 9.5 7.2 414.1 8.6 20.1 19.6 633.3 475.9 0.7 0.0 35.3 14.4 27.0 0.0 6.9 0.3 35.0 19.7 40.1 35.6 15.0 14.6 1.7 1.7 12.4 27.8 8.3 0.0 12.2 AL441992.2 ENSG00000286112 "Kynurenine aminotransferase 1" 9 128819663-128881931 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in some" "HPA021176, HPA021177, HPA027736" Uncertain Approved Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" Cytosol "HPA021176: AB_1846120, HPA021177: AB_1846119, HPA027736: AB_10611818" 0.3 0.1 0.6 0.2 0.7 0.5 0.2 1.5 1.9 0.2 0.5 0.2 0.2 0.3 0.5 0.2 0.3 0.2 0.1 0.6 0.3 0.1 0.3 0.1 0.3 0.4 0.3 0.3 0.2 0.1 0.3 0.4 0.3 0.1 1.1 0.2 0.4 0.5 0.4 0.1 0.2 0.2 0.2 0.1 0.3 0.5 0.3 0.1 0.4 0.2 0.2 1.3 0.4 1.5 1.0 0.6 1.2 0.4 1.2 1.0 0.1 0.7 0.6 1.1 0.4 1.1 0.5 0.6 0.7 1.2 0.6 1.1 0.1 0.9 1.3 1.0 1.4 0.8 0.2 0.9 0.4 0.4 0.5 0.9 0.4 0.7 0.3 1.0 1.6 0.2 0.2 0.5 0.9 0.7 0.9 1.3 1.1 1.2 1.1 0.3 0.2 0.3 0.6 1.0 0.9 0.0 0.2 0.7 0.2 0.3 1.0 0.7 0.6 0.3 0.7 1.2 2.6 0.9 0.3 0.7 0.3 0.8 0.9 0.2 1.0 0.3 0.9 1.4 0.7 0.7 0.7 1.1 0.8 0.8 0.6 1.3 0.5 1.9 0.8 0.5 0.6 0.7 1.5 1.9 0.6 0.3 0.4 0.3 0.4 0.2 0.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ALAD "ALADH, PBGS" ENSG00000148218 "Aminolevulinate dehydratase" P13716 9 113386312-113401290 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" "Allosteric enzyme, Lyase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 209.8" "Cell type enhanced" "Detected in all" "Erythroid cells: 147.8;Granulosa cells: 86.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021023, HPA022124" Enhanced Approved Cytosol NA NA 44000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" Cytosol "HPA021023: AB_1844716, HPA022124: AB_1844717" "unprognostic (2.75e-1)" "unprognostic (6.26e-2)" "prognostic unfavorable (7.33e-5)" "prognostic favorable (5.64e-4)" "unprognostic (4.16e-2)" "unprognostic (9.49e-2)" "prognostic favorable (8.80e-5)" "unprognostic (2.87e-3)" "unprognostic (3.49e-1)" "unprognostic (2.95e-1)" "unprognostic (1.62e-1)" "unprognostic (3.31e-2)" "prognostic favorable (1.65e-4)" "unprognostic (1.75e-1)" "unprognostic (1.22e-1)" "unprognostic (3.40e-1)" "unprognostic (1.31e-2)" 54.7 153.9 73.5 16.8 82.7 82.2 23.2 75.2 84.7 18.4 53.6 25.7 29.5 16.3 26.6 35.0 15.6 27.4 51.9 66.0 74.5 73.2 209.8 20.6 15.6 85.4 83.5 28.9 46.5 73.2 15.9 24.9 84.5 34.1 24.5 19.0 98.6 24.2 28.8 38.9 26.6 17.6 80.1 13.6 50.4 13.1 81.1 20.3 25.9 23.9 18.7 18.4 19.3 83.7 8.1 14.8 11.0 15.7 71.2 48.4 67.8 21.9 35.4 13.7 17.2 19.2 16.7 11.7 12.7 30.3 11.0 29.1 8.1 14.6 8.3 29.5 10.2 22.0 18.2 26.2 16.4 21.2 19.0 41.2 10.8 12.7 5.5 53.9 27.1 18.6 8.9 16.5 23.7 61.8 23.8 21.2 5.4 57.9 27.4 19.5 18.7 19.8 21.4 16.6 10.2 9.4 27.2 32.5 20.1 19.2 34.1 23.7 30.7 12.5 9.3 25.1 12.4 23.8 26.0 9.8 34.1 18.9 13.6 10.2 13.7 23.6 11.3 15.5 6.0 6.8 9.3 6.0 14.6 10.2 8.7 9.9 6.2 6.9 17.4 6.0 10.8 9.7 73.5 82.7 75.2 84.7 66.0 74.5 85.4 83.5 84.5 80.1 81.1 83.7 7.2 16.0 15.6 18.6 10.4 7.0 8.9 7.1 8.0 12.9 16.7 11.6 50.3 25.8 12.0 14.7 27.1 48.2 7.4 27.7 13.7 20.3 5.4 17.7 9.2 11.5 9.1 147.8 10.0 26.3 23.2 10.2 15.3 27.7 14.5 86.5 11.0 70.0 17.0 5.0 10.7 12.5 10.2 15.1 6.4 10.8 11.8 12.4 12.4 9.4 12.4 6.4 8.2 7.1 20.0 15.0 35.3 14.7 11.0 7.6 32.6 59.0 10.6 15.7 6.6 8.9 24.6 6.8 9.5 22.6 9.1 11.4 8.8 11.7 16.7 9.2 ALDH1A1 "ALDH1, PUMB1, RALDH1" ENSG00000165092 "Aldehyde dehydrogenase 1 family member A1" P00352 9 72900671-73080442 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 1500.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 389.4;Hepatocytes: 624.4;Leydig cells: 406.4;Proximal tubular cells: 375.4;Respiratory ciliated cells: 583.7" "Cancer enhanced" "Detected in all" "liver cancer: 399.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "classical monocyte: 87.3" "Lineage enriched" "Detected in many" 33 "monocytes: 87.3" "Cell line enhanced" "Detected in many" "A549: 4019.8;Hep G2: 1269.3;RPTEC TERT1: 710.6" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "midbrain: 378.3" "HPA002123, CAB020690" Enhanced Approved Enhanced Cytosol NA NA 58000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 2: Hepatocytes - Metabolism" Cytosol "CAB020690: , HPA002123: AB_1844722" "unprognostic (8.46e-3)" "prognostic favorable (7.77e-5)" "unprognostic (5.59e-2)" "unprognostic (1.69e-1)" "unprognostic (1.49e-2)" "unprognostic (8.71e-2)" "unprognostic (3.64e-2)" "unprognostic (3.98e-2)" "unprognostic (4.53e-2)" "unprognostic (6.83e-2)" "unprognostic (4.45e-2)" "unprognostic (3.73e-1)" "unprognostic (3.24e-3)" "unprognostic (2.20e-1)" "unprognostic (2.36e-1)" "unprognostic (2.96e-2)" "unprognostic (1.90e-3)" 109.4 182.4 51.3 28.4 71.9 31.8 64.3 125.1 72.4 121.8 35.7 218.2 549.7 139.3 583.4 41.3 184.3 175.4 53.7 64.6 62.1 335.4 1500.8 142.6 31.2 93.4 370.7 222.7 498.1 24.3 164.4 32.0 84.7 57.2 88.8 0.4 104.5 245.4 66.7 17.2 304.3 117.0 104.2 77.5 568.5 149.5 74.5 19.8 211.7 83.0 21.6 31.6 90.7 106.1 0.0 4019.8 0.4 0.0 22.4 0.2 1.4 139.6 0.0 0.1 0.1 136.2 0.0 0.1 50.5 0.0 0.3 2.6 0.0 0.2 0.1 0.4 0.1 232.1 0.6 1269.3 13.7 0.6 0.3 6.7 0.1 0.0 0.0 0.3 143.0 0.0 16.9 0.0 153.3 7.2 0.2 1.8 0.7 7.2 0.4 0.5 44.0 1.8 710.6 1.1 0.3 1.4 0.3 0.4 2.9 0.2 0.0 0.5 0.7 0.0 3.5 0.5 0.3 0.4 0.2 1.0 0.0 1.7 0.4 0.0 87.3 1.4 0.0 14.9 0.0 0.0 0.2 0.1 1.4 0.7 0.0 0.0 2.6 0.0 1.1 1.0 0.0 30.3 51.3 71.9 125.1 72.4 64.6 62.1 93.4 370.7 84.7 104.2 74.5 106.1 4.9 96.1 107.6 31.3 6.9 2.7 18.3 168.3 1.2 0.4 12.6 1.7 4.3 187.3 361.1 115.8 0.0 1.7 0.1 20.2 389.4 71.6 12.6 6.3 125.2 26.4 54.9 96.1 3.5 349.7 1.0 102.7 258.4 8.1 158.9 0.2 133.5 624.4 134.4 0.0 0.5 168.9 138.4 109.6 5.1 37.8 406.4 61.7 7.2 17.8 46.0 0.0 2.1 0.0 0.7 128.4 77.4 207.3 1.3 2.0 267.4 375.4 583.7 0.3 26.3 334.2 28.6 8.6 4.6 21.5 3.1 2.5 8.8 129.6 131.7 26.5 ALDH1L1 "10-fTHF, FDH, FTHFD" ENSG00000144908 "Aldehyde dehydrogenase 1 family member L1" O75891 3 126103562-126197994 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 369.7" "Group enriched" "Detected in many" 4 "Hepatocytes: 633.3;Proximal tubular cells: 197.4" "Cancer enriched" "Detected in many" 4 "liver cancer: 40.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 36.5;Hep G2: 78.1;Karpas-707: 82.0;RPMI-8226: 45.0;RT4: 219.1;U-266/70: 44.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036900, HPA050139" Enhanced Supported Supported Cytosol No No 3000000 "Cluster 15: Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" Cytosol "HPA036900: AB_10672273, HPA050139: AB_2681031" "unprognostic (5.93e-2)" "unprognostic (1.22e-1)" "unprognostic (9.12e-2)" "unprognostic (2.68e-1)" "unprognostic (1.10e-1)" "unprognostic (1.10e-1)" "unprognostic (7.12e-2)" "unprognostic (1.29e-1)" "unprognostic (3.05e-2)" "unprognostic (4.73e-2)" "unprognostic (3.05e-3)" "unprognostic (8.40e-2)" "prognostic favorable (2.42e-8)" "unprognostic (3.60e-1)" "unprognostic (1.47e-1)" "unprognostic (7.03e-3)" "unprognostic (7.93e-2)" 76.4 37.2 53.4 2.0 63.2 0.4 28.8 55.9 63.6 15.6 37.7 10.1 0.2 7.2 2.5 6.6 16.0 2.3 26.5 47.5 56.2 116.6 369.7 3.1 0.3 56.7 52.9 45.3 44.3 15.1 4.5 0.0 53.0 14.6 5.4 8.7 88.6 6.9 90.7 3.5 5.6 2.0 48.4 0.4 9.5 15.0 53.9 3.7 2.6 59.9 4.6 28.3 6.4 46.0 1.3 0.0 0.0 0.0 36.5 0.0 0.4 0.3 1.5 0.4 0.6 0.0 3.2 2.6 10.2 0.0 2.1 0.4 0.6 1.5 0.7 0.0 0.2 0.1 0.3 78.1 10.6 10.6 0.2 0.3 0.8 0.0 0.0 0.3 0.0 0.0 0.0 82.0 1.6 0.0 0.0 0.2 0.3 1.1 0.0 0.1 0.2 45.0 0.7 219.1 0.4 0.3 1.3 10.6 0.0 0.6 0.1 0.0 0.3 1.4 6.2 0.0 0.1 44.8 14.8 0.4 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.4 63.2 55.9 63.6 47.5 56.2 56.7 52.9 53.0 48.4 53.9 46.0 0.8 0.0 6.0 92.7 4.6 0.1 53.5 9.1 1.8 0.2 14.4 2.2 16.1 38.6 44.0 12.9 0.0 0.0 0.1 7.2 72.4 2.9 22.3 57.2 5.2 4.6 1.2 34.7 0.6 5.6 0.2 9.1 0.0 3.6 27.8 12.4 17.2 633.3 0.1 0.0 3.0 17.6 2.0 24.5 1.9 35.0 26.4 9.3 3.6 3.7 0.0 40.0 0.0 11.1 0.2 2.2 0.4 22.6 0.0 12.2 0.8 197.4 32.2 1.4 6.6 10.5 5.3 1.6 4.3 1.7 0.0 0.1 2.8 0.9 5.6 61.7 ALDH9A1 "ALDH4, ALDH7, ALDH9, E3" ENSG00000143149 "Aldehyde dehydrogenase 9 family member A1" P49189 1 165662216-165698863 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 311.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA006077, HPA010873" Approved Approved Cytosol "Intracellular and membrane" NA NA 2000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA006077: , HPA010873: AB_1078126" "unprognostic (2.24e-1)" "unprognostic (3.16e-2)" "unprognostic (4.17e-2)" "unprognostic (1.25e-1)" "unprognostic (3.21e-2)" "unprognostic (1.25e-1)" "unprognostic (4.14e-2)" "unprognostic (4.87e-2)" "unprognostic (2.30e-1)" "unprognostic (1.83e-1)" "prognostic favorable (4.56e-4)" "unprognostic (5.51e-2)" "unprognostic (9.05e-2)" "unprognostic (1.67e-1)" "unprognostic (1.49e-1)" "unprognostic (1.43e-1)" "unprognostic (2.15e-1)" 119.2 105.5 49.6 29.8 51.0 24.8 76.8 49.3 60.3 51.5 62.5 45.7 54.8 38.6 93.4 105.6 50.2 32.0 48.2 47.4 57.5 142.4 206.5 38.5 40.3 50.5 52.1 53.6 44.0 81.9 39.9 38.0 51.4 65.3 50.6 46.4 104.1 45.6 93.6 54.7 48.6 42.0 50.7 37.9 39.5 63.4 49.3 39.0 123.0 56.4 60.1 39.4 43.9 55.6 55.7 53.5 48.7 44.1 152.1 132.8 40.7 71.9 101.5 70.8 61.0 33.4 40.7 0.1 67.1 64.8 34.9 42.8 40.0 70.3 83.0 25.9 50.6 35.3 34.7 36.5 78.2 56.0 36.1 86.0 34.8 75.2 62.5 97.8 62.2 45.9 56.9 48.4 111.7 33.4 37.6 57.6 71.3 145.1 64.7 31.7 62.0 74.3 92.5 52.0 57.7 39.8 51.4 57.1 67.4 65.6 108.8 84.0 61.9 42.5 41.5 52.4 37.1 44.7 62.5 54.8 47.9 52.6 41.7 61.8 35.2 50.9 45.5 37.7 48.8 49.9 43.8 49.6 34.5 46.8 43.8 50.4 51.3 43.0 45.3 21.6 69.8 45.6 49.6 51.0 49.3 60.3 47.4 57.5 50.5 52.1 51.4 50.7 49.3 55.6 56.2 16.0 47.6 12.7 43.3 32.6 43.3 43.8 68.3 25.0 83.0 54.6 46.5 55.8 36.8 51.5 22.9 48.5 39.3 43.9 97.8 42.9 45.4 27.7 39.1 49.4 55.8 28.2 5.6 37.0 76.4 60.6 36.2 20.4 38.0 60.9 59.3 158.8 61.9 13.5 8.3 56.9 32.6 59.1 24.9 39.8 95.4 43.8 56.9 6.5 34.6 311.5 39.1 12.1 12.2 32.2 33.1 115.5 34.8 39.6 80.3 204.4 59.4 28.9 26.3 32.5 40.1 85.6 49.9 123.8 51.9 38.2 43.7 148.4 63.6 28.3 ALDOA ENSG00000149925 "Aldolase, fructose-bisphosphate A" P04075 16 30064164-30070457 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes, Disease variant, Glycogen storage disease, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "skeletal muscle: 26754.8;tongue: 9180.4" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 3267.9;Extravillous trophoblasts: 2322.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004177, CAB006252" Supported Approved Cytosol NA NA 640000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "CAB006252: AB_437007, HPA004177: AB_1078128" "unprognostic (2.63e-2)" "unprognostic (3.22e-2)" "unprognostic (6.80e-2)" "unprognostic (1.33e-1)" "unprognostic (6.74e-3)" "unprognostic (4.28e-3)" "prognostic unfavorable (5.79e-5)" "prognostic unfavorable (7.32e-5)" "unprognostic (1.68e-1)" "unprognostic (1.81e-1)" "unprognostic (2.30e-2)" "unprognostic (1.57e-1)" "unprognostic (1.81e-1)" "unprognostic (1.28e-1)" "unprognostic (1.22e-1)" "unprognostic (2.19e-3)" "unprognostic (4.48e-2)" 569.3 696.4 616.8 443.1 697.4 732.5 512.6 617.3 719.7 566.0 617.0 774.1 517.9 533.7 201.0 1302.0 449.7 420.5 2286.1 731.9 652.0 709.0 217.1 425.6 358.2 762.3 654.0 510.4 390.5 943.1 525.1 351.4 763.9 457.7 400.1 465.2 904.9 597.6 26754.8 643.4 488.3 465.2 545.5 417.5 595.0 138.7 657.8 280.9 454.5 9180.4 478.3 761.8 740.3 558.7 2206.1 1620.4 477.9 1542.8 714.6 808.5 1520.8 1297.9 1336.2 1291.6 1603.0 1158.1 1643.6 1487.6 2072.2 1318.6 708.6 1632.6 966.8 2829.1 939.3 658.5 1272.9 1219.3 1202.7 2591.1 1112.5 1793.8 1251.3 1115.7 979.6 1455.4 968.9 2119.7 965.4 686.9 1070.0 951.1 1393.4 3136.7 1100.2 1477.0 1192.8 848.1 1346.6 1613.9 765.2 3353.2 1629.4 1230.5 950.7 668.5 808.6 3368.5 1213.9 591.2 1433.0 1194.7 1162.5 1892.3 750.3 1046.7 1430.0 1861.5 1387.3 1369.3 3524.5 1715.9 1532.9 2050.6 2694.7 2081.7 1008.7 2466.5 1138.1 908.5 1091.7 1047.0 2182.7 877.9 1027.4 996.9 2531.7 819.9 2780.2 824.0 1476.3 4372.2 616.8 697.4 617.3 719.7 731.9 652.0 762.3 654.0 763.9 545.5 657.8 558.7 17.0 12.8 32.4 83.2 281.2 792.0 716.4 3267.9 784.8 387.4 34.4 21.6 1968.4 273.1 1385.1 42.3 118.9 1194.1 107.9 1834.8 111.6 120.9 258.8 15.8 11.8 261.1 323.9 215.8 66.2 76.2 2322.1 329.7 513.3 16.1 196.5 18.7 289.5 102.0 1181.9 733.6 70.0 755.1 1265.4 632.2 715.4 1152.4 380.8 388.8 924.9 50.6 417.7 662.1 328.5 40.2 60.8 126.2 1497.1 405.1 409.4 676.9 1755.7 75.8 700.9 298.9 486.4 680.9 572.9 25.8 123.6 1174.6 684.5 1361.3 294.3 15.2 937.7 1146.2 ALG5 bA421P11.2 ENSG00000120697 "ALG5 dolichyl-phosphate beta-glucosyltransferase" Q9Y673 13 36949738-37000763 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007989 Approved Approved Cytosol No No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "HPA007989: AB_1078132" "unprognostic (1.87e-1)" "unprognostic (1.73e-2)" "unprognostic (6.07e-2)" "unprognostic (1.05e-3)" "unprognostic (3.01e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.57e-2)" "unprognostic (5.82e-2)" "unprognostic (5.21e-2)" "unprognostic (7.46e-2)" "unprognostic (3.51e-2)" "unprognostic (3.30e-1)" "prognostic favorable (1.40e-5)" "unprognostic (7.44e-2)" "unprognostic (1.66e-1)" "unprognostic (7.14e-3)" "unprognostic (1.86e-1)" 29.1 32.3 12.1 19.6 13.3 26.9 41.6 13.4 25.7 34.2 14.9 36.0 27.1 23.5 77.9 21.7 23.3 23.2 18.5 12.4 13.7 41.2 61.9 24.5 20.7 13.5 13.1 20.6 90.1 40.2 18.7 25.4 14.0 26.5 46.4 11.2 51.9 30.9 18.5 20.9 27.6 23.4 13.6 23.6 36.6 15.2 12.6 22.7 54.9 10.5 28.9 30.5 21.6 14.8 24.3 35.0 31.5 29.4 95.1 61.8 22.5 63.9 81.1 63.7 53.7 71.0 84.1 35.2 25.9 45.7 55.0 57.5 41.9 55.0 62.6 37.4 77.7 77.2 27.5 40.1 85.1 69.6 43.7 62.7 88.8 49.4 60.6 41.5 47.7 43.9 39.8 49.7 59.9 45.6 47.4 59.8 29.1 188.2 27.5 54.3 30.4 102.5 71.5 49.8 25.2 45.5 29.2 62.8 34.2 25.4 34.4 79.1 36.1 32.7 20.4 37.2 45.8 35.8 28.8 37.4 51.2 41.9 57.1 59.1 55.7 26.2 53.4 62.3 54.4 44.1 49.1 55.6 57.1 40.2 46.4 47.2 5.8 54.7 53.0 109.0 65.7 69.2 12.1 13.3 13.4 25.7 12.4 13.7 13.5 13.1 14.0 13.6 12.6 14.8 52.0 51.3 51.9 11.1 51.5 34.7 45.9 142.9 27.3 19.8 50.2 42.5 14.2 61.5 86.0 53.3 10.4 81.4 49.4 28.9 23.5 93.5 33.7 31.5 44.1 45.5 36.1 25.9 19.5 140.2 74.4 46.0 32.1 40.1 29.2 25.9 37.9 77.3 69.7 11.8 22.4 76.3 111.9 37.1 52.1 25.8 40.0 39.4 80.0 14.0 45.2 36.6 25.7 18.1 30.6 85.9 50.9 38.4 166.6 56.4 51.4 62.7 43.8 25.2 46.0 34.4 70.7 57.6 23.7 33.6 30.3 81.3 43.0 58.5 62.2 50.7 ALPK2 HAK ENSG00000198796 "Alpha kinase 2" Q86TB3 18 58481247-58629091 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "heart muscle: 41.9;skeletal muscle: 38.3;tongue: 33.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 120.4;Cone photoreceptor cells: 47.9;Early spermatids: 15.9;Late spermatids: 24.3;monocytes: 18.1" "Cancer enriched" "Detected in some" 6 "renal cancer: 7.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 51.2;BJ hTERT+: 31.0;fHDF/TERT166: 46.6;U-138 MG: 25.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027377, HPA027976, HPA028084, HPA029801" Uncertain Approved Cytosol NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "HPA027377: AB_10600635, HPA027976: AB_10611246, HPA028084: AB_10601996, HPA029801: AB_10602006" "unprognostic (7.35e-2)" "unprognostic (4.91e-2)" "unprognostic (1.64e-1)" "unprognostic (4.60e-3)" "unprognostic (2.64e-1)" "unprognostic (8.27e-2)" "unprognostic (1.22e-1)" "unprognostic (1.41e-1)" "unprognostic (3.44e-1)" "unprognostic (1.06e-1)" "unprognostic (5.13e-2)" "unprognostic (1.33e-2)" "prognostic unfavorable (8.20e-5)" "unprognostic (5.27e-3)" "unprognostic (2.50e-1)" "unprognostic (4.73e-2)" "unprognostic (3.20e-2)" 0.8 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.8 0.3 0.0 0.9 41.9 0.4 0.0 9.2 4.5 0.1 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.2 2.1 0.3 0.0 38.3 0.5 1.0 0.1 0.0 0.5 1.7 1.1 0.0 3.5 0.0 33.2 4.4 1.5 0.0 0.0 0.0 13.7 0.9 0.0 0.4 3.4 0.3 51.2 31.0 21.2 18.1 3.4 0.0 0.0 5.2 46.6 2.9 0.0 0.0 0.0 21.5 11.5 0.0 0.0 4.4 1.8 2.7 0.0 0.0 3.0 0.0 6.4 0.2 0.7 0.0 0.0 0.0 0.4 13.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 11.1 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 8.3 0.0 0.0 0.0 25.3 11.2 3.5 8.7 20.9 19.2 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.7 0.1 0.0 0.0 0.0 0.2 0.1 4.8 120.4 0.0 0.0 0.0 47.9 0.0 0.1 0.0 1.9 1.5 15.9 0.0 2.3 0.9 0.0 0.0 1.0 0.7 0.0 8.9 0.0 0.1 0.0 4.0 0.4 3.0 0.7 1.7 0.7 0.0 0.0 0.3 3.0 24.3 0.3 2.4 0.0 0.0 18.1 2.6 0.0 0.0 0.8 0.2 2.3 0.0 0.6 0.0 0.3 13.6 0.0 0.9 0.0 3.8 1.7 1.1 0.1 0.0 0.9 0.1 0.3 0.0 0.0 0.0 ALPL "HOPS, TNALP, TNAP, TNSALP" ENSG00000162551 "Alkaline phosphatase, biomineralization associated" P05186 1 21509397-21578410 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Biomineralization Hydrolase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 60.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 92.0;Breast myoepithelial cells: 32.4;Glandular and luminal cells: 43.3;Hepatic stellate cells: 40.7;Hepatocytes: 30.1;Proximal tubular cells: 43.9;Rod photoreceptor cells: 34.2" "Cancer enhanced" "Detected in all" "testis cancer: 199.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 90 "neutrophil: 379.1" "Lineage enriched" "Detected in many" 139 "granulocytes: 379.1" "Cell line enhanced" "Detected in many" "HSkMC: 176.9;hTEC/SVTERT24-B: 141.2;LHCN-M2: 103.7;NTERA-2: 41.2;SCLC-21H: 88.2;SuSa: 48.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007105, HPA008765, CAB020829" Enhanced Approved Cytosol "Intracellular and membrane" NA NA 13000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 11: Alveolar cells - Smell perception" Cytosol "CAB020829: , HPA007105: AB_1078137, HPA008765: AB_1078138" "unprognostic (3.89e-2)" "unprognostic (1.27e-1)" "unprognostic (5.57e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (7.57e-4)" "unprognostic (3.05e-3)" "unprognostic (6.50e-3)" "unprognostic (1.01e-1)" "prognostic unfavorable (7.08e-4)" "unprognostic (1.17e-2)" "unprognostic (2.48e-3)" "unprognostic (1.74e-1)" "unprognostic (7.28e-2)" "unprognostic (1.73e-2)" "unprognostic (2.27e-1)" "unprognostic (9.70e-3)" "unprognostic (2.58e-1)" 24.7 60.7 19.5 27.9 16.7 4.2 22.9 18.0 25.8 3.4 26.0 5.0 2.6 5.8 1.3 4.1 10.4 3.9 16.4 17.8 18.8 45.7 56.3 54.9 6.4 21.7 17.7 2.8 3.9 3.3 9.3 3.1 22.4 7.1 1.5 18.8 6.4 9.2 1.1 4.2 7.5 3.5 18.2 45.5 4.7 4.2 21.3 1.5 8.6 5.7 5.9 9.7 3.3 17.3 0.0 0.2 5.2 0.2 0.8 6.6 11.4 0.4 2.4 0.9 1.5 1.0 0.0 2.4 7.7 0.0 0.1 0.1 31.3 0.2 0.6 0.0 2.1 0.0 3.5 3.9 1.8 0.0 0.7 176.9 0.0 141.2 0.5 0.0 0.0 0.0 0.2 0.0 103.7 0.0 0.1 0.0 41.2 0.2 0.0 0.0 3.8 0.2 0.1 0.0 88.2 1.2 0.0 0.1 0.3 48.1 0.2 0.0 0.0 5.2 4.3 0.1 0.0 0.3 0.0 0.1 0.9 0.0 0.8 0.0 0.0 4.2 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.5 0.0 0.0 379.1 0.0 0.0 0.0 0.0 0.1 19.5 16.7 18.0 25.8 17.8 18.8 21.7 17.7 22.4 18.2 21.3 17.3 25.9 3.2 92.0 0.3 3.8 0.1 0.6 8.2 0.6 2.5 6.6 32.4 2.1 2.8 17.6 0.0 0.0 0.1 0.1 0.0 7.9 0.0 1.4 15.0 2.2 26.5 0.0 5.7 0.9 0.0 0.3 6.8 0.0 43.3 7.6 10.6 40.7 30.1 0.1 1.7 0.3 0.0 12.2 1.6 0.3 8.5 0.3 1.0 0.0 18.7 0.0 6.0 0.0 6.0 0.2 0.0 0.0 0.0 0.3 1.7 0.0 43.9 3.6 34.2 0.0 0.3 5.1 0.4 14.0 0.2 0.4 1.5 1.0 8.0 0.0 0.3 AMPD2 SPG63 ENSG00000116337 "Adenosine monophosphate deaminase 2" Q01433 1 109616104-109632051 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 62.6;Horizontal cells: 52.2;Macrophages: 52.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 19.4;eosinophil: 19.2;intermediate monocyte: 40.7;myeloid DC: 18.9;neutrophil: 61.1;non-classical monocyte: 44.6" "Group enriched" "Detected in all" 5 "dendritic cells: 18.9;granulocytes: 61.1;monocytes: 44.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027137, HPA045760" Approved Enhanced Cytosol NA NA 230000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Cytosol "HPA027137: AB_2672129, HPA045760: AB_2679443" "unprognostic (2.78e-2)" "unprognostic (1.21e-1)" "unprognostic (1.50e-1)" "unprognostic (1.43e-3)" "unprognostic (9.01e-2)" "unprognostic (5.25e-2)" "unprognostic (3.91e-3)" "unprognostic (1.71e-1)" "unprognostic (4.02e-1)" "unprognostic (1.23e-1)" "unprognostic (8.10e-3)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.78e-10)" "unprognostic (9.16e-2)" "unprognostic (2.03e-1)" "unprognostic (1.35e-2)" "unprognostic (1.60e-1)" 9.3 17.5 31.2 12.0 41.6 28.6 7.4 22.9 34.7 13.1 36.6 7.5 10.7 11.5 4.1 7.2 13.1 8.8 7.2 34.8 37.0 10.5 16.2 13.4 7.6 34.7 31.7 17.5 10.0 9.4 45.8 7.6 33.6 10.8 4.1 10.5 9.2 12.0 3.3 8.5 10.8 7.1 27.9 19.0 8.6 4.3 39.3 4.9 10.6 1.5 5.9 7.5 11.4 29.0 20.6 22.5 20.5 20.1 18.0 18.7 8.6 25.6 57.2 24.9 25.0 19.1 7.0 10.5 21.8 39.1 16.0 11.3 15.8 20.0 13.4 13.0 20.7 46.0 15.6 19.3 24.9 15.7 45.7 23.3 13.2 32.5 24.1 28.2 26.7 17.0 17.4 13.0 16.0 23.2 26.7 29.0 20.6 17.1 22.9 18.6 15.8 17.3 24.2 8.7 19.3 22.4 17.4 19.8 24.6 5.7 10.4 16.2 16.7 27.7 39.0 33.7 25.4 48.4 28.4 12.1 50.8 25.9 35.1 0.5 19.4 19.2 5.3 40.7 8.0 5.3 5.2 4.9 18.9 2.7 6.4 5.1 61.1 4.3 44.6 2.6 4.0 12.3 31.2 41.6 22.9 34.7 34.8 37.0 34.7 31.7 33.6 27.9 39.3 29.0 3.6 3.2 5.5 13.7 9.4 8.9 5.4 5.0 9.1 41.0 8.8 11.4 3.2 12.8 5.4 0.0 62.6 4.9 10.0 4.2 7.9 9.8 3.5 4.4 9.4 7.1 17.5 5.0 13.3 11.2 8.6 12.6 14.3 5.5 3.8 11.0 6.1 20.5 10.8 52.2 17.6 9.6 2.0 42.1 42.0 1.3 13.1 52.5 5.4 6.5 16.1 10.5 6.2 12.1 10.6 10.3 3.0 21.4 11.1 11.1 6.1 4.5 4.2 7.2 13.1 8.8 10.6 4.2 3.8 7.9 8.1 2.6 15.4 8.5 10.7 4.0 ANAPC16 "APC16, bA570G20.3, C10orf104, CENP-27, FLJ33728" ENSG00000166295 "Anaphase promoting complex subunit 16" Q96DE5 10 72216000-72235860 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 93.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037815 Approved Supported Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA037815: AB_10672288" "unprognostic (2.87e-1)" "unprognostic (4.35e-3)" "unprognostic (2.01e-2)" "unprognostic (7.12e-3)" "unprognostic (2.16e-1)" "unprognostic (6.20e-3)" "unprognostic (1.51e-2)" "unprognostic (2.00e-1)" "unprognostic (1.82e-1)" "unprognostic (3.10e-2)" "unprognostic (1.90e-2)" "unprognostic (2.11e-1)" "unprognostic (2.75e-3)" "unprognostic (7.77e-2)" "unprognostic (1.25e-1)" "unprognostic (1.03e-1)" "unprognostic (1.35e-3)" 20.5 25.2 12.4 15.0 13.4 14.1 21.9 16.6 15.2 19.7 15.5 23.6 15.7 18.2 22.3 14.9 23.5 12.6 43.6 12.5 12.8 24.2 27.2 18.9 25.4 13.6 12.8 24.3 33.7 33.1 15.9 11.9 13.4 21.5 17.9 20.6 32.3 21.8 62.7 15.0 19.6 17.8 12.4 22.7 25.8 8.4 13.1 32.3 23.5 43.2 25.7 19.5 15.1 14.6 24.9 12.1 12.1 14.3 33.0 15.7 9.3 8.5 17.3 11.7 11.0 14.6 31.1 24.3 13.6 12.7 14.1 19.0 10.9 21.9 11.0 29.0 18.0 12.5 10.6 14.4 39.6 21.0 14.7 20.5 93.9 10.6 34.8 25.8 14.3 35.1 18.4 28.1 13.6 15.0 17.9 21.1 9.3 18.2 6.8 10.2 10.8 24.2 29.4 10.4 17.4 16.0 14.8 37.9 29.5 15.2 12.2 21.9 18.6 5.9 13.8 9.5 13.1 28.6 26.8 25.1 16.4 40.3 7.0 41.1 21.5 38.8 31.4 23.1 35.2 60.5 35.2 31.3 18.1 66.1 48.6 38.6 19.7 34.4 24.9 45.7 34.7 36.3 12.4 13.4 16.6 15.2 12.5 12.8 13.6 12.8 13.4 12.4 13.1 14.6 191.0 157.0 209.5 41.8 303.7 111.7 246.7 322.0 150.8 81.0 288.6 316.5 435.4 280.2 234.9 222.5 37.5 198.4 240.1 166.8 684.8 239.8 91.9 188.9 98.9 179.8 161.8 155.0 47.8 291.9 191.2 142.0 108.1 145.9 202.0 110.1 203.1 481.3 226.5 33.7 57.2 258.0 254.3 310.0 111.9 53.4 233.6 160.4 193.9 36.5 322.4 192.4 363.5 43.2 75.9 196.9 239.9 250.1 208.2 218.1 262.6 548.7 217.0 144.5 230.1 162.0 219.9 158.7 126.2 189.9 140.9 149.3 268.6 145.6 214.1 240.9 ANKH "ANK, CCAL2, CMDJ, CPPDD, HANK, SLC62A1" ENSG00000154122 "ANKH inorganic pyrophosphate transport regulator" Q9HCJ1 5 14704800-14871778 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Phosphate transport, Transport" "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 160.1;Hofbauer cells: 208.8;Inhibitory neurons: 214.5;Oligodendrocytes: 261.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068104 Approved Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA068104: AB_2685954" "unprognostic (1.15e-1)" "unprognostic (3.35e-1)" "unprognostic (1.55e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (5.62e-4)" "unprognostic (6.58e-2)" "unprognostic (3.53e-2)" "unprognostic (1.67e-1)" "unprognostic (2.83e-2)" "unprognostic (2.11e-1)" "unprognostic (2.38e-2)" "unprognostic (2.99e-1)" "unprognostic (1.54e-3)" "unprognostic (1.76e-3)" "unprognostic (1.71e-1)" "unprognostic (8.66e-2)" "unprognostic (6.46e-2)" 9.9 10.6 22.1 6.6 23.8 8.0 9.9 33.9 29.3 5.5 26.6 12.8 16.8 7.1 4.9 7.4 7.7 9.4 32.2 22.5 25.5 8.1 21.4 7.1 8.5 25.3 28.2 16.0 15.2 19.2 22.8 8.5 25.1 32.7 11.4 25.1 14.3 9.2 40.9 20.3 15.0 8.5 24.9 6.8 7.3 1.9 26.8 11.5 10.7 37.6 14.1 7.3 7.4 28.8 7.2 5.4 6.7 1.1 13.8 32.3 3.2 6.8 13.7 2.6 2.7 4.3 9.0 16.9 15.7 9.4 6.2 4.6 4.6 7.5 3.0 6.7 11.3 0.4 47.8 11.6 4.6 4.1 1.3 10.2 13.0 8.1 9.2 9.2 5.5 12.3 3.5 35.2 8.7 9.6 6.9 13.3 2.6 9.5 6.0 9.8 3.3 15.3 0.0 2.3 16.4 4.5 33.3 5.3 7.5 6.1 0.3 1.5 5.4 6.9 6.9 11.5 12.6 9.2 9.3 13.0 23.8 15.1 29.0 0.6 0.2 0.0 1.4 0.4 2.3 1.5 2.9 2.3 0.3 1.6 3.3 1.5 0.3 0.3 0.9 0.3 4.6 0.4 22.1 23.8 33.9 29.3 22.5 25.5 25.3 28.2 25.1 24.9 26.8 28.8 50.1 25.6 19.1 64.6 15.4 25.2 79.1 33.7 40.9 58.0 29.7 15.5 73.4 7.2 10.8 7.3 127.2 76.4 21.1 58.2 5.9 1.7 1.2 7.1 14.9 25.4 41.8 69.9 160.1 11.8 6.1 25.6 8.2 16.9 17.7 9.8 12.5 32.7 208.8 20.2 214.5 37.7 8.2 89.3 29.9 1.9 5.0 42.6 10.6 106.8 3.4 20.1 21.6 95.5 261.5 6.8 31.4 31.6 14.7 55.4 44.6 10.2 6.4 50.1 0.0 32.8 12.3 2.3 7.2 10.1 10.7 42.0 25.9 8.6 37.3 22.3 ANKRD34A ANKRD34 ENSG00000272031 "Ankyrin repeat domain 34A" Q69YU3 1 145959441-145964575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.1;skeletal muscle: 6.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 9.7;Excitatory neurons: 6.1;Inhibitory neurons: 5.8;Microglial cells: 3.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "RPMI-8226: 10.7;U-266/84: 7.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029642, HPA029643" Uncertain Enhanced Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 47: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 56: Bipolar cells - Visual perception" Cytosol "HPA029642: AB_10599277, HPA029643: AB_10601878" "unprognostic (1.98e-1)" "unprognostic (5.66e-2)" "unprognostic (1.90e-2)" "unprognostic (1.05e-1)" "unprognostic (2.26e-1)" "unprognostic (1.44e-2)" "unprognostic (4.36e-2)" "unprognostic (1.41e-1)" "unprognostic (2.51e-1)" "unprognostic (3.19e-1)" "unprognostic (2.15e-2)" "unprognostic (6.68e-3)" "unprognostic (9.66e-8)" "unprognostic (6.36e-2)" "unprognostic (9.01e-2)" "unprognostic (1.76e-1)" "unprognostic (9.23e-2)" 0.6 0.7 3.8 1.2 5.9 0.2 0.6 4.8 14.1 0.8 0.0 1.1 0.9 1.6 0.6 0.6 1.0 0.6 1.4 6.0 1.6 0.5 0.5 0.6 0.9 0.9 1.1 1.2 0.3 0.9 2.9 0.2 0.9 1.2 0.2 3.4 1.0 1.1 6.4 0.4 1.1 0.8 0.0 1.0 0.8 0.4 3.2 0.4 0.6 2.6 0.9 1.1 0.8 5.0 1.2 0.6 0.6 2.0 2.8 2.2 0.3 2.2 4.3 0.5 1.3 0.2 0.6 2.4 0.2 2.9 1.1 0.5 0.9 0.6 0.3 5.0 1.4 0.1 1.8 0.0 0.4 0.3 1.9 2.0 0.2 1.8 2.0 3.0 0.7 1.9 1.2 5.3 3.3 2.2 1.0 0.7 0.2 0.1 2.5 0.2 0.5 10.7 0.9 0.0 2.8 2.0 0.4 0.1 1.3 0.2 3.0 0.3 0.7 5.1 3.5 4.4 1.1 3.6 7.5 0.3 5.0 1.9 0.4 0.0 0.0 0.2 1.1 0.1 0.8 0.5 0.5 0.6 0.1 0.6 0.7 1.1 0.1 0.1 0.0 0.0 0.6 0.3 3.8 5.9 4.8 14.1 6.0 1.6 0.9 1.1 0.9 0.0 3.2 5.0 0.4 0.0 0.0 0.3 1.4 0.3 0.4 0.3 1.2 9.7 0.6 0.6 3.0 0.0 0.2 0.0 0.0 0.0 1.0 0.3 1.9 0.3 0.8 0.2 0.6 0.8 0.0 0.0 6.1 0.2 0.0 0.6 0.0 0.2 0.0 0.1 0.4 0.1 0.2 0.0 5.8 0.0 0.0 0.0 0.3 0.5 0.3 0.6 0.0 3.7 0.2 2.1 1.0 2.0 1.3 0.1 0.3 1.5 0.1 0.3 0.0 0.5 0.0 2.1 0.0 0.6 0.9 0.7 0.4 0.6 0.1 0.1 1.4 0.7 0.1 0.1 ANKRD46 ENSG00000186106 "Ankyrin repeat domain 46" Q86W74 8 100509752-100559784 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Horizontal cells: 67.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013758 Approved Approved Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 62: Horizontal cells - Visual perception" Cytosol "HPA013758: AB_10962626" "unprognostic (3.71e-3)" "unprognostic (9.01e-2)" "unprognostic (2.03e-1)" "unprognostic (2.22e-2)" "unprognostic (9.82e-2)" "unprognostic (1.16e-1)" "unprognostic (2.63e-1)" "unprognostic (8.84e-2)" "unprognostic (4.79e-2)" "unprognostic (3.56e-1)" "unprognostic (2.98e-2)" "unprognostic (1.51e-1)" "unprognostic (8.08e-3)" "unprognostic (5.29e-2)" "unprognostic (1.82e-1)" "unprognostic (1.81e-2)" "unprognostic (6.29e-3)" 19.2 38.7 29.1 8.4 30.2 2.2 14.6 25.1 33.6 15.1 15.6 9.2 10.2 12.7 16.3 12.7 11.4 7.7 20.1 30.1 25.8 32.7 41.6 10.7 9.9 22.3 22.2 22.6 18.5 16.1 10.3 20.8 24.4 13.5 9.1 35.2 17.1 13.2 62.2 11.2 11.0 12.4 24.9 11.1 11.6 8.3 24.0 15.4 20.0 36.2 10.9 9.5 9.9 28.7 10.0 12.2 17.9 10.1 13.6 8.0 20.0 12.8 5.8 9.6 8.1 17.8 5.9 31.2 23.3 4.4 3.1 7.5 18.5 9.5 10.1 11.2 16.3 39.0 6.4 14.1 7.7 9.3 4.7 5.8 17.1 6.1 10.2 10.3 11.9 21.4 20.8 9.9 9.3 11.4 43.3 16.8 13.1 25.6 9.0 33.1 6.0 21.0 14.1 10.6 19.8 20.1 5.5 9.9 8.5 21.5 14.8 15.7 9.0 4.4 4.9 6.5 5.1 23.0 23.8 25.7 4.8 29.6 7.2 16.4 7.3 7.6 14.4 3.7 17.1 12.7 13.5 12.4 9.6 11.1 17.5 15.2 1.8 16.9 6.8 8.8 13.8 10.9 29.1 30.2 25.1 33.6 30.1 25.8 22.3 22.2 24.4 24.9 24.0 28.7 11.5 6.4 3.9 17.9 14.2 10.8 11.3 9.0 19.4 30.1 10.7 7.4 13.1 12.8 4.8 22.0 18.8 32.1 12.2 5.7 29.4 8.3 1.2 4.6 6.7 12.5 7.3 12.2 41.5 6.0 14.1 11.9 9.7 4.7 4.5 13.8 21.8 34.6 11.4 67.3 36.9 7.6 2.0 6.7 9.3 2.2 21.1 4.0 10.6 24.4 8.1 46.4 10.3 24.1 23.4 3.3 9.1 26.4 13.8 10.5 20.3 61.8 6.5 31.5 26.3 15.1 12.8 14.4 17.2 13.9 14.2 23.4 9.3 11.9 8.5 9.6 ANTKMT "C16orf24, FAM173A, MGC2494" ENSG00000103254 "Adenine nucleotide translocase lysine methyltransferase" Q9BQD7 16 720581-722590 "Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 14.1;Cytotrophoblasts: 46.0;dendritic cells: 14.9;Extravillous trophoblasts: 37.4;Hofbauer cells: 88.4;Syncytiotrophoblasts: 25.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 74.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046262 Approved Approved Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA046262: AB_10963070" "unprognostic (3.94e-2)" "unprognostic (8.78e-2)" "unprognostic (1.55e-1)" "unprognostic (2.61e-1)" "unprognostic (6.54e-2)" "prognostic favorable (8.88e-4)" "unprognostic (2.11e-1)" "unprognostic (4.49e-1)" "unprognostic (9.54e-2)" "unprognostic (5.68e-2)" "unprognostic (4.02e-2)" "unprognostic (5.70e-2)" "prognostic favorable (4.24e-5)" "unprognostic (1.11e-2)" "unprognostic (1.76e-1)" "unprognostic (9.28e-2)" "unprognostic (3.60e-3)" 14.8 22.6 23.2 4.1 23.5 3.7 13.0 22.9 38.1 11.6 21.3 18.9 9.9 14.0 0.3 14.8 11.4 1.0 26.1 22.8 22.4 30.5 37.5 13.0 3.6 26.7 24.9 8.4 23.2 3.0 27.9 2.2 22.5 16.1 1.0 1.8 13.8 3.4 21.5 10.5 18.1 1.3 23.1 23.1 20.9 23.5 23.6 2.7 17.4 3.3 1.5 15.5 11.1 25.3 15.9 10.5 1.7 5.2 0.4 0.8 24.7 14.9 3.3 3.2 3.5 9.4 13.0 21.0 24.2 1.6 5.2 24.7 1.7 5.6 0.8 44.5 27.1 8.4 10.4 10.1 4.1 15.4 10.9 2.0 4.2 1.3 3.3 6.0 1.2 12.8 18.3 8.5 2.5 22.8 1.9 32.6 7.8 7.8 31.8 8.3 5.0 37.3 7.8 4.5 7.8 21.6 7.4 12.2 24.6 1.1 12.5 12.6 12.1 2.6 23.2 8.7 10.3 74.0 36.0 23.1 6.2 9.8 7.1 0.1 11.5 9.6 12.0 7.2 25.0 17.5 8.7 19.6 7.3 21.4 9.0 26.7 1.3 11.6 8.2 10.0 23.3 6.9 23.2 23.5 22.9 38.1 22.8 22.4 26.7 24.9 22.5 23.1 23.6 25.3 7.3 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.0 0.0 0.0 0.0 46.0 14.9 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 37.4 8.3 0.0 0.0 0.0 0.0 0.0 0.0 88.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 25.6 1.5 0.0 0.0 0.0 ANXA4 ANX4 ENSG00000196975 "Annexin A4" P09525 2 69644425-69827112 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 569.9;pancreas: 356.8" "Cell type enhanced" "Detected in all" "Cholangiocytes: 2344.8;Ductal cells: 1469.8;Proximal enterocytes: 657.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "EFO-21: 414.2;Hep G2: 456.9;RPTEC TERT1: 623.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005076, HPA007393, CAB017560" Enhanced Approved Cytosol NA NA 550000 "Cluster 24: B-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 1: Pancreatic cells - Digestion" Cytosol "CAB005076: AB_630869, CAB017560: AB_2227370, HPA007393: AB_1078168" "prognostic unfavorable (8.55e-4)" "unprognostic (3.37e-2)" "unprognostic (4.82e-2)" "unprognostic (9.03e-2)" "unprognostic (1.62e-3)" "unprognostic (1.66e-1)" "unprognostic (3.57e-1)" "unprognostic (3.21e-1)" "unprognostic (4.52e-2)" "prognostic unfavorable (2.38e-4)" "unprognostic (7.23e-3)" "unprognostic (1.29e-1)" "prognostic unfavorable (6.05e-4)" "unprognostic (1.79e-1)" "unprognostic (8.85e-2)" "unprognostic (3.60e-2)" "unprognostic (3.97e-2)" 48.2 21.6 14.5 33.6 15.4 30.8 45.9 14.9 18.9 62.4 52.4 101.7 271.3 50.9 30.3 43.0 68.6 569.9 26.1 14.4 15.2 104.0 120.9 81.6 21.1 15.6 15.1 38.8 356.8 78.0 11.9 52.7 15.8 46.3 92.3 30.0 39.2 52.1 17.2 61.0 232.4 52.0 15.7 24.2 108.2 9.7 15.2 23.0 43.6 20.4 24.0 61.3 50.2 16.6 69.6 249.4 3.4 31.0 185.0 158.3 11.3 66.0 101.5 27.1 38.0 37.9 121.7 22.8 414.2 109.5 78.9 104.7 23.8 108.1 27.6 65.2 20.3 35.0 20.5 456.9 131.2 12.5 43.0 95.9 104.8 36.5 87.3 62.9 71.1 11.0 2.0 20.1 74.7 63.8 18.3 22.8 6.1 280.0 34.3 19.4 6.8 28.3 623.2 99.1 5.1 22.9 72.9 99.5 103.8 35.6 33.3 156.3 100.9 49.2 23.8 65.5 37.7 8.2 9.7 1.3 75.8 59.7 34.1 80.4 34.7 29.6 23.1 42.5 17.5 40.6 11.7 17.5 50.6 46.7 2.0 12.5 4.9 9.5 58.7 15.5 14.5 24.2 14.5 15.4 14.9 18.9 14.4 15.2 15.6 15.1 15.8 15.7 15.2 16.6 66.4 205.1 154.8 47.3 27.3 74.2 98.5 148.2 68.9 8.2 36.8 36.4 10.6 2344.8 139.4 84.6 6.2 86.4 27.2 315.1 221.1 1469.8 14.6 257.9 79.0 49.1 18.6 12.6 29.9 344.4 370.1 103.6 196.7 488.8 111.5 24.3 33.9 68.5 227.6 8.4 17.7 193.8 240.1 46.1 80.4 11.2 64.7 54.5 92.5 63.7 87.2 48.7 45.3 17.6 106.0 245.7 268.6 92.2 6.9 55.6 657.1 400.4 230.2 59.9 6.6 27.6 64.6 15.8 3.7 61.3 79.6 439.6 32.5 19.1 174.1 96.9 ANXA6 ANX6 ENSG00000197043 "Annexin A6" P08133 5 151100706-151157785 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 343.8;monocytes: 445.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 861.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002462, CAB005077, HPA009650, HPA009977" Enhanced Approved Cytosol NA NA 1800000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Cytosol "CAB005077: AB_630873, HPA002462: AB_1078166, HPA009650: AB_1844867, HPA009977: " "unprognostic (1.74e-1)" "unprognostic (5.85e-2)" "unprognostic (1.03e-1)" "unprognostic (5.81e-2)" "unprognostic (2.44e-1)" "unprognostic (9.41e-2)" "unprognostic (1.17e-1)" "unprognostic (1.75e-1)" "unprognostic (9.63e-2)" "unprognostic (1.60e-2)" "unprognostic (1.08e-3)" "unprognostic (2.49e-2)" "prognostic unfavorable (1.31e-5)" "unprognostic (6.29e-2)" "unprognostic (1.74e-1)" "unprognostic (1.28e-3)" "unprognostic (1.38e-3)" 292.9 135.4 98.1 164.2 104.1 109.7 188.3 94.0 150.6 148.9 151.8 196.0 44.5 181.5 105.0 94.7 149.9 108.7 188.7 102.5 123.1 82.6 214.4 131.6 161.8 144.2 109.4 181.7 78.3 29.6 161.9 141.1 146.2 124.9 78.2 133.6 70.3 208.6 331.3 62.7 119.9 300.1 92.3 150.9 111.4 52.5 127.4 160.8 86.7 371.5 176.4 206.5 107.4 104.8 3.0 30.4 212.8 317.1 861.2 417.8 55.1 397.4 526.4 323.5 477.6 106.7 15.6 26.9 138.5 578.6 268.1 0.5 165.9 200.2 300.3 110.5 52.1 15.3 62.1 204.7 295.0 97.6 94.7 508.6 1.5 282.3 42.0 476.9 420.6 197.5 22.0 396.1 737.6 100.4 181.8 151.7 56.2 1.2 92.4 120.4 592.9 31.0 42.2 0.3 12.2 49.3 39.9 282.7 175.6 308.4 488.3 201.1 326.8 296.6 84.2 19.4 107.1 205.4 289.5 4.5 154.5 459.7 46.2 89.7 89.4 82.9 290.4 54.7 190.4 175.4 213.4 263.3 118.3 179.0 145.8 181.6 17.6 261.9 25.0 30.2 190.9 331.7 98.1 104.1 94.0 150.6 102.5 123.1 144.2 109.4 146.2 92.3 127.4 104.8 90.3 16.0 17.3 19.2 146.8 11.0 11.5 2.2 1.8 16.5 30.7 24.0 59.5 12.8 1.1 23.9 6.2 64.3 110.3 0.3 25.4 6.5 56.9 1.8 38.5 45.6 21.4 36.4 36.5 17.8 33.7 105.9 9.2 1.7 57.5 343.8 57.1 147.1 85.4 15.2 36.3 2.4 0.0 41.0 77.8 46.8 123.3 41.2 55.2 10.3 445.2 45.6 187.4 18.6 5.6 12.1 1.2 211.4 120.3 7.3 1.0 48.4 4.7 125.8 230.1 55.3 150.6 2.5 1.5 0.6 8.1 177.2 143.4 149.4 2.5 1.5 AP3D1 ADTD ENSG00000065000 "Adaptor related protein complex 3 subunit delta 1" O14617 19 2100988-2164468 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Albinism, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074408 Approved Cytosol No No 28000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA074408: AB_2686686" "unprognostic (5.30e-2)" "unprognostic (1.75e-1)" "unprognostic (1.12e-1)" "unprognostic (2.24e-3)" "unprognostic (1.37e-1)" "unprognostic (6.35e-2)" "prognostic unfavorable (9.23e-4)" "unprognostic (4.24e-2)" "unprognostic (8.05e-2)" "unprognostic (5.70e-2)" "unprognostic (6.68e-3)" "unprognostic (9.37e-2)" "prognostic favorable (2.61e-6)" "unprognostic (8.11e-3)" "unprognostic (1.22e-1)" "unprognostic (6.25e-2)" "unprognostic (1.73e-2)" 30.0 40.7 39.0 36.3 39.0 27.6 28.8 29.4 55.1 29.5 39.4 36.2 35.8 35.1 16.6 38.2 32.5 28.0 43.7 45.0 39.8 35.8 40.9 31.1 37.2 39.4 43.3 29.8 63.9 40.0 56.4 33.4 48.0 31.3 22.5 29.6 48.0 34.0 61.1 30.0 35.4 32.8 26.0 34.8 37.7 44.9 38.9 33.2 43.9 40.3 27.6 34.3 25.5 34.5 114.8 117.5 68.5 105.0 85.7 71.8 83.9 90.3 87.9 94.2 85.2 134.8 61.8 61.7 51.0 134.1 115.7 76.4 99.2 109.7 61.1 89.9 94.6 80.5 74.7 106.3 149.9 88.4 102.5 89.5 72.3 98.1 141.6 79.7 92.6 44.2 84.2 210.9 84.1 84.4 85.6 46.8 102.8 78.2 74.2 90.3 75.0 83.4 70.7 162.7 97.4 81.1 82.3 85.7 154.2 62.5 83.2 101.0 121.7 89.7 37.7 123.4 106.7 176.5 184.6 78.6 122.5 57.4 91.5 0.2 3.3 2.9 3.5 3.6 5.6 2.4 3.4 4.1 3.9 2.9 2.7 3.4 3.4 5.5 3.0 7.5 2.1 2.2 39.0 39.0 29.4 55.1 45.0 39.8 39.4 43.3 48.0 26.0 38.9 34.5 29.5 60.9 61.7 41.4 35.5 20.3 41.3 20.3 36.5 66.6 39.5 26.5 77.7 44.3 34.1 40.5 35.5 55.3 32.5 79.5 21.5 53.3 70.7 34.4 36.9 37.1 47.8 42.9 24.1 74.2 71.9 38.2 69.8 48.9 17.1 38.9 29.6 49.2 66.9 48.8 30.2 68.8 18.3 38.4 30.2 68.6 37.9 43.4 39.2 18.7 31.7 55.5 29.9 21.1 28.3 67.7 54.0 38.0 67.6 65.5 52.6 36.0 30.3 43.9 19.7 37.8 33.6 105.3 129.5 38.0 23.3 78.0 36.9 39.6 56.8 59.4 APEH "D3F15S2, D3S48E, DNF15S2" ENSG00000164062 "Acylaminoacyl-peptide hydrolase" P13798 3 49674014-49683971 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029700, HPA029701, HPA029702, HPA029703" Enhanced Enhanced Cytosol No No 2300000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA029700: AB_10599278, HPA029701: AB_10600333, HPA029702: AB_10602411, HPA029703: AB_10601348" "unprognostic (4.93e-2)" "unprognostic (5.42e-2)" "unprognostic (6.04e-3)" "unprognostic (2.71e-1)" "unprognostic (9.32e-2)" "unprognostic (8.20e-2)" "unprognostic (3.65e-2)" "unprognostic (2.48e-1)" "unprognostic (5.89e-2)" "unprognostic (8.03e-2)" "unprognostic (3.21e-1)" "unprognostic (4.30e-2)" "prognostic favorable (3.32e-10)" "unprognostic (2.11e-2)" "unprognostic (1.12e-1)" "unprognostic (4.34e-2)" "unprognostic (7.67e-2)" 21.7 43.6 18.0 30.7 18.0 42.3 26.8 17.9 22.8 24.8 27.7 48.5 48.6 19.7 24.7 40.2 33.7 22.3 40.6 17.7 19.9 65.8 63.3 26.8 35.2 19.2 21.3 24.6 34.8 63.0 38.3 31.9 24.3 31.0 51.7 12.9 34.0 29.5 103.8 32.8 35.1 28.1 16.8 27.2 35.5 18.7 20.0 37.3 48.6 103.9 43.4 35.0 21.2 16.7 101.2 79.2 84.2 110.8 71.3 48.3 113.6 64.2 79.3 87.4 91.2 130.1 101.7 127.1 70.0 71.7 78.9 89.8 95.1 143.4 64.2 61.9 41.0 138.8 123.4 105.1 72.0 145.5 204.7 55.0 106.5 49.2 101.4 85.5 78.7 86.4 86.6 59.8 86.0 90.8 105.3 76.6 50.4 140.5 75.3 38.4 72.8 165.1 169.9 226.7 40.4 71.2 72.4 166.7 78.9 61.0 112.1 77.2 36.1 53.8 93.0 83.6 86.8 69.8 54.5 77.7 91.7 104.1 78.7 57.9 43.0 52.8 44.8 47.6 34.8 33.3 36.3 41.9 43.6 27.6 37.9 37.4 13.6 39.0 47.6 35.1 50.4 51.9 18.0 18.0 17.9 22.8 17.7 19.9 19.2 21.3 24.3 16.8 20.0 16.7 5.4 41.7 25.3 7.5 20.1 8.7 23.3 50.2 11.4 6.8 20.8 15.9 46.8 30.0 39.4 27.6 12.5 83.7 16.5 83.2 43.0 44.4 6.4 16.6 13.8 9.0 26.5 43.8 4.8 34.7 64.8 16.4 41.8 20.5 23.5 20.0 13.2 74.7 51.1 8.4 4.7 47.1 63.1 35.9 11.9 10.9 15.2 23.2 21.4 2.8 26.8 30.4 27.8 3.0 2.0 39.0 35.8 13.5 39.4 18.0 85.4 80.7 19.4 11.1 13.1 10.6 25.2 33.2 28.5 30.6 9.2 62.1 23.9 28.5 74.0 23.7 AR "AIS, DHTR, HUMARA, NR3C4, SBMA, SMAX1" ENSG00000169083 "Androgen receptor" P10275 X 67544021-67730619 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 38.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 93.7;Granulosa cells: 104.8;Hepatocytes: 269.2;Leydig cells: 77.9;Peritubular cells: 86.5;Skeletal myocytes: 75.0" "Cancer enhanced" "Detected in many" "breast cancer: 15.6;prostate cancer: 16.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 13.3;BJ hTERT+: 10.3;HAP1: 14.9;LHCN-M2: 16.1;RH-30: 23.6;T-47d: 10.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000001, HPA004733, CAB065764" Enhanced Supported Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 35: Glandular cells - Unknown function" Cytosol "CAB000001: AB_2060174, CAB065764: AB_10620739, HPA004733: " "unprognostic (1.34e-1)" "unprognostic (8.10e-3)" "unprognostic (2.49e-2)" "unprognostic (5.95e-2)" "unprognostic (1.04e-2)" "unprognostic (3.35e-2)" "prognostic favorable (8.77e-4)" "unprognostic (4.99e-2)" "unprognostic (1.72e-1)" "unprognostic (7.79e-2)" "unprognostic (2.30e-1)" "unprognostic (2.29e-1)" "prognostic favorable (1.03e-8)" "unprognostic (8.23e-3)" "unprognostic (8.90e-2)" "unprognostic (4.23e-2)" "unprognostic (7.97e-2)" 6.7 1.0 1.1 0.5 1.3 0.0 8.7 1.7 1.1 23.6 0.2 2.0 0.2 18.6 16.1 1.2 20.7 2.0 5.8 1.0 3.5 3.6 38.2 1.5 0.3 3.5 2.6 14.6 0.8 0.1 1.9 0.1 2.7 16.5 0.6 0.2 1.4 18.2 13.9 5.2 0.9 9.5 2.1 1.3 1.5 3.9 4.8 2.7 2.1 6.1 0.5 3.5 12.9 2.0 0.0 4.8 13.3 0.0 0.0 0.0 0.0 7.3 10.3 0.3 0.1 0.1 0.0 0.0 0.0 1.0 0.0 0.0 14.9 0.0 0.0 0.0 2.4 0.0 1.5 0.0 0.8 0.0 0.0 5.5 0.0 1.8 0.0 0.0 3.9 0.1 4.6 2.2 16.1 1.5 0.0 0.0 5.4 0.0 0.0 0.0 23.6 0.1 0.4 0.0 0.0 0.0 0.0 0.3 0.0 3.6 10.9 7.6 0.3 0.3 2.2 0.0 3.5 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.3 1.7 1.1 1.0 3.5 3.5 2.6 2.7 2.1 4.8 2.0 3.1 0.0 5.0 28.4 0.4 9.7 17.8 0.2 15.9 0.7 93.7 33.7 37.4 14.3 10.7 3.7 0.0 3.5 14.0 0.0 1.9 11.3 1.1 2.9 49.1 10.5 0.0 5.3 7.7 0.0 0.2 39.4 0.0 5.8 1.3 104.8 36.0 269.2 0.8 0.0 17.8 0.3 0.0 2.2 4.2 4.4 77.9 3.3 10.6 1.0 1.7 0.2 0.0 26.7 0.2 0.6 0.0 86.5 0.0 36.5 0.6 27.7 3.6 0.3 65.7 75.0 20.8 0.8 3.3 12.7 16.1 1.0 1.7 37.8 0.2 22.0 ARF6 ENSG00000165527 "ADP ribosylation factor 6" P62330 14 49893082-49897054 "Predicted intracellular proteins, RAS pathway related proteins" "Cell cycle, Cell division, Differentiation, Neurogenesis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 716.1;Suprabasal keratinocytes: 673.3;Urothelial cells: 703.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002778, CAB079914" Approved Supported Cytosol NA NA 310000 "Cluster 44: Non-specific - Transcription" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB002778: , CAB079914: AB_2539861" "unprognostic (1.21e-1)" "unprognostic (2.75e-3)" "unprognostic (1.80e-1)" "unprognostic (7.02e-2)" "unprognostic (2.85e-1)" "unprognostic (1.83e-1)" "unprognostic (4.12e-3)" "unprognostic (2.16e-1)" "unprognostic (1.23e-1)" "unprognostic (1.41e-1)" "prognostic unfavorable (3.10e-5)" "unprognostic (1.61e-1)" "unprognostic (1.67e-1)" "unprognostic (8.37e-3)" "unprognostic (1.22e-1)" "unprognostic (2.37e-1)" "unprognostic (1.49e-2)" 32.1 25.3 13.4 43.6 14.2 83.1 32.6 15.2 15.3 35.7 16.3 53.4 46.4 21.7 26.6 108.2 28.3 32.8 18.3 11.8 14.3 29.7 46.1 31.5 62.0 14.7 14.3 15.3 24.7 20.4 12.6 36.3 15.4 32.2 51.0 13.2 36.3 19.2 26.1 66.0 51.2 23.8 15.6 49.6 46.7 15.8 15.9 45.2 21.1 17.1 66.7 46.8 55.7 15.6 141.5 58.2 38.4 44.8 51.5 68.4 78.3 86.5 62.6 60.3 62.2 42.6 96.2 91.3 43.7 72.7 46.3 101.7 43.7 69.3 71.3 181.4 34.9 47.2 30.6 38.3 58.1 87.2 60.7 53.7 81.5 48.9 93.7 72.1 67.6 58.3 45.9 176.9 84.7 101.5 77.7 76.5 42.0 75.9 82.8 59.4 50.1 53.9 157.6 112.9 56.4 37.4 68.9 102.3 89.0 46.5 78.0 70.0 90.0 111.9 57.4 66.7 66.1 94.3 104.4 68.6 40.1 50.9 81.3 34.2 20.7 21.1 34.7 33.0 37.6 33.5 33.7 35.3 23.9 26.6 23.0 29.6 14.7 29.1 31.4 15.8 36.2 23.4 13.4 14.2 15.2 15.3 11.8 14.3 14.7 14.3 15.4 15.6 15.9 15.6 102.9 51.3 29.9 2.9 233.7 599.8 529.1 47.9 231.6 22.9 154.4 80.1 18.5 127.2 47.6 101.2 2.1 152.7 298.8 276.0 158.5 125.4 5.8 95.6 98.5 117.1 99.3 140.1 5.3 80.0 208.1 94.9 115.7 143.7 79.9 40.3 108.5 143.3 168.0 33.7 5.9 167.0 20.3 195.6 716.1 8.3 33.5 184.5 304.1 15.0 204.9 42.2 192.6 6.0 8.9 130.4 161.6 32.7 182.4 443.4 190.8 166.5 30.3 21.6 46.0 68.8 90.7 62.7 48.7 361.4 673.3 202.9 311.0 52.6 182.5 703.8 ARHGAP26 "GRAF, KIAA0621, OPHN1L, OPHN1L1" ENSG00000145819 "Rho GTPase activating protein 26" Q9UNA1 5 142770377-143229011 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 237.3;Excitatory neurons: 611.6;Inhibitory neurons: 261.5;Late spermatids: 153.3;Microglial cells: 326.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "neutrophil: 24.7;NK-cell: 9.8" "Group enriched" "Detected in many" 4 "granulocytes: 24.7;NK-cells: 9.8" "Cell line enhanced" "Detected in many" "Karpas-707: 85.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035106, HPA035107" Enhanced Approved Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA035106: AB_2674465, HPA035107: AB_10669855" "prognostic favorable (2.05e-4)" "prognostic favorable (1.36e-4)" "prognostic favorable (6.95e-4)" "prognostic favorable (5.93e-6)" "unprognostic (1.19e-1)" "unprognostic (1.93e-2)" "unprognostic (4.19e-3)" "unprognostic (5.93e-2)" "unprognostic (2.22e-1)" "unprognostic (9.43e-3)" "unprognostic (7.19e-3)" "unprognostic (8.65e-2)" "unprognostic (3.21e-3)" "unprognostic (5.67e-2)" "unprognostic (2.70e-2)" "unprognostic (2.95e-2)" "prognostic favorable (2.88e-6)" 11.0 4.5 10.9 17.7 6.5 36.4 11.3 19.3 17.0 11.9 0.6 12.9 12.0 7.7 9.1 6.4 15.5 14.2 15.0 10.8 3.4 8.9 6.8 19.0 6.4 0.5 2.7 3.0 4.9 3.9 12.2 20.9 0.3 7.4 12.7 17.2 12.8 4.2 12.6 7.4 11.3 9.7 2.3 16.7 15.2 15.4 10.1 13.8 8.3 10.5 12.2 12.2 5.8 9.9 16.4 29.1 8.0 7.6 12.3 12.7 12.4 2.2 2.4 7.6 12.1 44.9 33.0 2.0 16.1 4.9 21.5 7.5 4.1 15.3 8.7 33.8 4.6 0.1 5.3 26.9 7.8 22.6 2.9 4.7 23.0 12.8 31.0 5.6 10.2 9.9 0.6 85.4 2.4 2.3 12.9 9.2 4.3 23.2 7.7 5.2 12.5 36.5 20.4 25.6 3.4 4.7 3.8 4.4 7.1 6.5 2.4 6.2 21.0 4.1 5.8 0.4 8.1 4.0 14.0 0.4 10.7 21.3 5.6 4.0 3.9 2.3 3.8 2.5 1.7 0.5 0.8 2.4 3.0 0.4 0.3 1.1 24.7 9.8 1.6 0.7 0.3 1.8 10.9 6.5 19.3 17.0 10.8 3.4 0.5 2.7 0.3 2.3 10.1 9.9 39.4 16.0 22.5 237.3 5.8 6.9 13.8 13.2 5.7 15.9 20.7 17.0 37.6 21.5 14.1 0.0 8.4 1.3 41.6 38.7 0.0 17.9 77.2 17.9 4.0 32.5 3.6 11.8 611.6 21.1 0.6 13.6 39.8 55.6 26.6 6.4 40.0 6.5 26.4 75.7 261.5 26.4 0.0 48.0 44.9 153.3 6.5 51.6 10.6 326.0 47.3 7.5 40.2 30.7 29.8 21.1 27.8 14.3 14.5 29.3 27.9 5.8 16.1 52.6 46.0 27.6 17.7 2.6 8.7 7.5 5.5 1.9 29.3 50.5 26.8 36.2 ARHGAP4 "C1, KIAA0131, p115, RhoGAP4, SrGAP4" ENSG00000089820 "Rho GTPase activating protein 4" P98171 X 153907367-153934999 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 119.1;lymphoid tissue: 120.9" "Cell type enhanced" "Detected in many" "B-cells: 65.3;dendritic cells: 70.0;Hofbauer cells: 86.6;Kupffer cells: 77.2;Macrophages: 76.0;NK-cells: 70.0;T-cells: 69.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 103.0;HL-60: 76.7;Karpas-707: 90.8;MOLT-4: 93.0;RPMI-8226: 180.7;THP-1: 83.7;U-698: 90.4;U-937: 79.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA000301, HPA001012, HPA001083" Enhanced Supported Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 57: B-cells - Immune response" Cytosol "HPA000301: , HPA001012: AB_1078201, HPA001083: AB_1078199" "unprognostic (3.54e-2)" "prognostic favorable (3.94e-5)" "prognostic unfavorable (1.97e-5)" "unprognostic (5.79e-2)" "unprognostic (9.42e-2)" "prognostic favorable (3.31e-4)" "unprognostic (5.72e-3)" "unprognostic (1.39e-1)" "unprognostic (3.27e-1)" "unprognostic (1.37e-1)" "unprognostic (7.81e-3)" "unprognostic (1.45e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (8.47e-3)" "unprognostic (2.01e-1)" "unprognostic (1.03e-1)" "unprognostic (1.99e-1)" 20.0 12.5 5.2 52.2 5.4 119.1 13.4 6.9 6.5 9.9 15.0 18.6 14.2 9.7 3.1 7.0 12.9 14.4 10.3 5.7 6.3 22.6 8.6 36.2 73.8 10.9 8.3 5.4 5.9 1.7 8.6 21.2 9.3 11.1 6.9 1.2 9.2 3.8 4.3 5.0 49.7 6.5 8.2 120.9 12.6 7.2 8.5 42.7 10.9 1.5 33.7 11.6 9.2 10.0 1.5 0.6 1.0 5.9 0.2 0.0 2.5 1.0 0.4 0.1 0.2 0.4 42.8 103.0 5.9 0.1 0.8 1.2 4.6 0.2 0.0 27.8 3.4 44.4 0.5 1.7 3.6 76.7 59.7 0.2 0.4 0.0 0.3 0.5 9.1 22.4 0.5 90.8 0.5 4.6 93.0 1.5 3.7 0.4 0.3 44.6 12.0 180.7 0.4 0.7 8.4 12.1 0.9 2.1 0.9 1.2 19.0 83.7 1.9 0.3 1.3 0.9 0.5 60.1 55.8 90.4 0.7 79.9 0.2 10.9 26.1 35.4 26.2 42.4 18.6 18.0 18.8 21.1 25.5 16.9 17.4 17.4 22.4 16.0 59.4 31.6 23.5 26.1 5.2 5.4 6.9 6.5 5.7 6.3 10.9 8.3 9.3 8.2 8.5 10.0 16.0 9.6 22.7 2.6 65.3 3.4 0.6 0.2 0.0 13.7 2.4 6.1 48.3 1.5 2.7 18.4 4.2 1.9 70.0 9.5 5.9 0.9 0.1 2.4 1.4 13.0 4.8 11.3 2.1 0.6 1.9 3.5 7.1 1.5 34.2 7.7 4.2 0.5 86.6 3.3 1.4 6.6 0.0 77.2 31.5 0.2 0.9 76.0 10.6 19.7 42.5 1.9 70.0 2.0 0.7 0.2 0.5 0.0 32.9 0.5 3.0 0.8 8.7 4.6 0.0 7.1 2.6 0.7 5.2 1.6 1.7 1.4 69.5 1.1 5.0 0.4 ARHGAP6 rhoGAPX-1 ENSG00000047648 "Rho GTPase activating protein 6" O43182 X 11117651-11665920 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 44.3;Microglial cells: 127.4;Oligodendrocyte precursor cells: 60.3;Prostatic glandular cells: 54.4;Sertoli cells: 46.0;Skeletal myocytes: 62.3;Smooth muscle cells: 44.4" "Cancer enhanced" "Detected in many" "prostate cancer: 12.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 26.2;ASC TERT1: 34.2;HEL: 36.4;HMC-1: 24.7;HSkMC: 33.8;K-562: 26.5;RT4: 20.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001798, HPA036779, HPA064390" Enhanced Supported Cytosol "Intracellular and membrane" NA NA 350000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA001798: , HPA036779: AB_10672229, HPA064390: AB_2685253" "unprognostic (2.36e-1)" "unprognostic (1.68e-2)" "unprognostic (3.49e-2)" "unprognostic (7.31e-2)" "unprognostic (6.34e-2)" "unprognostic (1.69e-2)" "unprognostic (4.70e-2)" "unprognostic (2.79e-1)" "unprognostic (1.70e-1)" "unprognostic (7.46e-4)" "unprognostic (1.53e-1)" "unprognostic (1.59e-1)" "prognostic favorable (1.55e-8)" "unprognostic (1.60e-2)" "unprognostic (5.96e-2)" "unprognostic (1.28e-2)" "unprognostic (7.99e-4)" 10.8 1.1 9.0 1.7 5.1 0.7 5.6 2.0 4.2 7.6 3.2 13.9 2.1 10.5 8.2 3.8 8.4 4.2 4.0 5.0 5.8 6.5 0.9 9.6 1.2 3.2 4.0 16.4 1.9 1.2 3.2 7.0 3.2 27.6 3.9 1.0 2.6 30.9 9.6 2.5 4.7 12.9 2.6 5.9 4.1 1.9 6.1 1.0 25.4 8.1 0.8 10.4 5.7 3.8 0.0 0.0 2.4 0.0 26.2 34.2 0.6 0.4 0.6 1.4 0.9 0.4 0.0 0.0 0.0 5.0 0.0 0.1 0.9 0.0 1.2 0.6 0.5 36.4 0.4 0.0 9.7 0.1 24.7 33.8 0.0 2.5 0.1 3.1 0.7 0.1 26.5 12.3 1.5 0.0 0.0 0.2 0.7 0.2 0.4 0.1 11.6 15.7 8.3 20.3 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.4 0.3 1.6 0.7 7.1 0.2 0.7 0.0 0.0 0.5 0.2 4.0 0.2 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.5 9.0 5.1 2.0 4.2 5.0 5.8 3.2 4.0 3.2 2.6 6.1 3.8 9.6 0.0 1.7 10.4 5.3 2.0 16.9 0.3 2.8 4.3 2.3 3.3 4.7 0.0 2.6 33.1 0.0 0.6 0.4 0.0 25.4 0.0 0.1 0.1 5.1 9.2 1.2 2.1 5.5 1.1 0.7 29.1 3.6 0.2 40.0 3.0 8.2 0.0 4.9 0.0 44.3 0.4 0.0 2.2 18.9 0.9 16.1 29.1 5.4 127.4 3.4 7.2 0.0 60.3 3.5 0.7 0.0 10.1 4.9 54.4 0.0 7.4 5.6 0.7 46.0 62.3 44.4 0.2 0.4 4.5 1.7 0.0 1.2 2.1 0.0 22.3 ARHGDIA "GDIA1, RHOGDI" ENSG00000141522 "Rho GDP dissociation inhibitor alpha" P52565 17 81867721-81871378 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010005, HPA021407" Approved Supported Cytosol NA NA 21000000 "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "CAB010005: AB_2227516, HPA021407: AB_1856267" "unprognostic (1.08e-1)" "unprognostic (2.29e-2)" "unprognostic (1.13e-1)" "unprognostic (3.05e-2)" "unprognostic (5.00e-2)" "unprognostic (8.39e-3)" "unprognostic (1.39e-2)" "prognostic unfavorable (7.63e-4)" "unprognostic (5.32e-2)" "unprognostic (4.67e-2)" "unprognostic (2.67e-2)" "unprognostic (6.62e-2)" "unprognostic (1.82e-1)" "unprognostic (1.34e-1)" "unprognostic (1.76e-1)" "unprognostic (3.29e-1)" "unprognostic (6.88e-3)" 274.5 196.2 116.6 154.7 122.9 219.4 227.6 92.6 173.4 215.5 64.6 215.7 177.7 222.0 23.8 265.1 191.2 64.3 181.1 122.2 141.1 236.2 220.7 266.1 116.9 136.3 148.9 174.8 195.2 69.6 187.3 101.9 158.2 206.0 52.9 14.6 180.0 78.7 131.9 198.6 225.6 72.4 105.0 243.9 194.3 92.0 131.4 83.4 173.4 32.8 66.9 203.4 212.2 112.9 472.6 455.1 146.6 233.1 131.8 162.9 167.2 396.0 251.3 292.1 216.0 229.0 173.7 249.4 164.9 299.8 254.9 252.3 160.3 302.6 120.7 192.3 422.2 266.3 267.7 303.0 270.6 418.3 367.4 211.1 137.0 213.5 180.5 147.7 450.1 204.1 221.5 334.8 235.8 285.4 611.3 432.9 173.0 159.8 405.3 274.2 185.4 200.6 193.7 289.5 193.0 568.8 208.5 522.2 386.9 105.3 247.5 335.7 499.7 575.1 494.2 539.3 681.4 292.8 164.9 256.5 497.7 249.9 399.8 39.5 47.9 87.5 64.3 72.5 60.8 35.8 53.6 62.5 47.9 27.4 34.5 42.1 30.2 45.2 101.9 55.3 55.4 60.4 116.6 122.9 92.6 173.4 122.2 141.1 136.3 148.9 158.2 105.0 131.4 112.9 146.0 38.5 59.1 14.0 152.2 127.2 201.5 173.0 63.2 18.3 78.8 65.4 2.9 62.9 86.7 79.1 10.4 130.1 164.6 289.7 135.0 234.2 8.3 66.4 97.5 134.6 134.6 34.9 13.9 265.0 263.4 98.2 120.8 124.1 118.6 76.4 112.1 82.7 243.2 52.2 10.4 173.7 101.7 167.1 157.8 19.5 86.6 167.4 193.9 15.0 243.9 82.6 187.4 9.5 17.5 424.5 286.3 74.1 171.3 183.5 300.7 157.5 46.0 11.9 118.3 70.6 121.4 38.9 44.1 88.5 116.1 221.9 169.3 78.6 156.2 222.2 ARHGDIB "GDIA2, GDID4, Ly-GDI, RAP1GN1, RhoGDI2" ENSG00000111348 "Rho GDP dissociation inhibitor beta" P52566 12 14942031-14961728 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 1579.9;lymphoid tissue: 1075.8" "Cell type enhanced" "Detected in many" "dendritic cells: 703.8;Extravillous trophoblasts: 667.6;granulocytes: 700.2;Hofbauer cells: 915.2;Kupffer cells: 742.6;Macrophages: 672.9;NK-cells: 999.0;T-cells: 895.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 1636.5;HL-60: 1927.3;HMC-1: 2070.0;JURKAT: 1421.7;MOLT-4: 2313.6;REH: 1912.5;U-698: 1750.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018584, HPA051235" Enhanced Supported Cytosol NA NA 61000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "CAB018584: AB_647972, HPA051235: AB_2681398" "unprognostic (2.29e-3)" "unprognostic (8.10e-2)" "unprognostic (2.09e-1)" "unprognostic (1.39e-2)" "unprognostic (9.16e-2)" "unprognostic (1.90e-2)" "unprognostic (2.44e-1)" "unprognostic (1.47e-2)" "unprognostic (3.46e-1)" "unprognostic (2.47e-2)" "unprognostic (2.19e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (1.74e-1)" "unprognostic (4.42e-3)" "unprognostic (4.97e-2)" "prognostic favorable (3.42e-4)" 188.8 74.1 48.7 521.0 51.2 1579.9 170.4 56.0 77.6 85.4 57.9 112.9 79.6 68.0 48.4 82.9 85.3 165.9 110.7 49.4 56.4 95.9 139.0 280.3 905.3 68.5 65.4 27.6 32.2 54.1 35.4 143.8 68.4 68.8 142.4 5.3 122.3 66.3 56.3 74.2 201.6 144.3 61.8 592.6 108.1 19.5 65.6 1075.8 110.6 79.0 1036.8 290.4 67.4 79.6 147.8 5.5 5.8 327.3 23.7 17.6 2.1 6.0 1.8 2.3 1.6 19.3 156.9 1210.9 74.3 28.0 1.9 171.1 0.0 270.8 17.9 2.3 0.0 1636.5 3.5 0.7 5.2 1927.3 2070.0 2.5 37.5 0.8 24.2 5.6 929.0 1421.7 8.7 454.5 28.8 0.8 2313.6 1382.4 7.1 3.3 1.7 1912.5 21.3 540.3 52.7 845.5 1.3 1.4 1.8 205.7 2.5 14.1 10.9 1385.1 1171.8 4.6 11.5 2.2 36.2 74.5 13.0 1750.9 5.3 1339.7 2.4 5890.8 2659.3 6464.2 2731.2 3085.1 2695.1 2676.3 3099.3 3090.3 2210.1 2532.9 2986.0 3120.5 5422.5 2408.4 3802.9 955.6 5589.7 9860.2 48.7 51.2 56.0 77.6 49.4 56.4 68.5 65.4 68.4 61.8 65.6 79.6 189.6 60.9 143.0 0.7 575.2 68.2 51.9 11.1 5.7 0.6 99.7 64.5 14.0 11.5 79.5 58.8 0.0 89.6 703.8 5.3 17.6 21.9 1.5 3.2 6.1 175.6 1.2 182.1 0.7 342.7 667.6 47.3 42.3 3.6 700.2 0.4 342.3 11.1 915.2 0.0 0.2 2.2 8.2 742.6 487.7 4.1 53.4 672.9 90.7 26.2 451.3 3.3 999.0 0.5 0.1 53.5 16.3 58.6 292.5 6.9 0.2 9.2 39.0 1.2 243.3 10.3 187.9 1.2 2.3 5.5 56.1 68.0 895.2 14.9 6.7 94.7 ARHGEF17 "KIAA0337, p164-RhoGEF, TEM4" ENSG00000110237 "Rho guanine nucleotide exchange factor 17" Q96PE2 11 73308276-73369388 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 38.5;Endometrial stromal cells: 40.5;Sertoli cells: 85.5;Smooth muscle cells: 67.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007991 Uncertain Approved Cytosol NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA007991: AB_1845005" "unprognostic (2.36e-1)" "unprognostic (4.33e-2)" "prognostic unfavorable (8.27e-5)" "unprognostic (6.96e-2)" "unprognostic (1.57e-1)" "unprognostic (1.39e-1)" "unprognostic (1.17e-1)" "unprognostic (1.91e-1)" "unprognostic (1.69e-1)" "unprognostic (1.46e-3)" "unprognostic (1.15e-2)" "unprognostic (2.39e-1)" "unprognostic (1.47e-1)" "unprognostic (7.54e-3)" "unprognostic (7.12e-3)" "unprognostic (6.85e-3)" "unprognostic (3.42e-3)" 32.8 12.2 32.7 9.1 39.5 3.3 24.1 24.1 45.7 37.0 15.3 38.2 5.5 39.9 15.2 10.0 30.5 17.6 34.5 29.6 33.7 24.9 5.4 31.2 5.9 38.2 31.6 24.2 8.2 19.1 15.3 23.6 37.6 25.4 5.3 7.2 11.7 27.3 11.5 10.7 16.4 22.6 21.3 12.8 19.8 7.1 36.9 3.1 36.0 12.2 2.7 26.9 20.2 28.8 9.6 11.4 24.1 28.4 18.7 15.7 14.8 26.6 38.2 25.9 16.5 30.2 8.2 0.0 18.2 50.7 11.8 14.5 8.1 10.8 10.8 16.9 2.4 0.0 21.0 11.9 21.6 0.8 0.5 27.1 12.2 15.6 9.3 16.9 19.4 1.2 0.9 0.2 14.6 13.7 0.3 17.4 3.2 6.4 2.4 4.0 27.3 0.6 16.5 6.7 15.8 12.1 22.6 26.4 31.3 22.0 43.8 8.2 12.9 12.5 25.5 5.3 8.6 1.6 0.3 0.1 4.4 1.9 19.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 32.7 39.5 24.1 45.7 29.6 33.7 38.2 31.6 37.6 21.3 36.9 28.8 13.9 16.0 16.3 38.5 0.2 3.4 2.4 6.0 5.7 12.6 11.1 12.3 25.5 8.6 7.4 7.3 0.0 7.2 0.1 1.5 0.0 6.4 1.1 10.5 40.5 10.9 1.2 1.3 29.5 0.7 5.3 10.7 2.6 8.9 0.0 13.7 10.8 0.6 2.0 23.5 24.8 0.7 0.0 0.3 4.2 2.0 10.8 1.4 1.8 8.4 1.1 11.1 0.0 10.6 2.0 2.4 0.4 20.3 1.6 4.1 0.0 4.3 5.4 2.3 85.5 5.2 67.5 1.6 8.3 1.1 2.7 6.2 0.6 2.0 1.0 1.5 ARHGEF18 "KIAA0521, MGC15913, P114-RhoGEF, p114RhoGEF" ENSG00000104880 "Rho/Rac guanine nucleotide exchange factor 18" Q6ZSZ5 19 7348937-7472485 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 17.0;Excitatory neurons: 22.2;Inhibitory neurons: 18.0;Microglial cells: 14.0;Oligodendrocyte precursor cells: 18.1;Oligodendrocytes: 30.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042689, HPA049151, HPA071867" Approved Enhanced Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA042689: AB_10794385, HPA049151: AB_2680654, HPA071867: AB_2686466" "unprognostic (2.55e-1)" "unprognostic (1.31e-2)" "unprognostic (1.57e-1)" "unprognostic (6.01e-2)" "unprognostic (1.65e-2)" "prognostic favorable (4.21e-4)" "unprognostic (1.13e-1)" "unprognostic (1.52e-3)" "unprognostic (3.56e-1)" "unprognostic (2.36e-1)" "unprognostic (1.40e-1)" "unprognostic (8.26e-2)" "prognostic favorable (3.11e-5)" "unprognostic (1.08e-1)" "unprognostic (2.21e-1)" "unprognostic (1.42e-1)" "unprognostic (3.79e-3)" 8.2 15.9 10.4 20.0 13.3 27.1 8.1 9.7 12.1 12.2 7.0 22.1 13.3 16.8 3.1 19.9 9.7 10.7 7.1 9.8 8.8 24.1 13.1 14.6 29.8 12.1 13.0 10.1 21.0 11.2 15.8 7.8 10.8 14.2 7.7 5.0 11.0 7.3 5.3 13.8 31.1 13.9 9.5 35.9 22.6 8.9 12.2 33.1 10.8 3.0 17.5 14.0 12.1 15.3 31.2 17.9 10.2 13.9 9.4 7.8 30.8 13.4 12.9 20.5 20.8 24.5 17.4 62.9 29.4 15.2 15.3 24.6 12.7 29.7 11.8 37.6 16.1 15.5 11.7 16.4 22.1 31.2 30.4 12.8 20.2 19.7 16.3 10.1 11.2 20.2 13.4 14.7 21.3 11.0 36.0 26.8 16.0 16.9 29.2 42.2 17.6 17.2 9.0 34.6 9.8 13.7 16.4 16.1 18.8 9.6 17.4 36.4 21.9 16.8 20.1 25.9 17.2 35.6 23.2 40.2 16.7 27.5 15.1 6.4 3.7 23.0 3.9 4.5 4.0 8.8 5.3 4.3 2.3 12.4 5.4 4.1 12.5 0.9 6.9 2.8 3.9 3.5 10.4 13.3 9.7 12.1 9.8 8.8 12.1 13.0 10.8 9.5 12.2 15.3 0.2 0.0 1.1 17.0 2.2 2.9 0.0 6.5 2.8 0.2 0.4 0.1 0.2 0.0 4.3 0.0 4.2 0.1 0.3 0.5 0.0 0.3 0.1 2.4 0.8 0.5 1.8 3.0 22.2 0.4 0.1 1.1 6.1 2.9 0.0 0.5 0.0 0.0 0.2 0.0 18.0 0.0 4.1 0.3 2.1 0.1 0.0 1.6 1.8 14.0 0.7 0.0 0.0 18.1 30.5 0.6 2.3 0.0 4.3 0.0 0.7 0.1 9.3 0.4 0.0 0.1 1.2 0.0 0.0 3.9 3.8 0.0 1.6 0.0 0.0 0.3 ARHGEF3 "DKFZP434F2429, GEF3, STA3, XPLN" ENSG00000163947 "Rho guanine nucleotide exchange factor 3" Q9NR81 3 56727418-57079329 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 157.8;NK-cells: 137.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 88.8;RPMI-8226: 92.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034715, HPA064945" Uncertain Approved Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 34: Non-specific - Transcription" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA034715: AB_10600780, HPA064945: AB_2685389" "unprognostic (1.84e-2)" "unprognostic (2.22e-2)" "unprognostic (1.62e-2)" "prognostic favorable (2.17e-4)" "unprognostic (8.25e-2)" "prognostic favorable (2.61e-4)" "unprognostic (9.42e-2)" "unprognostic (3.83e-2)" "unprognostic (9.67e-2)" "unprognostic (7.44e-2)" "unprognostic (6.90e-2)" "unprognostic (4.99e-2)" "prognostic favorable (1.96e-7)" "unprognostic (8.24e-2)" "unprognostic (1.92e-1)" "unprognostic (1.81e-2)" "unprognostic (3.84e-2)" 16.8 43.2 11.2 20.6 14.8 9.8 13.8 14.4 17.4 16.0 30.9 14.3 6.4 38.0 12.5 19.0 23.2 22.3 12.7 25.9 10.8 25.3 5.2 24.8 29.3 11.2 9.1 20.6 29.1 52.3 21.6 21.3 10.7 14.8 13.5 8.2 21.5 15.3 8.0 12.6 9.6 34.5 7.6 21.5 15.8 14.3 11.6 36.1 14.2 8.5 28.7 17.2 11.6 12.8 24.2 8.4 1.2 7.7 2.7 2.2 16.5 2.6 2.2 2.6 3.4 4.1 22.3 12.6 2.5 4.7 25.3 12.1 7.2 30.8 3.0 18.4 3.5 10.3 5.2 88.8 6.6 0.0 10.9 9.7 19.9 2.3 3.5 23.6 25.5 13.3 2.9 27.2 5.9 3.7 34.8 1.3 2.3 19.5 12.9 0.2 9.2 92.2 19.8 13.2 1.4 3.8 15.3 11.2 6.9 8.5 2.9 10.6 11.8 1.3 6.0 5.4 4.0 35.0 14.2 45.1 21.7 12.2 10.9 20.6 23.0 3.7 96.1 25.5 72.5 26.0 73.6 85.0 13.9 16.9 59.3 73.5 8.3 39.7 32.2 5.9 67.4 76.0 11.2 14.8 14.4 17.4 25.9 10.8 11.2 9.1 10.7 7.6 11.6 12.8 22.7 16.0 22.4 30.0 24.2 11.1 8.6 16.3 32.5 9.5 7.6 9.9 9.8 2.8 12.6 23.9 4.2 11.4 57.5 4.8 11.7 11.0 22.6 10.1 7.0 40.3 9.6 14.1 157.8 10.2 7.9 13.5 36.2 16.5 13.9 4.8 22.9 0.1 7.6 0.0 70.8 1.3 2.0 38.1 8.2 14.1 17.7 18.7 10.6 63.7 19.9 9.0 137.0 68.3 80.0 7.5 1.4 24.0 22.1 11.2 0.2 7.3 9.5 1.2 0.0 8.0 4.4 3.3 2.6 37.9 14.9 11.9 64.3 3.2 3.2 13.4 ARHGEF37 FLJ41603 ENSG00000183111 "Rho guanine nucleotide exchange factor 37" A1IGU5 5 149551947-149634968 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Muller glia cells: 36.8;Oligodendrocytes: 62.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "basophil: 9.3;neutrophil: 3.0" "Lineage enriched" "Detected in single" 12 "granulocytes: 9.3" "Cell line enhanced" "Detected in many" "EFO-21: 13.9;HaCaT: 26.1;hTCEpi: 33.8" "Region enhanced" "Detected in many" "cerebellum: 10.4" "Low region specificity" "Detected in all" "HPA043885, HPA053487" Uncertain Approved Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 35: Glandular cells - Unknown function" Cytosol "HPA043885: AB_2678715, HPA053487: AB_2682167" "unprognostic (3.51e-2)" "unprognostic (1.58e-1)" "unprognostic (2.24e-1)" "unprognostic (3.92e-1)" "unprognostic (1.17e-1)" "unprognostic (6.87e-2)" "unprognostic (1.54e-3)" "unprognostic (1.54e-1)" "unprognostic (2.64e-1)" "unprognostic (6.93e-2)" "unprognostic (2.13e-3)" "unprognostic (1.16e-2)" "prognostic favorable (6.85e-4)" "unprognostic (4.41e-2)" "unprognostic (2.12e-1)" "unprognostic (1.50e-2)" "unprognostic (2.10e-1)" 4.2 3.8 26.9 2.2 38.9 5.2 24.5 33.3 33.8 5.5 34.0 20.8 6.8 7.4 13.6 14.0 10.6 6.3 12.1 23.4 28.6 9.1 2.5 6.4 1.5 41.1 35.9 3.8 10.7 28.1 6.7 3.2 39.5 23.3 7.5 14.4 39.9 35.4 20.4 45.1 7.4 10.2 32.5 1.4 23.3 5.5 35.3 1.6 2.9 10.5 4.8 10.6 8.9 51.3 4.4 1.7 1.2 5.1 0.3 0.6 3.0 0.5 0.9 0.8 0.8 0.0 5.6 0.6 13.9 0.6 1.5 26.1 0.4 2.6 1.6 1.1 1.3 0.4 2.9 0.3 1.0 0.0 0.8 0.7 33.8 2.6 3.3 2.7 4.2 1.8 0.6 1.1 0.0 0.6 0.8 0.8 0.3 10.7 3.1 0.5 0.6 0.0 5.7 2.1 2.1 5.0 3.2 0.3 0.5 0.6 7.7 0.1 3.4 0.3 0.9 0.1 0.7 0.7 1.6 0.5 1.0 0.1 3.6 9.3 0.5 0.3 0.2 0.8 0.3 0.1 0.1 0.2 0.2 0.4 0.5 0.4 3.0 0.2 0.3 0.7 0.1 0.0 26.9 38.9 33.3 33.8 23.4 28.6 41.1 35.9 39.5 32.5 35.3 51.3 9.2 0.0 4.5 5.9 2.8 6.8 9.6 10.4 0.6 4.6 32.7 24.4 15.8 17.2 16.5 9.2 4.2 6.2 4.6 18.2 0.0 3.7 5.3 9.4 2.0 7.4 11.4 14.3 5.1 4.9 1.4 2.7 9.7 9.9 7.0 1.7 6.8 3.2 3.1 5.0 7.5 9.6 8.2 2.5 3.3 1.5 1.8 2.9 3.6 12.2 3.9 36.8 7.2 2.0 62.3 5.1 10.1 10.5 2.0 10.5 15.9 1.4 17.8 7.6 6.6 5.7 4.5 16.0 5.7 4.8 9.7 4.5 3.3 1.5 10.5 5.7 ARHGEF6 "alpha-PIX, alphaPIX, αPix, Cool-2, Cool2, KIAA0006, MRX46" ENSG00000129675 "Rac/Cdc42 guanine nucleotide exchange factor 6" Q15052 X 136665547-136780932 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 193.9;Granulosa cells: 128.2;Microglial cells: 77.8" "Cancer enhanced" "Detected in all" "glioma: 24.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 117.6;HL-60: 153.7;HMC-1: 532.0;JURKAT: 152.7;U-937: 158.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003578 Approved Approved Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA003578: AB_1078203" "unprognostic (9.64e-2)" "unprognostic (3.47e-2)" "unprognostic (3.32e-2)" "unprognostic (1.29e-2)" "unprognostic (7.28e-2)" "unprognostic (2.06e-3)" "unprognostic (9.08e-2)" "unprognostic (7.87e-3)" "unprognostic (4.21e-1)" "unprognostic (2.56e-1)" "unprognostic (1.15e-1)" "unprognostic (1.10e-1)" "unprognostic (4.69e-3)" "unprognostic (5.29e-2)" "unprognostic (1.35e-2)" "unprognostic (2.64e-1)" "unprognostic (1.28e-3)" 44.0 16.2 23.4 30.5 24.4 31.4 23.5 25.0 19.5 10.7 11.6 13.2 7.5 12.9 5.3 7.6 7.0 17.3 32.9 25.2 26.9 6.7 8.5 25.6 41.8 26.8 29.2 16.5 3.9 10.3 6.2 46.9 27.8 7.8 11.1 4.6 8.7 8.8 68.7 6.2 14.4 16.6 29.0 39.4 12.3 3.8 26.5 51.4 5.6 54.7 39.6 14.3 8.7 30.1 1.1 0.0 5.1 0.0 11.2 28.5 0.1 1.6 9.5 1.5 8.2 0.0 0.0 5.5 2.3 8.0 7.8 0.8 6.1 0.0 1.5 28.1 2.0 117.6 0.1 0.0 4.2 153.7 532.0 30.9 0.1 5.4 0.1 10.1 3.0 152.7 0.5 22.1 20.4 0.2 70.6 88.4 4.9 0.0 2.3 26.6 37.2 0.1 1.6 29.5 0.3 6.7 0.2 1.2 4.0 2.6 3.5 61.2 0.5 7.6 1.2 9.3 7.2 3.6 0.1 57.3 35.1 158.2 10.1 57.2 16.4 71.3 13.8 18.9 16.0 6.2 15.4 11.3 19.1 5.4 13.7 12.3 9.1 12.4 16.1 6.0 21.5 15.3 23.4 24.4 25.0 19.5 25.2 26.9 26.8 29.2 27.8 29.0 26.5 30.1 18.1 6.4 8.9 57.1 22.4 1.1 0.9 0.8 1.2 0.8 16.1 10.8 60.0 0.0 2.4 1.8 0.0 0.3 23.6 0.1 1.9 0.6 12.0 0.9 2.4 13.2 0.0 11.3 20.6 1.8 0.4 10.7 5.6 1.6 193.9 128.2 12.5 2.5 15.2 13.5 21.6 0.4 0.0 46.5 25.1 35.8 14.9 40.3 3.6 77.8 36.1 4.7 36.0 48.2 4.3 0.7 0.0 14.7 12.8 0.4 0.0 0.2 2.2 0.3 13.1 33.5 18.5 0.7 0.7 0.6 1.7 0.4 40.5 30.1 0.1 0.7 ARHGEF9 "KIAA0424, PEM-2" ENSG00000131089 "Cdc42 guanine nucleotide exchange factor 9" O43307 X 63634967-63809274 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 88.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 184.3;Cone photoreceptor cells: 233.5;Rod photoreceptor cells: 320.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RH-30: 48.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035419, HPA055291" Approved Supported Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "HPA035419: AB_10669859, HPA055291: AB_2682774" "unprognostic (3.19e-1)" "unprognostic (6.15e-2)" "unprognostic (4.02e-2)" "unprognostic (2.67e-2)" "unprognostic (2.10e-1)" "unprognostic (2.14e-1)" "unprognostic (1.66e-1)" "unprognostic (1.98e-3)" "unprognostic (1.33e-2)" "unprognostic (3.79e-2)" "unprognostic (1.08e-3)" "unprognostic (1.67e-1)" "prognostic favorable (1.02e-5)" "unprognostic (4.56e-2)" "unprognostic (9.27e-2)" "unprognostic (3.15e-2)" "unprognostic (8.98e-2)" 7.7 15.6 32.6 6.4 39.3 4.1 10.6 5.1 51.0 8.4 5.2 13.6 15.8 9.3 7.1 11.2 7.7 8.0 35.9 46.2 36.6 13.2 5.6 6.3 6.3 13.1 14.3 16.2 5.2 15.0 15.7 5.8 14.3 13.8 14.3 88.1 6.3 14.6 5.9 9.1 13.4 17.2 10.0 6.9 8.9 2.8 26.7 9.5 8.2 8.9 7.3 14.3 6.5 27.2 6.3 9.7 20.2 10.3 7.6 11.1 1.2 12.3 11.8 12.8 9.8 0.6 6.8 14.1 8.7 8.0 10.8 0.2 8.4 14.5 15.1 18.5 6.6 13.7 4.5 0.6 4.5 6.7 4.2 12.2 6.9 5.9 18.5 11.9 7.1 14.8 1.5 20.8 14.0 10.0 12.6 3.3 16.4 6.2 12.1 22.9 48.2 13.5 7.8 6.0 0.1 5.1 5.6 9.8 6.7 8.4 7.5 8.9 3.4 7.1 6.4 34.6 5.1 7.8 6.5 10.2 8.7 10.7 5.1 0.8 1.4 1.3 4.5 2.0 3.2 2.2 2.7 3.1 2.2 2.9 3.3 2.9 1.1 8.4 1.4 1.8 2.6 1.9 32.6 39.3 5.1 51.0 46.2 36.6 13.1 14.3 14.3 10.0 26.7 27.2 9.2 9.6 11.4 59.4 20.3 5.7 6.5 8.7 12.5 184.3 26.0 17.4 45.9 7.2 10.0 11.0 233.5 5.0 19.4 18.2 13.7 6.3 2.0 6.5 9.8 10.8 20.9 3.8 105.9 8.8 1.4 11.8 24.5 6.0 14.5 20.0 11.7 10.7 10.5 82.4 90.5 16.0 12.2 5.7 6.3 6.2 15.5 8.2 14.2 33.7 3.8 29.9 34.0 89.0 50.5 7.9 14.5 15.4 12.4 4.3 19.1 17.3 9.3 320.8 0.0 12.7 22.0 1.9 3.4 11.2 6.0 4.4 21.8 39.6 21.8 6.1 ARMC6 MGC19595 ENSG00000105676 "Armadillo repeat containing 6" Q6NXE6 19 19033575-19060311 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 110.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 52.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041420, HPA041681" Supported Enhanced Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 15: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 2: Hepatocytes - Metabolism" Cytosol "HPA041420: AB_2677469, HPA041681: AB_10793928" "unprognostic (2.01e-2)" "unprognostic (3.34e-2)" "unprognostic (1.62e-1)" "unprognostic (1.63e-1)" "unprognostic (2.11e-2)" "unprognostic (1.65e-2)" "unprognostic (3.55e-2)" "unprognostic (2.43e-1)" "unprognostic (8.98e-2)" "unprognostic (2.36e-1)" "unprognostic (7.04e-3)" "unprognostic (1.05e-1)" "unprognostic (1.11e-1)" "unprognostic (6.37e-2)" "unprognostic (1.70e-1)" "unprognostic (3.73e-2)" "unprognostic (1.40e-1)" 11.9 16.6 20.4 11.4 20.4 16.7 11.7 21.6 27.8 13.9 19.8 12.4 10.0 14.7 6.1 18.7 11.7 6.9 17.9 21.2 21.7 16.9 110.5 11.9 15.8 22.9 21.2 12.0 11.2 11.9 17.8 8.8 22.7 15.6 8.9 7.7 13.3 8.0 21.3 12.7 12.3 9.1 19.5 17.8 12.3 24.0 20.3 23.2 19.4 18.2 12.4 14.4 12.6 20.8 64.1 42.8 30.7 38.0 14.5 24.7 39.7 40.3 23.5 64.5 47.7 59.8 56.0 96.3 63.8 34.1 23.8 31.8 73.7 47.8 35.5 20.4 104.0 48.5 39.0 49.0 32.0 87.1 54.3 31.2 44.9 44.0 30.7 14.5 41.6 56.3 86.4 36.0 36.0 78.0 93.2 70.5 71.5 71.9 86.8 76.3 27.7 68.9 31.9 42.6 70.5 30.6 32.4 41.1 33.9 20.7 35.0 54.1 27.2 33.0 28.8 47.3 83.8 27.5 53.2 93.2 27.3 117.1 44.0 10.6 19.0 5.3 22.1 20.3 16.6 13.4 12.0 19.3 28.3 15.1 15.7 18.0 3.8 30.6 16.7 18.2 23.4 18.3 20.4 20.4 21.6 27.8 21.2 21.7 22.9 21.2 22.7 19.5 20.3 20.8 7.1 0.0 5.9 4.6 10.7 6.6 6.8 9.2 9.1 14.1 11.5 11.4 5.9 17.2 8.9 12.9 12.5 20.5 21.3 12.3 7.9 16.0 25.5 6.3 11.8 10.2 15.0 13.7 4.0 10.7 20.3 10.7 12.2 9.6 1.3 11.1 8.2 52.4 20.7 5.0 5.0 10.9 6.1 15.6 6.0 47.9 10.2 9.2 5.4 0.0 14.9 16.4 20.6 5.0 5.5 10.8 10.8 8.2 10.3 12.4 10.4 12.3 4.5 17.9 13.1 7.4 9.1 22.0 31.0 10.0 10.1 13.0 10.3 16.5 17.3 5.5 ARMC7 FLJ22160 ENSG00000125449 "Armadillo repeat containing 7" Q9H6L4 17 75109952-75130272 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 39.5" "Cell type enhanced" "Detected in many" "Distal tubular cells: 35.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024229, HPA053076" Uncertain Supported Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA024229: AB_2059152, HPA053076: AB_2682036" "unprognostic (1.35e-1)" "prognostic favorable (2.98e-4)" "unprognostic (7.73e-2)" "unprognostic (5.84e-2)" "unprognostic (4.15e-2)" "unprognostic (5.32e-2)" "prognostic unfavorable (2.24e-5)" "unprognostic (2.84e-2)" "unprognostic (3.68e-1)" "unprognostic (4.28e-2)" "unprognostic (3.40e-2)" "unprognostic (4.86e-2)" "prognostic favorable (1.27e-4)" "unprognostic (1.93e-2)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "unprognostic (2.98e-2)" 7.4 6.7 7.3 5.8 7.5 4.1 7.4 12.7 9.0 7.7 7.7 12.4 9.6 7.0 4.8 11.2 6.6 4.7 8.8 7.6 7.7 39.5 13.2 12.3 7.0 7.3 7.1 5.2 7.0 6.6 7.0 5.8 7.6 11.8 6.9 2.7 8.9 6.4 5.5 12.0 11.9 4.0 7.0 14.0 11.4 7.3 7.9 8.2 9.9 3.9 6.4 8.7 9.3 7.9 15.2 30.2 8.9 8.5 7.0 4.3 9.4 8.3 9.0 15.9 14.3 25.3 14.7 9.0 10.8 7.7 8.7 12.4 14.6 6.1 7.6 8.7 23.2 17.5 13.4 15.9 15.5 13.5 16.1 5.6 11.4 10.0 5.8 7.7 14.6 14.5 15.8 17.6 5.3 21.7 25.9 14.8 4.5 32.8 22.6 14.6 18.0 16.8 35.6 27.4 8.3 11.9 15.6 15.7 18.6 15.2 18.4 12.9 11.3 16.1 14.9 6.4 13.1 14.7 5.5 12.7 7.2 9.6 11.8 31.7 13.7 28.5 18.0 9.9 15.8 13.4 12.9 15.1 12.7 10.0 9.8 14.9 18.6 15.7 7.9 11.1 20.8 11.7 7.3 7.5 12.7 9.0 7.6 7.7 7.3 7.1 7.6 7.0 7.9 7.9 6.6 12.8 8.8 1.3 10.4 4.6 2.8 5.8 2.2 6.0 6.0 5.1 2.5 7.2 5.2 22.0 0.0 14.1 10.1 28.6 35.2 8.7 6.2 4.6 3.0 9.0 6.0 1.7 3.0 9.4 8.3 4.1 8.6 5.1 10.8 4.4 14.3 4.6 15.2 0.0 2.9 9.8 6.1 7.5 3.3 12.2 5.3 9.7 12.4 1.9 13.9 3.3 11.3 2.5 1.8 11.3 27.1 3.8 6.4 4.8 15.8 15.4 7.2 3.4 19.7 2.2 4.6 3.8 5.9 4.4 4.5 4.9 8.7 6.6 12.4 3.8 ARMH1 "C1orf228, MGC33556, NCRNA00082, p40" ENSG00000198520 "Armadillo like helical domain containing 1" Q6PIY5 1 44674692-44725591 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 8.2;testis: 11.7" "Cell type enhanced" "Detected in some" "B-cells: 5.0;Collecting duct cells: 3.7;Endometrial ciliated cells: 13.1;Granulosa cells: 6.2;Hofbauer cells: 11.3;Macrophages: 5.1;T-cells: 5.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HL-60: 6.9;MOLT-4: 4.9;NB-4: 7.5;U-937: 9.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034769 Uncertain Uncertain Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 32: U-937 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "HPA034769: AB_10670979" "unprognostic (2.01e-5)" "unprognostic (4.28e-3)" "unprognostic (7.27e-2)" "prognostic favorable (8.64e-4)" "unprognostic (9.23e-2)" "unprognostic (7.43e-3)" "unprognostic (3.40e-1)" "unprognostic (2.16e-2)" "unprognostic (1.49e-2)" "unprognostic (9.34e-3)" "unprognostic (1.22e-2)" "unprognostic (9.38e-2)" "unprognostic (1.25e-10)" "unprognostic (1.99e-4)" "unprognostic (1.50e-1)" "unprognostic (6.77e-3)" "unprognostic (1.09e-3)" 0.4 1.1 1.7 0.2 2.2 2.2 0.7 1.1 2.6 0.8 4.5 0.5 0.2 1.7 3.5 0.5 8.2 0.7 0.2 2.3 1.3 0.9 4.2 1.0 0.6 2.6 4.0 2.6 0.5 1.9 3.3 0.3 2.1 0.8 0.3 4.2 0.7 0.6 0.1 0.8 0.3 0.3 1.8 0.3 0.7 11.7 1.9 0.4 0.6 0.0 0.3 0.3 0.3 2.2 0.2 0.3 1.8 0.1 0.5 2.1 0.5 0.0 0.2 0.5 0.3 0.4 3.8 0.2 0.2 0.8 0.9 0.5 0.0 0.0 0.0 1.0 0.2 0.9 2.6 0.6 0.2 6.9 4.1 1.7 0.2 0.7 0.0 1.3 0.2 0.3 0.1 0.7 0.2 0.0 4.9 7.5 0.1 0.5 0.0 2.7 0.1 2.2 0.7 0.0 1.2 0.8 0.0 1.2 0.9 1.2 0.3 3.6 0.0 0.3 0.3 0.3 0.0 0.3 0.1 0.2 0.3 9.9 0.4 8.7 2.1 6.1 0.2 0.7 0.1 0.6 1.1 0.8 1.0 0.9 1.6 1.5 1.0 0.4 0.0 4.8 0.0 1.4 1.7 2.2 1.1 2.6 2.3 1.3 2.6 4.0 2.1 1.8 1.9 2.2 0.5 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 1.2 1.7 0.0 0.0 0.0 3.7 0.0 0.4 1.3 0.0 1.9 0.7 0.0 13.1 0.6 0.1 0.0 0.0 0.0 0.4 0.2 0.3 0.0 0.7 0.0 6.2 0.0 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 5.2 0.9 0.0 0.0 ARSF ENSG00000062096 "Arylsulfatase F" P54793 X 3041471-3112727 "Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.9;kidney: 7.6;skin 1: 5.6" "Cell type enhanced" "Detected in some" "Astrocytes: 9.4;Distal tubular cells: 1.9;Inhibitory neurons: 4.6;Oligodendrocyte precursor cells: 2.5;Proximal tubular cells: 10.5" "Cancer enhanced" "Detected in some" "glioma: 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA000549 Uncertain Cytosol "Secreted in other tissues" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA000549: AB_1845055" "unprognostic (2.19e-2)" "unprognostic (8.88e-2)" "unprognostic (2.87e-1)" "unprognostic (5.41e-3)" "unprognostic (3.83e-1)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (9.72e-2)" "unprognostic (4.70e-1)" "unprognostic (6.33e-2)" "unprognostic (1.29e-1)" "unprognostic (3.05e-2)" "unprognostic (3.59e-1)" "unprognostic (1.23e-1)" "unprognostic (9.76e-2)" "unprognostic (1.48e-1)" 0.0 3.0 2.6 0.0 3.6 0.1 0.2 3.0 2.7 0.4 1.5 0.0 0.0 0.0 1.6 2.6 0.0 0.0 0.0 3.2 2.1 7.6 1.6 0.0 0.0 4.9 2.9 0.0 0.6 0.3 0.0 0.0 3.1 0.1 0.0 0.1 0.2 0.0 0.1 5.6 0.0 0.0 2.8 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.5 0.2 1.6 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 2.6 3.6 3.0 2.7 3.2 2.1 4.9 2.9 3.1 2.8 3.0 2.1 0.0 0.0 0.0 9.4 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 ASAP2 "CENTB3, DDEF2, KIAA0400, PAP, SHAG1" ENSG00000151693 "ArfGAP with SH3 domain, ankyrin repeat and PH domain 2" O43150 2 9206765-9405683 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 46.8" "Cell type enhanced" "Detected in many" "Astrocytes: 141.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 7 "basophil: 2.7" "Lineage enriched" "Detected in single" 7 "granulocytes: 2.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018615 Approved Supported Cytosol NA NA 260000 "Cluster 10: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "CAB018615: AB_2242947" "unprognostic (1.19e-1)" "unprognostic (2.66e-2)" "unprognostic (8.50e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (1.95e-1)" "unprognostic (1.18e-1)" "unprognostic (3.06e-2)" "unprognostic (1.08e-3)" "unprognostic (1.69e-1)" "unprognostic (2.07e-1)" "prognostic unfavorable (4.68e-4)" "unprognostic (8.33e-2)" "unprognostic (1.58e-3)" "unprognostic (3.14e-1)" "unprognostic (3.16e-1)" "unprognostic (2.64e-2)" "unprognostic (3.24e-2)" 12.4 3.3 3.9 5.6 11.8 0.7 6.8 11.0 9.1 11.4 4.7 17.7 13.8 12.8 10.0 8.8 10.7 10.1 9.6 6.3 7.0 23.7 3.8 10.0 2.8 8.1 6.1 7.7 7.8 9.9 9.5 10.4 8.9 5.2 16.1 8.8 5.6 9.2 2.5 13.1 13.6 13.9 0.8 1.5 24.3 46.8 3.2 2.7 19.1 6.4 3.1 8.5 7.8 7.0 34.8 19.9 35.8 21.2 26.0 35.9 5.9 34.4 27.7 24.9 24.9 13.9 51.0 0.1 29.8 39.2 54.7 32.8 19.9 60.6 30.6 25.1 8.1 8.0 15.4 24.1 63.1 0.0 2.4 13.6 24.5 30.1 96.8 74.5 51.9 6.4 3.7 3.6 97.8 21.1 10.2 2.0 16.9 49.5 23.2 19.5 53.7 6.5 48.7 26.7 15.6 59.6 28.7 18.9 30.7 18.7 13.1 5.5 81.8 41.6 1.9 32.5 31.7 0.0 0.2 0.1 30.4 0.2 54.2 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 3.9 11.8 11.0 9.1 6.3 7.0 8.1 6.1 8.9 0.8 3.2 7.0 41.0 19.2 8.3 141.0 1.4 37.2 22.8 16.6 14.8 28.2 8.4 7.7 1.6 4.3 12.9 35.0 0.0 1.6 0.3 60.7 50.9 15.4 67.0 14.9 20.8 36.1 9.1 0.0 76.2 14.0 0.3 26.0 52.5 26.8 1.3 9.7 51.8 4.4 12.8 6.7 46.5 40.8 20.3 4.4 12.9 50.7 2.8 10.6 33.8 39.4 7.9 20.4 0.0 48.2 55.0 62.1 45.4 3.8 0.2 33.8 21.6 31.1 12.9 5.3 26.3 24.9 35.3 39.8 8.9 5.5 32.1 0.4 1.2 1.6 21.4 53.3 ASL ASAL ENSG00000126522 "Argininosuccinate lyase" P04424 7 66075800-66094697 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Arginine biosynthesis, Urea cycle" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 396.4" "Cell type enhanced" "Detected in all" "Distal enterocytes: 294.6;Exocrine glandular cells: 218.6;Hepatocytes: 578.0;Paneth cells: 240.4;Proximal enterocytes: 259.9;Proximal tubular cells: 243.1" "Cancer enhanced" "Detected in all" "liver cancer: 52.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003696, HPA016646" Enhanced Approved Cytosol NA NA 12000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB003696: AB_425316, HPA016646: AB_1845096" "unprognostic (2.95e-2)" "prognostic unfavorable (4.05e-6)" "unprognostic (4.83e-1)" "unprognostic (4.18e-3)" "unprognostic (3.52e-2)" "unprognostic (1.21e-1)" "unprognostic (1.98e-1)" "unprognostic (2.07e-1)" "unprognostic (7.28e-2)" "unprognostic (2.49e-2)" "unprognostic (7.25e-2)" "unprognostic (4.95e-2)" "unprognostic (2.07e-2)" "unprognostic (3.69e-1)" "unprognostic (1.45e-1)" "unprognostic (2.19e-1)" "unprognostic (8.40e-3)" 21.7 16.1 5.9 16.7 6.0 23.9 22.0 6.6 8.5 18.2 8.7 53.8 60.7 17.0 6.7 28.7 18.1 27.7 16.9 5.9 8.0 61.2 396.4 27.4 10.3 7.4 7.1 19.7 37.1 15.1 19.8 9.1 9.8 19.5 35.7 2.4 18.3 9.8 8.7 15.1 45.6 10.1 6.2 30.5 43.9 4.5 7.6 5.3 24.9 6.9 8.8 19.3 19.8 6.7 48.4 18.9 11.2 36.7 26.3 18.1 22.1 34.0 31.8 49.5 43.6 43.7 59.0 15.9 53.7 48.5 36.6 13.4 7.1 59.1 11.1 10.5 8.9 18.8 17.9 77.2 48.8 24.0 51.3 38.3 19.5 31.8 51.8 12.5 48.1 11.3 34.4 27.8 25.4 36.6 4.8 28.9 15.8 65.5 26.1 12.1 11.0 51.6 31.9 31.6 18.4 24.3 32.3 109.7 12.3 11.4 46.0 19.7 55.1 53.7 30.8 23.5 45.2 30.2 16.9 19.0 55.0 41.5 49.5 34.2 42.6 50.8 16.9 46.6 15.1 21.8 11.5 13.4 46.2 13.8 8.2 8.5 7.3 73.7 36.1 2.5 23.4 27.3 5.9 6.0 6.6 8.5 5.9 8.0 7.4 7.1 9.8 6.2 7.6 6.7 34.5 19.2 61.4 5.2 20.4 5.5 21.4 24.2 9.1 12.7 24.5 20.4 9.2 124.4 25.8 31.3 22.9 20.7 25.4 294.6 52.8 73.7 4.0 41.2 12.1 30.7 54.0 47.1 9.4 218.6 45.7 14.4 115.7 34.1 44.5 12.0 42.8 578.0 46.0 15.2 9.7 126.5 16.2 41.2 17.6 6.3 9.3 22.3 8.8 1.9 48.3 7.2 34.0 2.5 4.8 118.3 240.4 8.2 23.4 14.9 259.9 243.1 42.8 13.2 13.1 16.9 17.5 3.2 5.7 19.5 4.3 22.3 18.0 13.5 189.4 22.0 ASMTL ENSG00000169093 "Acetylserotonin O-methyltransferase like" O95671 X 1403139-1453762 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" "Hydrolase, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 92.5;monocytes: 106.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 131.0" "Low region specificity" "Detected in all" "HPA003630, HPA021865" Supported Enhanced Cytosol NA NA 17000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" Cytosol "HPA003630: AB_1078230, HPA021865: AB_1845099" "unprognostic (3.89e-2)" "unprognostic (1.14e-3)" "unprognostic (2.28e-1)" "unprognostic (1.87e-2)" "unprognostic (7.99e-2)" "unprognostic (9.05e-2)" "unprognostic (8.17e-2)" "unprognostic (5.23e-2)" "unprognostic (8.40e-2)" "unprognostic (1.24e-1)" "unprognostic (1.91e-3)" "unprognostic (7.24e-2)" "unprognostic (3.26e-3)" "unprognostic (9.70e-2)" "unprognostic (8.38e-2)" "unprognostic (2.91e-1)" "unprognostic (2.20e-1)" 28.1 21.8 15.6 15.7 15.1 17.4 26.8 15.1 20.3 29.1 23.0 30.8 11.7 29.4 14.3 15.1 28.6 13.6 34.5 15.7 16.5 23.1 32.1 18.3 21.4 20.4 18.4 33.9 23.6 22.4 31.0 11.2 18.3 26.8 7.8 9.4 24.8 23.4 23.8 27.7 20.6 12.2 15.9 24.1 23.1 13.0 16.6 20.0 29.5 15.3 12.4 25.1 22.9 18.0 14.0 24.0 28.0 21.4 16.5 25.5 38.9 16.3 21.3 18.2 23.2 22.0 16.5 24.6 9.0 21.5 19.7 5.1 7.4 7.9 11.4 36.7 23.9 21.4 17.0 26.6 37.5 10.1 131.0 33.9 13.4 13.9 13.4 20.3 21.7 18.7 11.0 19.3 14.6 52.4 43.5 39.6 33.9 12.9 15.0 35.2 26.7 60.0 12.8 7.6 1.1 13.2 21.9 27.8 20.7 18.9 6.4 13.4 28.6 15.2 16.5 29.0 6.1 24.8 8.0 62.9 19.3 14.5 4.6 45.7 25.5 65.9 28.8 30.9 25.6 24.2 26.1 26.9 22.0 37.7 22.5 17.7 37.2 52.9 22.5 42.1 31.4 23.2 15.6 15.1 15.1 20.3 15.7 16.5 20.4 18.4 18.3 15.9 16.6 18.0 20.6 12.8 9.4 5.2 19.3 18.4 25.3 17.2 23.3 17.7 16.4 17.4 21.3 10.0 9.9 14.7 4.2 33.4 28.8 16.1 27.4 15.2 0.9 8.8 14.3 19.5 14.4 7.4 8.3 17.1 24.1 23.8 14.8 10.4 54.6 27.0 17.9 30.8 20.3 92.5 6.7 17.9 8.2 12.3 31.0 2.8 26.1 18.8 12.4 9.4 106.2 17.1 26.8 5.0 7.1 10.9 18.3 43.2 21.8 22.1 19.9 34.2 11.1 12.6 32.9 21.4 23.2 2.5 8.2 22.3 15.6 66.4 20.4 21.9 20.4 18.4 ASNS ENSG00000070669 "Asparagine synthetase (glutamine-hydrolyzing)" P08243 7 97851677-97872542 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Asparagine biosynthesis" Ligase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 121.4" "Cell type enhanced" "Detected in all" "Early spermatids: 233.9;Late spermatids: 217.0;Smooth muscle cells: 112.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 6 "B-cells: 8.9;T-cells: 14.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004924, HPA029318, HPA064737" Approved Enhanced Cytosol No No 47000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 22: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA004924: AB_2667295, HPA029318: AB_10602389, HPA064737: AB_2685341" "unprognostic (3.93e-2)" "unprognostic (2.51e-1)" "unprognostic (6.70e-2)" "prognostic unfavorable (4.24e-4)" "unprognostic (3.64e-1)" "prognostic unfavorable (8.79e-5)" "prognostic unfavorable (9.42e-6)" "unprognostic (2.28e-2)" "unprognostic (9.08e-2)" "unprognostic (1.89e-1)" "unprognostic (8.10e-3)" "unprognostic (2.53e-3)" "prognostic unfavorable (6.21e-7)" "unprognostic (5.33e-1)" "unprognostic (2.15e-1)" "unprognostic (6.21e-2)" "unprognostic (1.33e-1)" 17.3 18.0 49.9 19.5 52.3 13.7 17.8 52.7 66.3 19.9 28.2 24.5 9.7 19.0 31.5 27.0 20.1 11.2 19.4 55.3 51.0 28.9 9.3 25.6 28.8 58.7 43.5 20.8 121.4 26.3 44.1 4.6 59.4 21.5 19.9 35.3 41.6 14.5 8.0 22.9 22.6 18.0 43.6 30.3 46.0 33.3 49.7 13.3 27.5 8.6 25.7 21.7 18.6 63.8 124.6 46.6 51.6 415.9 35.3 57.9 109.1 85.7 62.5 41.6 134.8 64.2 49.3 101.7 45.3 189.8 92.3 57.4 118.2 151.2 102.2 122.4 85.3 31.0 24.6 50.8 347.8 207.1 89.9 106.2 508.8 55.8 361.2 23.5 41.4 94.4 177.1 365.2 76.3 286.5 6.4 54.4 68.1 308.4 125.4 14.0 10.0 282.7 28.4 22.3 218.1 156.7 23.2 136.7 499.0 60.6 57.1 139.1 7.6 21.6 138.5 56.7 40.7 412.6 239.7 401.1 288.7 90.3 220.8 1.9 0.3 0.4 3.6 1.1 4.3 8.9 7.2 3.4 1.5 6.0 10.1 5.5 1.8 2.0 1.0 0.2 14.2 3.3 49.9 52.3 52.7 66.3 55.3 51.0 58.7 43.5 59.4 43.6 49.7 63.8 5.8 9.6 7.2 11.1 14.4 12.4 26.1 20.9 6.2 20.3 9.7 11.2 7.6 7.2 12.3 9.2 25.0 3.1 6.7 10.5 7.9 30.9 233.9 2.9 8.6 6.7 24.4 46.1 51.8 61.6 7.8 8.9 14.3 4.5 8.2 8.8 2.9 1.3 1.1 25.2 48.6 19.6 32.6 1.3 3.2 217.0 9.6 2.1 8.8 5.6 7.3 9.2 5.2 16.1 16.9 36.6 14.7 9.4 19.9 26.1 1.1 3.9 4.5 24.9 6.6 10.2 112.3 3.4 20.2 5.5 10.9 5.6 11.2 6.0 9.9 14.9 ASNSD1 "FLJ20752, NBLA00058, NS3TP1" ENSG00000138381 "Asparagine synthetase domain containing 1" Q9NWL6 2 189661385-189670831 "Predicted intracellular proteins" "Amino-acid biosynthesis, Asparagine biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036132, HPA036133, HPA075042" Approved Approved Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA036132: AB_2674960, HPA036133: AB_10696650, HPA075042: AB_2686731" "unprognostic (1.32e-1)" "unprognostic (1.70e-1)" "unprognostic (4.88e-2)" "unprognostic (2.15e-3)" "prognostic favorable (4.54e-4)" "unprognostic (8.42e-2)" "prognostic unfavorable (8.66e-4)" "unprognostic (5.68e-2)" "unprognostic (1.35e-2)" "unprognostic (1.41e-3)" "unprognostic (2.09e-1)" "unprognostic (6.32e-3)" "unprognostic (8.98e-3)" "unprognostic (8.11e-2)" "unprognostic (2.52e-1)" "unprognostic (1.53e-1)" "unprognostic (1.86e-1)" 27.1 26.1 23.1 19.2 24.5 36.9 33.5 31.8 33.5 27.9 21.3 21.1 22.5 28.6 19.6 21.3 24.0 19.7 32.2 23.6 25.5 30.5 40.4 21.9 27.1 24.2 24.0 37.6 27.1 33.2 19.1 33.7 24.5 21.6 18.3 40.2 25.2 20.8 59.6 17.5 17.7 28.1 24.6 23.0 20.4 17.5 24.1 27.9 26.3 70.5 25.1 27.4 17.1 25.9 33.1 22.0 53.5 42.5 58.9 50.4 47.2 66.4 57.1 65.7 67.5 72.5 22.6 65.3 39.0 61.9 36.4 26.5 60.2 49.2 76.6 65.4 72.5 57.5 48.5 69.2 61.4 59.9 33.2 59.9 37.2 66.3 58.9 46.5 63.3 46.9 58.6 49.6 69.6 43.2 68.8 68.9 81.0 55.3 102.4 41.3 43.4 62.4 39.0 40.2 59.5 31.2 41.7 35.0 59.1 66.7 52.3 55.9 57.0 56.6 44.5 48.1 73.4 73.7 86.5 93.4 44.1 33.9 52.7 82.8 26.1 107.6 38.8 22.7 48.6 37.2 42.3 43.3 26.7 37.2 49.4 45.3 48.9 49.1 25.2 21.4 57.6 37.3 23.1 24.5 31.8 33.5 23.6 25.5 24.2 24.0 24.5 24.6 24.1 25.9 31.3 54.5 34.9 10.1 41.1 30.0 24.4 31.2 25.0 22.4 29.7 25.9 43.7 28.6 35.6 16.5 12.5 67.2 36.1 24.1 82.2 35.7 7.0 24.8 34.9 31.1 36.0 41.7 17.2 45.3 43.3 41.8 16.8 22.8 19.0 24.6 29.6 51.9 34.1 15.2 18.9 25.2 26.4 28.0 23.7 5.6 40.7 24.5 17.8 7.5 34.7 40.5 50.4 14.6 17.6 36.5 12.0 33.8 37.9 23.0 18.7 56.7 29.4 27.0 46.0 48.7 47.9 30.3 43.8 29.4 28.4 119.9 42.7 30.9 27.7 19.3 ASPA "ACY2, ASP" ENSG00000108381 Aspartoacylase P45381 17 3472374-3503405 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.0;kidney: 38.2" "Cell type enhanced" "Detected in many" "Leydig cells: 49.7;Melanocytes: 46.2;Oligodendrocytes: 217.0;Peritubular cells: 48.2;Proximal enterocytes: 37.5;Proximal tubular cells: 74.8" "Cancer enhanced" "Detected in some" "renal cancer: 7.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "ASC diff: 5.4;ASC TERT1: 4.1;CACO-2: 3.8;HSkMC: 7.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022142, HPA022145" Enhanced Supported Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA022142: AB_1845102, HPA022145: AB_1845103" "unprognostic (4.42e-2)" "unprognostic (4.79e-2)" "unprognostic (2.02e-2)" "unprognostic (2.79e-3)" "unprognostic (4.36e-2)" "unprognostic (5.01e-1)" "unprognostic (1.08e-3)" "unprognostic (3.57e-1)" "unprognostic (4.17e-1)" "unprognostic (3.43e-1)" "unprognostic (5.27e-2)" "unprognostic (6.27e-2)" "unprognostic (1.25e-1)" "unprognostic (7.07e-4)" "unprognostic (2.77e-1)" "unprognostic (4.68e-1)" "unprognostic (1.49e-1)" 13.9 4.3 25.9 1.8 46.4 1.8 4.1 27.6 40.9 7.5 14.2 4.3 11.2 4.5 6.0 4.9 5.5 3.6 2.7 25.8 27.7 38.2 15.0 3.5 1.5 30.4 35.4 2.9 1.0 0.8 0.8 3.5 29.5 4.1 4.9 2.8 1.8 5.0 11.9 5.2 15.6 3.1 24.7 5.4 4.4 6.6 42.4 0.6 2.1 15.0 0.7 6.3 4.3 69.0 0.2 0.1 0.5 0.5 5.4 4.1 0.3 0.2 0.1 0.2 0.1 3.8 0.2 0.6 0.2 0.7 0.3 0.3 0.3 0.1 0.2 2.0 0.1 0.4 0.7 0.2 0.5 0.4 0.4 7.5 0.3 0.4 0.1 0.1 0.1 0.4 0.3 1.1 0.2 0.2 0.2 0.6 0.4 0.2 0.3 0.3 0.3 0.6 0.2 1.1 0.4 0.3 1.1 0.3 0.9 0.4 0.3 0.2 0.4 0.6 0.4 0.4 0.3 0.7 0.4 0.4 0.2 0.4 0.5 1.1 0.1 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.1 0.3 0.2 0.2 0.7 0.3 0.1 0.2 0.1 0.0 25.9 46.4 27.6 40.9 25.8 27.7 30.4 35.4 29.5 24.7 42.4 69.0 5.1 9.6 1.5 12.1 0.1 5.2 1.5 1.6 6.2 5.5 2.1 0.8 1.3 2.8 1.0 25.8 0.0 0.0 0.0 0.3 7.9 0.2 5.0 0.1 4.1 1.1 2.4 2.7 0.6 0.2 0.1 15.0 2.0 0.2 0.0 0.1 3.9 11.5 0.2 8.4 0.4 0.8 2.0 0.8 1.5 2.5 49.7 0.8 46.2 3.7 0.0 4.1 0.0 1.5 217.0 0.0 2.5 48.2 0.2 0.4 37.5 74.8 0.1 0.5 0.0 8.5 11.6 11.1 0.6 0.7 1.7 0.1 0.4 28.3 1.8 2.7 ASPRV1 "FLJ25084, SASPase, Taps" ENSG00000244617 "Aspartic peptidase retroviral like 1" Q53RT3 2 69960089-69962265 "Human disease related genes, Plasma proteins, Predicted membrane proteins" "Aspartyl protease, Hydrolase, Protease" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "skin 1: 424.0" "Cell type enhanced" "Detected in some" "NK-cells: 3.1;Oligodendrocytes: 4.2;Spermatogonia: 3.3;Suprabasal keratinocytes: 10.7" "Group enriched" "Detected in many" 8 "head and neck cancer: 23.1;melanoma: 35.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 8.7" "Lineage enriched" "Detected in single" 10 "granulocytes: 8.7" "Cell line enhanced" "Detected in some" "NB-4: 2.9;REH: 4.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA034809, HPA034810" Enhanced Approved Cytosol NA NA 150000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 61: Skin - Cornification" "Cluster 14: REH - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" Cytosol "HPA034809: AB_2674343, HPA034810: AB_10601456" "unprognostic (4.75e-4)" "unprognostic (1.90e-3)" "unprognostic (2.34e-2)" "unprognostic (3.34e-2)" "unprognostic (2.65e-1)" "unprognostic (1.17e-2)" "unprognostic (1.93e-3)" "unprognostic (1.51e-1)" "unprognostic (1.36e-1)" "unprognostic (2.51e-1)" "unprognostic (4.19e-3)" "unprognostic (1.27e-1)" "unprognostic (4.01e-2)" "unprognostic (3.00e-1)" "unprognostic (1.74e-1)" "unprognostic (4.84e-2)" "unprognostic (2.43e-2)" 2.6 2.1 5.8 0.9 7.3 0.9 17.1 6.1 6.6 3.1 3.0 1.7 1.6 2.5 2.6 0.9 2.3 1.1 1.8 5.3 6.0 2.2 1.9 1.7 1.0 7.2 6.7 4.8 0.7 0.2 4.0 0.9 6.5 2.2 0.6 1.5 1.3 1.3 4.4 424.0 1.7 1.2 6.0 3.9 1.2 3.6 6.5 2.1 1.3 2.1 1.0 1.5 4.5 9.3 0.0 0.3 0.9 1.9 1.2 0.4 0.2 0.2 0.4 0.2 0.1 0.6 0.0 0.7 0.1 0.2 0.2 0.2 0.8 0.1 0.2 1.3 2.5 1.5 0.2 0.6 0.4 1.3 1.0 0.5 0.4 0.2 0.4 0.3 0.2 1.6 0.5 1.9 0.2 0.3 1.1 2.9 1.0 0.2 0.2 4.9 0.5 0.3 0.0 0.0 1.0 0.2 0.1 0.7 0.8 0.2 0.0 0.5 0.1 0.0 0.9 0.0 0.2 2.0 1.3 1.4 0.1 0.9 1.0 0.0 0.1 1.5 0.5 0.1 0.5 0.0 0.2 0.4 0.0 0.1 0.1 0.4 8.7 0.3 0.0 0.8 0.7 0.4 5.8 7.3 6.1 6.6 5.3 6.0 7.2 6.7 6.5 6.0 6.5 9.3 1.1 0.0 0.0 1.3 0.0 0.4 0.1 0.2 0.0 1.1 0.5 0.9 2.6 0.0 0.1 1.8 0.0 0.3 0.1 0.5 0.0 0.1 0.1 0.4 0.5 0.8 0.0 0.0 1.0 0.2 0.0 0.7 0.0 0.4 0.0 1.1 1.4 0.1 0.2 0.0 1.5 0.9 0.0 0.3 0.6 0.5 0.9 0.3 0.0 1.0 0.2 1.2 3.1 1.5 4.2 0.3 0.0 0.7 0.1 0.2 1.1 0.9 0.2 1.6 0.0 0.7 1.1 1.4 3.3 0.0 10.7 0.4 0.2 0.5 0.2 0.1 ATG16L1 "APG16L, ATG16A, ATG16L, FLJ10035, WDR30" ENSG00000085978 "Autophagy related 16 like 1" Q676U5 2 233210051-233295674 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012577, HPA063900" Supported Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 5: NTERA-2 - Transcription" "Cluster 44: Endometrium - Transcription" Cytosol "HPA012577: AB_1845155, HPA063900: AB_2685146" "unprognostic (1.24e-1)" "unprognostic (1.07e-1)" "unprognostic (3.57e-2)" "unprognostic (2.22e-3)" "unprognostic (1.89e-1)" "unprognostic (4.49e-1)" "prognostic unfavorable (1.48e-5)" "unprognostic (2.51e-1)" "unprognostic (1.80e-1)" "unprognostic (1.85e-2)" "unprognostic (6.66e-3)" "unprognostic (1.16e-2)" "prognostic unfavorable (1.70e-4)" "unprognostic (3.93e-2)" "unprognostic (1.41e-1)" "unprognostic (2.41e-1)" "unprognostic (2.08e-1)" 7.6 7.8 7.0 3.8 7.5 14.3 8.8 7.9 8.4 8.1 12.8 11.1 5.0 9.6 5.5 11.6 7.1 3.3 10.7 7.3 6.6 9.2 15.1 7.6 5.8 6.5 6.3 8.5 8.6 5.3 5.5 4.0 6.9 12.1 5.2 5.6 11.5 4.3 19.9 17.2 11.1 5.2 6.3 11.5 11.1 13.5 6.5 5.9 11.2 6.1 5.2 11.5 8.2 7.7 13.3 12.2 4.9 8.5 12.4 8.0 14.0 11.4 9.3 9.6 8.9 8.9 9.7 3.1 3.7 8.9 14.3 7.7 9.8 6.4 9.8 6.2 7.7 7.1 9.1 14.6 9.1 5.6 9.0 5.3 9.1 11.5 8.7 7.2 9.0 4.7 7.6 2.9 10.2 9.3 6.7 11.2 19.1 14.1 17.6 4.8 10.3 2.6 9.9 8.4 8.8 6.5 7.8 8.5 8.5 7.4 5.3 7.1 10.7 6.2 5.4 9.6 10.3 6.5 3.9 6.1 10.5 5.7 10.2 0.0 1.7 2.9 4.8 1.4 3.7 2.0 3.1 4.4 1.4 2.2 3.5 3.5 1.2 4.1 4.7 0.7 3.8 2.1 7.0 7.5 7.9 8.4 7.3 6.6 6.5 6.3 6.9 6.3 6.5 7.7 6.1 6.4 8.2 5.2 7.4 9.1 4.6 5.2 3.4 8.4 12.0 6.6 5.6 7.2 11.6 5.5 4.2 4.6 20.9 13.9 5.9 8.3 1.2 16.4 10.9 6.4 9.0 3.8 31.0 6.7 6.2 5.2 8.2 31.8 9.5 6.4 6.1 10.2 5.6 1.7 25.6 5.1 6.1 6.3 5.7 1.7 4.1 5.1 10.6 8.4 6.6 7.1 4.1 11.6 21.4 16.8 8.0 3.8 8.1 7.1 9.2 5.6 11.5 19.5 6.6 5.8 6.9 11.0 17.6 7.3 13.2 3.7 19.2 5.1 8.4 6.0 ATP6V0A4 "a4, ATP6N1B, ATP6N2, RDRTA2, RTA1C, RTADR, Stv1, Vph1, VPP2" ENSG00000105929 "ATPase H+ transporting V0 subunit a4" Q9HBG4 7 138706294-138799560 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "kidney: 63.6;salivary gland: 78.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 16.5;Cytotrophoblasts: 13.4;Distal tubular cells: 31.3;Ionocytes: 57.0" "Cancer enriched" "Detected in many" 8 "renal cancer: 25.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "SK-BR-3: 55.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018029, HPA064555" Enhanced Uncertain Cytosol NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA018029: AB_1845190, HPA064555: AB_2685284" "unprognostic (1.99e-2)" "unprognostic (8.60e-3)" "unprognostic (1.12e-2)" "unprognostic (3.10e-2)" "unprognostic (1.43e-1)" "unprognostic (6.53e-2)" "unprognostic (4.63e-2)" "unprognostic (4.28e-1)" "unprognostic (1.35e-1)" "unprognostic (9.79e-3)" "unprognostic (1.73e-1)" "prognostic favorable (1.32e-6)" "unprognostic (4.35e-1)" "unprognostic (1.56e-1)" "unprognostic (1.02e-1)" "unprognostic (1.10e-2)" 0.2 0.0 0.3 0.0 0.4 0.0 4.7 0.1 0.5 3.7 3.1 0.0 0.1 0.1 1.2 4.9 0.0 0.0 0.0 0.6 0.2 63.6 0.0 0.4 0.0 0.3 0.2 0.0 0.1 1.6 0.1 2.5 0.2 0.9 0.0 0.0 78.4 1.5 0.0 10.2 0.0 0.0 0.2 0.0 0.1 0.2 0.3 0.4 0.0 0.0 3.7 0.1 0.2 0.3 0.2 0.5 0.0 0.0 0.0 0.0 0.5 0.8 0.1 0.6 0.6 1.8 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.7 5.0 1.9 0.0 0.1 0.0 0.1 0.1 0.6 0.0 4.5 0.2 0.0 0.0 0.1 55.7 1.9 2.9 0.1 0.0 0.2 0.6 1.3 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.1 0.5 0.6 0.2 0.3 0.2 0.2 0.2 0.3 0.3 0.0 0.0 1.1 0.3 0.0 0.0 1.1 0.9 0.0 0.0 2.5 1.4 0.5 0.0 1.7 16.5 2.1 13.4 0.3 0.0 31.3 0.0 2.2 0.9 0.1 0.1 0.0 0.0 1.4 0.0 0.7 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.7 0.0 1.2 0.0 57.0 0.0 0.0 2.8 0.3 0.0 7.2 1.0 0.0 0.0 0.0 6.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.3 4.4 0.1 0.0 0.0 0.1 0.6 0.7 0.0 0.1 5.1 0.2 0.0 0.0 1.3 ATP6V0B "ATP6F, HATPL, VMA16" ENSG00000117410 "ATPase H+ transporting V0 subunit b" Q99437 1 43974487-43978295 "Metabolic proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ionocytes: 1694.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 2268.9" "Group enriched" "Detected in all" 4 "dendritic cells: 769.4;granulocytes: 2268.9;monocytes: 1046.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044281 Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA044281: " "unprognostic (1.38e-1)" "unprognostic (2.16e-1)" "unprognostic (1.27e-1)" "unprognostic (5.69e-2)" "unprognostic (5.31e-2)" "unprognostic (3.92e-2)" "prognostic unfavorable (4.79e-4)" "unprognostic (1.32e-1)" "unprognostic (1.82e-2)" "unprognostic (7.23e-2)" "prognostic favorable (3.24e-4)" "unprognostic (6.13e-2)" "prognostic favorable (3.62e-6)" "unprognostic (5.55e-2)" "unprognostic (1.93e-1)" "unprognostic (1.29e-1)" "prognostic unfavorable (8.87e-4)" 78.9 162.2 222.2 68.3 225.4 286.4 79.4 234.5 267.0 63.8 253.8 94.8 61.1 57.5 97.3 101.0 61.5 64.5 107.2 231.3 256.2 233.8 168.3 115.8 71.6 235.4 232.9 49.7 172.0 182.0 157.5 76.6 251.1 101.4 90.8 106.6 112.1 60.7 138.6 98.9 83.8 55.7 232.2 143.7 124.9 56.7 244.0 60.1 101.7 84.0 74.7 92.6 70.9 255.4 150.4 135.9 99.4 129.1 149.3 78.0 142.9 134.1 168.5 217.1 183.6 143.2 144.5 140.3 119.7 119.0 253.2 118.4 233.4 170.1 99.8 135.4 266.4 175.0 209.7 195.1 238.0 262.7 307.9 97.4 219.6 235.3 206.5 136.7 105.1 167.3 189.5 260.9 177.1 147.3 103.2 411.3 182.4 184.8 271.1 150.7 108.1 371.7 225.2 159.1 260.9 137.2 89.0 303.1 319.0 111.4 128.8 419.5 62.8 119.0 105.7 222.6 311.4 241.9 397.5 150.3 161.2 355.5 188.5 528.7 1046.6 892.1 161.2 652.9 161.5 321.1 171.0 156.8 630.7 271.9 129.7 130.1 2268.9 124.4 618.8 769.4 187.2 1450.9 222.2 225.4 234.5 267.0 231.3 256.2 235.4 232.9 251.1 232.2 244.0 255.4 125.1 80.1 126.9 26.4 176.6 335.9 161.9 577.2 173.6 238.7 241.5 219.1 101.7 144.4 367.7 283.3 102.2 197.4 216.0 242.1 201.5 347.8 4.4 186.6 93.6 136.9 224.0 114.6 36.5 328.5 223.3 118.9 114.7 207.9 206.7 77.0 102.1 241.0 815.7 129.5 40.5 306.2 1694.7 347.6 454.5 12.9 78.9 489.8 281.1 24.4 379.2 220.2 103.0 28.6 62.4 379.0 382.7 65.5 301.2 355.1 186.0 223.5 244.1 231.7 78.9 77.4 444.3 116.6 197.9 192.9 358.3 496.5 121.2 135.9 241.8 337.5 ATP6V0C "ATP6C, ATP6L, ATPL, VATL, Vma3" ENSG00000185883 "ATPase H+ transporting V0 subunit c" P27449 16 2513952-2520218 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 115.3;Basal squamous epithelial cells: 363.7;Gastric mucus-secreting cells: 128.0;Macrophages: 152.4;Plasma cells: 235.0;Squamous epithelial cells: 385.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065100 Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 59: Non-specific - Transcription" Cytosol "HPA065100: AB_2685421" "unprognostic (1.30e-1)" "unprognostic (1.30e-1)" "unprognostic (1.12e-1)" "unprognostic (5.96e-2)" "unprognostic (7.67e-2)" "unprognostic (2.31e-1)" "unprognostic (4.20e-3)" "unprognostic (1.44e-2)" "unprognostic (4.63e-2)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "unprognostic (6.78e-2)" "prognostic favorable (1.07e-6)" "unprognostic (1.46e-1)" "unprognostic (1.34e-2)" "unprognostic (2.85e-1)" "unprognostic (5.04e-2)" 203.2 247.2 150.2 95.4 176.0 182.7 165.2 82.8 252.8 178.7 66.7 172.0 95.0 154.8 32.9 337.0 147.8 23.2 211.8 204.1 196.7 414.4 207.1 230.5 50.8 136.5 139.7 154.3 140.5 103.9 327.2 62.1 141.6 144.2 29.7 110.5 214.2 48.3 301.0 281.2 164.4 30.0 72.4 222.0 175.7 143.9 147.5 44.9 166.8 54.0 31.0 134.4 207.4 135.7 154.4 174.5 84.6 125.9 105.3 54.3 203.5 234.4 72.1 98.2 90.4 163.9 206.4 81.8 209.3 106.0 154.2 193.4 90.7 137.6 45.1 207.1 295.5 95.2 128.1 201.7 152.6 139.9 274.3 98.2 104.4 118.6 59.6 90.8 68.5 88.2 214.5 143.0 80.0 323.5 141.3 363.3 176.3 99.4 211.4 240.8 73.5 251.1 163.8 97.4 277.6 224.4 201.3 215.5 204.4 74.8 222.5 175.9 171.4 154.3 184.6 229.6 160.1 280.9 351.5 146.5 137.1 105.3 161.4 89.4 123.2 203.4 51.4 139.4 53.3 58.5 46.8 56.5 76.6 55.0 52.1 47.0 165.8 52.7 171.7 105.1 50.8 78.8 150.2 176.0 82.8 252.8 204.1 196.7 136.5 139.7 141.6 72.4 147.5 135.7 1.8 25.6 49.2 38.2 115.3 1.0 0.2 0.4 363.7 0.5 1.1 0.6 0.1 0.0 18.3 1.8 0.0 0.5 3.4 3.4 0.0 0.8 0.0 4.3 2.6 12.7 0.0 73.4 72.7 0.2 1.0 48.8 128.0 3.6 17.7 0.6 1.4 0.7 1.0 0.0 107.3 0.7 0.0 1.3 0.8 0.2 0.6 152.4 0.0 39.4 0.3 0.4 0.0 36.7 53.0 0.6 0.2 0.0 235.0 0.2 2.4 1.1 25.1 0.8 0.0 0.7 17.0 0.8 1.1 385.2 1.0 1.2 72.7 0.4 2.3 0.2 ATPAF2 "ATP12, Atp12p, LP3663, MGC29736" ENSG00000171953 "ATP synthase mitochondrial F1 complex assembly factor 2" Q8N5M1 17 17977409-18039209 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SuSa: 104.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023329, HPA059422" Supported Enhanced Cytosol No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 12: NES - Nervous system development" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA023329: AB_1845209, HPA059422: AB_2684011" "unprognostic (3.16e-2)" "unprognostic (1.98e-2)" "unprognostic (4.40e-2)" "prognostic favorable (4.95e-4)" "unprognostic (1.82e-1)" "unprognostic (1.27e-1)" "unprognostic (1.22e-1)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (1.55e-1)" "unprognostic (2.70e-3)" "unprognostic (1.67e-2)" "prognostic favorable (6.00e-5)" "unprognostic (1.32e-1)" "unprognostic (2.53e-1)" "unprognostic (5.15e-1)" "unprognostic (2.62e-2)" 8.6 18.5 7.4 8.6 7.6 15.9 8.7 8.3 11.1 8.4 8.3 11.1 8.7 6.8 8.7 14.4 8.1 4.9 23.9 7.5 9.1 16.1 19.7 7.8 10.5 7.9 8.1 7.3 9.8 26.3 9.3 7.7 8.4 9.1 10.4 6.4 10.7 6.6 24.7 14.6 10.2 8.4 7.8 10.4 12.0 10.9 7.8 10.8 10.6 27.8 14.5 9.1 9.5 8.4 13.0 24.1 15.4 14.7 15.1 16.2 15.6 11.2 16.4 23.7 20.1 31.8 19.3 26.0 24.6 19.5 13.1 19.9 14.8 24.1 20.7 20.9 11.7 5.8 14.8 18.6 25.5 8.2 17.3 19.5 16.8 21.4 11.9 16.7 27.4 21.3 9.3 8.9 13.1 26.8 19.4 12.8 10.4 48.3 13.3 19.8 27.1 29.9 19.0 11.4 9.9 13.5 14.9 7.6 14.0 104.2 24.4 16.2 11.6 6.0 12.4 22.2 10.9 6.2 8.4 9.6 10.7 11.9 31.4 7.8 41.5 14.7 9.3 28.6 10.4 27.9 6.9 8.9 49.2 19.7 10.7 8.0 3.0 8.9 22.3 41.6 12.9 20.7 7.4 7.6 8.3 11.1 7.5 9.1 7.9 8.1 8.4 7.8 7.8 8.4 8.8 6.4 7.8 9.4 20.3 15.3 12.0 23.7 9.6 10.5 13.9 10.8 28.2 20.0 14.4 12.9 33.3 32.5 20.7 10.9 66.5 19.3 52.9 10.5 6.0 10.0 14.5 13.7 13.7 12.3 30.9 9.1 8.2 8.5 13.3 25.7 9.3 20.8 45.5 10.1 14.1 18.2 16.2 22.3 22.5 42.6 6.5 18.2 17.8 7.5 28.1 13.8 13.4 9.0 9.6 16.0 24.4 6.8 18.6 13.8 25.8 58.8 17.2 17.7 0.0 8.4 10.4 28.2 20.9 17.6 18.9 28.7 9.0 15.9 20.5 12.3 ATRN "DPPT-L, MGCA" ENSG00000088812 Attractin O75882 20 3471018-3651118 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 101.6;Inhibitory neurons: 101.1;Oligodendrocyte precursor cells: 89.5;Oligodendrocytes: 85.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008853 Approved Approved Cytosol "Secreted to blood" NA NA 27000000000 "Cluster 52: Eosinophils - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA008853: AB_1078248" "unprognostic (6.42e-2)" "unprognostic (1.10e-1)" "unprognostic (2.04e-1)" "unprognostic (2.02e-1)" "unprognostic (2.52e-1)" "unprognostic (5.27e-2)" "unprognostic (1.65e-1)" "unprognostic (3.99e-2)" "unprognostic (4.28e-1)" "unprognostic (3.40e-2)" "unprognostic (4.61e-2)" "unprognostic (1.59e-1)" "prognostic favorable (2.19e-6)" "unprognostic (3.71e-2)" "unprognostic (9.49e-2)" "unprognostic (2.77e-1)" "unprognostic (3.91e-2)" 12.8 19.1 10.5 10.3 12.2 8.6 17.2 9.3 13.2 16.5 8.9 11.8 55.8 11.8 15.6 10.4 11.7 13.9 19.1 13.4 12.2 23.9 62.8 14.4 7.5 8.0 8.7 14.0 20.2 40.1 8.7 22.6 9.0 12.8 12.3 24.2 13.9 13.2 11.6 14.9 33.4 14.9 11.3 13.8 24.0 16.6 10.8 7.8 32.3 14.2 9.6 15.7 9.1 15.8 40.8 37.6 21.9 18.4 37.9 61.5 28.1 26.6 37.5 27.4 23.1 16.3 27.1 0.0 17.5 37.4 33.8 55.6 15.0 58.1 36.4 4.5 12.8 12.7 10.0 35.1 22.8 27.2 8.3 33.1 46.0 29.0 27.8 34.3 36.0 8.7 20.2 19.2 27.0 11.7 11.1 10.4 14.7 13.2 22.3 9.2 50.9 30.8 24.8 28.5 12.9 20.2 26.7 48.9 36.3 21.3 26.2 25.5 44.7 29.0 17.0 30.8 26.6 13.4 20.1 0.1 17.9 17.9 29.6 3.6 3.2 2.0 2.3 2.8 1.0 1.4 1.2 1.4 2.8 1.7 2.0 1.7 0.0 1.5 3.1 2.6 1.8 1.0 10.5 12.2 9.3 13.2 13.4 12.2 8.0 8.7 9.0 11.3 10.8 15.8 11.1 16.0 10.4 70.2 5.8 6.4 4.3 14.1 6.8 22.5 9.9 8.8 12.6 20.0 10.3 11.0 37.5 7.4 8.0 6.5 1.9 8.2 7.1 9.9 15.1 11.1 9.6 7.4 101.6 14.6 8.4 12.7 20.4 11.8 7.0 39.3 17.9 50.9 10.4 37.0 101.1 10.7 4.1 14.2 6.7 5.4 12.5 11.5 7.2 64.6 10.1 11.8 5.2 89.5 85.7 10.0 14.3 7.9 11.4 7.0 34.6 7.3 10.2 20.1 32.9 14.3 10.9 21.3 21.1 8.5 7.2 5.1 5.8 21.0 12.6 5.2 ATXN2 "ATX2, SCA2, TNRC13" ENSG00000204842 "Ataxin 2" Q99700 12 111443485-111599676 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Amyotrophic lateral sclerosis, Neurodegeneration, Parkinsonism, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 209.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018295, HPA020339, HPA021146" Enhanced Enhanced Cytosol NA NA 9600 "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Cytosol "HPA018295: AB_1845130, HPA020339: AB_1845131, HPA021146: AB_1845132" "unprognostic (3.08e-1)" "unprognostic (1.52e-1)" "unprognostic (1.29e-1)" "unprognostic (7.82e-2)" "unprognostic (1.55e-1)" "unprognostic (3.53e-1)" "prognostic unfavorable (2.66e-4)" "unprognostic (2.34e-1)" "unprognostic (2.77e-2)" "unprognostic (1.09e-1)" "unprognostic (1.30e-1)" "unprognostic (4.58e-1)" "unprognostic (5.28e-2)" "unprognostic (1.81e-1)" "unprognostic (2.58e-1)" "unprognostic (3.00e-1)" "unprognostic (3.40e-2)" 19.6 23.5 20.5 11.2 21.9 8.0 17.5 22.8 30.3 21.6 20.8 22.8 11.2 21.7 13.9 14.2 20.4 12.0 22.2 20.5 29.9 17.5 20.1 19.7 9.5 25.2 26.0 25.9 13.8 18.6 21.9 16.3 24.5 19.4 11.6 15.7 14.5 15.6 25.8 15.6 14.9 18.3 18.6 14.1 16.3 23.2 22.7 12.8 17.1 20.8 8.9 19.6 18.3 25.8 31.0 38.0 30.3 38.2 35.9 29.0 29.4 35.8 25.9 28.8 23.4 25.2 25.7 25.8 14.2 47.7 23.8 25.5 45.0 18.2 36.0 23.3 33.9 38.2 22.8 42.4 49.7 27.1 21.4 32.4 20.1 38.0 42.6 48.0 27.8 20.2 46.8 13.1 37.2 24.7 23.2 24.2 30.1 19.4 24.6 21.8 18.6 19.2 30.1 34.5 28.7 25.2 38.5 49.3 24.7 29.1 30.9 16.5 34.9 36.9 21.6 30.4 20.6 23.4 30.0 22.5 19.0 20.9 23.5 4.5 3.6 5.8 3.9 3.4 5.2 5.1 4.9 5.3 5.0 2.7 4.1 3.6 3.5 5.6 6.4 2.7 2.2 2.8 20.5 21.9 22.8 30.3 20.5 29.9 25.2 26.0 24.5 18.6 22.7 25.8 43.0 80.1 72.6 175.3 26.7 35.3 34.3 18.4 35.9 101.0 33.6 26.3 36.6 30.0 36.6 36.8 135.5 32.5 28.9 25.6 3.9 26.0 11.1 87.2 72.2 43.9 41.4 34.9 146.7 25.3 25.4 40.0 23.9 50.3 23.5 67.2 63.5 38.1 24.5 65.6 171.8 26.7 24.4 35.9 35.9 11.9 65.6 30.6 32.0 106.8 35.1 32.6 48.4 128.7 209.6 32.6 16.0 47.4 24.2 43.0 22.7 16.9 56.0 90.4 32.9 41.5 46.6 78.0 70.7 25.7 35.2 46.9 27.4 68.7 31.5 42.2 ATXN2L "A2D, A2lp" ENSG00000168488 "Ataxin 2 like" Q8WWM7 16 28823035-28837237 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041506, HPA043391, HPA071955" Approved Enhanced Cytosol NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Cytosol "HPA041506: AB_2677521, HPA043391: AB_2678459, HPA071955: AB_2686478" "unprognostic (1.64e-2)" "unprognostic (1.72e-1)" "unprognostic (7.33e-3)" "unprognostic (1.03e-2)" "unprognostic (3.11e-1)" "unprognostic (6.63e-2)" "prognostic unfavorable (9.85e-4)" "unprognostic (5.59e-2)" "unprognostic (7.56e-2)" "unprognostic (1.02e-1)" "unprognostic (2.11e-1)" "unprognostic (2.83e-2)" "prognostic unfavorable (7.99e-7)" "unprognostic (1.79e-1)" "unprognostic (1.61e-2)" "unprognostic (7.22e-2)" "unprognostic (2.98e-1)" 67.8 78.2 80.2 51.6 86.2 82.9 65.3 89.9 116.8 83.3 72.7 75.6 43.8 71.3 20.9 81.9 77.8 29.2 68.8 82.2 82.2 85.7 96.1 85.9 62.7 83.2 80.4 81.3 96.8 33.7 116.4 39.0 83.4 80.6 27.0 56.5 70.1 27.9 63.8 76.9 86.3 33.4 75.5 117.0 82.6 178.9 83.5 52.5 83.0 23.7 46.9 75.5 77.7 86.0 77.8 97.6 99.0 112.1 59.9 61.5 116.1 76.3 73.7 82.1 91.3 124.1 90.1 178.6 95.4 54.4 128.6 110.2 93.9 76.9 90.5 140.9 83.3 119.5 124.3 127.4 107.5 135.9 161.2 78.8 90.1 116.4 166.1 72.4 73.2 174.4 158.9 219.9 68.4 109.9 166.1 228.0 100.6 46.9 67.2 216.4 68.5 125.6 48.9 79.6 102.8 81.9 44.6 83.5 95.8 62.3 91.3 141.0 88.2 101.2 83.6 65.8 106.2 311.9 238.1 159.4 76.3 128.1 119.6 0.4 2.1 1.4 1.6 1.9 1.6 4.3 1.9 2.0 1.6 2.9 1.8 2.3 2.4 1.9 1.6 5.6 1.7 1.1 80.2 86.2 89.9 116.8 82.2 82.2 83.2 80.4 83.4 75.5 83.5 86.0 30.2 28.9 33.3 26.1 48.2 36.6 25.1 20.2 66.0 31.6 29.8 26.3 2.1 21.5 19.8 20.2 45.9 23.0 39.1 19.8 1.9 17.8 71.7 37.7 34.9 27.8 24.6 23.1 37.3 20.2 21.9 20.8 31.6 53.1 25.9 23.4 27.1 14.7 24.8 26.9 37.5 23.4 14.2 29.3 33.3 25.7 21.5 36.5 8.8 24.4 26.4 10.0 33.0 18.6 31.5 32.2 19.4 19.9 65.1 33.0 19.7 4.8 18.8 48.9 13.1 28.9 22.1 83.9 28.3 46.3 31.1 34.3 48.4 24.5 23.4 27.4 AZIN2 "ADC, KIAA1945, ODC-p, ODC1L, ODCp" ENSG00000142920 "Antizyme inhibitor 2" Q96A70 1 33081104-33123492 "Metabolic proteins, Predicted intracellular proteins" "Polyamine biosynthesis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 32.1" "Group enriched" "Detected in many" 6 "Early spermatids: 233.2;Late spermatids: 855.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "basophil: 6.4;plasmacytoid DC: 18.9" "Group enriched" "Detected in many" 8 "dendritic cells: 18.9;granulocytes: 6.4" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 11.0;SK-MEL-30: 14.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028527 Approved Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 78: Testis - Spermatogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA028527: AB_10602077" "unprognostic (5.33e-2)" "unprognostic (1.60e-1)" "unprognostic (2.16e-3)" "unprognostic (7.50e-2)" "unprognostic (8.28e-2)" "unprognostic (4.56e-2)" "unprognostic (1.15e-4)" "unprognostic (9.19e-3)" "unprognostic (3.89e-2)" "unprognostic (1.54e-2)" "unprognostic (1.06e-3)" "unprognostic (2.16e-1)" "unprognostic (3.18e-1)" "unprognostic (6.91e-2)" "unprognostic (2.91e-1)" "unprognostic (9.45e-2)" "unprognostic (2.41e-1)" 1.4 3.8 7.1 0.8 8.4 0.1 2.1 8.4 9.4 3.8 5.4 3.5 0.4 2.4 1.1 0.9 4.3 1.9 3.6 7.5 7.3 2.7 0.7 1.3 1.0 8.3 7.8 6.3 1.6 3.3 3.5 0.5 8.0 2.2 1.1 3.0 2.2 1.7 1.0 1.4 1.3 1.4 9.8 1.1 1.0 32.1 7.6 1.1 2.5 1.9 1.2 1.4 2.1 12.9 0.5 0.0 1.8 0.3 0.9 3.0 0.2 0.6 1.8 1.3 1.1 0.0 1.5 0.0 0.8 0.5 1.0 0.2 0.9 0.2 0.7 0.0 0.0 0.4 0.0 0.0 3.6 0.0 1.6 3.5 2.0 1.5 1.3 11.0 0.3 0.3 0.0 0.1 1.4 0.0 0.2 0.4 0.8 0.3 0.0 0.2 2.1 0.1 2.1 0.2 0.2 1.3 0.5 0.0 14.0 1.2 0.0 0.3 0.1 0.0 0.8 1.1 0.2 0.8 0.0 0.0 3.2 0.0 0.6 6.4 0.0 0.0 1.4 0.0 1.3 0.1 1.6 1.4 0.0 0.0 1.6 1.6 0.1 0.0 0.0 18.9 0.0 0.8 7.1 8.4 8.4 9.4 7.5 7.3 8.3 7.8 8.0 9.8 7.6 12.9 2.6 0.0 3.0 24.2 2.3 0.0 2.9 0.0 2.8 6.5 3.8 5.2 1.0 0.0 0.6 1.8 18.8 0.5 11.4 10.8 0.0 1.7 233.2 1.7 1.5 2.6 1.2 0.0 45.4 1.4 0.4 4.8 7.7 0.3 0.0 2.0 1.8 0.1 1.2 6.7 27.3 1.4 0.0 0.6 0.0 855.9 6.2 2.8 0.0 44.0 1.7 12.2 0.0 23.6 86.0 1.5 5.2 7.5 1.0 1.5 0.8 3.1 2.2 7.9 6.6 2.9 2.7 22.2 5.8 0.5 0.0 0.3 3.3 2.1 3.3 1.0 BABAM2 "BRCC4, BRCC45, BRE" ENSG00000158019 "BRISC and BRCA1 A complex member 2" Q9NXR7 2 27889941-28338901 "Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Ubl conjugation pathway" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "adrenal gland: 380.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 46.1;Distal tubular cells: 84.1;Ductal cells: 53.4;Proximal tubular cells: 84.1;Syncytiotrophoblasts: 48.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017926, HPA048867" Enhanced Supported Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA017926: AB_1845443, HPA048867: " "unprognostic (1.28e-1)" "unprognostic (2.30e-1)" "unprognostic (1.53e-3)" "unprognostic (1.61e-3)" "unprognostic (1.89e-1)" "unprognostic (2.68e-3)" "prognostic unfavorable (6.33e-4)" "unprognostic (1.03e-1)" "unprognostic (2.38e-2)" "unprognostic (8.98e-2)" "unprognostic (2.13e-1)" "unprognostic (6.52e-2)" "unprognostic (4.41e-3)" "unprognostic (1.02e-1)" "unprognostic (4.74e-2)" "unprognostic (2.91e-2)" "unprognostic (1.22e-2)" 30.9 380.0 22.1 21.2 25.2 41.6 27.5 22.9 28.4 31.8 24.6 27.2 18.3 32.1 33.5 24.5 31.0 32.0 54.2 27.4 28.4 54.2 28.6 24.9 20.5 22.4 23.4 36.3 21.7 35.1 32.8 23.3 30.9 24.9 26.2 26.2 20.5 29.0 73.8 25.9 23.0 36.9 18.6 28.6 25.2 27.2 21.1 21.4 24.0 54.8 26.3 31.2 25.3 21.6 39.5 42.8 33.6 35.7 42.4 56.5 33.2 19.4 49.0 36.0 37.2 36.5 39.4 44.4 64.1 47.3 28.9 25.7 27.7 50.9 52.5 37.8 37.1 53.2 17.5 40.9 61.3 28.1 41.5 139.0 43.6 50.3 51.9 45.1 38.7 41.0 27.7 47.3 50.7 33.3 32.8 34.2 25.7 51.4 27.8 29.9 53.6 42.9 104.2 20.4 22.0 35.0 23.0 39.9 40.3 33.9 28.6 36.5 31.7 34.1 45.2 31.7 27.1 53.5 55.8 57.7 63.5 75.6 36.4 106.3 65.6 27.8 57.9 53.1 64.6 50.6 48.7 55.3 86.3 37.6 45.7 43.6 34.3 59.0 55.3 34.4 62.2 56.9 22.1 25.2 22.9 28.4 27.4 28.4 22.4 23.4 30.9 18.6 21.1 21.6 26.7 3.2 19.6 0.0 7.0 0.0 0.0 0.0 0.0 0.0 16.0 18.0 0.0 0.0 5.6 40.5 0.0 46.1 19.0 0.0 84.1 53.4 0.0 22.6 17.4 10.0 0.0 0.0 0.0 44.3 36.8 11.0 0.0 32.5 31.5 23.1 0.0 0.0 38.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 25.8 0.0 0.0 0.0 0.0 20.2 0.0 0.0 4.0 0.0 0.0 84.1 8.7 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 48.2 9.7 44.5 0.0 0.0 BAG3 ENSG00000151929 "BAG cochaperone 3" O95817 10 119651380-119677819 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Apoptosis Chaperone "Cardiomyopathy, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 349.1;skeletal muscle: 514.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 882.2;Basal squamous epithelial cells: 414.9;Squamous epithelial cells: 370.2;Urothelial cells: 488.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 4.1" "Lineage enriched" "Detected in single" 6 "T-cells: 4.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018493, HPA020586" Enhanced Supported Cytosol NA NA 460000 "Cluster 32: T-cells - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "HPA018493: AB_1845257, HPA020586: AB_1845258" "unprognostic (1.18e-1)" "unprognostic (1.68e-1)" "unprognostic (2.12e-2)" "unprognostic (1.17e-1)" "unprognostic (2.82e-2)" "unprognostic (5.31e-3)" "unprognostic (4.51e-3)" "unprognostic (3.32e-2)" "unprognostic (1.98e-2)" "unprognostic (1.46e-2)" "unprognostic (1.30e-2)" "unprognostic (1.49e-1)" "unprognostic (2.18e-3)" "unprognostic (4.21e-2)" "unprognostic (1.34e-1)" "unprognostic (8.46e-2)" "unprognostic (3.03e-2)" 73.5 40.3 81.6 16.1 80.6 5.1 40.5 96.9 349.1 41.7 61.3 72.4 12.3 45.2 20.4 86.0 37.7 35.1 153.3 82.1 124.3 42.2 38.4 77.9 8.2 127.2 100.2 33.3 20.5 53.6 36.6 36.0 101.3 39.1 12.6 12.6 50.1 24.5 514.4 61.9 25.9 43.3 106.3 15.9 72.4 23.1 84.1 5.7 31.1 187.8 17.3 60.4 55.3 95.5 100.1 111.2 30.5 39.6 77.2 53.9 56.9 89.1 74.7 66.6 56.8 47.5 47.6 3.8 41.4 76.9 86.6 145.2 31.5 157.2 45.7 49.1 51.8 5.4 28.6 60.1 65.2 0.3 22.1 54.6 89.0 48.6 76.2 70.5 75.5 17.1 43.3 24.0 67.2 142.7 5.5 22.3 12.0 33.1 125.8 0.3 43.2 17.2 50.7 22.3 5.6 5.1 35.4 61.9 47.2 32.9 38.8 13.4 94.8 35.0 30.1 47.8 129.5 22.1 14.0 2.4 65.2 1.5 27.1 0.0 0.6 0.0 0.6 0.7 1.1 0.1 2.4 0.8 0.4 0.0 4.1 1.4 0.2 0.1 0.3 0.1 1.7 0.6 81.6 80.6 96.9 349.1 82.1 124.3 127.2 100.2 101.3 106.3 84.1 95.5 77.8 22.4 43.2 34.9 10.9 79.4 882.2 51.0 414.9 6.1 48.3 62.9 196.0 18.6 48.1 7.3 18.8 41.4 4.9 61.7 27.4 19.4 29.3 56.7 60.0 107.0 38.5 0.8 1.3 25.3 57.0 142.7 51.5 89.1 23.6 7.3 22.5 15.3 33.7 1.7 2.5 87.0 46.8 8.7 95.4 32.8 22.4 146.9 55.2 10.3 4.7 32.6 3.1 1.0 1.2 37.3 69.2 24.0 29.5 225.1 8.3 42.8 39.4 1.7 19.7 141.6 134.3 21.8 18.7 370.2 76.1 73.5 85.6 10.0 53.9 488.1 BBC3 "JFY1, PUMA" ENSG00000105327 "BCL2 binding component 3" "Q96PG8, Q9BXH1" 19 47220822-47232766 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 117.4;Basal squamous epithelial cells: 111.5;Prostatic glandular cells: 132.9;Suprabasal keratinocytes: 143.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 4.5;neutrophil: 3.4" "Lineage enriched" "Detected in single" 7 "granulocytes: 4.5" "Cell line enhanced" "Detected in many" "HHSteC: 28.4;NB-4: 34.9" "CAB007752, HPA070403" Approved Approved Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 24: NB-4 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB007752: AB_562336, HPA070403: " "unprognostic (4.39e-2)" "unprognostic (2.02e-1)" "unprognostic (1.34e-1)" "prognostic favorable (1.31e-4)" "unprognostic (2.95e-2)" "unprognostic (4.74e-2)" "unprognostic (1.41e-1)" "unprognostic (1.06e-1)" "unprognostic (1.93e-1)" "unprognostic (8.38e-3)" "unprognostic (7.21e-2)" "unprognostic (2.22e-1)" "unprognostic (2.66e-2)" "unprognostic (4.66e-3)" "unprognostic (5.06e-2)" "unprognostic (3.57e-1)" "prognostic favorable (2.62e-5)" 3.1 4.4 3.1 2.1 2.8 4.8 4.0 4.3 4.7 3.2 1.8 6.4 2.4 3.4 0.6 1.9 3.6 2.0 3.9 3.3 2.4 5.1 5.6 7.7 2.7 2.8 3.7 3.2 7.7 2.0 2.1 1.9 2.9 4.1 1.8 0.2 7.5 1.2 10.4 8.2 5.0 0.7 2.3 6.1 5.0 2.6 2.8 4.0 3.1 1.1 0.8 4.9 3.4 2.5 3.8 8.3 9.0 1.9 2.1 4.1 22.1 5.9 7.9 1.4 3.5 2.5 6.3 14.7 2.5 1.5 2.5 1.2 1.3 5.3 0.2 9.3 15.9 4.2 2.8 16.4 28.4 0.7 13.4 9.8 8.4 3.0 2.8 3.7 10.3 4.4 10.9 9.0 1.0 8.6 1.6 34.9 5.6 6.5 1.1 4.1 1.3 17.7 0.4 1.3 1.5 13.5 2.7 5.6 18.7 7.1 1.9 11.7 6.9 1.7 11.1 0.2 1.9 14.4 3.4 9.5 2.6 2.2 6.2 4.5 0.4 0.2 0.4 0.5 0.4 0.1 0.1 0.3 0.2 0.0 0.5 0.3 3.4 0.6 0.4 0.1 0.3 0.2 3.1 2.8 4.3 4.7 3.3 2.4 2.8 3.7 2.9 2.3 2.8 2.5 16.2 9.6 7.4 1.6 21.7 117.4 78.8 40.3 111.5 6.5 46.4 29.1 5.6 10.0 21.8 7.3 0.0 4.7 28.3 51.9 0.0 52.4 14.6 65.2 14.0 15.8 21.4 16.8 3.2 39.8 5.5 12.1 23.4 66.2 12.7 8.4 3.9 3.5 7.1 0.0 3.9 40.6 30.5 10.3 31.9 3.3 6.2 17.1 64.0 2.8 15.7 3.7 32.0 1.0 0.5 55.2 49.3 4.1 19.3 132.9 16.2 4.1 22.9 4.4 6.6 12.4 34.9 0.5 1.7 59.4 143.3 20.5 28.5 10.2 27.4 66.2 BBS4 ENSG00000140463 "Bardet-Biedl syndrome 4" Q96RK4 15 72686179-72738475 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Sensory transduction, Transport, Vision" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Mental retardation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 120.9;Rod photoreceptor cells: 89.9;Spermatocytes: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 62.3" "Low region specificity" "Detected in all" HPA039418 Approved Approved Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 18: U-2197 - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "HPA039418: AB_10672962" "unprognostic (3.47e-1)" "unprognostic (2.83e-1)" "unprognostic (1.35e-1)" "prognostic favorable (2.57e-4)" "unprognostic (3.54e-1)" "unprognostic (2.91e-1)" "unprognostic (8.76e-2)" "unprognostic (5.47e-2)" "unprognostic (5.70e-2)" "unprognostic (2.56e-1)" "unprognostic (3.22e-3)" "unprognostic (1.26e-1)" "unprognostic (5.15e-2)" "unprognostic (4.87e-2)" "unprognostic (1.56e-1)" "unprognostic (1.11e-1)" "unprognostic (3.05e-1)" 9.5 14.8 11.0 6.8 11.2 7.7 10.9 10.1 13.1 13.3 18.1 12.0 5.1 12.5 15.4 5.8 17.5 9.3 11.1 10.9 11.9 15.6 12.7 10.4 8.0 10.9 12.4 14.0 11.1 17.4 20.7 7.9 12.6 20.7 7.6 45.4 7.9 9.4 18.7 9.2 7.9 9.3 10.9 7.6 11.0 20.4 11.5 11.5 16.1 10.2 7.0 11.1 9.1 11.0 6.1 15.7 34.0 14.4 16.5 19.7 9.0 11.9 24.4 11.3 14.8 8.1 20.2 9.6 24.7 10.2 8.6 9.4 9.1 9.9 10.3 10.0 11.0 11.4 13.3 9.2 13.5 10.2 8.6 18.8 13.2 16.3 12.8 17.1 8.9 18.3 25.4 8.2 18.1 10.7 9.6 9.6 48.8 12.3 6.8 6.4 17.1 12.3 19.2 15.2 16.4 19.2 20.8 15.0 31.2 13.1 20.4 11.3 12.5 13.2 10.0 62.3 6.7 17.1 17.8 21.0 14.9 15.3 18.1 5.5 1.9 3.3 5.1 2.9 4.9 4.8 4.3 5.5 1.6 6.0 4.3 5.9 1.6 11.0 2.5 3.1 5.7 2.8 11.0 11.2 10.1 13.1 10.9 11.9 10.9 12.4 12.6 10.9 11.5 11.0 6.0 19.2 19.2 35.3 8.3 3.1 6.0 9.4 10.8 39.0 8.4 10.5 19.8 4.3 18.2 12.9 120.9 10.0 10.6 3.5 5.9 14.4 19.9 28.8 11.1 8.1 4.2 5.2 18.6 11.3 5.8 12.4 7.7 8.4 13.9 8.7 7.1 7.4 7.8 21.9 22.8 8.0 6.1 5.8 2.4 12.2 15.8 5.9 5.4 19.7 4.4 39.4 9.2 31.7 30.7 8.9 4.9 20.3 9.0 8.0 5.1 9.4 48.8 89.9 0.0 11.0 11.5 79.0 63.6 4.6 2.8 5.3 9.3 24.3 5.1 2.8 BCAP29 "BAP29, DKFZp686M2086" ENSG00000075790 "B cell receptor associated protein 29" Q9UHQ4 7 107580246-107629170 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029215, HPA049694" Supported Approved Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "HPA029215: AB_10602331, HPA049694: AB_2680854" "unprognostic (3.96e-2)" "unprognostic (9.94e-2)" "unprognostic (1.82e-2)" "unprognostic (1.05e-2)" "unprognostic (5.42e-3)" "unprognostic (4.71e-3)" "prognostic unfavorable (3.62e-4)" "unprognostic (6.43e-2)" "unprognostic (7.22e-2)" "unprognostic (9.64e-2)" "unprognostic (2.31e-2)" "unprognostic (7.36e-2)" "unprognostic (8.34e-2)" "unprognostic (5.40e-2)" "unprognostic (2.78e-2)" "unprognostic (5.28e-3)" "unprognostic (1.81e-1)" 47.1 25.7 19.4 22.5 23.7 16.7 28.0 18.1 27.0 48.6 12.8 32.6 16.1 42.6 18.6 34.4 21.7 23.0 61.0 24.4 17.9 20.1 33.3 26.0 16.7 17.5 17.6 21.4 18.9 34.5 12.2 26.7 18.0 31.9 31.2 9.6 18.4 25.0 38.7 22.1 18.8 38.2 19.5 18.1 22.4 70.1 19.2 12.8 85.5 31.5 15.7 30.9 32.5 21.1 71.7 22.8 26.4 13.8 65.2 81.6 22.6 80.6 68.2 32.9 39.7 23.2 72.1 13.4 54.5 58.1 75.1 35.8 13.7 38.6 52.5 50.1 17.3 27.1 35.6 26.2 63.3 33.6 41.2 48.9 31.8 46.7 38.0 95.4 116.9 25.3 58.3 33.4 75.4 67.2 23.2 34.3 15.4 29.7 30.0 18.6 34.1 34.6 60.6 49.1 10.2 37.7 68.2 54.9 58.2 39.3 25.6 37.5 113.9 102.5 52.1 94.6 104.7 31.7 67.9 27.5 66.5 30.5 77.2 47.5 10.5 25.5 9.5 13.6 9.3 12.8 7.5 9.5 10.0 8.5 4.3 8.5 3.9 9.9 21.7 10.1 13.6 8.1 19.4 23.7 18.1 27.0 24.4 17.9 17.5 17.6 18.0 19.5 19.2 21.1 169.8 67.3 57.2 35.6 33.9 38.5 80.7 99.0 25.0 35.2 40.4 34.2 117.8 27.1 77.7 23.9 10.4 30.2 31.4 38.1 15.6 46.4 227.1 54.6 93.3 99.0 22.3 73.2 81.1 73.6 50.8 72.9 32.6 102.0 58.3 14.8 73.2 40.7 52.6 8.4 71.3 35.8 69.2 36.6 35.6 95.8 61.2 49.6 37.4 44.0 41.6 28.3 22.6 50.8 49.7 71.2 32.5 89.1 17.7 110.4 15.6 19.5 55.9 26.7 78.9 62.9 91.3 202.2 35.0 46.5 38.8 70.7 33.5 32.0 45.4 83.5 BCL2L14 "BCL-G, BCLG" ENSG00000121380 "BCL2 like 14" Q9BZR8 12 12049844-12211084 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 15.5;stomach 1: 9.4;testis: 31.4" "Group enriched" "Detected in many" 6 "Early spermatids: 385.6;Late spermatids: 863.1" "Group enriched" "Detected in many" 4 "colorectal cancer: 5.2;pancreatic cancer: 1.8;stomach cancer: 3.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.1;NTERA-2: 1.6;OE19: 2.0;RT4: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA040665, HPA059846" Enhanced Uncertain Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA040665: AB_10964282, HPA059846: " "unprognostic (3.65e-4)" "unprognostic (4.95e-3)" "unprognostic (1.68e-2)" "unprognostic (2.02e-3)" "unprognostic (2.69e-1)" "unprognostic (2.70e-4)" "unprognostic (1.10e-1)" "unprognostic (2.43e-1)" "unprognostic (3.24e-2)" "unprognostic (4.59e-5)" "unprognostic (1.06e-2)" "unprognostic (1.06e-2)" "unprognostic (5.79e-6)" "unprognostic (3.83e-2)" "unprognostic (3.37e-2)" "unprognostic (2.82e-2)" "unprognostic (1.73e-8)" 0.0 0.0 0.1 2.5 0.1 0.1 0.5 0.0 0.1 0.2 0.1 10.7 13.7 0.1 0.1 0.2 0.1 1.2 0.0 0.2 0.0 0.1 0.5 0.4 1.3 0.1 0.0 0.0 5.3 0.0 0.0 0.0 0.0 1.1 15.5 0.0 0.9 0.0 0.0 0.0 12.9 0.4 0.0 0.7 9.4 31.4 0.0 1.2 0.0 0.0 0.8 1.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 2.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 2.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 2.3 1.6 0.2 0.4 2.9 3.2 0.0 0.3 2.5 1.3 0.7 2.8 4.5 1.8 0.0 0.1 0.2 30.1 0.0 0.3 385.6 1.2 0.2 0.7 6.7 0.0 2.1 7.5 0.0 0.5 28.5 0.8 0.0 0.1 0.0 0.3 0.2 0.0 1.4 45.0 2.0 0.3 3.8 863.1 5.6 0.9 0.0 0.0 3.8 0.1 0.0 1.5 1.1 2.6 22.9 3.8 0.5 4.0 95.0 0.0 5.0 1.0 6.6 1.2 0.6 6.5 2.8 0.0 0.4 0.1 0.6 0.1 30.6 9.4 BDH2 "DHRS6, FLJ13261, PRO20933, SDR15C1, UCPA-OR, UNQ6308" ENSG00000164039 "3-hydroxybutyrate dehydrogenase 2" Q9BUT1 4 103077592-103099870 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 162.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 211.3;Proximal tubular cells: 795.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 46.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036028, HPA036029" Enhanced Supported Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA036028: AB_10670674, HPA036029: AB_2674909" "unprognostic (2.12e-2)" "unprognostic (1.91e-1)" "unprognostic (1.64e-1)" "prognostic favorable (5.21e-4)" "unprognostic (3.92e-1)" "unprognostic (2.28e-1)" "unprognostic (3.82e-2)" "prognostic favorable (1.20e-4)" "unprognostic (1.71e-1)" "unprognostic (2.04e-1)" "unprognostic (4.37e-1)" "unprognostic (1.95e-1)" "prognostic favorable (4.45e-13)" "unprognostic (2.54e-2)" "unprognostic (1.60e-1)" "prognostic favorable (7.75e-4)" "unprognostic (9.69e-3)" 45.0 96.6 23.3 4.3 25.8 3.5 39.7 27.0 27.3 46.6 27.1 31.8 39.4 31.2 16.6 27.2 43.4 14.9 46.6 20.3 27.8 162.1 70.5 35.9 6.7 28.4 26.5 54.8 23.2 30.8 29.2 7.7 27.0 31.9 10.3 8.5 32.8 14.1 24.6 26.1 39.6 9.6 25.2 21.2 38.9 14.8 28.2 17.5 62.9 16.7 7.3 37.1 37.3 26.5 3.1 5.3 26.5 10.0 30.4 29.4 3.4 6.7 17.8 6.9 10.6 3.4 11.8 12.4 11.1 10.2 2.1 1.5 17.3 10.1 8.2 8.2 8.5 1.5 6.4 8.1 15.0 7.4 2.1 24.8 9.1 10.6 2.6 23.0 20.7 14.3 8.0 5.5 24.1 1.0 37.2 6.3 9.6 2.0 2.1 24.5 30.7 7.9 46.4 3.6 4.5 12.0 12.8 6.7 7.9 9.6 5.7 5.3 9.9 10.7 3.4 5.5 3.7 8.1 7.9 12.5 11.8 8.9 5.4 2.6 2.5 0.2 7.6 1.4 8.8 4.8 6.6 6.0 3.2 6.7 9.8 10.4 0.4 6.5 0.2 5.0 10.2 4.0 23.3 25.8 27.0 27.3 20.3 27.8 28.4 26.5 27.0 25.2 28.2 26.5 37.7 32.1 57.8 33.6 10.2 30.3 47.1 59.4 36.5 2.5 31.9 36.1 9.6 64.3 46.9 108.5 0.0 7.9 19.0 18.0 211.3 58.2 1.9 60.6 45.5 30.3 22.9 16.4 1.2 21.3 18.5 75.2 41.8 27.9 19.6 39.1 27.8 71.6 20.4 3.3 3.8 24.4 46.8 10.9 16.9 4.8 69.9 12.5 23.2 14.0 14.9 50.4 14.4 3.5 21.8 23.0 18.6 77.8 8.0 18.9 162.3 795.7 48.7 3.8 13.1 40.9 36.5 0.9 4.0 25.9 26.7 3.4 18.2 52.6 37.6 37.5 BEX1 ENSG00000133169 "Brain expressed X-linked 1" Q9HBH7 X 103062651-103064171 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 439.4;pituitary gland: 399.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 354.2;Granulosa cells: 260.7;Horizontal cells: 363.4;Muller glia cells: 716.1;Rod photoreceptor cells: 142.2" "Cancer enhanced" "Detected in many" "glioma: 111.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 607.0;HBF TERT88: 680.4;HL-60: 1562.2;hTERT-RPE1: 1044.5;SCLC-21H: 465.3;U-937: 484.1" "HPA045384, HPA078630" Approved Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 32: U-937 - Innate immune response" "Cluster 5: Muller glia cells - Visual perception" Cytosol "HPA045384: AB_2679305, HPA078630: " "prognostic favorable (6.43e-4)" "unprognostic (1.51e-1)" "unprognostic (8.92e-2)" "unprognostic (2.94e-2)" "unprognostic (1.66e-1)" "unprognostic (7.75e-2)" "unprognostic (2.27e-1)" "unprognostic (2.33e-1)" "unprognostic (2.11e-1)" "unprognostic (1.12e-2)" "unprognostic (5.28e-3)" "unprognostic (2.09e-1)" "prognostic favorable (8.16e-8)" "unprognostic (1.14e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (6.88e-4)" "unprognostic (7.34e-2)" 1.5 83.8 253.7 3.8 260.1 42.7 2.5 201.9 317.4 5.5 142.9 10.5 5.0 15.6 55.5 0.8 21.4 1.3 16.7 274.9 439.4 10.7 4.2 2.8 1.2 222.6 248.2 20.2 71.6 112.0 399.2 0.4 261.1 6.7 4.3 173.0 2.3 3.6 0.6 1.0 6.3 4.8 203.1 2.5 8.6 92.9 265.5 3.5 26.0 0.8 0.4 0.8 2.9 223.9 0.7 0.0 37.6 0.1 0.0 0.1 1.1 21.6 0.0 412.1 607.0 0.0 0.1 0.1 0.8 158.1 130.0 0.4 0.0 0.5 680.4 0.2 1.2 129.2 0.0 85.2 6.9 1562.2 2.6 9.2 0.0 89.3 0.1 1044.5 0.1 120.8 0.2 0.2 84.6 0.0 294.7 0.2 337.9 97.8 62.0 0.2 0.7 7.6 0.0 0.3 465.3 266.6 0.5 0.6 1.9 5.9 0.3 432.4 0.0 0.1 140.2 1.1 16.7 71.9 2.9 0.7 54.4 484.1 27.2 0.4 0.2 3.4 0.3 0.0 0.3 0.5 0.9 0.5 0.0 1.0 1.4 0.6 0.5 0.9 0.2 0.1 0.4 0.7 253.7 260.1 201.9 317.4 274.9 439.4 222.6 248.2 261.1 203.1 265.5 223.9 1.1 0.0 0.5 16.3 1.2 8.7 11.1 0.0 1.2 354.2 7.2 32.5 9.6 31.5 0.7 5.5 39.6 0.2 0.2 0.4 72.4 6.1 12.1 1.4 0.6 5.3 79.6 0.8 64.6 13.8 0.2 3.9 8.2 2.8 0.0 260.7 30.4 1.2 1.4 363.4 56.1 6.9 10.2 4.0 1.2 31.8 8.1 2.2 7.2 12.2 1.5 716.1 0.0 32.6 20.9 6.3 3.3 2.6 0.0 7.5 0.8 19.5 0.0 142.2 0.0 15.9 14.4 38.5 13.8 0.0 6.5 0.5 2.0 0.2 3.5 1.7 BEX2 DJ79P11.1 ENSG00000133134 "Brain expressed X-linked 2" Q9BXY8 X 103309346-103311007 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 194.6" "Cell type enhanced" "Detected in many" "Distal tubular cells: 418.7;Muller glia cells: 285.9;Proximal tubular cells: 201.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 52.7;NK-cells: 62.0;T-cells: 68.6" "Cell line enhanced" "Detected in many" "hTCEpi: 94.7;NTERA-2: 91.4;SCLC-21H: 135.2;SH-SY5Y: 61.4" "HPA045384, HPA078630" Uncertain Uncertain Cytosol NA NA "Cluster 30: Non-specific - Translation" "Cluster 68: Epididymis - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA045384: AB_2679305, HPA078630: " "unprognostic (7.56e-2)" "unprognostic (7.08e-2)" "unprognostic (3.46e-2)" "prognostic unfavorable (8.54e-7)" "unprognostic (3.21e-1)" "unprognostic (1.65e-1)" "unprognostic (4.27e-2)" "prognostic favorable (1.52e-4)" "unprognostic (7.36e-3)" "unprognostic (6.82e-2)" "unprognostic (8.22e-3)" "unprognostic (6.63e-2)" "prognostic favorable (3.05e-13)" "unprognostic (4.14e-3)" "unprognostic (6.80e-2)" "unprognostic (1.40e-1)" "unprognostic (2.38e-3)" 5.8 73.6 133.5 6.8 134.9 13.7 19.4 119.0 167.3 16.4 98.2 10.2 3.4 27.6 123.8 9.9 15.5 7.6 29.5 134.4 153.2 58.7 2.5 12.7 14.2 120.7 125.6 62.8 35.5 123.1 194.6 8.0 123.7 24.2 6.0 83.5 26.7 21.0 9.1 17.1 14.0 8.7 117.7 18.5 16.7 43.1 138.6 21.0 103.3 11.5 16.9 8.7 10.7 132.2 0.0 2.8 11.3 0.1 0.2 0.0 45.5 0.3 6.1 7.7 11.3 8.4 3.8 0.0 31.6 0.0 55.4 2.0 0.1 9.4 6.6 0.1 25.4 1.4 1.4 0.4 46.0 0.1 25.4 2.8 94.7 3.7 29.1 17.8 0.5 33.6 17.4 0.7 1.0 4.2 20.1 0.2 91.4 0.0 8.4 0.1 0.0 0.2 3.8 3.7 135.2 61.4 5.9 1.4 22.2 10.7 11.2 0.1 0.0 0.1 9.0 0.3 2.1 30.8 21.6 0.1 15.3 0.0 1.3 13.4 0.4 1.1 21.8 0.4 31.0 52.7 43.8 25.7 1.6 42.3 68.6 50.0 1.4 62.0 0.1 10.0 33.7 18.4 133.5 134.9 119.0 167.3 134.4 153.2 120.7 125.6 123.7 117.7 138.6 132.2 3.7 16.0 68.5 15.0 41.6 31.6 95.6 17.4 100.7 184.7 65.8 145.5 27.0 60.1 43.4 114.0 43.8 72.2 20.9 5.0 418.7 47.5 17.9 11.6 3.3 13.7 100.5 9.4 56.7 42.7 19.9 13.1 23.0 17.0 12.7 87.6 3.6 0.9 7.0 121.1 53.0 29.6 16.2 0.3 5.3 69.4 15.8 4.6 26.6 7.5 2.5 285.9 27.8 35.2 25.8 19.8 8.4 22.2 16.5 64.5 3.7 201.3 9.0 120.5 6.6 32.0 11.4 16.8 5.8 25.7 26.7 63.8 30.2 22.3 22.3 51.1 BEX3 "Bex, DXS6984E, HGR74, NADE, NGFRAP1" ENSG00000166681 "Brain expressed X-linked 3" Q00994 X 103376395-103378164 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1607.8;Distal tubular cells: 1453.7;Granulosa cells: 700.3;Proximal tubular cells: 688.0;Syncytiotrophoblasts: 804.2;Theca cells: 696.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 150.9;T-reg: 137.1" "Lineage enriched" "Detected in all" 5 "T-cells: 150.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018886 Approved Supported Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 68: Epididymis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA018886: AB_1854453" "unprognostic (7.74e-2)" "unprognostic (6.56e-2)" "unprognostic (8.15e-3)" "prognostic unfavorable (7.23e-5)" "unprognostic (2.70e-1)" "unprognostic (1.93e-3)" "unprognostic (7.15e-2)" "unprognostic (2.19e-1)" "unprognostic (1.79e-1)" "unprognostic (1.10e-2)" "unprognostic (3.85e-3)" "unprognostic (2.00e-1)" "prognostic favorable (1.28e-4)" "prognostic unfavorable (3.48e-4)" "unprognostic (1.38e-1)" "unprognostic (3.32e-2)" "unprognostic (8.68e-2)" 106.8 345.8 382.4 39.6 395.3 31.1 111.0 353.0 432.9 144.6 462.7 123.4 31.2 149.1 499.4 72.8 150.9 77.1 244.7 401.5 491.6 263.6 92.8 116.8 29.3 368.8 392.1 463.7 120.0 231.1 373.7 207.0 384.1 166.7 53.0 135.9 99.5 224.9 19.8 61.6 56.3 116.5 364.9 97.3 94.6 139.9 419.3 97.0 274.6 44.5 28.4 107.8 104.6 365.7 218.5 305.3 561.5 222.3 508.5 567.3 256.6 244.7 409.8 299.5 475.0 317.9 238.1 0.3 427.8 288.7 222.0 85.3 394.1 302.5 299.4 0.8 280.6 98.7 502.9 87.4 396.2 0.8 37.4 613.4 252.2 397.3 348.0 533.6 469.5 225.0 0.1 1.0 542.2 486.1 227.2 2.7 750.5 0.1 232.3 0.4 350.3 0.5 317.9 365.3 377.3 391.4 264.7 3.2 380.3 359.8 142.4 31.8 291.5 191.6 123.3 374.6 110.0 2.2 1.0 1.6 395.3 0.3 189.1 0.3 3.7 1.1 4.1 0.9 2.2 4.6 71.8 19.1 6.4 1.2 150.9 70.8 13.9 28.9 0.8 14.5 137.1 66.5 382.4 395.3 353.0 432.9 401.5 491.6 368.8 392.1 384.1 364.9 419.3 365.7 118.5 326.9 227.7 0.0 12.6 0.0 0.0 0.0 0.0 0.0 217.4 433.2 0.0 0.0 104.0 518.6 0.0 1607.8 4.7 0.0 1453.7 201.3 0.0 187.0 284.8 132.3 0.0 0.0 0.0 70.9 471.7 189.2 0.0 144.1 16.4 700.3 0.0 0.0 172.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 0.0 0.0 2.0 0.0 0.0 0.0 0.0 49.0 0.0 0.0 1.7 0.0 0.0 688.0 23.3 0.0 0.0 0.0 117.8 0.0 0.0 0.0 0.0 804.2 12.8 696.8 0.0 0.0 BHMT BHMT1 ENSG00000145692 "Betaine--homocysteine S-methyltransferase" Q93088 5 79111809-79132288 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 83 "kidney: 778.9;liver: 1141.8" "Group enriched" "Detected in some" 10 "Hepatocytes: 604.2;Proximal tubular cells: 996.1" "Group enriched" "Detected in some" 4 "liver cancer: 90.6;renal cancer: 50.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 3.6;NTERA-2: 1.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA038285, HPA058310" Enhanced Supported Cytosol No NA 10000000 "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA038285: AB_10675791, HPA058310: AB_2683675" "unprognostic (2.61e-2)" "unprognostic (4.12e-1)" "unprognostic (4.45e-1)" "unprognostic (4.14e-3)" "unprognostic (5.62e-2)" "unprognostic (4.14e-1)" "prognostic favorable (7.32e-4)" "unprognostic (5.33e-2)" "unprognostic (1.51e-1)" "unprognostic (1.13e-1)" "unprognostic (9.66e-4)" "unprognostic (6.42e-2)" "unprognostic (8.26e-3)" "unprognostic (1.77e-1)" "unprognostic (3.22e-1)" "unprognostic (3.60e-2)" "unprognostic (2.30e-3)" 0.7 0.3 0.3 0.0 0.8 0.0 0.5 0.0 0.5 0.3 0.1 0.6 1.2 0.2 1.8 0.1 0.2 0.2 0.2 0.5 0.3 778.9 1141.8 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.5 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.1 3.2 0.3 0.3 0.5 0.4 0.0 0.0 11.6 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.6 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.5 0.5 0.3 0.1 0.2 0.1 0.1 0.3 0.2 0.1 0.0 0.0 1.0 5.2 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.3 4.3 0.0 16.5 0.0 0.0 0.0 0.0 78.2 0.0 0.5 0.1 0.8 0.8 0.0 13.5 0.9 0.0 0.1 0.1 8.2 0.2 0.0 0.1 8.9 604.2 0.0 0.0 0.2 0.4 0.0 12.2 0.0 0.5 0.9 3.5 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 2.6 0.0 0.0 0.0 996.1 0.0 0.4 0.0 0.2 0.1 0.2 1.0 0.0 0.0 0.1 4.2 0.5 0.1 0.3 BID ENSG00000015475 "BH3 interacting domain death agonist" P55957 22 17734138-17774770 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 103.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 273.2;Langerhans cells: 658.8;monocytes: 491.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 6 "dendritic cells: 345.8;granulocytes: 925.5;monocytes: 985.3" "Cell line enhanced" "Detected in all" "MCF7: 241.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000722, CAB003771" Enhanced Supported Cytosol NA NA 800000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 3: Monocytes - Immune response regulation" Cytosol "CAB003771: AB_365478, HPA000722: AB_1078283" "unprognostic (1.59e-1)" "unprognostic (5.51e-2)" "unprognostic (5.02e-2)" "unprognostic (3.04e-2)" "unprognostic (4.27e-3)" "unprognostic (1.11e-2)" "unprognostic (3.84e-2)" "unprognostic (5.21e-3)" "unprognostic (1.44e-2)" "unprognostic (1.53e-1)" "unprognostic (1.12e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (3.50e-13)" "unprognostic (4.66e-3)" "unprognostic (1.59e-1)" "unprognostic (3.55e-3)" "unprognostic (2.18e-2)" 13.6 6.9 19.4 30.5 20.9 103.5 10.7 19.2 22.4 6.0 12.8 14.7 15.1 5.7 7.2 7.5 6.2 14.7 17.4 20.0 19.5 10.0 28.2 12.0 35.6 19.9 19.8 5.7 9.5 3.5 6.4 7.9 20.8 8.1 11.0 36.9 8.1 4.1 23.3 7.6 17.5 6.8 20.1 30.0 12.2 3.6 22.0 26.4 5.8 7.8 16.7 34.4 7.5 20.2 117.5 90.6 14.4 43.7 15.2 27.7 20.4 59.1 45.4 44.8 38.4 55.4 67.2 22.8 41.5 25.7 52.3 97.8 14.5 14.7 24.7 37.0 73.4 101.3 39.7 81.3 19.1 110.4 107.0 26.7 31.4 49.8 11.3 35.6 46.8 64.8 84.0 27.2 23.0 241.6 161.0 148.2 47.2 130.2 62.8 76.6 37.3 32.8 12.0 141.2 91.3 65.9 12.5 38.2 37.1 6.2 80.3 132.9 80.4 26.0 36.0 43.9 46.7 39.8 57.2 75.7 74.6 113.0 33.8 156.9 417.0 691.4 82.1 748.3 81.7 53.0 75.8 92.5 345.8 33.0 61.2 72.2 925.5 124.1 985.3 245.8 108.0 428.1 19.4 20.9 19.2 22.4 20.0 19.5 19.9 19.8 20.8 20.1 22.0 20.2 49.0 16.0 14.5 16.0 34.5 71.9 53.1 273.2 21.1 3.0 30.0 30.5 17.5 17.2 142.6 9.2 2.1 9.3 70.3 25.1 7.9 67.9 0.6 10.5 14.5 47.4 34.1 23.3 17.6 51.4 5.6 24.9 13.7 11.4 25.3 34.3 23.2 44.0 134.1 0.0 15.6 38.7 63.1 69.1 658.8 1.6 5.3 164.2 58.7 13.1 491.3 3.0 65.9 4.5 2.1 78.5 85.1 4.1 45.2 186.4 16.5 28.6 59.7 1.7 0.0 12.0 24.3 1.3 11.9 13.2 64.5 5.1 38.3 13.6 49.8 213.0 BIN1 "AMPH2, AMPHL, SH3P9" ENSG00000136717 "Bridging integrator 1" O00499 2 127048027-127107288 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Endocytosis, Host-virus interaction" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 2105.3;tongue: 803.2" "Cell type enhanced" "Detected in all" "Hofbauer cells: 164.9;NK-cells: 176.1;Oligodendrocytes: 186.4;Proximal tubular cells: 255.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "gdT-cell: 186.6;MAIT T-cell: 163.9;memory B-cell: 165.9;memory CD4 T-cell: 192.1;memory CD8 T-cell: 187.4;naive B-cell: 181.2;naive CD4 T-cell: 177.1;naive CD8 T-cell: 171.1;NK-cell: 178.9;T-reg: 249.8" "Group enriched" "Detected in all" 9 "B-cells: 181.2;NK-cells: 178.9;T-cells: 249.8" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 126.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001945, HPA003894, HPA005437" Enhanced Supported Cytosol NA NA 430000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 37: Myocytes - Muscle contraction" Cytosol "CAB001945: , HPA003894: AB_1845360, HPA005437: AB_1078284" "unprognostic (2.20e-2)" "unprognostic (1.61e-1)" "unprognostic (2.65e-2)" "unprognostic (9.65e-2)" "unprognostic (1.55e-1)" "unprognostic (1.08e-1)" "unprognostic (3.06e-2)" "unprognostic (2.21e-1)" "unprognostic (3.52e-1)" "unprognostic (1.55e-1)" "unprognostic (1.02e-3)" "unprognostic (1.85e-1)" "unprognostic (1.42e-3)" "unprognostic (1.26e-2)" "unprognostic (2.57e-1)" "unprognostic (2.41e-3)" "unprognostic (3.22e-3)" 43.7 93.2 178.8 25.7 232.8 12.0 37.3 162.6 209.6 53.8 85.9 35.2 17.4 38.7 16.8 33.5 53.5 22.6 16.5 174.2 160.6 83.4 34.7 22.7 41.0 204.2 194.8 34.4 21.5 19.6 41.0 23.5 189.8 58.1 13.1 53.7 42.6 24.0 2105.3 14.8 31.5 19.6 155.4 54.7 45.0 10.4 199.2 18.4 28.5 803.2 27.5 89.0 36.6 310.5 52.0 27.9 32.8 39.3 95.9 76.5 11.4 15.3 33.1 35.8 23.4 107.6 31.3 0.0 46.0 28.9 20.8 6.8 14.6 25.0 9.5 5.9 4.1 15.1 46.9 7.1 86.2 0.2 2.8 70.2 6.1 77.3 14.0 46.4 49.1 5.1 3.2 1.6 44.8 1.1 4.9 43.3 24.8 114.2 31.4 11.8 36.3 4.8 126.7 0.1 22.4 61.9 55.5 21.2 17.7 34.7 1.3 9.7 59.3 40.9 39.9 52.8 52.1 1.3 1.4 0.3 60.3 2.6 19.2 1.2 3.1 0.6 186.6 2.0 163.9 165.9 192.1 187.4 15.1 181.2 177.1 171.1 6.0 178.9 3.2 21.5 249.8 133.5 178.8 232.8 162.6 209.6 174.2 160.6 204.2 194.8 189.8 155.4 199.2 310.5 15.6 9.6 10.0 10.7 80.1 18.6 10.0 3.3 1.2 144.1 10.7 9.1 5.6 44.3 5.5 14.7 125.1 1.8 98.3 18.6 37.2 15.2 16.1 11.7 46.2 21.9 46.0 11.6 36.9 29.4 4.2 68.7 29.0 19.0 2.5 28.7 15.0 18.3 164.9 30.3 47.2 28.0 10.2 27.0 62.3 55.8 78.6 50.1 23.2 58.1 10.4 25.3 176.1 11.6 186.4 16.7 18.1 30.5 14.6 26.2 14.3 255.7 1.4 133.4 13.1 75.7 28.8 2.6 10.9 1.6 8.9 2.9 98.2 40.0 50.1 9.8 BLVRA BLVR ENSG00000106605 "Biliverdin reductase A" P53004 7 43758680-43807342 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 259.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019709, HPA042865, HPA054322" Approved Supported Cytosol NA NA 1200000 "Cluster 7: Monocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "HPA019709: AB_2670239, HPA042865: AB_10797024, HPA054322: AB_2682450" "unprognostic (2.47e-2)" "unprognostic (8.38e-3)" "unprognostic (1.79e-2)" "unprognostic (2.16e-3)" "unprognostic (6.45e-3)" "unprognostic (5.01e-2)" "unprognostic (1.63e-2)" "prognostic favorable (8.65e-4)" "unprognostic (1.42e-1)" "unprognostic (1.75e-2)" "unprognostic (2.93e-1)" "unprognostic (9.27e-2)" "unprognostic (1.15e-2)" "unprognostic (5.63e-3)" "unprognostic (3.18e-1)" "unprognostic (2.13e-3)" "unprognostic (4.56e-2)" 53.2 28.0 31.4 39.7 33.4 65.6 49.9 32.0 40.1 44.3 31.4 61.4 12.5 38.5 129.9 67.5 40.9 33.4 52.7 32.3 34.7 41.3 14.6 62.7 58.6 34.1 33.6 46.6 23.5 54.9 26.2 28.9 34.2 38.4 19.8 25.4 36.5 46.0 59.7 33.4 27.7 54.1 33.1 82.0 35.3 13.1 34.0 43.0 31.3 69.3 52.6 43.5 40.4 32.0 48.6 92.2 26.2 110.5 55.0 72.7 1.3 32.3 99.3 54.0 65.4 22.2 28.3 0.3 60.6 51.5 190.7 62.1 82.1 81.7 46.2 227.3 56.8 104.1 86.6 138.1 139.5 11.8 37.5 49.9 135.7 57.2 37.8 108.5 92.7 51.1 70.2 55.7 41.4 52.5 37.0 6.3 35.9 11.0 104.7 80.4 45.6 261.4 121.1 26.6 34.0 104.4 65.9 65.1 55.2 46.2 146.7 77.7 57.0 49.3 53.9 21.8 56.0 74.7 63.2 0.2 80.8 46.9 78.4 51.1 291.9 169.2 39.1 374.9 36.7 26.9 75.7 64.9 135.4 17.0 39.7 31.0 26.5 22.4 368.4 20.1 82.2 208.5 31.4 33.4 32.0 40.1 32.3 34.7 34.1 33.6 34.2 33.1 34.0 32.0 22.0 60.9 85.0 7.5 10.7 29.1 64.2 102.4 34.1 18.0 29.6 36.1 59.4 17.2 75.7 35.0 2.1 9.7 9.3 0.3 56.7 52.6 0.7 31.6 20.2 27.3 0.0 74.7 8.4 35.1 8.1 39.7 8.2 41.4 111.5 17.2 24.3 1.9 259.1 8.4 11.5 0.4 59.0 136.5 53.7 1.6 37.0 80.4 46.2 2.8 147.3 36.6 13.4 7.5 4.3 25.2 1.2 29.0 16.6 87.9 7.1 110.5 69.6 13.0 46.0 23.0 50.6 3.0 14.2 52.9 34.4 5.2 23.4 4.9 0.6 48.7 BMPR1A "ACVRLK3, ALK3, CD292" ENSG00000107779 "Bone morphogenetic protein receptor type 1A" P36894 10 86756601-86932825 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 142.7;Inhibitory neurons: 79.9;Oligodendrocyte precursor cells: 122.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB019398 Approved Approved Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "CAB019398: " "unprognostic (1.36e-1)" "unprognostic (2.46e-1)" "unprognostic (3.34e-1)" "unprognostic (9.61e-2)" "unprognostic (1.05e-3)" "unprognostic (9.34e-2)" "prognostic unfavorable (8.93e-4)" "unprognostic (3.64e-1)" "unprognostic (2.38e-2)" "unprognostic (1.53e-1)" "unprognostic (9.24e-2)" "unprognostic (9.42e-2)" "unprognostic (4.32e-2)" "unprognostic (1.80e-1)" "unprognostic (1.47e-1)" "unprognostic (1.01e-2)" "unprognostic (1.07e-1)" 9.1 6.4 4.3 4.5 5.2 0.0 10.3 5.4 5.5 8.1 4.9 9.9 5.4 12.9 11.9 7.8 7.4 9.6 7.8 4.7 6.1 7.0 4.3 7.3 2.9 6.8 5.8 11.6 5.8 9.9 2.6 6.5 6.3 12.5 8.2 4.8 12.1 13.0 7.9 9.3 8.6 12.5 6.2 2.9 7.3 5.2 4.6 2.9 19.1 4.8 3.0 7.9 4.1 6.5 14.6 7.8 27.6 26.8 15.0 10.6 5.5 14.5 18.3 9.4 11.3 11.0 13.1 4.7 6.1 19.2 5.9 15.0 15.8 14.3 14.1 5.5 8.2 5.9 6.9 19.0 10.2 7.4 37.7 10.7 8.5 11.2 9.5 13.9 0.0 8.1 7.6 2.7 12.3 7.0 6.7 7.8 17.6 5.2 4.2 0.0 12.3 0.1 18.9 12.1 3.7 12.8 17.8 8.4 12.6 34.1 15.0 4.1 6.2 7.0 9.8 12.7 13.3 0.3 12.3 5.3 6.5 5.6 6.0 0.3 0.0 0.0 0.3 0.0 0.2 0.3 0.2 0.2 0.0 0.1 0.1 0.2 0.2 0.1 0.0 0.1 0.1 0.0 4.3 5.2 5.4 5.5 4.7 6.1 6.8 5.8 6.3 6.2 4.6 6.5 3.5 35.3 22.4 142.7 3.5 12.1 7.1 9.9 17.6 7.5 10.2 10.2 22.6 18.6 10.5 11.0 20.9 14.1 2.3 10.7 1.9 10.6 0.7 10.7 19.7 4.5 18.0 0.0 63.8 9.5 1.0 20.6 19.4 13.9 15.2 22.9 9.3 7.2 3.4 11.8 79.9 13.9 8.2 4.8 6.1 4.1 33.5 2.3 8.8 34.7 0.8 12.9 2.1 122.2 64.3 8.9 4.9 31.2 3.2 13.7 10.6 5.5 16.5 20.4 6.6 20.3 19.2 2.1 6.6 11.5 9.8 5.1 4.3 11.9 11.1 6.7 BMT2 "C7orf60, DKFZp762M126, FLJ31818, SAMTOR" ENSG00000164603 "Base methyltransferase of 25S rRNA 2 homolog" Q1RMZ1 7 112819147-112939875 "Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 12.9;Extravillous trophoblasts: 25.9;Hofbauer cells: 9.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044405, HPA050733" Uncertain Approved Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA044405: AB_10959783, HPA050733: AB_2681223" "unprognostic (5.26e-2)" "unprognostic (3.95e-2)" "unprognostic (2.86e-1)" "unprognostic (2.39e-1)" "unprognostic (2.48e-1)" "unprognostic (1.11e-1)" "unprognostic (7.61e-5)" "unprognostic (1.50e-3)" "unprognostic (1.61e-2)" "unprognostic (9.82e-3)" "unprognostic (1.68e-1)" "unprognostic (2.30e-1)" "unprognostic (1.04e-1)" "unprognostic (6.94e-2)" "unprognostic (1.13e-1)" "unprognostic (8.22e-2)" "unprognostic (9.10e-2)" 3.9 4.0 7.2 4.8 7.4 4.9 5.8 8.9 10.7 5.9 5.7 4.9 2.6 7.3 4.2 7.3 4.4 5.0 12.7 7.3 8.4 5.4 2.3 4.3 5.8 5.3 6.6 5.8 3.1 4.8 2.9 5.1 5.6 5.6 4.3 9.3 5.0 6.4 3.2 3.8 3.3 7.2 6.1 6.0 3.1 8.0 8.7 8.2 5.2 4.2 5.7 6.3 4.3 5.8 5.9 4.9 12.3 11.1 16.3 18.6 3.7 6.1 27.5 10.8 15.6 3.0 4.6 2.0 7.7 11.2 11.9 2.8 6.6 9.1 17.6 6.2 6.7 10.3 3.1 3.7 7.3 4.0 9.6 14.2 7.1 8.5 7.4 13.5 8.8 3.7 3.3 3.8 13.2 4.5 9.5 11.5 2.7 4.2 5.1 4.7 16.1 6.2 8.3 7.8 4.9 12.5 11.5 4.7 6.8 11.8 2.3 3.6 6.2 13.8 3.3 8.9 4.8 4.9 4.9 3.7 14.9 5.9 8.2 6.7 3.8 6.5 3.2 3.9 3.9 2.5 3.1 3.7 3.9 2.4 4.2 3.7 8.7 3.7 4.4 2.3 5.2 1.6 7.2 7.4 8.9 10.7 7.3 8.4 5.3 6.6 5.6 6.1 8.7 5.8 6.8 6.4 5.6 0.0 2.0 0.0 0.0 0.0 0.0 0.0 7.9 7.6 0.0 0.0 1.8 12.9 0.0 6.9 4.8 0.0 0.0 3.4 0.0 4.6 8.5 2.6 0.0 0.0 0.0 2.5 25.9 2.7 0.0 5.4 0.0 8.9 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 1.6 0.0 0.0 6.6 3.6 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 8.2 2.6 5.8 0.0 0.0 BNIP5 "C6orf222, DKFZp779B1540" ENSG00000189325 "BCL2 interacting protein 5" P0C671 6 36315761-36336888 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "intestine: 24.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "colorectal cancer: 8.7;pancreatic cancer: 5.1;stomach cancer: 8.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 1.0;OE19: 2.3;REH: 1.0;U-937: 1.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA038407, HPA058189" Uncertain Approved Cytosol NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" Cytosol "HPA038407: AB_10669644, HPA058189: AB_2683634" "unprognostic (1.97e-5)" "unprognostic (5.46e-3)" "unprognostic (3.93e-1)" "unprognostic (1.49e-1)" "unprognostic (7.52e-2)" "unprognostic (1.07e-1)" "unprognostic (1.81e-1)" "unprognostic (4.13e-1)" "unprognostic (1.22e-1)" "unprognostic (1.03e-1)" "unprognostic (6.75e-2)" "unprognostic (3.04e-2)" "unprognostic (4.55e-2)" "unprognostic (3.16e-2)" "unprognostic (3.98e-1)" "unprognostic (1.66e-4)" 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.7 24.7 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.1 0.0 0.1 0.0 5.7 0.0 0.0 0.0 0.0 0.2 23.5 0.1 0.0 0.0 4.2 1.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 1.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 BNIPL "BNIP-S, BNIP-Salpha, BNIP-Sbeta, BNIPl-1, BNIPL-2, PP753" ENSG00000163141 "BCL2 interacting protein like" Q7Z465 1 151036321-151047720 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 128.5;skin 1: 181.4;vagina: 69.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 17.2;Squamous epithelial cells: 42.7;Suprabasal keratinocytes: 57.1;Urothelial cells: 24.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "T-47d: 46.1" "Group enriched" "Detected in some" 9 "basal ganglia: 1.6;cerebellum: 2.4" "Not detected" "Not detected" HPA019946 Uncertain Cytosol NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA019946: AB_2732424" "unprognostic (2.62e-1)" "unprognostic (7.59e-3)" "unprognostic (3.63e-3)" "prognostic unfavorable (6.50e-4)" "unprognostic (6.58e-2)" "unprognostic (2.82e-2)" "unprognostic (3.32e-3)" "unprognostic (3.68e-2)" "unprognostic (3.12e-2)" "unprognostic (2.45e-1)" "unprognostic (3.88e-4)" "unprognostic (1.91e-1)" "unprognostic (8.43e-11)" "unprognostic (1.84e-2)" "unprognostic (6.49e-2)" "prognostic favorable (4.32e-4)" "unprognostic (6.81e-2)" 0.4 0.3 0.9 0.4 1.0 0.6 15.6 3.0 1.3 25.1 0.7 0.4 0.3 0.3 0.2 128.5 2.7 0.3 0.7 0.9 1.0 2.9 1.2 9.4 0.6 1.5 1.0 0.6 0.4 1.1 0.6 0.5 1.1 12.5 0.2 0.8 22.9 4.7 1.6 181.4 0.5 0.1 0.7 1.1 1.4 4.3 1.0 0.7 7.4 0.1 10.1 9.7 69.7 1.1 0.4 0.4 0.6 0.6 0.4 0.4 0.7 0.3 0.0 0.3 0.2 1.5 0.4 0.7 0.7 0.0 0.1 1.5 0.9 0.2 0.6 1.1 1.0 1.2 0.8 0.2 0.1 0.6 0.6 0.0 3.1 0.2 0.3 1.0 0.0 1.1 0.6 0.5 0.3 2.0 0.7 1.2 0.5 1.0 0.4 0.3 0.3 0.4 0.6 0.4 1.3 0.6 0.5 0.9 0.3 2.2 46.1 0.4 1.1 0.7 0.5 0.2 0.1 1.7 1.3 3.9 0.1 0.3 0.8 0.5 0.1 0.1 0.3 0.1 0.2 0.0 0.2 0.2 0.0 0.2 0.1 0.1 0.6 0.1 0.1 0.1 0.0 0.1 0.9 1.0 3.0 1.3 0.9 1.0 1.5 1.0 1.1 0.7 1.0 1.1 0.4 16.0 17.2 0.0 0.3 15.3 6.1 3.9 12.5 0.4 14.2 6.1 0.3 0.0 11.0 11.0 0.0 1.6 1.2 0.3 0.0 0.0 7.6 1.1 1.3 0.8 0.0 0.0 1.1 0.0 0.4 0.9 0.0 1.1 0.0 0.4 2.5 0.1 0.3 0.0 1.2 0.3 2.0 0.6 5.5 1.3 0.9 1.9 3.6 0.0 0.1 0.3 0.0 0.0 0.7 0.0 0.1 0.0 0.6 5.5 0.8 0.3 12.8 1.5 0.0 0.9 1.2 0.9 0.3 42.7 57.1 2.6 1.3 0.2 0.4 24.4 BTBD19 ENSG00000222009 "BTB domain containing 19" C9JJ37 1 44808482-44815585 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 9.0" "Cell type enhanced" "Detected in many" "Skeletal myocytes: 9.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 5.4;HUVEC TERT2: 5.1;TIME: 11.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042633, HPA076404" Uncertain Uncertain Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA042633: AB_2678091, HPA076404: AB_2686796" "unprognostic (4.69e-2)" "unprognostic (8.74e-3)" "unprognostic (1.82e-3)" "unprognostic (1.20e-4)" "unprognostic (5.32e-2)" "unprognostic (3.80e-2)" "unprognostic (1.11e-2)" "unprognostic (1.20e-1)" "unprognostic (3.70e-1)" "unprognostic (1.53e-2)" "unprognostic (2.76e-2)" "unprognostic (1.92e-1)" "prognostic unfavorable (4.18e-8)" "unprognostic (2.20e-3)" "unprognostic (2.78e-2)" "unprognostic (8.29e-2)" "unprognostic (1.70e-1)" 2.7 4.3 0.4 1.1 0.4 0.9 1.4 0.5 1.0 3.8 9.0 1.1 0.4 5.4 0.7 0.7 4.0 1.2 2.0 0.5 1.2 1.5 0.8 2.3 0.4 3.2 2.1 4.2 0.6 1.5 5.3 0.8 2.0 1.3 0.4 0.0 0.8 1.2 0.4 0.6 1.1 1.6 1.4 0.9 1.0 0.7 1.7 0.1 3.2 0.4 0.3 1.1 2.1 1.5 0.1 0.9 0.8 0.8 1.7 2.0 0.6 1.7 1.0 0.7 1.6 0.0 0.7 0.0 0.7 2.9 0.4 0.2 0.0 0.8 0.3 0.8 0.1 1.6 0.3 0.9 1.8 0.0 1.2 3.0 0.1 2.9 0.5 5.4 5.1 0.0 0.2 0.0 1.7 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.4 0.5 0.0 0.0 0.0 0.2 0.1 0.9 1.0 0.0 0.0 11.9 3.0 2.3 1.4 1.3 0.4 0.1 0.0 1.8 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.5 1.0 0.5 1.2 3.2 2.1 2.0 1.4 1.7 1.5 5.8 3.2 4.2 0.0 1.4 2.0 1.9 0.8 3.4 0.1 4.2 1.8 1.3 1.5 2.9 1.8 0.0 0.4 1.2 2.6 0.0 0.9 0.6 3.8 6.8 5.2 0.0 0.4 0.6 0.6 0.4 6.2 2.0 7.3 2.5 1.1 6.1 3.3 2.9 0.0 0.3 1.7 0.0 5.9 6.2 0.1 3.1 8.1 3.6 1.9 0.5 1.1 0.0 0.5 0.1 1.0 1.4 1.2 2.3 1.1 2.6 3.3 1.5 0.1 0.0 9.3 4.5 1.0 0.2 2.1 2.3 1.2 2.7 4.1 1.0 1.4 BTF3 "BTF3a, BTF3b, NACB" ENSG00000145741 "Basic transcription factor 3" P20290 5 73498408-73505635 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013007, HPA056420" Approved Supported Cytosol NA Yes 180000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Cytosol "CAB013007: , HPA056420: AB_2683125" "unprognostic (3.48e-3)" "unprognostic (2.11e-1)" "unprognostic (2.87e-3)" "unprognostic (1.86e-1)" "unprognostic (6.25e-2)" "unprognostic (1.41e-1)" "unprognostic (1.90e-3)" "unprognostic (1.78e-2)" "unprognostic (8.20e-3)" "unprognostic (5.18e-2)" "unprognostic (8.47e-2)" "unprognostic (1.01e-1)" "unprognostic (2.36e-2)" "unprognostic (1.06e-1)" "unprognostic (2.87e-1)" "unprognostic (1.26e-2)" "unprognostic (2.16e-1)" 633.3 440.1 241.0 373.7 251.2 861.1 763.0 250.7 307.9 658.2 234.9 593.6 460.9 547.0 422.0 735.8 584.3 376.6 477.8 230.9 261.7 469.8 522.5 416.4 644.4 256.5 247.8 1180.8 609.6 401.9 288.1 429.5 259.1 441.1 540.1 183.9 509.2 390.8 880.0 782.4 446.7 459.1 256.5 393.7 534.8 181.7 242.0 629.3 440.1 600.1 758.9 624.2 626.6 272.0 1148.3 747.2 798.7 1145.9 779.6 1301.4 1246.4 781.1 1084.9 1327.8 1267.4 972.1 1267.3 1719.2 1203.2 816.0 963.9 787.9 1176.6 2011.7 1517.2 716.2 1502.5 976.3 652.7 1280.2 1132.7 934.0 754.5 1139.7 1597.0 857.6 1572.3 1512.0 1227.4 975.3 924.1 1087.8 1134.7 1037.8 1410.0 1735.0 1017.4 423.0 742.0 1061.5 944.4 2147.0 1414.6 1126.0 930.6 1239.4 767.0 861.7 1650.4 744.4 1108.4 1884.6 894.7 569.6 780.5 690.2 2142.1 1020.7 1114.3 1607.2 757.0 1405.3 862.8 261.1 883.1 221.9 535.6 684.0 907.0 957.3 906.7 754.3 1140.2 788.4 986.3 892.7 116.0 878.6 556.1 637.6 1146.0 2128.9 241.0 251.2 250.7 307.9 230.9 261.7 256.5 247.8 259.1 256.5 242.0 272.0 753.2 246.8 324.7 17.0 889.7 1962.5 2039.6 2425.9 1664.7 138.9 1675.6 2355.4 357.8 566.2 908.0 323.7 43.8 1370.6 740.7 648.3 909.8 971.1 718.0 502.1 809.7 864.3 592.8 968.4 25.2 1219.7 2062.4 753.8 465.3 646.9 417.7 935.1 742.8 439.4 1066.3 85.8 29.3 1169.4 787.3 968.7 1357.2 464.2 1248.3 803.3 791.5 29.0 1487.9 376.5 726.1 20.6 49.6 1221.7 998.2 846.3 540.1 1626.5 1308.9 1229.5 432.9 137.6 644.2 1023.8 1051.0 333.7 238.2 1582.0 1953.2 1712.1 868.7 1029.7 1337.1 2269.9 BUB1B "Bub1A, BUBR1, MAD3L, SSK1" ENSG00000156970 "BUB1 mitotic checkpoint serine/threonine kinase B" O60566 15 40161023-40221123 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.8;lymphoid tissue: 35.7;testis: 22.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 23.5;Spermatocytes: 79.2;Spermatogonia: 26.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA008419 Supported Cytosol Yes Yes "Cluster 24: B-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA008419: AB_1078308" "unprognostic (4.40e-2)" "unprognostic (2.23e-1)" "unprognostic (4.65e-2)" "unprognostic (2.44e-3)" "unprognostic (9.66e-2)" "unprognostic (3.52e-2)" "prognostic unfavorable (7.43e-6)" "prognostic unfavorable (3.56e-4)" "unprognostic (3.69e-3)" "unprognostic (2.32e-1)" "prognostic unfavorable (1.79e-4)" "unprognostic (1.76e-2)" "unprognostic (0.00e+0)" "unprognostic (3.75e-2)" "unprognostic (4.66e-2)" "unprognostic (2.20e-1)" "unprognostic (3.94e-2)" 0.4 0.5 0.1 6.7 0.1 17.8 1.6 0.3 0.2 1.0 7.7 4.6 4.7 1.2 0.3 5.2 0.6 0.6 0.3 0.3 0.1 0.3 0.4 1.0 12.6 0.0 0.1 0.2 0.2 0.2 0.1 3.4 0.1 0.4 6.0 0.1 0.9 0.2 0.0 3.5 4.1 2.1 0.0 3.1 2.4 22.2 0.2 35.7 0.5 0.0 15.0 1.5 1.7 0.0 66.5 32.8 103.0 41.5 2.5 7.1 33.2 60.9 34.2 64.6 55.7 48.1 25.0 59.7 33.5 22.7 59.0 72.6 98.8 33.2 70.5 51.8 52.1 86.4 83.6 45.5 0.2 79.0 45.7 1.6 2.0 39.2 37.1 12.9 47.7 66.5 76.4 61.7 65.6 22.5 62.5 48.9 70.2 55.6 36.8 66.5 83.7 45.2 19.9 33.1 67.1 40.8 38.0 35.9 13.3 45.1 41.9 40.9 27.6 49.3 51.8 49.2 55.5 32.1 58.2 95.6 26.3 87.8 65.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.1 0.2 1.1 0.0 0.1 0.0 0.1 0.0 0.8 0.0 0.1 0.1 0.1 0.3 0.2 0.3 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.1 3.2 1.1 0.3 1.8 0.8 0.3 1.0 1.8 0.7 0.9 2.0 0.8 0.0 1.9 0.0 0.0 5.4 0.6 1.8 0.0 0.4 3.0 0.9 1.4 1.0 0.0 23.5 0.7 0.0 6.7 2.4 5.6 2.1 0.0 12.9 1.1 0.3 5.2 0.0 0.7 2.5 0.0 1.9 1.7 3.3 1.5 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 1.5 0.4 12.6 0.3 0.3 0.1 0.2 0.2 6.6 0.2 1.7 79.2 26.8 6.9 0.3 0.8 1.8 0.8 5.4 0.6 C11orf45 "FLJ43646, MGC35558" ENSG00000174370 "Chromosome 11 open reading frame 45" Q8TAV5 11 128899565-128906035 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 5.7;Hofbauer cells: 8.7;Kupffer cells: 5.9;Late spermatids: 8.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 11.2;U-937: 8.9" HPA039716 Approved Approved Cytosol "Secreted - unknown location" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" Cytosol "HPA039716: AB_10672892" "unprognostic (8.32e-2)" "unprognostic (3.93e-2)" "unprognostic (5.99e-3)" "unprognostic (1.35e-3)" "unprognostic (1.01e-1)" "unprognostic (9.93e-2)" "unprognostic (4.50e-5)" "unprognostic (1.97e-2)" "unprognostic (4.78e-2)" "unprognostic (3.10e-1)" "unprognostic (2.80e-1)" "unprognostic (9.27e-2)" "unprognostic (2.55e-9)" "unprognostic (2.37e-1)" "unprognostic (2.60e-2)" "unprognostic (6.87e-2)" "unprognostic (7.22e-2)" 0.6 3.3 1.7 0.7 4.4 0.8 0.9 0.6 2.1 1.0 0.8 0.7 1.4 0.5 0.6 2.9 1.0 2.0 4.5 1.4 1.6 2.0 0.5 2.6 0.8 1.9 1.9 0.9 2.6 3.8 2.3 2.1 1.6 1.1 0.9 0.2 1.6 2.8 0.1 6.6 0.9 0.5 1.1 1.5 1.8 1.1 2.3 2.4 1.8 0.2 0.9 1.2 1.3 2.2 2.4 4.5 0.0 0.0 0.3 0.4 1.6 0.8 4.7 1.7 4.2 6.3 5.8 0.0 3.2 0.5 4.2 2.3 2.4 11.2 0.8 0.0 1.1 0.3 2.7 0.0 0.2 0.0 0.0 0.3 1.5 1.3 0.9 3.8 1.0 3.5 0.0 0.2 2.0 1.2 2.6 2.4 1.8 1.0 3.9 1.1 4.6 0.5 3.9 1.1 0.0 0.2 1.8 5.0 0.3 1.2 0.8 4.4 0.5 0.0 6.2 0.0 0.8 0.1 0.0 0.0 0.8 8.9 0.2 0.0 0.6 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.9 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.2 1.7 4.4 0.6 2.1 1.4 1.6 1.9 1.9 1.6 1.1 2.3 2.2 0.1 0.0 0.5 0.0 0.0 2.8 1.3 0.9 5.7 0.0 0.3 0.4 1.7 0.0 0.2 0.0 0.0 2.0 0.0 0.1 1.9 1.0 2.0 0.3 0.1 0.2 0.0 0.0 0.3 0.8 2.1 0.3 0.0 0.5 1.3 0.3 0.4 0.0 8.7 0.0 0.2 0.1 0.0 5.9 0.8 8.2 0.0 2.2 0.0 2.8 0.6 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.4 1.5 1.7 3.0 0.9 1.2 0.2 0.1 0.2 1.1 C12orf71 LOC728858 ENSG00000214700 "Chromosome 12 open reading frame 71" A8MTZ7 12 27081057-27082578 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.4;testis: 3.2" "Cell type enriched" "Detected in some" 5 "Early spermatids: 19.9" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 10 "NK-cell: 1.0" "Lineage enriched" "Detected in single" 10 "NK-cells: 1.0" "Cell line enhanced" "Detected in single" "HDLM-2: 1.4" "Not detected" "Not detected" "HPA038359, HPA058728" Uncertain Approved Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 44: HDLM-2 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol "HPA038359: , HPA058728: AB_2683800" "unprognostic (1.14e-1)" "unprognostic (9.86e-2)" "unprognostic (1.61e-1)" "unprognostic (1.92e-1)" "unprognostic (2.36e-1)" "unprognostic (6.78e-3)" "unprognostic (9.90e-2)" "unprognostic (3.13e-1)" "unprognostic (7.12e-3)" "unprognostic (1.02e-1)" "unprognostic (6.73e-3)" "unprognostic (1.96e-1)" "unprognostic (4.15e-8)" "unprognostic (4.85e-2)" "unprognostic (9.71e-2)" "unprognostic (1.10e-1)" "unprognostic (1.01e-2)" 0.1 0.1 0.3 0.1 0.5 1.4 0.1 0.0 0.3 0.2 0.1 0.1 0.0 0.1 0.0 0.2 0.2 0.0 0.1 0.3 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.0 0.2 0.1 0.0 0.3 0.2 0.0 0.2 0.7 0.3 0.0 0.0 0.2 0.1 3.2 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.3 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.3 0.3 0.1 0.1 0.1 0.2 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.9 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 C14orf28 "DRIP-1, DRIP1" ENSG00000179476 "Chromosome 14 open reading frame 28" Q4W4Y0 14 44897275-44907257 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Early spermatids: 184.9;Late spermatids: 127.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059635 Approved Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 44: HDLM-2 - Immune response" "Cluster 34: Spermatids - Unknown function" Cytosol "HPA059635: AB_2684091" "unprognostic (5.41e-2)" "unprognostic (1.21e-2)" "unprognostic (3.23e-1)" "unprognostic (3.06e-6)" "unprognostic (1.18e-1)" "unprognostic (6.64e-3)" "unprognostic (2.37e-2)" "unprognostic (1.90e-2)" "unprognostic (2.25e-1)" "unprognostic (5.35e-2)" "unprognostic (3.13e-3)" "unprognostic (7.33e-2)" "unprognostic (3.26e-2)" "unprognostic (2.43e-1)" "unprognostic (2.30e-1)" "unprognostic (4.68e-2)" "unprognostic (2.01e-1)" 5.4 2.4 2.4 2.4 2.8 1.0 3.5 2.5 3.5 3.8 2.5 5.3 4.1 6.1 3.7 3.1 4.5 2.6 5.0 2.4 2.5 2.8 4.8 2.8 2.7 2.8 2.6 6.5 3.5 2.5 2.1 2.8 2.8 3.9 3.1 2.3 3.6 4.5 4.6 3.3 4.2 4.5 2.5 3.0 3.8 8.6 2.6 1.4 3.6 4.6 2.9 5.3 2.5 3.1 1.9 1.3 2.5 4.3 4.9 2.6 5.6 3.7 4.1 1.8 2.8 0.1 2.4 2.5 2.2 2.6 4.0 1.0 0.6 1.8 3.1 9.3 0.5 1.2 0.5 2.6 1.4 1.1 2.8 2.0 3.0 0.5 2.9 3.4 1.0 3.0 0.6 3.4 1.4 3.7 1.1 2.2 0.4 3.6 1.4 1.8 3.0 1.0 2.5 2.4 0.5 0.7 1.5 3.0 1.7 2.0 5.4 1.1 1.5 6.8 3.3 1.1 0.7 4.8 4.2 1.6 1.9 0.6 2.2 1.1 1.1 4.6 2.6 1.7 2.9 4.8 2.5 3.3 1.2 3.1 5.4 3.2 2.3 2.5 2.3 2.1 3.1 1.4 2.4 2.8 2.5 3.5 2.4 2.5 2.8 2.6 2.8 2.5 2.6 3.1 5.9 3.2 2.7 1.6 8.8 3.1 9.4 10.3 10.8 3.2 6.5 7.2 12.1 5.7 4.7 5.5 0.0 5.6 6.0 6.7 9.8 8.4 184.9 1.6 4.8 5.3 3.0 2.1 4.0 8.7 4.9 8.9 5.6 2.8 1.3 2.9 5.3 11.5 4.6 3.3 3.8 7.0 8.2 5.4 3.1 127.9 10.5 3.8 5.4 6.5 4.4 3.4 5.2 9.0 9.5 5.9 4.9 16.1 5.5 14.2 15.8 16.0 1.8 2.9 19.7 3.6 11.2 18.5 10.2 5.4 4.4 6.6 6.5 3.3 5.2 7.6 C15orf39 "DKFZP434H132, FLJ46337" ENSG00000167173 "Chromosome 15 open reading frame 39" Q6ZRI6 15 75195643-75212169 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 61.9;testis: 73.7" "Cell type enhanced" "Detected in many" "Early spermatids: 50.9;Late spermatids: 68.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "dendritic cells: 8.0;granulocytes: 23.5;monocytes: 16.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039961, HPA041907" Enhanced Enhanced Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" Cytosol "HPA039961: AB_10673024, HPA041907: AB_2677736" "unprognostic (3.53e-2)" "unprognostic (1.66e-1)" "unprognostic (4.57e-2)" "unprognostic (1.51e-2)" "unprognostic (1.47e-1)" "unprognostic (2.00e-1)" "unprognostic (2.20e-2)" "unprognostic (3.46e-2)" "prognostic favorable (7.94e-4)" "unprognostic (3.38e-2)" "unprognostic (2.74e-1)" "unprognostic (8.47e-2)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.07e-1)" "prognostic unfavorable (6.02e-4)" "unprognostic (2.95e-1)" "unprognostic (1.14e-1)" 14.9 15.5 4.4 12.7 4.6 61.9 13.7 2.4 8.3 13.7 4.6 10.8 11.5 14.4 1.9 20.4 16.1 7.9 14.4 3.3 5.7 8.6 4.3 15.3 10.9 6.3 5.4 18.2 14.5 15.7 8.9 15.2 4.6 8.8 5.3 1.8 14.4 6.8 4.1 15.3 10.2 7.2 5.0 25.5 9.6 73.7 7.7 8.7 11.1 3.8 6.7 15.0 14.4 4.2 20.5 41.2 8.8 10.3 11.7 7.6 26.4 5.8 11.7 6.7 7.2 51.2 27.8 45.9 19.1 8.6 24.0 27.0 37.6 17.5 1.9 45.0 42.7 91.0 19.6 35.4 13.3 26.4 90.1 10.0 13.7 14.2 6.6 8.3 17.2 17.1 39.7 66.4 2.2 12.3 25.5 32.2 27.4 13.6 16.3 23.0 6.6 49.3 4.1 15.9 25.4 8.1 13.4 30.6 21.2 8.8 10.5 33.2 14.7 11.6 17.3 20.6 17.0 47.8 32.9 26.3 11.4 50.3 11.5 8.5 6.4 18.6 1.7 11.7 1.3 1.1 1.0 1.2 3.9 0.7 0.7 1.1 23.5 3.4 16.2 8.0 1.4 4.1 4.4 4.6 2.4 8.3 3.3 5.7 6.3 5.4 4.6 5.0 7.7 4.2 13.0 25.6 5.5 0.7 7.8 14.9 7.0 5.5 19.9 0.3 8.1 5.8 2.3 7.2 9.6 3.7 0.0 12.6 17.7 13.5 0.0 15.8 50.9 17.2 10.0 10.4 7.7 5.9 0.4 14.6 16.8 7.8 8.6 30.0 17.7 14.3 10.8 2.8 12.4 0.0 1.0 6.1 6.1 23.6 10.5 68.8 11.8 24.0 7.2 1.9 31.6 0.7 12.3 1.0 0.1 18.1 26.1 10.9 19.9 5.2 3.4 1.6 8.1 2.2 13.1 6.5 10.0 37.2 5.6 15.5 14.2 20.9 7.3 3.7 8.6 17.8 C19orf12 "DKFZP762D096, MGC10922, MPAN, NBIA4, SPG43" ENSG00000131943 "Chromosome 19 open reading frame 12" Q9NSK7 19 29698886-29715789 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 118.9;tongue: 105.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 62.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046930 Approved Supported Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 44: HDLM-2 - Immune response" "Cluster 2: Hepatocytes - Metabolism" Cytosol "HPA046930: AB_10962836" "unprognostic (1.76e-1)" "unprognostic (2.22e-1)" "unprognostic (2.13e-1)" "unprognostic (1.01e-2)" "unprognostic (1.45e-1)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "unprognostic (9.01e-2)" "unprognostic (1.54e-1)" "unprognostic (9.94e-3)" "unprognostic (7.93e-3)" "unprognostic (5.27e-2)" "unprognostic (1.69e-2)" "unprognostic (1.74e-1)" "unprognostic (2.23e-1)" "unprognostic (3.22e-1)" "unprognostic (1.22e-3)" 118.9 25.3 22.1 14.4 25.8 4.4 40.8 16.6 24.8 13.8 12.6 16.8 19.5 14.3 9.0 13.2 12.8 12.9 30.9 23.9 22.7 20.8 69.3 11.3 21.2 20.5 20.3 14.7 17.1 15.4 14.5 13.2 21.7 14.1 9.3 8.5 18.1 12.4 62.2 14.7 17.6 13.4 16.8 16.0 12.9 7.3 23.1 14.1 10.7 105.5 13.6 15.2 11.7 19.9 19.9 39.4 18.4 23.2 45.0 27.5 28.8 23.1 22.7 22.5 29.2 19.1 8.1 16.1 24.1 29.1 20.4 8.5 15.7 9.5 15.1 42.8 28.3 18.0 13.5 33.2 25.1 14.0 22.8 31.8 20.2 13.7 10.9 18.0 20.1 9.8 14.0 20.3 23.7 13.8 9.9 10.1 11.1 17.3 9.9 19.2 19.1 12.3 17.2 20.1 11.3 23.8 13.9 17.8 37.0 18.8 7.6 15.4 20.9 47.4 37.0 19.5 21.2 28.4 27.1 12.0 28.3 8.4 20.3 1.1 2.3 1.4 16.0 2.5 9.4 4.6 9.1 11.6 2.2 3.6 9.2 11.5 2.8 7.1 2.7 5.0 11.9 8.0 22.1 25.8 16.6 24.8 23.9 22.7 20.5 20.3 21.7 16.8 23.1 19.9 9.6 12.8 13.7 9.4 13.7 12.7 11.1 8.2 14.8 15.8 13.2 9.4 30.1 2.8 7.3 9.2 6.2 29.2 21.7 9.2 15.6 17.1 1.8 8.5 16.0 10.4 3.6 9.5 19.5 23.1 25.5 20.0 8.2 8.8 16.5 16.2 14.6 62.4 15.6 5.0 18.3 7.5 8.2 12.5 9.9 1.8 28.9 8.7 10.6 8.4 20.1 15.8 41.2 12.1 17.4 20.0 11.0 29.3 20.7 12.8 24.0 37.5 6.6 9.6 6.6 24.6 13.3 4.6 5.3 10.1 7.7 21.9 21.6 23.8 8.2 7.8 C1orf158 MGC35194 ENSG00000157330 "Chromosome 1 open reading frame 158" Q8N1D5 1 12746200-12763699 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 18.1;fallopian tube: 26.7;testis: 48.9" "Cell type enhanced" "Detected in some" "Early spermatids: 223.3;Endometrial ciliated cells: 50.3;Late spermatids: 92.8;Respiratory ciliated cells: 88.1;Spermatocytes: 70.7" "Group enriched" "Detected in some" 6 "endometrial cancer: 1.6;glioma: 1.0;ovarian cancer: 0.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA028396 Uncertain Cytosol NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA028396: AB_10603451" "unprognostic (1.11e-2)" "unprognostic (4.94e-3)" "unprognostic (4.62e-1)" "unprognostic (8.00e-2)" "unprognostic (4.18e-1)" "unprognostic (1.03e-2)" "unprognostic (2.45e-1)" "unprognostic (3.51e-1)" "unprognostic (1.35e-1)" "unprognostic (2.68e-2)" 0.0 0.0 0.9 0.0 1.1 0.3 0.0 1.0 0.4 1.1 18.1 0.0 0.0 0.4 0.1 0.1 26.7 0.0 0.0 0.9 1.0 0.0 0.0 1.9 0.1 4.3 5.9 0.1 0.1 0.0 0.6 0.1 3.4 0.0 0.0 0.1 0.1 0.0 1.2 0.4 0.0 0.0 3.3 0.1 0.1 48.9 1.9 0.0 0.6 0.0 0.0 0.0 0.0 3.6 0.0 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.9 1.1 1.0 0.4 0.9 1.0 4.3 5.9 3.4 3.3 1.9 3.6 0.0 3.2 0.5 0.3 0.0 0.0 0.1 3.0 0.0 0.0 0.0 0.0 0.3 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 223.3 50.3 0.4 0.2 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.7 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.1 0.0 0.0 92.8 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.1 0.0 0.1 88.1 0.0 6.6 0.1 1.3 70.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 C1orf198 "DKFZp667D152, FLJ14525, FLJ16283, FLJ38847, MGC10710" ENSG00000119280 "Chromosome 1 open reading frame 198" Q9H425 1 230837119-230869589 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 131.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 192.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 13.1" "Lineage enriched" "Detected in all" 4 "granulocytes: 13.1" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 138.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004798 Approved Supported Cytosol "Intracellular and membrane" NA NA 80000 "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA004798: AB_1848722" "unprognostic (7.44e-2)" "unprognostic (1.89e-1)" "unprognostic (1.17e-2)" "unprognostic (6.61e-2)" "unprognostic (2.33e-1)" "unprognostic (2.64e-2)" "unprognostic (2.46e-1)" "unprognostic (1.52e-1)" "unprognostic (1.65e-1)" "unprognostic (2.32e-1)" "unprognostic (3.75e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (4.50e-5)" "unprognostic (3.53e-2)" "unprognostic (4.95e-2)" "unprognostic (1.38e-1)" "unprognostic (3.77e-2)" 39.7 13.4 77.5 11.0 106.4 5.3 30.0 93.3 83.7 36.5 41.1 35.2 11.8 38.8 14.9 14.9 32.7 32.3 45.4 72.6 85.0 17.3 14.7 66.9 15.5 108.4 105.1 27.3 27.9 20.1 7.6 31.1 108.9 21.4 11.4 9.8 23.4 32.3 106.2 34.0 13.9 46.1 97.8 18.0 29.9 6.8 94.5 6.6 34.9 26.1 9.1 33.2 26.4 131.3 22.4 16.7 44.9 30.8 81.9 59.9 76.7 40.4 63.7 20.4 20.6 53.0 12.3 26.8 24.5 138.1 10.3 14.1 23.5 8.9 15.0 87.5 22.3 4.2 15.0 17.9 35.7 13.9 4.0 72.9 13.4 8.1 8.9 43.7 12.9 16.9 8.7 9.0 14.1 15.0 11.0 6.6 52.6 49.5 13.7 25.6 32.1 6.0 16.2 26.7 26.0 41.5 20.5 27.2 14.2 23.6 34.6 11.8 10.3 32.9 32.8 7.7 24.5 16.0 7.7 8.0 8.7 8.7 95.3 13.1 1.3 0.3 2.0 2.7 2.4 1.9 1.3 0.8 1.7 1.2 2.6 2.3 1.0 2.9 1.3 0.2 0.6 4.7 77.5 106.4 93.3 83.7 72.6 85.0 108.4 105.1 108.9 97.8 94.5 131.3 11.1 192.3 23.2 35.3 1.2 26.0 13.1 6.4 7.4 2.0 32.7 23.7 36.4 32.9 17.3 11.0 10.4 17.5 1.3 2.6 1.9 41.9 11.4 8.2 8.9 11.6 5.4 9.9 2.6 26.3 32.2 33.2 3.6 10.6 2.5 15.1 8.6 4.5 11.0 25.2 5.3 9.0 8.2 1.8 19.4 8.3 13.4 11.6 65.8 13.1 3.6 12.8 0.0 6.0 67.5 31.1 3.7 9.1 2.5 21.3 2.8 7.4 12.2 4.6 32.9 26.8 45.1 10.4 5.7 8.9 29.0 12.9 3.4 5.2 6.9 18.7 C3orf18 G20 ENSG00000088543 "Chromosome 3 open reading frame 18" Q9UK00 3 50558025-50571027 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 29.3;Early spermatids: 54.2;Late spermatids: 62.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 2.2;NK-cells: 2.0;T-cells: 6.3" "Cell line enhanced" "Detected in many" "HDLM-2: 48.8" "Group enriched" "Detected in all" 4 "cerebellum: 28.2;olfactory bulb: 27.5" "Low region specificity" "Detected in all" HPA012105 Approved Approved Cytosol No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 34: Spermatids - Unknown function" Cytosol "HPA012105: AB_1845717" "unprognostic (9.29e-3)" "unprognostic (1.46e-2)" "unprognostic (6.96e-2)" "unprognostic (5.00e-2)" "unprognostic (8.19e-2)" "unprognostic (4.05e-1)" "unprognostic (1.44e-1)" "unprognostic (1.05e-2)" "unprognostic (1.64e-1)" "unprognostic (1.76e-1)" "unprognostic (2.10e-3)" "unprognostic (1.29e-2)" "prognostic favorable (2.80e-9)" "unprognostic (7.65e-2)" "unprognostic (4.49e-1)" "unprognostic (2.18e-1)" "unprognostic (1.59e-1)" 6.1 8.7 23.0 2.9 23.6 0.9 5.6 30.0 24.0 10.8 25.8 11.9 1.8 10.6 4.4 3.5 9.3 3.6 33.3 22.2 25.6 9.4 4.9 3.7 3.8 23.6 24.9 12.6 6.6 27.3 12.5 2.1 23.2 9.2 2.6 28.4 7.1 9.8 36.2 3.1 5.3 9.5 22.8 5.2 10.1 19.7 25.1 3.1 9.0 26.8 3.6 9.5 6.4 22.1 1.8 2.7 3.1 0.6 10.1 9.0 1.0 11.1 17.2 9.9 7.2 0.2 2.8 2.3 2.6 15.2 9.3 0.2 0.0 4.3 5.2 48.8 0.3 5.0 6.9 0.8 5.0 0.0 6.0 8.9 0.6 9.6 0.5 7.9 1.9 7.2 1.1 2.2 5.9 0.4 0.4 1.5 3.8 1.9 12.3 1.0 0.3 2.7 0.6 0.4 3.4 16.1 2.9 0.6 0.3 3.5 3.4 1.3 0.6 9.9 7.7 18.1 1.4 2.8 2.5 0.3 14.0 5.1 0.2 0.0 0.4 0.7 5.1 0.1 6.3 2.2 4.3 4.8 0.4 1.4 5.0 6.1 0.0 2.0 0.1 0.8 2.2 2.5 23.0 23.6 30.0 24.0 22.2 25.6 23.6 24.9 23.2 22.8 25.1 22.1 1.8 0.0 1.1 8.1 2.2 1.1 1.1 0.9 1.2 10.2 1.8 2.0 29.3 0.0 1.4 1.8 8.4 0.4 1.3 0.3 3.9 2.1 54.2 1.1 2.3 2.6 1.8 0.0 5.6 1.8 0.8 4.9 1.5 0.5 0.0 3.1 2.5 2.2 1.6 1.7 8.3 0.7 0.0 1.3 0.3 62.6 4.7 1.1 0.0 3.7 8.9 12.4 3.1 3.0 3.3 0.7 0.1 4.1 1.6 0.5 0.1 3.5 1.2 17.3 13.1 5.6 5.3 2.7 2.5 0.1 0.4 0.1 3.0 2.7 0.3 0.2 C3orf70 ENSG00000187068 "Chromosome 3 open reading frame 70" A6NLC5 3 185076838-185153060 "Cancer-related genes, Predicted intracellular proteins" Neurogenesis "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.9;smooth muscle: 14.8" "Cell type enhanced" "Detected in many" "Astrocytes: 45.7;Bipolar cells: 76.8;Melanocytes: 39.2;Oligodendrocyte precursor cells: 143.2;Peritubular cells: 49.7" "Cancer enhanced" "Detected in many" "glioma: 10.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RH-30: 3.9;SCLC-21H: 16.4;SK-BR-3: 7.2;WM-115: 8.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041861 Uncertain Approved Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "HPA041861: AB_10804119" "unprognostic (1.45e-1)" "unprognostic (2.17e-3)" "unprognostic (3.92e-3)" "unprognostic (2.77e-1)" "unprognostic (2.31e-1)" "unprognostic (6.62e-4)" "unprognostic (5.56e-2)" "unprognostic (1.05e-1)" "unprognostic (1.11e-1)" "unprognostic (1.32e-1)" "unprognostic (5.98e-3)" "unprognostic (9.91e-2)" "prognostic unfavorable (6.40e-6)" "unprognostic (1.06e-1)" "unprognostic (8.48e-2)" "unprognostic (6.57e-2)" "unprognostic (7.84e-2)" 2.2 0.8 10.8 2.4 8.5 0.1 1.3 7.2 8.8 3.1 0.0 11.1 2.6 9.8 2.6 5.1 5.2 2.2 2.0 9.9 9.1 0.5 0.3 0.9 0.4 15.9 11.5 2.3 0.2 2.1 0.8 1.3 10.1 5.1 4.1 3.9 3.0 8.4 0.5 1.5 3.6 14.8 13.6 2.1 2.8 4.0 12.0 0.3 1.1 0.6 0.6 4.9 2.0 14.0 0.0 0.1 1.9 0.0 0.0 0.0 0.1 2.6 0.1 0.4 0.0 1.2 0.0 0.0 0.0 0.3 0.1 0.0 0.9 0.0 0.1 0.0 0.6 2.2 0.1 0.5 0.0 0.3 3.6 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.8 2.0 0.1 0.0 3.9 0.0 0.0 0.4 16.4 0.1 0.8 7.2 0.4 0.0 0.4 1.8 0.6 0.0 1.9 0.0 1.2 0.0 0.0 0.0 0.0 0.0 8.9 0.6 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.1 0.1 0.0 0.0 10.8 8.5 7.2 8.8 9.9 9.1 15.9 11.5 10.1 13.6 12.0 14.0 5.1 0.0 0.0 45.7 1.0 4.1 0.3 0.0 0.6 76.8 1.0 0.5 1.6 0.0 0.0 0.0 0.0 10.8 0.0 9.1 0.0 0.1 1.2 0.1 2.3 4.4 1.2 0.0 13.8 0.2 0.6 3.8 0.0 0.1 0.0 3.9 6.8 0.0 4.0 3.3 19.4 8.8 0.0 0.6 0.7 1.5 3.4 0.3 39.2 6.5 0.6 2.5 0.0 143.2 10.1 0.5 2.2 49.7 0.1 0.3 4.6 0.1 0.0 7.3 6.6 1.3 15.4 6.8 12.5 0.2 1.8 0.8 0.2 1.8 6.3 0.3 C4orf48 ENSG00000243449 "Chromosome 4 open reading frame 48" Q5BLP8 4 2041993-2043970 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 97.9;choroid plexus: 62.6;pituitary gland: 74.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 412.4;Paneth cells: 484.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 158.3;NB-4: 117.3;PC-3: 343.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052447 Uncertain Approved Cytosol "Secreted to blood" NA NA 190000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA052447: AB_2681837" "unprognostic (7.96e-2)" "unprognostic (2.57e-3)" "unprognostic (2.08e-1)" "unprognostic (3.20e-2)" "unprognostic (4.01e-2)" "unprognostic (8.26e-2)" "unprognostic (4.85e-3)" "unprognostic (2.51e-3)" "unprognostic (2.28e-3)" "unprognostic (1.80e-1)" "unprognostic (1.95e-2)" "unprognostic (5.55e-2)" "unprognostic (3.42e-2)" "unprognostic (5.38e-3)" "unprognostic (2.68e-1)" "unprognostic (5.55e-2)" "unprognostic (3.17e-3)" 13.5 18.3 50.0 4.6 68.4 2.7 9.6 71.0 66.6 5.2 62.6 20.4 2.7 5.5 0.2 4.3 7.8 0.4 8.2 49.4 60.8 20.2 4.0 7.9 1.3 81.5 63.2 6.6 18.9 2.4 74.5 2.1 58.6 7.1 0.9 0.2 9.2 1.4 1.2 3.1 16.3 0.6 67.8 18.5 11.9 56.1 60.3 0.3 9.3 0.0 0.6 6.8 2.9 97.9 33.4 27.1 5.3 24.9 2.4 3.9 35.3 31.2 6.0 5.6 5.3 18.6 19.6 4.4 29.2 1.2 10.4 9.2 0.6 3.5 1.7 20.1 158.3 10.5 15.8 10.7 5.2 21.7 70.3 3.0 5.9 1.2 0.0 1.8 5.9 17.9 35.1 0.1 3.9 20.6 24.6 117.3 15.8 1.8 343.1 56.1 8.3 11.2 5.0 12.3 42.7 60.0 15.3 0.7 47.7 0.5 8.3 10.3 26.5 14.7 31.9 11.0 35.3 23.8 22.4 0.4 14.6 13.2 20.8 88.5 451.6 431.5 123.6 325.6 127.5 187.7 157.2 138.3 270.0 167.9 89.1 92.9 349.2 29.6 290.7 301.1 199.8 192.8 50.0 68.4 71.0 66.6 49.4 60.8 81.5 63.2 58.6 67.8 60.3 97.9 13.3 0.0 1.9 8.8 58.1 21.9 6.6 13.2 7.4 12.0 147.0 139.8 10.6 20.0 14.2 200.5 0.0 8.0 52.8 412.4 70.5 320.8 97.1 326.7 92.6 42.1 235.1 30.7 5.6 222.7 116.5 47.7 35.7 107.3 107.5 209.0 123.1 11.9 235.5 18.5 8.2 154.2 44.7 272.1 113.3 350.5 19.3 158.9 327.3 7.5 205.2 78.8 20.6 6.0 41.1 198.2 484.2 28.2 84.1 10.9 223.7 7.9 28.8 15.0 13.1 1.7 53.2 99.7 193.2 5.7 10.1 13.1 73.9 50.9 117.1 11.1 C6orf47 "D6S53E, G4" ENSG00000204439 "Chromosome 6 open reading frame 47" O95873 6 31658298-31660778 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "A549: 4.5;HBEC3-KT: 7.6;HDLM-2: 4.7;HEK 293: 6.1;U-2 OS: 5.5;U-266/84: 5.5" "Low region specificity" "Detected in all" HPA045281 Uncertain Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "HPA045281: AB_10961000" "unprognostic (5.99e-2)" "unprognostic (5.71e-2)" "unprognostic (1.27e-1)" "unprognostic (1.04e-1)" "unprognostic (9.92e-2)" "unprognostic (6.74e-2)" "unprognostic (2.09e-1)" "unprognostic (3.24e-2)" "unprognostic (3.27e-1)" "unprognostic (5.04e-2)" "unprognostic (2.93e-2)" "unprognostic (1.15e-1)" "unprognostic (1.66e-3)" "unprognostic (6.78e-3)" "unprognostic (2.38e-1)" "unprognostic (7.73e-2)" "unprognostic (3.59e-3)" 11.2 12.9 0.4 0.4 0.5 0.2 10.8 1.1 0.7 11.9 0.2 18.0 0.0 15.1 3.2 21.4 12.1 1.0 17.2 0.4 0.5 15.0 10.9 12.0 1.4 0.7 0.5 11.2 13.1 0.6 11.6 0.8 0.7 12.4 1.0 0.6 13.5 0.0 18.9 17.9 17.6 0.0 0.5 18.1 15.5 4.8 0.6 0.7 11.5 0.0 0.0 16.6 13.1 0.8 0.1 4.5 0.0 0.3 3.2 0.1 0.5 0.0 0.0 0.1 0.0 0.3 0.6 3.0 2.4 3.8 0.0 0.0 0.0 7.6 0.0 4.7 6.1 0.0 0.0 0.4 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.3 0.0 0.3 0.0 1.2 3.8 0.9 2.6 0.3 0.0 0.1 0.0 0.0 0.0 1.1 0.4 5.5 0.0 0.2 3.7 5.5 0.9 1.9 0.0 0.2 0.6 1.5 2.8 2.6 1.0 1.3 1.9 0.7 1.6 1.0 1.4 2.0 0.8 1.8 0.7 0.9 0.6 1.4 1.9 0.4 0.5 1.1 0.7 0.4 0.5 0.7 0.5 0.7 0.5 0.6 0.8 8.7 6.4 10.9 0.0 16.6 25.1 29.1 14.6 18.2 16.0 12.2 6.5 1.5 25.8 11.5 12.9 8.4 20.0 17.7 42.2 25.4 24.2 0.0 4.3 7.8 10.9 6.7 6.1 0.0 28.9 15.1 11.2 11.7 6.1 11.4 12.8 15.4 8.5 18.2 6.7 0.0 21.6 4.1 17.4 18.7 0.0 16.1 17.1 8.8 0.0 19.4 12.5 32.0 0.0 0.0 29.9 29.0 21.8 5.1 25.6 40.9 18.1 5.0 13.5 32.9 13.0 14.2 1.0 5.5 20.9 26.9 23.8 16.1 15.8 26.2 47.0 C6orf62 "DKFZP564G182, FLJ12619, XTP12" ENSG00000112308 "Chromosome 6 open reading frame 62" Q9GZU0 6 24704861-24719998 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Kupffer cells: 354.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030564, HPA030566" Supported Approved Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA030564: AB_10600000, HPA030566: AB_10599425" "unprognostic (2.07e-2)" "unprognostic (2.92e-1)" "unprognostic (7.10e-2)" "unprognostic (6.70e-2)" "unprognostic (1.14e-1)" "unprognostic (1.02e-2)" "prognostic unfavorable (5.77e-5)" "unprognostic (1.18e-1)" "unprognostic (3.67e-1)" "prognostic favorable (4.04e-4)" "unprognostic (4.16e-3)" "unprognostic (3.94e-2)" "unprognostic (3.08e-2)" "unprognostic (9.01e-2)" "unprognostic (4.03e-1)" "unprognostic (1.93e-2)" "prognostic favorable (3.62e-6)" 110.0 82.6 105.0 115.1 108.3 118.0 87.3 101.8 112.5 60.7 92.1 76.5 90.3 70.6 100.7 56.6 76.6 62.7 59.7 94.2 103.9 92.9 107.5 96.5 144.3 121.4 120.6 93.8 121.8 71.2 45.4 87.4 106.2 84.2 76.8 151.0 94.0 75.4 84.1 93.5 93.1 69.2 107.8 156.2 110.3 125.0 126.8 133.1 85.5 58.3 143.0 73.7 36.9 109.6 154.6 73.9 108.2 169.8 106.6 142.2 118.5 178.0 172.6 204.4 211.2 91.8 116.7 177.9 258.3 172.0 230.8 114.5 103.7 137.1 221.0 301.2 61.9 194.0 104.8 112.7 191.0 235.0 201.4 106.0 267.6 138.6 182.8 152.2 162.0 97.8 160.6 121.6 199.3 96.3 160.4 325.9 118.0 79.9 86.0 127.8 126.0 164.7 131.2 165.5 170.9 99.5 219.8 239.4 349.4 105.4 197.1 174.2 192.7 214.7 108.8 83.7 239.4 289.6 494.0 213.6 75.9 294.8 209.8 214.5 246.5 271.9 211.0 253.7 227.1 204.4 215.0 229.7 192.9 170.8 216.6 241.0 177.8 223.4 277.4 198.1 226.3 522.4 105.0 108.3 101.8 112.5 94.2 103.9 121.4 120.6 106.2 107.8 126.8 109.6 136.4 83.3 76.7 67.3 91.1 57.5 53.0 56.7 58.6 56.6 107.7 86.7 36.6 94.4 56.3 93.8 50.1 50.8 147.9 105.8 37.2 63.4 147.2 83.1 92.0 85.9 95.9 128.6 50.9 74.0 62.2 78.0 86.6 112.8 55.2 122.8 86.7 132.8 90.1 42.1 39.4 89.3 48.8 354.8 105.3 53.9 54.0 138.8 49.8 94.6 120.8 43.6 96.8 35.2 53.1 83.2 84.9 47.4 54.3 98.3 90.2 71.5 80.5 63.3 52.6 120.5 64.9 98.9 101.6 103.2 56.0 75.2 95.7 61.6 98.8 63.3 C9orf43 MGC17358 ENSG00000157653 "Chromosome 9 open reading frame 43" Q8TAL5 9 113410054-113429690 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "testis: 45.6" "Group enriched" "Detected in some" 8 "Early spermatids: 114.2;Late spermatids: 226.0;Spermatocytes: 91.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" HPA021310 Approved Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA021310: AB_1845825" "unprognostic (2.91e-2)" "unprognostic (9.63e-2)" "unprognostic (2.19e-1)" "unprognostic (1.18e-1)" "unprognostic (2.63e-1)" "unprognostic (6.58e-3)" "unprognostic (2.06e-1)" "unprognostic (1.77e-2)" "unprognostic (1.23e-1)" "unprognostic (8.90e-2)" "unprognostic (1.97e-2)" "unprognostic (5.96e-3)" "unprognostic (1.51e-1)" "unprognostic (7.32e-2)" "unprognostic (1.33e-1)" "unprognostic (3.21e-2)" "unprognostic (1.63e-1)" 0.3 1.5 0.9 0.1 1.0 1.9 0.5 0.9 1.2 0.2 0.8 0.2 0.1 0.2 1.2 0.3 0.7 0.3 0.2 0.9 1.2 1.2 1.5 0.2 0.4 1.3 1.6 0.8 0.8 0.9 1.4 0.2 1.2 0.5 0.2 1.2 0.7 0.4 0.1 0.5 0.2 0.0 1.3 0.4 0.5 45.6 1.1 0.4 0.8 0.3 0.4 0.2 0.2 1.3 0.5 0.4 0.2 0.7 0.6 0.3 0.3 0.2 0.4 0.7 0.5 0.5 0.4 1.3 0.4 0.1 1.4 0.9 0.2 0.6 0.2 1.1 0.2 1.1 0.8 0.2 0.5 0.2 0.1 0.7 1.0 0.8 1.0 0.4 0.6 1.5 0.7 1.2 0.3 1.0 0.5 0.3 0.3 0.6 1.6 0.3 0.2 0.7 0.7 0.2 1.2 0.3 1.2 0.5 0.7 0.5 1.6 0.1 0.0 1.0 0.2 0.6 1.0 0.7 1.5 2.0 0.5 0.4 0.3 0.0 0.1 0.0 0.3 0.3 0.0 0.3 0.1 0.4 0.2 0.1 0.3 0.4 0.4 0.2 0.0 0.3 0.0 0.1 0.9 1.0 0.9 1.2 0.9 1.2 1.3 1.6 1.2 1.3 1.1 1.3 0.4 0.0 0.0 4.9 1.5 0.6 0.6 0.5 1.2 1.7 0.8 0.9 0.1 0.0 1.6 0.0 0.0 0.5 0.3 0.2 1.9 0.3 114.2 3.0 0.7 0.7 0.0 0.8 0.6 0.2 0.4 0.2 0.0 0.6 0.0 0.7 0.0 0.9 0.3 0.0 0.7 0.1 0.0 0.3 0.4 226.0 2.1 0.5 0.0 0.0 0.7 1.8 0.0 0.5 1.8 0.9 0.0 1.5 1.8 0.3 0.1 0.9 6.7 2.8 0.0 0.7 0.3 91.5 17.9 0.7 0.0 0.0 0.4 0.7 0.2 0.6 CAD GATD4 ENSG00000084774 "Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase" P27708 2 27217369-27243943 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Allosteric enzyme, Hydrolase, Ligase, Multifunctional enzyme, Transferase" "Cancer-related genes, Congenital disorder of glycosylation, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007781, HPA065158, HPA069341" Supported Supported Cytosol NA No 260000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Cytosol "CAB007781: AB_562057, HPA065158: , HPA069341: AB_2686125" "unprognostic (1.69e-1)" "unprognostic (7.34e-2)" "unprognostic (1.49e-1)" "unprognostic (4.71e-3)" "unprognostic (2.55e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (1.72e-11)" "unprognostic (1.25e-1)" "unprognostic (2.22e-1)" "unprognostic (2.37e-1)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "prognostic unfavorable (1.82e-4)" "unprognostic (6.94e-2)" "unprognostic (1.75e-1)" "unprognostic (1.14e-1)" "unprognostic (5.93e-3)" 15.0 13.5 12.7 12.4 14.1 9.0 14.9 12.7 15.5 19.8 12.2 16.5 8.5 23.8 9.9 19.2 19.3 7.7 11.6 12.3 12.8 18.0 27.8 12.3 14.9 13.8 13.5 22.3 22.3 5.9 18.7 7.5 14.5 15.2 7.8 5.0 12.3 8.8 10.3 18.7 16.1 11.9 12.7 20.1 14.0 22.2 14.2 11.6 15.8 5.9 10.5 16.9 15.8 15.2 75.2 66.4 28.9 58.4 46.1 37.6 22.9 31.0 21.4 38.3 27.0 75.7 29.2 66.4 27.4 28.5 29.6 41.4 85.7 41.1 28.5 43.8 69.2 95.2 55.0 40.0 23.0 75.7 46.2 28.8 33.1 55.7 63.0 17.8 41.6 60.6 68.3 36.0 34.2 74.8 48.7 112.0 69.7 31.3 49.7 84.0 86.5 69.5 28.6 37.6 57.9 29.1 43.3 30.5 37.4 21.3 23.9 31.3 37.7 57.7 47.5 45.5 63.5 74.0 51.8 135.2 23.3 71.7 51.0 0.0 0.8 0.4 3.1 1.5 2.5 3.4 4.4 5.2 1.9 3.1 2.8 2.8 0.5 2.7 0.9 3.4 5.9 2.0 12.7 14.1 12.7 15.5 12.3 12.8 13.8 13.5 14.5 12.7 14.2 15.2 4.2 3.2 3.9 12.7 5.3 3.7 4.3 5.0 5.7 10.6 7.1 8.6 8.3 10.0 4.7 1.8 16.7 5.9 3.9 3.9 0.0 6.1 1.5 2.9 7.9 5.1 6.6 9.7 5.6 3.7 6.6 7.0 6.1 4.3 4.5 16.9 3.3 6.6 7.7 6.7 5.7 5.8 0.0 3.0 1.9 1.9 6.2 3.6 3.6 6.5 4.7 4.1 5.2 8.5 7.4 5.9 1.9 9.8 7.3 8.0 2.5 2.0 3.5 6.8 0.0 8.2 5.2 5.6 12.1 6.2 3.4 2.2 5.1 9.7 7.5 2.2 CALB2 CAL2 ENSG00000172137 "Calbindin 2" P22676 16 71358713-71390436 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 100.5;brain: 131.9;breast: 53.5" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 97.8;granulocytes: 251.5;Granulosa cells: 44.1;Theca cells: 70.2" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 4 "hypothalamus: 76.3;medulla oblongata: 89.5;midbrain: 42.2;pons: 86.7;thalamus: 131.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 21.5;HEL: 63.9;HMC-1: 133.0;U-2 OS: 38.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "thalamus: 449.0" "CAB000106, HPA007305, HPA007306" Enhanced Supported Enhanced Cytosol NA NA 9600 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" Cytosol "CAB000106: AB_2068519, HPA007305: AB_1078386, HPA007306: AB_1078385" "unprognostic (1.10e-1)" "unprognostic (1.90e-2)" "prognostic unfavorable (5.78e-5)" "unprognostic (1.75e-3)" "unprognostic (5.80e-2)" "unprognostic (1.43e-1)" "unprognostic (1.59e-1)" "unprognostic (4.55e-3)" "unprognostic (4.28e-1)" "unprognostic (1.32e-1)" "unprognostic (3.06e-3)" "unprognostic (1.35e-2)" "unprognostic (5.54e-4)" "unprognostic (1.97e-3)" "unprognostic (6.30e-2)" "unprognostic (4.72e-2)" "unprognostic (1.04e-2)" 100.5 36.6 19.9 4.1 15.4 0.0 53.5 16.5 20.0 3.5 4.1 13.8 0.7 0.7 0.5 7.7 7.7 1.1 7.7 12.8 76.3 0.3 0.2 3.6 0.1 89.5 42.2 11.4 0.7 0.0 14.3 0.0 86.7 0.9 4.7 23.6 11.1 0.4 0.5 4.9 6.2 1.7 16.0 0.1 1.0 13.0 131.9 0.1 0.2 0.2 0.9 2.0 2.7 8.4 19.1 2.0 17.0 0.0 0.6 0.1 3.3 0.6 0.3 0.5 0.1 0.1 21.5 0.0 0.3 0.2 2.7 3.7 0.0 0.0 0.2 0.1 0.1 63.9 0.0 0.6 0.1 0.0 133.0 0.0 0.0 1.3 0.2 0.3 0.0 1.6 0.0 0.5 0.1 0.3 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.2 0.1 0.1 0.2 0.1 0.6 0.0 0.1 0.0 3.1 38.0 0.3 3.8 0.0 0.1 0.0 3.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.9 15.4 16.5 20.0 12.8 76.3 89.5 42.2 86.7 16.0 131.9 8.4 0.5 9.6 7.2 0.3 0.0 0.3 0.1 0.2 0.0 12.5 10.3 2.3 0.4 1.5 0.0 0.0 6.2 0.0 0.0 0.0 0.0 1.8 2.6 0.3 10.8 0.7 0.0 0.0 0.4 97.8 0.1 29.6 0.0 0.1 251.5 44.1 0.0 0.1 0.1 30.3 17.4 0.0 0.0 0.0 0.4 2.4 6.2 1.2 5.4 1.0 0.0 2.5 0.0 0.0 0.6 16.5 0.0 0.0 0.1 0.1 0.0 0.0 1.5 10.3 0.0 0.2 1.9 1.8 5.0 0.0 0.0 0.1 3.5 70.2 0.0 0.2 CALM1 "CALML2, CAMI, DD132, PHKD" ENSG00000198668 "Calmodulin 1" P0DP23 14 90396502-90408268 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction" "Disease variant, FDA approved drug targets, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018558, HPA044999" Supported Supported Cytosol NA NA 75000000 "Cluster 44: Non-specific - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 7: Non-specific - Mitochondria" Cytosol "CAB018558: AB_2069454, HPA044999: AB_2679177" "unprognostic (5.35e-3)" "unprognostic (3.96e-1)" "unprognostic (4.99e-3)" "unprognostic (2.91e-2)" "unprognostic (1.07e-1)" "unprognostic (2.87e-2)" "unprognostic (1.99e-3)" "unprognostic (1.52e-1)" "unprognostic (6.44e-2)" "unprognostic (1.16e-3)" "prognostic favorable (5.62e-4)" "unprognostic (2.77e-1)" "prognostic favorable (6.49e-4)" "unprognostic (2.66e-1)" "unprognostic (2.68e-1)" "unprognostic (1.11e-2)" "prognostic unfavorable (2.38e-5)" 264.2 143.5 429.9 152.3 537.5 349.1 123.1 442.8 839.7 134.2 259.8 332.9 289.6 105.1 209.7 304.6 251.4 153.8 287.0 635.9 371.6 326.3 210.9 209.1 165.7 466.2 374.6 104.4 121.7 225.5 143.9 207.4 447.5 169.5 312.2 241.6 188.0 215.3 588.9 104.0 279.2 227.2 328.7 166.6 202.2 123.6 443.5 146.5 118.0 185.6 210.5 191.6 125.2 527.2 189.3 256.3 308.0 115.7 332.2 286.5 256.9 347.4 295.3 260.0 283.2 278.1 320.9 200.8 171.1 413.0 123.4 309.4 194.6 490.1 431.0 398.3 119.7 212.4 211.0 264.1 185.9 327.6 167.2 188.0 232.7 261.6 93.1 173.6 592.9 140.3 101.3 270.0 353.9 653.7 112.4 316.2 178.4 521.1 351.6 216.9 264.9 134.4 215.3 574.5 621.2 259.1 292.3 507.7 195.5 254.0 335.6 112.0 363.1 212.9 137.7 224.8 289.0 149.5 371.0 222.2 335.9 267.6 301.5 1289.6 356.8 826.7 1005.3 420.4 1230.3 496.8 1039.1 1079.6 483.1 400.2 745.7 882.7 513.3 1036.9 647.3 453.3 1168.3 1477.9 429.9 537.5 442.8 839.7 635.9 371.6 466.2 374.6 447.5 328.7 443.5 527.2 1812.3 387.8 374.4 119.8 573.2 567.1 572.2 604.2 543.5 1729.1 343.7 514.8 867.5 346.0 523.1 399.1 123.0 427.7 1471.8 828.8 459.7 550.8 154.9 1026.1 249.0 996.0 599.8 143.5 367.6 444.7 984.2 521.4 317.0 377.6 490.3 148.5 652.5 333.7 795.1 604.0 258.9 513.9 730.4 286.5 837.4 101.5 210.6 639.9 627.9 131.2 856.3 1061.8 1100.9 108.0 188.9 534.2 615.8 500.2 591.8 287.7 1637.2 1430.5 1618.4 321.1 315.5 387.5 901.6 128.8 199.8 553.8 580.4 1147.6 1139.3 247.8 666.6 458.5 CAMK1 "CaMKI, CaMKI-alpha" ENSG00000134072 "Calcium/calmodulin dependent protein kinase I" Q14012 3 9757347-9769992 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Differentiation, Neurogenesis" "Allosteric enzyme, Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 58.3;Hofbauer cells: 76.2;Macrophages: 71.2;Sertoli cells: 59.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "eosinophil: 280.5" "Lineage enriched" "Detected in many" 7 "granulocytes: 280.5" "Cell line enriched" "Detected in many" 4 "HMC-1: 403.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031904, HPA051409" Approved Approved Cytosol NA NA 110000 "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB031904: AB_630964, HPA051409: AB_2681473" "unprognostic (4.43e-2)" "unprognostic (3.05e-1)" "unprognostic (1.68e-1)" "unprognostic (1.29e-1)" "unprognostic (1.11e-1)" "unprognostic (3.06e-2)" "prognostic unfavorable (7.52e-4)" "unprognostic (5.53e-2)" "unprognostic (3.32e-1)" "unprognostic (9.74e-2)" "unprognostic (1.37e-3)" "unprognostic (2.17e-1)" "unprognostic (1.14e-3)" "unprognostic (7.76e-2)" "unprognostic (1.72e-1)" "unprognostic (3.67e-2)" "unprognostic (3.01e-1)" 52.4 99.7 50.1 17.2 48.9 5.1 37.2 39.9 61.0 27.0 31.8 33.6 9.2 31.8 13.7 8.0 37.0 11.1 20.5 61.2 46.3 24.9 36.4 23.9 11.1 37.8 41.7 41.2 8.4 14.4 21.6 6.7 38.8 31.1 10.6 5.9 9.8 19.7 7.1 7.9 16.5 26.0 36.8 16.7 21.7 29.8 46.9 4.3 19.5 7.8 15.0 28.4 18.3 46.1 0.5 16.4 12.6 0.0 64.7 24.3 32.6 38.4 21.1 43.1 40.4 24.1 3.0 1.1 9.0 26.0 6.2 2.7 0.0 5.0 27.0 0.4 95.4 53.5 32.1 34.1 35.9 4.5 403.3 25.3 4.1 60.6 6.7 35.4 36.8 0.9 7.2 1.2 16.3 10.3 0.3 38.8 9.0 0.4 25.7 0.3 0.4 1.1 25.9 2.8 4.2 16.7 6.6 0.7 4.0 5.3 4.1 67.2 19.6 19.8 24.4 28.0 48.7 0.4 0.3 1.0 41.5 14.7 3.0 17.8 21.3 280.5 0.3 42.2 0.1 0.1 0.4 0.2 14.1 0.2 0.3 0.1 1.0 3.6 43.0 0.4 2.0 4.7 50.1 48.9 39.9 61.0 61.2 46.3 37.8 41.7 38.8 36.8 46.9 46.1 58.3 0.0 3.1 17.9 2.8 5.0 19.2 3.4 5.7 9.9 5.2 4.6 0.1 12.8 2.1 11.0 2.1 0.4 3.0 2.6 9.8 14.4 1.8 1.8 14.9 22.8 6.0 4.8 25.6 4.0 1.2 23.3 5.6 3.1 30.5 16.7 30.4 23.5 76.2 0.0 14.5 2.3 0.0 46.4 40.2 7.2 36.1 71.2 5.4 8.4 36.7 39.4 3.1 6.6 2.7 5.5 2.9 45.1 0.2 17.5 3.6 47.4 1.3 7.7 59.2 12.2 42.7 1.5 3.7 1.5 3.8 0.8 7.1 6.6 7.6 11.0 CAMKK1 "CAMKKA, DKFZp761M0423, MGC34095" ENSG00000004660 "Calcium/calmodulin dependent protein kinase kinase 1" Q8N5S9 17 3860315-3894891 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 41.9;Excitatory neurons: 52.7;Rod photoreceptor cells: 25.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 21.5;basal ganglia: 24.2;cerebral cortex: 54.4;hippocampal formation: 24.8;white matter: 31.9" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 28.3;U-87 MG: 27.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009111, HPA028062" Approved Supported Cytosol No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "CAB009111: AB_2068406, HPA028062: AB_1845954" "unprognostic (1.39e-2)" "unprognostic (2.13e-1)" "unprognostic (8.66e-3)" "unprognostic (4.40e-3)" "unprognostic (2.94e-3)" "unprognostic (4.79e-2)" "unprognostic (1.98e-1)" "unprognostic (4.47e-3)" "unprognostic (8.23e-2)" "unprognostic (1.03e-2)" "prognostic favorable (2.65e-4)" "unprognostic (1.98e-1)" "unprognostic (1.59e-1)" "unprognostic (7.19e-2)" "unprognostic (8.70e-2)" "unprognostic (8.36e-2)" "unprognostic (3.10e-1)" 6.0 10.7 21.5 5.2 24.2 4.1 5.4 5.6 54.4 12.7 0.0 10.2 2.9 13.1 4.8 6.8 7.0 3.6 5.7 24.8 0.8 3.6 1.0 5.0 2.6 6.0 1.9 8.1 12.7 4.1 24.4 2.0 6.6 8.2 2.7 12.0 29.9 10.4 3.4 15.9 6.9 5.8 0.6 9.6 4.2 10.1 5.0 5.1 7.6 1.6 2.3 16.1 13.8 31.9 7.0 11.8 1.2 5.9 4.1 7.2 0.4 4.7 5.1 4.4 2.0 4.3 2.1 4.2 5.0 9.1 4.6 20.3 3.2 5.8 2.7 0.1 10.7 4.8 28.3 1.6 4.2 0.7 3.6 5.5 4.9 8.4 2.8 3.8 2.0 6.0 3.8 0.2 2.2 1.9 6.0 2.7 1.3 10.1 11.0 3.0 5.1 4.8 4.8 4.4 6.7 3.8 1.8 13.9 3.1 0.7 5.3 1.6 2.8 7.6 10.2 9.9 4.0 0.5 0.3 0.1 27.9 4.0 1.0 0.0 0.9 1.9 0.2 2.0 0.5 0.0 0.3 0.2 0.8 0.0 0.3 0.1 2.7 0.0 2.1 0.4 0.0 0.7 21.5 24.2 5.6 54.4 24.8 0.8 6.0 1.9 6.6 0.6 5.0 31.9 5.5 6.4 12.5 8.1 7.0 3.7 2.1 1.5 1.8 41.9 2.5 1.3 6.3 0.0 3.3 1.8 16.7 0.3 3.4 1.7 0.0 0.4 0.1 1.7 7.8 5.6 4.2 0.4 52.7 1.6 0.1 5.5 0.5 1.6 17.1 0.9 2.9 0.6 4.3 8.4 13.9 1.3 2.0 3.2 3.3 1.3 1.2 6.9 8.8 9.4 0.8 4.7 2.1 4.0 3.5 0.6 0.6 1.2 2.2 2.2 0.2 0.3 1.5 25.1 0.0 2.0 1.7 0.1 1.1 4.1 5.4 0.3 2.9 1.2 2.1 1.1 CAMKK2 "CAMKK, CAMKKB, KIAA0787, MGC15254" ENSG00000110931 "Calcium/calmodulin dependent protein kinase kinase 2" Q96RR4 12 121237675-121298308 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 135.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 64.8;Horizontal cells: 62.2;Late spermatids: 89.6" "Cancer enriched" "Detected in all" 5 "prostate cancer: 56.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 32.7;eosinophil: 62.1;intermediate monocyte: 42.3;myeloid DC: 15.9;neutrophil: 39.2;non-classical monocyte: 39.5" "Group enriched" "Detected in all" 5 "dendritic cells: 15.9;granulocytes: 62.1;monocytes: 42.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017389, HPA063713" Approved Supported Supported Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA017389: AB_1845956, HPA063713: " "unprognostic (5.08e-2)" "unprognostic (1.81e-1)" "unprognostic (1.38e-1)" "unprognostic (3.08e-1)" "unprognostic (1.88e-1)" "unprognostic (1.12e-1)" "unprognostic (2.62e-3)" "unprognostic (2.80e-2)" "unprognostic (1.93e-1)" "unprognostic (7.76e-2)" "unprognostic (5.01e-2)" "unprognostic (1.70e-1)" "unprognostic (1.75e-1)" "unprognostic (4.13e-1)" "unprognostic (3.34e-2)" "unprognostic (1.67e-1)" "unprognostic (1.38e-1)" 26.0 16.7 39.6 17.0 56.2 30.8 22.7 135.4 65.5 22.3 14.3 22.8 25.7 22.9 10.8 17.5 27.5 12.9 17.8 44.8 24.8 16.7 30.9 23.6 15.3 20.8 20.1 27.4 16.8 12.4 11.8 15.3 24.9 29.5 19.4 7.1 18.6 23.8 11.5 18.3 26.6 20.7 18.3 39.6 24.0 7.0 23.6 13.4 17.1 11.2 15.6 25.9 21.1 42.7 27.9 20.5 16.3 30.9 46.7 43.0 22.8 22.0 23.8 19.0 17.3 21.4 12.1 43.0 18.1 48.1 14.1 22.7 20.0 25.8 15.1 29.3 35.9 22.0 14.4 21.3 31.1 50.0 20.0 28.2 37.2 18.0 41.4 26.0 45.0 33.5 25.2 23.6 18.4 27.2 55.8 40.6 11.7 24.9 22.7 35.3 18.4 37.7 18.8 32.1 60.2 22.4 31.5 16.5 19.1 12.9 39.7 62.0 32.2 14.8 11.8 13.1 13.0 84.8 55.6 32.7 27.7 34.4 16.0 2.0 32.7 62.1 4.7 42.3 4.6 4.8 3.5 4.2 15.9 2.8 3.2 3.8 39.2 8.6 39.5 3.6 3.3 15.8 39.6 56.2 135.4 65.5 44.8 24.8 20.8 20.1 24.9 18.3 23.6 42.7 25.4 9.6 5.6 9.8 5.7 7.9 6.0 8.1 8.0 22.2 11.6 10.5 8.2 12.8 8.3 9.2 2.1 9.2 10.6 18.2 3.9 9.6 16.0 6.5 19.6 21.9 34.3 12.0 64.8 10.4 8.2 18.0 13.3 10.9 6.3 23.3 15.0 19.7 7.9 62.2 21.4 16.2 8.2 14.8 15.6 89.6 20.5 16.6 8.8 12.2 36.3 5.4 12.3 10.1 19.3 8.5 10.9 31.6 11.9 16.5 26.6 9.6 7.2 7.0 19.7 7.7 20.6 0.8 2.9 13.3 6.0 3.4 7.6 32.7 17.6 6.3 CAMTA1 KIAA0833 ENSG00000171735 "Calmodulin binding transcription activator 1" Q9Y6Y1 1 6785454-7769706 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036342, HPA036343" Approved Supported Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA036342: AB_2675072, HPA036343: AB_10671839" "unprognostic (1.11e-1)" "unprognostic (6.31e-2)" "unprognostic (5.80e-2)" "unprognostic (4.14e-3)" "unprognostic (3.10e-2)" "unprognostic (1.47e-2)" "prognostic unfavorable (5.25e-4)" "unprognostic (1.08e-2)" "unprognostic (3.59e-1)" "prognostic favorable (4.10e-4)" "unprognostic (3.90e-3)" "unprognostic (8.84e-2)" "unprognostic (1.35e-3)" "unprognostic (2.17e-2)" "unprognostic (9.19e-3)" "unprognostic (1.42e-1)" "unprognostic (9.03e-3)" 37.1 43.7 56.2 23.6 55.3 26.5 38.7 63.4 75.8 33.0 29.4 71.8 52.8 40.1 81.7 37.5 36.0 30.4 114.0 55.0 68.6 68.4 70.5 36.7 27.3 69.4 66.0 35.4 26.4 43.3 35.5 26.4 68.7 47.0 48.5 68.2 50.5 50.5 101.6 26.0 41.1 42.4 61.5 30.7 45.2 44.5 66.4 31.9 52.0 104.7 33.5 56.5 35.2 60.8 67.6 37.2 101.2 51.7 51.2 77.6 28.4 71.0 54.7 75.3 63.1 45.1 83.2 55.5 54.6 75.2 50.3 40.8 53.6 73.7 106.5 41.8 57.8 62.7 85.1 89.6 83.0 48.2 43.6 52.5 50.2 54.5 83.0 64.6 85.1 77.7 44.8 73.2 87.9 65.0 64.6 130.9 70.2 85.2 43.2 42.5 90.2 123.7 103.4 38.7 104.2 83.7 50.4 74.1 113.9 72.3 40.2 59.4 50.1 53.1 44.9 55.3 45.2 55.2 74.3 153.2 79.6 107.4 30.7 80.1 74.7 70.5 25.8 48.5 28.3 48.1 39.8 32.0 73.4 41.8 32.2 28.1 15.4 26.7 37.9 77.5 45.6 46.3 56.2 55.3 63.4 75.8 55.0 68.6 69.4 66.0 68.7 61.5 66.4 60.8 142.1 54.5 48.8 314.7 74.3 309.7 340.6 306.6 169.0 106.7 231.7 283.2 565.2 101.5 135.3 191.3 252.3 69.8 44.3 198.3 418.7 180.1 166.1 84.1 80.3 155.8 130.8 81.8 346.1 206.3 144.9 134.4 63.2 99.8 55.2 205.4 106.1 239.0 106.3 158.2 479.3 185.8 223.8 95.5 254.0 137.9 76.4 122.0 238.3 117.1 172.9 112.3 38.1 330.3 227.5 184.2 234.5 128.6 87.9 486.4 251.7 750.7 117.1 156.2 138.1 91.1 233.2 151.0 211.0 158.9 282.7 88.1 68.2 137.8 186.5 413.7 CAP1 CAP ENSG00000131236 "Cyclase associated actin cytoskeleton regulatory protein 1" Q01518 1 40040233-40072649 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 832.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "THP-1: 1954.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030124 Approved Approved Cytosol NA NA 73000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "HPA030124: AB_10600799" "unprognostic (1.80e-3)" "unprognostic (1.23e-3)" "unprognostic (5.68e-2)" "unprognostic (1.04e-1)" "unprognostic (6.50e-2)" "unprognostic (1.37e-2)" "prognostic unfavorable (1.44e-6)" "unprognostic (5.37e-2)" "unprognostic (4.87e-1)" "unprognostic (1.98e-1)" "unprognostic (3.33e-3)" "unprognostic (1.09e-1)" "unprognostic (6.22e-2)" "unprognostic (1.39e-1)" "unprognostic (7.08e-2)" "unprognostic (1.26e-1)" "unprognostic (3.44e-1)" 175.2 96.8 78.6 275.0 92.3 314.9 137.5 87.6 95.3 131.2 77.8 223.7 143.7 207.2 100.4 196.2 134.2 135.3 82.3 82.6 85.3 130.7 124.4 181.7 266.8 98.0 87.6 87.7 67.8 115.1 62.8 184.2 94.4 105.0 210.4 63.4 117.4 140.1 48.1 120.2 165.0 236.6 89.7 206.1 147.8 75.0 91.5 186.8 106.8 56.0 326.4 231.2 130.4 107.9 435.9 185.1 216.4 134.8 310.6 290.5 338.9 749.8 437.7 398.9 399.9 272.5 440.1 339.5 295.7 598.7 275.7 267.1 265.8 535.7 548.1 461.6 164.9 520.2 188.7 216.8 286.4 326.9 1417.9 297.5 280.6 612.5 345.4 456.5 346.4 185.7 201.6 215.0 621.7 129.2 265.4 194.9 367.7 312.1 207.9 197.0 297.6 198.6 451.3 452.0 107.5 222.9 308.7 366.4 523.8 443.1 170.0 1954.7 628.9 347.3 317.9 188.0 641.4 178.9 381.8 301.0 451.5 353.8 466.9 1371.5 776.8 2592.7 665.8 1097.6 526.2 328.0 473.4 643.9 868.3 325.6 397.1 537.9 1560.4 479.8 1402.6 333.8 701.5 1838.4 78.6 92.3 87.6 95.3 82.6 85.3 98.0 87.6 94.4 89.7 91.5 107.9 132.5 121.8 90.9 17.6 179.0 112.3 149.0 236.2 48.9 40.8 81.8 89.9 15.7 80.1 161.8 114.0 27.1 212.9 206.9 372.1 111.6 364.1 411.3 94.5 109.8 163.2 76.1 73.4 22.3 272.3 439.6 107.9 74.5 182.9 229.1 70.9 167.0 77.0 426.0 42.1 16.7 180.2 142.4 411.6 333.3 480.3 88.0 390.8 99.6 25.3 606.5 160.9 315.1 13.0 30.4 832.7 202.0 176.8 117.1 130.7 159.7 142.1 105.6 49.5 164.3 68.9 207.1 118.0 67.9 97.2 132.8 237.8 238.0 74.8 151.5 221.4 CAPN1 "CANP, CANPL1, muCANP, muCL" ENSG00000014216 "Calpain 1" P07384 11 65180566-65212006 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 276.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 516.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005992 Enhanced Supported Cytosol NA NA 9100000 "Cluster 46: Basophils - DNA binding" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA005992: AB_1845924" "unprognostic (2.07e-1)" "unprognostic (2.15e-1)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (4.06e-2)" "unprognostic (1.10e-1)" "unprognostic (1.91e-2)" "unprognostic (2.48e-2)" "unprognostic (7.23e-2)" "unprognostic (2.23e-2)" "prognostic unfavorable (4.30e-4)" "unprognostic (3.33e-1)" "prognostic favorable (7.06e-8)" "unprognostic (5.70e-3)" "unprognostic (1.51e-1)" "unprognostic (1.86e-1)" "unprognostic (2.98e-1)" 44.8 43.1 27.8 51.9 26.1 66.5 48.4 29.7 30.1 80.9 28.3 78.6 80.4 56.3 27.5 276.2 92.3 55.5 53.1 27.7 33.0 53.1 44.3 56.9 57.0 41.4 31.5 44.5 71.7 36.6 40.8 56.2 43.4 62.1 57.6 9.6 118.7 67.4 84.8 125.1 88.1 45.3 33.9 50.2 65.5 6.1 37.9 49.5 71.5 55.3 86.4 83.4 117.4 27.4 285.6 147.9 42.9 97.2 77.9 104.3 127.0 84.1 144.2 103.0 74.9 94.8 250.2 71.2 136.0 179.3 111.1 409.8 60.9 366.9 32.2 76.4 44.1 170.8 80.4 93.7 76.2 40.6 228.0 107.3 196.8 85.9 43.2 92.6 178.5 50.6 103.1 55.9 87.4 181.8 83.1 130.6 120.5 145.2 133.8 80.7 43.0 43.2 138.1 516.5 76.2 55.7 87.4 331.4 80.3 45.8 142.8 77.9 147.1 73.1 50.5 159.0 38.5 33.8 26.9 86.6 127.5 48.8 82.3 87.6 57.5 77.9 39.4 51.2 31.0 30.8 30.7 35.8 48.4 31.7 17.6 24.9 33.1 34.8 30.4 38.1 35.9 74.8 27.8 26.1 29.7 30.1 27.7 33.0 41.4 31.5 43.4 33.9 37.9 27.4 27.3 25.6 27.9 21.5 39.6 59.9 127.3 120.5 56.9 10.7 44.7 36.6 22.0 74.4 81.0 77.3 20.9 238.5 61.4 184.2 39.2 180.5 0.5 41.9 26.3 31.3 44.3 58.3 15.9 115.8 111.7 39.6 57.6 58.2 46.9 48.6 37.9 36.7 88.7 21.9 15.2 76.9 59.0 51.2 34.0 2.0 43.5 67.1 48.0 14.0 112.7 38.5 61.8 6.6 1.9 179.4 124.1 50.8 17.7 78.6 155.6 34.6 71.1 16.2 39.5 25.3 36.7 0.5 2.8 102.0 68.9 196.6 40.2 35.4 125.3 156.6 CAPN2 "CANPL2, CANPml, mCANP" ENSG00000162909 "Calpain 2" P17655 1 223701593-223776018 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "TIME: 858.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024470 Approved Approved Supported Cytosol NA NA 2800000 "Cluster 39: Non-specific - mRNA processing" "Cluster 46: Fibroblasts - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "HPA024470: AB_1845925" "unprognostic (2.77e-2)" "unprognostic (1.27e-3)" "unprognostic (2.03e-1)" "unprognostic (3.39e-2)" "unprognostic (2.12e-1)" "unprognostic (3.32e-2)" "unprognostic (1.59e-1)" "unprognostic (1.10e-1)" "unprognostic (2.85e-1)" "unprognostic (1.96e-1)" "prognostic unfavorable (2.50e-4)" "unprognostic (1.21e-1)" "prognostic favorable (2.19e-4)" "unprognostic (1.61e-1)" "unprognostic (2.63e-1)" "unprognostic (2.62e-1)" "prognostic unfavorable (6.21e-4)" 118.8 93.9 40.2 64.9 50.0 40.9 92.4 45.3 39.6 110.4 29.4 140.1 46.2 67.7 58.0 134.3 120.5 119.7 71.8 36.9 42.7 115.2 31.2 182.5 35.5 51.9 46.1 83.2 55.1 136.3 28.0 68.3 46.6 47.5 131.4 19.2 151.2 91.2 82.2 41.6 58.5 87.3 43.4 42.5 130.4 26.3 49.1 27.0 80.9 81.6 54.3 85.6 89.3 49.3 419.9 263.7 79.2 54.9 257.6 356.6 79.4 383.9 541.3 267.2 151.1 209.2 323.6 0.4 125.0 417.1 209.1 255.1 86.3 593.1 243.4 109.8 95.2 7.8 124.9 25.6 232.3 21.5 13.9 193.3 187.3 416.6 217.8 472.3 537.1 0.1 123.2 106.8 789.3 8.6 1.0 19.4 45.5 49.7 346.3 35.4 262.4 7.3 454.9 24.3 17.7 94.7 198.1 524.2 122.8 189.7 80.9 98.7 858.1 252.7 212.0 220.6 498.4 32.5 66.8 1.4 625.3 46.2 284.7 7.9 118.6 7.2 106.8 77.9 89.8 34.4 72.6 103.2 163.9 16.6 22.9 62.2 6.1 24.5 73.7 7.4 81.7 136.6 40.2 50.0 45.3 39.6 36.9 42.7 51.9 46.1 46.6 43.4 49.1 49.3 240.0 394.2 134.9 82.9 42.3 47.3 136.6 197.5 38.7 12.0 35.7 32.8 38.4 115.8 264.4 53.3 33.3 24.4 72.4 356.0 181.9 271.4 94.5 70.0 52.7 125.3 24.6 6.9 13.3 195.9 92.0 105.0 103.5 93.3 27.8 47.8 35.7 9.7 38.9 13.5 23.1 104.4 242.1 50.0 239.3 232.8 77.3 86.4 112.1 22.5 66.0 22.6 78.2 48.7 21.6 373.0 191.5 68.8 83.3 237.7 104.1 23.6 288.8 18.0 39.5 85.0 107.9 3.4 3.3 67.5 27.6 8.2 83.5 63.5 98.2 268.2 CAPNS2 "MGC12536, MGC14804" ENSG00000256812 "Calpain small subunit 2" Q96L46 16 55566684-55567687 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 85.7;skin 1: 102.4" "Group enriched" "Detected in some" 7 "Basal keratinocytes: 87.8;Basal squamous epithelial cells: 117.3;Squamous epithelial cells: 108.6;Suprabasal keratinocytes: 149.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 26.3;urothelial cancer: 21.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "eosinophil: 3.8;intermediate monocyte: 1.0" "Group enriched" "Detected in many" 9 "granulocytes: 3.8;monocytes: 1.0" "Cell line enriched" "Detected in some" 10 "hTCEpi: 223.0" "Not detected" "Not detected" "HPA059749, HPA076768" Enhanced Approved Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA059749: AB_2732639, HPA076768: AB_2732322" "unprognostic (3.26e-2)" "unprognostic (6.85e-2)" "unprognostic (2.57e-1)" "unprognostic (1.77e-3)" "unprognostic (4.14e-1)" "unprognostic (3.32e-2)" "unprognostic (1.79e-1)" "unprognostic (2.98e-1)" "unprognostic (7.21e-2)" "unprognostic (3.38e-2)" "unprognostic (3.62e-1)" "unprognostic (2.42e-2)" "unprognostic (4.48e-1)" "unprognostic (4.11e-2)" "unprognostic (2.82e-1)" "unprognostic (1.69e-1)" 0.4 0.0 0.4 0.1 0.7 0.6 6.6 0.9 0.5 14.3 0.4 0.0 0.0 0.1 0.2 85.7 0.8 0.0 0.1 0.5 0.6 0.0 0.1 0.2 0.0 1.5 0.9 0.1 0.1 0.0 0.1 0.3 1.6 4.2 0.0 0.1 16.8 0.1 0.7 102.4 0.1 0.0 1.1 0.1 0.1 0.0 1.1 0.2 0.3 0.0 18.6 18.1 33.5 1.5 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.0 23.0 0.0 1.0 0.1 0.1 0.1 0.2 0.0 0.1 0.0 0.7 0.8 0.0 223.0 0.0 0.0 0.6 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.1 0.0 1.1 0.1 7.6 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.5 1.2 0.0 0.1 3.8 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.4 0.7 0.9 0.5 0.5 0.6 1.5 0.9 1.6 1.1 1.1 1.5 0.6 0.0 0.5 0.0 0.0 87.8 10.0 13.7 117.3 0.0 0.2 0.3 0.0 0.0 11.9 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.1 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.1 0.8 7.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.5 0.7 0.0 0.0 108.6 149.3 2.3 0.2 0.1 0.0 15.4 CAPRIN1 "caprin-1, GPIAP1, M11S1, RNG105" ENSG00000135387 "Cell cycle associated protein 1" Q14444 11 34051731-34102610 "Predicted intracellular proteins" Differentiation "Protein synthesis inhibitor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 483.0;Late spermatids: 289.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018126, HPA063617" Approved Enhanced Cytosol NA NA 43000 "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" Cytosol "HPA018126: AB_1849929, HPA063617: AB_2685062" "unprognostic (3.79e-1)" "unprognostic (3.85e-2)" "unprognostic (3.51e-3)" "unprognostic (1.12e-1)" "unprognostic (2.28e-1)" "unprognostic (1.97e-2)" "prognostic unfavorable (8.67e-8)" "unprognostic (3.79e-1)" "unprognostic (3.12e-2)" "unprognostic (1.13e-1)" "unprognostic (1.93e-3)" "unprognostic (2.90e-1)" "unprognostic (2.87e-2)" "unprognostic (2.55e-1)" "unprognostic (1.37e-2)" "unprognostic (1.22e-1)" "unprognostic (1.22e-1)" 45.2 30.6 26.1 42.2 28.6 70.3 56.8 25.0 30.9 56.8 21.8 48.8 46.0 52.7 30.5 47.1 61.8 41.7 44.9 28.7 28.3 49.9 39.9 43.3 42.9 26.1 26.7 60.5 47.5 59.9 21.6 53.8 27.3 45.7 60.5 58.7 38.6 53.5 45.3 30.3 41.1 66.2 32.3 40.1 42.1 123.0 26.9 77.6 53.3 54.0 62.6 58.9 31.8 36.7 134.7 168.8 245.6 137.2 180.9 182.5 117.5 168.0 175.8 202.4 188.2 154.9 80.8 211.1 104.9 213.9 169.4 173.1 311.9 204.3 244.9 134.7 155.5 174.1 153.3 131.9 109.4 282.0 122.8 164.0 109.2 129.1 236.3 174.7 204.2 153.7 228.1 103.6 211.3 114.5 243.7 55.8 114.8 155.3 150.6 191.8 339.2 93.7 120.4 263.1 155.5 147.7 202.6 101.1 88.8 150.5 183.5 104.4 205.3 172.7 116.4 167.9 190.8 110.9 175.5 238.7 117.2 116.3 191.7 25.0 33.3 13.9 18.8 39.7 27.3 19.4 20.9 23.2 39.0 17.8 21.6 21.1 13.5 30.7 43.4 18.2 28.1 31.0 26.1 28.6 25.0 30.9 28.7 28.3 26.1 26.7 27.3 32.3 26.9 36.7 42.1 35.3 43.5 37.9 46.0 77.8 45.5 51.5 68.9 38.1 63.7 43.9 55.4 24.3 37.2 64.4 18.8 46.7 47.2 46.0 31.3 56.6 483.0 90.0 116.5 52.1 71.8 79.0 37.4 60.1 60.2 54.6 65.7 132.2 17.1 63.1 39.7 46.1 57.2 25.2 38.8 51.1 54.9 75.8 72.3 289.3 47.8 57.9 39.2 37.5 57.0 36.7 35.0 44.2 53.1 71.3 40.4 72.6 83.0 72.7 42.9 47.4 49.5 32.3 39.5 40.4 64.3 201.7 74.8 93.2 72.9 45.8 46.5 53.9 65.5 77.7 CAPZA2 "CAPPA2, CAPZ" ENSG00000198898 "Capping actin protein of muscle Z-line subunit alpha 2" P47755 7 116811070-116922049 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007470, HPA007643" Uncertain Approved Cytosol No No 4500000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA007470: AB_1845985, HPA007643: AB_2667886" "unprognostic (1.37e-2)" "unprognostic (2.25e-3)" "unprognostic (4.16e-2)" "unprognostic (3.16e-1)" "unprognostic (1.53e-1)" "unprognostic (2.63e-3)" "prognostic unfavorable (9.34e-5)" "unprognostic (1.90e-2)" "unprognostic (1.80e-2)" "unprognostic (2.15e-1)" "unprognostic (2.08e-3)" "unprognostic (2.52e-1)" "prognostic favorable (3.65e-6)" "unprognostic (1.40e-1)" "unprognostic (1.08e-1)" "unprognostic (2.91e-3)" "unprognostic (6.58e-2)" 26.3 20.1 17.0 20.0 17.3 43.3 21.8 22.5 25.8 18.0 16.9 24.4 20.4 19.7 19.0 20.8 14.2 20.7 45.7 21.3 17.5 37.3 33.9 23.8 20.1 17.0 17.1 12.6 13.4 19.4 7.5 24.9 20.5 20.3 23.9 13.4 14.6 20.5 64.3 12.3 23.4 28.1 14.5 22.3 20.0 8.7 19.6 16.4 22.8 53.1 17.3 28.1 11.3 18.3 30.0 19.5 19.8 25.2 35.9 37.8 9.8 28.7 41.3 28.8 32.7 14.5 38.1 20.8 46.5 41.3 36.1 18.2 20.4 24.1 45.4 22.7 14.9 31.3 18.0 24.6 22.2 21.2 40.9 30.2 26.9 22.9 21.9 34.8 63.2 12.9 20.8 35.2 57.9 13.0 28.3 35.6 29.5 31.3 16.8 19.7 26.2 42.1 69.3 24.6 20.6 23.5 27.7 104.1 29.7 25.0 14.5 25.0 23.0 47.0 14.6 37.5 28.5 27.7 21.0 39.6 28.0 29.6 34.0 57.3 34.8 45.6 11.1 45.6 13.2 14.4 13.5 11.9 33.2 12.6 12.9 13.1 69.4 15.9 54.9 18.1 18.1 45.3 17.0 17.3 22.5 25.8 21.3 17.5 17.0 17.1 20.5 14.5 19.6 18.3 177.9 73.7 67.4 44.4 109.4 243.1 219.8 224.3 94.4 106.6 85.1 67.3 219.4 71.4 146.5 171.0 27.1 151.7 96.2 147.4 516.5 193.1 9.6 139.4 113.7 189.5 121.2 263.9 59.2 160.3 204.0 124.8 103.5 340.1 126.2 48.8 262.3 110.6 314.1 107.7 48.0 102.6 286.8 238.5 274.9 16.2 74.6 262.9 181.5 64.6 222.4 164.5 72.1 49.8 47.1 193.1 147.5 110.9 83.0 140.9 182.6 519.7 99.7 95.9 92.1 122.8 188.9 43.1 47.0 94.1 218.8 144.1 108.6 78.7 109.9 207.0 CARMIL1 "CARMIL, dJ501N12.1, FLJ20048, LRRC16, LRRC16A" ENSG00000079691 "Capping protein regulator and myosin 1 linker 1" Q5VZK9 6 25279078-25620530 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 27.9;Collecting duct cells: 35.0;Distal tubular cells: 46.9;Endometrial ciliated cells: 37.3;Glandular and luminal cells: 39.3;Granulosa cells: 31.8;Proximal tubular cells: 58.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPMI-8226: 36.0;RPTEC TERT1: 34.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029038, HPA029039" Enhanced Supported Cytosol NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA029038: AB_10601668, HPA029039: AB_10611382" "unprognostic (2.34e-2)" "unprognostic (9.45e-2)" "unprognostic (2.07e-2)" "unprognostic (4.71e-2)" "unprognostic (3.94e-2)" "unprognostic (2.22e-1)" "unprognostic (1.66e-3)" "unprognostic (3.82e-1)" "unprognostic (4.02e-1)" "unprognostic (7.15e-3)" "unprognostic (8.25e-3)" "unprognostic (5.86e-2)" "unprognostic (1.28e-3)" "unprognostic (3.08e-2)" "unprognostic (2.53e-1)" "unprognostic (1.07e-1)" "unprognostic (2.31e-1)" 4.4 3.9 2.7 2.8 4.1 0.7 6.5 6.4 5.9 5.2 0.0 10.7 15.3 2.5 7.1 4.3 5.5 5.8 3.7 2.2 2.5 8.5 2.1 8.0 3.6 1.0 3.5 4.3 4.5 5.1 1.2 4.6 0.8 3.3 10.0 1.0 5.3 2.7 0.4 5.9 15.8 2.7 1.3 2.8 7.4 11.4 3.2 7.6 5.2 2.0 3.7 5.2 3.7 1.2 12.9 12.7 3.5 4.5 3.2 1.6 12.1 4.3 9.7 4.5 7.9 13.7 9.4 4.4 13.8 6.9 13.2 13.7 13.6 12.2 3.3 11.1 7.2 10.7 14.0 1.7 8.9 0.5 1.6 1.7 8.2 8.7 13.3 5.6 0.2 1.6 0.3 3.5 2.9 10.0 0.7 0.0 4.8 22.7 5.2 1.5 2.1 36.0 34.7 11.5 9.0 1.9 19.1 32.4 12.4 10.1 7.8 0.3 0.2 3.3 5.8 15.8 4.4 0.5 0.2 7.0 5.2 3.9 12.6 0.0 0.4 0.0 0.0 0.5 0.0 0.2 0.1 0.1 0.4 1.3 1.0 0.1 0.0 0.6 1.3 0.9 0.0 0.1 2.7 4.1 6.4 5.9 2.2 2.5 1.0 3.5 0.8 1.3 3.2 1.2 3.2 19.2 27.9 0.0 7.7 0.0 0.0 0.0 0.0 0.0 17.5 11.6 0.0 0.0 4.3 35.0 0.0 20.8 0.4 0.0 46.9 16.7 0.0 37.3 7.0 4.0 0.0 0.0 0.0 15.6 7.9 12.8 0.0 39.3 8.8 31.8 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 3.6 0.0 0.0 0.0 0.0 17.6 0.0 0.0 7.6 0.0 0.0 58.8 3.6 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 10.9 1.6 14.9 0.0 0.0 CARS1 CARS ENSG00000110619 "Cysteinyl-tRNA synthetase 1" P49589 11 3000922-3057613 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Cancer-related genes, Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 10.3;Cardiomyocytes: 8.8;Cytotrophoblasts: 22.2;Extravillous trophoblasts: 40.7;Hofbauer cells: 22.0;Syncytiotrophoblasts: 32.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002383, HPA002384, CAB075734, CAB075735, CAB075736, CAB075737" Enhanced Enhanced Cytosol NA NA 200000 "Cluster 14: Monocytes - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "CAB075734: AB_2665740, CAB075735: AB_2665741, CAB075736: AB_2665742, CAB075737: AB_2665743, HPA002383: AB_1078399, HPA002384: AB_1846033" "unprognostic (9.10e-3)" "unprognostic (1.83e-1)" "unprognostic (4.16e-3)" "unprognostic (1.43e-1)" "unprognostic (1.00e-2)" "unprognostic (7.97e-2)" "prognostic unfavorable (5.16e-4)" "unprognostic (1.41e-2)" "unprognostic (1.05e-1)" "unprognostic (8.00e-2)" "unprognostic (5.51e-2)" "unprognostic (2.45e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.37e-2)" "unprognostic (1.71e-1)" "unprognostic (1.48e-1)" "unprognostic (3.46e-1)" 22.1 17.4 8.1 12.0 8.5 7.3 19.9 8.7 21.6 13.6 8.4 21.8 12.0 15.9 7.5 19.2 12.8 10.3 13.3 8.2 9.8 13.7 21.1 17.5 12.7 9.6 9.9 8.9 32.8 9.6 18.6 10.3 10.6 12.7 12.8 5.3 20.6 6.8 31.7 23.8 17.4 16.0 9.7 17.2 23.5 16.8 9.9 14.6 17.3 14.7 17.8 18.1 14.9 11.5 29.2 14.0 17.8 55.6 67.3 61.4 16.2 70.0 78.6 46.7 84.1 34.2 64.7 43.1 20.1 88.2 0.0 68.7 58.3 78.6 64.0 123.7 13.5 24.4 23.7 25.8 161.1 50.9 50.2 102.2 64.1 40.1 46.8 0.0 62.3 103.6 42.2 147.0 47.1 41.9 35.7 0.0 65.2 97.9 25.0 17.2 29.7 54.9 0.0 46.1 39.0 49.7 17.1 48.1 80.1 13.3 0.0 0.1 21.8 19.5 18.2 48.2 0.2 107.8 106.8 27.2 0.1 26.6 40.3 16.3 18.6 13.5 20.9 15.4 17.4 10.9 18.3 18.6 19.4 8.5 9.9 16.0 25.4 23.7 37.9 7.5 27.0 19.2 8.1 8.5 8.7 21.6 8.2 9.8 9.6 9.9 10.6 9.7 9.9 11.5 10.3 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 22.2 8.1 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 40.7 3.7 0.0 0.0 0.0 0.0 0.0 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 32.3 1.4 0.0 0.0 0.0 CBL "c-Cbl, CBL2, RNF55" ENSG00000110395 "Cbl proto-oncogene" P22681 11 119206298-119313926 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 8.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004350, HPA027956" Enhanced Approved Cytosol NA NA 67000 "Cluster 1: Neutrophils - Mixed function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "CAB004350: AB_2244054, HPA027956: AB_10601094" "unprognostic (2.52e-1)" "unprognostic (1.32e-3)" "unprognostic (1.60e-1)" "unprognostic (1.15e-1)" "unprognostic (1.50e-2)" "unprognostic (2.92e-1)" "unprognostic (4.10e-3)" "unprognostic (9.75e-2)" "unprognostic (1.72e-1)" "unprognostic (1.52e-1)" "unprognostic (1.03e-2)" "unprognostic (5.23e-2)" "unprognostic (5.21e-2)" "unprognostic (5.27e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (5.85e-2)" 6.8 4.0 5.6 9.5 5.7 8.5 5.6 5.3 6.5 5.0 0.2 6.2 3.9 6.5 3.4 5.6 5.6 3.9 4.1 5.3 8.1 4.4 2.7 7.9 10.7 5.8 6.3 3.7 3.8 6.1 2.9 6.4 6.5 4.0 5.0 8.3 3.6 4.6 2.5 5.2 6.6 7.4 5.2 9.9 5.2 18.2 7.9 22.5 4.1 3.2 11.2 5.8 4.9 6.0 10.7 7.6 26.6 16.7 7.8 9.2 16.0 11.2 11.4 10.8 10.2 16.7 12.6 25.1 10.0 14.0 21.7 15.2 18.4 9.4 22.7 14.8 4.7 26.4 6.2 5.1 9.5 30.3 27.9 8.1 10.1 26.7 28.4 11.1 26.3 23.7 21.7 9.9 19.1 11.3 16.2 17.0 14.0 9.2 8.8 17.5 13.5 4.6 9.3 8.2 3.7 11.3 20.9 8.8 7.3 18.1 9.4 24.8 22.8 16.0 11.5 11.6 14.7 3.3 5.3 19.9 6.7 25.4 11.9 0.8 2.4 2.0 0.9 2.8 0.8 1.5 1.1 0.9 2.6 1.2 1.2 1.3 8.6 0.4 2.5 1.4 1.0 0.9 5.6 5.7 5.3 6.5 5.3 8.1 5.8 6.3 6.5 5.2 7.9 6.0 23.2 9.6 8.3 23.5 23.2 18.0 5.9 7.5 19.4 14.0 13.6 11.7 8.8 5.7 6.0 11.0 45.9 6.3 24.0 7.6 1.9 6.1 28.2 9.9 19.6 23.2 8.4 5.7 38.5 6.7 10.5 9.4 9.2 16.8 3.8 20.8 20.0 3.1 16.0 13.5 39.1 4.9 2.0 59.1 43.2 42.0 7.8 41.2 16.0 45.0 46.8 13.2 22.6 26.2 19.6 10.6 11.6 12.8 19.7 8.0 5.1 5.4 4.8 33.3 26.3 11.6 22.7 38.0 36.2 18.5 21.9 7.0 24.9 10.6 5.1 10.9 CCDC103 "CILD17, FLJ13094, FLJ34211, PR46b" ENSG00000167131 "Coiled-coil domain containing 103" Q8IW40 17 44899142-44905390 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "fallopian tube: 15.1;testis: 27.2" "Cell type enriched" "Detected in some" 5 "Respiratory ciliated cells: 7.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 14.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA043131 Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA043131: AB_10796686" "unprognostic (9.40e-3)" "unprognostic (1.75e-1)" "unprognostic (5.60e-2)" "unprognostic (1.99e-2)" "unprognostic (4.50e-2)" "unprognostic (7.43e-2)" "unprognostic (2.80e-1)" "unprognostic (2.34e-1)" "unprognostic (1.27e-1)" "unprognostic (4.35e-2)" "unprognostic (4.69e-1)" "unprognostic (1.05e-1)" "unprognostic (3.60e-1)" 0.3 1.2 1.3 0.5 1.6 0.4 0.5 1.1 1.4 1.1 2.6 0.6 0.3 1.2 1.5 0.2 15.1 0.8 0.2 1.3 1.6 1.7 0.4 1.5 0.1 2.7 3.9 0.8 0.5 1.4 0.9 0.3 2.0 0.4 0.3 1.9 0.3 1.1 0.3 0.3 0.2 0.9 2.0 0.2 0.5 27.2 1.8 0.4 1.8 0.0 0.2 0.3 0.3 1.3 2.5 14.4 1.4 2.4 2.3 1.6 1.3 1.0 2.5 1.3 0.8 2.9 3.3 0.3 2.0 0.7 5.7 3.5 0.5 1.7 0.6 6.9 4.9 0.8 3.3 0.1 1.2 1.7 0.4 1.1 3.2 1.6 0.6 2.4 1.1 1.1 1.9 0.2 0.3 2.0 0.3 0.6 0.5 1.8 2.3 0.5 0.7 0.7 6.6 1.3 4.1 1.0 0.6 0.3 1.8 1.3 3.7 1.4 1.6 0.8 2.8 0.8 2.0 0.6 0.7 0.7 7.0 0.8 0.7 0.4 1.6 1.3 0.2 0.9 0.1 0.1 0.0 0.3 1.1 0.3 0.1 0.1 0.2 0.4 0.8 0.4 0.0 1.0 1.3 1.6 1.1 1.4 1.3 1.6 2.7 3.9 2.0 2.0 1.8 1.3 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 7.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CCDC153 LOC283152 ENSG00000248712 "Coiled-coil domain containing 153" Q494R4 11 119189638-119196769 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 11.1" "Group enriched" "Detected in many" 7 "Endometrial ciliated cells: 92.3;Respiratory ciliated cells: 186.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 4.0;neutrophil: 15.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 15.8" "Cell line enhanced" "Detected in some" "CAPAN-2: 4.8;EFO-21: 4.2;HEL: 5.0;T-47d: 8.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA041497 Uncertain Uncertain Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA041497: AB_10794378" "unprognostic (4.66e-2)" "unprognostic (1.86e-2)" "unprognostic (3.88e-2)" "unprognostic (1.45e-2)" "unprognostic (1.53e-1)" "unprognostic (3.22e-2)" "unprognostic (6.87e-2)" "unprognostic (2.23e-3)" "unprognostic (5.19e-2)" "unprognostic (9.43e-3)" "unprognostic (1.36e-1)" "unprognostic (2.36e-1)" "unprognostic (2.92e-3)" "unprognostic (1.15e-1)" "unprognostic (3.80e-1)" "unprognostic (1.52e-3)" "unprognostic (1.98e-3)" 1.1 0.7 1.5 0.5 1.2 2.5 0.7 2.7 1.6 0.9 2.7 0.7 0.3 0.8 0.2 1.0 11.1 1.1 0.3 1.3 1.6 1.3 0.4 1.5 0.3 2.0 1.9 0.2 0.3 2.8 3.3 0.9 1.4 0.4 0.5 1.5 0.5 1.1 0.4 0.7 0.6 0.5 1.7 0.5 1.1 1.8 2.0 0.3 0.8 0.0 0.2 0.4 0.5 1.8 0.6 0.9 0.9 1.0 0.2 0.1 2.8 0.6 1.1 0.4 0.5 1.9 4.8 0.2 4.2 0.2 1.3 0.5 0.3 1.1 0.1 1.1 0.6 5.0 0.4 0.3 0.7 0.6 0.3 0.5 0.7 1.2 0.3 1.4 1.2 0.6 0.7 0.9 0.1 3.4 0.3 0.7 0.3 1.2 1.0 0.7 0.1 0.3 0.4 0.8 1.0 0.2 1.3 0.8 0.7 0.3 8.8 1.4 1.2 0.7 0.5 0.3 0.4 0.4 0.5 0.2 0.3 0.2 0.3 0.5 2.3 4.0 0.3 1.6 0.1 0.3 0.2 0.4 1.7 0.3 0.5 0.4 15.8 0.2 1.6 1.7 0.4 0.8 1.5 1.2 2.7 1.6 1.3 1.6 2.0 1.9 1.4 1.7 2.0 1.8 4.4 0.0 6.1 0.0 0.6 2.8 1.7 14.9 1.8 0.4 2.3 2.2 0.4 1.5 19.8 7.3 0.0 4.3 0.7 5.3 0.0 1.1 3.5 92.3 1.9 3.3 1.8 0.0 0.5 2.0 3.5 2.1 4.6 2.3 0.0 1.5 3.3 1.8 3.6 0.0 0.4 4.2 12.2 4.6 5.5 7.0 0.3 2.7 3.6 1.0 4.5 0.8 1.0 0.0 0.6 1.1 11.3 2.6 3.0 1.0 3.3 4.8 186.9 2.0 6.6 0.7 9.9 5.9 4.0 1.6 2.3 3.3 0.6 0.5 2.9 2.7 CCDC167 "C6orf129, dJ153P14.2" ENSG00000198937 "Coiled-coil domain containing 167" Q9P0B6 6 37482938-37499893 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 281.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "B-cells: 145.2;granulocytes: 140.2;T-cells: 423.5" "Cell line enriched" "Detected in all" 9 "U-698: 1553.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045215 Uncertain Approved Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA045215: AB_10962866" "unprognostic (1.82e-1)" "prognostic favorable (7.59e-4)" "unprognostic (6.99e-2)" "unprognostic (3.66e-1)" "unprognostic (2.86e-1)" "unprognostic (2.07e-1)" "prognostic unfavorable (2.94e-4)" "unprognostic (2.73e-1)" "unprognostic (7.67e-2)" "unprognostic (3.41e-3)" "unprognostic (2.71e-1)" "unprognostic (2.79e-1)" "prognostic unfavorable (1.71e-7)" "unprognostic (1.57e-1)" "unprognostic (4.06e-1)" "unprognostic (2.44e-1)" "unprognostic (1.95e-1)" 13.2 19.2 49.8 22.8 52.1 28.3 18.5 52.7 54.2 22.1 49.0 19.9 11.6 15.8 45.1 26.6 21.3 11.9 34.9 49.0 51.0 22.0 56.4 13.3 49.5 53.4 51.1 8.5 19.1 27.2 15.0 15.4 52.9 22.8 23.5 14.4 22.6 13.5 21.4 13.4 14.4 31.6 53.0 28.3 15.0 37.7 51.9 90.7 15.1 26.2 70.3 16.8 17.1 57.7 27.2 61.9 137.1 95.4 37.4 65.5 50.4 31.6 25.8 48.8 54.5 66.1 39.5 146.9 69.4 54.8 92.1 20.7 90.4 74.1 49.7 122.9 166.9 69.7 25.3 168.7 39.1 68.4 26.4 30.7 153.4 52.1 47.4 34.2 154.0 150.2 44.1 123.1 85.1 90.2 129.1 56.6 8.0 76.7 39.3 79.0 48.4 108.9 66.3 53.6 93.3 109.6 47.1 46.0 74.3 119.3 50.1 70.3 38.5 31.8 61.6 17.8 32.5 89.3 97.1 1553.2 30.8 147.9 90.8 34.9 32.6 140.2 140.0 35.6 169.2 145.2 230.0 177.9 56.3 122.6 105.5 99.7 10.0 55.8 29.5 35.8 423.5 165.8 49.8 52.1 52.7 54.2 49.0 51.0 53.4 51.1 52.9 53.0 51.9 57.7 18.6 6.4 10.3 5.2 50.6 14.1 26.5 62.1 10.8 9.4 22.4 30.4 50.0 24.3 36.0 14.7 8.4 67.1 33.4 31.8 31.3 69.3 108.2 19.1 31.8 23.4 25.2 86.7 2.2 50.4 108.7 26.4 16.3 31.7 15.2 61.9 25.0 141.9 89.8 15.2 3.2 56.2 48.8 18.8 31.4 281.6 13.1 23.8 55.2 1.9 25.2 56.5 29.9 2.0 7.3 57.9 13.6 18.8 100.2 35.9 10.8 89.0 30.3 11.8 6.6 14.0 28.7 96.8 118.9 26.2 15.2 29.7 59.7 38.1 36.6 31.9 CCDC189 "C16orf93, MGC104706" ENSG00000196118 "Coiled-coil domain containing 189" A1A4V9 16 30757423-30762221 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 18.4" "Group enriched" "Detected in many" 4 "Early spermatids: 208.2;Late spermatids: 318.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 12.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041806, HPA046289, HPA075094" Approved Approved Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA041806: AB_2677684, HPA046289: AB_2679615, HPA075094: " "unprognostic (5.84e-2)" "unprognostic (3.95e-3)" "unprognostic (1.86e-2)" "unprognostic (1.45e-4)" "unprognostic (3.60e-2)" "unprognostic (5.41e-3)" "unprognostic (7.76e-5)" "unprognostic (1.66e-2)" "unprognostic (1.82e-2)" "unprognostic (5.11e-3)" "unprognostic (2.15e-4)" "unprognostic (1.22e-3)" "unprognostic (1.06e-7)" "unprognostic (1.75e-3)" "unprognostic (2.14e-1)" "unprognostic (6.63e-2)" "unprognostic (3.41e-2)" 1.1 5.2 6.7 1.6 6.8 7.9 2.7 5.8 8.7 3.0 12.2 1.9 1.1 1.8 4.3 1.7 10.4 1.6 0.7 7.4 6.7 6.5 1.3 3.9 1.1 6.9 8.1 2.1 3.7 2.3 12.6 0.6 8.9 4.1 1.7 3.5 3.3 1.9 0.3 1.2 1.8 0.7 6.8 2.1 2.0 18.4 6.7 1.7 6.5 0.1 2.1 1.4 1.2 5.9 7.1 5.2 1.1 5.3 1.5 1.7 0.3 2.6 1.2 2.8 2.1 0.3 5.0 0.2 4.3 2.1 1.4 8.2 0.8 4.3 1.2 0.7 9.8 1.9 10.1 2.5 0.3 2.4 1.8 0.4 0.4 5.1 4.4 4.0 2.2 1.8 2.6 1.2 2.2 4.3 2.9 4.6 1.9 2.2 2.5 2.8 1.6 5.2 6.2 0.0 4.2 1.5 3.0 7.7 1.6 1.3 7.5 3.6 1.8 1.3 1.0 2.2 2.6 3.6 2.2 2.1 8.3 7.3 0.4 1.9 1.1 6.0 0.1 1.3 0.9 1.0 0.0 0.2 1.8 0.1 0.0 0.2 0.4 1.9 3.3 12.2 0.1 0.8 6.7 6.8 5.8 8.7 7.4 6.7 6.9 8.1 8.9 6.8 6.7 5.9 0.6 0.0 3.1 0.0 4.3 0.0 4.0 0.0 4.6 1.0 6.8 4.2 0.0 0.0 3.7 7.3 4.2 2.9 16.1 1.6 5.9 3.9 208.2 42.9 2.3 1.4 2.4 14.3 0.0 3.0 1.1 3.5 12.8 4.0 1.3 2.3 0.7 1.1 4.5 0.0 0.0 2.0 0.0 2.2 0.0 318.0 7.5 5.4 0.0 0.0 4.8 3.7 1.0 0.0 0.0 1.9 1.6 4.9 11.9 3.6 1.0 8.6 49.6 15.0 0.0 1.0 1.5 52.7 15.7 2.0 0.0 2.5 2.1 7.0 1.8 3.7 CCDC43 FLJ31795 ENSG00000180329 "Coiled-coil domain containing 43" Q96MW1 17 44673069-44689779 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 73.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023078, HPA023391" Enhanced Enhanced Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA023078: , HPA023391: AB_1846146" "unprognostic (6.05e-2)" "unprognostic (8.91e-2)" "unprognostic (8.75e-3)" "unprognostic (3.58e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (3.42e-5)" "prognostic unfavorable (1.33e-4)" "unprognostic (1.89e-1)" "unprognostic (1.14e-2)" "unprognostic (7.13e-2)" "prognostic unfavorable (3.19e-4)" "unprognostic (2.08e-1)" "unprognostic (1.63e-2)" "unprognostic (1.13e-1)" "unprognostic (1.76e-1)" "unprognostic (6.16e-2)" "unprognostic (1.11e-1)" 9.6 10.2 9.5 11.4 10.3 20.8 12.5 11.5 14.3 9.3 8.1 12.1 11.7 10.0 10.9 12.0 9.3 7.5 20.4 10.6 10.3 14.2 9.5 9.7 13.5 9.5 9.0 8.1 9.6 15.4 4.8 14.0 10.2 12.0 14.9 18.5 8.9 8.9 73.5 11.3 9.7 10.8 9.8 9.8 11.2 9.5 10.4 13.8 13.5 42.7 14.6 11.8 8.1 11.5 24.9 29.3 27.2 24.1 18.2 26.7 49.8 37.1 21.8 35.7 34.9 39.7 26.0 43.1 28.0 30.4 25.5 19.2 45.3 42.9 51.5 53.1 52.5 38.8 48.8 59.0 32.5 54.8 28.0 24.1 42.7 37.2 50.2 24.4 35.1 34.8 41.6 29.3 36.6 31.0 53.7 38.8 28.2 23.5 37.1 34.5 68.2 37.6 36.7 16.0 27.3 26.9 27.2 21.6 39.5 40.7 55.2 36.6 30.6 43.9 32.5 26.6 50.0 29.5 40.1 49.4 32.1 31.4 32.2 11.6 15.7 11.0 11.9 18.4 11.0 9.1 11.3 13.7 17.5 11.3 11.0 12.0 3.2 16.4 12.5 12.4 15.1 10.2 9.5 10.3 11.5 14.3 10.6 10.3 9.5 9.0 10.2 9.8 10.4 11.5 24.4 12.8 21.0 6.8 19.1 13.3 10.8 20.0 13.1 24.4 15.2 15.7 41.1 17.2 21.5 9.2 10.4 41.1 13.4 10.7 39.2 21.6 0.9 23.4 27.1 23.9 18.0 15.4 10.5 24.5 46.7 17.1 13.7 24.0 32.4 19.9 20.0 15.5 30.6 21.9 8.2 17.1 8.2 18.8 16.0 3.5 14.0 19.2 21.4 1.0 24.6 19.6 9.2 6.6 6.5 21.0 12.4 12.8 26.9 12.9 15.0 36.8 19.8 25.4 6.6 23.4 17.5 3.6 12.4 24.8 11.2 25.3 16.7 22.6 22.6 8.7 CCDC50 "C3orf6, DFNA44, Ymer" ENSG00000152492 "Coiled-coil domain containing 50" Q8IVM0 3 191329085-191398659 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 363.7;Oligodendrocyte precursor cells: 365.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 630.7" "Lineage enriched" "Detected in all" 5 "dendritic cells: 630.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001336 Approved Supported Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "HPA001336: AB_1078421" "unprognostic (5.01e-2)" "unprognostic (1.44e-1)" "unprognostic (7.84e-2)" "unprognostic (8.77e-3)" "unprognostic (1.73e-2)" "unprognostic (8.29e-2)" "prognostic unfavorable (2.48e-5)" "unprognostic (3.03e-2)" "unprognostic (2.51e-2)" "unprognostic (4.48e-2)" "unprognostic (3.17e-3)" "unprognostic (2.05e-2)" "unprognostic (7.79e-2)" "unprognostic (1.01e-1)" "unprognostic (6.19e-2)" "unprognostic (7.57e-2)" "unprognostic (4.19e-1)" 63.2 28.3 19.6 34.3 20.7 10.3 30.6 21.5 19.1 24.1 18.8 26.9 24.2 33.0 24.8 27.9 24.3 34.8 39.7 17.6 23.3 32.4 56.5 31.6 42.2 24.1 22.0 46.2 35.1 27.6 13.5 34.9 24.1 26.2 25.4 11.8 23.7 33.3 19.0 18.4 25.8 48.1 23.2 45.0 24.3 29.6 21.3 17.7 27.4 26.1 41.0 36.7 18.6 24.7 74.9 24.5 93.6 24.7 82.3 72.1 32.3 135.4 135.2 95.4 95.0 52.6 28.9 14.6 163.0 76.8 70.6 83.6 75.6 60.5 141.9 109.0 37.8 10.0 31.7 60.3 120.8 36.8 37.8 58.2 79.3 75.6 169.7 82.2 148.7 0.0 33.9 77.3 85.4 26.0 0.2 23.1 33.2 7.6 103.0 56.3 51.9 73.1 104.3 31.9 21.8 33.2 48.2 51.6 95.8 67.3 35.6 32.9 153.3 93.4 78.4 68.4 176.3 118.6 54.9 0.9 50.5 0.1 76.9 0.1 22.1 2.1 5.9 20.8 2.4 128.5 6.1 3.9 44.3 76.5 1.3 1.5 2.2 24.0 12.1 630.7 22.1 18.0 19.6 20.7 21.5 19.1 17.6 23.3 24.1 22.0 24.1 23.2 21.3 24.7 143.5 25.6 54.5 40.5 134.5 46.9 52.5 30.7 30.7 27.2 32.5 37.5 48.4 58.6 34.7 51.5 27.1 28.1 363.7 44.1 31.3 120.4 183.0 97.3 58.1 134.0 22.8 11.2 15.8 78.5 36.3 66.6 41.8 79.0 2.5 58.5 175.6 79.5 84.4 25.2 41.3 33.8 38.7 59.4 78.3 92.1 69.3 61.4 53.4 98.4 101.4 32.1 5.2 365.4 28.9 174.7 33.9 75.6 102.7 69.8 37.6 71.8 26.3 14.4 59.2 74.1 65.7 73.2 26.6 24.0 32.5 33.5 22.4 49.5 33.7 62.4 CCDC6 "D10S170, H4, PTC, TPC, TST1" ENSG00000108091 "Coiled-coil domain containing 6" Q16204 10 59788747-59906556 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019049, HPA019051" Enhanced Supported Cytosol No No 12000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 41: Macrophages - Immune response" Cytosol "HPA019049: AB_1846163, HPA019051: AB_1846164" "unprognostic (1.88e-2)" "unprognostic (1.72e-2)" "unprognostic (4.41e-2)" "unprognostic (1.25e-3)" "unprognostic (5.98e-3)" "prognostic favorable (5.48e-4)" "prognostic unfavorable (1.11e-4)" "unprognostic (7.39e-2)" "unprognostic (2.45e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.95e-4)" "unprognostic (4.08e-1)" "unprognostic (4.69e-2)" "unprognostic (2.23e-1)" "unprognostic (2.56e-1)" "unprognostic (9.95e-2)" "unprognostic (4.19e-2)" 11.9 12.2 21.1 13.9 23.4 16.8 22.4 10.2 20.0 23.4 8.5 23.5 22.8 24.9 16.7 34.1 25.3 16.7 10.0 24.9 21.4 21.2 12.1 17.3 21.4 12.4 15.8 15.7 25.2 17.9 11.5 13.2 17.4 19.4 19.8 18.3 29.0 14.3 17.3 28.6 16.2 30.8 11.9 14.7 18.6 11.4 20.8 12.1 18.3 12.2 21.6 17.3 23.1 12.6 42.9 38.0 18.7 41.9 27.8 41.6 37.9 20.6 27.2 20.2 23.7 74.4 81.8 36.5 30.2 34.6 11.7 61.7 37.7 37.5 30.0 55.1 18.7 29.8 29.1 45.5 33.5 34.5 26.9 30.3 48.7 33.7 81.8 28.3 30.2 20.4 22.6 22.7 26.6 57.6 14.5 19.8 29.9 40.1 25.6 19.2 30.5 23.0 33.9 36.2 19.0 16.6 26.1 107.8 23.1 24.1 68.7 18.4 31.1 18.8 33.9 29.3 34.9 12.0 14.9 16.3 29.6 64.6 11.9 0.0 2.0 0.0 1.0 2.3 1.1 4.3 1.5 1.3 5.0 4.9 1.3 1.0 0.1 0.8 1.3 1.3 1.4 1.0 21.1 23.4 10.2 20.0 24.9 21.4 12.4 15.8 17.4 11.9 20.8 12.6 24.0 99.3 25.9 45.1 41.6 95.0 51.7 25.3 70.0 15.1 51.2 38.7 16.5 28.6 46.3 25.8 41.7 37.8 31.4 42.6 29.4 50.2 27.6 105.2 54.6 22.4 27.0 25.7 83.2 65.3 18.8 27.8 39.8 134.5 29.1 45.2 17.2 20.1 23.1 16.8 58.4 38.9 30.5 40.7 35.3 80.6 24.5 36.4 16.0 32.8 23.0 11.5 13.4 55.3 34.2 50.2 25.0 19.5 26.4 52.2 47.1 48.4 28.1 49.8 19.7 31.4 27.0 2.3 22.4 92.3 80.1 27.0 24.3 32.5 46.3 46.1 CCDC9 DKFZP586M1019 ENSG00000105321 "Coiled-coil domain containing 9" Q9Y3X0 19 47255980-47273701 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 50.6;Late spermatids: 79.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "NB-4: 116.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045624, HPA072007" Enhanced Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 24: NB-4 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA045624: AB_10961402, HPA072007: AB_2686482" "unprognostic (4.53e-3)" "unprognostic (1.75e-1)" "unprognostic (3.70e-3)" "unprognostic (8.22e-2)" "unprognostic (7.47e-2)" "unprognostic (1.15e-2)" "unprognostic (8.35e-3)" "unprognostic (1.45e-1)" "unprognostic (4.99e-1)" "unprognostic (1.57e-2)" "unprognostic (2.40e-1)" "unprognostic (9.78e-2)" "unprognostic (2.58e-1)" "unprognostic (2.45e-2)" "unprognostic (1.02e-1)" "unprognostic (7.46e-3)" "unprognostic (4.02e-1)" 22.7 21.1 11.7 16.1 12.2 40.7 22.2 10.5 16.1 27.8 17.3 24.8 13.7 24.7 8.8 18.1 24.8 10.3 21.8 12.7 10.0 25.9 22.7 26.6 10.6 15.9 12.0 30.7 49.0 14.0 16.6 13.6 11.3 25.8 8.5 12.6 20.0 12.3 26.2 34.9 18.9 9.8 9.5 23.1 24.8 35.8 12.6 9.3 23.0 11.7 7.7 23.8 23.9 12.3 27.5 27.7 21.2 23.7 6.6 17.9 24.1 37.2 16.4 22.4 24.5 29.5 21.1 12.5 10.0 24.8 18.6 25.5 19.7 16.0 12.1 33.3 12.3 32.3 27.3 22.7 21.1 13.2 31.9 19.2 23.0 21.4 20.0 19.0 15.1 15.6 45.0 61.8 15.0 32.8 15.4 116.9 23.7 45.3 10.8 26.9 20.2 14.4 10.2 19.7 8.3 21.1 50.5 36.4 20.3 17.3 30.2 26.7 20.9 25.8 23.0 15.6 32.2 20.5 38.5 19.0 24.2 17.8 20.3 0.4 1.1 2.0 1.3 1.4 0.7 0.6 1.0 1.0 0.9 0.9 1.0 0.7 3.6 1.1 0.8 1.4 1.9 0.4 11.7 12.2 10.5 16.1 12.7 10.0 15.9 12.0 11.3 9.5 12.6 12.3 13.6 6.4 1.7 1.3 16.4 14.0 15.7 1.8 12.0 3.1 8.9 5.2 3.0 2.8 1.9 1.8 4.2 5.4 9.3 13.1 5.9 7.5 50.6 13.0 10.3 9.7 3.6 8.2 1.4 11.2 9.1 7.6 14.3 16.8 8.2 4.3 3.3 3.6 5.8 0.0 1.0 12.0 2.0 7.8 14.4 79.3 4.4 9.8 7.2 1.9 10.4 1.8 7.2 0.5 0.9 11.1 11.5 3.8 15.2 8.9 7.8 6.7 2.1 7.6 6.6 8.7 10.5 2.8 7.5 12.7 17.8 15.3 12.2 5.3 8.4 13.5 CCHCR1 "C6orf18, HCR" ENSG00000204536 "Coiled-coil alpha-helical rod protein 1" Q8TD31 6 31142439-31158238 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "testis: 138.9" "Cell type enhanced" "Detected in many" "Early spermatids: 89.7;Endometrial ciliated cells: 68.0;Glandular and luminal cells: 161.9;Late spermatids: 160.7;Spermatocytes: 68.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 38.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA054167 Supported Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 44: Endometrium - Transcription" Cytosol "HPA054167: AB_2682403" "unprognostic (6.68e-2)" "unprognostic (7.98e-2)" "unprognostic (1.24e-1)" "unprognostic (1.23e-1)" "unprognostic (1.88e-1)" "unprognostic (3.11e-3)" "unprognostic (2.23e-3)" "unprognostic (1.99e-1)" "unprognostic (2.74e-1)" "unprognostic (5.36e-3)" "unprognostic (1.65e-1)" "unprognostic (2.07e-1)" "unprognostic (3.85e-3)" "unprognostic (1.06e-1)" "unprognostic (4.35e-2)" "unprognostic (3.57e-1)" "unprognostic (4.17e-2)" 10.4 7.6 1.4 2.8 1.4 1.3 11.8 1.6 2.3 18.1 1.5 16.2 10.1 12.4 5.7 15.1 18.7 1.7 11.7 1.5 1.6 19.7 12.2 9.0 6.9 1.6 1.4 19.0 14.5 1.3 9.3 0.9 1.9 19.9 3.3 1.2 11.4 4.0 19.3 17.4 14.7 1.6 1.0 13.3 13.9 138.9 2.2 2.1 16.1 1.1 1.7 13.4 15.4 1.5 38.9 3.0 9.8 1.6 6.1 7.4 8.8 3.3 1.1 0.5 1.2 14.9 0.7 5.1 17.6 8.5 23.1 1.6 0.6 15.4 1.5 5.8 23.9 18.1 13.2 11.7 3.7 0.4 11.5 9.7 1.8 6.9 1.5 7.2 8.1 27.2 7.3 10.3 4.1 2.8 6.7 19.9 0.6 1.4 0.2 12.0 13.8 9.6 9.6 3.8 29.2 4.9 11.7 0.0 2.8 6.0 4.2 9.3 1.0 14.5 4.8 0.3 9.4 23.7 14.7 20.7 3.1 4.4 1.5 0.2 0.6 0.5 0.9 0.3 0.8 0.3 0.8 1.4 0.5 0.6 1.3 1.3 0.0 1.0 0.4 1.2 1.5 0.6 1.4 1.4 1.6 2.3 1.5 1.6 1.6 1.4 1.9 1.0 2.2 1.5 8.0 3.2 5.1 10.4 7.7 9.7 13.0 12.8 8.6 9.6 8.2 10.9 8.7 11.5 11.0 3.7 0.0 3.1 5.4 41.9 11.7 8.9 89.7 68.0 19.0 6.7 29.3 6.3 5.2 10.5 7.5 7.7 28.5 161.9 0.0 15.0 5.7 7.5 6.8 15.2 4.3 27.6 0.0 5.0 3.7 160.7 9.9 5.4 7.2 1.9 8.4 5.1 9.2 0.5 1.8 8.4 17.3 11.7 6.7 9.0 36.2 7.6 15.9 2.3 6.6 9.2 8.6 68.6 21.1 7.3 5.8 1.4 6.0 14.7 35.9 8.3 CCN4 "WISP-1, WISP1, WISP1-OT1, WISP1-UT1" ENSG00000104415 "Cellular communication network factor 4" O95388 8 133191039-133231690 "Cancer-related genes, Predicted secreted proteins" "Cell adhesion, Wnt signaling pathway" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in single" "Cardiomyocytes: 1.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HSkMC: 110.5;hTEC/SVTERT24-B: 64.5;U-2197: 61.9" "Region enriched" "Detected in some" 6 "olfactory bulb: 9.8" "Low region specificity" "Detected in many" "HPA007121, CAB012205" Uncertain Approved Cytosol "Secreted to extracellular matrix" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "CAB012205: , HPA007121: AB_1858844" "unprognostic (7.77e-2)" "unprognostic (2.05e-1)" "unprognostic (3.30e-2)" "unprognostic (3.20e-1)" "unprognostic (7.72e-2)" "unprognostic (6.63e-2)" "unprognostic (8.61e-3)" "unprognostic (3.26e-2)" "unprognostic (2.07e-3)" "unprognostic (1.41e-3)" "unprognostic (3.01e-2)" "unprognostic (2.67e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (7.52e-3)" "unprognostic (2.55e-3)" "unprognostic (6.03e-2)" "unprognostic (5.67e-3)" 4.4 10.3 1.3 7.6 2.6 0.0 0.9 0.5 1.4 10.9 0.9 3.9 1.2 14.0 0.9 0.9 5.9 7.8 3.7 1.3 0.4 15.8 2.0 8.3 3.0 0.7 0.6 6.0 0.8 9.2 2.3 2.8 0.7 3.3 0.8 0.0 1.1 1.4 0.4 1.4 2.3 13.6 0.6 2.2 2.8 1.2 0.9 0.2 1.1 0.2 3.9 6.0 3.6 0.8 0.0 0.5 0.0 0.0 7.6 4.2 0.1 0.1 8.4 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.6 0.0 0.0 110.5 0.0 64.5 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.6 0.0 0.0 0.0 14.8 0.8 61.9 0.0 0.0 0.0 0.0 12.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.6 0.5 1.4 1.3 0.4 0.7 0.6 0.7 0.6 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 CCNB1 CCNB ENSG00000134057 "Cyclin B1" P14635 5 69167135-69178245 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 52.9;lymphoid tissue: 76.2" "Cell type enriched" "Detected in many" 6 "Extravillous trophoblasts: 723.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 3.0;white matter: 8.3" "Not detected" "Not detected" "CAB000115, CAB003804, HPA030741, HPA061448" Enhanced Enhanced Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "CAB000115: , CAB003804: AB_562272, HPA030741: AB_2673586, HPA061448: AB_2684522" "unprognostic (4.12e-2)" "unprognostic (2.75e-2)" "unprognostic (1.91e-3)" "unprognostic (4.08e-3)" "unprognostic (2.78e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.54e-7)" "prognostic unfavorable (3.38e-4)" "unprognostic (1.43e-2)" "unprognostic (1.63e-2)" "unprognostic (2.49e-3)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.11e-16)" "unprognostic (2.44e-1)" "unprognostic (3.73e-1)" "unprognostic (1.44e-1)" "unprognostic (5.15e-3)" 4.0 5.1 4.0 26.0 3.9 52.9 10.0 6.0 4.9 6.3 2.8 22.2 20.9 7.7 5.4 36.0 8.2 4.0 3.0 3.8 4.0 4.8 4.3 3.9 54.5 6.2 4.4 5.0 4.2 5.8 2.6 20.8 6.5 3.8 29.5 5.7 6.5 3.9 3.4 14.5 19.5 14.4 3.5 11.1 10.8 32.9 5.2 76.2 9.3 2.0 67.0 8.4 10.4 4.0 466.0 317.1 423.5 377.1 22.2 37.1 980.2 201.3 150.8 521.3 437.0 471.2 423.9 285.2 239.1 187.6 594.2 284.2 432.4 442.8 577.2 281.4 217.2 181.6 243.2 323.2 6.8 160.5 197.7 16.6 27.7 300.5 207.2 47.7 282.8 274.2 223.5 217.9 430.2 441.4 220.5 184.7 236.7 153.3 199.3 228.4 305.2 288.2 192.6 168.2 212.7 133.5 347.7 160.3 141.9 236.4 306.4 162.5 119.8 114.4 368.5 207.6 510.2 109.2 216.6 399.8 158.8 271.9 358.6 3.1 2.0 1.5 3.2 5.1 4.5 15.4 8.3 7.4 6.0 11.1 2.7 2.6 1.3 8.2 2.4 5.0 17.6 6.2 4.0 3.9 6.0 4.9 3.8 4.0 6.2 4.4 6.5 3.5 5.2 4.0 4.0 0.0 0.5 2.0 11.8 11.5 7.2 32.1 4.6 4.8 9.8 12.3 1.9 1.5 8.8 5.5 2.1 108.2 8.3 9.5 1.9 6.5 110.2 15.2 7.4 6.6 1.2 76.2 2.7 1.4 723.1 18.3 21.4 13.0 2.5 63.0 8.9 3.2 60.2 0.0 2.1 13.8 73.2 12.0 7.2 17.8 3.1 9.7 3.6 1.0 2.7 3.9 2.1 0.5 1.0 2.4 1.5 2.6 24.1 4.5 2.5 5.6 13.1 4.1 6.6 4.9 18.5 74.3 62.2 37.4 7.2 41.5 8.0 11.8 33.4 7.8 CCT2 Cctb ENSG00000166226 "Chaperonin containing TCP1 subunit 2" P78371 12 69585426-69601570 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1471.3;Spermatocytes: 625.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003197, HPA003198" Enhanced Supported Cytosol NA NA 3500000 "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "HPA003197: AB_1078425, HPA003198: AB_1078424" "unprognostic (1.79e-3)" "unprognostic (2.35e-1)" "unprognostic (1.40e-3)" "unprognostic (1.53e-1)" "unprognostic (4.42e-2)" "prognostic unfavorable (8.38e-4)" "prognostic unfavorable (3.61e-9)" "unprognostic (5.28e-3)" "unprognostic (2.15e-2)" "unprognostic (1.08e-2)" "unprognostic (5.34e-2)" "prognostic unfavorable (3.67e-4)" "unprognostic (6.53e-3)" "unprognostic (1.59e-1)" "unprognostic (1.12e-1)" "unprognostic (1.63e-1)" "unprognostic (7.21e-2)" 64.0 69.9 56.8 77.7 61.3 140.5 85.5 62.4 70.6 51.9 68.4 70.6 53.2 66.9 43.7 69.4 69.5 54.7 68.6 60.6 64.4 92.9 72.2 46.6 94.9 62.4 59.5 65.2 53.3 71.6 37.8 70.2 62.5 57.9 85.9 57.5 45.4 52.5 103.9 55.9 51.5 83.3 62.2 51.5 52.0 216.0 59.8 100.7 56.1 73.2 108.8 106.6 49.6 63.8 266.1 388.1 343.8 330.7 154.2 174.5 392.3 280.4 203.8 448.0 276.1 529.7 121.7 572.6 266.2 222.9 281.8 250.2 538.2 313.0 536.6 319.1 398.6 418.7 313.5 331.8 171.8 520.1 255.5 152.7 195.3 425.9 248.1 308.7 296.4 311.4 519.2 165.0 410.2 378.9 496.0 446.7 482.4 273.2 403.7 389.3 375.9 373.1 369.4 476.9 334.1 281.3 291.0 314.2 289.2 284.3 411.4 371.6 196.0 231.4 292.2 275.0 427.3 203.5 409.6 614.6 201.9 354.8 290.8 36.6 41.0 12.5 47.3 66.0 72.7 74.2 54.0 61.5 72.9 60.7 62.2 68.5 3.7 65.3 62.1 66.9 63.7 70.0 56.8 61.3 62.4 70.6 60.6 64.4 62.4 59.5 62.5 62.2 59.8 63.8 80.4 35.3 47.4 17.3 97.2 136.6 233.9 173.8 126.3 51.1 70.1 89.7 81.5 57.2 110.8 80.9 79.2 189.1 93.3 48.1 92.0 198.8 1471.3 150.9 126.5 95.3 106.2 226.4 21.5 128.4 209.1 102.1 60.6 107.1 105.4 112.3 52.5 46.2 127.1 42.1 31.3 94.4 109.9 44.3 74.9 430.3 76.7 70.5 46.2 11.2 87.7 67.9 57.7 21.6 20.6 150.7 50.8 66.5 100.7 165.8 34.4 127.4 127.5 56.6 85.5 128.4 178.3 625.4 391.5 112.1 117.3 153.4 93.9 154.1 154.8 161.9 CCT6A "CCT6, Cctz, HTR3, TCP20, TCPZ, TTCP20" ENSG00000146731 "Chaperonin containing TCP1 subunit 6A" P40227 7 56051685-56063989 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A-431: 1612.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042996, HPA045576, HPA049949" Supported Approved Cytosol NA NA 3600000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA042996: AB_2678261, HPA045576: AB_2679372, HPA049949: AB_2680968" "prognostic unfavorable (4.04e-4)" "unprognostic (5.32e-3)" "unprognostic (1.34e-1)" "unprognostic (2.81e-1)" "unprognostic (3.02e-1)" "prognostic unfavorable (8.45e-4)" "prognostic unfavorable (9.00e-10)" "unprognostic (1.19e-2)" "unprognostic (3.17e-1)" "unprognostic (1.67e-2)" "unprognostic (3.24e-2)" "unprognostic (4.82e-2)" "prognostic unfavorable (2.19e-4)" "unprognostic (1.35e-1)" "unprognostic (1.20e-1)" "unprognostic (1.78e-1)" "unprognostic (9.44e-3)" 58.5 58.8 48.3 66.6 50.5 67.0 59.7 52.6 71.1 43.5 55.9 52.6 53.2 52.0 38.2 68.1 50.9 39.8 56.7 50.2 56.4 72.5 53.3 41.1 69.6 52.5 52.9 42.1 60.8 69.4 39.1 56.4 53.9 44.9 60.1 46.5 45.5 49.4 124.3 58.0 51.8 61.4 53.2 46.1 52.2 49.5 53.5 61.3 49.7 85.5 81.1 72.1 47.6 55.3 1612.6 357.8 211.6 322.5 145.7 181.6 243.2 293.0 165.4 284.4 227.7 407.0 196.7 487.8 222.9 192.1 511.6 333.2 438.2 339.2 390.0 276.8 328.1 306.1 337.0 363.8 157.3 444.1 240.5 157.1 191.1 287.8 284.4 224.8 283.7 221.2 682.0 121.2 325.5 199.2 346.4 392.7 449.3 356.6 466.8 315.1 213.9 284.8 321.6 302.3 280.3 282.0 259.2 440.7 272.6 321.8 324.6 341.6 238.6 194.1 372.4 651.4 617.1 146.7 321.5 596.7 194.4 389.0 658.4 21.0 69.9 34.0 57.8 87.7 77.3 65.9 59.7 63.3 96.5 50.4 59.8 64.8 8.4 77.7 103.0 54.0 68.3 81.2 48.3 50.5 52.6 71.1 50.2 56.4 52.5 52.9 53.9 53.2 53.5 55.3 94.6 89.8 106.4 13.1 83.3 108.8 201.4 175.3 91.6 60.2 77.4 83.2 114.0 65.8 187.7 47.8 27.1 199.6 93.4 56.6 88.0 263.1 22.5 209.6 121.0 129.4 102.1 163.4 19.3 274.2 264.8 97.0 88.2 133.8 131.7 123.4 71.0 66.7 148.2 38.7 23.7 94.2 124.1 83.5 79.2 19.5 70.5 104.0 58.7 19.7 206.9 80.7 80.3 18.1 22.7 245.6 66.7 90.7 106.4 184.8 65.2 146.4 190.3 60.8 59.2 99.1 136.3 115.0 219.8 160.9 109.7 199.9 91.8 189.7 138.6 145.9 CCT6B "Cctz2, TSA303" ENSG00000132141 "Chaperonin containing TCP1 subunit 6B" Q92526 17 34927859-34981078 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "testis: 126.1" "Group enriched" "Detected in many" 27 "Early spermatids: 448.5;Late spermatids: 185.2;Spermatocytes: 490.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPMI-8226: 12.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042996, HPA045576, HPA049949" Uncertain Approved Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 25: RPMI-8226 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA042996: AB_2678261, HPA045576: AB_2679372, HPA049949: AB_2680968" "unprognostic (1.56e-1)" "unprognostic (1.72e-2)" "unprognostic (2.99e-3)" "unprognostic (6.11e-2)" "unprognostic (3.38e-1)" "unprognostic (1.15e-1)" "unprognostic (1.12e-3)" "unprognostic (3.61e-2)" "unprognostic (1.75e-1)" "unprognostic (1.44e-3)" "unprognostic (9.56e-3)" "unprognostic (3.61e-2)" "unprognostic (4.82e-7)" "unprognostic (1.24e-1)" "unprognostic (4.30e-1)" "unprognostic (4.23e-4)" "unprognostic (1.49e-1)" 2.9 3.3 1.9 0.8 2.3 3.8 5.5 2.0 2.7 2.2 1.6 1.7 1.4 1.9 5.5 1.8 2.7 0.9 1.7 1.7 2.0 4.0 5.0 1.2 1.4 2.2 2.1 2.4 2.6 2.5 2.7 0.6 2.3 2.7 1.1 2.3 3.3 2.6 5.1 2.7 1.4 1.6 2.3 1.6 2.0 126.1 2.0 1.6 2.9 3.8 1.7 1.9 1.5 2.7 0.7 1.0 2.6 1.1 3.3 2.0 0.9 1.3 5.3 2.2 3.1 0.7 2.1 5.0 0.5 2.4 1.6 1.0 0.1 0.7 0.7 0.5 1.9 0.7 0.3 0.6 4.5 2.4 0.7 2.7 1.3 0.2 2.6 0.4 0.6 0.8 0.5 5.0 2.4 1.9 0.5 5.2 1.4 0.4 0.6 2.4 1.2 12.2 1.4 0.8 3.0 1.5 2.4 0.9 4.1 0.6 1.9 2.4 0.5 1.0 0.1 1.2 0.6 4.4 1.0 4.7 1.1 1.5 1.3 0.0 1.1 0.9 0.6 1.1 0.6 0.9 0.7 0.4 2.6 0.8 1.0 1.0 0.0 1.6 1.1 0.6 0.3 0.6 1.9 2.3 2.0 2.7 1.7 2.0 2.2 2.1 2.3 2.3 2.0 2.7 2.4 0.0 3.1 4.6 2.6 2.4 2.8 3.2 6.2 1.5 8.7 7.0 4.2 4.3 3.9 1.8 0.0 1.8 4.0 0.9 3.9 3.4 448.5 8.8 3.7 2.1 0.0 0.8 3.9 8.0 0.5 3.5 1.5 3.6 2.5 4.6 0.7 3.1 1.5 0.0 3.7 2.3 6.1 2.2 4.0 185.2 10.8 2.9 5.4 4.7 1.6 8.7 4.1 7.1 10.7 2.7 1.6 4.1 3.9 2.1 0.7 6.9 8.8 2.5 0.0 3.7 3.0 490.2 13.5 3.1 2.6 0.8 2.7 6.9 1.8 3.6 CCT7 "Ccth, Nip7-1" ENSG00000135624 "Chaperonin containing TCP1 subunit 7" Q99832 2 73233420-73253021 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 393.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008425 Approved Approved Cytosol NA NA 1900000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA008425: AB_1078428" "unprognostic (5.02e-3)" "unprognostic (9.51e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.69e-4)" "unprognostic (4.60e-2)" "unprognostic (1.37e-2)" "prognostic unfavorable (1.84e-5)" "unprognostic (4.37e-3)" "unprognostic (8.76e-2)" "unprognostic (3.17e-1)" "unprognostic (4.24e-2)" "unprognostic (3.78e-1)" "unprognostic (1.41e-2)" "unprognostic (3.60e-2)" "unprognostic (1.07e-1)" "unprognostic (3.07e-3)" "unprognostic (3.12e-2)" 113.3 150.8 104.5 108.6 109.7 93.4 111.4 114.6 110.9 109.6 118.1 113.6 84.8 123.0 117.1 119.7 133.3 69.0 162.9 109.1 114.5 111.9 114.0 83.4 126.5 109.7 109.4 140.4 114.2 134.7 97.0 101.4 114.0 115.2 123.2 83.7 92.1 110.7 252.4 103.9 88.3 147.5 112.7 98.7 106.8 162.9 110.7 153.0 87.4 241.2 158.5 120.0 101.1 120.7 396.3 641.9 361.8 393.0 259.1 211.7 460.7 348.6 311.8 573.6 359.0 1054.5 272.1 760.3 219.0 365.9 529.3 328.2 816.6 533.8 635.9 420.7 722.9 516.2 403.2 755.3 287.5 614.9 367.5 328.9 297.7 565.9 683.3 301.4 521.0 444.7 650.2 265.8 488.7 613.6 686.5 776.1 519.1 540.6 455.8 614.8 927.2 535.0 411.6 374.7 512.4 315.9 302.6 411.0 406.7 333.6 235.2 331.4 339.7 390.9 464.3 245.7 679.7 298.1 341.1 709.2 319.4 686.1 435.6 157.7 131.4 78.1 190.8 178.8 211.3 216.6 193.5 191.4 202.0 208.8 208.9 195.3 39.5 192.1 209.8 203.7 186.0 299.3 104.5 109.7 114.6 110.9 109.1 114.5 109.7 109.4 114.0 112.7 110.7 120.7 77.7 57.7 45.6 12.4 87.5 69.1 149.7 161.5 55.8 81.1 63.8 77.1 99.2 68.6 96.7 58.8 18.8 190.2 74.3 54.8 109.5 148.2 393.0 99.8 96.4 91.6 75.3 77.8 10.8 139.0 213.2 94.8 57.1 58.1 73.6 108.2 61.8 69.3 133.6 82.4 13.3 102.2 118.0 58.8 58.1 246.3 104.7 57.3 74.7 10.3 98.9 125.5 74.2 12.1 15.0 134.1 60.3 107.2 112.3 156.0 67.3 133.2 108.2 88.6 72.3 91.8 126.7 288.9 127.8 71.1 73.6 166.5 77.2 190.6 127.6 112.5 CD207 "CLEC4K, Langerin" ENSG00000116031 "CD207 molecule" Q9UJ71 2 70830211-70835816 "CD markers, Disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 87.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 4.0;Langerhans cells: 9.7;Macrophages: 7.6;Melanocytes: 5.4;Suprabasal keratinocytes: 5.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "myeloid DC: 1.1" "Lineage enriched" "Detected in single" 12 "dendritic cells: 1.1" "Cell line enriched" "Detected in some" 4 "AN3-CA: 8.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002222, HPA011216" Enhanced Uncertain Cytosol No NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" Cytosol "CAB002222: AB_563850, HPA011216: AB_1078453" "unprognostic (1.45e-2)" "unprognostic (8.28e-3)" "unprognostic (9.34e-2)" "unprognostic (1.65e-1)" "unprognostic (1.38e-1)" "unprognostic (2.23e-1)" "unprognostic (3.02e-1)" "unprognostic (1.27e-3)" "unprognostic (1.05e-1)" "unprognostic (4.86e-2)" "unprognostic (3.45e-1)" "unprognostic (1.63e-1)" "unprognostic (7.92e-4)" "unprognostic (2.13e-2)" "unprognostic (1.81e-1)" "unprognostic (1.98e-1)" "unprognostic (2.46e-2)" 0.4 0.1 0.0 0.3 0.0 0.0 3.2 0.0 0.0 1.6 0.1 1.2 3.7 0.8 0.4 17.8 0.9 2.0 0.2 0.0 0.0 0.1 0.7 1.6 0.9 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 2.4 2.7 5.5 1.1 0.8 0.8 87.7 4.9 0.7 0.0 3.7 1.4 0.5 0.0 3.4 0.1 0.3 4.8 1.4 1.7 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.1 1.6 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.6 4.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.2 0.0 7.6 5.4 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.1 0.0 0.0 0.0 CD320 "8D6, 8D6A" ENSG00000167775 "CD320 molecule" Q9NPF0 19 8302127-8308358 "CD markers, Disease related genes, Predicted membrane proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 419.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 418.4;RPMI-8226: 381.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014500, HPA073489" Approved Approved Cytosol NA NA 61000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA014500: AB_1846295, HPA073489: AB_2686609" "unprognostic (9.97e-2)" "unprognostic (2.62e-1)" "unprognostic (3.51e-1)" "unprognostic (2.54e-3)" "unprognostic (2.17e-1)" "unprognostic (2.39e-2)" "prognostic unfavorable (4.02e-4)" "unprognostic (4.19e-2)" "unprognostic (7.13e-2)" "unprognostic (1.31e-1)" "unprognostic (9.35e-3)" "unprognostic (1.25e-1)" "unprognostic (2.03e-1)" "unprognostic (1.07e-1)" "unprognostic (8.92e-2)" "unprognostic (3.14e-1)" "unprognostic (9.90e-2)" 61.8 44.7 39.3 15.8 36.7 8.1 57.5 41.1 42.8 26.2 46.7 52.9 18.8 34.2 63.4 15.7 28.4 16.5 48.4 34.1 40.0 31.2 24.1 25.9 15.3 42.8 40.9 27.7 45.3 15.5 25.7 11.4 46.7 35.2 15.5 4.7 21.3 12.8 34.2 15.8 43.8 13.0 40.9 57.1 45.5 38.3 44.1 10.5 44.4 16.7 7.1 32.5 21.3 36.0 71.7 71.5 15.5 201.1 49.2 25.6 36.6 36.6 48.5 71.2 54.3 77.0 41.7 63.7 111.4 26.8 53.3 44.7 0.1 57.7 13.8 90.0 216.7 30.8 58.4 111.5 33.1 58.8 74.6 24.4 13.6 41.7 34.4 31.7 70.3 42.3 95.4 214.4 28.4 67.6 63.1 418.4 109.3 62.1 293.6 76.6 21.5 381.7 53.9 1.7 143.4 62.3 75.5 32.1 94.5 11.5 2.6 26.2 40.5 82.0 60.6 122.9 117.0 200.5 136.3 71.0 58.4 214.3 90.2 0.5 2.7 0.1 219.9 3.0 125.9 48.4 140.0 117.7 5.1 49.4 94.1 107.1 3.3 91.0 2.2 113.8 102.4 69.4 39.3 36.7 41.1 42.8 34.1 40.0 42.8 40.9 46.7 40.9 44.1 36.0 419.5 12.8 18.8 6.2 34.4 18.5 29.8 39.3 25.6 53.7 42.6 47.6 34.6 14.3 13.0 18.4 33.3 42.7 53.4 126.2 13.7 46.5 25.2 14.6 28.2 146.8 50.9 22.5 6.1 18.5 54.0 53.3 23.0 22.5 11.4 65.6 143.5 20.0 29.5 21.9 10.2 69.6 26.4 7.5 20.2 57.9 21.8 6.4 39.2 34.7 6.2 21.6 33.0 9.0 5.5 18.6 54.7 17.0 121.2 60.8 3.3 48.0 8.8 46.2 13.1 32.0 26.3 122.1 30.2 10.4 14.1 35.4 43.3 119.3 128.6 21.1 CDC37 P50CDC37 ENSG00000105401 "Cell division cycle 37, HSP90 cochaperone" Q16543 19 10391133-10420121 "Cancer-related genes, Predicted intracellular proteins, Transporters" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003928, CAB004214" Supported Supported Cytosol NA NA 610000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 24: NB-4 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB004214: AB_627232, HPA003928: AB_1846373" "unprognostic (2.40e-1)" "unprognostic (1.06e-1)" "unprognostic (1.27e-1)" "unprognostic (2.33e-2)" "unprognostic (2.46e-3)" "unprognostic (6.21e-2)" "unprognostic (1.37e-1)" "unprognostic (7.90e-2)" "unprognostic (1.25e-1)" "unprognostic (7.61e-3)" "unprognostic (1.96e-2)" "unprognostic (1.82e-2)" "unprognostic (1.84e-2)" "prognostic favorable (2.33e-4)" "unprognostic (5.80e-2)" "unprognostic (1.23e-1)" "unprognostic (3.02e-2)" 149.9 93.6 82.2 81.3 84.6 89.5 130.6 75.0 104.2 111.4 72.1 109.9 58.1 110.0 34.2 125.7 98.5 39.8 186.0 86.3 85.8 123.2 102.2 129.9 66.5 85.9 85.8 105.9 100.3 59.3 74.6 62.7 88.1 105.0 48.2 34.6 96.6 52.2 313.2 100.9 96.3 50.2 75.7 137.5 102.8 77.5 82.5 69.3 100.8 222.6 52.4 110.3 103.0 87.8 279.2 181.2 95.5 137.5 128.8 111.8 122.9 322.8 144.6 198.3 168.8 209.1 106.7 165.3 254.7 198.3 117.2 169.9 130.6 208.7 136.4 133.6 387.2 313.9 147.2 300.9 202.5 183.9 137.9 136.9 112.5 231.8 104.0 113.5 258.1 142.2 248.2 193.8 156.1 265.3 184.3 450.2 234.6 175.5 317.8 181.0 128.3 190.3 185.1 178.2 111.5 161.9 151.5 158.1 143.1 72.7 108.4 195.7 290.0 230.8 133.9 319.9 262.2 261.3 276.5 204.4 181.4 294.1 191.2 77.2 110.8 97.1 114.4 107.9 103.1 73.2 91.8 103.5 105.2 62.9 70.0 81.8 60.2 101.1 112.6 89.4 106.8 145.6 82.2 84.6 75.0 104.2 86.3 85.8 85.9 85.8 88.1 75.7 82.5 87.8 420.1 54.5 95.5 51.6 163.7 148.6 119.3 149.0 127.5 78.0 85.0 75.8 71.3 75.8 114.8 64.4 39.6 188.9 166.1 192.3 101.8 199.8 119.0 88.2 120.5 267.5 81.3 89.8 35.0 199.0 430.2 108.3 226.8 126.4 134.3 90.8 172.1 45.3 210.2 89.2 24.6 181.3 105.8 83.9 313.8 253.8 106.2 165.6 138.7 29.0 165.1 75.8 135.9 21.1 32.5 297.6 183.5 103.4 170.5 120.1 117.9 89.7 78.2 84.4 78.9 94.4 138.6 72.4 73.5 138.1 133.7 242.4 164.2 123.0 186.1 156.1 CDC37L1 "CDC37B, FLJ20639, HARC" ENSG00000106993 "Cell division cycle 37 like 1" Q7L3B6 9 4679559-4708399 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 86.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "HDLM-2: 126.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021175 Approved Supported Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 44: HDLM-2 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA021175: AB_10959752" "unprognostic (1.18e-2)" "unprognostic (8.52e-2)" "unprognostic (2.63e-1)" "unprognostic (1.96e-1)" "unprognostic (1.61e-1)" "unprognostic (2.38e-2)" "unprognostic (3.66e-3)" "unprognostic (2.71e-2)" "unprognostic (9.89e-2)" "unprognostic (7.82e-3)" "unprognostic (2.78e-2)" "unprognostic (7.97e-2)" "prognostic favorable (2.66e-7)" "unprognostic (8.54e-2)" "unprognostic (1.91e-1)" "unprognostic (2.91e-2)" "unprognostic (4.28e-2)" 20.4 15.6 10.6 9.5 10.9 8.0 13.8 12.2 13.1 14.2 11.6 13.8 10.1 12.9 13.8 19.9 13.2 14.6 31.2 14.0 12.8 16.6 55.0 10.5 13.1 11.1 12.0 15.0 19.6 11.6 10.1 9.6 12.4 15.9 7.9 12.9 12.5 12.0 86.5 10.2 10.4 12.3 11.2 8.4 11.8 14.2 11.9 9.8 14.7 52.5 9.4 17.6 11.1 12.0 17.1 15.2 7.8 12.7 27.9 20.4 12.1 19.6 13.4 11.7 13.3 4.9 10.4 10.8 5.4 14.3 7.8 7.4 8.8 11.9 11.3 126.8 7.6 28.7 15.8 13.3 16.7 11.6 11.3 13.3 15.3 8.7 13.7 12.9 8.5 9.7 3.4 16.2 13.1 8.2 9.2 24.0 20.0 11.2 5.3 7.3 9.6 6.2 16.6 6.9 22.5 11.2 14.6 11.7 9.8 10.0 9.6 10.9 9.1 17.5 8.2 9.9 13.1 12.5 21.2 7.8 15.6 8.2 5.7 26.5 7.7 15.7 17.0 7.5 16.7 14.1 17.0 18.1 7.5 15.0 25.8 23.5 9.0 12.3 10.0 8.6 17.4 10.6 10.6 10.9 12.2 13.1 14.0 12.8 11.1 12.0 12.4 11.2 11.9 12.0 17.7 28.9 18.3 23.2 19.6 65.9 48.0 31.9 31.9 28.3 24.7 19.0 80.4 25.8 26.3 16.5 33.3 19.7 27.9 15.1 49.0 33.5 9.8 25.9 23.3 20.7 17.9 5.7 24.2 41.2 17.0 35.1 19.9 16.1 23.5 12.9 17.5 103.9 11.3 20.2 29.4 20.0 40.7 13.6 25.1 5.1 36.1 14.8 40.9 9.4 14.9 36.7 18.6 21.1 23.0 27.3 17.3 36.5 20.9 76.5 15.7 66.0 25.3 22.6 32.9 27.8 43.0 77.3 58.1 25.0 57.4 33.8 31.9 15.5 12.0 44.0 CDC42BPG "DMPK2, HSMDPKIN, kappa-200, MRCKgamma" ENSG00000171219 "CDC42 binding protein kinase gamma" Q6DT37 11 64823052-64844653 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 33.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 14.8;Gastric mucus-secreting cells: 23.0;Paneth cells: 18.3;Squamous epithelial cells: 19.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 8 "cerebellum: 9.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 29.3;HaCaT: 22.5;MCF7: 30.7;RT4: 18.4;SK-BR-3: 18.4;T-47d: 18.1" "Region enriched" "Detected in all" 4 "cerebellum: 10.5" "Low region specificity" "Detected in some" "HPA027382, HPA061836" Enhanced Supported Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA027382: AB_1846378, HPA061836: AB_2684622" "unprognostic (3.26e-2)" "unprognostic (1.58e-1)" "unprognostic (6.00e-2)" "unprognostic (2.60e-1)" "unprognostic (1.21e-1)" "unprognostic (2.50e-1)" "unprognostic (4.68e-1)" "unprognostic (5.27e-2)" "unprognostic (3.91e-2)" "unprognostic (3.65e-2)" "unprognostic (1.26e-1)" "unprognostic (1.81e-1)" "prognostic favorable (5.99e-13)" "unprognostic (2.60e-2)" "unprognostic (1.55e-1)" "unprognostic (2.14e-2)" "unprognostic (3.99e-3)" 0.5 4.9 0.2 1.4 0.3 2.1 4.8 9.7 1.2 5.4 5.5 8.8 10.6 0.4 2.0 26.5 3.8 2.8 0.4 0.4 0.3 7.7 0.9 7.8 1.3 0.4 0.7 2.2 14.1 6.4 11.0 4.2 1.0 8.5 4.5 0.3 17.7 3.7 0.2 33.7 9.3 0.2 0.3 1.8 12.2 3.3 0.3 2.4 6.0 0.0 2.0 5.8 13.0 0.3 8.9 1.2 0.8 0.0 0.0 0.0 29.3 0.0 0.0 0.0 0.0 11.7 7.5 0.1 4.3 0.0 0.4 22.5 1.3 8.8 0.0 0.4 3.6 0.7 5.3 3.8 0.0 0.3 2.2 0.0 10.9 0.1 0.1 0.1 0.1 3.5 6.1 0.1 0.0 30.7 0.2 1.7 2.7 8.3 1.3 1.3 0.5 4.3 5.5 18.4 15.6 0.7 2.8 18.4 0.5 4.3 18.1 0.4 0.1 0.0 3.1 0.1 0.1 2.1 2.2 2.2 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 9.7 1.2 0.4 0.3 0.4 0.7 1.0 0.3 0.3 0.3 1.0 9.6 7.9 0.0 1.2 6.5 2.3 3.6 9.6 0.0 5.1 5.8 1.8 2.8 9.6 1.8 0.0 6.4 1.7 14.8 0.0 2.4 0.6 13.2 0.7 0.4 3.6 0.8 0.1 6.2 4.9 0.7 23.0 7.9 1.3 0.4 0.0 0.0 1.0 0.0 0.1 4.8 2.0 0.0 0.4 0.8 0.0 1.3 0.0 0.0 1.2 0.8 1.0 0.0 0.1 2.9 18.3 0.0 0.1 1.6 12.4 0.5 9.5 0.0 0.0 2.2 0.8 1.7 1.3 19.3 8.1 6.7 1.4 0.6 5.7 3.4 CDCA3 "GRCC8, TOME-1" ENSG00000111665 "Cell division cycle associated 3" Q99618 12 6844793-6851292 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.5;retina: 66.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 56.3;Erythroid cells: 46.5;Extravillous trophoblasts: 74.1;Proximal enterocytes: 65.5;Spermatocytes: 71.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "T-reg: 4.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA026587 Approved Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA026587: AB_1846386" "unprognostic (3.05e-1)" "unprognostic (1.32e-1)" "unprognostic (9.85e-2)" "unprognostic (1.63e-2)" "unprognostic (2.42e-1)" "unprognostic (7.41e-2)" "prognostic unfavorable (6.51e-5)" "prognostic unfavorable (9.77e-5)" "unprognostic (3.88e-2)" "unprognostic (1.27e-1)" "unprognostic (1.80e-3)" "unprognostic (8.81e-2)" "unprognostic (0.00e+0)" "unprognostic (1.22e-1)" "unprognostic (1.09e-1)" "unprognostic (2.11e-1)" "unprognostic (4.94e-2)" 1.2 2.6 0.7 7.3 0.5 16.0 1.2 1.0 1.0 4.4 0.3 6.1 20.7 2.9 0.4 9.0 1.9 1.1 2.8 0.6 0.6 1.6 1.6 1.7 17.2 0.7 0.7 4.6 1.1 0.4 8.6 4.7 0.6 3.1 7.8 66.3 2.5 0.3 0.5 6.3 18.5 3.0 0.4 4.6 3.2 21.4 0.6 30.5 1.8 0.2 23.4 2.2 4.0 0.5 106.8 88.8 81.0 45.1 4.3 6.8 95.0 71.7 46.4 119.5 83.3 142.7 86.9 64.9 8.6 54.9 86.9 71.0 53.3 55.0 117.0 97.2 60.9 56.8 58.9 81.7 0.5 41.3 47.2 3.1 3.9 63.0 34.6 27.9 50.9 44.2 47.8 36.4 116.7 94.1 60.0 46.0 86.2 75.8 62.3 57.6 68.5 34.3 40.2 36.4 12.2 23.6 61.8 53.5 18.7 87.0 21.9 38.6 22.3 52.6 67.2 35.0 117.2 19.7 21.5 104.2 25.4 53.6 92.0 0.0 0.2 0.0 0.1 0.1 0.3 0.7 0.7 0.8 0.2 0.2 0.2 0.4 0.2 0.4 0.3 1.1 4.3 0.5 0.7 0.5 1.0 1.0 0.6 0.6 0.7 0.7 0.6 0.4 0.6 0.5 0.7 0.0 0.5 0.7 4.1 2.9 1.7 5.0 2.2 12.3 1.9 2.5 1.2 1.5 1.1 0.0 56.3 29.5 0.9 6.9 0.0 1.1 12.4 1.8 2.3 1.7 1.2 46.5 0.5 0.4 74.1 5.2 4.6 2.3 4.5 15.2 3.9 1.6 19.3 6.7 0.6 11.9 4.1 4.0 3.1 6.8 1.8 3.5 0.0 1.0 1.1 1.1 1.0 0.5 0.5 0.4 4.0 0.4 19.2 1.4 65.5 0.9 0.4 18.0 6.6 0.5 8.3 71.5 14.8 12.6 1.8 8.5 4.6 1.4 17.4 2.6 CDK3 ENSG00000250506 "Cyclin dependent kinase 3" Q00526 17 76000906-76005999 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 5.3;Breast myoepithelial cells: 5.0;Glandular and luminal cells: 5.2;Granulosa cells: 6.3;Ionocytes: 10.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" HPA007420 Uncertain Approved Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 18: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA007420: AB_1078490" "unprognostic (6.77e-2)" "unprognostic (1.26e-1)" "unprognostic (3.69e-2)" "unprognostic (1.87e-3)" "unprognostic (6.41e-2)" "unprognostic (1.10e-3)" "unprognostic (1.61e-2)" "unprognostic (1.56e-1)" "unprognostic (8.12e-3)" "unprognostic (1.34e-1)" "unprognostic (9.80e-5)" "unprognostic (1.19e-2)" "unprognostic (6.75e-7)" "unprognostic (4.25e-2)" "unprognostic (1.63e-2)" "unprognostic (4.68e-1)" "unprognostic (4.47e-4)" 12.7 11.0 11.4 7.7 11.8 10.6 12.2 11.5 13.8 15.7 12.0 14.9 10.4 11.5 10.7 11.1 13.7 10.3 8.4 11.3 12.2 18.4 34.8 14.2 10.5 12.0 11.7 15.9 15.1 4.8 19.7 8.9 12.2 25.7 10.1 6.9 13.6 8.4 3.6 24.7 14.7 7.6 11.5 21.9 12.2 15.6 11.8 5.8 19.5 3.3 10.5 10.8 13.3 13.6 5.5 7.5 13.5 6.5 7.3 9.0 26.1 4.6 4.6 8.0 7.4 7.0 11.0 6.5 4.5 5.7 4.6 11.6 10.2 4.1 5.6 3.3 14.1 12.7 17.8 7.3 6.7 5.9 14.9 8.7 10.8 7.3 5.1 13.0 6.9 4.1 5.6 4.5 4.3 12.1 6.3 21.8 6.3 3.8 8.4 10.4 5.2 7.2 6.9 15.8 8.4 22.0 3.8 12.0 3.2 14.2 17.4 10.9 5.5 16.4 9.6 5.4 6.7 9.9 7.2 6.2 5.4 5.5 3.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.1 11.4 11.8 11.5 13.8 11.3 12.2 12.0 11.7 12.2 11.5 11.8 13.6 4.3 0.0 0.0 0.0 0.5 2.7 0.0 4.0 0.0 0.0 5.3 5.0 0.3 0.0 2.2 0.0 0.0 0.0 3.1 0.0 1.9 2.0 0.0 2.9 3.9 1.4 0.0 0.0 0.0 2.3 0.0 1.3 0.0 5.2 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 4.4 0.0 0.0 1.4 3.6 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.5 0.0 0.0 1.2 2.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 2.7 0.0 1.0 2.8 0.0 0.0 CDKN3 "CDI1, KAP" ENSG00000100526 "Cyclin dependent kinase inhibitor 3" Q16667 14 54396849-54420218 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 207.0" "Cell type enhanced" "Detected in many" "Early spermatids: 2630.9;Late spermatids: 659.4;Spermatocytes: 606.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 18.8" "Group enriched" "Detected in all" 6 "NK-cells: 6.4;T-cells: 18.8" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005285, HPA039311, HPA058874" Enhanced Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "CAB005285: AB_2078884, HPA039311: , HPA058874: AB_2683842" "unprognostic (3.46e-2)" "unprognostic (9.95e-2)" "unprognostic (5.79e-2)" "unprognostic (6.78e-3)" "unprognostic (2.73e-1)" "unprognostic (6.08e-2)" "unprognostic (1.51e-3)" "prognostic unfavorable (4.52e-4)" "unprognostic (2.50e-3)" "unprognostic (2.85e-3)" "prognostic unfavorable (7.46e-4)" "unprognostic (5.89e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.71e-1)" "unprognostic (7.30e-2)" "unprognostic (7.92e-2)" "unprognostic (4.31e-2)" 3.4 1.6 2.8 12.2 2.7 43.4 3.4 5.0 4.2 2.2 3.4 13.9 12.4 2.8 0.4 10.2 1.3 2.9 5.3 2.9 3.1 2.0 2.4 2.1 28.4 2.5 2.7 1.3 1.1 0.5 1.6 6.7 3.3 1.6 16.9 2.6 3.3 0.7 3.0 5.9 12.6 7.4 2.1 4.9 5.0 207.0 3.5 30.9 1.7 4.1 30.0 5.8 4.1 2.6 276.7 102.5 74.0 78.2 12.5 15.3 46.5 63.1 97.0 135.8 146.9 81.8 136.5 139.9 44.4 96.7 135.9 195.9 114.6 78.3 245.6 169.5 59.3 65.8 69.0 126.8 10.1 86.2 47.6 5.4 4.9 84.3 138.3 44.4 88.4 129.8 36.1 162.2 159.8 186.9 118.1 67.9 27.9 254.7 216.4 72.7 66.6 29.7 70.5 56.9 30.6 42.0 118.7 67.4 52.5 54.6 142.9 69.4 33.0 59.2 195.8 91.7 155.0 38.6 47.4 91.4 98.6 120.4 110.9 0.0 1.3 1.3 1.6 1.7 0.7 2.1 5.5 4.8 1.8 0.9 2.9 2.3 1.0 6.4 1.2 1.5 18.8 3.1 2.8 2.7 5.0 4.2 2.9 3.1 2.5 2.7 3.3 2.1 3.5 2.6 1.4 0.0 0.0 0.7 10.5 9.3 4.3 9.7 4.6 3.2 6.4 11.6 9.7 0.0 2.4 1.8 2.1 42.6 2.7 7.3 0.0 3.5 2630.9 2.7 3.5 6.8 7.8 125.5 2.5 2.4 35.0 10.2 9.2 3.5 7.0 31.3 6.1 3.1 37.7 5.0 3.9 17.9 4.1 9.8 8.8 659.4 21.5 8.9 1.8 1.0 2.9 1.7 0.0 0.0 0.2 1.9 7.2 10.5 41.0 4.0 3.4 2.8 0.2 2.9 0.0 3.0 20.5 606.9 39.8 22.5 6.5 4.1 8.3 3.9 31.2 5.3 CDR2L HUMPPA ENSG00000109089 "Cerebellar degeneration related protein 2 like" Q86X02 17 74987632-75005800 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.1" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 23.2;Glandular and luminal cells: 28.9;Late spermatids: 30.9;Pancreatic endocrine cells: 26.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-BR-3: 61.8;U-138 MG: 62.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022015 Enhanced Approved Cytosol NA NA "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 44: Endometrium - Transcription" Cytosol "HPA022015: AB_1846462" "unprognostic (4.60e-2)" "unprognostic (2.52e-1)" "unprognostic (1.20e-2)" "unprognostic (3.85e-2)" "unprognostic (2.17e-1)" "unprognostic (7.36e-3)" "unprognostic (9.22e-2)" "unprognostic (1.78e-2)" "unprognostic (9.11e-2)" "unprognostic (2.11e-1)" "unprognostic (4.21e-2)" "unprognostic (1.84e-1)" "unprognostic (5.89e-2)" "unprognostic (1.15e-1)" "unprognostic (1.20e-1)" "unprognostic (1.13e-1)" "unprognostic (1.33e-1)" 9.0 5.9 17.7 2.7 34.2 0.1 8.0 40.8 21.7 10.3 19.4 10.5 22.4 12.7 0.9 6.7 6.8 8.8 19.6 14.9 25.2 16.5 1.5 12.9 0.9 42.2 33.9 3.2 4.3 2.6 6.0 7.0 38.6 7.4 1.4 1.7 8.3 5.1 2.1 4.6 11.5 5.4 28.4 1.8 15.1 7.8 35.5 0.5 4.7 3.2 0.7 9.5 6.9 45.1 15.0 42.1 9.2 19.3 15.8 13.8 4.2 21.3 9.4 12.2 15.5 25.1 13.5 0.0 21.9 37.3 11.0 39.2 11.0 5.2 8.0 0.3 18.6 0.1 26.2 16.3 9.1 1.7 0.7 8.1 8.1 29.0 3.0 8.7 26.5 3.2 6.5 2.1 13.0 13.5 2.0 1.6 12.0 35.3 20.6 6.9 14.0 6.5 32.5 9.3 15.8 53.4 26.8 61.8 2.0 5.5 17.1 2.8 19.0 62.4 13.1 39.7 13.6 2.0 1.3 0.0 17.3 5.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 17.7 34.2 40.8 21.7 14.9 25.2 42.2 33.9 38.6 28.4 35.5 45.1 9.4 16.0 0.0 0.7 0.0 6.0 2.1 2.3 4.6 3.9 7.3 5.8 4.1 11.5 3.4 5.5 0.0 2.9 0.8 0.3 15.6 12.9 7.5 23.2 12.8 12.5 4.9 0.0 2.6 6.9 0.5 6.8 14.8 28.9 0.0 0.7 7.9 0.4 1.6 0.0 5.3 4.2 2.0 0.6 4.6 30.9 2.8 1.6 1.8 5.6 0.6 0.9 0.0 2.5 16.8 26.0 0.0 2.6 0.4 8.1 19.5 2.7 4.0 2.5 0.0 4.2 6.8 3.1 1.7 2.6 2.4 2.3 0.5 1.6 2.3 14.1 CELA3A "ELA3, ELA3A" ENSG00000142789 "Chymotrypsin like elastase 3A" P09093 1 22001657-22012542 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2216 "pancreas: 262614.2" "Cell type enriched" "Detected in some" 56 "Exocrine glandular cells: 34710.4" "Cancer enriched" "Detected in some" 2497 "pancreatic cancer: 1481.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 28 "MOLT-4: 24.9" "HPA028086, HPA045650" Supported Approved Cytosol "Secreted to digestive system" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 1: Pancreatic cells - Digestion" Cytosol "HPA028086: AB_2672482, HPA045650: AB_2679407" "unprognostic (1.27e-1)" "unprognostic (2.71e-1)" "unprognostic (1.79e-1)" "unprognostic (6.32e-2)" "unprognostic (2.67e-1)" 20.0 4.5 0.0 3.0 0.0 2.8 11.6 0.0 0.0 12.9 0.0 4.5 21.3 4.1 0.0 7.4 3.0 0.1 44.6 0.0 0.0 4.1 13.5 3.0 6.0 0.0 0.0 118.5 262614.2 0.0 6.9 14.9 0.0 8.8 0.0 0.0 44.0 0.0 3.9 5.2 12.2 0.0 0.0 6.3 47.7 3.2 0.0 0.3 3.1 0.0 0.0 2.9 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 25.5 40.7 0.1 0.0 0.6 0.0 0.0 0.1 34710.4 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 197.1 0.3 2.4 0.0 0.0 94.0 0.0 0.0 0.0 0.0 619.0 1.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.8 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CELA3B "CBPP, ELA3B" ENSG00000219073 "Chymotrypsin like elastase 3B" P08861 1 21977022-21998642 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2088 "pancreas: 49621.1" "Cell type enriched" "Detected in some" 45 "Exocrine glandular cells: 14881.1" "Cancer enriched" "Detected in single" 1218 "pancreatic cancer: 408.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA028086, HPA045650" Supported Approved Cytosol "Secreted to digestive system" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 1: Pancreatic cells - Digestion" Cytosol "HPA028086: AB_2672482, HPA045650: AB_2679407" "unprognostic (2.89e-1)" "unprognostic (4.01e-3)" "unprognostic (6.53e-3)" "unprognostic (1.30e-1)" "unprognostic (1.29e-1)" "unprognostic (6.40e-2)" 9.0 1.8 0.0 0.6 0.0 0.8 4.5 0.0 0.0 4.4 0.0 1.8 6.2 1.6 0.1 2.6 1.2 0.0 8.4 0.0 0.0 1.6 5.0 1.2 1.1 0.0 0.0 23.7 49621.1 0.0 2.2 3.4 0.0 3.1 0.1 0.0 9.5 0.0 1.6 1.9 2.6 0.0 0.0 2.3 17.2 2.4 0.0 0.0 1.2 0.0 0.0 1.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.0 10.4 78.6 0.3 0.0 0.6 0.0 0.0 0.2 14881.1 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 309.9 0.9 0.9 0.0 0.0 60.4 0.0 0.0 0.0 0.2 325.6 16.0 0.7 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 CELSR2 "ADGRC2, CDHF10, EGFL2, Flamingo1, KIAA0279, MEGF3" ENSG00000143126 "Cadherin EGF LAG seven-pass G-type receptor 2" Q9HCU4 1 109249539-109275751 "G-protein coupled receptors, Predicted membrane proteins" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.8" "Cell type enhanced" "Detected in many" "Horizontal cells: 97.6;Oligodendrocytes: 48.1" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 8 "amygdala: 13.3;basal ganglia: 21.6;cerebral cortex: 44.6;hippocampal formation: 50.8;white matter: 26.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 47.9;HaCaT: 48.4;MCF7: 56.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013952 Uncertain Approved Cytosol NA NA 1300000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 62: Horizontal cells - Visual perception" Cytosol "HPA013952: AB_1846518" "unprognostic (4.46e-3)" "unprognostic (1.07e-2)" "unprognostic (3.00e-2)" "unprognostic (4.71e-2)" "unprognostic (2.19e-1)" "unprognostic (5.30e-2)" "unprognostic (3.51e-2)" "unprognostic (2.98e-1)" "unprognostic (1.33e-1)" "unprognostic (1.59e-2)" "unprognostic (1.47e-2)" "unprognostic (1.51e-1)" "unprognostic (1.94e-2)" "unprognostic (1.39e-1)" "unprognostic (2.32e-1)" "unprognostic (5.60e-2)" "unprognostic (5.16e-2)" 0.9 1.4 13.3 0.5 21.6 0.3 4.1 0.1 44.6 5.6 0.0 2.9 0.8 2.2 3.1 13.9 16.1 1.1 5.2 50.8 0.0 4.7 0.6 1.1 0.7 4.1 0.6 0.6 3.8 6.0 2.9 0.9 1.0 3.0 0.7 5.7 5.6 7.9 8.9 24.7 1.1 1.6 0.6 0.4 2.0 9.4 1.5 1.2 9.1 4.0 2.4 1.9 9.4 26.6 14.0 12.8 47.9 8.9 0.1 0.0 13.0 1.6 1.1 2.9 0.8 2.0 0.4 2.5 10.9 1.0 2.2 48.4 12.5 7.8 1.5 0.3 5.3 1.1 11.8 2.8 1.0 0.8 6.2 0.2 18.5 1.2 0.8 10.8 0.5 7.7 8.5 0.6 0.0 56.6 1.4 0.7 15.7 1.6 2.5 12.8 4.4 0.7 10.3 4.7 19.5 9.2 7.6 16.2 10.1 11.3 15.3 3.1 0.0 0.0 8.5 0.8 12.4 3.2 1.0 0.7 2.6 1.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 21.6 0.1 44.6 50.8 0.0 4.1 0.6 1.0 0.6 1.5 26.6 0.9 9.6 5.0 15.0 0.2 15.7 5.1 19.7 9.6 13.2 16.4 16.3 13.5 2.8 11.3 18.4 4.2 2.2 1.9 1.3 1.9 2.6 5.1 12.8 1.4 1.5 1.8 0.0 34.0 0.4 1.3 1.2 2.6 17.7 1.3 5.5 0.4 7.1 1.1 97.6 27.7 0.9 2.0 0.8 3.4 9.3 3.4 0.9 10.6 5.6 1.0 29.9 3.1 24.6 48.1 1.5 0.5 19.2 0.4 4.3 0.2 3.1 8.4 5.2 6.6 5.0 4.9 1.6 6.8 31.0 22.9 0.5 1.5 0.0 2.0 6.9 CES4A "CES8, FLJ37464" ENSG00000172824 "Carboxylesterase 4A" Q5XG92 16 66988589-67009758 "Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 16.9;skin 1: 13.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 44.4;Excitatory neurons: 53.6;Oligodendrocytes: 37.6;Respiratory ciliated cells: 47.1" "Cancer enhanced" "Detected in many" "renal cancer: 5.3" "Region enhanced" "Detected in many" "white matter: 10.2" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HDLM-2: 19.1;HMC-1: 5.2;PC-3: 4.5;SiHa: 7.8;SK-BR-3: 5.7;U-266/70: 5.9" "Not detected" "Not detected" HPA035701 Approved Approved Cytosol "Secreted - unknown location" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 30: Mammary glandular cells - Lactation" Cytosol "HPA035701: AB_10696357" "unprognostic (6.34e-2)" "unprognostic (2.09e-1)" "unprognostic (3.18e-1)" "unprognostic (3.26e-2)" "unprognostic (1.99e-1)" "unprognostic (6.20e-2)" "unprognostic (2.12e-2)" "unprognostic (2.04e-2)" "unprognostic (5.78e-3)" "unprognostic (3.93e-2)" "unprognostic (2.02e-3)" "unprognostic (3.15e-2)" "prognostic unfavorable (2.35e-6)" "unprognostic (1.20e-1)" "unprognostic (2.23e-1)" "unprognostic (1.74e-2)" "unprognostic (1.33e-3)" 3.6 1.5 1.2 0.8 2.6 1.2 2.5 0.1 2.5 1.0 0.0 0.6 0.8 0.5 3.9 1.0 16.9 0.8 2.4 2.3 1.0 2.6 8.4 1.5 0.7 1.7 0.2 1.0 1.1 3.1 3.6 1.0 1.2 0.9 0.7 0.8 4.3 2.1 4.9 13.6 0.8 0.3 0.0 0.5 1.4 0.8 0.8 0.7 2.7 0.2 0.9 1.2 0.7 10.2 0.2 1.5 0.1 0.0 0.9 0.8 0.0 0.4 0.7 0.1 0.0 0.0 2.3 0.0 0.0 1.5 0.0 0.7 0.0 0.2 0.0 19.1 0.0 0.0 1.2 0.0 0.1 0.0 5.2 1.8 3.5 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.8 4.5 0.2 0.0 1.1 0.0 0.3 1.4 0.9 7.8 5.7 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.0 5.9 2.2 0.0 1.4 0.0 0.0 0.0 1.4 0.0 0.5 2.5 0.5 0.6 1.0 0.5 0.8 0.0 0.9 0.2 0.0 0.0 3.5 1.2 0.3 0.7 1.2 2.6 0.1 2.5 2.3 1.0 1.7 0.2 1.2 0.0 0.8 10.2 0.4 0.0 11.4 2.0 3.5 5.4 5.7 5.0 3.4 23.1 44.4 7.7 2.8 4.3 7.3 5.5 14.6 4.7 3.9 4.1 1.9 0.9 1.7 9.9 1.4 1.0 9.0 0.0 53.6 1.6 0.9 3.9 3.1 11.1 9.5 4.9 1.1 22.1 5.6 0.0 29.7 1.8 4.1 4.1 2.1 1.2 13.7 3.2 0.0 4.7 5.7 8.3 4.1 6.6 37.6 0.9 9.7 12.8 1.3 3.5 5.8 1.5 47.1 15.3 0.0 1.5 1.8 32.1 11.8 4.1 5.3 4.5 3.3 13.5 3.5 7.5 CFAP57 "FLJ32000, WDR65" ENSG00000243710 "Cilia and flagella associated protein 57" Q96MR6 1 43172330-43254358 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 10.7;fallopian tube: 23.4;testis: 15.8" "Group enriched" "Detected in some" 7 "Early spermatids: 38.6;Endometrial ciliated cells: 62.4;Late spermatids: 26.7;Respiratory ciliated cells: 85.2;Spermatocytes: 25.4" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HaCaT: 2.8;HDLM-2: 1.8;TIME: 1.5" "Low region specificity" "Detected in many" "HPA002736, HPA028623" Enhanced Approved Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA002736: AB_2272982, HPA028623: AB_10603234" "unprognostic (1.15e-2)" "unprognostic (2.29e-3)" "unprognostic (2.16e-1)" "prognostic favorable (6.02e-4)" "unprognostic (2.50e-2)" "unprognostic (3.71e-1)" "unprognostic (2.42e-2)" "unprognostic (1.02e-1)" "unprognostic (1.39e-1)" "unprognostic (4.11e-1)" "unprognostic (2.05e-2)" "unprognostic (1.38e-1)" "unprognostic (3.46e-2)" "unprognostic (1.43e-1)" "unprognostic (1.80e-1)" "unprognostic (1.34e-2)" "unprognostic (7.78e-2)" 0.4 0.1 0.8 0.0 1.2 0.0 0.3 0.3 0.5 1.0 10.7 0.0 0.0 0.6 2.8 0.1 23.4 0.2 0.2 1.2 1.6 1.0 2.7 2.5 0.0 3.6 4.9 0.2 0.6 0.1 2.0 0.2 2.5 0.4 0.1 1.5 0.1 0.2 0.0 0.6 0.0 0.1 2.7 0.0 0.1 15.8 1.7 0.2 1.0 0.0 0.1 0.2 0.1 1.2 0.9 0.3 0.2 0.1 0.0 0.0 0.2 0.3 0.7 0.5 0.5 0.3 0.3 0.0 0.3 1.0 0.3 2.8 0.2 0.3 1.1 1.8 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.1 0.5 0.5 0.1 0.7 0.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 1.2 0.2 0.3 0.1 0.3 0.0 0.3 0.3 0.6 0.0 1.5 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.8 1.2 0.3 0.5 1.2 1.6 3.6 4.9 2.5 2.7 1.7 1.2 0.2 6.4 0.5 1.0 0.0 0.0 0.2 0.0 0.0 0.6 0.3 0.3 0.5 0.0 5.6 0.0 6.2 0.9 0.0 0.2 0.0 0.2 38.6 62.4 0.6 0.3 0.0 0.0 3.5 0.2 0.1 0.6 0.0 1.2 0.0 0.1 1.1 0.5 0.1 1.7 1.2 0.0 0.0 0.0 0.0 26.7 0.9 0.2 0.0 0.0 2.1 0.6 0.0 0.0 1.1 0.3 0.0 0.7 0.0 0.1 0.7 1.9 85.2 1.2 0.0 0.0 0.1 25.4 6.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 CFAP77 "C9orf171, FLJ46082" ENSG00000188523 "Cilia and flagella associated protein 77" Q6ZQR2 9 132410043-132573319 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 11.5;fallopian tube: 29.7;testis: 19.3" "Cell type enhanced" "Detected in some" "Early spermatids: 127.1;Endometrial ciliated cells: 58.4;Late spermatids: 47.6;Respiratory ciliated cells: 36.5;Spermatocytes: 25.5" "Cancer enhanced" "Detected in some" "endometrial cancer: 5.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SH-SY5Y: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021329, HPA024647, HPA061069" Enhanced Approved Cytosol NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA021329: AB_1848950, HPA024647: AB_10601126, HPA061069: AB_2732657" "unprognostic (7.28e-4)" "unprognostic (5.68e-2)" "unprognostic (5.25e-2)" "prognostic favorable (7.31e-4)" "unprognostic (1.70e-2)" "unprognostic (1.74e-1)" "unprognostic (3.01e-1)" "unprognostic (2.31e-2)" "unprognostic (1.34e-1)" "unprognostic (1.54e-1)" "unprognostic (1.77e-1)" "unprognostic (2.41e-3)" "unprognostic (2.65e-2)" "unprognostic (2.59e-2)" "unprognostic (1.39e-1)" "unprognostic (7.95e-2)" 0.0 0.0 1.2 0.0 1.0 0.0 0.0 2.0 0.1 1.2 11.5 0.0 0.0 0.5 0.2 0.0 29.7 0.0 2.4 1.0 1.5 0.1 0.0 2.1 0.0 4.1 6.0 0.0 0.1 0.0 0.6 0.0 3.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 19.3 1.4 0.2 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.5 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.0 2.0 0.1 1.0 1.5 4.1 6.0 3.1 3.3 1.4 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 127.1 58.4 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.6 0.3 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 36.5 3.8 0.0 0.0 0.0 25.5 3.5 0.0 0.0 0.1 0.1 0.1 0.0 0.1 CFL1 CFL ENSG00000172757 "Cofilin 1" P23528 11 65823022-65862026 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013086, CAB033687, CAB037077, HPA053761" Approved Supported Cytosol NA NA 290000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "CAB013086: AB_2533565, CAB033687: AB_1121774, CAB037077: AB_1078547, HPA053761: AB_2682251" "unprognostic (1.14e-1)" "unprognostic (2.37e-2)" "unprognostic (7.69e-3)" "unprognostic (4.32e-3)" "unprognostic (3.14e-2)" "unprognostic (2.09e-2)" "prognostic unfavorable (1.73e-5)" "unprognostic (1.59e-3)" "unprognostic (2.52e-1)" "unprognostic (5.88e-3)" "unprognostic (6.57e-3)" "unprognostic (2.09e-1)" "unprognostic (6.19e-3)" "unprognostic (1.72e-2)" "unprognostic (1.82e-1)" "unprognostic (1.49e-1)" "unprognostic (2.06e-1)" 609.5 435.4 578.8 932.7 598.8 1322.1 514.5 590.1 661.2 451.5 475.3 1145.1 1169.2 713.1 343.2 706.0 481.5 413.6 501.9 637.3 599.8 612.5 471.0 683.4 987.6 626.4 571.5 344.7 264.6 301.8 340.6 479.2 622.1 440.6 990.3 208.9 453.1 457.6 261.9 503.1 1120.7 847.3 608.3 775.2 633.8 267.4 632.2 939.6 370.9 230.6 1100.5 682.9 471.2 695.4 2284.3 1783.6 1908.5 1529.8 1142.6 1157.0 1031.6 2309.7 1942.4 2457.5 1460.7 1012.4 1815.2 1700.8 1755.3 2925.7 1780.5 1623.2 1389.2 2103.8 1824.9 1869.0 718.2 2185.8 1271.2 1162.1 1222.6 1890.2 2854.6 1339.3 1412.4 2166.7 1108.0 1494.0 2663.1 1099.4 1037.6 1648.5 2635.7 2133.0 2739.4 2965.4 2095.8 1985.4 1432.7 2050.3 941.1 2181.9 1847.8 1468.6 952.7 2106.6 1250.6 1733.6 1682.2 1053.4 2104.1 1427.8 2330.5 2087.3 1603.5 2672.6 2194.0 1193.1 2065.2 2251.0 2146.2 1161.7 2004.4 1690.2 2720.0 2973.1 2534.0 2955.4 1964.6 1561.4 1992.5 2296.2 3343.8 1527.0 1459.3 1905.2 2946.2 1961.1 3255.3 2558.6 2696.1 6842.2 578.8 598.8 590.1 661.2 637.3 599.8 626.4 571.5 622.1 608.3 632.2 695.4 805.5 246.8 223.0 24.5 890.8 1349.3 1253.3 1197.1 598.8 198.5 655.2 646.0 74.8 459.0 595.7 520.5 58.4 1239.8 1439.8 2052.9 892.1 2114.0 459.4 376.6 648.1 918.4 779.0 557.7 38.8 1965.0 2470.6 579.0 642.8 603.3 598.2 527.4 698.2 436.3 2911.0 203.6 30.3 1448.8 891.1 1185.5 1706.6 373.2 352.2 1474.2 985.4 38.4 2903.8 478.3 2075.2 22.6 62.0 3082.4 1894.7 502.9 639.1 991.2 2279.4 1246.5 295.5 118.0 420.7 448.2 1184.3 177.4 412.8 703.8 1267.4 1732.4 1276.2 621.7 1315.3 1383.3 CGB1 ENSG00000267631 "Chorionic gonadotropin subunit beta 1" A6NKQ9 19 49035569-49036895 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "pancreas: 2.7;pituitary gland: 4.3" "Cell type enriched" "Detected in single" 77 "Syncytiotrophoblasts: 69.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HMC-1: 17.7" "HPA038925, HPA038934" Uncertain Approved Cytosol "Secreted to blood" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA038925: AB_2676272, HPA038934: AB_2676277" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.0 17.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.4 0.0 3.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 69.9 0.0 0.0 0.0 0.0 CGB2 ENSG00000104818 "Chorionic gonadotropin subunit beta 2" Q6NT52 19 49031890-49033238 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.6" "Cell type enriched" "Detected in some" 6 "Syncytiotrophoblasts: 40.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HMC-1: 29.9;U-266/70: 12.1;U-266/84: 15.6" "HPA038925, HPA038934" Supported Approved Cytosol "Secreted in other tissues" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA038925: AB_2676272, HPA038934: AB_2676277" "unprognostic (3.05e-2)" 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.5 0.1 0.4 0.2 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.8 0.7 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 4.1 0.0 0.5 0.0 0.1 0.3 0.0 29.9 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.3 0.1 0.0 0.0 0.3 0.8 0.0 3.9 12.1 15.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.2 0.2 0.4 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 1.5 1.8 0.0 0.0 40.0 0.0 0.0 0.0 0.0 CGB3 CGB ENSG00000104827 "Chorionic gonadotropin subunit beta 3" P0DN86 19 49022869-49024333 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "placenta: 9.8" "Cell type enriched" "Detected in some" 7 "Syncytiotrophoblasts: 865.9" "Group enriched" "Detected in some" 5 "pancreatic cancer: 2.9;testis cancer: 4.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 20 "BEWO: 65.8" "CAB000042, CAB010884, HPA038925, HPA038934" Enhanced Approved Cytosol "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "CAB000042: , CAB010884: AB_259037, HPA038925: AB_2676272, HPA038934: AB_2676277" "unprognostic (1.39e-1)" "unprognostic (7.88e-2)" "unprognostic (6.92e-2)" "unprognostic (1.04e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.3 0.0 2.1 9.8 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.3 0.0 0.0 65.8 0.0 0.0 0.0 0.0 0.0 1.1 0.3 0.1 0.2 0.1 0.0 0.1 0.0 0.0 1.4 0.6 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.6 0.5 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.3 0.2 0.3 0.0 0.3 0.2 0.1 0.4 0.0 0.0 2.1 0.7 0.0 0.0 0.1 0.4 0.0 3.3 1.3 0.9 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 118.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 865.9 0.0 0.0 0.0 0.0 CGB5 HCG ENSG00000189052 "Chorionic gonadotropin subunit beta 5" P0DN86 19 49043848-49045311 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "pituitary gland: 8.7;placenta: 25.6" "Cell type enriched" "Detected in some" 4 "Syncytiotrophoblasts: 19.7" "Cancer enhanced" "Detected in some" "pancreatic cancer: 10.0;testis cancer: 5.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "BEWO: 120.1;U-251 MG: 53.2" "HPA038925, HPA038934" Supported Approved Cytosol "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA038925: AB_2676272, HPA038934: AB_2676277" "unprognostic (1.38e-1)" "unprognostic (1.68e-1)" "unprognostic (1.51e-3)" "prognostic unfavorable (1.18e-5)" "unprognostic (1.07e-1)" "prognostic unfavorable (9.47e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.1 8.7 25.6 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.8 0.4 0.0 0.0 0.0 0.0 120.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 3.5 0.0 0.0 0.0 0.1 2.2 0.0 53.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.7 0.0 0.0 0.0 0.0 CGB7 CG-beta-a ENSG00000196337 "Chorionic gonadotropin subunit beta 7" P0DN87 19 49054275-49058860 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "prostate: 3.2;skin 1: 3.9" "Group enriched" "Detected in some" 5 "Pancreatic endocrine cells: 16.5;Syncytiotrophoblasts: 58.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.7;HaCaT: 3.1;hTCEpi: 3.2;U-251 MG: 7.5" "HPA038925, HPA038934" Supported Approved Cytosol "Secreted in other tissues" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA038925: AB_2676272, HPA038934: AB_2676277" "unprognostic (9.53e-2)" "unprognostic (1.99e-1)" "unprognostic (1.87e-1)" "unprognostic (3.53e-1)" "unprognostic (4.60e-5)" "unprognostic (2.64e-1)" "unprognostic (2.46e-1)" "unprognostic (8.37e-2)" "unprognostic (2.88e-2)" "unprognostic (4.80e-2)" "unprognostic (8.83e-4)" "unprognostic (1.54e-1)" "unprognostic (3.89e-8)" "unprognostic (1.63e-2)" "unprognostic (1.94e-1)" "unprognostic (2.05e-1)" "unprognostic (9.28e-2)" 0.1 0.1 0.1 0.0 0.0 0.0 0.6 0.1 0.3 1.1 0.2 0.0 0.1 0.1 0.1 2.4 0.6 0.0 0.1 0.2 0.1 0.2 0.0 0.6 0.0 0.1 0.3 0.1 0.7 0.0 1.5 0.4 0.1 3.2 0.0 0.0 1.1 0.4 2.2 3.9 0.0 0.0 0.1 0.1 0.0 1.1 0.1 0.2 0.2 0.1 0.0 1.1 1.8 0.1 2.2 0.3 0.1 1.0 0.0 0.0 2.7 0.3 0.0 0.6 0.8 0.5 1.8 0.0 0.1 0.5 1.2 3.1 0.0 2.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 3.2 0.2 0.4 1.0 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 1.0 0.0 0.0 1.1 0.6 0.1 0.0 1.5 1.5 0.0 7.5 0.2 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.2 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.2 0.0 0.5 0.0 0.0 0.6 0.1 0.6 1.8 0.0 0.1 0.3 0.4 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 1.2 0.4 0.3 0.0 58.7 0.0 0.0 0.0 0.1 CGB8 ENSG00000213030 "Chorionic gonadotropin subunit beta 8" P0DN86 19 49047638-49049106 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "placenta: 18.8" "Cell type enriched" "Detected in some" 6 "Syncytiotrophoblasts: 44.3" "Cancer enriched" "Detected in some" 4 "testis cancer: 5.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "BEWO: 157.9;U-251 MG: 57.2" "HPA038925, HPA038934" Supported Approved Cytosol "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA038925: AB_2676272, HPA038934: AB_2676277" "unprognostic (3.35e-2)" "unprognostic (1.72e-1)" "unprognostic (7.44e-3)" "unprognostic (4.70e-1)" "unprognostic (1.67e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 18.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.1 1.2 0.0 0.0 0.0 0.0 157.9 0.0 0.0 0.6 0.0 0.0 5.3 0.0 0.1 1.0 4.0 1.3 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 10.1 0.2 0.6 0.0 2.8 7.1 0.7 57.2 0.1 0.2 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.3 0.0 0.0 0.0 0.0 CHAC2 GCG1 ENSG00000143942 "ChaC glutathione specific gamma-glutamylcyclotransferase 2" Q8WUX2 2 53767804-53775196 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 44.0;Plasma cells: 27.0;Spermatocytes: 47.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049235 Approved Approved Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA049235: AB_2680686" "unprognostic (2.22e-1)" "unprognostic (1.31e-1)" "unprognostic (2.11e-2)" "unprognostic (3.91e-3)" "unprognostic (1.61e-2)" "unprognostic (4.74e-3)" "prognostic unfavorable (3.80e-7)" "unprognostic (5.52e-2)" "unprognostic (1.74e-2)" "unprognostic (1.30e-2)" "unprognostic (1.36e-2)" "unprognostic (3.09e-2)" "unprognostic (4.28e-6)" "unprognostic (1.52e-1)" "unprognostic (1.79e-1)" "unprognostic (1.22e-1)" "unprognostic (2.55e-1)" 5.0 4.4 1.6 4.8 1.7 6.9 2.1 2.4 2.4 1.2 0.9 4.4 7.3 1.1 2.6 4.5 0.7 1.3 2.5 1.6 2.0 2.9 4.4 1.4 6.6 1.6 1.6 0.6 1.9 1.3 1.6 1.1 1.5 1.7 3.7 3.7 1.7 1.5 4.9 1.2 4.5 2.2 1.3 4.2 4.5 5.4 1.8 4.9 1.0 4.7 6.5 3.2 2.2 1.4 39.9 13.0 13.5 12.1 6.7 3.3 2.9 17.9 3.6 12.5 14.8 9.1 10.0 33.5 25.3 7.8 18.8 14.0 31.1 21.3 21.7 71.3 27.1 26.6 16.3 15.0 10.2 31.8 11.6 4.2 6.2 23.2 17.5 3.3 24.8 23.0 27.8 19.2 16.6 13.0 38.0 26.5 17.5 17.1 23.1 28.6 28.9 34.2 17.3 10.6 16.8 4.7 20.7 15.3 8.7 8.1 9.3 12.5 11.0 7.3 26.1 28.2 29.3 18.9 26.1 28.8 9.9 39.5 10.2 1.3 0.3 0.8 3.5 0.7 3.7 4.3 3.8 3.9 0.8 4.4 4.3 4.1 1.0 1.1 0.5 1.8 3.9 1.9 1.6 1.7 2.4 2.4 1.6 2.0 1.6 1.6 1.5 1.3 1.8 1.4 2.3 0.0 1.1 2.0 11.7 3.4 3.7 7.4 0.6 1.6 2.2 2.0 3.0 7.2 4.1 1.8 0.0 1.9 5.1 3.4 11.7 5.4 13.1 2.2 1.0 3.0 0.0 44.0 4.8 8.0 0.9 1.6 10.2 2.2 1.3 1.5 3.3 7.6 7.8 1.7 4.3 4.6 2.0 1.9 3.0 3.5 2.8 1.7 3.6 1.0 5.8 5.7 8.2 5.0 2.1 7.9 1.4 4.1 27.0 4.1 3.7 9.8 1.9 6.8 0.0 2.4 3.1 47.0 6.6 5.5 3.4 0.4 5.3 5.1 10.6 4.0 CHKB "CHETK, CHKL" ENSG00000100288 "Choline kinase beta" Q9Y259 22 50578959-50601455 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Kinase, Transferase" "Congenital muscular dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 19.1;RPMI-8226: 19.8" HPA018797 Approved Approved Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 3: Monocytes - Immune response regulation" Cytosol "HPA018797: AB_1846666" "unprognostic (6.03e-4)" "prognostic favorable (4.66e-4)" "unprognostic (4.31e-2)" "unprognostic (2.63e-2)" "unprognostic (2.14e-1)" "unprognostic (1.42e-2)" "unprognostic (3.25e-3)" "unprognostic (1.70e-2)" "unprognostic (2.00e-1)" "unprognostic (7.84e-2)" "unprognostic (5.23e-3)" "unprognostic (5.43e-2)" "prognostic unfavorable (1.56e-5)" "unprognostic (1.33e-1)" "unprognostic (9.54e-2)" "unprognostic (1.30e-2)" "unprognostic (2.18e-3)" 14.1 13.0 10.3 0.7 10.3 12.1 13.4 10.5 16.8 10.6 12.2 10.5 3.3 9.5 12.0 11.1 12.0 1.5 11.5 10.1 10.8 13.2 9.4 13.3 4.3 10.5 11.0 8.6 7.7 17.7 14.3 7.2 10.6 12.0 4.8 1.6 11.9 7.2 8.3 11.6 10.7 5.3 10.7 18.1 11.6 14.5 11.0 9.2 12.6 11.7 9.8 11.7 11.1 10.8 4.2 1.3 0.5 1.6 6.7 5.9 10.8 7.3 16.7 4.7 3.1 1.4 2.1 2.1 4.2 3.8 2.4 0.0 1.5 2.0 1.0 0.3 5.4 3.1 2.2 2.3 19.1 2.5 4.8 2.0 6.5 0.6 8.1 4.5 17.1 5.5 1.8 0.3 12.4 5.3 2.0 8.6 0.7 7.0 1.9 3.5 1.8 19.8 11.5 2.0 2.0 3.2 3.0 7.3 5.9 0.2 1.1 2.8 6.9 0.0 1.7 0.0 2.2 7.4 0.0 3.0 2.3 0.4 3.4 12.0 39.5 27.0 26.4 38.4 25.7 24.0 24.2 27.6 35.7 23.6 22.6 20.8 9.6 37.0 26.1 34.1 33.4 32.6 10.3 10.3 10.5 16.8 10.1 10.8 10.5 11.0 10.6 10.7 11.0 10.8 16.7 6.4 28.2 0.0 13.6 4.8 2.3 6.9 8.6 4.8 10.0 7.4 7.7 20.0 12.7 7.3 4.2 8.8 14.0 18.4 3.9 30.6 11.6 3.9 3.4 8.0 15.7 9.0 0.0 23.8 14.1 8.6 19.9 3.3 19.0 2.5 10.4 5.4 14.6 8.4 0.0 19.3 12.2 16.6 9.2 30.5 2.5 10.0 3.6 0.0 48.4 3.3 14.4 0.0 0.0 23.5 24.2 3.0 14.6 2.1 29.3 5.5 11.2 6.0 6.6 2.4 6.8 12.6 10.0 14.5 6.3 8.5 11.2 2.8 17.3 2.2 CHMP2B "CHMP2.5, DKFZP564O123, VPS2B" ENSG00000083937 "Charged multivesicular body protein 2B" Q9UQN3 3 87227271-87255556 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 445.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035069, HPA052754" Uncertain Approved Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA035069: AB_10602798, HPA052754: AB_2681936" "unprognostic (7.83e-3)" "unprognostic (7.45e-2)" "unprognostic (2.01e-3)" "unprognostic (4.05e-2)" "unprognostic (1.51e-1)" "unprognostic (2.35e-1)" "unprognostic (1.02e-2)" "unprognostic (1.52e-2)" "unprognostic (9.78e-2)" "unprognostic (8.69e-2)" "prognostic unfavorable (2.11e-5)" "unprognostic (5.76e-2)" "prognostic favorable (1.74e-6)" "unprognostic (6.52e-2)" "unprognostic (2.29e-1)" "unprognostic (6.41e-3)" "unprognostic (1.21e-1)" 26.0 24.2 15.7 22.8 20.2 42.7 26.3 22.3 22.2 28.9 16.2 41.6 38.5 29.5 22.5 35.2 22.6 28.8 27.0 15.1 18.2 29.6 34.5 22.9 21.9 25.1 21.0 24.9 29.2 24.3 30.4 25.0 24.1 34.9 37.5 15.3 24.9 27.7 35.3 26.4 40.8 29.6 23.7 22.1 31.1 16.1 20.3 17.2 43.1 28.0 21.6 42.3 29.7 31.2 68.4 71.6 25.4 17.4 45.0 38.4 29.7 52.8 71.2 45.1 57.1 57.0 115.0 25.3 36.7 60.1 38.6 35.0 31.6 37.6 56.0 41.7 34.7 29.5 24.6 25.4 39.2 44.9 42.5 29.3 63.2 42.9 58.3 42.6 35.8 29.6 17.3 36.7 50.2 53.2 41.1 18.3 32.4 91.1 65.5 21.4 31.0 26.1 36.0 71.3 9.7 10.8 54.2 45.6 91.4 28.8 40.6 13.7 30.6 42.9 36.5 445.0 37.7 37.7 56.3 41.6 47.6 24.8 30.9 124.7 50.7 136.7 27.3 65.2 37.3 49.6 34.6 34.8 55.1 53.4 32.0 32.4 96.8 31.4 67.8 31.3 52.4 37.8 15.7 20.2 22.3 22.2 15.1 18.2 25.1 21.0 24.1 23.7 20.3 31.2 56.2 83.3 68.7 11.4 58.7 132.0 254.5 90.0 53.5 19.9 59.8 52.1 68.8 62.9 85.0 49.7 4.2 75.4 45.7 268.7 138.9 170.6 6.8 86.7 45.2 54.4 46.7 36.2 14.1 261.2 187.0 68.9 48.4 86.9 74.1 27.1 48.5 60.8 86.9 37.0 15.1 80.3 73.2 61.9 87.6 7.5 66.2 72.6 40.9 9.4 62.0 213.9 42.2 10.6 36.0 237.4 241.3 96.3 30.0 226.0 101.7 145.8 90.5 16.3 72.3 58.5 57.5 78.7 76.7 62.8 145.6 180.9 52.9 38.1 81.3 330.3 CHN1 "ARHGAP2, CHN, DURS2, n-chimerin, RhoGAP2" ENSG00000128656 "Chimerin 1" P15882 2 174798809-175005381 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Neurogenesis "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 772.6" "Cell type enhanced" "Detected in many" "Astrocytes: 195.2;Excitatory neurons: 596.4;Inhibitory neurons: 111.7;Microglial cells: 97.4;Oligodendrocyte precursor cells: 149.8" "Cancer enhanced" "Detected in all" "glioma: 18.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 6.5;memory CD8 T-cell: 2.1;T-reg: 8.0" "Lineage enriched" "Detected in single" 18 "T-cells: 8.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 186.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036111 Approved Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA036111: AB_10671241" "unprognostic (3.18e-3)" "unprognostic (4.19e-2)" "unprognostic (9.69e-2)" "unprognostic (3.42e-3)" "unprognostic (1.92e-1)" "unprognostic (2.65e-2)" "unprognostic (7.45e-2)" "unprognostic (9.14e-2)" "unprognostic (3.71e-2)" "unprognostic (1.34e-2)" "unprognostic (5.29e-2)" "unprognostic (2.95e-1)" "prognostic unfavorable (5.07e-4)" "unprognostic (7.31e-3)" "unprognostic (4.07e-1)" "unprognostic (2.08e-2)" "unprognostic (9.46e-2)" 11.8 13.3 368.6 7.3 445.9 0.8 10.5 194.0 772.6 9.2 170.6 10.2 3.3 7.9 38.3 6.9 6.5 11.1 15.1 492.6 241.5 4.7 2.1 19.6 21.5 210.2 225.4 5.8 4.2 43.4 36.3 38.6 210.5 17.0 5.1 39.5 3.2 9.6 2.7 3.8 7.5 13.1 192.4 5.5 7.1 21.3 239.1 3.1 10.2 3.7 18.7 8.7 6.7 422.8 0.4 17.4 57.6 16.3 14.7 67.4 0.4 45.6 186.7 65.1 97.0 0.3 5.4 0.5 1.6 71.8 39.9 2.0 68.0 1.9 30.3 1.3 32.9 11.1 20.1 3.8 34.4 6.4 1.7 53.6 1.9 31.6 11.1 16.1 33.6 30.0 0.7 1.9 57.2 11.8 29.3 2.5 71.7 2.6 23.7 8.2 70.3 0.8 0.9 0.6 71.3 76.3 41.3 0.5 7.3 36.0 3.2 2.2 10.1 26.8 3.9 9.8 20.6 6.4 33.7 0.7 6.7 0.4 6.6 0.4 0.1 0.1 0.3 0.1 0.8 0.2 6.5 2.1 0.0 0.1 1.3 0.4 0.4 0.2 0.2 0.3 8.0 1.0 368.6 445.9 194.0 772.6 492.6 241.5 210.2 225.4 210.5 192.4 239.1 422.8 15.4 3.2 1.9 195.2 1.6 4.5 0.3 0.0 0.0 85.1 7.3 1.4 6.2 1.5 2.6 3.7 27.1 1.2 0.5 0.1 0.0 0.3 24.1 5.3 5.6 17.9 2.4 0.0 596.4 0.6 1.1 28.4 2.0 3.6 0.0 5.1 10.4 0.5 2.7 77.4 111.7 0.0 0.0 0.0 4.0 23.2 3.1 0.9 7.2 97.4 0.0 59.1 0.0 149.8 88.1 0.6 0.0 5.3 1.3 0.6 0.0 0.3 1.0 14.1 13.1 23.8 27.3 17.8 23.6 0.1 3.7 2.1 12.5 5.1 0.2 0.3 CHORDC1 "CHP-1, CHP1" ENSG00000110172 "Cysteine and histidine rich domain containing 1" Q9UHD1 11 90200429-90223077 "Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 94.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041040 Approved Approved Cytosol NA NA 160000 "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "HPA041040: AB_10794185" "unprognostic (2.29e-3)" "unprognostic (3.08e-1)" "unprognostic (5.26e-2)" "unprognostic (3.10e-2)" "unprognostic (3.27e-1)" "unprognostic (1.85e-2)" "prognostic unfavorable (4.93e-7)" "unprognostic (1.84e-1)" "unprognostic (1.04e-3)" "unprognostic (5.27e-3)" "unprognostic (2.25e-1)" "unprognostic (2.73e-2)" "prognostic unfavorable (1.88e-4)" "unprognostic (4.23e-2)" "unprognostic (2.63e-1)" "unprognostic (2.59e-1)" "unprognostic (1.52e-1)" 20.2 19.8 17.4 10.5 18.4 10.7 12.0 18.2 94.5 16.2 18.6 14.0 5.4 15.3 8.4 17.5 14.5 7.1 21.7 19.6 20.7 15.9 21.7 18.1 13.4 18.8 18.4 25.4 12.9 5.0 22.3 12.2 18.7 15.4 6.9 7.7 12.3 7.2 18.0 10.3 12.4 6.9 18.4 16.5 14.2 13.7 18.9 10.6 16.9 13.1 13.7 17.0 17.2 26.4 28.1 74.8 26.0 17.0 24.7 14.9 39.6 34.1 11.6 34.9 29.3 113.9 21.9 49.3 54.0 15.1 60.8 35.0 76.7 17.3 38.7 42.4 37.3 46.6 45.1 55.7 19.0 35.0 29.6 5.5 22.9 29.4 33.8 18.7 26.9 28.5 71.8 19.9 41.5 13.9 32.2 45.9 29.9 96.0 63.3 49.2 15.5 29.3 28.5 12.7 24.8 10.2 37.3 28.8 13.8 29.7 49.0 16.6 24.0 25.4 51.1 35.5 40.6 9.4 80.0 38.9 7.3 49.9 22.1 8.6 8.0 8.9 12.0 13.6 13.1 13.1 13.0 12.7 12.7 11.5 13.6 13.2 2.4 16.5 9.2 9.8 17.9 11.2 17.4 18.4 18.2 94.5 19.6 20.7 18.8 18.4 18.7 18.4 18.9 26.4 49.4 19.2 27.4 18.6 55.5 70.7 164.8 20.1 32.5 45.1 33.2 31.8 30.7 12.8 29.3 11.0 135.5 41.3 62.1 30.1 11.7 23.8 93.9 112.7 75.0 48.2 68.8 25.7 65.7 16.1 76.5 50.2 20.4 93.9 87.0 34.0 15.7 14.8 39.2 65.6 60.0 32.7 22.4 19.2 109.2 57.1 32.6 61.7 28.4 30.0 30.5 22.9 39.1 46.8 81.5 20.9 28.5 31.2 42.9 97.5 10.7 25.3 48.0 53.7 13.1 32.6 71.0 98.1 47.0 26.5 81.8 50.9 104.9 51.6 37.0 89.6 CHST10 HNK-1ST ENSG00000115526 "Carbohydrate sulfotransferase 10" O43529 2 100391860-100417668 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 33.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 16.0;Astrocytes: 21.5;Muller glia cells: 16.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012884, HPA051545" Approved Approved Cytosol "Intracellular and membrane" NA NA 680000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol "HPA012884: AB_1846710, HPA051545: AB_2681529" "unprognostic (5.40e-3)" "unprognostic (3.62e-2)" "unprognostic (3.44e-2)" "unprognostic (2.03e-1)" "unprognostic (3.28e-1)" "unprognostic (1.30e-1)" "unprognostic (1.89e-2)" "unprognostic (1.44e-1)" "unprognostic (1.78e-1)" "unprognostic (4.54e-2)" "prognostic favorable (4.05e-4)" "unprognostic (8.02e-2)" "unprognostic (2.18e-1)" "unprognostic (1.78e-2)" "unprognostic (3.73e-2)" "unprognostic (3.06e-2)" "unprognostic (3.27e-1)" 4.3 6.7 26.5 4.2 28.2 3.2 5.1 24.3 33.6 7.1 18.8 6.3 2.3 11.5 13.3 4.2 9.7 5.5 11.0 27.2 23.2 4.3 1.2 8.1 4.4 24.6 26.4 12.7 5.6 9.6 11.5 8.2 23.2 8.0 2.4 9.4 6.1 5.2 6.0 2.2 3.6 12.0 24.8 5.0 4.4 6.1 28.6 5.7 10.0 8.3 5.4 5.5 3.7 25.1 0.2 14.6 28.4 14.6 8.5 11.9 14.2 16.7 11.8 22.4 14.3 0.3 8.5 20.4 14.1 10.1 39.6 0.0 20.2 2.2 14.3 29.1 21.2 10.5 8.3 23.1 10.1 21.5 26.5 8.8 2.7 10.6 2.0 10.7 17.8 19.5 31.0 0.1 9.7 4.8 19.1 16.8 42.0 0.2 17.7 13.6 17.6 0.2 6.2 6.4 30.5 24.9 1.2 0.1 23.3 20.0 7.8 29.0 16.4 15.5 24.5 11.7 15.7 0.0 0.1 21.2 19.0 18.7 18.6 0.0 0.0 0.0 1.3 0.0 0.4 0.8 0.2 1.0 0.2 0.6 0.3 0.7 0.0 0.0 0.0 1.1 0.0 0.5 26.5 28.2 24.3 33.6 27.2 23.2 24.6 26.4 23.2 24.8 28.6 25.1 2.8 16.0 3.1 21.5 4.4 0.9 1.1 0.3 0.6 9.7 2.4 2.0 6.3 1.5 4.4 1.8 0.0 5.4 2.3 0.0 3.9 3.5 1.5 2.7 6.7 4.9 1.8 3.0 10.7 2.9 10.5 5.0 0.0 6.2 0.0 6.5 0.4 0.0 6.2 6.7 7.5 0.0 0.0 0.8 1.1 0.4 2.1 1.3 0.0 6.5 3.2 16.7 1.0 12.5 5.9 2.2 0.0 5.3 2.3 1.5 0.0 1.1 0.7 4.8 0.0 3.7 3.5 1.5 5.1 0.3 0.6 1.4 3.4 8.5 0.1 0.2 CHURC1 "C14orf52, FLJ33064, My015" ENSG00000258289 "Churchill domain containing 1" Q8WUH1 14 64914361-64944591 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040072 Approved Approved Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Cytosol "HPA040072: AB_10963788" "unprognostic (2.94e-1)" "unprognostic (2.42e-1)" "unprognostic (1.59e-1)" "unprognostic (1.61e-1)" "unprognostic (1.80e-1)" "unprognostic (2.17e-1)" "unprognostic (2.19e-1)" "unprognostic (1.64e-2)" "unprognostic (4.64e-1)" "unprognostic (6.78e-3)" "unprognostic (2.12e-1)" "unprognostic (1.99e-1)" "unprognostic (3.51e-2)" "unprognostic (6.67e-2)" "unprognostic (3.04e-2)" "unprognostic (1.55e-1)" "unprognostic (1.26e-1)" 47.8 42.0 29.9 39.1 34.8 43.8 37.4 34.5 41.2 41.2 27.2 43.8 30.9 40.0 32.6 34.3 34.2 32.5 58.8 29.8 33.7 34.7 52.4 29.3 43.8 38.8 33.3 43.9 30.2 46.1 25.2 34.5 38.6 32.4 36.4 35.7 26.5 37.7 82.9 30.1 33.9 45.8 34.7 42.2 33.7 25.4 34.3 61.2 32.9 53.0 43.3 38.3 30.5 40.3 119.6 61.8 58.8 43.7 70.1 75.6 68.9 85.3 74.3 47.4 53.9 34.1 75.1 69.9 57.7 73.7 75.2 84.9 51.7 69.2 51.8 79.7 25.3 67.9 47.7 79.3 66.1 37.7 64.9 89.9 50.5 43.0 81.4 79.7 51.6 107.2 30.6 60.5 58.1 97.6 72.7 61.6 31.4 140.9 101.1 63.4 63.2 42.6 64.5 83.8 30.0 36.7 57.6 59.8 81.0 53.7 101.8 78.4 64.8 41.3 87.8 45.0 56.0 49.5 46.8 162.0 43.0 44.6 51.8 201.6 131.9 145.4 111.5 137.6 128.2 161.8 167.5 134.1 107.4 135.9 166.3 139.8 292.8 122.4 138.3 154.7 238.5 143.5 29.9 34.8 34.5 41.2 29.8 33.7 38.8 33.3 38.6 34.7 34.3 40.3 154.6 102.5 89.0 0.0 128.2 58.5 73.8 176.8 130.3 73.8 85.0 98.7 53.4 94.4 98.2 99.3 43.8 90.4 97.9 89.3 131.0 160.7 82.0 130.8 87.3 109.9 89.8 91.5 0.0 222.7 89.7 100.9 75.4 80.8 95.6 69.6 127.5 190.4 89.3 53.8 0.0 100.3 107.8 172.6 69.6 27.1 104.1 130.5 83.6 0.0 214.3 155.2 132.8 0.0 0.0 216.8 118.9 121.5 79.7 70.5 124.6 211.0 145.1 87.2 131.5 100.6 135.7 131.1 81.1 158.3 65.9 89.8 137.0 205.8 121.1 72.2 CIT "CITK, CRIK, KIAA0949, STK21" ENSG00000122966 "Citron rho-interacting serine/threonine kinase" O14578 12 119685791-119877320 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 87.6;Early spermatids: 72.8;Excitatory neurons: 147.0;Inhibitory neurons: 139.8;Oligodendrocyte precursor cells: 82.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019082, HPA048812, HPA075506" Uncertain Approved Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA019082: AB_1846803, HPA048812: AB_2680528, HPA075506: AB_2686752" "unprognostic (5.64e-2)" "unprognostic (5.00e-2)" "unprognostic (8.16e-2)" "unprognostic (5.12e-3)" "unprognostic (1.25e-1)" "unprognostic (3.55e-2)" "unprognostic (3.61e-6)" "unprognostic (6.02e-2)" "unprognostic (7.78e-2)" "unprognostic (4.42e-1)" "unprognostic (1.37e-3)" "unprognostic (4.88e-2)" "unprognostic (2.55e-3)" "unprognostic (8.56e-2)" "unprognostic (1.50e-1)" "unprognostic (1.70e-1)" "unprognostic (3.30e-1)" 0.7 2.2 13.5 1.6 26.2 6.3 0.6 0.0 19.9 0.9 0.0 2.1 1.2 0.4 0.0 2.5 0.5 0.5 0.6 15.2 5.4 2.5 0.3 1.8 1.5 0.2 5.0 0.3 0.2 0.1 1.6 1.4 0.4 0.5 2.5 3.4 0.8 0.2 0.5 1.6 1.9 0.9 0.9 3.0 2.2 4.8 14.2 6.8 0.6 0.3 2.3 0.5 1.3 6.6 26.2 20.6 21.7 15.3 2.4 6.3 10.4 22.0 19.1 21.8 16.6 14.5 10.3 18.4 10.0 14.2 9.3 14.6 14.4 9.5 32.1 13.6 7.5 25.7 13.2 7.1 0.3 12.7 20.6 0.9 1.2 23.7 14.8 7.3 15.5 19.9 14.5 15.2 19.5 12.2 22.4 14.0 10.4 8.7 12.5 19.3 39.8 6.3 5.0 11.1 15.5 8.4 31.9 6.5 16.0 9.6 23.2 10.6 11.5 21.9 21.4 17.2 22.7 9.9 12.6 14.2 16.8 12.5 35.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 13.5 26.2 0.0 19.9 15.2 5.4 0.2 5.0 0.4 0.9 14.2 6.6 4.1 6.4 13.0 8.5 1.2 3.3 0.7 1.0 0.6 8.2 1.8 1.5 1.8 0.0 5.6 9.2 87.6 3.5 0.6 1.1 0.0 0.2 72.8 2.4 2.1 2.7 1.8 12.8 147.0 0.8 4.8 2.2 3.1 3.6 1.3 10.5 1.1 0.7 3.6 0.0 139.8 4.4 6.1 3.7 0.8 44.1 1.2 2.0 3.6 7.5 0.0 15.4 1.0 82.4 18.7 0.2 0.1 1.2 4.1 0.4 0.8 7.5 1.7 15.2 0.0 0.6 3.3 33.2 4.2 7.7 1.3 1.0 2.2 4.3 4.4 1.0 CKB CKBB ENSG00000166165 "Creatine kinase B" P12277 14 103519667-103522833 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 694.7;intestine: 653.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 2767.4;Distal enterocytes: 4691.8;Distal tubular cells: 2281.3;Horizontal cells: 5042.4;Muller glia cells: 3639.8;Rod photoreceptor cells: 3789.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "non-classical monocyte: 290.8" "Lineage enriched" "Detected in many" 18 "monocytes: 290.8" "Cell line enhanced" "Detected in many" "CACO-2: 455.8;HEK 293: 1399.8;SCLC-21H: 792.2;SH-SY5Y: 352.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001254, CAB047313" Enhanced Supported Cytosol No No 38000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB047313: , HPA001254: AB_1078528" "unprognostic (9.97e-2)" "unprognostic (1.33e-3)" "unprognostic (4.25e-3)" "unprognostic (1.10e-1)" "unprognostic (7.63e-2)" "unprognostic (3.62e-2)" "unprognostic (1.64e-1)" "unprognostic (1.30e-1)" "unprognostic (4.24e-1)" "unprognostic (4.60e-2)" "unprognostic (2.68e-3)" "unprognostic (9.89e-3)" "prognostic favorable (4.02e-8)" "unprognostic (2.62e-1)" "unprognostic (1.10e-1)" "unprognostic (1.67e-2)" "unprognostic (2.13e-1)" 90.7 60.0 471.6 25.8 627.0 3.2 47.2 641.1 694.7 105.2 192.7 653.4 36.0 222.6 16.0 54.5 197.9 17.9 269.8 428.7 482.3 161.0 9.0 60.3 4.0 427.5 440.4 58.8 27.7 108.2 74.0 4.7 345.1 301.8 151.9 471.3 37.9 208.3 80.0 76.5 120.8 113.8 434.5 6.8 479.9 97.6 596.2 2.8 87.9 47.1 5.1 298.4 101.6 383.6 2.4 54.5 321.1 14.7 4.4 2.3 6.3 37.5 0.3 2.4 1.4 455.8 7.3 0.4 36.9 29.1 9.9 70.2 109.9 1.5 0.2 9.6 1399.8 111.0 242.1 165.4 16.6 0.7 87.9 14.7 0.6 3.9 0.8 3.3 0.0 5.1 198.7 3.7 4.8 20.0 2.3 3.9 109.1 48.3 213.6 13.9 6.8 275.9 65.9 2.5 792.2 352.2 65.3 10.6 25.2 21.6 21.1 40.9 2.2 1.5 56.3 4.7 147.3 21.1 2.7 7.2 6.4 2.1 14.1 2.4 0.5 14.6 0.3 28.5 0.4 0.0 0.2 0.1 16.4 0.2 0.1 0.5 1.0 0.2 290.8 0.0 0.7 6.0 471.6 627.0 641.1 694.7 428.7 482.3 427.5 440.4 345.1 434.5 596.2 383.6 14.8 195.5 103.5 515.8 13.5 153.7 296.2 257.6 56.3 2767.4 41.5 48.9 553.5 145.8 117.9 114.0 1909.9 4.4 3.4 4691.8 2281.3 127.6 445.8 773.2 205.7 60.8 467.1 9.9 178.0 42.5 11.7 96.6 359.4 408.5 28.6 476.1 74.6 9.2 8.2 5042.4 147.0 726.0 187.2 2.8 44.9 147.4 304.1 39.8 181.5 88.1 74.2 3639.8 0.0 93.5 161.2 131.4 1996.9 1089.3 6.6 279.8 9.5 118.0 456.1 3789.9 59.2 15.4 222.6 127.3 97.4 22.1 175.2 41.6 19.1 12.2 755.6 220.1 CLCN2 "ClC-2, CLC2, EJM6" ENSG00000114859 "Chloride voltage-gated channel 2" P51788 3 184346185-184361650 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 16.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 81.7;Proximal enterocytes: 27.4;Theca cells: 62.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009397, HPA014545, HPA024108" Approved Approved Cytosol NA NA "Cluster 45: Intestine - Brush border" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB009397: AB_2079256, HPA014545: AB_1846881, HPA024108: AB_1846883" "unprognostic (1.13e-1)" "unprognostic (4.01e-2)" "unprognostic (6.48e-2)" "unprognostic (5.11e-3)" "unprognostic (1.15e-1)" "unprognostic (2.53e-2)" "prognostic unfavorable (4.67e-8)" "unprognostic (1.72e-2)" "unprognostic (2.26e-1)" "unprognostic (1.23e-1)" "unprognostic (2.10e-1)" "unprognostic (2.50e-3)" "unprognostic (1.19e-1)" "unprognostic (4.40e-2)" "unprognostic (5.88e-2)" "unprognostic (4.60e-2)" "unprognostic (1.35e-1)" 1.4 5.1 2.2 1.8 3.1 1.0 1.6 3.1 3.0 3.0 1.6 16.2 9.2 3.6 3.8 1.7 2.4 7.5 1.2 2.0 2.4 3.0 1.7 1.2 0.7 3.4 3.0 4.0 4.5 3.4 2.8 1.0 2.7 2.3 10.8 0.6 2.8 2.9 0.9 1.6 8.4 1.6 2.9 1.5 2.2 10.6 3.3 1.3 2.7 0.5 0.9 2.1 2.0 4.3 8.9 3.2 2.5 6.9 2.2 1.8 5.8 2.9 1.7 3.1 2.0 16.8 3.0 3.0 8.2 1.6 8.0 15.1 3.6 3.5 0.9 2.8 4.2 2.7 7.0 7.7 1.3 1.2 2.6 3.6 2.7 2.6 3.0 1.5 2.9 3.3 1.0 1.6 1.1 5.9 0.8 1.6 3.7 7.6 4.4 5.4 2.3 10.7 3.8 6.9 4.0 2.4 3.3 11.4 5.2 1.6 9.4 1.2 1.4 1.5 4.5 7.7 7.7 3.6 5.5 2.1 2.7 5.3 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 3.1 3.1 3.0 2.0 2.4 3.4 3.0 2.7 2.9 3.3 4.3 2.2 3.2 4.1 16.6 0.4 1.0 0.9 0.8 1.2 2.1 2.5 2.8 1.2 14.3 1.1 0.0 0.0 1.0 1.9 81.7 0.0 3.7 2.3 2.5 4.5 1.9 3.0 0.8 4.1 2.0 0.6 2.6 2.6 4.4 1.3 11.3 2.5 0.6 0.7 1.7 8.1 3.7 0.0 1.0 0.3 2.7 5.3 1.1 0.0 1.9 0.6 1.7 0.0 6.0 15.1 2.2 16.0 4.9 0.8 0.6 27.4 2.3 2.6 2.5 0.0 0.9 2.1 3.3 1.7 1.1 0.4 1.5 1.2 62.5 9.0 0.5 CLEC4E "CLECSF9, mincle" ENSG00000166523 "C-type lectin domain family 4 member E" Q9ULY5 12 8533305-8540905 "Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 75.7;lymphoid tissue: 52.3" "Cell type enhanced" "Detected in some" "Glandular and luminal cells: 31.9;Kupffer cells: 158.0;Macrophages: 115.2;monocytes: 109.5" "Cancer enhanced" "Detected in many" "testis cancer: 6.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 16 "classical monocyte: 128.8;neutrophil: 448.8" "Group enriched" "Detected in many" 17 "granulocytes: 448.8;monocytes: 128.8" "Group enriched" "Detected in some" 4 "NB-4: 4.3;RPTEC TERT1: 12.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA004935 Uncertain Uncertain Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 41: Macrophages - Immune response" Cytosol "HPA004935: AB_2667299" "unprognostic (3.05e-2)" "unprognostic (2.01e-2)" "unprognostic (8.91e-2)" "unprognostic (3.76e-1)" "unprognostic (1.76e-1)" "unprognostic (9.71e-3)" "unprognostic (1.77e-1)" "unprognostic (1.24e-1)" "unprognostic (9.29e-2)" "unprognostic (1.83e-1)" "unprognostic (1.16e-1)" "unprognostic (2.11e-2)" "unprognostic (7.65e-3)" "unprognostic (1.62e-1)" "unprognostic (1.51e-1)" "unprognostic (8.44e-2)" "unprognostic (2.29e-1)" 13.3 5.4 2.3 37.5 2.1 75.7 4.5 1.8 4.4 5.8 2.2 2.2 0.4 2.3 0.4 3.2 5.5 11.8 2.5 2.3 2.9 3.6 6.6 22.4 7.6 1.3 1.3 1.7 6.2 1.7 1.9 2.1 1.2 2.3 1.0 1.3 1.4 1.2 0.7 0.9 3.1 5.7 0.7 52.3 2.5 1.1 2.0 2.2 10.5 5.0 2.3 9.6 1.7 2.9 0.1 0.4 0.4 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.1 1.5 0.1 0.1 2.0 0.0 0.1 0.1 0.2 0.2 0.1 0.3 0.2 0.2 0.1 0.5 0.1 0.0 1.5 0.0 0.5 0.2 0.2 0.2 0.2 0.0 0.1 0.0 4.3 0.3 0.0 0.0 0.0 0.2 0.1 12.4 0.1 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.4 1.0 0.5 0.1 1.0 0.1 0.2 0.1 0.1 1.3 0.4 0.1 0.2 128.8 0.5 0.1 18.1 0.3 0.1 0.1 0.1 16.9 0.1 0.0 0.1 448.8 0.0 0.7 0.7 0.0 30.3 2.3 2.1 1.8 4.4 2.3 2.9 1.3 1.3 1.2 0.7 2.0 2.9 6.2 0.0 4.7 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 5.7 1.8 1.8 0.0 0.0 0.3 0.0 0.0 9.0 0.3 2.1 4.4 3.5 0.0 0.0 0.0 0.0 0.1 1.4 0.0 31.9 0.0 0.0 7.1 2.1 5.6 0.0 0.0 0.0 0.0 158.0 9.0 2.9 0.9 115.2 0.0 0.0 109.5 0.0 4.1 0.0 0.0 0.4 0.0 0.4 1.3 0.0 0.0 0.2 0.7 0.0 13.1 0.2 0.4 0.2 0.5 0.1 0.0 0.1 1.1 0.0 0.0 0.1 CLIC1 "CLCNL1, G6, NCC27, p64CLCP" ENSG00000213719 "Chloride intracellular channel 1" O00299 6 31730581-31739763 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020825, CAB040557" Enhanced Supported Cytosol NA NA 22000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "CAB020825: , CAB040557: " "unprognostic (7.26e-2)" "unprognostic (9.32e-2)" "unprognostic (2.78e-3)" "unprognostic (7.29e-2)" "unprognostic (6.93e-2)" "unprognostic (2.73e-2)" "prognostic unfavorable (8.90e-7)" "unprognostic (2.58e-2)" "unprognostic (8.51e-2)" "unprognostic (8.71e-3)" "unprognostic (1.19e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (8.11e-5)" "unprognostic (4.51e-2)" "unprognostic (2.89e-1)" "unprognostic (1.35e-2)" "unprognostic (7.31e-2)" 292.8 156.5 6.9 43.4 6.8 64.0 256.7 7.1 11.0 222.2 8.7 291.6 37.0 197.9 20.9 395.9 190.5 43.7 183.7 6.7 10.2 318.5 102.6 330.4 44.1 9.4 7.7 149.8 148.1 20.1 111.5 45.5 8.9 217.0 64.0 2.6 251.3 22.3 47.3 324.8 231.6 32.7 8.9 332.6 247.8 41.0 9.6 35.2 180.8 11.1 58.1 257.7 246.8 8.9 119.5 54.1 87.0 45.6 56.6 118.6 43.3 52.8 105.4 92.6 77.9 125.2 87.2 48.7 73.6 186.0 116.9 70.2 65.8 154.9 124.4 38.9 34.4 93.0 43.4 109.3 73.0 164.3 125.9 74.3 80.5 157.0 148.4 101.7 157.9 44.6 109.4 149.5 181.0 79.2 77.2 213.2 7.7 128.9 78.4 13.5 47.5 115.3 210.2 73.0 16.5 19.5 43.1 49.1 71.5 60.4 33.7 228.3 105.0 128.6 91.2 39.0 166.8 48.3 98.3 66.0 62.4 122.0 136.6 244.3 179.4 239.3 165.6 194.3 135.8 186.1 98.0 155.5 143.8 150.3 30.5 92.3 341.1 176.3 174.3 80.5 149.2 414.2 6.9 6.8 7.1 11.0 6.7 10.2 9.4 7.7 8.9 8.9 9.6 8.9 514.8 70.5 67.0 0.7 382.5 960.8 589.1 869.7 331.2 0.4 274.3 300.5 18.6 296.0 457.7 237.3 0.0 545.5 472.2 730.7 602.6 1096.2 31.8 271.1 212.7 490.1 381.4 208.6 0.0 1008.9 912.5 296.6 370.5 301.3 554.1 431.2 300.9 54.2 1047.6 0.0 0.0 665.6 516.8 533.7 1529.8 17.3 233.9 685.7 524.7 13.1 426.4 86.8 706.5 0.5 0.0 1470.4 997.1 188.1 420.2 851.1 707.7 572.1 473.6 6.9 203.8 136.1 554.0 28.7 16.2 464.1 928.0 572.7 522.2 283.3 675.0 1005.9 CLU "APOJ, CLI, CLU1, CLU2, KUB1, SGP-2, SP-40, TRPM-2" ENSG00000120885 Clusterin P10909 8 27596917-27614700 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Complement pathway, Immunity, Innate immunity" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 10230.8;liver: 9779.1" "Group enriched" "Detected in all" 4 "Cholangiocytes: 2586.5;Collecting duct cells: 3525.7;Hepatocytes: 4230.2;Muller glia cells: 8522.6" "Cancer enhanced" "Detected in all" "glioma: 1485.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "basophil: 767.1" "Lineage enriched" "Detected in all" 33 "granulocytes: 767.1" "Cell line enhanced" "Detected in all" "HeLa: 3644.3;SK-BR-3: 3500.4;T-47d: 2562.4;U-2 OS: 2225.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000572, CAB016253, HPA075983" Enhanced Supported Cytosol "Secreted to blood" NA NA 169000000000 29000000000 "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" Cytosol "CAB016253: AB_673562, HPA000572: AB_1078539, HPA075983: " "unprognostic (1.10e-2)" "unprognostic (1.81e-2)" "unprognostic (1.14e-3)" "unprognostic (2.74e-2)" "unprognostic (5.59e-2)" "unprognostic (4.13e-2)" "unprognostic (1.76e-2)" "unprognostic (2.37e-1)" "unprognostic (1.46e-1)" "unprognostic (1.05e-1)" "unprognostic (2.87e-2)" "unprognostic (1.41e-1)" "unprognostic (1.80e-2)" "unprognostic (2.33e-2)" "unprognostic (1.72e-1)" "prognostic favorable (7.66e-5)" "unprognostic (5.29e-2)" 1438.7 3809.7 6730.2 897.0 6536.5 53.2 1423.8 6992.3 8050.5 1389.4 6057.7 1407.9 323.9 1152.5 9148.8 768.6 3543.7 2863.5 617.7 6660.5 8149.9 1170.5 9779.1 827.8 2309.4 10230.8 8450.9 756.7 2246.3 1689.2 827.2 131.2 8001.8 986.4 276.1 3274.6 1453.0 5466.4 114.1 281.9 662.7 1439.9 8813.6 295.4 1081.6 2709.4 7385.0 388.1 2406.8 267.7 2343.1 1777.4 741.0 9752.3 13.0 1673.1 73.2 86.4 401.4 546.1 230.7 297.8 584.8 77.3 40.1 323.4 265.5 6.6 1159.9 267.1 926.6 561.2 318.4 48.1 50.3 1268.7 306.4 741.8 3644.3 403.7 348.8 19.2 1891.2 923.4 189.1 334.0 95.5 719.5 1028.1 10.6 10.1 842.2 27.5 288.4 5.7 56.5 603.3 505.3 197.6 6.5 276.1 236.3 763.0 1220.2 66.7 41.7 412.3 3500.4 18.1 349.1 2562.4 10.3 153.2 24.0 2225.3 131.8 101.9 108.1 419.0 16.1 1808.8 122.4 10.3 767.1 18.4 8.9 19.8 6.2 7.4 0.7 23.1 21.3 6.2 1.6 2.8 7.0 79.8 9.3 1.1 11.8 6.5 1073.6 6730.2 6536.5 6992.3 8050.5 6660.5 8149.9 10230.8 8450.9 8001.8 8813.6 7385.0 9752.3 255.3 32.1 91.8 720.5 16.1 81.3 944.6 134.1 118.9 74.3 475.3 480.4 86.1 2586.5 514.0 3525.7 77.2 116.3 15.2 23.6 41.1 488.3 311.3 196.9 31.1 442.0 9.5 92.4 73.4 620.7 22.7 614.8 226.8 185.6 803.0 31.4 1037.7 4230.2 12.6 30.3 81.0 30.9 28.5 180.5 88.9 789.3 114.3 244.6 206.3 69.3 25.1 8522.6 11.3 61.3 54.3 174.8 15.0 57.2 11.6 200.5 9.9 459.2 709.1 221.4 13.1 334.4 157.7 189.8 20.3 58.8 55.3 85.6 58.7 288.9 49.3 353.7 CNEP1R1 "C16orf69, FLJ38101, NEP1-R1, TMEM188" ENSG00000205423 "CTD nuclear envelope phosphatase 1 regulatory subunit 1" Q8N9A8 16 50024410-50037088 "Predicted membrane proteins" "Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042815, HPA077906" Uncertain Supported Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 14: REH - Unknown function" "Cluster 41: Macrophages - Immune response" Cytosol "HPA042815: AB_10794765, HPA077906: AB_2686868" "unprognostic (4.11e-2)" "unprognostic (2.45e-1)" "unprognostic (2.79e-2)" "unprognostic (1.18e-2)" "unprognostic (2.00e-2)" "unprognostic (6.33e-2)" "unprognostic (1.43e-3)" "unprognostic (1.80e-1)" "unprognostic (3.42e-2)" "unprognostic (8.53e-2)" "unprognostic (3.86e-2)" "unprognostic (1.21e-2)" "unprognostic (3.37e-3)" "unprognostic (5.09e-2)" "unprognostic (2.09e-1)" "unprognostic (3.81e-2)" "unprognostic (6.78e-2)" 9.6 8.4 6.4 14.4 7.3 23.8 7.9 8.0 7.1 8.4 5.9 9.4 8.9 9.2 12.9 12.0 7.6 10.7 9.0 6.7 6.6 7.1 10.6 9.5 14.3 6.6 5.9 9.8 7.1 8.6 8.4 15.6 6.6 8.3 13.4 9.6 8.3 8.2 10.1 11.6 9.2 11.0 6.7 13.4 9.8 18.0 6.7 9.5 5.4 7.3 15.3 10.0 9.0 7.9 11.2 10.2 12.4 13.9 23.5 23.1 17.4 22.5 17.1 21.4 12.5 11.0 15.3 12.4 16.3 18.7 14.6 17.0 10.0 10.9 27.1 9.1 11.7 6.1 6.7 17.8 16.7 8.1 18.1 17.0 18.2 13.9 10.8 16.6 14.8 15.5 7.6 6.9 27.4 3.4 16.0 21.0 9.0 4.9 13.8 19.3 16.4 12.8 15.9 7.4 9.3 11.1 21.3 8.5 9.0 10.7 7.4 10.0 19.3 20.7 15.9 19.7 8.0 11.4 11.3 14.5 12.0 8.1 17.4 16.6 21.0 16.3 16.0 29.2 15.1 9.4 12.4 11.9 17.5 8.7 12.4 14.5 51.0 12.7 36.4 6.9 13.4 14.5 6.4 7.3 8.0 7.1 6.7 6.6 6.6 5.9 6.6 6.7 6.7 7.9 8.2 3.2 7.8 8.8 10.1 10.6 3.4 6.5 5.7 5.8 5.9 3.9 11.4 8.6 6.9 7.3 4.2 17.7 10.6 7.7 3.9 5.2 4.6 5.9 8.6 8.6 4.8 7.8 13.7 5.4 25.1 9.7 8.6 6.8 12.7 5.6 10.0 6.9 14.8 6.7 13.2 3.7 2.0 20.0 20.8 3.9 5.9 18.2 16.0 6.5 15.4 12.2 12.3 8.5 12.5 5.8 6.4 7.9 7.7 4.2 5.0 5.5 4.5 10.0 6.6 9.4 8.4 26.4 18.8 5.5 9.8 14.4 13.3 5.7 5.6 3.8 CNKSR1 "CNK, CNK1, KSR" ENSG00000142675 "Connector enhancer of kinase suppressor of Ras 1" Q969H4 1 26177484-26189884 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 57.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 18.6;BEWO: 16.0;CAPAN-2: 29.1;HaCaT: 20.3;hTCEpi: 17.2;OE19: 15.9;SK-BR-3: 20.8;T-47d: 16.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA030847 Uncertain Approved Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA030847: AB_10601100" "unprognostic (2.73e-3)" "unprognostic (1.27e-1)" "unprognostic (1.10e-1)" "unprognostic (1.19e-2)" "unprognostic (5.07e-2)" "unprognostic (1.03e-1)" "unprognostic (3.15e-1)" "unprognostic (1.61e-2)" "unprognostic (5.26e-2)" "unprognostic (1.37e-1)" "unprognostic (3.68e-1)" "unprognostic (2.49e-3)" "unprognostic (1.69e-3)" "unprognostic (1.90e-2)" "unprognostic (3.27e-2)" "unprognostic (2.91e-1)" "prognostic favorable (5.91e-4)" 0.7 0.1 3.6 2.6 4.1 0.3 6.0 5.3 4.7 6.6 2.2 9.4 11.9 2.5 8.2 18.7 8.2 3.6 1.4 3.6 3.7 9.5 1.6 7.3 1.4 4.0 3.6 3.2 13.4 11.7 9.6 4.7 3.8 10.3 7.4 0.9 15.6 6.6 57.2 16.6 11.4 0.7 3.2 2.4 10.5 2.4 3.8 1.1 16.7 14.3 2.9 5.5 9.0 4.9 18.6 0.0 0.3 0.2 0.3 0.0 16.0 0.3 0.0 0.2 0.0 2.9 29.1 2.0 9.1 0.0 0.2 20.3 0.5 13.0 0.4 0.0 0.9 0.4 7.4 9.2 0.1 0.2 0.3 0.0 17.2 0.0 5.0 0.0 0.0 0.6 2.2 0.1 0.0 8.4 0.2 1.5 7.7 15.9 1.7 0.2 0.2 0.0 1.9 10.7 3.5 0.9 0.1 20.8 0.3 6.9 16.7 0.0 0.0 0.0 2.4 1.0 0.2 5.8 1.1 0.7 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.8 0.1 3.6 4.1 5.3 4.7 3.6 3.7 4.0 3.6 3.8 3.2 3.8 4.9 1.6 16.0 7.2 3.6 3.1 14.7 16.9 36.6 17.6 2.8 22.9 20.2 1.1 17.2 21.2 35.0 2.1 34.2 0.5 26.7 1.9 12.3 1.1 15.9 2.8 1.9 18.6 0.0 3.3 12.4 13.7 1.3 34.7 25.9 0.0 1.8 0.7 0.2 2.8 0.0 3.7 20.0 28.5 0.0 1.2 0.8 1.2 0.8 1.8 0.0 1.4 0.7 0.0 0.5 5.1 25.0 29.9 0.7 14.3 15.7 28.4 0.5 33.1 2.9 0.0 3.6 3.3 2.4 4.2 20.2 11.4 32.4 1.1 0.1 20.0 26.6 CNNM3 ACDP3 ENSG00000168763 "Cyclin and CBS domain divalent metal cation transport mediator 3" Q8NE01 2 96816245-96835382 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 33.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016711 Supported Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA016711: AB_1847394" "unprognostic (1.50e-2)" "unprognostic (6.96e-2)" "unprognostic (2.71e-2)" "unprognostic (3.21e-2)" "unprognostic (1.82e-1)" "unprognostic (1.23e-1)" "unprognostic (2.14e-1)" "unprognostic (1.01e-1)" "unprognostic (3.03e-1)" "unprognostic (1.59e-1)" "unprognostic (8.32e-3)" "unprognostic (3.64e-1)" "unprognostic (5.31e-3)" "unprognostic (7.35e-2)" "unprognostic (3.36e-1)" "unprognostic (1.06e-1)" "unprognostic (4.48e-2)" 7.8 8.9 8.0 6.7 10.1 7.0 7.9 15.0 9.5 8.4 8.0 10.5 17.3 8.5 5.2 5.6 10.9 9.4 5.7 7.5 7.1 7.5 20.0 9.1 9.1 9.2 9.0 10.3 26.6 21.4 8.0 10.2 8.5 8.9 8.8 13.1 12.4 9.0 45.1 8.5 14.2 5.8 6.9 9.5 12.4 11.3 8.6 11.4 8.4 6.1 7.2 8.3 7.6 12.5 10.4 9.2 8.7 13.4 10.2 5.4 24.3 6.8 5.5 6.4 6.3 25.3 16.4 11.7 23.3 5.2 7.4 11.8 12.6 8.8 4.8 11.3 29.4 15.3 12.9 28.1 8.9 14.0 11.2 4.5 11.8 8.1 7.3 8.7 7.9 9.6 14.1 19.8 2.7 13.0 12.8 17.4 11.6 15.6 11.5 15.6 11.6 14.4 11.3 12.7 26.5 17.0 8.7 14.2 8.2 13.3 13.5 10.2 3.7 5.6 16.1 9.2 9.8 17.8 18.1 8.6 3.5 13.2 6.0 1.6 0.8 3.5 2.6 0.6 1.6 1.8 1.6 2.1 0.3 2.1 1.5 1.5 3.3 1.5 1.4 1.8 2.2 0.8 8.0 10.1 15.0 9.5 7.5 7.1 9.2 9.0 8.5 6.9 8.6 12.5 4.1 9.6 4.8 9.1 5.4 1.3 2.7 1.1 0.6 17.5 4.9 5.0 15.6 8.6 3.0 0.0 8.4 5.0 8.9 4.7 0.0 5.0 7.3 5.3 4.4 3.7 4.2 5.7 5.7 4.3 2.6 4.3 5.6 12.6 0.0 11.7 6.4 17.4 2.6 33.7 9.5 7.6 4.1 3.4 0.6 1.3 2.5 1.9 3.6 4.7 2.3 6.4 6.2 18.1 19.6 2.7 1.9 4.1 6.4 7.1 8.4 1.9 2.8 13.5 13.1 5.7 4.5 5.9 6.3 2.8 1.6 1.6 6.9 11.5 8.2 3.4 CNOT1 "AD-005, CDC39, KIAA1007, NOT1, NOT1H" ENSG00000125107 "CCR4-NOT transcription complex subunit 1" A5YKK6 16 58519951-58629885 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Developmental protein, Repressor" "Autism spectrum disorder, Disease variant, Holoprosencephaly, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046577, HPA049664" Approved Supported Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA046577: AB_2679706, HPA049664: AB_2680844" "unprognostic (1.30e-2)" "unprognostic (6.86e-2)" "unprognostic (9.25e-3)" "unprognostic (1.66e-1)" "unprognostic (2.39e-2)" "unprognostic (7.11e-2)" "unprognostic (3.58e-2)" "unprognostic (2.19e-1)" "unprognostic (6.43e-2)" "unprognostic (6.99e-2)" "unprognostic (1.83e-2)" "unprognostic (6.63e-2)" "unprognostic (1.33e-3)" "unprognostic (2.31e-1)" "unprognostic (1.12e-1)" "unprognostic (5.53e-2)" "unprognostic (1.52e-1)" 29.8 35.2 8.4 46.9 10.7 45.6 36.3 17.4 11.5 34.7 33.5 60.1 55.0 31.8 27.6 73.1 38.9 28.3 26.3 8.6 9.4 39.8 36.0 33.3 58.1 11.5 10.5 39.2 41.1 59.7 21.2 35.1 11.3 31.2 57.3 32.4 38.8 30.6 52.4 43.1 52.3 33.7 8.9 42.9 42.1 108.2 10.6 76.4 42.4 44.1 69.5 49.1 38.6 15.2 128.8 148.2 110.0 88.1 52.1 66.2 127.6 99.6 85.8 111.4 82.0 167.6 75.3 194.0 47.4 75.8 65.5 122.3 177.9 101.0 149.2 72.5 98.8 150.4 121.8 193.7 70.8 235.8 162.4 64.0 67.5 129.7 151.5 66.9 87.7 107.2 181.0 55.3 76.4 52.0 182.6 61.2 114.4 84.9 127.2 229.0 189.5 122.7 62.4 180.0 90.9 58.6 336.0 113.5 56.0 100.5 67.9 121.3 100.9 81.3 80.0 62.2 88.7 124.7 138.2 390.3 85.5 99.4 76.9 18.3 12.1 13.4 13.8 15.6 18.2 14.7 12.9 14.0 14.6 13.8 12.1 12.6 18.6 15.4 22.5 7.3 15.4 11.5 8.4 10.7 17.4 11.5 8.6 9.4 11.5 10.5 11.3 8.9 10.6 15.2 44.4 16.0 42.9 33.0 57.8 47.4 32.6 42.9 25.6 28.2 33.9 27.9 23.8 37.1 45.2 23.9 29.2 33.7 86.3 64.5 9.8 29.8 107.7 57.6 48.0 31.3 36.1 45.0 31.7 47.0 29.9 30.7 35.2 78.2 32.2 45.9 23.9 42.3 35.7 40.4 35.6 54.2 24.4 51.5 39.5 38.6 24.8 46.4 19.6 42.2 50.0 20.0 34.0 42.3 54.9 42.5 34.9 32.4 59.8 43.6 60.1 22.9 51.6 24.3 32.9 38.7 30.4 136.6 64.3 56.0 47.0 37.9 52.1 27.9 64.5 61.2 CNOT3 "KIAA0691, LENG2, NOT3, NOT3H" ENSG00000088038 "CCR4-NOT transcription complex subunit 3" O75175 19 54137749-54155681 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Developmental protein, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEK 293: 213.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006408 Approved Approved Cytosol NA NA 39000 "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA006408: AB_1078543" "unprognostic (1.23e-1)" "unprognostic (2.54e-1)" "unprognostic (1.75e-2)" "unprognostic (1.40e-1)" "unprognostic (4.86e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (2.22e-4)" "unprognostic (9.06e-2)" "unprognostic (1.43e-2)" "unprognostic (2.65e-2)" "unprognostic (9.30e-3)" "unprognostic (4.08e-3)" "prognostic unfavorable (2.77e-4)" "unprognostic (2.18e-1)" "unprognostic (1.73e-1)" "unprognostic (2.11e-1)" "unprognostic (2.66e-2)" 21.3 29.0 11.3 17.5 11.6 19.6 22.9 13.7 14.1 27.0 7.6 27.1 16.8 27.3 19.6 26.8 27.5 12.5 19.4 10.9 14.2 24.8 25.3 21.2 20.4 12.0 9.5 30.5 28.3 17.5 34.0 19.2 10.4 27.6 13.2 18.0 26.1 18.7 24.1 30.3 25.1 16.8 7.1 29.9 26.6 35.2 10.8 23.6 30.0 11.0 18.1 25.6 25.5 12.0 45.5 69.1 69.7 40.8 25.4 25.2 48.0 39.2 68.4 52.2 45.9 44.2 36.2 53.1 24.8 46.1 41.8 44.1 77.3 39.2 53.1 55.5 213.4 81.7 44.5 39.1 43.3 47.7 54.9 32.1 35.8 46.7 77.3 37.1 41.5 39.0 61.8 47.9 38.3 53.3 63.8 27.9 43.1 87.7 52.4 57.8 52.4 35.7 33.7 85.4 44.9 37.2 75.1 54.6 25.8 50.6 31.3 50.2 37.8 47.3 50.3 23.4 54.4 46.3 54.1 71.2 38.7 37.1 48.0 0.9 1.6 3.1 1.6 1.0 1.2 1.3 1.1 1.5 1.4 1.4 1.2 1.3 4.2 0.8 1.4 3.4 1.2 2.0 11.3 11.6 13.7 14.1 10.9 14.2 12.0 9.5 10.4 7.1 10.8 12.0 14.2 12.8 7.4 10.7 17.4 9.9 17.2 15.7 18.8 17.5 14.0 13.8 2.0 12.8 14.4 7.3 16.7 28.8 20.5 17.8 9.8 14.8 19.9 20.9 19.6 13.2 14.4 13.3 6.1 14.5 28.5 13.6 20.9 21.4 3.8 22.7 12.5 8.5 16.2 16.8 7.0 17.1 18.3 9.7 6.9 6.6 17.1 13.1 5.4 4.7 15.6 12.0 16.5 5.0 8.0 15.1 23.9 9.4 20.8 21.4 14.9 9.0 14.3 18.5 6.6 17.3 17.9 49.2 47.9 16.6 9.9 50.1 15.4 21.6 13.2 17.3 CNOT6 "CCR4, Ccr4a, KIAA1194" ENSG00000113300 "CCR4-NOT transcription complex subunit 6" Q9ULM6 5 180494379-180578358 "Enzymes, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Activator, Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044568 Approved Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 52: Non-specific - Transcription" Cytosol "HPA044568: AB_10797257" "unprognostic (9.41e-3)" "unprognostic (1.40e-1)" "unprognostic (2.03e-3)" "unprognostic (2.55e-1)" "unprognostic (1.41e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (3.61e-7)" "unprognostic (1.31e-1)" "unprognostic (1.10e-2)" "unprognostic (1.85e-2)" "unprognostic (2.50e-2)" "unprognostic (2.35e-2)" "unprognostic (1.79e-2)" "unprognostic (1.25e-1)" "unprognostic (1.26e-1)" "unprognostic (4.03e-2)" "unprognostic (3.57e-2)" 6.6 6.5 8.7 12.0 9.1 11.9 9.5 16.1 8.8 8.0 10.1 10.0 12.1 9.2 8.6 11.5 9.4 7.3 6.2 7.9 9.3 10.0 5.1 9.7 11.4 8.9 8.7 9.4 6.6 8.7 5.6 11.8 7.9 9.4 11.5 17.5 7.1 7.4 5.2 9.3 11.9 8.1 8.4 10.0 10.1 13.5 9.2 19.7 9.0 7.4 14.0 11.4 8.0 9.4 24.9 29.6 59.2 47.5 9.6 10.9 61.0 17.9 12.0 23.2 27.5 36.1 35.7 26.2 26.5 11.8 32.2 25.5 50.0 59.4 27.1 77.5 25.2 28.6 38.4 23.4 14.3 33.6 20.1 9.3 28.1 17.1 36.1 21.6 28.6 30.2 30.9 24.5 21.8 51.1 43.0 20.2 17.5 25.0 13.9 39.1 29.6 18.6 25.6 48.5 43.0 36.4 30.1 39.7 26.2 28.7 49.9 33.5 31.4 24.5 28.1 18.0 32.0 16.0 30.9 27.4 23.4 45.3 20.6 0.7 0.8 1.2 1.2 1.4 1.3 0.6 1.0 0.7 0.8 0.7 1.4 1.4 0.8 0.7 2.3 0.8 0.8 0.6 8.7 9.1 16.1 8.8 7.9 9.3 8.9 8.7 7.9 8.4 9.2 9.4 12.4 28.9 13.4 16.3 11.9 21.7 6.4 12.9 15.9 18.0 19.5 11.7 11.4 14.3 12.4 11.0 22.9 9.4 21.9 17.1 1.9 11.0 6.4 32.3 22.3 13.2 14.5 27.8 27.2 9.3 12.8 11.8 11.2 21.1 2.5 29.7 13.6 5.7 12.5 18.5 24.9 13.8 6.1 16.2 15.4 9.3 13.1 14.4 10.6 18.7 20.1 13.5 26.8 30.2 33.4 17.6 8.4 18.8 15.5 17.3 12.1 13.1 20.2 17.5 26.3 11.7 13.1 38.6 48.7 23.2 22.3 11.5 16.2 12.8 16.5 19.9 CNOT6L "Ccr4b, DKFZp434K098" ENSG00000138767 "CCR4-NOT transcription complex subunit 6 like" Q96LI5 4 77713387-77819615 "Enzymes, Predicted intracellular proteins" "mRNA processing, RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 366.6;T-cells: 240.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042688 Uncertain Supported Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA042688: AB_10794384" "unprognostic (3.91e-1)" "unprognostic (1.95e-2)" "unprognostic (7.91e-3)" "unprognostic (4.10e-2)" "unprognostic (2.56e-1)" "unprognostic (3.72e-2)" "unprognostic (8.79e-2)" "unprognostic (1.09e-1)" "unprognostic (5.06e-2)" "unprognostic (6.86e-2)" "unprognostic (3.55e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.69e-4)" "unprognostic (4.51e-2)" "unprognostic (7.95e-2)" "unprognostic (1.06e-1)" "unprognostic (1.91e-3)" 11.8 9.5 6.9 22.4 7.7 29.5 13.4 14.4 8.1 12.4 6.1 12.9 13.1 11.1 9.8 16.6 11.6 14.0 6.1 6.4 10.1 13.2 19.6 11.6 36.1 7.5 7.7 13.6 19.9 17.8 6.0 22.5 7.1 11.7 15.5 12.9 12.6 12.2 7.2 13.7 13.6 14.5 8.2 23.6 14.7 11.2 11.5 49.5 14.4 8.6 38.5 15.7 8.4 9.0 17.0 9.6 12.5 9.1 14.7 13.6 13.1 13.1 17.8 11.9 15.9 3.5 18.3 26.5 15.4 18.9 8.6 10.9 17.5 18.7 14.9 28.4 10.0 25.4 9.8 10.3 9.1 24.0 22.9 8.1 22.7 12.1 24.3 10.9 38.2 21.2 22.7 38.0 13.9 9.0 52.3 14.0 6.2 13.4 3.2 12.4 38.4 21.5 12.5 13.5 16.0 7.2 23.3 20.1 7.9 15.4 6.8 13.7 35.6 10.9 11.5 19.9 7.3 48.1 21.0 35.1 12.3 11.9 8.6 21.4 4.4 10.6 9.4 7.0 9.9 5.5 7.2 7.7 4.4 7.2 6.7 8.2 6.9 8.2 10.3 6.4 6.4 4.1 6.9 7.7 14.4 8.1 6.4 10.1 7.5 7.7 7.1 8.2 11.5 9.0 93.0 22.4 21.0 34.3 101.1 57.9 13.3 15.9 59.2 39.5 30.5 20.8 16.7 31.5 24.0 36.8 39.6 31.1 366.6 16.9 60.7 8.2 4.7 30.1 24.6 54.0 26.3 31.5 74.8 12.4 8.6 25.1 26.5 46.2 38.0 22.1 45.3 32.6 17.1 32.0 70.7 29.8 14.2 41.0 50.1 3.7 18.6 50.0 24.9 105.9 39.2 19.3 128.8 68.9 60.7 11.0 16.1 12.8 178.5 33.9 28.4 26.3 17.0 43.5 32.9 26.6 29.2 49.4 39.9 44.7 66.1 24.4 240.0 37.9 24.1 26.7 CNPY2 "HP10390, TMEM4, ZSIG9" ENSG00000257727 "Canopy FGF signaling regulator 2" Q9Y2B0 12 56309842-56316119 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 475.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA038465, HPA038466" Supported Supported Cytosol "Intracellular and membrane" NA NA 220000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "HPA038465: AB_10967609, HPA038466: AB_10672646" "unprognostic (3.83e-2)" "unprognostic (5.62e-2)" "unprognostic (2.49e-1)" "unprognostic (2.46e-2)" "unprognostic (4.33e-2)" "unprognostic (2.20e-1)" "unprognostic (1.17e-3)" "unprognostic (1.46e-1)" "unprognostic (7.68e-2)" "unprognostic (2.04e-3)" "prognostic favorable (8.37e-4)" "unprognostic (5.89e-2)" "prognostic unfavorable (2.32e-8)" "unprognostic (1.91e-1)" "unprognostic (1.16e-1)" "unprognostic (2.67e-2)" "unprognostic (5.06e-2)" 36.7 52.5 28.4 25.8 30.3 24.7 41.8 30.0 30.7 43.3 38.1 36.6 30.9 35.6 74.4 34.1 38.1 25.4 28.4 27.7 31.8 37.8 75.7 30.5 22.0 31.1 29.0 42.7 58.9 47.3 66.8 40.8 28.9 35.3 38.5 18.8 53.1 36.4 21.2 23.5 34.6 24.9 30.5 35.1 42.1 20.0 29.8 27.0 44.7 18.6 26.6 32.9 31.1 32.2 50.6 75.5 76.0 62.8 186.0 64.0 120.7 51.0 117.4 108.7 76.5 116.0 87.9 51.2 95.0 132.4 53.2 72.4 92.3 62.8 68.7 51.3 57.5 49.9 106.1 121.8 83.6 94.9 60.4 76.5 80.5 89.9 106.6 165.5 91.1 59.0 73.8 113.5 81.3 76.2 58.2 105.3 72.6 107.5 109.5 65.1 58.3 84.9 90.1 47.6 67.9 41.7 85.1 86.8 93.6 92.7 78.0 176.8 41.2 42.7 33.6 52.2 74.7 58.4 88.2 41.5 90.2 88.2 70.9 56.8 66.5 36.8 65.8 56.9 77.8 73.2 70.7 71.7 69.5 66.2 70.4 67.0 9.8 70.9 34.6 71.3 68.4 76.4 28.4 30.3 30.0 30.7 27.7 31.8 31.1 29.0 28.9 30.5 29.8 32.2 76.2 48.1 93.7 17.3 79.2 54.8 75.2 129.9 17.1 80.5 178.6 191.6 9.8 140.2 95.2 101.2 64.6 248.3 74.0 80.2 52.8 191.8 40.2 54.7 59.9 72.6 141.9 34.3 31.8 168.7 475.0 77.5 31.1 53.1 91.3 60.7 98.9 185.8 147.4 58.9 32.4 187.2 103.7 59.2 55.8 17.7 103.8 47.8 122.7 13.1 99.7 88.6 125.7 40.2 45.6 162.4 114.1 100.1 68.2 107.4 176.6 145.5 74.1 92.2 26.3 59.1 82.8 72.4 44.0 20.0 53.8 236.4 60.5 78.2 177.8 71.0 CNRIP1 "C2orf32, CRIP1, CRIP1a, CRIP1b, DKFZP566K1924" ENSG00000119865 "Cannabinoid receptor interacting protein 1" Q96F85 2 68284171-68320051 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 71.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 72.2;Erythroid cells: 116.2;granulocytes: 122.9" "Cancer enhanced" "Detected in all" "glioma: 14.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 109 "basophil: 12.2" "Lineage enriched" "Detected in single" 109 "granulocytes: 12.2" "Cell line enhanced" "Detected in many" "HEL: 158.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035337 Approved Cytosol NA NA 54000 "Cluster 38: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA035337: AB_10601359" "unprognostic (1.23e-1)" "unprognostic (8.88e-2)" "unprognostic (1.32e-1)" "unprognostic (2.85e-1)" "unprognostic (1.31e-1)" "unprognostic (1.20e-1)" "unprognostic (6.51e-2)" "unprognostic (3.52e-2)" "unprognostic (2.86e-2)" "unprognostic (4.58e-2)" "unprognostic (4.71e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.04e-2)" "unprognostic (3.63e-2)" "unprognostic (1.69e-1)" "unprognostic (3.38e-3)" 27.4 6.4 59.0 5.9 62.3 6.1 20.2 50.9 71.6 30.1 29.6 17.1 3.5 22.4 6.1 5.3 24.2 8.5 16.0 65.1 51.8 10.3 2.9 18.3 5.1 40.4 45.1 31.2 3.0 1.8 15.4 12.1 44.3 15.1 4.6 29.6 5.8 8.9 6.6 8.1 10.9 9.3 44.7 10.2 10.6 2.6 52.7 2.7 8.9 7.0 2.9 20.7 19.2 51.8 0.0 1.1 9.0 0.0 34.1 24.6 0.1 34.5 26.6 30.6 22.3 0.0 0.0 0.0 1.2 33.2 22.6 0.0 0.7 0.2 32.6 0.0 8.1 158.7 2.3 0.0 34.7 0.1 21.7 22.1 0.0 20.0 11.5 18.7 47.8 0.0 0.2 0.1 23.4 0.1 0.0 0.4 16.3 0.0 15.6 0.0 13.2 0.0 0.0 0.0 45.8 47.8 2.2 0.0 28.3 0.1 0.0 1.7 51.4 21.1 12.9 18.5 51.0 0.0 0.0 0.1 16.9 0.0 15.5 12.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 59.0 62.3 50.9 71.6 65.1 51.8 40.4 45.1 44.3 44.7 52.7 51.8 50.2 0.0 4.3 15.0 0.6 12.9 0.4 0.0 4.6 72.2 0.6 1.7 2.1 0.0 0.6 0.0 22.9 1.2 0.1 0.0 0.0 0.4 0.7 1.9 30.4 60.6 0.0 116.2 48.8 0.2 9.3 44.4 0.5 0.6 122.9 1.3 36.4 0.8 56.3 28.6 39.5 0.0 0.0 25.7 40.9 2.6 45.4 13.9 37.4 16.9 2.5 42.0 0.0 24.1 19.6 0.5 0.0 42.5 0.5 1.2 0.0 0.1 0.0 54.3 46.0 18.7 41.9 0.7 0.5 0.7 10.7 2.1 3.8 27.3 0.0 1.0 COL21A1 ENSG00000124749 "Collagen type XXI alpha 1 chain" Q96P44 6 56056590-56394094 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 24.1;placenta: 28.3" "Cell type enhanced" "Detected in many" "Astrocytes: 66.6;Cardiomyocytes: 36.9;Extravillous trophoblasts: 75.3;Inhibitory neurons: 63.3;Respiratory ciliated cells: 51.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ASC TERT1: 23.4;BEWO: 7.6;HSkMC: 24.0;SuSa: 11.1" "Low region specificity" "Detected in all" HPA031212 Supported Cytosol "Secreted to extracellular matrix" NA NA 290000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "HPA031212: AB_10599941" "unprognostic (1.69e-1)" "unprognostic (4.53e-2)" "unprognostic (1.58e-1)" "unprognostic (2.56e-1)" "unprognostic (1.21e-1)" "unprognostic (9.32e-3)" "unprognostic (6.84e-2)" "unprognostic (9.04e-3)" "unprognostic (1.54e-3)" "unprognostic (2.17e-1)" "unprognostic (5.29e-2)" "unprognostic (3.10e-1)" "unprognostic (1.26e-3)" "unprognostic (3.27e-2)" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (1.27e-3)" 2.6 1.4 2.6 0.6 3.2 0.0 1.4 3.3 1.9 24.1 11.4 7.8 0.5 12.4 2.8 2.4 7.4 3.8 4.2 2.4 5.6 1.1 1.2 7.6 0.5 2.7 6.3 3.7 1.9 0.6 1.9 28.3 3.1 3.5 2.0 0.0 5.0 10.7 1.3 6.6 1.3 7.9 1.5 0.5 2.7 2.7 4.0 0.7 1.0 6.6 0.5 6.1 6.0 2.7 0.0 3.4 0.2 0.0 1.3 23.4 7.6 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 3.2 0.1 0.0 24.0 0.9 0.0 0.3 0.5 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 11.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.2 3.3 1.9 2.4 5.6 2.7 6.3 3.1 1.5 4.0 2.7 6.4 0.0 1.5 66.6 0.0 5.9 2.2 2.8 2.2 0.0 0.3 0.4 36.9 0.0 8.2 0.0 0.0 27.5 0.1 0.0 0.0 0.0 7.4 24.8 10.6 6.6 0.0 0.0 16.0 0.0 75.3 28.2 0.5 1.2 0.0 0.2 2.9 0.0 6.1 0.0 63.3 0.0 16.2 0.3 3.0 1.7 15.2 0.3 5.4 0.0 0.0 0.0 0.0 3.5 1.6 0.0 0.0 12.4 0.0 0.1 0.1 0.1 51.3 0.0 0.0 7.3 15.0 1.2 2.5 1.0 4.1 23.3 0.4 2.1 0.2 1.3 COL6A1 ENSG00000142156 "Collagen type VI alpha 1 chain" P12109 21 45981769-46005050 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Congenital muscular dystrophy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 796.8" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 578.3;Fibroblasts: 816.1;Leydig cells: 353.0;Peritubular cells: 251.3;Smooth muscle cells: 324.4;Theca cells: 246.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1157.2;ASC TERT1: 2331.5;BJ: 927.1;HHSteC: 1025.3;HSkMC: 1711.4;U-138 MG: 1297.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 46.8" "HPA019142, HPA029401" Enhanced Approved Cytosol "Secreted to extracellular matrix" NA NA 250000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "HPA019142: AB_1847093, HPA029401: AB_10601361" "unprognostic (3.45e-1)" "unprognostic (4.09e-2)" "unprognostic (8.71e-2)" "unprognostic (1.72e-1)" "unprognostic (5.79e-3)" "unprognostic (2.12e-1)" "unprognostic (6.27e-2)" "unprognostic (1.09e-2)" "unprognostic (4.47e-2)" "unprognostic (3.69e-2)" "unprognostic (6.06e-3)" "unprognostic (3.86e-1)" "prognostic unfavorable (1.07e-8)" "unprognostic (5.16e-2)" "unprognostic (7.39e-2)" "unprognostic (3.53e-3)" "prognostic unfavorable (4.54e-4)" 285.9 50.1 15.7 153.3 9.0 0.7 173.9 33.9 20.4 499.3 32.1 796.8 73.3 556.3 24.6 91.1 411.5 194.4 155.6 10.3 14.9 66.1 48.3 140.3 37.5 23.1 18.4 491.4 57.8 29.1 117.8 287.1 21.5 246.8 40.5 3.4 97.7 142.3 85.4 123.4 217.7 177.9 11.3 70.7 230.5 32.8 14.9 30.7 92.6 39.5 16.6 478.7 284.7 9.7 2.9 20.2 31.2 99.6 1157.2 2331.5 3.9 927.1 586.3 231.7 80.7 16.2 62.8 0.1 75.1 522.2 183.6 4.3 13.5 2.3 19.5 0.5 14.9 0.0 3.7 5.2 1025.3 0.3 2.2 1711.4 1.0 578.6 7.8 20.9 5.6 0.2 0.7 0.6 60.9 1.4 0.3 3.2 22.4 13.4 263.2 0.1 19.5 4.3 1.6 11.1 1.0 39.9 87.6 1.1 17.9 10.4 4.2 4.2 0.5 1297.6 86.7 362.7 358.1 0.6 0.4 0.4 464.1 6.9 116.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 9.0 33.9 20.4 10.3 14.9 23.1 18.4 21.5 11.3 14.9 9.7 74.6 0.0 5.8 26.1 2.5 122.2 11.0 1.5 18.2 18.9 9.2 35.9 42.7 5.7 4.4 9.2 0.0 11.6 2.3 0.6 3.9 23.2 4.6 20.9 578.3 50.6 1.8 0.0 27.1 3.3 18.6 816.1 6.1 16.1 1.3 48.7 101.0 13.4 22.4 15.2 8.2 0.3 0.0 3.3 134.7 18.6 353.0 7.8 147.7 40.3 2.0 18.7 0.0 30.7 2.4 6.1 2.6 251.3 3.5 6.3 2.1 10.3 1.0 4.3 184.1 152.3 324.4 2.6 6.2 5.5 89.9 20.8 13.7 246.5 1.4 3.8 COQ10B FLJ13448 ENSG00000115520 "Coenzyme Q10B" Q9H8M1 2 197453423-197475308 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046057 Approved Approved Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: U-2197 - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "HPA046057: AB_2679518" "unprognostic (9.17e-2)" "unprognostic (1.31e-1)" "unprognostic (1.01e-2)" "unprognostic (1.82e-3)" "unprognostic (8.28e-3)" "unprognostic (5.76e-3)" "unprognostic (4.55e-1)" "unprognostic (2.93e-1)" "unprognostic (7.18e-2)" "unprognostic (6.00e-2)" "unprognostic (4.13e-2)" "unprognostic (3.99e-1)" "unprognostic (2.87e-3)" "unprognostic (1.64e-1)" "unprognostic (1.03e-1)" "unprognostic (1.94e-1)" "unprognostic (3.13e-3)" 25.0 37.7 15.2 17.4 15.4 46.8 19.1 16.2 19.0 15.7 18.6 19.7 16.2 16.5 15.9 18.8 13.0 26.1 34.3 16.2 17.1 28.6 35.1 17.6 19.8 16.3 16.5 10.5 15.9 29.6 14.3 21.6 16.8 17.5 20.3 18.3 12.7 17.6 12.8 12.7 15.4 24.9 16.7 18.8 18.3 10.7 17.3 17.3 21.1 19.1 19.4 31.0 12.2 17.9 15.7 14.7 10.5 18.8 49.6 35.3 24.6 40.2 57.5 42.3 46.8 30.0 18.5 14.7 33.4 32.5 52.5 14.1 15.3 21.3 47.8 29.0 13.2 21.0 19.1 35.4 41.5 17.0 46.6 39.5 32.8 40.3 28.5 22.9 23.3 20.9 17.9 38.1 40.9 20.4 18.6 26.4 16.2 18.4 30.0 13.9 15.7 19.4 45.7 42.0 6.8 13.1 18.4 23.9 52.0 37.2 17.1 23.9 24.6 41.4 14.4 46.8 29.3 36.0 55.0 16.5 51.7 16.3 32.7 70.8 30.0 57.5 43.7 35.5 49.2 32.8 41.4 43.6 26.4 25.2 43.0 44.4 90.7 34.1 42.8 16.7 56.5 38.0 15.2 15.4 16.2 19.0 16.2 17.1 16.3 16.5 16.8 16.7 17.3 17.9 73.2 19.2 19.9 7.2 54.4 105.5 106.5 55.7 44.9 30.2 42.3 24.3 29.0 24.3 42.3 40.5 41.7 32.7 62.5 43.7 129.1 44.9 38.7 35.8 34.5 48.9 26.9 38.3 12.4 46.1 43.7 67.6 33.1 43.5 60.3 12.2 22.9 36.7 32.0 63.9 11.8 44.3 57.0 23.8 74.6 20.7 20.5 44.3 71.2 7.5 29.2 56.7 49.4 7.1 16.0 54.2 36.3 30.5 45.1 65.6 30.0 73.7 41.7 36.6 46.0 60.8 71.0 20.9 39.4 29.0 106.6 173.9 70.9 33.7 19.1 100.0 COQ2 "CL640, FLJ26072" ENSG00000173085 "Coenzyme Q2, polyprenyltransferase" Q96H96 4 83261536-83284914 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Isoprene biosynthesis, Ubiquinone biosynthesis" Transferase "Disease variant, Neurodegeneration, Parkinsonism, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 37.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 50.7;Kupffer cells: 53.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056599, HPA068727" Approved Approved Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA056599: AB_2683184, HPA068727: AB_2686022" "unprognostic (8.26e-2)" "unprognostic (7.40e-3)" "unprognostic (3.95e-3)" "unprognostic (1.55e-1)" "unprognostic (9.22e-2)" "unprognostic (5.59e-2)" "unprognostic (1.26e-2)" "unprognostic (1.52e-1)" "unprognostic (4.09e-1)" "unprognostic (4.16e-2)" "unprognostic (2.08e-2)" "unprognostic (2.77e-3)" "unprognostic (1.56e-2)" "unprognostic (3.73e-1)" "unprognostic (1.40e-1)" "unprognostic (7.82e-2)" "unprognostic (2.46e-1)" 6.0 17.0 2.8 8.0 3.2 11.8 5.8 3.5 3.3 7.9 3.6 14.2 9.5 6.3 7.5 10.4 4.4 4.3 15.0 3.0 3.5 5.6 13.6 7.9 6.4 3.6 3.5 6.5 6.5 6.0 4.0 8.4 3.8 6.6 14.2 4.0 7.8 5.0 29.1 10.8 9.1 6.9 4.1 10.1 5.5 3.5 3.9 3.6 5.7 37.5 7.1 7.9 6.5 4.9 26.1 14.7 14.1 27.4 10.5 11.9 9.7 16.1 27.0 29.7 34.4 10.5 38.7 17.2 11.7 28.4 24.6 18.6 23.9 26.0 38.7 17.2 14.8 15.3 22.3 15.4 11.7 31.3 73.5 15.9 16.3 14.2 24.8 8.9 30.7 9.7 10.0 21.4 29.3 27.4 8.6 21.7 10.9 30.6 19.9 14.1 11.4 22.1 45.4 13.8 10.3 6.3 19.0 24.5 9.2 6.7 15.4 18.8 21.0 14.6 14.6 11.1 23.4 5.7 5.2 10.2 29.5 36.8 20.2 2.1 28.8 4.0 2.7 26.8 1.9 6.2 3.0 2.5 21.1 6.9 2.1 3.2 9.8 6.7 33.5 11.2 4.1 13.6 2.8 3.2 3.5 3.3 3.0 3.5 3.6 3.5 3.8 4.1 3.9 4.9 5.4 0.0 4.2 15.7 11.5 6.6 12.4 9.8 4.6 5.9 6.3 5.6 19.5 2.8 10.7 9.2 0.0 25.4 7.1 14.0 31.3 6.7 0.8 7.6 19.5 6.1 4.8 14.1 12.8 10.8 30.0 9.0 6.6 9.2 0.0 17.2 9.3 15.0 50.7 1.7 20.1 15.3 8.2 53.2 7.9 0.8 3.7 25.2 7.2 33.7 21.8 12.6 6.2 25.6 15.6 5.4 15.4 4.9 4.3 12.6 11.0 9.9 6.2 4.8 0.0 7.3 9.7 18.1 19.7 16.7 12.6 12.4 9.6 35.5 26.7 12.9 CORO1A "coronin-1, HCORO1, p57" ENSG00000102879 "Coronin 1A" P31146 16 30182827-30189076 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 568.8;lymphoid tissue: 583.8" "Cell type enhanced" "Detected in many" "B-cells: 523.9;dendritic cells: 588.7;Hofbauer cells: 494.4;Kupffer cells: 395.8;Macrophages: 342.7;monocytes: 583.7;NK-cells: 968.1;T-cells: 663.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 924.0;HL-60: 645.7;HMC-1: 1086.7;JURKAT: 603.0;MOLT-4: 632.5;NB-4: 771.8;RPMI-8226: 980.9;U-698: 618.2;U-937: 829.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046473, HPA051132" Enhanced Approved Cytosol NA NA 45000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "CAB046473: AB_10602363, HPA051132: AB_2681355" "unprognostic (4.17e-3)" "unprognostic (3.64e-3)" "unprognostic (3.86e-2)" "prognostic favorable (6.91e-4)" "unprognostic (2.41e-1)" "prognostic favorable (4.42e-4)" "unprognostic (1.99e-2)" "unprognostic (8.27e-3)" "unprognostic (8.26e-3)" "unprognostic (4.30e-1)" "unprognostic (1.54e-1)" "unprognostic (2.25e-1)" "prognostic unfavorable (5.74e-7)" "unprognostic (2.55e-1)" "unprognostic (2.37e-2)" "unprognostic (7.16e-2)" "unprognostic (2.01e-1)" 29.1 20.8 34.4 306.4 37.1 568.8 11.2 24.9 52.0 10.6 23.6 26.8 44.3 10.0 3.1 22.5 17.9 45.0 11.3 36.9 31.9 11.5 13.1 49.5 583.8 37.6 32.0 6.4 8.4 4.3 9.3 18.4 32.2 11.4 15.3 0.9 32.9 7.3 6.7 17.6 111.0 22.2 35.8 321.4 49.0 4.8 33.9 257.6 12.7 8.8 309.1 57.6 10.4 50.0 3.1 3.6 10.9 21.5 0.1 0.1 6.1 2.6 0.7 5.4 3.0 0.7 6.9 924.0 6.1 0.9 1.5 4.4 5.2 10.8 1.3 302.3 2.5 97.9 0.5 15.0 1.7 645.7 1086.7 2.8 0.0 4.3 0.5 0.4 2.0 603.0 1.5 467.6 3.4 80.7 632.5 771.8 4.0 3.1 6.4 340.0 17.5 980.9 1.3 5.1 17.3 13.0 2.2 110.7 2.0 0.2 1.9 373.0 1.6 4.0 9.0 2.7 3.1 348.5 497.7 618.2 3.0 829.6 6.3 797.2 773.6 2671.1 637.5 859.7 597.8 505.5 567.3 625.6 843.2 512.0 537.1 566.2 1318.9 531.0 898.0 482.1 858.7 1647.2 34.4 37.1 24.9 52.0 36.9 31.9 37.6 32.0 32.2 35.8 33.9 50.0 6.3 22.4 32.5 0.3 523.9 11.3 1.2 3.2 2.2 1.2 4.7 5.5 1.5 17.2 6.0 1.8 0.0 4.6 588.7 2.3 0.0 3.5 0.5 1.1 2.0 12.3 6.0 60.2 3.3 0.9 17.4 9.5 18.8 1.3 83.7 0.6 21.8 4.8 494.4 0.0 1.7 2.2 6.1 395.8 197.9 1.2 0.6 342.7 32.0 4.7 583.7 0.8 968.1 1.5 0.4 11.1 47.5 0.0 201.4 0.8 1.0 4.8 3.5 0.9 6.6 2.9 5.1 0.1 0.9 2.4 9.1 4.9 663.0 2.7 3.3 0.9 COTL1 CLP ENSG00000103187 "Coactosin like F-actin binding protein 1" Q14019 16 84565596-84618078 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Chaperone" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 273.2;lymphoid tissue: 374.3" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 1402.6;Hofbauer cells: 595.3;Kupffer cells: 1015.5;Langerhans cells: 1146.3;Macrophages: 1046.2;monocytes: 949.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 2441.1;eosinophil: 3418.8;intermediate monocyte: 4072.1;myeloid DC: 2395.7;neutrophil: 1758.0;non-classical monocyte: 4579.3" "Group enriched" "Detected in all" 5 "dendritic cells: 2395.7;granulocytes: 3418.8;monocytes: 4579.3" "Cell line enhanced" "Detected in all" "WM-115: 1271.3" "Low region specificity" "Detected in all" "HPA008918, CAB062328" Enhanced Supported Cytosol NA NA 10000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 17: WM-115 - Nervous system development" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "CAB062328: AB_2084785, HPA008918: AB_2668176" "unprognostic (2.93e-2)" "unprognostic (1.11e-1)" "unprognostic (3.27e-2)" "unprognostic (2.38e-1)" "unprognostic (3.21e-3)" "unprognostic (8.95e-2)" "unprognostic (2.43e-1)" "unprognostic (1.14e-1)" "unprognostic (7.70e-2)" "unprognostic (5.99e-2)" "unprognostic (5.43e-3)" "unprognostic (1.47e-2)" "prognostic unfavorable (5.51e-4)" "unprognostic (1.26e-1)" "unprognostic (5.48e-2)" "unprognostic (7.73e-2)" "unprognostic (3.35e-3)" 87.8 36.8 65.8 296.0 82.1 273.2 54.2 80.6 67.4 31.7 57.7 68.7 90.4 46.7 12.1 32.4 49.5 75.2 25.1 68.8 82.8 140.5 44.6 110.6 374.3 87.5 80.5 24.1 30.3 32.4 47.4 78.0 86.6 44.5 66.0 44.4 24.9 28.5 10.9 20.4 104.8 66.6 78.0 330.5 126.5 20.5 101.5 88.6 38.0 12.2 263.5 118.4 28.3 86.4 546.3 445.0 994.2 1058.1 111.5 305.0 299.5 462.0 295.8 355.8 136.6 609.1 818.7 149.6 137.6 349.7 211.7 266.8 61.3 364.1 355.1 1.1 77.9 281.9 87.7 162.7 314.0 320.1 1069.3 245.6 57.6 344.2 305.0 222.2 172.2 326.4 26.5 60.5 215.3 88.3 99.1 191.7 123.1 178.5 448.8 10.4 33.7 9.3 529.2 227.5 156.7 7.9 430.7 101.9 238.8 116.9 77.1 256.7 445.9 509.0 290.2 165.8 341.4 11.5 58.1 123.7 397.7 154.1 1271.3 740.1 2441.1 3418.8 69.9 4072.1 92.5 546.6 441.0 417.2 2395.7 279.2 192.6 229.6 1758.0 667.2 4579.3 123.7 685.2 2954.6 65.8 82.1 80.6 67.4 68.8 82.8 87.5 80.5 86.6 78.0 101.5 86.4 44.0 3.2 12.2 20.5 331.8 63.5 116.5 7.5 27.3 10.4 22.2 32.9 5.1 17.2 6.2 77.3 244.0 136.4 104.5 47.0 39.2 73.0 6.8 17.6 74.5 94.4 145.6 78.4 6.8 34.5 1402.6 59.9 181.0 29.8 141.8 126.0 189.2 6.6 595.3 25.2 14.1 77.8 2.0 1015.5 1146.3 10.8 8.1 1046.2 96.0 39.4 949.1 31.5 74.2 27.6 2.1 108.2 19.8 16.1 130.1 165.3 52.8 305.3 4.5 43.2 6.6 15.4 75.7 5.1 39.5 9.2 38.2 172.8 354.9 11.9 140.2 179.6 COX19 MGC104475 ENSG00000240230 "Cytochrome c oxidase assembly factor COX19" Q49B96 7 898778-975549 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021226 Approved Supported Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Cytosol "HPA021226: AB_1847176" "unprognostic (1.83e-1)" "unprognostic (1.16e-1)" "unprognostic (1.05e-2)" "unprognostic (3.76e-2)" "unprognostic (5.22e-2)" "unprognostic (1.05e-1)" "unprognostic (2.13e-2)" "unprognostic (1.61e-1)" "unprognostic (3.96e-1)" "unprognostic (5.60e-2)" "unprognostic (4.79e-2)" "unprognostic (3.36e-2)" "unprognostic (2.37e-3)" "unprognostic (2.49e-2)" "unprognostic (1.64e-1)" "unprognostic (2.74e-1)" "unprognostic (9.14e-3)" 4.5 12.3 4.0 3.2 4.7 6.7 4.4 6.3 4.8 5.4 2.2 6.8 5.3 4.8 2.2 5.8 6.8 2.0 5.2 4.0 4.3 6.2 5.9 4.9 4.4 4.8 4.2 5.5 7.5 6.4 5.9 2.7 5.0 6.2 3.5 2.9 6.0 2.8 7.5 8.0 7.4 2.4 3.6 7.6 5.9 4.0 4.4 3.7 5.6 4.9 3.5 5.0 4.8 6.9 13.9 3.7 4.1 5.2 3.1 4.4 7.8 6.1 4.4 5.2 4.3 9.6 7.6 6.8 2.0 3.7 8.2 9.1 4.3 4.2 4.1 2.1 7.2 3.0 4.5 7.1 9.8 7.3 6.8 5.1 9.7 4.0 9.2 5.8 3.3 6.9 9.0 5.7 3.4 9.0 3.1 8.6 10.6 16.3 8.6 7.4 0.9 3.3 4.6 6.0 5.4 5.4 3.5 14.4 12.0 6.7 7.2 17.1 4.2 5.2 7.6 6.0 9.5 7.1 5.2 6.6 4.6 10.4 8.7 9.4 5.2 8.3 5.8 5.1 5.9 6.6 6.1 5.2 4.5 6.1 7.5 7.2 5.0 5.4 5.5 7.9 5.9 4.4 4.0 4.7 6.3 4.8 4.0 4.3 4.8 4.2 5.0 3.6 4.4 6.9 25.4 12.8 21.4 6.2 35.4 24.6 35.9 37.7 19.4 19.3 21.7 19.2 14.2 31.5 24.1 31.3 12.5 27.8 49.7 29.9 15.6 34.9 7.4 58.4 23.8 23.5 44.9 17.2 13.1 34.0 41.8 19.0 17.3 49.3 34.9 28.1 25.0 31.0 26.1 15.2 13.3 32.6 36.7 24.9 28.5 2.7 19.6 29.4 21.4 13.1 46.6 33.3 64.9 6.6 22.7 49.6 31.7 14.3 20.8 36.8 37.7 25.8 36.2 27.0 6.6 18.7 23.2 19.2 32.7 21.4 25.7 41.9 39.5 30.9 32.2 45.3 CPEB2 ENSG00000137449 "Cytoplasmic polyadenylation element binding protein 2" Q7Z5Q1 4 15002481-15070153 "Predicted intracellular proteins" "Translation regulation" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 127.6;Oligodendrocytes: 406.5;Suprabasal keratinocytes: 129.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 57.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072513 Approved Cytosol Yes No "Cluster 40: NK-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA072513: AB_2686529" "unprognostic (6.59e-2)" "unprognostic (4.21e-3)" "unprognostic (4.75e-2)" "unprognostic (2.60e-1)" "unprognostic (1.06e-1)" "unprognostic (1.80e-2)" "unprognostic (2.36e-2)" "unprognostic (5.67e-3)" "unprognostic (1.33e-1)" "unprognostic (1.65e-1)" "unprognostic (4.58e-2)" "unprognostic (2.06e-1)" "unprognostic (8.62e-2)" "unprognostic (1.09e-1)" "unprognostic (1.28e-1)" "unprognostic (1.81e-1)" "unprognostic (8.34e-2)" 9.6 6.0 13.2 5.1 21.9 26.5 12.3 18.8 21.9 9.8 5.6 11.5 8.4 7.4 8.3 13.3 6.0 9.5 7.3 14.6 15.0 12.0 17.6 8.4 5.6 22.4 16.6 6.3 4.4 16.3 4.2 6.4 20.7 8.4 9.7 16.1 8.1 10.7 5.8 23.5 8.7 8.6 18.7 5.8 10.7 37.9 17.3 4.5 4.8 6.2 6.4 8.0 13.2 45.5 2.9 18.1 1.9 0.7 13.1 26.2 3.6 10.8 6.7 5.8 4.6 0.3 4.2 1.9 2.1 10.1 11.8 3.5 3.9 2.6 3.6 4.8 1.5 0.5 16.3 3.5 6.1 1.0 2.6 12.3 12.5 15.6 14.7 8.7 6.1 0.3 0.4 13.2 26.9 1.5 0.2 4.7 1.7 5.9 2.8 0.3 1.8 0.8 57.3 2.6 1.7 11.1 3.1 2.4 10.6 8.7 1.5 12.2 11.7 24.0 2.1 15.3 6.1 9.0 1.3 1.0 19.3 10.6 9.5 0.0 0.2 0.6 0.1 0.1 0.5 0.0 0.2 0.1 0.2 0.1 0.3 0.1 1.1 0.5 0.1 0.1 0.1 0.1 13.2 21.9 18.8 21.9 14.6 15.0 22.4 16.6 20.7 18.7 17.3 45.5 24.9 32.1 14.2 55.8 8.1 85.8 12.2 6.8 58.1 8.6 31.2 17.8 22.3 12.8 9.3 31.3 27.1 1.4 10.7 26.4 1.9 4.6 64.5 38.4 9.9 14.7 10.2 3.8 58.2 4.9 1.8 13.4 15.3 50.7 10.8 1.8 13.2 23.8 11.2 15.2 127.6 13.1 4.1 14.1 31.0 20.3 6.2 20.3 53.4 39.4 6.6 8.5 3.1 89.5 406.5 7.0 16.9 8.2 17.5 11.8 18.7 14.8 5.1 19.3 0.0 20.7 16.5 16.6 4.6 77.0 129.4 1.4 11.0 3.6 8.1 17.0 CPLANE1 "C5orf42, FLJ13231, Hug, JBTS17" ENSG00000197603 "Ciliogenesis and planar polarity effector 1" Q9H799 5 37106228-37249376 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 19.4;Collecting duct cells: 22.0;Endometrial ciliated cells: 50.3;Endometrial stromal cells: 42.9;Glandular and luminal cells: 20.6;Granulosa cells: 40.8;Theca cells: 18.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 21.9;SiHa: 48.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036775, HPA036776" Approved Approved Cytosol NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA036775: AB_10669914, HPA036776: AB_2675308" "unprognostic (3.06e-1)" "unprognostic (2.00e-1)" "unprognostic (4.96e-2)" "unprognostic (4.13e-3)" "unprognostic (1.65e-1)" "unprognostic (1.44e-2)" "unprognostic (1.38e-3)" "unprognostic (5.88e-2)" "unprognostic (3.13e-2)" "unprognostic (6.20e-3)" "unprognostic (3.02e-1)" "unprognostic (5.31e-2)" "unprognostic (2.72e-2)" "unprognostic (2.85e-2)" "unprognostic (2.16e-1)" "unprognostic (3.44e-2)" "unprognostic (2.09e-1)" 2.4 3.1 1.4 1.4 1.9 1.0 3.8 2.6 2.7 3.4 2.5 1.9 1.0 4.2 3.7 2.3 4.2 3.2 1.8 1.4 1.8 3.6 1.5 3.3 1.7 1.3 1.3 5.3 2.4 5.4 2.2 3.3 0.6 4.3 2.0 5.7 2.9 3.6 1.4 2.3 1.1 3.2 0.3 2.3 2.2 4.8 2.5 6.3 6.9 3.3 1.7 2.7 1.4 2.8 5.7 3.5 8.4 6.4 11.4 10.3 3.7 5.8 4.2 6.6 5.2 4.0 7.6 1.4 3.7 5.2 10.4 2.7 2.4 3.5 6.5 3.8 2.6 3.3 21.9 2.4 5.8 0.0 1.8 7.8 4.7 6.7 3.5 7.8 6.5 3.6 0.0 1.2 11.8 0.0 4.2 4.8 2.2 0.0 2.7 4.0 14.9 0.0 6.0 1.7 4.7 3.3 48.7 0.3 3.1 6.8 2.6 3.5 8.0 10.0 6.2 2.7 4.5 1.7 0.0 1.6 2.4 0.1 3.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.3 0.0 0.0 1.4 1.9 2.6 2.7 1.4 1.8 1.3 1.3 0.6 0.3 2.5 2.8 19.4 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 11.3 8.9 0.0 0.0 0.0 22.0 0.0 7.4 8.8 0.0 0.0 8.8 0.0 50.3 42.9 4.8 0.0 0.0 0.0 5.3 5.8 7.6 0.0 20.6 0.0 40.8 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 2.6 0.0 0.0 3.9 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 3.6 3.2 18.9 0.0 0.0 CPNE5 "COPN5, CPN5, KIAA1599" ENSG00000124772 "Copine 5" Q9HCH3 6 36740775-36839444 "Plasma proteins, Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 62.4;heart muscle: 92.7" "Cell type enhanced" "Detected in many" "B-cells: 50.6;Cardiomyocytes: 30.0;Excitatory neurons: 35.1;Oligodendrocyte precursor cells: 36.7;Plasma cells: 89.6" "Cancer enhanced" "Detected in all" "glioma: 11.3" "Region enhanced" "Detected in many" "basal ganglia: 62.4" "Group enriched" "Detected in some" 80 "memory B-cell: 51.6;naive B-cell: 26.8" "Lineage enriched" "Detected in single" 105 "B-cells: 51.6" "Group enriched" "Detected in some" 5 "Daudi: 59.4;HUVEC TERT2: 25.7;U-266/70: 19.7;U-266/84: 17.1;U-698: 28.1" "Region enhanced" "Detected in many" "basal ganglia: 103.3" "Region enhanced" "Detected in many" "basal ganglia: 135.5" HPA031369 Enhanced Approved Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "HPA031369: AB_10601801" "unprognostic (5.71e-3)" "unprognostic (1.07e-2)" "unprognostic (1.33e-1)" "unprognostic (2.73e-2)" "unprognostic (1.04e-1)" "prognostic favorable (2.87e-5)" "unprognostic (1.07e-1)" "unprognostic (3.07e-2)" "unprognostic (9.57e-2)" "unprognostic (1.21e-3)" "unprognostic (2.45e-1)" "unprognostic (4.10e-2)" "prognostic unfavorable (6.00e-5)" "unprognostic (1.68e-2)" "unprognostic (3.80e-1)" "unprognostic (2.00e-1)" "unprognostic (3.57e-1)" 6.4 0.9 16.6 10.7 62.4 1.4 2.3 0.0 29.5 3.9 0.0 6.2 5.6 5.8 1.0 2.4 19.9 2.0 92.7 23.0 2.7 4.5 0.8 2.6 23.6 0.0 4.6 6.6 1.0 0.4 11.0 1.4 0.0 5.8 5.0 2.8 3.5 2.5 0.5 1.8 8.6 4.7 1.1 20.0 5.1 25.3 0.8 2.3 3.3 0.2 28.1 4.9 5.7 13.3 0.9 0.0 0.5 0.1 0.1 0.0 0.3 0.2 0.2 0.3 0.5 0.0 0.2 59.4 0.5 0.8 2.7 0.4 0.1 0.4 0.2 0.0 0.0 2.6 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.7 0.0 4.1 25.7 0.2 0.2 1.7 0.5 0.0 0.0 0.4 0.1 0.8 0.0 0.3 0.5 0.0 0.0 0.1 0.5 0.1 0.0 0.0 5.3 0.3 0.0 0.8 5.9 0.4 0.7 0.0 2.1 19.7 17.1 28.1 0.3 6.5 0.1 0.0 0.1 0.0 0.0 0.2 0.2 51.6 0.2 0.0 0.1 26.8 0.0 0.0 0.4 0.0 0.2 0.3 0.0 4.5 16.6 62.4 0.0 29.5 23.0 2.7 0.0 4.6 0.0 1.1 0.8 13.3 2.8 0.0 3.6 1.3 50.6 0.6 0.2 0.2 0.0 13.4 0.3 0.5 30.0 0.0 0.0 0.0 0.0 0.0 1.5 15.1 1.9 0.0 3.3 0.4 0.8 7.4 4.2 0.0 35.1 0.2 0.0 2.8 1.5 1.4 12.6 0.3 5.0 1.0 0.4 0.0 8.6 1.8 0.0 1.9 0.6 4.8 0.0 6.2 3.6 2.8 0.2 1.3 2.1 36.7 0.8 0.5 12.5 0.4 89.6 0.2 2.3 0.1 0.0 1.6 0.0 2.3 1.0 0.8 1.5 1.1 0.1 0.0 2.0 0.2 1.7 0.4 CPTP "GLTPD1, MGC10334" ENSG00000224051 "Ceramide-1-phosphate transfer protein" Q5TA50 1 1324756-1328896 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 72.5;Late spermatids: 167.1;Proximal enterocytes: 72.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056832 Approved Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA056832: AB_2683251" "unprognostic (9.00e-2)" "unprognostic (2.19e-1)" "unprognostic (1.05e-1)" "unprognostic (1.17e-1)" "unprognostic (7.01e-2)" "unprognostic (1.94e-2)" "unprognostic (1.37e-1)" "unprognostic (1.90e-1)" "unprognostic (3.35e-1)" "unprognostic (1.52e-2)" "unprognostic (1.32e-2)" "unprognostic (2.79e-1)" "prognostic favorable (1.75e-4)" "unprognostic (1.27e-1)" "unprognostic (3.21e-2)" "unprognostic (1.25e-2)" "unprognostic (5.27e-2)" 15.7 19.5 14.1 6.0 13.0 2.8 16.9 13.1 22.1 17.6 14.0 28.3 19.8 14.2 8.5 48.9 12.5 3.7 92.8 15.0 10.9 28.4 69.9 12.6 5.4 16.0 13.8 10.8 18.6 14.1 8.0 4.6 17.1 19.1 4.8 2.0 37.2 6.5 55.2 33.0 23.2 2.7 12.3 21.2 31.3 70.7 15.4 4.0 14.2 22.8 4.4 14.7 24.8 11.8 36.0 12.7 6.0 11.0 5.7 4.8 9.7 18.4 9.8 17.1 11.1 17.4 19.6 14.2 20.9 8.5 11.3 26.3 4.8 10.9 6.2 16.8 16.5 10.6 13.6 17.7 14.4 10.3 10.3 9.3 8.3 18.0 5.0 8.3 9.1 9.0 15.8 8.3 5.7 13.3 11.4 12.1 5.5 9.3 55.1 14.0 9.8 41.1 14.0 9.5 14.2 14.9 14.8 46.3 32.8 3.1 16.5 7.1 15.5 18.3 12.8 20.1 15.2 18.1 14.8 14.8 17.6 15.1 5.6 1.8 1.2 6.1 1.6 0.6 0.9 2.9 1.9 1.5 0.8 1.5 1.1 0.9 1.6 1.2 1.2 1.2 5.1 1.4 14.1 13.0 13.1 22.1 15.0 10.9 16.0 13.8 17.1 12.3 15.4 11.8 20.0 0.0 3.2 2.0 7.2 0.0 7.8 0.0 5.2 9.7 15.8 8.6 22.6 12.8 1.3 7.3 0.0 18.6 10.8 35.3 39.2 25.9 72.5 5.9 4.9 13.8 6.1 5.5 3.0 24.3 21.3 7.0 26.5 9.4 0.0 9.1 13.9 31.5 16.4 23.5 3.3 14.0 0.0 7.6 0.0 167.1 12.2 6.3 0.0 5.6 15.8 16.3 18.6 2.0 2.7 49.3 13.3 9.8 18.6 12.0 72.0 18.2 0.0 7.0 13.1 4.7 6.8 52.3 4.8 14.0 0.0 19.6 7.5 9.8 18.4 9.1 CREB3 "Luman, LZIP, sLZIP" ENSG00000107175 "CAMP responsive element binding protein 3" O43889 9 35732598-35736999 "Predicted membrane proteins, Transcription factors" "Chemotaxis, Host-virus interaction, Transcription, Transcription regulation, Unfolded protein response" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 173.7;Late spermatids: 413.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030978 Supported Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA030978: AB_2673683" "unprognostic (1.73e-3)" "unprognostic (9.72e-2)" "unprognostic (9.32e-2)" "unprognostic (5.62e-3)" "unprognostic (3.61e-1)" "unprognostic (3.86e-2)" "prognostic unfavorable (5.57e-4)" "unprognostic (4.29e-2)" "unprognostic (4.63e-2)" "prognostic favorable (5.40e-4)" "unprognostic (1.13e-1)" "unprognostic (1.65e-1)" "prognostic favorable (3.77e-5)" "unprognostic (1.48e-1)" "unprognostic (1.61e-1)" "unprognostic (2.54e-1)" "unprognostic (1.29e-1)" 26.8 45.5 41.4 16.5 42.2 7.6 26.6 38.9 47.1 29.1 37.5 38.9 14.5 34.1 37.4 16.3 28.6 20.8 27.7 39.8 43.6 29.4 26.4 24.9 14.4 43.0 43.0 26.1 32.6 29.9 38.3 20.6 43.4 37.0 23.1 23.4 31.9 38.6 24.1 18.1 22.6 35.7 41.6 20.3 36.1 44.7 42.4 16.1 26.6 20.0 19.2 32.1 21.4 40.3 39.2 35.6 36.9 30.0 77.5 48.8 22.6 64.1 111.6 69.8 73.1 45.8 19.4 10.5 28.5 108.0 87.8 15.7 25.0 52.7 53.7 37.9 14.5 8.7 44.1 24.8 97.3 16.0 19.2 42.8 45.2 72.0 73.4 66.8 42.6 19.1 11.9 24.7 81.7 22.3 22.3 8.5 19.5 30.9 39.1 18.3 15.3 15.1 69.5 25.2 15.3 21.3 22.6 23.6 17.1 34.6 39.1 7.1 46.4 52.0 27.1 35.6 44.2 12.2 13.2 15.1 55.1 7.4 55.6 24.6 33.5 11.6 26.1 32.8 31.2 28.4 26.1 29.9 37.8 20.0 20.2 18.1 12.8 28.2 29.0 31.4 27.1 28.0 41.4 42.2 38.9 47.1 39.8 43.6 43.0 43.0 43.4 41.6 42.4 40.3 24.4 28.9 17.8 3.9 27.0 35.8 55.4 62.9 20.5 29.2 35.5 27.9 13.2 30.0 43.5 16.5 12.5 49.0 29.5 50.0 33.2 89.0 173.7 26.3 19.4 33.0 26.4 3.8 4.6 70.3 54.9 34.9 25.0 25.9 32.3 20.6 25.7 23.7 35.9 5.0 5.6 67.6 32.6 16.8 59.3 413.5 30.1 22.5 49.8 1.9 42.4 50.6 38.1 3.0 5.4 72.4 42.1 42.2 53.1 65.5 71.3 62.2 56.0 18.5 32.9 22.2 47.9 73.3 32.7 11.9 22.7 61.0 24.2 22.6 29.0 46.8 CRYGS CRYG8 ENSG00000213139 "Crystallin gamma S" P22914 3 186538441-186546702 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.5" "Cell type enhanced" "Detected in many" "Astrocytes: 5.2;Excitatory neurons: 5.4;Inhibitory neurons: 6.0;Microglial cells: 5.6;Oligodendrocyte precursor cells: 6.0;Oligodendrocytes: 7.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA035103, HPA063539" Supported Uncertain Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 43: Cardiomyocytes - Nuclear processes" Cytosol "HPA035103: AB_10696367, HPA063539: " "unprognostic (5.52e-4)" "unprognostic (1.29e-3)" "unprognostic (1.44e-2)" "unprognostic (5.45e-2)" "unprognostic (4.90e-2)" "unprognostic (5.85e-2)" "unprognostic (4.79e-2)" "unprognostic (1.73e-2)" "unprognostic (4.76e-2)" "unprognostic (1.12e-1)" "unprognostic (5.84e-3)" "unprognostic (1.51e-1)" "prognostic unfavorable (3.72e-9)" "unprognostic (1.10e-1)" "unprognostic (9.53e-2)" "unprognostic (3.67e-1)" "prognostic favorable (2.73e-4)" 1.1 2.0 6.5 1.0 6.9 2.8 1.6 8.0 10.5 1.8 6.9 1.7 1.1 1.6 1.5 1.2 1.5 0.8 2.1 6.5 7.2 2.3 2.1 1.5 2.2 6.5 6.8 1.2 2.1 0.7 1.4 0.9 7.0 1.5 2.0 8.1 1.2 1.4 1.1 1.1 1.9 1.3 6.3 2.8 1.5 2.1 6.8 4.8 1.2 0.6 1.7 1.7 1.6 7.3 0.3 0.7 1.5 1.1 1.5 1.7 0.0 0.2 0.4 0.5 1.0 0.2 0.6 1.5 1.3 1.2 0.6 1.0 0.8 1.1 1.6 1.0 1.8 1.7 0.2 1.1 0.6 1.1 1.3 1.9 1.2 0.3 0.8 1.7 1.5 1.6 0.4 0.8 1.2 0.4 0.8 0.5 0.0 0.5 0.3 1.7 0.2 0.8 0.5 1.0 0.5 0.6 0.2 0.7 0.3 1.0 0.9 0.9 2.2 0.4 0.3 0.5 1.0 1.7 1.1 1.8 0.7 0.5 0.6 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.5 6.9 8.0 10.5 6.5 7.2 6.5 6.8 7.0 6.3 6.8 7.3 1.2 0.0 1.7 5.2 0.7 0.3 0.3 0.7 0.6 1.1 0.9 1.5 3.0 1.5 0.9 0.0 2.1 0.2 0.6 0.5 0.0 0.6 0.2 0.3 0.6 1.0 0.0 3.2 5.4 0.2 0.2 0.9 2.6 0.5 1.3 0.9 2.5 1.3 0.4 1.7 6.0 0.8 2.0 0.3 1.2 1.3 0.3 1.1 0.0 5.6 0.1 0.5 1.0 6.0 7.6 0.2 0.4 0.7 0.1 0.3 0.8 0.2 0.5 3.2 0.0 0.8 0.8 2.4 0.9 0.4 0.1 0.3 0.8 0.9 1.2 0.2 CRYM DFNA40 ENSG00000103316 "Crystallin mu" Q14894 16 21238874-21303083 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 78.7;heart muscle: 175.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 126.0;Ionocytes: 114.0;Muller glia cells: 640.7;Proximal tubular cells: 190.1" "Cancer enhanced" "Detected in many" "prostate cancer: 14.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 21 "plasmacytoid DC: 82.0" "Lineage enriched" "Detected in many" 21 "dendritic cells: 82.0" "Cell line enriched" "Detected in some" 4 "RPTEC TERT1: 100.3" "Group enriched" "Detected in all" 11 "amygdala: 124.0;basal ganglia: 275.1;cerebral cortex: 124.7;hippocampal formation: 324.3;white matter: 128.4" "Low region specificity" "Detected in all" "HPA019086, HPA030619" Enhanced Supported Cytosol NA NA 150000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 5: Muller glia cells - Visual perception" Cytosol "HPA019086: AB_1847260, HPA030619: AB_2673551" "unprognostic (1.32e-1)" "unprognostic (2.93e-3)" "unprognostic (8.96e-2)" "unprognostic (1.44e-1)" "unprognostic (2.13e-1)" "unprognostic (4.62e-2)" "unprognostic (2.88e-1)" "unprognostic (5.75e-3)" "unprognostic (2.81e-1)" "unprognostic (7.37e-2)" "unprognostic (2.05e-2)" "unprognostic (5.95e-2)" "unprognostic (2.11e-3)" "unprognostic (7.79e-3)" "unprognostic (2.49e-2)" "unprognostic (1.87e-3)" "unprognostic (1.31e-1)" 1.9 0.8 37.4 0.9 78.7 1.0 2.7 40.6 62.2 3.7 13.6 6.9 1.6 1.0 0.2 7.6 1.1 7.0 175.3 54.0 31.6 64.4 14.2 8.5 1.1 13.9 19.8 0.3 1.8 8.9 55.6 0.4 15.6 35.4 8.4 54.7 20.6 0.2 13.4 4.1 2.6 0.3 14.1 0.3 1.3 5.1 20.5 0.3 0.4 0.9 3.8 21.8 3.6 31.3 0.2 4.0 0.0 0.0 0.2 0.4 0.7 0.0 2.1 0.1 0.2 0.2 0.2 0.3 1.0 0.0 1.8 0.6 5.4 0.0 0.0 0.0 0.8 23.2 0.1 2.3 0.0 0.1 2.2 0.8 0.0 0.8 1.0 0.0 0.0 0.5 0.0 0.4 0.7 0.3 0.0 0.9 9.7 1.6 0.1 0.1 0.0 0.5 100.3 0.1 3.7 5.2 0.2 0.1 2.6 4.8 0.1 0.0 0.0 0.5 0.7 6.8 0.0 0.2 0.0 0.5 16.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.2 0.0 0.0 0.1 3.9 0.0 0.0 0.3 0.0 0.0 82.0 0.0 1.2 37.4 78.7 40.6 62.2 54.0 31.6 13.9 19.8 15.6 14.1 20.5 31.3 0.3 0.0 20.1 5.2 4.1 2.3 25.4 16.3 0.0 6.3 0.4 11.7 126.0 2.8 56.1 14.7 4.2 0.0 11.4 7.1 17.6 0.1 19.7 3.2 1.5 3.0 13.1 4.8 43.8 0.0 0.0 7.1 6.1 7.7 1.3 1.3 0.4 8.3 0.1 1.7 5.9 20.6 114.0 1.6 0.7 12.4 0.0 1.5 33.8 10.3 0.7 640.7 0.0 7.1 6.6 0.4 2.8 0.0 0.3 19.0 7.5 190.1 19.9 26.2 0.0 0.2 4.3 6.7 7.3 0.2 1.3 0.1 1.1 0.1 8.2 68.0 CRYZ ENSG00000116791 "Crystallin zeta" Q08257 1 74705482-74733408 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Oxidoreductase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 331.0;liver: 282.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 160.0;Distal tubular cells: 226.9;Hepatocytes: 200.6;Proximal tubular cells: 526.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 439.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021921, HPA023290" Approved Supported Cytosol NA NA 6400000 "Cluster 44: Non-specific - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA021921: AB_1847262, HPA023290: AB_1847263" "unprognostic (3.64e-2)" "unprognostic (3.38e-2)" "unprognostic (1.97e-1)" "unprognostic (1.27e-2)" "unprognostic (5.32e-3)" "unprognostic (5.79e-2)" "unprognostic (6.29e-2)" "unprognostic (1.04e-1)" "unprognostic (4.56e-2)" "unprognostic (1.06e-1)" "unprognostic (6.38e-3)" "unprognostic (2.19e-1)" "unprognostic (1.35e-3)" "unprognostic (3.12e-1)" "unprognostic (7.50e-2)" "unprognostic (2.94e-1)" "unprognostic (7.32e-2)" 19.8 34.2 19.2 12.9 19.8 2.2 39.0 19.3 36.0 54.6 54.2 21.4 51.2 40.8 120.6 29.0 50.0 68.9 45.6 21.6 23.3 331.0 282.9 32.4 24.4 21.3 24.9 31.6 64.6 52.9 17.0 16.8 24.4 38.8 22.0 15.3 25.0 56.9 25.1 22.2 44.0 40.1 21.1 19.4 25.1 9.2 24.5 33.9 44.5 23.0 23.8 40.8 21.7 24.9 12.1 112.2 57.6 16.3 64.4 70.2 38.6 36.5 57.1 51.8 57.4 88.9 46.1 64.9 62.0 71.3 92.2 31.0 47.2 46.0 83.6 75.2 19.2 27.0 32.2 179.0 33.8 23.1 52.6 33.1 40.0 82.8 15.1 49.1 43.7 35.9 85.9 22.8 109.2 27.0 42.3 38.6 43.1 93.6 72.6 26.8 53.6 23.7 439.4 36.0 15.9 27.9 8.5 60.1 41.2 64.3 54.0 7.7 21.9 12.3 30.7 38.8 55.7 16.2 33.3 32.1 99.4 9.0 35.6 13.1 9.4 1.9 32.1 15.1 26.2 32.8 31.6 30.3 17.1 26.5 27.4 29.5 1.5 30.3 17.9 14.4 42.3 18.8 19.2 19.8 19.3 36.0 21.6 23.3 21.3 24.9 24.4 21.1 24.5 24.9 6.9 28.9 22.6 4.9 20.4 17.8 28.0 32.4 24.5 4.0 16.8 16.8 32.3 84.4 15.7 160.0 2.1 13.5 8.6 6.6 226.9 53.8 0.2 54.8 7.8 8.0 6.7 8.4 4.5 32.4 18.1 20.7 20.9 27.0 14.5 7.8 12.8 200.6 18.5 0.0 4.4 12.0 8.2 15.7 13.7 2.1 20.8 11.4 10.6 4.7 7.1 7.7 11.3 7.1 9.1 31.2 14.5 20.7 20.5 10.2 79.1 526.6 17.3 2.9 0.0 10.6 16.2 1.7 7.4 19.7 21.2 7.3 16.9 13.8 16.2 17.0 CSNK1A1 "CK1, CK1a, CK1alpha, CKIa, CKIalpha" ENSG00000113712 "Casein kinase 1 alpha 1" P48729 5 149492982-149551471 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 847.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016680, HPA051334" Uncertain Approved Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB016680: AB_1614518, HPA051334: AB_2681446" "unprognostic (4.27e-3)" "unprognostic (5.85e-3)" "prognostic favorable (1.15e-4)" "unprognostic (7.39e-2)" "unprognostic (2.66e-1)" "unprognostic (3.14e-1)" "unprognostic (1.27e-2)" "unprognostic (5.56e-2)" "unprognostic (4.38e-1)" "unprognostic (8.31e-2)" "prognostic unfavorable (5.79e-4)" "unprognostic (5.47e-2)" "unprognostic (1.56e-1)" "unprognostic (7.92e-2)" "unprognostic (4.41e-2)" "unprognostic (6.28e-3)" "unprognostic (6.92e-2)" 77.0 67.6 49.0 67.3 53.9 210.8 97.8 60.0 52.7 67.9 61.5 83.2 56.6 73.7 60.2 142.4 56.6 79.7 87.6 48.6 55.9 50.3 68.2 69.6 60.0 61.3 56.4 53.2 55.0 99.4 48.8 71.7 56.6 88.3 68.2 57.6 71.3 69.2 104.1 121.4 63.1 82.9 57.9 60.7 73.5 45.6 57.8 81.0 76.9 59.5 81.8 94.8 82.3 66.3 154.4 106.4 151.0 144.1 143.6 191.4 185.0 189.7 176.8 146.0 153.5 194.1 187.0 71.6 221.3 183.3 140.7 153.9 101.2 292.5 184.1 124.6 78.0 96.9 96.6 87.8 143.1 163.9 148.4 158.5 313.4 148.1 269.0 163.9 184.7 137.2 102.2 116.0 140.7 104.4 152.2 66.6 71.4 167.6 247.3 129.0 96.1 98.9 112.3 248.3 123.5 110.5 151.1 193.3 200.8 135.6 194.1 134.4 164.6 168.6 83.6 118.2 197.1 117.0 149.2 100.6 169.2 95.6 216.9 106.0 72.6 66.6 47.5 68.9 51.6 50.2 58.1 49.7 80.0 39.9 61.4 55.2 61.1 63.7 67.8 47.4 76.7 94.7 49.0 53.9 60.0 52.7 48.6 55.9 61.3 56.4 56.6 57.9 57.8 66.3 169.7 147.4 176.7 137.1 101.8 684.5 583.1 270.0 187.8 135.8 257.0 158.4 63.5 90.1 298.1 115.8 64.6 171.2 135.6 126.8 92.0 167.1 95.7 195.8 193.5 191.1 129.9 146.7 108.4 184.1 223.7 159.8 124.4 285.2 117.6 114.0 216.4 108.9 136.1 151.4 115.4 141.9 154.6 167.8 311.5 87.5 104.1 183.8 152.9 119.0 156.6 156.9 108.1 168.4 198.1 197.2 113.9 111.7 105.4 368.6 120.4 102.8 276.7 109.6 157.8 190.2 216.1 181.9 88.9 272.4 847.7 350.9 133.5 177.0 115.7 485.2 CSNK1A1L MGC33182 ENSG00000180138 "Casein kinase 1 alpha 1 like" Q8N752 13 37103259-37105664 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 3.5" "Group enriched" "Detected in some" 6 "Early spermatids: 30.0;Late spermatids: 23.0;Spermatocytes: 16.1" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 33 "neutrophil: 7.6" "Lineage enriched" "Detected in single" 39 "granulocytes: 7.6" "Not detected" "Not detected" HPA051334 Uncertain Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 78: Testis - Spermatogenesis" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA051334: AB_2681446" "unprognostic (1.23e-2)" "unprognostic (1.59e-1)" "unprognostic (3.19e-2)" "unprognostic (3.54e-2)" "unprognostic (2.40e-2)" "unprognostic (5.40e-2)" "unprognostic (8.90e-2)" "unprognostic (3.47e-1)" "unprognostic (1.47e-3)" "unprognostic (4.50e-1)" "unprognostic (2.02e-1)" "unprognostic (2.28e-3)" "unprognostic (3.45e-1)" "unprognostic (2.38e-1)" 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 7.6 0.1 0.1 0.0 0.1 0.2 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.1 1.8 3.5 0.2 0.0 0.0 0.0 0.0 2.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 30.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.7 23.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.6 2.2 16.1 1.2 0.0 2.7 0.3 0.0 0.0 0.1 1.7 CSNK1G1 CK1gamma1 ENSG00000169118 "Casein kinase 1 gamma 1" Q9HCP0 15 64165525-64356173 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 35.0" "Cell type enhanced" "Detected in all" "Early spermatids: 130.6;Late spermatids: 261.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018209 Supported Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA018209: AB_1847278" "unprognostic (9.10e-2)" "unprognostic (8.09e-2)" "unprognostic (1.20e-1)" "unprognostic (2.65e-2)" "unprognostic (1.20e-1)" "unprognostic (1.64e-1)" "unprognostic (7.90e-3)" "unprognostic (3.07e-1)" "unprognostic (1.61e-2)" "unprognostic (2.02e-1)" "unprognostic (8.63e-2)" "unprognostic (3.75e-2)" "unprognostic (7.51e-2)" "unprognostic (8.16e-3)" "unprognostic (1.31e-1)" "unprognostic (2.59e-2)" "unprognostic (2.41e-1)" 4.0 3.4 6.1 6.1 6.9 9.0 6.0 6.4 7.7 5.4 6.3 5.0 3.9 4.5 6.7 7.9 7.3 4.0 2.9 10.4 7.1 5.3 2.9 5.3 5.9 2.8 4.3 5.2 4.1 6.3 4.7 4.9 2.6 3.7 5.4 14.5 3.6 4.4 4.1 6.6 3.8 5.3 3.6 5.9 4.3 35.0 6.8 9.3 7.9 3.3 6.8 5.5 4.6 4.9 6.8 14.2 10.0 13.2 8.3 11.4 8.9 8.3 8.5 13.8 12.5 11.5 13.2 10.8 4.3 13.3 14.2 15.4 26.7 16.5 16.1 20.6 6.8 10.1 11.2 8.0 9.8 18.9 11.4 10.3 21.7 14.0 20.0 11.9 15.4 10.6 12.3 10.4 12.8 9.4 9.7 5.8 9.4 8.9 7.4 16.1 12.5 8.6 11.2 26.8 16.2 9.9 11.1 6.5 9.5 16.4 11.4 7.4 16.8 12.6 14.9 9.8 10.5 12.3 26.0 8.8 11.6 13.5 7.9 0.4 1.9 3.1 2.8 2.8 4.0 1.8 2.5 2.1 1.4 1.8 2.4 2.3 4.5 2.8 2.3 2.1 2.2 1.3 6.1 6.9 6.4 7.7 10.4 7.1 2.8 4.3 2.6 3.6 6.8 4.9 10.9 28.9 11.3 35.6 12.9 11.6 10.5 13.7 19.9 47.1 11.6 7.9 7.3 11.5 12.7 5.5 68.8 6.9 12.6 12.2 1.9 9.6 130.6 37.4 17.9 12.2 22.8 7.8 69.4 7.0 9.0 10.3 15.3 24.6 3.8 15.8 10.4 4.4 10.4 10.1 49.8 10.5 6.1 9.7 10.0 261.1 6.2 14.1 7.2 40.3 13.5 7.9 5.2 40.2 41.3 12.0 7.5 10.1 14.3 11.1 8.2 9.7 23.3 29.3 6.6 14.4 11.8 31.9 19.8 26.7 15.6 4.1 13.2 7.9 10.4 13.2 CTBS CTB ENSG00000117151 Chitobiase Q01459 1 84549611-84574480 "Plasma proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "Low region specificity" "Detected in all" "Region enriched" "Detected in some" 7 "basal ganglia: 7.4" "CAB017043, HPA023594, HPA048810" Approved Uncertain Cytosol "Intracellular and membrane" NA NA 370000000 "Cluster 34: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "CAB017043: , HPA023594: AB_1847311, HPA048810: " "unprognostic (7.76e-2)" "unprognostic (1.28e-2)" "unprognostic (1.11e-1)" "unprognostic (1.36e-1)" "unprognostic (9.36e-2)" "unprognostic (3.54e-1)" "unprognostic (2.92e-1)" "unprognostic (1.76e-1)" "unprognostic (1.81e-1)" "unprognostic (1.84e-1)" "unprognostic (9.23e-2)" "unprognostic (1.27e-1)" "unprognostic (2.94e-2)" "unprognostic (7.08e-2)" "unprognostic (4.89e-2)" "unprognostic (3.12e-1)" "unprognostic (4.04e-2)" 1.5 1.4 0.4 1.4 0.8 3.3 1.6 1.0 0.6 1.2 2.1 1.2 0.9 1.5 3.1 1.0 1.1 1.2 1.0 0.2 0.6 1.7 3.7 1.4 1.6 1.3 0.9 0.8 1.7 1.6 0.5 1.2 1.5 2.2 1.4 1.4 3.3 0.8 0.8 2.4 1.2 1.1 0.5 2.5 1.4 0.5 0.8 1.0 1.3 0.9 1.0 1.0 0.5 1.3 0.9 0.3 0.2 0.2 2.7 3.2 0.6 0.6 2.2 0.3 0.8 0.1 1.1 1.2 0.2 1.4 0.3 0.4 0.0 0.9 0.9 1.1 0.3 0.8 0.1 0.1 1.6 0.8 0.4 2.4 1.6 0.8 1.2 1.9 0.9 0.5 0.7 2.2 0.6 0.0 0.5 0.9 0.2 0.2 0.3 0.2 0.3 0.8 1.9 0.4 0.1 0.4 0.2 0.9 1.1 0.5 0.5 0.9 1.5 1.1 0.1 1.5 0.7 0.6 0.2 0.3 0.8 1.1 0.8 0.5 0.1 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.7 0.1 0.3 0.1 0.0 0.0 0.4 0.8 1.0 0.6 0.2 0.6 1.3 0.9 1.5 0.5 0.8 1.3 43.6 9.6 23.4 10.4 37.4 30.3 30.2 28.0 34.1 5.9 33.1 15.6 5.8 31.5 25.5 23.9 41.7 26.8 25.4 30.2 43.0 20.2 3.3 24.1 24.4 29.9 23.0 14.1 6.2 19.2 24.2 28.1 25.0 19.4 43.8 9.7 49.6 70.8 48.2 3.3 4.3 18.9 16.2 75.5 27.9 3.7 21.1 58.8 7.2 20.6 56.5 21.8 18.6 5.5 9.0 19.1 25.2 24.5 59.8 36.7 30.0 44.4 38.2 41.9 13.1 20.2 16.6 10.4 12.8 27.3 24.7 25.6 26.8 25.3 18.4 29.9 CTIF KIAA0427 ENSG00000134030 "Cap binding complex dependent translation initiation factor" O43310 18 48539031-48863217 "Predicted intracellular proteins, Transporters" "Nonsense-mediated mRNA decay, Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 94.7;Excitatory neurons: 76.4;Inhibitory neurons: 80.6;Oligodendrocyte precursor cells: 75.9;Oligodendrocytes: 59.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016865, HPA024801" Uncertain Supported Cytosol NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" Cytosol "HPA016865: AB_1852311, HPA024801: AB_1852312" "unprognostic (5.84e-2)" "unprognostic (5.86e-2)" "unprognostic (2.27e-2)" "unprognostic (1.23e-2)" "unprognostic (2.06e-1)" "unprognostic (2.57e-1)" "unprognostic (1.31e-1)" "unprognostic (1.44e-1)" "unprognostic (8.86e-2)" "unprognostic (1.95e-3)" "unprognostic (2.77e-3)" "unprognostic (1.35e-1)" "prognostic favorable (3.18e-4)" "unprognostic (1.95e-1)" "unprognostic (1.99e-1)" "unprognostic (2.34e-3)" "unprognostic (7.33e-3)" 35.3 20.0 15.7 3.3 13.9 2.0 24.3 10.7 23.2 14.0 0.0 26.0 2.5 21.5 2.6 11.4 16.3 7.5 24.8 16.0 15.5 11.1 24.8 14.3 1.3 20.7 17.4 28.0 9.8 4.6 12.4 4.3 23.3 13.9 1.6 7.4 11.0 5.4 15.8 14.0 9.9 7.0 9.1 6.7 19.6 7.3 19.0 1.4 10.7 4.3 1.0 26.1 12.6 16.7 3.2 3.4 4.5 5.8 11.3 6.0 2.5 15.9 13.2 12.4 11.2 3.5 1.9 0.0 3.5 22.0 5.2 6.7 3.3 9.0 5.3 0.0 2.7 1.4 7.9 8.4 21.6 2.6 4.5 8.4 14.5 7.8 13.8 8.9 8.9 4.1 4.0 9.8 8.0 1.7 0.9 2.0 2.2 3.4 2.8 1.6 5.2 4.2 3.7 4.3 9.6 9.7 5.6 6.0 4.5 3.8 3.8 3.1 18.1 11.4 10.5 3.4 2.9 3.3 4.2 0.0 10.1 1.6 5.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 13.9 10.7 23.2 16.0 15.5 20.7 17.4 23.3 9.1 19.0 16.7 7.3 35.3 3.7 94.7 1.9 3.3 2.1 3.5 2.8 25.6 11.2 8.4 16.0 5.7 5.6 7.3 16.7 1.9 0.8 4.6 7.9 5.1 11.1 1.7 7.7 8.5 3.5 0.4 76.4 4.8 2.8 13.1 7.1 3.6 4.5 19.5 7.5 23.0 4.2 11.8 80.6 3.5 4.1 6.4 2.7 19.3 25.1 5.0 3.6 30.0 1.5 3.6 3.1 75.9 59.7 5.7 2.7 50.8 4.8 3.0 5.9 5.8 4.7 8.8 6.6 8.8 9.4 2.3 1.8 3.5 2.3 1.2 0.7 34.7 3.3 3.3 CUL9 "H7AP1, KIAA0708, PARC" ENSG00000112659 "Cullin 9" Q8IWT3 6 43182184-43224587 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 53 "Early spermatids: 513.7;Late spermatids: 1508.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016434, HPA052004" Approved Approved Cytosol No No "Cluster 39: Non-specific - mRNA processing" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA016434: AB_1848125, HPA052004: AB_2681690" "prognostic favorable (5.28e-4)" "unprognostic (1.47e-2)" "prognostic unfavorable (2.48e-4)" "unprognostic (5.20e-3)" "unprognostic (1.56e-1)" "prognostic favorable (2.37e-5)" "unprognostic (3.05e-3)" "unprognostic (1.83e-2)" "unprognostic (2.53e-2)" "unprognostic (1.29e-1)" "prognostic favorable (8.07e-4)" "unprognostic (8.22e-3)" "unprognostic (2.03e-1)" "unprognostic (2.68e-1)" "unprognostic (2.31e-1)" "unprognostic (9.94e-2)" "prognostic favorable (4.87e-4)" 2.9 3.0 3.1 4.9 4.5 6.9 2.9 1.3 3.4 3.2 3.5 3.6 4.0 3.3 1.7 5.5 4.9 3.6 2.6 3.2 2.0 3.1 2.1 3.6 6.3 2.4 2.8 4.3 4.2 5.5 2.9 2.4 2.7 3.4 2.3 3.2 3.9 4.0 2.8 8.0 4.2 2.8 1.5 4.9 4.2 5.2 2.5 7.6 5.2 2.9 4.7 3.8 2.7 2.7 8.2 6.0 3.2 7.7 8.8 5.2 4.4 3.2 5.6 5.0 4.6 1.9 3.4 6.8 6.0 5.1 4.5 5.8 2.7 6.7 2.3 8.3 2.5 7.4 6.8 3.0 5.8 4.7 11.6 7.1 13.8 4.1 3.7 4.4 7.4 11.5 3.9 8.7 4.5 7.2 9.6 6.8 0.6 15.7 3.6 13.9 2.2 6.6 3.8 8.4 5.5 7.8 4.2 5.0 7.2 2.7 8.6 10.4 6.9 12.5 8.6 3.7 6.1 8.3 8.3 5.5 3.2 8.2 5.7 0.0 0.2 0.0 0.2 0.1 0.2 0.1 0.1 0.5 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.4 0.2 3.1 4.5 1.3 3.4 3.2 2.0 2.4 2.8 2.7 1.5 2.5 2.7 6.6 0.0 8.2 16.3 7.5 6.4 2.7 9.3 16.5 10.2 8.0 6.1 6.9 8.6 5.9 3.7 12.5 3.4 6.5 8.8 3.9 4.2 513.7 7.5 5.5 6.8 6.0 3.4 15.8 6.2 1.7 5.3 18.8 6.4 2.5 14.6 9.3 6.4 11.6 11.8 11.9 7.9 6.1 9.6 5.0 1508.3 11.1 8.5 3.6 9.4 6.3 9.6 5.2 11.6 11.2 6.5 2.1 8.2 4.1 2.3 8.5 6.7 8.5 10.0 13.1 6.4 3.6 14.5 10.1 14.2 5.5 2.6 7.1 5.6 7.2 2.9 CYP26B1 P450RAI-2 ENSG00000003137 "Cytochrome P450 family 26 subfamily B member 1" Q9NR63 2 72129238-72147862 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.9;skin 1: 31.4" "Group enriched" "Detected in many" 4 "Leydig cells: 75.8;Peritubular cells: 229.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 9.8;HaCaT: 14.8;RH-30: 18.4;U-2 OS: 19.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA012567 Uncertain Approved Cytosol "Intracellular and membrane" No No "Cluster 27: Brain & Skin - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA012567: AB_1847429" "unprognostic (1.70e-1)" "unprognostic (1.05e-1)" "unprognostic (8.76e-2)" "unprognostic (2.19e-4)" "unprognostic (3.46e-2)" "unprognostic (4.40e-1)" "unprognostic (2.17e-4)" "unprognostic (8.41e-2)" "unprognostic (1.51e-1)" "unprognostic (1.40e-1)" "unprognostic (7.55e-3)" "unprognostic (1.52e-1)" "unprognostic (2.62e-2)" "unprognostic (1.77e-1)" "unprognostic (1.55e-1)" "unprognostic (9.44e-3)" "unprognostic (2.04e-2)" 26.2 4.3 12.0 1.9 3.3 0.1 15.0 12.3 7.0 5.0 0.4 3.2 3.7 2.5 1.5 3.9 5.5 1.1 8.5 6.7 1.3 8.8 1.0 2.7 4.9 48.0 10.4 4.5 0.6 0.8 9.3 3.3 49.9 2.6 1.2 4.2 9.9 7.3 5.9 31.4 4.7 1.6 0.0 3.5 1.2 13.8 0.7 19.3 14.4 2.3 2.9 3.2 4.2 3.5 0.6 5.9 0.0 0.1 9.8 4.0 5.9 0.9 0.1 0.2 0.2 1.8 0.5 0.0 0.5 0.7 3.0 14.8 8.5 0.0 0.1 0.0 2.7 0.0 7.0 0.9 0.2 0.0 0.3 0.0 0.5 0.0 0.3 3.0 1.1 4.0 0.6 0.1 0.9 2.9 0.0 0.1 0.0 0.1 1.0 0.1 18.4 0.0 0.0 1.3 0.6 0.1 3.0 0.0 3.5 1.2 0.3 0.9 0.0 1.6 19.3 9.0 3.0 0.1 1.2 0.0 6.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 3.3 12.3 7.0 6.7 1.3 48.0 10.4 49.9 0.0 0.7 3.5 2.4 0.0 0.0 2.0 1.2 14.7 1.1 0.8 0.6 0.2 2.3 0.8 1.4 4.3 0.2 0.0 0.0 0.1 0.0 1.1 0.0 0.2 4.1 0.2 0.2 19.0 1.8 5.3 5.3 0.0 0.9 15.6 0.0 0.3 0.0 1.5 34.6 0.8 0.1 0.0 0.7 0.0 0.0 6.1 19.1 9.6 75.8 0.4 7.2 0.0 0.0 7.4 0.0 2.0 0.5 0.4 1.5 229.9 0.0 0.5 0.2 0.1 0.2 0.3 0.0 5.7 20.7 1.5 3.8 1.6 9.7 0.1 0.8 7.5 0.1 0.4 DARS1 DARS ENSG00000115866 "Aspartyl-tRNA synthetase 1" P14868 2 135905881-135986100 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 85.1;Cytotrophoblasts: 115.4;Extravillous trophoblasts: 157.9;Hofbauer cells: 94.2;Syncytiotrophoblasts: 136.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020451, HPA029804, HPA029805" Enhanced Enhanced Cytosol NA NA 210000 "Cluster 30: Non-specific - Translation" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA020451: AB_1847479, HPA029804: AB_10599178, HPA029805: AB_10601994" "unprognostic (6.13e-2)" "unprognostic (8.16e-3)" "unprognostic (5.54e-2)" "unprognostic (5.36e-2)" "unprognostic (7.63e-2)" "unprognostic (1.91e-2)" "prognostic unfavorable (2.39e-6)" "unprognostic (2.98e-3)" "prognostic unfavorable (7.57e-4)" "unprognostic (6.00e-3)" "prognostic unfavorable (6.54e-4)" "unprognostic (2.78e-1)" "prognostic unfavorable (1.24e-5)" "unprognostic (1.04e-1)" "unprognostic (9.12e-2)" "unprognostic (3.94e-3)" "unprognostic (2.00e-1)" 37.5 42.1 30.1 41.2 31.2 34.0 48.7 33.3 52.1 34.7 28.0 38.5 23.5 38.4 22.8 46.0 37.8 25.8 42.3 29.5 35.2 47.3 44.2 27.8 48.3 32.6 31.2 47.2 36.1 38.4 24.6 44.4 35.6 33.6 26.6 87.1 32.5 36.5 82.8 40.2 28.0 39.3 34.0 32.3 33.3 17.8 30.7 63.1 43.4 60.1 55.4 40.0 36.4 35.3 201.6 77.0 73.4 66.3 61.0 78.1 141.6 99.8 92.6 92.2 91.1 163.0 84.0 210.0 159.8 78.4 86.6 111.7 94.9 114.9 170.3 95.6 86.0 134.0 76.8 185.6 83.9 188.3 90.8 84.5 75.6 109.1 99.8 122.9 46.8 106.3 131.6 66.0 66.6 87.3 139.2 117.4 77.8 85.3 66.9 179.3 157.9 139.0 91.8 76.9 40.3 89.6 75.0 63.5 74.8 72.2 66.8 118.2 38.2 86.0 87.4 64.5 92.8 194.9 123.3 250.2 144.1 132.3 51.0 33.7 85.4 51.2 115.2 82.6 174.7 219.9 172.6 151.4 133.7 198.8 175.2 154.2 31.7 171.9 67.4 130.4 168.9 153.3 30.1 31.2 33.3 52.1 29.5 35.2 32.6 31.2 35.6 34.0 30.7 35.3 29.4 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 85.1 0.0 0.0 0.0 0.0 115.4 20.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 157.9 18.2 0.0 0.0 0.0 0.0 0.0 0.0 94.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.0 0.0 136.4 4.4 0.0 0.0 0.0 DCAF12L1 "KIAA1892L, WDR40B" ENSG00000198889 "DDB1 and CUL4 associated factor 12 like 1" Q5VU92 X 126549383-126552814 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 4.9;testis: 6.2" "Group enriched" "Detected in some" 4 "Early spermatids: 20.7;Late spermatids: 44.4;Spermatogonia: 14.4" "Cancer enhanced" "Detected in some" "renal cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "EFO-21: 15.2;U-2 OS: 8.4" "HPA044737, HPA048981, HPA053138" Approved Uncertain Cytosol NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA044737: AB_2679067, HPA048981: AB_2680586, HPA053138: AB_2682054" "unprognostic (2.62e-5)" "unprognostic (2.88e-1)" "unprognostic (1.19e-1)" "unprognostic (3.40e-1)" "unprognostic (1.39e-3)" "unprognostic (1.34e-1)" "unprognostic (2.34e-1)" "unprognostic (1.74e-1)" 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 4.9 0.0 2.5 1.2 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 1.0 0.8 6.2 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 20.7 3.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.3 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.4 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.3 3.8 14.4 0.0 0.0 0.0 0.0 1.2 0.0 0.0 DCAF12L2 WDR40C ENSG00000198354 "DDB1 and CUL4 associated factor 12 like 2" Q5VW00 X 126163499-126166289 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.3;epididymis: 21.4" "Cell type enriched" "Detected in some" 7 "Granulosa cells: 11.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HAP1: 2.6;NTERA-2: 2.2;U-2 OS: 3.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA044737, HPA048981, HPA053138" Approved Uncertain Cytosol NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA044737: AB_2679067, HPA048981: AB_2680586, HPA053138: AB_2682054" "unprognostic (1.16e-4)" "unprognostic (8.83e-3)" "unprognostic (2.93e-1)" "unprognostic (2.52e-2)" "unprognostic (2.72e-1)" "unprognostic (3.02e-1)" "unprognostic (3.34e-3)" "unprognostic (1.16e-1)" "unprognostic (8.47e-4)" "unprognostic (1.56e-2)" "unprognostic (4.05e-2)" "unprognostic (3.86e-2)" "unprognostic (2.51e-1)" 0.8 0.9 1.9 0.0 2.0 0.0 0.4 0.1 2.2 1.4 0.0 0.7 0.0 2.4 21.4 0.1 2.3 0.1 0.0 2.5 3.5 0.2 0.0 0.0 0.1 9.3 1.5 1.4 0.0 2.5 1.3 0.0 4.2 1.5 0.0 0.2 0.3 4.3 0.1 0.2 0.2 1.3 1.6 0.0 0.3 5.5 3.1 0.0 0.1 0.9 0.2 1.2 0.5 1.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.0 0.1 2.2 2.5 3.5 9.3 1.5 4.2 1.6 3.1 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.7 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 DCBLD1 "dJ94G16.1, MGC46341" ENSG00000164465 "Discoidin, CUB and LCCL domain containing 1" Q8N8Z6 6 117453817-117569858 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA059667 Approved Approved Cytosol NA NA 22000000 "Cluster 32: T-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA059667: AB_2684099" "unprognostic (1.00e-1)" "prognostic unfavorable (6.44e-5)" "unprognostic (1.08e-1)" "unprognostic (3.23e-3)" "unprognostic (2.47e-1)" "unprognostic (2.29e-3)" "unprognostic (1.53e-2)" "unprognostic (5.94e-3)" "unprognostic (3.74e-2)" "unprognostic (8.99e-2)" "unprognostic (5.69e-3)" "unprognostic (6.33e-2)" "prognostic unfavorable (8.57e-8)" "unprognostic (6.99e-2)" "unprognostic (4.72e-2)" "unprognostic (7.44e-2)" "unprognostic (1.36e-1)" 8.3 3.5 3.7 6.0 4.6 0.6 5.7 3.5 4.9 9.1 2.6 6.6 6.5 5.1 3.3 5.4 2.5 9.1 6.0 5.5 2.7 4.8 9.6 9.9 3.4 3.5 3.6 1.9 6.3 6.8 8.3 8.7 3.7 2.6 6.1 1.0 4.8 2.8 5.5 2.9 8.1 3.8 3.4 3.8 7.6 5.6 3.0 1.2 5.9 5.1 2.5 6.3 5.8 4.3 8.0 17.9 6.3 7.0 10.8 13.5 17.9 45.1 58.1 36.9 27.8 37.9 16.7 0.0 21.8 19.1 45.9 17.9 12.1 19.9 38.7 3.5 9.4 6.8 18.5 62.3 46.7 10.0 5.7 15.4 45.5 33.6 31.4 42.5 52.3 6.7 14.8 6.7 48.9 6.4 0.1 6.7 4.7 21.4 7.4 0.0 1.3 4.7 8.2 9.4 19.0 0.3 33.0 3.6 5.3 9.0 4.7 13.1 38.9 0.0 44.1 12.6 19.8 18.9 5.4 5.3 18.7 9.6 16.5 0.0 0.2 0.0 0.6 0.2 0.1 0.0 0.8 1.2 0.2 0.0 1.0 1.3 0.0 0.4 0.1 0.4 0.9 0.5 3.7 4.6 3.5 4.9 5.5 2.7 3.5 3.6 3.7 3.4 3.0 4.3 16.0 16.0 18.8 5.2 3.0 5.2 3.7 12.3 0.6 8.4 4.8 3.6 5.3 12.8 14.4 5.5 6.2 31.5 4.9 9.5 1.9 7.0 33.0 5.3 15.1 11.0 4.2 3.2 20.8 4.8 6.1 6.6 13.7 7.9 1.3 13.9 17.2 9.6 5.8 5.0 3.3 8.5 6.1 7.0 15.0 10.9 0.9 5.8 8.8 13.1 2.5 1.1 6.2 12.1 11.6 10.4 7.7 0.4 1.6 3.0 11.1 2.7 5.7 3.5 13.1 5.1 27.6 2.2 10.6 6.8 6.0 18.2 5.1 2.1 11.1 5.4 DCX "DBCN, DC, LISX, SCLH, XLIS" ENSG00000077279 Doublecortin O43602 X 111293779-111412429 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Disease variant, Epilepsy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.7;endometrium 1: 1.4;retina: 2.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 39.1;Inhibitory neurons: 90.2;Oligodendrocyte precursor cells: 49.8;Rod photoreceptor cells: 21.8" "Cancer enriched" "Detected in some" 5 "glioma: 5.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "SCLC-21H: 52.5;SH-SY5Y: 22.1" "Region enriched" "Detected in many" 9 "olfactory bulb: 74.0" "Region enriched" "Detected in all" 4 "olfactory bulb: 68.6" HPA036121 Enhanced Supported Approved Cytosol NA NA "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA036121: AB_2674950" "unprognostic (1.36e-2)" "unprognostic (1.99e-1)" "unprognostic (7.36e-2)" "unprognostic (4.00e-2)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (2.00e-2)" "unprognostic (7.18e-2)" "unprognostic (3.24e-2)" "unprognostic (2.33e-3)" "unprognostic (3.67e-1)" "unprognostic (4.90e-4)" "unprognostic (5.02e-3)" "unprognostic (1.27e-1)" "unprognostic (1.85e-1)" 0.1 0.2 2.1 0.0 2.4 0.0 1.3 0.0 2.5 0.1 0.0 0.0 0.0 1.4 1.2 0.0 0.0 0.1 0.0 1.4 2.7 0.0 0.0 0.0 0.0 0.2 1.3 0.0 0.1 0.0 0.3 0.0 0.8 0.0 0.0 2.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.9 0.0 0.0 0.0 52.5 22.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.4 0.0 2.5 1.4 2.7 0.2 1.3 0.8 0.0 2.4 0.5 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 2.5 1.6 2.2 0.7 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 39.1 0.0 0.2 6.8 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 90.2 0.2 0.0 0.0 0.4 0.5 0.0 0.0 1.8 1.9 0.0 1.6 0.0 49.8 2.3 0.1 0.0 1.5 0.0 0.0 0.0 0.1 0.0 21.8 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 10.2 0.0 0.0 DDIT4 "Dig2, FLJ20500, REDD-1, REDD1, RTP801" ENSG00000168209 "DNA damage inducible transcript 4" Q9NX09 10 72273919-72276036 "Predicted intracellular proteins" "Antiviral defense, Apoptosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 776.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 657.6;hTCEpi: 2252.5;hTERT-HME1: 877.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034507, HPA034508" Approved Supported Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "HPA034507: AB_2674199, HPA034508: AB_10601206" "unprognostic (2.84e-3)" "unprognostic (1.05e-3)" "unprognostic (1.06e-1)" "unprognostic (2.59e-1)" "unprognostic (7.91e-3)" "prognostic unfavorable (5.42e-4)" "unprognostic (7.65e-2)" "unprognostic (1.62e-3)" "unprognostic (2.90e-1)" "unprognostic (4.96e-3)" "prognostic unfavorable (2.78e-4)" "unprognostic (9.72e-2)" "prognostic unfavorable (2.54e-6)" "unprognostic (8.52e-2)" "unprognostic (1.12e-1)" "unprognostic (5.92e-2)" "unprognostic (1.66e-1)" 313.5 280.9 88.9 83.7 89.3 123.7 287.3 92.5 106.4 415.9 103.4 93.5 20.8 98.6 12.6 425.0 118.6 47.8 237.2 82.4 87.7 179.9 337.1 197.8 90.1 102.9 92.0 741.5 675.4 94.4 169.5 51.8 90.0 171.1 13.3 86.7 224.9 68.3 278.1 231.6 111.7 25.4 88.0 166.3 121.2 32.0 95.8 102.5 105.1 60.0 114.3 315.3 597.5 98.2 139.2 95.2 20.0 179.3 124.0 74.3 52.1 40.3 45.6 13.5 56.7 11.1 280.5 14.3 113.7 6.5 19.1 143.0 28.9 657.6 33.7 213.9 35.8 15.1 115.4 74.0 501.2 47.7 57.7 291.1 2252.5 59.2 877.9 127.1 60.1 33.9 135.3 347.2 51.5 58.7 28.5 62.1 4.2 67.6 22.2 15.2 22.4 265.7 115.9 30.9 33.2 46.2 98.3 152.0 583.9 43.0 20.9 104.4 118.7 4.6 35.4 8.7 22.3 234.3 135.1 42.3 252.9 99.9 29.8 68.8 7.6 51.1 236.4 14.5 249.6 97.4 163.8 141.3 40.3 122.4 274.5 213.7 17.1 408.1 13.0 197.4 136.9 215.0 88.9 89.3 92.5 106.4 82.4 87.7 102.9 92.0 90.0 88.0 95.8 98.2 366.5 12.8 27.1 136.1 290.6 228.5 383.5 534.1 290.8 87.8 129.8 112.5 16.1 77.2 226.6 60.7 79.2 9.9 680.2 109.2 60.7 310.7 3.1 46.4 101.8 177.9 75.1 129.0 2.1 165.3 141.1 203.8 116.2 69.2 415.0 30.8 249.1 83.8 89.7 30.3 3.8 105.6 173.0 102.4 485.9 7.0 88.3 280.5 396.6 5.6 38.9 682.8 249.3 7.1 5.5 131.5 177.7 128.2 776.1 143.5 41.6 19.3 100.6 143.3 72.3 124.2 338.3 2.1 5.7 519.6 251.5 19.0 537.4 126.0 70.6 359.6 DDO ENSG00000203797 "D-aspartate oxidase" Q99489 6 110391771-110415575 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 18.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 17.4;Muller glia cells: 8.2;Oligodendrocytes: 13.3;Paneth cells: 8.5;Proximal enterocytes: 8.5;Proximal tubular cells: 12.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 3.3;myeloid DC: 4.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "GAMG: 11.5;RPMI-8226: 15.9;U-937: 17.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037525, HPA037526" Enhanced Enhanced Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "HPA037525: AB_2675523, HPA037526: AB_10672352" "unprognostic (1.37e-1)" "unprognostic (1.54e-1)" "unprognostic (6.51e-2)" "unprognostic (1.30e-2)" "unprognostic (2.00e-1)" "unprognostic (3.28e-2)" "unprognostic (3.71e-2)" "unprognostic (1.01e-2)" "unprognostic (2.05e-1)" "unprognostic (2.91e-1)" "unprognostic (6.97e-2)" "unprognostic (1.43e-1)" "prognostic favorable (8.69e-5)" "unprognostic (3.51e-4)" "unprognostic (3.36e-3)" "unprognostic (1.27e-3)" "unprognostic (9.06e-2)" 1.9 8.2 4.5 0.8 7.0 1.4 2.5 5.0 4.8 1.9 4.3 2.3 7.4 2.1 2.7 0.8 4.9 2.9 18.4 4.4 4.5 10.6 11.1 3.2 1.0 5.4 4.9 0.3 2.6 5.3 1.2 1.6 5.3 2.0 3.2 2.4 4.2 2.3 10.9 0.4 7.0 2.2 4.8 2.1 1.1 0.1 4.7 0.4 1.3 7.4 0.2 1.6 0.9 5.9 0.2 0.0 0.0 0.1 0.0 0.2 1.1 0.1 5.4 1.3 0.9 0.0 0.1 0.0 0.7 0.7 11.5 0.0 0.0 0.0 2.3 5.0 0.0 5.1 0.1 4.3 1.6 0.0 0.0 0.1 0.0 2.7 0.1 2.3 0.0 0.0 0.0 1.9 4.5 0.0 0.0 0.2 0.0 0.0 0.1 0.1 3.0 15.9 0.0 4.9 0.1 0.2 0.0 0.5 0.6 0.0 0.7 1.1 0.9 1.0 0.1 0.0 2.6 0.1 0.4 0.0 2.0 17.4 0.0 0.0 2.9 0.0 0.0 3.3 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 1.1 1.0 0.0 0.0 1.1 4.5 7.0 5.0 4.8 4.4 4.5 5.4 4.9 5.3 4.8 4.7 5.9 1.1 0.0 0.0 4.9 0.0 0.0 0.7 0.7 0.6 0.0 1.4 1.1 17.4 0.0 0.4 0.0 2.1 0.2 0.1 1.8 3.9 4.5 0.3 3.6 0.5 0.7 4.2 0.0 0.0 2.2 0.2 0.6 0.0 0.9 0.0 0.1 2.5 4.9 1.7 0.0 0.1 6.0 0.0 3.1 0.4 0.0 0.3 1.6 0.0 0.0 2.0 8.2 0.0 3.5 13.3 0.8 8.5 0.0 0.0 0.4 8.5 12.9 2.2 0.2 0.0 2.1 1.2 0.0 0.0 0.2 0.0 0.0 0.2 0.3 5.0 0.5 DENR "DRP, DRP1, SMAP-3" ENSG00000139726 "Density regulated re-initiation and release factor" O43583 12 122752824-122771064 "Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 227.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021783 Approved Approved Cytosol NA NA 200000 "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA021783: AB_2670820" "unprognostic (3.65e-2)" "unprognostic (7.00e-2)" "unprognostic (5.69e-2)" "unprognostic (7.33e-3)" "unprognostic (6.62e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (1.58e-7)" "unprognostic (2.23e-3)" "unprognostic (2.13e-2)" "unprognostic (2.11e-2)" "unprognostic (3.75e-1)" "unprognostic (1.02e-3)" "prognostic unfavorable (8.57e-6)" "unprognostic (1.32e-1)" "unprognostic (1.26e-1)" "unprognostic (2.65e-1)" "unprognostic (1.35e-1)" 25.4 22.6 19.0 27.0 19.6 27.5 29.6 15.3 23.6 22.2 15.1 25.5 26.7 23.7 22.1 32.5 21.7 22.1 24.4 19.4 20.2 25.5 27.6 18.8 36.2 16.8 21.6 19.2 21.2 59.0 17.1 31.6 19.5 28.0 26.0 16.5 28.4 24.8 60.2 29.6 25.0 24.5 15.2 28.0 23.3 14.6 18.9 38.9 29.8 44.7 35.5 30.0 20.4 16.7 113.1 62.1 77.7 80.1 48.7 71.9 67.6 100.5 56.1 87.6 60.6 86.9 40.6 99.9 103.4 72.5 66.6 84.0 93.8 89.5 117.6 90.9 67.3 122.8 36.2 63.8 63.5 139.6 97.4 62.8 86.9 79.3 107.4 81.6 86.4 109.7 129.8 35.8 94.8 74.9 137.7 134.1 159.2 67.2 128.4 120.6 91.2 63.7 85.3 99.9 89.3 63.4 139.2 40.8 107.3 79.1 129.5 78.1 82.2 81.2 95.9 91.7 102.1 58.8 145.8 160.4 76.4 100.1 90.9 227.9 35.0 58.1 38.8 53.3 45.3 45.5 41.9 39.4 47.3 41.4 48.5 43.4 42.2 47.3 69.9 42.1 49.2 44.5 19.0 19.6 15.3 23.6 19.4 20.2 16.8 21.6 19.5 15.2 18.9 16.7 43.4 70.5 40.1 31.0 59.8 71.9 65.9 55.4 59.7 37.7 66.2 69.8 66.3 45.8 47.7 47.8 41.7 73.0 60.8 40.9 64.6 68.6 17.9 67.7 83.5 51.4 84.8 53.8 39.0 61.8 130.3 48.3 40.8 70.7 43.1 50.4 42.1 54.3 57.4 55.5 36.2 53.6 44.7 50.1 42.4 8.0 50.4 49.3 26.6 25.3 60.2 47.3 75.2 48.2 31.3 88.0 44.6 45.9 47.9 73.2 40.3 67.3 49.5 35.9 19.7 46.2 62.5 120.3 136.8 72.8 64.9 60.6 54.7 47.3 58.8 51.3 DGKD "DGKdelta, KIAA0145" ENSG00000077044 "Diacylglycerol kinase delta" Q16760 2 233354494-233472104 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 30.4" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 143.2;Inhibitory neurons: 137.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 17.3;HeLa: 21.8;U-698: 22.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027530, HPA049101" Approved Supported Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA027530: AB_2672320, HPA049101: AB_2680630" "unprognostic (1.84e-1)" "unprognostic (2.19e-2)" "unprognostic (7.76e-3)" "unprognostic (1.92e-2)" "unprognostic (5.69e-2)" "unprognostic (6.24e-2)" "prognostic unfavorable (1.69e-5)" "unprognostic (2.25e-1)" "unprognostic (1.17e-3)" "unprognostic (6.03e-2)" "unprognostic (5.76e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (4.07e-8)" "unprognostic (1.78e-1)" "unprognostic (7.18e-2)" "unprognostic (1.22e-1)" "unprognostic (5.94e-3)" 5.2 3.4 4.3 1.9 5.5 12.0 5.9 20.5 6.2 4.5 3.2 9.0 1.6 5.9 1.6 2.2 5.7 1.0 7.6 5.8 4.0 2.5 3.6 10.6 4.3 6.5 3.9 8.9 2.7 0.4 3.7 2.9 7.4 5.7 2.3 5.4 5.9 0.5 30.4 3.0 12.9 0.7 4.1 11.4 25.2 9.6 4.4 1.0 8.3 0.9 4.5 5.3 2.6 8.8 1.7 8.5 2.1 1.5 1.5 1.4 3.0 2.4 1.0 0.6 0.5 9.7 1.9 10.3 1.1 2.4 4.5 2.0 2.4 1.0 3.2 17.3 11.3 4.7 21.8 5.8 0.9 11.7 7.2 2.3 2.2 1.1 2.1 1.8 0.8 2.1 7.8 1.8 1.6 3.1 9.2 3.3 1.6 2.8 6.9 14.5 5.7 1.6 0.9 3.3 2.1 2.2 1.4 2.3 1.0 1.8 0.6 5.2 1.0 1.2 3.0 1.2 1.7 7.1 6.2 22.7 0.8 5.6 0.6 1.7 1.6 5.6 2.1 0.6 1.1 4.8 0.5 1.5 0.4 5.0 1.7 2.4 1.2 0.6 1.0 0.4 0.2 1.7 4.3 5.5 20.5 6.2 5.8 4.0 6.5 3.9 7.4 4.1 4.4 8.8 18.9 32.1 46.2 27.1 61.1 8.9 6.4 5.6 4.6 33.8 19.6 11.6 21.0 0.0 13.8 0.0 62.6 14.6 62.0 40.6 0.0 3.6 14.9 23.4 12.5 19.1 2.4 5.0 11.1 4.4 1.2 9.7 143.2 38.1 5.7 13.1 4.6 7.0 6.8 8.4 137.9 32.8 8.2 10.4 13.8 38.7 6.5 28.7 8.8 11.2 17.5 13.9 49.4 43.2 81.5 26.0 13.5 4.5 34.7 17.6 29.6 2.6 4.8 44.3 19.7 49.4 21.2 14.4 29.3 4.5 3.7 2.5 32.5 7.6 20.1 9.9 DGLUCY "C14orf159, FLJ39975" ENSG00000133943 "D-glutamate cyclase" Q7Z3D6 14 91060333-91225632 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 163.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 28.9;Collecting duct cells: 29.5;Cytotrophoblasts: 30.9;Endometrial ciliated cells: 29.4;Granulosa cells: 49.8;Hofbauer cells: 31.7;Theca cells: 35.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 200.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041423, HPA052932" Approved Supported Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA041423: AB_10795540, HPA052932: AB_2681991" "unprognostic (5.02e-2)" "unprognostic (1.01e-2)" "unprognostic (1.56e-1)" "prognostic favorable (4.28e-4)" "unprognostic (1.28e-1)" "unprognostic (2.26e-1)" "unprognostic (3.58e-2)" "prognostic favorable (9.48e-5)" "unprognostic (3.56e-1)" "prognostic favorable (7.28e-4)" "unprognostic (2.30e-1)" "unprognostic (1.74e-1)" "prognostic favorable (3.77e-15)" "unprognostic (1.50e-1)" "unprognostic (9.51e-2)" "unprognostic (2.75e-2)" "unprognostic (2.57e-3)" 23.9 32.2 38.5 21.4 46.0 21.7 16.7 53.5 49.2 25.0 76.1 33.5 25.1 26.0 17.2 28.4 38.6 22.6 122.3 36.6 39.8 35.6 24.9 25.0 21.6 45.5 51.3 22.9 16.8 47.9 21.5 16.6 42.1 22.8 30.4 8.3 32.2 34.1 143.0 25.6 23.7 32.0 38.0 33.6 38.1 19.0 45.4 27.3 30.1 163.6 19.9 31.9 20.2 45.2 6.2 16.4 8.0 20.1 32.8 30.6 21.0 6.6 17.7 19.3 19.6 10.9 46.7 41.3 46.0 18.8 24.9 18.0 23.0 24.7 7.9 22.8 9.5 27.7 9.1 13.8 47.8 28.5 38.2 47.5 10.5 10.6 4.0 25.3 34.6 22.8 14.0 54.4 18.4 1.4 22.7 27.0 16.4 0.8 1.4 38.2 15.7 30.9 32.7 25.9 22.4 11.2 10.4 17.8 7.3 8.4 32.0 24.5 24.7 5.7 4.8 17.1 5.9 30.9 23.8 14.0 29.6 36.8 3.8 67.5 48.8 30.8 30.1 69.4 30.3 34.0 19.3 24.5 72.9 22.4 15.9 20.0 200.5 21.0 60.7 22.0 45.2 29.0 38.5 46.0 53.5 49.2 36.6 39.8 45.5 51.3 42.1 38.0 45.4 45.2 19.2 28.9 16.4 0.0 4.3 0.0 0.0 0.0 0.0 0.0 11.5 13.2 0.0 0.0 5.6 29.5 0.0 30.9 12.5 0.0 21.5 17.6 0.0 29.4 14.8 6.2 0.0 0.0 0.0 5.8 15.8 7.4 0.0 25.0 7.6 49.8 0.0 0.0 31.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 7.2 0.0 0.0 0.0 0.0 6.3 0.0 0.0 2.7 0.0 0.0 17.0 5.1 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 16.8 8.7 35.6 0.0 0.0 DHX29 DDX29 ENSG00000067248 "DExH-box helicase 29" Q7Z478 5 55256055-55307694 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Helicase, Hydrolase, Initiation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038317, HPA038318" Approved Approved Cytosol "Intracellular and membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA038317: AB_10673169, HPA038318: AB_10672589" "unprognostic (3.43e-2)" "unprognostic (5.09e-1)" "unprognostic (2.21e-2)" "unprognostic (1.19e-1)" "unprognostic (1.17e-1)" "unprognostic (2.80e-1)" "unprognostic (2.37e-3)" "unprognostic (1.72e-1)" "unprognostic (6.66e-2)" "unprognostic (1.76e-2)" "unprognostic (3.79e-2)" "unprognostic (1.30e-1)" "unprognostic (4.57e-3)" "unprognostic (4.01e-1)" "unprognostic (3.85e-1)" "unprognostic (4.78e-3)" "unprognostic (9.40e-2)" 10.6 10.6 5.3 9.7 5.7 6.7 12.0 9.1 7.0 12.5 6.7 12.1 7.2 11.4 6.8 12.7 9.5 8.9 10.7 5.7 5.1 16.9 13.1 9.4 9.5 5.0 5.0 8.9 11.7 18.7 10.4 11.4 5.1 13.4 9.8 8.7 10.3 12.0 24.2 11.6 8.4 12.6 5.5 7.9 10.4 7.4 5.1 10.0 15.4 14.8 9.7 12.0 10.3 7.1 36.7 25.5 20.9 27.2 32.3 28.2 25.6 38.9 30.9 28.2 28.7 21.3 23.0 20.7 34.9 44.5 35.8 26.0 34.0 37.1 40.5 9.1 19.4 18.8 21.6 14.6 18.3 13.3 19.6 23.8 23.0 29.9 17.2 18.5 37.9 16.5 24.4 15.0 33.4 25.9 21.4 11.1 17.5 10.5 27.1 10.9 31.8 35.7 23.0 25.3 19.6 12.5 37.4 21.3 18.6 20.5 28.7 21.7 32.9 25.9 20.2 22.8 27.4 13.2 24.1 29.0 29.9 23.0 29.1 68.6 22.5 24.3 18.0 24.4 20.4 27.3 22.5 20.0 17.5 26.3 25.0 21.6 20.6 24.5 30.1 36.8 21.9 8.9 5.3 5.7 9.1 7.0 5.7 5.1 5.0 5.0 5.1 5.5 5.1 7.1 44.5 70.5 42.6 34.0 35.2 37.6 37.5 71.8 39.3 81.6 44.9 49.8 73.6 41.5 69.4 64.4 41.7 68.3 39.5 34.4 54.8 61.4 54.8 37.4 61.5 40.7 38.4 68.4 47.3 61.7 54.6 52.7 35.7 36.5 31.6 39.0 22.9 45.0 41.2 42.1 46.9 36.4 63.1 26.0 26.6 16.6 46.6 41.5 28.4 28.1 50.7 35.7 35.0 42.7 54.9 61.9 27.3 53.0 57.0 53.2 35.2 105.2 35.9 83.6 52.6 52.8 54.2 117.5 108.1 50.1 47.5 81.3 36.1 106.4 39.9 43.3 DICER1 "Dicer, HERNA, K12H4.8-LIKE, KIAA0928, MNG1" ENSG00000100697 "Dicer 1, ribonuclease III" Q9UPY3 14 95086228-95158010 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, RNA-mediated gene silencing" "Endonuclease, Helicase, Hydrolase, Nuclease, RNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 418.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000694, CAB068185" Approved Supported Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "CAB068185: AB_2665650, HPA000694: AB_1078661" "unprognostic (2.97e-1)" "unprognostic (2.70e-2)" "unprognostic (1.21e-1)" "unprognostic (1.72e-1)" "unprognostic (6.75e-2)" "unprognostic (9.62e-2)" "unprognostic (1.96e-2)" "unprognostic (7.73e-2)" "unprognostic (1.21e-1)" "unprognostic (8.52e-3)" "unprognostic (5.73e-2)" "unprognostic (9.22e-2)" "unprognostic (4.22e-2)" "unprognostic (9.07e-2)" "unprognostic (2.58e-1)" "unprognostic (6.04e-3)" "unprognostic (3.74e-2)" 15.6 7.9 6.7 14.0 22.5 10.8 15.1 12.3 11.4 13.3 7.4 13.0 7.5 12.7 8.3 15.0 12.4 8.7 9.9 7.2 14.0 10.7 12.8 14.9 11.0 19.1 16.0 14.3 12.6 11.5 10.6 18.7 18.5 12.5 10.9 19.3 12.4 10.1 19.2 13.0 11.6 11.5 11.6 12.1 10.1 13.2 20.3 8.5 14.7 16.2 12.0 12.7 14.5 39.4 18.6 19.4 40.7 12.0 7.2 14.5 26.4 15.5 10.7 11.3 11.1 25.4 12.5 20.9 16.1 16.0 10.4 21.2 31.6 13.9 20.5 35.9 14.6 36.5 10.1 16.0 6.7 22.6 18.0 12.2 10.1 12.3 20.8 8.0 16.1 15.7 15.7 16.6 16.9 21.8 24.1 6.8 9.3 11.0 10.2 16.0 31.9 12.2 8.2 30.9 31.9 16.4 16.2 13.4 15.2 19.2 18.0 12.4 16.4 8.1 14.4 14.0 16.9 18.9 31.7 31.4 8.0 14.5 13.1 1.4 1.1 0.8 0.3 1.4 0.7 0.7 0.6 0.4 0.8 0.7 0.5 0.3 3.9 0.5 3.2 0.4 0.7 0.4 6.7 22.5 12.3 11.4 7.2 14.0 19.1 16.0 18.5 11.6 20.3 39.4 69.4 54.5 53.7 88.8 45.7 27.4 49.5 29.9 40.5 98.2 50.7 29.1 36.4 41.5 47.3 46.0 56.3 46.6 36.9 44.0 5.9 33.4 23.3 37.4 54.2 52.0 46.1 33.4 99.7 23.1 22.8 45.6 33.1 50.1 12.0 35.5 42.1 60.1 48.8 107.7 112.2 29.7 24.4 104.2 24.8 15.5 54.3 82.3 23.2 81.5 84.6 33.5 33.0 109.1 418.6 33.2 28.0 52.6 39.2 62.5 27.1 25.9 38.6 73.8 32.9 64.3 41.9 45.5 56.1 63.0 27.6 25.7 31.7 35.9 33.9 62.1 DIXDC1 "Dixin, KIAA1735" ENSG00000150764 "DIX domain containing 1" Q155Q3 11 111927144-112022653 "Predicted intracellular proteins" "Wnt signaling pathway" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 104.3;Horizontal cells: 121.1;Oligodendrocytes: 140.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "eosinophil: 5.2" "Lineage enriched" "Detected in single" 11 "granulocytes: 5.2" "Cell line enhanced" "Detected in many" "hTERT-HME1: 42.7;TIME: 50.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039424, HPA039658, HPA061366" Approved Supported Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "HPA039424: AB_2676500, HPA039658: AB_2676611, HPA061366: " "unprognostic (1.93e-1)" "unprognostic (2.90e-2)" "unprognostic (8.93e-3)" "unprognostic (2.84e-1)" "unprognostic (2.98e-2)" "unprognostic (1.44e-1)" "unprognostic (2.37e-1)" "unprognostic (1.41e-1)" "unprognostic (7.23e-2)" "unprognostic (1.59e-1)" "unprognostic (7.85e-2)" "unprognostic (5.11e-2)" "prognostic favorable (6.89e-5)" "unprognostic (4.10e-2)" "unprognostic (2.11e-1)" "unprognostic (2.52e-2)" "prognostic unfavorable (4.19e-5)" 17.8 17.7 16.4 8.6 23.2 0.7 15.0 36.8 22.6 18.7 22.8 29.5 5.6 24.8 18.6 12.7 20.4 12.6 23.3 17.0 16.9 11.4 7.0 9.4 2.6 20.1 21.8 15.8 3.8 17.1 7.1 10.8 19.1 23.4 10.0 22.0 7.8 35.8 13.7 5.4 9.1 25.6 18.0 2.9 14.9 19.1 19.7 2.6 10.7 12.3 2.5 25.3 12.0 34.4 0.8 3.7 9.9 18.5 29.9 17.5 2.1 7.7 5.3 2.9 5.2 0.6 2.0 1.6 2.0 21.5 3.4 0.9 4.4 2.4 2.9 6.4 3.7 0.8 5.8 10.3 4.6 5.3 0.7 14.2 19.3 6.3 42.7 21.5 30.6 4.0 5.2 0.6 11.9 0.9 3.3 4.6 5.9 0.8 6.6 1.6 2.9 6.1 12.1 0.3 8.0 16.7 5.7 4.6 2.5 4.3 6.8 2.0 50.4 13.1 5.6 2.4 12.9 1.2 5.5 0.8 7.2 13.5 4.7 0.0 0.1 5.2 0.3 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.4 0.4 0.4 0.0 0.0 0.0 0.0 0.1 16.4 23.2 36.8 22.6 17.0 16.9 20.1 21.8 19.1 18.0 19.7 34.4 12.8 16.0 10.3 40.1 0.4 6.4 16.3 4.1 11.4 22.3 23.7 28.8 35.6 7.2 10.1 18.4 104.3 1.4 0.9 2.6 15.6 6.4 23.1 32.1 48.6 28.1 2.4 2.1 47.7 7.7 5.1 32.8 11.7 11.3 1.3 6.3 62.8 19.3 1.7 121.1 83.8 13.9 6.1 3.4 5.3 17.5 39.7 1.5 12.4 20.6 1.0 30.2 0.0 34.7 140.4 7.0 6.2 36.9 2.0 10.8 2.7 15.4 35.5 69.2 13.1 25.3 31.8 62.3 16.4 3.3 4.1 1.4 2.0 3.5 4.5 3.1 DLEC1 "CFAP81, DLC1, FAP81" ENSG00000008226 "DLEC1 cilia and flagella associated protein" Q9Y238 3 38039205-38124025 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 14.7;fallopian tube: 27.9;testis: 13.2" "Group enriched" "Detected in many" 4 "Endometrial ciliated cells: 45.0;Respiratory ciliated cells: 74.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA019077 Enhanced Supported Cytosol NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA019077: AB_1847724" "unprognostic (1.24e-4)" "unprognostic (3.60e-3)" "unprognostic (2.11e-1)" "unprognostic (1.09e-3)" "unprognostic (2.32e-1)" "unprognostic (1.76e-3)" "unprognostic (2.50e-3)" "unprognostic (8.54e-3)" "unprognostic (1.37e-1)" "unprognostic (1.69e-1)" "unprognostic (9.53e-2)" "unprognostic (7.62e-2)" "unprognostic (8.70e-4)" "unprognostic (1.77e-1)" "unprognostic (1.45e-1)" "unprognostic (2.89e-2)" "unprognostic (1.94e-4)" 1.2 0.3 2.3 0.3 2.1 0.9 0.4 1.6 1.2 3.5 14.7 0.3 0.4 0.5 4.1 0.1 27.9 0.6 0.2 2.5 2.9 0.3 0.1 4.8 0.4 6.6 8.6 0.9 0.1 0.1 9.6 0.1 4.7 0.9 0.4 0.0 0.9 0.5 0.0 0.4 0.4 0.1 5.3 0.5 0.3 13.2 3.2 0.1 1.1 0.0 0.3 0.2 0.1 2.5 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.3 2.1 1.6 1.2 2.5 2.9 6.6 8.6 4.7 5.3 3.2 2.5 0.0 3.2 3.0 2.9 0.4 0.5 0.5 3.0 1.2 1.2 0.4 0.4 0.7 0.0 14.1 0.0 0.0 0.1 0.4 1.2 0.0 0.1 4.5 45.0 1.2 0.6 1.2 0.8 1.1 0.2 0.1 1.3 0.0 1.4 2.5 0.2 0.0 0.3 0.5 0.0 0.9 0.7 6.1 0.6 1.2 6.6 0.9 1.1 0.0 2.8 0.8 0.2 2.1 0.5 0.3 0.1 1.4 0.0 2.8 0.5 0.7 0.5 74.4 0.8 0.0 0.7 1.5 6.7 1.3 1.0 0.3 0.1 1.3 0.4 0.2 0.4 DNAAF2 "C14orf104, CILD10, FLJ10563, KTU, PF13" ENSG00000165506 "Dynein axonemal assembly factor 2" Q9NVR5 14 49625174-49635244 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002894, HPA004113" Enhanced Supported Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 57: B-cells - Immune response" Cytosol "HPA002894: AB_1078316, HPA004113: AB_1078315" "unprognostic (3.88e-2)" "unprognostic (2.11e-1)" "unprognostic (7.57e-2)" "unprognostic (5.85e-2)" "unprognostic (1.19e-2)" "unprognostic (1.65e-1)" "unprognostic (9.50e-2)" "unprognostic (1.75e-2)" "unprognostic (2.53e-2)" "unprognostic (2.47e-1)" "unprognostic (4.51e-2)" "unprognostic (2.25e-2)" "prognostic favorable (6.74e-7)" "unprognostic (6.72e-2)" "unprognostic (2.54e-1)" "unprognostic (5.04e-2)" "unprognostic (3.44e-2)" 3.8 4.6 3.2 4.4 3.1 3.4 5.7 3.8 3.3 4.3 6.0 5.4 7.6 4.0 4.1 4.4 8.6 3.7 4.3 3.0 3.5 6.8 9.3 3.7 5.5 3.5 4.3 3.5 6.9 3.9 3.4 3.4 3.5 4.0 4.7 4.8 5.5 3.0 5.0 3.2 6.2 3.3 3.6 4.1 5.1 6.3 3.4 4.7 5.3 5.3 4.6 4.6 3.3 3.6 14.2 8.3 18.0 14.1 8.6 9.9 17.1 7.5 8.3 8.2 9.0 8.1 13.4 20.7 11.6 5.0 6.7 15.3 15.0 10.6 10.2 14.6 8.9 10.6 6.2 14.1 6.7 17.3 8.6 6.6 11.3 7.0 9.5 8.4 8.5 11.3 16.0 13.8 8.2 17.7 11.4 17.8 19.6 14.7 15.1 14.0 13.9 7.0 11.7 11.8 27.4 20.4 11.2 12.0 13.8 11.3 13.7 6.9 7.0 7.6 21.7 7.9 9.5 27.5 18.4 17.1 2.9 10.5 8.5 7.8 4.9 6.8 7.4 4.5 8.9 11.6 8.2 9.9 5.7 9.3 7.9 7.8 1.8 12.4 5.8 5.1 8.5 4.8 3.2 3.1 3.8 3.3 3.0 3.5 3.5 4.3 3.5 3.6 3.4 3.6 9.8 3.2 5.6 5.9 38.5 41.0 25.0 38.9 41.5 7.0 21.4 20.3 10.6 15.7 14.6 12.9 0.0 21.6 16.2 13.0 31.3 28.4 25.9 30.3 22.9 17.1 9.6 13.9 6.8 24.0 29.4 17.6 19.4 13.8 12.0 12.2 19.2 26.6 14.0 3.3 8.0 15.3 48.8 9.2 21.1 7.5 18.3 10.2 19.6 2.8 10.5 11.3 19.6 6.6 6.2 25.7 13.0 16.6 43.7 36.2 30.8 37.9 27.2 11.9 6.6 16.0 15.4 22.4 17.9 38.6 44.0 12.4 28.0 30.2 22.8 20.0 DNAH7 KIAA0944 ENSG00000118997 "Dynein axonemal heavy chain 7" Q8WXX0 2 195737703-196068837 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.9;choroid plexus: 29.8" "Cell type enhanced" "Detected in many" "Astrocytes: 197.2;Cone photoreceptor cells: 70.9;Early spermatids: 59.3;Endometrial ciliated cells: 103.5;Excitatory neurons: 93.0;Respiratory ciliated cells: 139.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "PC-3: 5.9;RPTEC TERT1: 2.8" "Region enhanced" "Detected in many" "midbrain: 4.4" "HPA034724, HPA044070" Enhanced Supported Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA034724: AB_10670977, HPA044070: AB_2678798" "unprognostic (1.71e-1)" "unprognostic (2.81e-2)" "unprognostic (2.65e-2)" "unprognostic (1.04e-2)" "unprognostic (3.56e-1)" "unprognostic (1.58e-2)" "unprognostic (6.74e-3)" "unprognostic (2.24e-1)" "unprognostic (1.71e-1)" "unprognostic (1.63e-1)" "unprognostic (2.84e-2)" "unprognostic (1.71e-1)" "unprognostic (6.25e-3)" "unprognostic (2.24e-1)" "unprognostic (7.76e-2)" "unprognostic (2.52e-3)" "unprognostic (3.98e-2)" 0.3 1.0 8.2 0.2 7.9 0.0 0.6 3.6 10.1 2.5 29.8 0.7 0.1 0.8 1.7 0.2 9.8 0.6 0.4 8.0 7.1 3.4 0.3 2.3 0.1 10.2 12.9 0.5 2.6 2.0 7.2 0.1 8.0 1.1 0.5 8.9 0.8 0.9 0.0 0.2 0.7 0.3 7.6 0.1 0.6 10.8 9.0 0.1 3.2 0.0 0.2 0.2 0.3 6.7 0.3 1.3 0.3 0.1 0.7 0.4 0.1 0.1 0.8 0.3 0.3 0.2 1.0 0.0 0.3 0.3 1.0 0.0 0.0 0.2 0.2 0.0 0.8 0.0 1.7 0.4 0.1 0.0 0.1 0.2 0.2 1.1 0.2 1.7 0.0 0.0 0.3 1.8 0.5 1.4 0.0 0.0 0.3 0.7 5.9 0.0 0.3 0.5 2.8 0.2 0.6 1.0 0.3 0.2 0.1 0.1 0.5 0.1 0.0 0.7 0.2 1.1 0.3 1.4 1.4 0.0 1.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 8.2 7.9 3.6 10.1 8.0 7.1 10.2 12.9 8.0 7.6 9.0 6.7 0.5 0.0 6.1 197.2 0.0 0.9 1.2 3.3 0.0 1.9 2.1 1.3 1.3 0.0 12.3 1.8 70.9 0.0 0.1 4.4 0.0 2.9 59.3 103.5 2.8 1.8 0.0 0.0 93.0 0.7 0.0 1.0 1.5 3.0 0.0 0.8 0.7 0.0 0.1 1.7 25.6 1.0 4.1 0.0 1.2 27.8 0.6 0.4 1.8 13.1 0.0 2.9 0.0 5.5 2.2 0.6 0.2 1.5 0.1 1.8 3.7 2.6 139.5 36.8 0.0 2.1 1.1 28.0 5.7 0.0 1.3 0.1 0.2 0.8 0.7 0.7 DNAJC2 "MPHOSPH11, MPP11, ZRF1, ZUO1, zuotin" ENSG00000105821 "DnaJ heat shock protein family (Hsp40) member C2" Q99543 7 103312289-103344830 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chaperone, Chromatin regulator" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 248.5;Spermatocytes: 238.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 61.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020454 Approved Supported Cytosol NA Yes "Cluster 42: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA020454: AB_1859492" "unprognostic (1.07e-1)" "unprognostic (1.66e-1)" "unprognostic (5.53e-2)" "unprognostic (2.20e-2)" "unprognostic (1.11e-1)" "unprognostic (7.71e-2)" "unprognostic (2.13e-3)" "unprognostic (2.13e-3)" "unprognostic (1.63e-2)" "unprognostic (5.35e-2)" "unprognostic (2.21e-2)" "unprognostic (1.27e-2)" "prognostic unfavorable (1.12e-5)" "unprognostic (1.11e-1)" "unprognostic (2.30e-1)" "unprognostic (3.51e-1)" "unprognostic (3.28e-1)" 15.7 13.4 10.2 12.2 10.7 42.0 13.4 12.7 19.2 13.1 10.5 11.9 14.7 12.8 9.7 13.8 12.1 9.8 13.5 10.5 10.4 16.4 15.7 11.2 16.8 10.0 10.7 15.7 13.4 9.0 12.6 11.9 10.3 12.3 11.9 8.7 12.6 7.7 32.5 13.6 11.9 7.4 9.3 12.2 12.9 31.3 11.4 12.3 12.7 12.7 13.2 18.8 12.8 11.8 52.7 38.1 21.4 38.7 16.1 22.6 41.6 35.1 25.8 38.5 28.6 52.9 37.2 74.9 53.7 24.4 55.2 35.5 57.5 25.7 58.4 40.6 43.4 55.1 38.7 47.3 28.6 97.9 41.2 19.6 21.9 44.9 39.4 16.2 25.6 27.8 128.3 46.2 32.0 83.8 95.0 102.1 75.9 56.8 57.0 59.7 43.0 70.1 22.8 24.8 40.6 38.7 47.7 66.2 39.7 39.6 28.1 49.8 30.8 37.5 59.9 83.3 68.1 48.9 67.8 146.0 27.3 97.9 47.6 61.3 9.0 9.3 10.9 10.3 12.1 11.7 10.9 11.7 9.4 13.7 12.5 12.5 3.6 16.4 15.3 11.2 12.8 5.9 10.2 10.7 12.7 19.2 10.5 10.4 10.0 10.7 10.3 9.3 11.4 11.8 31.3 25.6 47.0 10.7 46.1 64.6 78.7 37.3 35.3 27.1 26.3 36.6 32.3 22.8 50.2 22.0 41.7 43.7 45.9 31.1 35.2 45.0 248.5 43.8 50.1 39.6 35.3 29.9 24.7 46.0 75.5 41.0 42.8 44.2 53.7 50.1 18.5 30.6 39.6 21.9 17.9 39.0 26.4 24.5 41.3 37.3 39.4 37.8 19.6 13.1 42.9 19.3 44.3 24.1 20.6 50.2 32.9 31.2 36.9 79.2 36.4 31.0 43.4 29.0 39.5 63.7 64.8 238.7 131.9 33.5 62.1 55.4 43.2 58.3 51.9 91.5 DNAJC24 "DPH4, JJJ3, ZCSL3" ENSG00000170946 "DnaJ heat shock protein family (Hsp40) member C24" Q6P3W2 11 31369840-31432835 "Predicted intracellular proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Early spermatids: 204.8;Late spermatids: 223.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020025, HPA025237" Approved Approved Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 18: U-2197 - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA020025: AB_1847801, HPA025237: AB_1847802" "unprognostic (2.07e-1)" "unprognostic (3.73e-2)" "unprognostic (2.27e-2)" "unprognostic (9.74e-2)" "unprognostic (3.58e-2)" "unprognostic (1.76e-1)" "unprognostic (1.32e-2)" "unprognostic (3.40e-1)" "unprognostic (2.21e-2)" "unprognostic (1.49e-1)" "unprognostic (3.50e-1)" "unprognostic (1.28e-1)" "unprognostic (3.56e-1)" "unprognostic (2.74e-1)" "unprognostic (9.86e-2)" "unprognostic (1.54e-1)" "unprognostic (1.67e-1)" 7.2 6.3 6.7 5.4 6.7 1.9 6.8 8.5 8.9 4.8 5.8 4.8 4.4 5.9 6.4 5.3 3.1 4.9 11.8 7.0 7.4 6.4 6.0 4.3 6.8 6.7 7.0 4.6 7.3 4.7 4.6 5.0 6.7 5.7 4.4 8.3 5.8 5.9 17.0 8.8 4.5 6.3 6.5 5.8 5.0 4.4 6.9 5.2 6.6 11.3 5.7 5.6 3.4 7.1 4.8 6.4 11.2 8.2 8.7 10.9 4.9 12.7 8.0 7.0 7.3 5.2 4.5 6.3 6.7 8.6 10.4 6.2 6.4 8.2 12.2 14.8 11.9 6.9 10.2 5.3 11.1 14.0 10.9 10.3 10.4 4.3 13.8 10.2 9.5 10.7 13.3 10.9 14.0 5.0 10.8 9.4 5.7 7.0 6.7 6.7 18.8 6.5 10.3 4.5 4.9 6.9 11.0 7.5 11.0 6.3 10.5 9.1 10.0 13.1 8.9 16.3 15.8 13.3 11.3 7.6 19.3 6.6 14.9 4.5 1.0 0.9 2.2 1.8 3.1 1.5 2.2 1.9 0.8 1.6 2.8 2.9 0.7 1.3 1.1 1.6 1.5 1.3 6.7 6.7 8.5 8.9 7.0 7.4 6.7 7.0 6.7 6.5 6.9 7.1 7.5 3.2 7.4 14.0 14.4 12.1 7.0 9.2 6.8 11.9 9.1 7.2 20.3 1.5 9.3 3.7 10.4 8.6 15.5 5.6 3.9 9.1 204.8 6.4 11.0 7.7 7.2 5.2 40.7 9.1 9.4 10.4 7.1 6.3 5.1 5.3 9.3 10.5 8.2 23.5 28.9 5.1 4.1 6.9 10.3 223.9 9.0 8.5 12.4 25.3 7.1 26.2 9.2 41.2 29.9 11.7 6.2 9.4 18.5 7.2 5.2 11.4 4.4 14.6 0.0 9.6 8.3 28.2 18.2 9.5 8.2 6.3 13.5 7.1 5.9 9.1 DNAJC27 "RabJS, RBJ" ENSG00000115137 "DnaJ heat shock protein family (Hsp40) member C27" Q9NZQ0 2 24943636-24972094 "Predicted intracellular proteins" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 22.2" "Cell type enhanced" "Detected in many" "Early spermatids: 59.8;Spermatocytes: 70.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036815, HPA036816" Uncertain Approved Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 29: U-266 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA036815: , HPA036816: AB_10673506" "unprognostic (1.67e-1)" "unprognostic (1.36e-1)" "unprognostic (1.63e-1)" "unprognostic (4.53e-2)" "unprognostic (3.09e-1)" "unprognostic (5.17e-3)" "unprognostic (5.41e-2)" "unprognostic (5.58e-3)" "unprognostic (2.13e-1)" "unprognostic (4.60e-2)" "unprognostic (7.44e-4)" "unprognostic (8.84e-2)" "prognostic favorable (8.48e-5)" "unprognostic (3.35e-1)" "unprognostic (3.66e-1)" "unprognostic (3.05e-2)" "unprognostic (1.78e-3)" 5.6 3.4 4.3 2.1 5.6 3.8 3.7 7.1 7.0 3.7 4.1 3.7 1.9 4.2 5.0 2.2 4.6 3.0 4.9 4.6 8.7 3.8 2.0 2.7 2.7 7.5 6.5 7.0 2.7 5.1 6.1 2.9 8.2 3.3 2.7 13.3 2.2 3.1 4.6 2.9 2.7 3.0 5.7 2.9 2.9 22.2 6.0 3.5 3.3 7.0 2.4 3.1 2.9 6.5 2.8 1.2 2.6 2.6 3.6 3.0 2.0 2.1 3.2 2.2 1.9 1.3 1.3 2.6 0.5 1.5 1.8 2.2 1.9 1.3 2.3 1.1 1.6 1.6 1.6 1.2 2.3 1.5 2.2 2.3 2.2 1.7 3.5 2.5 0.9 3.1 1.1 2.4 2.4 1.0 2.7 2.6 1.7 1.0 1.1 1.6 5.1 1.4 2.1 1.5 0.9 3.2 2.0 1.5 3.0 2.7 1.3 1.1 0.8 2.9 2.0 1.5 2.0 6.1 2.3 3.1 1.5 2.4 1.3 0.0 0.2 0.9 0.2 0.1 0.5 0.4 0.3 0.2 0.2 0.3 0.4 0.5 0.0 1.3 0.3 0.1 0.3 0.2 4.3 5.6 7.1 7.0 4.6 8.7 7.5 6.5 8.2 5.7 6.0 6.5 7.8 9.6 10.0 19.2 11.2 2.0 5.6 3.6 8.0 24.1 9.8 8.5 25.4 4.3 3.0 7.3 37.5 3.6 10.8 4.5 3.9 2.6 59.8 12.5 9.7 7.7 15.5 11.8 18.2 2.5 2.0 8.8 8.2 5.2 10.8 9.5 6.1 3.4 3.3 37.0 22.1 5.9 6.1 3.2 4.6 32.5 8.7 5.9 1.8 7.5 4.3 12.2 4.1 12.1 24.1 1.7 0.9 6.4 8.8 4.6 4.3 3.1 17.3 25.1 0.0 12.8 23.9 70.7 17.0 8.3 3.3 4.2 11.3 23.2 5.4 3.8 DNPEP "ASPEP, DAP" ENSG00000123992 "Aspartyl aminopeptidase" Q9ULA0 2 219372043-219400022 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 364.4;Late spermatids: 462.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036398, HPA044860" Enhanced Supported Cytosol NA NA 2700000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA036398: AB_10970915, HPA044860: AB_10961275" "unprognostic (3.71e-1)" "unprognostic (6.45e-2)" "unprognostic (1.26e-1)" "unprognostic (1.05e-2)" "unprognostic (1.55e-2)" "unprognostic (2.75e-1)" "unprognostic (2.54e-3)" "unprognostic (3.34e-2)" "unprognostic (2.44e-1)" "unprognostic (3.49e-2)" "unprognostic (1.61e-1)" "unprognostic (6.13e-2)" "unprognostic (1.67e-1)" "unprognostic (5.63e-3)" "unprognostic (3.49e-1)" "unprognostic (2.50e-1)" "unprognostic (1.85e-3)" 25.8 18.9 15.4 25.0 15.8 18.0 23.6 14.8 18.6 24.9 14.7 34.5 56.5 22.4 21.5 25.1 25.1 22.6 39.9 16.2 16.9 22.1 32.0 27.6 23.4 15.8 15.0 30.2 27.2 25.8 13.0 37.1 15.2 22.6 30.8 9.5 26.2 24.4 64.5 31.7 56.2 19.9 16.0 24.7 25.4 58.5 17.4 17.5 15.2 46.4 16.2 29.6 21.6 14.7 47.5 25.8 15.4 45.7 39.7 32.2 122.0 23.0 46.5 59.3 62.5 72.6 61.2 27.2 48.7 49.5 76.0 45.0 18.6 53.6 21.3 56.4 12.5 46.6 25.0 79.8 107.2 38.9 32.2 54.4 55.4 61.8 50.2 37.9 41.2 38.6 53.8 45.3 31.0 103.7 60.8 44.5 25.5 67.7 15.1 77.2 35.7 36.5 33.0 74.0 19.1 26.0 27.1 86.5 34.5 26.9 25.8 43.3 23.5 55.4 46.1 31.4 33.7 49.6 31.8 21.3 80.0 37.7 24.1 8.7 17.2 7.3 16.1 19.7 18.8 13.2 13.2 18.3 20.8 16.2 14.0 18.7 1.6 21.2 17.0 7.2 16.6 14.8 15.4 15.8 14.8 18.6 16.2 16.9 15.8 15.0 15.2 16.0 17.4 14.7 43.1 12.8 18.2 8.8 35.6 38.6 74.1 55.1 52.9 19.3 41.2 36.7 33.6 55.8 27.2 25.8 33.3 90.4 26.7 70.4 49.0 62.9 364.4 16.5 36.5 41.8 48.0 19.8 3.1 66.3 96.9 43.4 29.0 19.6 24.1 39.1 30.4 47.9 51.0 10.1 5.2 110.3 38.7 31.5 26.8 462.0 52.5 26.2 32.0 4.7 53.0 29.8 45.3 3.0 3.3 52.3 75.6 41.0 38.3 113.1 202.6 79.6 16.3 37.6 26.3 31.9 120.0 20.1 20.1 43.4 44.8 66.4 34.1 36.9 70.9 74.6 DOCK3 "KIAA0299, MOCA, PBP" ENSG00000088538 "Dedicator of cytokinesis 3" Q8IZD9 3 50674927-51384198 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.5;thyroid gland: 12.2" "Group enriched" "Detected in some" 11 "Astrocytes: 223.6;Excitatory neurons: 777.2;Inhibitory neurons: 837.1;Oligodendrocyte precursor cells: 445.4;Oligodendrocytes: 814.7" "Group enriched" "Detected in many" 4 "glioma: 2.7;thyroid cancer: 7.6" "Group enriched" "Detected in many" 8 "amygdala: 9.9;basal ganglia: 12.8;cerebral cortex: 17.5;hippocampal formation: 13.4;white matter: 17.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 6.1;GAMG: 5.9;HMC-1: 4.9;JURKAT: 5.8;U-87 MG: 7.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037543, HPA037544" Enhanced Supported Enhanced Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA037543: AB_10672495, HPA037544: AB_10670383" "unprognostic (1.02e-1)" "unprognostic (1.11e-1)" "unprognostic (1.78e-3)" "unprognostic (6.35e-8)" "unprognostic (2.63e-1)" "unprognostic (3.02e-2)" "unprognostic (4.64e-2)" "unprognostic (3.67e-1)" "unprognostic (1.91e-1)" "unprognostic (7.99e-2)" "unprognostic (2.36e-3)" "unprognostic (1.34e-2)" "unprognostic (1.45e-2)" "unprognostic (5.83e-5)" "unprognostic (7.96e-2)" "unprognostic (6.19e-2)" "unprognostic (1.24e-1)" 0.8 3.3 9.9 0.2 12.8 0.2 0.3 0.9 17.5 0.9 0.0 3.1 0.2 0.7 0.7 2.1 0.8 0.3 2.9 13.4 0.8 0.8 0.1 0.5 0.3 1.3 0.4 0.4 0.4 5.3 6.4 0.1 1.2 2.0 0.3 10.1 1.5 1.9 1.9 2.4 0.8 1.0 0.0 0.5 1.4 5.9 1.7 0.0 12.2 1.8 0.3 2.0 0.6 17.2 0.1 0.2 0.2 6.1 0.0 0.0 2.6 0.1 0.1 0.3 0.2 0.1 0.4 0.0 0.5 1.9 5.9 0.4 4.1 0.0 0.1 3.7 4.3 0.1 1.2 0.1 0.0 0.1 4.9 0.0 0.1 0.2 0.0 0.3 0.0 5.8 0.0 0.1 0.5 0.2 0.0 0.0 2.0 0.3 1.9 0.0 0.6 0.0 0.3 0.6 3.7 0.0 0.3 3.4 0.0 4.1 0.1 0.0 0.4 0.2 1.6 0.2 2.2 0.3 0.0 0.0 7.9 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.0 9.9 12.8 0.9 17.5 13.4 0.8 1.3 0.4 1.2 0.0 1.7 17.2 0.0 0.0 0.6 223.6 0.0 0.0 0.2 0.0 0.0 22.0 0.3 0.4 7.5 0.0 0.7 0.0 2.1 0.1 0.4 0.1 1.9 0.0 11.4 0.3 0.2 0.4 0.0 0.0 777.2 0.0 0.2 0.8 0.0 0.2 0.0 0.1 0.0 0.0 0.5 33.7 837.1 0.0 0.0 0.0 0.0 6.0 0.0 0.4 0.0 52.5 0.0 3.1 1.0 445.4 814.7 0.3 0.0 0.0 0.5 0.1 0.0 0.2 0.1 5.1 0.0 1.1 1.2 6.0 4.1 0.4 0.1 0.0 1.1 0.1 0.0 0.1 DOCK5 FLJ21034 ENSG00000147459 "Dedicator of cytokinesis 5" Q9H7D0 8 25184689-25418082 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 86.0" "Cell type enriched" "Detected in many" 7 "Oligodendrocytes: 789.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 30.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 30.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017719, HPA056837" Approved Enhanced Cytosol No No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 70: Brain - Nervous system development" "Cluster 20: HeLa - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA017719: AB_1847820, HPA056837: AB_2683253" "unprognostic (2.16e-1)" "unprognostic (3.55e-3)" "unprognostic (1.25e-2)" "prognostic favorable (1.91e-4)" "unprognostic (8.44e-2)" "unprognostic (1.24e-1)" "unprognostic (2.61e-2)" "unprognostic (2.88e-2)" "unprognostic (1.69e-2)" "unprognostic (4.21e-2)" "unprognostic (4.18e-3)" "unprognostic (3.00e-1)" "prognostic unfavorable (1.18e-6)" "unprognostic (2.81e-1)" "unprognostic (3.07e-1)" "unprognostic (1.30e-2)" "unprognostic (2.25e-1)" 4.9 3.4 17.1 7.5 56.6 17.0 4.8 33.4 30.0 4.4 25.2 8.4 10.6 4.1 5.1 3.4 6.2 5.8 7.8 19.5 29.1 4.3 15.2 9.3 1.8 43.4 39.9 6.8 4.7 2.6 8.2 10.2 43.6 7.9 9.4 2.5 6.7 5.6 2.6 5.4 12.9 3.3 19.3 19.3 6.6 6.2 40.7 1.9 15.5 2.8 1.6 4.1 4.9 86.0 19.8 43.2 4.1 0.3 9.8 10.6 14.2 45.5 26.5 12.4 9.6 6.3 15.5 0.4 4.0 40.3 13.7 34.6 4.9 32.5 19.9 6.2 6.1 20.2 40.5 15.8 11.1 5.0 21.6 7.3 12.9 13.6 20.3 13.6 10.7 0.8 0.3 0.8 12.2 11.5 0.7 9.5 4.1 24.4 11.9 0.3 9.0 0.5 9.1 12.0 3.0 1.4 24.0 14.5 4.7 3.4 4.5 4.0 32.1 21.1 13.6 25.5 17.1 0.7 0.2 0.3 27.4 10.2 27.4 14.6 2.5 3.8 0.4 5.5 0.1 0.0 0.1 0.0 2.3 0.0 0.0 0.3 30.7 0.4 6.8 0.4 0.0 0.3 17.1 56.6 33.4 30.0 19.5 29.1 43.4 39.9 43.6 19.3 40.7 86.0 2.7 44.8 41.5 96.6 2.2 18.5 13.2 30.5 2.2 9.6 12.8 5.8 13.4 31.5 31.4 14.7 2.1 28.3 20.1 50.6 0.0 10.3 0.9 16.3 10.0 10.6 17.5 9.9 4.9 12.0 100.2 28.1 32.1 53.1 31.0 52.8 8.2 35.0 13.3 1.7 3.6 26.7 8.2 60.3 51.0 5.6 28.9 41.3 85.4 38.4 24.5 20.0 22.6 61.3 789.8 48.9 27.4 48.2 13.4 36.0 60.0 6.2 20.9 2.3 13.1 4.0 12.1 0.9 5.6 5.8 7.2 20.5 10.8 25.1 27.7 16.8 DOCK6 "KIAA1395, ZIR1" ENSG00000130158 "Dedicator of cytokinesis 6" Q96HP0 19 11199295-11262524 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 70.3;Cardiomyocytes: 185.4;Endothelial cells: 64.8;Hepatic stellate cells: 55.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 68.2;TIME: 68.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049423, HPA049424" Approved Supported Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 43: Cardiomyocytes - Nuclear processes" Cytosol "HPA049423: AB_2680760, HPA049424: AB_2680761" "unprognostic (2.69e-2)" "unprognostic (2.27e-1)" "unprognostic (9.51e-2)" "unprognostic (3.35e-2)" "unprognostic (4.72e-3)" "prognostic favorable (9.09e-4)" "unprognostic (2.54e-2)" "unprognostic (4.91e-1)" "unprognostic (1.23e-1)" "unprognostic (1.65e-2)" "unprognostic (2.57e-1)" "unprognostic (7.89e-2)" "unprognostic (1.25e-3)" "unprognostic (2.76e-1)" "unprognostic (1.51e-1)" "unprognostic (5.41e-2)" "unprognostic (2.95e-1)" 31.2 9.9 7.4 5.4 6.3 0.4 27.5 4.5 9.7 15.4 3.6 16.8 14.2 14.7 4.6 16.8 11.6 12.0 29.6 4.6 5.1 26.3 13.2 46.3 4.9 7.8 7.1 12.0 14.4 5.4 11.9 15.0 6.9 14.8 6.2 1.8 11.4 7.5 15.1 25.2 15.4 7.1 5.7 14.5 15.8 5.8 11.4 2.1 29.0 9.3 2.6 14.2 16.6 5.6 14.6 8.9 9.9 8.1 7.3 10.5 15.9 4.2 6.9 4.1 6.3 16.9 11.2 0.9 25.4 7.1 3.9 8.3 4.3 22.3 2.5 12.4 7.0 2.8 2.2 12.8 11.8 4.3 13.7 8.1 13.0 7.5 17.0 7.9 68.2 0.3 15.7 0.0 9.1 32.7 0.1 14.7 12.5 13.2 16.6 0.9 6.7 14.0 6.8 20.0 0.6 17.6 4.2 4.2 7.6 6.5 4.9 7.6 68.8 7.5 7.8 17.1 7.6 1.2 0.2 14.1 6.3 3.2 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 6.3 4.5 9.7 4.6 5.1 7.8 7.1 6.9 5.7 11.4 5.6 70.3 3.2 12.6 6.8 0.9 6.5 6.2 8.5 4.6 1.4 4.3 3.8 185.4 5.7 11.3 25.8 0.0 0.3 0.9 15.6 1.9 5.4 3.5 3.9 8.9 64.8 12.1 0.0 2.9 6.8 1.3 19.6 35.2 7.2 5.1 4.7 55.3 5.6 4.6 0.0 5.9 15.9 8.2 2.5 4.4 1.3 22.4 1.6 3.6 35.6 0.0 4.6 0.0 7.1 3.5 11.9 10.9 9.4 1.9 8.4 11.9 1.9 9.2 2.6 19.7 8.4 30.8 1.5 4.3 7.4 11.5 0.5 1.2 7.8 9.7 9.0 DOK1 p62dok ENSG00000115325 "Docking protein 1" Q99704 2 74549026-74557551 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "granulocytes: 36.8;Hofbauer cells: 48.6;Macrophages: 31.2;monocytes: 41.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 76.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004224, HPA048561" Approved Supported Cytosol NA NA 80000 "Cluster 14: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB004224: AB_627447, HPA048561: AB_2680443" "unprognostic (2.40e-2)" "unprognostic (2.07e-2)" "unprognostic (2.60e-1)" "prognostic favorable (8.42e-4)" "unprognostic (9.86e-3)" "unprognostic (1.28e-1)" "unprognostic (7.10e-2)" "prognostic favorable (4.64e-4)" "unprognostic (7.57e-2)" "unprognostic (1.85e-2)" "unprognostic (1.89e-2)" "unprognostic (3.15e-2)" "prognostic unfavorable (3.16e-6)" "unprognostic (8.65e-2)" "unprognostic (2.40e-2)" "unprognostic (1.37e-1)" "unprognostic (1.20e-2)" 10.8 3.7 8.8 10.2 8.3 13.7 4.7 8.2 9.0 6.6 7.6 5.2 4.4 4.9 0.7 1.4 6.3 3.2 2.8 7.8 8.7 2.7 1.5 6.6 12.3 10.7 8.7 4.2 3.7 6.3 2.2 4.0 9.2 3.1 3.8 0.9 3.0 4.0 1.1 1.6 5.8 4.8 9.2 11.6 6.7 1.7 9.4 7.6 3.9 1.7 10.1 4.7 2.7 9.0 5.3 2.0 6.0 3.0 13.9 16.8 4.2 12.8 10.0 5.2 8.5 1.6 6.1 3.3 18.0 12.3 11.3 0.7 6.1 2.8 1.9 76.3 5.7 43.1 4.4 0.3 10.0 22.0 41.0 12.5 0.0 28.5 14.7 21.7 6.2 13.8 12.7 9.5 10.5 5.6 15.8 45.7 11.1 10.8 1.6 13.0 12.9 3.5 2.7 4.5 2.0 10.0 2.5 0.7 6.7 1.7 3.3 24.1 11.7 32.7 15.1 15.3 2.9 12.6 9.6 0.1 32.9 35.3 5.5 39.0 52.3 38.9 17.3 51.4 13.9 22.9 14.1 15.4 51.3 26.3 10.3 10.3 52.9 27.4 59.3 10.8 24.3 39.8 8.8 8.3 8.2 9.0 7.8 8.7 10.7 8.7 9.2 9.2 9.4 9.0 6.7 9.6 8.8 2.9 15.0 2.0 1.1 3.7 1.2 0.5 2.2 2.8 1.8 4.3 2.0 5.5 0.0 1.9 13.6 8.7 0.0 11.9 0.3 7.4 5.8 7.2 3.0 12.4 0.1 9.1 4.2 6.5 6.1 5.6 36.8 5.8 9.7 0.6 48.6 1.7 0.5 5.9 2.0 26.3 24.2 1.0 5.0 31.2 3.6 4.7 41.1 9.8 16.5 0.5 0.6 10.2 10.0 6.0 6.3 2.4 8.1 3.9 1.7 0.5 6.6 4.1 8.3 0.5 2.1 0.3 1.6 2.3 13.5 7.0 6.8 1.6 DOK4 FLJ10488 ENSG00000125170 "Docking protein 4" Q8TEW6 16 57471922-57487327 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 127.9;Paneth cells: 99.9;Proximal enterocytes: 96.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A549: 94.2;CACO-2: 107.8;SH-SY5Y: 239.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008348, HPA055849" Supported Approved Cytosol NA No "Cluster 1: Neutrophils - Mixed function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA008348: , HPA055849: AB_2682942" "unprognostic (3.44e-2)" "unprognostic (2.04e-2)" "unprognostic (1.17e-1)" "unprognostic (4.73e-2)" "unprognostic (3.66e-1)" "unprognostic (9.71e-2)" "unprognostic (5.35e-2)" "unprognostic (1.39e-1)" "unprognostic (1.13e-2)" "unprognostic (3.00e-2)" "unprognostic (2.27e-2)" "unprognostic (1.53e-1)" "unprognostic (2.58e-3)" "unprognostic (4.30e-2)" "unprognostic (2.21e-1)" "unprognostic (4.42e-3)" "unprognostic (1.18e-3)" 10.5 9.2 12.0 9.6 12.2 1.8 8.8 12.2 12.7 20.7 9.0 43.9 46.1 16.9 12.1 32.8 15.2 17.5 14.8 11.1 11.8 42.0 33.7 23.3 4.3 8.3 11.0 19.8 17.6 12.0 19.8 10.9 13.0 18.3 31.3 4.1 12.6 25.8 3.0 43.2 49.9 12.2 7.5 10.5 37.3 7.0 10.8 3.8 10.7 3.9 7.4 16.7 21.6 9.4 10.3 94.2 15.0 26.8 20.6 22.6 16.7 17.7 23.5 12.4 3.8 107.8 53.1 1.1 75.4 37.2 7.3 21.0 9.2 4.9 5.3 2.7 6.9 22.3 28.2 63.2 29.3 0.3 2.3 15.8 14.2 16.4 1.8 27.6 19.0 3.8 7.3 4.3 14.9 9.9 1.1 4.1 9.6 46.1 4.0 8.9 7.8 1.2 64.8 3.9 73.6 239.9 14.5 6.3 4.5 66.0 5.6 4.2 20.5 2.1 15.1 6.1 0.8 2.9 4.1 0.8 6.7 4.7 9.3 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 12.0 12.2 12.2 12.7 11.1 11.8 8.3 11.0 13.0 7.5 10.8 9.4 8.3 12.8 14.0 0.7 1.4 7.9 7.2 3.6 5.2 15.5 3.7 5.0 2.4 30.0 3.3 14.7 0.0 0.9 1.8 127.9 5.9 15.0 1.2 2.1 5.3 11.3 3.6 1.3 5.0 23.7 7.6 7.9 36.2 2.9 0.0 19.6 6.8 20.4 0.9 8.4 7.1 30.3 2.0 0.8 1.6 2.0 13.4 1.0 3.6 1.0 0.7 2.2 0.0 2.0 0.4 30.8 99.9 12.0 1.4 7.1 96.6 46.9 2.5 0.8 6.6 1.1 6.9 0.2 4.1 11.6 18.0 0.5 2.5 4.8 34.1 6.1 DPP3 ENSG00000254986 "Dipeptidyl peptidase 3" Q9NY33 11 66480013-66509657 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035780, HPA035781" Approved Supported Cytosol NA NA 3200000 "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol "HPA035780: AB_2674778, HPA035781: AB_10669529" "unprognostic (5.74e-2)" "unprognostic (1.16e-3)" "unprognostic (2.62e-3)" "unprognostic (4.77e-2)" "unprognostic (1.99e-1)" "unprognostic (5.44e-3)" "unprognostic (1.67e-3)" "unprognostic (1.25e-3)" "unprognostic (1.73e-2)" "unprognostic (9.87e-2)" "unprognostic (1.02e-2)" "unprognostic (3.87e-1)" "unprognostic (5.85e-2)" "prognostic favorable (1.34e-4)" "unprognostic (1.81e-2)" "unprognostic (3.43e-1)" "unprognostic (5.66e-2)" 11.6 17.5 8.2 21.4 9.1 20.7 11.2 10.2 10.4 11.0 5.4 30.2 24.8 11.7 7.8 23.5 9.8 14.5 10.3 8.4 8.9 17.1 18.6 14.3 21.8 10.2 8.8 6.8 17.3 11.9 8.7 14.3 10.8 14.4 26.3 15.9 18.8 12.9 26.5 13.6 20.5 16.2 8.6 15.4 19.2 9.8 10.2 18.6 11.7 7.4 23.3 17.3 13.5 9.9 84.1 71.6 32.5 36.3 26.4 28.3 50.4 46.5 61.8 61.4 40.7 90.8 68.4 48.7 154.0 52.9 52.2 73.6 52.1 57.0 39.4 92.5 23.8 63.1 32.1 54.2 40.7 77.6 101.1 40.5 54.5 46.2 22.8 26.5 47.8 50.1 45.1 28.2 56.7 95.3 91.0 78.7 55.5 82.0 43.2 63.1 32.7 79.6 52.6 71.7 61.1 52.2 39.7 45.6 62.5 30.3 70.8 44.7 50.1 36.5 39.4 40.7 46.2 23.3 46.6 56.6 48.5 36.5 45.9 20.7 18.8 21.3 21.4 40.0 13.3 11.5 15.8 17.7 32.3 11.1 9.4 13.9 3.2 30.8 27.9 22.5 29.6 17.7 8.2 9.1 10.2 10.4 8.4 8.9 10.2 8.8 10.8 8.6 10.2 9.9 5.8 16.0 13.2 6.8 11.6 6.0 17.4 34.8 8.6 11.4 7.1 3.8 3.0 10.0 27.0 23.9 10.4 46.9 11.5 41.6 13.7 45.6 24.6 8.7 6.2 10.5 18.6 3.4 3.4 61.3 34.2 7.4 29.0 11.5 1.3 9.9 3.6 14.7 37.4 6.7 4.0 19.5 63.1 7.9 9.0 7.0 2.1 10.8 16.0 3.7 31.3 21.6 18.6 4.5 5.6 40.8 25.2 5.3 15.7 11.0 26.4 28.7 17.3 72.9 13.1 4.4 16.2 8.8 20.7 14.4 6.0 36.0 13.1 20.1 29.5 19.5 DPP8 "DP8, DPRP1, FLJ14920, FLJ20283, MGC26191, MSTP141" ENSG00000074603 "Dipeptidyl peptidase 8" Q6V1X1 15 65442463-65517704 "Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Aminopeptidase, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008706 Approved Supported Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA008706: AB_1078665" "unprognostic (3.65e-1)" "unprognostic (2.38e-2)" "unprognostic (2.15e-1)" "unprognostic (1.13e-1)" "unprognostic (1.24e-1)" "unprognostic (8.60e-2)" "unprognostic (2.98e-1)" "unprognostic (2.46e-1)" "unprognostic (2.52e-2)" "unprognostic (1.81e-1)" "unprognostic (4.09e-2)" "unprognostic (3.60e-2)" "unprognostic (1.99e-2)" "unprognostic (1.01e-1)" "unprognostic (7.58e-2)" "unprognostic (8.56e-2)" "unprognostic (2.59e-1)" 12.7 10.2 7.0 12.1 8.5 14.9 11.8 9.3 11.3 11.8 5.5 11.4 14.4 11.7 9.7 10.0 8.3 9.7 14.9 8.3 9.2 12.7 7.9 11.1 12.9 7.3 8.3 10.8 7.4 15.2 5.7 11.2 7.2 10.8 12.9 15.4 9.5 11.5 27.5 9.8 13.5 13.1 8.5 14.8 11.0 26.1 9.7 13.8 14.1 30.6 11.3 11.2 8.3 9.7 14.1 24.4 15.7 15.8 17.4 25.2 12.8 22.5 28.4 21.1 20.3 10.6 12.6 25.1 16.3 30.3 14.5 25.9 30.6 17.6 26.0 20.9 17.2 24.2 18.1 10.4 17.9 34.3 23.8 18.6 18.3 17.0 16.0 18.5 23.2 19.2 16.4 24.1 26.5 12.5 17.1 12.0 9.9 15.7 11.1 22.6 27.9 24.7 19.8 32.7 10.5 17.0 14.3 15.8 25.3 15.6 14.4 22.5 28.6 28.2 19.2 12.7 25.5 26.9 42.2 25.8 21.3 32.8 20.4 30.5 11.7 15.1 12.1 11.7 12.6 11.8 10.0 11.2 10.9 12.2 9.5 10.6 20.9 8.2 15.8 8.6 11.3 7.2 7.0 8.5 9.3 11.3 8.3 9.2 7.3 8.3 7.2 8.5 9.7 9.7 39.1 35.3 27.9 65.6 30.0 13.4 15.0 20.4 15.9 24.1 21.1 14.2 43.4 21.5 25.4 14.7 37.5 20.4 35.3 25.8 23.5 22.7 57.4 17.3 19.3 39.5 25.9 17.9 50.1 30.0 15.2 22.3 31.1 17.5 27.8 24.7 46.1 18.2 21.5 28.6 58.6 27.0 16.2 36.0 15.1 59.7 29.2 31.9 23.2 38.4 47.6 32.3 45.3 36.2 57.1 38.4 25.8 29.3 24.7 19.3 24.2 27.5 25.9 28.1 19.7 29.9 22.1 69.3 24.4 21.9 20.2 17.6 28.5 46.5 26.7 23.6 DPP9 ENSG00000142002 "Dipeptidyl peptidase 9" Q86TI2 19 4675224-4724673 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 203.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036059 Approved Supported Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" Cytosol "HPA036059: AB_10671240" "prognostic favorable (4.96e-4)" "unprognostic (4.16e-2)" "unprognostic (2.03e-1)" "prognostic favorable (6.21e-5)" "unprognostic (5.67e-2)" "unprognostic (8.30e-2)" "unprognostic (1.66e-1)" "unprognostic (1.23e-1)" "unprognostic (8.85e-2)" "unprognostic (6.38e-2)" "unprognostic (1.93e-1)" "unprognostic (3.39e-2)" "prognostic unfavorable (3.38e-8)" "prognostic favorable (7.72e-5)" "unprognostic (1.55e-1)" "unprognostic (4.22e-1)" "unprognostic (1.80e-1)" 19.6 16.2 12.2 24.5 13.8 32.8 19.4 12.9 13.7 20.1 25.0 24.2 20.1 20.3 5.9 24.5 16.3 13.5 32.2 13.2 11.7 16.9 57.2 27.4 24.9 14.8 14.3 17.3 20.6 10.1 12.7 12.9 14.3 18.9 13.8 9.5 17.7 12.8 71.0 23.8 26.3 15.3 12.3 28.4 21.1 9.0 16.1 17.9 16.9 23.0 17.1 23.2 20.2 15.4 77.5 60.4 17.6 27.5 26.2 36.3 31.7 44.3 58.5 73.1 47.4 54.3 58.2 36.5 32.8 57.7 49.1 51.7 35.9 203.9 44.5 47.3 34.8 26.8 33.6 47.2 40.0 47.2 55.8 27.9 46.6 114.4 67.2 62.2 66.8 25.0 37.4 78.3 64.1 21.2 54.2 30.0 36.0 30.4 89.0 34.0 37.4 42.4 38.3 52.5 24.8 22.2 38.2 67.8 29.5 18.1 18.8 38.2 54.5 64.9 28.0 101.6 89.6 54.6 62.3 36.8 63.4 53.7 55.7 10.8 7.1 7.7 10.6 8.3 7.9 8.0 4.7 8.5 7.1 4.8 4.5 7.3 3.7 11.4 6.5 3.3 9.7 7.7 12.2 13.8 12.9 13.7 13.2 11.7 14.8 14.3 14.3 12.3 16.1 15.4 21.8 28.9 25.8 14.4 18.8 7.9 13.6 10.2 10.8 18.6 12.2 12.3 14.6 10.0 11.2 3.7 37.5 11.7 22.7 37.4 3.9 12.4 2.0 12.7 14.6 19.4 12.5 7.6 10.1 12.8 18.3 10.7 36.2 22.8 17.1 13.3 17.2 39.5 19.0 23.5 10.2 21.3 6.1 20.4 17.6 3.9 9.9 22.0 5.4 16.9 42.2 9.0 25.7 7.5 13.7 26.6 28.4 9.4 32.9 15.6 20.1 5.1 9.5 30.8 19.7 21.7 12.4 7.5 6.9 12.4 5.5 15.6 21.2 12.8 20.6 16.7 DPYSL3 "CRMP4, DRP-3, ULIP" ENSG00000113657 "Dihydropyrimidinase like 3" Q14195 5 147390808-147510068 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 101.5;Cone photoreceptor cells: 331.5;Granulosa cells: 261.9;Peritubular cells: 205.7;Rod photoreceptor cells: 125.0" "Cancer enhanced" "Detected in all" "glioma: 109.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SH-SY5Y: 685.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010948 Approved Approved Cytosol NA NA 740000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA010948: AB_1847245" "unprognostic (3.92e-2)" "unprognostic (1.90e-1)" "unprognostic (5.00e-3)" "unprognostic (1.39e-1)" "unprognostic (1.03e-1)" "unprognostic (1.59e-1)" "unprognostic (2.30e-2)" "unprognostic (5.99e-2)" "unprognostic (6.92e-2)" "unprognostic (4.72e-2)" "unprognostic (2.08e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (3.87e-9)" "unprognostic (1.14e-2)" "unprognostic (1.73e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (8.23e-4)" 58.4 18.6 63.4 54.4 68.6 0.8 37.5 60.3 55.8 66.1 30.4 142.1 18.4 119.9 73.9 69.0 63.4 65.1 59.2 57.0 116.0 7.7 4.4 45.2 18.1 123.7 94.2 88.0 5.5 2.7 12.7 19.8 81.8 104.6 37.6 163.8 24.5 162.0 68.7 23.8 43.3 217.6 115.2 26.4 40.9 19.9 95.2 7.1 22.4 36.0 27.0 118.0 50.6 105.1 0.5 36.1 63.9 0.1 2.3 63.3 1.6 34.1 163.0 71.4 94.4 114.5 3.1 0.0 9.6 100.1 37.4 3.7 13.1 1.4 79.1 16.3 29.2 0.1 30.0 0.2 63.1 0.3 0.2 12.2 0.6 153.8 60.3 178.7 206.9 0.0 0.0 1.3 41.1 0.3 0.2 0.6 135.9 0.2 53.7 0.2 135.1 0.5 63.0 14.2 47.1 685.4 0.3 0.3 10.8 87.9 0.5 1.0 91.1 51.6 38.5 127.0 127.3 113.9 21.7 0.2 47.5 1.4 27.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 63.4 68.6 60.3 55.8 57.0 116.0 123.7 94.2 81.8 115.2 95.2 105.1 59.9 0.0 2.8 101.5 0.0 9.4 3.4 1.5 2.2 14.2 8.1 6.6 7.8 1.5 4.0 0.0 331.5 0.1 0.0 0.2 0.0 9.1 16.8 0.3 4.6 62.6 6.6 0.0 11.3 8.4 0.3 79.8 3.1 1.2 1.3 261.9 57.8 0.4 1.6 5.0 12.9 0.2 24.4 1.2 11.9 19.2 42.9 3.1 19.6 5.6 0.0 28.3 0.0 83.9 0.7 13.7 0.0 205.7 0.3 10.1 0.0 0.1 2.8 125.0 0.0 23.6 40.9 1.8 3.2 3.7 8.2 0.4 1.5 49.6 0.3 4.5 DRAP1 NC2-alpha ENSG00000175550 "DR1 associated protein 1" Q14919 11 65919274-65921563 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 813.2;Suprabasal keratinocytes: 1015.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 1032.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006790 Uncertain Approved Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 28: Keratinocytes - Keratinization" Cytosol "HPA006790: AB_1078702" "unprognostic (1.69e-2)" "unprognostic (1.02e-2)" "unprognostic (1.01e-1)" "unprognostic (3.01e-2)" "unprognostic (1.84e-2)" "unprognostic (4.06e-2)" "unprognostic (4.89e-3)" "unprognostic (5.58e-2)" "unprognostic (8.47e-2)" "unprognostic (4.23e-2)" "unprognostic (1.98e-1)" "unprognostic (3.82e-2)" "prognostic unfavorable (3.73e-5)" "unprognostic (4.70e-2)" "unprognostic (1.38e-1)" "prognostic favorable (4.96e-5)" "unprognostic (1.62e-1)" 87.4 86.4 119.0 71.0 120.8 96.8 80.3 121.2 162.8 91.0 103.7 104.4 56.1 89.3 27.9 107.5 74.0 34.9 129.2 120.3 132.4 75.0 76.2 75.1 71.0 119.9 119.6 67.4 73.3 62.6 81.2 43.1 121.5 73.1 21.1 25.1 58.3 48.0 197.1 112.5 62.9 40.2 118.1 85.6 69.9 173.1 120.7 96.6 118.9 78.5 39.2 84.2 83.4 131.6 578.7 226.8 108.3 200.0 99.9 195.3 75.9 634.9 273.2 344.1 223.6 85.6 302.7 142.2 277.3 420.3 395.5 222.7 42.7 292.0 138.2 187.7 70.1 173.4 103.8 85.4 186.0 145.8 228.2 123.7 126.6 365.8 246.7 191.4 142.2 138.9 78.5 223.6 377.4 301.9 255.0 263.6 167.5 73.1 575.9 216.3 107.1 305.4 113.6 82.3 122.2 137.7 149.6 137.8 348.9 46.1 188.2 104.8 413.0 470.1 461.4 1032.4 556.2 201.8 186.6 149.9 490.1 91.4 650.8 146.5 118.9 290.5 131.0 311.9 117.5 139.5 116.3 136.6 183.2 124.2 114.6 123.3 164.6 194.6 538.9 136.8 148.5 112.7 119.0 120.8 121.2 162.8 120.3 132.4 119.9 119.6 121.5 118.1 120.7 131.6 116.7 6.4 30.5 9.1 131.8 813.2 199.3 238.8 139.5 56.9 122.9 189.0 32.9 64.3 89.8 130.6 35.5 136.6 166.9 111.7 283.7 202.8 128.9 78.6 142.8 110.6 151.9 195.7 11.5 170.7 161.9 130.2 58.1 98.9 238.0 78.9 92.1 96.4 298.5 63.9 10.8 120.4 142.4 152.4 462.0 85.7 179.3 208.1 247.3 14.0 241.9 79.9 286.3 11.6 22.9 289.9 126.2 173.0 131.7 423.3 144.8 257.8 54.4 47.9 92.1 90.1 194.1 131.0 171.1 163.8 1015.8 174.4 197.2 107.1 125.0 425.3 DUS2 "DUS2L, FLJ20399, SMM1" ENSG00000167264 "Dihydrouridine synthase 2" Q9NX74 16 67987746-68079320 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Oxidoreductase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 118.1;Late spermatids: 94.1;Spermatocytes: 53.1;Syncytiotrophoblasts: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042560, HPA043528" Enhanced Enhanced Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA042560: AB_10965170, HPA043528: AB_10959753" "unprognostic (2.21e-1)" "unprognostic (5.06e-2)" "unprognostic (1.91e-1)" "unprognostic (1.23e-2)" "unprognostic (8.12e-2)" "unprognostic (1.63e-2)" "unprognostic (1.23e-2)" "unprognostic (9.84e-2)" "unprognostic (2.36e-1)" "unprognostic (2.34e-1)" "unprognostic (1.53e-1)" "unprognostic (3.18e-1)" "prognostic favorable (3.50e-5)" "unprognostic (1.44e-2)" "unprognostic (8.05e-2)" "unprognostic (1.58e-1)" "unprognostic (1.81e-1)" 5.8 6.8 5.2 12.6 5.8 9.6 5.8 6.8 7.5 6.1 4.6 8.6 5.7 5.3 4.9 12.2 5.1 5.5 6.1 5.3 6.1 5.9 9.2 6.8 18.8 6.8 5.8 4.8 4.4 7.5 4.9 9.9 6.6 5.4 8.4 5.3 5.9 5.0 9.6 10.8 10.4 7.9 5.0 15.9 6.4 27.5 6.4 7.6 5.4 8.9 20.2 7.0 7.4 7.8 17.1 25.5 11.0 17.1 8.8 14.8 20.4 16.1 15.6 33.4 23.7 27.5 29.9 39.7 14.3 17.0 9.8 22.8 26.6 28.5 25.5 6.1 16.0 13.4 15.6 20.6 14.9 15.1 18.4 14.5 21.9 27.5 26.8 12.8 21.3 29.9 16.1 6.5 16.0 24.9 16.0 22.5 12.2 16.9 13.5 26.8 12.5 28.3 18.4 11.8 13.0 11.3 31.8 12.3 7.1 14.1 25.1 8.4 11.7 14.8 13.3 12.9 13.6 18.4 24.5 36.6 10.6 19.7 8.8 12.1 29.2 89.9 9.5 25.8 9.2 56.9 6.5 10.3 21.9 48.4 9.4 8.5 27.8 21.3 37.7 8.6 13.5 17.2 5.2 5.8 6.8 7.5 5.3 6.1 6.8 5.8 6.6 5.0 6.4 7.8 2.5 9.6 4.6 6.8 17.1 2.7 2.0 12.8 4.6 3.9 2.4 2.2 2.6 4.3 6.2 7.3 8.4 29.2 6.0 5.7 5.9 10.4 118.1 1.7 3.5 5.3 4.2 3.0 7.2 5.4 17.3 3.8 4.6 2.6 7.0 7.2 9.3 7.9 13.4 15.2 8.0 5.5 6.1 11.9 2.3 94.1 3.7 6.2 3.6 2.8 13.5 4.5 9.2 5.5 7.3 9.5 3.6 7.9 7.7 3.4 4.2 10.8 4.1 2.9 6.6 3.4 4.7 53.1 15.0 5.2 2.6 61.4 4.2 10.0 6.0 2.1 DUS4L "DUS4, PP35" ENSG00000105865 "Dihydrouridine synthase 4 like" O95620 7 107563484-107578523 "Predicted intracellular proteins" "tRNA processing" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044301 Approved Approved Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA044301: AB_10967460" "unprognostic (7.95e-2)" "unprognostic (1.95e-1)" "unprognostic (1.33e-1)" "unprognostic (5.66e-2)" "unprognostic (1.82e-2)" "unprognostic (1.19e-1)" "unprognostic (1.28e-1)" "unprognostic (1.46e-1)" "unprognostic (1.03e-1)" "unprognostic (1.35e-2)" "unprognostic (1.98e-1)" "unprognostic (3.00e-2)" "unprognostic (2.56e-3)" "unprognostic (2.29e-2)" "unprognostic (9.21e-3)" "unprognostic (7.74e-3)" "unprognostic (6.72e-3)" 1.5 1.9 1.1 0.5 1.2 0.4 1.5 1.2 1.5 1.6 0.9 1.4 0.6 1.5 1.7 1.7 1.3 0.6 2.7 1.1 1.2 2.7 2.0 1.0 0.8 1.2 1.2 1.8 1.7 1.2 1.5 0.6 1.3 1.5 0.8 1.0 1.6 0.5 1.7 1.5 1.3 0.5 1.2 1.3 1.6 2.3 1.1 0.7 1.6 1.1 0.8 1.7 1.5 1.4 4.1 1.6 1.6 1.0 0.5 1.0 2.3 0.9 1.4 1.7 1.5 2.1 3.6 4.6 2.1 0.6 4.6 1.2 1.7 2.4 2.3 1.2 1.3 1.2 0.9 2.6 1.6 3.0 0.2 1.2 3.5 1.6 5.7 1.8 2.4 3.9 5.4 1.7 2.7 3.0 4.3 5.8 2.8 3.3 3.4 2.3 1.7 5.3 3.2 2.1 1.6 4.4 1.9 4.2 3.6 2.3 1.9 2.6 1.7 2.5 2.0 1.8 2.6 3.0 3.8 4.9 2.3 4.3 2.9 0.0 0.1 0.0 0.1 0.2 0.2 0.2 0.4 0.1 0.2 0.1 0.3 0.4 0.0 0.1 0.1 0.1 0.2 0.1 1.1 1.2 1.2 1.5 1.1 1.2 1.2 1.2 1.3 1.2 1.1 1.4 4.5 6.4 3.9 4.6 7.6 5.1 11.0 5.6 10.2 10.0 8.6 10.2 9.2 5.7 6.6 11.0 4.2 9.1 4.5 3.3 7.9 13.3 32.8 11.3 7.2 4.6 9.6 5.0 3.5 16.2 8.8 4.6 5.1 11.0 13.4 10.2 4.2 9.3 6.7 3.3 5.1 5.0 10.2 5.0 3.7 24.9 4.4 5.6 3.6 5.6 5.2 15.4 11.3 4.5 9.7 15.7 6.8 3.8 5.6 8.1 7.7 17.3 15.3 9.8 13.1 3.4 5.7 12.4 11.0 11.2 4.0 3.7 6.7 7.6 6.3 6.9 DUS4L-BCAP29 ENSG00000288558 "DUS4L-BCAP29 readthrough" Q9UHQ4 7 107563971-107623317 "Predicted membrane proteins, Transporters" "Apoptosis, ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.8" "Group enriched" "Detected in many" 5 "granulocytes: 5.8;monocytes: 1.5" "Cell line enhanced" "Detected in all" "U-87 MG: 18.7" "HPA029215, HPA044301, HPA049694" Approved Approved Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" Cytosol "HPA029215: AB_10602331, HPA044301: AB_10967460, HPA049694: AB_2680854" 3.4 2.0 6.7 2.0 7.7 2.9 2.8 7.4 11.4 4.0 4.5 2.6 1.2 4.2 2.0 2.1 1.7 1.3 3.3 7.6 6.3 2.0 2.5 3.9 1.3 6.9 6.5 2.1 0.8 2.4 1.7 7.0 2.0 3.4 3.3 0.8 2.5 5.7 5.8 1.3 3.6 6.7 2.1 1.5 2.4 7.0 1.9 4.3 4.9 1.9 2.0 7.8 7.2 2.8 4.0 1.3 3.0 4.9 1.3 5.7 6.1 4.6 2.9 2.2 3.6 1.9 3.5 5.8 2.1 2.4 3.1 5.1 5.5 2.4 4.3 5.0 2.5 2.0 4.6 6.7 3.2 2.9 3.0 7.4 2.7 5.2 7.2 3.3 7.6 1.8 6.0 3.0 4.9 7.1 2.2 1.7 3.0 3.1 4.4 6.1 5.3 2.0 1.2 6.1 5.3 5.1 4.9 2.1 1.5 6.5 8.8 9.1 2.3 11.0 13.2 2.4 5.0 3.3 18.7 6.3 5.3 5.8 0.4 1.0 0.3 1.1 0.4 0.3 0.4 0.6 0.8 0.5 0.3 0.6 0.0 0.3 1.5 0.5 0.7 0.3 6.7 7.7 7.4 11.4 7.6 6.3 6.9 6.5 7.0 6.7 7.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DUSP8 "C11orf81, FLJ42958, HB5, HVH-5" ENSG00000184545 "Dual specificity phosphatase 8" Q13202 11 1554051-1572271 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 25.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 113.6;Distal enterocytes: 57.8;Glandular and luminal cells: 65.6;Horizontal cells: 90.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 2.5;SCLC-21H: 1.4;SH-SY5Y: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020071 Approved Approved Cytosol NA NA "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 56: Bipolar cells - Visual perception" Cytosol "HPA020071: AB_1847903" "unprognostic (2.29e-1)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "unprognostic (4.00e-2)" "unprognostic (1.35e-1)" "unprognostic (7.58e-3)" "unprognostic (6.08e-2)" "unprognostic (1.11e-1)" "unprognostic (1.44e-3)" "unprognostic (1.81e-1)" "unprognostic (4.04e-3)" "unprognostic (1.82e-1)" "prognostic favorable (2.75e-6)" "unprognostic (1.51e-1)" "unprognostic (1.57e-1)" "unprognostic (8.65e-2)" "unprognostic (6.30e-2)" 6.6 2.1 3.5 0.2 3.0 1.0 6.0 0.3 8.1 5.1 0.0 11.3 0.0 8.4 0.6 1.4 8.7 0.5 17.0 5.0 0.1 5.4 3.6 9.5 0.3 1.9 0.4 2.4 15.7 0.2 25.5 0.1 0.1 5.1 0.3 1.6 6.1 0.2 13.3 4.3 6.8 1.2 0.3 3.1 8.3 3.1 0.7 0.2 3.7 0.0 0.1 3.6 4.2 2.0 0.6 0.3 0.4 0.0 0.0 0.0 1.1 0.1 0.4 0.1 0.6 0.6 0.0 0.0 0.2 0.1 0.0 0.9 0.0 0.1 0.3 1.1 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 2.5 0.0 0.1 0.1 0.0 0.7 0.0 0.0 0.3 0.0 0.0 1.4 1.7 0.1 0.2 0.3 0.0 0.1 0.0 0.0 0.1 0.8 0.3 0.8 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.0 0.3 8.1 5.0 0.1 1.9 0.4 0.1 0.3 0.7 2.0 14.9 3.2 1.1 0.0 6.3 9.8 8.1 2.7 2.8 113.6 32.1 24.3 6.0 14.3 3.2 12.9 47.9 0.3 11.1 57.8 1.9 7.7 0.3 31.5 24.7 6.5 42.3 0.0 11.1 11.3 0.5 4.3 8.6 65.6 0.0 0.4 1.4 0.6 0.5 90.9 11.3 32.6 6.1 0.0 3.4 0.2 0.6 4.7 5.4 2.8 1.0 22.3 1.0 3.0 5.2 11.0 22.4 0.4 4.7 17.4 19.1 1.6 2.8 35.5 6.6 8.0 15.1 0.8 0.6 2.2 4.8 5.9 10.5 0.7 25.0 14.2 DYNC2I2 "bA216B9.3, CFAP133, DIC5, FAP133, MGC20486, WDR34" ENSG00000119333 "Dynein 2 intermediate chain 2" Q96EX3 9 128633653-128656847 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 20.4;Cytotrophoblasts: 89.8;Extravillous trophoblasts: 95.3;Hofbauer cells: 21.9;Syncytiotrophoblasts: 37.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 35.8;naive B-cell: 52.9" "Lineage enriched" "Detected in all" 5 "B-cells: 52.9" "Cell line enhanced" "Detected in all" "MCF7: 432.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040764, HPA041091" Approved Approved Cytosol NA Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 71: Testis - DNA repair" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "HPA040764: AB_10795625, HPA041091: AB_10796237" "unprognostic (1.45e-1)" "prognostic favorable (1.63e-4)" "unprognostic (2.55e-1)" "prognostic favorable (7.01e-5)" "unprognostic (2.27e-1)" "unprognostic (7.00e-3)" "prognostic unfavorable (8.79e-4)" "unprognostic (6.04e-2)" "unprognostic (4.39e-1)" "unprognostic (3.65e-1)" "unprognostic (8.55e-2)" "unprognostic (1.04e-1)" "unprognostic (3.57e-3)" "unprognostic (2.06e-2)" "unprognostic (1.68e-1)" "unprognostic (1.12e-1)" "unprognostic (1.28e-1)" 14.4 49.9 15.7 11.4 15.4 33.2 20.1 14.3 20.1 28.2 30.5 26.7 22.2 22.4 8.9 37.9 30.5 11.1 41.4 15.4 18.9 61.8 39.1 25.1 12.0 17.0 19.4 19.1 36.7 21.2 36.1 11.0 16.4 31.0 10.3 4.5 31.9 14.0 11.1 24.0 27.7 6.3 16.5 23.6 26.3 69.8 16.6 23.8 55.6 4.3 9.5 19.2 23.7 14.7 112.7 202.8 49.8 78.8 11.4 16.1 141.4 46.2 32.9 66.5 42.8 96.6 197.3 40.4 32.4 30.8 62.0 169.4 47.5 50.8 16.6 93.5 40.1 24.0 134.8 52.0 13.9 41.5 39.4 8.0 25.0 66.3 18.9 24.0 46.5 112.6 83.5 34.0 36.4 432.4 151.3 106.1 63.7 97.3 121.0 157.2 66.6 136.8 42.1 36.0 125.1 100.1 143.9 135.9 36.8 13.7 230.5 40.7 28.3 75.9 114.8 95.6 90.7 34.6 100.7 39.6 71.4 41.9 74.0 1.7 1.1 0.4 1.4 1.6 2.3 35.8 2.9 3.9 2.8 52.9 1.1 1.7 0.8 4.5 5.7 11.0 5.7 3.8 15.7 15.4 14.3 20.1 15.4 18.9 17.0 19.4 16.4 16.5 16.6 14.7 2.7 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 89.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 95.3 6.0 0.0 0.0 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 37.4 0.2 0.0 0.0 0.0 DYNC2LI1 "CGI-60, D2LIC, DKFZP564A033, LIC3" ENSG00000138036 "Dynein cytoplasmic 2 light intermediate chain 1" Q8TCX1 2 43774039-43810010 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein, Motor protein" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 197.5;Respiratory ciliated cells: 133.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 14.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 110.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062905 Approved Supported Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA062905: AB_2684899" "unprognostic (3.46e-1)" "unprognostic (3.25e-1)" "unprognostic (1.75e-1)" "unprognostic (2.49e-2)" "unprognostic (2.89e-2)" "unprognostic (4.05e-2)" "unprognostic (1.84e-3)" "unprognostic (9.85e-2)" "unprognostic (2.87e-2)" "unprognostic (1.22e-1)" "unprognostic (1.85e-2)" "unprognostic (1.91e-1)" "prognostic favorable (2.73e-5)" "unprognostic (1.06e-1)" "unprognostic (1.48e-2)" "unprognostic (4.32e-2)" "unprognostic (4.60e-2)" 16.2 23.2 20.2 7.5 21.3 6.8 32.6 16.1 23.6 28.3 34.9 15.4 19.0 35.6 46.6 11.0 53.4 20.7 15.5 20.0 21.9 50.2 13.4 23.4 10.2 20.4 19.3 39.7 16.2 42.2 31.2 13.6 18.7 20.8 17.9 44.0 16.3 20.0 10.2 15.8 16.3 19.8 17.9 11.0 17.1 44.9 21.3 10.8 34.3 8.5 9.7 15.0 13.9 20.6 21.2 12.0 20.5 13.1 32.5 64.5 17.6 11.5 24.8 13.3 12.4 4.0 14.4 12.0 24.8 15.2 17.0 13.8 9.9 16.5 15.4 15.4 21.1 9.4 5.5 15.3 31.3 18.7 14.8 38.3 23.4 26.5 12.1 40.6 18.5 14.1 29.0 5.6 18.7 10.8 9.2 20.6 9.4 27.3 12.0 12.2 19.0 3.8 110.1 18.0 14.0 25.1 13.0 7.1 15.5 19.4 19.7 16.9 13.1 11.6 10.5 14.4 9.8 21.0 12.3 3.0 25.8 4.7 12.6 14.8 2.3 2.1 1.7 3.9 1.8 3.7 2.2 2.4 3.1 2.1 2.7 2.3 0.8 2.6 3.1 1.8 1.4 1.4 20.2 21.3 16.1 23.6 20.0 21.9 20.4 19.3 18.7 17.9 21.3 20.6 11.9 19.2 16.8 58.1 6.4 9.7 18.2 42.9 7.4 21.7 19.3 22.4 13.9 21.5 31.3 53.3 29.2 19.7 2.3 10.2 90.1 21.7 197.5 71.7 42.2 8.1 12.7 5.5 96.8 22.0 9.1 27.8 15.3 24.2 17.7 26.2 14.6 7.3 12.4 16.8 64.9 20.3 50.8 4.5 5.3 39.4 33.2 5.9 23.2 22.5 3.3 29.3 4.1 33.7 43.4 14.5 32.1 33.8 4.7 9.6 52.4 84.1 133.8 36.9 19.7 14.8 14.8 102.1 15.9 9.1 9.1 9.3 4.9 30.1 17.5 12.8 DYNLT2B "MGC33212, TCTEX1D2" ENSG00000213123 "Dynein light chain Tctex-type 2B" Q8WW35 3 196291219-196318299 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 5.5;Cardiomyocytes: 6.2;Cytotrophoblasts: 29.4;Extravillous trophoblasts: 9.9;Hofbauer cells: 16.8;Syncytiotrophoblasts: 6.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "B-cells: 21.9;dendritic cells: 16.2;T-cells: 25.1" "Cell line enhanced" "Detected in many" "T-47d: 101.7" HPA049555 Approved Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA049555: AB_2680816" "unprognostic (1.16e-1)" "prognostic favorable (7.83e-4)" "unprognostic (5.34e-2)" "unprognostic (1.59e-2)" "unprognostic (1.47e-1)" "unprognostic (5.63e-2)" "unprognostic (2.65e-2)" "unprognostic (4.61e-1)" "unprognostic (9.98e-3)" "unprognostic (3.99e-2)" "unprognostic (3.44e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (6.23e-4)" "unprognostic (3.73e-2)" "unprognostic (1.05e-1)" "unprognostic (1.39e-1)" "unprognostic (2.32e-1)" 5.0 7.9 15.2 4.5 15.7 5.1 6.5 14.6 18.6 8.7 15.0 9.1 3.4 7.1 7.9 13.0 36.2 5.1 6.3 15.2 16.0 16.9 2.3 7.0 8.8 15.2 16.8 7.3 5.1 7.9 13.8 3.1 17.0 7.0 4.2 15.0 5.2 3.9 3.0 8.4 4.0 3.7 15.7 4.3 5.0 30.9 16.6 14.7 10.1 1.5 6.0 6.7 9.4 15.0 33.1 23.9 45.3 28.0 11.1 22.3 5.4 13.8 9.3 16.8 18.8 7.9 45.0 21.0 23.0 12.1 7.0 33.7 17.8 14.5 16.3 18.4 13.3 8.6 22.3 3.4 12.7 6.4 0.9 12.1 38.2 14.7 17.1 30.5 10.2 44.0 13.3 10.8 32.6 79.0 28.9 29.4 29.6 36.6 41.5 37.3 7.7 8.7 38.9 13.4 50.9 39.7 29.2 17.2 28.0 18.7 101.7 18.3 19.2 15.0 5.8 6.1 18.0 16.9 38.0 48.8 45.0 11.4 25.8 0.0 3.1 1.4 11.7 1.2 7.1 21.9 13.9 9.0 8.8 13.7 9.1 9.4 1.8 4.6 0.8 16.2 25.1 6.3 15.2 15.7 14.6 18.6 15.2 16.0 15.2 16.8 17.0 15.7 16.6 15.0 5.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 29.4 2.2 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 9.9 3.3 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 6.2 0.5 0.0 0.0 0.0 EDN2 ET2 ENSG00000127129 "Endothelin 2" P20800 1 41478775-41484683 "Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 26.1;esophagus: 20.8;vagina: 32.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 239.7;Basal respiratory cells: 137.3;Club cells: 146.1;Collecting duct cells: 69.9;Prostatic glandular cells: 62.5;Proximal enterocytes: 91.7" "Cancer enhanced" "Detected in many" "cervical cancer: 24.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.8;EFO-21: 35.9;HeLa: 13.0;SCLC-21H: 16.8;SK-BR-3: 41.2;U-2 OS: 15.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA028459 Uncertain Approved Cytosol "Secreted to blood" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 38: EFO-21 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA028459: AB_10602490" "unprognostic (2.71e-2)" "unprognostic (5.64e-2)" "unprognostic (8.39e-2)" "prognostic unfavorable (2.85e-4)" "unprognostic (1.47e-2)" "unprognostic (3.87e-1)" "unprognostic (2.66e-2)" "unprognostic (1.04e-1)" "unprognostic (5.44e-2)" "unprognostic (5.61e-2)" "prognostic unfavorable (5.81e-4)" "unprognostic (5.59e-2)" "unprognostic (1.28e-2)" "unprognostic (8.47e-2)" "unprognostic (1.76e-1)" "unprognostic (6.14e-2)" "unprognostic (3.85e-1)" 0.3 0.1 0.0 0.0 0.0 0.1 3.1 0.0 0.0 26.1 1.0 1.9 3.9 3.1 4.7 20.8 1.6 0.2 1.4 0.1 0.0 7.4 1.2 3.7 0.0 0.1 0.1 0.1 2.4 0.0 2.1 0.0 0.1 7.5 0.9 0.2 8.0 0.5 0.2 15.0 17.4 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.5 0.0 0.3 2.4 32.7 0.1 0.2 0.8 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.8 13.8 0.0 35.9 0.0 0.0 1.7 0.0 0.1 0.0 4.2 0.0 0.0 13.0 0.1 0.0 0.0 0.0 0.0 3.7 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.3 0.0 0.8 0.4 0.0 0.0 1.3 8.4 9.4 0.9 16.8 0.0 0.3 41.2 0.0 0.9 0.8 0.0 0.0 0.0 15.9 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 6.4 1.5 0.0 0.0 30.3 239.7 137.3 8.6 0.1 2.5 1.3 0.7 2.8 146.1 69.9 0.0 0.2 0.1 23.3 0.0 8.8 0.0 36.9 0.5 0.6 1.8 0.0 0.0 1.0 0.0 1.8 3.1 6.5 0.0 0.3 0.0 0.2 0.0 0.0 0.0 4.2 38.7 0.0 0.4 0.0 0.0 2.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 10.9 2.7 0.0 0.1 62.5 91.7 1.6 20.9 0.0 0.0 0.4 3.5 0.0 0.2 2.4 29.1 0.0 0.7 0.8 8.2 45.2 EEF1A1 "EE1A1, EEF1A, EF1A, LENG7" ENSG00000156508 "Eukaryotic translation elongation factor 1 alpha 1" P68104 6 73489308-73525587 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis, Transcription, Transcription regulation" "Elongation factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051759, HPA053862, HPA056990" Supported Supported Cytosol NA NA 82000000 "Cluster 30: Non-specific - Translation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Cytosol "HPA051759: AB_2681595, HPA053862: AB_2797248, HPA056990: AB_2683302" "unprognostic (6.47e-2)" "unprognostic (7.86e-3)" "unprognostic (2.53e-2)" "unprognostic (9.64e-2)" "unprognostic (1.39e-2)" "unprognostic (1.08e-1)" "prognostic unfavorable (5.57e-4)" "unprognostic (3.13e-1)" "unprognostic (1.61e-1)" "unprognostic (2.77e-1)" "unprognostic (1.41e-1)" "unprognostic (3.47e-1)" "unprognostic (8.61e-2)" "unprognostic (1.65e-1)" "unprognostic (8.00e-2)" "unprognostic (2.04e-1)" "unprognostic (7.73e-2)" 7265.1 5743.3 2531.3 4576.8 2717.1 10489.1 10504.6 2524.2 2783.1 7953.2 2902.2 6991.5 4783.5 7397.5 7203.8 6302.2 9034.9 4902.1 4074.6 2309.3 2687.4 7520.3 6459.1 4891.3 8813.5 2792.2 2572.6 12627.2 10370.0 6942.9 3776.4 5545.3 2828.4 5639.5 6936.4 2200.9 8381.0 6045.9 1682.1 7151.8 5076.6 7695.8 2980.6 5912.7 5776.4 1701.2 2687.7 8091.2 8348.4 1938.8 11294.9 6993.4 6470.3 2900.2 5218.1 8235.8 8697.0 13940.8 18183.0 32963.3 7874.7 7061.7 21384.2 10632.9 10044.2 12591.7 8020.5 20786.6 9976.7 13824.2 6089.1 5849.1 11729.0 15249.9 9969.0 3868.8 7099.6 7824.7 6142.2 13619.5 14708.8 15773.6 9201.9 26454.1 27514.4 7357.6 24803.6 17437.1 14783.4 8434.8 15242.2 7357.1 13131.5 8385.7 7184.5 17411.3 10348.2 6259.3 4400.0 14212.5 15389.7 26105.5 12201.5 14719.8 8337.9 8853.1 3931.6 10026.7 17535.8 9067.6 6928.7 24671.0 11535.0 4637.5 6195.9 3343.0 9206.4 7296.2 6913.1 5011.8 4780.9 12625.1 7404.1 2888.1 8472.3 895.8 7474.9 7600.7 14243.9 10580.7 12006.0 10174.3 8618.3 8426.8 13912.6 12049.7 681.7 9555.0 7680.9 6461.2 9278.5 26796.5 2531.3 2717.1 2524.2 2783.1 2309.3 2687.4 2792.2 2572.6 2828.4 2980.6 2687.7 2900.2 4915.6 3169.9 6059.2 107.4 11291.6 9829.9 12187.6 10417.5 11667.5 978.9 10528.4 9476.3 160.6 6258.2 5739.8 2637.3 546.3 9401.2 8653.6 2189.4 10344.0 5796.3 1373.9 4535.2 6754.2 5952.7 3862.8 6396.8 84.5 10404.1 12700.2 5756.1 4472.5 5831.2 3736.3 5732.4 6124.7 3323.0 6415.2 494.6 109.3 6969.3 3289.7 7779.7 8970.1 2325.8 8931.5 6705.0 5112.0 175.2 18016.6 3733.0 8468.7 76.9 162.0 7231.8 5821.6 7213.5 6811.7 11638.2 7494.7 14215.0 2974.6 1469.9 3536.8 7040.7 7075.1 1092.8 703.6 12784.4 10055.1 11086.8 9616.5 6982.9 8574.9 16180.0 EEF1AKNMT "CGI-01, DFNM1, FEAT, KIAA0859, METTL13" ENSG00000010165 "EEF1A lysine and N-terminal methyltransferase" Q8N6R0 1 171781660-171814023 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 8.1;Cytotrophoblasts: 16.9;Extravillous trophoblasts: 22.3;Hofbauer cells: 17.5;Syncytiotrophoblasts: 9.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044498, HPA053705" Approved Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA044498: AB_10960884, HPA053705: AB_2682235" "unprognostic (1.05e-2)" "unprognostic (3.68e-2)" "unprognostic (8.30e-2)" "unprognostic (2.76e-1)" "unprognostic (3.78e-1)" "unprognostic (4.40e-1)" "prognostic unfavorable (5.68e-4)" "unprognostic (1.86e-1)" "unprognostic (3.12e-1)" "unprognostic (8.83e-2)" "unprognostic (1.16e-1)" "unprognostic (3.65e-1)" "unprognostic (4.12e-1)" "unprognostic (6.86e-3)" "unprognostic (7.49e-2)" "unprognostic (3.01e-1)" "unprognostic (1.13e-1)" 10.5 12.6 8.0 11.3 8.6 8.2 11.1 9.4 8.3 10.5 8.2 10.7 12.1 10.2 18.6 9.8 12.1 7.1 9.4 7.8 8.4 10.0 10.4 9.6 13.8 9.1 8.3 11.0 10.0 10.6 5.4 9.0 8.3 9.4 11.4 6.2 10.2 10.4 16.4 11.2 11.2 11.5 8.7 11.3 10.0 13.0 8.9 13.2 9.3 13.1 14.2 10.1 8.5 9.2 27.3 63.3 16.7 17.2 23.1 20.7 44.7 33.5 26.2 39.5 30.7 48.2 27.5 49.5 39.3 22.9 26.0 27.3 51.3 26.8 31.2 32.4 29.1 34.3 33.0 21.3 17.0 46.2 33.4 18.5 24.5 41.1 17.7 18.1 23.9 26.6 69.7 16.6 30.3 20.7 36.9 31.3 63.6 54.0 84.1 33.3 21.9 45.8 22.7 27.7 27.3 37.5 25.3 56.8 31.0 40.3 42.0 39.8 19.8 26.6 24.4 27.6 40.0 42.7 51.2 56.7 20.2 31.5 24.5 1.6 8.0 3.0 8.3 7.7 9.6 8.4 8.3 7.1 7.7 6.1 7.4 10.0 2.3 10.5 7.1 8.9 6.7 7.5 8.0 8.6 9.4 8.3 7.8 8.4 9.1 8.3 8.3 8.7 8.9 9.2 1.6 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 16.9 1.9 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 22.3 3.0 0.0 0.0 0.0 0.0 0.0 0.0 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 9.6 0.3 0.0 0.0 0.0 EFHD2 MGC4342 ENSG00000142634 "EF-hand domain family member D2" Q96C19 1 15409888-15430339 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 372.4;NK-cells: 416.1;Pancreatic endocrine cells: 481.2;Urothelial cells: 431.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 133.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A-431: 370.3" "Low region specificity" "Detected in all" HPA048961 Enhanced Approved Cytosol No No 220000 "Cluster 1: Neutrophils - Mixed function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA048961: AB_2680572" "unprognostic (1.37e-3)" "unprognostic (3.69e-1)" "unprognostic (7.83e-2)" "unprognostic (4.44e-2)" "unprognostic (2.35e-1)" "unprognostic (3.82e-2)" "unprognostic (4.59e-2)" "prognostic unfavorable (5.57e-4)" "unprognostic (9.11e-2)" "unprognostic (9.61e-2)" "unprognostic (1.64e-1)" "unprognostic (1.71e-1)" "prognostic unfavorable (6.31e-9)" "unprognostic (2.71e-2)" "unprognostic (9.71e-2)" "prognostic favorable (2.70e-4)" "prognostic favorable (3.60e-5)" 37.7 78.9 52.5 77.7 56.8 174.3 27.5 31.6 76.9 32.8 20.4 74.3 83.3 33.7 5.9 58.7 29.3 32.9 28.5 75.4 34.9 23.0 33.3 60.0 46.3 100.2 31.4 26.9 75.7 10.7 28.6 21.4 101.7 44.6 29.6 2.7 27.3 19.0 6.4 35.9 96.4 17.3 29.6 140.0 92.0 95.2 36.1 25.2 41.6 4.9 29.5 62.6 40.5 62.9 370.3 91.8 8.8 23.8 14.1 30.0 46.8 46.0 43.4 42.7 40.5 35.5 98.8 79.6 141.6 32.1 54.8 88.1 24.5 80.9 27.0 99.8 47.8 19.1 21.6 57.4 22.5 98.1 160.1 23.9 27.2 87.0 21.9 19.9 55.5 35.5 46.4 37.6 26.6 36.8 50.8 188.6 11.6 50.1 112.9 67.2 82.1 63.4 25.3 76.2 20.1 15.6 40.5 34.3 76.8 6.9 15.1 104.8 105.4 62.5 66.9 196.7 74.8 25.4 63.8 34.9 87.4 193.2 86.8 16.3 33.8 52.5 44.0 34.4 12.7 3.9 9.8 20.9 29.5 4.2 4.6 18.0 133.2 28.5 30.0 10.3 7.6 17.0 52.5 56.8 31.6 76.9 75.4 34.9 100.2 31.4 101.7 29.6 36.1 62.9 54.2 3.2 12.2 5.9 44.1 66.2 123.7 25.2 26.7 1.8 21.3 23.0 7.2 32.9 24.4 22.0 10.4 23.7 372.4 280.0 19.6 69.6 93.6 55.4 28.8 52.6 61.7 28.0 33.9 259.4 222.8 31.1 157.0 69.4 44.5 49.4 23.6 20.9 219.3 0.0 21.9 160.8 24.4 217.1 188.2 221.2 9.9 246.9 23.2 13.1 171.3 4.9 416.1 0.5 3.7 481.2 190.5 6.8 62.9 112.2 305.8 28.1 25.7 5.0 46.0 26.7 28.5 5.4 5.7 48.9 68.5 53.4 120.1 178.3 117.8 431.4 EFL1 "EFTUD1, FAM42A, FLJ13119, HsT19294, RIA1" ENSG00000140598 "Elongation factor like GTPase 1" Q7Z2Z2 15 82130233-82262734 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Protein biosynthesis, Ribosome biogenesis" "Elongation factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 9.2;Glandular and luminal cells: 9.5;Granulosa cells: 16.0;Pancreatic endocrine cells: 9.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039654, HPA047110, HPA052345" Uncertain Approved Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA039654: AB_2676610, HPA047110: AB_2797233, HPA052345: AB_2681794" "unprognostic (2.53e-1)" "unprognostic (2.04e-1)" "unprognostic (9.92e-3)" "unprognostic (8.99e-2)" "unprognostic (1.84e-1)" "unprognostic (1.60e-1)" "unprognostic (2.64e-3)" "unprognostic (3.35e-1)" "unprognostic (1.14e-1)" "unprognostic (4.75e-3)" "unprognostic (3.56e-2)" "unprognostic (3.14e-1)" "prognostic favorable (1.50e-6)" "unprognostic (8.58e-2)" "unprognostic (2.96e-1)" "unprognostic (2.60e-1)" "unprognostic (7.05e-2)" 6.2 7.4 5.0 8.2 5.3 8.8 9.9 4.9 5.4 7.3 6.7 13.3 11.6 7.1 7.5 8.3 7.7 7.0 7.3 4.6 5.4 8.6 9.3 6.9 9.6 5.0 5.1 4.9 6.2 14.7 4.6 6.9 5.7 7.2 16.5 7.2 6.7 6.8 11.6 9.0 12.8 8.8 4.8 7.0 8.3 11.2 5.3 16.6 7.8 12.4 10.8 8.1 7.2 6.0 9.8 24.5 18.0 14.9 11.7 16.1 11.6 28.0 33.1 19.9 26.1 12.2 16.7 24.0 11.4 21.4 25.2 24.9 47.5 18.5 31.8 21.8 23.1 26.8 20.2 9.3 18.3 17.0 18.3 7.9 28.9 20.5 46.0 23.7 27.0 30.8 20.5 10.8 23.6 14.1 22.5 13.9 16.0 17.5 12.6 23.8 26.4 13.3 14.1 29.7 15.8 16.8 17.7 20.5 21.6 30.7 15.6 15.1 22.9 28.1 18.5 71.6 28.6 13.4 54.9 20.1 25.1 32.2 10.5 23.1 5.7 14.6 8.6 8.2 6.9 9.4 8.0 7.5 7.0 9.9 6.9 6.0 1.0 6.5 9.9 3.3 7.9 4.8 5.0 5.3 4.9 5.4 4.6 5.4 5.0 5.1 5.7 4.8 5.3 6.0 4.1 3.2 5.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 5.7 3.9 0.0 0.0 4.3 0.0 0.0 7.1 5.5 0.0 3.9 6.8 0.0 9.2 5.1 1.4 0.0 0.0 0.0 6.0 4.0 2.5 0.0 9.5 5.1 16.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 2.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.4 0.0 0.0 5.5 7.3 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 6.8 2.9 4.9 0.0 0.0 EGLN3 "HIFPH3, PHD3" ENSG00000129521 "Egl-9 family hypoxia inducible factor 3" Q9H6Z9 14 33924227-34462774 "Enzymes, Predicted intracellular proteins" "Apoptosis, DNA damage" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 110.3;skin 1: 118.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 213.7;Cardiomyocytes: 105.8;Distal enterocytes: 135.5;Extravillous trophoblasts: 115.9;Suprabasal keratinocytes: 231.6" "Cancer enhanced" "Detected in all" "renal cancer: 50.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 25.5" "Lineage enriched" "Detected in many" 14 "dendritic cells: 25.5" "Cell line enhanced" "Detected in many" "RH-30: 44.6;RPTEC TERT1: 38.2;RT4: 122.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064895 Supported Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "HPA064895: AB_2685384" "unprognostic (3.58e-2)" "unprognostic (4.76e-3)" "unprognostic (1.75e-1)" "unprognostic (8.87e-2)" "unprognostic (6.88e-2)" "unprognostic (1.38e-2)" "prognostic unfavorable (2.14e-5)" "unprognostic (1.39e-3)" "unprognostic (3.44e-2)" "unprognostic (1.79e-1)" "unprognostic (2.93e-2)" "unprognostic (2.90e-1)" "prognostic unfavorable (2.50e-4)" "unprognostic (1.37e-1)" "unprognostic (5.21e-2)" "unprognostic (4.71e-2)" "unprognostic (6.30e-2)" 14.6 0.8 32.9 9.4 40.9 0.3 10.0 38.2 37.5 12.3 15.4 25.9 35.7 10.0 4.4 27.0 9.4 13.8 110.3 29.7 38.9 16.3 4.9 8.3 5.7 34.3 37.5 2.1 4.3 0.3 3.4 25.4 32.2 9.1 20.0 15.2 11.2 12.0 20.8 118.2 40.9 11.7 31.9 4.9 37.7 1.1 42.9 4.9 2.8 6.4 9.8 51.3 20.8 36.1 31.1 8.0 0.9 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 8.2 0.0 10.0 0.1 0.9 0.9 15.0 29.4 0.0 3.1 8.0 8.3 20.5 1.0 0.0 0.0 0.4 4.0 14.5 0.0 0.1 0.0 0.0 2.3 16.9 0.0 0.4 2.7 0.7 0.1 24.3 26.7 2.8 0.0 44.6 11.1 38.2 122.9 6.2 7.0 2.0 11.8 3.2 18.2 12.0 0.1 0.0 0.2 3.2 0.0 1.8 0.4 6.7 0.1 7.2 0.0 0.5 0.0 0.0 1.8 0.1 0.0 0.0 0.0 1.2 0.9 2.6 0.0 0.1 0.1 0.1 1.1 0.0 25.5 0.0 0.9 32.9 40.9 38.2 37.5 29.7 38.9 34.3 37.5 32.2 31.9 42.9 36.1 6.0 0.0 0.6 36.2 1.6 213.7 49.0 56.6 3.4 11.6 16.0 17.0 105.8 4.3 24.8 9.2 2.1 11.4 16.0 135.5 9.8 15.6 1.8 42.3 8.5 25.1 16.2 0.4 1.0 6.9 115.9 16.8 74.9 17.2 1.3 0.1 12.5 0.3 3.1 1.7 4.3 31.6 12.2 1.9 62.8 4.9 2.5 10.8 40.9 0.0 0.9 11.6 0.0 6.6 54.2 46.6 41.9 0.7 0.4 17.4 59.7 20.5 37.2 2.4 0.0 17.7 9.4 1.7 0.3 4.1 231.6 103.0 4.5 1.2 14.1 25.7 EIF1AX "eIF-1A, eIF-4C, EIF1A, EIF4C" ENSG00000173674 "Eukaryotic translation initiation factor 1A X-linked" P47813 X 20124525-20141838 "Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002561 Uncertain Supported Approved Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA002561: AB_1078724" "unprognostic (1.91e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-2)" "unprognostic (9.69e-2)" "unprognostic (1.43e-2)" "unprognostic (1.26e-3)" "unprognostic (7.13e-3)" "unprognostic (2.22e-1)" "unprognostic (8.28e-2)" "unprognostic (1.02e-3)" "unprognostic (2.82e-2)" "unprognostic (4.73e-2)" "unprognostic (8.66e-2)" "unprognostic (2.23e-3)" "unprognostic (7.81e-2)" "unprognostic (1.61e-1)" "unprognostic (1.52e-1)" 61.2 42.9 27.1 47.9 29.2 61.6 58.2 36.8 38.3 45.1 23.0 46.5 43.9 57.9 28.5 49.7 42.2 26.7 47.4 27.9 29.3 58.0 62.0 35.0 44.5 29.3 28.9 66.9 50.6 46.6 19.8 40.1 28.3 36.2 31.6 45.3 49.9 30.8 80.0 42.1 37.3 49.6 32.2 33.7 45.7 30.4 30.4 41.4 48.4 50.4 33.9 42.6 49.2 35.7 233.3 128.4 96.9 129.8 92.5 124.8 78.8 202.6 73.9 108.3 84.9 186.2 108.2 215.5 132.2 134.9 101.4 97.6 172.8 175.9 167.8 88.8 284.5 95.7 148.9 160.1 64.5 257.8 129.5 59.1 105.2 167.4 260.2 71.4 153.3 68.9 252.3 117.6 107.9 113.2 160.3 160.6 252.1 97.5 211.0 129.8 222.3 232.0 85.1 127.7 112.1 124.9 215.0 165.8 139.0 138.8 134.6 108.0 88.3 130.8 81.6 430.8 153.6 79.9 163.3 255.7 89.5 116.1 101.2 36.3 41.0 27.4 47.8 46.5 64.1 69.0 54.4 57.2 41.2 66.4 62.6 52.8 10.7 64.5 47.1 68.1 47.6 52.6 27.1 29.2 36.8 38.3 27.9 29.3 29.3 28.9 28.3 32.2 30.4 35.7 205.4 105.8 116.7 22.2 167.5 474.9 354.9 172.6 178.2 164.0 226.5 212.2 100.2 161.5 154.5 115.8 93.8 191.4 231.5 131.6 187.9 213.6 450.5 210.5 310.1 161.2 167.2 135.2 40.5 230.4 453.8 208.6 107.6 321.9 164.0 140.7 137.4 329.9 196.3 102.6 43.2 213.5 120.1 137.9 230.1 132.2 144.1 157.3 154.7 35.6 118.2 181.3 68.0 23.6 48.0 251.0 140.1 145.2 176.7 469.7 152.2 301.4 93.2 140.4 144.7 288.6 213.9 52.9 101.1 245.4 570.1 227.0 170.5 149.6 288.5 377.0 EIF1AY ENSG00000198692 "Eukaryotic translation initiation factor 1A Y-linked" O14602 Y 20575776-20593154 "Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 121.3;tongue: 131.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 378.0;Erythroid cells: 538.5" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 7 "cerebral cortex: 34.9" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 180.2;HEL: 220.6;U-266/84: 161.1;U-698: 349.8" "Low region specificity" "Detected in all" HPA002561 Uncertain Supported Approved Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 6: Erythroid cells - Oxygen transport" Cytosol "HPA002561: AB_1078724" "unprognostic (4.31e-2)" "unprognostic (3.74e-1)" "unprognostic (2.14e-3)" "unprognostic (2.68e-2)" "unprognostic (1.12e-2)" "unprognostic (2.89e-2)" "unprognostic (4.18e-2)" "unprognostic (2.17e-2)" "unprognostic (4.10e-2)" "unprognostic (8.53e-3)" "unprognostic (2.89e-1)" "unprognostic (6.03e-2)" 17.4 22.2 3.3 11.4 3.6 59.8 14.6 3.6 34.9 0.0 3.5 20.8 14.6 0.0 20.6 14.8 0.0 8.9 121.3 3.2 4.4 26.2 25.3 14.9 9.7 4.2 4.4 0.0 13.7 13.3 27.8 16.2 4.3 26.9 25.2 11.6 13.7 20.2 85.2 11.7 28.9 0.0 3.6 31.9 16.5 21.4 3.6 0.0 11.3 131.5 27.7 18.4 0.0 4.6 0.5 26.4 0.0 0.0 0.0 0.0 52.7 57.4 39.1 39.5 39.1 0.0 0.1 180.2 0.2 32.0 0.0 0.0 0.0 0.0 55.0 97.4 0.0 220.6 0.0 65.8 38.4 0.4 0.0 21.1 44.2 0.0 0.0 0.0 0.0 59.4 0.3 0.0 65.1 0.0 144.7 0.2 37.8 0.0 0.0 0.0 70.9 71.9 56.5 67.6 50.1 0.1 0.1 0.3 42.4 71.9 0.0 30.9 56.8 29.9 0.9 0.3 63.1 103.9 161.1 349.8 11.6 0.1 0.0 48.8 20.4 28.3 14.2 21.8 19.7 53.2 25.9 16.8 16.7 55.3 31.2 25.2 125.8 21.6 22.1 66.2 31.7 21.5 3.3 3.6 3.6 34.9 3.2 4.4 4.2 4.4 4.3 3.6 3.6 4.6 0.0 32.1 49.9 2.9 122.1 54.7 68.5 123.8 26.7 19.6 0.0 0.0 378.0 35.8 63.3 53.3 10.4 123.0 51.8 6.8 88.0 47.7 59.6 0.0 0.0 31.3 17.8 538.5 2.0 0.4 45.6 33.1 27.5 0.1 91.7 0.0 57.8 16.5 38.9 6.7 2.4 23.3 61.1 67.9 43.7 16.7 42.9 43.0 67.6 1.0 88.7 92.2 59.8 3.0 2.5 21.5 9.6 43.6 101.2 63.3 28.9 123.6 64.2 26.3 39.5 23.5 31.7 85.0 90.4 29.9 50.6 92.8 48.3 0.0 18.8 73.2 EIF2AK2 "EIF2AK1, PKR, PPP1R83, PRKR" ENSG00000055332 "Eukaryotic translation initiation factor 2 alpha kinase 2" P19525 2 37099210-37157522 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003845, HPA019795, HPA063893" Approved Enhanced Cytosol NA NA 44000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB003845: AB_562332, HPA019795: AB_1848060, HPA063893: AB_2685144" "unprognostic (1.70e-2)" "unprognostic (2.26e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.77e-3)" "unprognostic (8.42e-2)" "unprognostic (8.02e-2)" "unprognostic (4.67e-2)" "prognostic unfavorable (2.08e-4)" "unprognostic (1.19e-1)" "unprognostic (3.15e-3)" "unprognostic (3.33e-1)" "unprognostic (1.74e-1)" "unprognostic (4.65e-2)" "unprognostic (5.32e-2)" 11.1 9.0 7.2 10.5 8.1 30.1 8.6 7.4 9.5 9.8 8.6 8.8 7.6 10.5 8.0 6.3 8.3 9.5 6.3 7.8 11.1 8.5 7.7 8.9 8.0 10.9 8.1 10.8 7.4 11.1 6.6 11.2 10.9 10.1 8.6 6.6 17.7 8.4 4.5 4.6 9.9 11.1 15.6 11.9 9.5 3.3 13.0 11.7 10.0 5.8 7.1 8.0 5.9 8.7 38.4 22.1 16.7 17.4 21.5 28.3 20.1 21.2 29.1 56.3 41.1 23.0 23.2 27.4 27.0 29.8 66.2 27.4 24.2 27.1 29.5 45.7 12.0 33.8 19.2 18.7 17.9 32.2 0.2 22.5 13.1 23.7 19.3 17.7 18.0 10.7 19.1 23.6 20.3 13.4 35.5 17.0 15.8 8.4 10.8 27.6 40.9 12.1 15.3 18.7 14.1 20.4 32.0 24.0 50.7 12.7 9.2 9.0 31.4 25.7 24.9 15.1 36.2 19.0 30.8 0.3 15.9 20.0 23.1 10.7 5.3 6.3 5.4 7.9 5.2 5.3 4.5 5.2 4.8 4.2 3.0 4.3 15.7 6.5 8.0 3.1 6.5 2.1 7.2 8.1 7.4 9.5 7.8 11.1 10.9 8.1 10.9 15.6 13.0 8.7 94.5 67.3 34.0 25.1 35.9 19.5 42.3 33.0 31.3 38.8 26.6 26.0 29.9 32.9 46.0 22.0 14.6 47.8 44.8 32.2 21.5 40.2 2.4 55.8 68.7 76.3 15.0 36.0 39.6 48.5 89.2 52.6 22.4 41.7 41.1 93.5 33.5 21.9 38.2 47.1 42.9 24.0 16.2 29.9 20.8 4.2 57.2 50.7 21.4 48.7 47.1 50.9 45.3 51.3 16.8 54.7 21.8 84.2 46.0 39.5 33.6 33.0 48.9 24.8 39.5 60.5 45.9 2.4 5.5 22.5 10.1 40.8 40.0 61.3 28.6 40.5 EIF2AK4 "GCN2, KIAA1338" ENSG00000128829 "Eukaryotic translation initiation factor 2 alpha kinase 4" Q9P2K8 15 39934115-40035591 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Activation of host autophagy by virus, Adaptive immunity, Antiviral defense, Cell cycle, Growth arrest, Host-virus interaction, Immunity, Neurogenesis, Stress response, Translation regulation" "Activator, Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase, tRNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 66.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011811 Approved Approved Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 15: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "HPA011811: AB_2668543" "unprognostic (3.10e-1)" "unprognostic (4.78e-3)" "unprognostic (5.97e-2)" "unprognostic (7.18e-2)" "unprognostic (1.05e-2)" "unprognostic (3.32e-2)" "unprognostic (1.18e-1)" "unprognostic (3.18e-1)" "unprognostic (1.36e-1)" "unprognostic (1.21e-1)" "unprognostic (1.38e-2)" "unprognostic (7.27e-2)" "unprognostic (2.38e-1)" "unprognostic (1.27e-2)" "unprognostic (6.47e-2)" "unprognostic (2.31e-2)" "unprognostic (5.11e-3)" 20.1 14.6 21.5 12.2 22.4 18.7 17.6 27.2 23.7 14.6 16.8 15.5 11.3 30.5 15.4 16.0 16.1 17.0 17.7 21.2 22.0 13.4 21.3 16.9 16.9 20.3 20.2 17.1 14.1 17.7 24.1 19.0 20.5 19.8 12.9 13.1 13.9 11.5 18.9 19.0 11.3 15.6 18.9 15.7 15.2 8.9 22.1 13.1 21.8 11.0 11.6 17.2 12.4 28.9 37.1 17.5 30.3 46.3 49.0 81.7 28.9 51.0 58.1 40.8 40.0 25.2 15.6 19.6 25.9 69.3 54.7 38.6 41.1 61.4 56.6 92.8 20.4 41.6 30.8 30.7 42.1 25.6 27.8 65.3 41.2 39.0 69.8 57.3 58.0 40.5 31.3 18.1 81.7 12.3 21.7 34.6 18.8 32.8 38.2 25.4 42.2 33.1 51.4 24.7 16.1 24.4 36.4 22.2 32.3 29.5 30.7 43.4 61.6 54.3 40.9 27.3 33.6 24.6 47.8 6.0 38.1 34.4 77.4 11.6 10.8 8.6 6.8 14.1 5.7 7.1 7.6 7.9 17.6 9.2 8.3 8.2 3.3 8.5 20.5 66.5 5.8 4.9 21.5 22.4 27.2 23.7 21.2 22.0 20.3 20.2 20.5 18.9 22.1 28.9 47.9 16.0 31.1 28.7 29.3 12.0 27.5 17.8 43.3 29.9 45.0 45.2 32.3 32.9 21.4 16.5 12.5 37.5 32.2 21.1 13.7 23.7 1.5 19.3 52.7 35.3 14.4 37.4 42.7 25.4 34.8 36.5 23.4 27.0 24.1 35.0 22.9 27.8 30.7 28.6 53.9 25.9 12.2 33.7 55.4 4.3 42.3 52.1 32.0 29.0 41.1 30.4 16.5 30.2 26.3 47.6 16.2 39.9 115.6 30.7 6.4 18.2 12.9 23.9 46.0 43.6 35.6 8.6 29.8 47.0 14.5 15.2 18.2 64.0 29.6 18.4 EIF2B1 "EIF-2B, EIF-2Balpha, EIF2B, EIF2BA" ENSG00000111361 "Eukaryotic translation initiation factor 2B subunit alpha" Q14232 12 123620406-123633766 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034258, HPA049509" Approved Approved Cytosol NA NA 16000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 50: Non-specific - Ribosome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "CAB034258: AB_2095995, HPA049509: AB_2680797" "unprognostic (2.14e-2)" "unprognostic (4.18e-2)" "unprognostic (2.78e-1)" "unprognostic (7.50e-2)" "unprognostic (1.22e-1)" "unprognostic (7.21e-2)" "prognostic unfavorable (6.75e-7)" "unprognostic (5.65e-2)" "unprognostic (7.24e-3)" "unprognostic (1.53e-1)" "unprognostic (7.27e-2)" "unprognostic (1.94e-2)" "prognostic unfavorable (1.78e-9)" "unprognostic (2.46e-1)" "unprognostic (3.74e-2)" "unprognostic (1.09e-1)" "unprognostic (9.40e-2)" 32.9 32.1 23.5 33.0 25.7 36.4 31.5 27.8 27.9 33.1 23.9 33.2 27.6 34.0 29.5 33.8 31.1 22.0 26.3 24.8 23.7 28.7 29.0 24.4 40.4 25.4 23.8 34.1 32.9 21.7 28.2 31.0 27.4 29.4 30.8 23.5 28.8 26.2 43.1 51.1 29.2 31.5 23.9 33.4 28.7 22.6 25.7 30.0 27.4 27.3 43.1 32.5 31.2 32.2 55.6 47.9 50.0 53.1 45.8 46.2 52.5 66.8 38.2 64.3 46.7 62.8 34.0 104.2 77.3 51.1 28.6 54.3 79.0 52.0 67.3 85.4 87.8 74.9 68.3 55.6 43.3 106.9 90.2 42.0 63.3 55.4 38.9 54.0 59.6 66.8 136.4 34.2 60.2 50.4 86.1 113.3 82.4 59.5 64.1 89.5 61.1 79.2 43.2 46.0 61.9 69.9 49.4 48.7 63.3 46.7 88.5 63.2 56.8 43.8 52.9 63.2 62.4 90.9 102.1 153.6 63.6 71.7 63.9 113.2 87.3 119.3 56.3 104.2 51.3 60.1 57.2 58.9 95.7 53.2 58.0 53.9 9.8 64.8 101.6 59.9 73.2 100.7 23.5 25.7 27.8 27.9 24.8 23.7 25.4 23.8 27.4 23.9 25.7 32.2 29.0 16.0 19.6 10.7 29.3 20.4 17.5 28.3 24.5 19.8 16.0 17.3 20.0 25.8 19.0 18.4 8.4 69.0 33.8 18.3 29.4 33.0 7.6 15.0 28.3 26.0 21.7 21.9 23.4 40.1 58.8 23.6 15.3 14.2 41.2 24.4 22.1 13.1 37.8 16.8 21.2 15.4 18.3 18.6 18.5 5.3 25.1 26.0 19.6 14.0 30.6 34.4 35.0 16.1 21.9 32.8 23.8 16.6 30.7 14.8 26.1 23.9 14.3 21.6 32.9 18.5 29.8 49.2 38.7 27.3 20.5 51.6 26.7 29.3 21.7 14.6 EIF2B5 "EIF-2B, EIF2Bepsilon" ENSG00000145191 "Eukaryotic translation initiation factor 2B subunit epsilon" Q13144 3 184135038-184146127 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015412, HPA064370, HPA069303" Approved Enhanced Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 59: Non-specific - Translation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "CAB015412: AB_831253, HPA064370: AB_2685249, HPA069303: AB_2686114" "unprognostic (3.28e-1)" "unprognostic (1.14e-2)" "unprognostic (9.05e-3)" "unprognostic (3.33e-2)" "unprognostic (1.15e-2)" "unprognostic (9.33e-2)" "prognostic unfavorable (3.38e-8)" "unprognostic (8.07e-2)" "unprognostic (1.32e-1)" "unprognostic (5.21e-2)" "unprognostic (3.80e-1)" "unprognostic (1.32e-2)" "unprognostic (9.97e-3)" "unprognostic (1.82e-1)" "unprognostic (1.01e-1)" "unprognostic (1.24e-1)" "unprognostic (5.32e-2)" 16.1 18.9 10.1 8.2 10.1 5.3 17.6 11.2 12.5 17.2 13.0 19.6 9.4 15.3 5.6 24.7 14.9 6.5 22.3 9.8 11.7 15.5 20.1 15.8 9.7 11.2 10.1 14.9 19.0 22.1 18.0 11.8 10.6 18.1 13.8 2.3 23.9 11.2 53.9 24.7 19.4 11.6 10.9 20.3 21.0 10.1 10.8 18.2 16.7 33.6 19.0 18.8 19.6 9.3 60.7 25.4 24.3 25.4 32.4 23.4 28.0 29.1 36.2 51.7 42.4 41.5 24.5 48.6 37.8 32.5 65.0 34.7 56.6 39.1 47.7 39.7 55.4 75.6 28.4 42.4 24.8 61.8 32.9 19.6 32.1 28.7 24.1 19.5 37.3 49.7 46.7 29.2 35.2 49.5 49.5 34.3 39.9 76.1 49.3 45.1 37.6 61.3 43.1 38.6 35.2 34.2 27.9 91.9 41.5 20.3 83.6 60.8 33.6 22.9 35.4 28.5 62.7 24.3 61.2 69.6 33.0 58.8 35.2 9.5 10.0 14.7 8.7 9.1 11.5 15.4 12.2 13.3 11.8 16.9 18.1 11.5 1.3 14.3 9.8 5.1 11.6 7.6 10.1 10.1 11.2 12.5 9.8 11.7 11.2 10.1 10.6 10.9 10.8 9.3 19.8 25.6 22.7 8.8 31.6 30.8 36.6 18.2 29.6 18.5 33.1 30.1 25.8 17.2 28.4 36.8 8.4 39.3 25.4 32.0 52.8 27.5 3.7 20.5 17.7 24.0 45.9 27.6 14.6 36.0 28.8 17.8 35.2 23.3 16.5 21.3 13.6 27.1 24.9 35.3 18.6 28.0 24.4 18.5 22.6 2.7 18.3 18.2 19.6 12.2 30.8 14.5 22.6 18.1 15.3 26.3 17.9 14.7 19.0 34.6 27.2 30.0 21.9 16.7 13.1 17.5 22.8 17.7 17.0 31.2 29.0 38.6 26.5 34.2 34.7 44.9 EIF2S1 "EIF-2alpha, EIF2, EIF2A" ENSG00000134001 "Eukaryotic translation initiation factor 2 subunit alpha" P05198 14 67360328-67386516 "Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis, Translation regulation" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011663, HPA064885" Supported Enhanced Cytosol NA NA 210000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB011663: AB_2096478, HPA064885: AB_2685382" "unprognostic (1.86e-2)" "unprognostic (8.33e-2)" "unprognostic (4.31e-2)" "unprognostic (2.46e-2)" "unprognostic (3.78e-2)" "unprognostic (1.78e-3)" "prognostic unfavorable (4.73e-7)" "unprognostic (4.14e-3)" "unprognostic (4.49e-1)" "unprognostic (1.68e-2)" "prognostic unfavorable (4.97e-4)" "unprognostic (2.95e-1)" "unprognostic (1.21e-2)" "unprognostic (1.73e-1)" "unprognostic (4.65e-1)" "unprognostic (1.59e-2)" "prognostic unfavorable (7.11e-4)" 28.3 24.5 12.5 29.9 14.0 25.0 25.7 15.1 17.8 18.1 10.4 25.0 21.5 19.4 19.6 38.8 15.8 21.5 28.7 14.6 14.1 24.5 35.3 18.4 30.4 13.7 12.7 17.1 26.3 22.9 9.4 26.3 13.6 22.1 26.7 21.2 18.3 22.3 49.4 23.7 21.5 27.0 13.8 19.8 19.8 33.4 13.5 27.9 27.9 40.6 33.5 39.1 19.0 16.6 265.7 86.4 59.8 92.3 56.4 63.4 127.8 115.5 68.3 127.4 110.7 101.6 92.2 118.7 57.0 87.4 85.7 100.4 139.1 110.3 192.7 86.9 51.9 76.9 80.0 70.4 59.2 82.7 71.9 52.4 62.6 113.9 172.5 49.8 105.4 73.8 132.6 89.6 127.3 131.3 113.7 64.7 61.1 157.9 142.9 85.7 99.0 84.6 78.2 120.0 85.9 60.7 83.0 96.5 91.1 52.3 164.5 70.8 81.3 167.4 180.7 82.0 124.4 77.0 90.4 180.7 97.1 145.3 110.2 51.4 50.6 33.0 47.4 71.0 58.4 55.4 54.5 51.7 70.1 45.8 50.3 51.5 6.9 58.6 62.8 48.0 64.3 70.7 12.5 14.0 15.1 17.8 14.6 14.1 13.7 12.7 13.6 13.8 13.5 16.6 64.1 28.9 40.2 17.3 44.1 142.8 88.2 77.2 37.5 22.1 32.0 30.1 92.8 30.0 55.8 22.0 12.5 78.7 38.0 23.3 70.5 89.6 81.0 34.6 48.9 60.3 13.1 64.2 21.7 63.0 104.7 51.2 34.1 44.8 35.5 35.7 26.4 39.8 70.4 37.0 20.9 30.6 61.1 37.9 51.3 33.4 31.1 40.7 51.6 15.9 61.3 32.2 36.0 15.1 23.8 70.8 18.3 40.6 56.7 79.9 26.6 65.1 35.0 35.2 26.3 60.7 85.9 204.9 96.3 49.7 130.4 93.4 46.1 57.9 39.7 79.1 EIF3C "eIF3-p110, EIF3S8" ENSG00000184110 "Eukaryotic translation initiation factor 3 subunit C" Q99613 16 28688558-28735727 "Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 67.3;Alveolar cells type 2: 101.4;Cardiomyocytes: 157.0;Club cells: 91.1;Respiratory ciliated cells: 168.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB034045, HPA047097, HPA049495, HPA050112" Supported Supported Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "CAB034045: AB_1122487, HPA047097: AB_2679930, HPA049495: AB_2680793, HPA050112: AB_2681020" "unprognostic (2.42e-1)" "unprognostic (2.69e-2)" "unprognostic (2.07e-1)" "unprognostic (2.18e-1)" "unprognostic (5.84e-2)" "unprognostic (1.23e-1)" "unprognostic (1.85e-2)" "unprognostic (5.75e-2)" "unprognostic (7.23e-2)" "unprognostic (1.40e-1)" "unprognostic (3.90e-2)" "unprognostic (6.54e-3)" "unprognostic (3.53e-3)" "unprognostic (2.25e-1)" "unprognostic (1.48e-1)" "unprognostic (6.42e-2)" "unprognostic (1.10e-3)" 174.0 99.7 86.7 113.5 94.3 149.8 185.7 77.4 92.6 136.9 83.2 189.7 148.6 138.0 51.7 159.7 185.9 86.7 135.3 98.1 89.2 172.8 143.1 104.6 124.8 87.4 91.6 236.4 219.6 227.9 86.8 122.8 92.8 115.2 166.1 94.8 187.6 112.9 360.1 188.3 145.0 149.0 80.2 116.2 124.4 140.8 84.2 91.0 175.7 291.9 189.0 144.8 104.2 89.3 182.1 321.5 419.3 481.5 368.0 453.1 627.7 444.1 380.9 587.7 425.4 620.6 333.9 461.7 556.7 322.2 366.5 214.5 361.4 618.1 650.0 188.4 376.0 518.9 466.8 860.4 471.9 791.3 344.6 521.4 367.4 370.4 582.8 253.6 679.5 439.3 595.7 394.5 314.5 783.0 622.0 299.2 652.8 304.0 491.2 638.8 612.7 447.0 317.8 406.4 379.1 573.2 396.8 531.0 478.0 263.3 551.6 356.6 570.3 372.3 370.1 180.4 299.9 325.8 279.0 860.7 378.7 320.4 398.7 54.5 198.1 90.2 122.0 204.0 140.6 114.3 131.8 129.1 213.2 113.9 127.4 120.5 14.3 163.8 220.5 98.3 147.2 267.3 86.7 94.3 77.4 92.6 98.1 89.2 87.4 91.6 92.8 80.2 84.2 89.3 5.0 67.3 101.4 1.0 9.6 11.9 10.0 3.9 15.4 7.0 5.3 3.0 157.0 5.7 91.1 5.5 41.7 3.7 6.2 4.6 1.9 3.3 2.8 8.7 7.7 16.0 6.0 17.5 1.4 3.5 3.1 33.2 10.2 12.9 39.1 7.3 7.9 4.8 3.1 0.0 1.5 5.9 2.0 5.0 8.4 3.5 6.5 12.6 5.4 5.6 3.9 1.9 2.1 4.5 1.0 4.1 5.2 5.3 21.4 5.7 7.1 5.2 168.1 16.2 0.0 6.9 18.5 3.9 4.6 16.9 13.8 5.6 11.2 6.1 6.3 8.8 EIF3CL ENSG00000205609 "Eukaryotic translation initiation factor 3 subunit C like" B5ME19 16 28379579-28403841 "Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 22.4;Alveolar cells type 2: 44.0;Cardiomyocytes: 35.1;Club cells: 37.9;Respiratory ciliated cells: 38.2" "Group enriched" "Detected in some" 5 "glioma: 0.8;ovarian cancer: 0.5;stomach cancer: 0.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "HPA047097, HPA049495, HPA050112" Supported Approved Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 50: Non-specific - Ribosome" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 11: Alveolar cells - Smell perception" Cytosol "HPA047097: AB_2679930, HPA049495: AB_2680793, HPA050112: AB_2681020" "unprognostic (1.22e-1)" "unprognostic (4.24e-2)" "unprognostic (2.40e-1)" "unprognostic (4.48e-3)" "unprognostic (1.98e-1)" "unprognostic (4.59e-2)" "unprognostic (1.75e-5)" "unprognostic (6.56e-2)" "unprognostic (1.64e-1)" "unprognostic (7.58e-2)" "unprognostic (1.48e-1)" "unprognostic (1.18e-3)" "unprognostic (3.59e-2)" "unprognostic (9.52e-2)" "unprognostic (1.41e-1)" "unprognostic (9.00e-3)" "unprognostic (3.58e-2)" 40.8 35.4 19.9 1.0 20.2 6.2 41.2 20.4 33.5 37.9 16.6 37.1 1.3 29.4 3.5 44.3 33.8 1.9 47.4 20.9 19.7 43.0 39.9 30.7 1.6 21.3 20.2 50.5 72.9 4.0 32.1 2.4 21.9 35.6 2.3 5.4 38.5 3.3 98.6 52.3 30.3 2.0 18.0 32.1 43.1 30.7 19.9 1.8 40.6 6.9 2.9 37.7 35.8 21.2 3.0 6.9 6.6 5.5 9.1 5.2 4.3 3.8 4.6 9.5 8.2 7.7 3.5 4.1 6.8 5.8 7.6 5.5 11.0 10.9 14.1 1.9 6.5 4.7 12.7 15.3 2.7 6.9 8.3 5.7 7.3 5.7 6.0 5.7 3.6 6.8 7.6 7.8 3.6 9.4 8.2 17.3 15.1 5.7 4.0 10.9 8.0 7.4 8.1 5.1 13.1 8.5 3.2 6.4 6.0 1.8 16.4 6.8 5.2 4.2 7.9 5.2 7.6 4.2 3.8 7.2 7.3 7.2 7.7 2.9 1.3 0.7 1.1 1.8 1.3 0.9 1.4 1.2 1.7 0.9 1.2 1.6 0.1 1.1 2.3 0.8 1.2 1.3 19.9 20.2 20.4 33.5 20.9 19.7 21.3 20.2 21.9 18.0 19.9 21.2 0.1 22.4 44.0 0.7 2.2 1.3 2.0 0.3 1.8 0.0 0.5 0.6 35.1 0.0 37.9 0.0 0.0 0.8 0.0 0.4 0.0 0.5 0.1 0.2 0.2 4.9 0.0 8.4 0.5 1.2 0.6 10.5 3.1 0.1 10.1 0.0 1.8 0.2 0.5 0.0 0.6 0.7 0.0 1.3 2.3 0.7 0.3 5.2 0.0 0.0 0.5 0.0 0.0 0.0 0.4 1.1 1.7 0.4 5.2 1.1 0.9 1.7 38.2 0.0 0.0 0.5 7.4 0.3 0.6 2.5 1.6 0.8 2.6 0.1 0.7 1.0 EIF3D "eIF3-p66, eIF3-zeta, EIF3S7" ENSG00000100353 "Eukaryotic translation initiation factor 3 subunit D" O15371 22 36510855-36529184 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045882, HPA063330, HPA066216" Approved Supported Cytosol NA NA 36000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA045882: AB_2679482, HPA063330: AB_2684988, HPA066216: AB_2685637" "unprognostic (4.98e-2)" "unprognostic (2.22e-1)" "unprognostic (8.74e-3)" "unprognostic (6.50e-3)" "unprognostic (1.39e-2)" "unprognostic (2.34e-3)" "prognostic unfavorable (8.10e-5)" "unprognostic (1.47e-1)" "unprognostic (2.58e-1)" "unprognostic (9.98e-2)" "unprognostic (5.54e-3)" "unprognostic (3.93e-2)" "unprognostic (5.49e-2)" "unprognostic (2.14e-2)" "unprognostic (1.72e-1)" "unprognostic (5.22e-2)" "unprognostic (9.78e-2)" 121.7 84.3 46.1 105.2 48.9 176.9 184.5 48.6 48.2 127.8 59.0 118.7 107.3 121.7 123.7 144.5 158.1 84.6 95.0 46.2 48.0 88.4 88.0 87.5 174.1 51.1 48.6 193.3 228.0 108.1 55.3 109.8 51.3 97.8 135.5 45.6 132.8 102.2 152.1 153.4 100.1 118.7 48.9 138.6 129.3 63.5 50.8 162.6 113.5 93.1 211.8 134.7 116.2 52.2 312.4 171.3 172.2 197.2 237.8 462.3 287.8 235.2 321.2 319.5 313.7 270.7 171.1 395.3 173.4 271.8 202.4 230.9 295.1 374.5 320.7 215.7 313.6 215.4 151.9 209.6 428.2 507.5 214.4 419.6 427.7 357.1 515.0 365.1 347.5 128.0 238.3 195.9 363.6 194.0 180.3 281.0 188.5 484.9 141.6 318.1 278.0 305.0 314.2 214.9 135.9 190.7 153.6 311.3 337.4 180.0 196.7 472.5 243.9 247.9 222.6 188.3 333.6 247.5 171.8 316.9 252.1 318.1 242.7 166.7 383.7 141.3 320.3 353.5 520.4 518.1 461.1 381.1 528.9 509.2 558.2 455.7 95.1 402.3 348.9 303.3 608.7 826.1 46.1 48.9 48.6 48.2 46.2 48.0 51.1 48.6 51.3 48.9 50.8 52.2 115.6 60.9 92.0 13.7 184.7 212.9 287.1 299.1 134.9 37.3 231.9 216.8 67.9 130.1 167.1 46.0 31.3 224.2 151.5 68.2 150.6 191.7 126.3 108.4 95.3 141.7 112.7 101.4 8.5 207.8 240.4 99.4 78.0 88.1 187.3 128.9 126.7 41.0 219.7 25.2 8.7 149.1 109.9 211.0 176.1 46.4 138.5 121.7 129.9 8.4 275.1 75.6 137.0 10.6 12.5 185.6 134.7 108.3 72.5 230.6 176.5 160.1 119.9 46.2 72.3 147.9 260.8 106.0 83.2 140.3 215.8 246.1 159.8 162.2 219.7 288.0 EIF3E "eIF3-p48, EIF3S6, INT6" ENSG00000104408 "Eukaryotic translation initiation factor 3 subunit E" P60228 8 108162787-108443496 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Initiation factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023973 Approved Supported Cytosol NA NA 21000 "Cluster 39: Non-specific - mRNA processing" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Cytosol "HPA023973: AB_1848083" "unprognostic (8.18e-2)" "unprognostic (4.28e-2)" "unprognostic (6.26e-2)" "unprognostic (1.51e-1)" "unprognostic (3.52e-3)" "unprognostic (6.93e-3)" "unprognostic (2.29e-2)" "unprognostic (2.57e-2)" "unprognostic (3.47e-1)" "unprognostic (1.96e-1)" "unprognostic (1.67e-3)" "unprognostic (3.63e-1)" "prognostic unfavorable (3.06e-7)" "unprognostic (2.46e-1)" "unprognostic (1.60e-1)" "unprognostic (1.81e-1)" "unprognostic (2.77e-2)" 269.0 201.4 104.7 94.2 107.2 251.7 418.1 113.6 178.1 360.4 110.9 281.2 93.5 232.5 243.3 256.3 263.0 163.5 187.7 104.6 110.0 178.0 199.1 174.2 231.1 107.7 108.9 449.4 409.1 138.5 157.2 161.1 111.2 204.8 155.7 63.6 214.1 186.4 343.2 230.9 181.7 135.6 107.3 157.6 237.0 83.9 107.6 283.0 183.9 241.1 208.9 248.7 267.2 112.7 339.4 208.1 211.3 193.3 518.2 1098.8 139.9 193.0 430.3 415.4 443.0 238.0 260.1 653.0 213.0 288.6 134.2 187.6 421.1 507.6 502.6 216.1 485.0 595.8 218.6 472.3 357.6 287.5 169.0 813.2 745.9 272.8 678.6 534.7 636.8 405.6 477.5 196.8 469.6 453.7 384.2 898.4 196.2 577.7 403.6 300.6 278.8 436.6 520.0 305.2 223.5 192.2 122.0 78.0 363.2 288.2 263.8 413.7 279.1 131.7 241.7 139.9 201.9 167.4 171.6 426.5 171.6 483.1 149.8 79.5 165.6 32.6 104.0 161.0 197.1 214.7 205.5 148.4 218.7 178.0 301.0 225.9 14.6 166.8 153.1 116.6 202.5 317.3 104.7 107.2 113.6 178.1 104.6 110.0 107.7 108.9 111.2 107.3 107.6 112.7 216.8 134.6 204.6 36.9 565.3 1036.0 1105.8 1174.4 805.3 64.5 569.8 274.2 93.1 317.4 463.5 158.2 54.2 614.4 288.0 101.3 606.5 332.3 377.4 173.8 399.2 365.6 297.5 319.8 36.3 354.3 770.9 366.9 196.7 220.5 378.3 277.1 403.4 212.6 424.2 58.9 36.2 400.5 443.5 662.4 875.2 73.8 454.2 368.7 517.6 37.5 621.8 154.8 268.8 59.8 69.2 272.3 279.1 327.6 251.0 728.2 273.8 799.7 201.7 74.6 190.7 434.6 564.5 276.7 102.8 532.6 1117.1 620.3 488.1 490.0 568.6 914.3 EIF3G "eIF3-delta, eIF3-p44, EIF3S4" ENSG00000130811 "Eukaryotic translation initiation factor 3 subunit G" O75821 19 10115014-10119918 "Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1509.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 1471.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041997 Approved Enhanced Cytosol NA NA 64000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 24: NB-4 - Immune response" "Cluster 32: Non-specific - Translation" Cytosol "HPA041997: AB_10804123" "unprognostic (1.80e-2)" "unprognostic (2.16e-2)" "unprognostic (9.00e-2)" "unprognostic (3.33e-2)" "unprognostic (2.22e-2)" "unprognostic (2.33e-2)" "unprognostic (2.55e-2)" "unprognostic (1.49e-1)" "unprognostic (1.73e-1)" "prognostic favorable (3.94e-4)" "unprognostic (4.90e-2)" "unprognostic (3.04e-1)" "unprognostic (1.98e-1)" "unprognostic (2.40e-2)" "unprognostic (7.63e-2)" "unprognostic (1.91e-1)" "unprognostic (2.43e-1)" 193.6 153.1 91.9 97.0 98.6 127.9 188.0 97.9 110.3 211.3 91.2 219.0 94.9 190.6 61.3 144.2 189.7 68.1 212.6 88.1 93.5 152.7 134.3 135.4 125.4 100.6 94.6 280.0 324.5 116.2 119.6 90.8 99.9 172.0 54.3 24.8 182.2 102.2 529.8 212.4 148.0 73.8 98.4 168.9 207.6 176.3 96.8 124.9 139.2 221.1 98.8 183.5 171.9 103.1 211.5 175.5 130.1 174.9 170.8 216.6 169.2 175.6 242.3 269.0 247.7 289.2 111.1 214.9 245.1 210.8 121.9 158.4 159.7 265.0 111.1 196.0 491.8 379.8 179.0 293.2 283.7 303.8 192.7 262.7 191.0 191.6 181.0 172.2 195.7 263.1 349.2 249.6 164.3 282.3 333.2 1471.2 323.1 131.9 372.0 265.3 129.2 287.2 173.4 181.8 170.0 328.9 117.6 152.0 287.9 73.2 133.4 264.4 196.1 233.0 132.6 256.1 339.1 726.8 567.8 240.2 175.6 328.5 227.9 199.9 319.1 139.5 267.6 238.7 348.0 244.5 287.0 291.8 303.2 255.3 287.5 262.4 60.3 458.6 200.3 240.7 351.5 457.0 91.9 98.6 97.9 110.3 88.1 93.5 100.6 94.6 99.9 98.4 96.8 103.1 183.9 44.8 94.5 7.2 219.3 228.2 271.7 185.8 191.2 41.5 276.0 342.9 43.3 164.5 118.1 108.5 18.8 470.9 273.6 146.4 187.9 182.7 438.1 99.7 141.5 160.6 129.9 131.1 4.2 309.1 328.2 159.1 122.3 108.9 129.3 197.3 167.4 98.9 225.1 21.9 4.1 231.1 81.4 288.5 268.9 1509.3 237.9 198.9 145.9 4.7 351.7 85.5 557.1 6.6 10.8 205.3 198.8 177.1 192.6 241.0 277.0 320.1 100.6 56.6 164.3 189.9 243.8 221.1 142.4 152.9 238.7 527.2 261.5 209.6 235.4 263.2 EIF3H "eIF3-gamma, eIF3-p40, EIF3S3" ENSG00000147677 "Eukaryotic translation initiation factor 3 subunit H" O15372 8 116642130-116766925 "Cancer-related genes, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 1808.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023117, HPA023553" Approved Approved Cytosol NA NA 38000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA023117: AB_1848076, HPA023553: AB_1848077" "prognostic unfavorable (5.26e-4)" "prognostic unfavorable (8.07e-4)" "unprognostic (1.81e-1)" "unprognostic (1.15e-1)" "unprognostic (6.69e-2)" "unprognostic (1.11e-2)" "prognostic unfavorable (8.34e-4)" "unprognostic (3.63e-2)" "unprognostic (1.37e-1)" "unprognostic (1.96e-1)" "unprognostic (1.12e-3)" "unprognostic (3.08e-1)" "unprognostic (3.77e-2)" "unprognostic (6.36e-2)" "unprognostic (1.48e-1)" "unprognostic (9.19e-2)" "unprognostic (1.11e-1)" 212.3 164.1 111.0 168.6 119.8 341.1 246.8 114.8 138.5 270.2 104.2 233.1 172.7 212.7 180.0 232.0 211.3 159.2 223.6 106.9 121.0 184.2 181.0 149.2 283.2 118.4 113.7 392.6 249.9 184.0 147.6 161.7 120.6 179.5 201.9 131.0 219.9 158.1 372.6 201.8 167.9 182.5 124.2 171.4 195.2 144.4 111.9 291.0 215.5 278.3 307.1 221.7 237.0 130.2 455.0 256.2 302.2 264.9 390.3 678.0 300.4 292.5 374.4 316.7 306.5 266.1 521.6 719.4 288.6 307.2 230.4 284.4 335.5 445.2 395.5 468.5 271.9 636.0 212.0 400.6 487.8 278.1 325.7 630.0 606.4 287.0 659.5 536.4 348.8 555.5 548.2 370.1 360.4 335.7 778.2 388.1 308.6 995.6 404.5 443.6 201.8 517.6 479.8 327.8 341.6 412.4 153.5 1808.1 504.9 294.8 538.3 550.5 322.5 201.8 374.5 301.5 388.8 591.3 574.4 591.3 280.2 483.4 281.8 165.2 361.6 132.2 217.9 356.8 358.9 438.1 393.5 317.9 468.6 381.4 511.0 432.1 74.4 314.6 366.1 260.9 477.7 585.7 111.0 119.8 114.8 138.5 106.9 121.0 118.4 113.7 120.6 124.2 111.9 130.2 138.9 182.7 210.7 42.4 314.6 337.5 423.7 444.2 266.9 62.7 317.2 273.4 160.8 191.6 253.0 93.8 12.5 488.0 211.4 117.0 448.0 290.5 387.2 81.2 196.0 185.8 201.0 215.8 47.8 380.5 551.0 183.7 125.9 159.2 194.4 166.2 168.8 104.6 332.4 26.9 49.9 301.6 170.9 386.6 402.8 265.0 331.5 261.5 209.9 51.5 509.9 136.0 224.6 58.3 70.3 292.9 240.5 220.1 166.7 338.5 260.2 443.9 92.9 76.8 197.2 251.5 504.1 233.0 176.0 317.4 356.5 577.2 287.5 241.4 345.5 481.2 EIF3I "eIF3-beta, eIF3-p36, EIF3S2, TRIP-1" ENSG00000084623 "Eukaryotic translation initiation factor 3 subunit I" Q13347 1 32221077-32245397 "Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA029939, HPA029940" Enhanced Approved Cytosol NA NA 70000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA029939: AB_10611109, HPA029940: AB_10600878" "unprognostic (4.48e-2)" "unprognostic (1.01e-1)" "unprognostic (7.82e-2)" "prognostic favorable (2.14e-4)" "unprognostic (3.86e-2)" "unprognostic (2.32e-2)" "prognostic unfavorable (4.21e-4)" "unprognostic (9.26e-2)" "unprognostic (1.28e-1)" "unprognostic (4.94e-2)" "unprognostic (1.00e-1)" "unprognostic (1.32e-1)" "prognostic unfavorable (4.81e-6)" "unprognostic (1.80e-1)" "unprognostic (2.93e-2)" "unprognostic (1.60e-1)" "unprognostic (8.47e-2)" 123.4 146.6 69.2 109.3 70.2 103.5 164.5 76.9 87.3 126.4 78.7 137.2 96.4 104.4 162.3 154.7 141.7 93.7 127.0 68.6 71.8 123.8 152.8 99.6 134.0 72.8 71.2 154.1 134.8 141.9 78.3 116.2 73.3 113.2 163.5 52.5 127.2 120.4 247.3 119.8 91.0 144.9 72.7 84.7 118.8 48.9 73.6 164.5 131.8 220.5 187.1 158.0 107.1 79.0 404.3 293.3 207.4 463.5 326.9 427.2 209.3 301.3 514.2 517.2 401.5 317.1 418.3 533.0 320.7 514.0 315.9 265.9 498.6 549.9 667.0 234.4 348.1 288.9 245.8 362.7 352.5 559.1 295.4 413.1 471.2 528.0 569.5 363.4 478.8 363.8 699.1 223.4 502.4 276.3 469.3 370.2 624.2 445.4 339.4 344.1 356.3 509.0 515.9 300.9 325.6 343.4 276.6 351.7 562.1 366.6 282.9 270.7 286.4 333.2 360.3 523.8 653.5 377.7 495.7 487.4 365.2 419.6 440.2 113.8 196.6 93.7 164.4 206.7 180.4 182.1 171.8 160.5 235.8 164.9 148.4 140.5 15.2 183.0 162.0 177.0 219.6 299.8 69.2 70.2 76.9 87.3 68.6 71.8 72.8 71.2 73.3 72.7 73.6 79.0 136.9 51.3 76.7 6.8 114.5 136.6 227.6 275.6 84.8 38.0 123.6 114.7 41.9 87.2 136.4 51.5 10.4 300.8 118.2 90.1 133.1 295.4 60.8 79.2 114.2 163.5 138.6 69.0 6.8 272.8 341.4 125.6 71.9 85.1 115.3 120.3 89.6 77.1 224.1 13.5 8.2 184.0 148.5 108.1 131.5 29.5 172.4 108.8 144.1 5.6 190.8 69.9 112.3 7.1 10.7 284.4 115.6 139.2 107.5 173.9 125.9 216.2 99.2 41.8 92.1 108.0 338.3 76.5 76.6 121.8 141.4 342.3 115.1 192.3 213.5 219.9 EIF3J "eIF3-alpha, eIF3-p35, EIF3S1" ENSG00000104131 "Eukaryotic translation initiation factor 3 subunit J" O75822 15 44537125-44563029 "Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 209.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050977 Approved Approved Cytosol NA NA 280000 "Cluster 6: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 16: U-266 - Nucleosome" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA050977: AB_2681297" "unprognostic (4.47e-2)" "unprognostic (1.28e-1)" "unprognostic (7.68e-2)" "unprognostic (3.76e-2)" "unprognostic (1.72e-3)" "unprognostic (1.47e-3)" "unprognostic (2.33e-2)" "unprognostic (1.41e-2)" "unprognostic (3.01e-3)" "unprognostic (8.31e-2)" "unprognostic (1.17e-3)" "unprognostic (4.52e-2)" "unprognostic (3.43e-3)" "unprognostic (1.39e-2)" "unprognostic (1.97e-1)" "unprognostic (4.76e-1)" "prognostic unfavorable (4.96e-5)" 48.2 34.2 40.0 40.8 42.3 38.7 39.9 41.5 51.7 26.8 34.7 36.2 36.2 26.8 30.8 48.8 22.0 26.1 40.1 39.8 45.0 46.4 58.7 25.8 38.9 44.6 47.9 22.3 65.5 34.9 22.9 44.8 46.1 32.3 37.1 21.2 56.3 29.8 209.6 37.1 31.4 35.5 41.0 30.5 35.3 31.6 44.4 34.0 35.9 104.0 49.8 49.6 31.6 47.0 103.5 55.7 88.4 55.5 60.7 60.0 113.1 161.0 46.9 108.5 72.9 165.6 59.6 96.0 184.6 67.1 102.5 192.3 137.7 99.5 129.5 114.5 79.8 222.5 129.4 108.6 115.1 239.2 98.4 54.6 130.7 72.8 141.6 65.1 117.2 111.1 294.9 119.8 97.8 73.1 124.0 160.8 55.4 190.5 92.9 141.2 145.4 146.1 122.4 118.0 118.4 74.9 150.6 137.1 89.7 69.3 118.0 196.6 140.3 117.6 140.7 127.9 216.4 145.5 302.4 244.8 80.9 249.0 114.0 64.3 40.3 40.7 35.6 41.6 40.8 59.2 45.9 43.7 46.8 53.4 44.1 47.5 18.3 60.4 40.7 76.7 52.9 13.1 40.0 42.3 41.5 51.7 39.8 45.0 44.6 47.9 46.1 41.0 44.4 47.0 92.8 60.9 54.6 16.3 93.1 175.1 112.6 86.5 49.5 56.2 174.6 114.2 95.2 108.7 79.7 145.3 20.9 148.7 122.8 148.0 193.7 145.2 149.7 118.6 141.0 92.2 117.3 139.5 22.0 149.6 170.8 69.2 50.0 175.5 127.4 73.1 99.2 404.3 110.7 43.7 24.1 172.9 61.1 98.7 106.6 103.4 91.0 78.5 60.5 18.7 108.5 50.1 109.2 16.6 27.4 152.3 118.6 71.1 91.9 119.0 94.9 266.4 43.1 66.8 46.0 74.1 94.3 205.4 153.4 70.6 172.0 247.1 88.5 54.7 180.6 102.8 EIF3K "ARG134, EIF3S12, HSPC029, M9, PLAC-24, PRO1474, PTD001" ENSG00000178982 "Eukaryotic translation initiation factor 3 subunit K" Q9UBQ5 19 38619082-38636955 "Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045446, HPA054590" Uncertain Supported Cytosol No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 21: OE19 - Mitochondria" "Cluster 32: Non-specific - Translation" Cytosol "HPA045446: AB_10962716, HPA054590: AB_2682534" "unprognostic (7.07e-3)" "prognostic favorable (1.31e-4)" "unprognostic (3.04e-2)" "unprognostic (2.10e-3)" "unprognostic (1.67e-2)" "unprognostic (3.16e-1)" "unprognostic (2.25e-2)" "unprognostic (3.17e-1)" "unprognostic (1.46e-1)" "unprognostic (7.06e-3)" "unprognostic (2.92e-2)" "unprognostic (4.26e-2)" "prognostic favorable (5.43e-4)" "unprognostic (1.82e-1)" "unprognostic (1.00e-1)" "unprognostic (6.49e-2)" "unprognostic (3.69e-2)" 233.4 177.9 98.8 83.6 100.4 172.7 228.3 104.9 114.2 214.3 113.1 285.5 142.0 186.6 110.2 286.1 188.4 73.2 591.7 98.9 100.9 313.3 189.0 169.3 142.0 103.2 101.7 214.8 262.2 179.6 173.0 72.0 101.0 172.1 165.7 57.9 197.5 100.4 682.7 290.7 219.1 113.7 102.1 222.5 265.7 66.5 103.7 143.7 168.6 462.4 182.1 218.4 216.6 105.3 135.3 421.3 110.1 175.4 196.5 197.7 134.3 104.2 180.7 220.9 192.5 272.0 118.6 300.2 121.2 174.2 128.7 122.4 221.2 280.8 165.1 145.7 184.6 214.0 134.4 197.2 201.0 345.1 170.7 219.6 252.3 151.4 269.6 118.8 242.3 156.6 217.9 250.8 188.8 215.2 185.3 158.6 103.5 474.4 211.4 222.7 197.0 235.7 225.3 311.0 141.5 139.4 114.8 377.1 174.0 117.3 145.9 260.3 133.9 135.0 134.8 81.3 185.9 246.4 276.3 255.6 114.9 321.6 155.0 154.8 267.8 138.2 182.8 297.8 232.1 252.0 222.3 213.2 359.0 218.0 228.9 204.0 72.4 201.2 305.7 209.4 296.4 441.8 98.8 100.4 104.9 114.2 98.9 100.9 103.2 101.7 101.0 102.1 103.7 105.3 372.1 93.0 166.1 26.4 430.3 395.6 547.4 674.4 345.4 83.6 477.2 755.1 502.5 320.3 331.0 217.0 66.7 422.9 376.3 466.2 1097.6 345.5 160.6 182.0 231.8 309.3 326.1 284.2 23.8 453.2 484.8 267.7 231.9 180.6 248.2 239.0 311.7 278.6 660.9 23.5 25.0 567.7 305.2 640.7 552.1 274.4 265.3 470.7 466.0 10.3 572.6 276.9 415.1 14.6 24.7 330.2 487.2 199.7 386.6 461.9 874.5 974.2 198.3 174.9 203.8 331.4 450.3 109.0 83.4 594.2 457.0 454.1 424.0 319.1 719.5 622.7 EIF3M "FLJ29030, GA17, hfl-B5, PCID1, TANGO7" ENSG00000149100 "Eukaryotic translation initiation factor 3 subunit M" Q7L2H7 11 32583798-32606264 "Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031063 Approved Approved Cytosol NA NA 130000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA031063: AB_10602128" "unprognostic (4.40e-2)" "unprognostic (1.47e-1)" "unprognostic (2.64e-2)" "unprognostic (7.16e-2)" "unprognostic (3.18e-1)" "unprognostic (4.10e-2)" "prognostic unfavorable (1.28e-9)" "unprognostic (5.79e-3)" "unprognostic (2.27e-2)" "unprognostic (1.83e-2)" "unprognostic (4.14e-3)" "unprognostic (1.91e-1)" "unprognostic (5.89e-2)" "unprognostic (2.12e-1)" "unprognostic (1.12e-1)" "unprognostic (1.10e-2)" "unprognostic (6.42e-2)" 96.9 105.0 49.5 72.4 53.0 141.4 135.1 51.9 71.6 89.6 51.1 80.6 77.1 96.5 106.6 95.0 146.4 70.8 86.1 52.0 56.1 112.7 108.4 60.1 122.7 52.3 49.5 162.9 131.6 64.7 49.4 79.8 51.5 71.3 98.4 43.3 78.6 82.3 103.1 102.5 60.2 98.3 52.7 71.1 88.0 74.3 51.7 131.2 107.6 82.4 146.6 113.6 79.5 55.9 173.6 219.0 171.0 218.8 222.7 318.2 251.5 176.1 242.7 264.5 255.6 284.5 124.1 445.6 118.1 201.6 226.7 214.1 301.1 319.4 328.2 151.4 372.3 201.2 164.5 303.4 322.1 473.9 276.4 287.4 355.1 178.8 434.6 221.5 301.3 234.6 403.8 151.2 293.8 204.1 238.3 494.4 188.4 230.8 334.2 192.0 430.7 209.9 291.4 321.4 131.3 203.0 125.2 233.5 279.9 187.0 259.3 279.6 142.1 164.6 188.0 353.0 540.2 183.5 248.8 324.0 148.2 284.3 166.1 71.9 211.7 65.7 99.7 189.3 137.6 144.9 136.9 127.3 258.4 117.9 141.1 129.9 24.8 142.3 142.8 154.8 156.5 186.0 49.5 53.0 51.9 71.6 52.0 56.1 52.3 49.5 51.5 52.7 51.7 55.9 82.7 83.3 66.4 19.2 147.5 212.9 256.2 372.8 189.0 44.7 112.9 132.3 41.1 81.5 168.0 60.7 20.9 261.8 127.8 47.1 131.0 187.3 154.9 76.4 168.8 106.3 72.4 148.5 23.8 250.7 284.0 121.9 103.0 104.3 158.4 123.6 98.6 73.3 197.1 10.1 23.5 132.3 156.6 250.6 209.6 55.2 133.9 153.6 110.3 12.2 283.6 70.0 131.8 20.1 21.6 171.8 87.4 120.4 132.4 212.0 86.3 220.6 87.6 42.5 72.3 140.1 254.9 109.4 72.6 159.5 225.0 243.0 154.1 228.3 169.9 252.9 EIF4A1 "DDX2A, EIF-4A, EIF4A" ENSG00000161960 "Eukaryotic translation initiation factor 4A1" P60842 17 7572824-7579006 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Helicase, Hydrolase, Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1342.5;Basal respiratory cells: 1913.6;Langerhans cells: 1330.1;Suprabasal keratinocytes: 1233.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011689, HPA068286" Uncertain Approved Cytosol NA NA 4100000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB011689: AB_732122, HPA068286: AB_2685968" "unprognostic (1.49e-2)" "unprognostic (2.41e-1)" "unprognostic (8.00e-2)" "unprognostic (2.17e-1)" "unprognostic (2.49e-1)" "unprognostic (2.12e-3)" "unprognostic (7.25e-2)" "unprognostic (2.89e-2)" "unprognostic (2.72e-2)" "unprognostic (2.11e-2)" "unprognostic (2.65e-2)" "unprognostic (5.19e-3)" "prognostic unfavorable (1.76e-8)" "unprognostic (1.91e-1)" "unprognostic (5.96e-2)" "unprognostic (1.16e-1)" "unprognostic (1.13e-2)" 500.5 373.3 110.2 296.5 113.4 416.2 354.2 118.1 129.6 287.0 116.7 260.6 199.7 290.3 196.6 566.2 307.9 229.5 229.7 112.7 123.9 274.2 328.3 339.0 286.3 128.9 119.1 302.8 360.5 150.4 190.2 301.9 125.9 219.2 289.5 118.5 268.6 168.7 281.2 375.5 228.9 316.6 122.9 291.4 313.2 159.8 131.2 309.3 171.4 122.4 385.2 506.9 321.6 131.5 1048.3 1396.3 914.1 833.9 802.7 931.9 852.4 977.9 1104.0 1770.4 1356.8 1420.1 457.7 1428.7 735.7 1032.2 774.7 907.6 1962.5 1505.4 1890.2 468.1 1454.0 799.3 854.7 1597.9 1226.2 826.4 771.9 1244.8 763.3 1491.8 1510.3 1055.1 1351.6 784.4 831.1 284.9 1294.2 1092.6 865.0 704.8 789.1 1068.6 952.6 802.1 691.1 682.2 1249.8 939.1 481.2 934.2 883.0 585.6 1273.8 679.4 651.5 625.1 976.1 930.2 649.9 603.8 2010.9 276.0 425.7 921.2 1000.8 999.3 1045.7 318.5 1639.1 408.1 463.4 1377.5 755.2 469.1 493.1 497.9 1905.9 412.2 477.7 488.1 157.1 658.5 1076.3 727.7 682.0 2945.6 110.2 113.4 118.1 129.6 112.7 123.9 128.9 119.1 125.9 122.9 131.2 131.5 212.3 115.4 239.6 0.0 139.7 1342.5 678.5 1913.6 173.0 113.5 191.0 183.4 6.8 104.4 799.6 73.5 116.7 345.6 185.8 100.5 152.6 295.4 32.4 120.7 171.6 286.1 116.1 139.6 0.0 231.4 370.5 299.2 129.5 165.0 149.1 237.5 154.2 63.8 212.1 106.0 0.0 117.3 767.0 160.4 1330.1 42.0 160.9 206.7 725.7 0.0 133.3 120.7 119.4 0.0 0.0 313.9 123.3 109.1 134.7 342.8 151.8 174.0 446.1 119.4 151.2 374.4 871.4 71.5 102.8 154.0 1233.4 636.9 224.2 197.1 135.9 474.6 EIF4A2 "BM-010, DDX2B, EIF4A, EIF4F" ENSG00000156976 "Eukaryotic translation initiation factor 4A2" Q14240 3 186783205-186789897 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Helicase, Hydrolase, Initiation factor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011690, HPA068286" Uncertain Approved Cytosol NA NA 1600000 "Cluster 44: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB011690: AB_732123, HPA068286: AB_2685968" "unprognostic (1.49e-1)" "unprognostic (9.62e-2)" "unprognostic (3.78e-2)" "unprognostic (9.50e-3)" "unprognostic (2.82e-2)" "unprognostic (1.10e-2)" "unprognostic (4.46e-2)" "unprognostic (6.27e-2)" "unprognostic (4.32e-3)" "unprognostic (1.00e-1)" "unprognostic (6.39e-2)" "unprognostic (3.99e-2)" "unprognostic (6.36e-2)" "unprognostic (3.22e-1)" "unprognostic (3.03e-1)" "unprognostic (4.67e-2)" "unprognostic (2.62e-2)" 178.4 288.5 277.5 105.8 302.9 7.3 243.4 328.0 388.2 274.5 251.6 282.5 143.3 325.0 196.3 178.1 322.0 205.3 383.9 309.0 331.3 287.8 202.6 156.2 192.3 275.4 254.5 606.8 272.1 189.2 292.5 218.8 290.2 249.7 179.7 310.3 213.5 262.9 675.3 93.7 165.7 252.8 270.6 159.0 196.0 155.3 316.9 178.0 293.8 553.2 170.0 224.3 186.8 275.6 95.4 44.6 179.1 30.2 624.9 589.3 59.3 158.9 138.5 159.1 202.1 159.9 34.2 200.0 812.8 213.7 283.4 146.8 255.2 66.5 272.0 182.6 134.8 304.8 54.4 214.5 249.6 68.3 209.0 402.5 291.8 47.8 368.3 764.1 275.2 161.6 109.6 311.9 496.8 14.2 112.5 31.2 183.7 337.0 199.4 143.3 124.1 122.2 305.9 110.4 331.8 71.9 241.4 175.4 356.9 427.3 269.6 244.3 205.6 122.8 63.0 123.9 87.7 252.1 374.8 85.9 86.9 71.0 63.9 233.4 78.5 88.5 125.8 87.5 200.8 245.4 183.2 154.5 91.0 203.0 273.4 224.2 50.5 169.6 125.3 85.4 187.3 282.3 277.5 302.9 328.0 388.2 309.0 331.3 275.4 254.5 290.2 270.6 316.9 275.6 265.3 118.6 220.2 68.6 416.9 690.3 770.9 595.8 412.6 267.4 396.7 308.2 271.3 327.5 447.9 261.1 64.6 450.1 370.8 306.7 661.2 254.3 33.0 287.9 297.5 319.2 407.8 221.4 146.8 94.5 251.2 367.8 250.2 344.2 312.1 267.2 258.1 142.4 226.6 390.3 138.0 372.9 455.7 228.6 385.2 56.8 385.8 242.9 345.1 92.8 318.1 383.9 256.4 73.9 118.7 136.0 410.8 472.8 235.7 737.4 567.9 665.2 337.8 192.8 236.7 409.7 489.9 223.8 165.4 314.8 618.0 615.5 449.2 345.6 380.1 879.5 EIF4B ENSG00000063046 "Eukaryotic translation initiation factor 4B" P23588 12 53006282-53042215 "Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039072, HPA046164" Approved Enhanced Cytosol NA NA 340000 "Cluster 32: T-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 32: Non-specific - Translation" Cytosol "HPA039072: AB_2676333, HPA046164: AB_2679567" "unprognostic (1.91e-2)" "unprognostic (2.63e-2)" "unprognostic (4.50e-1)" "unprognostic (2.47e-1)" "unprognostic (1.29e-1)" "unprognostic (1.17e-1)" "unprognostic (6.41e-2)" "unprognostic (2.68e-1)" "unprognostic (1.55e-2)" "unprognostic (2.83e-2)" "unprognostic (1.43e-1)" "unprognostic (2.17e-1)" "unprognostic (1.55e-3)" "unprognostic (3.44e-1)" "unprognostic (3.57e-1)" "unprognostic (4.69e-1)" "unprognostic (8.20e-3)" 181.5 173.3 92.3 137.5 110.4 226.6 251.5 117.5 100.2 222.2 111.1 167.1 192.4 251.8 135.3 165.1 270.5 165.7 179.4 79.9 103.3 200.1 218.2 135.3 233.6 108.0 95.4 637.4 278.8 202.8 90.7 155.5 112.3 152.5 173.0 114.5 262.7 142.3 510.5 178.1 161.6 177.2 120.4 177.9 163.1 80.2 103.2 287.9 233.9 361.4 293.2 186.8 148.3 116.4 214.9 341.1 233.9 296.6 416.3 787.8 300.6 204.0 492.1 188.9 170.8 352.0 340.4 1318.2 296.3 311.4 160.4 234.2 420.0 460.4 238.3 256.6 244.3 503.4 450.6 401.5 320.0 723.3 282.4 787.1 473.2 219.2 682.1 1144.5 377.1 385.9 561.1 515.8 319.6 468.0 443.5 488.4 438.3 232.9 178.6 447.7 321.9 558.8 267.8 347.1 238.8 326.7 213.7 456.4 432.2 298.9 521.9 485.3 339.6 128.6 272.0 142.8 184.6 450.2 529.3 330.0 219.3 318.7 180.7 40.8 76.2 40.8 105.0 79.0 152.5 96.1 126.9 116.3 94.9 69.9 159.2 148.3 19.7 100.0 97.9 61.3 114.2 146.9 92.3 110.4 117.5 100.2 79.9 103.3 108.0 95.4 112.3 120.4 103.2 116.4 140.5 147.4 227.1 20.2 283.6 207.9 244.9 179.3 270.4 86.8 246.1 177.4 144.2 215.9 166.5 93.8 31.3 139.7 220.6 108.7 181.9 131.7 242.5 120.6 186.1 168.5 186.3 209.4 33.0 174.6 244.5 145.4 154.5 124.8 235.5 201.5 208.1 211.3 109.4 63.9 35.5 188.0 71.2 276.1 185.3 638.6 202.3 182.9 140.5 18.7 254.0 127.0 178.2 22.6 37.7 129.2 117.6 195.6 227.5 214.8 204.1 257.6 121.6 85.5 111.7 205.1 160.7 79.6 48.6 281.3 235.8 178.7 243.3 203.7 234.0 244.0 EIF4G1 "EIF4F, EIF4G, p220, PARK18" ENSG00000114867 "Eukaryotic translation initiation factor 4 gamma 1" Q04637 3 184314495-184335358 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis, Translation regulation" "Initiation factor, RNA-binding, Translational shunt" "Cancer-related genes, Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 348.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014774, HPA028487, HPA043866" Approved Enhanced Cytosol NA NA 330000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB014774: , HPA028487: AB_10602219, HPA043866: AB_2678705" "unprognostic (4.14e-3)" "unprognostic (2.10e-2)" "unprognostic (6.01e-2)" "unprognostic (3.01e-2)" "unprognostic (2.25e-1)" "unprognostic (2.41e-3)" "prognostic unfavorable (7.99e-4)" "unprognostic (4.27e-3)" "unprognostic (2.35e-1)" "unprognostic (1.54e-1)" "unprognostic (1.55e-3)" "unprognostic (7.06e-3)" "unprognostic (2.42e-1)" "unprognostic (7.15e-2)" "unprognostic (2.45e-1)" "unprognostic (1.31e-1)" "unprognostic (2.33e-3)" 86.2 91.8 24.8 75.7 22.2 84.0 69.0 17.9 22.2 66.6 34.1 81.8 62.0 71.3 32.7 126.8 59.6 50.9 90.8 23.3 29.8 53.9 113.0 74.2 55.7 38.5 36.1 57.5 96.2 99.3 57.4 59.4 32.4 62.2 56.5 22.3 93.1 59.2 348.3 116.7 67.2 74.7 24.4 58.2 79.9 64.8 37.4 49.1 71.3 177.0 63.2 76.0 85.3 16.6 559.0 232.3 173.1 205.7 196.9 192.5 322.5 298.6 204.1 315.4 238.8 486.5 173.7 348.4 381.9 367.6 358.5 292.7 322.6 365.8 230.5 375.1 345.8 321.3 226.1 206.4 173.4 321.4 212.2 199.6 206.8 292.4 268.8 152.8 278.3 128.8 239.6 267.2 205.7 403.4 219.7 105.3 368.9 241.3 180.8 221.7 183.4 281.9 156.8 331.8 197.7 174.6 258.1 415.6 187.6 144.6 445.2 206.5 364.1 227.2 228.9 297.3 567.9 203.8 263.2 629.0 260.5 271.4 258.3 8.3 16.0 6.7 11.7 14.4 10.8 7.7 7.8 9.6 12.8 9.2 6.9 7.6 5.6 8.7 21.0 18.1 6.0 12.7 24.8 22.2 17.9 22.2 23.3 29.8 38.5 36.1 32.4 24.4 37.4 16.6 63.9 76.9 72.6 23.8 41.7 59.1 78.2 58.0 70.6 24.2 69.3 46.2 109.4 50.1 72.3 62.5 14.6 64.0 37.6 135.5 13.7 98.8 151.6 53.0 67.1 69.3 55.7 82.7 10.8 135.3 74.8 64.5 75.4 85.6 48.0 163.8 43.5 152.8 66.8 21.9 12.9 97.2 50.8 40.8 39.9 202.7 73.0 48.9 33.8 14.0 53.0 23.2 30.9 4.0 10.1 149.0 69.0 56.1 112.9 96.8 77.0 45.4 51.4 23.2 78.9 81.6 78.9 24.8 41.4 120.7 91.8 79.6 46.0 94.8 108.4 95.6 EIF4G2 "DAP5, NAT1, p97" ENSG00000110321 "Eukaryotic translation initiation factor 4 gamma 2" P78344 11 10797050-10808940 "Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis, Translation regulation" "Initiation factor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005163, HPA006773, HPA016965" Approved Enhanced Cytosol NA NA 48000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB005163: AB_638994, HPA006773: AB_1848099, HPA016965: AB_1848100" "unprognostic (1.10e-2)" "unprognostic (1.57e-1)" "unprognostic (1.15e-1)" "unprognostic (1.34e-1)" "unprognostic (9.92e-2)" "unprognostic (2.52e-1)" "prognostic unfavorable (6.18e-5)" "unprognostic (1.25e-1)" "unprognostic (7.84e-3)" "unprognostic (5.42e-2)" "unprognostic (7.07e-2)" "unprognostic (2.63e-1)" "prognostic favorable (1.67e-4)" "unprognostic (1.02e-2)" "unprognostic (2.08e-1)" "unprognostic (6.16e-2)" "unprognostic (2.74e-1)" 307.1 259.9 177.4 278.4 178.0 516.4 213.7 182.9 197.9 281.1 260.2 329.2 217.0 310.5 310.1 372.0 265.0 290.0 377.9 165.0 195.9 321.8 288.7 312.8 286.6 190.0 226.5 247.1 259.6 368.6 160.2 406.4 196.9 276.2 318.6 258.5 231.1 305.5 456.4 299.5 216.3 395.9 186.5 249.5 245.4 226.4 193.0 384.8 349.7 372.4 369.3 430.0 203.0 191.1 933.5 715.1 958.4 527.9 668.2 712.0 668.4 848.9 841.7 713.1 483.6 790.1 1064.3 525.7 474.1 1029.4 545.2 537.8 1048.1 781.0 970.8 820.1 489.0 676.3 427.7 607.2 580.2 1041.8 545.9 582.3 601.0 444.6 577.3 657.1 830.2 483.5 527.8 570.5 935.1 481.8 691.7 377.9 702.1 646.8 756.0 690.3 563.8 336.1 630.7 1328.3 357.9 584.6 966.5 658.7 516.7 640.7 561.1 474.5 805.5 916.1 614.8 793.4 711.4 281.5 841.5 766.9 531.5 600.2 998.7 343.1 331.3 498.6 212.1 382.2 277.0 251.3 237.3 250.1 304.6 212.9 205.8 212.9 244.6 262.4 422.3 162.3 295.9 767.1 177.4 178.0 182.9 197.9 165.0 195.9 190.0 226.5 196.9 186.5 193.0 191.1 306.7 323.7 284.4 48.6 273.6 633.2 372.0 213.4 285.1 128.1 236.0 196.0 382.6 198.8 243.4 147.1 123.0 321.8 289.0 422.3 244.6 325.2 163.7 213.4 247.1 302.9 247.8 169.1 48.1 368.1 373.7 250.1 263.5 269.3 199.5 271.3 209.9 209.0 272.2 164.9 53.8 279.7 191.2 240.1 417.9 152.0 208.8 312.7 250.8 54.4 279.7 197.3 224.6 36.7 53.3 582.5 260.6 240.7 262.0 307.1 205.6 329.5 225.3 142.8 131.5 328.1 363.1 203.6 197.6 320.3 630.1 1056.1 267.7 281.2 289.0 518.3 EIF4G3 eIF4GII ENSG00000075151 "Eukaryotic translation initiation factor 4 gamma 3" O43432 1 20806292-21176888 "Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis, Translation regulation" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 515.2;Inhibitory neurons: 464.4;Microglial cells: 255.8;Oligodendrocyte precursor cells: 425.8;Oligodendrocytes: 483.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025031, HPA025039, HPA025041" Enhanced Approved Cytosol NA NA 68000 "Cluster 49: Eosinophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 32: U-937 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA025031: AB_1848102, HPA025039: AB_1848103, HPA025041: AB_1848104" "unprognostic (1.29e-1)" "unprognostic (8.38e-2)" "unprognostic (4.86e-2)" "unprognostic (1.54e-1)" "unprognostic (1.00e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (9.60e-7)" "unprognostic (1.02e-1)" "unprognostic (6.95e-3)" "unprognostic (8.36e-2)" "unprognostic (4.23e-2)" "unprognostic (1.22e-1)" "unprognostic (1.78e-2)" "unprognostic (9.37e-2)" "unprognostic (3.21e-2)" "unprognostic (5.07e-2)" "unprognostic (1.14e-1)" 21.3 20.7 5.2 20.5 6.2 32.3 17.9 1.6 19.7 18.5 57.9 22.7 15.0 21.1 17.1 19.8 18.8 19.9 18.3 4.8 12.7 16.1 14.9 16.4 17.4 5.0 1.5 17.2 12.1 39.5 26.5 15.6 4.9 17.4 24.4 26.4 12.6 20.6 42.2 18.5 17.4 27.5 0.0 17.1 17.3 74.3 3.7 17.1 35.7 23.4 19.9 22.6 16.7 16.6 31.8 25.2 78.3 32.0 80.1 77.9 16.4 66.8 70.4 46.5 46.1 27.2 33.4 60.7 41.1 73.2 42.6 34.5 48.4 53.9 64.3 50.4 48.2 31.6 47.7 18.9 38.5 53.1 56.5 86.4 39.9 47.8 61.2 69.0 59.2 22.3 23.9 42.0 66.3 25.1 16.6 19.2 23.3 36.7 21.3 31.7 29.8 21.4 40.8 16.4 46.1 35.4 70.0 29.6 35.9 46.3 20.7 58.0 60.7 51.4 19.1 73.5 30.2 18.8 22.5 0.3 63.5 78.7 48.4 0.5 0.5 0.9 0.7 0.0 0.3 0.6 0.3 0.3 1.0 0.8 0.2 0.3 1.2 0.4 0.3 0.6 0.5 0.5 5.2 6.2 1.6 19.7 4.8 12.7 5.0 1.5 4.9 0.0 3.7 16.6 50.9 19.2 30.5 181.5 29.5 20.6 19.9 15.0 17.1 52.0 19.2 17.4 44.5 14.3 28.2 16.5 66.7 4.6 51.1 51.3 0.0 20.6 173.9 66.6 81.2 42.7 16.3 26.1 515.2 19.4 8.8 33.8 46.4 46.8 26.6 44.9 46.1 14.7 23.1 50.5 464.4 21.6 4.1 31.5 11.3 121.8 44.7 39.3 14.2 255.8 18.0 18.6 28.8 425.8 483.4 24.8 32.1 44.8 27.3 21.0 15.7 10.3 51.1 40.5 32.9 36.6 31.3 100.6 51.2 33.8 26.3 3.4 23.7 68.4 29.6 28.0 EIF5 ENSG00000100664 "Eukaryotic translation initiation factor 5" P55010 14 103333544-103345025 "Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/84: 787.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA000867, CAB004226" Supported Enhanced Cytosol NA NA 77000 "Cluster 6: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 16: U-266 - Nucleosome" "Cluster 7: Non-specific - Mitochondria" Cytosol "CAB004226: AB_627507, HPA000867: AB_1078731" "unprognostic (1.39e-1)" "unprognostic (3.13e-1)" "unprognostic (4.02e-2)" "unprognostic (6.47e-3)" "unprognostic (6.33e-2)" "unprognostic (3.02e-1)" "unprognostic (2.01e-1)" "unprognostic (5.59e-2)" "unprognostic (7.82e-2)" "unprognostic (3.92e-3)" "unprognostic (1.08e-1)" "unprognostic (2.70e-2)" "prognostic favorable (5.67e-7)" "unprognostic (2.76e-1)" "unprognostic (8.41e-2)" "unprognostic (5.43e-3)" "unprognostic (3.14e-2)" 90.5 60.4 82.6 54.5 86.9 194.4 72.1 89.7 90.9 48.7 73.7 81.6 79.5 56.3 54.9 74.4 66.2 63.3 85.2 87.8 92.7 92.4 151.4 64.6 62.3 88.1 93.0 45.6 78.1 81.7 40.8 66.3 93.4 54.9 77.9 50.4 63.5 75.1 163.6 56.8 67.4 71.0 96.3 55.3 65.3 94.9 87.4 61.6 93.4 144.5 80.1 62.9 46.0 103.2 132.9 149.4 174.0 79.1 147.0 129.1 182.3 190.7 205.1 192.5 145.3 223.7 137.3 136.4 117.2 172.4 165.0 173.3 220.9 193.3 325.6 111.9 87.4 121.9 76.3 119.6 152.8 222.1 100.6 139.7 127.0 170.8 230.6 160.2 196.9 98.9 255.8 126.7 161.3 188.7 152.7 73.4 90.5 251.7 285.8 127.4 226.1 85.1 112.8 423.7 153.7 107.7 191.6 141.3 155.9 161.0 135.5 100.8 149.7 152.8 103.3 196.3 201.5 376.2 787.9 287.4 150.5 154.3 182.4 356.8 245.1 323.9 235.1 249.1 265.2 335.0 239.4 224.3 241.5 334.1 283.0 236.8 266.1 315.1 273.0 329.2 221.1 401.0 82.6 86.9 89.7 90.9 87.8 92.7 88.1 93.0 93.4 96.3 87.4 103.2 282.4 144.2 158.6 56.5 269.5 340.1 346.0 216.0 362.0 196.8 260.5 252.3 307.3 101.5 172.4 73.5 185.6 233.0 298.1 221.9 215.2 243.8 280.6 182.0 162.9 227.9 199.6 408.1 47.3 282.3 212.1 267.6 137.1 252.4 278.7 218.7 134.6 255.5 173.1 176.7 40.9 220.3 187.2 158.4 313.2 683.5 128.0 282.5 152.9 30.9 238.7 167.7 129.8 24.6 60.6 247.8 161.7 173.8 414.4 260.4 233.7 272.3 179.8 212.9 118.3 460.0 372.7 507.8 367.8 323.2 265.2 493.8 281.7 213.1 232.0 254.0 ELMO2 "CED-12, CED12, ELMO-2, FLJ11656, KIAA1834" ENSG00000062598 "Engulfment and cell motility 2" Q96JJ3 20 46366050-46432985 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Phagocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018811 Approved Supported Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA018811: AB_1848126" "unprognostic (1.19e-2)" "unprognostic (4.24e-2)" "unprognostic (2.07e-1)" "prognostic unfavorable (6.54e-4)" "unprognostic (3.71e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (4.08e-5)" "unprognostic (8.81e-2)" "unprognostic (3.06e-2)" "unprognostic (1.92e-1)" "prognostic favorable (6.10e-4)" "unprognostic (4.53e-1)" "unprognostic (4.42e-2)" "unprognostic (1.85e-1)" "unprognostic (1.91e-1)" "unprognostic (3.99e-2)" "unprognostic (1.20e-2)" 20.4 25.6 47.9 15.9 50.1 41.0 20.0 50.7 52.7 29.1 39.7 22.3 9.9 24.1 20.7 32.4 21.3 11.6 24.5 59.1 46.1 22.9 18.5 25.3 21.2 48.1 48.4 17.6 28.1 27.6 26.2 16.6 46.5 29.1 11.2 25.7 20.7 26.7 35.2 25.0 20.1 24.1 48.6 35.2 18.9 31.3 51.4 15.8 20.4 23.2 21.2 23.5 29.4 53.5 10.0 29.0 33.7 27.9 57.8 37.0 17.3 22.7 31.1 31.2 30.2 39.5 11.0 12.4 35.5 38.2 52.6 23.2 29.0 33.9 24.1 20.5 12.9 20.2 18.7 29.2 43.5 11.3 41.1 36.5 29.7 33.2 23.4 21.4 25.5 29.8 20.4 40.0 29.4 26.3 22.4 29.1 13.0 18.8 28.1 18.8 32.8 25.0 30.7 22.9 20.3 18.3 32.8 28.7 44.2 31.8 22.2 44.6 29.9 64.0 36.0 26.5 15.0 16.0 25.8 12.6 26.5 17.8 19.9 121.8 25.0 42.1 42.0 47.9 51.7 9.9 37.8 40.6 23.6 13.4 23.9 27.2 26.9 58.2 73.3 32.7 27.2 43.9 47.9 50.1 50.7 52.7 59.1 46.1 48.1 48.4 46.5 48.6 51.4 53.5 5.7 3.2 12.5 33.3 5.3 4.8 5.0 2.3 5.2 9.7 7.3 4.8 10.9 8.6 3.6 1.8 29.2 6.0 14.6 2.3 0.0 4.3 6.3 3.9 6.8 6.4 8.3 4.8 15.2 3.3 5.2 7.3 6.1 6.0 8.8 5.3 5.0 2.9 13.7 11.8 13.9 2.9 16.2 8.2 5.3 5.6 11.1 6.1 7.2 15.0 8.0 15.2 18.6 14.1 31.0 4.7 3.4 12.8 6.4 8.7 2.9 4.7 1.7 8.5 26.3 4.7 12.6 11.0 14.5 5.2 6.7 4.1 11.8 6.3 2.7 3.9 ELOF1 "ELF1, MGC4549" ENSG00000130165 "Elongation factor 1 homolog" P60002 19 11551147-11559236 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 497.5;Late spermatids: 1414.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045606 Uncertain Approved Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA045606: AB_10965133" "unprognostic (4.32e-2)" "prognostic favorable (1.83e-4)" "unprognostic (4.38e-3)" "unprognostic (3.39e-1)" "unprognostic (1.26e-1)" "unprognostic (3.29e-1)" "unprognostic (2.22e-2)" "unprognostic (2.65e-2)" "unprognostic (5.35e-2)" "unprognostic (4.90e-3)" "unprognostic (4.62e-2)" "unprognostic (1.26e-1)" "unprognostic (5.85e-2)" "unprognostic (2.93e-3)" "unprognostic (1.76e-2)" "unprognostic (7.09e-2)" "unprognostic (1.12e-2)" 42.7 65.7 78.3 33.3 81.2 62.2 40.8 91.9 95.2 63.1 82.6 57.4 31.3 68.9 43.4 51.4 60.2 29.4 54.4 81.2 89.1 54.9 80.3 40.9 45.3 76.3 77.9 60.3 79.7 48.6 74.4 25.5 83.9 64.1 25.0 22.2 56.4 45.1 57.9 48.1 48.9 34.8 75.5 56.0 66.4 205.2 81.0 47.1 47.4 47.8 38.6 53.2 47.7 101.5 138.7 94.7 63.7 88.0 78.0 78.5 32.8 87.2 73.0 117.1 117.6 94.4 37.1 88.1 83.5 79.3 76.3 63.5 78.2 121.2 81.2 70.2 79.6 110.8 61.8 90.5 87.6 72.5 72.9 76.8 88.7 103.6 74.8 83.7 57.9 82.8 156.1 111.8 71.0 177.8 108.2 84.1 166.1 69.9 172.3 79.2 54.5 93.2 97.6 63.2 80.2 101.4 70.3 83.6 85.2 58.1 70.2 57.5 40.6 120.3 45.5 127.6 133.0 129.0 188.5 75.1 112.1 101.0 61.5 99.6 130.4 144.2 99.5 128.8 92.5 195.5 104.0 93.5 115.0 160.4 92.8 83.4 87.1 106.1 147.3 189.4 153.0 146.4 78.3 81.2 91.9 95.2 81.2 89.1 76.3 77.9 83.9 75.5 81.0 101.5 15.4 16.0 23.9 7.8 50.5 84.9 53.4 74.7 43.9 24.7 47.9 39.2 31.9 50.1 37.7 33.1 8.4 83.6 52.3 59.9 105.7 80.1 497.5 38.9 30.3 32.4 60.3 67.8 10.0 103.0 80.8 42.2 19.4 20.2 22.2 29.5 44.3 37.0 76.7 15.2 10.3 47.1 59.0 53.0 68.9 1414.3 74.0 39.7 69.4 6.5 87.4 45.7 80.3 3.0 9.0 96.1 68.7 71.5 36.5 49.5 80.9 90.7 51.0 17.6 26.3 31.8 38.3 206.3 80.4 32.2 81.3 72.7 47.5 33.7 46.6 43.5 ELP3 "FLJ10422, KAT9" ENSG00000134014 "Elongator acetyltransferase complex subunit 3" Q9H9T3 8 28089673-28191156 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation, tRNA processing" "Acyltransferase, RNA-binding, Transferase, tRNA-binding" "Amyotrophic lateral sclerosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 74.3;Glandular and luminal cells: 125.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025297, HPA025812" Uncertain Enhanced Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Cytosol "HPA025297: , HPA025812: AB_10601369" "unprognostic (1.29e-2)" "unprognostic (1.26e-2)" "prognostic favorable (9.25e-4)" "unprognostic (3.49e-3)" "unprognostic (5.73e-2)" "unprognostic (1.10e-1)" "unprognostic (6.95e-2)" "unprognostic (2.07e-2)" "unprognostic (7.66e-2)" "unprognostic (1.22e-2)" "unprognostic (3.89e-1)" "unprognostic (3.46e-2)" "prognostic favorable (1.31e-5)" "unprognostic (2.29e-1)" "unprognostic (1.94e-1)" "unprognostic (1.39e-1)" "unprognostic (1.71e-1)" 13.6 13.0 17.3 11.0 19.0 6.6 16.6 19.0 20.3 26.1 14.1 13.8 9.7 22.6 11.3 12.2 16.1 15.4 16.3 19.2 19.8 17.5 21.0 12.1 16.3 18.2 17.4 16.1 10.9 16.8 11.6 12.0 18.5 13.4 15.6 12.4 9.8 19.2 27.9 12.0 11.1 14.9 18.0 13.7 10.7 14.2 20.1 14.6 18.3 26.5 19.5 13.6 10.6 19.6 34.5 36.3 26.1 21.7 28.9 27.8 17.6 17.7 26.6 31.9 31.2 23.9 14.7 60.0 24.6 27.7 31.3 21.5 26.3 34.3 41.2 11.2 12.4 38.0 21.9 41.3 27.7 21.4 27.5 32.7 48.4 24.4 36.5 26.2 32.4 41.3 46.2 34.8 32.9 20.9 47.3 30.1 28.9 29.5 12.0 34.4 24.4 24.2 33.8 25.5 13.6 25.5 18.1 14.4 28.4 21.3 29.2 24.2 25.7 23.6 35.2 26.8 26.5 14.4 25.9 45.2 26.7 24.7 26.8 20.2 16.1 12.9 25.0 22.2 28.7 17.9 21.8 26.0 18.3 21.2 18.7 22.1 3.8 25.0 27.0 17.3 23.5 19.1 17.3 19.0 19.0 20.3 19.2 19.8 18.2 17.4 18.5 18.0 20.1 19.6 8.8 3.2 12.7 26.4 14.4 2.7 7.1 10.2 10.8 8.5 6.8 8.9 16.6 7.2 11.1 7.3 22.9 15.1 12.5 6.3 7.9 12.5 7.4 74.3 25.0 10.1 1.2 9.4 32.2 9.9 14.8 9.5 9.7 125.2 8.2 12.8 10.4 19.0 14.9 15.2 38.7 7.0 0.0 13.2 4.0 4.8 8.4 9.6 1.8 31.9 9.6 8.7 24.7 49.3 45.9 9.3 11.3 10.1 11.0 7.6 9.9 13.1 10.6 12.2 0.0 9.5 8.4 20.2 17.7 6.9 2.4 10.4 13.7 15.6 10.5 5.4 EPHX2 ABHD20 ENSG00000120915 "Epoxide hydrolase 2" P34913 8 27490781-27545564 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Aromatic hydrocarbons catabolism, Detoxification, Lipid metabolism" "Hydrolase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 333.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 180.0;Hepatocytes: 131.5;Proximal enterocytes: 399.0;Proximal tubular cells: 259.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory CD4 T-cell: 35.0;naive CD4 T-cell: 106.7;naive CD8 T-cell: 50.4;T-reg: 29.6" "Lineage enriched" "Detected in many" 23 "T-cells: 106.7" "Cell line enhanced" "Detected in many" "JURKAT: 139.4;K-562: 51.6;OE19: 102.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023094, HPA023660" Enhanced Enhanced Cytosol NA NA 1100000 "Cluster 32: T-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA023094: AB_1848214, HPA023660: AB_1848215" "unprognostic (1.30e-1)" "prognostic favorable (2.45e-4)" "unprognostic (2.99e-2)" "unprognostic (3.62e-2)" "unprognostic (1.76e-2)" "unprognostic (3.30e-3)" "unprognostic (1.26e-3)" "unprognostic (3.31e-3)" "unprognostic (1.46e-1)" "unprognostic (3.55e-2)" "unprognostic (4.14e-3)" "unprognostic (1.98e-1)" "prognostic favorable (1.98e-10)" "unprognostic (9.82e-2)" "unprognostic (1.73e-1)" "unprognostic (8.12e-2)" "unprognostic (2.26e-1)" 19.3 74.0 14.5 9.1 15.0 1.9 30.1 14.4 14.1 21.0 42.2 61.4 112.8 17.7 27.2 38.6 41.6 9.4 29.1 13.2 15.3 166.3 333.2 11.2 17.2 16.1 17.3 38.0 64.5 54.8 35.8 8.5 15.9 64.6 57.6 21.5 36.5 27.2 16.2 43.4 128.4 15.4 15.8 10.8 23.4 9.0 15.8 65.9 22.6 13.8 20.8 19.7 23.4 15.7 15.3 10.1 6.3 8.1 0.4 0.0 4.8 1.3 0.9 0.7 0.2 8.0 10.1 0.1 5.9 4.1 3.2 10.7 1.1 2.6 0.5 0.0 4.7 22.5 1.1 24.8 3.4 0.1 4.5 8.6 10.7 0.1 1.1 2.5 0.5 139.4 51.6 0.2 0.0 4.7 14.9 0.5 10.1 102.4 17.2 0.1 0.1 0.4 8.7 2.2 5.1 16.0 12.1 14.2 15.0 4.6 21.8 4.2 0.2 0.0 3.8 1.8 0.1 12.5 10.1 0.2 0.4 0.1 0.1 0.1 0.1 0.0 7.8 0.0 11.3 4.5 35.0 12.7 0.1 2.5 106.7 50.4 0.2 4.6 0.1 0.2 29.6 20.0 14.5 15.0 14.4 14.1 13.2 15.3 16.1 17.3 15.9 15.8 15.8 15.7 6.3 6.4 17.0 16.3 6.1 11.9 18.6 10.1 29.6 34.1 17.2 18.4 23.7 20.0 9.7 27.6 79.2 22.8 1.0 82.7 180.0 8.8 7.5 6.9 4.8 9.4 23.4 3.8 3.0 6.4 2.5 12.1 15.8 1.5 5.7 17.4 17.5 131.5 2.2 33.7 7.2 63.4 2.0 4.6 1.2 4.8 29.8 3.6 5.4 2.8 2.6 91.5 3.1 7.5 5.1 3.1 83.7 18.8 4.5 20.5 399.0 259.3 24.1 52.4 0.0 11.5 10.2 1.3 13.9 39.2 18.3 8.2 11.9 78.5 101.3 10.8 EPRS1 "EARS, EPRS, GLUPRORS, PARS, QARS, QPRS" ENSG00000136628 "Glutamyl-prolyl-tRNA synthetase 1" P07814 1 219968600-220046530 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis, Translation regulation" "Aminoacyl-tRNA synthetase, Ligase, Multifunctional enzyme, RNA-binding" "Disease variant, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 22.3;Cardiomyocytes: 84.7;Cytotrophoblasts: 40.8;Extravillous trophoblasts: 59.3;Hofbauer cells: 42.6;Syncytiotrophoblasts: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026490, HPA030052" Enhanced Enhanced Cytosol NA NA 360000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA026490: AB_1855979, HPA030052: AB_10601466" "prognostic unfavorable (7.25e-4)" "unprognostic (1.19e-2)" "unprognostic (3.94e-2)" "unprognostic (2.60e-2)" "unprognostic (7.98e-3)" "unprognostic (1.12e-2)" "unprognostic (3.41e-3)" "unprognostic (1.32e-1)" "unprognostic (1.76e-1)" "unprognostic (1.30e-1)" "unprognostic (7.13e-2)" "unprognostic (5.12e-2)" "unprognostic (2.32e-2)" "unprognostic (2.18e-1)" "unprognostic (1.38e-1)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.62e-4)" 28.8 24.7 18.1 34.4 19.6 26.6 35.7 22.8 24.8 30.5 17.6 36.1 27.7 25.6 25.2 30.6 26.2 20.6 31.8 17.7 21.8 31.6 27.9 24.3 36.5 21.6 20.5 34.7 49.0 54.5 22.5 23.8 22.9 23.6 39.0 43.8 83.4 26.4 52.2 28.9 29.7 32.5 22.4 27.4 35.9 20.5 21.7 34.8 43.0 55.9 42.5 30.4 18.6 27.8 125.9 78.4 55.7 152.3 114.9 126.7 138.0 160.1 111.7 102.1 113.4 93.3 98.1 239.3 86.7 170.4 41.3 130.3 140.9 129.4 136.2 117.9 88.9 130.2 97.6 80.2 125.1 217.6 106.7 92.1 161.7 130.3 161.6 84.8 113.4 113.2 228.0 182.9 100.8 61.8 94.7 53.1 107.4 146.8 159.6 98.5 98.0 236.2 92.8 54.4 128.6 101.3 93.7 152.6 166.5 78.9 141.2 235.1 101.1 48.3 88.1 149.6 151.1 122.8 150.1 197.1 111.4 153.9 156.4 8.8 17.8 10.0 19.7 24.6 27.8 21.0 19.7 22.1 23.2 18.5 22.0 22.9 0.6 22.5 22.1 7.6 20.8 17.2 18.1 19.6 22.8 24.8 17.7 21.8 21.6 20.5 22.9 22.4 21.7 27.8 22.3 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 84.7 0.0 0.0 0.0 0.0 40.8 14.1 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 59.3 17.1 0.0 0.0 0.0 0.0 0.0 0.0 42.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.3 0.0 0.0 0.0 0.0 36.5 2.6 0.0 0.0 0.0 EPS8L1 "DRC3, FLJ20258, MGC23164, MGC4642" ENSG00000131037 "EPS8 like 1" Q8TE68 19 55072020-55087923 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 124.3;skin 1: 59.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 104.1;Gastric mucus-secreting cells: 108.1;Paneth cells: 110.2;Syncytiotrophoblasts: 428.0;Urothelial cells: 189.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 2.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 17.6;BEWO: 58.8;SK-BR-3: 19.6;T-47d: 28.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041851, HPA043545" Uncertain Supported Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA041851: AB_2677706, HPA043545: AB_2678544" "unprognostic (1.91e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (4.44e-4)" "unprognostic (7.18e-2)" "unprognostic (9.33e-2)" "unprognostic (2.54e-2)" "unprognostic (4.61e-2)" "unprognostic (1.43e-1)" "unprognostic (1.62e-1)" "unprognostic (9.43e-2)" "unprognostic (5.84e-3)" "unprognostic (2.65e-2)" "unprognostic (3.85e-3)" "unprognostic (5.04e-3)" "unprognostic (3.02e-1)" "unprognostic (5.41e-3)" "unprognostic (2.63e-1)" 4.5 0.2 0.0 0.9 0.1 0.1 4.0 0.0 0.1 24.0 0.0 3.5 2.3 1.5 0.0 124.3 14.8 0.9 0.6 0.1 0.0 25.1 0.7 3.9 0.0 0.1 0.1 0.5 5.6 2.1 2.1 5.4 0.1 9.2 0.6 0.0 20.4 2.5 0.5 59.7 2.0 0.0 0.0 0.6 27.0 0.6 0.2 0.1 17.4 0.0 1.6 2.7 37.1 0.2 17.6 0.7 0.6 0.4 0.0 0.0 58.8 1.5 0.1 0.0 0.1 7.6 13.7 0.3 3.4 0.0 0.1 9.7 0.4 2.1 0.0 0.3 1.6 1.3 0.6 0.5 0.2 2.6 10.8 0.0 3.6 0.0 0.0 0.0 0.0 1.2 6.2 0.1 0.0 8.0 0.9 2.6 0.8 12.7 0.0 0.1 0.0 5.4 2.7 3.6 0.2 3.8 1.0 19.6 0.8 0.6 28.9 3.2 1.3 0.0 0.7 0.0 0.0 2.4 3.1 1.6 3.3 0.9 2.0 1.1 0.2 2.3 0.3 0.0 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 1.4 0.3 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.2 4.0 9.6 6.1 0.3 0.8 2.0 28.4 39.5 8.6 0.0 16.3 15.1 2.6 8.6 92.2 31.3 0.0 55.1 4.0 104.1 13.7 20.4 1.6 29.1 6.3 10.7 3.0 0.0 0.1 10.2 26.8 4.7 108.1 41.7 10.2 5.4 10.0 0.1 8.9 0.0 0.1 39.0 24.4 1.9 3.4 4.5 1.2 2.6 21.4 0.0 5.2 0.2 6.2 0.0 0.1 94.5 110.2 0.7 1.0 48.7 12.7 1.1 53.6 0.6 26.3 0.5 21.6 1.6 3.6 6.6 4.0 428.0 2.8 0.3 22.1 189.4 EPS8L2 "FLJ21935, FLJ22171, MGC3088" ENSG00000177106 "EPS8 like 2" Q9H6S3 11 694438-727727 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 188.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 211.4;Paneth cells: 175.3;Proximal enterocytes: 235.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 3.1" "Lineage enriched" "Detected in single" 8 "dendritic cells: 3.1" "Cell line enhanced" "Detected in many" "A-431: 234.3;BEWO: 220.8;CAPAN-2: 206.6;SK-BR-3: 257.5" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 10 "cerebellum: 9.2" HPA041143 Approved Supported Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA041143: AB_10794985" "unprognostic (1.39e-2)" "unprognostic (1.07e-1)" "unprognostic (7.58e-2)" "unprognostic (3.40e-2)" "prognostic unfavorable (2.31e-4)" "unprognostic (6.87e-2)" "unprognostic (3.27e-2)" "unprognostic (1.33e-1)" "unprognostic (4.82e-2)" "unprognostic (4.26e-2)" "unprognostic (2.54e-1)" "unprognostic (1.92e-1)" "unprognostic (3.25e-2)" "unprognostic (2.51e-2)" "unprognostic (4.19e-1)" "unprognostic (2.79e-1)" "unprognostic (5.03e-2)" 7.8 11.2 5.2 5.7 4.8 0.0 27.0 8.9 5.5 49.4 4.9 42.7 100.8 11.4 3.5 188.5 19.2 13.3 4.3 4.5 6.8 98.4 101.7 32.4 0.7 10.9 9.2 11.8 43.7 3.8 11.5 17.7 6.2 29.3 15.5 1.0 94.6 15.2 1.3 76.3 105.0 2.9 7.1 1.4 48.1 3.2 7.1 2.0 70.2 0.4 10.9 17.5 80.1 6.5 234.3 68.6 0.2 1.6 2.7 14.4 220.8 20.1 20.3 29.2 12.5 51.4 206.6 0.4 81.6 21.4 5.4 122.4 0.6 117.8 6.4 0.6 5.4 0.0 27.7 94.7 16.3 0.3 0.4 8.1 77.8 8.0 18.7 12.3 0.2 0.1 1.8 1.1 3.2 72.1 0.5 1.3 2.7 71.5 24.0 0.5 0.8 1.8 103.8 55.2 0.8 0.8 75.9 257.5 0.5 14.3 94.9 0.2 1.5 11.2 27.3 7.2 1.6 0.9 1.0 0.8 6.1 0.6 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 3.1 0.0 0.1 5.2 4.8 8.9 5.5 4.5 6.8 10.9 9.2 6.2 7.1 7.1 6.5 1.8 141.1 51.8 3.9 11.2 19.8 26.2 48.8 51.8 0.6 39.1 37.0 4.5 57.2 62.4 90.1 0.0 47.9 21.6 211.4 27.4 55.2 1.0 47.3 7.1 4.7 43.8 1.3 3.1 80.0 33.4 11.5 131.0 60.8 7.0 0.4 0.7 59.4 4.7 0.0 3.8 76.8 32.6 2.1 7.8 2.3 18.0 2.7 14.2 2.8 3.1 10.0 16.5 2.0 0.7 83.2 175.3 11.7 7.6 33.6 235.9 108.2 60.9 1.5 0.0 0.9 7.5 1.1 4.8 74.9 24.4 92.5 18.6 0.9 77.2 32.1 ERMARD "C6orf70, dJ266L20.3, FLJ11152" ENSG00000130023 "ER membrane associated RNA degradation" Q5T6L9 6 169751622-169781600 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 49.9;Late spermatids: 48.5;Spermatocytes: 37.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041741 Approved Approved Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA041741: AB_10804116" "unprognostic (2.66e-3)" "unprognostic (2.75e-1)" "unprognostic (2.33e-1)" "unprognostic (2.28e-2)" "unprognostic (1.18e-1)" "unprognostic (3.18e-1)" "unprognostic (2.24e-2)" "unprognostic (7.41e-3)" "unprognostic (1.96e-1)" "unprognostic (8.14e-2)" "unprognostic (1.66e-3)" "unprognostic (4.74e-2)" "unprognostic (3.06e-2)" "unprognostic (3.08e-1)" "unprognostic (1.88e-1)" "unprognostic (2.71e-1)" "unprognostic (1.31e-2)" 13.8 14.6 5.3 8.4 7.1 10.1 13.1 5.4 6.7 13.7 5.6 11.2 6.3 13.8 20.5 10.5 13.2 7.7 6.8 5.3 5.9 16.1 18.6 9.7 13.8 6.9 6.1 17.4 11.4 6.9 15.4 7.4 7.2 12.7 7.4 14.6 11.0 8.6 14.9 18.7 13.6 6.4 6.5 17.3 10.9 22.1 6.1 9.9 13.2 2.5 13.6 11.2 10.8 9.1 5.1 7.5 9.7 14.8 6.9 11.4 5.1 5.3 7.7 5.0 6.3 2.0 8.3 8.0 4.8 6.5 6.1 13.3 4.0 10.3 4.4 8.6 4.4 11.5 9.9 3.0 13.7 16.1 7.6 13.4 10.4 6.1 15.5 12.8 3.4 14.0 8.0 11.4 6.5 7.7 6.8 14.4 3.2 5.7 5.4 7.5 6.0 13.0 6.2 4.0 3.8 7.0 9.0 9.0 4.9 6.3 7.1 12.8 5.3 5.7 3.4 9.1 6.5 13.1 17.5 6.7 7.2 9.7 6.6 1.6 4.2 1.8 5.2 7.9 5.2 5.1 6.0 5.9 4.4 6.0 4.7 4.4 0.4 5.2 9.7 3.7 7.6 3.9 5.3 7.1 5.4 6.7 5.3 5.9 6.9 6.1 7.2 6.5 6.1 9.1 8.5 3.2 11.1 20.2 6.2 4.1 4.4 7.7 5.2 12.0 5.9 5.1 2.8 5.7 7.7 5.5 10.4 12.2 4.7 3.0 11.7 9.8 49.9 10.8 9.4 5.0 6.0 4.6 9.3 8.5 8.3 7.0 5.6 6.9 2.5 11.7 7.9 10.1 5.9 5.0 11.8 2.9 6.1 5.7 4.4 48.5 4.4 6.1 3.6 8.4 5.6 14.6 5.2 17.1 20.7 5.3 2.4 4.5 4.4 2.5 5.7 9.5 15.5 10.8 6.6 5.5 5.8 37.8 18.0 5.5 3.1 7.1 4.7 10.3 3.4 3.4 ERRFI1 "GENE-33, MIG-6, RALT" ENSG00000116285 "ERBB receptor feedback inhibitor 1" Q9UJM3 1 8004404-8026309 "Predicted intracellular proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 743.8;pancreas: 678.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1242.3;Basal prostatic cells: 1428.1;Hepatocytes: 722.3;Suprabasal keratinocytes: 732.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "non-classical monocyte: 2.0" "Lineage enriched" "Detected in single" 5 "monocytes: 2.0" "Cell line enhanced" "Detected in many" "HHSteC: 558.4;LHCN-M2: 442.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076543 Supported Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "HPA076543: " "unprognostic (2.13e-3)" "unprognostic (1.01e-2)" "unprognostic (2.34e-1)" "unprognostic (1.71e-2)" "unprognostic (2.50e-3)" "unprognostic (1.66e-3)" "unprognostic (2.27e-2)" "unprognostic (1.05e-2)" "unprognostic (1.26e-1)" "unprognostic (1.47e-1)" "unprognostic (4.50e-2)" "unprognostic (2.10e-1)" "unprognostic (1.19e-3)" "unprognostic (1.11e-3)" "unprognostic (1.18e-1)" "unprognostic (2.34e-1)" "unprognostic (8.03e-3)" 143.6 41.7 13.8 31.0 15.3 1.8 127.6 33.0 20.5 87.0 42.2 61.5 33.3 78.1 18.3 51.2 75.8 131.1 53.3 16.7 20.3 157.3 743.8 82.8 17.6 31.9 16.7 148.5 678.8 88.0 112.1 125.6 17.4 53.1 23.4 36.3 76.1 26.0 225.9 124.6 47.2 88.5 28.6 9.5 125.0 16.5 18.7 18.4 113.4 30.2 12.5 86.9 75.5 20.9 86.1 49.7 20.8 28.2 192.6 143.0 215.7 81.9 23.8 15.0 17.5 22.2 218.9 1.4 47.9 27.6 102.5 18.2 5.8 144.7 68.2 2.6 16.1 1.3 15.1 260.1 558.4 0.9 3.3 195.8 142.7 49.4 118.7 208.4 38.3 3.6 6.1 0.7 442.5 36.8 0.3 5.5 50.0 66.3 121.7 7.4 233.8 1.4 69.3 27.0 14.3 8.5 16.2 36.5 26.0 145.6 25.4 2.0 54.4 57.7 33.9 49.0 116.6 1.3 1.1 1.5 222.0 3.8 54.4 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.4 0.4 0.0 0.1 0.3 0.4 0.0 0.0 2.0 0.1 0.2 0.0 13.8 15.3 33.0 20.5 16.7 20.3 31.9 16.7 17.4 28.6 18.7 20.9 93.0 221.2 108.7 22.5 9.2 1242.3 1428.1 228.6 249.8 9.8 186.3 115.9 52.1 177.3 198.7 27.6 14.6 87.6 25.7 161.9 31.3 99.1 24.0 209.6 74.4 29.8 109.5 21.5 18.4 111.2 51.0 130.1 56.6 336.3 14.5 3.9 32.5 722.3 10.0 3.3 16.5 70.2 59.0 11.7 95.0 63.9 51.9 17.9 71.2 8.4 0.6 40.0 3.1 13.0 30.9 144.9 127.2 38.4 6.6 382.2 78.1 131.1 86.3 9.9 6.6 113.9 93.3 21.1 21.8 152.6 732.9 259.0 33.5 4.9 82.7 543.4 EVA1B "C1orf78, FAM176B, FLJ10647" ENSG00000142694 "Eva-1 homolog B" Q9NVM1 1 36322031-36324154 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 143.9;Extravillous trophoblasts: 250.3;Syncytiotrophoblasts: 161.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 23.3;BJ: 29.0;BJ hTERT+: 22.4;HSkMC: 20.4;NB-4: 41.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041928, HPA043537" Approved Approved Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA041928: AB_2677752, HPA043537: AB_2678538" "prognostic favorable (4.58e-4)" "unprognostic (5.66e-3)" "unprognostic (1.04e-3)" "unprognostic (3.20e-2)" "unprognostic (1.22e-2)" "unprognostic (4.00e-3)" "prognostic unfavorable (4.82e-4)" "unprognostic (1.45e-1)" "unprognostic (8.33e-2)" "unprognostic (1.48e-1)" "unprognostic (1.09e-1)" "unprognostic (2.60e-1)" "prognostic unfavorable (4.79e-5)" "unprognostic (1.87e-2)" "unprognostic (3.96e-2)" "unprognostic (1.39e-1)" "unprognostic (2.02e-1)" 26.8 19.4 5.5 3.4 5.4 2.0 35.8 5.5 6.4 41.8 7.5 19.8 2.5 34.0 0.6 12.2 21.9 1.3 19.9 5.0 5.9 39.2 8.5 26.1 1.9 6.8 6.4 30.2 7.8 1.9 9.4 9.0 6.0 29.0 0.4 0.0 28.7 2.9 5.7 24.0 15.8 1.6 7.0 37.6 14.2 7.5 6.6 0.5 33.9 1.0 0.5 22.0 30.1 5.7 0.7 2.7 1.6 3.0 7.9 23.3 6.8 29.0 22.4 5.4 6.3 0.2 2.1 0.0 8.5 9.2 1.0 0.2 0.2 1.1 1.1 3.3 6.0 3.6 0.6 1.3 17.4 0.1 0.6 20.4 0.0 6.9 0.3 0.9 8.7 0.1 1.4 1.0 3.6 0.2 0.1 41.7 1.7 0.0 10.4 1.5 0.3 7.1 4.6 0.0 0.1 3.9 2.8 1.1 13.3 1.1 0.0 2.7 12.7 7.9 0.0 10.5 2.7 0.3 0.0 0.1 2.9 1.8 7.1 4.0 0.9 0.0 0.2 0.3 0.6 0.0 0.3 0.5 0.5 0.0 0.0 0.0 1.7 1.6 0.1 0.0 1.2 0.1 5.5 5.4 5.5 6.4 5.0 5.9 6.8 6.4 6.0 7.0 6.6 5.7 82.8 0.0 0.0 2.3 6.2 16.2 19.3 7.3 0.0 0.0 143.9 90.6 2.2 1.5 5.1 7.3 0.0 54.7 8.4 0.3 1.9 20.2 7.1 9.4 88.4 53.9 0.0 0.8 0.0 15.2 250.3 56.6 0.0 15.2 4.5 15.7 84.9 0.9 48.7 0.0 0.0 0.1 6.1 41.3 28.8 24.8 50.7 30.4 12.4 5.6 10.2 14.1 4.1 0.0 0.1 28.9 1.1 48.5 7.9 56.6 0.4 7.7 5.6 0.9 26.3 7.8 98.4 8.4 3.3 0.7 12.4 161.3 9.7 58.2 0.5 30.3 EXOC8 "EXO84, Exo84p, SEC84" ENSG00000116903 "Exocyst complex component 8" Q8IYI6 1 231332753-231337852 "Human disease related genes, Predicted intracellular proteins, Transporters" "Exocytosis, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027438 Approved Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 2: Karpas-707 - Immune response" "Cluster 44: Endometrium - Transcription" Cytosol "HPA027438: AB_1848318" "unprognostic (3.85e-2)" "unprognostic (6.52e-2)" "unprognostic (1.11e-1)" "unprognostic (2.05e-2)" "unprognostic (4.83e-2)" "unprognostic (5.82e-2)" "unprognostic (4.85e-2)" "unprognostic (1.55e-1)" "unprognostic (2.34e-1)" "unprognostic (2.69e-1)" "unprognostic (2.09e-2)" "unprognostic (1.74e-1)" "unprognostic (8.39e-2)" "unprognostic (1.77e-1)" "unprognostic (3.79e-2)" "unprognostic (2.21e-2)" "unprognostic (1.04e-1)" 6.1 5.4 3.0 7.9 3.1 16.9 6.7 4.8 3.9 5.2 2.9 5.0 5.9 4.5 4.8 5.5 4.8 5.0 5.2 3.3 4.2 5.9 6.2 5.9 9.2 3.1 2.7 7.0 6.3 8.7 2.9 6.5 3.4 5.5 4.7 7.5 5.4 3.8 14.1 5.9 6.3 4.4 2.5 8.3 6.8 4.1 3.7 7.4 8.4 9.8 9.1 5.3 3.7 3.7 8.2 9.0 5.4 5.4 13.9 11.2 13.0 10.0 8.4 7.4 7.0 8.6 8.1 9.4 8.6 10.1 6.6 13.2 7.9 10.8 8.1 12.2 19.0 5.7 11.8 5.5 7.8 10.1 15.2 11.3 11.7 11.0 10.4 8.7 9.2 9.6 10.6 21.9 12.0 4.3 9.4 6.2 8.2 10.4 7.6 6.1 8.3 12.0 9.3 9.5 7.1 7.6 10.1 13.1 10.1 4.3 12.5 14.5 12.6 9.9 7.0 13.3 17.7 16.2 9.9 10.1 11.3 8.9 12.7 1.7 0.7 1.3 0.4 0.8 0.5 0.4 0.6 0.5 0.5 0.5 0.7 1.2 2.2 0.8 1.6 0.7 0.6 0.5 3.0 3.1 4.8 3.9 3.3 4.2 3.1 2.7 3.4 2.5 3.7 3.7 10.0 9.6 9.8 2.0 10.9 18.5 5.6 4.0 8.0 4.3 8.1 5.5 8.9 11.5 8.3 9.2 6.2 4.6 10.4 6.7 1.9 3.3 1.6 8.1 9.0 9.3 4.8 7.4 5.3 3.5 2.8 8.2 14.3 10.4 2.5 4.3 6.8 9.6 5.8 3.3 5.9 3.7 2.0 13.3 7.1 1.1 4.1 7.6 3.6 3.7 5.7 5.8 5.2 2.5 6.6 5.0 1.2 5.7 7.9 6.0 6.9 5.2 5.6 12.3 0.0 8.4 5.2 5.1 5.0 11.0 14.8 9.3 10.0 4.6 4.2 8.6 EYA2 EAB1 ENSG00000064655 "EYA transcriptional coactivator and phosphatase 2" O00167 20 46894624-47188844 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 55.6" "Cell type enhanced" "Detected in many" "Astrocytes: 153.8;Basal prostatic cells: 47.5;Basal respiratory cells: 50.4;Endometrial ciliated cells: 43.7;Glandular and luminal cells: 53.8;Oligodendrocyte precursor cells: 48.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 69.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBEC3-KT: 40.1;SCLC-21H: 58.3;U-266/70: 110.9;U-266/84: 139.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027024, HPA059291" Uncertain Supported Cytosol NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol "HPA027024: AB_1848334, HPA059291: AB_2683967" "unprognostic (1.08e-1)" "unprognostic (5.71e-3)" "unprognostic (4.03e-1)" "prognostic favorable (4.30e-5)" "unprognostic (3.32e-2)" "unprognostic (1.72e-1)" "unprognostic (4.94e-3)" "unprognostic (1.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.21e-1)" "unprognostic (2.54e-1)" "unprognostic (2.65e-1)" "unprognostic (7.06e-2)" "unprognostic (2.15e-1)" "unprognostic (2.78e-1)" "unprognostic (4.17e-3)" "unprognostic (1.56e-1)" 12.0 1.5 12.3 2.4 14.1 0.0 11.0 15.6 12.3 55.6 11.2 9.3 0.3 17.2 3.7 34.2 34.0 1.8 5.0 10.7 11.8 4.7 2.1 2.2 0.8 14.6 14.4 0.7 1.9 9.4 5.3 6.3 13.7 23.6 3.1 1.2 31.2 9.3 2.5 5.3 1.1 1.8 11.8 0.6 8.9 5.6 13.4 18.8 14.6 3.4 6.6 4.9 16.5 11.0 0.2 4.4 0.2 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.7 2.5 1.9 0.3 40.1 0.0 0.0 8.1 0.0 0.1 0.0 0.0 0.1 0.3 2.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.3 7.7 0.1 0.0 0.6 0.1 0.0 0.1 0.8 0.5 0.0 0.0 58.3 0.0 0.0 24.8 0.0 3.0 5.3 0.2 0.0 0.0 4.5 0.3 8.8 110.9 139.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 14.1 15.6 12.3 10.7 11.8 14.6 14.4 13.7 11.8 13.4 11.0 0.4 0.0 0.0 153.8 0.9 0.6 47.5 50.4 14.8 0.4 7.8 7.6 0.5 2.8 33.0 0.0 6.2 27.7 0.0 2.5 0.0 0.9 0.2 43.7 3.9 0.6 1.2 0.0 1.5 0.0 3.0 4.8 9.2 53.8 1.3 9.8 0.4 3.3 7.4 0.0 5.1 0.6 34.6 0.0 0.4 0.3 0.0 1.1 3.6 13.1 2.6 0.0 0.0 48.7 1.0 1.1 1.7 0.7 3.4 10.9 0.0 6.3 22.2 0.4 0.0 0.3 2.8 0.2 7.4 16.0 0.3 10.8 0.6 4.2 3.6 34.6 FAAH FAAH-1 ENSG00000117480 "Fatty acid amide hydrolase" O00519 1 46394317-46413848 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 128.5;Proximal enterocytes: 87.4;Spermatocytes: 89.0" "Cancer enhanced" "Detected in all" "prostate cancer: 68.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 29.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 37.5;OE19: 18.8;RT4: 42.4;SK-BR-3: 21.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007425 Approved Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA007425: AB_1078820" "unprognostic (6.12e-2)" "unprognostic (2.04e-1)" "unprognostic (2.51e-2)" "prognostic favorable (1.51e-4)" "unprognostic (1.72e-1)" "unprognostic (4.97e-2)" "unprognostic (2.00e-1)" "unprognostic (6.64e-3)" "unprognostic (2.91e-2)" "unprognostic (2.33e-1)" "unprognostic (4.39e-3)" "unprognostic (9.86e-2)" "prognostic favorable (4.25e-5)" "prognostic favorable (3.63e-5)" "unprognostic (2.66e-1)" "unprognostic (9.97e-2)" "unprognostic (5.00e-3)" 7.5 14.2 23.5 2.9 28.4 10.4 9.5 25.6 29.6 7.5 29.3 18.9 22.0 3.9 9.1 8.7 12.0 5.2 5.0 24.6 23.3 20.0 32.8 7.8 2.5 32.1 25.4 3.9 22.4 24.6 19.0 3.4 28.7 44.1 15.2 5.5 17.4 7.1 9.5 12.1 22.0 2.3 27.9 3.3 17.1 46.8 26.4 7.1 38.6 5.6 2.7 6.9 8.2 45.8 5.0 1.2 0.8 1.0 1.2 0.8 37.5 1.0 0.5 0.5 0.8 7.3 11.4 0.3 3.9 0.7 0.4 16.2 0.7 2.3 0.2 2.2 5.4 0.1 0.2 3.5 0.8 1.4 2.8 0.6 10.7 0.4 1.3 0.4 0.0 0.9 0.1 0.8 0.0 10.7 0.8 2.2 3.2 18.8 0.4 0.9 0.4 0.2 9.0 42.4 4.8 3.6 5.6 21.2 0.2 0.9 14.6 14.5 0.0 0.1 0.6 1.1 0.7 2.1 1.0 0.6 0.1 13.4 0.4 0.0 6.9 29.1 0.4 1.9 0.2 0.1 0.4 0.2 8.2 0.1 0.6 0.6 0.4 0.5 1.0 8.8 0.2 1.4 23.5 28.4 25.6 29.6 24.6 23.3 32.1 25.4 28.7 27.9 26.4 45.8 1.2 22.4 13.2 6.5 2.4 5.2 29.0 6.8 10.2 15.5 15.4 9.0 2.9 27.1 11.0 22.0 43.8 16.3 7.3 51.6 0.0 12.4 50.7 9.5 1.9 1.8 15.5 6.6 15.7 6.4 8.7 3.7 37.8 6.0 0.0 6.3 0.4 37.1 2.8 1.7 11.4 38.2 10.2 2.5 4.2 128.5 7.5 3.3 5.4 1.9 2.5 7.3 0.0 7.5 45.1 4.2 41.3 4.5 0.7 20.1 87.4 22.6 5.2 14.5 0.0 2.9 3.2 89.0 23.0 6.4 6.0 12.4 1.2 1.3 55.2 18.9 FAM102A "bA203J24.7, C9orf132, Eeig1, SYM-3A" ENSG00000167106 "Family with sequence similarity 102 member A" Q5T9C2 9 127940582-127980989 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 131.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036030 Approved Cytosol NA NA "Cluster 13: T-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 3: HMC-1 - Innate immune response" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "HPA036030: AB_10670675" "unprognostic (3.27e-1)" "unprognostic (1.66e-3)" "unprognostic (1.06e-3)" "unprognostic (4.69e-3)" "unprognostic (2.32e-1)" "unprognostic (1.21e-2)" "unprognostic (8.50e-2)" "unprognostic (2.97e-1)" "unprognostic (8.36e-2)" "unprognostic (1.01e-2)" "unprognostic (9.28e-2)" "unprognostic (1.76e-1)" "unprognostic (1.17e-1)" "unprognostic (1.69e-1)" "unprognostic (1.25e-1)" "unprognostic (8.28e-3)" "unprognostic (6.98e-2)" 11.4 40.6 63.9 35.4 86.8 13.9 19.7 64.4 77.2 52.5 20.3 38.9 55.6 33.5 19.4 61.1 47.5 46.7 14.1 59.0 58.0 37.4 39.0 16.1 59.3 76.5 79.4 20.6 35.1 22.4 51.2 9.0 70.7 23.7 17.5 14.5 44.0 20.1 4.0 45.2 65.7 27.2 60.4 27.3 105.5 32.6 91.2 40.1 23.3 3.9 44.7 37.1 47.0 144.1 26.5 56.7 11.9 9.6 25.1 30.0 45.1 10.1 27.4 6.6 4.1 33.1 46.0 29.8 6.6 19.4 14.2 28.4 6.3 5.1 2.5 14.4 6.3 8.9 14.5 30.1 15.6 4.4 66.3 12.2 26.0 18.9 8.0 13.3 9.2 18.0 7.4 36.7 7.7 68.6 17.8 9.5 14.8 52.0 27.4 9.2 8.8 10.7 19.1 44.3 18.7 9.2 16.7 36.9 23.9 12.8 69.3 5.7 9.8 10.3 11.1 55.1 15.5 49.1 72.7 20.7 44.7 5.9 24.9 0.7 0.1 2.5 1.9 0.0 6.1 4.8 9.7 5.7 0.1 1.1 8.9 6.3 0.1 0.4 0.1 0.0 13.4 3.9 63.9 86.8 64.4 77.2 59.0 58.0 76.5 79.4 70.7 60.4 91.2 144.1 3.3 6.4 9.0 37.5 37.2 21.9 29.4 11.5 24.5 15.6 44.9 26.9 11.4 41.5 14.9 64.4 10.4 6.3 10.7 91.2 7.9 61.5 7.0 51.0 35.8 8.6 28.1 8.0 13.8 100.5 5.9 12.4 99.4 46.0 18.4 22.3 54.7 49.1 3.3 26.9 12.2 42.1 40.7 6.9 8.8 7.4 34.2 3.8 23.2 5.6 4.4 69.0 1.0 26.2 103.5 59.3 51.9 43.2 22.6 69.9 131.9 12.9 33.2 14.3 0.0 6.0 7.4 9.8 10.2 38.6 47.9 5.3 40.3 13.1 28.7 122.4 FAM120A "C9orf10, KIAA0183, OSSA" ENSG00000048828 "Family with sequence similarity 120A" Q9NZB2 9 93451685-93566112 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019734, HPA055800" Approved Enhanced Cytosol NA NA 12000 "Cluster 35: T-regs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA019734: AB_1848369, HPA055800: AB_2682925" "unprognostic (5.92e-2)" "unprognostic (2.15e-1)" "unprognostic (1.45e-1)" "prognostic favorable (5.03e-4)" "unprognostic (3.36e-1)" "unprognostic (2.33e-2)" "unprognostic (8.93e-2)" "unprognostic (5.84e-2)" "unprognostic (3.06e-1)" "unprognostic (1.07e-1)" "unprognostic (1.27e-2)" "unprognostic (3.71e-3)" "prognostic favorable (1.08e-7)" "unprognostic (8.16e-2)" "unprognostic (1.60e-1)" "unprognostic (2.64e-1)" "unprognostic (1.00e-2)" 48.1 47.8 26.7 59.7 30.8 49.9 37.8 25.8 27.0 45.0 55.0 74.4 59.0 39.2 36.0 46.6 50.8 42.3 60.9 26.0 24.2 47.7 55.7 42.0 56.5 32.6 29.3 39.1 57.9 87.3 26.8 60.3 28.8 42.7 69.1 30.6 56.2 40.8 81.7 41.9 58.4 50.9 25.3 49.0 69.3 17.4 30.3 45.5 49.0 71.4 45.6 53.4 33.0 28.7 179.7 145.4 32.0 92.8 93.7 116.6 100.3 123.2 107.8 92.9 68.0 47.5 108.2 116.1 68.9 156.2 73.7 188.8 86.5 144.3 71.1 117.0 62.8 63.8 126.1 75.3 104.6 109.0 83.5 114.3 87.2 105.7 166.3 90.9 133.7 81.0 74.4 94.9 101.3 202.8 108.2 61.4 41.2 212.7 134.3 62.1 85.6 97.4 112.3 107.2 85.8 52.5 139.5 166.4 86.0 31.4 91.0 70.6 140.6 99.6 71.6 123.8 136.4 74.2 78.6 44.8 107.9 96.6 90.9 3.1 6.6 5.2 4.9 7.5 4.1 4.4 4.3 4.8 6.1 3.5 3.0 4.4 13.1 4.3 9.3 3.9 8.3 4.1 26.7 30.8 25.8 27.0 26.0 24.2 32.6 29.3 28.8 25.3 30.3 28.7 64.0 44.8 93.9 67.9 42.7 102.2 49.6 56.6 70.6 30.0 86.5 49.0 112.3 77.2 75.2 75.4 50.1 73.8 49.2 164.3 21.5 50.1 26.1 77.5 76.2 64.9 91.8 60.2 92.1 74.7 104.9 60.5 123.8 92.3 48.8 66.1 63.1 186.6 71.0 40.4 62.5 176.8 36.7 146.4 78.6 9.8 66.8 103.4 53.4 80.6 111.0 35.7 35.0 64.3 80.9 86.4 92.0 65.5 60.8 125.8 81.0 75.7 87.8 33.7 39.5 63.5 68.6 12.3 12.4 91.1 114.2 103.4 49.3 94.4 177.2 109.0 FAM151B UNQ9217 ENSG00000152380 "Family with sequence similarity 151 member B" Q6UXP7 5 80487969-80542563 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 17.8;Inhibitory neurons: 21.6;Oligodendrocyte precursor cells: 18.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043805 Uncertain Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA043805: AB_10794287" "unprognostic (1.29e-1)" "unprognostic (7.11e-2)" "unprognostic (1.67e-3)" "unprognostic (1.28e-4)" "unprognostic (1.90e-2)" "unprognostic (4.46e-4)" "unprognostic (2.63e-2)" "unprognostic (2.45e-1)" "unprognostic (2.10e-2)" "unprognostic (9.63e-2)" "unprognostic (1.20e-1)" "unprognostic (3.44e-2)" "unprognostic (6.86e-3)" "unprognostic (1.13e-1)" "unprognostic (2.66e-1)" "unprognostic (2.50e-2)" "unprognostic (1.63e-1)" 0.7 1.0 0.7 0.7 0.9 4.7 0.7 0.4 0.9 0.8 0.4 0.4 0.4 0.6 0.9 0.5 1.3 0.9 0.9 1.0 0.5 1.1 0.8 0.7 0.3 0.6 0.4 0.6 0.6 1.1 0.7 1.8 0.2 0.8 0.6 1.0 0.4 0.5 0.3 0.3 0.3 0.9 0.5 0.7 0.5 0.7 0.9 0.2 0.8 0.3 0.4 0.7 0.5 0.7 0.1 1.5 0.7 3.2 2.6 3.7 1.0 1.3 1.9 1.1 2.4 0.1 1.2 0.0 0.2 3.4 3.4 0.8 1.1 0.2 0.9 0.3 0.7 0.3 0.5 0.3 1.1 0.5 1.7 1.8 1.1 1.2 0.1 2.1 1.7 0.4 0.1 0.5 1.8 1.1 0.2 0.2 0.1 0.3 0.6 0.4 2.6 0.4 1.3 0.5 0.3 0.7 0.4 1.2 1.1 0.3 1.7 1.4 0.7 0.2 0.2 0.0 0.5 0.0 0.7 0.0 1.8 1.4 1.1 0.0 0.4 0.5 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.7 0.9 0.4 0.9 1.0 0.5 0.6 0.4 0.2 0.5 0.9 0.7 0.3 0.0 0.0 3.6 0.4 0.3 0.5 2.2 0.6 1.0 1.4 0.8 1.8 2.8 1.7 3.7 0.0 7.9 0.1 0.3 0.0 1.5 4.1 3.9 1.3 0.9 0.0 0.0 17.8 2.1 6.7 2.0 1.5 2.6 1.3 1.1 0.4 0.3 5.1 1.7 21.6 0.5 0.0 4.8 1.2 1.9 1.2 3.6 0.0 6.5 2.2 1.5 0.0 18.6 8.5 0.3 0.3 0.4 1.3 0.7 0.6 4.3 3.7 0.8 0.0 1.2 0.8 4.7 0.9 1.0 1.0 7.9 0.1 1.3 0.2 0.6 FAM160A1 FLJ43373 ENSG00000164142 "Family with sequence similarity 160 member A1" Q05DH4 4 151409176-151670503 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 32.3;skeletal muscle: 34.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 11.9;Excitatory neurons: 15.8;Oligodendrocyte precursor cells: 19.1;Suprabasal keratinocytes: 14.5" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 11 "cerebellum: 13.8" "Immune cell enriched" "Detected in single" 14 "plasmacytoid DC: 2.5" "Lineage enriched" "Detected in single" 14 "dendritic cells: 2.5" "Cell line enhanced" "Detected in many" "A-431: 8.6;HeLa: 10.0;hTERT-HME1: 9.2;SiHa: 8.9;SK-BR-3: 7.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA046348 Enhanced Approved Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA046348: AB_10966145" "unprognostic (1.96e-1)" "unprognostic (3.40e-1)" "unprognostic (1.21e-3)" "unprognostic (2.37e-2)" "unprognostic (2.54e-2)" "unprognostic (1.38e-1)" "unprognostic (5.33e-2)" "unprognostic (4.55e-2)" "unprognostic (1.52e-1)" "unprognostic (7.21e-3)" "unprognostic (1.30e-3)" "unprognostic (2.39e-1)" "unprognostic (1.51e-12)" "unprognostic (2.41e-2)" "unprognostic (2.34e-1)" "unprognostic (2.21e-1)" "unprognostic (1.28e-1)" 0.6 1.3 0.8 0.3 0.7 1.8 4.4 13.8 1.2 3.2 32.3 3.3 1.9 1.6 4.0 7.8 2.7 0.9 3.4 1.2 0.0 3.4 0.7 1.9 0.2 0.6 0.6 2.4 10.2 8.3 1.3 0.5 0.8 2.2 3.4 6.7 4.7 1.5 34.5 13.4 2.0 1.1 0.3 0.5 2.5 3.4 0.4 1.5 6.8 16.5 2.3 2.2 3.4 0.2 8.6 0.7 0.0 0.2 0.0 0.1 2.9 0.3 1.4 0.8 0.2 3.6 3.0 0.0 0.8 0.3 2.6 7.4 2.1 6.1 0.9 0.0 3.3 0.0 10.0 0.9 0.0 0.0 0.2 0.2 7.0 0.0 9.2 2.4 0.2 0.7 0.0 0.0 0.5 1.2 0.0 0.0 2.8 2.8 0.8 0.0 2.0 0.2 5.1 5.5 1.2 0.4 8.9 7.8 0.2 2.2 3.3 0.0 0.0 0.4 3.7 0.2 1.4 0.0 0.0 0.0 1.8 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.8 0.7 13.8 1.2 1.2 0.0 0.6 0.6 0.8 0.3 0.4 0.2 0.1 3.2 2.0 1.3 0.0 11.9 6.6 2.9 10.8 0.1 2.7 1.9 1.8 0.0 5.2 0.0 0.0 0.3 0.5 5.9 0.0 1.6 3.3 5.9 0.6 0.4 0.0 0.0 15.8 1.8 0.6 0.6 6.1 10.8 1.3 0.3 0.0 0.5 0.3 8.4 2.4 2.3 0.0 0.0 2.1 1.5 0.0 0.6 0.0 1.0 0.0 2.5 0.0 19.1 1.3 1.9 0.3 0.0 1.4 7.9 2.2 0.7 1.3 4.7 0.0 1.0 0.4 6.1 5.8 11.6 14.5 1.6 0.2 0.3 1.8 8.6 FAM185A MGC35361 ENSG00000222011 "Family with sequence similarity 185 member A" Q8N0U4 7 102748971-102809225 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 64.0;Excitatory neurons: 132.4;Inhibitory neurons: 134.5;Microglial cells: 63.7;Oligodendrocyte precursor cells: 70.9;Oligodendrocytes: 89.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPMI-8226: 6.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020470, HPA029883" Uncertain Approved Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA020470: AB_1853890, HPA029883: AB_10601903" "unprognostic (8.28e-2)" "unprognostic (2.28e-1)" "unprognostic (8.19e-2)" "unprognostic (1.20e-1)" "unprognostic (3.88e-3)" "unprognostic (6.06e-2)" "unprognostic (1.63e-2)" "unprognostic (1.59e-3)" "unprognostic (3.97e-2)" "unprognostic (4.45e-2)" "unprognostic (7.11e-2)" "unprognostic (2.03e-1)" "prognostic favorable (9.36e-5)" "unprognostic (3.64e-2)" "unprognostic (2.65e-1)" "unprognostic (2.13e-3)" "unprognostic (5.25e-2)" 0.8 1.1 0.6 0.6 0.6 0.8 0.8 1.0 0.8 1.3 0.6 1.0 0.4 0.8 0.4 1.0 0.7 0.4 1.0 0.4 0.5 1.2 2.8 0.6 0.4 0.5 0.8 1.0 1.3 1.5 0.7 0.5 0.4 1.2 0.7 1.1 0.8 0.8 3.5 1.2 0.8 0.5 0.3 0.6 1.9 0.4 0.7 0.7 0.9 2.0 0.4 1.3 1.0 1.2 0.6 2.0 0.4 2.4 0.4 0.9 1.5 0.6 1.3 0.3 0.0 1.7 2.1 0.6 0.9 0.6 1.5 2.3 1.0 0.9 0.4 1.2 0.1 0.2 0.2 2.8 0.6 0.9 1.1 0.0 1.8 0.0 0.4 1.5 0.6 0.5 1.0 1.1 1.1 3.2 2.1 0.6 0.9 2.7 0.5 0.2 0.0 6.7 0.2 1.4 0.4 1.7 4.0 4.5 0.1 0.0 2.7 0.0 1.6 0.2 1.1 2.1 0.4 3.1 1.4 0.6 0.4 0.6 0.2 0.0 1.4 1.9 1.1 1.2 1.1 2.2 0.7 1.0 1.6 0.8 0.9 0.7 3.7 0.8 0.5 1.2 0.8 0.4 0.6 0.6 1.0 0.8 0.4 0.5 0.5 0.8 0.4 0.3 0.7 1.2 2.9 3.2 1.5 64.0 5.1 4.2 8.1 5.8 9.6 8.8 5.1 3.6 6.3 11.5 6.0 0.0 10.4 13.8 5.6 2.0 19.6 4.6 5.4 5.0 3.8 4.0 1.2 9.4 132.4 2.3 6.5 4.0 9.2 4.1 0.0 7.0 6.4 7.4 4.4 5.0 134.5 3.2 6.1 2.8 1.4 3.3 7.2 3.3 7.2 63.7 3.2 4.9 2.1 70.9 89.2 2.5 1.7 5.3 6.3 3.8 4.6 11.1 3.0 21.4 13.1 4.3 4.1 9.2 5.1 6.7 4.5 8.1 4.1 7.0 3.6 7.0 FAM187A ENSG00000214447 "Family with sequence similarity 187 member A" A6NFU0 17 44899712-44905390 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 15.0;testis: 15.9" "Cell type enriched" "Detected in single" 36 "Respiratory ciliated cells: 3.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 13.7;U-87 MG: 16.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA043131 Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA043131: AB_10796686" 0.5 1.9 2.0 0.4 2.5 0.5 1.2 1.4 3.0 1.5 3.6 0.8 0.1 0.8 2.3 0.4 15.0 0.8 0.3 2.3 2.7 2.8 0.3 1.1 0.5 2.6 4.3 1.3 1.3 1.7 2.2 0.1 2.9 0.6 0.7 5.4 0.5 1.0 0.2 0.4 0.3 0.5 2.6 0.2 0.4 15.9 3.1 0.4 3.4 0.1 0.4 0.6 0.3 2.1 1.2 5.6 2.3 1.5 2.5 3.2 1.3 0.5 4.9 2.5 3.3 2.4 4.8 0.2 1.4 1.6 4.6 5.4 0.7 1.9 1.3 5.9 1.4 0.8 2.8 0.7 1.3 1.1 0.7 0.7 2.5 4.5 1.0 4.8 1.2 1.0 1.4 0.2 0.6 1.3 0.1 1.3 0.9 3.0 1.1 0.9 0.1 0.4 13.7 0.7 6.9 1.3 0.5 0.1 1.0 1.1 5.8 1.1 0.5 1.0 1.4 1.3 1.1 0.1 0.2 0.5 16.0 0.8 1.1 0.0 0.8 0.5 0.0 0.2 0.0 0.0 0.0 0.2 0.5 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.5 2.0 2.5 1.4 3.0 2.3 2.7 2.6 4.3 2.9 2.6 3.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM221A "C7orf46, DKFZp686F0810, FLJ45875, MGC72075" ENSG00000188732 "Family with sequence similarity 221 member A" A4D161 7 23680130-23703249 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 69.2;Respiratory ciliated cells: 51.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 19.3;GAMG: 26.5;MOLT-4: 27.4;SCLC-21H: 23.4;SH-SY5Y: 41.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA019719, HPA026748, HPA026752" Enhanced Approved Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 22: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA019719: AB_1853910, HPA026748: AB_1853911, HPA026752: AB_1853912" "unprognostic (1.28e-1)" "unprognostic (7.28e-3)" "unprognostic (6.03e-3)" "unprognostic (2.54e-1)" "unprognostic (3.33e-2)" "unprognostic (8.04e-2)" "unprognostic (8.51e-3)" "unprognostic (2.18e-3)" "unprognostic (3.10e-2)" "unprognostic (5.69e-2)" "unprognostic (3.75e-1)" "unprognostic (2.42e-2)" "unprognostic (9.30e-3)" "unprognostic (4.26e-2)" "unprognostic (1.11e-2)" "unprognostic (2.40e-1)" "unprognostic (1.81e-2)" 5.5 3.6 14.9 3.2 17.2 1.7 4.3 18.2 24.4 3.5 15.4 6.5 9.9 2.5 3.4 7.2 9.3 3.4 4.1 14.2 15.7 6.4 9.7 4.7 3.8 17.3 16.1 3.8 20.4 2.7 5.3 1.6 18.1 4.8 8.5 4.8 7.5 2.4 2.6 3.9 7.3 1.9 16.7 2.6 11.9 19.7 16.2 7.7 6.0 4.3 4.9 4.9 4.1 23.8 0.0 1.0 11.1 8.9 0.4 0.0 5.4 0.6 0.8 1.4 1.6 11.6 5.5 1.5 19.3 0.3 26.5 2.4 0.0 0.1 2.2 0.0 15.3 3.3 1.1 0.0 3.0 0.0 17.3 0.7 0.7 0.2 0.1 2.4 3.4 11.7 0.0 0.0 0.4 5.5 27.4 0.0 0.0 0.0 5.8 10.8 1.1 0.0 5.8 5.4 23.4 41.3 1.9 0.0 0.0 2.6 5.6 8.0 0.5 0.1 4.2 2.4 1.1 0.1 0.1 0.0 1.1 0.0 2.0 0.0 3.1 4.2 5.1 2.0 10.7 6.6 8.6 6.4 5.4 6.8 9.8 5.5 0.1 7.8 6.0 4.7 12.2 3.3 14.9 17.2 18.2 24.4 14.2 15.7 17.3 16.1 18.1 16.7 16.2 23.8 7.2 16.0 7.2 13.4 7.2 16.2 9.5 10.0 14.8 6.9 17.8 7.7 5.5 20.0 20.0 7.3 2.1 3.5 5.3 8.2 9.8 15.4 8.5 24.7 2.0 6.9 14.9 3.8 13.7 10.6 0.3 12.3 36.7 11.2 5.1 10.2 6.1 16.0 6.7 6.7 16.3 25.7 18.3 4.1 10.8 10.4 4.7 6.1 8.8 12.2 2.1 8.5 2.1 11.6 69.2 11.5 25.2 3.8 7.1 11.7 15.2 12.3 51.6 8.0 19.7 8.5 5.3 45.2 27.6 14.6 18.9 0.8 7.6 4.4 22.5 11.8 FAM43B FLJ44952 ENSG00000183114 "Family with sequence similarity 43 member B" Q6ZT52 1 20552573-20555020 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 21.0;brain: 21.7" "Cell type enhanced" "Detected in some" "Astrocytes: 4.6;Distal tubular cells: 3.9;Excitatory neurons: 2.6;Fibroblasts: 3.8;Inhibitory neurons: 7.5" "Cancer enhanced" "Detected in some" "glioma: 4.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 3.3;BJ hTERT+: 2.4;fHDF/TERT166: 4.9;Hep G2: 3.7;SCLC-21H: 4.3;SiHa: 8.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA050813 Approved Approved Cytosol NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA050813: AB_2681244" "unprognostic (1.51e-1)" "unprognostic (5.85e-2)" "unprognostic (2.80e-3)" "unprognostic (1.48e-1)" "unprognostic (5.97e-3)" "unprognostic (1.74e-1)" "unprognostic (8.33e-2)" "unprognostic (5.87e-4)" "unprognostic (1.86e-2)" "unprognostic (7.46e-2)" "unprognostic (8.85e-3)" "unprognostic (2.73e-1)" "unprognostic (1.78e-4)" "unprognostic (1.06e-2)" "unprognostic (6.05e-3)" "unprognostic (6.48e-2)" "unprognostic (2.12e-2)" 1.6 21.0 12.2 0.2 10.7 0.0 0.3 11.0 12.5 0.6 2.4 0.9 0.1 1.0 3.0 0.3 0.9 0.2 3.9 13.5 13.5 5.0 0.4 0.3 0.0 16.6 21.7 0.3 0.5 0.0 0.8 0.6 13.8 0.7 0.1 0.4 0.5 0.1 0.9 0.2 0.3 0.8 9.9 0.8 0.3 0.5 18.8 0.1 1.2 1.4 0.0 0.7 0.4 10.2 0.0 1.7 0.2 3.3 0.1 0.1 0.0 0.3 2.4 0.4 0.0 0.1 0.0 0.0 0.2 4.9 0.8 0.0 0.5 0.0 0.0 0.0 0.7 0.1 0.2 3.7 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.3 0.5 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 10.7 11.0 12.5 13.5 13.5 16.6 21.7 13.8 9.9 18.8 10.2 0.1 0.0 0.0 4.6 0.0 0.0 0.0 0.0 1.2 1.8 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.1 0.1 1.9 1.6 0.0 0.0 2.6 0.0 0.1 3.8 0.0 0.2 0.0 0.0 1.8 0.0 0.1 0.0 7.5 0.0 0.0 0.6 0.0 0.1 0.3 0.1 0.0 1.0 0.0 0.7 0.0 0.5 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.5 0.3 0.1 0.9 0.7 0.0 0.0 0.1 0.1 0.1 0.0 FAM53B "bA12J10.2, KIAA0140, smp" ENSG00000189319 "Family with sequence similarity 53 member B" Q14153 10 124619292-124744378 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 79.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "SK-MEL-30: 60.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037751, HPA037752" Approved Approved Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "HPA037751: AB_2675645, HPA037752: AB_10672285" "unprognostic (7.88e-2)" "prognostic favorable (4.96e-4)" "unprognostic (1.73e-2)" "unprognostic (2.92e-1)" "unprognostic (4.91e-1)" "prognostic favorable (1.97e-4)" "unprognostic (2.52e-2)" "unprognostic (5.03e-3)" "unprognostic (1.51e-2)" "unprognostic (4.02e-2)" "prognostic favorable (7.00e-6)" "unprognostic (1.93e-1)" "prognostic favorable (4.81e-7)" "prognostic favorable (3.26e-4)" "unprognostic (3.41e-1)" "unprognostic (2.03e-1)" "unprognostic (2.45e-2)" 12.6 19.2 21.6 14.3 33.3 25.8 8.3 18.1 30.5 12.8 8.4 12.4 15.4 23.6 3.9 13.2 11.2 5.7 18.9 21.1 16.5 10.6 4.2 10.7 31.0 30.3 25.6 19.1 7.2 12.4 12.7 4.9 22.7 8.9 7.1 6.3 15.2 7.0 55.0 14.4 17.1 12.8 17.3 20.1 9.6 15.6 35.9 32.9 16.2 22.3 21.7 8.6 8.0 51.7 10.7 12.5 9.6 27.5 11.3 5.8 26.2 4.8 6.7 5.6 4.9 6.6 6.7 37.2 9.7 6.5 5.5 20.8 12.7 15.4 2.4 44.6 13.2 18.1 6.3 16.7 7.6 16.6 11.8 5.6 16.2 5.2 8.3 7.0 9.1 21.2 13.2 17.0 5.5 20.4 18.7 22.4 5.9 9.5 10.9 32.9 3.6 18.2 4.6 19.3 12.8 12.2 4.7 17.8 60.2 3.8 7.2 21.8 5.0 6.7 5.5 6.6 10.7 2.7 5.3 23.8 5.1 13.6 3.8 0.8 2.2 2.2 6.9 2.1 3.3 3.5 3.0 3.7 1.4 6.0 1.2 2.0 3.2 0.7 2.6 1.9 3.6 3.4 21.6 33.3 18.1 30.5 21.1 16.5 30.3 25.6 22.7 17.3 35.9 51.7 13.4 9.6 12.6 14.0 22.4 3.6 5.9 8.5 12.5 6.1 4.3 2.4 17.9 1.5 6.7 3.7 10.4 4.7 31.5 25.9 1.9 3.1 19.4 12.9 18.6 8.7 15.0 8.6 27.1 4.0 4.9 6.0 6.6 8.3 5.1 9.0 16.8 3.7 13.3 1.7 15.0 17.4 10.2 27.8 5.1 6.2 5.6 16.4 8.8 24.4 14.5 4.5 30.9 16.1 79.4 2.8 12.2 10.5 20.0 3.7 22.4 4.3 14.1 25.6 0.0 9.8 4.6 7.0 8.6 12.1 5.7 0.8 21.4 6.9 15.3 6.7 FAM71F1 "FAM137A, NYD-SP18" ENSG00000135248 "Family with sequence similarity 71 member F1" Q96KD3 7 128709061-128731743 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 88 "testis: 93.9" "Group enriched" "Detected in some" 93 "Early spermatids: 1122.8;Late spermatids: 2008.1" "Cancer enriched" "Detected in single" 23 "testis cancer: 4.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "NTERA-2: 16.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA020636 Uncertain Cytosol No NA "Cluster 74: Testis - Spermatogenesis" "Cluster 5: NTERA-2 - Transcription" "Cluster 34: Spermatids - Unknown function" Cytosol "HPA020636: AB_1854739" "unprognostic (3.09e-2)" "unprognostic (3.39e-3)" "unprognostic (6.03e-2)" "unprognostic (5.25e-1)" "unprognostic (2.97e-1)" "unprognostic (1.20e-1)" "unprognostic (4.67e-2)" "unprognostic (2.17e-1)" "unprognostic (1.95e-2)" "unprognostic (1.00e-5)" "unprognostic (1.48e-1)" "unprognostic (2.18e-6)" "unprognostic (6.97e-2)" "unprognostic (2.09e-1)" "unprognostic (2.19e-3)" "unprognostic (1.99e-1)" 0.0 0.0 0.8 0.0 0.7 0.0 0.1 0.4 0.9 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.7 0.6 0.4 0.0 0.1 0.0 0.6 1.0 0.0 0.1 0.0 0.5 0.0 0.8 0.2 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.0 93.9 1.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.2 1.4 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 0.4 0.9 0.7 0.6 0.6 1.0 0.8 0.5 1.0 0.6 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.1 0.3 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 1122.8 0.2 0.1 0.6 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.0 0.0 2008.1 12.8 0.7 0.0 0.0 0.0 0.3 0.0 0.5 0.4 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.8 0.1 16.7 6.8 0.0 0.1 1.2 0.0 0.5 0.0 0.0 FAM83G "FLJ41564, PAWS1" ENSG00000188522 "Family with sequence similarity 83 member G" A6ND36 17 18968789-19004764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 51.3;skin 1: 67.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 77.8;Basal squamous epithelial cells: 39.3;Distal enterocytes: 46.5;Squamous epithelial cells: 55.3;Suprabasal keratinocytes: 68.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 22.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA023369, HPA023940" Enhanced Approved Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA023369: AB_1848415, HPA023940: AB_1848416" "unprognostic (2.12e-2)" "unprognostic (5.90e-2)" "unprognostic (1.17e-1)" "unprognostic (9.48e-2)" "unprognostic (1.42e-3)" "unprognostic (2.04e-2)" "prognostic unfavorable (8.29e-4)" "unprognostic (1.07e-3)" "unprognostic (1.14e-1)" "unprognostic (2.03e-2)" "unprognostic (1.17e-1)" "unprognostic (3.51e-2)" "unprognostic (5.65e-2)" "prognostic favorable (7.58e-6)" "unprognostic (9.68e-2)" "unprognostic (5.13e-2)" "unprognostic (3.74e-2)" 2.3 2.2 0.8 2.9 0.8 1.4 2.8 0.8 1.2 10.8 2.1 8.2 10.8 2.5 0.9 51.3 1.6 6.4 17.2 0.8 1.9 7.1 21.7 3.2 3.0 1.6 1.4 1.4 9.5 6.4 4.3 0.7 2.7 3.5 5.3 0.2 10.9 2.2 6.9 67.3 11.3 1.5 0.9 2.0 9.8 1.0 1.4 3.7 5.6 0.8 5.7 2.5 17.0 0.7 24.7 22.4 0.2 0.0 0.7 2.0 35.9 25.2 11.0 21.0 15.7 28.7 8.8 16.1 15.1 16.7 17.1 28.6 3.6 21.1 9.6 13.2 8.1 0.4 11.2 15.9 15.3 2.9 7.9 2.8 38.9 13.6 22.3 7.9 7.6 2.5 7.7 0.5 6.0 15.0 0.7 6.0 11.0 34.1 0.1 0.1 0.0 7.8 10.1 6.2 11.2 0.0 8.7 5.3 1.5 29.1 9.2 3.6 14.2 12.9 21.6 6.1 29.8 2.2 4.0 4.1 10.1 0.1 8.6 1.1 0.0 0.0 0.7 0.0 0.3 0.3 0.4 0.2 0.0 0.3 0.3 0.0 0.0 0.0 0.2 0.0 0.5 0.2 0.8 0.8 0.8 1.2 0.8 1.9 1.6 1.4 2.7 0.9 1.4 0.7 0.6 3.2 2.2 0.0 2.5 77.8 12.2 9.9 39.3 0.2 7.1 2.9 5.1 11.5 6.3 7.3 0.0 0.4 0.7 46.5 0.0 15.8 0.1 2.4 1.0 1.9 7.1 2.7 0.1 10.0 9.7 2.6 17.3 5.0 8.9 3.5 1.1 20.9 1.2 0.0 0.1 17.7 8.2 0.3 7.8 1.9 0.0 1.0 5.4 0.0 1.0 0.2 3.1 0.5 0.0 24.3 22.8 0.0 3.0 13.2 15.3 4.4 2.5 0.4 0.0 1.3 2.0 0.1 1.0 55.3 68.5 1.9 2.6 0.0 17.1 9.1 FAM83H FLJ46072 ENSG00000180921 "Family with sequence similarity 83 member H" Q6ZRV2 8 143723933-143738234 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 70.5;skin 1: 34.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 58.7;hTCEpi: 59.8;MCF7: 118.2;OE19: 62.4;RT4: 70.1;T-47d: 58.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA024505, HPA024604" Enhanced Approved Cytosol NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA024505: AB_1848417, HPA024604: AB_1848418" "unprognostic (3.80e-2)" "unprognostic (3.75e-3)" "unprognostic (6.87e-2)" "unprognostic (1.63e-2)" "unprognostic (3.10e-2)" "unprognostic (1.17e-1)" "unprognostic (1.88e-2)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.93e-1)" "unprognostic (2.40e-1)" "unprognostic (2.24e-3)" "unprognostic (3.95e-2)" "unprognostic (9.69e-3)" "prognostic favorable (4.42e-4)" "unprognostic (5.54e-1)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" 2.1 4.0 1.9 2.1 1.7 0.5 4.4 1.2 2.2 11.5 2.6 9.8 8.4 0.8 3.3 70.5 4.7 3.3 0.8 2.0 1.1 11.8 13.5 6.3 0.9 1.6 2.4 0.3 13.9 7.9 5.9 3.5 1.5 7.2 4.3 1.1 17.1 3.8 0.1 34.9 9.1 0.3 1.3 1.7 11.0 2.8 1.5 1.5 14.1 0.0 4.0 8.3 23.2 2.2 47.0 28.3 0.3 0.1 0.1 0.0 16.6 4.0 0.0 2.0 0.7 25.8 53.4 0.0 6.1 1.0 0.0 56.1 3.5 51.9 0.9 0.0 0.2 1.5 58.7 18.3 4.3 0.6 1.7 2.9 59.8 0.2 15.0 0.8 0.0 4.2 22.2 0.1 0.0 118.2 0.8 0.4 4.8 62.4 15.3 0.1 0.1 6.0 16.5 70.1 7.1 0.2 38.3 53.8 7.8 7.5 58.2 8.2 0.3 0.1 7.2 3.9 0.2 0.0 0.0 0.2 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.7 1.2 2.2 2.0 1.1 1.6 2.4 1.5 1.3 1.5 2.2 0.1 32.1 16.5 0.7 0.6 22.8 17.7 21.9 6.8 2.0 18.2 14.0 4.6 14.3 18.9 29.5 2.1 12.8 0.5 38.5 3.9 22.0 1.2 11.4 2.9 1.0 14.4 0.0 1.3 25.9 17.8 1.6 25.0 25.9 0.0 5.4 0.7 25.5 4.7 10.1 0.5 24.3 16.2 2.8 0.8 0.7 0.0 1.3 1.8 0.0 2.8 6.6 2.1 0.5 0.1 42.7 27.2 0.4 0.4 26.4 23.6 7.0 17.4 2.0 0.0 0.2 1.9 1.7 1.0 38.9 26.9 14.6 0.9 1.2 27.8 33.9 FARP1 "CDEP, MGC87400, PLEKHC2, PPP1R75" ENSG00000152767 "FERM, ARH/RhoGEF and pleckstrin domain protein 1" Q9Y4F1 13 98142562-98455176 "Predicted intracellular proteins" "Developmental protein, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 191.3;Early spermatids: 207.8;Inhibitory neurons: 176.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 125.3;Hep G2: 130.5;SuSa: 110.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000760 Approved Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 36: Stromal cells - Cell proliferation" Cytosol "HPA000760: AB_1078816" "unprognostic (4.78e-3)" "unprognostic (1.65e-1)" "unprognostic (3.07e-1)" "unprognostic (2.01e-1)" "unprognostic (1.10e-2)" "unprognostic (2.30e-1)" "unprognostic (7.73e-2)" "unprognostic (6.91e-2)" "unprognostic (1.03e-1)" "unprognostic (6.09e-2)" "unprognostic (3.13e-1)" "unprognostic (1.08e-1)" "prognostic favorable (1.39e-5)" "unprognostic (4.89e-2)" "unprognostic (2.27e-1)" "unprognostic (2.18e-2)" "unprognostic (4.18e-2)" 17.9 35.3 40.7 10.1 43.9 1.5 24.4 24.9 40.8 26.4 18.7 41.8 8.0 19.8 23.7 8.9 18.4 18.5 13.7 42.5 37.9 68.7 67.8 32.8 6.9 35.5 35.3 16.2 45.0 14.2 23.1 28.2 30.2 41.2 12.6 8.9 37.2 25.7 19.7 14.0 13.6 23.4 35.6 13.0 32.9 14.0 38.9 3.3 43.9 15.1 3.7 27.0 16.1 28.6 0.7 10.7 47.1 66.7 13.3 26.0 22.7 72.0 46.9 39.8 34.8 83.9 31.9 0.2 27.0 125.3 9.8 1.5 20.1 19.9 66.4 1.3 20.5 0.4 38.9 130.5 35.3 0.3 0.6 30.6 8.9 11.6 2.6 23.0 26.5 1.0 0.1 0.7 27.8 18.6 2.8 0.4 22.5 40.7 12.5 25.4 18.3 1.4 88.0 46.8 20.0 43.5 8.8 18.9 51.0 110.8 26.9 0.1 25.6 42.8 16.1 29.2 37.0 0.7 0.7 0.5 19.9 1.4 30.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.7 43.9 24.9 40.8 42.5 37.9 35.5 35.3 30.2 35.6 38.9 28.6 37.3 44.8 24.8 191.3 2.6 6.9 60.2 8.8 15.4 13.9 73.3 40.8 8.4 123.0 27.5 57.0 45.9 6.7 4.0 10.9 80.3 47.5 207.8 70.3 90.5 23.9 31.1 2.7 75.3 35.1 6.4 29.9 23.4 100.7 13.3 44.5 23.2 58.4 53.5 30.3 176.4 10.1 24.4 22.7 9.3 125.9 19.0 14.0 28.4 44.0 17.5 29.6 2.1 104.5 3.7 47.0 4.4 29.3 3.1 56.8 0.3 139.6 38.6 15.7 19.7 18.7 55.4 9.2 15.9 3.2 2.8 4.5 6.4 60.4 12.6 47.2 FARP2 "FIR, FRG, KIAA0793, PLEKHC3" ENSG00000006607 "FERM, ARH/RhoGEF and pleckstrin domain protein 2" O94887 2 241356285-241494841 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 128.2;Oligodendrocytes: 114.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031226, HPA055592" Approved Approved Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "HPA031226: AB_10602808, HPA055592: AB_2682856" "unprognostic (3.07e-1)" "unprognostic (1.39e-1)" "unprognostic (3.75e-2)" "unprognostic (1.07e-2)" "unprognostic (2.51e-1)" "unprognostic (1.37e-2)" "unprognostic (1.60e-2)" "unprognostic (1.70e-1)" "unprognostic (1.83e-1)" "unprognostic (2.19e-1)" "unprognostic (1.71e-1)" "unprognostic (1.90e-1)" "unprognostic (9.11e-2)" "unprognostic (6.31e-2)" "unprognostic (6.78e-2)" "unprognostic (2.74e-1)" "unprognostic (1.73e-1)" 9.6 10.3 13.8 11.4 16.8 5.4 9.0 19.3 16.0 10.0 9.8 22.6 20.2 10.6 7.3 14.1 9.2 10.0 7.6 13.2 12.9 11.0 17.1 10.4 11.9 15.6 15.2 11.0 11.4 13.2 8.4 9.0 15.6 10.1 21.3 10.1 9.2 10.0 10.6 22.6 18.9 11.6 11.7 11.6 20.3 28.1 16.2 8.5 6.8 9.9 13.8 14.2 10.1 21.3 20.0 14.3 25.8 17.7 21.9 29.1 23.1 19.7 16.3 20.0 20.6 15.3 23.4 8.5 5.2 38.8 14.1 22.4 35.0 20.6 30.4 13.3 18.1 18.8 25.4 20.3 16.0 17.0 14.1 29.3 15.2 29.2 23.7 9.3 18.4 16.1 21.7 7.6 16.3 16.7 18.3 12.5 12.8 35.3 11.1 20.3 58.2 25.7 25.9 41.0 30.5 20.3 22.1 15.4 59.5 14.9 8.1 16.8 27.9 18.8 14.3 23.8 16.0 13.0 10.0 18.8 17.2 11.5 39.0 6.1 2.1 7.3 1.3 5.1 1.2 4.4 1.4 1.5 3.1 4.9 0.9 1.0 1.3 1.7 2.8 6.4 2.2 1.6 13.8 16.8 19.3 16.0 13.2 12.9 15.6 15.2 15.6 11.7 16.2 21.3 8.9 28.9 5.9 27.4 23.9 15.4 11.4 8.0 16.5 12.7 11.1 8.3 29.6 14.3 12.3 18.4 18.8 5.8 9.7 36.3 3.9 9.3 42.7 12.0 10.6 10.5 28.1 3.4 43.1 12.3 5.4 12.9 45.3 14.0 6.3 15.9 11.0 11.6 4.2 20.2 36.7 38.7 10.2 8.4 9.4 25.0 14.9 11.9 39.2 38.4 8.5 4.9 2.1 128.2 114.0 12.6 24.1 10.5 14.4 12.8 20.9 7.1 17.3 15.1 19.7 21.4 14.1 45.6 19.7 13.8 15.2 11.1 6.0 11.3 26.2 22.4 FARSA "CML33, FARSL, FARSLA" ENSG00000179115 "Phenylalanyl-tRNA synthetase subunit alpha" Q9Y285 19 12922479-12934037 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001911 Enhanced Approved Cytosol NA NA 55000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA001911: AB_1848427" "unprognostic (1.52e-1)" "prognostic favorable (8.23e-4)" "unprognostic (2.71e-1)" "prognostic unfavorable (9.22e-4)" "unprognostic (1.16e-2)" "unprognostic (1.28e-1)" "unprognostic (4.93e-3)" "unprognostic (5.76e-2)" "unprognostic (2.86e-1)" "unprognostic (1.24e-1)" "unprognostic (1.21e-1)" "unprognostic (1.45e-2)" "unprognostic (1.45e-3)" "prognostic favorable (8.32e-4)" "unprognostic (2.59e-1)" "unprognostic (8.25e-2)" "unprognostic (1.84e-2)" 26.4 32.5 30.1 29.4 32.2 31.6 25.0 28.1 40.0 21.8 19.4 29.1 26.2 24.3 12.1 39.2 24.0 16.4 37.4 33.4 32.7 29.1 40.6 20.7 36.0 32.6 31.8 23.1 36.3 30.4 32.1 22.5 33.4 25.5 17.1 14.7 30.4 21.7 57.0 33.3 26.5 17.7 24.3 32.0 30.6 22.6 30.6 33.0 25.5 30.6 25.4 30.6 25.6 31.1 135.7 125.6 49.3 106.9 33.4 31.4 88.9 93.6 60.8 133.0 103.9 154.2 56.1 148.7 147.1 54.1 53.9 101.9 121.0 108.4 48.1 87.9 183.7 117.0 106.8 124.2 108.4 227.7 147.8 43.4 78.7 102.8 82.1 43.8 73.1 148.7 179.6 30.6 56.7 181.5 273.4 283.5 154.2 83.4 210.6 139.5 51.2 191.4 70.5 78.7 153.8 141.4 64.2 109.2 69.0 23.0 85.9 137.5 71.3 108.0 47.8 165.6 180.6 199.6 186.5 156.8 97.7 203.4 114.1 66.6 111.0 86.3 87.1 119.0 108.2 88.2 85.1 81.4 120.4 94.5 85.4 82.3 7.0 118.0 92.8 97.0 87.6 130.2 30.1 32.2 28.1 40.0 33.4 32.7 32.6 31.8 33.4 24.3 30.6 31.1 15.0 9.6 21.4 9.1 24.7 25.4 28.0 63.4 20.5 25.1 18.8 18.5 25.7 14.3 35.4 23.9 10.4 87.5 17.5 26.7 58.7 55.4 5.8 16.0 18.6 20.0 22.8 61.8 12.1 46.4 78.7 18.4 27.5 15.8 23.5 26.3 21.0 25.8 62.9 18.5 12.8 32.6 69.2 23.5 21.2 9.4 19.0 19.7 33.8 1.9 45.5 23.6 25.7 8.5 7.5 47.0 26.3 13.2 40.9 32.6 30.4 55.7 22.3 17.1 6.6 16.5 24.3 20.2 41.9 26.3 29.5 96.7 22.5 28.9 44.7 26.8 FAT4 "CDHF14, CDHR11, FAT-J" ENSG00000196159 "FAT atypical cadherin 4" Q6V0I7 4 125314918-125492932 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 19.3;Endothelial cells: 18.0;Fibroblasts: 17.9;Hepatic stellate cells: 33.2;Inhibitory neurons: 35.0;Microglial cells: 23.4;Oligodendrocytes: 54.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 15.5;ASC TERT1: 11.2;fHDF/TERT166: 11.4;HSkMC: 13.6;HUVEC TERT2: 14.3;TIME: 21.9" "Low region specificity" "Detected in many" HPA052819 Approved Approved Cytosol NA NA 2300000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA052819: AB_2681963" "unprognostic (1.18e-1)" "unprognostic (1.77e-1)" "unprognostic (7.99e-2)" "unprognostic (1.09e-1)" "unprognostic (2.31e-1)" "unprognostic (2.81e-4)" "unprognostic (6.17e-3)" "unprognostic (1.28e-1)" "unprognostic (1.77e-2)" "unprognostic (2.78e-2)" "unprognostic (1.63e-1)" "unprognostic (1.39e-1)" "prognostic favorable (1.89e-4)" "unprognostic (2.38e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-2)" "unprognostic (2.49e-3)" 3.3 1.0 3.2 1.4 4.1 0.0 2.7 1.2 2.7 4.0 0.7 6.4 0.9 3.0 1.3 2.3 1.9 4.3 4.0 3.8 2.0 2.8 2.5 4.5 0.8 3.1 2.8 4.9 0.9 3.0 0.6 2.9 2.8 3.7 2.3 0.5 1.0 2.6 1.6 1.4 2.2 3.5 3.5 2.7 2.0 0.7 3.3 1.1 4.0 4.8 0.8 2.5 1.8 4.8 0.0 0.9 7.4 0.8 15.5 11.2 0.0 2.6 3.0 1.2 1.2 0.0 0.4 0.0 3.1 11.4 1.5 0.0 2.8 3.2 0.7 0.0 1.3 1.7 3.3 0.1 5.4 1.1 0.0 13.6 1.9 0.7 7.0 9.1 14.3 0.0 0.0 1.9 6.7 0.1 0.5 0.0 0.5 0.0 0.3 0.9 1.5 0.0 0.1 0.0 0.2 1.5 0.4 0.0 0.0 0.4 0.0 0.0 21.9 7.8 2.2 2.7 1.1 0.3 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.2 4.1 1.2 2.7 3.8 2.0 3.1 2.8 2.8 3.5 3.3 4.8 19.3 6.4 0.0 8.8 0.0 1.7 0.2 1.5 0.0 3.7 0.3 1.3 6.9 0.0 0.3 5.5 0.0 0.1 0.9 0.0 0.0 0.7 0.9 0.6 8.8 18.0 0.0 0.0 9.4 0.2 0.0 17.9 1.1 1.0 0.0 1.2 33.2 7.4 0.2 0.0 35.0 0.0 0.0 2.2 2.2 0.2 5.9 0.3 3.6 23.4 0.0 1.1 1.0 6.0 54.4 0.3 0.0 4.9 1.4 0.4 0.0 0.7 0.1 0.2 0.0 5.3 4.1 0.1 0.6 0.5 0.6 0.0 0.3 5.7 0.0 0.1 FBN1 "FBN, MASS, MFS1, OCTD, SGS, WMS" ENSG00000166147 "Fibrillin 1" P35555 15 48408313-48645721 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Heparin-binding, Hormone" "Aortic aneurysm, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 60.9;placenta: 76.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 132.4;Fibroblasts: 388.5;Leydig cells: 236.1;Oligodendrocytes: 218.7;Peritubular cells: 227.2;Skeletal myocytes: 139.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 215.1;ASC TERT1: 460.7;fHDF/TERT166: 420.8;HSkMC: 251.3;hTERT-RPE1: 211.1;U-138 MG: 206.9;U-2197: 305.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002670, HPA017759, HPA021057, CAB058696, CAB068188" Enhanced Approved Cytosol "Secreted to blood" NA NA 520000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "CAB002670: , CAB058696: AB_2665596, CAB068188: AB_2665597, HPA017759: AB_1848584, HPA021057: AB_1848586" "unprognostic (3.97e-2)" "unprognostic (1.55e-2)" "unprognostic (2.40e-2)" "unprognostic (9.50e-2)" "unprognostic (1.51e-1)" "unprognostic (9.49e-2)" "unprognostic (2.00e-2)" "unprognostic (4.79e-2)" "unprognostic (7.82e-2)" "unprognostic (1.50e-2)" "unprognostic (2.78e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (7.44e-5)" "prognostic unfavorable (6.57e-4)" "unprognostic (1.25e-2)" "unprognostic (8.69e-3)" "prognostic unfavorable (5.11e-4)" 60.9 4.4 1.4 14.5 5.4 3.4 13.7 2.8 2.8 36.0 9.5 8.3 3.8 15.2 6.3 12.6 12.2 27.3 23.5 0.8 2.0 2.7 2.9 10.0 3.7 5.2 6.0 28.4 3.3 3.0 2.5 76.7 3.7 8.0 11.7 1.3 4.6 13.2 4.5 5.7 6.6 35.7 2.3 6.4 6.0 7.1 4.7 2.9 18.6 21.2 3.5 18.8 9.9 5.0 0.1 5.2 19.8 22.4 215.1 460.7 0.2 175.8 62.9 51.1 32.4 0.1 0.3 0.1 7.9 420.8 0.4 0.7 3.9 0.6 45.9 20.7 1.2 2.0 88.5 0.2 120.7 0.8 0.3 251.3 0.1 135.9 15.6 211.1 55.5 1.6 0.0 0.4 55.6 0.0 1.5 0.2 4.0 0.2 7.1 0.1 17.0 0.2 5.9 0.5 0.2 12.9 0.0 2.2 0.1 15.3 0.2 1.4 106.8 206.9 6.2 305.8 37.6 1.2 1.0 0.0 138.9 0.3 13.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.4 5.4 2.8 2.8 0.8 2.0 5.2 6.0 3.7 2.3 4.7 5.0 50.0 0.0 1.3 34.9 0.4 25.6 0.8 1.5 0.6 6.1 1.3 3.4 14.2 0.0 5.8 12.9 0.0 132.4 0.4 0.0 0.0 0.2 8.7 4.2 105.2 36.1 0.0 5.5 82.3 0.6 40.8 388.5 3.1 2.0 1.3 22.5 34.6 0.6 15.3 0.0 123.5 0.0 0.0 0.8 39.0 22.8 236.1 5.7 42.7 30.0 2.3 0.8 0.0 76.9 218.7 1.7 0.0 227.2 1.7 0.7 0.1 0.6 3.3 0.2 26.3 139.5 55.8 3.3 3.4 0.8 20.6 65.8 4.3 51.3 0.0 0.2 FBXO45 Fbx45 ENSG00000174013 "F-box protein 45" P0C2W1 3 196568611-196589059 "Predicted intracellular proteins" "Neurogenesis, Ubl conjugation pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040730 Uncertain Approved Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA040730: AB_10959311" "unprognostic (7.17e-3)" "unprognostic (1.14e-1)" "unprognostic (8.37e-2)" "unprognostic (1.01e-2)" "unprognostic (8.14e-2)" "unprognostic (2.89e-1)" "prognostic unfavorable (7.61e-5)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.13e-2)" "unprognostic (9.48e-3)" "unprognostic (1.20e-3)" "prognostic unfavorable (1.16e-5)" "prognostic unfavorable (4.93e-5)" "unprognostic (5.18e-2)" "unprognostic (1.66e-1)" "unprognostic (6.93e-2)" "unprognostic (1.65e-1)" 5.1 4.2 10.7 6.1 11.5 13.9 7.3 11.8 14.8 4.5 6.8 6.9 5.3 4.7 3.0 8.9 3.6 4.4 3.6 11.0 10.9 3.7 6.9 4.5 6.7 10.7 10.9 5.0 4.6 7.2 3.1 5.4 10.4 5.1 7.0 8.2 4.0 4.3 13.8 12.7 5.1 5.0 11.6 5.1 5.5 12.2 11.5 8.8 3.7 11.5 10.0 6.8 5.0 11.7 45.5 8.5 17.6 22.4 11.6 11.4 20.9 19.7 9.0 15.3 15.6 23.9 15.1 19.1 33.1 12.8 22.8 19.0 33.9 22.5 28.1 27.7 15.3 34.8 15.5 15.1 11.1 46.9 17.1 5.8 24.9 17.3 31.8 8.0 16.9 30.5 42.4 39.2 17.2 45.3 27.5 21.9 27.4 40.3 32.5 23.1 23.0 46.2 12.9 18.3 35.6 24.4 21.4 36.8 23.5 15.4 63.3 31.1 16.8 17.7 19.1 25.7 53.8 38.3 68.5 52.6 15.4 59.6 17.3 1.3 0.9 1.1 0.8 0.9 1.4 0.5 0.8 0.5 1.2 0.8 0.8 0.9 0.4 0.6 1.1 1.4 1.6 0.4 10.7 11.5 11.8 14.8 11.0 10.9 10.7 10.9 10.4 11.6 11.5 11.7 10.2 12.8 4.1 6.5 6.6 9.8 10.2 5.6 4.6 20.1 10.5 7.7 10.8 4.3 4.2 3.7 14.6 2.6 11.5 7.9 0.0 4.4 15.5 8.0 12.9 8.0 17.4 6.1 13.8 7.7 4.6 7.8 10.7 8.8 1.3 6.9 7.9 9.9 5.8 13.5 15.0 8.2 4.1 9.1 11.0 18.9 5.6 7.6 5.4 8.4 8.3 9.3 4.1 6.6 12.4 8.3 4.8 6.4 8.0 14.8 4.0 3.4 6.8 10.7 0.0 10.5 7.5 32.4 24.4 9.4 13.5 1.9 8.2 7.1 9.8 14.5 FBXW8 "FBW6, FBW8, FBX29, FBXO29" ENSG00000174989 "F-box and WD repeat domain containing 8" Q8N3Y1 12 116910950-117031148 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 53.5;Excitatory neurons: 40.6;Inhibitory neurons: 38.9;Late spermatids: 84.1;Oligodendrocyte precursor cells: 38.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038850, HPA038851" Supported Supported Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 34: Spermatids - Unknown function" Cytosol "HPA038850: AB_2676238, HPA038851: AB_10673479" "unprognostic (2.63e-2)" "unprognostic (1.13e-1)" "unprognostic (9.03e-2)" "unprognostic (1.48e-2)" "unprognostic (1.08e-1)" "unprognostic (9.97e-2)" "unprognostic (3.35e-2)" "unprognostic (2.17e-1)" "unprognostic (2.39e-2)" "unprognostic (4.30e-2)" "unprognostic (1.32e-1)" "unprognostic (8.02e-2)" "unprognostic (2.28e-1)" "unprognostic (1.34e-1)" "unprognostic (6.20e-2)" "unprognostic (6.34e-2)" "unprognostic (2.55e-1)" 5.3 4.9 2.5 4.7 9.5 3.5 5.9 1.5 3.0 5.8 10.1 4.9 3.6 6.5 3.9 5.3 6.3 4.1 4.7 4.1 3.0 4.0 4.0 4.5 5.6 2.9 2.3 8.6 7.1 8.5 8.2 7.6 1.9 4.8 4.9 4.4 6.6 5.2 5.3 5.8 4.3 5.8 1.3 4.1 5.9 4.9 3.7 5.5 9.4 3.4 6.6 5.2 5.0 2.6 8.6 15.5 13.4 10.8 12.1 16.9 8.8 16.0 16.6 11.8 11.4 4.9 5.9 13.0 5.9 21.1 6.3 9.1 10.1 6.3 9.5 20.6 7.3 6.3 7.1 5.0 20.7 8.1 4.7 17.6 5.4 11.0 24.7 16.7 13.2 11.7 8.2 6.0 10.7 22.3 6.4 5.5 15.7 3.9 9.4 10.0 6.1 11.2 9.5 14.6 12.0 33.4 11.5 4.1 7.9 11.3 15.2 7.1 16.7 10.4 4.3 10.8 5.0 19.0 12.6 12.2 14.2 4.9 17.2 0.2 0.8 2.0 1.4 0.8 1.3 2.4 0.8 0.9 1.1 1.9 0.5 0.8 0.0 3.9 1.0 1.1 1.2 0.7 2.5 9.5 1.5 3.0 4.1 3.0 2.9 2.3 1.9 1.3 3.7 2.6 3.2 0.0 6.4 21.9 5.4 1.9 3.0 1.4 5.2 9.1 3.5 4.2 3.1 4.3 5.6 1.8 25.0 9.4 5.5 1.4 1.9 4.2 53.5 4.1 6.6 3.6 9.1 3.8 40.6 4.5 6.5 5.4 8.6 3.6 2.5 11.1 0.7 3.0 4.3 1.7 38.9 4.2 0.0 3.5 0.8 84.1 9.3 2.6 0.0 33.7 2.3 3.1 5.2 38.2 28.3 2.4 3.3 5.3 7.7 5.4 1.0 2.2 4.7 15.2 0.0 7.2 4.2 4.6 6.7 3.5 1.4 6.7 4.5 11.6 3.7 3.2 FBXW9 "Fbw9, MEC-15, MGC10870" ENSG00000132004 "F-box and WD repeat domain containing 9" Q5XUX1 19 12688053-12696631 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 65.6;Respiratory ciliated cells: 80.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042087 Approved Approved Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA042087: AB_10794168" "unprognostic (4.46e-1)" "unprognostic (4.31e-2)" "unprognostic (1.20e-2)" "unprognostic (1.65e-1)" "unprognostic (1.03e-1)" "unprognostic (2.82e-3)" "unprognostic (4.69e-3)" "unprognostic (4.91e-2)" "unprognostic (2.97e-2)" "unprognostic (1.07e-1)" "unprognostic (5.83e-2)" "unprognostic (2.71e-2)" "unprognostic (4.02e-2)" "unprognostic (6.08e-3)" "unprognostic (8.04e-2)" "unprognostic (2.61e-1)" "unprognostic (8.42e-3)" 4.2 7.9 4.4 2.1 4.4 4.2 5.6 2.9 5.8 5.2 9.0 5.2 4.4 4.9 2.0 10.3 13.1 2.9 2.9 4.7 4.3 8.6 5.1 4.5 3.0 4.1 6.3 4.0 7.3 4.3 7.4 2.6 4.2 7.2 1.7 2.0 7.6 3.5 2.7 9.4 4.0 1.7 4.0 3.9 5.6 14.9 4.4 2.9 7.5 0.8 1.9 4.6 5.8 3.2 16.6 11.1 7.2 10.6 3.1 5.2 8.7 5.3 5.4 11.1 9.1 6.2 10.0 4.1 13.5 4.8 2.7 14.7 6.9 10.0 1.9 2.9 18.5 4.9 13.2 10.4 7.0 12.3 2.9 7.0 15.8 7.7 3.8 6.6 8.8 9.4 11.9 2.7 2.5 34.5 13.4 16.1 12.2 8.8 10.4 7.0 5.0 23.2 10.0 4.9 16.5 19.6 7.9 16.5 7.6 2.3 16.5 9.3 4.3 6.5 6.0 8.1 8.5 16.4 7.3 4.5 8.1 4.5 4.3 0.0 7.4 0.0 2.7 7.1 4.6 2.8 2.9 2.1 11.1 2.5 2.8 2.0 0.3 4.7 4.9 3.1 5.7 5.0 4.4 4.4 2.9 5.8 4.7 4.3 4.1 6.3 4.2 4.0 4.4 3.2 4.8 3.2 5.4 1.3 1.3 6.0 5.2 18.6 8.0 2.0 12.1 13.0 0.7 8.6 14.3 1.8 6.2 14.4 1.5 5.7 5.9 18.1 6.4 65.6 6.9 4.2 4.8 11.8 3.7 16.0 8.4 4.4 5.6 6.8 0.0 10.7 4.6 3.6 7.0 0.0 3.1 9.2 22.4 4.5 3.7 8.5 2.5 5.9 3.6 0.0 4.2 4.9 1.0 1.0 1.2 11.6 5.6 4.5 1.7 4.2 5.5 17.4 80.3 7.1 6.6 4.4 6.5 30.8 17.3 9.2 8.2 6.4 2.4 20.3 12.5 4.9 FCRLB "FCRL2, FCRLM2, FCRLY, FLJ31052, FREB-2" ENSG00000162746 "Fc receptor like B" Q6BAA4 1 161721563-161728143 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.8" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 7.5;NK-cells: 11.3;Proximal tubular cells: 14.7" "Cancer enhanced" "Detected in many" "urothelial cancer: 7.8" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 6.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ hTERT+: 4.8;Daudi: 6.0;fHDF/TERT166: 8.8;HMC-1: 7.4;PC-3: 4.4" "Not detected" "Not detected" "Not detected" "Not detected" CAB026139 Uncertain Supported Cytosol "Intracellular and membrane" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "CAB026139: " "unprognostic (1.87e-1)" "unprognostic (1.20e-4)" "unprognostic (5.77e-3)" "unprognostic (7.49e-3)" "unprognostic (1.73e-3)" "unprognostic (2.95e-1)" "unprognostic (2.98e-2)" "unprognostic (1.18e-3)" "unprognostic (1.89e-1)" "unprognostic (3.59e-2)" "unprognostic (1.39e-1)" "unprognostic (1.60e-1)" "unprognostic (1.22e-2)" "unprognostic (2.25e-3)" "unprognostic (1.27e-1)" "unprognostic (9.92e-3)" "unprognostic (3.14e-2)" 0.2 0.1 0.5 0.7 0.4 0.0 0.1 0.5 0.7 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.5 0.4 0.7 0.3 0.1 0.9 0.5 0.5 0.1 0.2 0.1 0.0 0.1 0.6 0.1 0.1 0.1 0.3 0.9 0.0 0.2 0.1 0.0 0.4 0.3 0.1 0.1 0.4 0.0 0.1 0.0 1.8 0.2 0.1 0.6 0.6 0.1 0.0 0.3 0.4 0.6 0.0 3.7 4.8 1.2 1.2 0.1 0.1 6.0 0.2 8.8 0.2 0.0 0.2 0.3 3.1 0.1 0.3 0.2 0.1 0.1 0.2 0.0 7.4 1.1 0.0 2.1 0.1 0.3 1.1 0.0 0.3 0.3 0.1 0.3 0.0 2.1 0.1 0.0 4.4 0.0 0.4 0.2 0.1 0.2 0.0 0.0 0.0 0.1 1.9 0.2 0.0 0.0 0.6 1.3 0.6 1.3 0.7 0.0 0.0 2.3 2.5 0.4 0.6 6.4 0.1 1.8 1.8 0.0 0.6 3.4 1.1 1.0 0.4 4.7 0.5 0.8 1.0 3.7 0.2 0.0 0.0 0.5 0.5 0.4 0.5 0.7 0.5 0.4 0.5 0.5 0.6 0.4 0.4 0.6 2.8 0.0 0.0 0.3 2.9 1.1 1.1 1.0 0.6 0.2 1.5 1.5 1.5 0.0 1.2 3.7 0.0 2.1 3.9 0.1 5.9 1.3 0.1 0.3 1.3 2.3 1.2 5.3 0.9 1.1 5.6 1.1 0.0 0.4 0.0 1.2 7.5 1.2 1.4 0.0 1.2 0.0 0.0 1.9 1.2 0.2 0.0 3.4 1.8 0.0 0.7 3.4 11.3 0.0 0.3 1.0 0.1 0.4 3.0 0.6 0.0 14.7 0.7 0.7 0.0 0.2 1.6 2.7 1.4 1.3 0.4 0.8 2.4 2.2 0.0 1.1 FER "PPP1R74, TYK3" ENSG00000151422 "FER tyrosine kinase" P16591 5 108747841-109196841 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in all" 6 "Alveolar cells type 1: 80.1;Astrocytes: 207.3;Early spermatids: 158.1;Excitatory neurons: 266.3;granulocytes: 95.5;Inhibitory neurons: 313.8;Late spermatids: 182.4;Microglial cells: 227.7;Oligodendrocyte precursor cells: 284.0;Oligodendrocytes: 216.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 5 "RPMI-8226: 91.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007641, CAB022464" Approved Supported Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 25: RPMI-8226 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "CAB022464: , HPA007641: AB_1078845" "unprognostic (1.72e-1)" "unprognostic (1.66e-2)" "unprognostic (1.74e-1)" "unprognostic (2.46e-3)" "unprognostic (4.72e-2)" "unprognostic (5.65e-2)" "unprognostic (6.81e-2)" "unprognostic (7.39e-2)" "unprognostic (1.05e-1)" "unprognostic (8.36e-3)" "unprognostic (7.36e-2)" "unprognostic (8.05e-2)" "prognostic favorable (5.55e-4)" "unprognostic (3.83e-3)" "unprognostic (3.22e-1)" "unprognostic (1.03e-1)" "unprognostic (3.99e-3)" 4.2 3.7 3.4 3.0 3.2 1.6 3.6 2.8 3.4 3.8 0.6 3.9 1.7 3.7 2.9 4.2 3.0 3.3 3.0 3.1 3.9 3.5 2.3 3.7 1.4 3.6 3.7 4.6 1.9 9.4 2.5 4.2 3.8 3.0 2.4 5.7 2.5 3.9 1.3 4.5 2.0 4.9 4.1 2.7 2.2 6.7 3.1 2.8 6.4 2.0 2.0 3.5 3.2 5.0 9.8 3.4 11.0 18.0 6.6 10.1 7.2 11.4 11.0 6.5 7.6 19.0 5.5 15.3 6.9 13.8 8.4 6.3 6.2 14.4 14.7 6.5 8.4 9.8 14.5 7.0 4.4 5.6 8.2 6.2 7.9 15.8 17.5 6.4 9.8 14.6 12.9 11.1 8.4 2.7 4.4 1.7 1.6 0.9 7.0 3.3 10.7 91.7 6.4 3.3 3.8 5.6 18.6 1.0 11.4 7.0 4.4 2.4 14.7 12.5 10.2 6.5 9.0 9.4 14.9 5.9 7.4 1.9 6.0 8.9 3.7 4.6 1.2 2.5 2.1 10.3 0.7 1.4 2.3 3.4 1.2 1.5 0.3 1.1 2.0 4.5 1.7 0.9 3.4 3.2 2.8 3.4 3.1 3.9 3.6 3.7 3.8 4.1 3.1 5.0 23.8 80.1 28.3 207.3 9.5 29.2 15.8 9.5 25.6 17.6 6.6 8.5 21.9 10.0 21.8 14.7 18.8 3.9 7.5 4.9 1.9 13.6 158.1 13.1 17.2 19.7 8.4 10.7 266.3 6.0 10.7 31.4 16.8 12.6 95.5 21.8 18.9 2.3 8.2 18.5 313.8 4.5 8.2 9.5 13.4 182.4 19.3 14.1 14.2 227.7 12.0 10.5 4.1 284.0 216.0 9.1 4.7 17.7 13.7 12.1 1.7 6.9 27.9 16.3 6.6 30.7 23.8 7.7 11.5 13.2 17.6 3.1 10.4 10.2 4.1 6.9 FGF13 "FGF2, FHF2, FLJ30672, LINC00889" ENSG00000129682 "Fibroblast growth factor 13" Q92913 X 138614727-139222777 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 50.0;parathyroid gland: 49.5;skeletal muscle: 67.3;tongue: 52.3" "Cell type enriched" "Detected in many" 6 "Inhibitory neurons: 432.5" "Cancer enhanced" "Detected in some" "prostate cancer: 2.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.7" "Lineage enriched" "Detected in single" 9 "granulocytes: 3.7" "Cell line enhanced" "Detected in many" "AF22: 43.0;fHDF/TERT166: 38.1;HAP1: 39.8;RPMI-8226: 34.4;U-2197: 69.3;WM-115: 37.5" "Low region specificity" "Detected in all" HPA002809 Supported Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA002809: AB_1078855" "unprognostic (3.23e-1)" "unprognostic (3.13e-2)" "unprognostic (5.42e-2)" "unprognostic (1.42e-2)" "unprognostic (1.87e-1)" "unprognostic (2.87e-3)" "unprognostic (9.92e-3)" "unprognostic (2.97e-3)" "unprognostic (4.92e-2)" "unprognostic (5.90e-3)" "unprognostic (5.22e-3)" "unprognostic (6.79e-2)" "unprognostic (4.96e-4)" "unprognostic (4.36e-3)" "unprognostic (1.22e-1)" "unprognostic (2.27e-1)" "unprognostic (7.48e-2)" 18.5 2.6 17.8 2.9 18.9 4.1 6.6 4.0 30.2 11.3 4.9 7.0 4.0 10.7 3.4 6.6 3.6 6.1 1.9 39.4 20.7 7.4 1.8 2.3 5.3 12.4 15.2 8.8 1.1 49.5 4.2 13.3 50.0 17.6 4.8 11.3 11.2 4.9 67.3 1.8 4.7 6.6 11.3 6.2 5.3 4.1 21.9 0.9 5.2 52.3 2.2 6.0 4.3 14.6 0.1 0.5 43.0 0.1 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.2 0.3 0.7 38.1 0.3 2.7 39.8 0.1 0.0 0.3 11.1 0.2 0.3 1.6 1.5 0.3 0.5 0.6 1.0 0.1 0.0 0.2 0.0 2.5 1.8 12.4 4.4 0.3 0.1 0.3 4.4 0.1 14.3 6.6 2.8 34.4 6.3 0.2 0.1 0.2 0.0 0.3 26.8 21.0 0.1 0.2 0.8 1.3 1.8 69.3 19.1 16.2 9.8 0.1 15.3 12.8 37.5 1.6 0.2 0.8 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 3.7 0.1 0.2 0.4 0.1 0.0 17.8 18.9 4.0 30.2 39.4 20.7 12.4 15.2 50.0 11.3 21.9 14.6 9.7 0.0 0.0 12.7 0.1 0.4 3.0 0.3 2.8 3.6 18.3 4.1 2.6 10.0 3.0 7.3 0.0 0.2 0.0 0.5 17.6 4.2 0.0 7.7 5.0 3.6 2.4 0.0 43.5 5.8 0.3 6.1 3.1 20.5 0.0 1.4 1.4 0.1 29.3 0.0 432.5 0.8 6.1 3.7 1.4 1.4 26.1 0.6 1.8 62.8 0.6 44.8 0.0 14.1 2.4 3.8 6.7 24.5 0.1 16.9 0.0 2.9 1.8 4.2 32.9 18.0 13.7 0.0 3.7 0.1 0.9 0.1 0.3 0.8 0.3 1.0 FHOD1 FHOS ENSG00000135723 "Formin homology 2 domain containing 1" Q9Y613 16 67229387-67247481 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 88.1;skeletal muscle: 127.0" "Cell type enhanced" "Detected in many" "granulocytes: 40.6;Theca cells: 40.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HMC-1: 112.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA024468 Approved Supported Cytosol NA NA 1300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Cytosol "HPA024468: AB_1848568" "unprognostic (6.53e-3)" "prognostic unfavorable (9.57e-4)" "unprognostic (5.42e-2)" "unprognostic (2.14e-3)" "unprognostic (1.11e-1)" "unprognostic (2.18e-2)" "unprognostic (1.62e-1)" "unprognostic (1.81e-1)" "unprognostic (2.03e-1)" "unprognostic (1.50e-1)" "unprognostic (4.62e-2)" "unprognostic (4.27e-2)" "prognostic unfavorable (1.90e-8)" "unprognostic (1.72e-1)" "unprognostic (1.56e-1)" "unprognostic (3.14e-3)" "unprognostic (4.70e-2)" 16.9 16.9 3.6 9.6 3.5 6.2 13.2 3.5 4.0 9.6 4.6 9.3 5.9 8.5 1.6 4.5 7.9 5.5 10.4 3.4 3.3 10.5 3.3 26.6 8.5 4.1 4.0 14.7 7.7 3.7 5.4 8.9 3.9 8.8 4.2 0.3 8.4 3.9 127.0 6.2 9.7 5.8 4.0 88.1 7.2 5.0 4.8 4.1 16.8 29.8 5.9 7.4 6.7 3.8 12.0 31.6 11.8 9.8 46.1 27.9 39.2 24.9 19.8 27.2 26.3 22.3 15.7 14.1 17.5 18.0 8.8 14.7 13.5 20.0 13.5 11.3 21.7 63.1 13.9 24.5 12.2 26.3 112.1 34.8 2.6 42.2 4.1 24.3 43.0 19.9 32.9 9.3 17.6 41.0 18.1 48.3 17.6 11.0 10.0 20.3 25.9 33.8 8.7 4.9 3.7 19.2 38.2 22.4 22.5 11.7 23.8 21.1 51.6 37.4 22.0 24.0 20.3 29.9 32.0 20.7 76.1 24.7 34.7 0.3 0.7 0.1 0.2 0.2 0.3 0.0 0.3 0.2 0.4 0.1 0.1 0.1 0.5 0.3 0.2 0.2 0.3 0.6 3.6 3.5 3.5 4.0 3.4 3.3 4.1 4.0 3.9 4.0 4.8 3.8 18.0 12.8 21.6 4.6 7.2 5.7 1.8 2.0 3.4 1.8 11.5 8.0 13.8 10.0 5.9 5.5 8.4 8.7 11.4 16.9 0.0 3.6 1.1 3.5 8.1 22.3 9.1 8.6 2.5 5.9 4.7 10.9 5.6 4.7 40.6 12.0 25.0 0.8 17.1 1.7 2.2 13.1 2.0 20.3 19.7 1.1 10.5 19.8 3.6 17.8 18.9 2.9 10.3 2.0 0.6 7.4 6.1 10.9 7.1 3.1 6.3 1.4 3.9 1.2 26.3 4.2 15.7 19.0 12.3 5.6 3.7 1.9 13.3 40.3 13.8 1.7 FKBP3 "FKBP-25, FKBP25" ENSG00000100442 "FKBP prolyl isomerase 3" Q00688 14 45115599-45135319 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 424.4;tongue: 372.0" "Cell type enhanced" "Detected in all" "Late spermatids: 377.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000864, CAB012232, CAB012520" Supported Supported Cytosol NA NA 1300000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 80: Striated muscle - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB012232: , CAB012520: AB_873554, HPA000864: AB_1078873" "unprognostic (7.77e-2)" "unprognostic (1.47e-1)" "unprognostic (3.18e-1)" "unprognostic (9.72e-2)" "unprognostic (1.25e-1)" "unprognostic (9.82e-3)" "unprognostic (3.58e-3)" "unprognostic (2.28e-1)" "unprognostic (5.04e-3)" "unprognostic (1.22e-3)" "unprognostic (7.47e-2)" "unprognostic (6.92e-3)" "unprognostic (1.00e-1)" "unprognostic (3.07e-1)" "unprognostic (1.51e-1)" "unprognostic (1.00e-2)" "unprognostic (1.47e-1)" 40.9 46.8 100.3 35.8 102.3 38.4 50.0 110.1 122.1 38.1 91.8 49.4 44.7 31.4 64.8 54.7 31.4 29.8 109.5 101.9 100.6 66.5 69.7 27.6 53.7 100.7 99.3 35.3 32.8 55.5 56.6 46.9 100.1 57.7 49.1 82.3 37.1 37.9 424.4 38.3 47.8 39.2 99.8 39.9 38.0 52.9 101.4 59.6 40.1 372.0 57.7 43.3 38.6 105.8 161.0 175.3 249.0 132.4 109.0 117.8 98.3 96.2 110.3 149.3 163.5 154.8 134.1 85.1 98.9 110.0 84.1 130.0 188.4 124.8 211.7 123.7 111.0 69.8 138.8 202.6 107.1 122.2 72.8 112.0 127.5 87.2 80.1 136.8 198.0 131.9 102.9 62.1 179.9 196.9 197.5 163.0 126.7 178.3 164.5 187.0 183.7 102.9 242.2 183.7 151.2 59.2 154.8 94.5 156.0 186.4 222.6 89.9 128.7 113.0 195.6 59.9 75.1 104.0 198.8 132.5 68.3 83.0 108.1 23.4 22.4 22.1 18.7 27.3 22.8 29.7 25.0 25.7 33.3 21.8 23.4 26.7 3.6 24.2 29.4 43.0 30.8 20.2 100.3 102.3 110.1 122.1 101.9 100.6 100.7 99.3 100.1 99.8 101.4 105.8 48.3 41.7 46.6 25.8 45.3 47.8 94.4 205.5 45.5 79.3 39.9 46.7 202.5 48.6 101.4 93.8 10.4 320.9 51.2 56.4 252.4 131.1 212.7 55.0 83.3 58.5 56.1 50.9 49.7 73.0 135.4 70.0 36.7 68.1 53.7 75.6 38.2 91.1 131.1 40.4 44.5 71.2 124.1 39.9 43.0 377.4 80.8 53.7 69.4 17.8 110.7 80.7 50.4 21.1 34.3 88.4 53.7 97.8 58.0 76.4 91.8 220.1 73.5 67.4 105.2 71.3 118.5 154.0 111.2 65.0 47.9 165.0 48.8 84.1 96.1 77.6 FKBP6 "FKBP36, PPIase" ENSG00000077800 "FKBP prolyl isomerase 6" O75344 7 73328161-73358637 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 222 "testis: 58.5" "Group enriched" "Detected in some" 6 "Early spermatids: 68.5;Late spermatids: 92.4;Spermatocytes: 142.0;Spermatogonia: 37.2" "Cancer enriched" "Detected in single" 9 "testis cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA061109, HPA077010" Enhanced Approved Cytosol NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol "HPA061109: AB_2684430, HPA077010: " "unprognostic (5.07e-2)" "unprognostic (3.34e-2)" "unprognostic (1.56e-1)" "unprognostic (1.91e-1)" "unprognostic (1.05e-1)" "unprognostic (3.98e-2)" "unprognostic (8.72e-3)" "unprognostic (4.34e-2)" "unprognostic (1.51e-1)" "unprognostic (3.60e-1)" "unprognostic (4.29e-2)" "unprognostic (1.48e-1)" "unprognostic (6.20e-2)" "unprognostic (9.15e-2)" "unprognostic (2.47e-1)" "unprognostic (6.86e-2)" 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 58.5 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.2 0.0 0.5 0.0 0.0 0.1 0.2 0.6 0.0 0.6 0.0 0.3 0.5 1.5 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.2 68.5 5.2 0.3 0.2 0.0 0.0 0.3 0.2 0.0 0.2 0.0 1.0 0.0 0.2 0.4 0.2 0.3 0.0 0.3 0.0 2.0 1.3 0.0 92.4 3.1 0.3 0.0 0.0 0.0 0.5 0.0 0.0 1.1 0.2 0.0 1.2 0.0 0.0 0.0 0.1 12.6 0.5 0.0 0.3 0.1 142.0 37.2 0.0 0.0 0.1 0.1 0.0 0.0 0.2 FMNL1 "C17orf1, C17orf1B, FMNL" ENSG00000184922 "Formin like 1" O95466 17 45221444-45247319 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 277.6;lymphoid tissue: 104.9" "Cell type enhanced" "Detected in many" "B-cells: 108.1;dendritic cells: 160.0;Kupffer cells: 77.4;Langerhans cells: 141.6;Macrophages: 115.5;monocytes: 132.8;NK-cells: 152.4;Plasma cells: 109.8;T-cells: 134.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 190.8;MOLT-4: 138.4;U-266/70: 158.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008129, HPA028288" Enhanced Approved Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA008129: AB_1848963, HPA028288: AB_10612110" "unprognostic (1.90e-2)" "unprognostic (1.37e-1)" "unprognostic (2.07e-2)" "unprognostic (8.60e-2)" "unprognostic (1.95e-2)" "unprognostic (1.24e-2)" "unprognostic (2.01e-1)" "unprognostic (1.58e-1)" "unprognostic (5.44e-2)" "unprognostic (6.06e-2)" "unprognostic (2.37e-1)" "unprognostic (4.07e-1)" "prognostic unfavorable (4.23e-8)" "unprognostic (1.29e-1)" "unprognostic (3.01e-2)" "unprognostic (3.46e-2)" "unprognostic (2.16e-1)" 22.9 7.4 14.2 68.5 11.3 277.6 13.4 10.1 21.5 10.4 9.0 12.5 11.5 5.6 2.3 8.9 14.1 18.5 12.7 20.8 9.0 8.4 8.5 54.6 69.4 16.2 11.2 3.4 6.5 6.8 16.3 12.2 15.5 10.4 7.3 1.3 16.2 3.3 4.7 9.5 36.7 8.2 11.1 104.9 13.7 4.2 17.2 49.7 9.0 6.2 38.7 21.4 10.5 16.3 16.9 32.2 0.3 1.7 0.3 7.0 1.7 2.0 4.3 11.8 8.8 1.5 7.2 51.4 16.2 0.6 12.4 2.7 0.0 0.4 3.9 91.1 4.4 29.8 51.0 2.7 32.6 78.6 100.6 5.4 1.4 15.6 6.7 16.4 0.3 55.8 2.7 190.8 8.8 10.9 138.4 80.7 1.6 2.1 1.0 86.2 11.3 92.7 3.3 2.1 10.0 4.8 9.9 1.7 4.0 2.6 9.2 62.7 4.0 0.7 11.1 1.9 73.3 158.9 75.7 52.2 1.4 62.8 2.5 11.1 6.5 11.3 8.6 7.4 5.7 4.5 6.6 9.4 5.6 5.1 4.4 5.8 28.4 7.2 5.9 3.3 8.1 5.3 14.2 11.3 10.1 21.5 20.8 9.0 16.2 11.2 15.5 11.1 17.2 16.3 7.2 3.2 3.0 0.0 108.1 6.1 2.9 0.9 2.2 4.9 3.3 4.7 2.5 1.5 1.1 1.8 0.0 0.6 160.0 0.7 0.0 1.5 2.5 0.7 4.3 5.7 1.2 34.9 12.8 0.9 1.2 12.9 4.6 1.2 22.9 0.2 6.1 1.5 45.3 3.3 10.3 0.4 0.0 77.4 141.6 0.7 5.3 115.5 44.4 9.4 132.8 0.9 152.4 0.5 1.0 0.5 0.1 0.0 109.8 1.9 0.2 0.8 1.0 1.6 6.6 9.3 2.4 0.8 3.5 0.6 6.1 2.5 134.6 0.2 0.5 1.4 FMR1 "FMRP, FRAXA, MGC87458, POF, POF1" ENSG00000102081 "FMRP translational regulator 1" Q06787 X 147911919-147951125 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, Host-virus interaction, mRNA processing, mRNA splicing, mRNA transport, Neurogenesis, RNA-mediated gene silencing, Translation regulation, Transport" "Activator, Repressor, Ribonucleoprotein, RNA-binding" "Disease variant, Mental retardation, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012444, HPA050118, HPA056084" Approved Enhanced Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 44: Endometrium - Transcription" Cytosol "CAB012444: AB_732400, HPA050118: AB_2681023, HPA056084: AB_2683033" "unprognostic (4.11e-1)" "unprognostic (1.25e-3)" "unprognostic (1.89e-3)" "prognostic unfavorable (1.32e-4)" "unprognostic (4.58e-2)" "unprognostic (2.21e-1)" "unprognostic (1.23e-1)" "unprognostic (6.45e-3)" "unprognostic (2.59e-2)" "unprognostic (1.26e-2)" "unprognostic (2.29e-2)" "unprognostic (3.30e-2)" "unprognostic (3.15e-3)" "unprognostic (6.56e-2)" "unprognostic (2.24e-1)" "unprognostic (1.55e-1)" "unprognostic (5.98e-2)" 18.1 16.5 22.3 20.6 24.1 43.5 18.3 29.6 29.2 18.8 16.1 19.1 17.5 27.3 41.0 17.0 22.8 15.9 20.1 21.7 21.0 34.0 39.6 20.1 22.7 21.9 21.1 27.7 13.3 29.6 13.5 31.2 21.3 16.5 18.9 27.6 14.1 21.4 9.5 23.2 19.7 21.1 22.7 27.7 17.8 19.6 22.9 24.6 30.6 11.6 21.7 16.7 14.7 23.4 44.9 39.6 41.2 27.2 24.4 19.4 31.9 23.8 24.9 37.6 66.4 43.5 42.1 89.5 93.5 29.8 43.3 74.4 65.8 30.2 42.0 34.9 45.2 25.3 71.3 41.4 24.0 28.3 15.1 21.2 16.2 31.6 28.8 22.6 31.8 24.4 15.9 57.7 32.7 59.0 32.0 20.3 18.2 30.9 21.8 34.7 116.8 37.6 43.2 119.3 35.1 23.3 26.8 24.4 35.7 55.4 21.8 24.9 30.4 30.5 25.5 37.7 60.0 61.1 65.5 94.5 27.4 46.9 16.3 2.0 1.3 3.4 2.7 1.6 3.5 2.6 1.8 3.1 1.7 2.4 2.3 2.7 3.5 2.5 1.6 1.3 2.4 1.3 22.3 24.1 29.6 29.2 21.7 21.0 21.9 21.1 21.3 22.7 22.9 23.4 35.3 57.7 26.6 26.8 22.1 31.4 16.0 12.6 21.1 37.5 20.7 17.4 43.2 14.3 23.9 22.0 12.5 37.2 37.1 27.2 19.6 14.7 1.0 36.4 42.5 27.2 14.9 10.7 33.3 9.8 43.5 27.2 17.9 49.3 19.7 36.8 17.5 37.5 15.4 70.7 32.2 13.8 18.3 25.4 15.7 3.0 30.1 23.7 35.6 29.0 16.8 40.0 11.3 28.6 33.9 13.5 18.1 29.7 20.3 22.7 20.7 42.6 23.4 30.0 6.6 37.2 33.3 14.9 20.9 28.1 32.4 40.8 24.1 39.4 16.9 34.7 FNBP1L "C1orf39, FLJ20275, TOCA1" ENSG00000137942 "Formin binding protein 1 like" Q5T0N5 1 93448118-93554661 "Predicted intracellular proteins" "Autophagy, Endocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 7.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 7.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065273 Approved Supported Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 7: Kidney - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA065273: AB_2685452" "unprognostic (1.83e-1)" "unprognostic (4.28e-2)" "unprognostic (2.57e-3)" "unprognostic (8.46e-2)" "unprognostic (7.68e-2)" "unprognostic (8.65e-2)" "prognostic unfavorable (8.92e-4)" "unprognostic (5.89e-2)" "unprognostic (1.74e-1)" "unprognostic (6.35e-2)" "unprognostic (1.30e-1)" "unprognostic (1.37e-1)" "prognostic favorable (4.72e-7)" "unprognostic (3.59e-2)" "unprognostic (5.64e-2)" "unprognostic (2.74e-2)" "unprognostic (1.78e-1)" 28.3 7.8 13.6 5.4 25.8 2.1 33.0 13.6 13.8 18.0 13.8 17.3 20.6 16.8 18.6 8.9 13.4 14.5 20.0 12.0 15.4 36.1 13.3 16.8 3.1 14.6 19.1 13.9 17.3 20.8 10.5 17.2 14.2 15.6 17.5 12.4 43.1 11.5 17.4 12.7 20.2 12.3 15.9 2.8 23.7 15.0 14.4 6.5 31.8 21.4 4.0 14.9 13.2 12.7 29.7 16.2 83.4 46.8 17.6 12.4 92.8 14.6 9.9 10.8 15.0 19.9 9.2 0.1 29.4 14.3 29.0 14.9 20.3 16.7 15.4 18.5 15.2 15.8 23.5 29.9 8.8 2.8 0.3 23.0 27.2 10.2 14.8 28.2 52.1 18.1 6.2 0.1 25.8 13.8 11.6 1.2 63.7 50.5 16.4 24.4 63.7 7.8 47.5 44.6 32.6 47.0 45.4 88.0 25.8 97.3 33.5 4.0 52.1 25.2 31.7 0.6 10.2 9.1 7.5 0.2 2.5 0.4 17.5 7.3 0.1 0.7 0.0 0.0 0.0 0.3 0.3 0.0 0.3 0.4 0.0 0.2 0.0 0.0 0.0 1.5 0.2 0.1 13.6 25.8 13.6 13.8 12.0 15.4 14.6 19.1 14.2 15.9 14.4 12.7 130.0 109.0 42.1 48.0 4.3 26.5 61.5 27.5 18.2 13.3 62.9 59.1 42.6 40.0 60.9 62.5 4.2 37.6 2.2 35.4 56.7 77.9 12.1 61.1 30.0 49.8 67.0 36.6 41.0 48.4 35.7 20.5 50.0 91.7 16.4 19.6 25.0 21.0 11.8 69.0 110.8 33.0 14.2 4.7 22.7 19.7 8.1 10.6 39.2 80.6 7.1 18.8 0.0 55.3 4.2 55.8 34.5 3.8 1.0 56.0 43.6 50.8 53.8 10.0 26.3 5.9 49.9 23.4 37.2 22.0 25.7 17.1 4.1 10.2 38.4 75.6 FNDC8 DKFZp434H2215 ENSG00000073598 "Fibronectin type III domain containing 8" Q8TC99 17 35121615-35130732 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 474 "testis: 89.0" "Group enriched" "Detected in some" 73 "Early spermatids: 592.7;Late spermatids: 2294.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.3;JURKAT: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA026521, HPA059803" Supported Approved Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 36: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA026521: AB_2106163, HPA059803: " "unprognostic (1.45e-1)" "unprognostic (6.58e-2)" "unprognostic (2.32e-1)" "unprognostic (1.17e-1)" "unprognostic (1.25e-2)" "unprognostic (2.10e-1)" "unprognostic (5.88e-2)" "unprognostic (1.91e-1)" "unprognostic (2.02e-1)" "unprognostic (1.70e-1)" "unprognostic (8.43e-2)" "unprognostic (3.48e-3)" "unprognostic (9.02e-2)" "unprognostic (6.41e-3)" "unprognostic (1.09e-2)" "unprognostic (1.47e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 89.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.3 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.4 0.0 0.1 0.5 0.3 0.1 0.0 0.1 0.7 0.3 0.7 0.0 0.2 0.1 0.2 0.2 0.1 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.2 0.5 0.7 0.7 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 592.7 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2294.8 7.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.1 0.0 0.0 19.7 0.0 0.0 7.9 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FNTA "FPTA, PGGT1A, PTAR2" ENSG00000168522 "Farnesyltransferase, CAAX box, alpha" P49354 8 43034194-43085788 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Prenyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010149, HPA018830" Approved Approved Cytosol NA NA 170000 "Cluster 26: Non-specific - Mitochondria" "Cluster 70: Brain - Nervous system development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "CAB010149: AB_2106299, HPA018830: AB_1848992" "unprognostic (2.09e-1)" "unprognostic (1.35e-1)" "unprognostic (2.90e-1)" "unprognostic (1.86e-3)" "unprognostic (2.64e-1)" "unprognostic (4.70e-3)" "unprognostic (1.83e-2)" "unprognostic (3.69e-2)" "unprognostic (1.70e-2)" "unprognostic (5.37e-2)" "unprognostic (3.25e-2)" "unprognostic (4.10e-1)" "prognostic unfavorable (2.94e-12)" "unprognostic (3.63e-2)" "unprognostic (2.33e-1)" "unprognostic (3.19e-2)" "unprognostic (1.29e-3)" 53.6 33.4 57.7 26.3 69.3 26.8 46.1 74.0 74.0 41.3 52.7 46.3 35.9 34.0 43.2 45.4 33.4 27.1 48.1 54.2 63.7 37.4 47.2 34.7 45.5 75.1 64.8 33.0 43.9 34.3 36.6 50.0 73.6 38.3 32.5 33.8 36.5 34.1 74.3 51.0 32.9 31.4 73.2 36.7 35.4 26.9 61.9 39.9 31.6 64.7 44.2 40.9 43.1 87.6 78.8 37.5 50.9 16.7 88.6 112.5 43.4 44.9 52.4 50.1 46.3 62.1 56.9 88.5 35.5 54.1 67.6 41.9 63.1 71.5 59.4 26.2 42.2 70.9 25.5 54.2 112.7 30.4 35.8 87.6 119.0 36.3 104.2 74.4 89.4 47.9 86.1 50.4 58.5 9.9 72.3 47.1 91.3 66.4 27.1 63.1 83.0 47.8 70.5 58.4 29.7 47.4 56.6 47.3 78.9 59.1 59.1 55.3 69.9 17.9 22.1 68.6 48.0 47.7 46.2 89.2 43.0 56.4 41.3 3.1 7.7 14.3 9.5 10.7 11.3 14.1 9.7 12.6 13.3 15.2 12.9 12.9 4.3 16.1 7.8 12.6 14.3 6.4 57.7 69.3 74.0 74.0 54.2 63.7 75.1 64.8 73.6 73.2 61.9 87.6 68.7 57.7 20.3 33.0 57.4 87.7 82.3 55.3 58.1 22.5 35.5 34.8 44.9 34.3 41.2 33.1 37.5 135.6 69.1 29.6 70.5 73.0 41.2 40.7 55.1 55.8 32.2 38.9 27.9 70.1 124.4 58.7 28.5 46.2 32.4 58.6 56.0 25.9 80.5 20.2 31.9 39.6 34.6 47.5 60.7 52.8 48.1 49.2 94.3 33.7 75.7 42.8 69.0 25.6 79.8 69.4 41.2 60.2 40.8 109.3 67.0 54.8 46.7 57.5 52.6 56.2 47.2 65.9 37.1 73.9 95.6 207.6 60.4 69.6 49.1 76.6 FREM2 DKFZp686J0811 ENSG00000150893 "FRAS1 related extracellular matrix 2" Q5SZK8 13 38687077-38887131 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 7.7;thyroid gland: 4.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 27.2;Astrocytes: 46.0;Cholangiocytes: 15.7;Endometrial ciliated cells: 18.6;Glandular and luminal cells: 48.6;Oligodendrocyte precursor cells: 15.6;Proximal tubular cells: 24.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 15.5;HAP1: 10.6;MCF7: 7.8;RT4: 7.2;SK-BR-3: 6.3;SuSa: 29.7;WM-115: 5.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA028831 Uncertain Approved Cytosol NA NA 1500000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" Cytosol "HPA028831: AB_10603668" "unprognostic (1.71e-2)" "unprognostic (3.72e-1)" "unprognostic (1.92e-1)" "unprognostic (1.10e-1)" "unprognostic (4.69e-1)" "unprognostic (6.24e-2)" "unprognostic (1.62e-1)" "unprognostic (8.42e-3)" "unprognostic (8.54e-2)" "unprognostic (1.64e-3)" "unprognostic (4.25e-1)" "unprognostic (2.54e-1)" "prognostic favorable (2.23e-7)" "unprognostic (7.21e-2)" "unprognostic (1.40e-1)" "unprognostic (9.92e-2)" "unprognostic (3.14e-1)" 0.2 0.1 0.3 0.0 1.1 0.0 0.2 0.2 0.9 0.3 0.1 0.5 0.1 0.5 0.2 0.0 0.4 0.8 0.0 0.6 0.0 7.7 2.0 2.2 0.0 0.0 0.4 0.7 2.7 0.0 0.3 1.4 0.0 1.8 0.1 0.3 0.0 0.7 2.8 0.1 0.2 0.3 0.0 0.1 0.9 0.3 0.0 0.2 4.9 3.6 0.0 0.2 0.0 0.0 0.0 0.0 15.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.1 10.6 0.0 0.0 0.3 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 2.3 0.0 0.2 0.0 1.4 0.1 2.3 7.2 0.2 0.1 0.0 6.3 0.3 29.7 1.1 0.0 0.0 0.0 0.8 0.0 1.6 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.1 0.2 0.9 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.8 0.0 27.2 46.0 0.0 0.6 0.1 0.7 0.0 0.2 0.4 0.5 2.7 15.7 1.4 1.8 0.0 5.9 0.0 0.3 5.9 3.2 0.5 18.6 4.5 0.6 0.0 0.0 0.5 0.2 0.4 0.4 0.0 48.6 0.0 0.5 0.0 1.3 0.8 0.0 9.1 0.1 2.0 0.3 0.0 0.1 0.0 0.2 0.0 3.7 0.0 3.3 0.0 15.6 9.7 1.0 0.1 0.0 0.0 0.0 0.0 24.8 2.9 0.3 0.0 3.1 0.7 0.2 0.9 0.0 0.1 1.9 0.5 2.9 0.1 0.1 FSD2 "RP11-127F21, SPRYD1" ENSG00000186628 "Fibronectin type III and SPRY domain containing 2" A1L4K1 15 82755362-82806070 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 35 "heart muscle: 52.3;skeletal muscle: 154.3;tongue: 44.3" "Cell type enriched" "Detected in some" 6 "Cardiomyocytes: 81.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 3.6;U-266/70: 4.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA046263 Approved Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "HPA046263: AB_2679604" "unprognostic (2.80e-1)" "unprognostic (3.54e-1)" "unprognostic (6.63e-2)" "unprognostic (6.30e-2)" "unprognostic (7.71e-2)" "unprognostic (1.83e-1)" "unprognostic (5.97e-2)" "unprognostic (7.66e-2)" "unprognostic (1.07e-1)" "unprognostic (9.37e-2)" "unprognostic (3.05e-2)" "unprognostic (2.21e-1)" "unprognostic (1.07e-2)" "unprognostic (1.27e-1)" "unprognostic (8.03e-2)" "unprognostic (1.68e-2)" "unprognostic (1.59e-2)" 0.2 0.7 0.2 0.9 0.2 0.8 0.1 0.7 0.4 0.0 0.0 0.1 0.9 0.4 0.6 1.9 0.3 0.3 52.3 0.3 0.5 0.3 0.1 0.2 1.1 0.1 0.1 0.6 0.6 0.7 0.1 0.3 0.2 1.2 0.0 2.4 0.8 0.0 154.3 1.5 0.8 0.1 0.0 0.6 0.6 0.7 0.3 0.0 0.9 44.3 0.1 0.1 0.0 0.6 0.7 0.7 1.1 1.3 0.0 0.0 0.6 0.7 0.0 0.0 0.0 0.6 1.2 2.3 0.5 0.0 0.6 2.8 0.0 0.0 0.2 0.4 3.1 1.3 3.6 1.0 0.0 0.7 0.5 0.0 0.0 0.0 0.1 0.7 0.0 1.0 1.2 2.0 0.0 0.7 0.4 1.4 1.0 0.5 0.6 0.8 0.8 0.6 0.1 1.3 1.1 0.9 0.5 0.5 0.9 0.5 0.9 1.0 0.5 1.6 0.8 0.6 1.0 4.7 2.1 0.8 1.0 2.8 0.4 0.4 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.2 0.7 0.4 0.3 0.5 0.1 0.1 0.2 0.0 0.3 0.6 0.4 0.0 2.2 1.3 0.2 0.4 1.0 0.2 0.0 2.1 0.5 0.3 81.6 1.5 0.8 0.0 6.2 0.1 0.3 0.1 0.0 0.0 4.8 1.7 0.3 1.2 1.2 0.0 3.9 0.4 0.1 3.0 0.0 1.6 1.3 0.6 0.0 0.0 0.3 11.8 3.6 0.0 2.0 0.3 2.1 6.1 0.3 0.2 0.0 1.0 0.1 0.7 0.0 4.0 3.3 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.5 4.5 0.0 4.5 0.6 0.6 0.3 0.0 0.6 0.3 0.4 0.2 0.1 0.3 FTL "MGC71996, NBIA3" ENSG00000087086 "Ferritin light chain" P02792 19 48965309-48966879 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Iron storage" "Cancer-related genes, Cataract, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 14422.9" "Cell type enhanced" "Detected in all" "Hofbauer cells: 74983.4;Kupffer cells: 70127.1;Macrophages: 34584.5;Proximal tubular cells: 58047.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "granulocytes: 125209.0;monocytes: 102128.9" "Cell line enhanced" "Detected in all" "HHSteC: 24796.9;HSkMC: 20811.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020769, HPA041602" Enhanced Approved Cytosol NA NA 170000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB020769: , HPA041602: AB_2677575" "unprognostic (2.95e-1)" "unprognostic (2.64e-2)" "unprognostic (1.31e-1)" "unprognostic (1.56e-3)" "unprognostic (7.48e-2)" "unprognostic (5.28e-2)" "unprognostic (2.16e-3)" "unprognostic (6.17e-3)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (2.66e-1)" "unprognostic (2.96e-1)" "prognostic unfavorable (4.40e-5)" "unprognostic (1.32e-1)" "unprognostic (2.43e-2)" "unprognostic (2.30e-2)" "unprognostic (1.87e-2)" 6778.7 3262.2 6806.2 2353.2 7172.4 4213.8 4226.0 6782.1 10053.2 2094.3 6429.7 2451.1 2427.0 1523.4 1010.8 1306.2 2169.9 4298.0 2537.3 6497.7 6998.4 8845.6 14422.9 7261.1 3353.2 7250.8 6998.4 2455.3 2166.2 931.7 1730.4 3423.2 7218.5 1946.5 1800.0 684.9 1663.5 1390.4 1345.9 1449.7 2806.6 1842.3 7149.5 6751.4 3204.5 455.9 7581.8 1168.9 3000.4 1072.0 1334.6 4239.9 1804.7 7334.0 869.7 12906.5 949.6 1457.0 16013.9 16478.6 1693.1 2194.1 12820.0 3090.7 6903.8 2852.3 3413.2 656.4 4104.3 13203.9 6755.6 505.8 788.2 1301.8 2765.6 8895.0 507.6 1740.0 3222.8 18949.7 24796.9 4133.3 5591.2 20811.1 1735.9 5272.5 2301.6 4590.4 4549.8 774.6 3284.9 1328.2 6198.4 213.0 1152.1 2402.8 1729.8 15140.6 1306.9 947.6 643.0 6763.9 1989.7 545.0 1209.9 701.5 5761.7 313.4 1239.5 5104.1 183.2 8493.4 3438.3 3353.4 1740.1 4364.3 3083.1 5690.2 13742.1 625.1 3563.9 4334.7 6017.7 64938.4 71067.8 77353.0 6560.6 102128.9 7527.7 17097.3 7247.4 7054.3 25176.6 15607.2 8656.4 7466.9 125209.0 4978.3 91398.0 10579.6 9634.4 94147.5 6806.2 7172.4 6782.1 10053.2 6497.7 6998.4 7250.8 6998.4 7218.5 7149.5 7581.8 7334.0 2757.2 1125.0 3379.9 88.5 3311.5 2793.9 6799.5 2785.4 2159.8 474.7 2597.9 3977.3 777.8 4398.0 2550.4 2021.2 177.2 941.5 2199.4 2314.2 10704.0 4251.2 290.2 504.9 1413.1 4867.0 1613.4 4331.2 60.6 6134.8 1447.8 5703.3 1715.1 617.4 2365.7 942.2 4598.0 23702.0 74983.4 533.3 113.8 2368.8 3039.4 70127.1 16939.0 1601.8 4175.9 34584.5 5085.3 129.3 22965.8 3161.9 2020.6 55.8 309.7 6905.5 5604.7 2010.8 4884.7 9790.5 21474.5 58047.8 1908.0 682.6 1341.1 1643.8 3455.6 82.1 311.2 1985.5 2226.7 1502.7 2590.4 1492.0 2816.8 13083.6 FTSJ1 "CDLIV, JM23, MRX44, MRX9, SPB1, TRM7, TRMT7" ENSG00000068438 "FtsJ RNA 2'-O-methyltransferase 1" Q9UET6 X 48476021-48486364 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 75.7;Pancreatic endocrine cells: 60.1;Plasma cells: 59.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002718 Approved Approved Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "HPA002718: AB_1078914" "unprognostic (2.56e-2)" "unprognostic (1.24e-2)" "unprognostic (1.44e-1)" "unprognostic (3.37e-1)" "unprognostic (2.13e-1)" "unprognostic (6.77e-2)" "prognostic unfavorable (1.74e-5)" "unprognostic (1.95e-2)" "unprognostic (2.39e-1)" "unprognostic (3.96e-3)" "unprognostic (2.06e-3)" "unprognostic (7.82e-2)" "prognostic unfavorable (5.24e-10)" "unprognostic (2.61e-1)" "unprognostic (1.49e-1)" "unprognostic (1.56e-2)" "unprognostic (1.23e-1)" 14.6 15.2 5.7 14.5 6.8 16.0 13.8 6.5 9.0 16.0 5.2 10.2 8.2 13.8 4.6 14.9 12.1 8.6 11.4 6.6 6.7 10.1 9.8 13.3 16.2 6.0 6.2 12.7 16.8 12.4 12.2 8.4 6.2 10.3 7.7 5.7 15.4 12.8 14.8 14.2 10.2 12.3 6.2 13.7 13.7 9.8 5.8 14.8 14.3 10.9 13.4 14.3 14.1 6.6 75.9 51.1 19.1 76.4 27.1 27.9 31.3 36.0 34.3 51.4 40.5 30.8 102.6 43.6 26.3 55.4 32.4 49.8 38.3 127.3 23.1 33.4 36.3 27.8 62.5 35.5 75.8 38.5 67.4 26.0 63.0 64.8 63.2 28.5 36.4 49.2 24.1 35.2 67.4 42.6 50.4 27.3 43.2 32.1 86.6 40.4 62.7 91.2 48.3 25.4 26.0 25.5 57.4 31.1 27.5 22.1 35.7 21.7 35.8 40.6 54.9 85.3 44.9 47.6 39.8 31.4 89.6 71.3 43.6 19.5 23.7 19.1 34.6 27.1 43.0 27.2 29.5 35.4 28.3 31.5 26.8 34.5 3.4 30.3 27.8 19.1 30.2 27.8 5.7 6.8 6.5 9.0 6.6 6.7 6.0 6.2 6.2 6.2 5.8 6.6 15.1 6.4 11.0 3.9 20.6 12.7 11.4 30.7 14.2 4.5 8.5 8.8 6.7 4.3 23.8 7.3 2.1 5.3 19.7 6.6 17.6 21.2 49.5 11.1 11.8 13.4 5.4 14.7 4.4 18.2 28.7 12.4 16.3 15.2 8.8 9.2 6.4 5.9 17.0 3.3 4.3 11.3 10.2 8.4 10.6 75.7 10.8 11.0 5.4 5.6 8.9 5.7 19.6 3.0 5.8 60.1 2.7 8.6 59.5 17.0 4.8 11.3 14.0 6.5 13.1 9.6 16.7 7.5 10.1 15.0 10.9 5.7 17.0 10.7 9.4 26.5 FUZ "CPLANE3, FLJ22688, Fy" ENSG00000010361 "Fuzzy planar cell polarity protein" Q9BT04 19 49806866-49817376 "Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 78.7" "Group enriched" "Detected in many" 18 "Early spermatids: 1243.5;Late spermatids: 2329.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041779, HPA042196" Approved Approved Cytosol No NA "Cluster 5: Granulocytes - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA041779: AB_10793974, HPA042196: AB_10797383" "unprognostic (2.40e-3)" "unprognostic (1.31e-1)" "unprognostic (7.73e-2)" "unprognostic (2.13e-1)" "unprognostic (1.49e-2)" "unprognostic (1.18e-2)" "unprognostic (4.36e-3)" "unprognostic (9.67e-2)" "unprognostic (1.47e-1)" "unprognostic (1.97e-2)" "unprognostic (1.06e-2)" "unprognostic (1.80e-1)" "prognostic favorable (1.50e-5)" "unprognostic (1.26e-2)" "unprognostic (2.03e-1)" "unprognostic (1.54e-1)" "unprognostic (1.70e-1)" 9.3 17.6 17.3 2.8 21.0 6.2 9.3 18.8 20.8 11.2 19.7 12.1 4.2 11.1 7.3 6.8 19.5 5.2 13.6 16.4 16.8 16.8 7.1 7.7 4.6 19.9 19.1 15.4 12.3 7.1 12.5 4.0 18.2 11.2 1.9 4.9 7.5 7.3 20.4 6.6 6.9 4.1 19.5 8.8 10.2 78.7 18.7 6.0 11.5 12.4 2.2 9.0 8.2 20.4 0.1 10.6 9.5 12.2 8.9 9.5 2.7 5.2 5.4 7.9 11.0 0.9 17.2 3.1 10.6 4.9 2.5 4.3 2.7 9.2 3.5 11.7 20.5 13.0 7.6 0.0 10.1 7.6 7.0 10.1 6.3 16.1 4.0 6.2 7.5 18.6 3.0 8.7 4.1 0.5 14.1 15.4 15.7 8.4 6.3 24.4 7.7 7.4 9.7 2.7 26.5 31.0 1.0 10.8 17.9 3.7 6.2 4.7 3.7 6.6 5.9 1.9 1.9 24.9 26.5 8.4 7.6 0.2 8.4 7.0 4.6 17.7 4.9 2.2 4.1 5.3 3.1 4.2 3.8 6.0 3.8 4.3 10.6 3.8 1.6 15.0 3.8 2.6 17.3 21.0 18.8 20.8 16.4 16.8 19.9 19.1 18.2 19.5 18.7 20.4 9.2 0.0 2.8 6.2 8.4 3.8 19.3 10.1 8.6 7.2 14.5 14.6 3.9 17.2 7.3 7.3 4.2 17.5 12.2 1.9 66.5 15.3 1243.5 61.6 8.0 6.5 2.4 19.3 2.7 5.1 12.1 11.1 6.1 8.1 10.2 11.5 13.6 5.8 13.2 10.1 3.0 3.5 12.2 7.1 7.6 2329.6 27.7 6.7 0.0 2.8 7.9 26.1 5.2 2.0 9.9 4.5 6.1 17.7 10.9 8.0 7.3 86.1 35.4 11.3 0.0 17.1 9.9 95.3 13.5 5.0 4.1 12.0 6.4 13.7 5.5 14.1 FXR1 ENSG00000114416 "FMR1 autosomal homolog 1" P51114 3 180868141-180982753 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Myogenesis" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 788.7;tongue: 451.3" "Group enriched" "Detected in all" 4 "Early spermatids: 986.2;Late spermatids: 1759.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018246, HPA055475" Approved Enhanced Cytosol NA NA 15000 "Cluster 35: T-regs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA018246: AB_1849204, HPA055475: AB_2682828" "unprognostic (1.38e-1)" "unprognostic (1.59e-2)" "unprognostic (5.23e-2)" "prognostic unfavorable (5.96e-4)" "unprognostic (1.04e-2)" "unprognostic (1.90e-3)" "prognostic unfavorable (2.70e-4)" "unprognostic (7.77e-3)" "unprognostic (9.20e-2)" "unprognostic (2.75e-2)" "prognostic unfavorable (7.30e-4)" "unprognostic (3.28e-2)" "prognostic unfavorable (2.19e-5)" "unprognostic (7.85e-2)" "unprognostic (2.06e-1)" "unprognostic (2.02e-1)" "unprognostic (2.84e-2)" 35.8 40.1 54.8 22.4 65.0 48.1 31.9 62.9 76.0 36.6 54.2 49.1 21.2 41.4 26.3 40.0 33.3 25.6 118.9 51.5 66.1 26.8 33.9 24.6 30.0 63.7 60.6 49.2 34.3 32.5 25.5 39.0 64.9 38.0 20.1 42.2 29.7 32.6 788.7 21.9 22.4 36.2 60.5 23.1 32.3 132.4 60.8 50.5 31.4 451.3 30.5 38.5 28.3 93.2 144.2 65.8 138.8 108.5 104.6 118.4 62.7 111.9 114.0 123.1 120.5 97.5 70.9 73.3 179.8 77.7 193.9 67.6 113.3 68.8 171.0 97.4 76.1 74.3 88.9 112.7 110.8 46.6 58.5 125.7 77.0 62.3 147.8 183.7 126.1 70.5 60.7 86.0 157.1 52.2 89.4 78.3 156.8 88.8 71.2 61.0 177.5 78.6 95.4 44.6 58.4 74.6 96.8 110.9 149.9 193.7 154.7 88.5 101.3 92.0 102.3 58.1 223.3 79.0 108.9 86.9 96.0 65.9 120.2 9.4 12.6 10.0 11.7 13.7 12.2 12.9 12.3 10.6 14.4 9.1 15.5 12.9 10.9 11.6 10.4 10.2 22.2 9.6 54.8 65.0 62.9 76.0 51.5 66.1 63.7 60.6 64.9 60.5 60.8 93.2 89.1 64.1 75.0 58.1 81.1 78.4 97.6 68.5 78.6 72.6 67.7 72.3 224.6 48.6 74.8 35.0 56.3 96.8 93.5 28.9 58.7 84.5 986.2 158.2 132.1 78.1 53.8 105.6 75.6 75.8 99.5 78.6 33.6 114.8 126.6 106.3 62.4 70.2 67.9 87.5 87.8 36.1 40.7 76.6 58.7 1759.0 84.2 73.2 49.8 48.7 138.5 97.5 52.5 86.5 137.5 73.3 39.2 76.0 74.3 68.8 62.1 106.8 104.1 86.5 32.9 116.3 89.1 318.6 113.5 57.9 70.6 61.2 87.3 97.4 42.8 67.1 FXR2 FMR1L2 ENSG00000129245 "FMR1 autosomal homolog 2" P51116 17 7591230-7614897 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 120.9" "Cell type enhanced" "Detected in many" "Horizontal cells: 63.9;Rod photoreceptor cells: 55.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011205, HPA022997" Supported Supported Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 62: Horizontal cells - Visual perception" Cytosol "CAB011205: AB_476964, HPA022997: AB_1849208" "unprognostic (9.57e-2)" "unprognostic (1.23e-1)" "unprognostic (5.15e-3)" "unprognostic (2.61e-1)" "unprognostic (1.62e-1)" "unprognostic (7.56e-3)" "unprognostic (1.96e-1)" "unprognostic (3.50e-3)" "unprognostic (2.15e-1)" "unprognostic (2.18e-1)" "prognostic favorable (3.49e-6)" "unprognostic (2.79e-1)" "unprognostic (1.28e-2)" "unprognostic (2.46e-1)" "unprognostic (2.64e-1)" "unprognostic (7.79e-2)" "unprognostic (7.67e-2)" 19.7 27.9 31.5 11.4 34.3 9.8 17.4 36.5 37.9 21.2 26.9 26.7 13.9 21.7 11.6 20.9 20.1 10.9 66.0 33.2 40.0 22.2 20.6 19.2 14.1 41.1 40.9 20.4 16.2 30.7 33.0 15.5 43.4 21.6 11.5 37.7 19.9 18.2 120.9 22.5 17.4 17.1 33.4 16.8 19.9 27.4 37.2 20.8 17.1 84.4 15.1 23.3 19.4 34.9 36.6 48.3 43.8 45.7 36.7 25.0 33.7 54.2 45.1 77.2 53.2 27.2 11.9 33.8 34.8 37.2 34.1 40.1 58.2 24.8 51.4 39.1 62.4 19.6 42.2 15.9 35.7 0.2 39.8 23.5 35.8 58.8 56.4 43.3 27.1 26.9 35.4 11.6 38.8 18.6 26.9 19.3 26.2 18.9 25.8 37.9 26.6 21.3 28.2 13.0 26.1 47.2 37.3 24.3 37.8 41.3 25.3 14.5 24.3 36.0 22.5 24.0 64.8 19.0 18.6 15.5 41.3 15.8 48.0 2.6 0.8 2.5 0.9 1.0 1.3 0.5 1.5 1.9 1.3 0.9 1.2 1.3 2.1 1.0 0.6 0.9 1.8 0.8 31.5 34.3 36.5 37.9 33.2 40.0 41.1 40.9 43.4 33.4 37.2 34.9 10.3 32.1 17.9 10.7 7.7 11.5 15.4 7.9 2.8 46.9 10.4 8.3 41.7 8.6 9.5 16.5 31.3 15.9 15.1 12.0 1.9 11.6 1.8 11.1 9.2 10.5 9.6 15.6 10.3 9.3 11.5 10.8 10.7 11.0 2.5 12.9 15.0 11.7 9.1 63.9 12.0 10.1 10.2 7.3 9.7 2.7 9.6 7.1 0.0 3.7 7.4 23.3 16.5 8.5 12.4 17.6 12.5 15.4 6.3 15.4 15.5 8.9 7.6 55.8 6.6 14.2 17.7 22.9 28.2 8.7 14.3 17.1 7.6 14.6 7.4 10.3 FXYD4 CHIF ENSG00000150201 "FXYD domain containing ion transport regulator 4" P59646 10 43371636-43376335 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 43 "kidney: 297.7" "Cell type enriched" "Detected in some" 107 "Collecting duct cells: 5039.3" "Group enriched" "Detected in many" 5 "renal cancer: 10.7;urothelial cancer: 20.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 29 "SuSa: 10.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA058421 Enhanced Uncertain Cytosol NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA058421: AB_2683714" "unprognostic (2.92e-3)" "unprognostic (5.25e-1)" "unprognostic (9.46e-2)" "unprognostic (2.60e-2)" "unprognostic (2.56e-1)" "unprognostic (1.85e-1)" "unprognostic (2.32e-1)" "unprognostic (2.00e-1)" "unprognostic (5.17e-2)" "unprognostic (2.19e-1)" "unprognostic (6.12e-2)" "unprognostic (7.88e-2)" "unprognostic (1.26e-1)" "unprognostic (3.20e-1)" "unprognostic (2.09e-2)" 0.1 0.0 1.5 0.0 2.6 0.0 0.0 1.5 2.7 0.0 1.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.3 1.4 2.0 297.7 0.0 1.1 0.0 1.6 2.2 0.0 0.0 0.0 0.1 0.0 1.7 0.1 0.0 0.0 5.6 2.7 1.3 0.0 0.0 0.0 1.4 0.0 6.9 0.8 2.2 0.0 0.0 0.4 0.0 1.7 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.6 1.5 2.7 1.4 2.0 1.6 2.2 1.7 1.4 2.2 2.7 0.0 6.4 1.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.1 5039.3 0.0 0.5 0.0 0.5 46.9 0.0 2.6 6.4 2.6 0.0 0.0 0.0 0.0 0.2 0.1 0.4 9.2 15.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 0.0 11.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.2 0.1 0.1 8.0 0.0 0.0 0.0 0.0 0.1 1.4 0.1 0.0 0.0 0.4 0.3 0.1 1.0 1.4 G3BP1 "G3BP, HDH-VIII" ENSG00000145907 "G3BP stress granule assembly factor 1" Q13283 5 151771045-151812911 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Immunity, Innate immunity, Transport" "DNA-binding, Endonuclease, Helicase, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004052, CAB037068" Supported Supported Cytosol NA NA 280000 "Cluster 13: T-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 28: Keratinocytes - Keratinization" Cytosol "CAB037068: AB_1840864, HPA004052: AB_1849348" "unprognostic (1.31e-1)" "unprognostic (3.94e-2)" "unprognostic (1.19e-3)" "unprognostic (1.28e-2)" "unprognostic (1.05e-1)" "unprognostic (3.09e-2)" "unprognostic (1.03e-3)" "unprognostic (1.83e-2)" "unprognostic (1.44e-1)" "unprognostic (1.36e-1)" "unprognostic (2.06e-3)" "unprognostic (1.23e-2)" "prognostic unfavorable (3.33e-4)" "unprognostic (1.97e-1)" "unprognostic (1.33e-1)" "unprognostic (2.11e-2)" "unprognostic (3.88e-2)" 52.3 46.8 32.9 60.2 36.1 27.5 54.1 42.8 44.6 42.0 41.0 47.8 34.8 42.5 33.1 54.8 51.0 38.8 51.0 30.7 36.1 57.1 69.0 36.1 78.3 34.5 35.7 62.5 30.4 41.5 16.5 58.2 35.8 41.3 50.6 18.3 31.8 37.3 112.2 43.4 33.9 47.8 35.0 46.7 40.3 65.5 38.6 66.0 42.6 92.1 85.7 66.3 31.9 43.3 204.9 267.0 177.0 96.3 253.2 119.2 232.4 204.1 190.6 290.6 348.6 413.7 310.3 384.7 307.0 188.0 231.6 210.9 319.7 395.6 333.7 122.5 173.8 232.9 201.1 334.8 128.8 281.6 163.9 123.4 186.7 243.7 232.2 98.7 209.7 140.9 191.3 173.3 254.5 179.7 273.9 142.4 231.4 146.0 209.6 254.3 235.1 187.2 163.1 290.5 195.2 132.0 200.8 307.0 319.3 169.2 246.3 174.7 238.2 202.0 239.7 187.3 364.0 104.9 171.3 305.0 132.2 229.6 337.8 132.2 102.3 84.7 189.2 135.4 255.3 168.8 215.6 186.7 141.0 160.0 201.8 193.2 37.8 203.7 134.1 134.7 249.2 287.2 32.9 36.1 42.8 44.6 30.7 36.1 34.5 35.7 35.8 35.0 38.6 43.3 88.9 19.2 41.4 32.7 112.0 239.5 101.3 82.4 148.0 37.1 74.8 60.7 62.3 44.3 66.2 64.4 16.7 94.0 91.7 47.3 78.2 69.6 49.6 80.6 104.4 112.1 50.2 96.1 25.7 53.0 94.6 98.0 70.3 87.2 73.6 73.8 76.8 169.4 78.2 57.2 30.6 59.4 50.8 81.2 195.0 30.1 65.0 73.3 87.2 37.5 83.7 54.3 45.3 29.7 45.3 59.2 42.9 57.2 89.3 160.0 33.5 80.0 74.2 36.6 39.5 111.6 90.7 58.0 89.3 155.6 256.4 67.3 99.6 72.2 78.5 98.0 G3BP2 KIAA0660 ENSG00000138757 "G3BP stress granule assembly factor 2" Q9UN86 4 75641849-75724589 "Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity, mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018304, HPA018425" Enhanced Enhanced Cytosol NA NA 47000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA018304: AB_1849350, HPA018425: AB_1849352" "unprognostic (2.42e-2)" "unprognostic (5.79e-2)" "unprognostic (8.70e-3)" "unprognostic (2.23e-1)" "unprognostic (6.98e-2)" "unprognostic (5.10e-2)" "unprognostic (2.05e-2)" "unprognostic (1.04e-1)" "unprognostic (6.83e-2)" "unprognostic (3.79e-1)" "unprognostic (7.38e-2)" "unprognostic (7.88e-2)" "prognostic favorable (6.65e-5)" "unprognostic (3.10e-1)" "unprognostic (1.12e-1)" "unprognostic (1.27e-2)" "unprognostic (6.99e-2)" 37.6 41.5 32.6 50.9 35.6 69.2 50.3 24.2 48.5 47.2 12.9 61.7 52.4 45.1 32.1 49.5 55.2 49.7 47.8 33.7 51.7 67.5 65.3 46.0 60.2 26.0 28.8 32.0 42.2 56.0 28.2 38.4 32.4 77.8 58.0 46.8 37.0 49.2 115.1 25.5 62.6 55.0 24.0 48.0 47.5 60.5 40.0 66.5 74.6 119.5 61.2 65.8 25.8 30.0 96.8 96.6 160.5 131.1 134.8 136.6 54.1 141.6 144.6 96.2 101.5 128.5 137.1 197.1 125.5 120.1 87.0 68.8 170.1 176.0 136.6 111.4 66.2 185.7 95.7 141.7 119.8 188.4 146.2 109.9 144.4 114.6 122.8 129.1 172.1 114.9 140.9 139.2 150.7 63.0 218.4 63.1 154.1 140.3 36.3 159.8 199.2 96.3 112.3 125.8 124.1 141.1 105.7 151.0 201.9 165.7 75.1 90.9 178.5 95.3 76.5 107.7 81.7 136.2 133.9 195.2 135.5 122.9 122.7 83.1 36.2 62.4 50.0 47.8 76.4 35.1 48.1 55.8 41.1 28.2 46.9 51.5 30.8 59.6 64.1 18.5 44.1 64.1 32.6 35.6 24.2 48.5 33.7 51.7 26.0 28.8 32.4 24.0 40.0 30.0 72.8 54.5 100.7 26.1 126.3 89.0 81.7 53.2 114.4 61.4 71.8 55.2 79.1 20.0 81.0 53.3 50.1 36.4 133.0 92.2 41.1 59.0 213.8 84.7 57.8 69.8 135.4 43.9 70.6 68.9 49.3 56.7 65.2 80.0 105.7 76.7 51.0 77.7 45.7 70.7 74.9 107.9 50.8 75.9 131.3 228.8 26.4 86.1 60.5 30.9 85.3 29.3 53.5 36.7 59.1 94.8 66.6 39.9 117.7 84.5 88.3 104.1 85.8 69.1 19.7 57.2 91.9 63.2 74.8 79.8 77.7 41.3 186.2 99.5 75.6 88.3 GALNS "GALNAC6S, GAS" ENSG00000141012 "Galactosamine (N-acetyl)-6-sulfatase" P34059 16 88813734-88856970 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Dwarfism, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 51.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 11.3;granulocytes: 31.3;monocytes: 17.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026404, HPA042433, HPA074225" Supported Approved Cytosol "Intracellular and membrane" NA NA 2000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 18: U-2197 - ECM organization" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Cytosol "CAB026404: , HPA042433: AB_2732499, HPA074225: " "unprognostic (3.16e-1)" "unprognostic (9.98e-2)" "unprognostic (4.03e-3)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "unprognostic (8.08e-3)" "prognostic unfavorable (3.66e-4)" "unprognostic (4.15e-3)" "unprognostic (1.32e-1)" "unprognostic (4.84e-3)" "unprognostic (2.00e-1)" "unprognostic (3.53e-2)" "unprognostic (4.12e-3)" "unprognostic (4.24e-2)" "unprognostic (5.54e-2)" "unprognostic (3.59e-2)" "unprognostic (6.84e-2)" 9.2 12.8 9.4 9.3 10.0 22.2 6.3 10.0 11.5 9.1 22.1 10.0 10.6 7.4 14.5 8.8 11.4 9.7 11.0 10.6 12.0 8.6 8.1 10.4 7.4 12.6 16.4 6.7 5.0 8.6 11.9 8.6 12.0 7.7 6.1 3.3 8.3 4.7 6.4 8.4 10.6 7.1 10.8 9.1 8.1 26.3 11.3 4.8 9.1 3.6 5.6 9.0 9.1 12.0 5.7 42.7 6.2 43.4 47.1 22.4 41.9 17.9 27.3 19.1 14.7 22.7 36.8 7.1 37.1 29.2 28.8 33.0 9.0 14.2 11.4 4.7 13.8 4.5 17.0 13.2 31.5 3.6 28.5 31.4 26.9 21.4 6.0 27.0 16.4 7.8 9.9 4.1 11.3 33.3 9.2 15.0 14.2 14.3 19.6 19.6 5.4 12.1 11.9 13.2 15.8 12.2 42.4 4.0 21.9 14.4 27.3 32.5 31.3 41.8 31.5 43.2 10.0 4.3 4.5 12.6 45.2 29.7 25.4 1.4 17.4 31.3 4.5 12.5 3.9 3.0 2.5 4.0 11.3 1.3 2.5 3.1 21.7 4.0 9.6 4.7 4.6 8.5 9.4 10.0 10.0 11.5 10.6 12.0 12.6 16.4 12.0 10.8 11.3 12.0 4.8 16.0 4.8 9.4 5.9 6.5 7.3 27.7 9.1 5.0 6.8 5.0 8.4 4.3 11.0 3.7 6.2 9.9 8.5 16.8 3.9 5.7 21.0 27.2 9.6 7.2 12.0 1.3 7.6 3.7 14.0 13.8 6.1 8.9 1.3 11.9 7.5 6.4 18.7 25.2 10.4 6.8 8.2 13.2 6.3 37.3 7.2 11.3 7.2 2.8 18.2 8.8 14.4 4.0 9.8 5.6 13.6 6.8 9.9 6.7 17.3 5.9 35.1 10.0 6.6 9.4 9.0 51.3 42.8 6.3 5.7 15.9 7.9 16.5 10.1 6.8 GALT ENSG00000213930 "Galactose-1-phosphate uridylyltransferase" P07902 9 34638133-34651035 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Galactose metabolism" "Nucleotidyltransferase, Transferase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 50.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004868, HPA005729" Enhanced Approved Cytosol NA NA 260000 "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA004868: AB_1079130, HPA005729: AB_1079131" "unprognostic (2.38e-1)" "unprognostic (8.92e-2)" "unprognostic (1.45e-3)" "unprognostic (1.54e-1)" "unprognostic (5.46e-2)" "unprognostic (1.22e-1)" "unprognostic (2.94e-1)" "unprognostic (2.13e-1)" "unprognostic (3.97e-2)" "unprognostic (1.13e-2)" "prognostic favorable (3.11e-5)" "unprognostic (9.68e-2)" "prognostic favorable (6.25e-6)" "unprognostic (7.90e-2)" "unprognostic (2.74e-1)" "unprognostic (3.56e-1)" "unprognostic (7.75e-2)" 6.7 14.0 5.3 6.7 5.9 8.1 6.3 5.5 6.5 6.9 4.6 8.5 18.3 6.9 5.3 5.3 7.8 6.8 10.4 5.2 6.3 10.0 50.0 6.6 12.0 5.5 5.7 8.2 7.5 13.0 6.1 9.2 5.3 6.4 6.7 6.3 12.3 7.5 10.2 15.2 16.5 4.0 4.5 9.7 8.1 2.4 6.1 7.8 8.2 7.6 7.7 5.3 6.1 4.7 5.5 7.5 6.8 2.4 9.0 9.2 7.8 4.2 12.1 4.3 5.1 9.5 4.8 6.1 4.2 5.2 1.6 2.9 1.3 11.8 0.8 9.7 4.8 2.5 14.7 9.8 8.7 1.4 2.9 12.6 7.4 2.7 3.6 9.3 10.6 8.3 2.3 6.4 7.3 5.1 5.4 10.3 2.3 6.7 1.3 8.4 5.9 3.3 12.5 7.8 1.6 5.7 5.0 9.8 5.4 5.0 9.2 8.2 1.6 1.7 3.4 3.4 0.0 3.9 2.4 1.3 4.1 4.4 10.8 16.5 23.7 11.7 15.4 21.5 21.3 24.8 25.2 21.1 21.5 13.2 15.3 14.8 4.6 29.0 20.4 18.2 30.0 17.6 5.3 5.9 5.5 6.5 5.2 6.3 5.5 5.7 5.3 4.5 6.1 4.7 12.6 6.4 21.2 10.7 19.0 21.7 13.4 19.3 19.4 44.0 10.5 12.1 25.7 14.3 15.4 16.5 47.9 72.5 13.9 17.3 29.4 18.3 7.6 7.8 11.8 14.6 16.3 13.7 9.1 7.3 36.3 18.3 9.2 8.0 20.3 24.7 23.6 69.9 24.1 47.1 12.5 17.0 26.4 15.5 8.7 36.8 18.3 12.4 21.4 5.6 15.9 18.7 34.0 6.0 3.7 6.9 37.5 13.9 10.7 4.7 67.1 46.3 11.1 38.5 6.6 11.2 12.2 4.8 6.6 8.6 20.2 59.1 25.5 27.4 20.4 9.2 GANC ENSG00000214013 "Glucosidase alpha, neutral C" Q8TET4 15 42273233-42356935 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 47.9;Oligodendrocytes: 86.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016949, HPA051522" Approved Approved Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA016949: AB_1849465, HPA051522: " "unprognostic (8.83e-2)" "unprognostic (1.68e-1)" "unprognostic (2.24e-1)" "unprognostic (3.04e-3)" "unprognostic (2.51e-2)" "unprognostic (9.85e-2)" "unprognostic (2.49e-2)" "prognostic favorable (9.76e-4)" "unprognostic (1.73e-1)" "unprognostic (1.43e-1)" "unprognostic (1.66e-2)" "unprognostic (1.46e-1)" "unprognostic (1.14e-1)" "unprognostic (1.05e-2)" "unprognostic (3.14e-1)" "unprognostic (1.55e-2)" "unprognostic (3.74e-2)" 8.9 7.6 8.2 10.3 13.0 14.3 8.8 9.8 10.4 9.6 10.4 10.6 8.9 11.0 17.8 12.1 8.6 9.4 8.5 7.8 9.2 9.4 13.3 20.4 10.0 12.4 11.1 13.0 8.4 11.3 7.9 8.0 13.2 8.5 12.4 9.7 14.5 8.7 12.9 10.1 9.8 9.8 10.0 11.9 8.5 12.3 10.8 10.3 12.1 10.6 10.2 8.3 9.3 19.2 9.0 4.9 10.7 11.6 12.3 17.2 7.1 19.2 19.7 19.7 16.4 6.4 6.2 4.9 10.2 18.6 14.3 18.3 12.6 19.5 13.6 12.3 6.0 11.9 12.1 12.8 10.4 11.6 10.1 11.8 11.4 8.1 13.6 11.7 13.5 12.0 12.6 13.0 15.8 1.7 7.9 12.7 6.7 4.3 5.5 14.7 12.4 17.0 14.7 8.4 8.2 11.7 10.8 9.4 7.0 5.6 3.3 27.0 13.6 21.6 5.7 17.8 12.1 13.9 20.7 9.7 10.4 20.9 12.1 16.8 11.8 10.2 4.5 13.1 6.2 19.6 7.2 8.6 15.5 23.1 8.9 5.4 6.7 5.7 10.9 12.3 7.3 6.5 8.2 13.0 9.8 10.4 7.8 9.2 12.4 11.1 13.2 10.0 10.8 19.2 6.2 19.2 47.9 35.6 14.5 10.5 17.1 7.9 12.0 5.6 5.6 6.2 8.2 4.3 8.9 1.8 10.4 5.3 4.0 9.5 5.9 5.9 18.6 7.7 11.1 5.0 4.2 5.0 18.9 3.8 5.1 8.1 9.7 11.9 10.8 8.1 5.7 12.4 6.5 3.3 28.5 5.7 10.2 11.7 5.4 4.7 7.2 10.9 14.2 36.5 14.0 9.5 7.2 31.7 86.7 5.4 15.7 6.4 7.1 9.1 7.9 7.7 9.8 8.5 13.1 9.2 7.0 20.5 15.7 18.9 5.3 2.9 6.9 6.4 8.5 20.7 GAREM2 "FAM59B, FLJ00375, GAREML, KIAA2038" ENSG00000157833 "GRB2 associated regulator of MAPK1 subtype 2" Q75VX8 2 26173088-26189663 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 37.2;choroid plexus: 10.4;parathyroid gland: 22.9" "Group enriched" "Detected in many" 4 "Distal tubular cells: 46.9;Muller glia cells: 19.5;Proximal tubular cells: 42.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 16.8;SH-SY5Y: 10.2;U-2 OS: 13.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071575 Approved Cytosol NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA071575: AB_2686420" "unprognostic (1.70e-2)" "unprognostic (5.62e-2)" "unprognostic (7.61e-4)" "unprognostic (1.56e-2)" "unprognostic (8.27e-2)" "unprognostic (2.19e-1)" "unprognostic (2.90e-2)" "unprognostic (1.99e-1)" "unprognostic (2.12e-2)" "unprognostic (2.65e-1)" "unprognostic (1.33e-1)" "unprognostic (3.94e-2)" "unprognostic (1.15e-3)" "unprognostic (1.35e-1)" "unprognostic (3.22e-1)" "unprognostic (1.46e-2)" "unprognostic (1.04e-1)" 2.2 0.8 27.1 1.1 30.8 0.4 1.9 30.1 22.5 2.3 10.4 3.3 0.6 3.2 0.9 1.5 2.5 1.7 3.0 21.3 26.2 2.0 0.2 1.0 1.5 32.9 32.0 3.6 2.9 22.9 2.3 0.8 27.7 1.8 1.8 3.3 1.4 2.1 2.7 1.4 1.6 2.3 27.0 1.4 2.0 2.6 37.2 0.6 1.7 2.5 1.2 2.7 2.1 23.5 3.0 4.4 5.2 0.4 0.9 1.8 0.4 1.6 0.0 0.5 0.4 8.5 1.0 0.0 2.1 3.4 5.3 0.1 16.8 0.0 0.7 1.9 6.2 1.5 1.5 0.5 6.2 0.1 0.3 2.5 0.8 2.5 0.2 0.3 2.0 4.1 8.1 0.1 3.1 0.0 0.4 0.6 5.6 0.5 1.2 1.7 0.0 0.1 2.7 0.9 1.1 10.2 3.7 0.4 3.2 1.5 0.2 9.0 0.9 2.3 13.8 4.1 0.1 0.3 0.0 1.9 0.1 0.0 3.0 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.3 0.2 0.1 0.1 0.2 0.1 0.2 0.0 0.1 0.5 0.0 0.0 27.1 30.8 30.1 22.5 21.3 26.2 32.9 32.0 27.7 27.0 37.2 23.5 1.2 0.0 0.0 0.0 1.8 0.0 0.4 0.0 0.0 1.0 0.5 0.9 0.0 1.5 0.0 3.7 2.1 0.4 1.2 1.3 46.9 2.2 4.4 0.5 2.2 1.7 0.0 0.4 0.0 1.6 2.6 3.8 3.6 0.5 0.0 0.8 0.4 0.0 0.6 0.0 0.0 0.7 0.0 0.3 0.0 7.6 2.1 1.1 0.0 0.0 0.6 19.5 2.1 0.0 0.0 1.6 1.2 3.4 0.1 1.1 0.1 42.1 0.0 1.2 6.6 1.6 1.7 1.9 6.2 0.1 0.0 0.3 2.3 0.4 1.5 0.3 GARS1 "CMT2D, DSMAV, GARS, GlyRS, SMAD1" ENSG00000106105 "Glycyl-tRNA synthetase 1" P41250 7 30580533-30634033 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Hydrolase, Ligase, Transferase" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 34.1;Cytotrophoblasts: 47.0;Extravillous trophoblasts: 70.0;Hofbauer cells: 44.3;Syncytiotrophoblasts: 39.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017896, HPA019097" Enhanced Supported Cytosol "Intracellular and membrane" NA NA 560000 "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA017896: AB_1849478, HPA019097: AB_1849480" "prognostic unfavorable (1.02e-4)" "unprognostic (2.46e-2)" "unprognostic (5.45e-2)" "prognostic unfavorable (8.48e-4)" "unprognostic (2.04e-1)" "unprognostic (1.57e-3)" "prognostic unfavorable (8.95e-5)" "unprognostic (7.31e-3)" "unprognostic (4.76e-1)" "unprognostic (4.00e-3)" "unprognostic (1.77e-1)" "unprognostic (4.45e-2)" "prognostic unfavorable (1.70e-5)" "unprognostic (3.92e-1)" "unprognostic (3.40e-2)" "unprognostic (6.32e-2)" "prognostic unfavorable (3.04e-5)" 34.2 31.0 33.3 43.3 36.5 32.0 31.7 34.2 46.2 32.6 49.9 39.8 27.6 29.1 37.3 53.8 23.3 29.9 32.9 38.6 45.7 42.7 46.0 34.0 47.2 38.1 34.7 26.7 78.5 58.1 36.5 39.9 42.0 26.8 48.6 46.9 36.1 29.3 48.1 43.4 26.0 49.8 33.2 22.3 47.4 51.5 43.4 40.7 51.5 45.0 67.3 54.0 29.4 35.2 231.4 119.8 103.4 364.5 191.9 286.8 172.0 332.4 330.5 184.0 369.8 159.5 115.4 375.9 96.2 443.1 281.6 174.5 262.6 230.2 327.7 92.9 82.5 182.6 84.8 141.1 604.0 267.6 149.8 272.5 391.9 265.8 304.9 128.1 241.6 354.1 350.2 465.4 296.7 154.7 216.8 204.3 259.6 222.4 183.4 114.0 90.1 299.0 219.5 109.1 117.9 177.4 88.1 261.5 509.2 182.8 225.3 409.3 208.2 82.2 262.9 164.9 217.9 403.8 390.8 445.9 289.4 398.8 392.9 40.0 27.0 24.1 22.9 35.8 27.4 21.0 26.0 28.8 35.8 16.3 25.2 30.2 5.2 20.9 41.7 18.5 31.9 23.9 33.3 36.5 34.2 46.2 38.6 45.7 38.1 34.7 42.0 33.2 43.4 35.2 10.7 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.1 0.0 0.0 0.0 0.0 47.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 70.0 13.6 0.0 0.0 0.0 0.0 0.0 0.0 44.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 39.8 2.0 0.0 0.0 0.0 GBE1 ENSG00000114480 "1,4-alpha-glucan branching enzyme 1" Q04446 3 81489703-81761645 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycogen biosynthesis" "Glycosyltransferase, Transferase" "Disease variant, Glycogen storage disease, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 149.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 287.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038073, HPA038074, HPA038075" Enhanced Approved Cytosol NA NA 6500000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA038073: AB_10673040, HPA038074: AB_10672403, HPA038075: AB_10674545" "unprognostic (3.10e-1)" "unprognostic (1.02e-3)" "unprognostic (6.76e-2)" "unprognostic (1.05e-2)" "unprognostic (3.48e-2)" "unprognostic (1.89e-1)" "unprognostic (9.01e-3)" "unprognostic (1.17e-2)" "unprognostic (2.65e-1)" "unprognostic (1.50e-1)" "unprognostic (2.19e-2)" "unprognostic (5.68e-2)" "unprognostic (1.46e-1)" "unprognostic (5.36e-2)" "unprognostic (4.42e-1)" "unprognostic (2.83e-3)" "unprognostic (3.78e-3)" 73.9 53.8 4.5 14.9 5.7 19.7 38.6 7.1 8.2 14.2 14.2 11.8 13.2 17.3 14.2 18.1 13.8 13.0 55.6 6.2 8.2 41.4 108.6 17.2 8.6 10.7 18.7 14.2 14.2 19.1 10.4 25.6 10.3 13.2 13.8 22.0 15.5 14.9 149.1 14.4 11.5 21.8 7.0 12.0 11.1 7.9 7.4 11.4 19.6 56.6 13.2 19.2 13.9 7.4 61.3 36.2 11.9 168.7 287.6 216.8 21.5 99.1 140.1 58.1 97.6 7.1 15.6 67.9 42.7 122.5 34.5 7.1 9.9 45.7 135.4 32.3 6.4 21.2 70.0 22.8 197.5 72.2 17.8 161.2 33.2 93.5 95.5 144.9 130.5 8.0 17.0 38.0 191.1 17.8 12.5 92.7 12.0 16.8 58.0 22.9 53.6 81.1 41.4 20.5 6.0 7.9 64.6 18.7 20.9 17.2 13.3 58.9 183.4 118.9 28.1 84.7 92.8 174.8 21.4 24.6 194.1 47.8 49.8 7.5 11.8 15.6 5.2 10.8 5.1 11.6 5.6 5.7 13.8 12.5 6.4 6.6 11.4 13.5 11.8 4.8 5.1 6.5 4.5 5.7 7.1 8.2 6.2 8.2 10.7 18.7 10.3 7.0 7.4 7.4 49.7 16.0 12.4 31.3 14.9 30.7 22.2 36.8 27.3 18.6 7.5 5.5 60.2 15.7 21.9 31.3 0.0 30.3 8.4 9.5 41.1 32.1 36.2 16.3 15.2 32.0 22.1 4.6 52.4 25.4 74.0 34.9 6.6 14.7 43.1 16.0 15.4 75.2 26.3 30.3 47.4 8.7 12.2 12.9 21.3 16.9 17.4 17.3 24.9 87.1 16.3 10.4 7.2 49.3 63.0 37.8 5.8 13.2 12.8 17.7 11.3 50.8 25.0 17.8 32.9 45.8 26.7 6.9 7.3 20.6 21.3 54.9 8.7 34.2 8.3 14.5 GCN1 "GCN1L, GCN1L1, KIAA0219" ENSG00000089154 "GCN1 activator of EIF2AK4" Q92616 12 120127202-120194715 "Plasma proteins, Predicted intracellular proteins" "Stress response, Translation regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018799, HPA019648, HPA024367" Enhanced Enhanced Cytosol NA NA 120000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 15: RT4 - Unknown function" "Cluster 59: Non-specific - Transcription" Cytosol "HPA018799: AB_1849565, HPA019648: AB_1849567, HPA024367: AB_1849569" "unprognostic (7.36e-2)" "unprognostic (2.10e-3)" "unprognostic (3.17e-1)" "unprognostic (2.60e-1)" "unprognostic (1.26e-1)" "unprognostic (3.14e-2)" "prognostic unfavorable (1.87e-8)" "unprognostic (5.24e-2)" "unprognostic (1.59e-1)" "unprognostic (1.20e-2)" "unprognostic (2.07e-1)" "unprognostic (1.75e-1)" "unprognostic (6.35e-2)" "unprognostic (1.21e-1)" "unprognostic (2.34e-1)" "unprognostic (7.09e-3)" "unprognostic (1.43e-1)" 17.2 16.5 9.5 16.0 11.6 19.1 16.9 10.3 10.1 17.1 12.7 18.7 12.1 20.0 9.5 22.3 17.3 9.5 16.1 8.9 9.4 16.2 17.8 16.0 18.3 11.6 10.6 20.2 22.9 18.0 21.1 16.5 10.0 15.8 12.4 8.8 18.2 12.7 44.4 22.0 18.1 14.7 9.2 20.5 20.5 17.9 11.8 18.3 19.7 22.9 16.3 18.6 16.4 13.4 51.4 99.3 35.1 39.7 54.4 32.7 122.4 44.9 38.9 45.8 37.2 85.6 34.5 67.8 49.6 64.8 29.0 49.5 82.1 63.5 28.4 45.5 66.9 84.0 65.5 59.8 35.2 78.2 51.5 40.3 36.3 54.3 50.9 40.2 42.5 30.3 100.3 17.0 38.8 51.6 49.7 59.1 62.3 48.8 59.9 59.7 36.0 67.3 31.2 172.8 57.4 57.4 73.8 31.7 26.5 33.1 67.5 43.8 58.6 37.3 41.0 24.7 47.0 66.2 65.4 67.1 35.7 40.5 38.2 0.7 1.8 1.3 3.3 1.7 4.1 2.0 2.6 2.7 2.3 2.1 1.9 2.1 0.0 1.8 4.1 2.7 2.6 1.9 9.5 11.6 10.3 10.1 8.9 9.4 11.6 10.6 10.0 9.2 11.8 13.4 12.0 9.6 17.9 0.0 11.2 0.0 6.8 0.0 9.6 14.1 11.9 13.6 0.0 12.8 9.3 22.0 10.4 14.2 12.0 8.1 1.9 15.6 1.9 9.0 14.1 10.5 3.6 16.2 0.0 15.9 38.2 10.5 25.5 14.9 5.1 25.7 10.4 24.6 11.2 16.8 0.0 11.4 0.0 9.1 0.0 3.5 14.3 8.9 0.0 0.0 11.1 9.0 7.2 0.0 0.0 18.6 8.6 12.8 17.7 15.7 11.1 9.1 2.9 12.1 6.6 16.4 8.9 8.8 20.8 14.1 0.0 14.6 10.1 14.3 11.7 15.8 GCSAML "C1orf150, FLJ44728" ENSG00000169224 "Germinal center associated signaling and motility like" Q5JQS6 1 247507058-247577690 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.4;prostate: 5.5" "Cell type enriched" "Detected in some" 24 "granulocytes: 223.3" "Cancer enriched" "Detected in single" 13 "prostate cancer: 1.9" "Region enriched" "Detected in some" 5 "cerebellum: 6.4" "Immune cell enriched" "Detected in single" 661 "basophil: 227.7" "Lineage enriched" "Detected in single" 661 "granulocytes: 227.7" "Group enriched" "Detected in some" 71 "HEL: 151.8;HMC-1: 564.8" "Low region specificity" "Detected in all" "HPA027507, HPA027510" Uncertain Approved Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" Cytosol "HPA027507: AB_10600756, HPA027510: AB_2672309" "unprognostic (5.68e-2)" "unprognostic (1.86e-1)" "unprognostic (4.07e-3)" "unprognostic (3.48e-2)" "unprognostic (1.72e-1)" "unprognostic (2.76e-4)" "unprognostic (3.21e-1)" "unprognostic (6.14e-2)" "unprognostic (5.42e-2)" "unprognostic (2.00e-1)" "unprognostic (1.11e-1)" "unprognostic (1.81e-1)" "unprognostic (9.51e-3)" "unprognostic (3.13e-2)" "unprognostic (2.83e-1)" "unprognostic (1.24e-1)" "unprognostic (1.40e-2)" 0.5 0.2 0.4 0.8 0.4 1.8 1.0 6.4 0.7 0.7 0.4 1.2 1.5 0.8 0.5 1.1 0.3 1.4 0.2 0.3 0.4 0.1 0.2 2.1 0.3 0.4 0.3 0.1 0.4 0.1 0.0 0.3 1.2 5.5 1.5 1.2 0.3 0.4 0.2 0.7 1.4 0.6 0.1 0.4 0.9 3.4 0.4 0.7 0.3 0.7 0.2 0.7 0.3 1.2 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.8 0.8 0.2 0.1 0.0 0.1 151.8 0.2 0.0 0.0 0.3 564.8 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 1.0 0.1 0.3 0.3 5.0 0.2 0.1 0.0 0.2 0.1 0.3 0.0 0.1 0.1 0.4 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.5 0.4 0.0 0.0 0.3 0.2 0.0 2.3 0.1 0.4 227.7 0.1 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.1 0.3 0.3 0.2 0.2 0.2 0.2 0.1 0.2 0.5 0.4 0.4 6.4 0.7 0.3 0.4 0.4 0.3 1.2 0.1 0.4 1.2 0.0 0.0 4.4 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 1.9 0.0 9.1 0.0 0.1 0.6 0.0 5.0 0.4 0.0 0.0 0.3 0.0 0.0 223.3 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.7 7.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.3 2.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 8.3 1.7 0.0 0.6 0.0 1.4 0.1 0.0 0.2 GDI1 "FLJ41411, GDIL, MRX41, MRX48, OPHN2, RABGDIA, XAP-4" ENSG00000203879 "GDP dissociation inhibitor 1" P31150 X 154436913-154443467 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 438.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012979, HPA049290, HPA057668" Enhanced Approved Cytosol NA NA 31000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 58: T-cells - T-cell receptor" Cytosol "CAB012979: AB_2533970, HPA049290: AB_2680700, HPA057668: AB_2683498" "prognostic unfavorable (6.84e-4)" "unprognostic (1.13e-2)" "prognostic unfavorable (3.83e-5)" "unprognostic (3.53e-1)" "unprognostic (1.22e-1)" "unprognostic (1.92e-3)" "unprognostic (1.31e-3)" "unprognostic (1.36e-1)" "unprognostic (1.46e-2)" "unprognostic (1.30e-1)" "unprognostic (2.98e-3)" "unprognostic (3.86e-2)" "unprognostic (3.88e-3)" "unprognostic (1.70e-1)" "unprognostic (8.12e-2)" "unprognostic (1.92e-2)" "unprognostic (1.72e-1)" 77.3 85.9 351.5 54.9 381.7 41.2 67.4 309.6 438.5 99.7 214.0 91.8 36.7 92.2 46.2 57.5 94.6 47.3 99.1 391.8 349.9 74.4 53.9 90.1 53.9 344.5 312.7 120.0 54.7 63.4 176.0 60.4 349.5 74.9 41.7 130.9 49.7 69.5 62.9 61.6 67.5 78.9 311.4 89.4 68.5 54.1 330.6 58.7 63.0 70.8 51.1 89.2 81.2 366.2 100.2 88.9 195.9 164.6 77.7 91.4 64.5 149.6 91.1 140.4 146.0 52.6 51.1 79.5 149.3 139.4 213.2 79.7 172.7 83.9 96.5 147.5 93.8 25.0 142.6 35.5 113.5 24.6 90.5 94.7 101.3 163.4 99.6 154.6 92.4 95.7 31.1 120.5 169.4 99.2 77.9 62.1 53.0 106.1 168.8 77.6 51.6 45.0 98.8 46.5 272.5 210.3 67.6 86.1 109.0 150.3 50.9 42.5 110.4 131.9 116.8 138.4 212.0 182.1 202.0 128.3 140.7 54.5 162.5 23.7 8.4 26.9 12.1 12.6 18.0 9.9 13.0 12.0 7.0 10.1 10.0 10.1 30.0 8.7 21.3 12.1 16.2 7.3 351.5 381.7 309.6 438.5 391.8 349.9 344.5 312.7 349.5 311.4 330.6 366.2 39.3 16.0 27.4 30.3 35.9 27.1 24.8 48.3 33.6 71.3 24.1 25.7 62.6 24.3 29.0 27.6 25.0 22.7 27.0 31.4 31.3 39.4 2.9 33.1 41.1 35.3 90.8 9.2 48.8 31.3 39.3 37.5 37.8 34.3 33.7 29.7 30.4 17.7 36.3 60.6 43.2 24.8 65.1 35.9 40.9 6.0 37.6 35.5 17.8 22.5 59.0 37.7 19.6 33.2 46.4 50.2 25.9 39.9 35.7 27.4 24.3 25.5 46.8 37.1 52.6 29.5 49.8 33.9 66.6 20.7 30.3 49.5 43.2 22.0 15.0 26.2 GDI2 RABGDIB ENSG00000057608 "GDP dissociation inhibitor 2" P50395 10 5765223-5842132 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049290, HPA057668" Supported Approved Cytosol NA NA 53000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 3: Monocytes - Immune response regulation" Cytosol "HPA049290: AB_2680700, HPA057668: AB_2683498" "unprognostic (1.08e-2)" "unprognostic (8.33e-3)" "unprognostic (5.25e-2)" "unprognostic (1.13e-1)" "prognostic favorable (9.26e-4)" "unprognostic (7.15e-2)" "prognostic unfavorable (7.56e-7)" "unprognostic (1.36e-1)" "unprognostic (1.37e-1)" "unprognostic (1.74e-2)" "unprognostic (6.97e-2)" "unprognostic (3.10e-1)" "unprognostic (4.09e-2)" "unprognostic (1.71e-2)" "unprognostic (5.33e-2)" "unprognostic (2.02e-1)" "unprognostic (5.68e-2)" 125.1 111.5 62.4 151.6 70.0 126.6 138.1 76.0 90.3 120.6 66.8 152.9 175.4 96.3 115.3 131.1 96.8 112.6 86.8 59.3 70.7 146.0 241.1 98.3 217.5 85.8 72.7 116.9 165.1 91.3 59.6 135.5 82.6 88.8 160.7 69.1 97.7 92.2 107.0 107.6 160.2 124.1 80.9 138.7 108.6 74.3 65.1 149.1 114.1 99.7 239.2 145.5 81.7 95.4 343.4 245.8 341.1 241.2 298.2 347.5 191.4 325.0 170.8 287.3 312.0 351.8 287.3 553.2 198.2 340.5 88.1 320.8 368.3 289.3 288.0 212.2 174.7 380.0 152.0 428.4 276.9 252.1 230.7 292.6 235.8 249.6 148.9 324.0 400.6 340.1 398.5 203.4 331.6 291.1 390.9 208.0 242.5 355.1 159.3 466.7 181.9 389.8 330.7 250.1 138.0 210.0 257.5 468.5 358.3 289.9 382.3 299.0 342.0 142.3 243.4 420.3 282.2 180.0 314.8 526.5 212.0 275.5 130.0 154.9 280.8 169.0 109.9 347.8 136.4 210.7 136.9 121.6 329.1 204.2 124.8 119.3 138.4 177.5 445.1 146.1 181.5 416.8 62.4 70.0 76.0 90.3 59.3 70.7 85.8 72.7 82.6 80.9 65.1 95.4 101.5 25.6 83.8 31.0 208.1 161.7 131.3 144.8 145.7 37.1 124.5 81.8 76.6 107.2 109.0 57.0 18.8 252.1 148.5 156.6 133.1 185.7 29.5 69.1 138.0 125.4 118.4 177.1 27.7 212.2 312.0 151.5 109.6 84.3 132.5 121.7 121.3 145.9 284.5 92.5 32.1 184.7 91.6 354.2 302.8 40.4 152.2 255.7 149.4 36.5 485.8 75.0 97.9 34.7 49.2 158.1 141.9 141.8 151.3 129.2 271.0 194.1 63.0 36.8 111.7 96.1 125.8 126.2 119.3 177.6 165.1 247.4 120.1 136.9 213.5 131.9 GDPGP1 C15orf58 ENSG00000183208 "GDP-D-glucose phosphorylase 1" Q6ZNW5 15 90233808-90245811 "Enzymes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor, Hydrolase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA048189, HPA059841" Approved Approved Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 1: Pancreatic cells - Digestion" Cytosol "HPA048189: AB_2680307, HPA059841: AB_2684138" "prognostic favorable (6.32e-4)" "unprognostic (1.85e-1)" "unprognostic (2.17e-1)" "unprognostic (2.42e-2)" "unprognostic (2.14e-1)" "unprognostic (1.18e-1)" "unprognostic (1.18e-1)" "unprognostic (2.58e-1)" "unprognostic (3.68e-2)" "unprognostic (4.46e-3)" "unprognostic (1.53e-1)" "unprognostic (3.00e-1)" "unprognostic (1.82e-2)" "unprognostic (2.93e-3)" "unprognostic (8.43e-2)" "unprognostic (1.87e-1)" "unprognostic (1.02e-3)" 1.8 3.2 3.9 3.0 3.0 2.0 2.3 4.3 4.2 2.0 3.1 5.7 5.3 2.2 3.0 2.4 4.6 3.0 5.8 3.2 2.9 4.3 4.9 2.9 3.5 3.7 2.9 2.9 3.5 4.9 3.7 1.0 4.6 3.7 7.7 2.7 3.8 3.1 7.9 2.1 3.9 2.8 1.8 3.2 3.5 4.6 2.9 3.1 3.8 1.5 4.1 3.4 1.5 5.0 3.0 11.8 1.4 4.3 4.3 0.9 3.9 2.7 1.7 3.5 3.3 3.5 11.5 7.5 5.2 2.1 2.6 5.0 4.5 3.2 1.4 6.7 7.8 6.7 7.0 5.1 4.6 3.6 4.2 1.1 2.1 2.4 1.3 3.9 4.2 4.4 2.5 2.6 2.1 6.5 2.7 1.6 1.8 9.2 4.8 4.7 1.0 3.8 4.1 5.9 4.5 2.0 4.3 6.6 4.5 2.6 7.6 3.7 4.2 1.8 1.9 2.7 2.7 5.8 7.3 3.4 4.1 3.0 3.3 3.8 2.2 1.0 3.1 2.6 2.7 2.3 2.9 3.7 2.0 4.2 3.0 2.8 3.1 3.4 2.2 2.1 3.9 1.4 3.9 3.0 4.3 4.2 3.2 2.9 3.7 2.9 4.6 1.8 2.9 5.0 1.4 0.0 3.2 0.3 2.1 0.0 2.8 0.9 1.8 3.8 3.4 2.2 6.4 8.6 1.5 7.3 6.2 2.4 2.5 6.5 3.9 3.8 3.0 3.8 1.6 1.7 5.4 1.7 2.6 6.0 1.2 1.5 4.1 2.3 3.8 2.3 1.4 4.5 4.1 1.7 2.8 3.6 0.0 2.2 0.0 2.4 2.8 3.5 0.0 1.0 2.3 3.5 2.1 1.0 2.1 4.9 5.5 2.2 2.4 2.2 3.8 5.8 3.4 4.4 0.0 3.8 1.0 2.9 2.8 1.8 0.3 0.4 3.2 1.5 4.2 3.1 GID4 "C17orf39, VID24" ENSG00000141034 "GID complex subunit 4 homolog" Q8IVV7 17 18039408-18068405 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 69.1" "Group enriched" "Detected in many" 12 "Early spermatids: 665.5;Late spermatids: 1287.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SuSa: 64.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044348 Uncertain Approved Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 83: Testis - Spermatogenesis" "Cluster 12: NES - Nervous system development" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA044348: AB_10959602" "unprognostic (1.52e-1)" "unprognostic (4.19e-2)" "unprognostic (4.65e-1)" "unprognostic (4.67e-2)" "unprognostic (1.46e-1)" "unprognostic (1.38e-1)" "unprognostic (3.62e-1)" "unprognostic (1.42e-1)" "unprognostic (2.04e-1)" "unprognostic (8.99e-2)" "unprognostic (2.39e-2)" "unprognostic (1.28e-1)" "unprognostic (3.64e-3)" "unprognostic (2.11e-1)" "unprognostic (8.68e-2)" "unprognostic (3.58e-2)" "unprognostic (4.76e-3)" 7.6 5.1 8.3 4.7 7.7 5.8 6.0 9.6 8.6 6.7 5.0 10.0 4.2 7.3 6.5 11.6 6.1 5.1 10.1 7.5 6.6 5.9 5.5 5.3 5.5 7.7 7.6 7.8 7.6 10.5 3.0 6.5 7.7 6.7 4.6 5.7 7.9 7.9 27.7 12.4 4.6 8.5 7.0 5.7 5.8 69.1 7.8 7.2 6.7 14.4 6.0 8.8 7.3 7.7 11.8 12.1 6.7 10.9 17.2 16.8 11.4 9.6 15.6 10.5 11.8 10.2 4.5 14.9 8.1 11.3 9.6 13.1 9.8 10.6 13.7 8.1 19.6 6.6 9.5 7.5 14.9 3.9 11.1 12.5 18.6 10.5 16.3 13.9 11.8 20.9 6.0 4.1 8.6 3.0 12.8 8.4 5.9 14.4 8.8 10.8 23.9 14.8 7.2 4.6 5.0 7.6 6.5 5.7 7.2 64.9 3.6 5.0 10.0 6.7 3.8 15.7 4.9 7.3 6.7 3.2 9.6 6.7 8.8 4.3 1.1 3.6 1.2 0.6 1.3 2.6 1.1 1.2 0.9 2.0 1.3 1.4 2.9 2.0 0.8 1.6 1.9 0.6 8.3 7.7 9.6 8.6 7.5 6.6 7.7 7.6 7.7 7.0 7.8 7.7 8.7 0.0 1.1 5.2 6.0 11.1 7.5 4.5 4.6 5.8 6.4 7.0 12.4 5.7 3.1 1.8 4.2 8.3 6.1 4.1 9.8 5.3 665.5 5.4 9.5 8.4 1.2 17.2 8.2 5.7 15.2 8.0 1.1 5.5 5.7 10.7 8.2 6.8 7.3 16.8 8.1 4.9 0.0 9.5 7.7 1287.8 12.8 7.4 7.2 11.2 9.7 5.4 10.3 9.5 9.8 9.1 1.6 15.8 5.0 16.3 6.9 11.4 3.5 3.9 13.1 8.6 9.0 78.1 26.3 7.2 18.2 15.5 5.9 7.0 4.4 8.0 GIGYF2 "GYF2, KIAA0642, PARK11, PERQ2, PERQ3, TNRC15" ENSG00000204120 "GRB10 interacting GYF protein 2" Q6Y7W6 2 232697299-232860605 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 333.8;Late spermatids: 563.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050899, HPA054612, HPA059918, HPA065064" Approved Enhanced Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 23: Testis - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA050899: AB_2681267, HPA054612: AB_2682542, HPA059918: AB_2684160, HPA065064: AB_2685417" "unprognostic (7.69e-2)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (1.52e-2)" "unprognostic (1.92e-2)" "unprognostic (8.61e-2)" "unprognostic (8.39e-3)" "unprognostic (2.99e-1)" "unprognostic (6.28e-2)" "unprognostic (1.27e-2)" "unprognostic (7.40e-3)" "unprognostic (8.01e-2)" "prognostic favorable (6.97e-5)" "unprognostic (7.53e-2)" "unprognostic (1.78e-1)" "unprognostic (1.20e-2)" "unprognostic (1.66e-1)" 19.1 19.4 13.5 19.1 17.2 21.6 23.1 23.5 14.6 19.0 11.4 17.8 17.6 21.3 13.8 20.4 18.1 15.7 25.6 13.5 18.5 25.2 15.8 16.7 20.4 14.6 13.6 27.4 25.5 40.5 9.6 22.0 15.9 22.0 19.5 22.9 28.4 17.0 37.5 21.2 20.0 18.5 11.4 21.3 21.5 37.9 15.5 24.6 25.9 32.1 21.4 18.6 12.4 21.6 34.3 30.8 37.2 38.1 51.2 44.7 44.1 37.9 36.5 31.3 33.0 30.6 29.6 20.1 9.3 33.5 59.8 36.6 44.2 34.7 41.2 49.4 32.1 71.6 30.5 46.9 36.7 61.3 44.9 31.1 34.6 38.1 59.2 33.6 34.9 33.5 72.8 24.2 33.1 36.5 40.7 24.3 37.5 29.8 25.7 38.7 74.5 27.8 28.6 51.8 33.4 27.5 41.8 30.5 37.7 32.9 29.8 40.1 53.1 33.6 28.6 34.1 29.6 47.6 26.1 40.3 31.6 35.0 31.3 39.2 10.7 13.1 8.0 7.8 10.5 6.1 7.1 7.9 11.2 10.6 8.5 7.9 13.7 13.4 18.9 8.3 10.7 6.4 13.5 17.2 23.5 14.6 13.5 18.5 14.6 13.6 15.9 11.4 15.5 21.6 31.3 57.7 68.4 98.2 26.7 15.7 36.9 25.8 23.9 50.6 29.6 26.0 85.5 25.8 50.8 36.8 60.5 32.2 28.0 28.8 25.4 31.1 333.8 41.2 54.5 36.8 19.2 41.0 105.0 27.3 22.0 36.7 25.0 45.0 17.7 35.4 20.0 28.8 28.5 48.8 131.2 27.9 24.4 29.3 12.1 563.9 37.6 31.8 26.6 98.4 32.9 38.8 42.2 116.6 171.7 29.2 15.0 36.9 39.0 40.6 29.5 18.5 43.3 38.7 26.3 55.0 36.0 128.4 93.4 27.3 19.2 73.2 28.8 46.3 30.3 37.4 GLOD4 "C17orf25, CGI-150, HC71" ENSG00000167699 "Glyoxalase domain containing 4" Q9HC38 17 757097-783390 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021623, HPA023246, HPA023248" Enhanced Approved Cytosol NA NA 3500000 "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA021623: AB_1844365, HPA023246: AB_1844366, HPA023248: AB_1844367" "unprognostic (2.82e-1)" "unprognostic (1.80e-1)" "unprognostic (1.33e-1)" "unprognostic (1.45e-2)" "unprognostic (1.99e-1)" "unprognostic (2.11e-1)" "unprognostic (2.88e-1)" "unprognostic (3.35e-1)" "unprognostic (3.13e-2)" "unprognostic (6.27e-2)" "unprognostic (4.86e-2)" "unprognostic (1.96e-2)" "prognostic favorable (2.18e-6)" "unprognostic (6.21e-3)" "unprognostic (1.33e-1)" "unprognostic (2.46e-1)" "unprognostic (3.02e-1)" 42.5 46.8 27.4 33.5 31.0 22.5 34.5 25.4 33.3 28.4 33.4 71.3 80.5 31.6 33.6 42.9 44.9 32.6 37.3 30.6 36.4 75.7 67.7 31.5 46.9 27.8 27.9 39.9 40.5 37.6 23.2 36.7 28.8 37.8 48.3 25.6 39.5 27.3 39.8 44.3 72.7 31.9 28.3 36.8 85.3 19.4 35.3 35.2 47.4 23.0 40.0 41.5 22.4 27.5 121.1 106.8 120.9 67.1 52.0 51.5 73.8 94.4 57.6 75.0 56.7 87.4 84.0 142.9 100.2 42.8 69.7 85.5 106.6 60.1 78.0 105.4 91.2 69.0 55.7 115.5 51.6 72.1 87.5 36.2 81.9 75.5 66.0 47.7 70.4 116.9 115.1 90.4 80.2 73.9 124.1 55.3 88.7 118.8 36.3 122.7 49.0 65.9 74.5 81.2 54.8 91.8 74.8 53.6 124.6 75.3 66.6 75.2 92.2 71.0 56.8 99.9 120.4 50.3 100.0 89.1 83.6 79.5 75.9 26.1 51.8 48.7 68.1 64.1 73.2 70.0 81.0 82.2 45.9 75.4 68.9 75.7 7.1 64.0 70.4 47.2 99.1 75.9 27.4 31.0 25.4 33.3 30.6 36.4 27.8 27.9 28.8 28.3 35.3 27.5 52.2 57.7 35.2 11.4 48.5 47.9 40.4 91.1 40.5 39.6 39.2 36.3 30.9 54.3 70.4 101.2 29.2 104.5 43.2 39.3 178.1 77.3 34.0 44.0 34.3 43.8 28.9 54.7 12.7 57.4 85.9 41.5 71.4 40.8 40.4 42.1 31.1 58.8 82.3 13.5 13.6 52.0 97.6 30.1 26.5 63.3 38.8 40.8 67.6 7.5 61.7 39.8 44.3 10.1 13.2 58.7 52.0 46.6 27.5 39.4 110.5 186.1 66.8 38.7 46.0 30.3 45.8 23.5 32.9 53.6 54.8 69.1 53.3 57.2 63.7 39.3 GLT1D1 FLJ31978 ENSG00000151948 "Glycosyltransferase 1 domain containing 1" Q96MS3 12 128853427-128984968 "Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.1;liver: 27.6" "Cell type enhanced" "Detected in some" "Early spermatids: 14.6;Excitatory neurons: 37.6;Inhibitory neurons: 30.2;Late spermatids: 41.7;Oligodendrocyte precursor cells: 34.7" "Group enriched" "Detected in some" 6 "liver cancer: 6.2;testis cancer: 2.6;thyroid cancer: 4.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 36.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 36.4" "Group enriched" "Detected in some" 7 "MOLT-4: 13.0;NTERA-2: 17.9;SCLC-21H: 8.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039051, HPA039052" Enhanced Cytosol "Secreted to blood" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "HPA039051: AB_10673299, HPA039052: AB_10672839" "unprognostic (1.49e-1)" "unprognostic (9.85e-2)" "unprognostic (1.11e-1)" "unprognostic (1.26e-1)" "unprognostic (3.60e-2)" "unprognostic (3.47e-3)" "unprognostic (2.88e-1)" "unprognostic (2.53e-1)" "unprognostic (4.04e-1)" "unprognostic (1.81e-1)" "unprognostic (1.24e-2)" "unprognostic (1.05e-1)" "unprognostic (3.93e-5)" "unprognostic (2.39e-2)" "unprognostic (2.20e-1)" "unprognostic (1.55e-3)" "unprognostic (2.41e-1)" 2.5 0.2 7.0 6.8 7.3 28.1 0.2 1.5 9.8 2.4 5.6 0.4 0.1 3.6 1.0 0.5 3.0 1.7 0.8 7.1 11.1 0.8 27.6 2.8 0.3 2.9 2.6 0.2 0.8 0.6 1.4 0.7 3.1 0.8 0.3 5.7 0.2 1.5 9.0 1.1 0.3 3.1 1.2 12.7 0.3 15.5 4.3 0.9 1.7 9.6 0.4 1.4 0.5 6.8 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 17.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.3 0.0 0.0 0.0 1.9 0.0 0.3 0.0 0.0 1.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.5 3.6 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 36.4 0.0 2.0 2.3 0.0 1.6 7.0 7.3 1.5 9.8 7.1 11.1 2.9 2.6 3.1 1.2 4.3 6.8 0.0 0.0 0.0 1.6 0.4 0.9 0.0 0.0 0.0 0.8 0.0 0.5 0.4 0.0 0.0 0.0 2.1 0.0 4.7 0.0 0.0 0.1 14.6 0.6 2.3 0.1 0.0 0.0 37.6 0.0 0.0 0.4 0.0 4.8 0.0 0.1 1.1 10.4 1.4 0.0 30.2 0.0 0.0 8.5 0.0 41.7 0.3 9.4 1.8 6.5 12.4 10.4 1.0 34.7 1.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 1.3 0.0 0.2 0.2 4.0 0.6 0.0 0.3 0.1 0.2 0.0 0.0 0.0 GLTP ENSG00000139433 "Glycolipid transfer protein" Q9NZD2 12 109850945-109880541 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 334.1;skin 1: 276.6" "Cell type enhanced" "Detected in all" "Squamous epithelial cells: 266.5;Suprabasal keratinocytes: 479.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056461, HPA065503" Approved Supported Cytosol NA NA 25000 "Cluster 7: Monocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA056461: AB_2683138, HPA065503: " "unprognostic (1.18e-1)" "prognostic favorable (2.01e-5)" "unprognostic (7.46e-2)" "unprognostic (6.22e-3)" "unprognostic (1.95e-1)" "unprognostic (3.73e-2)" "prognostic unfavorable (7.68e-4)" "unprognostic (6.63e-2)" "unprognostic (1.56e-1)" "unprognostic (1.62e-1)" "unprognostic (2.47e-1)" "unprognostic (3.03e-1)" "unprognostic (4.83e-2)" "unprognostic (4.46e-2)" "unprognostic (2.20e-1)" "prognostic favorable (4.17e-6)" "unprognostic (3.28e-2)" 19.0 21.7 59.1 17.5 98.8 19.3 27.1 93.6 75.1 94.4 43.1 38.4 14.6 15.9 34.8 334.1 13.6 14.2 21.0 62.3 69.9 53.2 15.1 24.4 19.3 110.3 89.5 18.2 23.8 31.4 12.5 17.8 102.5 29.4 31.8 7.0 84.7 19.1 18.6 276.6 32.1 18.8 84.0 21.5 21.6 16.3 87.3 18.0 23.5 18.1 108.2 33.6 178.0 138.5 39.3 27.9 15.5 16.7 36.2 41.4 11.0 47.4 58.2 36.0 29.7 11.3 14.9 34.5 25.3 57.8 17.5 47.3 24.2 54.9 50.7 35.0 21.5 22.6 15.9 16.5 31.6 24.6 25.5 30.1 68.8 64.6 45.3 53.9 61.3 34.8 10.1 22.5 53.2 52.9 33.6 19.8 28.1 32.0 36.8 29.3 36.4 36.3 20.5 116.1 20.0 19.8 30.1 77.1 26.0 14.1 36.1 8.6 83.2 41.4 21.9 61.5 36.5 30.1 27.7 23.8 83.0 25.1 25.9 42.6 65.7 37.3 51.5 66.0 32.4 23.9 31.0 46.5 48.8 21.5 20.1 35.8 32.9 42.4 57.0 8.0 37.6 40.6 59.1 98.8 93.6 75.1 62.3 69.9 110.3 89.5 102.5 84.0 87.3 138.5 48.1 25.6 60.9 10.4 37.5 145.4 109.1 72.1 88.2 11.4 55.6 44.4 14.6 18.6 62.7 44.1 14.6 86.5 48.3 95.6 199.6 39.0 20.5 30.1 33.3 47.9 32.4 10.1 9.9 56.5 20.0 35.0 28.5 59.1 20.8 19.0 34.2 15.3 34.5 13.5 11.4 39.2 50.8 61.6 84.6 11.7 23.0 55.3 60.5 13.1 61.8 23.4 64.9 21.6 140.1 53.5 40.0 18.0 26.2 80.6 102.3 38.2 25.2 12.3 39.5 23.5 37.3 22.9 20.8 266.5 479.2 210.6 46.3 31.4 59.1 129.0 GMPS GATD7 ENSG00000163655 "Guanine monophosphate synthase" P49915 3 155870650-155944020 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "GMP biosynthesis, Purine biosynthesis" Ligase Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 100.3" "Cell type enhanced" "Detected in all" "Early spermatids: 272.7;Late spermatids: 193.6;Spermatocytes: 171.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046630 Approved Cytosol No No 50000 "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA046630: AB_2679727" "unprognostic (3.89e-2)" "unprognostic (2.02e-2)" "unprognostic (1.59e-2)" "prognostic unfavorable (5.54e-5)" "unprognostic (2.30e-1)" "unprognostic (1.35e-2)" "prognostic unfavorable (8.73e-7)" "unprognostic (1.71e-2)" "unprognostic (3.52e-2)" "unprognostic (1.77e-2)" "prognostic unfavorable (1.04e-4)" "unprognostic (2.58e-2)" "unprognostic (2.79e-2)" "unprognostic (2.89e-2)" "unprognostic (3.78e-1)" "unprognostic (3.55e-3)" "unprognostic (8.79e-2)" 18.8 20.7 7.2 20.0 7.7 44.6 24.1 22.7 11.0 21.2 7.9 19.7 15.8 20.6 16.0 22.1 17.1 14.0 17.9 6.8 8.5 15.9 22.6 18.2 27.0 7.8 6.8 17.0 26.4 23.1 11.5 20.8 8.3 17.4 22.5 10.1 20.9 17.5 20.0 25.0 16.7 23.4 6.3 19.2 18.0 100.3 8.0 32.3 20.3 16.7 29.4 23.3 19.9 8.8 241.0 93.1 123.0 101.1 49.0 77.0 118.9 99.8 91.6 128.2 128.8 170.5 156.2 171.7 116.1 77.1 98.1 114.6 105.7 104.2 175.0 101.1 81.8 183.2 63.7 92.8 55.9 188.5 68.7 57.3 62.9 99.4 150.5 68.2 79.9 91.3 131.7 63.8 96.8 160.1 153.9 99.4 118.5 130.4 68.3 149.2 145.8 207.5 66.3 103.5 73.3 68.0 111.0 156.0 101.8 83.9 163.6 122.3 56.9 84.4 68.5 121.0 204.3 88.8 58.5 288.5 84.8 137.4 77.0 23.7 16.1 11.5 24.7 20.2 29.1 16.0 23.6 22.3 26.1 11.6 23.3 22.3 2.2 29.3 29.5 14.2 27.1 17.5 7.2 7.7 22.7 11.0 6.8 8.5 7.8 6.8 8.3 6.3 8.0 8.8 23.8 19.2 20.2 19.6 21.5 39.9 47.4 43.9 22.8 22.0 19.5 18.5 16.4 15.7 28.4 7.3 2.1 44.1 21.6 8.3 25.4 33.8 272.7 14.3 37.5 29.9 7.2 68.5 40.9 29.5 56.2 32.4 19.9 18.4 28.6 34.0 22.1 11.6 29.9 21.9 41.6 19.7 26.4 18.5 27.1 193.6 23.0 25.2 23.2 22.5 31.7 17.8 30.9 30.2 31.6 21.3 11.9 24.8 21.9 50.6 17.8 22.8 17.3 8.7 19.7 28.6 65.2 171.2 65.5 29.0 38.2 30.8 30.4 63.2 26.8 42.4 GNA12 gep ENSG00000146535 "G protein subunit alpha 12" Q03113 7 2728105-2844308 "Human disease related genes, Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 53.2" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 68.3;Syncytiotrophoblasts: 173.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010046 Approved Supported Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 70: Brain - Nervous system development" "Cluster 44: HDLM-2 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "CAB010046: AB_2263416" "unprognostic (1.21e-1)" "unprognostic (1.19e-2)" "unprognostic (9.28e-2)" "unprognostic (1.54e-1)" "unprognostic (2.14e-2)" "unprognostic (1.27e-3)" "prognostic unfavorable (1.20e-6)" "unprognostic (1.38e-2)" "unprognostic (1.48e-1)" "unprognostic (1.36e-2)" "unprognostic (4.45e-3)" "unprognostic (7.90e-2)" "prognostic unfavorable (4.71e-5)" "unprognostic (1.22e-2)" "unprognostic (2.52e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (2.27e-4)" 17.8 14.9 42.5 11.2 47.1 11.0 12.2 38.4 35.8 12.9 18.3 16.6 5.1 17.0 4.7 7.7 12.9 9.4 17.9 36.1 39.6 8.6 9.3 12.8 12.8 53.2 43.9 18.2 11.9 8.0 12.3 24.4 42.5 9.5 6.1 3.0 8.0 11.4 6.7 5.0 11.3 13.6 46.2 10.6 11.6 10.1 52.6 5.6 6.7 7.3 10.1 16.6 9.2 42.3 35.5 19.1 19.4 29.2 30.4 24.1 53.5 29.1 33.7 30.9 35.3 18.4 24.5 7.5 19.4 34.6 64.7 15.6 13.5 30.1 20.9 89.9 13.5 15.3 9.9 19.6 35.4 2.5 13.1 23.5 16.1 36.3 24.4 31.8 33.3 10.6 17.3 23.0 28.1 16.8 4.1 14.1 27.3 9.1 32.9 26.8 22.4 15.2 11.4 23.8 15.4 22.3 16.4 24.4 12.2 27.6 13.6 20.9 39.5 33.6 39.9 33.2 48.6 16.1 20.3 6.8 36.1 22.5 33.7 1.4 0.5 0.1 0.2 1.3 0.3 1.0 0.5 0.3 0.4 1.7 0.5 0.0 0.1 0.0 0.3 1.8 0.7 0.4 42.5 47.1 38.4 35.8 36.1 39.6 53.2 43.9 42.5 46.2 52.6 42.3 21.8 6.4 11.7 41.8 22.0 7.0 3.8 5.4 0.6 6.0 14.5 10.4 16.3 10.0 6.1 1.8 12.5 63.7 16.6 8.0 3.9 7.9 13.3 9.3 21.8 16.7 7.8 9.5 31.9 10.2 17.0 19.6 10.2 10.8 0.0 13.9 19.2 13.5 25.4 8.4 36.0 5.5 6.1 21.6 63.5 13.6 17.1 25.8 21.4 22.5 21.7 16.1 7.2 68.3 29.9 13.2 4.0 18.8 7.3 8.4 4.7 7.1 5.8 10.7 0.0 16.8 17.3 8.6 9.4 1.2 3.7 173.2 6.2 23.7 5.3 3.2 GNA13 "G13, MGC46138" ENSG00000120063 "G protein subunit alpha 13" Q14344 17 65009289-65056740 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Transducer "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 144.5" "Cell type enriched" "Detected in all" 4 "Langerhans cells: 537.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010087 Approved Supported Cytosol NA NA 320000 "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Cytosol "HPA010087: AB_10601478" "unprognostic (2.55e-1)" "unprognostic (2.27e-1)" "unprognostic (1.33e-3)" "unprognostic (1.23e-3)" "unprognostic (8.21e-2)" "unprognostic (7.05e-2)" "unprognostic (4.22e-3)" "unprognostic (1.09e-1)" "unprognostic (7.77e-2)" "unprognostic (4.66e-1)" "unprognostic (1.16e-2)" "unprognostic (1.94e-1)" "unprognostic (1.18e-1)" "unprognostic (1.18e-1)" "unprognostic (1.21e-1)" "unprognostic (1.44e-1)" "unprognostic (1.59e-1)" 23.7 22.5 21.3 41.5 23.9 144.5 15.8 25.0 22.5 17.6 21.3 27.7 21.0 17.9 10.5 18.2 15.9 26.5 12.6 20.2 26.6 17.6 27.0 27.1 46.8 26.9 21.7 22.6 15.3 15.8 8.3 39.3 30.1 15.1 26.2 17.2 10.4 16.1 36.8 12.1 23.3 22.9 25.4 33.5 18.0 15.4 23.7 49.9 17.9 38.6 44.6 30.5 12.3 35.2 33.3 36.9 32.6 21.6 31.8 29.5 32.2 25.3 28.7 35.0 39.7 20.7 23.0 130.0 16.1 26.6 42.0 22.5 35.0 29.4 51.5 35.4 19.5 69.0 20.7 38.7 45.7 54.2 45.5 23.9 43.8 32.2 42.0 29.1 48.6 33.6 29.7 82.3 36.9 29.3 88.9 18.8 19.4 30.2 25.7 49.0 64.8 47.2 32.0 53.3 24.5 48.8 19.7 34.8 43.8 62.1 40.7 50.0 37.9 58.4 48.8 25.0 33.2 57.3 79.4 151.4 20.1 32.2 30.4 7.3 6.0 7.6 5.6 12.5 5.7 4.5 6.8 6.8 5.2 4.0 3.9 4.4 13.8 6.8 8.5 2.1 9.7 4.0 21.3 23.9 25.0 22.5 20.2 26.6 26.9 21.7 30.1 25.4 23.7 35.2 34.5 12.8 13.0 68.9 80.9 67.8 27.8 13.1 42.1 5.3 21.0 13.0 11.7 18.6 10.1 9.2 4.2 16.6 60.5 82.2 7.9 11.8 4.5 25.3 23.6 35.4 16.8 21.2 20.7 11.6 15.1 24.3 23.9 49.9 30.4 21.9 32.5 13.8 57.4 6.7 27.3 11.6 12.2 57.9 537.6 8.0 11.5 123.8 69.4 44.0 44.1 34.4 29.9 29.1 36.7 13.4 30.7 24.0 45.9 28.3 23.5 16.4 13.8 6.1 32.9 19.2 19.9 6.7 13.6 33.7 65.9 14.0 66.5 15.4 13.7 36.2 GNB1L "GY2, WDR14" ENSG00000185838 "G protein subunit beta 1 like" Q9BYB4 22 19783223-19854939 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "K-562: 66.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034627, HPA034628" Approved Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "HPA034627: AB_10600662, HPA034628: AB_10600440" "unprognostic (2.14e-1)" "unprognostic (5.56e-3)" "unprognostic (4.54e-3)" "unprognostic (2.58e-1)" "unprognostic (3.03e-1)" "unprognostic (3.34e-2)" "unprognostic (8.68e-4)" "unprognostic (1.09e-1)" "unprognostic (1.19e-1)" "unprognostic (4.26e-1)" "unprognostic (2.46e-1)" "unprognostic (2.99e-2)" "unprognostic (3.64e-5)" "unprognostic (9.80e-3)" "unprognostic (8.04e-2)" "unprognostic (2.88e-1)" "unprognostic (9.86e-2)" 3.5 2.2 1.4 2.8 1.8 1.7 3.5 1.0 3.7 3.8 0.6 4.0 4.1 4.1 0.4 4.9 3.9 1.0 2.7 1.8 0.8 2.6 2.8 3.1 2.3 1.3 0.7 3.5 3.9 0.4 2.2 1.4 0.9 3.4 0.3 0.3 3.3 1.3 3.7 5.9 3.7 0.6 0.6 5.3 2.7 2.4 0.9 4.0 3.0 0.6 1.3 4.2 4.2 1.3 13.5 10.2 2.9 8.9 0.9 1.7 8.0 9.1 2.5 4.4 4.1 18.3 5.2 18.1 5.8 2.1 2.1 25.5 2.0 4.3 0.6 11.7 34.0 10.9 13.6 9.1 2.7 12.6 2.9 1.4 2.0 3.9 1.5 1.0 1.7 8.1 66.6 6.8 0.8 19.3 28.1 18.1 5.0 3.9 17.1 14.6 8.1 4.1 0.4 5.4 5.9 6.4 3.5 8.8 15.5 0.5 2.3 3.2 4.2 9.8 11.8 16.1 9.3 8.8 7.8 9.6 10.6 11.1 3.4 7.3 6.0 15.9 13.2 7.9 12.7 9.4 12.6 10.0 9.8 11.9 12.1 11.0 6.1 12.0 5.9 13.3 17.0 7.5 1.4 1.8 1.0 3.7 1.8 0.8 1.3 0.7 0.9 0.6 0.9 1.3 2.4 3.2 4.4 3.6 6.9 22.0 6.3 11.8 5.2 8.5 4.7 5.5 1.6 2.8 5.7 0.0 12.5 15.2 5.2 4.6 3.9 5.6 28.3 2.9 3.3 4.6 0.0 4.0 6.7 3.3 13.8 4.3 2.0 4.1 12.7 7.8 2.2 2.8 10.3 0.0 4.1 4.6 8.2 7.3 15.5 6.5 3.4 4.6 14.2 1.9 4.9 3.0 6.2 4.5 4.3 5.9 2.6 4.9 5.4 8.8 6.3 4.9 1.9 4.7 6.6 2.8 4.4 13.8 10.2 5.1 16.2 4.7 7.9 2.7 5.2 5.3 GNE "IBM2, Uae1" ENSG00000159921 "Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase" Q9Y223 9 36214441-36277042 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Allosteric enzyme, Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "intestine: 48.4;liver: 90.5;salivary gland: 55.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 59.3;Hepatocytes: 119.3;Intestinal goblet cells: 88.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 107.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007045, HPA027258" Approved Supported Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol "HPA007045: AB_1079003, HPA027258: AB_1849873" "unprognostic (7.54e-2)" "unprognostic (1.61e-2)" "unprognostic (1.07e-3)" "unprognostic (7.28e-2)" "unprognostic (7.00e-2)" "unprognostic (1.85e-2)" "unprognostic (2.78e-3)" "unprognostic (5.39e-2)" "unprognostic (1.73e-1)" "unprognostic (1.70e-2)" "unprognostic (2.88e-3)" "unprognostic (4.20e-2)" "prognostic favorable (9.28e-11)" "unprognostic (2.90e-1)" "unprognostic (8.28e-2)" "unprognostic (2.95e-1)" "unprognostic (1.72e-2)" 11.9 9.0 5.5 8.7 7.4 15.5 15.8 8.9 6.5 11.3 7.9 34.0 4.3 10.3 3.5 11.6 9.1 7.4 7.7 5.5 7.3 10.0 90.5 6.8 7.3 7.7 7.3 14.8 10.2 6.1 4.8 14.2 8.9 15.3 48.4 8.0 55.3 7.2 7.9 3.8 7.6 11.7 6.6 6.2 4.6 4.8 7.1 6.2 6.9 15.3 9.5 14.2 7.5 10.5 9.9 44.4 20.1 17.1 22.5 22.4 29.9 13.5 17.9 19.5 25.1 10.5 32.6 13.5 14.2 24.2 50.5 3.9 15.3 4.6 21.8 25.1 1.4 11.0 26.0 15.2 15.4 0.2 31.2 14.4 4.6 32.0 30.6 14.3 8.4 20.7 14.4 27.3 19.3 1.8 19.1 6.3 11.8 6.7 23.7 15.5 16.3 3.8 107.7 19.4 16.7 15.2 13.7 5.3 12.6 7.1 4.8 12.0 12.2 12.7 12.9 15.5 12.2 11.7 26.0 7.0 17.0 9.8 18.2 0.2 0.5 0.2 0.7 0.6 0.5 0.6 0.9 0.8 0.4 0.9 1.0 1.2 0.3 0.7 0.8 0.6 0.4 0.6 5.5 7.4 8.9 6.5 5.5 7.3 7.7 7.3 8.9 6.6 7.1 10.5 9.7 9.6 10.0 9.4 7.1 1.9 3.1 6.7 1.8 8.4 8.2 7.5 6.7 10.0 16.9 9.2 6.2 8.6 4.3 59.3 1.9 10.4 3.4 7.2 12.1 6.3 11.5 7.8 12.8 6.0 9.5 8.3 2.6 10.6 10.1 9.1 7.1 119.3 2.9 11.8 15.6 88.1 16.2 7.8 4.4 2.4 10.8 5.4 1.8 5.6 6.1 1.9 2.1 32.2 28.2 5.3 20.3 6.4 7.9 6.9 2.9 2.2 18.8 6.9 13.1 10.0 6.3 1.8 2.7 1.2 1.6 19.8 5.7 2.3 26.8 13.4 GNMT ENSG00000124713 "Glycine N-methyltransferase" Q14749 6 42960754-42963880 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "liver: 296.5;pancreas: 600.1" "Cell type enriched" "Detected in many" 10 "Hepatocytes: 842.9" "Group enriched" "Detected in many" 20 "liver cancer: 69.6;prostate cancer: 49.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 8.5;SCLC-21H: 9.5;T-47d: 6.1" "Region enriched" "Detected in some" 4 "cerebellum: 15.7" "Low region specificity" "Detected in many" HPA027501 Enhanced Approved Cytosol NA NA 390000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Cytosol "HPA027501: AB_1849879" "unprognostic (1.53e-2)" "unprognostic (8.02e-4)" "unprognostic (3.11e-2)" "unprognostic (4.24e-3)" "unprognostic (3.91e-2)" "unprognostic (6.40e-4)" "prognostic favorable (1.86e-4)" "unprognostic (4.08e-6)" "unprognostic (1.01e-1)" "unprognostic (2.67e-2)" "unprognostic (1.63e-3)" "unprognostic (2.52e-1)" "unprognostic (3.50e-3)" "unprognostic (1.03e-1)" "unprognostic (1.99e-1)" "unprognostic (2.49e-2)" "unprognostic (4.92e-2)" 0.9 0.9 2.3 1.3 2.5 3.8 7.1 2.8 2.4 0.8 2.0 0.7 0.2 0.8 2.2 0.6 1.3 0.5 4.7 2.2 2.2 0.9 296.5 2.0 1.0 1.1 1.0 1.9 600.1 0.2 8.4 0.4 1.1 20.3 0.3 2.2 9.8 1.2 1.8 0.9 1.6 0.5 0.9 2.9 50.8 0.7 1.9 1.8 1.9 0.4 1.2 0.8 0.7 2.1 0.4 0.3 1.4 3.9 0.4 0.1 0.2 0.3 1.6 0.6 0.9 0.0 0.1 1.3 0.1 0.3 0.7 0.4 0.2 0.2 0.2 1.6 1.2 1.0 0.9 8.5 0.0 0.9 1.8 0.3 0.0 0.3 0.1 0.9 0.0 3.0 1.2 1.5 0.2 1.8 1.6 3.0 0.1 0.4 0.4 1.4 1.3 0.8 0.6 0.2 9.5 1.3 0.1 1.3 0.6 0.4 6.1 2.8 0.3 0.7 0.7 0.4 0.8 1.0 1.0 1.1 0.1 1.6 0.8 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.2 0.5 0.0 0.0 0.7 0.0 0.1 2.3 2.5 2.8 2.4 2.2 2.2 1.1 1.0 1.1 0.9 1.9 2.1 0.3 0.0 2.2 5.5 2.8 0.3 5.2 0.7 0.0 1.7 10.2 14.7 5.4 24.3 0.2 1.8 0.0 0.1 1.7 0.0 3.9 0.5 0.2 1.6 0.2 2.2 0.0 77.9 18.4 0.9 0.1 0.3 0.5 0.8 0.0 2.6 24.3 842.9 0.7 1.7 18.2 0.0 6.1 28.9 0.7 0.1 0.9 1.1 0.0 11.2 0.3 0.2 0.0 7.1 4.7 0.6 0.0 2.6 0.5 17.9 0.3 3.4 4.6 0.3 0.0 0.2 0.6 0.6 0.7 0.0 0.1 0.1 3.0 0.0 0.2 1.9 GP5 CD42d ENSG00000178732 "Glycoprotein V platelet" P40197 3 194394821-194398354 "CD markers, Plasma proteins, Predicted membrane proteins" "Blood coagulation, Cell adhesion, Hemostasis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.1" "Cell type enhanced" "Detected in single" "Paneth cells: 1.1" "Cancer enriched" "Detected in single" 5 "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "HEL: 16.3" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA072646 Approved Cytosol NA NA 270000000 "Cluster 32: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 36: HEL - Hemostasis" "Cluster 58: T-cells - T-cell receptor" Cytosol "HPA072646: " "unprognostic (3.74e-2)" "unprognostic (3.40e-1)" "unprognostic (5.22e-2)" "unprognostic (2.96e-2)" "unprognostic (1.74e-2)" "unprognostic (1.35e-3)" "unprognostic (1.69e-3)" "unprognostic (1.68e-1)" "unprognostic (3.41e-1)" "unprognostic (2.80e-2)" "unprognostic (1.65e-1)" "unprognostic (5.51e-2)" "unprognostic (1.21e-2)" "unprognostic (4.18e-2)" "unprognostic (3.14e-1)" "unprognostic (1.72e-2)" "unprognostic (1.94e-1)" 0.1 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.0 0.1 0.0 0.1 0.1 1.1 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.1 0.3 0.2 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 GPR34 ENSG00000171659 "G protein-coupled receptor 34" Q9UPC5 X 41688973-41697275 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 42.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 251.4;Kupffer cells: 173.3;Macrophages: 100.6;Microglial cells: 54.4" "Cancer enhanced" "Detected in all" "glioma: 26.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "basophil: 339.6;eosinophil: 117.9" "Lineage enriched" "Detected in many" 24 "granulocytes: 339.6" "Cell line enhanced" "Detected in single" "HMC-1: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010668, CAB025490" Uncertain Approved Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB025490: , HPA010668: AB_1849294" "unprognostic (1.26e-2)" "unprognostic (1.08e-1)" "unprognostic (1.43e-2)" "unprognostic (1.44e-2)" "unprognostic (1.20e-1)" "unprognostic (3.74e-2)" "unprognostic (5.83e-3)" "unprognostic (5.13e-2)" "unprognostic (1.59e-2)" "unprognostic (9.81e-3)" "unprognostic (7.19e-2)" "unprognostic (1.74e-1)" "unprognostic (3.96e-1)" "unprognostic (2.72e-3)" "unprognostic (1.14e-1)" "unprognostic (1.88e-3)" "unprognostic (3.18e-2)" 28.2 17.1 5.2 15.1 5.2 0.9 21.5 6.1 5.8 14.0 5.6 12.0 6.5 6.7 2.7 8.2 7.8 17.0 8.3 5.0 7.6 5.0 8.5 10.9 20.0 10.6 7.9 7.3 5.4 5.3 1.4 42.7 11.4 3.2 13.1 0.6 3.6 8.8 0.8 1.0 14.6 16.3 9.9 15.6 7.8 2.7 9.7 6.9 3.7 4.6 16.7 13.3 1.7 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 339.6 9.7 117.9 0.0 12.9 0.4 1.5 0.4 0.1 2.0 1.2 0.1 0.3 1.1 14.3 7.0 0.3 0.6 2.8 5.2 5.2 6.1 5.8 5.0 7.6 10.6 7.9 11.4 9.9 9.7 18.8 0.9 0.0 2.8 1.0 2.0 0.6 0.2 0.0 0.0 0.0 0.5 2.3 1.2 0.0 0.0 0.0 0.0 1.4 0.4 0.0 0.0 0.0 0.6 0.1 0.1 5.0 1.2 0.4 0.7 0.0 1.6 1.0 0.5 0.0 37.3 0.0 2.9 0.8 251.4 0.0 0.9 0.0 0.0 173.3 13.6 1.9 0.9 100.6 1.8 54.4 7.1 0.1 1.0 3.5 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.1 0.0 0.8 19.7 0.6 0.3 0.0 0.2 0.4 1.0 2.5 7.2 0.1 0.1 0.0 GPRASP1 "GASP, GASP1" ENSG00000198932 "G protein-coupled receptor associated sorting protein 1" Q5JY77 X 102651092-102659083 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 42.6;Cardiomyocytes: 28.6;Cone photoreceptor cells: 37.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 4.5;REH: 5.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000161, HPA031061" Approved Supported Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA000161: AB_2247872, HPA031061: AB_2673718" "unprognostic (3.92e-3)" "unprognostic (1.10e-1)" "unprognostic (2.07e-4)" "unprognostic (1.42e-1)" "unprognostic (3.32e-2)" "unprognostic (1.71e-3)" "unprognostic (3.57e-1)" "unprognostic (2.33e-2)" "unprognostic (1.58e-1)" "unprognostic (2.82e-1)" "prognostic favorable (1.77e-5)" "unprognostic (3.34e-1)" "unprognostic (2.48e-1)" "unprognostic (1.93e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (7.38e-4)" "unprognostic (1.23e-2)" 8.6 22.6 25.1 5.4 23.9 3.8 9.9 19.8 31.2 32.4 2.7 23.3 2.4 25.5 10.7 4.4 26.7 7.6 17.7 22.8 33.2 10.3 2.9 7.2 9.4 16.6 17.8 53.4 5.6 17.3 43.5 2.9 18.6 20.4 4.5 29.9 8.7 17.7 6.1 5.2 12.4 15.3 12.8 11.3 9.6 5.3 23.6 6.8 26.1 4.2 7.6 18.6 16.9 20.2 0.2 0.5 1.7 1.1 1.7 1.7 1.0 1.8 0.1 2.7 4.5 0.2 0.3 0.0 0.4 3.8 0.3 0.5 0.5 0.1 3.9 0.0 0.2 0.1 0.6 0.5 1.4 0.2 0.2 2.2 0.7 3.3 0.3 0.4 0.2 1.8 0.3 0.1 4.3 0.4 3.7 0.1 1.2 0.3 0.6 5.6 1.7 0.0 0.2 0.4 1.7 2.7 0.6 0.2 0.5 1.4 0.2 0.9 0.5 0.8 1.0 0.5 0.3 0.3 0.5 0.0 0.4 0.2 1.1 0.0 0.0 0.0 0.5 0.0 1.3 0.2 1.1 0.4 0.0 0.7 2.3 2.3 0.0 0.1 0.0 0.3 0.8 0.5 25.1 23.9 19.8 31.2 22.8 33.2 16.6 17.8 18.6 12.8 23.6 20.2 5.1 0.0 3.6 0.0 4.4 3.6 4.1 0.8 1.8 42.6 1.8 3.0 28.6 1.5 3.5 5.5 37.5 0.4 3.5 0.1 0.0 0.2 0.3 0.6 6.5 7.3 6.0 0.4 0.0 0.2 0.2 9.9 1.1 0.7 2.5 13.9 7.1 0.7 0.3 6.7 0.0 0.7 0.0 0.3 2.0 1.7 15.2 1.3 1.8 0.0 0.5 12.9 3.1 0.0 0.0 0.6 0.1 15.4 2.2 3.8 0.4 1.7 1.2 18.8 6.6 16.9 8.5 7.0 2.4 0.4 0.9 0.1 7.3 6.5 0.8 1.6 GPSM2 "DFNB82, LGN, Pins" ENSG00000121957 "G protein signaling modulator 2" P81274 1 108875350-108934545 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis, Transport" Deafness "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 46.9;tongue: 54.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 133.5;Oligodendrocyte precursor cells: 134.7;Oligodendrocytes: 127.4;Syncytiotrophoblasts: 89.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 3.2;T-reg: 1.8" "Group enriched" "Detected in many" 5 "granulocytes: 3.2;T-cells: 1.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007327, HPA008408, CAB018962" Uncertain Supported Cytosol NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "CAB018962: , HPA007327: AB_1849941, HPA008408: AB_1849939" "unprognostic (1.97e-1)" "unprognostic (6.80e-2)" "prognostic favorable (7.86e-5)" "unprognostic (1.37e-3)" "unprognostic (3.18e-2)" "unprognostic (1.97e-2)" "unprognostic (8.57e-6)" "unprognostic (7.12e-2)" "unprognostic (2.76e-2)" "unprognostic (3.92e-2)" "prognostic unfavorable (5.89e-4)" "unprognostic (7.55e-3)" "prognostic unfavorable (3.02e-4)" "unprognostic (6.27e-3)" "unprognostic (1.00e-1)" "unprognostic (5.14e-3)" "unprognostic (6.00e-2)" 5.3 3.5 27.3 4.4 39.5 14.4 7.5 33.8 25.2 12.6 10.8 15.3 9.1 6.8 2.6 34.1 4.2 2.6 4.3 23.3 29.5 2.3 2.9 9.0 6.4 33.9 36.3 3.3 3.6 9.7 3.1 7.7 33.9 5.9 15.2 8.6 10.1 4.7 10.7 37.7 11.5 10.5 32.1 2.7 5.1 11.5 34.1 18.4 3.2 54.4 13.2 6.0 17.7 46.9 135.6 16.2 36.8 27.7 36.4 20.2 30.0 24.2 61.4 29.9 45.4 16.0 31.7 30.5 6.7 33.4 21.0 28.3 25.3 59.1 39.6 30.7 15.8 19.8 34.7 16.5 4.8 28.6 18.5 4.1 113.9 29.4 129.8 9.4 26.9 19.5 14.9 42.3 58.4 37.8 26.1 12.2 8.7 52.1 29.4 20.1 66.7 6.6 24.3 18.6 30.4 26.9 37.0 69.2 26.9 10.3 27.6 24.3 18.0 21.7 36.7 64.8 48.5 18.4 20.9 28.6 34.3 47.4 108.9 0.1 0.3 3.2 0.2 0.3 0.1 0.2 0.2 0.2 0.3 0.4 0.4 0.3 0.3 0.1 0.1 0.1 1.8 0.1 27.3 39.5 33.8 25.2 23.3 29.5 33.9 36.3 33.9 32.1 34.1 46.9 4.6 16.0 3.3 63.0 5.7 62.7 18.8 12.9 47.3 47.7 3.0 3.7 2.5 2.8 12.5 7.3 133.5 46.3 6.7 10.8 11.7 2.5 54.0 5.2 20.6 5.1 9.1 33.9 11.7 1.9 47.7 19.5 8.6 9.2 2.5 14.4 2.9 1.6 9.0 43.7 24.0 14.1 10.2 5.3 11.3 21.3 18.6 4.9 26.6 3.7 5.3 8.0 2.1 134.7 127.4 4.8 7.8 5.3 5.3 5.6 8.4 0.9 9.0 48.1 0.0 43.6 6.9 20.6 28.9 24.0 40.6 89.2 7.1 10.0 18.7 15.5 GPX1 ENSG00000233276 "Glutathione peroxidase 1" P07203 3 49357176-49358353 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3273.8;Kupffer cells: 3971.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 1534.3;granulocytes: 1010.7;monocytes: 1337.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011582, HPA044758" Approved Supported Cytosol NA NA 3100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "CAB011582: AB_2112120, HPA044758: AB_2679076" "unprognostic (1.50e-2)" "unprognostic (4.34e-3)" "unprognostic (1.25e-1)" "prognostic favorable (7.78e-4)" "unprognostic (1.26e-1)" "unprognostic (1.83e-1)" "unprognostic (6.73e-3)" "unprognostic (5.03e-2)" "unprognostic (3.40e-2)" "unprognostic (2.48e-1)" "unprognostic (5.46e-2)" "unprognostic (1.53e-1)" "unprognostic (7.64e-3)" "unprognostic (9.14e-3)" "unprognostic (3.16e-2)" "unprognostic (5.72e-3)" "unprognostic (7.64e-3)" 321.4 200.0 178.3 151.9 186.6 246.7 151.5 190.2 298.9 90.9 247.3 86.9 122.2 82.2 17.8 134.3 86.5 91.1 95.5 173.1 198.9 152.9 281.6 168.3 174.3 234.0 213.0 61.9 74.4 35.2 85.7 121.2 208.3 107.0 42.7 8.3 113.1 53.9 157.1 70.4 113.6 70.4 218.0 195.9 92.9 31.5 217.6 75.3 82.1 61.7 86.6 116.8 94.9 256.3 322.8 189.2 72.6 95.4 113.5 205.9 225.9 217.7 114.7 151.5 80.1 157.8 229.7 0.6 301.6 139.8 181.7 93.2 98.8 660.3 31.6 200.2 271.6 224.8 190.2 397.4 575.6 161.0 594.4 455.9 267.6 292.4 221.5 190.0 341.5 78.6 0.5 179.3 125.9 0.8 51.2 407.0 441.3 147.4 510.5 190.8 93.8 120.3 258.2 385.6 87.7 178.5 249.5 1.5 287.3 75.7 1.5 559.5 546.5 209.7 236.0 385.8 453.6 1.1 127.9 116.3 390.5 436.3 507.8 1010.7 1337.0 707.6 69.8 483.7 100.9 314.2 127.7 83.7 1093.1 276.8 118.4 116.2 136.4 107.4 275.8 1534.3 233.3 1401.2 178.3 186.6 190.2 298.9 173.1 198.9 234.0 213.0 208.3 218.0 217.6 256.3 0.0 109.0 323.5 6.2 148.1 249.7 432.8 985.0 92.2 32.1 0.0 0.0 0.0 220.2 616.7 0.0 10.4 499.9 491.5 229.5 0.0 0.0 300.7 0.0 0.0 227.8 251.3 364.1 12.8 0.0 830.3 131.0 73.4 0.0 480.6 0.0 585.7 888.1 3273.8 1.7 17.9 285.0 386.6 3971.6 965.7 1102.9 134.5 1305.5 273.9 41.2 828.6 63.4 138.0 8.0 7.6 0.0 179.0 67.0 82.4 481.0 349.9 0.0 490.0 14.6 210.4 150.6 151.8 12.7 169.4 112.1 154.1 278.8 112.2 0.0 367.3 517.0 GRIP2 KIAA1719 ENSG00000144596 "Glutamate receptor interacting protein 2" Q9C0E4 3 14489107-14556075 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 13.3;skeletal muscle: 35.8;tongue: 12.5" "Cell type enriched" "Detected in many" 4 "Inhibitory neurons: 89.0" "Cancer enhanced" "Detected in single" "testis cancer: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 3.1;BJ hTERT+ SV40 Large T+ RasG12V: 1.9;NTERA-2: 2.1;PC-3: 6.1;SCLC-21H: 3.4;U-2 OS: 2.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035673 Approved Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA035673: AB_10669776" "unprognostic (1.48e-1)" "unprognostic (6.26e-3)" "unprognostic (2.43e-2)" "unprognostic (3.13e-2)" "unprognostic (5.51e-2)" "unprognostic (1.14e-3)" "unprognostic (1.87e-1)" "unprognostic (8.19e-2)" "unprognostic (9.14e-2)" "unprognostic (2.38e-2)" "unprognostic (1.46e-1)" "unprognostic (1.54e-1)" "unprognostic (2.44e-1)" "unprognostic (1.40e-1)" "unprognostic (1.90e-1)" "unprognostic (5.82e-1)" "unprognostic (4.01e-1)" 1.1 1.1 3.0 0.7 2.7 0.0 1.0 0.0 6.2 1.1 0.0 0.8 0.4 1.1 0.4 2.2 0.8 1.2 13.3 0.2 3.5 2.3 0.3 0.4 0.4 2.9 5.8 3.4 0.5 0.3 1.0 3.9 2.1 0.9 1.0 0.3 0.9 0.4 35.8 2.0 1.0 1.0 1.7 1.6 4.5 0.7 9.6 0.3 0.8 12.5 0.7 1.0 1.2 1.8 0.1 0.9 0.0 0.0 0.3 0.2 0.0 0.3 3.1 0.3 1.9 1.2 0.0 0.0 0.7 0.2 0.5 0.2 0.7 0.0 0.0 0.0 0.2 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.1 1.5 6.1 0.0 0.0 0.0 0.0 0.0 3.4 0.6 0.3 0.0 1.0 1.1 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 2.7 0.0 6.2 0.2 3.5 2.9 5.8 2.1 1.7 9.6 1.8 2.3 0.0 0.5 2.3 0.1 0.0 0.1 0.0 1.2 14.9 0.1 1.3 8.5 0.0 0.6 0.0 14.6 0.0 0.7 0.1 0.0 0.0 3.0 2.1 1.4 0.8 4.2 0.0 3.0 0.2 0.0 2.0 2.0 4.9 0.0 0.0 1.1 0.0 0.1 0.0 89.0 0.1 0.0 0.0 0.0 5.2 4.1 0.7 0.0 2.8 0.0 0.5 0.0 0.5 0.9 0.0 0.0 2.2 0.3 0.1 0.0 0.2 0.0 21.9 19.7 4.3 14.7 0.1 0.8 0.2 0.0 0.1 0.3 1.1 0.0 0.0 GRK2 "ADRBK1, BARK1" ENSG00000173020 "G protein-coupled receptor kinase 2" P25098 11 67266473-67286556 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 197.1" "Cell type enhanced" "Detected in many" "Adipocytes: 33.4;dendritic cells: 80.2;Hofbauer cells: 35.8;Macrophages: 37.6;Pancreatic endocrine cells: 32.4;T-cells: 31.0;Theca cells: 36.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 318.0;REH: 417.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005021, CAB037248, HPA060707" Enhanced Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 14: REH - Unknown function" "Cluster 7: Non-specific - Mitochondria" Cytosol "CAB005021: AB_562360, CAB037248: AB_1078280, HPA060707: " "unprognostic (5.58e-2)" "unprognostic (1.75e-1)" "unprognostic (2.01e-2)" "unprognostic (5.33e-2)" "unprognostic (1.38e-1)" "unprognostic (1.29e-3)" "unprognostic (3.31e-2)" "unprognostic (6.17e-2)" "unprognostic (1.11e-1)" "unprognostic (6.35e-2)" "unprognostic (2.22e-1)" "unprognostic (2.55e-2)" "prognostic unfavorable (1.25e-4)" "unprognostic (3.66e-1)" "unprognostic (2.40e-1)" "unprognostic (4.04e-2)" "unprognostic (5.19e-3)" 41.2 35.6 42.4 73.0 42.7 197.1 38.0 31.6 63.8 41.3 16.9 54.3 38.2 34.7 10.4 68.1 41.6 28.8 49.1 44.4 32.5 38.6 47.4 64.1 102.4 36.4 31.6 30.1 33.1 16.2 37.5 25.5 36.5 59.1 33.3 7.9 47.1 22.8 55.6 68.3 88.7 25.1 29.1 186.8 45.4 24.1 36.9 74.7 32.2 40.9 77.8 41.3 47.4 41.8 43.1 29.8 28.1 48.0 22.2 19.9 28.7 24.7 23.4 33.0 27.4 67.1 69.0 215.3 39.5 23.0 44.0 56.7 41.3 33.5 17.2 264.4 26.3 122.5 35.4 30.8 27.9 259.5 238.3 18.0 38.2 26.5 34.8 24.4 42.8 87.7 45.3 107.7 29.0 80.7 147.5 318.0 35.3 125.8 44.4 417.0 55.3 65.2 34.0 54.6 57.0 30.8 36.9 52.9 90.5 16.9 49.7 283.0 24.5 26.7 34.8 33.6 28.4 69.2 67.5 195.3 34.0 153.6 24.6 12.6 17.8 19.2 8.4 27.6 6.3 6.1 6.3 7.0 10.2 6.4 5.0 4.9 35.7 6.9 33.7 9.0 4.4 15.9 42.4 42.7 31.6 63.8 44.4 32.5 36.4 31.6 36.5 29.1 36.9 41.8 33.4 3.2 17.9 0.0 16.7 0.0 0.0 0.0 0.0 0.0 24.5 19.7 0.0 0.0 4.3 5.5 0.0 8.9 80.2 0.0 1.9 10.3 0.0 16.6 14.7 9.0 0.0 0.0 0.0 12.6 5.9 6.1 0.0 18.9 21.5 22.3 0.0 0.0 35.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.6 0.0 0.0 8.8 0.0 0.0 0.0 0.0 32.4 0.0 0.0 17.7 0.0 0.0 5.6 0.7 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 9.6 31.0 36.3 0.0 0.0 GRM7 "GLUR7, GPRC1G, mGlu7, MGLUR7, PPP1R87" ENSG00000196277 "Glutamate metabotropic receptor 7" Q14831 3 6770001-7741533 "G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Cardiomyopathy, Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1;parathyroid gland: 4.4" "Group enriched" "Detected in some" 14 "Excitatory neurons: 773.1;Inhibitory neurons: 597.7;Oligodendrocyte precursor cells: 1189.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 9 "SH-SY5Y: 4.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015964 Uncertain Cytosol NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA015964: " "unprognostic (2.04e-2)" "unprognostic (7.03e-3)" "unprognostic (1.43e-1)" "unprognostic (9.37e-2)" "unprognostic (8.48e-3)" "unprognostic (2.58e-1)" "unprognostic (7.30e-2)" "unprognostic (3.50e-2)" "unprognostic (2.20e-1)" "unprognostic (1.78e-1)" "unprognostic (1.46e-2)" "unprognostic (2.54e-1)" "unprognostic (6.84e-6)" "unprognostic (1.45e-1)" "unprognostic (2.82e-2)" "unprognostic (5.43e-2)" "unprognostic (2.59e-2)" 0.2 2.0 2.8 0.0 2.9 0.0 0.1 0.1 3.8 0.9 0.0 0.1 0.2 0.9 0.0 0.0 0.2 0.0 0.0 3.9 5.1 0.0 0.1 0.1 0.0 2.0 3.0 0.1 0.0 4.4 0.0 0.1 1.7 0.3 0.1 1.1 0.7 0.3 0.0 0.0 0.0 2.3 3.7 0.1 0.0 1.1 5.0 0.3 0.1 0.0 0.0 0.2 0.1 1.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 2.9 0.1 3.8 3.9 5.1 2.0 3.0 1.7 3.7 5.0 1.7 0.1 0.0 0.0 29.4 0.0 0.1 1.2 0.1 0.0 24.1 0.1 0.5 1.1 4.3 0.7 0.0 8.4 0.0 0.1 0.0 1.9 0.0 32.7 0.1 2.7 0.2 0.0 0.0 773.1 0.0 0.1 1.6 0.0 0.1 1.3 0.1 0.0 0.0 0.1 1.7 597.7 0.0 0.0 0.0 1.2 41.7 0.3 0.4 0.0 13.1 0.1 1.3 0.0 1189.3 56.9 0.0 0.0 0.0 0.0 0.7 0.0 0.1 8.0 3.5 6.6 0.7 0.4 2.7 0.8 0.0 0.0 0.0 0.1 0.5 0.0 0.7 GSDME "DFNA5, ICERE-1" ENSG00000105928 "Gasdermin E" O60443 7 24698355-24757940 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Necrosis "Deafness, Non-syndromic deafness, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 168.1;Distal tubular cells: 41.1;Extravillous trophoblasts: 26.5;Hofbauer cells: 39.9;Syncytiotrophoblasts: 104.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 9.0;myeloid DC: 5.9;naive B-cell: 8.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011326, CAB019306" Approved Supported Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "CAB019306: , HPA011326: AB_1847629" "unprognostic (1.08e-1)" "unprognostic (1.77e-2)" "unprognostic (6.29e-2)" "unprognostic (6.36e-3)" "unprognostic (6.70e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (2.49e-5)" "unprognostic (4.35e-2)" "unprognostic (1.34e-1)" "unprognostic (1.35e-1)" "unprognostic (2.23e-1)" "unprognostic (1.24e-1)" "unprognostic (1.13e-3)" "unprognostic (1.48e-3)" "unprognostic (6.70e-2)" "unprognostic (1.06e-1)" "unprognostic (5.90e-2)" 13.5 7.8 16.4 2.9 16.7 0.5 7.6 13.3 18.0 17.3 9.2 6.4 7.7 24.8 15.3 3.6 14.3 8.5 9.7 18.1 15.0 13.3 4.5 4.4 5.8 19.4 18.7 16.9 2.6 7.3 7.0 35.0 16.1 7.5 2.4 6.3 3.1 21.1 7.8 3.0 26.8 15.1 16.5 1.8 3.9 12.9 14.1 5.8 14.5 5.2 3.8 15.0 10.1 26.6 31.4 21.7 9.6 41.2 51.4 28.6 16.4 24.1 63.6 24.5 34.3 22.9 1.1 0.5 20.6 66.4 81.7 20.5 5.8 105.4 42.8 0.1 2.1 0.8 39.3 48.0 43.0 0.1 1.5 31.3 75.3 43.5 103.1 73.0 42.3 13.8 3.0 5.2 55.3 0.4 1.9 0.8 10.2 0.1 15.7 0.2 33.6 0.0 74.5 21.9 0.4 60.0 36.5 0.6 42.3 24.3 2.2 2.8 27.9 23.1 39.7 31.6 29.2 2.4 0.6 15.5 69.8 0.1 5.8 0.0 1.9 0.0 0.0 0.2 0.0 9.0 0.1 0.0 5.9 8.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.6 16.4 16.7 13.3 18.0 18.1 15.0 19.4 18.7 16.1 16.5 14.1 26.6 1.0 6.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.1 3.9 0.0 0.0 0.6 5.5 0.0 168.1 0.0 0.0 41.1 1.9 0.0 0.7 16.9 1.3 0.0 0.0 0.0 0.9 26.5 4.3 0.0 1.0 0.0 4.8 0.0 0.0 39.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 8.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 8.8 1.5 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 104.7 0.7 0.9 0.0 0.0 GSK3A ENSG00000105723 "Glycogen synthase kinase 3 alpha" P49840 19 42226225-42242625 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism, Neurogenesis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Signal transduction inhibitor, Transferase" "Alzheimer disease, Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004422, HPA028423" Approved Approved Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Cytosol "CAB004422: AB_627680, HPA028423: AB_10612116" "unprognostic (5.46e-2)" "unprognostic (1.50e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (4.02e-4)" "unprognostic (1.35e-1)" "unprognostic (3.96e-2)" "prognostic unfavorable (1.13e-4)" "unprognostic (3.80e-3)" "unprognostic (2.27e-1)" "unprognostic (2.87e-1)" "unprognostic (4.99e-2)" "unprognostic (3.36e-1)" "unprognostic (2.69e-1)" "unprognostic (2.77e-2)" "unprognostic (4.49e-2)" "unprognostic (7.22e-2)" "unprognostic (8.22e-3)" 30.6 43.3 37.5 22.1 44.0 30.7 29.4 33.6 90.2 34.5 13.7 39.4 40.9 38.1 21.7 40.2 31.8 18.7 45.8 47.0 30.9 39.2 30.4 30.4 23.7 39.1 30.9 34.5 29.6 34.4 32.1 19.9 37.6 33.3 21.1 32.6 31.7 25.9 79.2 42.9 37.1 23.0 20.5 31.2 35.4 30.6 38.2 32.9 29.6 42.0 22.7 37.7 33.0 49.5 57.0 102.1 54.3 53.2 30.3 29.5 25.9 42.7 36.1 49.6 46.0 39.0 39.6 41.0 39.6 33.9 44.8 25.6 49.5 51.3 38.5 33.8 74.5 41.5 41.3 42.7 42.7 51.7 54.0 27.2 45.8 41.9 47.7 44.8 46.5 34.7 73.9 63.0 41.1 80.0 87.7 39.0 42.8 84.5 40.0 58.4 33.8 30.4 43.4 76.1 63.7 67.5 52.8 71.6 36.6 42.8 39.5 69.5 40.6 52.0 40.9 31.0 71.9 65.8 82.8 38.7 66.4 49.8 58.2 0.9 0.5 1.4 0.5 0.8 0.9 0.3 0.3 0.7 0.2 0.2 0.2 0.8 1.7 0.3 0.4 0.6 0.5 0.7 37.5 44.0 33.6 90.2 47.0 30.9 39.1 30.9 37.6 20.5 38.2 49.5 45.6 6.4 16.2 5.2 16.4 24.6 17.7 7.3 14.8 40.8 35.0 39.2 12.9 17.2 7.9 16.5 62.6 23.4 31.4 42.3 3.9 15.2 8.6 19.6 21.5 26.6 23.4 28.6 15.1 17.2 25.3 21.3 16.8 25.0 2.5 27.2 18.2 13.9 20.3 60.6 14.9 29.7 6.1 21.3 15.4 14.6 17.7 25.2 16.0 8.4 14.4 41.8 21.6 11.1 12.2 24.2 24.3 16.6 12.6 29.0 45.0 16.0 5.9 47.0 6.6 50.4 27.4 16.4 19.4 20.2 28.1 44.1 20.6 42.6 28.8 30.1 GSPT2 "eRF3b, FLJ10441" ENSG00000189369 "G1 to S phase transition 2" Q8IYD1 X 51743442-51746232 "Predicted intracellular proteins" "Cell cycle, Nonsense-mediated mRNA decay, Protein biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 95.5;Late spermatids: 189.0;Muller glia cells: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NTERA-2: 47.6;PC-3: 53.8;SuSa: 38.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044769, HPA074588" Approved Enhanced Cytosol NA NA 130000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 21: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA044769: AB_10963577, HPA074588: " "unprognostic (8.55e-3)" "unprognostic (1.76e-1)" "unprognostic (2.81e-1)" "unprognostic (2.71e-3)" "unprognostic (3.39e-1)" "unprognostic (4.12e-2)" "unprognostic (1.54e-2)" "unprognostic (3.43e-1)" "unprognostic (1.39e-1)" "unprognostic (1.83e-1)" "unprognostic (1.21e-1)" "unprognostic (3.01e-1)" "unprognostic (1.72e-1)" "unprognostic (2.08e-2)" "unprognostic (1.54e-2)" "unprognostic (9.76e-3)" "unprognostic (1.07e-1)" 6.2 6.5 6.8 5.8 7.1 2.8 6.2 5.6 7.5 4.4 5.3 5.0 3.2 5.4 7.5 2.7 5.6 5.1 6.8 6.9 10.7 6.3 11.2 5.5 9.2 5.1 7.1 9.9 4.8 6.1 6.5 2.4 6.1 6.8 3.5 7.7 6.3 6.1 5.9 2.7 5.0 5.3 5.3 5.8 3.9 13.3 9.5 10.4 6.0 5.3 8.6 4.8 2.3 4.7 0.0 9.9 19.7 0.0 13.6 11.8 0.0 11.3 1.9 8.0 10.0 6.3 10.0 29.3 0.0 9.7 24.6 3.2 0.0 5.3 9.1 0.0 12.7 0.4 0.0 0.0 10.1 0.0 12.3 15.7 2.5 7.0 7.1 13.6 11.7 13.4 7.9 2.2 14.2 0.0 2.6 1.8 47.6 0.0 53.8 14.0 18.6 0.0 14.5 10.6 0.0 16.6 0.0 0.0 10.5 38.9 0.0 9.5 7.5 7.9 16.0 7.4 7.5 0.0 17.3 0.0 10.5 1.9 8.9 2.9 2.5 1.6 4.5 3.6 4.5 7.9 3.9 4.3 8.2 8.1 6.3 5.5 0.3 6.5 2.7 6.9 5.6 3.6 6.8 7.1 5.6 7.5 6.9 10.7 5.1 7.1 6.1 5.3 9.5 4.7 6.4 12.8 11.8 3.6 10.1 1.8 5.3 8.9 3.4 17.0 4.2 7.0 17.9 14.3 8.0 14.7 8.4 9.6 11.5 2.0 5.9 14.2 95.5 1.4 10.7 8.3 3.0 4.2 3.9 8.7 4.3 11.2 3.1 1.3 10.8 6.3 6.1 20.3 6.2 11.8 4.3 3.5 2.0 7.6 2.1 189.0 12.8 4.9 3.6 1.9 9.8 61.4 14.4 3.5 2.6 5.6 5.5 18.8 7.6 6.5 0.8 11.5 10.0 10.4 26.3 8.2 7.6 11.6 10.4 2.5 1.4 3.4 7.5 15.7 3.2 3.9 GSR ENSG00000104687 "Glutathione-disulfide reductase" P00390 8 30678066-30727846 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 32.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001538, CAB008632, HPA064806" Approved Supported Cytosol NA NA 81000000 "Cluster 46: Basophils - DNA binding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" Cytosol "CAB008632: AB_1616690, HPA001538: AB_1078986, HPA064806: " "unprognostic (1.23e-1)" "prognostic favorable (3.37e-4)" "prognostic favorable (4.08e-5)" "unprognostic (2.89e-3)" "unprognostic (1.62e-1)" "unprognostic (3.50e-1)" "prognostic unfavorable (3.26e-5)" "unprognostic (3.61e-2)" "unprognostic (1.01e-1)" "unprognostic (4.15e-2)" "unprognostic (2.83e-2)" "unprognostic (6.92e-3)" "prognostic favorable (1.80e-4)" "unprognostic (2.31e-3)" "unprognostic (2.26e-1)" "unprognostic (1.01e-1)" "unprognostic (1.29e-1)" 13.6 23.3 12.3 18.7 11.1 25.9 11.0 10.6 11.7 28.5 25.8 42.5 54.3 16.0 21.6 37.3 21.6 30.5 25.4 12.9 12.5 45.3 35.8 17.4 23.6 9.5 14.2 23.1 26.5 82.3 14.8 23.5 12.0 35.3 46.6 12.8 25.8 29.4 28.9 12.8 50.8 17.9 10.7 22.1 41.8 11.6 17.6 26.7 16.9 21.3 24.0 22.5 27.7 11.2 49.4 197.8 35.9 40.1 35.8 38.3 29.1 23.4 46.8 31.8 36.7 66.0 31.3 95.8 94.8 32.0 96.1 59.2 62.3 51.1 33.1 22.6 40.7 104.6 67.0 197.8 88.4 38.6 159.7 72.6 28.5 48.9 20.9 33.5 43.3 57.3 73.2 55.1 67.9 44.1 147.1 32.0 65.4 191.9 31.5 43.8 41.9 59.3 56.0 124.3 28.2 31.8 31.2 87.8 58.8 40.7 37.5 32.6 63.8 21.0 34.7 37.3 35.2 20.2 29.4 70.0 51.9 51.8 62.4 32.3 5.9 15.0 5.0 5.4 8.8 3.6 4.5 5.4 6.0 2.3 2.8 3.7 8.2 3.6 7.9 3.9 4.5 3.1 12.3 11.1 10.6 11.7 12.9 12.5 9.5 14.2 12.0 10.7 17.6 11.2 8.2 3.2 20.8 12.7 13.7 4.2 15.2 9.4 52.3 6.7 6.7 5.0 26.8 30.0 15.0 12.9 16.7 17.0 20.3 61.8 9.8 11.4 8.4 61.4 13.4 9.9 34.1 28.6 18.1 19.8 6.3 10.0 33.1 41.3 6.3 64.3 12.1 43.4 18.2 3.3 27.4 51.7 8.2 40.5 5.8 18.9 7.2 22.1 8.8 11.2 20.6 12.6 17.5 12.5 10.0 15.2 32.0 10.9 15.6 27.5 75.7 19.0 11.7 8.0 6.6 7.0 8.6 1.2 3.4 39.6 5.4 6.4 17.3 17.2 47.5 33.5 GSTA1 ENSG00000243955 "Glutathione S-transferase alpha 1" P08263 6 52791371-52803860 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Oxidoreductase, Peroxidase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 916.5;kidney: 943.1;liver: 2610.5" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 1652.6;Granulosa cells: 3177.1;Proximal enterocytes: 4294.8;Proximal tubular cells: 3190.6;Theca cells: 4578.2" "Cancer enriched" "Detected in many" 4 "liver cancer: 555.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 14 "Hep G2: 263.9" "HPA004342, HPA048934, HPA053817" Supported Supported Cytosol NA NA 27800000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA004342: AB_1078987, HPA048934: AB_2680563, HPA053817: AB_2630367" "unprognostic (4.84e-3)" "unprognostic (2.40e-2)" "unprognostic (3.40e-1)" "unprognostic (4.78e-2)" "unprognostic (1.72e-1)" "unprognostic (1.26e-1)" "unprognostic (1.00e-2)" "prognostic favorable (8.66e-4)" "unprognostic (5.75e-2)" "unprognostic (6.90e-3)" "unprognostic (3.00e-1)" "unprognostic (8.27e-2)" "prognostic unfavorable (3.71e-4)" "unprognostic (1.21e-1)" "unprognostic (4.26e-3)" "unprognostic (1.02e-1)" "unprognostic (2.16e-2)" 0.5 916.5 0.0 2.5 0.0 0.0 4.2 0.0 0.2 2.0 0.0 7.3 672.0 0.4 7.0 5.3 86.1 119.5 0.2 0.0 0.0 943.1 2610.5 12.2 0.5 0.0 0.0 78.9 148.6 0.0 0.2 0.5 0.0 18.7 8.1 0.0 21.5 0.6 0.1 1.2 674.6 0.3 0.0 0.2 135.5 336.8 0.3 0.1 0.1 0.0 11.5 2.2 5.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 19.4 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.5 0.1 263.9 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.4 2.1 0.0 0.2 1.5 2.1 0.3 0.0 0.0 1.1 0.0 0.2 0.5 0.5 0.1 0.6 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 6.4 7.7 0.0 13.5 0.0 5.0 35.7 0.0 0.0 7.0 1.5 0.0 453.2 159.9 73.5 0.0 0.1 0.1 5.8 536.1 71.3 11.8 0.4 0.1 3.1 3.0 45.5 0.0 1652.6 0.2 7.3 116.7 0.5 2.5 3177.1 26.4 1013.9 0.1 0.0 0.0 165.6 42.7 31.5 0.0 43.0 65.6 25.3 0.0 0.0 13.3 0.0 1.0 0.0 0.1 629.1 187.4 4.5 0.2 27.6 4294.8 3190.6 533.5 0.0 0.0 0.0 98.6 36.8 3.4 6.8 0.0 0.5 10.4 4578.2 295.3 58.7 GSTA2 GST2 ENSG00000244067 "Glutathione S-transferase alpha 2" P09210 6 52750087-52763475 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 696.0;liver: 2058.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 201.6;Distal tubular cells: 213.2;Exocrine glandular cells: 239.6;Pancreatic endocrine cells: 334.7;Proximal enterocytes: 367.0;Proximal tubular cells: 1186.6;Respiratory ciliated cells: 435.5" "Group enriched" "Detected in many" 16 "liver cancer: 124.6;renal cancer: 48.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "CACO-2: 25.9;Hep G2: 20.0" "HPA004342, HPA048934, HPA053817" Supported Supported Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA004342: AB_1078987, HPA048934: AB_2680563, HPA053817: AB_2630367" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (2.72e-2)" "unprognostic (1.15e-1)" "unprognostic (6.43e-3)" "unprognostic (2.41e-1)" "unprognostic (1.30e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (4.34e-2)" "unprognostic (1.91e-1)" "unprognostic (6.54e-2)" 0.4 4.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.6 149.5 0.0 0.7 0.1 2.5 109.4 0.0 0.0 0.0 696.0 2058.5 4.8 0.1 0.0 0.0 0.2 299.2 0.0 0.0 0.1 0.0 3.8 0.1 0.0 0.5 0.0 0.0 0.0 115.5 0.0 0.0 0.0 11.7 44.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 25.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.2 0.0 20.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 1.7 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.6 0.0 0.0 0.3 0.6 0.5 0.5 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 1.7 0.0 0.2 1.5 0.0 0.0 0.1 0.1 0.0 201.6 31.1 16.5 0.0 0.0 0.0 0.1 213.2 8.1 6.9 0.0 0.0 0.6 0.0 0.0 0.0 239.6 0.2 0.5 7.7 0.0 0.0 37.2 0.7 124.2 0.1 0.0 0.0 13.7 2.0 2.2 0.0 14.6 1.2 5.1 0.0 0.0 5.2 0.0 0.0 0.0 0.1 334.7 18.8 0.4 0.0 3.9 367.0 1186.6 435.5 0.0 0.0 0.0 1.5 1.9 0.7 0.0 0.0 0.0 2.6 10.4 30.1 1.3 GSTA3 ENSG00000174156 "Glutathione S-transferase alpha 3" Q16772 6 52896639-52909698 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 67.3;fallopian tube: 65.4;placenta: 22.7;skin 1: 26.0" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 194.9;Syncytiotrophoblasts: 515.3;Theca cells: 91.3" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.5;testis cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SuSa: 1.4" "HPA004342, HPA048934, HPA053817" Approved Supported Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA004342: AB_1078987, HPA048934: AB_2680563, HPA053817: AB_2630367" "unprognostic (7.51e-2)" "unprognostic (7.06e-3)" "unprognostic (3.10e-1)" "unprognostic (5.53e-2)" "unprognostic (4.38e-3)" "unprognostic (2.86e-3)" "unprognostic (1.81e-1)" "unprognostic (1.41e-1)" "unprognostic (1.93e-1)" "unprognostic (9.35e-2)" 0.0 67.3 0.0 0.1 0.1 0.0 1.8 0.0 0.0 1.1 0.5 0.0 0.3 0.8 0.8 0.0 65.4 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.1 0.5 0.9 0.1 2.9 0.0 22.7 0.0 0.1 0.0 0.0 0.3 0.2 0.0 26.0 0.4 0.1 0.0 0.0 2.4 11.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.5 0.0 0.0 0.3 0.1 0.0 0.0 1.1 0.0 0.0 1.0 0.0 0.9 0.0 0.0 0.4 0.0 0.0 0.0 6.2 0.0 0.0 194.9 0.0 0.0 0.0 0.0 1.3 47.0 0.5 0.5 0.0 0.0 0.0 0.0 7.5 1.1 0.0 0.7 1.3 7.4 0.0 0.4 15.7 0.0 0.0 0.0 2.0 0.0 0.4 2.1 1.5 0.0 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 24.8 0.0 0.0 0.0 0.8 0.5 0.5 0.0 9.8 515.3 0.1 91.3 0.0 0.0 GSTA5 ENSG00000182793 "Glutathione S-transferase alpha 5" Q7RTV2 6 52831655-52840843 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 10 "Smooth muscle cells: 23.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA004342, HPA048934, HPA053817" Uncertain Approved Cytosol NA NA "Cluster 10: Non-specific - Unknown function" Cytosol "HPA004342: AB_1078987, HPA048934: AB_2680563, HPA053817: AB_2630367" "unprognostic (1.97e-2)" "unprognostic (2.83e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 2.2 0.4 0.0 0.0 0.0 23.6 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 GSTM3 GST5 ENSG00000134202 "Glutathione S-transferase mu 3" P21266 1 109733932-109741038 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 377.9" "Cell type enhanced" "Detected in all" "Distal tubular cells: 802.2;Early spermatids: 2092.4;Late spermatids: 3843.4;Spermatocytes: 1177.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 3.4;gdT-cell: 3.1;memory CD4 T-cell: 3.9;memory CD8 T-cell: 2.2;naive CD4 T-cell: 7.8;naive CD8 T-cell: 4.3;T-reg: 1.9" "Group enriched" "Detected in many" 7 "granulocytes: 3.4;T-cells: 7.8" "Cell line enhanced" "Detected in many" "SK-BR-3: 228.4;T-47d: 479.6;WM-115: 186.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB017130, HPA035190, CAB040583, HPA055972" Enhanced Approved Cytosol NA NA 790000 "Cluster 32: T-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB017130: , CAB040583: , HPA035190: AB_10795023, HPA055972: AB_2682992" "unprognostic (2.13e-2)" "unprognostic (2.76e-2)" "unprognostic (1.95e-1)" "unprognostic (5.87e-2)" "unprognostic (1.25e-1)" "unprognostic (7.28e-2)" "unprognostic (3.28e-3)" "unprognostic (1.98e-1)" "prognostic unfavorable (1.89e-4)" "unprognostic (3.45e-1)" "unprognostic (1.51e-1)" "unprognostic (2.30e-1)" "unprognostic (6.16e-3)" "unprognostic (1.38e-2)" "unprognostic (1.21e-2)" "unprognostic (1.90e-2)" "unprognostic (3.48e-2)" 38.7 39.0 56.9 11.0 61.1 3.3 83.5 50.3 69.1 52.7 109.7 45.0 46.8 32.1 243.2 53.6 35.1 47.0 74.8 56.9 63.6 188.1 20.0 23.6 6.2 54.4 54.8 120.4 101.0 41.1 33.7 21.6 55.5 47.5 19.9 21.1 22.6 165.9 65.8 57.2 27.8 58.3 57.5 14.1 76.2 377.9 61.6 13.2 57.9 51.2 7.9 57.1 53.2 58.3 0.2 6.9 49.3 0.1 64.5 39.9 8.5 54.3 9.4 58.2 56.2 21.8 1.9 0.1 30.8 27.8 40.1 2.6 10.0 22.3 80.5 0.3 14.9 50.8 152.1 33.9 69.5 0.0 115.2 40.3 27.0 87.8 0.1 63.5 73.1 61.9 4.7 0.6 26.6 30.0 14.5 1.2 5.3 0.2 93.1 0.4 31.9 2.3 16.3 117.1 86.1 46.0 112.5 228.4 10.5 14.1 479.6 75.3 57.9 0.8 20.9 59.6 36.3 7.7 13.1 0.2 0.6 0.1 186.9 0.3 0.1 3.4 3.1 0.1 0.8 0.3 3.9 2.2 0.1 0.2 7.8 4.3 0.9 0.7 0.1 0.5 1.9 1.5 56.9 61.1 50.3 69.1 56.9 63.6 54.4 54.8 55.5 57.5 61.6 58.3 22.2 6.4 11.5 18.3 7.0 143.5 97.2 104.4 50.1 17.5 196.1 176.8 88.0 50.1 35.9 222.5 6.2 16.3 8.7 17.3 802.2 88.0 2092.4 51.4 40.6 32.9 50.4 33.0 7.5 149.5 9.0 131.6 43.8 93.6 9.5 22.7 58.2 14.2 10.6 15.2 8.0 24.9 28.5 13.9 54.1 3843.4 385.5 15.1 60.5 2.8 3.5 247.5 2.1 14.6 1.7 126.4 32.5 276.1 3.4 53.7 116.9 38.9 5.4 19.2 190.7 23.8 94.4 1177.6 54.4 71.9 107.4 10.3 24.4 121.4 44.1 80.8 GTDC1 "FLJ11753, Hmat-Xa" ENSG00000121964 "Glycosyltransferase like domain containing 1" Q4AE62 2 143938068-144332568 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 330.7;Inhibitory neurons: 188.0;Microglial cells: 130.2;Oligodendrocyte precursor cells: 196.6;Oligodendrocytes: 399.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036694 Approved Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 36: HEL - Hemostasis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA036694: AB_10671709" "unprognostic (1.44e-1)" "unprognostic (1.22e-1)" "unprognostic (9.00e-3)" "unprognostic (3.36e-2)" "unprognostic (5.79e-2)" "unprognostic (1.28e-1)" "unprognostic (1.81e-7)" "unprognostic (8.01e-2)" "unprognostic (4.13e-2)" "unprognostic (2.51e-1)" "unprognostic (6.22e-3)" "unprognostic (6.96e-2)" "prognostic unfavorable (6.60e-4)" "unprognostic (2.44e-1)" "unprognostic (8.23e-2)" "unprognostic (6.31e-3)" "unprognostic (1.89e-1)" 15.2 12.6 15.9 7.5 18.0 14.2 9.4 11.7 21.1 11.8 4.2 7.1 4.2 6.7 9.4 7.4 5.8 10.1 15.7 17.3 14.3 9.6 6.7 7.8 11.0 15.4 14.7 12.0 7.2 7.4 4.2 9.5 15.4 6.1 6.7 7.7 6.1 5.8 10.0 5.1 4.8 5.9 17.2 13.5 5.2 12.2 14.3 8.7 10.5 11.3 11.6 9.5 5.5 24.1 6.9 2.8 20.0 3.7 20.1 18.4 6.0 4.7 11.9 10.3 14.2 3.1 6.3 14.8 3.3 8.5 6.6 1.9 4.0 7.1 21.9 19.2 4.7 23.0 2.6 3.3 8.3 9.4 12.0 12.8 17.1 11.1 16.2 7.0 14.9 6.1 4.2 16.8 23.7 3.2 2.5 10.3 5.7 5.3 4.5 7.0 10.4 4.0 11.4 14.0 10.2 7.9 9.1 7.7 9.3 12.4 5.1 10.5 9.2 11.4 8.3 5.1 6.0 10.6 0.0 8.5 6.6 6.2 15.6 2.3 2.6 7.9 5.5 2.4 11.8 4.3 3.6 9.3 2.1 3.5 0.8 5.9 11.3 8.5 2.7 0.7 5.1 3.6 15.9 18.0 11.7 21.1 17.3 14.3 15.4 14.7 15.4 17.2 14.3 24.1 7.7 9.6 23.2 82.3 11.2 7.1 4.4 6.4 4.0 20.4 5.2 5.0 18.5 4.3 14.9 5.5 4.2 4.1 13.6 6.1 5.9 4.5 9.9 3.3 11.4 9.6 4.2 9.4 330.7 10.5 5.2 16.0 4.6 5.6 17.7 15.5 20.3 3.8 10.2 18.5 188.0 3.2 4.1 18.3 11.8 7.7 12.8 16.4 5.4 130.2 11.6 10.8 18.6 196.6 399.6 9.4 4.0 13.9 8.6 4.2 2.6 7.7 13.4 3.9 13.1 25.2 17.0 5.4 23.5 4.9 4.7 4.2 19.7 14.8 3.7 8.7 GUCY1B1 "GC-S-beta-1, GC-SB3, GUC1B3, GUCY1B3" ENSG00000061918 "Guanylate cyclase 1 soluble subunit beta 1" Q02153 4 155758992-155807811 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "cGMP biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 20.2;Ductal cells: 22.9;Glandular and luminal cells: 15.5;Proximal tubular cells: 22.2;Smooth muscle cells: 36.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "intermediate monocyte: 7.2;non-classical monocyte: 23.9" "Lineage enriched" "Detected in many" 13 "monocytes: 23.9" "Cell line enhanced" "Detected in many" "HEL: 46.0;Karpas-707: 23.7;MOLT-4: 29.9;RPTEC TERT1: 42.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010890, HPA020870" Approved Approved Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "CAB010890: AB_259911, HPA020870: AB_1850444" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (3.55e-2)" "unprognostic (9.10e-3)" "unprognostic (4.69e-2)" "unprognostic (1.41e-2)" "unprognostic (6.88e-2)" "unprognostic (6.69e-3)" "unprognostic (3.03e-3)" "unprognostic (1.47e-1)" "unprognostic (8.37e-2)" "unprognostic (2.84e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (7.35e-3)" "prognostic unfavorable (3.23e-4)" "unprognostic (2.14e-1)" "unprognostic (6.36e-3)" 13.8 7.1 23.6 15.6 30.0 2.2 10.0 5.3 36.6 12.6 0.0 28.9 5.8 16.4 6.0 8.1 13.7 13.3 18.7 30.1 28.2 13.2 7.7 16.5 10.4 9.8 13.9 5.8 10.9 50.3 6.0 43.6 22.8 13.6 8.7 34.7 5.5 12.2 5.9 3.5 11.1 25.0 6.4 11.0 13.8 2.4 14.8 7.2 7.3 14.9 7.3 10.0 11.1 17.0 0.0 0.5 6.5 0.0 2.2 11.4 0.0 2.0 3.6 0.2 0.1 0.0 0.0 0.0 3.0 1.1 5.0 0.1 13.6 0.3 0.8 0.0 4.6 46.0 0.0 0.0 1.2 0.0 0.0 5.1 0.4 0.0 0.2 4.2 0.1 10.2 0.0 23.7 3.0 2.1 29.9 0.1 0.4 0.0 3.2 3.5 0.9 0.7 42.9 4.4 0.7 7.8 0.0 0.2 0.0 6.4 0.0 0.0 0.0 7.3 1.6 12.4 9.5 0.3 0.0 0.0 15.6 0.0 0.0 1.4 0.5 0.5 0.0 7.2 0.0 0.1 0.0 0.0 1.8 0.2 0.0 0.0 0.5 1.3 23.9 1.6 0.0 5.8 23.6 30.0 5.3 36.6 30.1 28.2 9.8 13.9 22.8 6.4 14.8 17.0 20.2 6.4 7.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 2.2 0.0 0.0 0.0 9.2 0.0 1.1 1.1 0.0 5.9 22.9 0.0 3.7 4.3 3.4 0.0 0.0 0.0 4.2 0.2 5.4 0.0 15.5 1.3 4.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.0 22.2 0.0 0.0 0.0 0.0 36.1 0.0 0.0 0.0 0.0 0.7 0.4 0.7 0.0 0.0 H6PD "GDH, H6PDH" ENSG00000049239 "Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase" O95479 1 9234774-9271337 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Hydrolase, Multifunctional enzyme, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 94.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 164.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 68.9;ASC TERT1: 78.9;HSkMC: 77.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004824, HPA005440" Approved Uncertain Cytosol "Intracellular and membrane" NA NA 140000000 "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Cytosol "HPA004824: AB_1079037, HPA005440: AB_1079036" "unprognostic (4.83e-3)" "unprognostic (3.91e-2)" "unprognostic (1.18e-1)" "unprognostic (3.49e-1)" "unprognostic (5.53e-3)" "unprognostic (2.86e-2)" "unprognostic (8.35e-2)" "unprognostic (5.18e-2)" "unprognostic (9.73e-2)" "unprognostic (1.26e-3)" "unprognostic (2.16e-2)" "unprognostic (7.35e-3)" "unprognostic (8.20e-2)" "unprognostic (3.61e-1)" "unprognostic (1.30e-1)" "unprognostic (8.65e-2)" "unprognostic (1.95e-1)" 29.0 30.5 7.5 12.6 11.6 9.7 23.0 8.2 9.0 22.6 18.8 15.1 11.2 25.7 14.4 13.5 28.3 12.6 18.9 6.4 7.8 11.5 94.5 20.3 12.4 14.4 10.8 44.9 18.9 10.6 12.7 14.1 11.4 19.5 9.1 4.2 56.2 13.1 48.3 35.7 16.8 16.6 9.6 14.5 18.7 8.1 11.4 13.1 14.7 21.0 11.4 16.7 16.5 10.9 9.9 8.0 6.8 25.5 68.9 78.9 6.4 9.8 24.0 7.1 10.9 1.5 20.1 10.9 11.2 15.3 9.1 10.3 1.8 4.8 10.3 32.8 2.2 0.0 2.8 6.7 38.6 3.5 4.1 77.7 9.1 17.2 11.1 15.6 32.9 5.9 2.9 18.2 14.0 5.7 3.9 8.2 3.7 7.5 4.6 1.2 0.9 9.3 9.1 4.0 2.3 12.0 12.9 10.0 12.0 4.7 7.5 17.4 32.9 24.3 3.9 6.2 2.8 24.1 7.6 2.5 40.8 15.6 15.7 1.6 2.3 0.3 1.6 2.4 1.3 1.3 1.2 1.5 1.0 1.6 1.2 1.1 1.5 1.2 2.3 1.4 1.1 1.5 7.5 11.6 8.2 9.0 6.4 7.8 14.4 10.8 11.4 9.6 11.4 10.9 24.1 25.6 29.5 17.9 10.1 14.3 13.2 16.9 18.8 19.6 10.3 8.3 17.5 58.6 18.8 20.2 27.1 11.2 9.1 16.6 0.0 22.9 0.8 11.2 36.0 19.8 7.8 9.0 8.4 21.3 8.5 33.6 5.6 15.5 3.8 29.9 19.6 164.0 12.1 16.8 9.1 15.1 8.2 25.4 11.4 2.9 48.1 14.2 12.4 13.1 51.6 10.4 19.6 16.6 18.6 20.0 17.0 36.9 4.5 17.2 23.1 7.4 19.1 10.9 0.0 50.5 11.7 4.6 5.5 10.5 12.8 5.9 11.6 26.1 23.6 14.2 HAL HIS ENSG00000084110 "Histidine ammonia-lyase" P42357 12 95972662-95996365 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Histidine metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "liver: 198.2;skin 1: 61.1" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 129.6" "Cancer enriched" "Detected in some" 11 "liver cancer: 23.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "basophil: 56.9;neutrophil: 73.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 73.3" "Cell line enhanced" "Detected in some" "BEWO: 2.2;NB-4: 2.8;THP-1: 11.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA038547, HPA038548" Enhanced Approved Cytosol NA NA 280000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" Cytosol "HPA038547: AB_10669541, HPA038548: AB_10673175" "unprognostic (3.39e-1)" "unprognostic (4.46e-2)" "unprognostic (1.53e-2)" "unprognostic (1.46e-1)" "unprognostic (2.32e-2)" "unprognostic (1.20e-2)" "unprognostic (5.05e-2)" "unprognostic (2.80e-2)" "unprognostic (1.52e-1)" "unprognostic (1.33e-2)" "unprognostic (9.41e-2)" "unprognostic (2.45e-1)" "unprognostic (1.31e-3)" "unprognostic (1.89e-2)" "unprognostic (3.74e-1)" "unprognostic (4.03e-2)" "unprognostic (2.87e-2)" 1.4 0.3 0.1 2.9 0.1 11.5 2.2 0.1 0.4 0.8 0.1 0.5 0.6 0.4 0.0 1.0 0.7 0.6 0.3 0.1 0.1 0.3 198.2 2.3 0.5 0.1 0.1 0.2 0.9 0.1 3.0 0.4 0.1 0.2 0.4 0.0 0.6 0.1 0.2 61.1 0.8 0.5 0.0 7.6 0.4 0.1 0.1 0.5 0.2 0.6 1.4 0.5 1.4 0.2 0.4 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.1 0.0 0.1 0.6 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.3 0.3 0.1 0.0 0.0 0.4 0.4 0.0 0.6 0.3 0.2 0.1 0.2 0.3 0.0 0.1 0.1 0.0 0.1 2.8 0.9 0.1 0.4 0.2 0.1 0.0 0.1 0.6 0.1 0.3 0.3 0.0 0.0 0.0 0.0 11.4 0.1 0.1 0.1 0.1 0.1 0.4 0.5 0.1 0.0 1.7 0.0 56.9 15.1 2.4 0.0 5.7 0.0 0.0 0.0 0.0 3.4 0.1 0.0 0.0 73.3 0.7 13.6 0.3 0.2 4.4 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.2 0.0 1.1 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.1 0.3 0.7 2.8 0.3 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.1 3.2 2.0 0.4 0.0 9.7 0.2 0.2 0.7 0.1 0.5 15.0 0.0 0.1 2.5 129.6 0.3 0.0 0.1 0.1 0.0 7.7 0.8 0.0 0.0 3.5 0.0 0.0 6.3 0.0 1.0 0.0 0.0 0.0 1.3 0.0 0.4 0.2 1.2 0.7 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.0 2.8 0.0 0.6 0.0 0.3 0.1 HARS1 "HARS, HisRS, USH3B" ENSG00000170445 "Histidyl-tRNA synthetase 1" P12081 5 140673035-140691537 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Neurodegeneration, Neuropathy, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 41.4;dendritic cells: 11.5;Extravillous trophoblasts: 48.6;Hofbauer cells: 35.7;Syncytiotrophoblasts: 36.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036539 Approved Enhanced Cytosol NA NA 190000 "Cluster 27: Non-specific - Gene expression" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA036539: AB_10669796" "unprognostic (9.35e-2)" "unprognostic (9.95e-2)" "unprognostic (1.62e-3)" "unprognostic (1.65e-2)" "unprognostic (2.33e-1)" "unprognostic (8.57e-2)" "prognostic unfavorable (1.96e-7)" "unprognostic (6.50e-2)" "unprognostic (1.46e-1)" "unprognostic (3.82e-2)" "unprognostic (1.28e-2)" "unprognostic (2.40e-1)" "unprognostic (3.46e-2)" "unprognostic (2.99e-1)" "unprognostic (1.25e-1)" "unprognostic (6.26e-2)" "unprognostic (1.36e-1)" 31.6 39.9 64.8 27.1 67.0 24.3 29.3 64.9 88.7 32.9 57.9 39.2 21.8 34.5 27.1 42.9 30.8 21.0 38.3 67.8 72.2 30.7 47.3 27.2 29.6 71.2 69.9 31.3 40.8 37.1 60.0 18.5 72.8 33.0 29.6 18.5 29.2 32.0 56.7 53.9 28.6 35.2 62.1 32.2 36.0 25.6 77.4 32.2 27.1 33.4 36.8 34.3 32.0 71.9 66.8 94.3 55.5 120.5 68.9 74.9 57.9 104.8 75.0 118.6 109.4 174.8 54.1 88.4 90.3 118.3 94.3 66.6 85.9 169.2 111.6 74.5 105.0 63.7 115.4 111.8 86.3 101.1 49.8 80.4 51.5 129.0 72.6 69.5 122.1 52.2 56.5 68.6 125.6 111.0 71.8 100.6 43.3 52.3 60.9 65.4 82.0 70.9 97.0 82.2 86.5 83.7 86.1 121.5 84.2 54.9 89.5 55.5 100.3 107.8 41.6 61.5 144.7 68.5 90.5 89.4 82.8 83.1 76.1 16.2 31.2 24.0 61.0 46.3 54.2 34.9 54.1 57.6 48.5 34.6 58.1 55.4 8.1 59.3 54.9 34.3 51.3 56.7 64.8 67.0 64.9 88.7 67.8 72.2 71.2 69.9 72.8 62.1 77.4 71.9 9.6 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 41.4 11.5 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 48.6 6.1 0.0 0.0 0.0 0.0 0.0 0.0 35.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 36.0 1.7 0.0 0.0 0.0 HDAC7 "DKFZP586J0917, HDAC7A" ENSG00000061273 "Histone deacetylase 7" Q8WUI4 12 47782722-47833132 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 101.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "neutrophil: 6.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 6.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004775 Supported Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA004775: AB_1850548" "unprognostic (3.83e-1)" "unprognostic (9.49e-3)" "unprognostic (1.37e-2)" "unprognostic (4.46e-2)" "unprognostic (6.56e-3)" "unprognostic (2.22e-2)" "unprognostic (2.50e-3)" "unprognostic (1.26e-1)" "prognostic unfavorable (5.16e-4)" "unprognostic (1.28e-1)" "unprognostic (2.07e-1)" "unprognostic (2.38e-2)" "prognostic unfavorable (8.25e-4)" "unprognostic (6.24e-2)" "unprognostic (4.38e-2)" "unprognostic (9.69e-2)" "prognostic favorable (4.65e-4)" 52.5 41.8 7.7 28.5 8.1 23.6 45.3 3.2 9.7 46.2 24.6 44.2 8.9 51.4 13.6 23.5 50.3 16.8 31.6 4.1 4.8 29.3 6.0 55.0 27.3 17.2 7.1 44.9 14.5 20.1 20.6 19.5 10.2 34.4 4.8 2.8 30.6 17.1 16.2 40.1 28.6 16.9 3.4 38.4 27.2 7.9 10.7 80.0 39.2 9.4 15.2 44.3 38.5 7.6 41.6 28.1 28.6 46.9 21.9 60.2 25.3 39.4 30.7 28.3 18.8 37.4 38.4 80.5 126.8 37.1 13.9 37.8 6.7 31.4 10.5 38.8 13.6 27.6 29.9 8.6 23.6 9.1 1.2 39.4 10.8 28.6 15.4 51.6 58.6 45.9 29.9 33.4 18.6 18.0 83.2 21.8 39.4 9.1 29.1 64.2 14.7 29.6 12.1 26.9 8.1 18.8 30.6 14.1 14.4 18.4 13.4 12.0 66.6 56.9 61.0 47.6 28.9 70.8 58.8 67.4 23.8 41.9 19.1 0.0 1.4 0.0 0.8 0.5 0.9 0.8 0.7 0.7 0.4 0.5 0.8 0.6 6.5 0.9 0.5 0.3 0.3 1.5 7.7 8.1 3.2 9.7 4.1 4.8 17.2 7.1 10.2 3.4 10.7 7.6 80.6 41.7 32.1 34.9 32.7 13.8 26.8 28.7 8.6 20.3 22.5 17.4 13.4 28.6 28.6 36.8 0.0 4.8 18.6 5.3 1.9 31.6 15.5 26.2 39.4 79.3 7.3 40.4 19.9 23.0 3.5 37.8 25.5 58.4 8.8 20.2 101.7 2.0 15.6 28.6 17.5 9.6 24.4 32.7 14.1 6.9 55.0 13.3 14.2 46.9 20.5 11.7 28.8 10.6 13.6 66.8 7.3 33.1 42.9 69.1 0.6 3.8 31.8 4.0 26.3 18.3 26.9 1.1 3.7 10.3 21.6 2.9 28.2 9.3 8.1 46.8 HDLBP "HBP, VGL" ENSG00000115677 "High density lipoprotein binding protein" Q00341 2 241227264-241317061 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004189, CAB026457" Enhanced Supported Cytosol NA NA 95000 "Cluster 14: Monocytes - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB026457: , HPA004189: AB_1079044" "unprognostic (2.57e-2)" "unprognostic (1.13e-2)" "unprognostic (2.13e-2)" "unprognostic (1.51e-1)" "unprognostic (4.46e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.58e-5)" "unprognostic (1.70e-2)" "unprognostic (1.71e-1)" "unprognostic (4.45e-2)" "unprognostic (4.39e-3)" "unprognostic (3.92e-2)" "unprognostic (9.48e-3)" "unprognostic (2.47e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (6.39e-5)" "prognostic unfavorable (4.12e-4)" 159.7 135.7 54.9 114.0 62.4 105.4 150.9 54.7 55.0 204.1 169.6 181.9 136.2 138.5 180.0 194.2 212.9 156.1 160.3 59.3 55.3 135.1 247.7 112.8 81.2 67.6 65.4 151.4 603.8 164.1 141.6 176.1 62.1 182.0 171.1 66.8 446.8 143.0 367.6 118.6 136.0 171.8 60.2 79.2 231.6 226.5 78.0 74.7 191.3 365.8 111.1 158.6 98.6 76.0 310.0 239.5 237.4 383.7 587.9 715.3 362.6 736.7 719.9 319.7 451.3 233.1 299.2 93.2 88.1 1039.3 334.0 235.2 356.9 465.8 528.2 150.4 236.0 323.0 305.1 535.7 566.7 233.0 251.4 528.8 369.1 466.0 515.9 500.4 448.1 140.9 310.1 120.0 511.9 309.5 120.4 106.1 237.9 290.4 161.2 111.7 511.9 175.5 255.1 380.1 208.4 223.5 332.3 334.5 278.4 304.2 262.6 201.8 585.4 402.1 255.1 551.5 325.3 136.2 130.8 166.5 488.1 161.1 371.8 26.0 39.3 17.4 15.6 41.0 20.3 19.6 17.7 18.8 41.3 12.7 15.5 15.1 22.0 19.2 58.1 26.4 18.1 27.5 54.9 62.4 54.7 55.0 59.3 55.3 67.6 65.4 62.1 60.2 78.0 76.0 53.9 76.9 102.7 38.5 60.6 70.2 117.4 80.4 150.2 41.0 125.3 98.8 220.5 71.4 124.9 75.4 43.8 133.9 34.7 176.2 135.0 106.7 111.0 152.8 178.3 80.8 96.5 72.6 44.5 122.1 166.5 156.3 203.4 168.2 68.4 199.3 86.7 199.3 94.6 69.0 45.9 291.1 30.5 70.3 66.4 398.0 148.8 75.1 56.9 46.9 77.8 53.5 20.6 46.3 58.1 116.5 118.4 174.9 354.7 203.9 136.3 117.9 163.3 40.0 65.7 126.5 117.0 132.1 120.7 192.4 77.6 215.5 50.7 134.0 163.2 156.1 HDX "CXorf43, FLJ30678" ENSG00000165259 "Highly divergent homeobox" Q7Z353 X 84317874-84502479 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 51.1;Inhibitory neurons: 56.7;Oligodendrocyte precursor cells: 45.8;Oligodendrocytes: 26.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 7.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047189 Uncertain Approved Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA047189: AB_10965463" "unprognostic (7.26e-2)" "unprognostic (3.53e-2)" "unprognostic (1.64e-2)" "unprognostic (1.51e-5)" "unprognostic (3.23e-4)" "unprognostic (5.52e-2)" "unprognostic (1.44e-1)" "unprognostic (6.46e-2)" "unprognostic (1.13e-1)" "unprognostic (1.81e-1)" "unprognostic (6.40e-6)" "unprognostic (1.14e-1)" "unprognostic (7.20e-2)" "unprognostic (3.86e-3)" "unprognostic (2.34e-1)" "unprognostic (1.30e-2)" "unprognostic (3.66e-2)" 1.3 1.6 0.6 0.7 0.9 0.0 1.6 2.9 1.6 1.8 0.0 1.3 0.3 1.8 1.5 1.1 1.6 1.3 1.1 0.8 1.3 1.1 1.0 1.0 0.5 1.1 0.6 2.1 0.5 1.2 1.2 0.3 1.0 1.4 1.1 1.8 1.3 1.5 0.4 0.4 0.7 1.7 0.8 1.0 0.7 1.0 0.6 0.4 1.4 0.4 0.6 1.3 1.0 1.3 0.0 1.5 7.5 0.0 4.4 3.9 0.0 2.3 3.2 5.0 4.9 0.3 0.8 0.0 0.4 1.8 6.2 0.3 0.1 0.5 4.3 0.0 0.3 0.0 1.4 0.0 3.6 0.0 0.0 2.2 0.0 3.1 2.2 3.2 5.4 0.0 0.0 0.0 4.9 0.1 0.0 0.0 4.7 0.0 2.2 0.0 5.7 0.0 2.4 1.0 0.2 3.9 0.0 0.1 0.0 2.7 0.4 0.0 6.4 2.5 1.9 0.8 2.2 0.1 0.0 0.0 1.5 0.0 0.9 0.0 2.3 0.0 0.7 3.5 0.1 1.8 0.2 0.2 3.2 0.5 0.6 0.4 0.0 0.9 3.5 0.3 0.1 0.6 0.6 0.9 2.9 1.6 0.8 1.3 1.1 0.6 1.0 0.8 0.6 1.3 7.8 0.0 2.7 19.2 2.8 2.5 23.1 2.8 5.7 9.4 4.8 5.2 1.9 1.5 3.5 5.5 12.5 0.0 2.7 1.7 0.0 7.0 8.7 2.9 7.1 6.7 7.1 0.4 51.1 1.8 0.0 7.7 2.0 6.6 1.3 4.1 1.8 0.7 1.0 6.7 56.7 1.5 0.0 1.9 3.6 2.1 4.1 4.1 0.0 20.6 3.8 4.1 1.0 45.8 26.5 2.9 1.9 3.4 1.2 12.4 0.5 2.9 1.3 5.3 0.0 8.8 7.5 2.4 0.3 3.0 1.7 0.1 1.5 4.7 1.3 19.6 HECA "dJ225E12.1, HDC, HDCL, hHDC" ENSG00000112406 "Hdc homolog, cell cycle regulator" Q9UBI9 6 139135080-139180802 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 125.8;Langerhans cells: 153.3;Suprabasal keratinocytes: 142.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012581, HPA042313" Uncertain Approved Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA012581: , HPA042313: AB_10796903" "unprognostic (2.98e-2)" "unprognostic (2.39e-2)" "unprognostic (1.48e-1)" "unprognostic (1.40e-1)" "unprognostic (7.31e-2)" "unprognostic (3.38e-3)" "unprognostic (4.29e-2)" "unprognostic (3.27e-1)" "unprognostic (7.39e-2)" "unprognostic (2.00e-2)" "unprognostic (5.77e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (8.09e-4)" "unprognostic (3.47e-1)" "unprognostic (2.59e-1)" "unprognostic (4.72e-3)" "unprognostic (5.77e-2)" 17.2 8.7 10.5 21.5 10.4 39.2 14.2 10.1 13.8 13.8 7.8 12.7 16.5 13.4 6.4 19.3 12.6 13.1 17.4 12.1 11.3 6.4 10.8 19.2 28.8 10.7 11.1 16.7 9.9 9.7 7.0 10.9 12.6 9.5 12.4 3.9 17.9 8.1 20.3 26.1 17.6 13.8 11.9 27.5 12.0 9.5 12.4 31.6 9.6 15.8 25.8 14.2 15.9 14.1 4.8 1.0 9.2 10.5 20.8 19.0 6.8 8.6 14.4 3.8 8.8 1.9 5.3 20.9 12.2 17.9 9.1 7.9 5.6 7.8 7.0 32.9 11.9 10.5 4.6 0.3 6.5 18.6 9.2 21.7 18.8 8.3 10.1 10.4 12.9 13.8 4.5 27.5 7.1 4.9 9.0 15.1 1.7 4.2 1.7 14.0 9.3 10.6 3.3 15.2 8.8 2.6 7.1 19.1 5.5 10.2 4.4 24.4 16.4 6.7 6.3 15.2 7.5 16.4 13.1 18.8 2.4 10.7 3.8 7.0 1.3 2.0 2.8 1.8 3.5 1.5 4.3 3.8 1.0 1.9 4.1 4.1 5.0 1.5 5.5 1.1 3.9 1.4 10.5 10.4 10.1 13.8 12.1 11.3 10.7 11.1 12.6 11.9 12.4 14.1 35.6 6.4 13.9 10.1 38.2 125.8 22.4 15.9 38.7 1.8 29.1 14.4 41.9 8.6 11.6 11.0 2.1 7.3 70.2 53.4 0.0 7.0 12.0 37.8 18.5 34.9 13.1 22.5 20.4 9.8 6.2 22.3 11.7 53.4 13.3 11.7 36.8 13.0 19.1 1.7 23.2 25.5 16.2 84.3 153.3 12.4 15.5 65.7 44.4 38.4 25.7 6.6 29.9 13.0 10.9 14.7 28.4 19.5 48.8 42.4 34.8 4.7 12.3 2.7 52.6 26.4 23.7 12.6 6.7 33.7 142.2 17.4 76.7 10.8 17.2 59.1 HECW1 "KIAA0322, NEDL1" ENSG00000002746 "HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1" Q76N89 7 43112629-43566001 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 16.4;kidney: 7.8" "Cell type enhanced" "Detected in some" "Early spermatids: 135.6;Excitatory neurons: 533.3;Inhibitory neurons: 157.3;Late spermatids: 72.0;Oligodendrocyte precursor cells: 277.9" "Not detected" "Not detected" "Region enriched" "Detected in many" 4 "cerebral cortex: 16.4" "Group enriched" "Detected in some" 4 "basophil: 4.9;neutrophil: 3.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 4.9" "Cell line enhanced" "Detected in some" "A549: 3.8;GAMG: 3.7;U-266/70: 12.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007203, HPA007593, HPA007609" Uncertain Supported Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA007203: AB_2667776, HPA007593: AB_1852305, HPA007609: AB_2117518" "unprognostic (1.40e-1)" "unprognostic (2.85e-3)" "unprognostic (2.57e-1)" "unprognostic (4.39e-1)" "unprognostic (2.43e-2)" "unprognostic (2.80e-2)" "unprognostic (8.65e-4)" "unprognostic (6.93e-2)" "unprognostic (7.30e-2)" "unprognostic (7.31e-2)" "unprognostic (3.43e-2)" "unprognostic (2.67e-2)" "unprognostic (1.43e-3)" "unprognostic (1.64e-2)" "unprognostic (5.23e-3)" "unprognostic (1.89e-2)" "unprognostic (2.42e-2)" 0.1 0.0 1.5 0.2 1.7 0.5 0.2 0.0 16.4 0.1 0.0 0.2 0.0 0.2 0.6 1.0 0.1 1.9 0.0 0.7 0.0 7.8 0.1 0.1 0.4 0.2 0.0 0.3 0.0 0.2 0.0 0.1 0.1 1.3 0.1 2.2 0.4 0.2 0.9 0.6 0.1 0.1 0.0 0.1 0.3 1.8 0.2 0.0 0.5 2.6 0.2 0.3 0.1 3.8 0.0 3.8 0.3 0.5 0.0 0.0 0.0 1.2 2.2 0.1 0.5 0.0 0.0 0.2 2.3 2.2 3.7 0.2 0.0 0.0 0.2 0.1 0.7 0.0 0.3 0.2 0.2 1.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.3 0.0 0.0 0.0 0.0 1.8 0.1 0.7 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.4 0.0 0.0 0.2 0.2 0.0 0.0 0.6 0.8 0.9 0.3 12.0 0.4 0.0 2.7 0.3 0.0 4.9 0.8 0.7 0.3 0.5 0.2 0.6 0.3 0.1 0.1 1.0 0.3 0.3 3.3 0.6 0.6 0.9 0.1 0.0 1.5 1.7 0.0 16.4 0.7 0.0 0.2 0.0 0.1 0.0 0.2 3.8 0.0 0.0 0.0 7.8 0.1 0.4 0.3 0.0 0.0 15.4 0.1 0.3 1.4 0.0 0.0 0.0 4.2 0.0 0.0 0.5 0.0 0.0 135.6 1.1 3.6 0.2 0.0 0.0 533.3 0.0 0.1 0.7 0.0 0.7 0.0 0.0 0.4 0.1 0.0 45.4 157.3 0.1 0.0 0.0 1.4 72.0 0.3 0.2 0.0 24.4 0.1 0.6 0.0 277.9 4.8 0.0 1.4 0.4 0.0 0.4 4.3 15.8 0.0 1.9 0.0 0.6 0.4 3.2 3.3 0.3 0.3 0.0 0.6 0.2 0.5 0.3 HERC3 KIAA0032 ENSG00000138641 "HECT and RLD domain containing E3 ubiquitin protein ligase 3" Q15034 4 88592434-88708541 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "retina: 114.1" "Group enriched" "Detected in some" 9 "Cardiomyocytes: 23.8;Cytotrophoblasts: 7.0;Extravillous trophoblasts: 17.3;Hofbauer cells: 9.3;Syncytiotrophoblasts: 7.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 48.2;hTERT-HME1: 68.6" HPA039170 Approved Supported Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "HPA039170: AB_10673414" "unprognostic (2.21e-2)" "unprognostic (1.65e-2)" "unprognostic (9.28e-3)" "unprognostic (3.24e-1)" "unprognostic (6.26e-2)" "unprognostic (1.88e-2)" "unprognostic (1.30e-2)" "unprognostic (1.85e-2)" "unprognostic (9.77e-2)" "unprognostic (6.51e-3)" "unprognostic (3.48e-3)" "unprognostic (2.58e-2)" "prognostic favorable (5.65e-7)" "unprognostic (1.83e-1)" "unprognostic (3.21e-2)" "unprognostic (1.67e-1)" "unprognostic (1.16e-2)" 11.6 10.2 10.6 13.3 13.4 24.3 14.0 24.5 12.5 13.3 9.4 11.4 11.6 9.9 9.6 16.5 10.2 12.0 21.9 9.6 9.5 14.9 12.1 13.6 17.1 13.6 9.4 12.0 9.3 21.1 9.4 10.1 14.0 19.5 12.1 114.1 12.1 10.9 19.3 18.2 12.1 13.6 7.8 16.1 12.8 3.2 10.0 16.8 14.5 24.4 15.0 11.0 15.3 16.8 12.2 2.4 2.4 3.8 15.3 23.9 9.0 14.5 24.2 13.0 8.5 2.8 14.8 12.0 7.9 48.2 6.1 5.2 4.4 14.1 13.0 7.2 3.4 8.9 6.3 1.9 7.9 22.6 15.7 13.2 15.4 12.7 68.6 8.9 14.2 7.5 7.8 6.2 29.5 3.8 17.8 6.7 0.4 9.6 3.9 19.7 16.5 4.5 8.3 2.6 3.4 3.2 20.4 10.7 4.6 3.9 1.9 12.2 25.7 16.7 9.6 19.9 10.4 11.5 3.1 7.5 11.5 10.2 6.1 7.8 4.9 7.3 3.8 5.6 4.4 4.3 4.7 4.0 5.4 4.2 7.0 4.4 16.2 2.4 9.2 2.4 8.1 2.9 10.6 13.4 24.5 12.5 9.6 9.5 13.6 9.4 14.0 7.8 10.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 17.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 HERC3 KIAA0032 ENSG00000287542 "HECT and RLD domain containing E3 ubiquitin protein ligase 3" 4 88523810-88708450 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 8.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 110.5;Excitatory neurons: 73.2;Inhibitory neurons: 101.6;Oligodendrocytes: 113.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" HPA039170 Uncertain Approved Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA039170: AB_10673414" 1.0 0.9 1.4 1.4 1.2 2.1 1.3 1.9 1.6 2.1 2.1 1.2 0.8 0.9 0.9 1.5 0.8 0.8 2.4 0.9 1.5 1.5 1.3 1.2 1.4 1.8 1.3 1.1 0.6 5.0 1.1 1.8 2.5 1.6 8.5 1.7 1.8 0.9 1.5 0.7 0.9 1.0 1.7 1.2 0.4 1.3 2.1 1.5 1.9 2.1 1.2 1.4 1.9 0.0 0.3 0.5 0.6 4.5 0.5 1.4 4.1 1.8 1.5 0.4 1.4 2.3 0.3 4.6 1.0 0.3 0.0 1.3 1.9 0.4 0.5 1.6 0.1 0.5 0.6 3.4 2.2 1.8 1.9 1.7 5.1 0.9 3.0 0.6 0.7 0.9 3.6 0.0 1.7 0.3 0.0 0.4 0.3 1.8 1.6 0.9 2.3 0.0 0.4 0.7 0.5 0.6 0.8 0.6 0.3 0.5 3.3 1.8 0.7 0.3 2.1 1.4 0.0 0.7 1.5 1.4 0.9 0.0 0.5 0.3 0.3 0.4 0.4 0.3 0.5 0.3 0.6 0.1 0.7 0.8 0.9 0.4 0.7 0.0 0.8 0.4 1.4 1.2 1.9 1.6 0.9 1.5 1.8 1.3 1.8 1.0 1.3 1.4 8.6 6.4 6.9 35.9 15.5 35.9 10.6 7.6 9.6 23.9 11.3 3.8 0.0 5.7 5.5 9.2 110.5 0.0 11.0 14.6 1.9 4.1 3.6 5.2 7.0 7.3 27.6 8.2 73.2 9.1 0.0 8.1 9.2 9.5 15.8 3.4 7.9 13.5 0.0 32.0 101.6 8.9 8.2 22.3 22.0 3.0 8.4 17.9 14.2 68.4 14.1 14.0 8.2 57.3 113.9 10.9 8.2 13.2 12.3 11.6 10.5 9.2 7.2 70.0 6.6 11.1 8.5 3.5 6.7 16.3 50.7 0.0 16.7 4.9 6.1 11.2 HLCS HCS ENSG00000159267 "Holocarboxylase synthetase" P50747 21 36748626-36990236 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ligase, Multifunctional enzyme" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 86.2;Inhibitory neurons: 99.7;Oligodendrocyte precursor cells: 79.9;Oligodendrocytes: 80.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017379 Approved Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA017379: AB_1850768" "prognostic unfavorable (7.72e-4)" "unprognostic (2.41e-1)" "unprognostic (3.93e-2)" "unprognostic (2.05e-1)" "unprognostic (2.75e-1)" "unprognostic (1.44e-2)" "unprognostic (5.08e-2)" "unprognostic (2.67e-1)" "unprognostic (1.54e-1)" "unprognostic (1.03e-1)" "unprognostic (1.31e-1)" "unprognostic (7.44e-2)" "unprognostic (2.43e-1)" "unprognostic (2.55e-1)" "unprognostic (2.67e-2)" "unprognostic (1.85e-3)" "unprognostic (3.02e-1)" 5.0 5.1 4.9 4.2 5.5 3.3 7.4 9.1 5.8 5.1 9.4 4.7 4.2 4.0 7.0 6.1 5.3 4.2 3.7 6.3 5.4 6.4 10.6 4.9 3.7 5.9 4.6 3.8 7.6 10.6 8.8 4.1 6.3 8.9 4.4 6.1 8.5 6.6 13.3 2.8 4.9 4.5 4.1 3.1 5.7 5.7 5.4 3.3 10.7 6.2 4.3 5.4 2.8 5.5 23.8 10.4 13.0 9.6 14.8 13.7 13.3 13.0 12.7 7.1 7.0 10.8 11.0 10.6 6.4 21.4 13.0 8.2 5.9 11.6 5.5 21.0 9.2 16.4 9.6 6.7 14.9 8.6 11.0 10.2 17.0 10.6 23.6 15.5 9.0 12.0 19.7 31.9 17.4 14.2 4.6 5.4 21.8 16.7 11.3 7.1 7.5 11.2 10.8 24.8 8.3 9.9 16.7 8.8 14.8 10.0 16.2 9.1 10.5 9.1 2.7 8.9 7.8 25.6 19.8 7.1 14.6 11.1 10.7 1.9 0.8 0.8 3.6 2.0 2.9 1.2 1.9 2.3 0.8 1.3 2.4 2.2 1.2 4.8 5.1 1.9 1.6 1.8 4.9 5.5 9.1 5.8 6.3 5.4 5.9 4.6 6.3 4.1 5.4 5.5 3.0 9.6 12.5 46.4 4.1 3.3 9.2 5.3 6.8 12.8 9.4 7.4 4.5 8.6 8.4 12.9 22.9 8.9 5.1 3.5 7.9 7.8 5.6 8.0 8.0 3.8 6.0 7.4 86.2 8.1 5.4 5.1 9.7 8.0 5.7 7.9 4.2 18.5 4.6 18.5 99.7 5.2 4.1 5.1 2.1 4.3 4.4 4.0 0.0 45.9 3.2 5.6 8.2 79.9 80.1 9.0 2.9 7.2 4.2 7.8 8.0 6.1 9.2 14.2 0.0 9.0 6.8 5.2 11.5 8.7 4.0 5.1 5.5 11.1 5.4 6.9 HOMER1 "HOMER-1B, SYN47, Ves-1" ENSG00000152413 "Homer scaffold protein 1" Q86YM7 5 79372636-79514134 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.6;skeletal muscle: 34.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 440.0;Inhibitory neurons: 112.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004437, HPA036521, HPA036522" Enhanced Supported Approved Cytosol No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 47: Non-specific - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "CAB004437: AB_627742, HPA036521: AB_2675170, HPA036522: AB_2675171" "unprognostic (2.80e-1)" "unprognostic (5.30e-2)" "unprognostic (4.00e-2)" "unprognostic (5.79e-2)" "unprognostic (8.83e-2)" "unprognostic (6.40e-2)" "unprognostic (2.00e-3)" "unprognostic (2.41e-3)" "unprognostic (2.22e-1)" "unprognostic (3.79e-1)" "unprognostic (3.07e-3)" "unprognostic (3.98e-1)" "unprognostic (7.35e-2)" "unprognostic (9.30e-2)" "unprognostic (1.72e-1)" "unprognostic (2.83e-2)" "unprognostic (2.86e-3)" 2.8 1.3 2.1 2.3 14.0 0.3 2.5 10.6 27.6 3.9 0.0 1.2 0.7 6.7 4.1 4.6 1.7 6.8 20.5 17.9 5.6 5.8 1.7 5.1 1.1 0.0 3.3 3.8 2.2 4.1 2.3 5.4 2.2 1.7 1.0 5.8 1.2 1.7 34.0 2.4 0.8 4.7 0.6 0.8 2.0 5.3 7.4 1.3 15.0 12.9 1.4 8.0 1.7 15.1 14.6 9.8 14.5 23.1 5.4 3.6 33.5 9.0 7.2 9.0 9.6 15.5 9.9 0.2 26.9 7.8 16.2 7.7 18.2 24.5 15.4 2.2 14.3 17.3 3.9 15.7 8.8 8.3 5.4 5.8 15.4 8.1 22.4 3.6 4.3 26.4 21.7 9.3 11.7 20.4 34.8 5.7 24.5 5.2 8.4 22.4 23.8 22.2 9.6 22.3 14.7 8.8 17.2 12.0 9.3 16.0 16.5 7.2 0.7 6.6 16.7 8.0 16.1 4.5 10.8 8.5 18.8 3.3 13.0 0.0 0.0 0.0 0.4 0.0 0.2 0.4 0.1 0.1 0.0 0.3 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.1 2.1 14.0 10.6 27.6 17.9 5.6 0.0 3.3 2.2 0.6 7.4 15.1 4.3 51.3 9.6 21.9 12.1 64.2 28.0 8.5 20.5 24.4 25.6 18.2 95.2 7.2 12.1 16.5 27.1 58.4 20.3 4.3 11.7 4.8 4.7 30.6 24.9 9.5 11.4 0.4 440.0 4.3 44.8 19.3 5.6 39.9 5.7 16.9 4.6 6.9 11.9 52.2 112.1 7.5 10.2 9.6 29.7 5.5 5.6 13.9 21.4 31.9 3.0 4.4 8.2 86.0 19.3 5.5 2.7 8.6 8.9 23.3 3.1 7.0 10.8 8.1 13.1 29.7 19.3 6.9 10.3 23.9 54.8 84.4 9.8 10.2 3.0 25.2 HOMER2 "CPD, Cupidin, DFNA68, HOMER-2, HOMER-2A, HOMER-2B, Vesl-2" ENSG00000103942 "Homer scaffold protein 2" Q9NSB8 15 82836946-82986153 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 226.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 215.9;Endometrial ciliated cells: 184.4;Glandular and luminal cells: 151.9" "Cancer enhanced" "Detected in many" "prostate cancer: 15.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HAP1: 52.7;Karpas-707: 92.6;SCLC-21H: 50.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040134, CAB079014" Uncertain Supported Supported Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 2: Karpas-707 - Immune response" "Cluster 44: Endometrium - Transcription" Cytosol "CAB079014: , HPA040134: AB_10795272" "unprognostic (7.34e-2)" "unprognostic (3.58e-2)" "unprognostic (5.75e-4)" "unprognostic (3.31e-3)" "unprognostic (4.85e-2)" "unprognostic (1.24e-1)" "unprognostic (1.04e-2)" "unprognostic (7.13e-3)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (2.75e-1)" "unprognostic (8.16e-4)" "unprognostic (2.30e-1)" "unprognostic (3.21e-2)" "unprognostic (1.26e-1)" "unprognostic (4.45e-3)" 1.5 6.3 6.5 1.1 7.6 4.6 26.9 8.2 12.8 23.1 69.8 3.2 8.5 8.4 33.7 21.2 25.9 12.8 21.9 16.2 7.8 7.2 46.4 5.3 1.3 5.7 4.6 2.6 226.2 5.1 7.7 0.6 5.7 57.7 1.0 6.4 71.2 4.6 108.7 45.0 1.3 1.4 4.1 4.8 55.4 6.1 6.0 3.0 28.9 55.9 3.6 1.3 11.7 8.0 16.6 6.9 7.2 18.9 0.2 0.1 1.1 1.1 0.0 1.7 0.6 1.2 11.5 0.1 8.8 8.4 8.3 9.1 52.7 24.9 1.2 45.1 33.5 10.6 0.4 8.3 0.7 0.4 32.6 1.8 37.4 0.6 2.1 1.9 0.0 20.6 0.4 92.6 7.0 48.4 3.2 1.1 11.4 1.4 5.1 2.2 11.5 5.5 25.3 20.1 50.8 13.1 18.6 14.1 17.6 5.2 17.1 3.5 0.2 17.2 31.7 1.3 15.3 11.8 5.9 1.8 29.0 0.4 6.4 0.1 0.1 0.4 0.0 0.1 0.0 0.2 0.1 0.0 1.1 0.3 0.1 0.0 0.4 0.0 0.0 0.5 0.2 0.3 6.5 7.6 8.2 12.8 16.2 7.8 5.7 4.6 5.7 4.1 6.0 8.0 1.9 16.0 10.1 24.8 3.8 4.6 56.1 7.2 10.2 15.0 39.7 20.4 23.0 215.9 14.6 11.0 18.8 1.1 4.4 0.3 7.9 29.6 1.9 184.4 15.4 12.4 3.0 8.2 24.8 76.5 0.4 3.6 14.3 151.9 0.0 11.9 1.4 59.6 13.3 20.2 35.1 0.4 0.0 3.2 73.9 4.0 1.8 9.2 37.4 7.5 7.9 18.5 1.0 6.6 11.8 25.9 0.1 0.7 4.1 81.5 0.7 12.1 4.0 5.1 0.0 7.8 4.8 5.5 16.6 19.4 6.0 0.7 3.1 4.1 0.4 30.5 HPCAL4 "DKFZp761G122, HLP4" ENSG00000116983 "Hippocalcin like 4" Q9UM19 1 39678648-39691485 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 91.2" "Group enriched" "Detected in some" 4 "Bipolar cells: 39.2;Distal tubular cells: 11.7;Excitatory neurons: 16.4;Inhibitory neurons: 20.0" "Group enriched" "Detected in some" 11 "glioma: 5.4;thyroid cancer: 4.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 3.0;naive CD4 T-cell: 2.6" "Lineage enriched" "Detected in single" 30 "T-cells: 3.0" "Cell line enhanced" "Detected in some" "Karpas-707: 2.7;SH-SY5Y: 9.1;SK-MEL-30: 2.9;U-2 OS: 1.9;U-266/70: 2.4;U-266/84: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053808 Approved Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Cytosol "HPA053808: AB_2682270" "unprognostic (2.62e-1)" "unprognostic (2.37e-1)" "unprognostic (2.13e-2)" "unprognostic (8.56e-4)" "unprognostic (4.73e-3)" "unprognostic (1.99e-1)" "unprognostic (7.57e-2)" "unprognostic (4.89e-3)" "unprognostic (1.27e-1)" "unprognostic (3.18e-2)" "unprognostic (4.67e-2)" "unprognostic (2.19e-1)" "unprognostic (2.62e-3)" "unprognostic (3.78e-3)" "unprognostic (2.77e-2)" "unprognostic (3.97e-2)" "unprognostic (2.63e-1)" 0.0 10.1 75.1 0.8 89.6 0.4 0.0 38.1 89.3 0.0 0.0 0.3 0.2 0.0 0.3 5.2 0.0 0.2 1.1 91.2 38.0 4.7 0.0 0.6 1.0 16.8 29.8 2.9 4.9 0.2 2.1 0.0 30.1 0.3 0.1 10.9 0.1 0.1 3.2 0.1 0.4 0.0 28.1 0.3 0.6 4.6 58.1 0.2 0.1 1.2 0.8 0.1 0.1 43.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.6 0.0 1.4 0.2 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.8 9.1 0.2 0.0 2.9 0.1 0.0 0.1 0.0 0.0 1.9 0.0 0.0 2.4 3.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.0 3.0 0.5 0.1 0.0 2.6 0.9 0.0 0.0 0.0 0.0 2.2 0.9 75.1 89.6 38.1 89.3 91.2 38.0 16.8 29.8 30.1 28.1 58.1 43.8 0.0 0.0 0.0 4.2 0.0 0.0 0.1 0.0 0.0 39.2 0.1 0.1 1.5 0.0 0.6 1.8 0.0 0.0 0.0 0.0 11.7 0.0 3.4 0.1 0.0 0.1 0.0 0.0 16.4 0.8 0.0 0.6 0.0 0.7 0.0 0.2 0.0 0.0 0.0 1.7 20.0 0.0 0.0 0.0 0.0 1.2 1.2 0.1 0.0 1.0 0.0 4.9 0.0 1.5 1.3 0.2 0.0 1.5 0.3 0.0 0.0 0.1 0.0 1.4 0.0 0.3 0.1 2.8 0.7 0.0 0.0 0.0 0.9 0.1 0.0 0.0 HPRT1 "HGPRT, HPRT" ENSG00000165704 "Hypoxanthine phosphoribosyltransferase 1" P00492 X 134460165-134520513 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine salvage" "Glycosyltransferase, Transferase" "Disease variant, FDA approved drug targets, Gout" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 226.9;Spermatocytes: 213.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006360, CAB012200" Enhanced Supported Cytosol NA NA 9400000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 58: Brain - Synaptic function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol "CAB012200: AB_297217, HPA006360: AB_1079082" "unprognostic (2.02e-1)" "unprognostic (2.18e-1)" "unprognostic (1.46e-1)" "unprognostic (2.32e-3)" "unprognostic (8.55e-2)" "prognostic unfavorable (1.35e-5)" "unprognostic (1.58e-2)" "unprognostic (4.77e-3)" "unprognostic (4.93e-2)" "unprognostic (2.02e-2)" "unprognostic (7.05e-2)" "unprognostic (1.38e-3)" "unprognostic (6.00e-2)" "unprognostic (2.12e-1)" "unprognostic (2.04e-1)" "unprognostic (2.70e-2)" "unprognostic (1.51e-1)" 15.6 26.2 37.3 24.3 39.4 54.7 20.4 26.0 63.7 13.6 22.9 25.5 20.4 14.0 62.7 20.3 16.9 14.6 24.5 40.3 47.1 45.5 45.8 14.5 32.1 31.2 32.1 16.8 37.1 21.9 31.5 16.3 34.7 15.4 23.5 74.1 13.5 16.0 22.6 14.8 26.5 17.3 24.6 16.9 32.2 76.1 31.4 31.3 22.1 17.8 30.6 25.4 13.9 31.3 138.0 64.9 18.0 37.2 39.4 56.1 54.1 71.6 68.7 89.5 116.8 58.7 85.5 154.4 158.7 46.7 106.8 82.0 117.4 98.2 153.4 129.2 219.3 84.0 85.0 60.2 38.9 182.9 74.0 41.6 36.1 80.1 126.4 49.5 104.9 90.3 65.5 3.8 71.0 141.0 141.9 157.0 37.0 160.7 171.8 83.8 91.1 158.6 109.6 65.7 113.0 61.6 51.7 41.5 50.1 48.8 35.5 75.2 52.4 60.5 45.6 175.0 181.5 56.5 105.1 0.9 74.6 199.5 33.8 5.8 21.9 20.4 20.8 36.5 30.0 24.0 30.4 27.6 37.9 24.8 24.8 26.9 5.6 39.4 35.5 15.7 57.4 25.3 37.3 39.4 26.0 63.7 40.3 47.1 31.2 32.1 34.7 24.6 31.4 31.3 32.1 19.2 8.2 11.1 39.6 39.6 55.7 75.6 18.8 38.3 26.4 22.0 23.8 30.0 29.9 57.0 4.2 17.9 28.1 16.8 226.9 50.1 11.9 30.1 28.3 39.2 27.5 101.8 55.3 32.3 30.5 29.5 30.1 41.8 34.9 29.0 20.7 22.2 71.2 25.2 43.1 30.4 63.1 60.7 81.7 32.2 40.7 56.2 55.2 10.3 122.5 37.2 26.8 22.1 30.7 36.6 28.2 26.7 30.9 78.1 24.1 30.2 28.9 78.0 52.6 31.6 39.4 213.5 172.6 40.4 38.8 6.0 53.8 30.2 51.3 46.8 HPS5 "AIBP63, BLOC2S2, RU2" ENSG00000110756 "HPS5 biogenesis of lysosomal organelles complex 2 subunit 2" Q9UPZ3 11 18278668-18322198 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Albinism, Disease variant, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 35.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 96.1" "Cancer enhanced" "Detected in all" "melanoma: 19.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077851 Approved Supported Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 17: WM-115 - Nervous system development" "Cluster 41: Macrophages - Immune response" Cytosol "HPA077851: " "unprognostic (2.25e-2)" "unprognostic (1.97e-1)" "unprognostic (1.07e-1)" "unprognostic (2.59e-1)" "unprognostic (9.85e-3)" "unprognostic (5.89e-1)" "unprognostic (1.47e-2)" "unprognostic (1.55e-1)" "unprognostic (1.61e-1)" "unprognostic (5.20e-2)" "unprognostic (1.51e-1)" "unprognostic (1.59e-1)" "prognostic unfavorable (2.05e-4)" "unprognostic (2.06e-1)" "unprognostic (1.18e-1)" "unprognostic (8.67e-2)" "unprognostic (2.72e-1)" 7.4 8.4 4.4 5.8 5.5 3.7 10.5 4.7 4.5 5.1 5.9 4.8 6.1 5.0 2.8 7.3 5.1 3.9 5.9 4.0 4.6 5.4 35.7 8.6 9.2 5.6 5.0 7.1 6.8 3.6 8.5 7.1 5.9 4.8 3.3 8.9 16.3 3.5 5.5 6.3 8.1 3.9 5.2 9.0 4.6 14.8 5.4 5.9 6.0 3.1 8.3 4.9 5.5 7.4 5.9 8.5 9.0 9.1 11.9 6.6 9.8 15.3 12.6 9.9 10.4 5.3 1.8 14.1 5.8 13.3 12.4 8.3 10.6 10.1 12.1 11.8 7.7 6.9 7.1 6.7 11.2 15.2 12.4 10.6 9.9 6.1 12.9 10.0 8.0 9.0 9.1 8.0 16.1 4.8 8.1 11.0 4.5 6.8 9.3 11.8 12.9 6.0 9.6 5.3 3.0 5.9 19.2 6.8 22.8 8.9 5.1 8.8 5.9 11.3 6.1 14.8 7.1 3.4 12.0 16.1 6.2 7.8 32.4 12.3 3.6 2.9 2.1 5.4 2.6 5.3 2.6 2.2 8.3 4.4 2.5 2.6 1.0 2.8 6.0 3.2 2.6 2.5 4.4 5.5 4.7 4.5 4.0 4.6 5.6 5.0 5.9 5.2 5.4 7.4 17.2 96.1 14.6 13.1 30.8 15.6 14.2 16.2 12.5 17.5 17.4 23.0 18.2 17.2 14.7 7.3 31.3 22.2 16.0 4.7 5.9 5.2 50.9 20.7 11.2 13.4 10.7 11.6 16.7 8.4 10.6 11.8 18.3 30.0 14.5 17.8 7.9 45.1 18.1 10.1 21.0 5.0 12.2 22.7 45.0 18.6 8.4 35.8 28.4 11.2 32.3 16.1 0.0 21.1 24.0 6.2 8.5 13.2 17.4 15.2 27.1 6.5 21.1 26.1 6.6 17.1 13.1 16.2 12.6 19.6 15.3 17.4 17.8 10.5 6.0 21.8 HSD17B1 "EDH17B2, EDHB17, HSD17, MGC138140, SDR28C1" ENSG00000108786 "Hydroxysteroid 17-beta dehydrogenase 1" P14061 17 42552922-42555214 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "placenta: 82.3" "Group enriched" "Detected in many" 4 "Granulosa cells: 1574.2;Syncytiotrophoblasts: 1495.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 8 "BEWO: 399.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021032, HPA065296" Enhanced Supported Cytosol NA NA 19000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA021032: AB_1844345, HPA065296: AB_2685457" "unprognostic (1.13e-1)" "unprognostic (1.40e-2)" "unprognostic (1.68e-2)" "unprognostic (9.25e-2)" "unprognostic (1.73e-1)" "unprognostic (3.88e-2)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (9.35e-2)" "unprognostic (6.04e-2)" "unprognostic (2.88e-5)" "unprognostic (2.17e-1)" "unprognostic (1.30e-1)" "unprognostic (2.60e-2)" "unprognostic (5.09e-1)" "unprognostic (4.98e-1)" "unprognostic (1.32e-2)" 4.4 1.9 3.8 1.7 4.2 0.8 3.0 3.9 4.6 3.0 2.7 2.2 2.1 2.1 0.7 6.0 3.2 0.5 2.1 3.8 3.5 2.4 2.0 1.5 1.0 4.8 3.5 6.8 3.0 0.6 2.4 82.3 4.4 2.6 0.1 0.6 3.7 0.5 4.4 6.3 2.1 0.2 3.2 2.0 2.2 3.8 3.9 0.4 2.8 0.0 0.4 1.7 3.1 6.1 7.0 6.0 1.8 20.2 1.0 0.3 399.0 4.3 0.0 0.0 0.0 2.9 2.8 0.1 4.0 0.2 1.8 9.7 0.7 3.9 0.0 7.6 10.7 3.7 3.8 4.3 0.9 2.7 3.9 0.9 13.2 0.5 2.7 1.5 0.1 2.6 5.7 1.2 0.0 4.8 3.2 2.3 0.4 1.4 2.8 3.9 3.0 2.5 0.5 3.4 4.3 5.6 2.4 41.4 4.2 0.9 48.5 1.1 4.3 2.7 5.4 2.4 2.7 7.7 4.6 1.5 1.9 1.9 2.8 1.0 2.2 2.5 1.1 2.4 1.3 1.2 1.4 1.1 1.3 1.4 1.0 1.0 2.2 1.6 1.5 0.9 0.8 2.0 3.8 4.2 3.9 4.6 3.8 3.5 4.8 3.5 4.4 3.2 3.9 6.1 2.3 0.0 2.2 6.5 2.2 3.1 8.0 14.9 6.2 8.3 11.6 10.7 3.0 4.3 5.3 5.5 12.5 333.0 3.3 4.7 23.5 1.7 1.4 3.3 9.3 4.2 4.2 0.8 1.4 5.6 30.4 11.6 1.5 3.8 2.5 1574.2 3.6 6.4 29.7 10.1 1.6 2.7 8.2 0.6 1.2 1.9 1.8 3.6 1.8 1.9 1.0 11.2 2.1 2.0 3.3 2.0 2.0 3.4 1.4 11.6 2.5 20.5 4.2 8.9 0.0 6.7 29.2 0.8 2.7 14.6 7.4 1495.8 2.6 30.0 2.6 10.4 HSP90AA1 "FLJ31884, Hsp89, Hsp90, HSP90N, HSPC1, HSPCA" ENSG00000080824 "Heat shock protein 90 alpha family class A member 1" P07900 14 102080742-102139699 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Stress response" "Chaperone, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 2527.6" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 12150.7;Urothelial cells: 5781.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002058 Approved Supported Cytosol NA NA 71000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB002058: " "prognostic unfavorable (5.59e-4)" "unprognostic (3.77e-2)" "unprognostic (1.78e-2)" "unprognostic (9.25e-2)" "unprognostic (2.53e-1)" "unprognostic (1.05e-3)" "prognostic unfavorable (3.09e-5)" "unprognostic (7.79e-3)" "unprognostic (5.71e-2)" "unprognostic (7.81e-3)" "unprognostic (3.68e-2)" "unprognostic (1.65e-2)" "prognostic favorable (1.18e-5)" "unprognostic (1.04e-1)" "unprognostic (2.54e-1)" "unprognostic (1.43e-1)" "unprognostic (1.12e-1)" 362.9 439.5 1188.2 299.3 1221.3 459.2 438.6 1272.5 2527.6 282.1 1284.0 289.7 191.3 239.6 318.6 262.0 560.3 363.7 460.6 1213.8 1334.7 452.4 380.5 376.1 321.9 1283.8 1324.0 350.4 273.5 421.8 355.5 420.6 1351.6 348.4 311.1 1127.6 371.1 319.5 405.8 224.8 244.2 306.2 1216.2 217.6 297.5 541.9 1274.3 404.8 223.3 434.9 376.7 406.5 232.8 1639.1 1348.6 1832.2 1142.0 794.2 678.0 567.7 1512.1 1466.0 709.0 1779.5 994.1 1123.6 1245.6 1671.5 1323.1 960.7 1164.7 1471.2 3319.0 1452.5 3215.8 1227.4 1091.9 1291.8 1029.3 1444.3 334.9 1936.9 950.0 539.4 604.6 1140.3 416.2 1107.1 998.6 1764.9 1818.9 838.8 1634.1 1850.8 2087.7 891.1 1191.0 2500.5 1709.3 1968.2 1550.2 715.1 1030.3 1738.2 1497.0 1077.2 1860.4 1389.6 848.2 1903.9 1790.2 765.2 708.2 1234.6 786.5 1860.0 2826.4 783.5 2534.1 2402.7 1167.3 1182.5 1521.0 184.4 87.6 112.1 195.4 128.5 254.9 128.4 162.4 202.2 104.9 127.8 119.2 174.8 57.5 252.6 124.9 208.0 177.8 113.5 1188.2 1221.3 1272.5 2527.6 1213.8 1334.7 1283.8 1324.0 1351.6 1216.2 1274.3 1639.1 1571.4 1137.8 696.7 255.6 934.0 1340.7 12150.7 814.1 748.4 1185.6 1215.2 1173.1 2257.3 684.9 1020.6 513.1 2103.8 1415.1 1091.2 905.8 342.4 1210.5 662.9 2972.0 1350.8 1163.8 947.3 1502.3 158.9 867.6 1909.7 1632.5 788.5 2209.5 916.4 1026.8 341.3 554.4 1348.0 723.5 216.2 992.2 703.9 618.8 3110.7 442.6 732.0 2305.3 1300.2 267.0 773.6 1548.1 356.3 96.5 435.3 779.9 1021.6 722.9 1227.4 3791.1 552.2 896.4 2827.3 3623.6 618.0 1112.4 1974.9 3800.9 2142.4 830.1 1113.7 2050.2 3196.2 972.6 1028.8 5781.1 HSP90AB1 "HSPC2, HSPCB" ENSG00000096384 "Heat shock protein 90 alpha family class B member 1" P08238 6 44246166-44253888 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Stress response" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 4755.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005230, HPA055729, HPA072606, HPA074351" Enhanced Supported Cytosol "Intracellular and membrane" NA Yes 63000000 "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB005230: AB_2121392, HPA055729: AB_2682899, HPA072606: AB_2732203, HPA074351: AB_2732252" "unprognostic (6.12e-3)" "unprognostic (2.96e-3)" "unprognostic (4.72e-2)" "unprognostic (9.24e-2)" "unprognostic (4.20e-1)" "unprognostic (1.15e-3)" "unprognostic (1.76e-3)" "unprognostic (2.74e-1)" "unprognostic (7.97e-2)" "prognostic favorable (4.03e-4)" "unprognostic (1.31e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (9.94e-4)" "unprognostic (3.02e-1)" "unprognostic (9.53e-2)" "unprognostic (2.63e-1)" "unprognostic (1.06e-1)" 584.8 719.5 647.1 368.9 700.4 466.4 507.6 675.2 1529.5 581.3 651.0 425.3 215.8 594.2 540.1 463.8 708.5 332.5 783.8 699.9 811.5 494.6 396.5 526.9 427.7 707.0 738.2 1204.8 722.9 606.0 574.8 451.9 764.3 471.2 389.8 339.5 410.2 491.9 1379.0 483.7 332.6 526.8 655.1 346.0 538.8 251.6 745.8 362.1 456.8 998.8 571.4 525.0 509.4 818.8 2393.2 1495.7 1298.1 1606.0 871.2 904.4 1355.3 1049.1 1021.8 1898.3 1325.5 2254.5 708.0 3029.2 1106.3 1099.8 1928.1 1349.9 3197.5 1563.4 2326.7 1010.5 1292.5 2359.3 793.9 2978.8 628.9 2386.2 1563.2 842.6 1034.9 1495.5 1277.7 1658.4 1847.6 1533.9 3210.4 1095.1 1309.8 2404.3 2003.1 1432.6 1519.7 4378.9 1129.7 1900.7 1325.9 1658.7 1287.7 1422.1 1891.1 1154.8 816.3 1164.8 1526.2 1751.5 1518.6 1178.2 1169.0 1124.0 1875.7 931.1 2440.0 1255.6 2125.8 5370.7 1221.7 1720.8 1312.1 65.9 231.7 52.8 343.7 341.0 577.8 544.0 380.3 395.0 375.1 473.1 509.3 494.0 27.3 434.9 349.0 232.1 326.8 678.5 647.1 700.4 675.2 1529.5 699.9 811.5 707.0 738.2 764.3 655.1 745.8 818.8 1165.2 897.4 678.2 70.5 906.4 1059.3 4755.7 862.6 1331.1 329.3 938.9 1418.3 1407.0 519.0 942.6 366.0 227.2 1104.3 629.3 538.6 729.8 1011.1 185.5 1385.8 1359.6 1070.6 567.4 775.9 103.5 688.9 1107.1 1247.3 616.2 1444.8 1003.4 761.3 360.5 360.3 807.5 339.9 151.0 578.2 518.8 314.5 1262.5 198.4 686.0 896.7 736.4 76.8 573.3 326.1 200.8 69.9 127.4 811.7 504.8 611.2 725.0 1810.6 361.5 664.8 1219.1 262.1 348.4 1512.7 1437.2 266.1 694.1 1232.8 923.5 1123.3 1265.6 1350.0 739.6 2408.7 HSPA5 "BiP, GRP78" ENSG00000044574 "Heat shock protein family A (Hsp70) member 5" P11021 9 125234853-125241382 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Host-virus interaction" "Chaperone, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 1327.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005221, HPA038845, HPA038846" Enhanced Approved Cytosol "Intracellular and membrane" NA NA 790000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB005221: AB_631616, HPA038845: AB_10673477, HPA038846: AB_10673478" "unprognostic (3.98e-2)" "unprognostic (2.50e-3)" "unprognostic (6.64e-2)" "unprognostic (9.60e-3)" "unprognostic (1.54e-3)" "unprognostic (6.02e-3)" "unprognostic (9.08e-3)" "unprognostic (9.11e-3)" "unprognostic (4.50e-2)" "unprognostic (7.45e-3)" "unprognostic (1.49e-1)" "unprognostic (8.96e-2)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.03e-1)" "unprognostic (1.34e-1)" "unprognostic (7.28e-2)" "unprognostic (3.66e-2)" 211.2 170.2 83.7 276.1 91.7 856.2 147.2 101.8 107.3 202.9 112.0 181.6 166.5 183.6 379.1 150.7 177.9 130.6 284.0 90.2 126.8 168.7 327.8 182.8 145.4 105.8 107.0 142.1 260.7 223.3 182.7 311.3 120.2 192.8 183.7 105.1 211.0 167.5 87.6 143.2 175.8 205.2 111.4 129.8 177.9 173.5 101.7 116.2 692.8 85.2 180.0 197.7 105.1 163.9 593.4 380.3 480.2 631.3 505.6 592.0 1152.8 1047.6 728.2 675.9 778.5 558.4 1093.4 649.5 644.7 682.4 1564.0 732.5 403.3 839.4 684.7 403.7 213.8 396.7 392.9 945.1 2692.4 547.4 730.2 363.6 1515.2 551.3 2309.4 728.1 1065.6 129.0 291.9 870.3 482.2 382.6 249.7 297.8 559.1 1327.5 362.2 233.2 492.4 1061.2 608.4 352.7 248.5 448.0 648.1 653.4 1079.3 715.5 694.3 378.0 791.8 439.5 433.0 462.7 484.2 939.0 994.7 551.2 1070.4 435.9 689.0 455.5 366.3 305.3 384.7 361.8 390.0 209.0 276.7 360.1 322.0 173.9 224.6 277.2 280.9 362.9 252.5 349.5 213.6 758.2 83.7 91.7 101.8 107.3 90.2 126.8 105.8 107.0 120.2 111.4 101.7 163.9 227.1 185.9 273.5 38.5 254.0 292.9 1225.2 573.2 192.9 97.3 193.7 166.2 803.4 97.2 416.9 112.2 352.3 505.9 408.7 426.5 45.0 415.0 86.2 372.1 402.2 247.9 508.8 82.3 19.7 258.4 955.2 455.5 258.4 467.4 334.2 304.6 147.4 379.4 449.4 63.9 34.6 508.2 195.3 133.4 271.0 50.3 175.2 261.6 181.5 30.0 135.0 134.6 80.3 29.7 41.1 313.7 408.3 174.5 1041.5 360.8 196.9 121.2 267.6 176.6 118.3 245.9 673.8 435.7 204.3 167.4 236.4 1327.5 323.8 243.0 376.4 795.4 HTATIP2 "CC3, FLJ26963, SDR44U1, TIP30" ENSG00000109854 "HIV-1 Tat interactive protein 2" Q9BUP3 11 20363685-20383782 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Apoptosis, Differentiation, Host-virus interaction" "Developmental protein, Oxidoreductase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 269.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 283.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006417, HPA024321" Approved Supported Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA006417: AB_1079091, HPA024321: AB_1851288" "unprognostic (8.05e-3)" "unprognostic (2.13e-1)" "unprognostic (9.31e-2)" "unprognostic (3.01e-1)" "unprognostic (1.36e-2)" "unprognostic (3.79e-3)" "prognostic unfavorable (2.86e-4)" "unprognostic (1.20e-3)" "unprognostic (1.05e-1)" "unprognostic (4.93e-2)" "prognostic unfavorable (6.18e-4)" "unprognostic (1.75e-1)" "prognostic unfavorable (8.01e-4)" "unprognostic (1.20e-1)" "unprognostic (9.42e-2)" "unprognostic (1.71e-1)" "unprognostic (2.03e-1)" 30.0 57.5 29.6 32.3 35.9 18.6 29.6 33.2 46.1 24.2 34.7 88.4 135.9 13.8 31.4 50.0 13.5 44.8 21.2 29.2 31.3 32.6 97.8 39.1 28.5 34.1 31.7 16.2 26.7 27.8 39.9 28.5 34.6 22.4 80.7 1.9 35.0 20.6 46.2 36.0 121.4 14.4 32.3 38.6 75.4 21.4 32.3 20.2 51.3 21.3 27.4 37.7 35.4 45.8 109.6 177.5 3.9 0.2 52.5 39.4 38.7 46.4 45.8 35.3 41.8 103.2 93.8 24.8 93.1 58.3 136.6 149.7 0.0 28.2 33.9 283.9 21.4 30.8 170.1 0.2 125.3 11.3 139.6 57.3 196.0 28.7 44.5 0.0 102.2 0.0 76.8 31.6 66.3 102.0 0.4 7.0 56.5 193.2 87.1 23.2 0.3 89.8 48.1 60.1 47.2 0.5 150.9 59.1 73.6 18.0 123.7 57.0 125.4 25.1 54.8 51.0 1.2 33.5 44.7 0.6 0.4 76.9 111.4 233.4 133.3 171.1 64.3 126.4 73.4 65.9 74.1 69.2 76.9 76.4 63.9 62.7 304.1 64.5 135.2 23.2 140.9 116.7 29.6 35.9 33.2 46.1 29.2 31.3 34.1 31.7 34.6 32.3 32.3 45.8 49.2 25.6 9.6 3.9 28.0 36.3 60.0 74.2 67.2 1.0 32.9 26.7 11.6 102.9 43.7 47.8 0.0 53.7 16.7 175.6 31.3 91.4 51.1 19.3 6.1 29.5 24.1 28.8 12.9 72.3 118.0 23.8 49.5 34.5 22.9 22.7 33.2 77.5 82.8 3.3 9.1 100.3 105.8 54.0 27.6 59.5 19.9 61.3 44.4 8.4 114.6 9.5 39.1 3.5 40.2 94.7 157.3 9.4 21.4 65.2 269.7 69.0 37.4 1.7 13.1 19.2 28.5 45.5 21.5 87.2 42.1 61.6 33.4 13.2 87.8 62.7 IDO2 INDOL1 ENSG00000188676 "Indoleamine 2,3-dioxygenase 2" Q6ZQW0 8 39934614-40016391 "Metabolic proteins, Predicted intracellular proteins" "Immunity, Tryptophan catabolism" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "liver: 5.4;placenta: 4.0" "Cell type enhanced" "Detected in some" "Early spermatids: 21.0;Endometrial ciliated cells: 18.4;Glandular and luminal cells: 51.3;Late spermatids: 6.9;monocytes: 14.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054911 Approved Cytosol NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 44: Endometrium - Transcription" Cytosol "HPA054911: " "unprognostic (2.00e-3)" "unprognostic (2.34e-5)" "unprognostic (2.22e-3)" "unprognostic (4.41e-3)" "unprognostic (5.37e-2)" "unprognostic (3.69e-5)" "unprognostic (1.19e-1)" "unprognostic (4.73e-3)" "unprognostic (1.20e-2)" "unprognostic (2.78e-1)" "unprognostic (4.11e-3)" "unprognostic (2.25e-1)" "unprognostic (6.47e-7)" "unprognostic (3.25e-2)" "unprognostic (1.96e-3)" "unprognostic (3.35e-2)" "unprognostic (3.08e-3)" 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 5.4 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.1 21.0 18.4 4.4 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.0 51.3 0.0 0.0 0.0 2.6 0.2 0.0 0.4 0.0 0.0 0.0 1.9 6.9 0.3 0.8 0.0 0.0 14.6 0.0 0.0 0.5 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.1 0.1 0.4 0.2 0.0 0.3 0.0 0.4 0.0 0.0 0.1 IFIT1 "G10P1, GARG-16, IFI56, IFNAI1" ENSG00000185745 "Interferon induced protein with tetratricopeptide repeats 1" P09914 10 89392546-89406487 "Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 63.3;Distal tubular cells: 64.6;Muller glia cells: 77.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 66.7" "Group enriched" "Detected in all" 8 "granulocytes: 66.7;monocytes: 21.7" "Group enriched" "Detected in many" 5 "BJ hTERT+ SV40 Large T+: 325.3;BJ hTERT+ SV40 Large T+ RasG12V: 318.1" "CAB045980, HPA053890, HPA055380" Approved Enhanced Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB045980: AB_11125836, HPA053890: , HPA055380: AB_2682800" "unprognostic (1.16e-1)" "unprognostic (2.77e-1)" "unprognostic (1.80e-1)" "unprognostic (7.96e-3)" "unprognostic (1.35e-3)" "unprognostic (2.02e-2)" "unprognostic (6.45e-2)" "unprognostic (3.66e-1)" "unprognostic (3.34e-1)" "unprognostic (8.65e-3)" "unprognostic (1.82e-2)" "unprognostic (7.68e-2)" "unprognostic (2.21e-2)" "unprognostic (2.03e-2)" "unprognostic (5.95e-2)" "unprognostic (9.75e-3)" "unprognostic (6.40e-3)" 17.5 38.0 12.6 4.5 12.4 9.9 14.3 15.2 17.8 17.2 13.0 14.6 3.9 6.9 6.6 5.0 9.5 13.8 22.7 12.4 12.7 23.7 24.9 14.1 3.4 15.1 14.2 9.1 6.1 11.9 20.3 9.9 13.5 6.7 5.0 8.0 42.0 6.2 17.4 4.9 7.5 7.9 29.4 18.7 6.9 5.4 13.9 13.3 9.1 20.6 2.4 7.6 9.4 14.4 10.0 1.2 2.6 17.2 8.1 16.5 0.2 11.7 68.9 325.3 318.1 1.0 10.4 0.7 3.8 14.6 63.4 8.2 1.0 1.0 15.6 0.6 1.1 1.7 8.4 0.9 9.2 1.4 1.7 13.5 0.3 6.2 0.1 6.4 0.4 1.7 0.2 7.7 3.5 0.3 2.3 6.8 0.3 0.1 6.3 3.1 0.8 2.0 7.9 1.2 0.1 0.6 3.1 2.4 69.6 2.4 1.3 1.5 0.5 1.7 1.9 2.5 1.4 1.0 1.3 0.6 2.2 2.3 0.9 9.9 12.6 15.4 1.6 15.6 2.9 3.0 4.1 2.9 3.7 3.2 5.7 3.5 66.7 1.9 21.7 0.2 4.9 6.6 12.6 12.4 15.2 17.8 12.4 12.7 15.1 14.2 13.5 29.4 13.9 14.4 63.3 35.3 5.8 7.2 2.5 2.9 3.3 12.9 3.4 26.4 2.4 5.2 19.1 4.3 7.6 9.2 18.8 4.8 4.7 6.3 64.6 12.6 0.4 21.1 3.2 41.4 0.0 4.0 13.8 5.1 20.8 22.8 0.5 7.2 2.5 11.0 9.3 12.1 36.9 32.0 13.3 1.4 4.1 14.5 3.3 3.0 19.3 13.3 1.8 16.9 13.5 77.9 1.0 12.1 14.4 3.6 4.7 43.6 0.7 1.1 9.8 26.7 17.8 13.4 39.5 18.1 11.4 0.5 3.0 1.0 1.7 1.4 3.1 15.4 0.2 1.2 IFNLR1 "CRF2/12, IFNLR, IL-28R1, IL28RA" ENSG00000185436 "Interferon lambda receptor 1" Q8IU57 1 24154168-24187959 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Antiviral defense" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 17.4;Proximal enterocytes: 18.2;Urothelial cells: 17.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "memory B-cell: 4.9;naive B-cell: 5.9;plasmacytoid DC: 11.3" "Group enriched" "Detected in many" 5 "B-cells: 5.9;dendritic cells: 11.3" "Cell line enhanced" "Detected in many" "U-266/70: 51.4;U-266/84: 19.4;U-698: 40.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA017319 Uncertain Approved Cytosol "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "HPA017319: AB_1851708" "prognostic favorable (5.12e-4)" "unprognostic (7.16e-2)" "unprognostic (8.61e-3)" "unprognostic (8.48e-2)" "unprognostic (8.09e-2)" "unprognostic (1.22e-2)" "unprognostic (7.28e-3)" "unprognostic (2.33e-1)" "unprognostic (5.10e-2)" "unprognostic (1.93e-1)" "unprognostic (5.51e-2)" "unprognostic (4.50e-1)" "unprognostic (3.66e-3)" "unprognostic (5.15e-2)" "unprognostic (1.69e-1)" "unprognostic (2.69e-1)" "unprognostic (1.10e-1)" 0.4 2.2 1.1 2.8 1.2 0.6 2.6 6.2 1.1 1.7 2.2 3.8 5.8 0.9 1.9 3.6 1.8 2.1 3.1 0.8 2.6 3.0 8.4 2.9 7.8 2.5 2.2 1.3 5.0 5.2 5.9 0.3 2.5 3.4 4.0 1.8 4.5 2.1 3.6 7.3 9.2 0.4 1.9 2.8 2.9 1.0 2.7 1.4 4.4 1.3 9.7 2.1 2.3 2.7 6.7 1.3 0.0 0.0 0.0 0.0 1.6 0.0 0.6 1.2 1.0 11.3 1.9 14.3 15.1 0.0 5.4 5.0 6.6 11.6 0.9 3.0 3.5 0.0 2.3 3.4 0.0 0.0 0.0 0.0 3.8 0.3 3.5 2.5 0.0 2.9 0.3 0.0 0.0 1.6 0.2 0.4 14.0 0.5 4.1 0.1 0.0 1.2 2.6 2.8 2.0 1.3 3.5 2.0 1.4 2.4 2.7 0.1 0.0 0.0 2.7 0.0 0.1 51.4 19.4 40.8 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.3 4.9 0.3 1.4 0.0 5.9 0.5 1.4 0.0 0.0 0.0 11.3 0.3 0.5 1.1 1.2 6.2 1.1 0.8 2.6 2.5 2.2 2.5 1.9 2.7 2.7 0.5 0.0 4.8 2.3 5.9 11.1 10.0 4.1 12.5 3.4 1.4 3.2 3.5 2.8 2.3 1.8 0.0 0.6 5.3 17.4 3.9 2.9 2.2 3.4 0.2 0.5 0.0 0.0 2.2 2.3 1.0 0.8 3.1 2.7 0.0 1.5 0.0 8.4 2.3 0.0 2.8 4.1 0.0 0.8 1.9 4.3 0.3 3.0 0.0 2.8 5.5 2.9 0.0 0.5 0.1 2.4 6.1 0.0 12.5 4.3 18.2 2.3 5.1 2.3 0.0 0.0 0.6 0.0 0.7 8.3 12.6 0.3 2.2 0.1 3.3 17.2 IFT122 "FAP80, SPG, WDR10, WDR10p, WDR140" ENSG00000163913 "Intraflagellar transport 122" Q9HBG6 3 129440036-129520507 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein" "Ciliopathy, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 72.8" "Cell type enhanced" "Detected in many" "Early spermatids: 81.7;Late spermatids: 70.3;Spermatocytes: 120.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041815 Uncertain Uncertain Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA041815: AB_10804118" "unprognostic (7.16e-2)" "unprognostic (3.71e-3)" "unprognostic (3.67e-1)" "unprognostic (7.61e-3)" "unprognostic (5.29e-2)" "unprognostic (5.33e-3)" "unprognostic (4.68e-2)" "unprognostic (1.82e-1)" "unprognostic (7.90e-2)" "unprognostic (3.30e-1)" "unprognostic (1.67e-2)" "unprognostic (3.50e-2)" "unprognostic (1.09e-2)" "unprognostic (7.67e-2)" "unprognostic (5.33e-1)" "unprognostic (9.91e-2)" "unprognostic (4.20e-3)" 9.6 7.4 5.7 5.2 7.6 10.1 12.4 6.5 9.2 13.1 15.3 7.6 4.7 12.6 12.7 7.2 24.7 6.7 12.0 6.8 6.8 11.7 9.2 8.8 6.7 4.5 6.2 25.4 13.3 13.9 14.4 10.8 3.0 7.4 6.9 11.2 7.9 8.5 3.9 13.8 5.3 8.9 3.7 4.5 9.0 72.8 7.0 8.9 13.1 2.9 5.7 6.6 8.4 6.3 16.5 24.6 21.0 13.5 29.7 21.0 10.5 8.5 12.9 14.8 14.1 11.9 10.7 10.6 10.0 11.3 14.5 10.4 8.2 7.7 13.3 5.8 8.8 8.2 21.8 10.3 8.1 22.2 7.2 24.7 5.7 11.4 8.8 12.9 20.3 21.8 8.4 22.1 12.1 18.2 18.2 11.6 14.1 12.3 7.0 16.3 8.0 7.7 15.7 3.0 25.9 10.6 24.8 8.2 7.5 7.9 22.6 17.9 9.0 10.1 8.7 13.6 10.2 15.0 11.4 9.3 9.2 11.3 8.1 4.5 3.1 3.7 0.9 2.2 1.6 1.9 1.6 2.3 3.2 2.1 1.8 2.2 1.4 1.5 0.9 0.8 3.0 2.1 5.7 7.6 6.5 9.2 6.8 6.8 4.5 6.2 3.0 3.7 7.0 6.3 7.5 9.6 8.2 28.1 4.3 2.7 5.8 4.5 2.8 9.7 18.0 13.3 6.4 15.7 5.6 25.8 37.5 6.7 4.5 6.2 7.9 5.2 81.7 43.4 11.0 9.7 3.0 7.4 35.1 8.9 5.2 9.8 19.9 10.2 5.1 8.7 20.7 6.0 9.3 5.0 23.1 10.2 4.1 7.2 2.2 70.3 18.6 4.1 3.6 15.0 3.8 11.8 3.1 12.1 15.9 3.4 4.2 13.9 3.4 3.6 6.2 8.2 37.3 21.4 0.0 12.8 7.7 120.4 38.0 5.4 2.8 2.6 4.1 10.6 8.7 3.4 IGBP1 "α4, IBP1" ENSG00000089289 "Immunoglobulin binding protein 1" P78318 X 70133447-70166324 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "B-cell activation" Chaperone "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 342.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000634, HPA001004, CAB034139" Approved Approved Cytosol NA NA 48000 "Cluster 44: Non-specific - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 32: Non-specific - Translation" Cytosol "CAB034139: AB_2295670, HPA000634: AB_1079102, HPA001004: AB_1079104" "unprognostic (3.59e-2)" "unprognostic (5.35e-2)" "unprognostic (2.05e-1)" "unprognostic (5.35e-3)" "unprognostic (1.22e-2)" "unprognostic (1.11e-2)" "unprognostic (4.84e-3)" "unprognostic (2.21e-2)" "unprognostic (1.50e-1)" "unprognostic (2.22e-1)" "unprognostic (1.74e-1)" "unprognostic (3.00e-1)" "unprognostic (2.67e-2)" "unprognostic (1.46e-1)" "unprognostic (5.86e-2)" "unprognostic (1.42e-2)" "unprognostic (4.10e-3)" 56.3 43.2 38.5 29.7 40.3 57.5 55.1 40.3 45.8 68.6 36.9 60.2 57.8 53.3 62.0 46.6 73.5 48.3 53.4 38.6 40.4 57.9 29.4 36.6 59.4 40.4 39.9 119.1 118.6 38.7 35.6 37.6 40.6 42.2 56.2 30.1 64.4 32.1 118.0 63.4 58.3 42.4 41.7 40.7 70.1 18.7 39.7 68.2 57.3 99.9 69.5 52.4 54.5 42.7 42.7 48.9 30.9 35.9 122.2 163.3 44.5 35.6 99.6 47.9 57.1 45.5 55.7 79.1 58.7 62.0 62.6 57.1 73.8 59.1 60.8 31.4 53.2 25.1 52.7 82.9 83.6 59.4 43.9 158.1 143.1 44.3 63.2 166.6 81.8 57.9 51.4 69.5 52.6 42.7 48.7 100.4 37.5 98.0 73.6 42.3 65.0 79.5 77.8 67.2 35.4 43.4 46.3 40.0 87.0 56.4 21.3 61.1 65.8 25.8 40.2 46.0 27.2 65.0 53.7 40.1 36.4 50.5 31.1 51.4 46.1 41.8 34.1 46.0 40.9 50.9 47.4 45.2 51.1 41.8 53.7 48.9 31.4 39.8 39.0 25.6 75.2 48.0 38.5 40.3 40.3 45.8 38.6 40.4 40.4 39.9 40.6 41.7 39.7 42.7 50.1 32.1 54.7 12.1 79.3 100.1 114.2 163.9 82.0 21.5 81.4 82.2 75.8 70.1 85.6 27.6 8.4 123.8 45.3 91.3 103.7 80.3 126.3 58.0 61.1 64.1 69.9 38.9 19.3 143.2 129.0 62.2 46.9 57.9 34.8 90.8 85.3 20.9 82.7 6.7 19.5 128.0 69.2 123.1 89.6 121.5 81.4 75.6 49.8 15.0 119.8 48.9 90.6 13.6 27.6 86.4 153.1 61.7 52.9 70.8 342.0 182.0 57.8 23.6 26.3 62.3 63.0 12.2 25.0 76.2 120.3 124.9 81.9 96.1 128.4 130.4 IGBP1P2 ENSG00000266826 "Immunoglobulin (CD79A) binding protein 1 pseudogene 2" 17 58660424-58692018 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 31 "testis: 8.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000634, HPA001004" Uncertain Approved Cytosol NA NA "Cluster 83: Testis - Spermatogenesis" Cytosol "HPA000634: AB_1079102, HPA001004: AB_1079104" "unprognostic (3.14e-2)" "unprognostic (1.59e-1)" "unprognostic (2.37e-1)" "unprognostic (8.67e-2)" "unprognostic (1.13e-1)" "unprognostic (2.94e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGF2BP1 IMP-1 ENSG00000159217 "Insulin like growth factor 2 mRNA binding protein 1" Q9NZI8 17 48997385-49056145 "Predicted intracellular proteins" "mRNA transport, Translation regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 5.5;testis: 4.8" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 37.3;Spermatocytes: 30.4;Spermatogonia: 21.7" "Cancer enriched" "Detected in many" 16 "testis cancer: 28.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 146.7;CACO-2: 238.7;Hep G2: 112.0;K-562: 124.4;NTERA-2: 117.6;REH: 140.0;SuSa: 111.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021367, HPA062273" Enhanced Supported Cytosol NA NA 13000 "Cluster 28: Placenta - Pregnancy" "Cluster 39: CACO-2 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" Cytosol "HPA021367: AB_1851480, HPA062273: AB_2684733" "unprognostic (6.79e-4)" "unprognostic (2.76e-1)" "unprognostic (4.86e-3)" "unprognostic (2.30e-6)" "unprognostic (1.95e-2)" "unprognostic (9.11e-3)" "unprognostic (1.80e-2)" "unprognostic (1.01e-2)" "unprognostic (9.55e-3)" "unprognostic (2.58e-1)" "unprognostic (2.86e-2)" "unprognostic (5.91e-2)" "unprognostic (2.80e-6)" "unprognostic (2.58e-2)" "unprognostic (1.55e-1)" "unprognostic (2.32e-3)" "unprognostic (1.47e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 59.5 146.7 0.1 5.2 7.6 105.0 8.5 0.2 12.1 20.1 238.7 4.0 12.4 0.9 1.0 3.6 0.0 91.4 0.0 21.1 0.0 52.9 91.3 33.6 112.0 6.9 48.8 23.6 10.4 0.0 2.9 0.2 4.1 24.9 16.6 124.4 0.0 16.6 0.9 0.1 42.9 117.6 0.2 0.2 140.0 48.3 0.0 0.0 0.1 0.0 0.0 5.1 0.1 3.6 111.4 0.2 13.5 0.5 0.0 1.4 12.5 0.0 0.1 0.1 80.7 0.1 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.4 1.1 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.1 5.5 0.0 0.6 0.0 0.0 3.5 0.2 0.0 0.0 0.0 5.3 0.1 0.1 3.9 0.0 2.7 0.2 0.0 37.3 3.7 0.0 0.1 1.3 0.0 0.0 0.0 6.9 0.0 0.2 0.0 0.0 0.0 0.8 4.4 0.3 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 1.1 0.0 0.0 0.1 0.0 5.3 0.7 0.0 0.0 1.1 1.1 30.4 21.7 0.0 0.1 2.9 0.3 0.1 0.0 0.3 IGF2BP2 IMP-2 ENSG00000073792 "Insulin like growth factor 2 mRNA binding protein 2" Q9Y6M1 3 185643130-185825042 "Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA transport, Translation regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 126.6;Glandular and luminal cells: 117.7;Rod photoreceptor cells: 176.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-HME1: 263.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017126, HPA035145" Enhanced Enhanced Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 44: Endometrium - Transcription" Cytosol "CAB017126: , HPA035145: AB_2674491" "unprognostic (7.49e-2)" "unprognostic (1.17e-1)" "unprognostic (1.66e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (2.32e-1)" "prognostic unfavorable (5.12e-5)" "unprognostic (2.46e-3)" "unprognostic (8.25e-3)" "unprognostic (4.17e-1)" "unprognostic (3.45e-2)" "prognostic unfavorable (7.37e-5)" "unprognostic (1.77e-1)" "unprognostic (1.25e-1)" "unprognostic (9.45e-2)" "unprognostic (2.46e-1)" "unprognostic (1.71e-2)" "unprognostic (4.94e-3)" 8.0 9.0 0.9 4.1 1.1 11.9 5.3 6.4 2.0 7.2 1.3 12.6 15.0 5.0 0.7 3.3 11.2 7.5 9.0 1.0 2.1 8.2 1.6 11.7 1.3 2.2 2.1 6.6 4.9 6.4 1.4 15.1 1.3 1.9 14.9 22.3 9.3 1.1 2.0 4.4 16.0 4.6 1.5 4.4 13.2 6.1 1.9 2.2 7.3 3.4 1.8 3.8 5.5 1.2 129.4 11.0 124.2 22.5 64.8 102.5 73.2 68.5 94.2 102.2 121.6 94.1 36.2 0.0 98.2 56.9 130.1 57.7 58.4 97.3 163.9 0.2 58.2 37.7 0.6 64.1 140.2 1.2 0.2 75.0 50.4 67.6 263.9 53.2 95.3 10.1 37.6 0.1 75.2 1.1 0.3 27.8 87.3 22.1 45.7 13.5 48.1 38.8 63.7 0.4 7.7 1.2 5.0 0.2 113.5 120.5 10.1 82.1 144.8 34.8 74.8 44.6 78.2 0.4 0.2 0.3 34.7 0.1 50.3 0.4 1.4 0.2 0.0 1.4 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.1 0.7 1.7 0.4 0.0 0.6 0.9 1.1 6.4 2.0 1.0 2.1 2.2 2.1 1.3 1.5 1.9 1.2 6.2 12.8 11.6 2.3 0.6 19.8 20.1 48.1 1.2 5.2 18.4 6.2 15.7 44.3 49.2 25.8 16.7 2.8 0.9 82.0 3.9 38.9 126.6 86.4 13.8 18.9 35.6 46.9 0.7 25.4 18.0 25.3 20.9 117.7 2.5 64.5 39.7 0.5 16.4 1.7 1.1 44.7 46.8 8.8 16.9 81.7 5.3 10.5 14.2 13.1 11.3 21.2 6.2 4.5 0.2 61.1 80.1 0.4 1.5 63.0 68.8 11.4 74.8 176.7 0.0 2.0 18.8 4.7 14.4 1.2 14.6 6.3 1.1 0.8 45.9 77.8 IGF2BP3 "CT98, IMP-3, IMP3" ENSG00000136231 "Insulin like growth factor 2 mRNA binding protein 3" O00425 7 23310209-23470491 "Predicted intracellular proteins" "mRNA transport, Translation regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 7.3;placenta: 28.9" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 84.8;Early spermatids: 40.8;Extravillous trophoblasts: 93.4;Hofbauer cells: 38.5;Late spermatids: 24.1;Syncytiotrophoblasts: 78.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 170.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA002037, HPA076951" Enhanced Supported Cytosol NA NA 27000 "Cluster 24: B-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "HPA002037: AB_1851483, HPA076951: " "unprognostic (5.72e-2)" "unprognostic (3.12e-1)" "unprognostic (7.25e-2)" "unprognostic (3.56e-3)" "unprognostic (1.45e-1)" "unprognostic (3.00e-2)" "unprognostic (2.64e-3)" "unprognostic (3.18e-2)" "unprognostic (2.60e-3)" "unprognostic (3.67e-1)" "unprognostic (1.02e-5)" "unprognostic (8.76e-2)" "unprognostic (0.00e+0)" "unprognostic (1.43e-1)" "unprognostic (7.95e-2)" "unprognostic (2.87e-4)" "unprognostic (7.51e-3)" 0.3 0.0 0.6 0.8 0.3 0.6 0.1 0.2 0.4 0.1 0.0 0.1 0.0 0.0 0.8 2.1 0.9 0.2 0.0 0.3 0.0 0.0 0.5 0.5 4.2 0.0 0.0 0.0 0.6 0.3 0.0 28.9 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 5.1 0.3 1.6 0.8 0.1 7.3 0.2 0.2 0.1 48.7 14.0 104.5 31.0 16.2 42.8 63.7 8.1 35.7 19.6 24.2 45.0 37.4 36.4 42.1 21.3 86.4 31.2 45.8 35.2 34.2 5.9 18.3 19.3 38.1 37.9 50.3 35.5 13.1 44.1 24.2 15.0 6.3 114.7 170.0 20.0 89.5 0.2 47.8 0.0 21.6 23.5 83.0 36.6 43.3 33.2 34.8 47.1 38.4 4.2 27.4 59.6 4.8 0.3 38.9 118.3 0.0 6.6 68.9 18.6 1.2 40.6 21.0 0.0 15.8 56.7 73.8 38.6 72.8 0.0 0.4 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.6 0.3 0.2 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.0 1.0 2.8 0.3 0.7 0.3 0.0 0.5 0.0 0.0 0.5 0.0 0.3 0.0 0.0 84.8 1.4 0.1 0.0 1.2 40.8 5.4 0.2 1.7 0.0 0.0 2.0 0.2 93.4 3.5 0.0 1.5 3.8 0.1 1.1 0.2 38.5 1.7 12.9 0.0 0.0 0.8 0.6 24.1 2.1 11.3 3.6 5.6 2.9 0.2 2.1 1.5 1.8 1.0 0.0 0.0 2.1 0.2 0.0 0.1 2.6 1.6 0.0 0.4 7.7 6.8 3.5 0.7 0.4 78.5 0.3 0.0 0.0 0.6 IGFL4 ENSG00000204869 "IGF like family member 4" Q6B9Z1 19 46039748-46077118 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "retina: 19.5;skin 1: 6.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 6.2;Cone photoreceptor cells: 14.6;Excitatory neurons: 9.5;Inhibitory neurons: 10.1;Rod photoreceptor cells: 42.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 3.9;HaCaT: 3.5;OE19: 6.1" HPA047655 Approved Approved Cytosol "Secreted - unknown location" NA NA "Cluster 77: Retina - Visual perception" "Cluster 21: OE19 - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol "HPA047655: AB_2680113" "unprognostic (1.22e-2)" "unprognostic (3.37e-2)" "unprognostic (2.57e-1)" "unprognostic (7.96e-2)" "unprognostic (5.48e-2)" "unprognostic (1.03e-1)" "unprognostic (2.39e-1)" "unprognostic (8.25e-2)" "unprognostic (1.63e-1)" "unprognostic (1.62e-1)" "unprognostic (6.33e-3)" "unprognostic (1.09e-2)" "unprognostic (3.59e-4)" "unprognostic (4.30e-2)" "unprognostic (1.12e-1)" "unprognostic (3.38e-1)" "unprognostic (2.85e-1)" 0.0 0.3 1.3 0.1 1.1 0.1 0.1 1.0 2.2 0.0 0.0 0.1 0.4 0.3 1.3 1.0 0.2 0.5 1.0 1.2 0.4 0.1 0.1 0.3 0.4 0.0 0.1 0.9 0.0 0.5 1.6 0.1 0.4 0.4 0.2 19.5 0.5 0.0 0.2 6.9 0.3 0.0 0.0 0.2 0.2 0.3 0.3 0.0 0.8 0.0 0.0 0.3 0.0 1.8 0.0 3.9 0.1 0.2 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.9 0.1 0.5 0.0 0.1 0.5 3.5 0.0 0.0 0.0 0.4 0.6 0.0 0.6 1.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.4 0.0 0.4 0.0 0.3 0.2 6.1 0.2 0.0 1.7 0.9 0.0 0.2 0.2 0.3 0.0 0.1 0.9 0.4 0.2 0.7 0.4 0.3 0.7 0.2 0.2 0.4 0.3 0.1 0.1 0.6 1.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.3 1.1 1.0 2.2 1.2 0.4 0.0 0.1 0.4 0.0 0.3 1.8 0.0 0.0 0.0 2.6 0.0 1.0 0.0 0.8 0.0 6.2 0.1 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 10.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 3.7 0.0 3.5 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.1 0.0 0.0 0.1 0.8 2.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 IGSF1 "IGCD1, IGDC1, INHBP, KIAA0364, MGC75490, PGSF2" ENSG00000147255 "Immunoglobulin superfamily member 1" Q8N6C5 X 131273506-131578899 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 73.4;pituitary gland: 167.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Astrocytes: 3.9;Bipolar cells: 14.0;Breast glandular cells: 5.0;Horizontal cells: 3.3;Melanocytes: 3.6;Skeletal myocytes: 7.2" "Cancer enriched" "Detected in many" 8 "thyroid cancer: 65.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Hep G2: 47.6;SH-SY5Y: 31.2" "Region enhanced" "Detected in all" "hypothalamus: 144.0" "Low region specificity" "Detected in all" "HPA012732, HPA035582" Enhanced Approved Cytosol "Intracellular and membrane" NA NA 100000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 56: Bipolar cells - Visual perception" Cytosol "HPA012732: AB_2732404, HPA035582: AB_2674687" "unprognostic (1.40e-3)" "unprognostic (1.79e-1)" "unprognostic (4.11e-1)" "prognostic unfavorable (4.25e-8)" "unprognostic (1.01e-1)" "unprognostic (2.40e-2)" "unprognostic (1.90e-3)" "unprognostic (2.52e-3)" "unprognostic (8.03e-3)" "unprognostic (9.36e-2)" "unprognostic (5.65e-2)" "unprognostic (1.13e-1)" "unprognostic (1.38e-1)" "unprognostic (5.96e-2)" "unprognostic (1.66e-1)" "unprognostic (2.35e-1)" "unprognostic (5.13e-2)" 1.9 12.5 9.7 0.8 10.0 0.1 2.8 9.7 9.7 3.3 4.8 0.9 0.4 1.2 2.4 1.6 2.5 1.2 12.1 7.5 73.4 0.7 1.5 0.3 0.4 10.0 21.6 1.1 2.6 0.8 167.8 0.7 24.0 4.0 0.4 6.4 2.4 5.7 2.0 1.4 0.6 3.1 7.4 0.3 1.0 12.2 32.4 0.6 4.5 5.1 0.9 0.4 0.9 8.4 0.4 0.6 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 6.0 0.0 0.0 0.1 1.8 0.0 0.0 6.0 0.4 0.0 3.0 47.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.0 4.1 2.8 0.0 0.0 0.0 0.1 0.1 0.2 3.4 31.2 0.0 0.2 0.0 4.1 0.6 0.0 0.0 0.5 0.8 0.0 4.1 1.2 0.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 10.0 9.7 9.7 7.5 73.4 10.0 21.6 24.0 7.4 32.4 8.4 0.2 3.2 0.6 3.9 0.2 0.0 0.5 0.0 1.2 14.0 5.0 1.7 2.3 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.2 0.0 0.0 0.2 0.2 0.3 1.5 0.0 0.1 0.0 0.7 0.7 0.3 0.0 3.3 0.4 0.0 0.0 0.0 0.8 1.1 0.0 0.2 3.6 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.0 0.4 0.0 0.3 0.0 0.8 0.0 0.7 0.0 7.2 0.3 0.1 0.4 0.0 0.4 0.3 0.1 0.0 0.0 0.3 IKBKB "IKK-beta, IKK2, IKKB, NFKBIKB" ENSG00000104365 "Inhibitor of nuclear factor kappa B kinase subunit beta" O14920 8 42271302-42332460 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 135.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001249, CAB004447" Enhanced Supported Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "CAB004447: AB_627785, HPA001249: AB_1079126" "unprognostic (1.04e-1)" "unprognostic (2.30e-2)" "unprognostic (1.31e-1)" "unprognostic (1.73e-3)" "unprognostic (1.26e-1)" "unprognostic (1.27e-3)" "unprognostic (1.95e-1)" "unprognostic (1.25e-3)" "unprognostic (1.75e-1)" "unprognostic (1.55e-1)" "unprognostic (3.27e-1)" "unprognostic (1.73e-1)" "unprognostic (1.20e-2)" "unprognostic (1.89e-2)" "unprognostic (9.20e-2)" "unprognostic (3.02e-1)" "prognostic favorable (1.46e-6)" 9.4 8.2 9.1 4.7 9.8 4.8 8.3 9.2 10.9 7.2 11.7 6.8 4.8 8.1 7.3 10.2 11.6 8.6 5.6 9.2 9.5 6.8 6.6 11.3 12.2 10.5 9.9 6.1 6.2 13.5 4.0 8.2 10.0 7.9 6.8 12.3 8.9 9.3 13.7 11.4 4.9 12.7 9.7 10.5 5.5 3.2 10.1 10.8 9.4 24.3 11.6 11.1 6.8 10.2 6.2 15.7 8.0 13.6 17.3 18.9 5.8 9.2 18.2 15.2 17.2 3.1 13.9 14.1 10.0 16.5 12.5 5.6 8.4 18.3 17.8 9.8 10.8 17.8 7.8 5.9 20.9 6.1 24.0 12.3 13.7 15.0 19.1 36.1 20.7 11.6 12.8 6.9 34.6 5.1 13.9 11.3 6.1 18.9 6.0 11.1 15.3 10.0 19.6 5.7 1.3 4.7 6.4 6.4 11.7 10.0 8.7 23.6 13.6 7.2 3.9 13.9 6.1 2.8 4.0 10.3 13.8 7.6 16.7 7.4 5.0 5.6 4.6 4.1 4.3 4.4 5.1 5.5 3.7 4.8 4.8 4.7 5.2 5.1 5.5 8.5 5.9 2.9 9.1 9.8 9.2 10.9 9.2 9.5 10.5 9.9 10.0 9.7 10.1 10.2 31.3 12.8 26.9 19.2 28.4 24.3 34.1 13.9 25.6 12.7 20.6 15.5 8.8 14.3 15.4 16.5 135.5 10.4 34.1 15.9 1.9 13.4 2.3 13.9 15.6 27.4 11.4 10.1 19.7 13.6 5.3 12.4 21.9 16.5 38.0 24.0 19.6 12.0 18.6 18.5 20.6 16.4 8.2 32.3 24.0 3.4 16.4 23.4 19.6 58.1 33.7 8.7 47.4 17.1 30.2 16.6 15.0 12.8 18.2 31.9 13.2 5.5 20.2 47.9 6.6 13.1 11.4 4.8 7.0 17.8 29.1 15.2 24.3 6.2 14.1 30.8 IKBKE "IKK-i, IKKE, KIAA0151" ENSG00000263528 "Inhibitor of nuclear factor kappa B kinase subunit epsilon" Q14164 1 206470476-206496889 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 37.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 47.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA015788, CAB025983" Approved Supported Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 24: NB-4 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "CAB025983: , HPA015788: AB_1851566" "unprognostic (6.43e-2)" "unprognostic (3.04e-1)" "unprognostic (1.48e-1)" "unprognostic (5.76e-2)" "unprognostic (7.78e-3)" "unprognostic (7.37e-3)" "unprognostic (1.99e-3)" "unprognostic (2.82e-1)" "unprognostic (5.09e-3)" "unprognostic (1.30e-1)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (5.34e-7)" "unprognostic (1.48e-2)" "unprognostic (5.77e-2)" "unprognostic (2.84e-3)" "unprognostic (2.84e-2)" 2.4 3.7 2.6 16.7 4.6 8.7 3.1 2.0 3.2 4.1 1.9 7.8 7.4 1.7 3.9 14.6 2.8 5.1 1.4 2.7 3.3 3.4 1.6 4.1 24.3 4.1 3.6 1.2 3.4 1.0 1.9 2.6 3.9 3.6 7.7 0.1 6.9 2.1 0.5 15.0 8.0 2.5 2.7 14.2 7.2 0.7 4.4 16.5 4.5 0.3 20.4 8.4 6.8 4.6 17.8 13.9 3.7 0.4 6.7 9.2 3.9 7.1 22.3 9.4 10.4 11.5 26.9 35.3 18.6 14.5 11.5 23.0 0.1 18.1 2.2 5.5 3.5 4.7 8.8 7.6 8.4 29.5 14.8 12.2 3.2 7.7 1.7 10.9 14.2 9.4 2.3 10.0 10.5 3.6 19.2 47.7 5.2 4.3 10.9 9.7 4.3 27.7 10.7 29.4 0.0 0.0 2.9 22.9 4.2 4.5 13.8 20.3 26.5 9.0 5.5 6.9 8.5 3.5 1.8 23.3 17.1 24.2 3.7 12.2 32.8 0.6 21.2 23.3 14.8 26.4 32.4 30.1 9.5 14.0 25.7 27.3 2.2 23.9 13.4 3.2 52.8 28.6 2.6 4.6 2.0 3.2 2.7 3.3 4.1 3.6 3.9 2.7 4.4 4.6 0.4 0.0 4.5 0.7 13.7 1.9 3.6 37.8 1.8 0.0 4.3 3.7 0.9 4.3 16.3 0.0 0.0 4.2 7.9 11.7 0.0 12.1 3.3 1.5 0.9 0.7 3.6 4.4 1.5 12.6 5.2 3.4 17.3 2.4 5.1 3.7 2.2 0.8 13.8 0.0 1.5 6.4 8.2 12.9 0.7 7.0 0.9 16.0 7.2 1.9 9.0 0.0 14.4 1.0 0.2 15.9 21.5 0.7 6.4 3.2 10.7 3.5 14.5 0.0 0.0 0.7 3.1 0.3 0.9 11.1 4.8 1.5 15.8 3.9 10.2 11.6 IKBKG "FIP-3, FIP3, Fip3p, IKK-gamma, IP1, IP2, NEMO, ZC2HC9" ENSG00000269335 "Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma" Q9Y6K9 X 154541199-154565046 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "DNA damage, Host-virus interaction, Transcription, Transcription regulation" "Disease variant, Ectodermal dysplasia, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000426, CAB010373" Uncertain Enhanced Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "CAB010373: AB_2124846, HPA000426: AB_1851572" "unprognostic (7.53e-2)" "unprognostic (2.76e-3)" "unprognostic (1.09e-1)" "unprognostic (3.37e-3)" "unprognostic (9.77e-2)" "unprognostic (3.68e-1)" "unprognostic (9.22e-2)" "unprognostic (1.47e-1)" "unprognostic (9.16e-2)" "unprognostic (1.59e-1)" "unprognostic (4.18e-2)" "unprognostic (9.87e-2)" "unprognostic (3.57e-2)" "unprognostic (4.41e-2)" "unprognostic (2.78e-1)" "unprognostic (7.07e-2)" "unprognostic (1.36e-2)" 24.4 32.1 18.0 27.6 19.2 42.5 21.7 18.1 23.8 18.9 16.6 22.1 21.2 24.3 6.2 25.5 19.4 16.0 21.5 17.9 17.3 20.7 62.5 29.7 29.0 22.7 19.3 18.3 18.7 10.8 20.2 11.9 21.6 19.9 10.7 6.3 19.8 13.3 20.0 28.4 26.6 14.1 17.9 41.8 22.6 18.8 20.6 19.7 22.9 9.8 18.7 24.8 21.1 23.6 45.8 46.6 11.2 37.1 22.2 18.2 29.7 28.2 35.1 29.4 43.9 32.2 26.5 35.6 73.5 32.6 79.6 39.8 15.0 27.3 12.0 39.6 25.2 27.5 65.4 54.9 37.4 29.3 92.7 23.4 25.6 39.9 15.8 19.4 33.2 34.6 16.6 34.3 23.5 43.1 29.7 52.9 10.4 32.5 69.2 35.4 16.7 38.4 27.6 27.4 19.5 19.9 32.7 32.9 23.0 8.7 19.4 33.4 36.4 29.8 33.9 70.6 69.9 67.5 49.0 69.2 41.4 50.6 41.3 24.9 34.2 61.3 35.3 42.2 24.1 21.3 21.4 26.5 29.8 20.9 17.1 21.3 50.4 30.7 51.1 25.4 26.8 31.0 18.0 19.2 18.1 23.8 17.9 17.3 22.7 19.3 21.6 17.9 20.6 23.6 16.0 3.2 14.3 8.5 22.3 12.4 12.1 20.6 6.2 6.1 8.0 9.8 6.9 10.0 13.6 12.9 10.4 23.3 27.3 14.0 1.9 18.7 0.9 8.0 10.8 15.3 4.9 9.9 5.5 16.9 16.8 12.6 12.8 9.5 29.2 12.0 10.8 36.4 28.3 25.2 4.8 7.7 14.2 17.2 15.9 2.0 14.3 29.4 12.4 4.7 44.5 11.1 48.4 3.0 11.4 23.4 12.8 13.9 13.7 12.5 10.9 7.6 8.3 10.2 6.6 9.6 13.7 4.6 12.8 10.6 10.5 38.0 24.6 10.2 8.5 14.2 IL10RB "CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2" ENSG00000243646 "Interleukin 10 receptor subunit beta" Q08334 21 33266367-33310187 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Antiviral defense" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 198.4;Extravillous trophoblasts: 164.9;Syncytiotrophoblasts: 315.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020670, HPA047550" Approved Approved Cytosol NA NA 1600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 43: THP-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "CAB020670: , HPA047550: AB_2680086" "unprognostic (8.43e-2)" "unprognostic (6.50e-2)" "unprognostic (5.88e-2)" "unprognostic (1.77e-1)" "unprognostic (1.48e-2)" "unprognostic (7.78e-2)" "unprognostic (1.97e-3)" "unprognostic (1.26e-1)" "unprognostic (5.69e-3)" "unprognostic (1.31e-1)" "unprognostic (1.19e-1)" "unprognostic (6.93e-2)" "prognostic unfavorable (5.62e-9)" "unprognostic (3.09e-1)" "unprognostic (2.76e-1)" "unprognostic (1.29e-2)" "unprognostic (1.05e-1)" 24.6 14.5 8.2 30.3 8.2 19.8 18.1 8.1 11.3 20.2 8.6 40.6 36.5 14.7 9.9 27.6 23.9 23.9 13.8 8.1 7.8 16.8 27.5 25.8 27.6 9.0 8.1 20.4 25.4 10.7 11.3 62.5 8.9 18.6 38.0 4.8 23.6 12.3 12.4 20.2 45.7 19.8 8.6 43.1 33.8 5.0 9.5 30.5 14.0 9.8 26.0 29.3 19.3 9.8 28.8 21.6 4.9 19.1 82.7 61.3 30.0 22.9 62.3 23.5 33.6 20.6 36.1 10.9 25.0 37.8 48.3 34.5 13.2 14.8 17.3 28.5 15.5 30.8 15.1 15.2 58.3 29.5 54.6 62.5 26.8 41.2 23.5 36.8 34.6 25.6 20.6 79.7 32.5 29.1 22.6 27.4 4.2 59.1 11.4 18.5 14.4 33.9 22.6 16.6 7.5 8.0 45.4 35.3 37.5 9.7 21.3 104.5 31.0 24.1 22.7 40.0 12.4 49.9 48.3 6.8 40.5 44.5 19.4 103.8 115.0 98.9 32.0 134.9 35.2 51.6 39.3 38.1 67.9 54.1 36.8 36.3 219.4 56.9 141.6 73.6 77.6 87.5 8.2 8.2 8.1 11.3 8.1 7.8 9.0 8.1 8.9 8.6 9.5 9.8 3.1 35.3 20.5 11.8 26.5 14.5 38.0 54.0 19.4 5.8 3.3 2.8 12.3 32.9 32.3 3.7 14.6 198.4 33.6 102.1 0.0 20.1 1.1 2.3 3.5 23.5 10.2 17.7 14.5 30.1 164.9 24.2 29.6 2.4 35.5 2.1 31.8 23.2 116.6 8.4 12.7 64.4 30.5 111.3 25.3 1.6 31.7 54.3 14.2 23.4 80.6 6.7 49.4 14.6 18.5 23.4 86.8 23.7 39.9 44.3 103.1 1.1 15.8 6.4 19.7 16.9 9.1 2.9 5.0 21.7 14.6 315.6 21.0 0.2 41.4 67.6 IL20RA "IL-20R1, ZCYTOR7" ENSG00000016402 "Interleukin 20 receptor subunit alpha" Q9UHF4 6 136999971-137045180 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 26.4;skin 1: 37.7" "Cell type enhanced" "Detected in many" "Breast glandular cells: 58.6;Endometrial ciliated cells: 110.4;Glandular and luminal cells: 69.8;Muller glia cells: 54.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 9.5;HaCaT: 6.9;OE19: 10.1;RT4: 11.5;SH-SY5Y: 10.8;T-47d: 10.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB024990, HPA042281" Approved Approved Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" Cytosol "CAB024990: , HPA042281: AB_10806235" "unprognostic (3.75e-2)" "unprognostic (8.23e-2)" "unprognostic (1.96e-2)" "prognostic favorable (1.43e-6)" "unprognostic (1.57e-2)" "prognostic favorable (2.29e-5)" "unprognostic (9.87e-3)" "unprognostic (1.64e-1)" "unprognostic (2.43e-1)" "unprognostic (3.78e-1)" "unprognostic (8.03e-3)" "unprognostic (2.18e-1)" "unprognostic (1.85e-6)" "unprognostic (9.38e-2)" "unprognostic (1.88e-1)" "unprognostic (3.09e-3)" "unprognostic (1.64e-3)" 0.9 8.8 3.0 0.7 3.5 0.1 26.4 3.9 2.7 17.1 4.9 4.6 3.1 5.9 4.4 7.0 17.3 4.9 2.4 2.4 3.9 0.4 0.4 5.9 0.0 3.7 4.7 4.9 7.9 2.8 1.6 0.2 4.0 8.6 4.6 4.9 9.7 5.5 0.7 37.7 1.3 3.0 4.3 0.0 6.2 2.0 4.2 1.6 1.1 2.4 2.6 6.0 11.9 3.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.0 9.5 0.0 0.1 1.5 0.1 6.9 1.2 0.1 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.3 10.1 1.4 0.0 0.4 0.0 0.0 11.5 0.7 10.8 0.5 0.0 0.0 0.0 10.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 3.5 3.9 2.7 2.4 3.9 3.7 4.7 4.0 4.3 4.2 3.5 1.4 3.2 26.1 6.2 0.0 21.9 12.0 12.7 6.2 3.5 58.6 39.5 4.6 37.1 22.3 3.7 0.0 2.7 0.5 12.1 0.0 15.3 0.8 110.4 8.0 1.1 7.3 0.0 0.1 0.7 10.6 5.0 19.9 69.8 2.5 0.1 0.4 0.0 0.5 0.0 1.3 23.1 28.5 0.0 1.6 0.9 8.7 0.8 14.2 0.0 0.0 54.6 0.0 3.0 0.3 13.1 11.7 15.1 0.0 18.7 1.7 1.2 36.0 1.3 0.0 2.3 1.7 0.3 3.8 25.3 18.0 8.2 1.3 6.4 12.3 21.1 IL23A "IL-23, IL-23A, IL23P19, P19, SGRF" ENSG00000110944 "Interleukin 23 subunit alpha" Q9NPF7 12 56334174-56340410 "FDA approved drug targets, Predicted secreted proteins" "Antiviral defense, Immunity, Inflammatory response, Innate immunity, Tissue remodeling" Cytokine "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "urinary bladder: 44.5" "Cell type enhanced" "Detected in many" "Ductal cells: 43.4;Ionocytes: 73.2;Langerhans cells: 151.8;Pancreatic endocrine cells: 70.5;Spermatocytes: 41.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "MAIT T-cell: 14.1;memory B-cell: 18.9;memory CD4 T-cell: 25.7;memory CD8 T-cell: 12.5;naive B-cell: 21.5;naive CD4 T-cell: 28.1;naive CD8 T-cell: 17.6;T-reg: 15.6" "Group enriched" "Detected in many" 12 "B-cells: 21.5;T-cells: 28.1" "Cell line enhanced" "Detected in some" "A-431: 15.3;CAPAN-2: 25.6;U-266/70: 42.1;U-266/84: 20.5" "Region enhanced" "Detected in some" "white matter: 3.9" "Not detected" "Not detected" HPA001554 Approved Approved Cytosol "Secreted to blood" NA NA 11000 "Cluster 30: Non-specific - Translation" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "HPA001554: AB_1079135" "unprognostic (2.34e-1)" "unprognostic (1.22e-1)" "unprognostic (1.27e-1)" "unprognostic (1.06e-1)" "unprognostic (5.24e-2)" "unprognostic (4.01e-3)" "unprognostic (4.40e-1)" "unprognostic (1.43e-3)" "unprognostic (1.30e-1)" "unprognostic (6.79e-2)" "unprognostic (3.38e-2)" "unprognostic (4.16e-2)" "unprognostic (3.03e-10)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (1.83e-1)" "unprognostic (4.50e-3)" 0.6 0.3 0.3 2.1 0.2 3.2 0.3 0.1 0.2 0.4 0.1 0.4 0.2 1.0 0.5 4.5 0.4 0.9 0.3 0.4 0.2 0.6 1.1 1.2 4.2 0.3 0.2 0.3 0.7 0.0 0.6 0.6 0.2 0.5 0.3 0.1 1.3 0.2 0.2 0.7 1.9 0.0 0.2 2.2 0.7 4.4 0.3 7.2 0.4 0.0 8.8 44.5 0.5 0.3 15.3 0.3 0.5 0.5 0.0 0.0 1.3 0.3 0.1 0.0 0.0 0.5 25.6 0.9 7.5 0.0 0.8 1.3 0.0 2.5 0.1 1.1 0.5 0.4 0.3 1.2 0.0 0.3 0.9 0.1 0.0 0.0 0.7 3.1 0.0 3.5 0.6 6.2 0.1 0.6 0.6 0.8 2.2 0.3 0.4 0.4 0.2 0.6 8.9 7.4 0.5 0.6 0.3 0.4 1.4 2.1 0.2 7.0 0.5 0.5 0.5 0.4 1.8 42.1 20.5 2.1 0.5 3.7 0.4 0.0 0.4 0.0 2.8 0.0 14.1 18.9 25.7 12.5 0.9 21.5 28.1 17.6 0.2 2.0 0.1 0.1 15.6 10.0 0.3 0.2 0.1 0.2 0.4 0.2 0.3 0.2 0.2 0.2 0.3 0.3 0.5 3.2 2.2 0.0 13.6 3.6 12.1 16.2 0.6 0.0 1.2 1.4 0.4 0.0 23.7 1.8 0.0 0.4 1.5 1.1 1.9 43.4 6.9 11.1 1.0 1.4 0.0 0.0 0.3 7.4 0.5 2.3 1.5 16.6 0.0 0.3 0.0 0.5 2.5 0.0 0.2 1.0 73.2 0.8 151.8 4.2 0.3 14.7 8.8 0.0 34.7 0.5 0.0 0.0 0.3 70.5 0.1 0.7 7.4 6.1 0.4 0.6 15.3 0.5 0.0 0.4 1.4 41.9 6.9 0.6 4.0 0.0 14.4 0.2 2.0 16.3 INHBC ENSG00000175189 "Inhibin subunit beta C" P55103 12 57434784-57452062 "Plasma proteins, Predicted secreted proteins" "Growth factor, Hormone" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 172 "liver: 165.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.6;Hepatocytes: 5.7;Microglial cells: 1.0" "Cancer enriched" "Detected in single" 85 "liver cancer: 22.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 6.4;Karpas-707: 6.3;RH-30: 2.8;U-266/70: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050755 Approved Cytosol "Secreted to blood" NA NA 21000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Cytosol "HPA050755: " "unprognostic (5.26e-2)" "unprognostic (4.58e-1)" "unprognostic (3.43e-3)" "unprognostic (4.08e-3)" "unprognostic (3.76e-1)" "unprognostic (1.98e-2)" "unprognostic (1.03e-2)" "unprognostic (1.10e-1)" "unprognostic (1.34e-1)" "unprognostic (1.23e-1)" "unprognostic (6.10e-2)" "unprognostic (2.48e-2)" "unprognostic (1.68e-4)" "unprognostic (2.90e-2)" "unprognostic (1.52e-1)" "unprognostic (3.55e-3)" "unprognostic (5.05e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 165.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.1 0.1 0.0 0.0 1.0 0.0 0.2 0.0 6.4 0.0 0.4 0.0 0.1 0.0 0.1 0.4 0.0 0.0 1.6 0.0 6.3 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 2.8 0.5 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.3 0.4 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.7 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 INPP5B ENSG00000204084 "Inositol polyphosphate-5-phosphatase B" P32019 1 37860697-37947057 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 47.5;Inhibitory neurons: 48.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028803 Approved Supported Cytosol NA NA 8400 "Cluster 46: Basophils - DNA binding" "Cluster 50: Non-specific - Ribosome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA028803: AB_10612121" "unprognostic (2.28e-2)" "unprognostic (8.91e-3)" "unprognostic (7.67e-2)" "unprognostic (2.27e-1)" "unprognostic (4.30e-2)" "prognostic favorable (1.11e-4)" "unprognostic (1.67e-2)" "unprognostic (1.52e-2)" "unprognostic (4.75e-2)" "unprognostic (1.85e-1)" "prognostic favorable (5.33e-4)" "unprognostic (8.27e-2)" "prognostic unfavorable (6.11e-5)" "unprognostic (1.03e-1)" "unprognostic (2.00e-1)" "unprognostic (2.51e-1)" "unprognostic (1.28e-1)" 13.3 9.3 9.5 10.3 10.7 20.7 11.9 14.7 11.8 16.1 11.5 18.7 6.9 13.9 9.9 7.2 15.7 8.4 12.8 9.2 9.3 10.8 16.2 14.7 18.5 11.5 10.2 23.9 10.5 8.9 11.9 10.4 11.4 10.9 10.0 12.5 8.4 11.1 9.1 10.8 13.4 11.9 9.0 17.3 13.7 7.0 10.5 13.4 12.2 6.0 18.7 16.8 11.7 15.3 6.8 4.6 10.7 15.7 12.3 15.8 18.5 7.5 12.5 9.6 13.2 7.2 9.4 23.2 3.6 12.9 5.0 9.1 14.3 6.0 12.8 16.2 6.3 35.8 15.4 4.9 17.7 19.0 47.4 17.8 3.7 10.2 6.6 9.4 11.0 16.4 11.7 25.6 12.4 5.3 16.7 21.4 15.5 9.5 3.9 18.7 21.3 10.9 5.5 6.2 4.3 6.8 8.8 4.2 18.9 15.7 5.2 15.8 10.6 8.8 7.9 8.5 7.1 20.8 11.8 18.3 10.1 15.8 8.1 27.3 2.9 16.5 7.0 2.3 9.9 7.1 4.8 6.7 6.1 7.6 6.1 5.8 3.7 6.2 6.0 5.4 6.8 4.9 9.5 10.7 14.7 11.8 9.2 9.3 11.5 10.2 11.4 9.0 10.5 15.3 5.7 28.9 26.3 35.3 11.8 2.2 5.8 2.1 4.0 14.7 2.2 2.3 3.2 1.5 6.4 1.8 25.0 4.1 7.9 3.9 0.0 2.4 10.7 2.3 8.4 5.9 3.5 6.5 47.5 4.4 15.4 6.3 16.8 3.3 8.2 6.9 5.3 7.8 5.2 23.5 48.5 5.0 6.1 8.1 5.4 15.9 8.4 8.3 7.2 35.6 11.3 4.6 28.8 20.1 39.4 3.0 4.7 9.1 8.5 4.5 3.5 2.6 5.8 18.9 6.6 7.7 7.1 4.6 8.1 3.4 3.3 4.7 11.2 7.7 4.7 4.1 INPP5D "hp51CN, SHIP, SHIP1" ENSG00000168918 "Inositol polyphosphate-5-phosphatase D" Q92835 2 233059967-233207903 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 50.8;lymphoid tissue: 99.4" "Cell type enhanced" "Detected in many" "B-cells: 94.5;dendritic cells: 95.8;Kupffer cells: 65.6;Microglial cells: 181.8;NK-cells: 193.6;T-cells: 60.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HBEC3-KT: 44.7;HEL: 94.6;HMC-1: 94.8;hTCEpi: 87.1;NB-4: 89.4;THP-1: 62.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016300, HPA070455" Enhanced Supported Cytosol No No 4400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "CAB016300: AB_628250, HPA070455: AB_2686267" "unprognostic (5.29e-2)" "unprognostic (2.05e-3)" "unprognostic (1.99e-2)" "unprognostic (6.71e-3)" "unprognostic (1.10e-1)" "prognostic favorable (2.03e-5)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" "unprognostic (2.29e-2)" "unprognostic (3.74e-1)" "unprognostic (2.56e-1)" "unprognostic (1.23e-1)" "unprognostic (1.14e-2)" "unprognostic (1.66e-1)" "unprognostic (4.82e-2)" "unprognostic (6.58e-2)" "unprognostic (6.54e-2)" 15.5 5.8 6.7 19.8 7.3 32.7 11.4 7.6 6.5 9.2 6.7 9.5 3.7 6.3 2.8 7.5 9.2 6.0 8.2 6.0 8.5 9.5 6.5 25.2 34.1 10.8 9.4 3.2 3.1 1.2 6.9 8.4 11.2 11.8 4.7 0.3 26.3 2.9 3.9 7.9 50.8 3.5 9.3 99.4 6.3 3.5 10.4 14.5 7.8 1.7 31.9 9.8 8.4 10.3 0.1 0.1 0.6 0.0 0.0 0.2 4.8 0.1 0.2 0.1 0.0 0.0 1.2 17.9 0.0 0.0 0.0 0.1 0.0 44.7 0.1 15.4 0.2 94.6 0.1 9.0 0.7 28.7 94.8 1.6 87.1 0.3 9.6 0.3 12.7 2.6 0.4 8.0 0.4 0.0 13.2 89.4 2.9 0.0 0.1 27.5 0.1 6.5 0.1 5.5 0.1 0.1 0.0 1.7 0.0 11.1 0.0 62.9 10.7 0.0 1.5 0.0 0.0 0.2 5.2 26.7 0.1 36.5 0.2 13.2 10.8 11.4 16.0 15.8 10.9 14.0 7.1 12.0 12.3 12.6 5.8 8.4 10.3 12.5 20.0 6.1 10.5 17.9 6.7 7.3 7.6 6.5 6.0 8.5 10.8 9.4 11.2 9.3 10.4 10.3 18.1 3.2 15.5 3.3 94.5 1.7 1.6 5.4 9.1 0.5 3.2 5.8 3.6 4.3 5.2 3.7 0.0 0.6 95.8 1.1 0.0 0.5 13.0 0.8 0.3 20.8 0.0 35.7 2.6 0.5 0.8 1.7 2.0 0.5 15.2 0.1 15.0 2.2 29.2 0.0 1.1 0.2 0.0 65.6 17.1 13.4 0.0 51.5 0.0 181.8 51.4 0.0 193.6 4.0 1.8 0.4 2.5 1.2 34.0 0.6 0.1 0.4 5.7 0.0 0.0 2.0 1.7 0.5 1.0 3.1 1.1 1.1 60.6 0.1 0.5 1.5 INTU "CPLANE4, KIAA1284, PDZD6, PDZK6" ENSG00000164066 "Inturned planar cell polarity protein" Q9ULD6 4 127623271-127726737 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 13.2" "Cell type enhanced" "Detected in many" "Astrocytes: 133.5;Cone photoreceptor cells: 137.6;Endometrial ciliated cells: 81.4;Oligodendrocytes: 78.0;Respiratory ciliated cells: 84.0;Rod photoreceptor cells: 181.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 8.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036714, HPA036715, HPA061467" Approved Uncertain Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "HPA036714: AB_10670238, HPA036715: AB_2675267, HPA061467: " "unprognostic (1.09e-1)" "unprognostic (2.89e-1)" "unprognostic (4.11e-2)" "unprognostic (1.38e-2)" "unprognostic (1.48e-1)" "unprognostic (1.40e-1)" "unprognostic (2.88e-3)" "unprognostic (4.30e-2)" "unprognostic (2.91e-1)" "unprognostic (1.43e-1)" "unprognostic (3.90e-2)" "unprognostic (1.53e-1)" "unprognostic (1.22e-1)" "unprognostic (9.49e-2)" "unprognostic (3.28e-1)" "unprognostic (2.36e-1)" "unprognostic (5.33e-2)" 1.5 1.6 6.0 1.2 5.9 2.6 2.9 4.0 7.0 1.4 4.9 1.2 2.1 2.6 5.1 1.3 2.4 1.5 0.9 4.6 3.2 1.9 0.7 1.6 1.1 1.0 3.1 3.3 1.2 1.1 2.8 1.0 1.3 1.8 1.6 13.2 1.8 1.2 1.1 3.8 1.0 1.3 0.3 1.3 2.1 2.3 6.3 0.6 2.7 2.5 0.7 1.2 1.6 5.9 2.5 1.7 8.7 3.1 1.1 2.7 0.7 1.4 0.7 1.0 1.9 1.2 2.2 1.8 2.1 1.2 2.8 1.5 7.0 1.3 2.9 0.8 2.1 2.6 3.3 3.0 1.1 2.3 1.2 1.2 1.5 2.9 0.7 2.6 2.7 0.9 3.4 2.0 1.4 1.2 0.8 1.2 4.0 0.9 1.6 0.8 2.0 0.5 1.8 1.8 4.1 2.9 2.9 1.6 1.0 4.3 1.8 1.3 2.1 2.5 1.9 2.2 2.0 1.2 1.9 0.6 2.1 1.0 1.5 1.1 0.2 0.1 0.2 0.1 0.2 0.2 0.2 0.1 0.1 0.3 0.2 0.2 1.4 0.3 0.2 0.4 0.1 0.0 6.0 5.9 4.0 7.0 4.6 3.2 1.0 3.1 1.3 0.3 6.3 5.9 8.9 22.4 15.4 133.5 0.6 6.0 10.4 7.2 12.0 56.3 13.7 24.8 15.6 10.0 18.8 3.7 137.6 8.3 0.4 2.7 7.9 7.6 10.2 81.4 30.5 8.2 11.5 3.8 36.0 5.1 6.2 18.7 10.2 15.8 5.1 22.9 6.4 2.5 3.0 37.0 36.6 5.9 10.2 1.6 9.6 11.9 14.0 3.0 7.2 23.4 0.5 16.5 0.0 19.6 78.0 3.4 1.5 11.7 0.0 6.9 1.1 11.2 84.0 181.8 0.0 17.8 10.9 8.7 20.4 7.9 6.1 1.9 1.7 12.9 7.0 6.4 INVS NPHP2 ENSG00000119509 Inversin Q9Y283 9 100099243-100302175 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Calmodulin-binding, Developmental protein" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 132.9;Excitatory neurons: 144.8;Inhibitory neurons: 142.8;Microglial cells: 112.4;Oligodendrocyte precursor cells: 144.3;Oligodendrocytes: 233.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049994 Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 21: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA049994: " "unprognostic (3.84e-3)" "unprognostic (3.11e-2)" "unprognostic (1.74e-1)" "unprognostic (2.86e-2)" "unprognostic (6.73e-2)" "prognostic unfavorable (6.35e-4)" "unprognostic (3.53e-3)" "unprognostic (2.93e-3)" "unprognostic (1.99e-1)" "unprognostic (6.46e-2)" "unprognostic (1.15e-1)" "unprognostic (3.56e-2)" "unprognostic (1.34e-3)" "unprognostic (1.61e-1)" "unprognostic (2.65e-1)" "unprognostic (6.37e-2)" "unprognostic (1.83e-1)" 6.2 6.1 4.2 4.3 7.5 4.6 5.0 7.1 5.4 7.3 7.0 5.6 4.0 7.0 6.3 4.3 5.7 5.4 4.8 4.1 5.6 8.7 9.4 5.2 5.8 6.5 5.5 9.7 4.7 9.7 6.7 5.9 7.1 6.1 4.6 11.8 4.3 5.1 3.6 3.5 4.7 6.1 4.4 5.2 4.4 6.6 6.2 7.8 6.6 4.2 5.7 5.3 5.9 11.6 7.4 13.2 11.0 11.7 13.3 10.7 9.2 8.6 9.0 7.5 6.1 6.7 4.5 17.3 4.9 10.0 13.7 11.1 8.8 11.3 6.1 13.3 6.0 13.0 12.4 7.3 10.0 13.1 10.4 11.2 13.1 7.8 15.8 10.1 13.7 11.7 11.4 10.4 7.8 6.4 10.4 5.1 6.4 13.5 7.6 9.3 19.3 3.9 7.0 6.9 10.0 7.9 9.7 5.8 9.9 8.9 4.1 7.2 10.2 8.7 6.3 9.0 6.5 10.5 13.2 3.5 9.2 5.4 4.8 0.0 1.2 1.9 2.2 0.8 1.9 2.6 1.9 1.2 1.7 2.5 2.4 2.4 0.1 2.5 2.1 1.7 1.2 1.3 4.2 7.5 7.1 5.4 4.1 5.6 6.5 5.5 7.1 4.4 6.2 11.6 5.8 3.2 4.1 132.9 7.1 1.8 7.0 1.5 12.0 4.8 1.7 2.4 2.9 7.2 2.7 0.0 8.4 4.4 5.4 1.4 3.9 2.7 21.5 3.2 7.8 4.8 1.2 6.5 144.8 1.1 3.9 6.0 8.6 3.3 1.3 7.8 1.1 4.0 3.6 6.7 142.8 1.5 2.0 2.2 1.0 35.6 4.7 4.0 0.0 112.4 2.6 2.5 9.2 144.3 233.9 1.5 2.0 3.4 7.4 2.9 2.7 5.8 0.7 5.8 0.0 6.4 4.4 11.0 4.7 5.0 1.6 3.4 6.3 5.3 1.3 4.1 IPO4 "FLJ23338, Imp4" ENSG00000196497 "Importin 4" Q8TEX9 14 24180219-24188869 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 40.4" "Group enriched" "Detected in many" 4 "Early spermatids: 80.5;Late spermatids: 118.0;Spermatocytes: 52.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039043, HPA064572" Uncertain Approved Cytosol NA NA 17000 "Cluster 27: Non-specific - Gene expression" "Cluster 22: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA039043: AB_10673233, HPA064572: AB_2685291" "unprognostic (2.43e-2)" "unprognostic (1.15e-1)" "unprognostic (6.03e-2)" "unprognostic (1.00e-1)" "unprognostic (1.64e-1)" "unprognostic (5.93e-2)" "prognostic unfavorable (8.08e-6)" "unprognostic (9.45e-2)" "unprognostic (2.60e-1)" "unprognostic (5.13e-2)" "unprognostic (6.75e-2)" "unprognostic (9.28e-2)" "prognostic unfavorable (3.20e-4)" "unprognostic (8.59e-4)" "unprognostic (5.45e-2)" "unprognostic (2.18e-1)" "unprognostic (2.15e-2)" 8.9 13.2 1.6 4.7 1.4 4.2 8.0 1.5 1.6 6.9 4.4 7.2 3.2 7.7 2.0 14.0 8.0 1.1 7.8 1.3 2.1 14.1 14.7 6.7 2.8 1.6 1.4 6.9 27.7 2.6 9.4 2.5 1.8 6.8 1.4 0.3 8.7 3.6 21.0 10.7 5.9 1.9 1.4 7.3 8.6 40.4 1.6 2.1 7.0 1.0 1.8 8.7 7.0 2.0 21.9 49.2 6.0 36.0 4.1 8.6 28.4 14.8 6.3 23.5 12.5 39.2 22.4 31.3 16.1 10.6 12.2 25.6 20.4 28.8 2.6 12.1 29.8 20.4 18.6 77.0 8.7 45.4 18.1 7.5 12.3 24.3 6.0 5.3 11.8 15.8 37.5 8.5 15.0 76.6 21.8 21.2 29.1 28.5 41.7 24.4 17.3 23.2 12.6 25.7 29.3 21.1 19.7 31.8 13.9 2.9 27.1 14.7 12.4 22.9 30.8 21.0 32.4 19.8 27.1 34.2 10.8 19.3 31.8 0.0 1.1 0.4 3.3 1.9 3.8 1.8 2.8 2.7 2.4 2.6 2.3 2.9 0.0 2.7 2.4 3.2 1.7 1.9 1.6 1.4 1.5 1.6 1.3 2.1 1.6 1.4 1.8 1.4 1.6 2.0 3.5 0.0 7.9 0.7 4.9 5.9 3.8 5.0 4.6 0.8 11.1 9.7 1.6 8.6 8.7 5.5 4.2 12.1 5.5 3.1 0.0 13.3 80.5 8.3 3.9 5.6 4.2 3.4 1.3 11.0 11.1 4.5 1.1 5.0 0.0 3.1 2.9 5.8 7.9 1.7 1.1 5.9 2.0 2.2 2.6 118.0 5.0 1.3 0.0 0.0 1.7 1.6 2.1 1.0 0.8 6.8 2.5 5.7 2.9 6.1 0.7 11.7 15.1 2.7 6.6 7.0 4.7 52.1 18.8 3.9 6.3 5.9 3.1 6.1 10.4 2.7 IPPK "C9orf12, FLJ13163, INSP5K2, IP5K, IPK1" ENSG00000127080 "Inositol-pentakisphosphate 2-kinase" Q9H8X2 9 92613183-92670131 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 31.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020603 Uncertain Approved Cytosol NA NA "Cluster 13: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA020603: AB_1851853" "unprognostic (3.51e-2)" "unprognostic (4.66e-2)" "unprognostic (6.26e-2)" "unprognostic (1.26e-1)" "unprognostic (3.63e-2)" "unprognostic (2.08e-1)" "unprognostic (4.88e-2)" "unprognostic (3.13e-2)" "unprognostic (4.40e-2)" "unprognostic (1.10e-1)" "unprognostic (2.68e-1)" "unprognostic (1.98e-1)" "unprognostic (6.26e-9)" "unprognostic (1.28e-2)" "unprognostic (4.23e-2)" "unprognostic (2.83e-1)" "prognostic unfavorable (1.28e-4)" 5.4 6.9 5.2 4.5 5.7 8.5 6.4 7.5 6.4 9.1 3.9 4.1 3.2 5.2 4.8 31.6 5.4 4.6 7.8 6.9 4.7 4.4 5.3 4.7 5.7 5.5 5.1 5.4 3.6 8.5 8.1 5.5 5.7 4.2 4.4 5.7 8.8 2.8 7.6 29.8 4.2 5.4 5.0 5.4 4.6 11.6 5.6 5.9 4.6 6.1 8.7 5.7 15.5 5.6 19.3 10.1 9.2 8.0 11.1 8.2 30.4 13.5 8.5 13.6 7.8 6.3 7.4 11.9 6.6 18.9 12.0 27.1 16.4 18.9 11.3 14.9 10.4 9.8 21.9 9.9 7.8 16.7 11.2 8.1 18.4 16.3 12.7 12.4 10.3 9.8 13.5 14.1 13.6 26.3 9.6 7.7 15.8 21.2 14.9 8.5 9.8 4.9 8.0 11.5 19.1 11.2 10.9 44.9 7.8 8.9 10.6 4.2 19.7 10.0 11.3 28.2 14.4 13.0 16.2 6.5 13.0 7.5 9.9 0.0 1.4 3.4 3.6 1.8 4.1 2.4 3.0 3.1 2.1 2.2 2.3 2.6 2.1 0.8 1.9 2.3 4.6 1.9 5.2 5.7 7.5 6.4 6.9 4.7 5.5 5.1 5.7 5.0 5.6 5.6 6.8 3.2 3.4 10.1 4.8 25.4 6.4 7.6 16.5 7.5 6.0 4.7 0.4 1.5 5.1 1.8 6.2 10.8 4.6 5.0 5.9 6.2 11.0 8.3 5.3 6.8 6.7 6.1 23.8 8.0 13.8 4.1 7.1 10.2 0.0 3.6 10.0 3.1 5.1 15.2 23.7 3.5 6.1 7.5 4.6 33.7 3.1 5.3 3.6 7.5 2.8 4.9 8.2 20.6 23.3 9.1 1.4 3.0 6.0 6.4 2.6 3.6 2.6 4.6 6.6 3.9 3.5 20.0 19.4 25.5 29.5 22.8 6.0 4.4 3.7 10.5 IQCH FLJ12476 ENSG00000103599 "IQ motif containing H" Q86VS3 15 67254786-67502260 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 11.5" "Cell type enhanced" "Detected in many" "Astrocytes: 27.4;Early spermatids: 59.4;Excitatory neurons: 26.5;Late spermatids: 37.3;Respiratory ciliated cells: 30.3;Spermatocytes: 48.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040845 Uncertain Approved Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA040845: AB_10672898" "unprognostic (2.69e-1)" "unprognostic (2.94e-3)" "unprognostic (3.11e-2)" "unprognostic (5.89e-5)" "unprognostic (2.48e-1)" "unprognostic (9.83e-2)" "unprognostic (2.57e-1)" "unprognostic (1.18e-1)" "unprognostic (2.64e-1)" "unprognostic (3.25e-1)" "unprognostic (5.37e-2)" "unprognostic (1.70e-1)" "unprognostic (1.51e-3)" "unprognostic (2.81e-1)" "unprognostic (3.81e-2)" "unprognostic (6.16e-3)" "unprognostic (6.42e-2)" 0.3 1.1 0.7 0.3 0.8 0.1 1.6 0.7 1.4 0.9 4.2 0.5 0.2 0.8 2.6 0.5 6.8 0.6 0.9 0.7 1.8 2.2 1.0 0.9 0.4 2.5 2.2 0.3 0.7 3.7 2.0 0.4 1.6 0.6 0.7 5.0 0.6 0.8 0.5 0.6 0.1 0.3 2.0 0.4 1.1 11.5 1.9 1.0 4.1 0.0 0.2 0.7 0.3 1.4 1.7 1.6 0.8 1.3 1.1 2.6 0.6 0.9 0.7 1.3 0.9 0.1 1.9 1.2 0.8 1.5 1.5 2.8 2.6 1.0 2.3 0.2 1.2 0.3 1.6 0.2 1.7 0.5 0.3 1.7 1.1 2.9 2.8 1.3 0.5 3.1 2.6 1.1 1.0 1.8 0.4 0.4 0.9 1.0 1.1 0.3 1.2 1.3 1.6 0.7 2.6 0.7 1.2 1.6 4.8 1.6 4.3 0.3 1.2 1.5 0.7 2.4 1.0 2.5 3.2 0.3 3.1 1.3 1.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.7 0.8 0.7 1.4 0.7 1.8 2.5 2.2 1.6 2.0 1.9 1.4 0.7 3.2 1.1 27.4 0.3 1.3 1.0 1.6 1.8 1.5 2.7 2.2 1.1 0.0 2.8 1.8 8.4 0.2 0.3 0.4 0.0 1.0 59.4 15.9 1.1 0.9 0.0 0.4 26.5 0.8 0.5 0.7 8.2 2.0 0.0 0.7 0.0 0.0 0.3 1.7 18.2 0.5 4.1 0.0 0.7 37.3 0.9 0.3 0.0 8.4 1.0 1.1 0.0 9.0 9.5 0.7 0.0 0.7 0.5 0.3 0.2 2.2 30.3 5.4 0.0 1.5 0.6 48.8 18.2 1.2 0.4 0.3 0.4 4.2 0.4 1.0 IQCJ-SCHIP1 ENSG00000283154 "IQCJ-SCHIP1 readthrough" B3KU38 3 158962235-159897366 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 165.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 7.3;Basal squamous epithelial cells: 12.5;Bipolar cells: 11.5;Excitatory neurons: 11.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "HPA003243, HPA003445" Approved Approved Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA003243: AB_1079877, HPA003445: AB_1079875" 22.0 5.1 82.3 9.7 90.6 2.2 15.4 84.9 165.9 9.2 56.6 49.8 4.5 19.6 6.3 15.4 18.2 12.5 57.2 83.9 73.9 17.8 14.3 19.6 2.2 93.5 88.0 4.4 2.7 1.1 7.3 23.6 92.0 17.7 6.8 14.2 6.5 20.4 27.6 5.7 12.8 25.9 81.5 4.3 18.3 4.7 87.2 2.5 5.7 3.2 1.8 35.8 10.8 110.5 87.9 14.8 28.9 34.4 6.6 6.3 25.1 73.6 17.3 59.4 40.5 55.6 20.9 4.4 46.4 24.6 22.6 34.8 11.3 24.9 48.5 72.7 27.6 0.1 31.2 2.8 7.7 4.2 0.5 6.5 20.8 26.5 31.1 49.3 44.5 4.9 0.0 0.3 27.7 3.9 0.3 0.0 24.2 7.0 31.9 10.2 58.4 0.0 57.6 4.7 5.8 26.8 39.8 16.7 21.8 32.9 9.8 0.8 37.6 34.0 47.5 22.9 101.5 0.3 0.5 0.4 19.1 12.4 92.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 82.3 90.6 84.9 165.9 83.9 73.9 93.5 88.0 92.0 81.5 87.2 110.5 4.7 6.4 0.0 1.0 0.1 1.5 7.3 0.8 12.5 11.5 0.3 0.9 0.6 0.0 1.4 1.8 6.2 0.0 0.1 0.3 0.0 0.9 2.0 2.1 0.8 5.7 0.0 0.0 11.3 0.6 0.0 3.1 0.0 2.3 2.5 0.0 1.8 0.6 0.0 0.0 4.7 0.2 0.0 0.3 1.2 0.6 0.3 1.2 0.0 0.0 0.6 0.5 0.0 0.0 0.6 1.2 0.0 1.2 0.0 1.3 0.0 4.2 2.4 0.6 0.0 2.5 5.4 0.1 0.4 3.5 0.9 0.0 0.5 0.0 0.2 1.6 IRF3 ENSG00000126456 "Interferon regulatory factor 3" Q14653 19 49659569-49665875 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004895, CAB013018" Approved Supported Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "CAB013018: AB_2533904, HPA004895: AB_1851887" "unprognostic (5.75e-2)" "unprognostic (1.46e-2)" "unprognostic (1.26e-3)" "unprognostic (1.59e-1)" "unprognostic (9.17e-2)" "unprognostic (9.60e-2)" "unprognostic (7.85e-3)" "unprognostic (7.91e-2)" "unprognostic (6.98e-2)" "unprognostic (5.52e-2)" "unprognostic (5.02e-2)" "unprognostic (3.85e-3)" "prognostic unfavorable (1.56e-7)" "unprognostic (1.61e-2)" "unprognostic (4.98e-1)" "unprognostic (3.47e-2)" "prognostic favorable (3.61e-4)" 32.9 33.7 27.9 20.8 27.4 24.9 33.8 27.4 36.0 46.5 27.8 39.0 18.8 37.0 10.2 37.3 39.7 19.5 31.8 26.4 27.4 46.3 42.4 39.7 42.6 28.3 27.2 44.1 36.6 12.1 37.0 21.1 28.7 46.7 11.4 5.8 34.7 22.8 18.0 43.5 53.0 14.4 27.9 73.9 38.3 16.0 29.7 29.9 43.0 9.4 24.2 40.2 41.1 28.2 82.2 88.3 30.1 44.7 22.6 35.3 68.1 35.1 52.8 59.8 77.7 62.6 93.8 47.7 39.4 32.9 49.8 66.2 32.5 91.0 26.1 66.0 57.6 44.7 33.8 58.2 25.5 33.1 43.9 33.9 63.6 79.2 23.8 30.5 47.9 60.9 50.4 50.7 32.3 79.9 53.4 94.2 36.0 82.3 80.7 60.8 29.4 83.8 43.7 69.2 16.7 21.7 64.5 69.6 35.9 29.5 30.6 64.4 33.6 35.0 32.7 26.7 46.0 69.4 76.9 47.9 40.1 77.2 35.7 25.4 27.6 50.3 58.6 29.3 52.8 37.8 57.1 55.0 22.0 37.9 49.5 45.2 35.1 46.3 36.0 30.2 81.0 39.5 27.9 27.4 27.4 36.0 26.4 27.4 28.3 27.2 28.7 27.9 29.7 28.2 42.5 25.6 33.9 16.0 51.3 54.2 35.6 58.4 29.0 33.0 40.1 39.2 7.9 35.8 51.9 40.5 29.2 78.2 57.6 83.6 19.6 39.4 3.7 30.4 29.5 33.1 44.9 40.0 3.9 46.5 92.0 30.4 76.0 37.0 77.3 33.8 38.6 25.7 39.0 16.8 5.6 70.5 46.8 32.2 29.9 8.9 41.0 33.9 30.2 10.3 71.1 37.9 122.6 7.1 10.8 46.8 60.0 35.7 70.4 26.7 74.8 25.8 45.4 47.7 32.9 23.1 28.2 13.7 15.9 23.2 45.6 49.3 69.2 30.9 63.8 30.1 IRF9 ISGF3G ENSG00000213928 "Interferon regulatory factor 9" Q00978 14 24161265-24166565 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Antiviral defense, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 73.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 76.6;BJ hTERT+ SV40 Large T+ RasG12V: 58.9;GAMG: 48.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001862 Approved Supported Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 52: Non-specific - Transcription" Cytosol "HPA001862: AB_1079153" "unprognostic (4.96e-3)" "unprognostic (4.91e-2)" "unprognostic (6.84e-3)" "unprognostic (8.17e-3)" "unprognostic (5.32e-2)" "unprognostic (2.51e-2)" "unprognostic (2.00e-1)" "unprognostic (1.77e-2)" "unprognostic (4.50e-1)" "unprognostic (9.10e-2)" "unprognostic (4.08e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (7.58e-8)" "unprognostic (1.56e-1)" "unprognostic (4.44e-2)" "unprognostic (4.40e-2)" "prognostic favorable (9.92e-4)" 25.2 27.1 16.0 25.0 17.4 25.4 22.5 16.3 15.9 31.6 13.3 29.3 17.6 27.7 13.1 21.8 25.0 24.2 19.1 14.7 17.9 29.1 25.9 28.2 25.2 22.0 17.9 25.0 14.1 11.6 22.1 12.8 17.5 22.1 9.9 3.6 36.4 12.7 9.0 20.7 26.8 17.6 22.2 48.5 25.3 8.3 18.0 22.7 22.8 8.8 20.4 27.0 22.5 21.2 3.9 2.4 2.5 0.9 15.9 17.6 1.6 7.3 37.5 76.6 58.9 5.2 22.5 5.0 7.7 20.3 48.5 6.0 1.6 1.5 19.3 24.3 0.0 11.6 2.1 6.1 25.3 1.1 14.2 17.2 5.3 9.1 1.9 15.1 8.3 1.0 1.7 32.6 10.0 4.5 2.0 4.8 0.4 2.8 7.4 0.8 2.5 3.0 17.2 2.6 0.4 2.6 6.6 3.5 38.9 5.1 1.1 9.7 16.1 8.1 5.7 4.8 1.7 32.4 24.9 4.7 9.4 1.8 7.3 197.2 80.5 112.3 73.4 103.1 58.1 93.3 72.4 62.0 61.7 88.7 64.0 58.4 202.8 74.8 103.9 75.1 103.0 103.4 16.0 17.4 16.3 15.9 14.7 17.9 22.0 17.9 17.5 22.2 18.0 21.2 37.9 25.6 15.1 21.2 22.8 2.3 8.6 6.1 6.2 6.6 8.0 10.3 0.2 10.0 9.7 5.5 8.4 1.5 32.0 6.1 0.0 4.9 0.2 9.0 19.4 21.0 1.8 7.4 5.0 5.5 21.9 14.8 20.9 9.4 24.6 42.0 11.0 1.7 7.0 8.4 4.9 5.3 10.2 8.2 8.0 1.0 12.8 13.4 5.4 26.2 13.4 11.2 73.2 32.2 9.5 6.2 10.9 6.8 13.2 8.4 21.8 2.6 32.3 4.3 13.1 33.7 15.1 1.3 1.7 3.7 2.7 1.6 26.1 24.9 4.9 12.4 ISCU "hnifU, ISU2, NIFUN" ENSG00000136003 "Iron-sulfur cluster assembly enzyme" Q9H1K1 12 108562582-108569368 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1430.2;Late spermatids: 969.5;Proximal tubular cells: 1315.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006329, HPA038602, HPA057592" Approved Supported Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "CAB006329: AB_425907, HPA038602: AB_2676109, HPA057592: AB_2683478" "unprognostic (1.72e-1)" "prognostic favorable (4.90e-7)" "unprognostic (1.53e-1)" "unprognostic (3.53e-1)" "unprognostic (2.43e-1)" "unprognostic (3.15e-2)" "unprognostic (1.33e-1)" "unprognostic (6.69e-3)" "unprognostic (1.14e-1)" "unprognostic (1.84e-1)" "unprognostic (1.28e-3)" "unprognostic (2.49e-2)" "prognostic favorable (2.73e-7)" "unprognostic (2.03e-1)" "unprognostic (1.33e-1)" "unprognostic (1.37e-3)" "prognostic favorable (6.12e-4)" 174.8 387.6 186.3 89.8 187.5 98.2 166.8 209.9 216.8 174.4 222.2 222.9 88.8 170.2 148.8 91.2 142.5 106.5 507.1 186.2 223.0 341.3 119.9 138.3 138.9 223.4 192.5 169.2 106.2 286.0 228.9 111.1 214.4 150.5 112.0 58.9 123.7 196.1 422.3 111.6 142.7 122.2 187.0 163.9 169.2 123.2 188.0 151.6 184.4 381.5 138.3 179.0 133.4 177.0 47.5 113.8 78.9 47.3 277.4 211.6 191.7 92.8 152.2 69.7 65.7 84.9 66.0 47.4 77.9 128.5 74.6 67.5 76.2 106.8 62.5 147.2 82.0 51.8 60.7 190.6 161.5 124.4 59.0 206.6 234.3 75.4 149.3 176.8 107.7 100.7 98.3 148.8 147.8 102.9 98.1 225.4 76.4 70.9 165.7 64.0 52.5 205.3 204.5 134.6 67.4 62.4 67.5 39.7 108.7 98.3 102.2 99.4 92.3 70.3 59.0 56.8 47.8 175.9 207.8 146.3 109.5 91.8 72.4 478.2 182.1 567.9 224.5 200.5 269.2 564.4 292.6 292.7 128.4 516.7 366.2 305.0 554.2 207.5 239.3 225.2 334.2 400.8 186.3 187.5 209.9 216.8 186.2 223.0 223.4 192.5 214.4 187.0 188.0 177.0 129.8 76.9 158.9 19.9 206.3 98.1 148.6 227.0 98.4 46.2 137.5 212.3 674.1 145.8 148.6 233.6 10.4 453.7 142.2 120.1 1430.2 154.3 433.2 78.1 76.5 140.8 75.0 165.5 52.6 149.8 164.0 165.5 64.2 37.1 116.5 89.1 126.0 112.3 263.0 45.4 53.7 117.6 193.3 140.1 110.2 969.5 202.0 129.9 249.1 23.4 502.4 167.9 163.7 14.6 26.0 141.3 96.3 308.4 299.4 171.8 235.9 1315.1 160.4 45.8 223.5 97.4 158.1 294.5 242.1 92.6 93.1 475.2 153.6 154.2 139.8 177.7 ITGB1BP2 CHORDC3 ENSG00000147166 "Integrin subunit beta 1 binding protein 2" Q9UKP3 X 71301750-71305371 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 89.4;skeletal muscle: 46.1;tongue: 52.9" "Cell type enriched" "Detected in some" 9 "Cardiomyocytes: 80.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 9.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA040721 Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "HPA040721: AB_10805827" "unprognostic (1.87e-1)" "unprognostic (2.65e-2)" "unprognostic (6.91e-5)" "unprognostic (1.95e-2)" "unprognostic (7.92e-2)" "unprognostic (1.54e-1)" "unprognostic (3.81e-2)" "unprognostic (9.02e-2)" "unprognostic (4.69e-2)" "unprognostic (2.15e-2)" "unprognostic (4.85e-2)" "unprognostic (3.17e-1)" "unprognostic (3.08e-11)" "unprognostic (4.38e-2)" "unprognostic (3.63e-2)" "unprognostic (2.99e-1)" "unprognostic (2.64e-1)" 0.7 0.6 0.5 1.5 0.6 1.5 0.5 1.0 0.9 2.4 0.5 6.5 1.0 16.6 3.0 4.1 3.3 2.5 89.4 0.6 0.6 0.8 1.4 1.0 0.9 0.6 0.6 1.6 0.5 0.0 0.5 0.3 0.6 6.0 1.8 1.8 1.3 10.3 46.1 0.6 2.1 16.3 0.5 1.1 2.0 1.3 0.6 1.0 0.7 52.9 0.6 5.5 1.5 0.7 0.5 1.4 2.1 1.8 0.1 0.1 0.4 0.7 1.0 0.5 0.5 0.9 1.1 2.1 0.2 1.1 0.5 0.9 1.9 0.6 1.1 0.7 0.9 1.3 1.5 0.4 0.2 0.4 9.3 1.1 0.7 0.2 0.3 0.4 0.8 2.2 1.0 0.5 1.1 0.4 0.8 2.3 3.1 1.4 0.9 1.4 1.6 0.8 1.0 1.3 1.0 0.3 0.5 0.1 0.6 1.4 0.5 0.3 0.0 0.9 1.8 0.1 0.4 1.8 2.8 3.1 0.2 1.6 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 1.0 0.9 0.6 0.6 0.6 0.6 0.6 0.5 0.6 0.7 0.2 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.0 1.7 0.3 0.3 80.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.6 0.1 0.2 0.2 0.8 0.0 0.4 0.2 0.0 0.1 2.3 0.0 0.2 0.0 0.4 1.1 0.8 0.2 0.0 0.3 0.1 0.0 0.0 0.3 0.0 0.3 0.2 0.0 0.0 0.3 0.1 1.0 0.0 0.5 0.2 0.1 8.6 0.0 0.3 0.1 0.5 0.3 1.1 0.0 0.6 2.5 0.5 0.4 0.0 0.3 0.0 0.1 0.6 0.3 0.1 IVNS1ABP "ARA3, HSPC068, KIAA0850, KLHL39, ND1, NS-1, NS1-BP" ENSG00000116679 "Influenza virus NS1A binding protein" Q9Y6Y0 1 185296388-185317273 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 452.5" "Cell type enhanced" "Detected in all" "Granulosa cells: 309.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 250.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003405 Approved Supported Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA003405: AB_1079141" "unprognostic (4.11e-3)" "unprognostic (9.69e-2)" "unprognostic (4.29e-2)" "unprognostic (1.77e-1)" "unprognostic (2.03e-2)" "unprognostic (4.42e-2)" "unprognostic (4.31e-3)" "unprognostic (4.18e-1)" "unprognostic (7.04e-2)" "unprognostic (5.13e-2)" "unprognostic (4.28e-1)" "unprognostic (5.42e-3)" "unprognostic (1.85e-3)" "unprognostic (3.73e-2)" "unprognostic (1.28e-1)" "unprognostic (4.07e-2)" "unprognostic (4.13e-2)" 43.9 17.8 16.7 46.6 26.5 452.5 50.5 21.1 20.8 24.9 26.9 40.2 38.4 22.4 18.1 27.0 19.6 36.4 28.9 15.2 19.7 94.1 23.0 27.7 26.4 20.9 18.3 28.4 25.5 32.4 17.3 26.0 22.3 22.2 51.1 15.0 55.2 26.4 23.1 33.5 34.8 16.9 18.3 27.3 42.2 15.9 20.0 24.9 34.3 21.6 24.1 37.7 29.8 35.0 24.6 22.1 79.2 31.6 27.1 9.0 68.4 46.6 15.3 30.1 27.5 26.2 39.7 36.8 36.8 24.0 13.4 32.9 29.0 31.8 32.1 24.9 21.6 36.8 39.1 22.6 10.9 26.2 13.9 6.7 35.7 23.1 73.2 67.6 39.6 38.6 23.6 21.2 54.6 18.0 44.6 18.1 48.7 61.8 5.6 24.7 20.2 21.0 250.7 31.4 52.5 44.5 40.6 35.4 31.4 103.4 16.2 13.3 27.2 41.9 24.5 10.4 34.9 28.0 23.8 22.8 32.1 26.0 19.4 7.9 10.9 10.5 10.5 7.1 9.6 6.1 8.0 7.7 12.6 3.7 8.5 8.3 33.0 10.4 10.3 3.4 8.9 12.1 16.7 26.5 21.1 20.8 15.2 19.7 20.9 18.3 22.3 18.3 20.0 35.0 159.1 44.8 59.0 13.7 61.3 188.9 90.4 40.9 163.4 14.5 74.0 51.3 56.0 22.8 57.4 128.8 52.1 17.3 102.0 288.3 164.4 41.6 34.4 93.2 36.7 85.8 60.4 52.8 18.2 41.5 67.5 50.3 90.7 159.7 41.1 309.2 26.4 23.3 34.8 21.9 26.2 109.6 36.7 107.2 242.3 34.9 5.9 141.5 101.4 33.7 41.3 11.3 63.8 37.7 72.9 24.0 56.4 2.6 62.7 60.9 103.2 86.3 45.8 32.7 6.6 51.4 52.6 33.2 19.8 108.9 181.6 18.3 120.0 54.2 102.7 91.7 JMJD7 ENSG00000243789 "Jumonji domain containing 7" P0C870 15 41828092-41837581 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Monooxygenase, Oxidoreductase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 5.2;Basal squamous epithelial cells: 1.8;Gastric mucus-secreting cells: 2.0;Squamous epithelial cells: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 31.2;RT4: 43.5" "Low region specificity" "Detected in all" HPA005726 Approved Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Cytosol "HPA005726: AB_1852017" "unprognostic (2.92e-1)" "unprognostic (7.99e-2)" "unprognostic (1.47e-2)" "unprognostic (2.30e-2)" "unprognostic (9.46e-2)" "unprognostic (1.03e-1)" "unprognostic (1.59e-1)" "unprognostic (1.78e-2)" "unprognostic (2.11e-2)" "unprognostic (1.77e-1)" "unprognostic (2.42e-1)" "unprognostic (8.74e-3)" "unprognostic (3.13e-1)" "unprognostic (7.25e-2)" "unprognostic (1.06e-1)" "unprognostic (3.30e-1)" "unprognostic (1.45e-2)" 6.7 8.4 6.3 4.2 6.2 8.2 9.0 19.9 9.5 13.6 8.0 7.3 4.8 6.5 3.1 35.4 8.6 6.5 11.2 5.8 6.3 10.1 10.3 10.8 7.3 5.8 5.2 11.6 15.9 9.0 9.8 3.0 7.0 14.5 3.0 1.9 21.9 6.8 7.7 33.3 8.0 2.9 5.1 7.9 11.5 6.7 5.9 5.6 15.6 6.6 6.6 11.4 21.0 7.0 7.9 7.5 9.3 2.6 2.5 1.7 5.8 3.1 6.6 5.1 4.1 10.5 5.9 1.0 6.4 2.0 5.3 19.6 4.3 15.6 1.6 7.7 4.6 10.5 10.4 6.5 4.1 5.1 11.0 1.1 13.6 3.4 7.2 4.7 5.8 9.9 7.0 6.2 3.7 10.8 6.6 4.9 4.0 31.2 4.8 2.9 6.3 7.6 11.5 43.5 9.9 3.5 2.6 13.5 4.3 2.7 26.2 5.4 5.4 3.7 8.3 8.0 6.1 10.2 3.7 3.2 4.9 12.4 5.7 6.1 14.8 10.8 14.1 15.8 14.8 7.2 15.7 18.6 10.6 11.1 19.7 15.6 3.9 13.0 15.8 6.7 16.7 12.6 6.3 6.2 19.9 9.5 5.8 6.3 5.8 5.2 7.0 5.1 5.9 7.0 0.1 3.2 5.2 0.0 0.4 0.0 0.0 0.0 1.8 0.0 0.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.1 0.0 0.8 0.0 0.2 0.0 0.2 2.0 0.1 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.1 3.4 0.1 0.0 0.6 0.0 0.0 0.0 JMJD7-PLA2G4B ENSG00000168970 "JMJD7-PLA2G4B readthrough" 15 41828095-41848155 "Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Alveolar cells type 2: 4.8;Club cells: 2.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "RT4: 2.6" HPA005726 Approved Approved Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 15: RT4 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Cytosol "HPA005726: AB_1852017" "unprognostic (9.87e-3)" "unprognostic (5.65e-2)" "unprognostic (1.27e-2)" "unprognostic (6.86e-3)" "unprognostic (1.04e-1)" "unprognostic (1.84e-3)" "unprognostic (1.47e-1)" "unprognostic (7.21e-3)" "unprognostic (4.52e-2)" "unprognostic (4.92e-2)" "unprognostic (1.53e-2)" "unprognostic (1.02e-3)" "unprognostic (1.02e-3)" "unprognostic (3.98e-1)" "unprognostic (1.33e-1)" "unprognostic (2.15e-1)" "unprognostic (4.75e-3)" 1.1 0.3 0.1 0.8 0.0 1.0 0.9 0.3 0.4 1.4 0.5 0.9 0.2 1.1 0.4 1.9 1.1 0.4 0.6 0.1 0.1 0.4 0.3 0.9 0.2 0.1 0.1 1.2 0.5 0.9 0.4 0.1 0.3 0.7 0.2 0.2 1.5 0.4 0.8 2.8 0.8 0.6 0.1 0.6 0.8 0.3 0.3 0.4 0.8 0.5 0.3 1.0 1.4 0.2 0.2 0.0 0.6 2.0 0.5 1.3 0.7 0.4 1.1 0.5 0.8 0.8 0.0 0.2 0.8 0.5 0.0 1.8 0.2 1.2 0.1 0.0 0.2 0.3 0.4 0.2 1.9 0.0 0.9 0.7 0.9 0.2 0.4 0.0 0.2 0.7 0.0 0.3 0.1 0.3 0.2 0.0 0.0 0.4 0.1 0.3 0.0 0.8 0.5 2.6 0.6 0.8 1.8 0.0 0.2 0.0 0.4 2.1 0.3 0.3 0.2 2.0 0.7 0.5 0.2 0.0 1.0 0.2 0.2 0.0 0.3 0.0 1.1 0.4 0.5 0.2 0.1 0.1 0.3 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.1 0.0 0.3 0.4 0.1 0.1 0.1 0.1 0.3 0.1 0.3 0.2 0.2 9.6 4.8 0.0 0.9 0.1 0.2 0.1 2.2 0.6 0.4 0.1 0.6 1.5 2.7 0.0 0.0 0.2 0.1 1.1 0.0 0.6 0.0 0.1 0.3 0.4 2.4 0.0 0.0 0.5 0.1 0.2 1.5 0.4 1.3 0.1 0.0 0.2 0.1 0.0 0.1 0.9 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.2 0.1 1.0 0.0 0.1 1.1 0.5 0.0 2.3 0.1 1.2 0.0 0.9 0.6 0.0 0.1 0.2 0.0 0.1 2.0 1.0 0.1 1.0 0.1 1.2 0.1 JPH4 "JPHL1, KIAA1831" ENSG00000092051 "Junctophilin 4" Q96JJ6 14 23568035-23578790 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 126.2;pituitary gland: 66.5" "Group enriched" "Detected in some" 13 "Bipolar cells: 191.4;Horizontal cells: 410.5" "Cancer enhanced" "Detected in some" "glioma: 6.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.8;myeloid DC: 3.2" "Group enriched" "Detected in many" 8 "dendritic cells: 3.2;monocytes: 2.8" "Group enriched" "Detected in some" 6 "SCLC-21H: 14.2;SH-SY5Y: 35.4;U-2 OS: 26.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045022 Approved Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Cytosol "HPA045022: " "unprognostic (3.30e-2)" "unprognostic (1.91e-3)" "unprognostic (5.05e-3)" "unprognostic (7.41e-2)" "unprognostic (2.04e-1)" "unprognostic (1.84e-1)" "unprognostic (3.77e-3)" "unprognostic (5.98e-4)" "unprognostic (1.58e-1)" "unprognostic (1.16e-1)" "unprognostic (3.89e-3)" "unprognostic (1.15e-2)" "unprognostic (3.15e-2)" "unprognostic (2.10e-2)" "unprognostic (1.91e-1)" "unprognostic (2.13e-2)" "unprognostic (4.96e-3)" 1.5 11.7 83.7 1.0 88.5 0.2 1.0 25.2 126.2 8.4 0.0 1.7 0.8 24.3 5.2 0.4 13.7 0.5 0.3 115.4 29.3 3.0 0.3 2.5 1.0 14.5 11.0 13.6 0.5 1.8 66.5 0.5 11.2 12.3 0.6 12.5 0.3 36.8 0.2 0.9 1.3 12.9 7.2 2.6 0.9 1.4 31.7 0.3 0.4 0.5 0.6 1.6 6.6 57.2 0.0 0.0 0.7 3.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.0 4.4 0.0 0.2 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.7 14.2 35.4 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 26.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.3 2.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 83.7 88.5 25.2 126.2 115.4 29.3 14.5 11.0 11.2 7.2 31.7 57.2 0.3 0.0 0.6 0.7 0.0 0.0 0.2 0.0 0.0 191.4 0.2 0.1 1.3 0.0 0.0 0.0 4.2 0.0 0.0 0.1 0.0 0.0 0.3 0.3 5.7 1.7 1.8 0.0 22.1 0.0 0.0 1.4 0.0 0.1 5.1 1.2 1.8 0.0 2.0 410.5 18.3 0.2 0.0 1.3 9.3 0.2 10.8 0.9 0.0 0.0 0.1 1.6 0.0 15.6 0.4 0.0 0.0 14.7 0.0 0.0 0.0 0.0 0.0 7.7 13.1 0.1 2.3 0.5 3.4 0.0 0.0 0.0 0.0 0.1 0.0 0.8 KANSL1L "C2orf67, FLJ23861, FLJ32349, KIAA1267L, MSL1v2" ENSG00000144445 "KAT8 regulatory NSL complex subunit 1 like" A0AUZ9 2 210021421-210171409 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "parathyroid gland: 198.9" "Cell type enhanced" "Detected in many" "Astrocytes: 113.6;Inhibitory neurons: 117.9;Microglial cells: 103.0;Oligodendrocyte precursor cells: 190.5;Oligodendrocytes: 158.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043102, HPA046790" Uncertain Approved Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "HPA043102: AB_2678316, HPA046790: AB_2679808" "unprognostic (3.85e-2)" "unprognostic (2.37e-1)" "unprognostic (1.04e-1)" "unprognostic (7.55e-3)" "unprognostic (1.45e-2)" "unprognostic (2.55e-3)" "unprognostic (5.52e-2)" "unprognostic (1.46e-1)" "unprognostic (5.99e-3)" "unprognostic (4.65e-2)" "unprognostic (5.89e-3)" "unprognostic (5.75e-2)" "unprognostic (5.95e-3)" "unprognostic (7.44e-2)" "unprognostic (4.60e-2)" "unprognostic (3.21e-2)" "unprognostic (1.30e-3)" 11.6 8.3 10.7 6.2 13.5 5.5 10.3 14.3 9.2 14.4 8.9 9.9 6.5 18.7 17.4 6.9 13.2 15.7 9.7 9.7 11.7 22.7 9.4 11.9 6.7 11.3 12.6 28.5 15.2 198.9 10.0 8.3 12.0 16.9 6.8 12.5 10.0 17.0 12.1 13.3 6.7 13.3 10.6 6.3 12.4 25.3 10.8 26.7 19.7 18.4 5.2 13.6 11.3 17.7 2.7 1.4 14.5 6.1 11.7 8.7 4.0 4.1 5.4 2.7 7.4 2.7 10.9 7.9 5.5 2.8 6.5 3.8 3.4 1.5 4.3 3.4 2.7 6.3 6.1 4.6 7.3 7.4 4.3 5.5 6.5 2.7 1.9 11.5 6.1 7.2 4.5 7.1 4.1 2.7 8.5 19.7 8.4 4.8 1.9 6.1 3.9 6.1 16.0 4.0 9.0 8.5 3.7 2.3 2.9 14.4 2.5 16.1 4.9 5.3 4.3 1.9 3.1 4.9 2.2 7.7 7.0 3.5 7.1 0.2 0.3 0.5 0.2 0.4 0.2 0.1 0.2 0.2 0.4 0.3 0.3 0.3 0.4 0.6 0.1 0.3 0.1 0.1 10.7 13.5 14.3 9.2 9.7 11.7 11.3 12.6 12.0 10.6 10.8 17.7 12.8 28.9 20.1 113.6 4.6 7.4 6.7 3.9 11.4 8.6 5.4 6.7 9.2 20.0 6.6 31.3 14.6 1.7 1.5 2.3 3.9 13.2 30.3 22.3 17.0 8.8 6.0 4.6 79.0 5.5 0.9 14.2 9.2 14.7 10.8 23.6 6.4 7.4 2.7 5.0 117.9 3.2 8.2 2.8 6.7 22.2 14.6 8.5 7.2 103.0 5.5 9.6 4.1 190.5 158.9 6.7 4.7 30.1 3.0 7.0 2.0 15.8 36.0 8.7 13.1 31.1 15.6 44.9 7.8 5.5 11.1 1.9 2.7 6.6 2.8 4.1 KCNE5 KCNE1L ENSG00000176076 "Potassium voltage-gated channel subfamily E regulatory subunit 5" Q9UJ90 X 109623700-109625172 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Alport syndrome, Deafness, Elliptocytosis, Hereditary hemolytic anemia, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.8;skeletal muscle: 4.0;tongue: 4.9" "Cell type enhanced" "Detected in some" "Astrocytes: 4.6;Erythroid cells: 3.8;monocytes: 9.4;Muller glia cells: 5.3;Peritubular cells: 3.8" "Group enriched" "Detected in some" 8 "glioma: 7.9;testis cancer: 2.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HMC-1: 1.5;hTEC/SVTERT24-B: 2.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042316 Uncertain Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "HPA042316: AB_10795397" "unprognostic (5.33e-2)" "unprognostic (2.28e-2)" "unprognostic (1.62e-1)" "unprognostic (1.15e-1)" "unprognostic (1.59e-2)" "unprognostic (1.01e-1)" "unprognostic (2.14e-3)" "unprognostic (3.27e-2)" "unprognostic (9.46e-2)" "unprognostic (1.05e-1)" "unprognostic (4.62e-3)" "unprognostic (7.83e-2)" "unprognostic (5.64e-6)" "unprognostic (5.10e-2)" "unprognostic (9.06e-2)" "unprognostic (1.36e-1)" "unprognostic (5.37e-3)" 1.1 0.8 3.2 0.1 5.4 1.6 0.5 9.4 2.7 0.2 0.7 0.1 0.0 0.0 0.1 0.1 0.0 0.4 0.7 2.7 6.6 0.7 0.2 0.4 0.0 6.3 9.8 0.5 0.1 0.0 0.3 0.2 6.9 0.3 0.0 0.2 0.2 0.3 4.0 0.1 0.1 0.1 4.0 0.9 0.1 0.3 7.8 2.3 0.1 4.9 0.0 0.3 0.2 4.6 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.1 0.2 0.2 0.0 0.1 0.1 0.0 0.1 0.3 0.3 0.0 0.8 0.3 0.0 0.1 1.0 1.1 0.7 0.0 0.0 1.5 0.2 0.5 2.0 0.5 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.5 0.0 0.4 0.5 0.0 0.9 0.4 0.7 0.3 0.3 0.9 0.2 0.2 0.1 0.4 0.4 0.1 0.0 0.3 0.0 0.3 0.8 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 3.2 5.4 9.4 2.7 2.7 6.6 6.3 9.8 6.9 4.0 7.8 4.6 0.1 0.0 1.1 4.6 0.1 0.0 0.0 0.0 1.2 0.0 0.3 1.1 0.6 0.0 0.0 0.0 0.0 0.4 2.2 0.0 0.0 0.3 0.0 0.5 0.1 0.2 0.0 3.8 0.1 0.4 1.2 1.4 0.0 0.5 1.3 0.7 1.1 0.0 0.6 0.0 0.1 0.0 0.0 2.0 0.0 0.0 1.2 2.1 0.0 1.0 9.4 5.3 0.0 0.0 0.0 0.3 0.0 3.8 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.2 0.4 0.0 0.0 0.1 0.0 0.8 0.2 0.1 0.0 0.1 KCNMB4 ENSG00000135643 "Potassium calcium-activated channel subfamily M regulatory beta subunit 4" Q86W47 12 70366290-70434292 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.2;choroid plexus: 18.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 95.7;Hepatic stellate cells: 37.1;Inhibitory neurons: 45.0;Oligodendrocytes: 86.9" "Cancer enhanced" "Detected in many" "glioma: 10.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 7.7;RH-30: 8.2;RT4: 9.3;SuSa: 7.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072287 Enhanced Approved Approved Cytosol NA NA "Cluster 70: Brain - Nervous system development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA072287: AB_2686507" "unprognostic (3.90e-1)" "unprognostic (1.72e-2)" "unprognostic (2.69e-2)" "unprognostic (2.62e-2)" "unprognostic (6.98e-2)" "unprognostic (1.13e-3)" "unprognostic (1.85e-1)" "unprognostic (2.48e-2)" "unprognostic (3.50e-1)" "unprognostic (2.95e-2)" "unprognostic (3.75e-1)" "unprognostic (2.47e-2)" "unprognostic (2.19e-2)" "unprognostic (1.96e-1)" "unprognostic (1.78e-1)" "unprognostic (4.62e-2)" "unprognostic (1.05e-2)" 2.3 14.9 35.3 1.1 39.5 0.2 2.0 29.7 43.5 3.1 18.9 8.6 1.0 1.8 1.1 1.0 1.7 1.4 4.7 36.4 29.7 3.7 0.5 6.1 1.3 38.5 32.2 2.6 0.5 0.2 1.9 2.5 32.1 3.2 1.2 1.9 1.7 2.1 2.4 2.6 3.0 1.2 28.9 1.2 2.1 2.1 38.4 1.3 2.1 1.5 1.0 2.5 2.6 54.2 0.0 0.3 4.9 2.7 0.3 0.2 0.5 0.6 0.9 0.2 0.7 0.2 1.8 2.4 0.3 0.0 1.0 0.0 5.3 0.8 0.2 1.1 3.1 1.3 1.1 2.9 0.0 0.1 0.1 1.4 0.1 0.0 0.0 0.5 0.2 3.5 0.0 0.0 0.9 0.7 1.8 0.4 7.7 0.1 5.6 2.6 8.2 0.2 0.2 9.3 2.4 2.9 0.7 0.9 0.0 7.3 2.7 0.1 0.1 0.3 1.3 0.1 0.3 1.7 0.0 2.5 0.4 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.3 0.4 0.6 0.0 0.0 0.0 0.0 0.1 0.1 35.3 39.5 29.7 43.5 36.4 29.7 38.5 32.2 32.1 28.9 38.4 54.2 8.5 0.0 0.6 2.6 1.1 3.2 0.2 0.4 0.6 23.1 2.8 1.9 4.3 0.0 0.2 23.9 0.0 0.2 2.1 0.1 0.0 0.1 0.9 4.7 1.1 8.7 0.0 3.2 95.7 0.0 0.4 9.6 0.0 3.4 0.0 7.2 37.1 0.7 1.2 0.0 45.0 0.4 0.0 10.8 2.6 2.2 6.5 2.9 1.8 20.6 0.7 1.5 0.0 13.6 86.9 0.0 0.0 18.0 0.2 0.8 0.0 9.7 0.0 3.0 0.0 12.8 5.1 2.2 7.8 0.2 5.5 0.3 1.4 14.0 0.5 0.0 KCTD21 KCASH2 ENSG00000188997 "Potassium channel tetramerization domain containing 21" Q4G0X4 11 78171249-78188626 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041964 Uncertain Approved Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA041964: AB_10795647" "unprognostic (1.17e-1)" "unprognostic (5.45e-2)" "unprognostic (3.74e-3)" "unprognostic (6.40e-3)" "unprognostic (8.06e-2)" "unprognostic (2.48e-2)" "unprognostic (1.52e-1)" "unprognostic (6.82e-2)" "unprognostic (8.85e-2)" "unprognostic (1.37e-3)" "unprognostic (2.49e-1)" "unprognostic (1.31e-1)" "unprognostic (4.35e-2)" "unprognostic (1.77e-1)" "unprognostic (4.70e-1)" "prognostic favorable (9.57e-5)" "unprognostic (3.43e-2)" 7.3 13.4 14.4 6.2 13.6 3.5 4.4 13.1 14.3 5.8 8.7 6.5 5.0 5.0 9.2 9.6 6.2 7.9 6.3 13.7 14.3 5.5 15.9 6.7 5.4 14.7 16.3 13.7 3.5 5.7 5.9 7.7 15.0 4.2 4.8 4.3 5.8 5.2 8.5 4.9 4.5 7.1 12.4 4.6 4.5 4.0 14.6 5.9 11.2 7.0 6.2 7.1 5.9 14.7 5.2 11.8 6.7 5.0 23.8 16.9 4.1 10.1 9.6 7.1 7.1 11.1 7.8 5.0 9.9 11.4 9.5 10.1 6.5 8.4 7.3 6.9 3.9 3.8 15.4 9.8 13.2 2.4 4.7 16.4 15.4 15.5 8.8 14.8 11.0 6.1 8.1 4.5 9.7 7.3 3.8 7.3 3.0 19.0 8.9 5.0 5.1 3.1 8.3 9.3 4.6 7.1 6.4 4.6 4.9 12.1 10.6 2.6 12.9 11.3 11.0 30.0 3.9 8.6 9.2 4.8 5.9 3.9 6.4 2.0 5.4 7.5 0.9 6.0 1.4 0.6 1.4 1.7 3.7 1.4 1.3 1.0 8.3 1.4 5.1 0.8 1.1 2.2 14.4 13.6 13.1 14.3 13.7 14.3 14.7 16.3 15.0 12.4 14.6 14.7 1.9 0.0 2.7 4.6 0.7 1.8 1.2 1.5 0.6 1.7 2.4 2.2 3.5 5.7 2.0 0.0 0.0 1.2 0.6 2.8 1.9 1.5 0.3 1.4 2.5 2.3 0.0 0.0 4.1 2.2 1.1 2.8 1.1 1.9 5.7 7.0 3.6 7.4 2.3 6.7 3.4 1.3 0.0 3.1 1.1 0.5 4.4 1.3 1.8 4.7 2.8 1.0 0.0 4.0 4.2 2.5 1.7 9.1 1.0 1.9 2.3 2.7 1.1 0.9 0.0 1.2 2.9 1.5 2.7 3.6 1.4 1.9 1.8 3.8 1.7 2.1 KCTD3 NY-REN-45 ENSG00000136636 "Potassium channel tetramerization domain containing 3" Q9Y597 1 215567304-215621807 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 106.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "T-47d: 227.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015142 Approved Approved Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 30: Mammary glandular cells - Lactation" Cytosol "HPA015142: AB_1852174" "unprognostic (1.62e-1)" "unprognostic (2.00e-2)" "unprognostic (5.46e-3)" "unprognostic (3.91e-2)" "unprognostic (3.67e-2)" "unprognostic (6.00e-2)" "unprognostic (3.39e-1)" "unprognostic (1.20e-2)" "unprognostic (5.60e-3)" "unprognostic (9.27e-2)" "prognostic unfavorable (4.71e-4)" "unprognostic (1.49e-1)" "prognostic unfavorable (8.94e-6)" "unprognostic (2.30e-2)" "unprognostic (2.55e-1)" "unprognostic (4.27e-1)" "unprognostic (3.31e-3)" 35.1 77.2 19.6 11.8 26.9 15.9 67.2 34.8 21.8 23.8 19.3 35.1 45.5 23.6 27.4 38.7 19.3 27.7 13.0 19.4 23.2 27.7 71.8 17.0 8.6 29.1 25.4 23.4 32.8 36.7 12.0 29.7 29.9 38.5 28.4 39.8 27.7 29.6 15.2 18.8 49.5 28.9 25.1 11.6 26.7 20.1 25.5 11.3 27.6 23.8 10.9 23.9 30.7 33.8 52.8 37.2 41.6 24.1 34.3 57.5 57.1 42.8 40.0 37.1 38.5 33.0 85.6 14.6 23.4 45.0 11.1 50.3 44.1 43.4 42.5 8.2 45.8 26.3 71.0 46.3 28.3 26.9 5.1 53.5 30.0 47.0 35.5 46.7 34.6 19.8 51.8 13.9 41.1 45.6 11.7 13.8 69.9 76.2 47.0 17.7 58.8 56.9 42.8 35.2 48.7 54.0 65.9 95.0 36.6 52.1 227.5 34.3 31.1 36.8 36.4 46.1 49.4 12.5 18.2 5.3 29.0 14.1 28.5 0.5 0.4 0.2 0.2 0.2 0.1 0.4 0.2 0.2 0.4 0.5 0.2 0.2 0.7 0.5 0.2 0.6 0.1 0.2 19.6 26.9 34.8 21.8 19.4 23.2 29.1 25.4 29.9 25.1 25.5 33.8 26.5 9.6 11.6 41.4 2.4 18.0 25.2 9.4 19.4 31.7 60.0 31.9 13.3 40.0 17.6 11.0 18.8 27.2 4.6 15.5 23.5 26.6 1.3 14.0 29.8 20.6 39.6 19.3 53.5 20.7 15.7 30.3 21.4 19.6 5.1 30.7 16.1 60.5 8.0 18.5 62.9 40.6 14.2 9.3 8.4 3.2 27.7 7.9 16.0 33.7 5.5 24.0 0.0 53.3 106.7 16.5 19.1 22.6 4.6 21.9 50.1 28.3 14.4 24.2 26.3 41.8 20.4 6.3 14.6 45.2 17.6 17.5 2.5 32.0 33.0 38.3 KIAA0232 ENSG00000170871 KIAA0232 Q92628 4 6781375-6884170 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 10.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036891, HPA036892, HPA061498" Approved Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 6: Erythroid cells - Oxygen transport" Cytosol "HPA036891: AB_10672272, HPA036892: AB_2675366, HPA061498: AB_2684541" "unprognostic (6.88e-3)" "unprognostic (2.74e-1)" "unprognostic (8.98e-2)" "unprognostic (4.87e-2)" "unprognostic (2.43e-1)" "unprognostic (4.13e-2)" "unprognostic (1.85e-1)" "unprognostic (2.19e-1)" "unprognostic (1.85e-1)" "unprognostic (3.16e-1)" "unprognostic (1.32e-2)" "unprognostic (2.78e-1)" "prognostic favorable (3.91e-10)" "unprognostic (1.21e-1)" "unprognostic (8.57e-2)" "unprognostic (2.04e-1)" "unprognostic (3.18e-2)" 13.0 12.0 18.6 8.5 19.9 16.2 13.3 20.2 20.9 12.0 17.8 14.0 8.5 15.4 12.6 20.6 15.3 12.4 33.2 18.0 22.3 18.8 15.0 12.0 7.5 18.2 22.5 13.1 10.6 23.9 10.3 10.4 19.8 14.7 12.3 24.7 8.9 14.6 32.5 7.6 11.5 13.1 20.1 12.9 10.9 12.0 23.4 11.7 15.1 51.1 8.6 10.4 9.8 21.0 13.7 13.0 26.7 16.7 18.8 20.2 14.0 17.4 18.1 12.0 10.1 8.2 11.3 9.0 5.8 19.7 18.5 7.0 13.7 7.7 15.5 5.1 5.6 26.7 11.1 11.0 9.9 11.6 33.6 13.6 17.7 13.4 7.4 15.4 12.6 8.9 20.3 7.6 15.4 6.7 22.3 11.7 14.1 10.2 14.3 15.7 27.3 4.2 20.3 12.8 20.2 13.1 12.9 11.4 12.1 18.3 14.5 21.1 16.0 11.0 12.8 9.8 15.2 13.1 14.1 7.0 13.5 12.2 30.3 2.0 2.0 5.7 2.1 1.4 2.9 1.3 1.6 2.5 1.3 1.3 1.5 1.6 10.6 1.8 2.1 2.0 1.6 0.9 18.6 19.9 20.2 20.9 18.0 22.3 18.2 22.5 19.8 20.1 23.4 21.0 27.6 32.1 39.2 62.3 19.1 12.7 27.4 12.9 24.5 77.2 29.0 20.6 132.1 10.0 29.0 12.9 37.5 14.7 23.6 47.9 41.1 23.4 45.0 74.4 28.0 20.6 25.1 49.9 123.8 11.7 7.7 27.7 44.9 38.7 12.6 16.3 15.0 42.9 11.2 99.3 120.7 20.9 30.5 23.9 11.8 64.2 24.8 28.4 7.2 73.1 34.8 49.7 27.8 90.0 138.0 21.8 24.8 33.1 24.2 28.0 29.6 24.6 58.0 44.6 26.3 39.4 31.6 31.6 22.4 19.2 11.1 22.4 27.4 27.0 17.5 35.7 KLHDC1 MST025 ENSG00000197776 "Kelch domain containing 1" Q8N7A1 14 49693105-49753150 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 46.4;Excitatory neurons: 41.7;Inhibitory neurons: 51.1;Microglial cells: 49.6;Oligodendrocyte precursor cells: 45.2;Oligodendrocytes: 90.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 5.7;ASC TERT1: 5.3;HSkMC: 4.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020461 Approved Supported Cytosol No No "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA020461: AB_1852556" "unprognostic (2.97e-2)" "unprognostic (6.30e-2)" "unprognostic (8.49e-3)" "unprognostic (1.26e-2)" "unprognostic (5.46e-2)" "unprognostic (1.32e-2)" "unprognostic (1.32e-1)" "unprognostic (1.95e-2)" "unprognostic (1.01e-1)" "unprognostic (2.53e-1)" "prognostic favorable (1.94e-4)" "unprognostic (3.42e-1)" "unprognostic (5.61e-2)" "unprognostic (3.14e-2)" "unprognostic (1.13e-1)" "unprognostic (8.45e-2)" "unprognostic (2.24e-1)" 5.2 4.2 3.3 2.3 5.1 1.4 4.8 4.5 6.0 6.2 1.5 5.5 1.9 6.0 5.7 2.2 5.8 3.1 4.6 2.8 5.4 3.1 3.5 3.1 3.6 5.0 4.2 9.3 3.8 4.1 6.2 2.6 4.3 4.6 2.3 6.0 3.3 4.3 7.2 5.1 3.8 3.5 3.1 3.8 3.9 4.8 4.0 1.9 5.6 4.7 2.6 4.4 4.8 7.4 0.7 0.3 0.6 0.3 5.7 5.3 0.0 1.5 2.1 0.5 0.3 0.0 1.8 0.3 0.3 0.6 0.5 0.5 0.1 0.0 0.4 1.5 0.5 0.2 0.1 0.0 2.9 0.1 0.7 4.5 0.2 0.2 0.2 2.9 1.2 1.0 0.3 0.0 2.2 0.2 0.4 0.8 0.0 0.2 0.2 0.4 0.5 0.0 1.1 0.2 0.2 1.5 0.2 0.0 0.6 0.7 0.6 1.2 1.7 1.3 1.4 0.5 0.1 0.5 0.0 0.4 1.2 0.2 0.7 0.5 0.4 1.0 0.7 0.8 1.4 1.2 1.0 0.9 0.4 0.8 1.7 1.4 0.0 0.6 0.4 1.4 0.3 0.7 3.3 5.1 4.5 6.0 2.8 5.4 5.0 4.2 4.3 3.1 4.0 7.4 7.6 22.4 6.5 46.4 6.1 3.6 3.4 1.5 4.0 10.4 3.3 2.3 10.1 5.7 5.7 0.0 4.2 1.5 2.7 1.7 9.8 0.8 2.1 3.5 5.4 5.7 1.8 5.2 41.7 0.8 0.8 7.3 2.6 1.9 1.3 4.5 4.6 3.2 2.6 13.5 51.1 2.4 2.0 2.2 3.3 3.3 18.0 2.9 5.4 49.6 2.2 15.0 4.1 45.2 90.5 0.4 2.7 10.1 2.9 1.6 4.2 2.5 3.1 15.8 0.0 9.5 6.1 17.9 7.6 1.3 3.3 0.3 3.7 4.2 1.2 1.8 KLHDC8B MGC35097 ENSG00000185909 "Kelch domain containing 8B" Q8IXV7 3 49171598-49176486 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 128.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 60.7;Sertoli cells: 98.6;Theca cells: 55.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 28.8" "Group enriched" "Detected in many" 10 "granulocytes: 28.8;monocytes: 8.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008463, HPA014467" Approved Enhanced Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Cytosol "HPA008463: AB_1852563, HPA014467: AB_1852565" "unprognostic (1.66e-2)" "unprognostic (1.42e-1)" "unprognostic (5.31e-2)" "unprognostic (8.50e-3)" "unprognostic (2.66e-1)" "unprognostic (5.03e-3)" "unprognostic (1.71e-3)" "prognostic favorable (1.47e-4)" "unprognostic (6.80e-2)" "unprognostic (1.23e-1)" "unprognostic (1.52e-1)" "unprognostic (4.30e-2)" "unprognostic (1.02e-3)" "unprognostic (4.78e-2)" "unprognostic (5.60e-2)" "unprognostic (1.86e-2)" "unprognostic (1.61e-2)" 29.1 128.7 13.5 5.6 14.0 6.1 24.9 9.4 14.8 20.2 24.8 56.1 7.2 26.2 10.6 31.1 26.5 16.7 70.5 12.4 21.2 16.3 12.6 17.3 9.9 12.4 14.2 70.1 9.4 10.4 10.1 12.3 16.1 16.9 3.6 2.3 14.1 13.5 29.6 28.1 14.0 14.2 11.6 13.2 16.7 15.5 19.1 4.3 26.6 13.4 6.8 29.4 22.5 10.3 2.5 5.5 22.4 11.4 13.5 8.0 6.9 8.4 4.7 8.2 6.6 3.6 7.4 0.0 4.6 14.0 2.3 0.1 5.6 5.1 2.1 4.6 1.5 15.1 15.2 9.6 25.6 0.0 8.5 13.3 23.9 10.6 0.8 18.4 21.2 5.3 23.7 0.2 6.3 0.7 1.6 16.7 7.4 1.3 13.1 2.3 2.1 0.7 6.1 1.3 0.9 25.2 6.7 0.2 17.0 4.7 6.8 7.3 9.3 6.2 17.1 11.2 2.6 2.1 0.7 0.3 4.5 0.0 3.1 0.0 5.4 28.8 1.0 8.0 0.4 0.0 0.5 0.7 0.5 0.1 1.8 1.0 9.7 0.0 8.3 0.8 0.2 2.4 13.5 14.0 9.4 14.8 12.4 21.2 12.4 14.2 16.1 11.6 19.1 10.3 14.1 9.6 10.9 5.9 0.9 7.6 11.5 16.4 10.8 2.2 10.8 9.0 60.7 11.5 14.3 7.3 2.1 10.9 2.4 1.0 17.6 14.3 7.2 6.8 6.9 20.5 6.7 6.5 3.8 5.9 8.5 22.3 2.6 3.3 1.3 7.7 37.1 7.5 41.7 0.0 4.6 3.0 18.3 12.0 2.2 7.7 15.2 10.5 12.4 6.5 2.5 29.4 0.0 3.5 0.7 8.6 1.7 14.3 0.6 8.3 0.7 13.4 4.0 2.7 98.6 28.3 31.1 9.2 8.6 15.5 9.8 49.8 1.5 55.5 1.7 7.9 KLHL13 "BKLHD2, FLJ10262, KIAA1309" ENSG00000003096 "Kelch like family member 13" Q9P2N7 X 117897813-118117340 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 31.4" "Cell type enhanced" "Detected in many" "Distal tubular cells: 29.4;Inhibitory neurons: 29.3;Microglial cells: 30.9;Oligodendrocyte precursor cells: 102.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 7.3;plasmacytoid DC: 4.1" "Group enriched" "Detected in many" 5 "dendritic cells: 4.1;granulocytes: 7.3" "Cell line enhanced" "Detected in many" "HAP1: 33.8;HeLa: 57.3;RH-30: 37.2;RPTEC TERT1: 106.0;SH-SY5Y: 94.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046039, HPA059901" Approved Approved Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "HPA046039: AB_2679514, HPA059901: AB_2684155" "unprognostic (1.11e-1)" "unprognostic (2.20e-1)" "unprognostic (1.03e-1)" "unprognostic (6.09e-2)" "unprognostic (1.07e-2)" "unprognostic (9.54e-2)" "unprognostic (7.22e-2)" "unprognostic (5.52e-2)" "unprognostic (1.41e-1)" "unprognostic (2.54e-1)" "unprognostic (6.91e-2)" "unprognostic (1.52e-1)" "unprognostic (3.09e-3)" "unprognostic (1.24e-2)" "unprognostic (3.90e-2)" "unprognostic (1.53e-1)" "unprognostic (2.31e-1)" 2.7 7.3 4.6 2.6 11.1 0.4 24.6 2.7 4.8 20.5 5.5 5.4 3.1 31.4 7.3 5.9 10.7 5.6 7.8 3.2 5.9 16.0 4.7 1.4 0.6 5.9 10.3 7.4 4.6 3.4 2.2 0.8 6.4 6.2 3.9 4.2 2.2 12.3 3.6 1.1 4.8 29.3 4.0 1.6 3.2 3.6 5.9 5.0 0.8 5.6 1.2 7.5 5.0 3.8 1.1 0.4 6.9 14.5 0.1 0.0 0.2 0.5 0.0 0.4 0.0 9.1 0.1 0.0 16.5 0.0 0.7 16.9 33.8 5.6 0.0 0.0 12.9 0.4 57.3 0.1 0.8 1.1 2.2 1.8 2.3 0.2 0.7 6.9 25.8 0.0 0.0 0.0 0.0 1.4 5.9 1.6 13.4 0.0 9.6 0.0 37.2 0.1 106.0 4.0 0.0 94.3 0.5 1.2 0.9 2.7 20.9 0.2 0.7 2.4 2.9 2.0 8.6 0.4 0.0 0.2 10.2 0.0 4.1 2.4 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.6 0.6 0.0 1.1 0.0 4.1 0.2 0.3 4.6 11.1 2.7 4.8 3.2 5.9 5.9 10.3 6.4 4.0 5.9 3.8 0.7 0.0 0.0 13.7 0.0 0.8 6.8 5.4 12.0 6.2 2.4 19.9 10.5 0.0 4.8 1.8 0.0 0.2 0.1 1.2 29.4 1.1 0.3 8.0 22.7 1.9 1.2 1.3 8.0 3.4 0.1 8.7 0.0 1.3 0.0 10.0 8.6 1.3 0.6 0.0 29.3 2.1 0.0 0.0 1.2 0.9 6.2 1.0 1.8 30.9 0.2 7.2 0.0 102.5 12.3 0.7 3.4 1.9 0.1 2.7 2.9 12.7 22.3 1.2 6.6 18.1 5.3 1.8 10.6 4.8 0.4 0.0 0.6 6.4 4.1 3.6 KLHL28 "BTBD5, FLJ20081" ENSG00000179454 "Kelch like family member 28" Q9NXS3 14 44924324-45042322 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 27.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000988 Approved Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA000988: AB_1845480" "unprognostic (8.09e-2)" "unprognostic (1.02e-1)" "unprognostic (1.15e-1)" "unprognostic (1.37e-1)" "unprognostic (7.84e-3)" "unprognostic (9.20e-2)" "unprognostic (4.36e-3)" "unprognostic (4.92e-2)" "unprognostic (2.66e-1)" "unprognostic (2.14e-1)" "unprognostic (1.23e-1)" "unprognostic (1.53e-1)" "unprognostic (4.68e-2)" "unprognostic (7.55e-2)" "unprognostic (4.34e-1)" "unprognostic (1.75e-2)" "unprognostic (6.53e-2)" 4.6 4.8 2.6 6.5 3.4 27.0 5.7 9.0 3.6 5.2 3.3 5.0 5.1 5.3 5.0 6.5 5.4 5.5 4.1 2.9 3.9 4.6 6.4 5.6 8.7 3.2 2.9 7.8 3.8 4.2 3.0 5.6 3.5 5.5 6.0 8.1 4.3 3.9 4.7 5.1 5.0 5.8 3.3 5.8 5.0 7.3 3.3 9.2 7.6 8.0 7.4 5.6 3.5 6.4 4.5 6.7 8.6 5.6 7.7 6.8 6.5 5.8 6.4 8.4 7.1 3.0 6.8 6.6 6.2 10.1 2.2 7.6 7.7 6.1 9.2 12.3 4.2 5.7 6.9 3.4 6.9 9.2 12.0 5.3 8.6 5.4 8.6 4.8 6.8 10.2 5.1 16.0 4.9 6.5 7.4 4.7 5.3 5.0 6.3 6.3 9.6 3.7 4.8 8.0 9.8 6.0 7.5 5.0 8.1 5.5 9.4 3.9 8.7 7.5 8.6 5.3 3.3 9.4 11.0 9.2 2.6 4.1 4.6 31.5 7.3 18.3 17.0 10.2 31.5 14.9 17.0 18.0 6.4 13.0 20.0 17.2 16.8 20.3 11.2 8.7 14.2 6.9 2.6 3.4 9.0 3.6 2.9 3.9 3.2 2.9 3.5 3.3 3.3 6.4 15.7 16.0 9.4 17.0 30.1 24.5 16.4 20.1 27.9 24.8 12.9 10.4 12.1 11.5 17.6 18.4 35.5 7.7 27.5 14.9 7.9 10.0 40.2 20.0 13.6 15.4 13.9 27.8 32.6 5.6 8.3 18.0 17.3 9.7 19.0 10.2 16.8 13.1 9.2 15.2 30.0 12.1 6.1 15.8 23.6 62.8 21.8 19.1 23.2 16.9 15.7 23.2 23.7 36.7 40.4 10.3 12.7 17.7 27.0 12.6 13.1 8.5 32.3 23.4 13.1 14.6 19.8 10.8 5.1 19.4 30.1 14.1 38.6 7.7 9.5 15.8 KLHL36 "C16orf44, FLJ12543" ENSG00000135686 "Kelch like family member 36" Q8N4N3 16 84648511-84667686 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023423 Approved Approved Cytosol NA NA "Cluster 30: Non-specific - Translation" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "HPA023423: AB_10962985" "unprognostic (6.50e-2)" "unprognostic (2.41e-2)" "unprognostic (2.35e-1)" "unprognostic (5.84e-2)" "unprognostic (1.49e-1)" "unprognostic (1.20e-1)" "unprognostic (1.58e-1)" "unprognostic (2.90e-1)" "unprognostic (5.25e-2)" "unprognostic (2.59e-2)" "prognostic favorable (9.81e-5)" "unprognostic (3.79e-3)" "prognostic favorable (5.52e-10)" "unprognostic (3.48e-1)" "unprognostic (1.44e-1)" "unprognostic (8.47e-2)" "unprognostic (1.67e-3)" 9.3 6.4 7.2 6.1 5.8 13.4 7.7 4.2 7.0 5.7 10.0 7.0 6.8 6.6 2.1 8.9 6.8 3.9 9.8 9.0 4.9 6.9 11.3 8.6 7.7 6.4 4.4 8.7 11.4 8.9 6.1 4.6 3.6 6.6 3.2 1.9 7.6 5.3 5.1 8.1 9.0 4.0 3.9 9.3 8.4 13.8 5.9 4.3 8.8 4.5 4.9 8.2 7.1 4.0 18.9 19.9 5.0 11.9 5.4 8.8 18.9 13.9 9.7 5.8 2.8 17.3 12.7 13.2 18.2 11.3 5.9 20.6 5.5 13.4 4.0 8.1 8.0 4.4 6.7 10.9 7.2 5.4 12.2 8.4 11.2 6.7 8.3 8.6 8.7 4.3 14.3 2.1 6.0 28.7 0.8 8.3 7.6 8.1 8.2 18.1 5.8 6.3 11.1 17.2 5.9 4.4 16.6 4.7 8.8 6.0 17.7 16.6 16.9 7.6 12.9 8.2 8.7 7.1 10.2 22.7 10.3 7.3 22.2 3.5 2.7 6.3 3.2 1.7 2.8 4.5 5.9 4.7 3.7 3.7 6.9 5.0 3.2 2.3 2.0 3.4 3.4 2.8 7.2 5.8 4.2 7.0 9.0 4.9 6.4 4.4 3.6 3.9 5.9 4.0 18.5 19.2 16.2 8.5 24.6 15.9 45.3 23.9 15.9 25.8 23.3 15.7 26.5 32.9 16.8 22.0 35.5 23.7 19.3 28.3 5.9 24.5 41.4 13.8 12.3 19.6 18.6 6.5 11.8 14.5 11.7 20.9 16.3 21.4 7.0 22.7 19.2 21.9 19.3 26.9 10.6 23.3 26.4 21.2 17.6 14.7 23.3 18.0 21.4 15.9 22.4 10.5 18.6 7.5 8.5 22.8 20.0 25.2 10.8 56.0 37.0 28.1 16.3 23.0 32.9 21.7 24.9 21.7 6.1 19.3 17.6 19.3 26.8 12.8 21.3 39.8 KLHL9 "FLJ13568, KIAA1354" ENSG00000198642 "Kelch like family member 9" Q9P2J3 9 21329665-21335404 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046039, HPA059901" Approved Approved Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 5: Breast - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 43: Cardiomyocytes - Nuclear processes" Cytosol "HPA046039: AB_2679514, HPA059901: AB_2684155" "unprognostic (7.82e-2)" "unprognostic (4.36e-1)" "unprognostic (1.84e-1)" "unprognostic (1.37e-1)" "unprognostic (4.89e-1)" "unprognostic (1.87e-1)" "unprognostic (1.32e-1)" "unprognostic (2.24e-2)" "unprognostic (8.23e-2)" "unprognostic (2.95e-1)" "unprognostic (4.52e-2)" "unprognostic (9.06e-2)" "prognostic favorable (9.43e-10)" "unprognostic (2.87e-2)" "unprognostic (2.85e-1)" "unprognostic (2.91e-1)" "unprognostic (3.33e-3)" 11.2 10.2 7.8 10.9 8.4 8.9 16.8 10.2 9.2 14.9 8.4 12.0 7.1 15.5 14.6 10.4 13.3 10.2 7.9 7.3 9.1 14.3 10.9 11.2 12.1 8.0 7.9 19.6 10.8 12.8 5.2 16.8 8.1 15.7 12.1 17.7 12.2 11.3 4.6 8.4 10.4 14.2 8.7 15.2 13.4 7.2 8.0 14.4 16.0 8.4 11.5 10.9 7.1 12.3 12.3 14.7 32.6 17.7 41.3 40.7 7.1 22.5 22.9 16.7 18.8 5.6 9.5 5.5 14.2 33.1 16.8 6.6 19.2 22.0 20.6 30.7 14.0 0.0 27.4 14.5 28.7 9.8 6.5 40.2 23.3 13.1 21.1 27.3 25.8 0.0 0.0 7.0 38.6 7.8 20.4 33.9 13.4 12.7 12.4 0.0 14.3 6.6 20.8 15.1 10.3 19.6 13.0 11.6 14.3 30.0 21.0 0.0 31.2 0.1 11.7 9.4 13.2 7.6 11.2 5.7 0.0 10.1 11.5 8.4 6.0 16.5 4.8 6.8 5.5 3.1 5.9 4.4 4.7 2.3 7.1 4.9 1.9 6.2 7.2 3.5 4.5 4.6 7.8 8.4 10.2 9.2 7.3 9.1 8.0 7.9 8.1 8.7 8.0 12.3 20.3 25.6 20.5 9.1 12.2 10.3 34.3 15.4 22.8 27.3 14.8 12.4 17.9 17.2 25.9 16.5 18.8 16.4 12.7 19.5 11.7 14.8 0.8 12.1 26.2 20.2 27.6 10.5 14.2 15.3 7.8 22.6 25.5 12.7 12.0 24.6 37.9 23.1 15.4 18.5 17.0 22.0 22.4 22.8 8.4 1.9 21.5 14.7 17.8 20.6 14.7 20.1 9.2 15.1 23.8 12.2 13.9 24.0 16.3 25.2 13.7 19.3 20.8 21.4 13.1 20.1 22.0 13.4 9.7 19.5 10.4 10.0 17.2 18.7 16.9 21.0 KPNA5 "IPOA6, SRP6" ENSG00000196911 "Karyopherin subunit alpha 5" O15131 6 116681187-116741867 "Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 44.1" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 227.6;Alveolar cells type 2: 240.9;granulocytes: 129.3;Respiratory ciliated cells: 143.6;Spermatocytes: 173.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026464, HPA054037" Enhanced Supported Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" Cytosol "CAB026464: , HPA054037: AB_2682351" "unprognostic (9.64e-2)" "unprognostic (1.49e-1)" "unprognostic (1.72e-2)" "unprognostic (3.56e-1)" "unprognostic (6.60e-3)" "unprognostic (6.98e-2)" "unprognostic (1.75e-3)" "unprognostic (5.19e-2)" "unprognostic (1.10e-1)" "unprognostic (6.12e-2)" "unprognostic (1.51e-3)" "unprognostic (3.02e-1)" "unprognostic (6.12e-2)" "unprognostic (8.00e-2)" "unprognostic (4.79e-1)" "unprognostic (7.89e-2)" "unprognostic (1.43e-1)" 4.1 5.4 7.0 5.0 8.2 7.1 6.1 15.9 13.0 6.4 1.9 3.4 3.2 9.4 3.7 5.0 8.1 5.2 4.6 7.6 5.9 5.0 2.5 6.0 8.9 7.7 4.4 19.0 2.5 6.4 4.7 4.4 8.4 6.7 3.2 18.9 4.1 5.3 13.8 3.5 3.6 6.8 3.6 6.5 3.6 44.1 4.8 8.9 10.2 12.7 6.3 4.8 3.6 11.7 2.9 1.7 12.0 7.5 4.4 8.5 4.9 4.2 11.7 7.4 10.5 8.1 3.0 10.8 5.6 4.6 8.4 4.7 6.3 3.7 9.2 6.8 18.1 10.1 5.6 4.5 5.5 7.8 6.0 7.7 2.2 9.0 5.6 8.6 8.3 10.3 15.0 4.6 8.3 3.9 12.5 5.5 5.4 2.0 4.7 10.1 3.9 3.0 5.5 5.5 12.8 11.9 3.2 2.7 4.6 7.7 5.3 7.9 6.8 3.0 6.2 3.2 7.5 11.6 13.4 12.2 3.8 5.6 6.4 27.6 4.7 6.4 13.1 5.1 16.3 25.3 14.8 15.7 2.7 26.6 24.1 17.9 1.3 11.2 6.9 16.7 12.1 4.1 7.0 8.2 15.9 13.0 7.6 5.9 7.7 4.4 8.4 3.6 4.8 11.7 12.5 227.6 240.9 63.0 35.2 13.6 7.1 8.9 13.6 50.9 12.8 13.3 17.1 10.0 118.6 9.2 29.2 4.2 24.2 1.6 9.8 6.1 80.3 22.0 13.0 28.8 33.7 7.6 63.7 5.6 1.8 30.5 6.1 7.9 129.3 18.8 20.3 4.7 4.4 47.1 70.9 7.1 8.2 9.1 9.5 15.2 17.7 21.5 10.6 41.2 7.6 34.7 10.3 64.3 56.7 6.0 1.5 16.6 15.8 8.9 2.4 6.5 143.6 38.8 13.1 16.8 15.4 173.4 10.6 8.8 8.9 3.3 31.9 15.9 4.2 3.8 KRT18 ENSG00000111057 "Keratin 18" P05783 12 52948871-52952906 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Host-virus interaction" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 3698.8;Ductal cells: 6583.8;Exocrine glandular cells: 4826.1;Extravillous trophoblasts: 5496.7;Pancreatic endocrine cells: 6071.5;Syncytiotrophoblasts: 7643.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "basophil: 76.7" "Lineage enriched" "Detected in many" 7 "granulocytes: 76.7" "Cell line enhanced" "Detected in many" "A549: 5639.4;BEWO: 3818.0;CACO-2: 6249.4;CAPAN-2: 4576.4;MCF7: 8470.0;SK-BR-3: 4583.8" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 12.1" "CAB000008, CAB000030, HPA001605" Enhanced Supported Cytosol NA NA 140000000 "Cluster 38: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 1: Pancreatic cells - Digestion" Cytosol "CAB000008: , CAB000030: , HPA001605: AB_2666381" "unprognostic (1.98e-1)" "unprognostic (1.03e-1)" "unprognostic (3.31e-1)" "unprognostic (1.63e-2)" "unprognostic (1.25e-1)" "unprognostic (7.26e-3)" "unprognostic (4.09e-3)" "prognostic unfavorable (5.06e-4)" "unprognostic (8.81e-2)" "unprognostic (4.17e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (3.05e-1)" "unprognostic (1.04e-1)" "unprognostic (1.27e-1)" "unprognostic (2.19e-1)" "unprognostic (1.11e-2)" "unprognostic (1.13e-2)" 170.3 29.0 2.6 77.5 1.4 1.5 209.8 5.3 1.6 243.5 34.8 424.1 324.3 27.8 226.0 118.4 193.5 180.6 38.3 2.2 6.9 247.2 519.5 177.8 8.6 26.1 4.3 16.4 570.2 79.5 251.9 474.5 30.3 183.3 492.3 0.6 323.4 129.5 2.1 44.5 370.7 23.4 2.5 28.5 289.9 8.3 13.9 10.3 244.1 1.4 27.8 199.7 62.2 2.5 2065.1 5639.4 1.1 7.9 0.7 1.1 3818.0 313.3 349.5 368.4 104.6 6249.4 4576.4 1.4 839.8 318.4 196.5 487.2 79.1 2228.5 217.9 2.6 138.2 19.4 865.7 1743.9 942.1 0.6 1.3 13.6 202.9 323.8 437.1 1046.9 399.0 3.4 511.4 0.2 0.3 8470.0 3.8 37.3 471.0 2740.1 457.9 3.0 0.3 236.1 1803.3 1144.9 65.6 3.7 512.7 4583.8 18.8 2696.0 2446.8 6.6 137.9 5.0 441.8 6.9 68.3 1.1 7.3 4.3 0.9 1.2 36.4 76.7 0.3 2.4 0.6 0.2 2.2 4.6 4.5 1.2 2.2 7.4 11.1 4.1 3.2 2.5 0.0 0.1 0.4 2.9 2.6 1.4 5.3 1.6 2.2 6.9 26.1 4.3 30.3 2.5 13.9 2.5 14.4 862.2 286.4 0.3 29.8 14.8 1605.7 912.1 447.3 0.1 814.6 615.6 5.3 1252.5 877.3 623.5 0.0 3698.8 14.2 1942.9 275.9 6583.8 1.0 462.3 60.3 77.8 642.3 15.4 0.0 4826.1 5496.7 203.5 971.5 742.4 48.9 51.2 57.1 610.9 308.3 1.7 0.0 2492.6 1969.3 9.8 13.8 3.8 10.5 28.3 208.1 1.0 41.5 6.2 0.0 0.0 0.0 6071.5 2164.1 0.0 13.7 1205.1 1912.3 718.5 500.8 0.6 0.0 0.6 298.6 2.7 26.0 395.7 6.7 7643.5 38.1 45.0 1635.0 1512.1 KRT20 "CK20, K20, MGC35423" ENSG00000171431 "Keratin 20" P35900 17 40875889-40885242 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 646.9" "Group enriched" "Detected in some" 6 "Distal enterocytes: 1328.5;Intestinal goblet cells: 421.7;Paneth cells: 1606.6;Proximal enterocytes: 1107.3" "Group enriched" "Detected in many" 6 "colorectal cancer: 159.5;stomach cancer: 52.7;urothelial cancer: 99.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NB-4: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000032, HPA024309, HPA024684, HPA027236" Enhanced Supported Cytosol NA NA 30000000 "Cluster 9: Intestine - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB000032: AB_2133718, HPA024309: AB_1852220, HPA024684: AB_1852222, HPA027236: AB_1852224" "unprognostic (3.49e-1)" "unprognostic (3.13e-1)" "unprognostic (1.71e-1)" "unprognostic (6.38e-3)" "unprognostic (5.12e-2)" "unprognostic (2.66e-3)" "prognostic unfavorable (7.05e-4)" "unprognostic (2.63e-2)" "unprognostic (4.87e-3)" "unprognostic (2.37e-2)" "prognostic unfavorable (1.32e-4)" "unprognostic (5.71e-2)" "unprognostic (6.30e-2)" "unprognostic (7.27e-2)" 1.3 0.0 0.0 49.9 0.0 0.0 1.6 0.0 0.0 0.1 0.0 597.7 295.9 2.1 0.0 0.3 0.3 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 480.1 0.0 0.0 1.2 0.0 0.1 646.9 27.0 0.0 0.0 124.9 0.0 0.0 0.0 0.0 0.0 0.0 21.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 4.4 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1328.5 0.0 0.1 0.0 0.0 0.0 0.0 43.9 0.0 0.1 0.0 0.0 0.0 115.7 0.1 13.4 0.0 0.0 0.0 0.1 0.0 0.0 421.7 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1606.6 0.0 0.6 1.9 1107.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.6 0.0 160.4 1.4 KRT86 "Hb6, KRTHB6, MNX" ENSG00000170442 "Keratin 86" O43790 12 52249300-52309163 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "skin 1: 150.5" "Group enriched" "Detected in many" 4 "dendritic cells: 33.1;Early spermatids: 35.5;Late spermatids: 24.3;NK-cells: 11.3;T-cells: 14.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 9 "basophil: 87.5" "Lineage enriched" "Detected in many" 9 "granulocytes: 87.5" "Cell line enhanced" "Detected in many" "A-431: 24.9;A549: 25.7;MCF7: 51.6;RPMI-8226: 32.5;U-251 MG: 14.5" "HPA039798, HPA049778" Supported Approved Cytosol NA NA 160000000 "Cluster 38: Basophils - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA039798: AB_10674986, HPA049778: AB_2680877" "unprognostic (4.52e-2)" "unprognostic (6.83e-2)" "unprognostic (3.16e-2)" "unprognostic (2.20e-1)" "unprognostic (1.78e-2)" "unprognostic (2.61e-2)" "unprognostic (6.49e-2)" "unprognostic (1.06e-2)" "unprognostic (1.98e-1)" "unprognostic (2.59e-2)" "unprognostic (1.37e-1)" "unprognostic (1.74e-1)" "unprognostic (9.19e-2)" "unprognostic (1.09e-1)" "unprognostic (1.65e-1)" "unprognostic (1.24e-1)" "unprognostic (7.22e-2)" 1.2 0.5 0.5 0.2 0.7 2.6 0.5 0.0 0.5 0.2 0.0 0.5 0.4 0.4 0.5 0.1 0.7 0.4 0.1 0.8 0.2 0.2 0.1 0.7 0.0 0.3 0.4 0.1 2.1 0.1 0.1 0.4 0.4 0.3 0.0 0.1 3.8 0.3 0.3 150.5 0.3 0.1 0.2 0.1 0.2 4.0 0.5 0.2 4.1 0.0 0.1 0.8 0.2 1.2 24.9 25.7 0.0 0.0 0.0 0.0 0.3 0.9 0.7 0.3 0.1 0.3 1.3 0.0 1.1 0.0 0.5 1.5 0.0 4.5 0.1 10.9 0.0 0.0 5.4 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.5 12.7 0.0 0.0 0.0 1.8 0.0 51.6 0.0 3.0 0.1 0.2 6.1 0.0 0.0 32.5 0.4 3.2 2.9 0.0 4.5 2.0 2.0 0.0 1.4 0.0 0.8 0.0 1.3 0.1 14.5 0.0 0.0 0.0 0.0 5.3 0.0 87.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.5 0.5 0.7 0.0 0.5 0.8 0.2 0.3 0.4 0.4 0.2 0.5 1.2 0.1 0.0 0.6 0.0 0.3 0.6 2.9 2.0 0.0 0.4 2.8 3.4 0.4 2.8 3.1 0.0 0.0 0.1 33.1 0.2 0.0 2.1 35.5 3.6 0.8 0.2 0.0 0.0 0.5 5.1 1.6 0.3 1.1 4.9 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 2.0 0.0 1.1 24.3 0.3 0.3 1.8 0.0 0.0 0.2 11.3 0.0 0.5 2.9 0.0 0.0 2.1 2.7 0.0 0.6 1.9 0.3 0.0 1.0 0.4 0.8 0.4 0.0 0.1 1.2 14.2 0.0 0.0 3.5 KYAT1 "CCBL1, GTK, KATI" ENSG00000171097 "Kynurenine aminotransferase 1" Q16773 9 128832942-128882494 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Aminotransferase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in some" 6 "Granulosa cells: 45.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA021176, HPA021177, HPA027736" Approved Supported Cytosol NA NA 22000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA021176: AB_1846120, HPA021177: AB_1846119, HPA027736: AB_10611818" "unprognostic (6.51e-2)" "unprognostic (8.67e-3)" "unprognostic (1.05e-2)" "unprognostic (5.98e-3)" "unprognostic (2.15e-2)" "unprognostic (5.44e-2)" "unprognostic (2.91e-2)" "unprognostic (1.12e-2)" "unprognostic (2.47e-1)" "unprognostic (8.60e-3)" "unprognostic (1.43e-1)" "unprognostic (3.65e-2)" "unprognostic (3.10e-2)" "unprognostic (5.79e-2)" "unprognostic (2.03e-1)" "unprognostic (1.08e-1)" "unprognostic (1.98e-1)" 3.5 4.7 12.3 3.6 13.3 2.3 4.0 13.0 15.5 7.2 10.6 4.7 2.5 5.8 2.9 5.3 6.4 2.7 10.3 12.1 11.8 7.8 12.7 3.6 5.0 13.2 12.3 6.2 3.1 5.5 8.7 2.5 12.8 7.4 1.3 7.5 4.2 4.3 12.6 7.7 4.2 3.1 12.3 5.4 4.9 5.6 12.9 8.9 6.1 8.7 4.8 7.2 6.7 18.0 4.8 9.8 9.3 10.6 6.9 11.4 3.0 5.5 8.0 6.2 8.0 3.9 9.7 8.3 2.9 4.6 7.0 14.9 13.9 11.1 9.3 10.0 7.3 5.7 27.7 9.6 7.7 5.0 1.9 4.5 7.1 7.1 7.7 21.8 11.3 22.7 8.2 9.0 8.5 3.1 14.0 3.4 15.2 18.3 7.6 16.4 6.4 18.9 8.7 1.7 10.5 7.4 9.9 2.9 6.2 12.8 6.6 1.6 7.0 4.6 7.9 7.1 5.0 15.2 11.0 11.6 9.6 8.3 3.2 0.1 1.4 2.9 5.1 1.8 4.5 7.7 5.7 6.0 5.5 3.3 5.9 6.7 0.9 3.3 2.9 2.4 7.0 3.3 12.3 13.3 13.0 15.5 12.1 11.8 13.2 12.3 12.8 12.3 12.9 18.0 2.6 0.0 1.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 2.0 1.5 0.0 0.0 0.6 0.0 0.0 5.0 0.9 0.0 3.9 1.6 0.0 2.6 3.3 0.7 0.0 0.0 0.0 0.2 2.4 0.7 0.0 4.2 0.0 45.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.3 0.0 0.0 7.3 2.9 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 2.1 1.3 1.3 0.0 0.0 LAMTOR5 "HBXIP, MGC71071, XIP" ENSG00000134248 "Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5" O43504 1 110401249-110407942 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1113.2;Proximal tubular cells: 2532.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006812 Approved Supported Cytosol NA NA 150000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA006812: AB_1079040" "unprognostic (1.18e-1)" "unprognostic (1.93e-1)" "unprognostic (2.29e-1)" "unprognostic (3.54e-3)" "unprognostic (2.75e-1)" "unprognostic (5.29e-3)" "prognostic unfavorable (2.60e-4)" "unprognostic (9.97e-2)" "unprognostic (7.58e-2)" "prognostic favorable (7.23e-4)" "unprognostic (2.80e-1)" "unprognostic (2.93e-1)" "unprognostic (1.65e-2)" "unprognostic (3.77e-2)" "unprognostic (3.80e-3)" "prognostic favorable (5.52e-4)" "unprognostic (6.66e-2)" 143.6 134.9 152.2 79.5 156.3 250.3 127.7 167.7 179.0 107.7 168.0 108.3 85.7 86.2 162.6 121.0 93.2 101.9 269.7 150.9 163.6 433.9 150.2 115.2 114.1 159.6 155.4 121.0 95.3 192.3 141.2 120.7 157.9 109.4 110.9 140.0 100.1 77.6 260.3 98.7 102.2 81.5 165.1 126.0 127.8 88.6 161.4 102.2 107.8 277.3 122.6 124.2 109.4 168.1 272.1 223.2 197.3 118.5 325.3 245.3 196.1 224.4 176.5 186.8 176.6 196.0 130.0 214.5 233.0 220.9 228.4 107.5 203.4 189.2 229.8 231.4 227.9 157.7 257.1 402.1 247.1 227.7 188.0 216.3 287.3 193.9 122.6 236.2 227.7 156.9 189.3 196.0 275.8 443.0 208.7 274.7 140.1 151.8 366.9 141.9 355.1 164.2 439.0 302.0 145.4 189.6 198.8 287.7 516.4 169.5 111.0 317.3 217.8 140.5 182.9 355.7 214.4 204.5 250.7 277.2 459.1 225.6 329.6 295.4 223.1 485.8 125.9 229.5 112.1 345.3 146.6 137.6 187.9 322.3 127.1 134.4 347.7 149.2 225.0 321.5 181.1 250.6 152.2 156.3 167.7 179.0 150.9 163.6 159.6 155.4 157.9 165.1 161.4 168.1 131.2 160.3 174.4 16.3 208.2 307.8 284.1 661.5 101.3 111.0 186.0 197.9 597.6 211.6 371.9 445.1 25.0 424.5 141.5 225.1 1113.2 389.2 67.5 215.8 141.8 193.1 222.3 158.9 15.4 331.0 370.7 194.0 99.9 191.1 146.4 97.0 133.9 311.9 424.8 89.2 17.6 302.6 449.6 154.4 189.2 112.8 264.7 175.3 350.4 18.7 320.9 297.9 137.0 9.5 23.3 403.9 296.4 239.2 100.6 360.9 315.4 2532.5 340.9 150.5 170.9 168.2 185.2 297.9 361.3 121.3 322.5 500.5 125.7 163.2 252.0 441.8 LAPTM5 ENSG00000162511 "Lysosomal protein transmembrane 5" Q13571 1 30732469-30757774 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1285.7;lymphoid tissue: 672.2" "Group enriched" "Detected in many" 4 "B-cells: 872.9;dendritic cells: 340.2;granulocytes: 639.8;Hofbauer cells: 1150.4;Kupffer cells: 942.2;Langerhans cells: 489.6;Macrophages: 925.0;monocytes: 446.1;NK-cells: 562.3;T-cells: 432.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 554.0;HEL: 1053.2;HL-60: 676.4;HMC-1: 2382.4;REH: 785.2;U-698: 898.1;U-937: 542.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051293 Approved Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" Cytosol "HPA051293: AB_2681424" "unprognostic (3.12e-2)" "prognostic favorable (3.40e-4)" "unprognostic (6.86e-2)" "unprognostic (4.05e-3)" "unprognostic (1.63e-1)" "unprognostic (8.45e-2)" "unprognostic (1.43e-1)" "unprognostic (3.76e-1)" "unprognostic (1.22e-3)" "unprognostic (2.30e-1)" "unprognostic (6.75e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (5.89e-5)" "unprognostic (9.47e-2)" "unprognostic (8.18e-3)" "unprognostic (5.98e-2)" "unprognostic (3.94e-2)" 144.7 82.1 47.6 443.0 49.7 1285.7 60.4 49.7 90.4 53.1 55.7 82.2 68.1 27.3 16.7 49.5 46.8 137.9 31.6 45.2 62.7 30.5 98.6 284.9 672.2 82.4 67.3 16.4 30.2 21.8 22.6 145.2 75.8 31.5 90.6 5.9 38.5 30.9 9.2 24.0 155.9 93.5 69.2 491.1 72.9 10.9 81.1 298.3 38.5 20.9 636.5 161.1 22.8 114.9 1.2 0.0 1.7 0.0 0.1 0.1 0.6 0.9 0.3 0.5 0.1 0.7 1.2 554.0 56.0 1.7 1.9 2.2 0.0 0.8 0.5 62.3 0.0 1053.2 0.0 1.6 0.9 676.4 2382.4 0.6 1.2 0.6 4.1 0.3 124.2 70.7 13.8 34.0 8.8 0.0 117.5 142.2 0.7 0.0 0.0 785.2 99.6 391.6 0.8 0.1 0.6 0.4 1.3 1.3 1.1 1.0 0.5 422.2 145.3 0.6 3.0 0.6 3.4 2.7 0.7 898.1 3.1 542.8 1.8 1094.2 1522.8 1446.7 538.5 1046.1 616.3 823.6 485.5 502.8 825.7 1089.4 481.2 481.2 1709.5 327.0 1075.7 392.7 656.9 2740.4 47.6 49.7 49.7 90.4 45.2 62.7 82.4 67.3 75.8 69.2 81.1 114.9 62.9 25.6 100.4 0.0 872.9 23.8 1.1 1.3 4.0 0.0 6.2 10.4 5.5 14.3 13.9 3.7 0.0 5.8 340.2 0.8 0.0 1.2 2.0 1.4 0.9 60.2 1.2 78.2 0.2 0.7 8.4 12.3 10.2 1.1 639.8 0.2 47.2 9.4 1150.4 0.0 0.8 0.9 0.0 942.2 489.6 4.9 1.5 925.0 49.8 43.1 446.1 0.3 562.3 0.5 0.5 1.4 0.2 0.4 144.8 0.9 0.5 3.0 11.4 1.3 0.0 4.1 5.6 0.3 1.1 1.8 20.0 8.9 432.7 18.2 2.4 1.9 LARP1B "DKFZp434K245, DKFZp686E0316, FLJ10378, LARP2" ENSG00000138709 "La ribonucleoprotein 1B" Q659C4 4 128061286-128222931 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 393.1;Late spermatids: 449.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036280 Approved Approved Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Cytosol "HPA036280: AB_10673126" "unprognostic (1.84e-1)" "unprognostic (7.55e-2)" "unprognostic (9.39e-3)" "unprognostic (4.87e-2)" "unprognostic (2.26e-1)" "unprognostic (2.22e-1)" "unprognostic (1.79e-1)" "unprognostic (2.63e-1)" "unprognostic (6.39e-2)" "unprognostic (3.36e-2)" "unprognostic (3.54e-2)" "unprognostic (1.38e-1)" "prognostic favorable (5.13e-5)" "unprognostic (8.46e-2)" "unprognostic (5.94e-2)" "unprognostic (2.08e-1)" "unprognostic (7.50e-2)" 10.5 8.2 5.1 8.0 6.1 14.4 11.5 8.5 9.7 11.5 2.1 14.8 14.6 8.9 24.1 11.1 9.6 9.1 11.6 5.9 5.4 14.2 50.7 9.9 6.3 3.5 4.2 10.3 35.6 16.3 12.9 10.5 4.4 11.0 16.3 11.0 13.8 11.7 18.2 11.1 15.5 8.3 2.1 6.2 15.4 55.8 6.0 6.5 13.6 13.3 9.3 13.2 9.9 8.6 21.5 7.4 13.2 16.7 13.7 15.5 26.8 18.0 19.9 16.7 10.7 16.9 16.5 26.1 24.6 17.8 12.7 8.3 32.7 19.9 19.9 24.7 20.9 20.9 13.0 41.5 29.7 40.3 8.2 8.1 28.7 13.4 49.0 16.0 19.8 19.4 37.1 42.4 9.6 25.1 35.2 23.1 15.2 33.0 11.9 19.4 20.3 29.8 19.1 16.4 39.1 15.5 15.6 35.7 16.8 17.5 10.5 17.4 16.1 10.7 11.8 17.5 18.1 55.9 22.7 30.1 13.8 30.7 11.5 0.2 2.1 1.3 1.7 1.6 3.1 1.6 1.9 2.2 2.5 1.4 1.5 1.7 0.5 2.6 1.7 4.6 1.7 0.8 5.1 6.1 8.5 9.7 5.9 5.4 3.5 4.2 4.4 2.1 6.0 8.6 18.4 35.3 35.6 46.0 19.9 27.8 25.7 11.7 10.8 37.0 34.9 18.7 30.2 40.0 32.5 20.2 52.1 31.4 15.2 52.2 13.7 22.1 393.1 41.9 32.3 17.3 34.0 25.0 139.1 29.9 23.2 23.4 29.6 62.6 20.8 12.5 15.0 154.6 11.9 23.5 115.6 115.2 18.3 15.7 16.3 449.5 36.4 15.5 17.8 19.7 16.7 17.5 20.6 55.8 51.8 31.3 36.2 19.9 54.5 46.4 37.4 63.2 29.0 71.5 19.7 20.7 23.1 138.3 21.9 25.3 34.7 51.4 14.3 8.4 55.1 30.6 LARP4B "KIAA0217, LARP5" ENSG00000107929 "La ribonucleoprotein 4B" Q92615 10 806914-931705 "Predicted intracellular proteins, Predicted membrane proteins" "Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036566, HPA042738" Approved Enhanced Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Cytosol "HPA036566: AB_10673624, HPA042738: AB_2678137" "unprognostic (3.02e-3)" "unprognostic (1.43e-1)" "unprognostic (9.77e-2)" "unprognostic (4.80e-2)" "unprognostic (2.00e-2)" "unprognostic (3.13e-3)" "prognostic unfavorable (1.70e-4)" "unprognostic (8.95e-2)" "unprognostic (2.74e-1)" "unprognostic (1.87e-2)" "unprognostic (2.70e-2)" "unprognostic (1.65e-1)" "unprognostic (1.40e-1)" "unprognostic (8.10e-3)" "unprognostic (1.62e-1)" "unprognostic (6.47e-2)" "unprognostic (2.54e-2)" 14.3 19.9 13.1 17.2 13.3 18.5 13.6 15.3 17.4 13.4 20.9 17.0 19.4 13.1 10.3 25.2 13.3 12.8 22.2 16.4 14.9 13.8 13.0 20.2 22.1 16.0 12.0 13.0 16.5 17.1 12.7 15.1 15.6 16.2 15.6 14.5 16.8 12.3 38.7 22.3 18.5 10.9 12.1 19.4 21.9 18.9 13.2 16.0 22.2 22.3 19.7 15.9 16.7 14.1 50.0 42.7 21.7 24.5 19.0 19.1 32.2 33.0 15.7 35.6 34.2 58.1 56.4 59.9 12.0 33.0 10.6 51.6 38.5 28.0 30.5 38.1 27.9 51.6 29.5 33.9 31.3 37.3 42.5 21.2 31.7 36.8 20.4 19.9 24.8 28.8 65.5 39.3 28.9 50.9 53.0 33.8 23.2 49.5 16.5 36.1 18.7 41.5 28.6 38.5 21.4 30.2 32.5 62.5 25.4 21.1 59.3 35.6 34.4 27.6 7.2 87.8 34.2 39.2 51.2 58.3 30.5 30.0 17.6 11.4 8.2 9.7 5.4 9.0 5.7 4.2 6.0 6.2 7.3 5.2 5.7 6.0 8.0 5.4 7.9 8.3 6.1 3.9 13.1 13.3 15.3 17.4 16.4 14.9 16.0 12.0 15.6 12.1 13.2 14.1 23.7 51.3 62.1 59.4 22.4 30.3 15.6 16.2 23.9 20.5 21.6 15.4 43.5 28.6 30.7 23.9 27.1 17.2 24.6 38.5 5.9 17.4 14.7 42.0 24.5 21.2 13.8 22.7 87.7 16.3 13.2 19.4 44.9 43.4 7.6 31.0 14.6 19.1 21.5 23.5 84.1 35.1 18.3 34.7 25.3 7.1 17.4 30.3 17.8 83.4 33.4 15.7 14.4 65.9 71.6 33.2 27.2 24.0 25.5 27.0 32.5 16.2 33.4 22.4 26.3 23.4 18.3 27.8 23.8 28.8 42.6 46.2 20.7 26.1 34.7 35.6 LAYN "FLJ30977, FLJ31092" ENSG00000204381 Layilin Q6UX15 11 111540280-111561745 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Prostatic glandular cells: 233.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 22 "myeloid DC: 11.2;T-reg: 13.4" "Group enriched" "Detected in many" 123 "dendritic cells: 11.2;T-cells: 13.4" "Cell line enhanced" "Detected in many" "BJ: 150.7;BJ hTERT+: 153.7;BJ hTERT+ SV40 Large T+ RasG12V: 96.7;fHDF/TERT166: 95.1;HSkMC: 88.8;hTERT-RPE1: 94.0;U-138 MG: 108.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA040087 Approved Approved Cytosol NA NA 340000 "Cluster 35: T-regs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA040087: AB_10793927" "unprognostic (2.27e-1)" "unprognostic (3.03e-2)" "unprognostic (2.22e-3)" "unprognostic (1.96e-1)" "unprognostic (3.90e-2)" "unprognostic (1.83e-2)" "unprognostic (5.62e-3)" "unprognostic (1.99e-1)" "unprognostic (1.38e-1)" "unprognostic (7.75e-3)" "unprognostic (4.47e-2)" "unprognostic (1.18e-1)" "unprognostic (1.61e-2)" "unprognostic (5.01e-2)" "unprognostic (1.65e-1)" "unprognostic (2.91e-2)" "unprognostic (1.35e-2)" 10.7 2.0 15.6 5.7 21.4 1.0 8.5 15.7 19.6 15.6 13.7 29.2 3.8 15.8 10.1 4.7 17.7 17.0 7.0 16.6 17.1 5.7 0.9 11.3 7.1 17.4 19.7 39.1 2.0 6.4 6.2 14.1 16.3 14.6 3.3 0.8 5.5 17.0 6.1 2.6 10.6 22.5 14.2 8.2 13.1 4.4 18.0 10.3 27.4 6.1 5.0 8.8 12.2 23.7 0.4 3.9 0.8 0.0 25.4 48.0 7.6 150.7 153.7 71.0 96.7 0.2 0.1 0.0 1.4 95.1 18.7 3.2 9.9 0.7 74.2 0.2 0.5 0.8 0.0 0.2 41.7 0.0 0.2 88.8 0.0 30.8 0.2 94.0 0.9 0.0 0.0 0.1 29.4 0.0 0.1 0.1 4.8 0.0 0.0 0.0 11.4 0.2 0.6 0.0 4.9 18.9 0.5 0.2 0.4 34.9 0.1 0.7 0.6 108.8 81.2 1.0 74.3 0.0 0.0 0.2 14.4 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 11.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 13.4 0.4 15.6 21.4 15.7 19.6 16.6 17.1 17.4 19.7 16.3 14.2 18.0 23.7 22.2 19.2 2.8 0.3 0.3 2.2 48.8 44.8 0.6 0.4 0.7 15.0 2.7 2.8 23.3 0.0 0.0 1.6 2.6 0.0 0.0 6.5 2.5 3.9 7.7 50.9 0.0 2.7 0.3 0.2 2.1 13.1 0.0 0.9 1.3 9.6 6.8 0.1 0.7 0.0 1.4 0.0 6.1 0.6 13.6 1.8 22.7 1.2 0.0 2.8 0.6 0.2 0.0 4.0 30.1 0.8 0.0 55.3 2.8 233.0 0.0 0.2 32.0 0.2 32.9 2.6 17.3 0.1 2.3 0.1 2.3 0.5 14.5 11.2 0.0 50.3 LCMT2 "KIAA0547, MGC9534, PPM2, TYW4" ENSG00000168806 "Leucine carboxyl methyltransferase 2" O60294 15 43323649-43330582 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 23.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039401 Approved Approved Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol "HPA039401: AB_10805478" "unprognostic (4.32e-2)" "unprognostic (1.44e-1)" "unprognostic (1.55e-1)" "unprognostic (4.11e-2)" "unprognostic (1.99e-1)" "unprognostic (2.27e-1)" "unprognostic (9.08e-2)" "unprognostic (5.14e-2)" "unprognostic (3.52e-2)" "unprognostic (2.20e-1)" "unprognostic (3.33e-3)" "unprognostic (9.57e-2)" "prognostic favorable (5.69e-9)" "unprognostic (2.28e-1)" "unprognostic (3.21e-2)" "unprognostic (1.62e-2)" "unprognostic (1.57e-1)" 5.1 4.7 5.3 4.8 5.2 1.9 6.3 6.8 10.2 6.3 6.4 4.8 3.4 6.0 7.6 5.0 6.3 3.1 5.5 5.0 6.2 7.3 6.0 4.0 6.5 5.1 5.2 5.7 3.8 8.0 4.2 3.6 5.5 6.2 4.6 7.3 3.9 6.4 4.0 3.8 4.3 5.3 5.2 4.4 4.1 3.9 5.2 7.8 5.7 4.7 9.2 5.2 3.2 5.3 8.8 6.7 15.7 13.7 16.3 5.1 7.7 10.7 12.3 13.2 14.6 10.2 4.0 7.5 20.8 12.0 14.2 20.0 0.0 13.8 10.1 11.6 7.3 13.3 18.3 5.9 9.9 0.0 9.8 7.8 13.0 9.8 9.0 8.9 4.3 16.9 17.1 9.6 16.1 13.4 15.4 6.3 6.8 19.0 5.8 17.8 13.7 7.2 23.4 9.8 21.1 17.6 13.8 11.6 6.0 12.1 14.1 20.2 3.7 15.6 7.1 18.1 17.4 6.5 16.6 3.0 9.7 10.9 16.5 1.7 2.6 3.8 2.3 2.4 3.3 3.2 3.9 2.9 4.4 3.5 6.0 4.1 0.8 2.0 2.2 2.6 3.3 3.2 5.3 5.2 6.8 10.2 5.0 6.2 5.1 5.2 5.5 5.2 5.2 5.3 1.5 0.0 3.1 1.3 3.5 3.1 3.7 1.9 1.8 7.6 2.9 2.8 3.6 5.7 5.7 3.7 8.4 4.3 2.7 2.8 3.9 6.5 2.1 3.6 3.9 3.1 5.4 4.8 1.1 4.0 2.3 3.7 2.0 4.1 1.3 2.2 5.0 4.1 2.7 3.3 1.6 2.2 4.1 1.3 0.8 1.5 5.0 2.7 0.0 1.9 2.4 7.3 4.1 0.5 1.7 3.4 2.1 1.5 2.5 3.3 1.8 4.7 6.2 6.6 6.6 5.1 3.7 23.4 10.5 2.7 2.8 2.5 2.6 2.4 3.3 2.8 LDHB ENSG00000111716 "Lactate dehydrogenase B" P07195 12 21635342-21757857 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1947.7;kidney: 1726.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 2502.3;Cytotrophoblasts: 1693.0;Distal tubular cells: 3306.5;Proximal tubular cells: 3483.9;Syncytiotrophoblasts: 1639.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 6021.8" "CAB004641, HPA019007" Enhanced Supported Cytosol No No 560000000 "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "CAB004641: AB_425525, HPA019007: AB_2670008" "unprognostic (2.93e-1)" "unprognostic (9.20e-3)" "unprognostic (6.10e-2)" "unprognostic (1.11e-1)" "unprognostic (5.39e-3)" "unprognostic (1.36e-3)" "unprognostic (1.61e-2)" "unprognostic (1.72e-2)" "unprognostic (5.34e-2)" "unprognostic (8.40e-2)" "unprognostic (2.91e-1)" "unprognostic (6.41e-2)" "prognostic favorable (2.51e-4)" "unprognostic (1.31e-1)" "unprognostic (1.71e-1)" "unprognostic (2.55e-1)" "unprognostic (9.32e-2)" 549.9 424.8 509.1 259.2 528.2 352.8 321.1 593.7 617.0 238.6 549.8 320.2 84.4 273.1 169.0 166.6 252.9 232.9 1947.7 484.1 581.9 1726.6 70.5 220.4 425.8 564.4 575.4 472.4 370.3 447.3 161.3 298.2 556.2 240.9 277.0 290.0 162.3 287.2 309.4 81.4 171.3 309.7 537.8 182.0 459.1 119.5 582.5 534.5 348.5 950.4 449.4 417.9 171.2 517.8 647.2 1697.3 1457.5 966.0 1021.7 1126.6 1689.4 879.8 873.0 1201.5 1179.4 2712.9 3.6 2268.6 561.5 597.3 1170.1 315.8 2031.4 1631.4 1518.4 586.5 1413.1 2339.5 1619.0 3.0 975.0 2212.8 967.9 1300.5 572.1 1056.8 1423.4 1416.9 1395.2 1610.8 1304.6 332.6 1342.7 3.2 1895.9 2665.6 4216.4 1051.1 727.7 1681.3 2032.0 1838.7 6021.8 2832.7 467.2 1077.8 403.6 618.1 1586.1 3842.2 5.3 1704.6 548.3 803.7 1048.1 578.5 1684.5 291.0 420.9 2953.4 891.8 1037.5 978.2 540.8 201.9 25.1 346.8 124.7 583.1 349.4 1341.5 723.8 367.2 250.9 1722.4 1124.1 31.7 459.0 95.2 427.7 1405.8 1431.2 509.1 528.2 593.7 617.0 484.1 581.9 564.4 575.4 556.2 537.8 582.5 517.8 89.8 141.1 316.4 68.2 242.2 73.0 439.5 1103.1 221.4 151.5 332.4 325.0 2502.3 298.8 433.9 474.5 68.8 1693.0 208.0 69.6 3306.5 18.4 10.5 224.3 325.0 227.3 92.4 361.2 39.4 314.9 870.1 299.4 222.8 309.4 268.6 412.6 155.7 11.2 612.9 141.3 55.6 152.2 956.2 189.8 104.3 34.3 274.6 174.8 179.7 33.7 197.3 277.6 159.6 47.7 40.3 99.7 84.3 415.2 303.1 310.6 0.2 3483.9 363.0 118.1 236.7 195.2 363.7 21.5 124.3 216.3 64.2 1639.5 398.1 1105.3 257.0 344.9 LDHD ENSG00000166816 "Lactate dehydrogenase D" Q86WU2 16 75111860-75116780 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 85.6;liver: 135.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 37.3;Distal enterocytes: 80.2;Distal tubular cells: 37.2;Hepatocytes: 88.6;Proximal tubular cells: 118.1" "Cancer enhanced" "Detected in all" "liver cancer: 32.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 11.1" "Group enriched" "Detected in many" 45 "granulocytes: 11.1;monocytes: 4.8" "Cell line enhanced" "Detected in many" "Hep G2: 11.4;HMC-1: 14.4;T-47d: 29.1;U-266/70: 11.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041766, HPA048639, HPA066148" Enhanced Approved Cytosol No NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA041766: AB_2677660, HPA048639: AB_2680473, HPA066148: AB_2685626" "unprognostic (8.75e-2)" "unprognostic (3.68e-3)" "unprognostic (1.27e-1)" "unprognostic (5.28e-2)" "unprognostic (1.57e-1)" "unprognostic (1.53e-1)" "prognostic favorable (5.61e-4)" "unprognostic (2.49e-3)" "unprognostic (1.91e-1)" "unprognostic (2.72e-1)" "unprognostic (3.74e-1)" "unprognostic (4.01e-1)" "prognostic favorable (2.95e-14)" "unprognostic (4.10e-3)" "unprognostic (4.49e-2)" "unprognostic (7.00e-2)" "unprognostic (2.20e-1)" 24.9 14.4 17.7 2.1 19.7 0.7 11.7 20.5 22.6 5.4 34.1 27.2 8.8 3.5 1.1 10.8 5.5 3.0 85.6 16.1 18.9 36.1 135.5 4.9 0.8 20.8 20.2 16.4 18.7 17.0 11.8 0.7 22.4 8.1 9.7 1.3 21.3 3.2 68.7 5.8 5.7 1.2 17.0 1.1 23.1 1.7 19.3 0.5 10.6 52.7 0.6 2.6 3.7 17.5 0.7 2.1 0.0 0.2 1.6 1.4 6.1 0.2 0.1 0.2 0.2 2.8 2.6 0.1 2.1 0.9 1.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.8 11.4 2.6 0.0 14.4 2.0 0.3 0.0 0.0 0.6 0.1 0.4 0.7 2.5 0.0 5.3 0.1 0.8 1.4 2.7 1.3 0.0 0.0 7.8 1.4 0.1 0.0 0.0 0.2 5.2 0.3 0.7 29.1 3.3 0.0 0.0 0.2 0.0 0.0 11.5 0.6 0.0 1.9 0.1 0.0 11.1 2.2 0.6 0.0 3.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.8 17.7 19.7 20.5 22.6 16.1 18.9 20.8 20.2 22.4 17.0 19.3 17.5 1.6 0.0 6.7 7.8 1.0 0.6 1.8 2.2 0.6 0.5 6.5 2.4 37.3 11.5 2.3 11.0 0.0 2.1 0.1 80.2 37.2 2.3 0.4 2.2 0.3 1.7 3.0 2.7 1.0 6.2 1.2 2.3 32.6 3.8 10.2 2.1 4.2 88.6 7.2 1.7 1.4 11.0 0.0 6.0 1.0 0.6 0.0 3.0 5.4 1.9 2.0 12.0 0.0 1.0 3.2 3.0 28.3 0.0 0.8 2.1 2.4 118.1 2.0 1.4 0.0 4.1 1.3 0.0 0.7 3.6 0.3 3.1 1.0 1.8 15.7 1.5 LGALS12 GRIP1 ENSG00000133317 "Galectin 12" Q96DT0 11 63506052-63516774 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 78.3;breast: 41.3" "Cell type enhanced" "Detected in some" "granulocytes: 17.8;Macrophages: 13.3;monocytes: 2.5;Muller glia cells: 3.9" "Cancer enhanced" "Detected in some" "renal cancer: 1.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 20 "eosinophil: 554.9" "Lineage enriched" "Detected in many" 20 "granulocytes: 554.9" "Group enriched" "Detected in some" 14 "ASC diff: 28.9;HL-60: 53.0;NB-4: 109.4;U-937: 112.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA021124 Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 24: NB-4 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA021124: " "unprognostic (3.89e-2)" "unprognostic (4.40e-2)" "unprognostic (5.17e-2)" "unprognostic (1.79e-1)" "unprognostic (6.26e-2)" "unprognostic (4.75e-2)" "unprognostic (1.51e-1)" "unprognostic (4.31e-2)" "unprognostic (1.01e-1)" "unprognostic (2.13e-3)" "unprognostic (4.69e-2)" "unprognostic (3.08e-1)" "prognostic unfavorable (4.60e-7)" "unprognostic (2.72e-3)" "unprognostic (1.19e-1)" "unprognostic (6.22e-2)" "unprognostic (8.60e-2)" 78.3 0.8 0.1 2.7 0.2 18.4 41.3 0.1 0.2 0.1 0.4 0.9 0.5 0.2 0.0 0.2 1.0 1.7 2.1 0.1 0.2 0.3 0.3 1.0 0.1 0.2 0.2 0.2 0.6 0.0 0.0 0.1 0.2 0.4 0.6 1.9 4.5 0.7 0.5 1.0 2.0 1.0 0.2 1.1 0.9 0.0 0.1 0.3 0.7 1.4 0.0 1.0 0.3 0.2 0.0 0.0 0.0 0.0 28.9 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.8 53.0 3.3 3.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 109.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 5.3 0.0 0.0 0.0 0.0 0.0 2.4 0.2 0.0 0.0 112.2 0.0 15.5 28.1 554.9 0.2 3.3 0.2 0.0 0.0 0.0 7.5 0.1 0.1 0.1 5.7 0.2 0.5 0.7 0.3 17.3 0.1 0.2 0.1 0.2 0.1 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 17.8 0.0 1.1 0.1 1.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 13.3 0.0 0.0 2.5 3.9 0.0 0.5 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 LGALS9 LGALS9A ENSG00000168961 "Galectin 9" O00182 17 27629798-27649560 "Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 99.1;stomach 1: 87.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 181.1;Gastric mucus-secreting cells: 174.8;Hofbauer cells: 298.2;Intestinal goblet cells: 183.5;Kupffer cells: 254.2;Paneth cells: 181.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 40.2;HMC-1: 124.9;MOLT-4: 44.8;REH: 48.4;THP-1: 83.2;U-937: 92.1" "HPA046876, HPA047218" Approved Approved Cytosol "Secreted to blood" NA NA 448000 "Cluster 7: Monocytes - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA046876: AB_2679852, HPA047218: AB_2679988" "unprognostic (2.62e-2)" "prognostic favorable (2.35e-5)" "unprognostic (1.16e-2)" "unprognostic (3.57e-1)" "unprognostic (2.01e-1)" "unprognostic (2.46e-3)" "unprognostic (1.58e-2)" "unprognostic (8.60e-2)" "unprognostic (4.79e-1)" "unprognostic (1.80e-1)" "unprognostic (8.13e-3)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.52e-5)" "unprognostic (4.76e-2)" "unprognostic (3.02e-2)" "unprognostic (2.23e-2)" "unprognostic (2.24e-3)" 20.7 6.4 12.6 46.0 13.0 68.5 9.5 13.8 20.8 25.6 14.3 99.1 46.3 12.8 3.0 14.5 28.4 38.2 8.7 12.8 13.4 2.4 11.6 34.2 60.9 21.7 15.2 5.3 5.2 2.8 1.2 16.8 16.5 3.7 89.2 1.0 21.2 7.9 3.8 4.2 41.8 19.4 17.3 50.7 87.5 3.8 17.0 29.1 4.1 4.1 38.9 39.6 1.9 20.1 2.0 0.7 0.6 0.3 0.1 0.2 1.6 0.4 1.3 8.9 29.6 0.1 12.6 1.5 14.2 1.1 1.5 4.1 0.3 0.1 0.5 9.4 0.9 14.9 0.9 0.0 1.0 40.2 124.9 0.3 0.0 0.4 0.0 0.5 16.5 13.6 0.6 0.5 0.0 0.1 44.8 15.0 0.4 28.4 0.0 48.4 0.0 3.6 5.9 1.0 0.3 0.8 0.0 4.4 0.2 0.9 0.2 83.2 3.1 0.0 0.3 0.1 0.2 0.1 0.1 0.3 0.2 92.1 0.2 32.6 116.2 78.2 5.6 214.9 2.6 32.3 15.6 5.9 165.5 41.7 9.6 4.0 41.7 22.0 217.4 28.5 40.3 75.1 12.6 13.0 13.8 20.8 12.8 13.4 21.7 15.2 16.5 17.3 17.0 20.1 32.2 9.6 6.3 2.0 42.2 3.2 7.7 32.9 18.8 0.2 10.5 13.2 1.7 20.0 40.5 7.3 0.0 2.3 19.0 181.1 3.9 124.1 1.5 11.4 11.6 43.5 40.5 64.3 0.4 126.9 3.1 7.4 174.8 12.9 31.1 11.2 26.0 2.2 298.2 0.0 0.6 183.5 26.4 254.2 85.4 2.2 4.4 154.1 1.8 25.3 150.7 0.2 41.2 3.5 0.9 146.0 181.6 3.0 3.5 4.4 20.6 1.4 15.4 0.6 19.7 1.6 6.2 0.1 0.7 8.8 1.7 3.7 19.6 86.2 126.7 31.1 LGALS9B ENSG00000170298 "Galectin 9B" Q3B8N2 17 20449395-20467539 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 15.4;intestine: 11.1;stomach 1: 30.9" "Cell type enhanced" "Detected in some" "Distal enterocytes: 17.7;Gastric mucus-secreting cells: 109.1;Intestinal goblet cells: 32.6;NK-cells: 28.8;Paneth cells: 42.3" "Cancer enhanced" "Detected in some" "stomach cancer: 1.3" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 17 "NK-cell: 12.7" "Lineage enriched" "Detected in single" 17 "NK-cells: 12.7" "Group enriched" "Detected in some" 7 "CAPAN-2: 8.5;U-937: 2.8" "HPA046876, HPA047218" Approved Uncertain Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol "HPA046876: AB_2679852, HPA047218: AB_2679988" "unprognostic (4.69e-2)" "unprognostic (1.11e-2)" "unprognostic (2.67e-2)" "unprognostic (4.05e-1)" "unprognostic (8.62e-2)" "unprognostic (1.94e-1)" "unprognostic (3.93e-3)" "unprognostic (2.72e-1)" "unprognostic (2.26e-2)" "unprognostic (6.85e-2)" "unprognostic (1.32e-2)" "unprognostic (3.20e-1)" "unprognostic (3.79e-2)" "unprognostic (1.38e-2)" "unprognostic (1.92e-1)" "unprognostic (5.27e-2)" "unprognostic (1.05e-1)" 0.0 0.0 0.0 0.5 0.0 1.8 0.0 0.0 0.0 1.6 0.0 8.2 3.3 0.0 0.0 15.4 0.0 7.4 0.0 0.1 0.0 0.0 0.1 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 11.1 0.0 2.2 0.0 0.0 0.6 3.4 0.3 0.0 0.6 30.9 0.1 0.0 0.0 0.0 0.0 1.7 0.0 4.3 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.1 0.0 0.7 0.2 0.0 0.2 0.1 0.0 0.3 0.2 0.1 0.3 0.1 12.7 0.3 0.1 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.3 2.3 0.3 1.1 0.6 0.0 0.0 0.0 0.1 1.5 2.2 0.0 0.0 0.0 9.9 17.7 0.0 0.2 0.0 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 109.1 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 32.6 2.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.1 0.0 28.8 0.0 0.0 0.6 42.3 0.0 1.2 0.2 7.7 0.0 2.5 0.0 0.0 0.0 0.2 0.0 0.0 3.7 0.0 0.0 2.1 0.0 6.6 0.3 LGALS9C ENSG00000171916 "Galectin 9C" Q6DKI2 17 18476737-18494945 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 10.3;intestine: 9.3;stomach 1: 11.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 48.1;Gastric mucus-secreting cells: 194.2;Intestinal goblet cells: 37.9;Paneth cells: 58.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "neutrophil: 1.9;NK-cell: 5.5" "Group enriched" "Detected in many" 6 "granulocytes: 1.9;NK-cells: 5.5" "Not detected" "Not detected" "HPA046876, HPA047218" Approved Approved Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol "HPA046876: AB_2679852, HPA047218: AB_2679988" "unprognostic (4.47e-2)" "unprognostic (1.43e-3)" "unprognostic (3.17e-2)" "unprognostic (4.30e-2)" "unprognostic (5.92e-1)" "unprognostic (3.02e-2)" "unprognostic (2.52e-1)" "unprognostic (5.16e-2)" "unprognostic (1.63e-1)" "unprognostic (2.56e-1)" "unprognostic (1.23e-1)" "unprognostic (1.12e-1)" "unprognostic (2.34e-2)" "unprognostic (1.04e-2)" "unprognostic (5.85e-2)" "unprognostic (4.27e-3)" "unprognostic (9.84e-2)" 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 0.0 9.3 1.1 0.0 0.0 10.3 0.0 3.1 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.7 0.0 1.6 0.0 0.0 0.2 4.3 0.0 0.0 1.4 11.5 0.1 0.0 0.0 0.0 0.0 0.3 0.0 2.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.3 0.4 0.5 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.1 1.9 5.5 0.6 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.4 0.6 0.0 0.1 0.0 0.2 0.0 0.6 0.0 0.0 0.1 3.4 48.1 0.0 0.2 0.0 0.0 0.0 0.1 7.8 0.0 0.0 0.0 0.0 0.0 194.2 0.1 0.0 0.0 0.4 0.1 0.7 0.0 0.0 37.9 4.1 2.2 0.0 0.0 0.0 1.3 0.0 0.0 0.5 0.0 9.2 0.0 0.0 0.4 58.4 0.0 0.2 0.0 13.5 0.0 2.7 0.0 0.0 0.0 0.1 0.0 0.1 4.5 0.1 0.0 1.8 0.0 10.8 0.2 LGI3 ENSG00000168481 "Leucine rich repeat LGI family member 3" Q8N145 8 22146830-22157084 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 112.6" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 22.2;Excitatory neurons: 17.7;Inhibitory neurons: 23.7;Melanocytes: 40.9;Oligodendrocytes: 58.4" "Group enriched" "Detected in many" 5 "glioma: 4.7;melanoma: 14.3;thyroid cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.1;SCLC-21H: 1.6;SK-MEL-30: 1.6;WM-115: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024826 Approved Cytosol "Secreted in brain" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA024826: AB_10601131" "unprognostic (4.41e-2)" "unprognostic (1.78e-1)" "unprognostic (3.28e-1)" "unprognostic (8.11e-3)" "unprognostic (1.14e-1)" "unprognostic (7.45e-2)" "unprognostic (3.38e-1)" "unprognostic (2.43e-2)" "unprognostic (9.64e-2)" "unprognostic (1.64e-2)" "unprognostic (6.25e-3)" "unprognostic (1.26e-2)" "unprognostic (5.59e-5)" "unprognostic (1.36e-2)" "unprognostic (9.41e-2)" "unprognostic (4.80e-2)" "unprognostic (4.14e-2)" 0.3 3.4 44.2 0.1 79.7 0.1 0.2 81.1 84.6 2.9 5.2 0.8 0.3 1.2 0.3 6.5 1.6 0.1 2.2 43.4 70.4 0.4 0.1 15.9 0.0 85.8 72.4 0.2 0.8 0.3 2.8 0.0 90.7 1.3 0.1 3.9 1.7 2.8 0.2 15.0 0.5 0.6 57.1 0.1 0.9 0.8 86.3 0.3 13.0 0.1 0.3 0.2 2.5 112.6 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.3 0.2 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 1.6 0.2 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.2 79.7 81.1 84.6 43.4 70.4 85.8 72.4 90.7 57.1 86.3 112.6 0.0 0.0 22.2 2.0 0.0 2.3 0.0 0.0 0.0 2.7 0.1 0.0 4.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 1.8 0.0 17.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.7 0.0 0.0 0.0 0.4 0.0 0.3 0.1 40.9 2.8 0.0 1.2 0.0 6.6 58.4 0.1 0.0 7.2 0.0 0.0 0.0 0.8 0.0 2.9 0.0 0.0 0.6 0.1 0.1 1.4 0.6 0.0 0.0 0.9 0.0 0.0 LHB "CGB4, hLHB, LSH-B" ENSG00000104826 "Luteinizing hormone subunit beta" P01229 19 49015980-49017091 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 248 "pituitary gland: 4493.5" "Cell type enhanced" "Detected in some" "Early spermatids: 3.7;Late spermatids: 4.1;Pancreatic endocrine cells: 8.2;Syncytiotrophoblasts: 10.3" "Cancer enhanced" "Detected in many" "melanoma: 2.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.7;HEK 293: 1.5;Hep G2: 1.4;K-562: 1.3;U-266/84: 2.0" "CAB022241, CAB022707, HPA038925" Enhanced Approved Cytosol "Secreted to blood" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "CAB022241: , CAB022707: , HPA038925: AB_2676272" "unprognostic (8.12e-2)" "unprognostic (3.59e-1)" "unprognostic (2.34e-3)" "unprognostic (1.41e-2)" "unprognostic (8.89e-2)" "unprognostic (6.25e-2)" "unprognostic (3.90e-3)" "unprognostic (5.69e-2)" "unprognostic (7.04e-2)" "unprognostic (6.06e-2)" "prognostic unfavorable (6.78e-4)" "unprognostic (2.47e-2)" "unprognostic (1.68e-3)" "unprognostic (1.38e-1)" "unprognostic (4.46e-1)" "unprognostic (9.52e-2)" "unprognostic (4.86e-2)" 1.0 5.1 0.2 0.0 0.1 0.0 0.6 0.4 0.3 0.5 0.0 0.5 1.3 0.5 0.0 1.3 0.6 0.0 0.9 0.1 0.2 1.4 1.9 0.9 0.2 0.2 0.1 0.6 18.0 0.6 4493.5 0.0 0.2 0.9 0.0 0.0 1.1 0.0 0.5 3.1 1.5 0.0 0.0 1.2 4.5 5.0 0.1 0.0 0.8 0.0 0.0 0.3 0.6 0.3 0.1 2.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.1 0.0 0.9 0.7 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 1.5 0.0 0.0 1.4 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 1.3 0.3 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.7 0.4 0.4 0.0 0.6 1.2 0.6 0.5 0.0 0.6 0.0 0.5 0.0 0.0 0.9 0.6 0.0 0.1 0.1 2.0 0.3 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.4 0.3 0.1 0.2 0.2 0.1 0.2 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.8 0.3 0.5 0.0 0.0 0.1 0.3 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.9 0.0 3.7 0.3 0.0 0.2 0.0 0.0 0.0 0.9 1.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 4.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.1 1.4 0.1 0.2 0.0 0.0 0.0 0.2 1.1 1.6 0.0 0.0 10.3 0.1 0.1 0.1 0.1 LIF "CDF, DIA, HILDA" ENSG00000128342 "LIF interleukin 6 family cytokine" P15018 22 30240453-30246759 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 47.7;urinary bladder: 91.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 95.5;Club cells: 56.3;Endometrial ciliated cells: 71.7;Fibroblasts: 51.9;Glandular and luminal cells: 192.9;granulocytes: 67.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 88.3;hTEC/SVTERT24-B: 113.0;hTERT-RPE1: 104.4;U-138 MG: 123.9;U-251 MG: 94.5;U-87 MG: 97.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018844, CAB025985" Uncertain Supported Cytosol "Secreted in other tissues" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 44: Endometrium - Transcription" Cytosol "CAB025985: , HPA018844: AB_1852814" "unprognostic (1.28e-2)" "prognostic unfavorable (9.01e-4)" "unprognostic (8.79e-2)" "unprognostic (4.61e-2)" "unprognostic (7.36e-3)" "unprognostic (4.18e-3)" "unprognostic (1.17e-2)" "unprognostic (1.41e-2)" "unprognostic (3.18e-3)" "unprognostic (1.22e-1)" "unprognostic (8.10e-2)" "unprognostic (9.65e-2)" "prognostic unfavorable (6.78e-8)" "unprognostic (2.02e-1)" "unprognostic (6.40e-2)" "unprognostic (8.99e-2)" "unprognostic (4.71e-3)" 37.9 4.3 0.6 22.4 0.7 1.6 4.7 0.6 1.7 6.8 6.6 7.5 6.7 11.7 0.6 3.1 9.8 47.7 18.4 0.9 0.8 14.2 5.0 29.9 4.3 1.2 1.3 2.3 13.4 0.4 10.4 2.7 0.9 12.0 8.0 3.0 4.9 2.1 0.8 10.7 9.3 8.3 1.1 1.5 7.8 0.6 2.6 1.3 5.4 1.0 1.7 91.0 2.4 1.1 29.0 47.9 1.3 10.6 0.0 3.9 17.1 4.1 17.2 5.1 12.1 7.7 47.3 0.0 10.1 0.2 88.3 7.3 1.1 13.1 6.9 6.8 2.1 3.7 19.7 10.9 4.5 0.1 36.7 4.3 2.5 113.0 3.3 104.4 0.0 0.2 0.8 0.1 22.6 21.5 0.6 0.1 1.8 27.0 29.5 0.9 15.9 0.0 40.7 11.0 0.2 0.6 4.9 0.4 8.8 5.0 1.0 0.5 0.3 123.9 45.3 47.3 94.5 0.0 0.2 0.1 97.4 0.1 58.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.7 0.6 1.7 0.9 0.8 1.2 1.3 0.9 1.1 2.6 1.1 0.6 22.4 44.2 0.3 0.0 3.4 14.0 95.5 0.0 0.1 40.0 10.9 0.2 10.0 56.3 5.5 0.0 0.2 2.9 3.9 0.0 39.6 0.3 71.7 16.2 3.6 0.0 0.0 0.0 3.4 0.7 51.9 0.5 192.9 67.0 0.2 0.0 0.0 1.1 0.0 0.0 3.5 10.2 0.6 3.2 0.0 0.0 3.9 0.0 0.0 0.0 1.7 0.0 0.0 0.0 40.3 3.8 0.0 0.4 15.7 5.3 1.0 15.6 0.2 0.0 17.7 30.2 0.1 0.2 1.5 2.8 0.3 5.5 0.1 7.1 20.3 LIPE HSL ENSG00000079435 "Lipase E, hormone sensitive type" Q05469 19 42401514-42427388 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid degradation, Lipid metabolism, Steroid metabolism, Sterol metabolism" Hydrolase "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adipose tissue: 834.5;breast: 524.7" "Cell type enhanced" "Detected in many" "Adipocytes: 76.1;Early spermatids: 127.8;Late spermatids: 236.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 7 "ASC diff: 136.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006567, CAB017700" Enhanced Supported Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB017700: AB_2135504, HPA006567: AB_2667618" "unprognostic (4.24e-2)" "unprognostic (2.46e-2)" "unprognostic (8.99e-3)" "unprognostic (3.74e-2)" "unprognostic (1.77e-1)" "unprognostic (3.38e-3)" "unprognostic (5.68e-2)" "unprognostic (2.84e-1)" "unprognostic (3.11e-1)" "unprognostic (9.44e-2)" "prognostic favorable (1.15e-4)" "unprognostic (1.52e-1)" "unprognostic (3.63e-10)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (3.76e-2)" "unprognostic (2.34e-3)" 834.5 45.1 22.7 7.7 71.7 5.0 524.7 77.2 41.5 5.1 0.6 10.9 5.3 6.4 1.2 8.6 5.8 3.7 32.5 23.8 42.6 7.7 1.5 3.7 7.3 100.3 73.9 4.9 6.2 4.7 6.9 2.9 90.0 7.1 1.4 2.0 17.2 2.6 19.7 23.6 24.4 2.6 44.0 14.4 8.5 68.6 57.1 6.9 9.6 23.3 3.7 14.2 7.7 116.9 12.7 9.6 6.0 2.3 136.8 1.3 0.1 5.8 3.1 9.2 8.5 2.3 4.6 20.6 6.3 1.8 4.5 5.6 3.7 11.5 1.0 4.0 6.1 5.8 5.3 0.2 2.7 0.1 13.9 1.2 10.7 1.5 2.1 1.3 2.6 8.5 2.7 12.8 1.2 0.1 14.8 0.5 0.8 9.7 2.7 12.2 1.1 6.9 2.6 13.1 8.5 8.8 5.1 5.7 5.6 0.3 1.5 7.5 4.7 2.5 7.8 1.1 5.3 9.7 8.5 15.6 6.3 0.7 8.7 11.0 8.6 3.8 2.5 4.7 2.3 3.4 3.2 3.7 3.6 4.5 2.8 2.5 1.5 3.6 2.7 2.9 3.0 3.1 22.7 71.7 77.2 41.5 23.8 42.6 100.3 73.9 90.0 44.0 57.1 116.9 76.1 0.0 3.3 4.2 8.1 4.1 12.1 2.4 4.6 11.0 4.8 2.9 2.5 0.0 2.0 1.8 10.4 0.1 4.8 1.3 1.9 8.0 127.8 0.9 3.4 10.2 0.0 5.3 4.6 2.7 0.1 2.0 3.6 1.5 0.0 6.6 17.9 0.0 0.6 8.4 6.7 2.0 6.1 2.2 2.4 236.5 3.1 0.8 5.4 4.7 0.9 4.0 6.2 6.0 37.9 1.8 0.7 1.5 3.0 6.7 18.4 1.5 0.8 13.9 0.0 7.2 2.1 39.4 13.1 2.5 2.4 0.0 5.1 5.2 2.9 10.7 LIX1L MGC46719 ENSG00000271601 "Limb and CNS expressed 1 like" Q8IVB5 1 145933423-145958017 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063598 Approved Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA063598: AB_2685055" "unprognostic (5.21e-2)" "unprognostic (4.09e-1)" "unprognostic (6.84e-3)" "unprognostic (2.85e-2)" "unprognostic (3.71e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.61e-4)" "unprognostic (9.81e-2)" "unprognostic (3.46e-1)" "unprognostic (3.87e-2)" "unprognostic (1.84e-3)" "unprognostic (3.51e-2)" "prognostic unfavorable (3.19e-5)" "unprognostic (2.10e-3)" "unprognostic (4.95e-1)" "unprognostic (1.25e-2)" "prognostic unfavorable (5.27e-4)" 21.0 19.0 14.6 15.2 15.1 6.4 16.0 13.8 13.1 27.1 15.6 23.0 6.7 27.6 11.1 9.8 21.1 15.6 16.3 12.9 13.5 9.8 10.2 15.6 20.4 15.0 15.2 36.9 5.8 7.5 16.3 16.2 14.0 16.2 9.2 19.0 9.4 20.8 34.8 8.1 13.3 25.7 13.9 20.8 11.3 6.6 15.8 16.6 10.8 31.5 20.8 21.1 16.9 15.0 7.3 10.3 31.0 34.5 63.4 53.5 0.4 16.3 29.4 24.8 18.1 0.8 6.7 19.6 17.5 33.1 9.3 0.4 14.6 13.6 23.3 18.2 4.5 10.9 11.0 10.4 20.8 26.2 24.8 32.9 6.2 20.3 29.3 39.9 48.7 25.8 16.4 30.6 39.9 0.2 34.6 21.8 9.0 0.1 13.2 23.2 15.6 32.4 25.7 0.2 11.1 31.6 33.5 0.1 24.9 12.8 1.2 20.3 38.0 41.9 11.5 27.6 27.8 24.5 18.7 19.9 29.5 21.4 20.7 4.0 2.2 3.9 5.7 2.2 7.0 3.0 6.6 5.8 2.1 3.1 6.1 8.0 3.7 3.8 3.8 3.3 5.4 2.6 14.6 15.1 13.8 13.1 12.9 13.5 15.0 15.2 14.0 13.9 15.8 15.0 29.7 0.0 5.8 11.1 23.1 11.3 10.6 10.8 11.4 17.1 3.8 7.5 17.5 14.3 4.9 11.0 8.4 1.4 18.6 2.8 3.9 9.6 10.4 2.3 21.6 36.7 12.6 23.5 5.1 10.0 4.3 28.4 2.6 3.5 5.1 10.8 45.7 19.6 21.1 13.5 6.1 1.4 8.2 24.3 43.8 3.6 35.8 18.8 28.4 15.9 27.4 28.1 35.0 8.5 7.0 11.0 1.2 56.4 17.8 7.5 0.1 7.7 3.0 13.6 26.3 16.8 37.9 24.1 4.7 3.1 7.7 0.8 37.4 21.4 2.1 4.2 LMBR1 "ACHP, C7orf2, FLJ11665, ZRS" ENSG00000105983 "Limb development membrane protein 1" Q8WVP7 7 156668946-156893216 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 110.7;Inhibitory neurons: 128.7;Microglial cells: 99.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016592 Approved Approved Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 18: U-2197 - ECM organization" "Cluster 59: Non-specific - Transcription" Cytosol "HPA016592: AB_1852943" "unprognostic (8.81e-3)" "unprognostic (1.73e-2)" "unprognostic (9.49e-2)" "unprognostic (2.02e-1)" "unprognostic (3.77e-3)" "unprognostic (6.90e-2)" "unprognostic (1.30e-2)" "unprognostic (3.28e-1)" "unprognostic (1.21e-2)" "unprognostic (1.12e-2)" "unprognostic (1.69e-1)" "unprognostic (1.02e-1)" "prognostic favorable (1.44e-6)" "unprognostic (3.35e-1)" "unprognostic (3.93e-2)" "unprognostic (1.48e-1)" "unprognostic (7.10e-2)" 10.0 26.0 8.8 8.4 10.4 7.8 10.7 11.3 13.2 13.6 7.8 8.9 8.0 13.2 18.1 9.9 14.1 10.2 11.2 9.7 13.2 15.7 13.8 9.1 9.4 11.0 10.0 16.5 8.8 38.0 7.5 10.1 11.2 12.2 10.3 14.3 8.4 10.7 6.7 8.4 9.3 13.2 8.9 7.6 11.9 17.7 10.6 11.8 17.6 11.4 8.7 11.9 6.0 8.5 26.9 20.6 27.5 33.4 21.1 24.0 16.6 14.5 20.5 14.2 16.8 15.4 42.4 25.3 27.6 19.7 27.3 20.4 28.4 28.9 29.1 19.5 25.5 19.1 11.6 19.7 13.6 23.8 13.6 19.3 27.0 20.4 27.3 22.8 29.6 23.4 35.7 23.8 26.9 24.3 25.1 20.5 29.4 30.4 18.7 13.1 18.1 31.6 22.8 25.1 26.1 51.9 20.4 27.8 15.6 17.8 19.1 14.3 38.4 25.1 9.3 82.7 19.6 25.6 22.6 24.0 40.0 30.2 16.4 1.8 0.7 1.0 0.7 0.4 1.4 0.6 1.2 1.2 1.3 0.8 1.5 1.0 0.6 0.2 0.7 0.9 0.9 0.6 8.8 10.4 11.3 13.2 9.7 13.2 11.0 10.0 11.2 8.9 10.6 8.5 25.6 3.2 8.1 54.5 23.7 10.5 13.7 9.9 43.3 11.5 12.8 8.5 17.1 11.5 7.2 12.9 2.1 14.3 8.4 8.6 5.9 11.0 7.4 17.0 8.6 24.8 8.3 17.4 110.7 10.1 5.6 15.2 23.0 15.7 5.7 43.2 9.3 19.2 10.2 8.4 128.7 9.9 10.2 10.1 8.0 9.7 10.5 9.3 7.2 99.3 8.2 6.7 3.1 72.4 70.4 12.6 6.1 8.6 23.4 20.0 9.7 12.2 9.7 10.9 0.0 11.9 11.0 18.0 28.7 30.9 12.8 23.1 18.0 26.2 11.1 16.6 LMOD1 "1D, 64kD, D1" ENSG00000163431 "Leiomodin 1" P29536 1 201896456-201946588 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 513.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 135.5;Leydig cells: 125.6;Peritubular cells: 275.3;Rod photoreceptor cells: 70.2;Sertoli cells: 197.2;Smooth muscle cells: 224.3" "Cancer enhanced" "Detected in all" "prostate cancer: 43.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 15.8;BJ: 21.3;BJ hTERT+: 34.4;fHDF/TERT166: 17.4;HSkMC: 14.5;hTERT-RPE1: 54.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA028325, HPA028435, HPA030097" Enhanced Approved Cytosol No No "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA028325: AB_10600300, HPA028435: AB_10602180, HPA030097: AB_10601223" "unprognostic (3.84e-2)" "unprognostic (5.01e-2)" "unprognostic (1.44e-2)" "unprognostic (1.27e-1)" "unprognostic (5.64e-1)" "unprognostic (6.35e-2)" "prognostic favorable (2.52e-5)" "unprognostic (1.27e-1)" "unprognostic (6.10e-2)" "unprognostic (1.73e-2)" "unprognostic (3.51e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (1.05e-4)" "unprognostic (4.30e-2)" "unprognostic (2.72e-1)" "unprognostic (4.44e-3)" "unprognostic (1.15e-2)" 157.7 52.5 7.8 28.5 9.7 0.0 75.4 5.7 9.1 161.9 5.5 513.9 25.1 309.5 49.7 135.8 194.7 85.5 31.7 6.2 8.0 11.8 5.1 44.3 7.3 13.6 6.5 72.2 8.4 18.2 5.8 35.3 6.8 165.2 46.9 48.0 21.2 242.5 137.5 43.2 115.5 206.6 5.4 18.5 218.6 17.9 9.1 2.5 39.8 45.7 1.6 368.7 111.9 7.2 0.0 0.1 0.4 1.2 15.8 2.0 1.3 21.3 34.4 1.3 1.5 0.1 0.2 0.0 0.7 17.4 0.2 0.3 0.5 0.0 0.4 0.0 1.4 0.0 0.1 0.0 1.5 0.1 0.1 14.5 0.0 1.0 0.0 54.4 0.1 0.0 0.2 0.2 0.7 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.5 0.1 0.4 0.1 0.3 0.0 0.5 0.4 9.5 0.7 0.0 0.0 0.1 0.8 0.3 0.0 0.7 0.6 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 9.7 5.7 9.1 6.2 8.0 13.6 6.5 6.8 5.4 9.1 7.2 16.1 0.0 1.1 8.5 0.3 1.3 1.0 0.3 0.0 4.8 1.6 40.8 25.1 0.0 0.0 0.0 135.5 1.7 0.0 0.1 0.0 0.0 2.1 2.6 64.5 5.8 0.0 0.0 0.5 0.6 0.3 20.4 0.5 1.2 0.0 0.7 9.3 0.4 1.0 3.3 1.0 0.0 0.0 0.0 2.3 8.2 125.6 0.9 3.6 3.7 0.0 7.3 0.0 4.0 1.0 0.0 0.0 275.3 0.0 0.9 0.0 0.1 0.9 70.2 197.2 5.2 224.3 1.2 0.5 0.8 2.3 1.2 1.3 2.1 0.0 0.4 LPIN3 "LIPN3L, SMP2" ENSG00000132793 "Lipin 3" Q9BQK8 20 41340821-41360582 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 214.9;Proximal enterocytes: 76.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 2.3" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" "HPA051466, HPA052667, HPA070640" Approved Supported Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA051466: , HPA052667: AB_2681908, HPA070640: AB_2686288" "unprognostic (2.31e-1)" "unprognostic (4.73e-2)" "unprognostic (1.68e-1)" "prognostic unfavorable (9.74e-4)" "unprognostic (1.88e-1)" "unprognostic (1.04e-1)" "unprognostic (6.91e-3)" "unprognostic (4.26e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (1.74e-4)" "unprognostic (4.29e-2)" "unprognostic (7.79e-2)" "prognostic unfavorable (1.14e-5)" "unprognostic (5.60e-3)" "unprognostic (2.02e-1)" "unprognostic (1.35e-1)" "unprognostic (3.37e-3)" 19.1 7.3 5.6 3.7 5.4 0.3 18.0 4.6 6.8 19.4 8.4 24.0 41.6 14.1 13.1 32.2 17.7 5.8 17.9 5.6 5.2 31.5 30.0 9.1 2.1 6.1 5.2 14.5 15.1 10.3 12.6 3.6 5.4 19.7 13.2 1.3 16.9 9.6 3.3 40.6 32.4 5.9 5.3 5.7 12.3 3.3 6.2 2.0 26.9 2.5 3.2 13.3 26.2 6.1 12.4 12.0 0.7 7.1 18.6 28.8 9.1 7.5 10.3 9.0 12.1 22.3 10.7 0.6 9.1 16.7 9.5 30.6 3.6 19.6 5.6 0.3 6.9 0.6 19.8 11.5 3.0 0.0 8.1 20.8 24.3 15.3 5.9 10.4 2.3 0.3 3.2 0.4 11.3 26.5 0.1 0.3 1.0 7.6 12.1 0.1 0.2 0.9 30.9 15.5 0.9 0.2 10.0 12.6 6.4 5.6 14.8 6.2 0.7 0.6 2.9 10.1 0.1 5.8 3.3 0.1 0.2 0.1 0.6 0.8 0.1 0.2 0.1 0.1 0.2 0.2 0.2 0.1 0.1 0.3 0.2 0.2 0.6 2.3 0.3 0.2 0.1 0.1 5.6 5.4 4.6 6.8 5.6 5.2 6.1 5.2 5.4 5.3 6.2 6.1 7.2 6.4 12.3 12.1 0.8 14.4 8.2 10.0 3.4 0.0 12.7 11.3 0.8 10.0 6.0 11.0 0.0 2.8 0.2 44.4 5.9 8.7 21.6 10.0 12.5 3.2 14.9 2.7 1.0 3.8 3.5 9.4 19.9 33.1 1.3 16.2 5.0 44.1 3.3 0.0 0.3 21.9 4.1 2.2 6.0 214.9 3.1 1.0 10.6 8.4 0.0 5.2 0.0 1.0 0.2 6.4 28.4 2.6 0.1 3.8 76.9 11.8 4.2 0.5 32.9 8.8 8.2 1.0 2.7 4.7 12.6 2.6 1.0 5.2 23.2 4.8 LRCH3 MGC4126 ENSG00000186001 "Leucine rich repeats and calponin homology domain containing 3" Q96II8 3 197791226-197888436 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 102.1;Oligodendrocytes: 139.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 38.9" "Lineage enriched" "Detected in all" 4 "granulocytes: 38.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012380, HPA017299" Uncertain Enhanced Cytosol "Intracellular and membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 52: Non-specific - Transcription" Cytosol "HPA012380: AB_1853260, HPA017299: AB_2669576" "unprognostic (1.25e-1)" "unprognostic (4.92e-1)" "unprognostic (1.43e-1)" "unprognostic (2.69e-3)" "unprognostic (1.05e-1)" "unprognostic (8.26e-2)" "prognostic unfavorable (2.95e-4)" "unprognostic (3.29e-1)" "unprognostic (4.13e-1)" "unprognostic (9.85e-2)" "unprognostic (1.64e-1)" "unprognostic (2.06e-2)" "unprognostic (1.79e-3)" "unprognostic (3.29e-2)" "unprognostic (2.67e-1)" "unprognostic (5.59e-2)" "unprognostic (1.32e-1)" 13.1 10.2 7.7 12.0 11.9 8.0 11.4 18.7 9.1 16.2 7.3 16.3 7.0 15.5 7.7 10.7 13.7 10.2 14.6 7.7 12.5 8.2 10.3 11.9 17.0 9.8 8.1 18.8 9.5 12.2 12.3 10.1 8.5 13.9 10.2 19.2 12.0 12.1 19.3 10.8 12.8 14.8 6.0 13.9 11.2 13.1 10.1 15.5 9.7 11.5 18.7 14.8 13.8 15.7 30.5 10.0 28.8 17.5 28.9 35.2 11.0 21.5 25.6 25.3 31.5 26.0 15.5 16.1 33.5 24.9 40.7 19.1 25.7 21.2 34.5 13.3 14.4 29.8 16.2 19.2 18.9 21.4 19.3 25.0 10.9 24.7 31.9 23.0 30.7 14.7 18.1 27.5 23.4 25.1 15.9 7.8 19.3 15.8 22.3 16.0 17.6 10.6 11.3 19.4 14.2 14.4 28.5 18.5 20.1 26.4 39.0 17.1 30.1 19.4 12.0 24.4 22.2 24.5 26.9 15.2 19.8 28.0 20.3 38.9 4.7 10.1 7.4 6.9 6.0 9.3 5.8 6.3 4.1 6.6 5.3 7.5 2.3 7.1 6.9 3.5 6.1 5.4 7.7 11.9 18.7 9.1 7.7 12.5 9.8 8.1 8.5 6.0 10.1 15.7 19.2 32.1 27.0 64.6 29.7 10.6 18.1 11.4 8.0 56.0 11.6 8.5 15.4 14.3 17.0 9.2 56.3 8.5 25.8 10.4 1.9 10.1 12.8 12.2 22.9 20.8 6.0 11.1 69.8 9.9 6.6 23.8 10.7 16.4 11.4 23.0 34.6 14.2 9.0 38.7 86.1 11.0 8.2 17.6 17.9 9.6 25.1 14.6 17.8 66.5 30.8 19.8 27.8 102.1 139.2 14.1 9.5 28.6 15.1 15.9 7.1 5.2 15.1 43.1 19.7 31.7 22.8 18.0 17.2 9.4 10.5 6.0 19.9 17.0 11.0 14.7 LRIG1 "DKFZP586O1624, LIG-1, LIG1" ENSG00000144749 "Leucine rich repeats and immunoglobulin like domains 1" Q96JA1 3 66378797-66501263 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 144.4" "Cell type enriched" "Detected in many" 5 "Astrocytes: 331.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.1" "Lineage enhanced" "Detected in single" "T-cells: 1.1" "Cell line enhanced" "Detected in many" "Daudi: 79.7;hTEC/SVTERT24-B: 55.2;U-698: 59.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011846 Approved Approved Cytosol NA NA 78000 "Cluster 35: T-regs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol "HPA011846: AB_2668545" "unprognostic (6.41e-2)" "unprognostic (4.18e-2)" "unprognostic (4.35e-3)" "unprognostic (4.58e-2)" "unprognostic (2.12e-2)" "unprognostic (2.28e-1)" "unprognostic (2.32e-1)" "prognostic favorable (3.01e-5)" "unprognostic (5.12e-1)" "unprognostic (7.86e-2)" "unprognostic (2.62e-1)" "unprognostic (2.18e-1)" "unprognostic (2.12e-1)" "unprognostic (8.79e-2)" "unprognostic (1.30e-1)" "unprognostic (1.21e-2)" "prognostic unfavorable (1.50e-4)" 31.0 1.8 33.1 17.0 29.2 4.0 27.2 15.1 21.0 29.9 0.0 38.6 16.8 21.9 3.0 13.5 26.7 20.9 37.0 21.4 26.7 3.6 11.2 17.6 7.9 29.4 39.2 17.1 144.4 5.2 6.5 4.7 17.2 24.8 14.7 5.0 19.2 7.2 37.2 11.7 13.4 30.5 14.3 3.9 36.5 12.5 51.0 3.5 16.2 32.9 9.6 5.9 5.2 17.7 1.4 1.3 27.6 0.5 7.6 4.8 2.8 4.9 26.6 4.6 14.0 23.6 0.3 79.7 13.1 2.2 6.1 0.0 5.5 10.0 10.1 0.0 16.8 0.0 4.1 2.0 1.8 0.7 16.7 6.0 5.4 55.2 9.0 18.8 24.3 0.3 0.3 0.0 1.0 3.6 0.0 0.1 22.8 2.3 0.0 14.1 8.7 3.7 5.1 0.0 3.9 1.0 4.6 4.1 0.2 4.6 25.6 6.7 8.2 13.9 6.3 27.9 12.9 6.2 3.2 59.5 24.3 0.0 5.0 0.0 0.0 0.3 0.1 0.0 0.6 0.1 0.4 0.4 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 1.1 0.1 33.1 29.2 15.1 21.0 21.4 26.7 29.4 39.2 17.2 14.3 51.0 17.7 12.5 38.5 50.2 331.1 4.3 11.3 7.8 8.0 14.2 2.1 51.9 35.8 32.0 11.5 25.0 0.0 8.4 0.2 5.8 9.6 1.9 5.6 1.6 29.1 9.7 9.2 26.5 0.0 10.6 17.1 0.1 17.1 19.9 58.8 1.3 14.9 6.4 20.7 2.0 8.4 15.6 26.2 12.2 1.9 7.7 2.1 11.5 2.4 10.6 57.1 1.7 39.8 0.0 37.7 58.3 6.0 10.2 17.3 8.7 15.6 5.7 1.2 33.7 6.8 0.0 65.5 19.9 1.6 20.0 8.9 11.5 0.1 15.2 2.1 22.8 5.0 LRIG3 "FLJ90440, KIAA3016" ENSG00000139263 "Leucine rich repeats and immunoglobulin like domains 3" Q6UXM1 12 58872149-58920504 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 42.8;Basal squamous epithelial cells: 44.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 49.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010773 Approved Approved Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA010773: AB_1853275" "unprognostic (1.79e-1)" "unprognostic (2.71e-1)" "unprognostic (1.01e-2)" "unprognostic (3.88e-2)" "unprognostic (2.53e-1)" "unprognostic (3.46e-2)" "unprognostic (1.83e-2)" "unprognostic (1.34e-3)" "unprognostic (1.21e-1)" "unprognostic (1.92e-1)" "unprognostic (3.04e-2)" "unprognostic (4.25e-2)" "unprognostic (2.74e-3)" "unprognostic (2.47e-2)" "unprognostic (1.10e-1)" "unprognostic (1.28e-2)" "unprognostic (1.46e-2)" 20.8 2.6 3.5 6.7 4.3 0.1 18.8 2.6 3.3 21.0 11.2 18.6 14.2 12.5 10.6 22.3 14.3 17.7 5.3 3.7 3.0 10.3 10.3 10.4 4.3 4.2 5.4 22.4 18.9 9.1 7.1 11.5 3.4 10.5 25.6 1.8 32.9 10.4 4.0 35.9 13.4 15.4 4.5 8.7 17.9 3.3 4.1 12.2 58.2 7.8 9.6 18.6 18.5 7.6 3.9 3.6 13.6 1.0 24.2 28.0 3.1 9.2 26.4 8.7 9.3 10.9 5.0 3.7 18.3 10.3 10.5 17.9 5.1 23.3 6.3 28.1 17.8 0.9 6.3 5.4 4.7 1.6 0.4 27.9 49.8 9.3 19.8 16.9 24.1 4.2 0.2 4.5 5.8 1.8 4.5 0.1 14.4 4.6 5.5 0.0 11.5 9.2 6.7 19.8 13.8 0.0 8.1 5.0 8.6 19.0 9.3 0.2 10.4 11.8 8.1 7.1 12.2 1.9 0.0 0.0 2.5 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 4.3 2.6 3.3 3.7 3.0 4.2 5.4 3.4 4.5 4.1 7.6 17.1 16.0 24.6 17.9 0.1 22.4 8.2 42.8 44.9 3.8 6.3 10.3 3.7 34.3 23.0 1.8 0.0 0.8 0.5 24.5 0.0 11.8 0.3 8.2 37.0 16.2 11.5 0.0 1.8 18.1 0.5 19.6 23.4 4.6 0.0 0.1 12.1 7.3 2.6 3.3 6.0 11.4 16.2 0.3 8.2 1.8 27.1 0.4 3.6 9.4 0.0 3.4 0.0 3.5 22.4 7.4 15.6 29.0 1.8 4.4 8.7 4.9 14.1 0.2 6.6 10.6 11.3 0.5 2.0 25.3 22.4 0.3 1.0 15.0 31.5 4.7 LRRC1 "dJ523E19.1, FLJ10775, FLJ11834, LANO" ENSG00000137269 "Leucine rich repeat containing 1" Q9BTT6 6 53794497-53924125 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 115.1;Late spermatids: 117.0;Oligodendrocytes: 138.8;Syncytiotrophoblasts: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RT4: 57.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031603, HPA031604" Enhanced Supported Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA031603: AB_10601753, HPA031604: AB_10601224" "unprognostic (2.90e-1)" "unprognostic (8.01e-2)" "unprognostic (9.59e-3)" "unprognostic (2.46e-2)" "unprognostic (7.04e-3)" "unprognostic (1.55e-2)" "unprognostic (2.19e-3)" "unprognostic (6.37e-2)" "unprognostic (7.02e-2)" "unprognostic (7.12e-3)" "prognostic unfavorable (1.18e-4)" "unprognostic (3.97e-1)" "prognostic favorable (2.21e-7)" "unprognostic (1.74e-1)" "unprognostic (2.31e-1)" "unprognostic (2.09e-1)" "unprognostic (9.84e-3)" 14.0 2.2 8.7 5.1 13.8 2.9 13.3 10.1 11.2 13.2 13.7 25.5 17.3 5.1 7.5 18.2 8.5 7.8 4.2 9.2 10.4 7.7 0.8 7.6 2.7 13.9 10.8 4.8 8.8 22.6 7.9 11.1 14.2 8.7 25.4 7.1 16.7 6.7 1.5 22.5 18.1 5.1 10.9 1.5 14.8 14.5 11.1 13.9 15.3 1.4 10.7 14.5 18.0 24.1 45.2 5.7 6.1 10.9 1.6 0.8 42.8 6.1 12.3 5.2 7.1 49.4 21.7 6.4 4.9 3.9 9.7 21.7 47.9 19.4 6.6 7.9 13.8 3.9 4.5 33.5 15.2 4.9 2.9 1.6 15.8 0.4 11.5 8.1 9.4 23.1 0.9 5.8 2.9 19.7 33.6 0.6 4.8 33.5 4.2 6.8 10.2 3.3 14.1 57.4 15.7 1.5 7.3 31.7 9.9 15.2 20.6 5.0 4.3 3.9 12.6 0.2 5.6 5.8 4.9 4.6 4.4 6.7 4.8 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.2 0.2 0.3 0.5 0.1 0.1 0.0 0.7 0.0 0.3 0.0 0.0 8.7 13.8 10.1 11.2 9.2 10.4 13.9 10.8 14.2 10.9 11.1 24.1 19.8 41.7 3.9 53.2 2.9 52.6 25.5 16.3 12.0 43.0 16.0 8.1 3.5 11.5 20.6 16.5 4.2 54.5 2.3 115.1 7.9 20.5 88.5 38.8 9.4 18.8 18.0 1.7 11.9 15.6 62.0 5.9 26.0 74.3 5.7 10.5 8.6 0.3 5.1 8.4 21.9 23.6 12.2 0.6 7.1 117.0 9.3 1.3 10.6 26.2 2.5 32.7 6.2 35.2 138.8 29.5 62.5 10.1 4.2 18.5 32.5 12.3 14.1 3.0 6.6 3.5 3.7 27.3 7.3 19.9 52.7 107.4 3.1 1.6 24.5 32.5 LRRC18 "MGC34773, UNQ933, UNQ9338, VKGE9338" ENSG00000165383 "Leucine rich repeat containing 18" Q8N456 10 48909483-48914232 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "choroid plexus: 12.1;fallopian tube: 7.6;testis: 14.0" "Group enriched" "Detected in some" 8 "Early spermatids: 222.0;Late spermatids: 64.1" "Cancer enhanced" "Detected in single" "endometrial cancer: 1.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA039256, HPA076699" Enhanced Approved Cytosol NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "HPA039256: AB_10671873, HPA076699: " "unprognostic (1.31e-2)" "unprognostic (3.66e-2)" "unprognostic (9.83e-4)" "unprognostic (3.10e-1)" "unprognostic (4.82e-2)" "unprognostic (1.98e-1)" "unprognostic (2.00e-1)" "unprognostic (8.11e-2)" "unprognostic (1.11e-1)" "unprognostic (3.16e-2)" "unprognostic (8.57e-3)" "unprognostic (4.08e-1)" "unprognostic (1.13e-1)" 0.0 0.0 0.3 0.4 0.2 0.4 0.3 0.5 0.3 0.6 12.1 0.4 0.2 0.2 0.0 0.1 7.6 0.3 0.3 0.8 0.3 0.0 0.0 1.5 0.2 1.0 0.9 0.1 0.0 0.0 0.0 0.0 0.8 0.2 0.7 0.0 0.1 0.0 0.0 0.8 0.4 0.2 0.6 0.1 0.2 14.0 0.6 0.0 0.0 0.0 0.1 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.5 0.3 0.8 0.3 1.0 0.9 0.8 0.6 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 222.0 6.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.3 64.1 1.8 0.1 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 17.8 0.0 0.0 0.0 0.2 2.8 0.6 0.0 0.1 0.0 0.0 0.2 0.0 0.0 LRRC37B ENSG00000185158 "Leucine rich repeat containing 37B" Q96QE4 17 32007872-32053504 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.1" "Cell type enhanced" "Detected in many" "Early spermatids: 101.9;Excitatory neurons: 45.4;Spermatocytes: 66.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 3.8" "Group enriched" "Detected in many" 4 "granulocytes: 1.5;NK-cells: 3.8;T-cells: 2.6" "Low cell line specificity" "Detected in all" HPA015135 Approved Approved Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA015135: AB_1853309" "unprognostic (5.46e-3)" "unprognostic (2.56e-2)" "unprognostic (5.08e-2)" "unprognostic (5.30e-2)" "unprognostic (2.39e-1)" "unprognostic (1.04e-1)" "unprognostic (3.60e-2)" "unprognostic (9.65e-3)" "unprognostic (5.06e-2)" "unprognostic (3.19e-2)" "unprognostic (1.72e-4)" "unprognostic (6.99e-2)" "unprognostic (5.72e-3)" "unprognostic (6.94e-2)" "unprognostic (3.35e-2)" "unprognostic (4.97e-2)" "unprognostic (1.36e-3)" 4.7 3.7 7.5 3.7 6.6 25.1 5.2 13.7 10.3 6.9 0.9 4.9 3.4 6.2 4.7 4.2 6.8 3.6 2.6 8.0 4.2 3.6 2.1 5.6 4.6 4.8 3.4 9.1 3.2 5.7 8.3 3.5 5.2 4.7 4.6 6.9 4.7 2.8 3.5 10.5 5.0 5.2 2.2 6.2 5.0 17.9 5.1 10.9 4.1 1.4 4.5 4.6 5.9 7.1 2.7 5.0 15.6 8.9 3.9 4.7 4.8 2.4 9.0 6.9 8.7 6.8 2.6 7.1 5.0 5.5 8.5 3.6 9.3 1.9 5.4 2.2 7.6 3.4 8.1 2.6 5.8 13.3 5.8 5.1 5.9 6.3 15.9 6.6 5.9 12.1 8.2 6.8 2.6 2.5 23.4 20.5 4.8 2.5 3.3 16.2 3.7 5.9 3.9 6.6 2.9 5.0 6.1 3.8 8.8 5.2 10.4 20.9 5.0 4.8 3.2 10.8 6.1 6.8 10.4 7.5 3.4 13.2 3.4 0.0 0.2 1.5 0.5 0.2 1.0 0.1 1.0 1.4 0.4 0.4 1.4 0.4 0.5 3.8 0.1 0.6 2.6 0.3 7.5 6.6 13.7 10.3 8.0 4.2 4.8 3.4 5.2 2.2 5.1 7.1 7.4 6.4 9.1 39.2 5.1 4.1 6.9 3.8 2.8 10.0 7.3 5.6 4.7 7.2 7.1 1.8 0.0 2.3 10.0 2.9 9.8 8.9 101.9 7.9 6.3 6.0 1.8 7.4 45.4 10.5 2.3 6.0 1.5 4.7 3.8 7.0 8.2 2.9 9.7 3.3 33.4 5.7 4.1 8.7 6.9 22.9 6.8 7.9 8.8 14.0 9.3 14.5 20.6 39.7 28.3 9.2 1.8 7.2 3.8 9.1 6.8 8.3 7.8 9.7 0.0 8.9 7.8 66.7 13.0 1.6 5.1 2.2 9.0 4.6 4.8 7.7 LRRC46 MGC16309 ENSG00000141294 "Leucine rich repeat containing 46" Q96FV0 17 47831634-47837719 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "fallopian tube: 78.4;testis: 54.3" "Group enriched" "Detected in some" 6 "Early spermatids: 143.1;Endometrial ciliated cells: 166.7;Late spermatids: 61.5;Respiratory ciliated cells: 225.8;Spermatocytes: 125.7" "Cancer enriched" "Detected in many" 5 "endometrial cancer: 11.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "T-47d: 3.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA021882, HPA074893" Enhanced Approved Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA021882: AB_1853320, HPA074893: AB_2732271" "unprognostic (1.06e-1)" "unprognostic (6.01e-2)" "unprognostic (9.24e-2)" "prognostic favorable (2.11e-4)" "unprognostic (1.40e-1)" "unprognostic (2.81e-2)" "unprognostic (4.27e-2)" "unprognostic (1.61e-1)" "unprognostic (1.27e-1)" "unprognostic (3.06e-1)" "unprognostic (2.21e-3)" "unprognostic (3.63e-2)" "unprognostic (2.98e-3)" "unprognostic (1.10e-1)" "unprognostic (1.46e-1)" "unprognostic (1.62e-1)" "unprognostic (2.14e-1)" 0.2 0.3 1.4 0.1 1.0 0.5 0.3 1.3 0.8 2.6 4.2 0.1 0.1 1.1 0.9 0.2 78.4 0.2 0.3 1.0 1.8 0.7 0.5 4.8 0.3 2.4 6.7 0.3 0.5 0.2 1.7 0.1 3.2 0.5 0.0 2.3 0.3 0.3 0.1 0.1 0.2 0.0 3.1 0.5 0.2 54.3 1.3 0.4 0.9 0.0 0.1 0.2 0.2 2.1 0.7 2.8 0.3 1.4 0.2 0.4 0.8 0.1 0.8 0.7 1.3 1.1 0.7 0.2 1.7 0.3 0.8 0.7 0.3 0.6 1.1 1.1 1.2 0.6 0.9 0.5 0.1 0.0 0.7 0.0 0.5 1.7 0.5 0.2 0.1 0.4 0.6 0.4 1.1 1.2 1.1 0.0 0.1 0.2 0.4 0.9 0.0 0.6 1.4 0.5 1.2 0.9 0.3 0.0 0.5 0.1 3.6 0.1 0.2 1.6 0.5 0.2 0.2 0.6 0.5 0.5 1.1 0.2 0.1 1.3 0.4 0.5 0.0 0.5 0.0 0.1 0.0 0.3 0.7 0.1 0.2 0.0 0.5 0.8 0.4 0.3 0.0 0.1 1.4 1.0 1.3 0.8 1.0 1.8 2.4 6.7 3.2 3.1 1.3 2.1 0.3 0.0 2.3 0.0 0.5 0.0 0.3 9.7 0.0 0.6 0.7 0.9 0.5 1.5 21.9 5.5 2.1 0.1 0.4 0.2 0.0 0.9 143.1 166.7 1.9 0.4 0.0 0.4 0.2 0.0 0.5 1.2 0.0 3.3 0.0 0.3 0.0 0.1 0.5 0.0 0.3 0.6 12.2 0.0 0.3 61.5 2.8 1.0 0.0 1.0 0.8 1.0 0.0 0.0 0.4 0.6 1.1 1.9 0.2 0.3 0.1 1.4 225.8 7.0 0.0 0.4 3.7 125.7 4.2 0.0 0.0 0.1 0.7 0.3 0.0 0.2 LRRC4C "KIAA1580, NGL-1" ENSG00000148948 "Leucine rich repeat containing 4C" Q9HCJ2 11 40114203-41459773 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.4;retina: 17.1" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 5497.5" "Cancer enhanced" "Detected in some" "glioma: 3.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "AF22: 19.1;U-2 OS: 20.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054800, HPA075816" Supported Approved Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "HPA054800: AB_2682603, HPA075816: " "unprognostic (4.86e-3)" "unprognostic (3.43e-2)" "unprognostic (7.62e-3)" "unprognostic (4.87e-3)" "unprognostic (6.48e-2)" "unprognostic (1.42e-1)" "unprognostic (2.84e-1)" "unprognostic (4.64e-2)" "unprognostic (1.93e-1)" "unprognostic (2.22e-1)" "unprognostic (2.44e-1)" "unprognostic (1.49e-1)" "unprognostic (4.90e-13)" "unprognostic (5.05e-4)" "unprognostic (5.21e-1)" "unprognostic (1.12e-1)" "unprognostic (6.45e-3)" 0.7 3.4 11.4 0.8 14.1 0.0 1.4 0.5 15.4 3.0 0.0 2.5 0.4 1.2 0.3 0.4 0.5 0.8 2.1 14.4 9.6 0.3 1.1 0.8 0.7 7.8 10.7 0.6 0.3 1.7 4.0 0.0 5.7 0.6 0.7 17.1 0.6 1.6 0.3 0.2 0.8 1.3 4.6 0.6 0.5 0.2 8.1 0.6 2.3 0.7 0.7 0.7 2.0 9.2 0.0 0.0 19.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 20.9 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 14.1 0.5 15.4 14.4 9.6 7.8 10.7 5.7 4.6 8.1 9.2 0.2 0.0 1.3 498.2 0.2 0.1 0.0 1.4 0.0 35.5 4.2 3.0 1.2 0.0 1.4 0.0 6.2 0.0 0.0 0.0 1.9 0.0 0.9 0.3 10.5 1.4 0.0 0.0 1171.8 0.0 0.0 5.6 0.0 0.9 0.0 0.1 0.0 0.0 0.1 8.4 1274.6 0.0 0.0 0.0 1.9 0.2 2.1 0.4 1.8 49.6 0.0 93.6 0.0 5497.5 221.3 0.3 0.0 1.5 0.1 0.1 0.0 0.7 0.0 99.7 0.0 2.0 0.7 0.3 0.5 0.0 0.0 0.0 0.0 2.3 0.0 0.0 LRRC73 "C6orf154, dJ337H4.2" ENSG00000204052 "Leucine rich repeat containing 73" Q5JTD7 6 43506969-43510686 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 44.2" "Group enriched" "Detected in many" 4 "Early spermatids: 411.0;Spermatocytes: 121.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 3.1;MCF7: 3.2;OE19: 4.5;T-47d: 3.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046698 Enhanced Approved Cytosol NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 21: OE19 - Mitochondria" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol "HPA046698: AB_10959526" "unprognostic (3.23e-2)" "unprognostic (1.03e-1)" "unprognostic (2.13e-1)" "unprognostic (4.42e-3)" "unprognostic (1.04e-2)" "unprognostic (3.52e-1)" "unprognostic (6.08e-3)" "unprognostic (1.19e-1)" "unprognostic (2.25e-1)" "unprognostic (1.01e-1)" "unprognostic (2.24e-2)" "unprognostic (1.93e-1)" "unprognostic (1.81e-1)" "unprognostic (2.72e-1)" "unprognostic (1.46e-1)" "unprognostic (1.76e-3)" "unprognostic (1.89e-2)" 0.2 6.4 4.6 0.0 4.8 0.0 0.3 0.0 8.9 0.9 0.6 0.4 0.6 0.6 0.3 0.2 5.1 0.5 1.5 5.6 2.4 2.6 0.5 0.9 0.0 1.3 1.4 0.9 1.2 2.9 4.7 0.2 1.5 1.0 0.1 1.3 0.6 0.6 0.0 0.3 0.2 0.3 0.2 0.5 1.0 44.2 3.5 0.0 1.1 0.0 0.0 0.4 0.3 3.7 0.3 0.7 0.4 3.1 0.5 1.5 0.1 0.1 0.9 0.2 0.1 0.0 0.1 0.1 0.0 0.5 0.4 1.2 0.3 0.4 0.0 0.0 0.5 0.0 0.2 0.1 0.4 0.0 0.0 0.2 0.6 1.0 0.1 1.5 0.1 0.1 0.2 0.3 0.6 3.2 0.0 0.0 0.0 4.5 0.4 0.0 0.0 0.0 0.8 0.0 1.1 1.3 0.3 0.2 0.1 0.0 3.2 0.0 0.1 0.2 0.3 1.1 0.1 0.3 0.2 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 4.8 0.0 8.9 5.6 2.4 1.3 1.4 1.5 0.2 3.5 3.7 0.3 0.0 0.0 1.0 0.0 0.4 3.1 0.7 0.0 5.6 0.8 1.3 1.0 1.5 1.6 3.7 0.0 0.1 0.0 1.0 7.9 0.6 411.0 27.1 4.0 0.6 5.4 0.0 3.3 0.9 0.1 0.8 1.5 1.3 0.0 0.6 0.0 0.8 0.1 28.6 3.3 2.2 0.0 0.0 0.0 58.3 4.4 0.4 1.8 0.0 0.0 8.7 0.0 0.0 0.3 0.2 0.1 4.1 0.0 2.8 2.2 9.4 12.6 8.4 6.6 0.3 0.9 121.6 12.4 0.0 0.0 0.3 0.1 7.1 0.8 0.6 LRRFIP1 "FLAP-1, FLIIAP1, GCF-2, HUFI-1, TRIP" ENSG00000124831 "LRR binding FLII interacting protein 1" Q32MZ4 2 237627587-237813682 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 322.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006979 Approved Supported Cytosol NA NA 580000 "Cluster 52: Eosinophils - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" Cytosol "HPA006979: AB_1079282" "unprognostic (2.07e-1)" "unprognostic (2.99e-2)" "unprognostic (4.09e-1)" "unprognostic (5.96e-2)" "unprognostic (1.22e-3)" "unprognostic (1.24e-1)" "unprognostic (1.09e-1)" "unprognostic (6.50e-2)" "unprognostic (9.68e-3)" "unprognostic (3.08e-2)" "unprognostic (3.99e-3)" "unprognostic (8.90e-2)" "unprognostic (4.70e-2)" "unprognostic (7.29e-2)" "unprognostic (2.69e-2)" "unprognostic (8.07e-2)" "unprognostic (7.64e-2)" 44.2 21.0 11.3 49.2 9.0 86.8 34.0 3.8 11.0 34.1 23.0 63.2 35.9 64.3 15.7 58.2 32.1 39.4 69.7 11.7 10.8 51.7 48.9 61.7 45.4 7.3 6.9 16.0 21.2 55.1 14.8 41.4 7.0 40.9 40.3 6.4 38.0 31.2 111.0 23.7 35.9 58.8 5.9 45.7 49.6 5.4 9.4 43.5 37.8 50.7 52.6 69.4 43.4 7.3 99.1 50.1 17.5 45.9 25.4 55.6 77.7 67.4 62.3 37.8 37.2 19.2 64.6 8.4 27.4 108.8 81.2 80.9 54.0 100.4 80.2 322.6 34.7 78.0 55.1 54.8 58.5 104.2 71.0 23.9 205.8 88.2 216.0 50.6 59.8 54.0 58.4 77.8 79.5 47.8 60.5 79.5 29.6 73.3 45.1 87.9 125.3 80.1 122.0 141.8 46.3 24.0 33.5 76.2 92.2 37.6 42.9 129.2 99.4 42.4 41.1 49.5 77.0 15.8 14.3 53.2 63.4 102.7 51.0 78.5 104.1 248.4 74.8 97.5 55.1 55.9 89.0 77.3 84.1 60.1 46.1 52.2 326.2 46.9 168.9 73.1 76.7 61.4 11.3 9.0 3.8 11.0 11.7 10.8 7.3 6.9 7.0 5.9 9.4 7.3 236.4 487.2 307.3 35.6 249.6 307.0 391.9 166.0 113.3 46.4 128.6 86.2 160.3 127.2 269.9 172.9 37.5 111.2 347.1 319.5 52.8 229.7 7.9 368.3 88.2 213.0 190.5 62.4 175.9 333.0 359.2 109.1 159.0 426.3 241.0 56.9 122.0 149.1 175.8 21.9 237.5 168.3 79.3 271.2 721.3 7.9 29.8 398.9 167.2 57.1 365.0 25.1 213.1 111.1 12.5 389.6 220.6 23.3 146.6 430.5 152.8 49.5 286.1 6.0 78.9 147.3 182.9 10.1 27.4 179.3 243.1 25.3 288.5 158.3 150.0 588.4 LRSAM1 "CMT2P, FLJ31641, RIFLE, TAL" ENSG00000148356 "Leucine rich repeat and sterile alpha motif containing 1" Q6UWE0 9 127451489-127503499 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" Transferase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 32.0;Excitatory neurons: 28.6;Inhibitory neurons: 26.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021403, HPA021844, CAB037304" Supported Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "CAB037304: AB_2138198, HPA021403: AB_1853366, HPA021844: AB_1853368" "unprognostic (8.83e-2)" "unprognostic (3.13e-1)" "unprognostic (7.48e-3)" "unprognostic (4.15e-3)" "unprognostic (9.42e-2)" "unprognostic (2.05e-1)" "unprognostic (1.64e-1)" "unprognostic (5.00e-2)" "unprognostic (1.66e-1)" "unprognostic (2.72e-2)" "prognostic favorable (6.78e-6)" "unprognostic (1.27e-1)" "prognostic favorable (5.72e-4)" "unprognostic (1.94e-2)" "unprognostic (3.26e-1)" "unprognostic (9.07e-2)" "unprognostic (3.33e-2)" 7.2 9.8 8.6 3.4 8.6 2.0 7.3 7.3 12.5 10.7 5.2 16.5 3.4 9.0 5.9 8.7 7.8 3.9 17.3 8.8 8.8 9.0 8.8 7.4 4.5 11.1 7.6 10.7 5.7 6.9 9.0 3.4 11.4 9.1 2.6 2.3 7.5 5.6 13.5 21.2 9.1 5.0 7.0 9.5 9.5 4.3 7.9 3.4 8.8 7.2 3.2 12.3 10.2 9.0 5.7 10.8 4.8 10.7 9.8 9.1 8.3 5.3 8.1 10.0 7.6 8.9 5.9 9.8 5.9 9.9 3.6 18.7 7.8 13.3 3.8 11.5 5.3 5.2 9.0 10.2 9.4 6.2 7.3 6.1 7.9 6.1 12.2 10.7 11.2 7.6 4.8 7.6 4.5 17.6 3.9 4.5 4.7 17.4 9.3 7.1 5.6 18.4 11.5 5.1 9.8 9.2 4.1 12.6 8.8 4.3 26.5 3.2 10.2 4.6 5.6 4.2 2.5 6.2 7.9 1.1 9.1 4.5 2.6 18.5 4.8 21.3 3.7 6.5 4.7 3.7 2.8 3.5 6.1 2.7 1.1 1.4 4.0 1.3 6.8 3.6 2.3 3.8 8.6 8.6 7.3 12.5 8.8 8.8 11.1 7.6 11.4 7.0 7.9 9.0 5.3 9.6 3.9 32.0 5.1 1.1 3.1 2.9 4.6 6.7 5.2 5.0 20.4 4.3 7.3 0.0 6.2 5.0 5.3 6.0 5.9 7.1 0.6 3.6 4.7 4.8 1.2 2.5 28.6 1.4 2.1 4.9 12.2 4.6 9.5 6.6 3.3 7.1 6.3 11.8 26.9 5.8 14.2 5.6 3.7 1.2 2.8 7.4 3.6 10.3 7.4 4.7 3.1 18.1 21.0 4.7 5.0 5.3 3.9 5.0 6.6 5.8 6.0 5.2 0.0 5.1 6.0 5.7 3.6 5.8 2.7 7.0 5.6 3.9 4.8 3.3 LRTM2 ENSG00000166159 "Leucine rich repeats and transmembrane domains 2" Q8N967 12 1820267-1836753 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 11.8" "Group enriched" "Detected in some" 4 "Bipolar cells: 7.9;Excitatory neurons: 10.2;Horizontal cells: 11.8;Inhibitory neurons: 7.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HEL: 4.3;SCLC-21H: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA055094, HPA062745" Uncertain Approved Cytosol NA NA "Cluster 65: Brain - Ion transport" "Cluster 36: HEL - Hemostasis" "Cluster 62: Horizontal cells - Visual perception" Cytosol "HPA055094: AB_2682693, HPA062745: " "unprognostic (1.84e-3)" "unprognostic (4.83e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-1)" "unprognostic (5.49e-2)" "unprognostic (1.60e-1)" "unprognostic (1.34e-3)" "unprognostic (2.25e-1)" "unprognostic (1.24e-1)" "unprognostic (6.20e-4)" "unprognostic (2.21e-1)" "unprognostic (8.02e-2)" 0.0 0.0 2.9 0.0 11.4 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 3.6 0.0 0.0 0.0 0.0 0.6 4.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 11.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 11.4 0.0 3.8 3.9 3.6 0.6 4.8 0.5 0.2 11.8 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 7.8 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 LSAMP "IGLON3, LAMP" ENSG00000185565 "Limbic system associated membrane protein" Q13449 3 115802363-117139389 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.9;retina: 41.3" "Group enriched" "Detected in many" 9 "Astrocytes: 3381.0;Excitatory neurons: 1001.8;Inhibitory neurons: 2137.4;Oligodendrocyte precursor cells: 2480.6;Oligodendrocytes: 933.9" "Cancer enhanced" "Detected in many" "glioma: 13.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 11.0;SH-SY5Y: 22.5;WM-115: 55.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054051, HPA076122" Enhanced Cytosol NA NA 150000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 58: Brain - Synaptic function" "Cluster 17: WM-115 - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol "HPA054051: AB_2682358, HPA076122: AB_2686779" "unprognostic (4.18e-2)" "unprognostic (2.54e-1)" "unprognostic (9.97e-3)" "unprognostic (6.03e-2)" "unprognostic (9.63e-2)" "unprognostic (4.15e-3)" "unprognostic (6.81e-2)" "unprognostic (2.70e-2)" "unprognostic (5.71e-2)" "unprognostic (6.82e-3)" "unprognostic (1.26e-1)" "unprognostic (6.03e-2)" "unprognostic (1.92e-2)" "unprognostic (1.28e-2)" "unprognostic (1.06e-1)" "unprognostic (5.23e-5)" "unprognostic (1.31e-2)" 3.1 15.7 47.8 5.6 45.4 1.0 1.7 22.6 73.9 21.8 0.0 9.9 2.0 5.0 3.1 3.9 3.1 13.5 2.3 64.2 36.3 2.6 0.8 10.6 4.9 37.5 32.2 5.5 14.4 8.9 3.8 1.0 37.8 26.1 3.8 41.3 1.2 7.3 0.2 5.1 2.6 3.8 28.5 1.9 3.8 4.6 56.4 1.2 5.0 0.2 6.7 6.5 4.8 31.9 0.2 3.2 11.0 0.3 1.1 3.4 1.1 1.0 0.5 0.4 1.1 0.2 0.7 0.8 0.2 6.0 0.3 0.2 0.2 0.1 0.5 0.5 0.1 0.3 1.0 0.3 0.2 0.8 0.5 2.8 0.0 1.3 0.1 0.2 0.1 1.3 0.4 1.2 0.0 0.3 1.3 0.8 4.1 0.1 0.9 0.2 0.2 0.2 2.8 1.1 2.4 22.5 0.0 0.2 3.5 4.5 0.3 0.8 0.0 2.0 1.5 2.7 0.6 1.3 1.2 0.3 0.4 0.3 55.9 0.9 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.3 0.2 0.1 0.4 0.0 0.1 0.1 0.1 0.0 47.8 45.4 22.6 73.9 64.2 36.3 37.5 32.2 37.8 28.5 56.4 31.9 0.5 0.0 1.1 3381.0 0.6 7.6 0.3 0.0 0.0 54.2 1.2 0.4 25.5 4.3 0.6 0.0 2.1 0.2 0.0 0.0 0.0 0.0 22.5 0.9 26.5 5.8 0.0 0.0 1001.8 3.6 0.0 25.0 2.6 1.1 0.0 20.1 4.2 0.0 0.3 220.4 2137.4 0.0 0.0 0.0 3.2 22.2 126.2 1.9 56.9 111.5 0.0 126.9 0.0 2480.6 933.9 0.4 0.0 91.7 1.0 18.3 0.0 0.2 0.0 11.3 0.0 0.1 4.0 0.9 0.5 0.6 5.1 0.0 0.4 4.9 0.0 0.6 LSM12 FLJ30656 ENSG00000161654 "LSM12 homolog" Q3MHD2 17 44034328-44067619 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 267.0;Late spermatids: 568.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051934 Approved Approved Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" Cytosol "HPA051934: AB_2681666" "unprognostic (3.42e-2)" "unprognostic (1.01e-2)" "unprognostic (1.64e-1)" "unprognostic (5.98e-2)" "unprognostic (8.04e-2)" "unprognostic (3.87e-3)" "prognostic unfavorable (1.05e-4)" "unprognostic (1.79e-2)" "unprognostic (1.17e-1)" "unprognostic (4.30e-2)" "prognostic unfavorable (7.49e-5)" "unprognostic (3.76e-1)" "prognostic unfavorable (1.18e-7)" "unprognostic (8.91e-3)" "unprognostic (2.79e-2)" "unprognostic (5.04e-2)" "unprognostic (3.18e-2)" 20.0 21.9 20.0 16.9 20.5 29.6 18.6 19.9 24.7 16.1 18.4 19.7 17.2 17.5 25.0 28.1 15.1 15.5 22.6 20.8 23.5 20.8 29.3 16.8 20.8 20.9 22.5 15.4 23.9 21.5 14.2 23.0 20.6 16.8 23.6 31.3 18.1 15.4 37.1 16.7 16.9 20.4 19.6 17.2 19.9 24.0 21.6 19.9 18.2 23.7 24.8 22.8 17.4 21.0 47.4 51.3 35.7 56.3 45.9 49.4 65.2 52.3 51.6 65.5 65.3 59.2 50.5 78.6 36.8 59.8 51.9 37.9 75.7 67.7 97.7 59.5 78.5 54.5 38.7 72.6 42.4 95.6 55.9 44.4 53.8 61.3 88.0 42.7 57.1 50.2 81.0 56.6 44.8 46.5 91.4 53.1 52.8 46.7 72.5 57.3 69.8 76.2 61.4 68.5 49.6 32.9 42.4 45.3 55.9 74.0 94.5 62.5 51.8 82.7 49.0 45.1 86.5 44.4 48.3 83.6 70.2 66.9 64.0 43.8 61.7 28.3 48.3 80.3 54.0 46.7 53.5 51.8 70.7 41.0 46.9 46.6 32.6 47.1 78.4 71.9 58.2 61.2 20.0 20.5 19.9 24.7 20.8 23.5 20.9 22.5 20.6 19.6 21.6 21.0 37.9 16.0 17.5 4.6 32.0 50.3 44.0 36.7 42.1 41.4 58.4 44.6 19.3 27.1 27.4 16.5 87.6 48.0 50.4 43.9 43.0 62.7 267.0 57.2 51.2 35.5 39.9 45.8 13.3 101.6 94.0 37.2 28.5 52.3 7.6 39.6 28.9 48.6 43.8 35.3 14.3 46.5 26.4 38.0 64.4 568.8 35.1 44.6 33.8 14.0 50.1 35.4 39.1 8.0 14.8 85.2 38.5 31.6 48.0 76.7 30.3 58.4 22.7 63.1 26.3 35.5 57.9 59.7 70.0 50.5 48.9 83.7 37.8 63.7 48.5 78.6 LTN1 "C21orf10, C21orf98, FLJ11053, KIAA0714, LISTERIN, RNF160, ZNF294" ENSG00000198862 "Listerin E3 ubiquitin protein ligase 1" O94822 21 28928144-28992956 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 213.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029143, CAB034164, HPA055604" Uncertain Enhanced Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "CAB034164: AB_2180094, HPA029143: AB_10671360, HPA055604: AB_2682859" "unprognostic (3.67e-2)" "unprognostic (7.07e-2)" "unprognostic (7.78e-2)" "unprognostic (3.99e-1)" "unprognostic (1.42e-2)" "unprognostic (3.66e-3)" "unprognostic (5.38e-2)" "unprognostic (5.40e-2)" "unprognostic (9.98e-2)" "unprognostic (4.45e-2)" "unprognostic (2.85e-2)" "unprognostic (1.13e-1)" "unprognostic (9.87e-2)" "unprognostic (1.72e-1)" "unprognostic (8.22e-2)" "unprognostic (4.57e-2)" "unprognostic (1.52e-1)" 7.7 8.4 4.5 9.3 7.8 16.5 12.4 7.0 6.2 9.3 5.3 9.2 8.8 10.7 10.2 9.1 7.0 7.4 7.7 4.1 6.6 8.3 11.0 7.4 12.0 6.1 5.9 10.1 9.4 9.9 3.9 18.6 6.7 12.7 10.6 11.6 10.1 8.1 9.5 9.4 9.0 9.1 6.2 10.3 11.0 13.6 6.1 11.3 12.1 11.2 10.5 8.3 5.9 13.1 20.4 8.6 17.5 7.9 14.6 19.9 17.7 16.8 13.6 14.2 19.4 12.1 16.5 13.3 8.0 15.1 12.2 10.2 18.8 13.8 25.5 15.7 13.0 39.8 11.9 9.7 11.0 13.3 14.8 13.9 12.1 20.1 16.6 13.9 15.2 9.5 33.0 31.0 16.4 6.3 8.6 12.9 25.1 16.8 10.1 11.4 34.9 28.0 16.0 17.3 9.5 19.7 19.3 14.5 17.0 16.3 14.8 18.6 20.2 12.4 22.9 16.8 14.3 25.1 25.1 18.5 19.3 28.3 15.0 12.6 4.9 7.9 6.3 7.6 5.2 5.8 4.2 4.2 4.9 5.1 4.5 3.4 8.6 7.0 10.7 3.1 5.0 2.6 4.5 7.8 7.0 6.2 4.1 6.6 6.1 5.9 6.7 6.2 6.1 13.1 42.1 16.0 22.6 36.6 30.7 30.2 26.3 22.8 30.7 28.4 22.8 17.4 25.8 12.8 24.0 11.0 33.3 19.3 26.8 18.4 1.9 14.4 213.7 21.6 45.9 27.5 22.7 18.7 47.1 14.0 18.8 30.3 38.2 36.2 27.8 24.2 14.3 19.7 13.2 42.1 54.8 18.9 22.4 18.1 13.2 73.1 26.8 23.5 12.4 25.3 28.2 44.9 18.6 53.8 90.8 20.2 14.2 21.1 43.9 31.5 16.6 16.9 22.6 30.5 13.1 29.3 28.6 46.8 23.9 30.1 32.0 29.8 30.5 34.3 20.8 29.8 LYPD6 MGC52057 ENSG00000187123 "LY6/PLAUR domain containing 6" Q86Y78 2 149329985-149474138 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.0;placenta: 15.7" "Cell type enhanced" "Detected in many" "Astrocytes: 40.8;Early spermatids: 59.7;Inhibitory neurons: 65.9;Late spermatids: 230.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 37.6;fHDF/TERT166: 48.2;HBF TERT88: 25.0;LHCN-M2: 46.2;RT4: 39.9" "Low region specificity" "Detected in all" HPA042805 Enhanced Approved Cytosol "Secreted in other tissues" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA042805: AB_10794159" "unprognostic (1.77e-1)" "unprognostic (1.01e-1)" "unprognostic (7.23e-3)" "unprognostic (1.64e-2)" "unprognostic (3.25e-1)" "unprognostic (6.49e-3)" "unprognostic (6.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.73e-2)" "prognostic favorable (3.59e-4)" "unprognostic (4.14e-3)" "unprognostic (6.75e-2)" "unprognostic (7.33e-4)" "unprognostic (1.39e-1)" "unprognostic (1.94e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.72e-4)" 1.4 0.3 8.0 0.6 4.6 0.0 9.3 4.5 5.5 0.9 1.2 1.5 1.7 2.1 0.1 0.5 1.6 11.1 0.6 4.7 9.8 2.0 0.3 0.2 0.2 6.8 24.0 0.6 1.9 1.4 0.3 15.7 6.7 1.4 2.5 7.0 0.2 1.3 0.1 0.6 1.4 2.9 5.6 0.6 3.9 6.8 16.1 0.3 0.2 0.1 1.3 2.6 0.4 4.2 0.2 0.0 6.8 37.6 0.0 0.1 0.5 15.0 6.6 18.9 11.7 0.2 3.0 0.0 0.8 48.2 9.1 3.8 5.3 0.1 25.0 0.0 1.7 0.1 9.6 0.0 0.2 0.0 0.0 0.0 0.4 0.0 11.0 0.4 0.3 0.0 0.0 0.0 46.2 6.7 0.0 3.6 5.4 3.2 4.3 0.0 20.1 0.0 2.3 39.9 1.5 6.7 10.1 11.2 1.2 12.2 1.5 0.8 0.0 0.4 5.7 0.5 8.2 0.0 0.0 0.0 3.5 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 4.6 4.5 5.5 4.7 9.8 6.8 24.0 6.7 5.6 16.1 4.2 0.1 0.0 0.0 40.8 0.0 0.1 0.6 1.0 1.2 2.7 11.7 6.6 0.4 10.0 2.0 0.0 0.0 0.0 0.0 0.4 3.9 2.6 59.7 1.7 0.4 0.9 0.0 0.0 0.3 0.9 0.2 1.4 10.7 2.5 0.0 0.7 0.4 0.0 0.3 0.0 65.9 2.8 0.0 0.0 0.0 230.4 3.1 0.0 0.0 1.0 0.0 4.1 0.0 13.6 1.0 4.5 0.4 0.4 0.1 2.1 1.7 0.0 0.8 3.4 0.0 0.1 0.2 1.0 5.2 0.7 0.0 0.3 0.1 0.0 2.0 1.7 LYPLAL1 Q96AV0 ENSG00000143353 "Lysophospholipase like 1" Q5VWZ2 1 219173869-219212865 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 209.4;Proximal tubular cells: 349.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045806 Approved Supported Cytosol NA NA 8600 "Cluster 30: Non-specific - Translation" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA045806: AB_10966647" "unprognostic (1.27e-2)" "unprognostic (1.29e-1)" "unprognostic (3.98e-2)" "unprognostic (8.64e-2)" "unprognostic (2.41e-1)" "unprognostic (1.49e-1)" "unprognostic (2.01e-1)" "unprognostic (3.73e-2)" "unprognostic (4.08e-2)" "unprognostic (2.05e-1)" "unprognostic (1.16e-1)" "unprognostic (2.76e-2)" "prognostic favorable (1.31e-4)" "unprognostic (1.68e-1)" "unprognostic (5.87e-2)" "unprognostic (1.73e-1)" "unprognostic (4.65e-2)" 9.3 17.9 7.5 3.8 7.6 1.1 10.0 7.8 11.3 8.5 7.2 5.6 8.6 7.3 3.6 7.9 5.4 8.6 36.5 7.3 8.5 42.3 27.3 7.0 8.6 7.9 7.5 9.8 7.6 11.8 5.8 8.2 7.9 13.2 5.9 6.5 8.5 6.5 7.4 9.6 7.5 7.8 8.0 4.4 6.1 6.5 7.4 5.8 16.2 12.1 7.7 6.0 3.9 8.8 9.1 9.4 4.1 0.0 8.1 16.3 10.3 5.3 5.9 4.8 5.6 4.3 12.9 10.0 13.9 4.5 4.7 4.9 8.6 12.1 7.3 13.7 9.3 5.8 4.9 9.8 32.9 12.6 4.3 19.5 11.1 4.8 12.1 11.3 14.5 9.5 16.8 10.2 11.4 6.1 6.1 10.3 7.8 8.6 15.4 3.3 10.5 17.5 19.9 7.1 10.1 5.6 6.3 16.9 17.7 13.5 16.2 15.6 7.8 4.0 2.0 8.2 6.2 8.7 5.3 6.8 13.5 10.1 9.0 0.9 2.0 1.5 0.8 1.8 1.9 3.3 1.3 1.0 1.8 2.0 2.3 1.8 2.2 1.4 1.8 1.5 1.6 1.3 7.5 7.6 7.8 11.3 7.3 8.5 7.9 7.5 7.9 8.0 7.4 8.8 23.6 25.6 35.5 93.0 37.1 22.2 18.7 75.5 29.0 28.5 23.9 25.4 105.9 31.5 42.0 51.5 8.4 89.5 12.8 10.8 209.4 49.3 40.9 7.7 17.4 16.3 18.6 10.3 50.2 53.2 35.4 29.7 11.7 23.6 17.1 18.5 22.9 39.8 64.8 18.5 51.7 18.0 44.7 26.8 21.2 7.8 27.1 49.3 42.7 79.6 27.1 108.7 20.6 82.9 123.4 37.5 16.9 30.9 15.0 13.0 33.4 349.2 38.2 28.9 13.1 24.8 23.3 36.0 24.8 24.9 29.3 62.5 14.2 26.5 15.8 12.3 LYRM2 DJ122O8.2 ENSG00000083099 "LYR motif containing 2" Q9NU23 6 89568144-89638749 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063932 Uncertain Approved Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA063932: AB_2685155" "unprognostic (3.23e-2)" "unprognostic (1.47e-1)" "unprognostic (8.52e-3)" "unprognostic (8.49e-2)" "unprognostic (4.27e-2)" "unprognostic (6.26e-2)" "prognostic unfavorable (2.58e-8)" "unprognostic (1.46e-1)" "unprognostic (1.18e-1)" "unprognostic (3.29e-3)" "unprognostic (8.07e-3)" "unprognostic (3.63e-2)" "unprognostic (7.98e-2)" "unprognostic (3.70e-1)" "unprognostic (1.45e-1)" "unprognostic (2.23e-2)" "unprognostic (5.64e-2)" 10.7 15.9 11.6 10.3 12.3 14.8 14.1 11.2 12.3 9.4 9.1 13.7 8.6 11.1 14.3 12.3 13.4 10.2 17.4 12.5 12.4 17.4 12.4 10.1 12.8 11.2 11.9 9.9 10.5 22.5 10.7 13.9 11.1 13.2 16.1 9.0 9.8 8.6 21.3 6.2 9.5 11.9 12.5 9.0 13.0 8.7 12.5 9.2 25.2 16.9 10.9 10.7 6.6 12.7 18.4 9.6 32.1 19.7 16.0 24.0 12.8 31.3 22.2 24.0 23.8 8.6 9.6 25.1 29.5 29.6 35.7 16.5 20.6 29.7 30.8 32.0 36.5 39.8 9.9 7.3 24.0 42.6 29.7 29.7 28.2 27.2 36.5 19.4 18.8 27.0 41.8 32.0 27.9 16.5 10.0 15.3 7.6 14.9 12.5 20.7 40.1 18.9 27.2 18.1 35.7 24.2 18.3 11.1 31.1 14.6 15.8 43.0 30.2 15.0 13.2 27.4 44.0 22.9 35.1 13.0 31.6 30.3 28.9 16.4 21.0 14.3 21.5 24.8 23.1 32.6 24.0 28.4 19.7 30.9 26.8 25.1 6.0 27.3 33.9 26.1 24.2 14.8 11.6 12.3 11.2 12.3 12.5 12.4 11.2 11.9 11.1 12.5 12.5 12.7 37.1 41.7 50.3 11.8 47.6 11.9 29.0 43.1 29.0 27.0 37.6 45.7 87.5 27.1 48.3 27.6 16.7 87.6 33.9 31.3 93.9 40.1 66.0 86.2 56.6 30.7 40.7 35.3 17.6 49.4 32.9 35.6 37.2 55.8 32.9 33.9 24.7 27.1 57.8 25.2 19.7 43.4 44.7 35.1 12.9 18.7 30.7 39.9 30.2 15.9 44.8 100.6 44.3 13.0 26.4 40.1 32.8 27.1 30.9 25.9 29.3 68.8 70.6 45.3 52.6 39.2 41.1 57.0 31.6 43.3 16.2 72.4 37.5 81.8 39.8 26.2 LYSMD3 FLJ13542 ENSG00000176018 "LysM domain containing 3" Q7Z3D4 5 90515611-90529584 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018024 Approved Approved Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA018024: AB_2138525" "unprognostic (4.50e-2)" "unprognostic (1.85e-2)" "prognostic favorable (3.83e-4)" "unprognostic (5.59e-2)" "unprognostic (5.61e-2)" "unprognostic (9.80e-3)" "unprognostic (3.99e-2)" "unprognostic (4.66e-2)" "unprognostic (6.23e-2)" "unprognostic (1.22e-2)" "unprognostic (3.18e-2)" "unprognostic (2.02e-1)" "prognostic favorable (9.25e-4)" "unprognostic (1.81e-1)" "unprognostic (8.48e-2)" "unprognostic (4.97e-3)" "unprognostic (9.46e-2)" 10.4 14.3 4.2 12.6 4.5 11.7 11.6 7.9 6.3 14.2 10.8 12.3 12.8 12.1 5.2 10.2 7.4 13.4 12.0 4.4 5.4 13.6 24.1 13.3 12.6 4.3 5.7 15.0 9.0 18.2 7.5 17.1 4.5 13.1 11.3 11.4 11.5 10.2 9.7 6.3 11.9 11.0 4.4 11.4 9.7 6.0 5.2 12.5 18.0 16.3 12.6 10.6 5.5 6.3 17.5 11.6 14.5 15.4 22.2 22.4 14.3 27.3 29.5 18.6 30.2 9.9 17.6 21.6 11.5 24.1 29.1 8.7 22.5 26.6 36.3 16.0 14.2 16.4 14.2 16.2 23.0 13.9 26.5 16.6 18.4 17.1 28.5 19.9 27.1 13.6 15.9 32.1 21.1 15.5 16.1 8.1 7.1 4.4 19.4 14.8 24.5 31.0 20.5 11.9 4.4 8.8 16.2 12.1 22.6 11.4 14.0 12.9 34.1 11.2 15.8 24.8 20.1 36.2 24.7 18.2 18.9 23.3 17.9 53.7 11.5 18.1 9.2 14.4 14.7 9.6 10.5 11.4 11.2 8.4 14.1 12.3 17.2 18.5 15.3 5.3 12.7 11.4 4.2 4.5 7.9 6.3 4.4 5.4 4.3 5.7 4.5 4.4 5.2 6.3 18.6 35.3 27.1 8.8 22.0 14.3 10.1 9.7 11.4 10.3 20.3 14.6 25.0 7.2 18.0 12.9 4.2 10.2 27.3 16.6 1.9 7.1 1.2 17.1 21.7 15.7 21.6 12.6 13.4 8.1 10.8 20.0 15.8 24.6 26.0 10.6 21.4 32.9 8.7 20.2 13.5 17.3 10.2 16.7 23.5 1.9 16.8 19.2 7.2 10.3 13.5 21.5 11.3 14.6 18.8 7.7 9.2 13.2 41.5 16.4 14.5 12.9 14.5 13.7 19.7 15.9 16.7 7.5 5.5 13.4 16.6 14.0 21.5 10.9 12.0 13.0 LZTFL1 BBS17 ENSG00000163818 "Leucine zipper transcription factor like 1" Q9NQ48 3 45823316-45916042 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 119.0;Endometrial ciliated cells: 56.7;Respiratory ciliated cells: 142.2;Spermatocytes: 170.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043466, HPA048447" Enhanced Supported Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA043466: AB_2678491, HPA048447: AB_2680398" "unprognostic (1.64e-2)" "unprognostic (1.34e-1)" "unprognostic (3.14e-2)" "unprognostic (1.26e-2)" "unprognostic (2.65e-2)" "unprognostic (5.42e-2)" "unprognostic (1.15e-2)" "unprognostic (2.26e-2)" "unprognostic (4.20e-2)" "unprognostic (2.94e-2)" "unprognostic (7.83e-2)" "unprognostic (5.32e-2)" "unprognostic (1.30e-3)" "unprognostic (6.27e-3)" "unprognostic (8.31e-2)" "unprognostic (4.27e-3)" "unprognostic (4.19e-1)" 5.2 6.2 7.1 4.5 8.2 6.0 12.4 5.8 10.1 12.4 17.5 5.7 7.0 13.2 15.0 5.5 18.9 6.9 4.6 8.7 7.7 12.0 10.0 9.0 4.7 6.7 7.3 11.4 5.6 14.2 11.7 5.9 6.5 7.9 6.2 15.8 7.2 8.8 2.8 6.0 5.7 8.4 6.6 6.0 5.8 25.4 7.1 30.7 18.9 3.5 5.7 4.7 4.1 6.9 10.1 5.0 7.8 5.1 7.2 17.9 4.0 5.3 10.0 12.2 15.8 2.4 7.5 2.7 3.1 7.5 15.2 6.4 9.5 8.6 15.9 0.2 6.1 2.6 6.7 4.5 9.4 9.9 2.8 9.3 29.6 16.8 10.8 7.8 6.0 16.5 8.9 6.7 5.9 1.6 34.1 9.6 8.1 6.7 4.2 3.7 0.8 10.7 14.7 4.7 5.4 11.0 7.0 6.0 13.2 8.7 7.1 18.3 9.9 4.5 3.1 12.2 7.1 18.3 10.0 0.1 14.3 11.7 3.7 0.0 0.9 0.4 1.3 1.2 1.7 4.3 1.1 1.2 2.3 2.4 1.8 1.7 1.0 1.5 0.8 2.5 2.0 1.6 7.1 8.2 5.8 10.1 8.7 7.7 6.7 7.3 6.5 6.6 7.1 6.9 7.6 28.9 25.2 7.8 10.8 13.5 10.5 14.9 12.0 7.9 16.9 14.9 7.6 11.5 23.6 14.7 14.6 3.1 8.4 3.7 15.6 13.3 119.0 56.7 10.5 10.2 11.4 11.6 22.3 6.9 5.1 13.3 6.1 12.3 8.2 10.1 11.7 13.5 6.6 23.5 9.9 10.4 10.2 7.3 7.0 19.2 9.9 5.3 8.8 5.6 10.8 17.8 7.2 6.6 12.2 5.6 5.6 13.5 11.6 5.9 3.2 23.0 142.2 14.6 13.1 15.7 9.2 170.0 24.1 8.4 9.9 2.1 10.5 14.2 8.9 5.6 MACO1 "FLJ10747, TMEM57" ENSG00000204178 "Macoilin 1" Q8N5G2 1 25430858-25500209 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 38.8;Exocrine glandular cells: 62.3;Pancreatic endocrine cells: 48.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019680 Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA019680: AB_1858125" "unprognostic (2.42e-2)" "unprognostic (1.63e-1)" "unprognostic (1.54e-2)" "unprognostic (2.83e-2)" "unprognostic (2.16e-1)" "unprognostic (1.10e-2)" "unprognostic (5.39e-2)" "unprognostic (1.69e-2)" "unprognostic (6.40e-2)" "unprognostic (1.29e-1)" "unprognostic (2.71e-1)" "unprognostic (7.02e-2)" "prognostic favorable (7.13e-4)" "unprognostic (2.54e-2)" "unprognostic (4.22e-2)" "unprognostic (5.22e-2)" "unprognostic (5.35e-3)" 8.5 15.0 11.2 5.3 10.8 28.4 8.7 19.9 14.9 8.6 12.8 8.5 6.2 7.9 12.5 16.1 6.9 7.4 8.4 10.9 11.2 11.8 26.3 8.3 7.8 10.6 9.9 16.2 24.9 9.2 8.9 6.8 11.1 12.3 7.8 11.0 16.3 7.9 30.3 9.6 9.0 7.4 10.5 8.7 11.7 14.1 10.0 11.4 12.4 15.2 9.0 7.3 9.6 12.7 8.6 3.6 9.3 18.0 16.4 10.1 4.3 9.0 11.1 9.2 8.6 2.6 11.0 20.1 10.1 11.9 5.2 8.0 8.8 9.2 10.4 9.4 7.9 26.8 5.7 7.7 9.3 10.1 15.3 10.3 13.3 12.5 8.9 9.7 11.6 12.4 15.8 7.5 9.3 5.0 19.0 13.8 13.2 10.1 7.1 12.1 11.0 15.0 15.0 3.7 15.2 15.5 7.5 19.3 10.9 7.3 7.7 14.3 13.8 9.3 6.2 12.9 6.2 12.1 7.2 10.6 10.5 13.1 7.9 0.5 0.3 1.6 0.3 0.2 0.5 0.4 0.5 0.5 0.2 0.5 0.4 0.7 0.1 0.3 0.3 1.1 0.3 0.2 11.2 10.8 19.9 14.9 10.9 11.2 10.6 9.9 11.1 10.5 10.0 12.7 31.3 19.2 23.6 0.0 9.9 0.0 0.0 0.0 0.0 0.0 27.8 17.8 0.0 0.0 11.2 7.3 0.0 13.7 27.0 0.0 5.9 38.8 0.0 19.4 23.8 12.9 0.0 0.0 0.0 62.3 22.7 9.2 0.0 32.5 10.1 26.0 0.0 0.0 14.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.0 7.2 0.0 0.0 0.0 0.0 48.6 0.0 0.0 9.8 0.0 0.0 19.6 13.8 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 10.4 11.0 22.7 0.0 0.0 MAGEA1 "CT1.1, MAGE1, MGC9326" ENSG00000198681 "MAGE family member A1" P43355 X 153179284-153183880 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 46 "testis: 4.5" "Group enriched" "Detected in some" 36 "Spermatocytes: 26.2;Spermatogonia: 38.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 74.4;HMC-1: 123.9;RPMI-8226: 64.3;U-2 OS: 117.8;U-266/70: 177.4;U-266/84: 305.3" CAB002620 Enhanced Supported Cytosol NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Cytosol "CAB002620: " "unprognostic (8.65e-2)" "unprognostic (1.33e-1)" "unprognostic (6.40e-3)" "unprognostic (1.39e-1)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (1.18e-1)" "unprognostic (2.35e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 1.4 0.1 0.0 0.0 0.0 0.1 0.0 74.4 12.9 0.0 0.0 0.0 123.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.1 0.0 0.0 0.2 0.0 0.1 0.0 1.7 0.1 0.0 64.3 0.0 0.2 0.0 0.0 0.0 0.4 0.3 0.0 7.8 0.5 0.0 0.0 117.8 0.5 0.7 177.4 305.3 0.1 8.3 0.1 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.2 38.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MAGEB2 "CT3.2, DAM6, MAGE-XP-2, MGC26438" ENSG00000099399 "MAGE family member B2" O15479 X 30215563-30220089 "Predicted intracellular proteins" "Ubl conjugation pathway" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 60 "testis: 29.1" "Group enriched" "Detected in some" 4 "Spermatocytes: 24.7;Spermatogonia: 95.8" "Cancer enriched" "Detected in many" 7 "testis cancer: 33.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HL-60: 92.4;K-562: 66.9;Karpas-707: 77.0;U-2 OS: 89.9;U-266/70: 149.7;U-266/84: 168.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA065224, HPA074544, HPA075519" Enhanced Approved Cytosol NA Yes "Cluster 36: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Cytosol "HPA065224: AB_2685437, HPA074544: AB_2732258, HPA075519: AB_2732294" "unprognostic (4.52e-1)" "unprognostic (2.55e-2)" "unprognostic (6.39e-2)" "unprognostic (5.02e-1)" "unprognostic (6.57e-2)" "unprognostic (1.79e-2)" "unprognostic (1.00e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 6.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 92.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 66.9 77.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.2 0.0 0.5 0.0 14.8 0.2 0.0 89.9 0.3 0.3 149.7 168.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 3.1 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 24.7 95.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 MAGED1 "DLXIN-1, NRAGE" ENSG00000179222 "MAGE family member D1" Q9Y5V3 X 51803007-51902354 "Cancer-related genes, Predicted intracellular proteins" "Biological rhythms, Ubl conjugation pathway" "Tumor antigen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 335.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 534.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043645 Approved Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA043645: AB_2678597" "unprognostic (5.70e-2)" "unprognostic (1.16e-1)" "unprognostic (7.29e-2)" "unprognostic (1.39e-2)" "unprognostic (3.92e-2)" "unprognostic (1.37e-1)" "unprognostic (4.04e-3)" "unprognostic (2.04e-2)" "unprognostic (3.92e-1)" "unprognostic (1.77e-1)" "unprognostic (3.15e-3)" "unprognostic (1.42e-1)" "unprognostic (6.10e-3)" "unprognostic (2.14e-3)" "unprognostic (2.22e-1)" "prognostic unfavorable (3.25e-4)" "unprognostic (1.71e-3)" 32.4 125.4 69.8 37.7 73.1 16.7 38.0 34.7 71.1 99.7 99.2 40.0 32.4 57.3 102.4 26.6 64.7 58.8 70.2 70.7 108.8 43.0 71.5 40.4 29.2 57.4 66.2 62.5 80.2 76.8 157.0 116.2 76.3 71.7 39.6 37.1 85.3 89.0 46.8 29.9 32.3 77.6 62.0 35.4 54.6 56.5 84.7 49.0 73.7 39.1 31.6 45.4 35.5 49.7 21.3 76.2 238.5 205.8 184.3 330.4 128.1 281.2 357.7 152.5 240.0 157.3 71.0 29.9 53.6 534.9 54.4 15.6 215.5 99.6 113.2 31.8 83.1 20.3 0.4 205.7 140.9 75.8 35.8 312.2 35.0 128.6 29.1 267.7 184.8 77.1 31.5 57.6 310.5 194.8 87.7 25.4 187.6 69.4 154.3 88.4 154.2 4.1 156.7 37.4 60.9 340.1 0.0 80.6 41.9 232.0 145.6 18.8 185.6 66.1 166.5 234.7 31.8 37.5 59.5 60.3 257.9 6.9 175.1 1.5 4.4 3.1 21.1 6.0 18.7 17.2 13.7 18.5 13.2 19.4 17.1 20.5 1.3 16.3 6.1 55.8 21.1 14.3 69.8 73.1 34.7 71.1 70.7 108.8 57.4 66.2 76.3 62.0 84.7 49.7 12.2 76.9 34.5 85.8 17.1 11.5 20.4 48.1 12.5 33.2 41.9 27.9 53.4 32.9 63.8 35.0 8.4 335.2 17.1 18.6 29.4 47.9 2.5 35.6 73.4 24.5 57.1 13.9 97.5 49.9 171.5 69.5 34.7 54.3 17.7 60.7 39.7 62.5 114.6 45.4 138.5 74.4 54.9 9.2 6.8 10.0 43.2 6.3 24.9 42.2 4.9 39.7 13.4 101.6 55.0 33.5 13.5 57.6 72.6 20.2 15.9 33.2 48.3 12.5 13.1 28.2 50.0 5.7 5.9 12.4 8.2 185.7 11.9 169.9 25.2 18.8 MAP1A MAP1L ENSG00000166963 "Microtubule associated protein 1A" P78559 15 43510958-43531620 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "brain: 325.5" "Cell type enhanced" "Detected in many" "dendritic cells: 90.9;Horizontal cells: 299.5;Peritubular cells: 76.3" "Cancer enhanced" "Detected in many" "glioma: 18.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 61 "plasmacytoid DC: 10.5" "Lineage enriched" "Detected in single" 61 "dendritic cells: 10.5" "Cell line enhanced" "Detected in many" "ASC diff: 60.7;BJ hTERT+: 61.8;fHDF/TERT166: 94.0;hTEC/SVTERT24-B: 58.1;U-87 MG: 121.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039063, HPA039064, HPA066488" Enhanced Approved Cytosol No No 55000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 62: Horizontal cells - Visual perception" Cytosol "HPA039063: AB_2676327, HPA039064: AB_10673302, HPA066488: AB_2685676" "unprognostic (1.60e-1)" "unprognostic (1.31e-1)" "unprognostic (3.29e-2)" "unprognostic (1.86e-3)" "unprognostic (4.45e-2)" "unprognostic (3.58e-2)" "unprognostic (5.66e-2)" "unprognostic (1.12e-1)" "unprognostic (2.65e-2)" "unprognostic (1.13e-3)" "unprognostic (8.36e-3)" "unprognostic (3.45e-3)" "prognostic unfavorable (6.59e-5)" "unprognostic (5.83e-2)" "unprognostic (2.53e-1)" "prognostic unfavorable (1.09e-5)" "prognostic unfavorable (1.66e-5)" 7.2 6.0 65.3 3.8 78.6 0.9 4.4 39.5 325.5 8.0 0.0 16.5 1.2 8.2 2.4 3.0 7.2 4.2 15.5 92.8 37.5 1.2 0.2 2.2 1.0 201.4 41.4 5.0 1.0 2.0 11.7 2.7 186.0 4.8 3.5 21.7 2.5 7.5 4.5 3.2 4.0 13.1 22.5 0.9 4.3 3.8 85.8 24.0 4.1 5.1 0.9 11.9 4.5 156.7 0.3 2.5 11.1 6.4 60.7 41.5 0.1 36.3 61.8 10.5 10.1 4.4 0.1 0.2 15.3 94.0 3.3 0.5 15.0 0.1 6.1 5.5 1.4 14.2 3.5 0.3 5.8 0.4 5.8 31.3 0.1 58.1 0.3 15.8 8.0 41.3 24.0 0.3 42.8 0.5 26.6 0.8 8.1 0.0 1.0 7.2 32.1 0.1 0.2 0.1 34.8 10.6 1.2 0.1 0.3 14.6 2.3 0.6 1.5 33.7 11.3 11.3 0.5 0.0 1.6 5.0 121.4 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.1 0.1 65.3 78.6 39.5 325.5 92.8 37.5 201.4 41.4 186.0 22.5 85.8 156.7 6.7 3.2 1.1 11.8 2.2 5.5 1.4 1.4 2.8 43.4 1.7 3.6 55.1 0.0 7.9 3.7 25.0 0.3 90.9 1.0 0.0 0.4 13.1 33.2 19.5 5.7 11.4 3.0 34.4 0.0 0.6 46.9 2.6 1.0 7.0 16.7 4.2 0.0 2.4 299.5 45.1 1.7 10.2 0.3 7.4 5.6 51.0 9.4 8.8 12.2 0.7 16.7 0.0 9.5 51.4 0.7 0.0 76.3 1.1 0.5 0.0 0.5 63.6 27.2 32.9 45.7 48.2 10.6 25.6 1.1 4.1 1.1 5.6 3.1 1.4 0.5 MAP1B "MAP5, PPP1R102" ENSG00000131711 "Microtubule associated protein 1B" P46821 5 72107234-72209565 "Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 431.3;retina: 154.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 717.2;Excitatory neurons: 571.8;Horizontal cells: 647.8;Rod photoreceptor cells: 562.1;Sertoli cells: 769.2;Smooth muscle cells: 461.2" "Cancer enriched" "Detected in all" 5 "glioma: 48.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "TIME: 301.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009792, HPA022275" Enhanced Supported Enhanced Cytosol NA NA 180000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "CAB009792: AB_2137420, HPA022275: AB_1853944" "unprognostic (9.96e-2)" "unprognostic (3.97e-2)" "unprognostic (1.57e-2)" "unprognostic (3.70e-1)" "unprognostic (4.67e-3)" "unprognostic (2.98e-2)" "unprognostic (1.74e-1)" "unprognostic (1.73e-1)" "unprognostic (1.42e-1)" "unprognostic (7.00e-2)" "unprognostic (4.78e-3)" "unprognostic (1.32e-1)" "unprognostic (1.52e-2)" "unprognostic (1.13e-2)" "unprognostic (1.90e-1)" "unprognostic (1.75e-2)" "prognostic unfavorable (8.22e-5)" 30.2 19.4 135.6 10.9 127.6 0.1 17.8 181.9 299.9 14.9 0.0 16.9 2.1 16.6 9.5 13.0 11.5 11.0 25.8 138.9 310.5 4.0 2.2 7.1 2.2 392.1 297.1 7.0 3.6 2.5 16.4 10.0 431.3 20.1 5.3 154.9 7.7 25.4 6.0 13.3 7.1 26.4 222.4 1.3 15.3 12.0 332.9 1.5 8.3 9.6 1.3 26.7 11.4 272.0 1.4 62.8 133.5 48.7 80.9 140.1 0.2 32.6 22.7 29.0 34.5 0.5 1.7 0.1 71.8 108.2 87.9 0.6 73.2 2.8 43.3 0.2 12.3 6.7 22.3 18.3 43.6 0.0 5.1 142.1 9.3 116.7 42.8 25.9 91.6 0.2 10.6 0.3 49.5 0.6 0.1 0.0 36.5 0.0 21.3 0.4 16.4 0.1 2.5 0.1 89.9 63.0 28.9 0.3 14.9 109.7 0.2 6.1 301.6 90.7 44.6 69.4 140.3 8.0 0.4 0.2 98.5 0.1 72.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 135.6 127.6 181.9 299.9 138.9 310.5 392.1 297.1 431.3 222.4 332.9 272.0 45.6 0.0 2.0 85.5 1.5 31.6 71.3 2.3 5.2 240.3 14.3 34.3 366.0 2.8 11.5 9.2 717.2 1.6 0.6 0.0 0.0 12.9 13.2 75.4 116.8 97.8 77.6 0.0 571.8 3.4 1.4 220.6 6.6 27.7 1.3 25.3 42.1 0.8 6.4 647.8 350.7 0.7 18.3 1.3 28.4 23.4 309.7 10.1 80.0 91.8 0.0 406.1 0.0 131.2 269.3 7.1 0.0 384.8 0.5 22.1 0.1 0.9 48.6 562.1 769.2 85.4 461.2 8.9 8.0 1.9 50.6 4.0 4.2 269.9 0.2 20.0 MAP2K2 "MEK2, PRKMK2" ENSG00000126934 "Mitogen-activated protein kinase kinase 2" P36507 19 4090321-4124122 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 724.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003835, HPA051993" Supported Supported Cytosol NA NA 140000 "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB003835: AB_562312, HPA051993: AB_2681685" "unprognostic (4.39e-1)" "prognostic favorable (3.72e-4)" "unprognostic (4.24e-1)" "unprognostic (1.26e-3)" "unprognostic (2.58e-1)" "prognostic favorable (7.98e-4)" "unprognostic (2.08e-3)" "unprognostic (2.11e-1)" "unprognostic (2.65e-1)" "unprognostic (1.06e-1)" "unprognostic (7.45e-3)" "unprognostic (4.95e-2)" "unprognostic (1.32e-1)" "prognostic favorable (5.43e-5)" "unprognostic (2.91e-2)" "unprognostic (2.25e-1)" "unprognostic (4.90e-2)" 73.9 118.4 145.5 54.1 143.1 102.4 69.1 151.5 190.7 76.6 150.4 103.4 134.0 72.3 23.2 121.6 64.7 30.4 156.6 145.9 147.3 82.6 123.3 66.8 57.1 149.6 152.9 84.1 134.3 54.9 99.3 36.4 154.3 93.9 42.7 68.0 79.6 37.6 289.0 95.8 101.0 31.7 143.5 89.1 92.7 131.6 150.7 69.3 74.6 132.1 41.0 77.2 75.2 142.8 163.1 175.4 93.7 132.8 127.1 151.9 93.8 104.5 138.8 139.6 125.8 153.0 85.5 137.7 95.9 120.0 111.9 114.3 74.2 111.6 107.4 118.1 90.4 50.5 91.4 171.7 194.0 93.6 101.8 168.8 106.8 98.2 129.5 185.5 125.2 123.0 98.1 263.1 119.3 203.5 186.3 130.6 107.8 118.6 125.9 140.7 61.9 159.1 123.5 102.7 126.8 126.3 95.7 130.6 344.1 107.3 101.0 158.5 111.8 113.6 98.2 293.4 163.9 263.1 172.4 100.2 176.5 166.8 199.3 27.5 13.0 45.4 16.9 16.6 13.6 13.0 13.3 17.2 15.9 18.2 12.3 15.9 21.2 18.8 14.1 9.0 14.3 7.3 145.5 143.1 151.5 190.7 145.9 147.3 149.6 152.9 154.3 143.5 150.7 142.8 77.7 9.6 31.9 22.5 62.3 35.4 93.3 21.3 15.4 85.1 92.9 95.4 62.9 44.3 22.8 40.5 41.7 28.7 102.3 300.5 146.8 20.7 248.1 59.5 68.3 52.1 63.2 123.1 17.6 45.5 38.6 60.3 64.7 48.8 19.7 124.4 49.2 48.1 55.0 121.1 23.2 107.7 16.2 56.0 38.2 724.3 35.8 65.6 42.7 10.3 28.5 121.1 62.8 13.0 24.2 47.0 151.8 23.0 79.9 103.2 166.1 92.8 18.9 106.8 26.3 93.1 71.8 23.5 17.4 42.9 63.9 35.6 77.0 120.2 119.9 113.1 MAP3K1 "MAPKKK1, MEKK, MEKK1" ENSG00000095015 "Mitogen-activated protein kinase kinase kinase 1" Q13233 5 56815549-56896152 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 210.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SH-SY5Y: 52.5;THP-1: 51.0" "Region enriched" "Detected in all" 6 "olfactory bulb: 18.2" "Low region specificity" "Detected in all" "CAB004500, HPA046509" Approved Approved Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 57: B-cells - Immune response" Cytosol "CAB004500: AB_627926, HPA046509: AB_2679678" "unprognostic (1.77e-1)" "unprognostic (1.71e-2)" "unprognostic (4.09e-1)" "unprognostic (2.18e-1)" "unprognostic (3.48e-2)" "unprognostic (5.39e-3)" "unprognostic (5.20e-3)" "unprognostic (2.52e-2)" "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (1.05e-2)" "unprognostic (6.73e-2)" "unprognostic (1.97e-3)" "unprognostic (2.18e-2)" "unprognostic (1.58e-1)" "unprognostic (9.92e-3)" "unprognostic (1.11e-1)" 5.5 3.8 3.0 13.3 2.6 24.0 20.1 4.0 2.1 7.0 6.2 5.4 6.3 7.5 6.6 10.0 9.7 5.7 3.7 2.1 2.7 9.9 6.0 7.5 18.1 3.9 3.2 7.2 9.8 7.1 1.3 11.4 3.7 5.4 6.3 26.9 18.5 8.3 1.7 19.7 6.5 5.7 3.8 20.5 8.1 8.3 3.5 9.9 16.2 4.4 24.0 6.7 6.4 3.9 13.3 7.9 12.1 8.1 1.9 1.5 20.3 2.5 3.3 7.6 10.6 37.1 9.7 11.9 0.9 3.0 6.5 6.7 10.1 4.6 10.5 4.0 4.4 6.6 3.4 17.5 4.7 10.6 17.6 1.9 4.8 2.4 3.8 2.1 3.3 4.0 5.8 20.7 2.0 5.8 7.4 14.2 5.6 6.8 1.0 11.5 8.6 41.1 13.2 13.6 5.1 52.5 7.6 9.5 21.5 10.7 26.0 51.0 9.8 0.7 6.4 2.9 4.7 15.0 8.2 22.1 1.2 6.1 13.2 6.3 3.1 0.7 0.8 4.5 0.7 4.0 2.4 1.1 1.8 3.3 1.5 0.5 1.7 1.7 4.9 1.0 3.8 1.7 3.0 2.6 4.0 2.1 2.1 2.7 3.9 3.2 3.7 3.8 3.5 3.9 20.8 6.4 9.8 17.9 102.5 52.4 15.1 17.1 43.9 14.9 73.2 30.6 3.5 48.6 15.9 36.8 47.9 15.1 31.9 7.3 7.9 18.9 2.0 25.0 20.6 24.0 10.2 14.5 11.7 14.8 8.6 10.7 14.3 43.7 7.6 20.0 21.8 15.0 32.3 28.6 31.8 11.4 6.1 76.0 48.4 3.6 5.3 66.5 37.4 69.3 99.1 11.6 9.2 210.1 12.5 12.9 7.7 1.9 41.5 14.8 10.6 20.7 11.0 38.5 6.6 9.3 11.9 8.6 17.9 69.1 54.7 6.7 31.6 15.4 9.7 12.0 MAP3K19 "FLJ23074, RCK, YSK4" ENSG00000176601 "Mitogen-activated protein kinase kinase kinase 19" Q56UN5 2 134964485-135047468 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 5.0;choroid plexus: 9.3;fallopian tube: 18.3;testis: 5.4" "Group enriched" "Detected in some" 8 "Early spermatids: 59.7;Endometrial ciliated cells: 73.7;Late spermatids: 148.4;Respiratory ciliated cells: 121.0" "Cancer enhanced" "Detected in some" "endometrial cancer: 0.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011388 Uncertain Cytosol NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA011388: AB_1848822" "unprognostic (7.12e-3)" "unprognostic (6.55e-3)" "unprognostic (6.96e-2)" "unprognostic (3.90e-3)" "unprognostic (3.63e-1)" "unprognostic (2.21e-1)" "unprognostic (1.96e-1)" "unprognostic (9.38e-2)" "unprognostic (1.09e-1)" "unprognostic (4.33e-1)" "unprognostic (2.02e-2)" "unprognostic (1.32e-1)" "unprognostic (4.04e-6)" "unprognostic (1.50e-1)" "unprognostic (4.13e-2)" "unprognostic (1.54e-1)" "unprognostic (2.83e-4)" 0.0 0.1 1.1 0.0 1.2 0.0 0.0 0.8 0.8 0.5 9.3 0.0 0.0 0.6 0.0 0.0 18.3 0.0 0.1 1.1 1.9 0.0 0.0 1.5 0.1 5.0 3.6 0.0 0.0 0.0 0.3 0.0 3.0 0.1 0.0 0.5 0.1 0.0 0.0 0.1 0.1 0.0 3.8 0.0 0.0 5.4 1.9 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.2 0.8 0.8 1.1 1.9 5.0 3.6 3.0 3.8 1.9 3.1 0.1 0.0 1.1 2.3 0.1 0.0 0.1 2.6 0.0 0.3 0.0 0.0 0.4 0.0 11.4 0.0 10.4 0.0 0.0 0.0 0.0 0.0 59.7 73.7 0.4 0.0 0.0 0.0 1.3 0.0 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 2.0 0.0 0.0 148.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 1.0 1.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 121.0 0.2 0.0 0.0 0.8 7.5 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 MAP3K20 "MLK7, MLTK, MLTKalpha, MLTKbeta, MRK, ZAK" ENSG00000091436 "Mitogen-activated protein kinase kinase kinase 20" Q9NYL2 2 173075435-173268015 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 261.9;tongue: 279.7" "Cell type enhanced" "Detected in many" "Adipocytes: 57.5;Alveolar cells type 2: 57.7;Cytotrophoblasts: 52.6;Endometrial stromal cells: 96.7;Granulosa cells: 100.7;Smooth muscle cells: 83.2;Theca cells: 70.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 15.5" "Group enriched" "Detected in many" 5 "dendritic cells: 15.5;monocytes: 9.4" "Cell line enhanced" "Detected in many" "U-138 MG: 176.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017205 Approved Supported Cytosol NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA017205: AB_1858933" "unprognostic (2.90e-2)" "unprognostic (9.99e-3)" "unprognostic (4.63e-3)" "unprognostic (1.98e-1)" "unprognostic (7.63e-2)" "unprognostic (5.02e-2)" "unprognostic (2.34e-2)" "unprognostic (3.89e-3)" "unprognostic (2.83e-2)" "unprognostic (9.27e-2)" "unprognostic (4.54e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (3.41e-6)" "unprognostic (2.34e-1)" "unprognostic (1.86e-1)" "unprognostic (2.23e-1)" "unprognostic (1.19e-2)" 71.0 11.4 9.5 20.5 9.7 4.7 21.4 10.3 8.5 44.9 15.7 65.8 13.0 76.4 18.6 50.0 48.0 31.4 195.7 9.3 12.1 7.5 25.2 22.5 9.8 13.8 14.7 69.5 11.7 49.3 3.8 27.6 11.2 44.0 20.9 2.5 12.4 57.1 261.9 14.1 19.2 75.0 11.1 12.5 31.5 10.6 12.5 11.5 16.4 279.7 10.2 56.1 21.2 9.4 34.6 28.6 22.0 29.1 62.7 92.5 13.8 121.9 94.7 55.9 59.6 19.5 22.2 26.5 31.2 122.5 48.8 22.9 33.1 64.6 124.2 52.0 22.0 43.3 30.5 4.1 24.8 39.3 43.8 74.7 27.2 105.2 164.2 46.3 37.5 28.5 19.8 4.9 36.8 14.8 24.8 19.0 12.2 28.9 16.0 36.2 45.0 0.1 13.6 19.6 12.9 12.4 47.0 11.3 19.7 35.6 12.9 20.9 37.9 176.3 71.4 53.1 27.9 0.1 0.1 5.5 126.2 10.6 18.9 0.2 9.4 0.0 1.0 8.3 1.0 1.6 0.8 1.7 15.5 2.5 0.0 0.8 2.6 0.5 8.2 0.3 0.8 3.4 9.5 9.7 10.3 8.5 9.3 12.1 13.8 14.7 11.2 11.1 12.5 9.4 57.5 38.5 57.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 20.0 44.4 0.0 0.0 7.4 11.0 0.0 52.6 2.3 0.0 1.9 43.9 0.0 36.7 96.7 14.1 0.0 0.0 0.0 27.6 21.9 36.5 0.0 35.6 5.1 100.7 0.0 0.0 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 15.5 0.0 0.0 0.0 0.0 38.6 0.0 0.0 1.4 0.0 0.0 1.9 13.1 0.0 0.0 0.0 83.2 0.0 0.0 0.0 0.0 21.6 3.6 70.5 0.0 0.0 MAP3K4 "KIAA0213, MAPKKK4, MEKK4, MTK1" ENSG00000085511 "Mitogen-activated protein kinase kinase kinase 4" Q9Y6R4 6 160991727-161117385 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 87.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 31.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007625 Uncertain Approved Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" Cytosol "HPA007625: AB_1853770" "unprognostic (3.05e-3)" "unprognostic (2.19e-2)" "unprognostic (1.36e-1)" "unprognostic (1.44e-1)" "unprognostic (2.06e-1)" "unprognostic (7.65e-2)" "unprognostic (1.35e-3)" "unprognostic (6.38e-2)" "unprognostic (2.09e-1)" "unprognostic (3.81e-3)" "unprognostic (2.09e-2)" "unprognostic (2.61e-1)" "unprognostic (1.16e-2)" "unprognostic (5.86e-2)" "unprognostic (3.45e-1)" "unprognostic (1.93e-1)" "unprognostic (6.84e-2)" 4.9 3.9 5.1 6.4 4.4 5.8 6.0 9.4 7.7 7.8 0.0 6.0 5.3 9.3 3.6 8.5 7.2 4.5 5.5 6.4 4.8 5.0 4.5 6.2 7.3 2.7 2.0 8.6 6.4 8.0 3.9 7.1 3.6 7.3 5.3 4.1 7.3 6.3 11.1 8.5 5.5 7.6 2.7 6.3 5.8 7.5 3.1 9.6 5.5 10.2 9.8 7.1 6.7 5.6 8.1 9.0 16.8 14.7 9.9 11.9 11.1 9.0 7.9 10.2 10.7 12.6 5.8 16.7 6.4 23.2 14.6 19.7 17.4 18.0 12.4 12.4 14.3 21.8 8.5 12.9 7.9 22.9 10.1 7.6 20.5 10.7 9.6 15.8 13.5 12.4 56.1 18.8 11.0 8.3 15.6 11.9 10.3 5.8 13.8 16.9 15.6 13.3 9.0 5.8 9.7 8.5 17.0 17.8 1.5 14.7 7.4 27.6 13.0 12.4 15.9 11.7 43.3 10.8 9.3 15.3 14.6 23.2 13.2 31.5 4.0 2.7 5.2 3.2 9.3 6.7 7.5 4.8 4.9 9.1 5.2 5.2 0.2 4.1 1.9 6.1 5.7 3.0 5.1 4.4 9.4 7.7 6.4 4.8 2.7 2.0 3.6 2.7 3.1 5.6 19.9 19.2 12.2 32.7 20.8 9.8 10.5 9.7 30.7 18.5 13.3 16.8 20.9 10.0 14.9 14.7 22.9 20.6 17.0 7.1 3.9 9.7 5.5 35.3 55.4 14.5 15.4 12.8 66.1 7.5 11.5 16.1 15.8 39.4 3.8 35.3 6.1 8.3 7.3 23.5 64.5 9.3 6.1 8.2 6.4 4.4 11.5 15.3 0.0 45.9 18.8 14.9 10.3 87.4 57.1 12.5 8.1 12.4 18.2 13.6 9.3 6.9 10.6 29.8 6.6 21.8 19.4 14.7 25.7 28.1 11.8 33.1 25.2 8.1 11.7 16.7 MAP3K5 "ASK1, MAPKKK5, MEKK5" ENSG00000197442 "Mitogen-activated protein kinase kinase kinase 5" Q99683 6 136557046-136792477 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Immunity, Innate immunity, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 88.1" "Cell type enhanced" "Detected in many" "Astrocytes: 383.6;Excitatory neurons: 170.4;Inhibitory neurons: 204.8;Microglial cells: 216.4;Oligodendrocyte precursor cells: 210.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 42.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007824, HPA063245" Supported Supported Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 35: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "CAB007824: AB_598175, HPA063245: AB_2684969" "unprognostic (1.37e-1)" "unprognostic (3.21e-2)" "unprognostic (2.85e-2)" "unprognostic (1.38e-1)" "unprognostic (3.19e-1)" "prognostic favorable (6.08e-4)" "unprognostic (8.76e-2)" "unprognostic (1.41e-2)" "unprognostic (2.84e-1)" "unprognostic (1.90e-2)" "prognostic unfavorable (5.91e-4)" "unprognostic (3.97e-1)" "unprognostic (3.75e-2)" "unprognostic (1.37e-1)" "unprognostic (2.72e-1)" "unprognostic (2.72e-2)" "unprognostic (6.59e-3)" 13.2 88.1 21.7 11.7 23.6 14.1 9.5 21.6 18.9 8.4 7.0 8.7 7.3 11.3 7.7 10.0 12.9 7.5 11.3 18.6 18.9 10.6 9.0 11.9 12.1 17.2 20.7 49.3 30.9 1.9 16.2 5.3 16.1 18.0 9.7 14.5 7.1 7.1 6.3 8.0 9.0 5.1 16.6 11.7 14.8 12.0 24.8 8.2 12.8 6.1 12.3 18.5 9.2 15.7 5.6 3.4 0.0 0.0 7.6 20.2 1.9 8.0 42.6 4.0 3.8 0.3 5.6 3.3 11.5 11.1 3.0 7.6 13.6 4.1 10.5 4.6 10.6 28.9 7.6 0.0 36.3 13.6 0.1 26.8 5.3 6.3 17.9 15.4 13.6 4.1 7.3 31.2 28.7 10.9 0.3 11.6 1.3 10.9 4.5 7.6 8.9 13.2 16.2 35.3 9.7 6.4 6.6 6.3 1.8 1.4 1.4 12.0 12.0 6.7 2.1 0.4 7.5 25.3 18.0 0.0 5.3 18.6 6.0 3.5 1.8 2.1 1.5 1.4 2.9 1.1 2.5 2.2 1.5 1.5 0.2 0.8 5.2 2.3 1.4 1.5 4.6 0.9 21.7 23.6 21.6 18.9 18.6 18.9 17.2 20.7 16.1 16.6 24.8 15.7 11.9 6.4 22.0 383.6 14.3 5.0 20.5 32.0 3.4 18.2 10.0 5.0 21.2 4.3 35.1 11.0 6.2 1.0 25.9 12.3 3.9 3.0 6.4 17.3 31.4 7.7 34.8 14.9 170.4 23.1 1.1 12.1 20.9 62.5 5.7 67.7 9.7 11.2 8.0 0.0 204.8 18.2 14.2 23.5 10.2 4.2 23.6 26.6 0.0 216.4 21.7 43.3 12.3 210.1 4.2 17.8 8.7 14.3 13.5 18.8 7.2 8.3 20.5 2.6 13.1 5.3 17.9 3.4 15.5 13.1 10.1 2.7 18.5 16.2 11.2 23.4 MAP3K8 "c-COT, COT, EST, ESTF, MEKK8, Tpl-2" ENSG00000107968 "Mitogen-activated protein kinase kinase kinase 8" P41279 10 30434021-30461833 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 332.1" "Cell type enhanced" "Detected in many" "Macrophages: 225.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 44.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB005120, HPA017962" Supported Supported Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 41: Macrophages - Immune response" Cytosol "CAB005120: AB_2140669, HPA017962: AB_1853776" "unprognostic (1.91e-2)" "unprognostic (2.94e-1)" "unprognostic (3.07e-1)" "unprognostic (9.29e-2)" "unprognostic (6.73e-2)" "unprognostic (1.00e-2)" "unprognostic (1.44e-1)" "unprognostic (3.36e-2)" "unprognostic (1.41e-2)" "unprognostic (8.04e-3)" "unprognostic (8.23e-2)" "unprognostic (2.96e-1)" "prognostic unfavorable (8.76e-7)" "unprognostic (1.88e-1)" "unprognostic (1.49e-1)" "unprognostic (1.63e-2)" "unprognostic (5.98e-3)" 69.1 18.8 7.2 39.9 5.8 332.1 31.8 5.9 8.0 15.1 22.1 19.6 8.3 18.3 5.9 23.2 38.0 37.4 18.5 6.7 13.5 12.7 16.2 64.5 33.7 10.7 8.1 12.0 7.4 6.9 8.4 46.5 8.8 11.1 16.4 10.9 12.5 11.2 6.6 36.0 21.1 35.6 9.3 41.7 20.3 3.0 15.9 9.3 14.7 6.1 28.8 49.4 20.4 7.9 15.5 13.7 3.6 7.7 18.3 15.4 17.3 3.8 20.3 8.2 9.6 9.4 34.2 10.3 9.2 8.1 8.1 28.2 8.4 3.7 3.0 23.3 4.4 19.2 25.6 30.8 16.0 6.0 44.2 19.5 2.1 7.4 1.6 7.7 3.6 0.2 8.8 14.7 1.4 8.8 0.2 22.3 1.4 8.3 4.9 1.3 3.0 5.8 7.9 30.8 0.3 1.6 13.7 11.3 1.9 10.0 3.7 12.7 0.1 4.8 4.3 18.0 0.6 22.4 22.7 3.2 6.9 25.3 0.2 45.8 14.7 53.1 15.7 26.4 8.7 20.8 3.3 10.3 14.5 38.0 0.2 6.0 35.5 28.3 38.7 30.0 1.0 10.3 7.2 5.8 5.9 8.0 6.7 13.5 10.7 8.1 8.8 9.3 15.9 7.9 51.0 38.5 49.6 11.8 147.3 116.9 50.0 91.1 109.8 19.0 51.7 24.3 10.1 11.5 67.5 3.7 0.0 29.3 203.6 13.6 1.9 31.4 0.5 149.3 51.4 55.7 12.0 21.2 7.7 11.3 86.8 66.2 33.1 205.6 71.1 1.1 25.0 3.1 128.2 0.0 7.1 6.3 83.4 113.8 205.5 1.1 8.4 225.1 42.7 30.9 64.7 6.1 36.0 2.0 0.7 23.4 20.7 4.1 107.8 46.8 3.9 3.5 78.8 1.6 6.6 23.6 62.3 0.3 0.8 129.1 84.8 159.4 97.8 1.5 6.5 195.6 MAP6D1 "FLJ12748, SL21" ENSG00000180834 "MAP6 domain containing 1" Q9H9H5 3 183815922-183825594 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 102.6;choroid plexus: 24.9;skeletal muscle: 26.9" "Cell type enriched" "Detected in some" 13 "Oligodendrocytes: 101.3" "Cancer enhanced" "Detected in many" "glioma: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "T-47d: 63.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037991 Enhanced Supported Approved Cytosol NA NA "Cluster 70: Brain - Nervous system development" "Cluster 6: T47d - Mammary gland" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA037991: AB_10672503" "unprognostic (9.23e-3)" "unprognostic (2.70e-1)" "unprognostic (1.65e-1)" "unprognostic (1.27e-3)" "unprognostic (1.32e-1)" "unprognostic (3.67e-2)" "unprognostic (1.21e-1)" "unprognostic (1.13e-1)" "unprognostic (2.42e-1)" "unprognostic (1.28e-2)" "unprognostic (5.36e-2)" "prognostic unfavorable (3.37e-4)" "unprognostic (8.81e-12)" "unprognostic (1.08e-1)" "unprognostic (2.96e-3)" "unprognostic (1.86e-1)" "unprognostic (5.72e-2)" 0.8 0.9 40.9 0.3 66.1 0.2 0.9 60.3 73.2 1.1 24.9 1.3 0.7 1.0 0.9 1.4 1.1 0.4 1.8 40.9 44.5 1.2 1.2 0.7 0.7 67.1 59.1 1.1 4.7 0.4 2.2 0.3 60.4 3.4 0.3 1.0 1.2 0.7 26.9 3.6 1.0 0.4 53.0 1.3 0.7 1.3 56.3 3.6 1.0 14.3 0.4 1.0 1.2 102.6 3.5 2.1 3.6 0.7 0.9 1.2 2.8 4.2 0.8 7.3 5.3 2.5 0.1 0.3 5.4 6.1 3.6 2.7 6.9 1.6 4.5 2.3 11.8 0.5 0.0 0.0 2.3 4.5 1.5 0.5 0.6 1.7 0.8 0.4 1.7 5.5 0.5 0.0 0.7 14.8 10.0 5.8 2.2 2.0 6.7 5.0 5.7 0.0 0.4 0.0 11.7 2.1 2.9 2.2 4.4 2.5 63.9 4.2 0.8 1.8 2.5 2.7 6.1 2.4 1.6 1.4 0.6 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 40.9 66.1 60.3 73.2 40.9 44.5 67.1 59.1 60.4 53.0 56.3 102.6 0.0 0.0 0.0 4.9 0.1 1.1 0.7 0.9 0.6 2.5 0.0 0.0 2.4 0.0 0.4 0.0 2.1 0.3 0.0 0.9 0.0 0.0 3.4 0.0 0.0 0.3 2.4 0.4 7.4 0.0 0.5 0.4 1.1 0.0 0.0 0.0 0.7 0.4 0.9 1.7 3.5 0.4 4.1 0.0 0.7 2.2 0.9 0.3 0.0 0.0 0.5 0.8 1.0 7.1 101.3 0.0 0.1 0.0 0.2 2.4 0.2 0.0 0.3 1.9 0.0 1.6 0.4 2.9 2.1 1.0 1.4 0.7 0.3 0.0 0.3 0.7 MAPK6 "ERK3, HsT17250, p97MAPK, PRKM6" ENSG00000069956 "Mitogen-activated protein kinase 6" Q16659 15 51952106-52067375 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 218.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005184, HPA030262, HPA047825" Approved Supported Supported Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Cytosol "CAB005184: AB_2140298, HPA030262: AB_10601868, HPA047825: " "unprognostic (6.61e-2)" "unprognostic (1.75e-2)" "unprognostic (5.05e-2)" "unprognostic (3.40e-3)" "unprognostic (2.72e-1)" "unprognostic (5.52e-2)" "unprognostic (6.13e-2)" "unprognostic (2.32e-3)" "unprognostic (3.99e-2)" "unprognostic (8.54e-2)" "unprognostic (3.68e-2)" "unprognostic (3.90e-2)" "unprognostic (3.27e-3)" "unprognostic (2.03e-1)" "unprognostic (1.72e-1)" "unprognostic (3.07e-2)" "unprognostic (2.31e-2)" 10.9 7.0 8.6 12.1 11.1 32.4 13.9 14.5 13.3 15.3 7.6 20.3 17.5 16.4 10.9 28.0 8.2 17.5 7.7 10.5 10.5 15.2 35.3 8.8 10.8 10.5 10.8 6.2 8.3 11.0 8.0 12.6 10.6 10.1 18.7 17.9 15.3 8.7 27.7 23.1 24.5 13.7 9.7 8.3 16.9 29.3 10.6 14.5 13.9 32.9 13.6 27.3 21.3 12.0 27.1 36.0 69.1 26.7 21.1 34.3 50.5 38.0 38.0 34.2 40.1 43.3 15.9 38.9 26.0 48.9 50.0 37.5 53.8 72.4 46.5 24.0 16.8 58.0 20.3 68.9 50.4 43.9 118.6 36.8 130.0 41.5 106.8 36.4 32.7 26.1 76.5 64.3 44.2 61.3 30.8 34.4 24.7 33.6 17.2 26.8 44.5 62.3 32.8 112.3 33.8 31.9 30.7 24.6 56.5 94.9 22.6 64.3 32.9 40.7 43.9 26.8 51.4 33.2 104.4 47.5 50.4 62.9 51.2 1.7 2.5 0.7 1.9 2.3 2.3 2.5 2.8 2.2 2.3 1.3 2.6 1.9 0.3 3.6 1.5 1.0 4.3 1.9 8.6 11.1 14.5 13.3 10.5 10.5 10.5 10.8 10.6 9.7 10.6 12.0 31.3 28.9 31.5 24.5 24.2 111.9 123.8 50.6 24.5 55.6 39.3 19.3 21.9 25.8 43.1 16.5 16.7 16.9 15.9 110.2 17.6 35.2 147.5 61.3 75.7 28.8 31.0 17.1 29.1 50.1 39.5 39.2 35.7 126.4 137.9 19.3 17.9 59.6 28.0 33.7 31.0 42.9 42.7 41.8 66.6 218.1 22.7 50.5 30.2 17.8 15.7 32.3 11.3 28.6 63.7 69.1 46.5 23.7 35.3 89.0 110.6 60.3 42.9 23.8 19.7 24.7 33.9 72.7 81.0 49.6 110.7 33.1 23.0 13.9 28.6 174.0 MARK4 "FLJ90097, KIAA1860, MARKL1, Nbla00650, PAR-1D" ENSG00000007047 "Microtubule affinity regulating kinase 4" Q96L34 19 45079288-45305284 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 119.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039186 Approved Supported Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 12: NES - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Cytosol "HPA039186: AB_10796223" "unprognostic (1.64e-1)" "unprognostic (1.95e-1)" "unprognostic (1.57e-3)" "prognostic unfavorable (8.31e-8)" "unprognostic (2.02e-1)" "prognostic unfavorable (3.05e-5)" "unprognostic (1.90e-1)" "unprognostic (2.16e-2)" "unprognostic (6.26e-2)" "unprognostic (5.64e-3)" "unprognostic (1.24e-3)" "unprognostic (7.50e-2)" "unprognostic (3.80e-2)" "unprognostic (6.89e-2)" "unprognostic (7.23e-2)" "unprognostic (4.65e-2)" "unprognostic (3.02e-2)" 13.1 13.5 27.5 7.2 31.4 8.5 13.0 16.1 37.7 17.1 11.3 16.5 5.0 15.5 16.6 16.4 14.8 10.6 17.3 31.6 19.6 13.5 21.8 13.9 8.3 24.0 25.2 21.7 14.0 20.5 16.6 11.6 22.6 16.2 5.8 26.0 12.7 13.0 38.7 26.9 9.1 14.6 14.1 11.4 14.3 40.4 29.9 13.1 12.7 12.0 9.6 19.0 16.7 26.1 20.3 7.7 36.6 23.8 25.3 36.8 8.8 15.3 25.1 21.8 20.8 4.0 10.8 8.5 12.0 28.9 20.6 13.5 26.4 22.5 14.2 15.7 16.0 20.7 8.5 17.0 47.6 4.4 15.1 48.1 31.9 18.7 22.8 43.3 29.5 22.1 22.6 21.8 24.9 14.4 16.7 14.5 12.3 18.6 4.7 61.5 11.4 6.3 23.4 16.0 58.8 27.1 20.5 17.5 12.5 35.9 9.0 29.3 21.6 16.7 12.9 12.2 9.0 22.7 21.8 10.8 17.9 8.4 12.7 1.1 1.0 0.2 1.0 0.7 0.2 0.2 0.3 1.3 0.3 0.2 0.6 0.7 0.9 0.7 0.7 0.9 0.8 0.4 27.5 31.4 16.1 37.7 31.6 19.6 24.0 25.2 22.6 14.1 29.9 26.1 8.7 12.8 3.1 30.7 6.0 25.0 11.3 7.2 15.4 20.9 10.2 7.0 9.1 11.5 4.4 9.2 25.0 4.3 8.1 3.7 11.7 8.4 2.3 6.6 9.5 12.2 6.1 6.1 31.1 6.1 1.5 8.4 10.2 10.5 2.5 18.9 18.5 10.7 7.0 119.5 36.5 4.7 4.1 9.5 11.0 6.3 16.1 8.2 3.6 16.9 5.9 19.6 12.3 23.1 16.4 9.5 3.5 13.9 7.7 13.0 4.7 6.5 2.5 15.6 0.0 7.6 8.4 1.2 8.3 12.5 24.2 11.5 10.3 26.1 3.2 15.5 MARS1 "CMT2U, MARS, MetRS, SPG70" ENSG00000166986 "Methionyl-tRNA synthetase 1" P56192 12 57475445-57517569 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 11.9;Cytotrophoblasts: 29.5;Extravillous trophoblasts: 22.0;Hofbauer cells: 19.3;Syncytiotrophoblasts: 38.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 738.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004125, CAB017097" Supported Approved Enhanced Cytosol NA NA 23000 "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 24: Non-specific - Transcription regulation" Cytosol "CAB017097: , HPA004125: AB_1079312" "prognostic unfavorable (1.73e-4)" "unprognostic (2.21e-1)" "unprognostic (1.56e-1)" "unprognostic (1.09e-1)" "unprognostic (1.57e-2)" "unprognostic (4.90e-3)" "prognostic unfavorable (4.55e-7)" "unprognostic (8.47e-2)" "unprognostic (1.73e-1)" "unprognostic (4.03e-2)" "unprognostic (2.85e-2)" "unprognostic (3.77e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (1.13e-2)" "unprognostic (1.96e-1)" "unprognostic (1.13e-1)" "unprognostic (2.06e-2)" 35.9 47.2 63.1 35.9 65.2 31.6 31.5 62.0 83.6 30.8 61.6 47.6 21.5 40.7 39.0 54.3 30.1 19.3 50.5 67.5 67.5 55.7 60.6 42.7 34.5 64.2 65.5 24.2 64.4 40.7 58.9 27.3 68.1 38.7 29.6 39.6 39.6 34.0 48.5 33.0 37.3 41.3 63.5 53.9 53.2 50.7 65.6 32.6 40.0 33.1 44.4 44.8 33.6 67.9 110.6 149.6 99.7 171.9 107.1 64.6 180.2 149.0 178.4 158.1 168.6 162.9 119.0 192.3 97.6 187.2 98.3 119.4 226.0 196.4 166.2 167.4 96.9 136.7 52.8 89.4 238.1 207.7 147.5 96.2 302.9 181.5 467.5 76.6 114.8 238.1 212.9 400.3 112.1 150.4 187.9 148.1 184.8 173.0 162.3 155.5 738.3 200.0 117.0 86.4 131.6 134.0 79.8 120.9 215.8 109.6 161.0 260.7 86.9 57.5 162.8 82.8 91.6 357.5 395.8 232.5 139.7 154.8 199.1 29.9 29.8 39.3 35.1 53.6 31.7 24.4 23.4 32.0 57.9 14.7 20.0 27.4 14.5 30.0 45.6 55.9 26.3 34.2 63.1 65.2 62.0 83.6 67.5 67.5 64.2 65.5 68.1 63.5 65.6 67.9 5.8 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 29.5 7.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 22.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 38.0 1.2 0.0 0.0 0.0 MAST2 "KIAA0807, MAST205" ENSG00000086015 "Microtubule associated serine/threonine kinase 2" Q6P0Q8 1 45786987-46036122 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 170.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 66.9;Inhibitory neurons: 86.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039722, HPA040155" Approved Approved Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA039722: AB_10795294, HPA040155: AB_10793957" "unprognostic (7.80e-2)" "unprognostic (3.02e-2)" "unprognostic (5.77e-2)" "unprognostic (1.52e-1)" "unprognostic (3.82e-1)" "unprognostic (3.17e-2)" "prognostic unfavorable (4.31e-8)" "unprognostic (8.86e-2)" "unprognostic (2.34e-2)" "unprognostic (1.98e-1)" "unprognostic (1.60e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (6.85e-13)" "unprognostic (4.82e-3)" "unprognostic (2.43e-1)" "unprognostic (9.73e-2)" "unprognostic (4.90e-1)" 18.3 11.8 16.2 11.0 15.5 8.0 18.7 15.4 17.5 57.4 7.3 39.1 21.9 43.5 12.8 14.7 31.2 19.0 65.3 15.2 19.4 12.2 18.9 17.8 8.9 19.7 27.7 51.9 9.2 13.9 27.0 8.6 26.4 40.0 25.3 24.0 18.4 15.4 170.6 14.6 30.7 26.3 14.6 7.2 24.0 56.3 18.3 5.8 13.2 73.1 11.1 46.9 28.8 15.7 31.7 25.1 24.7 19.2 30.7 41.4 27.6 32.2 22.8 29.4 32.6 29.4 10.1 48.8 15.2 38.6 59.9 15.7 30.1 18.8 30.4 23.7 16.4 22.2 29.2 27.4 28.4 12.0 27.3 34.1 23.7 49.8 37.0 35.2 27.5 12.5 17.3 14.6 34.2 21.9 17.7 12.5 20.4 21.2 28.2 25.6 40.7 9.4 16.1 16.8 34.0 20.6 38.0 50.4 16.3 26.9 22.8 11.9 27.9 55.7 36.8 30.1 33.0 19.5 18.9 17.5 38.0 16.0 24.2 0.0 0.3 0.4 0.3 0.2 0.4 0.0 0.2 0.4 0.6 0.1 0.1 0.2 0.0 0.5 1.5 0.0 0.0 0.2 16.2 15.5 15.4 17.5 15.2 19.4 19.7 27.7 26.4 14.6 18.3 15.7 5.5 0.0 2.0 32.0 2.3 4.2 4.1 3.0 8.0 15.8 8.2 6.7 46.5 4.3 5.5 3.7 54.2 6.1 2.4 66.9 1.9 4.6 38.0 4.4 17.0 7.3 12.1 6.5 45.4 6.3 4.8 12.0 12.8 7.8 0.0 13.0 3.6 6.6 6.2 5.0 86.6 24.6 0.0 2.8 7.8 57.7 9.0 5.3 7.2 30.9 2.5 3.7 7.2 52.3 52.5 8.3 33.9 10.1 5.5 10.7 50.2 5.7 3.1 12.8 6.6 11.7 9.0 28.0 13.2 6.3 2.7 5.5 3.5 12.4 22.4 7.4 MB21D2 C3orf59 ENSG00000180611 "Mab-21 domain containing 2" Q8IYB1 3 192796815-192917856 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 63.8;Inhibitory neurons: 53.0;Langerhans cells: 85.0;Oligodendrocyte precursor cells: 68.9;Syncytiotrophoblasts: 110.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 4.2;T-reg: 3.9" "Lineage enriched" "Detected in single" 9 "T-cells: 4.2" "Cell line enhanced" "Detected in many" "HDLM-2: 114.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044026 Approved Approved Cytosol NA Yes "Cluster 13: T-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 44: HDLM-2 - Immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA044026: AB_10962840" "unprognostic (3.52e-2)" "unprognostic (1.02e-1)" "unprognostic (3.06e-1)" "prognostic unfavorable (3.74e-5)" "unprognostic (2.42e-2)" "prognostic unfavorable (9.94e-4)" "unprognostic (2.76e-2)" "unprognostic (3.50e-2)" "unprognostic (1.53e-1)" "unprognostic (2.46e-1)" "unprognostic (2.84e-2)" "unprognostic (1.57e-1)" "unprognostic (1.30e-3)" "unprognostic (5.94e-3)" "unprognostic (1.95e-1)" "unprognostic (3.80e-2)" "unprognostic (3.28e-2)" 3.7 4.2 2.5 3.2 2.8 1.3 3.4 3.3 3.1 2.8 1.6 3.0 8.8 5.1 1.9 2.0 3.6 4.7 4.0 2.8 2.3 4.2 1.5 3.6 1.2 2.1 2.0 4.1 1.9 2.3 3.5 13.3 1.8 1.9 2.9 2.0 1.5 1.9 2.7 4.7 9.3 5.6 1.5 2.2 3.5 7.1 1.9 1.4 1.7 1.6 1.7 8.8 2.4 2.3 26.6 3.7 6.3 19.0 3.9 5.8 11.2 18.8 17.5 33.4 19.9 17.0 4.2 0.0 11.0 46.6 13.8 11.5 14.6 4.8 36.2 114.8 8.1 3.3 1.8 2.0 7.4 0.4 1.6 7.6 7.4 9.4 5.8 2.7 6.6 3.3 0.2 1.5 5.8 19.8 0.3 0.0 13.1 14.4 45.9 0.6 10.5 5.6 7.8 15.1 9.8 5.0 4.1 12.8 1.9 12.9 19.9 0.4 2.1 6.3 18.4 11.1 36.3 48.1 41.0 0.0 4.4 4.0 8.6 0.0 0.2 0.0 0.2 0.3 1.9 0.1 4.2 1.0 0.4 0.0 2.6 0.7 0.0 0.0 0.0 0.0 3.9 0.9 2.5 2.8 3.3 3.1 2.8 2.3 2.1 2.0 1.8 1.5 1.9 2.3 2.9 6.4 0.5 16.6 1.2 9.2 0.9 2.0 1.2 10.9 4.6 3.2 1.8 1.5 3.2 0.0 2.1 63.8 0.3 2.4 0.0 6.5 0.2 12.4 2.0 7.7 10.2 0.0 28.6 0.2 9.5 5.9 1.5 15.9 0.0 5.8 9.7 0.2 5.6 8.4 53.0 2.8 4.1 3.8 85.0 1.4 3.1 10.4 14.2 17.8 13.4 1.1 0.0 68.9 30.6 2.2 6.1 6.0 4.2 0.8 15.4 9.6 2.8 1.3 13.1 3.3 4.5 1.8 16.5 1.8 8.7 110.4 3.3 5.4 3.7 2.6 MBOAT7 "BB1, hMBOA-7, LENG4, LPLAT" ENSG00000125505 "Membrane bound O-acyltransferase domain containing 7" Q96N66 19 54173412-54189882 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 108.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 9 "basophil: 157.3;eosinophil: 265.9;neutrophil: 239.1" "Lineage enriched" "Detected in all" 11 "granulocytes: 265.9" "Cell line enhanced" "Detected in many" "HMC-1: 216.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055967 Approved Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "HPA055967: AB_2682990" "unprognostic (1.89e-2)" "unprognostic (2.60e-2)" "unprognostic (2.60e-1)" "unprognostic (3.31e-1)" "unprognostic (3.54e-2)" "unprognostic (5.95e-2)" "prognostic unfavorable (5.55e-6)" "prognostic unfavorable (5.13e-4)" "unprognostic (5.36e-2)" "unprognostic (2.31e-2)" "unprognostic (1.08e-2)" "unprognostic (2.81e-1)" "prognostic unfavorable (6.62e-5)" "unprognostic (1.31e-1)" "unprognostic (4.75e-2)" "unprognostic (3.95e-1)" "prognostic favorable (4.31e-4)" 14.9 108.4 17.6 13.4 14.8 13.1 13.7 0.0 21.4 19.0 0.0 27.8 27.0 19.0 6.6 20.6 20.1 9.2 12.8 17.6 34.4 19.2 16.0 23.6 4.8 24.9 27.8 23.0 21.0 18.9 22.8 6.9 29.2 17.3 5.3 1.0 18.6 20.2 7.9 21.1 25.3 4.4 2.7 26.6 19.9 36.3 28.7 3.2 15.9 1.1 2.3 32.5 18.1 4.8 66.8 43.2 3.8 50.8 21.0 15.4 57.1 90.5 42.6 32.9 49.2 22.1 64.3 11.3 46.5 34.4 10.9 111.9 0.3 26.1 9.0 16.1 54.6 12.8 30.0 12.6 18.9 29.0 216.2 31.0 17.9 17.3 9.8 44.1 46.0 11.0 51.6 42.2 9.2 32.2 10.9 22.7 22.0 21.1 60.1 28.4 7.3 24.9 47.0 71.1 2.3 14.3 57.3 37.0 16.3 4.2 34.5 2.8 73.1 49.4 16.0 12.1 40.8 17.4 31.0 6.4 66.1 25.8 27.9 157.3 22.5 265.9 2.2 11.8 3.3 1.8 3.2 1.7 24.8 1.5 1.1 1.7 239.1 7.8 7.0 7.0 1.9 8.6 17.6 14.8 0.0 21.4 17.6 34.4 24.9 27.8 29.2 2.7 28.7 4.8 11.8 12.8 26.4 11.4 11.3 13.9 66.4 29.2 14.8 15.4 31.1 19.8 8.4 31.5 23.2 44.1 6.2 43.5 15.2 88.8 5.9 52.2 1.1 28.7 22.1 18.5 42.5 13.9 18.7 33.1 52.2 16.3 10.7 26.4 76.8 25.3 15.0 22.7 32.2 30.3 13.6 49.6 16.2 36.8 38.1 4.3 19.3 52.5 8.8 8.4 48.9 24.6 3.1 5.5 9.3 28.6 43.0 15.4 9.3 44.5 101.1 14.5 28.5 8.5 39.5 7.7 19.6 5.1 15.0 17.9 21.6 51.6 23.0 46.3 46.6 47.2 MCRIP1 "FAM195B, GRAN2, MCRIP" ENSG00000225663 "MAPK regulated corepressor interacting protein 1" C9JLW8 17 81822361-81833302 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 116.5;Exocrine glandular cells: 243.8;Extravillous trophoblasts: 154.1;Hofbauer cells: 161.7;Pancreatic endocrine cells: 137.0;Proximal tubular cells: 140.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045542 Approved Approved Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 35: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA045542: AB_2679363" "unprognostic (3.11e-3)" "unprognostic (3.82e-1)" "unprognostic (1.33e-1)" "unprognostic (3.41e-3)" "unprognostic (2.99e-1)" "unprognostic (1.21e-1)" "unprognostic (3.13e-3)" "unprognostic (2.14e-1)" "unprognostic (1.96e-1)" "unprognostic (9.08e-3)" "prognostic favorable (2.26e-4)" "unprognostic (2.53e-2)" "unprognostic (3.65e-2)" "unprognostic (4.84e-2)" "unprognostic (1.64e-1)" "unprognostic (2.87e-1)" "unprognostic (1.86e-1)" 93.2 76.0 70.1 18.7 68.1 27.4 87.6 65.7 98.5 98.8 46.6 139.6 9.1 100.8 10.4 35.6 87.3 18.3 150.1 68.0 66.0 97.7 82.6 77.6 24.1 72.8 70.8 94.5 97.6 16.8 94.1 18.1 69.7 108.6 3.7 7.3 54.6 15.6 52.2 46.3 57.3 15.9 65.5 85.1 71.5 168.4 71.6 19.9 85.5 16.5 8.0 106.0 65.2 67.0 25.8 38.0 42.8 44.8 26.7 30.1 32.8 29.7 21.1 34.8 37.8 9.9 24.8 15.6 17.3 24.6 12.7 5.8 5.1 17.0 8.6 17.1 52.5 28.0 7.1 38.4 26.2 18.7 25.4 32.7 16.4 19.7 8.5 18.9 61.3 35.5 22.7 13.0 23.1 16.8 60.2 42.4 27.0 10.2 21.5 24.0 27.4 7.1 11.9 22.7 36.0 111.7 14.9 19.5 93.2 16.3 17.9 25.0 39.8 50.1 55.0 56.0 55.3 6.8 2.3 10.8 46.6 16.6 40.5 65.7 31.8 45.4 37.8 43.2 29.2 23.7 29.6 34.0 29.4 33.8 23.7 27.3 24.9 28.3 46.3 39.9 39.5 40.3 70.1 68.1 65.7 98.5 68.0 66.0 72.8 70.8 69.7 65.5 71.6 67.0 84.9 19.2 35.0 0.0 13.1 0.0 0.0 0.0 0.0 0.0 69.4 76.6 0.0 0.0 11.2 38.6 0.0 116.5 57.9 0.0 74.3 113.5 0.0 27.5 48.5 38.9 0.0 0.0 0.0 243.8 154.1 38.3 0.0 37.7 20.2 70.7 0.0 0.0 161.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.6 0.0 0.0 49.1 0.0 0.0 0.0 0.0 137.0 0.0 0.0 6.1 0.0 0.0 140.0 13.8 0.0 0.0 0.0 54.3 0.0 0.0 0.0 0.0 98.6 23.3 50.9 0.0 0.0 METTL8 "FLJ13984, TIP" ENSG00000123600 "Methyltransferase like 8" 2 171317405-171434802 "Metabolic proteins, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 72.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035421 Uncertain Approved Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" Cytosol "HPA035421: AB_10670116" "unprognostic (3.13e-1)" "unprognostic (2.72e-1)" "unprognostic (2.92e-2)" "prognostic unfavorable (2.00e-4)" "unprognostic (1.76e-1)" "unprognostic (3.76e-1)" "unprognostic (1.43e-4)" "unprognostic (2.94e-3)" "unprognostic (7.29e-2)" "unprognostic (6.52e-3)" "unprognostic (4.83e-3)" "unprognostic (1.10e-1)" "prognostic unfavorable (6.75e-4)" "unprognostic (1.45e-1)" "unprognostic (2.04e-1)" "unprognostic (2.10e-3)" "unprognostic (2.59e-3)" 3.6 2.8 2.8 3.2 4.7 3.6 3.7 2.5 3.9 3.4 1.8 5.3 2.2 3.0 2.1 8.6 2.4 2.8 2.5 2.6 1.9 3.1 3.6 2.0 3.5 2.7 2.4 2.2 1.7 2.1 1.2 2.6 2.9 3.9 5.2 1.6 2.1 4.0 3.6 6.8 3.6 6.4 2.0 3.3 2.1 4.2 2.8 2.1 1.8 2.3 3.9 5.2 3.8 4.0 10.3 7.4 5.0 13.0 11.7 14.1 19.1 12.8 9.8 11.1 10.0 13.8 13.5 25.1 9.5 8.1 8.2 10.0 17.7 19.4 13.9 10.8 9.9 15.0 6.5 25.0 11.1 17.0 9.1 12.5 24.7 16.0 28.1 2.6 18.6 10.9 26.7 4.1 9.7 13.5 14.3 4.8 16.9 8.3 8.8 7.0 15.4 21.9 9.1 6.8 12.2 5.1 14.5 11.4 9.2 6.6 9.4 7.0 13.8 11.4 6.1 7.6 7.5 3.6 13.0 15.0 7.2 15.9 11.2 0.5 2.1 0.5 3.4 2.7 4.4 3.4 4.4 3.3 2.1 5.1 1.9 2.1 0.7 3.7 1.6 6.7 4.8 2.5 2.8 4.7 2.5 3.9 2.6 1.9 2.7 2.4 2.9 2.0 2.8 4.0 8.1 6.4 6.1 25.1 72.3 25.5 10.7 18.3 27.9 8.4 10.6 9.1 8.2 14.3 14.1 3.7 2.1 15.5 13.1 8.4 11.7 7.6 13.3 4.0 19.2 8.2 6.7 16.2 28.7 6.2 21.2 14.9 6.1 6.1 6.3 18.5 7.5 10.6 11.8 11.8 33.0 5.7 12.2 9.8 10.2 4.1 14.0 11.9 10.6 17.8 11.4 6.3 7.2 29.1 48.2 8.8 5.3 16.1 24.2 20.4 9.8 18.3 6.4 9.2 6.6 10.8 10.8 11.8 21.3 32.8 26.7 12.9 18.3 23.0 13.7 10.0 MEX3A "RKHD4, RNF162" ENSG00000254726 "Mex-3 RNA binding family member A" A1L020 1 156072013-156082465 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 4.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 16.5;Breast glandular cells: 20.8;Breast myoepithelial cells: 20.2;Granulosa cells: 26.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 60.4;NTERA-2: 55.7;SCLC-21H: 57.4;SH-SY5Y: 105.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA062703 Supported Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA062703: AB_2684840" "unprognostic (8.63e-2)" "unprognostic (2.28e-1)" "unprognostic (1.39e-1)" "unprognostic (2.55e-3)" "unprognostic (6.18e-2)" "unprognostic (2.71e-2)" "prognostic unfavorable (9.23e-8)" "unprognostic (4.25e-2)" "unprognostic (1.79e-1)" "unprognostic (2.09e-2)" "unprognostic (1.01e-1)" "unprognostic (1.96e-1)" "unprognostic (1.08e-3)" "unprognostic (4.73e-2)" "unprognostic (3.21e-2)" "unprognostic (1.75e-1)" "unprognostic (4.96e-2)" 0.3 0.1 0.9 0.5 0.8 0.4 1.2 1.1 0.8 2.2 0.3 0.4 0.4 3.2 0.3 0.7 0.8 0.5 0.2 0.8 0.8 0.8 1.0 0.4 0.2 1.1 0.8 4.4 0.4 0.3 0.2 0.3 0.8 0.8 0.4 1.0 1.1 0.3 0.0 0.5 0.3 0.8 1.1 0.2 0.3 0.5 1.0 0.9 0.4 0.0 0.3 0.8 0.8 1.0 1.1 1.9 60.4 15.2 0.7 0.9 7.3 1.5 0.3 2.5 2.2 3.7 0.9 2.0 7.3 0.7 1.5 1.3 26.5 1.2 2.9 3.2 7.4 1.5 3.2 6.3 1.2 0.9 1.3 1.8 2.0 1.2 1.0 6.2 11.7 14.2 14.9 0.2 3.5 4.2 7.4 1.2 55.7 2.6 8.1 23.6 4.9 0.4 2.1 2.9 57.4 105.2 1.8 6.9 3.7 25.2 12.0 4.7 4.2 3.8 9.4 1.1 3.7 1.4 1.0 3.4 0.4 1.9 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.8 1.1 0.8 0.8 0.8 1.1 0.8 0.8 1.1 1.0 1.0 3.6 0.0 0.5 0.0 0.8 4.0 2.4 3.7 16.5 1.7 20.8 20.2 1.0 0.0 1.7 0.0 10.4 0.8 1.4 0.6 1.9 11.8 0.2 4.3 13.3 7.6 6.0 3.8 0.2 1.5 2.2 4.1 1.1 7.7 0.0 26.8 8.6 6.7 2.2 3.3 0.6 1.8 10.2 1.0 1.5 0.4 5.0 1.2 5.4 0.0 0.0 1.4 0.0 5.5 0.7 3.5 0.2 1.2 0.4 8.3 0.0 11.9 4.3 3.1 0.0 3.4 12.5 0.3 4.3 6.0 3.4 0.3 1.2 4.3 2.5 1.9 MFGE8 "BA46, EDIL1, hP47, HsT19888, MFG-E8, OAcGD3S, SED1, SPAG10" ENSG00000140545 "Milk fat globule EGF and factor V/VIII domain containing" Q08431 15 88898683-88913381 "Cancer-related genes, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Fertilization" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 407.0;Cone photoreceptor cells: 385.7;Rod photoreceptor cells: 978.7;Sertoli cells: 1084.7;Smooth muscle cells: 476.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 14.9" "Group enriched" "Detected in many" 8 "granulocytes: 5.3;NK-cells: 7.7;T-cells: 14.9" "Cell line enhanced" "Detected in many" "ASC diff: 1784.6;ASC TERT1: 918.2;fHDF/TERT166: 660.4;HSkMC: 935.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002753, HPA002807" Enhanced Approved Cytosol "Secreted to blood" NA NA 2830000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" Cytosol "CAB002753: , HPA002807: AB_1078072" "unprognostic (1.28e-1)" "unprognostic (1.23e-1)" "unprognostic (1.63e-2)" "unprognostic (7.68e-2)" "unprognostic (2.75e-1)" "unprognostic (1.12e-1)" "unprognostic (2.32e-1)" "unprognostic (1.42e-1)" "unprognostic (8.11e-3)" "unprognostic (6.27e-2)" "unprognostic (8.49e-2)" "unprognostic (3.99e-1)" "prognostic unfavorable (6.06e-9)" "prognostic unfavorable (3.08e-4)" "unprognostic (4.85e-2)" "unprognostic (7.36e-3)" "unprognostic (2.41e-3)" 237.2 95.2 44.2 45.2 49.6 3.7 226.7 56.4 61.8 272.8 52.4 113.7 21.2 444.7 77.0 67.6 361.8 120.2 485.8 41.6 47.2 69.0 15.6 137.2 47.4 55.9 47.4 228.5 36.5 18.9 49.3 79.6 55.6 129.3 29.3 68.7 97.1 195.8 264.3 118.9 106.9 162.7 47.0 40.7 124.9 38.3 46.5 18.8 90.6 124.1 36.9 163.6 223.4 55.6 19.7 85.4 78.7 98.7 1784.6 918.2 6.9 482.7 142.4 95.4 110.3 90.5 23.5 0.0 147.5 660.4 144.6 10.2 27.6 95.8 31.1 82.3 64.7 138.1 4.6 10.2 469.8 0.2 50.1 935.7 251.8 73.5 122.5 205.3 37.0 35.3 23.4 41.1 185.1 6.2 22.6 3.2 405.4 8.3 38.4 22.7 74.4 26.4 32.6 7.3 8.2 42.9 28.0 2.5 226.1 165.6 2.4 11.1 42.0 233.2 127.8 62.3 36.3 145.3 30.5 15.9 31.6 12.2 91.5 5.3 0.2 0.4 1.3 0.0 4.2 1.2 4.2 2.9 0.0 0.9 4.3 3.3 0.0 7.7 0.1 0.1 14.9 2.1 44.2 49.6 56.4 61.8 41.6 47.2 55.9 47.4 55.6 47.0 46.5 55.6 72.1 12.8 5.4 39.2 4.0 48.7 32.2 116.3 24.5 22.1 407.0 190.4 92.8 8.6 25.5 3.7 385.7 4.5 13.1 1.6 0.0 15.7 11.0 33.3 202.2 66.9 44.8 3.8 5.1 4.3 18.6 220.0 12.8 29.7 5.1 30.1 22.1 15.5 8.1 16.8 0.4 6.4 36.7 32.9 39.7 27.9 187.0 12.9 119.2 15.0 1.8 75.9 9.2 5.5 9.6 28.3 0.2 109.1 8.8 15.8 0.1 0.2 8.3 978.7 1084.7 51.8 476.0 3.3 9.0 21.7 35.9 5.3 12.5 25.8 2.0 10.2 MIPOL1 CCDC193 ENSG00000151338 "Mirror-image polydactyly 1" Q8TD10 14 37197913-37552361 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 138.2;Excitatory neurons: 159.4;Inhibitory neurons: 141.1;Late spermatids: 129.2;Oligodendrocyte precursor cells: 91.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 25.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002893, HPA050179" Enhanced Approved Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA002893: AB_1079386, HPA050179: AB_2681043" "unprognostic (3.24e-1)" "unprognostic (1.33e-1)" "unprognostic (2.26e-1)" "unprognostic (4.30e-2)" "unprognostic (1.08e-1)" "unprognostic (6.29e-2)" "unprognostic (4.61e-4)" "unprognostic (2.37e-2)" "unprognostic (2.84e-2)" "unprognostic (2.39e-2)" "unprognostic (3.54e-2)" "unprognostic (8.73e-2)" "unprognostic (1.58e-1)" "unprognostic (3.17e-1)" "unprognostic (9.78e-3)" "unprognostic (3.41e-3)" "unprognostic (1.85e-2)" 2.5 2.7 1.8 1.2 1.6 0.4 4.0 1.0 1.6 4.7 1.8 2.7 1.3 4.4 2.2 3.4 3.4 3.3 2.8 1.4 1.7 4.0 1.9 2.4 0.3 1.9 1.7 6.2 4.5 6.5 2.8 1.4 1.8 5.5 2.1 2.9 3.4 3.3 2.0 1.8 1.2 3.5 1.8 1.2 3.5 7.9 1.8 0.9 5.3 2.8 0.6 3.4 3.5 1.9 5.3 2.2 0.8 7.4 5.3 8.7 0.0 4.8 3.2 4.0 5.9 2.9 3.2 0.0 4.6 4.0 1.6 6.1 0.0 6.6 5.4 0.0 7.8 0.0 3.6 12.8 3.4 0.0 0.1 5.5 6.6 1.1 12.8 4.9 25.2 0.0 10.5 0.1 6.0 5.3 0.0 0.0 3.1 3.5 16.3 0.0 0.7 0.0 5.8 5.9 6.2 0.0 6.2 5.3 5.5 5.4 6.6 0.0 13.4 0.0 3.9 0.0 5.5 0.0 0.0 0.0 0.0 0.0 9.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 1.8 1.6 1.0 1.6 1.4 1.7 1.9 1.7 1.8 1.8 1.8 1.9 7.9 76.9 59.2 41.4 1.2 4.2 15.7 5.8 18.2 13.8 8.0 6.6 14.3 11.5 55.8 9.2 52.1 0.1 0.7 1.6 9.8 4.9 138.2 5.6 13.8 10.4 9.1 1.3 159.4 7.4 0.1 16.2 14.3 6.0 46.7 10.8 3.9 3.0 0.1 11.8 141.1 1.9 6.1 1.6 5.7 129.2 8.4 5.2 7.2 45.0 0.2 6.0 1.0 91.0 24.9 11.3 0.8 9.1 0.1 16.2 0.9 4.0 70.0 23.0 0.0 19.9 16.7 36.2 15.1 6.3 6.3 0.0 4.7 16.2 3.5 8.6 MLC1 "KIAA0027, LVM, MLC, VL" ENSG00000100427 "Modulator of VRAC current 1" Q15049 22 50059391-50085426 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 262.7;choroid plexus: 145.6" "Cell type enriched" "Detected in some" 6 "Astrocytes: 115.6" "Cancer enriched" "Detected in some" 69 "glioma: 122.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 20.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HL-60: 228.2;NB-4: 219.8;THP-1: 401.5;U-266/70: 131.6;U-266/84: 120.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003040 Enhanced Supported Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol "HPA003040: AB_1079387" "unprognostic (2.68e-2)" "unprognostic (5.46e-6)" "unprognostic (5.41e-3)" "unprognostic (1.51e-1)" "unprognostic (1.47e-1)" "unprognostic (2.42e-3)" "unprognostic (9.54e-3)" "unprognostic (7.21e-2)" "unprognostic (2.24e-1)" "unprognostic (1.90e-1)" "unprognostic (1.31e-1)" "unprognostic (1.51e-3)" "unprognostic (8.39e-4)" "unprognostic (1.40e-1)" "unprognostic (1.55e-1)" "unprognostic (3.66e-2)" "unprognostic (2.92e-1)" 0.3 0.1 239.3 0.7 235.7 36.4 0.1 212.7 261.8 3.0 145.6 0.1 0.4 0.3 1.0 0.1 1.8 1.0 0.6 225.8 234.5 0.1 0.4 1.6 0.3 262.7 243.1 0.3 0.1 0.0 1.1 2.3 221.8 4.8 0.0 4.1 0.1 1.4 0.1 1.0 0.1 0.2 231.9 2.2 0.2 3.8 231.5 0.5 0.1 0.0 0.5 0.4 11.9 217.2 0.4 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 68.1 0.0 0.0 0.1 228.2 68.4 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 1.8 219.8 0.3 0.0 0.1 24.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 401.5 0.0 0.0 0.2 0.1 0.3 131.6 120.2 0.4 0.3 35.7 2.2 0.0 1.1 0.0 3.9 6.8 0.1 0.1 0.3 1.6 0.9 0.0 0.1 1.8 0.1 20.2 9.2 0.2 0.1 4.0 239.3 235.7 212.7 261.8 225.8 234.5 262.7 243.1 221.8 231.9 231.5 217.2 0.0 0.0 0.5 115.6 0.3 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.6 0.0 0.0 0.1 17.2 0.0 0.0 0.0 1.1 0.1 0.4 0.1 0.0 7.8 0.4 0.0 0.1 2.4 0.0 0.1 1.3 4.4 0.4 0.0 3.5 0.0 0.5 0.0 0.0 0.3 0.0 0.7 0.0 0.6 1.8 7.5 0.6 16.3 18.6 0.5 0.8 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.1 0.3 0.4 0.0 0.0 0.3 2.7 0.1 0.0 0.0 MMAA cblA ENSG00000151611 "Metabolism of cobalamin associated A" Q8IVH4 4 145599042-145660033 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Chaperone, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 24.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037361, HPA058187" Supported Supported Cytosol No No "Cluster 27: Non-specific - Gene expression" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA037361: AB_10672107, HPA058187: " "unprognostic (1.20e-1)" "unprognostic (5.07e-2)" "prognostic favorable (3.38e-4)" "unprognostic (1.97e-3)" "unprognostic (1.44e-1)" "unprognostic (4.83e-3)" "unprognostic (1.31e-3)" "unprognostic (3.98e-1)" "unprognostic (7.03e-2)" "unprognostic (7.26e-2)" "unprognostic (3.19e-3)" "unprognostic (1.46e-1)" "prognostic favorable (2.23e-5)" "unprognostic (3.40e-2)" "unprognostic (1.45e-1)" "unprognostic (1.14e-1)" "prognostic favorable (3.21e-4)" 4.1 3.2 1.4 3.0 1.9 1.7 4.2 2.7 2.3 3.0 1.3 5.8 7.4 2.4 4.0 4.1 2.7 3.8 3.3 1.5 1.4 7.3 24.5 3.7 3.1 1.3 1.5 2.3 2.0 4.2 0.7 2.8 1.3 2.3 5.3 1.9 3.5 2.8 4.7 3.8 6.2 2.6 1.2 3.5 3.6 4.5 1.3 5.2 3.1 6.0 3.7 4.7 0.8 1.6 2.5 1.4 4.0 2.1 8.4 9.8 1.1 7.1 4.0 2.3 1.4 1.7 4.3 12.1 2.1 4.4 1.1 2.2 2.0 4.4 1.7 7.5 0.8 4.0 1.3 1.5 6.5 5.6 3.3 5.5 6.1 2.6 5.8 3.7 7.2 8.1 1.1 4.6 5.1 3.4 7.2 1.4 1.5 6.2 2.7 3.7 2.2 1.4 13.3 1.3 1.9 1.4 3.5 6.0 3.3 2.4 3.9 1.5 7.0 2.8 1.4 5.0 1.6 2.2 2.0 3.3 4.4 5.5 2.8 3.9 3.1 3.0 4.5 6.1 4.0 3.1 5.3 4.6 3.2 2.6 4.0 5.3 0.5 4.8 7.4 3.3 5.2 2.3 1.4 1.9 2.7 2.3 1.5 1.4 1.3 1.5 1.3 1.2 1.3 1.6 3.6 12.8 5.6 5.5 3.6 2.9 10.4 7.7 5.7 3.4 3.0 2.4 7.6 14.3 13.0 11.0 2.1 7.9 6.5 7.7 15.6 11.1 10.5 5.0 4.5 4.1 2.4 1.7 5.7 12.5 2.8 4.8 7.1 5.7 8.2 3.4 7.9 31.8 4.9 0.0 5.7 6.5 8.2 4.1 1.6 6.3 4.7 3.6 1.8 3.7 5.6 2.3 9.2 8.0 7.4 8.4 7.3 3.0 2.8 6.5 10.9 21.1 6.8 1.6 0.0 4.2 3.8 8.7 5.2 4.4 1.1 7.7 4.5 5.7 6.7 12.2 MMP9 CLG4B ENSG00000100985 "Matrix metallopeptidase 9" P14780 20 46008908-46016561 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "bone marrow: 376.0;lymphoid tissue: 105.3" "Group enriched" "Detected in many" 5 "Hofbauer cells: 260.1;Langerhans cells: 606.0;Macrophages: 230.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebral cortex: 3.1;thalamus: 4.8" "Immune cell enriched" "Detected in some" 127 "neutrophil: 272.2" "Lineage enriched" "Detected in single" 341 "granulocytes: 272.2" "Cell line enriched" "Detected in some" 13 "NB-4: 360.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000348, HPA001238, HPA063909, CAB068199, CAB068200, CAB068201" Enhanced Approved Cytosol "Secreted to blood" NA NA 43300000 61000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB000348: , CAB068199: AB_2665675, CAB068200: AB_2665676, CAB068201: AB_2665677, HPA001238: AB_1079398, HPA063909: AB_2685150" "unprognostic (4.62e-2)" "unprognostic (1.64e-1)" "unprognostic (2.85e-2)" "prognostic favorable (2.55e-4)" "unprognostic (6.65e-3)" "unprognostic (2.82e-1)" "prognostic unfavorable (7.19e-4)" "unprognostic (1.54e-1)" "unprognostic (8.57e-2)" "unprognostic (3.21e-2)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (4.05e-5)" "unprognostic (4.65e-1)" "unprognostic (9.85e-3)" "unprognostic (2.48e-2)" "unprognostic (2.17e-3)" 19.5 0.6 0.5 61.9 0.8 376.0 8.2 0.4 3.1 2.9 0.8 5.7 11.6 1.0 0.0 2.2 2.2 3.0 3.2 0.3 0.9 2.6 3.8 21.1 103.2 0.8 0.5 0.8 1.6 0.1 1.1 2.0 0.7 1.9 3.4 0.6 3.6 0.4 0.7 3.2 12.4 1.9 0.4 105.3 11.3 1.3 4.8 17.0 2.1 0.9 36.5 12.0 1.1 0.2 0.2 0.4 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.3 0.3 28.8 0.0 0.3 0.4 0.0 1.4 0.0 0.3 0.5 0.1 0.0 0.0 0.0 0.6 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 4.0 0.0 360.6 0.8 0.0 0.2 0.4 0.3 0.1 0.0 0.0 0.6 0.6 0.0 0.6 0.0 3.7 0.3 1.2 0.3 10.3 10.9 0.1 0.3 0.3 0.2 0.2 0.1 0.8 0.2 0.0 0.7 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 272.2 0.0 0.3 0.0 0.0 0.5 0.5 0.8 0.4 3.1 0.3 0.9 0.8 0.5 0.7 0.4 4.8 0.2 0.7 0.0 5.5 0.0 3.9 34.3 0.1 61.5 0.0 3.8 0.5 2.0 0.4 1.5 0.9 0.0 8.4 1.5 2.0 0.0 0.0 0.8 0.9 0.0 0.1 7.2 0.0 0.0 0.1 1.8 2.4 2.5 0.0 0.1 1.3 0.2 0.0 0.0 260.1 3.3 0.2 0.5 0.0 1.3 606.0 0.3 0.0 230.6 56.9 0.0 2.3 1.2 0.0 0.0 0.0 1.8 0.0 0.0 0.9 0.1 0.0 0.3 6.9 5.3 0.0 0.2 45.5 6.7 11.2 0.2 28.1 1.9 3.4 0.3 0.0 0.1 MOCS1 MOCOD ENSG00000124615 "Molybdenum cofactor synthesis 1" Q9NZB8 6 39899578-39934551 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 33.7;Hepatocytes: 36.2;Sertoli cells: 78.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 40.4;JURKAT: 51.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045783, HPA058177, HPA075505" Uncertain Enhanced Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA045783: AB_10960058, HPA058177: AB_2683629, HPA075505: AB_2686751" "unprognostic (1.22e-1)" "prognostic unfavorable (1.07e-5)" "unprognostic (3.26e-2)" "unprognostic (1.44e-1)" "unprognostic (9.03e-2)" "unprognostic (1.99e-1)" "unprognostic (2.61e-2)" "unprognostic (4.85e-2)" "unprognostic (3.14e-2)" "unprognostic (1.08e-1)" "prognostic favorable (6.07e-5)" "unprognostic (5.34e-3)" "unprognostic (1.21e-1)" "unprognostic (3.97e-3)" "unprognostic (2.78e-1)" "unprognostic (2.93e-1)" "unprognostic (6.21e-2)" 33.7 9.5 14.6 3.2 17.9 0.0 26.8 16.8 14.7 8.8 11.2 11.7 16.2 10.0 10.1 6.7 10.3 5.5 22.0 12.7 16.0 20.4 40.3 22.9 4.5 17.4 18.8 9.0 11.9 9.6 5.3 35.6 16.2 5.3 5.6 3.0 6.1 7.5 25.7 7.3 12.7 9.2 15.6 2.6 7.6 3.2 17.3 3.3 16.0 45.0 3.4 10.0 6.6 16.4 0.0 2.1 7.0 11.4 19.3 7.2 15.2 8.7 15.0 12.1 10.0 40.4 0.1 0.0 8.4 7.4 7.0 0.4 8.2 9.8 8.7 0.0 8.6 0.0 0.0 13.7 12.2 0.0 3.1 12.0 3.7 7.9 4.2 7.2 10.1 51.1 8.4 0.7 11.7 5.0 16.0 0.0 7.9 0.1 4.6 0.0 6.3 1.1 7.6 8.2 6.1 8.5 0.0 4.2 7.0 6.3 5.2 1.4 16.2 12.2 9.8 7.7 4.1 0.0 1.7 0.0 1.3 0.0 4.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.5 0.0 0.3 0.0 0.0 0.0 0.2 14.6 17.9 16.8 14.7 12.7 16.0 17.4 18.8 16.2 15.6 17.3 16.4 5.7 6.4 1.5 6.2 0.1 0.6 0.6 0.7 1.2 1.6 9.3 6.5 11.6 8.6 0.3 9.2 12.5 33.7 0.5 3.6 5.9 4.4 0.8 0.9 1.6 3.3 0.0 0.0 3.2 4.1 2.3 4.3 1.1 1.4 1.3 6.3 3.3 36.2 2.9 3.3 2.6 3.5 0.0 2.8 1.0 1.8 3.7 0.4 1.8 2.8 0.0 4.6 0.0 1.0 4.4 1.0 9.1 3.0 1.3 0.2 13.2 17.8 0.0 2.2 78.9 3.9 20.3 1.6 1.9 1.2 1.1 6.2 0.3 0.8 5.5 0.6 MON1A "MGC13272, SAND1" ENSG00000164077 "MON1 homolog A, secretory trafficking associated" Q86VX9 3 49907160-49930173 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 33.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053752, HPA058032" Uncertain Approved Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 45: Intestine - Brush border" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA053752: AB_2682250, HPA058032: AB_2683584" "unprognostic (1.81e-2)" "unprognostic (6.34e-2)" "unprognostic (1.48e-1)" "unprognostic (1.14e-2)" "unprognostic (1.26e-2)" "unprognostic (3.51e-2)" "unprognostic (3.29e-2)" "unprognostic (2.34e-2)" "unprognostic (2.28e-1)" "unprognostic (2.13e-2)" "prognostic favorable (3.30e-4)" "unprognostic (5.23e-2)" "unprognostic (2.07e-1)" "unprognostic (1.46e-1)" "unprognostic (1.03e-1)" "unprognostic (3.86e-2)" "unprognostic (1.55e-1)" 6.2 8.2 15.1 3.1 15.4 2.1 5.5 12.9 18.1 6.1 9.7 10.0 15.2 7.1 1.3 7.7 4.4 1.9 8.8 14.8 13.7 7.6 11.8 5.3 2.7 13.7 14.1 4.7 7.1 3.1 9.5 2.3 14.2 6.8 1.7 1.6 4.8 3.0 14.6 6.7 9.8 2.8 13.3 5.4 7.0 13.7 14.0 3.8 7.7 5.3 2.1 7.9 6.2 14.3 5.7 4.7 2.8 8.9 8.9 5.2 4.0 8.0 3.9 7.6 8.5 7.0 3.7 17.4 7.2 7.5 6.6 7.1 6.2 10.1 3.2 14.5 15.6 7.6 5.5 9.2 11.0 8.9 10.5 7.3 10.8 14.8 5.1 3.9 11.1 7.3 11.9 5.9 5.8 9.4 10.2 13.1 6.4 12.4 23.9 6.3 3.2 13.4 5.4 4.1 8.1 5.0 3.4 6.6 8.4 1.9 5.1 6.0 8.9 5.0 6.0 14.0 13.0 12.3 13.2 10.7 7.7 13.7 7.6 0.2 8.0 4.3 13.8 6.2 15.9 12.2 11.6 14.3 9.8 5.2 14.1 11.6 2.5 17.7 5.2 4.9 13.1 10.4 15.1 15.4 12.9 18.1 14.8 13.7 13.7 14.1 14.2 13.3 14.0 14.3 8.8 3.2 5.4 5.2 3.5 14.9 2.5 6.1 9.1 3.3 4.5 3.6 7.3 1.5 4.2 1.8 4.2 4.6 5.0 5.9 1.9 4.8 14.9 2.5 3.8 6.1 6.7 7.8 5.1 6.7 3.3 3.9 8.2 2.1 4.5 2.8 4.6 14.3 5.4 0.0 5.1 5.6 6.1 3.5 4.2 33.4 3.4 2.4 5.4 1.9 3.0 4.5 7.2 4.5 4.2 12.9 5.9 5.7 8.1 6.0 15.9 13.1 3.6 2.9 0.0 4.5 7.3 16.2 7.2 11.1 9.1 4.0 6.1 6.5 7.1 2.6 MON1B "HSRG1, KIAA0872, SAND2" ENSG00000103111 "MON1 homolog B, secretory trafficking associated" Q7L1V2 16 77190835-77202398 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046285 Approved Approved Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA046285: AB_10959467" "unprognostic (1.73e-2)" "unprognostic (9.99e-2)" "unprognostic (9.97e-2)" "prognostic favorable (6.90e-4)" "unprognostic (1.94e-1)" "unprognostic (7.72e-2)" "unprognostic (5.64e-3)" "unprognostic (3.71e-2)" "unprognostic (9.78e-2)" "unprognostic (2.42e-2)" "unprognostic (1.76e-1)" "unprognostic (1.19e-1)" "prognostic favorable (9.42e-5)" "unprognostic (2.21e-2)" "unprognostic (3.62e-2)" "unprognostic (8.34e-3)" "unprognostic (1.75e-1)" 12.9 9.6 19.3 17.2 25.5 15.7 9.0 20.8 18.9 11.1 9.4 15.6 16.3 10.6 12.0 13.2 10.8 13.2 10.5 18.1 19.1 10.6 12.4 12.6 18.3 24.9 24.0 8.8 13.7 17.5 8.3 8.1 21.2 19.7 13.1 21.0 13.9 10.2 11.4 13.6 16.0 9.7 20.6 15.2 13.7 5.6 22.6 15.3 19.7 7.7 15.5 11.8 7.1 23.0 14.8 35.7 15.0 15.5 16.0 15.9 20.5 14.6 17.4 13.0 13.9 20.9 22.4 26.9 24.1 11.9 23.3 29.8 15.7 14.5 11.5 19.6 17.9 19.0 12.7 20.5 22.4 20.9 52.5 15.7 28.5 19.3 17.2 14.0 24.5 24.7 25.6 9.0 11.3 29.9 26.3 24.6 15.5 19.9 9.6 34.0 10.3 30.4 14.9 11.9 22.4 18.8 25.5 10.2 17.6 10.7 23.3 30.6 26.2 16.2 18.5 18.4 13.0 30.0 21.4 72.9 28.7 21.4 20.3 17.8 9.7 16.6 9.5 16.3 9.8 6.0 7.6 8.8 8.3 7.0 5.6 7.2 21.7 10.3 11.1 4.7 9.9 9.0 19.3 25.5 20.8 18.9 18.1 19.1 24.9 24.0 21.2 20.6 22.6 23.0 19.4 38.5 34.8 1.6 17.3 7.5 10.0 12.7 8.0 15.0 16.6 14.4 12.6 12.8 19.8 14.7 18.8 10.5 16.9 42.3 3.9 14.0 17.8 13.1 15.6 20.7 24.0 16.2 1.9 19.5 12.4 12.6 21.9 20.0 12.7 17.4 19.6 28.4 13.2 8.4 3.0 27.9 10.2 32.0 7.8 14.1 9.0 18.7 8.8 4.7 26.1 21.5 26.8 3.0 5.0 20.0 18.7 10.1 13.8 21.0 23.8 11.7 14.6 23.5 19.7 21.6 11.0 10.4 5.3 14.6 9.5 16.8 17.2 10.9 23.5 18.8 MOV10 "fSAP113, gb110, MGC2948" ENSG00000155363 "Mov10 RISC complex RNA helicase" Q9HCE1 1 112673141-112700746 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, RNA-mediated gene silencing, Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 54.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA031627 Approved Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA031627: AB_2673966" "unprognostic (1.44e-2)" "unprognostic (1.83e-2)" "unprognostic (1.53e-1)" "unprognostic (6.82e-3)" "unprognostic (1.91e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (3.44e-4)" "unprognostic (9.89e-2)" "unprognostic (1.54e-1)" "unprognostic (1.58e-3)" "unprognostic (2.85e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (1.48e-11)" "unprognostic (4.01e-2)" "unprognostic (3.61e-1)" "unprognostic (1.46e-3)" "unprognostic (1.21e-3)" 7.6 13.2 3.4 9.7 3.7 4.7 7.6 2.9 3.4 10.2 4.7 10.9 22.1 10.2 9.5 13.2 13.5 9.4 5.2 3.1 6.2 10.3 19.4 9.1 8.5 4.7 4.1 9.7 8.2 12.8 11.2 23.6 4.0 11.5 10.7 3.0 14.3 11.2 3.1 27.2 20.2 10.8 4.1 12.1 10.7 16.6 5.4 16.2 9.8 4.2 7.0 9.3 10.8 3.4 29.5 17.9 10.4 40.2 8.3 23.5 39.1 19.8 46.5 56.9 80.7 33.2 31.7 0.0 13.2 27.4 21.1 30.5 39.7 47.4 19.6 32.4 24.2 20.2 26.7 37.8 35.3 8.5 19.3 39.9 14.2 34.6 10.9 37.4 49.2 40.7 27.2 9.8 17.8 54.7 32.7 6.6 23.4 12.2 18.1 57.9 26.2 1.3 26.4 31.9 4.4 15.0 40.9 27.5 31.5 20.2 21.4 19.4 29.7 17.6 31.0 12.4 17.8 11.3 3.3 0.1 34.9 17.4 51.4 0.9 3.5 0.7 12.5 10.3 12.4 2.1 10.8 11.1 6.8 1.5 10.3 8.0 1.1 12.7 12.2 1.0 10.2 7.6 3.4 3.7 2.9 3.4 3.1 6.2 4.7 4.1 4.0 4.1 5.4 3.4 13.0 9.6 10.5 26.4 6.3 8.8 10.4 15.5 8.0 2.4 7.8 7.0 4.1 8.6 17.4 16.5 0.0 54.7 5.6 29.2 3.9 15.5 5.9 5.8 7.3 16.9 15.0 3.8 4.1 15.5 18.4 9.4 23.9 7.0 1.3 36.5 16.8 18.3 15.8 5.0 2.3 18.0 12.2 7.5 6.0 6.2 9.3 10.3 3.6 12.2 14.4 15.1 10.3 18.1 3.3 12.4 26.9 7.5 3.6 11.1 46.2 13.9 18.4 1.1 13.1 4.0 7.4 2.7 3.4 11.7 7.0 38.2 9.2 22.4 15.5 12.1 MOXD1 "dJ248E1.1, DKFZP564G202, MOX" ENSG00000079931 "Monooxygenase DBH like 1" Q6UVY6 6 132296055-132401475 "Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 64.2;smooth muscle: 78.6" "Cell type enhanced" "Detected in many" "Astrocytes: 92.7;Basal squamous epithelial cells: 153.1;Early spermatids: 70.2;Endometrial stromal cells: 57.8;Excitatory neurons: 36.0;Oligodendrocyte precursor cells: 33.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 33 "memory B-cell: 3.1;naive B-cell: 1.7;plasmacytoid DC: 5.1" "Group enriched" "Detected in many" 41 "B-cells: 3.1;dendritic cells: 5.1" "Cell line enhanced" "Detected in many" "ASC diff: 164.8;ASC TERT1: 131.7;BJ: 106.1;fHDF/TERT166: 196.5;HBF TERT88: 120.6;U-2197: 310.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035740 Approved Approved Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 18: U-2197 - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" Cytosol "HPA035740: AB_10610141" "unprognostic (1.74e-1)" "unprognostic (1.28e-1)" "unprognostic (8.05e-2)" "unprognostic (9.87e-3)" "unprognostic (5.62e-2)" "prognostic favorable (7.09e-5)" "unprognostic (5.77e-2)" "unprognostic (2.48e-1)" "unprognostic (6.55e-2)" "unprognostic (2.21e-1)" "unprognostic (1.60e-1)" "unprognostic (9.54e-2)" "unprognostic (2.56e-3)" "prognostic unfavorable (3.72e-4)" "unprognostic (2.92e-2)" "unprognostic (6.24e-2)" "unprognostic (1.73e-2)" 2.8 36.5 18.0 5.7 10.6 0.1 2.5 3.1 11.7 25.7 3.5 13.4 5.2 64.2 11.0 23.5 3.4 28.7 5.4 10.9 4.0 37.0 1.8 25.3 6.2 3.5 3.8 0.8 2.2 0.5 4.5 1.4 3.9 32.0 8.8 5.0 12.2 39.6 0.3 14.4 7.5 78.6 3.6 4.7 5.2 1.8 6.7 2.1 1.8 0.5 15.6 19.1 12.8 10.8 0.1 0.9 4.1 0.0 164.8 131.7 0.2 106.1 71.0 37.7 65.8 0.2 1.2 0.4 0.1 196.5 30.9 0.1 1.4 0.5 120.6 0.0 19.3 0.0 0.1 0.0 1.5 0.1 0.1 31.8 0.0 76.6 2.5 46.6 0.0 0.0 0.0 7.8 22.4 0.0 0.1 0.2 3.5 0.0 0.7 1.1 0.4 0.2 46.3 0.4 2.8 0.2 0.0 0.4 2.4 9.6 0.1 5.9 0.5 17.4 15.9 310.0 56.1 4.1 0.0 0.0 43.9 0.0 51.9 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.1 18.0 10.6 3.1 11.7 10.9 4.0 3.5 3.8 3.9 3.6 6.7 10.8 0.4 0.0 1.3 92.7 5.4 28.0 0.4 0.1 153.1 0.3 0.4 0.6 0.7 0.0 2.5 1.8 0.0 0.9 2.7 0.0 0.0 0.6 70.2 1.0 57.8 0.6 0.0 0.0 36.0 0.0 1.5 23.9 0.5 1.2 3.8 0.0 0.0 0.0 0.4 0.0 8.6 0.0 0.0 0.3 4.7 11.8 0.3 0.3 7.2 4.7 0.0 16.4 0.0 33.7 1.1 0.4 0.0 0.4 9.5 1.5 0.0 0.3 0.0 0.8 0.0 6.2 3.3 0.5 0.8 14.6 6.8 0.0 0.5 0.1 0.1 0.0 MROH2A HEATR7B1 ENSG00000185038 "Maestro heat like repeat family member 2A" A6NES4 2 233775679-233833423 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 1.7;thyroid gland: 1.6" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 3.4;Early spermatids: 1.3;Hepatocytes: 1.0;Late spermatids: 1.7;Spermatocytes: 1.5" "Cancer enhanced" "Detected in some" "urothelial cancer: 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "RT4: 6.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA052107 Uncertain Uncertain Cytosol NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 15: RT4 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA052107: AB_2681729" "unprognostic (7.00e-2)" "unprognostic (3.37e-3)" "unprognostic (4.77e-1)" "unprognostic (1.65e-2)" "unprognostic (4.03e-1)" "unprognostic (1.71e-1)" "unprognostic (1.87e-1)" "unprognostic (4.41e-2)" "unprognostic (2.69e-1)" "unprognostic (1.67e-1)" "unprognostic (4.32e-2)" "unprognostic (5.05e-2)" "unprognostic (4.06e-9)" "unprognostic (5.65e-2)" "unprognostic (3.90e-2)" "unprognostic (1.18e-1)" "unprognostic (1.41e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.7 0.1 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.4 3.4 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 1.5 0.6 0.6 0.1 0.0 0.0 0.0 0.0 0.3 MSI2 ENSG00000153944 "Musashi RNA binding protein 2" Q96DH6 17 57255851-57684689 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 830.2;Cone photoreceptor cells: 754.8;Rod photoreceptor cells: 500.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "REH: 184.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022300, HPA068990" Approved Supported Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 14: REH - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "CAB022300: , HPA068990: " "unprognostic (4.73e-2)" "unprognostic (2.28e-1)" "unprognostic (3.42e-2)" "unprognostic (1.26e-1)" "unprognostic (1.12e-1)" "unprognostic (1.08e-1)" "unprognostic (4.20e-2)" "unprognostic (2.20e-2)" "unprognostic (4.89e-2)" "unprognostic (2.96e-1)" "unprognostic (4.17e-2)" "unprognostic (1.18e-1)" "prognostic favorable (9.22e-8)" "prognostic favorable (2.00e-4)" "unprognostic (4.87e-2)" "unprognostic (1.57e-1)" "unprognostic (2.72e-3)" 7.5 69.1 52.2 13.2 52.8 20.2 18.9 53.0 43.4 12.1 105.7 14.1 10.3 14.0 49.9 9.3 22.9 18.3 33.4 42.0 74.6 36.8 7.5 8.3 22.2 82.5 88.6 46.4 12.8 88.6 44.7 22.6 63.4 21.5 15.6 126.0 17.0 21.0 60.7 8.0 11.7 7.6 63.5 17.2 16.6 15.4 58.8 46.5 25.6 43.4 19.6 19.8 8.2 56.0 11.8 18.8 79.0 28.6 7.7 7.8 53.9 13.7 16.4 16.8 10.1 23.6 20.4 56.9 47.1 9.4 13.1 11.8 50.6 18.1 34.8 77.1 31.7 26.2 46.5 58.7 17.8 28.0 23.9 10.4 24.3 2.4 29.9 24.1 19.3 46.6 52.5 42.3 67.6 27.1 136.8 7.2 26.0 64.0 33.2 184.3 109.8 45.5 46.2 84.0 76.6 154.5 22.1 22.9 63.7 33.8 36.9 21.0 22.4 11.2 27.2 9.2 23.0 57.3 51.7 68.8 29.9 16.7 70.2 2.7 0.1 1.9 0.7 0.1 0.6 0.7 0.8 0.7 0.2 0.4 0.6 0.7 0.1 0.8 0.8 1.1 1.6 0.2 52.2 52.8 53.0 43.4 42.0 74.6 82.5 88.6 63.4 63.5 58.8 56.0 20.5 6.4 28.7 830.2 50.5 24.0 74.9 54.5 34.7 202.1 53.2 33.9 99.1 54.3 42.3 75.4 754.8 117.9 37.5 29.5 123.3 49.3 15.3 150.2 30.8 28.1 98.2 35.5 67.6 14.2 25.9 34.2 34.1 70.8 41.8 178.7 29.6 31.5 20.4 294.4 175.5 51.8 109.9 12.6 16.4 27.2 64.7 20.1 39.2 158.3 13.2 220.6 22.6 249.3 111.6 12.8 24.3 77.5 88.8 74.7 11.6 51.2 106.0 500.1 13.1 42.3 30.6 3.1 7.6 28.2 16.1 149.3 50.6 113.5 37.8 92.4 MST1R "CD136, CDw136, PTK8, RON, SEA" ENSG00000164078 "Macrophage stimulating 1 receptor" Q04912 3 49887002-49903873 "CD markers, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 62.3;stomach 1: 42.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 25.6;Distal enterocytes: 53.9;Gastric mucus-secreting cells: 108.6;Intestinal goblet cells: 25.7;Pancreatic endocrine cells: 31.2;Paneth cells: 30.3;Proximal enterocytes: 27.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 39.3;CAPAN-2: 98.8;HaCaT: 56.3;HBEC3-KT: 59.4;hTCEpi: 83.4;RT4: 67.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA007657, HPA008180, CAB008972" Enhanced Approved Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB008972: , HPA007657: AB_1079292, HPA008180: AB_1079291" "unprognostic (3.84e-3)" "unprognostic (3.86e-1)" "unprognostic (1.92e-1)" "unprognostic (7.33e-3)" "unprognostic (3.82e-2)" "unprognostic (2.32e-1)" "unprognostic (8.07e-3)" "unprognostic (1.54e-2)" "unprognostic (4.12e-2)" "unprognostic (2.15e-1)" "unprognostic (1.24e-3)" "unprognostic (2.28e-1)" "unprognostic (8.08e-3)" "unprognostic (2.38e-1)" "unprognostic (2.18e-1)" "unprognostic (8.00e-3)" "prognostic favorable (2.33e-5)" 5.1 0.3 1.1 5.1 1.1 0.2 3.8 1.1 1.7 5.7 1.3 26.5 25.2 1.3 1.2 17.5 1.7 11.4 3.2 1.1 0.9 3.4 1.1 9.5 2.5 0.9 0.8 1.0 5.8 0.1 2.7 0.8 0.9 4.7 20.1 0.2 5.4 1.0 1.3 62.3 23.9 2.0 0.8 1.6 42.6 8.4 0.9 8.8 3.4 0.7 5.6 9.2 11.5 1.0 39.3 14.4 0.1 0.6 0.0 0.0 2.2 0.5 0.1 0.0 0.0 4.1 98.8 1.7 8.8 0.5 0.1 56.3 0.0 59.4 0.0 0.9 1.0 0.1 25.9 0.9 0.9 0.0 1.2 0.3 83.4 0.2 11.7 0.2 0.1 0.2 0.8 0.3 0.0 5.1 0.1 0.1 0.3 33.1 34.6 2.9 0.0 1.1 35.8 67.9 1.0 0.1 11.5 22.6 0.2 0.1 17.7 0.9 0.3 0.0 0.3 0.3 0.1 0.5 0.2 0.2 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 1.1 1.1 1.7 1.1 0.9 0.9 0.8 0.9 0.8 0.9 1.0 1.6 25.6 10.3 0.7 1.0 8.8 2.2 14.2 6.8 0.0 2.8 2.5 1.0 0.0 10.6 0.0 0.0 0.1 0.2 53.9 0.0 6.4 15.4 2.9 0.8 0.6 4.2 0.0 1.1 10.0 0.4 0.8 108.6 5.3 0.0 0.1 0.0 0.0 0.1 0.0 1.1 25.7 2.0 0.0 1.4 10.5 0.3 0.5 0.0 1.0 0.6 0.0 1.0 2.0 0.1 31.2 30.3 0.0 0.5 2.2 27.6 0.1 7.6 0.0 0.0 0.5 0.9 1.3 1.5 3.2 4.7 0.0 0.5 0.0 20.1 6.2 MSTO1 "FLJ10504, LST005, misato, MST" ENSG00000125459 "Misato mitochondrial distribution and morphology regulator 1" Q9BUK6 1 155610205-155614951 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1482.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005899, HPA005914, HPA006075" Approved Enhanced Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 18: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA005899: AB_2667460, HPA005914: AB_2667466, HPA006075: " "unprognostic (1.80e-2)" "unprognostic (3.43e-1)" "unprognostic (6.49e-2)" "unprognostic (2.65e-1)" "unprognostic (1.15e-1)" "unprognostic (4.46e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (9.63e-2)" "unprognostic (1.26e-1)" "unprognostic (5.28e-2)" "unprognostic (3.73e-2)" "unprognostic (3.67e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.56e-1)" "unprognostic (1.12e-1)" "unprognostic (5.35e-2)" "unprognostic (1.28e-1)" 18.5 18.2 7.9 10.2 8.2 7.3 18.9 9.0 9.4 18.0 7.6 11.7 8.7 16.1 18.0 14.7 16.7 7.2 14.1 9.0 8.8 17.8 31.7 12.7 11.5 10.0 9.4 17.0 25.1 14.9 24.3 8.6 10.3 20.7 9.0 7.8 14.4 14.8 6.8 11.9 15.7 11.8 7.9 21.2 14.6 23.1 10.0 8.6 18.5 4.7 10.7 15.9 12.8 8.4 23.0 31.1 26.7 41.1 21.9 18.5 33.3 28.8 24.5 35.1 27.9 30.8 14.3 39.5 26.1 25.9 22.6 24.7 40.2 38.8 24.2 15.3 33.6 34.1 29.5 17.8 34.8 36.7 26.4 19.2 19.4 38.8 55.7 15.6 29.2 28.5 28.4 17.3 29.3 37.7 24.7 24.9 35.4 38.6 40.8 21.2 25.0 35.4 29.6 23.1 22.0 26.7 20.2 60.6 26.3 31.2 33.5 49.2 19.5 22.2 24.3 24.0 44.9 36.4 33.8 29.3 25.0 35.6 30.9 3.5 5.9 0.4 10.0 8.3 11.2 7.4 9.4 9.1 8.4 5.5 9.8 6.2 0.7 9.6 5.5 8.4 7.5 6.8 7.9 8.2 9.0 9.4 9.0 8.8 10.0 9.4 10.3 7.9 10.0 8.4 4.6 6.4 6.0 3.9 8.8 2.7 6.1 8.6 5.2 9.1 6.6 4.4 9.7 2.8 7.2 7.3 22.9 7.9 5.8 2.9 3.9 9.6 324.5 4.2 8.2 6.1 5.4 3.8 2.0 13.4 23.7 6.3 12.8 4.7 14.5 9.5 2.2 7.1 8.7 11.8 2.1 4.9 2.0 2.6 3.5 1482.8 9.0 5.5 3.6 1.0 6.3 4.6 3.1 2.5 2.2 8.0 0.9 11.3 17.0 5.5 2.8 9.9 10.9 9.7 0.0 6.7 6.4 23.0 12.6 6.3 1.4 6.6 7.2 7.1 4.6 2.8 MT-ND3 "MTND3, NAD3, ND3" ENSG00000198840 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3" P03897 MT 10059-10404 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 184151.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 37883.1;Proximal enterocytes: 23257.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 23280.2;HeLa: 21694.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063296 Enhanced Uncertain Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "HPA063296: AB_2684978" "unprognostic (1.71e-2)" "unprognostic (1.05e-1)" "unprognostic (8.10e-2)" "unprognostic (3.07e-1)" "unprognostic (2.48e-1)" "unprognostic (1.36e-1)" "prognostic favorable (4.63e-5)" "unprognostic (2.45e-2)" "unprognostic (7.13e-2)" "unprognostic (8.85e-2)" "unprognostic (1.76e-3)" "unprognostic (1.74e-1)" "unprognostic (7.63e-2)" "unprognostic (2.51e-2)" "unprognostic (1.19e-1)" "unprognostic (2.07e-1)" "unprognostic (5.65e-3)" 31356.6 42036.1 79316.1 3483.1 80070.8 4077.5 25368.6 75454.6 124729.8 8985.8 81148.8 26406.1 11478.9 8410.1 8217.8 12712.6 10495.3 3610.0 184151.1 75602.8 85299.8 84244.0 72988.4 9018.3 3610.8 89729.0 83678.9 9439.2 26008.9 14199.5 13387.4 6281.1 85648.8 23996.0 10095.2 6318.4 14787.5 8355.4 70313.2 16879.7 21792.1 4960.7 71704.7 11407.9 36122.2 10815.9 84470.1 3654.8 14626.9 73367.5 3934.1 18841.5 10373.7 74059.9 3324.0 5255.7 3450.6 3399.1 23280.2 4613.0 2871.7 2717.2 1592.1 1441.9 1616.6 7973.2 5004.1 3408.8 4095.7 3519.2 2600.2 6710.1 1504.4 5941.5 2461.9 4945.3 7153.7 3371.4 21694.2 13369.3 3629.0 5018.8 4874.1 8076.0 10704.2 2416.7 2704.4 8547.3 2285.4 3853.4 2711.1 3864.5 2747.1 10748.2 2646.2 6609.3 1779.4 9407.1 4824.1 2262.5 3389.7 3164.0 8729.4 8962.3 1417.0 3058.9 1310.8 2587.7 5763.8 8928.3 6011.6 7960.5 3898.6 2207.0 3378.3 3876.8 2982.9 1492.1 2128.5 7735.7 1794.0 2976.6 1284.1 2263.7 612.4 386.5 336.6 346.8 441.9 672.5 393.0 417.4 321.5 686.4 568.4 769.3 968.2 447.0 335.5 312.1 262.5 353.1 79316.1 80070.8 75454.6 124729.8 75602.8 85299.8 89729.0 83678.9 85648.8 71704.7 84470.1 74059.9 4254.0 701.9 879.1 0.0 6320.6 1987.5 2507.9 1722.8 5384.4 0.0 3350.4 5821.1 37883.1 9781.1 1560.8 5041.1 0.0 0.0 5039.9 14324.8 1164.1 1320.8 1023.5 11751.2 6030.4 3302.6 2852.4 14390.0 0.0 2870.2 0.0 3063.4 6039.9 17552.8 1453.7 17373.9 10407.8 20920.6 0.0 0.0 0.0 11328.3 870.8 16584.4 1757.6 5643.0 9133.7 4877.6 1858.7 0.0 4964.0 0.0 2775.5 0.0 0.0 2194.1 9034.9 4865.3 6343.6 1554.6 23257.1 8457.2 2113.9 0.0 7001.2 6561.9 3856.1 5442.6 3706.2 3801.0 1888.8 0.0 4844.1 3423.5 10381.8 2314.6 MTHFD1 "MTHFC, MTHFD" ENSG00000100714 "Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1" 14 64388031-64463457 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 356.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 142.9;Proximal tubular cells: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000704, HPA001290, HPA015006, HPA050052" Approved Enhanced Cytosol NA Yes "Cluster 43: B-cells - Humoral immune response" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA000704: AB_1079424, HPA001290: AB_1854177, HPA015006: AB_1854178, HPA050052: AB_2680998" "unprognostic (3.58e-2)" "unprognostic (5.50e-3)" "unprognostic (1.24e-1)" "unprognostic (2.46e-2)" "unprognostic (1.37e-1)" "unprognostic (7.01e-2)" "unprognostic (8.85e-3)" "unprognostic (7.62e-3)" "unprognostic (1.28e-1)" "unprognostic (2.29e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (1.84e-1)" "prognostic favorable (5.93e-5)" "unprognostic (2.45e-2)" "unprognostic (1.75e-1)" "unprognostic (7.30e-2)" "unprognostic (2.29e-2)" 56.4 18.0 8.6 20.0 17.4 27.0 29.8 8.3 12.3 16.9 15.0 23.3 19.7 16.1 9.9 25.1 16.0 13.1 28.1 12.9 8.1 55.3 356.9 15.4 23.6 7.5 7.8 24.9 23.8 27.5 9.2 13.3 7.0 12.9 27.5 3.6 15.6 13.8 64.1 17.1 18.9 20.0 7.2 14.5 17.9 4.7 8.9 30.2 20.5 61.9 27.7 18.6 16.6 8.3 294.1 164.9 58.5 143.6 70.5 53.4 95.7 106.4 83.3 148.1 147.4 161.2 144.2 103.3 49.6 67.1 68.3 146.0 177.6 111.2 160.4 107.3 117.9 122.2 143.5 131.8 50.6 104.5 81.2 43.0 37.3 124.3 66.4 57.5 93.1 98.1 108.5 98.7 114.7 270.1 179.9 62.3 118.0 186.5 160.4 138.3 201.2 114.4 110.5 160.9 128.7 49.0 183.7 111.4 58.3 54.0 164.4 58.6 51.5 115.1 184.1 102.2 134.2 58.8 65.6 177.9 107.4 125.2 134.8 0.4 11.7 0.1 9.7 19.5 13.0 27.0 10.1 12.3 17.7 15.3 7.8 10.7 0.9 17.8 16.7 4.0 19.5 12.2 8.6 17.4 8.3 12.3 12.9 8.1 7.5 7.8 7.0 7.2 8.9 8.3 8.1 19.2 23.5 15.0 16.2 13.8 14.2 14.7 13.6 0.0 9.8 8.1 43.9 15.7 19.5 16.5 0.0 30.6 10.8 7.9 41.1 16.9 1.4 6.8 11.7 12.3 3.0 42.3 19.5 10.3 30.9 14.9 15.3 8.7 50.7 27.2 12.8 142.9 25.3 0.0 15.6 14.3 2.0 13.0 11.0 1.5 13.1 12.3 14.2 8.4 13.3 0.0 8.2 14.1 10.9 11.7 6.3 13.2 24.1 10.2 8.2 75.3 11.5 0.0 19.7 13.1 19.3 0.9 8.9 19.5 10.7 9.9 16.6 21.4 24.6 12.7 MTHFS HsT19268 ENSG00000136371 "Methenyltetrahydrofolate synthetase" P49914 15 79833585-79897379 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 253.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 205.5;monocytes: 150.8;Proximal tubular cells: 201.6;Syncytiotrophoblasts: 253.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 134.1" "Group enriched" "Detected in all" 5 "granulocytes: 134.1;monocytes: 49.1" "Low cell line specificity" "Detected in many" "HPA008067, HPA054177" Approved Supported Cytosol NA NA 13000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA008067: AB_1078882, HPA054177: AB_2682405" "unprognostic (4.57e-2)" "unprognostic (9.76e-2)" "unprognostic (6.11e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (8.52e-4)" "unprognostic (9.13e-3)" "prognostic favorable (1.29e-6)" "unprognostic (1.34e-2)" "unprognostic (1.03e-1)" "unprognostic (6.18e-3)" "unprognostic (2.91e-2)" "unprognostic (2.76e-1)" "prognostic favorable (2.04e-4)" "unprognostic (1.36e-1)" "unprognostic (2.85e-1)" "unprognostic (7.60e-2)" "unprognostic (2.90e-1)" 21.9 19.8 8.0 4.6 8.2 5.0 19.0 9.6 12.7 9.9 6.9 12.0 13.7 9.0 10.3 10.1 9.4 7.0 19.0 8.0 9.2 53.1 253.4 17.8 6.4 8.7 9.3 8.6 32.8 26.3 21.5 8.3 9.1 19.5 6.4 5.9 13.6 5.5 20.2 6.2 14.5 6.2 8.8 14.9 19.5 12.1 8.7 10.6 15.9 11.1 10.8 12.4 9.9 9.1 12.6 35.8 5.0 2.6 15.8 12.0 11.9 8.8 13.0 16.4 10.5 34.5 22.4 15.1 25.1 15.5 15.0 19.5 31.9 10.7 15.4 14.7 28.4 14.8 22.9 39.8 25.3 7.8 0.8 17.5 27.8 8.1 23.0 19.6 7.4 16.0 28.8 12.0 17.4 36.0 10.2 36.1 15.6 51.4 17.0 10.8 17.2 25.8 35.1 34.3 8.9 4.8 25.1 14.2 43.8 20.0 17.3 13.0 3.3 5.7 11.1 3.6 7.1 6.8 20.2 17.8 3.3 25.9 6.2 17.5 25.7 73.5 9.4 35.3 12.4 13.5 13.7 12.9 12.3 11.1 16.5 12.6 134.1 17.8 49.1 13.3 15.7 19.1 8.0 8.2 9.6 12.7 8.0 9.2 8.7 9.3 9.1 8.8 8.7 9.1 11.3 19.2 44.0 0.0 20.7 10.7 9.9 63.0 35.9 0.0 25.5 32.5 0.7 58.6 34.3 22.0 0.0 68.1 10.1 10.0 64.6 55.8 2.2 11.9 7.8 10.5 17.6 36.6 0.0 75.7 37.1 13.5 39.8 11.0 8.8 7.2 21.8 205.5 45.7 0.0 0.0 18.7 24.4 22.1 34.8 3.8 13.7 29.3 21.4 0.0 150.8 0.0 35.0 0.0 0.0 75.3 35.9 15.8 13.3 13.3 101.7 201.6 29.9 0.0 13.1 8.4 10.5 6.7 8.5 21.1 8.1 253.8 22.2 9.2 24.9 7.7 MTR cblG ENSG00000116984 "5-methyltetrahydrofolate-homocysteine methyltransferase" Q99707 1 236795260-236921278 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" "Methyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 100.0;Glandular and luminal cells: 130.9;Inhibitory neurons: 106.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044474, HPA054915" Approved Supported Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 44: Endometrium - Transcription" Cytosol "HPA044474: AB_10966696, HPA054915: AB_2732589" "unprognostic (2.12e-1)" "unprognostic (1.03e-1)" "unprognostic (6.96e-2)" "unprognostic (1.99e-1)" "unprognostic (1.35e-1)" "unprognostic (1.76e-1)" "unprognostic (4.87e-1)" "unprognostic (1.02e-1)" "unprognostic (2.48e-2)" "unprognostic (3.34e-1)" "unprognostic (5.73e-2)" "unprognostic (1.63e-1)" "unprognostic (1.67e-2)" "unprognostic (8.84e-3)" "unprognostic (1.88e-1)" "prognostic unfavorable (5.75e-4)" "unprognostic (8.10e-2)" 9.1 6.6 4.3 6.9 5.4 4.6 8.0 5.2 5.4 10.1 6.5 11.1 4.8 10.2 10.5 5.0 11.9 8.9 15.0 4.9 4.6 12.7 6.0 7.1 8.1 6.7 5.3 14.6 13.0 20.2 6.4 11.6 6.9 7.6 5.0 5.6 6.4 9.1 16.6 9.3 7.1 8.7 4.8 9.4 9.0 9.0 4.8 10.0 13.4 18.1 7.0 10.3 7.6 6.5 17.6 11.0 13.0 8.8 22.6 20.3 15.3 14.9 14.8 18.8 19.0 12.6 12.5 40.0 13.2 16.6 8.7 10.6 18.4 13.1 20.4 19.8 13.7 23.7 14.2 18.3 15.1 37.2 13.3 28.9 7.0 22.9 17.9 11.5 22.3 19.8 33.1 16.4 13.1 10.1 19.6 10.3 16.2 12.9 5.4 20.9 24.8 24.2 11.2 21.3 11.1 27.8 17.7 11.9 14.8 9.3 16.7 13.0 28.8 24.1 9.1 19.6 18.8 34.4 12.3 22.7 17.2 21.1 26.2 0.6 0.5 1.5 1.1 0.8 2.3 0.7 1.4 1.4 0.7 0.8 1.4 1.5 0.0 0.9 0.5 0.5 0.9 0.9 4.3 5.4 5.2 5.4 4.9 4.6 6.7 5.3 6.9 4.8 4.8 6.5 23.0 57.7 35.0 53.8 25.8 8.2 8.3 8.3 17.1 0.0 10.7 11.9 100.0 20.0 10.9 40.5 0.0 24.2 25.9 3.4 1.9 13.8 9.8 57.5 80.1 21.4 8.4 23.5 87.7 14.8 9.2 22.8 15.8 130.9 30.4 35.0 15.4 10.8 14.4 0.0 106.8 7.7 4.1 16.6 6.8 6.2 23.9 17.1 10.6 47.8 15.3 0.0 19.6 62.8 73.6 12.3 8.0 33.1 20.3 14.9 9.7 9.1 13.3 0.0 6.6 39.4 23.2 17.2 22.0 11.5 5.1 22.6 26.1 40.2 12.0 6.4 MTURN "C7orf41, Ells1, FLJ25903" ENSG00000180354 "Maturin, neural progenitor differentiation regulator homolog" Q8N3F0 7 30134986-30162762 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 14 "brain: 1933.2;choroid plexus: 740.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 156.5" "Cancer enhanced" "Detected in all" "glioma: 29.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 8.2" "Group enriched" "Detected in many" 5 "granulocytes: 8.2;NK-cells: 2.1" "Cell line enhanced" "Detected in many" "ASC diff: 52.9;HEL: 96.2;SCLC-21H: 68.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029507 Enhanced Approved Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA029507: AB_10601149" "unprognostic (1.99e-1)" "unprognostic (1.38e-2)" "unprognostic (3.70e-1)" "unprognostic (7.14e-2)" "unprognostic (1.84e-1)" "unprognostic (1.72e-1)" "unprognostic (1.56e-1)" "unprognostic (1.89e-3)" "unprognostic (9.80e-2)" "unprognostic (1.94e-1)" "unprognostic (1.11e-3)" "unprognostic (8.11e-3)" "prognostic favorable (7.64e-13)" "unprognostic (9.50e-2)" "unprognostic (7.64e-2)" "unprognostic (4.64e-1)" "unprognostic (3.26e-1)" 88.4 10.8 1190.3 9.7 1373.7 23.3 41.6 1103.3 1933.2 25.7 740.3 35.8 5.4 19.4 95.3 19.5 21.1 10.4 25.0 946.3 1044.1 50.3 4.1 20.9 5.4 1359.2 1275.8 33.4 12.9 15.7 17.4 7.5 1312.7 19.2 10.0 41.0 35.2 23.8 36.6 23.2 13.8 17.0 1311.0 8.3 26.4 10.9 1260.6 7.5 14.7 59.8 5.4 32.1 20.0 1483.6 12.5 2.1 7.1 7.6 52.9 35.9 6.4 6.0 7.0 2.0 2.8 1.0 5.0 0.7 4.8 13.3 11.0 2.4 16.4 23.6 6.4 5.4 13.2 96.2 16.1 6.7 4.1 4.8 30.8 17.9 10.8 6.2 10.9 8.6 3.2 13.1 6.4 5.0 13.8 4.8 5.6 2.3 4.9 11.6 7.5 0.5 16.3 21.4 24.1 5.1 68.7 18.2 3.8 19.1 19.4 6.6 13.5 7.1 15.5 7.8 8.5 16.6 8.5 8.3 12.7 1.1 10.4 10.3 4.0 8.2 0.3 3.6 0.3 0.2 0.1 0.5 0.2 0.1 0.4 0.3 0.1 0.3 2.2 2.1 0.0 1.0 0.7 1.4 1190.3 1373.7 1103.3 1933.2 946.3 1044.1 1359.2 1275.8 1312.7 1311.0 1260.6 1483.6 38.9 16.0 20.0 18.6 5.6 37.5 17.8 6.6 13.1 0.0 48.3 40.8 27.6 17.2 10.2 44.1 0.0 2.6 32.1 3.2 156.5 8.3 14.1 46.6 16.9 18.9 54.1 35.1 55.9 8.6 7.3 24.6 7.7 52.6 6.3 16.6 26.0 5.0 5.3 0.0 34.7 9.1 0.0 23.4 16.8 32.5 17.1 29.3 55.2 37.5 12.1 0.0 6.2 16.6 77.1 10.4 5.9 12.4 4.9 26.6 0.4 11.2 26.6 0.0 6.6 17.8 30.2 2.0 7.3 11.4 36.8 2.2 7.4 5.9 6.0 23.0 MVP "LRP, VAULT1" ENSG00000013364 "Major vault protein" Q14764 16 29820394-29848039 "Cancer-related genes, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" Ribonucleoprotein "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 504.7;Exocrine glandular cells: 310.8;Paneth cells: 338.3;Proximal enterocytes: 514.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "TIME: 429.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002321, CAB002752, CAB022717, HPA064740" Enhanced Supported Cytosol NA NA 110000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 14: B-cells - Humoral immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB002752: , CAB022717: , HPA002321: AB_1079277, HPA064740: AB_2685342" "prognostic favorable (4.51e-4)" "unprognostic (1.06e-1)" "unprognostic (2.77e-1)" "unprognostic (1.80e-1)" "unprognostic (8.17e-2)" "unprognostic (3.03e-2)" "unprognostic (1.11e-2)" "unprognostic (2.22e-2)" "unprognostic (6.03e-3)" "unprognostic (2.19e-1)" "unprognostic (6.85e-3)" "unprognostic (2.86e-1)" "prognostic favorable (5.49e-5)" "unprognostic (2.22e-1)" "unprognostic (5.19e-2)" "unprognostic (5.69e-3)" "unprognostic (2.65e-2)" 84.4 181.7 26.2 96.0 35.7 46.4 71.0 29.9 33.7 76.6 32.5 165.6 154.7 73.1 14.3 75.4 73.3 74.3 64.4 26.0 31.9 113.4 66.9 121.9 71.1 43.1 36.4 103.3 101.9 18.9 47.5 38.0 35.5 59.7 96.5 6.3 77.1 38.9 50.6 61.1 158.9 69.0 32.6 114.0 107.8 39.4 42.3 31.3 60.6 32.4 47.6 80.0 72.9 38.3 64.8 191.8 0.8 1.7 212.0 275.0 25.9 163.4 258.5 88.0 121.4 24.7 216.8 3.1 134.9 231.0 108.9 78.1 0.8 129.5 42.2 166.4 1.8 3.0 81.6 87.6 190.1 2.3 60.2 366.9 96.1 207.0 58.3 170.5 274.5 6.2 0.5 92.1 167.7 18.3 0.8 4.3 2.4 93.4 11.6 2.1 0.7 32.5 229.1 114.6 10.5 7.6 41.8 53.8 31.8 6.5 9.5 18.7 429.3 124.2 59.4 119.9 62.0 66.6 45.1 2.7 294.6 4.8 24.9 50.4 140.8 56.3 70.9 214.3 55.1 36.6 80.7 73.6 113.1 27.2 59.4 54.0 160.0 73.7 204.0 69.2 90.7 164.4 26.2 35.7 29.9 33.7 26.0 31.9 43.1 36.4 35.5 32.6 42.3 38.3 34.2 48.1 115.5 9.8 31.2 19.6 39.3 120.3 16.5 4.8 17.9 10.0 12.9 82.9 112.0 69.9 2.1 113.6 31.2 504.7 45.0 272.7 4.9 43.9 25.9 40.9 56.5 8.6 3.2 310.8 71.4 52.8 120.8 65.9 33.7 14.8 36.4 23.8 78.0 8.4 3.4 177.1 95.6 41.0 27.1 21.1 57.5 55.0 32.0 9.4 223.3 3.0 59.8 0.0 23.1 278.5 338.3 47.8 36.4 25.0 514.8 194.8 110.3 4.9 19.7 23.8 51.3 2.7 1.8 20.7 21.9 264.5 45.1 24.7 206.8 56.7 MXD4 "bHLHc12, MAD4, MST149, MSTP149" ENSG00000123933 "MAX dimerization protein 4" Q14582 4 2247432-2262109 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 169.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 68.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053363 Supported Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA053363: AB_2682128" "unprognostic (1.26e-1)" "unprognostic (1.09e-1)" "unprognostic (2.37e-2)" "unprognostic (2.84e-2)" "unprognostic (3.54e-2)" "prognostic favorable (2.21e-5)" "unprognostic (1.64e-1)" "unprognostic (5.94e-2)" "unprognostic (8.37e-2)" "unprognostic (1.57e-1)" "prognostic favorable (1.39e-5)" "unprognostic (5.65e-2)" "unprognostic (1.09e-3)" "unprognostic (2.13e-1)" "unprognostic (1.46e-1)" "unprognostic (2.64e-2)" "unprognostic (4.12e-2)" 38.6 42.0 43.9 11.3 39.8 29.8 35.9 62.1 58.4 31.1 38.2 35.2 18.3 37.1 11.6 21.0 27.9 15.1 36.2 40.9 37.7 38.8 20.6 38.5 20.2 40.6 40.5 23.2 25.3 12.4 63.5 14.3 39.7 33.0 7.2 5.9 35.0 25.0 24.1 25.9 28.6 14.0 37.5 57.6 31.2 22.1 41.2 23.2 33.4 14.4 9.1 25.1 19.4 39.6 2.3 8.3 12.9 15.5 44.2 32.6 3.0 16.4 16.6 12.0 12.2 2.0 7.1 7.1 36.1 25.0 6.4 11.2 3.7 13.0 3.1 6.3 39.5 1.3 29.0 23.6 32.4 5.5 14.5 51.1 22.9 3.9 6.1 26.5 28.9 10.3 9.8 11.6 11.3 16.2 12.6 31.6 5.1 9.6 36.4 8.5 4.4 15.1 14.2 13.0 20.8 38.7 15.4 7.5 12.3 15.7 35.2 34.4 68.7 13.3 5.3 9.9 3.7 17.6 13.2 2.8 18.2 4.9 4.0 7.2 2.7 3.4 3.3 3.0 2.7 2.2 3.0 3.3 2.5 2.0 1.5 1.5 1.1 2.0 3.0 7.2 4.0 1.4 43.9 39.8 62.1 58.4 40.9 37.7 40.6 40.5 39.7 37.5 41.2 39.6 169.7 19.2 19.9 48.0 37.9 19.1 15.3 13.6 7.4 81.6 67.8 67.1 18.4 17.2 16.1 60.7 87.6 44.3 129.6 47.9 15.6 16.5 10.1 39.6 81.9 54.7 33.6 20.6 11.6 18.3 48.4 53.6 23.0 42.8 24.1 37.9 103.5 35.5 50.3 65.6 20.5 55.9 10.2 72.9 27.5 28.8 33.2 58.8 23.2 27.2 21.6 67.9 68.0 19.1 19.7 17.5 31.8 56.4 54.0 28.7 44.0 22.1 13.4 97.1 26.3 39.6 48.5 7.0 37.0 17.3 26.3 32.7 54.7 100.5 38.2 13.1 MYO15B MYO15BP ENSG00000266714 "Myosin XVB" Q96JP2 17 75588058-75626849 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 179.2" "Group enriched" "Detected in many" 4 "Distal enterocytes: 275.4;Paneth cells: 294.2;Proximal enterocytes: 127.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A549: 46.4;HEL: 17.7;HMC-1: 24.9;THP-1: 37.7" "Not detected" "Not detected" "HPA022857, HPA023105" Approved Cytosol No No "Cluster 34: Basophils - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA022857: AB_1848813, HPA023105: AB_1859526" "prognostic favorable (9.34e-4)" "unprognostic (7.55e-2)" "unprognostic (6.99e-2)" "unprognostic (1.51e-1)" "unprognostic (2.12e-1)" "unprognostic (5.59e-4)" "unprognostic (7.29e-3)" "unprognostic (1.48e-1)" "unprognostic (4.97e-2)" "unprognostic (2.28e-1)" "unprognostic (8.54e-3)" "unprognostic (1.04e-2)" "unprognostic (1.49e-1)" "unprognostic (6.39e-2)" "unprognostic (1.68e-1)" "unprognostic (3.35e-1)" "prognostic favorable (6.90e-5)" 40.0 17.3 34.7 17.3 39.2 57.0 38.1 33.7 45.1 74.7 29.6 53.6 179.2 46.1 7.5 18.6 65.6 25.8 44.4 32.0 34.0 76.0 29.8 55.1 19.2 39.9 36.8 87.1 20.5 4.7 28.9 15.0 40.1 56.5 21.5 9.9 23.6 14.0 13.2 15.9 149.0 9.8 35.5 108.2 25.7 20.9 36.7 17.7 65.8 8.0 7.2 29.0 44.0 46.1 0.6 46.4 0.3 1.2 0.3 0.1 0.7 0.0 0.0 0.0 0.0 5.8 13.6 0.1 1.5 0.0 0.6 0.5 0.0 0.0 0.0 0.6 2.8 17.7 9.5 11.6 1.3 0.0 24.9 0.8 0.8 0.0 0.1 0.8 0.3 7.3 1.2 5.1 0.0 5.0 0.4 7.8 0.7 12.3 11.2 12.7 0.3 2.1 0.3 1.0 1.3 3.2 0.3 0.5 1.5 1.4 3.5 37.7 0.1 0.3 1.2 0.2 0.0 1.7 0.2 0.2 0.7 8.9 0.6 1.3 0.3 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.1 0.3 0.0 0.4 0.2 0.0 0.1 34.7 39.2 33.7 45.1 32.0 34.0 39.9 36.8 40.1 35.5 36.7 46.1 13.7 0.0 3.3 44.7 8.4 2.4 2.4 2.0 8.0 4.5 4.0 2.7 7.5 11.5 2.4 9.2 16.7 0.1 11.9 275.4 1.9 1.6 0.7 11.6 8.9 14.6 31.7 9.2 1.1 1.5 0.1 7.1 52.0 8.1 14.0 13.6 21.0 2.1 5.5 1.7 1.4 40.3 12.2 10.0 12.6 2.7 5.6 17.5 3.6 42.2 6.9 4.9 12.3 32.6 46.6 8.8 294.2 4.9 1.4 1.9 127.5 14.4 8.0 13.5 6.6 7.1 8.4 3.3 6.8 2.2 3.0 0.1 6.2 4.7 20.1 1.8 MYO1D "KIAA0727, myr4, PPP1R108" ENSG00000176658 "Myosin ID" O94832 17 32492522-32877177 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 111.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 193.1;Excitatory neurons: 201.4;Oligodendrocytes: 578.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 105.7;CACO-2: 148.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054744 Uncertain Approved Cytosol NA NA "Cluster 37: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA054744: AB_2682589" "unprognostic (3.83e-3)" "unprognostic (1.53e-1)" "unprognostic (9.70e-3)" "unprognostic (3.95e-2)" "unprognostic (6.68e-2)" "unprognostic (1.89e-1)" "unprognostic (1.84e-1)" "unprognostic (2.04e-1)" "unprognostic (8.88e-2)" "unprognostic (5.51e-2)" "unprognostic (1.37e-1)" "unprognostic (1.73e-1)" "prognostic favorable (5.01e-6)" "unprognostic (1.73e-1)" "unprognostic (1.05e-1)" "unprognostic (2.43e-2)" "prognostic unfavorable (4.53e-6)" 37.7 27.5 10.4 15.6 27.3 3.7 21.0 24.1 15.5 25.5 12.7 111.2 84.4 21.0 22.3 36.0 16.6 31.3 13.2 10.7 13.0 27.1 14.3 31.9 6.3 26.5 22.3 24.6 26.2 27.2 12.3 13.9 25.0 17.8 91.6 1.7 33.1 13.0 5.5 40.6 83.7 18.2 18.5 9.5 26.7 9.8 22.4 7.0 41.0 3.6 14.3 24.6 25.8 52.9 32.3 1.5 0.9 0.3 105.7 60.0 1.2 18.9 36.5 3.4 20.9 148.0 50.0 18.2 3.9 83.7 0.8 29.6 3.8 47.0 5.3 2.3 38.6 16.5 0.1 10.5 6.8 0.0 8.6 17.3 29.3 26.7 24.0 0.4 45.8 9.5 28.2 28.9 16.3 38.6 0.1 0.5 5.8 36.2 28.0 0.0 21.1 21.0 14.6 61.8 36.3 6.2 6.4 11.4 93.2 9.1 50.1 0.2 57.2 16.3 8.2 0.6 0.4 35.2 43.4 0.2 21.6 0.0 4.8 0.0 0.0 0.0 0.2 0.0 0.5 0.3 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 10.4 27.3 24.1 15.5 10.7 13.0 26.5 22.3 25.0 18.5 22.4 52.9 14.3 22.4 13.1 5.5 8.4 8.0 10.1 11.7 26.2 0.9 8.8 8.4 5.0 20.0 12.9 23.9 18.8 19.4 2.7 193.1 5.9 20.8 126.0 7.2 2.8 12.3 26.5 8.2 201.4 23.8 3.1 11.4 30.1 21.3 1.3 24.5 3.9 11.0 8.8 0.0 28.9 93.4 10.2 1.6 8.2 37.6 5.9 4.4 16.0 18.7 0.3 1.2 4.1 9.0 578.3 46.4 94.4 18.4 42.8 18.7 126.5 2.5 25.2 0.9 6.6 5.3 22.8 20.5 7.2 25.4 11.2 12.4 5.7 9.8 81.7 23.3 MYO1F ENSG00000142347 "Myosin IF" O00160 19 8520778-8577577 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 96.0;lung: 24.4;lymphoid tissue: 78.1" "Cell type enhanced" "Detected in many" "dendritic cells: 110.2;Kupffer cells: 235.4;Macrophages: 122.7;monocytes: 195.5;NK-cells: 616.9;T-cells: 100.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 263.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 52.4;HL-60: 52.3;HMC-1: 87.9;NB-4: 210.2;THP-1: 154.3;U-937: 84.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055242, HPA056036" Enhanced Enhanced Cytosol NA NA 46000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA055242: AB_2682754, HPA056036: " "unprognostic (4.86e-2)" "unprognostic (5.86e-3)" "unprognostic (1.39e-2)" "unprognostic (1.04e-3)" "unprognostic (1.76e-2)" "unprognostic (2.12e-3)" "unprognostic (2.28e-1)" "unprognostic (2.13e-1)" "unprognostic (2.10e-2)" "unprognostic (2.33e-1)" "unprognostic (7.47e-3)" "unprognostic (2.86e-1)" "prognostic unfavorable (3.27e-4)" "unprognostic (3.23e-1)" "unprognostic (2.64e-2)" "unprognostic (1.57e-1)" "unprognostic (9.35e-2)" 9.6 4.5 5.1 38.9 5.2 96.0 3.5 5.7 7.2 2.7 6.3 5.0 7.4 2.0 0.7 3.3 6.5 10.5 4.6 4.7 5.9 3.8 7.8 24.4 20.7 9.2 7.6 1.2 2.4 1.2 2.2 7.1 8.7 3.7 3.4 0.2 3.7 1.8 1.5 2.7 12.2 6.4 7.5 78.1 6.5 1.4 8.6 5.4 3.0 4.2 8.5 10.2 2.8 10.1 0.1 0.2 0.0 0.2 0.2 0.3 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.2 6.1 0.4 0.0 0.4 0.0 0.0 0.0 52.4 0.2 38.1 0.0 0.0 0.1 52.3 87.9 0.6 0.1 0.0 0.0 0.1 0.0 0.1 0.5 23.8 0.1 0.3 0.1 210.2 0.0 0.1 0.3 1.0 0.0 5.6 0.1 0.0 0.1 0.3 0.0 0.1 0.3 0.1 0.8 154.3 12.3 0.1 0.2 0.2 0.1 0.1 1.9 0.3 0.3 84.3 0.0 64.5 107.6 105.7 56.6 78.7 44.5 5.9 22.3 39.7 62.8 2.8 1.6 17.0 263.2 32.3 98.8 8.1 34.0 101.3 5.1 5.2 5.7 7.2 4.7 5.9 9.2 7.6 8.7 7.5 8.6 10.1 1.9 3.2 12.3 2.0 26.5 3.3 2.4 0.8 1.2 0.7 3.1 4.3 2.6 5.7 2.9 1.8 2.1 5.0 110.2 2.0 1.9 1.7 6.0 0.6 2.9 4.1 1.2 14.3 2.3 0.9 8.2 2.7 3.6 1.2 31.6 2.2 10.8 6.7 75.8 6.7 1.5 2.1 0.0 235.4 49.3 6.8 2.5 122.7 7.2 64.6 195.5 1.5 616.9 1.5 3.4 1.3 3.2 1.2 30.0 1.8 3.0 2.9 0.2 0.8 0.0 3.4 2.2 6.0 3.4 3.6 5.4 5.1 100.1 3.9 2.7 1.9 MYO9B CELIAC4 ENSG00000099331 "Myosin IXB" Q13459 19 17075781-17214537 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, GTPase activation, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 204.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037190, HPA042043" Approved Supported Cytosol NA NA 8400 "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "CAB037190: AB_477214, HPA042043: AB_10796897" "unprognostic (1.92e-1)" "unprognostic (1.79e-3)" "unprognostic (4.35e-2)" "unprognostic (6.63e-2)" "unprognostic (1.70e-1)" "unprognostic (1.18e-3)" "unprognostic (1.99e-2)" "unprognostic (1.31e-1)" "unprognostic (2.61e-2)" "prognostic unfavorable (2.61e-4)" "unprognostic (7.97e-2)" "unprognostic (1.45e-2)" "prognostic unfavorable (5.66e-6)" "unprognostic (1.97e-1)" "unprognostic (1.50e-1)" "unprognostic (2.36e-2)" "unprognostic (5.53e-2)" 41.0 43.6 38.6 52.6 53.3 98.9 32.3 46.7 56.7 44.9 32.6 45.3 17.5 44.5 12.4 32.9 30.3 20.6 37.2 39.2 46.8 26.9 39.1 78.2 60.3 60.3 53.5 22.5 26.4 6.9 25.6 21.3 56.4 46.1 14.8 40.2 28.3 13.5 12.7 29.6 62.0 17.4 45.8 158.1 36.2 64.2 61.3 33.1 26.3 5.1 35.9 48.1 41.5 77.6 55.6 25.4 33.2 38.9 23.7 24.7 95.7 51.6 26.4 31.8 27.8 20.5 27.7 51.4 28.0 45.5 28.4 34.3 14.2 25.2 23.9 92.4 29.4 62.1 31.2 19.7 30.2 49.1 95.8 22.8 13.0 44.1 17.1 19.5 33.6 22.5 25.9 34.1 22.2 23.1 66.8 90.8 25.0 17.8 55.4 72.3 24.9 14.8 12.6 46.4 11.3 25.3 32.1 25.2 67.8 17.8 25.0 50.7 65.7 58.9 26.2 92.1 44.1 48.7 33.6 32.8 58.2 63.4 75.0 4.5 3.2 6.1 2.7 4.0 1.7 2.8 2.0 2.2 1.9 2.4 1.3 1.9 12.2 2.6 2.6 3.7 3.5 2.0 38.6 53.3 46.7 56.7 39.2 46.8 60.3 53.5 56.4 45.8 61.3 77.6 20.5 9.6 23.0 17.0 47.2 19.6 70.3 9.9 10.8 11.9 15.3 13.7 10.3 11.5 10.7 5.5 204.3 17.3 43.5 34.2 1.9 7.8 6.0 14.5 45.3 28.9 7.2 19.8 36.0 7.7 24.8 22.2 35.7 28.1 22.1 24.1 23.2 15.8 74.8 8.4 26.0 14.8 8.2 68.5 91.0 13.6 12.5 103.6 44.4 49.6 65.4 11.1 66.9 40.7 112.8 12.4 18.2 17.0 37.2 40.7 10.9 3.2 9.6 98.8 6.6 16.1 24.6 8.5 14.3 10.5 18.0 14.4 47.0 18.9 17.1 46.9 N4BP2L1 CG018 ENSG00000139597 "NEDD4 binding protein 2 like 1" Q5TBK1 13 32400723-32428311 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 23.8;JURKAT: 22.2;NB-4: 61.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038971, HPA057219" Approved Approved Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 24: NB-4 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "HPA038971: AB_10673408, HPA057219: " "unprognostic (2.66e-3)" "unprognostic (2.38e-3)" "unprognostic (3.63e-2)" "unprognostic (5.32e-2)" "unprognostic (5.09e-2)" "unprognostic (3.40e-2)" "prognostic favorable (3.11e-4)" "unprognostic (6.91e-3)" "unprognostic (2.30e-1)" "unprognostic (9.37e-2)" "unprognostic (2.30e-2)" "unprognostic (1.20e-3)" "unprognostic (4.56e-2)" "unprognostic (1.04e-1)" "unprognostic (2.30e-1)" "unprognostic (3.29e-2)" "unprognostic (2.57e-3)" 24.8 11.9 34.0 14.9 33.8 49.5 26.9 32.9 41.1 23.7 32.3 20.3 15.6 19.5 16.1 11.2 26.3 12.6 12.4 34.2 36.2 15.4 85.6 30.2 26.6 29.0 31.1 45.2 20.3 8.6 37.1 13.5 28.4 21.7 14.6 7.9 12.4 11.6 13.8 27.5 21.1 13.0 28.9 30.1 13.8 4.4 37.2 32.0 17.0 9.7 17.9 16.6 20.5 32.7 0.9 0.3 1.3 0.5 5.0 4.0 0.4 0.6 2.2 1.2 2.0 3.8 5.1 10.3 1.4 1.1 3.7 0.1 3.7 0.3 1.6 15.5 2.3 23.8 1.4 11.4 7.8 9.0 1.4 2.8 0.8 1.0 1.0 9.0 0.8 22.2 0.0 18.3 1.0 0.8 18.6 61.4 1.9 0.0 0.5 17.5 0.6 8.8 4.9 1.8 3.4 4.2 3.7 0.1 1.7 2.4 0.5 16.8 0.4 0.5 0.3 0.3 0.1 10.4 6.6 0.5 0.6 3.4 0.7 59.0 49.3 13.9 18.0 47.2 15.9 28.6 17.5 22.4 43.7 33.0 23.9 20.8 12.5 32.1 34.4 56.0 27.9 36.7 34.0 33.8 32.9 41.1 34.2 36.2 29.0 31.1 28.4 28.9 37.2 32.7 46.1 44.8 27.6 53.2 51.4 30.1 29.6 8.7 23.9 10.6 26.6 22.6 4.3 17.2 16.5 5.5 0.0 22.3 74.8 5.5 9.8 15.0 22.5 23.0 5.7 36.1 37.9 25.5 71.7 8.5 1.1 26.2 6.1 4.8 8.8 16.0 21.0 67.2 22.5 0.0 60.4 9.2 24.4 46.6 102.7 22.7 27.4 54.6 30.2 40.3 110.2 7.2 47.4 72.9 43.4 4.4 12.5 22.2 38.4 24.5 25.8 9.8 8.1 2.2 78.9 48.9 40.4 1.4 2.8 15.2 35.4 10.4 44.0 2.5 12.9 16.5 NAA16 "FLJ22054, MGC40612, NARG1L, PRO2435" ENSG00000172766 "N-alpha-acetyltransferase 16, NatA auxiliary subunit" Q6N069 13 41311267-41377030 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 23.5;pancreas: 20.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA039761, HPA040157" Approved Enhanced Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Cytosol "HPA039761: AB_10795112, HPA040157: AB_10793917" "unprognostic (2.09e-2)" "unprognostic (2.86e-2)" "unprognostic (2.95e-1)" "unprognostic (1.04e-2)" "unprognostic (2.66e-2)" "unprognostic (4.45e-2)" "unprognostic (1.60e-1)" "unprognostic (4.47e-3)" "unprognostic (1.09e-2)" "unprognostic (2.90e-1)" "unprognostic (3.04e-2)" "unprognostic (3.50e-2)" "unprognostic (1.36e-2)" "unprognostic (7.94e-2)" "unprognostic (5.81e-2)" "unprognostic (1.58e-1)" "unprognostic (3.34e-2)" 3.2 2.7 1.8 5.0 2.1 23.5 3.9 4.9 2.2 5.0 1.6 2.8 4.3 6.3 2.7 4.2 4.3 3.5 2.4 1.5 2.4 3.1 2.9 3.7 6.5 1.8 2.0 5.9 20.5 3.5 1.9 3.8 2.0 4.7 3.2 5.9 3.9 3.8 4.4 4.1 4.1 3.7 1.1 4.5 4.8 7.5 2.2 5.9 3.7 4.5 4.0 3.9 3.5 3.4 7.3 6.0 14.9 10.8 5.1 6.5 5.7 8.9 7.4 8.6 7.5 7.1 5.6 12.1 4.1 7.2 3.5 10.0 7.7 5.7 10.5 7.5 15.5 15.0 6.3 7.2 5.5 16.8 9.7 4.5 4.2 3.6 6.8 5.8 8.6 11.7 6.8 6.5 5.6 6.0 17.5 4.8 12.6 10.1 8.1 12.9 6.1 10.1 6.8 6.6 5.0 11.6 8.0 7.7 3.3 8.6 4.7 9.3 6.2 5.8 4.9 9.3 7.0 4.5 5.4 14.0 7.5 7.2 7.1 4.4 1.5 3.1 2.3 0.8 2.1 1.0 2.6 2.4 0.8 1.6 4.5 4.7 0.8 3.4 1.2 1.6 2.0 1.3 1.8 2.1 4.9 2.2 1.5 2.4 1.8 2.0 2.0 1.1 2.2 3.4 15.0 9.6 16.7 34.0 19.6 17.7 21.9 9.5 18.8 27.9 10.3 10.2 12.0 10.0 12.4 9.2 14.6 8.8 20.2 5.6 1.9 12.5 17.9 17.2 26.7 16.7 7.7 15.4 53.5 20.5 7.8 18.8 19.9 22.1 3.8 18.9 13.6 8.7 19.1 38.7 66.9 5.5 4.1 8.5 11.7 26.3 30.1 14.3 14.2 45.0 12.0 11.3 21.6 68.9 57.1 13.1 6.9 19.9 28.3 20.0 7.3 7.0 17.3 33.6 19.7 17.0 24.7 39.2 28.8 17.0 14.6 2.9 31.7 17.1 9.7 21.2 NAA20 "dJ1002M8.1, NAT3, NAT5" ENSG00000173418 "N-alpha-acetyltransferase 20, NatB catalytic subunit" P61599 20 20017310-20033655 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 399.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063344 Supported Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA063344: AB_2684991" "unprognostic (2.94e-2)" "unprognostic (1.14e-1)" "unprognostic (7.14e-2)" "unprognostic (2.59e-1)" "unprognostic (1.89e-1)" "prognostic unfavorable (1.96e-4)" "unprognostic (2.00e-2)" "unprognostic (1.11e-2)" "unprognostic (2.40e-1)" "unprognostic (6.18e-2)" "unprognostic (9.30e-2)" "unprognostic (3.85e-1)" "unprognostic (2.93e-1)" "unprognostic (1.72e-1)" "unprognostic (2.13e-1)" "unprognostic (2.28e-1)" "unprognostic (1.32e-1)" 50.4 53.3 38.9 34.8 40.6 46.5 65.3 41.6 51.6 40.8 54.0 41.9 27.9 41.7 54.2 113.5 41.6 32.6 61.7 40.2 42.9 85.2 82.5 40.2 37.3 40.9 41.3 33.0 62.7 103.9 26.7 53.0 41.9 43.5 42.8 49.6 47.1 46.9 84.9 38.2 33.9 46.2 42.3 31.8 42.1 66.6 41.5 37.1 59.7 73.6 51.0 51.3 44.1 44.5 212.7 139.9 50.1 69.4 95.0 116.6 67.7 149.2 100.3 132.1 123.8 67.0 137.7 108.4 80.6 113.6 125.5 156.3 85.8 233.2 153.2 51.4 75.7 79.4 49.6 132.6 141.2 102.2 65.9 122.4 182.1 132.8 153.9 93.2 139.7 80.4 126.7 115.7 157.6 177.2 128.6 149.9 37.9 181.5 180.7 69.8 191.9 148.3 190.0 70.4 84.1 62.2 81.9 254.1 170.7 42.5 145.4 171.1 113.7 106.6 75.4 137.8 153.8 130.0 171.9 116.9 66.5 76.2 76.7 39.7 86.2 70.1 55.5 97.5 83.6 63.3 65.9 65.4 92.9 56.6 63.5 75.0 12.5 70.3 81.8 77.7 75.6 100.6 38.9 40.6 41.6 51.6 40.2 42.9 40.9 41.3 41.9 42.3 41.5 44.5 60.5 67.3 42.2 17.0 44.9 108.7 113.6 312.4 45.5 52.9 62.9 75.2 73.1 77.2 147.8 104.8 25.0 111.8 51.4 32.6 230.9 194.0 399.9 99.5 87.6 77.4 41.3 28.8 18.0 169.0 102.2 66.4 31.1 75.8 51.3 46.5 50.3 72.9 255.9 69.0 22.7 43.8 164.8 66.8 56.1 60.5 69.9 68.6 71.2 31.9 100.1 91.5 58.7 16.1 25.2 198.0 37.1 74.9 44.2 184.5 45.7 242.6 199.9 60.7 39.5 75.8 90.8 354.2 58.3 122.5 118.8 85.5 40.8 99.5 54.2 141.7 NAA30 "C14orf35, FLJ35355, MAK3, Mak3p, NAT12" ENSG00000139977 "N-alpha-acetyltransferase 30, NatC catalytic subunit" Q147X3 14 57390544-57415906 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 107.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057824 Uncertain Supported Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA057824: AB_2683539" "unprognostic (5.13e-2)" "unprognostic (7.59e-2)" "unprognostic (1.09e-1)" "unprognostic (1.52e-2)" "unprognostic (5.22e-2)" "unprognostic (6.31e-2)" "unprognostic (1.84e-2)" "unprognostic (5.44e-2)" "unprognostic (2.59e-1)" "unprognostic (1.12e-1)" "unprognostic (1.67e-1)" "unprognostic (5.21e-2)" "prognostic favorable (1.25e-8)" "unprognostic (1.77e-1)" "unprognostic (1.67e-1)" "unprognostic (5.75e-3)" "unprognostic (1.63e-1)" 9.6 7.7 9.7 7.2 11.3 15.0 9.6 10.6 11.8 7.8 6.5 8.4 9.9 9.1 7.1 11.3 7.4 7.1 14.2 11.6 11.6 12.4 16.7 6.4 9.0 8.6 9.3 14.9 9.0 12.5 5.7 13.4 9.2 10.1 7.9 12.0 8.0 10.1 31.8 8.3 8.7 10.1 9.3 8.3 7.0 18.5 12.4 9.0 10.6 27.3 9.1 8.2 6.0 9.4 19.4 18.2 10.2 16.7 16.8 21.9 17.1 22.1 21.3 16.5 15.0 16.5 13.9 14.1 19.0 18.4 12.5 20.1 18.5 14.3 27.4 24.7 9.4 11.4 10.1 14.5 17.5 23.1 12.8 15.0 20.7 15.0 24.9 18.4 25.8 17.3 11.3 13.6 22.1 22.1 19.5 13.4 11.0 17.8 20.0 15.3 29.4 11.0 16.9 17.4 21.8 11.5 18.7 18.3 23.0 18.2 23.6 11.9 22.7 25.7 27.0 14.2 14.3 10.1 13.2 16.9 17.1 11.5 18.7 0.8 0.4 0.2 1.2 0.9 1.2 1.0 1.1 1.8 0.3 1.1 1.2 1.2 0.2 2.4 2.8 0.6 1.7 0.4 9.7 11.3 10.6 11.8 11.6 11.6 8.6 9.3 9.2 9.3 12.4 9.4 11.8 9.6 6.3 10.1 16.7 41.0 11.8 8.6 25.0 13.5 16.5 10.9 34.9 17.2 8.0 3.7 18.8 18.3 20.1 11.6 9.8 12.5 107.1 9.0 13.1 17.0 21.0 9.0 20.3 11.6 15.6 13.1 12.8 10.8 7.0 14.9 11.0 25.5 9.9 10.1 20.3 13.7 6.1 13.2 12.1 37.6 13.7 8.2 23.2 10.3 9.9 13.3 8.2 16.6 18.9 14.5 13.8 13.5 18.1 18.9 13.6 17.9 9.5 15.3 19.7 13.3 15.4 69.2 20.5 25.5 41.2 22.2 17.0 13.3 12.6 16.7 NAALADL1 ENSG00000168060 "N-acetylated alpha-linked acidic dipeptidase like 1" Q9UQQ1 11 65044818-65058553 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "intestine: 99.3" "Cell type enriched" "Detected in many" 11 "Proximal enterocytes: 588.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 182.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "ASC TERT1: 5.8;fHDF/TERT166: 7.8;HHSteC: 20.2;HSkMC: 13.5;SCLC-21H: 10.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA047123 Enhanced Uncertain Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 9: Intestine - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" Cytosol "HPA047123: AB_2679942" "unprognostic (2.98e-2)" "unprognostic (2.06e-1)" "unprognostic (1.58e-1)" "unprognostic (8.76e-2)" "unprognostic (1.70e-1)" "unprognostic (1.28e-3)" "unprognostic (1.36e-1)" "unprognostic (1.40e-1)" "unprognostic (1.89e-2)" "unprognostic (1.38e-1)" "unprognostic (3.03e-1)" "unprognostic (2.18e-1)" "unprognostic (1.75e-4)" "unprognostic (2.10e-3)" "unprognostic (3.22e-2)" "unprognostic (1.45e-1)" "unprognostic (4.80e-2)" 13.9 3.2 4.4 6.6 4.1 21.1 12.1 4.7 6.0 23.5 7.0 18.4 19.8 18.8 4.6 7.3 15.2 9.4 10.5 3.9 4.1 7.4 2.6 10.9 10.9 4.7 4.3 16.6 2.3 2.0 6.0 2.3 4.6 13.8 7.1 1.9 4.9 11.5 2.7 5.4 99.3 10.5 4.6 15.3 8.2 8.7 4.4 3.4 5.7 4.1 6.9 12.7 14.5 4.0 0.0 0.0 0.1 0.2 0.5 5.8 1.0 2.3 0.0 2.8 1.3 0.0 0.0 0.1 0.0 7.8 0.0 0.0 0.0 0.2 0.1 0.9 0.4 0.0 0.2 3.5 20.2 0.0 0.0 13.5 0.0 2.7 0.0 0.1 3.6 0.1 0.0 0.3 0.0 0.2 0.2 0.7 0.0 0.1 0.1 0.1 0.0 1.0 0.2 0.0 10.5 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.8 0.0 0.1 0.1 182.0 21.2 35.9 29.6 14.6 15.8 25.7 23.8 14.8 16.3 29.8 27.0 15.0 3.7 80.2 8.8 0.7 45.2 24.6 4.4 4.1 4.7 6.0 3.9 4.1 4.7 4.3 4.6 4.6 4.4 4.0 19.1 0.0 0.0 0.0 8.0 3.6 3.4 5.6 6.2 2.0 0.8 9.1 1.8 1.5 0.4 0.0 0.0 0.2 9.8 31.3 3.9 0.1 0.8 0.4 5.8 11.1 1.2 2.5 0.3 0.8 0.3 11.4 1.1 0.2 19.7 4.3 16.8 0.4 2.8 10.1 0.4 21.0 2.0 5.6 5.7 2.6 11.8 5.2 16.0 1.0 17.3 12.2 41.2 1.0 0.1 0.2 50.0 18.0 1.1 0.5 588.6 0.5 0.5 0.9 0.0 8.3 11.1 1.6 3.5 1.3 3.3 0.4 11.1 3.9 11.8 0.4 NACA NACA1 ENSG00000196531 "Nascent polypeptide associated complex subunit alpha" "E9PAV3, Q13765" 12 56712305-56731628 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport" "Activator, Chaperone, DNA-binding" Allergen "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA073152, HPA073648" Approved Cytosol NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Cytosol "HPA073152: AB_2686575, HPA073648: AB_2686621" "unprognostic (3.35e-2)" "unprognostic (9.98e-3)" "unprognostic (1.56e-1)" "unprognostic (2.30e-3)" "unprognostic (4.03e-2)" "unprognostic (2.81e-1)" "unprognostic (1.24e-3)" "unprognostic (1.55e-1)" "unprognostic (3.92e-2)" "unprognostic (2.95e-2)" "unprognostic (5.64e-2)" "unprognostic (8.45e-2)" "prognostic unfavorable (4.58e-11)" "unprognostic (9.47e-2)" "unprognostic (6.28e-2)" "unprognostic (7.00e-2)" "unprognostic (9.79e-2)" 1348.3 1065.0 446.1 607.2 455.9 1524.0 1460.8 456.4 614.8 1642.2 421.9 1252.3 618.6 1067.1 1084.0 1511.9 1216.9 545.1 946.9 431.4 473.1 1038.4 893.7 839.1 1026.5 465.7 442.5 2391.0 1384.8 764.5 811.6 607.7 469.4 1139.7 845.2 453.0 1016.0 699.0 1192.4 1706.1 890.4 689.9 492.3 901.9 1035.1 364.0 450.6 1043.6 918.0 376.8 1432.0 1183.1 1447.1 485.1 1128.5 1333.7 1555.7 1198.7 1795.5 3053.1 1489.5 1117.9 1619.4 1509.9 1051.6 1602.0 1220.7 2014.8 1191.0 1019.4 599.8 963.6 1324.0 1814.9 1600.2 1002.6 2111.7 1463.4 890.3 1640.8 1607.2 2139.1 899.1 2430.3 2204.4 1226.9 2477.6 2669.6 1628.2 1184.8 1896.0 2594.7 1445.5 1118.9 1341.7 2670.1 1528.3 1072.6 1440.8 1543.1 1268.7 2180.1 2124.9 1157.6 1130.2 1197.4 835.8 1977.1 1774.5 1027.8 2109.8 2398.2 1085.4 770.4 933.2 834.0 1127.0 1217.9 1475.1 1768.0 1134.0 1422.3 997.9 462.6 987.0 503.8 581.4 1371.7 851.7 969.7 823.0 726.5 1006.8 812.1 941.6 834.7 350.2 748.7 1842.6 1082.7 944.3 1951.8 446.1 455.9 456.4 614.8 431.4 473.1 465.7 442.5 469.4 492.3 450.6 485.1 1444.2 445.5 645.8 38.8 1822.8 2027.4 2219.5 2022.2 2405.1 325.2 2494.6 5365.8 722.7 1159.6 1095.8 395.4 66.7 1867.2 2037.7 656.8 1778.5 1368.9 701.0 899.4 1625.1 1206.0 647.6 1213.0 31.4 2023.3 2894.2 1085.3 649.4 1079.9 735.9 1600.7 993.4 881.6 1594.4 183.4 35.5 1461.3 801.5 1436.7 1664.7 589.5 2409.8 1430.9 1239.8 40.3 2261.1 1195.0 1528.3 26.7 35.1 1574.8 1306.2 1431.2 1160.8 2248.0 1444.7 2734.4 523.2 455.2 802.0 1977.5 1718.3 542.4 479.1 2363.5 2231.6 2323.4 1549.8 2175.1 1762.0 2618.2 NACA2 "MGC71999, NACAL" ENSG00000253506 "Nascent polypeptide associated complex subunit alpha 2" Q9H009 17 61590421-61591219 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 33 "testis: 64.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 143.4;Early spermatids: 418.0;Late spermatids: 155.3;Spermatocytes: 233.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 3.2;SK-MEL-30: 2.0" "HPA073152, HPA073648" Approved Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA073152: AB_2686575, HPA073648: AB_2686621" "unprognostic (2.37e-1)" "unprognostic (1.50e-2)" "unprognostic (9.59e-2)" "unprognostic (5.33e-3)" "unprognostic (3.37e-1)" "unprognostic (1.45e-1)" "unprognostic (8.14e-3)" "unprognostic (4.91e-2)" "unprognostic (3.51e-2)" "unprognostic (1.18e-2)" "unprognostic (7.80e-2)" "unprognostic (2.08e-1)" "unprognostic (1.80e-2)" "unprognostic (6.88e-2)" "unprognostic (7.53e-3)" "unprognostic (5.45e-3)" "unprognostic (3.09e-3)" 1.0 0.9 0.0 0.5 0.0 0.2 1.0 0.0 0.0 1.1 0.0 0.9 0.1 0.7 0.0 1.1 0.7 0.0 0.9 0.0 0.0 1.1 0.8 0.7 0.4 0.0 0.0 1.9 1.1 0.0 0.7 0.1 0.0 1.0 0.1 0.0 0.8 0.0 1.0 1.4 0.7 0.1 0.0 0.7 0.8 64.1 0.0 0.0 0.8 0.0 0.2 0.7 1.0 0.0 0.3 0.0 0.3 0.3 0.1 0.2 0.9 0.0 0.3 0.1 0.2 0.2 0.1 0.0 0.5 0.0 0.1 0.1 0.0 0.1 0.2 0.2 0.1 0.1 0.3 0.3 0.1 0.1 0.3 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.1 1.0 0.0 0.1 0.4 3.2 0.7 0.0 0.1 0.4 0.2 1.1 0.1 0.0 0.3 0.7 0.2 0.4 2.0 0.0 0.8 1.1 0.0 0.1 0.4 0.6 0.3 0.3 0.3 0.3 0.4 0.2 0.2 0.1 0.3 0.1 0.2 0.7 0.3 0.4 0.3 0.3 0.4 0.4 0.4 0.4 0.0 0.3 0.7 0.4 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 2.0 11.2 69.3 60.6 15.0 0.0 0.7 2.2 3.2 143.4 35.8 5.2 1.8 0.0 17.5 11.7 2.9 86.1 0.3 418.0 0.5 1.1 17.6 3.6 2.7 3.4 0.8 24.1 18.5 0.0 0.6 0.0 0.7 26.4 15.1 14.5 0.0 4.0 9.1 10.2 50.7 66.3 155.3 33.8 8.2 46.2 1.0 23.7 1.5 23.7 1.5 3.5 0.6 11.1 11.3 0.0 48.1 8.1 62.1 2.9 0.9 13.1 63.8 107.3 233.8 11.4 0.0 79.3 24.1 16.3 1.1 11.8 42.9 NAPA ENSG00000105402 "NSF attachment protein alpha" P54920 19 47487637-47515091 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010100, HPA046149, HPA050196" Approved Uncertain Cytosol NA NA 2200000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "CAB010100: AB_628263, HPA046149: AB_2679557, HPA050196: AB_2681048" "unprognostic (9.83e-2)" "unprognostic (9.43e-3)" "unprognostic (1.12e-2)" "unprognostic (1.76e-3)" "unprognostic (9.72e-2)" "unprognostic (3.08e-2)" "unprognostic (2.15e-1)" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (5.61e-2)" "unprognostic (2.42e-3)" "unprognostic (1.09e-3)" "prognostic favorable (4.26e-9)" "unprognostic (4.04e-2)" "unprognostic (4.17e-2)" "unprognostic (8.55e-2)" "unprognostic (2.90e-2)" 83.0 147.5 104.8 56.8 112.1 115.2 83.6 112.4 146.1 87.2 89.8 79.5 61.9 102.0 54.5 122.7 86.0 63.7 112.9 125.1 102.5 98.6 153.2 79.8 57.0 120.9 99.8 66.4 92.0 101.1 96.5 56.9 119.3 105.1 50.8 83.7 124.3 94.6 180.2 131.9 62.4 72.6 97.3 66.4 83.6 79.3 111.2 85.2 74.6 116.8 53.1 76.7 85.7 112.8 73.1 99.3 48.1 85.3 100.4 80.9 36.7 78.1 98.7 189.3 229.1 76.1 44.3 55.8 41.5 110.4 119.1 56.3 77.7 98.1 72.8 89.2 84.6 70.1 88.5 93.6 256.9 80.6 124.5 122.0 70.2 77.0 47.6 38.1 92.1 74.9 67.0 150.0 123.7 66.2 115.7 284.6 40.5 110.7 75.7 79.8 42.2 82.6 149.6 133.5 174.9 67.6 101.0 126.4 76.6 43.8 98.9 136.9 91.0 97.4 51.3 83.9 93.6 94.5 143.7 76.9 176.3 89.5 102.5 196.4 165.0 313.1 96.1 189.8 81.3 68.7 82.9 94.3 132.3 70.3 84.8 85.3 187.9 111.1 201.1 209.9 112.2 209.4 104.8 112.1 112.4 146.1 125.1 102.5 120.9 99.8 119.3 97.3 111.2 112.8 59.1 12.8 41.5 19.9 48.6 63.3 91.1 73.5 92.2 55.1 69.5 63.5 3.8 72.9 44.5 51.5 27.1 106.4 73.3 89.1 178.1 110.9 44.2 40.8 37.5 49.3 83.6 89.9 30.5 99.8 69.0 48.0 94.8 70.0 64.7 23.8 39.7 89.6 131.1 35.3 21.7 62.6 99.7 58.4 69.1 37.4 42.9 87.7 97.8 14.0 79.1 76.7 66.9 11.1 21.8 100.2 69.8 46.3 92.9 50.5 80.3 99.0 20.1 47.3 92.1 44.3 63.0 119.0 73.7 97.4 68.6 228.9 58.0 61.7 50.7 75.5 NAPB "SNAP-BETA, SNAPB" ENSG00000125814 "NSF attachment protein beta" Q9H115 20 23374519-23421519 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "brain: 126.9;retina: 154.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 203.4;Cone photoreceptor cells: 66.7;Excitatory neurons: 68.8;Horizontal cells: 67.3;Late spermatids: 75.6;Rod photoreceptor cells: 84.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "SCLC-21H: 31.8;U-937: 32.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037225, CAB037227, HPA046149, HPA050196" Supported Uncertain Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" Cytosol "CAB037225: AB_477555, CAB037227: AB_477554, HPA046149: AB_2679557, HPA050196: AB_2681048" "unprognostic (3.89e-1)" "unprognostic (2.71e-1)" "unprognostic (5.95e-2)" "unprognostic (1.05e-1)" "unprognostic (2.54e-2)" "unprognostic (3.92e-2)" "unprognostic (1.32e-3)" "unprognostic (1.25e-1)" "unprognostic (4.71e-2)" "unprognostic (6.37e-2)" "unprognostic (4.46e-3)" "unprognostic (7.52e-3)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.42e-1)" "unprognostic (2.31e-1)" "unprognostic (1.12e-1)" "unprognostic (4.60e-2)" 6.7 24.3 89.3 5.2 98.3 10.6 6.5 53.4 126.9 10.7 8.1 10.0 5.0 7.4 8.8 7.3 9.4 4.8 7.1 102.4 92.6 8.3 7.3 8.3 5.8 90.7 42.4 13.3 6.6 7.8 18.5 8.7 90.5 8.0 6.7 154.1 6.9 5.9 6.4 7.7 8.0 6.0 38.0 8.7 7.1 8.9 48.3 6.1 9.0 3.1 4.4 8.2 9.5 84.1 5.8 3.7 6.0 6.2 6.6 6.1 8.5 7.4 4.0 5.9 5.1 4.4 5.1 8.6 8.6 4.4 4.3 7.3 7.8 5.0 7.1 2.8 5.8 9.4 5.4 10.5 7.8 7.0 5.4 6.1 6.5 4.2 5.2 5.4 4.4 8.6 8.0 11.0 9.4 4.0 7.2 6.4 2.6 4.7 6.7 4.8 4.9 6.5 7.7 6.2 31.8 10.1 4.3 4.1 7.1 8.7 4.2 4.4 5.2 5.6 4.1 6.2 5.4 8.0 6.7 3.8 2.9 32.9 5.7 2.5 0.5 0.0 1.9 0.5 0.6 0.6 0.8 0.9 0.8 1.2 0.7 1.2 0.6 0.6 0.9 0.6 1.0 0.9 89.3 98.3 53.4 126.9 102.4 92.6 90.7 42.4 90.5 38.0 48.3 84.1 4.1 12.8 6.5 30.0 6.6 8.7 5.6 4.1 6.2 203.4 4.2 2.9 6.0 7.2 6.8 14.7 66.7 7.0 5.9 3.6 0.0 3.3 39.9 4.4 5.8 7.5 10.2 2.5 68.8 1.4 5.4 7.4 3.1 3.8 11.4 14.3 9.7 5.5 5.2 67.3 63.8 2.7 14.2 7.2 10.2 75.6 9.0 4.0 10.6 24.4 7.9 20.5 15.5 38.2 37.2 2.9 1.8 9.1 4.7 6.4 9.2 3.6 6.1 84.8 6.6 5.4 5.5 13.4 11.2 3.9 8.4 6.2 6.5 9.3 4.2 4.6 NAPEPLD "C7orf18, FMP30, NAPE-PLD" ENSG00000161048 "N-acyl phosphatidylethanolamine phospholipase D" Q6IQ20 7 103099776-103149560 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Early spermatids: 128.0;Excitatory neurons: 99.2;Oligodendrocyte precursor cells: 126.7;Oligodendrocytes: 193.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019832, HPA024338" Approved Approved Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 18: U-2197 - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "HPA019832: AB_1844422, HPA024338: AB_2671533" "unprognostic (3.62e-1)" "unprognostic (1.86e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-1)" "unprognostic (7.58e-2)" "unprognostic (1.05e-3)" "unprognostic (1.02e-2)" "unprognostic (6.39e-3)" "unprognostic (2.70e-2)" "unprognostic (1.20e-1)" "unprognostic (2.81e-2)" "unprognostic (3.21e-1)" "prognostic favorable (7.32e-6)" "unprognostic (8.83e-2)" "unprognostic (1.19e-1)" "unprognostic (1.42e-1)" "unprognostic (2.41e-2)" 2.0 4.6 1.6 3.6 3.7 2.0 1.7 1.5 4.2 3.6 0.0 7.7 14.5 3.6 2.2 1.9 5.3 5.9 4.0 1.7 0.0 14.9 7.4 3.0 3.3 0.4 1.1 8.6 3.5 6.0 1.5 2.2 0.8 4.5 7.5 4.8 1.7 3.4 2.4 3.1 9.7 3.0 0.5 6.4 9.9 6.7 2.5 3.0 8.2 2.4 2.7 3.5 1.8 9.2 6.9 7.4 5.1 4.3 4.9 4.9 0.9 5.4 3.1 1.6 3.3 2.7 6.3 5.2 7.7 1.7 6.3 5.6 3.3 0.5 3.8 6.9 6.0 1.9 4.1 1.5 1.1 3.3 2.2 2.8 0.9 1.6 0.0 12.5 3.5 3.5 2.0 4.8 5.0 2.2 5.1 2.4 4.7 9.4 9.7 3.6 2.8 1.9 10.5 2.9 3.8 4.6 10.7 3.7 2.7 3.1 2.4 4.4 4.6 7.7 4.0 17.8 4.9 6.8 8.6 3.7 7.6 2.9 14.8 0.1 1.9 3.7 2.7 2.9 2.3 4.6 3.1 3.4 2.1 4.5 4.4 3.2 0.2 1.5 1.9 1.7 2.9 1.4 1.6 3.7 1.5 4.2 1.7 0.0 0.4 1.1 0.8 0.5 2.5 9.2 4.6 19.2 10.0 38.8 13.2 6.6 5.5 5.3 9.6 78.1 5.7 5.0 12.3 17.2 6.8 53.3 52.1 8.1 5.6 37.5 9.8 5.3 128.0 27.5 10.7 5.2 13.8 36.6 99.2 2.6 4.0 7.3 41.3 42.9 4.5 12.0 4.6 19.1 3.9 50.5 56.7 27.0 4.1 5.5 1.8 43.8 31.7 4.4 14.2 21.5 7.2 16.1 18.6 126.7 193.3 5.0 28.7 33.4 10.6 6.5 46.5 32.6 3.0 35.4 6.6 7.8 6.3 21.1 12.2 3.1 2.8 2.9 8.1 18.9 26.8 7.8 NARS1 NARS ENSG00000134440 "Asparaginyl-tRNA synthetase 1" O43776 18 57600656-57622213 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 221.3;Cytotrophoblasts: 116.0;Extravillous trophoblasts: 85.2;Hofbauer cells: 117.4;Syncytiotrophoblasts: 158.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034257, HPA040017" Enhanced Supported Cytosol NA NA 76000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 24: Non-specific - Transcription regulation" Cytosol "CAB034257: AB_2151043, HPA040017: AB_2676801" "unprognostic (9.85e-2)" "unprognostic (1.88e-1)" "unprognostic (3.86e-3)" "unprognostic (1.68e-1)" "unprognostic (2.61e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.23e-7)" "unprognostic (1.78e-1)" "unprognostic (1.48e-1)" "unprognostic (1.62e-2)" "unprognostic (1.98e-1)" "unprognostic (8.82e-2)" "prognostic favorable (1.73e-7)" "unprognostic (1.24e-2)" "unprognostic (1.30e-1)" "unprognostic (1.10e-1)" "unprognostic (1.51e-1)" 67.2 65.9 51.7 62.1 53.8 48.8 68.3 58.8 77.7 57.5 60.1 108.7 87.3 52.7 66.5 64.2 58.5 56.0 94.8 53.4 60.4 135.1 75.5 51.7 52.8 59.6 55.6 45.4 63.1 125.3 33.2 56.1 58.5 68.4 99.5 68.2 68.8 65.4 127.2 49.6 72.0 65.5 55.9 46.8 79.4 32.7 63.7 59.1 95.0 130.6 67.3 78.0 41.9 60.1 215.1 133.2 129.6 199.1 172.8 130.7 202.5 302.5 161.7 179.2 215.4 100.3 97.0 270.7 136.2 208.7 172.1 241.7 211.0 191.6 259.0 127.5 75.5 217.8 105.4 171.8 299.9 433.0 212.5 146.0 331.2 233.8 245.8 130.6 154.6 169.4 246.5 201.6 200.9 86.2 172.4 111.9 189.6 145.1 118.6 139.8 154.5 229.9 340.3 224.4 140.9 147.6 153.1 184.0 309.4 137.3 108.8 242.6 179.7 190.5 127.7 78.8 215.8 449.1 559.2 260.3 175.1 285.7 227.7 50.9 108.5 38.8 41.8 92.6 50.9 52.6 43.3 44.7 71.7 51.4 58.2 52.6 34.4 43.6 76.8 64.0 49.4 74.9 51.7 53.8 58.8 77.7 53.4 60.4 59.6 55.6 58.5 55.9 63.7 60.1 26.2 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 221.3 0.0 0.0 0.0 0.0 116.0 19.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 85.2 23.1 0.0 0.0 0.0 0.0 0.0 0.0 117.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.0 0.0 158.6 3.5 0.0 0.0 0.0 NCDN "NCDN-1, NCDN-2" ENSG00000020129 Neurochondrin Q9UBB6 1 35557473-35567274 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 424.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 39.7;Inhibitory neurons: 35.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023676 Enhanced Supported Supported Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA023676: AB_1854325" "unprognostic (1.15e-1)" "unprognostic (7.11e-2)" "unprognostic (1.08e-1)" "unprognostic (6.05e-2)" "unprognostic (6.12e-3)" "unprognostic (2.39e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (4.66e-2)" "unprognostic (1.41e-1)" "unprognostic (4.36e-2)" "prognostic favorable (3.73e-4)" "unprognostic (5.91e-3)" "unprognostic (5.34e-3)" "unprognostic (5.88e-3)" "unprognostic (2.87e-1)" "unprognostic (3.24e-2)" "unprognostic (2.23e-2)" 10.7 23.9 197.0 9.4 424.1 4.9 9.8 51.0 360.4 20.5 0.0 16.9 5.3 17.1 6.5 12.1 16.1 9.7 23.1 364.2 118.3 13.4 10.3 11.8 9.6 114.1 115.9 18.9 10.0 10.6 38.7 6.7 112.0 17.2 3.4 21.3 11.0 11.3 14.6 10.1 10.6 9.6 168.3 11.4 14.9 15.3 215.9 7.4 16.6 9.0 6.6 16.2 15.9 191.3 17.3 20.5 16.8 26.6 23.8 29.4 11.6 22.3 22.9 23.0 18.3 20.6 24.8 19.6 21.1 20.7 16.5 26.0 16.6 27.1 8.4 19.2 34.3 24.4 32.2 10.7 33.0 22.3 26.9 28.2 22.2 40.7 16.3 18.9 12.3 11.6 26.9 30.4 18.9 31.0 20.5 14.2 75.7 19.1 35.6 16.6 9.4 25.4 15.6 19.0 20.9 30.0 25.4 23.2 32.1 13.3 22.2 14.4 17.0 29.1 20.9 21.5 30.9 42.4 32.6 14.7 36.3 35.1 27.1 0.0 2.6 0.4 1.6 1.5 2.0 3.7 2.5 2.5 1.5 1.4 3.3 2.9 0.3 1.8 2.6 0.9 1.5 3.8 197.0 424.1 51.0 360.4 364.2 118.3 114.1 115.9 112.0 168.3 215.9 191.3 3.8 3.2 12.0 15.7 1.9 3.4 0.5 4.0 1.8 4.7 5.8 7.1 13.8 2.8 12.6 7.3 0.0 5.6 2.0 2.9 1.9 3.7 2.5 3.9 8.1 4.4 3.6 2.1 39.7 4.4 2.6 6.1 8.6 5.1 3.8 6.5 3.3 4.3 3.5 6.7 35.0 3.5 6.1 6.7 1.0 1.4 6.5 2.6 5.4 12.2 1.7 2.1 2.1 9.5 16.4 3.8 2.1 4.1 6.5 0.6 0.8 4.7 14.7 2.9 0.0 1.7 5.4 5.1 2.2 2.7 3.0 5.6 4.9 8.0 1.7 0.6 NCF2 "NOXA2, p67phox" ENSG00000116701 "Neutrophil cytosolic factor 2" P19878 1 183555562-183590876 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 191.9;lung: 74.6;lymphoid tissue: 78.8" "Group enriched" "Detected in many" 5 "Ductal cells: 68.6;Hofbauer cells: 212.0;Kupffer cells: 137.9;Langerhans cells: 129.5;Macrophages: 194.4;monocytes: 223.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1313.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 26.4;HMC-1: 21.4;hTERT-HME1: 51.6;RPMI-8226: 20.0;U-2 OS: 50.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002327, HPA006040, CAB022160" Enhanced Supported Cytosol NA NA 12000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "CAB022160: , HPA002327: AB_1079550, HPA006040: AB_1854906" "unprognostic (4.97e-2)" "unprognostic (3.48e-2)" "unprognostic (2.40e-2)" "unprognostic (1.22e-3)" "unprognostic (5.83e-3)" "unprognostic (4.04e-2)" "prognostic unfavorable (7.91e-6)" "unprognostic (1.29e-1)" "unprognostic (2.45e-1)" "unprognostic (2.33e-1)" "unprognostic (5.70e-2)" "unprognostic (2.01e-1)" "unprognostic (1.57e-2)" "unprognostic (1.61e-1)" "unprognostic (1.41e-2)" "unprognostic (8.24e-2)" "unprognostic (2.36e-2)" 29.9 5.8 2.7 76.9 3.0 191.9 7.0 3.2 14.6 9.5 4.5 10.4 8.5 4.1 1.6 7.6 8.0 23.8 5.6 2.3 3.9 3.7 12.7 74.6 17.3 6.2 4.2 2.1 4.6 2.8 2.7 39.7 6.8 2.9 12.5 0.8 6.6 3.5 3.7 15.9 12.4 20.4 4.5 78.8 5.8 2.1 12.0 11.3 3.0 11.5 16.9 24.2 5.9 7.8 26.4 0.8 0.0 0.0 0.0 0.0 0.3 1.9 2.4 3.4 1.6 0.2 0.8 3.2 4.3 0.8 0.6 14.3 0.1 19.0 3.1 16.2 0.0 0.0 7.3 6.0 0.0 2.0 21.4 0.0 4.1 3.4 51.6 2.2 0.0 0.1 0.0 5.6 5.8 0.2 0.2 1.1 0.4 1.5 1.5 7.0 2.2 20.0 0.8 0.2 0.0 0.1 0.3 0.1 0.9 1.7 2.8 9.1 1.2 0.1 50.2 0.0 4.9 0.9 1.4 0.6 0.4 10.3 0.0 199.5 489.2 1313.6 1.0 348.8 1.6 14.1 4.0 1.6 246.0 10.8 2.2 1.3 799.7 2.1 326.1 13.5 11.1 298.9 2.7 3.0 3.2 14.6 2.3 3.9 6.2 4.2 6.8 4.5 12.0 7.8 0.7 9.6 15.7 0.0 8.4 5.5 0.2 13.7 1.8 0.3 0.1 0.3 1.3 7.2 17.3 0.0 0.0 1.0 9.6 0.1 3.9 68.6 1.1 1.9 0.5 3.5 0.0 1.7 0.3 3.9 1.1 2.0 0.5 1.3 7.6 0.0 3.3 1.0 212.0 0.0 0.3 0.2 26.4 137.9 129.5 2.9 0.6 194.4 7.2 3.7 223.6 0.0 6.2 0.0 0.2 27.3 2.6 0.0 3.2 0.6 0.0 0.3 32.0 0.7 13.1 0.7 6.8 0.1 0.6 0.6 4.3 1.9 3.7 0.2 0.0 1.2 NCF4 "p40phox, SH3PXD4" ENSG00000100365 "Neutrophil cytosolic factor 4" Q15080 22 36860988-36878017 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 180.2;lymphoid tissue: 162.3" "Cell type enhanced" "Detected in many" "B-cells: 70.9;granulocytes: 74.1;Hofbauer cells: 198.4;Kupffer cells: 85.3;Langerhans cells: 55.8;Macrophages: 85.7;Plasma cells: 68.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 657.3;eosinophil: 750.1;neutrophil: 1235.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 1235.8" "Cell line enhanced" "Detected in some" "HEL: 78.3;HMC-1: 396.0;NB-4: 148.7;REH: 76.5;RPMI-8226: 144.0;THP-1: 137.9;U-937: 76.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010146, HPA036156, HPA057975" Enhanced Enhanced Cytosol NA NA 7800 "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" Cytosol "CAB010146: AB_627989, HPA036156: AB_2674974, HPA057975: AB_2683568" "unprognostic (3.27e-2)" "unprognostic (1.55e-2)" "unprognostic (2.68e-2)" "unprognostic (1.36e-3)" "unprognostic (1.35e-1)" "unprognostic (2.78e-3)" "unprognostic (4.20e-2)" "unprognostic (3.69e-2)" "unprognostic (4.03e-2)" "unprognostic (2.70e-1)" "unprognostic (3.27e-2)" "unprognostic (2.54e-1)" "prognostic unfavorable (7.06e-8)" "unprognostic (3.60e-1)" "unprognostic (2.23e-2)" "unprognostic (1.19e-1)" "unprognostic (2.42e-1)" 29.5 14.4 4.8 43.1 5.0 180.2 12.7 4.9 7.5 4.6 6.4 19.2 11.7 4.5 1.0 7.2 13.9 13.0 9.4 4.9 5.4 8.9 10.1 45.1 39.8 6.8 5.9 3.3 4.1 1.4 5.3 24.3 6.4 7.4 11.8 0.1 10.7 4.5 3.6 4.9 42.6 10.5 5.8 162.3 9.3 1.8 8.6 12.9 8.1 7.1 33.5 18.7 7.2 7.1 1.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 28.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.6 0.0 78.3 0.0 0.0 0.0 12.8 396.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 26.8 0.0 0.8 0.0 148.7 0.0 0.0 0.0 76.5 0.0 144.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 137.9 0.0 0.0 0.2 0.1 0.2 0.5 0.1 23.7 0.1 76.8 0.1 657.3 184.6 750.1 2.3 92.5 9.8 108.2 32.0 6.9 86.1 85.9 1.9 2.1 1235.8 4.4 62.0 100.7 96.3 106.3 4.8 5.0 4.9 7.5 4.9 5.4 6.8 5.9 6.4 5.8 8.6 7.1 1.5 3.2 18.7 0.0 70.9 2.8 2.2 1.3 0.6 0.0 3.1 2.5 2.1 0.0 5.8 1.8 0.0 3.2 21.1 1.3 0.0 0.6 0.2 0.2 0.1 3.6 0.0 28.8 0.0 3.1 16.0 1.8 2.0 0.4 74.1 0.0 1.4 0.7 198.4 0.0 0.0 0.5 2.0 85.3 55.8 1.0 0.6 85.7 14.2 3.7 38.5 0.0 3.1 0.0 0.1 0.9 22.5 0.0 68.2 0.3 0.2 0.2 0.9 0.3 0.0 0.5 1.6 0.0 0.4 0.5 2.3 13.0 17.5 0.7 1.7 4.3 NCKAP1 "HEM2, Nap1, NAP125" ENSG00000061676 "NCK associated protein 1" Q9Y2A7 2 182909115-183038858 "Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020449 Enhanced Approved Cytosol NA NA 60000 "Cluster 2: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Cytosol "HPA020449: AB_1854327" "unprognostic (7.92e-3)" "unprognostic (1.24e-2)" "unprognostic (3.35e-2)" "unprognostic (8.10e-2)" "unprognostic (1.31e-1)" "unprognostic (1.24e-1)" "unprognostic (2.12e-3)" "prognostic unfavorable (9.71e-4)" "unprognostic (5.06e-2)" "unprognostic (1.88e-2)" "prognostic unfavorable (3.81e-4)" "unprognostic (3.48e-2)" "unprognostic (1.92e-1)" "unprognostic (3.44e-2)" "unprognostic (2.41e-1)" "unprognostic (1.36e-1)" "unprognostic (3.61e-2)" 51.5 44.3 48.3 25.6 57.6 1.0 48.7 45.9 58.7 55.0 43.5 59.4 55.9 52.8 52.9 81.3 42.1 42.3 71.8 72.8 47.2 70.6 41.2 40.3 10.3 36.9 46.2 45.0 43.0 88.4 34.0 50.1 41.9 55.4 48.5 58.4 43.2 65.4 89.5 51.1 51.3 74.1 37.9 20.5 57.7 32.1 45.4 15.2 85.4 87.3 24.6 60.8 49.1 44.4 107.1 66.0 99.1 63.6 136.8 132.3 110.2 136.5 123.4 90.6 113.3 102.9 89.2 0.6 89.2 163.1 136.1 99.0 84.6 128.6 150.2 25.7 66.1 23.7 69.4 85.4 140.5 0.2 19.9 99.5 155.4 131.4 213.8 123.7 146.3 6.4 58.7 0.4 173.3 68.5 2.3 0.4 102.1 85.8 112.7 6.9 108.2 0.4 127.9 141.9 72.7 69.3 123.6 97.0 130.0 156.2 52.0 0.7 160.0 153.2 86.1 87.1 84.7 13.4 26.5 0.5 118.6 0.1 79.5 0.4 0.0 0.3 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.0 48.3 57.6 45.9 58.7 72.8 47.2 36.9 46.2 41.9 37.9 45.4 44.4 75.3 48.1 47.1 129.9 2.1 87.2 64.7 50.1 38.1 83.9 54.2 39.9 103.9 48.6 57.0 80.9 70.9 33.1 3.7 52.4 27.4 54.3 4.5 56.4 57.9 82.8 50.4 0.8 174.2 62.0 50.2 62.3 49.5 106.6 14.0 43.8 72.8 42.4 5.3 122.8 143.9 58.8 50.8 5.5 23.1 9.0 78.6 4.6 55.2 72.1 0.7 90.7 6.2 136.7 98.8 95.7 69.8 105.3 1.4 116.8 64.3 66.4 40.2 59.9 59.2 86.1 84.1 42.4 28.7 83.6 112.5 52.1 5.5 55.6 55.5 117.3 NCSTN "APH2, KIAA0253" ENSG00000162736 Nicastrin Q92542 1 160343316-160358952 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Notch signaling pathway" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 147.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021982, HPA054846, HPA070642" Approved Approved Cytosol NA NA 130000 "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "CAB021982: , HPA054846: AB_2682624, HPA070642: AB_2686289" "unprognostic (1.08e-1)" "unprognostic (5.22e-3)" "unprognostic (1.51e-1)" "unprognostic (2.89e-2)" "unprognostic (1.19e-2)" "unprognostic (2.22e-2)" "unprognostic (1.69e-3)" "unprognostic (2.89e-1)" "unprognostic (3.30e-2)" "unprognostic (3.62e-2)" "unprognostic (8.21e-2)" "unprognostic (2.06e-2)" "prognostic unfavorable (7.75e-9)" "unprognostic (1.36e-3)" "unprognostic (3.15e-1)" "unprognostic (3.14e-2)" "unprognostic (4.89e-2)" 51.0 36.6 30.6 42.1 36.1 38.1 43.9 38.5 32.5 52.4 42.0 58.4 80.4 40.3 56.4 35.1 49.7 42.9 50.6 29.9 35.8 59.7 59.3 56.0 38.3 40.0 34.0 51.7 63.8 86.0 30.1 98.7 41.6 45.2 60.9 48.1 60.5 47.3 37.6 38.9 63.5 52.1 37.3 46.2 45.7 41.8 36.4 40.0 63.8 38.4 43.0 45.6 31.5 48.9 52.1 57.4 100.4 82.8 301.0 153.4 108.3 104.0 177.0 95.4 109.9 47.9 140.0 36.6 208.6 209.3 67.1 81.5 47.3 95.9 82.4 56.5 42.3 36.6 70.9 70.0 118.6 82.8 152.0 155.7 92.3 94.3 93.6 207.2 139.9 54.3 66.9 100.2 142.2 34.3 26.8 39.8 82.2 130.6 33.8 35.1 59.9 103.6 130.5 69.9 34.2 75.6 109.1 118.5 70.9 158.0 108.2 186.3 125.5 70.3 46.4 48.8 79.9 130.8 194.4 38.6 106.6 49.8 129.4 71.4 79.0 67.8 27.4 79.0 26.2 31.1 23.5 24.0 75.1 27.8 23.9 23.3 69.2 36.6 79.6 45.1 26.5 52.2 30.6 36.1 38.5 32.5 29.9 35.8 40.0 34.0 41.6 37.3 36.4 48.9 28.0 6.4 9.3 0.0 23.0 10.5 23.8 59.5 15.9 20.0 27.9 23.1 14.6 45.8 42.6 53.3 52.1 107.7 27.8 53.3 7.9 38.9 2.6 19.2 19.7 23.9 20.3 17.2 0.0 27.0 95.7 33.7 17.9 30.2 13.3 25.8 29.6 31.4 58.0 18.5 0.0 31.8 46.8 47.1 18.8 4.7 27.1 33.4 17.8 0.0 31.7 35.0 20.6 0.0 0.0 34.8 33.4 21.1 33.2 15.6 66.1 24.7 28.7 26.3 26.3 23.8 19.6 44.6 35.9 15.5 11.4 147.4 16.5 32.5 29.6 20.5 NDST2 "HSST2, NST2" ENSG00000166507 "N-deacetylase and N-sulfotransferase 2" P52849 10 73801911-73811798 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 13.7;granulocytes: 14.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 110.2" HPA051515 Approved Approved Cytosol NA NA 130000 "Cluster 32: T-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" Cytosol "HPA051515: AB_2681517" "unprognostic (8.84e-2)" "unprognostic (7.57e-2)" "unprognostic (2.53e-2)" "unprognostic (9.43e-3)" "unprognostic (5.69e-1)" "unprognostic (1.07e-2)" "unprognostic (5.83e-3)" "unprognostic (2.16e-2)" "unprognostic (8.19e-2)" "unprognostic (1.61e-2)" "unprognostic (2.23e-5)" "unprognostic (1.49e-2)" "unprognostic (4.08e-7)" "unprognostic (3.71e-2)" "unprognostic (3.69e-2)" "unprognostic (5.93e-2)" "unprognostic (9.06e-2)" 14.9 16.7 11.6 19.6 11.6 53.6 13.3 15.7 14.2 15.7 10.6 13.6 10.7 15.7 11.6 16.8 15.0 15.1 11.4 11.6 11.7 14.4 10.9 17.0 24.6 12.6 11.4 15.8 14.1 18.4 15.8 12.5 11.2 15.6 12.1 14.9 17.7 14.2 8.9 18.8 17.4 15.8 10.4 35.3 13.6 13.6 12.5 31.9 13.3 8.5 23.9 15.3 15.4 11.5 10.0 7.9 16.7 26.2 20.9 23.0 9.1 12.3 24.5 13.4 13.3 4.6 12.4 9.5 7.1 21.8 13.6 11.6 8.1 11.8 9.6 23.4 8.5 9.3 7.0 7.3 36.7 11.8 110.2 22.9 14.5 21.4 22.4 41.1 17.5 17.9 9.2 33.8 16.6 8.1 12.7 13.4 4.5 6.4 36.4 8.5 8.2 5.9 11.5 7.2 5.5 9.0 9.9 23.5 7.5 11.3 18.6 18.6 29.5 6.3 7.8 9.1 8.4 17.4 8.0 11.8 7.2 17.0 5.5 0.7 2.7 1.1 2.7 1.9 3.1 1.2 2.3 2.3 2.0 1.3 2.6 3.4 2.8 1.1 1.7 3.4 1.6 1.8 11.6 11.6 15.7 14.2 11.6 11.7 12.6 11.4 11.2 10.4 12.5 11.5 1.5 0.0 3.0 13.7 5.4 1.3 0.8 0.6 1.2 0.7 4.1 2.3 1.8 0.0 1.8 0.0 0.0 1.4 3.6 4.7 0.0 5.4 7.5 0.8 1.2 1.1 2.4 7.8 7.5 9.6 1.5 1.9 4.6 0.7 14.5 0.3 1.4 4.2 5.2 1.7 7.6 2.6 2.0 8.5 3.1 10.4 0.0 10.8 1.8 2.8 5.4 0.8 0.0 5.0 5.0 7.0 3.2 0.0 10.6 1.3 2.4 7.4 2.7 0.8 0.0 1.4 1.5 2.3 1.7 4.7 1.6 6.2 5.3 0.3 2.2 1.9 NEDD4 "KIAA0093, MGC176705, NEDD4-1, RPF1" ENSG00000069869 "NEDD4 E3 ubiquitin protein ligase" P46934 15 55826922-55993660 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Neurogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 67.6;tongue: 58.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 93.0;Alveolar cells type 2: 116.7;granulocytes: 73.2;Oligodendrocyte precursor cells: 69.9;Respiratory ciliated cells: 75.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001991, HPA039883, CAB072833" Approved Approved Cytosol NA NA 6500 "Cluster 39: Non-specific - mRNA processing" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 11: Alveolar cells - Smell perception" Cytosol "CAB001991: , CAB072833: , HPA039883: AB_10795683" "unprognostic (1.18e-1)" "unprognostic (2.10e-2)" "unprognostic (5.66e-3)" "unprognostic (1.15e-1)" "unprognostic (6.97e-2)" "unprognostic (2.23e-1)" "unprognostic (3.18e-3)" "prognostic unfavorable (5.14e-4)" "unprognostic (1.36e-2)" "unprognostic (1.62e-1)" "unprognostic (4.96e-2)" "unprognostic (1.43e-2)" "prognostic unfavorable (3.74e-6)" "unprognostic (6.38e-3)" "unprognostic (2.98e-1)" "unprognostic (2.22e-1)" "unprognostic (2.35e-2)" 6.2 3.6 1.7 4.0 2.0 6.2 6.9 1.9 2.0 5.4 1.9 5.7 4.1 7.1 2.9 4.3 3.5 5.6 4.5 1.5 2.7 6.7 27.4 5.3 3.1 2.5 1.9 4.0 1.8 5.4 2.1 15.6 2.6 5.5 4.4 4.5 3.1 7.6 67.6 9.2 8.1 8.0 2.0 4.9 3.4 1.8 2.2 5.6 7.1 58.1 3.0 5.6 4.4 2.6 21.5 32.8 9.0 8.8 11.5 18.5 14.1 40.0 62.9 29.1 28.5 14.5 6.3 4.8 10.4 15.4 70.2 34.6 9.7 26.3 48.2 11.1 5.6 26.1 7.2 7.9 59.0 10.6 2.3 30.8 64.7 35.2 58.9 14.2 24.3 14.9 11.5 0.0 86.4 10.7 15.2 0.1 2.2 10.9 5.1 10.5 67.5 3.1 11.9 42.3 0.7 5.1 17.4 12.5 15.7 15.8 15.2 8.8 84.5 63.9 20.6 13.5 66.0 3.4 8.1 12.3 42.0 24.6 15.7 0.0 0.1 0.0 0.1 0.4 0.3 0.0 0.2 0.1 0.0 0.0 0.2 0.2 0.2 0.1 0.2 0.2 0.1 0.1 1.7 2.0 1.9 2.0 1.5 2.7 2.5 1.9 2.6 2.0 2.2 2.6 35.9 93.0 116.7 28.4 1.6 12.1 3.4 5.5 8.6 0.7 4.6 8.0 5.7 7.2 44.8 0.0 22.9 23.2 2.0 5.2 1.9 3.3 1.7 1.7 13.3 31.1 0.0 17.5 4.2 5.8 7.5 18.5 5.1 1.6 73.2 4.2 17.5 20.5 4.7 0.0 11.9 4.0 2.0 2.2 2.3 1.6 5.6 8.8 1.8 30.0 1.1 8.6 6.2 69.9 28.7 2.9 0.8 7.2 1.9 4.5 25.8 13.4 75.5 6.7 0.0 11.5 17.7 5.3 7.2 7.1 10.4 13.8 9.4 4.8 5.6 1.9 NEK4 "NRK2, pp12301, STK2" ENSG00000114904 "NIMA related kinase 4" P51957 3 52708444-52770946 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 46.0" "Cell type enhanced" "Detected in all" "Spermatocytes: 75.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015750, HPA058543" Enhanced Supported Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA015750: AB_1854367, HPA058543: AB_2732623" "unprognostic (1.32e-1)" "unprognostic (1.57e-1)" "prognostic favorable (2.69e-5)" "unprognostic (9.65e-3)" "unprognostic (3.42e-1)" "unprognostic (6.64e-2)" "unprognostic (8.75e-3)" "unprognostic (2.27e-1)" "unprognostic (7.85e-2)" "unprognostic (5.52e-2)" "unprognostic (1.46e-1)" "unprognostic (1.32e-1)" "unprognostic (3.74e-3)" "unprognostic (5.11e-2)" "unprognostic (2.85e-1)" "unprognostic (1.51e-2)" "unprognostic (8.39e-2)" 6.3 8.2 6.1 7.4 6.7 7.0 9.4 9.1 7.4 8.5 8.6 7.3 6.5 8.7 8.9 6.7 13.6 6.2 6.1 5.9 7.8 9.7 10.8 6.7 8.3 6.8 8.9 13.3 8.1 11.5 7.3 7.6 6.3 7.7 8.2 16.9 7.3 9.0 8.0 3.5 5.6 8.1 6.9 7.2 9.6 46.0 7.8 9.5 13.5 6.1 9.4 7.9 4.9 5.9 19.9 15.2 20.5 16.2 18.2 13.1 22.1 13.9 18.6 25.3 25.4 13.5 14.4 20.4 6.4 13.6 27.9 9.2 25.2 16.3 33.8 20.4 10.6 16.0 18.4 17.3 11.4 39.4 15.4 8.1 14.8 32.5 21.5 13.5 9.6 17.4 20.2 16.1 16.1 17.1 21.4 14.4 17.7 20.9 14.9 18.5 17.8 15.1 14.3 28.3 15.0 9.0 29.1 17.7 14.1 15.7 16.5 23.4 8.9 16.9 17.1 27.3 26.0 17.8 27.9 19.7 19.3 18.2 18.7 13.6 9.8 5.0 3.5 6.1 3.7 2.8 3.0 3.6 5.2 3.5 3.6 3.1 1.4 4.0 4.2 2.6 2.6 5.2 6.1 6.7 9.1 7.4 5.9 7.8 6.8 8.9 6.3 6.9 7.8 5.9 6.2 12.8 8.2 19.2 11.8 4.1 5.3 3.4 4.6 14.1 10.6 6.2 4.6 2.8 11.6 5.5 12.5 7.0 4.8 6.5 9.8 7.0 20.7 24.0 10.6 7.3 4.8 13.3 30.5 9.6 8.1 7.8 12.8 9.9 7.6 14.0 6.8 14.5 8.2 6.7 29.4 9.3 6.1 16.8 4.6 19.5 14.6 10.4 1.8 7.5 14.0 19.4 10.3 16.6 19.3 8.5 2.9 12.4 10.6 5.3 5.4 17.1 22.4 18.9 6.6 12.6 7.3 75.9 27.9 6.9 4.1 6.7 5.8 11.8 9.1 5.2 NFKBIA "IkappaBalpha, IKBA, MAD-3, NFKBI" ENSG00000100906 "NFKB inhibitor alpha" P25963 14 35401513-35404749 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1114.7" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 4056.6;Langerhans cells: 4828.7;Suprabasal keratinocytes: 3420.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 391.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003815, HPA029207" Approved Enhanced Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 15: RT4 - Unknown function" "Cluster 41: Macrophages - Immune response" Cytosol "CAB003815: AB_344886, HPA029207: AB_10603122" "prognostic favorable (1.33e-5)" "unprognostic (3.39e-1)" "unprognostic (7.29e-2)" "unprognostic (7.24e-2)" "unprognostic (8.88e-2)" "unprognostic (1.62e-1)" "unprognostic (3.51e-1)" "unprognostic (2.46e-1)" "unprognostic (2.39e-1)" "unprognostic (2.46e-1)" "unprognostic (2.46e-1)" "unprognostic (7.19e-2)" "unprognostic (2.32e-2)" "unprognostic (3.69e-1)" "unprognostic (4.44e-2)" "unprognostic (9.74e-2)" "unprognostic (3.80e-2)" 281.0 171.3 75.6 150.7 78.0 1114.7 171.4 75.4 92.5 123.8 78.3 121.0 61.2 95.5 29.6 151.8 141.2 130.4 145.5 71.4 75.9 104.5 208.1 366.0 122.6 90.1 76.2 255.7 101.9 68.8 92.4 92.7 81.6 112.6 80.9 18.7 118.3 110.0 139.7 260.5 148.5 92.7 77.0 226.2 130.7 31.7 84.9 123.2 111.9 138.3 181.4 366.2 166.8 79.8 62.5 54.1 20.1 18.2 114.7 75.9 71.1 25.2 240.7 53.3 47.3 16.9 36.5 37.5 66.1 40.2 125.2 79.5 38.3 104.9 76.1 229.2 14.9 18.6 39.9 101.4 68.6 29.9 15.0 83.1 103.5 36.4 92.2 35.5 48.6 18.4 15.9 58.4 38.6 73.0 39.2 71.0 18.6 60.0 33.1 87.8 23.1 31.6 92.8 391.7 17.9 31.2 67.2 115.9 29.7 41.0 66.1 62.2 91.7 72.8 26.5 21.3 41.0 70.9 77.7 64.5 60.8 22.0 15.3 322.0 444.9 301.4 175.3 267.2 264.0 258.4 207.1 182.5 428.9 329.7 178.1 153.0 942.9 285.9 183.7 233.0 154.9 506.4 75.6 78.0 75.4 92.5 71.4 75.9 90.1 76.2 81.6 77.0 84.9 79.8 802.9 535.2 914.0 14.4 505.6 4056.6 1862.8 2061.4 1729.6 27.0 430.7 414.0 188.6 367.4 719.2 62.5 12.5 196.4 762.2 447.8 195.6 875.0 4.3 703.8 935.6 1079.8 203.5 87.8 7.1 394.8 174.9 1145.1 333.8 1440.1 906.1 68.2 313.4 147.2 791.2 48.8 5.1 453.0 634.7 491.4 4828.7 14.7 153.1 1609.0 1085.1 39.4 428.1 95.2 97.9 6.6 8.6 383.5 511.5 116.2 1039.4 1412.0 1051.6 115.9 298.2 37.4 203.8 956.9 847.2 3.3 26.4 1544.6 3420.6 660.0 838.4 91.8 346.0 1004.6 NIM1K "MGC42105, NIM1" ENSG00000177453 "NIM1 serine/threonine protein kinase" Q8IY84 5 43192071-43280850 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 13.7;choroid plexus: 7.9;pituitary gland: 6.5;retina: 10.3" "Cell type enhanced" "Detected in some" "Astrocytes: 29.7;Excitatory neurons: 56.0;Horizontal cells: 18.5;Inhibitory neurons: 44.2;Oligodendrocyte precursor cells: 43.7;Oligodendrocytes: 20.3" "Cancer enriched" "Detected in some" 11 "glioma: 6.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+ RasG12V: 2.0;HDLM-2: 2.3;PC-3: 2.5;U-87 MG: 2.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007695 Approved Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 77: Retina - Visual perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA007695: AB_2667897" "unprognostic (7.97e-2)" "unprognostic (9.79e-2)" "unprognostic (8.74e-2)" "unprognostic (2.10e-1)" "unprognostic (1.67e-1)" "unprognostic (2.17e-1)" "unprognostic (2.40e-1)" "unprognostic (4.35e-2)" "unprognostic (1.35e-1)" "unprognostic (4.28e-2)" "unprognostic (8.84e-4)" "unprognostic (1.25e-1)" "unprognostic (1.55e-5)" "unprognostic (2.18e-1)" "unprognostic (2.66e-1)" "unprognostic (6.46e-3)" "unprognostic (4.98e-3)" 0.4 1.2 11.9 0.4 12.5 0.0 0.4 8.9 13.7 0.9 7.9 1.6 0.1 0.2 0.3 0.4 0.5 0.3 0.8 12.5 11.6 0.3 0.3 1.3 0.2 9.9 10.8 0.2 0.3 1.2 6.5 0.4 9.5 0.8 0.4 10.3 0.8 0.6 0.8 0.6 0.5 0.2 10.4 0.2 1.2 0.4 11.3 0.2 0.9 0.6 0.1 0.6 0.8 11.7 0.1 0.2 0.0 0.0 0.4 0.2 0.0 0.4 1.5 0.5 2.0 0.0 0.0 0.2 0.2 0.4 0.7 0.1 0.3 0.0 1.2 2.3 0.1 0.0 0.3 0.0 0.7 0.1 0.3 0.8 0.0 0.2 0.0 0.7 0.0 0.0 0.1 0.1 0.4 0.1 0.1 0.1 0.0 0.0 2.5 0.1 0.1 0.2 0.0 0.3 0.4 0.0 0.8 0.2 0.1 0.1 0.2 0.7 0.0 0.4 0.3 0.3 0.3 0.7 0.2 0.1 2.7 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 11.9 12.5 8.9 13.7 12.5 11.6 9.9 10.8 9.5 10.4 11.3 11.7 0.4 0.0 4.4 29.7 0.0 0.5 0.1 0.4 1.8 7.6 0.1 0.0 0.3 0.0 0.1 0.0 6.2 0.1 0.1 0.0 0.0 0.0 1.3 0.0 1.0 0.2 0.0 0.0 56.0 0.0 1.4 1.0 0.5 0.3 0.0 0.1 0.0 0.1 0.1 18.5 44.2 0.0 0.0 0.3 0.0 1.8 0.0 0.2 0.0 1.0 0.6 9.9 0.0 43.7 20.3 0.1 0.0 0.7 0.0 0.1 0.0 0.0 0.0 6.6 0.0 1.2 0.6 0.4 0.4 0.2 0.4 0.0 0.4 0.4 0.0 0.1 NKAIN2 "FAM77B, TCBA1" ENSG00000188580 "Sodium/potassium transporting ATPase interacting 2" Q5VXU1 6 123803865-124825640 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "brain: 56.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1721.6;Inhibitory neurons: 636.4;Oligodendrocytes: 2869.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "basophil: 1.8" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.8" "Cell line enhanced" "Detected in some" "BEWO: 2.1;Daudi: 3.0;HEL: 6.4;Karpas-707: 10.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045860 Approved Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA045860: AB_10983192" "unprognostic (3.09e-2)" "unprognostic (1.06e-2)" "unprognostic (2.33e-2)" "unprognostic (4.53e-3)" "unprognostic (5.67e-2)" "unprognostic (1.01e-1)" "unprognostic (1.32e-2)" "unprognostic (2.25e-1)" "unprognostic (2.19e-1)" "unprognostic (5.41e-3)" "unprognostic (2.02e-3)" "unprognostic (2.61e-1)" "unprognostic (5.95e-3)" "unprognostic (3.63e-3)" "unprognostic (1.77e-1)" "unprognostic (1.66e-1)" "unprognostic (1.63e-1)" 0.9 0.4 24.2 0.1 33.6 0.7 0.3 30.1 39.3 0.3 9.8 1.0 0.0 0.1 0.3 0.2 0.3 0.2 1.1 29.2 25.3 0.1 0.2 0.2 0.2 40.7 28.0 0.1 0.1 0.0 1.8 0.1 37.4 0.2 0.1 6.6 0.3 0.2 2.9 0.1 0.3 0.3 34.8 0.1 0.2 0.4 28.8 0.5 0.1 3.4 0.2 0.5 0.3 56.8 0.0 0.0 1.6 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 6.4 0.0 0.0 0.4 0.0 0.0 1.2 0.1 0.0 0.3 0.1 0.0 0.0 0.0 10.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.2 33.6 30.1 39.3 29.2 25.3 40.7 28.0 37.4 34.8 28.8 56.8 0.5 0.0 0.0 97.3 0.0 0.1 0.0 0.2 0.0 3.0 0.0 0.1 1.3 0.0 0.1 0.0 2.1 0.2 0.0 0.0 0.0 0.1 1.7 0.2 0.1 0.3 1.8 2.1 1721.6 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.1 47.1 636.4 0.1 0.0 0.0 0.0 0.0 0.3 1.0 0.0 47.8 0.0 15.8 0.0 19.1 2869.5 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.2 1.1 0.0 0.8 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 NKAPD1 "C11orf57, FLJ10726" ENSG00000150776 "NKAP domain containing 1" Q6ZUT1 11 112074086-112085150 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 32.1;Endometrial stromal cells: 35.4;Proximal tubular cells: 32.9;Theca cells: 35.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039493, HPA039892" Approved Approved Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA039493: AB_10795036, HPA039892: AB_10795372" "unprognostic (5.93e-2)" "unprognostic (3.24e-1)" "unprognostic (6.45e-3)" "unprognostic (1.80e-1)" "unprognostic (1.45e-2)" "unprognostic (5.20e-2)" "prognostic unfavorable (2.70e-4)" "unprognostic (1.17e-1)" "unprognostic (1.45e-2)" "unprognostic (8.61e-2)" "unprognostic (4.67e-3)" "unprognostic (3.17e-2)" "unprognostic (7.05e-3)" "unprognostic (1.15e-2)" "unprognostic (2.86e-1)" "unprognostic (8.24e-2)" "unprognostic (1.41e-1)" 14.2 11.4 9.5 11.6 10.2 13.0 16.7 12.9 11.8 12.1 8.4 12.2 11.3 15.3 11.8 13.9 13.7 11.8 13.0 9.4 10.4 14.6 11.8 11.0 14.2 9.6 9.7 20.1 12.3 14.1 7.7 15.8 10.5 10.7 11.6 33.4 13.7 11.2 18.6 12.1 11.0 12.5 9.6 12.6 11.5 13.6 9.7 16.9 16.0 10.1 14.0 11.5 9.6 11.4 19.5 12.8 26.6 42.9 26.8 31.0 19.5 28.0 23.8 23.1 26.4 39.8 34.2 54.1 41.8 25.3 26.1 27.4 32.1 30.1 30.0 39.0 22.3 41.6 12.7 19.2 24.8 63.3 26.3 31.8 40.5 27.8 63.7 35.1 20.9 44.0 62.4 32.5 23.4 11.8 57.0 39.2 26.5 32.7 28.3 43.5 32.7 44.6 26.6 17.3 22.1 40.4 29.0 35.3 26.1 23.3 44.2 25.9 21.4 30.7 34.4 19.1 24.5 24.5 58.4 111.4 13.0 58.6 31.7 9.1 7.3 4.8 9.8 7.8 10.2 8.4 10.4 6.8 8.1 9.1 10.9 9.5 4.2 13.4 8.9 20.6 9.0 4.8 9.5 10.2 12.9 11.8 9.4 10.4 9.6 9.7 10.5 9.6 9.7 11.4 19.9 32.1 20.7 0.0 9.4 0.0 0.0 0.0 0.0 0.0 24.5 21.0 0.0 0.0 17.3 16.5 0.0 19.6 15.1 0.0 13.7 20.2 0.0 26.0 35.4 8.7 0.0 0.0 0.0 21.4 17.8 11.3 0.0 20.9 8.8 21.8 0.0 0.0 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 13.9 0.0 0.0 0.0 0.0 20.0 0.0 0.0 5.0 0.0 0.0 32.9 17.5 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.0 20.0 6.0 35.6 0.0 0.0 NLRP11 "CLR19.6, NALP11, NOD17, PAN10, PYPAF6" ENSG00000179873 "NLR family pyrin domain containing 11" P59045 19 55785397-55836800 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 1.1;liver: 1.0" "Group enriched" "Detected in some" 5 "Early spermatids: 13.0;Late spermatids: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 115.6;RPMI-8226: 66.1;U-266/70: 110.2;U-266/84: 51.2;U-698: 83.9" "Not detected" "Not detected" "HPA046402, HPA078027" Uncertain Supported Cytosol NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Cytosol "HPA046402: AB_10962951, HPA078027: AB_2732369" "unprognostic (2.36e-2)" "unprognostic (3.59e-1)" "unprognostic (1.09e-1)" "unprognostic (4.36e-3)" "unprognostic (3.31e-2)" "unprognostic (7.88e-2)" "unprognostic (9.95e-3)" "unprognostic (8.04e-2)" "unprognostic (1.94e-1)" "unprognostic (2.52e-1)" "unprognostic (3.75e-2)" "unprognostic (3.14e-2)" "unprognostic (1.10e-2)" "unprognostic (2.06e-1)" "unprognostic (2.89e-2)" "unprognostic (1.76e-2)" "unprognostic (7.61e-2)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.0 0.0 0.2 0.0 0.0 0.3 0.1 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.8 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 115.6 0.0 0.0 1.4 0.0 0.5 0.0 0.0 0.0 3.2 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 24.0 0.0 0.0 0.4 0.7 0.1 0.0 0.4 0.0 2.0 66.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.6 0.1 1.8 1.9 0.1 0.1 110.2 51.2 83.9 2.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.3 0.3 5.1 0.3 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.8 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 NLRP14 "CLR11.2, GC-LRR, Nalp-iota, NALP14, NOD5, PAN8" ENSG00000158077 "NLR family pyrin domain containing 14" Q86W24 11 7020479-7071526 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Astrocytes: 2.3;Bipolar cells: 2.2;Cone photoreceptor cells: 2.1;Distal tubular cells: 1.9;Early spermatids: 2.2;Excitatory neurons: 2.2;Rod photoreceptor cells: 3.2;Spermatocytes: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA039477 Approved Uncertain Cytosol NA NA "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol "HPA039477: AB_10794748" "unprognostic (6.46e-3)" "unprognostic (5.76e-3)" "unprognostic (1.44e-4)" "unprognostic (7.20e-4)" "unprognostic (5.57e-2)" "unprognostic (8.02e-3)" "unprognostic (6.57e-2)" "unprognostic (2.65e-1)" "unprognostic (2.68e-1)" "unprognostic (1.44e-1)" "unprognostic (2.68e-1)" "unprognostic (2.65e-2)" "unprognostic (3.17e-3)" "unprognostic (6.69e-2)" "unprognostic (3.22e-1)" "unprognostic (3.85e-2)" "unprognostic (1.25e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.5 0.1 0.1 0.2 0.2 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.2 0.1 0.2 0.0 0.4 0.0 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.9 0.1 2.2 0.3 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.5 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.2 0.0 0.0 0.0 2.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NME1-NME2 "NM23-LV, NMELV" ENSG00000011052 "NME1-NME2 readthrough" 17 51153590-51171744 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 51.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 43.5;Basal keratinocytes: 38.4;Basal respiratory cells: 23.3;Club cells: 31.1;granulocytes: 22.7;Langerhans cells: 35.0;Melanocytes: 23.2;Suprabasal keratinocytes: 51.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002169, HPA008467, HPA041113, CAB076057" Approved Approved Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 77: Retina - Visual perception" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Cytosol "CAB002169: AB_563917, CAB076057: , HPA008467: AB_1079492, HPA041113: AB_2677305" "unprognostic (2.39e-1)" "unprognostic (5.29e-2)" "unprognostic (9.70e-2)" "unprognostic (5.13e-2)" "prognostic favorable (6.66e-4)" "unprognostic (2.46e-2)" "unprognostic (4.82e-3)" "unprognostic (8.39e-2)" "unprognostic (2.30e-2)" "unprognostic (1.53e-1)" "unprognostic (4.58e-6)" "unprognostic (1.03e-1)" "unprognostic (2.74e-6)" "unprognostic (1.84e-1)" "unprognostic (9.72e-2)" "unprognostic (1.50e-1)" "unprognostic (1.43e-3)" 12.3 21.0 7.2 15.1 7.4 10.9 8.7 6.5 10.3 8.7 6.3 6.7 3.6 9.3 0.8 14.7 9.4 2.2 9.9 8.7 6.8 12.4 16.4 9.2 8.7 7.8 6.7 5.6 16.6 6.4 11.9 7.1 7.8 6.8 2.9 51.2 13.8 2.2 12.9 12.2 4.9 6.8 6.5 7.9 9.0 3.0 7.7 6.2 7.4 3.6 3.7 13.1 9.9 7.3 22.4 5.5 21.2 48.3 27.9 13.1 7.7 32.3 20.8 15.9 9.5 11.1 8.6 30.1 34.3 41.3 33.2 21.9 25.1 44.7 8.8 51.0 46.6 15.2 9.1 22.7 30.5 25.5 42.2 25.4 36.2 21.2 31.4 49.6 28.0 38.8 21.2 36.7 12.3 14.6 141.2 37.4 19.6 66.5 9.5 49.5 21.0 85.0 23.0 9.4 70.1 56.4 13.9 112.7 38.3 37.8 87.8 86.3 34.1 57.0 14.6 76.8 26.2 60.8 52.2 41.4 26.7 24.6 46.4 0.4 16.0 0.7 18.2 24.1 26.9 14.1 15.7 17.1 45.9 23.4 13.9 16.9 1.7 14.4 11.9 28.4 16.9 20.8 7.2 7.4 6.5 10.3 8.7 6.8 7.8 6.7 7.8 6.5 7.7 7.3 0.0 16.0 43.5 0.0 1.5 38.4 0.0 23.3 2.2 0.0 0.0 0.0 2.2 0.0 31.1 0.0 0.0 0.0 0.1 8.0 0.0 0.0 0.0 0.2 0.2 5.1 1.8 0.4 3.9 0.0 0.1 12.1 1.5 0.2 22.7 0.1 0.4 0.6 0.0 0.0 3.5 7.2 10.2 0.0 35.0 0.0 0.3 6.8 23.2 0.0 0.0 0.0 0.0 2.0 0.9 0.0 1.1 0.0 2.0 0.0 0.0 0.1 16.3 0.0 0.0 0.0 16.4 0.1 0.0 3.8 51.9 0.0 3.0 0.0 7.8 0.1 NMNAT2 "C1orf15, KIAA0479, PNAT2" ENSG00000157064 "Nicotinamide nucleotide adenylyltransferase 2" Q9BZQ4 1 183248237-183418380 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.5;heart muscle: 18.3;pituitary gland: 18.4" "Cell type enhanced" "Detected in many" "Early spermatids: 54.3;Excitatory neurons: 195.5;Inhibitory neurons: 265.4;Oligodendrocyte precursor cells: 98.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 26.2;SCLC-21H: 80.6;SuSa: 25.1;U-2197: 45.8;U-87 MG: 35.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015708, HPA061714" Enhanced Approved Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA015708: , HPA061714: AB_2732669" "unprognostic (3.70e-1)" "unprognostic (7.98e-3)" "unprognostic (8.83e-2)" "unprognostic (4.16e-2)" "unprognostic (8.95e-2)" "unprognostic (9.96e-2)" "unprognostic (1.81e-1)" "unprognostic (1.35e-1)" "unprognostic (7.92e-2)" "unprognostic (8.09e-2)" "unprognostic (1.33e-2)" "unprognostic (3.20e-1)" "unprognostic (2.73e-3)" "unprognostic (2.90e-3)" "unprognostic (1.87e-1)" "unprognostic (7.51e-2)" "unprognostic (1.02e-1)" 8.5 5.9 13.1 0.8 14.8 0.0 5.1 17.2 45.5 2.1 0.0 2.3 0.4 1.2 1.4 0.8 2.3 2.8 18.3 15.6 21.4 0.4 0.0 0.7 0.6 0.7 0.8 0.4 1.7 0.2 18.4 0.9 6.7 0.2 0.9 6.5 0.5 2.5 0.5 0.9 0.9 1.5 0.0 0.1 1.1 8.9 0.8 0.5 6.0 1.4 0.6 0.7 0.8 10.0 1.4 0.5 5.5 0.0 3.1 12.5 4.6 3.4 8.9 1.8 0.6 2.7 5.4 0.0 14.2 0.8 1.5 2.2 0.2 0.1 3.3 0.0 0.1 0.0 2.2 0.0 0.5 0.0 0.1 26.2 1.1 2.1 0.5 11.1 0.5 0.0 0.0 0.1 2.1 0.1 0.0 0.5 9.7 0.1 5.4 0.0 0.2 0.0 5.9 4.5 80.6 6.2 0.7 0.3 0.0 25.1 0.7 1.5 3.0 2.5 0.9 45.8 3.3 0.6 0.0 0.0 35.3 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 14.8 17.2 45.5 15.6 21.4 0.7 0.8 6.7 0.0 0.8 10.0 21.4 0.0 1.5 3.9 0.0 0.8 0.2 0.6 0.6 12.1 0.2 0.1 35.2 0.0 2.0 0.0 0.0 0.7 0.1 0.1 0.0 0.2 54.3 2.7 0.3 5.2 0.0 0.0 195.5 0.0 12.9 5.7 0.0 7.4 0.0 0.2 0.0 0.0 0.7 20.2 265.4 0.0 4.1 1.0 0.0 42.3 0.0 0.5 1.8 11.2 0.0 0.3 0.0 98.5 6.1 0.6 0.0 0.0 0.0 0.1 0.0 0.0 3.4 2.9 19.7 0.3 12.0 0.4 0.2 0.1 0.3 1.4 0.2 0.0 0.0 0.0 NPEPPS "MP100, PSA" ENSG00000141279 "Aminopeptidase puromycin sensitive" P55786 17 47522942-47624665 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021453, HPA045649" Uncertain Supported Cytosol No No 3000000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 59: Non-specific - Translation" "Cluster 6: T47d - Mammary gland" "Cluster 44: Endometrium - Transcription" Cytosol "HPA021453: AB_2670709, HPA045649: AB_2679406" "unprognostic (1.63e-1)" "unprognostic (3.15e-2)" "prognostic favorable (3.39e-5)" "unprognostic (2.66e-2)" "unprognostic (1.53e-1)" "unprognostic (5.92e-2)" "prognostic unfavorable (3.67e-5)" "unprognostic (3.84e-2)" "unprognostic (1.22e-1)" "unprognostic (1.77e-1)" "unprognostic (3.85e-2)" "unprognostic (3.63e-2)" "unprognostic (1.93e-1)" "unprognostic (8.55e-2)" "unprognostic (1.52e-1)" "unprognostic (1.23e-2)" "unprognostic (1.07e-1)" 32.2 50.0 30.6 19.4 34.8 7.3 30.1 30.7 41.1 41.5 26.1 38.6 20.3 32.0 11.1 92.2 32.6 22.2 30.6 32.9 30.3 30.9 23.8 30.5 18.4 35.7 34.2 39.9 34.2 30.1 26.7 27.3 35.7 27.9 27.4 21.0 44.4 20.6 114.5 47.3 37.1 33.7 26.1 31.9 33.4 19.2 34.2 26.4 26.8 86.6 27.5 34.8 58.2 30.5 105.7 81.7 67.3 49.4 92.1 81.9 147.5 47.5 63.9 70.4 66.5 55.7 100.6 68.4 76.1 69.2 70.1 62.0 83.7 44.8 108.7 31.5 73.2 76.5 62.3 59.2 48.3 48.8 46.6 61.5 41.1 52.7 26.8 99.2 77.5 20.1 72.5 30.7 109.9 37.2 66.0 34.7 47.8 74.4 68.0 50.5 107.2 60.1 82.6 81.0 59.7 46.0 59.1 34.9 44.7 122.0 256.3 35.5 88.6 44.1 35.2 72.5 34.9 63.7 81.1 39.9 64.8 25.3 33.5 14.2 9.9 12.4 8.8 7.9 9.6 7.7 7.2 9.2 9.7 6.9 6.3 7.8 28.4 8.8 9.1 10.1 8.8 6.3 30.6 34.8 30.7 41.1 32.9 30.3 35.7 34.2 35.7 26.1 34.2 30.5 32.0 83.3 59.1 68.6 44.7 77.9 68.9 40.2 109.8 144.6 76.6 33.8 60.3 55.8 53.6 42.3 268.9 81.2 35.6 87.0 27.4 69.3 34.2 95.2 80.9 45.4 44.3 44.6 98.0 54.4 74.4 66.0 58.1 158.1 41.7 62.7 45.7 32.5 40.5 112.7 95.3 44.1 38.7 51.0 62.1 50.8 52.8 45.4 58.7 37.5 51.5 38.7 38.1 69.4 74.9 103.4 61.6 50.0 52.5 106.2 58.7 46.5 63.8 153.3 78.9 53.8 53.5 52.0 28.6 101.6 102.6 104.7 40.4 45.9 51.5 195.2 NPR3 "ANPRC, C5orf23, FLJ14054, GUCY2B, NPRC" ENSG00000113389 "Natriuretic peptide receptor 3" P17342 5 32689070-32791724 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 107.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 52.8;Granulosa cells: 97.9;Proximal tubular cells: 143.4" "Cancer enhanced" "Detected in many" "renal cancer: 19.4" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "neutrophil: 3.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.3" "Cell line enhanced" "Detected in some" "ASC TERT1: 35.3;fHDF/TERT166: 22.8;HeLa: 81.4;HSkMC: 50.0;U-138 MG: 21.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052702 Supported Approved Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 20: HeLa - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA052702: AB_2681922" "unprognostic (8.56e-3)" "unprognostic (1.54e-2)" "unprognostic (1.23e-2)" "unprognostic (1.10e-1)" "unprognostic (7.64e-3)" "unprognostic (2.66e-3)" "unprognostic (1.68e-2)" "unprognostic (9.28e-2)" "unprognostic (6.78e-3)" "unprognostic (1.76e-1)" "unprognostic (6.07e-2)" "unprognostic (3.46e-3)" "prognostic favorable (5.43e-6)" "unprognostic (6.00e-4)" "unprognostic (5.74e-2)" "unprognostic (2.80e-2)" "unprognostic (3.38e-2)" 21.3 3.4 1.4 0.8 1.2 4.5 3.8 0.9 1.7 8.0 5.6 5.3 0.7 4.1 2.0 5.3 4.7 4.3 27.3 1.3 2.0 107.8 4.8 11.1 0.9 1.5 1.4 1.7 1.3 1.3 0.6 9.5 1.3 6.3 1.1 2.6 1.1 8.9 5.8 5.0 1.4 3.0 1.1 9.6 1.0 1.7 1.3 4.9 13.0 9.5 2.0 1.8 4.5 2.0 0.3 4.3 0.2 0.4 2.4 35.3 0.1 10.0 1.9 0.6 0.6 0.0 0.2 0.0 0.2 22.8 0.7 0.0 4.9 0.1 1.2 0.1 0.0 0.4 81.4 0.0 7.1 0.1 0.2 50.0 0.6 2.6 6.9 2.3 0.3 0.1 0.1 0.6 3.3 0.6 0.0 0.5 0.1 0.0 11.9 0.1 0.0 0.0 0.0 0.2 0.2 0.0 3.5 13.3 0.1 0.3 0.2 0.0 0.3 21.5 0.3 1.8 0.3 0.2 0.1 0.0 3.5 0.1 0.3 0.1 0.3 0.2 0.3 0.1 0.2 0.4 0.3 0.2 0.0 0.5 0.4 0.5 3.3 0.4 0.0 0.4 0.1 0.1 1.4 1.2 0.9 1.7 1.3 2.0 1.5 1.4 1.3 1.1 1.3 2.0 3.9 16.0 4.9 1.0 0.8 5.4 0.1 1.6 24.5 11.6 0.2 1.1 27.3 0.0 1.7 9.2 0.0 0.0 0.2 0.1 52.8 0.1 1.4 4.5 8.5 11.9 0.0 13.9 0.4 0.0 0.1 2.6 0.0 16.5 3.8 97.9 15.7 1.6 0.1 3.3 11.4 0.0 0.0 0.3 0.0 3.2 11.1 1.3 0.0 0.0 0.2 1.7 0.0 1.0 0.3 0.0 0.1 12.8 1.4 1.9 0.0 143.4 3.7 1.5 6.6 0.3 6.6 0.1 1.2 23.0 1.3 0.1 1.3 16.5 0.0 0.3 NPRL3 "C16orf35, CGTHBA, HS-40, MARE, NPR3, RMD11" ENSG00000103148 "NPR3 like, GATOR1 complex subunit" Q12980 16 84271-138677 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 134.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011741 Uncertain Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" Cytosol "HPA011741: AB_1845577" "unprognostic (1.34e-1)" "unprognostic (1.32e-1)" "unprognostic (3.13e-2)" "unprognostic (1.13e-1)" "unprognostic (1.24e-2)" "unprognostic (4.87e-2)" "unprognostic (6.18e-3)" "unprognostic (9.50e-2)" "unprognostic (7.28e-2)" "unprognostic (4.85e-2)" "unprognostic (9.07e-3)" "unprognostic (1.68e-1)" "unprognostic (3.15e-2)" "unprognostic (8.69e-2)" "unprognostic (1.65e-1)" "unprognostic (3.11e-1)" "unprognostic (2.73e-1)" 9.6 10.4 17.5 7.2 18.2 19.1 8.5 16.7 22.2 10.1 15.7 6.5 7.3 10.5 5.2 9.3 12.1 6.3 8.9 17.7 18.0 8.0 10.0 7.8 9.4 17.1 18.1 12.9 10.9 12.7 11.7 6.6 16.9 8.8 4.8 7.1 11.0 7.1 15.5 9.9 5.6 7.2 15.5 8.3 6.8 9.4 18.2 7.0 11.0 10.3 6.6 6.5 8.2 18.2 14.5 29.0 12.6 32.2 33.7 16.9 19.8 17.2 16.8 21.3 16.6 46.6 25.6 26.5 22.5 25.5 13.8 17.0 20.5 29.7 12.3 29.2 16.0 38.8 17.3 34.2 31.1 15.9 25.6 20.7 22.2 28.4 24.9 16.0 20.3 21.1 38.6 24.6 19.1 51.2 17.6 12.3 11.9 10.0 20.8 30.1 10.8 37.9 21.6 12.2 26.9 17.1 22.8 30.1 14.3 6.5 22.2 11.1 19.2 32.9 18.2 20.0 13.3 25.9 14.7 37.7 1.1 19.2 18.3 0.0 2.4 0.3 3.0 2.2 3.2 2.0 2.6 2.5 3.5 2.0 2.5 2.9 0.2 2.0 3.1 2.6 2.9 2.2 17.5 18.2 16.7 22.2 17.7 18.0 17.1 18.1 16.9 15.5 18.2 18.2 10.4 12.8 11.7 30.0 22.2 9.4 17.6 15.7 14.8 58.1 16.6 16.8 9.0 12.8 9.2 11.0 66.7 24.6 20.4 6.8 23.5 16.4 31.0 11.8 18.1 13.0 9.6 134.5 29.7 8.9 35.2 17.3 15.8 9.4 3.8 49.2 15.7 10.2 19.7 55.5 30.8 11.7 10.2 14.2 6.4 73.8 22.7 12.8 12.4 15.9 16.4 29.5 79.3 21.1 40.4 11.4 6.6 19.5 14.0 23.3 8.0 23.9 11.0 57.2 6.6 15.6 14.9 62.2 43.0 16.0 5.5 15.3 18.8 28.2 14.4 10.4 NQO1 "DHQU, DIA4, DTD, NMOR1, QR1" ENSG00000181019 "NAD(P)H quinone dehydrogenase 1" P15559 16 69706996-69726668 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 522.7" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 539.8;Respiratory ciliated cells: 471.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 2434.0;OE19: 4177.0;SiHa: 2756.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007308, CAB012421" Enhanced Supported Cytosol NA NA 490000 "Cluster 48: NK-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "CAB012421: , HPA007308: AB_1079501" "unprognostic (1.04e-2)" "unprognostic (1.95e-3)" "unprognostic (3.14e-1)" "unprognostic (3.76e-3)" "unprognostic (9.03e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (1.05e-3)" "unprognostic (1.97e-1)" "unprognostic (5.07e-2)" "unprognostic (1.24e-2)" "unprognostic (1.49e-2)" "unprognostic (2.25e-1)" "unprognostic (2.41e-2)" "unprognostic (6.36e-2)" "unprognostic (1.45e-1)" "unprognostic (1.98e-1)" "unprognostic (3.27e-1)" 100.9 95.1 88.9 20.7 97.2 0.8 264.8 88.1 165.6 24.3 113.4 85.6 106.8 16.1 27.2 162.2 29.3 183.1 24.3 86.7 95.0 93.9 5.6 36.5 4.8 83.5 86.2 8.9 9.2 19.5 15.3 12.0 85.9 20.7 74.0 21.4 47.7 25.1 34.2 11.7 56.1 35.0 83.0 22.8 522.7 6.4 93.6 4.3 112.7 27.0 16.5 79.0 34.2 86.8 224.2 2434.0 203.4 901.3 473.1 682.7 77.5 363.1 632.7 363.9 547.0 302.0 1395.7 7.1 433.1 1850.6 634.3 232.1 79.1 410.3 185.2 91.3 3.3 10.9 564.4 2169.9 631.7 53.8 170.6 166.2 246.8 642.8 74.4 537.9 903.9 18.5 95.3 16.3 1914.1 725.9 11.6 98.7 107.0 4177.0 237.1 18.9 44.0 101.6 708.3 781.5 73.0 17.2 2756.6 384.8 1690.4 226.6 631.3 173.1 626.5 368.8 155.8 140.0 297.1 12.7 53.1 11.2 470.2 29.1 1864.0 1.1 3.9 0.3 6.3 0.4 3.1 5.7 7.3 8.3 3.8 2.4 2.2 5.3 0.9 18.7 0.4 1.3 15.6 5.1 88.9 97.2 88.1 165.6 86.7 95.0 83.5 86.2 85.9 83.0 93.6 86.8 88.5 25.6 14.6 8.8 2.9 5.2 26.4 185.5 32.5 10.0 31.1 30.5 4.8 138.7 90.9 42.3 4.2 1.7 3.5 165.7 146.8 25.6 0.4 117.2 11.7 81.0 20.4 1.3 1.9 147.5 4.3 32.9 539.8 65.7 19.7 10.1 28.5 2.6 15.2 3.3 1.6 81.7 107.8 3.5 7.6 1.2 25.1 10.9 17.8 4.7 128.5 10.6 7.2 0.0 5.0 75.1 59.4 12.0 2.3 22.6 62.9 44.3 471.3 15.1 6.6 21.1 72.1 0.3 1.3 128.3 4.5 1.9 5.6 17.3 51.5 40.6 NRBP1 "BCON3, MADM, MUDPNP, NRBP" ENSG00000115216 "Nuclear receptor binding protein 1" Q9UHY1 2 27427790-27442259 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 234.3;Extravillous trophoblasts: 231.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029527, CAB033078" Supported Supported Cytosol NA NA 39000 "Cluster 2: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "CAB033078: AB_2154375, HPA029527: AB_10601379" "unprognostic (4.95e-3)" "unprognostic (1.29e-1)" "unprognostic (1.09e-1)" "unprognostic (1.38e-1)" "unprognostic (3.62e-2)" "unprognostic (3.95e-1)" "prognostic unfavorable (2.22e-5)" "unprognostic (7.36e-2)" "unprognostic (1.44e-1)" "unprognostic (6.11e-2)" "unprognostic (3.13e-1)" "unprognostic (2.60e-1)" "prognostic unfavorable (5.84e-5)" "unprognostic (1.26e-1)" "unprognostic (2.69e-1)" "unprognostic (2.75e-2)" "unprognostic (3.48e-3)" 59.7 49.6 38.1 49.4 38.9 109.1 55.2 39.3 42.1 76.1 44.3 72.0 52.2 69.7 43.1 99.9 55.1 53.5 57.6 37.7 44.5 44.7 55.2 50.3 54.0 43.1 44.2 63.7 51.0 44.5 46.9 83.0 45.6 51.6 46.5 47.6 57.2 60.7 126.2 70.7 52.4 75.6 36.8 51.2 51.8 71.1 42.1 51.9 42.4 90.3 67.2 67.3 70.8 37.5 123.7 121.0 98.1 130.9 148.2 146.6 119.0 114.8 143.1 159.8 123.5 123.5 49.1 35.5 83.7 182.9 158.6 82.9 98.4 102.9 102.3 70.0 61.4 70.8 47.0 163.5 124.1 40.0 91.1 120.8 127.3 163.7 108.6 103.9 178.5 38.8 40.5 54.8 142.3 185.6 53.0 96.1 124.0 108.5 75.7 40.5 209.5 40.0 113.8 84.1 26.3 74.1 135.6 96.5 72.4 108.8 53.3 43.9 143.0 140.6 138.5 85.1 94.2 114.3 122.7 42.4 109.8 68.6 71.9 203.6 88.6 187.0 96.7 118.0 85.6 59.3 82.3 87.9 90.2 55.1 73.9 77.1 117.9 91.0 111.5 57.4 107.8 117.4 38.1 38.9 39.3 42.1 37.7 44.5 43.1 44.2 45.6 36.8 42.1 37.5 47.3 6.4 21.4 15.7 46.4 57.2 57.8 73.9 56.9 37.8 34.3 31.5 25.9 28.6 47.2 35.0 35.5 155.7 72.6 67.4 31.3 88.7 234.3 47.5 66.8 54.9 28.1 42.7 14.8 95.9 231.5 61.8 30.1 64.1 20.8 39.3 47.2 38.8 77.3 28.6 15.9 42.7 38.7 35.2 44.7 38.6 46.0 46.6 30.2 8.4 67.2 46.8 51.5 13.0 17.0 100.0 45.6 60.5 72.2 49.7 67.4 52.6 36.5 56.3 32.9 37.4 77.6 92.8 106.8 50.3 52.4 203.2 67.2 36.9 30.8 58.8 NRBP2 DKFZp434P086 ENSG00000185189 "Nuclear receptor binding protein 2" Q9NSY0 8 143833583-143840973 "Enzymes, Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 134.2;Oligodendrocytes: 120.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020944, HPA029051, HPA029052" Approved Approved Cytosol NA NA "Cluster 70: Brain - Nervous system development" "Cluster 20: HeLa - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol "CAB020944: , HPA029051: AB_2672886, HPA029052: AB_10602714" "unprognostic (1.84e-1)" "unprognostic (4.66e-2)" "unprognostic (2.54e-2)" "unprognostic (1.53e-3)" "unprognostic (1.01e-1)" "unprognostic (2.00e-2)" "unprognostic (4.03e-1)" "unprognostic (2.86e-1)" "unprognostic (3.97e-1)" "unprognostic (1.08e-1)" "unprognostic (2.24e-1)" "unprognostic (2.47e-2)" "prognostic unfavorable (2.01e-5)" "unprognostic (3.86e-2)" "unprognostic (3.98e-1)" "unprognostic (4.56e-2)" "unprognostic (2.04e-1)" 18.8 9.6 21.4 6.4 35.9 1.6 18.4 35.6 28.7 15.1 12.6 28.2 7.6 17.3 7.4 9.5 17.6 10.3 15.1 24.9 25.8 18.1 32.3 16.6 4.5 49.6 35.7 13.4 10.7 8.9 14.5 5.7 47.1 19.6 5.6 7.4 19.7 12.6 6.9 17.7 11.1 11.7 30.6 7.1 14.0 6.9 36.4 3.9 15.8 7.1 3.4 14.2 14.0 48.5 10.2 12.9 11.4 14.0 16.5 25.6 2.6 18.7 9.0 7.2 10.3 3.1 8.8 1.1 5.3 24.1 5.2 15.5 7.0 6.6 3.2 12.4 4.7 2.0 36.0 5.3 18.1 0.0 4.1 30.3 15.5 3.1 3.5 22.4 10.5 3.4 6.7 12.7 15.2 3.5 0.8 0.4 3.7 10.1 5.5 3.4 10.0 4.5 8.9 3.1 3.9 7.2 25.3 13.3 10.1 5.9 18.7 0.8 22.5 4.6 12.5 20.4 6.8 6.3 0.5 0.3 22.8 4.1 5.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.4 35.9 35.6 28.7 24.9 25.8 49.6 35.7 47.1 30.6 36.4 48.5 15.1 44.8 13.7 134.2 2.0 9.2 6.2 5.2 5.7 15.4 16.3 23.2 9.9 41.5 10.4 11.0 14.6 0.9 3.2 9.2 0.0 4.3 0.5 8.1 15.2 10.4 9.0 0.0 41.8 4.0 1.0 11.2 15.3 14.1 0.0 8.5 7.5 41.7 2.8 16.8 32.7 8.4 16.2 5.7 4.6 1.2 28.9 4.5 10.6 22.5 3.9 17.7 3.1 30.2 120.7 5.4 3.6 21.4 2.3 7.1 3.9 4.4 7.0 11.4 13.1 14.2 18.3 1.2 3.3 4.7 9.1 0.8 4.4 7.2 6.2 5.0 NRIP3 C11orf14 ENSG00000175352 "Nuclear receptor interacting protein 3" Q9NQ35 11 8980576-9004049 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.9;retina: 24.5;testis: 43.5" "Cell type enhanced" "Detected in many" "Early spermatids: 545.3;Horizontal cells: 242.3;Late spermatids: 478.6;Spermatocytes: 189.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 13.1" "Lineage enriched" "Detected in many" 12 "granulocytes: 13.1" "Cell line enhanced" "Detected in many" "HMC-1: 51.4;SiHa: 34.3;U-87 MG: 47.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058827, HPA072961" Approved Approved Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA058827: AB_2683829, HPA072961: " "unprognostic (2.05e-1)" "unprognostic (1.42e-1)" "unprognostic (8.84e-3)" "unprognostic (5.43e-3)" "unprognostic (1.66e-1)" "unprognostic (2.68e-1)" "unprognostic (2.03e-4)" "unprognostic (1.25e-1)" "unprognostic (1.88e-1)" "unprognostic (3.63e-2)" "unprognostic (1.04e-2)" "unprognostic (1.11e-1)" "unprognostic (1.33e-1)" "unprognostic (1.13e-1)" "unprognostic (1.41e-1)" "unprognostic (5.88e-3)" "unprognostic (1.30e-1)" 1.1 10.2 16.7 1.6 13.4 13.8 3.9 23.2 42.1 3.4 0.0 1.5 0.5 3.2 3.1 0.8 2.2 1.6 1.2 72.9 20.8 1.4 0.2 0.8 0.8 20.5 18.4 0.5 0.4 5.4 1.5 0.8 23.6 0.7 0.6 24.5 0.6 0.9 0.3 0.6 0.6 2.3 25.1 0.5 2.5 43.5 31.6 0.9 0.9 0.2 0.6 1.3 0.7 17.2 0.0 0.9 1.9 0.3 0.7 2.7 0.1 20.3 8.0 16.2 16.9 3.1 1.8 0.1 3.0 5.9 9.6 0.2 5.5 0.5 28.0 1.7 8.5 2.2 1.2 0.2 1.4 26.5 51.4 3.7 0.3 16.7 0.1 17.1 13.3 4.4 4.2 0.2 15.0 0.0 1.3 8.6 6.6 0.1 0.0 0.0 2.8 0.0 0.3 1.2 5.4 1.7 34.3 0.9 5.3 1.4 3.5 2.5 16.6 24.7 11.8 1.4 0.1 0.1 0.0 0.0 47.9 3.1 12.3 13.1 0.1 2.0 0.1 0.3 0.2 0.1 0.5 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 1.1 0.3 16.7 13.4 23.2 42.1 72.9 20.8 20.5 18.4 23.6 25.1 31.6 17.2 4.0 0.0 1.3 1.0 1.7 2.2 5.7 0.5 0.0 19.6 12.1 8.9 1.6 0.0 0.4 0.0 10.4 0.4 7.4 0.6 5.9 0.4 545.3 3.7 4.1 2.5 5.3 2.7 11.5 1.1 0.5 2.5 7.1 6.6 15.8 2.4 0.0 0.0 12.1 242.3 96.3 0.5 8.2 3.1 17.2 478.6 6.8 12.8 3.6 0.0 0.6 4.4 0.0 4.5 1.6 8.2 0.1 5.7 1.2 3.5 0.1 0.0 0.1 10.6 0.0 6.0 3.6 189.8 44.0 0.9 1.0 1.0 5.5 5.6 0.2 4.2 NT5C "cdN, DNT-1, DNT1, PN-I, UMPH2" ENSG00000125458 "5', 3'-nucleotidase, cytosolic" Q8TCD5 17 75130225-75131757 "Metabolic proteins, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA021581, HPA023632" Approved Supported Cytosol NA NA 760000 "Cluster 10: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA021581: AB_1854663, HPA023632: AB_1854662" "unprognostic (3.83e-2)" "unprognostic (4.45e-2)" "unprognostic (2.39e-1)" "unprognostic (3.61e-2)" "unprognostic (1.26e-1)" "unprognostic (9.21e-2)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.26e-1)" "unprognostic (7.25e-2)" "unprognostic (8.26e-3)" "unprognostic (7.15e-2)" "unprognostic (2.22e-1)" "unprognostic (6.57e-2)" "unprognostic (1.58e-1)" "unprognostic (1.10e-1)" "unprognostic (2.13e-1)" "prognostic favorable (7.66e-4)" 31.6 31.4 14.5 17.9 15.9 16.3 31.8 16.5 17.4 37.0 14.8 43.0 24.5 34.7 5.2 45.9 32.1 8.4 32.6 14.1 16.7 47.8 29.1 29.2 18.3 17.1 15.5 37.5 33.7 11.7 18.9 10.2 15.6 35.7 13.1 8.7 25.8 15.3 41.1 33.8 43.7 7.6 16.6 40.7 36.8 15.2 15.5 16.0 37.7 16.1 15.2 37.9 35.9 18.4 52.5 77.7 25.3 26.5 7.5 15.4 33.7 29.5 26.2 29.7 18.8 29.5 58.3 35.5 21.5 21.0 5.2 33.7 18.1 37.7 16.5 16.1 51.3 40.5 68.7 50.0 38.0 38.8 17.2 23.1 17.4 21.3 57.0 11.9 33.0 27.6 38.4 16.8 30.2 51.2 28.0 39.0 26.5 43.6 50.6 24.9 32.9 50.9 39.3 26.7 30.0 60.1 28.3 34.8 43.9 14.0 49.8 27.2 20.4 25.0 62.1 9.8 40.3 33.3 5.6 41.1 23.8 23.3 40.4 183.7 29.7 48.9 39.2 49.6 27.7 94.9 25.5 33.6 37.9 87.4 21.6 33.5 14.4 72.6 50.7 50.4 45.2 30.2 14.5 15.9 16.5 17.4 14.1 16.7 17.1 15.5 15.6 16.6 15.5 18.4 23.0 32.1 19.5 22.2 132.9 47.4 86.1 108.8 90.5 66.0 58.8 101.9 16.4 77.2 35.2 58.8 20.9 64.9 85.8 272.8 78.2 102.2 2.1 53.2 53.5 26.6 64.1 59.5 7.7 121.4 100.4 59.8 181.5 43.2 46.3 59.0 11.7 41.9 74.5 42.1 8.0 133.4 52.9 55.7 64.4 6.8 59.4 56.2 58.7 18.7 108.4 55.9 98.9 19.6 19.2 127.5 221.6 47.4 51.2 115.8 231.6 144.2 31.1 65.5 32.9 39.0 107.6 19.0 49.6 89.4 44.3 31.2 67.4 98.4 152.8 85.9 NTPCR "C1orf57, HCR-NTPase, MGC13186, THEP1" ENSG00000135778 "Nucleoside-triphosphatase, cancer-related" Q9BSD7 1 232950605-232983882 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028125, HPA054304" Uncertain Approved Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA028125: AB_10601091, HPA054304: AB_2682443" "unprognostic (2.67e-1)" "unprognostic (2.28e-2)" "unprognostic (1.63e-2)" "unprognostic (7.59e-2)" "unprognostic (5.85e-3)" "unprognostic (1.04e-1)" "unprognostic (8.70e-3)" "unprognostic (2.12e-1)" "unprognostic (6.00e-2)" "unprognostic (5.03e-3)" "unprognostic (4.78e-2)" "unprognostic (1.08e-1)" "unprognostic (2.66e-1)" "unprognostic (2.74e-2)" "unprognostic (1.73e-1)" "unprognostic (1.08e-1)" "unprognostic (6.37e-3)" 3.0 4.0 8.9 2.0 9.3 0.8 3.6 8.3 9.6 5.0 10.9 4.5 2.0 4.2 3.8 3.2 4.7 3.2 4.5 9.0 10.3 3.6 2.8 3.4 2.9 11.4 9.3 5.3 5.9 5.3 4.2 2.5 12.0 4.1 4.3 8.0 3.3 4.0 13.5 4.3 3.9 4.1 9.8 3.4 3.0 2.2 10.0 3.6 4.4 11.8 2.7 3.8 4.2 9.1 2.0 4.9 5.4 2.7 4.0 5.2 0.1 1.3 4.3 4.0 5.5 3.5 2.3 3.1 2.9 2.7 2.2 2.6 3.7 5.0 4.4 2.3 6.9 0.9 3.4 4.5 4.1 1.7 1.8 6.9 9.4 3.9 3.9 4.0 3.3 5.8 2.8 4.6 4.8 1.5 4.4 4.4 5.4 4.0 5.7 2.9 3.5 4.6 5.9 2.4 4.7 7.8 1.9 1.6 1.9 4.0 4.0 3.8 2.5 3.3 2.7 3.6 3.7 5.2 4.6 3.5 3.9 4.1 4.9 0.3 0.5 0.2 0.6 0.6 0.7 0.5 0.9 0.3 0.4 0.6 1.2 1.0 0.9 0.5 0.5 0.1 1.1 0.4 8.9 9.3 8.3 9.6 9.0 10.3 11.4 9.3 12.0 9.8 10.0 9.1 45.5 19.2 21.1 24.8 16.9 19.4 37.3 85.3 24.5 15.8 31.5 34.8 63.9 38.6 36.3 25.8 27.1 68.9 16.1 37.3 93.9 62.2 47.7 27.3 29.4 29.1 25.8 15.8 16.1 64.5 59.1 33.1 16.3 27.7 16.5 44.9 23.9 34.3 42.3 10.1 16.1 50.0 75.3 22.8 17.3 27.3 20.2 21.2 23.2 15.0 30.1 41.0 47.4 16.1 20.8 46.5 31.2 30.5 12.2 40.1 66.0 82.0 27.2 21.8 13.1 21.3 27.7 86.5 40.4 40.1 23.9 28.0 16.5 67.9 66.5 41.6 NUBP1 "CIAO5, NBP1, NBP35" ENSG00000103274 "Nucleotide binding protein 1" P53384 16 10743786-10769351 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041656, HPA041799" Enhanced Supported Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 3: Monocytes - Immune response regulation" Cytosol "HPA041656: AB_10960278, HPA041799: AB_10960692" "unprognostic (2.51e-2)" "prognostic favorable (2.81e-5)" "unprognostic (4.01e-3)" "unprognostic (1.66e-3)" "unprognostic (2.81e-1)" "unprognostic (7.04e-2)" "unprognostic (1.33e-1)" "unprognostic (7.30e-3)" "unprognostic (8.28e-2)" "unprognostic (5.08e-2)" "unprognostic (1.61e-1)" "unprognostic (2.50e-1)" "prognostic favorable (7.61e-8)" "unprognostic (2.12e-1)" "unprognostic (1.04e-1)" "unprognostic (8.23e-2)" "unprognostic (1.69e-2)" 22.7 39.3 12.6 25.9 12.7 31.0 22.0 13.6 16.5 19.9 15.2 27.4 21.6 21.3 24.8 19.7 25.6 19.6 46.7 12.5 13.1 27.8 31.1 21.2 31.1 13.2 12.7 22.9 31.9 30.3 17.0 19.6 13.1 21.1 20.0 12.0 21.7 21.0 37.7 15.7 22.1 22.7 13.5 28.5 28.7 17.3 12.9 21.4 23.5 34.7 36.9 24.4 16.8 13.8 31.3 55.9 37.2 23.1 16.8 31.0 35.5 29.9 27.9 51.4 42.6 49.0 33.2 53.7 60.5 36.7 40.0 33.5 34.9 30.7 38.2 84.8 43.9 30.3 39.3 80.4 33.7 27.7 34.3 29.2 23.0 35.2 19.2 28.6 34.2 20.6 43.3 31.7 38.3 72.0 18.2 40.2 46.1 25.5 29.9 72.5 48.2 58.6 37.0 37.7 22.9 33.5 51.8 38.6 29.2 23.7 39.3 30.2 30.5 40.0 40.8 49.9 38.2 56.0 52.0 42.4 36.7 55.3 48.0 3.8 82.7 41.3 39.2 88.2 35.9 75.6 34.7 39.1 89.7 69.3 29.9 31.1 9.7 35.2 66.7 44.0 46.5 52.9 12.6 12.7 13.6 16.5 12.5 13.1 13.2 12.7 13.1 13.5 12.9 13.8 20.3 6.4 23.1 3.9 33.7 14.3 26.6 39.8 10.8 17.0 14.9 17.3 6.0 34.3 32.2 23.9 6.2 49.6 19.0 12.3 66.5 54.2 2.4 17.3 12.2 21.3 16.8 12.0 8.4 79.1 29.2 16.7 15.8 17.2 24.1 17.3 14.6 29.6 56.4 6.7 8.1 19.2 40.7 38.4 91.2 3.6 25.7 38.0 16.0 3.7 72.7 30.1 20.6 3.0 5.2 48.7 18.4 19.5 17.6 17.9 27.2 65.0 31.6 18.5 6.6 20.0 15.9 33.1 29.4 12.3 11.9 60.7 17.8 25.3 18.0 29.2 NUDC ENSG00000090273 "Nuclear distribution C, dynein complex regulator" Q9Y266 1 26900238-26946871 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 642.2;Respiratory ciliated cells: 635.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027183, HPA028105" Enhanced Enhanced Cytosol NA NA 140000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA027183: AB_10600086, HPA028105: AB_10601988" "unprognostic (1.40e-1)" "unprognostic (1.74e-2)" "unprognostic (5.61e-2)" "unprognostic (6.52e-3)" "unprognostic (2.30e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (1.21e-6)" "unprognostic (1.11e-1)" "unprognostic (1.61e-1)" "unprognostic (1.78e-1)" "unprognostic (4.12e-2)" "unprognostic (3.82e-1)" "unprognostic (3.26e-2)" "unprognostic (2.90e-2)" "unprognostic (1.55e-1)" "unprognostic (2.53e-1)" "unprognostic (5.10e-2)" 62.6 140.1 108.3 37.7 111.2 51.7 64.2 113.6 124.2 69.3 118.7 97.8 35.8 70.1 70.0 59.7 93.9 28.4 106.7 110.1 115.8 79.8 116.0 63.7 42.3 109.5 110.5 74.5 81.4 53.1 75.4 40.8 110.7 72.1 31.5 48.6 54.5 57.0 126.1 67.1 52.7 41.8 108.6 63.3 85.3 86.7 110.5 47.5 63.2 60.6 42.3 80.0 61.7 120.2 204.2 208.1 106.9 149.2 83.5 74.6 121.2 159.2 97.3 209.4 153.5 192.3 137.8 169.5 137.1 109.6 154.2 156.2 229.5 209.8 160.7 132.1 238.0 210.9 207.7 333.7 147.2 224.9 149.2 80.6 134.5 252.7 161.8 90.9 156.4 194.9 306.1 92.3 143.5 175.9 227.3 289.9 281.2 264.8 266.4 234.7 135.5 172.4 180.1 79.2 177.4 133.1 173.3 109.0 149.1 99.8 106.5 137.0 155.5 148.7 178.1 188.3 207.4 184.0 311.9 202.0 160.4 312.7 170.9 184.4 138.8 141.1 152.7 150.2 154.5 176.7 154.1 145.4 140.7 185.9 150.7 154.9 95.4 147.4 155.1 163.2 163.5 168.0 108.3 111.2 113.6 124.2 110.1 115.8 109.5 110.5 110.7 108.6 110.5 120.2 111.8 134.6 116.1 12.4 93.6 154.1 329.0 187.2 82.0 93.3 85.1 85.9 166.5 137.2 169.8 110.3 52.1 203.3 89.2 91.3 262.2 285.0 85.6 473.8 105.4 120.6 131.4 99.3 16.1 317.4 206.7 128.9 105.5 113.4 147.6 104.5 95.3 642.2 147.5 111.0 16.5 123.1 128.1 70.2 132.1 132.7 135.8 83.7 151.2 11.2 115.3 181.1 86.5 10.1 19.2 309.7 79.7 153.1 77.5 277.7 76.3 200.1 635.8 105.7 111.7 129.1 174.6 246.4 249.7 70.9 148.5 162.7 128.9 91.1 129.1 200.1 NUDT1 MTH1 ENSG00000106268 "Nudix hydrolase 1" P36639 7 2242226-2251146 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 77.6" "Cell type enhanced" "Detected in many" "Late spermatids: 121.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012636 Approved Supported Cytosol No No 21000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA012636: AB_1854696" "unprognostic (1.31e-1)" "unprognostic (1.19e-2)" "unprognostic (2.13e-2)" "unprognostic (2.37e-1)" "unprognostic (3.01e-3)" "unprognostic (3.37e-1)" "prognostic unfavorable (4.44e-4)" "unprognostic (2.15e-2)" "unprognostic (4.77e-1)" "unprognostic (3.81e-2)" "unprognostic (3.81e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (1.30e-7)" "unprognostic (1.29e-1)" "unprognostic (6.71e-2)" "unprognostic (3.49e-2)" "unprognostic (1.70e-1)" 19.1 8.0 13.7 23.8 16.6 77.6 15.0 14.6 18.0 16.9 10.9 19.1 16.2 12.4 5.4 29.1 12.0 10.5 18.7 15.4 13.6 8.9 6.3 12.4 37.1 16.1 14.1 9.3 9.1 3.2 4.4 10.5 15.6 11.3 11.0 4.3 12.4 7.0 21.3 33.8 16.8 9.2 15.0 23.6 12.2 65.5 14.5 59.4 7.6 13.5 31.5 14.6 18.5 17.9 98.4 155.2 83.3 111.0 30.0 41.3 61.0 42.3 36.5 57.0 65.8 84.2 72.1 102.8 33.7 47.0 115.5 117.1 63.8 64.3 33.1 46.2 109.4 80.6 136.3 72.7 7.2 63.2 78.0 27.4 16.7 82.3 29.0 18.6 31.0 147.1 65.0 111.6 64.5 250.2 119.1 245.3 179.5 48.5 94.7 163.5 123.4 86.4 31.7 54.9 83.5 115.6 43.7 126.9 20.8 59.8 83.9 165.8 29.1 54.2 205.1 126.8 102.3 85.2 70.6 108.9 54.6 155.1 199.8 31.5 60.2 44.4 42.8 78.6 34.3 71.0 49.6 45.6 94.3 65.1 48.9 42.3 16.2 39.4 66.8 211.5 75.5 45.7 13.7 16.6 14.6 18.0 15.4 13.6 16.1 14.1 15.6 15.0 14.5 17.9 13.0 6.4 7.5 1.0 34.2 40.1 26.5 22.6 14.8 11.2 25.3 39.0 16.8 10.0 13.7 11.0 4.2 38.5 46.1 39.6 19.6 24.3 54.7 14.9 24.3 12.8 7.8 111.7 0.5 37.4 80.0 29.6 13.7 10.7 61.0 32.4 7.9 5.2 89.4 0.0 0.5 35.7 32.6 46.2 86.7 121.2 22.1 52.6 46.2 0.0 47.1 27.4 47.4 1.0 4.3 20.4 18.4 18.8 33.1 21.5 17.3 14.1 13.0 7.9 32.9 27.5 32.4 70.2 54.8 41.0 37.1 23.7 37.3 13.7 45.1 27.3 NUDT10 "DIPP3a, hDIPP3alpha" ENSG00000122824 "Nudix hydrolase 10" Q8NFP7 X 51332231-51337525 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 26.3" "Group enriched" "Detected in many" 5 "Hepatic stellate cells: 60.3;Peritubular cells: 29.0" "Group enriched" "Detected in many" 6 "glioma: 5.0;prostate cancer: 5.4;testis cancer: 7.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.5;HAP1: 14.2;HEK 293: 10.5;NTERA-2: 25.8;SH-SY5Y: 5.6;U-2 OS: 12.7" "HPA047027, HPA057684" Approved Approved Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA047027: AB_2679907, HPA057684: AB_2683501" "unprognostic (2.61e-2)" "unprognostic (1.12e-2)" "unprognostic (7.40e-3)" "unprognostic (7.84e-2)" "unprognostic (1.82e-1)" "unprognostic (2.51e-2)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (2.54e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-2)" "unprognostic (1.27e-1)" "unprognostic (1.51e-3)" "unprognostic (1.80e-3)" "unprognostic (1.04e-2)" "unprognostic (1.12e-2)" "unprognostic (5.04e-5)" 0.6 1.6 11.2 0.8 9.8 1.5 0.8 3.8 9.8 6.2 2.3 3.1 0.5 5.3 16.1 1.0 3.6 1.4 1.0 9.2 10.0 3.9 1.3 0.3 0.3 5.0 7.1 16.9 0.3 0.0 2.1 0.0 7.1 14.9 0.7 1.5 0.5 14.6 0.1 0.4 1.0 4.1 4.1 3.4 1.2 26.3 11.9 0.4 0.6 0.2 0.3 3.9 3.6 9.3 0.0 0.0 7.5 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.2 0.0 14.2 0.6 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 25.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 12.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 11.2 9.8 3.8 9.8 9.2 10.0 5.0 7.1 7.1 4.1 11.9 9.3 0.2 0.0 1.3 0.7 0.2 1.0 4.9 0.6 1.8 0.5 0.1 1.5 0.2 0.0 0.6 0.0 0.0 0.7 0.4 0.0 0.0 0.0 1.5 0.7 3.5 2.5 0.0 0.8 5.0 0.0 1.0 3.1 0.0 0.1 0.0 5.0 60.3 0.3 0.2 0.0 1.9 0.0 0.0 1.9 0.4 6.2 5.9 0.1 1.8 1.0 0.0 1.7 0.0 3.5 0.6 0.0 0.0 29.0 1.4 2.8 0.0 0.1 0.0 0.5 0.0 1.5 1.9 3.8 7.8 0.4 0.1 0.4 0.2 0.9 0.0 0.2 NUDT11 "DIPP3b, FLJ10628, hDIPP3beta" ENSG00000196368 "Nudix hydrolase 11" Q96G61 X 51490011-51496592 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.3;testis: 36.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 15.3;Late spermatids: 17.1;Peritubular cells: 20.7;Spermatocytes: 14.6;Spermatogonia: 20.3" "Group enriched" "Detected in many" 4 "glioma: 12.1;prostate cancer: 10.6;testis cancer: 17.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HAP1: 69.3;NTERA-2: 42.9" "Low region specificity" "Detected in many" "HPA047027, HPA057684" Approved Approved Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 5: NTERA-2 - Transcription" "Cluster 36: Stromal cells - Cell proliferation" Cytosol "HPA047027: AB_2679907, HPA057684: AB_2683501" "unprognostic (2.01e-1)" "unprognostic (2.57e-1)" "unprognostic (8.21e-2)" "unprognostic (1.93e-3)" "unprognostic (6.61e-2)" "unprognostic (1.13e-3)" "unprognostic (5.52e-3)" "unprognostic (1.25e-1)" "unprognostic (2.25e-2)" "unprognostic (2.18e-1)" "unprognostic (8.41e-2)" "unprognostic (1.33e-1)" "unprognostic (7.80e-12)" "unprognostic (4.34e-4)" "unprognostic (1.17e-2)" "unprognostic (2.78e-1)" "unprognostic (3.94e-4)" 1.0 4.6 11.9 0.9 13.7 1.4 2.1 4.5 14.7 4.0 2.1 2.9 1.1 5.1 3.5 1.3 2.0 1.6 0.5 13.4 20.0 0.5 0.1 0.5 0.6 5.6 7.2 8.9 4.9 0.2 4.3 0.0 8.4 9.1 0.8 2.2 0.7 10.4 0.1 1.2 1.0 4.4 5.6 0.3 1.1 36.2 23.3 2.6 0.6 0.5 0.6 1.9 2.4 7.7 0.0 1.0 20.6 0.0 17.5 22.0 0.1 9.8 2.7 0.5 0.5 0.0 0.0 0.0 0.5 11.9 11.4 1.5 69.3 23.9 0.3 0.0 4.7 0.0 0.0 0.0 8.2 0.0 4.6 13.5 9.3 6.2 22.4 3.9 16.4 21.6 0.1 0.0 19.6 0.5 27.6 0.1 42.9 0.0 17.5 0.0 14.4 0.0 4.3 0.0 0.0 13.4 4.2 0.0 4.0 10.2 0.0 0.1 9.6 4.8 22.4 1.4 0.0 9.0 4.5 15.2 3.1 0.0 1.9 0.0 0.0 0.0 1.2 0.0 0.5 0.1 0.3 0.6 0.1 0.1 0.0 0.9 0.0 0.7 0.1 0.0 0.0 0.3 11.9 13.7 4.5 14.7 13.4 20.0 5.6 7.2 8.4 5.6 23.3 7.7 0.4 0.0 0.0 0.3 0.3 15.3 6.4 12.8 12.0 1.6 0.5 3.9 0.6 0.0 1.6 0.0 0.0 0.3 3.5 0.0 0.0 0.2 11.3 0.5 9.0 0.9 0.0 1.3 6.3 1.5 1.0 7.7 0.0 0.3 0.0 3.4 0.4 0.0 0.1 0.0 3.8 0.0 0.0 0.3 3.8 17.1 8.7 0.6 5.4 2.8 0.0 1.4 3.1 4.0 0.6 1.4 0.0 20.7 0.3 10.4 0.0 0.2 0.2 0.2 0.0 3.0 5.3 14.6 20.3 1.6 9.1 0.3 0.8 7.5 0.0 1.3 NUDT3 DIPP ENSG00000272325 "Nudix hydrolase 3" O95989 6 34279679-34392669 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047027, HPA055953" Uncertain Approved Cytosol NA NA 87000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 5: Muller glia cells - Visual perception" Cytosol "HPA047027: AB_2679907, HPA055953: AB_2682984" "unprognostic (2.42e-1)" "prognostic favorable (5.29e-4)" "unprognostic (9.63e-3)" "unprognostic (4.74e-3)" "unprognostic (3.60e-2)" "unprognostic (1.84e-1)" "unprognostic (1.41e-3)" "unprognostic (4.21e-2)" "unprognostic (4.93e-3)" "unprognostic (1.08e-1)" "unprognostic (3.16e-1)" "unprognostic (4.63e-1)" "unprognostic (1.24e-2)" "unprognostic (3.28e-2)" "unprognostic (1.09e-1)" "unprognostic (1.54e-1)" "unprognostic (6.24e-2)" 12.8 12.9 72.7 11.4 65.3 12.0 14.7 41.2 73.1 17.2 33.8 10.4 9.0 13.2 30.1 12.3 17.3 9.2 20.7 64.9 55.9 18.0 12.1 13.3 13.7 60.8 59.6 19.7 10.5 29.9 5.7 10.4 59.0 12.8 10.9 43.1 11.4 17.5 70.8 13.4 9.4 13.0 64.5 16.5 9.8 7.6 73.7 11.4 25.3 51.8 14.9 9.4 7.4 59.5 11.0 8.0 20.9 41.2 13.7 22.9 8.7 7.9 13.2 8.0 5.7 9.7 7.2 37.3 10.5 14.3 5.1 9.2 11.0 21.3 14.7 14.5 15.2 42.9 10.4 20.7 13.0 41.5 21.7 20.8 18.8 9.0 16.8 9.9 23.2 20.1 42.5 14.0 12.6 11.4 28.7 48.1 13.4 32.5 7.3 24.7 17.4 39.2 18.2 22.7 29.3 32.4 17.5 24.4 32.1 6.0 23.6 28.2 25.7 15.6 5.7 14.1 17.4 11.7 28.7 27.9 9.7 40.1 25.4 1.4 3.9 9.2 2.1 4.1 2.4 2.2 2.1 1.9 4.4 3.0 1.9 2.2 2.8 1.4 4.2 2.1 1.6 1.8 72.7 65.3 41.2 73.1 64.9 55.9 60.8 59.6 59.0 64.5 73.7 59.5 36.6 16.0 26.7 0.0 41.4 59.9 72.2 32.4 51.8 117.0 30.5 27.9 47.5 62.9 25.0 42.3 118.9 34.7 28.2 16.1 13.7 19.2 4.1 25.0 38.6 67.0 49.1 40.8 0.0 28.5 32.0 36.4 19.4 37.2 13.9 30.3 109.6 56.1 76.0 169.9 0.0 29.0 22.4 107.1 79.2 8.1 37.6 65.2 53.4 0.0 90.1 137.4 42.2 0.0 0.0 27.9 16.0 63.2 22.8 90.1 25.3 24.4 46.4 126.6 59.2 68.1 35.0 45.6 83.9 58.4 60.2 19.6 26.5 32.8 31.8 64.7 NUDT4 "DIPP2, DIPP2alpha, DIPP2beta, HDCMB47P, KIAA0487" ENSG00000173598 "Nudix hydrolase 4" Q9NZJ9 12 93377883-93408146 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 361.9;Erythroid cells: 520.6;Muller glia cells: 485.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017593, HPA047027, HPA057684" Approved Approved Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 39: CACO-2 - Unknown function" "Cluster 5: Muller glia cells - Visual perception" Cytosol "HPA017593: AB_1854703, HPA047027: AB_2679907, HPA057684: AB_2683501" "unprognostic (1.44e-2)" "unprognostic (2.15e-1)" "unprognostic (4.40e-3)" "unprognostic (4.25e-1)" "unprognostic (3.08e-3)" "unprognostic (1.42e-1)" "unprognostic (8.12e-2)" "unprognostic (9.09e-3)" "unprognostic (1.88e-1)" "unprognostic (1.51e-1)" "unprognostic (2.60e-2)" "unprognostic (1.96e-1)" "prognostic favorable (1.27e-4)" "unprognostic (1.75e-1)" "unprognostic (2.87e-1)" "unprognostic (5.01e-1)" "unprognostic (8.32e-3)" 61.2 71.8 52.1 31.9 60.4 169.2 48.7 37.3 75.5 52.1 48.5 57.4 26.6 30.9 62.5 34.8 44.5 89.8 161.6 61.4 53.1 130.5 45.1 29.0 34.3 48.2 54.5 150.2 62.9 41.7 26.5 60.1 47.5 78.7 62.9 102.0 129.8 38.2 87.2 19.8 35.4 37.9 42.5 25.7 34.6 32.3 48.8 34.8 57.5 115.6 36.3 78.6 26.0 52.7 24.1 20.4 36.4 41.1 132.5 54.3 45.5 66.0 52.4 37.0 27.2 188.4 58.6 33.7 14.0 53.1 24.3 29.5 102.4 33.2 56.5 51.9 21.6 126.9 17.1 99.3 126.8 66.8 29.3 118.5 109.2 38.3 85.0 186.1 212.9 59.7 130.7 46.0 42.9 24.6 61.9 63.7 57.2 59.4 47.7 50.7 32.5 36.5 45.0 171.7 29.1 37.5 53.6 103.3 153.2 58.2 75.2 85.6 81.6 31.6 18.0 47.9 42.5 25.6 34.2 49.4 16.6 51.8 98.3 9.5 2.2 11.3 2.8 2.8 5.1 4.5 4.2 2.9 2.0 3.8 4.4 4.4 1.9 6.0 2.5 3.2 4.2 1.9 52.1 60.4 37.3 75.5 61.4 53.1 48.2 54.5 47.5 42.5 48.8 52.7 44.0 19.2 42.8 8.1 74.8 116.8 123.1 22.5 178.7 66.9 58.3 39.1 243.9 114.4 31.8 62.5 62.6 188.7 49.8 226.9 361.9 21.8 125.6 45.7 38.2 66.4 152.2 520.6 16.6 16.5 32.9 99.2 36.2 60.6 25.4 54.2 41.7 53.4 43.7 42.1 7.5 89.3 12.2 35.1 81.0 26.2 39.1 47.2 106.7 5.6 34.3 485.7 34.0 10.6 1.3 55.1 92.8 46.6 113.9 137.8 68.2 52.8 86.1 44.5 72.3 184.4 204.4 115.7 17.3 119.2 96.7 163.8 80.2 37.3 90.4 178.4 NUDT4B NUDT4P1 ENSG00000177144 "Nudix hydrolase 4B" A0A024RBG1 1 148748894-148750099 "Enzymes, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 6 "eosinophil: 2.8" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.8" "Cell line enhanced" "Detected in all" "CACO-2: 42.1;RT4: 34.5" "HPA017593, HPA047027, HPA057684" Approved Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 39: CACO-2 - Unknown function" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA017593: AB_1854703, HPA047027: AB_2679907, HPA057684: AB_2683501" "unprognostic (1.24e-1)" "unprognostic (4.01e-2)" 4.9 6.8 0.2 3.6 0.4 23.6 1.8 0.0 0.9 4.4 0.3 5.7 5.3 3.7 2.6 8.1 7.0 17.7 20.8 0.5 0.6 9.8 3.9 2.6 6.8 1.3 0.5 16.1 11.9 4.6 0.3 7.7 0.4 7.5 6.1 0.6 23.6 3.1 5.3 1.3 5.2 3.6 0.3 3.0 4.1 7.7 0.3 3.2 7.9 8.1 3.7 11.1 0.6 0.6 3.5 3.8 1.5 4.7 6.3 5.1 9.3 4.1 6.2 4.4 4.2 42.1 14.8 3.5 1.7 3.7 4.2 5.7 6.8 3.0 2.2 11.0 3.3 8.5 2.3 5.4 8.4 5.8 2.6 10.6 9.7 5.5 5.1 5.3 16.5 4.3 17.6 13.8 4.2 3.0 7.9 1.1 8.3 3.4 6.2 9.7 2.2 10.0 3.2 34.5 3.0 4.4 3.5 8.6 23.7 1.0 11.7 11.0 9.1 5.8 4.5 9.6 6.3 3.2 5.2 4.5 2.7 8.7 17.4 0.0 0.1 2.8 0.0 0.3 0.2 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.4 0.0 0.2 0.2 0.2 0.4 0.0 0.9 0.5 0.6 1.3 0.5 0.4 0.3 0.3 0.6 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 NXN "FLJ12614, NRX" ENSG00000167693 Nucleoredoxin Q6DKJ4 17 799310-979776 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Wnt signaling pathway" "Developmental protein, Oxidoreductase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 99.2" "Cell type enhanced" "Detected in many" "Late spermatids: 91.5;Microglial cells: 87.1;Urothelial cells: 59.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 100.7;HHSteC: 106.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023566 Approved Approved Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA023566: AB_1854737" "unprognostic (1.68e-2)" "unprognostic (1.75e-1)" "unprognostic (1.15e-2)" "unprognostic (3.48e-2)" "unprognostic (7.29e-2)" "unprognostic (1.00e-1)" "unprognostic (1.75e-2)" "unprognostic (6.98e-2)" "unprognostic (1.65e-3)" "unprognostic (2.27e-2)" "unprognostic (3.16e-2)" "unprognostic (1.43e-1)" "unprognostic (5.76e-2)" "unprognostic (3.56e-2)" "unprognostic (2.34e-1)" "unprognostic (2.68e-2)" "unprognostic (2.05e-3)" 16.9 7.5 14.5 8.7 13.1 1.1 19.0 12.1 15.0 41.3 21.9 70.0 5.4 47.2 11.6 27.2 29.1 13.7 16.0 13.5 13.2 14.4 9.5 24.6 5.0 13.6 14.9 14.8 33.6 2.6 6.8 14.5 14.0 39.7 4.6 8.9 20.7 25.0 99.2 24.9 19.8 23.1 12.8 6.4 28.3 9.6 17.1 13.1 12.9 35.7 13.8 43.4 42.5 12.3 14.3 21.2 81.5 52.8 5.3 1.1 4.5 44.6 29.3 46.1 73.3 50.4 14.8 0.6 83.6 57.5 10.8 100.7 52.9 83.2 36.3 0.6 30.9 0.2 12.7 44.8 106.1 0.3 2.3 32.2 75.6 6.0 36.0 9.3 41.9 11.3 7.4 0.0 12.3 5.8 2.9 1.0 39.2 42.3 1.4 6.2 2.1 0.3 32.9 20.6 20.9 13.6 21.1 0.1 1.1 50.3 14.9 13.0 0.0 1.0 19.1 0.4 12.5 7.5 5.2 0.4 0.4 1.7 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.2 0.2 0.0 0.2 0.2 0.0 14.5 13.1 12.1 15.0 13.5 13.2 13.6 14.9 14.0 12.8 17.1 12.3 36.5 32.1 11.7 13.4 0.9 17.5 53.6 18.8 12.0 2.6 7.6 12.4 8.6 2.8 13.2 3.7 33.3 0.4 0.4 0.1 0.0 3.5 25.1 20.2 52.1 34.7 1.8 2.7 6.9 24.6 0.7 23.0 1.1 12.6 1.3 1.0 14.6 8.2 6.3 5.0 10.7 0.0 0.0 0.3 8.8 91.5 15.5 1.9 7.2 87.1 0.6 11.4 0.0 23.1 3.3 5.9 0.0 7.2 0.4 36.0 0.0 0.5 15.5 18.0 13.1 14.5 19.2 13.1 10.1 13.1 12.4 0.4 1.5 27.2 0.0 59.0 NXNL2 "C9orf121, RdCVF2" ENSG00000130045 "Nucleoredoxin like 2" Q5VZ03 9 88534033-88584274 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Early spermatids: 11.4;Endometrial ciliated cells: 39.1;Glandular and luminal cells: 13.9;Granulosa cells: 13.2;Proximal tubular cells: 18.6;Theca cells: 12.7" "Cancer enhanced" "Detected in some" "ovarian cancer: 7.2" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 10.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA045526 Uncertain Approved Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA045526: AB_10961044" "prognostic favorable (6.53e-4)" "unprognostic (9.70e-2)" "unprognostic (4.78e-3)" "prognostic favorable (3.83e-8)" "unprognostic (2.70e-2)" "unprognostic (3.19e-2)" "unprognostic (1.29e-1)" "unprognostic (3.56e-4)" "unprognostic (1.92e-2)" "unprognostic (1.69e-1)" "unprognostic (2.62e-3)" "unprognostic (5.58e-2)" "prognostic favorable (9.60e-4)" "unprognostic (1.37e-1)" "unprognostic (2.52e-2)" "unprognostic (8.49e-2)" "unprognostic (2.36e-2)" 6.5 0.7 4.3 1.2 3.4 4.2 2.8 6.0 5.5 4.0 1.8 0.5 0.9 2.0 1.3 0.4 4.3 1.0 0.7 3.4 3.4 2.3 4.5 0.7 0.9 0.7 1.2 1.1 0.4 0.3 0.1 0.6 1.4 0.9 0.4 4.8 1.6 0.7 1.3 1.5 0.9 0.4 0.4 1.1 0.8 1.3 3.6 0.5 1.3 0.1 0.5 0.4 0.3 5.1 1.5 2.6 1.0 1.0 0.1 0.7 0.7 2.6 0.7 0.3 0.5 0.6 1.0 0.6 1.1 0.3 0.7 1.3 0.4 0.1 0.9 0.4 0.8 1.3 4.0 1.0 0.4 0.7 1.1 0.5 0.2 0.3 0.2 0.4 0.0 0.9 0.9 2.7 0.7 0.7 0.7 1.2 1.4 0.5 0.7 0.5 0.5 0.9 10.4 0.8 0.6 0.4 1.6 0.8 0.5 0.7 1.2 0.6 0.9 0.9 1.9 1.5 0.6 0.9 0.8 0.7 0.7 0.9 0.7 2.1 0.3 0.8 0.6 0.1 0.6 0.2 0.3 0.7 0.0 0.3 0.6 0.7 0.8 0.5 0.1 0.3 0.6 0.3 4.3 3.4 6.0 5.5 3.4 3.4 0.7 1.2 1.4 0.4 3.6 5.1 0.2 0.0 0.0 1.3 0.1 0.0 1.9 0.7 1.2 0.2 7.5 3.2 0.3 4.3 0.1 1.8 0.0 0.2 0.0 0.0 1.9 0.8 11.4 39.1 4.3 0.8 0.0 0.0 1.2 0.2 1.3 0.8 0.0 13.9 0.0 13.2 0.0 0.1 0.2 0.0 1.9 0.0 0.0 0.0 0.0 4.4 0.9 0.2 0.0 0.0 0.0 0.5 0.0 1.0 0.7 0.2 0.0 2.2 0.1 0.4 0.0 18.6 0.2 0.8 0.0 0.3 1.3 0.4 1.6 0.0 0.1 1.1 0.3 12.7 0.0 2.2 OGA "MEA5, MGEA5, NCOAT" ENSG00000198408 O-GlcNAcase O60502 10 101784443-101818465 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 86.5;dendritic cells: 89.3;Glandular and luminal cells: 83.7;Granulosa cells: 69.4;Pancreatic endocrine cells: 82.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036141, HPA076501" Approved Supported Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA036141: AB_10672079, HPA076501: AB_2686802" "unprognostic (4.34e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (8.69e-5)" "unprognostic (4.63e-1)" "unprognostic (2.06e-1)" "unprognostic (2.57e-2)" "unprognostic (2.65e-1)" "unprognostic (1.79e-2)" "unprognostic (2.44e-1)" "unprognostic (1.21e-3)" "unprognostic (6.00e-2)" "unprognostic (7.81e-2)" "unprognostic (1.68e-1)" "unprognostic (3.01e-1)" "unprognostic (3.21e-2)" "unprognostic (1.90e-1)" "unprognostic (9.23e-3)" 65.3 34.1 77.3 46.7 80.3 89.0 59.2 99.3 82.8 62.2 54.3 64.8 28.1 50.0 55.5 57.4 52.9 29.8 60.7 82.2 74.0 45.6 46.0 52.9 69.8 66.8 70.3 66.8 42.9 60.6 44.9 41.0 67.7 52.7 40.7 99.8 50.5 38.9 56.6 72.7 62.8 35.4 68.6 74.4 46.4 38.6 84.3 67.6 51.7 29.5 64.8 57.0 58.6 77.6 89.8 44.7 63.7 124.6 40.0 96.6 44.4 61.7 61.8 28.1 48.0 33.1 56.0 59.6 43.7 73.7 48.2 62.9 60.3 77.5 59.2 87.9 41.2 59.6 65.0 26.0 43.1 44.4 32.3 93.9 85.1 48.1 113.7 80.0 53.0 53.1 42.8 107.3 48.3 45.6 47.2 46.1 35.4 19.4 44.8 64.8 70.5 44.0 47.2 80.0 27.7 48.8 55.2 29.4 78.2 58.0 77.9 47.7 80.9 43.0 41.6 63.0 71.6 53.1 91.0 47.2 54.0 74.6 24.0 14.4 2.1 7.2 6.4 2.0 5.1 6.6 4.5 5.8 1.3 7.5 6.1 5.2 14.1 6.6 6.3 3.3 4.6 1.5 77.3 80.3 99.3 82.8 82.2 74.0 66.8 70.3 67.7 68.6 84.3 77.6 66.3 0.0 0.0 0.0 40.2 0.0 0.0 0.0 0.0 0.0 66.5 47.0 0.0 0.0 0.0 86.5 0.0 41.9 89.3 0.0 13.7 38.0 0.0 61.6 68.3 18.1 0.0 0.0 0.0 40.9 34.3 20.3 0.0 83.7 0.0 69.4 0.0 0.0 39.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.5 0.0 0.0 48.6 0.0 0.0 0.0 0.0 82.4 0.0 0.0 44.3 0.0 0.0 34.0 0.0 0.0 0.0 0.0 28.3 0.0 0.0 0.0 0.0 50.9 34.6 44.8 0.0 0.0 OLA1 "GTPBP9, PTD004" ENSG00000138430 "Obg like ATPase 1" Q9NTK5 2 174072447-174248599 "Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035790, HPA041443" Approved Enhanced Cytosol NA NA 3300000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA035790: AB_10601977, HPA041443: AB_2677483" "unprognostic (3.30e-1)" "unprognostic (1.06e-1)" "unprognostic (2.23e-2)" "unprognostic (2.85e-3)" "unprognostic (1.20e-1)" "unprognostic (3.08e-3)" "prognostic unfavorable (9.73e-8)" "unprognostic (6.51e-3)" "unprognostic (7.66e-2)" "unprognostic (1.09e-2)" "unprognostic (3.50e-3)" "unprognostic (1.63e-1)" "unprognostic (1.13e-3)" "unprognostic (4.32e-2)" "unprognostic (2.51e-2)" "unprognostic (2.62e-2)" "unprognostic (9.75e-2)" 42.2 44.3 39.7 38.2 42.7 53.7 57.3 42.5 48.9 34.3 30.0 48.0 50.1 34.7 38.8 58.1 38.0 35.1 57.4 44.5 43.8 56.4 43.0 23.5 47.9 38.0 36.6 31.1 56.3 44.1 27.4 42.0 40.1 41.1 52.7 42.5 36.3 33.6 105.6 52.0 45.7 37.0 38.0 24.6 35.2 48.8 40.7 58.3 59.7 93.1 53.3 48.3 31.0 39.1 181.4 84.1 134.9 225.5 70.1 152.2 243.0 142.1 142.8 194.2 147.1 200.9 104.4 246.5 138.9 114.5 143.9 139.9 165.3 164.6 227.3 113.7 142.5 231.3 76.4 209.9 135.3 264.3 90.2 134.8 200.6 206.3 217.4 177.4 174.5 88.0 256.8 82.3 170.3 116.6 241.4 272.9 159.1 193.9 273.0 180.4 217.8 170.7 245.1 192.0 218.3 124.7 96.8 141.6 206.2 142.2 101.2 220.6 127.5 127.1 161.4 128.5 210.8 76.2 207.3 190.5 124.6 180.0 115.4 18.1 24.9 7.4 16.2 24.2 23.4 17.9 18.6 20.8 37.1 16.4 21.5 21.2 2.1 26.1 20.0 22.5 25.3 22.7 39.7 42.7 42.5 48.9 44.5 43.8 38.0 36.6 40.1 38.0 40.7 39.1 43.2 35.3 33.0 57.5 49.0 62.7 73.5 92.4 76.8 47.3 86.0 83.8 68.3 47.1 57.0 31.3 35.5 153.7 47.7 44.6 103.7 145.1 267.8 37.1 55.2 47.8 70.7 92.5 132.6 105.3 112.8 53.0 60.1 43.1 41.2 73.3 29.3 25.8 97.3 33.7 129.8 79.6 65.1 59.6 54.4 99.5 40.4 55.9 32.0 65.6 83.1 60.3 52.5 101.6 101.8 112.8 51.8 51.1 56.3 84.2 78.4 141.7 36.1 35.9 26.3 69.7 92.3 104.8 35.9 113.7 64.1 105.9 55.9 94.6 107.6 79.3 OLFML2B DKFZP586L151 ENSG00000162745 "Olfactomedin like 2B" Q68BL8 1 161983192-162023869 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 48.3" "Cell type enhanced" "Detected in many" "Early spermatids: 122.5;Hofbauer cells: 38.4;Skeletal myocytes: 175.5;Smooth muscle cells: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "intermediate monocyte: 6.7;non-classical monocyte: 5.5" "Lineage enriched" "Detected in single" 11 "monocytes: 6.7" "Cell line enhanced" "Detected in many" "ASC TERT1: 39.7;HSkMC: 113.3;RH-30: 88.5" "Group enriched" "Detected in all" 4 "hippocampal formation: 41.0;white matter: 11.9" "Low region specificity" "Detected in all" "HPA054136, HPA062739" Approved Approved Cytosol "Secreted - unknown location" NA NA 12000 "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA054136: AB_2682397, HPA062739: AB_2684858" "unprognostic (2.97e-2)" "unprognostic (1.79e-1)" "unprognostic (8.91e-2)" "unprognostic (1.05e-1)" "unprognostic (6.01e-2)" "unprognostic (1.22e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (5.97e-3)" "unprognostic (7.32e-2)" "unprognostic (7.68e-3)" "unprognostic (1.16e-1)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.01e-12)" "unprognostic (1.64e-3)" "unprognostic (2.11e-2)" "unprognostic (4.53e-3)" "unprognostic (1.97e-2)" 23.4 6.9 4.2 19.2 7.5 0.4 14.7 2.4 5.6 16.8 6.0 18.3 2.1 16.2 5.0 3.9 11.4 48.3 6.6 5.7 3.4 3.1 0.8 15.3 14.0 3.7 4.0 4.2 1.4 3.5 2.8 40.6 4.7 5.3 2.9 0.2 10.4 6.9 10.2 10.1 5.5 22.0 3.0 10.2 3.3 15.9 9.8 3.7 20.8 6.5 11.2 16.8 7.3 4.2 0.1 0.4 6.6 2.2 21.0 39.7 0.0 2.3 10.6 4.3 11.8 0.0 0.2 0.0 0.3 25.7 4.3 0.0 0.6 0.1 2.5 0.0 0.8 0.5 0.2 0.0 0.3 0.1 0.8 113.3 0.0 5.3 0.0 2.1 0.7 0.0 0.0 1.0 19.3 0.1 0.1 0.2 2.1 0.0 1.0 0.2 88.5 8.9 1.6 0.1 0.8 0.3 9.1 0.0 0.6 19.6 0.0 0.1 0.1 2.7 0.7 4.0 3.6 0.0 0.1 0.0 25.1 2.7 1.3 0.0 0.4 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 5.5 0.0 0.0 0.2 4.2 7.5 2.4 5.6 5.7 3.4 3.7 4.0 4.7 3.0 9.8 4.2 4.1 0.0 0.6 0.0 0.2 3.3 0.1 0.1 0.0 0.1 0.4 1.0 3.0 1.5 0.7 1.8 0.0 0.3 0.1 0.0 0.0 0.0 122.5 1.2 24.9 1.7 0.0 0.4 2.8 0.0 0.3 21.9 0.0 0.7 1.3 1.1 1.1 0.2 38.4 0.0 0.9 0.1 0.0 31.1 9.0 12.9 20.8 16.6 1.8 8.4 0.9 0.8 0.0 0.0 2.9 0.0 0.0 29.3 0.1 0.1 0.0 0.1 0.1 0.1 6.6 175.5 57.2 8.8 1.7 0.1 2.3 0.3 0.6 16.4 0.0 0.0 OPTN "FIP-2, FIP2, GLC1E, HIP7, HYPL, NRP, TFIIIA-INTP" ENSG00000123240 Optineurin Q96CV9 10 13099449-13138308 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, Host-virus interaction, Immunity, Innate immunity" "Amyotrophic lateral sclerosis, Disease variant, Glaucoma, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "skeletal muscle: 879.4;tongue: 394.5" "Cell type enhanced" "Detected in all" "Late spermatids: 933.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003279, HPA003360, CAB019303" Approved Enhanced Cytosol NA NA 370000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "CAB019303: , HPA003279: AB_1079527, HPA003360: AB_1079528" "unprognostic (2.84e-2)" "unprognostic (3.37e-1)" "unprognostic (3.79e-3)" "unprognostic (6.46e-3)" "unprognostic (5.58e-2)" "unprognostic (3.74e-2)" "unprognostic (5.15e-3)" "unprognostic (3.14e-2)" "unprognostic (2.68e-2)" "unprognostic (2.16e-1)" "unprognostic (1.40e-2)" "unprognostic (6.14e-1)" "prognostic unfavorable (5.81e-5)" "unprognostic (7.62e-2)" "unprognostic (5.67e-2)" "unprognostic (7.93e-2)" "unprognostic (2.09e-2)" 92.7 90.4 45.7 35.8 53.5 50.1 64.0 45.9 55.9 52.3 36.8 55.4 63.2 39.7 21.9 61.8 37.7 41.6 105.7 54.9 49.2 72.3 73.8 58.9 45.7 48.0 53.9 92.1 35.4 33.1 33.8 57.5 52.9 34.1 57.2 48.8 46.3 41.4 879.4 77.9 69.6 43.4 44.3 57.3 56.1 72.8 45.4 30.1 27.1 394.5 37.6 43.8 56.3 49.0 83.3 23.1 12.8 17.8 171.4 175.6 15.2 97.6 110.7 72.1 119.0 41.1 108.1 0.7 37.6 134.3 113.2 75.6 17.3 93.5 54.8 192.9 9.2 17.2 32.1 22.0 175.4 0.6 59.5 94.6 72.6 69.2 71.8 177.9 62.4 23.8 21.5 123.7 98.7 17.6 8.3 2.3 5.2 22.4 10.3 1.4 25.5 8.5 87.9 57.6 2.8 13.6 84.9 25.0 64.3 49.9 54.6 11.4 171.6 58.8 28.9 81.0 27.5 63.3 23.5 0.6 88.3 14.3 11.4 47.9 2.5 0.3 56.1 1.5 43.3 18.0 71.2 65.8 0.5 11.7 28.0 34.5 1.7 51.2 3.8 5.2 109.6 30.2 45.7 53.5 45.9 55.9 54.9 49.2 48.0 53.9 52.9 44.3 45.4 49.0 68.2 67.3 29.4 18.6 25.9 74.4 46.6 104.5 67.2 38.7 30.5 32.9 237.7 68.6 81.3 31.3 18.8 112.8 89.8 199.8 33.2 135.5 281.9 36.0 38.6 82.4 42.6 126.5 48.9 114.0 39.8 91.6 88.7 37.4 70.8 92.8 47.8 30.9 31.6 90.9 26.6 106.4 65.1 15.1 26.0 933.6 95.7 14.5 90.7 25.3 36.6 36.4 119.4 13.6 28.1 166.3 186.9 103.4 86.3 92.3 209.9 162.4 73.7 103.4 111.7 63.1 106.6 102.0 13.7 58.1 77.9 75.4 107.5 166.3 44.1 75.0 OSBP2 "KIAA1664, ORP-4, ORP4, OSBPL1" ENSG00000184792 "Oxysterol binding protein 2" Q969R2 22 30693782-30907824 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 52.7;retina: 160.8" "Cell type enhanced" "Detected in many" "Early spermatids: 135.4;Excitatory neurons: 132.8;Inhibitory neurons: 156.3;Late spermatids: 304.4;Oligodendrocytes: 182.8;Rod photoreceptor cells: 619.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 41.9;HeLa: 146.4;hTERT-HME1: 38.2;SiHa: 39.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021514 Uncertain Approved Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol "HPA021514: AB_1854813" "unprognostic (2.89e-1)" "unprognostic (2.04e-1)" "unprognostic (2.83e-1)" "unprognostic (6.94e-3)" "unprognostic (2.61e-1)" "unprognostic (1.10e-1)" "unprognostic (1.38e-5)" "unprognostic (3.01e-1)" "unprognostic (2.57e-1)" "unprognostic (2.79e-2)" "unprognostic (1.39e-1)" "unprognostic (2.31e-1)" "prognostic favorable (3.79e-6)" "unprognostic (9.00e-2)" "unprognostic (2.68e-1)" "unprognostic (2.93e-1)" "unprognostic (1.53e-2)" 1.4 11.8 6.2 2.8 14.4 52.7 1.5 17.0 20.5 1.6 2.1 1.7 7.5 2.0 14.6 3.7 2.0 3.0 12.2 8.5 4.4 2.6 1.0 1.6 2.3 9.6 9.8 1.6 5.0 9.3 20.9 4.6 10.0 2.3 1.7 160.8 2.9 2.4 2.8 5.4 5.6 1.2 1.8 4.8 3.5 28.7 21.3 0.6 3.2 3.2 1.3 4.4 2.1 15.1 7.1 15.4 1.5 6.7 1.0 5.8 1.6 1.3 3.1 4.8 4.8 14.0 3.9 12.5 5.7 1.9 1.5 4.1 6.2 0.6 3.5 6.7 1.8 41.9 146.4 2.7 0.9 0.2 2.5 0.3 16.8 11.8 38.2 1.6 12.1 4.8 26.7 0.5 11.0 7.8 1.3 4.5 3.8 3.3 13.8 3.5 0.5 0.7 0.6 2.7 16.7 6.8 39.2 4.1 0.4 2.9 4.9 2.2 8.8 3.4 18.1 3.2 6.8 3.2 4.8 2.3 13.3 0.0 2.7 0.0 0.7 0.4 0.5 1.1 1.0 0.5 1.0 0.4 0.6 0.6 1.0 1.1 0.7 1.0 0.9 0.2 0.7 2.0 6.2 14.4 17.0 20.5 8.5 4.4 9.6 9.8 10.0 1.8 21.3 15.1 1.2 0.0 3.1 37.9 0.2 5.2 0.9 0.4 0.6 93.2 1.3 0.8 11.2 2.8 1.0 1.8 81.3 0.2 0.3 1.3 1.9 1.8 135.4 1.6 0.5 2.8 7.2 91.3 132.8 1.5 0.2 1.6 2.0 1.6 0.0 3.2 0.4 0.1 0.2 18.5 156.3 2.8 0.0 0.3 1.8 304.4 2.5 1.7 1.8 8.4 0.4 31.4 0.0 35.7 182.8 0.8 5.2 1.9 1.4 1.2 0.7 0.8 1.3 619.5 0.0 1.1 2.3 48.6 4.4 1.4 9.5 0.3 0.5 1.2 1.2 1.3 OSBPL2 "DFNA67, KIAA0772, ORP-2" ENSG00000130703 "Oxysterol binding protein like 2" Q9H1P3 20 62231922-62296213 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Lipid transport, Transport" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 94.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 94.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041127, HPA042659" Uncertain Approved Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "HPA041127: AB_10962008, HPA042659: AB_10960683" "unprognostic (1.00e-3)" "unprognostic (7.20e-3)" "unprognostic (1.31e-1)" "unprognostic (6.00e-2)" "unprognostic (1.82e-1)" "unprognostic (1.73e-3)" "unprognostic (3.79e-2)" "unprognostic (9.60e-2)" "unprognostic (6.22e-2)" "unprognostic (1.50e-1)" "unprognostic (1.73e-1)" "unprognostic (6.82e-3)" "prognostic favorable (4.20e-5)" "unprognostic (3.86e-2)" "unprognostic (8.13e-2)" "unprognostic (4.00e-1)" "unprognostic (3.32e-2)" 14.6 15.2 21.1 13.4 21.2 32.9 18.9 38.9 21.4 21.9 20.0 24.3 22.8 14.0 15.8 40.7 15.6 20.0 25.4 16.6 20.3 20.8 18.0 16.2 14.3 23.7 24.0 15.8 39.7 26.4 26.4 13.7 22.3 19.8 22.7 14.5 24.9 18.8 18.0 43.5 21.6 17.4 19.4 24.9 27.9 14.9 29.8 17.2 21.9 11.9 20.4 23.1 29.8 19.4 23.9 17.0 19.6 18.3 19.4 19.1 18.5 14.2 27.9 46.6 32.1 61.0 24.1 11.5 37.1 28.4 41.8 40.7 18.9 42.4 25.7 13.7 17.7 30.6 21.5 31.2 19.0 11.8 26.6 17.7 61.0 20.8 23.3 22.1 19.1 29.4 20.3 21.2 13.5 19.4 17.2 19.8 6.4 43.5 15.0 15.9 23.5 15.3 23.6 48.2 25.6 16.7 25.7 48.2 24.3 25.9 32.1 21.0 13.2 23.2 17.0 24.7 17.3 24.5 37.4 17.5 25.7 8.4 14.9 16.1 9.2 34.5 13.0 11.7 11.4 13.7 10.5 13.7 9.9 10.9 9.5 11.4 94.6 16.8 9.9 7.1 17.5 10.9 21.1 21.2 38.9 21.4 16.6 20.3 23.7 24.0 22.3 19.4 29.8 19.4 27.1 16.0 18.3 17.3 16.5 20.1 24.8 24.4 14.2 18.9 24.7 16.6 61.2 15.7 28.2 11.0 6.2 13.4 21.6 44.5 31.3 22.7 33.0 22.6 12.0 18.1 16.3 24.2 13.9 20.1 14.8 17.8 42.8 34.2 10.8 19.2 12.8 14.1 12.3 18.5 21.7 29.6 22.4 11.1 8.0 17.4 17.4 14.3 8.8 10.3 16.8 18.2 27.8 9.0 15.5 39.8 37.0 13.2 21.9 38.8 30.2 14.1 34.3 15.9 13.1 14.8 13.1 22.8 11.1 25.2 27.8 37.1 18.5 12.0 25.7 58.7 OSTF1 "bA235O14.1, OSF, SH3P2" ENSG00000134996 "Osteoclast stimulating factor 1" Q92882 9 75088514-75147265 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 329.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 302.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020514 Approved Supported Cytosol NA NA 580000 "Cluster 49: Eosinophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" Cytosol "HPA020514: AB_2670461" "unprognostic (1.41e-1)" "unprognostic (3.69e-2)" "unprognostic (7.54e-2)" "prognostic favorable (3.67e-5)" "unprognostic (1.36e-1)" "unprognostic (2.43e-1)" "unprognostic (9.73e-2)" "unprognostic (1.48e-2)" "unprognostic (2.40e-1)" "unprognostic (1.91e-1)" "unprognostic (5.68e-3)" "unprognostic (3.76e-1)" "unprognostic (7.89e-2)" "unprognostic (6.36e-3)" "unprognostic (9.87e-2)" "unprognostic (3.42e-2)" "unprognostic (1.53e-1)" 44.3 36.9 27.8 65.7 35.0 56.3 34.9 32.0 37.2 34.1 25.4 42.5 38.2 22.7 38.2 104.8 20.0 42.8 32.0 28.3 33.2 34.6 57.7 56.4 74.9 31.0 32.5 16.0 19.4 72.1 19.1 69.9 33.1 22.7 45.8 12.3 38.5 19.6 9.5 63.1 47.8 28.8 30.8 87.0 40.6 18.0 31.0 47.8 29.0 16.0 85.0 55.3 53.9 35.1 69.1 16.0 7.7 11.2 45.4 41.7 81.3 71.9 46.9 26.9 24.4 8.2 50.8 70.9 35.3 59.2 34.6 111.8 12.9 51.9 77.0 302.0 16.0 39.3 24.8 42.5 36.7 71.5 141.6 29.1 49.2 31.6 21.8 23.7 91.2 59.4 13.4 158.4 65.4 35.9 107.5 44.8 14.5 161.5 30.8 20.1 52.3 63.0 57.0 97.1 6.5 0.6 53.1 74.1 36.2 58.2 97.4 79.9 86.4 55.8 19.4 108.3 30.8 30.1 52.5 26.7 67.1 81.9 46.4 359.5 177.7 464.8 158.6 199.3 169.6 101.2 110.5 131.5 148.7 87.4 62.1 109.8 495.2 168.4 256.8 110.6 163.0 283.0 27.8 35.0 32.0 37.2 28.3 33.2 31.0 32.5 33.1 30.8 31.0 35.1 113.4 22.4 24.4 8.1 90.8 82.2 61.2 78.2 61.5 2.9 38.6 23.2 7.8 28.6 51.2 33.1 6.2 125.5 162.1 64.8 76.3 49.7 11.9 42.8 59.4 60.5 27.2 23.3 32.0 52.3 252.9 42.1 31.1 51.1 137.6 4.2 71.7 32.2 233.1 10.1 12.6 31.9 69.2 167.4 181.5 6.0 23.9 155.7 76.5 43.1 329.9 6.0 268.8 30.2 67.3 60.5 97.7 15.4 83.2 34.1 64.1 63.0 27.3 8.6 19.7 15.9 45.0 6.7 17.8 141.4 114.5 133.9 163.8 37.6 38.2 91.6 OTOGL "C12orf64, FLJ90579" ENSG00000165899 "Otogelin like" Q3ZCN5 12 80099537-80380880 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 1.9;kidney: 5.1" "Group enriched" "Detected in some" 5 "Excitatory neurons: 51.2;Oligodendrocyte precursor cells: 42.3" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 1.3;U-87 MG: 2.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "basal ganglia: 4.2" "HPA040364, HPA053392" Uncertain Approved Cytosol "Secreted in other tissues" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA040364: AB_10795365, HPA053392: AB_2682135" "unprognostic (2.43e-1)" "unprognostic (2.78e-2)" "unprognostic (2.55e-2)" "unprognostic (1.50e-1)" "unprognostic (5.99e-2)" "unprognostic (3.10e-1)" "unprognostic (3.34e-3)" "unprognostic (4.76e-2)" "unprognostic (2.72e-2)" "unprognostic (4.52e-2)" "unprognostic (2.79e-2)" "unprognostic (1.57e-1)" "unprognostic (1.95e-5)" "unprognostic (1.41e-1)" "unprognostic (1.11e-1)" "unprognostic (2.79e-2)" "unprognostic (2.04e-2)" 0.1 0.0 0.5 0.0 0.7 0.0 0.1 0.0 1.0 0.1 0.0 0.4 0.0 0.1 0.1 0.1 0.1 0.1 1.9 0.3 0.0 5.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.3 0.5 0.1 0.1 0.1 0.5 0.0 0.1 0.4 0.0 0.1 0.2 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.3 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.3 0.0 0.0 2.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.0 1.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 8.8 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 1.4 0.1 0.1 0.2 0.0 0.0 51.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.9 0.0 0.0 0.0 42.3 1.6 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 OTUD4 "DUBA6, HSHIN1, KIAA1046" ENSG00000164164 "OTU deubiquitinase 4" Q01804 4 145110838-145180589 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 185.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036623 Uncertain Supported Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Cytosol "HPA036623: AB_10696780" "unprognostic (1.67e-1)" "unprognostic (4.18e-2)" "unprognostic (3.41e-2)" "unprognostic (1.95e-1)" "unprognostic (2.80e-1)" "unprognostic (4.06e-2)" "unprognostic (3.42e-2)" "unprognostic (2.66e-2)" "unprognostic (1.21e-1)" "unprognostic (1.74e-2)" "unprognostic (5.21e-3)" "unprognostic (2.03e-2)" "unprognostic (1.74e-1)" "unprognostic (1.35e-1)" "unprognostic (1.90e-1)" "unprognostic (3.01e-1)" "unprognostic (2.62e-1)" 14.0 12.8 9.6 13.8 12.3 32.0 12.6 13.0 12.5 12.2 11.0 11.6 11.5 13.6 14.2 13.4 16.1 12.3 11.8 9.9 8.7 11.9 20.2 15.3 16.2 9.1 9.1 14.5 12.2 17.1 9.7 15.1 9.5 10.2 12.1 17.0 11.0 11.4 40.4 15.4 11.2 13.7 8.7 16.2 10.8 31.9 9.4 16.4 13.6 40.4 14.3 18.7 12.1 14.9 28.2 15.7 18.3 17.1 21.3 25.8 24.5 24.0 26.9 30.2 23.9 16.9 33.8 51.2 10.6 33.8 18.5 16.6 31.9 33.6 39.3 22.0 15.0 24.7 20.1 15.8 24.9 52.3 17.7 20.3 33.5 36.9 48.3 25.4 27.1 22.0 41.5 37.3 30.1 16.8 32.4 22.7 20.5 27.0 17.7 26.3 20.0 12.1 29.4 20.1 17.7 14.6 22.2 33.0 24.3 24.1 11.0 21.2 33.1 33.8 21.5 17.7 32.2 27.2 28.7 33.0 23.4 36.5 33.4 0.0 0.4 0.8 0.9 0.6 0.6 0.8 0.6 0.7 0.4 0.6 0.6 0.6 0.1 0.5 0.8 0.7 0.5 0.3 9.6 12.3 13.0 12.5 9.9 8.7 9.1 9.1 9.5 8.7 9.4 14.9 24.8 64.1 23.5 27.7 19.6 63.2 55.3 13.9 18.2 16.1 20.3 11.8 20.2 22.8 20.5 27.6 25.0 21.5 28.2 16.3 9.8 12.7 185.2 52.8 29.1 44.7 15.1 21.4 36.4 14.7 21.4 30.3 14.8 45.7 20.3 19.6 21.0 24.0 12.7 6.7 30.8 15.2 20.3 20.8 42.4 82.4 20.2 23.6 32.0 30.0 17.7 8.3 11.3 40.2 53.7 23.9 11.7 30.1 20.1 64.7 13.1 7.7 45.3 20.9 0.0 39.4 24.2 27.9 48.5 27.4 54.4 16.0 22.9 20.7 15.6 60.4 OXSR1 "KIAA1101, OSR1" ENSG00000172939 "Oxidative stress responsive kinase 1" O95747 3 38165089-38255484 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008237, CAB017181" Supported Enhanced Cytosol NA NA 300000 "Cluster 38: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 41: Macrophages - Immune response" Cytosol "CAB017181: , HPA008237: AB_1079540" "unprognostic (2.16e-1)" "unprognostic (2.36e-2)" "unprognostic (1.79e-2)" "unprognostic (4.55e-3)" "unprognostic (9.89e-2)" "unprognostic (1.97e-2)" "unprognostic (3.53e-3)" "unprognostic (4.05e-2)" "unprognostic (4.44e-1)" "unprognostic (6.06e-2)" "unprognostic (3.95e-3)" "unprognostic (1.88e-2)" "unprognostic (1.87e-3)" "unprognostic (1.56e-1)" "unprognostic (3.14e-2)" "unprognostic (1.71e-1)" "unprognostic (6.99e-3)" 18.4 17.2 9.7 15.7 10.0 33.8 15.6 13.6 12.5 17.8 13.0 18.3 15.2 14.8 15.6 34.1 12.8 15.1 16.9 9.9 10.8 21.5 18.6 15.5 18.5 11.0 11.0 16.1 12.1 26.3 11.5 16.5 11.1 16.5 19.7 13.0 15.2 16.3 36.7 19.5 15.7 17.6 10.2 15.0 16.8 14.1 11.0 25.1 14.8 35.4 23.4 26.7 21.1 11.2 48.5 21.9 42.5 29.8 29.0 33.3 48.2 41.9 57.1 59.2 63.8 28.3 30.8 53.4 20.8 50.5 25.4 29.4 57.8 43.1 77.5 57.6 24.5 58.6 46.1 31.1 34.6 36.6 34.2 26.6 49.6 54.8 87.8 55.7 37.5 67.7 45.2 29.9 102.7 13.7 71.1 26.4 44.8 31.2 26.1 24.2 35.7 41.4 36.4 36.4 22.0 34.0 45.9 114.2 29.0 46.3 37.7 23.7 34.4 37.0 36.6 56.8 63.0 22.7 29.0 38.7 50.7 44.6 75.3 6.8 1.6 3.9 1.8 2.8 1.9 1.0 2.2 1.7 2.6 1.2 1.7 2.1 3.2 3.1 2.5 1.4 2.8 0.9 9.7 10.0 13.6 12.5 9.9 10.8 11.0 11.0 11.1 10.2 11.0 11.2 19.0 12.8 25.8 46.7 27.3 44.1 35.5 25.3 26.7 13.3 19.4 16.5 32.6 4.3 27.6 27.6 20.9 12.1 27.4 44.0 19.6 28.4 3.9 39.9 32.1 19.0 24.1 29.7 59.6 14.5 21.0 18.4 90.7 91.2 15.8 24.9 14.6 20.5 14.9 21.9 51.9 24.5 10.2 29.8 79.0 2.3 9.6 58.0 7.2 29.0 35.2 8.0 18.6 44.7 42.8 46.5 29.4 12.8 19.5 56.5 27.0 22.5 16.1 7.0 13.1 23.7 22.6 15.1 18.5 41.9 51.9 33.0 29.6 19.6 21.6 115.3 P2RX5 "LRH-1, P2X5" ENSG00000083454 "Purinergic receptor P2X 5" Q93086 17 3672199-3696240 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.7;lymphoid tissue: 78.2" "Group enriched" "Detected in some" 4 "B-cells: 94.6;Plasma cells: 29.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 19 "memory B-cell: 76.4;naive B-cell: 84.8" "Lineage enriched" "Detected in many" 20 "B-cells: 84.8" "Cell line enhanced" "Detected in many" "Daudi: 53.2;Karpas-707: 32.7;RPMI-8226: 59.5;U-698: 47.1" "HPA021948, HPA067827" Supported Supported Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Cytosol "HPA021948: AB_1854878, HPA067827: AB_2685908" "unprognostic (1.08e-3)" "unprognostic (9.16e-2)" "unprognostic (1.40e-2)" "unprognostic (5.81e-2)" "unprognostic (1.79e-1)" "unprognostic (1.06e-1)" "unprognostic (8.33e-2)" "unprognostic (4.34e-1)" "unprognostic (1.24e-1)" "unprognostic (1.14e-1)" "unprognostic (2.15e-1)" "unprognostic (2.42e-2)" "unprognostic (1.99e-8)" "unprognostic (1.60e-1)" "unprognostic (1.00e-1)" "unprognostic (3.50e-2)" "unprognostic (3.63e-2)" 0.8 0.3 1.8 30.4 2.2 9.4 0.8 0.2 2.7 0.3 0.0 2.4 1.5 0.1 0.0 0.7 0.3 1.3 8.0 2.1 0.9 0.7 0.5 1.4 78.2 0.6 0.5 0.0 0.2 0.2 1.2 0.2 0.7 0.5 1.9 0.4 1.8 0.0 17.5 0.0 24.7 0.5 0.1 54.4 3.4 0.7 1.1 12.1 0.9 4.0 53.9 2.7 0.3 1.4 8.3 6.7 0.0 0.0 0.2 1.3 0.0 8.4 3.9 0.9 2.6 5.5 9.8 53.2 4.9 4.2 2.9 4.3 18.8 0.0 1.7 0.9 3.2 2.7 17.5 6.3 1.2 3.6 4.2 2.1 1.8 0.2 12.4 6.5 0.0 12.2 0.5 32.7 18.2 0.0 23.4 8.1 4.9 4.4 20.5 0.8 0.0 59.5 0.2 6.3 4.3 0.0 7.5 2.5 3.9 0.0 2.0 3.3 0.1 0.0 4.5 0.2 1.5 11.0 25.2 47.1 0.0 5.1 0.5 0.0 0.1 2.0 3.1 0.0 4.2 76.4 2.8 2.2 0.4 84.8 0.3 0.3 0.0 0.0 0.0 0.1 1.9 4.5 1.8 2.2 0.2 2.7 2.1 0.9 0.6 0.5 0.7 0.1 1.1 1.4 0.1 0.0 0.6 0.0 94.6 0.4 0.1 0.0 0.0 0.8 0.1 0.1 2.7 0.0 0.0 1.8 0.0 0.0 13.4 0.0 0.0 0.2 4.8 0.2 0.2 0.7 0.0 11.1 0.0 0.2 0.0 0.3 0.5 0.3 4.5 0.0 1.4 0.4 0.2 0.0 0.0 0.1 0.0 1.2 0.0 3.1 1.5 1.6 3.6 0.0 1.1 0.0 2.1 0.0 0.0 1.5 0.0 0.0 29.7 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.9 1.0 0.8 0.0 0.0 0.0 11.0 0.0 0.1 0.1 P2RY2 P2U ENSG00000175591 "Purinergic receptor P2Y2" P41231 11 73218281-73242427 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 29.7;skeletal muscle: 50.2;tongue: 31.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 16.5;Distal enterocytes: 18.0;Pancreatic endocrine cells: 18.9;Proximal enterocytes: 14.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 57.6" "Group enriched" "Detected in many" 12 "granulocytes: 57.6;monocytes: 20.2" "Cell line enhanced" "Detected in many" "HaCaT: 32.8;HL-60: 30.8;MCF7: 25.1;NB-4: 26.1;PC-3: 24.5;SK-BR-3: 29.6;THP-1: 76.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB022642 Uncertain Uncertain Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 43: THP-1 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "CAB022642: " "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "unprognostic (6.36e-2)" "unprognostic (7.97e-3)" "unprognostic (6.50e-4)" "unprognostic (2.04e-2)" "unprognostic (4.66e-3)" "unprognostic (8.93e-2)" "unprognostic (2.87e-1)" "unprognostic (4.17e-2)" "prognostic unfavorable (2.19e-5)" "unprognostic (9.69e-2)" "unprognostic (4.92e-4)" "unprognostic (1.34e-1)" "unprognostic (2.82e-1)" "unprognostic (1.05e-1)" "unprognostic (8.57e-3)" 0.8 3.8 1.4 1.8 1.6 15.8 1.7 1.3 1.0 6.9 1.1 3.3 2.7 0.5 0.3 29.7 1.4 0.7 10.0 1.3 1.8 2.7 3.9 3.5 0.1 2.1 1.9 0.4 0.7 4.8 1.6 2.0 1.6 2.1 2.8 1.2 6.2 1.2 50.2 6.0 5.9 0.5 1.3 3.9 1.1 1.2 2.6 0.2 8.8 31.3 2.8 2.2 19.0 1.4 7.2 6.7 0.0 0.0 0.0 0.0 2.4 0.1 0.0 0.0 0.0 17.2 5.4 0.0 10.4 0.4 0.0 32.8 0.9 15.2 0.0 0.0 0.6 2.3 0.6 3.2 0.1 30.8 0.0 0.0 6.8 2.3 0.5 0.0 1.4 0.0 1.4 0.0 0.0 25.1 0.1 26.1 0.4 6.8 24.5 0.0 0.0 1.1 2.4 17.9 0.0 0.0 0.5 29.6 0.0 0.2 12.9 76.5 10.2 0.0 0.3 0.0 0.0 1.0 0.4 0.0 0.0 5.6 0.0 0.5 6.6 57.6 0.0 20.2 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.3 0.0 13.5 0.0 0.0 2.5 1.4 1.6 1.3 1.0 1.3 1.8 2.1 1.9 1.6 1.3 2.6 1.4 0.7 3.2 0.5 0.0 0.2 3.7 8.6 13.2 1.2 0.7 2.8 0.5 6.1 5.7 10.3 0.0 0.0 16.5 0.0 18.0 1.9 5.8 6.0 1.4 0.1 1.5 0.0 0.8 0.0 6.3 1.3 0.7 0.5 0.8 0.0 1.2 0.0 5.2 2.6 0.0 0.0 5.1 0.0 3.7 0.7 8.8 0.0 4.5 0.0 0.0 2.8 6.0 0.0 0.0 0.1 18.9 10.9 0.0 0.2 5.3 14.2 0.3 2.8 0.4 0.0 0.8 1.4 0.1 0.1 12.6 7.2 10.9 0.1 0.1 3.0 11.7 PA2G4 ENSG00000170515 "Proliferation-associated 2G4" Q9UQ80 12 56104537-56113910 "Enzymes, Plasma proteins, Predicted intracellular proteins" "rRNA processing, Transcription, Transcription regulation, Translation regulation" "Repressor, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011711, CAB012428, HPA016484" Supported Approved Cytosol NA NA 2300000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "CAB011711: AB_732060, CAB012428: , HPA016484: AB_1854912" "unprognostic (5.53e-2)" "unprognostic (1.06e-1)" "unprognostic (2.35e-2)" "unprognostic (2.34e-2)" "unprognostic (3.87e-1)" "unprognostic (6.03e-3)" "prognostic unfavorable (6.31e-7)" "unprognostic (4.25e-3)" "unprognostic (2.77e-1)" "unprognostic (3.79e-3)" "unprognostic (2.29e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (4.59e-7)" "unprognostic (1.17e-1)" "unprognostic (2.01e-1)" "unprognostic (1.32e-1)" "unprognostic (4.67e-2)" 78.4 59.6 46.7 89.3 50.4 132.9 76.2 50.7 58.0 64.8 43.0 78.7 74.1 64.7 48.2 132.5 64.7 43.7 76.9 48.6 51.8 62.1 72.8 62.5 96.6 49.4 48.3 71.2 75.1 83.7 36.3 69.2 51.0 53.2 90.5 38.3 63.9 55.4 144.0 106.1 69.7 68.4 49.8 61.2 65.5 63.1 48.9 123.4 61.4 92.5 120.7 105.3 76.9 57.2 429.6 374.8 248.9 275.5 112.5 169.8 499.6 441.3 209.7 530.9 293.8 464.7 307.5 850.8 291.2 209.6 155.9 343.5 574.2 493.1 510.9 243.9 517.6 659.1 242.5 400.4 219.7 898.8 232.4 172.5 247.2 460.2 410.8 218.1 327.3 292.0 812.8 380.7 294.7 383.5 700.8 496.2 410.9 264.5 460.9 569.3 449.8 577.2 272.0 315.7 372.8 225.6 290.5 451.6 275.0 183.1 488.7 343.5 264.8 256.3 364.7 300.3 495.5 234.4 345.1 822.1 232.3 532.6 340.9 34.3 87.0 54.6 129.9 96.0 174.7 98.0 136.8 141.3 102.1 81.3 129.7 131.2 13.8 151.5 82.0 98.6 170.9 155.9 46.7 50.4 50.7 58.0 48.6 51.8 49.4 48.3 51.0 49.8 48.9 57.2 135.7 54.5 91.2 9.8 136.3 368.5 244.7 187.4 224.8 56.2 151.9 165.7 37.3 118.7 161.3 130.6 18.8 232.0 163.1 123.4 193.7 235.8 530.6 127.1 218.4 154.2 93.3 552.1 12.8 249.1 321.7 139.5 112.7 142.2 170.9 103.7 107.8 197.5 208.6 33.7 13.0 159.0 99.7 124.2 127.8 238.9 132.0 126.2 129.9 6.5 155.4 117.1 178.2 10.6 14.8 269.3 100.8 126.7 163.5 360.7 118.6 264.7 103.6 48.8 144.7 188.1 191.7 344.6 110.9 295.2 362.7 193.5 176.2 132.2 254.1 242.7 PABPC1 "PAB1, PABP1, PABPC2, PABPL1" ENSG00000070756 "Poly(A) binding protein cytoplasmic 1" P11940 8 100685816-100722809 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Nonsense-mediated mRNA decay" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011536, HPA045423, HPA067156" Supported Supported Cytosol NA NA 3900000 "Cluster 39: Non-specific - mRNA processing" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 32: Non-specific - Translation" Cytosol "CAB011536: AB_777008, HPA045423: AB_2679320, HPA067156: AB_2685793" "unprognostic (5.00e-2)" "unprognostic (2.64e-2)" "unprognostic (3.18e-1)" "unprognostic (4.50e-1)" "prognostic favorable (2.51e-4)" "unprognostic (1.93e-2)" "prognostic unfavorable (5.80e-4)" "unprognostic (2.51e-3)" "unprognostic (5.70e-2)" "unprognostic (1.50e-2)" "unprognostic (3.21e-3)" "unprognostic (7.24e-2)" "prognostic unfavorable (5.70e-12)" "unprognostic (6.22e-2)" "unprognostic (2.55e-1)" "unprognostic (6.98e-3)" "unprognostic (1.40e-2)" 627.6 341.5 48.8 490.8 73.4 364.0 575.7 54.9 58.6 700.3 86.2 524.3 450.2 453.5 68.3 1353.3 437.0 227.1 233.8 35.3 80.2 296.4 347.7 490.3 542.4 104.1 58.7 724.0 728.0 126.7 167.7 214.5 92.2 473.9 270.3 80.2 1287.6 172.7 197.7 732.4 502.0 226.5 64.1 483.1 524.7 507.9 92.7 421.0 303.4 75.8 532.3 630.5 853.3 81.6 2069.1 644.4 372.2 842.0 585.0 1050.0 793.4 504.4 593.5 451.8 468.7 791.5 1107.8 3230.4 1609.1 809.5 291.3 792.4 554.6 1092.3 459.5 758.2 555.4 1713.1 302.2 562.6 835.7 673.3 891.0 1338.6 1050.2 554.8 2126.1 950.7 690.8 1071.8 1339.4 1120.1 477.5 857.3 2617.8 949.5 882.3 1487.3 929.6 967.5 541.7 1074.2 301.8 953.1 629.2 650.1 415.8 548.6 1200.7 513.2 1031.7 949.5 1005.1 512.4 809.4 723.9 897.9 753.6 606.1 1523.2 609.7 1378.1 538.8 122.8 401.3 131.2 159.3 405.2 348.9 297.4 333.0 264.3 421.4 263.0 437.4 370.4 112.5 306.9 468.5 277.2 301.5 568.0 48.8 73.4 54.9 58.6 35.3 80.2 104.1 58.7 92.2 64.1 92.7 81.6 348.4 371.8 939.1 28.7 1089.1 787.4 1075.3 735.0 1067.7 66.5 1036.1 641.2 139.7 459.0 1020.8 110.3 50.1 454.2 872.8 457.0 264.1 467.0 1727.8 352.1 628.4 523.0 477.1 999.1 42.4 769.0 860.8 458.8 530.1 436.1 1054.1 357.3 570.8 308.3 615.5 72.3 34.1 853.8 360.1 1520.8 1162.9 306.0 498.9 1144.3 370.0 53.4 1583.7 167.7 679.7 29.7 41.1 626.9 698.0 424.3 674.4 655.3 446.1 388.4 473.5 88.4 499.6 530.4 876.7 1433.1 476.0 929.6 765.3 777.9 1041.1 408.3 1061.2 1296.9 PABPC3 "PABP3, PABPL3, tPABP" ENSG00000151846 "Poly(A) binding protein cytoplasmic 3" Q9H361 13 25096136-25099254 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 42 "testis: 36.8" "Group enriched" "Detected in many" 14 "Early spermatids: 217.6;Late spermatids: 135.4;Spermatocytes: 190.8" "Cancer enhanced" "Detected in some" "stomach cancer: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 15 "U-266/84: 6.8" "HPA045423, HPA067156" Approved Approved Cytosol NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA045423: AB_2679320, HPA067156: AB_2685793" "unprognostic (2.17e-2)" "unprognostic (6.50e-2)" "unprognostic (3.27e-2)" "unprognostic (2.13e-1)" "unprognostic (1.78e-1)" "unprognostic (2.98e-1)" "unprognostic (8.76e-3)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (8.00e-4)" "unprognostic (5.26e-4)" "unprognostic (1.04e-1)" "unprognostic (1.17e-2)" "unprognostic (5.18e-2)" "unprognostic (5.32e-2)" "unprognostic (1.39e-1)" "unprognostic (7.61e-3)" 0.4 0.2 0.2 0.0 0.2 0.0 0.4 0.2 0.2 0.4 0.0 0.3 0.0 0.3 0.0 0.8 0.2 0.0 0.1 0.2 0.2 0.1 0.2 0.4 0.0 0.2 0.2 0.5 0.4 0.0 0.1 0.0 0.2 0.3 0.0 0.1 0.6 0.0 0.1 0.5 0.3 0.0 0.2 0.2 0.3 36.8 0.3 0.0 0.2 0.0 0.0 0.3 0.6 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.4 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.4 0.1 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.2 6.8 0.1 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.4 0.3 0.3 0.3 0.2 0.4 0.2 0.4 0.4 0.1 0.3 0.4 0.2 0.3 0.5 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.3 0.2 0.1 0.0 0.0 0.0 1.3 11.7 9.9 2.8 0.0 0.1 0.4 0.0 5.3 0.0 1.3 0.0 0.0 2.0 4.0 0.9 0.0 0.3 217.6 0.2 0.4 2.5 4.2 2.7 0.0 0.4 1.8 2.0 0.0 0.1 4.5 0.1 2.5 1.0 1.6 1.7 0.0 1.6 2.0 5.7 12.7 135.4 3.1 1.9 5.4 0.0 2.1 1.3 0.0 0.0 0.0 0.1 3.0 4.9 0.0 4.5 0.5 2.0 1.0 0.0 6.6 4.8 10.5 190.8 5.1 0.0 12.9 2.9 2.5 0.2 2.7 5.0 PABPC4 "APP-1, iPABP" ENSG00000090621 "Poly(A) binding protein cytoplasmic 4" Q13310 1 39560709-39576790 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 469.7;skeletal muscle: 557.5" "Cell type enhanced" "Detected in all" "Kupffer cells: 460.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027301, HPA056496" Supported Enhanced Cytosol NA NA 850000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" Cytosol "HPA027301: AB_2672208, HPA056496: AB_2683153" "unprognostic (6.81e-2)" "unprognostic (7.01e-3)" "unprognostic (2.93e-2)" "unprognostic (5.45e-2)" "unprognostic (3.63e-1)" "unprognostic (1.29e-2)" "prognostic unfavorable (1.14e-7)" "unprognostic (2.22e-1)" "unprognostic (2.62e-1)" "unprognostic (1.12e-1)" "unprognostic (2.76e-2)" "unprognostic (5.71e-2)" "prognostic unfavorable (3.00e-10)" "unprognostic (1.87e-1)" "unprognostic (3.18e-1)" "unprognostic (2.91e-1)" "unprognostic (5.08e-1)" 98.4 95.9 26.1 51.2 27.5 76.8 76.1 24.7 28.6 68.8 31.5 83.6 36.8 87.2 41.1 72.1 67.8 39.8 151.9 25.8 24.4 57.0 82.0 72.9 65.1 33.6 25.6 124.8 469.7 27.9 37.4 49.6 30.4 59.3 32.7 22.7 75.5 36.9 557.5 65.0 66.7 46.2 30.4 71.2 153.1 99.4 32.7 32.7 55.0 244.6 65.1 91.9 69.2 36.1 280.8 90.3 75.7 143.3 223.0 441.9 250.7 161.6 135.2 143.5 103.6 175.0 142.2 239.7 150.3 238.5 58.0 131.5 161.2 197.8 175.8 120.6 128.7 200.2 94.1 194.7 234.5 146.5 122.5 392.7 234.3 164.0 252.6 180.0 179.4 174.9 211.3 126.6 231.5 131.5 135.3 132.8 268.9 95.4 98.0 105.4 274.6 194.9 138.4 343.0 63.9 106.9 118.3 106.1 266.1 137.3 115.8 388.9 146.2 118.6 161.8 308.1 201.3 315.1 423.3 202.5 181.7 130.8 78.6 9.8 18.2 4.8 14.2 22.9 13.3 16.0 20.6 13.0 19.0 19.9 25.3 17.6 1.9 11.8 33.0 18.2 14.9 7.9 26.1 27.5 24.7 28.6 25.8 24.4 33.6 25.6 30.4 30.4 32.7 36.1 55.0 19.2 48.9 8.8 120.6 55.8 80.7 36.5 45.5 25.9 104.4 77.5 145.3 90.1 47.7 47.8 81.3 85.2 82.0 115.5 41.1 44.4 70.7 49.0 95.7 50.5 59.3 75.3 9.4 92.3 154.1 69.1 88.7 78.9 53.2 83.0 69.9 152.7 100.5 33.7 10.3 87.5 26.4 460.9 104.6 25.6 69.0 162.4 56.9 13.1 78.6 29.1 30.9 6.0 13.7 57.0 83.2 46.3 212.5 103.5 96.4 46.5 17.5 110.5 6.6 85.3 75.2 37.4 186.3 77.5 41.8 107.1 66.7 86.2 81.7 114.9 PAICS "ADE2H1, AIRC, PAIS" ENSG00000128050 "Phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase" P22234 4 56435741-56464578 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" "Decarboxylase, Ligase, Lyase, Multifunctional enzyme" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 157.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035895, HPA041538" Approved Approved Cytosol Yes No 490000 "Cluster 30: Non-specific - Translation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA035895: AB_10669660, HPA041538: AB_2677540" "unprognostic (2.59e-3)" "unprognostic (7.90e-3)" "unprognostic (3.84e-3)" "unprognostic (2.88e-2)" "unprognostic (9.85e-2)" "unprognostic (2.82e-3)" "prognostic unfavorable (1.50e-4)" "unprognostic (8.07e-3)" "unprognostic (1.23e-2)" "prognostic favorable (8.44e-4)" "unprognostic (1.48e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (5.85e-5)" "unprognostic (7.11e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (2.41e-4)" "unprognostic (2.16e-1)" 24.5 40.2 22.7 40.1 26.7 46.8 54.6 28.3 25.0 29.3 21.6 42.8 32.1 29.7 22.1 36.3 35.4 17.8 19.7 20.3 27.8 42.7 109.7 14.1 51.3 26.0 30.1 30.7 21.7 39.5 17.7 45.9 26.1 31.0 54.7 30.4 26.4 25.8 32.4 37.6 30.8 35.7 25.6 18.3 20.7 29.5 26.8 56.4 32.4 24.1 64.5 37.4 25.4 27.2 239.3 175.3 354.3 220.6 74.3 166.1 304.0 201.7 145.1 282.5 276.0 280.5 275.7 548.0 228.3 136.0 154.1 143.6 565.5 293.0 480.8 110.4 198.8 298.7 259.5 313.4 141.8 537.1 127.6 141.9 207.9 301.0 225.0 155.7 235.4 308.6 524.7 198.5 246.8 159.3 621.5 267.2 407.5 454.8 216.5 496.2 151.7 361.5 268.4 164.5 378.8 226.4 198.6 273.7 124.3 287.2 181.2 169.8 127.7 222.6 290.1 221.8 419.0 139.1 128.2 571.1 234.8 385.2 251.0 6.0 5.2 0.4 5.2 8.7 15.0 17.8 14.4 9.2 15.3 11.0 17.4 15.5 1.1 15.9 6.9 17.0 11.2 8.7 22.7 26.7 28.3 25.0 20.3 27.8 26.0 30.1 26.1 25.6 26.8 27.2 16.4 22.4 22.9 17.0 35.7 56.6 71.9 66.0 54.1 27.4 35.8 37.5 23.3 50.1 32.3 33.1 6.2 134.4 15.3 20.5 37.2 45.0 69.4 15.2 49.1 25.1 24.7 80.8 9.1 26.3 157.5 34.2 15.3 23.3 21.0 69.1 13.2 78.7 51.5 28.6 14.6 41.0 34.6 16.1 17.2 10.6 29.8 16.1 17.8 6.5 20.2 14.0 6.2 13.0 12.2 27.4 18.6 23.3 48.1 81.7 15.9 47.7 17.9 24.6 0.0 31.3 29.2 40.0 50.3 53.1 50.4 54.6 16.8 66.4 69.7 48.9 PAIP2B KIAA1155 ENSG00000124374 "Poly(A) binding protein interacting protein 2B" Q9ULR5 2 71182738-71227103 "Predicted intracellular proteins" "Translation regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 181.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 86.0;Early spermatids: 95.1;Hepatocytes: 67.1;Proximal tubular cells: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPMI-8226: 15.8;SCLC-21H: 23.1" "Low region specificity" "Detected in all" "HPA046784, HPA072371" Approved Approved Cytosol NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol "HPA046784: AB_2679804, HPA072371: AB_2686514" "unprognostic (8.70e-2)" "unprognostic (8.20e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (8.17e-5)" "unprognostic (4.56e-2)" "unprognostic (1.34e-1)" "unprognostic (9.67e-3)" "unprognostic (1.51e-2)" "unprognostic (3.61e-1)" "unprognostic (1.78e-1)" "unprognostic (5.25e-2)" "unprognostic (2.76e-1)" "prognostic favorable (6.96e-12)" "unprognostic (1.63e-2)" "unprognostic (3.87e-1)" "unprognostic (1.21e-2)" "unprognostic (4.61e-2)" 2.4 1.6 131.5 1.8 159.1 1.3 4.5 108.3 176.8 3.1 66.3 3.8 3.7 2.9 1.8 6.1 7.2 1.1 23.0 94.7 116.5 10.3 18.1 2.7 2.1 134.9 136.6 11.5 54.2 6.0 2.2 0.6 143.0 4.8 3.7 27.7 37.9 3.5 48.5 16.4 2.7 1.7 132.8 2.2 10.5 2.2 130.3 2.4 11.6 26.7 4.6 2.8 4.0 181.5 2.5 0.6 1.0 3.6 0.4 0.5 4.4 0.3 0.1 0.3 0.2 0.9 1.0 3.2 0.6 0.0 2.4 2.0 6.1 3.7 1.2 1.7 5.0 3.1 0.4 0.1 1.6 0.8 0.2 0.6 3.3 0.2 3.6 0.9 0.6 7.2 5.5 3.0 0.2 3.2 1.0 1.7 2.6 5.8 2.3 0.0 10.5 15.8 1.9 1.7 23.1 1.3 2.6 1.7 1.1 5.5 7.5 0.2 0.1 0.3 1.9 1.9 1.0 6.1 5.5 3.9 0.2 1.1 0.5 0.5 0.3 0.5 1.0 0.4 1.2 2.5 1.3 1.0 0.4 2.6 2.1 1.9 0.2 0.8 0.4 2.3 0.6 0.6 131.5 159.1 108.3 176.8 94.7 116.5 134.9 136.6 143.0 132.8 130.3 181.5 3.3 3.2 4.5 5.2 9.9 7.8 7.0 4.0 5.7 11.3 14.8 8.8 86.0 12.8 2.7 7.3 6.2 3.2 13.2 2.7 21.5 4.9 95.1 18.4 3.9 3.9 41.5 15.6 4.2 41.3 9.2 4.7 11.2 17.5 1.3 7.5 7.1 67.1 1.9 6.7 4.6 6.3 14.2 3.2 1.6 30.0 5.3 2.6 14.2 2.8 2.4 12.3 4.1 2.5 31.9 10.4 4.0 5.3 29.9 9.4 1.3 56.9 15.5 43.3 0.0 9.3 4.0 32.9 7.7 17.3 20.0 6.3 4.7 4.3 8.1 6.0 PANK2 "C20orf48, FLJ11729, HARP, HSS, NBIA1, PKAN" ENSG00000125779 "Pantothenate kinase 2" Q9BZ23 20 3888839-3929887 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Coenzyme A biosynthesis" "Kinase, Transferase" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008440 Approved Supported Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA008440: AB_1079559" "unprognostic (4.50e-2)" "unprognostic (7.96e-3)" "unprognostic (2.26e-1)" "unprognostic (1.39e-2)" "unprognostic (1.68e-1)" "unprognostic (6.00e-2)" "prognostic unfavorable (1.20e-5)" "unprognostic (2.75e-1)" "unprognostic (3.39e-1)" "unprognostic (2.52e-1)" "unprognostic (3.02e-2)" "unprognostic (1.65e-1)" "unprognostic (6.01e-3)" "unprognostic (1.73e-2)" "unprognostic (2.18e-3)" "unprognostic (2.63e-1)" "unprognostic (1.81e-1)" 13.0 12.3 14.5 16.8 13.7 20.9 12.2 15.3 15.9 11.9 14.1 11.4 8.4 11.0 11.3 20.0 16.3 12.1 8.7 15.5 13.5 15.7 18.3 14.1 18.5 12.7 14.1 12.9 10.3 10.9 8.9 15.3 13.3 12.0 14.2 10.3 11.9 10.7 9.6 11.7 11.6 13.7 12.7 14.9 9.1 25.9 13.9 16.8 15.4 11.2 22.0 15.6 9.9 12.4 39.3 29.4 33.7 18.6 39.3 32.6 15.0 25.6 34.2 38.3 48.3 40.8 25.4 34.6 10.6 34.9 70.2 34.9 34.7 57.3 49.3 8.8 9.8 47.4 22.7 80.2 33.3 33.6 15.9 28.7 26.4 39.7 28.7 17.0 36.0 23.3 34.7 30.5 42.5 11.7 30.0 30.3 28.8 22.9 19.5 20.3 46.0 22.4 26.2 45.7 36.2 16.7 30.0 44.3 78.1 32.6 23.6 28.1 24.6 47.7 17.8 60.7 43.3 14.0 50.8 23.3 15.0 30.7 34.2 3.0 10.5 3.4 3.6 11.1 3.5 3.8 3.7 3.4 8.5 4.5 4.1 3.4 5.9 6.8 9.4 3.0 5.9 4.0 14.5 13.7 15.3 15.9 15.5 13.5 12.7 14.1 13.3 12.7 13.9 12.4 23.8 19.2 11.7 23.8 29.2 25.5 17.5 12.0 41.5 22.0 15.8 17.3 9.8 7.2 13.4 14.7 25.0 29.4 38.6 14.4 23.5 19.4 83.1 24.1 20.6 26.7 20.3 42.7 28.6 17.8 36.0 21.1 24.5 24.1 7.6 20.1 26.0 14.0 33.8 35.3 25.3 12.7 10.2 52.8 37.9 17.3 21.1 34.3 19.6 29.0 55.0 14.1 35.0 23.1 17.7 15.9 12.8 22.6 33.2 20.9 15.1 20.6 20.2 21.1 6.6 14.1 23.1 54.6 25.9 37.7 24.3 18.6 31.6 21.2 15.0 20.0 PANK4 FLJ10782 ENSG00000157881 "Pantothenate kinase 4 (inactive)" Q9NVE7 1 2508537-2526597 "Metabolic proteins, Predicted intracellular proteins" "Coenzyme A biosynthesis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011723, HPA012036, HPA027961" Uncertain Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA011723: AB_2668522, HPA012036: AB_1854952, HPA027961: AB_10602042" "unprognostic (1.23e-1)" "unprognostic (2.31e-1)" "unprognostic (3.36e-1)" "unprognostic (1.13e-1)" "unprognostic (4.92e-3)" "unprognostic (1.99e-1)" "unprognostic (1.34e-1)" "unprognostic (2.55e-1)" "unprognostic (6.51e-2)" "unprognostic (1.80e-1)" "unprognostic (1.18e-2)" "unprognostic (3.29e-2)" "prognostic favorable (1.57e-5)" "unprognostic (1.22e-1)" "unprognostic (2.03e-1)" "unprognostic (2.25e-1)" "unprognostic (8.15e-2)" 10.1 11.0 1.0 2.7 1.7 4.7 9.7 1.0 5.1 10.9 2.1 13.9 4.1 11.4 0.0 9.1 10.0 0.0 21.8 1.3 1.0 11.0 12.7 11.9 2.7 1.1 1.4 9.4 8.7 1.2 13.6 2.5 1.2 10.3 2.7 5.6 10.0 1.7 32.8 12.6 11.6 1.8 1.2 13.7 11.5 8.9 1.3 2.8 11.5 20.5 2.6 12.5 10.4 1.2 2.2 6.3 4.9 13.8 9.4 5.2 4.5 0.0 1.7 0.1 2.2 12.6 18.5 2.2 0.7 4.3 8.1 4.6 0.2 7.8 5.5 0.0 12.3 7.4 1.6 5.7 0.7 5.7 0.1 8.0 7.0 11.6 2.3 0.6 5.6 2.7 0.1 14.9 0.7 5.5 11.8 7.7 0.0 3.1 12.5 13.4 0.7 5.3 0.0 3.8 10.8 6.1 0.5 10.7 11.9 3.2 5.4 0.0 1.1 15.1 2.3 5.0 5.7 4.6 0.3 4.7 6.9 7.3 3.6 0.5 0.0 1.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.5 0.0 0.2 0.0 0.0 1.0 1.7 1.0 5.1 1.3 1.0 1.1 1.4 1.2 1.2 1.3 1.2 4.7 6.4 5.1 7.5 6.1 4.1 5.6 7.4 6.2 7.2 3.7 2.4 23.3 2.8 6.4 3.7 10.4 7.8 5.9 7.9 7.9 5.7 1.4 3.8 4.2 5.4 3.0 11.6 6.1 6.9 5.0 6.4 4.6 5.0 1.3 5.3 3.6 7.9 5.3 3.3 6.4 4.5 6.1 5.0 3.0 0.6 5.9 5.0 5.4 1.9 7.4 4.6 11.3 5.5 3.5 5.3 8.8 9.1 7.1 4.0 4.7 4.8 3.1 13.9 19.7 2.6 6.3 6.3 6.1 3.9 4.4 9.7 8.9 3.2 5.9 4.2 PAQR7 "MPRA, mSR" ENSG00000182749 "Progestin and adipoQ receptor family member 7" Q86WK9 1 25861484-25875708 "Predicted membrane proteins" "Differentiation, Oogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Late spermatids: 1939.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 75.5;HaCaT: 62.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046936 Approved Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA046936: AB_2679869" "unprognostic (1.12e-1)" "unprognostic (2.08e-2)" "unprognostic (8.03e-2)" "unprognostic (4.54e-3)" "unprognostic (1.32e-1)" "unprognostic (3.41e-1)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.47e-1)" "unprognostic (4.59e-3)" "unprognostic (7.79e-2)" "unprognostic (1.29e-1)" "unprognostic (1.31e-1)" "prognostic favorable (1.05e-5)" "unprognostic (1.60e-2)" "unprognostic (2.98e-2)" "unprognostic (1.15e-2)" "unprognostic (1.54e-2)" 5.5 23.9 8.5 4.4 8.4 5.1 5.2 7.5 8.6 11.9 10.0 6.4 20.9 11.1 28.2 17.7 20.0 7.8 3.3 7.9 10.1 35.3 7.4 5.6 4.3 9.6 10.2 35.3 6.6 13.7 6.7 21.4 9.4 7.9 2.9 1.5 5.3 24.3 3.0 31.4 18.9 9.5 9.2 10.2 8.1 46.2 10.6 3.5 5.1 1.9 4.9 13.6 13.5 9.4 30.7 6.0 5.8 18.9 7.1 14.8 20.4 19.9 17.5 19.2 17.0 9.8 75.5 0.3 13.6 19.2 6.3 62.6 3.2 33.0 11.4 12.1 3.4 25.6 8.4 12.1 12.0 0.4 3.1 14.9 43.3 13.7 10.2 16.9 7.5 2.8 2.8 2.1 14.4 7.0 0.2 1.9 9.3 3.1 10.3 2.1 0.6 3.8 39.3 22.9 3.1 11.5 32.1 40.7 14.8 7.9 11.6 4.6 8.1 3.1 9.7 10.2 5.4 0.4 0.4 1.3 14.5 0.7 6.6 5.4 7.3 15.7 1.4 13.9 1.4 4.0 0.8 1.0 7.6 1.7 1.3 1.9 3.7 3.4 17.5 0.8 0.2 1.4 8.5 8.4 7.5 8.6 7.9 10.1 9.6 10.2 9.4 9.2 10.6 9.4 4.9 0.0 3.1 11.4 2.2 18.1 4.3 4.6 4.6 2.1 9.4 9.5 1.9 17.2 5.1 77.3 0.0 52.8 1.3 0.7 21.5 5.6 350.9 23.4 11.5 5.9 4.8 0.0 11.9 13.9 12.3 7.8 0.5 9.0 7.0 4.6 10.4 5.5 11.0 3.3 11.2 2.2 0.0 10.3 14.9 1939.3 19.9 7.8 21.4 7.5 7.6 1.6 0.0 8.5 4.0 6.4 3.0 15.1 0.7 3.1 27.9 70.2 8.6 0.6 13.1 4.3 4.7 11.6 10.0 4.7 13.1 35.7 1.6 5.8 3.7 3.1 PARD6B PAR-6B ENSG00000124171 "Par-6 family cell polarity regulator beta" Q9BYG5 20 50731580-50756795 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 16.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 189.1;Glandular and luminal cells: 179.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 29.0;MCF7: 51.7;T-47d: 48.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013376 Uncertain Supported Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 44: Endometrium - Transcription" Cytosol "HPA013376: AB_1854972" "unprognostic (1.13e-1)" "unprognostic (1.31e-1)" "unprognostic (1.50e-1)" "unprognostic (1.39e-3)" "unprognostic (2.56e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (1.02e-5)" "unprognostic (2.12e-1)" "unprognostic (1.37e-1)" "unprognostic (9.33e-2)" "prognostic unfavorable (8.38e-4)" "unprognostic (2.27e-1)" "prognostic favorable (6.38e-5)" "unprognostic (1.84e-2)" "unprognostic (1.97e-1)" "unprognostic (4.18e-2)" "unprognostic (1.07e-2)" 1.9 1.1 1.6 0.8 2.0 2.3 3.5 3.7 1.8 1.7 8.4 2.5 3.6 1.4 8.2 3.1 3.8 2.5 0.8 2.7 1.8 16.1 4.4 5.4 1.0 1.8 2.1 1.1 4.6 4.3 1.4 3.9 1.6 1.2 2.3 8.9 1.8 1.7 3.9 2.9 3.2 0.8 1.8 1.1 5.7 2.7 2.0 0.9 3.7 0.9 2.1 1.7 1.5 2.4 5.4 6.2 1.7 3.7 1.1 0.4 8.0 0.4 0.6 0.9 0.7 29.0 12.7 2.4 5.4 0.1 3.8 4.3 2.6 3.9 1.5 1.2 1.5 1.3 2.1 11.5 1.2 0.9 1.3 0.1 1.9 0.5 1.6 1.7 0.1 2.3 3.1 1.6 0.1 51.7 2.5 2.3 3.0 9.0 2.3 1.4 1.7 2.3 12.9 5.9 1.1 1.6 4.1 9.6 3.0 7.2 48.8 1.3 0.2 0.5 3.2 0.5 1.0 1.9 1.3 2.0 1.3 0.9 1.1 1.6 0.2 1.5 1.4 0.3 1.5 1.1 1.4 1.4 0.3 1.3 2.2 1.4 1.1 1.6 0.6 1.3 0.9 0.4 1.6 2.0 3.7 1.8 2.7 1.8 1.8 2.1 1.6 1.8 2.0 2.4 0.4 189.1 50.4 2.9 4.5 63.0 58.9 17.0 30.7 14.4 60.3 15.0 4.3 37.1 31.1 90.1 54.2 35.5 4.0 68.6 41.1 26.2 4.0 110.1 14.4 1.7 14.9 0.4 11.5 24.4 15.0 4.7 55.5 179.2 1.3 1.8 1.8 20.1 3.7 5.0 10.6 26.7 22.4 0.8 4.2 2.5 1.8 3.5 16.0 1.9 1.2 12.3 2.1 1.5 4.6 57.5 39.7 0.7 6.3 43.6 29.3 102.0 30.0 62.7 6.6 1.2 4.8 16.6 9.4 34.7 68.3 48.4 6.3 1.5 27.3 102.7 PARP14 "ARTD8, KIAA1268, pART8" ENSG00000173193 "Poly(ADP-ribose) polymerase family member 14" Q460N5 3 122680839-122730840 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 246.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 74.7;BJ hTERT+ SV40 Large T+ RasG12V: 113.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA008846, HPA012063" Supported Supported Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 44: Endometrium - Transcription" Cytosol "HPA008846: AB_1854982, HPA012063: AB_1854981" "unprognostic (4.38e-2)" "unprognostic (1.07e-2)" "unprognostic (1.25e-1)" "unprognostic (1.95e-2)" "unprognostic (2.56e-1)" "unprognostic (2.50e-3)" "unprognostic (1.87e-1)" "unprognostic (1.33e-1)" "unprognostic (1.44e-1)" "unprognostic (4.20e-2)" "unprognostic (1.74e-3)" "unprognostic (1.62e-2)" "prognostic unfavorable (1.79e-4)" "unprognostic (7.87e-2)" "unprognostic (3.82e-2)" "unprognostic (1.58e-3)" "unprognostic (1.71e-2)" 14.0 12.6 4.3 24.3 5.1 20.1 11.3 3.6 2.7 11.4 5.5 11.5 15.3 8.2 2.4 9.0 10.7 15.2 11.1 2.8 5.1 14.9 24.5 33.5 24.0 15.1 5.9 9.2 7.8 7.3 7.6 17.8 8.6 13.0 8.7 1.1 11.7 7.2 5.0 5.3 17.5 10.2 10.9 37.4 11.7 2.2 8.9 15.4 14.7 8.3 26.8 13.7 9.4 7.8 15.6 13.0 8.0 8.3 9.1 26.2 0.0 6.1 40.1 74.7 113.1 6.9 28.7 0.0 24.2 13.4 41.8 11.5 11.9 11.6 15.0 24.0 1.5 14.6 5.8 8.7 20.4 6.4 6.8 14.7 4.7 13.0 4.8 16.4 32.2 12.3 7.0 22.7 2.1 7.9 24.8 1.5 1.1 2.1 11.1 34.2 8.3 4.3 9.5 16.2 0.6 0.0 15.3 3.1 14.1 0.8 5.7 9.3 22.0 4.0 9.4 2.3 5.5 8.7 1.6 2.7 12.0 13.8 7.2 13.1 10.8 5.8 8.6 13.7 7.2 12.8 4.5 5.6 5.6 20.3 3.6 4.1 29.5 9.5 14.7 0.7 9.9 4.3 4.3 5.1 3.6 2.7 2.8 5.1 15.1 5.9 8.6 10.9 8.9 7.8 111.5 246.8 98.4 17.3 115.3 16.8 17.0 35.9 13.1 2.1 19.6 15.6 14.6 24.3 65.9 25.8 4.2 14.1 64.9 43.0 3.9 36.0 0.3 118.8 59.8 94.7 10.7 18.5 0.5 41.2 28.4 37.2 24.5 149.8 32.2 69.6 67.1 32.5 36.5 0.0 3.0 18.2 26.4 61.6 39.9 2.1 28.0 83.9 16.0 124.6 132.2 15.1 58.7 47.3 1.1 44.0 20.2 17.3 50.9 31.8 29.5 11.5 73.0 1.0 13.1 32.7 30.3 1.9 1.1 13.7 10.5 4.8 51.4 42.8 16.0 25.9 PARVB CGI-56 ENSG00000188677 "Parvin beta" Q9HBI1 22 43999211-44172939 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 195.9;tongue: 170.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 113.2;Hofbauer cells: 90.6;Macrophages: 78.7" "Cancer enhanced" "Detected in all" "melanoma: 20.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 158.0;RPMI-8226: 159.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062601, HPA072217" Enhanced Approved Cytosol NA NA 24000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA062601: AB_2684803, HPA072217: " "unprognostic (2.41e-1)" "unprognostic (5.52e-3)" "unprognostic (1.66e-1)" "unprognostic (3.83e-2)" "unprognostic (2.10e-3)" "unprognostic (7.65e-3)" "unprognostic (1.28e-1)" "unprognostic (1.73e-2)" "unprognostic (2.28e-1)" "unprognostic (6.46e-2)" "unprognostic (1.03e-2)" "unprognostic (6.45e-2)" "unprognostic (1.28e-2)" "unprognostic (4.87e-3)" "unprognostic (3.19e-2)" "unprognostic (4.19e-2)" "unprognostic (7.05e-3)" 42.6 30.7 26.7 21.3 19.4 43.4 33.0 18.7 24.3 21.8 22.6 21.8 7.4 22.2 13.5 11.9 19.2 10.7 86.9 34.1 24.7 23.0 14.4 29.7 19.2 23.3 25.7 27.1 11.9 18.5 24.3 21.4 26.9 17.0 8.6 10.5 11.4 13.7 195.9 14.2 18.6 22.9 20.8 35.3 15.0 6.6 28.3 9.4 12.8 170.6 16.1 23.9 16.7 19.7 23.5 27.7 0.4 19.1 28.1 35.5 0.1 32.4 20.1 20.9 15.6 28.9 13.8 0.2 17.5 87.2 16.4 0.9 45.9 2.1 11.5 33.1 28.5 100.4 45.8 0.2 46.5 76.5 86.7 55.4 24.0 15.2 0.2 15.0 158.0 0.4 36.6 67.0 22.9 15.9 0.4 50.4 9.8 20.4 18.7 0.2 0.8 159.5 0.5 0.6 24.6 17.1 8.6 1.6 84.9 3.3 15.9 30.7 99.2 19.0 20.0 29.4 3.4 16.2 15.3 0.7 82.8 22.1 106.0 6.9 6.8 1.6 1.0 7.1 1.6 6.2 1.7 1.5 7.2 6.4 0.4 0.9 4.7 0.8 2.9 14.9 2.4 9.5 26.7 19.4 18.7 24.3 34.1 24.7 23.3 25.7 26.9 20.8 28.3 19.7 70.3 0.0 10.6 5.2 48.2 5.2 3.4 1.3 4.0 11.2 8.3 9.4 55.0 4.3 0.9 1.8 16.7 1.0 29.0 0.3 27.4 1.5 6.6 8.0 12.6 63.7 1.2 113.2 15.1 3.1 10.8 18.4 4.1 11.7 64.7 20.2 53.2 12.5 90.6 6.7 12.5 0.7 6.1 49.7 39.5 21.6 19.9 78.7 19.6 28.1 44.7 8.9 9.2 2.5 5.9 4.7 0.0 10.9 58.1 5.1 0.0 30.0 3.8 15.2 6.6 18.2 14.2 1.9 5.8 0.7 4.4 1.8 16.7 2.3 0.6 1.5 PASK "KIAA0135, PASKIN, STK37" ENSG00000115687 "PAS domain containing serine/threonine kinase" Q96RG2 2 241106099-241150264 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.8;lymphoid tissue: 22.9" "Cell type enhanced" "Detected in many" "Peritubular cells: 24.5;Theca cells: 26.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 19.8" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA016450, HPA021079" Uncertain Supported Cytosol NA Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 14: REH - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA016450: AB_1854992, HPA021079: AB_1854993" "unprognostic (1.76e-2)" "unprognostic (1.29e-2)" "unprognostic (2.84e-1)" "unprognostic (1.41e-2)" "unprognostic (1.14e-1)" "unprognostic (8.99e-6)" "unprognostic (1.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.60e-3)" "unprognostic (1.58e-2)" "unprognostic (1.02e-2)" "unprognostic (6.35e-2)" "unprognostic (7.12e-2)" "unprognostic (1.52e-3)" "unprognostic (1.68e-1)" "unprognostic (6.44e-2)" "unprognostic (4.38e-3)" 1.6 1.1 3.7 7.1 19.8 8.8 2.1 1.0 5.3 2.5 3.1 2.4 3.4 2.1 3.9 3.3 6.1 2.0 1.1 2.7 1.7 3.7 1.4 3.2 13.7 1.9 1.9 1.9 3.6 2.4 4.6 1.0 1.8 10.0 2.3 11.9 2.9 1.4 0.8 4.1 4.5 1.2 0.3 4.1 3.0 16.1 3.2 22.9 5.1 0.2 7.8 2.1 2.2 5.2 7.4 9.9 12.9 16.7 1.1 1.9 17.4 7.0 2.2 6.3 8.8 8.1 7.4 3.8 1.4 1.5 13.8 17.9 15.1 6.1 4.6 15.6 13.8 10.6 19.1 14.4 0.8 14.7 16.0 0.9 4.7 6.5 1.9 2.6 4.6 16.2 14.0 5.2 4.5 8.0 17.5 15.4 14.6 8.8 5.9 27.5 13.3 4.7 2.5 16.0 23.1 7.0 3.9 8.0 3.2 6.8 6.7 10.5 6.1 8.8 7.7 11.1 9.6 6.8 7.4 18.1 5.4 10.9 8.2 4.4 0.6 0.5 1.0 0.4 0.9 4.5 3.9 3.5 0.8 3.9 2.3 2.6 0.8 1.9 0.7 0.4 4.1 2.2 3.7 19.8 1.0 5.3 2.7 1.7 1.9 1.9 1.8 0.3 3.2 5.2 2.3 3.2 7.9 2.6 8.5 2.7 1.2 1.6 2.2 2.6 3.5 4.3 3.1 2.8 1.9 3.7 4.2 0.9 2.2 3.1 0.0 1.5 14.9 13.9 1.6 8.5 0.0 13.3 12.5 2.0 1.7 2.7 3.6 4.4 3.8 11.7 17.5 1.5 2.0 1.7 6.1 3.5 0.0 4.7 2.0 3.5 5.9 2.1 12.4 3.7 2.7 2.1 7.2 0.5 2.6 0.9 1.0 24.5 4.7 1.7 1.9 1.4 12.3 18.7 0.0 2.1 2.1 16.1 12.7 2.6 1.4 0.3 19.1 26.5 3.9 0.9 PBK "CT84, FLJ14385, Nori-3, SPK, TOPK" ENSG00000168078 "PDZ binding kinase" Q96KB5 8 27809624-27838082 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 22.8;testis: 70.3" "Group enriched" "Detected in many" 5 "Early spermatids: 364.9;Spermatocytes: 436.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 282.8" "Group enriched" "Detected in many" 4 "basal ganglia: 4.7;white matter: 13.9" "Not detected" "Not detected" "HPA005753, HPA050656" Enhanced Supported Approved Cytosol NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA005753: AB_1855018, HPA050656: AB_2681205" "unprognostic (7.17e-2)" "unprognostic (7.21e-3)" "unprognostic (1.04e-3)" "unprognostic (2.77e-2)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (8.29e-5)" "unprognostic (3.65e-3)" "unprognostic (7.38e-2)" "unprognostic (2.88e-3)" "prognostic unfavorable (6.56e-4)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.18e-12)" "unprognostic (9.61e-2)" "unprognostic (1.86e-1)" "unprognostic (8.30e-2)" "unprognostic (8.68e-2)" 1.1 0.6 0.1 6.6 0.1 9.1 2.3 0.0 0.1 1.1 0.0 8.9 8.4 1.2 0.0 6.6 0.6 0.7 0.2 0.1 0.1 0.4 1.1 0.7 12.8 0.1 0.3 0.2 0.4 0.2 0.0 5.1 0.2 0.4 10.1 0.0 0.9 0.0 0.2 4.8 8.1 2.7 0.1 1.5 3.6 70.3 0.3 22.8 0.5 0.1 12.4 1.6 2.1 0.1 282.8 94.2 94.4 57.9 8.3 15.7 36.9 129.5 63.0 133.2 112.3 33.7 51.2 156.4 43.3 51.7 150.2 76.4 87.6 44.7 145.7 35.8 48.0 35.0 64.6 49.2 0.6 25.7 54.1 4.4 36.0 62.6 32.8 24.3 68.5 75.9 54.3 100.6 160.4 34.5 87.7 29.1 15.6 80.1 80.0 54.4 126.9 41.2 51.2 44.9 36.1 53.2 48.2 56.0 75.0 26.2 58.0 37.3 40.6 85.6 207.3 111.5 141.5 15.4 39.4 70.1 54.0 43.4 188.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.3 0.2 0.1 0.3 0.1 0.2 0.0 0.0 0.0 4.2 8.9 2.8 10.8 0.0 0.0 2.9 2.4 0.5 2.8 2.6 0.0 0.0 29.8 1.3 5.5 0.0 0.6 364.9 2.5 2.2 2.4 0.0 61.7 0.1 0.0 49.3 6.7 6.6 3.5 0.0 13.5 5.7 1.7 5.0 0.0 0.1 9.4 6.1 1.9 1.6 76.8 8.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 3.0 14.0 2.0 1.5 0.3 0.1 0.0 6.6 0.1 5.8 436.4 38.1 9.4 2.4 6.7 1.9 2.4 18.7 3.8 PCBP4 "LIP4, MCG10" ENSG00000090097 "Poly(rC) binding protein 4" P57723 3 51957454-51974016 "Predicted intracellular proteins" "DNA-binding, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 391.4" "Group enriched" "Detected in many" 5 "Bipolar cells: 374.5;Cone photoreceptor cells: 654.7;Rod photoreceptor cells: 592.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 22 "B-cells: 5.2;granulocytes: 7.0;T-cells: 12.0" "Cell line enhanced" "Detected in all" "SH-SY5Y: 160.4;SK-MEL-30: 140.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057754 Supported Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 54: Non-specific - Microtubule organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "HPA057754: AB_2683517" "unprognostic (7.17e-2)" "unprognostic (8.16e-2)" "unprognostic (1.42e-1)" "unprognostic (1.34e-2)" "unprognostic (4.94e-3)" "unprognostic (1.94e-2)" "unprognostic (4.97e-3)" "unprognostic (4.46e-2)" "unprognostic (1.26e-1)" "unprognostic (1.09e-1)" "unprognostic (5.45e-2)" "unprognostic (1.62e-1)" "unprognostic (3.13e-2)" "unprognostic (6.79e-2)" "unprognostic (1.89e-1)" "unprognostic (3.59e-1)" "unprognostic (4.72e-2)" 25.7 26.9 86.3 9.2 111.6 2.6 27.7 100.8 106.8 41.6 75.1 40.2 18.3 39.3 13.4 16.0 31.9 13.0 68.4 87.7 92.1 30.1 20.0 31.2 8.3 116.1 106.6 33.8 20.1 24.1 48.7 8.6 101.9 55.5 9.3 391.4 24.7 22.1 154.1 21.7 24.1 16.8 91.3 22.3 33.3 24.4 106.5 5.7 35.0 96.3 6.5 38.2 30.4 139.9 35.1 11.8 46.3 67.8 20.6 36.6 7.9 78.7 38.1 46.4 29.8 44.2 12.4 1.1 11.5 62.6 41.0 8.1 43.4 27.5 21.7 55.4 7.0 4.4 41.3 46.1 33.2 4.5 32.7 49.8 50.6 29.6 12.9 57.5 23.5 20.1 2.2 15.2 75.3 16.5 1.9 5.4 22.5 22.2 31.5 24.5 22.4 6.2 16.5 24.7 90.3 160.4 21.5 11.6 140.2 12.2 21.5 17.0 47.2 49.3 92.6 15.7 42.8 10.1 7.0 7.2 57.2 9.9 73.5 7.0 0.1 3.8 11.1 0.0 7.8 5.2 10.6 10.9 0.3 2.6 4.8 3.7 0.0 0.1 0.0 0.1 12.0 3.4 86.3 111.6 100.8 106.8 87.7 92.1 116.1 106.6 101.9 91.3 106.5 139.9 14.9 3.2 3.2 27.7 3.8 8.7 16.2 14.2 9.1 374.5 12.4 15.7 7.3 1.5 5.6 9.2 654.7 1.5 6.3 7.7 17.6 31.4 49.8 2.2 15.8 17.3 62.0 0.4 15.0 23.4 1.2 13.0 6.6 4.2 1.3 7.8 15.7 3.6 1.1 42.1 20.8 9.4 16.2 1.0 5.1 101.2 22.4 1.5 23.2 5.6 0.9 88.8 9.2 40.7 65.0 42.3 16.6 16.1 5.3 19.8 21.2 10.7 1.5 592.7 6.6 11.6 17.9 1.4 6.0 4.4 11.8 0.5 9.6 3.6 6.1 11.1 PCDH19 "EFMR, EIEE9, KIAA1313" ENSG00000165194 "Protocadherin 19" Q8TAB3 X 100291644-100410273 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "brain: 21.5" "Cell type enhanced" "Detected in many" "Adipocytes: 29.9;Excitatory neurons: 24.5;Inhibitory neurons: 51.8;Oligodendrocyte precursor cells: 40.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 3.6;ovarian cancer: 3.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "AF22: 18.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027533 Approved Approved Cytosol NA NA 83000 "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA027533: AB_10602043" "unprognostic (7.38e-2)" "unprognostic (1.28e-1)" "unprognostic (2.92e-1)" "unprognostic (5.04e-2)" "unprognostic (2.13e-1)" "unprognostic (2.12e-1)" "unprognostic (1.96e-1)" "unprognostic (4.77e-2)" "unprognostic (3.64e-2)" "unprognostic (1.36e-2)" "unprognostic (2.53e-1)" "unprognostic (2.79e-1)" "unprognostic (9.77e-3)" "unprognostic (2.82e-3)" "unprognostic (1.53e-1)" "unprognostic (1.80e-4)" "unprognostic (1.37e-1)" 1.8 0.1 6.8 0.2 7.6 0.0 1.7 0.0 10.7 1.6 0.0 1.3 0.2 1.1 0.2 0.8 0.6 0.4 0.3 10.7 12.0 0.2 0.0 0.1 0.2 0.6 1.3 1.0 0.1 0.1 0.7 0.1 4.1 0.2 1.7 1.8 0.6 0.3 0.4 0.9 0.4 0.9 0.0 0.0 0.5 0.6 21.5 0.8 0.2 0.9 0.0 0.8 0.6 0.0 0.0 0.0 18.0 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.2 3.2 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.2 0.0 0.0 2.1 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.4 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 7.6 0.0 10.7 10.7 12.0 0.6 1.3 4.1 0.0 21.5 0.0 29.9 0.0 0.5 13.4 0.0 3.1 0.1 0.9 4.6 12.9 0.5 0.8 1.8 7.2 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 1.4 6.2 11.3 1.8 0.0 24.5 0.0 0.1 2.9 0.0 1.4 0.0 2.5 1.1 0.0 0.1 0.0 51.8 0.1 0.0 0.3 3.4 2.2 3.4 0.1 0.0 7.5 0.0 1.9 0.0 40.7 2.2 0.1 0.1 0.4 0.0 0.4 0.0 0.2 1.3 1.9 0.0 5.9 7.8 0.1 1.5 1.0 1.6 0.0 0.2 0.7 0.0 0.1 PCMT1 ENSG00000120265 "Protein-L-isoaspartate (D-aspartate) O-methyltransferase" P22061 6 149749443-149811420 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1022.2;Late spermatids: 428.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003239 Approved Supported Cytosol No No 4100000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 47: Non-specific - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "HPA003239: AB_1079580" "prognostic unfavorable (4.02e-7)" "prognostic unfavorable (9.58e-4)" "unprognostic (1.35e-2)" "prognostic unfavorable (4.27e-4)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.88e-4)" "prognostic unfavorable (2.58e-4)" "unprognostic (1.91e-2)" "unprognostic (1.58e-2)" "unprognostic (9.02e-2)" "unprognostic (6.45e-2)" "unprognostic (6.77e-2)" "unprognostic (6.14e-2)" "unprognostic (4.38e-1)" "unprognostic (1.70e-1)" "unprognostic (2.17e-2)" "prognostic unfavorable (6.38e-4)" 48.7 43.2 77.5 32.8 85.1 75.9 46.2 70.2 107.1 46.4 56.4 45.5 36.6 38.8 48.5 45.3 39.2 28.4 121.7 87.5 84.8 51.1 73.8 37.9 41.4 80.3 73.0 39.3 38.1 46.3 43.3 42.9 86.2 52.1 43.1 55.8 39.8 50.1 211.9 44.6 34.6 48.9 71.1 34.5 37.8 76.7 72.3 57.4 49.0 163.3 46.7 40.7 38.0 79.2 87.3 68.4 70.4 88.6 152.1 125.9 77.6 140.7 82.9 114.7 143.4 200.1 65.4 117.9 113.0 127.5 126.5 106.6 123.9 143.6 159.9 79.2 180.0 175.5 122.2 192.1 99.2 203.7 197.7 62.8 105.2 128.5 138.5 80.7 107.6 89.8 256.5 107.7 142.3 258.9 98.5 150.4 56.5 84.7 78.6 83.4 89.7 82.6 108.9 62.4 137.5 52.4 111.2 173.9 97.7 82.5 107.8 146.1 83.3 67.2 80.7 124.7 151.2 64.1 109.9 115.4 103.6 135.8 137.7 162.9 193.2 178.0 93.0 182.4 94.7 105.0 93.7 102.8 176.0 81.5 86.5 98.0 101.6 108.5 185.7 79.9 129.2 204.1 77.5 85.1 70.2 107.1 87.5 84.8 80.3 73.0 86.2 71.1 72.3 79.2 57.0 54.5 41.4 21.2 62.6 175.1 74.4 204.4 56.3 72.6 48.0 40.6 154.1 60.1 96.4 79.1 37.5 169.3 66.8 56.6 78.2 113.5 1022.2 51.9 58.4 69.8 55.2 170.1 77.0 110.7 214.0 79.2 26.0 48.8 107.7 38.8 53.9 115.6 119.1 65.6 52.8 72.9 187.2 78.7 127.5 428.1 71.7 78.2 138.7 31.9 143.7 121.2 74.2 30.7 72.2 106.6 57.9 73.7 71.8 67.8 65.1 89.3 106.2 66.3 111.7 64.0 110.4 224.9 96.3 60.7 157.6 148.3 83.0 55.0 58.7 59.1 PCNX3 "FLJ22427, PCNXL3" ENSG00000197136 "Pecanex 3" Q9H6A9 11 65615773-65637439 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 12.9;Endometrial ciliated cells: 13.5;Glandular and luminal cells: 20.4;Granulosa cells: 17.7;Pancreatic endocrine cells: 13.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018084 Uncertain Approved Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 64: Macrophages - Immune response" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA018084: AB_1855083" "unprognostic (9.93e-2)" "unprognostic (1.33e-1)" "unprognostic (5.46e-2)" "unprognostic (1.09e-2)" "unprognostic (2.54e-1)" "unprognostic (1.70e-2)" "unprognostic (3.13e-3)" "unprognostic (1.42e-1)" "unprognostic (1.16e-1)" "unprognostic (7.69e-3)" "unprognostic (7.06e-2)" "unprognostic (2.44e-2)" "unprognostic (8.52e-3)" "unprognostic (6.51e-3)" "unprognostic (1.93e-1)" "unprognostic (2.32e-2)" "unprognostic (4.82e-1)" 5.2 6.5 3.9 8.0 3.3 10.4 5.5 2.5 4.7 5.9 2.0 7.3 8.2 7.8 1.6 7.7 6.4 4.5 4.5 3.2 1.1 5.4 5.1 6.7 7.3 4.4 3.2 6.0 8.1 4.6 6.6 5.0 2.9 6.2 3.2 2.6 7.9 4.9 4.2 7.7 9.0 4.0 1.8 8.6 7.1 8.9 4.2 7.2 7.4 2.1 4.3 6.3 5.6 4.7 19.5 28.6 10.3 25.6 7.9 6.1 23.3 13.5 11.5 12.9 9.4 13.8 21.5 14.2 25.4 12.0 17.5 31.2 11.0 15.6 3.8 12.1 19.4 18.6 28.6 11.4 8.8 18.3 21.9 11.6 7.7 12.7 10.0 5.8 12.7 14.7 21.7 11.7 7.6 28.8 15.6 14.1 20.9 8.4 18.2 21.6 9.2 18.6 5.6 30.9 12.7 19.0 14.3 18.6 15.7 4.5 32.8 12.4 18.3 22.3 20.7 18.6 13.6 19.1 12.2 12.7 17.8 8.8 19.9 3.5 0.9 0.6 1.2 0.4 1.0 0.5 0.7 0.7 0.5 0.8 0.5 0.7 1.3 0.6 0.7 1.2 0.2 0.6 3.9 3.3 2.5 4.7 3.2 1.1 4.4 3.2 2.9 1.8 4.2 4.7 10.8 6.4 6.4 0.0 1.5 0.0 0.0 0.0 0.0 0.0 11.3 8.4 0.0 0.0 0.6 12.9 0.0 6.8 10.7 0.0 0.0 9.1 0.0 13.5 9.1 5.1 0.0 0.0 0.0 8.9 5.6 3.2 0.0 20.4 5.1 17.7 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 2.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 5.9 0.0 0.0 4.3 0.7 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 8.3 3.0 10.2 0.0 0.0 PCNX4 "C14orf135, PCNXL4" ENSG00000126773 "Pecanex 4" Q63HM2 14 60091911-60169133 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 42.8;Endometrial ciliated cells: 82.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002076, HPA003390" Uncertain Approved Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA002076: AB_1078322, HPA003390: AB_2066703" "unprognostic (2.00e-1)" "unprognostic (1.45e-1)" "unprognostic (1.89e-1)" "unprognostic (9.87e-2)" "unprognostic (2.18e-1)" "unprognostic (2.94e-1)" "unprognostic (3.83e-3)" "unprognostic (2.01e-1)" "unprognostic (1.54e-1)" "unprognostic (3.28e-1)" "unprognostic (1.40e-1)" "unprognostic (1.81e-1)" "prognostic favorable (6.84e-5)" "unprognostic (2.13e-1)" "unprognostic (2.08e-1)" "unprognostic (4.14e-2)" "unprognostic (8.59e-2)" 7.8 9.2 4.1 6.3 4.8 7.4 8.1 7.0 4.4 10.1 12.1 6.3 5.0 12.5 7.1 5.6 13.1 8.3 11.1 3.9 6.1 12.3 6.7 7.2 7.1 5.0 6.0 16.3 6.5 11.4 11.9 8.5 4.7 11.7 6.7 18.2 7.1 8.5 12.3 7.4 6.1 10.2 4.9 7.4 6.2 11.0 5.7 11.6 9.7 5.7 7.0 6.6 7.8 6.2 85.2 14.3 25.2 17.3 19.2 22.2 11.1 28.5 44.1 31.2 38.3 15.0 26.1 14.8 11.6 23.7 26.0 11.1 16.6 16.2 51.7 20.8 7.9 25.0 10.1 9.7 39.7 25.0 17.7 18.5 10.2 23.0 38.3 24.3 14.9 34.8 12.5 21.2 48.2 11.5 35.9 8.0 12.7 9.7 17.4 20.9 31.8 6.4 15.8 11.7 17.9 21.8 25.5 9.2 18.2 13.4 22.7 11.1 30.7 66.4 52.8 16.7 20.5 7.1 7.4 19.6 26.1 8.5 33.2 3.4 4.1 3.3 4.8 4.3 6.5 4.1 3.4 4.2 4.4 2.8 3.7 4.4 2.1 8.4 5.2 4.4 3.8 3.4 4.1 4.8 7.0 4.4 3.9 6.1 5.0 6.0 4.7 4.9 5.7 6.2 22.3 16.0 29.9 0.0 18.2 0.0 0.0 0.0 0.0 0.0 19.9 17.5 0.0 0.0 19.2 25.8 0.0 18.3 42.8 0.0 17.6 18.4 0.0 82.0 37.4 14.0 0.0 0.0 0.0 13.1 8.3 13.6 0.0 27.0 15.2 33.9 0.0 0.0 18.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.5 0.0 0.0 10.3 0.0 0.0 0.0 0.0 20.4 0.0 0.0 18.5 0.0 0.0 14.4 34.2 0.0 0.0 0.0 13.2 0.0 0.0 0.0 0.0 19.4 14.5 33.8 0.0 0.0 PDCD1LG2 "B7-DC, bA574F11.2, Btdc, CD273, PD-L2, PDL2" ENSG00000197646 "Programmed cell death 1 ligand 2" Q9BQ51 9 5510531-5571282 "Cancer-related genes, CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 17.9;Langerhans cells: 13.1;Microglial cells: 12.2;monocytes: 26.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 71.4;BJ hTERT+: 111.6;HDLM-2: 88.1;TIME: 49.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013411 Approved Uncertain Cytosol "Secreted - unknown location" NA NA 31000000 "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" Cytosol "HPA013411: AB_1855102" "unprognostic (3.93e-2)" "unprognostic (1.90e-1)" "unprognostic (3.51e-3)" "unprognostic (6.68e-3)" "unprognostic (7.66e-2)" "unprognostic (6.77e-2)" "unprognostic (5.72e-2)" "unprognostic (2.91e-1)" "unprognostic (1.68e-1)" "unprognostic (4.37e-3)" "unprognostic (5.79e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (1.15e-4)" "unprognostic (5.00e-2)" "unprognostic (4.66e-2)" "unprognostic (2.01e-1)" "unprognostic (7.51e-3)" 4.4 0.8 0.4 6.9 0.6 0.3 4.3 0.5 0.5 2.5 0.3 1.7 0.7 2.2 1.2 2.0 2.4 3.4 2.7 0.4 0.8 1.2 4.2 7.1 10.4 1.1 0.6 1.6 0.6 0.4 0.2 4.8 1.1 1.0 2.1 0.0 1.3 1.4 1.5 1.4 1.5 3.1 0.9 15.1 1.4 0.6 0.7 5.0 1.0 2.2 6.2 4.2 2.2 1.3 6.0 0.0 0.0 0.0 4.7 5.4 0.1 71.4 111.6 33.7 40.4 0.0 0.3 0.0 0.2 29.2 4.8 0.5 0.1 9.7 33.3 88.1 0.0 0.0 0.0 0.0 26.5 0.0 0.0 5.0 0.1 15.8 18.5 9.7 22.4 0.0 0.0 8.5 41.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.0 0.7 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.2 0.0 0.1 49.7 24.0 1.4 11.8 20.1 1.2 0.1 0.1 13.6 0.0 3.0 1.5 0.3 0.0 0.5 1.4 0.6 0.2 0.7 0.3 0.3 0.1 0.0 0.3 0.7 0.0 0.1 0.0 1.1 0.3 0.4 0.6 0.5 0.5 0.4 0.8 1.1 0.6 1.1 0.9 0.7 1.3 6.1 6.4 0.5 1.6 0.4 1.0 0.1 0.7 1.8 0.0 0.2 1.5 0.1 0.0 0.7 0.0 0.0 0.6 0.4 0.0 0.0 0.1 0.0 0.0 0.4 2.2 0.0 0.0 1.6 0.2 17.9 6.7 0.5 0.0 3.8 0.2 6.8 0.0 2.9 0.0 1.4 0.0 0.0 5.3 13.1 0.0 5.9 2.5 1.8 12.2 26.4 0.0 0.0 1.0 2.4 3.7 0.0 2.2 1.5 0.1 0.0 0.0 0.0 0.0 0.0 2.2 3.1 0.0 0.0 0.3 1.0 0.8 1.1 0.1 0.0 0.1 PDE2A ENSG00000186642 "Phosphodiesterase 2A" O00408 11 72576141-72674591 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 197.0" "Group enriched" "Detected in many" 6 "Adipocytes: 114.9;Endothelial cells: 58.5;Enteroendocrine cells: 34.4;Excitatory neurons: 70.1;Hepatic stellate cells: 118.2;Inhibitory neurons: 35.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 75.1;basal ganglia: 84.7;cerebral cortex: 102.1;hippocampal formation: 84.4;white matter: 48.3" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 2.8;T-cells: 7.3" "Cell line enriched" "Detected in some" 8 "HeLa: 513.6" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 5 "amygdala: 83.5;basal ganglia: 146.9;cerebral cortex: 90.5;hippocampal formation: 94.0" "CAB009752, HPA031192" Enhanced Supported Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB009752: AB_2268159, HPA031192: AB_2673781" "unprognostic (1.92e-1)" "unprognostic (1.52e-3)" "unprognostic (4.58e-2)" "unprognostic (1.49e-1)" "unprognostic (1.26e-1)" "unprognostic (2.50e-1)" "prognostic favorable (1.76e-6)" "unprognostic (3.06e-2)" "unprognostic (1.35e-1)" "unprognostic (3.01e-3)" "unprognostic (3.13e-3)" "unprognostic (1.50e-2)" "unprognostic (1.77e-2)" "unprognostic (2.85e-3)" "unprognostic (6.31e-2)" "unprognostic (7.72e-2)" "unprognostic (7.96e-4)" 89.2 44.1 75.1 5.1 84.7 4.7 83.6 0.0 102.1 38.1 0.0 34.6 6.0 27.2 8.3 18.6 39.3 22.7 41.1 84.4 7.0 32.5 19.4 12.6 6.7 6.4 5.1 11.6 6.9 5.5 11.8 12.0 10.1 20.7 8.9 3.0 9.2 10.7 16.8 18.1 18.7 18.5 0.0 197.0 17.1 7.4 17.9 3.8 24.1 28.9 3.5 28.8 27.1 48.3 0.3 0.2 0.7 0.2 0.2 0.1 0.3 0.1 0.2 0.2 0.4 0.4 2.5 0.8 12.2 0.2 1.9 0.2 0.9 0.1 0.1 0.1 0.1 0.0 513.6 0.8 0.9 0.0 7.8 0.1 1.1 2.7 20.5 1.1 11.3 0.5 0.8 0.9 0.1 0.0 0.2 0.2 7.4 0.2 14.0 0.0 0.2 1.4 0.1 0.3 44.5 2.4 0.4 0.2 2.2 0.7 0.3 0.1 65.2 0.1 9.4 3.5 0.4 0.4 0.2 0.1 3.9 0.1 0.6 0.0 0.6 0.0 7.3 0.8 4.2 2.8 4.3 4.3 1.0 1.8 2.7 2.3 0.1 0.0 0.4 0.0 1.8 1.5 75.1 84.7 0.0 102.1 84.4 7.0 6.4 5.1 10.1 0.0 17.9 48.3 114.9 0.0 0.5 2.0 0.7 2.5 0.1 0.0 0.0 4.9 0.6 1.0 7.8 0.0 0.0 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.6 0.0 0.1 58.5 34.4 5.3 70.1 0.0 0.3 2.1 0.0 0.1 1.3 0.1 118.2 2.1 0.5 1.7 35.6 1.2 0.0 9.4 8.2 2.5 0.3 4.9 1.8 11.2 0.0 0.0 0.0 9.0 5.7 0.1 0.0 0.4 1.5 0.1 0.0 0.1 0.0 0.4 0.0 1.8 6.6 4.8 2.5 0.5 2.8 0.0 0.6 0.2 0.1 0.3 PDE5A ENSG00000138735 "Phosphodiesterase 5A" O76074 4 119494397-119628804 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 66.1;Inhibitory neurons: 58.3;Oligodendrocyte precursor cells: 56.8;Peritubular cells: 104.9;Smooth muscle cells: 80.9" "Group enriched" "Detected in all" 4 "prostate cancer: 7.0;thyroid cancer: 27.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 47.5;HHSteC: 65.9;hTERT-RPE1: 24.6" "Region enhanced" "Detected in all" "cerebellum: 18.2" "Low region specificity" "Detected in all" "HPA004729, HPA012873" Approved Approved Cytosol NA NA 850000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA004729: AB_1079588, HPA012873: AB_1855124" "unprognostic (6.95e-2)" "prognostic favorable (5.20e-4)" "unprognostic (1.28e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-1)" "unprognostic (3.66e-2)" "unprognostic (7.36e-2)" "unprognostic (2.58e-2)" "unprognostic (2.29e-2)" "unprognostic (6.97e-2)" "unprognostic (2.05e-2)" "unprognostic (2.54e-1)" "unprognostic (2.16e-2)" "unprognostic (1.52e-2)" "unprognostic (8.98e-2)" "unprognostic (8.71e-3)" "prognostic unfavorable (1.17e-4)" 15.4 11.3 0.9 10.9 3.5 2.1 9.6 4.9 3.7 32.7 12.6 37.0 15.5 14.4 41.5 41.3 22.9 10.4 12.8 1.4 3.6 5.9 1.5 22.1 6.4 4.9 8.2 5.4 12.4 8.3 3.5 13.2 5.2 59.8 25.9 9.6 9.8 49.8 6.9 5.0 18.9 11.4 0.0 5.8 9.6 9.4 3.4 3.7 16.8 5.6 3.5 14.6 15.8 1.9 16.7 0.8 11.0 1.2 3.7 5.5 1.9 10.7 47.5 0.5 1.0 1.0 1.3 1.6 0.5 13.4 3.0 5.8 3.5 1.7 1.3 0.4 7.4 18.5 2.6 0.9 65.9 3.9 1.7 6.1 3.3 1.1 0.1 24.6 1.4 3.7 2.0 2.9 1.6 0.9 5.0 0.6 2.3 1.8 2.8 0.7 5.9 4.3 4.1 4.9 4.3 8.8 13.0 15.3 1.3 8.1 2.7 2.1 2.5 6.2 5.2 3.4 1.5 4.1 2.0 1.5 5.9 1.0 0.9 0.0 0.0 0.0 0.1 0.0 0.5 0.4 0.3 0.1 0.0 0.3 0.1 0.2 0.4 0.2 0.1 0.1 0.1 1.2 0.9 3.5 4.9 3.7 1.4 3.6 4.9 8.2 5.2 0.0 3.4 1.9 7.8 6.4 3.9 19.9 1.3 3.4 2.8 1.1 5.7 8.1 11.0 8.4 5.5 14.3 3.7 1.8 14.6 0.4 0.9 15.5 0.0 15.8 30.6 5.0 12.6 7.8 2.4 0.0 66.1 2.9 0.3 28.1 1.1 3.9 1.3 1.6 0.7 0.9 0.3 5.0 58.3 9.5 2.0 0.0 3.5 11.5 20.8 11.3 5.4 40.3 1.3 28.5 2.1 56.8 41.1 3.9 10.3 104.9 1.4 3.6 7.9 0.5 0.8 5.8 19.7 5.5 80.9 5.4 6.3 3.5 2.4 0.3 1.7 7.0 11.1 2.6 PDE6B "CSNB3, CSNBAD2, PDEB, rd1, RP40" ENSG00000133256 "Phosphodiesterase 6B" P35913 4 625573-670782 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Congenital stationary night blindness, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "retina: 385.0" "Cell type enriched" "Detected in many" 5 "Rod photoreceptor cells: 460.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "EFO-21: 11.5;JURKAT: 17.3;MOLT-4: 31.3;REH: 16.8;SCLC-21H: 20.2;SH-SY5Y: 11.9;U-266/84: 24.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA054148, HPA059929" Enhanced Approved Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 77: Retina - Visual perception" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol "HPA054148: AB_2682401, HPA059929: AB_2684166" "unprognostic (2.43e-2)" "unprognostic (1.33e-4)" "unprognostic (2.45e-4)" "unprognostic (7.18e-3)" "unprognostic (1.88e-2)" "unprognostic (5.04e-3)" "unprognostic (7.32e-3)" "prognostic favorable (5.34e-4)" "unprognostic (9.70e-2)" "unprognostic (1.14e-1)" "unprognostic (1.37e-2)" "unprognostic (2.33e-2)" "unprognostic (4.09e-2)" "unprognostic (1.67e-2)" "unprognostic (2.26e-1)" "unprognostic (2.41e-3)" "unprognostic (1.85e-1)" 1.9 2.2 13.5 5.5 25.7 8.4 4.1 8.2 22.3 2.5 1.9 1.7 1.2 2.7 4.0 1.7 10.2 3.7 5.9 11.2 22.6 4.9 1.0 4.6 14.3 22.8 19.9 2.8 1.8 8.2 4.1 3.1 25.5 2.8 1.3 385.0 3.8 3.0 1.1 2.1 3.0 2.5 9.3 10.1 2.9 4.4 24.1 12.2 12.0 0.1 9.3 3.8 1.4 39.3 0.1 0.0 1.2 0.5 0.3 0.4 0.4 0.0 0.1 0.8 2.0 0.0 0.1 0.3 11.5 0.3 0.9 0.1 2.5 0.6 0.0 0.1 0.0 1.0 0.3 0.1 5.8 0.2 0.4 0.7 0.0 3.5 0.0 0.8 1.1 17.3 0.1 1.0 0.1 0.3 31.3 0.1 9.4 0.7 0.0 16.8 0.2 0.2 2.1 1.3 20.2 11.9 0.0 0.3 0.1 4.2 0.6 0.0 0.4 0.2 1.2 0.2 0.4 7.7 24.0 0.3 0.3 0.3 0.2 16.8 5.4 0.9 14.0 7.7 12.6 12.8 9.3 9.8 8.5 21.4 14.6 15.8 1.4 14.4 8.1 18.2 15.5 9.4 13.5 25.7 8.2 22.3 11.2 22.6 22.8 19.9 25.5 9.3 24.1 39.3 0.5 3.2 5.0 4.2 6.4 0.4 2.1 1.2 2.8 20.7 3.9 2.4 4.4 0.0 3.5 0.0 83.4 0.1 8.4 0.2 1.9 6.9 0.4 7.0 2.2 2.9 1.8 7.4 40.3 0.6 0.3 1.3 1.5 2.5 3.8 5.4 2.2 0.0 11.3 11.8 27.3 0.5 4.1 5.1 1.4 0.3 1.5 3.3 3.6 4.7 6.2 31.1 7.2 10.1 33.9 0.8 0.2 1.5 7.5 1.9 0.0 8.4 11.2 460.1 0.0 1.6 1.1 4.3 11.0 1.9 0.3 0.3 5.9 3.5 0.4 1.3 PDLIM3 ALP ENSG00000154553 "PDZ and LIM domain 3" Q53GG5 4 185500660-185535507 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "skeletal muscle: 4781.7;tongue: 1519.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 228.9;Ductal cells: 332.7;Melanocytes: 124.5;Peritubular cells: 196.0;Skeletal myocytes: 428.3;Smooth muscle cells: 131.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 115.6;RH-30: 26.9;U-266/70: 111.2;U-266/84: 34.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004749 Enhanced Supported Cytosol NA NA 240000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 37: Myocytes - Muscle contraction" Cytosol "HPA004749: AB_1855150" "unprognostic (2.75e-1)" "unprognostic (3.85e-2)" "unprognostic (3.20e-2)" "unprognostic (2.49e-1)" "unprognostic (1.08e-2)" "unprognostic (1.11e-2)" "prognostic unfavorable (7.22e-4)" "unprognostic (3.15e-2)" "unprognostic (3.64e-1)" "unprognostic (1.62e-1)" "unprognostic (9.46e-2)" "unprognostic (3.77e-1)" "prognostic unfavorable (4.97e-7)" "unprognostic (1.64e-3)" "unprognostic (7.77e-2)" "prognostic unfavorable (2.13e-6)" "unprognostic (2.78e-3)" 36.3 11.5 12.7 25.7 13.3 0.0 34.5 16.8 14.8 22.7 10.9 201.2 20.8 235.3 59.1 216.2 97.5 40.1 314.0 12.0 15.7 13.9 7.7 55.2 10.7 19.9 14.2 38.1 18.7 0.8 20.7 18.8 13.8 87.0 32.5 11.2 56.3 148.1 4781.7 12.1 69.0 127.6 17.9 24.5 95.8 8.2 14.6 4.1 32.7 1519.6 26.2 141.1 40.8 14.2 0.0 0.0 0.9 0.0 0.3 0.0 0.8 0.0 0.0 0.3 1.0 1.2 0.4 0.0 0.0 0.0 6.0 0.0 0.0 0.2 0.0 0.0 15.1 0.0 0.8 4.7 13.5 0.0 0.0 8.7 0.0 2.6 0.0 12.3 9.1 0.0 0.0 0.0 115.6 0.0 0.0 0.1 2.4 0.0 1.0 0.0 26.9 0.3 0.0 0.0 17.6 13.3 0.0 0.0 7.3 2.8 0.6 0.0 7.9 0.0 7.6 0.1 7.1 111.2 34.8 0.0 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 13.3 16.8 14.8 12.0 15.7 19.9 14.2 13.8 17.9 14.6 14.2 22.4 9.6 6.0 37.2 2.6 8.9 11.4 0.7 12.5 12.1 72.8 105.7 228.9 5.7 2.2 0.0 12.5 2.5 0.6 0.2 0.0 332.7 0.4 1.4 0.8 39.0 3.5 0.0 2.5 16.7 2.7 82.9 1.1 1.1 0.0 1.3 67.5 0.9 1.6 5.0 0.5 0.5 2.0 1.8 11.7 2.6 19.6 2.3 124.5 1.0 3.2 36.4 0.0 6.6 2.6 31.2 0.0 196.0 7.3 12.2 0.0 0.2 3.2 44.3 105.2 428.3 131.4 4.0 12.6 2.4 7.1 12.2 2.5 2.4 0.3 3.9 PDPK1 PDK1 ENSG00000140992 "3-phosphoinositide dependent protein kinase 1" O15530 16 2537979-2603188 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004272, HPA035199" Supported Supported Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" Cytosol "CAB004272: AB_626657, HPA035199: AB_2674514" "unprognostic (2.67e-2)" "unprognostic (1.63e-1)" "unprognostic (3.12e-3)" "unprognostic (4.21e-2)" "unprognostic (1.34e-1)" "unprognostic (4.69e-3)" "unprognostic (8.37e-2)" "unprognostic (3.18e-2)" "unprognostic (8.17e-2)" "unprognostic (3.70e-2)" "unprognostic (1.52e-2)" "unprognostic (3.28e-2)" "prognostic favorable (1.29e-14)" "unprognostic (2.04e-2)" "unprognostic (5.96e-2)" "unprognostic (1.95e-1)" "unprognostic (2.16e-1)" 11.6 13.5 15.1 12.4 25.2 16.1 11.1 10.2 20.6 10.9 1.5 15.8 17.3 11.8 13.2 13.3 14.7 9.5 15.1 19.2 5.2 17.0 12.4 13.6 15.0 10.8 6.1 14.0 19.4 27.1 11.2 12.1 11.3 13.0 14.9 15.5 17.8 12.2 18.9 14.2 19.6 12.3 3.7 13.9 13.6 14.7 7.7 16.8 15.8 19.2 14.1 11.1 10.4 12.5 13.1 16.5 20.1 13.5 20.3 16.9 21.5 21.7 13.6 18.7 15.6 16.6 15.2 21.4 14.5 20.7 15.9 20.2 24.3 15.3 17.6 39.6 17.1 11.4 23.0 27.7 17.7 19.2 29.0 15.4 27.5 20.1 13.3 17.9 17.3 19.1 22.2 17.0 22.1 27.7 19.2 13.3 12.8 24.3 15.1 39.0 20.2 19.5 18.0 11.5 31.7 16.3 27.9 31.3 11.5 12.8 29.0 23.5 21.6 20.2 20.2 20.0 18.8 22.6 23.4 33.3 9.7 13.1 17.9 5.4 7.1 8.4 4.1 8.3 3.9 4.2 3.8 5.0 5.8 3.4 4.3 4.0 12.5 5.2 8.9 8.0 1.9 4.7 15.1 25.2 10.2 20.6 19.2 5.2 10.8 6.1 11.3 3.7 7.7 12.5 17.6 16.0 19.1 45.1 32.9 26.6 20.8 25.7 26.7 60.2 30.0 22.0 33.8 40.0 23.0 11.0 54.2 47.0 35.2 41.1 13.7 23.1 14.4 35.6 23.8 19.1 21.6 28.0 46.7 23.6 27.9 23.2 23.0 45.3 7.6 18.1 22.5 46.1 26.0 74.0 41.7 29.9 10.2 55.7 51.1 30.4 31.7 37.1 21.4 31.9 43.3 42.3 25.7 37.7 44.2 31.6 24.0 44.4 27.1 30.3 50.2 44.8 41.1 44.9 46.0 30.5 30.0 46.8 36.8 38.5 34.1 104.7 25.7 24.2 31.4 27.1 PDSS1 "COQ1, COQ1A, TPRT, TPT" ENSG00000148459 "Decaprenyl diphosphate synthase subunit 1" Q5T2R2 10 26697701-26746798 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isoprene biosynthesis, Ubiquinone biosynthesis" Transferase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 19.1;lymphoid tissue: 13.8" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 32.5;Proximal enterocytes: 29.8;Undifferentiated cells: 29.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038032, HPA042741" Uncertain Approved Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA038032: AB_10670650, HPA042741: AB_2678139" "unprognostic (1.41e-2)" "unprognostic (3.92e-1)" "unprognostic (8.92e-3)" "prognostic unfavorable (1.66e-4)" "unprognostic (6.79e-3)" "unprognostic (5.43e-2)" "prognostic unfavorable (1.25e-5)" "unprognostic (2.47e-2)" "unprognostic (9.43e-2)" "unprognostic (2.33e-2)" "unprognostic (2.20e-1)" "unprognostic (4.11e-2)" "unprognostic (2.99e-3)" "unprognostic (2.93e-3)" "unprognostic (8.85e-2)" "unprognostic (9.83e-2)" "unprognostic (6.36e-2)" 2.1 1.4 0.8 5.3 0.9 5.8 2.3 2.6 1.4 1.8 0.6 14.1 19.1 1.9 1.3 4.3 1.5 1.6 2.8 0.8 0.8 6.2 3.6 2.2 4.0 0.8 0.9 1.7 1.3 2.2 0.8 2.4 0.9 1.5 15.1 1.9 1.8 1.3 5.7 1.4 15.3 2.9 0.8 1.8 2.8 2.8 0.9 13.8 1.2 9.5 4.7 3.1 2.2 1.1 15.6 11.8 8.9 16.3 2.9 5.4 12.2 14.0 3.6 20.0 13.7 18.3 8.4 35.0 7.2 7.0 7.6 19.2 28.6 21.8 16.7 14.7 23.6 30.4 9.9 13.6 4.3 20.3 11.6 6.8 9.2 19.0 5.0 3.5 10.7 22.8 28.4 9.3 14.4 24.9 64.6 14.7 17.9 24.9 11.3 29.6 25.1 25.5 12.0 7.3 25.7 15.8 13.5 27.6 15.9 9.2 9.9 23.7 6.8 11.1 17.9 22.9 22.5 3.6 14.1 25.6 10.9 51.3 8.7 0.0 2.8 0.5 0.4 2.3 1.0 0.2 0.8 0.6 2.6 2.4 1.6 0.7 0.1 0.4 1.2 0.7 0.0 0.7 0.8 0.9 2.6 1.4 0.8 0.8 0.8 0.9 0.9 0.8 0.9 1.1 3.6 0.0 0.0 18.9 4.8 6.9 3.6 5.7 8.0 2.9 4.4 5.1 2.2 5.7 3.9 3.7 4.2 7.7 4.9 11.7 7.9 6.1 12.0 2.1 3.8 2.7 10.8 8.4 16.9 3.9 12.4 3.4 10.2 3.3 0.0 3.7 1.8 4.5 8.8 1.7 32.5 13.0 6.1 5.3 2.7 4.1 2.1 7.7 1.8 5.6 6.2 1.2 1.0 6.6 6.5 5.6 9.8 2.6 9.1 3.7 29.8 26.3 2.1 4.9 0.0 4.1 6.5 12.5 9.4 13.6 3.1 6.3 4.8 4.6 29.8 3.3 PDSS2 "bA59I9.3, C6orf210, COQ1B" ENSG00000164494 "Decaprenyl diphosphate synthase subunit 2" Q86YH6 6 107152562-107459564 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isoprene biosynthesis, Ubiquinone biosynthesis" Transferase "Cancer-related genes, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 82.4;Oligodendrocyte precursor cells: 72.9;Oligodendrocytes: 74.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029685, HPA029686" Approved Supported Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA029685: AB_10600219, HPA029686: AB_10602309" "prognostic unfavorable (1.34e-5)" "unprognostic (1.44e-1)" "prognostic favorable (5.74e-5)" "unprognostic (5.76e-2)" "unprognostic (1.42e-1)" "unprognostic (3.30e-2)" "unprognostic (3.26e-2)" "unprognostic (1.42e-1)" "unprognostic (1.15e-1)" "unprognostic (1.18e-1)" "unprognostic (9.38e-2)" "unprognostic (2.19e-1)" "prognostic favorable (3.75e-7)" "unprognostic (2.25e-1)" "unprognostic (2.86e-1)" "unprognostic (1.29e-1)" "unprognostic (2.11e-2)" 7.9 17.9 4.6 6.3 5.2 9.0 8.1 6.1 5.7 9.2 6.8 12.4 9.3 6.8 6.5 8.6 8.6 8.7 13.9 4.6 5.2 21.6 27.1 8.0 7.6 4.9 4.7 9.1 8.4 13.2 8.5 6.8 5.0 14.6 13.2 6.0 15.3 7.4 12.5 6.3 9.6 8.5 4.7 6.7 9.6 7.7 5.3 8.1 13.3 13.7 7.1 7.6 6.1 6.1 7.6 10.0 8.3 13.2 14.2 18.0 19.2 13.1 16.5 12.4 11.8 10.0 10.8 14.4 11.7 14.7 13.1 10.2 20.3 16.5 16.7 9.1 9.8 14.4 11.4 16.9 15.0 18.5 11.1 13.5 19.1 19.5 15.3 10.8 13.1 16.5 20.7 19.0 12.2 9.3 5.4 19.7 5.3 17.3 12.7 9.7 7.4 11.7 15.2 10.2 8.2 7.1 9.0 15.4 19.7 9.0 12.7 22.3 8.3 8.8 5.2 12.4 11.4 5.3 6.8 11.3 16.3 27.4 16.3 3.2 5.1 2.8 3.7 5.9 5.9 4.7 3.8 4.7 7.0 5.5 5.0 4.8 0.6 3.6 9.9 3.3 5.5 3.4 4.6 5.2 6.1 5.7 4.6 5.2 4.9 4.7 5.0 4.7 5.3 6.1 11.4 16.0 19.1 64.9 12.3 4.2 13.8 11.7 13.6 8.2 9.7 8.3 17.4 12.8 13.9 14.7 2.1 26.9 8.3 15.1 35.2 12.7 37.3 16.3 9.3 8.4 10.3 8.0 53.5 14.5 17.3 9.5 8.2 10.9 14.0 11.9 7.5 32.6 11.8 6.7 67.3 15.3 14.2 9.8 5.1 12.7 5.3 10.2 7.2 82.4 8.5 11.8 6.2 72.9 74.5 13.7 14.4 9.4 13.0 12.2 14.2 40.8 21.0 11.5 26.3 8.7 7.9 21.7 11.5 14.3 5.8 11.9 9.8 13.4 17.0 12.5 PEAK3 "C19orf35, FLJ45778" ENSG00000188305 "PEAK family member 3" Q6ZS72 19 2274631-2282175 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.3;lymphoid tissue: 4.1" "Cell type enhanced" "Detected in some" "dendritic cells: 1.5;Hofbauer cells: 1.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 41.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 41.0" "Cell line enriched" "Detected in some" 9 "HMC-1: 12.2" "Group enriched" "Detected in some" 5 "basal ganglia: 6.7;cerebellum: 3.1" HPA057806 Uncertain Uncertain Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "HPA057806: AB_2683534" "unprognostic (9.42e-2)" "unprognostic (3.26e-2)" "unprognostic (7.27e-2)" "unprognostic (6.23e-2)" "unprognostic (2.65e-2)" "unprognostic (8.40e-3)" "unprognostic (3.67e-1)" "unprognostic (3.08e-1)" "unprognostic (1.81e-1)" "unprognostic (2.08e-1)" "unprognostic (6.89e-2)" "unprognostic (1.43e-1)" "unprognostic (2.19e-2)" "unprognostic (2.01e-1)" "unprognostic (3.57e-2)" "unprognostic (3.20e-2)" "unprognostic (1.90e-1)" 0.5 0.4 0.5 1.3 0.9 2.3 0.3 0.5 1.6 0.2 0.1 0.4 0.2 0.2 0.0 0.2 0.5 0.2 0.7 0.4 0.5 0.3 0.2 1.1 0.4 1.4 1.0 0.1 0.2 0.0 0.2 0.1 1.0 0.3 0.2 0.0 0.2 0.0 0.3 0.3 0.8 0.1 0.9 4.1 0.3 0.1 0.8 0.1 0.2 0.0 0.3 0.3 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.4 0.0 12.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 10.5 4.4 11.7 1.6 5.7 0.2 0.2 0.1 0.2 1.8 0.4 0.1 0.3 41.0 4.5 1.9 0.2 0.0 1.1 0.5 0.9 0.5 1.6 0.4 0.5 1.4 1.0 1.0 0.9 0.8 0.6 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 PER3 ENSG00000049246 "Period circadian regulator 3" P56645 1 7784320-7845177 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 137.8;Bipolar cells: 241.0;Horizontal cells: 124.5;Rod photoreceptor cells: 138.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-937: 36.0" "Low region specificity" "Detected in all" HPA019530 Approved Supported Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Cytosol "HPA019530: AB_1855201" "unprognostic (5.11e-2)" "prognostic favorable (7.14e-4)" "unprognostic (2.45e-2)" "unprognostic (2.97e-3)" "unprognostic (1.74e-1)" "prognostic favorable (1.34e-4)" "unprognostic (3.87e-1)" "unprognostic (5.53e-2)" "unprognostic (1.43e-1)" "unprognostic (1.77e-1)" "unprognostic (4.11e-2)" "unprognostic (8.96e-2)" "prognostic favorable (2.20e-5)" "unprognostic (1.16e-1)" "unprognostic (1.20e-1)" "unprognostic (3.46e-1)" "unprognostic (1.62e-1)" 13.9 11.1 10.1 4.6 14.1 0.7 12.6 46.1 15.9 12.4 3.1 18.4 6.4 19.0 10.6 17.0 12.6 12.2 22.3 9.6 9.9 12.5 25.6 12.0 4.7 12.7 13.9 18.5 17.0 19.8 16.9 2.7 14.4 15.6 6.6 55.9 25.4 20.5 28.7 13.4 9.4 10.7 11.8 9.0 17.4 8.8 14.4 4.6 23.3 24.3 7.2 10.3 10.4 26.0 7.2 2.1 6.1 1.8 1.1 0.6 1.8 3.0 5.5 5.5 7.6 8.6 27.7 3.2 1.6 12.4 9.4 3.3 22.1 1.4 8.3 0.2 1.2 22.7 8.3 1.3 6.8 0.7 7.6 3.0 2.4 6.0 6.1 11.4 2.0 1.6 18.7 5.8 2.4 5.7 12.7 10.2 3.3 16.0 5.9 11.0 2.2 0.2 3.1 1.3 7.9 8.5 26.3 0.1 11.0 6.1 6.6 1.0 4.2 14.9 21.4 4.6 4.0 0.8 0.5 2.7 10.5 36.0 21.2 0.3 0.6 0.4 1.5 0.7 1.8 0.6 0.7 1.4 0.7 0.2 0.6 0.7 0.0 0.3 1.3 0.5 1.3 0.6 10.1 14.1 46.1 15.9 9.6 9.9 12.7 13.9 14.4 11.8 14.4 26.0 45.0 19.2 12.1 137.8 3.9 30.1 13.1 4.3 40.5 241.0 14.3 17.3 17.0 8.6 9.9 9.2 81.3 1.7 3.0 5.0 9.8 3.2 16.5 4.4 19.6 17.5 6.6 0.0 42.8 4.8 0.5 33.6 20.4 4.3 26.0 6.9 10.8 28.1 9.4 124.5 64.1 4.0 12.2 8.5 14.8 5.8 12.5 11.2 12.4 40.3 3.4 91.2 2.1 62.4 91.6 5.7 1.6 27.4 3.3 9.7 5.0 5.2 9.7 138.5 6.6 39.2 25.4 22.2 23.2 32.9 25.6 0.5 5.9 11.5 1.7 8.6 PFDN2 ENSG00000143256 "Prefoldin subunit 2" Q9UHV9 1 161100556-161118055 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 641.9;Suprabasal keratinocytes: 642.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028700, HPA058304" Approved Enhanced Cytosol NA NA 85000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA028700: AB_10603983, HPA058304: AB_2683673" "unprognostic (2.56e-1)" "unprognostic (2.76e-2)" "unprognostic (1.01e-2)" "unprognostic (2.62e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (9.10e-4)" "unprognostic (9.59e-3)" "unprognostic (1.00e-1)" "unprognostic (1.45e-1)" "unprognostic (1.50e-2)" "unprognostic (8.46e-2)" "unprognostic (5.61e-2)" "prognostic unfavorable (4.39e-8)" "unprognostic (1.01e-1)" "unprognostic (1.55e-1)" "unprognostic (1.52e-1)" "unprognostic (3.66e-2)" 99.3 80.2 157.9 55.4 167.4 110.5 71.6 168.7 195.3 59.5 144.7 65.7 43.9 59.2 67.2 73.9 57.7 39.7 103.1 159.4 180.9 95.5 103.2 71.0 64.0 171.8 173.3 60.0 49.8 53.5 100.5 57.0 171.8 54.3 41.9 53.6 50.9 45.6 183.3 54.0 46.8 46.3 165.8 54.5 52.8 58.6 169.4 67.1 48.5 114.5 61.3 82.6 59.9 176.0 305.9 205.3 154.0 201.1 141.3 134.1 167.2 218.4 205.1 190.9 150.6 274.2 228.4 204.6 252.4 148.1 185.6 220.0 241.6 279.1 235.2 224.6 236.3 226.1 322.4 394.9 405.9 314.5 217.1 149.0 362.8 305.6 877.0 144.1 222.4 208.9 343.6 142.6 177.8 316.4 237.2 372.6 300.1 359.7 495.8 200.4 154.9 249.8 212.1 186.7 202.5 334.1 168.3 224.3 367.6 200.5 184.9 394.3 188.9 195.4 283.8 245.1 472.2 211.6 226.3 403.5 236.7 214.2 273.1 112.6 104.8 115.5 58.5 107.5 66.9 116.6 72.5 72.1 129.2 120.0 74.7 72.1 54.1 66.1 135.1 201.5 98.8 73.5 157.9 167.4 168.7 195.3 159.4 180.9 171.8 173.3 171.8 165.8 169.4 176.0 178.2 32.1 39.7 13.1 94.6 641.9 320.5 407.2 124.7 76.3 105.5 140.2 125.2 62.9 163.9 115.8 16.7 183.1 114.3 83.6 342.4 168.0 36.1 152.7 140.4 162.3 101.3 93.0 21.5 150.6 242.9 157.2 55.5 176.1 99.5 116.8 97.5 143.5 175.0 21.9 21.8 97.3 248.2 64.2 399.6 26.9 126.5 120.0 184.9 7.5 123.8 94.8 80.3 11.6 62.4 230.3 78.9 110.2 79.1 426.2 86.2 281.2 135.0 77.6 78.9 135.7 298.2 142.7 269.8 153.3 642.6 179.6 113.8 137.3 95.9 355.6 PFKP "PFK-C, PFKF" ENSG00000067057 "Phosphofructokinase, platelet" Q01813 10 3066333-3137718 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 277.0" "Cell type enhanced" "Detected in many" "Early spermatids: 459.8;Late spermatids: 516.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018257, HPA056484" Uncertain Supported Cytosol No No 1900000 "Cluster 10: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 34: Spermatids - Unknown function" Cytosol "HPA018257: AB_10960391, HPA056484: AB_2683147" "unprognostic (1.16e-1)" "unprognostic (2.41e-3)" "unprognostic (5.79e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.55e-4)" "prognostic unfavorable (8.72e-6)" "unprognostic (1.36e-3)" "unprognostic (2.38e-1)" "unprognostic (8.51e-2)" "unprognostic (2.37e-2)" "unprognostic (8.82e-2)" "unprognostic (6.02e-3)" "unprognostic (2.60e-2)" "unprognostic (9.74e-2)" "unprognostic (2.06e-1)" "unprognostic (4.54e-3)" 35.0 11.5 41.6 41.5 39.3 14.4 23.5 13.8 49.9 26.3 61.7 43.8 48.8 55.5 5.6 67.1 34.9 34.1 128.6 60.4 65.0 44.6 4.7 19.1 32.5 30.7 50.9 19.1 15.9 15.2 29.9 15.5 58.0 35.6 30.7 277.0 39.8 62.0 70.4 40.3 59.6 44.1 8.3 19.1 36.8 141.1 47.0 29.7 38.5 21.0 21.2 64.7 42.8 31.7 314.8 420.2 25.9 0.6 26.8 56.9 336.9 187.2 66.6 186.2 222.8 444.5 320.4 37.0 147.8 134.9 174.9 243.0 141.7 292.3 173.1 102.1 111.0 132.0 189.1 24.2 65.2 53.7 203.4 27.0 61.2 190.0 96.0 273.7 367.8 153.7 37.0 1.3 195.7 239.8 182.5 44.4 42.9 133.9 149.3 138.8 46.9 150.1 185.7 115.9 69.5 64.7 133.7 111.0 172.0 307.8 93.7 80.3 449.2 124.6 65.3 380.5 199.3 195.4 200.1 135.7 331.0 98.0 78.5 30.8 8.5 2.9 26.8 4.2 21.2 13.7 26.2 25.0 14.5 15.3 9.6 15.4 1.3 26.7 1.6 22.5 37.6 16.5 41.6 39.3 13.8 49.9 60.4 65.0 30.7 50.9 58.0 8.3 47.0 31.7 30.5 3.2 7.0 128.6 14.8 28.7 58.5 96.8 14.8 40.4 10.3 7.7 147.4 8.6 57.9 64.4 54.2 7.8 16.3 72.6 43.0 115.7 459.8 41.2 9.0 36.0 37.2 10.3 49.4 10.8 205.8 25.9 35.7 63.8 55.9 25.8 14.6 0.7 33.9 42.1 25.9 23.1 124.1 7.6 31.4 516.3 7.5 14.3 19.6 15.0 15.4 113.1 16.5 16.1 6.7 116.8 57.2 6.8 14.2 80.9 53.2 5.9 62.6 133.4 13.1 43.2 34.6 149.4 3.5 25.1 22.6 26.5 28.8 11.2 28.9 64.2 PFN1 ENSG00000108518 "Profilin 1" P07737 17 4945652-4949061 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 5241.0;monocytes: 4824.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037134, CAB037140" Enhanced Approved Cytosol NA NA 660000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 3: Monocytes - Immune response regulation" Cytosol "CAB037134: AB_1079599, CAB037140: AB_1079598" "unprognostic (1.07e-1)" "unprognostic (3.57e-1)" "unprognostic (1.60e-1)" "unprognostic (5.45e-3)" "unprognostic (1.65e-1)" "unprognostic (7.54e-2)" "unprognostic (4.01e-3)" "unprognostic (7.83e-3)" "unprognostic (3.38e-1)" "unprognostic (1.09e-3)" "unprognostic (2.17e-1)" "unprognostic (3.40e-2)" "prognostic unfavorable (1.06e-4)" "unprognostic (3.62e-1)" "unprognostic (8.17e-2)" "unprognostic (1.02e-2)" "unprognostic (1.28e-1)" 573.1 365.8 278.0 1133.4 302.0 1613.0 397.0 323.2 333.0 393.7 289.2 970.2 764.0 734.4 346.4 582.7 500.9 372.7 343.8 281.8 301.5 460.9 661.6 559.2 1357.9 347.3 325.4 247.7 246.4 311.3 198.9 581.1 348.6 419.4 808.4 71.8 346.9 601.4 337.9 449.8 772.9 1034.7 315.2 910.8 675.1 116.2 366.2 1197.6 269.2 238.7 1440.0 842.6 425.0 355.2 3019.5 4276.8 1461.5 1205.2 778.8 977.1 1972.7 2416.8 1970.4 2568.6 1923.7 1684.1 1181.1 2476.9 1892.0 2542.0 1453.6 1825.4 1383.6 3040.5 2049.6 3560.1 2355.1 2516.6 2034.3 2225.8 2144.0 1630.4 5006.0 1152.4 1331.9 1957.6 1939.8 1477.6 2361.3 1646.4 1488.6 1736.7 3150.5 1815.0 2469.9 3448.0 2095.2 1474.7 2297.3 2451.9 2035.1 1494.6 2491.7 1909.8 564.0 1586.2 1910.5 1180.9 1679.7 1226.8 1121.0 1359.7 2731.7 2136.6 1675.1 1512.3 3969.3 931.3 1070.7 1799.3 1834.4 1949.7 3316.4 8100.1 8206.3 13914.4 9850.0 10858.8 6780.3 5722.0 8185.7 9586.6 9920.0 4970.0 5238.0 7604.7 9387.0 9112.1 13547.4 7809.7 11245.6 23570.1 278.0 302.0 323.2 333.0 281.8 301.5 347.3 325.4 348.6 315.2 366.2 355.2 561.8 112.2 176.1 12.1 1070.6 1806.0 873.2 3658.3 1003.3 25.0 767.4 914.1 147.6 457.5 1020.0 741.2 0.0 1911.0 1725.6 1733.8 992.0 1866.6 19.7 313.4 546.1 806.6 603.7 713.5 7.1 1625.2 5241.0 599.9 733.4 422.7 486.5 291.2 637.5 754.3 4094.2 38.7 6.4 1399.7 1452.6 1434.3 2934.8 31.0 263.8 1854.7 873.4 21.5 4824.7 99.8 3216.3 9.0 37.2 2933.5 1585.7 375.0 927.8 1238.2 1472.2 1671.2 559.4 17.8 506.2 282.3 1838.4 97.4 355.4 1170.1 1513.5 1682.8 1804.7 410.7 1355.5 1177.9 PGGHG "ATHL1, FLJ22635" ENSG00000142102 "Protein-glucosylgalactosylhydroxylysine glucosidase" Q32M88 11 289126-296107 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "pancreas: 657.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 160.3;Alveolar cells type 2: 81.8;Breast glandular cells: 35.1;Club cells: 31.6;Collecting duct cells: 33.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "JURKAT: 132.8;U-266/70: 34.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA039383, HPA058829" Uncertain Enhanced Cytosol NA Yes "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 25: Pancreas - Digestion" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" Cytosol "HPA039383: AB_10796225, HPA058829: AB_2683830" "unprognostic (1.40e-3)" "unprognostic (2.18e-1)" "unprognostic (4.22e-2)" "unprognostic (2.37e-1)" "unprognostic (1.36e-2)" "unprognostic (5.83e-2)" "unprognostic (7.95e-3)" "unprognostic (2.77e-2)" "unprognostic (2.16e-2)" "unprognostic (2.14e-2)" "unprognostic (2.71e-2)" "unprognostic (3.45e-1)" "unprognostic (1.92e-3)" "unprognostic (2.85e-3)" "unprognostic (1.09e-2)" "unprognostic (1.22e-1)" "prognostic favorable (5.12e-4)" 25.3 5.6 5.8 41.6 5.8 16.3 41.9 5.5 25.6 56.0 6.8 25.2 50.5 21.6 32.7 14.1 34.6 18.9 18.8 5.4 5.8 116.4 77.8 67.0 63.5 6.9 6.4 8.7 657.7 2.9 12.5 7.3 8.2 34.6 6.3 0.6 36.2 46.1 4.5 8.6 103.0 3.0 5.7 101.9 18.5 6.3 7.1 37.4 74.4 3.2 17.6 21.5 22.6 6.3 5.4 5.8 10.5 11.7 4.2 3.7 8.2 4.2 3.4 2.4 2.1 5.0 15.0 0.0 5.3 5.1 5.1 3.3 0.9 1.9 0.3 13.3 4.0 2.5 4.2 6.8 5.3 0.3 22.8 13.8 1.5 0.9 0.7 8.9 8.1 132.8 10.5 15.9 1.3 7.7 24.0 12.1 8.3 1.8 1.0 21.5 2.1 7.8 5.6 1.8 0.1 2.4 1.5 7.8 7.2 4.6 5.7 2.9 7.5 4.9 7.0 1.5 0.5 34.8 1.0 6.0 0.8 4.3 5.8 1.2 0.7 1.0 6.1 3.2 5.1 1.5 1.0 3.3 0.5 1.5 2.1 4.5 3.7 5.6 2.5 2.0 0.1 2.2 5.8 5.8 5.5 25.6 5.4 5.8 6.9 6.4 8.2 5.7 7.1 6.3 17.8 160.3 81.8 0.0 9.1 0.0 0.0 0.0 0.0 0.0 35.1 26.8 0.0 0.0 31.6 33.1 0.0 0.3 29.8 0.0 0.0 4.9 0.0 12.5 12.0 4.5 0.0 0.0 0.0 8.3 3.3 4.2 0.0 17.6 6.3 1.5 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 1.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 16.1 0.0 0.0 2.9 10.2 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.3 14.4 0.9 0.0 0.0 PGM1 ENSG00000079739 "Phosphoglucomutase 1" P36871 1 63593411-63660245 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" Isomerase "Congenital disorder of glycosylation, Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 1559.1;tongue: 788.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 238.4;Extravillous trophoblasts: 185.9;Hepatocytes: 214.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004666, HPA024190, HPA024637, HPA046329" Enhanced Supported Cytosol NA NA 21000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "CAB004666: AB_425590, HPA024190: AB_1855266, HPA024637: AB_1855267, HPA046329: AB_2679625" "unprognostic (2.50e-1)" "unprognostic (2.26e-3)" "unprognostic (1.74e-2)" "unprognostic (5.90e-2)" "unprognostic (1.65e-1)" "unprognostic (1.63e-1)" "unprognostic (1.28e-2)" "unprognostic (1.86e-3)" "unprognostic (2.42e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (8.74e-5)" "unprognostic (7.07e-2)" "unprognostic (1.55e-2)" "unprognostic (6.58e-3)" "unprognostic (1.37e-1)" "unprognostic (2.46e-1)" "unprognostic (9.74e-3)" 113.7 70.8 31.6 20.7 34.7 21.5 57.4 34.3 38.4 33.9 53.1 58.9 60.8 22.9 19.2 49.3 17.0 30.3 178.9 31.4 34.0 52.2 279.8 42.6 14.7 44.7 34.1 51.0 112.2 65.3 31.8 26.9 32.7 46.6 49.9 22.6 41.8 49.7 1559.1 30.6 55.1 41.4 31.9 14.7 30.6 11.1 36.5 14.3 27.5 788.0 19.4 38.4 22.1 30.2 113.4 47.0 17.3 57.0 111.0 81.4 138.6 45.7 61.8 48.9 79.0 38.8 51.3 35.8 93.2 71.2 107.4 26.5 24.0 96.3 55.9 44.0 32.1 75.3 72.6 40.3 91.6 66.8 4.3 103.4 60.7 57.1 88.5 129.8 29.6 36.3 0.1 46.3 78.8 6.9 19.6 36.7 78.3 3.4 73.9 26.8 80.0 11.8 70.0 35.3 10.4 66.7 100.0 103.0 157.4 78.6 32.4 25.2 3.1 71.6 36.0 64.0 39.4 29.1 45.5 57.8 117.0 58.0 31.5 46.0 33.2 49.2 40.5 22.4 32.7 22.4 23.5 31.0 48.4 11.8 21.0 24.7 38.7 43.9 21.2 13.9 20.4 35.4 31.6 34.7 34.3 38.4 31.4 34.0 44.7 34.1 32.7 31.9 36.5 30.2 8.4 93.0 29.4 48.3 16.9 17.8 29.0 58.8 47.8 9.2 33.8 21.8 139.2 48.6 24.2 16.5 10.4 76.6 14.2 81.8 88.0 55.9 32.0 8.2 12.1 12.7 13.1 5.7 17.9 238.4 185.9 37.0 27.0 13.5 5.1 134.3 15.0 214.4 24.6 0.0 26.3 47.5 20.3 17.0 10.8 8.5 22.1 13.5 26.6 4.7 32.8 75.8 29.9 32.2 9.8 70.5 31.6 38.0 40.4 29.2 90.2 74.8 17.0 11.4 13.1 53.4 25.5 5.6 10.1 57.3 18.2 58.8 19.0 20.2 81.5 19.0 PGM5 PGMRP ENSG00000154330 "Phosphoglucomutase 5" Q15124 9 68328308-68531061 "Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Cell adhesion, Glucose metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 269.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 107.2;Endothelial cells: 36.6;Hepatic stellate cells: 39.3;Microglial cells: 124.6;Sertoli cells: 52.6;Smooth muscle cells: 35.9" "Cancer enhanced" "Detected in many" "prostate cancer: 16.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 48 "neutrophil: 4.8" "Lineage enriched" "Detected in single" 48 "granulocytes: 4.8" "Group enriched" "Detected in some" 5 "hTERT-RPE1: 28.7;PC-3: 56.5;RH-30: 38.8;SK-BR-3: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034397, HPA046329, HPA067102" Enhanced Uncertain Cytosol NA NA 450000 "Cluster 1: Neutrophils - Mixed function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB034397: AB_1118633, HPA046329: AB_2679625, HPA067102: AB_2732758" "unprognostic (3.43e-1)" "unprognostic (2.17e-2)" "unprognostic (3.98e-3)" "unprognostic (5.75e-2)" "unprognostic (1.10e-1)" "unprognostic (1.09e-1)" "unprognostic (3.15e-4)" "unprognostic (1.22e-3)" "unprognostic (2.79e-1)" "unprognostic (5.28e-3)" "unprognostic (4.78e-2)" "unprognostic (2.28e-2)" "prognostic favorable (1.83e-5)" "unprognostic (3.04e-2)" "unprognostic (2.91e-1)" "unprognostic (2.48e-1)" "unprognostic (4.73e-2)" 28.9 61.0 3.7 12.6 4.1 0.0 21.0 5.8 3.8 51.7 3.3 269.4 15.4 154.0 40.8 98.6 96.5 19.6 126.1 3.1 4.1 11.5 5.1 14.6 5.8 4.6 4.0 19.8 2.7 5.0 4.3 5.8 4.3 159.0 34.2 8.0 6.7 214.0 37.5 11.1 72.0 132.5 4.7 10.8 65.2 3.0 4.6 2.9 13.1 30.5 2.9 216.7 40.6 4.6 0.2 0.2 0.0 0.0 0.7 0.0 0.3 8.2 6.3 3.8 1.7 0.0 0.0 0.2 0.0 0.0 0.1 0.1 9.2 0.0 9.4 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.0 0.0 28.7 0.0 0.0 0.0 0.1 0.0 4.1 0.1 0.7 0.0 0.0 56.5 0.0 38.8 1.8 1.5 0.0 0.0 0.2 0.1 47.8 2.8 1.2 0.0 0.0 0.1 0.0 5.7 0.3 0.3 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 3.7 4.1 5.8 3.8 3.1 4.1 4.6 4.0 4.3 4.7 4.6 4.6 21.6 0.0 1.7 0.7 0.2 2.3 5.6 0.0 0.6 25.3 0.2 1.5 107.2 2.8 1.8 12.9 4.2 0.0 0.1 0.1 1.9 0.1 1.8 3.7 2.8 36.6 0.0 4.0 1.4 0.0 0.2 12.4 0.0 1.1 0.0 18.7 39.3 0.1 0.1 0.0 1.7 2.7 0.0 4.0 2.8 0.5 8.1 2.1 3.6 124.6 1.0 8.3 0.0 1.0 2.3 0.1 0.1 4.9 0.0 2.1 0.8 1.2 0.8 1.9 52.6 1.7 35.9 0.1 0.2 0.4 2.4 0.0 0.6 30.0 1.6 1.5 PHKG2 ENSG00000156873 "Phosphorylase kinase catalytic subunit gamma 2" P15735 16 30748293-30761176 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Glycogen metabolism" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 130.1" "Group enriched" "Detected in many" 5 "Early spermatids: 397.0;Late spermatids: 1576.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065618, HPA068751" Supported Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA065618: AB_2685520, HPA068751: AB_2686025" "unprognostic (7.63e-3)" "prognostic favorable (7.90e-4)" "prognostic unfavorable (9.92e-4)" "unprognostic (1.08e-1)" "unprognostic (1.25e-1)" "unprognostic (5.81e-2)" "unprognostic (3.72e-2)" "prognostic favorable (1.90e-4)" "unprognostic (6.45e-2)" "unprognostic (1.25e-2)" "prognostic favorable (8.02e-4)" "unprognostic (6.15e-2)" "unprognostic (5.27e-2)" "unprognostic (1.36e-2)" "unprognostic (2.41e-1)" "unprognostic (2.18e-2)" "unprognostic (3.03e-2)" 9.0 15.8 17.5 11.5 16.9 30.0 9.9 17.1 18.7 10.0 15.9 12.9 11.0 10.1 9.5 10.2 11.7 8.2 12.1 18.9 16.4 14.7 19.1 10.0 12.5 17.7 17.2 8.3 9.7 18.9 15.9 7.8 18.8 14.7 12.0 8.9 11.5 12.0 13.2 14.6 12.0 9.9 16.0 12.9 13.8 130.1 17.5 11.6 13.6 8.8 12.7 10.1 9.2 16.2 24.7 16.3 13.1 16.2 11.8 9.4 29.8 17.2 24.6 22.1 25.1 13.5 12.6 21.0 19.3 17.1 11.5 24.0 13.5 21.5 17.6 11.4 38.2 11.9 28.8 38.7 18.1 18.1 16.9 12.9 11.2 21.4 9.9 10.7 22.8 15.3 16.1 11.7 16.3 55.5 22.3 27.1 18.0 17.6 18.0 29.4 20.0 28.2 25.7 27.2 17.5 11.9 13.5 38.1 16.6 11.8 30.1 15.5 13.6 14.4 15.1 17.2 16.0 24.1 14.4 14.8 27.3 35.2 11.4 44.0 55.8 114.9 37.8 56.5 30.9 21.1 27.1 38.8 52.0 21.5 24.2 27.7 44.7 63.8 42.3 46.1 43.3 49.0 17.5 16.9 17.1 18.7 18.9 16.4 17.7 17.2 18.8 16.0 17.5 16.2 10.4 12.8 21.7 13.7 18.5 21.0 15.2 28.7 22.8 8.8 21.8 17.1 15.9 10.0 32.0 18.4 10.4 29.6 32.2 32.1 27.4 11.9 397.0 35.8 13.0 10.0 16.3 20.2 14.7 24.4 41.5 11.8 44.4 38.8 13.3 16.1 10.4 24.1 28.2 20.2 14.5 21.4 26.4 19.1 27.2 1576.6 17.4 26.4 12.4 11.2 40.3 13.7 39.1 9.0 8.1 19.6 18.5 23.3 20.5 31.5 27.8 47.3 33.0 9.9 0.0 8.9 14.8 180.5 22.9 20.5 23.0 75.5 25.9 20.8 27.0 16.9 PHYHIPL "Em:AC025038.1, KIAA1796" ENSG00000165443 "Phytanoyl-CoA 2-hydroxylase interacting protein like" Q96FC7 10 59176643-59247774 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 18.4;brain: 45.5;retina: 30.5" "Cell type enhanced" "Detected in many" "Astrocytes: 210.6;Early spermatids: 208.4;Horizontal cells: 144.7;Inhibitory neurons: 170.2;Late spermatids: 241.4;Muller glia cells: 246.1;Oligodendrocyte precursor cells: 264.9;Oligodendrocytes: 357.1" "Group enriched" "Detected in many" 5 "glioma: 21.1;renal cancer: 8.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 5.3;Hep G2: 34.3;SCLC-21H: 6.1;SH-SY5Y: 19.4;SK-BR-3: 8.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038746 Uncertain Approved Cytosol NA NA "Cluster 77: Retina - Visual perception" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 5: Muller glia cells - Visual perception" Cytosol "HPA038746: AB_10673293" "unprognostic (6.34e-3)" "unprognostic (2.40e-1)" "unprognostic (1.04e-1)" "unprognostic (3.76e-3)" "unprognostic (7.06e-2)" "unprognostic (3.37e-1)" "unprognostic (5.63e-2)" "unprognostic (3.78e-2)" "unprognostic (1.06e-1)" "unprognostic (4.00e-3)" "unprognostic (2.67e-3)" "unprognostic (2.02e-1)" "prognostic favorable (1.60e-7)" "unprognostic (1.29e-3)" "unprognostic (1.30e-1)" "unprognostic (5.88e-2)" "unprognostic (2.12e-1)" 0.3 18.4 22.5 0.4 30.1 0.0 0.4 31.6 36.9 1.6 0.3 2.1 8.5 0.7 1.8 0.3 1.1 0.1 0.3 21.2 36.1 11.0 1.1 0.2 0.0 41.3 32.1 0.8 5.4 0.0 6.7 1.8 32.8 2.8 0.3 30.5 0.7 2.6 0.6 0.3 8.9 0.1 42.4 0.1 0.6 6.5 26.2 0.0 0.2 0.0 0.0 0.1 1.2 45.5 0.0 0.6 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.1 19.4 0.0 8.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.5 30.1 31.6 36.9 21.2 36.1 41.3 32.1 32.8 42.4 26.2 45.5 3.1 0.0 0.0 210.6 0.0 0.0 14.0 0.0 0.0 135.2 0.2 1.0 0.5 2.8 0.0 3.7 12.5 1.0 0.0 0.1 13.7 0.6 208.4 24.1 8.0 1.6 0.0 2.7 97.3 6.5 0.3 1.2 0.0 71.9 0.0 0.8 0.7 1.8 0.5 144.7 170.2 3.0 0.0 0.0 0.0 241.4 13.1 1.3 1.8 11.2 0.0 246.1 0.0 264.9 357.1 1.7 6.3 0.4 0.0 4.0 24.0 80.3 0.0 53.9 0.0 3.0 2.4 137.1 27.2 0.1 0.0 49.0 0.6 0.3 9.6 2.8 PI4K2B "FLJ11105, PI4KIIB, PIK42B" ENSG00000038210 "Phosphatidylinositol 4-kinase type 2 beta" Q8TCG2 4 25160663-25279204 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 57.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004099 Enhanced Supported Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "HPA004099: AB_1855353" "unprognostic (1.02e-1)" "unprognostic (6.34e-3)" "prognostic favorable (9.64e-5)" "unprognostic (2.75e-2)" "unprognostic (1.98e-2)" "unprognostic (2.68e-2)" "unprognostic (7.54e-2)" "unprognostic (7.75e-2)" "unprognostic (5.06e-1)" "unprognostic (6.39e-3)" "unprognostic (1.71e-1)" "unprognostic (1.32e-1)" "unprognostic (9.07e-2)" "unprognostic (9.61e-2)" "unprognostic (2.39e-2)" "unprognostic (2.02e-2)" "unprognostic (4.47e-2)" 7.9 8.9 3.4 14.0 3.9 14.1 16.5 3.6 4.5 11.4 5.8 18.7 39.0 8.0 5.8 16.7 8.7 8.3 4.5 3.2 4.1 12.9 57.9 16.5 18.1 4.3 3.6 5.2 9.5 7.7 3.4 12.0 4.5 11.4 20.4 4.9 23.5 7.9 2.4 13.1 31.6 9.1 4.5 13.5 22.7 12.1 3.7 19.7 24.1 4.8 18.9 14.3 8.1 5.3 33.8 9.9 16.7 14.6 18.2 33.9 31.3 50.8 48.6 48.4 58.1 14.0 37.7 86.3 11.5 45.3 37.5 14.7 37.3 24.6 41.7 28.9 12.2 30.4 23.3 26.1 14.2 61.9 21.0 21.6 17.9 18.6 19.2 12.9 28.0 27.0 20.7 76.2 37.0 18.8 58.3 39.7 23.6 40.5 13.6 34.4 58.1 47.5 32.2 32.2 28.9 6.2 24.5 17.1 12.0 17.0 25.7 27.3 33.8 31.8 8.4 18.3 32.5 76.3 49.5 77.4 34.5 45.4 30.6 5.3 1.1 3.4 1.5 1.2 1.0 1.4 1.5 1.5 0.8 1.2 1.2 1.4 1.7 0.9 0.9 1.5 3.5 0.6 3.4 3.9 3.6 4.5 3.2 4.1 4.3 3.6 4.5 4.5 3.7 5.3 5.6 6.4 18.5 21.5 14.9 15.0 15.8 9.9 8.0 2.1 8.4 5.3 0.0 5.7 12.2 9.2 0.0 21.6 6.7 20.2 5.9 5.5 1.0 10.0 3.4 7.1 8.4 25.7 8.7 7.1 12.6 6.1 16.3 8.5 0.0 3.5 6.8 40.4 10.3 1.7 13.7 13.7 8.2 15.4 13.9 1.0 4.4 8.6 5.4 11.2 10.3 0.7 4.1 30.2 20.1 5.8 8.2 4.5 27.4 14.1 16.8 20.3 10.4 3.4 0.0 5.3 7.2 9.6 10.3 18.3 15.6 13.5 10.3 4.4 13.9 18.2 PICK1 "dJ1039K5, MGC15204, PRKCABP" ENSG00000100151 "Protein interacting with PRKCA 1" Q9NRD5 22 38056311-38075701 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 116.1;Late spermatids: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000819, HPA072674" Approved Supported Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "HPA000819: , HPA072674: AB_2686547" "unprognostic (1.97e-2)" "unprognostic (4.61e-3)" "unprognostic (7.79e-2)" "unprognostic (9.26e-2)" "unprognostic (1.29e-2)" "unprognostic (1.81e-1)" "unprognostic (6.04e-2)" "unprognostic (1.65e-2)" "unprognostic (4.62e-2)" "unprognostic (1.65e-1)" "unprognostic (1.68e-3)" "unprognostic (1.20e-1)" "unprognostic (8.56e-2)" "prognostic favorable (5.26e-5)" "unprognostic (1.36e-1)" "unprognostic (2.74e-1)" "unprognostic (4.61e-3)" 8.8 14.9 12.4 4.8 15.2 5.4 13.5 12.8 20.3 9.9 12.9 11.9 10.1 11.7 13.8 15.9 16.3 8.9 18.2 14.5 13.5 15.1 17.5 10.8 5.4 14.5 13.6 15.4 18.5 29.3 28.8 6.7 16.7 25.6 12.2 5.9 18.6 12.6 26.3 16.9 11.3 11.3 11.6 10.1 16.2 27.4 15.6 5.9 14.6 16.2 8.2 9.3 12.0 23.0 19.5 13.7 7.6 10.0 5.3 4.1 11.3 10.7 12.8 22.5 22.7 14.6 12.0 8.6 11.6 13.0 17.0 20.8 21.0 43.2 19.3 5.3 33.6 3.1 16.8 17.1 19.3 10.1 20.4 13.3 24.9 14.8 21.9 22.8 8.8 11.1 6.4 6.2 4.7 12.4 6.0 0.9 12.1 44.3 14.9 5.1 0.3 7.8 25.8 31.1 31.5 16.0 12.0 28.8 11.1 11.1 16.8 7.3 2.4 6.4 12.0 8.6 6.4 13.9 3.4 2.7 13.8 3.4 9.4 0.0 0.9 0.0 0.5 0.4 0.2 0.3 0.5 1.0 1.6 1.1 1.0 0.5 0.6 0.4 0.5 0.3 0.7 0.6 12.4 15.2 12.8 20.3 14.5 13.5 14.5 13.6 16.7 11.6 15.6 23.0 8.1 9.6 10.6 11.1 8.1 8.0 14.2 15.6 12.0 12.7 18.7 16.1 10.2 11.5 12.1 7.3 8.4 26.1 6.0 25.4 11.7 18.8 116.1 15.4 3.6 7.8 10.3 1.7 26.8 15.7 14.8 6.8 29.6 17.3 8.9 36.3 5.7 9.7 15.1 20.2 19.4 20.1 18.3 31.5 13.3 85.5 11.1 16.3 7.2 6.5 16.0 13.6 8.2 8.5 29.0 21.4 18.5 17.0 5.8 22.1 18.3 16.0 12.8 12.5 13.1 6.0 9.5 17.2 6.7 12.0 9.7 38.4 6.8 15.5 18.5 14.7 PIH1D1 "FLJ20643, MOT48, NOP17, Pih1" ENSG00000104872 "PIH1 domain containing 1" Q9NWS0 19 49446298-49453497 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047258 Approved Approved Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA047258: AB_10964561" "unprognostic (2.28e-1)" "unprognostic (1.56e-1)" "unprognostic (2.14e-1)" "unprognostic (8.99e-2)" "unprognostic (7.77e-3)" "unprognostic (9.66e-2)" "unprognostic (1.23e-3)" "unprognostic (1.93e-1)" "unprognostic (3.09e-1)" "unprognostic (8.38e-2)" "unprognostic (5.13e-2)" "unprognostic (1.22e-2)" "unprognostic (1.86e-2)" "unprognostic (2.03e-1)" "unprognostic (1.04e-1)" "unprognostic (2.48e-1)" "unprognostic (2.86e-2)" 38.0 37.1 31.4 26.8 32.0 34.5 37.1 31.5 39.5 38.0 33.8 40.4 43.5 32.4 13.2 45.0 39.7 27.0 31.5 33.0 31.8 41.4 47.7 30.5 43.6 31.7 30.9 29.9 39.7 50.4 34.5 33.1 32.0 39.6 29.5 11.8 49.5 33.8 67.5 45.3 37.2 26.3 31.9 39.4 41.3 17.8 33.1 46.1 37.1 57.6 36.1 33.0 39.4 31.8 133.6 67.0 84.6 130.3 40.1 37.2 54.0 52.9 68.8 79.8 122.3 72.4 89.6 89.1 48.6 56.7 20.0 79.9 44.8 96.6 46.2 85.5 85.1 79.9 89.6 93.0 63.1 86.7 115.3 43.5 40.4 59.0 55.8 74.8 74.8 79.2 119.5 76.8 50.5 59.9 98.4 173.3 101.1 118.4 63.2 83.1 93.6 90.4 65.1 107.2 109.2 158.0 54.3 91.2 53.2 41.1 44.0 104.3 44.9 66.9 52.0 26.9 84.2 205.5 172.8 49.8 36.6 93.6 47.5 166.8 104.5 121.0 88.3 104.0 75.6 116.1 98.8 94.9 105.1 110.1 79.5 73.4 11.8 103.7 108.7 100.2 158.3 107.0 31.4 32.0 31.5 39.5 33.0 31.8 31.7 30.9 32.0 31.9 33.1 31.8 45.5 38.5 36.6 10.7 54.8 55.8 61.9 80.2 59.7 20.9 46.8 50.0 11.2 41.5 46.4 20.2 18.8 101.7 48.8 48.6 62.6 74.1 18.1 47.4 24.1 39.2 57.5 33.4 10.5 46.3 116.5 59.9 43.8 30.6 52.6 30.8 35.3 44.3 71.2 23.5 8.5 63.9 38.7 40.8 55.7 9.9 62.4 40.7 64.0 11.2 59.0 55.0 40.2 10.1 10.9 47.3 75.4 47.0 60.3 65.6 90.2 115.9 59.4 22.6 26.3 44.5 46.8 40.6 29.9 49.0 67.1 94.0 50.4 48.2 59.4 66.2 PIK3R1 "GRB1, p85, p85-ALPHA" ENSG00000145675 "Phosphoinositide-3-kinase regulatory subunit 1" P27986 5 68215756-68301821 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction, Protein transport, Stress response, Transport" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "dendritic cells: 410.2;Endometrial stromal cells: 479.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 265.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001216, CAB004268" Approved Approved Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Cytosol "CAB004268: AB_628126, HPA001216: AB_1079612" "unprognostic (5.74e-2)" "unprognostic (6.58e-2)" "unprognostic (2.01e-1)" "unprognostic (1.31e-2)" "unprognostic (1.18e-1)" "unprognostic (1.33e-2)" "prognostic favorable (8.09e-4)" "unprognostic (3.78e-3)" "unprognostic (1.78e-1)" "unprognostic (2.71e-1)" "unprognostic (6.10e-2)" "unprognostic (1.32e-1)" "unprognostic (4.59e-3)" "unprognostic (5.66e-3)" "unprognostic (1.27e-1)" "unprognostic (5.92e-2)" "unprognostic (1.54e-1)" 60.6 27.3 13.6 27.8 33.3 126.4 92.1 12.5 40.8 51.2 0.6 38.2 17.2 65.8 45.0 43.2 69.0 35.0 72.3 29.9 13.0 35.9 100.8 26.7 28.5 11.2 22.1 53.3 13.4 40.2 7.3 32.4 12.0 26.7 22.2 59.9 64.5 31.9 63.5 28.7 24.5 74.8 9.9 38.1 18.3 8.6 20.3 46.5 20.6 33.9 23.7 27.0 31.7 36.0 4.3 8.2 23.8 71.4 265.5 76.9 10.4 23.2 10.6 8.8 9.4 20.4 7.4 21.8 38.5 32.0 4.3 10.2 6.7 46.9 11.0 90.6 8.9 26.1 6.5 17.0 89.2 27.0 20.1 81.9 104.2 16.1 83.6 4.1 11.7 25.0 4.1 16.1 8.1 11.3 65.7 10.5 6.9 14.7 4.3 61.1 11.3 17.0 11.5 47.9 4.7 21.3 4.0 6.3 15.0 13.7 34.3 19.0 14.0 10.3 10.4 17.3 14.8 18.0 29.2 25.2 11.1 32.9 7.8 22.0 1.7 8.8 11.5 2.4 16.6 1.7 14.9 11.1 3.0 3.9 18.6 14.1 2.2 11.7 6.5 1.2 12.3 5.5 13.6 33.3 12.5 40.8 29.9 13.0 11.2 22.1 12.0 9.9 20.3 36.0 47.7 51.3 24.8 112.3 47.7 14.4 23.5 30.8 175.2 46.0 61.4 168.4 263.0 38.6 19.3 5.5 25.0 13.4 410.2 28.4 72.4 15.8 12.6 38.7 479.9 39.0 9.6 43.5 232.8 9.5 18.5 151.0 43.8 93.2 68.9 110.4 31.1 198.3 30.7 48.8 82.7 32.6 28.5 69.2 24.7 11.9 172.1 68.8 33.8 117.1 37.6 194.1 137.0 281.5 199.9 12.3 19.8 122.2 173.2 8.4 24.3 39.1 8.7 89.4 19.7 127.2 76.5 1.7 4.5 37.2 10.2 10.0 309.9 45.4 36.5 8.1 PIM2 ENSG00000102096 "Pim-2 proto-oncogene, serine/threonine kinase" Q9P1W9 X 48913182-48919024 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 102.3;intestine: 87.6;lymphoid tissue: 163.9" "Cell type enriched" "Detected in many" 4 "Plasma cells: 738.8" "Cancer enriched" "Detected in all" 6 "testis cancer: 171.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 5 "HDLM-2: 567.6;Karpas-707: 675.0;RPMI-8226: 703.9;U-266/70: 1218.7;U-266/84: 1160.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000285 Approved Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "HPA000285: AB_1079619" "unprognostic (2.34e-3)" "prognostic favorable (4.05e-5)" "unprognostic (8.04e-2)" "unprognostic (7.30e-2)" "unprognostic (6.41e-3)" "unprognostic (2.74e-3)" "unprognostic (2.84e-1)" "unprognostic (5.23e-2)" "unprognostic (2.47e-2)" "unprognostic (4.01e-2)" "unprognostic (1.33e-3)" "unprognostic (2.73e-1)" "prognostic unfavorable (1.17e-11)" "unprognostic (3.36e-2)" "unprognostic (1.96e-2)" "unprognostic (1.27e-1)" "unprognostic (4.38e-2)" 7.9 7.1 10.9 85.4 11.4 102.3 8.8 9.6 12.3 6.1 11.1 40.8 87.6 5.1 10.1 8.2 11.9 16.7 5.2 15.4 12.4 9.8 10.4 23.5 114.3 9.7 10.7 10.3 4.7 3.8 10.1 4.9 11.7 7.4 50.9 5.6 36.4 7.3 2.5 6.3 46.4 6.9 10.3 163.9 45.1 10.1 13.5 45.5 10.1 2.7 104.7 45.6 6.4 8.8 17.5 14.8 8.0 15.4 2.8 2.0 11.7 10.5 13.1 14.8 13.2 13.3 12.9 74.5 4.8 5.3 5.6 10.6 25.1 10.0 14.1 567.6 19.6 90.8 15.0 13.9 6.2 21.7 58.7 5.9 8.4 15.3 9.2 12.1 5.5 9.8 97.8 675.0 8.4 12.6 8.4 45.2 165.2 6.1 22.7 9.9 5.4 703.9 14.9 2.6 5.4 7.8 11.5 8.0 8.3 36.9 19.3 29.8 3.6 3.5 2.5 3.1 10.6 1218.7 1160.5 144.1 14.0 19.0 3.7 279.1 8.2 77.7 60.4 9.7 102.3 124.8 165.9 85.6 13.2 73.5 172.4 113.3 195.5 92.7 17.4 15.2 331.9 79.0 10.9 11.4 9.6 12.3 15.4 12.4 9.7 10.7 11.7 10.3 13.5 8.8 2.9 12.8 36.0 1.0 161.6 20.3 9.0 7.1 45.5 2.6 16.2 4.7 3.5 2.8 9.9 3.7 2.1 5.8 46.8 5.7 3.9 3.3 1.9 15.6 1.0 5.3 13.1 49.9 2.3 3.5 9.1 5.1 10.7 3.9 23.4 1.3 4.2 6.3 7.2 11.8 2.2 7.5 18.3 7.5 123.1 1.8 1.8 19.8 94.3 0.0 99.5 2.2 38.1 0.5 1.0 2.0 3.7 4.1 738.8 4.6 4.1 6.8 16.3 2.1 0.0 3.8 6.2 2.2 1.6 15.7 13.8 2.5 97.1 8.6 11.8 3.4 PIM3 ENSG00000198355 "Pim-3 proto-oncogene, serine/threonine kinase" Q86V86 22 49960768-49964072 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 408.4;Syncytiotrophoblasts: 389.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 20.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 163.3;SK-BR-3: 144.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068758 Supported Cytosol NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Cytosol "HPA068758: AB_2686026" "unprognostic (3.67e-2)" "unprognostic (7.69e-3)" "unprognostic (1.07e-1)" "unprognostic (1.11e-1)" "unprognostic (3.67e-2)" "unprognostic (5.83e-2)" "unprognostic (1.48e-2)" "unprognostic (1.13e-2)" "unprognostic (2.71e-2)" "prognostic unfavorable (9.68e-4)" "unprognostic (2.00e-2)" "unprognostic (1.00e-1)" "prognostic favorable (8.09e-4)" "unprognostic (5.59e-3)" "unprognostic (1.71e-1)" "unprognostic (3.92e-3)" "unprognostic (7.27e-3)" 97.8 48.4 25.9 31.3 31.3 114.3 80.2 32.8 38.1 49.2 26.9 55.1 23.8 40.8 12.7 80.8 54.0 25.8 68.7 25.2 32.6 113.3 92.9 107.1 28.2 40.6 36.1 35.7 73.1 21.6 51.3 21.3 38.0 87.3 10.4 3.1 93.5 22.6 112.0 116.4 51.6 9.9 30.3 80.7 118.1 33.9 35.2 19.0 54.9 35.0 13.0 71.0 68.6 39.9 26.8 17.7 11.6 21.9 9.0 6.7 65.5 16.5 26.7 19.4 14.0 29.5 22.3 47.3 20.1 4.6 39.1 22.5 22.3 12.6 6.9 35.8 92.1 19.5 46.3 36.0 41.8 42.5 36.0 12.8 41.0 11.9 20.2 10.5 63.5 31.7 27.0 163.3 5.9 60.6 21.7 76.4 24.2 28.1 27.8 100.3 19.2 57.6 10.6 20.3 41.1 28.6 32.2 144.7 109.2 10.7 19.0 56.4 16.8 12.1 51.5 19.8 27.1 82.2 56.9 41.4 30.1 24.1 33.2 0.0 4.0 0.1 2.2 4.1 2.5 4.3 5.0 4.4 3.1 7.5 4.8 1.9 20.7 1.7 5.2 7.0 5.8 2.7 25.9 31.3 32.8 38.1 25.2 32.6 40.6 36.1 38.0 30.3 35.2 39.9 120.2 64.1 85.9 6.5 107.7 227.3 236.8 79.1 96.8 31.5 99.2 67.3 32.8 121.5 72.8 80.9 2.1 56.9 79.5 57.9 84.1 50.9 5.1 114.2 76.3 167.7 97.7 10.8 10.2 54.5 346.5 69.0 202.3 170.5 69.3 16.8 98.6 45.9 69.7 62.2 6.7 101.7 81.4 41.1 408.4 4.8 32.3 134.8 108.5 6.5 35.8 14.0 11.3 6.6 20.5 71.0 94.6 11.3 95.1 298.4 58.1 88.5 40.9 16.5 26.3 39.4 57.3 26.1 37.7 95.3 204.7 389.9 90.4 11.6 79.0 266.0 PIP5KL1 "bA203J24.5, MGC46424" ENSG00000167103 "Phosphatidylinositol-4-phosphate 5-kinase like 1" Q5T9C9 9 127920881-127930785 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 22.6;Late spermatids: 24.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Karpas-707: 45.5;RPMI-8226: 31.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA056240 Uncertain Supported Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 34: Spermatids - Unknown function" Cytosol "HPA056240: AB_2683075" "unprognostic (2.15e-2)" "unprognostic (3.06e-1)" "unprognostic (1.23e-3)" "unprognostic (8.51e-5)" "unprognostic (1.44e-2)" "unprognostic (4.62e-2)" "unprognostic (1.19e-1)" "unprognostic (6.29e-2)" "unprognostic (5.20e-2)" "unprognostic (5.50e-2)" "unprognostic (2.49e-2)" "unprognostic (1.57e-3)" "unprognostic (9.95e-8)" "unprognostic (1.87e-1)" "unprognostic (7.21e-2)" "unprognostic (6.05e-2)" "unprognostic (1.59e-1)" 0.6 0.2 1.0 0.0 1.0 0.6 1.7 1.6 1.8 2.3 0.2 1.0 0.1 1.3 0.2 3.2 1.7 0.3 0.2 0.9 1.0 1.3 0.2 1.9 0.1 2.1 0.8 0.9 1.3 2.9 3.8 0.6 2.4 3.1 0.0 0.2 3.2 1.4 0.1 3.9 0.5 0.3 0.7 0.6 1.4 2.5 1.3 0.1 1.7 0.0 0.2 1.0 3.6 1.0 0.0 0.7 0.7 0.8 0.8 1.9 4.1 0.8 0.8 0.2 0.2 0.3 5.5 0.5 1.6 3.7 1.6 1.7 0.0 4.1 0.2 0.3 2.7 0.0 1.4 0.1 1.3 0.0 0.2 2.1 2.6 0.6 0.0 1.3 0.0 3.7 0.0 45.5 0.0 4.0 0.0 1.6 0.4 1.7 0.6 0.4 0.1 31.5 0.0 0.1 1.4 2.7 0.3 1.0 0.0 0.4 1.7 2.2 0.6 0.5 1.3 0.9 0.1 4.0 2.8 1.0 8.0 0.6 0.5 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 1.0 1.6 1.8 0.9 1.0 2.1 0.8 2.4 0.7 1.3 1.0 0.5 0.0 9.3 0.3 1.1 2.2 4.7 5.1 8.6 0.7 3.2 4.7 0.5 0.0 2.0 5.5 0.0 0.9 1.5 0.6 1.9 1.4 22.6 2.3 3.5 0.8 0.0 3.2 0.9 1.5 4.4 0.9 7.7 4.1 0.0 1.7 0.4 0.3 0.3 5.0 1.7 0.4 2.0 0.3 0.6 24.6 0.9 0.3 0.0 0.0 0.2 1.9 0.0 0.0 0.1 1.2 0.1 0.4 2.0 2.9 0.1 0.1 7.4 0.8 0.0 1.0 1.3 1.8 2.2 2.3 1.1 3.1 0.9 1.2 0.7 2.1 PIR ENSG00000087842 Pirin O00625 X 15384799-15493564 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 96.1;Syncytiotrophoblasts: 85.6" "Cancer enhanced" "Detected in all" "melanoma: 48.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 292.4;HUVEC TERT2: 683.9;SK-MEL-30: 267.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000697 Approved Supported Cytosol NA NA 35000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 27: Brain & Skin - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA000697: AB_1079621" "unprognostic (3.46e-3)" "prognostic favorable (2.78e-4)" "unprognostic (4.26e-2)" "unprognostic (5.62e-3)" "unprognostic (4.16e-3)" "unprognostic (2.09e-2)" "unprognostic (6.70e-3)" "unprognostic (1.65e-1)" "unprognostic (1.08e-1)" "prognostic favorable (4.94e-4)" "unprognostic (3.78e-2)" "unprognostic (1.92e-1)" "prognostic unfavorable (6.11e-7)" "unprognostic (1.99e-2)" "unprognostic (8.90e-2)" "unprognostic (1.03e-1)" "unprognostic (1.44e-1)" 19.1 19.9 20.2 5.2 23.7 5.7 15.4 23.5 24.3 12.4 21.2 10.0 6.5 11.7 15.3 29.6 13.3 11.4 17.3 18.7 22.9 11.4 21.0 15.4 2.7 23.0 22.6 13.1 3.3 4.9 11.3 10.5 22.8 10.1 6.7 7.9 10.3 14.2 14.7 11.9 8.6 10.4 22.5 20.1 11.9 6.2 22.5 6.2 15.7 6.4 7.1 30.4 17.4 25.7 14.3 76.6 45.0 66.3 26.1 29.0 14.4 4.2 26.5 11.0 24.5 21.5 118.9 0.0 147.2 12.3 292.4 96.7 52.8 21.3 4.0 0.0 11.6 8.4 80.7 63.9 33.4 4.4 29.8 8.3 72.3 41.9 14.4 19.2 683.9 0.0 6.4 19.2 9.4 29.8 3.3 4.1 48.4 62.1 47.7 0.0 8.9 37.9 22.2 136.0 17.2 47.5 36.7 20.5 267.9 76.8 42.4 26.7 43.2 5.9 11.0 28.5 8.7 9.1 39.6 0.3 28.6 15.8 59.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 20.2 23.7 23.5 24.3 18.7 22.9 23.0 22.6 22.8 22.5 22.5 25.7 24.5 0.0 4.1 0.0 1.1 8.7 24.3 48.4 10.8 2.8 4.2 4.8 5.8 10.0 19.4 1.8 0.0 96.1 0.0 4.8 9.8 5.9 0.6 59.6 3.8 40.3 11.3 11.6 0.2 2.5 12.8 15.6 15.8 20.0 0.0 21.7 22.9 24.0 22.0 20.2 0.2 3.4 38.7 6.4 3.4 4.0 37.6 4.1 40.9 0.0 11.9 30.8 0.0 0.0 0.0 3.4 1.7 28.6 3.6 18.1 5.9 12.0 38.0 4.8 13.1 8.4 11.3 0.6 3.5 34.5 12.6 85.6 0.6 56.2 4.3 50.9 PKLR ENSG00000143627 "Pyruvate kinase L/R" P30613 1 155289293-155301438 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 19.6;kidney: 25.1;liver: 92.5" "Cell type enhanced" "Detected in some" "Early spermatids: 9.3;Erythroid cells: 22.1;Hepatocytes: 16.3;Late spermatids: 23.0;Proximal enterocytes: 14.8;Proximal tubular cells: 48.9" "Cancer enriched" "Detected in some" 9 "liver cancer: 56.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "K-562: 107.8" "Region enhanced" "Detected in single" "basal ganglia: 1.6" "Not detected" "Not detected" "HPA006653, CAB034376, CAB034378" Enhanced Approved Cytosol No NA 5200000 "Cluster 85: Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "CAB034376: AB_2163671, CAB034378: AB_2252321, HPA006653: AB_2667632" "unprognostic (9.16e-2)" "unprognostic (1.22e-1)" "unprognostic (2.22e-1)" "unprognostic (5.98e-2)" "unprognostic (2.62e-1)" "unprognostic (7.86e-4)" "unprognostic (1.53e-2)" "unprognostic (1.08e-1)" "unprognostic (8.79e-2)" "unprognostic (1.89e-1)" "unprognostic (4.07e-1)" "unprognostic (4.53e-2)" "unprognostic (1.96e-2)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (1.32e-1)" "unprognostic (6.21e-3)" 0.0 0.0 0.0 0.0 0.1 19.6 0.0 0.7 0.1 0.0 0.0 0.4 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 25.1 92.5 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 1.2 7.2 0.0 0.0 0.1 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 11.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.1 0.0 0.5 0.2 0.2 0.3 0.0 0.4 0.0 0.1 0.0 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.4 1.5 0.0 1.8 0.0 0.0 0.0 0.6 0.0 0.0 9.3 0.2 0.3 0.1 0.0 22.1 1.2 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.7 16.3 0.2 0.0 1.2 0.9 0.0 0.0 0.0 23.0 0.0 0.3 0.0 1.0 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 14.8 48.9 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 PKM "OIP3, PK3, PKM2, THBP1" ENSG00000067225 "Pyruvate kinase M1/2" P14618 15 72199029-72231822 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycolysis, Translation regulation" "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 4207.6;tongue: 2900.8" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 2065.2;Late spermatids: 1763.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019421, HPA029501" Uncertain Enhanced Cytosol No No 310000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "CAB019421: AB_2252325, HPA029501: AB_10602118" "unprognostic (8.73e-3)" "unprognostic (4.63e-3)" "unprognostic (1.68e-2)" "unprognostic (3.09e-1)" "unprognostic (6.51e-2)" "prognostic unfavorable (1.30e-4)" "prognostic unfavorable (2.74e-6)" "prognostic unfavorable (2.85e-4)" "unprognostic (9.51e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (5.17e-5)" "unprognostic (3.16e-1)" "unprognostic (3.22e-1)" "unprognostic (7.85e-2)" "unprognostic (3.17e-2)" "unprognostic (1.44e-1)" "unprognostic (1.25e-2)" 190.5 600.9 539.0 341.4 552.3 439.0 190.5 586.8 629.9 406.8 755.0 225.0 170.8 202.8 205.7 658.3 240.0 212.0 779.6 549.1 561.6 549.5 32.2 236.9 284.1 640.0 559.1 169.4 112.6 269.6 224.1 168.6 636.2 252.6 206.2 1266.7 389.8 291.6 4207.6 350.5 218.0 298.9 522.3 239.2 228.6 235.1 677.1 203.5 174.6 2900.8 429.2 578.5 374.9 530.6 1584.6 3937.1 788.9 938.8 914.3 1009.4 638.7 1684.6 3878.2 2619.1 2623.6 1094.4 1931.2 1184.5 1627.3 3157.6 1937.8 2253.9 2480.9 3383.2 2051.7 2134.0 1126.5 727.7 1809.1 929.7 637.1 955.2 1525.1 926.4 1559.2 2025.1 810.9 3403.0 1558.6 587.3 182.8 933.3 4267.0 965.1 359.4 419.6 966.2 2438.6 1433.3 1046.5 2560.0 2301.7 3557.2 1973.8 804.4 871.5 2226.3 1344.7 1755.4 1291.4 932.0 675.7 1247.3 3003.7 1622.0 2928.7 3110.3 1170.0 1762.1 1037.2 3720.5 1534.4 3002.3 131.9 836.3 138.6 192.6 466.7 187.9 205.2 254.1 190.4 685.6 142.9 215.8 162.5 100.7 108.4 380.1 140.5 334.0 1261.7 539.0 552.3 586.8 629.9 549.1 561.6 640.0 559.1 636.2 522.3 677.1 530.6 95.9 118.6 88.1 107.7 169.6 565.5 708.9 2065.2 307.9 480.7 157.8 174.7 313.2 87.2 759.4 829.4 369.1 566.1 100.2 358.9 802.2 1395.6 315.0 169.2 77.3 207.7 282.2 44.8 90.2 597.0 1416.7 220.1 138.1 188.0 206.7 144.0 73.2 4.3 750.0 1065.0 97.6 166.8 925.7 297.7 532.9 1763.1 157.2 558.8 355.8 38.4 1255.0 784.1 78.2 53.3 33.4 1213.2 264.5 268.1 209.9 431.4 389.1 208.7 396.9 708.6 124.9 160.9 398.2 43.4 98.6 341.6 389.0 575.7 192.7 157.4 380.7 860.7 PLA2G4C cPLA2-gamma ENSG00000105499 "Phospholipase A2 group IVC" Q9UP65 19 48047843-48110817 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction, Lipid metabolism, Phospholipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 78.8;skeletal muscle: 66.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 77.1;Cone photoreceptor cells: 66.7;Muller glia cells: 57.1;Oligodendrocytes: 137.1;Rod photoreceptor cells: 153.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 5.7" "Group enriched" "Detected in many" 4 "B-cells: 4.0;monocytes: 5.7" "Cell line enhanced" "Detected in many" "HHSteC: 13.1;TIME: 19.4" "Not detected" "Not detected" HPA043083 Approved Approved Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol "HPA043083: AB_10795714" "unprognostic (1.27e-1)" "unprognostic (3.88e-2)" "unprognostic (4.18e-2)" "unprognostic (2.82e-2)" "unprognostic (7.37e-2)" "unprognostic (1.62e-2)" "unprognostic (1.33e-1)" "unprognostic (6.53e-2)" "unprognostic (8.30e-2)" "unprognostic (1.94e-1)" "unprognostic (5.11e-3)" "unprognostic (1.90e-1)" "unprognostic (4.66e-2)" "unprognostic (9.45e-2)" "unprognostic (2.28e-3)" "unprognostic (1.87e-1)" "unprognostic (9.01e-2)" 5.1 17.3 13.8 5.5 23.8 0.3 4.3 20.8 20.5 4.6 4.5 6.5 6.3 8.6 3.0 4.3 5.1 5.8 25.1 14.1 18.2 6.1 4.7 8.0 10.2 24.8 23.5 1.7 4.9 12.8 6.6 5.1 26.7 6.8 3.3 78.8 4.1 8.0 66.7 6.4 8.5 10.3 14.3 11.2 3.3 2.8 21.1 4.7 4.9 41.2 5.6 5.1 2.6 41.5 0.7 1.3 0.0 0.3 5.7 3.0 0.1 1.3 8.5 1.4 3.4 0.0 2.1 0.0 1.8 3.7 2.7 0.3 0.0 0.2 2.2 0.9 0.2 0.0 0.5 1.3 13.1 0.0 1.9 0.6 0.3 0.7 5.7 2.6 4.9 0.1 0.0 8.0 2.2 2.2 0.1 0.2 0.1 1.0 0.1 0.1 2.0 0.8 2.7 0.6 0.9 0.1 1.5 2.9 7.1 4.3 0.8 2.2 19.4 2.2 0.8 2.8 1.0 0.5 1.8 0.2 1.9 0.0 4.8 0.0 2.1 0.0 0.1 5.7 0.4 4.0 0.5 0.0 1.2 0.9 0.0 0.0 0.0 1.1 1.4 0.8 0.1 1.4 13.8 23.8 20.8 20.5 14.1 18.2 24.8 23.5 26.7 14.3 21.1 41.5 7.2 3.2 1.7 30.7 2.4 2.8 1.0 1.5 1.2 77.1 2.4 2.9 35.3 5.7 0.5 0.0 66.7 0.2 0.6 1.2 1.9 13.0 0.3 0.5 4.6 14.3 0.0 0.0 31.6 2.9 0.2 7.4 1.1 0.7 0.0 0.1 4.6 2.0 5.6 33.7 34.7 1.6 18.3 1.2 11.1 0.2 0.6 4.9 7.2 15.0 3.1 57.1 1.0 25.1 137.1 2.7 1.4 7.9 0.7 2.5 5.7 5.2 0.2 153.8 13.1 18.0 9.9 0.9 1.0 0.2 3.0 0.1 1.1 1.6 0.3 0.4 PLA2R1 "CLEC13C, PLA2-R, PLA2G1R, PLA2IR" ENSG00000153246 "Phospholipase A2 receptor 1" Q13018 2 159932006-160062615 "Predicted membrane proteins, Predicted secreted proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 39.1;thyroid gland: 41.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 33.1;Excitatory neurons: 34.6;Inhibitory neurons: 43.5;Muller glia cells: 33.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 9.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 14.5;ASC TERT1: 19.5;BJ hTERT+: 16.2;hTERT-RPE1: 26.3;TIME: 47.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB068217, CAB068218" Approved Approved Cytosol "Secreted to blood" NA NA 960000 "Cluster 1: Thyroid gland - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "CAB068217: AB_2665660, CAB068218: AB_2665661" "unprognostic (2.04e-1)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.39e-2)" "unprognostic (4.91e-3)" "unprognostic (6.01e-2)" "unprognostic (9.71e-2)" "unprognostic (1.09e-1)" "unprognostic (1.40e-2)" "unprognostic (9.38e-3)" "unprognostic (4.30e-3)" "unprognostic (2.82e-1)" "unprognostic (2.14e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (2.62e-1)" "unprognostic (6.58e-2)" "unprognostic (2.02e-1)" 4.7 2.9 0.7 1.4 0.8 0.0 14.9 9.7 2.2 6.9 1.7 3.1 3.9 8.8 2.9 4.7 5.4 9.3 2.5 0.5 1.5 20.8 1.4 2.6 1.9 2.0 2.7 10.8 0.6 19.7 2.2 3.8 2.1 3.1 3.2 5.6 39.1 2.9 0.5 10.9 6.1 6.9 1.4 5.1 1.6 1.0 2.5 0.6 41.9 1.3 2.7 3.9 6.0 1.0 0.2 1.6 0.6 0.0 14.5 19.5 0.1 6.8 16.2 1.3 1.8 0.0 3.4 0.0 0.4 7.2 1.4 3.3 0.1 5.0 1.4 0.0 0.0 0.0 11.8 0.0 1.2 0.0 0.0 7.9 5.4 1.9 2.1 26.3 9.3 0.0 0.0 0.0 2.3 0.1 0.0 0.0 0.2 0.1 2.6 0.0 0.0 0.0 1.4 0.7 0.0 0.0 11.8 2.2 0.0 1.7 2.6 0.2 47.3 0.0 0.8 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.7 0.8 9.7 2.2 0.5 1.5 2.0 2.7 2.1 1.4 2.5 1.0 11.1 6.4 2.8 20.9 0.1 9.4 2.7 18.1 21.6 2.7 22.1 14.5 4.1 5.7 11.3 33.1 0.0 7.3 0.5 1.7 0.0 0.6 0.1 5.6 22.0 4.0 1.2 0.0 34.6 2.0 1.3 14.8 0.0 9.4 1.3 9.6 8.6 0.0 0.6 16.8 43.5 7.2 4.1 0.0 2.1 1.4 16.1 0.5 7.2 25.3 0.0 33.5 0.0 5.5 1.8 5.1 11.3 16.6 0.1 2.6 15.6 2.3 8.1 1.4 6.6 3.4 4.8 0.1 1.0 9.3 5.4 1.5 0.6 6.3 7.5 3.0 PLAC8 "C15, onzin" ENSG00000145287 "Placenta associated 8" Q9NZF1 4 83090048-83137075 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 365.9;esophagus: 92.0;intestine: 236.0;lymphoid tissue: 155.1;stomach 1: 117.5" "Cell type enhanced" "Detected in many" "dendritic cells: 1118.2;Distal enterocytes: 1514.4;Extravillous trophoblasts: 572.2;NK-cells: 1103.0;Paneth cells: 865.7;Respiratory ciliated cells: 549.6" "Cancer enhanced" "Detected in many" "stomach cancer: 17.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 2310.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 183.2;CAPAN-2: 510.7;HL-60: 329.1;NB-4: 160.1;RPMI-8226: 238.2;THP-1: 187.8;U-937: 149.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040465, HPA077912" Enhanced Approved Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA040465: AB_10794875, HPA077912: AB_2686870" "unprognostic (6.82e-5)" "prognostic favorable (3.03e-4)" "unprognostic (3.29e-2)" "unprognostic (4.64e-2)" "unprognostic (2.05e-1)" "unprognostic (4.86e-2)" "unprognostic (1.14e-1)" "unprognostic (1.94e-3)" "unprognostic (1.20e-1)" "unprognostic (1.77e-1)" "unprognostic (7.44e-3)" "unprognostic (1.65e-1)" "unprognostic (1.66e-7)" "unprognostic (3.89e-2)" "unprognostic (2.85e-3)" "unprognostic (1.32e-1)" "unprognostic (1.12e-1)" 9.2 2.0 1.8 81.3 2.0 365.9 3.8 2.8 2.4 32.8 1.4 236.0 78.9 2.7 1.2 92.0 18.7 6.5 2.8 1.5 1.7 2.6 35.4 41.2 93.8 7.8 2.7 1.0 1.6 0.5 2.0 33.7 5.5 3.7 163.3 1.1 6.6 2.3 2.0 1.0 88.5 18.5 2.3 155.1 117.5 0.8 2.4 40.5 2.6 0.8 137.5 11.0 5.8 3.7 183.2 1.3 0.5 1.1 0.0 0.2 28.6 4.6 1.1 11.1 13.7 3.5 510.7 30.7 1.5 52.3 17.0 18.7 3.2 1.4 41.6 0.2 0.6 0.8 33.4 15.2 1.8 329.1 1.7 0.9 3.6 1.8 2.4 0.3 0.8 16.0 0.4 2.6 29.5 0.8 62.6 160.1 1.0 14.4 0.9 8.0 10.6 238.2 0.9 5.4 25.8 0.5 1.2 29.1 0.6 9.0 1.6 187.8 1.3 1.1 31.7 0.9 0.9 1.8 0.4 81.7 2.3 149.7 0.2 49.2 139.2 95.9 392.1 635.8 299.4 523.8 185.1 229.2 129.5 481.1 225.9 263.4 29.7 1053.3 358.9 2310.7 13.8 577.1 1.8 2.0 2.8 2.4 1.5 1.7 7.8 2.7 5.5 2.3 2.4 3.7 4.3 195.5 39.2 0.3 247.4 0.4 1.7 77.3 0.0 0.3 0.9 1.4 0.5 2.8 119.1 0.0 0.0 18.5 1118.2 1514.4 0.0 0.3 0.5 45.6 1.1 95.0 86.8 58.4 0.1 3.6 572.2 3.1 119.8 2.9 26.6 0.6 141.0 8.4 21.7 1.7 0.1 231.2 67.1 384.5 7.4 0.6 0.0 213.3 7.2 1.0 157.3 1.2 1103.0 0.0 0.2 99.0 865.7 0.0 35.7 1.1 374.4 1.4 549.6 0.3 6.6 0.7 8.0 0.2 0.8 10.1 0.1 14.2 150.6 0.1 104.2 9.0 PLCE1 "KIAA1516, NPHS3, PLCE" ENSG00000138193 "Phospholipase C epsilon 1" Q9P212 10 93993931-94332823 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Guanine-nucleotide releasing factor, Hydrolase, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 70.5;Astrocytes: 69.5;Distal enterocytes: 79.6;Inhibitory neurons: 83.9;Muller glia cells: 82.7;Oligodendrocyte precursor cells: 123.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RT4: 10.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015597, HPA015598" Enhanced Supported Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA015597: AB_1855321, HPA015598: AB_1855322" "unprognostic (4.73e-2)" "unprognostic (1.16e-1)" "unprognostic (4.03e-2)" "unprognostic (3.59e-3)" "unprognostic (3.01e-1)" "unprognostic (2.96e-1)" "unprognostic (1.73e-2)" "unprognostic (4.76e-3)" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (3.26e-3)" "unprognostic (3.56e-1)" "unprognostic (3.92e-2)" "unprognostic (3.54e-2)" "unprognostic (4.30e-2)" 3.8 2.6 4.5 2.8 4.1 0.2 2.7 3.1 5.6 8.0 7.0 12.6 4.0 9.0 5.3 1.7 4.4 2.5 12.4 3.9 4.7 8.4 0.7 7.3 0.7 3.9 4.8 3.9 14.7 0.8 4.4 2.9 4.0 3.8 7.5 7.3 2.3 5.4 4.1 1.1 5.2 4.2 3.2 6.2 8.3 2.0 5.4 0.5 9.8 6.3 0.6 5.6 5.6 4.2 4.0 6.7 1.8 1.1 0.7 3.2 1.9 2.8 0.6 0.3 0.4 5.3 1.3 0.8 1.3 2.3 1.3 2.6 2.2 0.4 0.6 0.4 2.3 0.5 4.0 0.5 0.0 0.9 0.3 1.8 0.0 1.1 0.0 6.8 0.0 0.4 0.5 0.3 4.2 0.3 0.8 0.9 0.7 7.9 5.0 0.1 3.9 0.2 0.2 10.3 0.9 1.5 3.3 3.6 0.7 4.1 3.5 0.6 0.6 3.0 5.9 2.0 4.4 0.6 0.3 0.4 3.5 1.1 2.2 0.1 0.1 0.0 0.3 0.2 0.2 0.5 0.3 0.2 0.1 0.7 0.5 0.4 0.1 0.2 0.2 0.2 0.1 0.1 4.5 4.1 3.1 5.6 3.9 4.7 3.9 4.8 4.0 3.2 5.4 4.2 8.2 70.5 5.4 69.5 7.0 8.2 9.7 6.8 2.2 12.2 3.6 3.6 34.7 4.3 12.3 0.0 0.0 3.7 2.9 79.6 1.9 1.1 20.7 26.7 18.4 9.7 1.8 0.0 3.1 6.4 2.5 15.3 29.6 10.6 0.0 7.2 4.2 1.6 0.7 6.7 83.9 9.7 4.1 2.4 5.2 5.3 12.2 1.3 7.2 5.6 1.2 82.7 4.1 123.1 2.4 4.2 54.8 23.3 0.9 7.5 11.0 2.5 10.6 18.7 6.6 30.8 37.7 3.7 8.0 1.7 7.4 1.9 4.3 3.7 41.1 10.5 PLCG1 "NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1" ENSG00000124181 "Phospholipase C gamma 1" P19174 20 41136960-41196801 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction, Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 69.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "gdT-cell: 4.7;MAIT T-cell: 6.4;memory CD4 T-cell: 4.1;memory CD8 T-cell: 3.9;naive CD4 T-cell: 4.3;naive CD8 T-cell: 4.3;NK-cell: 3.4;T-reg: 3.8" "Group enriched" "Detected in many" 9 "NK-cells: 3.4;T-cells: 6.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004277, HPA036681, HPA036682" Approved Enhanced Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 58: T-cells - T-cell receptor" Cytosol "CAB004277: AB_628119, HPA036681: AB_2675245, HPA036682: AB_2675246" "unprognostic (2.77e-1)" "unprognostic (1.35e-1)" "unprognostic (1.65e-1)" "unprognostic (4.31e-2)" "unprognostic (5.82e-2)" "unprognostic (2.09e-2)" "unprognostic (4.45e-3)" "unprognostic (1.25e-2)" "unprognostic (2.29e-2)" "unprognostic (1.16e-1)" "prognostic favorable (4.72e-4)" "unprognostic (3.32e-1)" "unprognostic (2.73e-3)" "unprognostic (1.82e-1)" "unprognostic (2.65e-1)" "unprognostic (9.27e-2)" "unprognostic (2.79e-2)" 33.3 22.4 36.2 21.7 37.3 10.0 31.8 43.8 41.3 42.5 27.8 25.2 17.8 36.1 13.7 18.9 31.9 19.9 31.9 35.6 32.9 23.2 9.7 32.4 36.4 34.8 36.2 42.6 11.4 13.3 21.6 23.8 34.2 30.2 13.7 10.9 20.2 20.5 18.5 31.5 28.8 22.9 32.0 30.0 19.4 26.3 39.5 60.5 45.0 20.3 24.0 30.4 32.0 38.6 16.6 20.8 97.2 71.6 38.0 26.5 30.9 26.7 34.1 52.4 44.3 50.1 5.4 37.0 31.9 29.1 55.0 30.2 42.7 47.8 30.4 10.5 22.7 2.6 36.4 59.6 28.9 14.7 9.7 34.1 26.3 38.8 30.0 47.2 59.4 77.3 28.0 23.6 48.0 123.8 90.7 11.5 36.2 21.3 37.6 71.1 70.8 18.2 28.7 30.1 34.4 65.7 47.8 22.1 48.4 54.1 25.8 17.0 64.6 124.4 40.3 40.2 32.9 26.1 12.4 30.3 29.7 15.6 52.9 0.0 0.0 0.0 4.7 0.0 6.4 0.2 4.1 3.9 0.0 0.5 4.3 4.3 0.0 3.4 0.0 0.0 3.8 3.0 36.2 37.3 43.8 41.3 35.6 32.9 34.8 36.2 34.2 32.0 39.5 38.6 33.4 16.0 7.0 69.2 5.1 5.6 1.8 5.3 14.8 4.3 4.7 5.8 9.6 1.5 3.8 3.7 10.4 1.9 7.4 9.4 0.0 3.3 7.0 5.4 16.9 24.2 1.8 2.1 9.7 1.6 2.0 11.5 10.2 10.3 1.3 19.8 11.7 3.1 4.0 3.3 9.1 9.5 4.1 2.9 4.3 7.2 15.2 1.7 3.6 16.9 1.2 6.7 2.1 13.0 16.4 3.3 4.8 18.4 6.3 2.3 7.8 3.0 1.8 5.1 13.1 8.5 10.2 15.9 13.0 6.1 7.0 0.8 17.0 5.7 6.4 0.9 PLCXD1 FLJ11323 ENSG00000182378 "Phosphatidylinositol specific phospholipase C X domain containing 1" Q9NUJ7 X 276322-303356 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 34.7;Distal enterocytes: 34.2;Gastric mucus-secreting cells: 33.1;Paneth cells: 40.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 110.4;HEL: 172.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA007721 Approved Approved Cytosol NA Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 36: HEL - Hemostasis" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA007721: AB_1079630" "unprognostic (2.73e-2)" "unprognostic (5.67e-2)" "unprognostic (4.57e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (3.80e-2)" "prognostic favorable (2.50e-4)" "unprognostic (1.47e-3)" "unprognostic (7.92e-2)" "unprognostic (1.72e-2)" "unprognostic (4.80e-2)" "unprognostic (7.25e-2)" "unprognostic (1.11e-3)" "prognostic unfavorable (7.82e-14)" "unprognostic (6.01e-2)" "unprognostic (1.95e-1)" "unprognostic (3.59e-2)" "unprognostic (1.78e-1)" 14.7 4.1 4.6 9.4 8.8 32.9 9.7 13.0 19.2 10.0 0.0 8.2 8.6 5.6 1.4 17.5 9.1 8.8 5.6 4.4 0.0 5.7 10.1 7.4 17.3 3.4 1.5 12.8 7.5 3.2 7.7 7.8 4.4 7.5 5.7 6.0 11.4 3.7 8.4 18.7 12.5 2.7 0.5 17.5 26.9 6.7 4.0 8.9 10.4 2.7 9.0 6.1 9.7 13.4 28.4 110.4 25.7 38.8 5.0 3.9 20.4 24.4 2.9 12.8 12.4 40.6 29.1 34.8 17.9 10.7 19.0 8.5 6.3 15.9 6.7 21.2 46.2 172.6 36.1 59.7 15.6 17.4 63.1 20.1 1.9 47.0 4.9 8.6 9.7 57.2 44.0 18.7 9.2 8.2 52.3 24.2 57.8 7.1 19.2 29.1 13.3 53.9 3.9 12.9 25.9 15.0 24.6 14.4 21.1 17.5 27.6 22.0 7.2 17.1 28.2 18.5 26.9 6.3 17.9 86.4 11.0 44.4 18.2 3.7 2.7 5.4 1.9 6.0 2.7 1.6 1.4 2.4 2.0 5.6 1.8 1.9 3.3 1.2 9.0 2.1 3.2 2.3 4.6 8.8 13.0 19.2 4.4 0.0 3.4 1.5 4.4 0.5 4.0 13.4 15.8 9.6 34.7 5.5 4.1 6.9 13.6 3.9 2.2 7.4 4.7 3.6 6.5 10.0 2.8 0.0 2.1 10.1 4.9 34.2 0.0 6.3 0.9 1.6 3.4 6.1 3.0 9.9 5.3 1.8 11.3 6.1 33.1 3.2 3.8 32.1 4.6 6.9 5.5 8.4 6.1 11.2 0.0 7.3 9.8 0.9 2.5 11.9 0.0 5.6 3.7 2.3 9.2 0.5 5.7 18.8 40.9 3.8 2.7 5.3 3.0 1.7 1.3 7.1 13.1 6.5 7.9 8.4 15.9 4.2 8.7 27.0 3.8 2.8 9.4 8.0 PLPBP PROSC ENSG00000147471 "Pyridoxal phosphate binding protein" O94903 8 37762595-37779768 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 101.8;Exocrine glandular cells: 49.8;Hofbauer cells: 47.3;Proximal tubular cells: 82.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017033, HPA023646, HPA023733" Approved Enhanced Cytosol NA NA 34000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Cytosol "CAB017033: , HPA023646: AB_1855741, HPA023733: AB_1855742" "unprognostic (1.55e-2)" "unprognostic (2.17e-2)" "unprognostic (2.14e-2)" "unprognostic (2.95e-2)" "unprognostic (1.34e-1)" "unprognostic (2.35e-2)" "unprognostic (2.36e-1)" "unprognostic (7.78e-3)" "unprognostic (1.80e-1)" "unprognostic (4.28e-2)" "unprognostic (2.83e-2)" "unprognostic (2.59e-2)" "unprognostic (9.41e-3)" "unprognostic (3.16e-2)" "unprognostic (3.99e-2)" "unprognostic (2.90e-1)" "unprognostic (7.85e-2)" 34.2 23.1 22.2 21.2 24.3 14.6 23.3 25.3 27.1 22.1 26.8 47.2 34.5 19.2 23.3 20.2 27.5 19.1 39.2 24.0 25.0 58.5 78.2 25.7 25.0 22.8 24.9 24.7 40.3 37.4 16.2 20.1 23.7 20.2 37.9 10.9 28.3 27.8 46.4 17.0 37.3 25.9 23.7 25.0 33.5 8.4 24.5 27.4 31.8 42.1 29.0 22.9 16.1 28.6 50.3 45.4 35.1 32.0 25.9 31.1 31.6 55.2 45.8 34.7 38.9 51.6 24.3 58.4 61.9 39.9 55.5 41.4 65.4 52.5 56.6 49.9 34.3 79.4 16.4 51.7 51.6 36.8 52.5 22.9 49.8 33.0 52.0 37.6 52.3 78.3 42.8 42.1 28.7 34.8 116.4 32.4 43.0 92.8 41.9 73.6 46.6 34.8 56.5 60.0 21.5 25.1 45.4 20.0 56.8 25.4 44.2 48.6 52.1 19.1 60.7 69.8 38.1 43.3 90.9 43.0 27.4 51.8 35.0 164.3 109.6 136.1 85.6 130.0 90.0 77.8 87.8 83.6 115.2 61.9 77.0 74.3 46.9 75.9 147.4 66.5 116.7 110.2 22.2 24.3 25.3 27.1 24.0 25.0 22.8 24.9 23.7 23.7 24.5 28.6 35.9 9.6 26.5 0.0 6.7 0.0 0.0 0.0 0.0 0.0 27.8 23.0 0.0 0.0 8.1 31.3 0.0 21.2 20.0 0.0 101.8 38.2 0.0 12.8 20.7 13.5 0.0 0.0 0.0 49.8 31.6 13.9 0.0 19.6 12.6 14.8 0.0 0.0 47.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.9 0.0 0.0 11.9 0.0 0.0 0.0 0.0 33.2 0.0 0.0 1.8 0.0 0.0 82.2 13.8 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 12.9 9.8 17.1 0.0 0.0 PMM1 Sec53 ENSG00000100417 "Phosphomannomutase 1" Q92871 22 41576900-41589871 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 176.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030712, HPA074950" Uncertain Supported Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 45: Enterocytes - Digestion" Cytosol "HPA030712: AB_10669600, HPA074950: " "unprognostic (2.66e-1)" "prognostic favorable (5.92e-4)" "unprognostic (3.25e-2)" "prognostic favorable (6.09e-6)" "unprognostic (1.25e-1)" "unprognostic (2.85e-2)" "unprognostic (1.01e-2)" "unprognostic (1.95e-2)" "unprognostic (2.24e-3)" "unprognostic (1.78e-1)" "prognostic favorable (2.05e-4)" "unprognostic (6.56e-3)" "unprognostic (5.76e-3)" "unprognostic (2.78e-2)" "unprognostic (1.72e-1)" "unprognostic (1.40e-2)" "unprognostic (2.70e-1)" 47.0 51.7 49.0 12.0 50.4 26.2 39.0 47.0 65.0 34.4 41.2 33.6 37.7 26.9 19.2 73.7 34.7 18.8 26.5 49.5 52.1 59.4 64.2 33.8 17.5 46.9 47.2 48.1 45.0 15.4 19.5 14.2 51.2 26.5 20.3 13.6 23.3 20.2 16.2 33.2 33.8 19.9 47.8 13.7 65.7 32.6 49.8 14.3 13.8 11.4 16.8 31.7 28.0 49.7 16.0 29.0 19.6 42.5 54.3 84.0 23.0 61.7 69.8 56.0 61.0 23.0 15.3 14.9 20.3 74.4 40.0 23.4 25.8 40.0 31.1 31.2 38.6 3.8 34.8 49.2 85.8 22.6 23.8 70.4 38.2 58.3 24.2 61.9 9.3 23.8 16.9 51.9 76.5 42.0 17.1 32.5 6.2 75.1 38.2 13.1 20.7 30.7 24.0 17.1 5.8 11.2 50.5 18.1 75.2 15.2 20.3 24.4 7.5 63.2 34.3 59.4 32.8 33.2 34.0 24.3 70.3 18.8 38.7 21.0 22.0 44.8 27.7 18.5 22.3 17.8 27.6 22.8 23.2 20.5 29.4 21.1 28.8 13.4 22.9 9.2 49.4 18.8 49.0 50.4 47.0 65.0 49.5 52.1 46.9 47.2 51.2 47.8 49.8 49.7 7.8 35.3 106.4 16.3 15.0 14.8 10.2 22.5 20.5 16.7 22.8 29.3 12.4 82.9 25.8 35.0 6.2 57.1 10.0 104.8 107.6 31.8 17.1 77.7 34.2 6.9 48.7 19.3 14.9 11.0 91.1 33.3 36.2 51.4 3.8 60.9 8.9 83.5 34.5 28.6 10.9 58.1 14.2 14.4 13.5 15.3 28.0 16.3 44.4 3.7 21.9 67.1 16.5 4.0 7.1 10.8 117.0 30.5 17.7 8.5 176.1 138.5 34.8 22.6 39.5 18.9 36.9 72.6 10.9 23.1 14.1 65.3 21.0 37.9 55.3 8.2 PNP "NP, PUNP" ENSG00000198805 "Purine nucleoside phosphorylase" P00491 14 20468954-20477089 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine salvage" "Glycosyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 333.9;epididymis: 594.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 360.6;Erythroid cells: 227.3;Syncytiotrophoblasts: 646.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HL-60: 531.3;U-937: 593.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001625 Enhanced Supported Cytosol NA NA 58000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA001625: AB_1854577" "unprognostic (1.20e-3)" "unprognostic (2.68e-2)" "unprognostic (1.04e-2)" "unprognostic (1.70e-1)" "unprognostic (3.10e-1)" "unprognostic (7.06e-2)" "prognostic unfavorable (4.43e-4)" "unprognostic (4.94e-3)" "unprognostic (3.87e-2)" "unprognostic (7.45e-2)" "unprognostic (1.85e-2)" "unprognostic (2.21e-1)" "prognostic favorable (2.24e-4)" "unprognostic (1.69e-1)" "unprognostic (7.54e-2)" "unprognostic (2.46e-1)" "unprognostic (1.64e-3)" 78.6 24.8 16.1 46.8 16.6 333.9 34.6 22.6 22.7 25.3 18.9 52.2 120.3 14.2 594.8 87.4 18.2 56.8 29.0 17.7 19.6 206.8 98.0 48.6 46.7 20.3 18.1 5.0 23.2 32.0 19.8 132.6 20.1 15.0 61.8 27.1 22.6 27.4 7.3 29.6 60.3 38.7 23.1 44.5 50.6 7.4 21.1 33.5 17.8 10.0 64.4 100.4 41.5 20.1 86.1 113.4 24.0 53.9 26.0 21.0 71.8 85.2 40.3 68.2 67.0 66.1 76.5 227.1 96.8 45.5 81.5 89.9 125.2 159.8 89.5 75.0 109.6 189.1 89.9 109.3 24.2 531.3 94.7 14.4 57.4 206.0 91.0 37.8 295.9 141.0 95.4 137.4 86.7 79.1 157.6 311.3 67.5 215.7 186.1 130.2 35.9 88.3 243.7 79.6 101.9 22.6 163.4 205.0 13.2 32.6 75.5 92.5 240.0 46.1 62.6 105.1 148.4 63.1 113.3 258.9 39.3 593.0 4.6 12.0 30.6 10.3 39.8 27.3 73.6 25.7 44.2 45.0 48.1 28.8 27.6 35.9 3.7 38.5 26.6 27.3 16.7 31.1 16.1 16.6 22.6 22.7 17.7 19.6 20.3 18.1 20.1 23.1 21.1 20.1 149.6 0.0 23.5 5.9 50.3 84.6 67.4 12.6 112.7 4.7 56.3 62.6 3.5 27.1 13.4 82.8 14.6 360.6 45.2 61.1 39.2 43.2 1.3 36.0 12.7 139.4 46.4 227.3 0.6 51.5 41.8 32.4 106.5 65.3 57.7 5.0 24.3 30.6 70.9 16.8 1.1 51.3 18.3 18.1 58.4 0.8 0.3 83.3 30.2 3.7 13.2 78.8 29.9 3.0 0.9 130.8 83.9 0.7 88.6 27.5 41.2 118.9 10.5 18.1 0.0 23.9 41.3 0.4 0.7 114.7 63.9 646.2 62.3 3.1 51.4 77.1 PPCDC "FLJ14585, MDS018" ENSG00000138621 "Phosphopantothenoylcysteine decarboxylase" Q96CD2 15 75023586-75117462 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Coenzyme A biosynthesis" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 71.4;granulocytes: 153.5;monocytes: 71.6" "Cell line enhanced" "Detected in all" "Karpas-707: 133.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045667 Approved Approved Cytosol NA NA 25000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "HPA045667: AB_2679412" "unprognostic (8.66e-2)" "unprognostic (1.07e-3)" "unprognostic (6.03e-2)" "unprognostic (2.57e-2)" "unprognostic (2.95e-2)" "unprognostic (6.53e-2)" "unprognostic (1.76e-2)" "unprognostic (8.40e-2)" "unprognostic (1.72e-1)" "unprognostic (1.53e-1)" "unprognostic (1.48e-1)" "unprognostic (1.48e-1)" "unprognostic (1.60e-2)" "unprognostic (7.67e-2)" "unprognostic (1.73e-1)" "unprognostic (3.43e-1)" "unprognostic (2.13e-3)" 11.1 19.1 7.4 10.8 8.8 19.7 10.9 8.3 8.4 9.7 8.7 11.5 9.7 8.3 9.8 19.0 10.8 8.4 8.5 6.9 8.0 17.2 13.1 10.8 16.4 9.2 8.8 9.0 16.5 21.3 9.3 9.2 8.5 13.0 9.4 7.6 13.9 7.6 11.9 9.0 9.9 5.4 8.0 18.8 11.3 9.7 8.6 12.1 11.2 5.9 12.3 11.2 10.0 10.3 15.6 28.8 11.8 9.2 7.0 6.4 10.1 15.5 7.0 20.3 15.9 16.9 41.2 17.7 26.8 7.8 12.5 15.9 19.2 25.6 10.4 62.6 23.4 31.1 18.8 18.3 19.9 18.3 38.7 8.6 16.7 21.0 32.3 8.2 16.6 25.8 21.3 133.2 14.8 30.0 10.9 28.1 18.9 32.9 13.4 18.2 23.0 38.3 15.3 22.2 28.3 8.3 22.9 31.3 34.6 13.4 38.7 23.4 9.4 20.6 14.4 10.5 27.6 40.5 29.3 30.1 12.7 45.9 23.7 47.2 23.1 153.5 11.6 65.6 19.4 15.7 10.6 13.0 17.6 8.6 11.7 14.5 139.7 18.5 71.6 71.4 12.7 15.8 7.4 8.8 8.3 8.4 6.9 8.0 9.2 8.8 8.5 8.0 8.6 10.3 10.2 16.0 5.2 2.9 10.5 3.8 6.1 8.5 8.6 2.8 9.6 8.8 4.2 4.3 9.7 9.2 0.0 17.5 16.0 19.7 25.4 17.3 1.0 8.2 4.3 10.7 4.2 11.6 1.4 15.3 13.6 7.4 14.8 8.3 12.0 9.9 10.4 5.3 20.0 8.4 1.7 10.9 12.2 15.7 6.7 2.5 4.4 15.5 14.2 2.8 20.0 4.7 8.2 2.5 4.6 18.0 38.1 5.3 33.9 6.5 10.5 19.0 12.2 10.7 6.6 6.3 8.7 6.9 15.7 10.8 4.0 10.9 9.7 11.3 11.7 13.6 PPP1R13L "IASPP, RAI" ENSG00000104881 "Protein phosphatase 1 regulatory subunit 13 like" Q8WUF5 19 45379638-45406349 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 179.4;heart muscle: 139.4;skin 1: 219.8" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 85.6;Granulosa cells: 118.3;Syncytiotrophoblasts: 128.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HBEC3-KT: 130.1;hTCEpi: 189.0;hTERT-HME1: 131.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005016, HPA041231, HPA059883" Approved Enhanced Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" Cytosol "CAB005016: AB_2168576, HPA041231: AB_2677376, HPA059883: AB_2684151" "unprognostic (1.87e-1)" "unprognostic (1.78e-1)" "unprognostic (7.46e-2)" "unprognostic (2.92e-1)" "unprognostic (3.74e-1)" "unprognostic (2.06e-2)" "unprognostic (1.31e-3)" "prognostic unfavorable (3.39e-5)" "unprognostic (1.77e-1)" "prognostic unfavorable (5.40e-4)" "unprognostic (2.52e-3)" "unprognostic (1.92e-2)" "unprognostic (1.55e-3)" "unprognostic (1.34e-1)" "unprognostic (7.69e-2)" "unprognostic (8.87e-2)" "unprognostic (1.02e-1)" 20.4 20.1 11.7 2.9 11.7 0.6 29.6 11.5 14.0 44.9 9.5 11.1 5.0 8.2 15.2 179.4 9.6 6.0 139.4 10.8 14.3 24.8 12.6 20.3 2.6 11.9 11.1 8.8 31.5 12.2 11.8 26.6 11.7 30.8 6.8 13.6 55.6 13.3 5.8 219.8 9.1 5.4 10.0 6.4 12.0 3.1 12.7 4.0 17.7 4.4 18.8 23.6 84.9 12.4 72.3 10.7 4.6 3.8 4.7 2.9 61.5 14.5 2.5 17.5 24.3 23.1 70.6 9.5 5.9 11.9 36.5 97.2 4.0 130.1 16.0 24.0 5.9 1.4 36.3 8.7 10.0 1.0 3.4 4.0 189.0 27.9 131.9 79.2 33.2 7.9 8.1 3.6 1.2 64.7 1.8 1.9 5.3 36.9 18.3 7.4 5.6 1.7 22.9 95.0 2.4 7.6 64.5 68.4 1.6 30.0 58.2 1.9 46.3 23.1 60.9 1.8 76.2 35.1 42.1 6.5 3.3 2.9 5.6 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.2 0.0 11.7 11.7 11.5 14.0 10.8 14.3 11.9 11.1 11.7 10.0 12.7 12.4 14.3 35.3 13.0 9.4 2.0 68.7 85.6 38.4 67.2 1.7 21.9 28.6 38.8 20.0 27.8 20.2 10.4 83.2 2.5 17.8 5.9 34.9 0.7 8.7 3.0 13.4 7.2 10.1 0.8 15.8 37.7 5.6 8.6 17.1 4.5 118.3 11.7 2.5 7.6 0.0 0.9 6.9 14.2 1.6 5.0 0.5 5.9 2.2 12.4 9.4 1.9 2.4 2.1 2.5 1.6 50.4 17.2 12.4 6.1 44.2 22.6 3.9 16.3 26.8 6.6 8.4 14.1 2.7 2.1 81.2 71.0 128.5 2.5 2.8 9.0 63.4 PPP1R37 LRRC68 ENSG00000104866 "Protein phosphatase 1 regulatory subunit 37" O75864 19 45091396-45148077 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 77.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "RT4: 69.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041500 Approved Approved Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 15: RT4 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" Cytosol "HPA041500: AB_10795122" "unprognostic (8.45e-2)" "unprognostic (5.23e-2)" "unprognostic (8.34e-2)" "unprognostic (1.04e-1)" "unprognostic (1.74e-1)" "unprognostic (1.79e-1)" "unprognostic (1.04e-3)" "unprognostic (2.16e-1)" "unprognostic (1.08e-1)" "unprognostic (2.89e-3)" "unprognostic (7.72e-3)" "unprognostic (5.44e-2)" "unprognostic (1.32e-2)" "unprognostic (3.40e-1)" "unprognostic (1.40e-1)" "unprognostic (4.71e-2)" "prognostic favorable (2.04e-4)" 10.4 26.9 11.3 5.8 12.8 4.8 13.0 7.9 16.7 17.9 1.2 14.3 12.1 15.7 3.2 19.8 13.1 5.3 14.8 12.3 4.7 18.2 14.0 11.7 5.2 6.6 4.9 13.5 16.4 7.2 39.3 5.3 6.6 20.0 3.6 8.0 18.4 8.8 20.9 21.3 14.6 4.1 1.8 14.0 28.3 16.5 6.7 5.7 20.4 5.4 3.1 21.7 16.9 10.8 26.2 25.4 9.2 13.4 11.6 7.8 18.4 18.8 10.6 12.8 14.6 11.5 14.2 7.1 13.4 10.0 11.8 20.1 6.3 14.4 3.6 9.3 15.7 6.1 13.6 14.3 14.4 6.4 10.1 10.0 11.1 12.1 7.7 13.7 10.4 9.6 10.8 5.5 7.1 34.2 13.5 8.9 8.7 18.7 15.1 16.3 10.9 5.3 8.4 69.5 28.2 13.0 16.0 33.2 29.3 4.7 21.3 9.4 16.4 15.2 18.2 9.1 17.0 9.3 6.3 5.3 19.7 6.4 14.6 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.3 12.8 7.9 16.7 12.3 4.7 6.6 4.9 6.6 1.8 6.7 10.8 9.4 6.4 3.4 8.5 8.1 7.6 11.1 6.8 13.1 48.6 16.9 11.7 6.2 15.7 5.6 3.7 39.6 21.1 9.7 21.9 7.9 17.9 8.8 9.8 12.1 10.3 30.6 4.8 18.9 9.8 19.0 9.8 30.5 10.9 0.0 12.1 11.0 7.4 17.9 77.4 15.2 27.7 10.2 6.4 6.3 7.0 12.2 6.2 12.4 5.6 4.4 22.7 9.2 11.6 14.3 12.0 23.4 12.4 13.1 10.6 25.6 18.2 5.9 44.1 19.7 10.3 10.1 21.6 23.9 14.3 9.5 18.3 10.4 16.0 22.3 11.4 PPP1R3B "FLJ14005, GL, PPP1R4" ENSG00000173281 "Protein phosphatase 1 regulatory subunit 3B" Q86XI6 8 9136255-9151574 "Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 144.9;skeletal muscle: 95.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 69.9;Hepatocytes: 184.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "basophil: 53.6;eosinophil: 15.8;neutrophil: 50.4" "Lineage enriched" "Detected in all" 19 "granulocytes: 53.6" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 47.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA028731 Enhanced Approved Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 15: Hepatocytes - Hemostasis" Cytosol "HPA028731: AB_10602120" "unprognostic (4.97e-3)" "unprognostic (1.45e-2)" "unprognostic (2.82e-1)" "unprognostic (3.46e-2)" "unprognostic (2.39e-1)" "unprognostic (5.81e-2)" "unprognostic (1.52e-2)" "unprognostic (2.68e-1)" "unprognostic (4.13e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (1.31e-4)" "unprognostic (4.98e-2)" "prognostic unfavorable (4.08e-7)" "prognostic unfavorable (6.03e-5)" "unprognostic (3.33e-1)" "unprognostic (6.86e-2)" "unprognostic (1.21e-1)" 24.1 7.5 1.9 8.2 2.8 12.3 15.9 3.4 3.8 19.6 5.9 16.1 4.6 19.8 4.4 17.2 12.9 9.0 29.9 1.7 3.1 7.6 144.9 9.2 4.3 4.8 3.0 10.4 5.1 50.1 3.3 10.4 4.1 21.7 9.5 7.1 13.9 18.6 95.4 12.3 7.2 12.0 3.1 7.7 12.0 7.1 3.9 4.5 11.7 17.7 3.6 26.4 15.0 4.5 6.7 2.5 7.3 2.5 17.9 15.1 26.3 2.4 7.9 2.9 3.5 10.0 3.1 2.3 3.9 5.0 16.1 1.2 1.3 1.9 3.1 7.2 1.1 4.0 1.0 0.0 8.0 2.0 17.1 12.4 5.9 2.5 14.6 22.0 47.3 11.6 3.1 5.6 1.1 4.1 11.2 3.8 10.6 15.2 2.2 4.5 9.2 4.0 28.6 26.9 0.0 13.6 4.4 0.1 18.6 11.6 3.4 4.1 32.9 8.5 2.9 1.7 3.1 3.1 7.5 0.0 14.8 6.2 2.6 53.6 1.6 15.8 2.2 1.1 1.8 1.6 2.0 1.2 0.9 1.2 2.7 1.5 50.4 2.2 0.7 1.8 1.5 1.6 1.9 2.8 3.4 3.8 1.7 3.1 4.8 3.0 4.1 3.1 3.9 4.5 16.7 12.8 34.5 0.7 5.5 10.7 18.8 7.2 3.4 3.7 19.4 12.7 69.9 24.3 21.8 9.2 6.2 12.9 7.6 26.7 3.9 8.8 20.3 29.5 21.9 21.0 0.0 0.8 0.8 12.7 38.3 12.7 9.7 51.7 33.6 10.4 31.1 184.7 6.9 6.7 0.4 11.5 8.2 9.8 27.9 5.2 9.6 15.6 5.4 3.7 3.1 3.9 4.1 3.5 1.4 18.4 7.5 18.0 4.5 8.0 7.4 6.8 30.8 13.0 13.1 10.9 17.9 1.7 5.7 0.6 12.1 18.3 10.8 9.4 5.5 2.2 PPP2R1A "PP2A-Aalpha, PP2AA, PR65A" ENSG00000105568 "Protein phosphatase 2 scaffold subunit Aalpha" P30153 19 52190048-52229518 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chromosome partition" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018599 Approved Cytosol NA NA 2000000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB018599: AB_628178" "unprognostic (1.78e-1)" "unprognostic (2.31e-2)" "unprognostic (4.52e-2)" "unprognostic (2.87e-1)" "unprognostic (6.67e-2)" "unprognostic (7.82e-2)" "prognostic unfavorable (1.76e-4)" "prognostic unfavorable (2.50e-4)" "unprognostic (4.30e-2)" "unprognostic (3.06e-1)" "unprognostic (6.48e-3)" "unprognostic (8.28e-2)" "prognostic favorable (1.20e-4)" "unprognostic (1.97e-1)" "unprognostic (3.57e-2)" "unprognostic (1.70e-2)" "unprognostic (9.19e-2)" 98.5 300.7 305.0 60.5 311.1 58.1 98.7 292.0 394.2 126.9 261.4 115.7 91.5 126.8 101.0 164.4 126.8 63.2 322.8 342.6 299.4 156.9 106.0 87.5 72.7 308.9 301.1 163.7 100.7 129.9 123.9 69.1 312.8 123.3 82.2 89.8 99.8 92.2 239.7 119.3 98.5 96.0 280.1 87.6 106.0 67.2 331.7 76.9 107.9 170.7 90.0 123.5 121.9 299.2 153.6 248.4 210.9 182.0 166.9 173.4 105.3 130.3 173.2 174.1 151.1 129.3 122.1 132.5 91.0 213.9 95.7 108.8 228.0 197.9 100.6 101.3 562.8 99.6 126.9 148.2 152.6 105.6 93.1 234.3 163.8 163.5 149.2 162.9 167.9 92.1 114.3 96.8 196.3 178.6 159.6 215.4 204.6 162.2 218.4 148.6 118.3 152.5 285.0 251.7 153.3 161.3 149.0 160.1 100.3 136.3 141.9 197.3 153.1 133.2 120.5 65.7 154.2 96.9 151.5 160.0 143.1 109.7 170.5 172.6 172.0 169.4 143.9 212.2 131.0 143.1 126.3 134.3 192.8 157.1 101.6 119.6 103.7 228.6 199.0 119.7 177.5 255.6 305.0 311.1 292.0 394.2 342.6 299.4 308.9 301.1 312.8 280.1 331.7 299.2 55.3 44.8 35.4 21.5 76.0 70.4 99.0 178.0 56.9 114.0 64.5 71.1 100.2 74.4 99.5 119.5 25.0 203.7 47.3 157.0 117.4 213.5 4.4 77.5 79.7 72.4 107.0 39.7 27.4 155.7 259.9 85.7 77.5 100.7 68.5 96.7 65.0 52.8 146.2 144.7 39.5 128.8 144.5 68.1 39.3 10.4 72.4 58.0 53.4 17.8 103.7 118.0 62.8 25.6 29.9 168.2 189.0 85.4 60.3 88.3 147.5 135.3 80.6 61.5 78.9 49.2 90.3 16.5 68.8 74.4 63.2 182.0 64.2 99.7 185.2 104.2 PPP2R2A "B55A, B55alpha, PR52A, PR55A, PR55alpha" ENSG00000221914 "Protein phosphatase 2 regulatory subunit Balpha" P63151 8 26291508-26372680 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042122, HPA042770, CAB079289" Approved Approved Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 59: Non-specific - Translation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB079289: AB_659890, HPA042122: AB_2677859, HPA042770: AB_2678155" "unprognostic (1.17e-1)" "unprognostic (2.68e-2)" "unprognostic (4.29e-3)" "unprognostic (5.34e-2)" "unprognostic (3.44e-2)" "unprognostic (2.11e-2)" "unprognostic (4.64e-3)" "unprognostic (3.65e-1)" "unprognostic (2.48e-1)" "unprognostic (3.87e-2)" "unprognostic (2.71e-2)" "unprognostic (8.60e-2)" "unprognostic (1.60e-1)" "unprognostic (1.31e-1)" "unprognostic (2.90e-1)" "unprognostic (3.44e-2)" "unprognostic (1.16e-1)" 32.1 16.1 8.9 12.7 13.1 4.7 30.4 9.1 14.3 33.1 6.4 19.1 21.7 22.3 8.5 59.6 24.6 14.1 26.7 9.5 10.2 18.0 28.3 25.8 16.0 9.4 9.7 24.7 14.7 14.0 13.5 38.2 9.2 19.5 15.2 10.5 27.0 15.9 53.4 38.9 19.4 18.3 10.2 17.9 17.7 18.1 8.8 16.0 19.4 23.6 25.7 24.2 37.0 13.6 42.1 33.5 52.5 32.2 28.3 43.6 54.2 74.5 49.4 63.1 65.2 48.9 24.2 54.5 19.1 28.9 31.5 51.2 56.9 50.1 78.0 23.8 24.4 43.8 36.6 23.0 42.0 25.2 19.1 29.3 62.4 39.4 52.0 31.7 96.1 27.5 64.1 37.1 51.7 26.0 54.4 17.6 62.5 73.6 20.5 36.1 35.1 41.8 31.0 74.8 21.0 27.7 30.3 27.9 41.0 37.2 26.9 13.7 45.8 28.5 46.0 31.4 47.0 18.6 32.4 80.9 35.1 39.7 52.2 0.6 0.4 1.6 0.4 0.9 0.7 1.3 1.1 1.0 1.1 1.1 0.6 0.9 1.0 0.9 0.9 0.7 1.8 0.7 8.9 13.1 9.1 14.3 9.5 10.2 9.4 9.7 9.2 10.2 8.8 13.6 63.4 73.7 67.8 42.1 59.2 136.6 215.9 81.6 72.8 53.0 65.6 52.5 36.9 27.1 98.8 14.7 47.9 76.6 70.2 57.5 49.0 45.5 47.9 100.5 51.6 82.3 76.9 53.5 95.1 32.2 65.3 65.5 57.6 98.4 55.2 61.0 55.3 34.6 36.6 37.0 49.9 51.2 61.1 32.0 66.1 128.8 46.9 47.6 60.5 72.1 48.1 51.6 35.0 122.6 250.6 61.0 50.1 73.4 53.5 140.0 44.4 43.9 111.2 40.8 52.6 56.1 76.7 44.6 57.2 102.3 142.9 66.9 66.5 59.9 50.6 232.8 PPP2R2B "B55beta, PR52B, PR55-BETA, SCA12" ENSG00000156475 "Protein phosphatase 2 regulatory subunit Bbeta" Q00005 5 146580742-147084784 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Apoptosis "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 77.1;retina: 43.0" "Cell type enhanced" "Detected in many" "Astrocytes: 1539.0;Excitatory neurons: 846.0;Inhibitory neurons: 788.8;Late spermatids: 876.4;Oligodendrocyte precursor cells: 1035.4;Oligodendrocytes: 4480.1" "Cancer enriched" "Detected in some" 8 "glioma: 7.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 5.2;MAIT T-cell: 4.1;memory CD4 T-cell: 2.4;memory CD8 T-cell: 6.2;naive CD8 T-cell: 3.8;NK-cell: 2.9;T-reg: 3.4" "Group enriched" "Detected in many" 9 "NK-cells: 2.9;T-cells: 6.2" "Cell line enhanced" "Detected in some" "HaCaT: 7.2;HDLM-2: 24.2;RT4: 12.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038118, HPA042122, HPA042770" Approved Uncertain Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 44: HDLM-2 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA038118: AB_10697238, HPA042122: AB_2677859, HPA042770: AB_2678155" "unprognostic (4.54e-5)" "unprognostic (1.74e-1)" "unprognostic (1.21e-1)" "unprognostic (2.80e-4)" "unprognostic (2.48e-1)" "unprognostic (1.44e-1)" "unprognostic (2.76e-1)" "unprognostic (1.84e-2)" "unprognostic (2.68e-1)" "unprognostic (3.20e-2)" "unprognostic (9.73e-4)" "unprognostic (4.51e-2)" "unprognostic (1.49e-8)" "unprognostic (2.02e-1)" "unprognostic (3.67e-1)" "unprognostic (5.48e-5)" "unprognostic (1.14e-4)" 1.3 7.8 53.9 0.9 71.4 1.9 0.8 44.7 77.1 1.2 6.0 6.5 1.0 0.4 0.5 1.3 3.6 1.8 2.5 57.8 53.9 3.7 0.7 0.8 1.7 50.7 56.3 0.4 1.9 2.8 14.8 0.7 50.4 1.9 1.9 43.0 1.0 1.0 0.3 3.4 2.2 1.3 50.7 1.8 1.1 18.9 71.6 0.8 3.1 0.3 0.8 7.5 2.0 73.9 0.2 0.0 1.3 2.0 0.2 0.0 0.4 0.7 0.3 0.7 0.2 2.3 1.9 0.2 0.2 0.1 0.0 7.2 0.5 0.4 1.8 24.2 0.4 0.4 4.8 0.6 0.4 0.1 0.4 0.2 1.2 0.0 0.4 0.8 0.3 0.7 0.7 0.5 0.9 0.3 0.2 0.1 2.3 0.0 0.9 1.6 0.2 0.0 1.9 12.5 1.3 0.2 0.3 0.0 0.3 1.4 0.7 0.0 0.4 0.1 0.3 1.7 0.6 0.1 0.4 0.2 0.9 1.9 2.0 0.5 0.0 0.0 5.2 0.0 4.1 0.1 2.4 6.2 0.0 0.0 0.6 3.8 0.1 2.9 0.1 0.0 3.4 1.4 53.9 71.4 44.7 77.1 57.8 53.9 50.7 56.3 50.4 50.7 71.6 73.9 0.5 3.2 1.8 1539.0 0.3 2.0 1.1 2.3 4.6 90.5 0.5 3.6 1.6 10.0 0.9 9.2 150.1 18.9 30.2 0.0 21.5 1.7 295.3 1.0 0.1 2.0 13.1 1.3 846.0 0.0 0.3 1.1 1.1 0.4 0.0 0.0 0.0 0.0 0.9 47.1 788.8 0.0 0.0 1.2 4.7 876.4 3.4 1.4 5.4 58.1 0.3 45.0 57.7 1035.4 4480.1 0.6 0.0 2.2 3.3 1.0 0.0 5.5 0.1 275.4 0.0 0.7 11.0 4.8 2.2 1.6 1.4 5.3 31.0 0.1 0.0 0.9 PPP2R2C "B55gamma, IMYPNO, MGC33570, PR52, PR55G" ENSG00000074211 "Protein phosphatase 2 regulatory subunit Bgamma" Q9Y2T4 4 6320578-6563600 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 106.2" "Group enriched" "Detected in many" 5 "Astrocytes: 61.0;Early spermatids: 67.4;Excitatory neurons: 203.3;Inhibitory neurons: 82.8;Late spermatids: 182.5;Oligodendrocytes: 94.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 10.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 31.4;A549: 46.1;CAPAN-2: 28.2;GAMG: 68.4;MCF7: 36.2;PC-3: 38.9;SCLC-21H: 39.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042122, HPA042770, HPA060473" Approved Approved Cytosol NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA042122: AB_2677859, HPA042770: AB_2678155, HPA060473: AB_2684291" "unprognostic (9.39e-2)" "unprognostic (7.10e-2)" "unprognostic (9.12e-2)" "unprognostic (1.14e-3)" "unprognostic (1.48e-1)" "unprognostic (5.91e-2)" "unprognostic (2.70e-4)" "prognostic unfavorable (4.94e-4)" "unprognostic (1.77e-1)" "unprognostic (3.90e-1)" "unprognostic (4.67e-2)" "unprognostic (2.77e-1)" "unprognostic (1.36e-13)" "unprognostic (2.52e-1)" "unprognostic (3.92e-2)" "unprognostic (2.66e-3)" "unprognostic (9.90e-3)" 0.8 6.2 72.9 0.6 86.7 0.0 1.4 42.1 106.2 18.0 0.0 1.1 0.8 27.0 7.4 35.9 9.9 0.4 2.5 85.7 44.5 0.3 0.1 0.1 0.3 52.5 52.7 0.6 0.7 1.5 22.6 0.1 55.1 5.0 0.3 10.9 5.3 14.5 0.8 34.0 1.2 11.9 62.3 0.3 0.8 7.3 66.9 2.7 0.1 0.9 3.1 0.9 11.5 91.2 31.4 46.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 28.2 0.0 19.0 0.0 68.4 13.7 20.0 0.7 0.0 0.0 2.4 0.0 3.2 3.7 0.7 0.0 0.1 6.6 11.4 0.0 0.0 0.0 0.1 4.2 0.0 0.1 6.6 36.2 0.0 0.1 2.2 0.6 38.9 0.0 0.0 1.2 0.0 0.1 39.1 7.5 1.5 0.1 0.0 1.1 18.9 0.1 0.0 0.2 22.7 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 72.9 86.7 42.1 106.2 85.7 44.5 52.5 52.7 55.1 62.3 66.9 91.2 0.2 0.0 0.0 61.0 0.0 14.7 0.4 0.8 4.6 11.0 1.9 0.4 4.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 67.4 0.8 5.7 0.6 0.0 0.0 203.3 0.2 0.0 0.2 0.0 2.4 0.0 0.0 0.0 0.0 0.1 3.3 82.8 0.0 0.0 0.0 1.1 182.5 6.8 0.0 0.0 4.7 0.0 6.5 0.0 14.1 94.6 2.4 0.0 4.5 0.0 1.3 0.0 0.2 0.0 3.1 0.0 0.0 2.5 2.3 1.6 6.5 22.0 0.0 0.2 0.1 0.0 0.2 PPP2R2D "B55D, B55delta, MDS026" ENSG00000175470 "Protein phosphatase 2 regulatory subunit Bdelta" Q66LE6 10 131901008-131959834 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 15.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042122, HPA042770" Approved Approved Cytosol NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 52: Non-specific - Transcription" Cytosol "HPA042122: AB_2677859, HPA042770: AB_2678155" "unprognostic (7.75e-3)" "unprognostic (7.11e-2)" "prognostic unfavorable (3.14e-4)" "unprognostic (1.40e-1)" "unprognostic (3.57e-1)" "unprognostic (9.64e-3)" "unprognostic (1.83e-1)" "unprognostic (3.13e-2)" "unprognostic (1.76e-2)" "unprognostic (8.74e-2)" "unprognostic (8.46e-2)" "unprognostic (8.04e-2)" "unprognostic (4.41e-3)" "unprognostic (1.10e-1)" "unprognostic (6.57e-2)" "unprognostic (6.66e-2)" "unprognostic (1.90e-2)" 1.5 3.0 4.5 1.2 5.4 0.0 1.4 7.0 5.8 2.1 3.8 2.8 2.1 1.6 2.0 1.6 1.6 1.6 3.3 4.9 4.1 1.8 1.6 2.3 2.4 4.1 4.1 3.6 15.9 3.2 2.3 1.9 4.1 1.8 1.9 2.8 3.3 1.9 2.8 2.7 2.4 1.3 3.6 1.8 2.1 1.3 4.6 1.7 2.2 2.9 1.5 2.3 1.9 4.9 4.4 3.8 2.4 1.8 3.3 2.6 3.4 1.5 3.1 2.9 3.1 3.1 3.6 1.8 1.0 1.8 1.8 7.9 3.2 0.7 3.1 4.5 4.2 3.0 3.7 1.8 1.1 3.2 3.4 0.9 6.7 3.2 4.5 4.6 2.0 2.6 3.9 0.8 3.2 2.1 1.5 7.3 1.5 1.5 3.4 2.0 1.6 0.5 2.3 0.6 1.9 2.6 1.9 1.6 1.8 2.5 1.4 2.4 2.8 1.6 0.7 2.3 8.1 2.8 1.6 2.3 1.4 1.8 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 5.4 7.0 5.8 4.9 4.1 4.1 4.1 4.1 3.6 4.6 4.9 26.8 19.2 14.3 22.2 20.0 37.3 37.4 6.4 20.5 55.0 25.8 23.6 36.3 14.3 10.2 9.2 10.4 10.6 36.1 27.6 19.6 9.8 12.7 21.5 24.8 19.0 10.7 18.7 43.0 17.7 13.6 21.8 19.9 32.3 6.3 33.1 13.2 23.2 14.1 52.2 37.5 18.2 8.2 12.0 17.6 6.4 17.4 23.3 12.4 26.2 10.5 28.3 18.6 29.7 38.1 16.8 18.0 20.7 20.3 39.1 20.0 29.6 5.7 32.6 26.3 29.2 23.2 14.3 20.1 18.8 34.0 11.8 24.4 39.5 19.1 39.6 PPP2R5A "B56A, B56alpha, PR61A" ENSG00000066027 "Protein phosphatase 2 regulatory subunit B'alpha" Q15172 1 212285410-212361853 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 252.7;Late spermatids: 547.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059288, HPA078841" Approved Supported Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA059288: AB_2683966, HPA078841: " "unprognostic (3.56e-1)" "unprognostic (2.71e-1)" "unprognostic (8.48e-2)" "unprognostic (2.54e-1)" "unprognostic (9.21e-2)" "unprognostic (1.01e-1)" "unprognostic (5.01e-2)" "unprognostic (1.12e-2)" "unprognostic (8.07e-2)" "unprognostic (1.84e-2)" "unprognostic (3.04e-1)" "unprognostic (5.63e-2)" "unprognostic (1.40e-3)" "unprognostic (8.33e-2)" "unprognostic (1.42e-1)" "unprognostic (2.17e-1)" "unprognostic (1.39e-1)" 60.2 12.0 35.5 20.0 40.6 86.5 38.3 34.4 34.9 24.7 27.4 34.2 25.7 20.1 18.4 51.3 19.2 27.7 50.4 31.0 35.6 35.6 51.6 57.7 31.0 36.3 40.8 15.3 36.9 23.5 13.2 35.9 36.1 22.6 37.0 23.9 36.3 22.2 36.7 30.8 33.4 22.2 35.0 49.5 44.5 17.4 42.6 36.3 41.8 56.6 31.3 34.7 30.2 39.6 45.4 19.1 9.5 19.1 102.5 62.2 76.1 19.6 38.3 21.9 20.6 57.1 45.7 31.9 14.5 31.5 22.9 32.0 18.3 27.9 22.8 27.5 23.1 20.7 19.9 20.8 33.1 43.3 30.7 25.7 36.4 20.1 29.0 27.7 53.3 28.0 29.6 33.4 12.1 19.7 17.1 28.5 16.0 40.6 39.5 22.0 15.2 40.6 38.5 20.9 13.6 9.1 27.3 84.7 65.0 40.0 52.7 38.0 11.4 15.3 15.6 24.2 21.2 50.9 42.7 42.1 18.4 32.6 11.5 18.0 2.0 10.1 4.4 2.3 3.0 1.4 3.4 4.0 1.4 2.2 2.0 4.0 9.8 3.3 3.3 1.5 5.2 1.4 35.5 40.6 34.4 34.9 31.0 35.6 36.3 40.8 36.1 35.0 42.6 39.6 66.7 99.3 104.4 71.5 34.2 68.6 22.1 9.0 40.9 24.6 30.1 18.5 65.8 47.1 17.4 14.7 2.1 10.9 56.2 51.2 97.8 25.9 252.7 25.5 17.7 53.3 16.2 22.9 21.3 34.8 26.9 18.7 43.8 53.5 40.0 6.6 38.6 52.2 22.1 52.2 13.8 33.9 8.2 34.8 20.6 547.2 19.3 34.1 17.8 45.0 35.1 37.4 53.5 32.6 115.2 27.8 32.5 14.3 29.6 31.0 30.8 20.9 21.3 11.1 32.9 14.8 36.5 18.4 10.9 66.2 81.3 8.2 54.1 58.3 30.8 45.7 PPP2R5E "B56E, B56epsilon" ENSG00000154001 "Protein phosphatase 2 regulatory subunit B'epsilon" Q16537 14 63371364-63543377 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 283.4;Horizontal cells: 262.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006034, CAB072342" Approved Supported Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "CAB072342: , HPA006034: AB_1079670" "unprognostic (1.58e-1)" "unprognostic (1.65e-1)" "unprognostic (3.11e-2)" "unprognostic (1.45e-1)" "unprognostic (2.06e-1)" "unprognostic (2.17e-1)" "prognostic unfavorable (1.95e-4)" "unprognostic (2.26e-1)" "unprognostic (2.91e-1)" "unprognostic (1.57e-2)" "unprognostic (1.70e-2)" "unprognostic (4.62e-2)" "prognostic favorable (4.16e-4)" "unprognostic (1.23e-1)" "unprognostic (9.51e-2)" "unprognostic (1.92e-1)" "unprognostic (8.22e-2)" 12.7 12.5 9.5 13.5 11.0 14.5 12.5 10.3 11.1 14.6 7.2 17.0 10.7 14.9 10.2 19.8 11.7 12.0 15.7 11.4 11.1 14.7 15.8 12.7 15.4 7.4 7.6 12.6 10.9 17.5 6.6 16.0 7.9 12.7 20.0 26.7 9.2 12.6 17.8 11.8 12.3 15.0 7.6 14.3 12.0 14.3 10.4 19.2 20.2 16.5 17.0 17.1 9.8 7.8 90.5 26.0 46.7 22.1 31.6 37.0 44.5 37.1 30.4 39.5 39.1 33.1 35.4 39.6 22.1 38.1 29.3 36.2 48.1 34.4 67.8 36.2 11.8 25.7 18.1 27.7 33.7 41.7 30.4 27.1 37.7 38.8 42.7 28.8 40.2 39.8 33.3 41.9 43.8 60.2 41.8 18.7 35.3 37.7 46.8 41.9 47.8 30.1 38.2 68.1 26.5 51.6 47.7 39.1 25.0 40.1 57.4 20.8 37.8 61.7 68.6 31.7 33.0 15.2 24.4 50.9 28.4 26.3 42.7 1.4 1.3 1.3 2.0 1.4 1.9 1.1 2.2 2.5 1.2 1.7 1.7 1.9 1.0 4.5 1.9 1.9 1.4 0.6 9.5 11.0 10.3 11.1 11.4 11.1 7.4 7.6 7.9 7.6 10.4 7.8 52.1 89.8 55.5 54.2 52.8 80.4 56.9 34.0 60.3 65.0 49.3 27.8 61.7 44.3 35.3 22.0 64.6 27.2 54.8 55.0 29.4 46.4 283.4 65.1 57.2 52.5 27.1 41.2 110.4 47.7 41.5 44.8 33.1 74.6 24.1 48.6 41.0 45.1 29.8 262.5 131.6 51.6 28.5 38.7 49.0 46.6 43.8 42.3 37.4 59.0 49.7 38.4 61.8 93.5 91.8 41.4 48.1 43.2 55.9 58.5 24.9 41.2 41.6 81.2 26.3 51.5 71.1 74.9 22.5 63.1 91.6 30.6 57.0 47.8 70.2 46.9 PPP4R4 "CFAP14, KIAA1622, PP4R4" ENSG00000119698 "Protein phosphatase 4 regulatory subunit 4" Q6NUP7 14 94146128-94279734 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 7.9" "Cell type enhanced" "Detected in many" "Astrocytes: 44.4;Cone photoreceptor cells: 75.0;Excitatory neurons: 63.1;Inhibitory neurons: 63.0;Spermatocytes: 33.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-HME1: 6.7;RH-30: 19.4;T-47d: 23.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041866, HPA050321" Approved Supported Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA041866: AB_10804120, HPA050321: AB_2681086" "unprognostic (2.65e-3)" "unprognostic (3.06e-1)" "unprognostic (9.07e-2)" "unprognostic (9.49e-3)" "unprognostic (2.48e-2)" "unprognostic (1.59e-1)" "unprognostic (3.88e-2)" "unprognostic (2.45e-1)" "unprognostic (1.25e-1)" "unprognostic (8.85e-2)" "unprognostic (6.91e-3)" "unprognostic (1.72e-2)" "unprognostic (8.95e-2)" "unprognostic (7.53e-2)" "unprognostic (3.35e-2)" "unprognostic (1.77e-1)" "unprognostic (6.24e-2)" 0.2 0.4 2.7 0.3 3.0 0.1 0.5 2.2 4.0 4.3 1.0 0.1 0.0 0.8 0.0 0.3 1.6 0.3 0.2 3.3 3.6 0.3 3.0 1.5 0.2 2.8 2.7 5.1 0.4 0.9 2.6 0.5 2.4 0.4 0.1 5.4 0.3 0.6 0.1 0.6 0.1 0.3 1.8 0.0 0.7 7.9 3.4 0.1 0.2 0.0 0.6 0.2 1.2 4.2 0.8 0.1 3.5 0.9 0.8 0.0 0.9 0.4 3.1 1.0 0.9 0.2 0.9 0.0 0.0 0.0 2.5 0.1 4.5 4.7 0.6 0.3 0.7 0.0 0.0 1.9 0.3 0.0 0.6 0.0 0.9 0.1 6.7 0.0 0.0 2.1 0.0 0.3 0.6 1.0 0.0 0.1 1.8 0.0 0.1 0.2 19.4 0.1 0.2 0.9 0.4 0.1 0.1 0.1 0.1 1.3 23.6 0.0 0.0 3.0 2.9 0.2 0.3 0.9 0.1 0.6 1.8 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 3.0 2.2 4.0 3.3 3.6 2.8 2.7 2.4 1.8 3.4 4.2 0.1 3.2 9.5 44.4 0.1 4.8 4.9 4.9 5.7 1.4 3.6 0.8 0.4 0.0 2.9 0.0 75.0 0.0 0.0 0.0 0.0 2.4 17.9 3.5 0.2 0.6 0.0 0.0 63.1 0.4 0.2 0.5 2.0 3.1 0.0 19.5 6.4 1.0 0.1 1.7 63.0 0.0 2.0 1.3 0.7 18.0 5.9 0.2 0.0 1.9 0.0 6.0 0.0 17.6 3.7 0.2 0.0 5.7 0.1 17.8 0.0 0.2 14.5 0.8 0.0 0.6 1.6 33.7 9.2 1.6 2.6 0.0 0.4 1.2 0.0 7.2 PPP6R1 "KIAA1115, SAP190, SAPS1" ENSG00000105063 "Protein phosphatase 6 regulatory subunit 1" Q9UPN7 19 55229779-55259017 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 237.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 28.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043989, HPA063681" Approved Enhanced Cytosol No No 19000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "HPA043989: AB_10987309, HPA063681: AB_2685087" "unprognostic (1.15e-1)" "unprognostic (2.34e-1)" "unprognostic (1.20e-2)" "unprognostic (1.11e-1)" "unprognostic (1.65e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (3.82e-6)" "unprognostic (2.22e-2)" "unprognostic (5.44e-2)" "unprognostic (5.41e-2)" "unprognostic (3.35e-3)" "unprognostic (1.63e-3)" "unprognostic (2.04e-1)" "unprognostic (1.23e-1)" "unprognostic (3.65e-2)" "unprognostic (3.30e-2)" "unprognostic (2.20e-1)" 21.8 36.8 31.6 52.7 35.4 96.4 20.3 8.0 35.7 22.0 19.4 28.3 38.1 25.7 5.1 35.2 26.6 23.8 28.3 41.7 12.8 23.8 25.5 28.3 82.4 15.0 13.2 21.1 20.3 22.6 29.7 21.2 15.6 23.5 12.2 8.8 24.1 21.4 38.7 28.5 42.4 18.4 8.3 61.5 42.6 89.7 20.6 62.2 27.3 20.2 49.3 33.4 23.4 18.1 101.2 143.4 28.7 46.1 33.5 30.8 73.1 63.1 54.7 64.8 55.2 95.4 67.9 261.0 33.7 56.6 48.2 48.2 10.3 65.9 25.1 98.2 241.8 198.5 71.8 71.0 57.5 295.9 187.6 45.4 37.4 64.5 43.4 34.7 42.2 178.7 105.5 112.1 42.5 64.5 218.1 105.5 39.3 82.2 116.5 131.8 56.4 216.0 45.9 126.6 81.8 45.5 58.7 69.7 62.2 24.6 38.3 219.7 55.3 101.3 49.7 39.4 96.4 55.4 108.7 184.1 92.4 240.5 79.1 0.0 2.8 6.5 11.7 3.9 6.6 3.3 4.8 9.3 4.0 2.7 4.9 7.5 3.1 7.8 3.4 28.6 3.6 6.8 31.6 35.4 8.0 35.7 41.7 12.8 15.0 13.2 15.6 8.3 20.6 18.1 14.7 12.8 19.8 11.1 27.2 2.8 8.9 1.0 11.4 16.3 14.2 10.4 2.6 18.6 6.2 18.4 10.4 11.1 66.2 21.7 0.0 21.2 237.3 36.3 13.6 15.8 15.1 41.4 14.4 28.7 9.3 9.7 50.4 19.7 7.6 19.7 16.1 22.3 32.4 30.3 10.6 15.7 2.0 31.2 4.8 55.3 18.6 34.0 0.0 9.4 21.9 14.7 51.5 6.0 11.3 47.3 18.8 19.5 27.0 22.1 34.2 12.3 12.6 15.3 19.7 12.5 10.7 38.5 41.0 13.9 3.4 11.4 39.6 31.3 14.2 50.7 PREP ENSG00000085377 "Prolyl endopeptidase" P48147 6 105273218-105454062 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 84.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 79.7;Syncytiotrophoblasts: 67.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025414, HPA031388, HPA031389, HPA031390" Supported Supported Cytosol NA NA 1700000 "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "CAB025414: , HPA031388: AB_2673855, HPA031389: AB_2673856, HPA031390: AB_2673857" "unprognostic (3.05e-2)" "unprognostic (9.09e-3)" "unprognostic (2.85e-2)" "unprognostic (5.46e-2)" "unprognostic (3.36e-1)" "prognostic unfavorable (3.33e-4)" "unprognostic (2.63e-3)" "unprognostic (2.39e-1)" "unprognostic (6.78e-2)" "unprognostic (5.81e-2)" "unprognostic (2.66e-2)" "unprognostic (1.15e-1)" "unprognostic (4.47e-3)" "unprognostic (2.74e-2)" "unprognostic (8.98e-2)" "unprognostic (6.59e-2)" "unprognostic (2.33e-1)" 17.3 17.4 7.2 14.6 8.1 14.3 17.7 7.4 12.0 15.2 7.8 32.1 23.6 15.8 12.1 21.1 13.0 8.7 22.5 8.8 7.3 11.3 19.0 16.2 13.6 6.7 7.7 16.0 19.2 20.5 13.0 17.8 6.8 11.6 37.5 15.4 18.6 9.0 84.8 33.4 25.6 15.3 6.6 14.3 18.7 21.4 8.8 16.4 12.3 46.9 16.2 21.4 17.5 8.5 22.3 26.9 27.9 32.1 63.1 37.1 27.7 28.6 27.0 37.2 39.0 35.9 14.2 28.5 26.8 33.9 35.0 33.3 41.8 86.5 42.7 41.8 37.4 38.1 21.7 40.0 25.3 40.5 26.2 35.8 53.4 27.6 71.7 28.0 35.4 50.1 67.4 49.8 45.5 38.8 25.8 41.4 27.9 44.2 25.0 41.1 48.4 18.3 28.2 53.8 36.0 51.8 25.3 42.0 21.7 35.3 17.9 61.9 36.1 17.3 23.9 21.6 36.2 14.2 9.7 38.5 30.4 42.6 56.6 5.5 15.2 8.4 16.3 16.8 16.8 9.3 14.2 17.1 16.5 6.9 12.9 15.5 0.8 19.9 22.7 7.0 13.6 13.5 7.2 8.1 7.4 12.0 8.8 7.3 6.7 7.7 6.8 6.6 8.8 8.5 6.3 3.2 6.7 22.9 10.1 10.8 6.8 12.0 5.7 5.1 6.0 5.5 14.8 7.2 13.6 7.3 14.6 28.2 14.5 19.3 5.9 10.4 1.4 6.6 15.1 10.1 19.3 11.2 79.7 11.7 35.9 10.6 24.5 11.6 13.4 11.2 7.5 15.1 15.0 13.5 48.3 29.4 10.2 14.2 10.8 3.2 10.8 13.3 5.4 27.2 19.1 3.3 5.2 28.6 18.7 18.0 29.1 9.1 11.0 5.3 18.5 8.8 4.8 10.4 0.0 8.3 10.3 3.9 18.8 12.9 8.5 67.9 16.1 14.4 38.2 8.5 PRF1 "HPLH2, P1, PFP" ENSG00000180644 "Perforin 1" P14222 10 70597348-70602759 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Cytolysis "Cancer-related genes, Disease variant, Familial hemophagocytic lymphohistiocytosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 28.6;lung: 16.5;lymphoid tissue: 49.4" "Cell type enhanced" "Detected in some" "dendritic cells: 542.1;NK-cells: 1231.7;T-cells: 265.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "gdT-cell: 900.4;MAIT T-cell: 628.8;memory CD8 T-cell: 499.1;naive CD8 T-cell: 313.0;NK-cell: 656.8" "Group enriched" "Detected in all" 50 "NK-cells: 656.8;T-cells: 900.4" "Cell line enriched" "Detected in some" 11 "HDLM-2: 240.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002436, HPA037940" Approved Approved Cytosol "Intracellular and membrane" NA NA 2100000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "CAB002436: AB_563955, HPA037940: AB_2675747" "unprognostic (6.11e-3)" "unprognostic (1.26e-2)" "unprognostic (1.71e-1)" "prognostic favorable (2.09e-4)" "unprognostic (1.87e-2)" "prognostic favorable (3.54e-4)" "unprognostic (6.98e-3)" "unprognostic (2.62e-1)" "unprognostic (1.44e-3)" "unprognostic (1.69e-2)" "unprognostic (5.22e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.08e-5)" "unprognostic (7.38e-2)" "unprognostic (2.70e-1)" "unprognostic (7.97e-3)" "unprognostic (5.22e-3)" 5.0 2.0 0.7 7.6 0.7 28.6 2.7 0.7 1.3 1.3 1.3 2.2 2.3 3.5 1.1 1.9 1.9 4.2 2.2 0.6 0.6 1.7 6.3 16.5 20.3 1.4 0.7 1.0 1.0 0.5 0.9 2.7 1.0 1.5 1.4 0.0 2.3 1.2 2.6 0.9 5.2 2.0 1.3 49.4 4.7 0.6 1.0 5.8 2.6 1.5 4.9 3.8 1.9 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 240.1 0.0 1.4 0.0 7.4 0.0 0.3 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.1 22.2 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.1 0.0 5.2 1.9 0.9 900.4 1.7 628.8 4.0 125.8 499.1 2.0 3.5 52.1 313.0 15.4 656.8 2.6 2.9 108.8 587.5 0.7 0.7 0.7 1.3 0.6 0.6 1.4 0.7 1.0 1.3 1.0 1.0 3.1 3.2 13.6 0.0 4.4 0.4 0.1 0.0 0.6 0.0 0.5 0.5 0.8 1.5 2.5 0.0 0.0 0.2 542.1 0.1 0.0 0.3 0.0 0.2 0.3 1.9 0.0 19.0 0.0 0.0 0.1 2.1 7.7 0.4 8.8 0.0 10.8 2.7 0.1 0.0 0.0 0.0 0.0 7.8 2.3 0.0 0.0 5.7 0.0 1.9 7.4 0.0 1231.7 0.0 0.1 0.0 0.0 0.0 88.5 0.1 0.1 1.6 1.5 0.0 0.0 1.1 0.8 0.0 0.0 0.5 0.9 0.7 265.4 0.0 0.1 0.0 PRKAR1A "CNC1, PRKAR1, TSE1" ENSG00000108946 "Protein kinase cAMP-dependent type I regulatory subunit alpha" P10644 17 68511780-68551319 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 606.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019378, HPA049979" Approved Approved Cytosol NA NA 1800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "CAB019378: , HPA049979: AB_2680980" "unprognostic (8.69e-2)" "unprognostic (6.97e-2)" "unprognostic (5.34e-2)" "unprognostic (2.04e-1)" "unprognostic (1.68e-1)" "unprognostic (4.39e-2)" "unprognostic (2.61e-1)" "unprognostic (6.42e-2)" "unprognostic (2.27e-1)" "unprognostic (2.30e-1)" "unprognostic (1.19e-2)" "unprognostic (5.55e-2)" "unprognostic (8.56e-3)" "unprognostic (6.26e-2)" "unprognostic (6.92e-2)" "unprognostic (3.29e-2)" "unprognostic (1.11e-1)" 125.9 158.2 72.0 124.1 83.2 57.1 118.4 76.7 119.1 151.2 97.3 70.0 51.7 145.5 122.3 98.5 141.3 125.2 430.0 89.0 102.1 164.3 150.8 163.7 111.4 85.6 91.8 202.8 63.1 300.2 88.0 164.3 105.0 114.5 79.1 132.2 169.7 137.6 250.6 63.8 58.7 132.1 71.7 121.7 86.9 130.8 91.8 109.4 173.6 147.4 103.6 136.4 67.6 93.5 95.5 180.0 225.9 136.1 294.6 331.7 33.9 125.7 257.9 192.2 168.6 70.5 125.5 96.3 84.3 276.7 196.8 77.2 168.8 204.2 273.8 65.8 60.4 149.1 154.0 233.0 213.0 115.8 160.2 239.1 207.4 222.3 185.9 215.0 324.6 80.8 68.5 147.2 236.4 181.0 128.2 60.9 83.9 97.7 121.4 88.1 373.6 106.7 292.4 204.3 81.8 110.3 115.4 207.6 496.8 208.5 162.8 161.1 232.2 269.4 127.6 123.3 119.0 121.6 93.5 142.4 163.0 107.8 171.8 149.6 108.3 189.4 48.6 101.0 48.8 42.8 35.9 43.6 105.9 32.3 32.1 35.9 208.2 76.1 120.9 34.7 50.9 113.5 72.0 83.2 76.7 119.1 89.0 102.1 85.6 91.8 105.0 71.7 91.8 93.5 134.1 147.4 263.4 38.5 126.0 142.8 100.1 136.8 116.7 99.6 106.8 65.4 606.2 81.5 156.4 252.0 66.7 77.4 127.4 58.1 178.1 80.7 407.9 142.9 116.4 131.8 136.9 52.5 76.1 52.0 86.8 163.2 78.5 110.3 185.0 78.2 158.1 120.7 146.1 139.7 78.4 53.3 136.3 176.2 171.1 93.7 133.6 151.1 192.1 46.9 142.3 125.1 78.2 57.3 76.3 74.6 51.5 190.7 95.6 85.3 27.1 210.1 307.7 59.9 85.5 123.2 210.9 219.8 54.2 122.4 131.7 82.5 117.3 184.0 43.9 112.8 PRPSAP1 PAP39 ENSG00000161542 "Phosphoribosyl pyrophosphate synthetase associated protein 1" Q14558 17 76309478-76384521 "Predicted intracellular proteins" "Nucleotide biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062396 Approved Cytosol NA NA 24000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 5: Muller glia cells - Visual perception" Cytosol "HPA062396: AB_2684750" "unprognostic (1.12e-1)" "unprognostic (3.37e-2)" "prognostic favorable (1.39e-5)" "unprognostic (3.31e-2)" "unprognostic (3.11e-2)" "unprognostic (8.45e-3)" "unprognostic (1.09e-1)" "unprognostic (7.19e-2)" "unprognostic (2.66e-2)" "unprognostic (2.37e-2)" "unprognostic (6.51e-2)" "unprognostic (4.10e-3)" "unprognostic (1.29e-1)" "unprognostic (1.22e-1)" "unprognostic (5.72e-2)" "unprognostic (8.20e-2)" "unprognostic (5.37e-2)" 26.4 26.2 24.2 13.7 24.3 22.2 27.6 25.1 29.3 29.1 24.0 22.7 16.6 22.6 28.0 34.9 21.8 18.9 21.5 22.4 26.6 26.4 69.9 27.5 18.5 29.2 26.2 21.1 25.1 43.9 21.9 20.9 29.9 20.7 25.5 29.4 65.8 19.0 16.6 24.7 19.4 23.1 23.5 15.9 23.2 35.6 27.3 18.1 49.3 13.9 26.0 19.0 27.2 26.3 38.6 46.4 54.7 26.9 36.3 32.2 21.5 33.9 46.9 55.7 45.9 33.8 32.4 44.2 18.2 50.9 44.4 22.3 49.8 40.5 55.3 17.4 44.7 32.6 36.0 149.2 45.0 28.0 24.8 35.3 32.4 40.1 34.9 54.1 110.4 44.2 40.1 40.3 37.2 41.2 50.9 25.8 13.8 65.7 41.2 41.0 70.9 32.8 42.7 43.8 31.1 51.0 37.4 37.4 77.8 60.9 61.3 32.5 42.3 63.9 46.8 38.2 42.4 27.0 18.2 31.2 28.4 25.5 27.7 18.3 16.4 22.1 16.4 14.5 17.3 17.2 16.4 15.7 14.2 13.6 13.8 13.4 5.3 19.1 14.1 14.1 24.6 13.4 24.2 24.3 25.1 29.3 22.4 26.6 29.2 26.2 29.9 23.5 27.3 26.3 37.7 0.0 14.2 25.5 18.2 13.0 33.3 42.6 16.5 33.9 34.7 40.6 17.3 38.6 25.0 14.7 35.5 49.4 23.5 21.2 49.0 60.6 32.3 26.2 25.8 43.6 15.7 13.2 29.5 29.6 65.0 21.3 23.9 40.9 20.3 70.3 20.7 38.5 29.9 60.6 52.9 26.0 44.7 18.9 21.3 27.5 29.2 21.9 32.0 15.9 64.2 129.4 18.6 24.6 27.7 38.8 18.7 46.3 16.8 25.1 26.3 27.9 32.5 40.4 59.2 25.7 30.8 118.0 97.7 24.8 14.6 30.6 24.2 19.2 34.3 22.3 PRR12 KIAA1205 ENSG00000126464 "Proline rich 12" Q9ULL5 19 49591182-49626439 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011959 Approved Approved Cytosol NA NA "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 59: Non-specific - Transcription" Cytosol "HPA011959: AB_10610286" "unprognostic (8.30e-2)" "unprognostic (8.64e-2)" "unprognostic (5.20e-3)" "unprognostic (5.04e-2)" "unprognostic (2.59e-1)" "unprognostic (1.05e-2)" "unprognostic (4.40e-3)" "unprognostic (5.00e-2)" "unprognostic (1.59e-1)" "unprognostic (1.25e-2)" "unprognostic (3.52e-3)" "unprognostic (8.59e-2)" "unprognostic (6.18e-2)" "unprognostic (2.00e-2)" "unprognostic (2.76e-1)" "unprognostic (9.32e-2)" "unprognostic (9.65e-3)" 11.6 12.6 8.8 7.2 6.5 5.4 11.8 7.6 11.3 15.1 0.0 14.2 6.2 16.7 2.0 12.3 14.3 3.1 11.0 7.6 4.0 10.1 6.9 10.2 7.8 4.4 3.0 16.3 11.3 4.7 22.9 4.6 1.7 13.0 2.2 4.5 13.0 7.4 14.8 21.3 12.7 3.5 0.9 14.8 12.8 7.5 2.8 7.5 15.7 3.4 4.2 14.0 13.1 2.6 15.4 23.4 12.6 14.0 5.6 5.0 10.0 9.5 4.6 5.2 4.1 9.0 8.9 15.5 7.9 6.8 4.9 14.0 5.8 8.3 1.7 13.2 17.3 16.0 12.4 9.0 4.0 15.1 23.0 6.4 8.2 5.9 3.9 6.3 5.8 9.2 11.1 8.9 4.6 11.6 17.1 18.2 17.9 7.8 21.5 22.2 9.8 5.8 4.7 19.0 10.0 18.6 13.8 12.8 6.7 5.0 9.0 11.0 13.9 18.0 17.2 6.8 15.7 11.4 14.4 10.4 11.2 8.6 11.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 8.8 6.5 7.6 11.3 7.6 4.0 4.4 3.0 1.7 0.9 2.8 2.6 8.8 6.4 2.6 9.8 8.1 4.0 1.3 8.2 8.6 7.7 8.1 6.5 2.9 7.2 3.6 12.9 4.2 5.5 8.7 5.8 1.9 4.1 1.1 5.1 8.8 5.5 10.2 2.5 9.3 7.5 3.3 5.6 8.6 7.1 10.2 9.6 6.8 2.9 6.4 5.0 11.9 6.6 4.1 7.5 2.8 2.1 14.0 5.8 3.6 8.4 3.3 3.6 5.2 10.6 8.8 13.4 5.7 14.7 6.0 1.9 6.6 2.5 6.5 3.6 13.1 7.3 5.5 2.7 6.8 6.9 7.7 1.1 7.5 6.9 6.9 1.5 PRR15L "ATAD4, MGC11242" ENSG00000167183 "Proline rich 15 like" Q9BU68 17 47951967-47957883 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 178.4;pancreas: 103.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 203.0;Distal tubular cells: 170.2;Intestinal goblet cells: 127.8;Paneth cells: 226.4;Proximal enterocytes: 263.7;Undifferentiated cells: 100.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "OE19: 205.6" "Not detected" "Not detected" HPA022918 Approved Approved Cytosol No NA "Cluster 15: NK-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Cytosol "HPA022918: AB_2060743" "unprognostic (9.91e-2)" "unprognostic (4.77e-2)" "unprognostic (8.18e-2)" "unprognostic (5.75e-3)" "unprognostic (1.83e-1)" "unprognostic (2.31e-2)" "unprognostic (2.48e-1)" "unprognostic (5.22e-2)" "unprognostic (2.86e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (8.32e-2)" "prognostic favorable (6.29e-13)" "prognostic favorable (1.69e-5)" "unprognostic (1.36e-1)" "unprognostic (8.26e-2)" "unprognostic (3.34e-2)" 2.2 0.1 0.0 7.9 0.1 0.1 38.8 0.2 0.2 13.4 9.5 111.2 178.4 1.4 18.3 12.9 26.5 22.0 0.4 0.8 0.0 28.0 1.9 21.7 0.2 0.1 0.0 0.3 103.9 0.8 8.5 0.0 0.0 17.7 124.3 0.0 51.8 15.8 0.1 10.0 128.5 3.3 0.0 0.0 84.4 2.5 0.0 0.4 67.8 0.0 2.0 2.7 6.7 0.1 3.8 0.6 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 8.6 5.8 0.2 0.3 0.0 0.0 20.5 0.0 0.1 0.0 0.4 0.7 0.2 0.0 2.6 0.0 0.4 0.4 0.0 4.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 19.7 0.4 0.4 0.0 205.6 0.7 0.3 0.0 1.4 1.1 2.6 11.7 0.5 0.0 35.7 0.0 0.0 24.1 0.0 0.1 0.3 0.0 0.7 0.1 0.1 0.1 0.3 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 22.4 19.8 0.3 0.1 0.0 2.6 2.4 0.0 0.0 16.7 8.9 0.1 80.1 19.8 16.5 0.0 0.0 0.1 203.0 170.2 35.6 5.5 9.8 0.3 0.2 31.6 0.0 0.1 36.1 0.0 0.4 55.5 3.9 0.0 0.0 0.0 0.8 0.1 0.0 0.1 127.8 24.4 0.0 0.0 9.0 1.2 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 11.6 226.4 0.4 0.2 15.6 263.7 30.0 19.2 0.0 0.0 0.0 1.0 11.1 0.1 7.3 0.0 0.0 0.6 0.0 100.9 9.9 PRRC2C "BAT2D1, BAT2L2, KIAA1096, XTP2" ENSG00000117523 "Proline rich coiled-coil 2C" Q9Y520 1 171485551-171593511 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025766, HPA028659" Approved Enhanced Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Cytosol "HPA025766: AB_1845277, HPA028659: AB_10600786" "unprognostic (4.16e-1)" "unprognostic (2.40e-2)" "unprognostic (6.66e-3)" "unprognostic (8.71e-2)" "unprognostic (6.07e-3)" "unprognostic (1.85e-1)" "unprognostic (2.74e-2)" "unprognostic (1.63e-1)" "unprognostic (1.39e-2)" "unprognostic (2.28e-1)" "unprognostic (8.19e-3)" "unprognostic (5.56e-2)" "prognostic unfavorable (7.76e-6)" "unprognostic (7.03e-2)" "unprognostic (2.62e-1)" "unprognostic (1.82e-1)" "unprognostic (4.34e-2)" 30.9 21.0 26.8 33.3 25.8 72.5 32.7 32.1 35.0 34.0 19.0 27.0 21.6 30.2 37.5 36.7 29.7 26.2 22.7 22.9 34.2 28.8 31.1 35.8 44.8 27.5 27.1 34.3 28.9 33.8 25.7 34.2 27.6 28.2 31.9 34.5 30.3 27.1 25.7 39.7 34.0 25.4 20.3 36.0 28.9 29.3 26.4 49.6 27.8 23.7 43.4 38.5 34.4 30.7 84.9 64.3 88.1 58.4 61.0 70.5 65.2 47.8 67.7 54.8 49.7 99.1 59.0 123.9 73.1 70.4 44.3 73.8 96.5 76.1 83.8 70.1 51.4 94.2 51.2 69.5 63.3 154.4 73.8 68.6 57.1 92.7 137.3 49.3 80.9 66.6 126.8 66.6 63.0 40.3 92.8 65.2 116.8 67.5 110.5 69.3 65.5 60.7 77.8 93.3 56.7 58.3 72.6 85.4 56.0 115.8 58.2 107.0 101.6 61.9 57.0 60.7 100.4 55.5 63.4 175.3 39.4 74.7 56.7 2.2 1.3 0.7 1.3 1.2 1.3 1.7 1.2 1.2 0.6 2.0 1.1 1.3 3.4 2.5 1.4 2.0 1.0 0.6 26.8 25.8 32.1 35.0 22.9 34.2 27.5 27.1 27.6 20.3 26.4 30.7 233.8 298.1 224.7 81.0 272.5 167.0 270.8 107.5 198.6 164.6 105.4 104.6 115.7 133.0 198.3 86.5 139.7 204.0 325.0 190.0 25.4 174.0 63.9 228.0 246.7 214.5 165.1 139.0 101.5 151.3 210.1 189.1 157.0 378.3 263.2 132.8 130.3 119.0 128.9 138.0 108.6 162.3 57.0 142.8 183.0 36.5 139.1 211.0 96.0 91.8 227.9 120.4 269.8 87.9 143.2 223.1 145.2 96.3 281.8 294.3 99.6 40.1 132.1 170.4 78.9 218.1 184.2 247.7 160.8 178.0 145.9 476.8 317.3 178.5 168.5 335.5 PRSS21 "ESP-1, TEST1" ENSG00000007038 "Serine protease 21" Q9Y6M0 16 2817180-2826304 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 84.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 84.1;Early spermatids: 111.0;Late spermatids: 349.7;Spermatocytes: 453.2;Spermatogonia: 270.2" "Cancer enhanced" "Detected in many" "ovarian cancer: 23.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "basophil: 16.1;eosinophil: 33.0" "Lineage enriched" "Detected in all" 7 "granulocytes: 33.0" "Cell line enhanced" "Detected in some" "CAPAN-2: 25.0;HEL: 28.5;HeLa: 71.0;K-562: 34.3;U-698: 104.8" "Not detected" "Not detected" "Region enriched" "Detected in single" 38 "basal ganglia: 8.9" HPA008477 Enhanced Approved Cytosol "Intracellular and membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol "HPA008477: AB_1079697" "unprognostic (4.35e-2)" "unprognostic (3.46e-2)" "unprognostic (7.06e-2)" "unprognostic (4.28e-3)" "unprognostic (1.19e-3)" "unprognostic (7.02e-2)" "unprognostic (1.22e-1)" "unprognostic (2.61e-2)" "unprognostic (2.33e-1)" "unprognostic (5.21e-2)" "unprognostic (8.83e-3)" "unprognostic (1.52e-3)" "unprognostic (2.97e-2)" "unprognostic (1.14e-2)" "unprognostic (5.07e-2)" "unprognostic (7.79e-2)" "unprognostic (2.99e-1)" 0.1 0.0 0.1 0.5 0.1 7.8 1.3 0.0 0.1 1.6 0.0 0.7 0.5 0.2 0.0 1.5 2.7 1.8 0.0 0.0 0.1 0.1 0.1 2.5 1.2 0.1 0.0 0.1 2.0 1.5 0.1 0.0 0.1 3.8 0.5 0.0 20.5 0.3 0.0 0.9 0.8 0.1 0.0 1.7 0.8 84.6 0.1 1.1 0.0 0.0 1.2 0.4 1.4 0.1 11.3 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 25.0 0.0 0.1 0.8 0.0 1.0 0.0 0.0 0.0 0.0 0.0 28.5 71.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.3 0.0 0.0 0.0 0.0 13.8 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 104.8 0.0 0.0 0.0 16.1 3.5 33.0 3.1 2.6 4.8 1.2 1.5 2.6 0.9 0.8 2.2 3.2 0.3 1.8 0.5 2.2 1.0 2.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 4.6 1.1 37.9 9.4 13.1 0.0 6.1 8.4 84.1 0.0 2.7 0.0 0.0 0.3 2.1 1.4 0.0 1.1 111.0 0.3 2.6 1.6 0.0 9.7 0.0 0.4 9.0 0.7 0.0 0.4 0.0 0.4 0.0 0.0 11.1 0.0 0.0 1.5 4.1 0.6 0.7 349.7 6.5 5.7 0.0 0.0 1.1 0.0 4.1 0.0 0.1 0.7 0.6 3.8 20.4 32.7 0.1 0.1 0.5 0.0 46.0 0.0 1.0 453.2 270.2 2.8 0.6 0.1 3.4 0.0 2.4 14.5 PRUNE1 "DRES-17, H-PRUNE, HTCD37, PRUNE" ENSG00000143363 "Prune exopolyphosphatase 1" Q86TP1 1 151008420-151035713 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Mental retardation, Neurodegeneration, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 13.0;Breast glandular cells: 9.8;Breast myoepithelial cells: 8.9;Collecting duct cells: 11.0;Granulosa cells: 8.9;Proximal tubular cells: 8.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 169.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028411 Uncertain Supported Cytosol NA NA 41000 "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA028411: AB_10603229" "unprognostic (6.24e-2)" "unprognostic (2.24e-1)" "unprognostic (4.17e-2)" "prognostic unfavorable (3.86e-4)" "unprognostic (6.91e-2)" "unprognostic (2.02e-1)" "unprognostic (2.12e-3)" "unprognostic (7.05e-2)" "unprognostic (4.08e-2)" "unprognostic (5.92e-2)" "unprognostic (1.73e-1)" "unprognostic (2.65e-1)" "prognostic unfavorable (3.48e-4)" "unprognostic (2.18e-1)" "unprognostic (3.21e-2)" "unprognostic (2.42e-2)" "unprognostic (1.36e-1)" 10.1 9.5 12.2 7.7 12.1 4.4 14.9 16.1 15.1 15.0 12.4 14.8 12.5 14.8 15.6 12.4 16.0 9.2 33.4 12.4 12.6 18.8 14.3 10.8 10.8 12.0 12.5 17.2 10.7 20.9 12.6 7.1 11.9 12.2 14.5 10.8 13.2 14.4 29.4 11.5 12.0 14.1 11.9 11.2 11.2 18.3 12.8 16.2 32.5 21.4 12.6 13.7 11.9 13.5 11.0 11.6 20.2 19.3 24.3 6.6 10.9 5.1 11.2 18.7 16.4 14.1 13.0 22.2 21.7 6.9 5.5 15.5 19.9 13.4 14.6 24.5 22.6 26.6 11.8 20.4 13.5 17.5 13.0 8.4 24.7 10.2 9.5 15.4 9.2 29.4 21.1 18.3 8.9 26.2 27.2 14.1 18.7 39.7 15.0 24.2 12.8 21.5 13.4 14.9 28.7 23.5 17.5 23.5 16.1 28.3 32.6 25.7 6.3 6.6 7.8 7.5 8.1 44.1 40.0 169.1 6.5 13.0 16.9 19.1 8.1 17.8 16.4 7.8 19.8 14.4 18.1 18.6 11.9 15.4 21.7 17.5 18.6 18.8 12.2 6.4 18.5 22.3 12.2 12.1 16.1 15.1 12.4 12.6 12.0 12.5 11.9 11.9 12.8 13.5 4.5 6.4 13.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 9.8 8.9 0.0 0.0 3.1 11.0 0.0 4.1 3.2 0.0 0.0 6.0 0.0 4.3 7.8 2.1 0.0 0.0 0.0 5.7 4.8 2.5 0.0 6.4 0.0 8.9 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 5.6 0.0 0.0 1.0 0.0 0.0 8.9 2.9 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 5.1 2.8 4.8 0.0 0.0 PSAPL1 ENSG00000178597 "Prosaposin like 1" Q6NUJ1 4 7430285-7434930 "Predicted secreted proteins" "Lipid metabolism, Sphingolipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "skin 1: 98.5;stomach 1: 38.6" "Cell type enriched" "Detected in some" 13 "Gastric mucus-secreting cells: 41.8" "Group enriched" "Detected in some" 5 "head and neck cancer: 0.7;melanoma: 2.5;pancreatic cancer: 2.0;stomach cancer: 3.0;urothelial cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "CACO-2: 16.6;OE19: 32.2;RPMI-8226: 24.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038013, HPA038482" Approved Enhanced Cytosol "Secreted - unknown location" NA NA 31000 "Cluster 61: Skin - Cornification" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "HPA038013: AB_10673652, HPA038482: AB_2676037" "unprognostic (2.64e-2)" "unprognostic (2.40e-1)" "unprognostic (9.33e-2)" "unprognostic (2.40e-1)" "unprognostic (2.61e-1)" "unprognostic (7.90e-3)" "unprognostic (2.52e-1)" "unprognostic (2.08e-2)" "unprognostic (2.75e-1)" "unprognostic (2.63e-3)" 0.3 0.0 0.0 0.0 0.3 0.0 4.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 98.5 0.0 0.0 0.0 0.0 38.6 3.4 0.1 0.2 0.0 0.0 3.1 0.0 0.2 0.7 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 16.6 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.2 0.0 0.0 0.0 24.7 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.7 0.0 0.0 0.0 0.3 0.2 0.1 0.0 1.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 41.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 PSAT1 PSA ENSG00000135069 "Phosphoserine aminotransferase 1" Q9Y617 9 78297125-78330093 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Serine biosynthesis" "Aminotransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 175.0;liver: 267.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 115.5;Glandular and luminal cells: 145.9;Hepatocytes: 161.7;Proximal tubular cells: 304.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 15.1" "Lineage enriched" "Detected in many" 5 "T-cells: 15.1" "Cell line enhanced" "Detected in many" "hTCEpi: 1170.1;SK-MEL-30: 752.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014882, CAB040567, HPA042924" Enhanced Enhanced Cytosol NA NA 2400000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 22: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "CAB014882: , CAB040567: , HPA042924: AB_2678223" "unprognostic (8.26e-3)" "unprognostic (4.69e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (5.62e-5)" "unprognostic (4.05e-3)" "unprognostic (1.41e-1)" "unprognostic (2.21e-3)" "unprognostic (1.86e-1)" "unprognostic (9.85e-2)" "unprognostic (2.25e-2)" "unprognostic (4.53e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (6.00e-7)" "unprognostic (3.87e-3)" "unprognostic (1.21e-1)" "unprognostic (8.07e-3)" "unprognostic (1.71e-1)" 7.8 65.8 123.3 7.3 124.6 2.0 5.1 130.5 175.0 5.1 92.8 5.9 5.4 4.3 61.6 33.2 34.7 1.7 2.7 122.4 126.5 136.7 267.9 5.1 9.3 130.2 122.4 5.6 129.1 9.7 7.6 3.0 129.9 10.0 5.5 6.2 19.2 4.0 0.6 57.2 4.5 3.3 133.6 6.0 19.4 10.4 120.3 30.0 30.3 0.5 12.4 7.3 11.2 161.6 222.8 146.0 121.1 215.6 35.1 41.2 284.7 184.3 130.4 91.8 170.6 38.2 41.9 143.2 79.8 416.9 82.9 215.3 209.1 203.6 136.4 141.2 73.9 49.2 60.8 293.3 322.0 277.6 84.6 131.1 1170.1 122.0 322.9 22.6 85.0 548.3 53.8 358.2 77.1 83.2 95.8 44.3 278.2 415.1 158.4 46.5 78.6 173.4 126.6 50.9 54.9 127.0 51.1 87.7 752.3 75.9 42.0 344.1 19.9 23.2 73.5 85.9 151.5 242.0 242.7 0.8 268.9 215.6 112.1 0.0 0.0 0.0 5.2 0.0 5.9 3.1 5.0 7.0 0.3 1.3 8.1 7.5 0.3 0.0 0.1 0.0 15.1 3.3 123.3 124.6 130.5 175.0 122.4 126.5 130.2 122.4 129.9 133.6 120.3 161.6 0.4 0.0 0.0 70.2 11.0 41.9 8.8 18.9 115.5 0.9 1.8 3.9 0.6 1.5 4.7 11.0 0.0 32.0 2.2 2.0 62.6 11.5 1.7 77.7 10.3 3.7 3.6 29.9 7.3 48.4 13.7 4.2 6.6 145.9 0.0 0.5 3.6 161.7 5.3 5.0 6.0 4.8 18.3 4.4 2.9 3.8 5.0 3.4 19.6 5.6 3.8 26.7 0.0 48.2 78.8 22.7 0.1 1.9 29.1 16.0 0.3 304.1 3.8 1.1 0.0 33.5 14.3 1.6 3.7 35.5 50.7 9.3 8.6 68.2 4.2 11.8 PSMA5 ZETA ENSG00000143106 "Proteasome 20S subunit alpha 5" P28066 1 109399042-109426448 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 54.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028392, HPA028398, HPA028441" Approved Supported Cytosol NA NA 20000000 "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA028392: AB_10600115, HPA028398: AB_10602310, HPA028441: AB_10602003" "unprognostic (3.82e-2)" "unprognostic (3.09e-3)" "prognostic favorable (1.45e-5)" "unprognostic (1.57e-1)" "unprognostic (2.71e-1)" "unprognostic (1.52e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (5.95e-2)" "unprognostic (1.71e-2)" "unprognostic (1.13e-3)" "unprognostic (4.20e-3)" "unprognostic (3.05e-1)" "unprognostic (1.07e-3)" "unprognostic (3.99e-2)" "unprognostic (2.34e-1)" "unprognostic (8.81e-3)" "unprognostic (1.05e-1)" 3.5 4.7 5.1 4.3 6.2 3.8 6.8 4.0 7.7 5.8 2.7 7.4 7.5 5.5 8.6 6.8 9.1 5.4 7.7 6.8 6.7 10.9 20.2 5.9 12.7 5.0 4.7 5.2 3.2 5.9 1.4 6.9 4.5 5.4 8.5 4.8 5.0 6.2 6.1 6.2 6.7 6.5 4.1 4.8 5.2 3.5 5.3 6.4 10.2 5.1 9.3 6.1 0.9 6.6 10.1 11.7 6.2 5.7 17.6 16.9 12.6 4.9 29.8 23.2 17.9 15.0 5.5 28.1 7.8 21.2 4.2 5.7 13.8 13.7 16.1 10.7 13.1 13.4 7.7 12.4 14.0 15.2 5.3 8.5 12.3 12.7 14.3 6.2 15.0 8.2 17.1 6.5 12.4 18.6 54.4 10.3 5.7 7.0 16.5 4.4 16.9 7.4 19.0 11.5 7.3 5.2 10.5 16.2 8.9 5.0 5.9 14.1 11.7 4.6 4.6 7.9 10.3 3.6 11.6 19.7 20.0 26.0 7.4 11.0 4.3 3.1 7.7 6.3 8.4 5.7 9.0 8.3 5.9 4.7 9.7 9.7 1.4 7.2 6.1 4.2 11.4 7.0 5.1 6.2 4.0 7.7 6.8 6.7 5.0 4.7 4.5 4.1 5.3 6.6 68.9 41.7 56.8 9.4 77.4 63.6 73.5 231.0 38.1 32.6 59.5 75.7 89.5 75.8 120.9 42.3 6.2 227.0 114.5 82.1 140.8 164.9 82.0 157.6 74.1 71.6 56.3 85.0 21.7 183.0 181.4 60.4 74.9 81.9 82.4 77.7 51.4 117.4 166.9 13.5 18.4 144.1 168.9 57.8 73.6 23.4 67.7 86.3 58.7 15.0 184.8 50.2 114.4 13.0 20.2 191.6 103.5 62.1 113.1 122.2 138.0 205.6 172.4 31.7 46.0 56.1 182.6 120.3 89.1 70.4 65.9 241.2 106.1 121.4 135.3 104.2 PSMB9 "beta1i, LMP2, PSMB6i, RING12" ENSG00000240065 "Proteasome 20S subunit beta 9" P28065 6 32844136-32859851 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Immunity" "Hydrolase, Protease, Threonine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 160.9" "Cell type enhanced" "Detected in many" "monocytes: 323.0;NK-cells: 495.4;Proximal enterocytes: 318.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 27.7;Daudi: 40.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015180, HPA042818, HPA053280" Enhanced Supported Cytosol NA NA 340000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "CAB015180: AB_2172368, HPA042818: AB_2678186, HPA053280: AB_2682098" "unprognostic (1.09e-2)" "unprognostic (1.68e-2)" "unprognostic (1.26e-2)" "unprognostic (2.18e-3)" "unprognostic (7.84e-2)" "unprognostic (1.89e-1)" "unprognostic (5.68e-2)" "unprognostic (6.67e-2)" "unprognostic (1.56e-2)" "unprognostic (6.50e-3)" "unprognostic (1.87e-3)" "unprognostic (1.84e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (2.65e-1)" "unprognostic (1.09e-1)" "unprognostic (4.96e-3)" "unprognostic (5.99e-2)" 47.0 31.1 4.8 18.4 4.9 6.9 41.4 4.3 5.5 28.8 2.6 38.4 10.2 26.8 2.3 25.7 25.9 4.7 31.6 4.8 5.6 36.3 37.4 60.2 26.2 7.6 4.9 18.1 12.1 1.5 14.0 3.4 5.9 26.5 8.7 1.3 20.3 5.0 11.9 27.7 78.1 5.7 5.7 160.9 26.5 4.9 5.1 15.0 28.7 3.8 22.2 23.6 30.8 5.8 5.5 0.3 0.0 0.2 3.4 8.5 3.0 0.7 11.5 17.3 27.7 0.0 3.1 40.8 1.3 2.9 14.3 10.0 0.2 5.8 2.6 9.3 0.1 17.6 0.7 0.8 17.3 1.8 2.2 2.1 0.3 7.0 1.0 3.3 2.7 10.1 1.4 12.8 1.9 1.0 16.1 8.0 0.0 0.0 0.8 19.0 1.2 7.4 2.1 2.5 0.0 0.0 1.0 2.1 10.7 0.0 4.4 10.3 0.0 2.5 1.6 14.7 1.2 11.3 23.9 9.3 7.5 6.8 4.0 92.7 30.3 75.6 56.1 55.8 45.9 59.7 45.1 55.9 26.6 45.3 41.0 49.6 96.3 61.5 60.9 20.5 61.0 46.2 4.8 4.9 4.3 5.5 4.8 5.6 7.6 4.9 5.9 5.7 5.1 5.8 258.6 41.7 51.1 1.3 197.2 72.5 37.4 155.6 30.1 2.4 25.3 47.0 7.3 50.1 64.8 25.8 0.0 1.5 216.2 88.0 19.6 116.6 1.3 28.9 47.5 146.5 33.5 29.9 0.0 115.6 6.6 45.1 34.1 42.6 77.3 20.0 119.6 26.6 117.2 0.0 0.1 148.0 99.7 126.8 155.7 2.1 29.2 145.2 35.6 8.4 323.0 22.7 495.4 0.5 8.3 67.8 150.3 15.8 136.1 40.4 318.5 40.5 133.7 1.7 32.9 23.1 50.8 1.5 7.4 21.0 58.7 1.4 241.8 45.3 110.6 39.1 PSMF1 PI31 ENSG00000125818 "Proteasome inhibitor subunit 1" Q92530 20 1113240-1189415 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 15 "Early spermatids: 1242.7;Late spermatids: 4603.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041122, HPA041300" Approved Enhanced Cytosol NA NA 160000 "Cluster 2: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 39: CACO-2 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA041122: AB_10805838, HPA041300: AB_10794370" "unprognostic (1.79e-2)" "unprognostic (8.96e-2)" "unprognostic (7.22e-2)" "unprognostic (3.88e-2)" "unprognostic (1.68e-3)" "unprognostic (1.43e-2)" "unprognostic (9.14e-3)" "unprognostic (1.56e-1)" "unprognostic (7.03e-2)" "unprognostic (4.71e-1)" "unprognostic (2.45e-1)" "unprognostic (7.41e-2)" "unprognostic (3.72e-3)" "unprognostic (1.10e-1)" "unprognostic (1.36e-1)" "unprognostic (4.18e-2)" "unprognostic (8.32e-2)" 49.7 37.8 32.8 41.8 33.8 53.7 43.4 33.5 35.7 44.3 33.2 46.0 44.2 42.5 27.8 47.7 37.8 26.8 52.0 31.5 33.0 42.4 72.6 43.4 40.9 35.7 33.2 43.8 56.8 43.1 35.2 26.3 34.2 33.3 31.7 32.9 38.8 32.5 128.3 47.2 42.9 36.9 32.8 38.3 44.0 107.6 36.7 41.2 37.7 83.6 39.9 42.3 39.1 35.5 141.5 126.4 29.7 70.3 63.8 66.5 50.8 83.8 64.9 76.1 67.2 118.2 96.4 71.2 56.1 90.3 79.3 123.8 78.9 143.3 95.1 42.3 47.0 99.1 20.8 217.0 83.7 120.6 33.2 67.9 82.3 85.3 132.7 45.9 83.2 55.3 101.5 138.8 62.9 75.4 156.3 107.9 42.6 81.4 79.2 74.5 62.2 118.6 67.7 117.9 75.4 52.4 92.3 159.1 77.3 28.5 108.8 43.3 96.8 95.3 63.8 111.3 115.6 85.9 185.5 77.5 41.8 81.3 74.7 123.8 65.2 123.3 49.8 80.2 57.8 73.2 66.2 54.4 66.3 69.0 59.7 52.8 71.7 58.5 83.0 37.8 81.6 69.4 32.8 33.8 33.5 35.7 31.5 33.0 35.7 33.2 34.2 32.8 36.7 35.5 48.7 35.3 44.2 34.0 58.3 41.2 59.1 81.0 33.0 32.7 40.5 41.5 55.4 31.5 44.8 40.5 4.2 68.0 48.8 51.9 82.2 102.5 1242.7 27.3 38.4 47.4 67.4 190.1 25.2 103.8 88.9 50.2 48.4 28.1 49.5 46.5 50.0 70.0 100.3 21.9 25.4 57.9 34.6 56.3 56.7 4603.4 77.3 58.2 51.6 34.7 76.1 64.3 55.6 22.1 38.1 99.4 75.3 88.8 66.8 69.0 103.3 80.7 32.4 33.1 118.3 36.7 65.0 97.4 90.7 52.1 48.6 74.0 55.0 73.0 62.6 68.8 PSPH PSP ENSG00000146733 "Phosphoserine phosphatase" P78330 7 56011051-56051604 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Serine biosynthesis" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 107.6;Early spermatids: 149.8;Late spermatids: 211.5;Proximal tubular cells: 91.7" "Cancer enhanced" "Detected in all" "glioma: 41.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020376, HPA029515" Approved Approved Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" Cytosol "HPA020376: AB_1855867, HPA029515: AB_10601492" "prognostic unfavorable (2.30e-4)" "unprognostic (7.80e-2)" "unprognostic (1.55e-1)" "unprognostic (2.03e-1)" "unprognostic (1.07e-1)" "unprognostic (7.66e-3)" "prognostic unfavorable (2.75e-5)" "unprognostic (1.74e-1)" "unprognostic (2.13e-1)" "unprognostic (4.45e-2)" "prognostic favorable (3.77e-4)" "unprognostic (3.78e-2)" "unprognostic (5.74e-2)" "unprognostic (2.64e-1)" "unprognostic (3.01e-2)" "unprognostic (1.90e-3)" "unprognostic (9.05e-3)" 4.7 9.4 11.0 3.7 12.4 3.7 3.9 11.8 10.8 4.7 13.3 4.8 4.2 4.9 5.2 8.7 16.1 5.9 8.1 11.0 11.0 10.0 6.8 3.5 5.1 12.3 12.9 8.2 6.7 6.6 9.4 3.7 11.7 6.4 4.4 4.4 4.5 6.4 4.6 4.2 4.1 5.1 12.2 3.9 6.2 7.1 12.1 5.8 7.0 6.0 5.9 5.2 5.7 16.1 130.1 37.6 23.1 93.0 18.9 25.3 16.7 32.5 18.5 18.7 32.7 34.7 23.5 62.9 21.0 29.4 44.5 26.9 52.6 26.9 19.0 48.1 27.9 17.9 11.1 62.2 44.4 18.6 26.8 31.8 50.2 27.7 32.6 25.1 17.7 61.2 44.4 42.4 26.4 17.3 27.7 48.3 38.0 47.5 52.1 35.9 14.4 39.8 17.2 6.8 43.6 49.8 23.5 14.9 68.9 20.9 44.8 41.4 14.5 15.1 24.8 45.5 30.3 26.9 53.0 72.8 21.9 39.9 49.7 2.5 6.2 5.9 3.1 4.4 2.3 5.4 3.0 3.8 9.6 6.1 4.5 4.1 2.9 4.7 7.1 9.3 4.0 4.8 11.0 12.4 11.8 10.8 11.0 11.0 12.3 12.9 11.7 12.2 12.1 16.1 2.1 3.2 1.5 11.4 5.2 6.8 16.9 20.5 8.6 5.2 8.3 5.8 13.1 11.5 11.4 5.5 2.1 12.8 4.5 2.4 107.6 8.6 149.8 62.9 5.4 4.2 4.8 7.2 9.3 8.0 7.5 9.9 3.1 9.4 1.3 16.5 5.0 9.8 9.5 1.7 9.8 5.0 4.1 4.4 5.8 211.5 8.4 4.3 7.2 0.0 5.7 46.8 2.1 7.1 13.8 7.1 3.5 6.0 10.1 6.5 3.1 91.7 28.3 3.1 13.1 5.1 20.0 30.1 22.5 7.6 8.5 4.7 3.9 16.1 7.3 7.7 PTPRQ DFNB84 ENSG00000139304 "Protein tyrosine phosphatase receptor type Q" 12 80402178-80680273 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "kidney: 7.1;urinary bladder: 4.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 16.0;Club cells: 4.4;Early spermatids: 10.9;Excitatory neurons: 11.2;Late spermatids: 4.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 4.9;BJ: 3.9;HBF TERT88: 2.6;RH-30: 2.9;RT4: 3.4;SiHa: 1.9;U-2197: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA053245 Uncertain Approved Cytosol No NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA053245: AB_2682087" "unprognostic (9.10e-2)" "unprognostic (1.63e-1)" "unprognostic (1.15e-1)" "unprognostic (3.30e-2)" "unprognostic (1.37e-1)" "unprognostic (1.93e-2)" "unprognostic (1.04e-2)" "unprognostic (1.46e-1)" "unprognostic (1.80e-2)" "unprognostic (1.78e-1)" "unprognostic (4.47e-11)" "unprognostic (8.51e-3)" "unprognostic (1.47e-1)" "unprognostic (1.73e-2)" "unprognostic (2.66e-2)" 3.2 0.0 0.3 0.0 2.0 0.0 0.4 0.0 0.7 0.5 0.0 0.1 0.0 0.0 1.9 0.1 1.6 0.2 1.1 0.2 0.4 7.1 0.0 2.3 0.9 1.0 0.7 0.3 0.3 0.1 0.1 0.1 0.6 0.6 0.0 0.8 0.1 0.1 0.2 0.1 0.0 0.0 0.8 0.0 0.1 2.7 0.3 0.2 2.9 0.0 0.3 4.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 4.9 0.0 3.9 0.8 1.2 0.7 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.5 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 3.4 0.0 0.0 1.9 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.0 0.0 0.7 0.2 0.4 1.0 0.7 0.6 0.8 0.3 0.0 0.0 16.0 1.1 2.0 0.0 0.0 1.9 0.3 0.0 0.1 0.0 0.0 3.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 4.6 0.0 0.1 0.0 0.0 0.0 0.9 0.0 2.5 1.3 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.5 0.2 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 PTS PTPS ENSG00000150787 "6-pyruvoyltetrahydropterin synthase" Q03393 11 112226367-112269955 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" Lyase "Disease variant, Phenylketonuria" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001481 Uncertain Approved Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "HPA001481: AB_1079716" "unprognostic (2.08e-2)" "unprognostic (1.91e-1)" "unprognostic (9.66e-3)" "unprognostic (8.38e-3)" "unprognostic (4.58e-1)" "unprognostic (3.28e-3)" "unprognostic (2.38e-2)" "unprognostic (1.81e-2)" "unprognostic (2.05e-2)" "unprognostic (8.74e-2)" "unprognostic (2.59e-1)" "unprognostic (7.07e-2)" "unprognostic (3.81e-2)" "unprognostic (1.20e-2)" "unprognostic (2.97e-1)" "unprognostic (1.52e-3)" "unprognostic (1.65e-1)" 11.7 63.0 17.6 10.2 18.7 22.7 20.5 20.2 27.6 17.5 20.2 18.9 15.0 13.6 29.7 29.0 11.7 20.6 8.8 16.5 25.1 44.7 68.9 7.8 10.5 23.1 26.1 9.9 15.0 29.0 32.8 18.0 24.6 21.1 21.5 19.0 17.5 16.4 18.5 17.0 16.1 13.0 19.7 7.7 27.4 10.3 20.5 4.4 23.2 10.9 12.4 21.7 19.2 21.6 24.5 24.2 33.4 12.9 23.9 26.8 35.4 78.3 38.8 45.5 48.5 57.0 26.1 28.5 53.5 51.6 60.8 38.0 47.5 54.8 50.6 19.7 28.8 7.5 44.6 55.8 70.9 18.4 4.0 47.8 77.1 43.9 53.0 36.5 35.2 24.6 24.9 16.8 30.1 29.8 14.8 23.8 23.1 54.2 48.3 9.4 6.3 37.6 101.2 38.8 32.2 32.5 41.1 43.8 26.0 109.0 32.3 15.2 40.2 42.5 43.0 49.7 60.7 9.9 20.8 69.4 29.3 19.4 44.1 1.1 0.4 0.4 1.2 0.7 1.3 1.5 1.7 1.8 0.7 1.6 1.1 1.5 0.2 1.5 2.0 2.0 1.9 0.7 17.6 18.7 20.2 27.6 16.5 25.1 23.1 26.1 24.6 19.7 20.5 21.6 43.7 19.2 26.5 13.1 28.6 122.6 80.4 146.2 59.2 17.4 69.4 69.0 95.0 47.1 85.7 55.2 0.0 56.7 41.4 80.0 211.3 91.9 5.5 66.4 37.0 42.8 80.0 23.2 16.8 78.9 120.7 47.9 37.8 72.6 20.8 45.1 34.6 123.6 36.9 10.1 25.4 73.1 150.5 21.4 38.1 7.6 14.6 28.4 26.6 15.0 26.1 48.5 22.6 17.6 36.1 114.4 74.4 25.9 33.0 91.9 58.3 151.0 80.8 18.3 26.3 22.7 70.8 23.3 92.6 65.4 131.1 70.3 28.5 59.6 44.4 114.9 PUM2 "KIAA0235, PUMH2" ENSG00000055917 "Pumilio RNA binding family member 2" Q8TB72 2 20248691-20352234 "Predicted intracellular proteins" "Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030316, HPA049670" Approved Enhanced Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Cytosol "HPA030316: AB_10610289, HPA049670: AB_2680845" "unprognostic (2.41e-1)" "unprognostic (8.77e-2)" "unprognostic (1.97e-1)" "unprognostic (2.31e-2)" "unprognostic (9.89e-2)" "unprognostic (1.39e-2)" "prognostic unfavorable (5.67e-4)" "unprognostic (3.86e-2)" "unprognostic (1.23e-1)" "unprognostic (4.49e-3)" "unprognostic (1.05e-2)" "unprognostic (6.87e-2)" "unprognostic (1.10e-1)" "unprognostic (1.09e-1)" "unprognostic (2.41e-1)" "unprognostic (4.81e-2)" "unprognostic (2.87e-2)" 27.6 29.8 29.7 33.4 31.7 33.4 41.7 42.5 32.7 36.2 32.4 36.5 34.4 36.3 32.8 39.2 29.7 27.1 33.1 31.1 30.9 36.8 43.1 33.2 48.6 26.0 29.3 44.6 27.4 41.4 8.3 40.3 26.1 37.3 37.0 66.8 33.0 33.1 21.5 47.2 35.6 32.3 29.1 42.6 35.8 24.9 31.6 70.5 57.6 32.6 47.6 38.0 18.3 37.6 72.4 50.0 65.3 46.1 40.2 40.5 65.9 49.2 53.6 48.4 42.2 43.5 33.0 96.3 11.0 44.9 58.2 38.9 61.4 35.6 71.2 87.0 38.2 105.0 35.3 62.2 43.4 107.2 93.3 29.7 79.7 42.1 77.4 45.5 53.1 57.1 75.0 82.9 57.3 35.5 93.6 65.9 55.8 68.3 31.5 80.6 110.9 73.8 45.0 68.1 55.9 76.6 42.2 58.3 48.1 43.4 33.0 61.5 52.5 58.6 58.5 38.3 64.6 93.3 123.0 181.8 35.3 75.8 51.4 11.5 4.0 5.8 6.0 5.2 7.1 4.8 6.7 7.5 4.2 5.3 7.3 6.0 11.6 7.7 7.3 3.7 5.8 3.7 29.7 31.7 42.5 32.7 31.1 30.9 26.0 29.3 26.1 29.1 31.6 37.6 43.6 35.3 51.6 89.5 57.6 79.7 32.2 26.4 74.0 94.6 46.9 30.5 46.5 32.9 33.8 47.8 62.6 36.3 43.6 44.0 11.7 16.6 10.1 33.9 35.6 45.0 34.6 41.0 134.7 15.5 16.9 36.5 43.8 45.9 20.3 53.0 41.4 56.3 29.1 58.9 153.5 43.2 38.7 70.7 44.2 5.8 34.2 44.9 32.0 144.3 42.7 26.8 43.3 155.3 186.0 22.6 28.1 26.4 54.7 57.8 33.9 29.7 39.5 72.3 32.9 40.5 47.6 16.8 16.6 75.2 106.3 52.0 50.1 31.2 40.2 56.6 PYGB ENSG00000100994 "Glycogen phosphorylase B" P11216 20 25248085-25298012 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Allosteric enzyme, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 122.8;Distal enterocytes: 185.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 407.8;SK-MEL-30: 528.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031067 Approved Approved Cytosol NA NA 14000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA031067: AB_2673722" "unprognostic (6.13e-2)" "unprognostic (5.98e-2)" "unprognostic (1.21e-1)" "unprognostic (2.22e-1)" "unprognostic (1.21e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.37e-4)" "prognostic unfavorable (1.10e-4)" "unprognostic (1.23e-3)" "unprognostic (8.39e-3)" "unprognostic (1.58e-3)" "unprognostic (1.98e-1)" "unprognostic (1.22e-2)" "unprognostic (3.41e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.43e-4)" 50.8 36.4 78.2 27.7 77.9 14.1 61.1 84.1 82.4 37.0 35.4 140.9 27.0 51.9 21.4 106.6 37.8 39.1 163.9 77.3 74.9 43.7 14.6 32.1 19.1 85.4 80.8 25.9 25.4 18.1 61.5 11.5 81.2 107.9 72.6 25.4 125.1 106.3 18.7 85.3 44.8 59.8 84.7 22.6 51.3 25.2 80.3 18.4 45.2 10.5 17.3 154.2 53.0 84.8 31.5 220.1 39.1 38.3 97.9 182.7 28.7 62.2 80.9 51.4 43.0 50.1 38.0 37.1 71.8 83.6 96.1 123.9 44.5 165.8 27.9 21.1 27.5 29.5 18.6 86.9 115.7 44.7 40.0 107.1 152.4 130.5 191.3 63.5 66.6 23.0 16.5 91.4 73.0 87.1 45.1 34.6 35.2 38.2 407.8 33.7 71.0 49.8 280.5 56.8 58.4 36.5 42.7 74.0 528.7 31.0 51.9 28.4 147.4 60.3 36.5 65.1 128.7 35.2 58.8 14.4 67.9 34.8 335.3 4.6 14.1 7.1 10.2 19.4 9.9 5.4 8.1 9.2 14.5 4.6 10.3 12.9 3.3 11.2 23.4 7.1 9.6 23.4 78.2 77.9 84.1 82.4 77.3 74.9 85.4 80.8 81.2 84.7 80.3 84.8 10.0 9.6 34.6 43.1 8.7 11.9 23.1 20.7 22.2 35.8 31.6 43.6 122.8 11.5 14.6 25.8 37.5 7.1 10.7 185.2 11.7 17.6 3.5 12.7 17.2 13.5 28.2 8.6 22.9 16.5 7.2 15.3 40.2 21.6 6.3 16.2 8.9 5.8 10.8 18.5 26.9 47.3 57.0 13.8 10.7 9.2 27.4 18.5 35.6 15.0 16.6 21.3 15.5 11.6 19.1 27.0 68.5 86.5 22.9 17.6 20.9 11.1 11.9 9.3 0.0 13.5 23.1 2.0 8.5 15.3 10.1 4.4 12.9 20.3 72.0 9.7 QARS1 QARS ENSG00000172053 "Glutaminyl-tRNA synthetase 1" P47897 3 49095932-49105130 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Epilepsy, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Cardiomyocytes: 55.5;Cytotrophoblasts: 193.9;Extravillous trophoblasts: 156.7;Hofbauer cells: 96.1;Syncytiotrophoblasts: 187.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036986, HPA036987" Enhanced Enhanced Cytosol No No 58000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA036986: AB_10672344, HPA036987: AB_2675418" "prognostic favorable (1.43e-4)" "unprognostic (1.96e-1)" "unprognostic (7.31e-2)" "unprognostic (1.10e-2)" "unprognostic (5.13e-3)" "unprognostic (6.62e-3)" "unprognostic (6.53e-3)" "unprognostic (1.52e-2)" "unprognostic (1.17e-1)" "unprognostic (2.51e-1)" "unprognostic (4.33e-1)" "unprognostic (9.14e-2)" "prognostic favorable (5.60e-6)" "unprognostic (2.73e-3)" "unprognostic (1.65e-1)" "unprognostic (2.74e-2)" "unprognostic (3.11e-1)" 61.1 58.8 20.0 57.2 21.3 96.6 89.5 23.5 18.5 58.3 34.2 104.8 101.6 45.5 58.5 102.5 71.0 48.3 72.0 18.4 21.1 57.1 51.1 52.3 75.8 23.8 21.0 69.0 73.9 78.1 33.0 76.7 23.0 60.4 121.0 21.4 103.2 61.1 156.1 105.0 84.6 60.2 22.7 60.1 75.0 30.0 23.0 92.3 53.2 146.2 118.8 72.8 58.1 24.6 95.9 97.8 128.0 197.4 146.4 180.8 159.2 90.5 188.2 160.5 152.9 123.0 113.5 257.1 61.4 136.7 95.3 119.9 166.3 137.8 111.4 78.2 148.0 206.4 156.0 216.1 91.2 187.2 130.9 184.8 123.1 127.4 108.1 175.3 184.7 144.6 95.3 112.4 118.0 89.2 130.7 154.9 116.1 159.0 122.9 76.0 123.7 200.6 108.5 163.9 48.7 161.6 85.4 211.0 147.8 122.7 184.4 205.5 137.6 82.8 127.3 131.7 117.9 111.9 176.5 142.9 88.4 156.3 60.3 30.7 84.3 25.8 44.5 104.1 57.4 62.2 54.1 47.0 127.0 49.9 46.6 49.0 8.0 71.8 94.5 57.4 82.1 81.2 20.0 21.3 23.5 18.5 18.4 21.1 23.8 21.0 23.0 22.7 23.0 24.6 15.1 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.5 0.0 0.0 0.0 0.0 193.9 11.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 156.7 14.7 0.0 0.0 0.0 0.0 0.0 0.0 96.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 187.0 2.0 0.0 0.0 0.0 QPCT "GCT, QC" ENSG00000115828 "Glutaminyl-peptide cyclotransferase" Q16769 2 37342827-37373322 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 170.3;epididymis: 104.0" "Group enriched" "Detected in many" 4 "Enteroendocrine cells: 217.0;Ionocytes: 138.4;Langerhans cells: 163.4;Melanocytes: 528.3" "Cancer enhanced" "Detected in all" "melanoma: 97.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 1527.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 1527.7" "Cell line enhanced" "Detected in many" "SCLC-21H: 117.1;SK-MEL-30: 426.8;U-266/84: 341.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008406 Enhanced Approved Cytosol "Secreted to blood" NA NA 390000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA008406: AB_1855981" "unprognostic (6.25e-3)" "unprognostic (6.69e-2)" "unprognostic (4.95e-2)" "unprognostic (1.44e-1)" "unprognostic (1.44e-2)" "unprognostic (9.32e-2)" "unprognostic (1.13e-3)" "unprognostic (9.73e-2)" "unprognostic (2.71e-3)" "unprognostic (7.86e-2)" "unprognostic (3.67e-2)" "unprognostic (1.17e-1)" "unprognostic (6.78e-2)" "unprognostic (7.76e-3)" "unprognostic (1.21e-1)" "unprognostic (9.48e-3)" "unprognostic (3.62e-3)" 5.6 170.3 8.4 14.2 7.5 47.3 15.8 5.1 11.5 21.2 4.2 25.3 5.6 9.8 104.0 3.4 2.2 10.8 5.1 8.9 27.4 6.1 2.6 5.6 8.1 9.7 11.6 1.0 13.7 14.8 27.0 9.2 14.7 7.2 10.2 11.9 25.5 6.7 4.1 36.3 4.5 8.3 7.8 13.9 7.6 2.0 20.3 5.1 3.8 2.8 12.5 15.2 4.6 6.7 1.0 40.7 0.1 0.0 6.0 13.3 0.1 6.6 86.5 6.4 10.1 2.9 7.1 0.2 3.0 32.6 72.9 0.1 2.7 0.6 10.3 0.6 76.0 18.7 0.3 7.7 0.6 3.0 0.1 8.5 0.0 47.3 0.2 0.4 26.2 0.0 0.0 0.0 0.2 4.5 0.0 1.7 0.6 0.3 0.0 0.0 0.0 0.8 42.6 10.9 117.1 0.2 6.4 1.4 426.8 8.0 0.7 2.9 19.4 0.0 0.2 0.1 0.6 15.3 341.7 0.3 25.8 0.3 0.0 9.8 344.8 3.2 0.4 38.7 1.0 2.6 0.6 0.5 124.7 1.2 0.5 0.3 1527.7 0.2 3.3 2.4 0.1 169.8 8.4 7.5 5.1 11.5 8.9 27.4 9.7 11.6 14.7 7.8 20.3 6.7 1.8 3.2 2.3 0.3 12.5 39.0 13.6 40.0 2.2 21.8 7.9 8.5 1.1 1.5 17.7 22.0 2.1 0.7 0.8 6.1 1.9 45.4 0.6 2.6 24.7 17.5 217.0 1.7 8.5 2.4 6.1 26.7 3.1 4.0 55.3 1.6 22.5 0.3 20.5 43.7 7.3 6.6 138.4 21.2 163.4 2.9 3.1 26.8 528.3 6.5 64.3 0.8 3.1 3.0 1.3 31.8 1.8 23.7 26.0 9.1 0.2 11.7 4.3 3.2 13.1 0.6 6.6 1.7 0.7 0.6 14.5 4.7 5.6 5.0 7.3 5.8 RAB32 ENSG00000118508 "RAB32, member RAS oncogene family" Q13637 6 146543833-146554953 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 175.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 232.6;Kupffer cells: 254.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 86.5" "Group enriched" "Detected in many" 42 "dendritic cells: 42.5;granulocytes: 86.5;monocytes: 46.8" "Low cell line specificity" "Detected in many" HPA025731 Approved Approved Cytosol NA NA 63000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA025731: AB_1856001" "unprognostic (3.07e-1)" "unprognostic (5.32e-2)" "prognostic favorable (1.56e-4)" "prognostic unfavorable (6.51e-4)" "unprognostic (1.26e-1)" "unprognostic (2.34e-3)" "prognostic unfavorable (1.08e-7)" "unprognostic (2.64e-2)" "unprognostic (9.71e-2)" "unprognostic (3.38e-2)" "unprognostic (2.80e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (8.62e-4)" "unprognostic (1.54e-1)" "unprognostic (6.31e-2)" "unprognostic (1.73e-1)" "unprognostic (2.67e-1)" 35.0 16.5 7.5 29.7 7.8 175.1 27.0 8.6 11.0 19.0 9.2 38.3 17.4 26.5 14.6 11.6 20.8 24.1 17.9 7.1 8.2 21.3 50.2 32.1 22.3 9.9 8.2 13.0 12.2 8.3 5.0 14.8 8.9 14.5 37.7 2.2 18.1 16.9 4.6 20.2 18.4 46.5 9.2 54.1 19.4 33.3 8.8 22.5 11.0 8.3 15.2 28.6 15.4 11.7 65.5 34.5 38.7 65.3 58.0 98.5 0.1 123.3 138.4 167.7 276.7 21.2 31.6 0.1 43.9 132.2 183.5 84.2 2.4 80.4 225.2 0.4 29.1 82.4 78.3 77.3 252.1 114.2 115.9 87.6 133.1 95.8 135.3 86.7 110.5 0.0 15.8 0.4 92.8 15.8 52.0 61.8 5.0 0.0 65.2 0.0 41.5 0.9 65.6 45.2 0.1 50.6 144.7 17.6 219.3 34.3 33.7 91.7 88.0 50.2 67.7 133.1 152.6 0.2 9.4 0.4 115.1 86.0 69.3 86.5 46.8 8.2 0.0 21.2 0.0 0.0 0.0 0.1 42.5 0.0 0.1 0.0 16.5 1.3 15.4 2.2 0.0 14.4 7.5 7.8 8.6 11.0 7.1 8.2 9.9 8.2 8.9 9.2 8.8 11.7 30.8 48.1 9.4 2.9 4.1 53.5 95.3 92.6 17.6 1.4 29.0 38.9 2.0 52.9 36.8 11.0 4.2 2.2 3.4 64.1 25.4 164.4 96.9 8.5 40.3 34.3 60.1 14.9 2.3 105.7 6.9 51.5 18.3 12.4 57.8 27.7 27.5 75.4 232.6 0.0 1.3 31.3 22.4 254.6 101.7 156.7 24.5 146.7 168.9 24.4 147.2 9.0 2.1 4.0 4.6 154.3 46.3 25.6 0.5 99.6 33.3 83.2 9.5 1.4 19.7 46.1 46.3 70.9 14.2 2.5 19.0 3.1 7.0 33.1 62.5 65.6 RAB3C ENSG00000152932 "RAB3C, member RAS oncogene family" Q96E17 5 58582221-58859394 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 62.5" "Group enriched" "Detected in many" 4 "Excitatory neurons: 140.6;Inhibitory neurons: 509.9;Oligodendrocyte precursor cells: 131.2" "Cancer enhanced" "Detected in some" "glioma: 1.0;pancreatic cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.7;HEL: 2.5;NB-4: 1.6;SCLC-21H: 10.2;SH-SY5Y: 3.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003160, HPA048156" Enhanced Approved Cytosol NA NA "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA003160: AB_1079731, HPA048156: AB_2680291" "unprognostic (1.30e-1)" "unprognostic (3.35e-2)" "unprognostic (9.94e-2)" "unprognostic (2.23e-2)" "unprognostic (4.17e-2)" "unprognostic (1.85e-2)" "unprognostic (8.73e-3)" "unprognostic (3.40e-2)" "unprognostic (6.90e-2)" "unprognostic (7.58e-2)" "unprognostic (9.52e-4)" "unprognostic (1.51e-3)" "unprognostic (3.70e-5)" "unprognostic (4.70e-2)" "unprognostic (1.05e-1)" "unprognostic (9.65e-2)" "unprognostic (3.61e-3)" 1.1 9.0 19.1 1.2 20.6 0.0 0.7 0.9 32.7 0.1 0.0 0.6 1.6 0.7 0.0 0.2 0.2 0.7 0.1 10.2 62.5 0.0 0.1 0.1 0.2 7.4 12.3 0.3 1.7 0.1 6.8 0.1 31.6 0.0 0.8 6.0 0.1 0.0 0.1 0.0 1.8 0.7 3.9 0.0 0.9 0.1 19.2 0.1 0.1 0.0 0.2 0.6 0.2 3.8 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 1.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 10.2 3.7 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.1 20.6 0.9 32.7 10.2 62.5 7.4 12.3 31.6 3.9 19.2 3.8 8.6 0.0 0.6 10.1 0.4 0.1 0.0 0.0 0.0 28.3 0.3 0.3 0.7 0.0 0.0 0.0 4.2 0.0 0.0 0.0 3.9 0.1 20.0 0.0 0.1 12.1 57.6 1.3 140.6 9.6 0.8 0.2 0.0 0.0 2.5 0.0 5.7 1.2 0.1 3.3 509.9 5.5 0.0 0.9 1.1 11.8 0.9 0.1 1.8 6.5 0.0 1.6 0.0 131.2 8.4 3.9 1.2 0.7 0.0 0.0 0.3 0.1 0.0 6.7 13.1 0.5 0.2 2.4 4.1 0.0 0.1 0.0 1.3 0.1 0.3 0.0 RAB5IF "C20orf24, PNAS-11, RCAF1, RIP5" ENSG00000101084 "RAB5 interacting factor" Q9BUV8 20 36605779-36612557 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 216.9" "Cell type enhanced" "Detected in many" "Ductal cells: 215.9;Exocrine glandular cells: 348.7;Hofbauer cells: 242.6;Pancreatic endocrine cells: 442.2;Proximal tubular cells: 147.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA057387 Uncertain Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA057387: AB_2683425" "unprognostic (2.14e-1)" "unprognostic (4.75e-3)" "unprognostic (6.83e-2)" "unprognostic (1.78e-3)" "unprognostic (3.88e-1)" "unprognostic (2.24e-2)" "prognostic unfavorable (4.56e-6)" "unprognostic (4.47e-3)" "unprognostic (3.89e-1)" "unprognostic (2.90e-1)" "unprognostic (2.37e-2)" "unprognostic (8.60e-2)" "prognostic unfavorable (2.46e-4)" "unprognostic (2.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.00e-1)" "unprognostic (9.98e-2)" 45.2 49.0 33.0 46.4 33.4 69.0 33.4 36.0 40.4 45.4 35.8 71.6 49.3 29.1 40.9 152.2 27.3 38.6 53.0 32.8 34.9 53.1 115.7 41.9 38.6 35.0 33.7 22.6 42.8 55.2 20.8 33.4 34.4 29.8 59.9 28.6 56.3 27.6 216.9 39.8 43.2 34.7 35.4 57.0 48.5 37.5 36.1 41.6 27.8 78.2 56.4 50.3 58.1 37.0 224.8 164.4 59.9 75.2 127.2 74.8 142.5 135.8 79.4 132.7 119.5 455.9 279.5 96.6 327.4 122.2 244.8 163.2 123.3 219.3 130.5 73.5 119.1 230.0 233.3 516.7 149.1 247.4 109.3 92.6 225.0 187.7 110.1 70.4 124.5 104.0 158.9 226.4 125.2 156.9 148.6 318.2 98.5 227.1 344.6 114.8 137.2 245.9 119.3 163.5 99.3 76.0 195.3 513.2 187.6 89.3 111.5 206.5 135.1 192.6 132.5 195.3 211.7 138.8 236.0 162.2 204.4 281.3 104.7 22.0 76.9 97.3 17.7 38.9 17.8 35.7 21.2 27.4 47.9 33.6 26.1 19.4 120.6 18.4 46.4 32.8 39.8 28.1 33.0 33.4 36.0 40.4 32.8 34.9 35.0 33.7 34.4 35.4 36.1 37.0 47.5 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 87.1 64.5 0.0 0.0 0.0 42.3 0.0 83.1 111.1 0.0 76.3 215.9 0.0 43.0 34.8 24.4 0.0 0.0 0.0 348.7 126.8 14.5 0.0 61.6 0.0 24.3 0.0 0.0 242.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.0 0.0 0.0 93.0 0.0 0.0 0.0 0.0 442.2 0.0 0.0 11.9 0.0 0.0 147.8 0.0 0.0 0.0 0.0 33.6 0.0 0.0 0.0 0.0 135.6 27.0 29.9 0.0 0.0 RABGAP1 "GAPCenA, TBC1D11" ENSG00000011454 "RAB GTPase activating protein 1" Q9Y3P9 9 122940833-123104866 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 179.1;Oligodendrocytes: 147.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064860, HPA072273" Enhanced Enhanced Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA064860: AB_2685372, HPA072273: AB_2686504" "prognostic unfavorable (8.09e-4)" "unprognostic (3.45e-1)" "unprognostic (3.85e-3)" "unprognostic (3.90e-1)" "unprognostic (4.16e-2)" "unprognostic (1.16e-1)" "unprognostic (1.53e-1)" "unprognostic (3.75e-2)" "unprognostic (5.19e-2)" "unprognostic (3.52e-2)" "unprognostic (1.88e-2)" "unprognostic (2.76e-1)" "prognostic favorable (6.06e-6)" "unprognostic (1.39e-1)" "unprognostic (2.75e-1)" "unprognostic (8.72e-2)" "unprognostic (3.05e-2)" 22.5 15.5 27.3 16.9 28.8 7.3 21.6 23.8 31.6 21.9 19.4 39.7 12.2 28.8 25.4 31.7 21.9 19.0 26.3 28.0 27.8 19.9 11.7 19.3 19.5 27.3 29.8 23.8 16.3 31.3 16.8 21.4 28.0 29.4 22.7 24.9 24.3 30.2 34.5 23.6 17.2 31.7 26.1 18.4 21.6 21.8 27.1 19.6 39.2 30.7 19.4 26.0 21.8 30.2 19.5 25.7 39.6 33.0 44.8 36.2 24.5 20.0 35.8 30.3 28.2 29.9 18.6 26.6 15.6 31.3 40.4 64.7 25.6 25.0 32.4 25.1 15.4 20.8 40.4 22.9 38.3 17.2 17.5 35.2 37.6 26.1 29.3 43.5 34.8 26.2 18.3 19.9 36.9 43.3 22.5 13.5 14.6 55.7 19.6 36.7 72.3 23.0 25.2 21.3 22.3 17.2 35.7 31.9 18.6 29.5 60.7 9.4 26.9 25.6 15.1 28.3 20.3 19.3 33.9 27.7 24.0 8.7 22.9 3.4 1.3 1.8 0.9 2.1 0.7 1.1 0.9 0.9 1.1 1.4 1.6 1.1 2.1 0.8 1.0 1.5 1.2 0.5 27.3 28.8 23.8 31.6 28.0 27.8 27.3 29.8 28.0 26.1 27.1 30.2 47.2 25.6 50.8 115.2 26.6 18.0 23.0 20.8 40.5 44.9 26.7 26.4 46.9 11.5 31.9 11.0 50.1 25.5 26.0 24.9 3.9 11.8 15.4 31.5 30.3 33.1 16.9 17.0 179.1 14.5 8.7 22.9 18.3 47.7 14.0 34.2 27.1 15.4 15.9 57.2 129.7 16.7 24.4 28.6 14.4 17.5 40.7 25.1 14.2 78.7 35.9 33.6 33.0 101.0 147.7 13.0 18.6 51.6 11.9 39.7 11.7 10.1 30.6 34.6 85.5 31.0 51.4 73.8 37.4 27.6 17.3 41.6 16.4 22.5 21.6 27.8 RANBP1 HTF9A ENSG00000099901 "RAN binding protein 1" P43487 22 20115938-20127355 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 754.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 2431.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065868, HPA065931" Supported Enhanced Cytosol NA NA 1400000 "Cluster 26: Non-specific - Mitochondria" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA065868: AB_2685572, HPA065931: AB_2685580" "unprognostic (1.25e-1)" "unprognostic (1.08e-1)" "unprognostic (4.43e-3)" "unprognostic (6.55e-3)" "unprognostic (4.35e-2)" "unprognostic (2.50e-2)" "prognostic unfavorable (1.58e-6)" "unprognostic (2.83e-2)" "unprognostic (2.21e-2)" "unprognostic (5.67e-3)" "unprognostic (1.54e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.16e-6)" "unprognostic (2.40e-2)" "unprognostic (3.95e-1)" "unprognostic (4.44e-2)" "unprognostic (7.30e-2)" 65.5 68.0 37.6 63.3 38.6 117.5 60.7 40.2 47.9 67.1 28.8 63.9 52.9 66.7 21.4 94.7 61.2 30.0 47.5 39.7 40.5 64.8 86.7 53.5 94.7 41.1 39.1 61.0 54.0 35.9 50.3 46.2 41.4 49.8 42.9 35.3 51.8 34.3 54.9 61.8 60.6 36.2 40.8 71.1 55.5 117.8 39.6 104.0 46.5 34.8 72.6 61.9 64.7 43.7 434.6 218.5 479.7 263.2 79.1 93.8 403.7 388.7 169.3 494.6 356.4 401.5 150.8 669.8 169.7 157.8 224.9 394.2 449.4 340.4 269.6 290.1 1071.3 562.6 218.5 426.6 120.3 913.7 294.4 103.9 158.7 393.0 139.2 114.3 227.1 300.2 2431.9 261.1 226.8 339.2 665.5 622.0 547.2 553.8 380.8 667.4 674.7 172.6 171.6 233.9 478.6 354.7 356.6 196.4 236.6 210.3 137.1 378.9 176.4 341.5 668.1 258.7 438.3 260.9 383.6 1066.0 186.9 405.9 292.7 21.1 94.7 75.8 71.3 101.6 78.8 123.1 101.6 91.1 111.5 119.1 101.8 77.0 9.5 90.8 93.6 103.6 115.4 102.5 37.6 38.6 40.2 47.9 39.7 40.5 41.1 39.1 41.4 40.8 39.6 43.7 133.1 35.3 37.1 14.7 135.0 274.4 195.0 260.6 109.3 44.4 142.3 175.6 47.1 104.4 104.8 90.1 6.2 409.2 103.8 106.4 277.8 188.5 394.2 104.6 131.1 143.5 117.6 259.2 22.2 112.3 754.9 156.7 72.4 86.7 64.7 187.2 93.5 169.5 268.7 37.0 21.4 194.0 209.5 85.5 223.3 236.1 145.1 95.3 177.9 6.5 140.6 103.5 87.6 7.5 23.9 150.0 109.3 136.9 179.6 338.0 107.3 213.7 93.8 39.0 98.6 110.9 289.5 505.1 435.2 220.1 294.9 194.7 119.2 176.5 273.6 218.2 RAP1GAP "KIAA0474, RAP1GA1, RAP1GAP1, RAP1GAPII" ENSG00000076864 "RAP1 GTPase activating protein" P47736 1 21596215-21669363 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 152.4;thyroid gland: 162.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 64.1;Distal tubular cells: 72.4;Excitatory neurons: 82.0;Horizontal cells: 92.5;Intestinal goblet cells: 112.6;Oligodendrocyte precursor cells: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 46.3;OE19: 162.8;SCLC-21H: 52.1" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "basal ganglia: 231.1" "HPA001922, CAB003851" Enhanced Supported Approved Cytosol NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol "CAB003851: AB_562338, HPA001922: AB_1079743" "unprognostic (1.17e-2)" "unprognostic (4.33e-2)" "unprognostic (7.84e-2)" "unprognostic (2.45e-2)" "unprognostic (4.52e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (5.85e-4)" "unprognostic (8.33e-2)" "unprognostic (1.52e-2)" "unprognostic (2.35e-1)" "unprognostic (3.43e-2)" "unprognostic (1.35e-2)" "prognostic favorable (1.12e-6)" "unprognostic (1.11e-1)" "unprognostic (9.85e-3)" "unprognostic (4.86e-3)" "unprognostic (3.64e-2)" 0.6 80.8 74.0 2.6 118.6 0.8 4.4 24.6 91.9 7.5 0.0 19.7 12.4 1.9 1.9 7.5 4.2 24.9 9.5 76.2 34.5 152.4 36.1 14.2 1.0 35.8 22.0 1.6 106.2 57.1 37.9 2.1 32.8 12.8 17.3 27.3 88.7 0.8 0.2 3.5 21.7 0.7 15.8 1.2 110.8 3.6 32.4 0.5 162.8 0.3 0.9 4.0 3.4 67.3 6.2 46.3 0.5 3.6 0.0 0.0 0.8 0.0 0.1 0.1 0.0 4.3 6.4 0.1 4.6 0.2 30.2 7.9 4.4 0.3 0.1 1.0 2.3 2.2 4.3 22.1 0.7 0.0 6.6 0.3 3.1 0.0 0.0 0.0 0.0 22.1 29.6 1.1 0.0 15.6 7.7 0.7 2.8 162.8 7.0 4.3 1.2 1.1 10.2 3.4 52.1 9.3 7.7 27.4 8.9 1.8 2.7 5.2 0.1 0.0 3.1 0.0 0.1 0.6 0.1 0.0 0.1 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.0 118.6 24.6 91.9 76.2 34.5 35.8 22.0 32.8 15.8 32.4 67.3 0.0 9.6 29.3 10.4 0.5 1.3 1.1 1.1 0.6 64.1 8.5 5.6 5.1 25.8 4.5 14.7 0.0 0.2 0.1 4.3 72.4 25.1 0.8 3.1 0.6 0.4 6.7 4.0 82.0 28.8 1.4 1.0 17.3 8.0 0.0 6.2 0.4 8.5 0.3 92.5 45.8 112.6 6.1 0.6 0.3 0.3 0.0 0.6 16.0 3.7 0.6 11.5 0.0 51.8 18.6 15.3 17.2 0.0 0.2 5.0 6.0 13.5 1.2 7.3 0.0 0.0 0.7 1.0 3.6 0.5 1.1 1.5 0.3 2.5 7.7 2.6 RAP1GDS1 SmgGDS ENSG00000138698 "Rap1 GTPase-GDP dissociation stimulator 1" P52306 4 98261384-98443858 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "GTPase activation" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 72.4" "Cell type enhanced" "Detected in many" "Early spermatids: 434.9;Inhibitory neurons: 176.3;Late spermatids: 245.3;Oligodendrocytes: 357.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019060 Approved Supported Cytosol NA NA 62000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA019060: AB_1856068" "unprognostic (8.12e-2)" "unprognostic (1.50e-1)" "unprognostic (2.69e-3)" "unprognostic (1.66e-1)" "unprognostic (9.11e-2)" "unprognostic (1.35e-2)" "unprognostic (1.57e-3)" "unprognostic (3.44e-1)" "unprognostic (6.31e-2)" "unprognostic (1.27e-1)" "unprognostic (3.15e-1)" "unprognostic (4.60e-1)" "prognostic favorable (2.00e-4)" "unprognostic (7.11e-2)" "unprognostic (3.09e-1)" "unprognostic (1.47e-1)" "unprognostic (2.76e-1)" 15.6 12.6 49.3 18.8 54.9 14.3 17.4 56.3 56.7 11.7 25.2 16.5 10.0 12.2 11.2 18.5 9.6 11.6 9.6 48.3 54.1 16.5 21.1 14.0 23.4 59.5 62.6 10.8 19.1 10.3 16.1 13.2 67.6 10.3 18.6 65.7 12.5 15.1 5.8 14.4 14.3 22.1 51.9 18.0 11.2 22.6 64.4 32.4 17.6 5.7 24.4 19.0 12.9 72.4 50.8 30.4 37.8 32.8 47.6 56.4 14.2 86.7 48.6 51.1 40.0 22.7 66.5 61.0 26.3 65.9 24.3 27.8 47.0 80.5 68.7 60.4 17.1 37.0 35.6 29.6 93.8 64.1 25.2 65.7 47.8 45.3 69.5 42.3 67.9 61.9 25.7 51.6 128.3 27.7 104.9 31.3 13.9 43.0 19.0 41.5 22.4 20.8 51.7 40.8 55.0 32.5 36.2 81.2 48.9 20.6 18.5 41.5 67.2 52.7 36.8 23.9 51.7 16.5 30.1 51.1 43.9 47.3 69.7 32.8 17.4 10.4 23.3 24.9 24.2 23.9 24.4 23.5 27.9 17.1 12.3 19.5 2.5 37.0 28.5 60.6 41.2 14.8 49.3 54.9 56.3 56.7 48.3 54.1 59.5 62.6 67.6 51.9 64.4 72.4 17.6 16.0 12.2 88.8 34.7 13.9 10.8 11.7 22.8 48.2 17.1 12.2 11.1 14.3 14.7 16.5 50.1 6.8 45.7 9.7 23.5 17.7 434.9 7.4 16.2 15.7 20.9 19.8 146.4 20.9 16.5 11.5 16.8 11.2 15.2 19.8 13.9 18.5 23.8 15.2 176.3 13.0 12.2 33.4 27.6 245.3 9.3 24.7 17.8 89.0 32.6 16.9 34.0 110.6 357.6 23.4 14.6 10.9 30.4 16.3 14.5 20.4 7.6 77.5 0.0 12.7 17.2 16.7 36.5 26.8 16.8 4.5 34.3 19.8 18.4 15.1 RBM46 "CT68, MGC27016" ENSG00000151962 "RNA binding motif protein 46" Q8TBY0 4 154781213-154828813 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 55 "testis: 27.6" "Group enriched" "Detected in some" 5 "Spermatocytes: 135.7;Spermatogonia: 82.1" "Cancer enriched" "Detected in single" 15 "testis cancer: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SuSa: 1.4" "Low region specificity" "Detected in single" "Region enriched" "Detected in many" 8 "spinal cord: 12.9" HPA037746 Approved Cytosol NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 5: NTERA-2 - Transcription" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Cytosol "HPA037746: " "unprognostic (4.79e-1)" "unprognostic (1.14e-2)" "unprognostic (3.23e-1)" "unprognostic (1.59e-2)" "unprognostic (3.33e-3)" "unprognostic (1.13e-1)" "unprognostic (8.11e-2)" "unprognostic (2.24e-2)" "unprognostic (2.99e-7)" "unprognostic (4.86e-2)" "unprognostic (7.31e-2)" "unprognostic (4.27e-2)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 27.6 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.6 0.6 0.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 0.3 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.3 0.0 4.3 0.4 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 9.7 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.6 135.7 82.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RBMS1 "C2orf12, DKFZp564H0764, HCC-4, MSSP-1, MSSP-2, MSSP-3, SCR2, YC1" ENSG00000153250 "RNA binding motif single stranded interacting protein 1" P29558 2 160272151-160493807 "Predicted intracellular proteins" "DNA replication" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 398.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047943, HPA061791" Enhanced Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA047943: AB_2797235, HPA061791: AB_2684611" "unprognostic (2.81e-1)" "unprognostic (2.44e-2)" "unprognostic (3.78e-2)" "unprognostic (1.38e-3)" "unprognostic (2.50e-1)" "unprognostic (6.81e-3)" "prognostic unfavorable (4.45e-4)" "unprognostic (6.17e-2)" "unprognostic (4.85e-2)" "unprognostic (1.14e-1)" "unprognostic (7.16e-3)" "unprognostic (6.70e-2)" "prognostic unfavorable (1.33e-7)" "unprognostic (1.84e-3)" "unprognostic (1.50e-1)" "unprognostic (2.36e-1)" "unprognostic (2.32e-1)" 58.2 22.6 8.7 43.3 13.3 35.8 34.5 9.7 11.9 36.6 17.2 38.9 12.8 51.7 12.6 28.9 31.6 34.1 41.0 7.2 10.7 36.5 22.3 47.7 28.3 13.8 12.3 44.1 10.2 50.4 16.0 83.8 15.0 24.0 15.8 6.8 19.2 28.6 16.4 29.4 20.5 56.9 10.9 40.7 20.1 10.4 13.4 26.1 23.0 23.8 22.0 57.0 31.6 10.2 50.5 18.2 63.9 8.4 90.2 155.6 77.1 62.7 89.1 42.4 43.8 50.9 36.9 0.4 76.3 106.6 20.0 30.0 31.1 46.0 69.2 40.9 23.2 18.9 44.2 41.0 82.3 30.8 1.1 187.9 35.6 73.7 32.8 56.7 67.5 15.1 1.2 23.0 103.2 39.4 28.8 31.2 39.3 8.3 40.1 21.6 55.7 25.5 64.9 61.1 8.3 21.7 39.1 22.9 60.2 78.8 11.7 47.9 81.7 75.3 47.7 69.7 57.5 12.2 0.7 21.2 60.7 46.2 49.2 4.0 20.5 26.2 8.6 12.0 29.5 0.9 14.9 13.3 13.7 1.9 24.1 10.9 44.4 13.7 6.9 7.6 2.7 11.0 8.7 13.3 9.7 11.9 7.2 10.7 13.8 12.3 15.0 10.9 13.4 10.2 102.8 112.2 97.8 12.1 37.3 91.1 110.0 59.1 55.2 3.0 44.7 43.2 62.3 18.6 48.1 69.9 0.0 99.1 83.9 0.4 25.4 24.5 59.2 39.8 141.4 126.0 0.0 38.3 132.7 47.3 112.6 161.8 36.7 42.0 20.3 40.8 162.8 29.1 126.3 1.7 136.1 0.5 22.4 123.4 80.2 15.5 88.9 103.8 55.2 153.6 81.2 20.8 93.7 116.1 19.7 96.4 1.3 98.9 23.3 107.0 0.3 36.4 54.1 1.4 78.9 113.6 185.9 6.7 14.5 47.3 82.5 398.3 113.0 53.4 0.5 175.5 RCAN1 DSCR1 ENSG00000159200 "Regulator of calcineurin 1" P53805 21 34513142-34615113 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 256.2;parathyroid gland: 453.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 245.5;Endometrial ciliated cells: 336.9;Glandular and luminal cells: 504.9" "Cancer enhanced" "Detected in all" "glioma: 41.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "SK-MEL-30: 1323.8;WM-115: 815.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037218, HPA068436" Enhanced Approved Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 44: Endometrium - Transcription" Cytosol "CAB037218: AB_2179743, HPA068436: " "unprognostic (3.83e-2)" "unprognostic (4.40e-1)" "unprognostic (1.04e-1)" "unprognostic (7.55e-2)" "unprognostic (9.51e-2)" "unprognostic (1.09e-1)" "unprognostic (2.82e-3)" "unprognostic (5.27e-2)" "unprognostic (7.99e-2)" "unprognostic (4.83e-2)" "unprognostic (2.71e-1)" "unprognostic (2.04e-1)" "unprognostic (4.07e-3)" "unprognostic (1.54e-3)" "unprognostic (1.68e-1)" "unprognostic (2.45e-2)" "unprognostic (2.60e-3)" 58.5 22.0 59.0 50.3 68.2 6.3 65.0 64.6 79.8 86.4 69.9 39.0 31.6 28.7 8.9 24.5 12.4 57.4 61.6 57.5 65.7 89.8 256.2 38.6 12.9 68.1 65.3 8.7 64.1 453.5 30.7 95.6 68.3 24.1 39.5 13.1 20.4 15.1 34.4 29.1 27.6 48.7 67.4 14.6 34.9 10.5 72.7 82.2 61.0 31.8 9.7 101.3 20.9 75.0 47.7 9.5 47.9 29.6 25.7 15.9 29.1 175.8 181.3 71.1 70.5 54.1 44.7 0.8 8.1 103.4 139.5 4.1 34.4 35.6 94.5 26.8 21.2 9.5 16.5 25.8 98.1 15.3 28.9 41.4 31.9 84.4 58.7 17.9 23.8 32.5 18.1 45.7 47.7 23.1 145.4 12.2 27.4 48.0 23.5 53.9 37.5 22.2 22.8 81.1 23.0 10.1 128.4 82.2 1323.8 43.3 111.4 25.4 25.8 237.5 24.7 39.9 43.1 38.9 26.4 8.5 77.4 44.4 815.5 0.0 1.1 5.0 0.7 2.1 1.0 1.1 0.8 0.7 1.6 0.8 0.3 0.7 0.5 0.1 2.4 3.0 1.1 0.5 59.0 68.2 64.6 79.8 57.5 65.7 68.1 65.3 68.3 67.4 72.7 75.0 158.3 96.1 52.4 15.3 8.2 94.6 20.7 20.5 38.1 19.4 245.5 142.4 24.9 21.5 32.7 206.0 27.1 10.9 11.8 204.9 21.5 82.0 48.3 336.9 46.4 175.4 3.6 7.4 28.3 18.9 15.3 60.3 23.4 504.9 8.8 3.9 25.0 187.8 58.9 3.3 54.2 30.7 4.1 19.6 74.0 13.1 7.2 39.8 56.9 15.9 29.5 10.9 3.1 41.7 71.3 26.3 140.5 9.8 6.1 16.3 41.2 142.3 14.1 7.5 0.0 30.3 68.9 10.8 2.6 12.3 79.3 11.1 11.5 10.5 16.3 50.4 REG3A "HIP, PAP, PAP1, PBCGF, REG-III, REG3" ENSG00000172016 "Regenerating family member 3 alpha" Q06141 2 79157003-79159753 "Plasma proteins, Predicted secreted proteins, Transporters" "Acute phase, Inflammatory response" Antimicrobial "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 61 "intestine: 6743.6;pancreas: 12212.2" "Group enriched" "Detected in some" 11 "Exocrine glandular cells: 1988.6;Pancreatic endocrine cells: 5382.1" "Cancer enhanced" "Detected in some" "pancreatic cancer: 710.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 17.6;EFO-21: 15.8;HDLM-2: 15.4;NB-4: 17.7;RPMI-8226: 24.6;SH-SY5Y: 14.6;U-2 OS: 28.5;U-251 MG: 11.0;U-266/84: 15.1" "HPA047894, HPA048334, HPA060705" Supported Approved Cytosol "Secreted to digestive system" NA NA 23000000 "Cluster 25: Pancreas - Digestion" "Cluster 24: NB-4 - Immune response" "Cluster 1: Pancreatic cells - Digestion" Cytosol "HPA047894: AB_2680202, HPA048334: AB_2680363, HPA060705: AB_2684346" "unprognostic (2.43e-2)" "unprognostic (2.12e-1)" "unprognostic (3.62e-2)" "unprognostic (1.42e-1)" 18.5 10.0 0.0 13.3 0.0 0.2 0.6 0.0 0.0 0.3 0.0 19.2 5180.0 2.9 0.0 1.4 0.2 24.9 1.0 0.0 0.0 2.6 2.0 0.5 4.9 0.0 0.0 0.9 12212.2 0.0 2.1 0.1 0.0 0.5 0.0 0.0 2.1 0.0 0.6 0.4 6743.6 0.2 0.0 1.3 156.5 0.9 0.0 0.0 0.6 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 0.1 0.4 0.0 0.0 0.0 24.6 0.0 0.0 1.8 14.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 28.5 5.4 11.0 0.0 15.1 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 152.8 7.7 0.0 0.0 3.0 0.0 0.0 0.0 1988.6 0.0 0.0 189.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 130.2 0.0 0.0 0.0 6.8 0.0 1.4 0.0 0.0 55.8 0.0 0.0 0.0 0.0 5382.1 32.5 0.0 0.2 0.0 215.0 0.0 0.0 0.0 0.0 0.0 16.7 0.0 0.1 0.0 0.0 0.0 0.1 0.0 315.9 0.0 REG3G "LPPM429, PAP1B, UNQ429" ENSG00000143954 "Regenerating family member 3 gamma" Q6UW15 2 79025686-79028505 "Predicted secreted proteins" "Acute phase, Inflammatory response" Antimicrobial "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "pancreas: 3517.1" "Cell type enhanced" "Detected in some" "Exocrine glandular cells: 184.9;Pancreatic endocrine cells: 53.5;Proximal enterocytes: 39.4" "Cancer enriched" "Detected in many" 13 "pancreatic cancer: 71.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047894, HPA048334, HPA060705" Uncertain Approved Cytosol "Secreted to digestive system" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 1: Pancreatic cells - Digestion" Cytosol "HPA047894: AB_2680202, HPA048334: AB_2680363, HPA060705: AB_2684346" "unprognostic (3.29e-1)" "unprognostic (2.20e-1)" "unprognostic (1.29e-1)" "unprognostic (8.82e-2)" "unprognostic (7.20e-3)" "unprognostic (5.64e-2)" 1.0 46.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.3 2.4 0.1 165.7 0.3 0.3 0.0 0.2 0.0 0.0 6.0 0.4 0.1 0.0 0.0 0.0 0.2 3517.1 0.0 0.3 1.1 0.0 0.1 0.0 0.0 0.3 1.3 0.2 0.1 37.0 1.5 0.0 0.2 0.4 57.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.7 0.0 0.0 0.1 0.0 0.0 0.0 184.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 6.2 0.6 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 53.5 0.0 0.7 0.0 0.4 39.4 2.2 0.0 0.0 0.0 0.0 0.2 1.3 1.2 0.0 0.0 0.0 0.0 0.9 5.4 0.0 RELA "NFKB3, p65" ENSG00000173039 "RELA proto-oncogene, NF-kB subunit" Q04206 11 65653597-65663090 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004264, CAB005030, HPA063461" Supported Enhanced Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 89: Fibroblasts - ECM organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB004264: AB_628017, CAB005030: AB_562171, HPA063461: AB_2685016" "unprognostic (9.17e-2)" "unprognostic (1.79e-1)" "unprognostic (2.04e-1)" "unprognostic (3.22e-1)" "unprognostic (7.67e-2)" "unprognostic (5.39e-2)" "prognostic unfavorable (9.18e-4)" "unprognostic (1.30e-3)" "unprognostic (1.69e-2)" "unprognostic (1.33e-1)" "unprognostic (6.03e-2)" "unprognostic (2.37e-1)" "prognostic unfavorable (5.66e-4)" "unprognostic (2.78e-1)" "unprognostic (1.46e-1)" "unprognostic (9.81e-2)" "unprognostic (2.53e-1)" 67.3 42.8 27.4 38.5 29.9 79.7 63.1 28.7 35.0 61.7 26.9 63.3 31.3 61.0 23.0 60.8 62.3 34.7 49.4 27.3 29.6 50.0 66.6 70.3 39.7 35.5 30.0 65.3 49.0 25.9 32.3 27.8 31.8 55.6 23.8 9.8 54.4 35.4 74.9 66.1 49.1 39.8 29.1 59.7 56.8 24.1 31.4 30.3 45.0 26.9 36.7 60.3 59.4 33.4 66.9 68.4 31.4 45.2 49.1 49.6 32.2 52.9 65.6 62.3 49.9 33.0 71.1 53.0 85.5 75.4 72.0 63.9 36.8 66.6 35.5 62.1 53.2 57.5 50.1 47.5 56.7 43.8 78.8 55.4 65.3 70.4 79.2 58.9 76.6 43.7 56.6 61.4 48.5 90.3 74.1 38.5 20.9 43.6 64.6 61.5 29.6 80.6 50.7 60.9 26.6 59.5 47.1 72.7 72.4 22.2 82.3 29.4 100.3 65.8 55.3 103.3 50.9 86.0 80.5 53.6 71.7 30.8 65.4 12.5 14.0 18.6 22.7 17.1 25.5 17.3 19.8 22.4 15.4 14.0 18.4 20.0 21.2 25.2 15.4 15.3 21.4 16.5 27.4 29.9 28.7 35.0 27.3 29.6 35.5 30.0 31.8 29.1 31.4 33.4 43.2 32.1 25.5 9.1 33.9 47.3 54.4 41.3 33.0 9.4 31.6 27.9 23.1 17.2 30.9 11.0 8.4 24.0 40.7 30.9 29.4 41.4 5.1 32.8 25.7 43.9 19.7 19.0 5.5 45.1 24.8 30.1 33.1 50.0 44.3 26.2 32.9 20.3 24.3 15.2 5.9 25.0 32.6 24.9 40.4 7.7 28.9 28.0 32.0 10.3 35.2 14.5 28.8 7.5 13.8 65.4 20.8 26.4 30.7 66.8 22.2 17.4 23.4 9.5 13.1 30.5 34.7 14.3 20.3 29.2 43.2 43.6 37.9 21.0 21.6 75.1 RETREG2 "C2orf17, FAM134A, MAG-2, MGC3035" ENSG00000144567 "Reticulophagy regulator family member 2" Q8NC44 2 219176225-219185475 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 42.1;Collecting duct cells: 46.0;Ductal cells: 43.8;Exocrine glandular cells: 48.3;Pancreatic endocrine cells: 40.4;Proximal tubular cells: 42.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011170, HPA011844, HPA075910" Approved Approved Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 43: Testis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA011170: AB_1845713, HPA011844: AB_2668544, HPA075910: " "unprognostic (2.63e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (7.95e-4)" "unprognostic (1.03e-1)" "unprognostic (2.88e-2)" "unprognostic (2.58e-3)" "prognostic unfavorable (1.49e-4)" "unprognostic (8.74e-2)" "unprognostic (9.61e-2)" "unprognostic (1.34e-2)" "unprognostic (4.37e-2)" "unprognostic (2.36e-1)" "unprognostic (4.29e-3)" "unprognostic (4.45e-2)" "unprognostic (4.47e-2)" "unprognostic (1.53e-2)" "unprognostic (3.70e-2)" 34.4 47.6 73.6 26.5 74.1 47.4 34.1 73.2 90.1 42.7 66.1 41.3 31.7 35.1 45.9 38.5 38.4 32.1 24.6 74.9 76.6 51.8 57.2 29.7 34.3 77.4 77.3 51.9 52.4 76.6 43.7 28.3 77.2 36.9 38.5 50.6 39.8 29.7 24.9 45.0 36.7 33.9 76.5 38.2 42.9 104.0 78.8 34.3 44.6 27.7 34.6 37.7 35.9 78.0 34.6 36.2 30.5 46.5 113.2 47.7 32.5 41.4 71.3 49.4 42.7 36.3 58.1 28.1 40.4 78.5 101.4 43.3 37.1 37.1 54.1 39.5 31.0 37.5 51.2 61.1 64.7 41.1 49.6 52.0 95.5 55.5 53.3 84.7 45.2 29.9 26.3 62.8 69.3 50.9 24.8 44.4 22.6 44.0 41.5 31.4 33.8 22.7 41.1 40.3 43.6 44.9 26.7 50.8 98.4 47.4 42.4 44.9 36.0 55.0 29.4 78.6 31.5 63.4 39.3 31.5 57.5 40.3 31.0 12.5 6.3 6.3 9.3 8.3 8.3 8.3 7.4 9.5 4.3 5.7 6.6 8.8 23.5 5.2 8.1 6.6 9.6 3.6 73.6 74.1 73.2 90.1 74.9 76.6 77.4 77.3 77.2 76.5 78.8 78.0 22.4 16.0 13.7 0.0 7.9 0.0 0.0 0.0 0.0 0.0 42.1 32.0 0.0 0.0 6.2 46.0 0.0 31.1 21.1 0.0 21.5 43.8 0.0 21.4 19.3 8.6 0.0 0.0 0.0 48.3 37.2 11.9 0.0 30.5 5.1 29.2 0.0 0.0 36.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 11.4 0.0 0.0 0.0 0.0 40.4 0.0 0.0 5.7 0.0 0.0 42.3 2.2 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 30.1 8.2 24.2 0.0 0.0 REV1 REV1L ENSG00000135945 "REV1 DNA directed polymerase" Q9UBZ9 2 99400475-99490035 "Predicted intracellular proteins" "DNA damage, DNA repair, DNA synthesis" "DNA-binding, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044534, HPA051036" Uncertain Approved Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Cytosol "HPA044534: AB_2678975, HPA051036: AB_2681319" "unprognostic (3.05e-1)" "unprognostic (3.15e-2)" "unprognostic (1.09e-1)" "unprognostic (1.94e-1)" "unprognostic (2.15e-1)" "unprognostic (7.87e-3)" "unprognostic (1.30e-3)" "unprognostic (3.56e-3)" "unprognostic (2.78e-3)" "unprognostic (1.01e-1)" "unprognostic (7.33e-2)" "prognostic unfavorable (2.03e-4)" "unprognostic (3.17e-1)" "unprognostic (1.45e-1)" "unprognostic (4.36e-1)" "unprognostic (1.31e-1)" "unprognostic (1.08e-3)" 9.8 11.6 7.0 6.1 7.6 7.0 11.2 13.1 9.6 11.9 9.4 9.3 6.1 14.2 17.3 10.5 11.4 7.9 12.4 7.2 8.7 9.0 10.0 11.2 10.0 7.0 7.4 12.1 6.9 8.8 10.4 7.3 6.8 11.2 9.2 12.2 9.4 12.0 15.7 10.3 9.0 10.1 6.9 9.4 8.2 9.6 8.5 9.7 10.3 23.7 10.0 10.5 11.5 8.5 7.9 2.0 12.4 4.7 9.5 9.3 13.0 8.6 10.8 9.9 11.3 4.6 7.5 15.9 6.7 9.2 10.4 10.9 9.3 11.5 15.3 7.0 5.8 8.1 7.7 10.5 10.6 10.6 16.5 9.1 13.7 8.9 13.0 11.1 12.9 8.1 9.4 5.3 11.1 5.2 11.2 19.0 8.9 5.1 5.2 17.4 8.8 7.0 12.3 13.4 8.0 8.5 7.6 6.4 11.2 13.3 6.6 15.2 9.1 11.7 9.7 4.9 5.7 7.2 7.8 12.8 4.8 13.4 9.2 0.0 0.2 0.0 0.3 0.2 0.2 0.1 0.5 0.4 0.3 0.4 0.9 0.7 0.1 0.3 0.1 0.1 0.3 0.1 7.0 7.6 13.1 9.6 7.2 8.7 7.0 7.4 6.8 6.9 8.5 8.5 45.3 70.5 61.9 59.4 27.7 48.3 57.5 37.8 58.6 84.2 21.7 20.4 52.5 20.0 38.6 22.0 39.6 32.9 17.5 24.1 5.9 18.4 29.2 41.6 32.8 31.6 17.5 35.7 71.3 18.1 20.0 33.8 31.6 30.0 25.3 32.4 23.6 18.0 19.1 82.4 78.2 16.3 26.4 17.6 28.3 21.6 27.1 20.6 19.6 53.4 27.3 36.7 14.4 60.3 77.0 16.4 25.6 46.3 23.3 51.0 30.0 12.5 33.7 57.2 26.3 51.2 28.8 52.1 53.8 36.3 35.5 35.2 26.8 39.7 19.3 63.5 RGN "RC, SMP30" ENSG00000130988 Regucalcin Q15493 X 47078355-47093314 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 184.7;liver: 383.7" "Cell type enhanced" "Detected in many" "Distal tubular cells: 58.7;Granulosa cells: 67.8;Hepatocytes: 175.7;Muller glia cells: 54.5;Peritubular cells: 69.6;Proximal tubular cells: 174.4" "Cancer enriched" "Detected in many" 6 "liver cancer: 47.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 21.7;fHDF/TERT166: 6.9;Hep G2: 32.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA029102, HPA029103, HPA029104" Enhanced Approved Cytosol NA NA 280000 "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA029102: AB_10599846, HPA029103: AB_10602097, HPA029104: " "unprognostic (1.80e-1)" "unprognostic (1.25e-1)" "unprognostic (1.39e-1)" "unprognostic (5.56e-3)" "unprognostic (8.22e-3)" "unprognostic (1.32e-2)" "prognostic favorable (7.55e-4)" "unprognostic (2.60e-3)" "unprognostic (2.23e-2)" "unprognostic (8.38e-2)" "unprognostic (3.37e-2)" "unprognostic (1.14e-2)" "prognostic favorable (5.10e-10)" "unprognostic (1.69e-2)" "unprognostic (2.43e-1)" "unprognostic (7.82e-2)" "unprognostic (5.22e-2)" 7.8 184.7 19.2 0.7 20.8 0.0 3.4 23.0 19.9 12.2 25.9 8.4 13.2 7.2 4.5 3.2 5.4 5.0 13.9 19.0 20.2 56.7 383.7 18.9 1.0 21.6 19.8 21.4 34.0 5.8 8.8 12.1 20.7 13.4 2.1 8.0 14.4 17.3 11.8 1.5 13.6 4.4 21.3 3.7 11.9 3.5 19.3 0.5 18.9 11.3 0.5 7.6 6.0 21.2 0.0 0.0 0.2 0.0 0.0 0.2 0.5 0.4 0.8 0.0 0.0 21.7 0.0 0.0 1.1 6.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 32.8 1.0 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.8 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 20.8 23.0 19.9 19.0 20.2 21.6 19.8 20.7 21.3 19.3 21.2 0.6 6.4 3.6 16.3 0.6 0.5 4.9 0.2 1.8 9.6 2.4 7.0 27.5 8.6 0.7 14.7 0.0 0.1 0.0 0.2 58.7 13.9 0.4 3.4 7.4 2.4 4.8 2.7 10.8 8.9 0.3 11.2 3.1 0.5 0.0 67.8 11.4 175.7 0.1 5.0 4.9 0.2 0.0 5.3 1.2 2.1 24.8 1.2 1.8 4.7 0.0 54.5 0.0 27.2 13.7 5.0 1.2 69.6 0.7 1.1 0.2 174.4 1.7 3.1 13.1 22.3 11.3 0.2 0.2 0.5 0.3 0.3 0.7 14.5 0.7 1.3 RGS16 "A28-RGS14, RGS-r" ENSG00000143333 "Regulator of G protein signaling 16" O15492 1 182598623-182604389 "Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 132.2;thyroid gland: 103.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 535.4;Muller glia cells: 265.9;Smooth muscle cells: 581.5;Theca cells: 253.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "thalamus: 132.2" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 9.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 109.3;NB-4: 60.7;SCLC-21H: 109.6;U-266/70: 124.0;U-698: 162.8" "Region enriched" "Detected in all" 5 "thalamus: 79.9" "Group enriched" "Detected in many" 7 "midbrain: 76.5;pons: 68.5;thalamus: 124.2" "HPA053250, HPA055824" Uncertain Approved Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA053250: AB_2682090, HPA055824: AB_2682934" "unprognostic (4.03e-2)" "unprognostic (6.08e-2)" "unprognostic (4.87e-2)" "unprognostic (1.08e-2)" "unprognostic (2.27e-2)" "unprognostic (2.38e-2)" "unprognostic (3.55e-2)" "unprognostic (2.01e-2)" "unprognostic (2.10e-1)" "unprognostic (4.69e-2)" "unprognostic (2.04e-2)" "unprognostic (8.39e-2)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.93e-2)" "unprognostic (3.65e-2)" "unprognostic (9.07e-3)" "unprognostic (5.39e-2)" 39.6 10.4 22.7 11.7 10.0 4.8 7.8 9.6 9.9 2.7 16.5 13.1 2.8 3.3 4.8 6.2 12.1 16.5 9.2 7.5 47.0 15.4 13.1 26.7 17.9 17.5 71.3 4.0 7.8 5.7 50.4 12.1 13.2 4.8 5.3 60.4 6.4 6.3 6.0 5.6 6.8 12.0 12.1 14.3 8.8 1.0 132.2 8.6 103.6 8.9 6.6 38.3 2.9 17.8 0.8 0.1 6.4 0.0 1.0 0.2 48.6 0.2 1.7 0.0 0.1 0.1 0.3 109.3 0.5 0.0 0.0 0.5 11.9 1.0 0.1 12.5 8.8 11.5 1.2 0.0 1.8 18.4 9.5 2.5 17.8 0.0 0.7 0.0 0.0 3.9 0.5 18.6 0.0 12.3 0.6 60.7 34.2 1.0 3.5 0.2 35.1 26.2 0.1 5.1 109.6 11.5 0.2 9.1 0.2 6.4 3.6 14.6 0.1 0.3 2.4 3.1 5.5 124.0 6.1 162.8 0.6 11.8 5.8 2.6 0.3 0.6 0.3 0.4 0.6 4.7 4.3 0.5 0.5 2.2 1.9 0.6 1.2 2.6 0.9 9.7 2.9 1.1 22.7 10.0 9.6 9.9 7.5 47.0 17.5 71.3 13.2 12.1 132.2 17.8 80.8 134.6 185.5 6.2 48.3 82.3 10.0 3.8 37.5 535.4 25.8 94.5 25.7 0.0 18.7 9.2 18.8 8.5 28.7 11.2 0.0 1.6 0.4 21.4 41.5 181.8 50.5 20.4 0.1 2.4 201.9 103.7 17.3 30.5 71.8 0.5 18.9 2.6 19.1 32.0 8.3 12.1 16.2 2.8 116.7 0.0 0.3 18.4 81.8 0.0 11.9 265.9 0.0 0.0 0.7 2.9 4.7 0.4 64.3 12.4 1.1 0.8 2.6 46.9 65.7 47.3 581.5 0.2 2.1 37.0 63.1 34.5 33.5 253.5 6.4 9.7 RGS2 G0S8 ENSG00000116741 "Regulator of G protein signaling 2" P41220 1 192809039-192812275 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Translation regulation" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 1871.8;Langerhans cells: 637.8;Macrophages: 621.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 3268.4;neutrophil: 4374.2" "Lineage enriched" "Detected in all" 8 "granulocytes: 4374.2" "Cell line enhanced" "Detected in many" "hTCEpi: 141.8;hTERT-HME1: 96.8;Karpas-707: 94.0;PC-3: 226.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013385 Supported Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 60: Granulocytes - Receptor signaling" Cytosol "HPA013385: AB_2668827" "prognostic favorable (2.43e-4)" "unprognostic (9.75e-2)" "unprognostic (1.28e-3)" "unprognostic (4.43e-2)" "unprognostic (1.79e-1)" "unprognostic (1.93e-1)" "unprognostic (2.09e-3)" "unprognostic (1.29e-2)" "unprognostic (2.59e-1)" "unprognostic (2.79e-2)" "unprognostic (1.36e-1)" "unprognostic (6.49e-2)" "prognostic unfavorable (2.90e-5)" "prognostic unfavorable (3.56e-4)" "unprognostic (1.16e-1)" "unprognostic (4.34e-3)" "unprognostic (1.01e-3)" 129.3 353.8 36.4 241.4 40.7 565.0 126.8 41.8 82.6 67.2 56.7 328.5 142.7 217.4 96.0 256.2 149.2 189.5 73.0 43.6 47.7 53.6 66.3 123.6 37.1 50.3 43.9 137.4 513.3 12.5 198.7 100.1 46.0 182.2 110.1 36.9 27.5 222.4 10.0 37.3 104.9 505.9 41.0 192.1 113.4 18.8 47.5 47.3 22.8 63.7 17.3 259.8 71.7 42.1 0.0 20.1 25.4 2.4 48.9 7.7 1.5 9.9 12.4 3.2 3.4 17.9 11.8 1.7 2.8 9.3 2.5 9.7 16.7 17.5 2.9 2.6 12.3 4.8 12.9 0.4 21.5 12.1 2.8 8.1 141.8 6.5 96.8 18.1 23.9 9.1 4.4 94.0 10.0 0.3 6.6 16.8 34.0 1.9 226.6 6.7 5.9 5.4 16.9 16.3 9.4 47.4 7.1 0.5 11.8 26.0 0.7 6.0 6.7 4.8 4.5 5.2 5.2 55.4 1.7 5.3 67.3 2.4 17.8 3268.4 517.9 754.6 14.3 200.8 32.1 6.4 10.2 10.4 118.8 3.3 5.2 6.6 4374.2 2.3 362.7 16.0 6.7 310.2 36.4 40.7 41.8 82.6 43.6 47.7 50.3 43.9 46.0 41.0 47.5 42.1 22.3 51.3 195.9 6.8 187.2 42.3 47.3 45.0 6.2 18.7 138.5 44.1 69.4 7.2 46.1 136.1 18.8 227.6 145.1 27.0 0.0 33.5 24.6 6.9 51.5 38.6 349.2 3.2 6.6 30.3 24.5 125.8 38.7 7.5 1871.8 2.3 18.5 3.1 374.4 21.9 8.4 96.9 42.7 345.0 637.8 18.3 16.4 621.2 88.9 8.4 305.0 41.5 25.7 3.5 2.4 14.8 60.3 62.8 135.9 36.3 141.5 2.5 20.4 39.0 0.0 61.4 55.5 4.2 16.9 6.1 31.1 124.2 346.1 16.6 32.3 11.3 RGS4 SCZD9 ENSG00000117152 "Regulator of G protein signaling 4" P49798 1 163068775-163076802 "Disease related genes, Predicted intracellular proteins" "Signal transduction inhibitor" Schizophrenia "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 34.6;brain: 120.6" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 51.6;Excitatory neurons: 115.4;Inhibitory neurons: 59.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 120.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "hTERT-RPE1: 527.4;LHCN-M2: 244.2;SH-SY5Y: 429.5;TIME: 959.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030802 Approved Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA030802: AB_10602295" "unprognostic (1.03e-1)" "unprognostic (1.84e-1)" "unprognostic (3.02e-2)" "unprognostic (6.84e-2)" "prognostic unfavorable (2.62e-4)" "unprognostic (8.26e-2)" "unprognostic (1.27e-1)" "unprognostic (5.34e-3)" "unprognostic (1.82e-1)" "unprognostic (6.45e-2)" "unprognostic (2.12e-2)" "unprognostic (8.47e-2)" "prognostic unfavorable (3.97e-4)" "prognostic unfavorable (1.92e-4)" "unprognostic (1.00e-1)" "unprognostic (8.33e-2)" "unprognostic (2.30e-2)" 8.2 34.6 35.6 3.0 46.7 0.0 1.7 0.0 120.6 5.9 0.0 4.3 4.2 7.8 1.2 9.7 7.3 18.3 8.7 49.3 42.2 1.9 4.0 3.0 3.7 0.0 5.2 2.2 4.7 2.3 14.3 1.6 2.0 4.7 2.5 6.7 0.8 6.5 0.4 0.3 2.8 4.7 0.0 1.7 8.4 3.0 0.0 1.8 3.1 1.4 0.4 5.9 1.4 39.7 0.3 0.0 1.2 7.2 25.1 115.9 0.2 77.8 92.1 12.6 31.9 0.0 0.3 0.3 35.6 50.2 0.5 0.2 0.0 0.1 42.2 0.4 0.1 0.3 0.0 0.0 11.0 0.2 0.2 19.0 0.0 123.0 14.3 527.4 127.5 0.0 0.1 0.6 244.2 0.0 0.0 0.5 6.5 0.0 9.6 0.1 0.0 0.4 0.0 0.0 2.9 429.5 0.0 0.1 0.2 4.0 0.1 0.1 959.6 91.5 5.2 19.1 129.5 0.1 0.1 0.3 11.4 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.6 46.7 0.0 120.6 49.3 42.2 0.0 5.2 2.0 0.0 0.0 39.7 0.8 0.0 0.0 15.7 0.0 0.3 1.7 0.1 0.0 4.3 0.7 0.0 0.7 0.0 0.7 0.0 0.0 0.2 0.1 0.1 0.0 0.3 12.6 0.5 16.9 2.6 51.6 0.0 115.4 0.2 0.1 20.2 0.0 0.4 0.0 1.1 1.1 0.0 0.4 0.0 59.9 0.0 0.0 0.0 0.5 3.8 0.0 0.1 0.0 13.1 0.0 15.7 0.0 13.0 13.0 2.7 0.1 0.0 0.0 0.5 0.0 0.0 0.7 1.6 0.0 0.2 17.0 0.1 0.6 0.5 0.3 0.1 0.6 0.1 0.1 0.3 RILPL2 "FLJ30380, FLJ32372, MGC7036" ENSG00000150977 "Rab interacting lysosomal protein like 2" Q969X0 12 123415039-123436684 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "bone marrow: 116.2" "Cell type enhanced" "Detected in many" "B-cells: 149.8;Macrophages: 288.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 103.8;NB-4: 235.2;THP-1: 149.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028958 Approved Supported Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 41: Macrophages - Immune response" Cytosol "HPA028958: AB_10602124" "unprognostic (1.94e-3)" "unprognostic (3.29e-3)" "unprognostic (1.02e-1)" "prognostic favorable (5.24e-7)" "unprognostic (2.62e-2)" "unprognostic (8.89e-2)" "unprognostic (2.18e-1)" "unprognostic (2.69e-2)" "unprognostic (4.08e-2)" "unprognostic (1.55e-1)" "unprognostic (1.97e-1)" "unprognostic (2.10e-2)" "unprognostic (5.90e-3)" "unprognostic (1.11e-1)" "unprognostic (8.57e-2)" "unprognostic (2.10e-1)" "unprognostic (4.74e-2)" 21.4 7.5 9.3 27.4 9.7 116.2 15.8 8.2 11.1 26.3 14.2 6.3 5.4 19.3 11.2 7.6 18.4 15.7 8.2 9.5 10.2 18.6 11.9 24.1 23.8 9.7 9.7 13.1 8.0 11.4 3.5 14.4 9.2 18.6 5.8 1.4 23.2 23.7 4.6 5.5 6.5 13.8 9.1 26.7 10.3 3.2 10.3 15.2 27.8 5.9 17.7 20.5 7.0 8.6 14.2 12.7 4.6 21.8 29.8 23.6 13.3 16.1 41.0 15.3 12.7 16.2 5.5 7.6 15.2 25.1 8.4 9.2 10.3 12.3 14.2 29.1 9.8 103.8 9.9 24.2 33.2 81.2 50.6 18.3 9.3 16.0 11.6 19.8 15.7 20.4 11.1 3.8 12.4 9.4 28.0 235.2 2.9 4.5 13.9 19.8 14.1 15.4 16.0 26.1 1.0 6.7 21.9 0.7 16.9 9.2 19.5 149.0 17.0 12.5 9.2 22.8 9.9 6.2 8.0 18.2 12.3 55.1 5.3 98.6 133.3 159.3 24.0 106.0 22.4 55.8 51.1 42.7 98.7 41.9 19.7 22.5 176.8 22.4 121.5 46.7 67.7 63.8 9.3 9.7 8.2 11.1 9.5 10.2 9.7 9.7 9.2 9.1 10.3 8.6 75.7 35.3 75.2 7.2 149.8 24.5 68.4 67.8 32.5 1.4 45.3 35.9 5.1 17.2 43.3 22.0 2.1 10.1 75.0 2.4 25.4 20.1 2.1 51.9 24.8 73.2 4.2 24.2 7.5 21.0 5.4 28.2 9.2 27.0 62.6 8.4 84.3 13.3 72.9 1.7 2.6 8.1 0.0 112.5 129.7 2.7 50.4 288.7 37.4 10.3 117.8 18.7 42.2 5.5 2.3 22.7 6.4 66.2 25.7 82.6 1.5 63.5 47.1 2.1 6.6 13.1 30.1 1.4 13.0 12.5 15.3 8.1 92.5 10.1 4.8 69.2 RIOK1 "AD034, bA288G3.1, FLJ30006, RRP10" ENSG00000124784 "RIO kinase 1" Q9BRS2 6 7389793-7418037 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017866, HPA051446" Enhanced Supported Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA017866: AB_2669670, HPA051446: AB_2681488" "unprognostic (2.33e-2)" "unprognostic (1.24e-1)" "unprognostic (2.38e-1)" "unprognostic (1.03e-2)" "unprognostic (1.16e-1)" "unprognostic (1.51e-1)" "prognostic unfavorable (3.41e-5)" "unprognostic (2.23e-1)" "prognostic unfavorable (4.43e-4)" "unprognostic (3.45e-2)" "unprognostic (1.47e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (5.85e-5)" "unprognostic (2.33e-1)" "unprognostic (2.09e-1)" "unprognostic (6.12e-3)" "unprognostic (2.59e-2)" 12.1 9.3 4.1 10.8 4.1 20.6 11.0 5.0 5.3 10.0 3.7 7.9 6.5 10.5 5.2 11.4 8.2 7.5 8.0 4.2 5.1 6.4 7.9 7.1 14.0 4.7 5.1 10.9 10.2 7.3 4.7 11.4 4.6 8.0 8.6 7.3 7.0 8.1 11.5 9.1 6.3 10.8 4.2 9.4 7.0 19.9 4.5 15.7 7.3 10.3 15.9 14.9 7.6 4.7 20.4 11.7 18.3 45.8 27.0 22.6 28.7 25.6 16.6 22.1 18.5 33.1 10.0 51.8 43.3 19.7 19.4 20.3 45.7 19.5 29.0 35.8 49.6 28.3 18.3 39.4 23.0 81.5 37.5 17.2 27.2 24.1 50.4 11.5 20.1 38.6 72.1 12.3 21.0 26.7 56.8 50.2 39.6 36.3 26.1 42.9 23.3 56.6 13.8 19.9 60.8 30.4 20.8 13.3 41.6 48.4 18.9 28.4 19.9 24.4 18.9 17.5 38.3 17.1 33.0 75.7 7.7 44.0 38.7 12.0 11.5 9.0 14.9 15.6 18.0 21.5 15.4 15.9 20.5 23.0 17.8 19.2 2.3 26.7 14.0 17.3 16.2 11.3 4.1 4.1 5.0 5.3 4.2 5.1 4.7 5.1 4.6 4.2 4.5 4.7 22.2 6.4 26.4 5.5 27.5 52.8 32.3 29.5 38.1 10.0 18.9 22.0 22.8 4.3 35.2 7.3 10.4 34.1 25.3 9.9 3.9 15.9 74.8 14.9 28.4 24.8 7.2 17.9 10.2 11.7 34.7 29.8 16.8 19.1 33.6 13.4 19.2 10.2 22.6 5.0 12.0 17.4 20.3 11.2 25.1 12.5 19.9 19.7 17.8 11.2 15.1 8.9 6.2 13.0 8.4 12.2 8.2 19.9 27.0 33.7 7.1 9.3 20.9 13.7 19.7 33.8 23.9 58.9 75.4 33.7 64.8 27.9 29.0 23.9 16.9 23.8 RIPK2 "CARD3, CARDIAK, RICK, RIP2" ENSG00000104312 "Receptor interacting serine/threonine kinase 2" O43353 8 89757806-89791064 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 156.1;Langerhans cells: 121.3;Macrophages: 105.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 49.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015273, HPA016499" Approved Enhanced Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" Cytosol "HPA015273: AB_1856299, HPA016499: AB_1856300" "unprognostic (1.20e-1)" "unprognostic (1.02e-2)" "unprognostic (2.35e-1)" "unprognostic (3.82e-2)" "unprognostic (1.67e-1)" "unprognostic (6.20e-2)" "unprognostic (1.43e-3)" "prognostic unfavorable (6.33e-5)" "unprognostic (2.06e-1)" "unprognostic (7.80e-2)" "prognostic unfavorable (5.00e-6)" "unprognostic (6.39e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.84e-2)" "unprognostic (5.08e-2)" "unprognostic (1.05e-2)" "prognostic favorable (8.05e-4)" 4.1 1.6 4.0 5.6 4.0 8.9 5.1 4.0 5.5 4.7 3.3 2.9 1.7 5.5 2.4 3.0 2.7 9.4 4.4 4.1 5.5 3.7 5.6 6.0 6.5 4.6 4.0 2.5 4.4 4.2 1.9 4.7 5.1 5.3 2.9 1.5 5.0 2.7 0.6 4.2 2.4 5.7 5.3 4.8 2.9 2.9 3.7 2.8 4.2 1.3 6.7 9.4 2.6 6.0 17.8 6.0 3.2 4.9 7.9 10.8 5.5 19.2 36.1 10.7 13.6 4.6 9.7 14.4 28.0 11.7 7.6 4.2 8.9 6.9 20.2 8.7 8.0 11.9 2.8 5.5 22.2 4.5 5.8 8.8 5.6 15.6 49.8 11.4 11.4 0.0 5.4 4.7 10.2 3.4 0.0 9.6 1.5 8.4 14.4 3.2 4.1 7.5 26.1 8.4 0.4 3.1 4.7 12.6 10.0 4.0 12.0 5.6 10.1 6.5 6.0 11.2 9.1 8.9 4.2 8.8 16.2 0.4 4.3 13.7 6.6 23.2 3.5 12.5 4.1 7.6 5.4 4.6 8.1 4.8 4.9 5.4 5.1 4.4 14.9 2.6 1.3 4.6 4.0 4.0 4.0 5.5 4.1 5.5 4.6 4.0 5.1 5.3 3.7 6.0 19.3 35.3 18.1 25.5 29.8 57.6 33.7 13.3 16.5 2.1 17.2 8.9 5.2 4.3 22.9 3.7 0.0 13.3 32.8 2.8 5.9 80.1 6.6 82.3 23.7 15.0 0.0 9.9 12.9 60.8 45.7 27.3 9.7 156.1 43.1 7.1 6.1 3.2 41.7 3.3 9.1 5.4 24.4 32.4 121.3 2.5 7.8 105.1 19.6 15.0 42.1 12.1 8.2 15.6 12.8 50.0 2.7 6.0 22.0 59.2 2.2 10.4 11.6 0.3 13.1 19.2 19.6 7.9 12.8 14.7 48.3 83.7 30.4 7.5 8.1 49.5 RNASEL "PRCA1, RNS4" ENSG00000135828 "Ribonuclease L" Q05823 1 182573634-182589256 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense" "Endonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002633, CAB010906" Approved Supported Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB010906: AB_477444, HPA002633: AB_1856314" "unprognostic (3.46e-2)" "unprognostic (9.10e-2)" "unprognostic (7.74e-2)" "unprognostic (1.13e-1)" "unprognostic (9.29e-2)" "unprognostic (1.57e-1)" "unprognostic (6.14e-2)" "unprognostic (1.42e-1)" "unprognostic (3.89e-2)" "unprognostic (1.93e-2)" "unprognostic (1.01e-1)" "unprognostic (2.02e-1)" "unprognostic (5.43e-2)" "unprognostic (1.99e-1)" "unprognostic (1.44e-1)" "unprognostic (2.59e-1)" "unprognostic (1.81e-1)" 5.6 6.4 3.2 8.8 3.5 3.6 5.9 3.4 3.9 6.6 3.7 8.1 7.0 6.5 9.6 6.2 5.2 6.9 3.4 2.9 3.4 6.2 3.5 6.9 9.6 3.4 3.5 11.3 3.1 7.9 5.4 6.9 3.6 7.2 9.0 5.7 5.0 8.3 2.0 5.4 8.0 7.1 2.8 8.9 7.8 2.2 3.6 8.0 9.1 4.5 9.9 6.0 6.3 3.3 2.6 3.6 1.5 0.6 7.9 13.7 2.8 4.9 6.1 4.9 4.5 2.1 5.6 5.6 8.4 5.6 2.2 4.7 3.6 5.1 1.9 4.5 3.1 6.6 1.3 0.3 4.1 12.4 12.5 9.8 11.4 2.6 0.7 3.1 2.1 8.2 2.4 4.2 4.3 3.8 3.6 5.1 1.2 8.4 1.0 5.3 1.2 2.9 5.2 3.4 0.7 0.2 4.4 5.3 4.3 3.9 5.4 13.6 2.8 2.5 2.0 2.7 2.7 3.7 1.3 0.7 4.0 7.5 3.8 41.7 14.8 53.1 9.4 15.8 12.4 10.3 11.1 10.1 12.4 7.9 17.3 12.8 55.3 10.9 30.3 14.7 10.0 10.5 3.2 3.5 3.4 3.9 2.9 3.4 3.4 3.5 3.6 2.8 3.6 3.3 4.5 6.4 4.2 5.2 6.5 1.0 2.9 4.9 1.2 4.3 2.8 2.4 1.3 1.5 9.0 3.7 4.2 4.2 8.2 14.8 7.9 6.7 0.0 2.5 9.6 5.1 2.4 4.8 4.2 1.8 3.7 6.4 7.7 3.4 5.7 5.5 3.9 1.6 6.2 1.7 6.6 9.3 8.2 9.7 1.2 0.8 2.8 5.8 0.0 1.9 7.3 8.7 5.2 6.0 3.6 2.2 3.2 6.4 2.7 3.5 7.2 7.3 9.1 6.1 19.7 5.8 5.2 0.4 0.9 4.5 1.0 2.6 7.5 12.1 4.0 4.6 RNF123 "FLJ12565, KPC1" ENSG00000164068 "Ring finger protein 123" Q5XPI4 3 49689538-49721529 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 156.1;tongue: 112.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 52.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065983, HPA071879" Supported Approved Cytosol NA NA 140000 "Cluster 37: B-cells - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" Cytosol "HPA065983: AB_2685592, HPA071879: AB_2686468" "unprognostic (2.68e-1)" "unprognostic (3.34e-1)" "unprognostic (2.67e-1)" "unprognostic (1.04e-1)" "unprognostic (2.21e-1)" "unprognostic (9.51e-2)" "unprognostic (2.04e-1)" "unprognostic (3.75e-1)" "unprognostic (4.08e-1)" "unprognostic (1.07e-1)" "unprognostic (7.51e-2)" "unprognostic (5.03e-3)" "prognostic favorable (1.33e-8)" "unprognostic (5.69e-2)" "unprognostic (1.74e-1)" "unprognostic (7.22e-2)" "unprognostic (3.83e-1)" 13.0 19.0 18.9 9.0 19.2 34.6 12.5 18.5 23.9 13.1 21.0 17.8 19.5 14.7 10.5 13.4 12.5 9.7 27.8 19.6 16.5 22.0 57.7 12.3 10.4 17.5 16.9 11.6 13.5 16.3 17.4 9.4 17.2 14.6 6.8 6.0 14.4 9.2 156.1 14.5 18.2 9.3 14.7 17.9 17.9 23.7 18.0 13.7 14.6 112.0 7.3 14.2 12.0 17.9 9.7 12.6 15.5 16.2 23.2 13.9 17.1 12.1 15.9 15.0 16.0 14.1 16.1 23.2 10.9 17.6 13.3 11.8 11.6 18.1 10.0 15.8 15.0 19.7 27.8 31.6 23.1 19.3 19.8 17.6 17.9 14.4 16.5 14.8 16.2 23.0 20.0 20.0 13.2 14.1 19.8 30.7 8.2 11.5 21.0 9.3 9.7 24.4 21.5 16.4 10.6 20.8 16.4 14.4 18.7 8.7 15.4 33.0 16.2 13.4 16.3 11.9 14.9 26.4 28.4 9.5 19.2 23.6 20.5 8.9 6.9 5.6 6.7 6.2 4.0 7.1 4.5 4.1 5.5 7.0 5.3 5.0 4.0 5.5 6.8 7.9 3.6 3.8 18.9 19.2 18.5 23.9 19.6 16.5 17.5 16.9 17.2 14.7 18.0 17.9 7.1 9.6 5.3 16.3 6.5 2.3 3.1 4.7 1.8 8.6 7.1 6.1 1.1 11.5 5.8 3.7 4.2 6.8 9.3 10.4 5.9 5.3 13.3 8.1 5.8 5.9 6.7 52.4 18.0 5.5 4.6 5.9 11.2 7.5 7.0 9.5 10.0 29.8 5.6 6.7 14.6 6.1 10.2 9.6 1.4 16.5 7.5 6.0 3.6 5.6 6.3 5.4 7.2 7.5 7.2 7.2 6.3 5.7 7.0 5.0 19.2 10.2 5.4 8.9 0.0 7.6 5.6 10.7 8.9 4.6 3.0 8.5 6.0 7.5 6.9 4.1 RNF148 MGC35222 ENSG00000235631 "Ring finger protein 148" Q8N7C7 7 122701668-122702922 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 49.3" "Cell type enriched" "Detected in some" 6 "Early spermatids: 405.2" "Not detected" "Not detected" "Region enriched" "Detected in some" 6 "cerebellum: 9.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 2.8;MCF7: 1.1" "Not detected" "Not detected" HPA045587 Approved Cytosol NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "HPA045587: AB_10963695" "unprognostic (1.75e-1)" "unprognostic (2.15e-1)" "unprognostic (3.19e-1)" "unprognostic (1.21e-2)" "unprognostic (2.85e-1)" "unprognostic (3.23e-2)" "unprognostic (1.04e-2)" "unprognostic (9.81e-2)" "unprognostic (8.48e-2)" "unprognostic (2.14e-2)" "unprognostic (2.18e-1)" "unprognostic (2.37e-1)" "unprognostic (3.33e-2)" "unprognostic (2.24e-2)" "unprognostic (1.24e-1)" "unprognostic (6.63e-2)" "unprognostic (1.09e-1)" 0.2 0.2 0.0 0.0 0.2 0.0 0.2 9.9 1.7 0.2 0.2 0.1 0.0 0.6 0.1 0.0 0.2 0.1 0.2 0.2 0.1 0.3 0.3 0.4 0.0 0.0 0.2 0.1 0.3 0.0 0.2 0.0 0.6 0.4 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 49.3 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 2.8 0.0 1.1 0.0 0.0 0.3 0.6 0.3 0.0 0.0 0.7 0.0 0.2 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 9.9 1.7 0.2 0.1 0.0 0.2 0.6 0.0 0.1 0.7 2.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.1 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 405.2 0.5 0.5 0.5 0.0 0.0 0.0 1.0 0.1 0.1 0.0 0.8 0.0 0.1 1.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 62.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 1.9 0.0 0.1 0.0 0.2 0.0 0.0 6.6 0.2 0.1 3.9 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.1 RNF180 ENSG00000164197 "Ring finger protein 180" Q86T96 5 64165843-64372869 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 25.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 90.5;Inhibitory neurons: 151.6;Oligodendrocyte precursor cells: 162.3" "Cancer enhanced" "Detected in many" "glioma: 7.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 6 "RPMI-8226: 29.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006897 Approved Approved Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA006897: AB_1856348" "unprognostic (7.46e-2)" "unprognostic (3.90e-3)" "unprognostic (3.19e-2)" "unprognostic (8.62e-2)" "unprognostic (2.45e-1)" "unprognostic (2.72e-1)" "unprognostic (5.57e-2)" "unprognostic (2.38e-2)" "unprognostic (1.08e-1)" "unprognostic (1.69e-1)" "unprognostic (3.37e-3)" "unprognostic (3.68e-2)" "prognostic favorable (6.81e-5)" "unprognostic (2.01e-2)" "unprognostic (3.35e-2)" "unprognostic (1.81e-2)" "unprognostic (9.81e-3)" 5.4 5.1 3.2 1.5 3.9 0.3 3.6 2.6 5.1 4.1 2.9 3.3 1.7 7.7 7.7 4.2 4.9 4.2 7.0 2.8 8.2 8.1 4.5 3.7 1.3 3.9 5.8 7.6 4.2 25.3 3.5 0.6 4.7 7.3 1.3 6.0 4.6 10.6 2.7 4.1 1.4 5.7 4.4 3.0 2.6 3.4 6.6 0.7 14.0 4.1 0.9 3.3 2.3 4.5 0.0 0.1 1.4 0.0 0.0 0.0 0.3 1.2 0.5 1.2 0.7 0.0 0.1 0.0 0.1 0.9 0.7 0.2 0.0 0.5 0.2 0.0 0.1 0.4 0.0 0.0 0.5 0.0 0.3 0.1 3.0 0.0 0.1 4.8 0.0 0.0 0.0 0.0 2.5 0.4 0.0 0.0 0.6 0.0 1.4 0.1 3.7 29.4 2.1 0.3 0.3 0.1 0.0 0.3 0.0 1.8 1.5 0.1 0.1 0.0 3.5 0.1 3.3 0.0 0.0 0.0 0.6 0.0 3.9 1.2 0.6 1.7 0.6 0.2 0.9 0.5 1.0 1.1 0.2 0.8 1.4 1.3 1.0 0.8 0.3 0.4 0.7 0.0 3.2 3.9 2.6 5.1 2.8 8.2 3.9 5.8 4.7 4.4 6.6 4.5 9.5 16.0 12.3 51.6 0.5 4.6 8.9 1.3 7.4 16.6 8.1 4.2 10.9 10.0 4.9 16.5 14.6 0.0 0.0 0.0 7.9 5.8 12.5 14.2 6.1 6.3 1.2 0.0 90.5 2.6 0.1 7.9 6.1 32.9 0.0 5.7 14.3 5.9 0.1 11.8 151.6 1.9 0.0 0.6 1.1 8.8 34.5 0.5 5.4 32.8 0.0 30.1 0.0 162.3 50.1 3.1 2.7 25.2 0.0 6.4 1.2 15.9 1.9 16.9 39.5 24.2 20.4 18.9 12.0 2.9 7.4 0.0 0.3 4.1 1.6 4.5 RNF19B "FLJ90005, IBRDC3" ENSG00000116514 "Ring finger protein 19B" Q6ZMZ0 1 32936445-32964809 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 79.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.9" "Lineage enriched" "Detected in all" 8 "granulocytes: 16.9" "Cell line enhanced" "Detected in all" "Daudi: 107.6;Karpas-707: 124.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049587, HPA063640" Approved Approved Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Cytosol "HPA049587: AB_2680826, HPA063640: " "unprognostic (2.83e-2)" "unprognostic (1.77e-2)" "unprognostic (1.86e-2)" "unprognostic (2.01e-1)" "unprognostic (1.78e-2)" "prognostic favorable (3.39e-4)" "prognostic unfavorable (5.41e-6)" "unprognostic (8.78e-2)" "unprognostic (5.02e-1)" "unprognostic (1.69e-1)" "unprognostic (9.85e-2)" "unprognostic (1.38e-1)" "prognostic favorable (4.39e-5)" "unprognostic (2.58e-2)" "unprognostic (4.93e-2)" "unprognostic (3.30e-1)" "unprognostic (1.23e-2)" 14.5 19.1 10.7 24.3 9.6 74.1 10.9 14.5 10.7 16.8 7.6 23.3 25.0 15.0 5.0 35.3 12.3 17.4 10.4 9.9 12.1 21.1 11.3 21.1 17.7 10.7 9.6 9.7 9.2 11.5 7.9 14.9 11.8 11.0 25.8 18.9 15.4 8.9 16.2 22.6 21.7 18.0 11.6 15.1 13.1 79.0 10.8 13.0 9.0 11.1 30.6 30.1 20.9 11.6 18.7 14.3 11.9 11.3 7.1 9.6 79.5 8.5 10.0 14.7 15.6 16.8 54.9 107.6 14.2 10.7 18.2 26.5 14.3 19.8 13.3 39.6 9.5 9.2 10.5 16.9 22.5 14.7 19.0 7.9 36.3 32.5 39.3 17.2 31.9 10.3 11.7 124.8 14.5 6.1 9.6 18.4 19.2 21.1 15.8 12.7 17.3 11.3 11.5 26.4 18.9 9.6 27.0 9.1 63.1 29.1 8.0 20.8 35.1 8.1 11.5 21.1 15.1 29.6 16.1 38.0 11.9 14.7 12.5 6.1 2.0 4.0 1.6 1.9 1.3 1.2 1.4 0.7 1.4 1.5 0.4 0.6 16.9 1.0 1.7 0.6 1.7 0.8 10.7 9.6 14.5 10.7 9.9 12.1 10.7 9.6 11.8 11.6 10.8 11.6 20.6 12.8 4.4 5.5 8.7 46.1 27.0 26.7 24.5 4.6 15.8 11.7 16.2 10.0 9.9 7.3 2.1 12.6 14.6 48.0 1.9 12.9 34.8 25.4 7.3 15.3 11.3 5.2 9.7 11.5 6.3 8.4 13.3 36.9 4.5 3.2 7.1 4.8 13.5 3.3 9.8 22.1 6.1 20.9 37.7 26.3 2.1 42.4 5.4 19.7 39.5 2.8 2.1 7.5 6.6 25.7 31.9 3.8 4.6 34.2 38.6 9.2 14.4 7.7 0.0 5.9 9.6 34.7 16.3 23.9 32.5 7.4 10.3 2.3 16.3 41.7 RNF207 "C1orf188, FLJ32096, FLJ46380" ENSG00000158286 "Ring finger protein 207" Q6ZRF8 1 6205475-6221299 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 34.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 31.8;Basal respiratory cells: 31.7;Club cells: 28.3;Urothelial cells: 37.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 17.2;HaCaT: 7.6;HeLa: 7.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA028378, HPA042535" Uncertain Approved Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA028378: AB_10601157, HPA042535: AB_2678042" "unprognostic (5.53e-3)" "unprognostic (1.23e-1)" "unprognostic (1.62e-2)" "unprognostic (4.46e-2)" "unprognostic (4.84e-2)" "unprognostic (5.91e-3)" "unprognostic (9.48e-2)" "unprognostic (1.22e-1)" "unprognostic (1.57e-2)" "unprognostic (8.74e-2)" "unprognostic (9.93e-2)" "unprognostic (5.17e-2)" "prognostic unfavorable (1.92e-4)" "unprognostic (3.76e-2)" "unprognostic (2.93e-2)" "unprognostic (1.89e-1)" "unprognostic (8.10e-3)" 3.3 3.3 3.2 1.3 3.2 0.0 3.1 4.0 4.2 9.5 5.9 5.8 2.0 4.3 1.5 5.9 7.9 0.9 34.7 3.2 3.1 9.8 7.6 1.7 0.9 3.7 2.9 2.5 6.9 1.2 5.5 1.2 3.7 11.8 1.4 2.1 6.7 3.8 1.7 1.2 4.4 1.2 2.6 1.4 4.1 1.2 3.2 0.5 6.7 4.2 1.3 6.3 5.4 3.0 2.6 4.5 0.4 2.9 0.2 0.3 3.1 1.3 1.0 0.2 0.3 2.2 17.2 0.2 1.3 1.1 0.0 7.6 0.4 1.0 0.1 2.8 1.7 0.1 7.0 2.2 1.3 1.7 0.1 1.1 0.2 0.0 0.0 3.8 0.1 0.3 0.7 3.6 0.1 1.8 0.2 0.3 0.2 0.3 3.8 0.0 0.7 2.9 2.2 3.9 0.4 1.1 2.8 1.5 1.1 0.7 2.7 0.1 0.5 0.0 0.8 0.4 0.0 3.9 0.5 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 3.2 3.2 4.0 4.2 3.2 3.1 3.7 2.9 3.7 2.6 3.2 3.0 2.9 9.6 3.9 2.0 1.7 0.3 31.8 31.7 6.2 4.0 4.4 4.3 19.5 14.3 28.3 18.4 2.1 15.6 0.4 8.5 0.0 15.4 0.7 2.3 6.8 2.9 3.6 0.4 13.2 9.8 6.3 4.6 17.3 2.7 0.0 1.7 1.1 3.9 1.1 3.3 13.2 15.6 10.2 0.0 0.7 0.2 0.0 1.6 0.0 0.0 2.2 7.5 0.0 3.5 1.7 19.0 3.5 1.2 1.5 21.3 9.5 3.5 10.1 16.3 6.6 1.5 5.0 0.1 2.8 3.8 0.4 5.6 1.9 2.0 6.4 37.1 RNF213 "ALO17, C17orf27, KIAA1554, KIAA1618, MYMY2, NET57" ENSG00000173821 "Ring finger protein 213" Q63HN8 17 80260866-80398786 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Ubl conjugation pathway" "Hydrolase, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 396.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 90.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003347, HPA026790" Approved Supported Cytosol NA NA 3500 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA003347: AB_1079204, HPA026790: AB_10602296" "unprognostic (8.98e-2)" "unprognostic (1.60e-1)" "unprognostic (8.97e-3)" "prognostic unfavorable (4.65e-5)" "unprognostic (7.39e-2)" "unprognostic (3.99e-2)" "unprognostic (2.23e-2)" "unprognostic (1.52e-1)" "unprognostic (4.57e-2)" "unprognostic (3.85e-1)" "unprognostic (1.96e-2)" "unprognostic (1.12e-1)" "unprognostic (1.52e-3)" "unprognostic (8.92e-2)" "unprognostic (1.13e-2)" "unprognostic (1.40e-1)" "unprognostic (4.56e-2)" 7.4 9.9 6.8 18.6 12.9 25.6 7.0 9.0 11.3 8.0 13.0 9.0 8.7 7.8 8.7 7.1 8.6 10.7 6.5 5.1 6.9 10.5 6.2 13.2 17.9 23.5 11.4 9.0 7.8 34.2 6.6 10.0 18.3 7.1 7.8 12.0 10.8 6.8 6.6 8.8 10.6 9.1 13.8 18.7 11.1 3.4 16.5 20.2 11.0 7.6 14.5 11.0 7.1 17.3 40.1 69.7 6.9 4.9 24.4 37.0 5.1 9.9 21.4 43.7 37.1 7.5 18.1 2.6 8.3 20.8 46.6 22.7 9.3 12.9 14.7 90.8 4.3 6.3 29.9 13.3 10.5 6.7 6.2 20.5 8.6 24.6 10.6 13.7 34.3 28.3 11.8 14.5 16.5 9.7 26.7 2.8 5.1 7.5 16.0 18.0 15.9 3.1 12.1 34.1 6.6 9.2 24.1 50.3 17.3 15.3 11.6 8.2 44.5 24.2 19.0 14.4 10.3 6.3 6.3 7.0 18.2 7.6 8.9 19.5 20.8 10.4 26.2 18.5 17.5 15.3 18.6 21.6 5.4 15.5 14.6 18.2 84.5 26.1 17.1 32.0 15.4 4.8 6.8 12.9 9.0 11.3 5.1 6.9 23.5 11.4 18.3 13.8 16.5 17.3 76.1 89.8 56.9 56.8 89.9 35.8 37.2 39.2 43.3 21.2 59.9 41.7 32.6 75.8 50.3 101.2 50.1 21.0 240.8 117.4 13.7 120.3 1.4 58.7 58.9 90.7 46.0 30.3 23.6 162.4 31.5 50.8 158.0 93.4 46.7 140.7 74.3 56.4 98.0 23.5 15.5 68.2 32.6 136.5 94.9 3.7 60.9 128.9 30.2 87.1 194.6 26.1 396.5 32.2 70.4 166.1 76.2 51.6 167.6 100.8 116.3 92.2 66.2 68.5 65.7 52.3 53.7 1.4 8.2 43.0 34.4 21.8 211.6 84.7 54.9 66.5 RNF31 "FLJ10111, FLJ23501, HOIP, Paul, ZIBRA" ENSG00000092098 "Ring finger protein 31" Q96EP0 14 24146683-24160660 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 16.0;Excitatory neurons: 8.8;Gastric mucus-secreting cells: 7.7;Inhibitory neurons: 8.2;Microglial cells: 10.3;Oligodendrocyte precursor cells: 9.5;Plasma cells: 8.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "CAB009063, HPA048745" Approved Approved Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 59: Non-specific - Transcription" Cytosol "CAB009063: AB_2127706, HPA048745: AB_2680509" "unprognostic (3.58e-2)" "unprognostic (5.22e-2)" "unprognostic (2.51e-2)" "unprognostic (9.05e-2)" "unprognostic (2.52e-1)" "unprognostic (6.24e-2)" "unprognostic (9.09e-3)" "unprognostic (1.55e-2)" "unprognostic (3.11e-3)" "unprognostic (1.96e-2)" "unprognostic (1.33e-1)" "unprognostic (2.46e-1)" "unprognostic (6.21e-3)" "unprognostic (1.15e-1)" "unprognostic (2.59e-1)" "unprognostic (1.41e-2)" "unprognostic (1.99e-1)" 14.3 18.5 4.9 9.1 4.8 9.5 14.3 4.2 6.6 16.7 3.6 15.0 7.1 18.2 6.9 16.2 14.8 6.9 19.6 4.6 4.1 17.5 15.8 14.9 10.4 5.3 4.4 17.8 23.9 10.4 18.7 6.9 4.5 16.6 6.6 4.1 16.9 7.1 41.5 19.3 15.9 9.6 4.5 26.1 17.9 16.4 4.8 11.7 16.5 17.9 9.6 15.1 14.0 4.4 6.1 10.8 10.5 14.8 6.1 6.3 23.2 9.9 15.1 18.2 15.6 10.2 13.5 10.9 6.9 11.8 10.2 7.6 5.4 11.8 9.7 13.2 4.2 11.0 9.5 32.5 12.8 17.5 18.8 12.3 10.4 7.2 12.9 9.6 12.0 7.9 5.9 12.9 7.7 17.3 17.6 8.6 5.3 9.9 12.7 10.1 9.8 6.8 8.9 20.8 9.9 12.7 8.6 25.6 12.5 9.2 7.4 13.3 11.1 12.6 10.2 8.8 8.9 21.4 21.2 11.5 4.4 6.1 13.6 0.0 0.8 0.8 0.6 1.7 1.8 0.4 0.9 0.6 0.5 0.4 0.6 0.4 1.7 1.7 1.0 1.8 1.1 0.4 4.9 4.8 4.2 6.6 4.6 4.1 5.3 4.4 4.5 4.5 4.8 4.4 0.9 0.0 4.6 16.0 5.2 0.6 0.3 0.0 4.6 0.6 1.0 0.3 0.3 0.0 3.1 0.0 0.0 0.6 1.0 0.8 0.0 0.3 0.1 1.0 1.3 1.3 0.0 3.8 8.8 0.0 0.5 1.3 7.7 0.9 0.0 1.1 0.4 0.8 0.4 0.0 8.2 0.3 2.0 0.6 1.5 0.4 0.3 2.7 0.0 10.3 0.5 0.3 3.1 9.5 7.3 0.2 0.2 0.0 8.7 0.2 0.5 0.2 0.8 0.8 0.0 1.4 1.2 1.6 0.8 5.7 0.9 0.5 4.3 0.8 0.1 0.3 RO60 "SSA2, TROVE2" ENSG00000116747 "Ro60, Y RNA binding protein" P10155 1 193059454-193091777 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 53.0;Cardiomyocytes: 53.0;Cytotrophoblasts: 47.1;dendritic cells: 41.3;Extravillous trophoblasts: 45.2;Hofbauer cells: 33.4;Syncytiotrophoblasts: 48.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002835 Uncertain Supported Cytosol NA NA 50000 "Cluster 34: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA002835: AB_1857490" "unprognostic (1.91e-2)" "unprognostic (5.11e-2)" "unprognostic (3.94e-3)" "unprognostic (7.34e-2)" "unprognostic (2.34e-2)" "unprognostic (1.41e-1)" "unprognostic (3.62e-2)" "unprognostic (1.17e-1)" "unprognostic (3.77e-2)" "unprognostic (1.16e-2)" "unprognostic (8.45e-3)" "unprognostic (1.52e-1)" "unprognostic (1.05e-3)" "unprognostic (6.32e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (3.31e-4)" "unprognostic (5.62e-2)" 10.8 8.3 10.6 8.8 16.4 29.7 8.1 15.5 8.7 7.3 3.9 7.5 6.0 9.5 6.4 9.5 6.5 7.4 10.0 6.8 13.9 7.4 9.3 7.6 9.8 17.7 12.8 10.0 7.5 7.0 4.7 8.7 18.6 8.8 6.1 15.4 6.9 6.1 9.9 7.6 6.4 9.4 15.9 10.0 6.4 13.0 11.1 8.2 9.7 10.2 8.9 8.4 7.5 22.6 13.4 25.5 22.5 25.2 20.0 17.7 15.9 19.5 19.8 14.8 18.9 11.8 18.0 25.1 15.7 18.4 14.5 18.7 19.0 13.3 23.2 40.7 14.4 31.4 22.2 15.6 16.5 35.4 23.4 15.9 13.2 25.4 25.1 11.4 19.4 11.5 34.7 38.0 20.3 26.6 21.1 9.3 16.1 10.2 10.8 18.2 21.1 30.7 11.8 28.0 9.4 17.6 25.0 24.8 25.0 15.3 24.2 14.4 26.8 26.0 11.4 25.7 25.8 20.5 29.0 26.8 11.8 18.1 38.9 102.1 31.6 46.0 53.4 29.9 52.3 47.7 37.2 47.0 32.4 44.6 39.6 45.2 53.9 45.2 33.2 29.1 44.7 39.8 10.6 16.4 15.5 8.7 6.8 13.9 17.7 12.8 18.6 15.9 11.1 22.6 53.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.0 0.0 0.0 0.0 0.0 47.1 41.3 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 45.2 17.8 0.0 0.0 0.0 0.0 0.0 0.0 33.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 48.0 6.2 0.0 0.0 0.0 ROCK2 ENSG00000134318 "Rho associated coiled-coil containing protein kinase 2" O75116 2 11179759-11348330 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 280.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007459, CAB008666, HPA044109" Approved Supported Cytosol NA NA 710000 "Cluster 15: NK-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "CAB008666: AB_1622617, HPA007459: AB_1079828, HPA044109: AB_2678813" "unprognostic (4.55e-2)" "unprognostic (1.05e-2)" "unprognostic (4.18e-3)" "unprognostic (4.87e-2)" "unprognostic (1.49e-1)" "unprognostic (2.71e-1)" "unprognostic (1.39e-2)" "unprognostic (2.72e-1)" "unprognostic (3.62e-2)" "unprognostic (6.66e-2)" "unprognostic (3.83e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.57e-5)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "unprognostic (2.52e-2)" "unprognostic (3.47e-2)" 36.4 9.3 6.7 13.5 16.3 6.8 22.3 19.1 14.3 18.7 0.8 22.6 16.7 22.0 10.3 16.2 13.6 15.6 17.0 12.1 3.5 14.5 16.5 16.9 10.1 1.7 4.4 19.0 11.7 12.8 5.9 24.9 1.4 17.4 26.2 13.5 14.6 18.1 30.4 8.5 19.2 27.9 2.0 16.4 14.1 7.8 6.4 8.4 13.9 28.9 8.8 21.1 11.0 10.4 17.5 41.7 33.8 33.2 59.7 41.6 21.6 40.4 37.7 25.8 27.1 39.8 37.2 21.9 23.4 64.5 31.3 18.9 24.7 23.4 40.6 31.2 14.7 43.8 70.6 79.7 21.4 24.7 12.1 32.6 14.6 31.9 22.6 21.0 42.0 11.9 38.6 8.6 38.8 14.8 18.2 12.7 18.8 36.9 25.3 21.7 74.2 7.0 14.0 48.8 15.9 16.9 79.6 27.4 27.4 25.5 11.3 13.6 57.3 52.9 38.2 21.2 36.0 6.8 8.9 18.8 22.8 28.2 75.4 0.9 0.4 0.4 0.6 0.4 0.7 0.3 0.4 0.4 0.3 0.5 0.4 0.4 0.6 0.8 0.4 0.6 0.4 0.2 6.7 16.3 19.1 14.3 12.1 3.5 1.7 4.4 1.4 2.0 6.4 10.4 114.5 115.4 79.1 81.3 16.0 39.9 43.0 15.3 21.1 35.7 33.5 41.1 107.0 37.1 53.1 22.0 58.4 26.3 20.4 97.7 1.9 27.1 11.0 53.6 141.2 90.3 21.2 22.5 280.4 39.5 19.1 64.0 18.3 55.3 29.0 36.9 56.0 43.1 19.6 80.8 158.1 92.2 10.2 20.3 27.0 4.9 43.8 30.4 23.2 107.7 20.6 38.4 15.5 99.0 66.9 39.1 43.6 78.6 16.2 53.5 45.3 15.7 32.7 48.5 131.5 70.0 118.5 30.3 24.6 19.9 27.8 31.5 18.5 34.2 54.8 40.7 RPAP3 "FLJ21908, hSpagh, spag, Tah1" ENSG00000005175 "RNA polymerase II associated protein 3" Q9H6T3 12 47661249-47706030 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038311, HPA038312" Enhanced Enhanced Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 44: Endometrium - Transcription" Cytosol "HPA038311: AB_10671527, HPA038312: AB_10672512" "unprognostic (5.76e-2)" "unprognostic (2.25e-1)" "unprognostic (1.37e-2)" "unprognostic (4.21e-2)" "unprognostic (7.28e-2)" "unprognostic (4.47e-1)" "prognostic unfavorable (2.01e-5)" "unprognostic (9.89e-2)" "unprognostic (9.87e-3)" "unprognostic (6.34e-2)" "unprognostic (9.48e-2)" "unprognostic (1.28e-2)" "unprognostic (2.01e-2)" "unprognostic (8.35e-2)" "unprognostic (5.11e-1)" "unprognostic (3.29e-1)" "unprognostic (1.35e-2)" 10.0 10.6 6.1 19.1 6.0 12.7 15.8 8.4 7.1 12.7 6.5 12.5 13.8 13.9 14.6 13.6 14.6 12.1 16.2 5.7 7.6 13.0 15.4 10.2 29.6 6.2 8.6 19.4 8.5 17.3 8.2 13.1 7.8 12.9 12.8 11.1 9.7 12.5 22.8 11.2 12.6 15.4 6.4 17.4 11.0 15.8 7.9 23.5 13.8 23.7 29.2 16.9 9.2 7.8 42.6 39.1 46.5 32.1 24.5 34.7 39.2 41.4 42.5 51.4 43.8 54.5 47.2 93.9 55.6 37.0 37.0 41.5 40.7 24.6 59.5 50.2 38.0 63.3 25.1 26.6 21.1 68.0 42.4 17.1 29.6 60.2 21.7 41.7 32.6 36.2 70.6 28.0 45.9 30.5 58.7 48.9 49.9 39.1 33.2 46.9 56.1 46.0 41.9 38.3 33.5 24.3 48.5 39.4 41.9 49.0 40.5 40.4 23.5 35.4 47.0 39.3 46.5 21.8 43.7 66.5 33.3 148.5 22.3 3.7 10.6 32.9 10.2 20.5 10.5 20.9 11.5 11.1 14.3 17.9 14.5 13.3 19.7 13.3 25.8 9.9 15.7 9.0 6.1 6.0 8.4 7.1 5.7 7.6 6.2 8.6 7.8 6.4 7.9 7.8 16.8 12.8 17.6 11.4 30.0 13.3 14.8 20.3 24.5 18.1 18.3 19.3 41.7 11.5 21.2 11.0 8.4 23.4 33.7 7.3 23.5 17.3 9.5 51.3 23.4 13.8 13.1 18.3 15.3 19.7 16.3 21.0 15.3 26.9 12.0 22.5 8.6 18.0 18.3 11.8 12.7 12.2 14.2 19.2 16.9 7.1 21.8 24.9 7.2 14.0 44.0 13.4 25.7 16.1 16.8 11.7 16.8 20.7 31.0 7.5 9.6 30.2 30.1 14.8 6.6 16.8 18.2 48.0 37.1 22.7 10.2 17.0 21.3 18.0 14.6 9.1 RPL23 "L23, rpL17" ENSG00000125691 "Ribosomal protein L23" P62829 17 38847860-38853764 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003373 Approved Supported Cytosol NA NA 130000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Cytosol "HPA003373: AB_1856436" "unprognostic (1.02e-2)" "unprognostic (1.15e-1)" "unprognostic (9.17e-2)" "unprognostic (5.31e-2)" "unprognostic (5.62e-2)" "unprognostic (2.48e-2)" "unprognostic (9.08e-3)" "unprognostic (9.95e-2)" "unprognostic (1.02e-1)" "unprognostic (7.07e-2)" "unprognostic (8.01e-2)" "unprognostic (1.68e-1)" "prognostic unfavorable (4.19e-5)" "unprognostic (1.18e-1)" "unprognostic (9.60e-2)" "unprognostic (6.46e-3)" "unprognostic (4.45e-1)" 2078.9 1410.2 882.7 972.2 902.3 2444.5 2530.4 888.8 1161.1 2151.7 925.6 1577.9 805.2 1497.6 1786.7 1678.9 1807.0 820.5 1232.2 860.7 927.0 1410.9 1228.9 1247.9 1934.3 926.0 901.9 3960.2 2100.0 1007.4 906.0 1087.5 937.4 1501.3 1208.1 512.2 1409.8 893.5 1901.2 2283.1 1290.8 1029.7 943.8 1607.9 1409.4 336.7 908.6 1998.6 1268.0 1617.6 2264.0 1591.5 1782.4 943.3 1912.8 1871.0 2422.1 2063.9 4227.9 5507.5 1695.5 1866.3 2802.6 2301.3 1716.5 2721.1 1652.1 4214.1 1806.8 2066.8 1701.9 3284.2 2131.0 3622.1 2803.5 1466.9 3178.0 1553.9 2573.8 3929.6 3170.2 4326.7 1561.7 5216.3 4409.6 2003.4 4154.8 4103.3 2475.7 2891.2 2507.1 2069.3 3000.0 1705.8 3818.5 4600.5 1778.3 2488.3 1131.0 2560.7 3549.4 4180.4 3262.5 2384.2 1643.0 2433.7 1001.5 1707.3 3998.7 3317.1 2828.9 5324.1 1746.6 1052.1 1617.9 1666.2 3155.0 1327.3 2217.4 3326.8 1613.0 2551.5 1388.0 568.8 1536.7 318.0 1179.7 1207.3 1463.1 2374.0 1868.0 1451.6 2065.6 2159.5 2473.1 2142.2 227.0 1404.4 1069.0 2578.5 1498.0 3233.2 882.7 902.3 888.8 1161.1 860.7 927.0 926.0 901.9 937.4 943.8 908.6 943.3 764.4 1012.8 1606.1 8.5 1481.6 2446.7 2204.6 1828.9 747.3 147.1 1240.8 1011.2 532.6 1243.9 1379.0 472.6 68.8 1809.9 1282.7 652.1 1352.0 1390.0 309.2 1084.8 2160.4 1122.6 919.7 808.5 11.3 2090.7 2633.3 985.1 306.3 1353.6 1350.3 1137.2 1572.1 1581.2 1666.5 58.9 10.9 1609.3 594.1 2477.5 2490.5 233.0 2682.2 1456.6 1108.1 11.2 2741.1 735.2 1365.6 5.0 11.5 1909.4 1437.5 1447.7 491.4 2347.2 799.6 2260.6 650.8 223.6 749.4 1743.9 1908.2 259.2 219.9 1022.2 3164.9 1904.2 1207.9 1159.8 1854.8 2378.9 RPS10 "MGC88819, S10" ENSG00000124614 "Ribosomal protein S10" P46783 6 34417454-34426069 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Squamous epithelial cells: 4571.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA047268, HPA048084" Approved Approved Cytosol NA NA 130000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Cytosol "HPA047268: AB_2680007, HPA048084: AB_2680255" "unprognostic (1.92e-1)" "unprognostic (1.54e-1)" "unprognostic (8.21e-2)" "unprognostic (1.78e-1)" "unprognostic (8.92e-3)" "unprognostic (3.79e-2)" "unprognostic (9.72e-3)" "unprognostic (1.93e-2)" "unprognostic (4.30e-3)" "unprognostic (2.04e-1)" "unprognostic (3.59e-1)" "unprognostic (3.82e-1)" "prognostic unfavorable (2.57e-6)" "unprognostic (4.98e-2)" "unprognostic (7.66e-2)" "unprognostic (1.94e-1)" "unprognostic (2.45e-1)" 1437.4 1373.5 1054.1 937.6 1054.4 2688.5 2003.3 1013.6 1284.2 1984.1 1022.8 1472.3 919.9 1332.0 1064.3 1995.2 1606.9 756.7 1024.5 1010.7 1034.1 1114.4 1161.4 1006.5 2137.6 1058.2 1024.2 2878.3 2424.5 633.4 929.2 829.4 1051.3 1432.9 916.2 273.2 1532.7 895.2 1419.3 2399.7 1342.9 909.8 1088.6 1538.6 1455.3 558.6 1091.1 1486.2 1090.6 774.4 1696.6 1470.6 1716.1 1069.7 2314.3 1481.2 1486.9 3397.3 2550.1 3757.4 2454.7 1847.4 2604.3 3061.1 2200.4 3633.8 1140.6 4393.3 1873.0 2105.8 1522.9 1688.8 2814.8 3224.9 1840.0 1869.0 5082.5 1974.1 1475.4 3504.8 3492.4 3158.5 2028.2 4156.0 5548.7 2111.2 3977.8 2642.2 2725.4 2459.5 3452.0 2175.2 2327.1 3633.7 2591.3 4761.0 2242.3 5664.1 2144.7 2409.8 1736.7 4221.2 2314.1 2558.9 2492.6 1515.7 1328.4 2213.1 5332.3 1391.5 2878.1 7936.5 1837.0 1338.8 1699.0 1543.5 3072.5 1764.4 4423.0 3815.8 732.4 4092.2 2465.9 746.2 1242.2 378.2 1406.3 996.8 2067.1 2824.8 2408.2 1994.5 1679.6 2732.8 3083.6 2462.3 251.9 1676.0 963.1 1983.5 1767.5 5386.9 1054.1 1054.4 1013.6 1284.2 1010.7 1034.1 1058.2 1024.2 1051.3 1088.6 1091.1 1069.7 597.4 359.0 714.8 0.0 2967.8 1351.9 563.2 354.6 3754.5 62.0 1279.7 1271.1 65.3 1096.6 494.1 263.0 29.2 1497.5 1221.5 911.7 598.7 1451.9 447.1 169.2 282.1 670.4 1232.9 1778.0 0.0 2404.1 1918.4 612.0 1241.6 181.4 589.1 215.5 1258.9 970.6 1034.5 52.2 0.0 2462.2 130.2 1695.5 1330.7 1537.7 849.0 1006.5 633.3 0.0 1923.1 488.6 1562.3 0.0 0.0 1813.3 1843.4 472.4 2267.5 640.3 2166.8 1066.8 284.9 103.5 263.0 652.5 649.4 268.8 270.0 4571.8 1657.0 1454.1 1851.6 284.8 2985.5 573.4 RPS10-NUDT3 ENSG00000270800 "RPS10-NUDT3 readthrough" 6 34284887-34426071 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 35.3;Alveolar cells type 2: 58.7;Club cells: 19.2;granulocytes: 10.1;Respiratory ciliated cells: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 27.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA047027, HPA047268, HPA048084, HPA055953" Uncertain Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" Cytosol "HPA047027: AB_2679907, HPA047268: AB_2680007, HPA048084: AB_2680255, HPA055953: AB_2682984" "unprognostic (1.37e-1)" "unprognostic (2.10e-1)" "unprognostic (1.85e-2)" "unprognostic (7.54e-3)" "unprognostic (1.28e-2)" "unprognostic (6.85e-2)" "unprognostic (8.95e-2)" "unprognostic (2.67e-1)" "unprognostic (5.07e-2)" "unprognostic (1.36e-1)" "unprognostic (3.63e-1)" "unprognostic (5.17e-8)" "unprognostic (5.80e-2)" "unprognostic (9.49e-2)" "unprognostic (2.23e-1)" "unprognostic (1.42e-1)" 7.7 6.6 5.9 6.3 5.2 9.5 5.5 3.3 9.0 7.2 0.0 5.0 1.4 4.1 0.1 9.6 4.3 1.5 17.0 6.0 6.3 8.6 10.2 6.3 3.2 7.1 6.7 6.3 7.7 2.0 6.1 4.5 7.3 5.7 1.3 1.4 5.6 0.6 18.6 4.9 4.4 2.9 6.8 6.8 5.1 8.9 7.3 3.8 5.8 8.6 2.3 5.8 7.2 4.8 17.6 6.0 16.0 27.3 11.6 8.0 16.2 13.0 7.0 10.3 10.3 6.7 9.2 22.9 22.2 8.7 23.4 11.5 23.7 7.1 12.5 15.1 9.9 35.1 11.3 19.4 4.2 33.2 38.4 3.2 14.9 15.2 31.6 14.2 10.1 20.7 35.9 22.7 13.2 17.8 33.9 16.4 7.9 38.5 5.8 18.7 13.5 15.0 10.5 19.1 24.6 8.7 9.6 10.0 34.1 10.1 15.1 59.6 7.9 15.3 22.9 7.0 18.2 11.3 18.3 28.8 2.1 20.2 23.7 11.2 5.9 27.3 3.2 6.8 3.3 6.0 3.7 3.6 7.5 5.9 3.6 3.4 4.3 5.0 6.9 5.3 3.7 5.4 5.9 5.2 3.3 9.0 6.0 6.3 7.1 6.7 7.3 6.8 7.3 4.8 0.0 35.3 58.7 2.6 0.0 0.8 0.1 0.0 0.0 0.0 0.4 0.3 0.0 0.0 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.2 2.1 0.0 0.0 8.3 0.4 0.1 3.8 0.0 0.3 10.1 0.1 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.5 0.0 0.0 4.1 0.0 1.0 0.0 0.0 0.0 0.5 4.8 0.0 0.0 0.0 0.0 0.2 0.0 0.1 11.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 2.3 0.0 0.0 0.2 RPS18 "D6S218E, HKE3, KE-3, KE3, S18" ENSG00000231500 "Ribosomal protein S18" P62269 6 33272075-33276511 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast myoepithelial cells: 26385.3;Suprabasal keratinocytes: 31942.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050159, HPA055007" Approved Supported Cytosol NA NA 120000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Cytosol "HPA050159: AB_2681035, HPA055007: AB_2682668" "prognostic favorable (9.81e-4)" "unprognostic (1.76e-1)" "unprognostic (2.67e-1)" "unprognostic (7.74e-2)" "unprognostic (4.00e-2)" "unprognostic (3.95e-2)" "unprognostic (1.07e-2)" "unprognostic (2.51e-2)" "unprognostic (1.05e-1)" "unprognostic (1.67e-1)" "unprognostic (4.63e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.15e-10)" "unprognostic (7.00e-2)" "unprognostic (4.00e-2)" "unprognostic (2.85e-1)" "unprognostic (9.19e-2)" 3268.2 2353.2 1862.8 2097.6 1883.3 6071.7 6110.7 1827.2 2345.5 3989.9 1782.7 3060.6 2024.5 2386.7 2877.9 4570.6 3069.7 1608.3 1778.5 1806.3 1863.3 2052.0 2248.2 2034.3 4842.9 1889.4 1840.1 6497.6 5554.4 1294.1 1412.1 1956.1 1895.2 2780.5 2977.4 697.1 3045.6 1415.3 2861.9 6539.3 2565.0 1891.5 1948.2 3087.2 2634.1 789.9 1920.2 3097.1 2084.7 2140.2 4485.9 3011.2 3685.5 1926.5 4603.2 2645.2 3377.1 8930.5 5769.4 11474.6 5486.7 4471.1 6678.3 5939.4 4461.0 6787.2 2617.5 15106.6 4694.9 4890.5 2759.3 3293.1 5472.9 7251.7 4665.1 4722.4 8590.2 5617.0 2868.6 9108.9 11226.3 9771.0 2849.3 12386.6 14318.8 4498.5 13349.4 5436.5 5770.2 4373.8 7686.7 4590.7 5362.0 7880.9 4994.9 10924.1 4652.3 5367.0 3798.3 5853.7 5446.7 10293.5 5524.1 6007.1 3902.3 5714.2 1754.6 8884.0 14781.0 2429.4 6105.7 16713.0 4642.3 2714.4 3129.5 2894.4 5978.6 5376.3 12310.7 11828.5 1512.3 10665.4 3350.2 578.7 1878.9 236.8 2362.1 1653.6 4023.7 5634.6 4545.5 3382.7 3273.4 4515.8 4968.4 4374.8 184.7 3177.0 1265.3 2962.7 3727.6 9405.4 1862.8 1883.3 1827.2 2345.5 1806.3 1863.3 1889.4 1840.1 1895.2 1948.2 1920.2 1926.5 4065.5 1480.8 2569.4 9.4 8276.1 20537.2 16151.5 18150.8 5757.2 343.9 19342.8 26385.3 596.5 4185.0 6755.1 1841.0 231.4 8761.7 5535.7 2348.6 5106.4 4750.1 1164.5 1985.2 7580.0 5826.2 3089.9 3782.1 7.5 12662.2 14558.3 4617.6 2073.4 3457.9 3051.1 5393.6 6329.9 4513.1 6281.1 159.9 8.1 7793.0 4418.8 6115.9 12428.1 3197.4 9895.8 4296.2 8448.8 13.1 6356.1 1521.4 4753.9 5.0 11.5 8283.0 5985.7 4056.9 3499.7 14221.0 5563.4 5974.5 1936.4 683.4 2005.0 7010.5 6802.2 773.3 1827.1 8678.7 31942.8 8778.2 6742.0 7987.5 9896.2 16152.8 RPS28 "eS28, S28" ENSG00000233927 "Ribosomal protein S28" P62857 19 8321158-8323340 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast myoepithelial cells: 19765.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047132 Approved Approved Cytosol NA NA 730000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 32: Non-specific - Translation" Cytosol "HPA047132: AB_10962147" "unprognostic (3.47e-2)" "unprognostic (7.47e-3)" "unprognostic (1.49e-1)" "prognostic favorable (2.47e-4)" "unprognostic (3.09e-2)" "unprognostic (2.84e-3)" "unprognostic (2.16e-1)" "unprognostic (6.34e-2)" "unprognostic (1.56e-1)" "unprognostic (3.61e-2)" "unprognostic (2.80e-2)" "unprognostic (2.19e-2)" "unprognostic (3.22e-1)" "unprognostic (1.17e-1)" "unprognostic (1.40e-2)" "unprognostic (8.82e-2)" "unprognostic (1.81e-2)" 227.9 202.9 129.8 113.7 134.6 286.7 226.8 128.6 189.9 226.5 130.2 188.9 127.8 147.3 52.5 328.4 172.3 94.9 213.0 124.0 129.7 184.6 247.5 171.0 220.2 132.2 129.3 313.0 432.4 72.1 162.7 88.2 129.5 211.1 47.8 20.3 227.8 60.6 252.9 353.8 197.1 42.6 134.1 273.4 219.4 55.7 138.6 117.3 177.4 80.8 98.0 176.7 240.0 131.6 245.9 97.7 86.6 197.5 122.3 183.2 136.6 156.9 141.7 177.6 144.5 133.2 104.7 364.4 189.3 91.7 75.9 183.0 114.9 269.0 25.6 223.2 772.6 176.4 110.4 134.5 219.6 204.6 188.5 294.9 303.7 129.7 116.4 110.9 165.2 279.0 251.6 402.9 80.2 152.5 314.8 725.0 260.8 141.4 587.2 222.7 92.9 390.9 118.6 115.5 165.7 162.3 112.7 206.7 289.3 27.6 157.0 340.9 210.4 147.0 125.1 288.1 266.5 468.3 265.8 248.1 155.7 389.3 101.2 21.3 61.7 13.2 54.5 39.3 76.6 105.0 88.5 64.5 55.9 90.7 98.9 70.0 8.8 44.6 36.3 98.0 61.0 166.2 129.8 134.6 128.6 189.9 124.0 129.7 132.2 129.3 129.5 134.1 138.6 131.6 4308.7 1458.3 2798.6 9.8 6575.7 7900.9 4267.0 4952.1 5103.9 484.0 11594.7 19765.7 382.7 3044.0 2801.5 1340.8 296.1 3851.9 4608.0 2028.0 3335.8 3189.3 262.2 1687.9 4074.7 3610.1 2654.0 3550.8 7.4 7271.1 4542.0 2535.5 2746.2 2586.9 1954.3 4062.9 5016.7 5562.8 4537.9 267.5 9.3 5334.5 1287.8 5745.6 5979.8 559.6 3915.0 3716.8 3523.6 21.5 5150.0 1694.4 3560.3 6.6 14.5 5090.4 4152.6 1644.9 4225.1 3830.4 4316.3 5555.1 1153.6 729.0 1084.7 3477.1 2508.7 367.9 953.1 7848.6 10873.6 4244.9 5017.4 2121.3 5894.5 4043.4 RPS6KB2 "KLS, P70-BETA, p70S6Kb, S6Kβ, S6KB, S6Kbeta, STK14B" ENSG00000175634 "Ribosomal protein S6 kinase B2" Q9UBS0 11 67428460-67435401 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010010, CAB019404" Approved Supported Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "CAB019404: AB_331355, HPA010010: AB_1856469" "unprognostic (1.38e-1)" "unprognostic (2.36e-3)" "unprognostic (8.50e-2)" "unprognostic (2.56e-2)" "unprognostic (1.84e-1)" "unprognostic (1.41e-1)" "unprognostic (9.01e-3)" "unprognostic (5.10e-2)" "unprognostic (1.22e-1)" "unprognostic (9.49e-3)" "unprognostic (7.66e-2)" "unprognostic (2.79e-2)" "prognostic unfavorable (2.03e-7)" "unprognostic (1.28e-2)" "unprognostic (1.55e-1)" "unprognostic (2.12e-1)" "unprognostic (2.66e-1)" 16.2 28.0 9.7 13.8 10.8 28.2 17.0 9.9 12.4 23.5 13.2 22.8 26.5 17.7 6.0 71.9 20.0 10.6 22.1 9.1 9.3 21.3 50.2 19.5 18.4 10.9 10.3 16.2 35.4 17.5 20.6 13.6 10.6 31.6 12.8 4.2 31.5 9.9 37.9 81.6 25.4 10.1 10.2 33.7 35.2 9.6 9.9 24.0 20.1 26.0 20.1 19.3 31.4 11.3 58.2 42.7 22.8 39.0 10.4 20.0 30.0 27.4 33.9 49.7 34.2 67.2 37.5 21.1 46.3 26.9 31.0 41.8 25.9 41.4 19.9 36.9 70.0 34.5 54.2 55.5 35.2 43.7 40.4 25.5 42.8 26.3 26.9 12.5 37.5 54.8 55.8 54.8 25.4 88.5 68.1 68.4 24.9 83.7 54.6 50.0 31.8 100.5 23.0 32.6 34.4 37.1 28.0 76.8 59.8 13.2 90.4 35.7 15.8 25.8 27.6 63.1 31.1 48.8 43.9 34.4 42.4 27.3 33.1 18.8 37.2 28.5 23.8 42.6 24.5 23.4 22.9 23.9 44.1 21.9 16.1 17.9 24.7 29.6 49.9 30.4 34.5 37.3 9.7 10.8 9.9 12.4 9.1 9.3 10.9 10.3 10.6 10.2 9.9 11.3 22.0 9.6 20.5 6.8 48.1 49.8 28.0 48.9 19.9 25.3 32.6 27.8 1.3 28.6 31.2 7.3 10.4 71.8 45.0 66.9 43.0 44.5 14.9 16.0 16.9 17.9 46.2 65.0 7.7 64.8 89.1 21.9 48.9 19.3 27.9 23.2 18.2 57.4 61.3 33.7 7.1 67.7 34.6 45.8 29.1 29.4 20.2 36.9 19.6 3.7 56.6 28.5 73.2 5.0 12.1 46.6 70.4 17.3 82.1 43.7 115.0 42.2 16.0 27.6 19.7 16.7 26.9 15.8 16.0 52.5 63.6 103.6 41.7 27.5 58.3 39.4 RRM1 ENSG00000167325 "Ribonucleotide reductase catalytic subunit M1" P23921 11 4094707-4138932 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA replication" "Allosteric enzyme, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 102.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022093, HPA057265, HPA064297" Enhanced Supported Cytosol NA Yes 140000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "CAB022093: , HPA057265: AB_2683386, HPA064297: AB_2685236" "unprognostic (4.47e-2)" "unprognostic (1.73e-2)" "unprognostic (1.99e-3)" "unprognostic (3.65e-1)" "unprognostic (2.83e-1)" "unprognostic (2.19e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (1.31e-2)" "unprognostic (3.43e-2)" "unprognostic (6.90e-2)" "unprognostic (1.06e-3)" "unprognostic (4.21e-2)" "unprognostic (6.88e-3)" "unprognostic (9.20e-3)" "unprognostic (6.16e-2)" "unprognostic (8.41e-2)" "unprognostic (9.93e-3)" 16.6 21.2 5.1 24.8 5.3 32.8 22.7 7.1 6.1 16.9 4.7 25.7 19.3 16.2 10.1 26.5 15.5 11.8 16.4 5.1 5.7 13.4 18.4 12.8 34.4 6.1 5.5 16.4 14.6 24.7 7.1 20.4 6.6 18.5 29.4 23.6 14.7 16.0 30.3 36.1 20.2 20.1 6.2 13.0 17.6 17.9 5.1 56.7 15.6 30.0 45.2 15.6 18.9 6.2 221.6 117.8 188.4 110.0 28.4 56.2 73.0 198.0 98.2 220.7 225.9 106.8 163.8 237.4 47.0 100.1 95.9 173.0 176.9 143.2 259.3 117.3 187.9 121.0 159.8 83.1 11.2 208.9 84.6 26.6 37.8 121.7 86.4 48.3 107.8 140.1 161.1 107.3 186.8 99.6 246.7 41.9 118.2 152.2 119.2 196.1 147.0 84.3 59.4 61.8 159.8 88.1 175.1 104.8 30.0 75.8 102.8 71.4 62.3 203.4 106.0 206.9 147.4 70.3 103.5 252.5 114.1 137.6 130.3 8.3 4.0 4.5 11.3 11.2 21.1 9.2 22.3 16.6 7.3 5.2 17.2 15.0 0.0 10.5 15.6 4.4 41.7 10.3 5.1 5.3 7.1 6.1 5.1 5.7 6.1 5.5 6.6 6.2 5.1 6.2 12.4 19.2 14.4 4.9 17.0 33.4 26.8 31.0 17.6 15.6 15.1 14.4 33.5 14.3 24.7 18.4 6.2 62.8 14.9 13.3 7.9 25.6 69.9 11.5 14.5 15.7 18.0 81.2 11.2 22.2 62.5 22.0 20.4 13.9 7.0 27.3 10.8 15.0 28.3 18.5 12.0 25.0 16.2 11.7 10.3 83.9 13.1 13.9 10.6 6.5 10.7 24.0 5.2 12.1 11.9 15.8 10.4 16.6 31.3 10.1 12.5 8.4 15.5 22.7 13.1 19.5 27.1 102.8 63.1 36.5 29.0 39.7 23.2 18.1 34.3 20.6 RRM2 "C2orf48, FLJ25102" ENSG00000171848 "Ribonucleotide reductase regulatory subunit M2" P31350 2 10120698-10211725 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "DNA replication" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 44.2;esophagus: 18.4;intestine: 19.7;lymphoid tissue: 58.1" "Group enriched" "Detected in many" 4 "Erythroid cells: 214.0;Extravillous trophoblasts: 254.1;Plasma cells: 248.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056994 Enhanced Supported Cytosol Yes Yes 13000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA056994: AB_2683304" "unprognostic (2.10e-2)" "unprognostic (1.62e-1)" "unprognostic (6.40e-3)" "unprognostic (4.42e-3)" "unprognostic (5.70e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (1.39e-5)" "unprognostic (1.04e-3)" "unprognostic (6.67e-3)" "unprognostic (4.53e-2)" "prognostic unfavorable (1.62e-4)" "unprognostic (5.11e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.05e-2)" "unprognostic (2.24e-1)" "unprognostic (1.38e-1)" "unprognostic (2.09e-2)" 1.5 1.3 0.3 12.4 0.3 44.2 2.9 0.5 0.4 3.0 1.9 14.2 9.4 2.2 0.7 18.4 0.8 1.1 0.5 0.3 0.3 0.9 3.2 2.4 35.5 0.4 0.4 0.3 1.1 0.3 0.2 4.6 0.4 0.9 19.7 0.2 2.1 0.5 0.1 3.7 7.5 6.1 0.3 11.1 6.0 2.9 0.8 58.1 0.9 0.1 37.6 6.0 4.6 0.5 110.2 25.0 127.1 49.9 7.4 22.5 116.8 209.2 128.6 170.2 187.9 70.8 59.1 114.4 9.5 88.6 151.1 55.0 188.0 136.6 198.0 210.7 41.8 146.3 52.1 105.1 0.8 146.7 87.4 8.1 3.4 234.6 16.2 27.7 103.3 110.4 63.4 328.6 214.3 57.1 167.3 90.9 83.0 133.3 103.6 87.6 187.0 67.8 87.1 62.7 67.7 56.2 198.0 116.6 17.3 51.8 69.2 31.4 57.6 93.1 125.1 66.9 289.6 212.1 184.9 195.9 51.0 134.4 107.7 0.3 0.1 0.1 1.2 0.0 0.0 0.1 0.3 0.8 0.1 0.1 0.1 0.4 0.4 0.8 0.0 0.1 0.2 0.2 0.3 0.3 0.5 0.4 0.3 0.3 0.4 0.4 0.4 0.3 0.8 0.5 0.2 3.2 1.5 0.0 25.0 10.5 3.0 9.2 1.2 0.0 3.9 4.4 1.4 1.5 2.3 0.0 0.0 42.3 5.6 12.9 1.9 1.2 3.9 2.2 3.5 4.2 0.0 214.0 0.1 0.0 254.1 11.2 11.7 3.6 5.7 12.2 3.9 3.7 47.9 0.0 0.0 26.9 2.0 7.2 8.8 6.8 0.3 5.0 0.0 1.0 0.0 0.0 7.2 0.0 0.0 0.5 0.3 0.4 248.0 1.5 2.4 2.1 4.6 0.0 0.0 0.2 14.6 22.9 34.0 51.5 1.6 48.7 11.9 1.2 36.7 5.6 RTL1 "HUR1, Mar1, MART1, PEG11, SIRH2" ENSG00000254656 "Retrotransposon Gag like 1" A6NKG5 14 100879753-100903722 "Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 1.6;brain: 7.7;placenta: 2.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "melanoma: 1.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 30 "SH-SY5Y: 572.5" "Low region specificity" "Detected in many" "HPA066979, HPA077601" Enhanced Approved Cytosol No NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" Cytosol "HPA066979: AB_2685759, HPA077601: " "unprognostic (1.61e-1)" "unprognostic (3.30e-1)" "unprognostic (1.26e-1)" "unprognostic (1.42e-3)" "unprognostic (2.10e-1)" 0.1 1.6 1.6 0.0 0.7 0.0 0.0 0.9 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 7.7 0.0 0.0 0.0 0.0 3.4 4.2 0.6 0.1 0.0 0.2 2.9 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 18.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 572.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.7 0.9 1.3 1.2 7.7 3.4 4.2 7.7 0.2 4.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 RUBCNL "C13orf18, FLJ21562, KIAA0226L, PACER" ENSG00000102445 "Rubicon like autophagy enhancer" Q9H714 13 46334681-46438190 "Predicted intracellular proteins" "Autophagy, Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 41.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 6.1;B-cells: 20.7;Endometrial stromal cells: 6.7;Hofbauer cells: 16.7;Macrophages: 5.2" "Cancer enriched" "Detected in many" 5 "colorectal cancer: 17.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "memory B-cell: 161.2;naive B-cell: 155.8;neutrophil: 124.0;plasmacytoid DC: 106.2" "Group enriched" "Detected in many" 15 "B-cells: 161.2;dendritic cells: 106.2;granulocytes: 124.0" "Group enriched" "Detected in some" 4 "Daudi: 179.1;U-698: 341.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA026614 Approved Approved Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Cytosol "HPA026614: AB_10602693" "unprognostic (3.35e-2)" "unprognostic (2.61e-1)" "unprognostic (1.94e-3)" "prognostic favorable (3.76e-5)" "unprognostic (1.09e-2)" "unprognostic (8.30e-4)" "unprognostic (7.83e-2)" "unprognostic (2.62e-3)" "unprognostic (1.07e-1)" "unprognostic (1.95e-1)" "unprognostic (1.70e-1)" "unprognostic (2.28e-1)" "unprognostic (5.95e-5)" "unprognostic (1.05e-1)" "unprognostic (1.09e-1)" "unprognostic (7.47e-2)" "unprognostic (7.00e-3)" 4.2 1.3 3.7 18.0 3.8 14.8 4.0 3.5 4.1 6.6 2.5 11.9 3.0 3.7 1.2 1.0 3.7 4.0 1.0 3.4 6.8 1.1 2.2 5.2 41.2 6.2 4.8 0.6 0.7 0.3 2.0 4.2 6.1 1.5 16.2 3.9 3.0 2.6 10.1 2.0 13.2 3.6 4.9 20.3 2.2 15.7 6.3 22.9 1.9 1.4 40.6 7.5 1.3 5.9 0.5 0.1 3.6 0.2 0.1 0.2 0.3 0.0 0.2 0.2 0.1 7.5 0.2 179.1 1.8 0.0 0.9 0.2 0.1 0.0 0.1 0.7 0.3 0.2 0.2 0.1 0.0 0.2 0.2 4.7 0.0 0.6 0.9 0.0 0.0 8.2 0.3 0.4 0.0 0.1 1.9 1.4 1.5 0.0 1.4 62.6 0.1 6.1 0.0 0.1 3.4 0.1 0.2 0.3 4.4 10.8 0.2 53.0 0.1 0.2 1.6 0.3 0.4 0.9 37.3 341.2 1.1 0.3 0.2 0.5 4.5 0.1 0.1 8.9 0.1 161.2 0.3 0.1 5.1 155.8 0.1 0.1 124.0 3.5 7.1 106.2 0.2 7.5 3.7 3.8 3.5 4.1 3.4 6.8 6.2 4.8 6.1 4.9 6.3 5.9 0.2 3.2 6.1 0.0 20.7 0.0 0.0 0.0 0.0 0.0 2.9 3.9 0.0 0.0 2.5 0.0 0.0 0.3 0.3 0.0 0.0 1.4 0.0 1.3 6.7 0.4 0.0 0.0 0.0 1.2 0.4 1.1 0.0 2.5 2.5 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.6 0.2 0.0 0.0 RUFY3 "KIAA0871, RIPx, Singar1, ZFYVE30" ENSG00000018189 "RUN and FYVE domain containing 3" Q7L099 4 70704204-70808619 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 120.3" "Cell type enhanced" "Detected in all" "Astrocytes: 189.4;Cone photoreceptor cells: 264.8;Excitatory neurons: 192.9;Oligodendrocytes: 197.8;Rod photoreceptor cells: 198.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022952, HPA022970" Enhanced Supported Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 77: Retina - Visual perception" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "HPA022952: AB_2671005, HPA022970: AB_1856307" "unprognostic (4.33e-2)" "unprognostic (1.60e-2)" "unprognostic (1.30e-1)" "unprognostic (3.96e-3)" "unprognostic (1.38e-1)" "prognostic favorable (1.28e-4)" "prognostic unfavorable (8.95e-4)" "unprognostic (1.69e-2)" "unprognostic (2.00e-1)" "unprognostic (3.50e-2)" "prognostic favorable (8.02e-5)" "unprognostic (7.90e-3)" "unprognostic (1.31e-3)" "unprognostic (1.26e-1)" "unprognostic (1.21e-2)" "unprognostic (7.45e-3)" "unprognostic (5.41e-1)" 19.4 34.8 57.1 18.2 63.7 11.6 18.7 63.3 77.0 28.6 27.6 18.9 12.0 29.4 23.3 24.4 18.0 17.7 16.0 63.8 72.0 22.1 22.2 21.9 21.7 77.1 63.0 35.8 19.2 8.2 41.1 17.5 81.5 19.2 16.0 120.3 18.9 15.6 25.6 46.5 15.0 20.8 61.4 25.4 19.1 39.0 63.6 32.5 45.7 11.7 17.3 19.9 25.7 99.3 8.5 5.8 67.0 15.9 30.8 35.2 26.6 26.6 10.2 8.5 9.4 9.9 20.2 33.2 10.8 22.4 19.1 8.4 10.3 11.8 13.6 18.2 13.4 7.2 8.4 11.6 18.0 8.4 4.3 24.7 18.0 11.4 13.3 39.5 18.3 35.4 20.2 32.9 18.8 10.4 52.8 9.6 16.1 14.7 7.3 12.8 21.0 15.2 16.7 8.0 61.7 30.6 9.7 17.0 16.2 25.8 11.7 4.2 15.7 28.8 20.0 8.8 6.2 37.2 18.0 35.7 29.4 6.1 6.0 0.6 3.4 0.3 1.5 4.8 1.9 3.5 1.2 1.3 4.9 2.6 1.2 1.3 0.1 2.6 4.9 6.6 0.5 0.8 57.1 63.7 63.3 77.0 63.8 72.0 77.1 63.0 81.5 61.4 63.6 99.3 31.9 35.3 82.1 189.4 18.7 19.4 23.3 9.9 15.9 126.9 22.1 11.8 19.3 12.8 30.6 23.9 264.8 15.0 19.5 7.5 7.9 14.7 70.0 32.9 63.6 32.6 15.0 7.4 192.9 21.1 7.0 43.7 23.4 36.0 21.0 53.1 32.9 25.7 10.5 139.7 175.0 8.4 14.2 37.3 36.4 122.5 47.2 31.0 42.7 72.1 67.0 43.9 13.4 136.7 197.8 19.1 5.2 50.8 17.2 40.2 11.6 19.6 28.3 198.6 26.3 53.2 35.9 14.8 27.6 36.7 28.8 7.7 11.5 40.9 10.1 19.3 RUSC1 NESCA ENSG00000160753 "RUN and SH3 domain containing 1" Q9BVN2 1 155320894-155331114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 82.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028510, HPA029922, HPA029923" Approved Enhanced Cytosol NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA028510: AB_10599847, HPA029922: AB_10611390, HPA029923: AB_10602288" "unprognostic (1.98e-1)" "unprognostic (2.82e-1)" "unprognostic (2.36e-1)" "unprognostic (1.50e-1)" "unprognostic (5.25e-2)" "unprognostic (2.52e-1)" "prognostic unfavorable (7.78e-6)" "unprognostic (1.42e-1)" "unprognostic (1.38e-1)" "unprognostic (1.73e-1)" "unprognostic (8.29e-2)" "prognostic unfavorable (2.65e-4)" "prognostic unfavorable (9.24e-6)" "unprognostic (7.59e-2)" "unprognostic (4.25e-2)" "unprognostic (2.05e-2)" "unprognostic (1.40e-1)" 27.0 26.6 42.0 11.6 40.7 12.8 23.2 39.9 66.0 38.0 11.3 39.2 21.6 28.8 8.7 49.5 24.8 16.8 28.8 38.9 41.1 32.1 12.6 23.7 10.7 55.2 34.0 27.5 22.5 11.7 45.0 18.2 53.2 32.1 22.9 11.9 32.0 20.3 14.1 37.3 29.9 18.6 28.3 18.0 27.3 6.6 41.4 18.6 19.3 13.3 11.3 26.6 39.2 41.0 70.4 43.5 24.5 36.4 29.6 32.1 47.2 32.7 20.8 42.2 47.1 50.1 45.2 13.7 24.4 33.2 24.2 95.1 38.3 47.4 18.2 18.8 48.8 19.8 44.7 26.6 24.5 19.9 32.9 33.0 29.3 42.5 14.6 20.4 43.9 29.7 30.5 9.4 36.9 133.4 25.0 25.3 48.4 128.4 68.3 33.6 17.1 24.3 40.3 52.7 25.2 40.5 27.6 76.9 16.8 39.8 114.8 33.6 20.2 54.0 44.4 51.4 65.8 7.4 18.0 8.6 38.2 26.5 15.0 5.8 8.0 4.0 6.3 9.8 7.2 3.6 5.1 6.4 8.8 1.5 2.8 6.0 1.1 3.3 25.2 8.4 5.5 5.4 42.0 40.7 39.9 66.0 38.9 41.1 55.2 34.0 53.2 28.3 41.4 41.0 18.2 9.6 12.7 4.9 8.0 28.0 20.1 29.5 22.8 16.9 21.3 19.3 10.2 15.7 27.9 18.4 6.2 30.8 14.8 82.2 23.5 22.4 0.4 9.9 14.7 20.0 15.6 14.5 23.8 17.7 76.6 19.1 25.5 23.6 8.2 9.8 16.4 7.8 21.0 37.0 30.5 51.7 18.3 12.8 20.3 0.5 18.3 11.9 19.6 6.5 11.7 13.4 15.5 7.1 8.2 25.6 43.7 18.0 8.4 29.4 51.8 27.9 10.4 7.0 19.7 12.7 22.2 2.3 8.9 41.4 34.9 38.0 15.2 6.7 40.1 26.0 S100A7 "PSOR1, S100A7c" ENSG00000143556 "S100 calcium binding protein A7" P31151 1 153457744-153460651 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 1065.7;lymphoid tissue: 1239.6;skin 1: 346.5;vagina: 1020.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 59.3;Club cells: 70.4;Ionocytes: 18.3;Suprabasal keratinocytes: 89.6;Syncytiotrophoblasts: 26.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 1201.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HaCaT: 7.2;SK-BR-3: 16.9" "CAB001453, HPA006997, CAB033766" Enhanced Uncertain Cytosol "Secreted in other tissues" NA NA 14000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "CAB001453: AB_564004, CAB033766: AB_2269963, HPA006997: AB_1079860" "unprognostic (3.28e-1)" "unprognostic (9.85e-2)" "unprognostic (1.32e-2)" "unprognostic (2.16e-2)" "unprognostic (3.17e-1)" "unprognostic (2.94e-2)" "unprognostic (1.03e-2)" "unprognostic (4.00e-1)" "unprognostic (1.25e-1)" "unprognostic (1.27e-1)" "unprognostic (2.99e-1)" "unprognostic (5.41e-2)" "unprognostic (1.21e-2)" 1.0 0.2 0.9 0.0 0.8 0.8 15.6 1.4 2.1 174.8 0.7 0.3 0.0 1.2 27.6 1065.7 0.3 0.2 0.5 0.8 0.8 0.1 0.5 0.4 0.2 0.9 0.8 0.5 0.4 0.0 0.2 0.2 0.8 0.5 0.0 0.0 55.5 0.2 0.4 346.5 0.2 1.4 0.8 0.3 0.4 0.3 0.7 12.4 0.2 0.0 1239.6 1.2 1020.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 7.2 0.0 2.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.4 0.0 0.0 2.0 0.0 0.0 0.2 0.0 0.0 2.0 0.0 0.0 0.4 0.0 0.2 0.0 0.2 0.0 0.0 0.7 0.1 0.4 0.0 0.0 0.0 0.7 16.9 0.0 0.9 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.8 1.4 2.1 0.8 0.8 0.9 0.8 0.8 0.8 0.7 1.1 0.0 0.0 0.0 0.0 0.0 11.7 0.2 59.3 0.0 0.0 1.1 0.0 0.0 0.0 70.4 0.0 0.0 0.2 0.0 0.0 0.0 1.1 0.3 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 2.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 18.3 0.0 1.9 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 6.3 0.0 0.0 0.0 4.7 0.2 0.2 3.8 89.6 26.4 0.1 8.4 0.6 0.4 S100A7A "S100A15, S100A7f, S100A7L1" ENSG00000184330 "S100 calcium binding protein A7A" Q86SG5 1 153416520-153423222 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "esophagus: 5.6;lymphoid tissue: 5.9;skin 1: 1.6;vagina: 2.7" "Group enriched" "Detected in some" 8 "Early spermatids: 2.8;Late spermatids: 3.0;Suprabasal keratinocytes: 1.8" "Group enriched" "Detected in many" 4 "head and neck cancer: 25.6;melanoma: 12.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA006997 Supported Uncertain Cytosol NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA006997: AB_1079860" "unprognostic (2.18e-1)" "unprognostic (1.26e-1)" "unprognostic (3.73e-2)" "unprognostic (4.65e-2)" "unprognostic (1.40e-1)" "unprognostic (1.77e-1)" "unprognostic (1.17e-1)" "unprognostic (4.40e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 5.9 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.8 0.0 0.0 0.0 0.0 0.0 S100G "CABP1, CABP9K, CALB3" ENSG00000169906 "S100 calcium binding protein G" P29377 X 16650158-16654670 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 202 "intestine: 238.5" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "breast cancer: 4.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RPMI-8226: 2.5" "Region enriched" "Detected in single" 5 "pons and medulla: 1.1" "Not detected" "Not detected" "CAB017688, HPA028920, HPA055873" Enhanced Approved Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 45: Enterocytes - Digestion" Cytosol "CAB017688: AB_1119899, HPA028920: , HPA055873: AB_2682952" "unprognostic (2.68e-2)" "unprognostic (2.78e-1)" "unprognostic (9.88e-3)" 0.0 0.0 0.1 0.1 0.3 0.1 1.1 0.7 0.1 0.0 0.1 0.3 238.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 2.5 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.7 0.1 0.1 0.6 0.5 0.1 0.4 0.2 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SAC3D1 "HSU79266, SHD1" ENSG00000168061 "SAC3 domain containing 1" 11 65040901-65044828 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 94.1;Late spermatids: 121.5;Spermatocytes: 166.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042677 Uncertain Approved Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA042677: AB_10797506" "unprognostic (1.35e-1)" "unprognostic (5.45e-3)" "unprognostic (5.00e-1)" "unprognostic (8.01e-2)" "unprognostic (3.56e-1)" "unprognostic (3.53e-2)" "prognostic unfavorable (9.67e-6)" "unprognostic (4.11e-1)" "unprognostic (1.70e-1)" "unprognostic (4.45e-2)" "unprognostic (4.71e-2)" "unprognostic (3.20e-1)" "prognostic unfavorable (5.66e-5)" "unprognostic (2.97e-3)" "unprognostic (5.71e-1)" "unprognostic (4.53e-2)" "unprognostic (2.49e-1)" 3.8 3.4 9.9 2.7 9.5 4.1 2.0 9.6 10.6 3.1 7.5 3.6 3.1 3.1 0.6 3.6 2.8 0.7 2.6 9.8 9.1 2.1 3.7 2.1 2.8 11.7 9.9 2.5 2.8 1.3 2.7 1.4 10.7 2.8 1.2 0.6 2.7 2.0 9.3 3.7 2.6 2.0 9.4 3.1 2.9 13.5 10.4 7.1 1.4 2.1 2.1 2.6 2.5 10.2 48.3 27.4 13.3 15.1 6.8 5.0 18.9 28.2 6.3 15.9 13.8 13.4 11.3 20.8 22.2 7.7 17.6 32.1 14.4 15.6 2.7 33.0 44.9 15.5 24.5 42.3 5.1 14.5 11.6 3.9 13.4 12.2 5.4 4.4 5.5 20.3 25.7 16.3 6.1 32.6 39.7 75.9 12.1 13.5 61.2 38.0 19.4 31.7 6.8 10.6 29.9 19.6 21.9 22.2 19.4 3.8 20.8 15.3 6.7 13.6 36.9 37.8 20.0 35.6 30.8 22.7 8.0 15.2 4.5 0.0 1.4 0.2 0.6 1.1 0.5 0.9 0.9 0.7 0.7 1.1 1.0 0.6 0.1 0.2 1.5 1.6 0.9 0.4 9.9 9.5 9.6 10.6 9.8 9.1 11.7 9.9 10.7 9.4 10.4 10.2 7.6 3.2 0.5 3.6 7.1 8.7 5.4 2.5 15.9 6.9 19.0 22.7 5.8 11.5 1.5 9.2 0.0 21.9 11.2 26.3 7.9 3.1 94.1 6.4 13.6 6.4 7.2 16.2 4.0 1.6 42.9 10.7 8.2 7.1 5.7 28.0 5.3 17.9 30.4 5.0 4.2 18.5 0.0 15.1 5.5 121.5 17.7 10.4 10.6 1.0 10.5 13.6 13.4 2.5 5.5 2.4 15.2 13.9 11.3 11.2 14.5 14.7 1.3 9.3 0.0 8.1 10.6 166.7 42.2 20.1 7.7 6.7 11.1 22.2 27.6 3.9 SAMD4B "FLJ10211, hSmaug2, MGC99832, SMGB" ENSG00000179134 "Sterile alpha motif domain containing 4B" Q5PRF9 19 39342396-39385710 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 166.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016800, HPA059385" Approved Enhanced Cytosol No No "Cluster 46: Basophils - DNA binding" "Cluster 35: Non-specific - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "HPA016800: AB_1856552, HPA059385: AB_2684000" "unprognostic (2.56e-1)" "unprognostic (6.76e-2)" "unprognostic (2.09e-2)" "prognostic unfavorable (2.17e-6)" "unprognostic (3.41e-2)" "unprognostic (8.66e-2)" "unprognostic (6.24e-3)" "unprognostic (2.31e-2)" "unprognostic (1.15e-1)" "unprognostic (4.98e-2)" "unprognostic (2.30e-1)" "unprognostic (4.92e-2)" "unprognostic (1.34e-2)" "unprognostic (1.32e-1)" "unprognostic (9.91e-3)" "unprognostic (2.12e-1)" "unprognostic (1.89e-2)" 46.1 39.7 37.3 24.5 48.1 20.3 42.1 31.1 37.5 56.6 18.1 47.1 18.9 49.7 16.8 65.0 47.3 26.7 39.6 34.2 34.5 33.2 31.2 45.7 15.1 51.9 45.9 60.8 34.2 36.3 48.1 26.2 39.9 41.9 15.8 23.4 42.8 33.3 36.0 54.9 34.9 27.9 35.9 32.9 40.2 41.4 40.7 19.2 44.1 19.2 15.1 46.1 52.9 53.6 97.8 131.0 65.6 49.7 62.7 75.1 54.1 55.1 60.0 43.2 35.7 114.6 53.2 32.3 70.2 88.4 56.0 46.2 65.3 50.4 29.5 65.3 106.1 32.4 55.5 48.6 64.7 35.5 32.7 74.1 58.5 70.8 52.3 52.6 41.3 42.9 97.6 34.0 53.3 65.8 38.1 17.3 52.2 63.5 51.6 45.9 42.2 28.3 36.3 77.8 66.6 65.0 72.1 48.8 39.2 49.4 39.5 37.8 54.6 70.0 50.6 153.5 97.8 64.0 62.2 35.8 93.4 26.7 70.2 1.2 1.0 1.5 1.0 0.4 0.7 1.2 0.8 0.9 0.8 0.6 1.3 0.9 2.7 0.9 0.3 0.9 0.3 0.5 37.3 48.1 31.1 37.5 34.2 34.5 51.9 45.9 39.9 35.9 40.7 53.6 28.8 12.8 30.4 55.8 21.6 33.3 62.7 22.4 12.0 56.9 37.1 32.9 8.4 24.3 18.9 36.8 166.8 25.7 21.7 26.4 5.9 26.2 6.9 44.9 42.5 31.9 51.0 19.8 26.6 27.3 23.1 39.1 19.9 55.3 18.9 39.0 36.8 26.6 20.7 52.2 31.0 28.1 10.2 25.5 38.2 5.4 43.8 28.5 19.6 25.3 18.4 31.4 16.5 34.2 106.0 41.0 19.6 33.1 19.3 65.7 20.2 12.3 30.7 67.9 65.7 43.9 30.9 70.3 42.7 15.6 43.5 54.6 20.4 33.8 24.5 65.9 SAMD9L "C7orf6, FLJ39885, KIAA2005" ENSG00000177409 "Sterile alpha motif domain containing 9 like" Q8IVG5 7 93130056-93148385 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 38.3" "Cell type enhanced" "Detected in many" "monocytes: 64.8;NK-cells: 91.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 54.0;GAMG: 44.1;HDLM-2: 51.2;Karpas-707: 131.4" "Low region specificity" "Detected in all" "HPA019461, HPA019465, HPA019488" Enhanced Approved Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA019461: AB_1856555, HPA019465: AB_2183384, HPA019488: AB_1856557" "unprognostic (6.93e-3)" "unprognostic (6.12e-2)" "unprognostic (5.00e-2)" "unprognostic (2.21e-2)" "unprognostic (4.13e-2)" "unprognostic (5.03e-2)" "unprognostic (7.10e-2)" "unprognostic (4.21e-2)" "unprognostic (2.32e-1)" "unprognostic (6.18e-3)" "unprognostic (1.05e-3)" "unprognostic (2.61e-1)" "prognostic unfavorable (6.63e-5)" "unprognostic (1.36e-1)" "unprognostic (2.07e-2)" "unprognostic (1.85e-2)" "unprognostic (1.22e-1)" 10.2 6.0 4.0 24.4 4.6 10.0 7.5 3.6 4.4 7.2 3.7 10.5 11.5 7.3 4.5 6.3 6.5 13.8 6.2 3.6 4.9 6.8 6.1 21.9 27.1 9.5 4.5 9.1 3.2 1.9 3.9 12.6 5.9 4.3 11.4 2.4 12.9 4.2 2.9 4.1 11.7 9.1 8.0 38.3 14.4 2.9 5.4 22.9 6.7 4.6 16.2 11.9 6.3 6.3 7.2 0.4 0.0 0.4 9.3 18.7 0.2 6.2 25.7 34.5 54.0 0.0 15.9 4.7 7.7 16.7 44.1 3.1 0.0 2.2 5.5 51.2 0.0 4.3 1.9 0.0 7.5 9.6 7.0 7.2 0.8 6.9 1.0 6.4 15.1 7.1 0.0 131.4 14.6 0.0 15.3 8.5 0.5 0.0 1.8 6.3 2.2 11.0 1.8 0.6 0.0 0.3 1.3 0.2 9.8 0.1 0.4 5.0 35.8 10.1 2.2 29.6 3.8 36.4 13.0 1.3 10.6 8.6 10.1 30.1 6.7 16.7 13.4 13.3 11.6 15.1 7.4 10.0 6.3 10.3 4.3 7.7 29.2 8.2 12.8 4.7 11.8 4.0 4.0 4.6 3.6 4.4 3.6 4.9 9.5 4.5 5.9 8.0 5.4 6.3 37.4 35.3 11.2 15.7 28.5 2.3 2.3 6.0 4.6 0.0 8.0 5.5 1.8 2.8 9.6 11.0 0.0 0.3 34.2 18.8 9.8 12.7 0.1 4.9 16.3 28.0 1.2 10.1 0.2 5.7 1.0 14.3 20.4 2.4 34.2 12.2 27.5 0.4 24.4 0.0 0.1 12.6 6.1 20.4 12.9 1.1 9.6 36.5 7.2 44.0 64.8 14.1 91.6 0.0 0.2 16.2 50.2 11.7 28.1 3.1 5.1 4.2 18.6 0.4 6.6 15.0 7.7 0.3 0.2 4.1 2.3 0.1 34.0 12.2 4.1 8.0 SARS1 "SARS, SERS" ENSG00000031698 "Seryl-tRNA synthetase 1" P49591 1 109213918-109238182 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis, Transcription, Transcription regulation" "Aminoacyl-tRNA synthetase, DNA-binding, Ligase" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 98.8;Cytotrophoblasts: 186.0;Extravillous trophoblasts: 147.6;Hofbauer cells: 88.1;Syncytiotrophoblasts: 188.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016939, HPA064668" Approved Enhanced Cytosol NA NA 330000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA016939: AB_1856585, HPA064668: AB_2685316" "unprognostic (4.92e-2)" "unprognostic (2.61e-1)" "unprognostic (5.87e-2)" "unprognostic (6.78e-2)" "prognostic favorable (9.47e-4)" "prognostic unfavorable (5.75e-4)" "prognostic unfavorable (6.13e-5)" "unprognostic (3.02e-1)" "unprognostic (1.77e-1)" "unprognostic (2.68e-2)" "unprognostic (3.23e-1)" "unprognostic (2.06e-1)" "unprognostic (1.69e-1)" "unprognostic (1.71e-1)" "unprognostic (1.56e-1)" "unprognostic (3.85e-2)" "unprognostic (3.45e-3)" 86.9 89.4 78.6 55.9 78.6 35.7 80.5 77.2 98.1 79.3 57.4 89.1 63.6 85.8 64.2 97.1 71.5 53.6 96.0 81.9 92.6 77.4 102.4 102.3 60.9 88.3 81.1 78.5 150.1 102.1 88.6 76.2 91.1 66.2 74.8 68.0 86.1 73.9 113.3 111.9 69.9 79.3 72.9 64.5 112.4 46.3 78.1 66.7 139.8 87.9 76.4 88.3 82.1 90.9 208.5 82.1 152.3 230.3 224.2 201.4 261.6 213.1 222.1 183.7 227.1 161.4 62.7 224.1 107.7 307.2 102.8 111.6 241.1 305.9 212.4 159.0 150.4 86.6 96.3 118.4 448.1 110.5 93.7 249.4 526.5 217.1 467.7 155.9 221.9 279.5 201.9 273.2 181.3 205.8 124.8 57.5 63.4 125.6 193.5 101.1 192.5 102.6 139.9 111.0 210.0 111.2 102.5 164.7 601.4 114.9 93.5 131.2 174.5 108.3 135.0 155.5 151.8 205.6 89.6 183.7 341.3 119.8 376.7 191.5 193.9 219.6 228.6 212.2 240.0 235.8 238.2 227.3 198.8 252.4 246.4 229.4 89.7 193.5 226.6 128.2 300.9 460.5 78.6 78.6 77.2 98.1 81.9 92.6 88.3 81.1 91.1 72.9 78.1 90.9 30.6 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 98.8 0.0 0.0 0.0 0.0 186.0 28.8 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.0 147.6 23.9 0.0 0.0 0.0 0.0 0.0 0.0 88.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 188.4 5.9 0.0 0.0 0.0 SAV1 "salvador, WW45, WWP4" ENSG00000151748 "Salvador family WW domain containing protein 1" Q9H4B6 14 50632058-50668306 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001808 Approved Supported Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA001808: AB_2666441" "prognostic favorable (2.92e-5)" "unprognostic (5.17e-2)" "unprognostic (1.24e-1)" "unprognostic (1.52e-2)" "unprognostic (4.38e-1)" "unprognostic (1.42e-1)" "unprognostic (1.44e-3)" "unprognostic (3.00e-2)" "unprognostic (1.82e-1)" "unprognostic (1.37e-1)" "unprognostic (1.41e-3)" "unprognostic (5.20e-2)" "prognostic favorable (3.83e-6)" "unprognostic (2.32e-1)" "unprognostic (2.05e-1)" "unprognostic (1.28e-2)" "unprognostic (1.90e-3)" 32.2 16.4 14.0 12.8 16.7 7.3 35.3 15.1 16.9 24.5 22.0 17.0 15.3 23.3 18.8 15.8 21.2 26.2 24.2 12.8 15.0 22.9 17.6 20.2 15.7 16.5 15.1 37.7 34.4 27.0 8.5 17.0 16.1 27.6 12.6 17.6 45.5 19.2 23.1 17.8 13.2 17.7 14.7 18.6 18.9 30.6 16.6 10.3 34.2 27.1 14.7 16.7 18.7 19.6 96.3 10.7 17.8 12.4 43.5 39.8 22.4 26.6 87.3 34.1 43.4 16.0 47.8 14.9 63.9 26.4 17.8 42.8 25.7 28.9 62.9 45.6 20.8 16.4 16.4 11.4 21.3 17.9 14.0 24.9 36.5 15.3 33.8 25.8 24.5 15.9 27.5 7.2 42.5 17.9 15.1 11.0 33.1 21.6 17.3 17.2 49.5 6.1 21.5 13.6 22.2 16.8 47.1 27.7 41.3 28.9 20.3 18.0 17.7 16.2 55.5 22.4 16.4 11.3 15.4 9.0 11.1 7.2 22.1 0.6 0.3 0.0 0.9 0.3 0.9 3.3 0.7 0.5 0.3 3.4 0.5 0.7 0.5 0.5 0.4 1.2 1.0 0.4 14.0 16.7 15.1 16.9 12.8 15.0 16.5 15.1 16.1 14.7 16.6 19.6 76.4 35.3 44.0 9.4 35.8 65.9 37.2 19.1 24.5 19.6 76.4 60.6 39.1 15.7 35.1 18.4 25.0 19.9 14.7 11.2 17.6 40.5 92.5 39.6 47.3 76.9 5.4 27.0 10.4 47.6 23.0 59.3 11.7 58.1 2.5 46.4 59.3 14.5 10.5 5.0 10.0 10.1 10.2 13.5 61.5 26.1 66.8 34.1 30.2 12.2 11.6 26.9 2.1 12.5 27.0 66.5 14.6 42.5 7.4 81.4 12.1 16.3 33.3 26.4 6.6 41.8 45.1 41.4 38.8 14.6 59.5 23.1 9.4 17.7 9.6 34.1 SCARB2 "CD36L2, HLGP85, LIMP-2, LIMPII, SR-BII" ENSG00000138760 "Scavenger receptor class B member 2" Q14108 4 76158737-76234536 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 12.5;classical monocyte: 14.1;intermediate monocyte: 26.0;myeloid DC: 8.2;non-classical monocyte: 24.9;plasmacytoid DC: 28.9" "Group enriched" "Detected in all" 5 "dendritic cells: 28.9;granulocytes: 12.5;monocytes: 26.0" "Cell line enhanced" "Detected in many" "ASC diff: 499.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015415, HPA018014" Supported Approved Cytosol NA NA 9200 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 35: Glandular cells - Unknown function" Cytosol "CAB015415: AB_831511, HPA018014: AB_1852881" "prognostic unfavorable (2.82e-5)" "unprognostic (2.73e-2)" "unprognostic (4.09e-2)" "unprognostic (4.96e-2)" "unprognostic (4.17e-3)" "unprognostic (1.12e-3)" "unprognostic (2.08e-1)" "unprognostic (5.48e-2)" "unprognostic (4.06e-1)" "unprognostic (1.25e-2)" "unprognostic (4.11e-2)" "unprognostic (1.67e-1)" "unprognostic (1.91e-2)" "unprognostic (1.17e-1)" "unprognostic (6.88e-2)" "unprognostic (5.06e-2)" "unprognostic (3.89e-2)" 60.6 24.0 33.5 27.7 63.5 7.3 56.7 58.9 38.9 60.8 18.9 61.6 39.2 44.1 58.4 33.9 45.4 60.0 61.6 29.6 48.6 46.8 89.9 77.1 20.2 62.2 49.6 58.9 58.9 63.6 11.1 80.2 62.5 72.3 64.0 53.2 80.5 55.4 89.8 26.0 49.1 57.8 60.1 47.0 60.7 19.4 50.7 21.3 65.9 81.3 20.6 65.3 25.1 92.9 39.8 38.4 48.9 97.1 499.7 242.0 35.8 131.5 250.2 114.0 178.2 72.5 112.3 0.0 85.1 262.3 109.6 28.3 28.3 78.9 96.0 138.8 30.1 3.2 32.9 25.3 129.9 19.0 12.1 186.9 72.3 117.3 54.5 268.9 200.6 10.0 15.6 188.6 159.2 58.2 1.6 4.0 9.7 120.3 23.6 23.3 82.7 42.0 64.4 43.6 101.3 110.2 104.7 61.3 115.5 49.3 34.6 17.1 131.3 125.9 48.5 104.7 47.5 167.6 98.8 0.2 158.1 22.2 170.9 12.5 14.1 3.1 2.8 26.0 2.6 3.8 1.9 1.5 8.2 3.0 2.6 4.3 1.9 1.1 24.9 28.9 3.0 6.1 33.5 63.5 58.9 38.9 29.6 48.6 62.2 49.6 62.5 60.1 50.7 92.9 89.0 176.3 52.4 47.3 20.1 24.0 90.5 64.8 34.1 109.6 69.7 36.4 53.0 87.2 52.1 99.3 60.5 35.3 43.6 109.0 7.9 119.9 7.1 50.3 74.0 69.9 102.4 28.6 57.4 72.9 47.5 108.3 40.8 88.8 3.8 84.8 79.6 108.7 143.4 60.6 55.4 77.1 44.7 165.7 27.5 5.6 45.4 76.2 67.6 38.4 43.5 87.2 6.2 106.1 201.1 78.0 68.3 66.5 82.2 133.5 103.2 27.6 54.4 81.7 92.1 91.0 68.1 18.2 16.5 34.8 33.8 59.4 16.3 56.5 55.3 93.4 SCGN "CALBL, DJ501N12.8, SECRET, SEGN" ENSG00000079689 "Secretagogin, EF-hand calcium binding protein" O76038 6 25652201-25701783 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 43.5;pancreas: 67.1;pituitary gland: 38.5" "Cell type enriched" "Detected in some" 5 "Enteroendocrine cells: 600.1" "Cancer enhanced" "Detected in many" "pancreatic cancer: 38.2;renal cancer: 22.6" "Group enriched" "Detected in many" 4 "cerebellum: 23.6;hippocampal formation: 14.5;hypothalamus: 43.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 3.4;CACO-2: 6.4;HEL: 4.6;Hep G2: 3.6;SCLC-21H: 24.7" "Region enriched" "Detected in many" 16 "olfactory bulb: 82.0" "Region enriched" "Detected in some" 9 "olfactory bulb: 137.1" "CAB004005, HPA006641, CAB044060, CAB062563, CAB068232" Enhanced Supported Supported Cytosol "Intracellular and membrane" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Cytosol "CAB004005: , CAB044060: , CAB062563: AB_2665612, CAB068232: AB_2665613, HPA006641: AB_1079874" "unprognostic (8.15e-2)" "unprognostic (4.31e-3)" "unprognostic (1.46e-1)" "unprognostic (1.25e-2)" "unprognostic (4.70e-1)" "unprognostic (1.78e-2)" "unprognostic (2.01e-1)" "unprognostic (5.14e-2)" "unprognostic (5.41e-2)" "unprognostic (9.45e-2)" "unprognostic (1.19e-1)" 3.7 3.5 1.7 3.4 1.2 0.2 3.3 23.6 2.9 0.1 0.1 16.9 12.4 0.0 0.0 0.2 0.1 0.9 11.7 14.5 43.5 1.4 4.1 0.8 0.1 1.7 2.3 0.3 67.1 0.1 38.5 3.3 6.1 2.0 19.2 1.0 2.5 0.1 0.0 0.6 11.5 1.2 1.4 0.0 18.9 0.6 0.9 0.4 1.9 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 4.6 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 24.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.2 23.6 2.9 14.5 43.5 1.7 2.3 6.1 1.4 0.9 0.5 1.9 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 1.0 0.6 0.5 107.2 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.1 0.0 0.0 2.2 600.1 0.0 0.2 0.4 0.2 0.3 9.2 0.0 0.0 0.9 3.3 0.5 0.1 0.0 1.8 14.3 4.1 0.0 0.0 0.2 0.6 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.1 4.8 3.7 0.0 0.0 3.7 1.1 3.1 0.0 0.0 13.1 0.0 9.1 0.2 1.1 0.0 0.0 0.0 0.1 0.5 2.2 0.3 SCRN1 KIAA0193 ENSG00000136193 "Secernin 1" Q12765 7 29920104-29990289 "Enzymes, Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 159.0" "Cell type enhanced" "Detected in many" "Muller glia cells: 80.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "WM-115: 326.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024517 Enhanced Approved Cytosol No No 160000 "Cluster 51: Monocytes - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" Cytosol "HPA024517: AB_2184811" "prognostic unfavorable (8.32e-4)" "prognostic unfavorable (8.46e-4)" "unprognostic (1.45e-1)" "prognostic unfavorable (4.00e-5)" "unprognostic (1.87e-2)" "unprognostic (2.43e-1)" "unprognostic (1.13e-3)" "unprognostic (1.10e-1)" "unprognostic (2.29e-1)" "prognostic unfavorable (7.27e-4)" "unprognostic (1.09e-2)" "unprognostic (1.02e-1)" "prognostic favorable (1.15e-5)" "unprognostic (2.57e-2)" "unprognostic (2.10e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (2.60e-4)" 13.9 27.9 112.4 13.1 118.9 8.1 14.3 128.2 117.9 22.2 52.2 27.5 6.5 27.4 16.2 19.0 26.0 16.5 19.8 112.5 129.0 23.7 2.6 16.4 14.3 112.5 159.0 32.4 36.7 54.5 34.0 15.8 115.5 27.9 10.4 102.5 18.0 37.2 2.4 11.1 15.8 34.3 116.1 10.8 19.3 23.0 122.5 28.9 13.5 11.0 21.6 22.0 17.8 127.1 106.3 75.0 119.9 48.6 83.1 126.9 0.5 97.0 128.8 102.5 110.0 87.1 81.8 13.0 83.7 124.7 227.3 46.7 137.7 41.2 148.9 0.6 29.0 43.8 49.7 56.6 105.9 0.3 0.5 106.5 58.1 93.5 49.6 139.4 95.9 28.0 0.5 33.3 146.6 59.5 15.5 0.1 109.4 0.2 79.6 0.3 127.7 1.1 71.7 51.5 43.7 103.1 99.9 64.1 112.5 149.7 86.3 6.9 106.7 132.2 113.3 1.7 123.7 10.8 177.0 1.1 62.4 0.5 326.5 3.7 3.4 10.3 0.9 14.1 10.7 14.0 0.2 1.0 10.9 7.6 0.7 1.4 0.5 7.1 25.4 10.8 0.0 3.5 112.4 118.9 128.2 117.9 112.5 129.0 112.5 159.0 115.5 116.1 122.5 127.1 5.9 28.9 14.1 42.7 15.4 3.1 12.6 14.0 14.2 66.9 7.6 5.2 15.8 20.0 22.3 33.1 45.9 0.4 16.2 1.1 15.6 24.1 61.1 7.3 11.9 10.9 12.1 2.5 52.0 25.1 1.9 17.2 5.6 6.7 8.2 22.9 1.8 0.3 5.4 69.0 51.4 0.7 14.2 8.8 13.9 68.1 13.7 11.1 7.2 16.9 11.5 80.8 12.3 31.2 35.6 21.2 17.3 21.1 12.5 17.4 0.1 2.8 29.2 41.1 6.6 9.6 11.9 3.1 11.0 5.1 1.7 1.0 2.8 8.5 1.2 22.3 SCYL1 "GKLP, HT019, MGC78454, NKTL, NTKL, P105, TAPK, TEIF, TRAP" ENSG00000142186 "SCY1 like pseudokinase 1" Q96KG9 11 65525077-65538704 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "ER-Golgi transport, Transcription, Transcription regulation, Transport" "Activator, DNA-binding" "Mental retardation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 138.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015015 Uncertain Supported Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "HPA015015: AB_1856643" "unprognostic (5.56e-2)" "unprognostic (1.16e-1)" "unprognostic (1.03e-1)" "unprognostic (3.99e-1)" "unprognostic (1.23e-2)" "unprognostic (7.87e-2)" "unprognostic (1.23e-2)" "unprognostic (5.06e-2)" "unprognostic (1.14e-1)" "unprognostic (7.23e-2)" "unprognostic (4.41e-1)" "unprognostic (4.29e-1)" "unprognostic (7.86e-3)" "unprognostic (6.49e-3)" "unprognostic (4.27e-1)" "unprognostic (8.29e-2)" "unprognostic (2.29e-3)" 43.4 69.3 36.6 26.4 37.4 32.8 41.1 33.1 53.9 46.8 37.1 46.7 28.0 49.4 32.5 40.0 44.0 26.3 59.7 39.2 34.1 45.7 83.2 42.4 30.7 36.0 35.2 52.4 61.6 35.5 44.7 34.6 35.5 47.3 17.2 12.4 48.5 33.7 104.5 44.5 39.6 27.5 30.9 46.4 50.0 50.6 37.7 23.4 48.8 51.6 21.8 47.8 39.5 39.0 55.0 45.9 36.6 50.9 65.4 56.6 50.0 66.6 89.4 77.7 60.4 66.9 32.2 39.2 65.7 86.9 66.2 49.1 38.7 50.1 27.0 46.6 49.7 46.4 50.8 78.3 92.8 30.8 64.0 79.1 48.6 66.9 49.4 54.2 51.6 39.7 49.2 53.8 49.0 118.9 41.4 70.4 35.3 36.9 63.4 41.4 28.5 72.5 48.1 48.4 33.7 35.7 41.2 89.6 74.5 22.4 88.8 38.4 51.4 61.3 41.0 100.7 40.1 73.8 55.8 41.4 71.0 25.3 43.7 2.9 21.1 28.4 20.7 20.0 16.6 14.0 19.6 20.9 23.5 14.3 15.2 15.0 41.9 18.2 13.6 17.0 14.4 19.8 36.6 37.4 33.1 53.9 39.2 34.1 36.0 35.2 35.5 30.9 37.7 39.0 22.7 19.2 16.7 11.4 25.7 21.9 29.8 30.9 25.0 25.4 29.9 20.1 5.8 21.5 26.0 20.2 12.5 64.6 18.5 47.4 37.2 37.5 25.7 17.3 22.7 23.7 30.5 22.3 14.6 43.4 70.0 34.1 38.2 25.4 25.4 34.0 22.1 35.0 38.1 16.8 12.8 39.9 28.5 19.2 24.3 25.2 45.7 24.5 30.2 11.2 34.3 26.6 21.6 6.6 10.5 36.4 31.4 45.5 53.4 44.8 50.8 37.2 15.3 22.0 13.1 24.4 33.8 39.5 21.8 27.5 23.2 138.6 23.2 44.3 36.2 38.5 SDK1 FLJ31425 ENSG00000146555 "Sidekick cell adhesion molecule 1" Q7Z5N4 7 3301252-4269000 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 12.6" "Cell type enhanced" "Detected in many" "Early spermatids: 96.1;Excitatory neurons: 222.4;Inhibitory neurons: 551.0;Late spermatids: 190.0;Microglial cells: 201.4;Oligodendrocyte precursor cells: 112.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 8.5;BEWO: 10.5;RPTEC TERT1: 8.7;RT4: 11.2;SuSa: 10.3;U-2 OS: 13.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA011392 Approved Approved Cytosol NA NA 9500000 "Cluster 1: Neutrophils - Mixed function" "Cluster 25: Pancreas - Digestion" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA011392: AB_1856648" "unprognostic (2.39e-1)" "unprognostic (1.80e-2)" "unprognostic (1.44e-1)" "unprognostic (5.83e-2)" "unprognostic (2.15e-3)" "unprognostic (3.02e-2)" "unprognostic (1.23e-1)" "unprognostic (9.93e-3)" "unprognostic (1.63e-1)" "unprognostic (2.75e-1)" "prognostic favorable (4.08e-4)" "unprognostic (2.16e-1)" "unprognostic (2.49e-2)" "unprognostic (7.84e-2)" "unprognostic (1.59e-1)" "unprognostic (8.44e-2)" "unprognostic (1.37e-1)" 3.6 0.4 0.4 4.0 1.0 0.8 2.1 0.0 1.6 9.4 4.8 4.0 1.0 3.2 2.6 1.6 2.6 1.4 1.1 3.4 1.0 1.7 0.1 4.0 1.5 1.6 2.1 2.2 12.6 0.8 2.2 1.7 2.5 1.6 1.3 1.5 0.8 4.1 0.9 1.4 2.4 2.7 0.8 5.3 2.0 3.5 1.6 2.5 0.5 1.6 1.9 5.2 2.2 0.5 2.2 1.8 8.5 0.0 0.0 0.0 10.5 0.0 0.0 0.4 0.0 0.0 0.0 0.2 2.4 0.0 3.4 0.2 0.9 0.0 0.2 0.0 5.0 0.0 0.4 0.3 4.1 0.0 0.0 1.7 0.0 0.4 0.5 0.0 0.7 0.1 0.0 0.0 4.2 2.2 0.0 0.0 2.9 0.1 0.0 6.3 5.9 0.0 8.7 11.2 5.3 7.7 0.0 0.0 0.0 10.3 0.0 2.8 0.2 0.0 13.2 0.0 3.8 0.0 0.0 0.0 0.0 1.8 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 1.0 0.0 1.6 3.4 1.0 1.6 2.1 2.5 0.8 1.6 0.5 1.2 0.0 3.0 31.3 0.1 1.3 0.5 2.3 0.6 22.3 0.6 1.8 20.2 1.5 5.5 5.5 0.0 3.6 1.3 0.0 0.0 1.5 96.1 16.9 57.1 1.9 4.9 0.0 222.4 5.4 0.7 11.6 0.5 9.9 0.0 23.4 1.1 0.0 0.5 1.7 551.0 0.5 0.0 0.3 2.1 190.0 1.8 0.7 5.4 201.4 0.0 0.2 0.0 112.1 14.3 2.2 0.0 5.7 0.0 0.7 0.0 1.5 6.7 1.2 6.6 1.7 7.8 9.8 5.5 0.3 0.4 1.9 0.7 1.4 0.1 0.4 SDSL "cSDH, SDS-RS1" ENSG00000139410 "Serine dehydratase like" Q96GA7 12 113422380-113438276 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 104.6" "Cell type enhanced" "Detected in many" "Distal tubular cells: 78.2;Hepatocytes: 116.7;Hofbauer cells: 95.7;monocytes: 103.1;Proximal tubular cells: 115.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 8.7;intermediate monocyte: 10.0;myeloid DC: 18.5;plasmacytoid DC: 17.8" "Group enriched" "Detected in many" 6 "dendritic cells: 18.5;monocytes: 10.0" "Cell line enhanced" "Detected in many" "HMC-1: 51.4;MCF7: 90.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA005740 Approved Approved Cytosol NA NA 48000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 3: Monocytes - Immune response regulation" Cytosol "HPA005740: AB_10601486" "unprognostic (1.34e-1)" "unprognostic (8.33e-2)" "unprognostic (3.62e-2)" "unprognostic (3.54e-2)" "unprognostic (2.24e-2)" "unprognostic (6.17e-3)" "unprognostic (1.57e-1)" "unprognostic (6.46e-2)" "unprognostic (8.22e-2)" "unprognostic (2.00e-2)" "prognostic favorable (8.58e-4)" "unprognostic (2.93e-1)" "prognostic favorable (3.09e-5)" "unprognostic (2.22e-2)" "unprognostic (1.43e-1)" "unprognostic (2.54e-1)" "unprognostic (7.33e-2)" 4.5 33.1 12.7 7.1 14.2 3.2 4.9 16.4 15.2 4.6 10.8 12.2 16.8 4.8 9.9 2.5 7.9 7.7 12.8 11.8 16.1 34.9 104.6 5.7 3.4 18.7 16.2 4.6 18.7 12.4 15.5 4.4 16.0 8.5 8.5 2.4 4.8 6.6 3.0 1.3 12.2 5.2 15.8 5.8 9.1 10.6 16.4 1.5 23.9 1.3 1.7 6.2 1.4 17.4 8.5 33.3 4.7 14.1 0.9 1.9 3.2 4.8 1.2 5.2 4.4 14.1 8.7 0.4 24.2 8.1 14.4 8.6 2.2 11.4 1.7 20.5 8.4 22.1 8.5 6.3 27.5 2.8 51.4 4.4 16.0 12.8 18.8 5.9 8.0 0.0 17.3 6.6 6.5 90.2 0.1 10.2 4.6 9.6 14.6 0.0 7.0 16.5 13.6 10.6 1.5 0.5 20.6 23.6 18.4 4.2 28.6 24.8 7.2 6.2 11.9 26.9 4.2 1.4 1.4 0.3 26.3 8.4 7.8 0.2 8.7 0.0 0.0 10.0 0.0 2.2 0.0 0.0 18.5 0.1 0.0 0.0 0.4 1.8 1.3 17.8 0.3 2.5 12.7 14.2 16.4 15.2 11.8 16.1 18.7 16.2 16.0 15.8 16.4 17.4 1.2 0.0 5.1 2.0 3.1 0.9 2.2 7.0 0.0 0.5 15.3 10.2 18.2 27.1 6.3 29.5 2.1 16.3 4.9 43.7 78.2 36.1 0.5 14.8 7.7 4.0 31.8 10.1 1.3 20.1 3.0 4.5 12.8 10.1 43.8 15.3 6.4 116.7 95.7 3.3 0.6 36.4 4.1 18.1 8.4 1.5 2.8 36.9 3.6 1.9 103.1 33.5 0.0 1.5 2.0 16.2 63.2 5.7 0.0 6.1 63.2 115.7 3.8 2.6 0.0 0.2 7.3 0.2 0.4 1.1 0.6 7.3 1.9 29.5 31.0 5.9 SELENON "MDRS1, RSMD1, RSS, SELN, SEPN1" ENSG00000162430 "Selenoprotein N" Q9NZV5 1 25800176-25818221 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Desmin-related myopathy, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 99.2;Exocrine glandular cells: 42.3;Granulosa cells: 31.2;Hofbauer cells: 29.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058076 Approved Uncertain Cytosol "Intracellular and membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA058076: AB_2683598" "unprognostic (2.65e-1)" "unprognostic (1.75e-1)" "unprognostic (4.11e-1)" "prognostic favorable (2.23e-4)" "unprognostic (1.93e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (3.40e-5)" "unprognostic (1.94e-1)" "unprognostic (4.72e-1)" "unprognostic (3.32e-3)" "unprognostic (6.01e-2)" "unprognostic (3.07e-1)" "unprognostic (1.64e-1)" "unprognostic (1.53e-1)" "unprognostic (1.10e-1)" "unprognostic (5.56e-3)" "unprognostic (5.89e-2)" 65.7 48.0 51.6 34.0 51.2 17.0 60.8 45.5 53.3 43.8 74.2 42.5 17.4 48.8 19.5 36.5 40.2 30.1 60.7 49.6 48.5 52.5 20.3 51.8 20.5 72.8 55.2 51.7 60.1 37.0 40.2 38.9 52.1 58.2 20.8 11.7 45.7 39.6 56.3 30.2 31.0 56.2 54.1 43.4 43.4 12.0 62.6 13.6 53.8 39.7 16.3 46.9 35.6 50.2 52.6 49.5 160.9 138.4 102.5 178.8 54.4 62.2 93.4 67.7 53.9 12.9 54.2 0.1 40.4 94.6 74.8 49.9 42.4 66.2 51.1 55.8 32.6 51.4 18.2 16.0 73.8 11.0 116.6 191.7 43.8 71.0 35.5 79.9 214.4 17.4 18.5 7.2 64.7 26.8 2.3 15.7 61.0 40.9 33.7 45.4 70.3 6.4 27.7 14.8 33.5 56.9 39.4 35.3 52.7 43.0 35.6 36.1 180.5 68.4 46.2 126.6 37.1 5.8 0.2 1.4 94.8 15.9 84.4 2.7 1.2 1.6 0.7 1.0 0.4 0.7 0.6 0.5 0.8 0.4 0.9 0.6 0.2 0.3 1.1 0.1 0.7 0.4 51.6 51.2 45.5 53.3 49.6 48.5 72.8 55.2 52.1 54.1 62.6 50.2 99.2 9.6 10.3 0.0 2.0 0.0 0.0 0.0 0.0 0.0 23.0 19.3 0.0 0.0 3.7 20.2 0.0 16.4 3.8 0.0 0.0 18.6 0.0 6.5 22.4 21.5 0.0 0.0 0.0 42.3 11.4 12.5 0.0 13.5 2.5 31.2 0.0 0.0 29.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 3.1 0.0 0.0 0.0 0.0 24.8 0.0 0.0 0.9 0.0 0.0 14.9 3.6 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 13.0 2.2 8.6 0.0 0.0 SELL "CD62L, hLHRc, LAM-1, LAM1, Leu-8, LNHR, LSEL, Lyam-1, LYAM1, PLNHR" ENSG00000188404 "Selectin L" P14151 1 169690665-169711702 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 150.4;lymphoid tissue: 231.4" "Group enriched" "Detected in many" 5 "B-cells: 221.4;dendritic cells: 206.0;Kupffer cells: 68.9;Macrophages: 86.3;monocytes: 208.7;NK-cells: 110.2;T-cells: 104.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 11.2;JURKAT: 29.4;MOLT-4: 21.2;U-266/70: 38.8;U-698: 19.4;U-937: 11.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002144, HPA051972" Enhanced Uncertain Cytosol NA NA 4700000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "CAB002144: AB_563862, HPA051972: AB_2797242" "prognostic favorable (3.76e-4)" "prognostic favorable (2.25e-4)" "unprognostic (1.52e-2)" "unprognostic (2.89e-2)" "unprognostic (7.87e-3)" "prognostic favorable (6.43e-4)" "unprognostic (1.39e-3)" "unprognostic (3.43e-1)" "unprognostic (2.70e-3)" "prognostic favorable (3.14e-4)" "unprognostic (1.42e-1)" "unprognostic (4.21e-2)" "prognostic unfavorable (4.96e-5)" "unprognostic (4.76e-2)" "unprognostic (8.71e-3)" "unprognostic (9.57e-2)" "unprognostic (1.01e-1)" 29.3 2.3 2.8 118.8 4.5 150.4 2.6 8.4 6.2 3.7 2.7 6.8 3.2 2.6 1.7 5.5 4.7 24.1 3.1 3.2 4.0 3.0 12.1 19.4 231.4 7.4 4.5 1.0 3.7 28.0 13.9 11.2 6.1 3.7 7.1 1.0 3.8 1.9 3.4 0.6 17.0 14.5 6.4 166.8 5.6 1.1 3.9 132.2 2.8 13.6 202.0 37.9 1.4 8.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.2 0.2 0.7 0.0 0.3 11.2 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 7.7 1.3 0.5 0.0 0.0 0.0 0.0 1.8 29.4 0.1 1.4 0.0 1.8 21.2 0.3 0.1 0.4 0.3 7.8 0.2 0.7 6.1 0.3 0.0 0.0 0.0 1.4 0.0 0.8 0.0 0.0 0.0 0.6 0.2 0.0 0.0 38.8 0.0 19.4 2.0 11.1 0.3 3688.4 992.6 1696.7 284.3 211.6 78.1 613.0 528.9 294.2 756.3 734.4 1169.2 683.6 4201.4 2551.1 93.1 622.9 1011.2 2052.5 2.8 4.5 8.4 6.2 3.2 4.0 7.4 4.5 6.1 6.4 3.9 8.0 1.8 9.6 13.7 0.7 221.4 0.4 0.3 0.0 0.6 0.1 0.5 0.3 0.6 2.8 1.8 11.0 0.0 13.9 206.0 0.1 0.0 0.2 0.0 0.1 0.0 3.4 0.0 25.2 0.2 0.0 0.6 3.3 2.6 0.1 10.1 0.5 3.9 1.1 5.6 0.0 0.1 0.1 0.0 68.9 2.7 0.2 0.6 86.3 1.8 1.0 208.7 2.5 110.2 0.0 0.8 0.1 0.0 0.0 25.8 0.0 0.0 0.9 1.5 0.0 0.0 0.2 0.6 0.0 0.1 0.3 0.1 28.5 104.9 0.5 0.0 0.6 SEM1 "C7orf76, DSS1, ECD, FLJ42280, SHFD1, Shfdg1, SHFM1, SHSF1" ENSG00000127922 "SEM1 26S proteasome complex subunit" "P60896, Q6ZVN7" 7 96481626-96709891 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 636.7;Endometrial ciliated cells: 571.3;Exocrine glandular cells: 537.4;Extravillous trophoblasts: 712.8;Pancreatic endocrine cells: 543.9;Proximal tubular cells: 533.4;Syncytiotrophoblasts: 872.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA020429, HPA072648" Uncertain Approved Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA020429: AB_1859527, HPA072648: AB_2686543" "unprognostic (5.41e-3)" "unprognostic (6.25e-2)" "unprognostic (1.62e-2)" "unprognostic (2.14e-3)" "unprognostic (1.24e-3)" "unprognostic (6.16e-3)" "unprognostic (4.29e-1)" "unprognostic (1.17e-1)" "unprognostic (1.43e-1)" "prognostic favorable (2.52e-4)" "unprognostic (4.55e-1)" "unprognostic (6.92e-2)" "prognostic unfavorable (7.19e-4)" "unprognostic (1.32e-1)" "unprognostic (2.67e-2)" "unprognostic (2.64e-1)" "prognostic favorable (8.00e-5)" 137.1 178.9 100.5 118.2 101.2 77.8 124.2 101.7 161.4 135.9 100.3 146.0 121.8 132.5 118.5 193.9 114.9 34.8 193.2 98.4 108.9 130.0 262.8 102.7 87.9 102.6 107.5 167.3 103.7 105.5 122.2 106.7 103.0 118.2 77.8 85.0 131.4 69.0 360.5 144.8 116.1 64.2 98.6 96.9 126.7 183.7 101.2 136.8 106.6 150.2 84.7 113.4 144.8 104.0 570.7 327.0 448.1 468.1 187.4 162.3 241.7 453.4 220.0 186.9 232.5 298.3 459.4 373.6 1096.4 222.8 575.9 288.2 379.5 306.5 263.6 437.4 285.9 448.3 505.7 472.5 171.2 670.0 321.4 208.4 233.7 279.8 283.7 291.4 253.8 438.4 592.4 444.7 193.0 716.9 760.9 942.6 607.0 572.4 297.3 291.6 576.4 441.1 273.2 555.6 367.8 463.6 845.0 701.6 497.9 681.4 200.6 502.2 525.6 365.3 641.2 683.1 575.0 278.3 818.9 1080.9 399.4 574.3 515.8 292.6 385.3 109.0 279.9 443.1 268.4 336.4 363.1 332.7 570.6 312.5 282.4 284.0 27.0 300.4 392.8 622.8 546.6 375.7 100.5 101.2 101.7 161.4 98.4 108.9 102.6 107.5 103.0 98.6 101.2 104.0 288.2 173.1 224.5 0.0 47.2 0.0 0.0 0.0 0.0 0.0 212.6 325.2 0.0 0.0 103.4 244.6 0.0 636.7 93.1 0.0 412.8 382.5 0.0 571.3 314.1 127.6 0.0 0.0 0.0 537.4 712.8 129.5 0.0 450.0 102.2 258.9 0.0 0.0 393.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 123.0 0.0 0.0 241.3 0.0 0.0 0.0 0.0 543.9 0.0 0.0 19.6 0.0 0.0 533.4 149.4 0.0 0.0 0.0 140.3 0.0 0.0 0.0 0.0 872.3 65.9 187.2 0.0 0.0 SEMA5B "FLJ10372, KIAA1445, SEMAG, SemG" ENSG00000082684 "Semaphorin 5B" Q9P283 3 122909082-123028605 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.2" "Cell type enhanced" "Detected in some" "Astrocytes: 9.4;Excitatory neurons: 30.8;Muller glia cells: 7.3;Oligodendrocyte precursor cells: 45.2;Smooth muscle cells: 14.3" "Cancer enhanced" "Detected in many" "renal cancer: 18.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 79.7;NTERA-2: 15.7;SH-SY5Y: 21.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA066548 Enhanced Supported Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA066548: AB_2685689" "unprognostic (7.34e-2)" "unprognostic (1.84e-3)" "unprognostic (1.92e-4)" "unprognostic (3.01e-2)" "unprognostic (1.04e-1)" "unprognostic (2.28e-1)" "unprognostic (4.72e-2)" "unprognostic (1.58e-2)" "unprognostic (7.66e-3)" "unprognostic (2.87e-2)" "unprognostic (4.71e-2)" "unprognostic (2.58e-1)" "prognostic unfavorable (7.57e-4)" "unprognostic (1.31e-3)" "unprognostic (5.96e-2)" "unprognostic (6.12e-2)" "unprognostic (2.12e-1)" 1.7 1.5 12.1 0.4 11.8 0.0 1.3 7.3 15.9 1.8 6.7 1.3 0.9 1.4 2.8 0.7 3.5 2.5 9.5 16.2 8.0 9.1 0.9 1.2 0.6 8.4 8.5 1.4 1.7 0.6 2.7 2.6 9.7 1.4 0.8 7.1 0.4 1.4 0.9 1.5 1.5 1.9 7.7 0.2 0.6 0.7 7.8 0.2 2.6 0.5 0.6 1.6 1.6 10.9 0.0 0.0 79.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.3 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 15.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 21.3 0.0 0.2 0.0 3.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 11.8 7.3 15.9 16.2 8.0 8.4 8.5 9.7 7.7 7.8 10.9 1.2 0.0 1.1 9.4 0.0 0.0 0.0 0.1 0.0 7.2 0.1 0.0 3.5 1.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.8 0.0 0.0 30.8 0.0 0.3 0.7 0.0 0.0 0.0 0.1 1.8 0.0 0.1 0.0 6.6 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 1.9 0.6 7.3 0.0 45.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.1 14.3 0.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 SENP2 "AXAM2, DKFZp762A2316, KIAA1331, SMT3IP2" ENSG00000163904 "SUMO specific peptidase 2" Q9HC62 3 185582496-185633551 "Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport, Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 249.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029247, HPA029248" Approved Supported Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 5: NTERA-2 - Transcription" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "HPA029247: AB_10599305, HPA029248: AB_10601855" "unprognostic (4.57e-2)" "unprognostic (1.84e-2)" "unprognostic (6.80e-2)" "prognostic unfavorable (7.98e-5)" "unprognostic (7.85e-2)" "unprognostic (2.90e-2)" "unprognostic (4.41e-3)" "unprognostic (1.45e-1)" "unprognostic (1.59e-1)" "unprognostic (1.46e-1)" "unprognostic (1.85e-1)" "unprognostic (8.41e-3)" "unprognostic (5.12e-2)" "unprognostic (6.92e-2)" "unprognostic (1.60e-1)" "unprognostic (1.92e-1)" "unprognostic (1.56e-1)" 7.4 7.3 13.4 4.4 15.8 10.7 7.5 13.3 16.2 6.0 12.0 7.8 6.0 6.1 9.7 6.5 7.2 4.5 8.3 13.9 13.1 7.3 9.5 6.4 6.2 12.9 13.6 10.0 7.4 9.6 10.5 9.0 12.4 6.6 6.1 12.8 7.6 6.3 18.9 9.2 6.6 4.8 12.2 6.7 8.0 15.1 14.2 8.1 7.2 13.0 6.0 7.1 6.3 14.4 24.4 4.6 11.6 13.4 20.6 13.8 15.1 10.9 12.6 13.8 14.6 18.3 7.5 13.2 20.3 10.2 23.6 12.6 24.3 9.0 20.3 9.7 11.6 8.9 9.8 11.0 10.9 13.2 5.6 8.6 13.3 7.8 9.5 10.2 9.6 12.5 10.8 18.1 12.0 12.0 11.4 14.7 42.4 12.3 8.1 13.1 15.8 22.1 7.7 7.9 11.9 13.4 9.3 20.4 18.3 23.0 27.8 17.5 6.1 9.0 9.8 16.4 17.7 20.9 26.8 23.8 14.9 13.9 12.5 5.1 1.3 2.6 1.6 1.3 1.6 1.3 1.3 1.3 1.0 1.9 1.5 1.5 3.4 2.3 1.6 2.0 1.3 0.9 13.4 15.8 13.3 16.2 13.9 13.1 12.9 13.6 12.4 12.2 14.2 14.4 12.3 28.9 27.4 17.9 21.2 10.8 23.7 12.6 6.2 22.8 21.6 15.4 24.2 11.5 26.2 9.2 31.3 25.0 22.6 15.7 5.9 12.9 249.6 26.3 12.0 12.8 5.4 11.1 42.9 15.2 19.9 16.1 15.3 25.2 10.8 21.3 17.2 20.5 13.2 11.8 43.0 15.1 14.2 12.5 9.1 43.0 22.7 11.1 17.8 26.2 13.6 17.8 21.6 41.2 41.3 17.9 6.6 17.7 25.7 17.0 24.2 18.2 28.8 38.1 19.7 23.2 16.3 84.2 31.8 13.4 12.5 39.7 18.2 33.7 15.8 22.5 SEPTIN11 "FLJ10849, SEPT11" ENSG00000138758 "Septin 11" Q9NVA2 4 76949751-77040384 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 90.1;Extravillous trophoblasts: 266.8;Fibroblasts: 40.1;Hofbauer cells: 52.0;Syncytiotrophoblasts: 60.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ: 495.8;fHDF/TERT166: 604.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003459, HPA005665" Approved Approved Cytosol NA NA 2800000 "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA003459: AB_1856696, HPA005665: AB_1079910" "unprognostic (1.69e-1)" "unprognostic (2.93e-1)" "unprognostic (3.39e-3)" "unprognostic (4.36e-2)" "unprognostic (1.00e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.70e-5)" "unprognostic (1.79e-1)" "unprognostic (6.04e-3)" "unprognostic (1.58e-2)" "unprognostic (2.58e-2)" "unprognostic (5.85e-2)" "prognostic favorable (2.40e-4)" "unprognostic (5.70e-3)" "unprognostic (6.84e-2)" "unprognostic (1.55e-1)" "unprognostic (2.57e-1)" 84.8 13.0 34.6 27.5 46.5 7.9 39.3 24.3 51.4 40.4 0.0 50.1 21.8 33.8 18.0 22.5 17.4 45.4 30.8 40.5 13.7 52.4 33.9 40.5 24.1 5.2 8.5 20.0 22.3 17.3 11.3 84.1 4.5 21.0 40.4 22.3 11.6 26.1 26.0 13.3 35.3 40.6 0.0 25.6 25.2 7.8 16.6 12.7 21.1 18.3 22.8 39.3 21.5 50.6 87.6 34.9 328.1 293.8 192.8 152.9 94.6 495.8 382.7 110.6 154.5 64.3 62.9 2.0 100.9 604.4 51.9 36.6 109.8 73.8 171.2 114.0 36.7 171.2 44.6 47.1 168.0 93.0 69.7 195.5 34.4 160.2 59.8 87.7 169.0 34.3 72.0 46.6 331.2 50.4 122.8 3.3 111.1 71.4 18.1 142.6 372.8 10.1 62.6 94.0 112.1 83.6 96.2 54.4 77.9 209.9 49.5 37.3 184.4 368.7 109.4 182.8 93.1 28.5 24.3 1.1 140.5 10.0 76.4 12.2 2.4 32.5 8.1 2.2 5.0 3.6 9.2 11.2 7.8 6.7 3.5 9.4 0.6 38.4 7.4 20.8 5.8 6.6 34.6 46.5 24.3 51.4 40.5 13.7 5.2 8.5 4.5 0.0 16.6 50.6 33.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 90.1 24.6 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 266.8 40.1 0.0 0.0 0.0 0.0 0.0 0.0 52.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.9 0.0 0.0 0.0 0.0 60.5 5.6 0.0 0.0 0.0 SEPTIN6 "KIAA0128, MGC16619, MGC20339, SEP2, SEPT2, SEPT6" ENSG00000125354 "Septin 6" Q14141 X 119615724-119693370 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Host-virus interaction, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 231.3" "Cell type enhanced" "Detected in some" "B-cells: 20.3;Cytotrophoblasts: 43.9;dendritic cells: 66.5;Extravillous trophoblasts: 50.1;Hofbauer cells: 54.8;Plasma cells: 28.4;Syncytiotrophoblasts: 43.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "JURKAT: 273.0;MOLT-4: 300.5;REH: 271.8;SH-SY5Y: 394.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003459, HPA005665" Supported Approved Cytosol NA NA 2900000 "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA003459: AB_1856696, HPA005665: AB_1079910" "unprognostic (6.35e-3)" "unprognostic (1.64e-3)" "unprognostic (1.38e-1)" "unprognostic (9.61e-2)" "unprognostic (1.15e-1)" "unprognostic (3.09e-1)" "unprognostic (1.73e-1)" "unprognostic (6.23e-2)" "unprognostic (2.13e-1)" "unprognostic (7.24e-2)" "unprognostic (6.27e-2)" "unprognostic (1.46e-1)" "unprognostic (1.95e-1)" "unprognostic (2.55e-1)" "unprognostic (2.88e-1)" "unprognostic (1.92e-1)" "unprognostic (2.60e-2)" 13.1 73.4 14.5 66.7 12.8 61.1 12.7 16.9 16.9 11.5 7.8 47.4 14.3 11.2 16.9 17.9 18.1 17.5 16.1 12.4 20.8 18.1 21.3 16.5 119.7 18.3 18.0 11.4 4.6 9.9 9.8 14.7 22.1 13.4 18.5 38.9 18.2 40.5 4.6 7.1 35.3 24.4 13.5 61.9 20.0 40.3 20.5 231.3 7.6 5.9 103.9 18.6 9.7 12.0 6.5 10.1 37.9 68.5 3.5 7.7 53.9 18.9 41.7 31.4 53.8 3.4 14.4 130.7 14.6 23.9 32.6 3.7 60.2 12.1 21.7 80.6 13.9 58.1 20.3 23.5 9.1 66.3 29.4 14.0 2.6 24.8 0.6 13.1 46.4 273.0 43.6 68.0 18.7 4.8 300.5 38.6 40.2 1.9 31.0 271.8 31.3 106.7 33.5 6.8 16.8 394.7 49.1 17.9 20.6 40.7 24.3 33.8 29.0 8.5 17.2 27.5 4.7 33.8 14.5 170.7 0.8 69.0 6.3 34.2 17.2 39.9 58.6 26.1 61.4 65.0 75.3 68.6 34.0 64.0 79.3 69.4 11.8 81.3 38.8 63.7 112.4 53.9 14.5 12.8 16.9 16.9 12.4 20.8 18.3 18.0 22.1 13.5 20.5 12.0 13.8 0.0 0.0 0.0 20.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 43.9 66.5 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 50.1 7.1 0.0 0.0 0.0 0.0 0.0 0.0 54.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 43.0 15.5 0.0 0.0 0.0 SERBP1 "CGI-55, CHD3IP, DKFZP564M2423, HABP4L, PAI-RBP1, PAIRBP1" ENSG00000142864 "SERPINE1 mRNA binding protein 1" Q8NC51 1 67407810-67430415 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020559, CAB026297" Supported Enhanced Cytosol NA NA 810000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB026297: AB_425924, HPA020559: AB_1856701" "unprognostic (1.58e-1)" "unprognostic (6.35e-2)" "unprognostic (1.45e-2)" "unprognostic (6.80e-3)" "unprognostic (2.71e-3)" "unprognostic (3.59e-1)" "prognostic unfavorable (1.36e-4)" "unprognostic (1.98e-2)" "unprognostic (1.32e-3)" "unprognostic (5.97e-2)" "unprognostic (8.25e-3)" "unprognostic (3.04e-1)" "unprognostic (1.33e-2)" "unprognostic (1.40e-2)" "unprognostic (4.76e-1)" "unprognostic (6.64e-2)" "unprognostic (1.34e-3)" 116.2 79.6 45.9 110.1 48.9 130.5 106.9 45.7 48.5 98.3 44.4 91.2 99.6 89.9 65.7 188.2 81.5 66.5 93.4 42.5 46.5 85.9 131.4 76.6 123.8 51.6 47.5 86.8 121.1 131.5 48.0 92.9 52.4 77.3 84.5 47.6 119.0 66.2 336.9 149.6 92.7 82.1 50.3 81.4 94.1 82.9 49.3 125.7 91.1 159.0 118.1 101.4 118.4 52.8 444.4 272.4 274.9 280.4 236.9 214.0 420.9 452.9 163.8 294.7 241.6 524.8 195.4 828.9 341.1 236.0 294.6 337.4 435.2 411.2 309.5 375.7 535.8 764.1 488.7 460.7 207.0 614.9 290.8 221.3 272.1 384.6 356.0 205.9 319.7 276.0 867.4 293.0 236.2 314.9 494.9 412.9 978.1 298.1 355.2 566.3 600.4 429.8 231.0 349.8 468.8 330.8 351.0 385.6 442.4 231.1 212.0 386.4 345.9 283.4 351.5 421.2 618.3 273.6 369.2 747.9 233.0 603.3 326.9 37.8 84.1 53.7 100.4 92.5 125.4 101.3 99.0 100.9 107.5 102.1 114.6 105.6 27.1 147.4 90.1 98.2 131.5 119.2 45.9 48.9 45.7 48.5 42.5 46.5 51.6 47.5 52.4 50.3 49.3 52.8 251.3 250.0 225.5 17.6 262.6 686.4 437.3 363.8 536.7 146.7 262.1 251.8 144.8 214.4 311.4 117.7 91.8 271.5 343.7 200.0 242.6 324.4 555.9 368.1 411.9 314.9 230.1 398.8 24.1 361.5 531.0 231.0 169.7 400.5 219.2 215.6 179.2 331.5 297.9 143.0 24.6 338.7 183.1 247.7 281.2 240.9 221.2 214.2 192.1 27.2 298.4 153.6 325.4 26.7 33.2 349.3 192.0 278.7 277.4 540.5 168.4 323.0 206.3 139.7 138.1 301.6 516.0 569.8 281.6 597.9 719.7 229.3 271.4 318.8 405.0 470.2 SERINC1 "KIAA1253, TDE1L, TDE2, TMS-2" ENSG00000111897 "Serine incorporator 1" Q9NRX5 6 122443351-122471807 "Plasma proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035738, HPA035739" Uncertain Approved Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA035738: AB_10672990, HPA035739: AB_10669536" "unprognostic (2.83e-3)" "unprognostic (2.68e-3)" "unprognostic (1.59e-1)" "unprognostic (7.67e-2)" "unprognostic (2.65e-1)" "unprognostic (2.84e-2)" "unprognostic (2.04e-1)" "unprognostic (7.45e-2)" "unprognostic (9.84e-2)" "unprognostic (8.27e-2)" "unprognostic (9.07e-3)" "unprognostic (2.84e-1)" "unprognostic (5.50e-3)" "unprognostic (1.80e-3)" "unprognostic (9.22e-2)" "unprognostic (3.58e-1)" "unprognostic (1.00e-2)" 213.6 242.8 220.4 93.2 248.8 148.2 157.8 237.5 334.0 151.4 178.5 104.6 99.4 146.6 108.1 94.9 104.4 128.0 163.7 248.3 257.3 194.1 241.3 160.5 96.8 258.9 243.3 164.4 100.4 243.3 71.7 195.1 282.9 139.6 100.1 225.5 97.1 143.3 152.6 79.0 114.3 141.7 268.4 123.6 96.5 65.6 241.3 89.7 203.1 194.8 79.5 121.7 84.8 306.8 40.5 49.1 121.7 111.8 450.2 245.1 64.5 208.4 259.8 111.6 171.6 57.8 106.9 27.1 159.7 236.5 127.9 78.7 72.6 90.2 166.1 87.1 86.0 76.9 79.0 105.9 201.3 77.5 146.3 256.7 173.0 139.0 190.8 256.4 98.1 69.9 77.4 149.3 233.8 46.8 35.1 51.4 39.7 63.5 61.9 42.5 60.0 66.5 240.3 70.1 63.6 114.5 92.3 101.2 146.8 107.4 70.0 107.1 201.3 133.7 57.9 110.8 109.9 112.4 134.4 35.9 176.8 62.1 159.5 158.3 43.0 92.6 44.7 53.2 48.1 27.7 45.9 43.3 35.9 23.7 53.2 46.9 108.7 51.7 62.0 28.0 54.2 56.0 220.4 248.8 237.5 334.0 248.3 257.3 258.9 243.3 282.9 268.4 241.3 306.8 167.8 150.6 99.2 44.4 73.9 66.2 81.1 55.7 61.5 114.4 71.7 57.1 156.2 87.2 58.9 77.3 70.9 53.8 80.9 88.8 9.8 63.0 3.2 54.9 103.3 130.0 84.5 81.5 92.5 48.7 57.7 131.4 39.8 106.8 124.0 58.1 127.8 132.1 73.1 138.0 145.7 41.8 36.7 158.2 86.4 10.0 126.8 107.4 94.3 65.6 58.1 97.2 58.7 48.2 134.0 78.4 43.6 131.3 80.0 86.1 80.1 44.0 56.1 70.6 59.2 105.1 110.6 25.7 17.0 39.0 74.9 119.7 100.7 99.8 32.7 97.1 SERPINE1 "PAI, PAI1, PLANH1" ENSG00000106366 "Serpin family E member 1" P05121 7 101127104-101139247 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 418.0" "Cell type enhanced" "Detected in many" "Endothelial cells: 165.1;Fibroblasts: 162.1;Pancreatic endocrine cells: 231.8;Smooth muscle cells: 239.3;Syncytiotrophoblasts: 651.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 20 "NK-cell: 9.5" "Lineage enriched" "Detected in single" 20 "NK-cells: 9.5" "Cell line enhanced" "Detected in many" "BJ: 3483.8;HUVEC TERT2: 4014.7;LHCN-M2: 3874.5;TIME: 10032.6;U-138 MG: 4609.6;U-251 MG: 4256.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA050039, CAB068501" Uncertain Approved Cytosol "Secreted to blood" No No 142000000 13000000 "Cluster 22: NK-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 33: Fibroblasts - ECM organization" Cytosol "CAB068501: AB_1642775, HPA050039: AB_2680997" "unprognostic (5.02e-2)" "prognostic unfavorable (5.01e-4)" "prognostic unfavorable (2.82e-4)" "unprognostic (2.10e-2)" "unprognostic (9.04e-3)" "prognostic unfavorable (2.84e-5)" "unprognostic (6.80e-3)" "prognostic unfavorable (4.41e-6)" "unprognostic (2.33e-1)" "unprognostic (1.45e-1)" "unprognostic (2.88e-3)" "unprognostic (1.58e-1)" "prognostic unfavorable (5.88e-8)" "prognostic unfavorable (3.27e-6)" "unprognostic (1.05e-1)" "unprognostic (4.33e-2)" "prognostic unfavorable (5.51e-4)" 215.5 75.3 3.1 91.6 3.4 1.7 56.2 5.2 12.8 62.1 5.0 31.7 7.4 31.1 1.0 16.4 41.3 360.3 136.0 3.9 6.6 166.2 345.8 260.2 21.3 6.4 3.7 105.6 135.1 11.8 12.3 418.0 4.5 37.8 5.4 4.9 10.6 8.0 17.8 21.2 13.1 74.3 4.8 13.8 30.3 5.5 12.7 6.7 59.5 4.3 3.5 359.9 19.2 6.0 77.3 64.4 1.2 5.1 766.6 1511.0 89.3 3483.8 654.6 1717.6 1487.4 9.4 5.5 2.7 812.6 1117.9 2367.3 18.1 0.4 269.4 1756.2 4.3 0.7 1.1 5.2 61.4 1532.6 0.2 3.8 596.1 106.9 2641.4 1374.8 928.5 4014.7 0.2 6.4 2.5 3874.5 0.4 0.6 2.2 18.2 1.3 41.7 0.6 6.1 4.8 5.1 30.3 1.0 0.8 286.3 77.2 8.3 410.9 3.3 9.9 10032.6 4609.6 204.0 1593.8 4256.0 0.6 2.9 4.2 1150.5 2.4 45.9 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 9.5 0.0 0.3 0.0 0.8 3.1 3.4 5.2 12.8 3.9 6.6 6.4 3.7 4.5 4.8 12.7 6.0 35.8 0.0 7.7 0.0 1.1 40.0 43.7 97.4 14.2 0.3 0.3 2.3 2.5 4.3 11.0 5.5 0.0 56.0 1.0 0.4 0.0 65.1 0.0 4.7 53.8 165.1 5.3 0.0 0.5 4.5 75.1 162.1 0.5 3.2 10.2 12.4 40.4 112.3 15.9 0.0 0.3 0.2 8.2 4.6 9.6 1.1 17.7 11.1 7.2 5.6 1.1 0.7 0.0 0.0 0.0 231.8 0.0 12.0 3.6 9.7 0.1 0.0 8.2 0.3 39.5 55.4 239.3 0.0 0.1 9.0 24.7 651.7 2.3 2.1 0.5 8.1 SERPINI1 PI12 ENSG00000163536 "Serpin family I member 1" Q99574 3 167735243-167825569 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 301.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 219.4;Excitatory neurons: 176.9;Inhibitory neurons: 228.8;Oligodendrocytes: 174.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 29.2;Karpas-707: 29.1;U-266/84: 28.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001565, HPA056092" Enhanced Uncertain Cytosol "Secreted in brain" NA NA 750000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 65: Brain - Ion transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 56: Bipolar cells - Visual perception" Cytosol "HPA001565: AB_1079924, HPA056092: AB_2683036" "unprognostic (1.61e-1)" "unprognostic (1.06e-1)" "unprognostic (4.09e-3)" "unprognostic (1.35e-1)" "unprognostic (6.97e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (4.25e-4)" "unprognostic (2.48e-1)" "unprognostic (2.61e-1)" "unprognostic (6.07e-3)" "unprognostic (2.18e-2)" "unprognostic (1.01e-1)" "unprognostic (1.58e-3)" "unprognostic (1.41e-1)" "unprognostic (2.89e-1)" "unprognostic (1.22e-1)" "unprognostic (1.11e-1)" 13.1 15.8 138.8 4.1 157.7 2.3 11.7 115.9 301.4 8.4 82.1 5.1 2.2 8.6 8.2 5.5 7.9 6.3 14.0 162.0 129.1 32.1 4.1 6.4 4.6 122.8 153.6 6.9 39.5 6.9 42.8 6.7 123.9 11.8 4.4 84.4 23.0 7.4 3.2 3.1 4.4 6.1 134.6 8.7 10.8 15.8 134.5 4.4 11.2 8.1 8.2 4.9 6.0 164.8 0.8 3.5 5.5 0.4 10.3 2.2 0.3 1.9 2.7 1.3 2.2 1.5 5.9 29.2 9.5 1.3 4.5 1.3 3.9 3.8 1.5 7.7 6.5 8.9 22.5 10.7 0.7 1.4 1.1 3.8 1.4 0.8 1.3 2.9 0.4 10.5 18.9 29.1 1.2 2.7 0.8 1.9 3.3 4.2 4.5 2.7 0.4 3.2 11.2 1.0 2.2 13.4 3.6 6.8 8.3 12.4 10.6 4.4 1.0 5.5 0.5 0.5 10.3 23.0 28.4 18.8 4.2 7.7 3.2 1.5 0.3 0.8 9.3 0.7 6.9 22.1 9.7 10.2 0.5 25.2 6.9 8.1 0.9 9.5 0.5 7.2 27.2 5.2 138.8 157.7 115.9 301.4 162.0 129.1 122.8 153.6 123.9 134.6 134.5 164.8 49.8 6.4 1.5 43.1 10.7 3.7 13.2 6.4 14.2 219.4 3.6 14.1 8.2 1.5 6.7 5.5 14.6 6.1 6.2 0.7 7.9 1.8 0.4 2.0 1.0 16.0 4.8 7.4 176.9 18.0 6.0 8.9 2.6 1.7 2.5 2.3 3.9 0.6 2.3 5.0 228.8 0.3 73.2 0.6 3.2 2.4 4.1 0.9 7.2 25.3 1.2 78.0 2.1 31.2 174.7 3.0 0.0 2.6 14.6 6.7 0.0 39.9 13.6 35.4 26.3 5.2 54.7 3.0 27.4 0.5 1.7 5.1 6.2 1.1 0.3 2.3 SESN2 "DKFZp761M0212, HI95, SES2, SEST2" ENSG00000130766 "Sestrin 2" P58004 1 28259518-28282491 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 66.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 46.5;SK-MEL-30: 58.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018191 Uncertain Approved Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA018191: AB_1856750" "unprognostic (7.05e-2)" "unprognostic (4.95e-3)" "unprognostic (1.43e-1)" "unprognostic (1.37e-1)" "unprognostic (1.37e-1)" "unprognostic (1.71e-1)" "prognostic unfavorable (4.78e-4)" "unprognostic (8.97e-2)" "unprognostic (2.50e-3)" "unprognostic (1.41e-1)" "unprognostic (1.80e-2)" "unprognostic (2.39e-2)" "unprognostic (1.71e-1)" "unprognostic (2.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.84e-1)" "unprognostic (1.60e-1)" 10.9 9.0 6.4 2.9 6.3 19.4 8.5 5.8 7.5 7.4 5.2 10.1 7.6 8.2 1.6 20.0 7.9 3.3 6.3 5.9 7.1 15.9 24.7 9.6 2.0 7.5 7.5 27.9 10.6 4.4 6.6 4.8 6.9 6.2 4.0 1.4 8.5 1.9 7.6 5.3 8.8 2.9 6.8 6.9 11.1 10.7 9.5 2.4 5.3 2.4 2.0 7.6 8.8 7.1 5.6 3.0 7.1 11.8 11.3 8.9 38.6 10.5 9.6 6.3 7.4 4.3 4.0 6.3 4.3 4.8 7.0 5.5 8.3 7.4 4.3 5.7 7.7 2.6 4.3 7.3 37.0 9.5 13.7 28.1 46.5 16.9 40.0 2.9 7.0 14.6 15.2 29.3 5.9 3.2 3.5 2.6 5.7 2.6 6.0 5.3 1.9 14.6 4.2 9.3 2.4 2.8 3.0 2.4 58.5 7.8 6.5 13.4 4.1 3.2 9.9 7.3 6.4 37.9 10.4 10.0 7.5 9.5 7.2 0.0 1.5 1.3 5.7 1.2 2.7 1.1 2.0 2.8 1.5 0.7 1.2 2.5 3.9 2.5 1.9 1.7 2.4 1.8 6.4 6.3 5.8 7.5 5.9 7.1 7.5 7.5 6.9 6.8 9.5 7.1 26.4 0.0 5.0 3.6 9.9 17.0 21.1 14.2 26.7 11.6 21.4 15.1 7.3 12.8 9.0 7.3 8.4 31.2 30.6 35.9 3.9 24.3 6.5 11.8 8.9 7.8 13.1 2.7 3.9 16.9 27.0 11.8 13.7 12.1 4.5 10.9 9.3 19.8 13.8 0.0 6.1 11.2 16.2 5.7 22.2 3.7 2.5 20.0 7.2 4.7 5.9 6.6 9.2 3.5 1.4 31.9 15.2 3.4 13.0 13.6 27.7 23.4 8.3 7.8 0.0 7.9 14.3 5.6 12.5 19.8 12.5 66.9 20.7 7.3 12.8 29.9 SFN YWHAS ENSG00000175793 Stratifin P31947 1 26863149-26864456 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 2461.5;skin 1: 1219.1;vagina: 692.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 7750.0;Basal prostatic cells: 2119.7;Squamous epithelial cells: 3587.1;Suprabasal keratinocytes: 10714.0;Urothelial cells: 2780.0" "Cancer enhanced" "Detected in all" "cervical cancer: 1510.8;head and neck cancer: 2526.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 17 "basophil: 5.9" "Lineage enriched" "Detected in single" 17 "granulocytes: 5.9" "Cell line enhanced" "Detected in many" "A-431: 770.8;HaCaT: 1181.6;HBEC3-KT: 1819.0;hTCEpi: 1196.7" "Low region specificity" "Detected in many" "CAB006268, HPA011105, CAB040552" Enhanced Supported Cytosol "Secreted in other tissues" NA Yes 29000000 "Cluster 34: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" Cytosol "CAB006268: AB_425459, CAB040552: , HPA011105: AB_1844339" "unprognostic (5.70e-2)" "unprognostic (1.26e-1)" "unprognostic (8.37e-2)" "prognostic favorable (1.92e-4)" "unprognostic (1.26e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (5.68e-5)" "unprognostic (1.71e-2)" "unprognostic (2.99e-1)" "unprognostic (3.96e-1)" "prognostic unfavorable (6.01e-4)" "unprognostic (3.83e-1)" "prognostic unfavorable (7.45e-6)" "unprognostic (7.90e-3)" "unprognostic (3.25e-1)" "unprognostic (8.12e-2)" "unprognostic (2.06e-2)" 3.1 0.8 1.9 11.6 1.8 2.0 29.1 1.8 9.5 350.2 0.4 95.4 48.8 8.0 0.7 2461.5 2.2 21.4 1.3 1.9 1.6 16.0 3.7 56.1 0.2 9.0 4.4 0.9 2.2 0.1 2.7 1.6 4.3 77.2 32.5 0.6 332.8 3.2 5.0 1219.1 40.8 3.3 1.2 0.9 66.6 0.7 5.2 22.1 2.0 0.1 147.9 167.6 692.0 2.3 770.8 126.9 0.1 1.1 0.3 0.1 37.2 0.5 0.0 0.1 0.3 46.6 393.6 6.7 32.2 0.2 0.6 1181.6 0.3 1819.0 0.0 183.4 5.4 0.9 119.6 138.4 0.1 0.4 1.4 0.4 1196.7 0.6 310.1 0.2 0.2 0.7 1.8 4.5 0.1 163.8 0.7 0.3 2.3 132.6 208.7 0.5 0.4 43.1 281.3 173.9 0.7 0.7 181.2 31.9 1.8 2.9 83.6 1.5 0.5 0.5 337.2 0.3 4.9 1.0 5.8 3.8 1.5 0.7 0.7 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.9 1.8 1.8 9.5 1.9 1.6 9.0 4.4 4.3 1.2 5.2 2.3 1.6 179.5 162.2 0.0 5.0 7750.0 2119.7 1374.7 1714.2 0.0 72.6 119.9 0.8 24.3 285.6 16.5 0.0 18.6 0.7 972.0 3.9 48.8 0.0 138.0 20.1 45.3 67.4 0.0 0.0 76.2 59.9 46.2 221.2 251.8 32.3 0.0 0.4 4.5 1.9 0.0 0.1 140.7 114.0 0.6 479.7 0.0 0.0 9.7 533.6 0.0 1.0 0.0 0.0 0.0 0.1 524.8 933.0 0.0 21.2 1030.2 318.5 0.6 158.2 0.0 0.0 0.7 55.2 0.0 0.6 3587.1 10714.0 6.0 23.4 0.1 292.4 2780.0 SGCB "A3b, LGMD2E, SGC" ENSG00000163069 "Sarcoglycan beta" Q16585 4 52020706-52038299 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 105.7" "Cell type enhanced" "Detected in many" "Late spermatids: 203.7" "Cancer enhanced" "Detected in all" "glioma: 56.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 104.7" "Low region specificity" "Detected in all" "HPA011422, HPA058656" Enhanced Approved Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA011422: AB_1856795, HPA058656: AB_2683790" "unprognostic (1.03e-1)" "unprognostic (5.50e-2)" "unprognostic (1.03e-1)" "unprognostic (1.60e-3)" "unprognostic (9.80e-2)" "unprognostic (3.42e-2)" "unprognostic (3.57e-3)" "unprognostic (1.86e-2)" "unprognostic (2.84e-2)" "unprognostic (6.04e-2)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "prognostic favorable (5.53e-6)" "unprognostic (3.74e-2)" "unprognostic (1.03e-1)" "unprognostic (1.97e-2)" "prognostic unfavorable (7.61e-4)" 32.7 21.6 27.1 9.5 30.3 0.5 14.7 28.0 32.2 23.4 21.4 32.9 13.1 28.1 11.1 21.9 20.5 19.5 57.2 25.3 27.7 35.0 10.8 15.2 6.1 29.7 28.4 20.1 6.5 47.0 13.9 24.2 30.3 25.0 16.2 16.6 13.5 27.2 105.7 7.2 14.9 37.3 29.0 11.1 14.0 16.0 28.3 5.6 9.2 81.3 4.5 20.4 15.7 33.4 11.4 13.7 27.8 10.6 104.7 78.5 10.1 62.8 79.9 34.5 36.2 3.7 14.9 3.0 11.8 82.9 53.5 5.5 20.9 23.1 36.7 18.8 7.8 0.2 11.8 6.8 42.8 6.8 3.6 86.8 15.9 29.9 17.3 89.8 46.1 10.7 0.1 0.1 74.5 4.4 15.1 0.1 10.0 4.6 20.4 0.0 14.8 0.2 29.2 3.8 16.2 28.4 39.9 1.9 14.1 31.0 5.2 4.1 47.0 50.8 17.0 24.1 56.6 14.9 20.4 5.5 37.5 2.4 59.7 0.3 1.0 0.0 2.1 0.5 2.1 2.6 2.5 2.3 0.5 2.3 1.7 2.2 0.5 0.3 0.4 1.0 4.2 1.0 27.1 30.3 28.0 32.2 25.3 27.7 29.7 28.4 30.3 29.0 28.3 33.4 38.9 32.1 13.1 15.3 6.6 13.4 25.8 70.2 9.6 22.0 8.6 19.7 88.8 25.8 19.6 12.9 6.2 5.7 2.8 15.6 1.9 28.7 61.1 32.6 48.1 27.2 16.3 0.0 17.3 51.8 49.8 64.6 12.8 29.7 2.5 16.7 36.0 15.7 2.8 28.6 21.2 4.2 8.2 2.1 8.7 203.7 38.8 2.7 26.6 24.4 1.9 23.6 1.0 38.7 38.1 53.8 6.0 91.4 4.6 11.7 32.6 64.6 20.4 16.5 46.0 102.8 59.8 12.2 17.4 8.0 10.5 6.3 7.3 14.2 15.1 13.5 SH2B2 APS ENSG00000160999 "SH2B adaptor protein 2" 7 102285091-102321711 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 37.3" "Cell type enhanced" "Detected in many" "B-cells: 31.4;Extravillous trophoblasts: 67.0;Plasma cells: 30.0;Syncytiotrophoblasts: 58.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 3.4" "Group enriched" "Detected in many" 6 "B-cells: 3.4;granulocytes: 1.8;monocytes: 1.6" "Cell line enhanced" "Detected in many" "Daudi: 64.2;Karpas-707: 60.7;RPMI-8226: 46.7;U-266/70: 56.1;U-266/84: 106.7;U-698: 88.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051131 Uncertain Approved Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 57: B-cells - Immune response" Cytosol "HPA051131: AB_2681354" "unprognostic (2.01e-2)" "unprognostic (4.00e-1)" "unprognostic (2.43e-2)" "unprognostic (7.32e-3)" "unprognostic (4.65e-2)" "unprognostic (1.07e-1)" "unprognostic (4.95e-3)" "unprognostic (2.42e-1)" "unprognostic (3.65e-1)" "unprognostic (1.29e-1)" "unprognostic (8.29e-2)" "unprognostic (2.00e-2)" "prognostic unfavorable (6.99e-7)" "unprognostic (1.25e-1)" "unprognostic (2.60e-1)" "unprognostic (2.02e-3)" "unprognostic (3.42e-2)" 5.4 1.8 6.3 5.8 4.9 3.6 3.6 4.3 5.3 4.6 1.3 2.6 2.2 4.5 0.3 1.9 4.6 1.5 2.2 3.9 9.3 6.0 1.8 5.7 10.7 10.6 11.2 1.9 1.9 1.0 3.0 1.8 7.0 4.4 0.5 0.8 2.8 0.7 37.3 3.6 5.5 0.9 7.1 14.5 2.4 3.4 10.4 0.8 4.5 13.8 5.5 4.0 3.4 3.5 3.7 2.8 3.0 6.6 0.7 0.3 27.6 1.3 0.5 0.8 0.6 0.8 0.6 64.2 6.4 0.5 2.8 3.7 0.7 0.9 0.3 8.1 2.8 0.0 1.7 0.6 0.6 0.5 2.2 0.6 0.9 0.5 0.2 1.1 0.2 1.6 0.4 60.7 1.3 6.9 0.3 11.5 7.0 2.3 11.5 8.1 3.3 46.7 2.1 1.0 3.2 11.4 2.3 5.6 1.6 2.3 1.0 8.4 0.2 1.0 6.2 11.0 1.3 56.1 106.7 88.3 3.9 2.3 1.5 0.0 0.3 0.0 0.0 1.6 0.0 0.6 0.0 0.0 0.3 3.4 0.0 0.0 1.8 0.0 0.6 0.0 0.0 0.0 6.3 4.9 4.3 5.3 3.9 9.3 10.6 11.2 7.0 7.1 10.4 3.5 5.6 0.0 0.0 6.2 31.4 2.5 2.5 0.0 1.8 6.8 3.4 2.9 1.1 1.5 0.0 0.0 0.0 9.3 2.9 0.8 0.0 0.2 0.4 3.8 2.4 7.3 1.8 0.4 2.2 0.0 67.0 2.0 1.1 5.4 0.0 1.0 2.2 0.8 7.8 5.0 4.8 0.6 0.0 14.1 17.6 2.0 0.6 15.1 7.2 2.8 6.0 9.2 1.0 1.0 0.5 0.1 0.5 0.4 30.0 5.7 0.1 13.0 0.0 1.4 0.0 6.6 2.0 1.1 15.8 0.6 1.6 58.1 1.3 0.4 1.3 2.2 SH2D1A "DSHP, EBVS, IMD5, LYP, MTCP1, SAP, XLP, XLPD" ENSG00000183918 "SH2 domain containing 1A" O60880 X 124227868-124373197 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "lymphoid tissue: 262.5" "Group enriched" "Detected in some" 7 "dendritic cells: 77.6;NK-cells: 138.0;T-cells: 108.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 54 "gdT-cell: 120.2;MAIT T-cell: 162.9;memory CD4 T-cell: 90.4;memory CD8 T-cell: 175.8;naive CD4 T-cell: 91.2;naive CD8 T-cell: 108.3;NK-cell: 162.2;T-reg: 125.3" "Group enriched" "Detected in many" 70 "NK-cells: 162.2;T-cells: 175.8" "Group enriched" "Detected in some" 6 "HDLM-2: 101.1;JURKAT: 193.0;Karpas-707: 201.3;MOLT-4: 257.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA072265 Approved Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA072265: " "prognostic favorable (2.03e-4)" "unprognostic (1.18e-3)" "unprognostic (4.35e-3)" "unprognostic (9.66e-5)" "unprognostic (1.60e-1)" "unprognostic (1.86e-3)" "unprognostic (9.25e-3)" "unprognostic (3.34e-2)" "unprognostic (1.88e-2)" "unprognostic (2.80e-3)" "unprognostic (9.33e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.94e-6)" "unprognostic (1.27e-1)" "unprognostic (9.00e-2)" "unprognostic (2.36e-1)" "unprognostic (3.14e-3)" 1.4 1.1 0.0 10.8 0.1 5.4 1.2 0.1 0.2 0.9 0.1 1.6 1.5 0.6 0.6 1.1 0.5 4.1 0.3 0.1 0.1 0.4 2.8 3.2 38.4 0.2 0.1 0.4 0.2 0.2 0.2 0.3 0.1 1.1 1.5 0.0 1.3 0.3 0.3 0.4 2.5 0.6 0.2 14.7 2.7 0.2 0.1 262.5 0.7 1.2 16.6 5.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 15.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 101.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 193.0 0.0 201.3 0.0 0.0 257.2 4.6 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 32.7 33.3 0.0 0.2 0.0 0.0 1.4 0.6 0.1 120.2 0.5 162.9 1.1 90.4 175.8 0.5 0.2 91.2 108.3 2.4 162.2 1.2 0.8 125.3 91.3 0.0 0.1 0.1 0.2 0.1 0.1 0.2 0.1 0.1 0.2 0.1 0.1 1.1 3.2 4.7 0.0 3.0 1.5 0.1 0.0 0.0 0.0 0.7 0.8 0.2 1.5 0.0 0.0 0.0 0.1 77.6 0.0 0.0 0.0 0.0 0.5 0.2 0.7 0.0 7.4 0.1 0.0 0.0 2.0 1.1 0.2 3.8 0.0 3.6 0.9 0.1 0.0 0.0 0.0 0.0 5.6 4.4 0.0 0.0 4.3 5.4 0.0 2.3 0.0 138.0 0.5 0.2 0.0 0.0 0.0 14.1 0.2 0.0 0.5 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.2 1.0 0.1 108.9 0.0 0.0 0.0 SH2D3C NSP3 ENSG00000095370 "SH2 domain containing 3C" Q8N5H7 9 127738317-127778710 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 52.6;dendritic cells: 29.7;Endothelial cells: 52.2;Hepatic stellate cells: 41.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 53.3;HUVEC TERT2: 60.0;REH: 60.7;RPMI-8226: 46.1;TIME: 50.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047586 Enhanced Supported Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA047586: AB_2680093" "unprognostic (8.33e-2)" "unprognostic (4.77e-3)" "unprognostic (3.28e-2)" "prognostic favorable (9.47e-4)" "unprognostic (5.23e-2)" "prognostic favorable (1.98e-4)" "unprognostic (3.75e-2)" "unprognostic (2.22e-1)" "unprognostic (1.41e-1)" "unprognostic (1.03e-1)" "unprognostic (2.58e-3)" "unprognostic (1.61e-1)" "unprognostic (1.88e-3)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (1.18e-1)" "unprognostic (5.28e-2)" 27.3 7.6 11.2 15.9 10.5 11.2 24.9 11.7 13.2 12.2 2.8 7.6 4.5 15.8 1.2 5.8 12.6 9.2 44.7 10.7 9.6 19.9 4.7 52.2 25.8 8.6 7.5 5.0 4.8 3.9 7.1 15.8 8.4 8.5 1.8 0.8 6.8 3.5 14.6 7.4 15.1 7.3 8.1 47.2 7.3 5.1 8.9 27.8 22.9 11.4 10.5 10.9 9.4 8.0 0.1 0.2 0.9 0.2 0.8 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 19.5 1.1 0.0 1.1 0.7 0.0 0.0 0.0 15.6 0.3 7.3 0.1 0.0 0.3 5.6 53.3 0.3 0.2 0.3 0.1 0.0 60.0 11.6 0.2 20.6 0.0 0.1 5.1 16.8 0.8 0.0 0.0 60.7 0.9 46.1 0.0 0.0 14.5 4.4 0.3 0.1 0.0 1.4 0.1 9.6 50.1 0.0 1.2 0.1 0.1 20.3 22.2 20.3 0.4 4.8 0.0 34.0 29.9 37.8 32.3 94.7 26.4 26.2 18.8 30.4 32.8 29.5 16.6 17.5 82.2 34.6 124.8 59.8 21.6 34.2 11.2 10.5 11.7 13.2 10.7 9.6 8.6 7.5 8.4 8.1 8.9 8.0 52.6 3.2 5.8 0.7 15.9 1.3 0.3 1.9 0.6 3.2 1.1 1.7 10.5 2.8 0.9 0.0 0.0 0.3 29.7 0.0 0.0 0.5 13.8 2.2 2.8 52.2 4.2 3.6 10.8 0.0 0.2 3.1 2.0 0.8 11.4 0.0 41.7 0.7 6.0 3.3 10.7 0.3 0.0 6.0 3.7 16.3 1.2 10.7 1.8 23.4 13.4 3.6 21.6 3.0 0.7 0.1 0.0 0.7 7.6 0.1 0.0 0.1 0.8 2.4 6.6 1.2 12.5 1.8 1.5 0.9 0.4 0.7 15.5 2.0 0.1 0.2 SH2D4A "FLJ20967, PPP1R38, SH2A" ENSG00000104611 "SH2 domain containing 4A" Q9H788 8 19313693-19396218 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 87.7;Pancreatic endocrine cells: 99.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.8" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 181.7;OE19: 102.5;U-2197: 130.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001871, HPA001919" Enhanced Enhanced Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA001871: AB_1079949, HPA001919: AB_1079947" "unprognostic (9.08e-2)" "unprognostic (8.40e-3)" "unprognostic (4.04e-3)" "unprognostic (2.72e-3)" "unprognostic (3.51e-2)" "unprognostic (4.07e-3)" "unprognostic (2.25e-1)" "unprognostic (2.68e-1)" "unprognostic (1.67e-1)" "unprognostic (2.70e-2)" "unprognostic (8.84e-3)" "unprognostic (2.81e-1)" "prognostic favorable (6.02e-8)" "unprognostic (1.67e-2)" "unprognostic (2.18e-1)" "unprognostic (3.51e-3)" "unprognostic (4.11e-2)" 5.0 8.8 1.6 4.1 1.4 0.1 6.2 1.2 2.0 13.6 1.9 13.6 12.7 4.0 1.7 20.4 9.1 11.1 3.1 1.6 1.5 12.6 39.1 15.8 1.0 1.6 1.6 36.9 13.1 18.2 1.4 17.7 1.9 7.4 10.8 9.6 24.0 10.1 0.6 7.2 12.6 2.0 1.3 3.3 29.9 2.2 1.5 1.3 16.8 1.6 7.4 18.3 10.5 2.0 60.5 67.3 0.2 0.1 6.5 8.0 44.9 73.9 36.6 70.7 68.3 55.7 53.4 0.0 17.4 181.7 11.2 30.5 2.7 20.0 73.6 0.2 1.0 0.0 40.7 8.6 38.3 1.6 0.3 7.8 24.5 48.4 8.8 42.5 0.3 0.0 0.1 0.1 12.0 27.2 0.1 0.7 15.8 102.5 25.4 0.1 0.0 19.5 19.5 62.6 4.1 0.1 66.0 70.6 0.2 10.4 13.3 5.3 1.2 22.9 0.1 130.8 22.4 0.0 0.7 0.2 23.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.2 0.2 0.0 1.8 0.1 0.0 0.0 0.1 0.0 1.6 1.4 1.2 2.0 1.6 1.5 1.6 1.6 1.9 1.3 1.5 2.0 8.5 64.1 33.9 6.5 0.9 1.5 15.0 22.2 5.2 2.2 9.4 5.6 2.0 34.3 26.2 46.0 27.1 87.7 0.3 20.1 43.0 50.3 25.3 30.9 6.0 5.4 3.0 0.0 1.5 67.0 69.4 11.7 67.8 34.4 1.3 43.3 2.5 45.5 37.7 1.7 1.0 24.8 54.9 8.5 1.6 53.5 6.2 6.3 0.0 1.9 0.6 3.5 0.0 11.1 0.3 99.1 8.3 11.3 0.4 14.6 20.5 10.9 46.9 36.2 19.7 3.0 6.5 0.5 2.8 31.9 2.6 30.6 1.0 52.0 26.3 31.2 SH2D5 ENSG00000189410 "SH2 domain containing 5" Q6ZV89 1 20719731-20732837 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 21.7;testis: 8.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 4.8;Excitatory neurons: 9.9;Inhibitory neurons: 5.3;Syncytiotrophoblasts: 5.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.6" "Group enriched" "Detected in many" 8 "amygdala: 6.4;basal ganglia: 21.7;cerebral cortex: 11.3;hippocampal formation: 6.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 47.0;hTERT-HME1: 59.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA030182 Approved Cytosol NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA030182: AB_10670431" "unprognostic (2.32e-1)" "unprognostic (2.80e-2)" "unprognostic (3.85e-2)" "unprognostic (5.37e-3)" "unprognostic (1.20e-4)" "unprognostic (4.41e-2)" "unprognostic (1.80e-6)" "unprognostic (1.11e-3)" "unprognostic (2.07e-1)" "unprognostic (9.43e-3)" "unprognostic (1.21e-2)" "unprognostic (1.45e-1)" "unprognostic (1.77e-2)" "unprognostic (2.55e-2)" "unprognostic (2.34e-1)" "unprognostic (1.14e-1)" "unprognostic (1.51e-2)" 0.1 0.2 6.4 0.5 21.7 0.0 0.0 0.0 11.3 1.0 0.0 0.3 0.4 0.6 0.0 0.2 0.2 0.1 0.2 6.7 0.0 0.6 0.2 0.1 0.0 0.0 0.0 0.8 0.0 0.2 0.3 3.5 0.0 0.6 0.0 0.4 0.1 0.7 0.0 0.2 0.1 0.4 0.0 0.0 0.2 8.0 1.3 0.0 0.7 0.0 0.1 0.2 0.3 0.0 18.8 7.4 1.6 0.0 0.0 0.0 0.2 9.0 11.8 8.3 5.6 3.2 2.9 0.0 2.2 2.7 18.1 0.8 6.1 47.0 3.5 0.1 3.4 0.0 1.1 2.2 6.3 0.0 0.1 0.5 10.0 15.6 59.0 3.0 0.1 1.5 0.0 0.0 3.7 1.7 1.0 0.0 2.9 1.0 9.4 0.2 0.3 0.4 8.2 1.1 2.8 0.4 0.6 0.2 2.8 1.3 0.0 0.0 0.0 9.6 17.6 14.7 4.2 0.0 0.1 0.8 3.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 21.7 0.0 11.3 6.7 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 1.3 0.0 4.8 1.4 0.7 0.0 1.8 0.2 0.1 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.4 0.1 0.1 0.1 0.0 0.0 9.9 0.2 0.1 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 5.3 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 1.9 0.0 0.0 0.0 1.0 0.8 1.9 0.0 0.0 0.0 1.6 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.9 0.8 0.0 2.3 5.1 0.1 0.0 0.1 0.3 SH3BP1 ARHGAP43 ENSG00000100092 "SH3 domain binding protein 1" Q9Y3L3 22 37634654-37656117 "Metabolic proteins, Predicted intracellular proteins" Phagocytosis "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 37.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 43.5;HMC-1: 45.4;NB-4: 44.7" "Low region specificity" "Detected in all" HPA000757 Supported Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA000757: AB_1079951" "unprognostic (7.81e-3)" "unprognostic (7.91e-3)" "unprognostic (3.42e-1)" "unprognostic (2.62e-2)" "unprognostic (5.38e-2)" "unprognostic (2.40e-1)" "prognostic unfavorable (9.55e-4)" "unprognostic (1.39e-1)" "unprognostic (3.08e-1)" "unprognostic (1.89e-1)" "unprognostic (2.59e-2)" "unprognostic (4.78e-1)" "prognostic unfavorable (3.48e-7)" "prognostic favorable (3.39e-4)" "unprognostic (1.74e-1)" "unprognostic (5.37e-2)" "unprognostic (8.48e-3)" 4.2 3.6 3.4 14.2 3.4 14.4 3.4 3.7 6.2 12.2 2.7 19.4 18.1 3.2 0.7 37.7 4.0 2.1 2.0 4.1 4.5 3.2 2.6 8.8 12.1 6.0 3.9 3.4 2.8 2.2 2.1 5.1 4.7 7.6 4.5 0.2 9.3 2.0 0.7 27.0 20.9 2.0 4.8 27.0 4.3 5.7 4.7 8.2 2.5 0.5 7.7 10.5 21.1 5.7 20.1 1.0 3.9 3.4 0.9 3.9 28.6 3.8 6.4 6.3 7.0 5.9 2.3 12.6 2.7 2.4 2.0 43.5 2.0 26.0 2.6 36.9 13.7 18.5 0.6 8.6 3.3 25.9 45.4 4.9 6.3 7.9 0.9 5.2 1.0 6.3 6.4 4.8 0.6 12.7 3.0 44.7 7.6 13.7 3.8 15.7 3.2 11.0 0.8 22.2 3.8 10.1 1.0 5.3 17.9 3.9 6.7 22.1 1.3 2.3 10.8 0.5 0.2 29.9 10.2 9.0 3.2 26.4 13.0 1.8 1.4 4.6 1.0 1.8 1.0 0.3 1.1 1.1 0.7 0.1 0.6 1.4 0.9 0.8 3.7 1.2 1.1 0.6 3.4 3.4 3.7 6.2 4.1 4.5 6.0 3.9 4.7 4.8 4.7 5.7 1.2 0.0 7.2 0.7 23.7 19.1 22.2 42.5 23.3 0.3 3.3 4.1 1.2 4.3 8.0 0.0 2.1 47.5 36.1 55.0 0.0 3.0 0.4 0.6 4.3 1.7 4.2 7.8 5.6 4.7 43.9 6.0 11.2 1.3 14.0 3.4 4.2 0.5 48.3 8.4 0.8 29.9 12.2 33.3 19.0 0.1 5.0 45.6 5.4 2.8 36.0 3.0 53.5 5.0 0.9 2.0 46.8 1.9 20.9 29.6 41.9 0.3 11.4 0.5 0.0 0.9 3.6 3.4 6.0 23.6 15.3 37.5 52.7 5.0 23.6 42.0 SH3GL1 "CNSA1, EEN, MGC111371, SH3D2B, SH3P8" ENSG00000141985 "SH3 domain containing GRB2 like 1, endophilin A2" Q99961 19 4360370-4400547 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" Endocytosis "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 153.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021485 Approved Enhanced Cytosol NA NA 390000 "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "HPA021485: AB_1856816" "unprognostic (1.32e-1)" "prognostic favorable (1.50e-4)" "unprognostic (6.85e-2)" "prognostic favorable (1.86e-4)" "unprognostic (1.84e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.10e-4)" "unprognostic (1.92e-2)" "unprognostic (1.21e-1)" "unprognostic (1.42e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (9.36e-8)" "unprognostic (5.48e-3)" "unprognostic (2.45e-1)" "unprognostic (1.02e-3)" "unprognostic (4.10e-2)" 61.1 64.7 25.0 29.4 28.8 54.4 50.0 32.8 38.1 69.8 24.2 41.3 40.9 45.1 8.2 175.8 43.9 25.4 37.6 34.4 20.5 39.2 57.4 43.8 22.8 24.8 22.5 49.0 41.8 10.8 46.8 38.9 23.8 48.8 9.2 7.0 51.8 24.0 21.2 119.8 43.7 20.8 21.1 46.8 35.9 28.1 24.7 16.8 37.1 10.1 19.8 53.0 91.6 28.0 111.3 49.2 50.0 66.8 57.4 89.0 92.2 94.2 80.3 82.2 81.1 77.4 56.8 24.9 39.0 94.1 39.8 89.5 35.6 103.7 21.9 33.1 59.8 30.0 66.5 102.7 82.6 27.2 32.6 75.0 70.9 69.4 42.4 40.6 97.8 23.7 78.9 55.1 67.1 92.6 26.5 28.4 126.0 40.4 54.3 20.8 69.8 43.6 65.8 96.4 49.1 75.7 83.3 81.9 59.3 23.5 56.5 42.5 149.3 78.6 57.1 166.7 97.2 34.8 23.2 26.7 112.9 70.0 110.4 0.8 2.3 3.1 2.7 1.1 2.6 3.7 4.0 3.9 3.0 2.7 2.2 2.5 5.6 2.3 3.4 3.8 4.1 2.3 25.0 28.8 32.8 38.1 34.4 20.5 24.8 22.5 23.8 21.1 24.7 28.0 31.6 9.6 21.5 11.8 15.2 60.8 41.0 43.2 19.4 17.1 17.1 15.7 3.6 11.5 25.1 9.2 6.2 41.2 14.7 23.6 13.7 32.1 7.2 17.9 33.8 30.7 10.2 30.7 23.4 29.3 153.7 37.5 19.9 29.5 9.5 23.4 32.9 27.3 51.5 10.1 14.0 18.6 20.3 19.4 51.8 6.7 32.6 22.3 23.2 14.0 14.7 20.3 15.5 12.5 10.3 50.4 17.0 24.0 16.4 38.0 61.6 22.9 15.4 8.7 13.1 17.2 29.3 15.7 11.5 36.8 85.8 44.2 15.1 50.1 19.8 67.1 SH3GLB1 "Bif-1, CGI-61, KIAA0491, PPP1R70" ENSG00000097033 "SH3 domain containing GRB2 like, endophilin B1" Q9Y371 1 86704570-86748184 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Autophagy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 634.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 301.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004650, HPA015608, HPA019900" Enhanced Supported Cytosol NA NA 28000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "CAB004650: AB_425966, HPA015608: AB_1845355, HPA019900: AB_1845356" "unprognostic (1.72e-2)" "unprognostic (1.76e-1)" "unprognostic (5.52e-2)" "unprognostic (9.94e-2)" "unprognostic (3.42e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (2.90e-5)" "unprognostic (8.34e-2)" "unprognostic (1.75e-1)" "unprognostic (4.29e-1)" "prognostic unfavorable (2.53e-4)" "unprognostic (1.56e-1)" "unprognostic (4.04e-3)" "unprognostic (7.70e-2)" "unprognostic (2.65e-1)" "unprognostic (1.88e-2)" "unprognostic (1.69e-1)" 106.5 38.1 20.5 55.3 22.5 66.2 56.1 21.0 25.4 39.2 15.7 53.7 48.4 35.9 31.0 79.4 27.9 47.0 72.8 19.2 23.7 40.4 45.0 49.0 40.9 25.3 19.7 24.2 64.0 41.3 30.3 57.5 24.4 34.3 57.9 39.0 56.4 36.1 172.0 35.8 47.0 50.3 23.4 46.5 36.3 109.5 21.0 34.1 38.6 98.4 51.9 63.8 41.8 27.4 78.1 28.1 44.2 40.4 180.1 155.1 72.2 115.1 114.5 106.8 112.3 81.4 63.3 39.7 72.0 143.5 132.9 44.5 39.4 75.0 101.2 86.1 28.1 94.7 39.2 87.1 108.7 51.5 92.4 111.8 85.5 118.3 128.7 114.5 171.4 41.7 36.0 108.5 145.1 23.1 46.7 32.7 43.0 56.8 47.6 53.1 184.6 29.7 92.3 132.2 47.9 34.7 64.8 82.4 140.8 65.2 32.7 51.8 151.4 102.2 61.9 129.3 96.5 56.8 56.3 58.6 50.8 52.1 63.5 153.0 59.0 66.5 43.0 64.5 42.4 36.8 40.2 43.8 45.5 35.3 19.1 34.3 301.4 62.4 77.0 43.8 65.4 49.5 20.5 22.5 21.0 25.4 19.2 23.7 25.3 19.7 24.4 23.4 21.0 27.4 192.0 83.3 65.6 39.2 75.0 89.6 119.5 124.1 44.3 31.2 96.9 69.1 157.0 60.1 104.0 55.2 52.1 84.3 145.7 182.0 86.1 145.2 634.6 86.3 104.5 135.4 86.6 64.4 49.9 169.8 203.4 99.7 45.9 110.0 113.5 61.0 157.1 79.4 143.7 16.8 50.5 130.3 128.1 149.2 99.4 236.9 70.2 116.0 81.8 40.3 163.7 71.9 124.6 46.8 65.2 201.7 173.4 85.0 123.9 103.4 108.8 134.0 90.2 55.4 78.9 146.7 111.7 403.5 86.3 100.6 118.1 101.9 90.4 57.1 87.4 199.8 SH3KBP1 CIN85 ENSG00000147010 "SH3 domain containing kinase binding protein 1" Q96B97 X 19533977-19887600 "Disease related genes, Predicted intracellular proteins" "Apoptosis, Endocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 207.8;monocytes: 289.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003351, HPA003355, CAB021892" Enhanced Supported Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" Cytosol "CAB021892: , HPA003351: AB_1079956, HPA003355: AB_1079954" "unprognostic (1.17e-2)" "unprognostic (1.33e-1)" "unprognostic (9.48e-2)" "unprognostic (4.65e-3)" "unprognostic (1.62e-1)" "unprognostic (2.88e-2)" "unprognostic (6.47e-2)" "unprognostic (9.91e-2)" "unprognostic (9.75e-2)" "unprognostic (1.76e-3)" "unprognostic (5.96e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (2.10e-6)" "unprognostic (4.00e-1)" "unprognostic (1.54e-1)" "unprognostic (3.94e-2)" "unprognostic (4.92e-2)" 45.1 11.0 17.1 45.5 16.8 68.6 26.6 14.2 20.3 18.2 47.3 37.1 13.7 10.6 11.3 8.5 11.9 21.2 24.4 16.4 20.8 13.5 15.6 26.0 68.1 19.9 22.9 8.7 6.9 14.4 11.9 32.5 20.3 6.7 35.3 5.1 10.4 7.4 13.0 24.0 18.4 14.8 18.5 37.0 18.9 5.7 26.0 55.0 20.5 32.4 68.7 17.7 11.2 27.1 52.5 54.3 8.4 19.4 41.6 80.0 44.2 46.4 67.4 23.3 37.2 37.2 105.6 97.4 47.6 67.5 67.0 5.9 19.8 18.4 37.3 32.3 13.4 21.2 13.6 30.1 27.2 134.0 160.2 47.4 18.0 48.5 141.9 64.6 35.4 67.6 8.0 114.2 59.7 23.5 80.4 135.4 14.8 63.1 71.2 49.1 82.0 9.1 27.1 10.6 6.0 6.2 43.2 5.6 65.3 53.8 5.4 155.2 113.6 40.6 34.9 52.2 51.9 165.6 119.0 86.0 86.5 109.4 183.5 49.2 104.7 171.1 180.2 77.7 140.4 55.4 174.2 187.8 132.6 50.3 143.3 142.5 210.0 76.5 96.9 148.4 224.1 195.9 17.1 16.8 14.2 20.3 16.4 20.8 19.9 22.9 20.3 18.5 26.0 27.1 40.3 16.0 54.4 5.5 75.6 12.0 3.5 7.5 5.2 5.1 5.4 6.2 78.1 11.5 25.0 9.2 16.7 26.2 174.3 207.8 1.9 8.3 0.7 6.3 28.5 26.5 50.8 23.3 72.3 18.9 39.3 56.9 23.4 8.3 96.6 5.9 27.8 17.6 55.8 8.4 126.3 34.4 10.2 87.4 102.1 1.9 52.8 113.0 33.8 108.7 289.2 0.1 175.1 87.0 145.9 48.0 153.3 38.4 63.5 3.5 26.4 40.3 20.1 2.8 59.2 12.1 72.2 24.3 22.7 1.9 10.9 22.6 138.7 26.7 59.4 7.7 SHC1 "p66, SHC, ShcA" ENSG00000160691 "SHC adaptor protein 1" P29353 1 154962298-154974395 "Predicted intracellular proteins, RAS pathway related proteins" "Angiogenesis, Growth regulation, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001844, CAB005374, CAB016305" Supported Enhanced Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB005374: AB_632395, CAB016305: AB_628249, HPA001844: AB_1856826" "unprognostic (4.12e-2)" "prognostic unfavorable (6.74e-4)" "unprognostic (1.10e-2)" "unprognostic (3.77e-2)" "unprognostic (6.40e-2)" "unprognostic (4.08e-3)" "unprognostic (2.94e-3)" "prognostic unfavorable (1.92e-4)" "unprognostic (9.13e-2)" "unprognostic (1.66e-1)" "unprognostic (1.38e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (2.22e-16)" "unprognostic (7.19e-2)" "unprognostic (1.40e-1)" "unprognostic (9.21e-2)" "unprognostic (1.31e-1)" 147.4 103.8 30.9 90.3 29.8 72.8 126.7 28.9 32.0 91.3 32.2 71.8 72.1 86.0 53.7 73.5 87.5 88.8 67.0 28.0 33.2 71.4 94.5 106.3 50.6 36.2 32.6 70.7 57.7 61.8 120.5 77.0 36.4 85.0 70.9 16.5 58.7 70.2 63.3 59.2 73.0 107.6 32.7 72.8 69.7 23.3 39.5 47.4 86.4 56.2 52.8 96.6 83.2 30.4 110.8 223.7 168.9 272.3 180.6 359.3 88.6 393.5 355.3 223.6 168.7 80.2 258.5 59.3 314.0 476.4 64.1 92.9 45.5 389.6 200.2 72.7 25.0 152.0 185.7 143.9 471.1 49.3 164.8 538.3 452.4 279.4 344.0 605.8 497.7 25.0 68.2 461.3 473.8 90.0 56.8 29.8 147.9 89.7 94.2 51.1 56.1 122.6 107.1 82.5 21.6 582.1 234.8 130.2 126.3 293.3 189.8 102.9 595.6 349.6 217.5 75.1 209.0 206.6 146.2 101.7 341.4 65.9 463.5 32.4 36.7 58.0 39.0 47.7 38.7 22.4 30.7 34.6 38.0 20.8 24.6 22.4 29.2 23.2 48.2 17.5 24.6 39.1 30.9 29.8 28.9 32.0 28.0 33.2 36.2 32.6 36.4 32.7 39.5 30.4 86.0 28.9 23.6 7.5 14.1 35.7 54.5 76.5 40.9 5.1 24.0 30.6 2.2 20.0 19.1 5.5 6.2 25.7 13.1 44.1 7.9 29.0 0.7 14.7 58.8 88.0 12.6 16.0 5.4 28.0 58.0 36.3 26.0 26.9 17.7 16.8 77.8 44.5 23.3 25.2 3.7 24.5 34.6 22.3 25.1 2.7 23.0 19.5 17.8 2.8 14.5 8.7 11.3 4.5 2.1 34.0 27.6 34.6 29.1 53.5 34.4 9.6 13.0 7.4 19.7 22.7 35.7 3.8 4.9 26.9 36.4 60.9 16.2 24.5 22.4 50.0 SHC2 "SCK, SHCB, SLI" ENSG00000129946 "SHC adaptor protein 2" P98077 19 416583-460996 "Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 109.8" "Cell type enhanced" "Detected in many" "Adipocytes: 44.8;Hepatic stellate cells: 45.3;Hepatocytes: 56.7;Horizontal cells: 48.8;Oligodendrocyte precursor cells: 49.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 4.9;HHSteC: 5.6;SCLC-21H: 12.6;SH-SY5Y: 11.4" HPA006136 Approved Approved Cytosol NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 2: Hepatocytes - Metabolism" Cytosol "HPA006136: AB_1856827" "unprognostic (2.54e-2)" "unprognostic (4.87e-2)" "prognostic unfavorable (4.58e-4)" "unprognostic (6.40e-2)" "unprognostic (1.64e-1)" "unprognostic (1.50e-1)" "unprognostic (6.71e-2)" "unprognostic (9.37e-2)" "unprognostic (3.12e-1)" "unprognostic (1.36e-1)" "prognostic favorable (8.53e-4)" "unprognostic (4.45e-2)" "unprognostic (5.30e-2)" "unprognostic (1.99e-2)" "unprognostic (3.37e-1)" "unprognostic (8.86e-2)" "unprognostic (4.43e-2)" 16.0 19.9 21.4 1.6 17.9 0.1 17.5 9.5 31.1 28.2 5.1 22.0 6.3 24.2 2.0 5.0 23.6 10.9 18.2 17.0 32.0 12.2 63.8 17.3 1.7 24.9 18.6 14.1 109.8 7.0 48.0 7.6 19.6 32.6 0.4 1.2 24.5 5.1 5.0 10.2 10.6 2.9 15.7 26.6 21.4 9.6 29.0 0.3 32.7 1.2 0.3 10.0 11.7 19.0 0.0 0.1 0.4 0.1 0.0 0.0 0.6 0.5 2.5 0.3 0.0 0.0 0.4 0.0 4.9 0.0 1.2 0.4 1.1 0.0 0.0 1.1 1.7 0.0 0.0 2.8 5.6 0.0 1.9 0.3 0.0 0.0 0.0 2.6 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 1.9 0.0 12.6 11.4 0.0 0.0 0.0 2.3 0.3 2.0 0.0 0.5 3.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.4 17.9 9.5 31.1 17.0 32.0 24.9 18.6 19.6 15.7 29.0 19.0 44.8 6.4 8.8 33.3 0.5 1.9 2.0 0.8 0.6 11.4 11.3 10.0 9.9 18.6 1.5 0.0 2.1 0.1 0.9 0.1 0.0 25.2 2.5 2.8 4.9 16.6 8.4 2.7 22.1 38.5 0.1 9.5 3.6 4.1 0.0 15.4 45.3 56.7 0.9 48.8 33.1 3.5 6.1 5.3 1.7 7.2 9.0 0.4 8.8 15.0 1.0 29.5 0.0 49.8 28.4 21.1 0.1 11.3 0.2 11.3 0.3 0.4 1.4 3.5 0.0 4.5 13.8 14.7 11.0 0.4 3.1 0.0 1.0 1.6 0.9 3.7 SHC4 "RaLP, SHCD" ENSG00000185634 "SHC adaptor protein 4" Q6S5L8 15 48823741-48963919 "Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.6;testis: 10.5" "Cell type enhanced" "Detected in some" "Astrocytes: 16.6;Oligodendrocyte precursor cells: 30.7;Oligodendrocytes: 81.8" "Cancer enhanced" "Detected in some" "melanoma: 9.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AN3-CA: 10.0;SK-MEL-30: 19.1;WM-115: 16.5" "Low region specificity" "Detected in all" HPA074146 Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA074146: AB_2686667" "unprognostic (4.34e-3)" "unprognostic (1.01e-3)" "unprognostic (6.70e-2)" "unprognostic (1.06e-1)" "unprognostic (1.81e-1)" "unprognostic (1.05e-3)" "unprognostic (1.23e-2)" "unprognostic (3.47e-2)" "unprognostic (2.59e-1)" "unprognostic (2.21e-2)" "unprognostic (3.80e-2)" "unprognostic (3.71e-1)" "unprognostic (1.04e-5)" "unprognostic (9.84e-3)" "unprognostic (3.26e-2)" "unprognostic (3.49e-2)" "unprognostic (1.36e-2)" 0.5 0.9 12.7 1.0 21.0 0.1 1.6 15.8 18.9 1.0 6.7 2.8 0.3 0.4 0.9 0.5 1.0 1.4 3.3 14.0 14.3 0.3 0.1 0.3 0.3 18.3 16.9 0.5 0.2 0.1 1.0 0.4 19.0 0.7 0.5 0.9 2.1 1.3 0.9 0.6 0.8 0.7 13.6 0.2 0.7 10.5 17.8 0.3 0.3 1.2 0.1 0.4 0.9 36.6 0.0 0.4 1.0 10.0 0.4 1.3 0.0 1.5 2.9 0.6 1.2 0.0 0.3 0.1 2.6 0.6 0.1 0.0 0.2 0.4 0.8 2.2 0.1 0.6 0.0 0.0 1.1 0.0 0.2 1.9 0.0 1.3 0.1 1.3 0.1 1.0 0.0 0.2 1.4 1.9 0.4 0.2 0.1 0.0 3.7 0.2 2.7 0.3 2.1 0.4 0.5 0.8 0.2 0.1 19.1 0.9 0.0 0.1 0.0 0.9 0.5 0.6 1.0 0.9 0.1 0.1 0.8 0.5 16.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 21.0 15.8 18.9 14.0 14.3 18.3 16.9 19.0 13.6 17.8 36.6 0.2 0.0 0.0 16.6 0.0 0.3 0.0 2.3 0.0 0.6 1.6 6.7 2.5 0.0 2.8 0.0 0.0 0.7 0.0 0.0 0.0 6.4 2.5 0.4 0.4 0.2 0.0 0.0 9.3 0.0 0.2 1.8 0.0 0.3 0.0 0.0 0.7 0.0 0.1 1.7 6.1 0.0 0.0 0.0 0.4 4.5 1.2 0.1 7.2 1.0 0.0 2.7 0.0 30.7 81.8 0.2 0.0 3.4 0.0 0.0 0.0 0.1 2.6 1.0 0.0 0.5 0.3 6.0 6.3 0.1 0.3 0.8 0.3 0.5 0.0 0.0 SHISA7 ENSG00000187902 "Shisa family member 7" A6NL88 19 55428740-55443277 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 25.9" "Group enriched" "Detected in some" 6 "Erythroid cells: 13.5;Excitatory neurons: 19.4;Inhibitory neurons: 16.1;Oligodendrocyte precursor cells: 23.1;Oligodendrocytes: 16.1" "Cancer enriched" "Detected in single" 9 "glioma: 2.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HEL: 2.9;HMC-1: 2.8;THP-1: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058935 Uncertain Approved Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA058935: AB_2683857" "unprognostic (3.98e-2)" "unprognostic (5.81e-2)" "unprognostic (1.16e-1)" "unprognostic (1.28e-1)" "unprognostic (1.69e-1)" "unprognostic (1.78e-1)" "unprognostic (3.08e-1)" "unprognostic (4.40e-1)" "unprognostic (7.17e-2)" "unprognostic (2.11e-3)" "unprognostic (1.22e-2)" "unprognostic (6.87e-7)" "unprognostic (7.53e-3)" "unprognostic (2.82e-1)" "unprognostic (3.29e-4)" "unprognostic (4.04e-1)" 0.0 0.4 20.2 0.0 19.7 1.1 0.0 0.5 20.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.9 10.4 0.0 0.0 0.0 0.0 5.1 4.9 0.0 0.0 0.0 4.9 0.0 3.6 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 1.3 9.6 0.1 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.2 0.0 0.4 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.2 19.7 0.5 20.2 25.9 10.4 5.1 4.9 3.6 4.6 9.6 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.1 0.0 13.5 19.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 16.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 23.1 16.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SIGLEC8 "MGC59785, SAF2, SIGLEC-8, SIGLEC8L" ENSG00000105366 "Sialic acid binding Ig like lectin 8" Q9NYZ4 19 51450847-51458456 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.9;lymphoid tissue: 6.8" "Cell type enhanced" "Detected in some" "granulocytes: 44.9;Kupffer cells: 17.7;Microglial cells: 11.2" "Group enriched" "Detected in many" 4 "glioma: 7.2;renal cancer: 2.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 38 "eosinophil: 290.2" "Lineage enriched" "Detected in single" 719 "granulocytes: 290.2" "Cell line enriched" "Detected in some" 44 "HMC-1: 147.5" HPA012556 Uncertain Uncertain Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" Cytosol "HPA012556: AB_1856869" "unprognostic (1.27e-1)" "unprognostic (1.88e-4)" "unprognostic (1.28e-1)" "unprognostic (6.70e-2)" "unprognostic (2.97e-1)" "unprognostic (1.30e-2)" "unprognostic (7.84e-2)" "unprognostic (2.51e-2)" "unprognostic (2.72e-2)" "unprognostic (2.17e-1)" "unprognostic (1.10e-1)" "unprognostic (4.19e-1)" "unprognostic (8.62e-3)" "unprognostic (7.18e-2)" "unprognostic (6.02e-2)" "unprognostic (4.28e-3)" "unprognostic (3.29e-1)" 0.3 4.0 4.9 1.6 5.2 0.5 1.4 5.3 6.1 0.9 1.7 1.8 1.8 0.6 0.7 0.7 0.7 1.4 0.2 4.5 6.2 0.1 0.8 2.5 6.8 13.3 6.6 0.2 0.5 1.0 0.4 0.1 10.1 0.6 1.6 0.7 0.6 0.5 0.1 0.5 2.8 0.9 7.3 6.3 1.4 0.3 11.6 2.1 0.4 0.2 2.5 1.0 0.3 14.9 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 2.3 0.1 0.1 0.0 0.0 147.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.3 0.0 0.0 0.2 3.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.2 1.1 0.1 7.6 0.4 290.2 0.2 0.3 0.1 0.2 0.2 0.1 0.1 0.3 0.1 0.2 2.5 0.3 0.4 0.2 0.1 0.2 4.9 5.2 5.3 6.1 4.5 6.2 13.3 6.6 10.1 7.3 11.6 14.9 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 44.9 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 17.7 0.0 0.0 0.0 2.5 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 SLC12A7 "DKFZP434F076, KCC4" ENSG00000113504 "Solute carrier family 12 member 7" Q9Y666 5 1050384-1112063 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 77.3" "Cell type enriched" "Detected in many" 4 "Horizontal cells: 281.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "REH: 43.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041652 Approved Uncertain Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 14: REH - Unknown function" "Cluster 62: Horizontal cells - Visual perception" Cytosol "HPA041652: AB_10793971" "unprognostic (2.22e-2)" "unprognostic (1.56e-1)" "unprognostic (8.92e-2)" "unprognostic (2.86e-1)" "unprognostic (1.69e-2)" "unprognostic (8.72e-2)" "prognostic unfavorable (2.12e-6)" "unprognostic (1.67e-1)" "unprognostic (1.71e-3)" "unprognostic (4.40e-2)" "unprognostic (4.50e-2)" "unprognostic (3.44e-2)" "unprognostic (1.65e-3)" "unprognostic (1.17e-3)" "unprognostic (1.26e-1)" "unprognostic (3.93e-2)" "prognostic favorable (3.16e-5)" 21.1 14.6 8.9 7.2 8.0 4.0 18.8 7.2 10.4 15.8 12.3 24.1 24.0 13.8 1.0 8.0 16.6 12.0 77.3 7.9 12.0 45.1 72.4 23.1 5.7 8.0 10.7 12.3 27.6 4.4 20.5 2.9 8.0 20.7 5.4 5.5 18.9 3.0 6.3 15.8 31.9 3.3 6.8 34.9 28.1 29.9 9.4 7.8 24.7 3.1 2.2 14.5 10.8 7.1 3.8 10.0 5.5 17.3 0.8 0.9 8.7 0.2 1.1 0.8 0.0 24.5 6.4 0.0 20.0 0.3 6.8 7.6 4.6 6.1 0.0 23.0 6.1 4.8 13.4 8.6 12.2 0.0 10.4 1.8 0.8 0.0 1.8 0.3 5.5 2.2 7.6 0.2 0.0 12.0 14.8 0.1 11.9 14.4 16.3 43.9 24.0 20.5 6.5 14.8 3.1 3.8 5.6 0.1 6.0 3.3 9.7 2.7 4.8 0.0 5.7 0.0 0.0 0.3 0.0 2.5 0.0 0.6 2.8 0.2 1.8 0.0 1.1 2.7 1.2 0.6 1.1 1.3 2.1 0.6 1.2 1.2 0.0 1.4 3.8 0.9 1.1 1.3 8.9 8.0 7.2 10.4 7.9 12.0 8.0 10.7 8.0 6.8 9.4 7.1 21.3 9.6 15.2 8.5 7.3 7.0 6.3 8.9 6.8 25.3 18.4 13.8 35.8 31.5 13.6 29.5 2.1 0.2 14.2 42.0 1.9 23.5 0.4 40.9 11.0 27.9 13.2 19.1 0.3 18.1 0.4 11.6 39.8 63.4 8.2 16.6 11.7 34.5 19.8 281.0 0.5 19.4 18.3 28.0 19.8 1.9 3.7 29.0 16.0 14.0 9.1 5.2 5.2 1.5 0.0 28.8 35.8 5.7 5.3 15.7 27.3 23.2 23.1 3.6 19.7 5.2 8.4 1.0 3.4 3.5 6.8 0.3 9.8 5.4 19.3 15.2 SLC19A2 "THTR1, TRMA" ENSG00000117479 "Solute carrier family 19 member 2" O60779 1 169463909-169485944 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Deafness, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 124.1;tongue: 84.9" "Cell type enhanced" "Detected in many" "Skeletal myocytes: 84.5;Syncytiotrophoblasts: 156.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006119, HPA016599" Uncertain Approved Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA006119: AB_1079996, HPA016599: AB_1857005" "prognostic favorable (8.41e-4)" "unprognostic (8.82e-2)" "unprognostic (1.90e-1)" "unprognostic (3.29e-3)" "prognostic favorable (2.90e-4)" "unprognostic (4.45e-2)" "unprognostic (9.69e-2)" "unprognostic (1.45e-1)" "unprognostic (2.86e-2)" "unprognostic (1.60e-1)" "unprognostic (1.76e-1)" "unprognostic (1.65e-1)" "prognostic favorable (2.70e-5)" "unprognostic (1.08e-1)" "unprognostic (2.09e-1)" "unprognostic (3.60e-2)" "unprognostic (2.14e-2)" 42.2 17.8 3.0 8.3 3.1 8.7 20.9 5.1 4.2 10.5 9.3 11.8 3.5 8.6 6.1 11.3 21.3 25.8 31.2 4.0 3.6 13.0 37.1 19.5 2.6 4.9 3.7 20.5 22.2 24.8 19.0 18.1 4.0 10.5 4.3 7.5 12.5 3.8 124.1 16.5 11.4 6.1 3.7 2.8 19.2 7.8 4.2 4.1 15.7 84.9 2.8 18.1 12.9 3.5 7.4 5.1 11.4 9.0 34.4 12.7 25.0 5.8 4.3 4.6 6.5 20.9 7.6 6.5 6.4 3.9 8.5 7.7 13.9 8.5 5.1 18.8 13.0 6.2 16.7 19.3 18.7 15.8 5.9 15.0 12.2 7.4 18.8 6.4 7.0 11.3 25.3 4.1 7.9 5.0 8.2 7.1 25.8 14.1 7.7 0.0 24.6 7.5 12.2 15.5 9.9 13.3 8.0 13.6 29.2 12.8 8.5 10.1 5.8 5.5 7.7 6.9 11.4 5.6 5.6 2.1 8.1 6.0 7.4 0.0 0.6 1.1 0.3 0.2 1.1 0.4 0.4 0.7 0.7 0.4 1.0 1.0 0.4 0.9 2.0 0.2 0.3 0.2 3.0 3.1 5.1 4.2 4.0 3.6 4.9 3.7 4.0 3.7 4.2 3.5 13.6 9.6 19.3 11.8 7.3 29.6 16.5 4.4 43.9 5.3 34.1 13.6 27.7 7.2 11.4 5.5 2.1 26.9 11.3 10.6 0.0 7.4 4.3 22.6 9.7 3.7 9.0 5.2 15.6 5.3 4.5 52.7 49.5 42.7 10.2 4.1 1.1 29.8 7.0 6.7 22.8 6.4 12.2 2.9 8.8 2.7 6.8 18.3 21.4 7.5 1.0 2.5 2.1 16.1 3.3 9.6 5.4 4.9 14.0 16.5 5.6 2.0 12.7 5.1 0.0 84.5 14.2 6.7 4.1 35.2 50.4 156.4 7.5 3.1 6.7 28.9 SLC25A43 ENSG00000077713 "Solute carrier family 25 member 43" Q8WUT9 X 119399336-119454478 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 30.7;Oligodendrocyte precursor cells: 36.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035188, HPA078530" Uncertain Approved Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA035188: AB_10602400, HPA078530: " "unprognostic (6.05e-3)" "unprognostic (1.48e-1)" "unprognostic (9.92e-2)" "prognostic unfavorable (3.76e-5)" "unprognostic (4.99e-3)" "unprognostic (1.59e-2)" "unprognostic (3.26e-2)" "unprognostic (2.74e-2)" "unprognostic (7.19e-2)" "unprognostic (2.14e-1)" "unprognostic (2.80e-3)" "unprognostic (1.26e-1)" "prognostic unfavorable (5.06e-8)" "unprognostic (2.63e-1)" "unprognostic (2.62e-1)" "unprognostic (1.96e-2)" "unprognostic (4.92e-2)" 10.6 2.6 3.1 7.3 3.4 1.8 9.3 3.3 4.1 8.2 5.4 14.0 14.2 5.0 3.4 21.4 5.3 4.3 5.0 3.2 3.6 7.7 10.6 10.2 5.5 4.3 3.5 6.0 5.9 6.9 1.9 8.3 3.9 4.6 15.5 0.5 10.8 4.6 1.6 16.3 12.8 8.8 3.5 4.9 8.9 2.1 3.6 3.6 4.2 4.5 11.3 7.9 11.3 3.8 32.4 23.3 1.9 9.2 30.0 44.5 12.2 17.9 21.7 13.8 13.2 12.4 16.0 4.0 10.2 47.4 41.1 23.2 18.2 16.0 12.4 28.5 5.4 11.3 7.4 16.4 19.3 10.6 11.7 18.8 28.3 22.5 19.8 18.9 16.6 6.1 2.3 17.1 15.7 58.9 0.1 15.9 10.3 16.6 35.1 3.2 0.0 4.6 22.3 10.9 1.5 0.0 23.0 47.8 29.1 7.3 8.5 11.0 24.2 22.2 7.1 25.0 28.0 0.4 14.2 8.3 22.3 17.8 19.7 0.0 3.5 0.2 0.9 4.9 1.7 4.4 1.8 2.9 6.0 3.7 0.9 1.8 0.1 6.4 11.2 1.6 1.5 1.6 3.1 3.4 3.3 4.1 3.2 3.6 4.3 3.5 3.9 3.5 3.6 3.8 8.3 6.4 9.7 30.7 8.0 7.8 7.3 8.9 9.6 0.2 6.1 6.6 1.6 2.8 5.6 3.7 0.0 11.9 9.1 21.8 9.8 4.5 0.0 0.9 7.6 6.9 7.3 3.4 10.3 8.9 7.1 11.8 9.7 1.8 8.2 2.1 6.4 5.8 10.3 0.0 6.2 9.6 4.1 7.1 13.6 0.4 8.1 7.5 10.6 1.0 11.9 0.2 9.2 36.7 1.4 13.9 11.4 5.7 2.8 5.4 19.8 9.6 2.0 0.4 0.0 7.8 9.2 0.5 2.3 19.8 13.9 6.8 6.8 1.0 12.2 5.8 SLC25A45 ENSG00000162241 "Solute carrier family 25 member 45" Q8N413 11 65375192-65383701 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 34.2" "Cell type enhanced" "Detected in many" "dendritic cells: 46.7;NK-cells: 103.0;Proximal enterocytes: 90.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 17.5;Karpas-707: 22.8;RPMI-8226: 17.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA042495, HPA050821" Uncertain Approved Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 25: Pancreas - Digestion" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA042495: , HPA050821: AB_2681249" "unprognostic (3.73e-2)" "unprognostic (2.19e-3)" "unprognostic (8.44e-4)" "unprognostic (6.17e-3)" "unprognostic (2.57e-2)" "unprognostic (2.84e-7)" "unprognostic (7.57e-3)" "unprognostic (4.59e-2)" "unprognostic (1.44e-1)" "unprognostic (4.06e-2)" "prognostic favorable (2.83e-4)" "unprognostic (1.96e-1)" "unprognostic (1.08e-2)" "unprognostic (1.45e-1)" "unprognostic (1.54e-1)" "unprognostic (6.18e-2)" "unprognostic (1.43e-1)" 3.7 3.3 3.1 5.8 3.3 4.9 4.7 2.8 4.1 1.9 2.6 3.4 5.6 1.8 2.5 2.5 2.0 2.0 3.8 3.1 3.1 6.5 12.1 3.9 10.1 3.7 3.1 1.9 34.2 3.0 6.6 1.9 3.5 3.8 1.8 0.3 6.3 1.9 7.1 2.9 7.6 1.3 3.3 13.3 2.8 1.9 3.1 8.0 12.1 3.7 6.6 2.0 1.9 4.0 0.4 5.8 0.2 8.5 1.5 0.7 4.2 1.0 2.6 0.5 0.5 1.4 2.7 5.2 4.7 2.4 2.1 0.8 0.6 0.4 0.0 17.5 1.2 5.7 3.2 0.4 0.9 1.8 5.7 1.9 0.1 0.7 0.5 0.4 0.9 9.9 0.8 22.8 0.9 1.9 4.2 0.1 0.3 0.3 2.6 7.7 1.1 17.1 0.9 0.1 2.8 3.7 1.8 4.5 1.0 0.5 2.4 0.9 1.7 0.6 2.0 5.5 0.4 9.5 6.4 1.5 1.7 1.3 3.3 10.5 6.3 4.8 8.8 11.2 9.3 10.6 7.8 8.5 6.9 11.9 12.4 9.3 3.9 17.1 13.3 23.0 7.7 3.1 3.1 3.3 2.8 4.1 3.1 3.1 3.7 3.1 3.5 3.3 3.1 4.0 5.0 0.0 5.6 0.3 40.0 2.8 5.9 4.2 3.4 12.3 10.7 7.7 5.6 8.6 4.7 12.9 0.0 2.1 46.7 14.4 0.0 5.9 5.1 6.2 3.1 6.0 6.7 3.0 5.2 5.4 1.7 7.7 5.6 7.9 4.5 21.8 6.8 14.0 7.3 6.7 0.6 16.7 4.1 9.7 14.4 3.9 6.8 11.7 5.4 4.7 18.4 5.5 103.0 1.5 3.9 5.2 12.5 3.8 15.3 7.0 90.9 6.9 12.3 0.4 6.6 12.6 3.6 2.2 0.4 2.2 2.0 1.5 31.6 11.8 13.3 4.6 SLC2A10 GLUT10 ENSG00000197496 "Solute carrier family 2 member 10" O95528 20 46709649-46736347 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 43.6;Intestinal goblet cells: 56.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 75 "basophil: 20.9" "Lineage enriched" "Detected in single" 75 "granulocytes: 20.9" "Cell line enhanced" "Detected in many" "ASC diff: 45.8;HSkMC: 56.6;OE19: 49.8;SK-MEL-30: 60.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041015, HPA055673" Approved Supported Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol "HPA041015: AB_2677252, HPA055673: AB_2682879" "unprognostic (8.94e-3)" "unprognostic (2.62e-3)" "unprognostic (2.06e-1)" "unprognostic (1.85e-1)" "unprognostic (6.17e-3)" "unprognostic (1.04e-1)" "unprognostic (7.68e-2)" "unprognostic (2.80e-1)" "unprognostic (1.83e-1)" "unprognostic (8.06e-2)" "unprognostic (4.94e-3)" "unprognostic (1.70e-1)" "unprognostic (3.63e-3)" "unprognostic (1.25e-2)" "unprognostic (1.05e-1)" "unprognostic (3.00e-1)" "unprognostic (5.96e-2)" 7.0 5.9 4.0 3.5 4.1 1.2 15.3 3.4 3.9 19.4 18.9 12.7 5.4 7.9 8.7 5.1 9.9 10.3 5.2 3.8 3.7 3.5 41.4 6.9 1.7 5.2 4.7 9.9 17.4 19.5 6.3 11.6 4.0 31.3 16.0 1.6 24.0 9.9 1.5 3.6 5.3 8.5 3.8 2.6 22.8 2.6 4.0 1.6 19.5 2.7 2.1 9.3 8.4 3.4 0.0 0.1 11.3 11.7 45.8 38.9 34.2 22.2 30.2 10.1 12.0 0.9 38.9 0.0 16.3 40.6 0.0 0.2 0.0 1.1 4.8 0.0 0.3 3.3 0.0 18.6 32.2 0.0 0.0 56.6 1.0 6.2 0.0 11.8 4.2 0.0 0.2 0.1 17.5 41.3 0.0 1.2 4.3 49.8 2.9 0.0 1.6 0.1 0.0 10.6 0.0 1.8 4.3 7.2 60.3 8.1 5.4 9.2 2.6 21.7 9.1 17.2 2.9 0.3 0.1 0.0 0.1 0.0 4.6 20.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 4.0 4.1 3.4 3.9 3.8 3.7 5.2 4.7 4.0 3.8 4.0 3.4 4.2 6.4 6.3 12.4 0.8 0.6 6.1 7.8 5.2 0.0 29.6 14.4 6.4 7.2 15.8 1.8 0.0 2.7 0.4 11.4 0.0 7.4 0.2 3.2 17.8 4.6 3.6 6.1 0.1 5.6 16.3 16.7 23.4 4.0 6.3 10.7 8.6 43.6 1.1 0.0 0.4 56.6 12.2 1.9 1.3 1.6 26.4 0.4 1.8 2.8 0.0 5.5 0.0 10.1 0.3 5.1 10.3 17.3 2.8 23.9 1.7 0.8 27.5 0.5 13.1 5.1 6.3 0.8 0.3 4.2 1.0 2.1 0.5 3.6 14.6 10.9 SLC32A1 "bA122O1.1, VGAT, VIAAT" ENSG00000101438 "Solute carrier family 32 member 1" Q9H598 20 38724486-38729372 "Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 39.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 14.7;Horizontal cells: 58.9;Inhibitory neurons: 20.7" "Cancer enhanced" "Detected in single" "glioma: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "MOLT-4: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037156, HPA058859, HPA059985" Enhanced Supported Approved Cytosol NA NA "Cluster 65: Brain - Ion transport" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "CAB037156: AB_532294, HPA058859: AB_2683836, HPA059985: AB_2684187" "unprognostic (1.13e-2)" "unprognostic (2.09e-1)" "unprognostic (1.17e-1)" "unprognostic (6.57e-2)" 0.0 0.0 12.4 0.0 39.8 0.2 0.0 3.4 22.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 36.5 0.3 0.0 0.0 0.0 14.2 6.8 0.0 0.0 0.0 7.6 0.0 8.7 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.5 5.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 12.4 39.8 3.4 22.0 2.4 36.5 14.2 6.8 8.7 6.3 5.1 1.2 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 14.7 0.0 0.0 0.4 0.0 0.1 0.0 4.2 0.0 1.3 0.0 0.0 0.0 2.5 0.2 0.0 0.4 1.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.9 20.7 0.0 0.0 0.0 0.4 0.6 0.0 0.5 0.0 0.0 0.0 1.0 0.0 0.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 3.1 0.0 0.0 0.1 2.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLC35E4 ENSG00000100036 "Solute carrier family 35 member E4" Q6ICL7 22 30635781-30669016 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 22.9" "Group enriched" "Detected in many" 4 "Early spermatids: 122.2;Late spermatids: 108.6;Spermatocytes: 55.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HDLM-2: 22.8;U-2197: 21.0;U-87 MG: 22.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049558 Approved Approved Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA049558: AB_2680817" "unprognostic (2.09e-1)" "unprognostic (1.88e-1)" "unprognostic (2.05e-1)" "unprognostic (1.01e-2)" "unprognostic (4.99e-2)" "unprognostic (2.04e-1)" "unprognostic (3.03e-4)" "unprognostic (5.71e-2)" "unprognostic (7.85e-2)" "unprognostic (1.76e-1)" "unprognostic (1.05e-2)" "unprognostic (2.39e-2)" "unprognostic (3.45e-7)" "unprognostic (2.77e-3)" "unprognostic (1.77e-1)" "unprognostic (2.24e-2)" "unprognostic (8.05e-3)" 2.6 1.8 3.5 1.4 5.0 1.5 2.2 2.9 6.7 2.6 0.4 3.2 1.0 3.5 1.3 2.8 2.5 1.1 3.4 4.1 3.5 2.4 0.5 2.0 0.8 4.7 4.5 1.9 1.7 1.7 2.3 0.4 4.7 2.3 1.7 1.5 2.1 1.3 11.1 5.3 1.8 1.4 1.9 1.9 3.4 22.9 4.5 0.3 1.6 2.8 0.5 3.1 2.8 7.3 10.0 4.3 1.6 3.2 4.3 10.9 0.9 6.4 5.6 4.3 4.0 0.3 2.6 0.7 3.4 6.6 6.1 6.2 2.8 3.7 2.2 22.8 3.1 0.1 3.3 0.3 6.1 0.4 2.7 3.5 1.6 17.3 5.4 6.8 14.9 0.8 0.9 2.8 6.8 2.8 0.4 1.9 1.9 2.9 16.2 1.8 3.2 0.3 2.0 0.8 8.7 3.4 6.6 2.8 3.2 0.7 2.0 0.7 20.0 18.2 5.8 21.0 6.2 0.8 0.9 0.3 22.3 0.3 4.9 0.6 0.6 0.1 0.2 0.8 0.4 0.0 0.6 0.9 1.1 0.1 0.5 0.5 0.2 0.6 0.7 0.3 0.7 0.3 3.5 5.0 2.9 6.7 4.1 3.5 4.7 4.5 4.7 1.9 4.5 7.3 5.7 0.0 1.5 2.6 2.7 14.5 2.5 1.9 8.0 10.6 2.0 3.7 1.9 0.0 1.2 1.8 22.9 0.1 4.8 5.4 0.0 3.4 122.2 6.0 4.9 9.1 2.4 0.8 4.2 2.3 0.5 3.7 2.6 2.0 1.3 4.1 4.2 0.3 1.8 11.8 4.9 4.4 2.0 1.2 7.7 108.6 3.4 8.0 3.6 4.7 2.5 17.2 1.0 2.5 9.2 2.5 11.1 3.8 3.1 1.7 1.2 0.4 5.7 10.5 0.0 3.9 5.0 55.1 3.8 4.2 19.0 0.1 4.9 2.4 5.0 2.1 SLC44A5 "CTL5, MGC34032" ENSG00000137968 "Solute carrier family 44 member 5" Q8NCS7 1 75202131-75611116 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 10.7" "Group enriched" "Detected in many" 4 "Excitatory neurons: 274.5;Inhibitory neurons: 563.3;Oligodendrocyte precursor cells: 265.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 7.7;RPTEC TERT1: 7.4;SH-SY5Y: 11.5;SuSa: 11.7;TIME: 14.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047455, HPA051011" Uncertain Approved Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA047455: AB_2680054, HPA051011: AB_2681309" "unprognostic (9.00e-2)" "unprognostic (1.91e-1)" "unprognostic (8.38e-2)" "unprognostic (1.04e-3)" "unprognostic (4.57e-1)" "unprognostic (1.69e-1)" "unprognostic (1.77e-2)" "unprognostic (1.12e-1)" "unprognostic (1.04e-1)" "unprognostic (5.78e-3)" "unprognostic (6.41e-2)" "unprognostic (9.19e-2)" "prognostic unfavorable (6.52e-4)" "unprognostic (1.70e-3)" "unprognostic (1.47e-1)" "unprognostic (2.68e-2)" "unprognostic (4.30e-1)" 0.3 0.7 1.5 0.5 1.9 0.3 5.5 0.0 3.4 1.1 0.0 2.1 1.2 0.7 0.4 6.6 3.6 1.0 2.5 2.3 1.7 2.0 1.0 0.6 0.5 2.6 1.6 1.1 1.7 3.7 3.1 3.8 2.8 0.8 2.7 2.5 1.4 0.2 1.6 10.7 1.4 0.2 2.0 0.8 1.5 4.5 2.3 2.5 0.7 1.5 2.1 1.6 2.0 1.2 0.2 0.2 4.6 5.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.7 0.0 0.0 2.7 0.0 0.0 0.0 0.9 0.0 0.0 0.0 4.7 0.6 1.2 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.9 0.4 2.7 2.7 0.0 0.0 1.9 0.0 4.7 3.2 0.6 0.0 0.0 2.3 7.4 5.2 1.1 11.5 0.0 4.8 0.0 11.7 0.2 0.0 14.7 0.4 1.3 0.0 1.5 2.1 2.1 3.2 0.2 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.2 0.7 0.1 0.2 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.5 1.9 0.0 3.4 2.3 1.7 2.6 1.6 2.8 2.0 2.3 1.2 0.1 0.0 1.1 12.4 0.4 1.9 1.0 0.4 0.0 4.0 2.9 1.7 0.8 0.0 1.0 0.0 0.0 9.1 0.0 2.0 0.0 0.1 86.9 1.0 0.1 0.6 2.4 0.0 274.5 0.9 3.9 0.4 0.0 0.3 0.0 20.1 7.5 0.0 1.1 0.0 563.3 1.0 0.0 0.0 0.2 35.2 0.9 0.1 0.0 6.5 0.0 0.0 0.0 265.4 10.1 0.2 0.2 0.0 0.1 1.1 0.0 0.1 2.5 0.8 0.0 0.6 0.2 0.4 0.4 0.9 6.7 3.8 0.1 0.5 1.2 3.6 SLC66A3 "C2orf22, MGC33602, PQLC3" ENSG00000162976 "Solute carrier family 66 member 3" Q8N755 2 11155198-11178870 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 15.5;Cytotrophoblasts: 17.5;Extravillous trophoblasts: 82.4;Fibroblasts: 16.1;Hofbauer cells: 56.3" "Cancer enhanced" "Detected in all" "testis cancer: 72.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 64.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061607 Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA061607: AB_2797264" "unprognostic (3.22e-2)" "unprognostic (1.17e-1)" "unprognostic (2.19e-1)" "unprognostic (5.55e-2)" "unprognostic (1.65e-2)" "unprognostic (2.16e-1)" "unprognostic (1.09e-3)" "unprognostic (9.11e-2)" "unprognostic (3.14e-1)" "unprognostic (2.24e-1)" "unprognostic (4.93e-3)" "unprognostic (2.93e-1)" "unprognostic (1.19e-2)" "unprognostic (1.12e-1)" "unprognostic (2.21e-1)" "unprognostic (2.34e-1)" "unprognostic (4.00e-2)" 30.6 26.3 9.7 17.3 9.8 9.9 29.2 10.2 14.0 38.4 17.0 17.6 10.8 23.8 47.3 14.3 19.8 27.8 15.1 9.6 10.2 25.8 17.5 27.0 22.5 12.0 10.1 29.9 29.0 13.2 5.8 14.4 12.0 22.6 19.3 2.5 17.1 19.8 8.5 14.7 15.5 21.4 11.3 39.8 20.0 11.6 10.2 14.3 17.3 17.1 16.8 22.5 17.2 14.2 7.1 23.3 4.3 13.4 64.6 43.9 15.5 14.8 19.3 6.8 8.0 4.3 27.3 2.5 10.5 28.5 29.3 9.1 6.9 7.3 6.8 43.8 3.2 6.5 2.7 3.0 26.1 3.3 19.5 31.7 24.5 4.3 9.7 14.5 15.5 15.3 6.2 14.8 18.8 31.6 4.8 6.6 9.1 25.2 7.6 6.2 7.2 7.7 25.8 11.6 1.6 7.2 12.4 37.9 27.9 19.1 33.9 12.2 22.0 9.6 3.8 10.2 4.1 25.2 19.6 1.2 24.9 15.5 19.4 79.4 153.7 150.3 68.8 194.9 60.7 42.4 65.6 66.7 153.6 31.9 35.9 49.5 9.5 59.9 207.4 28.7 73.2 166.2 9.7 9.8 10.2 14.0 9.6 10.2 12.0 10.1 12.0 11.3 10.2 14.2 15.5 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 17.5 11.9 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 82.4 16.1 0.0 0.0 0.0 0.0 0.0 0.0 56.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 11.2 2.2 0.0 0.0 0.0 SLFNL1 FLJ23878 ENSG00000171790 "Schlafen like 1" Q499Z3 1 41015597-41023237 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "testis: 76.0" "Group enriched" "Detected in some" 76 "Early spermatids: 217.4;Late spermatids: 668.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 5.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054956 Approved Cytosol NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA054956: AB_2682649" "unprognostic (7.01e-3)" "unprognostic (1.62e-1)" "unprognostic (1.54e-3)" "unprognostic (4.35e-2)" "unprognostic (3.39e-1)" "unprognostic (4.11e-4)" "unprognostic (8.98e-3)" "unprognostic (1.02e-3)" "unprognostic (8.40e-3)" "unprognostic (1.50e-1)" "unprognostic (2.51e-1)" "unprognostic (3.71e-4)" "unprognostic (2.70e-3)" "unprognostic (1.10e-1)" "unprognostic (2.09e-1)" "unprognostic (3.26e-1)" "unprognostic (2.43e-1)" 0.3 0.3 1.1 0.2 1.1 0.5 0.2 1.4 1.6 1.2 2.8 1.0 0.3 1.0 0.0 0.3 1.1 0.2 0.4 1.0 1.1 0.7 1.6 2.0 0.3 1.0 0.8 1.3 0.7 0.0 0.9 0.1 0.9 1.4 0.0 0.6 4.2 0.1 0.3 0.3 1.1 0.0 0.7 0.4 0.4 76.0 0.9 0.0 0.7 0.0 0.0 0.7 0.6 0.9 0.5 0.8 0.4 0.6 0.0 0.1 2.5 1.1 0.0 0.0 0.0 5.4 0.5 0.9 0.9 0.0 0.2 0.9 0.0 0.0 0.0 0.7 1.5 0.7 1.5 0.7 0.3 1.0 0.6 0.1 0.1 0.0 0.0 0.2 0.1 0.8 0.6 1.1 0.0 0.4 0.6 1.1 0.9 0.1 1.3 1.3 0.6 0.6 0.0 1.4 0.6 0.3 0.2 0.5 0.4 0.4 0.3 0.6 0.4 1.0 1.2 0.5 0.8 0.6 0.3 1.1 0.1 1.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.1 1.4 1.6 1.0 1.1 1.0 0.8 0.9 0.7 0.9 0.9 0.1 0.0 5.1 0.3 0.0 0.3 0.1 0.0 0.0 0.7 0.3 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 217.4 0.1 0.2 0.2 0.0 0.0 2.2 0.2 0.0 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.3 668.9 3.4 0.2 0.0 0.0 0.0 0.0 0.0 0.5 2.4 0.0 0.0 2.2 0.0 0.2 0.1 0.2 0.0 0.1 0.0 0.1 0.0 5.8 2.3 0.0 0.1 0.0 0.1 0.1 0.1 0.0 SLX4IP "C20orf94, dJ1099D15.3" ENSG00000149346 "SLX4 interacting protein" Q5VYV7 20 10435305-10636829 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 57.1;Microglial cells: 53.4;Oligodendrocyte precursor cells: 55.3;Oligodendrocytes: 111.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046372 Approved Approved Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA046372: AB_2679641" "unprognostic (4.96e-2)" "unprognostic (2.91e-1)" "unprognostic (2.34e-1)" "unprognostic (2.66e-1)" "unprognostic (1.05e-1)" "unprognostic (3.59e-2)" "unprognostic (1.20e-3)" "unprognostic (1.58e-2)" "unprognostic (2.58e-1)" "unprognostic (1.14e-1)" "unprognostic (4.56e-3)" "unprognostic (3.91e-1)" "prognostic unfavorable (9.51e-4)" "unprognostic (6.52e-2)" "unprognostic (3.42e-1)" "unprognostic (1.30e-2)" "unprognostic (1.55e-2)" 1.5 2.0 3.0 1.7 3.7 1.7 2.1 3.3 3.3 1.8 3.1 2.1 1.8 1.2 4.8 2.7 2.2 1.9 1.4 2.8 3.8 2.7 3.2 1.4 2.2 3.7 3.6 1.6 2.9 3.3 4.7 1.6 3.7 2.3 2.3 5.3 1.9 1.3 4.1 3.7 2.1 1.0 3.4 2.5 2.3 2.4 3.9 2.6 2.7 0.8 2.4 1.7 2.3 4.3 3.3 6.1 3.0 8.2 1.7 2.3 2.5 1.6 1.8 2.5 2.7 4.6 4.1 5.2 2.6 1.9 3.5 6.4 4.6 4.8 4.0 0.0 1.7 4.7 2.1 6.2 2.9 5.1 2.7 3.2 4.1 3.2 6.2 3.3 2.5 4.5 3.9 4.3 3.1 2.8 7.7 7.5 5.5 4.0 2.0 5.5 8.0 4.7 3.7 3.2 5.4 4.1 4.7 7.3 4.9 4.2 8.0 2.6 3.7 2.0 4.2 2.5 1.9 4.5 11.1 6.3 1.5 4.8 3.6 0.3 1.0 0.4 0.7 1.3 1.2 1.1 1.1 0.9 1.2 1.2 1.0 0.9 0.8 1.3 1.7 2.0 1.5 0.5 3.0 3.7 3.3 3.3 2.8 3.8 3.7 3.6 3.7 3.4 3.9 4.3 3.2 6.4 6.4 57.1 6.9 0.6 5.6 5.1 3.4 11.8 6.9 5.0 3.6 8.6 7.6 1.8 16.7 11.3 2.9 7.2 11.7 9.8 2.1 10.5 7.3 5.9 10.2 7.4 33.6 3.9 8.3 4.8 8.2 7.4 8.2 12.3 18.9 6.4 8.1 10.1 40.7 8.1 4.1 6.5 2.3 4.2 5.0 4.7 5.4 53.4 11.0 10.0 11.3 55.3 111.8 3.9 8.4 4.5 5.9 3.7 6.8 10.8 3.3 19.6 0.0 6.3 6.6 8.0 10.6 8.4 1.6 6.6 5.1 8.6 8.1 4.8 SNAP47 "C1orf142, SNAP-47, SVAP1" ENSG00000143740 "Synaptosome associated protein 47" Q5SQN1 1 227728200-227781826 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 95.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028167 Supported Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 89: Fibroblasts - ECM organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA028167: AB_10603032" "unprognostic (3.31e-2)" "unprognostic (1.31e-1)" "unprognostic (1.93e-2)" "unprognostic (7.31e-2)" "unprognostic (4.88e-2)" "unprognostic (2.23e-2)" "unprognostic (1.20e-1)" "unprognostic (7.28e-2)" "unprognostic (1.48e-1)" "unprognostic (2.07e-1)" "unprognostic (1.34e-2)" "unprognostic (7.26e-2)" "unprognostic (1.48e-1)" "unprognostic (6.14e-2)" "unprognostic (4.81e-1)" "unprognostic (1.11e-1)" "unprognostic (2.05e-1)" 14.2 43.8 19.8 10.0 22.0 10.1 16.9 18.3 23.8 23.9 12.5 20.5 10.1 28.9 15.3 14.0 25.9 12.4 38.6 22.4 17.0 19.4 27.0 11.7 18.1 14.4 15.4 47.2 16.5 23.5 27.4 20.1 15.2 17.3 8.9 12.9 18.2 12.1 36.3 16.6 15.3 18.5 15.3 14.6 17.0 38.6 16.7 17.1 17.1 23.4 14.1 19.9 14.7 17.7 33.5 44.2 27.2 27.7 30.3 25.1 35.0 21.2 33.7 35.5 26.5 29.4 29.8 23.8 37.9 33.2 27.3 36.2 33.6 37.9 27.6 48.1 63.4 19.8 28.0 18.9 21.6 30.8 17.8 28.0 32.2 43.3 24.7 28.3 29.4 28.7 37.6 23.7 32.1 22.0 31.5 29.0 44.3 42.5 65.1 32.8 32.3 37.7 20.4 28.1 50.5 32.1 33.6 44.0 33.5 26.4 55.1 27.8 21.3 30.9 38.4 30.7 52.5 30.2 23.2 28.9 28.0 23.0 40.8 19.1 21.0 34.0 29.4 21.2 28.3 22.6 33.1 34.2 23.3 21.3 27.1 25.4 7.4 30.5 27.7 24.0 46.4 25.4 19.8 22.0 18.3 23.8 22.4 17.0 14.4 15.4 15.2 15.3 16.7 17.7 10.1 6.4 13.1 9.4 16.1 13.4 15.9 16.2 16.5 30.8 16.5 14.7 13.0 22.8 13.2 14.7 27.1 24.3 18.7 8.7 35.2 19.9 49.4 7.2 14.3 11.7 16.2 13.5 12.0 18.2 28.4 15.1 10.7 6.9 5.7 21.0 11.0 13.8 16.3 42.1 9.6 8.6 22.4 8.8 6.2 95.9 25.7 7.6 12.4 8.4 22.3 30.5 45.3 6.6 6.1 17.0 3.3 20.7 22.7 16.5 12.4 15.8 8.9 33.5 13.1 12.0 14.0 41.9 26.4 8.5 15.3 27.5 19.4 23.3 10.5 10.1 SND1 "p100, TDRD11" ENSG00000197157 "Staphylococcal nuclease and tudor domain containing 1" Q7KZF4 7 127652194-128092609 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Endonuclease, Hydrolase, Nuclease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 255.0;Syncytiotrophoblasts: 267.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002529, HPA002632, CAB019323" Enhanced Enhanced Cytosol NA NA 1800000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "CAB019323: , HPA002529: AB_1857317, HPA002632: AB_1857316" "unprognostic (2.06e-1)" "unprognostic (8.27e-3)" "unprognostic (2.21e-1)" "prognostic favorable (1.95e-4)" "unprognostic (5.10e-3)" "unprognostic (6.83e-2)" "unprognostic (1.17e-2)" "unprognostic (2.91e-2)" "unprognostic (4.22e-2)" "unprognostic (3.81e-2)" "unprognostic (1.56e-1)" "unprognostic (2.30e-1)" "unprognostic (1.36e-2)" "unprognostic (9.96e-2)" "unprognostic (1.99e-1)" "unprognostic (3.42e-2)" "unprognostic (2.26e-3)" 48.5 52.5 19.1 57.8 22.6 65.8 56.7 25.3 21.4 76.9 41.0 51.3 54.2 67.2 90.6 47.7 65.1 37.3 45.3 19.9 33.3 33.9 67.5 46.7 53.0 29.7 29.4 87.3 179.0 50.8 52.7 86.7 29.9 59.0 49.4 32.1 102.2 57.7 41.9 43.7 45.3 66.5 26.2 45.8 65.7 38.5 25.4 67.5 66.0 40.0 65.3 50.0 41.8 33.5 160.0 141.8 106.3 193.5 156.6 162.7 145.3 183.5 214.8 163.8 182.5 184.6 134.6 210.6 90.4 225.7 137.8 130.4 150.7 198.1 158.6 116.1 127.2 116.1 153.0 177.9 284.2 181.9 109.6 241.3 216.3 140.0 232.3 185.7 206.2 85.1 131.3 204.9 165.0 118.6 199.5 135.6 119.5 159.7 173.6 136.8 94.6 476.1 128.1 110.5 133.0 143.7 132.8 606.6 217.5 157.8 76.2 127.2 207.3 132.3 86.4 243.3 144.7 250.1 101.1 217.0 265.6 153.6 245.2 49.7 86.4 17.1 67.0 76.6 78.0 70.1 50.0 54.0 87.4 44.6 34.9 39.8 6.2 59.7 66.1 92.9 43.4 92.9 19.1 22.6 25.3 21.4 19.9 33.3 29.7 29.4 29.9 26.2 25.4 33.5 20.3 16.0 44.7 60.4 56.7 19.6 24.7 32.9 22.2 17.1 41.0 28.6 29.2 35.8 28.9 29.5 20.9 255.0 44.3 28.8 17.6 62.8 20.1 21.9 51.9 30.3 73.1 47.5 128.0 96.7 106.1 40.7 54.6 39.5 34.9 54.4 25.0 49.8 81.9 30.3 116.0 59.4 18.3 52.8 36.7 68.1 45.7 50.8 33.8 78.7 72.5 16.7 32.0 84.9 89.9 58.6 29.8 41.3 124.6 42.8 38.2 33.1 19.0 32.7 32.9 27.0 34.4 23.4 28.0 37.6 27.4 267.6 37.2 74.0 58.3 27.0 SNN ENSG00000184602 Stannin O75324 16 11668455-11679152 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 126.0;skeletal muscle: 114.9" "Cell type enhanced" "Detected in many" "Langerhans cells: 108.2;Macrophages: 64.7;Muller glia cells: 146.9" "Cancer enhanced" "Detected in all" "glioma: 62.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "AF22: 74.9;REH: 73.1" "Low region specificity" "Detected in all" HPA011055 Approved Uncertain Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA011055: AB_1857326" "unprognostic (1.94e-1)" "unprognostic (7.26e-2)" "unprognostic (2.40e-1)" "unprognostic (1.84e-1)" "unprognostic (2.44e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (1.85e-6)" "unprognostic (4.51e-2)" "unprognostic (3.45e-1)" "unprognostic (2.82e-1)" "unprognostic (1.07e-2)" "unprognostic (2.14e-1)" "prognostic favorable (1.83e-5)" "unprognostic (4.91e-2)" "unprognostic (2.09e-1)" "unprognostic (3.58e-1)" "unprognostic (4.72e-2)" 57.4 29.4 114.1 19.8 126.0 24.5 24.3 91.6 101.7 18.3 49.4 16.9 9.1 14.0 20.2 19.1 12.8 22.0 28.4 117.4 87.9 14.5 9.3 21.6 30.8 92.8 102.9 17.0 8.7 9.9 15.4 8.2 83.6 14.3 5.7 40.5 18.3 21.9 114.9 14.8 14.4 10.5 93.3 34.6 14.1 3.9 108.9 28.6 17.3 36.9 27.5 18.5 14.6 89.0 7.6 7.2 74.9 20.5 48.7 13.8 7.2 3.2 6.8 9.0 9.1 11.7 5.2 7.8 30.6 10.6 15.9 14.6 22.7 9.1 6.9 2.1 5.1 25.8 8.1 15.3 12.9 1.8 14.9 12.1 40.7 4.8 10.0 12.7 16.8 22.4 4.1 12.0 8.4 12.7 21.0 5.8 39.0 9.5 5.2 73.1 10.0 53.8 8.5 21.9 44.4 18.0 17.4 22.6 11.5 29.1 9.1 15.2 15.1 10.4 21.3 61.2 3.3 4.8 3.3 18.1 6.2 22.0 13.4 0.1 21.0 16.0 0.6 36.2 0.6 15.2 3.3 1.5 19.9 15.5 6.1 4.5 53.0 0.7 48.6 8.0 2.2 17.1 114.1 126.0 91.6 101.7 117.4 87.9 92.8 102.9 83.6 93.3 108.9 89.0 27.5 0.0 6.1 11.8 46.8 18.4 19.9 9.5 18.8 7.5 7.3 10.0 16.6 14.3 6.9 5.5 0.0 1.3 16.8 0.4 25.4 16.7 0.7 6.8 7.8 17.9 5.3 0.0 28.6 18.3 23.1 9.4 3.1 8.4 13.4 5.7 27.1 3.0 20.7 6.7 11.6 0.5 14.2 39.5 108.2 0.5 5.0 64.7 21.4 11.2 58.2 146.9 4.1 8.5 5.0 14.6 0.3 15.4 2.9 14.6 0.9 5.2 6.7 6.5 6.6 17.7 16.9 0.4 3.8 15.3 19.0 1.4 12.1 1.1 0.4 13.2 SNRPD2 "Sm-D2, SNRPD1" ENSG00000125743 "Small nuclear ribonucleoprotein D2 polypeptide" P62316 19 45687460-45692569 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041437 Supported Supported Cytosol NA NA 76000 "Cluster 30: Non-specific - Translation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" Cytosol "HPA041437: AB_10795119" "unprognostic (1.48e-1)" "unprognostic (1.11e-1)" "unprognostic (2.18e-1)" "unprognostic (1.94e-2)" "unprognostic (6.63e-2)" "unprognostic (6.84e-2)" "unprognostic (1.23e-3)" "unprognostic (2.08e-1)" "unprognostic (7.71e-2)" "unprognostic (3.50e-1)" "unprognostic (4.79e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (8.58e-5)" "unprognostic (1.95e-1)" "unprognostic (6.57e-3)" "unprognostic (1.53e-1)" "unprognostic (7.12e-2)" 201.0 215.1 305.0 237.7 317.2 478.3 390.9 309.5 374.8 267.3 297.8 253.3 170.1 228.8 331.5 244.5 318.1 195.9 265.5 312.2 321.0 215.6 200.1 157.1 442.7 312.2 308.3 440.0 184.9 263.5 202.9 215.3 310.8 201.9 253.5 120.8 197.4 209.7 306.0 245.1 168.1 235.2 311.1 202.2 189.1 167.5 315.5 501.0 214.7 305.6 406.4 312.2 216.4 312.6 970.0 1429.6 863.8 905.4 843.8 797.5 475.5 630.8 777.8 933.3 974.0 814.6 582.4 1119.3 493.9 788.2 624.9 543.7 1180.4 1184.6 888.6 721.6 1428.6 1066.5 756.6 1040.6 585.1 1287.9 646.4 894.2 862.7 798.3 759.9 639.5 960.3 1111.6 996.6 713.1 765.9 1329.7 1274.7 1129.0 780.8 1758.5 776.2 848.1 890.0 896.5 782.0 1249.4 792.7 880.4 828.1 842.8 808.7 705.9 500.2 1378.5 614.2 422.3 694.7 397.5 1198.8 717.5 1949.8 1775.2 601.5 1087.8 691.3 306.6 525.1 275.0 810.3 500.5 1045.6 1309.4 1076.4 964.5 789.1 1155.8 1244.5 1083.7 62.7 885.6 393.8 876.0 1144.9 1776.3 305.0 317.2 309.5 374.8 312.2 321.0 312.2 308.3 310.8 311.1 315.5 312.6 150.6 147.4 211.1 8.1 407.6 470.5 564.5 724.2 463.9 43.1 361.2 650.5 443.3 233.1 372.3 329.2 22.9 607.0 294.3 318.8 665.2 368.8 563.3 190.9 310.2 225.3 310.2 315.9 7.9 350.7 787.7 305.2 199.8 198.2 266.0 284.4 232.3 265.4 475.4 37.0 8.3 492.0 376.4 269.9 470.6 1325.8 347.9 232.5 434.0 9.4 373.9 162.6 373.9 3.5 12.2 318.2 348.5 231.7 341.2 553.5 356.9 768.7 309.3 65.2 164.3 279.4 382.1 286.3 274.7 562.6 422.7 482.8 426.5 216.2 556.9 534.0 SNX18 "SH3PX2, SH3PXD3B, SNAG1" ENSG00000178996 "Sorting nexin 18" Q96RF0 5 54517759-54546586 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Endocytosis, Mitosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 68.0" "Cell type enhanced" "Detected in many" "Granulosa cells: 90.0;Kupffer cells: 87.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037800 Approved Approved Cytosol NA NA 12000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "HPA037800: AB_10672465" "unprognostic (2.22e-2)" "unprognostic (3.96e-3)" "unprognostic (1.92e-1)" "unprognostic (8.98e-2)" "unprognostic (4.12e-1)" "unprognostic (2.22e-1)" "unprognostic (9.26e-2)" "unprognostic (8.94e-2)" "unprognostic (3.98e-2)" "unprognostic (1.41e-1)" "unprognostic (9.13e-2)" "unprognostic (3.81e-3)" "prognostic favorable (1.58e-4)" "unprognostic (6.79e-3)" "unprognostic (7.96e-2)" "unprognostic (2.12e-1)" "unprognostic (1.42e-1)" 14.9 8.7 12.1 11.2 21.3 68.0 9.1 20.4 13.1 11.5 9.1 9.2 9.3 13.5 6.4 10.1 9.4 11.4 7.4 10.3 12.2 12.8 15.1 11.3 13.3 22.8 19.9 26.6 9.3 12.0 3.6 21.8 19.6 8.6 5.5 14.8 11.2 11.5 7.2 7.6 9.5 14.1 18.8 18.8 12.0 7.3 18.6 5.6 15.6 8.0 7.0 11.2 7.7 25.2 9.0 7.4 11.4 13.0 26.2 27.8 61.7 14.8 37.1 7.6 12.6 9.1 16.4 0.4 23.1 23.1 13.9 8.2 10.8 14.5 9.6 4.6 7.7 2.7 4.6 5.7 43.5 5.0 2.5 44.1 17.2 10.4 10.8 13.5 16.1 6.5 4.8 60.7 13.3 8.6 4.7 5.7 5.7 3.7 7.6 12.4 6.4 14.5 7.4 26.0 14.1 8.3 12.4 14.2 16.2 17.4 16.7 8.4 5.5 28.4 13.8 21.1 15.6 40.0 41.8 2.5 11.0 11.8 29.9 0.0 0.9 0.1 0.7 1.5 0.1 0.8 0.3 0.4 1.1 0.6 0.1 0.5 3.8 1.0 3.8 2.5 0.2 0.3 12.1 21.3 20.4 13.1 10.3 12.2 22.8 19.9 19.6 18.8 18.6 25.2 14.4 54.5 26.8 7.5 16.6 9.8 4.4 12.8 10.2 10.0 13.6 10.5 16.5 7.2 22.5 22.0 73.0 26.5 48.2 4.2 15.6 14.2 0.3 7.5 9.8 16.5 6.1 3.4 10.3 15.2 30.3 23.0 27.5 6.2 5.7 90.0 43.9 28.1 41.6 5.0 9.2 7.3 12.2 87.4 26.2 2.5 14.0 52.1 10.6 37.5 42.6 11.2 35.0 6.6 21.6 12.8 7.3 17.7 12.7 5.6 8.6 6.9 24.0 47.5 0.0 13.3 38.5 3.6 13.1 8.9 11.8 8.2 12.5 58.6 10.8 13.1 SOCS7 "NAP4, NCKAP4" ENSG00000274211 "Suppressor of cytokine signaling 7" O14512 17 38351844-38405593 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 74.1" "Group enriched" "Detected in many" 6 "Early spermatids: 254.0;Late spermatids: 500.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004475 Approved Approved Cytosol NA NA "Cluster 21: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Cytosol "HPA004475: AB_2667194" "prognostic unfavorable (7.49e-4)" "unprognostic (7.93e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (7.87e-4)" "unprognostic (7.93e-2)" "unprognostic (1.33e-1)" "unprognostic (1.43e-3)" "unprognostic (1.23e-1)" "unprognostic (1.77e-1)" "unprognostic (4.12e-3)" "unprognostic (1.97e-3)" "unprognostic (6.62e-2)" "unprognostic (4.91e-3)" "unprognostic (1.55e-2)" "unprognostic (1.53e-1)" "unprognostic (6.65e-2)" "unprognostic (1.88e-1)" 4.2 7.1 8.7 4.3 9.5 4.1 4.8 24.8 9.3 5.7 0.3 6.0 3.9 7.3 6.2 6.1 5.4 2.8 5.2 10.9 5.0 3.9 3.7 4.8 3.5 4.0 6.0 7.2 14.4 11.5 6.6 3.7 3.8 5.2 4.3 12.7 6.2 4.2 14.2 7.9 4.8 5.4 4.3 3.4 7.0 74.1 6.8 6.7 7.7 5.0 4.7 4.9 4.6 6.8 12.3 13.6 14.9 11.1 8.2 6.9 12.2 5.2 4.5 6.2 5.1 10.7 3.6 8.8 7.7 8.4 8.9 7.7 12.8 3.6 7.9 15.6 11.0 8.9 16.4 11.2 2.6 19.7 14.6 4.3 14.2 6.6 8.7 7.8 5.4 4.4 7.2 5.6 7.8 6.7 16.5 12.8 4.8 13.3 2.4 16.7 24.9 7.6 4.1 14.8 26.1 14.1 13.0 8.3 8.7 12.5 15.5 10.3 5.3 6.2 5.2 11.3 16.3 19.0 14.5 12.1 8.4 9.8 12.9 0.0 0.1 0.0 0.3 0.1 0.3 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 8.7 9.5 24.8 9.3 10.9 5.0 4.0 6.0 3.8 4.3 6.8 6.8 4.0 16.0 10.1 21.2 3.5 0.8 7.0 0.0 8.6 47.5 11.1 9.8 26.8 5.7 8.1 1.8 29.2 9.5 6.1 5.3 1.9 6.0 254.0 5.9 7.9 5.1 4.9 4.2 39.0 6.5 4.8 6.4 4.1 6.5 0.0 9.8 7.9 7.8 3.2 35.3 30.6 7.0 0.0 6.8 0.7 500.2 10.5 5.0 1.8 13.1 7.4 11.7 6.2 23.1 20.6 6.6 6.2 9.1 2.1 8.3 4.4 2.9 5.3 15.8 0.0 9.1 6.8 62.1 23.9 8.1 0.9 8.1 5.0 6.0 6.8 7.6 SORD ENSG00000140263 "Sorbitol dehydrogenase" Q00796 15 45023147-45077185 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 163.8;liver: 247.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 138.7;Hepatocytes: 649.4;Prostatic glandular cells: 218.8;Proximal tubular cells: 270.2" "Group enriched" "Detected in all" 4 "liver cancer: 30.3;prostate cancer: 72.5;thyroid cancer: 30.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 10 "basophil: 86.3;eosinophil: 55.9" "Lineage enriched" "Detected in all" 12 "granulocytes: 86.3" "Cell line enhanced" "Detected in many" "SK-BR-3: 57.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040260, HPA040621" Enhanced Approved Cytosol NA NA 2800000 "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA040260: AB_10794872, HPA040621: AB_10795384" "unprognostic (8.18e-2)" "unprognostic (7.58e-2)" "unprognostic (8.19e-2)" "unprognostic (1.51e-1)" "unprognostic (5.69e-3)" "unprognostic (3.90e-2)" "prognostic favorable (6.14e-5)" "unprognostic (3.33e-3)" "unprognostic (1.67e-1)" "unprognostic (4.95e-2)" "unprognostic (7.04e-3)" "unprognostic (1.40e-1)" "unprognostic (4.26e-2)" "unprognostic (1.23e-2)" "unprognostic (8.53e-2)" "unprognostic (2.31e-2)" "unprognostic (1.56e-1)" 2.0 15.7 4.9 3.1 3.8 2.8 53.8 7.4 8.4 163.8 1.9 5.3 7.5 4.3 6.9 10.2 6.7 8.2 5.6 5.0 4.5 50.3 247.0 3.2 2.6 4.3 3.7 2.4 5.7 4.4 3.1 2.5 4.0 87.9 7.8 4.8 5.3 27.0 2.2 16.6 7.2 3.5 4.2 2.3 9.2 12.2 3.9 3.7 89.4 2.8 3.4 9.1 6.9 6.3 12.3 12.2 4.7 20.8 4.4 5.3 5.9 1.8 3.5 12.2 7.0 12.2 5.8 2.7 8.0 5.4 4.1 17.6 19.9 19.1 9.2 29.9 12.3 13.5 12.1 50.3 0.2 18.0 25.5 6.7 18.0 6.6 9.5 5.4 12.5 15.1 11.7 10.6 14.9 8.1 18.4 38.3 39.0 29.4 13.8 0.9 16.6 6.4 16.8 12.1 25.1 12.2 2.1 57.3 5.9 5.2 16.4 22.5 4.7 3.5 38.0 1.6 5.8 8.7 4.5 4.4 14.2 18.6 10.6 86.3 1.7 55.9 1.6 1.5 1.7 5.4 1.3 1.6 1.7 6.9 1.6 1.4 3.8 1.1 2.1 2.4 2.5 2.0 4.9 3.8 7.4 8.4 5.0 4.5 4.3 3.7 4.0 4.2 3.9 6.3 3.9 0.0 3.1 5.5 11.9 7.8 26.5 14.8 17.6 10.8 24.7 17.5 3.2 25.8 28.1 33.1 0.0 1.3 2.3 15.0 29.4 68.2 31.7 40.2 17.4 4.9 84.8 37.5 4.8 138.7 5.1 7.5 31.1 43.7 8.8 11.5 15.7 649.4 16.0 3.3 5.4 32.5 22.4 24.2 6.4 24.1 3.7 12.2 16.0 1.0 13.3 9.0 2.1 7.1 8.9 89.0 18.1 6.0 7.9 218.8 8.0 270.2 42.5 4.7 0.0 8.9 8.9 7.4 2.8 35.1 20.3 1.0 6.5 15.3 39.4 131.2 SOS1 "GF1, GINGF, HGF" ENSG00000115904 "SOS Ras/Rac guanine nucleotide exchange factor 1" Q07889 2 38981549-39124345 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 226.6;Inhibitory neurons: 224.0;Microglial cells: 161.1;Oligodendrocyte precursor cells: 173.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HMC-1: 134.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005396 Uncertain Approved Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "CAB005396: AB_2270724" "unprognostic (6.68e-2)" "unprognostic (2.12e-2)" "unprognostic (1.01e-1)" "unprognostic (4.14e-3)" "unprognostic (4.02e-2)" "unprognostic (5.14e-2)" "unprognostic (1.74e-3)" "unprognostic (4.55e-2)" "unprognostic (1.10e-1)" "unprognostic (4.13e-2)" "unprognostic (1.24e-2)" "unprognostic (3.18e-2)" "unprognostic (1.38e-2)" "unprognostic (8.96e-3)" "unprognostic (7.61e-2)" "unprognostic (5.59e-2)" "unprognostic (1.33e-2)" 17.5 8.4 8.2 14.8 10.2 10.8 9.8 14.1 10.3 13.1 6.8 11.0 14.7 14.3 10.3 12.3 11.2 13.5 9.5 9.7 10.8 11.0 11.9 11.0 16.9 9.5 10.2 20.1 9.1 17.1 0.1 17.0 9.5 13.4 12.9 13.2 9.0 12.2 13.7 9.4 15.6 13.8 6.7 12.5 11.5 10.3 8.7 15.4 15.1 16.4 17.8 13.5 0.1 10.6 24.8 15.1 22.8 16.2 29.1 35.0 23.8 15.3 18.7 12.0 11.4 16.3 14.6 35.8 10.3 20.1 18.5 14.4 26.9 13.9 22.1 36.3 11.9 55.5 12.8 22.0 11.8 17.9 134.9 21.6 20.5 16.3 15.8 19.5 18.9 8.1 23.9 16.4 15.4 13.5 19.4 15.8 14.3 30.4 10.4 21.5 20.5 10.5 12.1 19.8 22.0 22.0 18.3 32.3 18.2 18.5 10.4 9.3 21.5 19.8 16.0 15.7 15.4 19.3 20.9 18.4 15.8 17.3 12.0 0.0 0.5 1.4 1.3 0.7 1.9 1.6 1.3 1.4 0.4 1.0 1.5 1.4 0.6 2.7 0.9 0.6 0.9 0.4 8.2 10.2 14.1 10.3 9.7 10.8 9.5 10.2 9.5 6.7 8.7 10.6 72.3 16.0 31.2 120.5 20.9 20.8 15.5 10.9 19.9 19.0 18.4 16.9 33.9 18.6 17.8 9.2 10.4 10.2 27.6 19.5 1.9 11.0 64.9 30.0 36.6 43.2 12.0 12.8 226.6 11.9 8.4 22.9 21.4 34.0 3.8 30.0 12.8 18.6 10.3 8.4 224.0 16.9 26.4 19.1 13.2 11.4 22.7 19.9 7.2 161.1 19.6 15.1 26.8 173.4 125.2 14.2 14.6 21.8 37.5 25.3 28.0 12.8 20.4 11.2 6.6 27.1 22.7 11.3 7.0 17.1 25.3 10.4 33.2 18.4 17.0 28.4 SOWAHC "ANKRD57, C2orf26, FLJ21870" ENSG00000198142 "Sosondowah ankyrin repeat domain family member C" Q53LP3 2 109614364-109618990 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 147.6;Granulosa cells: 151.0;Squamous epithelial cells: 137.1;Suprabasal keratinocytes: 199.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 160.4;hTCEpi: 50.8;RT4: 66.2" "Low region specificity" "Detected in all" HPA056131 Enhanced Approved Cytosol No No "Cluster 37: Intestine - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA056131: AB_2683047" "unprognostic (6.76e-2)" "unprognostic (6.96e-2)" "unprognostic (9.61e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.87e-1)" "unprognostic (8.91e-3)" "unprognostic (1.63e-2)" "unprognostic (1.16e-3)" "unprognostic (5.40e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (5.11e-3)" "prognostic favorable (3.56e-5)" "unprognostic (2.30e-1)" "unprognostic (2.28e-1)" "unprognostic (3.50e-1)" "unprognostic (2.54e-2)" 6.3 3.6 2.5 3.5 3.2 0.6 9.4 3.0 2.7 8.0 7.6 11.3 5.1 5.1 3.9 33.3 4.5 8.4 2.0 2.7 4.3 14.0 29.3 7.0 2.9 4.8 6.2 13.0 3.6 5.2 1.9 4.2 4.1 7.0 8.7 5.5 8.3 7.3 1.1 19.3 7.3 6.2 4.0 3.3 5.9 6.5 4.2 4.3 7.9 2.1 7.5 23.1 12.0 4.5 19.3 3.6 10.8 5.9 5.3 8.8 35.1 41.3 24.1 7.1 7.4 17.0 6.0 0.0 16.6 6.3 13.4 18.1 2.5 27.1 7.7 160.4 18.0 0.0 8.6 24.3 4.9 0.0 4.8 4.7 50.8 15.3 10.9 5.9 1.8 0.0 0.3 0.1 5.5 6.4 0.0 1.7 7.6 17.5 16.2 0.0 2.4 0.3 10.7 66.2 13.5 5.8 14.2 2.5 11.3 10.5 5.3 0.4 2.7 5.6 21.6 3.3 3.0 5.3 5.5 0.1 6.6 0.6 13.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 3.2 3.0 2.7 2.7 4.3 4.8 6.2 4.1 4.0 4.2 4.5 18.9 16.0 9.8 2.9 1.2 147.6 43.2 32.0 93.9 15.7 30.5 22.7 3.6 20.0 14.7 12.9 10.4 4.3 0.7 61.1 3.9 15.9 37.8 28.7 21.1 10.8 15.6 2.7 0.2 7.1 28.6 15.6 13.3 76.9 0.0 151.0 6.8 53.2 8.0 0.0 1.2 32.7 10.2 7.0 15.1 13.7 11.8 6.2 19.6 0.0 3.4 7.3 2.1 1.5 2.4 14.2 34.2 15.1 0.6 21.0 21.5 25.1 5.5 20.7 13.1 12.1 20.8 20.8 13.2 137.1 199.3 10.0 2.2 5.3 36.7 80.9 SPAG1 "CILD28, CT140, FLJ32920, HSD-3.8, SP75, TPIS" ENSG00000104450 "Sperm associated antigen 1" Q07617 8 100157906-100259278 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Fertilization Hydrolase "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 96.0;Endometrial ciliated cells: 190.6;Respiratory ciliated cells: 198.6;Spermatocytes: 91.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023748, HPA053682" Enhanced Supported Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA023748: AB_2671304, HPA053682: AB_2682229" "unprognostic (9.95e-2)" "unprognostic (5.37e-2)" "unprognostic (1.38e-2)" "unprognostic (4.24e-2)" "unprognostic (1.46e-1)" "unprognostic (2.57e-1)" "unprognostic (5.86e-2)" "unprognostic (9.19e-2)" "unprognostic (1.53e-1)" "unprognostic (5.62e-2)" "unprognostic (1.57e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.87e-4)" "unprognostic (9.11e-3)" "unprognostic (8.83e-3)" "unprognostic (1.54e-1)" "prognostic favorable (2.62e-4)" 1.8 1.3 3.0 3.6 3.2 10.1 3.0 4.2 3.0 5.4 14.0 12.9 2.9 2.4 1.5 7.8 10.0 3.7 1.5 3.0 4.6 3.2 4.7 5.0 2.7 7.2 9.0 1.0 2.5 9.0 5.7 1.8 6.2 3.1 18.3 1.9 4.6 3.5 0.4 7.9 2.7 1.8 6.0 2.0 6.3 19.4 4.8 2.1 3.4 0.6 4.4 5.3 3.0 5.4 31.3 8.3 0.5 1.8 1.8 1.5 4.6 5.7 3.4 6.8 7.1 8.3 13.5 1.2 20.0 1.8 10.1 16.1 5.9 11.1 6.3 18.1 6.1 5.2 9.0 3.1 2.4 1.4 4.5 1.3 5.8 8.4 6.6 5.3 5.8 5.7 0.2 16.1 1.0 11.2 3.1 1.4 0.5 15.6 9.1 0.5 1.3 4.7 26.1 14.8 4.8 3.5 7.8 6.4 7.0 2.2 9.2 5.9 5.3 6.8 9.8 3.6 14.9 10.9 8.9 0.9 6.5 5.0 3.4 0.0 0.1 0.6 0.1 0.0 0.0 0.8 0.1 0.1 0.1 0.3 0.0 0.1 0.7 1.0 0.2 0.2 0.0 0.0 3.0 3.2 4.2 3.0 3.0 4.6 7.2 9.0 6.2 6.0 4.8 5.4 7.7 48.1 22.8 18.9 7.7 5.6 9.6 18.1 2.2 2.0 13.3 7.7 5.6 22.8 37.2 18.4 0.0 1.3 19.0 32.9 5.9 19.7 96.0 190.6 7.1 6.9 22.1 0.4 30.1 8.6 8.7 5.0 22.4 39.5 10.1 7.3 4.2 8.0 2.8 8.4 21.6 14.9 6.1 2.2 5.3 32.3 5.0 3.9 1.8 6.5 4.5 11.5 5.2 4.5 4.1 14.9 17.7 3.8 15.9 10.3 2.4 10.0 198.6 2.3 0.0 4.8 6.4 91.9 4.7 2.9 5.4 2.3 12.0 1.3 20.1 23.3 SPATA5 "AFG2, SPAF" ENSG00000145375 "Spermatogenesis associated 5" Q8NB90 4 122923070-123319433 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Chaperone, Developmental protein, Hydrolase" "Deafness, Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 207.9;Inhibitory neurons: 59.0;Microglial cells: 104.0;Oligodendrocyte precursor cells: 79.9;Oligodendrocytes: 91.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036450, HPA036451" Approved Approved Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol "HPA036450: AB_2675131, HPA036451: AB_10670107" "unprognostic (4.28e-1)" "unprognostic (7.54e-2)" "unprognostic (7.37e-3)" "unprognostic (1.26e-1)" "unprognostic (5.16e-1)" "unprognostic (1.18e-1)" "unprognostic (7.65e-4)" "unprognostic (1.95e-3)" "unprognostic (9.00e-2)" "unprognostic (2.78e-1)" "unprognostic (4.43e-3)" "unprognostic (4.62e-2)" "unprognostic (1.26e-2)" "unprognostic (1.52e-1)" "unprognostic (5.68e-1)" "unprognostic (2.63e-2)" "unprognostic (1.79e-1)" 1.3 0.8 0.8 0.9 1.1 1.4 1.6 2.3 1.0 1.3 1.2 1.0 0.6 1.3 0.8 1.0 1.0 0.8 0.9 0.6 1.2 1.1 1.1 0.9 1.2 1.2 1.1 1.2 0.8 1.5 0.7 1.4 1.2 1.1 1.2 2.2 1.0 1.1 1.3 1.2 0.7 1.3 1.0 1.3 2.3 3.6 1.0 2.0 1.5 1.2 1.2 1.0 1.1 1.3 2.3 3.2 2.9 7.1 2.4 1.7 1.9 4.0 1.6 3.3 3.3 1.5 3.2 3.7 2.4 2.4 2.4 2.0 5.0 2.2 5.6 6.2 0.9 3.8 5.7 2.5 1.1 5.2 4.0 1.2 1.1 3.8 3.3 1.7 3.4 2.4 7.7 6.2 4.6 2.4 10.1 3.2 2.1 3.6 1.3 3.3 7.2 2.4 1.9 1.9 4.8 3.1 3.2 2.3 1.7 4.2 2.2 2.0 2.6 6.9 5.2 4.6 4.2 3.9 5.0 3.3 3.3 4.4 6.2 0.5 0.2 0.2 0.6 0.6 0.4 0.5 0.5 0.5 0.1 0.5 0.5 0.5 0.3 0.5 0.2 0.7 0.3 0.2 0.8 1.1 2.3 1.0 0.6 1.2 1.2 1.1 1.2 1.0 1.0 1.3 10.7 16.0 5.0 34.6 9.1 5.1 5.6 2.6 6.2 6.2 4.2 3.2 4.3 11.5 7.4 1.8 14.6 5.1 6.7 2.9 0.0 3.1 207.9 4.5 9.6 8.5 2.4 11.2 48.8 3.6 4.3 5.1 14.3 5.2 5.1 8.6 4.2 3.2 3.5 3.3 59.0 2.6 0.0 4.1 5.3 25.0 7.2 5.3 0.0 104.0 1.8 4.0 4.1 79.9 91.4 4.2 2.1 4.5 10.6 3.9 1.5 3.1 6.4 11.3 0.0 12.5 6.6 14.7 10.6 5.0 5.4 2.2 9.9 4.7 4.1 3.0 SPATS2 "FLJ13117, SCR59, SPATA10" ENSG00000123352 "Spermatogenesis associated serine rich 2" Q86XZ4 12 49366584-49527425 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 144.8;Spermatogonia: 138.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "B-cells: 6.0;dendritic cells: 8.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038642, HPA038643, HPA076823" Uncertain Enhanced Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "HPA038642: AB_2676128, HPA038643: AB_10672523, HPA076823: " "unprognostic (2.87e-2)" "unprognostic (2.63e-1)" "unprognostic (2.20e-2)" "unprognostic (1.89e-1)" "unprognostic (5.56e-2)" "unprognostic (6.33e-2)" "prognostic unfavorable (9.57e-8)" "unprognostic (4.55e-2)" "unprognostic (6.32e-2)" "prognostic favorable (1.44e-4)" "unprognostic (2.64e-1)" "unprognostic (1.71e-1)" "prognostic unfavorable (5.20e-4)" "unprognostic (9.51e-2)" "unprognostic (1.16e-1)" "unprognostic (2.57e-1)" "unprognostic (4.81e-1)" 7.7 7.8 9.1 10.3 11.0 6.5 9.4 15.3 12.8 12.8 10.9 11.0 11.6 11.1 7.9 6.8 6.9 11.1 7.1 11.5 6.2 9.6 4.8 8.0 15.7 10.7 7.8 8.0 12.2 21.5 13.8 8.9 11.1 9.9 11.5 10.1 18.4 6.1 11.1 16.3 10.3 11.3 4.4 10.8 13.1 26.1 8.1 13.2 12.9 6.4 18.1 10.3 13.1 10.4 17.9 39.7 33.2 38.7 19.1 29.3 10.7 20.8 29.8 34.2 29.6 36.0 39.0 44.4 47.5 18.4 22.5 20.8 28.9 39.1 43.8 33.9 17.2 40.4 28.2 29.1 34.7 11.1 23.1 25.6 19.0 53.8 50.9 111.8 82.0 19.8 21.7 38.9 35.2 32.3 22.7 16.5 34.2 29.0 40.1 32.7 56.5 53.4 31.9 22.5 37.2 33.4 45.4 28.6 49.0 20.4 49.2 12.0 75.7 15.1 36.5 13.5 13.2 52.4 65.7 37.5 19.7 18.6 22.0 1.6 1.3 0.3 1.7 0.4 1.7 6.0 1.4 1.0 4.1 3.2 1.2 1.0 0.9 1.3 0.3 8.0 1.1 1.1 9.1 11.0 15.3 12.8 11.5 6.2 10.7 7.8 11.1 4.4 8.1 10.4 35.0 19.2 19.8 34.6 33.8 58.0 48.8 52.0 25.0 44.5 29.9 29.8 9.9 35.8 19.6 36.8 22.9 9.7 19.2 9.6 5.9 26.0 77.4 28.3 63.1 44.6 36.6 22.7 114.0 27.9 12.0 34.8 23.0 45.1 10.8 37.1 29.3 5.6 8.0 42.1 67.6 21.6 20.3 9.2 39.8 46.3 31.7 15.3 19.6 27.2 15.0 22.3 16.5 59.3 30.6 46.4 11.7 33.4 144.8 36.4 13.3 12.4 10.1 5.9 52.6 20.5 27.7 137.3 138.1 17.0 60.4 5.3 16.2 31.5 30.2 29.4 SPC25 "AD024, MGC22228, SPBC25" ENSG00000152253 "SPC25 component of NDC80 kinetochore complex" Q9HBM1 2 168834132-168913371 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 23.5;Erythroid cells: 29.9;Extravillous trophoblasts: 37.9;Muller glia cells: 17.2;Spermatocytes: 26.2;Spermatogonia: 20.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047144, HPA050544" Enhanced Enhanced Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA047144: AB_2679952, HPA050544: " "unprognostic (3.52e-2)" "unprognostic (2.28e-2)" "unprognostic (2.23e-1)" "prognostic unfavorable (8.61e-5)" "unprognostic (3.15e-1)" "unprognostic (1.84e-2)" "prognostic unfavorable (4.74e-6)" "prognostic unfavorable (9.44e-5)" "unprognostic (1.84e-3)" "unprognostic (7.58e-2)" "unprognostic (1.36e-1)" "unprognostic (1.30e-2)" "unprognostic (1.11e-16)" "unprognostic (9.91e-3)" "unprognostic (1.85e-1)" "unprognostic (3.43e-1)" "unprognostic (1.57e-1)" 0.6 0.8 0.6 0.7 0.6 4.2 1.0 0.3 1.5 0.7 0.5 2.1 3.7 0.5 0.0 4.4 0.3 0.5 0.4 1.6 0.7 1.1 0.8 0.9 3.9 0.6 0.7 0.5 1.3 0.1 0.1 1.1 0.8 0.4 1.6 1.7 1.0 0.0 0.6 1.1 2.1 1.0 0.1 2.1 1.6 3.4 0.6 8.5 0.2 0.1 3.7 0.5 1.5 1.8 1.0 16.8 40.6 22.8 1.8 1.9 14.5 22.9 9.3 23.5 18.1 5.6 16.2 15.7 9.0 3.4 31.9 20.9 15.9 0.0 20.7 10.0 21.5 30.2 7.2 2.2 0.1 20.3 8.9 0.3 1.0 14.3 0.0 4.7 10.3 28.2 0.8 15.7 6.4 9.8 16.1 26.3 0.9 11.2 21.0 28.8 38.1 5.6 9.6 13.7 30.4 0.5 16.8 14.4 3.9 13.5 0.4 16.4 2.5 3.6 42.1 13.4 18.2 31.4 56.0 12.5 4.1 0.5 14.3 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.1 0.6 0.6 0.3 1.5 1.6 0.7 0.6 0.7 0.8 0.1 0.6 1.8 0.4 0.0 1.1 0.7 4.2 5.4 1.5 7.1 1.2 0.0 1.5 2.4 0.6 0.0 2.6 0.0 0.0 23.5 1.5 3.7 0.0 0.2 2.0 0.5 1.8 1.6 0.0 29.9 0.3 0.0 37.9 4.6 2.0 1.8 0.0 10.1 2.9 1.2 15.1 0.0 0.5 5.2 2.0 1.9 2.4 1.6 0.6 2.0 0.0 0.0 0.0 17.2 0.0 5.0 0.2 0.5 0.1 1.2 15.3 1.0 1.0 0.2 0.1 0.6 0.0 1.3 4.4 26.2 20.1 7.3 1.4 5.7 2.7 1.7 9.9 2.5 SPDL1 "CCDC99, FLJ20364, hSpindly" ENSG00000040275 "Spindle apparatus coiled-coil protein 1" Q96EA4 5 169583636-169604778 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 35.5" "Cell type enhanced" "Detected in many" "Granulosa cells: 38.4;Spermatocytes: 112.9;Spermatogonia: 59.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA044700, HPA048146" Enhanced Approved Cytosol NA Yes "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA044700: AB_2679052, HPA048146: AB_2680284" "unprognostic (2.61e-2)" "unprognostic (1.94e-1)" "unprognostic (8.59e-3)" "prognostic unfavorable (1.18e-4)" "unprognostic (4.24e-1)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.48e-6)" "unprognostic (2.63e-3)" "unprognostic (5.70e-3)" "unprognostic (8.27e-3)" "prognostic unfavorable (1.19e-5)" "unprognostic (2.92e-2)" "prognostic unfavorable (2.13e-6)" "unprognostic (2.81e-1)" "unprognostic (3.13e-1)" "unprognostic (3.28e-2)" "unprognostic (2.93e-1)" 3.9 3.6 5.5 9.4 6.0 10.9 5.5 6.1 7.2 3.4 3.4 5.4 5.7 6.2 3.8 5.8 4.4 4.5 3.4 4.7 5.6 4.8 3.2 4.0 14.9 6.0 5.5 6.7 2.5 5.0 2.4 8.4 6.1 3.3 5.7 3.4 3.2 3.1 5.3 5.5 5.3 7.4 7.1 6.6 5.3 35.5 5.4 21.5 4.3 5.9 14.0 4.8 3.8 7.2 57.0 69.2 67.4 47.6 17.6 18.5 59.1 181.1 22.9 128.1 119.0 89.6 38.8 54.3 116.9 147.0 90.3 39.3 56.8 76.0 139.6 58.1 65.2 59.6 117.0 36.2 8.3 66.9 51.3 9.2 6.2 62.2 34.0 29.0 59.9 60.5 41.3 39.3 142.4 58.5 54.1 28.2 50.1 28.9 63.2 64.8 67.6 38.5 89.7 19.8 43.7 31.4 84.9 23.6 34.5 46.9 27.0 44.9 46.3 146.6 46.8 43.4 140.0 30.1 69.2 69.1 35.4 61.9 50.2 4.0 2.7 3.8 8.4 3.6 8.9 11.2 7.9 8.9 2.8 12.7 10.8 9.1 0.5 8.4 6.2 19.7 8.6 4.1 5.5 6.0 6.1 7.2 4.7 5.6 6.0 5.5 6.1 7.1 5.4 7.2 6.1 3.2 6.3 3.9 8.7 4.0 1.7 4.8 4.6 6.9 6.2 7.5 7.1 2.8 7.0 1.8 0.0 14.1 9.8 3.6 5.9 6.6 9.6 5.3 8.0 6.5 1.8 22.3 6.2 4.8 26.1 7.7 12.2 4.9 8.8 38.4 13.2 3.2 12.2 3.3 6.5 3.2 2.0 4.7 3.6 11.1 4.4 4.7 3.6 2.8 5.0 7.4 13.4 5.0 6.8 6.6 1.9 6.4 10.2 1.6 0.5 8.2 4.1 4.4 6.6 6.4 9.9 112.9 59.2 5.8 4.4 4.9 5.2 9.6 7.4 2.5 SPTB ENSG00000070182 "Spectrin beta, erythrocytic" P11277 14 64746283-64879907 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Disease variant, Elliptocytosis, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 62.5;skeletal muscle: 123.9;tongue: 69.8" "Cell type enhanced" "Detected in some" "Erythroid cells: 81.0;Excitatory neurons: 16.0;Horizontal cells: 16.8;Inhibitory neurons: 32.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HEL: 39.2;K-562: 47.8;U-937: 14.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003394, HPA003398, CAB015169, CAB016232" Enhanced Approved Cytosol NA NA 7800000 "Cluster 80: Striated muscle - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 37: Myocytes - Muscle contraction" Cytosol "CAB015169: AB_2194363, CAB016232: AB_785785, HPA003394: AB_1080076, HPA003398: AB_1080074" "unprognostic (2.69e-1)" "unprognostic (4.72e-1)" "unprognostic (3.04e-2)" "unprognostic (2.19e-3)" "unprognostic (1.71e-1)" "unprognostic (2.33e-2)" "unprognostic (1.49e-1)" "unprognostic (1.30e-3)" "unprognostic (2.66e-1)" "unprognostic (2.28e-2)" "unprognostic (1.55e-3)" "unprognostic (2.11e-1)" "unprognostic (2.65e-1)" "unprognostic (1.39e-2)" "unprognostic (2.97e-1)" "unprognostic (3.44e-2)" "unprognostic (2.18e-2)" 2.2 1.5 5.3 0.2 11.2 62.5 0.3 28.3 11.4 0.3 27.7 0.2 0.1 0.2 5.2 2.0 0.5 0.4 22.7 10.8 4.0 1.0 0.1 0.4 0.0 28.5 5.3 0.2 2.6 11.1 5.3 6.7 28.2 1.5 0.1 1.6 2.2 1.1 123.9 0.2 0.2 0.8 8.5 0.8 0.2 0.7 9.3 0.4 0.1 69.8 0.0 0.2 0.2 4.4 0.3 1.5 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.1 0.0 0.7 0.0 0.0 0.0 0.3 0.3 2.3 6.3 0.2 0.0 0.4 3.7 39.2 0.3 0.0 0.0 0.0 0.7 0.1 0.1 0.0 0.0 0.0 0.0 1.4 47.8 0.0 0.0 0.3 0.0 0.3 0.0 0.5 2.1 0.0 0.0 0.2 0.0 0.2 6.1 2.6 0.0 0.0 0.0 0.2 0.1 0.5 0.0 0.3 6.7 0.0 0.6 1.5 7.7 0.0 0.1 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 5.3 11.2 28.3 11.4 10.8 4.0 28.5 5.3 28.2 8.5 9.3 4.4 0.1 0.0 0.0 0.7 0.0 0.8 0.7 0.6 0.0 10.3 0.5 0.1 6.3 1.5 0.7 0.0 0.0 0.1 0.5 0.0 0.0 0.3 0.4 0.4 0.9 0.4 3.0 81.0 16.0 0.2 0.3 0.8 0.0 0.9 2.5 0.2 0.0 0.0 0.2 16.8 32.1 0.3 0.0 0.0 0.4 0.4 0.3 0.3 1.8 1.9 0.0 5.0 1.0 11.1 2.1 0.3 0.0 1.2 0.1 0.7 0.0 0.2 0.0 2.6 6.6 11.6 3.8 0.1 1.1 0.5 0.4 0.1 0.6 0.4 0.1 0.6 SRGAP1 "ARHGAP13, KIAA1304" ENSG00000196935 "SLIT-ROBO Rho GTPase activating protein 1" Q7Z6B7 12 63844700-64162217 "Disease related genes, Predicted intracellular proteins" "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 159.0;Early spermatids: 192.4;Microglial cells: 151.8;Muller glia cells: 136.2;Oligodendrocyte precursor cells: 159.8;Oligodendrocytes: 135.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 30.4;hTERT-HME1: 46.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052416, HPA078079" Uncertain Approved Cytosol NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 30: Epithelial cell lines - Translation" "Cluster 5: Muller glia cells - Visual perception" Cytosol "HPA052416: AB_2681824, HPA078079: " "unprognostic (3.05e-3)" "unprognostic (2.28e-1)" "unprognostic (1.58e-2)" "unprognostic (2.22e-3)" "unprognostic (2.24e-1)" "unprognostic (1.12e-1)" "unprognostic (2.34e-2)" "unprognostic (1.45e-3)" "unprognostic (1.43e-2)" "prognostic unfavorable (5.67e-4)" "unprognostic (3.54e-3)" "unprognostic (8.56e-2)" "unprognostic (1.41e-3)" "unprognostic (8.16e-2)" "unprognostic (2.08e-1)" "unprognostic (8.31e-2)" "unprognostic (1.56e-2)" 4.0 3.7 5.5 1.8 8.9 0.4 3.9 7.9 4.3 4.9 0.8 3.0 1.4 4.3 1.4 2.9 3.6 2.4 2.1 4.0 8.3 3.0 0.8 6.2 1.0 11.6 12.0 4.7 4.8 6.5 1.4 1.9 9.2 2.3 2.6 6.1 4.6 0.9 1.6 1.9 2.5 2.5 7.7 2.4 1.9 3.9 10.4 0.7 4.4 1.0 0.9 2.8 3.3 7.2 5.3 11.2 17.6 1.7 13.3 23.2 3.7 16.4 14.7 6.0 5.2 5.9 4.3 0.1 6.6 30.4 14.9 3.3 1.5 9.4 6.1 4.2 1.7 0.2 7.9 6.0 16.4 0.1 0.2 21.6 8.8 16.8 46.8 8.2 5.5 0.3 0.1 0.2 8.0 3.2 0.1 0.1 1.5 2.8 6.5 0.1 3.3 0.1 7.4 2.8 2.8 5.3 6.5 6.7 4.4 2.8 1.8 0.1 11.8 12.4 2.3 13.2 7.6 0.1 0.1 0.1 10.4 1.3 5.0 0.4 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.4 0.2 0.1 0.1 0.0 0.0 5.5 8.9 7.9 4.3 4.0 8.3 11.6 12.0 9.2 7.7 10.4 7.2 19.1 0.0 3.3 159.0 3.5 7.8 53.3 20.4 0.0 7.8 19.7 15.1 6.4 37.1 21.7 9.2 6.2 31.7 0.9 42.5 11.7 37.3 192.4 8.3 33.3 24.8 16.7 0.0 19.6 26.0 8.6 43.5 26.0 26.0 1.3 26.8 25.0 2.0 12.2 3.3 38.4 26.6 44.7 34.3 22.2 58.4 22.1 43.5 17.8 151.8 25.1 136.2 0.0 159.8 135.8 41.7 39.8 15.8 0.8 50.5 5.2 14.7 22.1 8.1 0.0 55.1 19.7 5.5 29.1 11.6 3.8 7.3 3.6 2.0 19.6 50.7 SRGAP2B SRGAP2P2 ENSG00000196369 "SLIT-ROBO Rho GTPase activating protein 2B" P0DMP2 1 144887265-145095528 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 48.7" "Cell type enriched" "Detected in many" 4 "Microglial cells: 239.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 3.6;granulocytes: 3.9;monocytes: 7.9" "Low cell line specificity" "Detected in all" HPA078079 Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 12: NES - Nervous system development" "Cluster 41: Macrophages - Immune response" Cytosol "HPA078079: " "unprognostic (1.13e-2)" "unprognostic (2.76e-1)" "unprognostic (1.48e-3)" "unprognostic (3.52e-3)" "unprognostic (1.66e-2)" "unprognostic (1.01e-1)" "unprognostic (3.49e-2)" "unprognostic (4.60e-2)" "unprognostic (3.13e-1)" "unprognostic (2.89e-2)" "unprognostic (7.27e-2)" "unprognostic (1.88e-1)" "unprognostic (2.16e-5)" "unprognostic (3.12e-1)" "unprognostic (5.43e-1)" "unprognostic (8.54e-2)" "unprognostic (2.38e-1)" 9.3 10.5 9.9 6.8 9.2 7.7 6.1 48.7 10.3 6.3 3.7 4.7 2.8 6.2 4.2 5.7 6.7 5.7 5.1 10.3 10.5 8.0 4.2 8.6 5.6 15.4 14.4 8.6 3.6 13.1 3.0 10.8 19.4 3.7 2.8 3.7 3.3 4.6 8.9 18.9 3.5 7.1 14.9 12.4 2.9 3.5 12.4 6.4 4.3 5.8 3.7 5.0 6.4 17.1 13.4 28.5 60.3 12.5 28.3 24.3 19.0 14.6 12.8 12.2 14.0 8.7 24.1 6.7 19.1 8.7 21.7 22.8 15.6 8.5 15.0 6.3 15.8 9.8 20.6 12.1 19.8 8.8 12.5 17.3 12.6 30.1 26.4 18.4 24.8 5.7 5.3 23.1 6.7 15.1 3.8 10.3 11.2 6.7 10.2 10.3 12.9 11.6 10.5 5.8 7.5 9.5 19.3 6.9 31.6 14.9 14.4 22.1 45.3 26.1 26.7 23.3 17.1 9.6 12.7 4.1 9.5 11.6 37.7 1.2 3.8 0.5 0.6 5.4 0.5 0.9 1.0 1.2 2.7 0.9 0.6 0.7 3.9 0.4 7.9 3.6 1.1 0.9 9.9 9.2 48.7 10.3 10.3 10.5 15.4 14.4 19.4 14.9 12.4 17.1 37.3 25.6 7.7 5.5 14.0 0.0 3.5 0.0 6.8 17.6 3.1 3.4 3.3 5.7 2.5 9.2 2.1 4.7 20.3 0.5 0.0 6.8 1.1 13.8 14.0 35.1 2.4 29.3 37.5 3.0 21.5 15.3 3.1 6.0 1.3 3.3 54.3 4.3 12.9 0.0 55.6 2.0 0.0 58.7 0.0 2.7 15.2 40.1 0.0 239.8 38.4 8.1 16.5 24.6 9.5 6.0 0.2 9.8 8.4 4.8 0.8 1.2 8.0 2.9 6.6 16.9 12.3 4.5 6.9 19.9 0.0 2.9 6.9 8.6 1.8 4.2 SRGAP2C SRGAP2P1 ENSG00000171943 "SLIT-ROBO Rho GTPase activating protein 2C" P0DJJ0 1 121184811-121392874 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 31.2" "Cell type enhanced" "Detected in many" "Microglial cells: 180.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "WM-115: 80.0" HPA078079 Approved Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 17: WM-115 - Nervous system development" "Cluster 41: Macrophages - Immune response" Cytosol "HPA078079: " "unprognostic (2.43e-1)" "unprognostic (6.66e-2)" "unprognostic (7.65e-3)" "unprognostic (1.48e-6)" "unprognostic (2.40e-2)" "unprognostic (1.11e-1)" "unprognostic (7.18e-4)" "unprognostic (6.10e-2)" "unprognostic (7.48e-2)" "unprognostic (2.32e-1)" "unprognostic (1.36e-2)" "unprognostic (2.89e-1)" "unprognostic (3.71e-7)" "unprognostic (4.90e-2)" "unprognostic (2.10e-1)" "unprognostic (1.70e-1)" "unprognostic (7.66e-2)" 8.3 6.5 11.1 3.7 13.2 7.2 5.7 31.2 12.5 5.8 3.9 6.5 2.1 5.4 2.2 4.3 5.0 4.6 5.8 11.7 11.8 7.1 4.7 7.3 4.6 16.1 12.3 6.8 2.2 13.7 3.3 8.0 17.6 3.6 2.8 3.5 3.0 4.6 2.8 15.5 3.6 6.0 16.6 10.7 3.2 1.5 12.4 4.2 3.9 10.7 3.4 4.6 5.5 21.9 11.1 14.1 30.7 6.8 23.1 20.1 16.8 12.3 9.8 10.2 13.2 0.2 11.0 7.0 10.8 16.8 7.3 5.9 11.0 8.9 13.4 9.2 11.2 10.0 24.5 11.1 13.3 6.8 11.4 15.2 8.9 13.1 16.6 11.6 24.5 4.3 9.3 12.8 7.6 6.6 4.3 8.6 9.7 3.5 6.7 6.2 35.9 6.2 9.7 6.5 5.9 3.8 21.2 7.5 38.6 15.8 9.5 19.8 21.9 19.1 18.7 28.9 18.1 7.3 5.6 4.2 16.7 13.7 80.0 0.3 3.4 0.6 1.1 2.8 0.7 0.9 1.3 1.2 2.5 0.9 0.6 0.8 3.2 0.6 5.3 2.4 1.3 0.9 11.1 13.2 31.2 12.5 11.7 11.8 16.1 12.3 17.6 16.6 12.4 21.9 39.9 54.5 11.5 5.2 14.4 0.0 5.6 0.0 6.2 14.2 5.8 6.7 4.3 15.7 5.0 11.0 2.1 5.5 15.5 1.2 1.9 10.9 1.0 11.7 15.4 34.6 2.4 29.7 42.0 5.0 24.8 15.9 5.1 6.4 6.3 7.8 55.3 8.7 19.9 0.0 62.6 2.7 0.0 64.2 0.0 2.1 19.6 41.6 0.0 180.8 39.6 8.4 18.6 35.2 27.4 7.2 1.4 25.6 10.7 5.0 0.5 1.0 8.7 4.3 32.9 20.2 14.5 10.1 10.8 12.5 0.0 2.5 12.6 7.0 2.0 4.5 SRGAP3 "ARHGAP14, KIAA0411, MEGAP, SRGAP2, WRP" ENSG00000196220 "SLIT-ROBO Rho GTPase activating protein 3" O43295 3 8980591-9363053 "Disease related genes, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.1;retina: 14.8" "Cell type enhanced" "Detected in many" "Astrocytes: 201.8;Bipolar cells: 217.5;Cone photoreceptor cells: 273.1;Endometrial ciliated cells: 166.0;Excitatory neurons: 223.1;Horizontal cells: 228.8;Inhibitory neurons: 281.2;Oligodendrocyte precursor cells: 159.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.3;HBEC3-KT: 8.2;hTCEpi: 7.8;RT4: 10.9;T-47d: 10.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036959, HPA044074, HPA078079" Enhanced Approved Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 62: Horizontal cells - Visual perception" Cytosol "HPA036959: AB_10672784, HPA044074: AB_2678799, HPA078079: " "unprognostic (3.63e-3)" "unprognostic (1.12e-3)" "unprognostic (7.61e-2)" "unprognostic (1.84e-1)" "unprognostic (1.11e-1)" "unprognostic (3.53e-1)" "unprognostic (1.49e-1)" "unprognostic (1.80e-2)" "unprognostic (9.55e-2)" "unprognostic (6.66e-3)" "unprognostic (2.70e-2)" "unprognostic (5.58e-2)" "unprognostic (1.18e-3)" "unprognostic (6.10e-2)" "unprognostic (3.77e-1)" "unprognostic (2.75e-2)" "unprognostic (6.39e-3)" 0.7 3.3 12.3 0.7 13.9 0.3 1.5 22.1 16.9 5.2 0.3 1.0 0.7 2.2 1.5 2.3 10.9 1.0 1.8 14.5 9.1 3.2 0.5 1.0 1.1 5.1 9.8 3.7 1.1 0.6 6.1 0.7 7.4 4.5 1.1 14.8 4.2 1.4 1.3 3.7 0.9 0.7 5.6 0.7 1.5 3.5 11.9 1.8 2.6 2.1 0.9 4.1 1.7 10.0 0.5 0.5 9.3 0.4 0.6 1.2 1.3 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.4 0.0 0.1 4.8 0.2 8.2 0.1 0.0 0.6 0.0 0.2 0.0 0.0 0.0 5.0 0.7 7.8 0.6 0.8 0.2 0.0 2.1 0.0 0.0 0.0 0.1 0.2 2.0 0.9 1.6 0.7 1.1 0.0 0.0 3.8 10.9 1.0 1.2 0.2 2.8 0.1 2.2 10.5 0.0 0.0 0.0 0.3 0.1 0.1 2.7 0.1 0.0 0.8 1.7 0.3 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 12.3 13.9 22.1 16.9 14.5 9.1 5.1 9.8 7.4 5.6 11.9 10.0 1.0 3.2 5.6 201.8 2.3 4.1 28.7 36.3 23.3 217.5 7.9 9.8 9.6 0.0 40.6 77.3 273.1 2.4 3.5 1.4 5.9 3.2 24.1 166.0 6.0 4.2 3.0 0.8 223.1 0.5 0.8 4.9 8.2 93.8 1.3 5.4 0.7 2.1 13.2 228.8 281.2 6.2 12.2 18.6 6.0 20.2 2.5 9.4 1.8 37.5 3.3 80.6 1.0 159.8 132.2 0.6 0.5 1.2 1.4 12.3 0.5 1.4 59.4 94.8 0.0 2.9 3.9 6.1 7.1 17.2 5.8 1.4 14.7 12.0 3.1 31.2 SRP54 ENSG00000100883 "Signal recognition particle 54" P61011 14 34981957-35029686 "Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Hydrolase, Ribonucleoprotein, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 327.3;Late spermatids: 901.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048977, HPA062044" Approved Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA048977: AB_2680583, HPA062044: AB_2684668" "unprognostic (1.22e-3)" "unprognostic (6.04e-2)" "unprognostic (9.06e-2)" "unprognostic (1.72e-2)" "unprognostic (3.88e-1)" "unprognostic (2.67e-3)" "unprognostic (2.06e-3)" "unprognostic (6.44e-2)" "unprognostic (2.53e-1)" "unprognostic (1.88e-2)" "unprognostic (2.15e-1)" "unprognostic (1.66e-1)" "unprognostic (1.10e-3)" "unprognostic (1.81e-1)" "unprognostic (1.98e-1)" "unprognostic (2.86e-1)" "unprognostic (2.50e-3)" 22.8 33.1 17.1 30.2 18.1 17.4 28.7 19.3 22.5 32.5 20.9 28.1 25.8 23.3 35.8 28.5 22.0 23.2 32.1 17.6 21.3 35.3 61.9 25.0 34.6 19.8 19.2 22.7 55.0 39.7 36.2 29.5 20.5 31.2 29.5 24.2 60.3 28.7 39.8 26.1 26.8 23.5 20.0 28.4 30.4 44.0 18.1 35.5 30.9 33.7 42.6 34.8 23.1 21.4 59.3 66.9 56.7 54.9 62.8 61.3 67.8 83.2 78.3 87.3 107.0 71.3 62.8 75.8 77.5 81.4 75.8 56.1 79.0 66.7 125.6 87.5 37.8 70.9 54.6 184.6 92.7 70.5 65.4 51.5 64.8 63.5 102.3 66.1 88.8 64.9 61.7 82.7 93.1 98.8 81.9 42.4 45.0 96.1 61.3 58.5 72.2 67.4 104.9 89.3 48.9 59.4 59.3 76.7 74.6 71.4 99.4 49.7 66.6 48.7 51.0 62.8 57.1 73.2 108.3 101.1 36.8 45.9 63.5 23.8 27.4 39.2 31.0 35.0 39.6 25.6 31.4 34.0 32.8 25.8 28.7 28.3 27.1 42.1 47.0 21.9 48.2 30.5 17.1 18.1 19.3 22.5 17.6 21.3 19.8 19.2 20.5 20.0 18.1 21.4 40.8 12.8 49.3 25.5 63.2 40.0 56.0 74.6 37.5 37.5 40.7 29.0 41.0 34.3 81.2 40.5 58.4 67.3 59.6 39.4 64.6 73.2 327.3 53.1 43.9 40.7 44.9 36.2 25.4 79.8 75.6 45.8 38.7 64.3 47.5 37.3 36.4 110.0 49.7 26.9 26.8 48.7 87.5 39.0 43.6 901.8 38.5 47.4 28.4 24.4 56.1 44.3 41.2 27.6 54.6 55.1 34.0 37.6 133.1 60.7 39.0 79.2 93.0 50.1 26.3 38.3 46.1 95.4 76.0 36.0 50.3 94.0 64.7 43.0 31.6 64.5 SRP68 ENSG00000167881 "Signal recognition particle 68" Q9UHB9 17 76038775-76072517 "Plasma proteins, Predicted intracellular proteins, Transporters" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 314.6" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 162.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "medulla oblongata: 314.6" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023303, HPA055617" Approved Supported Cytosol NA NA 23000 "Cluster 26: Non-specific - Mitochondria" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA023303: AB_1857477, HPA055617: AB_2682863" "unprognostic (1.25e-1)" "unprognostic (8.97e-2)" "unprognostic (3.47e-2)" "unprognostic (1.46e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (2.18e-4)" "prognostic unfavorable (4.28e-5)" "unprognostic (3.31e-2)" "unprognostic (8.31e-2)" "unprognostic (1.62e-2)" "unprognostic (1.11e-1)" "unprognostic (4.10e-2)" "unprognostic (4.42e-2)" "unprognostic (8.73e-2)" "unprognostic (4.75e-2)" "prognostic favorable (2.65e-4)" "unprognostic (4.02e-3)" 37.5 34.6 23.7 24.8 25.2 21.9 36.3 25.5 76.6 39.4 24.6 47.2 21.3 39.7 35.1 49.8 37.4 17.3 42.8 34.8 27.7 31.6 37.0 34.0 29.0 314.6 25.1 39.8 65.7 37.7 37.7 33.1 49.6 30.6 27.4 28.0 38.5 26.1 103.1 43.7 32.2 34.5 30.5 31.5 41.5 22.2 25.9 30.8 32.8 47.0 36.7 41.9 37.9 26.4 98.0 89.8 51.0 54.9 71.5 57.2 94.3 72.4 50.7 80.7 62.9 75.5 45.5 81.6 36.8 70.5 69.2 66.2 98.2 74.2 119.2 34.3 118.1 72.6 63.4 102.8 86.3 83.9 54.7 48.5 81.3 70.7 61.1 60.0 95.1 47.4 109.0 70.9 67.2 60.1 84.6 43.5 50.3 81.2 91.0 70.1 137.1 79.9 59.2 80.6 63.2 64.9 61.9 103.8 81.8 85.2 91.5 76.4 62.3 89.2 70.7 42.7 99.4 70.5 34.7 87.1 64.0 62.2 66.4 7.6 28.6 37.3 24.5 26.3 26.4 30.5 34.8 37.9 34.3 25.3 39.2 29.4 4.3 45.4 27.1 27.1 34.6 19.4 23.7 25.2 25.5 76.6 34.8 27.7 314.6 25.1 49.6 30.5 25.9 26.4 20.9 28.9 22.9 12.1 27.9 31.4 49.3 30.2 22.2 24.2 18.2 19.2 27.2 28.6 25.9 12.9 37.5 86.9 21.2 18.3 37.2 43.6 15.0 24.3 26.1 28.1 14.4 41.3 11.1 41.4 63.2 26.8 16.8 28.5 17.1 25.6 21.8 23.2 37.9 37.0 10.8 22.8 20.3 18.5 17.4 20.0 24.2 17.8 24.9 11.2 31.8 36.8 29.9 7.1 11.5 39.0 15.8 28.2 37.9 46.5 20.7 30.4 23.7 26.7 0.0 28.5 31.7 47.2 24.4 26.6 31.7 162.3 25.2 30.2 24.1 48.9 SRRD "HC/HCC, SRR1L" ENSG00000100104 "SRR1 domain containing" Q9UH36 22 26483877-26494658 "Predicted intracellular proteins" "Biological rhythms, Heme biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 49.0;Late spermatids: 54.9;Pancreatic endocrine cells: 48.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002945 Uncertain Approved Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 1: Pancreatic cells - Digestion" Cytosol "HPA002945: AB_1079265" "unprognostic (3.25e-1)" "unprognostic (3.01e-2)" "unprognostic (1.65e-2)" "unprognostic (1.47e-1)" "unprognostic (1.33e-1)" "unprognostic (2.57e-2)" "prognostic unfavorable (2.16e-6)" "unprognostic (9.00e-2)" "unprognostic (8.51e-3)" "unprognostic (2.49e-2)" "unprognostic (4.50e-3)" "unprognostic (3.93e-2)" "unprognostic (2.63e-1)" "unprognostic (2.70e-1)" "unprognostic (1.03e-1)" "unprognostic (1.76e-3)" "unprognostic (2.96e-1)" 5.0 3.5 8.4 4.1 8.8 6.2 6.2 10.4 9.7 5.5 6.2 6.0 3.6 6.3 6.1 5.3 5.5 3.7 7.6 8.7 8.0 6.4 6.9 5.3 5.6 8.2 8.2 7.1 5.5 6.7 5.1 5.3 7.7 6.8 5.2 5.8 4.9 7.2 19.6 6.0 3.9 7.0 8.1 5.4 4.9 4.8 8.6 5.7 10.5 17.1 7.3 5.5 4.2 8.6 10.7 6.3 10.6 10.9 10.8 6.5 6.1 7.4 10.4 14.7 13.5 6.2 4.6 23.6 5.1 9.7 7.4 9.5 16.6 15.6 14.3 12.2 16.5 10.4 5.5 10.1 7.6 23.1 7.8 6.2 13.4 10.5 16.4 9.7 12.9 13.8 17.2 14.5 9.7 9.2 10.4 7.3 6.6 11.7 7.9 23.3 13.2 17.0 9.7 7.6 11.2 7.6 8.5 7.6 19.7 8.8 9.1 9.0 9.9 11.3 37.2 6.4 13.1 9.5 8.3 19.4 7.7 9.4 15.0 0.3 0.5 0.2 0.7 0.4 1.0 1.1 0.8 1.0 0.5 0.6 1.1 1.2 0.4 0.9 0.4 0.4 0.2 0.3 8.4 8.8 10.4 9.7 8.7 8.0 8.2 8.2 7.7 8.1 8.6 8.6 12.1 0.0 6.4 3.6 10.6 29.7 16.2 7.5 3.4 13.0 10.0 10.5 3.0 12.8 5.9 1.8 2.1 13.3 5.9 3.7 9.8 24.9 22.4 5.8 10.6 11.2 4.8 46.9 3.1 49.0 22.9 8.9 7.7 8.9 11.4 15.1 11.0 15.4 14.1 13.5 3.0 4.5 2.0 3.8 8.6 54.9 7.2 8.6 8.8 1.0 6.1 9.8 10.3 3.5 1.9 48.9 2.4 9.1 10.4 12.1 3.4 19.9 3.2 9.3 6.6 12.6 10.3 17.8 12.9 7.7 31.8 16.7 9.1 21.7 5.9 14.7 SSTR2 ENSG00000180616 "Somatostatin receptor 2" P30874 17 73165010-73176633 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 59.1;Enteroendocrine cells: 35.7;Sertoli cells: 32.9;Smooth muscle cells: 56.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.4" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.4" "Cell line enriched" "Detected in some" 8 "SCLC-21H: 12.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007264 Uncertain Supported Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA007264: AB_1080053" "unprognostic (2.13e-3)" "unprognostic (2.61e-3)" "unprognostic (7.43e-2)" "unprognostic (9.37e-3)" "unprognostic (6.25e-2)" "unprognostic (1.52e-1)" "unprognostic (2.29e-3)" "unprognostic (7.46e-2)" "unprognostic (2.96e-1)" "unprognostic (6.55e-2)" "prognostic favorable (6.63e-4)" "unprognostic (1.07e-1)" "prognostic unfavorable (9.04e-7)" "unprognostic (1.35e-1)" "unprognostic (1.00e-1)" "unprognostic (3.71e-3)" "unprognostic (2.95e-2)" 2.5 3.6 8.4 0.9 8.9 0.9 1.7 7.2 8.7 0.5 0.3 0.8 1.4 0.7 1.6 0.4 1.1 0.6 0.8 9.0 4.3 5.3 1.4 0.4 1.1 2.2 5.1 0.3 0.7 0.3 2.9 0.1 8.6 1.4 1.1 2.2 0.7 1.4 0.7 0.6 0.9 0.8 2.6 6.1 3.1 0.3 4.8 0.5 1.1 0.2 1.3 0.9 0.7 6.8 0.2 0.3 0.3 0.7 0.1 0.1 0.4 0.1 0.2 0.3 0.3 0.2 0.3 0.3 0.2 0.1 0.9 0.3 0.0 0.1 0.1 0.4 0.6 0.3 0.8 0.3 0.0 0.2 1.5 0.1 0.0 0.1 0.0 0.2 0.0 0.4 0.2 0.7 0.0 0.3 0.2 0.8 1.0 0.1 0.4 0.4 0.4 0.3 0.2 0.3 12.5 0.9 0.2 0.2 0.1 0.5 1.5 0.2 0.1 0.2 1.4 0.4 0.2 0.5 0.2 1.0 0.2 0.3 0.2 1.4 0.2 0.3 0.2 0.1 0.2 0.2 0.2 0.2 0.1 0.3 0.2 0.2 1.2 0.2 0.2 0.2 0.1 0.1 8.4 8.9 7.2 8.7 9.0 4.3 2.2 5.1 8.6 2.6 4.8 6.8 4.9 6.4 2.7 1.6 0.5 1.1 3.2 0.0 0.0 59.1 3.7 2.5 3.6 1.5 1.3 1.8 4.2 0.7 0.9 0.1 0.0 0.2 7.0 2.1 1.7 11.3 35.7 0.0 17.1 0.0 0.7 14.3 3.1 4.9 2.5 3.0 3.9 1.0 1.0 6.7 8.4 8.2 0.0 2.4 3.0 5.7 0.9 2.4 5.4 1.9 1.7 2.4 1.0 2.0 0.7 0.4 0.1 0.7 5.8 5.4 0.6 18.0 0.7 4.8 32.9 10.0 56.0 0.9 1.9 0.3 1.1 1.0 1.4 0.6 0.5 3.3 ST13 "FAM10A1, HIP, HSPABP1, P48, SNC6" ENSG00000100380 "ST13 Hsp70 interacting protein" P50502 22 40824535-40856639 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 1091.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043233, HPA046412, HPA047114, HPA047116" Enhanced Enhanced Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA043233: AB_2678377, HPA046412: AB_2679658, HPA047114: AB_2679937, HPA047116: AB_2679939" "unprognostic (1.19e-1)" "unprognostic (2.90e-1)" "unprognostic (1.69e-2)" "unprognostic (7.15e-2)" "unprognostic (2.68e-2)" "prognostic unfavorable (5.23e-4)" "unprognostic (2.73e-3)" "unprognostic (1.74e-2)" "unprognostic (3.63e-1)" "unprognostic (2.50e-1)" "unprognostic (1.00e-1)" "unprognostic (9.54e-2)" "prognostic favorable (3.10e-4)" "unprognostic (8.41e-2)" "unprognostic (3.93e-2)" "unprognostic (3.04e-1)" "unprognostic (8.40e-2)" 163.2 157.5 131.9 84.2 148.3 99.0 161.6 149.9 171.9 163.0 140.4 135.6 96.7 197.5 137.2 116.6 180.6 122.8 121.9 123.8 156.8 254.2 296.7 97.0 111.7 147.3 140.5 542.6 126.2 150.8 92.3 135.3 154.8 145.0 108.0 146.4 111.3 142.6 341.2 98.4 108.3 165.0 147.2 89.0 111.1 107.7 136.1 131.6 176.6 217.9 126.2 131.5 113.5 191.9 249.0 195.1 290.6 255.4 265.7 407.1 263.7 229.0 293.2 279.6 242.3 353.7 144.3 356.8 193.2 232.9 253.7 177.3 387.7 226.3 331.2 228.4 250.3 255.0 379.1 406.4 241.2 374.6 198.5 365.5 235.7 252.6 169.7 351.2 293.6 219.3 313.2 151.2 271.3 187.1 329.5 200.1 166.4 302.0 130.7 375.7 246.4 281.9 284.2 369.8 96.4 97.1 265.0 211.7 337.7 334.1 205.5 233.2 220.8 232.1 223.0 197.0 188.2 173.5 367.9 333.4 317.4 172.0 228.2 108.9 79.5 85.7 84.7 108.7 129.1 146.2 133.0 101.9 107.1 131.6 206.6 160.7 26.3 110.6 146.3 75.5 122.3 162.6 131.9 148.3 149.9 171.9 123.8 156.8 147.3 140.5 154.8 147.2 136.1 191.9 187.0 141.1 220.5 28.1 217.5 311.6 384.6 267.7 279.4 89.5 364.6 359.2 140.1 334.6 232.5 171.0 16.7 382.8 141.7 192.9 563.4 284.8 513.2 431.6 349.8 204.1 262.0 296.3 37.4 205.1 381.2 239.7 107.0 289.6 207.1 305.0 227.7 539.2 328.6 38.7 41.5 263.7 183.1 270.6 374.5 1010.4 510.4 210.3 211.7 15.0 286.7 265.1 157.6 27.2 53.7 193.7 210.8 413.3 129.0 312.2 369.6 1091.8 281.8 73.0 223.5 212.0 268.7 306.9 191.2 193.5 274.5 500.9 200.6 227.3 333.2 325.8 STAB2 "DKFZP434E0321, FEEL-2, FELL, HARE, SCARH1, STAB-2" ENSG00000136011 "Stabilin 2" Q8WWQ8 12 103587273-103766719 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 65.9" "Cell type enriched" "Detected in some" 11 "Hepatic stellate cells: 145.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BEWO: 11.5;HaCaT: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA026871, HPA072699" Enhanced Supported Cytosol NA NA 1200000 "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA026871: AB_1857536, HPA072699: " "unprognostic (5.66e-3)" "unprognostic (7.51e-2)" "unprognostic (3.31e-1)" "unprognostic (3.84e-2)" "unprognostic (8.47e-2)" "unprognostic (2.15e-2)" "unprognostic (1.23e-1)" "unprognostic (2.81e-1)" "unprognostic (5.72e-2)" "unprognostic (1.92e-1)" "unprognostic (4.24e-2)" "unprognostic (1.05e-1)" "unprognostic (9.72e-4)" "unprognostic (1.37e-2)" "unprognostic (5.00e-1)" "unprognostic (1.26e-1)" "unprognostic (2.06e-1)" 0.9 0.2 0.8 0.9 0.5 0.7 0.9 0.1 0.6 1.0 0.0 2.8 0.3 0.9 1.5 0.8 1.3 1.0 0.4 1.3 0.1 0.4 14.7 0.5 3.9 0.4 0.0 0.5 0.3 0.0 0.3 0.3 0.3 0.3 0.4 0.3 0.4 0.0 0.2 0.3 0.6 0.2 0.1 65.9 0.4 2.2 0.3 0.0 1.1 0.0 0.4 0.7 0.5 0.1 0.2 0.5 0.5 0.1 0.0 0.0 11.5 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 3.2 0.0 0.0 0.0 0.0 0.8 0.3 0.7 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.4 0.1 1.8 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.6 0.2 0.0 0.4 0.6 0.3 0.0 0.8 0.1 0.1 0.0 0.2 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.5 0.1 0.6 1.3 0.1 0.4 0.0 0.3 0.1 0.3 0.1 0.2 0.0 0.0 0.7 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.8 4.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 6.1 0.0 0.0 4.0 0.0 0.0 2.7 0.0 0.6 0.2 0.0 0.0 0.0 0.0 145.6 4.1 0.1 0.0 1.9 0.0 0.0 11.6 0.7 12.2 0.3 0.0 0.0 1.0 0.0 0.0 0.0 2.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.0 0.0 0.0 STAC2 24b2 ENSG00000141750 "SH3 and cysteine rich domain 2" Q6ZMT1 17 39210541-39225945 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.5;breast: 56.2;retina: 120.9;skin 1: 53.1" "Cell type enriched" "Detected in many" 9 "Muller glia cells: 496.8" "Cancer enhanced" "Detected in many" "breast cancer: 15.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "GAMG: 9.8;HeLa: 32.5;U-87 MG: 13.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA076925 Approved Cytosol NA NA "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" Cytosol "HPA076925: " "unprognostic (1.70e-3)" "unprognostic (1.05e-1)" "unprognostic (3.09e-2)" "prognostic unfavorable (4.05e-5)" "prognostic unfavorable (5.61e-4)" "unprognostic (1.42e-1)" "unprognostic (8.66e-2)" "unprognostic (2.94e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (1.12e-2)" "unprognostic (5.16e-2)" "unprognostic (2.35e-3)" "unprognostic (2.05e-2)" "unprognostic (1.94e-1)" "unprognostic (3.54e-2)" "unprognostic (3.17e-1)" 2.2 0.5 11.2 0.2 24.6 0.0 56.2 10.3 59.5 8.5 2.2 0.9 0.1 5.2 10.7 0.5 4.8 0.0 2.5 14.5 22.4 14.2 0.0 0.8 0.0 30.9 18.3 2.4 0.2 0.1 1.6 0.2 30.7 5.1 0.1 120.9 15.1 23.5 0.3 53.1 0.6 0.8 5.4 0.1 0.4 0.2 5.4 0.0 0.1 0.6 0.0 0.5 2.6 34.2 0.0 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 9.8 0.0 3.9 0.0 0.0 0.0 0.5 0.0 32.5 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.4 0.3 3.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 24.6 10.3 59.5 14.5 22.4 30.9 18.3 30.7 5.4 5.4 34.2 0.6 3.2 5.8 2.0 0.7 0.4 1.0 0.2 0.0 13.3 52.7 45.3 2.7 0.0 2.5 3.7 10.4 0.1 1.8 0.1 5.9 0.0 0.2 0.3 3.9 1.7 0.0 0.0 19.0 0.0 0.2 1.9 0.0 0.3 0.0 0.2 0.0 0.0 0.1 18.5 16.6 0.0 16.2 0.6 1.5 0.0 2.8 0.8 42.7 3.7 0.0 496.8 2.1 1.0 1.0 0.0 0.0 0.0 0.1 0.5 0.0 0.3 1.5 17.5 0.0 0.2 1.4 0.2 1.0 0.0 1.7 0.3 1.2 0.1 0.1 0.2 STARD10 "CGI-52, NY-CO-28, PCTP2, SDCCAG28" ENSG00000214530 "StAR related lipid transfer domain containing 10" Q9Y365 11 72754729-72794047 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 709.7" "Cell type enhanced" "Detected in all" "Early spermatids: 520.2;Hepatocytes: 660.0;Intestinal goblet cells: 717.9;Late spermatids: 2055.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 21.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 617.7;OE19: 1316.9;SK-BR-3: 427.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026661 Uncertain Supported Cytosol NA NA 13000 "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA026661: AB_1857538" "prognostic favorable (6.92e-4)" "unprognostic (2.07e-1)" "unprognostic (8.03e-2)" "unprognostic (1.74e-3)" "unprognostic (3.71e-2)" "unprognostic (1.37e-2)" "unprognostic (2.50e-2)" "unprognostic (2.16e-1)" "unprognostic (4.16e-1)" "unprognostic (4.69e-2)" "unprognostic (5.81e-2)" "unprognostic (1.67e-1)" "unprognostic (4.24e-3)" "unprognostic (8.42e-2)" "unprognostic (2.29e-1)" "unprognostic (2.12e-2)" "unprognostic (1.04e-1)" 11.8 178.2 35.1 17.7 37.6 10.3 62.1 39.2 41.8 71.9 40.9 180.6 48.5 27.3 102.9 52.0 26.4 59.5 72.5 33.9 34.1 50.1 709.7 37.7 14.5 38.0 33.0 31.0 212.6 73.2 36.2 40.2 38.2 86.2 188.1 18.7 94.5 30.9 66.7 62.6 66.0 26.7 29.9 20.2 266.9 184.3 34.4 15.6 47.9 157.9 21.8 24.5 41.1 35.7 51.2 15.3 7.7 28.7 9.8 9.6 98.3 5.6 26.2 17.3 17.3 209.8 36.7 4.4 16.7 19.2 42.3 31.8 23.4 46.8 20.2 28.3 9.0 5.9 11.1 217.6 35.2 1.6 10.0 6.6 127.0 19.1 26.7 47.2 17.8 10.0 12.1 21.5 3.9 617.7 4.8 11.1 3.4 1316.9 20.1 4.5 13.3 3.4 23.5 61.4 13.0 10.1 8.6 427.4 73.3 32.8 235.5 6.3 13.6 17.0 11.4 6.0 10.1 22.2 19.8 7.5 4.3 5.6 6.5 12.9 2.6 16.0 1.6 1.1 1.2 4.2 1.5 1.7 1.2 2.4 1.6 1.6 21.7 7.5 0.6 2.6 2.1 1.1 35.1 37.6 39.2 41.8 33.9 34.1 38.0 33.0 38.2 29.9 34.4 35.7 10.6 35.3 74.1 8.1 18.1 31.5 76.3 41.0 25.0 10.5 163.3 125.3 45.3 270.2 76.4 55.2 22.9 212.8 17.1 362.8 123.3 70.7 520.2 26.5 6.8 18.5 302.2 22.9 11.6 94.3 93.1 21.1 372.1 25.3 25.4 10.1 30.0 660.0 26.4 33.7 13.9 717.9 85.5 26.0 34.4 2055.8 26.1 12.3 16.0 5.6 7.7 64.4 7.2 8.0 11.8 93.9 398.9 25.2 13.3 150.9 73.5 58.0 34.5 16.6 6.6 11.3 19.6 101.2 22.7 30.2 55.0 352.2 15.6 7.7 440.7 132.7 STAT5B ENSG00000173757 "Signal transducer and activator of transcription 5B" P51692 17 42199177-42276707 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 100.5;Late spermatids: 188.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 121.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004298, CAB005418, HPA042128, HPA049883, HPA051156" Approved Approved Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "CAB004298: AB_2197067, CAB005418: AB_632445, HPA042128: AB_2677864, HPA049883: AB_2680931, HPA051156: AB_2681366" "unprognostic (1.49e-1)" "unprognostic (3.60e-2)" "unprognostic (4.06e-2)" "prognostic favorable (9.37e-4)" "unprognostic (2.68e-1)" "unprognostic (4.29e-1)" "unprognostic (2.23e-1)" "unprognostic (1.03e-1)" "unprognostic (3.06e-2)" "unprognostic (7.98e-2)" "prognostic favorable (1.63e-4)" "unprognostic (1.36e-1)" "prognostic favorable (2.39e-5)" "unprognostic (9.19e-2)" "unprognostic (2.95e-1)" "unprognostic (1.54e-1)" "unprognostic (2.13e-1)" 45.9 45.7 26.4 35.1 26.5 42.4 36.7 33.4 29.0 43.6 24.6 45.3 14.8 59.1 19.3 19.2 50.8 23.6 24.5 23.5 42.9 24.3 24.4 32.5 43.6 32.8 33.9 55.9 22.8 21.1 40.8 31.5 32.9 29.2 17.0 18.7 22.8 34.2 73.3 25.3 30.7 42.7 27.4 42.3 27.6 23.5 49.9 37.6 22.7 46.5 34.7 43.4 31.5 26.1 15.0 22.9 33.3 9.0 40.6 20.4 15.9 15.0 26.5 21.0 18.2 10.1 12.3 48.1 21.8 17.2 41.3 18.7 19.9 13.0 16.6 121.8 23.0 47.1 44.5 15.6 22.3 20.9 72.7 25.1 19.6 15.9 19.9 18.0 33.6 31.9 86.5 10.1 8.8 14.6 99.2 54.9 8.3 34.3 0.2 42.0 20.9 16.8 13.3 23.5 24.5 14.4 27.3 34.4 21.2 7.4 24.3 24.3 26.0 29.2 10.2 15.2 21.2 19.8 9.8 23.9 11.6 21.7 15.5 11.5 3.3 5.9 6.6 3.0 7.1 2.9 9.3 7.6 2.9 2.9 6.5 5.5 22.5 4.2 3.7 2.1 8.4 4.7 26.4 26.5 33.4 29.0 23.5 42.9 32.8 33.9 32.9 27.4 49.9 26.1 30.2 6.4 19.5 41.8 12.9 8.9 5.7 4.5 2.8 21.2 25.1 22.7 20.7 5.7 7.8 3.7 20.9 8.0 31.2 8.4 5.9 8.2 100.5 10.1 22.4 26.0 10.2 12.4 23.7 11.8 6.1 18.8 13.3 15.0 16.4 16.1 20.0 11.2 9.4 10.1 61.2 6.1 8.2 13.3 17.1 188.5 47.2 16.9 10.6 51.5 23.7 9.5 26.8 69.4 60.8 12.2 6.2 74.4 13.6 11.9 7.9 9.8 6.3 13.3 39.5 20.0 23.0 4.3 7.3 5.9 9.8 12.7 34.4 15.5 7.5 7.7 STAU1 "PPP1R150, STAU" ENSG00000124214 "Staufen double-stranded RNA binding protein 1" O95793 20 49113339-49188367 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020839, HPA049892, HPA072004" Approved Enhanced Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB020839: , HPA049892: AB_2680938, HPA072004: " "unprognostic (7.73e-2)" "unprognostic (1.38e-1)" "unprognostic (1.97e-1)" "unprognostic (1.01e-2)" "unprognostic (7.97e-2)" "unprognostic (9.56e-2)" "unprognostic (3.70e-3)" "unprognostic (1.24e-1)" "unprognostic (2.58e-1)" "unprognostic (1.84e-1)" "unprognostic (9.17e-3)" "prognostic unfavorable (4.41e-4)" "unprognostic (1.42e-2)" "unprognostic (2.73e-1)" "unprognostic (8.08e-2)" "unprognostic (1.71e-1)" "unprognostic (1.26e-2)" 46.4 40.4 33.6 34.1 36.5 66.0 40.5 35.5 41.5 41.5 33.7 45.2 54.9 42.3 36.8 47.2 66.3 48.7 49.6 33.5 35.2 88.4 122.8 41.8 36.8 39.3 39.1 36.3 69.7 81.4 15.0 49.9 39.4 46.3 47.1 36.4 39.2 46.1 62.5 41.6 50.9 52.1 37.2 33.3 52.8 35.9 36.5 42.8 69.6 47.1 40.9 51.9 31.1 42.5 113.9 85.1 90.7 40.2 90.1 111.3 100.7 84.4 100.8 246.8 111.2 292.0 121.8 77.1 141.7 106.2 118.3 121.5 122.4 150.8 205.9 30.2 70.5 63.3 62.1 233.0 76.1 51.7 59.9 89.6 126.9 100.5 117.0 100.9 123.0 57.4 112.3 46.7 94.6 72.3 90.7 83.5 74.5 109.1 117.9 69.1 119.4 75.0 100.1 98.2 104.8 93.1 209.9 199.0 124.8 91.6 127.4 72.9 113.0 148.2 128.1 92.6 101.6 41.8 52.3 86.8 108.5 54.6 87.4 31.5 19.3 19.8 17.8 15.8 19.7 16.8 18.9 19.1 16.9 15.4 17.1 16.7 38.0 14.2 20.2 15.9 22.9 13.6 33.6 36.5 35.5 41.5 33.5 35.2 39.3 39.1 39.4 37.2 36.5 42.5 76.5 89.8 82.0 45.7 66.4 112.5 125.5 79.9 95.0 32.9 87.5 65.0 63.1 97.2 71.3 77.3 14.6 105.4 72.2 98.4 93.9 130.6 18.6 146.1 80.1 83.0 76.0 137.4 47.9 118.2 45.0 84.8 71.4 87.3 48.1 79.2 72.8 158.3 64.7 43.7 42.2 77.5 59.0 62.9 91.3 21.9 65.6 66.8 49.8 26.2 85.9 57.0 61.8 39.2 51.2 138.5 89.9 70.0 86.8 189.7 107.8 170.0 105.9 29.1 59.2 72.6 74.2 109.1 69.8 92.1 119.8 194.4 78.5 64.6 69.3 196.5 STIMATE "MGC52022, TMEM110" ENSG00000213533 "STIM activating enhancer" Q86TL2 3 52836219-52897548 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 7.3;Endometrial ciliated cells: 24.2;Extravillous trophoblasts: 6.9;Hofbauer cells: 9.7;Proximal tubular cells: 15.4;Respiratory ciliated cells: 9.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" HPA051855 Uncertain Approved Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 32: U-937 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA051855: AB_2681639" "unprognostic (1.45e-1)" "unprognostic (7.93e-3)" "unprognostic (2.19e-1)" "unprognostic (2.49e-2)" "unprognostic (2.29e-3)" "unprognostic (3.87e-2)" "unprognostic (9.31e-2)" "unprognostic (7.55e-4)" "unprognostic (3.34e-1)" "unprognostic (6.55e-2)" "unprognostic (3.10e-1)" "unprognostic (4.04e-2)" "unprognostic (1.33e-2)" "unprognostic (1.00e-1)" "unprognostic (1.76e-1)" "unprognostic (1.10e-1)" "unprognostic (1.81e-1)" 9.0 9.7 8.1 8.1 7.9 23.2 7.9 7.0 8.0 10.1 4.2 9.1 5.9 10.6 5.6 6.6 12.8 6.9 6.3 6.9 5.9 7.1 30.6 12.1 9.5 8.6 8.0 8.7 11.7 6.0 6.1 5.3 7.5 7.6 4.8 4.6 10.7 7.9 17.5 8.3 8.0 9.4 6.9 11.1 8.6 6.9 7.8 10.3 8.8 5.1 8.2 10.9 7.7 7.8 9.6 8.2 12.6 22.1 27.9 17.7 24.8 13.3 15.5 18.5 17.0 10.2 10.0 9.2 2.6 16.1 17.8 8.7 15.1 13.7 12.8 20.3 10.6 15.3 10.3 15.9 18.4 23.0 11.3 13.8 18.6 20.7 9.3 11.7 15.4 15.2 5.2 9.3 15.8 7.9 12.7 12.9 11.3 8.0 15.8 6.7 8.5 6.4 8.8 12.5 2.7 9.1 14.1 9.5 12.9 6.9 8.2 20.3 15.5 14.8 8.4 19.7 16.5 16.8 11.9 9.0 13.0 23.2 11.5 0.0 1.6 0.9 1.0 3.1 0.9 0.9 1.6 1.2 2.0 0.7 0.8 0.6 0.1 0.4 2.9 1.1 2.4 0.8 8.1 7.9 7.0 8.0 6.9 5.9 8.6 8.0 7.5 6.9 7.8 7.8 2.4 0.0 2.7 0.0 1.3 0.0 0.0 0.0 0.0 0.0 2.6 1.0 0.0 0.0 0.6 7.3 0.0 1.8 1.8 0.0 1.9 2.4 0.0 24.2 1.7 0.5 0.0 0.0 0.0 2.9 6.9 0.8 0.0 1.6 0.0 1.4 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 2.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.7 0.0 0.0 15.4 9.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.9 1.2 4.6 0.0 0.0 STIMATE-MUSTN1 TMEM110-MUSTN1 ENSG00000248592 "STIMATE-MUSTN1 readthrough" 3 52833121-52897562 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "liver: 14.9;skeletal muscle: 9.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 8.8;Karpas-707: 5.8;PC-3: 6.5" HPA051855 Uncertain Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 2: Karpas-707 - Immune response" Cytosol "HPA051855: AB_2681639" "unprognostic (4.19e-2)" "unprognostic (3.85e-2)" "unprognostic (5.95e-2)" "unprognostic (7.28e-2)" "unprognostic (5.35e-2)" "unprognostic (3.11e-4)" "unprognostic (4.73e-2)" "unprognostic (2.66e-2)" "unprognostic (1.59e-2)" "unprognostic (2.51e-2)" "unprognostic (1.57e-2)" "unprognostic (1.84e-2)" "unprognostic (6.01e-6)" "unprognostic (5.49e-2)" "unprognostic (7.31e-2)" "unprognostic (4.55e-2)" "unprognostic (5.09e-5)" 3.6 1.7 0.9 0.5 1.4 1.4 2.6 1.4 2.0 2.9 1.6 1.3 0.0 2.1 0.3 2.1 1.2 0.1 4.4 0.9 0.4 3.1 14.9 2.3 0.1 1.5 1.2 1.6 3.2 0.0 1.4 0.0 1.6 1.4 0.1 0.1 1.6 0.0 9.9 2.0 1.7 0.1 1.9 2.4 2.0 1.4 2.0 0.2 2.1 0.6 0.1 2.5 2.7 2.3 1.8 0.5 0.0 4.0 0.3 0.0 1.1 4.1 0.6 0.1 0.1 0.0 0.5 1.8 0.8 0.0 1.3 1.7 1.0 0.7 0.0 8.8 4.4 2.1 0.0 0.0 0.1 2.8 2.7 0.0 0.2 0.1 0.7 0.0 0.1 2.4 1.6 5.8 0.0 0.6 1.9 0.9 1.4 0.1 6.5 0.8 0.0 1.3 0.0 0.0 0.4 0.7 0.9 0.5 1.9 0.2 0.3 0.9 1.1 0.4 2.2 0.8 2.3 5.0 4.2 0.8 0.9 2.9 1.3 0.0 0.0 0.3 0.0 0.4 0.3 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.9 1.4 1.4 2.0 0.9 0.4 1.5 1.2 1.6 1.9 2.0 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 STK36 "FU, KIAA1278" ENSG00000163482 "Serine/threonine kinase 36" Q9NRP7 2 218672069-218702716 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 37.5;Respiratory ciliated cells: 38.2;Spermatocytes: 28.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027409, HPA027453, HPA030058" Approved Supported Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA027409: AB_10600223, HPA027453: AB_10601893, HPA030058: AB_10601225" "unprognostic (8.11e-2)" "unprognostic (3.77e-1)" "unprognostic (3.59e-2)" "unprognostic (1.27e-1)" "unprognostic (1.50e-1)" "unprognostic (2.52e-2)" "prognostic unfavorable (5.20e-4)" "unprognostic (1.55e-1)" "unprognostic (5.83e-3)" "unprognostic (9.04e-2)" "unprognostic (1.38e-2)" "unprognostic (1.13e-2)" "unprognostic (3.52e-3)" "unprognostic (1.46e-1)" "unprognostic (2.60e-2)" "unprognostic (1.77e-1)" "unprognostic (1.99e-3)" 5.6 9.9 1.5 5.4 1.7 2.5 6.6 1.0 3.2 14.1 15.4 9.0 4.4 11.4 13.4 5.1 14.3 10.5 3.5 2.3 1.0 7.3 4.5 7.3 4.5 1.2 2.6 13.4 10.7 9.4 14.8 4.3 0.8 9.6 6.5 11.6 7.3 8.2 3.7 5.0 6.4 8.0 0.3 5.1 8.8 32.0 1.3 3.2 11.8 2.3 4.0 8.2 7.6 1.0 3.7 8.2 17.6 15.0 18.7 14.5 10.9 9.8 7.8 12.2 11.4 10.7 6.0 4.8 13.3 10.3 8.2 7.2 12.2 10.3 10.7 2.8 10.2 4.7 27.1 15.0 9.1 6.7 7.6 15.7 7.5 12.0 8.4 32.3 9.3 6.2 11.1 6.0 10.3 8.5 4.0 8.5 10.7 4.6 5.2 7.3 7.6 5.1 14.9 18.2 14.2 12.3 7.6 12.2 5.0 18.2 12.4 5.3 8.9 16.8 6.1 6.5 6.8 7.5 6.3 2.5 10.4 3.1 7.1 0.0 0.4 0.7 0.3 0.2 0.1 0.4 0.2 0.2 0.3 0.1 0.2 0.3 0.0 0.5 0.3 0.3 0.2 0.4 1.5 1.7 1.0 3.2 2.3 1.0 1.2 2.6 0.8 0.3 1.3 1.0 2.1 9.6 6.3 18.3 1.6 1.1 0.9 3.6 2.8 7.4 7.4 5.5 4.0 5.7 3.7 3.7 37.5 1.8 2.9 2.9 0.0 3.7 16.9 17.5 9.0 3.3 2.4 0.8 22.0 2.5 1.5 4.5 10.7 6.3 1.3 12.2 3.3 5.9 2.7 1.7 18.0 4.4 6.1 2.5 1.2 6.0 5.9 2.0 0.0 2.8 2.5 4.9 1.0 8.5 6.2 2.2 5.0 4.9 0.6 1.6 2.5 4.4 38.2 9.1 6.6 3.1 4.0 28.0 8.9 3.7 1.0 0.8 1.5 11.0 4.9 0.9 STK38 "NDR, NDR1" ENSG00000112079 "Serine/threonine kinase 38" Q15208 6 36493892-36547479 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 101.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004673, HPA038623, HPA051324" Uncertain Approved Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "CAB004673: AB_425892, HPA038623: AB_10967059, HPA051324: AB_2681442" "unprognostic (3.58e-3)" "unprognostic (1.80e-2)" "unprognostic (3.07e-2)" "unprognostic (6.76e-3)" "unprognostic (8.25e-2)" "unprognostic (1.47e-2)" "unprognostic (2.88e-3)" "unprognostic (2.08e-1)" "prognostic unfavorable (9.44e-5)" "unprognostic (3.78e-2)" "unprognostic (2.18e-1)" "unprognostic (3.21e-2)" "unprognostic (1.98e-2)" "unprognostic (3.80e-1)" "unprognostic (2.59e-1)" "unprognostic (1.69e-1)" "unprognostic (3.13e-3)" 27.6 11.5 13.2 28.9 13.6 30.6 23.2 15.8 18.1 23.5 15.2 40.4 24.0 21.3 12.5 39.6 21.4 20.7 24.2 14.2 13.4 23.1 24.7 24.9 34.5 14.4 13.4 16.0 12.5 8.3 14.4 21.7 13.6 23.8 36.5 11.3 33.6 16.0 16.1 30.6 41.6 27.4 13.0 34.6 23.2 13.8 14.8 28.0 14.0 16.2 33.8 30.0 28.4 14.2 43.0 31.1 32.1 34.8 63.4 47.9 27.9 46.7 37.6 47.6 47.4 24.0 28.7 57.3 35.3 70.0 39.5 44.7 26.9 19.6 55.7 23.6 23.0 41.1 40.8 21.9 31.2 15.8 21.7 31.9 50.0 36.9 23.6 54.5 30.1 28.7 34.0 32.4 68.5 25.7 25.5 40.8 13.4 50.5 27.3 97.7 38.9 15.3 45.0 52.9 37.4 17.7 57.0 25.9 34.0 35.7 27.8 40.8 29.4 38.4 33.6 30.9 30.7 27.1 51.4 39.9 8.7 60.1 37.8 91.2 45.2 34.6 57.0 49.5 44.1 22.4 46.9 50.4 29.1 16.2 41.1 45.8 59.4 59.3 73.3 14.4 48.7 58.3 13.2 13.6 15.8 18.1 14.2 13.4 14.4 13.4 13.6 13.0 14.8 14.2 29.7 19.2 16.0 27.4 25.7 13.5 9.6 21.5 21.1 3.0 16.0 14.5 15.5 18.6 47.9 7.3 0.0 13.8 59.5 47.1 1.9 18.9 9.0 15.3 16.0 18.4 14.4 16.6 46.5 12.7 17.8 22.2 34.7 20.4 13.3 13.5 12.1 15.0 13.2 5.0 34.2 25.4 22.4 38.2 20.3 5.3 27.1 40.1 17.8 57.1 48.7 7.6 101.0 38.2 36.8 27.8 30.8 30.1 39.6 12.8 32.8 16.6 40.4 7.7 13.1 8.3 14.0 26.5 10.3 31.5 21.2 15.3 45.5 10.1 28.4 27.9 STK38L "KIAA0965, NDR2" ENSG00000211455 "Serine/threonine kinase 38 like" Q9Y2H1 12 27243968-27325959 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Actin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 49.9;granulocytes: 80.7;monocytes: 33.0" "Cell line enhanced" "Detected in all" "HDLM-2: 157.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038623, HPA051324" Approved Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 1: Pancreatic cells - Digestion" Cytosol "HPA038623: AB_10967059, HPA051324: AB_2681442" "unprognostic (2.14e-2)" "unprognostic (1.01e-1)" "unprognostic (9.94e-2)" "unprognostic (2.43e-2)" "unprognostic (2.02e-1)" "unprognostic (1.76e-1)" "unprognostic (3.33e-2)" "unprognostic (4.68e-2)" "unprognostic (5.56e-2)" "unprognostic (1.56e-1)" "prognostic unfavorable (5.82e-4)" "unprognostic (1.16e-1)" "unprognostic (3.41e-2)" "unprognostic (1.09e-1)" "unprognostic (1.95e-1)" "unprognostic (5.05e-2)" "unprognostic (1.05e-2)" 23.9 11.6 6.5 21.6 8.6 17.2 14.0 6.9 11.1 17.2 6.4 28.9 12.9 27.1 7.5 22.7 15.1 25.7 44.9 6.7 8.6 12.9 12.5 12.3 12.4 8.1 7.5 7.0 12.3 26.9 7.2 15.7 8.4 20.2 21.2 6.6 13.8 15.0 8.8 10.8 14.3 33.3 7.6 12.0 18.6 11.2 9.5 17.8 9.2 16.4 14.8 24.6 15.5 6.8 12.0 15.7 40.1 17.7 18.6 12.4 30.8 7.7 11.5 4.8 6.5 19.8 8.5 29.3 17.7 6.4 13.6 21.9 19.0 13.4 7.2 157.8 17.3 18.7 17.5 10.0 15.5 43.7 19.7 14.7 13.3 17.6 21.7 29.3 38.1 36.8 21.2 21.1 9.7 8.3 28.5 46.3 49.6 31.2 25.4 10.6 47.8 22.4 6.8 22.0 6.7 22.3 33.1 19.9 13.3 38.6 9.8 14.0 16.4 15.5 13.9 23.7 20.3 7.7 8.1 29.1 8.0 19.9 6.7 16.3 33.0 60.8 10.0 28.4 7.0 11.6 7.7 9.8 49.9 9.3 9.4 7.6 80.7 11.6 22.4 21.2 10.8 14.7 6.5 8.6 6.9 11.1 6.7 8.6 8.1 7.5 8.4 7.6 9.5 6.8 24.4 19.2 16.2 32.7 20.8 35.4 36.3 88.2 22.2 12.7 16.2 14.7 76.0 10.0 33.7 9.2 2.1 11.0 21.7 33.6 9.8 49.8 23.1 12.5 15.3 26.2 19.2 15.4 57.2 40.1 9.1 19.7 15.3 14.9 17.7 10.9 24.3 14.5 28.8 10.1 37.5 33.8 18.3 36.4 73.7 5.9 6.5 45.7 21.4 37.5 46.2 8.1 14.4 42.3 16.0 70.5 26.3 12.0 22.8 24.8 9.2 16.2 11.9 7.9 19.7 8.6 41.1 12.1 13.4 20.5 32.0 27.8 15.7 9.7 23.0 42.0 STMN1 "C1orf215, FLJ32206, Lag, LAP18, OP18, PP17, PP19, PR22, SMN" ENSG00000117632 "Stathmin 1" P16949 1 25884181-25906991 "Cancer-related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 951.6;lymphoid tissue: 1343.2" "Cell type enhanced" "Detected in all" "Late spermatids: 2537.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 424.6" "Group enriched" "Detected in all" 5 "dendritic cells: 424.6;T-cells: 143.3" "Cell line enhanced" "Detected in all" "MOLT-4: 3270.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010107, HPA068438" Enhanced Approved Cytosol NA NA 320000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "CAB010107: AB_628297, HPA068438: " "unprognostic (6.30e-2)" "unprognostic (2.40e-3)" "unprognostic (5.31e-2)" "unprognostic (7.94e-2)" "unprognostic (1.89e-1)" "unprognostic (5.02e-2)" "prognostic unfavorable (9.90e-7)" "unprognostic (9.45e-2)" "unprognostic (1.39e-2)" "unprognostic (1.61e-2)" "unprognostic (1.78e-1)" "unprognostic (3.33e-3)" "unprognostic (1.02e-2)" "unprognostic (1.68e-1)" "unprognostic (4.46e-2)" "unprognostic (1.05e-1)" "unprognostic (3.00e-2)" 56.4 69.1 526.8 103.8 568.0 260.5 60.6 514.2 951.6 57.7 333.6 93.2 70.5 129.8 40.7 115.9 45.2 51.1 56.0 573.2 568.2 77.7 35.8 60.7 253.2 560.1 516.8 172.4 23.2 43.8 103.5 120.1 552.4 31.7 110.6 304.7 43.4 32.7 29.5 56.3 89.1 100.0 537.1 72.8 54.5 387.0 531.7 1343.2 33.6 29.9 246.0 58.9 76.0 791.9 1026.8 226.1 2191.0 882.5 128.9 126.0 225.7 776.3 609.7 1081.9 1037.9 157.2 1018.3 1260.3 426.3 572.0 425.8 304.6 618.6 450.9 1616.1 390.4 310.9 786.0 363.3 547.6 51.9 994.6 529.3 77.0 65.6 439.6 496.8 405.5 833.6 1594.4 1074.4 1203.0 1429.6 268.0 3270.7 1441.5 1350.8 615.1 302.8 1907.9 1709.2 740.7 536.9 91.7 1479.2 1282.3 710.0 348.3 638.4 695.8 500.7 1240.1 406.2 721.8 853.6 634.3 664.8 702.5 1212.0 1535.8 357.7 1904.8 798.2 13.4 4.1 23.5 53.9 8.6 32.2 37.0 47.8 68.2 23.2 45.6 77.8 71.6 1.9 56.3 4.5 424.6 143.3 57.2 526.8 568.0 514.2 951.6 573.2 568.2 560.1 516.8 552.4 537.1 531.7 791.9 257.3 41.7 31.6 32.7 125.1 201.6 148.9 350.0 577.7 454.6 91.0 175.1 77.2 31.5 100.0 174.7 64.6 439.3 261.7 35.1 226.9 148.9 917.2 92.8 100.3 196.3 250.8 505.7 109.5 20.1 604.1 134.9 121.3 141.1 262.0 712.4 109.2 15.4 530.1 195.2 73.0 100.9 567.6 87.3 287.0 2537.2 44.7 130.0 268.6 32.8 32.1 252.4 84.5 38.2 217.4 59.0 69.3 47.0 261.7 63.5 21.0 221.4 59.1 183.6 39.5 68.0 267.6 873.0 260.8 423.9 90.4 130.4 224.9 66.5 177.1 95.7 STOML1 "FLJ36370, hUNC-24, SLP-1, STORP" ENSG00000067221 "Stomatin like 1" Q9UBI4 15 73978926-73994622 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042353 Approved Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 65: Brain - Ion transport" "Cluster 18: U-2197 - ECM organization" "Cluster 1: Pancreatic cells - Digestion" Cytosol "HPA042353: AB_10797387" "unprognostic (5.75e-2)" "unprognostic (1.70e-1)" "unprognostic (7.76e-2)" "unprognostic (4.54e-3)" "unprognostic (1.39e-2)" "unprognostic (1.81e-2)" "unprognostic (1.54e-1)" "unprognostic (2.45e-1)" "unprognostic (1.78e-1)" "unprognostic (2.64e-1)" "unprognostic (1.13e-1)" "unprognostic (2.30e-3)" "unprognostic (2.26e-3)" "unprognostic (2.14e-1)" "unprognostic (1.37e-1)" "unprognostic (1.55e-1)" "unprognostic (2.67e-2)" 11.4 17.3 33.0 6.5 33.7 4.5 10.4 22.0 38.5 9.8 17.1 11.0 5.9 9.1 5.6 9.4 7.3 6.3 23.6 36.8 32.4 8.6 13.2 10.2 5.6 34.6 30.5 8.5 10.1 7.8 16.6 7.5 36.8 9.9 3.6 3.1 8.3 8.8 18.6 9.4 7.9 7.7 26.5 7.9 9.5 13.1 32.6 8.1 13.6 8.9 3.8 11.8 9.2 28.4 5.8 10.8 6.4 8.8 12.7 8.0 5.4 18.3 7.1 9.8 8.3 3.2 31.4 5.8 28.3 14.9 7.3 18.9 6.1 12.9 3.1 19.4 6.6 6.1 10.0 3.6 12.5 4.0 4.6 14.3 9.9 15.4 14.5 8.1 9.3 13.1 14.6 10.9 14.3 8.8 7.6 2.9 3.1 8.9 8.6 4.5 6.5 8.9 20.7 6.3 12.1 7.9 8.4 10.9 11.9 4.0 9.1 4.4 14.3 22.4 7.2 25.8 24.9 10.6 5.8 3.0 20.6 12.1 11.6 1.0 4.1 2.5 5.3 7.7 4.4 4.5 4.3 7.0 6.5 5.6 8.7 9.2 2.1 8.0 18.2 11.5 8.1 5.5 33.0 33.7 22.0 38.5 36.8 32.4 34.6 30.5 36.8 26.5 32.6 28.4 15.2 0.0 4.1 7.2 5.3 3.2 3.7 7.2 1.8 13.1 7.0 4.8 10.8 2.8 5.8 7.3 6.2 13.0 3.5 8.9 1.9 25.1 1.0 2.8 6.2 7.7 10.2 4.2 6.9 19.0 8.6 11.4 12.8 5.4 4.5 8.5 5.0 5.1 10.8 16.8 8.1 7.3 4.1 3.3 2.2 2.6 9.0 3.3 3.6 2.8 2.5 11.9 2.1 7.5 4.1 20.8 4.9 11.7 3.4 6.8 12.6 4.8 2.7 14.0 6.6 7.5 9.7 20.8 7.8 4.7 2.0 5.6 4.1 13.7 5.6 3.3 STRA8 ENSG00000146857 "Stimulated by retinoic acid 8" Q7Z7C7 7 135231979-135258492 "Predicted intracellular proteins" "Differentiation, DNA replication, Meiosis, Oogenesis, Spermatogenesis, Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "choroid plexus: 6.6" "Cell type enriched" "Detected in some" 6 "Spermatogonia: 10.8" "Cancer enhanced" "Detected in many" "renal cancer: 2.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.5;THP-1: 2.4;U-266/84: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA078044 Approved Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Cytosol "HPA078044: " "unprognostic (2.84e-1)" "unprognostic (4.86e-2)" "unprognostic (3.89e-2)" "unprognostic (9.67e-4)" "unprognostic (1.21e-1)" "unprognostic (1.01e-1)" "unprognostic (1.02e-1)" "unprognostic (1.26e-3)" "unprognostic (1.25e-1)" "unprognostic (8.55e-3)" "unprognostic (1.45e-1)" "unprognostic (2.69e-1)" 0.1 0.0 0.6 0.0 0.5 0.0 0.0 0.3 0.5 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.3 0.3 0.0 0.1 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 0.0 0.3 0.0 0.0 0.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.1 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 2.4 0.1 0.1 0.0 0.0 0.0 0.2 1.5 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.3 0.5 1.0 0.3 0.6 0.5 0.6 0.3 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.8 10.8 0.0 0.0 0.8 0.0 0.0 0.0 0.0 STRAP "MAWD, pt-wd, UNRIP" ENSG00000023734 "Serine/threonine kinase receptor associated protein" Q9Y3F4 12 15882387-15903478 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027320, HPA055557, HPA073876" Approved Enhanced Cytosol NA NA 200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA027320: AB_1857614, HPA055557: AB_2682849, HPA073876: AB_2686639" "unprognostic (4.64e-3)" "unprognostic (2.25e-2)" "unprognostic (9.88e-2)" "unprognostic (1.42e-2)" "unprognostic (2.88e-1)" "unprognostic (4.05e-3)" "prognostic unfavorable (6.83e-6)" "unprognostic (1.69e-2)" "unprognostic (3.71e-1)" "unprognostic (2.15e-2)" "unprognostic (1.53e-1)" "unprognostic (1.02e-1)" "unprognostic (3.60e-3)" "unprognostic (5.93e-2)" "unprognostic (2.54e-1)" "prognostic unfavorable (9.07e-4)" "prognostic unfavorable (5.10e-4)" 70.4 70.2 48.1 54.7 52.5 51.8 49.8 44.4 63.7 51.8 41.4 55.5 46.2 52.2 50.5 60.9 44.4 46.9 93.1 54.8 65.3 84.9 80.3 46.8 54.9 49.9 54.5 40.3 72.0 83.9 58.4 64.6 61.6 49.3 52.8 85.5 48.8 48.7 135.9 44.1 44.9 68.8 47.6 40.3 48.5 50.3 59.0 66.5 77.7 114.6 57.2 70.4 41.3 50.9 195.6 226.2 209.7 179.8 182.3 180.6 280.5 227.9 158.2 200.8 186.4 325.9 167.2 215.6 110.6 233.5 199.3 138.0 254.6 251.0 293.2 291.3 206.1 218.6 163.8 144.7 298.8 258.2 102.0 176.9 209.7 224.6 248.6 221.6 237.9 139.6 170.9 63.9 264.3 137.3 215.6 122.6 743.6 124.8 145.8 162.4 289.7 124.5 232.5 197.8 134.8 228.8 184.7 125.5 258.7 415.8 235.5 135.9 201.3 149.0 177.0 160.3 284.7 73.0 106.1 351.5 183.7 140.1 193.9 74.2 73.9 65.8 66.3 87.4 75.1 76.1 67.8 64.2 92.5 66.7 65.8 70.0 33.7 64.3 80.5 56.8 92.2 84.5 48.1 52.5 44.4 63.7 54.8 65.3 49.9 54.5 61.6 47.6 59.0 50.9 111.7 38.5 45.2 19.9 111.2 243.4 177.6 131.5 116.7 90.1 87.8 65.9 104.0 51.5 84.8 66.2 35.5 154.3 121.2 41.5 275.9 171.1 44.3 63.2 82.1 100.3 106.2 103.7 42.8 137.2 201.2 109.7 61.7 78.6 46.3 112.1 71.7 82.1 108.8 60.6 43.4 59.7 128.1 86.2 143.8 86.2 69.9 89.4 128.1 22.5 99.2 207.9 93.7 24.1 33.9 144.2 66.1 102.0 119.5 218.3 56.0 228.5 58.9 100.9 78.9 96.4 139.0 168.1 80.4 115.6 227.9 295.1 111.3 135.2 95.6 192.5 STRIP1 "FAM40A, FAR11A, FLJ14743, KIAA1761" ENSG00000143093 "Striatin interacting protein 1" Q5VSL9 1 110031577-110074641 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 58.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060302, HPA060498" Approved Supported Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA060302: AB_2684247, HPA060498: AB_2684293" "unprognostic (2.75e-2)" "unprognostic (3.91e-1)" "unprognostic (2.81e-2)" "unprognostic (1.63e-1)" "unprognostic (5.09e-1)" "unprognostic (2.90e-2)" "unprognostic (1.01e-2)" "unprognostic (9.08e-2)" "unprognostic (2.83e-1)" "unprognostic (6.29e-2)" "unprognostic (1.41e-3)" "unprognostic (2.86e-1)" "unprognostic (1.42e-1)" "unprognostic (1.88e-2)" "unprognostic (1.82e-1)" "unprognostic (6.23e-2)" "unprognostic (2.23e-2)" 14.9 14.9 13.0 11.7 13.9 22.6 13.9 9.9 14.3 19.2 8.8 16.1 13.1 19.1 15.6 15.2 15.6 10.8 12.7 14.5 13.4 12.3 9.8 12.7 15.6 11.9 12.9 21.5 12.6 21.3 15.7 16.6 14.0 12.9 13.4 11.9 14.1 13.8 14.1 17.5 19.7 18.0 10.1 22.6 13.5 19.4 17.2 16.2 13.6 13.7 15.4 15.4 14.9 12.0 19.7 12.8 34.3 23.4 29.3 19.3 24.7 30.3 26.3 30.9 26.8 13.5 11.2 16.0 16.2 27.0 19.6 18.3 18.4 21.5 21.7 34.2 22.3 26.7 23.1 17.7 16.2 24.3 25.6 20.7 25.3 26.2 28.6 22.7 25.0 21.6 24.1 19.9 30.3 23.3 28.0 25.5 27.9 14.8 17.2 27.0 44.1 14.3 21.4 28.5 44.1 25.4 25.9 32.4 19.5 19.7 16.2 21.9 25.9 23.2 22.1 27.2 20.5 20.3 12.0 16.3 26.5 25.9 34.2 13.9 10.5 14.8 14.9 11.4 13.0 10.7 12.5 15.7 12.2 10.2 14.4 13.0 9.6 16.1 15.5 5.6 12.6 12.8 13.0 13.9 9.9 14.3 14.5 13.4 11.9 12.9 14.0 10.1 17.2 12.0 9.0 3.2 7.8 17.3 16.4 13.8 10.0 7.2 9.6 12.6 8.3 5.7 8.5 4.3 8.2 9.2 18.8 16.1 11.9 15.5 1.9 10.7 47.3 9.1 9.6 13.2 15.0 13.0 15.6 7.2 10.4 10.6 11.7 15.1 7.0 16.2 14.6 9.8 12.9 6.7 17.7 13.0 8.2 11.1 11.6 58.0 9.9 8.9 3.6 7.5 14.3 7.1 17.5 15.1 12.6 12.5 10.2 10.1 11.9 11.5 23.1 3.9 3.0 18.9 6.6 11.4 12.5 11.3 10.2 10.9 12.8 25.9 15.2 13.0 11.5 14.1 STRIP2 "FAM40B, FAR11B, KIAA1170" ENSG00000128578 "Striatin interacting protein 2" Q9ULQ0 7 129434432-129488399 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.0;choroid plexus: 80.0;skeletal muscle: 28.6" "Cell type enhanced" "Detected in many" "Astrocytes: 54.9;Cardiomyocytes: 49.5;Muller glia cells: 62.1;Oligodendrocyte precursor cells: 29.7;Spermatocytes: 79.1;Spermatogonia: 37.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 4 "basal ganglia: 41.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-2197: 44.7" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 102.5" HPA019657 Approved Approved Cytosol NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol "HPA019657: AB_1848399" "unprognostic (1.95e-1)" "unprognostic (2.45e-1)" "unprognostic (2.11e-1)" "unprognostic (2.41e-1)" "unprognostic (4.32e-1)" "unprognostic (1.43e-2)" "unprognostic (2.80e-3)" "prognostic unfavorable (6.78e-4)" "unprognostic (9.05e-2)" "unprognostic (2.25e-1)" "unprognostic (8.99e-2)" "unprognostic (1.95e-1)" "unprognostic (2.87e-6)" "prognostic favorable (5.41e-4)" "unprognostic (4.06e-2)" "unprognostic (5.34e-2)" "unprognostic (7.50e-2)" 0.4 2.3 3.7 1.6 41.0 3.6 0.4 3.9 10.2 0.3 80.0 0.6 0.5 0.4 0.3 1.1 0.2 0.8 9.5 4.4 1.8 4.7 0.5 1.0 2.4 0.8 8.0 0.7 0.9 0.1 8.2 0.9 1.0 1.1 0.9 22.1 1.3 0.1 28.6 0.9 0.9 0.5 2.8 1.2 0.7 14.2 8.9 1.3 0.4 19.4 1.7 0.7 0.4 2.4 15.4 6.5 5.9 9.3 2.3 2.0 25.5 6.1 7.7 10.2 9.8 3.6 8.5 6.4 0.8 2.6 33.2 16.9 6.4 5.5 15.4 37.6 5.3 4.9 11.5 3.7 1.5 3.1 25.0 2.4 1.9 17.3 10.6 16.8 17.8 5.7 21.7 3.8 39.7 0.8 8.2 7.8 5.7 3.3 13.4 5.4 10.9 1.2 3.7 5.7 1.3 1.3 14.2 1.0 3.1 4.4 1.8 7.6 6.4 5.9 5.8 44.7 18.0 3.6 2.5 7.6 39.4 7.9 8.5 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 3.7 41.0 3.9 10.2 4.4 1.8 0.8 8.0 1.0 2.8 8.9 2.4 0.4 3.2 1.1 54.9 0.8 0.3 0.3 0.3 0.0 10.5 0.5 0.4 49.5 0.0 0.3 0.0 2.1 0.7 0.8 2.1 0.0 0.9 5.7 0.2 0.9 1.1 0.0 9.1 18.6 3.8 3.8 3.2 2.0 0.4 7.6 1.0 0.4 0.2 0.8 1.7 16.7 1.0 0.0 0.3 0.3 9.9 0.6 2.1 1.8 7.5 7.8 62.1 0.0 29.7 1.0 5.0 4.4 0.7 1.4 0.6 0.1 13.7 0.8 3.5 0.0 2.3 0.9 79.1 37.1 0.5 0.1 0.3 1.3 0.5 0.8 0.6 STRN4 "PPP2R6C, ZIN" ENSG00000090372 "Striatin 4" Q9NRL3 19 46719511-46746994 "Predicted intracellular proteins, Predicted membrane proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043051, HPA043527, HPA056706" Supported Approved Cytosol NA NA 32000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA043051: AB_2678290, HPA043527: AB_10959664, HPA056706: AB_2683214" "unprognostic (3.57e-2)" "unprognostic (7.96e-2)" "unprognostic (2.13e-2)" "unprognostic (7.39e-2)" "unprognostic (1.81e-1)" "unprognostic (1.96e-2)" "prognostic unfavorable (6.06e-8)" "unprognostic (8.31e-3)" "unprognostic (5.34e-2)" "prognostic unfavorable (2.98e-4)" "unprognostic (1.56e-1)" "unprognostic (9.41e-3)" "unprognostic (4.86e-3)" "unprognostic (6.74e-2)" "unprognostic (4.06e-2)" "unprognostic (6.04e-2)" "unprognostic (1.84e-1)" 34.2 25.3 25.5 19.5 25.3 37.6 32.8 15.5 31.1 33.5 19.7 38.0 22.6 37.0 7.9 48.1 32.8 19.6 37.1 32.5 21.4 29.2 23.0 33.8 21.2 19.1 18.8 30.9 36.5 21.3 22.8 20.4 17.6 33.2 12.8 9.7 31.0 19.8 36.1 42.5 30.5 17.7 17.8 42.8 33.8 85.3 24.9 19.4 27.7 15.5 11.6 35.2 34.2 23.5 60.8 79.2 67.5 50.2 19.1 21.1 47.7 51.2 27.4 52.0 45.3 59.7 52.5 30.1 30.2 42.0 42.5 42.2 31.9 49.8 20.3 43.7 66.9 66.3 52.4 51.4 60.8 54.1 69.5 33.8 49.1 33.5 45.5 26.2 46.8 34.9 59.2 38.2 22.1 41.4 60.6 143.4 51.8 63.5 37.1 55.1 41.2 23.3 34.9 107.0 83.5 89.8 71.7 66.1 34.5 29.0 49.7 60.5 64.3 38.8 58.4 26.9 76.4 48.5 74.1 45.0 33.9 33.8 81.9 4.2 6.0 2.8 1.0 9.1 0.3 1.4 0.8 0.7 3.1 2.5 0.4 0.9 9.3 1.4 5.7 2.7 0.3 5.8 25.5 25.3 15.5 31.1 32.5 21.4 19.1 18.8 17.6 17.8 24.9 23.5 28.4 3.2 7.5 6.2 7.7 17.2 10.7 11.6 6.2 14.7 17.7 15.0 12.1 14.3 8.9 7.3 12.5 14.6 10.4 28.3 1.9 12.6 11.4 15.7 17.9 23.9 17.5 11.6 13.7 15.4 18.1 11.4 15.3 18.2 0.0 22.5 20.3 12.3 14.8 30.3 11.1 23.0 10.2 24.1 14.6 19.6 17.7 22.9 10.6 13.1 16.9 7.9 2.1 5.5 12.1 19.8 17.7 19.9 8.0 18.3 15.4 7.4 9.0 7.9 6.6 13.4 14.3 19.8 44.9 16.8 17.3 20.0 8.5 18.6 18.9 17.8 STUM "C1orf95, DKFZp761P211" ENSG00000203685 "Stum, mechanosensory transduction mediator homolog" Q69YW2 1 226548764-226609230 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "brain: 234.8" "Cell type enhanced" "Detected in some" "Distal tubular cells: 9.8;Endometrial stromal cells: 3.8;Fibroblasts: 1.5;Glandular and luminal cells: 1.6;Smooth muscle cells: 2.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "medulla oblongata: 234.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HEL: 29.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "amygdala: 70.3;basal ganglia: 76.6;cerebral cortex: 75.5;hippocampal formation: 74.0;thalamus: 21.3" HPA074381 Approved Cytosol NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 36: HEL - Hemostasis" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA074381: AB_2732253" "unprognostic (3.23e-3)" "unprognostic (1.42e-1)" "unprognostic (1.58e-1)" "unprognostic (1.94e-1)" "unprognostic (4.09e-2)" "unprognostic (2.68e-2)" "unprognostic (2.64e-2)" "unprognostic (1.41e-3)" "unprognostic (3.07e-1)" "unprognostic (5.15e-2)" "unprognostic (7.62e-2)" "unprognostic (3.28e-2)" "prognostic favorable (6.40e-4)" "unprognostic (1.14e-2)" "unprognostic (9.04e-2)" "unprognostic (5.89e-2)" "unprognostic (1.79e-3)" 3.7 1.0 45.5 1.2 40.0 0.0 2.8 0.0 43.7 3.1 0.0 15.7 1.6 3.2 1.3 5.7 3.1 0.8 2.2 38.8 17.6 5.5 0.1 0.5 0.2 234.8 30.0 2.5 0.9 0.9 7.4 0.4 101.9 4.0 2.1 1.4 1.0 1.2 3.6 4.2 2.7 5.8 9.4 1.0 2.3 1.4 49.5 0.5 0.7 1.3 0.3 6.8 3.5 5.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 4.9 0.4 29.9 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.4 0.3 0.0 4.4 0.0 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.5 40.0 0.0 43.7 38.8 17.6 234.8 30.0 101.9 9.4 49.5 5.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.8 0.0 0.0 1.0 3.8 0.2 0.0 0.0 0.0 0.2 0.5 1.5 0.0 1.6 0.0 0.8 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 STXBP2 "Hunc18b, UNC18B" ENSG00000076944 "Syntaxin binding protein 2" Q15833 19 7636881-7647873 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 194.2" "Cell type enhanced" "Detected in many" "Kupffer cells: 262.5;Macrophages: 249.1;monocytes: 368.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 248.6;classical monocyte: 471.0;eosinophil: 295.6;intermediate monocyte: 604.8;myeloid DC: 239.7;neutrophil: 356.2;non-classical monocyte: 893.3" "Group enriched" "Detected in all" 6 "dendritic cells: 239.7;granulocytes: 356.2;monocytes: 893.3" "Cell line enhanced" "Detected in many" "HMC-1: 244.8;U-937: 224.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015564, HPA063868" Approved Enhanced Cytosol No No 870000 "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "HPA015564: AB_1857626, HPA063868: AB_2685136" "unprognostic (1.20e-2)" "unprognostic (6.17e-3)" "unprognostic (2.85e-2)" "prognostic favorable (2.29e-4)" "unprognostic (2.54e-1)" "unprognostic (1.75e-3)" "prognostic unfavorable (4.65e-4)" "unprognostic (4.22e-3)" "unprognostic (2.35e-1)" "unprognostic (6.25e-2)" "unprognostic (1.79e-1)" "unprognostic (4.99e-2)" "unprognostic (1.51e-1)" "unprognostic (4.62e-2)" "unprognostic (2.85e-1)" "prognostic favorable (7.68e-4)" "prognostic favorable (5.13e-6)" 24.2 22.8 5.2 65.9 6.3 194.2 24.3 4.8 10.9 22.2 9.3 52.5 67.4 8.4 33.2 73.1 27.7 28.4 7.5 5.1 6.2 62.4 49.0 89.6 51.0 8.3 6.6 5.3 86.7 36.1 29.4 36.3 7.9 52.1 37.0 4.2 79.4 22.8 2.9 52.3 63.9 14.6 6.7 162.2 71.9 74.9 8.8 85.3 52.0 3.0 34.6 34.6 34.8 9.3 113.0 39.1 0.9 0.5 0.0 0.9 75.6 14.2 1.5 2.7 7.4 92.5 69.6 29.6 55.4 11.3 49.5 75.5 4.1 67.5 2.7 124.1 46.9 127.8 49.7 55.8 63.6 83.2 244.8 4.4 67.4 13.4 38.0 0.3 58.5 74.7 81.4 98.5 0.0 70.9 41.2 193.2 28.7 72.7 68.0 41.8 0.3 114.7 55.0 128.1 11.5 0.6 34.0 49.6 2.2 35.6 61.9 212.7 61.7 0.4 21.8 1.5 0.8 108.4 58.6 38.8 1.2 224.8 2.7 248.6 471.0 295.6 69.9 604.8 56.7 47.3 52.7 63.8 239.7 52.2 36.6 44.3 356.2 74.7 893.3 91.5 78.9 306.9 5.2 6.3 4.8 10.9 5.1 6.2 8.3 6.6 7.9 6.7 8.8 9.3 2.1 0.0 7.7 0.7 44.1 23.6 48.2 105.1 18.8 6.0 38.0 22.9 0.9 31.5 68.5 35.0 2.1 97.7 56.2 181.4 33.2 100.3 99.9 32.5 5.4 6.7 59.8 38.3 0.6 118.8 123.2 5.7 150.3 47.6 71.8 34.6 16.4 19.6 168.4 0.0 0.4 108.2 105.8 262.5 46.6 233.5 1.8 249.1 14.2 1.0 368.2 0.9 72.1 0.0 0.0 132.8 152.6 1.9 54.7 49.1 171.7 75.9 42.5 4.0 6.6 1.0 8.6 45.7 20.2 35.3 21.3 153.0 47.7 6.0 79.3 68.7 STXBP5 "LLGL3, tomosyn" ENSG00000164506 "Syntaxin binding protein 5" Q5T5C0 6 147204425-147390476 "Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 115.8" "Cell type enhanced" "Detected in many" "Astrocytes: 325.8;Excitatory neurons: 441.9;Inhibitory neurons: 300.1;Oligodendrocyte precursor cells: 206.1;Oligodendrocytes: 150.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "basophil: 3.8;eosinophil: 9.2;neutrophil: 3.1" "Lineage enriched" "Detected in many" 7 "granulocytes: 9.2" "Cell line enhanced" "Detected in many" "HEL: 210.2;HMC-1: 219.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039991, HPA049727, CAB079016" Enhanced Supported Enhanced Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 3: HMC-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "CAB079016: , HPA039991: AB_10673368, HPA049727: AB_2680863" "prognostic unfavorable (4.48e-4)" "unprognostic (4.60e-3)" "unprognostic (2.28e-3)" "unprognostic (1.14e-1)" "unprognostic (2.21e-1)" "unprognostic (1.52e-1)" "unprognostic (9.56e-4)" "unprognostic (6.01e-2)" "unprognostic (3.60e-1)" "unprognostic (2.74e-2)" "unprognostic (1.70e-2)" "unprognostic (6.37e-3)" "prognostic unfavorable (2.74e-7)" "unprognostic (8.01e-2)" "unprognostic (1.74e-1)" "unprognostic (2.55e-1)" "unprognostic (1.35e-3)" 7.0 9.1 7.2 9.5 12.7 34.3 7.8 24.2 13.2 9.5 0.0 14.2 8.0 8.3 7.7 13.7 5.9 9.5 5.9 9.5 6.5 3.6 3.9 6.6 7.8 0.6 0.5 5.5 15.5 115.8 7.7 6.3 0.5 11.4 16.3 20.1 5.5 14.5 7.7 15.4 11.2 10.9 0.0 8.3 8.0 22.2 0.6 9.4 6.3 8.1 9.6 8.5 9.9 8.5 10.8 9.4 4.9 16.5 23.4 48.8 5.4 24.5 36.1 17.8 19.9 8.0 7.0 7.8 5.6 48.8 30.5 12.7 14.1 21.5 21.6 17.1 11.0 210.2 27.2 9.0 26.8 72.7 219.6 35.6 15.0 35.6 72.0 42.1 23.2 12.2 57.8 9.6 35.4 15.7 11.6 18.8 4.0 8.9 21.4 1.7 25.4 3.0 9.7 18.4 10.6 7.6 18.9 13.3 8.2 8.7 3.9 28.0 26.9 25.4 9.2 12.6 22.5 7.9 0.1 9.1 14.0 26.2 18.5 3.8 0.3 9.2 0.9 0.4 0.9 0.3 0.5 1.1 0.4 0.9 0.8 1.3 3.1 0.4 0.5 0.3 0.2 0.3 7.2 12.7 24.2 13.2 9.5 6.5 0.6 0.5 0.5 0.0 0.6 8.5 12.1 16.0 8.8 325.8 5.7 3.6 2.6 1.9 3.4 38.8 6.7 7.7 14.1 11.5 6.7 16.5 31.3 5.2 9.5 18.7 0.0 4.8 39.0 10.1 10.5 10.8 41.1 10.1 441.9 12.9 4.6 10.1 14.3 20.5 44.2 5.1 8.9 4.5 4.7 33.7 300.1 30.3 0.0 7.8 3.1 42.8 7.8 7.8 10.6 97.4 8.5 5.4 6.2 206.1 150.4 11.7 21.4 7.2 5.8 10.4 29.3 1.9 2.2 29.0 13.1 12.7 5.6 13.1 11.5 11.0 6.7 3.8 9.3 5.4 19.3 3.6 SULT1C3 ENSG00000196228 "Sulfotransferase family 1C member 3" Q6IMI6 2 108239971-108265351 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 83 "breast: 368.4" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "breast cancer: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in all" "spinal cord: 36.7" HPA060368 Approved Cytosol NA NA "Cluster 5: Breast - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol "HPA060368: " "unprognostic (1.14e-3)" "unprognostic (1.78e-1)" "unprognostic (4.13e-1)" "unprognostic (6.64e-2)" 0.1 0.0 0.1 0.0 0.1 0.0 368.4 0.0 0.1 0.1 1.6 0.4 3.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.9 0.0 0.0 0.0 0.0 0.5 4.4 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 SULT1C4 "SULT1C, SULT1C2" ENSG00000198075 "Sulfotransferase family 1C member 4" O75897 2 108377911-108388989 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 13.3;Cholangiocytes: 37.1;Endothelial cells: 13.2;Granulosa cells: 15.3;Hepatic stellate cells: 17.9;Muller glia cells: 12.3;Oligodendrocyte precursor cells: 17.6" "Group enriched" "Detected in many" 6 "glioma: 7.1;renal cancer: 20.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.5;HUVEC TERT2: 10.7;SH-SY5Y: 42.0;SuSa: 11.6" "Low region specificity" "Detected in many" HPA034530 Approved Cytosol NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA034530: AB_10670170" "unprognostic (2.47e-1)" "unprognostic (1.85e-1)" "unprognostic (3.45e-1)" "unprognostic (2.89e-1)" "unprognostic (5.54e-2)" "unprognostic (1.06e-1)" "unprognostic (3.35e-2)" "unprognostic (5.77e-2)" "unprognostic (1.56e-3)" "unprognostic (1.68e-1)" "unprognostic (2.91e-2)" "unprognostic (8.45e-3)" "prognostic favorable (9.99e-7)" "unprognostic (1.79e-2)" "unprognostic (2.96e-2)" "unprognostic (1.85e-2)" "unprognostic (1.38e-1)" 6.2 2.0 15.5 1.1 16.1 0.5 5.2 16.9 17.2 21.9 12.9 3.4 1.5 11.1 8.0 2.3 9.3 27.1 10.9 13.6 18.9 18.2 3.7 10.3 1.8 18.8 27.3 27.9 2.9 1.0 5.2 13.0 20.4 6.6 2.2 8.6 1.6 8.9 3.1 0.7 3.2 5.5 18.1 1.4 2.0 1.4 19.0 5.0 4.5 6.2 1.3 3.8 5.3 15.8 0.0 0.1 9.5 0.0 0.0 0.0 1.4 0.0 0.3 0.0 0.0 4.8 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.1 0.0 1.2 0.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 42.0 0.0 0.0 0.0 11.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 15.5 16.1 16.9 17.2 13.6 18.9 18.8 27.3 20.4 18.1 19.0 15.8 13.3 0.0 0.5 10.4 0.0 0.3 0.7 0.0 0.0 2.0 0.4 0.3 0.7 37.1 0.0 9.2 0.0 0.3 0.0 0.0 0.0 0.3 5.9 10.9 3.1 13.2 0.0 2.7 0.6 0.2 0.1 4.9 0.0 3.8 0.0 15.3 17.9 0.0 0.9 1.7 0.5 0.0 0.0 1.3 1.0 1.1 1.5 0.4 0.0 7.5 0.1 12.3 0.0 17.6 0.4 0.1 0.0 4.5 1.4 0.7 0.0 7.7 0.0 1.0 0.0 1.4 1.8 0.6 0.7 0.0 0.4 0.3 0.2 7.2 0.0 0.2 SULT2A1 "DHEA-ST, STD" ENSG00000105398 "Sulfotransferase family 2A member 1" Q06520 19 47870467-47886315 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Bile acid catabolism, Lipid degradation, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 1072.1" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 1578.7" "Cancer enriched" "Detected in some" 52 "liver cancer: 244.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 2.9" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.9" "Group enriched" "Detected in some" 34 "Hep G2: 39.6;RT4: 26.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB018755, HPA041487, HPA063633" Enhanced Supported Cytosol NA NA 1200000 "Cluster 11: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Cytosol "CAB018755: AB_650242, HPA041487: AB_2677507, HPA063633: AB_2685066" "unprognostic (2.14e-1)" "unprognostic (6.79e-3)" "unprognostic (6.82e-2)" "unprognostic (1.36e-1)" "unprognostic (1.31e-2)" 0.1 235.6 0.3 0.1 0.2 0.4 0.0 0.7 0.4 0.0 0.5 0.6 59.5 0.1 0.4 0.0 0.0 0.1 0.0 0.2 0.1 0.2 1072.1 0.0 0.2 0.2 0.3 0.1 0.1 36.9 0.0 0.1 0.2 0.1 0.9 1.0 0.1 3.1 0.1 0.3 86.6 0.0 0.0 0.4 24.4 4.2 0.2 0.0 0.1 0.0 0.1 2.0 0.1 0.6 0.1 0.0 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.3 39.6 0.0 0.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.1 0.3 0.1 0.1 0.1 0.0 0.5 0.3 0.0 26.7 0.2 0.2 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.1 0.2 0.1 0.2 0.1 0.2 0.0 0.2 0.1 2.9 0.2 0.2 0.2 0.1 0.2 0.2 0.3 0.2 0.1 0.4 0.4 0.3 0.8 0.5 0.1 0.3 0.2 0.2 0.3 0.2 0.7 0.4 0.2 0.1 0.2 0.3 0.2 0.0 0.2 0.6 0.0 0.0 0.0 0.3 2.9 0.1 0.6 0.0 0.0 1.3 0.0 0.0 0.6 18.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.3 0.0 18.7 0.3 0.0 0.0 0.3 5.1 0.1 0.0 0.1 30.0 1578.7 0.0 0.0 0.3 2.8 0.0 31.8 0.4 0.2 3.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.1 0.0 8.8 0.4 0.0 0.3 171.7 0.1 0.0 2.7 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.5 1.8 81.7 2.2 0.3 SV2A "KIAA0736, SV2" ENSG00000159164 "Synaptic vesicle glycoprotein 2A" Q7L0J3 1 149903318-149917844 "FDA approved drug targets, Predicted membrane proteins" "Neurotransmitter transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 128.2;parathyroid gland: 48.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 111.9;Excitatory neurons: 63.4;Horizontal cells: 95.9;Inhibitory neurons: 107.2" "Cancer enriched" "Detected in many" 6 "glioma: 27.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 66.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002226, HPA007863" Enhanced Approved Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 62: Horizontal cells - Visual perception" Cytosol "CAB002226: AB_564144, HPA007863: AB_1080135" "unprognostic (8.05e-3)" "unprognostic (3.86e-3)" "unprognostic (2.24e-1)" "unprognostic (5.39e-2)" "unprognostic (2.66e-1)" "unprognostic (2.02e-1)" "unprognostic (6.24e-2)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (2.06e-1)" "unprognostic (9.00e-3)" "unprognostic (1.00e-1)" "prognostic unfavorable (3.22e-4)" "unprognostic (1.44e-2)" "unprognostic (9.86e-2)" "unprognostic (1.95e-2)" "unprognostic (4.81e-3)" 1.5 8.9 59.2 2.9 64.7 6.0 1.6 30.2 128.2 6.9 0.0 4.5 1.5 8.4 23.4 1.6 4.8 3.3 1.5 65.1 61.6 1.7 0.5 2.0 2.1 68.2 40.2 3.5 1.4 48.4 22.9 1.4 61.2 4.2 1.8 38.6 1.3 3.7 0.5 0.9 3.0 8.0 14.1 1.6 2.5 1.1 48.9 3.8 4.4 0.5 1.7 3.1 3.9 67.5 0.3 0.0 26.0 0.1 2.6 7.4 2.8 11.2 38.8 32.6 46.7 0.8 1.2 0.3 9.9 16.9 34.3 0.6 0.3 2.4 27.9 0.1 6.2 35.2 2.0 2.0 24.5 0.3 0.5 16.7 0.2 52.3 3.9 36.2 2.9 31.7 0.4 35.8 21.8 0.3 34.8 1.7 66.3 0.0 0.2 12.0 16.4 0.7 0.2 0.9 54.2 43.8 0.1 0.4 25.6 24.6 0.4 21.4 0.2 30.1 29.9 1.2 41.3 0.2 0.5 0.2 53.0 0.3 12.3 0.4 0.1 0.0 0.3 0.0 0.3 0.1 0.3 0.2 0.0 0.2 0.1 0.4 0.3 0.3 0.0 0.1 0.6 0.1 59.2 64.7 30.2 128.2 65.1 61.6 68.2 40.2 61.2 14.1 48.9 67.5 0.8 0.0 1.1 12.4 0.3 0.1 1.9 0.7 4.6 111.9 0.7 4.2 0.8 1.5 0.1 0.0 4.2 0.3 0.7 0.3 0.0 0.1 0.6 0.4 4.6 2.4 4.2 2.1 63.4 0.4 0.6 3.3 1.5 1.3 0.0 10.9 7.5 0.1 0.3 95.9 107.2 0.4 0.0 0.0 0.9 0.2 0.0 0.3 0.0 7.5 0.0 22.9 0.0 28.1 15.7 0.2 0.1 5.7 0.5 0.9 0.1 0.1 0.9 16.1 0.0 2.7 4.9 1.3 0.9 0.4 0.4 0.4 2.7 3.0 0.5 0.7 SWT1 "C1orf26, FLJ20121, HsSwt1" ENSG00000116668 "SWT1 RNA endoribonuclease homolog" Q5T5J6 1 185157080-185291781 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 38.3" "Cell type enhanced" "Detected in many" "Early spermatids: 150.8;Late spermatids: 52.7;Oligodendrocytes: 55.2;Spermatocytes: 54.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 14.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 18.4;U-266/84: 15.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024214, HPA027334" Enhanced Approved Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 78: Testis - Spermatogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA024214: AB_1845642, HPA027334: AB_1845643" "unprognostic (2.67e-3)" "unprognostic (1.32e-1)" "unprognostic (3.65e-1)" "unprognostic (4.26e-2)" "unprognostic (3.17e-3)" "unprognostic (8.41e-3)" "unprognostic (5.71e-3)" "unprognostic (9.26e-3)" "unprognostic (7.37e-2)" "unprognostic (2.68e-2)" "unprognostic (1.02e-1)" "unprognostic (4.28e-1)" "prognostic favorable (5.63e-4)" "unprognostic (1.97e-1)" "unprognostic (4.19e-2)" "unprognostic (4.50e-2)" "unprognostic (4.35e-2)" 3.3 3.2 4.0 2.9 5.8 9.0 4.1 4.5 3.9 3.8 3.7 3.4 4.9 4.3 4.4 2.7 2.9 3.7 3.6 3.2 5.3 4.8 3.3 3.4 2.8 5.2 5.1 6.3 9.2 4.3 2.4 5.6 5.3 4.6 3.3 5.4 6.5 3.1 2.9 3.0 3.8 3.2 4.6 3.0 4.9 38.3 4.7 4.9 5.2 4.5 3.0 3.3 2.8 7.2 2.1 1.8 5.0 2.7 8.1 6.2 4.2 2.1 3.6 2.6 3.9 1.5 1.7 2.1 4.1 1.6 2.6 1.8 3.1 2.8 3.3 5.6 2.1 2.2 1.2 2.0 4.0 0.7 1.8 4.6 2.8 2.8 2.5 4.4 6.3 4.2 4.8 10.2 2.7 0.7 2.5 1.9 5.4 5.5 1.0 1.9 4.5 5.2 2.5 1.3 1.0 7.7 1.7 2.6 7.2 11.7 2.9 1.4 3.0 3.4 2.2 3.2 1.3 18.4 15.2 0.8 3.8 1.3 1.3 14.2 1.9 2.8 1.5 1.8 2.8 2.3 3.1 2.3 1.2 3.3 2.9 2.2 5.6 0.8 4.3 1.1 6.1 1.1 4.0 5.8 4.5 3.9 3.2 5.3 5.2 5.1 5.3 4.6 4.7 7.2 7.1 3.2 1.1 37.2 4.0 1.0 2.0 1.4 2.8 4.3 5.0 3.4 7.3 2.8 3.2 5.5 4.2 3.2 2.2 5.1 0.0 2.9 150.8 5.3 4.4 4.9 0.0 8.2 25.5 2.7 6.8 5.5 4.6 4.9 2.5 4.5 7.9 3.8 3.7 8.4 32.3 3.6 0.0 5.7 1.9 52.7 4.7 3.1 1.8 21.5 3.8 2.6 4.1 31.7 55.2 2.1 7.8 5.7 5.7 2.4 4.4 5.3 2.4 5.4 0.0 4.3 5.7 54.3 11.5 3.0 0.6 6.7 3.6 2.3 2.9 2.3 SYNGR1 ENSG00000100321 "Synaptogyrin 1" O43759 22 39349925-39385575 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "melanoma: 19.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 7 "dendritic cells: 44.7;monocytes: 38.9;T-cells: 30.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029673, CAB034277" Enhanced Supported Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 6: T47d - Mammary gland" "Cluster 33: Fibroblasts - ECM organization" Cytosol "CAB034277: AB_2255766, HPA029673: AB_10670430" "unprognostic (2.68e-3)" "unprognostic (1.84e-3)" "unprognostic (5.90e-2)" "unprognostic (8.51e-2)" "unprognostic (3.74e-1)" "unprognostic (5.98e-3)" "unprognostic (7.39e-2)" "unprognostic (4.95e-2)" "unprognostic (1.83e-2)" "unprognostic (1.06e-2)" "prognostic favorable (2.41e-4)" "unprognostic (1.16e-1)" "prognostic favorable (4.98e-7)" "unprognostic (1.32e-3)" "unprognostic (1.20e-1)" "unprognostic (2.02e-2)" "unprognostic (1.04e-1)" 9.9 24.6 73.2 4.9 84.9 92.9 14.7 64.7 121.8 36.2 25.3 26.7 5.9 22.1 11.6 37.3 23.5 11.3 57.0 84.7 37.5 26.2 5.3 8.6 7.5 35.1 37.9 72.7 28.0 29.8 15.2 6.5 36.5 29.6 4.3 73.0 45.1 18.0 29.0 51.8 11.8 13.2 6.3 10.6 16.6 19.8 58.4 3.5 11.6 26.4 9.9 25.6 34.9 67.1 5.4 9.6 17.3 31.1 1.7 4.4 7.5 23.2 40.8 29.2 26.9 2.1 0.6 0.2 5.3 6.1 3.3 7.6 11.8 0.5 8.8 0.1 36.6 0.4 0.8 1.0 4.9 1.6 10.5 6.7 1.8 7.9 0.0 20.7 1.4 6.8 11.0 0.7 4.6 12.5 4.8 4.5 3.6 4.8 18.7 14.0 0.0 1.5 0.9 15.0 27.1 5.5 6.1 25.1 23.7 7.1 36.9 27.3 0.5 0.0 19.6 0.3 0.1 6.4 0.2 15.2 0.8 30.2 31.6 0.6 38.9 0.8 30.8 11.8 1.7 5.8 1.1 9.1 44.7 4.2 1.3 15.3 1.7 5.1 0.6 33.1 0.2 18.0 73.2 84.9 64.7 121.8 84.7 37.5 35.1 37.9 36.5 6.3 58.4 67.1 8.9 9.6 1.1 28.4 21.0 30.3 73.6 33.8 39.3 112.9 61.4 73.0 73.6 75.8 31.4 66.2 27.1 25.0 52.5 0.1 15.6 57.2 40.0 14.3 24.4 9.5 0.0 92.9 57.1 12.3 14.4 44.6 1.5 18.5 2.5 49.0 12.1 5.9 14.2 47.1 47.1 0.3 12.2 20.0 13.8 87.9 133.3 11.7 140.5 20.6 10.1 46.8 91.6 39.7 18.7 21.7 1.1 119.2 23.2 36.4 0.1 9.3 7.5 38.6 19.7 46.8 30.6 62.8 14.7 57.1 37.4 13.1 21.2 131.6 0.4 80.2 SYNRG "AP1GBP1, MGC104959, SYNG" ENSG00000275066 "Synergin gamma" Q9UMZ2 17 37514807-37609472 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023554, HPA023555" Approved Approved Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA023554: AB_1844892, HPA023555: AB_2058337" "unprognostic (1.22e-1)" "unprognostic (1.24e-1)" "unprognostic (9.25e-2)" "unprognostic (1.11e-1)" "unprognostic (4.99e-2)" "unprognostic (3.44e-2)" "unprognostic (3.71e-2)" "unprognostic (1.90e-1)" "unprognostic (1.40e-1)" "unprognostic (1.15e-2)" "unprognostic (2.98e-2)" "unprognostic (2.21e-2)" "unprognostic (4.68e-3)" "unprognostic (8.76e-2)" "unprognostic (2.56e-1)" "unprognostic (2.91e-2)" "prognostic favorable (3.96e-4)" 8.3 9.1 4.5 12.9 6.6 6.7 7.7 5.6 7.0 8.4 7.1 8.7 6.8 7.6 10.8 9.6 7.5 8.1 5.7 4.1 7.4 9.9 8.5 8.8 21.4 6.7 7.5 8.3 8.8 11.9 11.7 7.7 7.4 8.0 9.5 9.2 9.1 6.7 7.1 8.5 12.1 6.9 6.2 16.6 10.4 13.0 6.8 24.2 9.8 6.0 19.3 8.5 8.4 7.5 7.9 13.1 18.0 12.0 12.0 11.5 7.6 12.3 12.4 13.2 15.1 12.5 11.8 15.5 11.4 11.3 13.5 8.0 15.8 6.5 19.7 14.0 9.1 8.9 8.2 6.0 14.0 14.0 19.2 13.1 14.9 15.5 8.8 12.4 18.3 26.3 18.0 13.3 14.3 6.4 29.4 7.3 7.9 7.3 4.8 19.1 15.3 10.5 12.3 15.4 14.2 13.4 11.5 3.7 10.8 20.5 10.5 11.0 17.4 9.6 12.3 8.0 11.5 14.9 18.5 24.4 10.9 7.1 10.7 12.4 4.0 8.8 12.5 2.9 16.4 10.9 10.9 12.5 3.4 10.9 10.7 10.6 8.3 17.5 3.2 13.2 11.8 4.4 4.5 6.6 5.6 7.0 4.1 7.4 6.7 7.5 7.4 6.2 6.8 7.5 26.9 54.5 38.7 37.5 64.8 8.5 14.6 17.2 19.9 49.8 22.6 21.2 26.3 20.0 25.1 33.1 54.2 18.5 77.0 24.1 17.6 24.7 43.7 26.4 29.7 28.1 42.6 17.9 36.5 21.8 10.6 20.4 26.0 31.8 25.9 23.5 22.9 23.2 21.8 37.0 42.5 22.4 18.3 40.9 24.7 50.1 22.7 27.2 16.0 40.3 30.4 31.2 108.1 55.3 71.3 26.4 19.6 24.0 67.6 17.5 23.5 29.7 23.4 49.5 13.1 29.3 20.2 65.8 23.9 19.0 9.2 26.5 81.8 21.7 17.1 20.8 SYT16 "CHR14SYT, Strep14, SYT14L, yt14r" ENSG00000139973 "Synaptotagmin 16" Q17RD7 14 61811974-62112550 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 16.5" "Group enriched" "Detected in some" 5 "Excitatory neurons: 281.4;Inhibitory neurons: 279.7;Oligodendrocyte precursor cells: 127.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 10.8;hTERT-HME1: 4.1;PC-3: 5.4;RPTEC TERT1: 6.2;RT4: 17.0;U-2 OS: 6.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004199, HPA076871" Enhanced Approved Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 15: RT4 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA004199: AB_1080156, HPA076871: AB_2732324" "unprognostic (2.55e-2)" "unprognostic (1.43e-2)" "unprognostic (4.12e-1)" "unprognostic (8.88e-4)" "unprognostic (1.41e-1)" "unprognostic (9.08e-2)" "unprognostic (9.57e-2)" "unprognostic (9.95e-3)" "unprognostic (1.02e-1)" "unprognostic (1.38e-1)" "unprognostic (1.34e-1)" "unprognostic (3.41e-2)" "unprognostic (1.61e-2)" "unprognostic (3.06e-2)" "unprognostic (1.53e-3)" "unprognostic (2.15e-1)" 0.0 0.4 7.5 0.0 11.0 0.1 0.1 0.0 16.5 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.1 0.0 0.1 12.7 8.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.1 1.1 0.4 0.0 2.2 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.2 3.8 3.8 0.0 0.0 0.0 0.0 0.3 0.2 0.4 10.8 0.2 0.3 0.0 0.0 0.0 0.1 0.7 1.0 1.0 0.6 0.0 0.0 0.1 0.2 0.0 0.6 0.6 0.0 1.0 1.4 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 5.4 0.0 0.0 0.0 6.2 17.0 0.3 2.8 0.5 0.7 0.0 1.0 0.0 0.0 0.0 2.7 6.6 0.0 1.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 11.0 0.0 16.5 12.7 8.0 0.0 0.0 0.0 0.1 3.8 0.4 0.0 0.0 0.0 8.8 0.1 0.0 0.1 0.0 0.0 2.0 0.0 0.0 1.3 0.0 0.0 3.7 2.1 0.7 0.0 0.0 0.0 0.3 45.0 0.1 0.4 0.1 0.0 0.0 281.4 0.0 0.6 0.1 3.1 0.3 0.0 3.4 0.0 0.0 0.1 0.0 279.7 0.0 0.0 0.0 0.0 17.1 0.3 0.0 0.0 8.4 0.0 0.7 0.0 127.2 13.9 0.1 0.0 0.0 0.3 1.7 0.0 0.2 0.1 0.1 0.0 0.0 0.4 3.8 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 TACC1 ENSG00000147526 "Transforming acidic coiled-coil containing protein 1" O75410 8 38728186-38853028 "Predicted intracellular proteins" "Cell cycle, Cell division" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 554.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 34.8;granulocytes: 31.5;monocytes: 14.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017041, HPA024702, HPA056841" Approved Approved Cytosol NA NA 47000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB017041: , HPA024702: AB_1857723, HPA056841: " "unprognostic (1.83e-2)" "unprognostic (3.07e-1)" "unprognostic (2.18e-1)" "unprognostic (8.31e-2)" "unprognostic (6.55e-2)" "unprognostic (5.30e-2)" "unprognostic (1.79e-1)" "unprognostic (1.15e-1)" "unprognostic (2.47e-1)" "unprognostic (7.85e-2)" "unprognostic (1.63e-1)" "unprognostic (5.94e-2)" "prognostic favorable (1.06e-5)" "unprognostic (1.03e-3)" "unprognostic (2.84e-2)" "unprognostic (2.15e-2)" "unprognostic (1.18e-1)" 151.8 31.5 32.8 39.5 41.0 68.4 67.7 23.2 36.3 73.8 19.0 76.8 21.5 84.0 14.1 70.5 64.0 47.5 42.4 27.0 25.9 51.6 23.8 67.7 41.9 28.6 34.9 35.9 44.5 29.6 14.1 74.4 27.6 54.8 44.0 15.9 19.1 75.5 20.3 19.4 40.3 90.9 25.6 61.2 38.7 29.2 37.2 27.1 34.4 56.4 34.9 58.6 36.8 49.3 39.4 74.2 53.2 16.6 55.9 38.9 34.8 50.1 64.4 46.8 47.6 34.6 5.9 40.1 29.9 49.5 40.5 36.7 32.0 22.7 96.5 28.8 12.1 155.5 22.8 22.4 65.8 31.4 69.0 71.2 20.6 76.2 24.1 48.5 169.8 47.5 16.4 97.9 143.0 29.2 74.4 17.9 7.6 63.5 35.0 16.7 120.3 7.1 15.9 38.2 3.8 4.2 40.6 41.5 33.9 31.6 19.3 23.9 138.0 56.5 34.3 72.8 40.9 50.5 35.5 35.2 51.4 35.7 69.8 13.7 11.7 15.7 6.0 10.5 6.5 2.0 4.0 5.0 7.6 2.3 3.2 3.6 31.5 3.8 14.3 34.8 3.4 5.8 32.8 41.0 23.2 36.3 27.0 25.9 28.6 34.9 27.6 25.6 37.2 49.3 554.0 218.0 152.9 67.9 66.7 35.2 55.5 9.3 148.0 35.2 14.3 25.1 53.9 191.6 32.7 46.0 62.6 66.2 122.9 30.0 119.3 176.4 4.3 34.9 51.2 251.0 37.8 79.3 109.1 60.2 64.3 147.5 25.0 79.0 115.8 42.1 350.5 39.2 79.0 109.4 73.8 121.2 6.1 90.9 158.7 11.5 168.4 128.8 40.9 203.3 87.1 59.8 51.5 44.2 134.3 47.5 44.2 206.1 73.7 62.4 3.4 23.5 7.7 44.2 190.7 150.0 223.3 42.9 62.3 45.5 18.9 94.0 81.5 43.4 48.7 40.0 TAGAP "ARHGAP47, FLJ32631, IDDM21" ENSG00000164691 "T cell activation RhoGTPase activating protein" Q8N103 6 159034468-159045152 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 146.6;lymphoid tissue: 47.6" "Cell type enhanced" "Detected in many" "B-cells: 249.5;dendritic cells: 152.3;Macrophages: 91.1;NK-cells: 86.5;Plasma cells: 272.1;T-cells: 223.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 30.1;HMC-1: 42.5;Karpas-707: 43.8;U-266/84: 20.6;U-698: 39.6;U-937: 33.4" "Low region specificity" "Detected in all" "HPA031000, HPA039982" Uncertain Approved Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" Cytosol "HPA031000: AB_10610560, HPA039982: " "unprognostic (9.86e-3)" "unprognostic (7.55e-2)" "unprognostic (2.41e-2)" "unprognostic (1.56e-2)" "unprognostic (6.36e-2)" "unprognostic (3.10e-3)" "unprognostic (1.04e-1)" "unprognostic (5.25e-2)" "unprognostic (3.35e-3)" "unprognostic (8.39e-2)" "unprognostic (6.19e-2)" "unprognostic (2.41e-1)" "unprognostic (1.49e-1)" "unprognostic (7.25e-2)" "unprognostic (1.15e-1)" "unprognostic (5.24e-2)" "unprognostic (7.39e-2)" 5.0 2.8 1.0 28.9 1.1 146.6 3.9 1.3 2.1 3.4 3.0 5.9 4.4 9.5 2.3 4.1 2.0 6.9 1.6 1.2 3.4 1.3 4.1 8.4 39.6 2.7 2.0 2.2 0.9 0.7 0.8 3.4 2.1 2.8 8.2 1.5 3.0 1.8 0.7 1.2 10.2 26.0 2.2 22.8 7.2 1.6 2.2 24.3 1.6 2.3 47.6 10.0 1.2 4.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 30.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 6.2 0.0 0.0 0.0 15.6 42.5 0.3 0.0 0.0 0.0 0.0 0.0 9.0 0.1 43.8 0.0 0.0 4.0 8.2 12.0 0.0 0.0 1.4 0.0 1.4 0.0 0.0 0.3 0.2 0.0 0.1 0.1 1.2 0.0 6.9 0.2 0.0 0.0 0.0 0.0 4.7 20.6 39.6 0.0 33.4 0.0 163.6 27.8 88.4 54.8 20.4 62.6 45.9 73.9 64.6 27.9 46.6 56.9 40.8 169.7 45.6 27.6 9.3 57.5 60.9 1.0 1.1 1.3 2.1 1.2 3.4 2.7 2.0 2.1 2.2 2.2 4.2 5.2 3.2 6.6 0.0 249.5 2.8 0.3 0.2 3.4 0.3 4.4 6.0 0.6 0.0 1.4 0.0 0.0 0.7 152.3 0.2 0.0 0.1 0.3 0.5 0.4 5.2 0.0 8.8 1.2 0.0 0.6 4.3 16.8 0.5 19.0 1.8 1.4 0.8 24.9 0.0 1.0 0.0 0.0 21.9 60.2 1.1 1.2 91.1 28.4 20.6 21.5 0.4 86.5 1.5 0.0 0.0 0.0 22.6 272.1 0.3 0.0 0.3 1.2 0.2 0.0 0.8 2.0 0.1 0.1 2.0 2.7 0.8 223.6 4.6 0.4 0.3 TAL2 bHLHa19 ENSG00000186051 "TAL bHLH transcription factor 2" Q16559 9 105662457-105663124 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "skeletal muscle: 13.7" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 4.2;Distal tubular cells: 7.9;Enteroendocrine cells: 3.5;Muller glia cells: 2.7;Proximal tubular cells: 2.3" "Group enriched" "Detected in some" 4 "renal cancer: 1.6;testis cancer: 0.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory B-cell: 6.9;naive B-cell: 7.3" "Lineage enriched" "Detected in many" 4 "B-cells: 7.3" "Cell line enhanced" "Detected in some" "CACO-2: 2.1;HAP1: 2.9;K-562: 8.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA030886 Uncertain Approved Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA030886: AB_10601596" "unprognostic (3.89e-2)" "unprognostic (1.45e-1)" "unprognostic (8.51e-2)" "unprognostic (5.54e-2)" "unprognostic (2.24e-1)" "unprognostic (9.06e-2)" "unprognostic (4.98e-2)" "unprognostic (1.03e-1)" "unprognostic (2.70e-3)" "unprognostic (2.63e-1)" "unprognostic (7.00e-4)" "unprognostic (2.84e-2)" "prognostic favorable (2.69e-4)" "unprognostic (2.70e-2)" "unprognostic (1.24e-1)" "unprognostic (1.29e-1)" "unprognostic (7.39e-2)" 0.1 0.2 0.4 0.1 0.5 0.0 0.1 0.3 0.9 0.2 1.3 0.1 0.0 0.1 0.6 0.1 0.2 0.0 0.2 0.5 0.5 3.0 0.2 0.1 0.2 0.5 0.6 0.3 0.1 0.0 0.4 0.1 0.6 0.1 0.1 0.5 0.1 0.1 13.7 0.1 0.1 0.0 0.4 0.2 0.1 0.3 0.4 0.1 0.1 2.4 0.3 0.1 0.1 0.7 0.0 0.4 1.5 0.4 0.1 0.0 0.1 0.1 0.1 0.1 0.2 2.1 0.1 0.0 0.1 0.0 0.4 0.0 2.9 0.0 0.1 0.4 0.3 0.7 0.0 0.0 0.1 0.3 1.1 0.1 0.3 0.1 0.1 0.1 0.0 0.5 8.2 0.2 0.2 0.2 0.5 0.4 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.7 0.7 0.1 0.1 0.1 0.0 0.2 1.3 0.3 0.2 0.4 0.4 0.6 0.6 1.2 0.0 0.1 1.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.1 0.4 0.5 0.3 0.9 0.5 0.5 0.5 0.6 0.6 0.4 0.4 0.7 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.0 0.4 0.1 0.2 0.0 0.0 0.0 4.2 0.0 0.1 0.0 7.9 0.1 0.1 0.0 0.2 0.0 3.5 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 2.7 0.0 0.0 0.2 0.2 0.0 0.4 0.1 0.0 0.0 2.3 0.0 1.0 0.0 0.8 0.1 0.6 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 TAMM41 "C3orf31, DKFZp434E0519, MGC16471" ENSG00000144559 "TAM41 mitochondrial translocator assembly and maintenance homolog" Q96BW9 3 11790442-11846919 "Enzymes, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036834, HPA044861" Uncertain Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA036834: AB_10672270, HPA044861: AB_2679116" "unprognostic (2.40e-2)" "unprognostic (4.41e-2)" "prognostic favorable (1.23e-4)" "unprognostic (4.45e-2)" "unprognostic (1.44e-2)" "unprognostic (5.60e-2)" "unprognostic (2.03e-5)" "unprognostic (1.57e-1)" "unprognostic (2.35e-1)" "unprognostic (3.95e-1)" "unprognostic (1.60e-1)" "unprognostic (7.33e-3)" "unprognostic (3.78e-2)" "unprognostic (2.04e-1)" "unprognostic (1.63e-1)" "unprognostic (7.34e-2)" "unprognostic (3.59e-3)" 8.3 7.4 5.8 5.6 6.2 4.3 8.0 6.4 8.5 8.0 2.6 6.5 4.9 7.2 9.7 9.0 6.9 4.1 8.0 5.3 6.9 6.7 5.5 5.0 7.1 3.9 4.1 11.0 5.6 5.8 5.6 4.1 4.0 5.2 4.9 6.3 6.8 4.5 9.2 10.1 6.2 6.2 2.8 6.5 6.0 5.7 5.4 6.5 6.0 5.2 7.8 8.4 8.2 6.2 6.2 11.3 13.5 9.4 14.3 18.0 24.9 9.3 6.6 13.9 13.8 13.6 9.9 23.4 13.3 9.8 6.2 7.4 22.9 13.9 17.9 8.8 21.6 14.0 10.6 15.9 16.7 25.8 7.1 10.3 20.3 13.1 14.6 9.1 21.8 18.3 20.8 7.0 18.0 17.8 14.6 19.2 10.9 9.6 23.8 14.4 7.7 20.7 21.6 14.8 6.2 5.4 8.1 10.3 16.6 15.1 13.5 11.6 5.7 7.2 8.3 21.8 13.5 5.4 14.2 12.1 8.8 21.8 6.7 1.9 4.5 7.1 5.7 3.2 7.6 7.5 9.1 5.8 7.8 7.1 8.4 8.8 0.2 6.9 6.7 5.8 7.7 4.8 5.8 6.2 6.4 8.5 5.3 6.9 3.9 4.1 4.0 2.8 5.4 6.2 9.4 6.4 7.0 24.5 11.4 4.2 8.1 15.7 5.7 11.5 5.5 8.3 8.9 0.0 8.7 3.7 12.5 12.2 8.6 3.3 9.8 10.1 2.2 5.4 9.2 7.6 3.0 9.4 34.5 9.3 11.0 7.2 6.6 4.4 2.5 10.5 5.7 5.8 9.2 10.1 34.7 8.1 12.2 6.4 6.4 1.5 7.8 6.8 3.6 14.0 5.9 11.0 10.3 34.7 32.0 7.9 3.4 6.4 7.1 6.7 4.2 10.3 11.8 14.7 0.0 8.6 8.7 7.4 12.4 6.6 4.1 7.0 9.5 10.8 7.3 5.9 TANC2 "DKFZP564D166, FLJ10215, FLJ11824, KIAA1148, KIAA1636, rols, ROLSA" ENSG00000170921 "Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2" Q9HCD6 17 63009556-63427699 "Disease related genes, Predicted intracellular proteins" "Autism spectrum disorder, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 30.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 597.7;Granulosa cells: 195.7;Inhibitory neurons: 394.9;Oligodendrocyte precursor cells: 641.4;Oligodendrocytes: 329.8" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 11.2;basal ganglia: 27.6;cerebral cortex: 22.3;hippocampal formation: 15.9;white matter: 17.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023274 Uncertain Approved Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA023274: AB_2199727" "unprognostic (8.37e-2)" "unprognostic (4.15e-2)" "unprognostic (2.21e-2)" "unprognostic (1.57e-4)" "unprognostic (1.51e-1)" "unprognostic (4.09e-2)" "unprognostic (9.26e-2)" "unprognostic (1.83e-1)" "unprognostic (8.09e-2)" "unprognostic (5.52e-2)" "unprognostic (2.62e-1)" "unprognostic (2.69e-1)" "unprognostic (2.02e-2)" "unprognostic (5.15e-2)" "unprognostic (1.47e-1)" "unprognostic (1.57e-1)" "unprognostic (2.01e-1)" 5.8 6.4 11.2 2.9 27.6 12.0 5.6 0.0 22.3 6.8 0.0 4.2 2.0 5.1 8.3 6.1 4.2 5.4 5.1 15.9 2.8 6.3 2.2 12.5 1.5 1.6 0.0 4.4 4.2 30.5 10.4 4.1 4.3 6.1 2.0 6.4 7.3 5.3 2.2 11.1 2.5 7.0 1.3 2.5 3.8 18.4 1.1 3.4 3.7 2.5 1.7 8.3 7.0 17.5 28.2 25.9 15.8 2.7 7.9 19.0 30.5 17.6 17.3 17.0 21.0 1.5 8.0 0.0 5.3 30.3 21.6 3.8 25.6 51.6 38.2 10.9 11.8 41.0 38.9 1.5 6.9 11.2 0.0 29.3 29.5 19.9 56.9 18.8 5.5 10.4 5.2 0.0 24.6 21.4 7.4 1.8 1.8 4.9 16.8 5.7 31.7 2.1 15.1 38.4 26.5 29.2 9.8 18.3 7.2 27.3 8.4 2.9 28.0 41.3 21.4 2.7 21.7 0.0 0.0 0.0 15.2 2.9 15.1 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.3 0.4 0.0 0.3 0.1 0.2 0.3 0.9 0.0 0.4 0.0 0.0 11.2 27.6 0.0 22.3 15.9 2.8 1.6 0.0 4.3 1.3 1.1 17.5 13.2 16.0 59.4 79.0 2.3 25.1 13.0 25.3 6.8 63.1 11.6 8.5 3.9 10.0 19.2 27.6 16.7 8.0 9.4 3.4 1.9 10.9 17.5 15.4 12.6 12.3 4.2 3.8 597.7 14.0 35.0 8.5 7.7 19.7 0.0 195.7 24.3 1.3 7.3 8.4 394.9 3.3 20.3 9.7 10.9 10.4 5.6 16.7 10.6 151.8 11.2 3.9 14.4 641.4 329.8 29.4 2.8 3.4 2.9 10.6 0.3 1.7 10.2 7.1 19.7 62.9 6.9 23.0 20.4 10.8 15.9 16.4 9.9 8.8 2.2 11.8 TARS3 "FLJ25005, TARSL2, ThrRS-L" ENSG00000185418 "Threonyl-tRNA synthetase 3" A2RTX5 15 101653596-101724473 "Enzymes, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 33.8;skeletal muscle: 38.5;tongue: 36.7" "Cell type enhanced" "Detected in some" "Adipocytes: 7.7;B-cells: 9.5;Cardiomyocytes: 41.0;dendritic cells: 27.6;Plasma cells: 19.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066697 Enhanced Approved Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA066697: AB_2685705" "unprognostic (9.33e-3)" "unprognostic (2.13e-2)" "unprognostic (1.88e-1)" "unprognostic (2.54e-1)" "unprognostic (8.44e-2)" "unprognostic (1.92e-1)" "unprognostic (8.45e-2)" "unprognostic (3.40e-2)" "unprognostic (3.24e-2)" "unprognostic (7.77e-2)" "unprognostic (2.26e-3)" "unprognostic (9.76e-3)" "unprognostic (4.00e-2)" "unprognostic (2.23e-1)" "unprognostic (7.52e-2)" "unprognostic (6.48e-3)" "unprognostic (2.79e-2)" 4.9 4.2 16.1 4.1 24.8 3.1 4.6 20.1 21.1 6.4 9.0 7.9 3.8 4.3 3.5 3.8 5.2 3.4 15.2 14.7 18.4 5.2 3.6 3.7 4.7 20.0 19.8 6.9 6.4 7.5 6.3 1.9 20.2 5.7 3.7 6.2 4.9 5.9 38.5 3.3 6.2 4.2 17.5 4.4 5.7 3.5 19.1 4.2 6.2 36.7 4.7 6.9 4.6 33.8 2.5 4.6 7.9 4.3 8.4 6.4 3.9 8.6 5.8 6.5 4.0 6.8 2.2 3.3 3.3 10.3 5.3 7.6 13.8 4.9 6.0 3.8 22.0 8.1 2.9 5.5 3.9 3.8 1.7 4.5 4.6 3.2 3.7 7.7 4.7 7.0 8.0 6.9 6.6 4.3 2.0 7.4 9.5 12.5 3.3 4.1 12.0 8.6 5.7 2.7 12.5 8.2 11.5 4.5 5.1 14.5 2.9 8.0 6.4 3.2 7.4 6.4 2.8 9.6 11.5 4.1 8.2 6.6 5.9 0.8 1.0 1.5 2.7 1.5 2.7 4.9 5.0 4.3 0.7 7.5 4.9 2.6 0.2 7.9 0.7 1.7 0.9 1.1 16.1 24.8 20.1 21.1 14.7 18.4 20.0 19.8 20.2 17.5 19.1 33.8 7.7 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.0 0.0 0.0 0.0 0.0 3.3 27.6 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 5.8 5.4 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 4.2 7.3 0.0 0.0 0.0 TBC1D2B KIAA1055 ENSG00000167202 "TBC1 domain family member 2B" Q9UPU7 15 77984036-78077724 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 90.7;Theca cells: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041833, HPA048174, HPA052663" Approved Enhanced Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" Cytosol "HPA041833: AB_2732494, HPA048174: AB_2680297, HPA052663: AB_2681906" "unprognostic (3.13e-1)" "unprognostic (2.16e-1)" "unprognostic (8.25e-2)" "unprognostic (1.28e-2)" "unprognostic (3.94e-2)" "unprognostic (1.43e-1)" "unprognostic (5.07e-3)" "unprognostic (2.41e-1)" "unprognostic (1.08e-1)" "unprognostic (8.22e-3)" "unprognostic (2.21e-1)" "unprognostic (1.25e-1)" "unprognostic (1.23e-3)" "unprognostic (6.68e-2)" "unprognostic (3.07e-2)" "unprognostic (3.37e-1)" "unprognostic (3.19e-2)" 23.1 15.4 4.8 20.4 5.1 22.5 17.3 4.6 5.0 25.1 9.3 15.8 12.9 23.3 11.7 11.4 20.8 28.2 10.2 4.1 6.6 7.7 16.3 33.9 23.1 9.7 5.5 46.1 18.3 17.1 5.9 25.0 6.0 11.5 17.4 4.5 8.7 14.3 5.1 13.4 16.0 21.2 6.3 25.5 12.9 12.6 6.7 23.8 12.1 10.8 19.3 19.1 14.9 6.6 12.0 9.4 11.1 10.5 76.2 60.4 19.3 27.1 40.7 24.9 27.3 12.0 4.8 18.5 10.6 23.0 13.8 17.1 24.4 29.9 18.9 35.2 18.8 11.8 9.1 8.2 36.1 30.1 17.3 59.2 20.4 16.5 11.0 36.8 28.6 23.5 6.2 12.5 32.5 13.2 11.2 19.7 8.8 9.3 9.0 16.8 50.9 4.1 12.7 45.1 5.9 16.0 25.3 17.0 31.9 10.2 5.6 31.1 35.5 27.1 17.8 8.6 14.5 20.9 23.8 9.7 9.3 39.8 14.6 0.0 0.8 0.3 1.4 0.6 0.8 0.0 0.9 1.6 0.5 0.1 0.7 0.6 1.4 1.4 0.2 1.2 0.5 0.6 4.8 5.1 4.6 5.0 4.1 6.6 9.7 5.5 6.0 6.3 6.7 6.6 13.9 3.2 17.3 26.4 6.4 9.3 7.3 13.9 1.8 10.7 5.3 4.3 3.3 14.3 9.7 5.5 6.2 20.6 24.0 12.8 0.0 8.8 10.0 7.1 33.7 16.1 7.3 4.4 23.3 10.0 6.9 28.0 17.3 6.3 9.5 6.3 21.4 90.7 19.0 15.2 20.3 19.7 10.2 31.9 29.3 10.3 42.6 21.5 14.2 45.9 23.7 6.2 6.2 12.5 10.4 15.3 13.4 42.2 9.5 6.3 15.3 4.3 10.9 8.9 26.3 19.4 18.2 6.0 7.1 4.5 9.9 28.5 26.0 79.0 15.7 8.1 TBC1D4 "AS160, DKFZp779C0666, KIAA0603" ENSG00000136111 "TBC1 domain family member 4" O60343 13 75283503-75482169 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "GTPase activation" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 82.8" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 157.7;Microglial cells: 307.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 25.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 84.7;HUVEC TERT2: 61.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040145, HPA059885" Approved Supported Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA040145: AB_2676860, HPA059885: AB_2684152" "unprognostic (5.44e-3)" "unprognostic (5.23e-1)" "unprognostic (9.85e-2)" "unprognostic (1.39e-1)" "unprognostic (2.78e-2)" "unprognostic (9.54e-3)" "unprognostic (1.25e-2)" "unprognostic (8.87e-2)" "unprognostic (2.87e-1)" "unprognostic (5.02e-2)" "unprognostic (7.53e-2)" "unprognostic (2.64e-1)" "prognostic favorable (1.07e-11)" "unprognostic (6.40e-2)" "unprognostic (3.16e-1)" "unprognostic (8.88e-2)" "unprognostic (3.45e-1)" 14.8 70.6 13.2 15.7 12.5 3.4 20.1 12.5 15.1 10.0 7.1 8.7 4.6 8.5 18.4 9.4 10.7 14.1 33.8 10.5 13.8 25.2 11.7 11.9 34.2 15.9 12.0 44.8 15.0 22.1 5.3 20.7 16.7 12.3 10.4 1.6 27.6 4.3 82.8 21.4 10.3 10.2 12.0 21.0 11.0 5.3 20.0 10.7 24.3 54.9 32.6 8.4 9.2 10.5 12.9 14.9 9.2 0.6 21.3 22.8 12.0 11.0 5.8 8.7 9.6 84.7 15.5 2.7 2.4 15.7 4.2 12.0 23.4 11.0 9.0 42.6 24.3 41.5 19.8 25.9 5.4 20.0 0.5 25.0 19.7 9.7 22.4 14.9 61.6 46.0 12.0 1.3 10.0 6.2 29.4 3.6 12.9 24.7 8.8 26.4 8.7 15.2 8.5 9.3 16.9 5.2 4.8 14.6 8.0 4.8 5.0 0.7 26.2 9.8 12.1 5.2 13.0 0.7 0.1 0.3 17.4 18.5 14.7 5.0 0.4 0.0 0.7 0.1 0.0 0.6 11.2 2.5 0.6 0.5 10.4 4.9 0.5 0.5 0.1 9.9 25.0 2.3 13.2 12.5 12.5 15.1 10.5 13.8 15.9 12.0 16.7 12.0 20.0 10.5 17.8 6.4 29.1 32.3 2.6 36.2 10.0 2.0 19.9 1.6 33.1 41.1 81.4 10.0 6.1 14.7 0.0 10.8 32.4 8.0 15.6 12.3 25.5 14.3 17.7 32.6 21.0 5.0 78.0 7.4 9.7 17.3 7.1 8.7 5.1 81.5 26.0 19.4 26.6 1.7 157.7 10.7 24.4 24.8 25.8 5.2 3.7 12.9 21.4 307.3 33.6 0.4 1.0 40.7 5.1 4.9 2.9 7.2 2.1 16.4 3.4 10.8 3.9 0.6 6.6 24.8 21.6 2.4 7.7 24.2 44.2 4.9 25.2 8.1 15.5 10.6 TBC1D8B "FLJ20298, GRAMD8B, RP11-321G1.1" ENSG00000133138 "TBC1 domain family member 8B" Q0IIM8 X 106802673-106876150 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 230.8;Alveolar cells type 2: 234.5;Club cells: 92.9;granulocytes: 113.0;Respiratory ciliated cells: 108.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023883, HPA027527" Enhanced Approved Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 11: Alveolar cells - Smell perception" Cytosol "HPA023883: AB_1857794, HPA027527: AB_2199395" "unprognostic (6.69e-2)" "unprognostic (1.06e-1)" "unprognostic (8.19e-2)" "unprognostic (4.69e-3)" "unprognostic (8.15e-2)" "unprognostic (6.97e-2)" "unprognostic (2.08e-1)" "unprognostic (1.88e-2)" "unprognostic (1.48e-1)" "unprognostic (1.94e-1)" "unprognostic (2.75e-1)" "unprognostic (4.89e-2)" "unprognostic (3.32e-2)" "unprognostic (4.77e-2)" "unprognostic (1.62e-1)" "unprognostic (9.97e-2)" "unprognostic (5.16e-2)" 4.5 19.6 5.8 4.2 11.5 5.2 4.6 15.3 19.6 6.9 15.0 6.3 7.8 5.4 10.0 3.0 3.9 7.0 3.4 8.0 5.1 8.4 12.0 4.5 2.7 2.0 1.5 6.4 9.0 8.6 6.4 4.5 3.6 6.8 7.3 9.6 7.7 6.4 3.1 4.1 9.5 5.1 0.5 3.2 11.0 8.5 5.9 1.6 8.8 1.6 2.0 4.5 2.5 24.4 14.7 4.6 1.8 7.1 21.9 30.9 7.9 16.3 16.9 2.8 8.5 8.1 12.6 5.1 12.9 16.6 11.6 7.6 5.9 8.2 7.2 2.5 6.5 7.1 6.4 7.7 5.7 1.8 2.6 13.7 6.5 6.0 2.9 17.2 7.9 4.1 2.4 8.3 10.0 7.4 4.6 2.7 9.2 21.6 7.3 2.0 3.9 2.1 7.9 10.7 3.3 2.7 13.4 9.7 6.0 9.1 11.0 2.2 10.0 10.4 11.2 13.9 6.0 7.6 8.4 1.3 20.2 1.5 13.1 2.1 0.8 0.4 0.7 0.4 0.5 0.7 0.6 0.5 0.2 1.4 0.4 0.5 1.9 0.5 0.4 1.0 0.2 0.1 5.8 11.5 15.3 19.6 8.0 5.1 2.0 1.5 3.6 0.5 5.9 24.4 7.0 230.8 234.5 1.0 2.2 2.4 7.8 8.4 7.4 4.1 6.9 3.3 2.6 4.3 92.9 7.3 4.2 2.8 0.6 9.5 7.9 8.8 0.9 4.9 12.5 19.2 4.8 1.3 8.3 9.3 3.0 25.2 21.9 6.8 113.0 4.8 3.3 13.5 1.7 0.0 7.5 15.1 6.1 2.2 0.4 2.2 9.0 12.7 3.6 14.0 1.0 1.8 1.0 13.6 25.4 6.1 9.2 8.6 0.2 8.0 14.0 12.1 108.3 3.6 0.0 8.3 5.7 3.6 3.2 3.5 1.4 2.6 9.4 31.4 10.1 10.3 TBC1D9 "GRAMD9, KIAA0882, MDR1" ENSG00000109436 "TBC1 domain family member 9" Q6ZT07 4 140620782-140756385 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 91.6" "Cancer enriched" "Detected in all" 7 "breast cancer: 85.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 5.9" "Group enriched" "Detected in many" 37 "B-cells: 5.9;dendritic cells: 3.2;monocytes: 1.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000262, HPA006503" Uncertain Approved Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 19: Lung - Lung function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 35: Glandular cells - Unknown function" Cytosol "HPA000262: AB_2665956, HPA006503: AB_2667604" "unprognostic (1.41e-1)" "unprognostic (1.35e-2)" "unprognostic (2.41e-1)" "unprognostic (6.49e-2)" "unprognostic (3.00e-1)" "unprognostic (1.22e-2)" "unprognostic (9.17e-2)" "unprognostic (2.11e-3)" "unprognostic (2.64e-1)" "unprognostic (2.66e-1)" "unprognostic (2.96e-3)" "unprognostic (6.77e-2)" "prognostic favorable (1.61e-6)" "unprognostic (2.17e-2)" "unprognostic (1.11e-1)" "unprognostic (6.72e-2)" "unprognostic (2.16e-2)" 18.2 9.2 7.2 15.2 7.9 2.0 48.7 22.5 9.4 12.9 35.2 7.3 8.2 8.3 7.8 9.1 10.0 13.8 8.5 8.4 15.3 15.7 12.6 16.3 15.1 7.9 9.6 15.9 9.1 9.8 6.3 20.5 15.4 14.6 6.6 21.0 8.8 21.3 2.2 3.2 12.8 7.7 6.4 33.7 16.8 3.3 12.9 5.6 5.8 6.9 19.4 15.8 7.1 3.3 0.9 11.9 10.9 9.4 26.0 24.3 22.3 15.3 16.3 10.8 13.7 2.4 10.4 0.1 9.5 19.9 13.4 2.4 13.7 10.8 10.1 0.0 7.7 7.0 8.5 10.4 9.4 0.9 1.1 20.1 17.7 9.4 37.2 31.2 30.3 3.7 0.0 0.0 10.2 12.0 1.6 0.1 1.7 12.7 10.4 7.7 17.9 18.1 12.3 22.0 16.0 11.4 15.8 27.4 10.5 18.4 6.4 0.4 47.7 28.3 8.5 18.6 13.3 0.0 0.0 0.1 17.2 1.3 15.7 0.0 1.7 0.0 0.0 1.3 0.0 5.9 0.0 0.0 2.9 2.9 0.0 0.0 0.0 0.0 0.5 3.2 0.0 0.7 7.2 7.9 22.5 9.4 8.4 15.3 7.9 9.6 15.4 6.4 12.9 3.3 49.4 54.5 9.3 4.6 42.1 4.6 10.6 21.4 4.0 35.4 91.6 39.4 8.1 17.2 15.1 55.2 4.2 14.1 14.0 8.3 7.9 13.6 0.5 49.4 20.9 32.6 7.7 0.4 54.8 17.2 4.7 15.1 8.2 61.4 0.0 8.0 17.2 23.9 18.3 10.1 66.2 6.6 24.4 39.3 30.3 1.3 13.1 44.8 8.8 78.7 39.5 43.5 1.0 27.6 2.6 12.2 5.8 26.7 25.0 16.3 6.1 5.7 15.9 7.6 0.0 2.8 11.1 0.8 1.7 10.4 3.8 43.2 3.7 16.0 3.1 16.0 TBCB "CG22, CKAP1, CKAPI" ENSG00000105254 "Tubulin folding cofactor B" Q99426 19 36114289-36125947 "Metabolic proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Chaperone, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 448.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041428, HPA041722" Approved Supported Cytosol NA NA 120000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA041428: AB_10794517, HPA041722: AB_10804007" "unprognostic (3.88e-3)" "unprognostic (3.05e-1)" "unprognostic (8.52e-2)" "unprognostic (1.38e-2)" "unprognostic (7.94e-2)" "unprognostic (1.25e-2)" "prognostic unfavorable (2.09e-4)" "unprognostic (1.15e-2)" "unprognostic (5.19e-2)" "unprognostic (1.32e-1)" "prognostic favorable (3.11e-4)" "unprognostic (4.54e-2)" "unprognostic (6.34e-3)" "unprognostic (9.20e-2)" "unprognostic (6.11e-2)" "unprognostic (5.39e-2)" "unprognostic (1.02e-1)" 83.7 83.8 332.0 49.9 365.5 52.8 77.9 365.7 448.6 95.6 289.2 102.5 34.9 117.6 33.0 83.3 88.7 31.0 109.5 332.5 357.6 92.0 57.5 73.3 52.1 368.9 354.4 89.6 44.8 47.5 116.3 36.6 370.0 67.4 29.8 62.3 51.6 46.8 87.8 58.7 66.6 48.0 356.8 76.1 69.7 89.4 359.9 53.3 58.8 49.5 42.3 99.7 82.0 412.4 119.8 361.0 122.7 89.0 84.2 83.4 54.8 95.6 72.6 158.0 111.5 161.0 62.0 99.4 167.4 144.9 114.3 59.0 99.8 102.6 84.0 231.4 127.9 85.5 89.4 224.9 104.7 96.6 166.8 97.6 74.7 123.9 76.4 105.7 102.5 139.7 39.7 141.1 125.3 189.2 152.6 117.5 83.0 137.8 139.8 135.2 69.5 93.2 137.9 108.3 139.6 153.0 89.3 112.2 102.9 109.2 58.7 120.2 106.5 156.9 166.9 91.3 181.4 70.9 182.3 113.1 140.7 99.2 87.5 310.8 240.3 318.5 286.0 335.8 190.5 258.8 260.4 249.5 265.2 246.6 155.9 195.5 103.8 246.1 409.3 280.2 386.5 358.2 332.0 365.5 365.7 448.6 332.5 357.6 368.9 354.4 370.0 356.8 359.9 412.4 110.6 60.9 29.7 13.1 76.9 66.9 89.8 170.1 56.9 61.3 73.5 98.9 53.5 58.6 90.9 138.0 12.5 136.7 111.5 64.8 180.0 147.2 143.5 88.7 85.6 100.9 107.2 52.4 14.0 111.8 212.5 93.0 53.0 80.5 83.7 99.4 80.7 33.7 160.5 72.3 14.9 58.4 160.7 70.9 154.0 274.0 90.1 95.8 129.9 13.1 239.2 127.8 142.2 11.6 68.3 129.8 95.3 101.2 53.3 61.7 63.1 188.4 115.8 85.6 65.7 75.6 195.8 108.3 156.9 71.7 67.6 82.6 114.3 88.2 56.7 78.5 TBCC CFC ENSG00000124659 "Tubulin folding cofactor C" Q15814 6 42744498-42746103 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035073, HPA035074" Approved Supported Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 21: OE19 - Mitochondria" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA035073: AB_10602897, HPA035074: AB_2674448" "unprognostic (7.16e-2)" "unprognostic (9.88e-2)" "unprognostic (2.17e-1)" "unprognostic (4.23e-2)" "unprognostic (8.20e-2)" "unprognostic (6.79e-2)" "unprognostic (5.80e-3)" "unprognostic (1.41e-2)" "unprognostic (2.47e-1)" "unprognostic (3.96e-3)" "unprognostic (1.84e-2)" "unprognostic (1.92e-1)" "unprognostic (2.22e-1)" "unprognostic (2.28e-1)" "unprognostic (1.29e-1)" "unprognostic (6.31e-2)" "unprognostic (3.76e-3)" 10.4 15.0 15.9 17.8 15.8 39.6 9.9 15.4 18.3 9.9 12.3 17.0 14.5 14.4 12.9 16.1 15.6 10.1 16.0 16.4 16.3 11.9 13.1 11.6 29.1 18.0 14.1 12.2 14.9 11.3 11.1 7.6 18.8 11.3 9.9 15.4 14.5 11.8 26.7 16.8 23.5 10.7 15.2 30.1 15.5 18.0 14.7 21.9 14.0 14.4 19.5 13.1 10.0 16.6 34.5 11.2 16.9 31.7 23.9 16.0 22.3 23.2 26.1 25.3 27.4 17.4 13.3 31.0 18.3 22.7 21.0 29.5 22.9 23.2 14.0 17.0 25.0 16.3 16.7 29.7 27.2 17.9 25.5 26.2 27.8 19.7 16.1 22.7 20.1 17.1 37.8 27.4 22.9 42.4 14.8 34.3 15.8 93.5 30.4 14.8 20.3 20.3 24.5 18.6 64.7 28.1 15.1 25.8 41.1 15.4 28.3 59.7 21.9 24.1 21.6 19.6 32.3 36.1 43.7 53.0 11.8 24.2 23.7 139.1 91.4 174.5 105.5 79.2 108.9 101.7 111.9 116.7 83.5 90.9 129.6 119.9 162.1 170.8 74.1 142.3 154.8 170.4 15.9 15.8 15.4 18.3 16.4 16.3 18.0 14.1 18.8 15.2 14.7 16.6 19.3 3.2 24.0 2.6 50.8 25.1 25.9 49.3 51.2 55.0 25.4 29.1 6.8 24.3 25.7 11.0 41.7 21.4 83.8 25.1 33.2 38.6 30.3 23.0 21.2 20.9 45.3 13.0 7.0 30.9 23.5 17.1 18.3 22.9 31.0 21.0 19.6 10.0 18.8 18.5 7.8 21.2 71.2 16.2 27.8 10.2 17.7 15.9 28.4 8.4 33.6 46.3 77.2 5.0 12.8 28.5 27.0 20.7 37.1 15.9 29.8 23.9 22.0 51.7 19.7 13.0 46.1 50.1 22.7 30.7 24.9 21.1 80.2 26.6 22.3 22.1 TBCEL "LRRC35, MGC10233" ENSG00000154114 "Tubulin folding cofactor E like" Q5QJ74 11 121024072-121090775 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 104.0;Oligodendrocytes: 39.4;Plasma cells: 42.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "HPA038593, HPA038594" Approved Uncertain Cytosol NA NA 22000 "Cluster 48: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 6: Erythroid cells - Oxygen transport" Cytosol "HPA038593: AB_10669647, HPA038594: AB_2676103" "unprognostic (9.06e-3)" "unprognostic (3.42e-2)" "unprognostic (2.65e-1)" "unprognostic (2.29e-1)" "unprognostic (5.80e-2)" "unprognostic (3.13e-1)" "unprognostic (1.22e-1)" "unprognostic (2.55e-2)" "unprognostic (1.27e-2)" "unprognostic (1.06e-2)" "unprognostic (4.20e-2)" "unprognostic (3.14e-1)" "unprognostic (8.55e-2)" "unprognostic (3.07e-3)" "unprognostic (1.86e-1)" "unprognostic (1.66e-2)" "unprognostic (1.02e-1)" 7.4 7.6 10.7 5.9 14.2 5.6 9.0 14.4 11.5 7.2 15.0 7.4 5.4 8.5 9.6 5.7 6.2 7.7 9.8 8.5 11.0 8.3 15.1 9.6 7.5 10.5 10.5 9.2 6.3 16.5 7.9 10.8 9.8 9.0 5.9 8.3 7.2 12.3 6.1 5.1 5.8 9.6 10.2 8.4 6.0 14.8 14.2 7.2 10.3 8.2 7.4 6.6 4.7 13.6 6.2 5.8 9.8 8.5 17.5 16.5 7.5 11.5 14.2 8.7 12.7 6.0 9.7 7.6 17.3 14.3 8.4 1.6 10.8 3.8 11.4 9.1 8.0 13.2 4.5 6.0 21.6 9.4 8.8 18.2 12.8 8.4 9.1 8.8 14.4 4.3 3.9 14.3 12.3 4.2 3.9 7.8 5.8 0.2 5.6 3.3 14.3 3.5 11.7 3.8 5.2 12.0 11.3 11.7 7.9 8.3 11.3 7.9 18.9 19.2 4.2 7.8 6.4 5.5 4.3 4.0 2.7 0.1 7.3 0.0 0.2 0.1 0.3 0.3 0.4 0.1 0.4 0.4 0.2 0.2 0.4 0.3 0.1 0.6 0.2 0.4 0.2 0.2 10.7 14.2 14.4 11.5 8.5 11.0 10.5 10.5 9.8 10.2 14.2 13.6 9.4 6.4 11.3 15.7 7.8 2.9 1.8 2.0 2.8 9.0 4.4 2.9 10.3 7.2 1.7 7.3 14.6 1.7 3.4 2.0 1.9 4.7 11.3 9.3 8.2 8.0 3.6 104.0 34.1 2.6 1.9 7.0 1.5 3.7 1.3 6.7 13.2 20.7 3.1 8.4 32.9 2.5 4.1 6.7 2.8 5.8 9.3 4.3 10.6 20.6 10.1 5.5 6.2 36.2 39.4 3.3 1.0 9.8 42.7 2.7 2.0 4.3 8.4 9.2 0.0 14.8 6.0 14.9 6.0 3.7 1.7 1.4 3.7 6.8 2.3 1.2 TBCEL-TECTA ENSG00000285509 "TBCEL-TECTA readthrough" 11 121024125-121113108 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HEL: 1.3" "HPA038593, HPA038594" Uncertain Uncertain Cytosol NA NA "Cluster 36: HEL - Hemostasis" Cytosol "HPA038593: AB_10669647, HPA038594: AB_2676103" 0.1 0.0 0.4 0.1 0.6 0.0 0.1 0.3 0.6 0.2 0.5 0.1 0.1 0.2 0.0 0.1 0.0 0.2 0.2 0.4 1.1 0.3 0.1 0.2 0.0 0.7 0.6 0.2 0.6 0.4 0.2 0.7 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.5 1.1 0.1 0.0 0.0 0.0 0.1 0.6 0.1 0.2 0.5 0.1 0.0 0.1 0.0 0.6 0.7 0.7 0.1 0.3 0.4 0.2 0.2 0.2 0.3 0.0 0.2 0.1 0.7 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.3 0.0 0.3 0.2 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.8 0.2 0.0 0.2 0.7 0.9 0.2 0.0 0.0 0.7 0.4 0.0 0.0 0.6 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.3 0.6 0.4 1.1 0.7 0.6 0.7 0.3 1.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBL2 "DKFZP43N024, WBSCR13, WS-betaTRP" ENSG00000106638 "Transducin beta like 2" Q9Y4P3 7 73567537-73578791 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 44.2" "Group enriched" "Detected in all" 7 "Early spermatids: 398.2;Late spermatids: 515.4;Spermatocytes: 345.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007477, HPA051533" Supported Cytosol "Secreted in male reproductive system" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA007477: AB_1080214, HPA051533: AB_2681523" "unprognostic (9.04e-2)" "unprognostic (6.61e-3)" "unprognostic (4.24e-2)" "unprognostic (1.10e-1)" "unprognostic (1.76e-2)" "prognostic unfavorable (4.93e-4)" "unprognostic (2.24e-3)" "unprognostic (7.50e-2)" "unprognostic (2.87e-1)" "unprognostic (1.90e-1)" "unprognostic (1.74e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (1.88e-5)" "unprognostic (1.59e-1)" "unprognostic (3.14e-1)" "unprognostic (1.42e-2)" "unprognostic (1.31e-1)" 4.9 9.1 1.7 5.3 1.8 1.6 4.2 2.8 5.4 4.6 2.7 4.7 5.4 4.5 8.3 5.4 4.3 2.7 4.0 1.9 1.7 4.2 5.9 5.5 1.9 1.7 1.6 4.8 16.4 5.6 3.2 4.4 1.8 4.4 5.5 4.0 11.0 4.3 2.9 4.9 4.3 4.6 1.6 3.1 6.4 44.2 1.7 2.3 4.9 1.5 3.2 3.6 4.5 1.8 22.1 27.5 8.7 12.6 19.9 18.2 10.2 26.9 18.4 9.3 17.1 40.9 22.0 18.4 5.4 21.7 19.5 15.9 18.2 9.5 19.4 6.8 10.8 6.6 11.8 26.3 28.5 13.3 22.4 11.4 15.0 28.7 22.1 16.7 10.2 2.4 26.0 12.6 14.7 20.2 13.2 10.7 8.7 23.8 18.1 8.6 14.6 38.8 10.5 16.0 8.4 14.3 25.8 65.8 16.9 10.1 17.2 5.7 18.7 17.1 8.8 17.1 25.7 25.8 18.0 20.0 23.3 15.3 21.3 16.8 11.1 4.9 6.3 7.3 5.9 3.0 5.0 5.2 13.6 4.1 5.9 3.7 1.4 8.8 7.4 10.2 6.5 8.1 1.7 1.8 2.8 5.4 1.9 1.7 1.7 1.6 1.8 1.6 1.7 1.8 8.6 25.6 9.3 3.3 8.1 4.6 14.5 17.3 4.0 10.8 10.8 6.3 4.7 11.5 13.5 5.5 8.4 45.2 6.5 12.7 1.9 26.1 398.2 11.3 14.9 12.6 9.5 6.3 4.1 30.1 54.6 17.3 7.7 11.6 14.0 13.9 10.0 14.7 27.4 3.3 4.5 16.8 6.1 9.4 3.8 515.4 23.6 17.5 7.2 4.7 17.3 8.1 10.3 4.5 4.1 22.6 13.7 26.7 19.9 17.1 14.6 5.1 9.8 13.4 6.6 13.8 15.1 345.8 27.9 7.8 3.7 43.4 5.0 17.0 15.8 9.0 TCL1B TML1 ENSG00000213231 "TCL1 family AKT coactivator B" O95988 14 95686426-95692628 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.2;lymphoid tissue: 2.5;testis: 2.5" "Cell type enriched" "Detected in some" 8 "Syncytiotrophoblasts: 72.7" "Cancer enriched" "Detected in single" 72 "testis cancer: 8.3" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 24 "naive B-cell: 11.7;plasmacytoid DC: 6.2" "Group enriched" "Detected in many" 24 "B-cells: 11.7;dendritic cells: 6.2" "Cell line enriched" "Detected in some" 7 "U-698: 511.8" "Not detected" "Not detected" HPA053163 Uncertain Approved Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA053163: AB_2682064" "unprognostic (1.55e-1)" 0.1 0.0 0.1 0.4 0.7 1.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.0 0.0 2.2 0.6 0.4 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.7 0.0 2.5 0.4 0.2 0.0 0.0 2.5 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.1 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 73.5 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.5 0.0 2.5 0.6 0.4 0.0 0.0 1.3 0.0 0.2 0.2 0.4 511.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.3 0.3 0.0 6.2 0.0 0.3 0.1 0.7 0.1 0.2 0.1 0.2 0.6 0.4 0.5 0.1 0.4 1.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.1 9.0 0.0 0.0 72.7 0.0 0.1 0.0 0.1 TCN2 "D22S676, D22S750, TC2" ENSG00000185339 "Transcobalamin 2" P20062 22 30607003-30627271 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cobalt transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 115.8" "Cell type enhanced" "Detected in many" "Adipocytes: 105.0;Hepatic stellate cells: 137.4;Kupffer cells: 144.1;Proximal enterocytes: 563.6;Proximal tubular cells: 125.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 43.8;intermediate monocyte: 66.5;non-classical monocyte: 24.4" "Lineage enriched" "Detected in many" 8 "monocytes: 66.5" "Cell line enhanced" "Detected in many" "ASC TERT1: 117.6;HUVEC TERT2: 142.6;Karpas-707: 184.0;RPTEC TERT1: 70.7;TIME: 85.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000837 Approved Cytosol "Secreted to blood" NA NA 19000000 "Cluster 7: Monocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 45: Enterocytes - Digestion" Cytosol "HPA000837: AB_1080235" "unprognostic (6.43e-2)" "prognostic favorable (3.47e-4)" "unprognostic (1.53e-3)" "unprognostic (3.17e-1)" "unprognostic (1.49e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (2.64e-4)" "unprognostic (1.52e-2)" "unprognostic (2.90e-1)" "unprognostic (1.07e-1)" "unprognostic (4.03e-2)" "unprognostic (1.59e-1)" "unprognostic (6.95e-3)" "unprognostic (4.94e-3)" "unprognostic (2.09e-2)" "unprognostic (1.30e-1)" "unprognostic (1.50e-1)" 49.6 30.6 24.6 16.0 24.1 5.5 37.9 25.5 30.6 25.9 27.1 23.4 23.6 28.7 20.3 8.6 21.5 50.1 28.7 22.7 25.3 115.8 17.3 37.7 35.3 27.1 26.1 14.8 12.1 8.6 15.1 18.6 27.7 16.0 27.8 11.1 13.2 45.4 6.0 9.0 59.5 36.8 25.5 46.7 17.4 21.9 29.7 6.4 26.4 13.7 10.0 22.0 14.7 25.3 0.2 9.5 41.8 0.2 24.6 117.6 1.4 3.1 30.9 8.0 13.1 4.6 21.2 0.6 45.7 6.2 0.7 1.5 3.7 2.2 2.5 0.0 2.3 0.2 1.2 2.0 58.5 0.6 33.7 19.8 2.5 6.1 5.1 8.8 142.6 0.0 0.8 184.0 12.7 0.1 0.1 3.3 16.4 11.7 1.0 4.9 6.0 64.2 70.7 1.1 14.4 1.9 0.3 0.6 12.0 2.8 0.4 2.0 85.3 26.4 3.5 3.3 1.3 5.1 1.4 0.2 9.5 1.7 0.6 0.0 43.8 0.0 0.1 66.5 0.7 0.0 0.8 0.4 7.9 0.0 0.3 0.6 1.4 0.0 24.4 1.5 0.2 18.8 24.6 24.1 25.5 30.6 22.7 25.3 27.1 26.1 27.7 25.5 29.7 25.3 105.0 3.2 3.9 3.9 3.7 5.2 2.2 4.7 0.6 8.0 7.1 5.1 6.5 27.1 13.7 12.9 20.9 0.4 0.5 70.9 7.9 7.8 1.1 3.5 5.4 64.6 6.7 0.8 0.2 6.0 0.8 19.5 5.1 6.2 4.5 23.4 137.4 5.6 45.9 1.7 1.9 28.6 4.1 144.1 9.4 1.4 10.5 53.8 23.2 8.4 8.8 7.4 0.0 5.5 1.7 5.1 50.2 9.8 13.5 2.0 563.6 125.8 2.8 29.1 13.1 0.9 5.5 1.0 12.6 0.5 5.3 0.4 2.2 5.6 21.0 2.7 TCTA ENSG00000145022 "T cell leukemia translocation altered" P57738 3 49412206-49416475 "Disease related genes, Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007342 Approved Approved Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 59: Non-specific - Transcription" Cytosol "HPA007342: AB_2202399" "unprognostic (5.58e-2)" "unprognostic (4.33e-2)" "unprognostic (6.86e-2)" "unprognostic (5.71e-3)" "unprognostic (2.17e-2)" "unprognostic (3.35e-2)" "unprognostic (2.18e-1)" "prognostic favorable (6.76e-4)" "unprognostic (3.74e-1)" "unprognostic (3.38e-3)" "unprognostic (1.82e-3)" "unprognostic (1.03e-1)" "prognostic favorable (5.00e-15)" "unprognostic (1.68e-1)" "unprognostic (1.96e-1)" "unprognostic (3.43e-1)" "unprognostic (6.41e-3)" 21.7 48.0 49.1 13.1 52.3 12.3 21.5 50.1 52.9 23.2 47.0 24.7 18.9 23.1 60.6 15.6 26.1 16.6 22.6 48.4 50.6 51.0 41.9 23.5 15.8 51.6 51.6 27.1 24.1 39.8 48.8 14.5 52.3 34.5 28.8 14.0 21.8 25.1 19.6 14.2 23.1 21.8 48.8 25.9 23.3 15.7 52.1 20.1 45.3 13.8 16.0 25.4 15.9 51.5 12.8 15.5 9.8 14.8 42.5 18.5 12.9 26.0 19.2 25.8 21.6 9.1 13.6 15.2 18.6 61.5 29.6 14.4 19.3 26.2 21.0 22.9 13.4 25.4 19.6 11.9 25.8 10.9 31.9 40.2 26.8 28.7 22.9 24.7 27.0 12.0 9.4 33.8 63.8 11.7 13.4 9.8 8.0 24.1 35.5 8.1 10.6 36.0 44.5 16.7 26.3 8.7 30.9 33.8 28.6 19.7 28.8 10.2 24.5 19.3 11.9 40.4 9.8 18.4 26.1 10.4 45.4 19.3 27.2 20.4 17.8 23.2 19.1 34.2 11.1 12.0 12.0 14.7 10.1 13.7 14.9 15.5 20.1 23.0 47.5 15.6 17.8 22.4 49.1 52.3 50.1 52.9 48.4 50.6 51.6 51.6 52.3 48.8 52.1 51.5 15.5 25.6 15.6 8.8 19.3 2.7 10.0 10.3 14.2 10.2 19.9 18.0 14.1 20.0 12.9 27.6 12.5 25.9 20.5 34.0 46.9 15.3 8.0 15.5 15.0 14.7 17.5 9.0 12.3 11.6 11.5 17.6 53.5 17.0 5.7 7.1 11.4 31.8 24.8 10.1 11.0 19.1 20.3 18.6 6.0 14.3 15.5 19.2 14.2 11.2 15.5 26.3 26.8 11.1 16.8 15.1 28.6 16.1 13.2 13.4 34.9 50.3 22.8 11.3 6.6 13.7 16.6 8.2 6.1 10.4 4.5 20.0 21.6 22.1 16.6 7.9 TENT2 "FLJ38499, GLD2, PAPD4, TUT2" ENSG00000164329 "Terminal nucleotidyltransferase 2" Q6PIY7 5 79612120-79686648 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "mRNA processing" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 37.6;Glandular and luminal cells: 33.2;Granulosa cells: 31.9;Hofbauer cells: 33.9;Syncytiotrophoblasts: 33.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054468 Approved Cytosol No No "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA054468: AB_2682497" "unprognostic (1.52e-1)" "unprognostic (2.17e-1)" "unprognostic (6.25e-3)" "unprognostic (1.91e-1)" "unprognostic (8.03e-2)" "unprognostic (2.80e-3)" "unprognostic (2.10e-2)" "unprognostic (1.10e-1)" "unprognostic (6.80e-2)" "unprognostic (1.57e-3)" "unprognostic (9.37e-2)" "unprognostic (2.21e-1)" "unprognostic (7.71e-2)" "unprognostic (2.38e-1)" "unprognostic (8.43e-3)" "unprognostic (5.84e-3)" "unprognostic (2.67e-3)" 19.1 15.1 10.4 20.4 12.8 44.4 25.0 11.5 15.6 17.9 15.0 18.5 17.8 19.6 23.6 16.5 16.0 17.3 14.5 9.6 10.8 17.6 23.8 17.9 30.2 12.0 11.1 22.7 15.2 15.5 11.5 21.0 12.5 15.7 20.8 14.3 15.1 15.3 16.2 23.8 19.1 18.3 10.9 27.8 17.7 17.5 11.2 27.2 22.4 14.3 28.1 19.1 15.9 15.2 22.5 15.3 16.8 26.7 28.8 33.2 26.8 26.6 40.6 30.5 48.3 13.8 26.1 41.8 13.6 29.6 35.9 21.1 21.8 29.6 34.6 31.3 19.9 23.9 19.4 21.6 37.3 35.7 31.6 29.5 31.4 21.6 40.1 29.7 26.2 30.0 27.7 30.0 34.0 12.3 40.8 45.6 15.6 17.0 10.8 36.2 16.8 47.2 29.4 31.8 11.0 20.1 21.1 22.8 42.8 26.4 19.6 55.6 24.2 16.4 11.1 16.0 29.9 31.3 27.8 40.7 28.9 36.8 23.4 30.7 21.5 21.6 19.0 24.8 31.3 21.6 20.5 21.0 21.9 17.2 19.5 20.6 19.2 21.8 26.0 12.0 23.4 19.0 10.4 12.8 11.5 15.6 9.6 10.8 12.0 11.1 12.5 10.9 11.2 15.2 25.9 0.0 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.0 24.2 16.5 0.0 0.0 0.0 27.6 0.0 26.3 37.6 0.0 17.6 10.2 0.0 21.3 29.0 7.2 0.0 0.0 0.0 10.2 22.6 8.7 0.0 33.2 0.0 31.9 0.0 0.0 33.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 9.8 0.0 0.0 0.0 0.0 14.9 0.0 0.0 11.5 0.0 0.0 26.5 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 33.7 11.0 23.7 0.0 0.0 TESPA1 "ITPRID3, KIAA0748" ENSG00000135426 "Thymocyte expressed, positive selection associated 1" A2RU30 12 54948015-54984762 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 81.3;lymphoid tissue: 75.2" "Group enriched" "Detected in some" 4 "Excitatory neurons: 202.7;granulocytes: 120.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "HEL: 247.1;HMC-1: 187.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA058823, HPA079222" Approved Supported Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA058823: AB_2683828, HPA079222: " "unprognostic (1.98e-5)" "unprognostic (3.70e-4)" "unprognostic (3.87e-4)" "unprognostic (1.13e-3)" "unprognostic (3.20e-2)" "unprognostic (4.55e-4)" "unprognostic (2.29e-3)" "unprognostic (5.34e-4)" "unprognostic (3.83e-4)" "unprognostic (1.35e-2)" "unprognostic (3.97e-2)" "unprognostic (5.89e-2)" "unprognostic (4.50e-2)" "unprognostic (4.11e-1)" "unprognostic (1.28e-2)" "unprognostic (1.25e-1)" "unprognostic (1.71e-1)" 1.3 0.5 19.6 13.9 37.6 14.5 1.7 12.0 81.3 1.9 11.9 3.7 3.0 2.3 4.8 1.9 1.3 4.8 1.0 36.6 13.2 0.8 0.9 5.8 36.4 11.6 12.2 6.9 0.9 0.7 0.6 0.5 12.1 1.5 4.8 1.0 1.4 1.1 1.4 1.0 7.5 2.1 11.4 13.5 3.9 0.9 16.1 75.2 1.1 0.6 36.4 4.0 1.1 44.2 0.2 0.4 0.6 0.4 0.7 0.7 3.2 0.0 0.7 0.2 0.3 0.0 0.4 17.5 0.2 0.7 0.6 0.4 0.7 0.4 0.3 20.0 0.6 247.1 0.8 0.3 0.6 13.6 187.7 0.5 0.4 0.4 0.7 0.5 0.0 41.5 1.0 16.3 0.4 0.4 39.1 1.5 0.5 0.2 0.2 9.3 0.3 2.7 0.6 0.9 0.5 0.2 0.6 0.1 0.5 0.7 0.2 3.6 0.3 0.4 0.4 0.2 0.2 11.1 0.4 12.0 1.7 4.0 0.4 43.1 1.4 1.6 38.3 1.3 43.5 17.9 126.0 57.5 16.0 15.0 175.8 98.8 3.1 57.2 1.5 5.6 92.6 64.5 19.6 37.6 12.0 81.3 36.6 13.2 11.6 12.2 12.1 11.4 16.1 44.2 0.7 0.0 4.3 10.1 9.9 0.5 0.0 0.0 0.0 0.0 0.2 0.3 1.5 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.0 32.4 202.7 0.0 0.0 1.3 0.0 0.1 120.1 0.0 0.4 0.5 0.1 0.0 2.5 0.0 0.0 1.3 1.6 0.0 0.9 4.6 1.8 2.8 3.3 0.0 25.7 7.1 5.1 0.0 0.0 1.2 3.4 0.0 0.0 0.3 0.0 0.0 0.0 0.3 1.0 0.0 0.2 0.0 0.3 0.0 37.0 0.8 0.1 0.0 TEX37 "C2orf51, FLJ25369, TSC21" ENSG00000172073 "Testis expressed 37" Q96LM6 2 88524649-88529585 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 640 "testis: 85.0" "Group enriched" "Detected in some" 229 "Early spermatids: 846.6;Late spermatids: 3191.0" "Cancer enriched" "Detected in single" 17 "testis cancer: 2.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 31 "BEWO: 50.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA043987, HPA070239" Enhanced Supported Cytosol NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA043987: AB_10961125, HPA070239: " "unprognostic (1.08e-3)" "unprognostic (2.24e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 85.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 50.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 846.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3191.0 8.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 8.4 8.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 TFEB "bHLHe35, TCFEB" ENSG00000112561 "Transcription factor EB" P19484 6 41683978-41736259 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Autophagy, Immunity, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 89.9" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 97.4;Syncytiotrophoblasts: 120.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 16.1;eosinophil: 16.9;intermediate monocyte: 16.3;memory B-cell: 34.2;myeloid DC: 14.7;naive B-cell: 22.6;neutrophil: 47.4;non-classical monocyte: 14.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 60.3;Daudi: 35.8;OE19: 53.1;U-698: 42.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067082 Supported Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 57: B-cells - Immune response" Cytosol "HPA067082: " "unprognostic (3.63e-3)" "unprognostic (1.51e-3)" "unprognostic (1.75e-2)" "unprognostic (4.48e-3)" "unprognostic (1.95e-1)" "unprognostic (1.05e-1)" "unprognostic (1.64e-1)" "unprognostic (4.22e-3)" "unprognostic (1.39e-2)" "unprognostic (4.13e-2)" "prognostic favorable (4.77e-4)" "unprognostic (2.12e-2)" "prognostic favorable (1.06e-5)" "unprognostic (1.44e-1)" "unprognostic (3.51e-2)" "unprognostic (2.46e-1)" "unprognostic (1.31e-2)" 14.3 10.7 18.3 16.7 29.9 8.3 15.0 24.0 23.5 13.4 9.6 25.7 5.8 11.1 1.5 14.8 12.8 7.7 37.1 18.1 19.7 26.7 11.6 18.2 26.1 30.9 27.7 6.5 12.9 17.8 31.3 14.5 25.8 23.4 4.3 2.2 21.2 7.0 89.9 17.9 34.6 5.7 22.5 57.2 14.4 2.6 25.4 5.0 22.9 41.5 17.2 19.6 15.6 39.9 3.5 3.2 0.6 12.3 3.8 2.5 60.3 5.3 6.9 3.4 2.7 6.9 2.7 35.8 6.8 3.5 2.9 8.7 2.4 4.9 1.0 28.3 4.1 0.1 8.8 12.8 6.8 1.0 4.3 0.7 9.8 4.9 2.6 6.9 4.1 3.3 4.1 7.4 1.0 1.8 2.3 1.2 0.1 53.1 1.6 24.3 0.1 5.0 7.5 2.6 12.8 4.3 4.7 10.5 1.0 3.4 2.3 19.5 7.1 1.5 3.1 0.1 3.0 15.7 2.3 42.1 2.6 15.3 0.9 0.3 16.1 16.9 3.8 16.3 0.9 34.2 1.5 1.8 14.7 22.6 0.4 1.5 47.4 1.7 14.1 2.9 0.6 8.7 18.3 29.9 24.0 23.5 18.1 19.7 30.9 27.7 25.8 22.5 25.4 39.9 14.5 9.6 9.3 10.1 36.7 14.1 8.2 14.8 5.2 6.1 5.7 5.6 19.2 10.0 6.0 12.9 12.5 50.7 13.8 16.3 21.5 3.7 1.1 11.4 2.6 12.2 13.2 3.2 6.3 6.9 8.3 6.9 6.1 8.0 1.3 0.5 6.4 4.2 26.8 26.9 7.9 10.2 26.4 22.8 13.3 4.2 3.4 19.6 0.0 17.8 20.0 18.4 22.6 11.1 97.4 10.6 18.0 10.9 16.0 7.1 14.1 3.7 7.4 5.2 6.6 13.1 7.8 0.9 1.0 6.4 14.5 120.4 9.1 0.8 8.8 6.3 TGFBR3 "betaglycan, BGCAN" ENSG00000069702 "Transforming growth factor beta receptor 3" Q03167 1 91680343-91906335 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 143.9;Hepatic stellate cells: 322.7;Leydig cells: 146.3;Skeletal myocytes: 187.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 35.2" "Group enriched" "Detected in many" 18 "NK-cells: 16.6;T-cells: 35.2" "Cell line enhanced" "Detected in many" "ASC diff: 227.2;ASC TERT1: 108.4;RT4: 57.1;U-2197: 78.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008257, CAB018971" Supported Approved Cytosol "Secreted to blood" NA NA 50000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "CAB018971: , HPA008257: AB_1080258" "unprognostic (7.57e-2)" "unprognostic (3.67e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (3.36e-4)" "unprognostic (9.39e-3)" "prognostic favorable (4.84e-4)" "unprognostic (2.07e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-1)" "unprognostic (1.79e-1)" "unprognostic (9.32e-2)" "unprognostic (1.07e-1)" "prognostic favorable (4.99e-4)" "unprognostic (2.46e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (3.14e-4)" "unprognostic (1.08e-2)" 66.3 35.2 6.9 9.2 6.8 5.0 62.1 7.6 8.0 56.6 20.4 28.8 8.2 33.9 24.2 28.5 36.6 20.0 16.2 7.6 6.7 28.2 16.6 27.3 7.2 6.0 10.1 81.5 12.3 5.9 7.1 58.5 7.8 16.4 12.5 1.5 35.0 32.7 12.8 25.0 19.7 27.4 7.9 40.0 18.1 11.0 8.0 7.7 13.2 29.4 4.2 47.3 28.6 7.8 9.9 9.4 14.1 2.4 227.2 108.4 44.6 7.1 35.3 8.1 9.9 4.4 1.4 0.1 1.7 13.0 6.4 1.4 3.6 1.0 6.2 34.1 7.6 0.0 11.1 41.2 5.0 0.3 0.1 26.3 4.7 17.8 4.0 1.3 4.2 0.0 23.6 0.7 2.4 0.2 0.1 0.1 5.9 4.6 3.2 0.5 4.8 2.1 3.2 57.1 0.7 0.0 3.4 0.2 20.4 5.8 1.2 3.7 12.7 13.5 3.5 78.0 1.7 34.8 3.3 0.0 2.8 1.9 1.7 1.2 0.0 0.0 35.2 0.2 19.4 0.0 8.7 19.2 0.0 0.0 2.7 12.7 0.6 16.6 1.4 1.2 4.5 8.1 6.9 6.8 7.6 8.0 7.6 6.7 6.0 10.1 7.8 7.9 8.0 7.8 77.6 9.6 9.7 58.8 3.1 37.6 10.0 2.3 44.3 0.3 38.2 60.1 20.7 30.0 4.2 31.3 2.1 27.5 66.7 0.5 3.9 2.0 54.3 11.2 32.8 90.5 24.0 10.7 7.7 5.1 12.0 143.9 5.1 8.1 2.5 20.5 322.7 21.0 11.8 0.0 34.0 1.9 8.2 23.2 29.4 29.8 146.3 5.2 35.6 82.4 0.7 1.2 62.8 7.5 0.9 3.3 0.4 74.4 21.3 8.5 1.4 20.9 8.3 0.2 13.1 187.2 36.5 0.8 2.2 17.2 34.1 58.0 36.9 92.2 3.7 8.0 TGS1 "NCOA6IP, PIMT" ENSG00000137574 "Trimethylguanosine synthase 1" Q96RS0 8 55773446-55826445 "Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025024, HPA029824" Supported Supported Cytosol NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Cytosol "HPA025024: AB_1854330, HPA029824: AB_2673212" "unprognostic (4.13e-2)" "unprognostic (7.46e-2)" "unprognostic (6.64e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (2.11e-1)" "unprognostic (2.47e-1)" "unprognostic (3.70e-2)" "unprognostic (1.60e-2)" "unprognostic (4.94e-2)" "unprognostic (9.32e-2)" "unprognostic (3.15e-2)" "unprognostic (3.58e-1)" "unprognostic (2.22e-2)" "unprognostic (8.62e-2)" "unprognostic (7.23e-2)" "unprognostic (3.42e-1)" "unprognostic (2.85e-2)" 5.9 4.0 1.8 5.0 1.4 7.2 5.5 3.8 2.3 5.0 2.5 4.9 3.1 5.9 4.1 5.7 5.8 4.1 3.5 1.5 1.5 5.5 4.0 4.5 8.5 1.2 1.3 6.0 4.0 6.8 4.0 4.2 1.3 4.5 4.6 2.5 4.9 5.7 7.4 6.4 5.5 4.6 1.1 5.7 4.5 4.9 1.6 9.5 5.4 2.6 8.5 7.3 5.1 1.9 12.0 9.0 10.2 12.7 9.7 8.2 10.3 10.9 11.6 11.9 12.3 8.5 10.7 27.7 7.0 8.5 8.5 10.8 24.3 14.7 16.3 17.2 8.7 31.6 10.6 5.1 13.1 16.8 9.4 9.7 10.1 11.4 22.7 5.2 9.5 16.0 24.8 9.9 9.6 9.4 36.0 10.6 35.0 16.8 3.6 26.4 7.1 8.2 10.6 12.0 10.6 13.3 19.4 8.0 10.4 10.5 10.9 9.7 9.7 8.4 10.6 9.8 10.4 8.5 6.3 32.1 8.5 13.6 11.3 5.0 2.7 4.3 5.1 2.8 6.0 4.6 4.8 4.7 2.4 4.8 5.2 5.2 3.4 3.3 3.9 5.2 4.2 2.6 1.8 1.4 3.8 2.3 1.5 1.5 1.2 1.3 1.3 1.1 1.6 1.9 29.8 48.1 35.2 15.7 41.6 37.0 36.8 25.7 35.3 30.6 21.8 34.7 15.5 20.0 37.9 51.5 22.9 29.6 30.4 10.8 3.9 20.3 3.7 28.2 42.6 27.2 10.7 49.2 28.9 25.2 26.7 32.4 23.4 27.6 50.0 24.3 20.7 17.2 20.3 21.9 30.0 23.3 16.2 16.8 12.2 4.6 29.5 22.2 7.2 12.2 26.1 27.7 29.9 34.7 19.9 22.2 12.1 23.0 32.7 42.3 10.9 17.7 25.5 29.5 26.3 40.5 25.7 88.2 78.3 33.5 26.1 22.4 41.2 35.2 22.5 31.9 TH DYT5b ENSG00000180176 "Tyrosine hydroxylase" P07101 11 2163929-2171815 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Catecholamine biosynthesis, Neurotransmitter biosynthesis" "Monooxygenase, Oxidoreductase" "Disease variant, Dystonia, FDA approved drug targets, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 69 "adrenal gland: 196.6;brain: 270.9" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 9.0;Extravillous trophoblasts: 12.4;Leydig cells: 3.4;Syncytiotrophoblasts: 2.2" "Cancer enriched" "Detected in some" 5 "urothelial cancer: 4.0" "Group enriched" "Detected in many" 5 "midbrain: 192.4;pons: 270.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 30 "PC-3: 60.8;SK-BR-3: 21.0" "Region enhanced" "Detected in many" "olfactory bulb: 178.8" "Region enriched" "Detected in many" 20 "midbrain: 594.4" "CAB002522, HPA013768, HPA014010, HPA061003, CAB072340" Enhanced Supported Approved Cytosol NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "CAB002522: AB_564047, CAB072340: , HPA013768: , HPA014010: , HPA061003: AB_2630374" "unprognostic (1.31e-1)" "unprognostic (1.30e-1)" "unprognostic (9.08e-2)" "unprognostic (1.75e-4)" "unprognostic (8.82e-3)" "unprognostic (5.88e-2)" "unprognostic (1.93e-1)" "unprognostic (1.74e-3)" "unprognostic (3.83e-2)" "unprognostic (4.39e-4)" "unprognostic (4.97e-1)" "unprognostic (3.61e-2)" "unprognostic (1.92e-1)" "unprognostic (1.60e-1)" "unprognostic (2.43e-1)" "unprognostic (2.70e-2)" "unprognostic (2.18e-2)" 3.3 196.6 1.9 0.1 3.0 0.0 0.0 0.2 1.3 0.6 0.2 0.1 0.0 0.5 0.1 0.7 0.2 0.4 0.1 1.3 46.5 0.4 0.4 0.0 0.0 13.9 192.4 0.7 0.2 0.0 1.7 0.1 270.9 0.3 0.0 0.1 0.1 0.0 0.0 0.8 0.5 0.0 0.8 0.2 0.3 0.5 14.6 0.0 0.0 0.0 0.0 1.4 1.5 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.6 60.8 0.0 0.0 0.0 0.1 0.1 1.1 0.2 0.0 21.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 3.0 0.2 1.3 1.3 46.5 13.9 192.4 270.9 0.8 14.6 1.6 0.3 0.0 0.0 0.0 0.5 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.9 0.0 0.2 1.8 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.4 9.0 0.4 0.0 0.0 0.1 0.0 12.4 0.4 0.0 0.3 0.0 0.0 1.1 0.2 0.5 0.0 0.3 0.1 0.0 0.0 0.3 0.2 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.0 2.2 0.1 0.3 0.2 0.2 THADA "ARMC13, FLJ21877, GITA, KIAA1767" ENSG00000115970 "THADA armadillo repeat containing" Q6YHU6 2 43230851-43596038 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 74.7;Excitatory neurons: 77.5;Inhibitory neurons: 77.2;Microglial cells: 89.9;Oligodendrocyte precursor cells: 73.9;Oligodendrocytes: 111.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 17.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035191, HPA035192" Uncertain Approved Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA035191: AB_10670290, HPA035192: AB_2674512" "unprognostic (1.20e-1)" "unprognostic (2.95e-1)" "unprognostic (2.07e-1)" "unprognostic (1.61e-1)" "unprognostic (1.13e-1)" "unprognostic (4.26e-1)" "prognostic unfavorable (6.48e-4)" "unprognostic (8.27e-2)" "unprognostic (9.63e-2)" "unprognostic (1.36e-1)" "unprognostic (1.66e-1)" "unprognostic (2.13e-1)" "unprognostic (4.38e-2)" "unprognostic (1.12e-1)" "unprognostic (3.43e-2)" "unprognostic (5.25e-2)" "unprognostic (2.14e-1)" 11.0 9.3 7.0 7.5 8.3 8.9 11.1 7.1 7.3 12.1 14.8 9.1 4.2 11.0 10.2 9.9 11.1 6.1 9.0 6.9 7.3 9.6 17.3 9.8 14.3 8.3 8.2 11.5 11.5 12.4 11.1 6.1 7.9 13.0 6.1 8.3 10.2 6.9 10.1 13.8 9.4 7.3 7.3 11.7 9.1 10.2 8.1 10.2 13.5 6.1 9.8 10.5 11.0 9.3 19.2 22.6 10.0 0.3 26.6 22.8 14.4 12.6 10.3 11.6 9.8 13.3 11.3 17.5 21.0 15.0 15.8 17.4 15.7 21.6 19.9 14.6 15.5 12.5 8.6 17.7 9.3 19.5 9.7 15.0 19.1 24.5 31.8 12.2 16.1 6.5 22.6 9.1 14.2 24.2 19.4 21.7 20.2 27.4 12.7 8.9 18.1 13.3 18.4 16.9 13.2 20.5 11.9 11.5 11.3 11.6 11.8 10.1 13.6 19.0 14.0 14.7 22.9 23.0 15.2 19.6 15.4 19.1 15.7 17.2 2.6 1.2 3.4 4.0 3.7 3.6 3.7 4.2 4.2 3.6 3.4 4.0 1.8 5.4 2.9 3.2 4.5 2.2 7.0 8.3 7.1 7.3 6.9 7.3 8.3 8.2 7.9 7.3 8.1 9.3 11.7 19.2 14.4 74.7 15.4 8.5 16.5 8.9 23.3 11.9 11.8 11.0 8.5 18.6 12.0 14.7 16.7 7.9 9.6 5.1 1.9 8.8 20.9 19.5 17.0 10.3 7.3 12.4 77.5 9.6 5.4 12.5 15.3 11.2 6.3 19.7 11.4 17.8 9.7 3.3 77.2 5.4 4.1 9.7 7.4 11.1 9.9 12.9 3.6 89.9 7.9 5.3 10.3 73.9 111.0 6.4 7.2 8.6 11.5 11.3 2.5 7.4 22.6 24.9 0.0 16.2 9.1 20.7 14.1 11.0 4.4 4.8 16.5 20.3 6.3 7.4 THAP12 "DAP4, P52rIPK, PRKRIR, THAP0" ENSG00000137492 "THAP domain containing 12" O43422 11 76349956-76381132 "Plasma proteins, Predicted membrane proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 42.4;dendritic cells: 31.6;Endometrial stromal cells: 34.7;Theca cells: 34.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 241.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008758, HPA077077" Approved Approved Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA008758: AB_1855714, HPA077077: " "unprognostic (2.79e-1)" "unprognostic (9.79e-2)" "unprognostic (1.16e-3)" "unprognostic (6.47e-2)" "unprognostic (8.85e-3)" "unprognostic (1.23e-1)" "unprognostic (4.03e-3)" "unprognostic (1.08e-1)" "unprognostic (6.68e-3)" "unprognostic (1.48e-1)" "unprognostic (1.57e-2)" "unprognostic (2.65e-2)" "unprognostic (7.98e-2)" "unprognostic (2.06e-1)" "unprognostic (3.95e-2)" "unprognostic (1.54e-1)" "unprognostic (4.79e-2)" 25.7 21.9 13.8 20.1 14.2 33.4 29.7 13.6 16.3 21.4 13.2 24.1 19.9 24.2 21.1 11.2 19.0 16.7 17.2 14.4 13.8 19.6 19.5 21.8 33.0 13.1 14.2 20.3 41.6 14.2 9.5 26.2 13.1 17.1 25.7 37.2 15.6 19.0 31.7 14.5 20.0 22.0 13.9 26.0 21.5 18.1 14.2 30.6 22.1 32.9 28.7 20.4 15.0 13.6 37.7 29.3 54.6 31.1 36.4 51.5 33.4 38.0 38.9 46.4 40.8 58.9 38.9 100.8 57.1 36.2 40.7 36.5 67.4 44.6 73.9 78.3 21.5 72.2 20.2 27.4 40.2 92.3 34.9 37.1 57.8 41.3 76.9 28.1 40.7 70.5 85.3 55.3 42.0 40.4 81.4 51.9 22.7 98.5 31.8 60.3 124.7 105.0 27.1 38.8 53.1 35.6 36.7 40.1 20.5 36.5 40.6 35.8 36.7 55.4 91.7 114.2 33.9 49.9 56.6 241.7 13.3 50.8 30.6 0.7 1.5 1.7 4.5 1.6 5.2 3.3 4.7 5.0 2.1 3.6 3.4 4.4 0.5 5.6 1.5 0.9 4.7 1.7 13.8 14.2 13.6 16.3 14.4 13.8 13.1 14.2 13.1 13.9 14.2 13.6 42.4 25.6 25.3 0.0 13.6 0.0 0.0 0.0 0.0 0.0 29.6 24.0 0.0 0.0 6.2 11.0 0.0 14.2 31.6 0.0 13.7 10.9 0.0 13.6 34.7 9.8 0.0 0.0 0.0 26.4 21.5 11.3 0.0 19.3 7.6 24.5 0.0 0.0 20.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 8.3 0.0 0.0 0.0 0.0 14.1 0.0 0.0 7.6 0.0 0.0 16.3 5.8 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 16.3 13.4 34.4 0.0 0.0 THOP1 ENSG00000172009 "Thimet oligopeptidase 1" P52888 19 2785503-2815807 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 136.6;Paneth cells: 160.6;Proximal enterocytes: 312.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025497, HPA035262" Uncertain Supported Cytosol NA NA 2000000 "Cluster 18: Basophils - Vesicular transport" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 45: Enterocytes - Digestion" Cytosol "CAB025497: , HPA035262: AB_2674541" "unprognostic (1.52e-2)" "unprognostic (1.73e-3)" "unprognostic (7.94e-2)" "prognostic favorable (2.35e-4)" "unprognostic (1.82e-1)" "unprognostic (2.16e-2)" "unprognostic (9.35e-2)" "unprognostic (1.19e-1)" "unprognostic (4.05e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-3)" "unprognostic (3.00e-2)" "unprognostic (1.39e-1)" "prognostic favorable (5.90e-4)" "unprognostic (1.27e-1)" "unprognostic (2.64e-1)" "unprognostic (5.37e-2)" 13.4 19.6 31.8 11.8 31.6 19.6 15.3 29.8 48.4 15.3 25.4 21.3 22.6 18.7 6.3 31.0 17.6 3.3 38.0 33.2 28.7 22.7 73.0 13.7 11.6 33.7 31.7 18.8 17.5 6.0 32.0 7.8 30.7 37.6 7.0 9.3 15.7 5.2 40.6 20.0 21.5 6.1 26.9 23.0 16.1 70.2 28.6 13.8 17.9 11.0 8.3 18.7 15.9 30.4 91.4 66.3 25.1 54.6 12.8 12.5 89.9 55.4 20.4 53.8 43.4 78.4 28.3 81.3 26.4 21.7 37.7 72.4 37.8 45.6 22.5 0.3 79.7 28.9 75.9 94.4 13.7 56.3 43.1 13.9 16.0 44.8 20.0 15.5 31.0 54.0 68.2 38.7 23.1 70.5 63.1 105.0 74.7 27.2 90.2 51.7 33.8 77.5 22.8 51.9 68.5 54.6 48.5 42.9 27.6 13.1 41.8 53.8 35.5 41.2 35.5 88.6 95.4 67.1 60.7 55.7 46.0 93.3 50.1 9.3 2.5 1.2 3.7 2.9 3.0 3.8 2.7 5.2 3.6 5.3 3.4 3.0 1.0 3.0 6.0 7.0 7.6 2.5 31.8 31.6 29.8 48.4 33.2 28.7 33.7 31.7 30.7 26.9 28.6 30.4 5.1 3.2 10.6 15.0 12.0 6.8 10.3 15.6 11.4 20.3 12.6 10.8 9.0 5.7 9.7 11.0 35.5 27.6 8.7 136.6 9.8 18.7 17.6 11.1 8.3 7.4 40.8 13.7 12.1 15.1 55.9 11.1 9.2 10.1 5.7 23.1 7.1 85.9 23.0 6.7 10.5 59.9 6.1 9.8 6.0 23.4 11.5 9.1 3.6 3.7 8.3 13.5 4.1 4.0 7.1 21.3 160.6 6.0 17.2 16.6 312.2 10.8 9.7 32.4 13.1 10.6 15.0 55.6 19.2 13.4 5.8 33.8 8.0 15.9 48.2 8.4 THRA "AR7, EAR-7.1/EAR-7.2, ERBA, ERBA1, NR1A1, THRA1, THRA2, THRA3" ENSG00000126351 "Thyroid hormone receptor alpha" P10827 17 40058290-40093867 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 236.7" "Cell type enhanced" "Detected in many" "Muller glia cells: 95.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009654, CAB023349" Approved Supported Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "CAB023349: AB_619577, HPA009654: AB_1854603" "unprognostic (2.75e-2)" "unprognostic (2.20e-1)" "unprognostic (6.64e-2)" "unprognostic (4.22e-2)" "unprognostic (8.78e-2)" "unprognostic (1.64e-1)" "unprognostic (3.41e-3)" "prognostic favorable (1.84e-4)" "unprognostic (1.47e-1)" "unprognostic (5.47e-2)" "unprognostic (7.85e-2)" "unprognostic (2.65e-2)" "prognostic favorable (6.05e-8)" "unprognostic (3.05e-1)" "unprognostic (1.35e-1)" "unprognostic (4.21e-1)" "unprognostic (1.88e-3)" 40.7 43.7 199.1 12.0 236.7 23.0 38.9 159.3 218.3 67.5 108.5 67.2 31.1 49.9 22.0 19.1 57.7 25.8 63.8 189.7 181.8 34.1 10.2 32.2 9.7 162.4 172.1 90.7 31.3 29.9 50.0 17.1 149.4 34.5 18.8 35.4 27.3 35.5 90.7 50.2 36.2 34.6 166.5 13.9 48.0 18.7 183.6 12.8 32.6 52.8 6.3 45.0 45.9 179.9 4.9 37.6 11.5 28.9 77.4 28.2 4.2 19.3 23.0 19.6 18.2 31.5 27.2 5.6 31.3 37.6 8.7 11.4 22.6 11.7 10.6 2.1 21.6 10.4 44.5 13.4 26.0 16.9 11.2 45.1 9.5 18.4 7.1 45.4 26.6 16.7 21.2 5.2 16.5 7.1 22.8 27.4 10.6 24.6 11.8 32.1 22.7 27.6 6.4 3.3 19.5 17.7 14.8 23.3 33.7 17.5 27.3 19.5 18.7 19.4 18.9 17.7 5.9 11.9 9.0 3.4 12.0 19.1 10.6 0.2 0.3 1.9 2.0 0.1 0.8 0.2 0.8 1.2 0.3 0.4 1.4 1.7 1.1 2.1 0.3 0.6 1.0 0.7 199.1 236.7 159.3 218.3 189.7 181.8 162.4 172.1 149.4 166.5 183.6 179.9 32.2 19.2 7.3 27.1 6.2 10.6 28.1 3.3 31.3 76.4 19.6 21.2 45.4 38.6 2.7 33.1 20.9 0.8 16.5 37.9 50.9 12.3 1.1 20.5 29.5 20.8 25.1 17.9 19.1 14.8 1.4 36.8 29.0 12.1 14.0 23.1 24.7 13.8 11.6 62.2 24.2 22.6 6.1 10.6 5.1 2.7 51.6 8.6 19.6 8.4 5.1 95.2 37.0 15.6 26.5 6.9 14.6 49.7 3.9 17.2 58.8 29.9 7.5 22.5 19.7 84.7 44.4 0.3 27.3 14.6 10.4 0.3 18.1 16.3 39.9 13.8 THSD1 TMTSP ENSG00000136114 "Thrombospondin type 1 domain containing 1" Q9NS62 13 52377167-52416373 "Disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 22.0;Astrocytes: 25.5;Basal respiratory cells: 16.5;Endothelial cells: 29.9;Hepatic stellate cells: 17.2;Microglial cells: 17.8;Spermatocytes: 18.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 19.9;HBEC3-KT: 19.9;hTCEpi: 19.0;hTERT-HME1: 19.5;HUVEC TERT2: 40.6;LHCN-M2: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012611, CAB020796" Uncertain Supported Cytosol "Intracellular and membrane" No No 1400000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB020796: , HPA012611: AB_1857990" "unprognostic (1.21e-1)" "unprognostic (7.54e-3)" "unprognostic (3.49e-2)" "unprognostic (6.39e-2)" "unprognostic (1.31e-1)" "unprognostic (1.54e-2)" "unprognostic (1.13e-1)" "unprognostic (1.05e-1)" "unprognostic (8.87e-2)" "unprognostic (3.35e-1)" "unprognostic (6.10e-3)" "unprognostic (1.55e-1)" "unprognostic (3.05e-3)" "unprognostic (8.44e-2)" "unprognostic (1.31e-1)" "unprognostic (3.35e-2)" "unprognostic (4.90e-2)" 10.0 2.0 7.9 1.0 7.4 0.2 8.7 5.5 8.5 5.3 4.5 2.8 0.7 5.2 2.8 3.1 5.1 3.3 9.0 8.2 5.5 3.0 2.2 11.5 2.1 6.0 5.4 2.1 1.4 1.4 3.4 11.3 5.8 4.1 1.4 6.8 3.9 1.9 4.5 6.3 2.7 4.7 5.6 5.9 2.1 2.1 6.4 1.4 5.0 10.4 1.6 3.8 4.5 5.9 0.9 3.9 0.5 3.5 3.1 10.3 0.8 8.4 4.1 3.2 5.1 0.1 0.7 0.3 1.0 19.9 3.1 4.4 0.0 19.9 4.9 9.3 2.9 0.5 0.0 0.0 1.9 2.1 0.6 4.1 19.0 15.4 19.5 1.8 40.6 1.2 0.0 0.3 18.6 0.0 0.7 0.4 0.3 0.2 0.9 0.6 4.3 0.0 4.5 0.2 0.1 0.7 0.2 0.1 0.8 0.2 0.4 0.3 9.6 1.0 1.7 0.0 6.3 0.6 0.1 0.1 1.8 0.6 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 7.4 5.5 8.5 8.2 5.5 6.0 5.4 5.8 5.6 6.4 5.9 22.0 0.0 1.1 25.5 0.9 1.5 1.1 16.5 0.6 8.0 1.5 3.0 3.1 0.0 1.8 1.8 2.1 5.4 3.6 0.3 3.9 0.3 1.4 0.8 1.0 29.9 0.0 0.0 3.5 0.6 1.8 6.4 1.1 0.7 0.0 1.5 17.2 2.0 3.1 0.0 3.1 0.3 0.0 1.6 1.6 0.6 3.4 0.6 5.4 17.8 0.4 1.2 1.0 3.0 0.9 0.4 0.2 3.8 0.6 1.8 0.4 0.8 1.3 3.2 6.6 4.4 2.3 18.5 10.1 1.0 1.6 3.4 0.9 0.6 0.3 0.4 THUMPD1 "FLJ20274, Tan1" ENSG00000066654 "THUMP domain containing 1" Q9NXG2 16 20702816-20742084 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027851 Approved Approved Cytosol NA NA 9300000 "Cluster 2: Granulocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" Cytosol "HPA027851: AB_10670036" "unprognostic (1.67e-1)" "unprognostic (1.62e-1)" "prognostic favorable (2.99e-4)" "unprognostic (1.48e-1)" "unprognostic (3.69e-1)" "unprognostic (2.50e-1)" "unprognostic (4.17e-2)" "unprognostic (4.40e-2)" "unprognostic (2.10e-2)" "unprognostic (1.73e-2)" "unprognostic (6.88e-2)" "unprognostic (2.45e-1)" "prognostic favorable (8.52e-8)" "unprognostic (1.98e-1)" "unprognostic (5.95e-2)" "unprognostic (1.09e-1)" "unprognostic (1.25e-2)" 16.0 16.4 10.9 14.4 11.4 21.2 38.3 12.4 14.2 23.0 12.3 23.0 13.3 25.3 28.3 15.2 21.8 15.6 11.4 11.3 12.8 22.8 17.0 16.6 21.0 10.6 10.9 23.5 18.9 30.5 13.8 17.6 10.4 33.4 18.5 20.6 19.6 22.8 17.1 15.7 17.6 24.4 11.2 18.3 23.3 16.4 12.9 20.7 20.2 20.3 20.7 20.0 19.2 12.0 22.4 22.8 41.9 23.7 35.7 31.3 25.2 22.0 22.8 20.7 20.4 17.6 23.2 53.9 42.0 25.0 19.5 21.3 27.7 29.6 32.5 32.0 16.0 49.0 20.5 43.3 23.6 79.2 100.2 25.5 40.0 22.5 25.3 23.8 24.1 24.0 95.7 41.5 23.9 25.3 38.7 32.3 35.3 20.5 14.2 51.6 38.0 43.8 24.4 17.9 31.8 21.7 18.2 32.1 23.4 25.5 22.4 28.4 23.1 28.9 17.1 19.8 21.9 42.6 43.2 38.5 21.9 22.7 24.6 13.3 6.4 19.3 15.3 7.4 19.5 10.7 15.6 15.0 6.4 9.7 19.7 17.7 2.9 14.3 8.3 5.5 12.4 9.4 10.9 11.4 12.4 14.2 11.3 12.8 10.6 10.9 10.4 11.2 12.9 12.0 55.6 41.7 48.5 16.3 66.6 48.4 37.5 27.1 57.5 37.0 62.7 48.8 30.3 42.9 38.2 31.3 20.9 61.0 81.6 35.6 39.2 29.8 5.9 66.2 64.3 47.9 36.5 23.5 25.6 34.4 35.3 45.5 26.5 97.0 72.1 42.7 42.1 45.2 30.0 35.3 24.7 38.3 26.4 34.8 35.2 8.9 41.0 34.3 33.8 20.6 45.5 45.1 55.6 21.1 32.6 27.5 33.8 67.7 41.3 52.0 32.2 49.7 39.8 37.0 46.0 50.9 50.7 44.1 66.3 46.6 55.4 73.1 72.5 25.5 44.9 35.6 TIGAR C12orf5 ENSG00000078237 "TP53 induced glycolysis regulatory phosphatase" Q9NQ88 12 4307763-4360028 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Autophagy" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hofbauer cells: 59.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 47.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034010, HPA040354, HPA044111" Approved Supported Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB034010: AB_1128227, HPA040354: AB_2676935, HPA044111: AB_2678814" "unprognostic (1.76e-1)" "unprognostic (6.33e-2)" "unprognostic (4.08e-1)" "unprognostic (2.60e-1)" "unprognostic (1.32e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (3.18e-4)" "unprognostic (5.41e-2)" "unprognostic (2.11e-1)" "unprognostic (9.37e-2)" "unprognostic (1.85e-1)" "unprognostic (5.21e-2)" "unprognostic (2.03e-2)" "unprognostic (2.02e-3)" "unprognostic (2.44e-1)" "unprognostic (3.31e-1)" "unprognostic (1.05e-1)" 3.8 5.4 1.4 1.9 1.6 1.9 2.9 1.9 3.0 1.8 1.8 3.7 0.7 2.8 1.2 3.7 2.3 1.4 5.0 2.2 1.6 4.2 3.1 3.7 2.0 1.9 2.0 1.1 2.0 0.9 5.3 1.4 2.1 2.8 1.7 2.3 3.0 1.7 5.8 2.5 3.6 2.1 2.1 5.3 3.3 3.5 1.9 1.7 2.3 2.0 1.9 3.5 2.4 2.3 4.1 9.9 4.8 7.7 10.9 6.3 47.3 9.3 8.0 5.3 7.3 5.7 3.8 4.1 0.7 5.8 5.2 5.7 5.8 7.6 7.0 3.8 2.9 0.1 4.7 7.8 14.3 2.1 0.5 8.1 12.9 5.9 6.8 3.2 14.5 3.4 0.3 2.2 9.2 7.7 2.2 0.8 8.6 5.5 1.7 3.0 6.4 1.0 6.7 5.0 0.2 2.8 7.9 3.2 10.1 22.0 0.8 1.6 10.5 8.2 5.9 5.6 3.8 1.4 2.1 6.9 5.4 0.8 5.7 0.5 1.7 0.2 0.7 3.5 0.5 0.9 0.7 0.8 1.9 1.3 0.6 0.7 1.5 0.8 3.4 1.6 1.4 0.6 1.4 1.6 1.9 3.0 2.2 1.6 1.9 2.0 2.1 2.1 1.9 2.3 10.7 0.0 1.7 0.0 14.7 0.0 13.8 0.0 5.7 4.2 6.2 7.5 10.5 1.5 0.0 5.5 18.8 27.4 16.9 5.0 15.6 15.6 28.0 4.7 5.9 9.4 7.3 1.3 0.0 13.9 28.5 6.6 11.7 4.8 0.0 4.5 5.0 5.6 59.3 1.7 0.0 1.5 0.0 20.4 0.0 27.8 3.7 30.6 0.0 0.0 34.9 11.5 7.2 0.0 0.0 17.5 2.6 4.5 16.3 9.5 2.9 11.7 0.0 3.3 6.6 5.7 8.3 19.9 22.3 8.1 0.0 34.3 11.8 10.8 2.3 15.6 TKTL1 "TKR, TKT2" ENSG00000007350 "Transketolase like 1" P51854 X 154295795-154330350 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "testis: 127.1" "Group enriched" "Detected in some" 7 "Spermatocytes: 166.9;Spermatogonia: 491.5" "Cancer enriched" "Detected in many" 8 "testis cancer: 44.2" "Group enriched" "Detected in some" 5 "cerebral cortex: 4.3;medulla oblongata: 1.7" "Group enriched" "Detected in many" 5 "eosinophil: 60.9;gdT-cell: 24.4" "Group enriched" "Detected in many" 5 "granulocytes: 60.9;T-cells: 24.4" "Cell line enriched" "Detected in some" 163 "THP-1: 495.2" "Not detected" "Not detected" "Region enhanced" "Detected in single" "white matter: 1.2" "HPA000505, HPA029155, CAB032191" Enhanced Enhanced Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 74: Testis - Spermatogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Cytosol "CAB032191: , HPA000505: AB_1858022, HPA029155: AB_10603134" "unprognostic (2.69e-1)" "unprognostic (1.92e-1)" "unprognostic (1.98e-1)" "unprognostic (5.80e-3)" "unprognostic (2.43e-1)" "unprognostic (1.83e-1)" "unprognostic (1.36e-2)" "unprognostic (1.00e-1)" "unprognostic (2.10e-2)" "unprognostic (1.61e-1)" "unprognostic (1.98e-1)" "unprognostic (2.01e-1)" "unprognostic (1.63e-1)" "unprognostic (1.34e-2)" "unprognostic (3.90e-2)" "unprognostic (5.04e-2)" "unprognostic (2.38e-1)" 0.3 0.1 0.3 0.4 0.4 0.9 0.2 0.2 4.3 0.3 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.1 3.8 0.3 0.3 0.3 0.2 1.0 0.4 1.7 0.2 0.1 0.0 0.0 0.9 0.3 0.6 0.1 0.0 2.2 0.0 0.0 0.3 0.2 0.1 0.1 0.5 0.7 0.0 127.1 0.5 0.4 0.1 0.5 0.1 0.1 0.1 0.5 0.3 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.6 0.0 0.0 495.2 0.0 0.0 0.0 0.1 0.2 0.0 3.0 2.7 0.0 0.0 0.4 1.6 0.1 60.9 24.4 0.4 3.5 0.1 2.9 2.2 0.0 0.1 6.0 5.4 1.0 7.8 0.3 0.2 3.5 5.8 0.3 0.4 0.2 4.3 0.3 0.3 1.7 0.2 0.6 0.5 0.5 0.5 0.2 0.0 0.0 0.7 0.5 0.3 0.0 0.0 0.6 0.3 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 44.8 0.0 0.1 0.7 0.0 0.4 0.4 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.1 0.2 25.2 0.4 0.0 0.0 0.3 3.7 22.5 4.1 1.9 0.0 1.0 0.6 6.0 20.6 1.0 0.1 0.0 0.0 1.9 1.3 0.0 0.0 0.1 0.0 1.0 26.3 1.4 1.6 166.9 491.5 0.1 0.1 0.0 4.1 0.1 0.0 0.0 TMC3 ENSG00000188869 "Transmembrane channel like 3" Q7Z5M5 15 81331088-81374213 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 30 "parathyroid gland: 83.6" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.7;Distal tubular cells: 1.9;Excitatory neurons: 1.0;Spermatocytes: 1.1" "Cancer enhanced" "Detected in single" "breast cancer: 0.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA040265, HPA040510" Enhanced Supported Cytosol NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 25: RPMI-8226 - Immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" Cytosol "HPA040265: AB_10795379, HPA040510: AB_10796123" "unprognostic (1.17e-2)" "unprognostic (3.43e-1)" "unprognostic (3.14e-1)" "unprognostic (8.33e-2)" "unprognostic (1.22e-2)" "unprognostic (1.63e-2)" "unprognostic (4.85e-3)" "unprognostic (2.20e-2)" "unprognostic (3.12e-2)" "unprognostic (1.77e-1)" "unprognostic (6.20e-5)" "unprognostic (2.32e-1)" "unprognostic (1.97e-7)" "unprognostic (1.60e-1)" "unprognostic (5.31e-2)" "unprognostic (1.26e-1)" "unprognostic (5.96e-2)" 0.1 0.2 0.7 0.4 0.7 0.8 0.4 2.4 0.9 0.3 0.3 0.4 0.6 0.4 1.6 0.1 0.9 0.6 0.2 0.6 0.2 0.2 0.3 0.1 0.4 0.7 1.0 0.4 0.2 83.6 0.1 0.2 2.7 0.4 0.1 0.7 0.6 0.5 0.2 0.4 0.4 0.1 0.5 0.3 0.2 0.7 0.5 0.1 0.8 0.1 0.1 0.1 0.8 0.7 0.3 0.3 0.1 0.9 0.1 0.0 0.6 0.2 0.1 0.0 0.1 0.2 0.6 0.8 0.0 0.0 0.8 0.2 0.1 0.0 0.0 0.5 0.5 0.6 0.3 0.3 0.1 0.5 0.3 0.1 0.0 0.1 0.1 0.4 0.0 0.9 0.2 1.0 0.0 0.3 0.3 0.4 0.5 0.3 0.3 0.2 0.3 1.5 0.0 0.2 0.3 0.6 0.2 0.3 0.6 0.2 0.7 0.3 0.1 0.5 0.6 0.4 0.2 1.5 0.6 0.5 0.3 0.8 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.1 0.2 0.1 0.7 0.7 2.4 0.9 0.6 0.2 0.7 1.0 2.7 0.5 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.1 0.6 0.1 0.6 0.0 0.0 1.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMCO3 "C13orf11, FLJ20623" ENSG00000150403 "Transmembrane and coiled-coil domains 3" Q6UWJ1 13 113491021-113554590 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 20.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039561, HPA048126" Uncertain Approved Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol "HPA039561: AB_2676573, HPA048126: AB_2680276" "unprognostic (7.89e-2)" "prognostic unfavorable (5.80e-4)" "unprognostic (6.78e-2)" "unprognostic (7.88e-2)" "unprognostic (2.89e-1)" "unprognostic (6.01e-2)" "prognostic unfavorable (1.14e-5)" "unprognostic (2.93e-2)" "unprognostic (9.44e-2)" "unprognostic (3.08e-3)" "unprognostic (2.76e-2)" "unprognostic (8.47e-3)" "unprognostic (3.70e-3)" "unprognostic (1.05e-1)" "unprognostic (2.06e-1)" "unprognostic (6.27e-3)" "prognostic unfavorable (4.10e-4)" 24.2 26.9 20.5 18.6 18.3 76.7 22.7 29.8 21.5 31.1 49.2 23.1 21.0 33.1 20.0 14.4 25.2 27.7 28.2 17.3 16.3 24.2 14.3 24.3 16.3 19.4 18.8 25.2 40.7 35.1 23.1 30.1 19.4 22.1 22.0 18.1 38.7 21.6 19.1 13.4 22.7 29.6 19.6 19.8 44.3 16.1 19.6 12.4 10.7 15.2 13.1 19.6 18.9 21.2 97.8 32.6 46.3 32.0 93.1 136.4 25.0 105.0 99.6 45.1 45.3 35.7 41.9 23.1 25.9 115.7 61.7 38.5 24.8 38.0 70.0 48.0 25.1 20.9 52.2 36.0 87.9 34.3 41.7 112.0 88.5 33.9 68.9 116.7 74.5 14.3 30.3 31.6 79.6 17.5 18.0 20.6 23.2 46.5 50.9 22.4 28.0 16.7 74.3 12.6 40.4 33.5 32.3 70.3 33.6 65.3 41.5 64.6 117.4 50.3 53.5 36.9 44.8 39.2 23.9 14.8 167.2 17.8 24.6 3.1 8.3 8.5 1.3 5.6 1.5 3.1 1.5 2.0 6.0 1.8 1.7 1.7 20.2 5.0 11.3 1.3 1.5 2.7 20.5 18.3 29.8 21.5 17.3 16.3 19.4 18.8 19.4 19.6 19.6 21.2 34.3 12.8 15.1 21.5 12.5 9.8 37.2 25.8 21.6 16.4 39.2 17.5 20.3 24.3 27.8 25.8 14.6 21.6 13.5 37.1 5.9 46.8 14.6 28.2 39.2 31.3 34.2 23.5 42.9 37.4 53.8 35.0 39.3 28.6 26.6 18.4 35.0 12.4 19.1 21.9 41.0 69.2 12.2 31.3 18.8 37.1 36.7 24.5 17.8 12.2 31.4 25.9 17.5 24.6 31.9 52.6 28.2 47.8 19.2 64.0 20.0 11.2 45.2 19.0 6.6 26.2 31.9 17.6 12.2 15.9 7.1 13.0 11.8 34.4 17.7 31.3 TMEM121 "hole, MGC4659, TMEM121A" ENSG00000184986 "Transmembrane protein 121" Q9BTD3 14 105526583-105530202 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 31.2;Muller glia cells: 14.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "EFO-21: 8.1;MCF7: 8.1;PC-3: 10.2;REH: 6.7;SCLC-21H: 5.3;WM-115: 5.4" "Low region specificity" "Detected in all" HPA049857 Uncertain Approved Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA049857: AB_2680917" "unprognostic (4.25e-2)" "unprognostic (3.34e-1)" "unprognostic (2.05e-3)" "unprognostic (2.20e-2)" "unprognostic (1.31e-1)" "unprognostic (9.50e-2)" "unprognostic (1.88e-3)" "unprognostic (9.54e-2)" "unprognostic (3.47e-2)" "unprognostic (1.20e-1)" "unprognostic (1.03e-3)" "unprognostic (5.31e-2)" "unprognostic (5.48e-4)" "unprognostic (2.83e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (5.87e-4)" "unprognostic (5.90e-2)" 2.0 1.0 4.8 0.5 5.0 0.2 2.4 2.9 6.4 4.6 0.4 2.4 0.2 4.3 0.1 1.0 4.6 0.1 2.3 5.7 3.1 2.6 2.6 1.7 0.3 5.8 4.8 2.4 2.4 0.6 5.1 0.2 3.8 3.7 0.0 0.0 1.4 0.4 0.3 1.5 1.8 0.2 2.6 3.4 1.8 1.2 3.3 0.1 2.6 0.0 0.0 2.1 2.1 3.9 0.0 4.0 0.4 3.6 0.0 0.2 0.7 2.4 0.5 0.4 0.0 0.0 1.3 1.2 8.1 0.0 0.7 0.4 0.4 0.1 0.0 0.5 1.9 0.0 0.4 1.4 0.6 0.0 1.4 0.2 0.0 0.1 0.0 0.2 0.4 0.5 0.1 0.0 0.2 8.1 0.2 0.0 1.2 0.1 10.2 6.7 0.0 0.1 0.1 0.0 5.3 2.0 0.4 0.0 2.0 0.0 2.4 0.3 1.4 1.1 2.1 0.2 0.4 0.6 0.0 0.0 0.1 0.5 5.4 0.0 0.0 0.0 0.6 0.0 1.0 2.1 1.2 0.6 0.2 0.6 0.7 0.4 0.0 0.8 0.0 0.0 0.0 0.2 4.8 5.0 2.9 6.4 5.7 3.1 5.8 4.8 3.8 2.6 3.3 3.9 10.6 0.0 0.5 2.3 2.8 4.6 2.6 0.1 2.2 5.1 8.9 10.8 1.5 1.5 0.7 5.5 0.0 0.2 0.7 0.0 0.0 1.0 1.7 5.4 5.5 9.5 0.0 3.4 5.7 0.2 2.2 4.6 1.1 1.4 0.0 31.2 10.8 2.3 0.4 10.1 4.8 0.0 0.0 0.6 4.8 2.2 4.4 0.4 7.2 2.8 0.0 14.4 1.0 12.1 11.5 0.0 0.0 6.4 0.5 1.8 0.0 0.1 1.6 1.6 0.0 4.0 3.2 0.7 3.1 0.4 2.6 0.3 3.2 1.8 0.2 0.6 TMEM134 FLJ21749 ENSG00000172663 "Transmembrane protein 134" Q9H6X4 11 67461710-67469272 "Predicted membrane proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043744 Approved Supported Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "HPA043744: AB_10794773" "unprognostic (1.44e-1)" "unprognostic (1.08e-1)" "unprognostic (1.22e-1)" "unprognostic (4.67e-2)" "unprognostic (8.66e-2)" "unprognostic (1.39e-1)" "unprognostic (1.10e-1)" "unprognostic (7.22e-2)" "unprognostic (3.85e-1)" "unprognostic (1.39e-2)" "unprognostic (4.30e-2)" "unprognostic (3.48e-1)" "unprognostic (1.75e-1)" "unprognostic (3.12e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-2)" "unprognostic (4.43e-3)" 12.6 24.3 22.5 8.6 23.2 4.7 14.8 21.2 29.9 15.6 19.9 14.0 8.3 9.6 11.0 55.5 10.2 6.5 46.8 21.6 22.2 25.2 33.9 11.2 11.9 22.8 22.6 8.6 42.9 7.9 8.7 5.3 22.4 25.7 4.5 2.8 20.6 7.3 57.4 57.5 14.5 4.4 22.7 16.2 22.4 26.5 22.9 6.6 13.5 26.0 8.8 15.9 25.4 22.5 12.3 4.6 6.5 14.0 4.3 7.3 7.2 2.5 4.6 2.9 1.2 5.8 14.3 11.7 27.2 6.2 9.2 10.0 2.9 10.7 1.8 11.3 4.9 2.2 4.5 5.9 6.6 2.3 3.2 7.3 13.4 2.3 7.7 12.7 3.0 7.9 3.0 6.6 6.3 29.0 13.3 8.6 11.0 20.4 16.3 6.5 3.8 38.5 11.3 12.5 6.0 13.3 9.1 14.2 28.6 4.4 34.5 2.3 5.8 10.4 9.0 12.5 3.3 27.8 19.4 8.2 15.6 3.0 8.5 58.2 54.3 98.5 71.4 132.7 78.8 203.7 84.2 80.6 66.6 195.7 85.6 80.6 25.7 90.2 176.0 87.3 123.9 73.3 22.5 23.2 21.2 29.9 21.6 22.2 22.8 22.6 22.4 22.7 22.9 22.5 43.3 16.0 41.5 11.8 83.0 90.0 87.7 177.7 99.0 29.3 139.9 173.4 53.4 60.1 93.5 68.0 10.4 69.5 46.5 64.7 133.1 95.0 50.2 53.0 35.3 36.6 71.4 22.3 9.4 126.0 147.9 31.3 120.3 73.4 23.4 52.5 29.3 69.6 84.0 11.8 8.2 100.3 97.6 43.6 49.3 46.2 20.8 49.0 110.3 2.8 61.2 39.5 63.8 9.5 14.1 189.9 81.7 24.8 47.2 142.6 150.8 148.9 75.0 29.5 6.6 24.4 45.9 105.8 80.1 185.1 180.1 72.8 53.3 37.6 73.5 152.2 TMEM161A "FLJ20422, FLJ39645" ENSG00000064545 "Transmembrane protein 161A" Q9NX61 19 19119169-19138513 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043365 Approved Approved Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 59: Non-specific - Translation" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA043365: AB_10796793" "unprognostic (4.31e-2)" "unprognostic (9.13e-2)" "unprognostic (2.34e-2)" "unprognostic (7.42e-3)" "unprognostic (6.60e-2)" "unprognostic (1.57e-1)" "unprognostic (1.12e-2)" "unprognostic (3.51e-2)" "unprognostic (2.04e-1)" "unprognostic (2.74e-1)" "unprognostic (9.42e-2)" "unprognostic (2.46e-1)" "unprognostic (9.15e-2)" "prognostic favorable (2.99e-4)" "unprognostic (4.18e-1)" "unprognostic (2.79e-1)" "unprognostic (4.89e-3)" 13.0 22.5 4.5 4.4 4.6 5.4 13.6 4.8 6.9 19.8 7.1 15.8 3.5 21.7 1.5 14.8 17.6 5.4 17.7 4.3 4.3 15.3 25.9 12.3 4.8 6.9 4.6 17.7 15.7 13.7 8.2 3.3 5.4 14.3 3.7 2.5 14.9 7.1 50.7 16.9 11.2 6.3 4.4 10.4 14.7 6.3 5.4 5.8 19.5 13.2 4.8 14.3 15.9 5.9 28.9 19.3 12.6 20.1 24.8 17.1 12.8 13.4 12.8 16.4 20.1 17.5 30.8 26.4 57.9 9.4 11.3 23.9 20.6 29.3 11.4 9.9 47.6 10.0 10.6 24.0 30.9 9.1 14.7 26.9 23.9 15.6 25.9 14.9 17.9 30.5 31.6 27.2 12.5 33.8 19.5 24.7 9.9 37.1 19.6 33.4 9.4 44.8 13.0 13.0 13.0 13.6 20.2 20.1 15.7 9.1 17.1 24.0 7.6 13.3 5.3 34.4 21.1 27.8 14.9 16.1 13.9 22.5 20.7 1.3 6.1 1.4 8.2 5.3 6.7 4.3 7.5 6.2 8.4 5.6 8.8 6.3 1.1 5.4 7.1 19.4 11.4 4.1 4.5 4.6 4.8 6.9 4.3 4.3 6.9 4.6 5.4 4.4 5.4 5.9 15.7 6.4 18.3 5.5 9.5 6.1 15.1 27.1 14.8 15.7 13.4 15.4 8.7 20.0 18.3 11.0 10.4 19.8 14.8 6.5 7.9 20.5 1.2 8.8 14.1 11.3 5.4 6.7 10.9 12.9 15.1 14.6 14.8 9.5 15.9 15.1 9.7 25.3 16.3 16.8 11.4 10.0 10.2 9.5 4.1 1.5 11.8 7.5 12.4 5.6 6.8 15.8 8.2 4.5 8.4 11.9 7.5 17.7 13.6 14.9 12.5 29.1 11.8 14.5 13.1 13.5 14.3 8.7 8.4 12.4 8.7 12.3 11.4 33.8 19.3 10.0 TMEM40 FLJ11036 ENSG00000088726 "Transmembrane protein 40" Q8WWA1 3 12733528-12769457 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 219.8;skin 1: 64.7;vagina: 80.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 104.7;Cytotrophoblasts: 128.3;Macrophages: 121.3;Squamous epithelial cells: 116.5;Suprabasal keratinocytes: 201.9;Syncytiotrophoblasts: 656.6;Urothelial cells: 157.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 13.3;urothelial cancer: 12.1" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "neutrophil: 6.0" "Lineage enriched" "Detected in single" 7 "granulocytes: 6.0" "Cell line enhanced" "Detected in many" "HBEC3-KT: 244.9;hTCEpi: 56.1;hTERT-HME1: 68.0;RT4: 36.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA044165, HPA073122" Enhanced Approved Cytosol NA NA 2500000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA044165: AB_10961279, HPA073122: " "unprognostic (2.51e-3)" "unprognostic (1.96e-2)" "unprognostic (2.64e-3)" "unprognostic (8.25e-2)" "unprognostic (2.27e-1)" "unprognostic (1.92e-1)" "unprognostic (5.15e-4)" "unprognostic (5.96e-2)" "unprognostic (3.15e-1)" "unprognostic (2.60e-1)" "unprognostic (1.81e-3)" "unprognostic (2.47e-1)" "unprognostic (1.20e-3)" "unprognostic (1.41e-1)" "unprognostic (1.70e-1)" "unprognostic (1.46e-2)" "unprognostic (6.77e-2)" 0.1 0.1 0.4 0.0 0.4 3.3 3.2 0.5 0.6 42.1 0.3 0.0 0.1 0.1 1.3 219.8 3.1 0.1 4.2 0.5 0.3 0.2 0.3 2.1 0.1 0.4 0.3 0.1 0.1 3.2 0.2 15.9 0.3 3.7 0.0 0.1 27.3 2.5 1.3 64.7 0.0 0.1 0.1 1.8 0.2 0.8 0.4 1.5 0.1 0.6 25.9 15.2 80.1 0.3 26.6 0.1 0.0 0.1 0.0 0.0 22.4 0.2 1.1 1.3 1.4 1.0 4.1 0.1 0.2 0.0 0.6 7.6 0.0 244.9 5.1 0.2 0.0 1.9 0.2 0.8 0.0 0.0 0.0 0.0 56.1 0.0 68.0 0.4 0.0 0.0 0.1 0.0 0.0 7.7 0.0 0.0 0.0 0.2 4.3 0.0 1.6 0.0 1.6 36.0 0.2 0.2 0.1 31.3 0.0 4.6 2.8 0.7 0.0 0.0 1.6 0.0 2.1 0.3 0.1 0.4 0.1 0.0 0.0 1.6 0.9 1.1 0.0 0.1 0.5 0.0 0.0 0.0 0.2 0.0 0.2 0.0 6.0 0.0 0.0 0.8 0.0 32.9 0.4 0.4 0.5 0.6 0.5 0.3 0.4 0.3 0.3 0.1 0.4 0.3 0.1 0.0 0.0 0.3 0.3 64.2 104.7 71.7 17.6 0.0 1.5 5.6 4.7 0.0 39.4 1.8 0.0 128.3 0.0 0.1 0.0 0.5 0.8 2.9 0.0 1.8 0.0 0.0 0.3 0.0 14.7 1.8 0.0 0.1 0.0 0.0 2.2 0.7 10.8 0.0 0.3 0.0 12.2 4.8 7.3 2.0 0.3 121.3 10.6 0.0 2.6 0.0 2.1 0.0 0.2 2.2 0.0 0.0 0.0 53.5 0.0 0.0 55.0 0.0 0.0 0.1 3.6 0.7 6.8 116.5 201.9 656.6 1.0 0.2 0.0 157.9 TMEM44 DKFZp686O18124 ENSG00000145014 "Transmembrane protein 44" Q2T9K0 3 194587673-194633689 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 31.2;Hepatic stellate cells: 53.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "basophil: 3.7;NK-cell: 8.1" "Group enriched" "Detected in many" 10 "granulocytes: 3.7;NK-cells: 8.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043718 Uncertain Approved Cytosol "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA043718: AB_10794662" "unprognostic (8.94e-2)" "unprognostic (1.01e-1)" "unprognostic (8.31e-3)" "unprognostic (4.53e-2)" "unprognostic (2.78e-3)" "unprognostic (9.29e-2)" "unprognostic (2.11e-3)" "unprognostic (1.17e-2)" "unprognostic (1.70e-2)" "unprognostic (3.37e-2)" "unprognostic (1.48e-2)" "unprognostic (4.75e-3)" "prognostic unfavorable (6.55e-13)" "unprognostic (1.23e-2)" "unprognostic (3.36e-1)" "unprognostic (1.65e-3)" "unprognostic (5.66e-2)" 10.3 2.9 9.8 2.3 11.7 5.2 8.9 7.8 12.4 6.9 7.1 11.0 2.7 5.6 13.7 5.6 5.4 4.5 9.6 10.3 10.1 6.0 3.4 11.3 3.0 9.9 9.7 4.9 3.5 0.9 2.6 7.4 10.0 5.2 7.2 0.6 7.7 2.2 3.2 3.6 6.8 3.2 8.8 9.3 4.9 2.2 10.5 2.0 5.6 2.3 1.6 5.3 5.9 9.2 11.1 9.1 13.4 14.2 4.8 16.2 11.8 8.2 15.3 6.8 10.8 5.0 21.8 2.0 38.9 10.0 20.3 12.6 4.5 6.4 4.6 18.1 6.3 12.4 10.6 3.8 8.7 3.9 18.9 10.0 6.8 15.4 6.8 32.8 28.2 12.1 3.4 0.5 22.9 10.1 5.9 9.9 6.9 11.1 14.8 11.5 8.4 0.3 7.2 6.3 3.7 7.7 6.1 1.9 12.6 5.6 9.0 8.5 33.7 20.8 7.6 6.4 11.2 1.5 1.2 4.0 31.4 15.0 10.4 3.7 0.2 0.2 0.4 0.1 0.0 0.1 0.1 0.6 0.0 0.2 0.0 0.2 0.4 8.1 0.3 0.4 0.0 0.0 9.8 11.7 7.8 12.4 10.3 10.1 9.9 9.7 10.0 8.8 10.5 9.2 22.0 0.0 2.3 3.3 2.1 0.5 3.3 4.9 1.8 0.9 2.8 2.3 1.7 1.5 6.0 5.5 2.1 9.5 1.7 31.2 0.0 5.7 0.6 2.3 3.7 23.8 6.0 4.0 12.7 4.9 4.0 6.0 22.4 2.0 17.7 10.6 53.2 0.6 3.5 0.0 5.4 25.2 6.1 1.3 3.4 0.3 3.1 1.5 1.8 12.2 0.1 0.5 2.1 2.5 1.5 14.9 21.0 1.9 1.3 6.0 3.9 0.4 7.5 0.6 6.6 1.8 3.6 0.5 6.5 2.4 0.6 8.8 1.9 6.0 21.0 6.3 TOB2 "APRO5, bK223H9, TOB4, TOBL, TROB2" ENSG00000183864 "Transducer of ERBB2, 2" Q14106 22 41433494-41446801 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016603, HPA054112" Approved Approved Cytosol NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 54: Non-specific - Microtubule organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA016603: AB_2669400, HPA054112: AB_2682385" "unprognostic (1.21e-3)" "unprognostic (3.10e-2)" "unprognostic (3.41e-1)" "prognostic favorable (3.08e-5)" "unprognostic (3.89e-2)" "unprognostic (1.38e-1)" "unprognostic (1.36e-1)" "unprognostic (5.36e-2)" "unprognostic (4.94e-2)" "unprognostic (5.74e-2)" "unprognostic (3.18e-2)" "unprognostic (1.17e-1)" "prognostic favorable (1.18e-6)" "unprognostic (1.50e-2)" "unprognostic (7.14e-2)" "unprognostic (1.85e-1)" "unprognostic (7.13e-2)" 46.1 31.3 39.3 15.6 56.3 9.7 25.5 78.1 40.1 26.5 18.5 30.1 22.4 25.0 11.8 26.6 38.4 28.8 41.2 39.3 43.8 24.6 27.1 20.7 18.5 61.7 42.9 38.0 29.0 35.6 22.8 22.0 44.0 26.6 15.5 55.0 17.2 19.4 86.5 27.1 23.9 20.1 39.5 20.6 30.5 13.6 52.0 19.6 36.1 68.1 19.7 23.3 21.0 71.9 36.8 16.6 28.5 19.4 65.4 45.5 27.5 23.9 36.7 29.8 26.2 21.9 17.0 22.4 23.5 34.8 11.6 31.4 26.7 13.4 27.1 23.0 34.2 12.3 23.9 33.4 44.8 33.5 15.9 42.1 22.5 35.6 15.4 30.1 30.2 7.6 18.9 24.5 24.6 40.8 13.9 19.2 24.4 48.1 17.6 29.7 19.2 19.4 21.3 25.3 13.1 8.8 60.0 32.2 44.6 17.7 17.9 16.5 37.9 29.3 27.1 23.0 22.7 22.9 10.7 12.2 17.8 14.2 19.7 3.9 5.9 4.1 7.5 8.0 7.1 10.0 6.2 6.3 5.3 7.5 3.2 4.7 3.8 3.8 8.4 8.0 5.5 6.1 39.3 56.3 78.1 40.1 39.3 43.8 61.7 42.9 44.0 39.5 52.0 71.9 48.5 48.1 59.6 48.6 61.4 126.8 66.6 24.3 105.3 56.0 83.1 56.9 59.8 58.6 31.7 47.8 64.6 34.7 56.9 76.9 23.5 29.7 41.1 88.6 59.3 45.3 54.3 16.8 12.2 19.1 37.3 54.1 42.3 116.9 34.1 13.7 52.5 29.7 19.6 25.2 15.1 67.7 10.2 22.0 117.9 61.6 66.8 51.4 53.4 14.0 34.6 58.3 18.6 10.1 43.6 32.3 60.0 82.0 26.2 73.6 103.6 29.2 45.9 105.2 52.6 97.4 60.9 23.8 28.9 88.7 136.7 63.3 57.4 19.6 61.9 92.2 TOLLIP IL-1RAcPIP ENSG00000078902 "Toll interacting protein" Q9H0E2 11 1274371-1309654 "Plasma proteins, Predicted intracellular proteins" "Autophagy, Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 498.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038621, HPA038622" Enhanced Approved Cytosol NA NA 140000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA038621: AB_10673177, HPA038622: AB_10675946" "unprognostic (8.39e-2)" "unprognostic (1.89e-1)" "unprognostic (2.18e-2)" "unprognostic (6.08e-2)" "prognostic unfavorable (5.45e-4)" "unprognostic (8.89e-2)" "unprognostic (2.51e-1)" "unprognostic (8.53e-2)" "unprognostic (2.17e-1)" "unprognostic (1.55e-2)" "unprognostic (1.90e-2)" "unprognostic (2.74e-1)" "prognostic favorable (1.11e-16)" "unprognostic (2.72e-1)" "unprognostic (1.46e-1)" "unprognostic (3.21e-2)" "unprognostic (1.29e-2)" 26.8 35.4 58.2 12.4 73.5 13.6 25.8 27.5 80.9 35.9 17.6 26.3 25.5 23.5 11.5 93.4 22.4 18.4 31.3 85.0 39.4 43.1 113.3 26.6 14.2 39.9 39.1 24.6 58.2 18.9 54.2 12.1 39.8 31.4 8.2 11.4 31.6 20.5 76.2 75.9 23.4 11.1 32.9 28.8 31.9 73.4 42.7 13.2 24.7 22.7 14.2 33.5 48.8 56.5 31.4 32.6 16.3 18.6 34.0 21.2 14.2 27.2 24.5 31.3 27.7 35.4 19.5 14.6 25.6 25.3 47.9 27.7 14.7 33.4 8.5 30.1 30.1 11.9 6.9 54.2 48.4 22.8 29.0 32.1 38.5 18.6 17.9 17.1 19.7 21.7 19.9 38.5 26.1 26.3 29.1 27.9 20.0 33.9 42.1 21.8 16.6 14.6 20.9 41.3 43.5 25.5 24.4 29.4 30.7 8.3 23.3 25.7 36.0 33.8 14.4 14.4 16.0 38.8 37.8 18.3 53.2 14.9 27.0 45.4 126.6 139.6 33.4 114.0 27.8 38.8 35.3 31.5 99.9 50.0 27.4 26.1 179.1 44.5 108.8 52.4 48.8 77.3 58.2 73.5 27.5 80.9 85.0 39.4 39.9 39.1 39.8 32.9 42.7 56.5 19.5 9.6 19.3 15.0 27.8 66.9 43.9 71.7 23.3 42.6 30.3 24.6 22.8 58.6 30.9 23.9 8.4 49.2 28.0 50.8 70.5 66.3 173.6 11.7 14.8 24.9 51.6 45.0 35.1 69.2 41.1 27.6 19.4 15.8 38.1 20.7 37.9 112.2 92.1 74.0 17.0 30.8 48.8 38.4 33.1 498.2 21.8 48.3 71.2 16.9 50.6 38.1 19.6 10.6 15.0 76.3 53.7 30.9 33.4 55.7 66.6 110.1 15.4 20.6 6.6 18.5 24.5 100.7 39.6 76.3 98.9 104.4 22.0 27.4 29.3 74.0 TP53INP1 "DKFZp434M1317, FLJ22139, P53DINP1, SIP, Teap, TP53INP1A, TP53INP1B" ENSG00000164938 "Tumor protein p53 inducible nuclear protein 1" Q96A56 8 94925972-94949378 "Predicted intracellular proteins" "Apoptosis, Autophagy, Transcription, Transcription regulation" "Activator, Antioxidant" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 101.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 175.6;Plasma cells: 233.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 54.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 54.6" "Cell line enhanced" "Detected in many" "Karpas-707: 79.7;U-266/70: 85.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005856 Uncertain Supported Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "HPA005856: AB_10600832" "unprognostic (1.39e-2)" "unprognostic (4.47e-3)" "unprognostic (7.17e-2)" "unprognostic (2.70e-1)" "unprognostic (5.31e-2)" "prognostic favorable (1.11e-4)" "unprognostic (5.72e-2)" "unprognostic (1.16e-3)" "unprognostic (1.28e-1)" "unprognostic (7.54e-2)" "unprognostic (5.00e-3)" "unprognostic (1.23e-2)" "unprognostic (1.87e-2)" "unprognostic (9.83e-2)" "unprognostic (3.13e-1)" "unprognostic (1.18e-2)" "prognostic favorable (5.45e-5)" 11.2 10.6 6.4 23.1 7.9 42.1 12.7 6.0 7.6 11.8 9.7 16.5 17.2 12.7 12.6 10.9 14.7 10.9 10.9 5.5 6.5 11.5 101.9 25.3 36.0 8.5 6.8 9.0 60.4 10.1 7.1 14.4 7.0 22.5 20.2 17.6 17.9 9.2 9.2 13.1 35.5 12.2 7.0 40.6 25.6 28.6 8.0 29.3 10.2 8.6 41.1 13.3 8.7 8.8 0.5 2.5 24.1 9.3 29.4 27.6 24.8 5.8 13.5 2.6 6.2 2.2 0.6 5.3 12.4 11.2 2.3 4.2 0.0 9.5 5.8 0.3 3.0 3.4 5.3 14.8 19.7 0.0 16.8 45.4 22.2 6.9 2.8 22.4 39.8 2.6 1.8 79.7 12.4 1.7 4.0 1.5 2.3 0.1 0.7 3.4 1.9 29.4 6.3 26.5 3.3 19.5 3.6 2.0 5.2 38.5 11.8 3.3 27.6 4.8 5.8 0.0 0.9 85.4 18.9 2.3 8.4 0.0 0.0 54.6 3.7 11.7 1.4 3.6 1.3 11.5 4.0 2.7 1.4 9.7 0.8 0.6 16.9 5.2 2.3 1.4 6.6 2.5 6.4 7.9 6.0 7.6 5.5 6.5 8.5 6.8 7.0 7.0 8.0 8.8 18.5 35.3 35.7 10.7 70.0 4.6 3.0 17.9 8.0 5.2 27.4 11.6 13.2 75.8 27.9 11.0 27.1 6.1 10.1 27.5 3.9 9.3 17.3 39.9 18.1 14.2 83.9 6.7 0.9 21.3 1.5 11.4 11.2 35.9 4.5 18.8 29.3 175.6 12.5 1.7 2.9 20.9 20.3 44.2 5.6 43.3 7.2 12.6 16.0 16.9 17.7 5.3 3.1 12.1 11.0 18.0 32.2 10.1 233.2 18.1 21.6 9.6 66.4 19.8 6.6 11.0 12.7 18.9 5.6 10.8 6.5 5.7 17.9 26.8 4.8 8.7 TPH1 "TPH, TPRH" ENSG00000129167 "Tryptophan hydroxylase 1" P17752 11 18017564-18042426 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Serotonin biosynthesis" "Monooxygenase, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.0;intestine: 19.3;stomach 1: 15.0" "Cell type enriched" "Detected in many" 30 "Enteroendocrine cells: 1466.7" "Cancer enhanced" "Detected in some" "endometrial cancer: 2.4" "Group enriched" "Detected in some" 5 "hypothalamus: 3.4;midbrain: 9.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HL-60: 1.5" "Low region specificity" "Detected in some" "CAB010767, HPA022483" Uncertain Uncertain Cytosol NA NA "Cluster 9: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Cytosol "CAB010767: AB_261587, HPA022483: AB_1858378" "unprognostic (2.14e-4)" "unprognostic (9.97e-2)" "unprognostic (6.92e-2)" "unprognostic (6.78e-2)" "unprognostic (1.55e-1)" "unprognostic (6.26e-5)" "unprognostic (1.73e-1)" "unprognostic (5.33e-2)" "unprognostic (1.60e-1)" "unprognostic (2.12e-2)" "unprognostic (1.19e-4)" "unprognostic (6.72e-2)" "unprognostic (5.40e-8)" "unprognostic (3.76e-2)" "unprognostic (7.42e-2)" "unprognostic (3.10e-1)" "unprognostic (2.46e-5)" 0.6 0.1 0.2 1.2 0.3 1.1 1.3 0.3 0.3 0.6 4.7 9.0 10.2 0.9 0.9 0.2 0.9 0.1 0.3 0.4 3.4 0.5 0.2 0.8 0.5 0.2 9.0 0.7 0.5 0.1 3.0 0.2 1.1 1.4 19.3 1.8 0.5 0.1 0.4 1.4 11.2 0.2 0.2 0.7 15.0 0.9 0.4 0.3 0.5 0.1 0.7 0.4 0.4 0.3 0.1 0.0 0.5 0.4 0.0 0.0 0.2 0.1 0.1 0.0 0.3 0.6 0.0 0.4 0.1 0.0 0.0 0.2 0.1 0.5 0.2 0.4 1.0 0.7 0.3 1.1 0.0 1.5 0.3 0.0 0.6 0.0 0.2 0.1 0.2 0.8 0.3 0.2 0.0 0.1 0.3 0.2 0.1 0.0 0.1 0.5 0.0 0.0 0.0 0.3 0.4 0.3 0.0 0.1 0.2 0.0 0.0 0.9 0.0 0.1 0.4 0.1 0.5 0.0 0.1 0.3 0.0 0.3 0.4 0.3 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.3 0.3 0.3 0.4 3.4 0.2 9.0 1.1 0.2 0.4 0.3 1.4 0.0 0.0 1.0 1.1 0.4 0.4 0.5 0.0 14.9 1.9 1.0 0.8 0.0 0.1 5.5 2.1 0.2 0.6 1.7 0.0 0.2 0.8 0.1 0.6 0.7 1466.7 0.4 0.5 0.6 0.0 1.2 2.0 0.2 0.0 5.6 0.4 0.2 0.2 1.7 0.4 48.2 0.0 0.3 1.4 0.8 0.9 0.5 0.0 0.0 0.1 1.4 1.0 0.0 0.6 0.4 13.4 1.2 0.3 2.3 1.5 0.3 0.9 5.6 6.6 1.3 1.3 2.8 3.7 0.0 1.4 0.0 1.2 0.0 2.7 0.4 TPRKB "CGI-121, CGI121" ENSG00000144034 "TP53RK binding protein" Q9Y3C4 2 73729104-73737400 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "tRNA processing" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 259.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035712 Approved Supported Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA035712: AB_10669674" "unprognostic (1.11e-1)" "unprognostic (2.41e-2)" "unprognostic (6.59e-2)" "unprognostic (2.31e-2)" "unprognostic (2.74e-1)" "unprognostic (2.67e-2)" "unprognostic (1.21e-3)" "unprognostic (4.96e-2)" "unprognostic (3.16e-3)" "unprognostic (3.01e-3)" "unprognostic (5.10e-3)" "unprognostic (6.06e-2)" "unprognostic (2.68e-3)" "unprognostic (5.66e-2)" "unprognostic (8.45e-3)" "unprognostic (1.82e-1)" "unprognostic (5.03e-2)" 22.7 23.1 11.8 22.3 12.3 70.2 42.7 14.5 17.2 32.7 12.6 36.5 38.7 30.2 35.8 31.0 54.9 20.2 34.0 12.0 12.5 35.5 39.2 17.3 37.0 12.7 12.2 36.1 26.7 18.5 12.7 22.6 12.7 25.0 33.9 16.1 31.1 19.0 68.1 25.7 35.5 29.1 12.7 22.3 24.9 51.8 12.1 37.0 21.3 50.9 33.7 26.3 25.2 13.1 106.1 73.3 73.4 85.5 27.2 37.6 62.2 73.5 40.0 72.2 54.2 110.8 66.0 67.0 54.0 38.2 130.7 62.6 60.6 77.6 116.0 53.4 79.2 135.7 49.8 90.6 26.6 198.3 72.8 27.2 43.6 76.4 76.3 37.4 76.9 114.7 119.8 105.1 75.5 56.4 142.5 130.6 94.9 130.5 93.9 83.6 211.6 93.8 67.2 89.8 69.1 83.1 53.1 79.5 105.6 59.8 58.7 78.6 48.5 62.4 104.7 113.6 182.6 69.1 127.6 176.9 55.9 131.2 78.4 32.5 18.2 29.1 16.5 28.5 26.4 23.9 23.6 22.3 22.1 20.9 27.0 25.5 13.1 24.6 21.5 30.1 25.4 15.8 11.8 12.3 14.5 17.2 12.0 12.5 12.7 12.2 12.7 12.7 12.1 13.1 56.3 32.1 39.8 7.2 43.1 53.2 66.8 123.0 38.7 15.0 51.8 94.9 63.5 50.1 70.6 22.0 4.2 81.3 39.7 64.0 88.0 95.4 138.9 50.2 42.7 81.9 33.6 62.1 8.6 184.9 107.9 45.1 17.9 43.4 48.7 51.3 148.2 44.3 86.7 8.4 8.7 71.2 71.2 55.6 60.0 28.9 59.0 52.1 33.8 2.8 65.0 36.6 64.9 10.1 8.3 110.7 76.9 52.3 35.6 47.8 103.4 154.9 54.4 21.8 52.6 61.7 46.2 259.3 87.8 44.8 53.0 45.6 42.8 53.9 85.4 58.2 TPT1 "fortilin, TCTP" ENSG00000133112 "Tumor protein, translationally-controlled 1" P13693 13 45333471-45341284 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 23236.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008364, HPA039437" Approved Supported Cytosol NA NA 1500000 "Cluster 32: T-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Cytosol "CAB008364: AB_591904, HPA039437: AB_2676508" "prognostic favorable (5.90e-5)" "unprognostic (1.00e-1)" "unprognostic (1.16e-1)" "prognostic favorable (2.35e-4)" "unprognostic (3.25e-1)" "unprognostic (3.57e-2)" "unprognostic (8.71e-3)" "unprognostic (2.04e-1)" "unprognostic (1.08e-1)" "unprognostic (1.29e-3)" "unprognostic (4.56e-1)" "unprognostic (3.02e-1)" "prognostic unfavorable (2.54e-5)" "unprognostic (1.47e-1)" "unprognostic (8.48e-2)" "prognostic favorable (4.31e-5)" "unprognostic (6.51e-2)" 5808.9 3790.0 1970.1 2971.0 2089.0 7021.6 4788.5 2017.1 2885.0 4815.0 2151.1 3979.7 3896.8 3466.6 5086.2 4739.6 3764.4 3768.2 4538.7 1920.3 2182.7 4819.1 6862.2 3615.7 5627.2 2141.5 2042.0 6982.0 10645.5 2467.5 2595.3 4390.6 2185.5 3646.9 3385.7 1026.8 8474.6 2254.8 23236.6 3472.5 3896.8 2786.2 2206.2 3281.4 3544.7 821.0 1977.3 3910.4 4425.0 13885.5 4621.3 4859.8 4376.0 2225.8 1905.1 1684.0 2793.7 1836.1 8042.9 11121.9 3311.0 3946.8 6100.9 2460.2 2560.6 3800.8 4814.7 4011.0 3236.5 4125.5 1627.8 3232.7 2281.2 5785.6 3386.6 1869.7 2010.7 3227.6 1369.1 4278.1 8106.1 4451.8 4843.1 9204.7 11563.7 1572.6 9416.5 7957.8 5168.0 3360.7 2443.5 1080.9 5091.4 3449.9 5437.0 10564.3 3194.8 6358.1 1773.3 3370.4 2645.5 3062.6 6392.2 3916.9 1185.4 3165.1 1308.7 4147.6 6396.8 2827.9 2383.4 12710.0 3402.5 1129.5 1605.0 1855.4 2470.9 2644.9 2873.7 3842.4 3013.5 3486.9 899.6 1195.3 1271.4 617.3 1006.6 978.8 1830.5 1337.9 1874.2 1366.7 1138.9 1036.9 1944.6 1636.5 546.5 1513.4 929.3 1454.0 1812.0 3204.4 1970.1 2089.0 2017.1 2885.0 1920.3 2182.7 2141.5 2042.0 2185.5 2206.2 1977.3 2225.8 4176.2 1593.0 3381.6 39.5 4868.3 3494.9 6406.7 2737.1 4501.1 371.9 5018.7 4187.9 2795.4 3154.1 2226.0 763.2 160.6 4470.7 5693.8 3799.1 3144.1 2527.2 1185.2 3111.2 5482.8 3928.3 2068.2 3074.8 44.9 5125.2 6375.7 3310.5 2398.6 5369.5 1842.3 4305.3 5062.0 4784.7 4614.9 213.7 39.1 5716.8 852.4 5939.9 3637.5 1381.9 6800.4 6005.9 1773.4 87.1 6495.9 2240.9 5186.5 25.1 50.5 5271.4 5556.8 3870.4 4453.2 6953.8 11028.2 9311.2 1156.1 656.2 2530.9 5300.1 3028.9 443.5 687.3 5411.6 3479.1 5749.6 5238.7 4437.6 5420.4 9158.8 TRADD Hs.89862 ENSG00000102871 "TNFRSF1A associated via death domain" Q15628 16 67154185-67159909 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 163.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004602, HPA071341" Enhanced Approved Cytosol NA NA "Cluster 13: T-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 3: Monocytes - Immune response regulation" Cytosol "CAB004602: AB_2209061, HPA071341: AB_2732178" "unprognostic (2.66e-1)" "unprognostic (3.11e-1)" "unprognostic (2.23e-2)" "prognostic favorable (1.40e-4)" "unprognostic (1.50e-2)" "unprognostic (1.21e-1)" "unprognostic (5.68e-2)" "unprognostic (4.96e-2)" "unprognostic (4.15e-2)" "unprognostic (2.24e-1)" "unprognostic (2.82e-1)" "unprognostic (8.27e-3)" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "unprognostic (1.38e-1)" "unprognostic (7.24e-2)" "unprognostic (1.83e-1)" 15.4 19.4 9.5 12.8 10.5 4.9 15.6 10.9 10.2 17.8 10.8 17.4 8.4 14.2 3.7 26.9 16.6 4.1 11.2 9.9 8.8 22.2 18.4 17.6 12.4 13.2 10.0 10.5 17.8 7.0 12.1 6.7 12.4 21.2 5.6 1.1 23.8 6.2 6.3 22.5 19.2 4.9 11.3 29.9 19.1 5.0 10.1 7.4 18.1 2.1 10.6 18.2 17.9 12.0 17.3 14.0 0.2 4.8 12.6 10.0 16.8 12.6 9.5 6.0 9.3 8.2 13.0 9.0 21.8 11.0 12.6 29.0 2.0 11.4 4.9 26.1 12.8 5.7 6.4 9.0 15.7 7.3 13.7 10.5 16.0 8.0 3.1 15.3 11.8 8.7 8.4 13.1 9.1 15.5 8.8 14.5 0.2 16.0 42.2 17.1 6.6 36.4 10.4 10.9 2.2 8.1 28.6 6.4 9.0 4.7 11.0 10.3 13.2 7.5 8.2 13.3 9.5 26.3 9.4 10.6 19.9 6.5 9.4 51.9 42.4 95.1 54.4 56.2 84.2 72.0 166.0 96.2 54.2 71.8 46.7 38.5 75.7 40.7 78.6 76.4 82.1 49.5 9.5 10.5 10.9 10.2 9.9 8.8 13.2 10.0 12.4 11.3 10.1 12.0 24.0 3.2 8.6 3.9 37.7 17.3 22.9 60.2 12.5 0.9 29.8 25.0 3.5 30.0 32.8 5.5 0.0 32.0 47.9 24.9 31.3 70.0 1.4 31.0 18.1 20.5 19.2 9.9 1.8 38.1 41.5 22.3 44.9 27.6 8.9 25.9 17.2 19.2 47.0 0.0 2.4 28.2 38.7 37.7 35.0 2.9 30.1 28.6 56.9 0.0 163.4 5.0 48.4 1.0 8.3 62.0 35.7 30.5 52.5 57.7 28.1 80.3 40.7 2.1 26.3 16.0 21.9 2.2 7.6 29.7 25.7 30.5 46.7 23.3 23.8 42.1 TRAF2 "RNF117, TRAP3" ENSG00000127191 "TNF receptor associated factor 2" Q12933 9 136881912-136926607 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004603, HPA009972, HPA010634" Uncertain Enhanced Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 3: Monocytes - Immune response regulation" Cytosol "CAB004603: AB_628389, HPA009972: AB_1080350, HPA010634: AB_1080347" "unprognostic (7.77e-2)" "unprognostic (4.54e-3)" "prognostic unfavorable (9.32e-4)" "unprognostic (1.15e-1)" "unprognostic (1.11e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (3.06e-4)" "unprognostic (4.91e-2)" "unprognostic (7.23e-2)" "unprognostic (4.28e-2)" "unprognostic (7.39e-2)" "unprognostic (2.82e-2)" "prognostic unfavorable (2.09e-4)" "unprognostic (1.80e-3)" "unprognostic (5.52e-2)" "unprognostic (1.60e-1)" "unprognostic (1.53e-2)" 8.3 7.9 14.9 13.8 16.9 16.1 9.1 20.0 18.8 10.6 13.2 11.1 9.9 8.3 4.1 15.3 8.3 6.0 11.0 15.6 14.3 10.3 15.1 9.6 20.2 17.9 15.7 7.3 8.0 4.8 10.1 8.3 18.2 12.5 5.5 4.2 11.5 8.3 8.5 12.1 12.0 6.2 14.9 16.8 9.6 17.8 15.7 17.8 14.1 5.1 14.7 11.0 11.5 18.1 25.4 76.3 20.2 18.0 5.6 8.8 39.5 20.5 11.1 29.2 19.8 47.5 44.5 31.2 25.8 12.8 39.3 65.0 27.9 33.3 11.8 47.9 22.8 23.6 76.2 30.0 8.3 23.5 23.4 6.6 9.9 23.7 13.4 10.9 13.9 28.5 40.5 34.5 13.2 36.6 38.3 33.6 33.1 57.4 33.9 35.8 31.1 42.7 18.0 19.6 32.9 15.4 25.6 58.9 23.7 22.5 42.4 27.2 15.7 37.8 24.2 24.6 34.8 14.3 25.2 31.2 13.3 19.2 28.5 2.0 4.8 9.1 12.3 5.8 17.8 15.2 13.4 15.6 6.5 12.3 10.7 13.2 4.2 14.0 12.0 14.8 24.0 8.3 14.9 16.9 20.0 18.8 15.6 14.3 17.9 15.7 18.2 14.9 15.7 18.1 7.9 0.0 6.4 7.5 12.5 11.9 14.1 18.1 4.0 6.9 8.3 7.0 7.5 12.8 8.7 5.5 0.0 19.4 7.4 23.3 3.9 19.2 3.2 4.4 4.3 11.0 11.4 9.0 5.6 12.8 28.9 6.9 9.7 6.1 10.2 11.8 4.2 4.1 13.3 18.5 4.5 16.1 6.1 2.2 8.7 4.1 3.4 6.2 14.2 2.8 32.7 4.5 11.3 2.5 5.7 20.8 6.2 7.9 11.3 20.0 15.6 6.3 5.6 9.8 19.7 4.1 7.4 17.5 23.8 5.3 12.8 17.8 13.9 6.5 15.4 10.0 TRAM2 KIAA0057 ENSG00000065308 "Translocation associated membrane protein 2" Q15035 6 52497408-52577060 "Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 122.0;Plasma cells: 69.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "ASC diff: 250.1;ASC TERT1: 265.8;fHDF/TERT166: 253.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA035092, HPA057925" Approved Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "HPA035092: AB_10610562, HPA057925: AB_2683557" "unprognostic (2.32e-2)" "unprognostic (2.19e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (1.88e-4)" "unprognostic (1.12e-1)" "unprognostic (4.07e-2)" "unprognostic (8.90e-3)" "unprognostic (1.14e-1)" "unprognostic (1.65e-1)" "unprognostic (3.03e-1)" "unprognostic (3.01e-1)" "unprognostic (5.05e-1)" "prognostic unfavorable (1.41e-9)" "unprognostic (1.37e-2)" "unprognostic (1.60e-1)" "unprognostic (6.64e-2)" "unprognostic (1.19e-2)" 19.5 4.9 3.4 14.8 4.7 5.3 13.8 3.0 4.3 14.9 7.8 12.5 14.0 13.1 11.5 5.6 13.5 17.3 10.4 3.0 3.3 7.4 16.2 14.1 7.5 4.3 3.5 12.4 7.0 2.8 3.9 35.8 3.6 6.0 14.7 3.9 6.4 5.8 3.6 11.5 12.6 17.5 3.3 19.2 9.5 13.3 4.4 4.5 12.4 5.9 13.3 13.3 9.6 3.3 45.4 19.8 22.7 22.6 250.1 265.8 39.8 130.0 130.8 106.7 98.2 43.2 9.2 11.0 21.4 253.4 76.0 10.0 14.9 81.3 133.6 24.8 8.0 24.1 20.5 54.9 71.3 6.2 13.1 97.4 8.0 93.5 41.2 155.1 124.1 9.1 15.1 78.4 154.5 16.2 8.9 17.7 10.4 17.9 8.8 10.9 59.8 91.0 25.3 7.5 5.5 8.7 29.9 13.2 31.6 47.7 20.6 12.9 198.8 177.6 38.4 65.0 72.1 53.4 97.7 31.1 64.7 16.1 110.8 0.1 1.0 1.0 0.9 1.1 0.5 1.2 0.7 0.5 1.1 0.8 0.3 0.6 0.2 0.7 2.1 0.5 0.2 0.7 3.4 4.7 3.0 4.3 3.0 3.3 4.3 3.5 3.6 3.3 4.4 3.3 12.8 6.4 3.2 6.8 15.9 8.2 2.8 8.5 3.4 3.1 4.0 5.1 9.9 4.3 4.1 7.3 25.0 36.2 6.6 7.8 3.9 3.6 38.3 4.0 28.9 17.9 9.0 8.6 12.0 3.2 30.8 26.2 6.1 5.0 2.5 34.0 19.6 36.1 15.7 5.0 9.2 19.6 6.1 12.0 6.9 122.0 20.8 5.7 26.6 13.1 4.3 1.8 8.2 3.5 3.1 6.2 1.7 23.3 69.5 2.8 7.0 3.1 4.9 12.7 13.1 16.2 15.7 23.4 8.6 1.2 4.1 20.7 6.0 14.3 5.7 1.5 TRAPPC4 "PTD009, SBDN, TRS23" ENSG00000196655 "Trafficking protein particle complex 4" Q9Y296 11 119018763-119025454 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 335.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039752, HPA041371" Approved Approved Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA039752: AB_2676664, HPA041371: AB_2677439" "unprognostic (5.26e-2)" "unprognostic (5.00e-2)" "unprognostic (2.64e-1)" "unprognostic (1.18e-2)" "unprognostic (9.42e-2)" "unprognostic (7.12e-3)" "prognostic unfavorable (2.03e-5)" "unprognostic (1.07e-1)" "unprognostic (1.12e-1)" "unprognostic (2.36e-2)" "unprognostic (4.34e-2)" "unprognostic (2.01e-2)" "unprognostic (7.49e-3)" "unprognostic (3.64e-1)" "unprognostic (1.17e-1)" "unprognostic (6.28e-2)" "unprognostic (1.32e-1)" 20.8 37.8 14.6 4.3 14.8 8.2 20.2 15.3 18.6 17.9 15.5 22.9 8.4 17.9 11.8 21.3 18.0 5.2 27.2 14.4 16.7 36.8 26.1 19.5 8.1 15.6 15.0 15.5 25.5 13.5 29.2 5.6 15.0 20.8 6.1 9.2 18.9 12.3 38.3 19.6 23.6 4.0 15.3 22.1 22.6 31.5 14.7 16.9 17.6 18.2 6.1 19.3 16.0 16.2 15.5 14.1 16.9 20.2 25.2 19.3 8.7 59.6 44.3 45.6 40.0 35.1 6.4 18.6 40.3 27.2 23.6 14.5 32.0 25.9 32.9 31.5 15.3 28.5 14.2 40.0 33.4 25.3 14.8 25.1 29.2 40.1 30.1 23.5 42.3 20.7 34.7 7.3 28.8 38.6 30.0 24.9 13.7 30.0 44.4 26.3 13.1 25.9 34.7 20.2 7.4 16.2 10.5 13.1 15.4 19.8 58.5 21.5 24.9 10.5 18.8 13.1 19.7 9.2 18.9 45.9 11.8 20.1 18.5 68.3 37.0 77.0 50.8 45.8 53.5 59.1 59.6 59.8 37.2 55.5 54.7 59.6 32.6 54.6 58.3 52.4 96.4 61.2 14.6 14.8 15.3 18.6 14.4 16.7 15.6 15.0 15.0 15.3 14.7 16.2 50.3 38.5 34.4 7.5 38.8 51.4 59.1 166.1 37.5 60.1 38.4 38.7 30.8 41.5 83.4 71.7 14.6 90.7 61.1 30.4 140.8 107.6 41.9 46.0 39.1 47.7 67.6 45.3 9.0 76.2 56.5 45.1 15.3 33.2 62.1 335.0 46.1 21.8 80.4 38.7 11.7 33.5 152.5 27.3 30.7 16.4 44.4 33.1 30.2 10.3 76.3 88.5 41.2 10.1 15.0 103.4 44.3 60.9 26.9 51.1 83.0 206.1 89.0 61.2 46.0 21.6 82.2 78.2 67.0 28.7 59.0 87.3 52.7 49.1 36.8 52.4 TREX1 "AGS1, DRN3" ENSG00000213689 "Three prime repair exonuclease 1" Q9NSU2 3 48465811-48467645 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Exonuclease, Hydrolase, Nuclease" "Aicardi-Goutieres syndrome, Disease variant, Neurodegeneration, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 53.6;Club cells: 24.5;Ionocytes: 40.7;Langerhans cells: 22.6;Melanocytes: 24.9;Respiratory ciliated cells: 29.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 67.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035437, HPA046721" Supported Supported Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA035437: AB_10672092, HPA046721: AB_2732531" 9.9 14.3 32.7 16.5 33.4 28.7 12.2 33.2 42.1 13.8 39.8 12.4 11.1 7.7 11.4 19.2 15.5 13.8 10.7 33.0 32.7 12.2 12.8 13.8 26.6 33.0 34.2 7.4 13.1 11.3 20.6 8.4 34.3 16.6 9.9 1.9 36.5 15.4 9.7 26.4 12.0 7.0 33.8 25.0 13.7 4.0 33.5 18.1 8.4 13.8 18.1 13.1 10.4 33.7 19.2 18.1 13.3 10.3 18.1 17.5 0.0 6.7 29.5 46.9 67.5 0.3 21.8 23.8 11.7 24.4 44.8 21.4 0.9 27.2 6.7 19.9 1.6 13.5 58.1 0.5 20.1 12.8 9.3 16.2 2.5 25.9 9.8 9.8 20.4 16.9 0.0 32.6 20.7 0.4 17.3 8.6 0.1 11.0 11.2 14.4 4.9 43.2 13.4 3.8 0.1 8.1 21.8 29.6 15.4 0.9 0.8 20.3 22.2 8.5 9.2 21.8 14.2 26.4 16.9 10.4 21.5 25.4 7.5 7.7 142.3 11.0 32.6 119.2 18.7 86.8 43.0 31.4 125.9 87.5 40.3 33.8 82.2 30.9 94.6 99.1 43.3 78.6 32.7 33.4 33.2 42.1 33.0 32.7 33.0 34.2 34.3 33.8 33.5 33.7 0.0 0.0 0.5 6.8 2.1 9.1 0.0 53.6 0.6 0.0 0.0 0.0 6.3 0.0 24.5 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 4.6 0.0 1.7 2.3 0.0 0.0 4.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.8 40.7 0.0 22.6 0.0 0.0 2.0 24.9 5.6 0.0 0.0 0.0 1.0 5.9 0.0 1.1 0.0 3.9 0.0 0.0 0.0 29.9 0.0 0.0 0.0 4.2 0.0 0.0 2.7 13.9 0.0 2.6 0.0 1.5 0.0 TRIM39 RNF23 ENSG00000204599 "Tripartite motif containing 39" Q9HCM9 6 30326479-30343729 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051120, HPA059496" Uncertain Supported Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA051120: AB_2681348, HPA059496: AB_2684040" "unprognostic (2.90e-1)" "unprognostic (1.61e-2)" "unprognostic (2.79e-2)" "unprognostic (2.86e-2)" "unprognostic (6.38e-2)" "unprognostic (4.55e-2)" "unprognostic (1.46e-2)" "unprognostic (1.15e-2)" "unprognostic (3.47e-1)" "unprognostic (9.44e-2)" "prognostic favorable (2.50e-4)" "unprognostic (1.30e-2)" "unprognostic (4.69e-2)" "unprognostic (6.35e-3)" "unprognostic (1.46e-1)" "unprognostic (1.06e-1)" "unprognostic (2.39e-3)" 10.0 8.7 0.8 1.7 1.0 3.1 10.2 1.3 1.1 11.4 1.5 13.6 1.6 12.1 2.2 13.1 11.7 1.3 8.7 0.9 0.9 9.8 11.6 9.7 1.6 1.3 1.0 11.5 12.2 2.1 14.8 1.6 1.0 10.8 1.5 1.5 10.2 2.0 14.3 9.3 11.9 1.8 0.8 14.3 11.0 20.7 1.1 1.7 11.6 1.4 2.1 12.9 9.5 1.1 3.2 0.1 2.6 4.8 1.2 1.2 2.7 1.4 1.8 2.1 1.9 3.8 0.4 4.1 2.8 2.7 1.3 1.0 3.1 2.2 2.2 3.2 3.4 3.2 0.5 1.4 2.7 4.8 3.5 1.4 1.8 2.7 2.9 3.2 1.3 3.4 4.9 3.2 2.7 2.9 1.0 1.0 3.6 1.3 2.2 2.2 0.5 3.1 2.2 3.0 5.7 2.8 1.1 2.3 2.8 2.5 3.1 1.2 1.2 2.3 1.8 2.8 4.9 5.7 7.6 4.2 1.3 1.7 3.6 1.0 0.9 4.1 2.7 1.3 2.4 1.8 1.9 2.0 0.9 1.6 2.2 2.2 4.5 2.6 1.4 0.7 1.7 1.4 0.8 1.0 1.3 1.1 0.9 0.9 1.3 1.0 1.0 0.8 1.1 1.1 5.9 3.2 7.2 0.7 14.2 3.7 5.6 2.6 6.8 6.0 7.5 5.2 5.6 2.8 3.5 1.8 6.2 4.7 11.9 5.5 7.9 4.6 4.6 11.2 4.1 4.8 5.4 3.6 0.9 6.1 5.7 4.1 15.3 13.1 5.7 4.2 5.7 3.7 3.3 3.3 1.1 7.3 4.1 7.2 5.0 7.8 2.8 7.3 3.6 1.0 4.3 6.9 8.2 0.5 0.9 6.8 10.0 4.5 10.9 3.7 7.5 4.0 7.2 7.6 0.0 3.8 5.8 19.1 10.0 5.3 4.1 10.0 15.3 3.5 4.4 5.3 TRIM39-RPP21 ENSG00000248167 "TRIM39-RPP21 readthrough" 6 30328907-30346854 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Alveolar cells type 1: 3.2;Alveolar cells type 2: 2.0;Club cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051120 Uncertain Approved Cytosol NA NA "Cluster 11: Alveolar cells - Smell perception" Cytosol "HPA051120: AB_2681348" "unprognostic (1.20e-1)" "unprognostic (7.35e-2)" "unprognostic (2.56e-1)" "unprognostic (1.60e-1)" "unprognostic (4.60e-1)" "unprognostic (1.33e-1)" "unprognostic (1.56e-1)" "unprognostic (5.84e-4)" "unprognostic (7.39e-2)" "unprognostic (1.50e-1)" "unprognostic (6.89e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 TRIM40 RNF35 ENSG00000204614 "Tripartite motif containing 40" Q6P9F5 6 30136124-30148735 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "intestine: 3.0;liver: 1.6;testis: 1.4" "Group enriched" "Detected in some" 5 "Distal enterocytes: 20.1;Paneth cells: 24.7" "Cancer enhanced" "Detected in some" "colorectal cancer: 0.7;stomach cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 12 "HEL: 1.1" "Region enriched" "Detected in single" 18 "thalamus: 3.1" "Low region specificity" "Detected in many" HPA043818 Uncertain Approved Cytosol NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 36: HEL - Hemostasis" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA043818: AB_10963090" "unprognostic (2.88e-1)" "unprognostic (5.20e-2)" "unprognostic (4.11e-1)" "unprognostic (1.13e-1)" "unprognostic (1.77e-1)" "unprognostic (4.84e-2)" 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 20.1 0.0 0.0 0.2 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.7 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 24.7 0.0 0.0 0.0 3.8 0.5 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 TRIM47 "GOA, RNF100" ENSG00000132481 "Tripartite motif containing 47" Q96LD4 17 75874164-75878581 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 105.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPMI-8226: 48.4;RPTEC TERT1: 36.0;U-266/70: 39.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA014933 Uncertain Supported Cytosol NA NA "Cluster 13: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 1: Pancreatic cells - Digestion" Cytosol "HPA014933: AB_10603219" "prognostic favorable (6.54e-4)" "unprognostic (8.42e-2)" "unprognostic (1.42e-1)" "unprognostic (2.42e-2)" "unprognostic (1.19e-2)" "unprognostic (4.07e-2)" "prognostic unfavorable (5.59e-5)" "unprognostic (2.08e-2)" "unprognostic (9.18e-3)" "unprognostic (2.74e-1)" "unprognostic (1.18e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (9.69e-5)" "unprognostic (3.94e-2)" "unprognostic (1.44e-2)" "unprognostic (3.01e-2)" "unprognostic (9.98e-2)" 20.6 10.3 43.4 6.5 45.1 0.3 17.7 39.9 68.1 20.4 38.8 31.9 9.0 29.2 3.9 19.1 17.6 7.6 26.7 41.7 42.3 39.2 17.8 18.9 4.3 50.1 46.8 7.2 18.0 5.8 8.8 2.6 43.1 16.8 4.5 0.8 24.4 4.9 6.8 19.9 19.6 6.1 41.5 28.9 17.4 7.4 53.0 1.8 12.8 4.5 4.3 31.4 21.4 45.7 20.6 14.8 0.1 0.1 3.2 3.4 0.5 0.8 1.6 1.1 0.9 2.8 10.2 0.0 12.9 0.7 10.1 23.4 3.7 5.5 0.1 13.2 9.4 0.1 10.2 28.3 5.3 0.1 0.1 2.8 1.5 2.3 2.0 1.0 10.1 1.6 2.2 30.3 0.6 3.5 2.0 0.3 1.6 7.9 29.1 1.5 1.8 48.4 36.0 0.7 5.8 0.4 6.1 29.1 8.4 0.8 3.5 0.6 15.6 18.0 11.3 1.8 7.1 39.2 12.1 2.5 7.8 0.0 1.7 0.0 0.0 1.4 1.7 0.0 4.6 2.4 4.0 2.2 0.1 2.1 2.6 1.7 0.0 2.2 0.0 1.2 5.4 0.6 43.4 45.1 39.9 68.1 41.7 42.3 50.1 46.8 43.1 41.5 53.0 45.7 34.3 16.0 5.4 26.4 5.2 18.0 39.8 34.8 34.1 6.0 20.8 23.4 4.8 40.0 13.8 16.5 0.0 0.5 2.6 30.2 19.6 67.5 0.5 13.6 17.7 39.6 8.4 1.3 1.9 76.6 1.4 33.7 22.4 12.6 22.2 17.1 43.5 11.4 63.5 0.0 1.4 12.5 57.0 9.1 14.5 1.0 34.2 8.2 42.7 8.4 2.6 10.3 0.0 5.5 5.8 105.2 4.7 19.2 12.5 57.0 42.0 66.3 16.7 0.9 32.9 14.5 36.4 1.0 2.2 22.1 15.9 0.8 7.9 2.0 11.8 19.2 TRIM5 "RNF88, TRIM5alpha" ENSG00000132256 "Tripartite motif containing 5" Q9C035 11 5663195-5938619 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Antiviral defense, Autophagy, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "CAB013497, HPA023420, HPA023422" Approved Supported Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB013497: , HPA023420: AB_1856378, HPA023422: AB_1856379" "unprognostic (2.60e-1)" "unprognostic (9.62e-2)" "unprognostic (2.04e-2)" "unprognostic (1.41e-2)" "unprognostic (6.88e-2)" "unprognostic (4.74e-3)" "unprognostic (5.48e-3)" "unprognostic (5.82e-2)" "unprognostic (1.49e-1)" "unprognostic (6.76e-3)" "unprognostic (8.54e-3)" "unprognostic (1.64e-1)" "unprognostic (2.20e-2)" "unprognostic (1.90e-1)" "unprognostic (1.09e-1)" "unprognostic (1.07e-2)" "unprognostic (6.12e-2)" 8.8 10.9 2.1 8.1 2.3 3.8 8.0 2.0 2.4 11.8 7.2 7.2 7.4 11.7 18.4 7.7 9.4 6.9 5.7 2.0 3.3 9.0 12.8 11.8 8.4 4.0 3.5 11.4 13.3 4.2 3.8 9.6 3.4 8.5 7.7 1.9 14.0 9.1 1.9 5.5 8.5 11.3 3.0 10.4 7.8 8.3 3.5 9.4 9.6 4.0 8.9 8.2 8.6 2.9 7.7 15.4 19.2 12.4 24.0 22.5 5.4 18.0 35.0 37.3 50.0 13.8 13.5 5.5 13.3 18.8 27.6 13.0 18.4 25.8 14.9 9.6 5.1 15.2 10.4 9.5 20.2 11.5 15.3 15.4 22.7 10.5 31.3 22.9 52.8 8.9 16.9 12.2 32.1 4.2 7.7 5.3 7.7 11.7 8.1 14.3 4.7 1.5 23.7 14.4 0.5 1.1 11.8 18.4 6.8 20.7 9.3 6.6 43.3 13.9 20.2 3.6 4.2 9.4 7.9 1.9 10.9 6.8 15.4 10.7 7.6 11.6 3.6 7.8 3.0 3.1 2.8 2.8 9.4 2.6 1.8 3.7 7.7 4.1 8.0 7.0 2.2 4.1 2.1 2.3 2.0 2.4 2.0 3.3 4.0 3.5 3.4 3.0 3.5 2.9 14.2 6.4 14.0 4.9 8.7 5.2 9.5 9.7 9.6 0.2 8.3 6.5 4.9 2.8 13.4 11.0 0.0 7.8 16.4 5.5 5.9 10.6 5.0 8.6 12.6 14.8 1.2 8.4 3.0 8.8 10.5 12.4 6.1 12.5 0.0 11.9 15.4 13.9 6.4 0.0 1.4 9.7 4.1 12.2 7.1 3.8 7.8 10.8 3.6 19.7 10.8 7.0 14.4 3.0 1.0 8.1 4.9 7.5 6.7 10.1 7.4 6.3 3.7 0.1 19.7 6.5 10.9 5.2 3.3 7.0 5.4 7.8 7.5 20.6 7.5 9.9 TRIM50 "FLJ32804, TRIM50A" ENSG00000146755 "Tripartite motif containing 50" Q86XT4 7 73312536-73328082 "Enzymes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "pancreas: 29.1;parathyroid gland: 33.3;stomach 1: 48.7" "Cell type enhanced" "Detected in some" "Early spermatids: 2.3;Gastric mucus-secreting cells: 17.9;Spermatocytes: 5.2;Spermatogonia: 4.2" "Group enriched" "Detected in some" 8 "liver cancer: 2.9;renal cancer: 6.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 32 "Hep G2: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA019862, HPA047843" Uncertain Approved Cytosol NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Cytosol "HPA019862: AB_1858305, HPA047843: AB_2680176" "unprognostic (1.93e-1)" "unprognostic (3.93e-1)" "unprognostic (1.07e-2)" "unprognostic (5.96e-2)" "unprognostic (3.87e-1)" "unprognostic (2.66e-2)" "unprognostic (1.49e-1)" "unprognostic (3.04e-3)" "unprognostic (2.63e-2)" "unprognostic (2.00e-1)" "unprognostic (2.13e-1)" "unprognostic (1.33e-1)" "prognostic favorable (9.36e-7)" "unprognostic (3.91e-2)" "unprognostic (1.60e-1)" "unprognostic (1.20e-1)" "unprognostic (2.25e-1)" 0.5 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.2 1.1 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 6.8 0.3 0.1 0.0 0.1 0.1 0.2 29.1 33.3 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.9 0.0 0.1 0.4 48.7 8.7 0.1 0.0 0.3 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.1 2.3 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.1 0.0 17.9 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.8 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 5.2 4.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 TRIM73 TRIM50B ENSG00000178809 "Tripartite motif containing 73" Q86UV7 7 75395063-75410996 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 21.6" "Cell type enhanced" "Detected in many" "Granulosa cells: 41.9;Horizontal cells: 32.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 6.0;Hep G2: 10.5" "HPA047843, HPA051845" Uncertain Uncertain Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA047843: AB_2680176, HPA051845: AB_2681635" "unprognostic (1.01e-2)" "unprognostic (9.85e-5)" "unprognostic (4.72e-3)" "unprognostic (9.44e-3)" "unprognostic (2.49e-1)" "unprognostic (1.48e-2)" "unprognostic (1.25e-3)" "unprognostic (9.17e-3)" "unprognostic (1.41e-1)" "unprognostic (2.80e-1)" "unprognostic (5.46e-3)" "unprognostic (6.79e-2)" "unprognostic (4.18e-2)" "unprognostic (9.67e-2)" "unprognostic (1.15e-1)" "unprognostic (4.78e-2)" "unprognostic (2.73e-3)" 2.8 3.7 1.0 1.3 1.7 2.5 3.5 4.7 2.1 5.0 0.7 2.1 3.6 2.9 0.5 1.4 6.4 1.1 2.0 1.0 1.4 4.2 5.6 1.9 2.3 1.1 1.0 4.3 6.0 1.3 3.6 0.4 1.1 4.5 0.2 0.9 2.1 1.6 2.6 2.4 3.3 0.2 0.8 3.2 21.6 11.3 1.3 1.1 4.6 0.4 0.4 2.2 3.1 1.8 1.0 3.2 1.3 1.9 0.0 0.6 0.5 0.4 0.1 0.0 0.7 0.0 1.5 1.8 0.3 0.2 0.2 1.1 0.3 0.0 0.1 4.1 6.0 1.1 2.8 10.5 0.6 0.6 4.2 1.7 0.0 0.2 0.3 0.9 0.0 2.5 0.6 4.9 0.0 0.7 1.7 2.1 0.1 0.3 1.0 2.8 0.2 0.9 0.3 0.0 1.6 1.2 2.0 0.7 1.9 0.5 0.5 1.9 1.2 0.9 1.4 1.3 0.8 2.3 1.4 1.8 1.2 2.6 1.1 0.2 0.1 0.1 0.3 0.1 0.2 0.2 0.2 0.0 0.0 0.2 0.3 0.2 0.3 0.3 0.0 0.2 0.3 0.2 1.0 1.7 4.7 2.1 1.0 1.4 1.1 1.0 1.1 0.8 1.3 1.8 3.8 0.0 0.5 0.0 15.5 0.9 3.2 3.1 4.6 21.9 5.1 4.2 2.5 1.5 3.3 5.5 18.8 2.1 8.7 1.6 5.9 1.8 5.9 9.2 13.4 2.8 4.9 3.4 0.1 4.7 0.7 4.7 16.8 5.6 0.0 41.9 2.9 3.0 3.0 32.0 0.1 3.2 4.1 2.4 1.2 11.4 6.5 3.1 1.8 0.0 2.5 5.8 9.2 0.0 0.1 2.9 4.0 3.8 11.2 3.3 10.0 4.7 5.4 14.5 0.0 14.6 4.1 9.1 2.5 3.3 2.0 1.1 6.8 14.2 3.4 2.6 TRIM74 "MGC45440, TRIM50C" ENSG00000155428 "Tripartite motif containing 74" Q86UV6 7 72959485-72969466 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 10.2;testis: 6.6" "Cell type enhanced" "Detected in some" "Microglial cells: 1.9;Respiratory ciliated cells: 2.1;Spermatocytes: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 3.8;Hep G2: 2.8" HPA047843 Approved Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 22: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA047843: AB_2680176" "unprognostic (8.78e-3)" "unprognostic (3.78e-4)" "unprognostic (5.84e-3)" "unprognostic (1.95e-2)" "unprognostic (1.03e-1)" "unprognostic (8.26e-2)" "unprognostic (3.58e-2)" "unprognostic (1.26e-3)" "unprognostic (1.65e-2)" "unprognostic (3.68e-1)" "unprognostic (8.13e-3)" "unprognostic (1.98e-2)" "unprognostic (7.78e-2)" "unprognostic (7.05e-2)" "unprognostic (1.67e-1)" "unprognostic (1.63e-1)" "unprognostic (1.12e-3)" 0.9 1.6 1.2 0.6 1.4 1.0 1.2 2.5 1.6 1.8 0.8 0.8 1.3 1.2 1.2 0.5 2.5 0.5 0.7 1.3 1.4 1.7 2.6 0.7 1.2 1.5 1.3 1.8 2.5 0.5 1.7 0.1 1.3 1.9 0.3 0.6 0.7 0.5 0.5 0.9 1.3 0.4 1.2 1.2 10.2 6.6 1.2 0.6 1.5 0.2 0.3 0.8 1.2 1.8 0.0 0.1 0.7 0.7 0.2 0.0 0.0 0.4 0.0 0.1 0.2 1.0 0.7 0.5 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.4 3.8 0.6 0.0 2.8 0.1 1.3 1.6 0.3 0.2 0.0 0.2 0.5 0.0 0.9 0.5 2.2 0.0 1.1 0.4 1.9 0.0 0.0 0.8 0.9 0.3 0.4 1.1 0.4 0.3 0.3 0.4 0.0 0.8 0.1 0.0 0.6 1.4 0.1 0.5 0.2 0.0 1.7 1.4 0.3 0.5 0.7 0.3 0.1 0.0 0.1 0.1 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 1.4 2.5 1.6 1.3 1.4 1.5 1.3 1.3 1.2 1.2 1.8 0.0 0.0 0.5 0.3 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 TRMT61B FLJ20628 ENSG00000171103 "TRNA methyltransferase 61B" Q9BVS5 2 28849821-28870309 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026747, HPA026751" Enhanced Uncertain Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA026747: AB_1848782, HPA026751: AB_1848784" "unprognostic (1.01e-2)" "unprognostic (1.32e-2)" "unprognostic (1.63e-3)" "unprognostic (2.05e-2)" "unprognostic (3.32e-2)" "unprognostic (4.14e-2)" "prognostic unfavorable (3.61e-4)" "unprognostic (2.36e-2)" "unprognostic (2.55e-2)" "unprognostic (2.77e-1)" "unprognostic (2.52e-2)" "unprognostic (2.52e-2)" "prognostic favorable (9.61e-5)" "unprognostic (2.19e-1)" "unprognostic (1.43e-1)" "unprognostic (5.38e-2)" "unprognostic (2.34e-1)" 8.8 13.1 9.8 8.5 9.9 9.2 13.1 12.1 17.0 9.4 12.0 8.4 14.1 10.1 14.0 8.6 8.1 7.2 15.2 9.8 9.9 14.4 12.6 6.6 11.0 9.7 9.8 9.4 7.0 15.1 9.0 8.9 10.0 10.6 9.3 9.4 8.7 7.9 13.8 8.7 14.1 10.3 9.8 8.7 9.2 7.4 9.7 10.2 9.1 16.6 9.1 10.7 7.5 10.6 28.5 16.7 16.7 29.6 22.3 19.0 20.1 16.5 20.3 20.6 19.2 19.3 15.0 29.9 14.8 14.5 24.7 21.7 23.5 20.1 21.3 22.6 15.8 9.1 13.6 25.7 25.2 19.4 10.0 19.5 22.0 16.4 22.2 15.2 20.0 19.1 18.9 11.2 17.2 11.3 17.3 29.6 31.0 33.6 26.7 12.7 26.9 26.1 18.2 18.2 28.1 29.8 17.8 27.8 28.5 13.9 14.2 6.7 15.8 13.7 23.1 13.6 21.0 13.7 24.2 46.6 18.1 28.9 18.8 0.0 8.0 3.5 11.2 8.5 13.8 14.5 12.4 12.0 7.8 14.1 13.7 9.9 1.1 17.7 7.1 8.3 14.7 7.4 9.8 9.9 12.1 17.0 9.8 9.9 9.7 9.8 10.0 9.8 9.7 10.6 10.2 16.0 8.7 18.3 17.7 18.1 11.0 23.7 17.1 10.8 9.9 10.2 2.8 11.5 14.7 9.2 6.2 22.1 11.8 4.5 15.6 14.5 9.3 9.4 11.8 8.5 4.8 10.9 38.0 10.2 13.8 10.8 21.4 7.7 9.5 15.8 7.5 11.5 9.2 6.7 34.8 9.8 20.3 7.3 8.2 3.6 8.7 7.0 7.2 7.5 11.0 10.3 8.2 36.2 32.2 10.3 8.5 10.5 13.5 7.6 23.6 30.3 15.0 21.6 6.6 12.2 10.6 24.1 9.7 15.3 15.8 8.8 12.4 15.9 12.1 7.3 TRPC4AP "C20orf188, dJ756N5.2, DKFZp586C1223, DKFZP727M231, PPP1R158, TRRP4AP" ENSG00000100991 "Transient receptor potential cation channel subfamily C member 4 associated protein" Q8TEL6 20 35002404-35092807 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 138.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051197, HPA065061" Uncertain Approved Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 39: CACO-2 - Unknown function" "Cluster 59: Non-specific - Transcription" Cytosol "HPA051197: AB_2681384, HPA065061: AB_2685416" "unprognostic (3.00e-1)" "unprognostic (1.61e-1)" "unprognostic (4.06e-2)" "unprognostic (2.08e-2)" "unprognostic (2.40e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (6.25e-8)" "unprognostic (1.33e-1)" "unprognostic (5.56e-2)" "unprognostic (2.58e-1)" "unprognostic (1.95e-2)" "unprognostic (1.77e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (3.38e-1)" "unprognostic (3.19e-2)" "unprognostic (5.14e-3)" "unprognostic (1.10e-1)" 54.2 60.9 40.6 37.4 49.5 69.3 50.5 43.6 47.4 45.6 41.3 42.6 36.4 41.7 32.1 45.8 41.3 34.1 46.4 40.7 44.2 43.0 61.9 55.9 42.2 50.0 46.4 40.4 64.2 42.4 62.1 47.8 50.7 46.6 36.1 29.7 48.2 36.1 80.5 46.1 46.9 37.6 43.3 60.4 51.9 35.7 50.0 41.6 47.3 39.7 38.9 41.9 41.4 63.0 53.7 64.4 56.3 58.2 85.2 81.6 86.0 85.2 99.8 95.7 109.6 141.6 78.3 50.0 79.5 99.1 97.4 70.0 51.6 121.5 73.7 26.7 40.2 127.5 54.8 131.0 85.0 74.9 83.8 91.4 75.4 71.7 61.0 100.0 107.9 101.1 61.2 58.3 77.0 40.6 91.1 84.0 44.3 49.2 86.9 56.4 80.9 51.2 82.3 68.9 49.6 50.1 91.9 153.2 59.3 66.6 55.6 59.9 106.7 117.9 53.2 64.8 51.6 52.9 30.6 41.5 128.2 36.6 61.7 30.6 30.5 50.6 24.0 32.4 25.5 17.4 19.9 25.7 40.2 15.3 17.2 18.7 48.5 25.9 38.2 17.4 24.7 27.0 40.6 49.5 43.6 47.4 40.7 44.2 50.0 46.4 50.7 43.3 50.0 63.0 24.2 19.2 14.1 49.0 29.9 15.2 15.2 20.6 21.6 25.7 24.1 19.9 13.1 12.8 19.1 20.2 79.2 52.6 37.0 34.9 3.9 30.1 14.8 16.0 21.9 25.1 20.4 21.5 44.6 27.3 43.8 23.9 48.4 24.9 19.7 43.4 21.0 23.4 37.2 67.3 56.3 24.6 28.5 25.6 22.2 8.5 25.4 23.7 12.4 40.3 27.9 28.5 23.7 59.3 138.0 36.2 24.1 23.0 45.8 23.6 30.4 11.4 18.0 29.2 39.5 18.3 24.0 23.2 27.3 19.1 15.8 68.4 32.2 30.3 24.0 24.0 TSBP1 "C6orf10, TSBP" ENSG00000204296 "Testis expressed basic protein 1" Q5SRN2 6 32288526-32371912 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 61 "testis: 35.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "testis cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA047479, HPA057426" Approved Approved Cytosol NA NA "Cluster 74: Testis - Spermatogenesis" Cytosol "HPA047479: , HPA057426: " "unprognostic (1.00e-1)" "unprognostic (2.24e-1)" "unprognostic (1.05e-1)" "unprognostic (5.63e-2)" "unprognostic (2.86e-2)" "unprognostic (2.14e-1)" "unprognostic (1.55e-1)" "unprognostic (4.32e-4)" "unprognostic (2.42e-1)" "unprognostic (8.19e-2)" "unprognostic (6.56e-2)" 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 35.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.3 0.2 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TSC1 "hamartin, KIAA0243, LAM, TSC" ENSG00000165699 "TSC complex subunit 1" Q92574 9 132891348-132946874 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Cancer-related genes, Disease variant, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 133.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011568, CAB012481, HPA074132" Supported Enhanced Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB011568: AB_732752, CAB012481: , HPA074132: AB_2686666" "unprognostic (1.88e-1)" "unprognostic (1.51e-1)" "unprognostic (1.40e-2)" "unprognostic (2.56e-1)" "unprognostic (6.67e-2)" "unprognostic (4.23e-3)" "prognostic unfavorable (6.03e-6)" "unprognostic (1.96e-2)" "unprognostic (3.48e-2)" "unprognostic (1.24e-1)" "prognostic favorable (8.01e-4)" "unprognostic (1.84e-2)" "prognostic favorable (7.91e-4)" "unprognostic (9.49e-2)" "unprognostic (1.46e-1)" "unprognostic (2.35e-1)" "unprognostic (1.16e-1)" 11.8 14.5 6.1 5.2 6.0 9.0 12.2 8.3 6.8 13.7 3.6 13.4 5.1 12.0 6.5 10.1 11.8 5.4 14.0 6.0 5.1 13.1 10.9 11.4 6.3 4.5 5.2 18.2 12.8 7.4 16.2 9.3 4.9 13.1 7.1 8.3 11.4 5.4 14.9 15.8 12.6 7.9 1.1 14.9 12.2 22.8 4.5 6.7 17.3 14.6 8.6 11.4 12.7 4.4 8.3 9.7 13.0 10.7 13.0 12.2 24.2 10.3 17.6 11.5 11.0 16.5 9.5 19.4 4.7 20.9 17.0 21.0 15.4 11.0 11.3 9.4 8.2 6.1 19.9 13.6 15.6 9.4 8.0 13.6 8.2 14.3 17.4 11.1 13.0 16.9 11.1 10.2 12.9 15.4 8.3 7.8 17.8 12.1 7.8 9.9 24.5 11.0 5.0 10.7 6.4 10.0 12.7 7.9 6.2 15.2 14.4 5.5 13.8 18.1 10.8 11.4 7.7 5.7 13.8 18.5 10.3 5.2 8.2 2.1 2.3 2.8 3.2 3.8 3.5 0.9 1.7 2.9 1.7 1.2 2.9 2.6 0.9 3.0 1.8 0.9 3.1 1.5 6.1 6.0 8.3 6.8 6.0 5.1 4.5 5.2 4.9 1.1 4.5 4.4 14.7 22.4 27.2 35.3 10.8 7.5 6.2 5.1 9.6 26.6 11.2 9.5 29.2 7.2 10.3 11.0 37.5 15.1 13.5 7.1 13.7 11.7 45.9 18.0 22.2 12.7 16.8 15.8 53.6 7.2 24.0 14.0 14.3 25.8 8.8 27.4 9.7 5.9 9.2 25.2 59.0 10.0 10.2 7.7 7.9 133.1 15.5 12.8 12.4 19.7 10.8 9.7 7.2 30.7 47.8 12.5 7.9 11.3 12.4 9.0 8.9 7.3 16.2 24.4 19.7 19.5 15.4 22.4 20.0 11.8 8.7 21.1 11.9 23.2 10.6 11.0 TSC2 "LAM, PPP1R160, TSC4, tuberin" ENSG00000103197 "TSC complex subunit 2" P49815 16 2047967-2089491 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "GTPase activation" "Cancer-related genes, Disease variant, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002225, HPA030409, HPA049679" Approved Enhanced Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Cytosol "CAB002225: AB_564043, HPA030409: AB_10602483, HPA049679: AB_2680848" "unprognostic (2.80e-1)" "unprognostic (1.01e-1)" "unprognostic (1.60e-2)" "unprognostic (2.24e-1)" "unprognostic (1.02e-1)" "unprognostic (1.03e-3)" "unprognostic (2.04e-2)" "unprognostic (6.05e-3)" "unprognostic (3.43e-1)" "unprognostic (8.94e-2)" "prognostic favorable (5.06e-4)" "unprognostic (4.32e-2)" "unprognostic (3.91e-2)" "unprognostic (2.14e-2)" "unprognostic (2.54e-1)" "unprognostic (1.51e-2)" "unprognostic (8.96e-2)" 12.6 10.0 3.8 10.2 4.6 10.9 12.6 4.5 6.1 16.7 0.9 15.3 12.4 17.4 7.3 12.0 16.0 10.9 12.6 5.9 1.3 9.6 9.0 12.0 7.7 3.1 1.5 18.4 14.8 14.7 16.5 9.2 2.7 12.4 9.1 17.7 21.3 15.6 31.1 14.4 12.8 11.4 0.1 11.4 15.7 16.2 2.6 11.7 18.6 14.5 7.8 14.0 12.8 12.5 13.5 21.4 28.9 32.5 33.7 28.1 24.3 31.7 21.7 23.4 19.7 25.7 25.4 20.5 27.6 26.2 11.0 22.0 17.5 23.1 17.3 15.5 28.5 19.2 39.6 10.7 23.0 24.0 22.4 33.5 14.3 18.9 13.9 27.9 22.3 14.4 19.0 17.7 21.0 27.0 28.9 7.1 29.8 10.1 21.2 45.3 31.6 25.7 9.4 12.1 22.1 41.3 45.2 29.4 15.3 28.2 26.8 17.5 35.5 24.5 16.5 22.0 16.5 39.0 42.7 40.8 10.2 9.7 29.6 3.2 2.7 2.8 3.1 2.1 2.8 1.8 1.9 1.7 2.5 1.8 1.3 2.1 3.5 1.6 1.7 0.6 1.4 2.2 3.8 4.6 4.5 6.1 5.9 1.3 3.1 1.5 2.7 0.1 2.6 12.5 23.8 25.6 18.9 43.8 16.8 9.2 8.1 10.1 14.8 53.8 23.7 20.2 41.8 21.5 15.3 20.2 93.8 13.0 17.3 34.5 3.9 15.2 13.1 47.8 26.3 25.6 32.5 17.4 22.8 14.1 8.0 19.7 44.9 62.1 8.8 49.0 32.2 38.7 11.4 45.4 22.4 26.6 8.2 17.6 9.9 29.3 28.3 13.8 8.8 15.9 12.1 19.0 36.0 18.6 25.7 21.4 17.5 25.9 14.4 9.4 25.4 8.9 17.8 64.7 13.1 17.2 20.4 18.3 37.7 12.9 9.8 9.3 18.8 31.6 28.9 10.6 TSC22D2 "KIAA0669, TILZ4a, TILZ4b, TILZ4c" ENSG00000196428 "TSC22 domain family member 2" O75157 3 150408335-150466431 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004926 Approved Approved Cytosol NA NA 100000 "Cluster 39: Non-specific - mRNA processing" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 44: Endometrium - Transcription" Cytosol "HPA004926: AB_1080401" "unprognostic (4.65e-2)" "unprognostic (1.54e-1)" "unprognostic (2.19e-1)" "prognostic unfavorable (2.74e-4)" "unprognostic (2.49e-1)" "unprognostic (2.65e-2)" "unprognostic (1.89e-1)" "unprognostic (1.09e-2)" "unprognostic (7.63e-2)" "unprognostic (2.59e-1)" "unprognostic (2.28e-3)" "unprognostic (8.32e-2)" "prognostic unfavorable (5.80e-4)" "unprognostic (1.10e-2)" "unprognostic (4.86e-1)" "unprognostic (1.10e-2)" "unprognostic (3.49e-1)" 20.9 11.8 8.1 10.7 8.9 34.9 13.2 9.9 15.2 18.9 3.3 14.9 6.0 23.4 14.4 23.8 15.4 22.6 21.5 9.1 9.0 15.9 29.6 15.0 10.3 8.5 8.8 15.2 11.4 10.8 9.8 16.9 9.0 11.4 12.4 16.7 10.6 7.3 17.0 11.1 11.9 26.3 6.1 13.8 16.3 17.8 6.6 11.8 12.9 14.4 9.9 20.6 23.3 11.1 45.7 6.2 19.6 18.8 25.1 12.2 56.4 44.6 16.9 32.1 39.5 25.0 22.4 14.9 25.1 33.7 65.7 18.9 19.8 16.2 63.7 11.8 11.1 16.0 11.6 12.7 28.5 9.8 10.6 22.6 12.4 20.9 31.4 19.4 20.4 7.1 27.7 23.9 22.6 16.1 10.5 12.1 25.1 13.6 12.3 11.0 35.8 17.7 20.7 26.6 11.3 10.1 20.5 10.8 45.8 23.5 10.3 13.0 33.0 21.1 21.9 25.3 41.6 31.9 6.6 20.6 14.3 29.2 12.7 0.5 1.7 2.0 1.1 1.6 1.8 1.1 1.4 1.2 1.1 1.4 1.1 1.1 2.2 2.0 2.9 1.2 0.6 1.5 8.1 8.9 9.9 15.2 9.1 9.0 8.5 8.8 9.0 6.1 6.6 11.1 97.4 64.1 30.8 160.3 52.5 148.9 81.5 12.6 111.0 18.6 65.1 28.4 46.9 20.0 18.2 12.9 29.2 28.6 53.7 77.6 17.6 13.8 23.2 85.5 107.6 48.3 31.6 10.3 78.7 13.8 33.0 59.6 50.0 166.6 65.4 10.9 29.3 40.1 18.4 16.8 70.9 45.4 22.4 24.1 94.9 29.6 18.6 58.9 42.7 86.2 20.2 31.8 16.5 59.3 86.5 26.0 82.2 15.1 37.3 42.6 16.0 10.6 10.8 21.3 13.1 79.0 48.9 51.6 29.3 77.0 108.3 54.9 48.7 17.9 34.8 83.5 TSC22D4 "THG-1, TILZ2" ENSG00000166925 "TSC22 domain family member 4" Q9Y3Q8 7 100463359-100479232 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 601.0;choroid plexus: 224.0" "Cell type enriched" "Detected in all" 4 "Muller glia cells: 778.8" "Cancer enhanced" "Detected in all" "glioma: 118.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 198.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006757 Uncertain Approved Cytosol NA NA 160000 "Cluster 52: Eosinophils - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 24: NB-4 - Immune response" "Cluster 5: Muller glia cells - Visual perception" Cytosol "HPA006757: AB_1080403" "unprognostic (2.34e-2)" "unprognostic (3.06e-2)" "prognostic unfavorable (2.66e-4)" "unprognostic (5.77e-2)" "unprognostic (1.69e-1)" "unprognostic (3.06e-1)" "prognostic unfavorable (9.45e-4)" "unprognostic (9.96e-2)" "unprognostic (1.27e-1)" "unprognostic (1.62e-2)" "unprognostic (2.31e-2)" "unprognostic (3.36e-1)" "unprognostic (1.09e-1)" "unprognostic (1.54e-2)" "unprognostic (3.84e-2)" "unprognostic (7.36e-2)" "unprognostic (3.81e-3)" 37.1 52.7 437.1 33.6 601.0 72.0 36.1 524.6 456.9 43.4 224.0 47.5 23.5 40.5 10.1 73.0 36.8 14.4 59.7 384.9 457.3 64.1 30.0 42.6 40.6 527.5 563.9 44.1 37.3 18.5 52.1 22.7 484.3 55.7 10.7 21.9 97.6 22.2 26.2 58.8 44.4 14.0 485.2 95.2 38.6 36.7 538.9 31.2 34.5 28.7 23.2 37.8 46.8 565.4 42.0 30.8 10.3 33.7 34.2 40.5 19.9 30.5 49.6 28.3 25.8 16.9 25.0 36.8 36.1 24.4 66.0 31.2 12.2 26.7 9.9 65.6 25.2 34.2 34.5 14.6 54.4 44.1 86.3 45.7 24.0 32.4 32.2 33.0 58.3 29.0 75.2 64.2 22.9 74.3 55.6 198.4 14.0 35.7 42.6 89.7 8.1 51.6 23.2 22.3 8.8 25.1 41.4 78.8 65.5 16.7 22.5 63.1 50.2 38.4 39.1 95.0 22.8 40.9 42.6 27.1 35.7 66.4 47.8 9.7 18.7 30.0 19.0 20.2 14.9 11.9 16.3 17.9 12.7 11.8 15.2 16.2 56.1 18.8 20.5 13.3 25.0 18.2 437.1 601.0 524.6 456.9 384.9 457.3 527.5 563.9 484.3 485.2 538.9 565.4 16.7 12.8 8.9 123.4 50.8 32.8 35.9 50.7 37.5 15.4 47.3 61.3 17.7 44.3 32.5 40.5 6.2 30.7 69.3 60.3 137.0 63.5 1.7 14.0 25.5 26.1 33.6 60.6 3.8 33.9 35.3 29.8 21.4 19.9 15.9 36.1 42.1 11.1 79.9 18.5 4.6 32.1 38.7 57.7 67.1 5.2 45.7 56.7 55.2 14.0 77.2 778.8 116.4 50.8 162.6 60.6 52.7 39.9 31.8 59.2 62.8 21.0 13.7 18.2 46.0 16.1 34.5 1.7 5.4 32.8 33.8 79.1 78.2 28.9 31.7 80.3 TSGA10 "CEP4L, CT79" ENSG00000135951 "Testis specific 10" Q9BZW7 2 98997261-99154964 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 51.5" "Cell type enhanced" "Detected in all" "Early spermatids: 458.9;Late spermatids: 294.2;Oligodendrocytes: 144.9;Spermatocytes: 206.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 4.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036879 Approved Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA036879: AB_10671715" "unprognostic (1.71e-3)" "unprognostic (6.68e-2)" "unprognostic (2.97e-1)" "unprognostic (1.12e-1)" "unprognostic (4.95e-2)" "unprognostic (3.69e-2)" "unprognostic (1.04e-2)" "unprognostic (2.52e-2)" "unprognostic (1.98e-2)" "unprognostic (2.39e-1)" "unprognostic (1.15e-5)" "unprognostic (2.32e-1)" "unprognostic (2.82e-6)" "unprognostic (1.06e-2)" "unprognostic (9.91e-3)" "unprognostic (9.79e-2)" "unprognostic (8.37e-4)" 1.1 1.0 1.8 0.6 1.6 0.7 1.4 1.6 1.9 1.3 3.7 0.9 1.0 1.1 1.6 0.6 12.6 1.1 0.2 1.8 1.6 3.0 0.5 1.6 1.0 3.4 3.5 0.5 1.7 1.6 2.5 0.4 2.5 1.0 1.3 2.6 1.1 0.6 0.1 1.9 0.6 0.3 2.7 0.8 1.4 51.5 1.5 1.1 3.1 0.2 0.8 0.6 0.4 3.7 0.8 0.2 1.2 0.5 0.6 0.7 0.9 0.0 0.1 0.3 0.2 0.2 0.8 0.7 0.2 0.0 0.5 0.2 0.2 0.2 0.3 1.0 0.8 0.1 0.0 0.3 0.0 0.5 1.7 0.9 1.0 0.1 0.1 0.7 0.0 0.9 0.0 0.0 0.6 0.2 0.2 0.4 0.1 0.3 0.2 0.3 0.1 0.2 4.2 0.7 1.7 0.2 0.9 0.7 0.2 1.3 0.2 0.3 0.4 0.2 0.4 0.0 0.1 0.6 0.3 0.3 0.3 1.0 0.4 0.1 0.2 0.2 0.6 0.0 0.7 0.7 0.7 0.8 0.0 0.8 1.1 0.7 0.0 1.0 0.0 0.4 0.7 0.3 1.8 1.6 1.6 1.9 1.8 1.6 3.4 3.5 2.5 2.7 1.5 3.7 3.1 3.2 9.2 35.3 13.3 3.6 10.3 8.6 6.2 19.3 13.9 15.4 7.1 17.2 14.5 23.9 29.2 9.7 5.6 4.7 25.4 8.4 458.9 80.6 4.5 4.0 15.5 8.6 73.4 10.5 4.3 5.8 8.6 10.9 5.1 5.3 4.2 7.1 4.6 20.2 57.9 6.7 12.2 3.1 1.4 294.2 11.1 5.1 1.8 23.4 4.5 21.1 15.5 27.6 144.9 4.7 12.2 9.8 8.1 7.8 8.0 12.9 107.9 36.6 6.6 5.7 6.2 206.8 36.6 5.6 4.4 9.3 8.9 5.9 8.4 7.9 TSNARE1 FLJ31164 ENSG00000171045 "T-SNARE domain containing 1" Q96NA8 8 142212080-142403182 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 26.7;Inhibitory neurons: 23.0;Oligodendrocyte precursor cells: 21.1;Oligodendrocytes: 24.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-937: 24.5" "Low region specificity" "Detected in all" HPA074249 Approved Approved Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 50: Non-specific - Ribosome" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA074249: " "unprognostic (2.92e-2)" "unprognostic (1.44e-1)" "unprognostic (3.94e-3)" "unprognostic (1.22e-2)" "unprognostic (1.35e-1)" "unprognostic (1.09e-2)" "unprognostic (1.48e-2)" "unprognostic (3.72e-3)" "unprognostic (1.74e-1)" "unprognostic (1.67e-1)" "unprognostic (6.87e-3)" "unprognostic (1.66e-1)" "unprognostic (6.26e-2)" "unprognostic (1.46e-1)" "unprognostic (2.46e-1)" "unprognostic (1.29e-1)" "prognostic favorable (7.33e-4)" 10.1 9.5 10.8 6.6 10.6 4.2 12.0 5.0 19.0 16.3 4.8 11.3 11.6 13.8 2.9 10.4 15.0 5.9 9.1 9.9 7.3 13.6 10.0 9.9 6.7 12.0 8.4 20.4 28.5 7.0 12.9 3.3 9.2 13.7 2.8 4.0 13.4 6.4 11.0 27.3 12.9 3.8 5.9 12.6 13.3 13.4 8.9 6.2 16.3 4.6 4.4 11.8 12.1 14.1 6.6 6.4 4.2 5.3 3.2 2.9 13.2 1.9 3.1 1.9 1.9 2.1 7.0 3.5 10.7 1.5 3.2 5.9 1.9 6.6 0.8 4.0 6.4 4.2 1.7 7.2 8.5 9.5 9.6 5.6 6.2 0.0 4.3 3.9 2.1 18.4 8.4 0.3 1.3 8.7 8.1 8.8 4.2 6.4 15.8 0.0 2.2 6.2 3.6 8.0 17.5 10.6 8.9 7.1 12.8 2.0 4.7 8.2 5.1 3.1 8.5 5.6 4.3 0.5 2.8 5.6 5.7 24.5 3.2 1.6 0.5 0.1 0.9 2.3 0.6 0.3 0.5 0.2 0.6 0.4 0.2 0.3 0.0 0.5 2.0 0.0 0.6 0.6 10.8 10.6 5.0 19.0 9.9 7.3 12.0 8.4 9.2 5.9 8.9 14.1 1.9 0.0 1.1 12.1 2.3 4.5 2.2 0.8 6.8 2.6 1.8 1.8 4.6 2.8 0.5 1.8 2.1 0.3 1.6 1.6 3.9 1.6 2.4 1.9 1.0 1.5 1.8 2.5 26.7 1.8 1.8 1.5 4.1 1.4 0.0 1.2 1.1 1.3 1.9 0.0 23.0 2.1 0.0 2.6 2.9 5.3 0.9 1.7 3.6 12.2 1.5 3.1 2.1 21.1 24.6 1.6 0.2 1.5 1.6 1.3 1.6 1.4 2.3 1.3 0.0 2.3 1.7 5.0 3.7 3.5 7.5 0.3 3.1 0.7 0.9 1.5 TSPY1 "CT78, TSPY" ENSG00000258992 "Testis specific protein Y-linked 1" Q01534 Y 9466955-9469749 "Disease related genes, Predicted intracellular proteins" "Differentiation, Gonadal differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 74 "testis: 7.3" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "testis cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 366 "U-266/70: 248.7;U-266/84: 249.2" "HPA049384, HPA067289" Supported Approved Cytosol NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" Cytosol "HPA049384: AB_2680738, HPA067289: " "unprognostic (2.91e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 248.7 249.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TSPY10 ENSG00000236424 "Testis specific protein Y-linked 10" P0CW01 Y 9527880-9530682 "Predicted intracellular proteins" "Differentiation, Gonadal differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11 "testis: 1.6" "Cell type enriched" "Detected in some" 10 "Spermatogonia: 10.3" "Cancer enriched" "Detected in single" 13 "testis cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-266/84: 63.8" "HPA049384, HPA067289" Supported Approved Cytosol NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Cytosol "HPA049384: AB_2680738, HPA067289: " "unprognostic (5.36e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 11.8 63.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 10.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TSPY2 TSPYQ1 ENSG00000168757 "Testis specific protein Y-linked 2" A6NKD2 Y 6246223-6249019 "Predicted intracellular proteins" "Differentiation, Gonadal differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 27 "testis: 7.5" "Group enriched" "Detected in some" 34 "Spermatocytes: 7.7;Spermatogonia: 27.0" "Cancer enriched" "Detected in single" 7 "testis cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 656 "U-266/70: 107.3;U-266/84: 119.3" "HPA049384, HPA067289" Supported Approved Cytosol NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Cytosol "HPA049384: AB_2680738, HPA067289: " "unprognostic (3.69e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.3 119.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 27.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TSPY3 CT78 ENSG00000228927 "Testis specific protein Y-linked 3" P0CV98 Y 9398421-9401223 "Predicted intracellular proteins" "Differentiation, Gonadal differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "testis: 3.0" "Cell type enriched" "Detected in some" 5 "Spermatogonia: 5.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 75 "U-266/70: 148.5;U-266/84: 145.3" "HPA049384, HPA067289" Supported Approved Cytosol NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Cytosol "HPA049384: AB_2680738, HPA067289: " "unprognostic (4.19e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 148.5 145.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TSPY4 ENSG00000233803 "Testis specific protein Y-linked 4" P0CV99 Y 9337464-9340284 "Predicted intracellular proteins" "Differentiation, Gonadal differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 138 "testis: 32.7" "Cell type enriched" "Detected in single" 11 "Spermatogonia: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 591 "U-266/70: 1954.4;U-266/84: 2232.7" "HPA049384, HPA067289" Supported Approved Cytosol NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Cytosol "HPA049384: AB_2680738, HPA067289: " 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 32.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 1.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.1 0.0 2.4 1954.4 2232.7 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TSPY8 ENSG00000229549 "Testis specific protein Y-linked 8" P0CW00 Y 9357797-9360599 "Predicted intracellular proteins" "Differentiation, Gonadal differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "testis: 1.3" "Group enriched" "Detected in some" 17 "Spermatocytes: 2.0;Spermatogonia: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 266 "U-266/84: 291.5" "HPA049384, HPA067289" Supported Approved Cytosol NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Cytosol "HPA049384: AB_2680738, HPA067289: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.4 1.0 291.5 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TSPY9P TSPY9 ENSG00000238074 "Testis specific protein Y-linked 9, pseudogene" Y 9487313-9489893 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 50 "testis: 7.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 625 "U-266/70: 678.1;U-266/84: 699.0" "HPA049384, HPA067289" Supported Approved Cytosol NA NA "Cluster 29: U-266 - Adaptive immune response" Cytosol "HPA049384: AB_2680738, HPA067289: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.7 678.1 699.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TTC1 TPR1 ENSG00000113312 "Tetratricopeptide repeat domain 1" Q99614 5 160009113-160065543 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036557, HPA057502" Approved Enhanced Cytosol NA NA 17000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA036557: AB_10670112, HPA057502: AB_2683450" "unprognostic (4.34e-3)" "unprognostic (2.26e-2)" "unprognostic (3.05e-2)" "unprognostic (7.38e-2)" "unprognostic (6.62e-2)" "unprognostic (8.13e-2)" "prognostic unfavorable (1.71e-4)" "unprognostic (8.29e-2)" "unprognostic (2.38e-1)" "unprognostic (5.50e-2)" "unprognostic (2.31e-1)" "unprognostic (2.35e-1)" "unprognostic (1.08e-3)" "unprognostic (2.04e-2)" "unprognostic (1.51e-1)" "unprognostic (4.05e-2)" "unprognostic (6.16e-2)" 37.0 46.5 77.6 35.6 79.7 26.2 39.4 84.2 111.7 31.5 71.2 44.5 27.3 32.2 58.1 37.4 32.2 26.2 59.9 79.4 83.1 49.5 45.5 33.0 47.8 90.6 85.4 32.6 27.4 45.1 29.8 35.5 88.7 33.4 45.4 42.9 39.4 37.2 91.2 34.8 30.9 41.8 80.3 36.6 34.6 33.8 83.8 48.7 35.7 77.0 55.9 35.7 27.6 84.1 83.2 85.1 62.2 104.4 71.9 51.6 70.5 90.8 80.4 97.7 115.6 120.2 94.0 84.5 172.7 78.2 132.9 63.9 83.5 124.7 156.6 157.7 88.4 75.9 63.0 87.3 102.0 127.2 61.2 48.7 81.0 86.5 71.8 71.8 118.8 74.2 73.6 81.7 112.3 65.0 92.8 99.8 70.7 67.3 85.8 88.4 87.0 93.6 124.2 76.8 51.2 57.7 63.1 74.4 175.1 58.3 117.6 121.5 84.4 64.8 55.8 58.5 141.9 58.4 114.8 82.3 89.6 143.3 85.9 109.8 72.8 105.7 57.6 80.9 73.4 92.6 68.3 68.0 73.5 86.0 62.5 69.1 103.0 87.7 80.6 65.4 90.2 113.1 77.6 79.7 84.2 111.7 79.4 83.1 90.6 85.4 88.7 80.3 83.8 84.1 48.6 67.3 50.8 20.9 55.0 47.0 33.6 89.2 28.5 38.4 40.4 47.0 237.0 40.0 67.4 46.0 20.9 108.7 36.0 58.0 162.4 114.2 115.3 62.8 46.5 61.3 35.3 89.2 54.0 106.5 77.9 57.4 23.4 54.8 83.4 41.3 52.1 72.8 90.0 35.3 47.6 51.4 83.4 48.1 34.7 39.9 46.9 52.4 28.4 23.4 70.1 99.1 68.0 43.7 57.0 98.5 54.7 63.9 42.9 37.6 53.7 144.9 89.4 50.2 59.2 55.7 59.2 142.9 101.5 37.8 47.3 99.9 50.8 53.6 53.7 21.9 TTC21B "FAP60, FLA17, FLJ11457, IFT139B, JBTS11, NPHP12, THM1" ENSG00000123607 "Tetratricopeptide repeat domain 21B" Q7Z4L5 2 165857475-165953851 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome, Mental retardation, Nephronophthisis, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 67.8;Excitatory neurons: 81.2;Inhibitory neurons: 85.5;Oligodendrocyte precursor cells: 77.9;Oligodendrocytes: 58.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035495, HPA073293" Supported Approved Cytosol NA No "Cluster 38: Basophils - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA035495: AB_10672866, HPA073293: " "unprognostic (1.63e-2)" "unprognostic (1.17e-1)" "unprognostic (3.10e-1)" "unprognostic (1.60e-2)" "unprognostic (2.96e-1)" "unprognostic (2.51e-1)" "unprognostic (7.09e-3)" "unprognostic (2.81e-2)" "unprognostic (2.98e-2)" "unprognostic (7.57e-2)" "unprognostic (3.52e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (1.36e-4)" "unprognostic (1.32e-1)" "unprognostic (1.55e-1)" "unprognostic (2.37e-2)" "unprognostic (1.84e-2)" 5.5 4.1 3.1 3.1 3.4 2.1 5.3 6.5 4.3 6.8 2.6 5.1 2.6 6.3 2.8 3.0 7.3 2.8 5.2 3.2 3.2 5.2 4.0 4.7 4.1 3.3 3.5 8.0 5.0 4.3 4.6 4.7 3.5 6.1 4.0 7.5 4.6 4.2 9.1 4.7 4.2 4.1 3.2 4.0 4.3 4.4 3.1 5.0 4.3 9.2 3.3 4.7 6.0 3.9 4.1 2.1 11.8 6.2 11.0 7.0 3.6 8.2 5.9 4.9 5.8 4.4 2.5 8.9 3.8 3.2 4.7 5.0 8.2 4.8 6.9 6.4 4.9 6.5 4.4 13.6 6.2 6.7 0.0 4.0 2.9 5.9 5.2 8.4 7.0 5.6 9.6 6.1 9.0 2.4 7.0 7.8 6.9 4.6 6.9 9.5 9.1 3.9 6.2 8.2 9.6 6.9 4.7 1.7 8.6 6.3 2.5 7.2 3.9 12.0 5.1 6.5 5.4 3.5 4.5 5.8 5.2 5.4 7.2 3.2 0.5 0.6 0.8 0.6 1.1 1.2 1.0 0.8 0.9 1.0 1.0 1.3 0.2 1.4 1.0 0.4 1.1 0.5 3.1 3.4 6.5 4.3 3.2 3.2 3.3 3.5 3.5 3.2 3.1 3.9 11.1 3.2 9.8 32.7 12.9 9.2 8.3 5.3 22.8 21.6 7.2 6.9 12.5 4.3 9.4 5.5 33.3 3.8 20.2 4.6 0.0 3.3 2.4 67.8 15.3 8.2 7.2 13.7 81.2 1.8 4.6 11.3 11.2 21.6 6.3 12.8 10.8 8.4 13.1 15.2 85.5 7.7 6.1 8.1 4.9 3.2 10.5 7.2 10.6 44.0 5.7 9.9 9.2 77.9 58.9 1.1 6.5 12.8 14.5 6.3 4.0 7.2 34.7 22.7 6.6 15.9 10.7 7.1 12.1 8.5 3.8 2.9 12.5 8.5 5.8 4.7 TTC23 "FLJ12572, HCC-8" ENSG00000103852 "Tetratricopeptide repeat domain 23" Q5W5X9 15 99136323-99251223 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 27.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.8" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039806, HPA040369" Uncertain Approved Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 38: EFO-21 - Unknown function" "Cluster 52: Non-specific - Transcription" Cytosol "HPA039806: AB_10793921, HPA040369: AB_10795381" "prognostic favorable (3.17e-4)" "unprognostic (5.41e-2)" "unprognostic (1.45e-1)" "prognostic favorable (1.07e-4)" "unprognostic (1.40e-2)" "unprognostic (6.53e-2)" "unprognostic (9.25e-3)" "unprognostic (2.56e-1)" "unprognostic (6.18e-2)" "unprognostic (1.76e-3)" "unprognostic (1.88e-1)" "unprognostic (3.24e-1)" "unprognostic (3.21e-2)" "unprognostic (1.11e-2)" "unprognostic (4.31e-1)" "unprognostic (7.99e-2)" "unprognostic (1.23e-1)" 8.3 10.1 5.3 4.3 6.6 1.1 8.0 5.1 6.3 11.6 6.6 17.1 3.5 11.2 6.9 9.8 10.0 8.8 10.6 4.5 6.2 8.9 8.1 6.6 3.1 6.7 5.8 14.9 8.0 8.9 5.3 9.4 6.5 10.7 7.8 7.2 6.7 9.2 8.1 8.4 6.8 10.0 5.7 5.2 9.1 13.0 6.0 3.7 12.7 7.6 3.3 13.2 10.1 8.1 9.9 9.8 15.3 17.8 18.0 20.2 6.4 12.0 14.8 12.6 14.2 8.8 17.0 2.4 23.7 13.7 11.4 19.0 5.0 12.0 13.7 3.3 16.3 10.7 17.1 7.0 10.4 2.4 0.7 14.5 10.5 9.9 9.5 13.7 21.6 4.8 8.3 1.4 11.8 6.0 8.6 2.7 8.4 2.7 7.0 2.7 19.9 3.8 10.0 13.2 6.7 3.0 15.8 6.4 14.7 15.4 10.7 10.9 14.3 16.0 9.4 10.7 15.5 8.1 12.4 3.3 14.3 0.8 9.6 1.8 0.1 0.1 0.0 0.3 0.1 0.1 0.1 0.1 0.7 0.1 0.0 0.0 0.5 0.5 0.1 0.5 0.1 0.0 5.3 6.6 5.1 6.3 4.5 6.2 6.7 5.8 6.5 5.7 6.0 8.1 5.9 3.2 7.0 27.1 0.6 2.4 4.6 4.4 4.6 1.7 4.6 4.3 9.5 4.3 5.2 5.5 0.0 4.6 0.1 4.3 5.9 6.0 12.5 3.3 10.6 7.0 0.0 0.8 3.3 6.2 4.6 7.4 10.2 4.5 1.3 13.5 9.3 5.3 4.0 8.4 3.5 5.7 6.1 3.8 1.7 8.5 9.0 2.5 1.8 15.9 0.6 11.5 0.0 6.6 13.2 3.9 2.6 10.1 0.1 3.1 3.8 5.5 4.0 5.4 6.6 6.5 5.5 18.0 9.2 7.9 4.0 1.9 0.4 10.9 6.7 2.6 TTC38 FLJ20699 ENSG00000075234 "Tetratricopeptide repeat domain 38" Q5R3I4 22 46267961-46294008 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 233.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 134.2;NK-cells: 182.3;Proximal enterocytes: 144.5;Proximal tubular cells: 149.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 90.5" "Group enriched" "Detected in all" 4 "granulocytes: 29.9;NK-cells: 38.0;T-cells: 90.5" "Cell line enhanced" "Detected in many" "Hep G2: 76.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029302, HPA075893" Approved Approved Cytosol NA NA 170000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA029302: AB_10601704, HPA075893: " "unprognostic (7.78e-2)" "unprognostic (5.85e-2)" "unprognostic (4.92e-3)" "prognostic favorable (3.21e-6)" "unprognostic (8.34e-2)" "unprognostic (6.38e-2)" "unprognostic (8.72e-2)" "unprognostic (3.62e-2)" "unprognostic (9.45e-2)" "unprognostic (7.22e-2)" "unprognostic (1.12e-1)" "unprognostic (5.66e-2)" "unprognostic (7.34e-3)" "unprognostic (9.02e-2)" "unprognostic (4.12e-1)" "unprognostic (4.97e-1)" "unprognostic (8.33e-2)" 24.7 23.6 9.5 10.2 11.6 46.9 25.7 10.3 10.7 16.8 12.8 42.1 79.4 13.8 6.4 12.5 17.2 15.5 23.2 9.7 11.0 64.4 233.6 15.6 10.7 13.3 12.3 26.0 35.5 7.6 13.2 7.8 11.9 23.6 31.9 4.7 27.0 7.3 20.6 12.2 80.9 10.3 10.3 22.8 29.1 6.8 12.2 2.5 15.2 12.3 5.9 16.9 13.5 11.3 12.0 13.2 16.4 34.5 15.2 13.1 15.7 17.2 11.5 18.7 14.6 21.8 8.5 0.1 10.8 17.9 7.4 10.8 16.8 13.9 6.8 27.0 36.9 15.6 28.4 76.0 21.0 9.0 59.8 22.6 7.3 8.5 9.7 12.9 15.9 0.2 11.9 19.4 12.2 12.1 0.3 28.2 12.5 22.6 13.1 0.0 8.0 8.0 12.6 13.8 2.9 22.8 23.7 16.3 13.3 7.5 26.1 18.0 18.5 13.0 14.1 10.3 11.0 14.7 9.2 1.7 8.8 13.7 13.8 29.9 11.9 22.5 90.5 11.4 9.7 2.3 8.5 41.0 10.8 1.7 3.5 36.9 7.6 38.0 8.7 4.3 4.5 42.5 9.5 11.6 10.3 10.7 9.7 11.0 13.3 12.3 11.9 10.3 12.2 11.3 9.2 0.0 7.5 13.7 6.5 3.3 5.9 4.3 3.4 2.6 10.2 6.7 9.2 38.6 4.3 9.2 6.2 10.4 69.1 69.0 23.5 10.4 0.3 7.4 9.6 8.9 20.9 10.5 0.3 10.2 9.3 7.5 11.7 6.9 17.2 13.3 9.7 134.2 13.4 5.0 1.8 37.8 4.1 14.9 4.3 0.9 7.5 9.6 5.4 9.4 12.8 9.3 182.3 5.5 5.6 9.7 51.6 13.9 16.2 8.6 144.5 149.6 5.3 5.4 6.6 7.4 5.9 1.8 3.7 5.3 8.2 6.4 29.2 22.7 51.7 4.6 TTF2 "HuF2, ZGRF6" ENSG00000116830 "Transcription termination factor 2" Q9UNY4 1 117060326-117107453 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation, Transcription termination" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA005776, HPA070762" Approved Supported Cytosol NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA005776: AB_1080416, HPA070762: AB_2686307" "unprognostic (1.82e-1)" "unprognostic (2.18e-1)" "unprognostic (3.29e-3)" "unprognostic (2.01e-3)" "unprognostic (4.90e-2)" "unprognostic (3.41e-3)" "unprognostic (5.27e-4)" "unprognostic (7.96e-2)" "unprognostic (1.92e-2)" "unprognostic (3.33e-1)" "unprognostic (4.64e-2)" "unprognostic (9.52e-3)" "unprognostic (7.34e-3)" "unprognostic (1.48e-3)" "unprognostic (7.73e-2)" "unprognostic (3.50e-1)" "unprognostic (3.65e-2)" 3.8 4.7 2.6 6.4 3.9 5.4 4.2 2.8 3.7 3.3 3.6 5.0 4.3 3.0 1.7 5.2 2.6 2.8 3.1 2.4 2.8 2.6 1.4 2.6 7.3 5.4 3.5 2.7 3.5 3.9 2.3 2.7 3.6 2.5 5.4 2.5 3.3 2.5 4.7 4.9 4.0 4.0 3.0 4.3 3.9 4.2 3.8 8.9 3.6 2.3 7.9 3.3 3.6 4.7 27.7 10.0 19.8 28.0 7.7 6.7 24.6 14.5 6.7 20.8 18.3 14.1 4.8 33.4 21.8 9.6 23.2 28.1 35.2 18.7 32.0 25.9 24.8 28.5 19.5 18.2 5.5 42.1 31.5 7.7 7.0 15.4 28.4 5.2 14.4 26.0 22.3 29.6 15.9 42.4 28.1 26.0 30.9 26.3 20.0 40.0 72.7 14.6 12.7 12.4 16.8 7.0 21.7 21.4 8.4 14.9 11.7 17.0 14.6 13.1 27.6 31.0 31.8 13.5 12.5 40.6 8.8 31.2 53.7 0.9 2.3 1.5 1.2 2.8 1.2 1.5 1.4 2.0 2.6 1.5 1.4 1.7 0.4 2.6 1.6 1.4 2.7 1.0 2.6 3.9 2.8 3.7 2.4 2.8 5.4 3.5 3.6 3.0 3.8 4.7 4.4 6.4 6.4 6.8 13.4 13.3 17.1 8.5 12.0 5.7 7.6 6.3 7.3 5.7 7.3 12.9 8.4 9.7 8.9 10.6 5.9 6.6 6.9 8.9 15.6 6.9 4.9 30.3 8.1 8.0 7.6 11.0 8.6 12.3 9.5 24.7 5.7 3.0 11.4 11.8 4.7 8.3 0.0 8.6 12.1 7.0 6.5 14.5 7.2 10.3 22.1 3.3 14.4 2.5 13.5 9.3 5.1 4.1 16.0 22.7 6.2 3.8 5.1 7.2 0.0 18.4 8.5 9.2 12.4 19.4 14.3 3.8 12.3 12.2 13.5 17.9 TULP2 "CT65, TUBL2" ENSG00000104804 "TUB like protein 2" O00295 19 48880967-48898744 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 37.6" "Group enriched" "Detected in some" 16 "Early spermatids: 281.1;Late spermatids: 233.0" "Cancer enriched" "Detected in single" 8 "testis cancer: 1.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 10 "plasmacytoid DC: 3.0" "Lineage enriched" "Detected in single" 10 "dendritic cells: 3.0" "Cell line enhanced" "Detected in some" "BEWO: 2.6;U-266/70: 3.0;U-266/84: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA075828 Approved Cytosol "Secreted in male reproductive system" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 78: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol "HPA075828: " "unprognostic (9.97e-2)" "unprognostic (5.55e-3)" "unprognostic (1.15e-1)" "unprognostic (9.39e-2)" "unprognostic (1.69e-4)" "unprognostic (6.79e-4)" "unprognostic (1.07e-2)" "unprognostic (2.57e-1)" "unprognostic (5.94e-3)" "unprognostic (1.08e-2)" "unprognostic (9.82e-2)" "unprognostic (1.33e-1)" "unprognostic (4.59e-4)" "unprognostic (6.37e-2)" "unprognostic (1.63e-1)" "unprognostic (1.08e-1)" "unprognostic (1.97e-1)" 0.2 0.5 1.9 0.1 2.3 5.2 0.5 3.5 8.4 0.3 1.0 0.3 0.0 1.0 0.1 0.8 0.8 0.8 0.5 2.3 1.9 0.2 0.1 0.5 0.2 1.6 1.4 1.4 0.1 0.1 0.1 0.1 2.0 0.7 0.2 0.5 0.1 0.2 0.5 0.1 0.5 0.4 1.4 1.4 0.4 37.6 2.1 0.1 0.3 0.1 0.3 0.3 0.2 1.7 0.0 0.0 0.0 0.0 0.0 0.1 2.6 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.7 0.9 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.4 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.3 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.0 3.4 0.1 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 3.0 0.0 0.0 1.9 2.3 3.5 8.4 2.3 1.9 1.6 1.4 2.0 1.4 2.1 1.7 0.2 0.0 0.5 0.3 0.8 0.3 0.1 0.0 0.0 0.0 0.1 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 281.1 0.8 2.7 1.0 0.0 0.0 0.9 0.0 0.1 0.6 0.0 2.2 2.5 0.1 0.0 0.2 0.2 0.0 0.6 0.2 0.0 0.3 0.7 233.0 4.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 6.4 1.4 15.4 1.4 0.4 0.4 0.0 0.6 0.1 0.0 0.0 TWF1 "A6, PTK9" ENSG00000151239 "Twinfilin actin binding protein 1" Q12792 12 43793723-43806328 "Disease related genes, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018116 Approved Supported Cytosol NA NA 75000 "Cluster 15: NK-cells - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "HPA018116: AB_1855899" "unprognostic (3.06e-1)" "unprognostic (1.95e-2)" "prognostic favorable (8.29e-4)" "unprognostic (7.39e-3)" "unprognostic (2.35e-2)" "unprognostic (1.11e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (5.19e-2)" "unprognostic (1.13e-2)" "unprognostic (7.30e-2)" "unprognostic (3.11e-3)" "unprognostic (2.51e-1)" "unprognostic (8.48e-2)" "unprognostic (1.03e-1)" "unprognostic (2.19e-1)" "unprognostic (2.95e-1)" "unprognostic (2.62e-1)" 45.2 40.2 27.9 39.0 33.0 46.2 49.4 30.6 38.9 54.8 27.2 65.9 68.7 39.9 48.5 93.8 45.3 48.7 13.1 26.5 32.5 51.2 53.9 24.9 30.5 32.5 30.9 27.1 39.0 39.9 23.9 35.0 32.6 46.0 65.7 32.5 42.5 73.5 5.8 36.7 67.8 46.6 31.8 20.2 46.1 20.1 30.8 24.4 73.1 11.7 34.2 74.6 38.0 37.2 121.3 88.5 45.1 55.5 115.8 132.5 109.3 165.3 136.1 131.7 99.2 143.3 165.2 32.5 150.0 159.6 77.3 79.8 62.6 118.2 186.1 11.3 72.5 30.2 68.6 67.7 93.9 35.0 37.6 91.0 94.4 136.8 152.0 167.5 117.0 16.1 33.4 35.9 207.4 64.8 16.8 24.1 27.5 0.0 142.7 14.1 51.1 36.8 175.9 149.1 33.3 50.0 138.2 123.7 121.7 62.8 116.2 34.4 113.0 161.5 107.1 130.8 139.8 31.1 32.9 44.4 148.8 89.0 62.6 10.2 2.6 5.7 5.1 4.1 5.9 6.1 6.0 6.6 4.1 3.0 5.9 6.7 4.4 12.1 4.4 2.7 6.6 3.2 27.9 33.0 30.6 38.9 26.5 32.5 32.5 30.9 32.6 31.8 30.8 37.2 40.7 12.8 33.8 6.2 24.7 41.7 33.3 32.6 42.1 22.7 43.9 30.6 6.0 30.0 40.3 35.0 20.9 41.5 36.2 92.8 41.1 50.9 20.6 70.9 40.3 32.0 44.9 7.8 10.1 79.7 58.0 32.4 53.0 53.6 5.1 27.7 24.3 28.7 26.9 20.2 10.3 45.2 48.8 30.0 20.9 10.8 26.8 24.7 35.6 8.4 17.7 33.5 14.4 10.1 15.7 74.9 77.4 32.0 34.0 57.5 66.3 68.7 53.5 32.9 26.3 25.4 41.7 11.7 22.1 95.0 51.1 85.0 25.8 39.6 61.8 74.9 TXLNG "CXorf15, FIAT, FLJ11209, LSR5, MGC126621, MGC126625, TXLNGX" ENSG00000086712 "Taxilin gamma" Q9NUQ3 X 16786432-16844519 "Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000297, HPA000841" Approved Approved Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "HPA000297: AB_1078590, HPA000841: AB_1078589" "unprognostic (2.48e-2)" "unprognostic (1.12e-2)" "unprognostic (1.54e-1)" "unprognostic (1.27e-3)" "unprognostic (4.78e-2)" "unprognostic (4.15e-2)" "prognostic unfavorable (6.33e-6)" "unprognostic (2.61e-2)" "unprognostic (5.27e-3)" "unprognostic (6.96e-2)" "unprognostic (3.61e-2)" "unprognostic (1.40e-2)" "unprognostic (1.58e-3)" "unprognostic (2.04e-2)" "unprognostic (2.22e-1)" "unprognostic (8.62e-2)" "unprognostic (6.00e-3)" 14.4 15.9 4.6 8.0 5.3 14.0 10.1 7.8 6.3 6.9 6.7 6.3 8.3 9.8 6.6 6.1 9.1 6.3 5.7 4.1 5.6 7.5 8.0 7.7 12.6 3.9 4.6 16.5 8.5 11.6 6.9 5.8 4.1 6.5 6.0 14.6 7.0 8.7 5.9 6.1 6.5 7.5 4.0 7.7 6.8 6.0 4.6 9.2 10.4 6.0 11.5 7.9 4.6 6.4 27.7 16.9 15.9 28.3 28.4 15.5 8.4 10.8 10.4 12.1 11.8 23.7 16.1 57.6 26.7 6.1 34.8 17.5 54.9 35.4 21.6 17.7 66.7 20.7 23.5 15.3 12.1 31.1 14.2 9.2 17.1 28.2 50.6 16.4 15.5 23.4 40.3 16.6 9.5 16.5 28.6 17.9 47.6 18.3 19.4 19.5 21.7 47.7 9.7 13.6 25.8 18.7 25.0 23.6 19.8 27.1 28.7 12.7 7.6 7.6 10.0 26.9 18.9 17.4 28.4 57.6 9.6 20.1 7.8 0.6 1.9 1.0 3.1 1.5 4.0 3.7 3.4 3.7 2.1 4.0 4.0 4.4 0.7 2.9 1.7 2.1 3.8 2.1 4.6 5.3 7.8 6.3 4.1 5.6 3.9 4.6 4.1 4.0 4.6 6.4 26.3 16.0 24.8 17.6 32.0 41.0 60.2 13.6 23.3 35.9 27.0 29.1 13.3 17.2 23.3 9.2 6.2 14.2 37.7 9.0 21.5 19.3 4.4 33.5 27.3 15.6 14.4 19.8 32.5 16.7 13.2 35.8 9.7 27.2 13.3 13.1 13.2 16.1 9.0 28.6 39.7 15.0 8.2 7.7 11.1 2.2 27.1 12.2 17.8 11.2 9.0 17.7 12.3 16.1 28.3 15.6 7.7 21.1 17.0 43.6 12.3 20.5 16.3 23.0 6.6 42.3 25.8 17.1 37.7 19.1 34.8 21.9 32.9 16.3 16.2 33.0 TXNDC9 APACD ENSG00000115514 "Thioredoxin domain containing 9" O14530 2 99318982-99340702 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031844, HPA031845, HPA031846" Approved Enhanced Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA031844: AB_10600838, HPA031845: AB_10670968, HPA031846: AB_10669916" "unprognostic (3.63e-3)" "unprognostic (4.26e-2)" "unprognostic (7.28e-2)" "unprognostic (3.12e-2)" "unprognostic (1.32e-1)" "prognostic unfavorable (4.31e-4)" "prognostic unfavorable (9.63e-7)" "unprognostic (2.06e-2)" "unprognostic (9.09e-2)" "unprognostic (1.42e-1)" "unprognostic (1.99e-1)" "unprognostic (1.37e-1)" "unprognostic (2.32e-1)" "unprognostic (2.47e-3)" "unprognostic (2.03e-1)" "unprognostic (1.14e-1)" "unprognostic (1.29e-1)" 18.7 17.9 10.0 21.3 10.8 17.5 28.7 11.0 13.2 19.3 10.4 24.6 18.4 16.6 25.9 26.1 18.1 18.6 28.6 10.8 11.7 28.8 27.2 20.1 29.2 11.6 11.5 10.7 10.9 15.4 11.3 23.5 11.9 19.6 26.3 11.0 15.1 16.1 18.2 19.0 17.6 24.4 11.8 18.6 18.5 17.8 10.9 26.1 24.8 16.2 34.0 24.9 14.1 12.5 78.3 27.6 55.0 27.7 55.8 57.8 65.8 83.1 79.5 88.5 85.0 71.1 55.5 58.0 66.9 72.6 77.0 52.7 55.2 88.2 102.6 44.0 53.5 60.4 34.5 77.0 54.2 71.8 44.2 53.0 76.7 74.3 53.8 46.1 101.9 32.1 73.0 51.1 103.7 41.5 43.4 63.6 43.4 46.4 68.7 32.5 53.0 56.4 123.9 62.6 37.1 31.5 41.7 56.2 93.7 69.8 64.3 60.9 69.4 65.1 62.7 40.6 62.6 21.2 37.1 65.6 51.9 76.8 58.6 110.6 54.1 61.1 56.7 60.5 70.2 69.1 66.6 64.4 60.3 57.6 61.9 62.5 53.5 77.7 82.6 60.9 91.2 87.0 10.0 10.8 11.0 13.2 10.8 11.7 11.6 11.5 11.9 11.8 10.9 12.5 46.6 9.6 13.4 8.8 33.4 35.2 29.7 137.1 25.0 11.3 21.5 26.3 27.6 25.8 67.0 36.8 8.4 75.7 31.3 26.2 84.1 79.8 75.7 37.3 29.9 46.2 20.9 47.8 13.3 69.4 82.5 29.2 22.4 25.5 17.7 21.0 38.2 24.4 56.9 13.5 12.8 25.7 91.6 25.4 31.3 21.1 27.7 30.2 26.6 4.7 55.5 26.9 44.3 12.5 16.7 84.5 21.6 23.3 31.8 24.0 21.9 121.5 72.8 19.8 26.3 17.8 89.3 52.8 42.7 29.4 38.9 81.3 35.1 40.1 26.6 21.9 TXNL1 "TRP32, Txl, TXNL" ENSG00000091164 "Thioredoxin like 1" O43396 18 56597209-56651600 "Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002828, HPA002829, CAB016446" Supported Supported Enhanced Cytosol NA Yes 1100000 "Cluster 34: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB016446: , HPA002828: AB_1858358, HPA002829: AB_1858359" "unprognostic (2.05e-1)" "unprognostic (2.97e-1)" "unprognostic (3.38e-3)" "unprognostic (4.54e-2)" "unprognostic (2.51e-1)" "unprognostic (1.78e-1)" "prognostic unfavorable (9.62e-6)" "unprognostic (1.83e-1)" "unprognostic (1.03e-2)" "prognostic favorable (6.26e-5)" "unprognostic (1.44e-1)" "unprognostic (2.79e-1)" "unprognostic (3.29e-3)" "unprognostic (1.24e-1)" "unprognostic (1.26e-1)" "unprognostic (2.62e-1)" "unprognostic (1.51e-1)" 38.3 55.9 45.4 38.6 47.5 83.0 49.1 49.1 63.6 42.5 40.1 41.7 42.1 38.3 66.9 54.2 35.2 40.0 80.0 50.0 50.9 51.7 80.7 30.6 41.2 47.7 47.2 47.1 62.2 51.4 38.2 48.1 49.5 40.5 43.4 77.9 48.5 39.3 149.0 36.5 40.6 43.4 46.2 32.2 46.7 41.9 47.5 48.0 197.9 146.8 49.9 51.8 35.1 54.0 77.7 74.8 99.2 102.8 83.2 121.6 70.2 90.2 91.8 113.4 95.4 67.0 74.2 83.4 78.1 98.4 82.3 93.7 94.4 81.3 116.9 85.7 43.1 114.9 58.3 127.1 98.3 168.9 71.7 92.9 82.4 107.4 97.4 118.8 93.0 62.9 85.5 136.0 116.0 74.4 98.1 109.8 71.9 53.5 79.6 78.2 66.8 145.9 133.0 118.6 81.6 74.5 51.3 70.9 88.1 78.3 77.5 89.1 74.3 118.7 62.9 41.9 89.5 130.8 151.1 130.5 77.2 127.0 89.1 98.5 63.1 48.3 26.9 55.8 37.2 38.9 33.0 35.8 54.8 35.4 32.0 32.9 48.3 43.3 54.9 47.0 42.9 61.5 45.4 47.5 49.1 63.6 50.0 50.9 47.7 47.2 49.5 46.2 47.5 54.0 89.7 57.7 45.9 25.5 80.0 134.3 123.1 177.1 75.7 82.7 89.3 110.4 110.1 67.2 108.3 29.5 139.7 242.3 82.7 72.2 109.5 150.5 246.9 88.0 90.0 84.2 75.9 153.8 43.8 128.3 130.9 86.1 52.0 90.3 53.2 167.5 52.8 78.0 150.1 57.2 43.6 111.6 77.3 97.3 97.0 294.1 77.6 90.5 65.8 15.9 121.8 86.0 78.2 26.2 55.6 139.5 83.7 83.8 88.9 121.2 110.0 144.7 75.1 97.1 65.7 73.0 167.1 204.1 108.0 93.9 126.0 358.6 72.4 171.0 109.7 123.1 TYK2 JTK1 ENSG00000105397 "Tyrosine kinase 2" P29597 19 10350529-10380572 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 52.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 206.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005157 Uncertain Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "HPA005157: AB_1858480" "unprognostic (1.60e-2)" "unprognostic (6.12e-3)" "unprognostic (3.67e-2)" "prognostic favorable (9.62e-4)" "unprognostic (7.61e-2)" "prognostic favorable (1.05e-5)" "unprognostic (1.20e-2)" "unprognostic (6.16e-3)" "unprognostic (4.93e-2)" "unprognostic (1.90e-2)" "prognostic favorable (1.02e-4)" "unprognostic (1.24e-2)" "prognostic unfavorable (4.43e-4)" "unprognostic (2.10e-3)" "unprognostic (1.78e-1)" "unprognostic (4.19e-1)" "prognostic favorable (4.16e-4)" 53.0 60.5 69.9 37.0 71.9 82.6 52.5 70.7 82.3 55.8 72.2 51.5 29.4 44.8 22.6 46.2 49.0 26.2 65.0 69.6 68.8 77.3 111.2 72.6 51.5 75.1 71.4 56.4 65.1 28.6 66.2 20.1 71.5 64.5 25.7 25.2 50.8 20.6 41.3 51.1 73.9 23.5 70.2 140.8 54.6 16.6 71.8 54.4 60.2 33.7 51.8 49.3 46.0 76.4 29.1 41.1 24.1 38.0 31.9 44.2 23.5 38.9 39.1 48.1 52.2 31.5 18.7 44.5 44.5 43.4 32.8 28.4 29.4 45.5 24.2 78.0 45.5 81.4 90.5 80.2 49.4 34.4 89.4 43.2 31.3 54.5 32.2 29.9 46.5 56.6 35.0 116.1 42.3 90.1 50.7 206.9 7.7 28.4 71.8 49.9 21.1 45.1 40.0 90.1 22.4 28.0 37.6 38.6 28.1 18.4 21.5 57.2 41.1 61.7 22.7 74.1 45.9 97.2 81.4 40.2 32.4 70.8 36.6 9.8 20.8 27.2 12.8 15.2 7.9 7.5 7.6 11.6 23.5 8.0 5.0 7.1 33.0 8.6 15.7 13.0 10.1 13.0 69.9 71.9 70.7 82.3 69.6 68.8 75.1 71.4 71.5 70.2 71.8 76.4 18.6 12.8 17.9 13.1 17.5 6.6 5.4 7.6 13.1 9.2 10.3 11.0 25.7 11.5 11.1 9.2 4.2 7.0 23.2 14.6 52.8 7.6 2.1 10.2 12.6 12.8 4.8 8.6 10.4 11.1 9.7 11.1 27.0 12.0 19.6 17.1 15.4 27.1 14.6 0.0 9.2 8.7 8.2 28.2 14.6 8.8 7.5 30.8 16.0 12.2 25.3 8.7 17.5 11.1 11.1 11.8 12.9 9.8 19.5 5.9 12.1 29.0 11.2 11.0 0.0 10.5 12.6 1.5 4.5 8.8 7.2 6.7 19.4 13.6 11.1 6.3 UBAC2 "FLJ30548, PHGDHL1, RP11-178C10.1" ENSG00000134882 "UBA domain containing 2" Q8NBM4 13 99200774-99386504 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013448 Approved Approved Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA013448: AB_1855301" "unprognostic (7.04e-2)" "unprognostic (1.19e-1)" "unprognostic (2.43e-1)" "unprognostic (7.30e-3)" "unprognostic (2.23e-1)" "unprognostic (2.79e-3)" "unprognostic (9.48e-3)" "unprognostic (6.50e-3)" "unprognostic (1.58e-1)" "unprognostic (6.95e-2)" "prognostic unfavorable (1.73e-4)" "unprognostic (6.44e-2)" "unprognostic (6.13e-3)" "unprognostic (3.33e-2)" "unprognostic (1.16e-1)" "unprognostic (6.08e-2)" "unprognostic (3.26e-2)" 15.3 13.3 9.0 18.2 9.3 19.6 20.0 7.3 9.2 21.3 9.9 21.5 30.7 19.9 17.9 28.6 27.6 22.6 27.3 10.1 8.4 21.9 27.7 16.9 25.4 10.9 9.6 19.1 17.4 30.0 2.7 29.4 8.8 18.4 22.9 7.6 25.8 17.3 39.0 30.6 23.3 19.7 11.6 20.8 17.7 26.2 12.6 29.3 30.0 38.9 27.3 23.9 8.6 8.8 51.8 26.8 22.4 33.9 52.2 62.8 56.3 25.9 73.3 40.3 36.4 29.2 108.7 19.9 43.8 34.8 27.0 49.2 28.8 41.1 22.0 33.8 33.7 37.2 16.9 22.5 48.7 48.2 28.1 45.9 54.9 24.6 71.0 54.6 38.8 39.6 31.1 13.3 31.6 14.3 32.1 15.3 32.6 104.0 27.0 27.6 24.9 15.2 32.7 29.6 25.2 40.3 21.0 67.8 41.4 39.4 41.5 148.7 30.3 21.9 19.0 20.1 29.5 16.3 12.0 6.6 42.9 71.9 38.3 64.6 53.7 41.9 61.3 57.3 87.3 48.1 53.8 62.6 46.2 55.2 73.6 74.5 48.8 84.6 57.5 57.3 40.2 88.1 9.0 9.3 7.3 9.2 10.1 8.4 10.9 9.6 8.8 11.6 12.6 8.8 28.7 6.4 19.1 58.8 45.3 27.1 26.0 41.7 40.5 27.3 31.2 24.3 23.8 21.5 29.4 23.9 27.1 111.6 48.5 37.3 23.5 44.1 26.0 24.5 21.7 26.4 8.4 31.3 110.9 34.9 84.6 31.6 19.4 21.9 22.2 34.3 17.9 29.1 48.5 32.0 103.0 30.1 40.7 39.1 121.4 22.0 35.1 88.4 30.2 81.5 35.7 48.8 69.0 82.0 73.3 29.0 32.6 50.8 11.7 48.7 48.0 22.6 31.6 21.2 32.9 24.7 32.1 66.2 35.1 31.7 33.1 132.4 66.0 54.4 39.1 34.4 UBAP2 "bA176F3.5, FLJ22435, KIAA1491" ENSG00000137073 "Ubiquitin associated protein 2" Q5T6F2 9 33921693-34048949 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021684 Approved Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 24: NB-4 - Immune response" "Cluster 52: Non-specific - Transcription" Cytosol "HPA021684: AB_2211887" "unprognostic (2.71e-1)" "unprognostic (1.99e-1)" "unprognostic (1.17e-1)" "unprognostic (1.61e-2)" "unprognostic (1.69e-1)" "unprognostic (5.18e-2)" "prognostic unfavorable (3.45e-6)" "unprognostic (1.21e-1)" "unprognostic (4.64e-2)" "prognostic favorable (8.59e-4)" "unprognostic (1.75e-1)" "unprognostic (9.76e-3)" "prognostic favorable (1.95e-4)" "unprognostic (8.06e-2)" "unprognostic (2.39e-1)" "unprognostic (2.95e-1)" "unprognostic (8.77e-2)" 12.2 25.7 12.5 8.2 12.9 17.2 12.8 17.3 13.4 15.5 5.3 13.8 8.7 13.0 8.8 19.1 11.4 6.6 15.3 9.5 13.7 14.9 11.1 13.2 10.4 9.4 9.5 15.2 15.4 9.3 11.0 11.8 9.7 14.3 12.1 9.9 13.1 6.7 37.8 22.2 10.8 10.3 6.8 10.9 14.0 32.5 13.6 13.9 15.8 20.5 12.1 12.5 15.2 12.9 40.5 36.5 25.9 32.9 25.2 22.0 31.2 31.8 19.6 32.1 31.0 49.9 21.0 46.8 9.8 26.7 24.7 23.1 43.9 34.9 35.5 34.8 21.5 26.2 47.2 55.0 20.5 59.6 40.3 20.4 28.8 40.8 28.2 16.7 26.3 28.3 36.5 37.6 29.4 26.9 44.6 100.4 27.7 22.6 28.5 34.1 16.0 29.9 31.2 30.1 26.5 18.4 37.6 30.3 9.4 25.8 26.9 26.3 30.9 19.0 25.5 22.8 35.7 14.5 32.3 49.3 20.9 22.5 48.3 1.6 2.7 3.0 2.2 3.1 4.7 2.7 2.7 3.2 3.1 1.4 2.4 3.3 1.6 4.5 7.2 4.1 3.3 2.3 12.5 12.9 17.3 13.4 9.5 13.7 9.4 9.5 9.7 6.8 13.6 12.9 23.8 54.5 23.1 56.8 15.0 28.2 23.8 21.0 27.3 28.7 25.3 26.2 59.9 8.6 32.4 12.9 60.5 44.4 24.7 28.1 3.9 20.0 102.8 52.5 30.3 28.6 25.1 20.8 46.8 19.8 36.3 23.7 32.6 68.8 14.5 36.2 11.7 14.0 16.6 16.8 48.3 30.4 14.2 17.0 21.4 85.0 30.4 17.1 26.6 33.7 19.0 12.5 16.5 50.8 46.3 27.0 26.8 24.5 28.4 24.9 12.3 15.9 24.1 27.0 26.3 27.4 22.6 81.0 70.4 25.9 31.1 72.9 22.3 68.4 29.6 23.7 UBE2F NCE2 ENSG00000184182 "Ubiquitin conjugating enzyme E2 F (putative)" Q969M7 2 237966827-238042782 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 282.2;monocytes: 215.5;NK-cells: 193.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA037444 Approved Approved Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "HPA037444: AB_10672491" "unprognostic (1.73e-1)" "unprognostic (1.65e-1)" "unprognostic (3.80e-2)" "unprognostic (6.92e-3)" "unprognostic (3.39e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (2.72e-4)" "unprognostic (3.43e-3)" "unprognostic (6.64e-2)" "unprognostic (3.87e-1)" "unprognostic (1.69e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (1.59e-7)" "unprognostic (2.04e-2)" "unprognostic (6.39e-2)" "unprognostic (3.60e-2)" "unprognostic (2.51e-1)" 26.7 29.7 33.0 25.5 33.7 41.8 22.8 35.9 40.6 27.7 32.5 29.6 24.7 23.1 53.0 43.1 18.8 28.7 56.7 33.4 38.0 28.2 44.2 22.6 32.1 37.5 37.7 12.6 70.5 41.8 21.0 39.9 38.7 25.4 33.7 16.0 25.2 30.3 60.7 18.8 26.9 35.6 35.5 23.7 26.5 26.0 36.1 34.5 35.4 69.1 33.1 40.7 23.5 38.3 42.9 23.9 53.6 55.1 69.2 83.0 74.8 38.9 55.5 43.3 44.4 26.0 26.4 22.0 13.7 88.7 93.7 35.1 62.3 84.9 67.9 33.7 22.7 31.6 28.5 86.6 86.2 13.1 70.1 48.1 137.7 57.9 87.1 40.1 78.1 100.8 94.2 13.7 80.1 64.0 35.1 55.9 59.8 60.9 33.8 41.8 35.0 39.1 66.3 17.8 36.0 53.0 45.2 36.2 77.0 89.4 31.0 52.8 49.7 47.6 41.7 54.9 43.1 17.1 14.3 43.6 57.1 38.4 35.8 112.4 50.0 63.8 66.3 68.2 26.2 26.2 44.8 40.4 45.0 25.4 40.7 41.4 37.3 102.3 78.5 56.4 51.6 63.6 33.0 33.7 35.9 40.6 33.4 38.0 37.5 37.7 38.7 35.5 36.1 38.3 17.6 6.4 18.4 0.0 26.4 32.5 24.1 33.0 11.4 24.2 37.7 24.9 48.1 30.0 21.6 27.6 8.4 84.9 87.3 38.6 56.7 49.7 23.6 15.0 23.9 27.1 41.8 102.5 0.0 79.4 282.2 24.9 15.8 13.8 21.5 13.1 22.1 41.7 152.7 26.9 0.0 58.1 32.6 72.2 105.7 61.3 25.7 67.6 35.6 0.0 215.5 28.3 193.6 0.0 0.0 71.8 31.9 30.9 25.7 46.0 49.7 62.2 23.4 21.7 39.5 14.8 31.4 123.5 79.4 19.0 40.3 65.7 36.2 16.0 35.5 34.6 UBE2L6 UBCH8 ENSG00000156587 "Ubiquitin conjugating enzyme E2 L6" O14933 11 57551656-57568284 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 165.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003328, CAB073407" Enhanced Approved Cytosol NA NA 15000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "CAB073407: , HPA003328: AB_1858539" "prognostic favorable (6.75e-4)" "unprognostic (2.10e-2)" "unprognostic (1.09e-2)" "unprognostic (2.93e-2)" "unprognostic (1.72e-1)" "unprognostic (1.18e-1)" "unprognostic (3.13e-2)" "unprognostic (4.74e-2)" "unprognostic (1.36e-2)" "unprognostic (1.37e-3)" "prognostic unfavorable (4.88e-4)" "unprognostic (3.07e-2)" "unprognostic (1.02e-2)" "unprognostic (1.28e-1)" "unprognostic (4.17e-2)" "unprognostic (1.88e-2)" "unprognostic (6.42e-2)" 70.7 60.4 84.4 92.3 84.8 85.5 51.1 80.0 95.2 54.2 70.7 46.3 47.6 44.1 68.5 42.7 66.1 66.6 35.2 80.2 88.0 51.5 121.1 91.1 119.9 93.6 88.1 61.5 24.3 39.9 36.8 53.1 86.2 47.0 43.6 23.6 103.3 49.2 14.3 36.1 57.6 67.3 96.2 126.4 55.6 17.1 94.6 113.4 37.4 29.3 86.7 76.0 44.4 86.1 55.6 26.2 85.8 29.0 179.2 222.3 9.7 30.2 178.8 261.3 337.0 9.8 140.9 169.3 110.3 92.5 223.3 43.7 38.0 99.4 55.4 163.9 1.5 169.2 0.0 38.0 330.7 38.8 54.3 238.9 22.9 122.8 33.6 96.2 83.9 173.2 7.9 118.5 47.8 67.6 280.1 92.2 23.3 0.5 33.3 243.1 52.9 118.4 71.0 58.5 2.1 45.2 60.3 5.4 139.9 15.3 68.3 20.3 30.9 56.3 19.6 43.6 10.2 162.1 176.6 3.4 161.0 98.8 12.3 508.1 534.8 487.8 359.2 638.4 394.1 379.2 368.2 377.9 401.3 310.9 315.1 331.1 838.8 486.9 556.7 256.3 513.7 1060.5 84.4 84.8 80.0 95.2 80.2 88.0 93.6 88.1 86.2 96.2 94.6 86.1 94.6 28.9 22.2 2.9 53.5 23.3 26.2 75.7 26.2 12.4 31.9 38.7 6.0 24.3 38.2 12.9 4.2 4.2 59.3 16.4 64.6 95.4 4.9 16.6 83.4 65.5 23.9 53.0 2.0 65.2 38.1 43.8 23.0 16.4 53.9 41.3 53.2 35.3 165.3 13.5 4.8 38.6 48.8 77.4 36.9 10.9 48.1 73.1 8.8 9.4 79.0 54.0 97.9 3.5 2.0 37.3 48.1 33.4 51.4 52.8 47.7 32.3 33.3 4.4 26.3 15.4 33.8 2.4 9.8 25.6 27.7 3.4 68.8 26.9 22.7 33.3 UGGT1 "HUGT1, UGCGL1" ENSG00000136731 "UDP-glucose glycoprotein glucosyltransferase 1" Q9NYU2 2 128091200-128195677 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012761, HPA015127" Enhanced Uncertain Cytosol NA NA 4000000 "Cluster 24: B-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 52: Non-specific - Transcription" Cytosol "HPA012761: AB_1858597, HPA015127: AB_1858596" "unprognostic (1.57e-1)" "unprognostic (1.80e-1)" "unprognostic (6.14e-2)" "unprognostic (1.87e-1)" "unprognostic (4.63e-2)" "unprognostic (6.45e-2)" "unprognostic (7.03e-3)" "unprognostic (3.13e-2)" "unprognostic (3.02e-2)" "unprognostic (1.05e-1)" "unprognostic (4.09e-3)" "unprognostic (7.05e-2)" "prognostic unfavorable (6.37e-4)" "unprognostic (3.86e-1)" "unprognostic (1.50e-1)" "unprognostic (2.23e-2)" "unprognostic (8.38e-3)" 8.1 8.5 4.2 13.7 4.6 21.8 7.6 4.8 6.5 9.1 5.0 12.4 9.0 7.3 19.9 8.0 6.5 6.5 8.0 4.3 4.6 8.2 14.9 8.4 12.3 4.7 4.4 5.1 14.8 8.7 6.5 8.7 5.0 8.7 10.0 9.7 8.6 6.2 13.2 8.8 10.2 6.2 4.0 9.4 10.7 6.4 4.8 11.7 10.4 13.0 12.6 7.5 6.6 5.6 34.8 11.8 22.0 47.6 28.0 22.3 34.3 39.4 16.7 12.7 11.3 26.0 24.9 49.4 15.4 28.3 11.3 25.3 16.8 16.8 25.5 31.5 8.2 43.4 14.9 82.3 28.0 58.6 25.9 16.3 13.0 25.4 23.0 25.0 29.8 19.8 28.4 25.6 26.9 24.4 23.5 33.5 39.5 24.0 12.4 19.2 21.3 20.9 23.8 25.2 11.7 17.4 27.3 36.0 24.4 22.5 14.4 40.2 43.1 34.6 24.4 20.1 28.4 27.3 40.4 22.3 29.3 31.4 32.6 3.8 2.5 2.5 2.3 2.5 2.3 1.6 1.9 2.1 1.9 3.3 1.6 2.3 3.7 1.9 2.5 3.1 1.6 1.4 4.2 4.6 4.8 6.5 4.3 4.6 4.7 4.4 5.0 4.0 4.8 5.6 14.6 35.3 24.7 24.8 14.3 8.2 6.4 11.1 5.7 19.8 11.2 7.1 16.7 12.8 20.7 3.7 22.9 10.5 22.1 21.5 1.9 14.0 9.2 18.4 27.7 16.5 22.8 31.5 40.6 19.5 20.1 16.6 21.9 22.2 11.4 20.8 17.9 39.7 16.6 20.2 37.6 21.9 8.2 25.4 16.4 2.3 14.9 20.0 14.2 32.8 26.0 7.5 15.5 31.2 46.5 19.4 10.4 13.5 31.5 13.3 25.3 8.4 12.7 20.2 6.6 18.5 13.3 10.0 8.5 9.4 10.7 10.8 18.9 16.0 22.8 10.1 ULK1 "ATG1, ATG1A" ENSG00000177169 "Unc-51 like autophagy activating kinase 1" O75385 12 131894622-131923150 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Autophagy "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 84.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.0;plasmacytoid DC: 3.8" "Group enriched" "Detected in many" 4 "dendritic cells: 3.8;granulocytes: 4.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063990 Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 24: NB-4 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol "HPA063990: AB_2685167" "unprognostic (1.53e-1)" "unprognostic (5.19e-2)" "unprognostic (2.52e-3)" "unprognostic (2.21e-3)" "unprognostic (8.01e-3)" "unprognostic (5.48e-2)" "unprognostic (2.74e-2)" "unprognostic (5.04e-3)" "unprognostic (3.94e-3)" "unprognostic (2.03e-2)" "unprognostic (9.09e-3)" "unprognostic (8.19e-2)" "unprognostic (6.25e-2)" "unprognostic (2.38e-1)" "unprognostic (2.75e-1)" "unprognostic (1.82e-2)" "unprognostic (3.16e-1)" 19.9 30.1 21.2 7.2 46.0 31.4 20.9 8.3 28.4 31.5 6.2 31.2 9.0 27.2 6.5 21.5 27.2 9.3 35.0 24.4 4.7 21.7 36.4 20.9 6.7 10.9 8.7 39.9 55.6 12.1 47.2 7.1 9.6 27.8 2.3 14.4 21.4 9.4 81.6 43.1 19.5 4.9 1.5 29.3 27.8 17.8 9.9 7.9 24.5 13.8 2.9 23.1 26.8 12.4 9.1 28.8 13.1 16.4 5.8 4.7 17.8 14.1 10.1 5.9 4.8 6.3 9.2 2.4 14.5 10.0 12.0 8.9 3.0 5.6 1.7 9.8 17.2 6.1 25.2 8.6 10.8 4.4 12.9 8.6 15.1 6.6 2.7 16.4 7.3 18.2 8.1 7.0 4.0 20.6 27.5 25.6 14.4 4.3 27.2 20.5 4.7 12.2 3.5 11.1 33.1 18.2 15.1 15.3 7.9 13.1 23.4 29.5 14.2 14.1 8.3 24.8 6.6 30.9 12.0 3.3 23.8 7.6 16.6 0.2 0.9 1.4 0.4 0.4 0.1 0.1 0.3 0.4 0.2 0.3 0.2 0.3 4.0 0.1 0.4 3.8 0.3 0.4 21.2 46.0 8.3 28.4 24.4 4.7 10.9 8.7 9.6 1.5 9.9 12.4 15.6 16.0 17.4 17.9 7.8 14.4 6.1 11.6 9.6 25.0 19.6 14.4 22.0 15.7 15.6 7.3 39.6 5.7 23.7 10.5 1.9 8.5 0.8 19.1 35.7 14.9 19.2 12.0 27.0 12.7 4.2 13.1 13.3 28.0 3.8 24.4 8.6 33.8 5.4 53.8 21.9 14.6 18.3 12.0 6.7 3.0 12.5 13.1 5.4 11.2 12.3 14.7 5.2 20.1 13.9 24.5 7.7 15.8 11.9 15.0 9.9 3.2 13.9 84.3 13.1 19.5 16.9 6.8 7.5 9.7 19.5 17.2 9.1 8.8 7.7 9.5 UMPS ENSG00000114491 "Uridine monophosphate synthetase" P11172 3 124730433-124749273 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Decarboxylase, Glycosyltransferase, Lyase, Multifunctional enzyme, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 109.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036178, HPA036179" Uncertain Approved Cytosol NA NA 9200 "Cluster 26: Non-specific - Mitochondria" "Cluster 45: Intestine - Brush border" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA036178: AB_10673002, HPA036179: AB_10673615" "unprognostic (6.41e-2)" "unprognostic (6.70e-2)" "unprognostic (1.79e-2)" "unprognostic (1.13e-3)" "unprognostic (2.70e-1)" "unprognostic (1.72e-1)" "unprognostic (1.15e-3)" "unprognostic (5.51e-2)" "unprognostic (4.85e-3)" "unprognostic (1.43e-1)" "unprognostic (5.36e-2)" "prognostic unfavorable (9.20e-4)" "unprognostic (2.18e-2)" "unprognostic (1.58e-2)" "unprognostic (1.91e-1)" "unprognostic (4.61e-2)" "unprognostic (1.31e-1)" 1.3 1.4 2.5 1.2 2.5 1.3 1.8 2.8 2.9 1.0 1.1 2.3 2.0 1.3 1.0 2.0 1.8 0.7 0.8 2.6 1.8 1.8 2.6 0.9 1.4 2.8 2.1 1.9 2.1 1.5 0.8 0.7 2.3 1.4 1.6 1.8 1.3 0.7 3.1 2.3 2.1 1.1 2.0 2.6 1.8 0.9 2.3 1.8 1.1 0.7 1.7 0.8 1.0 3.5 1.4 4.4 5.1 2.1 2.9 3.4 5.4 7.9 2.4 3.1 2.6 3.8 2.1 4.0 8.2 3.0 7.9 9.0 7.1 2.4 5.0 4.4 4.2 8.2 3.0 2.7 2.6 8.7 6.0 3.8 2.3 1.8 3.9 1.9 1.2 8.2 3.7 1.9 2.3 3.5 10.8 1.7 12.1 3.9 2.7 7.4 6.0 3.3 2.4 2.5 4.0 2.6 11.3 4.2 4.3 3.7 4.1 3.1 15.4 2.5 5.2 7.4 3.2 8.0 12.5 12.1 2.8 3.4 2.6 5.9 10.3 5.5 14.0 11.3 12.4 17.0 9.2 12.1 14.6 24.3 13.9 10.8 0.7 12.8 9.3 11.0 12.4 11.9 2.5 2.5 2.8 2.9 2.6 1.8 2.8 2.1 2.3 2.0 2.3 3.5 9.6 6.4 11.5 6.5 11.2 15.8 24.5 41.3 18.8 8.3 8.9 12.3 6.2 20.0 22.8 9.2 4.2 66.8 13.2 9.0 29.4 29.8 3.2 10.9 18.2 15.2 9.6 16.2 11.0 30.5 35.0 12.7 14.3 12.1 12.0 22.8 7.9 31.4 22.0 5.0 12.0 10.3 20.3 7.0 5.9 4.4 13.7 8.3 3.6 10.3 18.0 11.0 13.4 15.6 12.2 23.4 8.6 13.9 10.4 14.6 14.0 25.9 22.1 9.1 13.1 13.3 17.1 23.2 32.1 20.6 19.0 109.2 11.0 29.5 17.8 21.1 UNC45B "CMYA4, UNC45" ENSG00000141161 "Unc-45 myosin chaperone B" Q8IWX7 17 35147817-35189345 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Myogenesis" "Chaperone, Developmental protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 59 "heart muscle: 100.3;skeletal muscle: 196.6;tongue: 151.9" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 201.8;Late spermatids: 59.4" "Group enriched" "Detected in some" 5 "head and neck cancer: 0.9;testis cancer: 1.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.1" "Lineage enriched" "Detected in single" 9 "T-cells: 1.1" "Group enriched" "Detected in some" 11 "BEWO: 1.7;HSkMC: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA017861 Approved Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "HPA017861: AB_1847012" "unprognostic (7.17e-2)" "unprognostic (6.47e-3)" "unprognostic (9.36e-3)" "unprognostic (2.93e-1)" "unprognostic (1.49e-3)" "unprognostic (5.30e-2)" "unprognostic (3.07e-1)" "unprognostic (1.09e-2)" "unprognostic (5.46e-2)" "unprognostic (2.40e-2)" "unprognostic (8.46e-2)" "unprognostic (6.73e-2)" "unprognostic (1.13e-6)" "unprognostic (6.77e-2)" "unprognostic (5.05e-3)" "unprognostic (2.20e-1)" "unprognostic (2.21e-1)" 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.1 100.3 0.2 0.1 0.1 0.0 0.7 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 2.1 0.0 0.0 2.5 0.0 196.6 0.1 0.0 0.1 0.1 1.4 0.4 1.3 0.1 0.4 0.0 151.9 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.9 0.0 0.2 0.5 0.0 0.0 0.1 0.6 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.3 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 201.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.9 0.0 24.6 0.0 0.0 2.3 0.0 2.7 0.4 0.0 0.5 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.4 59.4 0.6 0.1 0.0 1.9 0.0 0.0 1.0 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.3 4.5 0.2 0.7 0.0 0.1 0.0 1.1 0.5 0.0 0.1 UNG "DGU, HIGM4, UDG, UNG1, UNG2" ENSG00000076248 "Uracil DNA glycosylase" P13051 12 109097597-109110992 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 64.9;Spermatogonia: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB011605 Uncertain Approved Cytosol NA Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "CAB011605: AB_778737" "unprognostic (4.38e-2)" "unprognostic (3.82e-3)" "unprognostic (1.03e-2)" "unprognostic (1.33e-2)" "unprognostic (4.64e-1)" "unprognostic (4.10e-2)" "prognostic unfavorable (6.40e-4)" "unprognostic (5.68e-3)" "prognostic unfavorable (3.06e-4)" "unprognostic (4.66e-2)" "unprognostic (8.78e-3)" "unprognostic (1.91e-1)" "unprognostic (1.35e-3)" "unprognostic (2.57e-2)" "unprognostic (4.50e-1)" "unprognostic (1.40e-2)" "unprognostic (6.89e-2)" 19.8 56.7 32.4 14.7 32.4 16.0 23.1 30.1 34.8 16.6 27.7 28.0 17.1 14.5 12.7 29.7 15.6 10.4 21.1 29.2 34.9 27.5 32.2 9.6 18.0 32.2 31.4 15.7 12.4 33.2 10.9 17.8 34.1 13.6 29.3 6.8 17.7 17.6 43.0 32.7 18.8 14.5 31.6 16.1 17.7 24.3 33.5 22.8 22.2 33.5 27.0 13.5 20.1 30.8 77.1 77.5 72.8 66.6 118.6 33.8 69.5 44.4 30.1 68.6 52.3 61.7 51.6 100.3 65.1 40.2 35.9 47.6 81.4 46.0 66.4 85.6 150.9 98.1 41.1 105.5 17.7 147.6 58.2 30.7 41.6 33.0 18.3 54.6 50.4 117.8 80.9 32.5 47.0 96.2 136.8 173.6 130.0 124.2 117.7 123.9 109.8 85.9 43.4 95.6 103.3 57.4 79.6 67.8 39.5 94.2 126.2 68.2 26.0 59.1 52.7 39.3 62.5 62.6 145.0 190.5 44.8 97.7 73.8 12.9 2.7 5.0 22.4 5.3 31.6 16.0 25.5 25.6 6.8 17.2 16.4 18.4 0.0 16.5 5.5 4.9 25.5 14.4 32.4 32.4 30.1 34.8 29.2 34.9 32.2 31.4 34.1 31.6 33.5 30.8 26.6 0.0 4.8 16.0 9.2 18.0 11.0 13.2 25.0 2.6 21.7 14.1 12.4 7.2 5.0 42.3 4.2 64.9 12.5 14.7 19.6 14.4 3.4 7.6 15.0 17.7 8.4 32.4 7.0 6.2 38.1 12.6 14.3 9.9 7.6 24.8 20.3 20.8 18.3 5.0 6.2 21.4 10.2 3.8 5.4 4.2 14.0 5.5 14.2 6.5 3.8 15.8 7.2 6.6 4.0 5.0 10.3 14.7 16.7 6.8 9.3 20.2 3.2 3.5 6.6 10.2 11.5 21.9 74.6 37.8 20.9 20.4 15.3 25.7 40.4 9.7 UNKL "C16orf28, FLJ23360, ZC3H5L, ZC3HDC5L" ENSG00000059145 "Unk like zinc finger" Q9H9P5 16 1363205-1414751 "Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055801, HPA073949" Uncertain Supported Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 9: U-2 OS - Unknown function" "Cluster 52: Non-specific - Transcription" Cytosol "HPA055801: AB_2682926, HPA073949: AB_2686647" "unprognostic (5.32e-3)" "unprognostic (1.24e-1)" "unprognostic (1.36e-1)" "unprognostic (8.88e-2)" "unprognostic (4.08e-2)" "unprognostic (1.82e-2)" "unprognostic (3.90e-3)" "unprognostic (8.07e-2)" "unprognostic (5.18e-2)" "unprognostic (8.56e-2)" "unprognostic (4.85e-3)" "unprognostic (1.13e-1)" "unprognostic (3.86e-3)" "unprognostic (1.89e-1)" "unprognostic (6.27e-2)" "unprognostic (2.85e-1)" "unprognostic (1.55e-1)" 6.9 7.5 4.5 4.0 3.1 5.6 7.3 9.0 8.3 7.5 0.5 6.5 4.1 8.9 0.7 4.4 8.4 1.8 4.4 4.6 3.5 3.9 4.3 5.3 4.3 8.8 5.4 10.7 4.2 2.0 5.1 3.0 8.9 7.0 1.4 2.6 6.9 3.0 11.5 7.6 7.4 1.7 2.2 8.2 5.6 6.6 6.3 5.4 7.9 2.3 2.8 7.3 6.2 5.2 4.7 12.3 2.8 7.2 2.1 2.6 21.5 12.0 3.6 3.2 2.8 10.1 10.7 1.8 24.4 4.1 5.5 8.6 3.6 1.3 2.2 22.0 10.4 3.7 14.8 8.3 1.6 2.1 7.5 3.4 1.6 5.1 2.1 3.8 5.7 5.4 10.6 6.5 1.5 7.4 5.5 6.0 7.8 2.0 13.4 14.7 3.2 13.7 2.0 1.3 9.4 5.6 7.1 4.4 1.3 2.0 7.1 3.4 6.9 7.1 10.9 6.1 5.1 14.2 8.0 8.4 5.7 4.2 8.3 3.5 1.1 2.7 2.1 0.4 1.0 0.7 0.7 0.5 0.4 0.9 1.5 0.7 4.1 1.4 0.4 1.8 0.9 0.7 4.5 3.1 9.0 8.3 4.6 3.5 8.8 5.4 8.9 2.2 6.3 5.2 7.6 6.4 7.5 18.3 16.0 5.5 6.2 5.0 3.4 30.0 8.1 9.5 2.7 7.2 8.3 5.5 14.6 12.8 16.2 5.3 1.9 5.4 5.7 4.9 6.4 8.9 3.6 6.1 13.3 3.0 6.6 8.7 6.6 7.0 5.1 20.6 12.5 6.8 4.1 6.7 15.7 6.5 6.1 7.3 3.8 20.8 16.4 6.2 7.2 9.4 13.9 16.6 23.7 13.0 17.2 7.3 11.3 15.4 17.1 22.7 11.5 2.0 8.0 37.3 6.6 12.5 8.3 14.2 20.0 4.5 8.2 20.5 11.8 9.4 4.9 11.7 URGCP "DKFZp666G166, DKFZp686O0457, FLJ20654, KIAA1507, URG4" ENSG00000106608 "Upregulator of cell proliferation" Q8TCY9 7 43875894-43926411 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019879, HPA020134, HPA029468" Approved Supported Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA019879: AB_1858651, HPA020134: AB_1858652, HPA029468: AB_10601831" "unprognostic (5.66e-2)" "unprognostic (1.10e-3)" "unprognostic (1.18e-1)" "unprognostic (2.75e-1)" "unprognostic (2.21e-3)" "unprognostic (2.42e-2)" "unprognostic (3.74e-2)" "unprognostic (1.26e-1)" "unprognostic (3.79e-1)" "unprognostic (2.21e-1)" "unprognostic (3.23e-3)" "unprognostic (3.71e-1)" "prognostic favorable (1.90e-4)" "unprognostic (1.56e-2)" "unprognostic (8.69e-2)" "unprognostic (4.51e-2)" "unprognostic (1.69e-3)" 15.9 35.6 25.1 9.9 24.6 10.3 15.0 24.5 25.9 19.7 24.1 22.6 24.3 17.7 14.7 17.8 19.5 11.1 25.2 24.5 22.5 24.3 29.6 14.2 10.8 20.7 20.0 20.7 19.1 22.1 27.4 11.9 21.3 21.6 19.0 20.1 15.6 16.1 34.9 18.6 22.8 18.7 19.2 18.5 17.4 9.7 23.4 10.4 18.7 31.6 10.6 20.4 16.6 23.8 28.2 25.1 10.1 32.1 26.3 24.0 9.6 33.2 58.4 35.2 35.6 21.1 21.8 16.5 16.9 31.7 53.5 44.3 28.0 23.8 34.3 31.6 17.3 11.5 25.2 19.0 28.0 17.7 20.3 18.5 28.5 27.8 27.0 23.1 17.7 18.9 28.6 13.1 23.7 21.0 18.6 14.6 19.1 33.1 25.8 24.9 14.6 22.2 33.7 27.7 25.8 44.4 34.4 49.6 15.4 16.5 25.0 21.0 19.5 20.3 9.4 22.8 26.1 34.1 53.6 20.7 23.2 26.7 38.6 4.5 4.7 6.2 8.8 7.4 9.4 5.8 9.2 11.7 10.2 4.9 9.9 8.8 0.5 2.8 8.3 1.6 10.6 6.6 25.1 24.6 24.5 25.9 24.5 22.5 20.7 20.0 21.3 19.2 23.4 23.8 10.1 3.2 9.2 14.7 12.2 11.1 13.4 7.9 9.1 25.9 17.7 17.8 23.8 12.8 7.3 12.9 8.4 6.3 8.9 41.0 17.6 13.0 1.2 16.3 14.3 10.2 8.4 6.3 28.6 13.2 11.8 13.5 23.9 23.2 7.0 21.1 12.5 27.3 6.5 16.8 25.1 12.5 10.2 5.0 10.2 3.4 18.3 7.5 12.4 6.5 4.8 12.2 7.2 7.5 17.6 15.7 23.4 18.8 4.2 14.1 37.9 26.4 8.7 20.4 6.6 13.8 12.6 8.8 8.3 9.1 14.8 3.4 10.8 15.2 16.2 15.0 USH1C "AIE-75, DFNB18, harmonin, NY-CO-37, NY-CO-38, PDZ-73, PDZ73, PDZD7C" ENSG00000006611 "USH1 protein network component harmonin" Q9Y6N9 11 17493895-17544416 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Hearing" "Cancer-related genes, Deafness, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 97.8;kidney: 54.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 190.0;Muller glia cells: 163.6;Paneth cells: 203.0;Proximal enterocytes: 430.7;Proximal tubular cells: 190.3;Undifferentiated cells: 115.7" "Group enriched" "Detected in many" 7 "colorectal cancer: 34.5;pancreatic cancer: 18.8;renal cancer: 29.4;stomach cancer: 15.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CACO-2: 60.6;HeLa: 21.8;OE19: 57.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB013690, HPA027398, HPA027492, HPA028033" Enhanced Enhanced Cytosol No NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Cytosol "CAB013690: , HPA027398: AB_10601775, HPA027492: AB_10601898, HPA028033: AB_10601782" "unprognostic (3.60e-2)" "unprognostic (6.19e-2)" "unprognostic (2.36e-1)" "unprognostic (3.83e-2)" "unprognostic (1.98e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (2.22e-1)" "unprognostic (2.78e-1)" "unprognostic (1.51e-2)" "unprognostic (9.65e-2)" "prognostic favorable (9.41e-4)" "unprognostic (1.29e-2)" "unprognostic (1.88e-1)" "unprognostic (1.62e-1)" "unprognostic (2.61e-1)" 0.4 0.3 2.8 5.9 6.8 0.0 0.2 2.8 3.9 0.1 1.5 51.5 97.8 0.1 0.3 0.0 2.9 25.9 0.1 9.0 4.7 54.0 0.6 0.1 0.1 6.1 5.7 0.0 3.9 0.0 6.7 0.0 7.0 0.0 48.3 19.0 0.0 0.3 0.0 0.0 96.5 2.1 4.1 0.0 26.7 0.2 5.9 0.1 1.1 0.0 0.0 0.6 0.1 8.3 0.0 1.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 60.6 8.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 21.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 57.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 6.8 2.8 3.9 9.0 4.7 6.1 5.7 7.0 4.1 5.9 8.3 0.0 0.0 0.0 18.3 1.6 0.0 0.1 0.0 0.0 0.7 0.0 1.3 0.6 52.9 0.7 5.5 2.1 0.0 0.0 190.0 21.5 20.5 1.0 1.7 0.0 0.4 64.0 0.0 0.6 27.5 0.0 0.3 53.5 0.0 4.5 0.0 0.0 0.0 0.0 1.7 0.2 92.9 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 163.6 0.0 0.5 36.4 56.0 203.0 0.0 0.2 0.0 430.7 190.3 1.0 4.9 0.0 0.0 0.1 0.1 1.3 0.0 0.0 0.0 0.8 0.1 115.7 0.1 USP25 USP21 ENSG00000155313 "Ubiquitin specific peptidase 25" Q9UHP3 21 15730025-15880069 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 120.9" "Cell type enhanced" "Detected in all" "Early spermatids: 166.7;Excitatory neurons: 148.0;Late spermatids: 192.8;Oligodendrocyte precursor cells: 150.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018297, HPA024142" Approved Supported Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA018297: AB_1858672, HPA024142: AB_1858673" "unprognostic (6.35e-2)" "unprognostic (1.50e-1)" "unprognostic (6.90e-2)" "unprognostic (6.29e-2)" "unprognostic (1.39e-1)" "unprognostic (2.88e-2)" "unprognostic (3.91e-2)" "unprognostic (1.65e-1)" "unprognostic (1.44e-2)" "unprognostic (1.38e-1)" "unprognostic (2.33e-2)" "unprognostic (1.40e-1)" "unprognostic (8.24e-3)" "unprognostic (2.34e-3)" "unprognostic (4.50e-2)" "unprognostic (1.61e-1)" "unprognostic (2.32e-2)" 25.8 12.9 13.4 16.8 20.1 26.9 17.6 12.6 17.2 18.1 12.3 15.3 12.6 26.8 18.7 21.4 16.8 12.4 28.1 16.2 4.2 21.4 20.2 24.0 20.1 4.7 4.3 14.1 15.9 14.3 7.6 29.4 4.8 17.9 16.1 9.5 17.5 24.6 120.9 13.1 13.3 36.4 4.4 19.5 13.1 54.5 4.9 25.6 15.5 75.1 19.3 15.5 17.3 11.9 31.2 23.1 21.5 3.2 38.7 57.5 25.3 22.0 21.8 16.0 20.1 20.5 17.4 33.6 31.5 34.9 24.3 16.4 16.7 29.1 22.0 33.5 19.1 27.5 23.5 15.8 64.3 36.6 12.1 37.6 34.7 25.8 74.0 41.7 57.0 30.0 35.9 61.4 29.1 13.0 42.1 7.1 26.6 12.5 20.3 31.8 20.0 25.8 43.5 8.3 4.7 12.8 31.4 26.2 20.9 25.9 14.0 21.3 54.6 24.8 16.0 26.2 12.5 17.7 11.9 26.8 16.0 16.1 18.6 0.0 1.4 1.9 1.8 1.4 2.0 1.6 1.5 3.2 1.2 1.1 1.4 2.1 2.9 1.1 1.3 1.3 2.2 0.8 13.4 20.1 12.6 17.2 16.2 4.2 4.7 4.3 4.8 4.4 4.9 11.9 30.4 57.7 29.5 47.3 21.7 17.1 18.8 9.7 15.9 6.2 17.4 11.8 55.7 15.7 24.2 22.0 4.2 39.0 21.4 20.3 5.9 9.4 166.7 24.0 19.0 19.7 9.6 21.5 148.0 13.4 8.4 19.4 17.9 34.6 6.3 14.4 17.9 18.0 13.3 5.0 98.4 12.8 8.2 24.2 16.0 192.8 19.0 24.2 16.0 86.2 23.7 4.0 23.7 150.3 72.4 13.4 8.4 12.8 15.9 22.0 11.9 15.1 23.4 6.7 19.7 26.1 17.2 11.2 5.8 22.7 19.2 33.1 26.9 18.5 11.6 20.4 USP31 KIAA1203 ENSG00000103404 "Ubiquitin specific peptidase 31" Q70CQ4 16 23061406-23149270 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.2" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 198.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006937 Uncertain Approved Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA006937: AB_1080523" "unprognostic (6.45e-2)" "unprognostic (2.42e-1)" "unprognostic (1.08e-1)" "unprognostic (4.43e-3)" "unprognostic (1.24e-1)" "unprognostic (1.28e-1)" "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.03e-1)" "unprognostic (2.52e-1)" "unprognostic (6.15e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (4.41e-5)" "unprognostic (5.59e-2)" "unprognostic (3.75e-1)" "unprognostic (3.07e-1)" "unprognostic (1.98e-3)" 5.5 2.9 7.5 2.0 23.4 4.3 6.7 18.9 13.0 12.9 0.7 4.2 1.7 11.0 3.8 6.0 5.3 1.9 9.2 10.0 10.5 3.6 5.6 6.1 1.8 22.3 20.3 2.2 4.3 5.5 5.7 3.9 21.3 7.5 2.3 3.2 4.6 4.1 8.9 11.2 2.6 7.5 11.3 1.6 2.6 11.8 20.6 2.6 3.0 8.4 2.5 7.5 7.9 31.2 12.0 12.4 3.5 4.9 6.2 4.8 3.3 4.1 3.7 5.1 6.1 7.9 7.1 4.0 4.2 5.1 8.3 15.2 8.7 15.9 8.4 2.9 3.5 1.6 7.4 16.7 7.8 4.2 4.3 4.1 13.5 9.5 21.8 1.9 9.3 3.9 4.9 12.0 7.1 8.0 2.0 3.5 6.9 3.9 3.8 9.9 9.8 7.9 7.7 17.5 9.3 6.0 6.3 12.4 3.6 3.9 5.0 9.2 5.5 10.3 7.6 5.3 11.2 3.9 7.0 4.2 7.4 5.5 4.2 0.0 0.1 0.1 0.1 0.0 0.3 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.2 0.0 7.5 23.4 18.9 13.0 10.0 10.5 22.3 20.3 21.3 11.3 20.6 31.2 25.9 6.4 3.7 11.1 2.2 66.8 62.7 35.5 44.9 13.7 7.6 19.8 13.6 7.2 10.9 5.5 2.1 13.8 3.6 2.7 0.0 7.0 4.8 20.6 12.8 17.6 4.8 8.2 59.2 8.6 7.5 6.9 2.0 13.2 1.3 23.7 7.5 27.7 4.7 0.0 49.6 3.5 12.2 3.5 10.8 10.4 7.8 5.0 7.2 32.8 3.1 4.0 3.1 31.7 198.7 7.9 2.0 4.5 2.8 32.0 1.5 11.6 17.6 8.1 19.7 8.8 11.2 24.2 57.1 17.4 26.6 7.5 2.9 4.4 6.4 23.9 VARS1 "VARS, VARS2" ENSG00000204394 "Valyl-tRNA synthetase 1" P26640 6 31777518-31795752 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 10.1;Cytotrophoblasts: 23.2;Extravillous trophoblasts: 48.3;Hofbauer cells: 30.7;Syncytiotrophoblasts: 16.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "U-266/84: 140.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046710 Approved Enhanced Cytosol NA NA 110000 "Cluster 39: Non-specific - mRNA processing" "Cluster 71: Testis - DNA repair" "Cluster 16: U-266 - Nucleosome" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA046710: AB_2679765" "unprognostic (1.86e-2)" "prognostic unfavorable (7.25e-4)" "unprognostic (2.19e-1)" "unprognostic (2.07e-1)" "unprognostic (2.49e-2)" "unprognostic (3.43e-2)" "prognostic unfavorable (1.86e-4)" "prognostic unfavorable (6.90e-4)" "unprognostic (3.20e-1)" "unprognostic (2.76e-1)" "unprognostic (4.72e-1)" "unprognostic (1.28e-1)" "unprognostic (1.09e-2)" "unprognostic (1.98e-1)" "unprognostic (1.69e-1)" "unprognostic (3.85e-2)" "unprognostic (2.59e-1)" 22.2 24.6 2.0 6.6 1.6 3.2 21.9 0.4 2.4 20.1 0.0 21.0 5.6 29.4 0.9 32.5 22.1 1.1 20.0 0.7 2.3 19.2 29.3 19.8 3.0 2.4 1.9 19.7 37.3 2.5 33.6 2.2 2.2 17.6 1.7 1.3 20.6 1.2 58.2 34.3 21.9 3.5 0.8 30.0 23.3 63.6 2.6 3.0 18.5 3.1 2.8 23.5 20.7 1.5 36.2 11.6 12.4 36.9 9.1 8.5 84.0 52.2 10.8 25.2 13.3 11.5 9.9 58.3 60.2 18.4 18.9 22.0 33.5 32.4 8.8 46.0 74.0 31.7 18.4 21.3 18.3 75.7 60.6 12.5 8.2 14.8 16.5 6.2 13.5 22.9 92.2 48.8 12.7 13.2 51.0 16.2 35.0 11.9 32.5 55.5 20.5 132.7 13.0 12.4 42.1 26.2 12.0 31.0 19.5 5.8 23.2 34.0 31.2 24.2 37.8 28.2 72.5 87.9 140.4 44.1 14.6 31.1 29.0 0.0 0.3 0.1 0.2 0.3 0.3 0.5 0.3 0.3 0.5 0.3 0.3 0.1 0.1 0.5 0.3 0.6 0.1 0.5 2.0 1.6 0.4 2.4 0.7 2.3 2.4 1.9 2.2 0.8 2.6 1.5 4.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 23.2 1.9 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 48.3 3.6 0.0 0.0 0.0 0.0 0.0 0.0 30.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 16.6 0.4 0.0 0.0 0.0 VASH2 FLJ12505 ENSG00000143494 "Vasohibin 2" Q86V25 1 212950520-212992037 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 7.9" "Group enriched" "Detected in many" 6 "Early spermatids: 92.8;Late spermatids: 80.8" "Cancer enhanced" "Detected in many" "testis cancer: 3.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 24.2;AN3-CA: 29.6;NTERA-2: 46.2;RH-30: 135.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045820 Approved Cytosol "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "HPA045820: " "unprognostic (2.22e-1)" "unprognostic (1.15e-1)" "unprognostic (2.87e-1)" "unprognostic (1.29e-2)" "unprognostic (1.28e-1)" "unprognostic (1.57e-2)" "unprognostic (1.25e-2)" "unprognostic (4.04e-2)" "unprognostic (2.59e-3)" "unprognostic (3.50e-2)" "unprognostic (2.45e-1)" "unprognostic (6.58e-2)" "unprognostic (1.84e-5)" "unprognostic (1.95e-3)" "unprognostic (2.74e-1)" "unprognostic (6.85e-2)" "unprognostic (6.81e-4)" 1.7 0.1 0.9 3.3 0.8 0.9 2.0 0.2 1.1 1.7 0.0 0.5 0.7 1.9 0.4 4.0 0.7 2.6 1.1 0.6 0.4 0.4 0.2 1.1 2.3 1.6 0.9 0.6 0.2 0.8 2.6 0.8 1.6 2.7 0.6 0.5 0.9 0.8 0.5 0.5 0.9 1.8 0.2 1.2 0.8 7.9 2.1 4.3 0.3 0.8 2.1 1.4 0.5 0.7 0.3 1.7 24.2 29.6 0.2 0.1 4.0 0.1 0.0 1.0 1.3 0.1 0.6 0.1 0.4 0.1 0.6 0.1 9.9 0.0 1.2 20.3 3.7 2.0 1.4 1.5 0.1 0.2 0.4 3.8 0.0 1.3 0.0 0.6 0.3 11.4 0.1 5.9 2.0 0.5 13.1 1.5 46.2 0.0 3.6 7.6 135.5 1.3 0.2 1.9 5.6 8.6 3.1 0.2 0.3 12.4 4.5 0.9 0.0 1.0 2.7 0.6 1.3 3.4 6.2 0.9 0.1 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.9 0.8 0.2 1.1 0.6 0.4 1.6 0.9 1.6 0.2 2.1 0.7 0.9 0.0 1.1 0.0 0.6 1.5 0.8 0.2 5.7 3.0 4.1 6.0 1.2 0.0 0.0 0.0 2.1 0.1 12.6 0.2 0.0 0.7 92.8 0.9 1.4 1.1 1.2 0.8 5.4 0.2 0.3 10.9 2.0 1.0 0.0 11.2 0.0 0.1 0.2 1.7 4.3 0.2 2.0 0.3 3.2 80.8 0.3 1.5 0.0 0.0 0.7 0.4 0.0 0.5 0.6 0.1 0.0 0.7 1.0 1.5 0.0 0.4 0.9 2.0 0.0 8.4 4.0 3.2 1.1 0.4 1.6 0.0 0.5 0.1 0.3 0.4 VAT1L KIAA1576 ENSG00000171724 "Vesicle amine transport 1 like" Q9HCJ6 16 77788564-77980107 "Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "adrenal gland: 70.1;brain: 186.9;choroid plexus: 232.4;retina: 188.7" "Group enriched" "Detected in some" 4 "Horizontal cells: 297.8;Muller glia cells: 106.9" "Cancer enhanced" "Detected in many" "glioma: 7.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 23.1;BJ hTERT+: 68.7;fHDF/TERT166: 38.1;NTERA-2: 79.9;U-87 MG: 82.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044061, CAB046032, HPA061138" Enhanced Approved Cytosol NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 62: Horizontal cells - Visual perception" Cytosol "CAB046032: AB_11126308, HPA044061: AB_10959610, HPA061138: " "unprognostic (1.49e-2)" "unprognostic (8.74e-3)" "unprognostic (8.80e-3)" "unprognostic (3.39e-2)" "unprognostic (3.62e-2)" "unprognostic (1.70e-2)" "unprognostic (2.39e-3)" "unprognostic (1.37e-1)" "unprognostic (1.86e-1)" "unprognostic (7.65e-2)" "unprognostic (8.57e-3)" "unprognostic (2.46e-1)" "prognostic unfavorable (3.01e-6)" "unprognostic (2.50e-2)" "unprognostic (6.53e-2)" "unprognostic (1.19e-1)" "unprognostic (5.96e-2)" 1.8 70.1 30.0 3.3 38.1 0.8 0.5 45.7 24.1 0.7 232.4 3.6 2.3 5.4 6.8 1.7 0.9 4.0 15.2 19.6 186.9 5.3 1.0 0.3 0.4 60.2 53.2 0.3 1.8 0.7 4.5 1.9 84.0 0.3 5.6 188.7 1.4 0.4 0.2 0.1 3.2 2.5 49.9 0.0 1.9 1.9 67.4 0.1 2.4 0.3 2.3 1.4 1.2 37.4 0.0 0.0 23.1 0.0 7.8 0.0 0.0 2.8 68.7 0.9 0.7 0.0 0.0 0.0 0.0 38.1 0.7 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.8 0.0 0.5 0.1 1.7 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.4 79.9 0.0 0.0 1.9 0.0 0.0 0.0 0.0 3.0 3.7 0.0 1.1 0.0 14.1 0.1 18.6 0.1 0.0 8.6 0.0 0.0 0.0 0.0 0.0 82.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.0 38.1 45.7 24.1 19.6 186.9 60.2 53.2 84.0 49.9 67.4 37.4 0.1 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 7.0 0.1 0.5 9.2 4.3 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.2 4.4 0.0 0.2 0.9 3.0 0.0 20.7 0.0 0.0 1.5 0.0 0.1 0.0 0.1 0.4 0.0 0.2 297.8 31.3 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 1.0 0.6 106.9 0.0 44.7 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.5 0.0 1.8 0.0 0.0 0.3 0.1 0.1 0.0 0.0 VAV1 VAV ENSG00000141968 "Vav guanine nucleotide exchange factor 1" P15498 19 6772708-6857366 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 54.1;lymphoid tissue: 46.4" "Cell type enhanced" "Detected in many" "B-cells: 30.7;dendritic cells: 31.3;granulocytes: 34.9;Hofbauer cells: 50.6;Kupffer cells: 29.4;Macrophages: 33.9;Microglial cells: 30.9;T-cells: 26.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 100.7;Karpas-707: 114.7;MOLT-4: 115.8;REH: 76.1;THP-1: 88.9;U-266/84: 89.5;U-937: 95.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001864, HPA005925" Enhanced Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" Cytosol "HPA001864: AB_1858722, HPA005925: " "unprognostic (2.93e-1)" "unprognostic (1.96e-1)" "unprognostic (1.80e-1)" "unprognostic (1.01e-1)" "unprognostic (6.82e-2)" "unprognostic (1.13e-2)" "unprognostic (5.62e-1)" "unprognostic (1.97e-1)" "unprognostic (1.30e-2)" "unprognostic (1.90e-2)" "unprognostic (3.56e-2)" "unprognostic (8.58e-2)" "prognostic unfavorable (1.48e-4)" "unprognostic (9.55e-2)" "unprognostic (1.78e-1)" "unprognostic (6.57e-2)" "unprognostic (3.28e-1)" 6.6 3.8 3.3 36.3 3.3 54.1 2.7 3.6 4.6 2.6 4.5 6.5 5.8 1.8 1.4 3.7 2.4 6.3 1.9 3.3 4.4 2.1 5.0 11.5 46.4 6.2 4.9 1.1 1.3 4.2 1.6 8.7 5.6 2.8 7.1 0.2 6.1 2.3 1.0 1.7 14.1 5.3 5.0 44.9 5.5 1.8 5.7 45.7 2.0 2.1 39.1 13.0 1.7 7.6 1.6 2.2 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 12.7 51.0 16.5 0.0 0.0 0.2 0.0 0.0 0.0 22.0 1.8 61.8 0.0 0.0 0.0 60.7 100.7 0.0 0.0 0.0 0.0 0.0 0.0 63.9 2.3 114.7 0.0 9.6 115.8 36.6 0.0 0.0 0.0 76.1 0.0 41.0 2.2 0.0 0.0 0.0 0.0 18.3 0.1 0.0 8.0 88.9 0.2 0.0 1.6 0.1 0.1 69.9 89.5 57.9 0.1 95.3 0.0 1.6 18.3 20.0 22.0 30.3 15.7 14.3 16.1 19.3 16.6 13.6 17.2 15.6 40.6 19.2 39.8 14.4 14.5 18.2 3.3 3.3 3.6 4.6 3.3 4.4 6.2 4.9 5.6 5.0 5.7 7.6 0.5 3.2 3.0 0.0 30.7 1.3 0.8 3.7 0.0 0.5 0.4 0.4 1.1 0.0 6.9 0.0 0.0 0.8 31.3 1.5 0.0 4.2 5.4 5.3 0.3 1.5 1.2 9.9 1.9 0.4 0.7 1.2 1.1 1.1 34.9 0.0 1.8 0.3 50.6 0.0 1.5 1.0 8.2 29.4 19.6 2.2 0.0 33.9 1.8 30.9 18.8 0.0 22.6 0.5 1.2 9.9 6.1 0.0 21.6 0.3 0.0 0.2 11.9 0.0 0.0 0.3 1.2 1.7 1.4 0.3 0.9 1.4 26.5 0.3 2.4 0.6 VCPKMT "C14orf138, METTL21D, VCP-KMT" ENSG00000100483 "Valosin containing protein lysine methyltransferase" Q9H867 14 50108632-50116600 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001146, HPA076561" Uncertain Supported Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "HPA001146: AB_1845558, HPA076561: AB_2732312" "unprognostic (1.58e-1)" "unprognostic (2.87e-2)" "unprognostic (5.05e-2)" "unprognostic (3.86e-1)" "unprognostic (3.54e-1)" "unprognostic (4.74e-2)" "unprognostic (9.97e-2)" "prognostic favorable (2.40e-4)" "unprognostic (8.20e-2)" "unprognostic (1.74e-1)" "unprognostic (4.90e-2)" "prognostic unfavorable (4.75e-4)" "prognostic unfavorable (6.79e-4)" "unprognostic (1.15e-1)" "unprognostic (1.48e-1)" "unprognostic (1.66e-1)" "unprognostic (6.27e-2)" 2.9 4.1 1.7 3.4 2.1 5.1 2.3 2.4 5.3 3.7 3.0 3.3 1.7 3.0 2.6 4.9 2.9 2.3 2.7 2.5 2.0 2.7 3.9 3.1 4.3 2.0 1.9 2.6 2.9 1.9 3.3 1.6 2.0 2.7 1.6 1.5 2.2 1.6 2.3 3.9 3.2 1.5 1.5 4.8 3.6 2.1 2.2 4.7 2.6 1.8 4.4 3.0 3.2 2.5 4.2 4.4 4.0 4.9 2.6 3.1 4.4 4.0 4.4 4.4 3.3 2.8 4.8 12.8 2.7 2.8 1.1 7.9 4.9 7.0 4.4 6.4 3.2 2.5 1.7 2.8 3.6 6.4 3.3 2.0 3.9 4.8 4.9 3.0 5.5 4.6 3.0 5.3 3.3 5.5 13.4 6.7 3.9 6.1 7.2 9.0 7.4 3.4 5.6 6.3 6.7 7.9 5.9 1.6 7.1 3.6 4.0 5.7 1.4 7.2 5.6 2.6 4.5 5.1 11.4 5.0 2.5 5.2 3.5 12.1 2.8 0.0 9.3 4.7 10.9 27.1 9.1 11.5 3.8 21.4 11.2 12.4 0.8 11.8 2.2 5.4 7.8 4.8 1.7 2.1 2.4 5.3 2.5 2.0 2.0 1.9 2.0 1.5 2.2 2.5 11.5 12.8 9.8 7.8 38.0 30.3 17.3 7.7 30.1 6.5 12.8 10.8 3.6 8.6 9.7 7.3 10.4 10.2 25.7 5.6 9.8 5.8 39.4 14.1 9.8 8.3 5.4 9.5 12.6 5.7 8.4 9.3 7.7 17.1 17.7 7.2 6.8 7.7 5.1 1.7 11.0 8.5 12.2 7.5 16.4 10.2 7.5 8.7 10.6 3.7 9.5 3.5 15.5 10.6 17.5 5.3 8.0 4.9 48.2 15.5 7.8 6.7 8.6 8.1 0.0 9.1 9.1 14.4 16.6 24.9 37.4 11.5 22.4 10.2 7.1 17.1 VPS11 "PEP5, RNF108" ENSG00000160695 "VPS11 core subunit of CORVET and HOPS complexes" Q9H270 11 119067818-119081972 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039020 Approved Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 89: Fibroblasts - ECM organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 4: Macrophages - Innate immune response" Cytosol "HPA039020: AB_10674847" "unprognostic (6.97e-2)" "unprognostic (3.76e-1)" "unprognostic (1.77e-1)" "unprognostic (1.15e-2)" "unprognostic (1.43e-2)" "unprognostic (1.28e-1)" "unprognostic (2.59e-3)" "unprognostic (1.11e-1)" "unprognostic (3.21e-1)" "unprognostic (9.17e-2)" "unprognostic (6.01e-2)" "unprognostic (1.56e-1)" "prognostic favorable (1.44e-4)" "unprognostic (4.07e-2)" "unprognostic (4.05e-2)" "unprognostic (2.71e-2)" "unprognostic (2.25e-1)" 21.6 25.1 16.7 14.7 16.8 17.6 19.4 16.7 18.6 20.8 15.3 19.6 13.4 23.5 19.0 14.6 20.1 12.8 16.6 17.6 17.8 16.9 11.5 16.8 18.1 17.0 17.6 22.5 18.0 22.4 22.8 17.3 17.3 18.4 13.4 17.6 18.2 16.5 21.7 21.4 17.9 19.5 16.0 21.7 18.5 13.3 17.5 20.1 21.1 21.1 17.2 21.0 17.4 18.4 11.6 11.8 12.8 9.8 27.5 24.2 14.0 15.4 18.4 15.3 16.5 19.9 24.2 16.6 21.5 30.2 27.1 21.0 16.1 20.7 15.1 17.1 8.0 36.6 12.0 19.5 30.8 22.9 21.5 29.6 21.3 23.2 15.9 27.2 24.4 13.9 29.5 28.8 20.2 30.5 19.3 21.6 6.4 21.2 22.5 21.7 21.1 12.6 18.2 24.1 10.2 17.5 19.2 25.3 16.8 13.7 38.3 20.1 24.5 19.1 7.1 6.9 11.5 11.3 11.0 15.6 14.0 27.2 17.0 24.8 16.8 12.8 16.4 13.9 16.8 11.3 13.7 15.2 20.7 11.9 12.9 16.6 3.8 16.5 19.0 8.7 16.5 13.9 16.7 16.8 16.7 18.6 17.6 17.8 17.0 17.6 17.3 16.0 17.5 18.4 9.9 6.4 10.5 8.1 10.2 2.9 4.4 7.0 8.6 10.2 8.1 9.8 7.6 8.6 12.1 9.2 12.5 11.2 16.2 9.7 9.8 8.2 7.8 9.9 10.0 10.7 9.6 6.3 9.6 10.1 7.0 9.7 11.2 9.9 15.2 10.2 13.2 6.0 17.0 5.0 9.9 10.1 6.1 14.8 8.9 3.0 17.1 12.6 7.2 7.5 11.6 9.2 5.2 6.6 14.4 7.2 6.8 15.4 11.5 3.6 9.2 11.0 10.5 15.5 13.1 6.2 10.2 11.3 7.3 6.5 4.8 14.1 12.2 9.4 9.5 3.8 VSNL1 "HLP3, HPCAL3, HUVISL1, VILIP, VILIP-1" ENSG00000163032 "Visinin like 1" P62760 2 17539126-17657018 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "brain: 663.3" "Group enriched" "Detected in many" 4 "Excitatory neurons: 442.7;Inhibitory neurons: 243.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 663.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HaCaT: 125.9;Hep G2: 124.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053808 Approved Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA053808: AB_2682270" "unprognostic (1.04e-1)" "unprognostic (7.90e-2)" "unprognostic (3.44e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (6.90e-4)" "unprognostic (4.90e-2)" "unprognostic (5.48e-2)" "unprognostic (2.81e-2)" "unprognostic (4.66e-2)" "unprognostic (2.99e-1)" "unprognostic (1.65e-1)" "unprognostic (2.18e-1)" "unprognostic (5.14e-4)" "unprognostic (3.26e-2)" "unprognostic (1.23e-1)" "unprognostic (6.19e-3)" "unprognostic (1.51e-2)" 0.8 27.5 100.4 1.4 143.0 0.1 6.2 12.9 663.3 13.5 0.0 4.6 0.2 1.1 0.0 47.9 2.0 0.2 39.7 105.8 12.3 1.9 20.8 2.9 0.1 21.6 0.0 3.6 1.2 0.2 2.7 5.4 19.7 3.9 5.4 18.6 9.7 0.8 1.3 13.8 0.3 1.1 0.0 0.3 1.4 0.8 4.3 1.1 0.8 2.9 7.3 1.5 26.3 188.8 0.7 0.1 1.4 21.2 2.4 3.0 0.1 0.0 0.0 0.0 0.6 0.3 13.6 0.0 0.0 0.0 0.0 125.9 0.8 4.0 0.0 0.0 0.5 0.0 0.1 124.4 0.0 0.0 0.3 0.9 6.0 0.0 2.9 0.1 0.0 0.0 0.1 0.6 1.6 0.0 0.0 0.1 21.0 6.7 0.0 0.1 0.1 0.0 0.0 0.4 9.3 8.5 0.0 0.0 0.0 4.9 0.0 0.1 0.0 4.2 0.0 0.0 2.4 0.1 0.0 0.0 3.4 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 100.4 143.0 12.9 663.3 105.8 12.3 21.6 0.0 19.7 0.0 4.3 188.8 0.1 0.0 0.5 41.1 0.0 18.2 29.8 54.3 59.2 8.8 4.9 19.7 30.8 4.3 18.0 0.0 0.0 0.3 0.1 2.2 1.9 0.1 5.1 0.0 0.1 1.1 1.2 0.0 442.7 0.2 0.2 5.9 0.0 0.1 0.0 0.1 0.0 17.8 0.6 3.3 243.2 7.1 18.3 0.3 0.8 6.5 0.6 0.5 3.6 54.4 0.6 3.7 0.0 36.7 42.9 0.2 1.0 0.0 0.0 15.0 0.0 4.0 0.8 14.7 0.0 0.2 1.3 1.7 0.9 85.5 20.2 0.4 0.8 1.8 5.6 14.2 VWDE FLJ14712 ENSG00000146530 "Von Willebrand factor D and EGF domains" Q8N2E2 7 12330885-12403941 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 4.3;salivary gland: 3.3;thyroid gland: 3.1" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 8.8;Excitatory neurons: 11.8;Granulosa cells: 5.4;Inhibitory neurons: 11.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 5.0;K-562: 13.0;NTERA-2: 4.8;SCLC-21H: 7.0" "Low region specificity" "Detected in many" "HPA026619, HPA036044, HPA036045" Uncertain Approved Cytosol "Secreted - unknown location" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA026619: AB_2671920, HPA036044: AB_2674916, HPA036045: " "unprognostic (6.39e-2)" "unprognostic (1.65e-3)" "unprognostic (5.36e-3)" "unprognostic (1.78e-4)" "unprognostic (1.39e-2)" "unprognostic (4.19e-3)" "unprognostic (2.38e-1)" "unprognostic (1.85e-1)" "unprognostic (1.78e-1)" "unprognostic (6.25e-2)" "unprognostic (1.68e-1)" "unprognostic (6.72e-2)" "unprognostic (1.84e-1)" "unprognostic (2.11e-3)" "unprognostic (1.58e-1)" "unprognostic (1.10e-1)" "unprognostic (2.73e-1)" 0.0 0.3 0.5 0.1 0.8 2.3 1.6 0.0 0.5 0.1 0.0 0.3 0.1 0.4 4.3 0.1 1.1 0.4 2.0 0.4 0.3 0.2 0.1 0.2 0.1 0.4 0.4 0.0 0.0 0.3 0.4 0.1 0.3 1.1 0.1 0.0 3.3 1.6 0.0 0.4 0.1 0.1 0.5 0.1 0.7 0.2 0.3 0.1 3.1 0.0 0.0 0.4 0.0 0.1 0.0 0.8 0.0 1.2 0.0 0.2 2.4 0.0 1.5 0.5 0.7 0.3 2.4 0.1 0.0 0.0 0.9 0.7 1.7 1.6 1.1 2.7 2.4 3.4 5.0 0.0 0.0 1.9 1.5 0.1 0.2 0.0 1.1 2.4 1.0 1.3 13.0 0.0 0.0 1.6 0.0 0.0 4.8 0.0 0.8 0.0 0.0 1.1 0.4 1.2 7.0 1.5 0.0 1.4 0.0 1.7 0.0 0.8 0.1 0.0 0.9 0.0 1.5 2.2 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.8 0.0 0.5 0.4 0.3 0.4 0.4 0.3 0.5 0.3 0.1 0.1 0.0 1.5 0.3 0.0 0.3 2.1 0.9 2.8 0.0 1.6 1.0 8.8 0.0 1.2 0.0 0.0 0.3 0.0 0.2 0.0 0.1 1.2 0.7 0.2 0.2 0.0 3.0 11.8 0.0 0.5 1.1 0.0 1.8 0.0 5.4 0.0 0.0 0.1 0.0 11.6 0.1 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.4 1.2 0.0 0.0 2.9 0.0 0.0 1.5 0.0 0.0 0.0 0.2 0.4 0.4 0.7 0.1 0.1 0.7 0.4 0.5 1.8 WARS1 "IFI53, IFP53, WARS" ENSG00000140105 "Tryptophanyl-tRNA synthetase 1" P23381 14 100333790-100376805 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 324.4" "Cell type enhanced" "Detected in some" "Adipocytes: 66.4;Cytotrophoblasts: 16.5;Endothelial cells: 38.5;Hofbauer cells: 43.1;Syncytiotrophoblasts: 16.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 1345.3;non-classical monocyte: 1608.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 908.5;SK-MEL-30: 1012.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005573, HPA018944" Enhanced Enhanced Cytosol No No 49000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" Cytosol "HPA005573: AB_2667366, HPA018944: AB_2669986" "unprognostic (5.36e-2)" "unprognostic (5.98e-2)" "unprognostic (3.99e-2)" "unprognostic (1.54e-1)" "unprognostic (2.30e-1)" "unprognostic (9.25e-2)" "prognostic unfavorable (7.88e-4)" "unprognostic (5.14e-2)" "unprognostic (4.26e-2)" "prognostic favorable (1.94e-4)" "unprognostic (4.84e-2)" "unprognostic (3.21e-1)" "unprognostic (3.53e-3)" "unprognostic (1.37e-1)" "unprognostic (9.45e-2)" "unprognostic (1.62e-1)" "unprognostic (5.92e-3)" 100.7 67.9 40.3 185.6 44.4 70.5 65.4 40.1 45.5 35.9 45.2 67.8 44.8 39.6 70.3 54.4 50.8 48.7 157.6 44.2 56.0 83.6 47.9 207.5 139.0 72.0 52.6 21.2 47.5 39.2 63.4 324.4 65.3 49.1 72.0 37.8 49.5 38.3 74.7 28.4 67.7 76.2 47.6 110.6 70.1 67.7 55.0 61.7 159.9 67.0 86.2 107.7 30.7 44.9 91.2 85.7 54.6 319.1 78.7 110.7 87.3 117.4 220.7 232.1 301.4 57.4 80.2 101.7 105.5 277.4 59.7 151.1 158.8 130.3 153.1 154.4 48.3 64.1 60.9 72.3 908.5 184.9 101.6 126.9 186.9 141.3 290.1 74.5 225.0 66.1 202.8 255.0 107.5 178.0 64.3 87.1 55.4 94.1 152.2 51.4 86.5 64.9 119.3 80.8 145.7 84.9 69.4 58.7 1012.4 70.5 153.6 234.7 153.1 25.7 58.9 269.2 61.3 446.4 277.1 191.9 295.0 144.2 205.5 96.5 471.7 610.4 41.5 1345.3 38.4 71.4 34.5 38.4 337.9 68.0 24.8 28.6 170.9 44.5 1608.2 54.7 44.8 672.7 40.3 44.4 40.1 45.5 44.2 56.0 72.0 52.6 65.3 47.6 55.0 44.9 66.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 16.5 3.7 0.0 0.0 0.0 0.0 0.0 0.0 38.5 0.0 0.0 0.0 0.0 11.5 5.5 0.0 0.0 0.0 0.0 0.0 0.0 43.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 16.6 0.5 0.0 0.0 0.0 WBP1 WBP-1 ENSG00000239779 "WW domain binding protein 1" Q96G27 2 74458400-74460891 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 29.0;Gastric mucus-secreting cells: 33.1;Plasma cells: 57.2;Squamous epithelial cells: 28.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057067 Approved Approved Cytosol No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Transcription" Cytosol "HPA057067: AB_2683326" "unprognostic (5.94e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (1.04e-4)" "unprognostic (6.05e-2)" "unprognostic (2.98e-1)" "unprognostic (1.11e-1)" "unprognostic (5.80e-2)" "unprognostic (1.32e-2)" "unprognostic (1.03e-1)" "unprognostic (1.91e-1)" "prognostic favorable (6.83e-4)" "unprognostic (1.17e-2)" "unprognostic (1.87e-2)" "unprognostic (1.78e-1)" "unprognostic (1.57e-1)" "unprognostic (5.09e-2)" "prognostic favorable (6.36e-4)" 36.9 70.7 141.7 19.6 145.8 31.9 37.7 139.4 171.9 48.2 133.1 46.6 29.1 39.1 44.8 35.7 56.1 36.5 49.9 137.7 136.6 71.2 80.3 33.7 32.2 144.2 141.3 55.6 62.3 73.7 60.8 24.9 138.2 69.9 17.7 24.4 56.4 37.3 31.4 34.9 33.2 19.8 138.1 42.5 58.0 31.8 145.0 44.7 66.9 53.9 20.6 45.7 37.5 139.0 20.6 91.3 56.2 66.7 69.9 54.0 45.7 20.6 40.3 22.4 17.5 47.3 41.9 19.4 39.3 48.9 33.2 28.3 24.8 55.8 19.0 74.3 49.1 27.4 41.4 68.9 47.6 10.3 27.4 76.2 58.9 30.4 42.2 93.8 44.7 51.6 11.5 72.0 54.8 133.8 40.1 25.5 43.3 53.6 46.3 36.4 63.5 33.6 55.9 83.1 35.0 81.3 28.2 49.9 62.5 49.4 65.5 26.9 26.5 53.0 41.9 20.0 23.5 106.7 38.8 22.2 56.2 27.0 48.5 24.1 28.5 19.2 26.5 23.5 22.5 28.4 23.0 25.5 30.2 27.8 31.3 28.0 18.6 34.6 20.1 47.0 39.2 27.1 141.7 145.8 139.4 171.9 137.7 136.6 144.2 141.3 138.2 138.1 145.0 139.0 1.5 3.2 4.2 0.0 14.3 0.9 0.6 2.0 29.0 1.6 3.2 2.2 0.5 0.0 4.2 1.8 2.1 1.4 1.7 3.3 1.9 5.5 2.4 3.1 2.4 3.6 1.8 9.7 0.0 3.9 1.4 7.2 33.1 1.8 1.3 1.1 0.4 0.8 1.7 0.0 0.0 4.7 2.0 2.4 1.0 1.8 2.1 7.1 0.0 0.0 6.0 1.7 2.1 0.0 0.0 5.2 3.1 1.2 57.2 1.2 5.6 3.3 13.1 1.7 0.0 0.5 5.8 0.6 0.2 28.1 1.3 1.8 10.4 0.9 3.7 0.3 WBP2NL "FLJ26145, GRAMD7, MGC26816, PAWP" ENSG00000183066 "WBP2 N-terminal like" Q6ICG8 22 41998725-42058456 "Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 17.8" "Group enriched" "Detected in many" 10 "Early spermatids: 254.5;Late spermatids: 807.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA048557 Enhanced Approved Cytosol NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA048557: AB_2680440" "unprognostic (1.90e-2)" "unprognostic (2.25e-4)" "unprognostic (2.77e-3)" "unprognostic (6.12e-2)" "unprognostic (6.48e-2)" "unprognostic (1.43e-1)" "unprognostic (1.41e-2)" "unprognostic (1.04e-2)" "unprognostic (1.38e-1)" "unprognostic (2.96e-1)" "unprognostic (9.84e-4)" "unprognostic (3.31e-2)" "unprognostic (4.19e-2)" "unprognostic (1.79e-1)" "unprognostic (2.06e-1)" "unprognostic (2.85e-3)" "unprognostic (9.36e-5)" 0.2 0.1 0.6 0.0 0.6 0.0 0.7 0.6 0.9 0.2 0.0 0.2 0.1 0.2 1.2 0.1 0.5 0.2 0.0 0.6 0.6 0.3 0.1 0.3 0.2 1.0 0.7 0.6 0.7 0.4 0.3 0.1 1.0 0.3 0.1 0.7 0.5 0.3 0.1 0.4 0.2 0.1 0.8 0.2 0.3 17.8 0.5 0.1 0.6 0.1 0.1 0.1 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.6 0.6 0.9 0.6 0.6 1.0 0.7 1.0 0.8 0.5 1.4 0.3 0.0 2.8 50.6 4.3 0.4 2.1 1.0 2.8 16.4 1.8 2.4 0.7 2.8 3.7 0.0 20.9 2.2 0.6 1.7 3.9 0.9 254.5 0.9 1.5 1.3 4.8 0.4 16.0 1.3 1.0 0.9 1.5 1.3 0.0 4.7 2.2 1.5 1.4 10.1 18.6 2.2 4.1 2.8 1.9 807.7 6.5 2.3 1.8 9.4 1.8 2.9 3.1 9.5 16.6 0.9 3.9 5.7 1.5 1.2 3.4 2.0 0.8 23.0 0.0 0.6 0.7 30.6 20.2 1.2 0.9 1.9 1.9 1.6 2.7 1.4 WDR59 FLJ12270 ENSG00000103091 "WD repeat domain 59" Q6PJI9 16 74871362-75000173 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041084, HPA048218" Approved Approved Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "HPA041084: AB_10793867, HPA048218: AB_2680318" "unprognostic (3.68e-1)" "unprognostic (1.10e-1)" "unprognostic (1.65e-2)" "unprognostic (4.16e-2)" "unprognostic (6.14e-2)" "unprognostic (3.99e-1)" "unprognostic (2.28e-2)" "unprognostic (8.83e-2)" "unprognostic (3.43e-1)" "unprognostic (2.37e-2)" "unprognostic (4.21e-3)" "unprognostic (3.25e-3)" "unprognostic (2.05e-2)" "unprognostic (9.08e-2)" "unprognostic (3.88e-2)" "unprognostic (1.78e-1)" "unprognostic (5.61e-2)" 11.6 19.0 18.2 13.8 22.1 16.1 14.2 18.2 21.3 19.2 15.5 15.3 13.1 16.1 21.1 17.3 14.9 9.7 17.0 17.9 20.0 17.3 35.7 11.1 12.7 19.0 19.3 22.4 16.9 22.6 22.9 14.1 19.8 15.8 14.0 37.9 14.1 11.6 24.8 21.1 16.4 13.2 17.2 15.3 14.2 13.9 20.6 22.3 22.9 17.4 16.0 14.5 17.3 28.5 15.6 23.8 27.1 25.8 20.8 18.7 22.9 9.8 17.0 20.7 23.5 32.3 27.1 21.8 10.6 18.3 19.3 24.6 21.7 23.4 29.3 13.2 23.1 27.9 16.3 52.5 12.6 20.4 32.7 21.8 18.7 25.1 23.7 26.7 21.7 52.5 42.0 10.6 9.9 46.1 31.4 36.4 21.6 34.0 9.7 31.3 11.9 18.3 22.2 13.9 16.5 18.2 28.0 16.2 12.6 28.5 24.5 17.8 19.0 12.9 19.6 14.8 8.5 20.1 29.3 47.2 22.8 14.1 14.3 0.7 0.7 0.7 1.0 0.4 3.4 1.9 1.9 1.5 0.4 1.1 1.2 1.4 0.7 1.0 0.8 0.7 1.0 0.4 18.2 22.1 18.2 21.3 17.9 20.0 19.0 19.3 19.8 17.2 20.6 28.5 9.8 16.0 16.5 77.1 15.0 22.4 20.0 12.7 21.6 38.8 15.0 16.3 17.6 21.5 15.0 22.0 62.6 34.4 9.6 13.1 9.8 13.0 37.4 13.1 14.6 11.8 22.1 21.0 41.5 9.6 16.5 13.6 17.3 20.1 13.3 22.4 17.9 24.6 10.8 20.2 53.8 11.9 12.2 13.2 17.1 79.2 13.4 12.7 8.8 29.0 15.3 11.9 14.4 65.9 88.8 11.9 14.0 11.7 5.9 24.1 17.0 19.6 16.7 55.5 19.7 17.1 9.7 17.7 19.1 16.5 24.2 47.3 15.3 13.8 16.8 23.4 WHAMM "KIAA1971, WHAMM1, WHDC1" ENSG00000156232 "WASP homolog associated with actin, golgi membranes and microtubules" Q8TF30 15 82809628-82836108 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 29.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039690, HPA040231" Approved Supported Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "HPA039690: AB_10795405, HPA040231: AB_10795361" "unprognostic (7.98e-2)" "prognostic favorable (7.09e-4)" "unprognostic (1.21e-1)" "unprognostic (8.56e-2)" "unprognostic (6.68e-2)" "unprognostic (8.21e-3)" "unprognostic (1.82e-1)" "unprognostic (1.37e-2)" "unprognostic (1.32e-1)" "unprognostic (2.09e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (2.31e-4)" "unprognostic (1.31e-1)" "unprognostic (1.65e-2)" "unprognostic (1.04e-1)" "unprognostic (1.14e-1)" "unprognostic (2.20e-2)" 7.7 4.8 4.3 3.9 4.4 29.7 7.2 6.1 4.7 6.6 8.8 6.8 4.6 5.5 2.8 7.2 6.1 2.9 5.8 4.3 3.9 7.0 8.8 7.8 5.5 4.5 4.3 7.2 7.5 6.1 5.4 4.6 4.3 7.7 4.0 4.0 6.6 3.5 17.7 9.0 7.3 3.3 3.8 8.5 6.2 3.7 4.3 5.1 6.6 7.8 4.7 7.5 6.4 5.8 4.0 4.1 2.5 3.6 7.9 5.5 4.2 5.5 5.5 6.0 5.9 2.6 7.2 8.7 6.7 5.2 5.6 8.8 7.7 4.5 3.9 2.9 4.4 5.0 4.5 3.9 8.0 3.6 5.7 5.4 6.0 2.8 5.9 6.0 4.3 4.1 4.6 11.3 6.0 3.1 3.0 5.2 1.0 5.0 2.4 4.4 5.3 2.5 10.4 16.1 2.3 1.9 8.5 5.5 5.8 5.1 3.7 7.7 6.8 7.9 2.7 5.3 6.3 12.0 7.3 4.2 5.6 4.9 5.0 2.6 0.5 0.5 1.2 0.4 1.0 1.0 1.1 0.8 0.3 1.1 1.0 1.0 1.3 2.3 0.4 0.9 1.0 0.4 4.3 4.4 6.1 4.7 4.3 3.9 4.5 4.3 4.3 3.8 4.3 5.8 36.6 16.0 17.3 18.9 37.1 26.5 42.8 6.6 34.1 16.2 16.7 17.7 15.6 17.2 7.6 20.2 14.6 14.5 47.3 18.1 5.9 8.9 6.9 19.6 13.9 23.2 6.7 31.5 10.1 10.3 16.6 18.7 23.9 29.4 10.8 12.6 19.2 13.8 19.9 23.5 15.9 19.4 6.1 15.8 41.4 5.5 17.4 25.4 19.6 15.0 19.3 17.9 61.8 14.1 23.4 13.0 15.5 23.7 24.1 49.0 16.8 11.2 7.1 18.0 32.9 24.5 19.5 29.8 31.1 29.2 25.1 25.4 36.1 15.5 13.8 75.1 WNK1 "HSAN2, HSN2, PPP1R167, PRKWNK1" ENSG00000060237 "WNK lysine deficient protein kinase 1" Q9H4A3 12 752579-911452 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Protein kinase inhibitor, Serine/threonine-protein kinase, Transferase" "Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 293.0" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 336.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046541, HPA059157" Enhanced Supported Cytosol NA NA 92000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA046541: AB_2679690, HPA059157: AB_2683935" "unprognostic (1.40e-1)" "unprognostic (1.54e-2)" "unprognostic (4.82e-2)" "unprognostic (1.75e-1)" "unprognostic (1.27e-1)" "unprognostic (7.68e-2)" "unprognostic (1.05e-3)" "unprognostic (1.57e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.67e-4)" "unprognostic (1.84e-1)" "unprognostic (2.49e-1)" "unprognostic (4.38e-1)" "unprognostic (1.40e-1)" "unprognostic (1.32e-1)" "unprognostic (5.17e-2)" "unprognostic (1.30e-2)" 56.7 20.6 190.8 36.4 236.8 54.2 33.5 179.4 166.1 32.8 110.8 22.8 14.4 26.7 30.4 72.1 29.4 27.1 63.8 132.3 161.1 84.0 31.6 44.6 39.2 232.3 238.4 30.1 22.5 51.1 17.0 36.0 217.0 29.7 24.2 87.4 24.0 33.4 79.7 52.0 17.4 36.1 225.4 30.2 27.6 48.3 238.0 61.3 27.7 79.8 46.9 35.8 43.8 293.0 53.9 97.5 131.8 11.3 88.1 80.0 52.2 48.3 61.6 58.2 51.3 59.4 55.7 71.0 16.8 107.8 73.5 39.8 93.8 56.7 84.3 124.7 51.4 169.4 122.2 46.1 66.7 86.9 68.2 64.0 82.1 97.6 164.4 61.6 73.4 68.0 76.4 158.2 77.8 54.1 154.6 15.6 105.8 47.8 24.3 78.0 138.8 20.8 80.6 96.8 35.1 40.7 121.8 82.9 33.6 183.3 86.8 97.2 78.3 67.1 77.3 86.2 70.8 23.8 43.1 103.8 59.4 44.6 53.2 0.7 1.8 1.6 1.9 2.1 1.9 1.7 1.9 2.1 1.4 1.2 1.2 1.9 5.6 1.4 4.7 1.2 3.4 1.6 190.8 236.8 179.4 166.1 132.3 161.1 232.3 238.4 217.0 225.4 238.0 293.0 261.1 102.5 141.6 77.1 65.3 112.8 42.3 38.3 85.4 87.9 50.6 39.5 241.6 50.1 47.1 90.1 150.1 32.5 83.0 27.8 86.1 28.0 29.7 63.0 68.6 106.7 58.7 304.2 182.3 24.4 32.9 58.3 37.2 70.2 52.6 46.2 52.5 71.7 57.3 84.1 165.0 26.3 16.2 121.4 80.8 21.2 61.8 96.7 37.4 114.3 95.7 64.0 61.8 126.7 336.4 41.7 34.8 55.7 76.5 59.0 24.2 21.8 64.6 96.1 13.1 69.6 63.8 186.5 74.6 147.2 136.0 28.5 112.9 33.2 25.8 55.2 WNK2 "KIAA1760, NY-CO-43, PRKWNK2, SDCCAG43" ENSG00000165238 "WNK lysine deficient protein kinase 2" Q9Y3S1 9 93184916-93320572 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 83.1;skeletal muscle: 62.3" "Cell type enhanced" "Detected in many" "Astrocytes: 76.4;Cone photoreceptor cells: 160.6;Excitatory neurons: 128.5;Inhibitory neurons: 98.8;Intestinal goblet cells: 77.3;Rod photoreceptor cells: 106.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 18.8;Hep G2: 31.0;SCLC-21H: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015555, HPA016519, CAB017813" Enhanced Approved Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB017813: , HPA015555: AB_2669218, HPA016519: AB_2669380" "unprognostic (5.02e-2)" "unprognostic (1.32e-2)" "unprognostic (2.61e-1)" "unprognostic (1.95e-1)" "unprognostic (2.28e-1)" "unprognostic (1.01e-1)" "unprognostic (2.04e-1)" "unprognostic (1.79e-3)" "unprognostic (1.94e-1)" "unprognostic (2.81e-2)" "unprognostic (1.31e-3)" "unprognostic (2.23e-1)" "unprognostic (4.48e-3)" "unprognostic (6.51e-2)" "unprognostic (1.44e-1)" "unprognostic (4.38e-4)" "unprognostic (1.62e-1)" 2.0 3.0 14.9 3.3 14.8 0.0 4.9 4.6 39.1 4.7 0.3 36.0 17.9 5.8 4.2 5.7 15.4 1.3 83.1 18.3 7.7 0.8 1.3 0.9 0.5 13.8 6.0 1.1 42.8 2.3 29.6 3.0 8.8 16.7 11.9 28.8 47.3 12.3 62.3 15.8 21.5 4.5 1.9 2.7 14.7 6.6 14.2 7.1 1.8 31.0 1.0 5.5 3.4 10.5 7.4 6.6 4.6 13.2 0.0 0.0 8.8 0.0 0.0 0.1 0.0 2.7 0.2 18.8 2.4 0.0 1.3 0.3 10.4 0.0 0.0 0.0 12.1 0.0 5.8 31.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 2.3 12.2 0.0 0.0 9.8 0.2 0.2 11.5 7.2 0.4 0.0 0.0 15.3 0.0 1.1 37.6 14.8 2.4 10.2 0.9 1.3 1.3 2.2 0.1 0.0 4.8 0.2 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 14.9 14.8 4.6 39.1 18.3 7.7 13.8 6.0 8.8 1.9 14.2 10.5 0.3 0.0 0.0 76.4 0.3 1.3 8.5 3.1 0.0 62.0 19.4 18.7 58.1 31.5 14.1 0.0 160.6 15.5 0.2 34.3 0.0 17.1 1.2 7.7 9.2 1.3 32.4 0.0 128.5 9.1 6.7 2.7 3.6 15.8 0.0 8.6 0.4 0.2 3.4 1.7 98.8 77.3 6.1 1.3 2.2 2.6 0.9 0.1 1.8 29.0 0.6 60.3 0.0 9.0 3.2 3.2 57.0 6.0 0.2 11.1 47.7 1.1 6.6 106.8 13.1 3.5 5.0 0.7 7.7 1.1 5.5 15.6 0.4 0.1 59.0 8.9 XPNPEP1 "XPNPEP, XPNPEPL, XPNPEPL1" ENSG00000108039 "X-prolyl aminopeptidase 1" Q9NQW7 10 109864766-109923553 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025196, HPA030419, HPA030420, HPA030422" Supported Enhanced Cytosol NA NA 810000 "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "CAB025196: , HPA030419: AB_10598917, HPA030420: AB_10611523, HPA030422: AB_10601783" "unprognostic (3.17e-2)" "unprognostic (2.36e-2)" "unprognostic (1.11e-1)" "unprognostic (2.31e-2)" "unprognostic (2.46e-1)" "unprognostic (2.01e-3)" "prognostic unfavorable (2.12e-5)" "unprognostic (8.03e-2)" "unprognostic (2.10e-2)" "unprognostic (1.88e-1)" "unprognostic (4.89e-2)" "unprognostic (7.61e-2)" "unprognostic (2.43e-2)" "unprognostic (1.34e-2)" "unprognostic (1.74e-1)" "unprognostic (2.40e-1)" "unprognostic (5.18e-2)" 19.7 19.4 13.2 22.9 13.6 23.3 20.1 13.1 14.8 19.7 17.2 32.2 51.7 19.4 22.7 25.1 22.3 27.5 27.9 15.3 13.4 21.4 18.9 19.2 25.4 13.2 12.7 19.8 62.0 24.5 19.2 26.6 13.1 21.7 40.4 18.7 30.4 15.7 28.4 29.5 61.8 28.2 13.2 19.3 24.4 18.1 13.3 19.5 23.6 22.1 28.4 24.6 19.3 13.7 78.1 33.6 52.3 72.1 83.6 77.4 40.2 42.4 85.5 61.8 66.5 65.4 65.2 110.3 35.9 65.0 31.3 40.5 41.7 52.2 60.4 33.0 40.3 74.0 20.5 27.6 58.2 58.3 59.0 76.9 31.8 67.8 60.1 94.6 103.1 70.0 24.3 34.3 80.1 26.3 41.7 36.0 20.6 58.7 35.7 46.1 105.3 19.8 78.5 24.3 15.9 60.5 36.9 23.1 70.6 56.9 28.3 53.6 53.9 25.3 32.9 40.4 38.1 58.4 30.4 92.8 59.4 80.0 20.3 25.7 26.8 11.3 19.5 42.2 13.4 10.6 12.6 17.5 46.4 8.9 8.7 11.7 2.2 30.5 36.8 36.4 15.5 29.6 13.2 13.6 13.1 14.8 15.3 13.4 13.2 12.7 13.1 13.2 13.3 13.7 13.4 6.4 14.4 24.5 14.6 8.9 13.2 32.9 11.4 20.5 12.1 9.7 17.0 18.6 26.3 3.7 6.2 38.2 33.1 34.5 17.6 37.4 6.4 12.3 16.5 18.2 16.8 14.7 18.9 72.9 29.6 22.7 24.5 13.6 11.4 17.0 15.7 12.1 30.9 26.9 25.3 37.1 18.3 20.5 9.6 5.1 18.3 37.5 8.8 15.9 33.5 27.1 24.7 21.6 27.0 54.4 35.1 29.7 18.1 22.5 63.5 31.1 22.8 19.5 13.1 9.8 14.2 17.5 35.9 18.6 8.7 25.2 19.4 30.0 36.5 27.1 YAE1 "C7orf36, CIAB2, GK003, YAE1D1" ENSG00000241127 "YAE1 maturation factor of ABCE1" Q9NRH1 7 39566385-39610320 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 17.2;Cytotrophoblasts: 15.1;Extravillous trophoblasts: 12.0;Fibroblasts: 6.2;Hofbauer cells: 10.0;Syncytiotrophoblasts: 5.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019226, HPA031249" Uncertain Approved Cytosol NA NA "Cluster 30: Non-specific - Translation" "Cluster 21: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA019226: AB_1845759, HPA031249: AB_2673807" "unprognostic (1.19e-1)" "unprognostic (2.41e-1)" "unprognostic (8.73e-3)" "unprognostic (1.57e-1)" "unprognostic (8.75e-2)" "unprognostic (4.30e-1)" "prognostic unfavorable (1.64e-4)" "unprognostic (1.27e-1)" "unprognostic (3.69e-2)" "unprognostic (3.04e-3)" "unprognostic (1.17e-2)" "unprognostic (1.45e-2)" "unprognostic (2.39e-2)" "unprognostic (1.67e-2)" "unprognostic (6.54e-3)" "unprognostic (1.94e-1)" "unprognostic (8.02e-3)" 11.2 13.9 14.6 9.7 15.6 2.3 17.4 17.4 20.3 14.7 15.4 18.9 14.4 17.0 21.9 15.2 15.4 11.0 16.4 14.8 15.0 15.3 12.0 11.1 10.0 14.5 14.8 21.0 11.1 21.1 14.4 10.9 14.8 13.5 20.0 18.3 13.4 12.3 13.9 11.0 19.3 15.9 14.9 9.4 14.1 19.8 14.4 11.0 14.9 16.6 9.1 12.4 11.6 16.4 29.3 18.5 35.5 40.2 28.5 28.5 21.3 43.8 33.6 35.4 39.7 14.9 17.1 15.1 19.9 33.4 62.4 27.9 35.2 26.3 33.1 15.4 28.7 13.7 20.9 28.7 26.6 14.6 10.5 26.9 21.0 39.3 42.4 21.1 29.6 13.7 46.8 6.9 29.7 18.5 11.8 29.2 81.0 34.6 21.8 16.5 24.9 17.4 33.0 24.4 48.1 52.3 32.7 46.6 44.1 38.9 41.3 27.6 21.3 17.7 34.3 23.8 35.5 22.1 50.3 34.9 22.1 34.6 56.2 21.6 6.4 8.6 9.9 6.8 11.0 16.1 12.8 15.2 7.1 16.2 22.7 16.6 0.7 10.7 5.1 10.6 15.5 7.9 14.6 15.6 17.4 20.3 14.8 15.0 14.5 14.8 14.8 14.9 14.4 16.4 2.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.2 0.0 0.0 0.0 0.0 15.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 12.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 5.1 0.1 0.0 0.0 0.0 YARS1 "tyrRS, YARS, YRS, YTS" ENSG00000134684 "Tyrosyl-tRNA synthetase 1" P54577 1 32775237-32817380 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 17.5;Cytotrophoblasts: 41.8;Extravillous trophoblasts: 48.1;Hofbauer cells: 41.0;Syncytiotrophoblasts: 37.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017936, HPA018950, HPA018954" Enhanced Enhanced Cytosol No No 1400000 "Cluster 48: NK-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA017936: AB_1858916, HPA018950: AB_1858919, HPA018954: AB_1858915" "unprognostic (4.05e-2)" "unprognostic (2.52e-1)" "unprognostic (4.21e-1)" "unprognostic (4.78e-2)" "unprognostic (9.54e-2)" "unprognostic (3.38e-3)" "prognostic unfavorable (6.97e-11)" "unprognostic (5.05e-2)" "unprognostic (6.29e-2)" "unprognostic (1.93e-1)" "unprognostic (1.81e-3)" "unprognostic (4.96e-2)" "prognostic unfavorable (1.02e-11)" "unprognostic (3.57e-3)" "unprognostic (1.02e-1)" "unprognostic (4.94e-2)" "prognostic unfavorable (6.57e-4)" 24.9 40.3 39.9 35.0 51.2 19.9 21.3 38.1 60.4 20.5 30.1 27.5 26.0 16.9 25.0 34.4 21.6 15.3 22.4 42.1 46.6 20.6 47.7 27.8 38.2 37.5 38.4 15.1 85.6 34.1 14.8 26.2 42.3 18.8 32.4 38.0 29.6 29.0 31.9 26.0 21.6 35.4 38.5 22.0 40.8 31.2 44.2 34.6 42.3 36.6 50.0 34.6 14.0 49.6 157.1 92.1 86.1 194.5 111.2 117.7 91.7 151.0 136.7 133.2 165.0 116.6 103.0 287.5 63.1 173.2 112.7 90.8 269.0 204.4 198.9 122.6 113.9 254.2 117.2 114.2 383.4 202.9 147.3 129.0 252.3 212.7 544.2 98.3 140.9 245.8 291.8 268.7 117.8 107.8 233.0 159.3 149.1 185.3 134.5 198.3 75.2 234.9 109.8 76.5 149.5 94.2 89.0 102.7 300.8 99.2 95.2 247.5 103.6 73.6 135.7 152.1 135.7 242.8 265.2 255.7 184.8 297.7 203.6 56.1 33.3 17.8 59.0 35.2 58.4 23.8 35.4 55.1 45.8 20.3 25.2 39.0 6.9 98.1 35.0 26.9 40.9 51.5 39.9 51.2 38.1 60.4 42.1 46.6 37.5 38.4 42.3 38.5 44.2 49.6 7.6 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.5 0.0 0.0 0.0 0.0 41.8 11.6 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 48.1 6.3 0.0 0.0 0.0 0.0 0.0 0.0 41.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 37.6 1.4 0.0 0.0 0.0 YBX3 "CSDA, CSDA1, dbpA, ZONAB" ENSG00000060138 "Y-box binding protein 3" P16989 12 10699089-10723323 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "skeletal muscle: 4915.7;tongue: 1635.6" "Cell type enhanced" "Detected in many" "Early spermatids: 1418.1;Prostatic glandular cells: 1553.4;Skeletal myocytes: 1316.7;Urothelial cells: 1339.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 6.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034838 Approved Supported Cytosol NA NA 230000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "HPA034838: AB_10670980" "unprognostic (1.93e-2)" "unprognostic (6.20e-2)" "unprognostic (3.56e-1)" "unprognostic (3.61e-2)" "unprognostic (4.15e-1)" "unprognostic (4.33e-2)" "unprognostic (1.10e-1)" "unprognostic (3.81e-2)" "unprognostic (2.91e-1)" "unprognostic (2.41e-1)" "unprognostic (3.23e-3)" "unprognostic (1.20e-1)" "prognostic unfavorable (6.17e-13)" "unprognostic (2.11e-2)" "unprognostic (1.51e-1)" "unprognostic (4.25e-2)" "unprognostic (2.44e-1)" 250.4 96.7 17.6 77.5 17.6 151.1 200.2 18.8 25.5 152.1 28.4 249.1 37.5 136.8 47.3 271.0 166.7 65.0 469.9 16.5 22.3 194.1 53.8 209.5 32.9 25.4 22.4 134.6 291.0 18.6 84.1 72.5 23.9 177.1 58.8 82.8 218.1 67.5 4915.7 358.1 99.0 100.9 20.9 79.5 149.7 265.7 22.2 36.7 136.1 1635.6 54.6 225.4 204.8 19.7 117.2 90.3 41.4 136.1 165.7 310.7 307.4 173.4 142.7 138.7 132.0 160.4 259.5 109.3 57.7 130.3 96.5 215.5 173.3 338.1 124.6 1.2 325.2 91.3 123.6 108.4 198.3 171.7 10.4 343.3 452.3 124.2 414.6 148.9 313.6 152.3 123.1 0.4 154.7 112.6 137.8 141.9 435.5 103.7 76.9 76.9 192.6 127.4 192.6 150.0 52.2 0.3 129.1 130.9 174.1 288.0 37.1 133.9 221.3 94.5 282.6 108.4 201.5 0.5 38.1 13.4 133.1 0.2 104.8 0.0 4.2 0.0 0.6 4.2 0.0 1.6 0.0 1.5 3.2 6.5 0.0 1.6 0.8 0.8 2.4 0.1 0.1 1.0 17.6 17.6 18.8 25.5 16.5 22.3 25.4 22.4 23.9 20.9 22.2 19.7 680.9 150.6 164.4 14.0 192.8 764.9 1226.9 212.9 552.7 36.1 288.8 292.7 497.7 105.8 177.8 145.3 89.6 145.7 39.2 94.3 133.1 125.3 1418.1 563.0 402.1 563.1 67.6 1081.5 2.4 143.3 84.3 484.8 119.8 551.3 63.3 291.0 235.6 23.1 97.7 16.8 1.0 139.5 120.1 223.2 494.7 470.2 264.7 292.2 259.7 21.5 83.9 67.2 2.1 4.5 0.1 122.0 76.3 223.8 80.6 1553.4 43.9 240.4 240.4 365.4 124.9 1316.7 643.1 594.6 158.4 638.6 1050.5 125.7 72.5 70.8 157.4 1339.7 YWHAB YWHAA ENSG00000166913 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta" P31946 20 44885702-44908532 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003759, HPA007925, HPA011212" Enhanced Supported Cytosol NA NA 97000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "CAB003759: AB_289588, HPA007925: AB_1844340, HPA011212: AB_1844334" "prognostic unfavorable (9.18e-4)" "unprognostic (1.48e-1)" "unprognostic (9.06e-2)" "prognostic unfavorable (5.46e-4)" "unprognostic (3.80e-1)" "prognostic unfavorable (6.14e-4)" "prognostic unfavorable (1.91e-6)" "prognostic unfavorable (6.01e-4)" "unprognostic (8.92e-2)" "unprognostic (2.01e-1)" "unprognostic (1.53e-2)" "unprognostic (2.35e-1)" "prognostic favorable (2.52e-5)" "unprognostic (6.72e-2)" "unprognostic (2.40e-1)" "unprognostic (6.60e-3)" "unprognostic (8.59e-2)" 133.1 120.6 214.6 140.0 225.1 111.1 106.8 156.3 275.9 103.7 155.9 160.8 128.4 102.0 83.5 148.3 97.6 97.6 105.0 232.0 221.6 155.6 96.7 126.4 174.3 187.5 175.4 81.2 58.1 123.1 48.3 123.2 187.7 99.9 173.5 114.9 83.8 133.4 85.7 129.9 135.3 142.6 174.1 162.3 123.5 56.8 201.5 139.1 118.1 78.6 210.3 153.5 91.6 195.0 306.5 227.8 179.5 173.2 291.0 255.5 238.9 270.8 263.2 327.7 284.6 479.6 336.9 324.2 272.6 361.9 355.5 315.5 256.1 506.0 388.0 124.1 153.1 242.4 180.8 285.8 192.6 396.8 223.6 201.4 370.4 257.2 328.4 223.6 333.5 196.0 265.6 152.6 340.9 363.2 312.1 325.3 169.7 348.9 341.6 240.3 259.5 251.1 352.3 336.6 189.8 202.6 459.9 485.7 331.1 207.7 354.6 376.3 381.2 504.6 259.7 288.8 281.2 100.4 196.9 292.5 369.9 260.8 263.5 105.5 95.2 90.5 71.3 130.8 74.0 71.2 89.3 87.7 102.8 66.5 70.6 86.2 93.4 72.4 155.4 65.9 113.8 71.9 214.6 225.1 156.3 275.9 232.0 221.6 187.5 175.4 187.7 174.1 201.5 195.0 421.4 253.2 289.0 35.6 292.8 276.7 256.0 270.8 195.2 239.9 229.6 199.3 197.1 200.1 236.5 248.3 50.1 358.6 317.2 532.6 230.9 476.1 17.7 183.0 274.2 351.5 298.1 183.4 93.8 489.8 627.7 246.4 192.7 278.5 227.9 262.8 300.9 155.9 410.3 292.7 64.1 388.4 160.7 394.5 329.9 24.2 188.9 418.7 222.3 51.5 543.5 229.0 295.5 25.6 63.0 654.9 429.9 210.3 301.8 419.0 328.9 364.5 206.4 131.5 230.1 173.3 337.8 51.1 171.3 333.3 325.3 531.3 369.3 394.2 382.4 440.5 YWHAE FLJ45465 ENSG00000108953 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon" P62258 17 1344275-1400222 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008445, CAB016200, CAB021109, CAB047350" Approved Supported Cytosol NA NA 83000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB016200: AB_626619, CAB021109: AB_10060396, CAB047350: , HPA008445: AB_1844336" "unprognostic (1.29e-1)" "unprognostic (1.50e-1)" "unprognostic (3.99e-2)" "prognostic favorable (6.48e-6)" "unprognostic (1.59e-1)" "unprognostic (2.91e-2)" "unprognostic (2.73e-2)" "unprognostic (4.77e-3)" "unprognostic (4.53e-2)" "unprognostic (5.14e-2)" "unprognostic (1.59e-1)" "unprognostic (2.73e-1)" "unprognostic (1.92e-3)" "unprognostic (8.33e-2)" "unprognostic (2.57e-1)" "unprognostic (3.24e-2)" "unprognostic (8.94e-2)" 221.9 198.9 251.8 122.8 264.2 121.3 198.7 266.3 272.8 168.8 195.7 161.1 136.8 155.6 192.7 239.1 188.1 103.7 242.3 260.7 275.4 229.3 211.7 176.9 113.7 271.1 246.8 170.8 154.9 236.9 178.8 198.2 267.1 150.0 168.1 220.8 184.8 121.6 656.7 193.3 129.3 137.3 279.2 101.5 136.9 165.4 262.2 211.0 208.5 441.8 164.5 186.9 179.7 302.7 615.3 565.8 700.2 563.4 376.9 454.7 589.8 382.1 481.5 724.5 571.3 907.5 305.5 524.7 411.9 621.9 439.7 463.1 859.2 745.6 798.7 294.2 930.9 334.1 366.2 409.4 483.4 277.1 311.1 421.6 458.6 619.3 897.0 520.6 729.2 458.5 402.8 337.9 719.7 368.5 445.8 264.1 566.6 596.9 332.7 477.3 255.9 380.4 547.7 365.7 354.2 497.2 531.1 240.3 364.3 439.9 442.3 290.9 467.4 411.9 293.8 453.7 731.4 190.5 329.9 346.6 478.4 387.5 585.4 78.6 137.2 41.2 47.3 153.6 57.8 78.1 67.3 55.1 180.3 59.1 55.7 51.2 49.9 64.1 144.8 133.8 99.7 151.0 251.8 264.2 266.3 272.8 260.7 275.4 271.1 246.8 267.1 279.2 262.2 302.7 363.6 298.1 194.4 83.2 161.1 573.9 457.5 468.4 281.7 153.6 313.6 219.1 473.4 265.9 310.9 371.5 50.1 463.2 128.7 300.7 745.4 460.8 258.0 573.6 414.3 352.6 352.6 244.7 73.4 421.4 709.5 319.4 194.7 502.7 211.5 328.1 262.3 309.0 384.9 111.0 72.4 346.3 376.4 260.9 434.9 434.3 280.8 227.5 425.2 60.0 320.5 357.8 55.6 56.8 112.1 464.8 289.8 294.9 279.5 487.9 272.1 707.8 504.6 173.3 243.3 361.2 524.6 508.7 573.3 333.8 586.6 519.5 130.7 287.2 361.1 474.4 YWHAG "14-3-3γ, 14-3-3GAMMA, PPP1R170" ENSG00000170027 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma" P61981 7 76326799-76358991 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 337.4;skeletal muscle: 349.8" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 408.8;Suprabasal keratinocytes: 425.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013274, CAB018389, HPA026918" Approved Approved Approved Cytosol NA NA 66000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 28: Keratinocytes - Keratinization" Cytosol "CAB013274: , CAB018389: AB_2217962, HPA026918: AB_10610566" "unprognostic (3.71e-2)" "prognostic unfavorable (4.53e-4)" "unprognostic (3.88e-2)" "unprognostic (1.25e-2)" "unprognostic (6.28e-3)" "unprognostic (2.40e-3)" "unprognostic (8.98e-3)" "prognostic unfavorable (5.34e-4)" "unprognostic (1.63e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (7.44e-4)" "unprognostic (3.03e-2)" "prognostic unfavorable (4.01e-4)" "unprognostic (9.31e-2)" "unprognostic (1.51e-1)" "unprognostic (2.45e-2)" "unprognostic (1.70e-1)" 188.1 99.2 165.6 60.6 185.3 27.3 61.0 80.2 337.4 41.1 8.5 48.4 47.8 50.9 20.8 64.5 37.9 54.5 111.4 206.5 206.1 50.8 72.4 47.1 43.2 204.5 120.7 40.7 59.7 50.1 32.6 55.4 192.9 46.1 44.0 87.2 39.9 40.0 349.8 43.7 41.6 66.4 81.5 44.2 38.2 28.9 135.1 40.2 29.7 238.4 48.6 78.8 46.3 199.1 189.0 231.9 200.5 256.7 200.5 114.9 90.5 213.3 105.0 129.6 139.5 147.0 196.7 263.5 71.7 190.8 215.2 171.6 254.3 235.8 180.5 179.9 110.9 250.2 150.0 164.5 182.6 309.0 234.0 127.1 221.0 151.5 310.8 137.3 208.9 140.2 349.9 289.0 195.8 177.6 222.3 227.1 223.0 150.7 160.4 256.3 203.0 291.7 204.5 126.3 107.0 297.1 236.7 299.2 156.0 256.9 208.5 184.2 222.6 250.7 145.7 225.4 290.1 95.1 191.6 399.5 225.5 285.3 273.8 1.5 2.3 0.5 0.8 2.0 1.4 1.3 1.0 1.1 2.4 0.7 0.7 0.9 0.5 0.5 1.8 2.6 0.9 0.9 165.6 185.3 80.2 337.4 206.5 206.1 204.5 120.7 192.9 81.5 135.1 199.1 73.7 32.1 26.4 23.2 51.8 408.8 128.3 87.9 126.9 102.9 107.0 70.1 234.0 40.0 55.1 38.6 12.5 36.5 39.3 49.9 37.2 52.4 91.2 96.0 82.9 92.0 85.4 72.8 99.9 38.2 84.1 97.4 61.2 127.9 67.3 38.7 50.0 93.1 83.5 124.5 78.5 35.7 44.7 90.3 229.0 25.2 46.3 87.8 94.3 40.3 64.2 27.1 20.6 23.1 57.1 71.1 29.9 43.2 56.6 129.8 34.1 61.3 47.2 35.3 32.9 92.5 91.5 13.4 19.0 160.1 425.4 67.2 41.5 46.4 45.1 177.1 Z83844.2 ENSG00000285304 "Novel protein" 22 37639693-37666932 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.8" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HL-60: 33.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA000757 Approved Approved Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 3: HMC-1 - Innate immune response" Cytosol "HPA000757: AB_1079951" 1.0 0.2 0.1 7.3 0.0 8.8 1.0 0.1 1.4 3.1 0.0 5.9 5.6 1.3 0.0 4.0 1.6 1.3 0.5 0.2 0.1 0.0 0.9 3.4 7.4 0.0 0.0 1.0 0.7 2.6 3.7 0.2 0.9 5.0 0.1 2.1 2.3 0.2 1.7 8.1 2.3 0.1 3.9 1.4 0.7 0.2 6.5 0.5 0.0 6.6 4.2 0.4 14.7 2.1 7.7 5.0 2.3 6.5 8.3 4.1 12.9 15.3 15.8 9.8 3.5 8.4 1.4 4.5 5.1 12.2 9.2 22.3 4.7 10.2 7.0 21.3 0.0 10.7 4.2 33.2 25.5 7.8 9.4 17.7 1.6 6.5 0.9 6.1 5.9 7.5 0.7 13.4 1.2 1.9 7.9 23.9 1.6 12.6 4.9 7.7 1.6 4.5 4.4 7.2 1.1 4.9 8.0 5.4 6.4 14.5 1.5 2.0 7.5 1.2 0.0 12.3 4.7 8.8 5.2 21.5 14.8 0.0 0.6 0.0 0.4 0.3 0.3 0.3 0.2 0.5 0.9 0.2 0.6 0.4 0.0 0.5 0.6 0.4 0.6 0.3 0.1 0.0 0.1 1.4 0.2 0.1 0.0 0.0 0.2 0.1 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZC3H15 LEREPO4 ENSG00000065548 "Zinc finger CCCH-type containing 15" Q8WU90 2 186486253-186509361 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031099, HPA031100, HPA031101" Enhanced Enhanced Cytosol NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Cytosol "HPA031099: AB_10599418, HPA031100: AB_2257403, HPA031101: AB_10611669" "unprognostic (1.51e-1)" "prognostic unfavorable (6.45e-5)" "unprognostic (2.24e-1)" "unprognostic (3.11e-3)" "unprognostic (5.92e-2)" "unprognostic (8.15e-2)" "prognostic unfavorable (1.48e-7)" "unprognostic (9.08e-3)" "unprognostic (4.95e-2)" "prognostic favorable (3.98e-4)" "prognostic unfavorable (9.75e-4)" "unprognostic (5.72e-3)" "unprognostic (5.69e-2)" "unprognostic (1.87e-1)" "unprognostic (1.82e-1)" "unprognostic (8.89e-2)" "unprognostic (3.45e-2)" 42.6 47.5 39.2 44.3 42.0 128.8 45.9 43.4 52.5 35.1 38.6 40.8 48.3 39.8 47.0 40.2 26.3 36.5 37.0 42.6 44.5 53.8 67.3 28.4 53.9 42.2 40.9 32.6 47.9 41.2 27.2 48.8 41.7 37.0 46.0 53.0 45.3 32.4 50.3 44.3 46.1 36.9 39.4 38.6 36.8 40.6 41.7 50.2 49.3 44.9 51.4 54.0 29.2 42.4 103.5 68.9 83.3 107.8 93.0 93.4 124.9 112.7 76.7 102.3 91.5 202.9 81.8 140.3 100.2 80.9 130.9 73.6 155.8 137.5 144.0 128.7 118.1 201.9 101.1 221.9 124.9 208.7 118.6 77.2 149.6 111.4 157.2 89.9 111.9 86.0 197.0 106.8 108.4 93.5 133.7 146.5 157.6 135.7 171.8 105.2 113.0 131.6 127.6 124.0 100.3 73.6 71.5 96.4 167.3 124.3 68.1 149.7 95.7 114.7 99.1 70.9 136.4 92.0 167.0 199.8 101.7 145.7 102.3 59.9 47.9 49.1 44.7 61.6 55.8 55.0 54.8 57.4 54.7 42.2 50.5 53.9 28.8 60.4 75.1 48.0 66.6 41.5 39.2 42.0 43.4 52.5 42.6 44.5 42.2 40.9 41.7 39.4 41.7 42.4 107.1 73.7 83.6 26.4 137.0 212.2 169.1 116.6 99.6 75.0 101.9 118.9 95.8 57.2 104.8 115.8 60.5 131.3 116.1 131.4 256.3 112.0 153.1 110.1 125.5 106.4 101.7 98.7 38.0 104.3 167.0 107.4 67.8 127.1 112.2 220.1 62.4 137.0 124.3 57.2 39.8 136.1 87.5 107.4 104.8 307.1 78.6 113.2 64.0 33.7 142.5 82.6 126.7 19.6 32.8 111.6 106.2 87.3 128.0 179.5 164.1 330.2 68.3 130.2 32.9 156.2 127.6 215.6 174.4 116.1 209.1 177.6 117.3 319.6 151.2 163.5 ZC3H7A "FLJ20318, HSPC055, ZC3H7, ZC3HDC7" ENSG00000122299 "Zinc finger CCCH-type containing 7A" Q8IWR0 16 11750586-11797258 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040808, HPA059849" Supported Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA040808: AB_10794150, HPA059849: AB_2684141" "unprognostic (2.82e-1)" "unprognostic (1.15e-1)" "unprognostic (1.45e-1)" "unprognostic (2.07e-1)" "unprognostic (5.64e-2)" "unprognostic (2.07e-2)" "unprognostic (5.75e-2)" "unprognostic (1.16e-2)" "unprognostic (4.96e-2)" "unprognostic (9.16e-2)" "unprognostic (1.44e-1)" "unprognostic (2.27e-2)" "unprognostic (7.27e-3)" "unprognostic (6.00e-2)" "unprognostic (1.05e-2)" "unprognostic (1.50e-2)" "unprognostic (3.55e-2)" 22.3 17.8 12.1 21.8 13.4 38.0 21.1 18.7 12.8 19.7 26.8 19.1 17.7 22.4 18.0 12.8 18.7 18.9 19.7 11.9 12.8 22.8 21.3 23.6 29.3 13.1 12.5 26.6 26.2 23.4 14.7 26.4 13.4 24.2 19.7 30.3 30.0 25.5 32.8 15.4 18.8 22.8 12.4 23.9 18.7 10.3 13.9 28.2 25.7 21.8 27.6 18.4 15.9 16.6 33.5 16.9 58.2 31.8 40.0 39.4 23.3 52.4 52.2 38.9 47.7 18.9 28.5 46.7 32.2 62.7 25.0 21.1 33.1 50.9 56.0 36.9 37.5 20.1 35.5 31.8 56.6 46.5 42.4 44.7 27.7 36.7 68.7 45.4 49.5 41.8 33.5 40.8 57.1 26.2 35.3 23.6 34.2 23.2 15.2 51.0 32.6 33.3 36.0 25.6 44.3 35.2 42.5 40.5 52.4 34.3 29.6 30.2 47.2 45.1 27.6 61.9 35.8 32.5 26.2 68.5 33.3 34.3 118.7 16.6 12.9 20.4 14.0 17.8 19.8 15.5 18.1 15.4 12.8 16.5 21.1 15.0 16.0 22.3 32.2 10.2 24.2 9.4 12.1 13.4 18.7 12.8 11.9 12.8 13.1 12.5 13.4 12.4 13.9 16.6 39.4 64.1 36.4 36.9 46.2 15.0 15.2 9.6 27.3 29.4 21.2 23.7 44.3 17.2 29.0 14.7 54.2 14.9 40.5 16.4 15.6 18.5 3.2 30.9 48.7 32.7 20.9 22.5 29.4 22.7 15.4 31.1 27.5 33.9 18.3 31.3 32.9 18.5 14.5 53.8 35.3 25.1 18.3 36.3 26.2 5.3 32.6 39.3 19.6 30.9 40.2 25.6 22.6 65.9 32.7 22.3 16.9 35.7 45.2 18.0 20.3 16.4 29.5 52.4 19.7 42.2 37.1 17.2 9.0 18.0 15.8 7.5 40.3 28.9 18.5 16.0 ZC3H7B "DKFZp434K0920, FLJ13787, KIAA1031, RoXaN" ENSG00000100403 "Zinc finger CCCH-type containing 7B" Q9UGR2 22 41301525-41360147 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001784, HPA076092" Uncertain Supported Cytosol NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" Cytosol "HPA001784: AB_1080637, HPA076092: " "unprognostic (1.71e-1)" "unprognostic (1.68e-1)" "unprognostic (3.49e-2)" "unprognostic (3.53e-2)" "unprognostic (3.35e-2)" "unprognostic (5.66e-2)" "unprognostic (3.73e-2)" "unprognostic (7.92e-2)" "unprognostic (7.12e-2)" "unprognostic (7.73e-2)" "unprognostic (1.39e-2)" "unprognostic (3.19e-1)" "prognostic favorable (5.43e-7)" "unprognostic (1.43e-2)" "unprognostic (2.92e-2)" "unprognostic (4.81e-2)" "unprognostic (2.89e-1)" 29.5 42.9 37.5 20.2 37.1 16.0 22.9 31.9 43.4 25.6 15.1 25.8 24.3 31.1 13.5 20.3 27.2 17.2 26.1 34.1 38.7 31.4 42.1 26.9 21.4 56.0 35.7 41.3 30.9 44.5 30.5 18.5 58.8 26.0 13.2 17.9 44.9 26.7 24.9 20.0 25.9 20.7 30.2 25.6 24.8 11.6 37.2 25.2 45.9 19.1 15.2 23.5 19.7 36.0 59.0 32.2 42.0 25.6 37.6 33.9 49.1 65.8 69.6 53.8 42.1 35.3 23.8 33.1 79.1 92.0 30.1 39.1 35.7 61.8 27.4 76.0 58.9 29.6 40.2 45.4 50.4 57.4 24.9 42.7 34.6 46.3 56.4 45.7 58.9 25.7 60.4 17.9 46.0 59.1 45.4 29.7 30.3 44.2 24.1 68.7 26.4 37.8 45.9 41.5 27.1 20.3 60.5 36.6 31.5 29.0 24.1 38.1 119.0 52.5 54.4 16.3 40.8 30.8 18.4 33.2 44.0 28.0 46.1 0.0 0.1 0.1 0.1 0.0 0.1 0.3 0.2 0.1 0.0 0.3 0.2 0.1 0.0 0.3 0.0 0.2 0.1 0.0 37.5 37.1 31.9 43.4 34.1 38.7 56.0 35.7 58.8 30.2 37.2 36.0 15.4 12.8 22.2 14.4 13.1 7.1 12.7 13.4 10.2 22.4 18.2 15.6 10.1 20.0 15.7 22.0 18.8 9.0 11.3 13.5 7.9 14.0 0.9 14.2 25.8 17.9 33.6 7.8 20.1 13.3 9.0 16.4 11.2 16.9 8.2 59.0 19.2 44.0 12.0 42.1 20.6 14.6 26.4 12.9 9.8 3.1 33.2 8.2 12.4 13.1 15.2 9.8 20.6 19.1 17.6 18.8 8.1 29.0 7.4 21.2 23.0 18.5 11.7 22.2 19.7 23.1 18.0 2.0 4.9 8.9 5.8 6.2 11.1 46.9 17.1 14.8 ZC3HAV1L "C7orf39, MGC14289" ENSG00000146858 "Zinc finger CCCH-type containing, antiviral 1 like" Q96H79 7 139025706-139036042 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 5.6;Gastric mucus-secreting cells: 4.6;Microglial cells: 9.4;Oligodendrocyte precursor cells: 5.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 11 "basophil: 10.2" "Lineage enriched" "Detected in single" 11 "granulocytes: 10.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA020386, HPA050741" Uncertain Enhanced Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "HPA020386: AB_2257412, HPA050741: AB_2681224" "unprognostic (1.12e-1)" "prognostic unfavorable (7.35e-4)" "unprognostic (3.07e-2)" "unprognostic (1.50e-1)" "unprognostic (6.99e-2)" "unprognostic (1.31e-1)" "unprognostic (1.62e-2)" "unprognostic (8.51e-2)" "unprognostic (3.34e-3)" "unprognostic (2.07e-1)" "unprognostic (3.44e-2)" "unprognostic (2.00e-2)" "unprognostic (1.49e-3)" "unprognostic (5.04e-2)" "unprognostic (2.88e-1)" "unprognostic (1.84e-2)" "unprognostic (3.08e-3)" 3.1 3.7 2.2 2.6 2.8 1.3 3.4 0.0 2.1 3.3 9.9 2.3 3.2 6.7 2.2 4.3 4.9 3.2 2.6 3.3 3.8 2.8 0.8 2.5 2.5 1.4 1.2 9.3 1.8 2.3 1.6 9.5 0.9 3.9 3.2 0.5 2.6 4.3 1.7 8.7 2.6 5.2 0.6 4.6 2.8 2.0 4.4 2.9 8.3 1.6 3.0 2.7 2.8 1.0 14.9 11.9 8.6 28.8 7.1 10.8 0.4 7.2 3.2 5.3 7.3 19.9 8.4 0.4 10.1 7.8 0.0 10.5 12.1 3.0 16.0 8.8 0.1 19.0 12.6 6.8 5.7 0.1 6.6 8.3 4.6 7.9 3.7 0.3 9.1 9.3 8.3 0.5 10.9 0.1 20.4 11.4 1.5 2.0 7.4 21.1 29.2 0.2 4.9 7.9 5.8 26.1 17.7 2.5 10.6 1.7 10.9 7.7 12.7 9.5 8.5 3.2 0.1 0.5 0.1 0.3 5.3 0.1 9.0 10.2 0.1 0.9 0.1 0.1 0.2 0.4 0.3 0.2 0.1 0.9 0.2 0.2 0.4 0.2 0.1 0.2 0.2 0.2 2.2 2.8 0.0 2.1 3.3 3.8 1.4 1.2 0.9 0.6 4.4 1.0 2.4 0.0 0.0 1.6 0.1 0.4 0.9 0.2 2.8 0.3 0.8 1.7 0.5 0.0 0.1 0.0 0.0 1.2 0.1 0.2 0.0 0.2 0.0 1.4 4.4 1.6 0.0 3.8 5.6 0.0 1.6 2.0 4.6 0.8 4.5 3.0 1.1 0.0 0.9 0.0 2.3 0.0 0.0 0.3 0.3 0.0 1.8 0.5 0.0 9.4 0.0 0.6 0.0 5.5 0.2 0.2 0.0 1.5 1.5 0.6 0.0 0.3 0.1 0.0 0.0 0.9 2.3 0.0 0.6 2.9 1.0 0.7 0.2 3.8 0.2 0.5 ZDHHC1 "C16orf1, HSU90653, ZNF377" ENSG00000159714 "Zinc finger DHHC-type containing 1" Q8WTX9 16 67394152-67416833 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 84.6;Late spermatids: 53.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.4;non-classical monocyte: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 11.4;ASC TERT1: 11.3;U-138 MG: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042531, HPA048659" Uncertain Approved Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA042531: AB_2678041, HPA048659: AB_2680483" "unprognostic (8.96e-2)" "unprognostic (1.43e-2)" "unprognostic (1.05e-3)" "prognostic favorable (1.25e-6)" "unprognostic (1.68e-2)" "unprognostic (9.33e-2)" "unprognostic (6.03e-2)" "unprognostic (1.82e-2)" "unprognostic (1.93e-1)" "unprognostic (2.67e-1)" "prognostic favorable (5.99e-4)" "unprognostic (2.17e-1)" "prognostic favorable (1.55e-6)" "unprognostic (2.10e-1)" "unprognostic (1.59e-1)" "unprognostic (1.46e-1)" "unprognostic (5.63e-3)" 17.7 10.9 3.7 1.8 3.5 0.2 17.9 3.2 5.6 27.1 7.4 14.5 2.3 21.7 3.9 6.8 22.4 6.3 10.8 3.4 4.2 19.3 4.4 12.4 1.4 4.9 6.7 23.6 17.7 7.8 20.4 3.1 4.1 19.5 1.7 0.8 17.0 6.7 10.7 19.1 7.4 3.9 4.7 14.9 10.6 20.3 4.4 0.6 29.4 3.0 0.8 12.8 16.3 2.8 5.2 6.0 1.4 7.3 11.4 11.3 0.0 3.2 9.0 2.6 2.8 0.0 2.6 0.0 1.3 4.2 2.5 3.3 0.4 0.6 0.5 1.6 4.6 0.5 0.1 0.4 5.2 0.2 4.0 6.0 5.3 2.7 0.6 6.0 3.3 0.0 0.0 0.0 1.8 0.3 0.0 0.0 2.9 1.8 0.1 0.0 0.0 0.0 3.5 2.9 2.1 7.4 0.5 0.1 6.5 0.4 1.9 1.1 5.8 11.7 2.0 5.6 3.3 1.4 0.3 0.0 7.2 0.1 4.7 0.0 1.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.3 3.7 3.5 3.2 5.6 3.4 4.2 4.9 6.7 4.1 4.7 4.4 2.8 7.0 0.0 0.0 10.4 0.9 7.1 6.7 1.3 10.8 2.2 7.5 7.0 1.1 10.0 1.4 7.3 4.2 2.0 0.3 5.2 9.8 3.4 29.3 84.6 10.9 5.2 9.0 0.4 5.7 4.0 0.2 13.6 8.6 7.3 0.0 8.5 6.1 2.0 2.0 3.3 5.0 12.9 2.0 16.4 6.8 53.0 14.6 9.3 5.4 2.8 8.2 7.9 1.0 4.0 2.5 2.2 4.9 10.9 0.7 7.2 2.0 6.6 5.5 0.5 0.0 5.1 9.4 12.4 8.6 6.2 7.1 5.7 0.7 10.4 6.8 4.8 ZER1 "C9orf60, Hzyg, ZYG, ZYG11BL" ENSG00000160445 "Zyg-11 related cell cycle regulator" Q7Z7L7 9 128729786-128772414 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 67.7;Inhibitory neurons: 61.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048464 Approved Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA048464: AB_2756306" "unprognostic (1.37e-1)" "prognostic favorable (1.18e-6)" "unprognostic (9.11e-3)" "unprognostic (2.36e-2)" "unprognostic (7.46e-2)" "unprognostic (9.35e-2)" "unprognostic (2.18e-1)" "unprognostic (4.81e-3)" "unprognostic (3.65e-1)" "unprognostic (4.90e-3)" "unprognostic (6.65e-3)" "unprognostic (1.69e-1)" "prognostic favorable (5.15e-11)" "unprognostic (5.77e-2)" "unprognostic (1.31e-1)" "unprognostic (7.71e-2)" "unprognostic (1.14e-1)" 24.3 31.0 57.4 12.4 56.4 17.1 23.8 28.3 72.8 26.7 23.2 38.9 33.3 29.8 13.1 28.6 25.9 17.4 44.1 59.7 48.2 26.5 22.9 19.9 13.9 44.6 40.1 28.1 26.6 31.9 33.5 15.9 44.8 31.7 13.0 17.3 27.4 24.7 72.0 33.8 31.5 16.4 28.5 19.6 26.9 36.6 43.8 19.2 26.5 43.6 11.3 31.0 24.7 46.1 17.3 19.1 12.4 17.0 36.4 24.9 34.3 16.7 28.4 22.6 18.1 17.3 19.6 10.6 18.1 29.3 16.9 37.1 13.8 24.8 9.5 21.2 17.7 7.0 34.2 12.4 28.3 11.1 20.1 31.1 36.6 22.9 16.1 30.6 19.5 21.2 13.7 22.9 15.5 65.9 20.9 12.5 12.3 24.6 24.4 18.6 15.6 41.4 16.8 23.4 23.7 17.9 26.7 35.4 18.9 14.4 52.0 12.7 22.2 18.4 7.8 23.5 10.2 28.7 29.3 8.6 27.2 6.6 13.5 11.5 3.2 8.8 4.4 4.7 6.0 3.0 4.7 5.7 3.3 3.8 4.9 4.7 13.6 5.1 5.2 4.9 4.7 5.0 57.4 56.4 28.3 72.8 59.7 48.2 44.6 40.1 44.8 28.5 43.8 46.1 10.7 12.8 16.8 33.0 8.0 2.8 2.9 5.2 6.2 20.2 13.0 12.6 22.6 4.3 4.7 5.5 14.6 4.8 4.8 41.7 1.9 5.8 7.1 15.2 8.6 9.0 7.2 17.9 67.7 9.6 2.5 8.6 13.7 11.8 10.2 12.0 7.1 13.0 6.2 21.9 61.2 15.0 2.0 4.4 1.0 2.4 11.1 5.7 8.8 16.9 9.5 9.8 6.2 23.1 48.9 7.1 23.2 10.5 8.7 6.4 25.4 13.8 13.5 13.4 13.1 9.2 9.1 10.6 3.5 8.0 5.8 8.5 7.1 16.0 9.6 3.4 ZFP30 "KIAA0961, ZNF745" ENSG00000120784 "ZFP30 zinc finger protein" Q9Y2G7 19 37613749-37692337 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 60.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-2 OS: 32.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030606 Uncertain Approved Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol "HPA030606: AB_10602684" "unprognostic (1.86e-2)" "unprognostic (3.00e-2)" "unprognostic (1.09e-3)" "unprognostic (3.64e-2)" "unprognostic (6.10e-3)" "unprognostic (1.14e-2)" "unprognostic (1.96e-2)" "unprognostic (1.75e-1)" "unprognostic (5.62e-3)" "unprognostic (7.03e-2)" "unprognostic (2.72e-2)" "unprognostic (5.96e-2)" "prognostic favorable (3.86e-4)" "unprognostic (3.01e-1)" "unprognostic (4.92e-2)" "unprognostic (1.24e-2)" "unprognostic (1.09e-3)" 2.7 3.7 2.2 2.1 3.4 1.1 4.8 8.5 3.4 3.2 0.8 3.0 2.3 4.5 3.8 3.4 4.1 2.6 2.7 2.3 2.9 3.4 2.3 3.1 4.0 1.7 2.1 5.1 3.6 5.8 1.1 4.4 2.0 4.4 2.9 8.7 2.6 4.3 3.0 5.4 2.0 3.5 2.0 4.1 3.2 7.3 2.4 4.6 6.1 3.9 3.8 2.4 1.1 4.7 9.4 8.1 12.9 18.2 6.8 6.6 3.9 9.5 8.7 7.0 7.6 6.5 1.7 0.0 9.5 8.7 5.7 3.4 12.9 5.0 7.5 14.2 5.0 9.4 10.0 5.0 5.1 1.3 7.0 6.0 7.6 6.1 9.1 5.6 4.1 6.4 7.2 0.0 9.1 4.3 10.3 4.8 2.8 1.2 5.5 4.0 16.8 0.1 4.3 15.3 14.4 15.6 11.1 4.3 3.4 5.1 5.9 2.5 9.0 9.5 32.5 4.6 9.6 4.9 5.5 5.9 0.0 0.1 7.3 2.2 0.5 1.3 1.1 0.6 1.5 0.5 1.4 1.1 0.4 2.1 1.7 1.8 0.3 2.8 0.2 0.9 1.1 1.0 2.2 3.4 8.5 3.4 2.3 2.9 1.7 2.1 2.0 2.0 2.4 4.7 4.6 6.4 1.8 9.8 6.7 0.8 1.2 1.5 2.8 11.4 2.6 2.5 7.3 4.3 2.7 3.7 4.2 2.6 3.0 1.4 1.9 3.4 60.5 3.5 5.5 6.3 4.2 1.7 17.6 2.3 1.6 5.1 4.6 3.6 9.5 7.3 3.6 0.9 2.5 8.4 19.1 3.1 0.0 2.1 1.1 14.3 7.5 2.4 0.0 11.2 1.6 4.8 5.2 20.1 17.5 1.8 0.8 6.4 1.4 1.8 0.6 2.8 3.2 9.2 6.6 5.4 4.6 9.4 5.2 2.9 0.4 0.8 4.0 4.1 2.2 0.7 ZGRF1 "C4orf21, FLJ11331" ENSG00000138658 "Zinc finger GRF-type containing 1" Q86YA3 4 112539333-112636995 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 18.0;Microglial cells: 17.8;Oligodendrocytes: 27.5;Spermatocytes: 22.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA030704, HPA030706" Uncertain Approved Cytosol NA Yes "Cluster 7: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA030704: AB_2673577, HPA030706: AB_10601784" "unprognostic (8.48e-2)" "unprognostic (6.17e-2)" "unprognostic (9.51e-2)" "unprognostic (1.53e-1)" "unprognostic (1.10e-1)" "unprognostic (1.84e-3)" "unprognostic (5.83e-3)" "unprognostic (1.45e-1)" "unprognostic (5.89e-4)" "unprognostic (4.74e-2)" "unprognostic (4.30e-2)" "unprognostic (3.72e-3)" "unprognostic (7.60e-10)" "unprognostic (3.45e-2)" "unprognostic (2.93e-1)" "unprognostic (1.15e-1)" "unprognostic (2.02e-4)" 1.0 0.7 0.9 2.0 1.4 7.8 1.3 2.2 1.5 0.9 0.1 1.1 1.2 1.2 0.3 1.0 0.8 0.5 0.7 0.8 0.7 0.5 0.6 0.9 2.5 1.3 0.9 1.1 0.7 0.3 1.3 1.7 1.3 0.9 1.4 4.3 0.9 0.4 1.2 1.4 1.5 0.9 1.0 1.8 0.9 3.6 1.0 5.2 0.8 0.6 2.9 0.7 0.8 2.1 5.0 3.6 12.1 8.6 0.9 1.6 4.7 8.8 3.7 8.7 7.8 6.9 7.3 13.2 2.5 2.7 3.6 4.0 12.7 4.7 10.0 7.3 3.1 8.3 5.8 2.1 0.4 18.5 5.3 0.8 0.6 11.0 3.0 1.2 3.5 13.6 12.0 14.3 6.0 8.2 25.0 6.7 6.3 5.2 4.2 13.8 18.1 4.5 1.5 4.4 5.6 9.5 3.9 5.3 1.7 8.8 2.5 5.4 4.2 10.9 10.6 5.9 7.1 5.5 10.1 17.0 4.9 6.3 6.3 0.0 0.1 0.3 0.2 0.7 0.1 0.3 0.1 0.0 0.0 0.5 0.4 0.4 0.2 0.2 0.1 0.7 0.2 0.1 0.9 1.4 2.2 1.5 0.8 0.7 1.3 0.9 1.3 1.0 1.0 2.1 3.3 0.0 1.3 10.4 5.4 0.0 1.3 0.0 0.6 10.4 2.1 1.7 2.4 0.0 3.7 1.8 8.4 3.5 10.4 2.1 0.0 1.0 2.9 1.8 3.5 1.9 1.2 11.1 18.0 0.5 2.7 2.3 4.6 2.8 2.5 12.2 1.1 0.6 1.8 5.0 14.5 1.8 0.0 1.6 0.0 2.8 0.6 4.1 0.0 17.8 1.3 1.6 6.2 17.6 27.5 0.6 1.4 2.2 10.5 0.8 0.7 0.3 0.7 17.6 0.0 3.1 2.7 22.1 15.6 3.6 0.0 0.8 5.0 2.2 2.5 0.9 ZNF135 "pHZ-17, ZNF61, ZNF78L1" ENSG00000176293 "Zinc finger protein 135" P52742 19 58059239-58086310 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 21.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 5.5;HSkMC: 5.5;MOLT-4: 6.3;NTERA-2: 5.5;T-47d: 7.0" "Low region specificity" "Detected in all" HPA006961 Approved Approved Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Cytosol "HPA006961: AB_1080670" "unprognostic (4.87e-2)" "unprognostic (7.58e-2)" "unprognostic (6.53e-2)" "unprognostic (2.96e-1)" "unprognostic (1.01e-1)" "unprognostic (6.54e-2)" "unprognostic (1.70e-1)" "unprognostic (5.85e-2)" "unprognostic (9.18e-3)" "unprognostic (1.20e-2)" "unprognostic (1.01e-3)" "unprognostic (2.34e-1)" "prognostic favorable (3.93e-5)" "unprognostic (2.39e-2)" "unprognostic (1.93e-1)" "unprognostic (1.64e-1)" "unprognostic (1.25e-1)" 3.6 2.5 5.2 2.1 5.1 1.3 6.2 3.8 5.0 6.5 4.3 4.6 1.3 8.7 7.9 2.7 6.2 4.2 3.5 4.4 5.2 6.2 0.8 2.7 2.2 4.7 4.3 11.4 2.3 10.6 8.3 3.9 4.5 6.0 2.0 10.0 2.3 5.2 2.0 4.6 2.1 6.8 3.0 3.9 2.6 6.5 4.9 7.1 8.0 1.8 2.3 4.8 3.8 7.8 0.0 0.0 1.4 0.0 0.1 0.0 0.0 3.3 0.0 4.3 0.2 0.0 0.2 0.0 3.6 4.7 2.6 0.2 0.0 0.0 4.7 0.0 5.1 0.0 0.0 0.0 1.9 0.0 5.5 5.5 0.0 2.5 0.0 0.1 0.0 0.0 0.0 0.0 3.2 0.0 6.3 0.0 5.5 0.0 0.0 0.0 0.0 0.0 2.2 3.8 5.2 0.1 0.0 0.0 0.0 4.8 7.0 0.0 0.0 0.0 2.9 0.0 0.0 0.2 2.3 0.0 0.0 0.0 2.6 0.0 0.0 1.9 0.0 0.1 0.0 0.4 0.1 0.1 0.8 1.7 1.7 1.0 0.0 2.6 0.0 2.0 0.1 0.4 5.2 5.1 3.8 5.0 4.4 5.2 4.7 4.3 4.5 3.0 4.9 7.8 2.7 0.0 1.1 5.5 3.2 2.3 2.5 0.8 2.8 11.9 7.9 7.6 5.3 11.5 1.2 9.2 16.7 0.9 0.8 0.1 21.5 6.4 13.3 7.8 5.6 3.3 2.4 1.7 8.1 0.7 0.2 4.1 0.0 3.6 5.1 12.3 4.2 0.3 0.6 15.2 9.3 1.2 2.0 0.3 0.3 11.5 7.8 0.5 1.8 1.9 0.3 8.0 1.0 6.0 13.7 0.6 0.3 6.8 0.0 2.1 0.2 2.5 4.2 14.0 0.0 3.3 5.3 12.7 11.5 1.0 3.1 0.7 1.0 4.6 0.9 1.6 ZNF23 "KOX16, Zfp612, ZNF359, ZNF612" ENSG00000167377 "Zinc finger protein 23" P17027 16 71447597-71463095 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 15.0;Excitatory neurons: 10.0;Inhibitory neurons: 11.2;Oligodendrocyte precursor cells: 13.0;Oligodendrocytes: 16.0;Respiratory ciliated cells: 9.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023534 Uncertain Approved Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 59: Non-specific - Transcription" Cytosol "HPA023534: AB_1859140" "unprognostic (8.49e-2)" "unprognostic (1.46e-2)" "unprognostic (1.89e-1)" "unprognostic (1.74e-1)" "unprognostic (3.98e-2)" "unprognostic (1.28e-1)" "unprognostic (1.73e-1)" "unprognostic (1.29e-1)" "unprognostic (9.89e-3)" "unprognostic (2.12e-1)" "unprognostic (8.37e-3)" "unprognostic (2.19e-2)" "unprognostic (2.62e-3)" "unprognostic (3.65e-1)" "unprognostic (6.94e-2)" "unprognostic (9.59e-2)" "unprognostic (6.04e-2)" 5.5 4.3 8.6 5.3 8.4 4.4 6.2 8.8 9.9 5.8 8.9 5.6 2.8 6.9 8.0 4.2 7.1 3.6 5.1 8.6 8.5 5.6 5.4 5.4 6.2 8.4 8.3 8.2 4.6 5.4 14.3 4.7 8.1 5.3 5.7 16.9 4.3 5.8 6.5 5.8 5.0 6.9 8.2 5.7 4.1 6.9 8.6 4.9 7.5 7.1 6.0 4.2 3.5 9.8 7.8 4.7 12.0 8.8 7.6 6.6 7.8 17.1 15.9 11.7 8.6 6.1 7.6 15.1 4.2 13.1 11.4 4.7 7.9 10.2 13.7 4.0 5.2 6.7 5.0 6.5 9.2 12.3 5.7 10.7 9.0 12.1 18.6 10.9 4.1 7.9 11.1 2.9 12.5 13.0 6.4 6.0 13.4 4.0 3.9 3.3 5.3 4.6 7.7 6.4 9.9 12.8 5.5 3.9 5.3 7.5 5.1 6.4 11.5 21.2 7.2 5.9 10.7 6.5 10.6 19.8 16.0 6.2 13.2 0.8 0.8 0.5 1.9 1.8 1.8 1.3 1.0 2.1 1.1 2.7 2.1 1.5 0.0 2.6 1.0 1.9 1.9 0.9 8.6 8.4 8.8 9.9 8.6 8.5 8.4 8.3 8.1 8.2 8.6 9.8 0.6 6.4 2.3 15.0 2.6 0.3 0.3 0.2 2.8 2.6 0.7 0.6 0.4 0.0 3.2 0.0 6.2 0.2 0.4 0.5 1.9 2.0 0.2 1.0 1.0 1.1 0.0 7.8 10.0 1.0 0.3 0.9 1.5 0.5 2.5 1.3 1.1 0.5 0.4 3.3 11.2 1.0 0.0 0.3 0.3 0.0 0.6 0.5 0.0 6.5 0.4 1.4 2.1 13.0 16.0 1.5 1.4 0.0 1.5 0.3 0.7 0.3 9.2 3.3 0.0 0.7 0.9 1.5 1.4 2.3 0.0 0.0 1.4 0.5 1.5 0.1 ZNF268 HZF3 ENSG00000090612 "Zinc finger protein 268" Q14587 12 133181409-133214832 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001794 Approved Supported Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 1: Thyroid gland - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" Cytosol "HPA001794: AB_2666437" "unprognostic (7.65e-2)" "unprognostic (2.78e-1)" "unprognostic (1.21e-1)" "unprognostic (4.64e-2)" "unprognostic (3.09e-1)" "unprognostic (2.81e-1)" "unprognostic (1.16e-1)" "unprognostic (1.94e-1)" "unprognostic (4.91e-3)" "unprognostic (2.21e-1)" "unprognostic (7.63e-3)" "unprognostic (2.57e-2)" "unprognostic (6.59e-3)" "unprognostic (5.69e-2)" "unprognostic (2.30e-1)" "unprognostic (8.79e-2)" "unprognostic (1.53e-3)" 5.6 6.6 2.8 4.0 3.9 3.6 9.5 5.0 3.9 7.4 4.9 5.5 4.4 7.5 7.4 6.5 8.7 4.3 4.4 2.7 3.3 9.3 12.8 5.6 6.2 3.4 3.5 9.7 5.3 13.1 3.9 9.5 3.3 8.1 5.4 12.0 5.6 6.9 2.4 5.1 5.2 5.8 3.2 6.0 7.1 5.8 3.2 7.3 10.7 4.9 7.1 6.3 3.7 4.2 6.9 10.1 21.4 19.0 9.0 11.5 14.6 10.2 10.8 9.3 7.4 10.6 4.6 5.9 15.5 10.3 9.4 6.3 10.5 12.8 11.8 0.2 8.5 14.6 5.3 13.4 9.6 14.1 12.6 16.9 12.6 11.1 17.4 12.5 10.8 5.6 11.2 7.8 15.9 8.2 5.7 6.4 15.8 8.7 0.6 5.7 6.6 7.3 5.3 15.9 15.3 12.9 20.9 7.0 9.1 18.2 17.0 12.0 11.6 10.6 13.2 3.7 9.3 2.8 4.2 12.9 5.9 7.3 11.3 1.9 5.1 6.0 8.2 5.0 5.5 9.6 9.3 10.4 7.6 7.2 14.2 10.2 1.6 10.8 8.6 6.0 5.2 5.0 2.8 3.9 5.0 3.9 2.7 3.3 3.4 3.5 3.3 3.2 3.2 4.2 8.0 19.2 22.3 6.8 10.0 1.8 5.6 5.7 5.2 24.3 10.0 8.4 8.4 12.8 13.6 7.3 20.9 14.9 3.2 2.8 5.9 8.8 15.5 7.1 9.0 9.5 3.6 15.8 8.4 6.4 9.4 9.7 4.6 7.5 2.5 19.1 14.6 11.0 9.8 21.9 10.0 6.9 4.1 6.7 3.0 4.3 10.5 7.7 5.4 10.3 5.5 15.8 8.2 11.6 12.9 7.7 7.6 11.3 5.2 6.3 5.5 11.5 7.1 19.1 6.6 17.4 8.8 14.9 17.3 6.4 2.8 8.6 7.5 12.4 6.9 4.4 ZNF70 "Cos17, MGC48959" ENSG00000187792 "Zinc finger protein 70" Q9UC06 22 23738682-23751112 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 10.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA018821 Uncertain Approved Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 14: REH - Unknown function" "Cluster 52: Non-specific - Transcription" Cytosol "HPA018821: AB_1859423" "unprognostic (3.17e-2)" "unprognostic (2.31e-1)" "unprognostic (2.78e-1)" "unprognostic (8.49e-3)" "unprognostic (1.08e-1)" "unprognostic (2.80e-2)" "unprognostic (6.07e-3)" "unprognostic (2.18e-3)" "unprognostic (9.93e-2)" "unprognostic (6.20e-2)" "unprognostic (1.73e-2)" "unprognostic (3.69e-2)" "unprognostic (1.95e-2)" "unprognostic (6.72e-2)" "unprognostic (2.40e-1)" "unprognostic (4.36e-2)" "unprognostic (5.69e-2)" 1.4 1.2 1.0 1.3 1.4 1.6 1.3 2.8 1.1 1.9 2.2 1.4 0.8 1.9 2.3 0.8 1.9 1.1 1.6 0.9 1.0 1.0 0.7 1.2 1.4 2.0 1.4 3.9 1.8 2.1 1.6 1.2 1.1 1.5 1.2 3.0 2.0 1.5 2.6 1.1 1.2 1.6 0.8 1.4 1.3 1.2 1.6 1.2 1.8 2.1 1.6 1.4 1.3 2.5 1.2 1.5 2.9 3.0 4.2 2.0 0.9 1.1 2.2 2.5 3.5 1.5 0.8 1.7 0.7 2.4 1.6 1.3 2.0 1.5 3.1 1.1 1.8 3.3 3.0 1.3 2.5 3.0 2.7 2.0 0.9 3.3 2.7 3.2 2.0 1.3 1.2 2.4 1.8 1.6 1.7 1.4 0.7 1.1 0.6 7.2 2.8 0.4 0.9 1.6 1.6 2.0 1.6 2.0 1.2 2.0 1.0 1.4 2.6 2.7 3.4 1.8 1.2 2.4 0.4 1.5 2.4 1.3 2.4 1.5 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.1 0.1 0.3 0.2 0.3 0.8 0.5 0.2 0.4 0.1 0.1 1.0 1.4 2.8 1.1 0.9 1.0 2.0 1.4 1.1 0.8 1.6 2.5 1.2 0.0 2.8 0.7 1.0 0.4 1.1 0.0 1.2 3.8 1.1 1.4 2.6 2.8 1.8 3.7 10.4 0.4 2.1 0.3 0.0 1.1 1.4 1.6 3.9 1.7 1.2 0.8 0.8 1.1 0.6 3.2 0.5 1.0 1.3 3.8 4.2 0.5 0.8 6.7 1.2 0.6 0.0 1.6 0.6 3.3 6.2 1.0 0.0 0.0 0.8 2.1 0.0 0.0 1.6 0.4 0.0 4.1 1.5 0.7 0.8 0.9 3.6 4.0 6.6 5.4 2.7 2.7 2.5 1.0 0.0 0.3 1.2 2.8 0.7 0.9 ZNF764 MGC13138 ENSG00000169951 "Zinc finger protein 764" Q96H86 16 30553764-30558374 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA003203 Uncertain Approved Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 14: REH - Unknown function" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA003203: AB_1080753" "unprognostic (9.48e-3)" "unprognostic (2.04e-2)" "unprognostic (2.47e-2)" "prognostic favorable (6.84e-4)" "unprognostic (6.62e-2)" "unprognostic (9.75e-3)" "unprognostic (8.26e-3)" "unprognostic (2.64e-3)" "unprognostic (2.00e-1)" "unprognostic (3.64e-1)" "unprognostic (1.77e-3)" "unprognostic (3.43e-2)" "unprognostic (3.55e-1)" "unprognostic (2.87e-1)" "unprognostic (1.40e-1)" "unprognostic (1.09e-1)" "unprognostic (3.05e-1)" 3.5 4.4 2.4 3.1 2.3 4.1 3.6 4.4 2.6 5.0 1.2 4.9 4.8 4.9 1.1 3.5 4.7 2.2 6.6 2.4 2.4 4.2 5.9 3.1 4.5 2.3 2.0 5.6 4.4 3.3 5.0 2.1 2.3 4.8 2.9 2.9 3.5 2.3 3.9 3.5 4.8 1.8 1.5 5.2 6.8 5.8 2.3 3.5 3.5 2.3 2.8 3.7 3.7 2.7 2.9 3.6 6.8 6.6 2.9 2.8 4.1 3.7 2.9 3.5 2.6 2.7 2.8 5.3 4.3 2.1 2.1 4.1 3.6 2.4 2.7 6.0 9.7 3.6 4.5 5.1 3.4 3.4 5.5 2.2 2.9 2.9 3.8 4.6 3.2 12.8 6.8 6.0 3.1 6.6 9.6 5.5 4.0 1.8 4.7 13.0 2.8 7.2 2.8 1.5 13.0 10.1 2.5 5.8 3.6 4.1 5.0 6.2 2.9 4.8 2.6 2.7 3.7 8.1 6.0 4.5 3.4 4.8 6.7 2.3 1.4 4.4 2.9 1.7 3.9 1.8 3.0 3.7 1.8 2.4 3.1 3.0 1.4 7.2 1.8 2.0 2.1 1.8 2.4 2.3 4.4 2.6 2.4 2.4 2.3 2.0 2.3 1.5 2.3 2.7 3.9 0.0 3.2 2.9 5.0 1.7 2.7 1.9 2.8 5.4 3.9 2.8 5.2 7.2 3.1 1.8 0.0 2.6 5.0 4.4 0.0 3.4 0.6 5.3 4.6 3.8 2.4 3.0 1.7 3.0 2.1 2.8 5.6 3.6 1.3 4.6 4.2 2.5 3.7 1.7 1.9 4.2 0.0 3.5 1.2 0.8 3.4 3.2 0.0 0.0 4.2 3.3 6.2 2.5 2.0 3.8 10.4 2.6 3.3 2.6 4.7 2.9 6.3 5.7 6.6 2.6 3.8 10.5 4.3 3.5 0.4 1.0 6.0 2.7 4.4 1.9 ZNF772 DKFZp686I1569 ENSG00000197128 "Zinc finger protein 772" Q68DY9 19 57466663-57477570 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 16.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 26.4" "Low region specificity" "Detected in all" HPA031312 Uncertain Approved Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 21: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Cytosol "HPA031312: AB_10603941" "unprognostic (2.30e-2)" "unprognostic (5.96e-2)" "unprognostic (1.12e-1)" "unprognostic (1.82e-1)" "unprognostic (1.83e-1)" "unprognostic (3.73e-2)" "unprognostic (2.24e-1)" "unprognostic (2.35e-1)" "unprognostic (6.31e-3)" "unprognostic (1.27e-1)" "unprognostic (2.50e-2)" "unprognostic (5.01e-2)" "prognostic favorable (1.02e-6)" "unprognostic (7.99e-2)" "unprognostic (3.75e-1)" "unprognostic (1.43e-1)" "unprognostic (7.93e-2)" 1.8 3.8 2.8 1.7 3.2 1.5 4.8 12.9 3.6 2.9 5.6 1.6 1.7 2.3 5.5 2.4 5.3 2.6 6.9 2.5 3.8 4.1 2.6 2.9 3.4 2.0 2.9 6.2 2.9 11.0 4.5 4.4 1.1 4.5 1.6 14.0 4.1 4.1 5.6 4.3 1.9 2.0 1.4 4.8 2.5 3.7 2.5 6.1 9.1 7.9 4.1 1.9 1.4 3.5 2.9 1.9 11.7 4.9 3.0 6.3 4.8 5.1 6.0 7.8 26.4 0.8 2.6 0.3 3.7 4.4 3.4 0.4 2.5 6.4 9.5 0.0 18.5 9.6 1.1 3.1 4.0 1.2 9.7 4.8 3.0 5.5 10.2 7.1 5.7 3.8 2.9 1.8 7.4 2.1 1.4 2.5 7.4 0.7 5.2 2.6 14.4 9.6 3.7 7.5 12.1 7.5 0.2 2.6 3.7 7.9 7.6 6.2 2.7 7.1 4.6 1.6 5.1 11.5 22.2 3.4 1.5 0.2 7.3 0.2 1.2 1.1 0.3 0.8 1.3 2.1 1.0 0.4 1.5 3.7 1.9 1.0 0.6 1.6 0.9 0.8 0.2 1.0 2.8 3.2 12.9 3.6 2.5 3.8 2.0 2.9 1.1 1.4 2.5 3.5 1.5 6.4 2.6 6.5 2.7 0.6 0.5 0.9 0.6 7.0 2.2 1.5 5.3 2.8 1.6 16.5 6.2 2.3 0.4 1.0 0.0 2.0 0.0 1.0 0.8 2.6 2.4 1.7 4.3 0.4 0.9 1.3 1.1 1.2 2.5 3.8 4.2 3.3 2.6 6.7 4.2 1.4 4.1 4.1 0.5 1.2 0.6 1.6 0.0 1.0 1.2 5.4 1.0 7.5 4.5 0.7 0.5 2.2 0.8 1.2 1.0 2.1 1.7 8.8 0.0 1.1 1.9 0.6 1.3 2.3 1.1 1.8 0.7 1.9 1.5 0.8 ZNF785 FLJ32130 ENSG00000197162 "Zinc finger protein 785" A8K8V0 16 30573740-30585769 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA004010 Approved Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" Cytosol "HPA004010: " "unprognostic (2.85e-2)" "unprognostic (1.29e-1)" "unprognostic (8.25e-2)" "unprognostic (2.47e-1)" "unprognostic (2.35e-1)" "unprognostic (4.15e-2)" "unprognostic (2.54e-4)" "prognostic favorable (8.99e-4)" "unprognostic (1.55e-1)" "unprognostic (2.08e-1)" "prognostic favorable (2.03e-5)" "unprognostic (3.37e-2)" "unprognostic (5.65e-2)" "unprognostic (1.46e-1)" "unprognostic (3.13e-2)" "unprognostic (1.74e-1)" "unprognostic (1.54e-2)" 5.2 5.7 5.7 4.9 6.4 3.1 6.1 9.1 8.3 10.9 2.9 8.1 8.4 9.6 5.4 6.2 8.8 4.4 5.6 5.6 6.2 8.2 5.8 5.8 5.5 6.1 4.7 11.0 8.3 5.7 9.5 3.6 4.8 10.2 4.7 6.5 8.2 5.1 6.0 7.4 8.2 4.2 2.6 7.6 7.5 3.3 6.3 4.4 8.0 3.6 3.9 9.0 8.5 9.8 5.7 0.5 5.4 7.1 6.5 7.2 1.7 4.9 4.3 5.0 3.7 7.5 8.9 5.9 5.6 4.7 0.3 8.0 0.1 3.2 2.9 4.0 1.4 7.2 17.4 1.8 4.8 0.6 11.8 4.8 6.7 3.3 3.1 4.2 5.3 1.0 6.9 7.1 4.6 9.8 7.3 6.7 3.0 2.2 3.2 18.8 6.1 2.9 4.6 5.8 14.7 10.4 4.0 5.0 3.0 3.2 6.3 6.1 8.1 1.9 5.2 4.4 0.4 0.9 3.3 2.4 6.3 4.3 8.1 2.8 1.1 0.4 0.9 0.6 0.9 2.7 1.1 0.7 0.8 1.1 1.3 1.0 1.9 1.3 2.4 2.3 1.5 0.5 5.7 6.4 9.1 8.3 5.6 6.2 6.1 4.7 4.8 2.6 6.3 9.8 5.3 0.0 3.4 11.1 5.3 1.0 7.6 3.4 6.8 10.7 4.1 2.4 1.8 4.3 2.5 7.3 20.9 1.3 14.3 4.7 5.9 3.9 0.1 3.5 11.1 7.1 12.0 3.4 14.1 3.7 1.1 5.2 3.6 4.5 0.0 14.8 3.6 3.5 2.6 13.5 13.6 5.2 0.0 5.0 3.1 0.8 13.4 3.3 5.4 6.5 6.0 5.8 15.5 6.6 11.4 4.2 8.1 13.2 1.4 7.0 6.6 2.4 4.0 12.0 0.0 6.2 4.6 5.3 3.1 3.1 2.6 0.8 4.7 6.8 7.4 5.1 ZNF852 ENSG00000178917 "Zinc finger protein 852" Q6ZMS4 3 44494847-44510636 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 9.0;Oligodendrocytes: 9.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "HPA048312, HPA071850" Uncertain Approved Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 43: Cardiomyocytes - Nuclear processes" Cytosol "HPA048312: AB_2680352, HPA071850: AB_2686458" "unprognostic (2.64e-1)" "unprognostic (2.62e-1)" "unprognostic (5.93e-3)" "unprognostic (1.73e-1)" "unprognostic (2.29e-2)" "unprognostic (1.30e-3)" "unprognostic (3.47e-2)" "unprognostic (2.55e-2)" "unprognostic (5.11e-2)" "unprognostic (1.43e-1)" "unprognostic (3.80e-2)" "unprognostic (1.03e-1)" "unprognostic (6.62e-4)" "unprognostic (4.70e-2)" "unprognostic (2.29e-1)" "unprognostic (8.05e-2)" "unprognostic (1.11e-2)" 1.3 1.4 0.7 2.5 0.6 1.6 2.1 3.4 0.9 2.0 3.6 1.9 1.7 2.2 1.7 0.9 1.6 1.3 0.5 0.8 1.1 1.7 1.7 1.8 2.5 0.9 0.7 2.5 2.1 2.9 0.8 2.3 1.1 2.6 3.1 0.9 3.7 2.1 0.5 2.5 2.0 1.9 0.3 2.7 3.0 1.3 1.2 2.9 1.7 0.9 3.2 1.1 0.8 0.7 1.0 1.4 3.9 6.6 0.8 2.3 2.4 1.0 1.3 2.1 3.1 2.1 1.1 3.2 0.7 0.8 0.9 0.8 4.3 1.1 2.8 2.8 1.5 3.1 6.5 1.9 1.2 3.3 5.7 0.8 1.9 2.7 1.1 2.2 1.7 3.3 3.7 1.4 2.5 0.2 3.0 3.8 2.4 1.2 0.8 1.5 4.3 1.9 1.6 3.2 3.0 2.5 2.2 0.9 0.7 6.6 2.2 3.5 2.8 2.6 2.5 1.4 1.0 2.4 1.9 1.9 1.1 2.6 1.7 0.0 0.4 0.7 0.2 0.5 0.3 1.1 0.5 0.3 0.2 0.9 0.5 0.7 0.6 0.4 0.2 1.4 0.2 0.1 0.7 0.6 3.4 0.9 0.8 1.1 0.9 0.7 1.1 0.3 1.2 0.7 2.0 0.0 5.4 5.9 2.3 3.3 0.8 0.9 1.2 2.1 1.5 1.5 1.8 2.8 1.4 0.0 2.1 0.8 5.1 0.8 3.9 1.9 0.3 2.6 1.6 2.0 0.0 3.2 5.7 1.4 0.9 1.4 1.1 1.5 1.3 1.8 2.2 1.4 0.7 1.7 6.8 0.9 2.0 0.3 1.0 0.4 0.6 1.4 1.8 1.9 1.4 2.8 3.1 9.0 9.2 1.5 0.1 1.2 6.8 1.1 1.0 1.0 4.2 1.6 0.0 2.4 1.6 2.0 1.6 0.5 1.8 0.3 2.3 1.6 0.8 0.9 ZNRD2 "p27, SSSCA1" ENSG00000173465 "Zinc ribbon domain containing 2" O60232 11 65570460-65573942 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 44.9;Cytotrophoblasts: 81.1;Extravillous trophoblasts: 84.5;Hofbauer cells: 57.9;Syncytiotrophoblasts: 79.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA039789, HPA064670" Uncertain Approved Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA039789: AB_2676680, HPA064670: AB_2732718" "unprognostic (9.32e-2)" "unprognostic (3.57e-2)" "unprognostic (1.03e-1)" "unprognostic (2.04e-2)" "unprognostic (1.08e-1)" "unprognostic (3.35e-3)" "unprognostic (3.03e-2)" "unprognostic (2.65e-1)" "unprognostic (4.92e-2)" "unprognostic (1.36e-2)" "unprognostic (1.20e-1)" "unprognostic (3.11e-1)" "unprognostic (5.75e-2)" "unprognostic (2.23e-1)" "unprognostic (1.95e-1)" "unprognostic (5.86e-2)" "unprognostic (9.34e-2)" 39.1 46.0 16.3 32.8 20.2 48.2 38.9 14.0 28.5 38.4 9.1 50.7 22.5 45.9 8.8 41.5 42.5 20.2 50.5 21.7 14.4 45.4 47.6 38.7 32.8 16.1 16.5 38.8 61.8 19.9 31.2 23.3 14.8 41.9 9.1 7.2 45.2 20.7 104.0 42.4 30.9 16.1 9.9 41.4 41.2 50.6 14.7 25.7 35.9 37.0 16.4 43.1 35.7 18.7 79.4 61.5 39.2 72.0 23.5 20.1 61.0 55.0 31.2 50.8 35.5 59.1 79.9 75.3 93.4 30.8 37.0 68.9 29.5 59.2 18.1 54.7 45.8 67.7 61.0 48.0 32.8 81.6 53.8 31.5 40.2 39.4 40.2 39.2 40.6 68.0 79.8 97.0 28.8 110.0 100.1 72.1 63.9 28.2 104.7 77.4 29.0 142.1 30.3 40.2 78.2 81.3 33.4 82.3 79.8 15.9 111.4 41.3 47.3 92.1 50.5 111.1 69.0 69.0 102.8 66.1 74.3 57.1 83.5 15.4 62.8 27.1 56.5 55.5 59.1 103.5 57.2 57.4 51.5 89.5 66.1 57.7 20.1 85.4 37.5 85.9 69.8 50.7 16.3 20.2 14.0 28.5 21.7 14.4 16.1 16.5 14.8 9.9 14.7 18.7 16.7 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.9 0.0 0.0 0.0 0.0 81.1 16.2 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 84.5 13.5 0.0 0.0 0.0 0.0 0.0 0.0 57.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 79.9 2.3 0.0 0.0 0.0 ZSWIM6 KIAA1577 ENSG00000130449 "Zinc finger SWIM-type containing 6" Q9HCJ5 5 61332258-61546172 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 500.1;Microglial cells: 365.4;Oligodendrocyte precursor cells: 765.6;Oligodendrocytes: 740.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPMI-8226: 44.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035938 Uncertain Approved Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 70: Brain - Nervous system development" "Cluster 25: RPMI-8226 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "HPA035938: AB_10672077" "unprognostic (2.22e-1)" "unprognostic (2.08e-2)" "unprognostic (1.12e-1)" "unprognostic (2.10e-1)" "unprognostic (2.70e-1)" "unprognostic (6.69e-2)" "unprognostic (2.00e-1)" "unprognostic (6.96e-3)" "unprognostic (6.16e-2)" "unprognostic (1.40e-2)" "unprognostic (2.03e-1)" "unprognostic (1.94e-1)" "unprognostic (1.68e-2)" "unprognostic (7.50e-3)" "unprognostic (1.11e-1)" "unprognostic (3.63e-1)" "unprognostic (1.99e-1)" 8.1 5.4 11.0 8.9 17.0 3.8 5.8 13.0 14.3 6.6 4.1 9.6 6.0 5.0 5.5 8.8 6.3 9.5 4.8 11.0 12.0 5.1 7.8 13.4 5.7 15.7 13.6 7.2 7.7 5.8 6.4 7.8 14.9 8.3 10.7 8.3 6.9 6.4 3.4 5.3 7.5 6.2 12.4 7.0 10.0 7.4 14.2 6.9 6.5 2.5 5.0 7.6 8.4 26.5 6.0 7.8 35.4 2.5 7.5 13.6 3.0 7.9 7.1 8.6 13.2 3.1 9.4 1.5 6.7 9.9 13.7 5.1 7.9 9.6 12.0 25.0 7.4 2.9 16.3 1.7 9.9 1.9 4.1 9.9 7.0 20.2 17.2 11.8 21.3 3.3 0.9 29.3 35.4 4.3 1.6 3.8 5.4 1.8 5.8 11.8 10.3 44.4 14.1 7.7 7.2 11.3 18.7 1.1 7.3 13.7 3.1 7.7 29.8 7.1 9.2 9.9 11.4 5.1 0.8 3.2 11.0 2.3 15.4 0.9 1.1 0.5 0.0 0.9 0.3 0.2 0.1 0.1 0.5 0.3 0.1 0.1 1.6 0.4 1.3 1.3 0.1 0.2 11.0 17.0 13.0 14.3 11.0 12.0 15.7 13.6 14.9 12.4 14.2 26.5 24.5 25.6 12.6 500.1 13.3 47.4 80.2 12.0 42.1 6.9 25.8 20.4 12.2 25.8 27.1 11.0 10.4 0.4 29.5 38.4 1.9 12.0 12.7 47.4 37.4 23.6 14.2 1.7 223.4 12.9 0.5 22.7 28.1 86.1 14.5 9.6 27.8 8.0 25.9 8.4 167.7 25.8 14.2 59.3 49.0 8.5 5.6 53.3 16.0 365.4 34.0 15.6 2.1 765.6 740.4 19.2 30.2 6.4 14.3 40.6 9.4 4.9 28.8 5.1 6.6 19.5 22.7 18.9 18.8 32.2 39.9 1.4 15.7 27.1 19.8 58.3 ZSWIM7 SWS1 ENSG00000214941 "Zinc finger SWIM-type containing 7" Q19AV6 17 15976560-15999717 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054681 Uncertain Uncertain Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA054681: AB_2682572" "unprognostic (3.07e-2)" "unprognostic (5.51e-2)" "unprognostic (1.58e-1)" "prognostic favorable (3.54e-5)" "unprognostic (1.58e-1)" "unprognostic (1.15e-1)" "unprognostic (1.75e-2)" "unprognostic (8.28e-2)" "unprognostic (4.61e-2)" "unprognostic (3.82e-2)" "prognostic favorable (1.77e-4)" "unprognostic (4.23e-2)" "unprognostic (1.84e-2)" "unprognostic (8.56e-2)" "unprognostic (2.45e-3)" "unprognostic (8.80e-3)" "unprognostic (1.70e-1)" 12.5 18.0 6.9 6.0 7.2 4.3 12.6 6.8 10.4 11.8 6.2 12.9 7.3 11.7 4.8 8.5 10.9 4.4 18.2 7.3 7.8 14.5 13.8 10.1 7.2 7.4 7.1 15.7 12.6 6.6 16.2 5.4 7.5 10.8 4.6 5.6 9.3 4.7 32.7 10.9 10.1 5.4 6.8 13.9 10.2 5.8 7.7 4.6 11.7 10.2 3.7 10.4 10.4 7.5 17.2 24.5 12.4 30.1 5.1 4.8 15.1 11.3 4.4 11.7 8.6 4.6 4.9 8.1 9.8 12.2 3.5 5.5 4.1 8.9 5.5 8.7 14.1 9.3 11.5 9.7 12.1 7.5 15.1 11.7 15.4 6.4 11.0 1.7 15.1 21.2 5.9 4.5 6.1 23.2 26.2 17.4 8.1 25.0 14.4 16.2 31.7 13.1 10.6 9.0 4.4 18.9 17.5 17.4 12.4 33.2 12.5 1.8 21.5 18.9 6.4 4.9 9.9 2.3 6.3 9.8 16.2 9.3 16.3 28.0 27.2 12.0 13.6 27.5 14.6 26.8 15.9 13.1 42.0 24.6 18.8 18.0 1.6 18.0 19.8 25.9 12.6 19.7 6.9 7.2 6.8 10.4 7.3 7.8 7.4 7.1 7.5 6.8 7.7 7.5 42.4 35.3 54.5 16.6 35.7 25.6 33.7 50.0 37.0 38.4 56.0 65.0 65.0 67.2 32.7 40.5 62.6 99.9 39.2 35.0 86.1 56.5 13.6 32.9 40.0 33.9 50.8 24.0 16.1 52.0 58.9 29.5 21.9 27.6 55.2 52.3 37.5 55.2 49.7 18.5 13.4 37.1 59.0 55.4 37.8 14.4 45.4 53.0 55.2 15.0 46.9 60.1 53.5 14.6 21.9 50.6 35.7 39.9 24.5 37.0 50.0 134.5 35.8 56.9 26.3 33.9 30.6 87.1 74.1 28.8 27.6 72.8 29.1 71.2 36.3 28.8